BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q7XJJ7 (607 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 6DII-A nrPDB 1252 0.0 3AL0-A nrPDB 156 2e-38 3KFU-E nrPDB 154 1e-37 3H0L-A nrPDB 153 2e-37 4WJ3-A nrPDB 147 2e-35 6C6G-A nrPDB 137 1e-32 2DC0-A nrPDB 137 1e-32 2G5H-A nrPDB 132 3e-31 5H6S-A nrPDB 130 2e-30 3A1K-A nrPDB 112 5e-25 4YJI-A nrPDB 101 8e-22 4N0I-A nrPDB 92 5e-19 4GYR-A nrPDB 92 8e-19 3A2Q-A nrPDB 85 7e-17 1O9P-A nrPDB 64 2e-10 6MRG-A nrPDB 60 3e-09 3D8F-A nrPDB 34 0.19 4XFM-A nrPDB 30 3.6 2X0S-A nrPDB 28 9.0 4GIC-A nrPDB 28 9.5 >6DII-A nrPDB Length = 636 Score = 1252 bits (3239), Expect = 0.0, Method: Compositional matrix adjust. Identities = 607/607 (100%), Positives = 607/607 (100%) Query: 1 MGKYQVMKRASEVDLSTVKYKAETMKAPHLTGLSFKLFVNLLEAPLIGSLIVDYLKKDNG 60 MGKYQVMKRASEVDLSTVKYKAETMKAPHLTGLSFKLFVNLLEAPLIGSLIVDYLKKDNG Sbjct: 1 MGKYQVMKRASEVDLSTVKYKAETMKAPHLTGLSFKLFVNLLEAPLIGSLIVDYLKKDNG 60 Query: 61 MTKIFRNTVIPEEPMFRPEFPSQEPEHDVVIVGEDESPIDRLETALKCLPQYDPSRSLHA 120 MTKIFRNTVIPEEPMFRPEFPSQEPEHDVVIVGEDESPIDRLETALKCLPQYDPSRSLHA Sbjct: 61 MTKIFRNTVIPEEPMFRPEFPSQEPEHDVVIVGEDESPIDRLETALKCLPQYDPSRSLHA 120 Query: 121 DPVSSFRYWKIRDYAYAYRSKLTTPLQVAKRIISIIEEFGYDKPPTPFLIRFDANEVIKQ 180 DPVSSFRYWKIRDYAYAYRSKLTTPLQVAKRIISIIEEFGYDKPPTPFLIRFDANEVIKQ Sbjct: 121 DPVSSFRYWKIRDYAYAYRSKLTTPLQVAKRIISIIEEFGYDKPPTPFLIRFDANEVIKQ 180 Query: 181 AEASTRRFEQGNPISVLDGIFVTIKDDIDCLPHPTNGGTTWLHEDRSVEKDSAVVSKLRS 240 AEASTRRFEQGNPISVLDGIFVTIKDDIDCLPHPTNGGTTWLHEDRSVEKDSAVVSKLRS Sbjct: 181 AEASTRRFEQGNPISVLDGIFVTIKDDIDCLPHPTNGGTTWLHEDRSVEKDSAVVSKLRS 240 Query: 241 CGAILLGKANMHELGMGTTGNNSNYGTTRNPHDPKRYTGGSSSGSAAIVAAGLCSAALGT 300 CGAILLGKANMHELGMGTTGNNSNYGTTRNPHDPKRYTGGSSSGSAAIVAAGLCSAALGT Sbjct: 241 CGAILLGKANMHELGMGTTGNNSNYGTTRNPHDPKRYTGGSSSGSAAIVAAGLCSAALGT 300 Query: 301 DGGGSVRIPSALCGITGLKTTYGRTDMTGSLCEGGTVEIIGPLASSLEDAFLVYAAILGS 360 DGGGSVRIPSALCGITGLKTTYGRTDMTGSLCEGGTVEIIGPLASSLEDAFLVYAAILGS Sbjct: 301 DGGGSVRIPSALCGITGLKTTYGRTDMTGSLCEGGTVEIIGPLASSLEDAFLVYAAILGS 360 Query: 361 SSADRYNLKPSPPCFPKLLSHNGSNAIGSLRLGKYTKWFNDVSSSDISDKCEDILKLLSN 420 SSADRYNLKPSPPCFPKLLSHNGSNAIGSLRLGKYTKWFNDVSSSDISDKCEDILKLLSN Sbjct: 361 SSADRYNLKPSPPCFPKLLSHNGSNAIGSLRLGKYTKWFNDVSSSDISDKCEDILKLLSN 420 Query: 421 NHGCKVVEIVVPELEEMRAAHVISIGSPTLSSLTPYCEAGKNSKLSYDTRTSFAIFRSFS 480 NHGCKVVEIVVPELEEMRAAHVISIGSPTLSSLTPYCEAGKNSKLSYDTRTSFAIFRSFS Sbjct: 421 NHGCKVVEIVVPELEEMRAAHVISIGSPTLSSLTPYCEAGKNSKLSYDTRTSFAIFRSFS 480 Query: 481 ASDYIAAQCLRRRLMEYHLNIFKDVDVIVTPTTGMTAPVIPPDALKNGETNIQVTTDLMR 540 ASDYIAAQCLRRRLMEYHLNIFKDVDVIVTPTTGMTAPVIPPDALKNGETNIQVTTDLMR Sbjct: 481 ASDYIAAQCLRRRLMEYHLNIFKDVDVIVTPTTGMTAPVIPPDALKNGETNIQVTTDLMR 540 Query: 541 FVLAANLLGFPAISVPVGYDKEGLPIGLQIMGRPWAEATVLGLAAAVEELAPVTKKPAIF 600 FVLAANLLGFPAISVPVGYDKEGLPIGLQIMGRPWAEATVLGLAAAVEELAPVTKKPAIF Sbjct: 541 FVLAANLLGFPAISVPVGYDKEGLPIGLQIMGRPWAEATVLGLAAAVEELAPVTKKPAIF 600 Query: 601 YDILNTN 607 YDILNTN Sbjct: 601 YDILNTN 607 >3AL0-A nrPDB Length = 475 Score = 156 bits (395), Expect = 2e-38, Method: Compositional matrix adjust. Identities = 128/417 (30%), Positives = 205/417 (49%), Gaps = 38/417 (9%) Query: 199 GIFVTIKDDIDCLPHPTNGGTTWLHEDRSVEKDSAVVSKLRSCGAILLGKANMHELGMGT 258 GI V IKD+I L T + L SV D+ VV K++ G +++GKAN+ E MG+ Sbjct: 60 GIPVAIKDNILTLGMRTTCASRILENYESV-FDATVVKKMKEAGFVVVGKANLDEFAMGS 118 Query: 259 TGNNSNYGTTRNPHDPKRYTGGSSSGSAAIVAAGLCSAALGTDGGGSVRIPSALCGITGL 318 + S + TRNP D +R GGSS GSAA V+AG+ AALG+D GGSVR P++LCG+ G Sbjct: 119 STERSAFFPTRNPWDLERVPGGSSGGSAAAVSAGMVVAALGSDTGGSVRQPASLCGVVGY 178 Query: 319 KTTYGRTDMTGSLCEGGTVEIIGPLASSLEDAFLVYAAILGSSSADRYNLKPSPPCFPKL 378 K TYG G + +++ IGP+ ++ DA ++ I G D + ++ Sbjct: 179 KPTYGLVSRYGLVAFASSLDQIGPITKTVRDAAILMEIISGRDENDATTVNRKVDFLSEI 238 Query: 379 LSHNGSNAIGSLRLGKYTKWFNDVSSSDISDKCEDILKLLSNNHGCKVVEIVVPELEEMR 438 + ++ + + +S++ E+ LKLL G KV + +P ++ Sbjct: 239 -----EEGVSGMKFAVPEEIYEHDIEEGVSERFEEALKLL-ERLGAKVERVKIPHIKYSV 292 Query: 439 AAHVISIGSPTLSSLTPY---------CEAG--------KNSKLSYDTRT-----SFAIF 476 A + + + S+L + E G +N + R +F + Sbjct: 293 ATYYVIAPAEASSNLARFDGVKYGLRIKEKGLREMYMKTRNVGFGEEVRRRIMIGTFTLS 352 Query: 477 RSFSASDYIAAQCLRRRLMEYHLNIFKDVDVIVTPTTGMTAPVIPPDALKNGETNIQVTT 536 ++ + + A +RR++ + + D I+TPT+ P A K GE +T Sbjct: 353 AAYYEAYFNKAMKVRRKISDELNEVLSQYDAILTPTS-------PVTAFKIGEIKDPLTY 405 Query: 537 DLMR-FVLAANLLGFPAISVPVGYDKEGLPIGLQIMGRPWAEATVLGLAAAVEELAP 592 LM F + ANL G PAISVP G+ LP+G+Q++GR +A+ V +A A+E+ +P Sbjct: 406 YLMDIFTIPANLAGLPAISVPFGFSN-NLPVGVQVIGRRFADGKVFRIARAIEKNSP 461 >3KFU-E nrPDB Length = 471 Score = 154 bits (388), Expect = 1e-37, Method: Compositional matrix adjust. Identities = 154/470 (32%), Positives = 235/470 (50%), Gaps = 51/470 (10%) Query: 143 TTPLQVAKRIISIIEEFGYDKPPTPFLIRFDANE-VIKQAEASTRRFEQGNPISVLDGIF 201 +PL+VA+ + ++E D FL NE ++++AEA + G P++ G+ Sbjct: 15 VSPLEVAQAYLKRVQEL--DPGLGAFL---SLNERLLEEAEA----VDPGLPLA---GLV 62 Query: 202 VTIKDDIDCLPHPTNGGTTWLHEDRSVEKDSAVVSKLRSCGAILLGKANMHELGMGTTGN 261 V +KD+I T G+ L E+ ++ V++L++ GA++LGK N+ E GMG++ Sbjct: 63 VAVKDNIATRGLRTTAGSRLL-ENFVPPYEATAVARLKALGALVLGKTNLDEFGMGSSTE 121 Query: 262 NSNYGTTRNPHDPKRYTGGSSSGSAAIVAAGLCSAALGTDGGGSVRIPSALCGITGLKTT 321 +S + T+NP DP R GGSS GSAA +AA L ALG+D GGSVR P+A CG+ GLK T Sbjct: 122 HSAFFPTKNPFDPDRVPGGSSGGSAAALAADLAPLALGSDTGGSVRQPAAFCGVYGLKPT 181 Query: 322 YGRTDMTGSLCEGGTVEIIGPLASSLEDAFLVYAAILGSSSADRYNLKPSPPCFPKLLSH 381 YGR G + +++ IGP+A S+ D L+ A G D +L PP F + L Sbjct: 182 YGRVSRFGLIAYASSLDQIGPMARSVRDLALLMDAAAGPDPLDATSLD-LPPRFQEAL-- 238 Query: 382 NGSNAIGSLRLGKYTKWFNDVSSSDISDKCEDILKLLSNNHGCKVVEIVVPELEEMRAAH 441 + LRLG + +S + E+ LK+ G V E+ P L + AA+ Sbjct: 239 --EGPLPPLRLGVVREALAG-NSPGVERALEEALKVF-RELGLSVREVSWPSLPQALAAY 294 Query: 442 VISIGSPTLSSLTPY-------CEAGKNSK-LSYDTRT-------------SFAIFRSFS 480 I + S+L Y AG+ + + TR +F + + Sbjct: 295 YILAPAEASSNLARYDGTLYGRRAAGEEVEGMMEATRALFGLEVKRRVLVGTFVLSSGYY 354 Query: 481 ASDYIAAQCLRRRLMEYHLNIFKDVDVIVTPTTGMTAPVIPPDALKNGETNIQVTTDLMR 540 + Y AQ RRRL +F++VD+++ PTT P P A ++ + DL Sbjct: 355 EAYYGRAQAFRRRLKAEAQALFREVDLLLLPTT--PHPAFPFGARRDPLAMYR--EDL-- 408 Query: 541 FVLAANLLGFPAISVPVGYDKEGLPIGLQIMGRPWAE-ATVLGLAAAVEE 589 + + ANL G PA+S P G++ LP+GLQ++ PW E +L A A EE Sbjct: 409 YTVGANLTGLPALSFPAGFEGH-LPVGLQLLA-PWGEDERLLRAALAFEE 456 >3H0L-A nrPDB Length = 478 Score = 153 bits (387), Expect = 2e-37, Method: Compositional matrix adjust. Identities = 126/417 (30%), Positives = 205/417 (49%), Gaps = 37/417 (8%) Query: 197 LDGIFVTIKDDIDCLPHPTNGGTTWLHEDRSVEKDSAVVSKLRSCGAILLGKANMHELGM 256 L GI + +KD+I T + L E+ D+ V+ +L+ GA+++GK N+ E M Sbjct: 64 LFGIPIAVKDNILVEGEKTTCASKIL-ENFVAPYDATVIERLKKAGALIVGKTNLDEFAM 122 Query: 257 GTTGNNSNYGTTRNPHDPKRYTGGSSSGSAAIVAAGLCSAALGTDGGGSVRIPSALCGIT 316 G++ S + T+NP D +R GGSS GSAA VA +LG+D GGS+R P++ CG+ Sbjct: 123 GSSTEYSAFFPTKNPWDLERVPGGSSGGSAASVAVLSAPVSLGSDTGGSIRQPASFCGVI 182 Query: 317 GLKTTYGRTDMTGSLCEGGTVEIIGPLASSLEDAFLVYAAILGSSSADRYNLKPSPPCFP 376 G+K TYGR G + +++ IG ED LV I G D + K P + Sbjct: 183 GIKPTYGRVSRYGLVAFASSLDQIGVFGRRTEDVALVLEVISGWDEKDSTSAKVPVPEW- 241 Query: 377 KLLSHNGSNAIGSLRLGKYTKWFNDVSSSDISDKCEDILKLLSNNHGCKVVEIVVPELEE 436 S + L++G ++F + + E+ +K L G ++ E+ +P ++ Sbjct: 242 ---SEEVKKEVKGLKIGLPKEFFEYELQPQVKEAFENFIKEL-EKEGFEIKEVSLPHVKY 297 Query: 437 MRAAHVISIGSPTLSSLTPY--CEAGKNSKLSYD-----TRT----------------SF 473 + I S S+L Y G +K D RT +F Sbjct: 298 SIPTYYIIAPSEASSNLARYDGVRYGYRAKEYKDIFEMYARTRDEGFGPEVKRRIMLGTF 357 Query: 474 AIFRSFSASDYIAAQCLRRRLMEYHLNIFKDVDVIVTPTTGMTAPVIPPDALKNGETNIQ 533 A+ + + Y+ AQ +RR + L F++VDVI +PTT P +P + E I+ Sbjct: 358 ALSAGYYDAYYLKAQKVRRLITNDFLKAFEEVDVIASPTT----PTLPFKFGERLENPIE 413 Query: 534 V-TTDLMRFVLAANLLGFPAISVPVGYDKEGLPIGLQIMGRPWAEATVLGLAAAVEE 589 + +D++ + ANL G PAIS+P+ + K+GLP+G Q++G+ W E T+L ++ E+ Sbjct: 414 MYLSDIL--TVPANLAGLPAISIPIAW-KDGLPVGGQLIGKHWDETTLLQISYLWEQ 467 >4WJ3-A nrPDB Length = 484 Score = 147 bits (370), Expect = 2e-35, Method: Compositional matrix adjust. Identities = 136/449 (30%), Positives = 219/449 (48%), Gaps = 41/449 (9%) Query: 178 IKQAEASTRRFEQGNPISVLDGIFVTIKDDIDCLPHPTNGGTTWLHEDRSVEKDSAVVSK 237 I QA+A+ R G ++L G + KD T+ G+ L S D+ VV K Sbjct: 51 IAQAKAADERRANGENGALL-GAPIAHKDLFCTQGVRTSCGSKMLDNFVS-PYDATVVEK 108 Query: 238 LRSCGAILLGKANMHELGMGTTGNNSNYGTTRNPHDPKRYTGGSSSGSAAIVAAGLCSAA 297 L + GA+ LGK NM E MG++ +S+YG +NP R GGSS GSAA VAA L AA Sbjct: 109 LTAAGAVTLGKLNMDEFAMGSSNQSSHYGAVKNPWSLDRVPGGSSGGSAAAVAARLLPAA 168 Query: 298 LGTDGGGSVRIPSALCGITGLKTTYGRTDMTGSLCEGGTVEIIGPLASSLEDAFLVYAAI 357 GTD GGS+R P+AL +TG+K TYGR G + +++ GPLA + ED L+ + Sbjct: 169 TGTDTGGSIRQPAALTNLTGIKPTYGRVSRWGMIAYASSLDQGGPLARTAEDCALMLGVM 228 Query: 358 LGSSSADRYNLKPSPPCFPKLLSHNGSNAIGSLRLGKYTKWFNDVSSSDISDKCEDILKL 417 G D +++ + L + LR+G ++F S I+D +++ Sbjct: 229 AGFDPKDSTSVEQPVDDYLAAL----QKPLSGLRIGLPREYFGAGLDSRIADAVLAVVEE 284 Query: 418 LSNNHGCKVVEIVVPELEEMRAAHVISIGSPTLSSLTPY--------CEAGKNSKLSYDT 469 L G V +I +P ++ A+ + + S+L+ + C+A +N + Y Sbjct: 285 L-KTLGATVKDISLPNMQHAIPAYYVIAPAEASSNLSRFDGVRYGYRCDAPQNLEDLYKR 343 Query: 470 RT---------------SFAIFRSFSASDYIAAQCLRRRLMEYHLNIFKDVDVIVTPTTG 514 ++A+ + + Y+ AQ +RR + ++ F +VDVI+ PTT Sbjct: 344 SRAEGFGSEVKNRIMVGTYALSAGYYDAYYLQAQKIRRLIKNDFVSAFAEVDVILGPTT- 402 Query: 515 MTAPVIPPDALKNGETNIQVTTDLMR--FVLAANLLGFPAISVPVGYDKEGLPIGLQIMG 572 P A K GE N + + + + ANL G P +S+P G+ +GLP+G+Q++ Sbjct: 403 ------PNPAWKIGEKNDDPVSQYLEDIYTITANLAGLPGLSMPAGF-VDGLPVGVQLLA 455 Query: 573 RPWAEATVLGLAAAVEELAPV-TKKPAIF 600 + E +L +A ++++ T+ PA F Sbjct: 456 PYFQEGRLLNVAHQYQQVSDWHTRTPAGF 484 >6C6G-A nrPDB Length = 457 Score = 137 bits (346), Expect = 1e-32, Method: Compositional matrix adjust. Identities = 119/413 (28%), Positives = 193/413 (46%), Gaps = 31/413 (7%) Query: 180 QAEASTRRFEQGNPISVLDGIFVTIKDDIDCLPHPTNGGTTWLHEDRSVEKDSAVVSKLR 239 +A+A R +G + L G+ +K+ D T G+ D+ +V +L+ Sbjct: 49 EADAIDVRRARGEVLPPLAGLPYAVKNLFDIEGVTTLAGSKINRTLPPARADAVLVQRLK 108 Query: 240 SCGAILLGKANMHELGMGTTGNNSNYGTTRNPHDPKRYTGGSSSGSAAIVAAGLCSAALG 299 + GA+LLG NM E G T N++YG TRNPHD R GGSS GS A +AAG +LG Sbjct: 109 AAGAVLLGGLNMDEFAYGFTTENTHYGPTRNPHDTGRIAGGSSGGSGAAIAAGQVPLSLG 168 Query: 300 TDGGGSVRIPSALCGITGLKTTYGRTDMTGSLCEGGTVEIIGPLASSLEDAFLVYAAILG 359 +D GS+R+P++LCG+ GLK T+GR G+ +++ +GPLA S+E L Y A+ G Sbjct: 169 SDTNGSIRVPASLCGVWGLKPTFGRLSRRGTYPFVHSIDHLGPLADSVEGLALAYDAMQG 228 Query: 360 SSSAD----RYNLKPSPPCFPKLLSHNGSNAIGSLRLGKYTKWFNDVSSSDISDKCEDIL 415 D ++PS P S I LR+G WF D + + Sbjct: 229 PDPLDPGCSASRIQPSVPVL--------SQGIAGLRIGVLGGWFRDNAGPAARAAVDVAA 280 Query: 416 KLLSNNHGCKVVEIVV-PELEEMRAAHVISIGSPTLSSLTPYCEAGKNSKLSYDTRTSFA 474 L + E+V+ P+ E RAA + +++ C + ++ + Sbjct: 281 LTLGAS------EVVMWPDAEIGRAAAFV------ITASEGGCLHLDDLRIRPQDFEPLS 328 Query: 475 IFRSFSA-----SDYIAAQCLRRRLMEYHLNIFKDVDVIVTPTTGMTAPVIPPDALKNGE 529 + R S + Y+ AQ RR + +F+D D+++ P T ++AP I + ++ Sbjct: 329 VDRFISGVLQPVAWYLRAQRFRRVYRDKVNALFRDWDILIAPATPISAPAIGTEWIEVNG 388 Query: 530 TNIQVTTDLMRFVLAANLLGFPAISVPVG-YDKEGLPIGLQIMGRPWAEATVL 581 T + + G P ++ P + +G+PIG+Q++ PW E+ L Sbjct: 389 TRHPCRPAMGLLTQPVSFAGCPVVAAPTWPGENDGMPIGVQLIAAPWNESLCL 441 >2DC0-A nrPDB Length = 434 Score = 137 bits (345), Expect = 1e-32, Method: Compositional matrix adjust. Identities = 123/451 (27%), Positives = 193/451 (42%), Gaps = 40/451 (8%) Query: 143 TTPLQVAKRIISIIEEFGYDKPPTPFLIRFDANEVIKQAEASTRRFEQGNPISVLDGIFV 202 TTPL + + + + F D+ +L D K+A A T +G L G+ + Sbjct: 15 TTPLALLEEALERAKAF-QDRNALAYL---DEEAARKEALALTEELRRGQVRGPLHGLPL 70 Query: 203 TIKDDIDCLPHPTNGGTTWLHEDRSVEKDSAVVSKLRSCGAILLGKANMHELGMGTTGNN 262 T+KD PT GT + +++ V +LR GA+L K NMHE+ +G TG N Sbjct: 71 TVKDLFPVKGMPTRAGTK--APLPPLPEEARAVRRLREAGALLFAKTNMHEIALGITGEN 128 Query: 263 SNYGTTRNPHDPKRYTGGSSSGSAAIVAAGLCSAALGTDGGGSVRIPSALCGITGLKTTY 322 G RN DP R GGSS GSA VA G+ A+LGTD GGS+RIP+ G+ G K +Y Sbjct: 129 PWTGPVRNAVDPSRQAGGSSGGSAVAVALGIGLASLGTDTGGSIRIPAGFNGVVGFKPSY 188 Query: 323 GRTDMTGSLCEGGTVEIIGPLASSLEDAFLVYAAILGSSSADRYNLKPSPPCFPKLLSHN 382 GR + G+L + + GPL S+ DA + IL S ++ P F L Sbjct: 189 GRVSLEGALPLSRSTDHAGPLTRSVRDAHFL-TEILAGESIPLEGVQN--PVFGVPLDFL 245 Query: 383 GSNAIGSLRLGKYTKWFNDVSS-----SDISDKCEDILKLLSNNHGCKVVEIVVPELEEM 437 +G +T+ D+ + ++S E + ++ + L Sbjct: 246 -EGRLGVEVRKAFTRLLEDLPALRAEVREVSLPLEGVYEVYTR-------------LVRY 291 Query: 438 RAAHVISIGSPTLSSLTPYCEAGKNSKLSYDTRTSFAIFRSFSASDYIAAQCLRRRLMEY 497 AA + +L + E S R + + + DY A R L Sbjct: 292 EAARIHE------KALKEHPEG-----FSPQVREALLAGLALTEKDYRDAVAEREALRLE 340 Query: 498 HLNIFKDVDVIVTPTTGMTAPVIPPDALKNGETNIQVTTDLMRFVLAANLLGFPAISVPV 557 + + VD ++ P + AP + + ++ + L +LLG P +++P Sbjct: 341 LVKALRGVDALLLPVQPLPAPPLGTEEVELESGRKGHREAFITLTLPFSLLGVPTLALPF 400 Query: 558 GYDKEGLPIGLQIMGRPWAEATVLGLAAAVE 588 EG+P+GLQ++G + VL L +E Sbjct: 401 A-KVEGMPVGLQVVGAYGEDGKVLALGGWLE 430 >2G5H-A nrPDB Length = 485 Score = 132 bits (333), Expect = 3e-31, Method: Compositional matrix adjust. Identities = 139/489 (28%), Positives = 214/489 (43%), Gaps = 42/489 (8%) Query: 125 SFRYWKIRDYAYAYRSKLTTPLQVAKRIISIIEEFGYDKPPTPFLIRFDANEVIKQAEAS 184 S RY + + + K P V K I IEE P + D IK+A+ Sbjct: 2 SIRYESVENLLTLIKDKKIKPSDVVKDIYDAIEE---TDPTIKSFLALDKENAIKKAQEL 58 Query: 185 TRRFEQGNPISVLDGIFVTIKDDIDCLPHPTNGGTTWLHEDRSVEKDSAVVSKLRSCGAI 244 + L GI + IKD+I T + L + +S V+ KL A+ Sbjct: 59 DELQAKDQMDGKLFGIPMGIKDNIITNGLETTCASKMLEGFVPI-YESTVMEKLHKENAV 117 Query: 245 LLGKANMHELGMGTTGNNSNYGTTRNPHDPKRYTGGSSSGSAAIVAAGLCSAALGTDGGG 304 L+GK NM E MG + S + T NP D K GGSS GSAA VAAGL +LG+D GG Sbjct: 118 LIGKLNMDEFAMGGSTETSYFKKTVNPFDHKAVPGGSSGGSAAAVAAGLVPLSLGSDTGG 177 Query: 305 SVRIPSALCGITGLKTTYGRTDMTGSLCEGGTVEIIGPLASSLEDAFLVYAAILGSSSAD 364 S+R P+A CG+ G+K TYGR G + +++ IGPL +++D +V AI G+ D Sbjct: 178 SIRQPAAYCGVVGMKPTYGRVSRFGLVAFASSLDQIGPLTRNVKDNAIVLEAISGADVND 237 Query: 365 RYNLKPSPPCFPKLLSHNGSNAIGSLRLGKYTKWFNDVSSSDISDKCEDILKLLSNNHGC 424 S P + I L++ ++ + + D+ + ++ ++ L + G Sbjct: 238 ----STSAPVDDVDFTSEIGKDIKGLKVALPKEYLGEGVADDVKEAVQNAVETL-KSLGA 292 Query: 425 KVVEIVVPELEEMRAAHVISIGSPTLSSLTPY--CEAGKNSKLSYDTRT----------- 471 V E+ +P + ++ + S S+L+ + G +SK ++ Sbjct: 293 VVEEVSLPNTKFGIPSYYVIASSEASSNLSRFDGIRYGYHSKEAHSLEELYKMSRSEGFG 352 Query: 472 ----------SFAIFRSFSASDYIAAQCLRRRLMEYHLNIFKDVDVIVTPTTGMTAPVIP 521 +FA+ + + Y +Q +R + +F++ DV+V PT P Sbjct: 353 KEVKRRIFLGTFALSSGYYDAYYKKSQKVRTLIKNDFDKVFENYDVVVGPTA-------P 405 Query: 522 PDALKNGETNIQVTTDLMRFVLA--ANLLGFPAISVPVGYDKEGLPIGLQIMGRPWAEAT 579 A GE T +L NL G P ISVP G G PIGLQ +G+P+ E T Sbjct: 406 TTAFNLGEEIDDPLTMYANDLLTTPVNLAGLPGISVPCG-QSNGRPIGLQFIGKPFDEKT 464 Query: 580 VLGLAAAVE 588 + +A E Sbjct: 465 LYRVAYQYE 473 >5H6S-A nrPDB Length = 481 Score = 130 bits (327), Expect = 2e-30, Method: Compositional matrix adjust. Identities = 130/465 (27%), Positives = 207/465 (44%), Gaps = 42/465 (9%) Query: 147 QVAKRIISIIEEFGYDKPPTPFLIRFDANEVIKQAEASTRRFEQ--GNPISVLDGIFVTI 204 +V + I+EF T + A++V+++A A+ R F G P LDG+ ++I Sbjct: 47 EVVHEHLDRIDEF---NALTNSFVELRADQVLEEARAADREFGSTLGGP---LDGVPLSI 100 Query: 205 KDDIDCLP-HPTNGGTTWLHEDRSVEKDSAVVSKLRSCGAILLGKANMHELGMGTTGNNS 263 KD H T+G ++ D +D ++LR+ G ++LG A + +L + + Sbjct: 101 KDSYSVAGLHRTDG--LPVNADVLDAQDDVATARLRAAGGLVLGHAGIPDLCIRWNSVSG 158 Query: 264 NYGTTRNPHDPKRYTGGSSSGSAAIVAAGLCSAALGTDGGGSVRIPSALCGITGLKTTYG 323 YG RNP D R GGSS G AA VAAG + LG D GGS+R+P++ CG+ G +T G Sbjct: 159 LYGAVRNPRDLSRTAGGSSGGDAANVAAGFATIGLGGDLGGSIRVPASWCGVYGFRTGPG 218 Query: 324 R---TDMTGSLCEGGTVEI---IGPLASSLEDAFLVYAAILGSSSADRYNLKPSPPCFPK 377 R + G +E+ IGP+A S++D L + + G DR + SP + Sbjct: 219 RIPDVNPNGGRSRNVVMELMAQIGPIARSIDDIELAFRIMTG---VDRRDTMSSPLGLIE 275 Query: 378 LLSHNGSNAIGSLRLGKYTKWFNDVSSSDISDKCEDILKLLSNNHGCKVVEIVVPELEEM 437 I + R+ V S + ++ + +++L G V E V+P+L Sbjct: 276 --------PIEAPRVAVLRHETGAVLDSSVEEQLDATIEML-RAEGYVVEENVLPDLHRA 326 Query: 438 RAAHVISIGSPTLSSLTP-YCEAGKNSKLSYDTRTSFAIFRSFSASDYIAAQCLRRRLME 496 +G+ + + P E S+ + A Y+ A R + Sbjct: 327 PEVWAEIVGTELIHRVLPEVAELVIASERMHIVDMFGAYELGADVGAYLTALEERSSIQM 386 Query: 497 YHLNIFKDVDVIVTPTTGMTAPVIPPDALKNGETNIQVTTDLMRFVLAANLLGFPAISVP 556 + + +I+ P GM AP + D E +I + D MR V NLLG P+++ Sbjct: 387 TVAALMERYQLILAPVAGMPAPPLDFDDHIGREASIAL-FDQMRCVPWVNLLGLPSLA-- 443 Query: 557 VGYDKEGLPIGLQIMGRPWAEATVLGLAAAVEELAPVTK--KPAI 599 LP G+Q++GR E T+L A E AP + PAI Sbjct: 444 -------LPNGIQLVGRKHDELTILAAGRAYERRAPRVEIATPAI 481 >3A1K-A nrPDB Length = 521 Score = 112 bits (279), Expect = 5e-25, Method: Compositional matrix adjust. Identities = 128/439 (29%), Positives = 194/439 (44%), Gaps = 53/439 (12%) Query: 196 VLDGIFVTIKDDIDCLPHPTNGGTTWLHEDRSVE-----KDSAVVSKLRSCGAILLGKAN 250 VL G V IKD++ T G ++ R+VE +D+ VV++L + GA + GKA Sbjct: 87 VLTGRRVAIKDNV------TVAGVPMMNGSRTVEGFTPSRDATVVTRLLAAGATVAGKAV 140 Query: 251 MHELGMGTTGNNSNYGTTRNPHDPKRYTGGSSSGSAAIVAAGLCSAALGTDGGGSVRIPS 310 +L + G RNP D +R GGSS GSAA+VA G A+G D GGS+RIP+ Sbjct: 141 CEDLCFSGSSFTPASGPVRNPWDRQREAGGSSGGSAALVANGDVDFAIGGDQGGSIRIPA 200 Query: 311 ALCGITGLKTTYGRTDMTGSLCEGGTVEIIGPLASSLEDAFLVYAAILGSSSADRYNLKP 370 A CG+ G K T+G TG+ T++ +GP+ ++ DA L+ + I G D Sbjct: 201 AFCGVVGHKPTFGLVPYTGAFPIERTIDHLGPITRTVHDAALMLSVIAGRDGNDPRQADS 260 Query: 371 SPPCFPKLLSHNGSNAIGSLRLGKYTKWF-NDVSSSDISDKCEDILKLLSNNHGCKVVEI 429 LS S+ G LR+G + F + VS ++ D L+ GC V E+ Sbjct: 261 VEAG--DYLSTLDSDVDG-LRIGIVREGFGHAVSQPEVDDAVRAAAHSLTEI-GCTVEEV 316 Query: 430 VVPELEEMRAAHVISI-----GSPTLSSLTPYCEAGKNSKLSYDTR--TSFAIFR----- 477 +P + A H+ ++ G+ + Y G N++ YD FA R Sbjct: 317 NIP--WHLHAFHIWNVIATDGGAYQMLDGNGY---GMNAEGLYDPELMAHFASRRIQHAD 371 Query: 478 ------------------SFSASDYIAAQCLRRRLMEYHLNIFKDVDVIVTPTTGMTAPV 519 + + Y A+ L + + DV+V PT A Sbjct: 372 ALSETVKLVALTGHHGITTLGGASYGKARNLVPLARAAYDTALRQFDVLVMPTLPYVASE 431 Query: 520 IPPDALKNGETNIQVTTDLMRFVLAANLLGFPAISVPVGYDKEGLPIGLQIMGRPWAEAT 579 +P + T I ++ ++ G P++SVP G GLP+G+ I GR + +AT Sbjct: 432 LPAKDVDRA-TFITKALGMIANTAPFDVTGHPSLSVPAGL-VNGLPVGMMITGRHFDDAT 489 Query: 580 VLGLAAAVEELAPVTKKPA 598 VL + A E+L PA Sbjct: 490 VLRVGRAFEKLRGAFPTPA 508 >4YJI-A nrPDB Length = 495 Score = 101 bits (252), Expect = 8e-22, Method: Compositional matrix adjust. Identities = 128/483 (26%), Positives = 209/483 (43%), Gaps = 32/483 (6%) Query: 139 RSKLTTPLQVAKRIISIIEEFGYDKPPTPFLIRFDA-NEVIKQAEASTRRFEQGNPISVL 197 +SK +P +V + I +IE+ + P + + A +E ++A A RR QG P+ +L Sbjct: 21 KSKQISPREVVESTIDLIEQ----RDPGLNAVVYKAYDEAREKAAALERRIMQGEPVGML 76 Query: 198 DGIFVTIKDDIDCLPH--PTNGGTTWLHEDRSVEKD-SAVVSKLRSCGAILLGKANMHEL 254 G+ +KD P T GG L + R S K+ ++LLG+ N Sbjct: 77 AGVPTLMKDLFAAKPGWPSTLGGIRALKDARGAAGVWSTYPLKMSGEDSLLLGQTNSPVY 136 Query: 255 GMGTTGNNSNYGTTRNPHDPKRYTGGSSSGSAAIVAAGLCSAALGTDGGGSVRIPSALCG 314 G T +N+ +G TRNP + GGSS G+AA+VA G+ A GTDGGG++RIP+A Sbjct: 137 GFRGTTDNTFFGPTRNPFNLDFNAGGSSGGAAALVADGIVPVAGGTDGGGAIRIPAAWTN 196 Query: 315 ITGLKTTYGRTDMTG--SLCEGGTVEIIGPLASSLEDAFLVYAAILGSSSADRYNLKPSP 372 G + + GR + G GP+ ++ DA L + G D +L+ Sbjct: 197 TYGFQPSIGRVPFKSRPNAFHPGPYLYEGPITRTVRDAALAMNVLHGFDRRDPASLRVKL 256 Query: 373 PCFPKLLSHNGSNAIG-SLRLGKYTKWFNDVSSSDISDKCEDILKLLSNNHGCKVVEIVV 431 L IG +L G + D+ K + L + + V++ + Sbjct: 257 DFTSALAQGVRGKKIGLTLNYGVFPV---QQEIQDLIGKAARVFTELGAH--VEFVDLGI 311 Query: 432 P-ELEEMRAAHVISIGSPTLSSLTPYCEAGKNSKLSYDTRTSFAIFRSFSASDYI----- 485 P ++M A I PT++S+ + G + + A+ + A I Sbjct: 312 PYSQKQMSDAWCRMIAIPTVASMQALRKEGIDLYGEHRADIPDALMKWIDAVADISVQQI 371 Query: 486 -AAQCLRRRLMEYHLNIFKDVDVIVTPTTGMTAPVIPPDALKNGETNI--QVTTDLMRFV 542 A Q LR + + +F D+++ PT D G + I + L+ + Sbjct: 372 SADQLLRTTVFDCMNGVFDRFDLLLAPTLACMPVRNATDGCTEGPSQINGEEIDPLIGWC 431 Query: 543 LA--ANLLGFPAISVPVGYDKEGLPIGLQIMGRPWAEATVLGLAAAVEELAPVTKKPAIF 600 + N G P+ SVP G +GLP G+ I+G A+ V+ +AA E +P ++ + Sbjct: 432 MTYLTNFSGHPSASVPAGL-IDGLPAGMLIIGDRQADLDVIAASAAFERASPWSQ----Y 486 Query: 601 YDI 603 YDI Sbjct: 487 YDI 489 >4N0I-A nrPDB Length = 464 Score = 92.4 bits (228), Expect = 5e-19, Method: Compositional matrix adjust. Identities = 113/433 (26%), Positives = 196/433 (45%), Gaps = 55/433 (12%) Query: 197 LDGIFVTIKDDIDCLPHPTNGGTTWLHEDRSVEKDSAVVSKLRSCGAILLGKANMHELGM 256 L G +IKD+I PT + L +S D+ VV L+ G +LGK N+ E GM Sbjct: 44 LTGCVASIKDNIVTKDFPTTCASHILENFKS-PFDATVVKLLKQAGVHILGKTNLDEFGM 102 Query: 257 GTTGNNSNYGTTRNP---HDPKRYTGGSSSGSAAIVAAGLCSAALGTDGGGSVRIPSALC 313 G+ G +S G NP H+ K+ GGSSSG+AA VA L ALGTD GGSVR+P+ Sbjct: 103 GSGGVHSIRGPVINPLYPHEDKKIMGGSSSGAAASVACDLVDFALGTDTGGSVRLPACYG 162 Query: 314 GITGLKTTYGRTDMTGSLCEGGTVEIIGPLASSLEDAFLVYAAILGSSSADRYNLKPSPP 373 + G K +YGR G + +++ +G L+ + V+ + D+Y++K Sbjct: 163 SVLGFKPSYGRLSRFGVIAYSQSLDTVGILSKKINVLRKVFHTL------DKYDMKDPTS 216 Query: 374 CFPKL--LSHNGSNAIGSLRLGKYTKWFNDVSSSDISDKCEDILKLLSNNHGCKVVEIVV 431 +L L L++G ++ ++ +L+ L N G ++ + + Sbjct: 217 LSVELRELIEGNKKVRRPLKVGIVKEFSHESMPIGFHRLYLSLLEKLI-NLGLEIYPVSI 275 Query: 432 PELEEMRAAHVISIGSPTLSSLTPY--CEAG--------KNSKLSYDTRTSFA------- 474 P ++ + + S+L+ Y G K+ L TR+ F Sbjct: 276 PSVKNCLPIYYTLSPAEAASNLSRYDGIRYGYRDSELDIKDGILFAPTRSKFGTEVKNRI 335 Query: 475 IFRSFS------ASDYIAAQCLRRRLMEYHLNIFKDVDVIVTPT---TGMTAPVIP---- 521 I +++ +++I A+ LR L++ IF+ +V+ G+ ++P Sbjct: 336 ILGNYNLCSDAFKNNFIKAEKLRVNLIDEFDGIFRFPNVLTNSKGNPDGLDLLIVPTSSK 395 Query: 522 -PDALKNGETN------IQVTTDLMRFVLAANLLGFPAISVPVGYDKEGLPIGLQIMGRP 574 P ++++ E D+ F + +L G P++S+P+ KE PIGLQ++G+ Sbjct: 396 LPGSIRDFEEEEAKSPANSYINDV--FTVPMSLAGLPSLSMPL---KEKTPIGLQVVGQY 450 Query: 575 WAEATVLGLAAAV 587 ++TVL ++ Sbjct: 451 GDDSTVLDFVESI 463 >4GYR-A nrPDB Length = 621 Score = 91.7 bits (226), Expect = 8e-19, Method: Compositional matrix adjust. Identities = 111/402 (27%), Positives = 187/402 (46%), Gaps = 28/402 (6%) Query: 175 NEVIKQAEASTRRFEQGNPISVLDGIFVTIKDDIDCLPHPTNGGT-TWLHEDRSVEKDSA 233 EV+ +A A G P L G+ +KD+ID P + + +E ++D+ Sbjct: 76 EEVLAEARALDASPATGKP---LYGVPFAVKDNIDVAGLPCSAACPAFTYEP---DRDAT 129 Query: 234 VVSKLRSCGAILLGKANMHELGMGTTGNNSNYGTTRNPHDPKRYTGGSSSGSAAIVAAGL 293 VV++LR+ GAI+LGK N+ + G G S +G R D +GGSSSGSA VAAGL Sbjct: 130 VVARLRAAGAIVLGKTNLDQFATGLVGTRSPFGAPRCVFDQDYISGGSSSGSAVAVAAGL 189 Query: 294 CSAALGTDGGGSVRIPSALCGITGLKTTYGRTDMTGSLCEGGTVEIIGPLASSLEDAFLV 353 + +LGTD GS R+P+A + G+K T G +G + +++ + A+S+ + L+ Sbjct: 190 VAFSLGTDTAGSGRVPAAFNNLVGVKPTKGLLSTSGVVPACRSLDCVTVFAASVAEGTLI 249 Query: 354 YAAILGSSSADRYNLKPSPPCFPKLLSHNGSNAIGSLRLGKYTKWFNDVSSSDISDKCED 413 G +AD Y S P + L H G +G R + + N ++ ++ Sbjct: 250 RRIAEGYDAADPY----SRPSQKRRLPHVGLR-VGVPRQDQREFYGNTAYAALYQRALDE 304 Query: 414 ILKLLSNNHGCKVVEIVVPELEEMRAAHVISIGSPTLSS-LTPYCEAGKNSKLSYD--TR 470 ++ L ++VEI + R A + G P ++ L + + S+D R Sbjct: 305 MISL-----DAELVEI---DFAPFRDAAKLLYGGPWVAERLEAVGDHLSRAPDSFDPVVR 356 Query: 471 TSFAIFRSFSASDYIAAQCLRRRLMEYHLNIFKDVDVIVTPTTGMTAPVIPPDALKNGET 530 + ++ SA D Q L + + +D+++ P TAP I + Sbjct: 357 SIVETAKTLSAVDAFRGQYELAALTQQANAQWARMDILLLP----TAPTIHKVEAVMADP 412 Query: 531 NIQVTTDLMRFVLAANLLGFPAISVPVGYDKEGLPIGLQIMG 572 +++ + L + NLL AI+VP G+ + GLP G+ ++G Sbjct: 413 -VRLNSQLGHYTNFVNLLDCAAIAVPAGFIETGLPFGVTLVG 453 >3A2Q-A nrPDB Length = 493 Score = 85.1 bits (209), Expect = 7e-17, Method: Compositional matrix adjust. Identities = 110/396 (27%), Positives = 169/396 (42%), Gaps = 33/396 (8%) Query: 229 EKDSAVVSKLRSCGAILLGKANMHELGMGTTGNNSNYGTTRNPHDPKRYTGGSSSGSAAI 288 + D+ V ++R+ G +LLGK N E+G T +G TRNP + R GGSS GS A Sbjct: 98 DHDAYFVQRMRAAGFVLLGKTNTPEMGNQVTTEPEAWGATRNPWNLGRSVGGSSGGSGAA 157 Query: 289 VAAGLCSAALGTDGGGSVRIPSALCGITGLKTTYGRTD----MTGSLCEGGTVEIIGPLA 344 VAA L A G D G+VRIP+++CG+ GLK T GR +T S G G A Sbjct: 158 VAAALSPVAHGNDAAGAVRIPASVCGVVGLKPTRGRISPGPLVTDSDNVAGAAH-EGLFA 216 Query: 345 SSLEDAFLVYAAILGSSSADRYNLKPSPPCFPKLLSHNGSNAIGSLRLGKYTKWFNDVSS 404 S+ D + + G D + + + + +S N GSLR+G T N V Sbjct: 217 RSVRDIAALLDVVSGHRPGDTFCAPTASRPYAQGISENP----GSLRVGVLTH--NPVGD 270 Query: 405 SDISDKCEDILKLLSNNHGCKVVEIVVPELEEMRAAHVISIGSPTLSSLTPYCEAGKNSK 464 + +C + + ++ E + + S T+ + E +N + Sbjct: 271 FALDPECAAAARGAAAALAALGHDVNDAYPEALGDRSFLKDYS-TICDVAIAREIERNGE 329 Query: 465 L-------------SYDT--RTSFAIFRSFSAS----DYIAAQCLRRRLMEYHLNIFKDV 505 L S++ R R+F+A Y A + R + L I V Sbjct: 330 LIGRPLTEDDVEWTSWEMVKRADQVTGRAFAACVDELRYYAGKVERWWEAGWDLLILPTV 389 Query: 506 DVIVTPTTGMTAPVIPPDALKNGETNIQVTTDLMRFVLAANLLGFPAISVPVGYDKEGLP 565 TP G D I + ++ F + N+ G PAIS+P+G +G+P Sbjct: 390 -TRQTPEIGELMLAKGTDLEGRQSAFISGSLQMLAFTVPFNVSGQPAISLPIGMSSDGMP 448 Query: 566 IGLQIMGRPWAEATVLGLAAAVEELAP-VTKKPAIF 600 IG+QI+ E +L +AA +E P V ++P + Sbjct: 449 IGVQIVAAYGREDLLLQVAAQLEGALPWVARRPQLL 484 >1O9P-A nrPDB Length = 414 Score = 63.9 bits (154), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 104/395 (26%), Positives = 159/395 (40%), Gaps = 42/395 (10%) Query: 197 LDGIFVTIKDDIDCLPHPTNGGTTWLHEDRSVEKDSAVVSKLRSCGAILLGKANMHELGM 256 L GI V IKD ID PT G+ ++ D+ VV L+ GA ++GK Sbjct: 54 LRGIAVGIKDIIDTANMPTEMGSE-IYRGWQPRSDAPVVMMLKRAGATIIGKTTT----- 107 Query: 257 GTTGNNSNYGTTRNPHDPKRYTGGSSSGSAAIVAAGLCSAALGTDGGGSVRIPSALCGIT 316 T + + T NPH+ GG+SSGSAA V AG+ ALGT GGSV P+A CG Sbjct: 108 -TAFASRDPTATLNPHNTGHSPGGASSGSAAAVGAGMIPLALGTQTGGSVIRPAAYCGTA 166 Query: 317 GLKTTYGRTDMTGSLCEGGTVEIIGPLASSLEDAFLVYAAILGSSSADRYNLKPSPPCFP 376 +K ++ G C ++ +G + ED A+ G S +P Sbjct: 167 AIKPSFRMLPTVGVKCYSWALDTVGLFGARAEDLARGLLAMTGRSEFSGIVPAKAP---- 222 Query: 377 KLLSHNGSNAIGSLRLGKYTKWFNDVSSSDISDKCEDILKLLSNNHGCKVVEIVVPEL-- 434 R+G + F + +K + G V I +PE Sbjct: 223 --------------RIGVVRQEFAGAVEPAAEQGLQAAIK-AAERAGASVQAIDLPEAVH 267 Query: 435 EEMRAAHVISIGSPTLSSLTPYCEAGKNSKLSYDTRTSFAIFRSFSASDYIAAQCLRRRL 494 E R +I + + E + +++ R S + +Y A+ + RR Sbjct: 268 EAWRIHPIIQDFEAHRALAWEFSE--HHDEIAPMLRASLDATVGLTPKEYDEARRIGRRG 325 Query: 495 MEYHLNIFKDVDVIVTPTTGMTAPVIPPDALKNGETNIQVTTDLMRFVLAANLLGFPAIS 554 +F+ VDV++T + TAP +T R+ L+G P ++ Sbjct: 326 RRELGEVFEGVDVLLTYSAPGTAP-----------AKALASTGDPRYNRLWTLMGNPCVN 374 Query: 555 VPVGYDKEGLPIGLQIMGRPWAEATVLGLAAAVEE 589 VPV GLPIG+Q++ R +A L A +E+ Sbjct: 375 VPV-LKVGGLPIGVQVIARFGNDAHALATAWFLED 408 >6MRG-A nrPDB Length = 580 Score = 59.7 bits (143), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 54/157 (34%), Positives = 78/157 (49%), Gaps = 5/157 (3%) Query: 196 VLDGIFVTIKDDIDCLPHPTNGGTTWLHEDRSVEKDSAVVSKLRSCGAILLGKANMHELG 255 +L G+ V++K+ H + G + L+E E D VV L+ GA+ N+ + Sbjct: 134 LLYGVPVSLKECFSYKGHDSTLGLS-LNEGMPSESDCVVVQVLKLQGAVPFVHTNVPQSM 192 Query: 256 MGTTGNNSNYGTTRNPHDPKRYTGGSSSGSAAIVAAGLCSAALGTDGGGSVRIPSALCGI 315 +N +G T NP + GGSS G A++ +G LGTD GGS+R PSA CGI Sbjct: 193 FSYDCSNPLFGQTMNPWKSSKSPGGSSGGEGALIGSGGSPLGLGTDIGGSIRFPSAFCGI 252 Query: 316 TGLKTTYGRTDMTG-SLCEGGTVEI---IGPLASSLE 348 GLK T R +G C G + +GP+A +E Sbjct: 253 CGLKPTGNRLSKSGLKGCVYGQTAVQLSLGPMARDVE 289 Score = 32.3 bits (72), Expect = 0.57, Method: Compositional matrix adjust. Identities = 30/124 (24%), Positives = 45/124 (36%), Gaps = 39/124 (31%) Query: 504 DVDVIVTPTTGMTAPVIPPDALKNGETNIQVTTDLMRFVLAANLLGFPAISVPV------ 557 ++DV++TP G + P T + + + N L FPA VPV Sbjct: 467 NLDVLLTPMLGPALDLNTPGR----------ATGAVSYTMLYNCLDFPAGVVPVTTVTAE 516 Query: 558 ---------GY--------------DKEGLPIGLQIMGRPWAEATVLGLAAAVEELAPVT 594 GY + GLP+ +Q + PW E L VE+L Sbjct: 517 DDAQMELYKGYFGDIWDIILKKAMKNSVGLPVAVQCVALPWQEELCLRFMREVEQLMTPQ 576 Query: 595 KKPA 598 K+P+ Sbjct: 577 KQPS 580 >3D8F-A nrPDB Length = 148 Score = 33.9 bits (76), Expect = 0.19, Method: Compositional matrix adjust. Identities = 21/62 (33%), Positives = 29/62 (46%), Gaps = 7/62 (11%) Query: 93 GEDESPIDRLETALKCLPQYDPSRSLHADPVSSFRYWKI-------RDYAYAYRSKLTTP 145 GE + + +LE L + LHA P+ S R W + RD+AY R KLT Sbjct: 52 GEGKDLLLQLEDETLKLVEPQSQALLHAQPIISIRVWGVGRDSGRERDFAYVARDKLTQM 111 Query: 146 LQ 147 L+ Sbjct: 112 LK 113 >4XFM-A nrPDB Length = 464 Score = 29.6 bits (65), Expect = 3.6, Method: Compositional matrix adjust. Identities = 12/28 (42%), Positives = 19/28 (67%) Query: 399 FNDVSSSDISDKCEDILKLLSNNHGCKV 426 F+ SS+ ++ +CED LK L+N H C + Sbjct: 305 FSPDSSTVMASQCEDALKALTNGHHCII 332 >2X0S-A nrPDB Length = 913 Score = 28.5 bits (62), Expect = 9.0, Method: Compositional matrix adjust. Identities = 17/63 (26%), Positives = 32/63 (50%) Query: 386 AIGSLRLGKYTKWFNDVSSSDISDKCEDILKLLSNNHGCKVVEIVVPELEEMRAAHVISI 445 A+ ++ + TK+ D+++SD+ + C+ L+L GC + V +L A S Sbjct: 161 ALSRMKERRGTKFDTDLTASDLKELCDGYLELFELKTGCSFPQDPVMQLFAAIKAVFRSW 220 Query: 446 GSP 448 G+P Sbjct: 221 GNP 223 >4GIC-A nrPDB Length = 423 Score = 28.5 bits (62), Expect = 9.5, Method: Compositional matrix adjust. Identities = 17/50 (34%), Positives = 23/50 (46%), Gaps = 3/50 (6%) Query: 223 HEDRSVEKDSAVVSKLRSCGAILLGKANMHELGMGTTGNNS---NYGTTR 269 H + SVE +V +R+ GAI +G+ LG G N GT R Sbjct: 334 HLELSVESPEVLVESIRNAGAIFMGRYTAEALGDYCAGPNHVLPTSGTAR 383 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 6DII-A nrPDB 893 0.0 2G5H-A nrPDB 460 e-130 4WJ3-A nrPDB 439 e-123 3H0L-A nrPDB 429 e-120 3AL0-A nrPDB 397 e-111 4YJI-A nrPDB 396 e-110 6C6G-A nrPDB 387 e-108 5H6S-A nrPDB 387 e-108 3KFU-E nrPDB 379 e-105 2DC0-A nrPDB 373 e-103 3A1K-A nrPDB 343 1e-94 4N0I-A nrPDB 316 2e-86 4GYR-A nrPDB 311 6e-85 3A2Q-A nrPDB 310 8e-85 1O9P-A nrPDB 303 1e-82 6MRG-A nrPDB 178 4e-45 Sequences not found previously or not previously below threshold: 4DPQ-A nrPDB 34 0.14 6C44-A nrPDB 33 0.35 3TUU-A nrPDB 33 0.40 3JS4-A nrPDB 32 0.60 3D8F-A nrPDB 32 0.77 5Z0R-A nrPDB 32 0.78 5YGH-A nrPDB 32 0.92 3GOA-A nrPDB 32 0.97 5GMX-A nrPDB 31 1.2 2GAG-A nrPDB 31 1.2 2OWM-A nrPDB 31 1.7 4XWT-A nrPDB 30 2.7 2E5V-A nrPDB 30 2.8 5L9W-B nrPDB 30 3.0 5VKU-h nrPDB 30 3.6 4HJH-A nrPDB 29 4.3 1VRQ-A nrPDB 29 4.4 2FB9-A nrPDB 29 4.7 2IOU-G nrPDB 29 5.1 3TKT-A nrPDB 29 5.3 4WJI-A nrPDB 29 5.7 CONVERGED! >6DII-A nrPDB Length = 636 Score = 893 bits (2308), Expect = 0.0, Method: Composition-based stats. Identities = 607/607 (100%), Positives = 607/607 (100%) Query: 1 MGKYQVMKRASEVDLSTVKYKAETMKAPHLTGLSFKLFVNLLEAPLIGSLIVDYLKKDNG 60 MGKYQVMKRASEVDLSTVKYKAETMKAPHLTGLSFKLFVNLLEAPLIGSLIVDYLKKDNG Sbjct: 1 MGKYQVMKRASEVDLSTVKYKAETMKAPHLTGLSFKLFVNLLEAPLIGSLIVDYLKKDNG 60 Query: 61 MTKIFRNTVIPEEPMFRPEFPSQEPEHDVVIVGEDESPIDRLETALKCLPQYDPSRSLHA 120 MTKIFRNTVIPEEPMFRPEFPSQEPEHDVVIVGEDESPIDRLETALKCLPQYDPSRSLHA Sbjct: 61 MTKIFRNTVIPEEPMFRPEFPSQEPEHDVVIVGEDESPIDRLETALKCLPQYDPSRSLHA 120 Query: 121 DPVSSFRYWKIRDYAYAYRSKLTTPLQVAKRIISIIEEFGYDKPPTPFLIRFDANEVIKQ 180 DPVSSFRYWKIRDYAYAYRSKLTTPLQVAKRIISIIEEFGYDKPPTPFLIRFDANEVIKQ Sbjct: 121 DPVSSFRYWKIRDYAYAYRSKLTTPLQVAKRIISIIEEFGYDKPPTPFLIRFDANEVIKQ 180 Query: 181 AEASTRRFEQGNPISVLDGIFVTIKDDIDCLPHPTNGGTTWLHEDRSVEKDSAVVSKLRS 240 AEASTRRFEQGNPISVLDGIFVTIKDDIDCLPHPTNGGTTWLHEDRSVEKDSAVVSKLRS Sbjct: 181 AEASTRRFEQGNPISVLDGIFVTIKDDIDCLPHPTNGGTTWLHEDRSVEKDSAVVSKLRS 240 Query: 241 CGAILLGKANMHELGMGTTGNNSNYGTTRNPHDPKRYTGGSSSGSAAIVAAGLCSAALGT 300 CGAILLGKANMHELGMGTTGNNSNYGTTRNPHDPKRYTGGSSSGSAAIVAAGLCSAALGT Sbjct: 241 CGAILLGKANMHELGMGTTGNNSNYGTTRNPHDPKRYTGGSSSGSAAIVAAGLCSAALGT 300 Query: 301 DGGGSVRIPSALCGITGLKTTYGRTDMTGSLCEGGTVEIIGPLASSLEDAFLVYAAILGS 360 DGGGSVRIPSALCGITGLKTTYGRTDMTGSLCEGGTVEIIGPLASSLEDAFLVYAAILGS Sbjct: 301 DGGGSVRIPSALCGITGLKTTYGRTDMTGSLCEGGTVEIIGPLASSLEDAFLVYAAILGS 360 Query: 361 SSADRYNLKPSPPCFPKLLSHNGSNAIGSLRLGKYTKWFNDVSSSDISDKCEDILKLLSN 420 SSADRYNLKPSPPCFPKLLSHNGSNAIGSLRLGKYTKWFNDVSSSDISDKCEDILKLLSN Sbjct: 361 SSADRYNLKPSPPCFPKLLSHNGSNAIGSLRLGKYTKWFNDVSSSDISDKCEDILKLLSN 420 Query: 421 NHGCKVVEIVVPELEEMRAAHVISIGSPTLSSLTPYCEAGKNSKLSYDTRTSFAIFRSFS 480 NHGCKVVEIVVPELEEMRAAHVISIGSPTLSSLTPYCEAGKNSKLSYDTRTSFAIFRSFS Sbjct: 421 NHGCKVVEIVVPELEEMRAAHVISIGSPTLSSLTPYCEAGKNSKLSYDTRTSFAIFRSFS 480 Query: 481 ASDYIAAQCLRRRLMEYHLNIFKDVDVIVTPTTGMTAPVIPPDALKNGETNIQVTTDLMR 540 ASDYIAAQCLRRRLMEYHLNIFKDVDVIVTPTTGMTAPVIPPDALKNGETNIQVTTDLMR Sbjct: 481 ASDYIAAQCLRRRLMEYHLNIFKDVDVIVTPTTGMTAPVIPPDALKNGETNIQVTTDLMR 540 Query: 541 FVLAANLLGFPAISVPVGYDKEGLPIGLQIMGRPWAEATVLGLAAAVEELAPVTKKPAIF 600 FVLAANLLGFPAISVPVGYDKEGLPIGLQIMGRPWAEATVLGLAAAVEELAPVTKKPAIF Sbjct: 541 FVLAANLLGFPAISVPVGYDKEGLPIGLQIMGRPWAEATVLGLAAAVEELAPVTKKPAIF 600 Query: 601 YDILNTN 607 YDILNTN Sbjct: 601 YDILNTN 607 >2G5H-A nrPDB Length = 485 Score = 460 bits (1184), Expect = e-130, Method: Composition-based stats. Identities = 137/489 (28%), Positives = 212/489 (43%), Gaps = 42/489 (8%) Query: 125 SFRYWKIRDYAYAYRSKLTTPLQVAKRIISIIEEFGYDKPPTPFLIRFDANEVIKQAEAS 184 S RY + + + K P V K I IEE P + D IK+A+ Sbjct: 2 SIRYESVENLLTLIKDKKIKPSDVVKDIYDAIEE---TDPTIKSFLALDKENAIKKAQEL 58 Query: 185 TRRFEQGNPISVLDGIFVTIKDDIDCLPHPTNGGTTWLHEDRSVEKDSAVVSKLRSCGAI 244 + L GI + IKD+I T + L + +S V+ KL A+ Sbjct: 59 DELQAKDQMDGKLFGIPMGIKDNIITNGLETTCASKMLEGFVPI-YESTVMEKLHKENAV 117 Query: 245 LLGKANMHELGMGTTGNNSNYGTTRNPHDPKRYTGGSSSGSAAIVAAGLCSAALGTDGGG 304 L+GK NM E MG + S + T NP D K GGSS GSAA VAAGL +LG+D GG Sbjct: 118 LIGKLNMDEFAMGGSTETSYFKKTVNPFDHKAVPGGSSGGSAAAVAAGLVPLSLGSDTGG 177 Query: 305 SVRIPSALCGITGLKTTYGRTDMTGSLCEGGTVEIIGPLASSLEDAFLVYAAILGSSSAD 364 S+R P+A CG+ G+K TYGR G + +++ IGPL +++D +V AI G+ D Sbjct: 178 SIRQPAAYCGVVGMKPTYGRVSRFGLVAFASSLDQIGPLTRNVKDNAIVLEAISGADVND 237 Query: 365 RYNLKPSPPCFPKLLSHNGSNAIGSLRLGKYTKWFNDVSSSDISDKCEDILKLLSNNHGC 424 + P + I L++ ++ + + D+ + ++ ++ L + G Sbjct: 238 STSA----PVDDVDFTSEIGKDIKGLKVALPKEYLGEGVADDVKEAVQNAVETL-KSLGA 292 Query: 425 KVVEIVVPELEEMRAAHVISIGSPTLSSLTPY--CEAGKNSKLSYDTRT----------- 471 V E+ +P + ++ + S S+L+ + G +SK ++ Sbjct: 293 VVEEVSLPNTKFGIPSYYVIASSEASSNLSRFDGIRYGYHSKEAHSLEELYKMSRSEGFG 352 Query: 472 ----------SFAIFRSFSASDYIAAQCLRRRLMEYHLNIFKDVDVIVTPTTGMTAPVIP 521 +FA+ + + Y +Q +R + +F++ DV+V PT P Sbjct: 353 KEVKRRIFLGTFALSSGYYDAYYKKSQKVRTLIKNDFDKVFENYDVVVGPTA-------P 405 Query: 522 PDALKNGETNIQVTTDLMR--FVLAANLLGFPAISVPVGYDKEGLPIGLQIMGRPWAEAT 579 A GE T NL G P ISVP G G PIGLQ +G+P+ E T Sbjct: 406 TTAFNLGEEIDDPLTMYANDLLTTPVNLAGLPGISVPCG-QSNGRPIGLQFIGKPFDEKT 464 Query: 580 VLGLAAAVE 588 + +A E Sbjct: 465 LYRVAYQYE 473 >4WJ3-A nrPDB Length = 484 Score = 439 bits (1129), Expect = e-123, Method: Composition-based stats. Identities = 141/497 (28%), Positives = 234/497 (47%), Gaps = 44/497 (8%) Query: 130 KIRDYAYAYRSKLTTPLQVAKRIISIIEEFGYDKPPTPFLIRFDANEVIKQAEASTRRFE 189 + + A A K + ++ + ++ I + P I + I QA+A+ R Sbjct: 6 TLAEIARALADKQFSAEELTRTLLGRIRQL---DPQLNSFISITDDLAIAQAKAADERRA 62 Query: 190 QGNPISVLDGIFVTIKDDIDCLPHPTNGGTTWLHEDRSVEKDSAVVSKLRSCGAILLGKA 249 G ++L G + KD T+ G+ L S D+ VV KL + GA+ LGK Sbjct: 63 NGENGALL-GAPIAHKDLFCTQGVRTSCGSKMLDNFVS-PYDATVVEKLTAAGAVTLGKL 120 Query: 250 NMHELGMGTTGNNSNYGTTRNPHDPKRYTGGSSSGSAAIVAAGLCSAALGTDGGGSVRIP 309 NM E MG++ +S+YG +NP R GGSS GSAA VAA L AA GTD GGS+R P Sbjct: 121 NMDEFAMGSSNQSSHYGAVKNPWSLDRVPGGSSGGSAAAVAARLLPAATGTDTGGSIRQP 180 Query: 310 SALCGITGLKTTYGRTDMTGSLCEGGTVEIIGPLASSLEDAFLVYAAILGSSSADRYNLK 369 +AL +TG+K TYGR G + +++ GPLA + ED L+ + G D +++ Sbjct: 181 AALTNLTGIKPTYGRVSRWGMIAYASSLDQGGPLARTAEDCALMLGVMAGFDPKDSTSVE 240 Query: 370 PSPPCFPKLLSHNGSNAIGSLRLGKYTKWFNDVSSSDISDKCEDILKLLSNNHGCKVVEI 429 + L + LR+G ++F S I+D +++ L G V +I Sbjct: 241 QPVDDYLAALQ----KPLSGLRIGLPREYFGAGLDSRIADAVLAVVEEL-KTLGATVKDI 295 Query: 430 VVPELEEMRAAHVISIGSPTLSSLTPY--------CEAGKNSKLSYDTRT---------- 471 +P ++ A+ + + S+L+ + C+A +N + Y Sbjct: 296 SLPNMQHAIPAYYVIAPAEASSNLSRFDGVRYGYRCDAPQNLEDLYKRSRAEGFGSEVKN 355 Query: 472 -----SFAIFRSFSASDYIAAQCLRRRLMEYHLNIFKDVDVIVTPTTGMTAPVIPPDALK 526 ++A+ + + Y+ AQ +RR + ++ F +VDVI+ PTT A K Sbjct: 356 RIMVGTYALSAGYYDAYYLQAQKIRRLIKNDFVSAFAEVDVILGPTTPNPA-------WK 408 Query: 527 NGETNIQVTTDLMR--FVLAANLLGFPAISVPVGYDKEGLPIGLQIMGRPWAEATVLGLA 584 GE N + + + + ANL G P +S+P G+ +GLP+G+Q++ + E +L +A Sbjct: 409 IGEKNDDPVSQYLEDIYTITANLAGLPGLSMPAGF-VDGLPVGVQLLAPYFQEGRLLNVA 467 Query: 585 AAVEELAPV-TKKPAIF 600 ++++ T+ PA F Sbjct: 468 HQYQQVSDWHTRTPAGF 484 >3H0L-A nrPDB Length = 478 Score = 429 bits (1102), Expect = e-120, Method: Composition-based stats. Identities = 129/483 (26%), Positives = 216/483 (44%), Gaps = 44/483 (9%) Query: 130 KIRDYAYAYRSKLTTPLQVAKRIISIIEEFGYDKPPTPFLIRFDANEVIKQAEASTRRFE 189 + + + +P +V + + + I + +KQAE+ R Sbjct: 6 SLSELRELLKRGEVSPKEVVESFYDR---YNQTEEKVKAYITPLYGKALKQAESLKEREL 62 Query: 190 QGNPISVLDGIFVTIKDDIDCLPHPTNGGTTWLHEDRSVEKDSAVVSKLRSCGAILLGKA 249 L GI + +KD+I T + L D+ V+ +L+ GA+++GK Sbjct: 63 ------PLFGIPIAVKDNILVEGEKTTCASKILENFV-APYDATVIERLKKAGALIVGKT 115 Query: 250 NMHELGMGTTGNNSNYGTTRNPHDPKRYTGGSSSGSAAIVAAGLCSAALGTDGGGSVRIP 309 N+ E MG++ S + T+NP D +R GGSS GSAA VA +LG+D GGS+R P Sbjct: 116 NLDEFAMGSSTEYSAFFPTKNPWDLERVPGGSSGGSAASVAVLSAPVSLGSDTGGSIRQP 175 Query: 310 SALCGITGLKTTYGRTDMTGSLCEGGTVEIIGPLASSLEDAFLVYAAILGSSSADRYNLK 369 ++ CG+ G+K TYGR G + +++ IG ED LV I G D + K Sbjct: 176 ASFCGVIGIKPTYGRVSRYGLVAFASSLDQIGVFGRRTEDVALVLEVISGWDEKDSTSAK 235 Query: 370 PSPPCFPKLLSHNGSNAIGSLRLGKYTKWFNDVSSSDISDKCEDILKLLSNNHGCKVVEI 429 P + S + L++G ++F + + E+ +K L G ++ E+ Sbjct: 236 VPVPEW----SEEVKKEVKGLKIGLPKEFFEYELQPQVKEAFENFIKEL-EKEGFEIKEV 290 Query: 430 VVPELEEMRAAHVISIGSPTLSSLTPY--CEAGKNSKLSYDTRT---------------- 471 +P ++ + I S S+L Y G +K D Sbjct: 291 SLPHVKYSIPTYYIIAPSEASSNLARYDGVRYGYRAKEYKDIFEMYARTRDEGFGPEVKR 350 Query: 472 -----SFAIFRSFSASDYIAAQCLRRRLMEYHLNIFKDVDVIVTPTTGMTAPVIPPDALK 526 +FA+ + + Y+ AQ +RR + L F++VDVI +PTT P +P + Sbjct: 351 RIMLGTFALSAGYYDAYYLKAQKVRRLITNDFLKAFEEVDVIASPTT----PTLPFKFGE 406 Query: 527 NGETNIQVTTDLMRFVLAANLLGFPAISVPVGYDKEGLPIGLQIMGRPWAEATVLGLAAA 586 E I++ + + ANL G PAIS+P+ + +GLP+G Q++G+ W E T+L ++ Sbjct: 407 RLENPIEMYLSDI-LTVPANLAGLPAISIPIAWK-DGLPVGGQLIGKHWDETTLLQISYL 464 Query: 587 VEE 589 E+ Sbjct: 465 WEQ 467 >3AL0-A nrPDB Length = 475 Score = 397 bits (1019), Expect = e-111, Method: Composition-based stats. Identities = 135/493 (27%), Positives = 224/493 (45%), Gaps = 57/493 (11%) Query: 126 FRYWKIRDYAYAYRSKLTTPLQVAKRIISIIEEFGYDKPPTPFLIRFDANEVIKQAEAST 185 FR I + + Q++ I ++ P I N +++ Sbjct: 6 FRKLTIEECLKLSEEEREKLPQLSLETIKRLD------PHVKAFISVRENVSVEK----- 54 Query: 186 RRFEQGNPISVLDGIFVTIKDDIDCLPHPTNGGTTWLHEDRSVEKDSAVVSKLRSCGAIL 245 GI V IKD+I L T + L SV D+ VV K++ G ++ Sbjct: 55 --------KGKFWGIPVAIKDNILTLGMRTTCASRILENYESV-FDATVVKKMKEAGFVV 105 Query: 246 LGKANMHELGMGTTGNNSNYGTTRNPHDPKRYTGGSSSGSAAIVAAGLCSAALGTDGGGS 305 +GKAN+ E MG++ S + TRNP D +R GGSS GSAA V+AG+ AALG+D GGS Sbjct: 106 VGKANLDEFAMGSSTERSAFFPTRNPWDLERVPGGSSGGSAAAVSAGMVVAALGSDTGGS 165 Query: 306 VRIPSALCGITGLKTTYGRTDMTGSLCEGGTVEIIGPLASSLEDAFLVYAAILGSSSADR 365 VR P++LCG+ G K TYG G + +++ IGP+ ++ DA ++ I G D Sbjct: 166 VRQPASLCGVVGYKPTYGLVSRYGLVAFASSLDQIGPITKTVRDAAILMEIISGRDENDA 225 Query: 366 YNLKPSPPCFPKLLSHNGSNAIGSLRLGKYTKWFNDVSSSDISDKCEDILKLLSNNHGCK 425 + ++ + ++ + + +S++ E+ LKLL G K Sbjct: 226 TTVNRKVDFLSEI-----EEGVSGMKFAVPEEIYEHDIEEGVSERFEEALKLL-ERLGAK 279 Query: 426 VVEIVVPELEEMRAAHVISIGSPTLSSLTPY--CEAG---------------KNSKLSYD 468 V + +P ++ A + + + S+L + + G +N + Sbjct: 280 VERVKIPHIKYSVATYYVIAPAEASSNLARFDGVKYGLRIKEKGLREMYMKTRNVGFGEE 339 Query: 469 TRT-----SFAIFRSFSASDYIAAQCLRRRLMEYHLNIFKDVDVIVTPTTGMTAPVIPPD 523 R +F + ++ + + A +RR++ + + D I+TPT+ +TA Sbjct: 340 VRRRIMIGTFTLSAAYYEAYFNKAMKVRRKISDELNEVLSQYDAILTPTSPVTA------ 393 Query: 524 ALKNGETNIQVTTDLMR-FVLAANLLGFPAISVPVGYDKEGLPIGLQIMGRPWAEATVLG 582 K GE +T LM F + ANL G PAISVP G+ LP+G+Q++GR +A+ V Sbjct: 394 -FKIGEIKDPLTYYLMDIFTIPANLAGLPAISVPFGFSNN-LPVGVQVIGRRFADGKVFR 451 Query: 583 LAAAVEELAPVTK 595 +A A+E+ +P + Sbjct: 452 IARAIEKNSPYNE 464 >4YJI-A nrPDB Length = 495 Score = 396 bits (1018), Expect = e-110, Method: Composition-based stats. Identities = 129/498 (25%), Positives = 212/498 (42%), Gaps = 32/498 (6%) Query: 124 SSFRYWKIRDYAYAYRSKLTTPLQVAKRIISIIEEFGYDKPPTPFLIRFDA-NEVIKQAE 182 S + + +SK +P +V + I +IE+ + P + + A +E ++A Sbjct: 6 SPVHWKSAAEIVELVKSKQISPREVVESTIDLIEQ----RDPGLNAVVYKAYDEAREKAA 61 Query: 183 ASTRRFEQGNPISVLDGIFVTIKDDIDCLPH--PTNGGTTWLHEDRSVEKD-SAVVSKLR 239 A RR QG P+ +L G+ +KD P T GG L + R S K+ Sbjct: 62 ALERRIMQGEPVGMLAGVPTLMKDLFAAKPGWPSTLGGIRALKDARGAAGVWSTYPLKMS 121 Query: 240 SCGAILLGKANMHELGMGTTGNNSNYGTTRNPHDPKRYTGGSSSGSAAIVAAGLCSAALG 299 ++LLG+ N G T +N+ +G TRNP + GGSS G+AA+VA G+ A G Sbjct: 122 GEDSLLLGQTNSPVYGFRGTTDNTFFGPTRNPFNLDFNAGGSSGGAAALVADGIVPVAGG 181 Query: 300 TDGGGSVRIPSALCGITGLKTTYGRTDMTG--SLCEGGTVEIIGPLASSLEDAFLVYAAI 357 TDGGG++RIP+A G + + GR + G GP+ ++ DA L + Sbjct: 182 TDGGGAIRIPAAWTNTYGFQPSIGRVPFKSRPNAFHPGPYLYEGPITRTVRDAALAMNVL 241 Query: 358 LGSSSADRYNLKPSPPCFPKLLSHNGSNAIG-SLRLGKYTKWFNDVSSSDISDKCEDILK 416 G D +L+ L IG +L G + D+ K + Sbjct: 242 HGFDRRDPASLRVKLDFTSALAQGVRGKKIGLTLNYGVFPV---QQEIQDLIGKAARVFT 298 Query: 417 LLSNNHGCKVVEIVVP-ELEEMRAAHVISIGSPTLSSLTPYCEAGKNSKLSYDTRTSFAI 475 L + + V++ +P ++M A I PT++S+ + G + + A+ Sbjct: 299 ELGAH--VEFVDLGIPYSQKQMSDAWCRMIAIPTVASMQALRKEGIDLYGEHRADIPDAL 356 Query: 476 FRSFSASDYI------AAQCLRRRLMEYHLNIFKDVDVIVTPTTGMTAPVIPPDALKNGE 529 + A I A Q LR + + +F D+++ PT D G Sbjct: 357 MKWIDAVADISVQQISADQLLRTTVFDCMNGVFDRFDLLLAPTLACMPVRNATDGCTEGP 416 Query: 530 TNI--QVTTDLMRFVLA--ANLLGFPAISVPVGYDKEGLPIGLQIMGRPWAEATVLGLAA 585 + I + L+ + + N G P+ SVP G +GLP G+ I+G A+ V+ +A Sbjct: 417 SQINGEEIDPLIGWCMTYLTNFSGHPSASVPAGL-IDGLPAGMLIIGDRQADLDVIAASA 475 Query: 586 AVEELAPVTKKPAIFYDI 603 A E +P ++ +YDI Sbjct: 476 AFERASPWSQ----YYDI 489 >6C6G-A nrPDB Length = 457 Score = 387 bits (994), Expect = e-108, Method: Composition-based stats. Identities = 121/458 (26%), Positives = 198/458 (43%), Gaps = 24/458 (5%) Query: 138 YRSKLTTPLQVAKRIISIIEEFGYDKPPTPFLIRFDANEVIKQAEASTRRFEQGNPISVL 197 S T+ V + ++ I G +A+A R +G + L Sbjct: 10 IASGRTSARDVCEEALATI---GATDGLINAFTCRTVERARAEADAIDVRRARGEVLPPL 66 Query: 198 DGIFVTIKDDIDCLPHPTNGGTTWLHEDRSVEKDSAVVSKLRSCGAILLGKANMHELGMG 257 G+ +K+ D T G+ D+ +V +L++ GA+LLG NM E G Sbjct: 67 AGLPYAVKNLFDIEGVTTLAGSKINRTLPPARADAVLVQRLKAAGAVLLGGLNMDEFAYG 126 Query: 258 TTGNNSNYGTTRNPHDPKRYTGGSSSGSAAIVAAGLCSAALGTDGGGSVRIPSALCGITG 317 T N++YG TRNPHD R GGSS GS A +AAG +LG+D GS+R+P++LCG+ G Sbjct: 127 FTTENTHYGPTRNPHDTGRIAGGSSGGSGAAIAAGQVPLSLGSDTNGSIRVPASLCGVWG 186 Query: 318 LKTTYGRTDMTGSLCEGGTVEIIGPLASSLEDAFLVYAAILGSSSADRYNLKPSPPCFPK 377 LK T+GR G+ +++ +GPLA S+E L Y A+ G D Sbjct: 187 LKPTFGRLSRRGTYPFVHSIDHLGPLADSVEGLALAYDAMQGPDPLDPGCSASRIQPSVP 246 Query: 378 LLSHNGSNAIGSLRLGKYTKWFNDVSSSDISDKCEDILKLLSNNHGCKVVEIVVPELEEM 437 +LS I LR+G WF D + + L + ++ P+ E Sbjct: 247 VLS----QGIAGLRIGVLGGWFRDNAGPAARAAVDVAALTLGAS-----EVVMWPDAEIG 297 Query: 438 RAAHVISIGSPTLSSLTPYCEAGKNSKLSYDTRTSFAIFRSFSA-----SDYIAAQCLRR 492 RAA + S C + ++ ++ R S + Y+ AQ RR Sbjct: 298 RAAAFVITASE------GGCLHLDDLRIRPQDFEPLSVDRFISGVLQPVAWYLRAQRFRR 351 Query: 493 RLMEYHLNIFKDVDVIVTPTTGMTAPVIPPDALKNGETNIQVTTDLMRFVLAANLLGFPA 552 + +F+D D+++ P T ++AP I + ++ T + + G P Sbjct: 352 VYRDKVNALFRDWDILIAPATPISAPAIGTEWIEVNGTRHPCRPAMGLLTQPVSFAGCPV 411 Query: 553 ISVPVG-YDKEGLPIGLQIMGRPWAEATVLGLAAAVEE 589 ++ P + +G+PIG+Q++ PW E+ L +++ Sbjct: 412 VAAPTWPGENDGMPIGVQLIAAPWNESLCLRAGKVLQD 449 >5H6S-A nrPDB Length = 481 Score = 387 bits (994), Expect = e-108, Method: Composition-based stats. Identities = 128/463 (27%), Positives = 203/463 (43%), Gaps = 38/463 (8%) Query: 147 QVAKRIISIIEEFGYDKPPTPFLIRFDANEVIKQAEASTRRFEQGNPISVLDGIFVTIKD 206 +V + I+EF T + A++V+++A A+ R F LDG+ ++IKD Sbjct: 47 EVVHEHLDRIDEF---NALTNSFVELRADQVLEEARAADREFGS-TLGGPLDGVPLSIKD 102 Query: 207 DIDCLP-HPTNGGTTWLHEDRSVEKDSAVVSKLRSCGAILLGKANMHELGMGTTGNNSNY 265 H T+G ++ D +D ++LR+ G ++LG A + +L + + Y Sbjct: 103 SYSVAGLHRTDG--LPVNADVLDAQDDVATARLRAAGGLVLGHAGIPDLCIRWNSVSGLY 160 Query: 266 GTTRNPHDPKRYTGGSSSGSAAIVAAGLCSAALGTDGGGSVRIPSALCGITGLKTTYGRT 325 G RNP D R GGSS G AA VAAG + LG D GGS+R+P++ CG+ G +T GR Sbjct: 161 GAVRNPRDLSRTAGGSSGGDAANVAAGFATIGLGGDLGGSIRVPASWCGVYGFRTGPGRI 220 Query: 326 D---MTGSLCEGGTVE---IIGPLASSLEDAFLVYAAILGSSSADRYNLKPSPPCFPKLL 379 G +E IGP+A S++D L + + G DR + SP + Sbjct: 221 PDVNPNGGRSRNVVMELMAQIGPIARSIDDIELAFRIMTG---VDRRDTMSSPLGLIE-- 275 Query: 380 SHNGSNAIGSLRLGKYTKWFNDVSSSDISDKCEDILKLLSNNHGCKVVEIVVPELEEMRA 439 I + R+ V S + ++ + +++L G V E V+P+L Sbjct: 276 ------PIEAPRVAVLRHETGAVLDSSVEEQLDATIEML-RAEGYVVEENVLPDLHRAPE 328 Query: 440 AHVISIGSPTLSSLTP-YCEAGKNSKLSYDTRTSFAIFRSFSASDYIAAQCLRRRLMEYH 498 +G+ + + P E S+ + A Y+ A R + Sbjct: 329 VWAEIVGTELIHRVLPEVAELVIASERMHIVDMFGAYELGADVGAYLTALEERSSIQMTV 388 Query: 499 LNIFKDVDVIVTPTTGMTAPVIPPDALKNGETNIQVTTDLMRFVLAANLLGFPAISVPVG 558 + + +I+ P GM AP + D E +I + D MR V NLLG P+++ Sbjct: 389 AALMERYQLILAPVAGMPAPPLDFDDHIGREASIAL-FDQMRCVPWVNLLGLPSLA---- 443 Query: 559 YDKEGLPIGLQIMGRPWAEATVLGLAAAVEELAPVTK--KPAI 599 LP G+Q++GR E T+L A E AP + PAI Sbjct: 444 -----LPNGIQLVGRKHDELTILAAGRAYERRAPRVEIATPAI 481 >3KFU-E nrPDB Length = 471 Score = 379 bits (972), Expect = e-105, Method: Composition-based stats. Identities = 144/484 (29%), Positives = 221/484 (45%), Gaps = 47/484 (9%) Query: 142 LTTPLQVAKRIISIIEEFGYDKPPTPFLIRFDANEVIKQAEASTRRFEQGNPISVLDGIF 201 +PL+VA+ + ++E D FL ++++AEA P L G+ Sbjct: 14 EVSPLEVAQAYLKRVQEL--DPGLGAFLSL--NERLLEEAEAVD-------PGLPLAGLV 62 Query: 202 VTIKDDIDCLPHPTNGGTTWLHEDRSVEKDSAVVSKLRSCGAILLGKANMHELGMGTTGN 261 V +KD+I T G+ L ++ V++L++ GA++LGK N+ E GMG++ Sbjct: 63 VAVKDNIATRGLRTTAGSRLLENFVP-PYEATAVARLKALGALVLGKTNLDEFGMGSSTE 121 Query: 262 NSNYGTTRNPHDPKRYTGGSSSGSAAIVAAGLCSAALGTDGGGSVRIPSALCGITGLKTT 321 +S + T+NP DP R GGSS GSAA +AA L ALG+D GGSVR P+A CG+ GLK T Sbjct: 122 HSAFFPTKNPFDPDRVPGGSSGGSAAALAADLAPLALGSDTGGSVRQPAAFCGVYGLKPT 181 Query: 322 YGRTDMTGSLCEGGTVEIIGPLASSLEDAFLVYAAILGSSSADRYNLKPSPPCFPKLLSH 381 YGR G + +++ IGP+A S+ D L+ A G D +L P L Sbjct: 182 YGRVSRFGLIAYASSLDQIGPMARSVRDLALLMDAAAGPDPLDATSLDLPPRFQEAL--- 238 Query: 382 NGSNAIGSLRLGKYTKWFNDVSSSDISDKCEDILKLLSNNHGCKVVEIVVPELEEMRAAH 441 + LRLG + S + E+ LK+ G V E+ P L + AA+ Sbjct: 239 --EGPLPPLRLGVVREALAGN-SPGVERALEEALKVF-RELGLSVREVSWPSLPQALAAY 294 Query: 442 VISIGSPTLSSLTPY-------CEAGKNSKLSYDTRT--------------SFAIFRSFS 480 I + S+L Y AG+ + + +F + + Sbjct: 295 YILAPAEASSNLARYDGTLYGRRAAGEEVEGMMEATRALFGLEVKRRVLVGTFVLSSGYY 354 Query: 481 ASDYIAAQCLRRRLMEYHLNIFKDVDVIVTPTTGMTAPVIPPDALKNGETNIQVTTDLMR 540 + Y AQ RRRL +F++VD+++ PTT P P A ++ + Sbjct: 355 EAYYGRAQAFRRRLKAEAQALFREVDLLLLPTTP--HPAFPFGARRDPLAMYREDL---- 408 Query: 541 FVLAANLLGFPAISVPVGYDKEGLPIGLQIMGRPWAEATVLGLAAAVEELAPVTKKPAIF 600 + + ANL G PA+S P G++ LP+GLQ++ + +L A A EE A Sbjct: 409 YTVGANLTGLPALSFPAGFEGH-LPVGLQLLAPWGEDERLLRAALAFEEATARAHLKAPL 467 Query: 601 YDIL 604 + L Sbjct: 468 GEAL 471 >2DC0-A nrPDB Length = 434 Score = 373 bits (956), Expect = e-103, Method: Composition-based stats. Identities = 116/456 (25%), Positives = 187/456 (41%), Gaps = 30/456 (6%) Query: 137 AYRSKLTTPLQVAKRIISIIEEFGYDKPPTPFLIRFDANEVIKQAEASTRRFEQGNPISV 196 + TTPL + + + + F D+ +L D K+A A T +G Sbjct: 9 LLETGRTTPLALLEEALERAKAF-QDRNALAYL---DEEAARKEALALTEELRRGQVRGP 64 Query: 197 LDGIFVTIKDDIDCLPHPTNGGTTWLHEDRSVEKDSAVVSKLRSCGAILLGKANMHELGM 256 L G+ +T+KD PT GT + +++ V +LR GA+L K NMHE+ + Sbjct: 65 LHGLPLTVKDLFPVKGMPTRAGTKA--PLPPLPEEARAVRRLREAGALLFAKTNMHEIAL 122 Query: 257 GTTGNNSNYGTTRNPHDPKRYTGGSSSGSAAIVAAGLCSAALGTDGGGSVRIPSALCGIT 316 G TG N G RN DP R GGSS GSA VA G+ A+LGTD GGS+RIP+ G+ Sbjct: 123 GITGENPWTGPVRNAVDPSRQAGGSSGGSAVAVALGIGLASLGTDTGGSIRIPAGFNGVV 182 Query: 317 GLKTTYGRTDMTGSLCEGGTVEIIGPLASSLEDAFLVYAAILGSSSADRYNLKPSPPCFP 376 G K +YGR + G+L + + GPL S+ DA + + G Sbjct: 183 GFKPSYGRVSLEGALPLSRSTDHAGPLTRSVRDAHFLTEILAG----------------- 225 Query: 377 KLLSHNGSNAIGSLRLGKYTKWFNDVSSSDISDKCEDILKLLSNNHGCKVVEIVVPELEE 436 + + G + ++ +L+ L +V E+ +P LE Sbjct: 226 ---ESIPLEGVQNPVFGVPLDFLEGRLGVEVRKAFTRLLEDLPA-LRAEVREVSLP-LEG 280 Query: 437 MRAAHVISIGSPTLSSLTPYCEAGKNSKLSYDTRTSFAIFRSFSASDYIAAQCLRRRLME 496 + + + + + S R + + + DY A R L Sbjct: 281 VYEVYTRLVRYEA-ARIHEKALKEHPEGFSPQVREALLAGLALTEKDYRDAVAEREALRL 339 Query: 497 YHLNIFKDVDVIVTPTTGMTAPVIPPDALKNGETNIQVTTDLMRFVLAANLLGFPAISVP 556 + + VD ++ P + AP + + ++ + L +LLG P +++P Sbjct: 340 ELVKALRGVDALLLPVQPLPAPPLGTEEVELESGRKGHREAFITLTLPFSLLGVPTLALP 399 Query: 557 VGYDKEGLPIGLQIMGRPWAEATVLGLAAAVEELAP 592 EG+P+GLQ++G + VL L +E Sbjct: 400 FA-KVEGMPVGLQVVGAYGEDGKVLALGGWLEARLG 434 >3A1K-A nrPDB Length = 521 Score = 343 bits (880), Expect = 1e-94, Method: Composition-based stats. Identities = 126/436 (28%), Positives = 192/436 (44%), Gaps = 43/436 (9%) Query: 194 ISVLDGIFVTIKDDIDCLPHPTNGGTTWLHEDRSVEKDSAVVSKLRSCGAILLGKANMHE 253 VL G V IKD++ P G+ + E + +D+ VV++L + GA + GKA + Sbjct: 85 DGVLTGRRVAIKDNVTVAGVPMMNGSRTV-EGFTPSRDATVVTRLLAAGATVAGKAVCED 143 Query: 254 LGMGTTGNNSNYGTTRNPHDPKRYTGGSSSGSAAIVAAGLCSAALGTDGGGSVRIPSALC 313 L + G RNP D +R GGSS GSAA+VA G A+G D GGS+RIP+A C Sbjct: 144 LCFSGSSFTPASGPVRNPWDRQREAGGSSGGSAALVANGDVDFAIGGDQGGSIRIPAAFC 203 Query: 314 GITGLKTTYGRTDMTGSLCEGGTVEIIGPLASSLEDAFLVYAAILGSSSADRYNLKPSPP 373 G+ G K T+G TG+ T++ +GP+ ++ DA L+ + I G D Sbjct: 204 GVVGHKPTFGLVPYTGAFPIERTIDHLGPITRTVHDAALMLSVIAGRDGNDPRQADSVEA 263 Query: 374 CFPKLLSHNGSNAIGSLRLGKYTKWF-NDVSSSDISDKCEDILKLLSNNHGCKVVEIVVP 432 LS S+ G LR+G + F + VS ++ D L+ GC V E+ +P Sbjct: 264 G--DYLSTLDSDVDG-LRIGIVREGFGHAVSQPEVDDAVRAAAHSLTE-IGCTVEEVNIP 319 Query: 433 ELEEMRAAHVISI-----GSPTLSSLTPYCEAGKNSKLSYDTR--TSFAIFR-------- 477 + A H+ ++ G+ + Y G N++ YD FA R Sbjct: 320 --WHLHAFHIWNVIATDGGAYQMLDGNGY---GMNAEGLYDPELMAHFASRRIQHADALS 374 Query: 478 ---------------SFSASDYIAAQCLRRRLMEYHLNIFKDVDVIVTPTTGMTAPVIPP 522 + + Y A+ L + + DV+V PT A +P Sbjct: 375 ETVKLVALTGHHGITTLGGASYGKARNLVPLARAAYDTALRQFDVLVMPTLPYVASELPA 434 Query: 523 DALKNGETNIQVTTDLMRFVLAANLLGFPAISVPVGYDKEGLPIGLQIMGRPWAEATVLG 582 + T I ++ ++ G P++SVP G GLP+G+ I GR + +ATVL Sbjct: 435 KDVDRA-TFITKALGMIANTAPFDVTGHPSLSVPAGL-VNGLPVGMMITGRHFDDATVLR 492 Query: 583 LAAAVEELAPVTKKPA 598 + A E+L PA Sbjct: 493 VGRAFEKLRGAFPTPA 508 >4N0I-A nrPDB Length = 464 Score = 316 bits (810), Expect = 2e-86, Method: Composition-based stats. Identities = 107/429 (24%), Positives = 183/429 (42%), Gaps = 47/429 (10%) Query: 197 LDGIFVTIKDDIDCLPHPTNGGTTWLHEDRSVEKDSAVVSKLRSCGAILLGKANMHELGM 256 L G +IKD+I PT + L +S D+ VV L+ G +LGK N+ E GM Sbjct: 44 LTGCVASIKDNIVTKDFPTTCASHILENFKS-PFDATVVKLLKQAGVHILGKTNLDEFGM 102 Query: 257 GTTGNNSNYGTTRNP---HDPKRYTGGSSSGSAAIVAAGLCSAALGTDGGGSVRIPSALC 313 G+ G +S G NP H+ K+ GGSSSG+AA VA L ALGTD GGSVR+P+ Sbjct: 103 GSGGVHSIRGPVINPLYPHEDKKIMGGSSSGAAASVACDLVDFALGTDTGGSVRLPACYG 162 Query: 314 GITGLKTTYGRTDMTGSLCEGGTVEIIGPLASSLEDAFLVYAAILGSSSADRYNLKPSPP 373 + G K +YGR G + +++ +G L+ + V+ + D +L Sbjct: 163 SVLGFKPSYGRLSRFGVIAYSQSLDTVGILSKKINVLRKVFHTLDKYDMKDPTSL----S 218 Query: 374 CFPKLLSHNGSNAIGSLRLGKYTKWFNDVSSSDISDKCEDILKLLSNNHGCKVVEIVVPE 433 + L L++G ++ ++ +L+ L N G ++ + +P Sbjct: 219 VELRELIEGNKKVRRPLKVGIVKEFSHESMPIGFHRLYLSLLEKLI-NLGLEIYPVSIPS 277 Query: 434 LEEMRAAHVISIGSPTLSSLTPY--CEAGK--------NSKLSYDTRTSFAIF------- 476 ++ + + S+L+ Y G + L TR+ F Sbjct: 278 VKNCLPIYYTLSPAEAASNLSRYDGIRYGYRDSELDIKDGILFAPTRSKFGTEVKNRIIL 337 Query: 477 ------RSFSASDYIAAQCLRRRLMEYHLNIFKDVDVIVTPT---TGMTAPVIPPD---- 523 +++I A+ LR L++ IF+ +V+ G+ ++P Sbjct: 338 GNYNLCSDAFKNNFIKAEKLRVNLIDEFDGIFRFPNVLTNSKGNPDGLDLLIVPTSSKLP 397 Query: 524 ----ALKNGETNIQVTTDLMR-FVLAANLLGFPAISVPVGYDKEGLPIGLQIMGRPWAEA 578 + E + + F + +L G P++S+P+ KE PIGLQ++G+ ++ Sbjct: 398 GSIRDFEEEEAKSPANSYINDVFTVPMSLAGLPSLSMPL---KEKTPIGLQVVGQYGDDS 454 Query: 579 TVLGLAAAV 587 TVL ++ Sbjct: 455 TVLDFVESI 463 >4GYR-A nrPDB Length = 621 Score = 311 bits (796), Expect = 6e-85, Method: Composition-based stats. Identities = 116/450 (25%), Positives = 197/450 (43%), Gaps = 30/450 (6%) Query: 147 QVAKRIISIIEEFGYDKPPTPFLIRFDANEVIKQAEASTRRFEQGNPISVLDGIFVTIKD 206 QV I +G ++ EV+ +A A G P L G+ +KD Sbjct: 51 QVVTEAYDRITRYG---DKAVWIALRPREEVLAEARALDASPATGKP---LYGVPFAVKD 104 Query: 207 DIDCLPHPTNGGTTWLHEDRSVEKDSAVVSKLRSCGAILLGKANMHELGMGTTGNNSNYG 266 +ID P + ++D+ VV++LR+ GAI+LGK N+ + G G S +G Sbjct: 105 NIDVAGLPCSAACPAFT--YEPDRDATVVARLRAAGAIVLGKTNLDQFATGLVGTRSPFG 162 Query: 267 TTRNPHDPKRYTGGSSSGSAAIVAAGLCSAALGTDGGGSVRIPSALCGITGLKTTYGRTD 326 R D +GGSSSGSA VAAGL + +LGTD GS R+P+A + G+K T G Sbjct: 163 APRCVFDQDYISGGSSSGSAVAVAAGLVAFSLGTDTAGSGRVPAAFNNLVGVKPTKGLLS 222 Query: 327 MTGSLCEGGTVEIIGPLASSLEDAFLVYAAILGSSSADRYNLKPSPPCFPKLLSHNGSNA 386 +G + +++ + A+S+ + L+ G +AD Y S P + L H G Sbjct: 223 TSGVVPACRSLDCVTVFAASVAEGTLIRRIAEGYDAADPY----SRPSQKRRLPHVGLR- 277 Query: 387 IGSLRLGKYTKWFNDVSSSDISDKCEDILKLLSNNHGCKVVEIVVPELEEMRAAHVISIG 446 +G R + + N ++ ++++ + ++VEI + R A + G Sbjct: 278 VGVPRQDQREFYGNTAYAALYQRALDEMI-----SLDAELVEI---DFAPFRDAAKLLYG 329 Query: 447 SPTLSS-LTPYCEAGKNSKLSYD--TRTSFAIFRSFSASDYIAAQCLRRRLMEYHLNIFK 503 P ++ L + + S+D R+ ++ SA D Q L + + Sbjct: 330 GPWVAERLEAVGDHLSRAPDSFDPVVRSIVETAKTLSAVDAFRGQYELAALTQQANAQWA 389 Query: 504 DVDVIVTPTTGMTAPVIPPDALKNGETNIQVTTDLMRFVLAANLLGFPAISVPVGYDKEG 563 +D+++ PT AP I + +++ + L + NLL AI+VP G+ + G Sbjct: 390 RMDILLLPT----APTIHKVEAVMADP-VRLNSQLGHYTNFVNLLDCAAIAVPAGFIETG 444 Query: 564 LPIGLQIMGRPW-AEATVLGLAAAVEELAP 592 LP G+ ++G + ++ L L P Sbjct: 445 LPFGVTLVGPAFSDDSMALIADRLHRRLEP 474 >3A2Q-A nrPDB Length = 493 Score = 310 bits (795), Expect = 8e-85, Method: Composition-based stats. Identities = 120/492 (24%), Positives = 195/492 (39%), Gaps = 47/492 (9%) Query: 135 AYAYRSKLTTPLQVAKRIISIIEEFGYDKPPTPFLIRFDANEVIKQAEASTRRFEQGNPI 194 A RS + ++ + I+ ++ P +I + +++E ++ Sbjct: 14 AELVRSGEISRTELLEATIAHVQAV---NPEINAVIIPLFEKARRESELAS--------- 61 Query: 195 SVLDGIFVTIKDDIDCL--PHPTNGGTTWLHEDRSVEKDSAVVSKLRSCGAILLGKANMH 252 G+ +KD T+ + D+ V ++R+ G +LLGK N Sbjct: 62 GPFAGVPYLLKDLTVVSQGDINTSSIKGMKESGYRADHDAYFVQRMRAAGFVLLGKTNTP 121 Query: 253 ELGMGTTGNNSNYGTTRNPHDPKRYTGGSSSGSAAIVAAGLCSAALGTDGGGSVRIPSAL 312 E+G T +G TRNP + R GGSS GS A VAA L A G D G+VRIP+++ Sbjct: 122 EMGNQVTTEPEAWGATRNPWNLGRSVGGSSGGSGAAVAAALSPVAHGNDAAGAVRIPASV 181 Query: 313 CGITGLKTTYGRTDM----TGSLCEGGTVEIIGPLASSLEDAFLVYAAILGSSSADRYNL 368 CG+ GLK T GR T S G G A S+ D + + G D + Sbjct: 182 CGVVGLKPTRGRISPGPLVTDSDNVAGAA-HEGLFARSVRDIAALLDVVSGHRPGDTFCA 240 Query: 369 KPSPPCFPKLLSHNGSNAIGSLRLGKYTKWFNDVSSSDISDKCEDILKLLSNNHGCKVVE 428 + + + +S N GSLR+G T N V + +C + + + Sbjct: 241 PTASRPYAQGISENP----GSLRVGVLTH--NPVGDFALDPECAAAARGAAAALAALGHD 294 Query: 429 IVVPELEEMRAAHVISIGSPTLSSLTPYCEAGKNSKL-------------SYDT--RTSF 473 + E + + S T+ + E +N +L S++ R Sbjct: 295 VNDAYPEALGDRSFLKDYS-TICDVAIAREIERNGELIGRPLTEDDVEWTSWEMVKRADQ 353 Query: 474 AIFRSFSAS----DYIAAQCLRRRLMEYHLNIFKDVDVIVTPTTGMTAPVIPPDALKNGE 529 R+F+A Y A + R + L I V TP G D Sbjct: 354 VTGRAFAACVDELRYYAGKVERWWEAGWDLLILPTV-TRQTPEIGELMLAKGTDLEGRQS 412 Query: 530 TNIQVTTDLMRFVLAANLLGFPAISVPVGYDKEGLPIGLQIMGRPWAEATVLGLAAAVEE 589 I + ++ F + N+ G PAIS+P+G +G+PIG+QI+ E +L +AA +E Sbjct: 413 AFISGSLQMLAFTVPFNVSGQPAISLPIGMSSDGMPIGVQIVAAYGREDLLLQVAAQLEG 472 Query: 590 LAPV-TKKPAIF 600 P ++P + Sbjct: 473 ALPWVARRPQLL 484 >1O9P-A nrPDB Length = 414 Score = 303 bits (776), Expect = 1e-82, Method: Composition-based stats. Identities = 109/444 (24%), Positives = 168/444 (37%), Gaps = 45/444 (10%) Query: 153 ISIIEEFGYDKPPTPFLIRFDANEVIKQ---AEASTRRFEQGNPISVLDGIFVTIKDDID 209 + E G P A E ++ A + + L GI V IKD ID Sbjct: 7 LQRRIETGELSPNAAIAQSHAAIEAREKEVHAFVRHDKSARAQASGPLRGIAVGIKDIID 66 Query: 210 CLPHPTNGGTTWLHEDRSVEKDSAVVSKLRSCGAILLGKANMHELGMGTTGNNSNYGTTR 269 PT G+ + D+ VV L+ GA ++GK + + T Sbjct: 67 TANMPTEMGSEI-YRGWQPRSDAPVVMMLKRAGATIIGKTTTTAFA------SRDPTATL 119 Query: 270 NPHDPKRYTGGSSSGSAAIVAAGLCSAALGTDGGGSVRIPSALCGITGLKTTYGRTDMTG 329 NPH+ GG+SSGSAA V AG+ ALGT GGSV P+A CG +K ++ G Sbjct: 120 NPHNTGHSPGGASSGSAAAVGAGMIPLALGTQTGGSVIRPAAYCGTAAIKPSFRMLPTVG 179 Query: 330 SLCEGGTVEIIGPLASSLEDAFLVYAAILGSSSADRYNLKPSPPCFPKLLSHNGSNAIGS 389 C ++ +G + ED A+ G S +P Sbjct: 180 VKCYSWALDTVGLFGARAEDLARGLLAMTGRSEFSGIVPAKAP----------------- 222 Query: 390 LRLGKYTKWFNDVSSSDISDKCEDILKLLSNNHGCKVVEIVVPEL--EEMRAAHVISIGS 447 R+G + F + +K + G V I +PE E R +I Sbjct: 223 -RIGVVRQEFAGAVEPAAEQGLQAAIK-AAERAGASVQAIDLPEAVHEAWRIHPIIQDFE 280 Query: 448 PTLSSLTPYCEAGKNSKLSYDTRTSFAIFRSFSASDYIAAQCLRRRLMEYHLNIFKDVDV 507 + + E + +++ R S + +Y A+ + RR +F+ VDV Sbjct: 281 AHRALAWEFSEH--HDEIAPMLRASLDATVGLTPKEYDEARRIGRRGRRELGEVFEGVDV 338 Query: 508 IVTPTTGMTAPVIPPDALKNGETNIQVTTDLMRFVLAANLLGFPAISVPVGYDKEGLPIG 567 ++T + TAP +T R+ L+G P ++VPV GLPIG Sbjct: 339 LLTYSAPGTAP-----------AKALASTGDPRYNRLWTLMGNPCVNVPV-LKVGGLPIG 386 Query: 568 LQIMGRPWAEATVLGLAAAVEELA 591 +Q++ R +A L A +E+ Sbjct: 387 VQVIARFGNDAHALATAWFLEDAL 410 >6MRG-A nrPDB Length = 580 Score = 178 bits (452), Expect = 4e-45, Method: Composition-based stats. Identities = 115/521 (22%), Positives = 175/521 (33%), Gaps = 87/521 (16%) Query: 138 YRSKLTTPLQVAKRIISIIEEFGYDKPPTPFLIRFDANEVIKQAEASTRRFEQGNPISVL 197 +S +P V + E + D + QA QG +L Sbjct: 87 LQSGELSPEAVFFTYLGKAWEVNKGTNCVTSYLT-DCETQLSQA------PRQG----LL 135 Query: 198 DGIFVTIKDDIDCLPHPTNGGTTWLHEDRSVEKDSAVVSKLRSCGAILLGKANMHELGMG 257 G+ V++K+ H + G + L+E E D VV L+ GA+ N+ + Sbjct: 136 YGVPVSLKECFSYKGHDSTLGLS-LNEGMPSESDCVVVQVLKLQGAVPFVHTNVPQSMFS 194 Query: 258 TTGNNSNYGTTRNPHDPKRYTGGSSSGSAAIVAAGLCSAALGTDGGGSVRIPSALCGITG 317 +N +G T NP + GGSS G A++ +G LGTD GGS+R PSA CGI G Sbjct: 195 YDCSNPLFGQTMNPWKSSKSPGGSSGGEGALIGSGGSPLGLGTDIGGSIRFPSAFCGICG 254 Query: 318 LKTTYGRTDMTGSL-CEGGTVEI---IGPLASSLEDAFLVYAAILGSSSADRYNLKPSPP 373 LK T R +G C G + +GP+A +E L A + L P+ P Sbjct: 255 LKPTGNRLSKSGLKGCVYGQTAVQLSLGPMARDVESLALCLKA---LLCEHLFTLDPTVP 311 Query: 374 CFPKLLSHNGSNAIGSLRLGKYTKWFNDVSSSDISDKCEDILKLLSNNHGCKV--VEIVV 431 + LR+G Y + S + + + L + + + Sbjct: 312 PL--PFREEVYRSSRPLRVGYYETDNYTMPSPAMRRALIETKQRLEAAGHTLIPFLPNNI 369 Query: 432 PELEEMRAA---------HVISIGS-----PTLSSLTPYCEAGK---------NSKLSYD 468 P E+ + + P L L L Sbjct: 370 PYALEVLSTGGLFSDGGRSFLQNFKGDFVDPCLGDLILILRLPSWFKRLLSLLLKPLFPR 429 Query: 469 TRTSFAIFRSFSASDYIAAQCLRRRLMEYHLNIFKDV--DVIVTPTTGMTAPVIPPDALK 526 R SA Q + + +K + DV++TP G A + Sbjct: 430 LAAFLNNMRPRSAEKLWKLQHEIEMYRQSVIAQWKAMNLDVLLTPMLG-PALDLNTPGR- 487 Query: 527 NGETNIQVTTDLMRFVLAANLLGFPAISVPV---------------GYDKE--------- 562 T + + + N L FPA VPV GY + Sbjct: 488 --------ATGAVSYTMLYNCLDFPAGVVPVTTVTAEDDAQMELYKGYFGDIWDIILKKA 539 Query: 563 -----GLPIGLQIMGRPWAEATVLGLAAAVEELAPVTKKPA 598 GLP+ +Q + PW E L VE+L K+P+ Sbjct: 540 MKNSVGLPVAVQCVALPWQEELCLRFMREVEQLMTPQKQPS 580 >4DPQ-A nrPDB Length = 360 Score = 34.4 bits (77), Expect = 0.14, Method: Composition-based stats. Identities = 29/140 (20%), Positives = 50/140 (35%), Gaps = 13/140 (9%) Query: 206 DDIDCLPHPTNGGTTWLHEDR--SVEKDSAV-VSKLRSCGAILLGKANMHELGMGTTGNN 262 DDI L T T +L + R D V + +++G M + Sbjct: 56 DDIKALRVITAIKTPYLPDGRFDLEAYDDLVNIQIQNGAEGVIVGGTTGEGQLMSWDEHI 115 Query: 263 SNYGTTRNPHDPKRYTGGSSSGSAAIVAAGLCSAALGTDGGGSVRIPSALCGITGLKTTY 322 G T N G++ ++ A T+ G +V + +AL + Y Sbjct: 116 MLIGHTVNCFGGSIKVIGNTGSNSTREAI------HATEQGFAVGMHAAL----HINPYY 165 Query: 323 GRTDMTGSLCEGGTVEIIGP 342 G+T + G + +V +GP Sbjct: 166 GKTSIEGLIAHFQSVLHMGP 185 >6C44-A nrPDB Length = 104 Score = 33.3 bits (74), Expect = 0.35, Method: Composition-based stats. Identities = 16/80 (20%), Positives = 25/80 (31%), Gaps = 19/80 (23%) Query: 303 GGSVRIPS----------------ALCGITGLKTTYGRTDMTGSLCEGGTVEIIGPLASS 346 GG R+P+ A T +K + G + GS+ + +EII Sbjct: 28 GGLKRLPAGLLLGHGPIRMVLAILAFLRFTAIKPSLGLINRWGSVGKKEAMEIIKKFKK- 86 Query: 347 LEDAFLVYAAILGSSSADRY 366 D + I R Sbjct: 87 --DLAAMLRIINARKEKKRR 104 >3TUU-A nrPDB Length = 346 Score = 32.9 bits (73), Expect = 0.40, Method: Composition-based stats. Identities = 29/140 (20%), Positives = 52/140 (37%), Gaps = 13/140 (9%) Query: 206 DDIDCLPHPTNGGTTWLHEDR--SVEKDSAV-VSKLRSCGAILLGKANMHELGMGTTGNN 262 DDI L T T +L + R D+ V + + +++G M + Sbjct: 42 DDIKSLRLITAIKTPYLPDGRFDLEAYDALVNMQIVDGAEGVIVGGTTGEGQLMSWDEHI 101 Query: 263 SNYGTTRNPHDPKRYTGGSSSGSAAIVAAGLCSAALGTDGGGSVRIPSALCGITGLKTTY 322 G T N G++ ++ A T+ G +V + +AL + Y Sbjct: 102 MLIGHTVNCFGGSIKVIGNTGSNSTREAI------HATEQGFAVGMHAAL----HINPYY 151 Query: 323 GRTDMTGSLCEGGTVEIIGP 342 G+T + G + +V +GP Sbjct: 152 GKTSLEGLVSHFESVLPMGP 171 >3JS4-A nrPDB Length = 227 Score = 32.5 bits (72), Expect = 0.60, Method: Composition-based stats. Identities = 11/75 (14%), Positives = 27/75 (36%) Query: 436 EMRAAHVISIGSPTLSSLTPYCEAGKNSKLSYDTRTSFAIFRSFSASDYIAAQCLRRRLM 495 + + V + +L A +S L + A + + Y+ LR++ + Sbjct: 145 QFGSGWVWLVYDEDAKALKVVSTANADSPLLTQGQLPLATMDVWEHAYYLDYLNLRKKYI 204 Query: 496 EYHLNIFKDVDVIVT 510 + L + D ++ Sbjct: 205 DVFLEHLLNWDFVLG 219 >3D8F-A nrPDB Length = 148 Score = 32.1 bits (71), Expect = 0.77, Method: Composition-based stats. Identities = 23/73 (31%), Positives = 32/73 (43%), Gaps = 10/73 (13%) Query: 93 GEDESPIDRLETALKCLPQYDPSRSLHADPVSSFRYWKI-------RDYAYAYRSKLTTP 145 GE + + +LE L + LHA P+ S R W + RD+AY R KLT Sbjct: 52 GEGKDLLLQLEDETLKLVEPQSQALLHAQPIISIRVWGVGRDSGRERDFAYVARDKLT-- 109 Query: 146 LQVAKRIISIIEE 158 Q+ K + E Sbjct: 110 -QMLKCHVFRCEA 121 >5Z0R-A nrPDB Length = 445 Score = 32.1 bits (71), Expect = 0.78, Method: Composition-based stats. Identities = 38/208 (18%), Positives = 62/208 (29%), Gaps = 51/208 (24%) Query: 190 QGNPISVLDGIFVTIKDDIDCLPHPTNGGTTWLHEDRSVEKDSAVVSKLRSCGAILLGKA 249 +G P G+ ID +L ++ V+K + GA+ L K+ Sbjct: 252 KGQPSKPFVGVLSA---GIDAASPNKELAKEFLENYLLTDEGLEAVNKDKPLGAVAL-KS 307 Query: 250 NMHELG----MGTTGNNSNYGTTRNPHDPKRYTGGSSSGSAAIVAAGLCSAALGTDG--- 302 EL + T N+ G P+ P+ V + +AA G Sbjct: 308 YEEELAKDPRIAATMENAQKGEIM-PNIPQMSA------FWYAVRTAVINAASGRQTVDE 360 Query: 303 --------------GGSVRIPS----------------ALCGITGLKTTYGRTDMTGSLC 332 GG R+P+ A T +K + G + GS+ Sbjct: 361 ALKDAQTRITVSPFGGLKRLPAGLLLGHGPIRMVLAILAFLRFTAIKPSLGLINRWGSVG 420 Query: 333 EGGTVEIIGPLASSLEDAFLVYAAILGS 360 + +EII D + I Sbjct: 421 KKEAMEIIKKFKK---DLAAMLRIINAR 445 >5YGH-A nrPDB Length = 76 Score = 31.7 bits (70), Expect = 0.92, Method: Composition-based stats. Identities = 15/74 (20%), Positives = 24/74 (32%), Gaps = 19/74 (25%) Query: 303 GGSVRIPS----------------ALCGITGLKTTYGRTDMTGSLCEGGTVEIIGPLASS 346 GG R+P+ A T +K + G + GS+ + +EII Sbjct: 6 GGLKRLPAGLLLGHGPIRMVLAILAFLRFTAIKPSLGLINRWGSVGKKEAMEIIKKFKK- 64 Query: 347 LEDAFLVYAAILGS 360 D + I Sbjct: 65 --DLAAMLRIINAR 76 >3GOA-A nrPDB Length = 387 Score = 31.7 bits (70), Expect = 0.97, Method: Composition-based stats. Identities = 23/154 (14%), Positives = 46/154 (29%), Gaps = 16/154 (10%) Query: 181 AEASTRRFEQGNPISVLDGIFVTIKDDIDCLPH-----PTNGGTTWLHEDRSVEKDSAVV 235 A+A+ +S L GI ++D H T G + D+ V Sbjct: 141 AKAAGMMGLTAEMLSRLHGISREMQDQFAARSHARAWAATQSGAFKTEIIPTGGHDADGV 200 Query: 236 SKLRSCGAILLGKANMHELGMGTTGNNSNYGTTRNPHDPKRYTGGSSSGSAAIVAAGLCS 295 K + ++ + + L + + + S +A +V + + Sbjct: 201 LKQFNYDEVIRPETTVEAL----STLRPAFDPVSGTVTAGTSSALSDGAAAMLVMSESRA 256 Query: 296 AALGTDGGGSVRIPSALCGITGLKTT---YGRTD 326 LG +R + + G + YG Sbjct: 257 RELGLKPRARIRSMA----VVGCDPSIMGYGPVP 286 >5GMX-A nrPDB Length = 398 Score = 31.3 bits (69), Expect = 1.2, Method: Composition-based stats. Identities = 20/127 (15%), Positives = 33/127 (25%), Gaps = 7/127 (5%) Query: 191 GNPISVLDGIFVTIKDDIDCLPHPTNGGTTWLHEDRSVEKDSAVVSKL-----RSCGAIL 245 G + G ++ G + +D V L G L Sbjct: 170 GEVARRVTGRTKSLGQLFAEKVASPIGAGNDYYIGLPASEDHRVAEMLPVIGSEQLGTGL 229 Query: 246 LGKANMHELGMGTTGNNSNYGTTRN--PHDPKRYTGGSSSGSAAIVAAGLCSAALGTDGG 303 GK M + + N G + G+ +A + A G G Sbjct: 230 GGKKRMSDALYCAMAHPPLTAHIANDRAWRAAEVPGANGQGNGRGIAKVYGALANGGTLG 289 Query: 304 GSVRIPS 310 G+ I + Sbjct: 290 GTRIISA 296 >2GAG-A nrPDB Length = 965 Score = 31.3 bits (69), Expect = 1.2, Method: Composition-based stats. Identities = 21/93 (22%), Positives = 36/93 (38%), Gaps = 11/93 (11%) Query: 225 DRSVEKDSAVVSKLRSCGAILLGKANMHELGMGTTGNNSNYGTTRNPHDPKRYTGGSSSG 284 +++D V LR+ GA GM + + Y + +D + +G ++ G Sbjct: 483 FVDLQRDQTVADVLRATGA-----------GMKSVEHIKRYTSISTANDQGKTSGVAAIG 531 Query: 285 SAAIVAAGLCSAALGTDGGGSVRIPSALCGITG 317 A V AA+GT + P A + G Sbjct: 532 VIAAVLGIENPAAIGTTTFRAPYTPVAFAALAG 564 >2OWM-A nrPDB Length = 443 Score = 30.9 bits (68), Expect = 1.7, Method: Composition-based stats. Identities = 29/249 (11%), Positives = 74/249 (29%), Gaps = 18/249 (7%) Query: 322 YGRTDMTGSLCEGGTVEIIGPLASSLEDAFLVYAAILGSSSADRYNLKPSPPCFPKLLSH 381 YG+T S GT + G + + ED L + F H Sbjct: 143 YGQTGSGKSYTMMGTPDQPGLIPRTCED--LFQRIASAQDETPNISYNVKVSYFEVYNEH 200 Query: 382 NGSNAIGSLRLGKYTKWFNDVSSSDISDKCEDILKLLSNNHGCKVVEIVVPELEEMRAAH 441 + + + K + S +D+ ++ + + + + A+ Sbjct: 201 VR-DLLAPVVPNKPPYYLKVRESPTEGPYVKDLTEVPVRGLEEIIRWMRIGDGSRTVAST 259 Query: 442 VISIGSPTLSSLTPYCEAGKN--------SKLSYDTRTSFAIFRSFSASDYIAAQCLR-- 491 ++ S ++ + ++ S R + S Q LR Sbjct: 260 KMNDTSSRSHAVFTIMLKQIHHDLETDDTTERSSRIRLVDLAGSERAKSTEATGQRLREG 319 Query: 492 RRLMEYHLNIFKDVDVIVTPTTGMTAPVIPPDALKN-----GETNIQVTTDLMRFVLAAN 546 + + + + + + P + + P P + + + + ++ ++L + Sbjct: 320 SNINKSLTTLGRVIAALADPKSSASRPSSPVKSGRGRTPGPANSVVPYRDSVLTWLLKDS 379 Query: 547 LLGFPAISV 555 L G ++ Sbjct: 380 LGGNSKTAM 388 >4XWT-A nrPDB Length = 559 Score = 30.2 bits (66), Expect = 2.7, Method: Composition-based stats. Identities = 28/159 (17%), Positives = 52/159 (32%), Gaps = 18/159 (11%) Query: 126 FRYWKIRDYAYAYRSKLTTPLQVAKRIISIIEEFGYDKPPTPFLIRFDANEVIKQAEAST 185 +R I D A+ ++ + + + G+ PP PFL + E+ Q Sbjct: 250 YRIQNILDLAHRQGRRVVMEGRSMIKYAQAAQATGHMNPPEPFLTSEEVGELQDQQVLFV 309 Query: 186 RRFEQGNPISVLDGIFVTIKDDIDCLPHPTNGGTTWLHEDRSVEKDSA--VVSKLRSCGA 243 QG P++VL + I T ++ +D+ +V++L G Sbjct: 310 CTGSQGQPMAVLGRLAFGTHAKIALRRGDTVILSS---NPIPGNEDAVNLIVNRLYEIGV 366 Query: 244 ILL----------GKANMHELGMGTTGNNSNYGTTRNPH 272 ++ G A+ EL + P Sbjct: 367 DVVYPPTYRVHASGHASQEELATILNLTRPKFFL---PW 402 >2E5V-A nrPDB Length = 472 Score = 30.2 bits (66), Expect = 2.8, Method: Composition-based stats. Identities = 13/46 (28%), Positives = 18/46 (39%), Gaps = 7/46 (15%) Query: 274 PKRYTGGSS----SGSAAIVAAGLCSAALGTDGGGSVRIPSALCGI 315 KR GGS+ G AA V + D +R+ LC + Sbjct: 29 SKRIDGGSTPIAKGGVAASVGSDDSPELHAQDT---IRVGDGLCDV 71 >5L9W-B nrPDB Length = 732 Score = 30.2 bits (66), Expect = 3.0, Method: Composition-based stats. Identities = 29/188 (15%), Positives = 61/188 (32%), Gaps = 19/188 (10%) Query: 145 PLQVAKRIISIIEEFGYDKPPTPFLIRFDANEVIKQAEAS-TRRFEQGNPISVLDGIFVT 203 P+ ++ ++S I E Y++ T L + + A+ + +G G F+ Sbjct: 210 PVVMSHSVVSKIGE--YERTMTAVLDAYLQRSMQNDIGATWDKLRAKG-----YHGAFLM 262 Query: 204 IKDDIDCLPHPTNGGTTWLHEDRSVE--KDSAVVSKLRSCGAIL--LGKANMHE-LGMGT 258 I + + + + +KL + +G + L + + Sbjct: 263 IHNSGGSADIFKTPASRTFNGGPVAGLMGSAYFANKLGYKNVVAGDVGGTSFDVALVVES 322 Query: 259 TGNNSNYGTTRNPHD-----PKRYTGGSSSGSAAIVAAGLCSAALGTDGGGSVRIPSALC 313 + N + + + + GS GS A V +G GS+ P Sbjct: 323 SVRNYTFRPVIDKWMVNVTMMQTISVGSGGGSIAKVDRSGTRLEVGPRSAGSMPGPVCY- 381 Query: 314 GITGLKTT 321 + G + T Sbjct: 382 DLGGTEPT 389 >5VKU-h nrPDB Length = 306 Score = 29.8 bits (65), Expect = 3.6, Method: Composition-based stats. Identities = 20/108 (18%), Positives = 38/108 (35%), Gaps = 4/108 (3%) Query: 172 FDANEVIKQAEASTRRFEQGNPISVLDGIFVTIKDDIDCLPHPTNGGTTWLHEDRSVEKD 231 F + ++ +A+ ++ + I + D + T + + + + E Sbjct: 156 FSLDRSYEEVKAAVQQLQTITFRDATFTIPDPVIDQHLLIDMKTACLSMSMVANLASELT 215 Query: 232 SAVVSKLRSCG-AILLGKANMHELGMGTTGNNSNYGTTRNPHDPKRYT 278 V KL ++LL K EL M S G R P P+ + Sbjct: 216 MTYVRKLALEDSSMLLVK--CQELLMRLDRERSV-GEPRTPARPQHVS 260 >4HJH-A nrPDB Length = 481 Score = 29.4 bits (64), Expect = 4.3, Method: Composition-based stats. Identities = 31/171 (18%), Positives = 52/171 (30%), Gaps = 17/171 (9%) Query: 376 PKLLSHNGSNAIGSLRLGKYTKWFNDVSSSDISDKCEDILKLLSNNHGCKVVEIVVPELE 435 + G ++ LR+G Y SS D +L L V + + + Sbjct: 165 DRYAGFLGKGSLNGLRVGVYQH------SSVARDLLMYLLTTLG------VEPVALGRSD 212 Query: 436 EMRAAHVISIGSPTLSSLTPYCEAGKNSKLSYDTRTSFAIFRSFSASDYIAAQCLRRRLM 495 ++ ++ L + GK+ +L T R A ++ Q +R L Sbjct: 213 IFVPVDTEALRPEDIALLA---QWGKSDRLDAIVSTDGDADRPLIADEH--GQFVRGDLA 267 Query: 496 EYHLNIFKDVDVIVTPTTGMTAPVIPPDALKNGETNIQVTTDLMRFVLAAN 546 + D +VTP T TA + M V N Sbjct: 268 GAITATWVGADTLVTPVTSNTALESRFPKVLRTRVGSPYVIASMAQVSTGN 318 >1VRQ-A nrPDB Length = 964 Score = 29.4 bits (64), Expect = 4.4, Method: Composition-based stats. Identities = 19/100 (19%), Positives = 36/100 (36%), Gaps = 11/100 (11%) Query: 218 GTTWLHEDRSVEKDSAVVSKLRSCGAILLGKANMHELGMGTTGNNSNYGTTRNPHDPKRY 277 + +++D V LR+ GA GM + + Y + +D + Sbjct: 475 AVHYKFHFVDLQRDQTVADVLRATGA-----------GMQSVEHIKRYTSISTANDQGKT 523 Query: 278 TGGSSSGSAAIVAAGLCSAALGTDGGGSVRIPSALCGITG 317 +G ++ G A V A +GT + P + + G Sbjct: 524 SGVAAIGVIAAVLGIENPAQIGTTTFRAPYTPVSFAALAG 563 >2FB9-A nrPDB Length = 322 Score = 29.4 bits (64), Expect = 4.7, Method: Composition-based stats. Identities = 20/101 (19%), Positives = 33/101 (32%), Gaps = 7/101 (6%) Query: 153 ISIIEEFGYDKPPTPFLIRFDANEVIKQAEASTRRFEQGNPISVLDGIFVTIKDD----- 207 IS +E F + R+D V+++A + R E G + + G + + Sbjct: 166 ISRVERFQDLEAALALAFRYDEKAVVEKALSPVRELEVG-VLGNVFGEASPVGEVRYEAP 224 Query: 208 -IDCLPHPTNGGTTWLHEDRSVEKDSAVVSKLRSCGAILLG 247 D T G L V +L +LG Sbjct: 225 FYDYETKYTPGRAELLIPAPLDPGTQETVQELALKAYKVLG 265 >2IOU-G nrPDB Length = 535 Score = 29.4 bits (64), Expect = 5.1, Method: Composition-based stats. Identities = 43/315 (13%), Positives = 83/315 (26%), Gaps = 46/315 (14%) Query: 150 KRIISIIEEFGYDKPPTPFLIRFDANEVIKQAEASTRRFEQGNPISVLDGIFVTIKDDID 209 ++ + + D ++ A QA + + + V G VT++ Sbjct: 90 HATLANVSDTRDDDGIALYVAGEQA-----QASIADSTLQGAGGVRVERGANVTVQRSTI 144 Query: 210 CLPHPTNGGTTWLHEDRSVEKDSAVVSKLRSCGAILLGKANMHEL-GMGTTGNNSNYGTT 268 G L + ++LG ++ + G S +G Sbjct: 145 VDGGLHIGTLQPLQPEDLPPSR------------VVLGDTSVTAVPASGAPAAVSVFGAN 192 Query: 269 RNPHDPKRYTGGSSSGSAAIVAA-----------GLCSAALGTDGGGSV---RIPSALCG 314 D TGG ++G AA+ A G A G GG+V +P Sbjct: 193 ELTVDGGHITGGRAAGVAAMDGAIVHLQRATIRRGDAP-AGGAVPGGAVPGGAVPGGFGP 251 Query: 315 ITGLKTTYGRTDMTGSLCEGGTVEIIGPLASSLEDAFLVYAAILGSS-----------SA 363 + L YG ++ ++ L +++ + G S Sbjct: 252 L--LDGWYGVDVSDSTVDLAQSIVEAPQLGAAIRAGRGARVTVSGGSLSAPHGNVIETGG 309 Query: 364 DRYNLKPSPPCFPKLLSHNGSNAIGSLRLGKYTKWFNDVSSSDISDKCEDILKLLSNNHG 423 P L +L + + + + + L G Sbjct: 310 GARRFPPPASPLSITLQAGARAQGRALLYRVLPEPVKLTLAGGAQGQGDIVATELPPIPG 369 Query: 424 CKVVEIVVPELEEMR 438 + V + R Sbjct: 370 ASSGPLDVALASQAR 384 >3TKT-A nrPDB Length = 450 Score = 29.4 bits (64), Expect = 5.3, Method: Composition-based stats. Identities = 15/70 (21%), Positives = 27/70 (38%), Gaps = 1/70 (1%) Query: 145 PLQVAKRIISIIEEFGYDKPPTPFLIRFDANEVIKQAEASTRRFEQGNPISVLDGIFVTI 204 P +V + +I + +G +P A + + A E +S DG+ Sbjct: 28 PAEVGRAVIDP-KSYGTWEPLLDRFDALRAEAPVAKVVAPDDEHEPFWLVSSFDGVMKAS 86 Query: 205 KDDIDCLPHP 214 KD+ L +P Sbjct: 87 KDNATFLNNP 96 >4WJI-A nrPDB Length = 293 Score = 29.0 bits (63), Expect = 5.7, Method: Composition-based stats. Identities = 14/33 (42%), Positives = 17/33 (51%), Gaps = 3/33 (9%) Query: 277 YTGGSSSGSAAIVAAGLCSAALGTDGG---GSV 306 G+S AA +AA L A+ TD G GSV Sbjct: 72 VPVGASGAVAAEIAAHLKPGAIVTDVGSTKGSV 104 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.306 0.121 0.304 Lambda K H 0.267 0.0377 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 20,623,226 Number of Sequences: 36641 Number of extensions: 844878 Number of successful extensions: 2573 Number of sequences better than 10.0: 48 Number of HSP's better than 10.0 without gapping: 38 Number of HSP's successfully gapped in prelim test: 37 Number of HSP's that attempted gapping in prelim test: 2409 Number of HSP's gapped (non-prelim): 86 length of query: 607 length of database: 10,336,785 effective HSP length: 103 effective length of query: 504 effective length of database: 6,562,762 effective search space: 3307632048 effective search space used: 3307632048 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 62 (28.6 bits)