BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q86SF2 (657 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 6IWR-A nrPDB 1246 0.0 2D7R-A nrPDB 399 e-111 5AJO-A nrPDB 320 2e-87 5NQA-A nrPDB 310 1e-84 1IT0-A nrPDB 42 0.001 2Z87-A nrPDB 41 0.002 2Z49-A nrPDB 34 0.16 6HNQ-B nrPDB 32 0.69 3JAJ-z nrPDB 32 0.69 5L3Q-A nrPDB 32 0.70 6FRK-x nrPDB 32 0.81 3KT6-A nrPDB 31 1.5 3LKZ-A nrPDB 31 1.5 4ZFY-B nrPDB 31 1.9 1MJF-A nrPDB 31 2.1 5C5V-A nrPDB 31 2.1 1NYR-A nrPDB 30 4.1 5VAT-A nrPDB 30 4.7 2VSU-C nrPDB 29 8.2 >6IWR-A nrPDB Length = 597 Score = 1246 bits (3225), Expect = 0.0, Method: Compositional matrix adjust. Identities = 597/597 (100%), Positives = 597/597 (100%) Query: 61 PGEDRFKPVVPWPHVEGVEVDLESIRRINKAKNEQEHHAGGDSQKDIMQRQYLTFKPQTF 120 PGEDRFKPVVPWPHVEGVEVDLESIRRINKAKNEQEHHAGGDSQKDIMQRQYLTFKPQTF Sbjct: 1 PGEDRFKPVVPWPHVEGVEVDLESIRRINKAKNEQEHHAGGDSQKDIMQRQYLTFKPQTF 60 Query: 121 TYHDPVLRPGILGNFEPKEPEPPGVVGGPGEKAKPLVLGPEFKQAIQASIKEFGFNMVAS 180 TYHDPVLRPGILGNFEPKEPEPPGVVGGPGEKAKPLVLGPEFKQAIQASIKEFGFNMVAS Sbjct: 61 TYHDPVLRPGILGNFEPKEPEPPGVVGGPGEKAKPLVLGPEFKQAIQASIKEFGFNMVAS 120 Query: 181 DMISLDRSVNDLRQEECKYWHYDENLLTSSVVIVFHNEGWSTLMRTVHSVIKRTPRKYLA 240 DMISLDRSVNDLRQEECKYWHYDENLLTSSVVIVFHNEGWSTLMRTVHSVIKRTPRKYLA Sbjct: 121 DMISLDRSVNDLRQEECKYWHYDENLLTSSVVIVFHNEGWSTLMRTVHSVIKRTPRKYLA 180 Query: 241 EIVLIDDFSNKEHLKEKLDEYIKLWNGLVKVFRNERREGLIQARSIGAQKAKLGQVLIYL 300 EIVLIDDFSNKEHLKEKLDEYIKLWNGLVKVFRNERREGLIQARSIGAQKAKLGQVLIYL Sbjct: 181 EIVLIDDFSNKEHLKEKLDEYIKLWNGLVKVFRNERREGLIQARSIGAQKAKLGQVLIYL 240 Query: 301 DAHCEVAVNWYAPLVAPISKDRTICTVPLIDVINGNTYEIIPQGGGDEDGYARGAWDWSM 360 DAHCEVAVNWYAPLVAPISKDRTICTVPLIDVINGNTYEIIPQGGGDEDGYARGAWDWSM Sbjct: 241 DAHCEVAVNWYAPLVAPISKDRTICTVPLIDVINGNTYEIIPQGGGDEDGYARGAWDWSM 300 Query: 361 LWKRVPLTPQEKRLRKTKTEPYRSPAMAGGLFAIEREFFFELGLYDPGLQIWGGENFEIS 420 LWKRVPLTPQEKRLRKTKTEPYRSPAMAGGLFAIEREFFFELGLYDPGLQIWGGENFEIS Sbjct: 301 LWKRVPLTPQEKRLRKTKTEPYRSPAMAGGLFAIEREFFFELGLYDPGLQIWGGENFEIS 360 Query: 421 YKIWQCGGKLLFVPCSRVGHIYRLEGWQGNPPPIYVGSSPTLKNYVRVVEVWWDEYKDYF 480 YKIWQCGGKLLFVPCSRVGHIYRLEGWQGNPPPIYVGSSPTLKNYVRVVEVWWDEYKDYF Sbjct: 361 YKIWQCGGKLLFVPCSRVGHIYRLEGWQGNPPPIYVGSSPTLKNYVRVVEVWWDEYKDYF 420 Query: 481 YASRPESQALPYGDISELKKFREDHNCKSFKWFMEEIAYDITSHYPLPPKNVDWGEIRGF 540 YASRPESQALPYGDISELKKFREDHNCKSFKWFMEEIAYDITSHYPLPPKNVDWGEIRGF Sbjct: 421 YASRPESQALPYGDISELKKFREDHNCKSFKWFMEEIAYDITSHYPLPPKNVDWGEIRGF 480 Query: 541 ETAYCIDSMGKTNGGFVELGPCHRMGGNQLFRINEANQLMQYDQCLTKGADGSKVMITHC 600 ETAYCIDSMGKTNGGFVELGPCHRMGGNQLFRINEANQLMQYDQCLTKGADGSKVMITHC Sbjct: 481 ETAYCIDSMGKTNGGFVELGPCHRMGGNQLFRINEANQLMQYDQCLTKGADGSKVMITHC 540 Query: 601 NLNEFKEWQYFKNLHRFTHIPSGKCLDRSEVLHQVFISNCDSSKTTQKWEMNNIHSV 657 NLNEFKEWQYFKNLHRFTHIPSGKCLDRSEVLHQVFISNCDSSKTTQKWEMNNIHSV Sbjct: 541 NLNEFKEWQYFKNLHRFTHIPSGKCLDRSEVLHQVFISNCDSSKTTQKWEMNNIHSV 597 >2D7R-A nrPDB Length = 570 Score = 399 bits (1026), Expect = e-111, Method: Compositional matrix adjust. Identities = 216/524 (41%), Positives = 314/524 (59%), Gaps = 30/524 (5%) Query: 148 GPGEKAKPLVLGPEFKQAIQASIKEFGFNMVASDMISLDRSVNDLRQEECKYWHYDENLL 207 G GE+ +P + + + + +E GFN+ SD ISL+RS+ D+R C Y E L Sbjct: 55 GNGEQGRPYPMTD--AERVDQAYRENGFNIYVSDKISLNRSLPDIRHPNCNSKRYLETLP 112 Query: 208 TSSVVIVFHNEGWSTLMRTVHSVIKRTPRKYLAEIVLIDDFSNKEHLKEKLDEYIKLWNG 267 +S++I FHNEGWS+L+RTVHSV+ R+P + +AEIVL+DDFS++EHLK+ L++Y+ L+ Sbjct: 113 NTSIIIPFHNEGWSSLLRTVHSVLNRSPPELVAEIVLVDDFSDREHLKKPLEDYMALFPS 172 Query: 268 LVKVFRNERREGLIQARSIGAQKAKLGQVLIYLDAHCEVAVNWYAPLVAPISKDRTICTV 327 V++ R ++REGLI+ R +GA A G V+ +LD+HCE VNW PL+ I+++R Sbjct: 173 -VRILRTKKREGLIRTRMLGASVAT-GDVITFLDSHCEANVNWLPPLLDRIARNRKTIVC 230 Query: 328 PLIDVINGNTYEIIPQGGGDEDGYARGAWDWSMLWKRVPLTPQEKRLRKTKTEPYRSPAM 387 P+IDVI+ + + Q G RGA+DW M +KR+P+ P+ + + ++P+ SP M Sbjct: 231 PMIDVIDHDDFRYETQAG----DAMRGAFDWEMYYKRIPIPPELQ--KADPSDPFESPVM 284 Query: 388 AGGLFAIEREFFFELGLYDPGLQIWGGENFEISYKIWQCGGKLLFVPCSRVGHIYRLEGW 447 AGGLFA++R++F+ELG YDPGL+IWGGE +EIS+K+W CGG++ +PCSRVGHIYR Sbjct: 285 AGGLFAVDRKWFWELGGYDPGLEIWGGEQYEISFKVWMCGGRMEDIPCSRVGHIYR---- 340 Query: 448 QGNPPPIYVGSSPTLKNYVRVVEVWWDEYKDYFYASRPESQALPYGDISELKKFREDHNC 507 + P + G S +N RV EVW DEY +Y Y RPE + L GD++ KK R NC Sbjct: 341 KYVPYKVPAGVS-LARNLKRVAEVWMDEYAEYIYQRRPEYRHLSAGDVAVQKKLRSSLNC 399 Query: 508 KSFKWFMEEIAYDITSHY-PLPPKNVDWGEIRGFETAYCIDSMGKTNGGFVELGPCHRMG 566 KSFKWFM +IA+D+ Y P+ P WGEIR T C D+ G + L C R Sbjct: 400 KSFKWFMTKIAWDLPKFYPPVEPPAAAWGEIRNVGTGLCADTKHGALGSPLRLEGCVRGR 459 Query: 567 GN------QLFRINEANQLMQYDQ------CLTKGADGSKVMITHC-NLNEFKEWQYFKN 613 G Q+F + D C + S V + C ++ + W+Y K+ Sbjct: 460 GEAAWNNMQVFTFTWREDIRPGDPQHTKKFCFDAISHTSPVTLYDCHSMKGNQLWKYRKD 519 Query: 614 LHRFTHIPSGKCLDRSEVLHQVFISNCDSSKTTQKWEMNNIHSV 657 H SG C+D SE H++F++ C+ S TQ+W + +S Sbjct: 520 -KTLYHPVSGSCMDCSESDHRIFMNTCNPSSLTQQWLFEHTNST 562 >5AJO-A nrPDB Length = 571 Score = 320 bits (819), Expect = 2e-87, Method: Compositional matrix adjust. Identities = 177/496 (35%), Positives = 289/496 (58%), Gaps = 30/496 (6%) Query: 139 EPEPPGVVGGPGEKAKPLVLGPEFKQAIQASIKEFGFNMVASDMISLDRSVNDLRQEECK 198 E PPG V P + V G + Q FN V SD + +DR++ D R ++C+ Sbjct: 69 ETLPPGKVRWPDFNQEAYVGGTMVRSG-QDPYARNKFNQVESDKLRMDRAIPDTRHDQCQ 127 Query: 199 YWHYDENLLTSSVVIVFHNEGWSTLMRTVHSVIKRTPRKYLAEIVLIDDFSNKEHLKEKL 258 + +L +SVVI FHNE S L+RTV SV+K++P + EI+L+DD+SN L Sbjct: 128 RKQWRVDLPATSVVITFHNEARSALLRTVVSVLKKSPPHLIKEIILVDDYSNDPEDGALL 187 Query: 259 DEYIKLWNGLVKVFRNERREGLIQARSIGAQKAKLGQVLIYLDAHCEVAVNWYAPLVAPI 318 + K V+V RN+RREGL+++R GA A+ +VL +LD+HCE +W PL+ + Sbjct: 188 GKIEK-----VRVLRNDRREGLMRSRVRGADAAQ-AKVLTFLDSHCECNEHWLEPLLERV 241 Query: 319 SKDRTICTVPLIDVINGNTYEIIPQGGGDEDGYARGAWDWSMLWKRVPLTPQEKRLRK-T 377 ++DRT P+IDVIN + ++ + G D +G +DW++++K +TP+++R R+ Sbjct: 242 AEDRTRVVSPIIDVINMDNFQYV---GASAD--LKGGFDWNLVFKWDYMTPEQRRSRQGN 296 Query: 378 KTEPYRSPAMAGGLFAIEREFFFELGLYDPGLQIWGGENFEISYKIWQCGGKLLFVPCSR 437 P ++P +AGGLF +++ +F ELG YD + +WGGEN EIS+++WQCGG L +PCSR Sbjct: 297 PVAPIKTPMIAGGLFVMDKFYFEELGKYDMMMDVWGGENLEISFRVWQCGGSLEIIPCSR 356 Query: 438 VGHIYRLEGWQGNPPPIYVGSSPTL--KNYVRVVEVWWDEYKDYFYASRPESQALPYGDI 495 VGH++R + P + G S T+ +N R EVW DEYK+++YA+ P ++ +PYG+I Sbjct: 357 VGHVFRKQH-----PYTFPGGSGTVFARNTRRAAEVWMDEYKNFYYAAVPSARNVPYGNI 411 Query: 496 SELKKFREDHNCKSFKWFMEEIAYDITSHYPLPP-KNVDWGEIRGFETAYCIDSMGKTNG 554 + R+ +CK FKW++E + ++ +P +++ +G ++ + C+D++G Sbjct: 412 QSRLELRKKLSCKPFKWYLENVYPELR----VPDHQDIAFGALQ--QGTNCLDTLGHFAD 465 Query: 555 GFVELGPCHRMGGNQLFRINEANQLMQYDQCLT--KGADGSKVMITHCNLNEFKE-WQYF 611 G V + CH GGNQ + + + + D CLT A GS + + C ++ ++ W+ Sbjct: 466 GVVGVYECHNAGGNQEWALTKEKSVKHMDLCLTVVDRAPGSLIKLQGCREDDSRQKWEQI 525 Query: 612 KNLHRFTHIPSGKCLD 627 + + H+ S CLD Sbjct: 526 EGNSKLRHVGSNLCLD 541 >5NQA-A nrPDB Length = 578 Score = 310 bits (794), Expect = 1e-84, Method: Compositional matrix adjust. Identities = 194/535 (36%), Positives = 282/535 (52%), Gaps = 40/535 (7%) Query: 137 PKEPEPPGVVGGPGE--KAKPLVLGPEFKQAIQASIKEFGFNMVASDMISLDRSVNDLRQ 194 P +PP GE KA L L + + + I+ + N+ SD ISL R + D R Sbjct: 62 PLYKKPPADSRALGEWGKASKLQLNEDELKQQEELIERYAINIYLSDRISLHRHIEDKRM 121 Query: 195 EECKYWHYD-ENLLTSSVVIVFHNEGWSTLMRTVHSVIKRTPRKYLAEIVLIDDFSNKEH 253 ECK ++ L T+SV+I F+NE WSTL+RT+HSV++ +P L EI+L+DD S++ + Sbjct: 122 YECKSQKFNYRTLPTTSVIIAFYNEAWSTLLRTIHSVLETSPAVLLKEIILVDDLSDRVY 181 Query: 254 LKEKLDEYIKLWNGLVKVFRNERREGLIQARSIGAQKAKLGQVLIYLDAHCEVAVNWYAP 313 LK +L+ YI + V++ R +REGL++AR IGA A G VL +LD HCE W P Sbjct: 182 LKTQLETYISNLDR-VRLIRTNKREGLVRARLIGATFAT-GDVLTFLDCHCECNSGWLEP 239 Query: 314 LVAPISKDRTICTVPLIDVINGNTYEIIPQGGGDEDGYARGAWDWSMLWKRVPLTPQEKR 373 L+ I +D T P+ID I+ NT+E Q G G +DW + ++ + QE+ Sbjct: 240 LLERIGRDETAVVCPVIDTIDWNTFEFYMQIGEP----MIGGFDWRLTFQWHSVPKQERD 295 Query: 374 LRKTKTEPYRSPAMAGGLFAIEREFFFELGLYDPGLQIWGGENFEISYKIWQCGGKLLFV 433 R ++ +P RSP MAGGLFA+ +++F LG YD G+++WGGEN E+S+++WQCGGKL Sbjct: 296 RRISRIDPIRSPTMAGGLFAVSKKYFQYLGTYDTGMEVWGGENLELSFRVWQCGGKLEIH 355 Query: 434 PCSRVGHIYRLEGWQGNPPPIYVGSSPTLKNYVRVVEVWWDEYKDYFYASRPESQALPYG 493 PCS VGH++ P L+N R EVW DEYK++FY P ++ YG Sbjct: 356 PCSHVGHVF--------PKRAPYARPNFLQNTARAAEVWMDEYKEHFYNRNPPARKEAYG 407 Query: 494 DISELKKFREDHNCKSFKWFMEEIAYDITSHYPLPPKNVDW-GEIRGFE-TAYCIDSMGK 551 DISE K RE CKSF W+++ + ++ +P W G IR ++ C+D Sbjct: 408 DISERKLLRERLRCKSFDWYLKNVFPNLH----VPEDRPGWHGAIRSRGISSECLDYNSP 463 Query: 552 TN---GGFVELGPCHRMGGNQLFRINEANQLMQYDQ----CLTKGADGSKVMITHCNLNE 604 N G + L CH GGNQ F +N+ ++++ C + V + +C + Sbjct: 464 DNNPTGANLSLFGCHGQGGNQFFEYT-SNKEIRFNSVTELCAEVPEQKNYVGMQNCPKDG 522 Query: 605 FKE-----WQYFKNLHRFTHIPSGKCLD---RSEVLHQVFISNCDSSKTTQKWEM 651 F W +FK H SG CL E V + CD+ Q W Sbjct: 523 FPVPANIIW-HFKEDGTIFHPHSGLCLSAYRTPEGRPDVQMRTCDALDKNQIWSF 576 >1IT0-A nrPDB Length = 436 Score = 41.6 bits (96), Expect = 0.001, Method: Compositional matrix adjust. Identities = 30/98 (30%), Positives = 49/98 (50%), Gaps = 7/98 (7%) Query: 535 GEIRGFETAYCID--SMGKTNGGFVELGPCHRMGGNQLFRINEANQLMQY-DQCLTKG-- 589 G+I+G + C+D + T+G V+L CH NQ + +A +L Y D+CL Sbjct: 313 GQIKGVGSGRCLDVPNASTTDGTQVQLYDCHSA-TNQQWTYTDAGELRVYGDKCLDAAGT 371 Query: 590 ADGSKVMITHCNLNEFKEWQYFKNLHRFTHIPSGKCLD 627 +G+KV I C + ++W+ + + SG CLD Sbjct: 372 GNGTKVQIYSCWGGDNQKWR-LNSDGSIVGVQSGLCLD 408 >2Z87-A nrPDB Length = 624 Score = 41.2 bits (95), Expect = 0.002, Method: Compositional matrix adjust. Identities = 53/236 (22%), Positives = 101/236 (42%), Gaps = 23/236 (9%) Query: 206 LLTSSVVIVFHNEGWSTLMRTVHSVIKRTPRKYLAEIVLIDDFSNKEHLKEKLDEYIKLW 265 L+ + IV + ++ + + Y E+++ DD S KE+++E + E+ L Sbjct: 89 LIIDGLSIVIPTYNRAKILAITLACLCNQKTIYDYEVIVADDGS-KENIEEIVREFESLL 147 Query: 266 NGLVKVFRNERREGLIQARSIGAQKAKLGQVLIYLDAHCEVAVN--WYAPLVAPISKDRT 323 N + V + + L R++G + AK V I LD C++A N W + ++ D Sbjct: 148 N-IKYVRQKDYGYQLCAVRNLGLRAAKYNYVAI-LD--CDMAPNPLWVQSYMELLAVDDN 203 Query: 324 ICTVPLIDVINGNTYEI------------IPQGGGDEDGYARGAWDWSMLWKRVPLTPQE 371 + + I+ + + IP+ + + + S+ W R+ Sbjct: 204 VALIGPRKYIDTSKHTYLDFLSQKSLINEIPEIITNNQVAGKVEQNKSVDW-RIEHFKNT 262 Query: 372 KRLRKTKTEPYRSPAMAGGLFAIEREFFFELGLYDPGLQIWGGENFEISYKIWQCG 427 LR T P+R +GG A +++ F G +D WGGE+ E Y++++ G Sbjct: 263 DNLRLCNT-PFR--FFSGGNVAFAKKWLFRAGWFDEEFTHWGGEDNEFGYRLYREG 315 >2Z49-A nrPDB Length = 432 Score = 34.3 bits (77), Expect = 0.16, Method: Compositional matrix adjust. Identities = 30/116 (25%), Positives = 48/116 (41%), Gaps = 22/116 (18%) Query: 532 VDWGEIRGFETAYCIDSMGKTNGGFVELGPCHRMGGNQLFRINEA---NQLMQYDQCLT- 587 +D GE+R F++ C+D +G G + C + Q+ + N+ Y C T Sbjct: 8 LDIGELRSFKSKQCVDIVGNQGSGNIATYDCDGLSDQQIIICGDGTIRNEARNY--CFTP 65 Query: 588 KGADGSKVMITHCNLN-EFKEWQYFKNLHRFT---------------HIPSGKCLD 627 G+ + VM + C L E Q ++ R T ++ SGKCLD Sbjct: 66 DGSGNANVMSSPCTLYPEIPSSQRWRQGRRKTFTDNGGIEQVATEIINLASGKCLD 121 >6HNQ-B nrPDB Length = 345 Score = 32.3 bits (72), Expect = 0.69, Method: Compositional matrix adjust. Identities = 29/94 (30%), Positives = 51/94 (54%), Gaps = 6/94 (6%) Query: 210 SVVIVFHNEGWSTLMRTVHSVIKRTPRKYLAEIVLIDDFSNKEHLKEKLDEYIKLWNGLV 269 SV++ N G L RT+ SV+ +T + E+++IDD SN E L+ IK + GLV Sbjct: 23 SVIMPTFNNG-EKLHRTISSVLNQTMKSTDYELIIIDDHSNDNG--ETLN-VIKKYKGLV 78 Query: 270 KVFRNERREGLIQA-RSIGAQKAKLGQVLIYLDA 302 + + ++ G R+ G + +K + + +LD+ Sbjct: 79 RFKQLKKNSGNASVPRNTGLKMSK-AEYVFFLDS 111 >3JAJ-z nrPDB Length = 426 Score = 32.3 bits (72), Expect = 0.69, Method: Compositional matrix adjust. Identities = 26/84 (30%), Positives = 39/84 (46%), Gaps = 9/84 (10%) Query: 372 KRLRKTKTEPYRSPAMAGGLF---AIEREFFFEL-GLYDPGLQIWG---GENFEISYKIW 424 K+LR+ MA GL I+ F EL L DPG++ W G+ I + Sbjct: 47 KQLRENVKSAIDLEEMASGLNKRKMIQHAVFKELVKLVDPGVKAWTPTKGKQNVIMFVGL 106 Query: 425 QCGGKLLFVPCSRVGHIYRLEGWQ 448 Q GK CS++ + Y+ +GW+ Sbjct: 107 QGSGKT--TTCSKLAYYYQRKGWK 128 >5L3Q-A nrPDB Length = 442 Score = 32.3 bits (72), Expect = 0.70, Method: Compositional matrix adjust. Identities = 26/84 (30%), Positives = 39/84 (46%), Gaps = 9/84 (10%) Query: 372 KRLRKTKTEPYRSPAMAGGLF---AIEREFFFEL-GLYDPGLQIWG---GENFEISYKIW 424 K+LR+ MA GL I+ F EL L DPG++ W G+ I + Sbjct: 56 KQLRENVKSAIDLEEMASGLNKRKMIQHAVFKELVKLVDPGVKAWTPTKGKQNVIMFVGL 115 Query: 425 QCGGKLLFVPCSRVGHIYRLEGWQ 448 Q GK CS++ + Y+ +GW+ Sbjct: 116 QGSGKT--TTCSKLAYYYQRKGWK 137 >6FRK-x nrPDB Length = 504 Score = 32.0 bits (71), Expect = 0.81, Method: Compositional matrix adjust. Identities = 26/84 (30%), Positives = 39/84 (46%), Gaps = 9/84 (10%) Query: 372 KRLRKTKTEPYRSPAMAGGLF---AIEREFFFEL-GLYDPGLQIWG---GENFEISYKIW 424 K+LR+ MA GL I+ F EL L DPG++ W G+ I + Sbjct: 50 KQLRENVKSAIDLEEMASGLNKRKMIQHAVFKELVKLVDPGVKAWTPTKGKQNVIMFVGL 109 Query: 425 QCGGKLLFVPCSRVGHIYRLEGWQ 448 Q GK CS++ + Y+ +GW+ Sbjct: 110 QGSGKT--TTCSKLAYYYQRKGWK 131 >3KT6-A nrPDB Length = 438 Score = 31.2 bits (69), Expect = 1.5, Method: Compositional matrix adjust. Identities = 25/69 (36%), Positives = 35/69 (50%), Gaps = 4/69 (5%) Query: 343 QGGGDEDGYARGAWDWSMLWKRVPLTP-QEKRLRKTKTEPYRSPA--MAGGLFAIEREFF 399 +GG DE G A+ D+ L K+ P E+ L++ K R P + GLF ER+F Sbjct: 33 EGGVDEQGRAQNI-DYDKLIKQFGTKPVNEETLKRFKQVTGREPHHFLRKGLFFSERDFT 91 Query: 400 FELGLYDPG 408 L LY+ G Sbjct: 92 KILDLYEQG 100 >3LKZ-A nrPDB Length = 321 Score = 31.2 bits (69), Expect = 1.5, Method: Compositional matrix adjust. Identities = 13/49 (26%), Positives = 26/49 (53%), Gaps = 2/49 (4%) Query: 159 GPEFKQAIQ--ASIKEFGFNMVASDMISLDRSVNDLRQEECKYWHYDEN 205 GP++++ + + + G ++ SD + + LR+E WH+DEN Sbjct: 272 GPQYEEDVNLGSGTRAVGKPLLNSDTSKIKNRIERLRREYSSTWHHDEN 320 >4ZFY-B nrPDB Length = 261 Score = 30.8 bits (68), Expect = 1.9, Method: Compositional matrix adjust. Identities = 19/62 (30%), Positives = 31/62 (50%), Gaps = 5/62 (8%) Query: 590 ADGSKVMITHCNLNEFKEWQYFKNLHRFTHIPSGKCLDRSEVL--HQVFISNCDSSKTTQ 647 ADGS+V++ C + ++W ++ + T GKCL S + V I+NCD + Sbjct: 29 ADGSRVILYPCGQQQNQQWTFYPD---NTIRSLGKCLATSALSSGSNVVITNCDYLRYDD 85 Query: 648 KW 649 W Sbjct: 86 GW 87 >1MJF-A nrPDB Length = 281 Score = 30.8 bits (68), Expect = 2.1, Method: Compositional matrix adjust. Identities = 21/69 (30%), Positives = 35/69 (50%), Gaps = 4/69 (5%) Query: 121 TYHDPVLRPGILGNFEPKEPEPPGVVGGPGEKAKPLVLGPEFKQAIQASIKEFGFNMVAS 180 +YH+P++ P +L + +PK G GG G + VL + + I I E MV+ Sbjct: 60 SYHEPLVHPAMLAHPKPKRVLVIG--GGDGGTVRE-VLQHDVDEVIMVEIDE-DVIMVSK 115 Query: 181 DMISLDRSV 189 D+I +D + Sbjct: 116 DLIKIDNGL 124 >5C5V-A nrPDB Length = 342 Score = 30.8 bits (68), Expect = 2.1, Method: Compositional matrix adjust. Identities = 25/93 (26%), Positives = 40/93 (43%), Gaps = 19/93 (20%) Query: 203 DENLLTSSVVIVFHNEGWSTLMRTVHSVIKRTP----------RKY-------LAEIVLI 245 DE + VV + HN+ M+ +H V K P R Y + Sbjct: 251 DEGKMDWKVVCISHNDPICRFMKDIHDVPKFLPGCLDAIREWFRVYKICQGGEASHFAFD 310 Query: 246 DDFSNKEHLKEKLDEYIKLWNGLVKVFRNERRE 278 +F +KE+ + +DE +W+ L+KV N+R E Sbjct: 311 GEFKDKEYAMKVIDESHNMWHNLLKV--NKRGE 341 >1NYR-A nrPDB Length = 645 Score = 29.6 bits (65), Expect = 4.1, Method: Compositional matrix adjust. Identities = 22/90 (24%), Positives = 39/90 (43%), Gaps = 2/90 (2%) Query: 418 EISYKIWQCGGKLLFVPCSRVGHIYRLEGWQGNPPPIYVGSSPTLKNYVRVVEVWWDEYK 477 E+ +I + G + V + R+ G N I+V + + RVV + D YK Sbjct: 352 ELPIRIAELGTMHRYEASGAVSGLQRVRGMTLNDSHIFVRPDQIKEEFKRVVNMIIDVYK 411 Query: 478 DYFYASRPESQALPYGDISELKKFREDHNC 507 D+ + S L Y D + +K+ +D + Sbjct: 412 DFGFEDY--SFRLSYRDPEDKEKYFDDDDM 439 >5VAT-A nrPDB Length = 543 Score = 29.6 bits (65), Expect = 4.7, Method: Compositional matrix adjust. Identities = 17/65 (26%), Positives = 29/65 (44%) Query: 549 MGKTNGGFVELGPCHRMGGNQLFRINEANQLMQYDQCLTKGADGSKVMITHCNLNEFKEW 608 + K+ GG +L + MG + IN+ N+L Q G G T+CN+ W Sbjct: 471 LAKSTGGEYQLMRLYAMGADAWLLINQFNELRQVPGYRLSGLTGILSADTNCNVERDMTW 530 Query: 609 QYFKN 613 +++ Sbjct: 531 YQYQD 535 >2VSU-C nrPDB Length = 275 Score = 28.9 bits (63), Expect = 8.2, Method: Compositional matrix adjust. Identities = 14/45 (31%), Positives = 26/45 (57%), Gaps = 1/45 (2%) Query: 465 YVRVVEVWWDEYKDYFYASRPESQALPYGDISE-LKKFREDHNCK 508 + R E+ W++ +DY YA +S+ L G + +K+F +D + K Sbjct: 223 FKRCRELTWEQNEDYLYAKLDQSRLLDTGGREQGMKQFLDDKSIK 267 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 6IWR-A nrPDB 1007 0.0 2D7R-A nrPDB 730 0.0 5NQA-A nrPDB 709 0.0 5AJO-A nrPDB 671 0.0 2Z87-A nrPDB 263 2e-70 1IT0-A nrPDB 122 7e-28 Sequences not found previously or not previously below threshold: 3WN1-A nrPDB 96 4e-20 3A22-A nrPDB 82 9e-16 1HWM-B nrPDB 63 3e-10 3CAH-A nrPDB 56 4e-08 1RZO-B nrPDB 56 6e-08 3RTJ-B nrPDB 56 8e-08 2VLC-A nrPDB 55 1e-07 2Z49-A nrPDB 54 2e-07 2Q3N-B nrPDB 50 3e-06 1GGP-B nrPDB 47 2e-05 1ABR-B nrPDB 47 2e-05 5MLZ-A nrPDB 45 7e-05 6HNQ-B nrPDB 45 7e-05 4ZFY-B nrPDB 45 1e-04 5EKE-A nrPDB 44 1e-04 3D7W-B nrPDB 44 2e-04 5Y97-C nrPDB 42 7e-04 1YF8-B nrPDB 42 9e-04 2MLL-B nrPDB 42 0.001 5TZ8-A nrPDB 37 0.026 4IYB-A nrPDB 37 0.027 5C2I-A nrPDB 33 0.44 5OQM-f nrPDB 33 0.53 3O44-A nrPDB 33 0.56 1XEZ-A nrPDB 33 0.56 5HK8-A nrPDB 32 0.74 3VT2-A nrPDB 32 0.95 3ZIF-A nrPDB 32 0.96 4DND-A nrPDB 30 2.3 2DM9-A nrPDB 30 2.5 3L7K-A nrPDB 30 2.7 5Z9O-A nrPDB 30 3.2 2B5D-X nrPDB 30 4.2 5DM3-A nrPDB 30 4.7 2FTC-A nrPDB 29 5.9 4B3K-A nrPDB 29 6.7 >6IWR-A nrPDB Length = 597 Score = 1007 bits (2604), Expect = 0.0, Method: Composition-based stats. Identities = 597/597 (100%), Positives = 597/597 (100%) Query: 61 PGEDRFKPVVPWPHVEGVEVDLESIRRINKAKNEQEHHAGGDSQKDIMQRQYLTFKPQTF 120 PGEDRFKPVVPWPHVEGVEVDLESIRRINKAKNEQEHHAGGDSQKDIMQRQYLTFKPQTF Sbjct: 1 PGEDRFKPVVPWPHVEGVEVDLESIRRINKAKNEQEHHAGGDSQKDIMQRQYLTFKPQTF 60 Query: 121 TYHDPVLRPGILGNFEPKEPEPPGVVGGPGEKAKPLVLGPEFKQAIQASIKEFGFNMVAS 180 TYHDPVLRPGILGNFEPKEPEPPGVVGGPGEKAKPLVLGPEFKQAIQASIKEFGFNMVAS Sbjct: 61 TYHDPVLRPGILGNFEPKEPEPPGVVGGPGEKAKPLVLGPEFKQAIQASIKEFGFNMVAS 120 Query: 181 DMISLDRSVNDLRQEECKYWHYDENLLTSSVVIVFHNEGWSTLMRTVHSVIKRTPRKYLA 240 DMISLDRSVNDLRQEECKYWHYDENLLTSSVVIVFHNEGWSTLMRTVHSVIKRTPRKYLA Sbjct: 121 DMISLDRSVNDLRQEECKYWHYDENLLTSSVVIVFHNEGWSTLMRTVHSVIKRTPRKYLA 180 Query: 241 EIVLIDDFSNKEHLKEKLDEYIKLWNGLVKVFRNERREGLIQARSIGAQKAKLGQVLIYL 300 EIVLIDDFSNKEHLKEKLDEYIKLWNGLVKVFRNERREGLIQARSIGAQKAKLGQVLIYL Sbjct: 181 EIVLIDDFSNKEHLKEKLDEYIKLWNGLVKVFRNERREGLIQARSIGAQKAKLGQVLIYL 240 Query: 301 DAHCEVAVNWYAPLVAPISKDRTICTVPLIDVINGNTYEIIPQGGGDEDGYARGAWDWSM 360 DAHCEVAVNWYAPLVAPISKDRTICTVPLIDVINGNTYEIIPQGGGDEDGYARGAWDWSM Sbjct: 241 DAHCEVAVNWYAPLVAPISKDRTICTVPLIDVINGNTYEIIPQGGGDEDGYARGAWDWSM 300 Query: 361 LWKRVPLTPQEKRLRKTKTEPYRSPAMAGGLFAIEREFFFELGLYDPGLQIWGGENFEIS 420 LWKRVPLTPQEKRLRKTKTEPYRSPAMAGGLFAIEREFFFELGLYDPGLQIWGGENFEIS Sbjct: 301 LWKRVPLTPQEKRLRKTKTEPYRSPAMAGGLFAIEREFFFELGLYDPGLQIWGGENFEIS 360 Query: 421 YKIWQCGGKLLFVPCSRVGHIYRLEGWQGNPPPIYVGSSPTLKNYVRVVEVWWDEYKDYF 480 YKIWQCGGKLLFVPCSRVGHIYRLEGWQGNPPPIYVGSSPTLKNYVRVVEVWWDEYKDYF Sbjct: 361 YKIWQCGGKLLFVPCSRVGHIYRLEGWQGNPPPIYVGSSPTLKNYVRVVEVWWDEYKDYF 420 Query: 481 YASRPESQALPYGDISELKKFREDHNCKSFKWFMEEIAYDITSHYPLPPKNVDWGEIRGF 540 YASRPESQALPYGDISELKKFREDHNCKSFKWFMEEIAYDITSHYPLPPKNVDWGEIRGF Sbjct: 421 YASRPESQALPYGDISELKKFREDHNCKSFKWFMEEIAYDITSHYPLPPKNVDWGEIRGF 480 Query: 541 ETAYCIDSMGKTNGGFVELGPCHRMGGNQLFRINEANQLMQYDQCLTKGADGSKVMITHC 600 ETAYCIDSMGKTNGGFVELGPCHRMGGNQLFRINEANQLMQYDQCLTKGADGSKVMITHC Sbjct: 481 ETAYCIDSMGKTNGGFVELGPCHRMGGNQLFRINEANQLMQYDQCLTKGADGSKVMITHC 540 Query: 601 NLNEFKEWQYFKNLHRFTHIPSGKCLDRSEVLHQVFISNCDSSKTTQKWEMNNIHSV 657 NLNEFKEWQYFKNLHRFTHIPSGKCLDRSEVLHQVFISNCDSSKTTQKWEMNNIHSV Sbjct: 541 NLNEFKEWQYFKNLHRFTHIPSGKCLDRSEVLHQVFISNCDSSKTTQKWEMNNIHSV 597 >2D7R-A nrPDB Length = 570 Score = 730 bits (1884), Expect = 0.0, Method: Composition-based stats. Identities = 216/524 (41%), Positives = 313/524 (59%), Gaps = 30/524 (5%) Query: 148 GPGEKAKPLVLGPEFKQAIQASIKEFGFNMVASDMISLDRSVNDLRQEECKYWHYDENLL 207 G GE+ +P + + + + +E GFN+ SD ISL+RS+ D+R C Y E L Sbjct: 55 GNGEQGRPYPMTD--AERVDQAYRENGFNIYVSDKISLNRSLPDIRHPNCNSKRYLETLP 112 Query: 208 TSSVVIVFHNEGWSTLMRTVHSVIKRTPRKYLAEIVLIDDFSNKEHLKEKLDEYIKLWNG 267 +S++I FHNEGWS+L+RTVHSV+ R+P + +AEIVL+DDFS++EHLK+ L++Y+ L+ Sbjct: 113 NTSIIIPFHNEGWSSLLRTVHSVLNRSPPELVAEIVLVDDFSDREHLKKPLEDYMALFPS 172 Query: 268 LVKVFRNERREGLIQARSIGAQKAKLGQVLIYLDAHCEVAVNWYAPLVAPISKDRTICTV 327 V++ R ++REGLI+ R +GA A G V+ +LD+HCE VNW PL+ I+++R Sbjct: 173 -VRILRTKKREGLIRTRMLGASVAT-GDVITFLDSHCEANVNWLPPLLDRIARNRKTIVC 230 Query: 328 PLIDVINGNTYEIIPQGGGDEDGYARGAWDWSMLWKRVPLTPQEKRLRKTKTEPYRSPAM 387 P+IDVI+ + + Q G RGA+DW M +KR+P+ P+ + + ++P+ SP M Sbjct: 231 PMIDVIDHDDFRYETQAG----DAMRGAFDWEMYYKRIPIPPELQ--KADPSDPFESPVM 284 Query: 388 AGGLFAIEREFFFELGLYDPGLQIWGGENFEISYKIWQCGGKLLFVPCSRVGHIYRLEGW 447 AGGLFA++R++F+ELG YDPGL+IWGGE +EIS+K+W CGG++ +PCSRVGHIYR Sbjct: 285 AGGLFAVDRKWFWELGGYDPGLEIWGGEQYEISFKVWMCGGRMEDIPCSRVGHIYR---- 340 Query: 448 QGNPPPIYVGSSPTLKNYVRVVEVWWDEYKDYFYASRPESQALPYGDISELKKFREDHNC 507 + P + G S +N RV EVW DEY +Y Y RPE + L GD++ KK R NC Sbjct: 341 KYVPYKVPAGVS-LARNLKRVAEVWMDEYAEYIYQRRPEYRHLSAGDVAVQKKLRSSLNC 399 Query: 508 KSFKWFMEEIAYDITSHY-PLPPKNVDWGEIRGFETAYCIDSMGKTNGGFVELGPCHRMG 566 KSFKWFM +IA+D+ Y P+ P WGEIR T C D+ G + L C R Sbjct: 400 KSFKWFMTKIAWDLPKFYPPVEPPAAAWGEIRNVGTGLCADTKHGALGSPLRLEGCVRGR 459 Query: 567 GN------QLFRINEANQLMQYDQ------CLTKGADGSKVMITHC-NLNEFKEWQYFKN 613 G Q+F + D C + S V + C ++ + W+Y K Sbjct: 460 GEAAWNNMQVFTFTWREDIRPGDPQHTKKFCFDAISHTSPVTLYDCHSMKGNQLWKYRK- 518 Query: 614 LHRFTHIPSGKCLDRSEVLHQVFISNCDSSKTTQKWEMNNIHSV 657 H SG C+D SE H++F++ C+ S TQ+W + +S Sbjct: 519 DKTLYHPVSGSCMDCSESDHRIFMNTCNPSSLTQQWLFEHTNST 562 >5NQA-A nrPDB Length = 578 Score = 709 bits (1831), Expect = 0.0, Method: Composition-based stats. Identities = 193/535 (36%), Positives = 278/535 (51%), Gaps = 38/535 (7%) Query: 137 PKEPEPPGVVGGPGE--KAKPLVLGPEFKQAIQASIKEFGFNMVASDMISLDRSVNDLRQ 194 P +PP GE KA L L + + + I+ + N+ SD ISL R + D R Sbjct: 62 PLYKKPPADSRALGEWGKASKLQLNEDELKQQEELIERYAINIYLSDRISLHRHIEDKRM 121 Query: 195 EECKYWHYD-ENLLTSSVVIVFHNEGWSTLMRTVHSVIKRTPRKYLAEIVLIDDFSNKEH 253 ECK ++ L T+SV+I F+NE WSTL+RT+HSV++ +P L EI+L+DD S++ + Sbjct: 122 YECKSQKFNYRTLPTTSVIIAFYNEAWSTLLRTIHSVLETSPAVLLKEIILVDDLSDRVY 181 Query: 254 LKEKLDEYIKLWNGLVKVFRNERREGLIQARSIGAQKAKLGQVLIYLDAHCEVAVNWYAP 313 LK +L+ YI + V++ R +REGL++AR IGA A G VL +LD HCE W P Sbjct: 182 LKTQLETYISNLDR-VRLIRTNKREGLVRARLIGATFAT-GDVLTFLDCHCECNSGWLEP 239 Query: 314 LVAPISKDRTICTVPLIDVINGNTYEIIPQGGGDEDGYARGAWDWSMLWKRVPLTPQEKR 373 L+ I +D T P+ID I+ NT+E Q G G +DW + ++ + QE+ Sbjct: 240 LLERIGRDETAVVCPVIDTIDWNTFEFYMQIGEP----MIGGFDWRLTFQWHSVPKQERD 295 Query: 374 LRKTKTEPYRSPAMAGGLFAIEREFFFELGLYDPGLQIWGGENFEISYKIWQCGGKLLFV 433 R ++ +P RSP MAGGLFA+ +++F LG YD G+++WGGEN E+S+++WQCGGKL Sbjct: 296 RRISRIDPIRSPTMAGGLFAVSKKYFQYLGTYDTGMEVWGGENLELSFRVWQCGGKLEIH 355 Query: 434 PCSRVGHIYRLEGWQGNPPPIYVGSSPTLKNYVRVVEVWWDEYKDYFYASRPESQALPYG 493 PCS VGH++ P L+N R EVW DEYK++FY P ++ YG Sbjct: 356 PCSHVGHVF--------PKRAPYARPNFLQNTARAAEVWMDEYKEHFYNRNPPARKEAYG 407 Query: 494 DISELKKFREDHNCKSFKWFMEEIAYDITSHYPLPPKNVDW-GEIRGFE-TAYCIDSMGK 551 DISE K RE CKSF W+++ + ++ +P W G IR ++ C+D Sbjct: 408 DISERKLLRERLRCKSFDWYLKNVFPNLH----VPEDRPGWHGAIRSRGISSECLDYNSP 463 Query: 552 TN---GGFVELGPCHRMGGNQLFRINEANQLM---QYDQCLTKGADGSKVMITHCNLNEF 605 N G + L CH GGNQ F ++ + C + V + +C + F Sbjct: 464 DNNPTGANLSLFGCHGQGGNQFFEYTSNKEIRFNSVTELCAEVPEQKNYVGMQNCPKDGF 523 Query: 606 KE-----WQYFKNLHRFTHIPSGKCLD---RSEVLHQVFISNCDSSKTTQKWEMN 652 W +FK H SG CL E V + CD+ Q W Sbjct: 524 PVPANIIW-HFKEDGTIFHPHSGLCLSAYRTPEGRPDVQMRTCDALDKNQIWSFE 577 >5AJO-A nrPDB Length = 571 Score = 671 bits (1732), Expect = 0.0, Method: Composition-based stats. Identities = 181/524 (34%), Positives = 301/524 (57%), Gaps = 32/524 (6%) Query: 136 EPKEPEPPGVVGGPGEKAKPLVLGPEFKQAIQASIKEFGFNMVASDMISLDRSVNDLRQE 195 + E PPG V P + V G + Q FN V SD + +DR++ D R + Sbjct: 66 QSMETLPPGKVRWPDFNQEAYVGGTMVRSG-QDPYARNKFNQVESDKLRMDRAIPDTRHD 124 Query: 196 ECKYWHYDENLLTSSVVIVFHNEGWSTLMRTVHSVIKRTPRKYLAEIVLIDDFSNKEHLK 255 +C+ + +L +SVVI FHNE S L+RTV SV+K++P + EI+L+DD+SN Sbjct: 125 QCQRKQWRVDLPATSVVITFHNEARSALLRTVVSVLKKSPPHLIKEIILVDDYSNDPEDG 184 Query: 256 EKLDEYIKLWNGLVKVFRNERREGLIQARSIGAQKAKLGQVLIYLDAHCEVAVNWYAPLV 315 L + K V+V RN+RREGL+++R GA A+ +VL +LD+HCE +W PL+ Sbjct: 185 ALLGKIEK-----VRVLRNDRREGLMRSRVRGADAAQ-AKVLTFLDSHCECNEHWLEPLL 238 Query: 316 APISKDRTICTVPLIDVINGNTYEIIPQGGGDEDGYARGAWDWSMLWKRVPLTPQEKRLR 375 +++DRT P+IDVIN + ++ + G D +G +DW++++K +TP+++R R Sbjct: 239 ERVAEDRTRVVSPIIDVINMDNFQYV---GASAD--LKGGFDWNLVFKWDYMTPEQRRSR 293 Query: 376 K-TKTEPYRSPAMAGGLFAIEREFFFELGLYDPGLQIWGGENFEISYKIWQCGGKLLFVP 434 + P ++P +AGGLF +++ +F ELG YD + +WGGEN EIS+++WQCGG L +P Sbjct: 294 QGNPVAPIKTPMIAGGLFVMDKFYFEELGKYDMMMDVWGGENLEISFRVWQCGGSLEIIP 353 Query: 435 CSRVGHIYRLEGWQGNPPPIYVGSSPTL--KNYVRVVEVWWDEYKDYFYASRPESQALPY 492 CSRVGH++R + P + G S T+ +N R EVW DEYK+++YA+ P ++ +PY Sbjct: 354 CSRVGHVFRKQH-----PYTFPGGSGTVFARNTRRAAEVWMDEYKNFYYAAVPSARNVPY 408 Query: 493 GDISELKKFREDHNCKSFKWFMEEIAYDITSHYPLPP-KNVDWGEIRGFETAYCIDSMGK 551 G+I + R+ +CK FKW++E + ++ +P +++ +G ++ + C+D++G Sbjct: 409 GNIQSRLELRKKLSCKPFKWYLENVYPELR----VPDHQDIAFGALQ--QGTNCLDTLGH 462 Query: 552 TNGGFVELGPCHRMGGNQLFRINEANQLMQYDQCLT--KGADGSKVMITHCNLNEF-KEW 608 G V + CH GGNQ + + + + D CLT A GS + + C ++ ++W Sbjct: 463 FADGVVGVYECHNAGGNQEWALTKEKSVKHMDLCLTVVDRAPGSLIKLQGCREDDSRQKW 522 Query: 609 QYFKNLHRFTHIPSGKCLD-RSEVLHQVFISNCDSSKTTQKWEM 651 + + + H+ S CLD R+ + + C + +Q+W+ Sbjct: 523 EQIEGNSKLRHVGSNLCLDSRTAKSGGLSVEVCGPA-LSQQWKF 565 >2Z87-A nrPDB Length = 624 Score = 263 bits (672), Expect = 2e-70, Method: Composition-based stats. Identities = 53/239 (22%), Positives = 102/239 (42%), Gaps = 23/239 (9%) Query: 203 DENLLTSSVVIVFHNEGWSTLMRTVHSVIKRTPRKYLAEIVLIDDFSNKEHLKEKLDEYI 262 + L+ + IV + ++ + + Y E+++ DD S KE+++E + E+ Sbjct: 86 RKQLIIDGLSIVIPTYNRAKILAITLACLCNQKTIYDYEVIVADDGS-KENIEEIVREFE 144 Query: 263 KLWNGLVKVFRNERREGLIQARSIGAQKAKLGQVLIYLDAHCEVAVN--WYAPLVAPISK 320 L N + V + + L R++G + AK V I LD C++A N W + ++ Sbjct: 145 SLLN-IKYVRQKDYGYQLCAVRNLGLRAAKYNYVAI-LD--CDMAPNPLWVQSYMELLAV 200 Query: 321 DRTICTVPLIDVINGNTYEI------------IPQGGGDEDGYARGAWDWSMLWKRVPLT 368 D + + I+ + + IP+ + + + S+ W R+ Sbjct: 201 DDNVALIGPRKYIDTSKHTYLDFLSQKSLINEIPEIITNNQVAGKVEQNKSVDW-RIEHF 259 Query: 369 PQEKRLRKTKTEPYRSPAMAGGLFAIEREFFFELGLYDPGLQIWGGENFEISYKIWQCG 427 LR T P+R +GG A +++ F G +D WGGE+ E Y++++ G Sbjct: 260 KNTDNLRLCNT-PFR--FFSGGNVAFAKKWLFRAGWFDEEFTHWGGEDNEFGYRLYREG 315 >1IT0-A nrPDB Length = 436 Score = 122 bits (305), Expect = 7e-28, Method: Composition-based stats. Identities = 35/130 (26%), Positives = 60/130 (46%), Gaps = 12/130 (9%) Query: 529 PKNVDWGEIRGFETAYCID--SMGKTNGGFVELGPCHRMGGNQLFRINEANQLMQY-DQC 585 P G+I+G + C+D + T+G V+L CH NQ + +A +L Y D+C Sbjct: 307 PPPSGGGQIKGVGSGRCLDVPNASTTDGTQVQLYDCHSA-TNQQWTYTDAGELRVYGDKC 365 Query: 586 LTKGA--DGSKVMITHCNLNEFKEWQYFKNLHRFTHIPSGKCLDRSEVLHQ----VFISN 639 L +G+KV I C + ++W+ + + SG CLD + + + Sbjct: 366 LDAAGTGNGTKVQIYSCWGGDNQKWR-LNSDGSIVGVQSGLCLDAVGGGTANGTLIQLYS 424 Query: 640 CDSSKTTQKW 649 C S+ + Q+W Sbjct: 425 C-SNGSNQRW 433 >3WN1-A nrPDB Length = 438 Score = 96.0 bits (237), Expect = 4e-20, Method: Composition-based stats. Identities = 32/129 (24%), Positives = 55/129 (42%), Gaps = 14/129 (10%) Query: 532 VDWGEIRGFETAYCIDSMGK--TNGGFVELGPCHRMGGNQLFRINEANQLMQY-DQCLTK 588 G +RG + C+D +G +G ++L C G NQ + + +L Y D+CL Sbjct: 1 AGSGALRGAGSNRCLDVLGGSQDDGALLQLYDCW-GGTNQQWTSTDTGRLTVYGDKCLDV 59 Query: 589 G----ADGSKVMITHCNLNEFKEWQYFKNLHRFTHIPSGKCLDR----SEVLHQVFISNC 640 A G++V I C+ ++W+ + + SG CL+ + V + C Sbjct: 60 PGHATAPGTRVQIWSCSGGANQQWR-VNSDGTVVGVESGLCLEAAGAGTANGTAVQLWTC 118 Query: 641 DSSKTTQKW 649 + QKW Sbjct: 119 NGGG-NQKW 126 >3A22-A nrPDB Length = 614 Score = 81.7 bits (200), Expect = 9e-16, Method: Composition-based stats. Identities = 36/135 (26%), Positives = 59/135 (43%), Gaps = 16/135 (11%) Query: 526 PLPPKNVDWGEIRGFETAYCID--SMGKTNGGFVELGPCHRMGGNQLFRINEANQLMQY- 582 PLP N + G ++ C D + TNG EL C G NQ + +L+ Y Sbjct: 482 PLPGTNGAL--VTGKQSGRCADIYNNTITNGTQAELWDC-NGGPNQSWTYTSRKELVLYG 538 Query: 583 DQCLTK----GADGSKVMITHCNLNEFKEWQYFKNLHRFTHIPSGKCLD----RSEVLHQ 634 ++CL +G+KV+I CN ++W + T++ +G CLD + Sbjct: 539 NKCLDAYNLGTTNGTKVVIWDCNGQANQKWN-INSDGTITNVNAGLCLDAYNAATANGTS 597 Query: 635 VFISNCDSSKTTQKW 649 + + +C + QKW Sbjct: 598 LVLWSCGTGD-NQKW 611 >1HWM-B nrPDB Length = 266 Score = 63.2 bits (152), Expect = 3e-10, Method: Composition-based stats. Identities = 24/120 (20%), Positives = 46/120 (38%), Gaps = 13/120 (10%) Query: 543 AYCIDSMGK--TNGGFVELGPCHRMGGNQLFRINEANQLMQYDQCLTKGA--DGSKVMIT 598 C+D T+G ++L PC NQ + + +C+T GS +MIT Sbjct: 20 GLCVDVRNGYDTDGTPIQLWPCGTQR-NQQWTFYNDKTIRSMGKCMTANGLNSGSYIMIT 78 Query: 599 HCN--LNEFKEWQYFKNLHRFTHIPSGKCLDRSEVLHQVFI---SNCDSSKTTQKWEMNN 653 C+ + +W+ + SG + + + +N ++ Q W ++N Sbjct: 79 DCSTAAEDATKWEVLI-DGSIINPSSGLVMTAPSGASRTTLLLENNIHAAS--QGWTVSN 135 Score = 36.6 bits (83), Expect = 0.035, Method: Composition-based stats. Identities = 27/175 (15%), Positives = 53/175 (30%), Gaps = 20/175 (11%) Query: 499 KKFREDHNCKSFKWFMEEIAYDITSHYPLPPKNVDW-----GEIRGFETAYCIDSMGKTN 553 K R C + IT W G I + + + + Sbjct: 55 KTIRSMGKCMTANGLNSGSYIMITDCSTAAEDATKWEVLIDGSIINPSSGLVMTAPSGAS 114 Query: 554 GGFVELGPCHRMGGNQLFRINEANQLMQY--------DQCLTKGADGSKVMITHCNLNE- 604 + L +Q + + +N + + CL + + V + C++ Sbjct: 115 RTTLLLENNIHA-ASQGWTV--SNDVQPIATLIVGYNEMCLQANGENNNVWMEDCDVTSV 171 Query: 605 FKEWQYFKNLHRFTHIPSGKCLDRSE--VLHQVFISNCDSSKTTQKWEMNNIHSV 657 ++W F + + G C+ + + I C TQ+W N+ SV Sbjct: 172 QQQWALFDDRTIRVNNSRGLCVTSNGYVSKDLIVIRKCQGLA-TQRWFFNSDGSV 225 >3CAH-A nrPDB Length = 258 Score = 56.3 bits (134), Expect = 4e-08, Method: Composition-based stats. Identities = 21/118 (17%), Positives = 46/118 (38%), Gaps = 9/118 (7%) Query: 543 AYCIDSMGK--TNGGFVELGPCHRMGGNQLFRINEANQLMQYDQCLTKGA--DGSKVMIT 598 C+D T+G ++L PC NQ + + + + +C+T +GS ++I Sbjct: 12 GLCVDVRNGYDTDGTPLQLWPCGTQR-NQRWTFDSDDTIRSMGKCMTANGLNNGSNIVIF 70 Query: 599 HCN--LNEFKEWQYFKNLHRFTHIPSGKCLDRSEVLHQ-VFISNCDSSKTTQKWEMNN 653 +C+ +W+ + SG + + + + + +Q W + N Sbjct: 71 NCSTAAENAIKWE-VPIDGSIINPSSGLVMTAPRAASRTILLLEDNIYAASQGWTVTN 127 >1RZO-B nrPDB Length = 262 Score = 55.9 bits (133), Expect = 6e-08, Method: Composition-based stats. Identities = 25/116 (21%), Positives = 38/116 (32%), Gaps = 13/116 (11%) Query: 543 AYCIDSMGKTNGGFVELGPCHRMGGNQLFRINEANQLMQY---DQCLTKGAD--GSKVMI 597 C+ + N G V L C Q + + + D CLT A+ G+ V I Sbjct: 149 GMCL----QANSGKVWLEDCTSEKAEQQWALYADGSIRPQQNRDNCLTTDANIKGTVVKI 204 Query: 598 THC-NLNEFKEWQYFKNLHRFTHIPSGKCLDRSEVLHQVFISNCDS--SKTTQKWE 650 C + + W FKN ++ +G LD + Q W Sbjct: 205 LSCGPASSGQRW-MFKNDGTILNLYNGLVLDVRRSDPSLKQIIVHPFHGNLNQIWL 259 Score = 52.0 bits (123), Expect = 8e-07, Method: Composition-based stats. Identities = 26/126 (20%), Positives = 50/126 (39%), Gaps = 10/126 (7%) Query: 537 IRGFE-TAYCIDSMGK--TNGGFVELGPCH-RMGGNQLFRINEANQLMQYDQCLT--KGA 590 +R C+D G+ +G ++L PC NQL+ + + + + +CLT K + Sbjct: 11 VRIVGRNGLCVDVTGEEFFDGNPIQLWPCKSNTDWNQLWTLRKDSTIRSNGKCLTISKSS 70 Query: 591 DGSKVMITHCNLN--EFKEWQYFKNLHRFTHIPSGKCLDRSEVLHQVFIS-NCDSSKTTQ 647 +V+I +C+ WQ + + SG L + ++ + +Q Sbjct: 71 PRQQVVIYNCSTATVGATRWQ-IWDNRTIINPRSGLVLAATSGNSGTKLTVQTNIYAVSQ 129 Query: 648 KWEMNN 653 W N Sbjct: 130 GWLPTN 135 Score = 31.6 bits (70), Expect = 1.1, Method: Composition-based stats. Identities = 16/75 (21%), Positives = 28/75 (37%), Gaps = 5/75 (6%) Query: 582 YDQCLTKGADGSKVMITHC-NLNEFKEWQYFKNLHRFTHIPSGKCLDRSEVLHQ--VFIS 638 Y CL A+ KV + C + ++W + + CL + V I Sbjct: 148 YGMCLQ--ANSGKVWLEDCTSEKAEQQWALYADGSIRPQQNRDNCLTTDANIKGTVVKIL 205 Query: 639 NCDSSKTTQKWEMNN 653 +C + + Q+W N Sbjct: 206 SCGPASSGQRWMFKN 220 >3RTJ-B nrPDB Length = 262 Score = 55.5 bits (132), Expect = 8e-08, Method: Composition-based stats. Identities = 23/116 (19%), Positives = 37/116 (31%), Gaps = 13/116 (11%) Query: 543 AYCIDSMGKTNGGFVELGPCHRMGGNQLFRINEANQLMQY---DQCLTKGAD--GSKVMI 597 C+ + N G V + C Q + + + D CLT ++ + V I Sbjct: 149 GLCL----QANSGQVWIEDCSSEKAEQQWALYADGSIRPQQNRDNCLTSDSNIRETVVKI 204 Query: 598 THC-NLNEFKEWQYFKNLHRFTHIPSGKCLDRSEVLHQVFISNCDSS--KTTQKWE 650 C + + W FKN ++ SG LD + Q W Sbjct: 205 LSCGPASSGQRW-MFKNDGTILNLYSGLVLDVRASDPSLKQIILYPLHGDPNQIWL 259 Score = 53.2 bits (126), Expect = 4e-07, Method: Composition-based stats. Identities = 28/126 (22%), Positives = 44/126 (34%), Gaps = 10/126 (7%) Query: 537 IRGFE-TAYCIDSMGK--TNGGFVELGPCH-RMGGNQLFRINEANQLMQYDQCLTKGA-- 590 +R C+D NG ++L PC NQL+ + N + +CLT Sbjct: 11 VRIVGRNGLCVDVRDGRFHNGNAIQLWPCKSNTDANQLWTLKRDNTIRSNGKCLTTYGYS 70 Query: 591 DGSKVMITHCN--LNEFKEWQYFKNLHRFTHIPSGKCLDRSEVLHQVFIS-NCDSSKTTQ 647 G VMI CN + WQ + + S L + ++ + +Q Sbjct: 71 PGVYVMIYDCNTAATDATRWQ-IWDNGTIINPRSSLVLAATSGNSGTTLTVQTNIYAVSQ 129 Query: 648 KWEMNN 653 W N Sbjct: 130 GWLPTN 135 Score = 38.9 bits (89), Expect = 0.006, Method: Composition-based stats. Identities = 24/120 (20%), Positives = 45/120 (37%), Gaps = 10/120 (8%) Query: 540 FETAYCIDSMGKTNGGFVELGPCHRMGGN-QLFRINEANQLMQYDQCL----TKGADGSK 594 C+ + G + G +V + C+ + ++I + ++ L T G G+ Sbjct: 58 RSNGKCLTTYGYSPGVYVMIYDCNTAATDATRWQIWDNGTIINPRSSLVLAATSGNSGTT 117 Query: 595 VMITHCNLNEFKEWQYFKNLHRFTHIPS---GKCLDRSEVLHQVFISNCDSSKTTQKWEM 651 + + + W N F G CL + QV+I +C S K Q+W + Sbjct: 118 LTVQTNIYAVSQGWLPTNNTQPFVTTIVGLYGLCLQANSG--QVWIEDCSSEKAEQQWAL 175 Score = 32.0 bits (71), Expect = 0.86, Method: Composition-based stats. Identities = 25/167 (14%), Positives = 52/167 (31%), Gaps = 17/167 (10%) Query: 501 FREDHNCKSFKWFMEEIAYDITSHYPLPPKNVDW-----GEIRGFETAYCIDSMGKTNGG 555 R + C + + + I W G I ++ + + +G Sbjct: 57 IRSNGKCLTTYGYSPGVYVMIYDCNTAATDATRWQIWDNGTIINPRSSLVLAATSGNSGT 116 Query: 556 FVELGPCHRMGGNQLFRINEANQ------LMQYDQCLTKGADGSKVMITHCN-LNEFKEW 608 + + +Q + Q + Y CL A+ +V I C+ ++W Sbjct: 117 TLTVQTNIYAV-SQGWLPTNNTQPFVTTIVGLYGLCLQ--ANSGQVWIEDCSSEKAEQQW 173 Query: 609 QYFKNLHRFTHIPSGKCLDRSEVLHQ--VFISNCDSSKTTQKWEMNN 653 + + CL + + V I +C + + Q+W N Sbjct: 174 ALYADGSIRPQQNRDNCLTSDSNIRETVVKILSCGPASSGQRWMFKN 220 >2VLC-A nrPDB Length = 570 Score = 54.7 bits (130), Expect = 1e-07, Method: Composition-based stats. Identities = 25/107 (23%), Positives = 37/107 (34%), Gaps = 7/107 (6%) Query: 553 NGGFVELGPC-HRMGGNQLFRINEANQLMQYDQCLTKGAD--GSKVMITHC--NLNEFKE 607 NG ++L PC NQL+ + + +CLT G VMI C + Sbjct: 337 NGNPIQLWPCKQNSDVNQLWTLRRDGTIRSNGKCLTTNGYSAGDYVMIYDCRTPVTAASI 396 Query: 608 WQYFKNLHRFTHIPSGKCLDRSEVLHQVFIS-NCDSSKTTQKWEMNN 653 WQ F + S L + ++ D + Q W N Sbjct: 397 WQ-FWANGTIINPQSALVLSAESGNPRTTLTVQADIYASRQGWLAGN 442 Score = 39.3 bits (90), Expect = 0.005, Method: Composition-based stats. Identities = 21/113 (18%), Positives = 41/113 (36%), Gaps = 10/113 (8%) Query: 547 DSMGKTNGGFVELGPCHRMGGNQLFRINEANQLMQY---DQCLTKG---ADGSKV-MITH 599 D + NG + + C Q + + + + D+CLT + GS + + + Sbjct: 456 DLCMQANGDAMWVVECESSKAEQKWALYPDGSIRPHQDRDRCLTSTDNHSQGSIIIISSC 515 Query: 600 CNLNEFKEWQYFKNLHRFTHIPSGKCLDRSEVLHQVFISNCDSS--KTTQKWE 650 +E + W F N ++ +G +D + + K QKW Sbjct: 516 SPGSEGQRW-VFMNDGTILNLKNGLVMDVKGSDPSLHQIIIWPATGKPNQKWL 567 Score = 32.0 bits (71), Expect = 0.79, Method: Composition-based stats. Identities = 22/125 (17%), Positives = 45/125 (36%), Gaps = 12/125 (9%) Query: 535 GEIRGFETAYCIDSMGKTNGGFVELGPCHR-MGGNQLFRINEANQLMQYDQCL----TKG 589 G IR C+ + G + G +V + C + +++ ++ L G Sbjct: 362 GTIRS--NGKCLTTNGYSAGDYVMIYDCRTPVTAASIWQFWANGTIINPQSALVLSAESG 419 Query: 590 ADGSKVMITHCNLNEFKEWQYFKNLHRFTHIPSG---KCLDRSEVLHQVFISNCDSSKTT 646 + + + + W N F G C+ ++ +++ C+SSK Sbjct: 420 NPRTTLTVQADIYASRQGWLAGNNTEPFVTSIVGFNDLCM-QANGD-AMWVVECESSKAE 477 Query: 647 QKWEM 651 QKW + Sbjct: 478 QKWAL 482 >2Z49-A nrPDB Length = 432 Score = 54.0 bits (128), Expect = 2e-07, Method: Composition-based stats. Identities = 35/136 (25%), Positives = 54/136 (39%), Gaps = 13/136 (9%) Query: 530 KNVDWGEIRGFETAYCIDSMGKTNGGFVELGPCHRMGGNQLFRINEANQLMQYDQ--CLT 587 + +G +R ++ C+D G G V + C +Q FR E +++ CL Sbjct: 151 PELFYGRLRNEKSDLCLDVEGSDGKGNVLMYSCEDNL-DQWFRYYENGEIVNAKSGMCLD 209 Query: 588 K-GADGS-KVMITHCNLNEFKEWQ----YFKNLH-RFTHIPSGKCLDRS--EVLHQVFIS 638 G+DGS V I C+ + W Y + F + S KCLD S + V Sbjct: 210 VEGSDGSGNVGIYRCDDLRDQMWSRPNAYCNGDYCSFLNKESNKCLDVSGDQGTGDVGTW 269 Query: 639 NCDSS-KTTQKWEMNN 653 CD KW ++ Sbjct: 270 QCDGLPDQRFKWVFDD 285 Score = 44.7 bits (104), Expect = 1e-04, Method: Composition-based stats. Identities = 30/134 (22%), Positives = 51/134 (38%), Gaps = 24/134 (17%) Query: 533 DWGEIRGFETAYCIDSMGKTNGGFVELGPCHRMGGNQLFRI---NEANQLMQYDQCLTKG 589 D GE+R F++ C+D +G G + C + Q+ N+ Y C T Sbjct: 9 DIGELRSFKSKQCVDIVGNQGSGNIATYDCDGLSDQQIIICGDGTIRNEARNY--CFTPD 66 Query: 590 ADGSK-VMITHCNL----NEFKEWQY-----FKNLH-------RFTHIPSGKCLDR--SE 630 G+ VM + C L + W+ F + ++ SGKCLD S+ Sbjct: 67 GSGNANVMSSPCTLYPEIPSSQRWRQGRRKTFTDNGGIEQVATEIINLASGKCLDIEGSD 126 Query: 631 VLHQVFISNCDSSK 644 + + +C + Sbjct: 127 GTGDIGVYDCQNLD 140 >2Q3N-B nrPDB Length = 267 Score = 50.5 bits (119), Expect = 3e-06, Method: Composition-based stats. Identities = 23/96 (23%), Positives = 33/96 (34%), Gaps = 8/96 (8%) Query: 543 AYCID--SMGKTNGGFVELGPCHRM-GGNQLFRINEANQLMQYDQCLTK--GADGSKVMI 597 C+D NG + L C NQL+ + + +CLT A G+ VMI Sbjct: 23 GLCVDVSDNAYNNGNPIILWKCKDQLEVNQLWTLKSDKTIRSKGKCLTTYGYAPGNYVMI 82 Query: 598 THCNL--NEFKEWQYFKNLHRFTHIPSGKCLDRSEV 631 C+ E W + + SG L Sbjct: 83 YDCSSAVAEATYWD-IWDNGTIINPKSGLVLSAESS 117 Score = 37.0 bits (84), Expect = 0.025, Method: Composition-based stats. Identities = 13/90 (14%), Positives = 30/90 (33%), Gaps = 7/90 (7%) Query: 552 TNGGFVELGPCHRMGGNQLFRINEANQLMQY---DQCLTKGAD--GSKVMITHCNLN-EF 605 +G + L C Q + + + + CLT G+ +++ C+ Sbjct: 159 AHGNSMWLDVCDITKEEQQWAVYPDGSIRPVQNTNNCLTCEEHKQGATIVMMGCSNAWAS 218 Query: 606 KEWQYFKNLHRFTHIPSGKCLDRSEVLHQV 635 + W FK+ ++ +D + Sbjct: 219 QRW-VFKSDGTIYNLYDDMVMDVKSSDPSL 247 Score = 34.3 bits (77), Expect = 0.15, Method: Composition-based stats. Identities = 20/118 (16%), Positives = 44/118 (37%), Gaps = 10/118 (8%) Query: 540 FETAYCIDSMGKTNGGFVELGPCHRMGGN-QLFRINEANQLMQYDQCLTKGADGSKVMIT 598 C+ + G G +V + C + I + ++ L A+ S + T Sbjct: 63 RSKGKCLTTYGYAPGNYVMIYDCSSAVAEATYWDIWDNGTIINPKSGLVLSAESSSMGGT 122 Query: 599 -HCNLNEFKE---WQYFKNLHRFTHIPSG---KCLDRSEVLHQVFISNCDSSKTTQKW 649 N+++ W+ + F +G C++ + +++ CD +K Q+W Sbjct: 123 LTVQKNDYRMRQGWRTGNDTSPFVTSIAGFFKLCMEAHG--NSMWLDVCDITKEEQQW 178 Score = 32.4 bits (72), Expect = 0.66, Method: Composition-based stats. Identities = 12/81 (14%), Positives = 24/81 (29%), Gaps = 8/81 (9%) Query: 535 GEIRGFE-TAYCIDSMGKTNGGFVELGPCHRMGGNQLFRINEANQL------MQYDQCLT 587 G IR + T C+ G + + C +Q + + M D + Sbjct: 184 GSIRPVQNTNNCLTCEEHKQGATIVMMGCSNAWASQRWVFKSDGTIYNLYDDMVMDVKSS 243 Query: 588 KGADGSKVMITHCNLNEFKEW 608 + + + N + W Sbjct: 244 DPSLKQII-LWPYTGNANQMW 263 >1GGP-B nrPDB Length = 254 Score = 47.0 bits (110), Expect = 2e-05, Method: Composition-based stats. Identities = 27/120 (22%), Positives = 42/120 (35%), Gaps = 9/120 (7%) Query: 543 AYCIDSMG-KTNGGFVELGPCHRMGGNQLFRINEANQLMQYDQCL-TKGADGSKVMITHC 600 +C D G NG + L C NQL+ + + CL T A+ +K I C Sbjct: 13 GFCADVNGEGQNGAAIILKKC-AENDNQLWTLKREATIRSNGGCLTTAAAEQAKAGIYDC 71 Query: 601 NL--NEFKEWQYFKNLHRFTHIPSGKCLDR--SEVLHQVFISNCDSSKTTQKWEMNNIHS 656 E W+ + + S L + L + + +S + Q W N S Sbjct: 72 TQATAELSAWE-IADNGTIINPASSLVLSSGAANSLLDLGVQT-NSYASAQGWRTGNETS 129 Score = 40.5 bits (93), Expect = 0.003, Method: Composition-based stats. Identities = 16/103 (15%), Positives = 35/103 (33%), Gaps = 8/103 (7%) Query: 555 GFVELGPCHRMGGNQLFRINEANQLM---QYDQCLTKGADGSK--VMITHCNLNEFKEWQ 609 + + C Q + + + D CLT AD +++ C+ + W Sbjct: 150 ANLWMSECRAGKAEQQWALLTDKSIRSETNSDNCLTSAADAGPKTILLALCSGPASQRW- 208 Query: 610 YFKNLHRFTHIPSGKCLDR--SEVLHQVFISNCDSSKTTQKWE 650 F + + K +D + + I ++++ Q W Sbjct: 209 VFDDDGSILSLYDDKQMDSEGAAAAAKQIILWWNAAEPNQIWL 251 >1ABR-B nrPDB Length = 267 Score = 47.0 bits (110), Expect = 2e-05, Method: Composition-based stats. Identities = 24/96 (25%), Positives = 35/96 (36%), Gaps = 8/96 (8%) Query: 543 AYCID--SMGKTNGGFVELGPCH-RMGGNQLFRINEANQLMQYDQCLTK--GADGSKVMI 597 C+D G NG + + C R+ NQL+ + + +CLT A GS VMI Sbjct: 23 GMCVDVYDNGYHNGNRIIMWKCKDRLEENQLWTLKSDKTIRSNGKCLTTYGYAPGSYVMI 82 Query: 598 THCNL--NEFKEWQYFKNLHRFTHIPSGKCLDRSEV 631 C E W+ + + S L Sbjct: 83 YDCTSAVAEATYWE-IWDNGTIINPKSALVLSAESS 117 Score = 45.1 bits (105), Expect = 1e-04, Method: Composition-based stats. Identities = 19/112 (16%), Positives = 33/112 (29%), Gaps = 9/112 (8%) Query: 547 DSMGKTNGGFVELGPCHRMGGNQLFRINEANQLMQY---DQCLTKGAD--GSKVMITHCN 601 D + G V + C Q + + + + CLT GS +++ C+ Sbjct: 154 DLCMQAQGSNVWMADCDSNKKEQQWALYTDGSIRSVQNTNNCLTSKDHKQGSTILLMGCS 213 Query: 602 LN-EFKEWQYFKNLHRFTHIPSGKCLDRSEVLHQVFISNCDS--SKTTQKWE 650 + W FKN + +D + K Q W Sbjct: 214 NGWASQRW-VFKNDGSIYSLYDDMVMDVKGSDPSLKQIILWPYTGKPNQIWL 264 Score = 43.9 bits (102), Expect = 2e-04, Method: Composition-based stats. Identities = 21/120 (17%), Positives = 42/120 (35%), Gaps = 10/120 (8%) Query: 540 FETAYCIDSMGKTNGGFVELGPCHRMGGN-QLFRINEANQLMQYDQCL----TKGADGSK 594 C+ + G G +V + C + I + ++ L + G Sbjct: 63 RSNGKCLTTYGYAPGSYVMIYDCTSAVAEATYWEIWDNGTIINPKSALVLSAESSSMGGT 122 Query: 595 VMITHCNLNEFKEWQYFKNLHRFTHIPSG---KCLDRSEVLHQVFISNCDSSKTTQKWEM 651 + + + W+ N F SG C+ V++++CDS+K Q+W + Sbjct: 123 LTVQTNEYLMRQGWRTGNNTSPFVTSISGYSDLCMQAQGS--NVWMADCDSNKKEQQWAL 180 Score = 36.2 bits (82), Expect = 0.051, Method: Composition-based stats. Identities = 13/81 (16%), Positives = 24/81 (29%), Gaps = 8/81 (9%) Query: 535 GEIRGFE-TAYCIDSMGKTNGGFVELGPCHRMGGNQLFRINEANQL------MQYDQCLT 587 G IR + T C+ S G + L C +Q + + M D + Sbjct: 184 GSIRSVQNTNNCLTSKDHKQGSTILLMGCSNGWASQRWVFKNDGSIYSLYDDMVMDVKGS 243 Query: 588 KGADGSKVMITHCNLNEFKEW 608 + + + + W Sbjct: 244 DPSLKQII-LWPYTGKPNQIW 263 >5MLZ-A nrPDB Length = 374 Score = 45.5 bits (106), Expect = 7e-05, Method: Composition-based stats. Identities = 28/116 (24%), Positives = 44/116 (37%), Gaps = 4/116 (3%) Query: 211 VVIVFHNEGWSTLMRTVHSVIKRTPRKYLAEIVLIDDFSNKEHLKEKLDEYIKLWNGLVK 270 V ++ + + S I + EIV++DD S EK E + VK Sbjct: 25 VSVIIPTYNERENLEELFSRIDNALQGLNYEIVVVDDDSPDRTW-EKAQELSSKYP--VK 81 Query: 271 VFRNERREGLIQARSIGAQKAKLGQVLIYLDAHCEVAVNWYAPLVAPISKDRTICT 326 V R + +GL A G ++A G V + +DA + L+ I I Sbjct: 82 VIRRTKEKGLSSAVIRGFKEAS-GDVFVVMDADLQHPPEVIPKLIEAIKNGSDIAI 136 >6HNQ-B nrPDB Length = 345 Score = 45.5 bits (106), Expect = 7e-05, Method: Composition-based stats. Identities = 30/94 (31%), Positives = 49/94 (52%), Gaps = 6/94 (6%) Query: 210 SVVIVFHNEGWSTLMRTVHSVIKRTPRKYLAEIVLIDDFSNKEHLKEKLDEYIKLWNGLV 269 SV++ N G L RT+ SV+ +T + E+++IDD SN E L IK + GLV Sbjct: 23 SVIMPTFNNG-EKLHRTISSVLNQTMKSTDYELIIIDDHSNDN--GETL-NVIKKYKGLV 78 Query: 270 KVFRNERREGLIQA-RSIGAQKAKLGQVLIYLDA 302 + + ++ G R+ G + +K V +LD+ Sbjct: 79 RFKQLKKNSGNASVPRNTGLKMSKAEYVF-FLDS 111 >4ZFY-B nrPDB Length = 261 Score = 44.7 bits (104), Expect = 1e-04, Method: Composition-based stats. Identities = 24/116 (20%), Positives = 44/116 (37%), Gaps = 6/116 (5%) Query: 543 AYCIDSMG--KTNGGFVELGPCHRMGGNQLFRINEANQLMQYDQCL--TKGADGSKVMIT 598 C+D G +G V L PC NQ + N + +CL + + GS V+IT Sbjct: 18 GLCVDVYGALTADGSRVILYPC-GQQQNQQWTFYPDNTIRSLGKCLATSALSSGSNVVIT 76 Query: 599 HCNLNEFKEWQYFKNLHRFTHIPSGKCLDRSEVLHQVFIS-NCDSSKTTQKWEMNN 653 +C+ + + + + S L + + ++ + Q W + N Sbjct: 77 NCDYLRYDDGWMVSSSGTMMNKSSHLVLTANAATSRTNLTGENNVFAAKQAWRIGN 132 Score = 38.9 bits (89), Expect = 0.007, Method: Composition-based stats. Identities = 17/113 (15%), Positives = 42/113 (37%), Gaps = 11/113 (9%) Query: 545 CIDSMGKTNGGFVELGPCHRMGGNQLFRINEANQLMQY---DQCLTKGADGS--KVMITH 599 C++ N V L C + Q + + + + + C++ D S ++I Sbjct: 148 CLE--ATDNDTNVWLESCVKNKTKQYWALYSDDTIRVNNNRNLCVSSSTDSSSKLIVIRR 205 Query: 600 CNLNEFKEWQYFKNLHRFTHIPSGKCLDRSEVL---HQVFISNCDSSKTTQKW 649 C+ + + W F ++ +D ++ ++ +S+ Q+W Sbjct: 206 CDGSINQRW-VFTPQGTISNPGYEAVMDVAQNDVYLKKIVLSSATDKGNGQQW 257 >5EKE-A nrPDB Length = 341 Score = 44.3 bits (103), Expect = 1e-04, Method: Composition-based stats. Identities = 32/110 (29%), Positives = 48/110 (43%), Gaps = 7/110 (6%) Query: 210 SVVIVFHNE--GWSTLMRTVHSVIKRTPRKYLAEIVLIDDFSNKEHLKEKLDEYIKLWNG 267 S+VI +NE L + V+ TP K EI+ ++D S + LK+ +D Y N Sbjct: 29 SIVIPMYNEEDNLEHLFARLLEVL--TPLKITYEIICVNDGSKDKTLKQLIDCYQS--NR 84 Query: 268 LVKVFRNERREGLIQARSIGAQKAKLGQVLIYLDAHCEVAVNWYAPLVAP 317 +K+ R G A S G A+ G +I +DA + LV Sbjct: 85 QIKIVNLSRNFGKEIALSAGIDYAQ-GNAVIPIDADLQDPPELIHELVDK 133 >3D7W-B nrPDB Length = 265 Score = 44.3 bits (103), Expect = 2e-04, Method: Composition-based stats. Identities = 22/114 (19%), Positives = 40/114 (35%), Gaps = 11/114 (9%) Query: 544 YCIDSMGKTNGGFVELGPCHRMGGNQLFRINEANQLMQ---YDQCLTKGAD--GSKVMIT 598 C++S GG V + C NQ + + + QCLT G D + + I Sbjct: 151 LCMES----AGGSVYVETCTAGQENQRWALYGDGSIRPKQLQSQCLTNGRDSISTVINIV 206 Query: 599 HCNLNEFKEWQYFKNLHRFTHIPSGKCLDRSEVLHQVFISNCDSS--KTTQKWE 650 C+ + F N ++ +G +D ++ + + Q W Sbjct: 207 SCSAGSSGQRWVFTNEGAILNLKNGLAMDVAQANPSLQRIIIYPATGNPNQMWL 260 Score = 42.4 bits (98), Expect = 6e-04, Method: Composition-based stats. Identities = 26/108 (24%), Positives = 37/108 (34%), Gaps = 9/108 (8%) Query: 553 NGGFVELGPCHRMGG-NQLFRINEANQLMQYDQCLTKGAD--GSKVMITHCN--LNEFKE 607 +G ++L P NQL+ I + + CLT G VMI CN + E Sbjct: 31 DGNQIQLWPSKSNNDPNQLWTIKKDGTIRSNGSCLTTYGYTAGVYVMIFDCNTAVREATI 90 Query: 608 WQYFKNLHRFTHIPSGKCLDRSEVLHQVFISNCDSSKTT--QKWEMNN 653 WQ + S L S + + + T Q W N Sbjct: 91 WQ-IWGNGTIINPRSNLVLAASSGIKGTTL-TVQTLDYTLGQGWLAGN 136 Score = 36.6 bits (83), Expect = 0.039, Method: Composition-based stats. Identities = 20/137 (14%), Positives = 49/137 (35%), Gaps = 19/137 (13%) Query: 529 PKNVDW-----GEIRGFETAYCIDSMGKTNGGFVELGPCHRM-GGNQLFRINEANQLM-- 580 N W G IR + C+ + G T G +V + C+ +++I ++ Sbjct: 45 DPNQLWTIKKDGTIRSNGS--CLTTYGYTAGVYVMIFDCNTAVREATIWQIWGNGTIINP 102 Query: 581 QYDQCLTKGA--DGSKVMITHCNLNEFKEWQYFKN----LHRFTHIPSGKCLDRSEVLHQ 634 + + L + G+ + + + + W + C++ + Sbjct: 103 RSNLVLAASSGIKGTTLTVQTLDYTLGQGWLAGNDTAPRETTIYGFRD-LCMESAGG--S 159 Query: 635 VFISNCDSSKTTQKWEM 651 V++ C + + Q+W + Sbjct: 160 VYVETCTAGQENQRWAL 176 Score = 31.2 bits (69), Expect = 1.3, Method: Composition-based stats. Identities = 10/80 (12%), Positives = 25/80 (31%), Gaps = 6/80 (7%) Query: 535 GEIRGFE-TAYCIDSMGKTNGGFVELGPCHRMGGNQLFRINEANQLMQY-DQCLTKGADG 592 G IR + + C+ + + + + C Q + ++ + A Sbjct: 180 GSIRPKQLQSQCLTNGRDSISTVINIVSCSAGSSGQRWVFTNEGAILNLKNGLAMDVAQA 239 Query: 593 SK----VMITHCNLNEFKEW 608 + ++I N + W Sbjct: 240 NPSLQRIIIYPATGNPNQMW 259 >5Y97-C nrPDB Length = 264 Score = 42.0 bits (97), Expect = 7e-04, Method: Composition-based stats. Identities = 16/64 (25%), Positives = 27/64 (42%), Gaps = 5/64 (7%) Query: 543 AYCIDSMG--KTNGGFVELGPCHRMGGNQLFRINEANQLMQYDQCLTKGAD--GSKVMIT 598 A C+D G ++G + L PC NQ + + + +CL G+ V+I Sbjct: 17 ALCVDVAGALTSDGSRLILYPC-GQQVNQKWTFHSDGTVRSLGKCLATNNSKFGNLVVIY 75 Query: 599 HCNL 602 C+ Sbjct: 76 DCSK 79 Score = 41.3 bits (95), Expect = 0.002, Method: Composition-based stats. Identities = 17/117 (14%), Positives = 39/117 (33%), Gaps = 13/117 (11%) Query: 545 CIDSMGKTNGGFVELGPCHRMGGNQLFRINEANQLMQYD---QCLTKGADG----SKVMI 597 C++ + L C Q + + + D C+T + + I Sbjct: 149 CLE--ATDGNTNMWLEECVPNQREQSWALYSDGTIRVDDNRELCVTASSSTYDNWKVITI 206 Query: 598 THCNLNEFKEWQYFKNLHRFTHIPSG-KCLD--RSEVLHQVFISNCDSSKTTQKWEM 651 +C+ + + W + + + +D RS+V + I + Q+W + Sbjct: 207 LNCDGSNNQRWVFL-ADGSISTPGNQRLAMDVARSDVDLKKIILHRPHGDLNQQWVL 262 Score = 30.1 bits (66), Expect = 3.0, Method: Composition-based stats. Identities = 14/74 (18%), Positives = 25/74 (33%), Gaps = 6/74 (8%) Query: 583 DQCLTKGADGSKVMITHCNLNEFKEWQYFKNLHRFT-HIPSGKCLDRSEVLHQ----VFI 637 D CL + + + C N+ ++ + C+ S + + I Sbjct: 147 DMCLEATDGNTNMWLEECVPNQREQSWALYSDGTIRVDDNRELCVTASSSTYDNWKVITI 206 Query: 638 SNCDSSKTTQKWEM 651 NCD S Q+W Sbjct: 207 LNCDGSN-NQRWVF 219 Score = 30.1 bits (66), Expect = 3.2, Method: Composition-based stats. Identities = 11/53 (20%), Positives = 21/53 (39%), Gaps = 7/53 (13%) Query: 584 QCLTKGA----DGSKVMITHCNLNEFKEWQYFKNLHRFTHIPSGKCLDRSEVL 632 C+ DGS++++ C ++W F + + GKCL + Sbjct: 18 LCVDVAGALTSDGSRLILYPCGQQVNQKWT-FHSDGTVRSL--GKCLATNNSK 67 >1YF8-B nrPDB Length = 255 Score = 42.0 bits (97), Expect = 9e-04, Method: Composition-based stats. Identities = 26/108 (24%), Positives = 36/108 (33%), Gaps = 9/108 (8%) Query: 553 NGGFVELGPCHRMGG-NQLFRINEANQLMQYDQCLTKGAD--GSKVMITHCN--LNEFKE 607 +G ++L P NQL+ I + CLT G VMI CN + E Sbjct: 27 DGNQIQLWPSKSNNDPNQLWTIKRDGTIRSNGSCLTTYGYTAGVYVMIFDCNTAVREATI 86 Query: 608 WQYFKNLHRFTHIPSGKCLDRSEVLHQVFISNCDSSKTT--QKWEMNN 653 WQ + S L S + + + T Q W N Sbjct: 87 WQ-IWGNGTIINPRSNLALAASSGIKGTTL-TVQTLDYTLGQGWLAGN 132 Score = 30.1 bits (66), Expect = 2.8, Method: Composition-based stats. Identities = 9/77 (11%), Positives = 23/77 (29%), Gaps = 3/77 (3%) Query: 535 GEIRGFETAYCIDSMGKTNGGFVELGPCHRMGGNQLFRINEANQLMQYD--QCLTKGADG 592 G IR + + G+ + + + C Q + ++ + G Sbjct: 175 GSIRPEQNQDQCLTSGRDSVAGINIVSCSGGSSGQRWVFTNEGAILNLKNGLAMDVANPG 234 Query: 593 -SKVMITHCNLNEFKEW 608 +++I + W Sbjct: 235 LGQIIIYPATGKPNQMW 251 Score = 29.3 bits (64), Expect = 4.9, Method: Composition-based stats. Identities = 20/137 (14%), Positives = 49/137 (35%), Gaps = 20/137 (14%) Query: 529 PKNVDW-----GEIRGFETAYCIDSMGKTNGGFVELGPCHRM-GGNQLFRINEANQLM-- 580 N W G IR + C+ + G T G +V + C+ +++I ++ Sbjct: 41 DPNQLWTIKRDGTIRSNGS--CLTTYGYTAGVYVMIFDCNTAVREATIWQIWGNGTIINP 98 Query: 581 QYDQCLTKGA--DGSKVMITHCNLNEFKEWQYFKNLH----RFTHIPSGKCLDRSEVLHQ 634 + + L + G+ + + + + W + + C++ + Sbjct: 99 RSNLALAASSGIKGTTLTVQTLDYTLGQGWLAGNDTAPREVTIYGF-NDLCMESNGG--S 155 Query: 635 VFISNCDSSKTTQKWEM 651 V++ C S+ +W + Sbjct: 156 VWVETC-VSQQNDRWAL 171 >2MLL-B nrPDB Length = 255 Score = 41.6 bits (96), Expect = 0.001, Method: Composition-based stats. Identities = 25/108 (23%), Positives = 35/108 (32%), Gaps = 9/108 (8%) Query: 553 NGGFVELGPCHRMGG-NQLFRINEANQLMQYDQCLTKGAD--GSKVMITHC--NLNEFKE 607 +G ++L P NQL+ I + CLT G VMI C + E Sbjct: 27 DGNQIQLWPSKSNNDPNQLWTIKRDGTIRSNGSCLTTYGYTAGVYVMIFDCATAVGEATV 86 Query: 608 WQYFKNLHRFTHIPSGKCLDRSEVLHQVFISNCDSSKTT--QKWEMNN 653 WQ + S L S + + + T Q W N Sbjct: 87 WQ-IWGNGTIINPRSNLVLAASSGIKGTTL-TVQTLDYTLGQGWLAGN 132 Score = 33.2 bits (74), Expect = 0.40, Method: Composition-based stats. Identities = 12/78 (15%), Positives = 25/78 (32%), Gaps = 5/78 (6%) Query: 535 GEIRGFET-AYCIDSMGKTNGGFVELGPCHRMGGNQLFRINEANQLMQYD--QCLTKGAD 591 G IR + A C+ + G + V + C Q + ++ + Sbjct: 175 GSIRPEQNQAQCL-TSGGDSVAGVNIVSCSGAASGQRWVFTNEGAILNLKNGLAMDVANP 233 Query: 592 -GSKVMITHCNLNEFKEW 608 G +++I + W Sbjct: 234 GGGRIIIYPATGKPNQMW 251 Score = 32.4 bits (72), Expect = 0.60, Method: Composition-based stats. Identities = 29/180 (16%), Positives = 52/180 (28%), Gaps = 60/180 (33%) Query: 529 PKNVDW-----GEIRGFETAYCIDSMGKTNGGFVELGPCHRMGGN----QLF-------- 571 N W G IR + C+ + G T G +V + C G Q++ Sbjct: 41 DPNQLWTIKRDGTIRSNGS--CLTTYGYTAGVYVMIFDCATAVGEATVWQIWGNGTIINP 98 Query: 572 ---------------------------------RINEANQLMQY---DQCLTKGADGSKV 595 ++ Y D C+ G G V Sbjct: 99 RSNLVLAASSGIKGTTLTVQTLDYTLGQGWLAGNDTAPREVTIYGFNDLCMESG--GGSV 156 Query: 596 MITHCNLNEFKEWQYFKNLHRFTHIPS-GKCLDR-SEVLHQVFISNCDSSKTTQKWEMNN 653 + C+ + +W + + +CL + + V I +C + + Q+W N Sbjct: 157 TVETCSSGKADKWALY-GDGSIRPEQNQAQCLTSGGDSVAGVNIVSCSGAASGQRWVFTN 215 >5TZ8-A nrPDB Length = 572 Score = 37.0 bits (84), Expect = 0.026, Method: Composition-based stats. Identities = 15/92 (16%), Positives = 42/92 (45%), Gaps = 4/92 (4%) Query: 212 VIVFHNEGWSTLMRTVHSVIKRTP-RKYLAEIVLIDDFSNKEHLKEKLDEYIKLWNGLVK 270 ++ + + + + + K E+V++DD S + L+ +++Y N V Sbjct: 4 SVIVPTYNSEKYITELLNSLAKQDFPKTEFEVVVVDDCSTDQTLQ-IVEKYRNKLNLKVS 62 Query: 271 VFRNERREGLIQARSIGAQKAKLGQVLIYLDA 302 G + R++ ++A+ G+ ++++D+ Sbjct: 63 QLETNSG-GPGKPRNVALKQAE-GEFVLFVDS 92 >4IYB-A nrPDB Length = 140 Score = 37.0 bits (84), Expect = 0.027, Method: Composition-based stats. Identities = 15/72 (20%), Positives = 25/72 (34%), Gaps = 6/72 (8%) Query: 536 EIRGFETAYCIDSMGKTNGGFVELGPCHRMGGNQLFRINEANQLMQYDQCLTKGADGSKV 595 +I + ID G+ N + P H G NQ + N + L + GS + Sbjct: 11 KITNVKAGTVIDLSGEDNKSIIG-YPYHS-GKNQQWTFNWTGKAWT----LRSASSGSYL 64 Query: 596 MITHCNLNEFKE 607 I + + Sbjct: 65 GIEGTPADGTRL 76 >5C2I-A nrPDB Length = 468 Score = 32.8 bits (73), Expect = 0.44, Method: Composition-based stats. Identities = 12/57 (21%), Positives = 21/57 (36%) Query: 163 KQAIQASIKEFGFNMVASDMISLDRSVNDLRQEECKYWHYDENLLTSSVVIVFHNEG 219 + I+ FGF S + + R V R C + +D S+++ N Sbjct: 189 RNQAGQIIEHFGFVHGVSQPLFMKRDVVRERVNNCDFDKWDPKAPLDSILVEDPNGN 245 >5OQM-f nrPDB Length = 210 Score = 32.8 bits (73), Expect = 0.53, Method: Composition-based stats. Identities = 17/94 (18%), Positives = 34/94 (36%), Gaps = 3/94 (3%) Query: 191 DLRQEECKYWHYDENLLTSSVVIVFHNEGWSTLMRTVHSVIKRTPRKYLAEIVLIDDFSN 250 D R C + ++ I FH+ G T++ +S + T L+ + S+ Sbjct: 38 DFRTYRCSIKNLPADVSKLMYSITFHHHGRQTVLIKDNSAMVTTAAAADIPPALVFNGSS 97 Query: 251 K---EHLKEKLDEYIKLWNGLVKVFRNERREGLI 281 E + L + ++ + + E LI Sbjct: 98 TGVPESIDTILSSKLSNIWMQRQLIKGDAGETLI 131 >3O44-A nrPDB Length = 593 Score = 32.8 bits (73), Expect = 0.56, Method: Composition-based stats. Identities = 19/108 (17%), Positives = 38/108 (35%), Gaps = 8/108 (7%) Query: 552 TNGGFVELGPCHRMGGNQLFRINEANQLMQYD---QCLTKGADGSKVMITHCNLNEFKEW 608 G + C Q F ++ + + CL A + CN N + W Sbjct: 353 DAQGRLTANMCDSQQSAQSFIYDQLGRYVSASNTKLCLDGAA---LDALQPCNQNLTQRW 409 Query: 609 QYFKNLHRFTHIPSGKCL--DRSEVLHQVFISNCDSSKTTQKWEMNNI 654 ++ K T++ SG+ L D+ ++ S+ D+ ++ Sbjct: 410 EWRKGTDELTNVYSGESLGHDKQTGELGLYASSNDAVSLRTITAYTDV 457 >1XEZ-A nrPDB Length = 721 Score = 32.8 bits (73), Expect = 0.56, Method: Composition-based stats. Identities = 19/108 (17%), Positives = 38/108 (35%), Gaps = 8/108 (7%) Query: 552 TNGGFVELGPCHRMGGNQLFRINEANQLMQYD---QCLTKGADGSKVMITHCNLNEFKEW 608 G + C Q F ++ + + CL A + CN N + W Sbjct: 481 DAQGRLTANMCDSQQSAQSFIYDQLGRYVSASNTKLCLDGAA---LDALQPCNQNLTQRW 537 Query: 609 QYFKNLHRFTHIPSGKCL--DRSEVLHQVFISNCDSSKTTQKWEMNNI 654 ++ K T++ SG+ L D+ ++ S+ D+ ++ Sbjct: 538 EWRKGTDELTNVYSGESLGHDKQTGELGLYASSNDAVSLRTITAYTDV 585 >5HK8-A nrPDB Length = 298 Score = 32.0 bits (71), Expect = 0.74, Method: Composition-based stats. Identities = 16/75 (21%), Positives = 31/75 (41%), Gaps = 1/75 (1%) Query: 70 VPWPHVEGVEVDLESIRRINKAKNEQEHHAGGDSQKDIMQRQYLTFKP-QTFTYHDPVLR 128 +P PH+ + V E I + + G + + ++ Y + P + T +LR Sbjct: 156 IPSPHLSNIHVGEEDIWEYTYGEGTDKPPTGVLMKPEFIRHYYYSQSPLEDVTLSSKLLR 215 Query: 129 PGILGNFEPKEPEPP 143 P + F+ + PP Sbjct: 216 PAPMRAFQDLDKLPP 230 >3VT2-A nrPDB Length = 526 Score = 32.0 bits (71), Expect = 0.95, Method: Composition-based stats. Identities = 12/101 (11%), Positives = 30/101 (29%), Gaps = 13/101 (12%) Query: 521 ITSHYPLPPKNVDWGEIRGFETAYCIDSM--GKTNGGFVELGPCHRMGGNQLFRINEANQ 578 ++ + L + +I ++ +D K +GG + G NQ ++ + Sbjct: 396 LSQQWYLVDVGGGYKKIVNVKSGRALDVKDESKEDGGVLIQY-TSNGGYNQHWKFTDIGD 454 Query: 579 ------LMQYDQCLTKG----ADGSKVMITHCNLNEFKEWQ 609 + + DG + + W+ Sbjct: 455 GYYKISSRHCGKLIDVRKWSTEDGGIIQQWSDAGGTNQHWK 495 >3ZIF-A nrPDB Length = 911 Score = 32.0 bits (71), Expect = 0.96, Method: Composition-based stats. Identities = 15/104 (14%), Positives = 30/104 (28%), Gaps = 8/104 (7%) Query: 501 FREDHNCKSFKWFMEE---IAYDITSHYPLPPKNVDWGEIRGFETAYCIDSMGKTNGGFV 557 R D N +SF ++ + + LP + +W RG+ G Sbjct: 596 LRNDTNDQSFNDYLSAANMLYPIPPNATQLPIPSRNWAAFRGWSLTRLKQRETPALGSPF 655 Query: 558 ELGPCHRM-----GGNQLFRINEANQLMQYDQCLTKGADGSKVM 596 + + G +Q+D +T + + Sbjct: 656 DPYFTYSGTIPYLDGTFYLSHTFRKVAIQFDSSVTWPGNDRLLT 699 >4DND-A nrPDB Length = 130 Score = 30.5 bits (67), Expect = 2.3, Method: Composition-based stats. Identities = 13/50 (26%), Positives = 23/50 (46%), Gaps = 2/50 (4%) Query: 459 SPTLKNYVRVVEVWWDEYKDYF--YASRPESQALPYGDISELKKFREDHN 506 + L+N +R +E ++ ++ + P LP GD+ E K F E Sbjct: 69 TNELRNGLRSIEWDLEDLEETIGIVEANPGKFKLPAGDLQERKVFVERMR 118 >2DM9-A nrPDB Length = 198 Score = 30.5 bits (67), Expect = 2.5, Method: Composition-based stats. Identities = 27/76 (35%), Positives = 40/76 (52%), Gaps = 6/76 (7%) Query: 226 TVHSVIKRTPRKYLAEIVLIDDFSNKEHLKEKLDEYIKLWN-GLVKVFRNERREGLIQAR 284 + SV++ R+ E + D++ E +K L E IK N V+V NE+ GLI +R Sbjct: 82 IISSVLEEVKRRL--ETMSEDEYF--ESVKALLKEAIKELNEKKVRVMSNEKTLGLIASR 137 Query: 285 SIGAQKAKLGQVLIYL 300 I K++LG V I L Sbjct: 138 -IEEIKSELGDVSIEL 152 >3L7K-A nrPDB Length = 729 Score = 30.5 bits (67), Expect = 2.7, Method: Composition-based stats. Identities = 22/110 (20%), Positives = 49/110 (44%), Gaps = 8/110 (7%) Query: 159 GPEFKQAIQASIKEFGFNM--VASDMISLDRSVNDLRQEECKYWHY---DENLLTSSVVI 213 + K+ + +IK++ N+ + D S ++ EE + ++ D + +S I Sbjct: 42 TDQSKKLMDEAIKDYDKNIRFIDLDENSGHAHARNIALEEVETPYFMFLDADDELASYAI 101 Query: 214 VFHNE---GWSTLMRTVHSVIKRTPRKYLAEIVLIDDFSNKEHLKEKLDE 260 F+ E L+ +HS + P+ + V ++ F+ KE++ L + Sbjct: 102 TFYLEKFNNTDGLIAPIHSFTTQRPQFVDLDRVRVEYFNAKENINSFLRK 151 >5Z9O-A nrPDB Length = 399 Score = 30.1 bits (66), Expect = 3.2, Method: Composition-based stats. Identities = 11/45 (24%), Positives = 19/45 (42%), Gaps = 3/45 (6%) Query: 578 QLMQYDQCLTKGADGSKVMITHCNLNEFKEWQYFKNLHRFTHIPS 622 Q YD+ L A+ V + ++W Y ++ F H+ S Sbjct: 205 QKKIYDEGLEDVAE---VKLEDYRELGDQQWDYVTSVGMFEHVGS 246 >2B5D-X nrPDB Length = 528 Score = 29.7 bits (65), Expect = 4.2, Method: Composition-based stats. Identities = 34/198 (17%), Positives = 69/198 (34%), Gaps = 31/198 (15%) Query: 294 GQVLIYLDAHCEVAVNWYAPLVAPISKDR------TICTVPLIDVIN-GNTYEIIPQGGG 346 G++LI+L AH + P ++R T +PL+ + + + + Sbjct: 3 GKILIFLHAHL---PYVHHPEYDHFLEERWLFEAITETYIPLLMMFDEIEDFRLTMSI-T 58 Query: 347 DEDGYARGAWDWSMLWKRVPL----TPQEKRLRKTKTEPYRSPAMAGGLFAIEREFFFEL 402 + D ++R ++ R K P + + + + Sbjct: 59 PPLMEMLSSRDLQEKYERHMEKLIELANKEVERTKKEHPLKHK--------MAKFYREHF 110 Query: 403 GLYDPGLQIWGGENFEISYKIWQCGGKLLFVPCSRVGHIYRLEGWQGNPPPIYVGSSPTL 462 + + G E +K +Q GKL V C+ H + L +Q P + + + Sbjct: 111 EKILNVFRSYDGNILE-GFKKYQETGKLEIVTCNAT-HAF-LPLYQMYPEVVNAQITVGV 167 Query: 463 KNYVRVVE-----VWWDE 475 KNY + ++ +W E Sbjct: 168 KNYEKHMKKHPRGIWLAE 185 >5DM3-A nrPDB Length = 475 Score = 29.7 bits (65), Expect = 4.7, Method: Composition-based stats. Identities = 12/58 (20%), Positives = 23/58 (39%), Gaps = 7/58 (12%) Query: 400 FELGLYDPGLQIWGGENFEISYKIWQCGGKLLFVPCSRVGHIYRLEGWQGNPPPIYVG 457 F+ G + P +W +N +++ G + + + C R+ G NP G Sbjct: 338 FQKGTFAPTRTVWSVDNRTAGFRLCAEGTRAVRIEC-------RIGGSDLNPYLAMAG 388 >2FTC-A nrPDB Length = 189 Score = 29.3 bits (64), Expect = 5.9, Method: Composition-based stats. Identities = 17/70 (24%), Positives = 25/70 (35%), Gaps = 7/70 (10%) Query: 458 SSPTLKNYVRVVEVWWDEYKDYFYASRPESQALPYGDISELKKFREDHNCKSFKWFMEEI 517 + + ++W DE FY + PE + EL + R+ N K K I Sbjct: 52 GAAFAGGTSLIQKIWDDEIVADFYVAVPEI-------MPELNRLRKKLNKKYPKLSRNSI 104 Query: 518 AYDITSHYPL 527 DI L Sbjct: 105 GRDIPKMLEL 114 >4B3K-A nrPDB Length = 479 Score = 28.9 bits (63), Expect = 6.7, Method: Composition-based stats. Identities = 13/71 (18%), Positives = 24/71 (33%), Gaps = 1/71 (1%) Query: 442 YRLEGWQGNPPPIYVGSSPTLKNYVRVVEVWWDEYKDYFYASR-PESQALPYGDISELKK 500 + E W G K + + + W++E D FY P++ + Y I Sbjct: 3 FPKEFWWGGATSGPQSEGRFAKQHRNLFDYWYEEEPDLFYDYVGPDTASDAYHQIESDLT 62 Query: 501 FREDHNCKSFK 511 S++ Sbjct: 63 LLASLGHNSYR 73 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.310 0.129 0.369 Lambda K H 0.267 0.0398 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 27,133,716 Number of Sequences: 36641 Number of extensions: 1156150 Number of successful extensions: 2834 Number of sequences better than 10.0: 44 Number of HSP's better than 10.0 without gapping: 24 Number of HSP's successfully gapped in prelim test: 49 Number of HSP's that attempted gapping in prelim test: 2657 Number of HSP's gapped (non-prelim): 117 length of query: 657 length of database: 10,336,785 effective HSP length: 103 effective length of query: 554 effective length of database: 6,562,762 effective search space: 3635770148 effective search space used: 3635770148 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 62 (28.5 bits)