BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q76EQ0 (333 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 3L6C-A nrPDB 671 0.0 5X2L-A nrPDB 634 0.0 5CVC-A nrPDB 263 9e-71 5YBW-A nrPDB 232 2e-61 1V71-A nrPDB 197 5e-51 1VE5-A nrPDB 186 1e-47 2GN1-A nrPDB 148 3e-36 3IAU-A nrPDB 137 6e-33 1TDJ-A nrPDB 122 2e-28 1PWH-A nrPDB 74 1e-13 5JJC-A nrPDB 70 9e-13 1M54-A nrPDB 67 9e-12 4COO-A nrPDB 67 1e-11 5MMS-A nrPDB 67 1e-11 6NMX-A nrPDB 62 3e-10 3PC3-A nrPDB 59 2e-09 4H27-A nrPDB 59 3e-09 3FCA-A nrPDB 59 4e-09 2RKB-A nrPDB 55 5e-08 2D1F-A nrPDB 54 7e-08 5D84-A nrPDB 53 2e-07 5C3U-A nrPDB 52 4e-07 6C2H-A nrPDB 52 5e-07 5OHX-A nrPDB 51 8e-07 5YGR-A nrPDB 50 1e-06 2Q3D-A nrPDB 50 2e-06 5I7O-A nrPDB 49 4e-06 2PQM-A nrPDB 47 9e-06 5B1I-A nrPDB 47 1e-05 2ZSJ-A nrPDB 47 1e-05 2BHS-A nrPDB 46 2e-05 2JC3-A nrPDB 46 2e-05 1UIN-A nrPDB 46 2e-05 4I1Y-A nrPDB 45 5e-05 2EFY-A nrPDB 45 5e-05 4OFX-A nrPDB 44 1e-04 4LMA-A nrPDB 43 2e-04 5B55-A nrPDB 42 3e-04 6AHI-A nrPDB 40 0.001 4D9G-A nrPDB 40 0.002 5J5V-A nrPDB 40 0.002 5XW3-A nrPDB 39 0.002 2EGU-A nrPDB 39 0.003 3VBE-A nrPDB 39 0.004 2ISQ-A nrPDB 37 0.011 3X43-A nrPDB 36 0.018 5XA2-A nrPDB 36 0.020 5XCN-X nrPDB 36 0.023 5KIN-B nrPDB 35 0.033 5OCW-B nrPDB 35 0.060 5XEM-A nrPDB 33 0.12 5EY5-B nrPDB 33 0.15 4LMB-A nrPDB 33 0.20 4AEC-A nrPDB 32 0.29 1X1Q-A nrPDB 32 0.41 4ZW2-A nrPDB 30 1.5 3T4P-A nrPDB 30 1.9 5BPF-A nrPDB 29 2.3 1NKU-A nrPDB 29 2.3 6DQP-A nrPDB 29 3.0 6AMI-A nrPDB 28 5.0 2DZD-A nrPDB 28 7.0 4AJN-A nrPDB 27 8.4 >3L6C-A nrPDB Length = 339 Score = 671 bits (1732), Expect = 0.0, Method: Compositional matrix adjust. Identities = 331/333 (99%), Positives = 331/333 (99%) Query: 1 MCAQYCISFADVEKAHLNIQDSVHLTPVLTSSILNQIAGRNLFFKCELFQKTGSFKIRGA 60 M AQY ISFADVEKAHLNIQDSVHLTPVLTSSILNQIAGRNLFFKCELFQKTGSFKIRGA Sbjct: 1 MDAQYDISFADVEKAHLNIQDSVHLTPVLTSSILNQIAGRNLFFKCELFQKTGSFKIRGA 60 Query: 61 LNAIRGLIPDTLEGKPKAVVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPNCKKLAIQA 120 LNAIRGLIPDTLEGKPKAVVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPNCKKLAIQA Sbjct: 61 LNAIRGLIPDTLEGKPKAVVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPNCKKLAIQA 120 Query: 121 YGASIVYSEPSDESRENVAQRIIQETEGILVHPNQEPAVIAGQGTIALEVLNQVPLVDAL 180 YGASIVYSEPSDESRENVAQRIIQETEGILVHPNQEPAVIAGQGTIALEVLNQVPLVDAL Sbjct: 121 YGASIVYSEPSDESRENVAQRIIQETEGILVHPNQEPAVIAGQGTIALEVLNQVPLVDAL 180 Query: 181 VVPVGGGGMVAGIAITIKTLKPSVKVYAAEPSNADDCYQSKLKGELTPNLHPPETIADGV 240 VVPVGGGGMVAGIAITIKTLKPSVKVYAAEPSNADDCYQSKLKGELTPNLHPPETIADGV Sbjct: 181 VVPVGGGGMVAGIAITIKTLKPSVKVYAAEPSNADDCYQSKLKGELTPNLHPPETIADGV 240 Query: 241 KSSIGLNTWPIIRDLVDDVFTVTEDEIKYATQLVWERMKLLIEPTAGVGLAAVLSQHFQT 300 KSSIGLNTWPIIRDLVDDVFTVTEDEIKYATQLVWERMKLLIEPTAGVGLAAVLSQHFQT Sbjct: 241 KSSIGLNTWPIIRDLVDDVFTVTEDEIKYATQLVWERMKLLIEPTAGVGLAAVLSQHFQT 300 Query: 301 VSPEVKNICIVLSGGNVDLTSLSWVKQAERPAP 333 VSPEVKNICIVLSGGNVDLTSLSWVKQAERPAP Sbjct: 301 VSPEVKNICIVLSGGNVDLTSLSWVKQAERPAP 333 >5X2L-A nrPDB Length = 348 Score = 634 bits (1636), Expect = 0.0, Method: Compositional matrix adjust. Identities = 304/333 (91%), Positives = 323/333 (96%), Gaps = 1/333 (0%) Query: 1 MCAQYCISFADVEKAHLNIQDSVHLTPVLTSSILNQIAGRNLFFKCELFQKTGSFKIRGA 60 MCAQYCISFADVEKAH+NI+DS+HLTPVLTSSILNQ+ GRNLFFKCELFQKTGSFKIRGA Sbjct: 1 MCAQYCISFADVEKAHINIRDSIHLTPVLTSSILNQLTGRNLFFKCELFQKTGSFKIRGA 60 Query: 61 LNAIRGLIPDTLEGKPKAVVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPNCKKLAIQA 120 LNA+R L+PD LE KPKAVVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAP+CKKLAIQA Sbjct: 61 LNAVRSLVPDALERKPKAVVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPDCKKLAIQA 120 Query: 121 YGASIVYSEPSDESRENVAQRIIQETEGILVHPNQEPAVIAGQGTIALEVLNQVPLVDAL 180 YGASIVY EPSDESRENVA+R+ +ETEGI+VHPNQEPAVIAGQGTIALEVLNQVPLVDAL Sbjct: 121 YGASIVYCEPSDESRENVAKRVTEETEGIMVHPNQEPAVIAGQGTIALEVLNQVPLVDAL 180 Query: 181 VVPVGGGGMVAGIAITIKTLKPSVKVYAAEPSNADDCYQSKLKGELTPNLHPPETIADGV 240 VVPVGGGGM+AGIAIT+K LKPSVKVYAAEPSNADDCYQSKLKG+L PNL+PPETIADGV Sbjct: 181 VVPVGGGGMLAGIAITVKALKPSVKVYAAEPSNADDCYQSKLKGKLMPNLYPPETIADGV 240 Query: 241 KSSIGLNTWPIIRDLVDDVFTVTEDEIKYATQLVWERMKLLIEPTAGVGLAAVLSQHFQT 300 KSSIGLNTWPIIRDLVDD+FTVTEDEIK ATQLVWERMKLLIEPTAGVG+AAVLSQHFQT Sbjct: 241 KSSIGLNTWPIIRDLVDDIFTVTEDEIKCATQLVWERMKLLIEPTAGVGVAAVLSQHFQT 300 Query: 301 VSPEVKNICIVLSGGNVDLT-SLSWVKQAERPA 332 VSPEVKNICIVLSGGNVDLT S++WVKQAERPA Sbjct: 301 VSPEVKNICIVLSGGNVDLTSSITWVKQAERPA 333 >5CVC-A nrPDB Length = 346 Score = 263 bits (671), Expect = 9e-71, Method: Compositional matrix adjust. Identities = 146/320 (45%), Positives = 212/320 (66%), Gaps = 6/320 (1%) Query: 5 YCISFADVEKAHLNIQDSVHLTPVLTSSILNQIAGRNLFFKCELFQKTGSFKIRGALNAI 64 Y + +A I VH TPV++S+ ++ + G+ LFFKCE FQK G+FKIRGA N+I Sbjct: 16 YAADIDSIREAQARIAPYVHRTPVMSSTSIDAMVGKKLFFKCECFQKAGAFKIRGASNSI 75 Query: 65 RGLIPDTLEGKPKAVVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPNCKKLAIQAYGAS 124 L + + K VVTHSSGNH A+ AAKL GIPA+IV+P+ AP K ++ YG Sbjct: 76 FALDDEQVS---KGVVTHSSGNHAAAVALAAKLRGIPAHIVIPRNAPASKVENVKCYGGH 132 Query: 125 IVYSEPSDESRENVAQRIIQETEGILVHPNQEPAVIAGQGTIALEVLNQVPLVDALVVPV 184 I++S+ S ESRE V++R+ +ET +L+HP I+GQGT++LE+L QVP +D ++VP+ Sbjct: 133 IIWSDASIESREYVSKRVQEETGAVLIHPINSKYTISGQGTVSLELLEQVPEIDTIIVPI 192 Query: 185 GGGGMVAGIAITIKTLKPSVKVYAAEPSNADDCYQSKLKGELTPNLHPPETIADGVKSSI 244 GGG+++G+A+ K + PS+++ AAEP ADD QSK G++ L TIADG+++ + Sbjct: 193 SGGGLISGVALAAKAINPSIRILAAEPKGADDSAQSKAAGKII-TLPSTNTIADGLRAFL 251 Query: 245 GLNTWPIIRDLVDDVFTVTEDEIKYATQLVWERMKLLIEPTAGVGLAAVLSQHFQTVSP- 303 G TWP++RDLVDDV V + I A ++ +E +K+ +EP+ +GLAA LS F+ S Sbjct: 252 GDLTWPVVRDLVDDVIVVDDTAIVDAMKMCYEILKVAVEPSGAIGLAAALSDEFKQSSAW 311 Query: 304 -EVKNICIVLSGGNVDLTSL 322 E I I++SGGNVDL +L Sbjct: 312 HESSKIGIIVSGGNVDLGTL 331 >5YBW-A nrPDB Length = 329 Score = 232 bits (592), Expect = 2e-61, Method: Compositional matrix adjust. Identities = 143/334 (42%), Positives = 198/334 (59%), Gaps = 21/334 (6%) Query: 4 QYCISFADVEKAHLNIQDSVHLTPVLTSSILNQI----AGRNLFFKCELFQKTGSFKIRG 59 Q+ ++ D++KA+ I + TPV TS +++ AGR +FK E QKTGSFK RG Sbjct: 3 QFEVTVTDIKKAYDRISKHILYTPVFTSPTFDRMVGSKAGRQFYFKAENLQKTGSFKARG 62 Query: 60 ALNAIRGLIPDTLEGKPK--AVVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPNCKKLA 117 ALNAI LE +P VVTHSSGNHGQAL +A+K G+ +VVP+TAP K A Sbjct: 63 ALNAILC----ALEREPSLAGVVTHSSGNHGQALAWASKRAGVKCCVVVPKTAPQVKFDA 118 Query: 118 IQAYGASIVYSEPSDESRENVAQRIIQETEGILVHPNQEPAVIAGQGTIALEVLNQVPLV 177 ++ YGA +V EP+ SR+ + + + + + + VIAGQGTIALE+L Q P + Sbjct: 119 MENYGAEVVKCEPNPTSRKETCEGLAKSRGYKYISSSDDYDVIAGQGTIALELLQQQPDL 178 Query: 178 DALVVPVGGGGMVAGIAITIKTLKPSVKVYAAEPSNA--DDCYQSKLKGELTPNLHPP-- 233 DA++V V GGM +GI + K K +KV+ EP ++C + + L PN PP Sbjct: 179 DAILVSVSAGGMASGICVYTKNTKSDLKVFLVEPEGKMLEECISKRER--LWPN--PPQF 234 Query: 234 -ETIADG-VKSSIGLNTWPIIRDLVD-DVFTVTEDEIKYATQLVWERMKLLIEPTAGVGL 290 +TIADG + G TWPII +L + +V TV D I A + V+ RMKL+IE AG + Sbjct: 235 LDTIADGIILQQCGNKTWPIILELPEKEVITVNNDNIVEAMRFVFARMKLVIEAAAGATV 294 Query: 291 AAVLSQHFQTVSPEVKNICIVLSGGNVDLTSLSW 324 AA +++ FQ PE K + I+L GGNVD+ L W Sbjct: 295 AAAMTERFQNFHPEAKKVGIILCGGNVDIEKLPW 328 >1V71-A nrPDB Length = 323 Score = 197 bits (501), Expect = 5e-51, Method: Compositional matrix adjust. Identities = 128/317 (40%), Positives = 194/317 (61%), Gaps = 16/317 (5%) Query: 8 SFADVEKAHLNIQDSVHLTPVLTSSILNQIAGRNLFFKCELFQKTGSFKIRGALNAIRGL 67 ++ DV A I+ + TPVLTSS +N+ +FFKCE FQK G+FK RGALNA+ L Sbjct: 9 TYDDVASASERIKKFANKTPVLTSSTVNKEFVAEVFFKCENFQKMGAFKFRGALNALSQL 68 Query: 68 IPDTLEGKPKA-VVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPNCKKLAIQAYGASIV 126 E + KA V+T SSGNH QA+ +AK+ GIPA I++P AP K A + YG ++ Sbjct: 69 N----EAQRKAGVLTFSSGNHAQAIALSAKILGIPAKIIMPLDAPEAKVAATKGYGGQVI 124 Query: 127 YSEPSDESRENVAQRIIQETEGI-LVHPNQEPAVIAGQGTIALEVLNQVPLVDALVVPVG 185 + + RE +A+ I E EG+ ++ P P V+AGQGT A E+ +V +DAL V +G Sbjct: 125 MYDRYKDDREKMAKE-ISEREGLTIIPPYDHPHVLAGQGTAAKELFEEVGPLDALFVCLG 183 Query: 186 GGGMVAGIAITIKTLKPSVKVYAAEPSNADDCYQSKLKGELTPNLHPPETIADGVKSS-I 244 GGG+++G A+ + P+ +VY EP +D QS KG + ++ P+TIADG ++ + Sbjct: 184 GGGLLSGSALAARHFAPNCEVYGVEPEAGNDGQQSFRKGSIV-HIDTPKTIADGAQTQHL 242 Query: 245 GLNTWPIIRDLVDDVFTVTEDEIKYATQLVWERMKLLIEPTAGVGLAAVLSQHFQTVSPE 304 G T+ II++ VDD+ TV+++E+ + RMK+++EPT + AA + + + Sbjct: 243 GNYTFSIIKEKVDDILTVSDEELIDCLKFYAARMKIVVEPTGCLSFAAA-----RAMKEK 297 Query: 305 VKN--ICIVLSGGNVDL 319 +KN I I++SGGNVD+ Sbjct: 298 LKNKRIGIIISGGNVDI 314 >1VE5-A nrPDB Length = 311 Score = 186 bits (471), Expect = 1e-47, Method: Compositional matrix adjust. Identities = 129/318 (40%), Positives = 189/318 (59%), Gaps = 15/318 (4%) Query: 8 SFADVEKAHLNIQDSVHLTPVLTSSILNQIAGRNLFFKCELFQKTGSFKIRGALNAIRGL 67 S D+ A I H TP+LTS +L+ + G+ L K E QKTGSFK RGAL+ L Sbjct: 3 SLQDLYAAFRRIAPYTHRTPLLTSRLLDGLLGKRLLLKAEHLQKTGSFKARGALSKALAL 62 Query: 68 IPDTLEGKPKAVVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPNCKKLAIQAYGASIVY 127 PK ++ SSGNH Q + YAA++ G+ A +V+P+ A KK +AYGA +V Sbjct: 63 ------ENPKGLLAVSSGNHAQGVAYAAQVLGVKALVVMPEDASPYKKACARAYGAEVVD 116 Query: 128 SEPSDESRENVAQRIIQETEGILVHPNQEPAVIAGQGTIALEVLNQVPLV----DALVVP 183 + ++RE VA+ + +ET L+HP +P VIAGQGT LE+L Q + A++ P Sbjct: 117 RGVTAKNREEVARALQEETGYALIHPFDDPLVIAGQGTAGLELLAQAGRMGVFPGAVLAP 176 Query: 184 VGGGGMVAGIAITIKTLKPSVKVYAAEPSNADDCYQSKLKGELTPNLHPPETIADGVKS- 242 VGGGG++AG+A +K L P+ V EP ADD +S G + PP T ADGV++ Sbjct: 177 VGGGGLLAGLATAVKALSPTTLVLGVEPEAADDAKRSLEAGRILRLEAPPRTRADGVRTL 236 Query: 243 SIGLNTWPIIRDLVDDVFTVTEDEIKYATQLVWERMKLLIEPTAGVGLAAVLSQHFQTVS 302 S+G T+PI+R+ VD + TV+E+ + A +L++ R K ++EPT + LAAVL +H + Sbjct: 237 SLGERTFPILRERVDGILTVSEEALLEAERLLFTRTKQVVEPTGALPLAAVL-EHGARLP 295 Query: 303 PEVKNICIVLSGGNVDLT 320 + + ++LSGGN D + Sbjct: 296 ---QTLALLLSGGNRDFS 310 >2GN1-A nrPDB Length = 342 Score = 148 bits (374), Expect = 3e-36, Method: Compositional matrix adjust. Identities = 116/322 (36%), Positives = 184/322 (57%), Gaps = 10/322 (3%) Query: 7 ISFADVEKAHLNIQDSVHLTPVLTSSILNQIAGRNLFFKCELFQKTGSFKIRGALNAIRG 66 ++ D+ +A + ++ T + S+ ++ +F K E Q+TGSFKIRGA N + Sbjct: 22 VAIEDILEAKKRLAGKIYKTGMPRSNYFSERCKGEIFLKFENMQRTGSFKIRGAFNKLSS 81 Query: 67 LIPDTLEGKPKAVVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPNCKKLAIQAYGASIV 126 L T K K VV S+GNH Q ++ + + GI +V+P+ AP K A Y A +V Sbjct: 82 L---TEAEKRKGVVACSAGNHAQGVSLSCAMLGIDGKVVMPKGAPKSKVAATCDYSAEVV 138 Query: 127 -YSEPSDESRENVAQRIIQETEG-ILVHPNQEPAVIAGQGTIALEVLNQVPLVDALVVPV 184 + + +++ V++ I ETEG I + P +P VIAGQGTI LE++ + VD ++VP+ Sbjct: 139 LHGDNFNDTIAKVSE--IVETEGRIFIPPYDDPKVIAGQGTIGLEIMEDLYDVDNVIVPI 196 Query: 185 GGGGMVAGIAITIKTLKPSVKVYAAEPSNADDCYQSKLKGELTPNLHPPETIADGVK-SS 243 GGGG++AGIAI IK++ P++KV + N S GE+T + T+ADG S Sbjct: 197 GGGGLIAGIAIAIKSINPTIKVIGVQAENVHGMAASYYTGEITTH-RTTGTLADGCDVSR 255 Query: 244 IGLNTWPIIRDLVDDVFTVTEDEIKYATQLVWERMKLLIEPTAGVGLAAVLSQHFQTVSP 303 G T+ I+R+LVDD+ V+EDEI+ + + +R K++ E + AA+LS + Sbjct: 256 PGNLTYEIVRELVDDIVLVSEDEIRNSMIALIQRNKVITEGAGALACAALLSGKLDSHIQ 315 Query: 304 EVKNICIVLSGGNVDLTSLSWV 325 K + I+ SGGN+DL+ +S + Sbjct: 316 NRKTVSII-SGGNIDLSRVSQI 336 >3IAU-A nrPDB Length = 366 Score = 137 bits (345), Expect = 6e-33, Method: Compositional matrix adjust. Identities = 97/305 (31%), Positives = 161/305 (52%), Gaps = 10/305 (3%) Query: 26 TPVLTSSILNQIAGRNLFFKCELFQKTGSFKIRGALNAIRGLIPDTLEGKPKAVVTHSSG 85 +P+ + L+ G N + K E Q+ SFK+RGA N + L + L+ K V+T S+G Sbjct: 61 SPLELAEKLSDRLGVNFYIKREDKQRVFSFKLRGAYNMMSNLSREELD---KGVITASAG 117 Query: 86 NHGQALTYAAKLEGIPAYIVVPQTAPNCKKLAIQAYGASIV-YSEPSDESRENVAQRIIQ 144 NH Q + A + A IV+P T P K A++A G +V Y + DE++ + + + Sbjct: 118 NHAQGVALAGQRLNCVAKIVMPTTTPQIKIDAVRALGGDVVLYGKTFDEAQTHALE--LS 175 Query: 145 ETEGI-LVHPNQEPAVIAGQGTIALEVLNQVPLVDALVVPVGGGGMVAGIAITIKTLKPS 203 E +G+ + P +P VI GQGTI E+ Q+ + A+ +PVGGGG++AG+A K + P+ Sbjct: 176 EKDGLKYIPPFDDPGVIKGQGTIGTEINRQLKDIHAVFIPVGGGGLIAGVATFFKQIAPN 235 Query: 204 VKVYAAEPSNADDCYQSKLKGELTPNLHPPETIADGVKSS-IGLNTWPIIRDLVDDVFTV 262 K+ EP A S +G L +T ADGV + +G T+ ++L+D + V Sbjct: 236 TKIIGVEPYGAASMTLSLHEGHRV-KLSNVDTFADGVAVALVGEYTFAKCQELIDGMVLV 294 Query: 263 TEDEIKYATQLVWERMKLLIEPTAGVGLAAVLSQHFQTVSPEVKNICIVLSGGNVDLTSL 322 D I A + V++ + ++E T+G A + + + + +NI + SG N+D + L Sbjct: 295 ANDGISAAIKDVYDEGRNILE-TSGAVAIAGAAAYCEFYKIKNENIVAIASGANMDFSKL 353 Query: 323 SWVKQ 327 V + Sbjct: 354 HKVTE 358 >1TDJ-A nrPDB Length = 514 Score = 122 bits (307), Expect = 2e-28, Method: Compositional matrix adjust. Identities = 96/310 (30%), Positives = 162/310 (52%), Gaps = 6/310 (1%) Query: 19 IQDSVHLTPVLTSSILNQIAGRNLFFKCELFQKTGSFKIRGALNAIRGLIPDTLEGKPKA 78 + ++ +TP+ L+ + K E Q SFK+RGA + GL T E K Sbjct: 25 VYEAAQVTPLQKMEKLSSRLDNVILVKREDRQPVHSFKLRGAYAMMAGL---TEEQKAHG 81 Query: 79 VVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPNCKKLAIQAYGASIVYSEPSDESRENV 138 V+T S+GNH Q + +++ G+ A IV+P + K A++ +G ++ + + + Sbjct: 82 VITASAGNHAQGVAFSSARLGVKALIVMPTATADIKVDAVRGFGGEVLLHGANFDEAKAK 141 Query: 139 AQRIIQETEGILVHPNQEPAVIAGQGTIALEVLNQVPLVDALVVPVGGGGMVAGIAITIK 198 A + Q+ V P P VIAGQGT+ALE+L Q +D + VPVGGGG+ AG+A+ IK Sbjct: 142 AIELSQQQGFTWVPPFDHPMVIAGQGTLALELLQQDAHLDRVFVPVGGGGLAAGVAVLIK 201 Query: 199 TLKPSVKVYAAEPSNADDCYQSKLKGELTPNLHPPETIADGVK-SSIGLNTWPIIRDLVD 257 L P +KV A E ++ C ++ L +L A+GV IG T+ + ++ +D Sbjct: 202 QLMPQIKVIAVEAEDS-ACLKAALDAGHPVDLPRVGLFAEGVAVKRIGDETFRLCQEYLD 260 Query: 258 DVFTVTEDEIKYATQLVWERMKLLIEPTAGVGLAAVLSQHFQTVSPEVKNICIVLSGGNV 317 D+ TV D I A + ++E ++ + EP+ + LA + ++ + + + +LSG NV Sbjct: 261 DIITVDSDAICAAMKDLFEDVRAVAEPSGALALAG-MKKYIALHNIRGERLAHILSGANV 319 Query: 318 DLTSLSWVKQ 327 + L +V + Sbjct: 320 NFHGLRYVSE 329 >1PWH-A nrPDB Length = 327 Score = 73.9 bits (180), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 97/334 (29%), Positives = 159/334 (47%), Gaps = 47/334 (14%) Query: 20 QDSVHL-TPVLTSSILNQIAGRNLFFKCELFQKTGSFKIRGALNAIRGLIPDTLEGKPKA 78 Q+S+H+ TP+ S L+++AG ++F K + Q +GSFKIRG I L + K Sbjct: 4 QESLHVKTPLRDSMALSKVAGTSVFLKMDSSQPSGSFKIRG----IGHLCKMKAKQGCKH 59 Query: 79 VVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPNCKKLAIQAYGASI-VYSEPSDESREN 137 V S+GN G A YAA+ G+PA IVVP T P ++ GA++ V E DE+ + Sbjct: 60 FVCSSAGNAGMATAYAARRLGLPATIVVPSTTPALTIERLKNEGATVEVVGEMLDEAIQ- 118 Query: 138 VAQRIIQETEG-ILVHPNQEPAVIAGQGTIALEV---LNQVPLVDALVVPVGGGGMVAGI 193 +A+ + + G + + P +P + G ++ E+ L+ P A+V+ VGGGG++ G+ Sbjct: 119 LAKALEKNNPGWVYISPFDDPLIWEGHTSLVKELKETLSAKP--GAIVLSVGGGGLLCGV 176 Query: 194 AITIKTLK-PSVKVYAAEPSNADDCYQSKLKGELT--PNLHPPETIADGVKSSIGLNT-- 248 ++ + V + A E A + + +G+L P + V ++G+NT Sbjct: 177 VQGLREVGWEDVPIIAMETFGAHSFHAAVKEGKLVTLPKI-------TSVAKALGVNTVG 229 Query: 249 ---------WPIIRDLVDDVFTVTEDEIKYATQLVWERMKLLIEPTAGVGLAAV------ 293 PI +++ D VT A + + K+L+EP G LAAV Sbjct: 230 AQTLKLFYEHPIFSEVISDQEAVT------AIEKFVDDEKILVEPACGAALAAVYSGVVC 283 Query: 294 -LSQHFQTVSPEVKNICIVLSGGNVDLTSLSWVK 326 L + +P + IV G N+ L L +K Sbjct: 284 RLQAEARLQTPLASLVVIVCGGSNISLAQLQALK 317 >5JJC-A nrPDB Length = 342 Score = 70.5 bits (171), Expect = 9e-13, Method: Compositional matrix adjust. Identities = 59/209 (28%), Positives = 97/209 (46%), Gaps = 12/209 (5%) Query: 18 NIQDSVHLTPVLTSSILNQIAGRNLFFKCELFQKTGSFKIRGALNAIRGLIPDTLEGKPK 77 ++ D++ TP++ S +++ G +++ K E S K R AL IR L Sbjct: 4 SVLDTIGNTPLIRLSKASELTGCDIYGKAEFLNPGQSVKDRAALYIIRDAEKRGLLRPGG 63 Query: 78 AVVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPNCKKLAIQAYGASIV------YSEPS 131 +V ++GN G LT AK G IV+P+TA KK A++ GA ++ Y P+ Sbjct: 64 VIVEGTAGNTGIGLTMVAKALGYRTAIVIPETASQEKKDALRLLGAELIEVPAAPYRNPN 123 Query: 132 DESR--ENVAQRIIQETEGILVHPNQEPAVIAGQG---TIALEVLNQVP-LVDALVVPVG 185 + R +A+++ + + NQ + Q T A E+ +D V VG Sbjct: 124 NAVRLSGRLAEQLAKTEPNGAIWANQFDNTVNRQAHIETTAQEIWRDTSDQIDGFVAAVG 183 Query: 186 GGGMVAGIAITIKTLKPSVKVYAAEPSNA 214 GG +AG AI +K ++K+ A+P A Sbjct: 184 SGGTLAGTAIGLKERNHNIKIALADPHGA 212 >1M54-A nrPDB Length = 363 Score = 67.4 bits (163), Expect = 9e-12, Method: Compositional matrix adjust. Identities = 76/275 (27%), Positives = 113/275 (41%), Gaps = 31/275 (11%) Query: 42 LFFKCELFQKTGSFKIRGALNAIRGLIPDTLEGKPKAVVTHSSGNHGQALTYAAKLEGIP 101 L KCE F GS K R +L I D ++ +SGN G L AA + G Sbjct: 62 LLAKCEFFNAGGSVKDRISLRMIEDAERDGTLKPGDTIIEPTSGNTGIGLALAAAVRGYR 121 Query: 102 AYIVVPQTAPNCKKLAIQAYGASIVYSE-----PSDESRENVAQRIIQE--TEGILVHPN 154 IV+P+ + K ++A GA IV + S ES VA R+ E IL Sbjct: 122 CIIVMPEKMSSEKVDVLRALGAEIVRTPTNARFDSPESHVGVAWRLKNEIPNSHILDQYR 181 Query: 155 QEPAVIAGQGTIALEVLNQVP-LVDALVVPVGGGGMVAGIAITIKTLKPSVKVYAAEPSN 213 +A T A E+L Q +D LV VG GG + GIA +K P ++ +P Sbjct: 182 NASNPLAHYDTTADEILQQCDGKLDMLVASVGTGGTITGIARKLKEKCPGCRIIGVDPEG 241 Query: 214 ADDCYQSKLKGELTPNLHPPETIADGVKSS-----IGLNTWPII--RDLVDDVFTVTEDE 266 + L PE + +++ IG + P + R +VD F ++E Sbjct: 242 S--------------ILAEPEELNQTEQTTYEVEGIGYDFIPTVLDRTVVDKWFKSNDEE 287 Query: 267 IKYATQLVWERMKLLIEPTAG--VGLAAVLSQHFQ 299 +++ + LL +AG V +A +Q Q Sbjct: 288 AFTFARMLIAQEGLLCGGSAGSTVAVAVKAAQELQ 322 >4COO-A nrPDB Length = 563 Score = 66.6 bits (161), Expect = 1e-11, Method: Compositional matrix adjust. Identities = 76/276 (27%), Positives = 113/276 (40%), Gaps = 31/276 (11%) Query: 41 NLFFKCELFQKTGSFKIRGALNAIRGLIPDTLEGKPKAVVTHSSGNHGQALTYAAKLEGI 100 L KCE F GS K R +L I D ++ +SGN G L AA + G Sbjct: 126 ELLAKCEFFNAGGSVKDRISLRMIEDAERDGTLKPGDTIIEPTSGNTGIGLALAAAVRGY 185 Query: 101 PAYIVVPQTAPNCKKLAIQAYGASIVYSE-----PSDESRENVAQRIIQE--TEGILVHP 153 IV+P+ + K ++A GA IV + S ES VA R+ E IL Sbjct: 186 RCIIVMPEKMSSEKVDVLRALGAEIVRTPTNARFDSPESHVGVAWRLKNEIPNSHILDQY 245 Query: 154 NQEPAVIAGQGTIALEVLNQVP-LVDALVVPVGGGGMVAGIAITIKTLKPSVKVYAAEPS 212 +A T A E+L Q +D LV VG GG + GIA +K P ++ +P Sbjct: 246 RNASNPLAHYDTTADEILQQCDGKLDMLVASVGTGGTITGIARKLKEKCPGCRIIGVDPE 305 Query: 213 NADDCYQSKLKGELTPNLHPPETIADGVKSS-----IGLNTWPII--RDLVDDVFTVTED 265 + L PE + +++ IG + P + R +VD F ++ Sbjct: 306 GS--------------ILAEPEELNQTEQTTYEVEGIGYDFIPTVLDRTVVDKWFKSNDE 351 Query: 266 EIKYATQLVWERMKLLIEPTAG--VGLAAVLSQHFQ 299 E +++ + LL +AG V +A +Q Q Sbjct: 352 EAFTFARMLIAQEGLLCGGSAGSTVAVAVKAAQELQ 387 >5MMS-A nrPDB Length = 408 Score = 66.6 bits (161), Expect = 1e-11, Method: Compositional matrix adjust. Identities = 76/275 (27%), Positives = 113/275 (41%), Gaps = 31/275 (11%) Query: 42 LFFKCELFQKTGSFKIRGALNAIRGLIPDTLEGKPKAVVTHSSGNHGQALTYAAKLEGIP 101 L KCE F GS K R +L I D ++ +SGN G L AA + G Sbjct: 105 LLAKCEFFNAGGSVKDRISLRMIEDAERDGTLKPGDTIIEPTSGNTGIGLALAAAVRGYR 164 Query: 102 AYIVVPQTAPNCKKLAIQAYGASIVYSE-----PSDESRENVAQRIIQE--TEGILVHPN 154 IV+P+ + K ++A GA IV + S ES VA R+ E IL Sbjct: 165 CIIVMPEKMSSEKVDVLRALGAEIVRTPTNARFDSPESHVGVAWRLKNEIPNSHILDQYR 224 Query: 155 QEPAVIAGQGTIALEVLNQVP-LVDALVVPVGGGGMVAGIAITIKTLKPSVKVYAAEPSN 213 +A T A E+L Q +D LV VG GG + GIA +K P ++ +P Sbjct: 225 NASNPLAHYDTTADEILQQCDGKLDMLVASVGTGGTITGIARKLKEKCPGCRIIGVDPEG 284 Query: 214 ADDCYQSKLKGELTPNLHPPETIADGVKSS-----IGLNTWPII--RDLVDDVFTVTEDE 266 + L PE + +++ IG + P + R +VD F ++E Sbjct: 285 S--------------ILAEPEELNQTEQTTYEVEGIGYDFIPTVLDRTVVDKWFKSNDEE 330 Query: 267 IKYATQLVWERMKLLIEPTAG--VGLAAVLSQHFQ 299 +++ + LL +AG V +A +Q Q Sbjct: 331 AFTFARMLIAQEGLLCGGSAGSTVAVAVKAAQELQ 365 >6NMX-A nrPDB Length = 354 Score = 62.4 bits (150), Expect = 3e-10, Method: Compositional matrix adjust. Identities = 83/304 (27%), Positives = 133/304 (43%), Gaps = 32/304 (10%) Query: 26 TPVLTSSILNQIAGRNLFFKCELFQKTGSFKIRGALNAIRGLIPDTLEGKPKAVVTHSSG 85 TP++ L++ G L K E TGSFK RG + A+ E ++ S+G Sbjct: 31 TPLIHLPKLSEQLGIELHVKTEGVNPTGSFKDRGMVMAV----AKAKEEGNDTIMCASTG 86 Query: 86 NHGQALTYAAKLEGIPAYIVVPQTAPNCKKLAIQA--YGASIVYSEPSDESRENVAQRII 143 N A A + +++P KLA QA YGA I+ + + + + + I Sbjct: 87 NTSAAAAAYAARANMKCIVIIPNGKIAFGKLA-QAVMYGAEIIAIDGNFDDALKIVRSIC 145 Query: 144 QETEGILVHPNQEPAVIAGQGTIALEVLNQVPLV-DALVVPVGGGGMVAGIAITIK---- 198 +++ LV+ + P + GQ T A EV Q+ D L +PVG G ++ K Sbjct: 146 EKSPIALVN-SVNPYRLEGQKTAAFEVCEQLGEAPDVLAIPVGNAGNISAYWKGFKEYHE 204 Query: 199 ---TLKPSVKVYAAEPSNADDCYQSKLKGELTPNLHPPETIADGVKSSIGL-NTWPIIRD 254 T P ++ + AE S A ++ E+ N PETIA ++ IG +W Sbjct: 205 KNGTSLPKMRGFEAEGSAA------IVRNEVIEN---PETIATAIR--IGNPASWDKAVK 253 Query: 255 LVDD----VFTVTEDEIKYATQLVWERMKLLIEPTAGVGLAAVLSQHFQTVSPEVKNICI 310 ++ + VT+DEI +A QL+ + EP + +A VL Q P+ + Sbjct: 254 AAEESNGKIDEVTDDEILHAYQLIAREEGVFAEPGSCASIAGVLKQVKSGEIPKGSKVVA 313 Query: 311 VLSG 314 VL+G Sbjct: 314 VLTG 317 >3PC3-A nrPDB Length = 527 Score = 59.3 bits (142), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 59/207 (28%), Positives = 94/207 (45%), Gaps = 16/207 (7%) Query: 18 NIQDSVHLTPVLTSSILNQIAGRN-----LFFKCELFQKTGSFKIRGALNAIRGLIPDTL 72 NI + + TP++ LN I + ++ KCE GS K R ++ L Sbjct: 53 NILEVIGCTPLVK---LNNIPASDGIECEMYAKCEFLNPGGSVKDRIGYRMVQDAEEQGL 109 Query: 73 EGKPKAVVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPNCKKLAIQAYGASIVY--SEP 130 ++ +SGN G L A ++G IV+P+ N K A++ GA I+ +E Sbjct: 110 LKPGYTIIEPTSGNTGIGLAMACAVKGYKCIIVMPEKMSNEKVSALRTLGAKIIRTPTEA 169 Query: 131 SDESREN---VAQRIIQETEGILVHPNQEPA--VIAGQGTIALEVLNQVP-LVDALVVPV 184 + +S E VAQ++ +ET +V A +A A E+L Q+ VD +VV Sbjct: 170 AYDSPEGLIYVAQQLQRETPNSIVLDQYRNAGNPLAHYDGTAAEILWQLDNKVDMIVVSA 229 Query: 185 GGGGMVAGIAITIKTLKPSVKVYAAEP 211 G G ++GI IK PS ++ +P Sbjct: 230 GTAGTISGIGRKIKEQVPSCQIVGVDP 256 >4H27-A nrPDB Length = 364 Score = 58.9 bits (141), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 91/318 (28%), Positives = 147/318 (46%), Gaps = 26/318 (8%) Query: 26 TPVLTSSILNQIAGRNLFFKCELFQKTGSFKIRGALNAIRGLIPDTLEGKPKAVVTHSSG 85 TP+ S L+++AG +++ K + Q +GSFKIRG I + V SSG Sbjct: 47 TPIRDSMALSKMAGTSVYLKMDSAQPSGSFKIRG----IGHFCKRWAKQGCAHFVCSSSG 102 Query: 86 NHGQALTYAAKLEGIPAYIVVPQTAPNCKKLAIQAYGASI-VYSEPSDESRENVAQRIIQ 144 N G A YAA+ G+PA IVVP T P ++ GA++ V E DE+ E +A+ + + Sbjct: 103 NAGMAAAYAARQLGVPATIVVPGTTPALTIERLKNEGATVKVVGELLDEAFE-LAKALAK 161 Query: 145 ETEG-ILVHPNQEPAVIAGQGTIALEV---LNQVPLVDALVVPVGGGGMVAGIAITIKTL 200 G + + P +P + G +I E+ L + P AL V GG + + Sbjct: 162 NNPGWVYIPPFDDPLIWEGHASIVKELKETLWEKPGAIALSVGGGGLLCGVVQGLQ-EVG 220 Query: 201 KPSVKVYAAEPSNADDCYQSKLKGELTPNLHPPETIAD--GVKSSIGLNTWPIIRDLVDD 258 V V A E A + + G+L +L ++A GVK ++G + ++ Sbjct: 221 WGDVPVIAMETFGAHSFHAATTAGKLV-SLPKITSVAKALGVK-TVGAQALKLFQE--HP 276 Query: 259 VFT--VTEDEIKYATQLVWERMKLLIEPTAGVGLAAVLSQHFQTV-------SPEVKNIC 309 +F+ +++ E A + + K+L+EP G LAAV S Q + +P + Sbjct: 277 IFSEVISDQEAVAAIEKFVDDEKILVEPACGAALAAVYSHVIQKLQLEGNLRTPLPSLVV 336 Query: 310 IVLSGGNVDLTSLSWVKQ 327 IV G N+ L L +K+ Sbjct: 337 IVCGGSNISLAQLRALKE 354 >3FCA-A nrPDB Length = 291 Score = 58.5 bits (140), Expect = 4e-09, Method: Compositional matrix adjust. Identities = 74/297 (24%), Positives = 134/297 (45%), Gaps = 38/297 (12%) Query: 26 TPVLT-SSILNQIAGRNLFFKCELFQKTGSFKIRGALNAI-----RGLIPDTLEGKPKAV 79 TP++ SI ++IA K E GS K R AL I RGL+ + + Sbjct: 9 TPIVRLDSIDSRIA-----LKLEKNNPGGSVKDRPALFMILDAEKRGLLKN-------GI 56 Query: 80 VTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPNCKKLAIQAYGASIVYSEPSDESRENVA 139 V +SGN G A+ G + +P+T ++ ++ GA +V + P + + Sbjct: 57 VEPTSGNMGIAIAMIGAKRGHRVILTMPETMSVERRKVLKMLGAELVLT-PGELGMKGAV 115 Query: 140 QR---IIQETEGILVHPNQEP-AVIAGQGTIALEVLNQVPL-VDALVVPVGGGGMVAGIA 194 ++ I +ET +++ + P V + Q T E+L Q+ +DA V VG GG ++G+ Sbjct: 116 EKALEISRETGAHMLNQFENPYNVYSHQFTTGPEILKQMDYQIDAFVAGVGTGGTISGVG 175 Query: 195 ITIKTL-KPSVKVYAAEPSNADDCYQSKLKGELTPNLHPPETIADGVKSSIGLNTWPIIR 253 +K VK+ A EP+ + + P H + I G I + R Sbjct: 176 RVLKGFFGNGVKIVAVEPAKSPVLSGGQ------PGKHAIQGIGAGFVPKI------LDR 223 Query: 254 DLVDDVFTVTEDEIKYATQLVWERMKLLIEPTAGVGLAAVLSQHFQTVSPEVKNICI 310 ++D+V TV ++E + + ++ LL+ ++G +AA L + Q + P+ + + + Sbjct: 224 SVIDEVITVEDEEAYEMARYLAKKEGLLVGISSGANVAAAL-KVAQKLGPDARVVTV 279 >2RKB-A nrPDB Length = 318 Score = 54.7 bits (130), Expect = 5e-08, Method: Compositional matrix adjust. Identities = 82/313 (26%), Positives = 140/313 (44%), Gaps = 27/313 (8%) Query: 20 QDSVHL-TPVLTSSILNQIAGRNLFFKCELFQKTGSFKIRGALNAIRGLIPDTLEGKPKA 78 Q+ H+ TP+L S L+Q+AG +F KCE Q +GSFKIRG I + + + Sbjct: 1 QEPFHVVTPLLESWALSQVAGMPVFLKCENVQPSGSFKIRG----IGHFCQEMAKKGCRH 56 Query: 79 VVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPNCKKLAIQAYGASIVYSEPSDESRENV 138 +V S GN G A YAA+ GIPA IV+P++ +Q GA + + + Sbjct: 57 LVCSSGGNAGIAAAYAARKLGIPATIVLPESTSLQVVQRLQGEGAEVQLTGKVWDEANLR 116 Query: 139 AQRIIQETEGILVHPNQEPAVIAGQGTIA--LEVLNQVPLVDALVVPVGGGGMVAGIAIT 196 AQ + + V P P + G ++ L+ + + P ++ GGG + +A Sbjct: 117 AQELAKRDGWENVPPFDHPLIWKGHASLVQELKAVLRTPPGALVLAVGGGGLLAGVVAGL 176 Query: 197 IKTLKPSVKVYAAEPSNADDCYQSKLKGELTPNLHPPETIAD--GVKSSIG-----LNTW 249 ++ V + A E A C+ + + L ++A G K+ + Sbjct: 177 LEVGWQHVPIIAMETHGA-HCFNAAITAGKLVTLPDITSVAKSLGAKTVAARALECMQVC 235 Query: 250 PIIRDLVDDVFTVTEDEIKYATQLVWERMKLLIEPTAGVGLAAVLS------QHFQTVSP 303 I ++V+D V+ A Q + + ++L+EP G LAA+ S Q + P Sbjct: 236 KIHSEVVEDTEAVS------AVQQLLDDERMLVEPACGAALAAIYSGLLRRLQAEGCLPP 289 Query: 304 EVKNICIVLSGGN 316 + ++ +++ GGN Sbjct: 290 SLTSVVVIVCGGN 302 >2D1F-A nrPDB Length = 360 Score = 54.3 bits (129), Expect = 7e-08, Method: Compositional matrix adjust. Identities = 53/170 (31%), Positives = 81/170 (47%), Gaps = 12/170 (7%) Query: 26 TPVLTSSILNQIAGRNLFFKCELFQKTGSFKIRGALNAIRGLIPDTLEGKPKAVVTHSSG 85 TP++ ++ L++ G + K E TGSFK RG A+ D L +AV+ S+G Sbjct: 39 TPLIAATNLSKQTGCTIHLKVEGLNPTGSFKDRGMTMAVT----DALAHGQRAVLCASTG 94 Query: 86 NHGQALTYAAKLEGIPAYIVVPQTAPNCKKLAIQA--YGASIVYSEPSDESRENVAQRII 143 N + A GI +++PQ KLA QA +GA I+ + + + +A+++ Sbjct: 95 NTSASAAAYAARAGITCAVLIPQGKIAMGKLA-QAVMHGAKIIQIDGNFDDCLELARKMA 153 Query: 144 QETEGILVHPNQEPAVIAGQGTIALE---VLNQVPLVDALVVPVGGGGMV 190 + I + + P I GQ T A E VL P V AL PVG G + Sbjct: 154 ADFPTISLVNSVNPVRIEGQKTAAFEIVDVLGTAPDVHAL--PVGNAGNI 201 >5D84-A nrPDB Length = 326 Score = 53.1 bits (126), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 59/208 (28%), Positives = 98/208 (47%), Gaps = 19/208 (9%) Query: 16 HLNIQDSVHLTPVLTSSILNQIAGRN-LFFKCELFQKTGSFKIRGALNAIRGLIPDTLEG 74 H ++ DSV TP++ L+Q+ ++ +F K E GS K R A I I L Sbjct: 9 HDSLLDSVGQTPMVQ---LHQLFPKHEVFAKLEYMNPGGSMKDRPAKYIIEHGIKHGLIT 65 Query: 75 KPKAVVTHSSGNHGQALTYAAKLEGIPAYIVV-PQTAPNCKKLAIQAYGASIVYSEPSDE 133 + ++ +SGN G AL AK++G+ VV P+ +P K+ I++YGA++ E D Sbjct: 66 ENTHLIESTSGNLGIALAMIAKIKGLKLTCVVDPKISPTNLKI-IKSYGANVEMVEEPDA 124 Query: 134 SRENVAQRI---------IQETEGILVHPNQ--EPAVIAGQGTIALEVLNQVPLVDALVV 182 + RI I + I + N+ + G GT +E + Q +D V Sbjct: 125 HGGYLMTRIAKVQELLATIDDAYWINQYANELNWQSHYHGAGTEIVETIKQP--IDYFVA 182 Query: 183 PVGGGGMVAGIAITIKTLKPSVKVYAAE 210 PV G + G++ IK + P+ ++ A + Sbjct: 183 PVSTTGSIMGMSRKIKEVHPNAQIVAVD 210 >5C3U-A nrPDB Length = 366 Score = 52.0 bits (123), Expect = 4e-07, Method: Compositional matrix adjust. Identities = 88/344 (25%), Positives = 155/344 (45%), Gaps = 42/344 (12%) Query: 9 FADVEKAHLNIQDSVHLTPVLTSSILNQIAGRNLFFKCELFQKTGSFKIRG----ALNAI 64 F D++ H+ TP+L + L + N+F K E Q +GS K+RG A+ Sbjct: 12 FDDLQSLHV-------ATPLLHAPNLTKELECNVFLKMENIQPSGSVKMRGIGAFCYQAV 64 Query: 65 RGLIPDTLEGKPKAVVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPNCKKLAIQAYGAS 124 + G V S N A++Y A+ G+ A IVVP+ +I+ G+ Sbjct: 65 QT------RGTNIQFVCGSGPNTVLAVSYCARQLGVEAIIVVPKATNERICQSIRTDGSH 118 Query: 125 IVYSEPSDESRENVAQRIIQETEGILVHPNQEPAVIAGQGTIALEV---LNQVPLVDALV 181 ++ + + E A+++++ GI V + + G TI E+ LN P A++ Sbjct: 119 LILYGENWTAAEVHARKLVRRN-GIYVPSSDHALIWQGHSTIVQELKTQLNDNPPA-AII 176 Query: 182 VPVGGGGMVAGIAITIKTLK-PSVKVYAAEPSNADDCYQSKLKGELT----PNLHPPETI 236 PVGGGG++ G+ + ++ V V A E ++ S + GEL N I Sbjct: 177 CPVGGGGLLNGVIMGLQEADWKDVPVIAVETHGSNAFQASVVAGELVIMEKNNTIATSLI 236 Query: 237 ADGVKSS---IGLNTWPIIRDLVDDVFTVTEDEIKYATQLVWERMKLLIEPTAGVGLAAV 293 + V S + LN P++ F V++ A +L E K+L+E +AG L+ Sbjct: 237 SKAVSSKSLELSLNH-PVVP------FAVSDAMAADAVRLFAEDFKMLVEASAGAALSLC 289 Query: 294 LSQHFQTVSPEV---KNICIVLSGG-NVDLTSLS-WVKQAERPA 332 + + + P + K++ ++++GG ++ L L + K+ PA Sbjct: 290 YTHLIRDILPSLSPAKDVVVLVTGGSDISLAHLDEYRKKYMHPA 333 >6C2H-A nrPDB Length = 375 Score = 51.6 bits (122), Expect = 5e-07, Method: Compositional matrix adjust. Identities = 74/297 (24%), Positives = 126/297 (42%), Gaps = 31/297 (10%) Query: 18 NIQDSVHLTPVLTSSILNQIAG--RNLFFKCELFQKTGSFKIRGALNAIR-GLIPDTLEG 74 N+ D V TP++ L + G ++ K EL+ GS K R A + + + Sbjct: 35 NVIDLVGNTPLIALKKLPKALGIKPQIYAKLELYNPGGSIKDRIAKSMVEEAEASGRIHP 94 Query: 75 KPKAVVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPNCKKLAIQAYGASIVYSE----- 129 ++ +SGN G L ++G I +P+ N K ++A GA I+ + Sbjct: 95 SRSTLIEPTSGNTGIGLALIGAIKGYRTIITLPEKMSNEKVSVLKALGAEIIRTPTAAAW 154 Query: 130 PSDESRENVAQRIIQETEGI--------LVHPNQEPAVIAGQGTIALEVLNQVPLVDALV 181 S ES VA+++ +E G +++P + LE LN + A+V Sbjct: 155 DSPESHIGVAKKLEKEIPGAVILDQYNNMMNPEAHYFGTGREIQRQLEDLNLFDNLRAVV 214 Query: 182 VPVGGGGMVAGIAITIKTLKPSVKVYAAEPSNADDCYQSKLKGELTPNLHPPETIADGVK 241 G GG ++GI+ +K +++ A+P + S L P I D Sbjct: 215 AGAGTGGTISGISKYLKEQNDKIQIVGADP------FGSILA---QPENLNKTDITDYKV 265 Query: 242 SSIGLNTWPII--RDLVDDVFTVTEDE--IKYATQLVWERMKLLIEPTAGVGLAAVL 294 IG + P + R L+ DV+ T+D+ KYA QL+ +L+ ++G AV+ Sbjct: 266 EGIGYDFVPQVLDRKLI-DVWYKTDDKPSFKYARQLI-SNEGVLVGGSSGSAFTAVV 320 >5OHX-A nrPDB Length = 504 Score = 50.8 bits (120), Expect = 8e-07, Method: Compositional matrix adjust. Identities = 76/285 (26%), Positives = 123/285 (43%), Gaps = 24/285 (8%) Query: 42 LFFKCELFQKTGSFKIRGALNAIRGLIPDTLEGKPKAVVTHSSGNHGQALTYAAKLEGIP 101 ++ KCE GS K R A I+ L ++ +SGN G L AA + G Sbjct: 64 IYAKCEFLNPGGSVKDRIAYRMIQDAEDKGLLKPGCTIIEPTSGNTGIGLAMAAAVRGYK 123 Query: 102 AYIVVPQTAPNCKKLAIQAYGASIVY-----SEPSDESRENVAQRIIQET-EGILVHPNQ 155 IV+P+ + K + A GA I+ S S E+ +VAQ++ +E I++ Sbjct: 124 CIIVMPEKMSDEKISTLYALGAKIIRTPTEASWHSPEAHISVAQKLQKEIPNSIILDQYT 183 Query: 156 EPAV-IAGQGTIALEVLNQVP-LVDALVVPVGGGGMVAGIAITIKTLKPSVKVYAAEPSN 213 P +A A+E+ Q +D LV G GG ++GI +K L P++K+ A +P Sbjct: 184 NPGNPLAHYDQTAIEIWKQCEGKIDYLVAGAGTGGTISGIGRKLKELSPNIKIIAVDP-- 241 Query: 214 ADDCYQSKLKGE-LTPNLHPPETIADGVKSSIGLNTWPII--RDLVDDVFTVTEDEIKYA 270 KG L P+ + IG + P + R+++D ++E A Sbjct: 242 ---------KGSILDPSSDSQNEVGFYEVEGIGYDFIPTVLDRNVIDKWIKTEDNESLNA 292 Query: 271 TQLVWERMKLLIEPTAGVGLAAVLSQHFQTVSPEVKNICIVLSGG 315 +++ + LL ++G L A L PE K + I+L G Sbjct: 293 ARMLIRQEGLLCGGSSGAALIAALKIAKDI--PEEKRMVIILPDG 335 >5YGR-A nrPDB Length = 404 Score = 50.4 bits (119), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 45/197 (22%), Positives = 89/197 (45%), Gaps = 17/197 (8%) Query: 75 KPKAVVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPNCKKLAIQAYGASIVYSEPSDES 134 K VT + GNHG+ + +AA+ G+ A + +P+ + + I+ +GA ++ + + Sbjct: 116 KDCVFVTATDGNHGRGVAWAAEQLGLKAVVYMPKGSSLIRAENIRHHGAECTITDLNYDD 175 Query: 135 RENVAQRIIQETEGILVHPNQEPA-------VIAGQGTIALEVLNQV-----PLVDALVV 182 +A R+ Q +L+ ++ G T+A+E Q+ PL L++ Sbjct: 176 AVRLAHRMAQTKGWVLLQDTAWTGYEEIPTWIMQGYMTLAVEAYEQLAETNSPLPTHLIL 235 Query: 183 PVGGGGMVAGI-AITIKTLKPSV-KVYAAEPSNADDCYQSKLKGELTPNLHPPE--TIAD 238 G G + ++ ++ ++ + EP A+ YQS + + P+ + TI Sbjct: 236 QAGVGSFAGSVMGYFVEKMQENIPNIIVVEPHQANCLYQSAVMDDGQPHCVTGDMATIMA 295 Query: 239 GVKSSI-GLNTWPIIRD 254 G+ + +WPIIRD Sbjct: 296 GLACGEPNIISWPIIRD 312 >2Q3D-A nrPDB Length = 313 Score = 49.7 bits (117), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 81/298 (27%), Positives = 133/298 (44%), Gaps = 39/298 (13%) Query: 15 AHLNIQDSVH----LTPVLTSSILNQIAGRNLFFKCELFQKTGSFKIRGALNAIR----- 65 +H++I + + TP++ + A ++ K E F S K R + ++ Sbjct: 2 SHMSIAEDITQLIGRTPLVRLRRVTDGAVADIVAKLEFFNPANSVKDRIGVAMLQAAEQA 61 Query: 66 GLI-PDTLEGKPKAVVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPNCKKLAIQAYGAS 124 GLI PDT+ ++ +SGN G AL G + +P+T +++ ++AYGA Sbjct: 62 GLIKPDTI------ILEPTSGNTGIALAMVCAARGYRCVLTMPETMSLERRMLLRAYGAE 115 Query: 125 IVYSEPSDESRENVAQ-RIIQETEGILVHPNQ-----EPAVIAGQGTIALEVLNQVP-LV 177 ++ + +D +A+ + +T+ P Q PA+ + T A EV V Sbjct: 116 LILTPGADGMSGAIAKAEELAKTDQRYFVPQQFENPANPAI--HRVTTAEEVWRDTDGKV 173 Query: 178 DALVVPVGGGGMVAGIAITIKTLKPSVKVYAAEPSNADDCYQSKLKGELTPNLHPPETIA 237 D +V VG GG + G+A IK KPS + A EP+ A KG HP + I Sbjct: 174 DIVVAGVGTGGTITGVAQVIKERKPSARFVAVEPA-ASPVLSGGQKGP-----HPIQGIG 227 Query: 238 DGVKSSIGLNTWPIIRDLVDDVFTV-TEDEIKYATQLVWERMKLLIEPTAGVGLAAVL 294 G + + +DLVD++ TV ED + A +L E LL+ ++G A L Sbjct: 228 AGFVPPV------LDQDLVDEIITVGNEDALNVARRLAREE-GLLVGISSGAATVAAL 278 >5I7O-A nrPDB Length = 326 Score = 48.5 bits (114), Expect = 4e-06, Method: Compositional matrix adjust. Identities = 56/211 (26%), Positives = 92/211 (43%), Gaps = 9/211 (4%) Query: 41 NLFFKCELFQKTGSFKIRGALNAIRGLIPDTLEGKPKAVVTHSSGNHGQALTYAAKLEGI 100 L+ K E TGS K R A+ I D L ++ +SGN G +L AA+L+G Sbjct: 39 RLWAKLEDRNPTGSIKDRPAVRMIEQAEADGLLRPGATILEPTSGNTGISLAMAARLKGY 98 Query: 101 PAYIVVPQTAPNCKKLAIQAYGASIVYSEPSDESRENVA---QRIIQETEGILVHPNQEP 157 V+P+ ++ ++ YGA I++S S VA + ++++ P Sbjct: 99 RLICVMPENTSVERRQLLELYGAQIIFSAAEGGSNTAVATAKELAATNPSWVMLYQYGNP 158 Query: 158 AVIAGQ--GTIALEVLNQVPLVDALVVPVGGGGMVAGIAITIKTLKPSVKVYAAEPSNAD 215 A GT E+L +P + V +G G + G ++ +VK+ AAEP + Sbjct: 159 ANTDSHYCGT-GPELLADLPEITHFVAGLGTTGTLMGTGRFLREHVANVKIVAAEPRYGE 217 Query: 216 DCYQSKLKGE-LTPNLHPPETIADGVKSSIG 245 Y + E P L+ PE + + S+G Sbjct: 218 GVYALRNMDEGFVPELYDPEILT--ARYSVG 246 >2PQM-A nrPDB Length = 343 Score = 47.4 bits (111), Expect = 9e-06, Method: Compositional matrix adjust. Identities = 65/244 (26%), Positives = 101/244 (41%), Gaps = 22/244 (9%) Query: 39 GRNLFFKCELFQKTGSFKIRGALNAIRGLIPDTLEGKPKAVVTHSSGNHGQALTYAAKLE 98 G + K E F S K R N + I D ++ +SGN G AL A + Sbjct: 41 GTRILVKLEYFNPMSSVKDRVGFNIVYQAIKDGRLKPGMEIIESTSGNTGIALCQAGAVF 100 Query: 99 GIPAYIVVPQTAPNCKKLAIQAYGASIVYSEPSDESRENVAQ--RIIQETEGILVHPNQ- 155 G I +P T +++ ++A+GA ++ +E + + ++I+E G NQ Sbjct: 101 GYRVNIAMPSTMSVERQMIMKAFGAELILTEGKKGMPGAIEEVNKMIKENPGKYFVANQF 160 Query: 156 -EPAVIAGQGTIALEVLNQVP-LVDALVVPVGGGGMVAGIAITIKTLKPSVKVYAAEPSN 213 P A A E+ VD +V VG G V G+A +K K +K+ A EP Sbjct: 161 GNPDNTAAHHYTANEIWEDTDGEVDIVVSAVGTSGTVIGVAEKLKEKKKGIKIIAVEPEE 220 Query: 214 ADDCYQSKLKGELTPNLHPPETIADGVKSSIGLNTWPII--RDLVDDVFTV-TEDEIKYA 270 + + K KG P I IG P I ++ VD++ + T+D K A Sbjct: 221 S-AVLEGKAKG--------PHGI-----QGIGAGFIPDIYKKEFVDEIIPIKTQDAWKMA 266 Query: 271 TQLV 274 +V Sbjct: 267 RAVV 270 >5B1I-A nrPDB Length = 311 Score = 47.0 bits (110), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 54/187 (28%), Positives = 85/187 (45%), Gaps = 21/187 (11%) Query: 41 NLFFKCELFQKTGSFKIR-GALNAIRGLIPDTLE-GKPKA---VVTHSSGNHGQALTYAA 95 +++ K E+F GS R GA LI D L+ G+ A ++ ++GN G L A Sbjct: 27 HIYAKLEMFNPGGSIADRLGAY-----LIEDGLQRGRVNAKTTIIEPTAGNTGIGLALAT 81 Query: 96 KLEGIPAYIVVPQTAPNCKKLAIQAYGASIVYSEPSDE-------SRENVAQRIIQETEG 148 + + +VVP+ K++ +QA GA IV++ PS+E E +A I Sbjct: 82 QAHHLRTILVVPEKFSMEKQVLMQALGAEIVHT-PSEEGIKGAIRKAEALAATISNSYVP 140 Query: 149 ILVHPNQEPAVIAGQGTIALEVLNQVPL-VDALVVPVGGGGMVAGIAITIKTLKPSVKVY 207 + PA A T+A E+L +P + A V G GG AG+A ++ + K Sbjct: 141 MQFKNPANPA--AYYHTLAPEILADMPAPITAFVAGAGSGGTFAGVAAYLQAQDSATKAV 198 Query: 208 AAEPSNA 214 EP + Sbjct: 199 VVEPEGS 205 >2ZSJ-A nrPDB Length = 352 Score = 46.6 bits (109), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 75/288 (26%), Positives = 127/288 (44%), Gaps = 37/288 (12%) Query: 26 TPVLTSSILNQIAG--RNLFFKCELFQKTGSFKIRGALNAIRGLIPDTLEGKPKAVVTHS 83 TP++ + L + G ++ K E TGSFK RG AI +E +AV+ S Sbjct: 31 TPLIEADNLARAIGFKGKIYLKYEGLNPTGSFKDRGMTLAIS----KAVEAGKRAVICAS 86 Query: 84 SGNHGQALTYAAKLEGIPAYIVVPQTAPNCKKLA-IQAYGASIVYSEPSDESRENVAQRI 142 +GN + A G+ AY+++P+ A KL+ YGA ++ + + + N+ ++ Sbjct: 87 TGNTSASAAAYAARAGLRAYVLLPKGAVAIGKLSQAMIYGAKVLAIQGTFDDALNIVRK- 145 Query: 143 IQETEGILVHPNQEPAVIAGQGTIALEV---LNQVPLVDALVVPVGGGGMVA----GIAI 195 I E + + + P I GQ T A E+ L + P D +PVG G + G I Sbjct: 146 IGENFPVEIVNSVNPYRIEGQKTAAFEICDTLGEAP--DYHFIPVGNAGNITAYWKGFKI 203 Query: 196 TIKTLK----PSVKVYAAEPSNADDCYQSKLKGELTPNLHPPETIADGVKSSIGL-NTW- 249 + K P + + AE + +KG N P+TIA +K IG +W Sbjct: 204 YYEEGKITKLPRMMGWQAEGA------APIVKGYPIKN---PQTIATAIK--IGNPYSWK 252 Query: 250 ---PIIRDLVDDVFTVTEDEIKYATQLVWERMKLLIEPTAGVGLAAVL 294 ++ + V++ EI YA +L+ + EP + +A ++ Sbjct: 253 SALKAAQESGGKIDAVSDSEILYAYKLIASTEGVFCEPASAASVAGLI 300 >2BHS-A nrPDB Length = 303 Score = 46.2 bits (108), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 51/203 (25%), Positives = 86/203 (42%), Gaps = 16/203 (7%) Query: 19 IQDSVHLTPVLTSSILNQIAGRNLFFKCELFQKTGSFKIRGALNAI-----RGLIPDTLE 73 ++ ++ TP++ + G ++ K E GS K R AL+ I RG I Sbjct: 4 LEQTIGNTPLVKLQRMGPDNGSEVWLKLEGNNPAGSVKDRAALSMIVEAEKRGEI----- 58 Query: 74 GKPKAV-VTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPNCKKLAIQAYGAS--IVYSEP 130 KP V + +SGN G AL A L+G +++P ++ A++AYGA +V E Sbjct: 59 -KPGDVLIEATSGNTGIALAMIAALKGYRMKLLMPDNMSQERRAAMRAYGAELILVTKEQ 117 Query: 131 SDESRENVAQRIIQETEGILVHPNQEPAV-IAGQGTIALEVLNQV-PLVDALVVPVGGGG 188 E ++A + EG L+ P A T E+ Q + V +G G Sbjct: 118 GMEGARDLALEMANRGEGKLLDQFNNPDNPYAHYTTTGPEIWQQTGGRITHFVSSMGTTG 177 Query: 189 MVAGIAITIKTLKPSVKVYAAEP 211 + G++ ++ V + +P Sbjct: 178 TITGVSRFMREQSKPVTIVGLQP 200 >2JC3-A nrPDB Length = 303 Score = 45.8 bits (107), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 51/203 (25%), Positives = 88/203 (43%), Gaps = 16/203 (7%) Query: 19 IQDSVHLTPVLTSSILNQIAGRNLFFKCELFQKTGSFKIRGALNAI-----RGLIPDTLE 73 ++ ++ TP++ + G ++ K E GS K R AL+ I RG I Sbjct: 4 LEQTIGNTPLVKLQRIGPDNGSEIWVKLEGNNPAGSVKDRAALSMIVEAEKRGEI----- 58 Query: 74 GKPKAV-VTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPNCKKLAIQAYGAS--IVYSEP 130 KP V + +SGN G AL A L+G +++P ++ A++AYGA +V E Sbjct: 59 -KPGDVLIEATSGNTGIALAMIAALKGYRMKLLMPDNMSQERRAAMRAYGAELILVTKEQ 117 Query: 131 SDESRENVAQRIIQETEGILVHPNQEPAV-IAGQGTIALEVLNQVP-LVDALVVPVGGGG 188 E ++A + + EG L+ P A T E+ Q + V +G G Sbjct: 118 GMEGARDLALAMSERGEGKLLDQFNNPDNPYAHYTTTGPEIWRQTSGRITHFVSSMGTTG 177 Query: 189 MVAGIAITIKTLKPSVKVYAAEP 211 + G++ ++ + V + +P Sbjct: 178 TITGVSRFLREQEKPVTIVGLQP 200 >1UIN-A nrPDB Length = 351 Score = 45.8 bits (107), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 49/156 (31%), Positives = 74/156 (47%), Gaps = 11/156 (7%) Query: 39 GRNLFFKCELFQKTGSFKIRGALNAIRGLIPDTLEGKPKAVVTHSSGNHGQALTYAAKLE 98 G L+ K E TGSFK RG A+ +EG +AV S+GN + A Sbjct: 44 GIRLYAKYEGLNPTGSFKDRGMTLAVS----KAVEGGAQAVACASTGNTAASAAAYAARA 99 Query: 99 GIPAYIVVPQTAPNCKKLAIQ-AYGASIVYSEPSDESRENVAQRIIQETEGILVHPNQEP 157 GI A +V+P K+A +GA IV E + + + Q++ + LV+ + P Sbjct: 100 GILAIVVLPAGYVALGKVAQSLVHGARIVQVEGNFDDALRLTQKLTEAFPVALVN-SVNP 158 Query: 158 AVIAGQGTIALEVLNQV---PLVDALVVPVGGGGMV 190 + GQ T+A EV++++ P AL PVG G + Sbjct: 159 HRLEGQKTLAFEVVDELGDAPHYHAL--PVGNAGNI 192 >4I1Y-A nrPDB Length = 314 Score = 45.1 bits (105), Expect = 5e-05, Method: Compositional matrix adjust. Identities = 79/275 (28%), Positives = 120/275 (43%), Gaps = 38/275 (13%) Query: 18 NIQDSVHLTPVLTSSILNQIAGRNLFFKCELFQKTGSFKIRGALNAIR-----GLI-PDT 71 NI + TP++ + A ++ K E F GS K R + I GLI PDT Sbjct: 10 NIAQLIGGTPLVRLRRVTDGAAADVVAKLESFNPAGSIKDRIGVAMIDAAEKAGLIKPDT 69 Query: 72 LEGKPKAVVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPNCKKLAIQAYGASIVYSEPS 131 + ++ +SGN G AL + G + +P T +++ ++AYGA +V + + Sbjct: 70 I------ILEPTSGNTGIALAMVSAARGYKCVLTMPDTMSIERRMLLRAYGAELVLTPGA 123 Query: 132 DESRENVAQ-RIIQETEGILVHPNQ-----EPAVIAGQGTIALEVLNQVP-LVDALVVPV 184 + +A+ + +T+ P Q PAV A T A EV VD V V Sbjct: 124 EGMAGAIAKAEELAKTDDRYFIPQQFENPANPAVHA--VTTAEEVWRDTDGKVDIFVSGV 181 Query: 185 GGGGMVAGIAITIKTLKPSVKVYAAEPSNADDCYQSKLKGELTPNLHPPETIADGVKSSI 244 G GG + G+A IK +PS + A EP+ A KG HP + I Sbjct: 182 GTGGTITGVAQVIKQRRPSAQFVAVEPA-ASPVLSGGQKGP-----HPIQ--------GI 227 Query: 245 GLNTWPIIRD--LVDDVFTV-TEDEIKYATQLVWE 276 G P + D LVD+V TV +D ++ A ++ E Sbjct: 228 GAGFVPPVLDLALVDEVITVGNDDALELARRMATE 262 >2EFY-A nrPDB Length = 304 Score = 45.1 bits (105), Expect = 5e-05, Method: Compositional matrix adjust. Identities = 79/310 (25%), Positives = 130/310 (41%), Gaps = 29/310 (9%) Query: 17 LNIQDSVHLTPVLTSSILNQIAGRNLFFKCELFQKTGSFKIRGALNAI-----RGLIPDT 71 + ++ ++ TPV+ + + + ++ K E GS K R A I RG++ Sbjct: 1 MRVEGAIGKTPVVRLAKVVEPDMAEVWVKLEGLNPGGSIKDRPAWYMIKDAEERGIL--- 57 Query: 72 LEGKPKAVVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPNCKKLAIQAYGASIVYSEPS 131 G + +V +SGN G L A G + +P +K ++A+GA +V ++P Sbjct: 58 RPGSGQVIVEPTSGNTGIGLAMIAASRGYRLILTMPAQMSEERKRVLKAFGAELVLTDPE 117 Query: 132 DE---SRENVAQRIIQETEGILVHPNQEPA-VIAGQGTIALEVLNQVP-LVDALVVPVGG 186 +RE A R+ +E + + PA V A T E+ + +DA V G Sbjct: 118 RRMLAAREE-ALRLKEELGAFMPDQFKNPANVRAHYETTGPELYEALEGRIDAFVYGSGT 176 Query: 187 GGMVAGIAITIKTLKPSVKVYAAEPSNADDCYQSKLKGELTPNLHPPETIADGVKSSIGL 246 GG + G+ +K P VKV A EP+ ++ K+ G+ P I + + S Sbjct: 177 GGTITGVGRYLKERIPHVKVIAVEPARSNVLSGGKM-GQHGFQGMGPGFIPENLDLS--- 232 Query: 247 NTWPIIRDLVDDVFTV-TEDEIKYATQLVWERMKLLIEPTAGVGLAAVLSQHFQTVSPEV 305 L+D V V ED A +L E L + G+ AA+ Q + + P Sbjct: 233 --------LLDGVIQVWEEDAFPLARRLAREEGLFLGMSSGGIVWAAL--QVARELGPGK 282 Query: 306 KNICIVLSGG 315 + CI GG Sbjct: 283 RVACISPDGG 292 >4OFX-A nrPDB Length = 319 Score = 43.5 bits (101), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 57/207 (27%), Positives = 98/207 (47%), Gaps = 18/207 (8%) Query: 18 NIQDSVHLTPVLTSSILNQIAGRNLFFKCELFQKTGSFKIRGALNAIRGLIPDTLEGKPK 77 NI + TPV+ + Q L+ KCE GS K R I +GK K Sbjct: 8 NILQVIGKTPVVRLHRIGQSLPCELYGKCEFLNPGGSVKDRIGAAMIESA---EKQGKIK 64 Query: 78 ---AVVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPNCKKLAIQAYGASIVYSEPSD-- 132 ++ +SGN G + A ++G I +P+ + K++ ++A GA+I Y P++ Sbjct: 65 PGDTLIEPTSGNTGIGIALAGAVKGYRVIITMPEKMSHEKQVVLEALGATI-YRTPTEAA 123 Query: 133 ----ESRENVAQRIIQETEGILV---HPNQEPAVIAGQGTIALEVLNQV-PLVDALVVPV 184 ES ++A+R+ QE + + N E I Q T E+L+ + + +V+ V Sbjct: 124 YDDPESHISLAKRLNQEIPNSYILDQYSNAENPDIHYQ-TTGQEILDDMGENLSMVVMGV 182 Query: 185 GGGGMVAGIAITIKTLKPSVKVYAAEP 211 G GG + G+A +K + PS+++ +P Sbjct: 183 GTGGTIIGVAKKLKEVNPSIQIIGVDP 209 >4LMA-A nrPDB Length = 326 Score = 42.7 bits (99), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 93/331 (28%), Positives = 150/331 (45%), Gaps = 35/331 (10%) Query: 15 AHLNIQDSVHLTPVLTSSILNQIAG--RNLFFKCELFQKTGSFKIRGALNAIR-----GL 67 AH ++ + V TP++ + + Q G + K E S K R + I GL Sbjct: 11 AH-DVTELVGRTPLVQLNRIPQAEGCLGRIVMKLEGMNPAASVKDRIGTHMINSAEKAGL 69 Query: 68 I-PDTLEGKPKAVVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPNCKKLAIQAYGASIV 126 I P+T +V +SGN G AL A +G + +P+T ++ ++AYGA++ Sbjct: 70 INPET-----TVLVEPTSGNTGIALAMTAAAKGYRLILTMPETMSLERRAMLKAYGATLE 124 Query: 127 YSEPSDESRENV--AQRIIQETEG-ILVHPNQEPAVIA-GQGTIALEVLNQVP-LVDALV 181 + S + + AQ+I+ G ++ + P+ + T A E+ VD +V Sbjct: 125 LTPGSQGMKGAILRAQQIVDSIPGAYMLQQFRNPSNPEIHRLTTAEEIWQDTEGQVDFIV 184 Query: 182 VPVGGGGMVAGIAITIKTLKPSVKVYAAEPSNADDCYQSKLKGELTPNLHPPETIADGVK 241 VG GG + G+A IK+ KPS +V A EP N S + P H + I G Sbjct: 185 AGVGTGGTITGVAEVIKSRKPSFQVVAVEPFN------SPVISGGNPGPHKIQGIGAGFI 238 Query: 242 SSIGLNTWPIIRDLVDDVFTVTEDE-IKYATQLVWERMKLLIEPTAGVGLAAVLSQHFQT 300 + L T DL+D+V TV+++E ++ +L E LL ++G L A + Q Q Sbjct: 239 PEV-LRT-----DLIDEVITVSDEEAFQFGRRLAKEE-GLLSGISSGANLCAAI-QLAQR 290 Query: 301 VSPEVKNICIVL-SGGNVDLTSLSWVKQAER 330 E K I ++ S G L++L + ER Sbjct: 291 PENEGKLIVVIQPSFGERYLSTLMFQNIEER 321 >5B55-A nrPDB Length = 340 Score = 42.4 bits (98), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 30/108 (27%), Positives = 49/108 (45%) Query: 19 IQDSVHLTPVLTSSILNQIAGRNLFFKCELFQKTGSFKIRGALNAIRGLIPDTLEGKPKA 78 +++ V TP+L + R +F K E + TGS K R A ++ K Sbjct: 13 LENLVGKTPMLELIFDYKGEERRIFVKNESYNLTGSIKDRMAFYTLKKAYEKNEIKKGAP 72 Query: 79 VVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPNCKKLAIQAYGASIV 126 +V +SGN G A + + G P I +P +K I+++GA I+ Sbjct: 73 IVEATSGNTGIAFSAMGAILGHPVIIYMPDWMSEERKSLIRSFGAKII 120 >6AHI-A nrPDB Length = 314 Score = 40.4 bits (93), Expect = 0.001, Method: Compositional matrix adjust. Identities = 70/291 (24%), Positives = 120/291 (41%), Gaps = 32/291 (10%) Query: 19 IQDSVHLTPVLTSSILNQIAGRN--LFFKCELFQKTGSFKIR-GALNAIRGLIPDTLEGK 75 +QD++ TPV + + N ++ K E GS K R G G + K Sbjct: 7 MQDAIGRTPVFKFTNKDYPIPLNSAIYAKLEHLNPGGSVKDRLGQYLIGEGFKTGKITSK 66 Query: 76 PKAVVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPNCKKLAIQAYGASIVYSEPSDESR 135 ++ ++GN G AL A + VVP+ K+ ++A GA +V + P+ E Sbjct: 67 -TTIIEPTAGNTGIALALVAIKHHLKTIFVVPEKFSTEKQQIMRALGA-LVINTPTSEGI 124 Query: 136 ENVAQRIIQETEGI--------LVHPNQEPAVIAGQGTIALEVLNQVPL-VDALVVPVGG 186 ++ + E I +P+ A T+A E++ ++ + + V +G Sbjct: 125 SGAIKKSKELAESIPDSYLPLQFENPDNPAAYYH---TLAPEIVQELGTNLTSFVAGIGS 181 Query: 187 GGMVAGIAITIKTLKPSVKVYAAEPSNADDCYQSKLKGELTPNLHPPETIADGVKSSIGL 246 GG AG A +K P++++ EP S L G P H E I GV+ Sbjct: 182 GGTFAGTARYLKERIPAIRLIGVEPEG------SILNGG-EPGPHEIEGI--GVEF---- 228 Query: 247 NTWPIIRDLVDDVFTVTEDEIKYA-TQLVWERMKLLIEPTAGVGLAAVLSQ 296 P +L D F DE ++ T+ + ++ LL+ ++G A L + Sbjct: 229 -IPPFFENLDIDGFETISDEEGFSYTRKLAKKNGLLVGSSSGAAFVAALKE 278 >4D9G-A nrPDB Length = 398 Score = 40.0 bits (92), Expect = 0.002, Method: Compositional matrix adjust. Identities = 41/169 (24%), Positives = 76/169 (44%), Gaps = 19/169 (11%) Query: 74 GKPKAVVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPNCKKLAIQAYGASIV-----YS 128 G+ T + GNHG+ + +AA+ G A I +P+ + + AI GA + Y Sbjct: 110 GEKMTFATTTDGNHGRGVAWAAQQLGQNAVIYMPKGSAQERVDAILNLGAECIVTDMNYD 169 Query: 129 EPSDESRENVAQR---IIQET--EGILVHPNQEPAVIAGQGTIALEVLNQVPLVDA---- 179 + + ++ Q ++Q+T EG P ++ G T+A E + Q+ + Sbjct: 170 DTVRLTMQHAQQHGWEVVQDTAWEGYTKIPTW---IMQGYATLADEAVEQMREMGVTPTH 226 Query: 180 LVVPVGGGGMVAGI-AITIKTLKP-SVKVYAAEPSNADDCYQSKLKGEL 226 +++ G G M G+ + P ++ EP AD Y+S +KG++ Sbjct: 227 VLLQAGVGAMAGGVLGYLVDVYSPQNLHSIIVEPDKADCIYRSGVKGDI 275 >5J5V-A nrPDB Length = 323 Score = 39.7 bits (91), Expect = 0.002, Method: Compositional matrix adjust. Identities = 77/299 (25%), Positives = 127/299 (42%), Gaps = 39/299 (13%) Query: 34 LNQIAGRNLFFKCELFQKTGSFKIRGALNAI-----RGLIPDTLEGKPKAVVTHSSGNHG 88 LN+I + K E + S K R N I RG++ +E +V +SGN G Sbjct: 20 LNRIGNGRILAKVESRNPSFSVKCRIGANMIWDAEKRGVLKPGVE-----LVEPTSGNTG 74 Query: 89 QALTYAAKLEGIPAYIVVPQTAPNCKKLAIQAYGASIVYSEPSDESRENVAQRIIQETEG 148 AL Y A G + +P+T ++ ++A GA++V +E + + IQ+ E Sbjct: 75 IALAYVAAARGYKLTLTMPETMSIERRKLLKALGANLVLTEGAKGMK-----GAIQKAEE 129 Query: 149 ILVHPNQEPAVIAGQ-----------GTIALEVLNQVP-LVDALVVPVGGGGMVAGIAIT 196 I V N E ++ Q T E+ VD + VG GG + G++ Sbjct: 130 I-VASNPEKYLLLQQFSNPANPEIHEKTTGPEIWEDTDGQVDVFIAGVGTGGTLTGVSRY 188 Query: 197 IKTLKPSVKV--YAAEPSNADDCYQSKLKGELTPNLHPPETIADG-VKSSIGLNTWPIIR 253 IK K + A EP+++ Q+ E+ P H + I G + +++ L Sbjct: 189 IKGTKGKTDLISVAVEPTDSPVIAQALAGEEIKPGPHKIQGIGAGFIPANLDLK------ 242 Query: 254 DLVDDVFTVTEDEIKYATQLVWERMKLLIEPTAGVGLAAVLSQHFQTVSPEVKNICIVL 312 LVD V +T +E + + E +L ++G +AA L + S KNI ++L Sbjct: 243 -LVDKVIGITNEEAISTARRLMEEEGILAGISSGAAVAAALKLQ-EDESFTNKNIVVIL 299 >5XW3-A nrPDB Length = 315 Score = 39.3 bits (90), Expect = 0.002, Method: Compositional matrix adjust. Identities = 55/221 (24%), Positives = 92/221 (41%), Gaps = 37/221 (16%) Query: 17 LNIQDSVH----LTPVLTSSILNQIAGRNLFFKCELFQKTGSFKIRGALNAIRGLIPDTL 72 +N+ VH TP++ + + G LF K E + GS K R R LI D L Sbjct: 1 MNVYRGVHELIGHTPIVEITRFSLPEGVRLFAKLEFYNPGGSVKDRLG----RELIEDAL 56 Query: 73 EGKPKAVVTH-------SSGNHGQALTYAAKLEGIPAYIVVPQTAPNCKKLAIQAYGASI 125 E K +VT ++GN G L AA + + VP+ K+ ++A GA++ Sbjct: 57 E---KGLVTEGGTIIEPTAGNTGIGLALAALQHDLRVIVCVPEKFSIEKQELMKALGATV 113 Query: 126 VYSEPSDESRENV---AQRIIQETEGILVHPNQ-EPAVIAGQG-------TIALEVLNQV 174 V++ P+++ A+ ++ E PN P+ A + T+ E+ + + Sbjct: 114 VHT-PTEQGMTGAIAKAKELVNEI------PNSYSPSQFANEANPRAYFKTLGPELWSAL 166 Query: 175 -PLVDALVVPVGGGGMVAGIAITIKTLKPSVKVYAAEPSNA 214 ++ V G GG G A +K +K EP + Sbjct: 167 NGEINIFVAGAGTGGTFMGTASYLKEKNIDIKTVIVEPEGS 207 >2EGU-A nrPDB Length = 308 Score = 38.9 bits (89), Expect = 0.003, Method: Compositional matrix adjust. Identities = 51/181 (28%), Positives = 82/181 (45%), Gaps = 10/181 (5%) Query: 41 NLFFKCELFQKTGSFKIRGALNAIRGLIPDTLEGKPK---AVVTHSSGNHGQALTYAAKL 97 +++ K E S K R AL I GK K +V +SGN G L A Sbjct: 30 DVYLKLEFMNPGSSVKDRIALAMIEAA---EKAGKLKPGDTIVEPTSGNTGIGLAMVAAA 86 Query: 98 EGIPAYIVVPQTAPNCKKLAIQAYGASIVYSEPSDESRENVAQRIIQETEGILVHPNQ-- 155 +G A +V+P T ++ ++AYGA +V + + R +A+ E P Q Sbjct: 87 KGYKAVLVMPDTMSLERRNLLRAYGAELVLTPGAQGMRGAIAKAEELVREHGYFMPQQFK 146 Query: 156 -EPAVIAGQGTIALEVLNQV-PLVDALVVPVGGGGMVAGIAITIKTLKPSVKVYAAEPSN 213 E + T E++ Q+ +DA V VG GG + G ++ P++K+YA EP++ Sbjct: 147 NEANPEIHRLTTGKEIVEQMGDQLDAFVAGVGTGGTITGAGKVLREAYPNIKIYAVEPAD 206 Query: 214 A 214 + Sbjct: 207 S 207 >3VBE-A nrPDB Length = 344 Score = 38.5 bits (88), Expect = 0.004, Method: Compositional matrix adjust. Identities = 50/203 (24%), Positives = 93/203 (45%), Gaps = 20/203 (9%) Query: 26 TPVLTSSILNQIAGRNLFFKCELFQKTGSFKIRGALNAIRGLIPDTLE------GKPKAV 79 TP++ + + + G + K E+ Q T S K R A +I D E GK + Sbjct: 36 TPLVYLNKVTEGCGAYVAVKQEMMQPTASIKDRPAY----AMITDAEEKNLITPGK-TTL 90 Query: 80 VTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPNCKKLAIQAYGASIVYSEPSDESRENV- 138 + +SGN G ++ + A ++G + +P +++ ++A+GA ++ ++P+ V Sbjct: 91 IEPTSGNMGISMAFMAAMKGYKMVLTMPSYTSLERRVTMRAFGAELILTDPAKGMGGTVK 150 Query: 139 -AQRIIQETEGI-----LVHPNQEPAVIAGQGTIALEVLNQVPLVDALVVPVGGGGMVAG 192 A +++ T +P G E N VD V+ +G GG V+G Sbjct: 151 KAYELLENTPNAHMLQQFSNPANTQVHFETTGPEIWEDTNG--QVDIFVMGIGSGGTVSG 208 Query: 193 IAITIKTLKPSVKVYAAEPSNAD 215 + +K+ P+VK+Y EPS ++ Sbjct: 209 VGQYLKSKNPNVKIYGVEPSESN 231 >2ISQ-A nrPDB Length = 320 Score = 37.0 bits (84), Expect = 0.011, Method: Compositional matrix adjust. Identities = 63/252 (25%), Positives = 104/252 (41%), Gaps = 51/252 (20%) Query: 45 KCELFQKTGSFKIRGALNAI-----RGLIPDTLEGKP--KAVVTHSSGNHGQALTYAAKL 97 K E+ + S K R + I +GLI KP ++ +SGN G L + A Sbjct: 33 KLEMMEPCSSVKDRIGFSMISDAEKKGLI------KPGESVLIEPTSGNTGVGLAFTAAA 86 Query: 98 EGIPAYIVVPQTAPNCKKLAIQAYGASIVYSEPSDESRENV--AQRIIQET-EGILVHPN 154 +G I +P + +++ + A+G +V ++P+ + + A+ I+ +T G ++ Sbjct: 87 KGYKLIITMPASMSTERRIILLAFGVELVLTDPAKGMKGAIAKAEEILAKTPNGYMLQQF 146 Query: 155 QEPA------------VIAGQGTIALEVLNQVPLVDALVVPVGGGGMVAGIAITIKTLKP 202 + PA + G G +D V +G GG + G +K Sbjct: 147 ENPANPKIHYETTGPEIWKGTGG----------KIDGFVSGIGTGGTITGAGKYLKEQNA 196 Query: 203 SVKVYAAEPSNADDCYQSKLKGELTPNLHPPETIADGVKSSIGLNTWPIIRDLVDDVFTV 262 +VK+Y EP + K P H + I G S+ LN DL+D+V V Sbjct: 197 NVKLYGVEPVESAILSGGK------PGPHKIQGIGAGFIPSV-LNV-----DLIDEVVQV 244 Query: 263 TEDE-IKYATQL 273 + DE I A QL Sbjct: 245 SSDESIDMARQL 256 >3X43-A nrPDB Length = 332 Score = 36.2 bits (82), Expect = 0.018, Method: Compositional matrix adjust. Identities = 69/285 (24%), Positives = 120/285 (42%), Gaps = 22/285 (7%) Query: 18 NIQDSVHLTPVLTSSILNQIAGRN--LFFKCELFQKTGSFKIRGALNAIRGLIPDTLEGK 75 +I D++ TP++ L ++A + ++ K E F GS K R AL+ + L Sbjct: 6 SILDTIGRTPIVR---LQRMAPEHTSVYVKVESFNPGGSVKDRLALSVVLDAEAKGLLKP 62 Query: 76 PKAVVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPNCKKLAIQAYGASIVYSEPSDESR 135 +V +SGN G AL A G V+ T ++ I+AYG +V S+ Sbjct: 63 GDTIVECTSGNVGIALAMVAAARGYRFVAVMGDTYSVERRKLIRAYGGKLVLFPGHLGSK 122 Query: 136 EN--VAQRIIQETEGILVHPNQEPAVIA-GQGTIALEVLNQVP--LVDALVVPVGGGGMV 190 +A + ++ PA + + T A E+L +D V G G + Sbjct: 123 GGNLIADELAEKYGWFRARQFDNPANPSYHRETTASEILADFAGKRLDHFVTGFGTTGTL 182 Query: 191 AGIAITIKTLKPSVKVYAAEPSNADDCYQSKLKGELTPNLHPPETIADGVKSSIGLNTWP 250 G+ ++ +P V+V A EPSNA +GE +P H + +A + Sbjct: 183 TGVGQMLRVARPEVRVVALEPSNA----AMLARGEWSP--HQIQGLAPNFVPGV------ 230 Query: 251 IIRDLVDDVFTVTEDEIKYATQLVWERMKLLIEPTAGVGLAAVLS 295 + R ++DD+ T+ E + ++ + + +AG +A LS Sbjct: 231 LDRSVIDDLVTMDEVTARDTSRRLAAEEGIFAGISAGATVATALS 275 >5XA2-A nrPDB Length = 309 Score = 36.2 bits (82), Expect = 0.020, Method: Compositional matrix adjust. Identities = 32/114 (28%), Positives = 54/114 (47%), Gaps = 19/114 (16%) Query: 24 HLTPVLTSSILNQIAGRNLFF--KCELFQKTGSFKIRGALNAIRGLIPDTLEGKPKA--- 78 LT L+S +L +I GRN + KC + G+ I A + GK K Sbjct: 21 RLTAGLSSRVLAKIEGRNPAYSVKCRI----GAAMIWDAEQS----------GKLKPGMH 66 Query: 79 VVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPNCKKLAIQAYGASIVYSEPSD 132 VV +SGN G AL + G + +P+T +++ ++++GA +V + +D Sbjct: 67 VVEPTSGNTGIALAFVCAARGYKLTLTMPETMSIERRMMLKSFGADLVLTPGAD 120 >5XCN-X nrPDB Length = 350 Score = 36.2 bits (82), Expect = 0.023, Method: Compositional matrix adjust. Identities = 27/100 (27%), Positives = 45/100 (45%) Query: 41 NLFFKCELFQKTGSFKIRGALNAIRGLIPDTLEGKPKAVVTHSSGNHGQALTYAAKLEGI 100 N+ K E + S K R N + D K K +V +SGN G AL Y A G Sbjct: 61 NVVVKIEGRNPSYSVKCRIGANMVWQAEKDGTLTKGKEIVDATSGNTGIALAYVAAARGY 120 Query: 101 PAYIVVPQTAPNCKKLAIQAYGASIVYSEPSDESRENVAQ 140 + +P+T +K + G ++V +E + ++ +A+ Sbjct: 121 KITLTMPETMSLERKRLLCGLGVNLVLTEGAKGAKGAIAK 160 >5KIN-B nrPDB Length = 407 Score = 35.4 bits (80), Expect = 0.033, Method: Compositional matrix adjust. Identities = 53/191 (27%), Positives = 81/191 (42%), Gaps = 28/191 (14%) Query: 26 TPVLTSSILNQ-IAGRNLFFKCELFQKTGSFKIRGALNAIRGLIPDTLEGKPKAVVTHSS 84 TP+ + L Q I G ++ K E TG+ KI AL + + + GK K + + Sbjct: 60 TPLYYAKNLTQHIGGAKIYLKREDLNHTGAHKINNALGQV--WLAKRM-GKKKIIAETGA 116 Query: 85 GNHGQALTYAAKLEGIPAYIVVPQTAPNCKKLAIQAYGASIVYSEP---SDESRE----- 136 G HG A AA L + I + + + K+ A+ + ++ ++ +D SR Sbjct: 117 GQHGVATATAAALFNMECTIYMGEE--DVKRQALNVFRMELLGAKVEAVTDGSRVLKDAV 174 Query: 137 NVAQRI----IQETEGIL---VHPNQEPAVIAG-QGTIALEVLNQV------PLVDALVV 182 N A R I +T IL + P+ P ++ Q I E Q L DALV Sbjct: 175 NAALRSWVANIDDTHYILGSALGPHPFPEIVRDFQSVIGREAKQQYRDLTGRDLPDALVA 234 Query: 183 PVGGGGMVAGI 193 VGGG G+ Sbjct: 235 CVGGGSNAIGL 245 >5OCW-B nrPDB Length = 442 Score = 34.7 bits (78), Expect = 0.060, Method: Compositional matrix adjust. Identities = 48/188 (25%), Positives = 79/188 (42%), Gaps = 23/188 (12%) Query: 26 TPVLTSSILNQIAGR-NLFFKCELFQKTGSFKIRGALNAIRGLIPDTLEGKPKAVVTHSS 84 +P+ ++ L+Q AG +F K E TGS KI L + L+ + GK + + + Sbjct: 102 SPLYEATRLSQHAGSARIFLKREDLNHTGSHKINNVLG--QALLARRM-GKTRVIAETGA 158 Query: 85 GNHGQALTYAAKLEGIPAYIVVP--QTAPNCKKLA-IQAYGASIVYSEPSDESRENVAQR 141 G HG A A L G+ I + TA +A ++ GA +V + ++ ++ Sbjct: 159 GQHGVATATACALLGLDCVIYMGGIDTARQALNVARMRLLGAEVVAVQTGSKTLKDAINE 218 Query: 142 IIQE----------TEGILVHPNQEPAVIAG-QGTIALEVLNQVP-----LVDALVVPVG 185 ++ G P+ P ++ Q I +E Q+ L DA+V VG Sbjct: 219 AFRDWVANADNTYYCFGTAAGPHPFPTMVRDFQRIIGMEARVQIQGQAGRLPDAVVACVG 278 Query: 186 GGGMVAGI 193 GG GI Sbjct: 279 GGSNAIGI 286 >5XEM-A nrPDB Length = 310 Score = 33.5 bits (75), Expect = 0.12, Method: Compositional matrix adjust. Identities = 46/181 (25%), Positives = 79/181 (43%), Gaps = 5/181 (2%) Query: 39 GRNLFFKCELFQKTGSFKIRGALNAIRGLIPDTLEGKPKAVVTHSSGNHGQALTYAAKLE 98 G ++ K E S K R AL I + L K ++ +SGN G L ++ Sbjct: 29 GNEIYVKLEGSNPGRSTKDRIALKMIEEAEKEGLIDKDTVIIEATSGNTGIGLAMICAVK 88 Query: 99 GIPAYIVVPQTAPNCKKLAIQAYGASIVYSEPSDESRENVAQ-RIIQETEGILVHPNQEP 157 IV+P T + ++AYG ++ ++ S + + + +++ E PNQ Sbjct: 89 NYKLKIVMPDTMSIERIQLMRAYGTEVILTDGSLGMKACLEKLEELKKNEKKYFVPNQFT 148 Query: 158 AV---IAGQGTIALEVLNQV-PLVDALVVPVGGGGMVAGIAITIKTLKPSVKVYAAEPSN 213 V A T A E+L + VD + G GG +G A +K P++K + EP++ Sbjct: 149 NVNNPKAHYETTAEEILKDLNNKVDVFICGTGTGGSFSGTAKKLKEKLPNIKTFPVEPAS 208 Query: 214 A 214 + Sbjct: 209 S 209 >5EY5-B nrPDB Length = 399 Score = 33.5 bits (75), Expect = 0.15, Method: Compositional matrix adjust. Identities = 46/192 (23%), Positives = 80/192 (41%), Gaps = 31/192 (16%) Query: 26 TPV-LTSSILNQIAGRNLFFKCELFQKTGSFKIRGALNAIRGLIPDTLEGKPKAVVTHSS 84 TP+ ++ + G ++ K E TG+ KI AL + L+ + GK + + + Sbjct: 51 TPLYFAENLTKDLGGAKIYLKREDLNHTGAHKINNALG--QALLAKRM-GKKRVIAETGA 107 Query: 85 GNHGQALTYAAKLEGIPAYIVVPQTAPNCKKLAIQAY--------------GASIVYSEP 130 G HG A A + G+ VV A + ++ A+ + G+ + Sbjct: 108 GQHGVATATVAAMFGLEC--VVYMGAEDIERQALNVFRMKLLGAKVRPVTSGSRTLKDAI 165 Query: 131 SDESRENVAQRIIQETE---GILVHPNQEPAVIAG-QGTIALEVLNQV-----PLVDALV 181 ++ R+ V +++T G +V P+ P ++ Q I E Q+ L DA+V Sbjct: 166 NEAMRDWVTN--VEDTFYIIGSVVGPHPYPMMVRDFQSVIGEEARQQILEKEGRLPDAIV 223 Query: 182 VPVGGGGMVAGI 193 VGGG GI Sbjct: 224 ACVGGGSNAMGI 235 >4LMB-A nrPDB Length = 322 Score = 33.1 bits (74), Expect = 0.20, Method: Compositional matrix adjust. Identities = 63/223 (28%), Positives = 100/223 (44%), Gaps = 21/223 (9%) Query: 79 VVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPNCKKLAIQAYGASIVYSEPSDESRENV 138 +V +SGN G AL A +G + +P+T ++ ++AYGA + + P + E Sbjct: 77 LVEPTSGNTGIALAMVAAAKGYRLVLTMPETMSLERRAMLKAYGAQLELT-PGSQGMEGA 135 Query: 139 ---AQRIIQET-EGILVHPNQEPAVIA-GQGTIALEVLNQVP-LVDALVVPVGGGGMVAG 192 A+ I++ T + + PA + T A E+ LVD ++ VG GG + G Sbjct: 136 ITRAEEIVENTPNAYSLQQFRNPANPKIHRETTAEEIWADTDGLVDIVIGGVGTGGTITG 195 Query: 193 IAITIKTLKPSVKVYAAEPSNADDCYQSKLKGELTPNLHPPETIADGVKSSIGLNTWPII 252 IA TIK +P + A EPSN+ + P H + I G +I Sbjct: 196 IAETIKPRRPQFQAIAVEPSNSPVLSGGQ------PGPHKIQGIGAGFIPAI------FR 243 Query: 253 RDLVDDVFTVTEDE-IKYATQLVWERMKLLIEPTAGVGLAAVL 294 +L+D+V V + E YA +L + LL +AG L A + Sbjct: 244 PELIDEVIIVDDTEAFAYARRLARQE-GLLSGISAGAALWAAI 285 >4AEC-A nrPDB Length = 430 Score = 32.3 bits (72), Expect = 0.29, Method: Compositional matrix adjust. Identities = 35/127 (27%), Positives = 60/127 (47%), Gaps = 19/127 (14%) Query: 17 LNIQDSV----HLTPVLTSSILNQIAG---RNLFFKCELFQKTGSFKIRGALNAI----- 64 LNI D+V TP++ LN IA N+ K E+ + S K R + + Sbjct: 111 LNIADNVSQLIGKTPMV---YLNSIAKGCVANIAAKLEIMEPCCSVKDRIGYSMVTDAEQ 167 Query: 65 RGLIPDTLEGKPKAVVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPNCKKLAIQAYGAS 124 +G I GK +V +SGN G L + A G + +P + +++ ++A+GA Sbjct: 168 KGFISP---GK-SVLVEPTSGNTGIGLAFIAASRGYRLILTMPASMSMERRVLLKAFGAE 223 Query: 125 IVYSEPS 131 +V ++P+ Sbjct: 224 LVLTDPA 230 >1X1Q-A nrPDB Length = 418 Score = 32.0 bits (71), Expect = 0.41, Method: Compositional matrix adjust. Identities = 45/192 (23%), Positives = 83/192 (43%), Gaps = 31/192 (16%) Query: 26 TPVLTSSILNQI-AGRNLFFKCELFQKTGSFKIRGALNAIRGLIPDTLEGKPKAVVTHSS 84 TP+ + L++ G +F K E TG+ KI L + L+ + GK + + + Sbjct: 78 TPLYHAKRLSEYWGGAQVFLKREDLLHTGAHKINNTLG--QALLARRM-GKRRVIAETGA 134 Query: 85 GNHGQALTYAAKLEGIPAYIVVPQTAPNCKKLAIQAYGASIVYSEP----------SDES 134 G HG ++ A L G+ VV + ++ A+ + ++ +E D + Sbjct: 135 GQHGVSVATVAALFGLEC--VVYMGEEDVRRQALNVFRMKLLGAEVRPVAAGSRTLKDAT 192 Query: 135 RENVAQRI--IQETEGIL---VHPNQEPAVIAGQGTI--------ALEVLNQVPLVDALV 181 E + I ++ T IL V P+ P ++ ++ +LE+ ++P DAL+ Sbjct: 193 NEAIRDWITNVRTTFYILGSVVGPHPYPMMVRDFQSVIGEEVKRQSLELFGRLP--DALI 250 Query: 182 VPVGGGGMVAGI 193 VGGG G+ Sbjct: 251 AAVGGGSNAIGL 262 >4ZW2-A nrPDB Length = 333 Score = 30.0 bits (66), Expect = 1.5, Method: Compositional matrix adjust. Identities = 12/29 (41%), Positives = 16/29 (55%) Query: 83 SSGNHGQALTYAAKLEGIPAYIVVPQTAP 111 SS HG+ + + K E +P Y VVP P Sbjct: 119 SSSKHGKRIPFFKKTEHVPPYDVVPSMRP 147 >3T4P-A nrPDB Length = 334 Score = 29.6 bits (65), Expect = 1.9, Method: Compositional matrix adjust. Identities = 13/50 (26%), Positives = 27/50 (54%) Query: 79 VVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPNCKKLAIQAYGASIVYS 128 VV SSGN G +L + + G I +P++ ++ ++ +GA ++ + Sbjct: 75 VVESSSGNTGVSLAHLGAIRGYKVIITMPESMSLERRCLLRIFGAEVILT 124 >5BPF-A nrPDB Length = 306 Score = 29.3 bits (64), Expect = 2.3, Method: Compositional matrix adjust. Identities = 17/49 (34%), Positives = 28/49 (57%), Gaps = 7/49 (14%) Query: 262 VTEDEIKYATQLVWERMKLLIEPTAGVGLAAVLSQHFQTVSPEVKNICI 310 +T D+++ T+LVW+ + L I P A+ Q F+T+SPE C+ Sbjct: 93 LTMDKLR--TKLVWQALGLPISP-----YVALNRQQFETLSPEELVACV 134 >1NKU-A nrPDB Length = 187 Score = 29.3 bits (64), Expect = 2.3, Method: Compositional matrix adjust. Identities = 33/128 (25%), Positives = 48/128 (37%), Gaps = 13/128 (10%) Query: 7 ISFADVEKAHLNIQDSVH-LTPVLTSSILNQIAGRNLFFKCELFQKTGSFKIRGALNAI- 64 +S+ V K N + H PV +++ + R L Q G + RG + AI Sbjct: 44 LSWITVLKKRENYRACFHQFDPVKVAAMQEEDVER-------LVQDAGIIRHRGKIQAII 96 Query: 65 ---RGLIPDTLEGKPKAVVTHSSGNHGQALTYAAKLEGIPAYIVVPQT-APNCKKLAIQA 120 R + G+P A S NH +T A L IP + KK + Sbjct: 97 GNARAYLQMEQNGEPFADFVWSFVNHQPQMTQATTLSEIPTSTPASDALSKALKKRGFKF 156 Query: 121 YGASIVYS 128 G +I YS Sbjct: 157 VGTTICYS 164 >6DQP-A nrPDB Length = 190 Score = 28.9 bits (63), Expect = 3.0, Method: Compositional matrix adjust. Identities = 25/94 (26%), Positives = 44/94 (46%), Gaps = 7/94 (7%) Query: 143 IQETEGILVHPNQEPAVIAGQGTIALEVLNQVPLVDALVVPVGGGGMVAGIAITIKTLKP 202 +Q+ +G++V A +G L++L + L +V+P+ GG VA + + + LKP Sbjct: 64 LQQADGLIVATPVYKAAYSGALKTLLDLLPERALQGKVVLPLATGGTVAHL-LAVDALKP 122 Query: 203 SVKVYAAEP----SNADD--CYQSKLKGELTPNL 230 + A+ ADD + + TPNL Sbjct: 123 VLSALKAQEILHGVFADDSQVIDYHHRPQFTPNL 156 >6AMI-A nrPDB Length = 396 Score = 28.1 bits (61), Expect = 5.0, Method: Compositional matrix adjust. Identities = 42/188 (22%), Positives = 73/188 (38%), Gaps = 23/188 (12%) Query: 26 TPVLTSSILNQ-IAGRNLFFKCELFQKTGSFKIRGALNAIRGLIPDTLEGKPKAVVTHSS 84 TP+ + L + I G ++ K E G+ K NAI + GK + + + Sbjct: 51 TPLYYAKRLTEKIGGAKVYLKREDLVHGGAHKTN---NAIGQALLAKFMGKTRLIAETGA 107 Query: 85 GNHGQALTYAAKLEGIPAYIVVPQTAPNCKKLAI---QAYGASIVYSEPSDESRENVAQR 141 G HG A A L G+ I + +K+ + + GA+++ + ++ Sbjct: 108 GQHGVATAMAGALLGMKVDIYMGAEDVERQKMNVFRMKLLGANVIPVNSGSRTLKDAINE 167 Query: 142 IIQE----------TEGILVHPNQEPAVIAG-QGTIALEVLNQV-----PLVDALVVPVG 185 +++ G +V P+ P ++ Q I E Q+ L D +V VG Sbjct: 168 ALRDWVATFEYTHYLIGSVVGPHPYPTIVRDFQSVIGREAKAQILEAEGQLPDVIVACVG 227 Query: 186 GGGMVAGI 193 GG GI Sbjct: 228 GGSNAMGI 235 >2DZD-A nrPDB Length = 461 Score = 27.7 bits (60), Expect = 7.0, Method: Compositional matrix adjust. Identities = 20/75 (26%), Positives = 35/75 (46%) Query: 106 VPQTAPNCKKLAIQAYGASIVYSEPSDESRENVAQRIIQETEGILVHPNQEPAVIAGQGT 165 V + K A A+G+ VY E E+ +++ +I+ + EG +VH + + + Sbjct: 182 VKEAFERAKSEAKAAFGSDEVYVEKLIENPKHIEVQILGDYEGNIVHLYERDCSVQRRHQ 241 Query: 166 IALEVLNQVPLVDAL 180 +EV V L D L Sbjct: 242 KVVEVAPSVSLSDEL 256 >4AJN-A nrPDB Length = 331 Score = 27.3 bits (59), Expect = 8.4, Method: Compositional matrix adjust. Identities = 20/59 (33%), Positives = 26/59 (44%), Gaps = 8/59 (13%) Query: 173 QVPLVDALVVPVGGGGMVAGIAITIKTLKPSVKVYAAEPSNADDCYQSKLKGELTPNLH 231 QVP VV VG GM I+I +K L + + D + KLKGE+ H Sbjct: 16 QVPQNKITVVGVGAVGMACAISILMKDLADELALV--------DVIEDKLKGEMMDLQH 66 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 3L6C-A nrPDB 448 e-126 5X2L-A nrPDB 436 e-123 5YBW-A nrPDB 310 5e-85 5CVC-A nrPDB 285 3e-77 1V71-A nrPDB 281 2e-76 1TDJ-A nrPDB 273 8e-74 4COO-A nrPDB 268 2e-72 1M54-A nrPDB 267 4e-72 3IAU-A nrPDB 267 5e-72 5MMS-A nrPDB 266 9e-72 5OHX-A nrPDB 263 1e-70 2GN1-A nrPDB 256 7e-69 1VE5-A nrPDB 249 1e-66 3FCA-A nrPDB 245 1e-65 5C3U-A nrPDB 241 5e-64 4LMA-A nrPDB 238 3e-63 3PC3-A nrPDB 234 4e-62 6C2H-A nrPDB 234 4e-62 2BHS-A nrPDB 233 1e-61 1PWH-A nrPDB 231 3e-61 2Q3D-A nrPDB 230 5e-61 2JC3-A nrPDB 230 5e-61 2EFY-A nrPDB 230 6e-61 5JJC-A nrPDB 228 3e-60 6AHI-A nrPDB 227 4e-60 4H27-A nrPDB 225 2e-59 4OFX-A nrPDB 223 8e-59 2PQM-A nrPDB 219 1e-57 4I1Y-A nrPDB 219 1e-57 2RKB-A nrPDB 213 1e-55 6NMX-A nrPDB 211 4e-55 5D84-A nrPDB 196 9e-51 5I7O-A nrPDB 191 5e-49 5B1I-A nrPDB 186 1e-47 2ZSJ-A nrPDB 185 3e-47 2D1F-A nrPDB 178 3e-45 5B55-A nrPDB 177 6e-45 5YGR-A nrPDB 170 8e-43 1UIN-A nrPDB 170 9e-43 4D9G-A nrPDB 157 8e-39 Sequences not found previously or not previously below threshold: 3VBE-A nrPDB 215 2e-56 4AEC-A nrPDB 214 3e-56 5XA2-A nrPDB 214 5e-56 2EGU-A nrPDB 214 5e-56 5XW3-A nrPDB 211 3e-55 5J5V-A nrPDB 206 1e-53 2ISQ-A nrPDB 206 2e-53 4LMB-A nrPDB 203 7e-53 5XEM-A nrPDB 202 2e-52 3X43-A nrPDB 184 3e-47 3T4P-A nrPDB 184 4e-47 5XCN-X nrPDB 175 2e-44 3VSD-A nrPDB 118 3e-27 1E5X-A nrPDB 118 4e-27 6HUL-B nrPDB 98 6e-21 5EY5-B nrPDB 94 8e-20 5OCW-B nrPDB 90 1e-18 5KZM-B nrPDB 89 3e-18 5KIN-B nrPDB 88 5e-18 4D9F-A nrPDB 87 8e-18 6AMI-A nrPDB 86 3e-17 1X1Q-A nrPDB 85 5e-17 1CX9-B nrPDB 84 8e-17 4NEG-A nrPDB 84 1e-16 3SS9-X nrPDB 74 8e-14 1J0B-A nrPDB 73 2e-13 3R0X-A nrPDB 71 9e-13 1RQX-A nrPDB 69 2e-12 6EQN-B nrPDB 63 2e-10 1VB3-A nrPDB 61 6e-10 3V7N-A nrPDB 39 0.002 2VCY-A nrPDB 35 0.059 4F4F-A nrPDB 34 0.085 1KL7-A nrPDB 33 0.24 4G5X-A nrPDB 32 0.29 3X0D-A nrPDB 32 0.51 1YIQ-A nrPDB 30 1.1 2H6E-A nrPDB 30 1.4 4EB7-A nrPDB 30 1.6 4REV-A nrPDB 30 1.6 3OM8-A nrPDB 30 1.6 3NXS-A nrPDB 30 1.7 3NJR-A nrPDB 30 1.8 1PFK-A nrPDB 29 2.2 5OC1-A nrPDB 29 2.6 1X1H-A nrPDB 29 3.4 2W37-A nrPDB 29 3.7 3JSK-A nrPDB 29 3.9 4W8I-A nrPDB 29 4.0 3RP7-A nrPDB 29 4.4 1WCV-1 nrPDB 29 4.7 5Y2D-A nrPDB 28 5.0 5DTE-A nrPDB 28 5.7 5Y28-A nrPDB 28 5.7 2OTN-A nrPDB 28 7.4 6B6X-A nrPDB 28 8.0 1QE0-A nrPDB 27 8.3 3E05-A nrPDB 27 8.4 2DFV-A nrPDB 27 9.8 >3L6C-A nrPDB Length = 339 Score = 448 bits (1151), Expect = e-126, Method: Composition-based stats. Identities = 331/333 (99%), Positives = 331/333 (99%) Query: 1 MCAQYCISFADVEKAHLNIQDSVHLTPVLTSSILNQIAGRNLFFKCELFQKTGSFKIRGA 60 M AQY ISFADVEKAHLNIQDSVHLTPVLTSSILNQIAGRNLFFKCELFQKTGSFKIRGA Sbjct: 1 MDAQYDISFADVEKAHLNIQDSVHLTPVLTSSILNQIAGRNLFFKCELFQKTGSFKIRGA 60 Query: 61 LNAIRGLIPDTLEGKPKAVVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPNCKKLAIQA 120 LNAIRGLIPDTLEGKPKAVVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPNCKKLAIQA Sbjct: 61 LNAIRGLIPDTLEGKPKAVVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPNCKKLAIQA 120 Query: 121 YGASIVYSEPSDESRENVAQRIIQETEGILVHPNQEPAVIAGQGTIALEVLNQVPLVDAL 180 YGASIVYSEPSDESRENVAQRIIQETEGILVHPNQEPAVIAGQGTIALEVLNQVPLVDAL Sbjct: 121 YGASIVYSEPSDESRENVAQRIIQETEGILVHPNQEPAVIAGQGTIALEVLNQVPLVDAL 180 Query: 181 VVPVGGGGMVAGIAITIKTLKPSVKVYAAEPSNADDCYQSKLKGELTPNLHPPETIADGV 240 VVPVGGGGMVAGIAITIKTLKPSVKVYAAEPSNADDCYQSKLKGELTPNLHPPETIADGV Sbjct: 181 VVPVGGGGMVAGIAITIKTLKPSVKVYAAEPSNADDCYQSKLKGELTPNLHPPETIADGV 240 Query: 241 KSSIGLNTWPIIRDLVDDVFTVTEDEIKYATQLVWERMKLLIEPTAGVGLAAVLSQHFQT 300 KSSIGLNTWPIIRDLVDDVFTVTEDEIKYATQLVWERMKLLIEPTAGVGLAAVLSQHFQT Sbjct: 241 KSSIGLNTWPIIRDLVDDVFTVTEDEIKYATQLVWERMKLLIEPTAGVGLAAVLSQHFQT 300 Query: 301 VSPEVKNICIVLSGGNVDLTSLSWVKQAERPAP 333 VSPEVKNICIVLSGGNVDLTSLSWVKQAERPAP Sbjct: 301 VSPEVKNICIVLSGGNVDLTSLSWVKQAERPAP 333 >5X2L-A nrPDB Length = 348 Score = 436 bits (1121), Expect = e-123, Method: Composition-based stats. Identities = 303/333 (90%), Positives = 323/333 (96%), Gaps = 1/333 (0%) Query: 1 MCAQYCISFADVEKAHLNIQDSVHLTPVLTSSILNQIAGRNLFFKCELFQKTGSFKIRGA 60 MCAQYCISFADVEKAH+NI+DS+HLTPVLTSSILNQ+ GRNLFFKCELFQKTGSFKIRGA Sbjct: 1 MCAQYCISFADVEKAHINIRDSIHLTPVLTSSILNQLTGRNLFFKCELFQKTGSFKIRGA 60 Query: 61 LNAIRGLIPDTLEGKPKAVVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPNCKKLAIQA 120 LNA+R L+PD LE KPKAVVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAP+CKKLAIQA Sbjct: 61 LNAVRSLVPDALERKPKAVVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPDCKKLAIQA 120 Query: 121 YGASIVYSEPSDESRENVAQRIIQETEGILVHPNQEPAVIAGQGTIALEVLNQVPLVDAL 180 YGASIVY EPSDESRENVA+R+ +ETEGI+VHPNQEPAVIAGQGTIALEVLNQVPLVDAL Sbjct: 121 YGASIVYCEPSDESRENVAKRVTEETEGIMVHPNQEPAVIAGQGTIALEVLNQVPLVDAL 180 Query: 181 VVPVGGGGMVAGIAITIKTLKPSVKVYAAEPSNADDCYQSKLKGELTPNLHPPETIADGV 240 VVPVGGGGM+AGIAIT+K LKPSVKVYAAEPSNADDCYQSKLKG+L PNL+PPETIADGV Sbjct: 181 VVPVGGGGMLAGIAITVKALKPSVKVYAAEPSNADDCYQSKLKGKLMPNLYPPETIADGV 240 Query: 241 KSSIGLNTWPIIRDLVDDVFTVTEDEIKYATQLVWERMKLLIEPTAGVGLAAVLSQHFQT 300 KSSIGLNTWPIIRDLVDD+FTVTEDEIK ATQLVWERMKLLIEPTAGVG+AAVLSQHFQT Sbjct: 241 KSSIGLNTWPIIRDLVDDIFTVTEDEIKCATQLVWERMKLLIEPTAGVGVAAVLSQHFQT 300 Query: 301 VSPEVKNICIVLSGGNVDL-TSLSWVKQAERPA 332 VSPEVKNICIVLSGGNVDL +S++WVKQAERPA Sbjct: 301 VSPEVKNICIVLSGGNVDLTSSITWVKQAERPA 333 >5YBW-A nrPDB Length = 329 Score = 310 bits (794), Expect = 5e-85, Method: Composition-based stats. Identities = 139/328 (42%), Positives = 190/328 (57%), Gaps = 9/328 (2%) Query: 4 QYCISFADVEKAHLNIQDSVHLTPVLTSSILNQI----AGRNLFFKCELFQKTGSFKIRG 59 Q+ ++ D++KA+ I + TPV TS +++ AGR +FK E QKTGSFK RG Sbjct: 3 QFEVTVTDIKKAYDRISKHILYTPVFTSPTFDRMVGSKAGRQFYFKAENLQKTGSFKARG 62 Query: 60 ALNAIRGLIPDTLEGKPKAVVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPNCKKLAIQ 119 ALNAI L E VVTHSSGNHGQAL +A+K G+ +VVP+TAP K A++ Sbjct: 63 ALNAI--LCALEREPSLAGVVTHSSGNHGQALAWASKRAGVKCCVVVPKTAPQVKFDAME 120 Query: 120 AYGASIVYSEPSDESRENVAQRIIQETEGILVHPNQEPAVIAGQGTIALEVLNQVPLVDA 179 YGA +V EP+ SR+ + + + + + + VIAGQGTIALE+L Q P +DA Sbjct: 121 NYGAEVVKCEPNPTSRKETCEGLAKSRGYKYISSSDDYDVIAGQGTIALELLQQQPDLDA 180 Query: 180 LVVPVGGGGMVAGIAITIKTLKPSVKVYAAEPSNADDCYQSKLKGELTPNLHP-PETIAD 238 ++V V GGM +GI + K K +KV+ EP + L PN +TIAD Sbjct: 181 ILVSVSAGGMASGICVYTKNTKSDLKVFLVEPEGKMLEECISKRERLWPNPPQFLDTIAD 240 Query: 239 GVK-SSIGLNTWPIIRDLVD-DVFTVTEDEIKYATQLVWERMKLLIEPTAGVGLAAVLSQ 296 G+ G TWPII +L + +V TV D I A + V+ RMKL+IE AG +AA +++ Sbjct: 241 GIILQQCGNKTWPIILELPEKEVITVNNDNIVEAMRFVFARMKLVIEAAAGATVAAAMTE 300 Query: 297 HFQTVSPEVKNICIVLSGGNVDLTSLSW 324 FQ PE K + I+L GGNVD+ L W Sbjct: 301 RFQNFHPEAKKVGIILCGGNVDIEKLPW 328 >5CVC-A nrPDB Length = 346 Score = 285 bits (728), Expect = 3e-77, Method: Composition-based stats. Identities = 147/328 (44%), Positives = 214/328 (65%), Gaps = 7/328 (2%) Query: 5 YCISFADVEKAHLNIQDSVHLTPVLTSSILNQIAGRNLFFKCELFQKTGSFKIRGALNAI 64 Y + +A I VH TPV++S+ ++ + G+ LFFKCE FQK G+FKIRGA N+I Sbjct: 16 YAADIDSIREAQARIAPYVHRTPVMSSTSIDAMVGKKLFFKCECFQKAGAFKIRGASNSI 75 Query: 65 RGLIPDTLEGKPKAVVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPNCKKLAIQAYGAS 124 L + + K VVTHSSGNH A+ AAKL GIPA+IV+P+ AP K ++ YG Sbjct: 76 FALDDEQVS---KGVVTHSSGNHAAAVALAAKLRGIPAHIVIPRNAPASKVENVKCYGGH 132 Query: 125 IVYSEPSDESRENVAQRIIQETEGILVHPNQEPAVIAGQGTIALEVLNQVPLVDALVVPV 184 I++S+ S ESRE V++R+ +ET +L+HP I+GQGT++LE+L QVP +D ++VP+ Sbjct: 133 IIWSDASIESREYVSKRVQEETGAVLIHPINSKYTISGQGTVSLELLEQVPEIDTIIVPI 192 Query: 185 GGGGMVAGIAITIKTLKPSVKVYAAEPSNADDCYQSKLKGELTPNLHPPETIADGVKSSI 244 GGG+++G+A+ K + PS+++ AAEP ADD QSK G++ L TIADG+++ + Sbjct: 193 SGGGLISGVALAAKAINPSIRILAAEPKGADDSAQSKAAGKII-TLPSTNTIADGLRAFL 251 Query: 245 GLNTWPIIRDLVDDVFTVTEDEIKYATQLVWERMKLLIEPTAGVGLAAVLSQHFQTVSP- 303 G TWP++RDLVDDV V + I A ++ +E +K+ +EP+ +GLAA LS F+ S Sbjct: 252 GDLTWPVVRDLVDDVIVVDDTAIVDAMKMCYEILKVAVEPSGAIGLAAALSDEFKQSSAW 311 Query: 304 -EVKNICIVLSGGNVDLTSLSWVKQAER 330 E I I++SGGNVDL +L W + Sbjct: 312 HESSKIGIIVSGGNVDLGTL-WQSMYKH 338 >1V71-A nrPDB Length = 323 Score = 281 bits (720), Expect = 2e-76, Method: Composition-based stats. Identities = 121/315 (38%), Positives = 184/315 (58%), Gaps = 8/315 (2%) Query: 8 SFADVEKAHLNIQDSVHLTPVLTSSILNQIAGRNLFFKCELFQKTGSFKIRGALNAIRGL 67 ++ DV A I+ + TPVLTSS +N+ +FFKCE FQK G+FK RGALNA+ L Sbjct: 9 TYDDVASASERIKKFANKTPVLTSSTVNKEFVAEVFFKCENFQKMGAFKFRGALNALSQL 68 Query: 68 IPDTLEGKPKAVVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPNCKKLAIQAYGASIVY 127 + V+T SSGNH QA+ +AK+ GIPA I++P AP K A + YG ++ Sbjct: 69 NE---AQRKAGVLTFSSGNHAQAIALSAKILGIPAKIIMPLDAPEAKVAATKGYGGQVIM 125 Query: 128 SEPSDESRENVAQRIIQETEGILVHPNQEPAVIAGQGTIALEVLNQVPLVDALVVPVGGG 187 + + RE +A+ I + ++ P P V+AGQGT A E+ +V +DAL V +GGG Sbjct: 126 YDRYKDDREKMAKEISEREGLTIIPPYDHPHVLAGQGTAAKELFEEVGPLDALFVCLGGG 185 Query: 188 GMVAGIAITIKTLKPSVKVYAAEPSNADDCYQSKLKGELTPNLHPPETIADGVKSS-IGL 246 G+++G A+ + P+ +VY EP +D QS KG + ++ P+TIADG ++ +G Sbjct: 186 GLLSGSALAARHFAPNCEVYGVEPEAGNDGQQSFRKGSIV-HIDTPKTIADGAQTQHLGN 244 Query: 247 NTWPIIRDLVDDVFTVTEDEIKYATQLVWERMKLLIEPTAGVGLAAVLSQHFQTVSPEVK 306 T+ II++ VDD+ TV+++E+ + RMK+++EPT + AA + K Sbjct: 245 YTFSIIKEKVDDILTVSDEELIDCLKFYAARMKIVVEPTGCLSFAAA---RAMKEKLKNK 301 Query: 307 NICIVLSGGNVDLTS 321 I I++SGGNVD+ Sbjct: 302 RIGIIISGGNVDIER 316 >1TDJ-A nrPDB Length = 514 Score = 273 bits (698), Expect = 8e-74, Method: Composition-based stats. Identities = 95/310 (30%), Positives = 160/310 (51%), Gaps = 6/310 (1%) Query: 19 IQDSVHLTPVLTSSILNQIAGRNLFFKCELFQKTGSFKIRGALNAIRGLIPDTLEGKPKA 78 + ++ +TP+ L+ + K E Q SFK+RGA + GL T E K Sbjct: 25 VYEAAQVTPLQKMEKLSSRLDNVILVKREDRQPVHSFKLRGAYAMMAGL---TEEQKAHG 81 Query: 79 VVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPNCKKLAIQAYGASIVYSEPSDESRENV 138 V+T S+GNH Q + +++ G+ A IV+P + K A++ +G ++ + + + Sbjct: 82 VITASAGNHAQGVAFSSARLGVKALIVMPTATADIKVDAVRGFGGEVLLHGANFDEAKAK 141 Query: 139 AQRIIQETEGILVHPNQEPAVIAGQGTIALEVLNQVPLVDALVVPVGGGGMVAGIAITIK 198 A + Q+ V P P VIAGQGT+ALE+L Q +D + VPVGGGG+ AG+A+ IK Sbjct: 142 AIELSQQQGFTWVPPFDHPMVIAGQGTLALELLQQDAHLDRVFVPVGGGGLAAGVAVLIK 201 Query: 199 TLKPSVKVYAAEPSNADDCYQSKLKGELTPNLHPPETIADGVK-SSIGLNTWPIIRDLVD 257 L P +KV A E ++ + G +L A+GV IG T+ + ++ +D Sbjct: 202 QLMPQIKVIAVEAEDSACLKAALDAGHPV-DLPRVGLFAEGVAVKRIGDETFRLCQEYLD 260 Query: 258 DVFTVTEDEIKYATQLVWERMKLLIEPTAGVGLAAVLSQHFQTVSPEVKNICIVLSGGNV 317 D+ TV D I A + ++E ++ + EP+ + LA + ++ + + + +LSG NV Sbjct: 261 DIITVDSDAICAAMKDLFEDVRAVAEPSGALALAG-MKKYIALHNIRGERLAHILSGANV 319 Query: 318 DLTSLSWVKQ 327 + L +V + Sbjct: 320 NFHGLRYVSE 329 >4COO-A nrPDB Length = 563 Score = 268 bits (686), Expect = 2e-72, Method: Composition-based stats. Identities = 74/310 (23%), Positives = 122/310 (39%), Gaps = 23/310 (7%) Query: 18 NIQDSVHLTPVLTSSILNQIAG--RNLFFKCELFQKTGSFKIRGALNAIRGLIPDTLEGK 75 +I + TP++ + + + G L KCE F GS K R +L I D Sbjct: 101 DILKKIGDTPMVRINKIGKKFGLKCELLAKCEFFNAGGSVKDRISLRMIEDAERDGTLKP 160 Query: 76 PKAVVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPNCKKLAIQAYGASIVYSEPS---- 131 ++ +SGN G L AA + G IV+P+ + K ++A GA IV + + Sbjct: 161 GDTIIEPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDVLRALGAEIVRTPTNARFD 220 Query: 132 -DESRENVAQRIIQETEG-ILVHPNQEPAV-IAGQGTIALEVLNQVP-LVDALVVPVGGG 187 ES VA R+ E ++ + + +A T A E+L Q +D LV VG G Sbjct: 221 SPESHVGVAWRLKNEIPNSHILDQYRNASNPLAHYDTTADEILQQCDGKLDMLVASVGTG 280 Query: 188 GMVAGIAITIKTLKPSVKVYAAEPSNADDCYQSKLKGELTPNLHPPETIADGVKSSIGLN 247 G + GIA +K P ++ +P + P IG + Sbjct: 281 GTITGIARKLKEKCPGCRIIGVDPEGSILA---------EPEELNQTEQTTYEVEGIGYD 331 Query: 248 TWPII--RDLVDDVFTVTEDEIKYATQLVWERMKLLIEPTAGVGLAAVLSQHFQTVSPEV 305 P + R +VD F ++E +++ + LL +AG +A + E Sbjct: 332 FIPTVLDRTVVDKWFKSNDEEAFTFARMLIAQEGLLCGGSAGSTVAVAVK--AAQELQEG 389 Query: 306 KNICIVLSGG 315 + ++L Sbjct: 390 QRCVVILPDS 399 >1M54-A nrPDB Length = 363 Score = 267 bits (683), Expect = 4e-72, Method: Composition-based stats. Identities = 74/310 (23%), Positives = 122/310 (39%), Gaps = 23/310 (7%) Query: 18 NIQDSVHLTPVLTSSILNQIAG--RNLFFKCELFQKTGSFKIRGALNAIRGLIPDTLEGK 75 +I + TP++ + + + G L KCE F GS K R +L I D Sbjct: 36 DILKKIGDTPMVRINKIGKKFGLKCELLAKCEFFNAGGSVKDRISLRMIEDAERDGTLKP 95 Query: 76 PKAVVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPNCKKLAIQAYGASIVYSEPS---- 131 ++ +SGN G L AA + G IV+P+ + K ++A GA IV + + Sbjct: 96 GDTIIEPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDVLRALGAEIVRTPTNARFD 155 Query: 132 -DESRENVAQRIIQETEG-ILVHPNQEPAV-IAGQGTIALEVLNQVP-LVDALVVPVGGG 187 ES VA R+ E ++ + + +A T A E+L Q +D LV VG G Sbjct: 156 SPESHVGVAWRLKNEIPNSHILDQYRNASNPLAHYDTTADEILQQCDGKLDMLVASVGTG 215 Query: 188 GMVAGIAITIKTLKPSVKVYAAEPSNADDCYQSKLKGELTPNLHPPETIADGVKSSIGLN 247 G + GIA +K P ++ +P + P IG + Sbjct: 216 GTITGIARKLKEKCPGCRIIGVDPEGSILA---------EPEELNQTEQTTYEVEGIGYD 266 Query: 248 TWPII--RDLVDDVFTVTEDEIKYATQLVWERMKLLIEPTAGVGLAAVLSQHFQTVSPEV 305 P + R +VD F ++E +++ + LL +AG +A + E Sbjct: 267 FIPTVLDRTVVDKWFKSNDEEAFTFARMLIAQEGLLCGGSAGSTVAVAVK--AAQELQEG 324 Query: 306 KNICIVLSGG 315 + ++L Sbjct: 325 QRCVVILPDS 334 >3IAU-A nrPDB Length = 366 Score = 267 bits (682), Expect = 5e-72, Method: Composition-based stats. Identities = 94/310 (30%), Positives = 157/310 (50%), Gaps = 6/310 (1%) Query: 19 IQDSVHLTPVLTSSILNQIAGRNLFFKCELFQKTGSFKIRGALNAIRGLIPDTLEGKPKA 78 + D +P+ + L+ G N + K E Q+ SFK+RGA N + L + L+ K Sbjct: 54 VYDVAIESPLELAEKLSDRLGVNFYIKREDKQRVFSFKLRGAYNMMSNLSREELD---KG 110 Query: 79 VVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPNCKKLAIQAYGASIVYSEPSDESRENV 138 V+T S+GNH Q + A + A IV+P T P K A++A G +V + + + Sbjct: 111 VITASAGNHAQGVALAGQRLNCVAKIVMPTTTPQIKIDAVRALGGDVVLYGKTFDEAQTH 170 Query: 139 AQRIIQETEGILVHPNQEPAVIAGQGTIALEVLNQVPLVDALVVPVGGGGMVAGIAITIK 198 A + ++ + P +P VI GQGTI E+ Q+ + A+ +PVGGGG++AG+A K Sbjct: 171 ALELSEKDGLKYIPPFDDPGVIKGQGTIGTEINRQLKDIHAVFIPVGGGGLIAGVATFFK 230 Query: 199 TLKPSVKVYAAEPSNADDCYQSKLKGELTPNLHPPETIADGVKSS-IGLNTWPIIRDLVD 257 + P+ K+ EP A S +G L +T ADGV + +G T+ ++L+D Sbjct: 231 QIAPNTKIIGVEPYGAASMTLSLHEGHRV-KLSNVDTFADGVAVALVGEYTFAKCQELID 289 Query: 258 DVFTVTEDEIKYATQLVWERMKLLIEPTAGVGLAAVLSQHFQTVSPEVKNICIVLSGGNV 317 + V D I A + V++ + ++E T+G A + + + + +NI + SG N+ Sbjct: 290 GMVLVANDGISAAIKDVYDEGRNILE-TSGAVAIAGAAAYCEFYKIKNENIVAIASGANM 348 Query: 318 DLTSLSWVKQ 327 D + L V + Sbjct: 349 DFSKLHKVTE 358 >5MMS-A nrPDB Length = 408 Score = 266 bits (680), Expect = 9e-72, Method: Composition-based stats. Identities = 74/316 (23%), Positives = 124/316 (39%), Gaps = 23/316 (7%) Query: 18 NIQDSVHLTPVLTSSILNQIAG--RNLFFKCELFQKTGSFKIRGALNAIRGLIPDTLEGK 75 +I + TP++ + + + G L KCE F GS K R +L I D Sbjct: 79 DILKKIGDTPMVRINKIGKKFGLKCELLAKCEFFNAGGSVKDRISLRMIEDAERDGTLKP 138 Query: 76 PKAVVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPNCKKLAIQAYGASIVYSEPS---- 131 ++ +SGN G L AA + G IV+P+ + K ++A GA IV + + Sbjct: 139 GDTIIEPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDVLRALGAEIVRTPTNARFD 198 Query: 132 -DESRENVAQRIIQETEG-ILVHPNQEPAV-IAGQGTIALEVLNQVP-LVDALVVPVGGG 187 ES VA R+ E ++ + + +A T A E+L Q +D LV VG G Sbjct: 199 SPESHVGVAWRLKNEIPNSHILDQYRNASNPLAHYDTTADEILQQCDGKLDMLVASVGTG 258 Query: 188 GMVAGIAITIKTLKPSVKVYAAEPSNADDCYQSKLKGELTPNLHPPETIADGVKSSIGLN 247 G + GIA +K P ++ +P + P IG + Sbjct: 259 GTITGIARKLKEKCPGCRIIGVDPEGSILA---------EPEELNQTEQTTYEVEGIGYD 309 Query: 248 TWPII--RDLVDDVFTVTEDEIKYATQLVWERMKLLIEPTAGVGLAAVLSQHFQTVSPEV 305 P + R +VD F ++E +++ + LL +AG +A + E Sbjct: 310 FIPTVLDRTVVDKWFKSNDEEAFTFARMLIAQEGLLCGGSAGSTVAVAVK--AAQELQEG 367 Query: 306 KNICIVLSGGNVDLTS 321 + ++L + + Sbjct: 368 QRCVVILPDSVRNYMT 383 >5OHX-A nrPDB Length = 504 Score = 263 bits (671), Expect = 1e-70, Method: Composition-based stats. Identities = 80/330 (24%), Positives = 141/330 (42%), Gaps = 25/330 (7%) Query: 11 DVEKAHLNIQDSVHLTPVLTSSILNQIAG--RNLFFKCELFQKTGSFKIRGALNAIRGLI 68 D K +I ++ TP++ + + + G ++ KCE GS K R A I+ Sbjct: 31 DYTKIMPDILTAIGQTPLIKLNNIPKSYGIKCEIYAKCEFLNPGGSVKDRIAYRMIQDAE 90 Query: 69 PDTLEGKPKAVVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPNCKKLAIQAYGASIVYS 128 L ++ +SGN G L AA + G IV+P+ + K + A GA I+ + Sbjct: 91 DKGLLKPGCTIIEPTSGNTGIGLAMAAAVRGYKCIIVMPEKMSDEKISTLYALGAKIIRT 150 Query: 129 EP-----SDESRENVAQRIIQETEG-ILVHPNQEPAV-IAGQGTIALEVLNQV-PLVDAL 180 S E+ +VAQ++ +E I++ P +A A+E+ Q +D L Sbjct: 151 PTEASWHSPEAHISVAQKLQKEIPNSIILDQYTNPGNPLAHYDQTAIEIWKQCEGKIDYL 210 Query: 181 VVPVGGGGMVAGIAITIKTLKPSVKVYAAEPSNADDCYQSKLKGELTPNLHPPETIADGV 240 V G GG ++GI +K L P++K+ A +P + L P+ + Sbjct: 211 VAGAGTGGTISGIGRKLKELSPNIKIIAVDPKGSI----------LDPSSDSQNEVGFYE 260 Query: 241 KSSIGLNTWPII--RDLVDDVFTVTEDEIKYATQLVWERMKLLIEPTAGVGLAAVLSQHF 298 IG + P + R+++D ++E A +++ + LL ++G L A L Sbjct: 261 VEGIGYDFIPTVLDRNVIDKWIKTEDNESLNAARMLIRQEGLLCGGSSGAALIAALKIAK 320 Query: 299 QTVSPEVKNICIVLSGGNVDLTSLSWVKQA 328 PE K + I+L G + + +V + Sbjct: 321 D--IPEEKRMVIILPDGIRNYLT-KFVSEY 347 >2GN1-A nrPDB Length = 342 Score = 256 bits (655), Expect = 7e-69, Method: Composition-based stats. Identities = 111/321 (34%), Positives = 175/321 (54%), Gaps = 6/321 (1%) Query: 7 ISFADVEKAHLNIQDSVHLTPVLTSSILNQIAGRNLFFKCELFQKTGSFKIRGALNAIRG 66 ++ D+ +A + ++ T + S+ ++ +F K E Q+TGSFKIRGA N + Sbjct: 22 VAIEDILEAKKRLAGKIYKTGMPRSNYFSERCKGEIFLKFENMQRTGSFKIRGAFNKLSS 81 Query: 67 LIPDTLEGKPKAVVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPNCKKLAIQAYGASIV 126 L T K K VV S+GNH Q ++ + + GI +V+P+ AP K A Y A +V Sbjct: 82 L---TEAEKRKGVVACSAGNHAQGVSLSCAMLGIDGKVVMPKGAPKSKVAATCDYSAEVV 138 Query: 127 YSEPSDESRENVAQRIIQETEGILVHPNQEPAVIAGQGTIALEVLNQVPLVDALVVPVGG 186 + I++ I + P +P VIAGQGTI LE++ + VD ++VP+GG Sbjct: 139 LHGDNFNDTIAKVSEIVETEGRIFIPPYDDPKVIAGQGTIGLEIMEDLYDVDNVIVPIGG 198 Query: 187 GGMVAGIAITIKTLKPSVKVYAAEPSNADDCYQSKLKGELTPNLHPPETIADGVK-SSIG 245 GG++AGIAI IK++ P++KV + N S GE+T + T+ADG S G Sbjct: 199 GGLIAGIAIAIKSINPTIKVIGVQAENVHGMAASYYTGEITTH-RTTGTLADGCDVSRPG 257 Query: 246 LNTWPIIRDLVDDVFTVTEDEIKYATQLVWERMKLLIEPTAGVGLAAVLSQHFQTVSPEV 305 T+ I+R+LVDD+ V+EDEI+ + + +R K++ E + AA+LS + Sbjct: 258 NLTYEIVRELVDDIVLVSEDEIRNSMIALIQRNKVITEGAGALACAALLSGKLDSHIQNR 317 Query: 306 KNICIVLSGGNVDLTSLSWVK 326 K + I+ SGGN+DL+ +S + Sbjct: 318 KTVSII-SGGNIDLSRVSQIT 337 >1VE5-A nrPDB Length = 311 Score = 249 bits (636), Expect = 1e-66, Method: Composition-based stats. Identities = 128/318 (40%), Positives = 187/318 (58%), Gaps = 15/318 (4%) Query: 8 SFADVEKAHLNIQDSVHLTPVLTSSILNQIAGRNLFFKCELFQKTGSFKIRGALNAIRGL 67 S D+ A I H TP+LTS +L+ + G+ L K E QKTGSFK RGAL+ L Sbjct: 3 SLQDLYAAFRRIAPYTHRTPLLTSRLLDGLLGKRLLLKAEHLQKTGSFKARGALSKALAL 62 Query: 68 IPDTLEGKPKAVVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPNCKKLAIQAYGASIVY 127 PK ++ SSGNH Q + YAA++ G+ A +V+P+ A KK +AYGA +V Sbjct: 63 ------ENPKGLLAVSSGNHAQGVAYAAQVLGVKALVVMPEDASPYKKACARAYGAEVVD 116 Query: 128 SEPSDESRENVAQRIIQETEGILVHPNQEPAVIAGQGTIALEVLNQVPLV----DALVVP 183 + ++RE VA+ + +ET L+HP +P VIAGQGT LE+L Q + A++ P Sbjct: 117 RGVTAKNREEVARALQEETGYALIHPFDDPLVIAGQGTAGLELLAQAGRMGVFPGAVLAP 176 Query: 184 VGGGGMVAGIAITIKTLKPSVKVYAAEPSNADDCYQSKLKGELTPNLHPPETIADGVKS- 242 VGGGG++AG+A +K L P+ V EP ADD +S G + PP T ADGV++ Sbjct: 177 VGGGGLLAGLATAVKALSPTTLVLGVEPEAADDAKRSLEAGRILRLEAPPRTRADGVRTL 236 Query: 243 SIGLNTWPIIRDLVDDVFTVTEDEIKYATQLVWERMKLLIEPTAGVGLAAVLSQHFQTVS 302 S+G T+PI+R+ VD + TV+E+ + A +L++ R K ++EPT + LAAVL + Sbjct: 237 SLGERTFPILRERVDGILTVSEEALLEAERLLFTRTKQVVEPTGALPLAAVLEHGARLP- 295 Query: 303 PEVKNICIVLSGGNVDLT 320 + + ++LSGGN D + Sbjct: 296 ---QTLALLLSGGNRDFS 310 >3FCA-A nrPDB Length = 291 Score = 245 bits (626), Expect = 1e-65, Method: Composition-based stats. Identities = 71/309 (22%), Positives = 130/309 (42%), Gaps = 24/309 (7%) Query: 19 IQDSVHLTPVLTSSILNQIAGRNLFFKCELFQKTGSFKIRGALNAIRGLIPDTLEGKPKA 78 ++ + TP++ ++ + K E GS K R AL I L Sbjct: 2 MERLIGSTPIVRLDSID----SRIALKLEKNNPGGSVKDRPALFMILDAEKRGLLKN--G 55 Query: 79 VVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPNCKKLAIQAYGASIVYSEPSDESRENV 138 +V +SGN G A+ G + +P+T ++ ++ GA +V + + V Sbjct: 56 IVEPTSGNMGIAIAMIGAKRGHRVILTMPETMSVERRKVLKMLGAELVLTPGELGMKGAV 115 Query: 139 --AQRIIQETEGILVHPNQEPA-VIAGQGTIALEVLNQVP-LVDALVVPVGGGGMVAGIA 194 A I +ET +++ + P V + Q T E+L Q+ +DA V VG GG ++G+ Sbjct: 116 EKALEISRETGAHMLNQFENPYNVYSHQFTTGPEILKQMDYQIDAFVAGVGTGGTISGVG 175 Query: 195 ITIKTLKPS-VKVYAAEPSNADDCYQSKLKGELTPNLHPPETIADGVKSSIGLNTWPIIR 253 +K + VK+ A EP+ + P H + I G I + R Sbjct: 176 RVLKGFFGNGVKIVAVEPAKSPVLSGG------QPGKHAIQGIGAGFVPKI------LDR 223 Query: 254 DLVDDVFTVTEDEIKYATQLVWERMKLLIEPTAGVGLAAVLSQHFQTVSPEVKNICIVLS 313 ++D+V TV ++E + + ++ LL+ ++G +AA L Q + P+ + + + Sbjct: 224 SVIDEVITVEDEEAYEMARYLAKKEGLLVGISSGANVAAALK-VAQKLGPDARVVTVAPD 282 Query: 314 GGNVDLTSL 322 L+ L Sbjct: 283 HAERYLSIL 291 >5C3U-A nrPDB Length = 366 Score = 241 bits (614), Expect = 5e-64, Method: Composition-based stats. Identities = 81/335 (24%), Positives = 149/335 (44%), Gaps = 24/335 (7%) Query: 9 FADVEKAHLNIQDSVHLTPVLTSSILNQIAGRNLFFKCELFQKTGSFKIRGALNAIRGLI 68 F D++ H+ TP+L + L + N+F K E Q +GS K+RG I Sbjct: 12 FDDLQSLHV-------ATPLLHAPNLTKELECNVFLKMENIQPSGSVKMRG----IGAFC 60 Query: 69 PDTLE--GKPKAVVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPNCKKLAIQAYGASIV 126 ++ G V S N A++Y A+ G+ A IVVP+ +I+ G+ ++ Sbjct: 61 YQAVQTRGTNIQFVCGSGPNTVLAVSYCARQLGVEAIIVVPKATNERICQSIRTDGSHLI 120 Query: 127 YSEPSDESRENVAQRIIQETEGILVHPNQEPAVIAGQGTIALEV---LNQVPLVDALVVP 183 + + E A+++++ GI V + + G TI E+ LN P A++ P Sbjct: 121 LYGENWTAAEVHARKLVRRN-GIYVPSSDHALIWQGHSTIVQELKTQLNDNPPA-AIICP 178 Query: 184 VGGGGMVAGIAITIKTL-KPSVKVYAAEPSNADDCYQSKLKGELTPNLHPPETIADGVKS 242 VGGGG++ G+ + ++ V V A E ++ S + GEL + Sbjct: 179 VGGGGLLNGVIMGLQEADWKDVPVIAVETHGSNAFQASVVAGELVIMEKNNTIATSLISK 238 Query: 243 SIGLNTWPIIRDLVDDVFTVTEDEIKYATQLVWERMKLLIEPTAGVGLAAVLSQHFQTVS 302 ++ + + + F V++ A +L E K+L+E +AG L+ + + + Sbjct: 239 AVSSKSLELSLNHPVVPFAVSDAMAADAVRLFAEDFKMLVEASAGAALSLCYTHLIRDIL 298 Query: 303 PE---VKNICIVLSGG-NVDLTSLS-WVKQAERPA 332 P K++ ++++GG ++ L L + K+ PA Sbjct: 299 PSLSPAKDVVVLVTGGSDISLAHLDEYRKKYMHPA 333 >4LMA-A nrPDB Length = 326 Score = 238 bits (607), Expect = 3e-63, Method: Composition-based stats. Identities = 85/328 (25%), Positives = 140/328 (42%), Gaps = 23/328 (7%) Query: 12 VEKAHLNIQDSVHLTPVLTSSILNQIAGR--NLFFKCELFQKTGSFKIRGALNAIRGLIP 69 + AH + + V TP++ + + Q G + K E S K R + I Sbjct: 8 MRIAHD-VTELVGRTPLVQLNRIPQAEGCLGRIVMKLEGMNPAASVKDRIGTHMINSAEK 66 Query: 70 DTLEGKPKAV-VTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPNCKKLAIQAYGASIVYS 128 L V V +SGN G AL A +G + +P+T ++ ++AYGA++ + Sbjct: 67 AGLINPETTVLVEPTSGNTGIALAMTAAAKGYRLILTMPETMSLERRAMLKAYGATLELT 126 Query: 129 EPSDESRENV--AQRIIQETEGIL-VHPNQEPAVIA-GQGTIALEVLNQV-PLVDALVVP 183 S + + AQ+I+ G + + P+ + T A E+ VD +V Sbjct: 127 PGSQGMKGAILRAQQIVDSIPGAYMLQQFRNPSNPEIHRLTTAEEIWQDTEGQVDFIVAG 186 Query: 184 VGGGGMVAGIAITIKTLKPSVKVYAAEPSNADDCYQSKLKGELTPNLHPPETIADGVKSS 243 VG GG + G+A IK+ KPS +V A EP N+ P H + I G Sbjct: 187 VGTGGTITGVAEVIKSRKPSFQVVAVEPFNSPVISGG------NPGPHKIQGIGAGFIPE 240 Query: 244 IGLNTWPIIRDLVDDVFTVTEDEIKYATQLVWERMKLLIEPTAGVGLAAVLSQHFQTVSP 303 + + DL+D+V TV+++E + + + LL ++G L A + Q Q Sbjct: 241 V------LRTDLIDEVITVSDEEAFQFGRRLAKEEGLLSGISSGANLCAAI-QLAQRPEN 293 Query: 304 EVKNICIV-LSGGNVDLTSLSWVKQAER 330 E K I ++ S G L++L + ER Sbjct: 294 EGKLIVVIQPSFGERYLSTLMFQNIEER 321 >3PC3-A nrPDB Length = 527 Score = 234 bits (597), Expect = 4e-62, Method: Composition-based stats. Identities = 73/310 (23%), Positives = 125/310 (40%), Gaps = 24/310 (7%) Query: 18 NIQDSVHLTPVLTSSIL--NQIAGRNLFFKCELFQKTGSFKIRGALNAIRGLIPDTLEGK 75 NI + + TP++ + + + ++ KCE GS K R ++ L Sbjct: 53 NILEVIGCTPLVKLNNIPASDGIECEMYAKCEFLNPGGSVKDRIGYRMVQDAEEQGLLKP 112 Query: 76 PKAVVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPNCKKLAIQAYGASIVYSE-----P 130 ++ +SGN G L A ++G IV+P+ N K A++ GA I+ + Sbjct: 113 GYTIIEPTSGNTGIGLAMACAVKGYKCIIVMPEKMSNEKVSALRTLGAKIIRTPTEAAYD 172 Query: 131 SDESRENVAQRIIQETEG-ILVHPNQEPAV-IAGQGTIALEVLNQVP-LVDALVVPVGGG 187 S E VAQ++ +ET I++ + +A A E+L Q+ VD +VV G Sbjct: 173 SPEGLIYVAQQLQRETPNSIVLDQYRNAGNPLAHYDGTAAEILWQLDNKVDMIVVSAGTA 232 Query: 188 GMVAGIAITIKTLKPSVKVYAAEPSNADDCYQSKLKGELTPNLHPPETIADGVKSSIGLN 247 G ++GI IK PS ++ +P + P + IG + Sbjct: 233 GTISGIGRKIKEQVPSCQIVGVDPYGSILAR---------PAELNKTDVQFYEVEGIGYD 283 Query: 248 TWP-IIRDLVDDVFTV--TEDEIKYATQLVWERMKLLIEPTAGVGLAAVLSQHFQTVSPE 304 P + D V DV+T D + +L E L + G AA+ +H + + Sbjct: 284 FPPTVFDDTVVDVWTKIGDSDCFPMSRRLNAEEGLLCGGSSGGAMHAAL--EHARKLKKG 341 Query: 305 VKNICIVLSG 314 + + I+ G Sbjct: 342 QRCVVILPDG 351 >6C2H-A nrPDB Length = 375 Score = 234 bits (596), Expect = 4e-62, Method: Composition-based stats. Identities = 66/312 (21%), Positives = 121/312 (38%), Gaps = 28/312 (8%) Query: 18 NIQDSVHLTPVLTSSILNQIAGR--NLFFKCELFQKTGSFKIRGALNAIRGLIPDTLEGK 75 N+ D V TP++ L + G ++ K EL+ GS K R A + + Sbjct: 35 NVIDLVGNTPLIALKKLPKALGIKPQIYAKLELYNPGGSIKDRIAKSMVEEAEASGRIHP 94 Query: 76 -PKAVVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPNCKKLAIQAYGASIVYSE----- 129 ++ +SGN G L ++G I +P+ N K ++A GA I+ + Sbjct: 95 SRSTLIEPTSGNTGIGLALIGAIKGYRTIITLPEKMSNEKVSVLKALGAEIIRTPTAAAW 154 Query: 130 PSDESRENVAQRIIQETEGI--------LVHPNQEPAVIAGQGTIALEVLNQVPLVDALV 181 S ES VA+++ +E G +++P + LE LN + A+V Sbjct: 155 DSPESHIGVAKKLEKEIPGAVILDQYNNMMNPEAHYFGTGREIQRQLEDLNLFDNLRAVV 214 Query: 182 VPVGGGGMVAGIAITIKTLKPSVKVYAAEPSNADDCYQSKLKGELTPNLHPPETIADGVK 241 G GG ++GI+ +K +++ A+P + P I D Sbjct: 215 AGAGTGGTISGISKYLKEQNDKIQIVGADPFGSILA---------QPENLNKTDITDYKV 265 Query: 242 SSIGLNTWPII--RDLVDDVFTVTEDEIKYATQLVWERMKLLIEPTAGVGLAAVLSQHFQ 299 IG + P + R L+D + + + + +L+ ++G AV+ + + Sbjct: 266 EGIGYDFVPQVLDRKLIDVWYKTDDKPSFKYARQLISNEGVLVGGSSGSAFTAVVK-YCE 324 Query: 300 TVSPEVKNICIV 311 ++ IV Sbjct: 325 DHPELTEDDVIV 336 >2BHS-A nrPDB Length = 303 Score = 233 bits (593), Expect = 1e-61, Method: Composition-based stats. Identities = 58/307 (18%), Positives = 115/307 (37%), Gaps = 25/307 (8%) Query: 19 IQDSVHLTPVLTSSILNQIAGRNLFFKCELFQKTGSFKIRGALNAIRGLIPDTLEGKPKA 78 ++ ++ TP++ + G ++ K E GS K R AL+ I Sbjct: 4 LEQTIGNTPLVKLQRMGPDNGSEVWLKLEGNNPAGSVKDRAALSMIVEAEKRGEIKPGDV 63 Query: 79 VVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPNCKKLAIQAYGASIVYS--EPSDESRE 136 ++ +SGN G AL A L+G +++P ++ A++AYGA ++ E E Sbjct: 64 LIEATSGNTGIALAMIAALKGYRMKLLMPDNMSQERRAAMRAYGAELILVTKEQGMEGAR 123 Query: 137 NVAQRIIQETEGILVHPNQEPAV-IAGQGTIALEVLNQV-PLVDALVVPVGGGGMVAGIA 194 ++A + EG L+ P A T E+ Q + V +G G + G++ Sbjct: 124 DLALEMANRGEGKLLDQFNNPDNPYAHYTTTGPEIWQQTGGRITHFVSSMGTTGTITGVS 183 Query: 195 ITIKTLKPSVKVYAAEPSNADDCYQSKLKGELTPNLHPPETIADGVKSSIGLNTWPIIRD 254 ++ V + +P + P + P Sbjct: 184 RFMREQSKPVTIVGLQPEEGSSIPGIRR----WPTEYLPGIFNAS--------------- 224 Query: 255 LVDDVFTVTEDEIKYATQLVWERMKLLIEPTAGVGLAAVLSQHFQTVSPEVKNICIVLSG 314 LVD+V + + + + + + R + ++G +A L +P+ + I+ Sbjct: 225 LVDEVLDIHQRDAENTMRELAVREGIFCGVSSGGAVAGAL--RVAKANPDAVVVAIICDR 282 Query: 315 GNVDLTS 321 G+ L++ Sbjct: 283 GDRYLST 289 >1PWH-A nrPDB Length = 327 Score = 231 bits (590), Expect = 3e-61, Method: Composition-based stats. Identities = 85/319 (26%), Positives = 148/319 (46%), Gaps = 17/319 (5%) Query: 20 QDSVH-LTPVLTSSILNQIAGRNLFFKCELFQKTGSFKIRGALNAIRGLIPDTLEGKPKA 78 Q+S+H TP+ S L+++AG ++F K + Q +GSFKIRG I L + K Sbjct: 4 QESLHVKTPLRDSMALSKVAGTSVFLKMDSSQPSGSFKIRG----IGHLCKMKAKQGCKH 59 Query: 79 VVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPNCKKLAIQAYGASIVYSEPSDESRENV 138 V S+GN G A YAA+ G+PA IVVP T P ++ GA++ + + Sbjct: 60 FVCSSAGNAGMATAYAARRLGLPATIVVPSTTPALTIERLKNEGATVEVVGEMLDEAIQL 119 Query: 139 AQRIIQETE-GILVHPNQEPAVIAGQGTIALEVLNQVP-LVDALVVPVGGGGMVAGIAIT 196 A+ + + + + P +P + G ++ E+ + A+V+ VGGGG++ G+ Sbjct: 120 AKALEKNNPGWVYISPFDDPLIWEGHTSLVKELKETLSAKPGAIVLSVGGGGLLCGVVQG 179 Query: 197 IKT-LKPSVKVYAAEPSNADDCYQSKLKGELTPNLHPPETIADGV-KSSIGLNTWPIIRD 254 ++ V + A E A + + +G+L L ++A + +++G T + + Sbjct: 180 LREVGWEDVPIIAMETFGAHSFHAAVKEGKLV-TLPKITSVAKALGVNTVGAQTLKLFYE 238 Query: 255 LVDDVFTVTEDEIKYATQLVWERMKLLIEPTAGVGLAAVLS-------QHFQTVSPEVKN 307 +++ E A + + K+L+EP G LAAV S + +P Sbjct: 239 HPIFSEVISDQEAVTAIEKFVDDEKILVEPACGAALAAVYSGVVCRLQAEARLQTPLASL 298 Query: 308 ICIVLSGGNVDLTSLSWVK 326 + IV G N+ L L +K Sbjct: 299 VVIVCGGSNISLAQLQALK 317 >2Q3D-A nrPDB Length = 313 Score = 230 bits (587), Expect = 5e-61, Method: Composition-based stats. Identities = 74/311 (23%), Positives = 129/311 (41%), Gaps = 19/311 (6%) Query: 17 LNIQDSVHLTPVLTSSILNQIAGRNLFFKCELFQKTGSFKIRGALNAIRGLIPDTLEGKP 76 +I + TP++ + A ++ K E F S K R + ++ L Sbjct: 8 EDITQLIGRTPLVRLRRVTDGAVADIVAKLEFFNPANSVKDRIGVAMLQAAEQAGLIKPD 67 Query: 77 KAVVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPNCKKLAIQAYGASIVYSEPSDESRE 136 ++ +SGN G AL G + +P+T +++ ++AYGA ++ + +D Sbjct: 68 TIILEPTSGNTGIALAMVCAARGYRCVLTMPETMSLERRMLLRAYGAELILTPGADGMSG 127 Query: 137 NVAQ--RIIQETEGILVH-PNQEPAVIA-GQGTIALEVLNQVP-LVDALVVPVGGGGMVA 191 +A+ + + + V + PA A + T A EV VD +V VG GG + Sbjct: 128 AIAKAEELAKTDQRYFVPQQFENPANPAIHRVTTAEEVWRDTDGKVDIVVAGVGTGGTIT 187 Query: 192 GIAITIKTLKPSVKVYAAEPSNADDCYQSKLKGELTPNLHPPETIADGVKSSIGLNTWPI 251 G+A IK KPS + A EP+ S + HP + I G + + Sbjct: 188 GVAQVIKERKPSARFVAVEPA------ASPVLSGGQKGPHPIQGIGAGFVPPV------L 235 Query: 252 IRDLVDDVFTVTEDEIKYATQLVWERMKLLIEPTAGVGLAAVLSQHFQTVSPEVKNICIV 311 +DLVD++ TV ++ + + LL+ ++G A L Q + K I +V Sbjct: 236 DQDLVDEIITVGNEDALNVARRLAREEGLLVGISSGAATVAAL-QVARRPENAGKLIVVV 294 Query: 312 LSG-GNVDLTS 321 L G L++ Sbjct: 295 LPDFGERYLST 305 >2JC3-A nrPDB Length = 303 Score = 230 bits (587), Expect = 5e-61, Method: Composition-based stats. Identities = 58/307 (18%), Positives = 117/307 (38%), Gaps = 25/307 (8%) Query: 19 IQDSVHLTPVLTSSILNQIAGRNLFFKCELFQKTGSFKIRGALNAIRGLIPDTLEGKPKA 78 ++ ++ TP++ + G ++ K E GS K R AL+ I Sbjct: 4 LEQTIGNTPLVKLQRIGPDNGSEIWVKLEGNNPAGSVKDRAALSMIVEAEKRGEIKPGDV 63 Query: 79 VVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPNCKKLAIQAYGASIVYS--EPSDESRE 136 ++ +SGN G AL A L+G +++P ++ A++AYGA ++ E E Sbjct: 64 LIEATSGNTGIALAMIAALKGYRMKLLMPDNMSQERRAAMRAYGAELILVTKEQGMEGAR 123 Query: 137 NVAQRIIQETEGILVHPNQEPAV-IAGQGTIALEVLNQV-PLVDALVVPVGGGGMVAGIA 194 ++A + + EG L+ P A T E+ Q + V +G G + G++ Sbjct: 124 DLALAMSERGEGKLLDQFNNPDNPYAHYTTTGPEIWRQTSGRITHFVSSMGTTGTITGVS 183 Query: 195 ITIKTLKPSVKVYAAEPSNADDCYQSKLKGELTPNLHPPETIADGVKSSIGLNTWPIIRD 254 ++ + V + +P + P + P Sbjct: 184 RFLREQEKPVTIVGLQPEEGSSIPGIRR----WPAEYMPGIFNAS--------------- 224 Query: 255 LVDDVFTVTEDEIKYATQLVWERMKLLIEPTAGVGLAAVLSQHFQTVSPEVKNICIVLSG 314 LVD+V + +++ + + + R + ++G +A L +P + I+ Sbjct: 225 LVDEVLDIHQNDAENTMRELAVREGIFCGVSSGGAVAGAL--RVARATPGAIVVAIICDR 282 Query: 315 GNVDLTS 321 G+ L++ Sbjct: 283 GDRYLST 289 >2EFY-A nrPDB Length = 304 Score = 230 bits (587), Expect = 6e-61, Method: Composition-based stats. Identities = 74/312 (23%), Positives = 125/312 (40%), Gaps = 21/312 (6%) Query: 17 LNIQDSVHLTPVLTSSILNQIAGRNLFFKCELFQKTGSFKIRGALNAIRGLIPDTLEGKP 76 + ++ ++ TPV+ + + + ++ K E GS K R A I+ + Sbjct: 1 MRVEGAIGKTPVVRLAKVVEPDMAEVWVKLEGLNPGGSIKDRPAWYMIKDAEERGILRPG 60 Query: 77 KA--VVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPNCKKLAIQAYGASIVYSEPSDES 134 +V +SGN G L A G + +P +K ++A+GA +V ++P Sbjct: 61 SGQVIVEPTSGNTGIGLAMIAASRGYRLILTMPAQMSEERKRVLKAFGAELVLTDPERRM 120 Query: 135 --RENVAQRIIQETEGILVHPNQEPAVI-AGQGTIALEVLNQV-PLVDALVVPVGGGGMV 190 A R+ +E + + PA + A T E+ + +DA V G GG + Sbjct: 121 LAAREEALRLKEELGAFMPDQFKNPANVRAHYETTGPELYEALEGRIDAFVYGSGTGGTI 180 Query: 191 AGIAITIKTLKPSVKVYAAEPSNADDCYQSKLKGELTPNLHPPETIADGVKSSIGLNTWP 250 G+ +K P VKV A EP+ ++ K G+ P I + + S Sbjct: 181 TGVGRYLKERIPHVKVIAVEPARSNVLSGGK-MGQHGFQGMGPGFIPENLDLS------- 232 Query: 251 IIRDLVDDVFTV-TEDEIKYATQLVWERMKLLIEPTAGVGLAAVLSQHFQTVSPEVKNIC 309 L+D V V ED A +L E L + G+ AA+ Q + + P + C Sbjct: 233 ----LLDGVIQVWEEDAFPLARRLAREEGLFLGMSSGGIVWAAL--QVARELGPGKRVAC 286 Query: 310 IVLSGGNVDLTS 321 I GG L++ Sbjct: 287 ISPDGGWKYLST 298 >5JJC-A nrPDB Length = 342 Score = 228 bits (580), Expect = 3e-60, Method: Composition-based stats. Identities = 73/320 (22%), Positives = 129/320 (40%), Gaps = 21/320 (6%) Query: 16 HLNIQDSVHLTPVLTSSILNQIAGRNLFFKCELFQKTGSFKIRGALNAIRGLIPDTLEGK 75 ++ D++ TP++ S +++ G +++ K E S K R AL IR L Sbjct: 2 FNSVLDTIGNTPLIRLSKASELTGCDIYGKAEFLNPGQSVKDRAALYIIRDAEKRGLLRP 61 Query: 76 PKAVVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPNCKKLAIQAYGASIV------YSE 129 +V ++GN G LT AK G IV+P+TA KK A++ GA ++ Y Sbjct: 62 GGVIVEGTAGNTGIGLTMVAKALGYRTAIVIPETASQEKKDALRLLGAELIEVPAAPYRN 121 Query: 130 PSDESR--ENVAQRIIQE--TEGILVHPNQEPAVIAGQ-GTIALEVLNQV-PLVDALVVP 183 P++ R +A+++ + I + T A E+ +D V Sbjct: 122 PNNAVRLSGRLAEQLAKTEPNGAIWANQFDNTVNRQAHIETTAQEIWRDTSDQIDGFVAA 181 Query: 184 VGGGGMVAGIAITIKTLKPSVKVYAAEPSNADDCYQSKLKGELTPNLHPP-ETIADGVKS 242 VG GG +AG AI +K ++K+ A+P A + GEL E I G + Sbjct: 182 VGSGGTLAGTAIGLKERNHNIKIALADPHGA-ALHAFYTTGELKAEGDSITEGIGQGRIT 240 Query: 243 SIGLNTWPIIRDLVDDVFTVTEDEIKYATQLVWERMKLLIEPTAGVGLAAVLSQHFQTVS 302 + P + + + E + E L + ++G+ +A + + + Sbjct: 241 ANLEGFTPDFS------YQIPDAEALDILFALVEEEGLCLGGSSGINIAGAIR-LAKDLG 293 Query: 303 PEVKNICIVLSGGNVDLTSL 322 P + ++ GN + L Sbjct: 294 PGHTIVTVLCDYGNRYQSKL 313 >6AHI-A nrPDB Length = 314 Score = 227 bits (579), Expect = 4e-60, Method: Composition-based stats. Identities = 61/312 (19%), Positives = 122/312 (39%), Gaps = 25/312 (8%) Query: 19 IQDSVHLTPVLTSSILNQIAGRN--LFFKCELFQKTGSFKIRGALNAIRGLIPDTLEGKP 76 +QD++ TPV + + N ++ K E GS K R I Sbjct: 7 MQDAIGRTPVFKFTNKDYPIPLNSAIYAKLEHLNPGGSVKDRLGQYLIGEGFKTGKITSK 66 Query: 77 KAVVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPNCKKLAIQAYGASIVYSEPSDE--S 134 ++ ++GN G AL A + VVP+ K+ ++A GA ++ + S+ Sbjct: 67 TTIIEPTAGNTGIALALVAIKHHLKTIFVVPEKFSTEKQQIMRALGALVINTPTSEGISG 126 Query: 135 RENVAQRIIQETEGILVH-PNQEPAVI-AGQGTIALEVLNQVP-LVDALVVPVGGGGMVA 191 ++ + + + + P A T+A E++ ++ + + V +G GG A Sbjct: 127 AIKKSKELAESIPDSYLPLQFENPDNPAAYYHTLAPEIVQELGTNLTSFVAGIGSGGTFA 186 Query: 192 GIAITIKTLKPSVKVYAAEPSNADDCYQSKLKGELTPNLHPPETIADGVKSSIGLNTWPI 251 G A +K P++++ EP + + P H E I G+ P Sbjct: 187 GTARYLKERIPAIRLIGVEPEGS-------ILNGGEPGPHEIEGI--------GVEFIPP 231 Query: 252 IRDL--VDDVFTVTEDEIKYATQLVWERMKLLIEPTAGVGLAAVLSQHFQTVSPEVKNIC 309 + +D T++++E T+ + ++ LL+ ++G A L + Q + + + Sbjct: 232 FFENLDIDGFETISDEEGFSYTRKLAKKNGLLVGSSSGAAFVAALKE-AQRLPEGSQVLT 290 Query: 310 IVLSGGNVDLTS 321 I + L+ Sbjct: 291 IFPDVADRYLSK 302 >4H27-A nrPDB Length = 364 Score = 225 bits (574), Expect = 2e-59, Method: Composition-based stats. Identities = 81/315 (25%), Positives = 141/315 (44%), Gaps = 16/315 (5%) Query: 25 LTPVLTSSILNQIAGRNLFFKCELFQKTGSFKIRGALNAIRGLIPDTLEGKPKAVVTHSS 84 TP+ S L+++AG +++ K + Q +GSFKIRG I + V SS Sbjct: 46 KTPIRDSMALSKMAGTSVYLKMDSAQPSGSFKIRG----IGHFCKRWAKQGCAHFVCSSS 101 Query: 85 GNHGQALTYAAKLEGIPAYIVVPQTAPNCKKLAIQAYGASIVYSEPSDESRENVAQRIIQ 144 GN G A YAA+ G+PA IVVP T P ++ GA++ + +A+ + + Sbjct: 102 GNAGMAAAYAARQLGVPATIVVPGTTPALTIERLKNEGATVKVVGELLDEAFELAKALAK 161 Query: 145 ETE-GILVHPNQEPAVIAGQGTIALEVLNQV-PLVDALVVPVGGGGMVAGIAITIKT-LK 201 + + P +P + G +I E+ + A+ + VGGGG++ G+ ++ Sbjct: 162 NNPGWVYIPPFDDPLIWEGHASIVKELKETLWEKPGAIALSVGGGGLLCGVVQGLQEVGW 221 Query: 202 PSVKVYAAEPSNADDCYQSKLKGELTPNLHPPETIADGV-KSSIGLNTWPIIRDLVDDVF 260 V V A E A + + G+L +L ++A + ++G + ++ Sbjct: 222 GDVPVIAMETFGAHSFHAATTAGKLV-SLPKITSVAKALGVKTVGAQALKLFQEHPIFSE 280 Query: 261 TVTEDEIKYATQLVWERMKLLIEPTAGVGLAAVLSQHFQTV-------SPEVKNICIVLS 313 +++ E A + + K+L+EP G LAAV S Q + +P + IV Sbjct: 281 VISDQEAVAAIEKFVDDEKILVEPACGAALAAVYSHVIQKLQLEGNLRTPLPSLVVIVCG 340 Query: 314 GGNVDLTSLSWVKQA 328 G N+ L L +K+ Sbjct: 341 GSNISLAQLRALKEQ 355 >4OFX-A nrPDB Length = 319 Score = 223 bits (568), Expect = 8e-59, Method: Composition-based stats. Identities = 68/317 (21%), Positives = 127/317 (40%), Gaps = 29/317 (9%) Query: 17 LNIQDSVHLTPVLTSSILNQIAGRNLFFKCELFQKTGSFKIRGALNAIRGLIPDTLEGKP 76 NI + TPV+ + Q L+ KCE GS K R I Sbjct: 7 DNILQVIGKTPVVRLHRIGQSLPCELYGKCEFLNPGGSVKDRIGAAMIESAEKQGKIKPG 66 Query: 77 KAVVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPNCKKLAIQAYGASIVYSEPS----- 131 ++ +SGN G + A ++G I +P+ + K++ ++A GA+I + Sbjct: 67 DTLIEPTSGNTGIGIALAGAVKGYRVIITMPEKMSHEKQVVLEALGATIYRTPTEAAYDD 126 Query: 132 DESRENVAQRIIQETEGILV----HPNQEPAVIAGQGTIALEVLNQVPL-VDALVVPVGG 186 ES ++A+R+ QE + + P + T E+L+ + + +V+ VG Sbjct: 127 PESHISLAKRLNQEIPNSYILDQYSNAENPDI--HYQTTGQEILDDMGENLSMVVMGVGT 184 Query: 187 GGMVAGIAITIKTLKPSVKVYAAEPSNADDCYQSKLKGELTPNLHPPETIADGVKSSIGL 246 GG + G+A +K + PS+++ +P S L G + I + IG Sbjct: 185 GGTIIGVAKKLKEVNPSIQIIGVDPIG------SILGGG--------DEIKPYLVEGIGY 230 Query: 247 NTWPIIRD--LVDDVFTVTEDEIKYATQLVWERMKLLIEPTAGVGLAAVLSQHFQTVSPE 304 + P + D L+D+ + + + + + LL+ ++G + A Q Q + Sbjct: 231 DFIPEVLDNNLIDEYIKINDKDSFLMARRLIREEGLLVGGSSGSAVWAA-CQAAQRLKEG 289 Query: 305 VKNICIVLSGGNVDLTS 321 + + I+ LT Sbjct: 290 ERCLVILPDAIRNYLTK 306 >2PQM-A nrPDB Length = 343 Score = 219 bits (558), Expect = 1e-57, Method: Composition-based stats. Identities = 70/326 (21%), Positives = 132/326 (40%), Gaps = 21/326 (6%) Query: 13 EKAHLNIQDSVHLTPVLTSSILNQIA----GRNLFFKCELFQKTGSFKIRGALNAIRGLI 68 ++ + NI +++ TP++ + + G + K E F S K R N + I Sbjct: 11 KRIYHNILETIGGTPLVELHGVTEHPRIKKGTRILVKLEYFNPMSSVKDRVGFNIVYQAI 70 Query: 69 PDTLEGKPKAVVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPNCKKLAIQAYGASIVYS 128 D ++ +SGN G AL A + G I +P T +++ ++A+GA ++ + Sbjct: 71 KDGRLKPGMEIIESTSGNTGIALCQAGAVFGYRVNIAMPSTMSVERQMIMKAFGAELILT 130 Query: 129 EPSDESRENVAQ--RIIQETEGILV--HPNQEPAVIAGQGTIALEVLNQVP-LVDALVVP 183 E + + ++I+E G + P A A E+ VD +V Sbjct: 131 EGKKGMPGAIEEVNKMIKENPGKYFVANQFGNPDNTAAHHYTANEIWEDTDGEVDIVVSA 190 Query: 184 VGGGGMVAGIAITIKTLKPSVKVYAAEPSNADDCYQSKLKGELTPNLHPPETIADGVKSS 243 VG G V G+A +K K +K+ A EP + + K KG H + I G Sbjct: 191 VGTSGTVIGVAEKLKEKKKGIKIIAVEPEES-AVLEGKAKG-----PHGIQGIGAGFIPD 244 Query: 244 IGLNTWPIIRDLVDDVFTVTEDEIKYATQLVWERMKLLIEPTAGVGLAAVLSQHFQTVSP 303 I ++ VD++ + + + V + ++ ++G + A L + + + Sbjct: 245 I------YKKEFVDEIIPIKTQDAWKMARAVVKYDGIMCGMSSGAAILAGLKEAEKPENE 298 Query: 304 EVKNICIVLSGGNVDLTSLSWVKQAE 329 + IV S G L++ + + E Sbjct: 299 GKTIVIIVPSCGERYLSTDLYKIKDE 324 >4I1Y-A nrPDB Length = 314 Score = 219 bits (557), Expect = 1e-57, Method: Composition-based stats. Identities = 70/318 (22%), Positives = 125/318 (39%), Gaps = 17/318 (5%) Query: 17 LNIQDSVHLTPVLTSSILNQIAGRNLFFKCELFQKTGSFKIRGALNAIRGLIPDTLEGKP 76 NI + TP++ + A ++ K E F GS K R + I L Sbjct: 9 ENIAQLIGGTPLVRLRRVTDGAAADVVAKLESFNPAGSIKDRIGVAMIDAAEKAGLIKPD 68 Query: 77 KAVVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPNCKKLAIQAYGASIVYSEPSDESRE 136 ++ +SGN G AL + G + +P T +++ ++AYGA +V + ++ Sbjct: 69 TIILEPTSGNTGIALAMVSAARGYKCVLTMPDTMSIERRMLLRAYGAELVLTPGAEGMAG 128 Query: 137 NVAQ--RIIQETEGILVH-PNQEPAVIA-GQGTIALEVLNQVP-LVDALVVPVGGGGMVA 191 +A+ + + + + + PA A T A EV VD V VG GG + Sbjct: 129 AIAKAEELAKTDDRYFIPQQFENPANPAVHAVTTAEEVWRDTDGKVDIFVSGVGTGGTIT 188 Query: 192 GIAITIKTLKPSVKVYAAEPSNADDCYQSKLKGELTPNLHPPETIADGVKSSIGLNTWPI 251 G+A IK +PS + A EP+ + HP + I G + + Sbjct: 189 GVAQVIKQRRPSAQFVAVEPAASPVLSGG------QKGPHPIQGIGAGFVPPV------L 236 Query: 252 IRDLVDDVFTVTEDEIKYATQLVWERMKLLIEPTAGVGLAAVLSQHFQTVSPEVKNICIV 311 LVD+V TV D+ + + LL ++G + A + + + ++ Sbjct: 237 DLALVDEVITVGNDDALELARRMATEEGLLFGISSGAAVWAARELAHRPENAGKLIVVVL 296 Query: 312 LSGGNVDLTSLSWVKQAE 329 G L+++ + +E Sbjct: 297 PDFGERYLSTVLFADLSE 314 >3VBE-A nrPDB Length = 344 Score = 215 bits (548), Expect = 2e-56, Method: Composition-based stats. Identities = 72/328 (21%), Positives = 140/328 (42%), Gaps = 23/328 (7%) Query: 16 HLNIQDSVHLTPVLTSSILNQIAGRNLFFKCELFQKTGSFKIRGALNAIRGLIPDTLEGK 75 ++ + TP++ + + + G + K E+ Q T S K R A I L Sbjct: 26 KKHVSQLIGRTPLVYLNKVTEGCGAYVAVKQEMMQPTASIKDRPAYAMITDAEEKNLITP 85 Query: 76 PKA-VVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPNCKKLAIQAYGASIVYSEPSDES 134 K ++ +SGN G ++ + A ++G + +P +++ ++A+GA ++ ++P+ Sbjct: 86 GKTTLIEPTSGNMGISMAFMAAMKGYKMVLTMPSYTSLERRVTMRAFGAELILTDPAKGM 145 Query: 135 RENV--AQRIIQETEGI-LVHPNQEPAVIA-GQGTIALEVLNQV-PLVDALVVPVGGGGM 189 V A +++ T ++ PA T E+ VD V+ +G GG Sbjct: 146 GGTVKKAYELLENTPNAHMLQQFSNPANTQVHFETTGPEIWEDTNGQVDIFVMGIGSGGT 205 Query: 190 VAGIAITIKTLKPSVKVYAAEPSNADDCYQSKLKGELTPNLHPPETIADGVKSSIGLNTW 249 V+G+ +K+ P+VK+Y EPS ++ K P H G K I Sbjct: 206 VSGVGQYLKSKNPNVKIYGVEPSESNVLNGGK------PGPHHITGNGVGFKPDI----- 254 Query: 250 PIIRDLVDDVFTVTEDEIKYATQLVWERMKLLIEPTAGVGLAAVLSQHFQTVSPEVKNIC 309 + D+++ V V+ ++ +++ + L++ ++G A L Q + K I Sbjct: 255 -LDLDVMEKVLEVSSEDAVNMARVLALKEGLMVGISSGANTVAALR-LAQLPENKGKLIV 312 Query: 310 IV-LSGGNVDLTSLSWV---KQAERPAP 333 V S G L+S+ + ++AE P Sbjct: 313 TVHPSFGERYLSSVLFQELRQEAENMQP 340 >4AEC-A nrPDB Length = 430 Score = 214 bits (546), Expect = 3e-56, Method: Composition-based stats. Identities = 63/319 (19%), Positives = 127/319 (39%), Gaps = 18/319 (5%) Query: 17 LNIQDSVHLTPVLTSSILNQIAGRNLFFKCELFQKTGSFKIRGALNAIRGLIPDTLEGKP 76 N+ + TP++ + + + N+ K E+ + S K R + + Sbjct: 115 DNVSQLIGKTPMVYLNSIAKGCVANIAAKLEIMEPCCSVKDRIGYSMVTDAEQKGFISPG 174 Query: 77 KAV-VTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPNCKKLAIQAYGASIVYSEPSDESR 135 K+V V +SGN G L + A G + +P + +++ ++A+GA +V ++P+ Sbjct: 175 KSVLVEPTSGNTGIGLAFIAASRGYRLILTMPASMSMERRVLLKAFGAELVLTDPAKGMT 234 Query: 136 ENV--AQRIIQETE-GILVHPNQEPAVIA-GQGTIALEVLNQV-PLVDALVVPVGGGGMV 190 V A+ I++ T ++ PA T E+ + VD V +G GG + Sbjct: 235 GAVQKAEEILKNTPDAYMLQQFDNPANPKIHYETTGPEIWDDTKGKVDIFVAGIGTGGTI 294 Query: 191 AGIAITIKTLKPSVKVYAAEPSNADDCYQSKLKGELTPNLHPPETIADGVKSSIGLNTWP 250 G+ IK P +V EP+ +D K P H + I G Sbjct: 295 TGVGRFIKEKNPKTQVIGVEPTESDILSGGK------PGPHKIQGIGAGFIPK------N 342 Query: 251 IIRDLVDDVFTVTEDEIKYATQLVWERMKLLIEPTAGVGLAAVLSQHFQTVSPEVKNICI 310 + + ++D+V ++ +E + + + L++ ++G AA + + + + Sbjct: 343 LDQKIMDEVIAISSEEAIETAKQLALKEGLMVGISSGAAAAAAIKVAKRPENAGKLIAVV 402 Query: 311 VLSGGNVDLTSLSWVKQAE 329 S G L++ + E Sbjct: 403 FPSFGERYLSTPLFQSIRE 421 >5XA2-A nrPDB Length = 309 Score = 214 bits (544), Expect = 5e-56, Method: Composition-based stats. Identities = 64/312 (20%), Positives = 116/312 (37%), Gaps = 17/312 (5%) Query: 20 QDSVHLTPVLTSSILNQIAGRNLFFKCELFQKTGSFKIRGALNAIRGLIPDTLEGKPKAV 79 +S+ TP++ + L + K E S K R I V Sbjct: 8 SESIGRTPLVQINRLTAGLSSRVLAKIEGRNPAYSVKCRIGAAMIWDAEQSGKLKPGMHV 67 Query: 80 VTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPNCKKLAIQAYGASIVYSEPSDESRENV- 138 V +SGN G AL + G + +P+T +++ ++++GA +V + +D + + Sbjct: 68 VEPTSGNTGIALAFVCAARGYKLTLTMPETMSIERRMMLKSFGADLVLTPGADGMKGAIS 127 Query: 139 -AQRIIQETEGILVHPNQEPAVIA-GQGTIALEVLNQV-PLVDALVVPVGGGGMVAGIAI 195 A+ + + + + PA A T E+ N VD V VG GG + G+A Sbjct: 128 KAEELAAQPGWFIPQQFKNPANPAIHVKTTGPEIWNDTEGQVDVFVAGVGTGGTITGVAR 187 Query: 196 TIK-TLKPSVKVYAAEPSNADDCYQSKLKGELTPNLHPPETIADGVKSSIGLNTWPIIRD 254 +K K V V A EP+ S + H + I G R Sbjct: 188 FLKHEKKHPVHVVAVEPA------ASPVLAGGPAGRHKIQGIGAGFVPDT------FDRS 235 Query: 255 LVDDVFTVTEDEIKYATQLVWERMKLLIEPTAGVGLAAVLSQHFQTVSPEVKNICIVLSG 314 +VD++ +VT+DE + + + + G +A L + + ++ Sbjct: 236 VVDEILSVTDDEAIETARKLAMEEGISCGISCGAAMAGALKVAARPEFAGKTIVTVLPDA 295 Query: 315 GNVDLTSLSWVK 326 G L++ + Sbjct: 296 GERYLSTALFEN 307 >2EGU-A nrPDB Length = 308 Score = 214 bits (544), Expect = 5e-56, Method: Composition-based stats. Identities = 71/314 (22%), Positives = 130/314 (41%), Gaps = 17/314 (5%) Query: 18 NIQDSVHLTPVLTSSILNQIAGRNLFFKCELFQKTGSFKIRGALNAIRGLIPDTLEGKPK 77 +I + + TP + + + +++ K E S K R AL I Sbjct: 7 SITELIGDTPAVKLNRIVDEDSADVYLKLEFMNPGSSVKDRIALAMIEAAEKAGKLKPGD 66 Query: 78 AVVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPNCKKLAIQAYGASIVYSEPSDESREN 137 +V +SGN G L A +G A +V+P T ++ ++AYGA +V + + R Sbjct: 67 TIVEPTSGNTGIGLAMVAAAKGYKAVLVMPDTMSLERRNLLRAYGAELVLTPGAQGMRGA 126 Query: 138 VAQ--RIIQETEGILVHPNQEPAVIA-GQGTIALEVLNQV-PLVDALVVPVGGGGMVAGI 193 +A+ +++E + + A + T E++ Q+ +DA V VG GG + G Sbjct: 127 IAKAEELVREHGYFMPQQFKNEANPEIHRLTTGKEIVEQMGDQLDAFVAGVGTGGTITGA 186 Query: 194 AITIKTLKPSVKVYAAEPSNADDCYQSKLKGELTPNLHPPETIADGVKSSIGLNTWPIIR 253 ++ P++K+YA EP+++ K P H + I G I + Sbjct: 187 GKVLREAYPNIKIYAVEPADSPVLSGGK------PGPHKIQGIGAGFVPDI------LDT 234 Query: 254 DLVDDVFTVTEDEIKYATQLVWERMKLLIEPTAGVGLAAVLSQHFQTVSPEVKNICIVLS 313 + D V TVT +E A + +L ++G + A L + + K + I+ S Sbjct: 235 SIYDGVITVTTEEAFAAARRAAREEGILGGISSGAAIHAALK-VAKELGKGKKVLAIIPS 293 Query: 314 GGNVDLTSLSWVKQ 327 G L++ + + Sbjct: 294 NGERYLSTPLYQFE 307 >2RKB-A nrPDB Length = 318 Score = 213 bits (541), Expect = 1e-55, Method: Composition-based stats. Identities = 83/324 (25%), Positives = 144/324 (44%), Gaps = 28/324 (8%) Query: 20 QDSVHL-TPVLTSSILNQIAGRNLFFKCELFQKTGSFKIRGALNAIRGLIPDTLEGKPKA 78 Q+ H+ TP+L S L+Q+AG +F KCE Q +GSFKIRG I + + + Sbjct: 1 QEPFHVVTPLLESWALSQVAGMPVFLKCENVQPSGSFKIRG----IGHFCQEMAKKGCRH 56 Query: 79 VVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPNCKKLAIQAYGASIVYSEPSDESRENV 138 +V S GN G A YAA+ GIPA IV+P++ +Q GA + + + Sbjct: 57 LVCSSGGNAGIAAAYAARKLGIPATIVLPESTSLQVVQRLQGEGAEVQLTGKVWDEANLR 116 Query: 139 AQRIIQETEGILVHPNQEPAVIAGQGTIALEV--LNQVPLVDALVVPVGGGGMVAGIAIT 196 AQ + + V P P + G ++ E+ + + P ++ GGG + +A Sbjct: 117 AQELAKRDGWENVPPFDHPLIWKGHASLVQELKAVLRTPPGALVLAVGGGGLLAGVVAGL 176 Query: 197 IKTLKPSVKVYAAEPSNADDCYQSKLKGELTPNLHPPETIAD-------GVKSSIGLNTW 249 ++ V + A E A + G+L L ++A ++ + Sbjct: 177 LEVGWQHVPIIAMETHGAHCFNAAITAGKLV-TLPDITSVAKSLGAKTVAARALECMQVC 235 Query: 250 PIIRDLVDDVFTVTEDEIKYATQLVWERMKLLIEPTAGVGLAAVLS------QHFQTVSP 303 I ++V+D V+ A Q + + ++L+EP G LAA+ S Q + P Sbjct: 236 KIHSEVVEDTEAVS------AVQQLLDDERMLVEPACGAALAAIYSGLLRRLQAEGCLPP 289 Query: 304 EVKNICIVLSGG-NVDLTSLSWVK 326 + ++ +++ GG N++ L +K Sbjct: 290 SLTSVVVIVCGGNNINSRELQALK 313 >5XW3-A nrPDB Length = 315 Score = 211 bits (538), Expect = 3e-55, Method: Composition-based stats. Identities = 57/313 (18%), Positives = 112/313 (35%), Gaps = 23/313 (7%) Query: 16 HLNIQDSVHLTPVLTSSILNQIAGRNLFFKCELFQKTGSFKIRGALNAIRGLIPDTLEGK 75 + + + + TP++ + + G LF K E + GS K R I + L + Sbjct: 4 YRGVHELIGHTPIVEITRFSLPEGVRLFAKLEFYNPGGSVKDRLGRELIEDALEKGLVTE 63 Query: 76 PKAVVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPNCKKLAIQAYGASIVYSEPSDESR 135 ++ ++GN G L AA + + VP+ K+ ++A GA++V++ Sbjct: 64 GGTIIEPTAGNTGIGLALAALQHDLRVIVCVPEKFSIEKQELMKALGATVVHTPTEQGMT 123 Query: 136 ENV--AQRIIQETEGILVHPN--QEPAVIAGQGTIALEVLNQV-PLVDALVVPVGGGGMV 190 + A+ ++ E E A T+ E+ + + ++ V G GG Sbjct: 124 GAIAKAKELVNEIPNSYSPSQFANEANPRAYFKTLGPELWSALNGEINIFVAGAGTGGTF 183 Query: 191 AGIAITIKTLKPSVKVYAAEPSNADDCYQSKLKGELTPNLHPPETIADGVKSSIGLNTWP 250 G A +K +K EP + G IGL P Sbjct: 184 MGTASYLKEKNIDIKTVIVEPEGS--ILNGGKAGSHETE-------------GIGLEFIP 228 Query: 251 IIRD--LVDDVFTVTEDEIKYATQLVWERMKLLIEPTAGVGLAAVLSQHFQTVSPEVKNI 308 D++ T+++ + + ++ LL+ ++G A L + + +P + Sbjct: 229 PFLKTSYFDEIHTISDRNAFLRVKELAQKEGLLVGSSSGAAFHASLLE-AEKAAPGTNIV 287 Query: 309 CIVLSGGNVDLTS 321 I L+ Sbjct: 288 TIFPDSSERYLSK 300 >6NMX-A nrPDB Length = 354 Score = 211 bits (537), Expect = 4e-55, Method: Composition-based stats. Identities = 77/303 (25%), Positives = 126/303 (41%), Gaps = 26/303 (8%) Query: 24 HLTPVLTSSILNQIAGRNLFFKCELFQKTGSFKIRGALNAIRGLIPDTLEGKPKAVVTHS 83 TP++ L++ G L K E TGSFK RG + A+ E ++ S Sbjct: 29 GNTPLIHLPKLSEQLGIELHVKTEGVNPTGSFKDRGMVMAV----AKAKEEGNDTIMCAS 84 Query: 84 SGNHGQALTYAAKLEGIPAYIVVPQTAPNCKKLAIQ-AYGASIVYSEPSDESRENVAQRI 142 +GN A A + +++P KLA YGA I+ + + + + + I Sbjct: 85 TGNTSAAAAAYAARANMKCIVIIPNGKIAFGKLAQAVMYGAEIIAIDGNFDDALKIVRSI 144 Query: 143 IQETEGILVHPNQEPAVIAGQGTIALEVLNQVPLV-DALVVPVGGGGMVAGIAITIKTLK 201 +++ LV+ + P + GQ T A EV Q+ D L +PVG G ++ K Sbjct: 145 CEKSPIALVN-SVNPYRLEGQKTAAFEVCEQLGEAPDVLAIPVGNAGNISAYWKGFKEYH 203 Query: 202 -------PSVKVYAAEPSNADDCYQSKLKGELTPNLHPPETIADGVK---SSIGLNTWPI 251 P ++ + AE S A ++ E+ N PETIA ++ + Sbjct: 204 EKNGTSLPKMRGFEAEGSAA------IVRNEVIEN---PETIATAIRIGNPASWDKAVKA 254 Query: 252 IRDLVDDVFTVTEDEIKYATQLVWERMKLLIEPTAGVGLAAVLSQHFQTVSPEVKNICIV 311 + + VT+DEI +A QL+ + EP + +A VL Q P+ + V Sbjct: 255 AEESNGKIDEVTDDEILHAYQLIAREEGVFAEPGSCASIAGVLKQVKSGEIPKGSKVVAV 314 Query: 312 LSG 314 L+G Sbjct: 315 LTG 317 >5J5V-A nrPDB Length = 323 Score = 206 bits (524), Expect = 1e-53, Method: Composition-based stats. Identities = 68/308 (22%), Positives = 123/308 (39%), Gaps = 17/308 (5%) Query: 22 SVHLTPVLTSSILNQIAGRNLFFKCELFQKTGSFKIRGALNAIRGLIPDTLEGKPKAVVT 81 ++ TP++ + + + K E + S K R N I + +V Sbjct: 11 TIGHTPLVRLNRIGN---GRILAKVESRNPSFSVKCRIGANMIWDAEKRGVLKPGVELVE 67 Query: 82 HSSGNHGQALTYAAKLEGIPAYIVVPQTAPNCKKLAIQAYGASIVYSEPSDESRENV--A 139 +SGN G AL Y A G + +P+T ++ ++A GA++V +E + + + A Sbjct: 68 PTSGNTGIALAYVAAARGYKLTLTMPETMSIERRKLLKALGANLVLTEGAKGMKGAIQKA 127 Query: 140 QRIIQETE--GILVHPNQEPAVIA-GQGTIALEVLNQVP-LVDALVVPVGGGGMVAGIAI 195 + I+ +L+ PA + T E+ VD + VG GG + G++ Sbjct: 128 EEIVASNPEKYLLLQQFSNPANPEIHEKTTGPEIWEDTDGQVDVFIAGVGTGGTLTGVSR 187 Query: 196 TIKTLKPSVKVY--AAEPSNADDCYQSKLKGELTPNLHPPETIADGVKSSIGLNTWPIIR 253 IK K + A EP+++ Q+ E+ P H + I G + + Sbjct: 188 YIKGTKGKTDLISVAVEPTDSPVIAQALAGEEIKPGPHKIQGIGAGFIPA------NLDL 241 Query: 254 DLVDDVFTVTEDEIKYATQLVWERMKLLIEPTAGVGLAAVLSQHFQTVSPEVKNICIVLS 313 LVD V +T +E + + E +L ++G +AA L + I+ S Sbjct: 242 KLVDKVIGITNEEAISTARRLMEEEGILAGISSGAAVAAALKLQEDESFTNKNIVVILPS 301 Query: 314 GGNVDLTS 321 G L++ Sbjct: 302 SGERYLST 309 >2ISQ-A nrPDB Length = 320 Score = 206 bits (523), Expect = 2e-53, Method: Composition-based stats. Identities = 66/322 (20%), Positives = 133/322 (41%), Gaps = 21/322 (6%) Query: 17 LNIQDSVHLTPVLTSSILNQIAGRNLFFKCELFQKTGSFKIRGALNAIRGLIPDTLEGKP 76 ++ + + TP++ + + + + K E+ + S K R + I L Sbjct: 5 KDVTELIGNTPLVYLNNVAEGCVGRVAAKLEMMEPCSSVKDRIGFSMISDAEKKGLIKPG 64 Query: 77 KAV-VTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPNCKKLAIQAYGASIVYSEPSDESR 135 ++V + +SGN G L + A +G I +P + +++ + A+G +V ++P+ + Sbjct: 65 ESVLIEPTSGNTGVGLAFTAAAKGYKLIITMPASMSTERRIILLAFGVELVLTDPAKGMK 124 Query: 136 ENVAQR---IIQETEGILVHPNQEPAVIA-GQGTIALEVLNQV-PLVDALVVPVGGGGMV 190 +A+ + + G ++ + PA T E+ +D V +G GG + Sbjct: 125 GAIAKAEEILAKTPNGYMLQQFENPANPKIHYETTGPEIWKGTGGKIDGFVSGIGTGGTI 184 Query: 191 AGIAITIKTLKPSVKVYAAEPSNADDCYQSKLKGELTPNLHPPETIADGVKSSIGLNTWP 250 G +K +VK+Y EP +S + P H + I G S+ Sbjct: 185 TGAGKYLKEQNANVKLYGVEP------VESAILSGGKPGPHKIQGIGAGFIPSVLN---- 234 Query: 251 IIRDLVDDVFTVTEDEIKYATQLVWERMKLLIEPTAGVGLAAVLSQHFQTVSPEVKNICI 310 DL+D+V V+ DE + + + LL+ ++G AA + + + + I Sbjct: 235 --VDLIDEVVQVSSDESIDMARQLALKEGLLVGISSGAAAAAAIKLAQRPENAGKLFVAI 292 Query: 311 VLSGGNVDLTSLSW---VKQAE 329 S G L+++ + K+AE Sbjct: 293 FPSFGERYLSTVLFDATRKEAE 314 >4LMB-A nrPDB Length = 322 Score = 203 bits (517), Expect = 7e-53, Method: Composition-based stats. Identities = 77/314 (24%), Positives = 129/314 (41%), Gaps = 22/314 (7%) Query: 17 LNIQDSVHLTPVLTSSILN--QIAGRNLFFKCELFQKTGSFKIRGALNAIRGLIPDTLEG 74 +I V TP++ + + + + K E S K R ++ + L Sbjct: 12 RDITQLVGRTPLVQLNRIPVAEGVKARIVVKLESMNPAASVKDRIGVSMVEDAEAAGLIH 71 Query: 75 KPKAV-VTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPNCKKLAIQAYGASIVYSEPSDE 133 K + V +SGN G AL A +G + +P+T ++ ++AYGA + + S Sbjct: 72 PDKTILVEPTSGNTGIALAMVAAAKGYRLVLTMPETMSLERRAMLKAYGAQLELTPGSQG 131 Query: 134 SRENV--AQRIIQETEGIL-VHPNQEPAVIA-GQGTIALEVLNQVP-LVDALVVPVGGGG 188 + A+ I++ T + + PA + T A E+ LVD ++ VG GG Sbjct: 132 MEGAITRAEEIVENTPNAYSLQQFRNPANPKIHRETTAEEIWADTDGLVDIVIGGVGTGG 191 Query: 189 MVAGIAITIKTLKPSVKVYAAEPSNADDCYQSKLKGELTPNLHPPETIADGVKSSIGLNT 248 + GIA TIK +P + A EPSN+ P H + I G +I Sbjct: 192 TITGIAETIKPRRPQFQAIAVEPSNSPVLSGG------QPGPHKIQGIGAGFIPAI---- 241 Query: 249 WPIIRDLVDDVFTVTEDEIKYATQLVWERMKLLIEPTAGVGLAAVLSQHFQTVSPEVKNI 308 +L+D+V V + E + + + LL +AG L A + Q + E K I Sbjct: 242 --FRPELIDEVIIVDDTEAFAYARRLARQEGLLSGISAGAALWAAI-QVGKRPENEDKLI 298 Query: 309 CIV-LSGGNVDLTS 321 ++ S G L++ Sbjct: 299 VMIQPSFGERYLST 312 >5XEM-A nrPDB Length = 310 Score = 202 bits (513), Expect = 2e-52, Method: Composition-based stats. Identities = 64/316 (20%), Positives = 128/316 (40%), Gaps = 16/316 (5%) Query: 12 VEKAHLNIQDSVHLTPVLTSSILNQIAGRNLFFKCELFQKTGSFKIRGALNAIRGLIPDT 71 + ++ D + TP++ + ++ G ++ K E S K R AL I + Sbjct: 3 LGSLANSVIDLIGNTPLVKINNID-TFGNEIYVKLEGSNPGRSTKDRIALKMIEEAEKEG 61 Query: 72 LEGKPKAVVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPNCKKLAIQAYGASIVYSEPS 131 L K ++ +SGN G L ++ IV+P T + ++AYG ++ ++ S Sbjct: 62 LIDKDTVIIEATSGNTGIGLAMICAVKNYKLKIVMPDTMSIERIQLMRAYGTEVILTDGS 121 Query: 132 DESRENVAQ-RIIQETEGILVHPNQEPAV---IAGQGTIALEVLNQV-PLVDALVVPVGG 186 + + + +++ E PNQ V A T A E+L + VD + G Sbjct: 122 LGMKACLEKLEELKKNEKKYFVPNQFTNVNNPKAHYETTAEEILKDLNNKVDVFICGTGT 181 Query: 187 GGMVAGIAITIKTLKPSVKVYAAEPSNADDCYQSKLKGELTPNLHPPETIADGVKSSIGL 246 GG +G A +K P++K + EP+++ KG + P+ ++ G ++ Sbjct: 182 GGSFSGTAKKLKEKLPNIKTFPVEPASSPLLS----KGYIGPHKIQGMGMSIGGIPAVYD 237 Query: 247 NTWPIIRDLVDDVFTVTEDEIKYATQLVWERMKLLIEPTAGVGLAAVLSQHFQTVSPEVK 306 + L DD+ +D+ + + + +L + G A L + +K Sbjct: 238 GS------LADDILVCEDDDAFEMMRELSFKEGILGGISTGATFKAALDYSKENADKGLK 291 Query: 307 NICIVLSGGNVDLTSL 322 + + G L+++ Sbjct: 292 IVVLSTDSGEKYLSNI 307 >5D84-A nrPDB Length = 326 Score = 196 bits (499), Expect = 9e-51, Method: Composition-based stats. Identities = 69/324 (21%), Positives = 121/324 (37%), Gaps = 33/324 (10%) Query: 9 FADVEKAHLNIQDSVHLTPVLTSSILNQIAGRNLFFKCELFQKTGSFKIRGALNAIRGLI 68 + H ++ DSV TP++ L +F K E GS K R A I I Sbjct: 2 IEKSQACHDSLLDSVGQTPMVQLHQL--FPKHEVFAKLEYMNPGGSMKDRPAKYIIEHGI 59 Query: 69 PDTLEGKPKAVVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPNCKKLAIQAYGASIVYS 128 L + ++ +SGN G AL AK++G+ VV I++YGA++ Sbjct: 60 KHGLITENTHLIESTSGNLGIALAMIAKIKGLKLTCVVDPKISPTNLKIIKSYGANVEMV 119 Query: 129 EPSDESRENVAQRIIQ---------ETEGILVHPN--QEPAVIAGQGTIALEVLNQVPLV 177 E D + RI + + I + N + G GT +E + Q + Sbjct: 120 EEPDAHGGYLMTRIAKVQELLATIDDAYWINQYANELNWQSHYHGAGTEIVETIKQ--PI 177 Query: 178 DALVVPVGGGGMVAGIAITIKTLKPSVKVYAAEPSNADDCYQSKLKGELTPNLHPPETIA 237 D V PV G + G++ IK + P+ ++ A + + + EL Sbjct: 178 DYFVAPVSTTGSIMGMSRKIKEVHPNAQIVAVDAKGSVIFGDKPINREL----------- 226 Query: 238 DGVKSSIGLNTWPII--RDLVDDVFTVTEDEIKYATQLVWERMKLLIEPTAGVGLAAVLS 295 IG + P I R ++ V V + + + + + + + G + A + Sbjct: 227 ----PGIGASRVPEILNRSEINQVIHVDDYQSALGCRKLIDYEGIFAGGSTG-SIIAAIE 281 Query: 296 QHFQTVSPEVKNICIVLSGGNVDL 319 Q ++ + I+ G+ L Sbjct: 282 QLITSIEEGATIVTILPDRGDRYL 305 >5I7O-A nrPDB Length = 326 Score = 191 bits (484), Expect = 5e-49, Method: Composition-based stats. Identities = 61/287 (21%), Positives = 110/287 (38%), Gaps = 32/287 (11%) Query: 16 HLNIQDSVHLTPVLTSSILN-------QIAGRNLFFKCELFQKTGSFKIRGALNAIRGLI 68 + ++ ++ TP++ L+ L+ K E TGS K R A+ I Sbjct: 7 YDSLLQALGNTPLVGLQRLSPRWDDGRDGPHVRLWAKLEDRNPTGSIKDRPAVRMIEQAE 66 Query: 69 PDTLEGKPKAVVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPNCKKLAIQAYGASIVYS 128 D L ++ +SGN G +L AA+L+G V+P+ ++ ++ YGA I++S Sbjct: 67 ADGLLRPGATILEPTSGNTGISLAMAARLKGYRLICVMPENTSVERRQLLELYGAQIIFS 126 Query: 129 --EPSDESRENVAQRIIQETE-GILVHPNQEPAVI-AGQGTIALEVLNQVPLVDALVVPV 184 E + A+ + ++++ PA + E+L +P + V + Sbjct: 127 AAEGGSNTAVATAKELAATNPSWVMLYQYGNPANTDSHYCGTGPELLADLPEITHFVAGL 186 Query: 185 GGGGMVAGIAITIKTLKPSVKVYAAEPSNADDCYQSKLKGE-LTPNLHPPETIADGVKSS 243 G G + G ++ +VK+ AAEP + Y + E P L+ PE + Sbjct: 187 GTTGTLMGTGRFLREHVANVKIVAAEPRYGEGVYALRNMDEGFVPELYDPEILTA----- 241 Query: 244 IGLNTWPIIRDLVDDVFTVTEDEIKYATQLVWERMKLLIEPTAGVGL 290 R V V V T+ + + + G L Sbjct: 242 ---------RYSVGAVDAVRR------TRELVHTEGIFAGISTGAVL 273 >5B1I-A nrPDB Length = 311 Score = 186 bits (472), Expect = 1e-47, Method: Composition-based stats. Identities = 62/317 (19%), Positives = 115/317 (36%), Gaps = 24/317 (7%) Query: 19 IQDSVHLTPVLTSSILNQIAGRNLFFKCELFQKTGSFKIRGALNAIRGLIPDTLEGKPKA 78 +Q+ + TP++ + +++ K E+F GS R I + Sbjct: 6 VQELIGHTPLMALP-IEVPNHSHIYAKLEMFNPGGSIADRLGAYLIEDGLQRGRVNAKTT 64 Query: 79 VVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPNCKKLAIQAYGASIVYSEPSDE--SRE 136 ++ ++GN G L A + + +VVP+ K++ +QA GA IV++ + Sbjct: 65 IIEPTAGNTGIGLALATQAHHLRTILVVPEKFSMEKQVLMQALGAEIVHTPSEEGIKGAI 124 Query: 137 NVAQRIIQETEGILVH-PNQEPAVI-AGQGTIALEVLNQVP-LVDALVVPVGGGGMVAGI 193 A+ + V + PA A T+A E+L +P + A V G GG AG+ Sbjct: 125 RKAEALAATISNSYVPMQFKNPANPAAYYHTLAPEILADMPAPITAFVAGAGSGGTFAGV 184 Query: 194 AITIKTLKPSVKVYAAEPSNADDCYQSKLKGELTPNLHPPETIADGVKSSIGLNTWPIIR 253 A ++ + K EP + + + H E I G+ P Sbjct: 185 AAYLQAQDSATKAVVVEPEGS-------ILNGGPAHAHRTEGI--------GVEFIPPFF 229 Query: 254 D--LVDDVFTVTEDEIKYATQLVWERMKLLIEPTAGVGLAAVLSQHFQTVSPEVKNICIV 311 D +D T+ +++ + + LLI ++ A Q + + I Sbjct: 230 DQVRIDQTLTIADNDAFAQVRHLARDHGLLIGSSS-GAALAASLQLATNLPANSHIVTIF 288 Query: 312 LSGGNVDLTSLSWVKQA 328 L+ + K Sbjct: 289 PDSSERYLSQKIYTKLE 305 >2ZSJ-A nrPDB Length = 352 Score = 185 bits (469), Expect = 3e-47, Method: Composition-based stats. Identities = 71/307 (23%), Positives = 128/307 (41%), Gaps = 31/307 (10%) Query: 24 HLTPVLTSSILNQIAG--RNLFFKCELFQKTGSFKIRGALNAIRGLIPDTLEGKPKAVVT 81 TP++ + L + G ++ K E TGSFK RG AI +E +AV+ Sbjct: 29 GNTPLIEADNLARAIGFKGKIYLKYEGLNPTGSFKDRGMTLAIS----KAVEAGKRAVIC 84 Query: 82 HSSGNHGQALTYAAKLEGIPAYIVVPQTAPNCKKLA-IQAYGASIVYSEPSDESRENVAQ 140 S+GN + A G+ AY+++P+ A KL+ YGA ++ + + + N+ + Sbjct: 85 ASTGNTSASAAAYAARAGLRAYVLLPKGAVAIGKLSQAMIYGAKVLAIQGTFDDALNIVR 144 Query: 141 RIIQETEGILVHPNQEPAVIAGQGTIALEVLNQVPLV-DALVVPVGGGGMVAGIAITIK- 198 +I + + + + P I GQ T A E+ + + D +PVG G + K Sbjct: 145 KIGENFP-VEIVNSVNPYRIEGQKTAAFEICDTLGEAPDYHFIPVGNAGNITAYWKGFKI 203 Query: 199 -------TLKPSVKVYAAEPSNADDCYQSKLKGELTPNLHPPETIADGVKSSIGLNTW-- 249 T P + + AE + +KG N P+TIA +K +W Sbjct: 204 YYEEGKITKLPRMMGWQAEGA------APIVKGYPIKN---PQTIATAIKIG-NPYSWKS 253 Query: 250 --PIIRDLVDDVFTVTEDEIKYATQLVWERMKLLIEPTAGVGLAAVLSQHFQTVSPEVKN 307 ++ + V++ EI YA +L+ + EP + +A ++ + + Sbjct: 254 ALKAAQESGGKIDAVSDSEILYAYKLIASTEGVFCEPASAASVAGLIKLVREGFFKGGEV 313 Query: 308 ICIVLSG 314 + L+G Sbjct: 314 VTCTLTG 320 >3X43-A nrPDB Length = 332 Score = 184 bits (468), Expect = 3e-47, Method: Composition-based stats. Identities = 69/316 (21%), Positives = 124/316 (39%), Gaps = 21/316 (6%) Query: 15 AHLNIQDSVHLTPVLTSSILNQIAGRNLFFKCELFQKTGSFKIRGALNAIRGLIPDTLEG 74 +I D++ TP++ + +++ K E F GS K R AL+ + L Sbjct: 3 LFNSILDTIGRTPIVRLQRMA-PEHTSVYVKVESFNPGGSVKDRLALSVVLDAEAKGLLK 61 Query: 75 KPKAVVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPNCKKLAIQAYGASIVYSEPSDES 134 +V +SGN G AL A G V+ T ++ I+AYG +V S Sbjct: 62 PGDTIVECTSGNVGIALAMVAAARGYRFVAVMGDTYSVERRKLIRAYGGKLVLFPGHLGS 121 Query: 135 REN--VAQRIIQETEGILVHPNQEPAVIAGQ-GTIALEVLNQV--PLVDALVVPVGGGGM 189 + +A + ++ PA + T A E+L +D V G G Sbjct: 122 KGGNLIADELAEKYGWFRARQFDNPANPSYHRETTASEILADFAGKRLDHFVTGFGTTGT 181 Query: 190 VAGIAITIKTLKPSVKVYAAEPSNADDCYQSKLKGELTPNLHPPETIADGVKSSIGLNTW 249 + G+ ++ +P V+V A EPSNA + + H + +A + Sbjct: 182 LTGVGQMLRVARPEVRVVALEPSNAAMLARG------EWSPHQIQGLAPNFVPGV----- 230 Query: 250 PIIRDLVDDVFTVTEDEIKYATQLVWERMKLLIEPTAGVGLAAVLSQHFQTVSPEVKNIC 309 + R ++DD+ T+ E + ++ + + +AG +A LS +PE + Sbjct: 231 -LDRSVIDDLVTMDEVTARDTSRRLAAEEGIFAGISAGATVATALS--IAEHAPEGTVLL 287 Query: 310 IVLSG-GNVDLTSLSW 324 +L G L++ + Sbjct: 288 AMLPDTGERYLSTFLF 303 >3T4P-A nrPDB Length = 334 Score = 184 bits (467), Expect = 4e-47, Method: Composition-based stats. Identities = 64/328 (19%), Positives = 122/328 (37%), Gaps = 21/328 (6%) Query: 6 CISFADVEKAHLNIQDSVHLTPVLTSSILNQIAGRNLFFKCELFQKTGSFKIRGALNAIR 65 F + +I + TP L + LN + K E S K R Sbjct: 2 AAPFDKSKNVAQSIDQLIGQTPALYLNKLNN-TKAKVVLKMECENPMASVKDRLGFAIYD 60 Query: 66 GLIPDTLEGKPKAVV-THSSGNHGQALTYAAKLEGIPAYIVVPQTAPNCKKLAIQAYGAS 124 + K++V SSGN G +L + + G I +P++ ++ ++ +GA Sbjct: 61 KAEKEGKLIPGKSIVVESSSGNTGVSLAHLGAIRGYKVIITMPESMSLERRCLLRIFGAE 120 Query: 125 IVYSEPSDESRENV--AQRIIQETEG-ILVHPNQEPAV-IAGQGTIALEVLNQVPL-VDA 179 ++ + + + V A++I+ +L + + T E+ Q VD Sbjct: 121 VILTPAALGMKGAVAMAKKIVAANPNAVLADQFATKYNALIHEETTGPEIWEQTNHNVDC 180 Query: 180 LVVPVGGGGMVAGIAITIKTLKPSVKVYAAEPSNADDCYQSKLKGELTPNLHPPETIADG 239 + VG GG + G+A +K + ++ A EP+ + K P H + I G Sbjct: 181 FIAGVGTGGTLTGVARALKKMGSHARIVAVEPTESPVLSGGK------PGPHKIQGIGPG 234 Query: 240 VKSSIGLNTWPIIRDLVDDVFTVT-EDEIKYATQLVWERMKLLIEPTAGVGLAAVLSQHF 298 + + R L+D+V V +D I+ A +L + + G + A L Sbjct: 235 FVPDV------LDRSLIDEVLCVAGDDAIETALKLTRSD-GVFCGFSGGANVYAALKIAE 287 Query: 299 QTVSPEVKNICIVLSGGNVDLTSLSWVK 326 + + ++ S G L++ + Sbjct: 288 RPEMEGKTIVTVIPSFGERYLSTTLYRS 315 >2D1F-A nrPDB Length = 360 Score = 178 bits (452), Expect = 3e-45, Method: Composition-based stats. Identities = 64/302 (21%), Positives = 120/302 (39%), Gaps = 22/302 (7%) Query: 24 HLTPVLTSSILNQIAGRNLFFKCELFQKTGSFKIRGALNAIRGLIPDTLEGKPKAVVTHS 83 TP++ ++ L++ G + K E TGSFK RG A+ D L +AV+ S Sbjct: 37 GGTPLIAATNLSKQTGCTIHLKVEGLNPTGSFKDRGMTMAV----TDALAHGQRAVLCAS 92 Query: 84 SGNHGQALTYAAKLEGIPAYIVVPQTAPNCKKLAIQ-AYGASIVYSEPSDESRENVAQRI 142 +GN + A GI +++PQ KLA +GA I+ + + + +A+++ Sbjct: 93 TGNTSASAAAYAARAGITCAVLIPQGKIAMGKLAQAVMHGAKIIQIDGNFDDCLELARKM 152 Query: 143 IQETEGILVHPNQEPAVIAGQGTIALEVLNQVPLV-DALVVPVGGGGMVAGIAITIKT-- 199 + I + + P I GQ T A E+++ + D +PVG G + Sbjct: 153 AADFPTISLVNSVNPVRIEGQKTAAFEIVDVLGTAPDVHALPVGNAGNITAYWKGYTEYH 212 Query: 200 ----LKPSVKVYAAEPSNADDCYQSKLKGELTPNLHPPETIADGVKSSIGLNTWPII--- 252 + ++ + + A + GE + PETIA ++ + + Sbjct: 213 QLGLIDKLPRMLGTQAAGA----APLVLGEPVSH---PETIATAIRIGSPASWTSAVEAQ 265 Query: 253 RDLVDDVFTVTEDEIKYATQLVWERMKLLIEPTAGVGLAAVLSQHFQTVSPEVKNICIVL 312 + +++EI A LV + +EP + +A +L + + Sbjct: 266 QQSKGRFLAASDEEILAAYHLVARVEGVFVEPASAASIAGLLKAIDDGWVARGSTVVCTV 325 Query: 313 SG 314 +G Sbjct: 326 TG 327 >5B55-A nrPDB Length = 340 Score = 177 bits (449), Expect = 6e-45, Method: Composition-based stats. Identities = 73/329 (22%), Positives = 121/329 (36%), Gaps = 29/329 (8%) Query: 13 EKAHLNIQDSVHLTPVLTSSILNQIAGRNLFFKCELFQKTGSFKIRGALNAIRGLIPDTL 72 +K +++ V TP+L + R +F K E + TGS K R A ++ Sbjct: 7 QKKMKYLENLVGKTPMLELIFDYKGEERRIFVKNESYNLTGSIKDRMAFYTLKKAYEKNE 66 Query: 73 EGKPKAVVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPNCKKLAIQAYGASIVYS---E 129 K +V +SGN G A + + G P I +P +K I+++GA I+ E Sbjct: 67 IKKGAPIVEATSGNTGIAFSAMGAILGHPVIIYMPDWMSEERKSLIRSFGAKIILVSRKE 126 Query: 130 PSDESRENVAQRIIQETEGILVHP--NQEPAVIAGQGTIALEVLNQVP----LVDALVVP 183 + + + + A I LE++N++ +D V Sbjct: 127 GGFLGSIEKTKEFAKNNPDTYLPSQFSNLYNSEAHYYGIGLEIVNEMKSLNLNIDGFVAG 186 Query: 184 VGGGGMVAGIAITIKTLKPSVKVYAAEPSNADDCYQSKLKGELTPNLHPPETIADGVKSS 243 VG GG V GI IK + K+ EP N+ P L +A Sbjct: 187 VGTGGTVMGIGKRIKENFSNAKICPLEPLNS-------------PTLSTGYKVAKHRIEG 233 Query: 244 IGLNTWPIIRDL--VDDVFTVTE-DEIKYATQLVWERMKLLIEPTAGVGLAAVLSQHFQT 300 I P + L +D+V +V + D I A +L + L + ++G L Q Sbjct: 234 ISNEFIPDLVKLDKLDNVVSVDDGDAIVMAQKL--AKCGLGVGISSGANFIGAL--MLQN 289 Query: 301 VSPEVKNICIVLSGGNVDLTSLSWVKQAE 329 + I V N S +++ + Sbjct: 290 KLGKDSVIVTVFPDDNKKYLSTDLMREEK 318 >5XCN-X nrPDB Length = 350 Score = 175 bits (443), Expect = 2e-44, Method: Composition-based stats. Identities = 67/307 (21%), Positives = 117/307 (38%), Gaps = 15/307 (4%) Query: 22 SVHLTPVLTSSILNQIAGRNLFFKCELFQKTGSFKIRGALNAIRGLIPDTLEGKPKAVVT 81 S+ TP++ N+ K E + S K R N + D K K +V Sbjct: 44 SIGNTPLVRLKHFGH--NGNVVVKIEGRNPSYSVKCRIGANMVWQAEKDGTLTKGKEIVD 101 Query: 82 HSSGNHGQALTYAAKLEGIPAYIVVPQTAPNCKKLAIQAYGASIVYSEPSDESRENVAQ- 140 +SGN G AL Y A G + +P+T +K + G ++V +E + ++ +A+ Sbjct: 102 ATSGNTGIALAYVAAARGYKITLTMPETMSLERKRLLCGLGVNLVLTEGAKGAKGAIAKA 161 Query: 141 -RIIQETE--GILVHPNQEPAVIA-GQGTIALEVLNQVP-LVDALVVPVGGGGMVAGIAI 195 I+ +++ + PA + T E+ VD +V VG GG + GI+ Sbjct: 162 EEIVASDPSRYVMLKQFENPANPQIHRETTGPEIWKDTDGKVDVVVAGVGTGGSITGISR 221 Query: 196 TIK-TLKPSVKVYAAEPSNADDCYQSKLKGELTPNLHPPETIADGVKSSIGLNTWPIIRD 254 IK + A EP + Q+ E+ P H + I G + Sbjct: 222 AIKLDFGKQITSVAVEPVESPVISQTLAGEEVKPGPHKIQGIGAGFIPK------NLDLS 275 Query: 255 LVDDVFTVTEDEIKYATQLVWERMKLLIEPTAGVGLAAVLSQHFQTVSPEVKNICIVLSG 314 ++D V TV D + + +L ++G +AA + + I+ S Sbjct: 276 IIDRVETVDSDTALATARRLMAEEGILAGISSGAAVAAADRLAKLPEFADKLIVVILPSA 335 Query: 315 GNVDLTS 321 L++ Sbjct: 336 SERYLST 342 >5YGR-A nrPDB Length = 404 Score = 170 bits (430), Expect = 8e-43, Method: Composition-based stats. Identities = 61/327 (18%), Positives = 129/327 (39%), Gaps = 44/327 (13%) Query: 11 DVEKAHLNIQDSVHLTPVLTSSILNQIAG-RNLFFKCELFQKT-GSFKIRGALNAIRGLI 68 +V H + + +TP+ + L+Q G ++ K E ++ +FK G A+ + Sbjct: 32 EVLAFHKKLPNYA-VTPLHNLAHLSQRLGLGSIHIKDESWRFGLNAFKGLGGSYAVGKYL 90 Query: 69 PDTLEG-------------------KPKAVVTHSSGNHGQALTYAAKLEGIPAYIVVPQT 109 D L+ K VT + GNHG+ + +AA+ G+ A + +P+ Sbjct: 91 ADKLQCDINSLSFAALNTPEIKEKIKDCVFVTATDGNHGRGVAWAAEQLGLKAVVYMPKG 150 Query: 110 APNCKKLAIQAYGASIVYSEPSDESRENVAQRIIQETEGILVHPNQEPA-------VIAG 162 + + I+ +GA ++ + + +A R+ Q +L+ ++ G Sbjct: 151 SSLIRAENIRHHGAECTITDLNYDDAVRLAHRMAQTKGWVLLQDTAWTGYEEIPTWIMQG 210 Query: 163 QGTIALEVLNQV-----PLVDALVVPVGGGGMVAGI-AITIKTLKPSVK-VYAAEPSNAD 215 T+A+E Q+ PL L++ G G + ++ ++ ++ + EP A+ Sbjct: 211 YMTLAVEAYEQLAETNSPLPTHLILQAGVGSFAGSVMGYFVEKMQENIPNIIVVEPHQAN 270 Query: 216 DCYQSKLKGELTPNLHPPE--TIADGVKSS-IGLNTWPIIRDLVDDVFTVTEDEIKYATQ 272 YQS + + P+ + TI G+ + +WPIIRD + + + Sbjct: 271 CLYQSAVMDDGQPHCVTGDMATIMAGLACGEPNIISWPIIRDNTSCFISADDCLAAKGMR 330 Query: 273 LVWE-----RMKLLIEPTAGVGLAAVL 294 + + + +G+ + Sbjct: 331 ISAAPRPGTDTPFISGESGAIGVGLLY 357 >1UIN-A nrPDB Length = 351 Score = 170 bits (430), Expect = 9e-43, Method: Composition-based stats. Identities = 73/326 (22%), Positives = 127/326 (38%), Gaps = 30/326 (9%) Query: 24 HLTPVL--TSSILNQIAGRNLFFKCELFQKTGSFKIRGALNAIRGLIPDTLEGKPKAVVT 81 TP++ + G L+ K E TGSFK RG A+ +EG +AV Sbjct: 27 GSTPLIPLKGPEEARKKGIRLYAKYEGLNPTGSFKDRGMTLAVS----KAVEGGAQAVAC 82 Query: 82 HSSGNHGQALTYAAKLEGIPAYIVVPQTAPNCKKLAIQ-AYGASIVYSEPSDESRENVAQ 140 S+GN + A GI A +V+P K+A +GA IV E + + + Q Sbjct: 83 ASTGNTAASAAAYAARAGILAIVVLPAGYVALGKVAQSLVHGARIVQVEGNFDDALRLTQ 142 Query: 141 RIIQETEGILVHPNQEPAVIAGQGTIALEVLNQVPLV-DALVVPVGGGGMVAGIAITIKT 199 ++ + LV+ + P + GQ T+A EV++++ +PVG G + + K Sbjct: 143 KLTEAFPVALVN-SVNPHRLEGQKTLAFEVVDELGDAPHYHALPVGNAGNITAHWMGYKA 201 Query: 200 LK--------PSVKVYAAEPSNADDCYQSKLKGELTPNLHPPETIADGVKSSIGLNTWPI 251 P + + A + G PET+A ++ + Sbjct: 202 YHALGKAKRLPRMLGFQA------AGAAPLVLGRPVE---RPETLATAIRIGNPASWQGA 252 Query: 252 IR---DLVDDVFTVTEDEIKYATQLVWERMKLLIEPTAGVGLAAVLSQHFQTVSPEVKNI 308 +R + + VT++EI +A + + + EP + +A V + + Sbjct: 253 VRAKEESGGVIEAVTDEEILFAYRYLAREEGIFCEPASAAAMAGVFKLLREGRLEPESTV 312 Query: 309 CIVLSG-GNVDLTSLSWVKQAERPAP 333 + L+G G D + V + P P Sbjct: 313 VLTLTGHGLKDPATAERVAELPPPVP 338 >4D9G-A nrPDB Length = 398 Score = 157 bits (396), Expect = 8e-39, Method: Composition-based stats. Identities = 64/344 (18%), Positives = 130/344 (37%), Gaps = 44/344 (12%) Query: 26 TPVLTSSILNQIAG-RNLFFKCELFQKT-GSFKIRGALNAIRGLIPDT------------ 71 TP+ L + G + + K E + +FK+ G AI L+ + Sbjct: 45 TPLCALDDLANLFGVKKILVKDESKRFGLNAFKMLGGAYAIAQLLCEKYHLDIETLSFEH 104 Query: 72 ---LEGKPKAVVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPNCKKLAIQAYGASIVYS 128 G+ T + GNHG+ + +AA+ G A I +P+ + + AI GA + + Sbjct: 105 LKNAIGEKMTFATTTDGNHGRGVAWAAQQLGQNAVIYMPKGSAQERVDAILNLGAECIVT 164 Query: 129 EPSDESRENVAQRIIQETEGILVHPNQEPA-------VIAGQGTIALEVLNQVPLV---- 177 + + + + + Q+ +V ++ G T+A E + Q+ + Sbjct: 165 DMNYDDTVRLTMQHAQQHGWEVVQDTAWEGYTKIPTWIMQGYATLADEAVEQMREMGVTP 224 Query: 178 DALVVPVGGGGMVAGI-AITIKTLKP-SVKVYAAEPSNADDCYQSKLKGELTPNLHPPET 235 +++ G G M G+ + P ++ EP AD Y+S +KG++ T Sbjct: 225 THVLLQAGVGAMAGGVLGYLVDVYSPQNLHSIIVEPDKADCIYRSGVKGDIVNVGGDMAT 284 Query: 236 IADGVKSSIGL-NTWPIIRDLVDDVFTVTEDEIKYATQLV----WERMKLLIEPTA--GV 288 I G+ W I+R+ + + +++ +++ + G+ Sbjct: 285 IMAGLACGEPNPLGWEILRNCATQFISCQDSVAALGMRVLGNPYGNDPRIISGESGAVGL 344 Query: 289 GLAAVLSQHFQTVSPEVKN-------ICIVLSGGNVDLTSLSWV 325 G+ A + H Q S K + ++ + G+ D+ V Sbjct: 345 GVLAAVHYHPQRQSLMEKLALNKDAVVLVISTEGDTDVKHYREV 388 >3VSD-A nrPDB Length = 389 Score = 118 bits (296), Expect = 3e-27, Method: Composition-based stats. Identities = 60/306 (19%), Positives = 111/306 (36%), Gaps = 31/306 (10%) Query: 26 TPVLTSSILNQIAGRNLFFKCELFQK-TGSFKIRGALNAIRGLIPDTLEGKPKAVVTHSS 84 TP++ S L G ++ K E + + S R A+ I L K V +S Sbjct: 97 TPLVRS-RLQLPNGVRVWLKLEWYNPFSLSVADRPAVEIISRLSRR--VEKGSLVADATS 153 Query: 85 GNHGQALTYAAKLEGIPAYIVVPQTAPNCKKLAIQAYGASIVYSEPSDESRENVAQRI-- 142 N G AL+ A+L G A + +P A KL + GA ++ + + + + + Sbjct: 154 SNFGVALSAVARLYGYRARVYLPGAAEEFGKLLPRLLGAQVIVDPEAPSTVHLLPRVMKD 213 Query: 143 IQETEGILVHPNQEPAVIAGQG-TIALEVLNQVPLVDALVVPV----GGGGMVAGIAITI 197 + + V+ A A E+ Q + V G G ++ A + Sbjct: 214 SKNEGFVHVNQFYNDANFEAHMRGTAREIFVQSRRGGLALRGVAGSLGTSGHMSAAAFYL 273 Query: 198 KTLKPSVKVYAAEPSNADDCYQSKLKGELTPNLHPPETIADGVKSSIGLNTWPIIRDLVD 257 +++ PS++ +P+ G+ P + ET W + D+ Sbjct: 274 QSVDPSIRAVLVQPAQ----------GDSIPGIRRVET----------GMLWINMLDISY 313 Query: 258 DVFTVTEDEIKYATQLVWERMKLLIEPTAGVGLAAVLSQHFQTVSPEVKNICIVLSGGNV 317 + VT +E A V L+I P+ G + A+ + + + +V G Sbjct: 314 TLAEVTLEEAMEAVVEVARSDGLVIGPSGGAAVKALAKKAAEGDLEPGDYVVVVPDTGFK 373 Query: 318 DLTSLS 323 L+ + Sbjct: 374 YLSLVQ 379 >1E5X-A nrPDB Length = 486 Score = 118 bits (295), Expect = 4e-27, Method: Composition-based stats. Identities = 65/337 (19%), Positives = 115/337 (34%), Gaps = 34/337 (10%) Query: 6 CISFADVEKAHLNIQDSVHLTPVLTSSILNQIA--GRNLFFKCELFQKTGSFKIRGALNA 63 I D+ A + + + + +L+ K TGSFK G Sbjct: 117 EIDDDDIVSAFE------GNSNLFWAERFGKQFLGMNDLWVKHCGISHTGSFKDLGMTVL 170 Query: 64 IRGLIP-DTLEGKPKAVVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPNCKKLAIQ-AY 121 + + ++ V S+G+ AL+ GIP+ + +P + +L A Sbjct: 171 VSQVNRLRKMKRPVVGVGCASTGDTSAALSAYCASAGIPSIVFLPANKISMAQLVQPIAN 230 Query: 122 GASIVYSEPSDESRENVAQRIIQETEGILVHPNQEPAVIAGQGTIALEVLNQVP--LVDA 179 GA ++ + + + + I E I + + + GQ T A+E+L Q + D Sbjct: 231 GAFVLSIDTDFDGCMKLIREITAELP-IYLANSLNSLRLEGQKTAAIEILQQFDWQVPDW 289 Query: 180 LVVPVGGGGMVAGIAITIK--------TLKPSVKVYAAEPSNADDCYQSKLKGELTPNLH 231 ++VP G G + K P + A+ +NA+ Y G Sbjct: 290 VIVPGGNLGNIYAFYKGFKMCQELGLVDRIPRM--VCAQAANANPLYLHYKSGWKDFKPM 347 Query: 232 PPET-------IADGVKSSIGLNTWPIIRDLVDDVFTVTEDEIKYATQLVWERMKLLIEP 284 T I D V + +V++ TE+E+ A + + I P Sbjct: 348 TASTTFASAIQIGDPVSIDRAVYALKKCNGIVEE---ATEEELMDAMAQ-ADSTGMFICP 403 Query: 285 TAGVGLAAVLSQHFQTVSPEVKNICIVLSGGNVDLTS 321 GV L A+ Q V +V + + T Sbjct: 404 HTGVALTALFKLRNQGVIAPTDRTVVVSTAHGLKFTQ 440 >6HUL-B nrPDB Length = 425 Score = 97.9 bits (242), Expect = 6e-21, Method: Composition-based stats. Identities = 62/356 (17%), Positives = 115/356 (32%), Gaps = 59/356 (16%) Query: 22 SVHL-TPVLTSSILNQ--IAGRNLFFKCELFQKTGSFKIRGALNAIRGLIPDTLEGKPKA 78 S+ TP+ + L + ++FK E TGS KI A I EG Sbjct: 71 SIGRPTPLFRAKRLEEYLKTPARIYFKYEGATPTGSHKINTA---IPQAYFAKEEGIEHV 127 Query: 79 VVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPNCK---KLAIQAYGASIVYSEPSDESR 135 V +G G A+ AA + + + I + + + K + +Q YGA++ S + Sbjct: 128 VTETGAGQWGTAVALAASMYNMKSTIFMVKVSYEQKPMRRSIMQLYGANVYASPTNLTEY 187 Query: 136 ENV------------------AQRIIQETEGILVHPNQEPAVIAGQGTIALEVLNQVP-- 175 A + E + + V+ Q I E + Q+ Sbjct: 188 GRKILETNPQHPGSLGIAMSEAIEYALKNEFRYLVGSVLDVVLLHQSVIGQETITQLDLL 247 Query: 176 --LVDALVVPVGGGGMVAGIAITIKTLKPSVKVYAAEPSNADDCYQSKL----------- 222 D L+ VGGG G K + A + + + Sbjct: 248 GEDADILIGCVGGGSNFGGFTYPFIGNKKGKRYIAVSSAEIPKFSKGEYKYDFPDSAGLL 307 Query: 223 ---------KGELTPNLHPPETIADGVKSSIGLNTWPIIRDLVDDVFTVTEDEIKYATQL 273 K + P ++ GV ++ L T ++ + + E EI A ++ Sbjct: 308 PLVKMITLGKDYVPPPIYAGGLRYHGVAPTLSLLT----KEGIVEWREYNEREIFEAAKI 363 Query: 274 VWERMKLLIEPTAGVGLAAVLSQHFQTVSPEVKNICIVLSGGNVDLTSLSWVKQAE 329 E ++ P + + AV+ + + + + + N+ L + E Sbjct: 364 FIENQGIVPAPESAHAIRAVVDEAIEARKNNERKVIVF----NLSGHGLLDLSNYE 415 >5EY5-B nrPDB Length = 399 Score = 94.0 bits (232), Expect = 8e-20, Method: Composition-based stats. Identities = 67/347 (19%), Positives = 122/347 (35%), Gaps = 51/347 (14%) Query: 19 IQDSVHL-TPVLTSSILNQIAGR-NLFFKCELFQKTGSFKIRGALNAIRGLIPDTLEGKP 76 ++D V TP+ + L + G ++ K E TG+ KI NA+ + GK Sbjct: 43 LRDYVGRPTPLYFAENLTKDLGGAKIYLKREDLNHTGAHKIN---NALGQALLAKRMGKK 99 Query: 77 KAVVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPNCKKLA-----IQAYGASI------ 125 + + +G HG A A + G+ + + A + ++ A ++ GA + Sbjct: 100 RVIAETGAGQHGVATATVAAMFGLECVVYM--GAEDIERQALNVFRMKLLGAKVRPVTSG 157 Query: 126 --VYSEPSDESRENVAQRIIQETEGILVHPNQEPAVI---AGQGTIALEVLNQV-----P 175 + +E+ + + I P + Q I E Q+ Sbjct: 158 SRTLKDAINEAMRDWVTNVEDTFYIIGSVVGPHPYPMMVRDFQSVIGEEARQQILEKEGR 217 Query: 176 LVDALVVPVGGGGMVAGIAITIKTLKPSVKVYAAEPSNA---DDCYQSKLKGELTPNLH- 231 L DA+V VGGG GI SV++ E + + + L LH Sbjct: 218 LPDAIVACVGGGSNAMGIFHPF-IDDESVRLIGVEAAGKGIETGKHAATLSAGRPGVLHG 276 Query: 232 --------------PPETIADGVK-SSIGLNTWPIIRDLVDDVFTVTEDEIKYATQLVWE 276 +I+ G+ +G + + +VT+DE A QL+ Sbjct: 277 AMTYLLQDEDGQIIEAHSISAGLDYPGVGPEHAYLKDTGRAEYVSVTDDEALEAFQLLSR 336 Query: 277 RMKLLIEPTAGVGLAAVLSQHFQTVSPEVKNICIVLSG-GNVDLTSL 322 ++ P A + + + I + LSG G+ D+ ++ Sbjct: 337 TEGII--PALESSHAVAYAMKLAPELSKDQIIVVNLSGRGDKDVNTV 381 >5OCW-B nrPDB Length = 442 Score = 89.8 bits (221), Expect = 1e-18, Method: Composition-based stats. Identities = 67/354 (18%), Positives = 116/354 (32%), Gaps = 50/354 (14%) Query: 9 FADVEKAHLNIQDSVHLTPVLTSSILNQIAG-RNLFFKCELFQKTGSFKIRGALNAIRGL 67 D+++ N +P+ ++ L+Q AG +F K E TGS KI N + Sbjct: 87 LDDLDRLQANYAGR--PSPLYEATRLSQHAGSARIFLKREDLNHTGSHKIN---NVLGQA 141 Query: 68 IPDTLEGKPKAVVTHSSGNHGQALTYAAKLEGIPAYIVV---PQTAPNCKKLAIQAYGAS 124 + GK + + +G HG A A L G+ I + ++ GA Sbjct: 142 LLARRMGKTRVIAETGAGQHGVATATACALLGLDCVIYMGGIDTARQALNVARMRLLGAE 201 Query: 125 IVYSEPS----DESRENVAQRIIQETEGIL--------VHPNQEPAVIAGQGTIALE--- 169 +V + ++ + + + HP V Q I +E Sbjct: 202 VVAVQTGSKTLKDAINEAFRDWVANADNTYYCFGTAAGPHPF-PTMVRDFQRIIGMEARV 260 Query: 170 -VLNQVPLV-DALVVPVGGGGMVAGIAITIKTLKPSVKVYAAEPS--------------- 212 + Q + DA+V VGGG GI P V++ E + Sbjct: 261 QIQGQAGRLPDAVVACVGGGSNAIGIFHAFLD-DPGVRLVGFEAAGDGVETGRHAATFTA 319 Query: 213 ---NADDCYQSKLKGELTPNLHPPETIADGVK-SSIGLNTWPIIRDLVDDVFTVTEDEIK 268 A S L + +I+ G+ +G + D +T+ E Sbjct: 320 GSPGAFHGSFSYLLQDEDGQTIESHSISAGLDYPGVGPEHAWLKEAGRVDYRPITDSEAM 379 Query: 269 YATQLVWERMKLLIEPTAGVGLAAVLSQHFQTVSPEVKNICIVLSG-GNVDLTS 321 A L+ ++ + +A L I + LSG G+ D+ + Sbjct: 380 DAFGLLCRMEGIIPAIESAHAVAGALK--LGVELGRGAVIVVNLSGRGDKDVET 431 >5KZM-B nrPDB Length = 396 Score = 88.6 bits (218), Expect = 3e-18, Method: Composition-based stats. Identities = 62/373 (16%), Positives = 125/373 (33%), Gaps = 59/373 (15%) Query: 3 AQYCISFADVEKAHLNIQDSVHL-TPVLTSSILNQIAGRNLFFKCELFQKTGSFKIRGAL 61 AQ SF ++ +Q+ T + + + + L+ K E G+ K Sbjct: 34 AQADESFK--QEFKELLQEYAGRPTALTKTRNIVKNTRTKLYLKREDLLHGGAHK---TN 88 Query: 62 NAIRGLIPDTLEGKPKAVVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPNCK---KLAI 118 + + GK + + +G HG A A L + + + + + Sbjct: 89 QVLGQALLAKRMGKKEIIAETGAGQHGVATALACALLDLKCRVYMGAKDVERQSPNVFRM 148 Query: 119 QAYGASIVYSEPSDESRENVAQRIIQETEGIL------------VHPNQEPAVIAGQGTI 166 + GA ++ + ++ +++ HP V Q I Sbjct: 149 KLMGAEVIPVHSGSATLKDACNEALRDWSANYSKAHYLLGTAAGPHPF-PTIVREFQRMI 207 Query: 167 ALEVLNQV-----PLVDALVVPVGGGGMVAGI-AITIKTLKPSVKVYAAEPSNADDCYQS 220 E Q+ L DA++ VGGG G+ A I +VK+ EP+ + Sbjct: 208 GEETKQQMLAKEGRLPDAVIACVGGGSNAIGMFADFIDE--KNVKLIGVEPAG-----KG 260 Query: 221 KLKGELT-PNLHPPETIADGVKSSIGLNTWPIIRDLVD---------------------- 257 GE P H I G+K+ + N+ I + Sbjct: 261 IETGEHGAPLKHGKTGIFFGMKAPLMQNSDGQIEESYSISAGLDFPSVGPQHAHLLAIGR 320 Query: 258 -DVFTVTEDEIKYATQLVWERMKLLIEPTAGVGLAAVLSQHFQTVSPEVKNICIVLSGGN 316 + T+DE A +L+ ++ ++ + LA L ++ + E + + G+ Sbjct: 321 AKYASATDDEALDAFKLLCKKEGIIPALESSHALAHALKLAYEDPNKEQLLVVNLSGRGD 380 Query: 317 VDLTSLSWVKQAE 329 D+ ++ + + + Sbjct: 381 KDIFTVHDILKEK 393 >5KIN-B nrPDB Length = 407 Score = 88.2 bits (217), Expect = 5e-18, Method: Composition-based stats. Identities = 72/377 (19%), Positives = 122/377 (32%), Gaps = 66/377 (17%) Query: 3 AQYCISFADVEKAHLNIQDSVHL-TPVLTSSILNQIAGR-NLFFKCELFQKTGSFKIRGA 60 +Q SF E+ + ++ V TP+ + L Q G ++ K E TG+ KI Sbjct: 38 SQADPSFQ--EELNQLLRQYVGRETPLYYAKNLTQHIGGAKIYLKREDLNHTGAHKIN-- 93 Query: 61 LNAIRGLIPDTLEGKPKAVVTHSSGNHGQALTYAAKLEGIPAYIVVPQ---TAPNCKKLA 117 NA+ + GK K + +G HG A AA L + I + + Sbjct: 94 -NALGQVWLAKRMGKKKIIAETGAGQHGVATATAAALFNMECTIYMGEEDVKRQALNVFR 152 Query: 118 IQAYGASIVYSEPSDESRENVAQRIIQETEGILVHPNQEPAVIAG--------------- 162 ++ GA + V + + V + I G Sbjct: 153 MELLGAKVEAV----TDGSRVLKDAVNAALRSWVANIDDTHYILGSALGPHPFPEIVRDF 208 Query: 163 QGTIALEVLNQVPLV------DALVVPVGGGGMVAG----------IAITIKTLKPSVKV 206 Q I E Q + DALV VGGG G +A+ Sbjct: 209 QSVIGREAKQQYRDLTGRDLPDALVACVGGGSNAIGLFHPFVEDESVAMYGTEAA----G 264 Query: 207 YAAEPSNADDCYQSKLKGELTPNLHPP-----ETIADGVKSSIGLNTWPIIRDLV--DDV 259 + + G L +L I + S GL+ I + D+ Sbjct: 265 LGVDTEHHAATLTKGRPGVLHGSLMDVLQDAHGQILEAFSISAGLDYPGIGPEHSHYHDI 324 Query: 260 -----FTVTEDEIKYATQLVWERMKLL--IEPTAGVGLAAVLSQHFQTVSPEVKNICIVL 312 VT++E QL+ ++ +E + + A L++ + PE I + Sbjct: 325 KRASYVPVTDEEALEGFQLLSRVEGIIPALESSHAIAFAVKLAKE---LGPEKSMIVCLS 381 Query: 313 SGGNVDLTSLSWVKQAE 329 G+ D+ + +A+ Sbjct: 382 GRGDKDVVQVKDRLEAD 398 >4D9F-A nrPDB Length = 342 Score = 87.5 bits (215), Expect = 8e-18, Method: Composition-based stats. Identities = 59/318 (18%), Positives = 111/318 (34%), Gaps = 34/318 (10%) Query: 20 QDSVHL-TPVLTSSILNQIAGRNLFFKCELFQK--TGSFKIRGALNAIRGLIPDTLEGKP 76 + + TP+ L+ GR ++ K + G K+R + L+ D L Sbjct: 26 LEFIGAPTPLEYLPRLSDYLGREIYIKRDDVTPIAMGGNKLR----KLEFLVADALREGA 81 Query: 77 KAVVTHSS--GNHGQALTYAAKLEGIPAYIVV--PQTAPNCK------KLAIQAYGASIV 126 ++T + NH + A G+ ++ P +L + + I Sbjct: 82 DTLITAGAIQSNHVRQTAAVAAKLGLHCVALLENPIGTTAENYLTNGNRLLLDLFNTQIE 141 Query: 127 YSEP---SDESRENVAQRIIQETEGILVHPNQEPAVIA--GQGTIALEVLNQVPLV---D 178 + D + +A RI + V P + + G ALE+ Q V Sbjct: 142 MCDALTDPDAQLQTLATRIEAQGFRPYVIPVGGSSALGAMGYVESALEIAQQCEEVVGLS 201 Query: 179 ALVVPVGGGGMVAGIAITIKTLKPSVKVYAAEPSNADDCYQSKLKGELTPNLHPPETIAD 238 ++VV G G AG+A+ ++ L P V++ S+ E P + + Sbjct: 202 SVVVASGSAGTHAGLAVGLEHLMPDVELIGV--------TVSRSVAEQKPKVIALQQAIA 253 Query: 239 GVKSSIGLNTWPIIRDLVDDVFTVTEDEIKYATQLVWERMKLLIEPT-AGVGLAAVLSQH 297 G + + D + V D A +L+ +L++P G +A ++ Sbjct: 254 GQLALTATADIHLWDDYFAPGYGVPNDAGMEAVKLLASLEGVLLDPVYTGKAMAGLIDGI 313 Query: 298 FQTVSPEVKNICIVLSGG 315 Q + I + +GG Sbjct: 314 SQKRFNDDGPILFIHTGG 331 >6AMI-A nrPDB Length = 396 Score = 85.5 bits (210), Expect = 3e-17, Method: Composition-based stats. Identities = 64/341 (18%), Positives = 114/341 (33%), Gaps = 46/341 (13%) Query: 26 TPVLTSSILNQIAGR-NLFFKCELFQKTGSFKIRGALNAIRGLIPDTLEGKPKAVVTHSS 84 TP+ + L + G ++ K E G+ K NAI + GK + + + Sbjct: 51 TPLYYAKRLTEKIGGAKVYLKREDLVHGGAHK---TNNAIGQALLAKFMGKTRLIAETGA 107 Query: 85 GNHGQALTYAAKLEGIPAYIVVPQTAPNCKKL---AIQAYGASIV-YSEPSDESRENVAQ 140 G HG A A L G+ I + +K+ ++ GA+++ + S ++ + + Sbjct: 108 GQHGVATAMAGALLGMKVDIYMGAEDVERQKMNVFRMKLLGANVIPVNSGSRTLKDAINE 167 Query: 141 RIIQ-----ETEGILVHPNQEPAVI-----AGQGTIALE----VLNQVPLV-DALVVPVG 185 + E L+ P Q I E +L + D +V VG Sbjct: 168 ALRDWVATFEYTHYLIGSVVGPHPYPTIVRDFQSVIGREAKAQILEAEGQLPDVIVACVG 227 Query: 186 GGGMVAGIAITIKTLKPSVKVYAAEPSN----ADDCYQSKLKGELTP------------- 228 GG GI VK+ E + S G++ Sbjct: 228 GGSNAMGIFYPF-VNDKKVKLVGVEAGGKGLESGKHSASLNAGQVGVSHGMLSYFLQDEE 286 Query: 229 -NLHPPETIADGVK-SSIGLNTWPIIRDLVDDVFTVTEDEIKYATQLVWERMKLLIEPTA 286 + P +IA G+ +G + + + VT++E A + ++ P Sbjct: 287 GQIKPSHSIAPGLDYPGVGPEHAYLKKIQRAEYVAVTDEEALKAFHELSRTEGII--PAL 344 Query: 287 GVGLAAVLSQHFQTVSPEVKNICIVLSG-GNVDLTSLSWVK 326 A + + I + LSG G+ DL + V Sbjct: 345 ESAHAVAYAMKLAKEMSRDEIIIVNLSGRGDKDLDIVLKVS 385 >1X1Q-A nrPDB Length = 418 Score = 84.8 bits (208), Expect = 5e-17, Method: Composition-based stats. Identities = 64/360 (17%), Positives = 130/360 (36%), Gaps = 55/360 (15%) Query: 12 VEKAHLNIQDSVHL-TPVLTSSILNQI-AGRNLFFKCELFQKTGSFKIRGALNAIRGLIP 69 +E+ ++ TP+ + L++ G +F K E TG+ KI N + + Sbjct: 63 LEELDHYLRQFAGRPTPLYHAKRLSEYWGGAQVFLKREDLLHTGAHKIN---NTLGQALL 119 Query: 70 DTLEGKPKAVVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAP---NCKKLAIQAYGASI- 125 GK + + +G HG ++ A L G+ + + + ++ GA + Sbjct: 120 ARRMGKRRVIAETGAGQHGVSVATVAALFGLECVVYMGEEDVRRQALNVFRMKLLGAEVR 179 Query: 126 -------VYSEPSDESRENVAQRIIQETE--GILVHPNQEP-AVIAGQGTIALEVLNQVP 175 + ++E+ + + G +V P+ P V Q I EV Q Sbjct: 180 PVAAGSRTLKDATNEAIRDWITNVRTTFYILGSVVGPHPYPMMVRDFQSVIGEEVKRQSL 239 Query: 176 LV-----DALVVPVGGGGMVAGI---AITIKTLKPSVKVYAAEPSNA-------DDCYQS 220 + DAL+ VGGG G+ + +P K+ E + + Sbjct: 240 ELFGRLPDALIAAVGGGSNAIGLFAPFAYLPEGRP--KLIGVEAAGEGLSTGRHAASIGA 297 Query: 221 KLKG-----------ELTPNLHPPETIADGVK-SSIGLNTWPIIRDLVDDVFTVTEDEIK 268 +G + + P +++ G+ +G V + +VT++E Sbjct: 298 GKRGVLHGSYMYLLYDHDGQITPAHSVSAGLDYPGVGPEHSYYADAGVAEYASVTDEEAL 357 Query: 269 YATQLVWERMKLL--IEPTAGVGLAAVLSQHFQTVSPEVKNICIVLSG-GNVDLTSLSWV 325 +L+ ++ +E + AA + + + + I LSG G+ D+T + + Sbjct: 358 EGFKLLARLEGIIPALESAHAIAYAAKVVPEMD----KDQVVVINLSGRGDKDVTEVMRL 413 >1CX9-B nrPDB Length = 397 Score = 84.0 bits (206), Expect = 8e-17, Method: Composition-based stats. Identities = 61/368 (16%), Positives = 125/368 (33%), Gaps = 53/368 (14%) Query: 2 CAQYCISFADVEKAHLNIQDSVHL-TPVLTSSILNQIAGRNLFFKCELFQKTGSFKIRGA 60 ++ FAD+ +++ T + + L+ K E G+ K Sbjct: 38 DPEFQAQFADL------LKNYAGRPTALTKCQNITAGTRTTLYLKREDLLHGGAHK---T 88 Query: 61 LNAIRGLIPDTLEGKPKAVVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPNCK---KLA 117 + + GK + + +G HG A A+ L G+ I + + Sbjct: 89 NQVLGQALLAKRMGKSEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFR 148 Query: 118 IQAYGASIVYSEPSDESRENVAQRIIQETEGILVHPNQ--------EPA--------VIA 161 ++ GA ++ + ++ +++ G + P + Sbjct: 149 MRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMI 208 Query: 162 GQGTIALEVLNQVPLVDALVVPVGGGGMVAGI-AITIKTLKPSVKVYAAEP--------- 211 G+ T A + + L DA++ VGGG G+ A I SV + EP Sbjct: 209 GEETKAQILDKEGRLPDAVIACVGGGSNAIGMFADFINDT--SVGLIGVEPGGHGIETGE 266 Query: 212 SNADDCYQ--SKLKGELTPNLHPPET-------IADGVK-SSIGLNTWPIIRDLVDDVFT 261 A + G P + + I+ G+ S+G + D + Sbjct: 267 HGAPLKHGRVGIYFGMKAPMMQTADGQIEESYSISAGLDFPSVGPQHAYLNSIGRADYVS 326 Query: 262 VTEDEIKYATQLVWERMKLLIEPTAGVGLAAVLSQHFQTVSPEVKNICIVLSG-GNVDLT 320 +T+DE A + + ++ + LA L + + + + + LSG G+ D+ Sbjct: 327 ITDDEALEAFKTLCRHEGIIPALESSHALAHALK-MMREQPEKEQLLVVNLSGRGDKDIF 385 Query: 321 SLSWVKQA 328 ++ + +A Sbjct: 386 TVHDILKA 393 >4NEG-A nrPDB Length = 400 Score = 83.6 bits (205), Expect = 1e-16, Method: Composition-based stats. Identities = 72/358 (20%), Positives = 129/358 (36%), Gaps = 49/358 (13%) Query: 13 EKAHLNIQDSVHL-TPVLTSSILNQIAGR-NLFFKCELFQKTGSFKIRGALNAIRGLIPD 70 ++ + ++ V TP+ + + + G ++ K E TG+ KI N I + Sbjct: 49 KELNHYLKTYVGRETPLYFAENMTEYCGGAKIYLKREDLNHTGAHKIN---NTIGQALLA 105 Query: 71 TLEGKPKAVVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPNCKKL---AIQAYGASIVY 127 GK K V +G HG A L G+ I + + +KL ++ GA + Sbjct: 106 VRMGKKKVVAETGAGQHGVATATVCALLGLECVIFMGEEDVRRQKLNVFRMELLGAKVES 165 Query: 128 SEPSDESRENVAQRIIQ-------ETEGIL-----VHPNQEPAVIAGQGTIALEVLNQVP 175 + ++ ++ +T I+ HP V Q I E Q Sbjct: 166 VAAGSGTLKDAVNEALRYWVSHVHDTHYIMGSVLGPHPF-PQIVRDFQSVIGNETKKQYE 224 Query: 176 LV-----DALVVPVGGGGMVAGIAITIKTLKPSVKVYAAEPSNADDCYQ----------- 219 + +A+V +GGG G+ V +Y E + + Sbjct: 225 ALEGKLPEAVVACIGGGSNAMGMFYPF-VHDEEVALYGVEAAGKGVHTEKHAATLTKGSV 283 Query: 220 SKLKGELTPNLHPPET-IADGVKSSIGLNTWPIIRD--LVDDVFTVT-----EDEIKYAT 271 L G + L E I + S GL+ + + L+ D+ V+ +DE A Sbjct: 284 GVLHGSMMYLLQNEEGQIQEAHSISAGLDYPGVGPEHSLLKDIGRVSYHSITDDEALEAF 343 Query: 272 QLVWERMKLLIEPTAGVGLAAVLSQHFQTVSPEVKNICIVLSG-GNVDLTSLSWVKQA 328 QL+ ++ ++ + +A L Q E + I LSG G+ D+ S+ + Sbjct: 344 QLLTKKEGIIPALESSHAVAYALKLAPQMKEDEG--LVICLSGRGDKDVESIKRYMEE 399 >3SS9-X nrPDB Length = 442 Score = 74.0 bits (180), Expect = 8e-14, Method: Composition-based stats. Identities = 49/297 (16%), Positives = 98/297 (32%), Gaps = 40/297 (13%) Query: 36 QIAGRNLFFKCELFQK-TGSFKIRGA-LNAIRGLIPDTLEGK------------------ 75 Q L K + +GS K RG + LE Sbjct: 97 QPISGQLLLKKDSHLPISGSIKARGGIYEVLAHAEKLALEAGLLTLDDDYSKLLSPEFKQ 156 Query: 76 ---PKAVVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPNCKKLAIQAYGASIVYSEPSD 132 ++ S+GN G ++ + G + + A KK ++++G ++V E Sbjct: 157 FFSQYSIAVGSTGNLGLSIGIMSARIGFKVTVHMSADARAWKKAKLRSHGVTVVEYEQDY 216 Query: 133 ESRENVAQRIIQETEGILVHPNQEPAVI-AGQGTIALEVLNQVPLVDALV---------V 182 ++ Q ++ + G + Q +V + Sbjct: 217 GVAVEEGRKAAQSDPNCFFIDDENSRTLFLGYSVAGQRLKAQFAQQGRIVDADNPLFVYL 276 Query: 183 PVGGGGMVAGIAITIK-TLKPSVKVYAAEPSNADDCYQSKLKG---ELTPNLHPPE--TI 236 P G GG G+A +K V + AEP+++ G +++ + T Sbjct: 277 PCGVGGGPGGVAFGLKLAFGDHVHCFFAEPTHSPCMLLGVHTGLHDQISVQDIGIDNLTA 336 Query: 237 ADGVKSSIGLNTWPIIRD-LVDDVFTVTEDEIKYATQLVWERMKLLIEPTAGVGLAA 292 ADG+ + L+D +T+++ + + + + +EP+A G+A Sbjct: 337 ADGLAVGRASGFVGRAMERLLDGFYTLSDQTMYDMLGWLAQEEGIRLEPSALAGMAG 393 >1J0B-A nrPDB Length = 325 Score = 72.8 bits (177), Expect = 2e-13, Method: Composition-based stats. Identities = 52/304 (17%), Positives = 106/304 (34%), Gaps = 29/304 (9%) Query: 26 TPVLTSSILNQIAGRNLFFKCELFQK--TGSFKIRGALNAIRGLIPDTLEGKPKAVVTHS 83 TP+ +++ G +++ K + G KIR + L+ D L V+T Sbjct: 22 TPIQYLPNISREIGADVYIKRDDLTGLGIGGNKIR----KLEYLLGDALSKGADVVITVG 77 Query: 84 S--GNHGQALTYAAKLEGIPAYIVVPQTAPNCKKLAI-QAYGASIVYSEPSD-----ESR 135 + NH AAK G+ A +V+ + + G + D + Sbjct: 78 AVHSNHAFVTGLAAKKLGLDAILVLRGKEELKGNYLLDKIMGIETRVYDAKDSFELMKYA 137 Query: 136 ENVAQRIIQE--TEGILVHPNQEPAVIAGQGTIALEVLNQVP-LVDALVVPVGGGGMVAG 192 E +A+ + +E ++ P G E+ Q D++VV G GG +AG Sbjct: 138 EEIAEELKREGRKPYVIPPGGASPIGTLGYVRAVGEIATQSEVKFDSIVVAAGSGGTLAG 197 Query: 193 IAITIKTLKPSVKVYAAEPSNADDCYQSKLKGELTPNLHPPETIADGVKSSIGLNTWPII 252 +++ + L ++ + SKL L + V+ + ++ Sbjct: 198 LSLGLSILNEDIRPVGIAVGRFGEVMTSKL-DNLIKEAAELLGVKVEVRPELYDYSFGEY 256 Query: 253 RDLVDDVFTVTEDEIKYATQLVWERMKLLIEPT-AGVGLAAVLSQHFQTVSPEVKNICIV 311 + +V + + V R ++++P G ++ + I + Sbjct: 257 GKITGEVAQI--------IRKVGTREGIILDPVYTGKAFYGLVD--LARKGELGEKILFI 306 Query: 312 LSGG 315 +GG Sbjct: 307 HTGG 310 >3R0X-A nrPDB Length = 448 Score = 70.5 bits (171), Expect = 9e-13, Method: Composition-based stats. Identities = 51/326 (15%), Positives = 99/326 (30%), Gaps = 49/326 (15%) Query: 6 CISFADVEKAHLNIQDSVHLTPVLTSSILNQIAGRNLFFKCELFQKTGSFKIRGA-LNAI 64 + ++ T I G L K +GS K RG + Sbjct: 76 ESDVVAIPAMQKRLEKEYGQT----------INGEMLLKKDSHLAISGSIKARGGIYEVL 125 Query: 65 RGLIPDTLEGK---------------------PKAVVTHSSGNHGQALTYAAKLEGIPAY 103 LE ++ S+GN G ++ + G Sbjct: 126 THAEKLALEAGLLTTDDDYSVLLSPEFKQFFSQYSIAVGSTGNLGLSIGIMSACIGFKVT 185 Query: 104 IVVPQTAPNCKKLAIQAYGASIVYSEPSDESRENVAQRIIQETEGILVHPNQEPAVI-AG 162 + + A KK ++++G ++V E ++ Q ++ + G Sbjct: 186 VHMSADARAWKKAKLRSHGVTVVEYEDDYGVAVEQGRKAAQSDPNCFFIDDENSRTLFLG 245 Query: 163 QGTIALEVLNQVPLVDALV---------VPVGGGGMVAGIAITIK-TLKPSVKVYAAEPS 212 + Q +V +P G GG G+A +K +V + AEP+ Sbjct: 246 YAVAGQRLKAQFAQQGRVVDASHPLFVYLPCGVGGGPGGVAFGLKLAFGDNVHCFFAEPT 305 Query: 213 NADDCYQSKLKGELTPNLHPPETI-----ADGVKSSIGLNTWPIIRD-LVDDVFTVTEDE 266 ++ G I ADG+ + L+D ++T+ + Sbjct: 306 HSPCMLLGVYTGLHDAISVQDIGIDNLTAADGLAVGRASGFVGRAMERLLDGLYTLDDQT 365 Query: 267 IKYATQLVWERMKLLIEPTAGVGLAA 292 + + + + +EP+A G+A Sbjct: 366 MYDMLGWLAQEEGIRLEPSALAGMAG 391 >1RQX-A nrPDB Length = 338 Score = 69.4 bits (168), Expect = 2e-12, Method: Composition-based stats. Identities = 57/338 (16%), Positives = 101/338 (29%), Gaps = 49/338 (14%) Query: 22 SVHLTPVLTSSILNQIAGR--NLFFKCELFQKTGSF---KIRGALNAIRGLIPDTLEGKP 76 + TP+ + L++ G +L+ K E +F K R + LIP+ L Sbjct: 12 TFGPTPIQPLARLSKHLGGKVHLYAKREDCNSGLAFGGNKTR----KLEYLIPEALAQGC 67 Query: 77 KAVVT--HSSGNHGQALTYAAKLEGIPAYIVVPQTAPNC--------KKLAIQAYGASIV 126 +V+ N + + A G+ +V + GA + Sbjct: 68 DTLVSIGGIQSNQTRQVAAVAAHLGMKCVLVQENWVNYSDAVYDRVGNIQMSRILGADVR 127 Query: 127 YSEP--------SDESRENVAQRIIQETEGILVHPNQEPAVIAGQGTIALEVLNQVPLV- 177 S E + + I + P G A EV Q + Sbjct: 128 LVPDGFDIGFRRSWEDALESVRAAGGKPYAIPAGCSDHPLGGLGFVGFAEEVRAQEAELG 187 Query: 178 ---DALVVPVGGGGMVAGIAITIKTLKPSVKVYAAEPSNADDCYQSKLKGELTPNLHPPE 234 D +VV G AG+ + + +V + S + Sbjct: 188 FKFDYVVVCSVTGSTQAGMVVGFAADGRADRVIGVDASAKPAQTR-----------EQIT 236 Query: 235 TIADGVKSSIGLNTWPIIRDLV-DDVFT-----VTEDEIKYATQLVWERMKLLIEPT-AG 287 IA +GL + D+V D+ F + + A +L +L +P G Sbjct: 237 RIARQTAEKVGLERDIMRADVVLDERFAGPEYGLPNEGTLEAIRLCARTEGMLTDPVYEG 296 Query: 288 VGLAAVLSQHFQTVSPEVKNICIVLSGGNVDLTSLSWV 325 + ++ PE + GG L S++ Sbjct: 297 KSMHGMIEMVRNGEFPEGSRVLYAHLGGVPALNGYSFI 334 >6EQN-B nrPDB Length = 425 Score = 63.2 bits (152), Expect = 2e-10, Method: Composition-based stats. Identities = 65/348 (18%), Positives = 120/348 (34%), Gaps = 59/348 (16%) Query: 26 TPVLTSSILNQIAGRNL--FFKCELFQKTGSFKIRGALNAIRGLIPDTLEGKPKAVVTHS 83 TP++ + L + G N+ + K E + TGS KI AL + D + Sbjct: 76 TPIIRAKRLEEYLGNNIKIYLKMESYTYTGSHKINSALAHVYYAKLDNAK---FVTTETG 132 Query: 84 SGNHGQALTYAAKLEGIPAYIVVPQT---APNCKKLAIQAYGASI--------------- 125 +G G ++ A+ L + A+I + +T A +K +Q YGA + Sbjct: 133 AGQWGSSVALASALFRMKAHIFMVRTSYYAKPYRKYMMQMYGAEVHPSPSDLTEFGRQLL 192 Query: 126 ---VYSEPSDESRENVAQRIIQETEGILVHPNQEPAVIAGQGTIALEVLNQVPLV----D 178 S + A + G V + + I + +E Q+ L+ D Sbjct: 193 AKDSNHPGSLGIAISDAVEYAHKNGGKYVVGSVVNSDIMFKTIAGMEAKKQMELIGEDPD 252 Query: 179 ALVVPVGGGGMVAGIAI-----TIKTLKPSVKVYAAEPSNADDCYQSKLK------GELT 227 ++ VGGG A +A +++ K K A+ S + K +L Sbjct: 253 YIIGVVGGGSNYAALAYPFLGDELRSGKVRRKYIASGSSEVPKMTKGVYKYDYPDTAKLL 312 Query: 228 PNL---------HPPETIADGVKSSIGLNTWPIIRDLVDDVFT----VTEDEIKYATQLV 274 P L PP A G++ P + L+ +++E +L Sbjct: 313 PMLKMYTIGSDFVPPPVYAGGLRY---HGVAPTLSLLISKGIVQARDYSQEESFKWAKLF 369 Query: 275 WERMKLLIEP--TAGVGLAAVLSQHFQTVSPEVKNICIVLSGGNVDLT 320 E + P + + + A +++ + + G +DL Sbjct: 370 SELEGYIPAPETSHALPILAEIAEEAKKSGERKTVLVSFSGHGLLDLG 417 >1VB3-A nrPDB Length = 428 Score = 61.3 bits (147), Expect = 6e-10, Method: Composition-based stats. Identities = 49/269 (18%), Positives = 100/269 (37%), Gaps = 27/269 (10%) Query: 51 KTGSFKIRGALNAIRGLIPDTLEGKPKAVVTHSSGNHGQALTYAAKLE-GIPAYIVVPQT 109 T +FK G + L KP ++T +SG+ G A+ +A + I+ P+ Sbjct: 102 PTLAFKDFGGRFMAQML-THIAGDKPVTILTATSGDTGAAVAHAFYGLPNVKVVILYPRG 160 Query: 110 A-PNCKKLAIQAYGASI--VYSEPSDESRENVAQRIIQETE-----GILVHPNQEPAVIA 161 ++ G +I V + ++ + + ++ + E G+ + + + Sbjct: 161 KISPLQEKLFCTLGGNIETVAIDGDFDACQALVKQAFDDEELKVALGLNSANSINISRLL 220 Query: 162 GQGTIALEVLNQVPLVD----ALVVPVGGGGMVAGIAITIKTLKPSVKVYAAEPSNADDC 217 Q E + Q+P + VP G G + + K+L VK + A + D Sbjct: 221 AQICYYFEAVAQLPQETRNQLVVSVPSGNFGDLTA-GLLAKSLGLPVKRFIAATNVNDTV 279 Query: 218 YQSKLKGELTPNLHPPETIADGVKSSIGLNTWPIIRDLVDDVF---------TVTEDEIK 268 + G+ +P T+++ + S N WP + +L V ++ + Sbjct: 280 PRFLHDGQWSPK-ATQATLSNAMDVSQPNN-WPRVEELFRRKIWQLKELGYAAVDDETTQ 337 Query: 269 YATQLVWERMKLLIEPTAGVGLAAVLSQH 297 + + + + EP A V A+ Q Sbjct: 338 QTMREL-KELGYTSEPHAAVAYRALRDQL 365 >3V7N-A nrPDB Length = 487 Score = 39.3 bits (90), Expect = 0.002, Method: Composition-based stats. Identities = 25/144 (17%), Positives = 58/144 (40%), Gaps = 13/144 (9%) Query: 10 ADVEKAHLNIQDSVHLTPVLTSSILNQIAGRNLFFKCELFQ-KTGSFKIRGALNAIRGLI 68 ADV + ++ +TP+ + L G + EL T +FK A+ + L Sbjct: 87 ADVYRHARRGGNAADITPL---TTLGTENGAPVSL-LELSNGPTLAFKD-MAMQLLGNLF 141 Query: 69 PDTLEGKPKA--VVTHSSGNHGQALTYAAK-LEGIPAYIVVP-QTAPNCKKLAIQAYGAS 124 TL + ++ +SG+ G A YA + EG+ +++ P + + + + Sbjct: 142 EYTLAKHGETLNILGATSGDTGSAAEYAMRGKEGVRVFMLSPHKKMSAFQTAQMYSLQDP 201 Query: 125 IVY---SEPSDESRENVAQRIIQE 145 ++ + +++ + + + Sbjct: 202 NIFNLAVNGVFDDCQDIVKAVSND 225 >2VCY-A nrPDB Length = 344 Score = 34.7 bits (78), Expect = 0.059, Method: Composition-based stats. Identities = 24/128 (18%), Positives = 49/128 (38%), Gaps = 13/128 (10%) Query: 60 ALNAIRGLIPDTLEGKPKAVVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPNCKK--LA 117 A + + L+ + S+ GQA+ A G+ VV + P+ +K Sbjct: 142 AYRMLMDF--EQLQPGDSVIQNASNSGVGQAVIQIAAALGLRTINVV-RDRPDIQKLSDR 198 Query: 118 IQAYGASIVYSEPSDESRENVAQRIIQETEGILVHPNQEPAVIAGQGTIALEVLNQVPLV 177 +++ GA V +E E + + ++ + P + G+ + E+L Q+ Sbjct: 199 LKSLGAEHVITE------EELRRPEMKNFFKDMPQPRLALNCVGGKSST--ELLRQLARG 250 Query: 178 DALVVPVG 185 +V G Sbjct: 251 GTMVTYGG 258 >4F4F-A nrPDB Length = 468 Score = 34.3 bits (77), Expect = 0.085, Method: Composition-based stats. Identities = 25/155 (16%), Positives = 47/155 (30%), Gaps = 16/155 (10%) Query: 51 KTGSFKIRGALNAIRGL-IPDTLEGKPKAVVTHSSGNH-GQALTYAAKLEGIPAYIVVPQ 108 T +FK R + G+ +V +SG+ G A+ + +I+ P Sbjct: 112 PTLAFKDVAMQLLARMMDYVLAQRGERATIVGATSGDTGGAAIEAFGGRDNTDIFILFPN 171 Query: 109 TAPNCKKLAIQAYGA----SIVYSEPSDESRENVAQRIIQETEG--ILVHPNQEPAVIA- 161 + + + E + + +N+ + + + E L A Sbjct: 172 GRVSPVQQRQMTSSGFSNVHALSIEGNFDDCQNLVKGMFNDLEFCDALSLSGVNSINWAR 231 Query: 162 ------GQGTIALEVLNQVPLVDALVVPVGGGGMV 190 T AL L + VP G G + Sbjct: 232 IMPQVVYYFTAALS-LGAPDRAVSFTVPTGNFGDI 265 >1KL7-A nrPDB Length = 514 Score = 32.8 bits (73), Expect = 0.24, Method: Composition-based stats. Identities = 47/286 (16%), Positives = 93/286 (32%), Gaps = 32/286 (11%) Query: 6 CISFADVEKAHLNIQDSVHLTPVLTSSILNQIAGRNLFFKCELFQ-KTGSFKIRGALNAI 64 D+ K + S +TP++ + ++ NL ELF T +FK AL + Sbjct: 77 DADLKDLIKRSYSTFRSDEVTPLVQNVTGDKE---NLHI-LELFHGPTYAFKD-VALQFV 131 Query: 65 RGLIPDTL----------EGKPKAVVTHSSGNHGQALTYAAK-LEGIPAYIVVPQTAP-- 111 L L E K VV +SG+ G A Y + + + +I+ P Sbjct: 132 GNLFEYFLQRTNANLPEGEKKQITVVGATSGDTGSAAIYGLRGKKDVSVFILYPTGRISP 191 Query: 112 --NCKKLAIQAYGASIVYSEPSDESRENVAQRIIQETEG------ILVHPNQEPAVIAGQ 163 + + + + ++ +++ + I + E V+ ++A Sbjct: 192 IQEEQMTTVPDENVQTLSVTGTFDNCQDIVKAIFGDKEFNSKHNVGAVNSINWARILAQM 251 Query: 164 GTIALEVLNQVPLVDA----LVVPVGGGGMVAGIAITIKTLKPSVKVYAAEPSNADDCYQ 219 D+ VVP G G + K + ++ A + D + Sbjct: 252 TYYFYSFFQATNGKDSKKVKFVVPSGNFGDILA-GYFAKKMGLPIEKLAIATNENDILDR 310 Query: 220 SKLKGELTPNLHPPETIADGVKSSIGLNTWPIIRDLVDDVFTVTED 265 G + T++ + I N ++ L + +D Sbjct: 311 FLKSGLYERSDKVAATLSPAMDILISSNFERLLWYLAREYLANGDD 356 >4G5X-A nrPDB Length = 279 Score = 32.4 bits (72), Expect = 0.29, Method: Composition-based stats. Identities = 33/230 (14%), Positives = 74/230 (32%), Gaps = 42/230 (18%) Query: 119 QAYGASIVYSEPSDESRENVAQRIIQETE--GILVHPN-------------QEPAVIAGQ 163 + GA ++ + S A ++ E ++ P+ + G Sbjct: 21 EGEGAPLLMIHGNSSSGAIFAPQLEGEIGKKWRVIAPDLPGHGKSTDAIDPDRSYSMEGY 80 Query: 164 GTIALEVLNQVPLVDALVVPVGGGGMVA--GIAITIKTLKPSVKVYAAEPSNADDCYQSK 221 EV+ Q+ + DA+V GG + IA + + + P ++ Q Sbjct: 81 ADAMTEVMQQLGIADAVVFGWSLGGHIGIEMIARYPEMR--GLMITGTPPVAREEVGQGF 138 Query: 222 LKGELT----PNLHPPETIADGVKSSIGLNTWPIIRDLVDDVFTVTEDEIKYATQLVWER 277 G + + +S+ G + D+ T+ A ++++E+ Sbjct: 139 KSGPDMALAGQEIFSERDVESYARSTCGE----PFEASLLDIVARTD---GRARRIMFEK 191 Query: 278 MKLLIEPTAGVGLAAVLSQHFQTVSPEVKNICIVLSGGNVDLTSLSWVKQ 327 T G + + + E + V++G + L +V + Sbjct: 192 FG---SGTGG---------NQRDIVAEAQLPIAVVNGRDEPFVELDFVSK 229 >3X0D-A nrPDB Length = 655 Score = 31.6 bits (70), Expect = 0.51, Method: Composition-based stats. Identities = 30/171 (17%), Positives = 59/171 (34%), Gaps = 10/171 (5%) Query: 138 VAQRIIQETEGILVHPNQ-EPAVIAGQGTIALEVLNQVPLVDALVVPVGGG-GMVAGIAI 195 +AQ + + G ++ +AG T E ++ V+ +G G G+++ +A Sbjct: 32 MAQELARSRFGDMILDFDRNDKFLAGLKTTIAEKKHENTDGKVHVLDIGTGTGLLSLMA- 90 Query: 196 TIKTLKPSVKVYAA-EPSNADDCYQSKLKGELTPNLHPPETIADGVKSSIGLNTWPIIRD 254 + V +P DC + + + S IG + II Sbjct: 91 -AREGADKVTALEVFKPMG--DCARHITSNSPWSDKITVISERSTDVSQIGGSRADIIVA 147 Query: 255 LVDDVFTVTEDE---IKYATQLVWERMKLLIEPTAGVGLAAVLSQHFQTVS 302 V D + E K A + + + ++ T V + V S + + Sbjct: 148 EVFDTELIGEGALRTFKEALERLAKPGCRVVPSTGNVYIVPVESHLLKMFN 198 >1YIQ-A nrPDB Length = 689 Score = 30.5 bits (67), Expect = 1.1, Method: Composition-based stats. Identities = 29/238 (12%), Positives = 69/238 (28%), Gaps = 41/238 (17%) Query: 97 LEGIPAYIVVPQTAPNCKKLAIQAYGASIVYSEPSDESRENVAQRI----------IQET 146 G+ + +P+ A ++A +++ ++ +P + A + + Sbjct: 431 QLGLRTGM-MPEGAEGLLEMA-KSWSGKLIAWDPVK---QQAAWEVPYVTIFNGGTLSTA 485 Query: 147 EGILVHPNQEPAVIAGQGTIALEVLNQVPLVDALVVPV--------------GGGGMVAG 192 ++ + + VIA ++ Q + PV G GG + Sbjct: 486 GNLVFEGSADGRVIAYAADTGEKLWEQPAASGVMAAPVTYSVDGEQYVTFMAGWGGAFST 545 Query: 193 IAITIKTLKPSVKVYAAEPSNADDCYQSKLKGELTPNLHPPET------IADGVKSSIGL 246 A + +P Y+ +L P+T D G Sbjct: 546 FAGALSLRA------GVQPYAQVLTYKLGGTAKLQEPAPRPDTPKPPALSNDTASIEAGA 599 Query: 247 NTWPIIRDLVDDVFTVTEDEIKYATQLVWERMKLLIEPTAGVGLAAVLSQHFQTVSPE 304 + + V+ + +L E+ ++ + G + + +PE Sbjct: 600 KLYDGYCSQCHGIHAVSGGVLPDLRKLTPEKHQMFLGILFGGRVPDGMPSFADAFTPE 657 >2H6E-A nrPDB Length = 344 Score = 30.1 bits (66), Expect = 1.4, Method: Composition-based stats. Identities = 22/135 (16%), Positives = 48/135 (35%), Gaps = 14/135 (10%) Query: 153 PNQEPAVIAGQGTIALEVLNQ-VPLVDALVVPV----GGGGMVAGIAITIKTLKPSVKVY 207 E A +A GT ++ + Q +P + PV G GG+ +K L ++ + Sbjct: 141 SPVEAAPLADAGTTSMGAIRQALPFISKFAEPVVIVNGIGGLAVYTIQILKALMKNITIV 200 Query: 208 AAEPSNADDCYQSKLKGELTPNLHPPETIADGVKSSIGLNTWPIIRDLVDDVFTVTEDEI 267 S + +L + + E++ + + +G + + V +E Sbjct: 201 GISRSKKHRDFALELGADYVSEMKDAESLINKLTDGLGASI---------AIDLVGTEET 251 Query: 268 KYATQLVWERMKLLI 282 Y + + +I Sbjct: 252 TYNLGKLLAQEGAII 266 >4EB7-A nrPDB Length = 382 Score = 30.1 bits (66), Expect = 1.6, Method: Composition-based stats. Identities = 28/146 (19%), Positives = 46/146 (31%), Gaps = 22/146 (15%) Query: 132 DESRENVAQRIIQETEGILVHPNQEPAVIAGQGTIALEVLNQVPLVDALVVPVGGGGM-- 189 S + V +RI++ + P+ + G A E + + A +V GGGG Sbjct: 6 YTSAKPVDERILEAMLPYMTESFGNPSSVHSYGFKAREAVQEAREKVAKLVN-GGGGTVV 64 Query: 190 ------------VAGIAITIKTLKPSVKVYAAEPSNADDCYQSKLKGELTPNLHPPETIA 237 + G A+ + V A E L E I Sbjct: 65 FTSGATEANNLAIIGYAMRNARKGKHILVSAVE-----HMSVINPAKFLQKQGFEVEYIP 119 Query: 238 DGVKSSIGLNTWPIIRDLVDDVFTVT 263 G + ++ I + L DD V+ Sbjct: 120 VGKYGEVDVSF--IDQKLRDDTILVS 143 >4REV-A nrPDB Length = 164 Score = 29.7 bits (65), Expect = 1.6, Method: Composition-based stats. Identities = 16/103 (15%), Positives = 34/103 (33%), Gaps = 22/103 (21%) Query: 102 AYIVVPQTAPNCKKLAIQAYGASIVYSEPSDESRENVAQRIIQETEGILVHPNQEPAV-- 159 A + P+ K +G IV+ +P S +++ + + +G ++ + Sbjct: 34 AIVAAPEGVSLTKLAPQSHFGNIIVFDDPITLSH-SLSSKQVGRAQGFYIYDTKNTYTSW 92 Query: 160 ---------IAGQGTI----ALEVLNQVPLVDALVVPVGGGGM 189 QGTI A ++ + + GG Sbjct: 93 LSFTFVLNSTHHQGTITFAGADPIVAKTRDISV------TGGT 129 >3OM8-A nrPDB Length = 266 Score = 29.7 bits (65), Expect = 1.6, Method: Composition-based stats. Identities = 25/159 (15%), Positives = 55/159 (34%), Gaps = 14/159 (8%) Query: 157 PAVIAGQGTIALEVLNQVPLVDALVVPVGGGGMVAGIAITIKTLKPSVKVYAAEPSNADD 216 P +A G LE+L+ + + A + + GG + G + + + ++ A + Sbjct: 73 PYTLARLGEDVLELLDALEVRRAHFLGLSLGG-IVGQWLALHAPQRIERLVLANT--SAW 129 Query: 217 CYQSKLKGELTPNLHPPETIADGVKSSIGLNTWPIIRDLVDDVFTVTEDEIKYATQLVWE 276 + E + E +++ +G P + + + V E A + Sbjct: 130 LGPAAQWDERIAAVLQAEDMSETAAGFLGNWFPPALLERAEPVV-----ERFRAMLMATN 184 Query: 277 RMKLLIEPTAGVGLAAVLSQHFQTVSPEVKNICIVLSGG 315 R L AAV + ++ +V++G Sbjct: 185 RHGL------AGSFAAVRDTDLRAQLARIERPTLVIAGA 217 >3NXS-A nrPDB Length = 329 Score = 29.7 bits (65), Expect = 1.7, Method: Composition-based stats. Identities = 19/117 (16%), Positives = 35/117 (29%), Gaps = 12/117 (10%) Query: 176 LVDALVVPVGGGGMVAGIAITIKTL-----KPSVKVYAAEPSN---ADDCYQSKLKGELT 227 DA + P G + G+A + V E ++ + + Sbjct: 117 HPDAYIRPSPTSGTLGGVAKATRETIVLLEAAGYDVILVETVGVGQSEVTVAGMVDTFVF 176 Query: 228 PNLHPPETIADGVKSSIGLNTWPIIRDLVDDVFTVTED----EIKYATQLVWERMKL 280 L G+K + I+ + D V E+ A +L++ R L Sbjct: 177 LTLARTGDQLQGIKKGVLELADVIVVNKADGEHAVEAKAAARELSGAIRLIYPRESL 233 >3NJR-A nrPDB Length = 204 Score = 29.7 bits (65), Expect = 1.8, Method: Composition-based stats. Identities = 26/87 (29%), Positives = 40/87 (45%), Gaps = 11/87 (12%) Query: 122 GASIVYSEPSDESRENVAQRIIQETEGILVHPNQEPAVIAGQGTIALEVLNQVPLVDALV 181 G + EP + EN+ + I +T G+ P + A QGT A L +PL +A+ Sbjct: 77 GGRAITIEPRADRIENIQKNI--DTYGL------SPRMRAVQGT-APAALADLPLPEAVF 127 Query: 182 VPVGGGGMVAGIAITIKTLKPSVKVYA 208 +GGGG A + L P ++ A Sbjct: 128 --IGGGGSQALYDRLWEWLAPGTRIVA 152 >1PFK-A nrPDB Length = 320 Score = 29.3 bits (64), Expect = 2.2, Method: Composition-based stats. Identities = 22/131 (16%), Positives = 41/131 (31%), Gaps = 21/131 (16%) Query: 187 GGMVAGIAITIKTLKPSVKVYAAEPSNADDCYQSKLKGE-------------LTPNLHPP 233 GG G A + +++ A E + G P + P Sbjct: 65 GGTFLGSARFPEFRDENIRAVAIENLKKRGIDALVVIGGDGSYMGAMRLTEMGFPCIGLP 124 Query: 234 ETIA---DGVKSSIGLNTWPIIRDLVDDVFTVTEDEIKYATQLVWERMKLLIEPTAGVGL 290 TI G +IG + + +V+ + + + + V E M + L Sbjct: 125 GTIDNDIKGTDYTIG--FFTALSTVVEAIDRLRDTSSSHQRISVVEVMGRYCGD---LTL 179 Query: 291 AAVLSQHFQTV 301 AA ++ + V Sbjct: 180 AAAIAGGCEFV 190 >5OC1-A nrPDB Length = 565 Score = 29.3 bits (64), Expect = 2.6, Method: Composition-based stats. Identities = 16/57 (28%), Positives = 21/57 (36%), Gaps = 3/57 (5%) Query: 176 LVDALVVPVGGGGMVAGIAITIKTLKPSVKVYAAEPSNADDCYQSKLKGELTPNLHP 232 D +VV G G V +A + P V V E +D+ L P L P Sbjct: 1 DFDYVVVGAGNAGNV--VAARLTE-DPDVSVLVLEAGVSDENVLGAEAPLLAPGLVP 54 >1X1H-A nrPDB Length = 752 Score = 28.9 bits (63), Expect = 3.4, Method: Composition-based stats. Identities = 10/25 (40%), Positives = 13/25 (52%) Query: 81 THSSGNHGQALTYAAKLEGIPAYIV 105 T S G G A + A + G+ A IV Sbjct: 160 TPSIGLTGAARAWQAIVVGVRAVIV 184 >2W37-A nrPDB Length = 359 Score = 28.5 bits (62), Expect = 3.7, Method: Composition-based stats. Identities = 11/55 (20%), Positives = 22/55 (40%), Gaps = 6/55 (10%) Query: 86 NHGQALTYAAKLEGIPAYIVVPQTA--PNCKKLAIQAY----GASIVYSEPSDES 134 N +L + G+ +IV P+ + + + GA +V ++ DE Sbjct: 188 NVANSLLVTGAILGVNIHIVAPKALFPTEETQNIAKGFAEKSGAKLVITDDLDEG 242 >3JSK-A nrPDB Length = 344 Score = 28.5 bits (62), Expect = 3.9, Method: Composition-based stats. Identities = 19/118 (16%), Positives = 45/118 (38%), Gaps = 10/118 (8%) Query: 104 IVVPQTAPNCKKLAIQAYGASIVYSEPSDESRENVAQRIIQETEGILVHPNQEPAVIAGQ 163 ++ PQ+ P + ++A G + P + +++ +++ + + Sbjct: 5 VLEPQSVPTLVNVGLKAVGRN---DAPVERDARGLSKPLLELMPTLGTDAFTFSPIREST 61 Query: 164 GTIA-----LEVLNQVPLVDALVVPVGGGGMVAGIAITIKTLKPSVKVYAAEPSNADD 216 + A L+ D ++V G G+ A A + TL+P +++ E A Sbjct: 62 VSRAMTRRYFADLDAHAETDIVIVGAGSCGLSA--AYVLSTLRPDLRITIVEAGVAPG 117 >4W8I-A nrPDB Length = 551 Score = 28.5 bits (62), Expect = 4.0, Method: Composition-based stats. Identities = 44/237 (18%), Positives = 77/237 (32%), Gaps = 48/237 (20%) Query: 74 GKPKAVVTHSSGNHGQALTYAAKLEGIPAY------IVVPQTAPNCKKLAIQAYGASIVY 127 + ++TH G AA + A IVVP+TA K A + GA ++ Sbjct: 156 KEGYGLLTH-GGTTSIIEAMAAYVIRARAKGIDYPEIVVPETAHAAFKKAAELTGAILIT 214 Query: 128 SEPSDESRENVAQRIIQETEGILVHPNQEPAVIAGQGT--IALEVLNQVPLVDALVVPVG 185 + ++T + P V++ T A+ V + ++ + P+ Sbjct: 215 VP------------VDKKTGAV------NPNVMSSYITRNTAVMVGSAPSFMNGIHDPIS 256 Query: 186 GGGMVAGIAITIKTLKPSVKVYAAEPSNADDCYQSKLKGELTPNLHPPETIADGVKSSIG 245 G +A K +V P + D C L L + P + GV S Sbjct: 257 ELGQLA--------KKKNV------PFHVDACLGGFLTAFLDTSSEPMDFRVPGVTSISA 302 Query: 246 LNTWPIIRDLVDDVFTVTEDEIKYATQL-------VWERMKLLIEPTAGVGLAAVLS 295 V +ED + ++ +L T+G +A V + Sbjct: 303 DLHKYGCCPKGTSVCLFSEDSPALSVYAALNWSGGLYATPGILDGSTSGARVAEVYA 359 >3RP7-A nrPDB Length = 407 Score = 28.5 bits (62), Expect = 4.4, Method: Composition-based stats. Identities = 15/84 (17%), Positives = 27/84 (32%), Gaps = 12/84 (14%) Query: 175 PLVDALVVPVGGGGMVAGIAIT-----------IKTLKPSVKVYAAEPSNADDCYQSKLK 223 + A+V+ G GG+ A +A+ +K +KP + P+ Sbjct: 22 GHMKAIVIGAGIGGLSAAVALKQSGIDCDVYEAVKEIKPVGAAISVWPNGVKCMAHLG-M 80 Query: 224 GELTPNLHPPETIADGVKSSIGLN 247 G++ P G N Sbjct: 81 GDIMETFGGPLRRMAYRDFRSGEN 104 >1WCV-1 nrPDB Length = 257 Score = 28.5 bits (62), Expect = 4.7, Method: Composition-based stats. Identities = 17/97 (17%), Positives = 25/97 (25%), Gaps = 2/97 (2%) Query: 183 PVGGGGMVAGIAITIKTLKPSVKVYAAEPSNADDCYQSKLKGELTPNLHPPETIADGVKS 242 VG +A + L V + +P +L E + V Sbjct: 17 GVGKTTTAINLAAYLARLGKRVLLVDLDPQGNATSGLGVRAERGVYHLLQGEPLEGLVHP 76 Query: 243 SIGLNTWPIIRDLVDDVFTVTEDEIKYATQLVWERMK 279 G + P DLV TV A + Sbjct: 77 VDGFHLLPATPDLVGA--TVELAGAPTALREALRDEG 111 >5Y2D-A nrPDB Length = 465 Score = 28.1 bits (61), Expect = 5.0, Method: Composition-based stats. Identities = 9/45 (20%), Positives = 13/45 (28%), Gaps = 7/45 (15%) Query: 48 LFQKTGSFKIRGALNAIRGLIPDTLEGKPKAVVTHSSGNHGQALT 92 S G L G A+++ + GNHG Sbjct: 205 SINPGNS----GGALI---DSRGGLVGINTAIISKTGGNHGIGFA 242 >5DTE-A nrPDB Length = 311 Score = 28.1 bits (61), Expect = 5.7, Method: Composition-based stats. Identities = 35/187 (18%), Positives = 59/187 (31%), Gaps = 8/187 (4%) Query: 93 YAAKLEGIPAYIVVPQTAPNCKKLAIQAYGASIVYSEPSDESRENVAQRIIQETEGILVH 152 AK + A IV P + +A A I + A+ + + V Sbjct: 80 MIAKK--VDAIIVTPNDSIAFIPAFQKAEKAGIPIIDLDVRLDAKAAEAAGLKFNYVGVD 137 Query: 153 PNQEPAVIAGQGTIALEVLNQVPLVDAL--VVPVGGGGMVAGIAITIKTLKPSVKVYAAE 210 + A +A E + + V L + V G G A+ P +K+ A++ Sbjct: 138 NFNGGYLEA--KNLA-EAIGKKGNVAILEGIPGVDNGEQRKGGALKAFAEYPDIKIVASQ 194 Query: 211 PSNADDCYQSKLKGELTPNLHPPETI-ADGVKSSIGLNTWPIIRDLVDDVFTVTEDEIKY 269 +N + + + I A +IG T L V D I Sbjct: 195 SANWETEQALNVTTNILTANPNINGIFAANDNMAIGAVTAVENAGLAGKVLVSGYDGIPL 254 Query: 270 ATQLVWE 276 A + V + Sbjct: 255 AIEYVKQ 261 >5Y28-A nrPDB Length = 357 Score = 28.1 bits (61), Expect = 5.7, Method: Composition-based stats. Identities = 9/45 (20%), Positives = 13/45 (28%), Gaps = 7/45 (15%) Query: 48 LFQKTGSFKIRGALNAIRGLIPDTLEGKPKAVVTHSSGNHGQALT 92 S G L G A+++ + GNHG Sbjct: 205 SINPGNS----GGALI---DSRGGLVGINTAIISKTGGNHGIGFA 242 >2OTN-A nrPDB Length = 308 Score = 27.8 bits (60), Expect = 7.4, Method: Composition-based stats. Identities = 16/76 (21%), Positives = 31/76 (40%), Gaps = 3/76 (3%) Query: 246 LNTWPIIRDLVD-DVFTVTEDEIKYATQLVWERMKLLIEPTAGVGLAAVLSQHFQTVSPE 304 L T + + V+ + + +E VWER + + AAV++ Sbjct: 208 LETHEMFPERVNVEFIEILNEEEMNFR--VWERGSGVTQACGTGACAAVVASILNGKMER 265 Query: 305 VKNICIVLSGGNVDLT 320 K I + L+GG++ + Sbjct: 266 GKEITVHLAGGDLMIA 281 >6B6X-A nrPDB Length = 637 Score = 27.8 bits (60), Expect = 8.0, Method: Composition-based stats. Identities = 16/76 (21%), Positives = 31/76 (40%) Query: 57 IRGALNAIRGLIPDTLEGKPKAVVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPNCKKL 116 IR + + T GK +V ++ G+ L + G+P + + N + L Sbjct: 475 IRRDIMVLATGCVTTAAGKAGLLVPEAASKAGEGLAAVCRSLGVPPVLHMGSCVDNSRIL 534 Query: 117 AIQAYGASIVYSEPSD 132 + A A+ + + SD Sbjct: 535 QLCALLATTLGVDISD 550 >1QE0-A nrPDB Length = 420 Score = 27.4 bits (59), Expect = 8.3, Method: Composition-based stats. Identities = 11/75 (14%), Positives = 31/75 (41%), Gaps = 3/75 (4%) Query: 127 YSEPSDESRENVAQRIIQETEGILVHPNQEPAVIAG---QGTIALEVLNQVPLVDALVVP 183 ++ +E + +++ + + + ++P ++ G A E++ P D + Sbjct: 223 ITDFLNEESKAYYEQVKAYLDDLGIPYTEDPNLVRGLDYYTHTAFELMMDNPNYDGAITT 282 Query: 184 VGGGGMVAGIAITIK 198 + GGG G+ + Sbjct: 283 LCGGGRYNGLLELLD 297 >3E05-A nrPDB Length = 204 Score = 27.4 bits (59), Expect = 8.4, Method: Composition-based stats. Identities = 12/42 (28%), Positives = 18/42 (42%), Gaps = 1/42 (2%) Query: 167 ALEVLNQVPLVDALVVPVGGGGMVAGIAITIKTLKPSVKVYA 208 A E L+ +P D + + G GGM+ I + S V Sbjct: 99 APEGLDDLPDPDRVFIG-GSGGMLEEIIDAVDRRLKSEGVIV 139 >2DFV-A nrPDB Length = 347 Score = 27.4 bits (59), Expect = 9.8, Method: Composition-based stats. Identities = 24/144 (16%), Positives = 46/144 (31%), Gaps = 18/144 (12%) Query: 120 AYGASIVYSE-PSDESRENVAQRIIQETEGILVHPNQE---------PAVIAGQGTIALE 169 YGA +V + P E + + + G +H + P I G +A E Sbjct: 13 GYGAELVEVDVPKPGPGEVLIKVLATSICGTDLHIYEWNEWAQSRIKPPQIMGHE-VAGE 71 Query: 170 VLNQVPLVDALVVP--VGG-GGMVAGIAITIK----TLKPSVKVYAAEPSNADDCYQSKL 222 V+ P V+ + V V +V G + + + K++ + Y Sbjct: 72 VVEIGPGVEGIEVGDYVSVETHIVCGKCYACRRGQYHVCQNTKIFGVDTDGVFAEYAVVP 131 Query: 223 KGELTPNLHPPETIADGVKSSIGL 246 + N ++ +G Sbjct: 132 AQNIWKNPKSIPPEYATLQEPLGN 155 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.309 0.131 0.325 Lambda K H 0.267 0.0402 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 11,316,035 Number of Sequences: 36641 Number of extensions: 415410 Number of successful extensions: 2088 Number of sequences better than 10.0: 119 Number of HSP's better than 10.0 without gapping: 130 Number of HSP's successfully gapped in prelim test: 61 Number of HSP's that attempted gapping in prelim test: 1648 Number of HSP's gapped (non-prelim): 202 length of query: 333 length of database: 10,336,785 effective HSP length: 98 effective length of query: 235 effective length of database: 6,745,967 effective search space: 1585302245 effective search space used: 1585302245 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 59 (27.4 bits)