BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q70KY3 (623 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 3QPK-A nrPDB 1150 0.0 3PPS-A nrPDB 898 0.0 6F5K-A nrPDB 886 0.0 3SQR-A nrPDB 368 e-102 5LM8-A nrPDB 331 6e-91 3X1B-A nrPDB 210 1e-54 2XYB-A nrPDB 208 6e-54 5NQ8-A nrPDB 203 2e-52 1KYA-A nrPDB 202 4e-52 3V9C-A nrPDB 201 6e-52 5NQ7-A nrPDB 201 6e-52 1HFU-A nrPDB 194 9e-50 2HZH-A nrPDB 194 1e-49 1V10-A nrPDB 192 3e-49 4A2F-A nrPDB 192 4e-49 2H5U-A nrPDB 189 4e-48 5MIA-A nrPDB 187 9e-48 3KW7-A nrPDB 187 1e-47 5EHF-A nrPDB 186 4e-47 2QT6-A nrPDB 185 4e-47 1GYC-A nrPDB 185 6e-47 4JHU-A nrPDB 182 3e-46 3T6Z-A nrPDB 180 2e-45 5Z1X-A nrPDB 180 2e-45 1ZPU-A nrPDB 152 4e-37 1ASO-A nrPDB 142 4e-34 4F7K-A nrPDB 97 3e-20 4E9V-A nrPDB 86 4e-17 5B7E-A nrPDB 71 1e-12 2YXV-A nrPDB 70 3e-12 3AW5-A nrPDB 65 8e-11 6EVG-A nrPDB 64 2e-10 3G5W-A nrPDB 57 2e-08 5ZLM-A nrPDB 57 3e-08 2YAP-A nrPDB 54 2e-07 3ZX1-A nrPDB 53 5e-07 3GDC-A nrPDB 46 5e-05 3GYR-A nrPDB 39 0.005 3T9W-A nrPDB 39 0.008 2UXV-A nrPDB 38 0.015 2VMJ-A nrPDB 37 0.022 4NB7-A nrPDB 34 0.16 4GXF-A nrPDB 34 0.20 4WTQ-A nrPDB 33 0.34 5TB7-A nrPDB 33 0.40 4N8U-A nrPDB 33 0.42 5LHL-A nrPDB 33 0.51 3TBB-A nrPDB 32 0.67 6IQY-A nrPDB 32 0.81 2ZOO-A nrPDB 32 1.2 5AKR-A nrPDB 31 1.6 1NDS-A nrPDB 31 1.8 2Y1A-A nrPDB 31 1.9 4KNS-A nrPDB 31 2.0 3X1F-A nrPDB 30 2.7 3WIA-A nrPDB 30 3.2 1SDD-A nrPDB 30 3.9 1Z01-A nrPDB 29 5.0 1N70-A nrPDB 29 5.0 1AS8-A nrPDB 29 5.7 >3QPK-A nrPDB Length = 559 Score = 1150 bits (2976), Expect = 0.0, Method: Compositional matrix adjust. Identities = 559/559 (100%), Positives = 559/559 (100%) Query: 51 EPTCNTPSNRACWSDGFDINTDYEVSTPDTGVTQSYVFNLTEVDNWMGPDGVVKEKVMLI 110 EPTCNTPSNRACWSDGFDINTDYEVSTPDTGVTQSYVFNLTEVDNWMGPDGVVKEKVMLI Sbjct: 1 EPTCNTPSNRACWSDGFDINTDYEVSTPDTGVTQSYVFNLTEVDNWMGPDGVVKEKVMLI 60 Query: 111 NGNIMGPNIVANWGDTVEVTVINNLVTNGTSIHWHGIHQKDTNLHDGANGVTECPIPPKG 170 NGNIMGPNIVANWGDTVEVTVINNLVTNGTSIHWHGIHQKDTNLHDGANGVTECPIPPKG Sbjct: 61 NGNIMGPNIVANWGDTVEVTVINNLVTNGTSIHWHGIHQKDTNLHDGANGVTECPIPPKG 120 Query: 171 GQRTYRWRARQYGTSWYHSHFSAQYGNGVVGTIQINGPASLPYDIDLGVFPITDYYYRAA 230 GQRTYRWRARQYGTSWYHSHFSAQYGNGVVGTIQINGPASLPYDIDLGVFPITDYYYRAA Sbjct: 121 GQRTYRWRARQYGTSWYHSHFSAQYGNGVVGTIQINGPASLPYDIDLGVFPITDYYYRAA 180 Query: 231 DDLVHFTQNNAPPFSDNVLINGTAVNPNTGEGQYANVTLTPGKRHRLRILNTSTENHFQV 290 DDLVHFTQNNAPPFSDNVLINGTAVNPNTGEGQYANVTLTPGKRHRLRILNTSTENHFQV Sbjct: 181 DDLVHFTQNNAPPFSDNVLINGTAVNPNTGEGQYANVTLTPGKRHRLRILNTSTENHFQV 240 Query: 291 SLVNHTMTVIAADMVPVNAMTVDSLFLAVGQRYDVVIDASRAPDNYWFNVTFGGQAACGG 350 SLVNHTMTVIAADMVPVNAMTVDSLFLAVGQRYDVVIDASRAPDNYWFNVTFGGQAACGG Sbjct: 241 SLVNHTMTVIAADMVPVNAMTVDSLFLAVGQRYDVVIDASRAPDNYWFNVTFGGQAACGG 300 Query: 351 SLNPHPAAIFHYAGAPGGLPTDEGTPPVDHQCLDTLDVRPVVPRSVPVNSFVKRPDNTLP 410 SLNPHPAAIFHYAGAPGGLPTDEGTPPVDHQCLDTLDVRPVVPRSVPVNSFVKRPDNTLP Sbjct: 301 SLNPHPAAIFHYAGAPGGLPTDEGTPPVDHQCLDTLDVRPVVPRSVPVNSFVKRPDNTLP 360 Query: 411 VALDLTGTPLFVWKVNGSDINVDWGKPIIDYILTGNTSYPVSDNIVQVDAVDQWTYWLIE 470 VALDLTGTPLFVWKVNGSDINVDWGKPIIDYILTGNTSYPVSDNIVQVDAVDQWTYWLIE Sbjct: 361 VALDLTGTPLFVWKVNGSDINVDWGKPIIDYILTGNTSYPVSDNIVQVDAVDQWTYWLIE 420 Query: 471 NDPEGPFSLPHPMHLHGHDFLVLGRSPDVPAASQQRFVFDPAVDLARLNGDNPPRRDTTM 530 NDPEGPFSLPHPMHLHGHDFLVLGRSPDVPAASQQRFVFDPAVDLARLNGDNPPRRDTTM Sbjct: 421 NDPEGPFSLPHPMHLHGHDFLVLGRSPDVPAASQQRFVFDPAVDLARLNGDNPPRRDTTM 480 Query: 531 LPAGGWLLLAFRTDNPGAWLFHCHIAWHVSGGLSVDFLERPADLRQRISQEDEDDFNRVC 590 LPAGGWLLLAFRTDNPGAWLFHCHIAWHVSGGLSVDFLERPADLRQRISQEDEDDFNRVC Sbjct: 481 LPAGGWLLLAFRTDNPGAWLFHCHIAWHVSGGLSVDFLERPADLRQRISQEDEDDFNRVC 540 Query: 591 DEWRAYWPTNPYPKIDSGL 609 DEWRAYWPTNPYPKIDSGL Sbjct: 541 DEWRAYWPTNPYPKIDSGL 559 >3PPS-A nrPDB Length = 604 Score = 898 bits (2320), Expect = 0.0, Method: Compositional matrix adjust. Identities = 446/614 (72%), Positives = 505/614 (82%), Gaps = 15/614 (2%) Query: 1 MKTFTSALALVVGMLAPGAVVAAPPSTPAQRDLVELREARQEGGKDLRPREPTCNTPSNR 60 MK++ +A+AL+VG+L+P A A P + QRD++++ EARQ G PTCNTPSNR Sbjct: 1 MKSWAAAVALMVGILSPHAAAAPPANP-VQRDMLQVLEARQSG--------PTCNTPSNR 51 Query: 61 ACWSDGFDINTDYEVSTPDTGVTQSYVFNLTEVDNWMGPDGVVKEKVMLINGNIMGPNIV 120 ACW++GFDINTDYEVSTP+TG T +Y LTE +NW+GPDGV+K VML+N I+GP I Sbjct: 52 ACWTNGFDINTDYEVSTPNTGRTVAYQLTLTEKENWIGPDGVLKNVVMLVNDKIIGPTIR 111 Query: 121 ANWGDTVEVTVINNLVTNGTSIHWHGIHQKDTNLHDGANGVTECPIPPKGGQRTYRWRAR 180 ANWGD +EVTVINNL TNGTS+HWHG+ Q +DGANGVTECPIPPKGG++TY++RA Sbjct: 112 ANWGDNIEVTVINNLKTNGTSMHWHGLRQLGNVFNDGANGVTECPIPPKGGRKTYKFRAT 171 Query: 181 QYGTSWYHSHFSAQYGNGVVGTIQINGPASLPYDIDLGVFPITDYYYRAADDLVHFTQNN 240 QYGTSWYHSHFSAQYGNGVVGTIQI+GPASLPYDIDLGVFP+ DYYYR+AD+LVHFTQ+N Sbjct: 172 QYGTSWYHSHFSAQYGNGVVGTIQIDGPASLPYDIDLGVFPLMDYYYRSADELVHFTQSN 231 Query: 241 APPFSDNVLINGTAVNPNTGEGQYANVTLTPGKRHRLRILNTSTENHFQVSLVNHTMTVI 300 P SDNVL NGTA +P TG GQ+ NVTLTPGKRHRLRI+NTST+NHFQVSLV H MTVI Sbjct: 232 GAPPSDNVLFNGTARHPETGAGQWYNVTLTPGKRHRLRIINTSTDNHFQVSLVGHNMTVI 291 Query: 301 AADMVPVNAMTVDSLFLAVGQRYDVVIDASRAPDNYWFNVTFGGQAACGGSLNPHPAAIF 360 A DMVPVNA TV SLFLAVGQRYDV IDA+ NYWFNVTF G CG S N PAAIF Sbjct: 292 ATDMVPVNAFTVSSLFLAVGQRYDVTIDANSPVGNYWFNVTF-GDGLCGSSNNKFPAAIF 350 Query: 361 HYAGAPGGLPTDEGTPPVDHQCLDTLDVRPVVPRSVPVNSFVKRPDNTLPVALDLTGTPL 420 Y GAP LPTD+G P +H CLD L++ PVV RS PVN+FVKRP NTL V LD+ GTPL Sbjct: 351 RYQGAPATLPTDQGLPVPNHMCLDNLNLTPVVTRSAPVNNFVKRPSNTLGVTLDIGGTPL 410 Query: 421 FVWKVNGSDINVDWGKPIIDYILTGNTSYPVSDNIVQVDAVDQWTYWLIENDPEGPF-SL 479 FVWKVNGS INVDWGKPI+DY+++GNTSYPVSDNIVQVDAVDQWTYWLIENDP P SL Sbjct: 411 FVWKVNGSAINVDWGKPILDYVMSGNTSYPVSDNIVQVDAVDQWTYWLIENDPTNPIVSL 470 Query: 480 PHPMHLHGHDFLVLGRSPDVPAASQQRFVFDPAVDLARLNGDNPPRRDTTMLPAGGWLLL 539 PHPMHLHGHDFLVLGRSPD ++ R +FDPA DL RL G+NP RRD TMLPAGGWLLL Sbjct: 471 PHPMHLHGHDFLVLGRSPDELPSAGVRHIFDPAKDLPRLKGNNPVRRDVTMLPAGGWLLL 530 Query: 540 AFRTDNPGAWLFHCHIAWHVSGGLSVDFLERPADLRQRIS----QEDEDDFNRVCDEWRA 595 AF+TDNPGAWLFHCHIAWHVSGGLSVDFLERP DLR +++ + D DDFNRVC EW A Sbjct: 531 AFKTDNPGAWLFHCHIAWHVSGGLSVDFLERPNDLRTQLNSNAKRADRDDFNRVCREWNA 590 Query: 596 YWPTNPYPKIDSGL 609 YWPTNP+PKIDSGL Sbjct: 591 YWPTNPFPKIDSGL 604 >6F5K-A nrPDB Length = 559 Score = 886 bits (2290), Expect = 0.0, Method: Compositional matrix adjust. Identities = 421/559 (75%), Positives = 477/559 (85%) Query: 51 EPTCNTPSNRACWSDGFDINTDYEVSTPDTGVTQSYVFNLTEVDNWMGPDGVVKEKVMLI 110 + +CNTPSNRACW+DG+DINTDYEV +PDTGV + Y LTEVDNW GPDGVVKEKVML+ Sbjct: 1 QQSCNTPSNRACWTDGYDINTDYEVDSPDTGVVRPYTLTLTEVDNWTGPDGVVKEKVMLV 60 Query: 111 NGNIMGPNIVANWGDTVEVTVINNLVTNGTSIHWHGIHQKDTNLHDGANGVTECPIPPKG 170 N +I+GP I A+WGDT++VTVINNL TNGTSIHWHG+HQK TNLHDGANG+TECPIPPKG Sbjct: 61 NNSIIGPTIFADWGDTIQVTVINNLETNGTSIHWHGLHQKGTNLHDGANGITECPIPPKG 120 Query: 171 GQRTYRWRARQYGTSWYHSHFSAQYGNGVVGTIQINGPASLPYDIDLGVFPITDYYYRAA 230 G++ YR++A+QYGTSWYHSHFSAQYGNGVVG IQINGPASLPYD DLGVFPI+DYYY +A Sbjct: 121 GRKVYRFKAQQYGTSWYHSHFSAQYGNGVVGAIQINGPASLPYDTDLGVFPISDYYYSSA 180 Query: 231 DDLVHFTQNNAPPFSDNVLINGTAVNPNTGEGQYANVTLTPGKRHRLRILNTSTENHFQV 290 D+LV T+N+ PFSDNVL NGTA +P TGEG+YANVTLTPG+RHRLR++NTS ENHFQV Sbjct: 181 DELVELTKNSGAPFSDNVLFNGTAKHPETGEGEYANVTLTPGRRHRLRLINTSVENHFQV 240 Query: 291 SLVNHTMTVIAADMVPVNAMTVDSLFLAVGQRYDVVIDASRAPDNYWFNVTFGGQAACGG 350 SLVNHTMT+IAADMVPVNAMTVDSLFL VGQRYDVVI+ASR P NYWFNVTFGG CGG Sbjct: 241 SLVNHTMTIIAADMVPVNAMTVDSLFLGVGQRYDVVIEASRTPGNYWFNVTFGGGLLCGG 300 Query: 351 SLNPHPAAIFHYAGAPGGLPTDEGTPPVDHQCLDTLDVRPVVPRSVPVNSFVKRPDNTLP 410 S NP+PAAIFHYAGAPGG PTDEG PVDH CLD +++PVV R VP++ F KRPDNTL Sbjct: 301 SRNPYPAAIFHYAGAPGGPPTDEGKAPVDHNCLDLPNLKPVVARDVPLSGFAKRPDNTLD 360 Query: 411 VALDLTGTPLFVWKVNGSDINVDWGKPIIDYILTGNTSYPVSDNIVQVDAVDQWTYWLIE 470 V LD TGTPLFVWKVNGS IN+DWG+P++DY+LT NTS+P NIV+V+ DQW+YWLIE Sbjct: 361 VTLDTTGTPLFVWKVNGSAINIDWGRPVVDYVLTQNTSFPPGYNIVEVNGADQWSYWLIE 420 Query: 471 NDPEGPFSLPHPMHLHGHDFLVLGRSPDVPAASQQRFVFDPAVDLARLNGDNPPRRDTTM 530 NDP PF+LPHPMHLHGHDF VLGRSPD AS +R VFDPA D L+G NP RRD TM Sbjct: 421 NDPGAPFTLPHPMHLHGHDFYVLGRSPDESPASNERHVFDPARDAGLLSGANPVRRDVTM 480 Query: 531 LPAGGWLLLAFRTDNPGAWLFHCHIAWHVSGGLSVDFLERPADLRQRISQEDEDDFNRVC 590 LPA GW++LAFR DNPGAWLFHCHIAWHVSGGL V +LER DLR +S D DD +R+C Sbjct: 481 LPAFGWVVLAFRADNPGAWLFHCHIAWHVSGGLGVVYLERADDLRGAVSDADADDLDRLC 540 Query: 591 DEWRAYWPTNPYPKIDSGL 609 +WR YWPTNPYPK DSGL Sbjct: 541 ADWRRYWPTNPYPKSDSGL 559 >3SQR-A nrPDB Length = 580 Score = 368 bits (945), Expect = e-102, Method: Compositional matrix adjust. Identities = 220/578 (38%), Positives = 324/578 (56%), Gaps = 41/578 (7%) Query: 47 LRPREPT----CNTPSNRACWSDGFDINTDYEVSTPDTGVTQSYVFNLTEVDNWMGPDGV 102 L PR+ T N+ ++R+CW + + I+T++ TP TGVT+ Y ++ ++ + PDG Sbjct: 29 LTPRQNTTASCANSATSRSCWGE-YSIDTNWYDVTP-TGVTREYWLSVE--NSTITPDGY 84 Query: 103 VKEKVMLINGNIMGPNIVANWGDTVEVTVINNLVTNGTSIHWHGIHQKDTNLHDGANGVT 162 + M NG + GP I+A+WGD + + V NNL NGTSIHWHGI Q + +DG GVT Sbjct: 85 TR-SAMTFNGTVPGPAIIADWGDNLIIHVTNNLEHNGTSIHWHGIRQLGSLEYDGVPGVT 143 Query: 163 ECPIPPKGGQRTYRWRARQYGTSWYHSHFSAQYGNGVVGTIQINGPASLPYDIDLGVFPI 222 +CPI P G TY+++ QYGT+WYHSHFS QYG+G+ G + INGPA+ YD D+GV + Sbjct: 144 QCPIAP-GDTLTYKFQVTQYGTTWYHSHFSLQYGDGLFGPLIINGPATADYDEDVGVIFL 202 Query: 223 TDYYYRAADDLVHFTQNNAPPFSDNVLINGT-------AVNPNT-GEGQYANVTLTPGKR 274 D+ + + ++ + APP +N L+NGT + +PN G G+ +T G + Sbjct: 203 QDWAHESVFEIWDTARLGAPPALENTLMNGTNTFDCSASTDPNCVGGGKKFELTFVEGTK 262 Query: 275 HRLRILNTSTENHFQVSLVNHTMTVIAADMVPVNAMTVDSLFLAVGQRYDVVIDASRAPD 334 +RLR++N ++HF+ ++ NHT+TVIA D+VP+ T D+L + +GQRYDV+++A+ A D Sbjct: 263 YRLRLINVGIDSHFEFAIDNHTLTVIANDLVPIVPYTTDTLLIGIGQRYDVIVEANAAAD 322 Query: 335 NYWFNVTFGGQAACGGSLNPHPAAIFHYAGAPGGLPTDEGTPPVDHQCLDTLDVRPVVPR 394 NYW +G + + I Y + PT GT P C D V +VP Sbjct: 323 NYWIRGNWGTTCSTNNEA-ANATGILRYDSSSIANPTSVGTTP-RGTCEDE-PVASLVPH 379 Query: 395 SVPVNSFVKRPDNTLPVALDLTGTPLFVWKVNGSDINVDWGKPIIDYILTGNTSYPVSDN 454 D + A T F W +N S + +DW P I T +P N Sbjct: 380 LALDVGGYSLVDEQVSSAF----TNYFTWTINSSSLLLDWSSPTTLKIFNNETIFPTEYN 435 Query: 455 IV---QVDAVDQWTYWLIENDPEGPFSLPHPMHLHGHDFLVLGRSPDVPAASQQRFVFDP 511 +V Q +A ++W ++IE D G F + HP+HLHGHDF ++ + D VF+ Sbjct: 436 VVALEQTNANEEWVVYVIE-DLTG-FGIWHPIHLHGHDFFIVAQETD---------VFNS 484 Query: 512 AVDLARLNGDNPPRRDTTMLPAGGWLLLAFRTDNPGAWLFHCHIAWHVSGGLSVDFLERP 571 A+ N NPPRRD LP G+L +AF+ DNPG+WL HCHIAWH S GL++ F+E Sbjct: 485 DESPAKFNLVNPPRRDVAALPGNGYLAIAFKLDNPGSWLLHCHIAWHASEGLAMQFVESQ 544 Query: 572 ADLRQRISQEDEDDFNRVCDEWRAYWPTNPYPKIDSGL 609 + + +++ D F C W AY PT + + DSG+ Sbjct: 545 SSIAVKMT--DTAIFEDTCANWNAYTPTQLFAEDDSGI 580 >5LM8-A nrPDB Length = 549 Score = 331 bits (848), Expect = 6e-91, Method: Compositional matrix adjust. Identities = 200/561 (35%), Positives = 297/561 (52%), Gaps = 56/561 (9%) Query: 66 GFDINTDYEVSTPDTGVTQSYVFNLTEVDNWMGPDGVVKEKVMLINGNIMGPNIVANWGD 125 G+DINT+Y + P T V + Y F++ V+ DGV + V+L+NG GP I ANWGD Sbjct: 6 GYDINTNYYETIPQTNVVREYWFDI--VNTTAALDGV-ERPVLLVNGQFPGPTIEANWGD 62 Query: 126 TVEVTVINNLVTNGTSIHWHGIHQKDTNLHDGANGVTECPIPPKGGQRTYRWRARQYGTS 185 TV+V V N + NGT+IH+HGI Q N DG +T+CP+PP TY WRA +YG+S Sbjct: 63 TVKVHVTNRMENNGTAIHFHGIRQLYNNQMDGVAALTQCPVPPNSS-YTYVWRAEEYGSS 121 Query: 186 WYHSHFSAQYGNGVVGTIQINGPASLPYDIDLGVFPITDYYYRAADDLVH-FTQNNAPPF 244 WYHSHFS Q GV G I I+GP++ YD DLG+ + D+ ++ D++ ++ PP Sbjct: 122 WYHSHFSLQAWEGVFGGILIHGPSTAEYDHDLGMVFLNDWSHQTVDEMYQSVLESQNPPH 181 Query: 245 SDNVLINGTAV---NPNTGEGQYANVTLTPGKRHRLRILNTSTENHFQVSLVNHTMTVIA 301 LING+ + N G+ PG+R+RLR++N + HF+ S+ NH +TVIA Sbjct: 182 FQTGLINGSNIWVTADNQTVGRRFQTEFVPGQRYRLRLVNAAMHTHFRFSIDNHDLTVIA 241 Query: 302 ADMVPVNAMTVDSLFLAVGQRYDVVIDASRAPDNYWFNVTFGGQAACGGSLNP-HPAAIF 360 +D VP+ T +++ + +GQRYD+++ A++APDNYW Q+ C + N + + Sbjct: 242 SDFVPIVPFTTNNVPIGMGQRYDIIVTANQAPDNYWIRAI--PQSFCSDNANSDNIKGVL 299 Query: 361 HYAGA-----PGGLPTDEGTPPVDHQCLD-TLD-VRPVVPRSVPVNSFVKRPDNTLPVAL 413 HY GA P D G D QCLD +LD + P + + + + Sbjct: 300 HYEGAADNSDPTSTKWDYGD---DIQCLDFSLDELVPWLALDADIGGAQMAESD-----V 351 Query: 414 DLT---GTPLFVWKVNGSDINVDWGKPIIDYILT--GNTSYPVSDNIVQVDAVDQWTYWL 468 D T PL++W + G+ +N+ W P + + S +++ ++WT + Sbjct: 352 DFTPFGDVPLYLWTMGGNALNISWKDPTLQQTFEDPDKMDWKASQGVIEAAIPNKWTVLV 411 Query: 469 IENDPEGPFSLPHPMHLHGHDFLVLGRSPDVPAASQQRFVFDPAVDLARLNGDNPPRRDT 528 ++ D +PHP+HLHGHDF +L +Q F+P L NPPRRDT Sbjct: 412 VQTD----LPVPHPIHLHGHDFYLL---------AQGFGQFNPQN--VTLKTHNPPRRDT 456 Query: 529 TMLPA-------GGWLLLAFRTDNPGAWLFHCHIAWHVSGGLSVDFLERPADLRQRISQE 581 ++ A GG++++ F DNPG WL HCHI +H + G + +ER ++ S Sbjct: 457 ALMTAATPENGGGGYMVIGFPADNPGVWLIHCHIGFHATEGFAQQIVERQSEFNTFFS-- 514 Query: 582 DEDDFNRVCDEWRAYWPTNPY 602 ED CD W Y NPY Sbjct: 515 -EDLLENTCDAWDEYAKVNPY 534 >3X1B-A nrPDB Length = 521 Score = 210 bits (535), Expect = 1e-54, Method: Compositional matrix adjust. Identities = 170/503 (33%), Positives = 239/503 (47%), Gaps = 57/503 (11%) Query: 87 VFNLTEVDNWMGPDGVVKEKVMLINGNIMGPNIVANWGDTVEVTVINNL----VTNGTSI 142 V NL + + PDG ++ V+ +NG GP IV N GD + VI+ L + TSI Sbjct: 26 VANLKIGNAAVSPDGYTRDAVV-VNGATPGPLIVGNKGDNFRLNVIDELTNHTMLKSTSI 84 Query: 143 HWHGIHQKDTNLHDGANGVTECPIPPKGGQRTYRWRAR-QYGTSWYHSHFSAQYGNGVVG 201 HWHG Q TN DG V +CPI G +Y ++A+ Q GT WYHSH S QY +G+ G Sbjct: 85 HWHGFFQHGTNWADGGAFVNQCPIS-SGHSFSYNFQAKDQAGTFWYHSHLSTQYCDGLRG 143 Query: 202 TIQI---NGPASLPYDID--LGVFPITDYYYRAADDLVHFTQNNAPPFSDNVLINGTAVN 256 + P YD+D V + D+Y+ AA F P SD+ LING + Sbjct: 144 PFVVYDPKDPHKKLYDVDNESTVITLEDWYHTAARLGPRF-----PLGSDSTLINGLGRS 198 Query: 257 PNTGEGQYANVTLTPGKRHRLRILNTSTENHFQVSLVNHTMTVIAADMVPVNAMTVDSLF 316 T G A + +T GKR+R R+++ S + + S+ H MT+I AD V TVDSL Sbjct: 199 ATTATGDLAVIKVTRGKRYRFRLVSLSCDPFYTFSIDGHNMTIIEADAVNTKPHTVDSLE 258 Query: 317 LAVGQRYDVVIDASRAPDNYWF--NVTFGGQAACGGSLNPHPAAIFHYAGAPGGLPTDEG 374 + GQRY +++A++ DNYW N FG G N +AI Y GA P Sbjct: 259 IFAGQRYSFILNANQPVDNYWVRANPNFGNV----GFTNGINSAILRYDGAAVAEPA-TA 313 Query: 375 TPPVDHQCLDTLDVRPVVPRSVPVNSFVKRPDNTLPVALDLTGTPLFVWKVNGSDINVDW 434 PP L D+ P+V VP + D L + GT F+ + +V Sbjct: 314 IPPASVTPLLETDLHPLVSTPVPGSPVAGGVDKALNFVFNFDGTNFFINDATFTPPSV-- 371 Query: 435 GKPIIDYILTGNTSYP---VSDNIVQVDAVD--QWTYWLIENDPEGPFSLPHPMHLHGHD 489 P++ IL+G + S +++ + A+ + ++ N P +PHP HLHGH Sbjct: 372 --PVLLQILSGAQAAQDLLPSGSVIPLPALSTIELSFPATANAP----GVPHPFHLHGHT 425 Query: 490 FLVLGRSPDVPAASQQRFVFDPAVDLARLNGDNPPRRD--TTMLPAGG-WLLLAFRTDNP 546 F V+ RS A N ++P RD +T PA G + + F TDNP Sbjct: 426 FAVV-RSAGSTA----------------YNYEDPVWRDVVSTGTPAAGDNVTIRFVTDNP 468 Query: 547 GAWLFHCHIAWHVSGGLSVDFLE 569 G W HCHI +H+ G +V F E Sbjct: 469 GPWFLHCHIDFHLEAGFAVVFAE 491 >2XYB-A nrPDB Length = 497 Score = 208 bits (529), Expect = 6e-54, Method: Compositional matrix adjust. Identities = 172/513 (33%), Positives = 243/513 (47%), Gaps = 68/513 (13%) Query: 87 VFNLTEVDNWMGPDGVVKEKVMLINGNIMGPNIVANWGDTVEVTVINNL----VTNGTSI 142 V +LT + + PDG +E V+ +NG P I N GD ++ VI+ L + +SI Sbjct: 5 VADLTLTNAQVSPDGFAREAVV-VNGITPAPLITGNKGDRFQLNVIDQLTNHTMLKTSSI 63 Query: 143 HWHGIHQKDTNLHDGANGVTECPIPPKGGQRTYRWRA-RQYGTSWYHSHFSAQYGNGVVG 201 HWHG Q+ TN DG V +CPI G Y ++ Q GT WYHSH S QY +G+ G Sbjct: 64 HWHGFFQQGTNWADGPAFVNQCPIA-SGHSFLYDFQVPDQAGTFWYHSHLSTQYCDGLRG 122 Query: 202 TIQI---NGPASLPYDIDLG--VFPITDYYYRAADDLVHFTQNNAPPF-SDNVLINGTAV 255 + N P + YDID V + D+Y+ AA F PF SD+ LING Sbjct: 123 PFVVYDPNDPHASLYDIDNDDTVITLADWYHVAAKLGPRF------PFGSDSTLINGLGR 176 Query: 256 NPNTGEGQYANVTLTPGKRHRLRILNTSTENHFQVSLVNHTMTVIAADMVPVNAMTVDSL 315 A + +T GKR+R R+++ S + + S+ NHTMT+I AD + + VDS+ Sbjct: 177 TTGIAPSDLAVIKVTQGKRYRFRLVSLSCDPNHTFSIDNHTMTIIEADSINTQPLEVDSI 236 Query: 316 FLAVGQRYDVVIDASRAPDNYWF--NVTFGGQAACGGSLNPHPAAIFHYAGAPGGLPTDE 373 + QRY V+DAS+ DNYW N FG GG +N +AI Y GAP PT Sbjct: 237 QIFAAQRYSFVLDASQPVDNYWIRANPAFGNTGFAGG-IN---SAILRYDGAPEIEPTSV 292 Query: 374 GTPPVDHQCLDTLDVRPVVPRSVPVNSFVKRPDNTLPVALDLTGTPLFVWKVNGSDINVD 433 T P + L+ +D+ P+ P VP + D L + + GT F+ V Sbjct: 293 QTTPT--KPLNEVDLHPLSPMPVPGSPEPGGVDKPLNLVFNFNGTNFFI----NDHTFVP 346 Query: 434 WGKPIIDYILTGNTSYPVSDNIVQVDAVDQWTYWLIENDPEGPFS---------LPHPMH 484 P++ IL+G + D V + + +++ ++ S PHP H Sbjct: 347 PSVPVLLQILSGAQA--------AQDLVPEGSVFVLPSNSSIEISFPATANAPGFPHPFH 398 Query: 485 LHGHDFLVLGRSPDVPAASQQRFVFDPAVDLARLNGDNPPRRD--TTMLPAGGWLLLAFR 542 LHGH F V+ RS A S + N DNP RD +T P G + + F Sbjct: 399 LHGHAFAVV-RS----AGS------------SVYNYDNPIFRDVVSTGQP-GDNVTIRFE 440 Query: 543 TDNPGAWLFHCHIAWHVSGGLSVDFLERPADLR 575 T+NPG W HCHI +H+ G +V E D + Sbjct: 441 TNNPGPWFLHCHIDFHLDAGFAVVMAEDTPDTK 473 >5NQ8-A nrPDB Length = 518 Score = 203 bits (516), Expect = 2e-52, Method: Compositional matrix adjust. Identities = 172/510 (33%), Positives = 240/510 (47%), Gaps = 66/510 (12%) Query: 87 VFNLTEVDNWMGPDGVVKEKVMLINGNIMGPNIVANWGDTVEVTVINNL----VTNGTSI 142 V +LT + + PDG +E V ++NG P I GD ++ VI+NL + TSI Sbjct: 26 VADLTLTNAAVSPDGFSREAV-VVNGVTPAPLISGQKGDRFQLNVIDNLTNHTMLKTTSI 84 Query: 143 HWHGIHQKDTNLHDGANGVTECPIPPKGGQRTYRWRA-RQYGTSWYHSHFSAQYGNGVVG 201 HWHG Q TN DG V +CPI G Y ++ Q GT WYHSH S QY +G+ G Sbjct: 85 HWHGFFQHGTNWADGPAFVNQCPIA-SGHSFLYDFQVPDQAGTFWYHSHLSTQYCDGLRG 143 Query: 202 TIQI---NGPASLPYDIDLG--VFPITDYYYRAADDLVHFTQNNAPPFSDNVLINGTAVN 256 + N P + YDID V + D+Y+ AA F PP SD LING + Sbjct: 144 PFVVYDPNDPQASLYDIDNDDTVITLADWYHVAAKLGPRF-----PPGSDATLINGLGRS 198 Query: 257 PNTGEGQYANVTLTPGKRHRLRILNTSTENHFQVSLVNHTMTVIAADMVPVNAMTVDSLF 316 P T A + +T GKR+R R+++ S + + S+ HTMT+I AD V + VDS+ Sbjct: 199 PGTTAADLAVIKVTQGKRYRFRLVSLSCDPNHTFSIDGHTMTIIEADSVNTQPLEVDSIQ 258 Query: 317 LAVGQRYDVVIDASRAPDNYWF--NVTFGGQAACGGSLNPHPAAIFHYAGAPGGLPTDEG 374 + QRY V+DAS+ DNYW N +FG GG +N +AI Y GAP Sbjct: 259 IFAAQRYSFVLDASQPVDNYWIRANPSFGNTGFAGG-IN---SAILRYLGAPE--IEPTT 312 Query: 375 TPPVDHQCLDTLDVRPVVPRSVPVNSFVKRPDNTLPVALDLTGTPLFVWKVNGSDINVDW 434 T + L +D+ P+ P +VP D L + + GT F+ + V Sbjct: 313 TQTTPTKPLTEVDLHPLTPMAVPGRPEPGGVDKPLNMVFNFNGTNFFI----NNHSFVPP 368 Query: 435 GKPIIDYILTGNTSYPVSDNIVQVDAVDQWTYWLIENDPEGPFSL---------PHPMHL 485 P++ IL+G + D V + + +++ ++ S PHP HL Sbjct: 369 SVPVLLQILSGAQA--------AQDLVPEGSVYVLPSNSSIEISFPATVNAPGAPHPFHL 420 Query: 486 HGHDFLVLGRSPDVPAASQQRFVFDPAVDLARLNGDNPPRRD--TTMLPAGGWLLLAFRT 543 HGH F V+ RS A S + N DNP RD +T P G + + F+T Sbjct: 421 HGHTFAVV-RS----AGSSE------------YNYDNPIFRDVVSTGTP-GDNVTIRFQT 462 Query: 544 DNPGAWLFHCHIAWHVSGGLSVDFLERPAD 573 NPG W HCHI +H+ G +V E D Sbjct: 463 ANPGPWFLHCHIDFHLDAGFAVVMAEDTPD 492 >1KYA-A nrPDB Length = 499 Score = 202 bits (514), Expect = 4e-52, Method: Compositional matrix adjust. Identities = 172/511 (33%), Positives = 253/511 (49%), Gaps = 64/511 (12%) Query: 87 VFNLTEVDNWMGPDGVVKEKVMLINGNIMGPNIVANWGDTVEVTVINNL----VTNGTSI 142 V +LT + + PDG ++ V ++NG GP I N GD ++ VI+NL + TSI Sbjct: 5 VADLTITNAAVSPDGFSRQAV-VVNGGTPGPLITGNMGDRFQLNVIDNLTNHTMLKSTSI 63 Query: 143 HWHGIHQKDTNLHDGANGVTECPIPPKGGQRTYRWRA-RQYGTSWYHSHFSAQYGNGVVG 201 HWHG QK TN DG + +CPI G Y ++ Q GT WYHSH S QY +G+ G Sbjct: 64 HWHGFFQKGTNWADGPAFINQCPIS-SGHSFLYDFQVPDQAGTFWYHSHLSTQYCDGLRG 122 Query: 202 TIQI---NGPASLPYDIDLG--VFPITDYYYRAADDLVHFTQNNAPPFSDNVLINGTAVN 256 + N PA+ YD+D V + D+Y+ AA F P +D LING + Sbjct: 123 PFVVYDPNDPAADLYDVDNDDTVITLVDWYHVAAKLGPAF-----PLGADATLINGKGRS 177 Query: 257 PNTGEGQYANVTLTPGKRHRLRILNTSTENHFQVSLVNHTMTVIAADMVPVNAMTVDSLF 316 P+T + +++TPGKR+R R+++ S + ++ S+ H MT+I D + + VDS+ Sbjct: 178 PSTTTADLSVISVTPGKRYRFRLVSLSCDPNYTFSIDGHNMTIIETDSINTAPLVVDSIQ 237 Query: 317 LAVGQRYDVVIDASRAPDNYWF--NVTFGGQAACGGSLNPHPAAIFHYAGAPGGLPTDEG 374 + QRY V++A++A DNYW N FG GG +N +AI Y GA PT Sbjct: 238 IFAAQRYSFVLEANQAVDNYWIRANPNFGNVGFTGG-IN---SAILRYDGAAAVEPTTTQ 293 Query: 375 TPPVDHQCLDTLDVRPVVPRSVPVNSFVKRPDNTLPVALDLTGTPLFVWKVNGSDINVDW 434 T L+ +++ P+V +VP + D + +A + GT F+ + + V Sbjct: 294 T--TSTAPLNEVNLHPLVATAVPGSPVAGGVDLAINMAFNFNGTNFFINGASFTPPTV-- 349 Query: 435 GKPIIDYILTGNTSYPVSDNIVQVDAVDQWTYWLIEN-DPEGPF-------SLPHPMHLH 486 P++ I++G + + +++ +V Y L N D E F PHP HLH Sbjct: 350 --PVLLQIISGAQN---AQDLLPSGSV----YSLPSNADIEISFPATAAAPGAPHPFHLH 400 Query: 487 GHDFLVLGRSPDVPAASQQRFVFDPAVDLARLNGDNPPRRD--TTMLPAGG-WLLLAFRT 543 GH F V V +A + N DNP RD +T PA G + + FRT Sbjct: 401 GHAFAV------VRSAGSTVY-----------NYDNPIFRDVVSTGTPAAGDNVTIRFRT 443 Query: 544 DNPGAWLFHCHIAWHVSGGLSVDFLERPADL 574 DNPG W HCHI +H+ G +V F E D+ Sbjct: 444 DNPGPWFLHCHIDFHLEAGFAVVFAEDIPDV 474 >3V9C-A nrPDB Length = 499 Score = 201 bits (512), Expect = 6e-52, Method: Compositional matrix adjust. Identities = 168/513 (32%), Positives = 247/513 (48%), Gaps = 66/513 (12%) Query: 87 VFNLTEVDNWMGPDGVVKEKVMLINGNIMGPNIVANWGDTVEVTVINNL----VTNGTSI 142 V +LT D + PDG ++ V ++NG GP + N GD ++ VI+NL + TSI Sbjct: 5 VADLTITDAAVSPDGFSRQAV-VVNGVTPGPLVAGNIGDRFQLNVIDNLTNHTMLKSTSI 63 Query: 143 HWHGIHQKDTNLHDGANGVTECPIPPKGGQRTYRWRA-RQYGTSWYHSHFSAQYGNGVVG 201 HWHG Q TN DG + +CPI P G Y ++ Q GT WYHSH S QY +G+ G Sbjct: 64 HWHGFFQHGTNWADGPAFINQCPISP-GHSFLYDFQVPDQAGTFWYHSHLSTQYCDGLRG 122 Query: 202 TIQI---NGPASLPYDIDLG--VFPITDYYYRAADDLVHFTQNNAPPFSDNVLINGTAVN 256 + N P + YD+D V + D+Y+ AA F P +D LING Sbjct: 123 PFVVYDPNDPHASRYDVDNDDTVITLADWYHTAAKLGPRF-----PGGADATLINGKGRA 177 Query: 257 PNTGEGQYANVTLTPGKRHRLRILNTSTENHFQVSLVNHTMTVIAADMVPVNAMTVDSLF 316 P+ + + + +T GKR+R R+++ S + S+ H +T+I D V + VDS+ Sbjct: 178 PSDSVAELSVIKVTKGKRYRFRLVSLSCNPNHTFSIDGHNLTIIEVDSVNSQPLEVDSIQ 237 Query: 317 LAVGQRYDVVIDASRAPDNYWF--NVTFGGQAACGGSLNPHPAAIFHYAGAPGGLPTDEG 374 + QRY V+DA++A DNYW N FG GG +N +AI Y GAP PT Sbjct: 238 IFAAQRYSFVLDANQAVDNYWIRANPNFGNVGFDGG-IN---SAILRYDGAPAVEPTTNQ 293 Query: 375 TPPVDHQCLDTLDVRPVVPRSVPVNSFVKRPDNTLPVALDLTGTPLFVWKVNGSDINVDW 434 T V + L+ +D+ P+V VP + D + +A + G+ F +NG+ V Sbjct: 294 TTSV--KPLNEVDLHPLVSTPVPGSPSSGGVDKAINMAFNFNGSNFF---INGASF-VPP 347 Query: 435 GKPIIDYILTGNTSYPVSDNIVQVDAVDQWTYWLIENDPEGPFSL---------PHPMHL 485 P++ IL+G + D + + +++ ++ S PHP HL Sbjct: 348 TVPVLLQILSGAQT--------AQDLLPSGSVYVLPSNASIEISFPATAAAPGAPHPFHL 399 Query: 486 HGHDFLVLGRSPDVPAASQQRFVFDPAVDLARLNGDNPPRRD--TTMLPAGG-WLLLAFR 542 HGH F V V +A + N DNP RD +T PA G + + F Sbjct: 400 HGHTFAV------VRSAGSTVY-----------NYDNPIFRDVVSTGTPAAGDNVTIRFD 442 Query: 543 TDNPGAWLFHCHIAWHVSGGLSVDFLERPADLR 575 T+NPG W HCHI +H+ GG +V E D++ Sbjct: 443 TNNPGPWFLHCHIDFHLEGGFAVVMAEDTPDVK 475 >5NQ7-A nrPDB Length = 518 Score = 201 bits (512), Expect = 6e-52, Method: Compositional matrix adjust. Identities = 173/506 (34%), Positives = 239/506 (47%), Gaps = 58/506 (11%) Query: 87 VFNLTEVDNWMGPDGVVKEKVMLINGNIMGPNIVANWGDTVEVTVINNL----VTNGTSI 142 V +LT + + PDG +E V+ +NG P I GD ++ VI+NL + TSI Sbjct: 26 VADLTLTNAAVSPDGFTREAVV-VNGITPAPLIAGKKGDRFQLNVIDNLTNHTMLKTTSI 84 Query: 143 HWHGIHQKDTNLHDGANGVTECPIPPKGGQRTYRWRA-RQYGTSWYHSHFSAQYGNGVVG 201 HWHG Q TN DG + V +CPI G Y ++ Q GT WYHSH S QY +G+ G Sbjct: 85 HWHGFFQHGTNWADGVSFVNQCPIA-SGHSFLYDFQVPDQAGTFWYHSHLSTQYCDGLRG 143 Query: 202 TIQI---NGPASLPYDIDLG--VFPITDYYYRAADDLVHFTQNNAPPFSDNVLINGTAVN 256 + N P + YDID V + D+Y+ AA F P +D LING Sbjct: 144 PFVVYDPNDPQASLYDIDNDDTVITLADWYHLAAKVGQRF-----PLGADATLINGLGRT 198 Query: 257 PNTGEGQYANVTLTPGKRHRLRILNTSTENHFQVSLVNHTMTVIAADMVPVNAMTVDSLF 316 P T A + +T GKR+R R+++ S + + S+ HTMT+I AD V + VDS+ Sbjct: 199 PGTTSADLAVIKVTQGKRYRFRLVSLSCDPNHTFSIDGHTMTIIEADSVNTQPLEVDSIQ 258 Query: 317 LAVGQRYDVVIDASRAPDNYWF--NVTFGGQAACGGSLNPHPAAIFHYAGAPGGLPTDEG 374 + QRY V+DAS+ DNYW N FG GG +N +AI Y GAP Sbjct: 259 IFAAQRYSFVLDASQPVDNYWIRANPPFGNVGFAGG-IN---SAILRYDGAPE--VEPTT 312 Query: 375 TPPVDHQCLDTLDVRPVVPRSVPVNSFVKRPDNTLPVALDLTGTPLFVWKVNGSDINVDW 434 T + L+ D+ P+ P VP D L + + GT F+ + V Sbjct: 313 TQTTPTKPLNEADLHPLTPMPVPGRPEPGGVDKPLNMVFNFNGTNFFI----NNHSFVPP 368 Query: 435 GKPIIDYILTGNTSYP--VSDNIVQV---DAVDQWTYWLIENDPEGPFSLPHPMHLHGHD 489 P++ IL+G + V + V V +A + ++ N P PHP HLHGH Sbjct: 369 SVPVLLQILSGAQAAQDLVPEGSVYVLPSNASIEISFPATANAPGS----PHPFHLHGHT 424 Query: 490 FLVLGRSPDVPAASQQRFVFDPAVDLARLNGDNPPRRD--TTMLPAGGWLLLAFRTDNPG 547 F V+ RS A S + N DNP RD +T P G + + F+T+NPG Sbjct: 425 FAVV-RS----AGSSE------------YNYDNPVFRDVVSTGTP-GDNVTIRFQTNNPG 466 Query: 548 AWLFHCHIAWHVSGGLSVDFLERPAD 573 W HCHI +H+ G +V E D Sbjct: 467 PWFLHCHIDFHLDAGFAVVMAEDTPD 492 >1HFU-A nrPDB Length = 503 Score = 194 bits (493), Expect = 9e-50, Method: Compositional matrix adjust. Identities = 159/503 (31%), Positives = 236/503 (46%), Gaps = 58/503 (11%) Query: 90 LTEVDNWMGPDGVVKEKVMLINGNIMGPNIVANWGDTVEVTVINNL----VTNGTSIHWH 145 +T + + PDG + + L+NG + GP I D E+ V+N+L + TSIHWH Sbjct: 9 MTLTNANVSPDGFTRAGI-LVNG-VHGPLIRGGKNDNFELNVVNDLDNPTMLRPTSIHWH 66 Query: 146 GIHQKDTNLHDGANGVTECPIPPKGGQRTYRWR-ARQYGTSWYHSHFSAQYGNGVVGTIQ 204 G+ Q+ TN DGA+GV +CPI P G Y++ A GT WYHSHF QY +G+ G + Sbjct: 67 GLFQRGTNWADGADGVNQCPISP-GHAFLYKFTPAGHAGTFWYHSHFGTQYCDGLRGPMV 125 Query: 205 I---NGPASLPYDID--LGVFPITDYYYRAADDLVHFTQNNAPPFSDNVLINGTAVNPNT 259 I N P + YD D + + D+Y+ A + Q A P D LING Sbjct: 126 IYDDNDPHAALYDEDDENTIITLADWYHIPAPSI----QGAAQP--DATLINGKGRYVGG 179 Query: 260 GEGQYANVTLTPGKRHRLRILNTSTENHFQVSLVNHTMTVIAADMVPVNAMTVDSLFLAV 319 + + V + GK++R+R+++ S + ++Q S+ H +T+I D TVD L + Sbjct: 180 PAAELSIVNVEQGKKYRMRLISLSCDPNWQFSIDGHELTIIEVDGELTEPHTVDRLQIFT 239 Query: 320 GQRYDVVIDASRAPDNYWFNV--TFGGQAACGGSLNPHPAAIFHYAGAPGGLPTDEGTPP 377 GQRY V+DA++ DNYW G G N +AI YAGA PT P Sbjct: 240 GQRYSFVLDANQPVDNYWIRAQPNKGRNGLAGTFANGVNSAILRYAGAANADPTTSANP- 298 Query: 378 VDHQCLDTLDVRPVVPRSVPVNSFVKRPDNTLPVALDLTGTPLFVWKVNGSDINVDWGKP 437 + L+ D+ ++ + P D L L +G + +NG+ + P Sbjct: 299 -NPAQLNEADLHALIDPAAPGIPTPGAADVNLRFQLGFSGG---RFTINGT----AYESP 350 Query: 438 IIDYILTGNTSYPVSDNIVQVDAVDQWTYWLIEND------PEGPFSLPHPMHLHGHDFL 491 + +L + +++++ +V Y L N P G PHP HLHGH F Sbjct: 351 SVPTLLQIMSGAQSANDLLPAGSV----YELPRNQVVELVVPAGVLGGPHPFHLHGHAFS 406 Query: 492 VLGRSPDVPAASQQRFVFDPAVDLARLNGDNPPRRDTTMLPA-GGWLLLAFRTDNPGAWL 550 V+ + +S FV NP +RD L G + + F TDNPG W Sbjct: 407 VVRSA----GSSTYNFV-------------NPVKRDVVSLGVTGDEVTIRFVTDNPGPWF 449 Query: 551 FHCHIAWHVSGGLSVDFLERPAD 573 FHCHI +H+ GL++ F E A+ Sbjct: 450 FHCHIEFHLMNGLAIVFAEDMAN 472 >2HZH-A nrPDB Length = 499 Score = 194 bits (492), Expect = 1e-49, Method: Compositional matrix adjust. Identities = 159/511 (31%), Positives = 238/511 (46%), Gaps = 68/511 (13%) Query: 89 NLTEVDNWMGPDGVVKEKVMLINGNIMGPNIVANWGDTVEVTVINNL----VTNGTSIHW 144 NL + + DG ++ V ++NG GP I N GD ++ VINNL + TS+HW Sbjct: 7 NLVVTNAAVAADGHSRDAV-VVNGGTPGPLITGNKGDQFQLNVINNLTNFTMLKSTSVHW 65 Query: 145 HGIHQKDTNLHDGANGVTECPIPPKGGQRTYRWRA-RQYGTSWYHSHFSAQYGNGVVGTI 203 HG QK TN DG V +CPI G Y + Q GT WYHSH S QY +G G Sbjct: 66 HGFFQKGTNWADGPAFVNQCPIA-AGSSFLYDFSTPIQAGTFWYHSHLSTQYCDGDRGPF 124 Query: 204 QI---NGPASLPYDIDL--GVFPITDYYYRAADDLVHFTQNN--APPFSDNVLINGTAVN 256 + N P++ YD+D V +TD+Y+ AA QN P +D LING Sbjct: 125 VVYDPNDPSANLYDVDNLNTVITLTDWYHTAA-------QNGPAKPGGADATLINGQGRG 177 Query: 257 PNTGEGQYANVTLTPGKRHRLRILNTSTENHFQVSLVNHTMTVIAADMVPVNAMTVDSLF 316 P++ A +++T GKR+R R+++ S + ++ S+ H MT+I D + V + V + Sbjct: 178 PSSPSADLAVISVTAGKRYRFRLVSNSCDPNYTFSIDGHQMTIIQVDSINVQPLVVLKIQ 237 Query: 317 LAVGQRYDVVIDASRAPDNYWFNVT-FGGQAACGGSLNPHPAAIFHYAGAPGGLPTDEGT 375 + QRY +++A++A +NYW G +N +AI Y+GA PT T Sbjct: 238 IYAAQRYSFILNANQAVNNYWIRANPNQGNVGFTNGIN---SAILRYSGAAATQPTTSQT 294 Query: 376 PPVDHQCLDTLDVRPVVPRSVPVNSFVKRPDNTLPVALDLTGTPLFVWKVNGSDINVDWG 435 V Q LD ++ P+ +VP + + + A + GT F V+G+ V Sbjct: 295 SSV--QPLDQTNLHPLTATAVPGSPVAGGVNLAINQAFNFNGTNHF---VDGASF-VPPT 348 Query: 436 KPIIDYILTGNTSYPVSDNIVQVDAVDQWTYWLIENDPEGPFSL---------PHPMHLH 486 P++ I++G S D + + + +D S PHP HLH Sbjct: 349 VPVLSQIVSGAQS--------AADLLASGLVYSLPSDANIEISFPATSAAAGGPHPFHLH 400 Query: 487 GHDFLVLGRSPDVPAASQQRFVFDPAVDLARLNGDNPPRRDT--TMLPAGG-WLLLAFRT 543 GH F V V +A + N ++P RDT T PA + + F+T Sbjct: 401 GHAFAV------VRSAGSTTY-----------NYNDPIFRDTVSTGTPAANDNVTIRFKT 443 Query: 544 DNPGAWLFHCHIAWHVSGGLSVDFLERPADL 574 +NPG W HCHI +H+ G +V F + D+ Sbjct: 444 NNPGPWFLHCHIDFHLEAGFAVVFAQDIPDV 474 >1V10-A nrPDB Length = 521 Score = 192 bits (488), Expect = 3e-49, Method: Compositional matrix adjust. Identities = 174/552 (31%), Positives = 250/552 (45%), Gaps = 59/552 (10%) Query: 75 VSTPDTGVTQSYVFNLTEVDNWMGPDGVVKEKVMLINGNIMGPNIVANWGDTVEVTVINN 134 +S + + +L ++ + PDG + G + P I N D ++ VI+ Sbjct: 13 LSLTSLSLAATVALDLHILNANLDPDGTGARSAVTAEGTTIAPLITGNIDDRFQINVIDQ 72 Query: 135 L----VTNGTSIHWHGIHQKDTNLHDGANGVTECPIPPKGGQRTYRWRARQYGTSWYHSH 190 L + TSIHWHG Q T DG V +CPI P Q GT WYHSH Sbjct: 73 LTDANMRRATSIHWHGFFQAGTTEMDGPAFVNQCPIIPNESFVYDFVVPGQAGTYWYHSH 132 Query: 191 FSAQYGNGVVGTIQI---NGPASLPYDIDLG--VFPITDYYYRAADDLVHFTQNNAPPFS 245 S QY +G+ G + N P YD+D V I D+Y+ + ++ N APP Sbjct: 133 LSTQYCDGLRGAFVVYDPNDPHLSLYDVDDASTVITIADWYH-SLSTVLFPNPNKAPPAP 191 Query: 246 DNVLINGTAVN-PNTGEGQYANVTLTPGKRHRLRILNTSTENHFQVSLVNHTMTVIAADM 304 D LING N N GQ A V++ GKR+R RI++TS ++ S+ H MTVI D Sbjct: 192 DTTLINGLGRNSANPSAGQLAVVSVQSGKRYRFRIVSTSCFPNYAFSIDGHRMTVIEVDG 251 Query: 305 VPVNAMTVDSLFLAVGQRYDVVIDASRAPDNYWFNVT-FGGQAACGGSLNPHPAAIFHYA 363 V +TVDSL + GQRY VV++A++A NYW G+ G +N +AIF Y Sbjct: 252 VSHQPLTVDSLTIFAGQRYSVVVEANQAVGNYWIRANPSNGRNGFTGGIN---SAIFRYQ 308 Query: 364 GAPGGLPTDEGTPPVDHQCLDTLDVRPVVPRSVPVNSFVKRPDNTLPVALDLTGTPLFVW 423 GA PT T L+ ++ P++ P N D L + + T + Sbjct: 309 GAAVAEPT---TSQNSGTALNEANLIPLINPGAPGNPVPGGADINLNLRIGRNATTA-DF 364 Query: 424 KVNGSDINVDWGKPIIDYILTGNTSYPVSDNIVQVDAVDQWTYWLIENDPEGPFSLP--- 480 +NG+ + P++ IL+G T+ +D + + +IE S+P Sbjct: 365 TINGAPF-IPPTVPVLLQILSGVTN--PNDLLPGGAVISLPANQVIE------ISIPGGG 415 Query: 481 -HPMHLHGHDFLVLGRSPDVPAASQQRFVFDPAVDLARLNGDNPPRRDTTMLPAGG-WLL 538 HP HLHGH+F V+ P +S +V NP RRD + GG + Sbjct: 416 NHPFHLHGHNFDVV----RTPGSSVYNYV-------------NPVRRDVVSIGGGGDNVT 458 Query: 539 LAFRTDNPGAWLFHCHIAWHVSGGLSVDFLERPADLRQRISQEDEDDFNRVCDEWRAYWP 598 F TDNPG W HCHI WH+ GL+V F E ++ I+ ++ +C ++ A P Sbjct: 459 FRFVTDNPGPWFLHCHIDWHLEAGLAVVFAEDIPNI--PIANAISPAWDDLCPKYNANNP 516 Query: 599 TNPYPKIDSGLK 610 DSGL Sbjct: 517 -------DSGLA 521 >4A2F-A nrPDB Length = 497 Score = 192 bits (487), Expect = 4e-49, Method: Compositional matrix adjust. Identities = 163/517 (31%), Positives = 234/517 (45%), Gaps = 79/517 (15%) Query: 87 VFNLTEVDNWMGPDGVVKEKVMLINGNIMGPNIVANWGDTVEVTVINNL----VTNGTSI 142 V +LT + + PDG ++ + L+N P I N GD ++ VI+N+ + TSI Sbjct: 5 VADLTISNGAVSPDGFSRQAI-LVNDVFPSPLITGNKGDRFQLNVIDNMTNHTMLKSTSI 63 Query: 143 HWHGIHQKDTNLHDGANGVTECPIPPKGGQRTYRWRA-RQYGTSWYHSHFSAQYGNGVVG 201 HWHG Q TN DG V +CPI G Y ++ Q GT WYHSH S QY +G+ G Sbjct: 64 HWHGFFQHGTNWADGPAFVNQCPIS-TGHAFLYDFQVPDQAGTFWYHSHLSTQYCDGLRG 122 Query: 202 TIQI---NGPASLPYDID--LGVFPITDYYYRAADDLVHFTQNNAP-PFSDNVLINGTAV 255 I + N P + YD+D V + D+Y+ AA + AP P +D LING Sbjct: 123 PIVVYDPNDPHASLYDVDDDSTVITLADWYHLAA-------KVGAPVPTADATLINGLGR 175 Query: 256 NPNTGEGQYANVTLTPGKRHRLRILNTSTENHFQVSLVNHTMTVIAADMVPVNAMTVDSL 315 + T A +T+T GKR+R R+++ S + ++ S+ H++TVI AD V + TVDSL Sbjct: 176 SAATLAADLAVITVTKGKRYRFRLVSLSCDPNYTFSIDGHSLTVIEADSVNLKPHTVDSL 235 Query: 316 FLAVGQRYDVVIDASRAPDNYWFNV--TFGGQAACGGSLNPHPAAIFHYAGAPGGLPTDE 373 + QRY V++A + DNYW G Q GG+ +AI Y GA PT Sbjct: 236 QIFAAQRYSFVLNADQDVDNYWIRALPNSGTQNFAGGT----NSAILRYDGAAPVEPTTS 291 Query: 374 GTPPVDHQCLDTLDVRPVVPRSVPVNSFVKRPDNTLPVALDLTGTPLFVWKVNGSDINVD 433 TP P+V ++ P + P +DL F + G + ++ Sbjct: 292 QTP----------STNPLVESALTTLKGTAAPGSPTPGGVDLALNMAFGFA--GGNFTIN 339 Query: 434 WGK------PIIDYILTGNTSYPVSDNIVQVDAVDQWTYWLIENDPEGPFSL-------- 479 P++ IL+G S D + + + + + + SL Sbjct: 340 GASFTPPTVPVLLQILSGAQS--------AADLLPAGSVYSLPANADIEISLPATAAAPG 391 Query: 480 -PHPMHLHGHDFLVLGRSPDVPAASQQRFVFDPAVDLARLNGDNPPRRDTTMLPA-GGWL 537 PHP HLHGH F V V +A + N NP RD A G + Sbjct: 392 FPHPFHLHGHVFAV------VRSAGSSTY-----------NYANPVYRDVVSTGAPGDNV 434 Query: 538 LLAFRTDNPGAWLFHCHIAWHVSGGLSVDFLERPADL 574 + FRTDNPG W HCHI +H+ G +V E D+ Sbjct: 435 TIRFRTDNPGPWFLHCHIDFHLEAGFAVVMAEDIPDV 471 >2H5U-A nrPDB Length = 499 Score = 189 bits (479), Expect = 4e-48, Method: Compositional matrix adjust. Identities = 160/501 (31%), Positives = 238/501 (47%), Gaps = 66/501 (13%) Query: 99 PDGVVKEKVMLINGNIMGPNIVANWGDTVEVTVINNLVTNG----TSIHWHGIHQKDTNL 154 PDG ++ V ++NG GP + N GD ++ VI+NL + TS+HWHG Q+ TN Sbjct: 17 PDGFSRQAV-VVNGVTPGPLVAGNIGDRFQLNVIDNLTNHTMLKTTSVHWHGFFQQGTNW 75 Query: 155 HDGANGVTECPIPPKGGQRTYRWRA-RQYGTSWYHSHFSAQYGNGVVGTIQI---NGPAS 210 DG + +CPI P G Y ++ Q GT WYHSH S QY +G+ G + N P + Sbjct: 76 ADGPAFINQCPISP-GHSFLYDFQVPNQAGTFWYHSHLSTQYCDGLRGPFVVYDPNDPHA 134 Query: 211 LPYDIDLGVFPIT--DYYYRAADDLVHFTQNNAPPFSDNVLINGTAVNPNTGEGQYANVT 268 YD+D IT D+Y+ AA F P +D+ LING P+ Q + V+ Sbjct: 135 SRYDVDNDDTTITLADWYHTAAKLGPAF-----PNGADSTLINGKGRAPSDSSAQLSVVS 189 Query: 269 LTPGKRHRLRILNTSTENHFQVSLVNHTMTVIAADMVPVNAMTVDSLFLAVGQRYDVVID 328 +T GKR+R R+++ S + +F S+ H T+I D V + DS+ + QRY ++ Sbjct: 190 VTKGKRYRFRLVSLSCDPNFTFSIDGHNNTIIETDSVNSQPLNTDSIQIFAAQRYSFTLN 249 Query: 329 ASRAPDNYWF--NVTFGGQAACGGSLNPHPAAIFHYAGAPGGLPTDEGTPPVDHQCLDTL 386 A++A DNYW N FG GG +N +AI Y GAP PT + Q L+ Sbjct: 250 ANQAVDNYWIRANPNFGNVGFNGG-IN---SAILRYDGAPAVEPTTNQS--TSTQPLNET 303 Query: 387 DVRPVVPRSVPVNSFVKRPDNTLPVALDLTGTPLFVWKVNGSDINVDWGKPIIDYILTGN 446 ++ P+V VP + D + +A + G+ F +NG+ P++ IL+G Sbjct: 304 NLHPLVSTPVPGSPAAGGVDKAINMAFNFNGSNFF---INGASFTPP-SVPVLLQILSGA 359 Query: 447 TSYPVSDNIVQVDAVDQWTYWLIENDPEGPFSL---------PHPMHLHGHDFLVLGRSP 497 + D + + + + ++ S PHP HLHGH F V Sbjct: 360 QT--------AQDLLPSGSVYTLPSNASIEISFPATAAAPGAPHPFHLHGHVFAV----- 406 Query: 498 DVPAASQQRFVFDPAVDLARLNGDNPPRRD--TTMLPAGG-WLLLAFRTDNPGAWLFHCH 554 V +A + N NP RD +T PA G + + F T+NPG W HCH Sbjct: 407 -VRSAGSTVY-----------NYSNPIFRDVVSTGTPAAGDNVTIRFLTNNPGPWFLHCH 454 Query: 555 IAWHVSGGLSVDFLERPADLR 575 I +H+ GG +V E D++ Sbjct: 455 IDFHLEGGFAVVQAEDVPDVK 475 >5MIA-A nrPDB Length = 546 Score = 187 bits (476), Expect = 9e-48, Method: Compositional matrix adjust. Identities = 156/488 (31%), Positives = 226/488 (46%), Gaps = 49/488 (10%) Query: 97 MGPDGVVKEKVMLINGNIMGPNIVANWGDTVEVTVINNL----VTNGTSIHWHGIHQKDT 152 + PDG + V L G GP I N GD ++TV N+L + TSIHWHG+ QK T Sbjct: 35 ISPDGFSRPAV-LAGGTFPGPTIAGNTGDNFQITVFNDLTDPSMLTDTSIHWHGLFQKGT 93 Query: 153 NLHDGANGVTECPIPPKGGQRTYRWRA-RQYGTSWYHSHFSAQYGNGVVGTIQI---NGP 208 N DG VT+CPI G Y + Q GT WYHSH S QY +G+ G + N P Sbjct: 94 NWADGPAFVTQCPII-TGQSFDYNFNVPGQAGTFWYHSHLSTQYCDGLRGPFVVYDPNDP 152 Query: 209 ASLPYDID--LGVFPITDYYYRAADDLVHFTQNNAPPFSDNVLINGTAVN-PNTGEGQYA 265 + YD+D + + D+Y+ A A +D LING + NT + Sbjct: 153 NASLYDVDDDTTIITLADWYHTLAQQ----EPIGAAITADATLINGLGRSFTNTTASPLS 208 Query: 266 NVTLTPGKRHRLRILNTSTENHFQVSLVNHTMTVIAADMVPVNAMTVDSLFLAVGQRYDV 325 +T+ GKR+R+R+++ S + ++ S+ H MT+I D V +TVD + + QRY Sbjct: 209 VITVQSGKRYRMRLVSISCDPNYLFSIDGHDMTIIEVDGVNSQQLTVDQIQIFAAQRYSF 268 Query: 326 VIDASRAPDNYWFNV--TFGGQAACGGSLNPHPAAIFHYAGAPGGLPTDEGTPPVDHQCL 383 V++A++ NYW GGQ GG +N +AI Y GA PT + + Sbjct: 269 VLNANQPVGNYWIRAQPNSGGQGFDGG-IN---SAILRYEGATVEDPTTTAPTTFSNPLV 324 Query: 384 DTLDVRPVVPRSVPVNSFVKRPDNTLPVALDLTGTPLFVWKVNGSDINVDWGKPIIDYIL 443 +T D+ P+ VP F D+ L + L + V+ V P++ IL Sbjct: 325 ET-DLHPLADLGVPGQPFRGGADDPLVLNLAFANGRFSIDGVSFVPPTV----PVLLQIL 379 Query: 444 TGNTSYPVSDNIVQVDAVDQWTYWLIEND-PEGPFSLPHPMHLHGHDFLVLGRSPDVPAA 502 +G + D + + + +IE P G PHP HLHGH+F V+ + + Sbjct: 380 SGAQN--AQDLLPAGSVISLPSNSVIEVALPAGAAGGPHPFHLHGHNFAVVQSANN---- 433 Query: 503 SQQRFVFDPAVDLARLNGDNPPRRDTTMLPA-GGWLLLAFRTDNPGAWLFHCHIAWHVSG 561 A N NP RDT + G + + F T+NPG W HCHI WH+ Sbjct: 434 -------------ATPNYVNPIWRDTVSIGGTGDNVTIRFTTNNPGPWFLHCHIDWHLEA 480 Query: 562 GLSVDFLE 569 G ++ F E Sbjct: 481 GFAIVFAE 488 >3KW7-A nrPDB Length = 502 Score = 187 bits (475), Expect = 1e-47, Method: Compositional matrix adjust. Identities = 162/514 (31%), Positives = 232/514 (45%), Gaps = 69/514 (13%) Query: 87 VFNLTEVDNWMGPDGVVKEKVMLINGNIMGPNIVANWGDTVEVTVINNL----VTNGTSI 142 V +LT + + PDG + V+ NG GP I N GD ++ VI+NL + T+I Sbjct: 5 VTDLTISNADVTPDGFTRAAVVA-NGVFPGPLITGNKGDNFQINVIDNLTNATMLKTTTI 63 Query: 143 HWHGIHQKDTNLHDGANGVTECPIPPKGGQRTYRWRA-RQYGTSWYHSHFSAQYGNGVVG 201 HWHG+ Q TN DG V +CPI G Y + Q GT WYHSH S QY +G+ G Sbjct: 64 HWHGLFQHGTNWADGPAFVNQCPIA-SGNSFLYDFTVPDQAGTFWYHSHLSTQYCDGLRG 122 Query: 202 TIQINGPASLPY------DIDLGVFPITDYYYRAADDLVHFTQNNAPPFSDNVLINGTAV 255 + + P+ PY D D V ++D+Y+ AA F PP +D+VLING Sbjct: 123 PLVVYDPSD-PYASMYDVDDDTTVITLSDWYHTAAKLGPAF-----PPNADSVLINGLGR 176 Query: 256 NPNTGEGQYANVTLTPGKRHRLRILNTSTENHFQVSLVNHTMTVIAADMVPVNAMTVDSL 315 A +T+ KR+R R+++ S + +F S+ H MT+I D V + VDS+ Sbjct: 177 FAGGNASDLAVITVEQNKRYRFRLVSLSCDPNFTFSIDGHNMTIIEVDGVNHEPLEVDSI 236 Query: 316 FLAVGQRYDVVIDASRAPDNYWFN-VTFGGQAACGGSLNPHPAAIFHYAGAPGGLPTDEG 374 + QRY V++A+++ DNYW + G G LN +AI Y+GA PT Sbjct: 237 QIFASQRYSFVLNATQSVDNYWIRAIPNTGTIDTTGGLN---SAILRYSGADIVDPTANA 293 Query: 375 TPPVDHQCLDTLDVRPVVPRSVPVNSFVKRPDNTLPVALDLTGT--------------PL 420 T V L D+ P+ + P + V D + + GT P+ Sbjct: 294 TTSV--IPLVETDLVPLDSPAAPGDPVVGGVDLAMNLDFSFNGTNFFINNETLIPPTVPV 351 Query: 421 FVWKVNGSDINVDWGKPIIDYILTGNTSYPVSDNIVQVDAVDQWTYWLIENDPEGPFSLP 480 + ++G+ D Y L N++ +S I V+ V N P P Sbjct: 352 LLQILSGAQSASDLLPTGSVYTLPLNSTIELSFPITTVNGV--------TNAPGA----P 399 Query: 481 HPMHLHGHDFLVLGRSPDVPAASQQRFVFDPAVDLARLNGDNPPRRDTTMLP-AGGWLLL 539 HP HLHGH F V+ + +S +V NP RRDT G + + Sbjct: 400 HPFHLHGHAFSVVRSA----GSSDYNYV-------------NPVRRDTVSTGNPGDNVTI 442 Query: 540 AFRTDNPGAWLFHCHIAWHVSGGLSVDFLERPAD 573 F TDN G W HCHI +H+ G ++ F E D Sbjct: 443 RFTTDNAGPWFLHCHIDFHLEAGFAIVFAEDTPD 476 >5EHF-A nrPDB Length = 497 Score = 186 bits (471), Expect = 4e-47, Method: Compositional matrix adjust. Identities = 161/503 (32%), Positives = 229/503 (45%), Gaps = 60/503 (11%) Query: 87 VFNLTEVDNWMGPDGVVKEKVMLINGNIMGPNIVANWGDTVEVTVINNL----VTNGTSI 142 V +L V+ + PDG + V L G GP I N GD ++ VI+ L + TSI Sbjct: 5 VADLKIVNANIQPDGFTRPAV-LAGGTFPGPLIKGNKGDNFQLNVIDELENEDMLKSTSI 63 Query: 143 HWHGIHQKDTNLHDGANGVTECPIPPKGGQRTYRWRA-RQYGTSWYHSHFSAQYGNGVVG 201 HWHG Q TN DG V +CPI G Y + Q GT WYHSH S QY +G+ G Sbjct: 64 HWHGFFQHGTNWADGPAFVNQCPIT-TGHSFLYNFHVPDQAGTFWYHSHLSTQYCDGLRG 122 Query: 202 TIQI---NGPASLPYDID--LGVFPITDYYYRAADDLVHFTQNNAPPFSDNVLINGTAVN 256 + + + P YD+D V + D+Y+ A + P D+ LING Sbjct: 123 PMVVYDPHDPLKQLYDVDDESTVMTLADWYHTLARQ-----EPPGPVTPDSTLINGLGRA 177 Query: 257 P-NTGEGQYANVTLTPGKRHRLRILNTSTENHFQVSLVNHTMTVIAADMVPVNAMTVDSL 315 P T + A +T+ G R+R+R++N S E ++ S+ NH +TVI AD V ++TV SL Sbjct: 178 PGQTTPSELAVLTVKRGTRYRIRLINISCEPNYHYSIDNHDLTVIEADGVSTQSLTVSSL 237 Query: 316 FLAVGQRYDVVIDASRAPDNYWFNVTFGGQA--ACGGSLNPHPAAIFHYAGAPGGLPTDE 373 + GQRY +++A++ NYW A G +N +AI Y GAP P Sbjct: 238 TIFAGQRYSFILNANQPVGNYWIRAQPNDAADVTFNGGIN---SAILRYEGAPVAEPNTT 294 Query: 374 GTPPVDHQCLDTLDVRPVVPRSVPVNSFVKRPDNTLPVALDLTGTPLFVWKVNGSDINVD 433 P D+ L +++RP V VP D + GT V V+ V Sbjct: 295 AGP--DNTPLLEVNIRPFVFTPVPGQPHAGGADFVKNLLFSFNGTNFQVDNVSFVPPTV- 351 Query: 434 WGKPIIDYILTGNTSYPVSDNIVQVDAVDQWTYWLIENDPEGPFSLP-------HPMHLH 486 PI+ IL+G ++ D + + +IE FS+P HP+HLH Sbjct: 352 ---PILLQILSG--AHTAQDLMPAGSIIPLPKNAVIE------FSMPGGVVGGGHPIHLH 400 Query: 487 GHDFLVLGRSPDVPAASQQRFVFDPAVDLARLNGDNPPRRDTTMLPAGGWLLLAFRTDNP 546 GH+F V+ RS + + V V++ GDN + + F T+NP Sbjct: 401 GHNFWVI-RSANSSVYNYNDPVIRDVVNIGT-TGDN--------------VTIRFETNNP 444 Query: 547 GAWLFHCHIAWHVSGGLSVDFLE 569 G W HCHI WH+ G +V E Sbjct: 445 GPWFLHCHIDWHLDLGFAVVMAE 467 >2QT6-A nrPDB Length = 498 Score = 185 bits (470), Expect = 4e-47, Method: Compositional matrix adjust. Identities = 159/506 (31%), Positives = 237/506 (46%), Gaps = 65/506 (12%) Query: 87 VFNLTEVDNWMGPDGVVKEKVMLINGNIMGPNIVANWGDTVEVTVINNL----VTNGTSI 142 V +LT + + PDG + +++N P I N GD ++ ++N + + TSI Sbjct: 5 VADLTVTNANIVPDGF-ERAAIVVNNVFPAPLITGNMGDNFQLNLVNQMTNHTMLKTTSI 63 Query: 143 HWHGIHQKDTNLHDGANGVTECPIPPKGGQRTYRWRA-RQYGTSWYHSHFSAQYGNGVVG 201 HWHG QK TN DG + +CPI G Y ++ Q GT WYHSH S QY +G+ G Sbjct: 64 HWHGFFQKGTNWADGPAFINQCPIA-SGNSFLYDFQVPGQAGTFWYHSHLSTQYCDGLRG 122 Query: 202 TIQI---NGPASLPYDID--LGVFPITDYYYRAADDLVHFTQNNAPPFSDNVLINGTAVN 256 + N P + YD+D V + D+Y+ AA F P +D+ LING + Sbjct: 123 PFVVYDPNDPHANLYDVDDESTVITLADWYHVAAKLGPRF-----PKGADSTLINGLGRS 177 Query: 257 PNTGEGQYANVTLTPGKRHRLRILNTSTENHFQVSLVNHTMTVIAADMVPVNAMTVDSLF 316 +T A +++T GKR+R R+++ S + ++ S+ +H +TVI AD V +TVDS+ Sbjct: 178 TSTPTADLAVISVTKGKRYRFRLVSLSCDPNYTFSIDSHQLTVIEADGVSTQPVTVDSIQ 237 Query: 317 LAVGQRYDVVIDASRAPDNYWF--NVTFGGQAACGGSLNPHPAAIFHYAGAPGGLPTDEG 374 + QRY V++A++ DNYW N FG G +AI Y A + Sbjct: 238 IFAAQRYSFVLNANQDVDNYWIRANPNFGTTGFADGV----NSAILRYDDA-------DP 286 Query: 375 TPPVDHQCLDTL----DVRPVVPRSVPVNSFVKRPDNTLPVALDLTGTPLFVWKVNGSDI 430 PV +Q TL D+ P+ VP N D L +A + GT F +NG Sbjct: 287 VEPVTNQTGTTLLLETDLHPLTSMPVPGNPTQGGADLNLNMAFNFDGTNFF---INGESF 343 Query: 431 NVDWGKPIIDYILTGNTSYPV--SDNIVQV--DAVDQWTYWLIENDPEGPFSLPHPMHLH 486 ++ I NT+ + S ++ + ++ + T+ P PHP HLH Sbjct: 344 TPPTVPVLLQIISGANTAQDLLPSGSVYSLPSNSSIEITFPATTAAPGA----PHPFHLH 399 Query: 487 GHDFLVLGRSPDVPAASQQRFVFDPAVDLARLNGDNPPRRD--TTMLP-AGGWLLLAFRT 543 GH F V V +A + N D+P RD +T P AG + + F+T Sbjct: 400 GHVFAV------VRSAGSTSY-----------NYDDPVWRDVVSTGTPQAGDNVTIRFQT 442 Query: 544 DNPGAWLFHCHIAWHVSGGLSVDFLE 569 DNPG W HCHI +H+ G +V E Sbjct: 443 DNPGPWFLHCHIDFHLDAGFAVVMAE 468 >1GYC-A nrPDB Length = 499 Score = 185 bits (469), Expect = 6e-47, Method: Compositional matrix adjust. Identities = 156/497 (31%), Positives = 232/497 (46%), Gaps = 54/497 (10%) Query: 97 MGPDGVVKEKVMLINGNIMGPNIVANWGDTVEVTVINNL----VTNGTSIHWHGIHQKDT 152 + PDG +++ ++ +NG P I GD ++ V++ L + TSIHWHG Q T Sbjct: 15 VSPDGFLRDAIV-VNGVFPSPLITGKKGDRFQLNVVDTLTNHTMLKSTSIHWHGFFQAGT 73 Query: 153 NLHDGANGVTECPIPPKGGQRTYRWRA-RQYGTSWYHSHFSAQYGNGVVGTIQI---NGP 208 N DG V +CPI G Y + Q GT WYHSH S QY +G+ G + P Sbjct: 74 NWADGPAFVNQCPIA-SGHSFLYDFHVPDQAGTFWYHSHLSTQYCDGLRGPFVVYDPKDP 132 Query: 209 ASLPYDID--LGVFPITDYYYRAADDLVHFTQNNAPPFSDNVLINGTAVNPNTGEGQYAN 266 + YD+D V +TD+Y+ AA F P +D LING + +T A Sbjct: 133 HASRYDVDNESTVITLTDWYHTAARLGPRF-----PLGADATLINGLGRSASTPTAALAV 187 Query: 267 VTLTPGKRHRLRILNTSTENHFQVSLVNHTMTVIAADMVPVNAMTVDSLFLAVGQRYDVV 326 + + GKR+R R+++ S + ++ S+ H +TVI D + + VDS+ + QRY V Sbjct: 188 INVQHGKRYRFRLVSISCDPNYTFSIDGHNLTVIEVDGINSQPLLVDSIQIFAAQRYSFV 247 Query: 327 IDASRAPDNYWF--NVTFGGQAACGGSLNPHPAAIFHYAGAPGGLPTDEGTPPVDHQCLD 384 ++A++ NYW N FG GG +N +AI Y GAP PT T V L Sbjct: 248 LNANQTVGNYWIRANPNFGTVGFAGG-IN---SAILRYQGAPVAEPTTTQTTSV--IPLI 301 Query: 385 TLDVRPVVPRSVPVNSFVKRPDNTLPVALDLTGTPLFVWKVNGSDINVDWGKPIIDYILT 444 ++ P+ VP + D L +A + GT F+ + + V P++ IL+ Sbjct: 302 ETNLHPLARMPVPGSPTPGGVDKALNLAFNFNGTNFFINNASFTPPTV----PVLLQILS 357 Query: 445 GNTSYPVSDNIVQVDAVDQWTYWLIE-NDPEGPFS--LPHPMHLHGHDFLVLGRSPDVPA 501 G + D + + IE P + PHP HLHGH F V V + Sbjct: 358 GAQT--AQDLLPAGSVYPLPAHSTIEITLPATALAPGAPHPFHLHGHAFAV------VRS 409 Query: 502 ASQQRFVFDPAVDLARLNGDNPPRRD--TTMLPAGG-WLLLAFRTDNPGAWLFHCHIAWH 558 A + N ++P RD +T PA G + + F+TDNPG W HCHI +H Sbjct: 410 AGSTTY-----------NYNDPIFRDVVSTGTPAAGDNVTIRFQTDNPGPWFLHCHIDFH 458 Query: 559 VSGGLSVDFLERPADLR 575 + G ++ F E AD++ Sbjct: 459 LEAGFAIVFAEDVADVK 475 >4JHU-A nrPDB Length = 496 Score = 182 bits (463), Expect = 3e-46, Method: Compositional matrix adjust. Identities = 159/512 (31%), Positives = 229/512 (44%), Gaps = 69/512 (13%) Query: 87 VFNLTEVDNWMGPDGVVKEKVMLINGNIMGPNIVANWGDTVEVTVINNL----VTNGTSI 142 V +LT D + PDG ++ + L+N P I N GD ++ VI+N+ + TSI Sbjct: 5 VTDLTISDGPVSPDGFTRQAI-LVNNQFPSPLITGNKGDRFQLNVIDNMNNHTMLKSTSI 63 Query: 143 HWHGIHQKDTNLHDGANGVTECPIPPKGGQRTYRWRA-RQYGTSWYHSHFSAQYGNGVVG 201 HWHG Q TN DG V +CPI P G Y ++ Q GT WYHSH S QY +G+ G Sbjct: 64 HWHGFFQHGTNWADGPAFVNQCPISP-GHSFLYDFQVPDQAGTFWYHSHLSTQYCDGLRG 122 Query: 202 TIQINGPASLPYDI-----DLGVFPITDYYYRAADDLVHFTQNNAPPFSDNVLINGTAVN 256 I + P D+ D V + D+Y+ AA A P +D LING + Sbjct: 123 PIVVYDPQDPHKDLYDVDDDSTVITLADWYHLAAK------VGPAVPTADATLINGLGRS 176 Query: 257 PNTGEGQYANVTLTPGKRHRLRILNTSTENHFQVSLVNHTMTVIAADMVPVNAMTVDSLF 316 +T A +++T GKR+R R+++ S + + S+ HTMTVI AD V + VDS+ Sbjct: 177 ISTLNADLAVISVTKGKRYRFRLVSLSCDPNHTFSIDGHTMTVIEADSVNLKPQVVDSIQ 236 Query: 317 LAVGQRYDVVIDASRAPDNYWFNVT-FGGQAACGGSLNPHPAAIFHYAGAPGGLPTDEGT 375 + QRY V++A + NYW G G +N +AI Y GA PT T Sbjct: 237 IFAAQRYSFVLNADQDIGNYWIRAMPNSGTRNFDGGVN---SAILRYDGADPVEPTTTQT 293 Query: 376 P---PVDHQCLDTLDVRPVVPRSVPVNSFVKRPDNTLPVALDLTGTPLFVWKVNGSDINV 432 P P+ L TL+ + P + D + +A G + +NG+ Sbjct: 294 PSSQPLVESALTTLE-----GTAAPGSPTAGGVDLAINMAFGFAGG---RFTINGASFTP 345 Query: 433 DWGKPIIDYILTGNTSYPVSDNIVQVDAVDQWTYWLIENDPEGPFSL---------PHPM 483 P++ IL+G + D + + + + + + SL PHP Sbjct: 346 P-TVPVLLQILSGAQN--------AQDLLPTGSVYSLPANADIEISLPATAAAPGFPHPF 396 Query: 484 HLHGHDFLVLGRSPDVPAASQQRFVFDPAVDLARLNGDNPPRRDTTMLPA-GGWLLLAFR 542 HLHGH F V V +A + N NP RD + G + + FR Sbjct: 397 HLHGHTFAV------VRSAGSSTY-----------NYANPVYRDVVSTGSPGDNVTIRFR 439 Query: 543 TDNPGAWLFHCHIAWHVSGGLSVDFLERPADL 574 TDNPG W HCHI +H+ G +V E D+ Sbjct: 440 TDNPGPWFLHCHIDFHLEAGFAVVMAEDIPDV 471 >3T6Z-A nrPDB Length = 495 Score = 180 bits (456), Expect = 2e-45, Method: Compositional matrix adjust. Identities = 152/500 (30%), Positives = 231/500 (46%), Gaps = 53/500 (10%) Query: 87 VFNLTEVDNWMGPDGVVKEKVMLINGNIMGPNIVANWGDTVEVTVINNLVTNG----TSI 142 V +L V+ + PDG V+ V G GP I N GD ++ N L+ TSI Sbjct: 6 VTDLHIVNADIVPDGFVRPAVNA-GGTFPGPVIAGNVGDNFQIVTFNQLIECSMLVDTSI 64 Query: 143 HWHGIHQKDTNLHDGANGVTECPIPPKGGQRTYRWRA-RQYGTSWYHSHFSAQYGNGVVG 201 HWHG QK TN DG +T+CPI G +Y + GT WYHSH + QY +G+ G Sbjct: 65 HWHGEFQKGTNWADGPAFITQCPII-VGNSFSYNFNVPGMAGTYWYHSHLTTQYCDGLRG 123 Query: 202 TIQI---NGPASLPYDID--LGVFPITDYYYRAADDLVHFTQNNAPPFSDNVLINGTA-V 255 + N P + YD+D + + D+Y+ A ++ +D+ LI+G Sbjct: 124 PFVVYDPNDPDANLYDVDDDTTIITLADWYHVLAKEM----GAGGAITADSTLIDGLGRT 179 Query: 256 NPNTGEGQYANVTLTPGKRHRLRILNTSTENHFQVSLVNHTMTVIAADMVPVNAMTVDSL 315 + N + +T+ GKR+R+R+++ S + ++ S+ H MT+I D V +TVD + Sbjct: 180 HVNVAAVPLSVITVEVGKRYRMRLVSISCDPNYDFSIDGHDMTIIETDGVDSQELTVDEI 239 Query: 316 FLAVGQRYDVVIDASRAPDNYWF--NVTFGGQAACGGSLNPHPAAIFHYAGAPGGLPTDE 373 + QRY V++A++ NYW N GG+ GG +N +AI Y GA P Sbjct: 240 QIFAAQRYSFVLNANQPVGNYWIRANPNSGGEGFDGG-IN---SAILRYDGATTADPVTV 295 Query: 374 GTPPVDHQCLDTLDVRPVVPRSVPVNSFVKRPDNTLPVALDLTGTPLFVWKVNGSDINVD 433 + V +CL D+ P+ VP N D L ++L + V+ + V Sbjct: 296 AS-TVHTKCLIETDLHPLSRNGVPGNPHQGGADCNLNLSLGFACGNFVINGVSFTPPTV- 353 Query: 434 WGKPIIDYILTG-NTSYPV--SDNIVQVDAVDQWTYWLIENDPEGPFSLPHPMHLHGHDF 490 P++ I +G NT+ + S +++ + + L P G PHP HLHGHDF Sbjct: 354 ---PVLLQICSGANTAADLLPSGSVISLPSNSTIEIAL----PAGAAGGPHPFHLHGHDF 406 Query: 491 LVLGRSPDVPAASQQRFVFDPAVDLARLNGDNPPRRDTTMLPA-GGWLLLAFRTDNPGAW 549 V + + + N D+P RD + G + + F TDNPG W Sbjct: 407 AVSESASN-----------------STSNYDDPIWRDVVSIGGVGDNVTIRFCTDNPGPW 449 Query: 550 LFHCHIAWHVSGGLSVDFLE 569 HCHI WH+ G ++ F E Sbjct: 450 FLHCHIDWHLDAGFAIVFAE 469 >5Z1X-A nrPDB Length = 495 Score = 180 bits (456), Expect = 2e-45, Method: Compositional matrix adjust. Identities = 164/528 (31%), Positives = 237/528 (44%), Gaps = 62/528 (11%) Query: 87 VFNLTEVDNWMGPDGVVKEKVMLINGNIMGPNIVANWGDTVEVTVINNL----VTNGTSI 142 V ++ V+ + PDG + V L G GP I GD ++ V+++L + TSI Sbjct: 5 VTDIHIVNKDIAPDGFSRPSV-LAGGTFPGPLITGQKGDNFKLNVVDDLTDASMLKSTSI 63 Query: 143 HWHGIHQKDTNLHDGANGVTECPIPPKGGQRTYRWRA-RQYGTSWYHSHFSAQYGNGVVG 201 HWHG QK TN DG V +CPI G Y ++ Q GT WYHSH S QY +G+ G Sbjct: 64 HWHGFFQKGTNWADGPAFVNQCPIS-TGNSFLYNFQVPDQAGTYWYHSHLSTQYCDGLRG 122 Query: 202 TIQI---NGPASLPYDID--LGVFPITDYYYRAADDLVHFTQNNAPPFSDNVLINGTAVN 256 + P YD+D V + D+Y+ A +V +D LING N Sbjct: 123 AFVVYDPTDPHKALYDVDDESTVITLADWYHTLARQIVGVA------IADTTLINGLGRN 176 Query: 257 PNT-GEGQYANVTLTPGKRHRLRILNTSTENHFQVSLVNHTMTVIAADMVPVNAMTVDSL 315 N + A + + GKR+RLR+++ S + ++ S+ NH +I D V + VDS+ Sbjct: 177 TNGPADAALAVINVEAGKRYRLRLVSISCDPNYVFSIDNHDFNIIEVDGVNSKPLNVDSI 236 Query: 316 FLAVGQRYDVVIDASRAPDNYWF--NVTFGGQAACGGSLNPHPAAIFHYAGAPGGLPTDE 373 + GQRY V++A++ NYW N G GG +N +AI Y GAP PT Sbjct: 237 QIFAGQRYSAVLNANQPVGNYWVRANPNLGTTGFTGG-IN---SAILRYKGAPVAEPTTT 292 Query: 374 GTPPVDHQCLDTLDVRPVVPRSVPVNSFVKRPDNTLPVALDLTGTPLFVWKVNGSDIN-- 431 T + L ++RP+V S+PV P + P +D+ + + IN Sbjct: 293 QT--TSTKPLQEPNLRPLV--SMPV------PGSATPGGVDVVHNLILGFSAGKFTINGA 342 Query: 432 --VDWGKPIIDYILTGNTSYPVSDNIVQVDAVDQWTYWLIE-NDPEGPFSLPHPMHLHGH 488 P++ IL+G T+ D + + IE G PHP HLHGH Sbjct: 343 AFTPPSVPVLLQILSGTTN--AQDLLPSGSVITLPIGKTIELTLAAGVLGGPHPFHLHGH 400 Query: 489 DFLVLGRSPDVPAASQQRFVFDPAV-DLARLNGDNPPRRDTTMLPAGGWLLLAFRTDNPG 547 +F V+ RS A DP V D+ G G + + F TDNPG Sbjct: 401 NFHVV-RS----AGQTTPNYVDPIVRDVVNTGG------------TGDNVTIRFTTDNPG 443 Query: 548 AWLFHCHIAWHVSGGLSVDFLERPADLRQRISQEDEDDFNRVCDEWRA 595 W HCHI WH+ G +V F E + + D+N +C+ + A Sbjct: 444 PWFLHCHIDWHLEAGFAVVFAEGVN--QTNAANPTPADWNNLCNIYNA 489 >1ZPU-A nrPDB Length = 534 Score = 152 bits (384), Expect = 4e-37, Method: Compositional matrix adjust. Identities = 142/532 (26%), Positives = 229/532 (43%), Gaps = 57/532 (10%) Query: 84 QSYVFNLTEVDNWMGPDGVVKEKVMLINGNIMGPNIVANWGDTVEVTVINNLVTNGTSIH 143 +++ FN T ++ DG+ V+ NG P+I N GD V++ + N + TS+H Sbjct: 1 ETHTFNWTTGWDYRNVDGLKSRPVITCNGQFPWPDITVNKGDRVQIYLTNGMNNTNTSMH 60 Query: 144 WHGIHQKDTNLHDGANGVTECPIPPKGGQRTYRWRA-RQYGTSWYHSHFSAQYGNGVVGT 202 +HG+ Q T DG +T+CPI P G Y + GT WYHSH QY +G+ G Sbjct: 61 FHGLFQNGTASMDGVPFLTQCPIAP-GSTMLYNFTVDYNVGTYWYHSHTDGQYEDGMKGL 119 Query: 203 IQINGPASLPYDIDLGV-FPITDYYYRAADDLVH-----FTQNNAPPFSDNVLINGTAVN 256 I S PYD D + ++++Y+ DL + A P N+++N T Sbjct: 120 FIIKDD-SFPYDYDEELSLSLSEWYHDLVTDLTKSFMSVYNPTGAEPIPQNLIVNNT--- 175 Query: 257 PNTGEGQYANVT--LTPGKRHRLRILNTSTENHFQVSLVNHTMTVIAADMVPVNAMTVDS 314 N+T + P + LRI+N + +H MTV+ D + D Sbjct: 176 --------MNLTWEVQPDTTYLLRIVNVGGFVSQYFWIEDHEMTVVEIDGITTEKNVTDM 227 Query: 315 LFLAVGQRYDVVIDASRAPDNYW-----FNVTFGGQAACGGSLNPHPAAIFHYAGAPGGL 369 L++ V QRY V++ D + F+ T LN +++ A L Sbjct: 228 LYITVAQRYTVLVHTKNDTDKNFAIMQKFDDTMLDVIPSDLQLNATSYMVYNKTAA---L 284 Query: 370 PTDEGTPPVDHQCLDTLDVRPVVPRSVPVNSFVKRPDNTLPVALDLTGTPLFVWKVNGSD 429 PT +D+ LD ++P ++ PD+ + V + + NG + Sbjct: 285 PTQNYVDSIDN-FLDDFYLQPYEKEAI-----YGEPDHVITVDVVMDNLK------NGVN 332 Query: 430 I----NVDWGKPIIDYILTGNTSYPVSDNIVQVDAVDQWTYWLIENDPEGPFSL------ 479 N+ + P + ++T +S ++N ++ + T+ ++E D L Sbjct: 333 YAFFNNITYTAPKVPTLMTVLSSGDQANN-SEIYGSNTHTF-ILEKDEIVEIVLNNQDTG 390 Query: 480 PHPMHLHGHDFLVLGRSPDV-PAASQQRFVFDPAVDLARLNGDNPPRRDTTMLPAGGWLL 538 HP HLHGH F + R A + FDP D + P RRDT + + Sbjct: 391 THPFHLHGHAFQTIQRDRTYDDALGEVPHSFDP--DNHPAFPEYPMRRDTLYVRPQSNFV 448 Query: 539 LAFRTDNPGAWLFHCHIAWHVSGGLSVDFLERPADLRQRISQEDEDDFNRVC 590 + F+ DNPG W FHCHI WH+ GL + +E P ++ SQ+ ++ VC Sbjct: 449 IRFKADNPGVWFFHCHIEWHLLQGLGLVLVEDPFGIQDAHSQQLSENHLEVC 500 >1ASO-A nrPDB Length = 552 Score = 142 bits (358), Expect = 4e-34, Method: Compositional matrix adjust. Identities = 148/531 (27%), Positives = 221/531 (41%), Gaps = 99/531 (18%) Query: 107 VMLINGNIMGPNIVANWGDTVEVTVINNLVTNGTSIHWHGIHQKDTNLHDGANGVTECPI 166 VM ING GP I AN GD+V V + N L T G IHWHGI Q+ T DG +++C I Sbjct: 24 VMGINGQFPGPTIRANAGDSVVVELTNKLHTEGVVIHWHGILQRGTPWADGTASISQCAI 83 Query: 167 PPKGGQRTYRWRARQYGTSWYHSHFSAQYGNGVVGTIQINGPAS----LPYDIDLGVFPI 222 P G Y + GT +YH H Q G+ G++ ++ P YD ++ + + Sbjct: 84 NP-GETFFYNFTVDNPGTFFYHGHLGMQRSAGLYGSLIVDPPQGKKEPFHYDGEINLL-L 141 Query: 223 TDYYYRAADDLVHFTQN--NAPPFS-----DNVLING-------------TAVNPNTGEG 262 +D+++++ +H + ++ P +L+NG + + P +G Sbjct: 142 SDWWHQS----IHKQEVGLSSKPIRWIGEPQTILLNGRGQFDCSIAAKYDSNLEPCKLKG 197 Query: 263 QYANV----TLTPGKRHRLRILNTSTENHFQVSLVNHTMTVIAADMVPVNAMTVDSLFLA 318 + ++P K +R+RI +T+ ++ NH + V+ AD V + + Sbjct: 198 SESCAPYIFHVSPKKTYRIRIASTTALAALNFAIGNHQLLVVEADGNYVQPFYTSDIDIY 257 Query: 319 VGQRYDVVIDASRAP-DNYWFNVTFGGQAACGGSLNPHPAAIFHYAGAPGGLPTDEGTPP 377 G+ Y V+I + P +NYW +V G A + P + + + LPT +PP Sbjct: 258 SGESYSVLITTDQNPSENYWVSV---GTRARHPNTPPGLTLLNYLPNSVSKLPT---SPP 311 Query: 378 VDHQCLDTLD------VRPVVPRSVP------------------VNSFVKRPDNTLPVAL 413 D D R P +N +VK N V+L Sbjct: 312 PQTPAWDDFDRSKNFTYRITAAMGSPKPPVKFNRRIFLLNTQNVINGYVKWAIND--VSL 369 Query: 414 DLTGTP-LFVWKVN--------------GSDINVDWGKPIIDYILTGNTSYPVSDNIVQV 458 L TP L K N D ++D P + GN Y V V Sbjct: 370 ALPPTPYLGAMKYNLLHAFDQNPPPEVFPEDYDID-TPPTNEKTRIGNGVYQFKIGEV-V 427 Query: 459 DAVDQWTYWLIENDPEGPFSLPHPMHLHGHDFLVLGRSPDVPAASQQRFVFDPAVDLARL 518 D + Q + EN S HP HLHGHDF VLG +A ++ + L Sbjct: 428 DVILQNANMMKEN-----LSETHPWHLHGHDFWVLGYGDGKFSAEEE----------SSL 472 Query: 519 NGDNPPRRDTTMLPAGGWLLLAFRTDNPGAWLFHCHIAWHVSGGLSVDFLE 569 N NPP R+T ++ GW + F DNPG W FHCHI H+ G+ V F E Sbjct: 473 NLKNPPLRNTVVIFPYGWTAIRFVADNPGVWAFHCHIEPHLHMGMGVVFAE 523 Score = 31.6 bits (70), Expect = 0.95, Method: Compositional matrix adjust. Identities = 22/91 (24%), Positives = 39/91 (42%), Gaps = 7/91 (7%) Query: 534 GGWLLLAFRTDNPGAWLFHCHIAWHVSGGLSVDFLERPADLRQRISQEDEDDFNRVCDEW 593 G F DNPG + +H H+ S GL + P ++ D + N + +W Sbjct: 86 GETFFYNFTVDNPGTFFYHGHLGMQRSAGLYGSLIVDPPQGKKEPFHYD-GEINLLLSDW 144 Query: 594 RAYWPTNPYPKIDSGLKRR--RWVEESEWLV 622 W + + K + GL + RW+ E + ++ Sbjct: 145 ---WHQSIH-KQEVGLSSKPIRWIGEPQTIL 171 >4F7K-A nrPDB Length = 425 Score = 96.7 bits (239), Expect = 3e-20, Method: Compositional matrix adjust. Identities = 121/477 (25%), Positives = 185/477 (38%), Gaps = 93/477 (19%) Query: 99 PDGVVKEKVMLINGNIMGPNIVANWGDTVEVTVINNLVTNGTSIHWHGIHQKDTNLHDGA 158 P+G ++ NG GP + A G+ ++ N + G+++HWHG+ + N DG Sbjct: 17 PEGEPATPMLGFNGGTPGPVLRARQGEVFDIR-FQNQIGEGSAVHWHGL--RIDNAMDGV 73 Query: 159 NGVTECPIPPKGGQRTYRWRARQYGTSWYHSHFSA--QYGNGVVGTIQINGPASLPYDID 216 G+T+ + GG+ Y +RA GT WYHSH + Q G+ G + + P D D Sbjct: 74 PGMTQ-DVVEAGGEFEYSFRAPDAGTFWYHSHNRSWEQVAKGLYGPLIVEEPTPPDVDHD 132 Query: 217 LGVFPITDYYYRAADDLVHFTQNNAPPFSDNVLINGTAVNPNTGEGQYANVTLTP----- 271 L + I D+ L +N L G +A + P Sbjct: 133 L-IIMIDDWRITENGVLADGFENMRDQAHQGRL------------GNFARALVEPVTPVR 179 Query: 272 -GKRHRLRILNTSTENHFQVSLVNHTMTVIAADMVP-VNAMTVDSLFLAVGQRYDVVIDA 329 G R RLR++N +T+ F V L V+A D +P V+ L LA QR D++ D Sbjct: 180 RGDRVRLRLINVATDRIFPVELEGVEGKVVALDGMPIVDPQEFSGLILAPAQRADIIADV 239 Query: 330 -SRAPDNYWFNVTFGGQAACGGSLNPHPAAIFHYAGAPGGLPTDEGTPPVDHQCLDTLDV 388 + AP + F G P G PV + +T Sbjct: 240 ITDAPIGFVFPTRDG--------------------------PYLLGEIPV--KGANTTRQ 271 Query: 389 RPVVPRSVPVNSFVKRPDNTLPVALDLTGTPLFVWKVNGSDINVDWGKPIIDY-ILTGNT 447 +P ++P N V PD V+L LT + G ++ + ++ I N Sbjct: 272 PSEIP-ALPPNE-VTSPDMGSAVSLTLT--------MEGGAMSRRMMQGMMGGDIWAFNG 321 Query: 448 SYPVSDNIVQVDAVDQWTYWLIENDPEGPFSLPHPMHLHGHDFLVLGRSPDVPAASQQRF 507 ++D + Q + ND P H +HLHGH F +G ++ A Sbjct: 322 QSGLTDTPLHSFERGQTARIRLVNDTRFP----HGIHLHGHHFFEVGADGNLGAL----- 372 Query: 508 VFDPAVDLARLNGDNPPRRDTTMLPAGGWLLLAFRTDNPGAWLFHCHIAWHVSGGLS 564 RDTT++ AG + DNPG WL HCH+ H + G+ Sbjct: 373 ------------------RDTTLVDAGETRDIVCVFDNPGNWLLHCHMLGHQAAGMK 411 >4E9V-A nrPDB Length = 339 Score = 86.3 bits (212), Expect = 4e-17, Method: Compositional matrix adjust. Identities = 78/272 (28%), Positives = 112/272 (41%), Gaps = 27/272 (9%) Query: 106 KVMLINGNIMGPNIVANWGDTVEVTVINNLVTNGTSIHWHGIHQKDTNLHDGANGVTECP 165 KV NG + GP I GD V V V NN T IHWHG+HQK T DG GVT+ P Sbjct: 24 KVFGFNGQVPGPLIHVQEGDDVIVNVTNNTSLPHT-IHWHGVHQKGTWRSDGVPGVTQQP 82 Query: 166 IPPKGGQRTYRWRARQYGTSWYHSHFSAQYGNGVVGT---IQINGPASLPYDIDLGVFPI 222 I G TY+++A + GT WYH H + GV G + ++ LP + Sbjct: 83 I-EAGDSYTYKFKADRIGTLWYHCHVNVNEHVGVRGMWGPLIVDPKQPLPIE-------- 133 Query: 223 TDYYYRAADDLVHFTQNNAPPFSDNVLINGTAVNPNTGEGQYAN-------VTLTPGKRH 275 R D++ +D GT +N A + + G Sbjct: 134 ----KRVTKDVIMMMSTWESAVADKYGEGGTPMNVADYFSVNAKSFPLTQPLRVKKGDVV 189 Query: 276 RLRILNTSTENHFQVSLVNHTMTVIAADMVPVNA-MTVDSLFLAVGQRYDVVIDASRAPD 334 ++R H S H M V D +P+++ D++ ++ G+RYDV+I+A P Sbjct: 190 KIRFFGAGGGIHAMHSH-GHDMLVTHKDGLPLDSPYYADTVLVSPGERYDVIIEADN-PG 247 Query: 335 NYWFNVTFGGQAACGGSLNPHPAAIFHYAGAP 366 + F+ GG P + Y G P Sbjct: 248 RFIFHDHVDTHVTAGGKHPGGPITVIEYDGVP 279 Score = 39.7 bits (91), Expect = 0.004, Method: Compositional matrix adjust. Identities = 40/164 (24%), Positives = 65/164 (39%), Gaps = 33/164 (20%) Query: 405 PDNTLPVALDLTGTPLFV---WKVNGSDINVDWGKP--IIDYILTGNTSYPVSDNI-VQV 458 P LP+ +T + + W+ +D + G P + DY S+P++ + V+ Sbjct: 126 PKQPLPIEKRVTKDVIMMMSTWESAVADKYGEGGTPMNVADYFSVNAKSFPLTQPLRVKK 185 Query: 459 DAVDQWTYWLIENDPEGPFSLPHPMHLHGHDFLVLGRSPDVPAASQQRFVFDPAVDLARL 518 V + ++ G H MH HGHD LV + L Sbjct: 186 GDVVKIRFF-------GAGGGIHAMHSHGHDMLVTHKD--------------------GL 218 Query: 519 NGDNPPRRDTTMLPAGGWLLLAFRTDNPGAWLFHCHIAWHVSGG 562 D+P DT ++ G + DNPG ++FH H+ HV+ G Sbjct: 219 PLDSPYYADTVLVSPGERYDVIIEADNPGRFIFHDHVDTHVTAG 262 Score = 29.3 bits (64), Expect = 6.0, Method: Compositional matrix adjust. Identities = 21/78 (26%), Positives = 27/78 (34%), Gaps = 24/78 (30%) Query: 478 SLPHPMHLHGHDFLVLGRSPDVPAASQQRFVFDPAVDLARLNGDNPPRRDTTMLPAGGWL 537 SLPH +H HG RS VP +QQ + AG Sbjct: 54 SLPHTIHWHGVHQKGTWRSDGVPGVTQQP------------------------IEAGDSY 89 Query: 538 LLAFRTDNPGAWLFHCHI 555 F+ D G +HCH+ Sbjct: 90 TYKFKADRIGTLWYHCHV 107 >5B7E-A nrPDB Length = 526 Score = 71.2 bits (173), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 118/502 (23%), Positives = 201/502 (40%), Gaps = 102/502 (20%) Query: 111 NGNIMGPNIVANWGDTVEVTVINNLVTNGTSIHWHGIHQKDTNLHDGANGVTECPIPPKG 170 NGN++GP + G V V + N L T T++HWHG+ + + G G+ IPP G Sbjct: 70 NGNLLGPAVKLQRGKAVTVDIYNQL-TEETTLHWHGL-EVPGEVDGGPQGI----IPP-G 122 Query: 171 GQRTYRWRARQ-YGTSWYHSHFSAQYGN----GVVGTIQINGPASLP------YDIDLGV 219 G+R+ Q T W+H H + G G+ G + I L + ID Sbjct: 123 GKRSVTLNVDQPAATCWFHPHQHGKTGRQVAMGLAGLVVIEDDEILKLMLPKQWGIDDVP 182 Query: 220 FPITDYYYRAADDLVHFTQNNAPP----FSDNVLINGTAVNPNTGEGQYANVTLTPGKRH 275 + D + +AD + + + F D +L NG A+ P Q+A P Sbjct: 183 VIVQDKKF-SADGQIDYQLDVMTAAVGWFGDTLLTNG-AIYP-----QHA----APRGWL 231 Query: 276 RLRILNTSTENHFQVSLV-NHTMTVIAAD--MVPVNAMTVDSLFLAVGQRYDVVIDASRA 332 RLR+LN + N + VIA+D ++P + V L + +G+R++V+++ + Sbjct: 232 RLRLLNGCNARSLNFATSDNRPLYVIASDGGLLP-EPVKVSELPVLMGERFEVLVEVN-- 288 Query: 333 PDNYWFNVTFGGQAACGGSL----NPHPAAIFH--YAGAPGGLPTDEGTPPVDHQCLDTL 386 DN F++ + G ++ PHP A G LP DTL Sbjct: 289 -DNKPFDLVTLPVSQMGMAIAPFDKPHPVMRIQPIAISASGALP-------------DTL 334 Query: 387 DVRPVVPRSVPVNSFVKRPDNTLPVALDLTGTPLFVWK--------VNGSDINVDWGKPI 438 P +P + V++ ++ LD+ G + + K ++ S + G Sbjct: 335 SSLPALPSLEGLT--VRKLQLSMDPMLDMMGMQMLMEKYGDQAMAGMDHSQMMGHMGHGN 392 Query: 439 IDYILTGNTSYPVSDNIVQVDAVD-----------QWTYWLIENDPEGPFSLPHPMHLHG 487 ++++ G N + A D Q+ W+I + + HP H+HG Sbjct: 393 MNHMNHGGKFDFHHANKINGQAFDMNKPMFAAAKGQYERWVISGVGD---MMLHPFHIHG 449 Query: 488 HDFLVLGRSPDVPAASQQRFVFDPAVDLARLNGDNPPRRDTTMLPAGGWLLLAFRTDNPG 547 F +L + PAA + + D ++ G+ +L+ F D P Sbjct: 450 TQFRILSENGKPPAAHRAGW-----KDTVKVEGNVSE------------VLVKFNHDAPK 492 Query: 548 --AWLFHCHIAWHVSGGLSVDF 567 A++ HCH+ H G+ + F Sbjct: 493 EHAYMAHCHLLEHEDTGMMLGF 514 >2YXV-A nrPDB Length = 446 Score = 70.1 bits (170), Expect = 3e-12, Method: Compositional matrix adjust. Identities = 117/483 (24%), Positives = 189/483 (39%), Gaps = 112/483 (23%) Query: 111 NGNIMGPNIVANWGDTVEVTVINNLVTNGTSIHWHGIHQKDTNLHDGANGVTECPIPPKG 170 NGN++GP + G V V + N L T T++HWHG+ + + G G+ IPP G Sbjct: 42 NGNLLGPAVKLQRGKAVTVDIYNQL-TEETTLHWHGL-EVPGEVDGGPQGI----IPP-G 94 Query: 171 GQRTYRWRARQ-YGTSWYHSHFSAQYGN----GVVGTIQINGPASLP------YDIDLGV 219 G+R+ Q T W+H H + G G+ G + I L + ID Sbjct: 95 GKRSVTLNVDQPAATCWFHPHQHGKTGRQVAMGLAGLVVIEDDEILKLMLPKQWGIDDVP 154 Query: 220 FPITDYYYRAADDLVHFTQNNAPP----FSDNVLINGTAVNPNTGEGQYANVTLTPGKRH 275 + D + +AD + + + F D +L NG A+ P Q+A P Sbjct: 155 VIVQDKKF-SADGQIDYQLDVMTAAVGWFGDTLLTNG-AIYP-----QHA----APRGWL 203 Query: 276 RLRILNTSTENHFQVSLV-NHTMTVIAAD--MVPVNAMTVDSLFLAVGQRYDVVIDASRA 332 RLR+LN + N + VIA+D ++P + V L + +G+R++V+++ + Sbjct: 204 RLRLLNGCNARSLNFATSDNRPLYVIASDGGLLP-EPVKVSELPVLMGERFEVLVEVN-- 260 Query: 333 PDNYWFNVTFGGQAACGGSL----NPHPAAIFH--YAGAPGGLPTDEGTPPVDHQCLDTL 386 DN F++ + G ++ PHP A G LP DTL Sbjct: 261 -DNKPFDLVTLPVSQMGMAIAPFDKPHPVMRIQPIAISASGALP-------------DTL 306 Query: 387 DVRPVVPRSVPVNSFVKRPDNTLPVALDLTGTPLFVWKVNGSDINVDWGKPIIDYILTGN 446 P +P S L +++D K+NG D KP+ Sbjct: 307 SSLPALP------SLEGLTVRKLQLSMDGGAN-----KINGQAF--DMNKPMF------- 346 Query: 447 TSYPVSDNIVQVDAVDQWTYWLIENDPEGPFSLPHPMHLHGHDFLVLGRSPDVPAASQQR 506 A Q+ W+I + + HP H+HG F +L + PAA + Sbjct: 347 -----------AAAKGQYERWVISGVGD---MMLHPFHIHGTQFRILSENGKPPAAHRAG 392 Query: 507 FVFDPAVDLARLNGDNPPRRDTTMLPAGGWLLLAFRTDNPG--AWLFHCHIAWHVSGGLS 564 + D ++ G+ +L+ F D P A++ HCH+ H G+ Sbjct: 393 W-----KDTVKVEGNVSE------------VLVKFNHDAPKEHAYMAHCHLLEHEDTGMM 435 Query: 565 VDF 567 + F Sbjct: 436 LGF 438 >3AW5-A nrPDB Length = 448 Score = 65.1 bits (157), Expect = 8e-11, Method: Compositional matrix adjust. Identities = 122/480 (25%), Positives = 188/480 (39%), Gaps = 95/480 (19%) Query: 114 IMGPNIVANWGDTVEVTVINNLVTNGTSIHWHGIHQKDTNLHDGANGVTECPIPPKGGQR 173 ++ P I+ G V++T+ N L T T +HWHG D N H+ A+ I P G Sbjct: 35 VLNPTIILRRGQRVDMTLKNKL-TEPTIVHWHGF---DVNWHNDAH--PSFAITP-GESY 87 Query: 174 TYRWR-ARQYGTSWYHSH----FSAQYGNGVVGTIQINGPAS---LPYDIDLGVFPITDY 225 Y + + GT YH H + Q+ G +G + + S Y ++ I+D Sbjct: 88 NYSFDVVNRAGTYLYHPHPHGLTAKQFYMGQLGLVIVEDSGSDLGFKYGVNDLPLVISDR 147 Query: 226 YYRAADDLVHFT--QNNAPPFSDNVLINGTAVNPNTGEGQYANVTLTPGKRHRLRILNTS 283 + + + T + A + VL+NG V G +RLR++N S Sbjct: 148 RFIGGAPVYNPTPMEMIAGFLGNAVLVNGVK----------DAVFKLSGGSYRLRLVNGS 197 Query: 284 TENHFQVSLVNHTMTVIAADMVPVNA------MTVDSLFLAVGQRYDVVIDASRAPDNYW 337 + +S+V V+ ++ V+ + V +LFLA +R +VV++ Y Sbjct: 198 NARLYMLSIVKKNGDVVPMRLIAVDQGFLARPIEVRALFLAPAERAEVVVELGEGV--YL 255 Query: 338 FNVTFGGQAACGGSLNPHPAAIFHYAGAPGGLPTDEGTPPVDHQCLDTLDVRPVVPRSVP 397 T P H G E P + T V +VP Sbjct: 256 LKNT--------------PFDPMHLEMGHG---MQEALPEGSEYTIATFLVEG-KGEAVP 297 Query: 398 VNSF------VKRPDNTLPVALDLTGTPLFVWKVNGSDINVDWGKPIIDYILTGNTSYPV 451 V + +P T AL L+G W +NG + W N S P+ Sbjct: 298 VEALSDPPPEPPKPTRTRRFALSLSGMQ---WTING----MFW-----------NASNPL 339 Query: 452 SDNIVQVDAVDQWTYWLIENDPEGPFSLPHPMHLHGHDFLVLGRSPDVPAASQQRFVFDP 511 ++ V V+ V+ W I ND S+PHPMHLHG ++ R D P R V + Sbjct: 340 FEH-VSVEGVELWE---IVNDKA---SMPHPMHLHGFPMWIIERK-DSP-----RQVAEL 386 Query: 512 AVD-LARLNGDNPPRRDTTMLPAGG--WLLLAFRTDNPGAWL-FHCHIAWHVSGGLSVDF 567 AVD RL D +DT ++ G +++ F G FHCH H GG+ ++ Sbjct: 387 AVDNRGRLPTD-LGLKDTVLIWPGETVKIVVNFDAKKRGQLFPFHCHNLEHEDGGMMINI 445 >6EVG-A nrPDB Length = 507 Score = 63.9 bits (154), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 107/500 (21%), Positives = 190/500 (38%), Gaps = 94/500 (18%) Query: 110 INGNIMGPNIVANWGDTVEVTVINNLVTNGTSIHWHGIHQKDTNLHDGANGVTECPIPPK 169 ING +GP + G+TV ++V N + GT++HWHG+ L G + V Sbjct: 59 INGAYLGPLVRLKNGETVTLSVENGM-DEGTTLHWHGLFVPSI-LDGGPHNVIAA----- 111 Query: 170 GGQRTYRWRARQYGT-SWYHSHF----SAQYGNGVVGTIQI----NGPASLPYDIDLGVF 220 G + +Q + +W+H H + Q G+ G + + + LP D + Sbjct: 112 GEAWKPEVKIQQPASFNWFHPHLHGNTARQAHLGIAGLMVVTDGKDAERGLPEDYGVDDI 171 Query: 221 PITDYYYRAAD----------DLVHFTQNNAPPFSDNVLINGTAVNPNTGEGQYANVTLT 270 P+ R + DL+H + N+++NG V+P Sbjct: 172 PLVLQDRRVIEGDKVYEPDIMDLMHGFRGG------NLIVNGI-VSPE---------ARV 215 Query: 271 PGKRHRLRILNTSTENHFQVSLV-NHTMTVIAADMVPV-NAMTVDSLFLAVGQRYDVVID 328 P RLRILN + +F V L N + V+A+D + N V+ L ++ G+RY+V++D Sbjct: 216 PASIVRLRILNGANARNFHVRLSDNRPLLVVASDGGFIGNPEPVERLTISPGERYEVLVD 275 Query: 329 ASR--APDNYWFNVTFGG----------QAACGGSLNPHPAAIFHYAGAPGGLPTDEGTP 376 S+ A D + GG AA G + P + L + Sbjct: 276 FSKGEATDLLTYGDDSGGDDLHLMRFVVDAALQGKVTKRPDRLDGPDAPDEKLSVKRRSF 335 Query: 377 PVDHQCLDTLDVRPVVPRSVPVNSFVKRPDNTLPVALDLTGTPLFVWKVNGSDINVDWGK 436 D + + + + + P N + + + ++G+ + D G Sbjct: 336 FFDERMAENMKLMMAKLSADPHAGH-----NMGNMDMGSMQSGAMDHDMHGARSSADAG- 389 Query: 437 PIIDYILTGNTSYPVSDNIVQVDAVD------QWTYWLIENDPEGPFSLPHPMHLHGHDF 490 P ++ LT ++ +D +D W W + +PHP H+HG F Sbjct: 390 PALE-ALTSGVEMAIAGKPFDMDRIDVEAKLGSWEIWDLTTK-----EMPHPFHIHGASF 443 Query: 491 LVLGRSPDVPAASQQRFVFDPAVDLARLNGDNPPRRDTTMLPAGGWLLLAFRTDNPGA-- 548 +L + P A Q + +DT ++ +L+ F + + Sbjct: 444 RILSLNGKAPPAHQSGW------------------KDTALIDGKAEILVHFDREAVKSHP 485 Query: 549 WLFHCHIAWHVSGGLSVDFL 568 ++FHCH+ H G+ F+ Sbjct: 486 FMFHCHVLEHEDVGMMAQFV 505 >3G5W-A nrPDB Length = 318 Score = 57.4 bits (137), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 55/223 (24%), Positives = 94/223 (42%), Gaps = 12/223 (5%) Query: 110 INGNIMGPNIVANWGDTVEVTVINNLVTNGTSIHWHGIHQKDTNLHDGANGVTECPIPPK 169 NG + P I GD V V V N+ T +IHWHG+ Q+ T DG T+ I P Sbjct: 27 FNGQVPAPLIHVMEGDDVTVNV-TNMTTLPHTIHWHGMLQRGTWQSDGVPHATQHAIEP- 84 Query: 170 GGQRTYRWRARQYGTSWYHSHFSAQYG---NGVVGTIQINGPASLPYDIDLGVFPITDYY 226 G TY+++A GT WYH H + G+ G + + LP + + DY Sbjct: 85 GDTFTYKFKAEPAGTMWYHCHVNVNEHVTMRGMWGPLIVEPKNPLPIEKTV----TKDYI 140 Query: 227 YRAADDLVHFTQNNAPPFSDNVLINGTAVNPNTGEGQYANVTLTPGKRHRLRILNTSTEN 286 +D + + + + +N + + + + G RLR++ Sbjct: 141 LMLSDWVSSWANKPGEGGIPGDVFDYYTINAKSFP-ETQPIRVKKGDVIRLRLIGAGDHV 199 Query: 287 HFQVSLVNHTMTVIAADMVPVNA-MTVDSLFLAVGQRYDVVID 328 H + H + D P++ + D++ + G+RYDV+++ Sbjct: 200 H-AIHTHGHISQIAFKDGFPLDKPIKGDTVLIGPGERYDVILN 241 Score = 33.5 bits (75), Expect = 0.27, Method: Compositional matrix adjust. Identities = 14/42 (33%), Positives = 21/42 (50%) Query: 521 DNPPRRDTTMLPAGGWLLLAFRTDNPGAWLFHCHIAWHVSGG 562 D P + DT ++ G + DNPG W+ H H+ H + G Sbjct: 220 DKPIKGDTVLIGPGERYDVILNMDNPGLWMIHDHVDTHTTNG 261 >5ZLM-A nrPDB Length = 513 Score = 57.0 bits (136), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 127/500 (25%), Positives = 186/500 (37%), Gaps = 106/500 (21%) Query: 111 NGNIMGPNIVANWGDTVEVTVINNLVTNGTSIHWHGIHQKDT-----------NLH---- 155 NG GP I + V V +NNL + H IH D+ +LH Sbjct: 52 NGLFPGPTIEVKRNENVYVKWMNNLPSTHFLPIDHTIHHSDSQHEEPEVKTVVHLHGGVT 111 Query: 156 -DGANGVTEC-------PIPPKGGQRTYRWRARQYGTS-WYHSHFSA----QYGNGVVGT 202 D ++G E P + Y + +Q G WYH H A G+VG Sbjct: 112 PDDSDGYPEAWFSKDFEQTGPYFKREVYHYPNQQRGAILWYHDHAMALTRLNVYAGLVGA 171 Query: 203 IQINGPA----SLP---YDIDLGVFPITDYYYRAADDLVHFTQNNAPPFSDNVLINGTAV 255 I+ P LP YD+ L ITD R ++ +AP L N + V Sbjct: 172 YIIHDPKEKRLKLPSDEYDVPLL---ITD---RTINEDGSLFYPSAPENPSPSLPNPSIV 225 Query: 256 NPNTGEGQYANVTLTP-----GKRHRLRILNTSTENHFQVSLVNH-TMTVIAAD--MVPV 307 GE N + P +++R R++N S + +SL N I +D ++P Sbjct: 226 PAFCGETILVNGKVWPYLEVEPRKYRFRVINASNTRTYNLSLDNGGDFIQIGSDGGLLP- 284 Query: 308 NAMTVDSLFLAVGQRYDVVIDASRAPDNYWFNVTFGGQAACGGSLNPHP-AAIFHYAGAP 366 ++ ++S LA +RYD++ID + ++ A CGG +NP A I + Sbjct: 285 RSVKLNSFSLAPAERYDIIIDFTAYEGE---SIILANSAGCGGDVNPETDANIMQFRVTK 341 Query: 367 GGLPTDEGTPPVDHQCLDTLDVRPVVPRSVPVNSFVKRPDNTLPVALDLTGTPLFVWKVN 426 DE P L P V +R N L L GT Sbjct: 342 PLAQKDESRKP------KYLASYPSVQH--------ERIQNIR--TLKLAGT-------- 377 Query: 427 GSDINVDWGKPIIDYILTGNTSYPVSDNIVQVDAVDQWTYWLIENDPEGPFSLPHPMHLH 486 ++G+P+ +L N + D + + V W I N G HP+HLH Sbjct: 378 ----QDEYGRPV---LLLNNKRW--HDPVTETPKVGTTEIWSIINPTRG----THPIHLH 424 Query: 487 GHDFLVLGRSPDVPAASQQRFVFDPAVDLARLNGDNPPR------RDTTMLPAGGWLLLA 540 F VL R P A Q+ + +L+ PP +DT AG L +A Sbjct: 425 LVSFRVLDRRPFDIARYQE------SGELSYTGPAVPPPPSEKGWKDTIQAHAGEVLRIA 478 Query: 541 FRTDNP--GAWLFHCHIAWH 558 T P G +++ CHI H Sbjct: 479 -ATFGPYSGRYVWCCHILEH 497 >2YAP-A nrPDB Length = 439 Score = 53.9 bits (128), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 65/257 (25%), Positives = 110/257 (42%), Gaps = 53/257 (20%) Query: 99 PDGVVKEKVMLIN--GNIMGPNIVANWGDTVEVTVINNLVTNGTSIHWHGIHQKDTNLHD 156 P + ++ L+ G+ GP + DTV +T+ N L T++HWHG+ Sbjct: 27 PLAIAGQRATLLTYGGSFPGPTLRVRPRDTVRLTLENRL-PEPTNLHWHGL--------- 76 Query: 157 GANGVTECPIPPK----------GGQRTYRWRARQ--YGTSWYHSHF----SAQYGNGVV 200 PI PK G TY + + GT WYH H + Q G++ Sbjct: 77 --------PISPKVDDPFLEIPPGESWTYEFTVPKELAGTFWYHPHLHGRVAPQLFAGLL 128 Query: 201 GTIQINGPA-SLP--YDIDLGVFPITDYYYRAADDLVHFTQN--NAPPFSDNVLINGTAV 255 G + + ++P + + + + D + H + N D VL+NG A+ Sbjct: 129 GALVVESSLDAIPELREAEEHLLVLKDLALQGGRPAPHTPMDWMNGKE-GDLVLVNG-AL 186 Query: 256 NPNTGEGQYANVTLTPGKRHRLRILNTSTENHFQVSLVNHTMTVIAADMVPVNA-MTVDS 314 P T Q A + RLR+LN S +++++L +H + +IAAD + + V Sbjct: 187 RP-TLVAQKATL--------RLRLLNASNARYYRLALQDHPLYLIAADGGFLEEPLEVSE 237 Query: 315 LFLAVGQRYDVVIDASR 331 L LA G+R +V++ + Sbjct: 238 LLLAPGERAEVLVRLRK 254 Score = 28.9 bits (63), Expect = 6.8, Method: Compositional matrix adjust. Identities = 27/97 (27%), Positives = 37/97 (38%), Gaps = 24/97 (24%) Query: 467 WLIENDPEGPFSLPHPMHLHGHDFLVLGRSPDVPAASQQRFVFDPAVDLARLNGDNPPRR 526 W +EN + + HP HLH H F VL + + F + D+ L R Sbjct: 360 WEVENQGD----MDHPFHLHVHPFQVL-------SVGGRPFPYRAWKDVVNLKAGEVAR- 407 Query: 527 DTTMLPAGGWLLLAFRTDNPGAWLFHCHIAWHVSGGL 563 LL+ R G +FHCHI H G+ Sbjct: 408 ----------LLVPLREK--GRTVFHCHIVEHEDRGM 432 >3ZX1-A nrPDB Length = 481 Score = 52.8 bits (125), Expect = 5e-07, Method: Compositional matrix adjust. Identities = 59/240 (24%), Positives = 89/240 (37%), Gaps = 47/240 (19%) Query: 111 NGNIMGPNIVANWGDTVEVTVINNLVTNGTSIHWHGIHQKDTNLHDGANGVTECPIPP-- 168 NG + P I GD +E+ V N L T+IHWHG+ P+PP Sbjct: 76 NGLVPAPKIEVFEGDKLEILVKNKL-KEATTIHWHGV-----------------PVPPDQ 117 Query: 169 ---------KGGQRTYRWRARQ--YGTSWYHSH----FSAQYGNGVVGTIQINGPASLPY 213 G +R YR+ Q GT WYH H S Q G+ G I Sbjct: 118 DGSPHDPILAGEERIYRFEIPQDSAGTYWYHPHPHYTASKQVFMGLAGAFVIKAKKDALS 177 Query: 214 DIDLGVFPITDYYYRAADDLVHFTQNNAPPFSDNVLINGTAVNPNTGEGQYA-NVTLTPG 272 + I+D D+ NN N +NG GQ+ + L Sbjct: 178 HLKEKDLMISDL---RLDENAQIPNNNL-----NDWLNGREGEFVLINGQFKPKIKLATN 229 Query: 273 KRHRLRILNTSTENHFQVSLVNHTMTVIAADMVPV-NAMTVDSLFLAVGQRYDVVIDASR 331 + R+RI N + + + + ++ D + + + LFL+ R +V+IDA + Sbjct: 230 E--RIRIYNATAARYLNLRIQGAKFILVGTDGGLIEKTIYKEELFLSPASRVEVLIDAPK 287 Score = 32.7 bits (73), Expect = 0.51, Method: Compositional matrix adjust. Identities = 22/90 (24%), Positives = 34/90 (37%), Gaps = 26/90 (28%) Query: 479 LPHPMHLHGHDFLVLGRSPDVPAASQQRFVFDPAVDLARLNG-----DNPPRRDTTMLPA 533 + HP H+HG F ++ ++LNG + RDT + Sbjct: 405 MDHPFHIHGTQFELIS---------------------SKLNGKVQKAEFRALRDTINVRP 443 Query: 534 GGWLLLAFRTDNPGAWLFHCHIAWHVSGGL 563 L L + D G ++HCHI H G+ Sbjct: 444 NEELRLRMKQDFKGLRMYHCHILEHEDLGM 473 >3GDC-A nrPDB Length = 288 Score = 45.8 bits (107), Expect = 5e-05, Method: Compositional matrix adjust. Identities = 38/135 (28%), Positives = 55/135 (40%), Gaps = 8/135 (5%) Query: 111 NGNIMGPNIVANWGDTVEVTVINNLVTNGTSIHWHGIHQKDTNLHDGANGVTECPIPPKG 170 NG I GP + A GD + + N + +IH+HG+H+ DG G+ I P G Sbjct: 60 NGRIPGPTLWAREGDALRIH-FTNAGAHPHTIHFHGVHRATM---DGTPGIGAGSIAP-G 114 Query: 171 GQRTYRWRARQYGTSWYHSH---FSAQYGNGVVGTIQINGPASLPYDIDLGVFPITDYYY 227 TY + A +GT YH H + G+ G + P D V + Y Sbjct: 115 QSFTYEFDATPFGTHLYHCHQSPLAPHIAKGLYGGFIVEPKEGRPPADDEMVMVMNGYNT 174 Query: 228 RAADDLVHFTQNNAP 242 DD ++ N P Sbjct: 175 DGGDDNEFYSVNGLP 189 >3GYR-A nrPDB Length = 612 Score = 39.3 bits (90), Expect = 0.005, Method: Compositional matrix adjust. Identities = 33/121 (27%), Positives = 50/121 (41%), Gaps = 18/121 (14%) Query: 462 DQWTYWLIENDPEGPFSLPHPMHLHGHDFLVLGRSPDVPAASQQRFVFDPAVDLARLNGD 521 +QWT+ + + HPMH+H DF VLGR D AS RL+ D Sbjct: 482 EQWTFLNLS-------PILHPMHIHLADFQVLGR--DAYDASGFDLALGGTRTPVRLDPD 532 Query: 522 NP--------PRRDTTMLPAGGWLLLAFRTDNP-GAWLFHCHIAWHVSGGLSVDFLERPA 572 P +D +P L + + D G +++HCH+ H G+ F+ P Sbjct: 533 TPVPLAPNELGHKDVFQVPGPQGLRVMGKFDGAYGRFMYHCHLLEHEDMGMMRPFVVMPP 592 Query: 573 D 573 + Sbjct: 593 E 593 >3T9W-A nrPDB Length = 299 Score = 38.5 bits (88), Expect = 0.008, Method: Compositional matrix adjust. Identities = 26/93 (27%), Positives = 40/93 (43%), Gaps = 15/93 (16%) Query: 481 HPMHLHGHDFLVLGRSPDVPAASQQRFVFDPAVDLARLNGDNPPRRDTTMLPAGGWLLLA 540 H HLHGH +L + + P +D+ LN + G+ ++A Sbjct: 212 HTFHLHGHRWL-----DNRTGMRTSEYDPSPLIDIKDLNPG----------VSFGFQVIA 256 Query: 541 FRTDNPGAWLFHCHIAWHVSGGLSVDFLERPAD 573 PG W++HCH+ H G++ FL R AD Sbjct: 257 GEGVGPGMWMYHCHVQNHSDMGMAGMFLVRNAD 289 >2UXV-A nrPDB Length = 451 Score = 37.7 bits (86), Expect = 0.015, Method: Compositional matrix adjust. Identities = 62/245 (25%), Positives = 103/245 (42%), Gaps = 40/245 (16%) Query: 104 KEKVMLINGNIMGPNIVANWGDTVEVTVINNLVTNGTSIHWHGIHQKDTNLHDGANGVTE 163 + V ING +GP I GD V++ + +N +T S+ G+ + A ++ Sbjct: 37 RASVWGINGRYLGPTIRVWKGDDVKL-IYSNRLTENVSMTVAGLQVPGPLMGGPARMMSP 95 Query: 164 ----CPIPPKGGQRTYRWRARQYGTSWYHSH----FSAQYGNGVVGT--IQINGPASLPY 213 P+ P + T WYH++ + Q NG+ G ++ SLP Sbjct: 96 NADWAPVLPI---------RQNAATLWYHANTPNRTAQQVYNGLAGMWLVEDEVSKSLPI 146 Query: 214 DIDLGV--FPITDYYYRAADDLVHFTQNNAPP----FSDNVLINGTAVNPNTGEGQYANV 267 GV FP+ R D + N P D +L+NG Q V Sbjct: 147 PNHYGVDDFPVIIQDKRL--DNFGTPEYNEPGSGGFVGDTLLVNGV---------QSPYV 195 Query: 268 TLTPGKRHRLRILNTSTENHFQVSLVN-HTMTVIAADMVPVNA-MTVDSLFLAVGQRYDV 325 ++ G RLR+LN S +Q+ + + + VI+ D + A ++V L LA G+R ++ Sbjct: 196 EVSRGW-VRLRLLNASNSRRYQLQMNDGRPLHVISGDQGFLPAPVSVKQLSLAPGERREI 254 Query: 326 VIDAS 330 ++D S Sbjct: 255 LVDMS 259 >2VMJ-A nrPDB Length = 329 Score = 37.4 bits (85), Expect = 0.022, Method: Compositional matrix adjust. Identities = 27/83 (32%), Positives = 41/83 (49%), Gaps = 7/83 (8%) Query: 106 KVMLINGNIMGPNIVANWGDTVEVTVINNLVTNGTSIHWHGIHQKDTNLHDGANGVTECP 165 + M NG++ GP +V + GD V++T++N TN H D + GA G + Sbjct: 55 QAMTFNGSMPGPTLVVHEGDYVQLTLVNP-ATNAMP------HNVDFHGATGALGGAKLT 107 Query: 166 IPPKGGQRTYRWRARQYGTSWYH 188 G Q T R++A + GT YH Sbjct: 108 NVNPGEQATLRFKADRSGTFVYH 130 >4NB7-A nrPDB Length = 343 Score = 34.3 bits (77), Expect = 0.16, Method: Compositional matrix adjust. Identities = 22/71 (30%), Positives = 34/71 (47%), Gaps = 5/71 (7%) Query: 113 NIMGPNIVANWGDTVEVTVINNLVTNGTSIHWHGIHQKDTNLHDGANGVTECPIPPKGGQ 172 ++ GP I N GDT+ + N + S+H HG+ D + + + + P GG Sbjct: 73 SVPGPLIEVNEGDTLHIEFTNTMDVR-ASLHVHGL---DYEISSDGTAMNKSDVEP-GGT 127 Query: 173 RTYRWRARQYG 183 RTY WR + G Sbjct: 128 RTYTWRTHKPG 138 Score = 32.7 bits (73), Expect = 0.51, Method: Compositional matrix adjust. Identities = 13/39 (33%), Positives = 21/39 (53%) Query: 535 GWLLLAFRTDNPGAWLFHCHIAWHVSGGLSVDFLERPAD 573 G+ ++A GAW++HCH+ H G+ FL + D Sbjct: 270 GFQIIAGEGVGAGAWMYHCHVQSHSDMGMVGLFLVKKPD 308 >4GXF-A nrPDB Length = 279 Score = 33.9 bits (76), Expect = 0.20, Method: Compositional matrix adjust. Identities = 22/71 (30%), Positives = 34/71 (47%), Gaps = 5/71 (7%) Query: 113 NIMGPNIVANWGDTVEVTVINNLVTNGTSIHWHGIHQKDTNLHDGANGVTECPIPPKGGQ 172 ++ GP I N GDT+ + N + S+H HG+ D + + + + P GG Sbjct: 36 SVPGPLIEVNEGDTLHIEFTNTMDVR-ASLHVHGL---DFEISSDGTAMNKSDVEP-GGT 90 Query: 173 RTYRWRARQYG 183 RTY WR + G Sbjct: 91 RTYTWRTHKPG 101 Score = 32.3 bits (72), Expect = 0.55, Method: Compositional matrix adjust. Identities = 13/39 (33%), Positives = 21/39 (53%) Query: 535 GWLLLAFRTDNPGAWLFHCHIAWHVSGGLSVDFLERPAD 573 G+ ++A GAW++HCH+ H G+ FL + D Sbjct: 233 GFQIIAGEGVGAGAWMYHCHVQSHSDMGMVGLFLVKKPD 271 >4WTQ-A nrPDB Length = 293 Score = 33.1 bits (74), Expect = 0.34, Method: Compositional matrix adjust. Identities = 14/39 (35%), Positives = 21/39 (53%) Query: 535 GWLLLAFRTDNPGAWLFHCHIAWHVSGGLSVDFLERPAD 573 G+ ++A GAW++HCH+ H GL FL + D Sbjct: 235 GFQVIAGEGVGAGAWMYHCHVQSHSDMGLVGLFLVKKTD 273 Score = 31.2 bits (69), Expect = 1.3, Method: Compositional matrix adjust. Identities = 24/79 (30%), Positives = 35/79 (44%), Gaps = 5/79 (6%) Query: 100 DGVVKEKVMLINGNIMGPNIVANWGDTVEVTVINNLVTNGTSIHWHGIHQKDTNLHDGAN 159 DG + + I GP I N GDT+ + N + S+H HG+ D + Sbjct: 25 DGQMGYGLEKGRATIPGPLIELNEGDTLHIEFENTMDVR-ASLHVHGL---DYEVSSDGT 80 Query: 160 GVTECPIPPKGGQRTYRWR 178 + + + P GG RTY WR Sbjct: 81 TLNKSDVEP-GGTRTYTWR 98 >5TB7-A nrPDB Length = 337 Score = 33.1 bits (74), Expect = 0.40, Method: Compositional matrix adjust. Identities = 17/57 (29%), Positives = 29/57 (50%), Gaps = 5/57 (8%) Query: 528 TTMLPAGGWLLLAFRTDNPGAWLFHCHIAWHVS-----GGLSVDFLERPADLRQRIS 579 +T++PAGG ++ F+ D PG + H + G L V+ E P + Q++S Sbjct: 263 STIVPAGGSAIVEFKVDIPGNYTLVDHSIFRAFNKGALGQLKVEGAENPEIMTQKLS 319 >4N8U-A nrPDB Length = 281 Score = 32.7 bits (73), Expect = 0.42, Method: Compositional matrix adjust. Identities = 24/97 (24%), Positives = 36/97 (37%), Gaps = 23/97 (23%) Query: 481 HPMHLHGH----DFLVLGRSPDVPAASQQRFVFDPAVDLARLNGDNPPRRDTTMLPAGGW 536 H H+HGH + L PD P+ + PA G+ Sbjct: 196 HTFHMHGHRWADNRTGLLTGPDDPSQVIDNKIVGPADSF-------------------GF 236 Query: 537 LLLAFRTDNPGAWLFHCHIAWHVSGGLSVDFLERPAD 573 ++A GAW++HCH+ H G+ FL + D Sbjct: 237 QVIAGEGVGAGAWMYHCHVQSHSDMGMVGLFLVKKKD 273 Score = 32.3 bits (72), Expect = 0.69, Method: Compositional matrix adjust. Identities = 26/65 (40%), Positives = 33/65 (50%), Gaps = 5/65 (7%) Query: 114 IMGPNIVANWGDTVEVTVINNLVTNGTSIHWHGIHQKDTNLHDGANGVTECPIPPKGGQR 173 I GP I N GDT + V N L S+H HG+ + T+ DG + + P GG R Sbjct: 39 IPGPLIELNEGDTAHIEVENTLDVP-ASLHVHGLDYEITS--DGTK-LNRSDVEP-GGTR 93 Query: 174 TYRWR 178 TY WR Sbjct: 94 TYTWR 98 >5LHL-A nrPDB Length = 322 Score = 32.7 bits (73), Expect = 0.51, Method: Compositional matrix adjust. Identities = 13/39 (33%), Positives = 21/39 (53%) Query: 535 GWLLLAFRTDNPGAWLFHCHIAWHVSGGLSVDFLERPAD 573 G+ ++A GAW++HCH+ H G+ FL + D Sbjct: 271 GFQIIAGEGVGAGAWMYHCHVQSHSDMGMVGLFLVKKPD 309 Score = 31.2 bits (69), Expect = 1.3, Method: Compositional matrix adjust. Identities = 24/71 (33%), Positives = 33/71 (46%), Gaps = 5/71 (7%) Query: 113 NIMGPNIVANWGDTVEVTVINNLVTNGTSIHWHGIHQKDTNLHDGANGVTECPIPPKGGQ 172 +I GP I N GDT+ V N + S+H HG+ D + + + P GG Sbjct: 74 SIPGPLIELNEGDTLHVEFENTMDVP-VSLHVHGL---DYEISSDGTKQNKSHVEP-GGT 128 Query: 173 RTYRWRARQYG 183 RTY WR + G Sbjct: 129 RTYTWRTHEPG 139 >3TBB-A nrPDB Length = 313 Score = 32.3 bits (72), Expect = 0.67, Method: Compositional matrix adjust. Identities = 24/97 (24%), Positives = 36/97 (37%), Gaps = 23/97 (23%) Query: 481 HPMHLHGH----DFLVLGRSPDVPAASQQRFVFDPAVDLARLNGDNPPRRDTTMLPAGGW 536 H HLHGH + + PD P+ + PA G+ Sbjct: 196 HTFHLHGHRWADNRTGMLTGPDDPSQVIDNKICGPADSF-------------------GF 236 Query: 537 LLLAFRTDNPGAWLFHCHIAWHVSGGLSVDFLERPAD 573 ++A GAW++HCH+ H G+ FL + D Sbjct: 237 QVIAGEGVGAGAWMYHCHVQSHSDMGMVGLFLVKKPD 273 Score = 30.0 bits (66), Expect = 3.1, Method: Compositional matrix adjust. Identities = 29/101 (28%), Positives = 42/101 (41%), Gaps = 19/101 (18%) Query: 114 IMGPNIVANWGDTVEVTVINNLVTNGTSIHWHGIHQKDTNLHDGANGVTECPIPPKGGQR 173 I GP I N GDT+ + N + S+H HG+ D + + + P GG R Sbjct: 39 IPGPLIELNEGDTLHIEFENTMDVP-VSLHVHGL---DYEISSDGTKQSRSDVEP-GGTR 93 Query: 174 TYRWR----ARQYGTSW---------YHSH-FSAQYGNGVV 200 TY WR R+ +W YH H ++G G + Sbjct: 94 TYTWRTHVPGRRADGTWRAGSAGYWHYHDHVVGTEHGTGGI 134 >6IQY-A nrPDB Length = 538 Score = 32.0 bits (71), Expect = 0.81, Method: Compositional matrix adjust. Identities = 104/467 (22%), Positives = 164/467 (35%), Gaps = 96/467 (20%) Query: 116 GPNIVANWGDTVEVTVINNLVTNGTSIHWHGIHQKDTNLHDG-ANGVTECPIPPKGGQRT 174 GP G V INN S+H HG + DG A +TE G + Sbjct: 72 GPTFQVPRGVETVVRFINN-AEAPNSVHLHGSFSRAA--FDGWAEDITE-----PGSFKD 123 Query: 175 YRWRARQYG-TSWYHSH---FSAQYG-NGVVGTIQINGPASLPYDIDLGV------FPIT 223 Y + RQ T WYH H +A+ G G + PA ++ G +T Sbjct: 124 YYYPNRQSARTLWYHDHAMHITAENAYRGQAGLYMLTDPAEDALNLPSGYGEFDIPMILT 183 Query: 224 DYYYRAADDLVHFTQNNAPPFSDNVLINGTAVNPNTGEGQYANVTLTPGKRHRLRILNTS 283 Y A +LV + D + +NG + NV +++R R L+ + Sbjct: 184 SKQYTANGNLVTTNGELNSFWGDVIHVNGQP-------WPFKNVE---PRKYRFRFLDAA 233 Query: 284 TENHFQVSLVNHT-------MTVIAADM-VPVNAMTVDSLFLAVGQRYDVVIDASRAPDN 335 F + + VIA+D + + L++++ +RY+VV D S Sbjct: 234 VSRSFGLYFADTDAIDTRLPFKVIASDSGLLEHPADTSLLYISMAERYEVVFDFS----- 288 Query: 336 YWFNVTFGGQAACGGSLNPHPAAIFHYAGAPGGLPTDEGTPPVDHQCLDTLDVRPVVPRS 395 + G+ +L G+ GG+ TD D+ D Sbjct: 289 -----DYAGKTIELRNL----------GGSIGGIGTD-----TDYDNTDK---------- 318 Query: 396 VPVNSFVKRPDNTLP----VALDLTGTPLFVWKVNGSDINVDWGKPIIDYILTGNTSYPV 451 V FV D T P V +L P F + +G+ + + G V Sbjct: 319 --VMRFVVADDTTQPDTSVVPANLRDVP-FPSPTTNTPRQFRFGRTGPTWTINGVAFADV 375 Query: 452 SDNIVQVDAVDQWTYWLIENDPEGPFSLPHPMHLHGHDFLVLGRSPDVPAASQQRFVFDP 511 + ++ V W + N G HP+H+H DF V+ R+ A + + Sbjct: 376 QNRLLANVPVGTVERWELINAGNG---WTHPIHIHLVDFKVISRTSGNNARTVMPYE-SG 431 Query: 512 AVDLARLNGDNPPRRDTTMLPAGGWLLLAFRTDNPGAWLFHCHIAWH 558 D+ L RR+T ++ A PG ++FHCH H Sbjct: 432 LKDVVWLG-----RRETVVVE-------AHYAPFPGVYMFHCHNLIH 466 >2ZOO-A nrPDB Length = 442 Score = 31.6 bits (70), Expect = 1.2, Method: Compositional matrix adjust. Identities = 15/48 (31%), Positives = 27/48 (56%), Gaps = 2/48 (4%) Query: 528 TTMLPAGGWLLLAFRTDNPGAWLFHCHIAWHV--SGGLSVDFLERPAD 573 TT++PAGG ++ F+ + PG ++ H + G L++ +E P D Sbjct: 253 TTLIPAGGAAIVEFKVEVPGTFILVDHSIFRAFNKGALAMLKVEGPDD 300 >5AKR-A nrPDB Length = 378 Score = 31.2 bits (69), Expect = 1.6, Method: Compositional matrix adjust. Identities = 12/39 (30%), Positives = 21/39 (53%), Gaps = 4/39 (10%) Query: 539 LAFRTDNPGAWLFHC----HIAWHVSGGLSVDFLERPAD 573 L F+ PG +++HC + WHV+ G++ + P D Sbjct: 160 LRFKATKPGVFVYHCAPEGMVPWHVTSGMNGAIMVLPRD 198 >1NDS-A nrPDB Length = 330 Score = 30.8 bits (68), Expect = 1.8, Method: Compositional matrix adjust. Identities = 13/42 (30%), Positives = 23/42 (54%) Query: 92 EVDNWMGPDGVVKEKVMLINGNIMGPNIVANWGDTVEVTVIN 133 E + D + M NG++ GP +V + GD +E+T++N Sbjct: 36 EEKKMVADDDGTTAQAMTFNGSVPGPTLVVHEGDYIELTLVN 77 >2Y1A-A nrPDB Length = 340 Score = 30.8 bits (68), Expect = 1.9, Method: Compositional matrix adjust. Identities = 12/39 (30%), Positives = 21/39 (53%), Gaps = 4/39 (10%) Query: 539 LAFRTDNPGAWLFHC----HIAWHVSGGLSVDFLERPAD 573 L F+ PG +++HC + WHV+ G++ + P D Sbjct: 122 LRFKATKPGVFVYHCAPEGMVPWHVTSGMNGAIMVLPRD 160 >4KNS-A nrPDB Length = 285 Score = 30.8 bits (68), Expect = 2.0, Method: Compositional matrix adjust. Identities = 43/180 (23%), Positives = 66/180 (36%), Gaps = 20/180 (11%) Query: 110 INGNIMGPNIVANWGDTVEVTVINNLVTNGTSIHWHGIHQKDTNLHDGANGVTECPIPPK 169 +G + GP + GDTVE T+IN+ N + H H ++ V + Sbjct: 28 FDGKVPGPVVRVTEGDTVEFTLIND--KNSKNSHSMDFHAARLDV------VEDFESIKP 79 Query: 170 GGQRTYRWRARQYGTSWYHSH---FSAQYGNGVVGTIQIN--GPASLPYDIDLGVFPITD 224 G + Y + A G +YH G+ G I ++ +LP D I Sbjct: 80 GETKKYTFTADNPGVFFYHCGSDPMIQHIARGMYGVIIVDPKDANALP-KADREYVLIQA 138 Query: 225 YYYRAADDLVHFTQNNAPPFSDNVLINGTAVNPNTGEGQYAN--VTLTPGKRHRLRILNT 282 +Y DD QN NV+ NG + A + PG+R R+ +N Sbjct: 139 EHYENPDDKTAMMQNKW----SNVVFNGGVFKYDPVHDSEATSWLQAKPGERVRIYFVNA 194 >3X1F-A nrPDB Length = 352 Score = 30.0 bits (66), Expect = 2.7, Method: Compositional matrix adjust. Identities = 39/153 (25%), Positives = 62/153 (40%), Gaps = 19/153 (12%) Query: 110 INGNIMGPNIVANWGDTVEVTVINNLVTNGTSIHWHGIHQKDTNLHDGANGVTECPIPPK 169 NG GP +V N GDT+ T+ N S+ +H +H + +P K Sbjct: 94 FNGQAPGPLVVVNEGDTIHFTLKNMDPVVPHSMDFHAVHASPSKDFIDV-------MPNK 146 Query: 170 GGQRTYRWRARQYGTSWYHSHFS---AQYGNGVVGTIQINGPASLPYD--IDLGVFPITD 224 G T+ + A + G YH NG+ G I + P D +D I + Sbjct: 147 SG--TFTYPANKPGVFMYHCGTKPVLQHIANGMHGVIIVKPKNGYPTDKEVDREYVLIQN 204 Query: 225 YYYRAADDLVHFTQNNAPPFSDNVLINGTAVNP 257 +Y+ +D+ F QN P + V+ + A+ P Sbjct: 205 EWYK-YNDMNDF-QNGVPSY---VVFSSKALKP 232 >3WIA-A nrPDB Length = 287 Score = 30.0 bits (66), Expect = 3.2, Method: Compositional matrix adjust. Identities = 40/157 (25%), Positives = 63/157 (40%), Gaps = 19/157 (12%) Query: 106 KVMLINGNIMGPNIVANWGDTVEVTVINNLVTNGTSIHWHGIHQKDTNLHDGANGVTECP 165 K NG GP +V N GDT+ T+ N S+ +H +H + Sbjct: 25 KAWTFNGQAPGPLVVVNEGDTIHFTLKNMDPVVPHSMDFHAVHASPSKDFIDV------- 77 Query: 166 IPPKGGQRTYRWRARQYGTSWYHSHFS---AQYGNGVVGTIQINGPASLPYD--IDLGVF 220 +P K G T+ + A + G YH NG+ G I + P D +D Sbjct: 78 MPNKSG--TFTYPANKPGVFMYHCGTKPVLQHIANGMHGVIIVKPKNGYPTDKEVDREYV 135 Query: 221 PITDYYYRAADDLVHFTQNNAPPFSDNVLINGTAVNP 257 I + +Y+ +D+ F QN P + V+ + A+ P Sbjct: 136 LIQNEWYK-YNDMNDF-QNGVPSY---VVFSSKALKP 167 >1SDD-A nrPDB Length = 306 Score = 29.6 bits (65), Expect = 3.9, Method: Compositional matrix adjust. Identities = 39/171 (22%), Positives = 71/171 (41%), Gaps = 25/171 (14%) Query: 104 KEKVMLINGNIMGPNIVANWGDTVEVTVINNLVTNGTSIHWHGIHQKDTNLHDGANGVTE 163 KEK ++GP + A GD ++V N SIH GI K + +GA+ ++ Sbjct: 47 KEKPQSRTSGLLGPTLYAEVGDIMKVH-FKNKAHKPLSIHAQGI--KYSKFSEGAS-YSD 102 Query: 164 CPIPPK--------GGQRTYRWRARQYG----------TSWYHSHFS--AQYGNGVVGTI 203 +P + G + TY W ++ T Y+S+ + + +G++G + Sbjct: 103 HTLPMEKMDDAVAPGQEYTYEWIISEHSGPTHDDPPCLTHIYYSYVNLVEDFNSGLIGPL 162 Query: 204 QINGPASLPYDIDLGVFPITDYYYRAA-DDLVHFTQNNAPPFSDNVLINGT 253 I +L D +F A D+ + Q ++ ++ N +NGT Sbjct: 163 LICKKGTLTEDGTQKMFEKQHVLMFAVFDESKSWNQTSSLMYTVNGYVNGT 213 >1Z01-A nrPDB Length = 446 Score = 29.3 bits (64), Expect = 5.0, Method: Compositional matrix adjust. Identities = 21/66 (31%), Positives = 28/66 (42%), Gaps = 9/66 (13%) Query: 50 REPTCNTPSNRACWSDGFDINTDYEVSTPDTGVTQSYVFNLTEVDNWMGPDGVVKEKVML 109 +PTC T S +CW GF + +TG + V N D +G GV V Sbjct: 93 EKPTCFTKSTISCWYHGFTFDL-------ETGKLVTIVANPE--DKLIGTTGVTTYPVHE 143 Query: 110 INGNIM 115 +NG I Sbjct: 144 VNGMIF 149 >1N70-A nrPDB Length = 334 Score = 29.3 bits (64), Expect = 5.0, Method: Compositional matrix adjust. Identities = 14/45 (31%), Positives = 23/45 (51%), Gaps = 5/45 (11%) Query: 534 GGWLLLAFRTDNPGAWLFHC-----HIAWHVSGGLSVDFLERPAD 573 G ++L F+ GA+++HC I WHV G++ + P D Sbjct: 108 GEKVVLRFKATRAGAFVYHCAPGGPMIPWHVVSGMAGCIMVLPRD 152 Score = 28.9 bits (63), Expect = 7.9, Method: Compositional matrix adjust. Identities = 12/28 (42%), Positives = 20/28 (71%) Query: 106 KVMLINGNIMGPNIVANWGDTVEVTVIN 133 + M +G+I GP ++ + GD VE+T+IN Sbjct: 51 QAMTFDGSIPGPLMIVHEGDYVELTLIN 78 >1AS8-A nrPDB Length = 343 Score = 29.3 bits (64), Expect = 5.7, Method: Compositional matrix adjust. Identities = 12/44 (27%), Positives = 22/44 (50%), Gaps = 4/44 (9%) Query: 534 GGWLLLAFRTDNPGAWLFHC----HIAWHVSGGLSVDFLERPAD 573 G +L F+ PG +++HC + WHV G++ + P + Sbjct: 120 GEKTILRFKATKPGVFVYHCAPPGMVPWHVVSGMNGAIMVLPRE 163 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 3QPK-A nrPDB 759 0.0 3PPS-A nrPDB 744 0.0 6F5K-A nrPDB 707 0.0 3SQR-A nrPDB 559 e-159 2XYB-A nrPDB 550 e-157 5NQ7-A nrPDB 546 e-156 5NQ8-A nrPDB 545 e-155 3X1B-A nrPDB 543 e-155 3V9C-A nrPDB 542 e-154 1KYA-A nrPDB 540 e-154 4A2F-A nrPDB 537 e-153 5MIA-A nrPDB 536 e-152 1GYC-A nrPDB 536 e-152 2QT6-A nrPDB 532 e-151 4JHU-A nrPDB 531 e-151 2H5U-A nrPDB 525 e-149 3KW7-A nrPDB 522 e-148 1V10-A nrPDB 522 e-148 3T6Z-A nrPDB 519 e-147 5EHF-A nrPDB 515 e-146 5Z1X-A nrPDB 514 e-146 2HZH-A nrPDB 510 e-144 5LM8-A nrPDB 494 e-140 1HFU-A nrPDB 490 e-139 1ZPU-A nrPDB 405 e-113 1ASO-A nrPDB 363 e-100 4F7K-A nrPDB 301 6e-82 6EVG-A nrPDB 294 1e-79 5B7E-A nrPDB 289 3e-78 5ZLM-A nrPDB 279 3e-75 2YXV-A nrPDB 269 3e-72 3AW5-A nrPDB 264 1e-70 4E9V-A nrPDB 243 1e-64 3G5W-A nrPDB 225 7e-59 2YAP-A nrPDB 223 1e-58 3ZX1-A nrPDB 219 3e-57 3GDC-A nrPDB 140 2e-33 Sequences not found previously or not previously below threshold: 6IQY-A nrPDB 144 7e-35 3GYR-A nrPDB 138 5e-33 2UXV-A nrPDB 134 1e-31 5OCB-A nrPDB 87 3e-17 3X1F-A nrPDB 81 1e-15 4KNS-A nrPDB 81 1e-15 3WIA-A nrPDB 81 2e-15 5TB7-A nrPDB 80 3e-15 2ZOO-A nrPDB 77 3e-14 6HBE-A nrPDB 68 2e-11 2DV6-A nrPDB 63 5e-10 4NB7-A nrPDB 63 5e-10 4GXF-A nrPDB 62 7e-10 4N8U-A nrPDB 61 1e-09 2VMJ-A nrPDB 61 2e-09 4WTQ-A nrPDB 60 3e-09 5LHL-A nrPDB 59 5e-09 3TBB-A nrPDB 57 3e-08 1NDS-A nrPDB 54 2e-07 1N70-A nrPDB 53 4e-07 1SDD-B nrPDB 52 7e-07 3T9W-A nrPDB 51 1e-06 5AKR-A nrPDB 50 2e-06 2Y1A-A nrPDB 50 3e-06 1AS8-A nrPDB 47 2e-05 4BDV-A nrPDB 43 4e-04 2IWK-A nrPDB 37 0.030 1QNI-A nrPDB 36 0.039 4BDV-B nrPDB 36 0.055 2R7E-B nrPDB 36 0.072 5K8D-B nrPDB 35 0.12 3SBP-A nrPDB 34 0.16 1FWX-A nrPDB 34 0.20 1QHQ-A nrPDB 34 0.22 2RAC-A nrPDB 32 1.00 1CUR-A nrPDB 31 1.1 4DKN-A nrPDB 31 1.2 1Z01-A nrPDB 31 1.3 2AAN-A nrPDB 31 1.5 1FSK-B nrPDB 31 1.6 1OGO-X nrPDB 31 2.2 4H1O-A nrPDB 30 3.2 2CAK-A nrPDB 29 4.2 5B5M-H nrPDB 29 5.8 >3QPK-A nrPDB Length = 559 Score = 759 bits (1959), Expect = 0.0, Method: Composition-based stats. Identities = 559/559 (100%), Positives = 559/559 (100%) Query: 51 EPTCNTPSNRACWSDGFDINTDYEVSTPDTGVTQSYVFNLTEVDNWMGPDGVVKEKVMLI 110 EPTCNTPSNRACWSDGFDINTDYEVSTPDTGVTQSYVFNLTEVDNWMGPDGVVKEKVMLI Sbjct: 1 EPTCNTPSNRACWSDGFDINTDYEVSTPDTGVTQSYVFNLTEVDNWMGPDGVVKEKVMLI 60 Query: 111 NGNIMGPNIVANWGDTVEVTVINNLVTNGTSIHWHGIHQKDTNLHDGANGVTECPIPPKG 170 NGNIMGPNIVANWGDTVEVTVINNLVTNGTSIHWHGIHQKDTNLHDGANGVTECPIPPKG Sbjct: 61 NGNIMGPNIVANWGDTVEVTVINNLVTNGTSIHWHGIHQKDTNLHDGANGVTECPIPPKG 120 Query: 171 GQRTYRWRARQYGTSWYHSHFSAQYGNGVVGTIQINGPASLPYDIDLGVFPITDYYYRAA 230 GQRTYRWRARQYGTSWYHSHFSAQYGNGVVGTIQINGPASLPYDIDLGVFPITDYYYRAA Sbjct: 121 GQRTYRWRARQYGTSWYHSHFSAQYGNGVVGTIQINGPASLPYDIDLGVFPITDYYYRAA 180 Query: 231 DDLVHFTQNNAPPFSDNVLINGTAVNPNTGEGQYANVTLTPGKRHRLRILNTSTENHFQV 290 DDLVHFTQNNAPPFSDNVLINGTAVNPNTGEGQYANVTLTPGKRHRLRILNTSTENHFQV Sbjct: 181 DDLVHFTQNNAPPFSDNVLINGTAVNPNTGEGQYANVTLTPGKRHRLRILNTSTENHFQV 240 Query: 291 SLVNHTMTVIAADMVPVNAMTVDSLFLAVGQRYDVVIDASRAPDNYWFNVTFGGQAACGG 350 SLVNHTMTVIAADMVPVNAMTVDSLFLAVGQRYDVVIDASRAPDNYWFNVTFGGQAACGG Sbjct: 241 SLVNHTMTVIAADMVPVNAMTVDSLFLAVGQRYDVVIDASRAPDNYWFNVTFGGQAACGG 300 Query: 351 SLNPHPAAIFHYAGAPGGLPTDEGTPPVDHQCLDTLDVRPVVPRSVPVNSFVKRPDNTLP 410 SLNPHPAAIFHYAGAPGGLPTDEGTPPVDHQCLDTLDVRPVVPRSVPVNSFVKRPDNTLP Sbjct: 301 SLNPHPAAIFHYAGAPGGLPTDEGTPPVDHQCLDTLDVRPVVPRSVPVNSFVKRPDNTLP 360 Query: 411 VALDLTGTPLFVWKVNGSDINVDWGKPIIDYILTGNTSYPVSDNIVQVDAVDQWTYWLIE 470 VALDLTGTPLFVWKVNGSDINVDWGKPIIDYILTGNTSYPVSDNIVQVDAVDQWTYWLIE Sbjct: 361 VALDLTGTPLFVWKVNGSDINVDWGKPIIDYILTGNTSYPVSDNIVQVDAVDQWTYWLIE 420 Query: 471 NDPEGPFSLPHPMHLHGHDFLVLGRSPDVPAASQQRFVFDPAVDLARLNGDNPPRRDTTM 530 NDPEGPFSLPHPMHLHGHDFLVLGRSPDVPAASQQRFVFDPAVDLARLNGDNPPRRDTTM Sbjct: 421 NDPEGPFSLPHPMHLHGHDFLVLGRSPDVPAASQQRFVFDPAVDLARLNGDNPPRRDTTM 480 Query: 531 LPAGGWLLLAFRTDNPGAWLFHCHIAWHVSGGLSVDFLERPADLRQRISQEDEDDFNRVC 590 LPAGGWLLLAFRTDNPGAWLFHCHIAWHVSGGLSVDFLERPADLRQRISQEDEDDFNRVC Sbjct: 481 LPAGGWLLLAFRTDNPGAWLFHCHIAWHVSGGLSVDFLERPADLRQRISQEDEDDFNRVC 540 Query: 591 DEWRAYWPTNPYPKIDSGL 609 DEWRAYWPTNPYPKIDSGL Sbjct: 541 DEWRAYWPTNPYPKIDSGL 559 >3PPS-A nrPDB Length = 604 Score = 744 bits (1920), Expect = 0.0, Method: Composition-based stats. Identities = 447/614 (72%), Positives = 506/614 (82%), Gaps = 15/614 (2%) Query: 1 MKTFTSALALVVGMLAPGAVVAAPPSTPAQRDLVELREARQEGGKDLRPREPTCNTPSNR 60 MK++ +A+AL+VG+L+P A A P+ P QRD++++ EARQ G PTCNTPSNR Sbjct: 1 MKSWAAAVALMVGILSPHAAAAP-PANPVQRDMLQVLEARQSG--------PTCNTPSNR 51 Query: 61 ACWSDGFDINTDYEVSTPDTGVTQSYVFNLTEVDNWMGPDGVVKEKVMLINGNIMGPNIV 120 ACW++GFDINTDYEVSTP+TG T +Y LTE +NW+GPDGV+K VML+N I+GP I Sbjct: 52 ACWTNGFDINTDYEVSTPNTGRTVAYQLTLTEKENWIGPDGVLKNVVMLVNDKIIGPTIR 111 Query: 121 ANWGDTVEVTVINNLVTNGTSIHWHGIHQKDTNLHDGANGVTECPIPPKGGQRTYRWRAR 180 ANWGD +EVTVINNL TNGTS+HWHG+ Q +DGANGVTECPIPPKGG++TY++RA Sbjct: 112 ANWGDNIEVTVINNLKTNGTSMHWHGLRQLGNVFNDGANGVTECPIPPKGGRKTYKFRAT 171 Query: 181 QYGTSWYHSHFSAQYGNGVVGTIQINGPASLPYDIDLGVFPITDYYYRAADDLVHFTQNN 240 QYGTSWYHSHFSAQYGNGVVGTIQI+GPASLPYDIDLGVFP+ DYYYR+AD+LVHFTQ+N Sbjct: 172 QYGTSWYHSHFSAQYGNGVVGTIQIDGPASLPYDIDLGVFPLMDYYYRSADELVHFTQSN 231 Query: 241 APPFSDNVLINGTAVNPNTGEGQYANVTLTPGKRHRLRILNTSTENHFQVSLVNHTMTVI 300 P SDNVL NGTA +P TG GQ+ NVTLTPGKRHRLRI+NTST+NHFQVSLV H MTVI Sbjct: 232 GAPPSDNVLFNGTARHPETGAGQWYNVTLTPGKRHRLRIINTSTDNHFQVSLVGHNMTVI 291 Query: 301 AADMVPVNAMTVDSLFLAVGQRYDVVIDASRAPDNYWFNVTFGGQAACGGSLNPHPAAIF 360 A DMVPVNA TV SLFLAVGQRYDV IDA+ NYWFNVTFG CG S N PAAIF Sbjct: 292 ATDMVPVNAFTVSSLFLAVGQRYDVTIDANSPVGNYWFNVTFG-DGLCGSSNNKFPAAIF 350 Query: 361 HYAGAPGGLPTDEGTPPVDHQCLDTLDVRPVVPRSVPVNSFVKRPDNTLPVALDLTGTPL 420 Y GAP LPTD+G P +H CLD L++ PVV RS PVN+FVKRP NTL V LD+ GTPL Sbjct: 351 RYQGAPATLPTDQGLPVPNHMCLDNLNLTPVVTRSAPVNNFVKRPSNTLGVTLDIGGTPL 410 Query: 421 FVWKVNGSDINVDWGKPIIDYILTGNTSYPVSDNIVQVDAVDQWTYWLIENDPEGPF-SL 479 FVWKVNGS INVDWGKPI+DY+++GNTSYPVSDNIVQVDAVDQWTYWLIENDP P SL Sbjct: 411 FVWKVNGSAINVDWGKPILDYVMSGNTSYPVSDNIVQVDAVDQWTYWLIENDPTNPIVSL 470 Query: 480 PHPMHLHGHDFLVLGRSPDVPAASQQRFVFDPAVDLARLNGDNPPRRDTTMLPAGGWLLL 539 PHPMHLHGHDFLVLGRSPD ++ R +FDPA DL RL G+NP RRD TMLPAGGWLLL Sbjct: 471 PHPMHLHGHDFLVLGRSPDELPSAGVRHIFDPAKDLPRLKGNNPVRRDVTMLPAGGWLLL 530 Query: 540 AFRTDNPGAWLFHCHIAWHVSGGLSVDFLERPADLRQRIS----QEDEDDFNRVCDEWRA 595 AF+TDNPGAWLFHCHIAWHVSGGLSVDFLERP DLR +++ + D DDFNRVC EW A Sbjct: 531 AFKTDNPGAWLFHCHIAWHVSGGLSVDFLERPNDLRTQLNSNAKRADRDDFNRVCREWNA 590 Query: 596 YWPTNPYPKIDSGL 609 YWPTNP+PKIDSGL Sbjct: 591 YWPTNPFPKIDSGL 604 >6F5K-A nrPDB Length = 559 Score = 707 bits (1824), Expect = 0.0, Method: Composition-based stats. Identities = 421/559 (75%), Positives = 477/559 (85%) Query: 51 EPTCNTPSNRACWSDGFDINTDYEVSTPDTGVTQSYVFNLTEVDNWMGPDGVVKEKVMLI 110 + +CNTPSNRACW+DG+DINTDYEV +PDTGV + Y LTEVDNW GPDGVVKEKVML+ Sbjct: 1 QQSCNTPSNRACWTDGYDINTDYEVDSPDTGVVRPYTLTLTEVDNWTGPDGVVKEKVMLV 60 Query: 111 NGNIMGPNIVANWGDTVEVTVINNLVTNGTSIHWHGIHQKDTNLHDGANGVTECPIPPKG 170 N +I+GP I A+WGDT++VTVINNL TNGTSIHWHG+HQK TNLHDGANG+TECPIPPKG Sbjct: 61 NNSIIGPTIFADWGDTIQVTVINNLETNGTSIHWHGLHQKGTNLHDGANGITECPIPPKG 120 Query: 171 GQRTYRWRARQYGTSWYHSHFSAQYGNGVVGTIQINGPASLPYDIDLGVFPITDYYYRAA 230 G++ YR++A+QYGTSWYHSHFSAQYGNGVVG IQINGPASLPYD DLGVFPI+DYYY +A Sbjct: 121 GRKVYRFKAQQYGTSWYHSHFSAQYGNGVVGAIQINGPASLPYDTDLGVFPISDYYYSSA 180 Query: 231 DDLVHFTQNNAPPFSDNVLINGTAVNPNTGEGQYANVTLTPGKRHRLRILNTSTENHFQV 290 D+LV T+N+ PFSDNVL NGTA +P TGEG+YANVTLTPG+RHRLR++NTS ENHFQV Sbjct: 181 DELVELTKNSGAPFSDNVLFNGTAKHPETGEGEYANVTLTPGRRHRLRLINTSVENHFQV 240 Query: 291 SLVNHTMTVIAADMVPVNAMTVDSLFLAVGQRYDVVIDASRAPDNYWFNVTFGGQAACGG 350 SLVNHTMT+IAADMVPVNAMTVDSLFL VGQRYDVVI+ASR P NYWFNVTFGG CGG Sbjct: 241 SLVNHTMTIIAADMVPVNAMTVDSLFLGVGQRYDVVIEASRTPGNYWFNVTFGGGLLCGG 300 Query: 351 SLNPHPAAIFHYAGAPGGLPTDEGTPPVDHQCLDTLDVRPVVPRSVPVNSFVKRPDNTLP 410 S NP+PAAIFHYAGAPGG PTDEG PVDH CLD +++PVV R VP++ F KRPDNTL Sbjct: 301 SRNPYPAAIFHYAGAPGGPPTDEGKAPVDHNCLDLPNLKPVVARDVPLSGFAKRPDNTLD 360 Query: 411 VALDLTGTPLFVWKVNGSDINVDWGKPIIDYILTGNTSYPVSDNIVQVDAVDQWTYWLIE 470 V LD TGTPLFVWKVNGS IN+DWG+P++DY+LT NTS+P NIV+V+ DQW+YWLIE Sbjct: 361 VTLDTTGTPLFVWKVNGSAINIDWGRPVVDYVLTQNTSFPPGYNIVEVNGADQWSYWLIE 420 Query: 471 NDPEGPFSLPHPMHLHGHDFLVLGRSPDVPAASQQRFVFDPAVDLARLNGDNPPRRDTTM 530 NDP PF+LPHPMHLHGHDF VLGRSPD AS +R VFDPA D L+G NP RRD TM Sbjct: 421 NDPGAPFTLPHPMHLHGHDFYVLGRSPDESPASNERHVFDPARDAGLLSGANPVRRDVTM 480 Query: 531 LPAGGWLLLAFRTDNPGAWLFHCHIAWHVSGGLSVDFLERPADLRQRISQEDEDDFNRVC 590 LPA GW++LAFR DNPGAWLFHCHIAWHVSGGL V +LER DLR +S D DD +R+C Sbjct: 481 LPAFGWVVLAFRADNPGAWLFHCHIAWHVSGGLGVVYLERADDLRGAVSDADADDLDRLC 540 Query: 591 DEWRAYWPTNPYPKIDSGL 609 +WR YWPTNPYPK DSGL Sbjct: 541 ADWRRYWPTNPYPKSDSGL 559 >3SQR-A nrPDB Length = 580 Score = 559 bits (1440), Expect = e-159, Method: Composition-based stats. Identities = 216/578 (37%), Positives = 320/578 (55%), Gaps = 41/578 (7%) Query: 47 LRPREPT----CNTPSNRACWSDGFDINTDYEVSTPDTGVTQSYVFNLTEVDNWMGPDGV 102 L PR+ T N+ ++R+CW + + I+T++ TP TGVT+ Y ++ ++ + PDG Sbjct: 29 LTPRQNTTASCANSATSRSCWGE-YSIDTNWYDVTP-TGVTREYWLSVE--NSTITPDGY 84 Query: 103 VKEKVMLINGNIMGPNIVANWGDTVEVTVINNLVTNGTSIHWHGIHQKDTNLHDGANGVT 162 + M NG + GP I+A+WGD + + V NNL NGTSIHWHGI Q + +DG GVT Sbjct: 85 TR-SAMTFNGTVPGPAIIADWGDNLIIHVTNNLEHNGTSIHWHGIRQLGSLEYDGVPGVT 143 Query: 163 ECPIPPKGGQRTYRWRARQYGTSWYHSHFSAQYGNGVVGTIQINGPASLPYDIDLGVFPI 222 +CPI P G TY+++ QYGT+WYHSHFS QYG+G+ G + INGPA+ YD D+GV + Sbjct: 144 QCPIAP-GDTLTYKFQVTQYGTTWYHSHFSLQYGDGLFGPLIINGPATADYDEDVGVIFL 202 Query: 223 TDYYYRAADDLVHFTQNNAPPFSDNVLINGTAVNPNT--------GEGQYANVTLTPGKR 274 D+ + + ++ + APP +N L+NGT + G G+ +T G + Sbjct: 203 QDWAHESVFEIWDTARLGAPPALENTLMNGTNTFDCSASTDPNCVGGGKKFELTFVEGTK 262 Query: 275 HRLRILNTSTENHFQVSLVNHTMTVIAADMVPVNAMTVDSLFLAVGQRYDVVIDASRAPD 334 +RLR++N ++HF+ ++ NHT+TVIA D+VP+ T D+L + +GQRYDV+++A+ A D Sbjct: 263 YRLRLINVGIDSHFEFAIDNHTLTVIANDLVPIVPYTTDTLLIGIGQRYDVIVEANAAAD 322 Query: 335 NYWFNVTFGGQAACGGSLNPHPAAIFHYAGAPGGLPTDEGTPPVDHQCLDTLDVRPVVPR 394 NYW +G + + I Y + PT GT P C D V +VP Sbjct: 323 NYWIRGNWGTTCSTNNEA-ANATGILRYDSSSIANPTSVGTTP-RGTCEDEP-VASLVPH 379 Query: 395 SVPVNSFVKRPDNTLPVALDLTGTPLFVWKVNGSDINVDWGKPIIDYILTGNTSYPVSDN 454 D + A T F W +N S + +DW P I T +P N Sbjct: 380 LALDVGGYSLVDEQVSSAF----TNYFTWTINSSSLLLDWSSPTTLKIFNNETIFPTEYN 435 Query: 455 IV---QVDAVDQWTYWLIENDPEGPFSLPHPMHLHGHDFLVLGRSPDVPAASQQRFVFDP 511 +V Q +A ++W ++IE+ F + HP+HLHGHDF ++ + D VF+ Sbjct: 436 VVALEQTNANEEWVVYVIEDLTG--FGIWHPIHLHGHDFFIVAQETD---------VFNS 484 Query: 512 AVDLARLNGDNPPRRDTTMLPAGGWLLLAFRTDNPGAWLFHCHIAWHVSGGLSVDFLERP 571 A+ N NPPRRD LP G+L +AF+ DNPG+WL HCHIAWH S GL++ F+E Sbjct: 485 DESPAKFNLVNPPRRDVAALPGNGYLAIAFKLDNPGSWLLHCHIAWHASEGLAMQFVESQ 544 Query: 572 ADLRQRISQEDEDDFNRVCDEWRAYWPTNPYPKIDSGL 609 + + +++ D F C W AY PT + + DSG+ Sbjct: 545 SSIAVKMT--DTAIFEDTCANWNAYTPTQLFAEDDSGI 580 >2XYB-A nrPDB Length = 497 Score = 550 bits (1417), Expect = e-157, Method: Composition-based stats. Identities = 166/531 (31%), Positives = 239/531 (45%), Gaps = 54/531 (10%) Query: 87 VFNLTEVDNWMGPDGVVKEKVMLINGNIMGPNIVANWGDTVEVTVINNL----VTNGTSI 142 V +LT + + PDG +E V+ +NG P I N GD ++ VI+ L + +SI Sbjct: 5 VADLTLTNAQVSPDGFAREAVV-VNGITPAPLITGNKGDRFQLNVIDQLTNHTMLKTSSI 63 Query: 143 HWHGIHQKDTNLHDGANGVTECPIPPKGGQRTYRWRA-RQYGTSWYHSHFSAQYGNGVVG 201 HWHG Q+ TN DG V +CPI G Y ++ Q GT WYHSH S QY +G+ G Sbjct: 64 HWHGFFQQGTNWADGPAFVNQCPIA-SGHSFLYDFQVPDQAGTFWYHSHLSTQYCDGLRG 122 Query: 202 TIQI---NGPASLPYDID--LGVFPITDYYYRAADDLVHFTQNNAPPFSDNVLINGTAVN 256 + N P + YDID V + D+Y+ AA F P SD+ LING Sbjct: 123 PFVVYDPNDPHASLYDIDNDDTVITLADWYHVAAKLGPRF-----PFGSDSTLINGLGRT 177 Query: 257 PNTGEGQYANVTLTPGKRHRLRILNTSTENHFQVSLVNHTMTVIAADMVPVNAMTVDSLF 316 A + +T GKR+R R+++ S + + S+ NHTMT+I AD + + VDS+ Sbjct: 178 TGIAPSDLAVIKVTQGKRYRFRLVSLSCDPNHTFSIDNHTMTIIEADSINTQPLEVDSIQ 237 Query: 317 LAVGQRYDVVIDASRAPDNYWFNVT--FGGQAACGGSLNPHPAAIFHYAGAPGGLPTDEG 374 + QRY V+DAS+ DNYW FG GG +AI Y GAP PT Sbjct: 238 IFAAQRYSFVLDASQPVDNYWIRANPAFGNTGFAGG----INSAILRYDGAPEIEPTSVQ 293 Query: 375 TPPVDHQCLDTLDVRPVVPRSVPVNSFVKRPDNTLPVALDLTGTPLFVWKVNGSDINVDW 434 T P + L+ +D+ P+ P VP + D L + + GT F+ V Sbjct: 294 TTP--TKPLNEVDLHPLSPMPVPGSPEPGGVDKPLNLVFNFNGTNFFIND----HTFVPP 347 Query: 435 GKPIIDYILTGNTSYPVSDNIVQVDAVDQWTYWLIE---NDPEGPFSLPHPMHLHGHDFL 491 P++ IL+G + D + + + IE PHP HLHGH F Sbjct: 348 SVPVLLQILSGAQA--AQDLVPEGSVFVLPSNSSIEISFPATANAPGFPHPFHLHGHAFA 405 Query: 492 VLGRSPDVPAASQQRFVFDPAVDLARLNGDNPPRRDTTMLP-AGGWLLLAFRTDNPGAWL 550 V+ + + N DNP RD G + + F T+NPG W Sbjct: 406 VVRSAG-----------------SSVYNYDNPIFRDVVSTGQPGDNVTIRFETNNPGPWF 448 Query: 551 FHCHIAWHVSGGLSVDFLERPADLRQRISQEDEDDFNRVCDEWRAYWPTNP 601 HCHI +H+ G +V E D + + ++ +C + A P++ Sbjct: 449 LHCHIDFHLDAGFAVVMAEDTPD--TKAANPVPQAWSDLCPIYDALDPSDL 497 >5NQ7-A nrPDB Length = 518 Score = 546 bits (1407), Expect = e-156, Method: Composition-based stats. Identities = 165/537 (30%), Positives = 239/537 (44%), Gaps = 66/537 (12%) Query: 87 VFNLTEVDNWMGPDGVVKEKVMLINGNIMGPNIVANWGDTVEVTVINNL----VTNGTSI 142 V +LT + + PDG +E V+ +NG P I GD ++ VI+NL + TSI Sbjct: 26 VADLTLTNAAVSPDGFTREAVV-VNGITPAPLIAGKKGDRFQLNVIDNLTNHTMLKTTSI 84 Query: 143 HWHGIHQKDTNLHDGANGVTECPIPPKGGQRTYRWRA-RQYGTSWYHSHFSAQYGNGVVG 201 HWHG Q TN DG + V +CPI G Y ++ Q GT WYHSH S QY +G+ G Sbjct: 85 HWHGFFQHGTNWADGVSFVNQCPIA-SGHSFLYDFQVPDQAGTFWYHSHLSTQYCDGLRG 143 Query: 202 TIQI---NGPASLPYDID--LGVFPITDYYYRAADDLVHFTQNNAPPFSDNVLINGTAVN 256 + N P + YDID V + D+Y+ AA F P +D LING Sbjct: 144 PFVVYDPNDPQASLYDIDNDDTVITLADWYHLAAKVGQRF-----PLGADATLINGLGRT 198 Query: 257 PNTGEGQYANVTLTPGKRHRLRILNTSTENHFQVSLVNHTMTVIAADMVPVNAMTVDSLF 316 P T A + +T GKR+R R+++ S + + S+ HTMT+I AD V + VDS+ Sbjct: 199 PGTTSADLAVIKVTQGKRYRFRLVSLSCDPNHTFSIDGHTMTIIEADSVNTQPLEVDSIQ 258 Query: 317 LAVGQRYDVVIDASRAPDNYWFNVT--FGGQAACGGSLNPHPAAIFHYAGAPGGLPTDEG 374 + QRY V+DAS+ DNYW FG GG +AI Y GAP Sbjct: 259 IFAAQRYSFVLDASQPVDNYWIRANPPFGNVGFAGG----INSAILRYDGAPEVE--PTT 312 Query: 375 TPPVDHQCLDTLDVRPVVPRSVPVNSFVKRPDNTLPVALDLTGTPLFVWKVNGSDINVDW 434 T + L+ D+ P+ P VP D L + + GT F+ + V Sbjct: 313 TQTTPTKPLNEADLHPLTPMPVPGRPEPGGVDKPLNMVFNFNGTNFFIN----NHSFVPP 368 Query: 435 GKPIIDYILTGNTSYPVSDNIVQVDAVDQWTYWLIENDPEGPFSL---------PHPMHL 485 P++ IL+G + D V + + +++ ++ S PHP HL Sbjct: 369 SVPVLLQILSGAQAAQ--------DLVPEGSVYVLPSNASIEISFPATANAPGSPHPFHL 420 Query: 486 HGHDFLVLGRSPDVPAASQQRFVFDPAVDLARLNGDNPPRRDTTMLP-AGGWLLLAFRTD 544 HGH F V+ + + N DNP RD G + + F+T+ Sbjct: 421 HGHTFAVVRSAG-----------------SSEYNYDNPVFRDVVSTGTPGDNVTIRFQTN 463 Query: 545 NPGAWLFHCHIAWHVSGGLSVDFLERPADLRQRISQEDEDDFNRVCDEWRAYWPTNP 601 NPG W HCHI +H+ G +V E D + ++ +C + A P++ Sbjct: 464 NPGPWFLHCHIDFHLDAGFAVVMAEDTPD--TASVNQVPQSWSDLCPIYDALDPSDL 518 >5NQ8-A nrPDB Length = 518 Score = 545 bits (1405), Expect = e-155, Method: Composition-based stats. Identities = 167/537 (31%), Positives = 240/537 (44%), Gaps = 66/537 (12%) Query: 87 VFNLTEVDNWMGPDGVVKEKVMLINGNIMGPNIVANWGDTVEVTVINNL----VTNGTSI 142 V +LT + + PDG +E V+ +NG P I GD ++ VI+NL + TSI Sbjct: 26 VADLTLTNAAVSPDGFSREAVV-VNGVTPAPLISGQKGDRFQLNVIDNLTNHTMLKTTSI 84 Query: 143 HWHGIHQKDTNLHDGANGVTECPIPPKGGQRTYRWRA-RQYGTSWYHSHFSAQYGNGVVG 201 HWHG Q TN DG V +CPI G Y ++ Q GT WYHSH S QY +G+ G Sbjct: 85 HWHGFFQHGTNWADGPAFVNQCPIA-SGHSFLYDFQVPDQAGTFWYHSHLSTQYCDGLRG 143 Query: 202 TIQI---NGPASLPYDID--LGVFPITDYYYRAADDLVHFTQNNAPPFSDNVLINGTAVN 256 + N P + YDID V + D+Y+ AA F PP SD LING + Sbjct: 144 PFVVYDPNDPQASLYDIDNDDTVITLADWYHVAAKLGPRF-----PPGSDATLINGLGRS 198 Query: 257 PNTGEGQYANVTLTPGKRHRLRILNTSTENHFQVSLVNHTMTVIAADMVPVNAMTVDSLF 316 P T A + +T GKR+R R+++ S + + S+ HTMT+I AD V + VDS+ Sbjct: 199 PGTTAADLAVIKVTQGKRYRFRLVSLSCDPNHTFSIDGHTMTIIEADSVNTQPLEVDSIQ 258 Query: 317 LAVGQRYDVVIDASRAPDNYWFNVT--FGGQAACGGSLNPHPAAIFHYAGAPGGLPTDEG 374 + QRY V+DAS+ DNYW FG GG +AI Y GAP Sbjct: 259 IFAAQRYSFVLDASQPVDNYWIRANPSFGNTGFAGG----INSAILRYLGAPEIE--PTT 312 Query: 375 TPPVDHQCLDTLDVRPVVPRSVPVNSFVKRPDNTLPVALDLTGTPLFVWKVNGSDINVDW 434 T + L +D+ P+ P +VP D L + + GT F+ + V Sbjct: 313 TQTTPTKPLTEVDLHPLTPMAVPGRPEPGGVDKPLNMVFNFNGTNFFIN----NHSFVPP 368 Query: 435 GKPIIDYILTGNTSYPVSDNIVQVDAVDQWTYWLIENDPEGPFSL---------PHPMHL 485 P++ IL+G + D V + + +++ ++ S PHP HL Sbjct: 369 SVPVLLQILSGAQAAQ--------DLVPEGSVYVLPSNSSIEISFPATVNAPGAPHPFHL 420 Query: 486 HGHDFLVLGRSPDVPAASQQRFVFDPAVDLARLNGDNPPRRDTTMLP-AGGWLLLAFRTD 544 HGH F V+ + + N DNP RD G + + F+T Sbjct: 421 HGHTFAVVRSAG-----------------SSEYNYDNPIFRDVVSTGTPGDNVTIRFQTA 463 Query: 545 NPGAWLFHCHIAWHVSGGLSVDFLERPADLRQRISQEDEDDFNRVCDEWRAYWPTNP 601 NPG W HCHI +H+ G +V E D + ++ +C + A P++ Sbjct: 464 NPGPWFLHCHIDFHLDAGFAVVMAEDTPD--TTAANPVPQAWSDLCPIYDALDPSDL 518 >3X1B-A nrPDB Length = 521 Score = 543 bits (1399), Expect = e-155, Method: Composition-based stats. Identities = 163/525 (31%), Positives = 230/525 (43%), Gaps = 51/525 (9%) Query: 87 VFNLTEVDNWMGPDGVVKEKVMLINGNIMGPNIVANWGDTVEVTVINNL----VTNGTSI 142 V NL + + PDG ++ V+ +NG GP IV N GD + VI+ L + TSI Sbjct: 26 VANLKIGNAAVSPDGYTRDAVV-VNGATPGPLIVGNKGDNFRLNVIDELTNHTMLKSTSI 84 Query: 143 HWHGIHQKDTNLHDGANGVTECPIPPKGGQRTYRWRA-RQYGTSWYHSHFSAQYGNGVVG 201 HWHG Q TN DG V +CPI G +Y ++A Q GT WYHSH S QY +G+ G Sbjct: 85 HWHGFFQHGTNWADGGAFVNQCPIS-SGHSFSYNFQAKDQAGTFWYHSHLSTQYCDGLRG 143 Query: 202 TIQI---NGPASLPYDIDL--GVFPITDYYYRAADDLVHFTQNNAPPFSDNVLINGTAVN 256 + P YD+D V + D+Y+ AA F P SD+ LING + Sbjct: 144 PFVVYDPKDPHKKLYDVDNESTVITLEDWYHTAARLGPRF-----PLGSDSTLINGLGRS 198 Query: 257 PNTGEGQYANVTLTPGKRHRLRILNTSTENHFQVSLVNHTMTVIAADMVPVNAMTVDSLF 316 T G A + +T GKR+R R+++ S + + S+ H MT+I AD V TVDSL Sbjct: 199 ATTATGDLAVIKVTRGKRYRFRLVSLSCDPFYTFSIDGHNMTIIEADAVNTKPHTVDSLE 258 Query: 317 LAVGQRYDVVIDASRAPDNYWFNVTFGGQAACGGSLNPHPAAIFHYAGAPGGLPTDEGTP 376 + GQRY +++A++ DNYW G N +AI Y GA P P Sbjct: 259 IFAGQRYSFILNANQPVDNYWVRAN--PNFGNVGFTNGINSAILRYDGAAVAEPAT-AIP 315 Query: 377 PVDHQCLDTLDVRPVVPRSVPVNSFVKRPDNTLPVALDLTGTPLFVWKVNGSDINVDWGK 436 P L D+ P+V VP + D L + GT F+ + +V Sbjct: 316 PASVTPLLETDLHPLVSTPVPGSPVAGGVDKALNFVFNFDGTNFFINDATFTPPSV---- 371 Query: 437 PIIDYILTGNTSYPVSDNIVQVDAVDQWTYWLIE---NDPEGPFSLPHPMHLHGHDFLVL 493 P++ IL+G + D + + IE +PHP HLHGH F V+ Sbjct: 372 PVLLQILSGAQA--AQDLLPSGSVIPLPALSTIELSFPATANAPGVPHPFHLHGHTFAVV 429 Query: 494 GRSPDVPAASQQRFVFDPAVDLARLNGDNPPRRDTTMLP---AGGWLLLAFRTDNPGAWL 550 + N ++P RD AG + + F TDNPG W Sbjct: 430 RSAGST-----------------AYNYEDPVWRDVVSTGTPAAGDNVTIRFVTDNPGPWF 472 Query: 551 FHCHIAWHVSGGLSVDFLERPADLRQRISQEDEDDFNRVCDEWRA 595 HCHI +H+ G +V F E + ++ +C + A Sbjct: 473 LHCHIDFHLEAGFAVVFAEDLPG--TPAANPVPQSWSDLCPIYDA 515 >3V9C-A nrPDB Length = 499 Score = 542 bits (1396), Expect = e-154, Method: Composition-based stats. Identities = 166/538 (30%), Positives = 247/538 (45%), Gaps = 68/538 (12%) Query: 87 VFNLTEVDNWMGPDGVVKEKVMLINGNIMGPNIVANWGDTVEVTVINNL----VTNGTSI 142 V +LT D + PDG ++ V+ +NG GP + N GD ++ VI+NL + TSI Sbjct: 5 VADLTITDAAVSPDGFSRQAVV-VNGVTPGPLVAGNIGDRFQLNVIDNLTNHTMLKSTSI 63 Query: 143 HWHGIHQKDTNLHDGANGVTECPIPPKGGQRTYRWRA-RQYGTSWYHSHFSAQYGNGVVG 201 HWHG Q TN DG + +CPI P G Y ++ Q GT WYHSH S QY +G+ G Sbjct: 64 HWHGFFQHGTNWADGPAFINQCPISP-GHSFLYDFQVPDQAGTFWYHSHLSTQYCDGLRG 122 Query: 202 TIQI---NGPASLPYDID--LGVFPITDYYYRAADDLVHFTQNNAPPFSDNVLINGTAVN 256 + N P + YD+D V + D+Y+ AA F P +D LING Sbjct: 123 PFVVYDPNDPHASRYDVDNDDTVITLADWYHTAAKLGPRF-----PGGADATLINGKGRA 177 Query: 257 PNTGEGQYANVTLTPGKRHRLRILNTSTENHFQVSLVNHTMTVIAADMVPVNAMTVDSLF 316 P+ + + + +T GKR+R R+++ S + S+ H +T+I D V + VDS+ Sbjct: 178 PSDSVAELSVIKVTKGKRYRFRLVSLSCNPNHTFSIDGHNLTIIEVDSVNSQPLEVDSIQ 237 Query: 317 LAVGQRYDVVIDASRAPDNYWF--NVTFGGQAACGGSLNPHPAAIFHYAGAPGGLPTDEG 374 + QRY V+DA++A DNYW N FG GG +AI Y GAP PT Sbjct: 238 IFAAQRYSFVLDANQAVDNYWIRANPNFGNVGFDGG----INSAILRYDGAPAVEPTTNQ 293 Query: 375 TPPVDHQCLDTLDVRPVVPRSVPVNSFVKRPDNTLPVALDLTGTPLFVWKVNGSDINVDW 434 T V + L+ +D+ P+V VP + D + +A + G+ F +NG+ V Sbjct: 294 TTSV--KPLNEVDLHPLVSTPVPGSPSSGGVDKAINMAFNFNGSNFF---INGASF-VPP 347 Query: 435 GKPIIDYILTGNTSYPVSDNIVQVDAVDQWTYWLIENDPEGPFSL---------PHPMHL 485 P++ IL+G D + + +++ ++ S PHP HL Sbjct: 348 TVPVLLQILSGAQ--------TAQDLLPSGSVYVLPSNASIEISFPATAAAPGAPHPFHL 399 Query: 486 HGHDFLVLGRSPDVPAASQQRFVFDPAVDLARLNGDNPPRRDTTMLP---AGGWLLLAFR 542 HGH F V+ + N DNP RD AG + + F Sbjct: 400 HGHTFAVVRSAG-----------------STVYNYDNPIFRDVVSTGTPAAGDNVTIRFD 442 Query: 543 TDNPGAWLFHCHIAWHVSGGLSVDFLERPADLRQRISQEDEDDFNRVCDEWRAYWPTN 600 T+NPG W HCHI +H+ GG +V E D++ ++ +C + A P + Sbjct: 443 TNNPGPWFLHCHIDFHLEGGFAVVMAEDTPDVK--AVNPVPQAWSDLCPTYDALDPND 498 >1KYA-A nrPDB Length = 499 Score = 540 bits (1391), Expect = e-154, Method: Composition-based stats. Identities = 165/538 (30%), Positives = 252/538 (46%), Gaps = 68/538 (12%) Query: 87 VFNLTEVDNWMGPDGVVKEKVMLINGNIMGPNIVANWGDTVEVTVINNL----VTNGTSI 142 V +LT + + PDG ++ V+ +NG GP I N GD ++ VI+NL + TSI Sbjct: 5 VADLTITNAAVSPDGFSRQAVV-VNGGTPGPLITGNMGDRFQLNVIDNLTNHTMLKSTSI 63 Query: 143 HWHGIHQKDTNLHDGANGVTECPIPPKGGQRTYRWRA-RQYGTSWYHSHFSAQYGNGVVG 201 HWHG QK TN DG + +CPI G Y ++ Q GT WYHSH S QY +G+ G Sbjct: 64 HWHGFFQKGTNWADGPAFINQCPIS-SGHSFLYDFQVPDQAGTFWYHSHLSTQYCDGLRG 122 Query: 202 TIQI---NGPASLPYDID--LGVFPITDYYYRAADDLVHFTQNNAPPFSDNVLINGTAVN 256 + N PA+ YD+D V + D+Y+ AA F P +D LING + Sbjct: 123 PFVVYDPNDPAADLYDVDNDDTVITLVDWYHVAAKLGPAF-----PLGADATLINGKGRS 177 Query: 257 PNTGEGQYANVTLTPGKRHRLRILNTSTENHFQVSLVNHTMTVIAADMVPVNAMTVDSLF 316 P+T + +++TPGKR+R R+++ S + ++ S+ H MT+I D + + VDS+ Sbjct: 178 PSTTTADLSVISVTPGKRYRFRLVSLSCDPNYTFSIDGHNMTIIETDSINTAPLVVDSIQ 237 Query: 317 LAVGQRYDVVIDASRAPDNYWF--NVTFGGQAACGGSLNPHPAAIFHYAGAPGGLPTDEG 374 + QRY V++A++A DNYW N FG GG +AI Y GA P Sbjct: 238 IFAAQRYSFVLEANQAVDNYWIRANPNFGNVGFTGG----INSAILRYDGAAAVEP--TT 291 Query: 375 TPPVDHQCLDTLDVRPVVPRSVPVNSFVKRPDNTLPVALDLTGTPLFVWKVNGSDINVDW 434 T L+ +++ P+V +VP + D + +A + GT F +NG+ Sbjct: 292 TQTTSTAPLNEVNLHPLVATAVPGSPVAGGVDLAINMAFNFNGTNFF---INGASFT-PP 347 Query: 435 GKPIIDYILTGNTSYPVSDNIVQVDAVDQWTYWLIENDPEGPFSL---------PHPMHL 485 P++ I++G + D + + + + ++ + S PHP HL Sbjct: 348 TVPVLLQIISGAQNAQ--------DLLPSGSVYSLPSNADIEISFPATAAAPGAPHPFHL 399 Query: 486 HGHDFLVLGRSPDVPAASQQRFVFDPAVDLARLNGDNPPRRDTTMLP---AGGWLLLAFR 542 HGH F V+ + N DNP RD AG + + FR Sbjct: 400 HGHAFAVVRSAGST-----------------VYNYDNPIFRDVVSTGTPAAGDNVTIRFR 442 Query: 543 TDNPGAWLFHCHIAWHVSGGLSVDFLERPADLRQRISQEDEDDFNRVCDEWRAYWPTN 600 TDNPG W HCHI +H+ G +V F E D+ + ++ +C + A P++ Sbjct: 443 TDNPGPWFLHCHIDFHLEAGFAVVFAEDIPDVAS--ANPVPQAWSDLCPTYDARDPSD 498 >4A2F-A nrPDB Length = 497 Score = 537 bits (1384), Expect = e-153, Method: Composition-based stats. Identities = 161/528 (30%), Positives = 230/528 (43%), Gaps = 55/528 (10%) Query: 87 VFNLTEVDNWMGPDGVVKEKVMLINGNIMGPNIVANWGDTVEVTVINNL----VTNGTSI 142 V +LT + + PDG ++ + L+N P I N GD ++ VI+N+ + TSI Sbjct: 5 VADLTISNGAVSPDGFSRQAI-LVNDVFPSPLITGNKGDRFQLNVIDNMTNHTMLKSTSI 63 Query: 143 HWHGIHQKDTNLHDGANGVTECPIPPKGGQRTYRWRA-RQYGTSWYHSHFSAQYGNGVVG 201 HWHG Q TN DG V +CPI G Y ++ Q GT WYHSH S QY +G+ G Sbjct: 64 HWHGFFQHGTNWADGPAFVNQCPIS-TGHAFLYDFQVPDQAGTFWYHSHLSTQYCDGLRG 122 Query: 202 TIQI---NGPASLPYDIDL--GVFPITDYYYRAADDLVHFTQNNAPPFSDNVLINGTAVN 256 I + N P + YD+D V + D+Y+ AA P +D LING + Sbjct: 123 PIVVYDPNDPHASLYDVDDDSTVITLADWYHLAAKVGAPV------PTADATLINGLGRS 176 Query: 257 PNTGEGQYANVTLTPGKRHRLRILNTSTENHFQVSLVNHTMTVIAADMVPVNAMTVDSLF 316 T A +T+T GKR+R R+++ S + ++ S+ H++TVI AD V + TVDSL Sbjct: 177 AATLAADLAVITVTKGKRYRFRLVSLSCDPNYTFSIDGHSLTVIEADSVNLKPHTVDSLQ 236 Query: 317 LAVGQRYDVVIDASRAPDNYWFN--VTFGGQAACGGSLNPHPAAIFHYAGAPGGLPTDEG 374 + QRY V++A + DNYW G Q GG +AI Y GA PT Sbjct: 237 IFAAQRYSFVLNADQDVDNYWIRALPNSGTQNFAGG----TNSAILRYDGAAPVEPTTSQ 292 Query: 375 TPPVDHQCLDTLDVRPVVPRSVPVNSFVKRPDNTLPVALDLTGTPLFVWKVNGSDINVDW 434 TP L + + + P + D L +A G +NG+ Sbjct: 293 TP--STNPLVESALTTLKGTAAPGSPTPGGVDLALNMAFGFAGGNF---TINGASFT-PP 346 Query: 435 GKPIIDYILTGNTSYPVSDNIVQVDAVDQWTYWLIE---NDPEGPFSLPHPMHLHGHDFL 491 P++ IL+G S +D + IE PHP HLHGH F Sbjct: 347 TVPVLLQILSGAQS--AADLLPAGSVYSLPANADIEISLPATAAAPGFPHPFHLHGHVFA 404 Query: 492 VLGRSPDVPAASQQRFVFDPAVDLARLNGDNPPRRDTTMLP-AGGWLLLAFRTDNPGAWL 550 V+ + + N NP RD G + + FRTDNPG W Sbjct: 405 VVRSAG-----------------SSTYNYANPVYRDVVSTGAPGDNVTIRFRTDNPGPWF 447 Query: 551 FHCHIAWHVSGGLSVDFLERPADLRQRISQEDEDDFNRVCDEWRAYWP 598 HCHI +H+ G +V E D+ + ++ +C + A P Sbjct: 448 LHCHIDFHLEAGFAVVMAEDIPDV--AATNPVPQAWSDLCPTYDALSP 493 >5MIA-A nrPDB Length = 546 Score = 536 bits (1381), Expect = e-152, Method: Composition-based stats. Identities = 158/523 (30%), Positives = 232/523 (44%), Gaps = 51/523 (9%) Query: 87 VFNLTEVDNWMGPDGVVKEKVMLINGNIMGPNIVANWGDTVEVTVINNL----VTNGTSI 142 V +L + + PDG + V L G GP I N GD ++TV N+L + TSI Sbjct: 25 VTDLHITNANISPDGFSRPAV-LAGGTFPGPTIAGNTGDNFQITVFNDLTDPSMLTDTSI 83 Query: 143 HWHGIHQKDTNLHDGANGVTECPIPPKGGQRTYRWRAR-QYGTSWYHSHFSAQYGNGVVG 201 HWHG+ QK TN DG VT+CPI G Y + Q GT WYHSH S QY +G+ G Sbjct: 84 HWHGLFQKGTNWADGPAFVTQCPII-TGQSFDYNFNVPGQAGTFWYHSHLSTQYCDGLRG 142 Query: 202 TIQI---NGPASLPYDIDL--GVFPITDYYYRAADDLVHFTQNNAPPFSDNVLINGTAVN 256 + N P + YD+D + + D+Y+ A A +D LING + Sbjct: 143 PFVVYDPNDPNASLYDVDDDTTIITLADWYHTLAQQEP----IGAAITADATLINGLGRS 198 Query: 257 -PNTGEGQYANVTLTPGKRHRLRILNTSTENHFQVSLVNHTMTVIAADMVPVNAMTVDSL 315 NT + +T+ GKR+R+R+++ S + ++ S+ H MT+I D V +TVD + Sbjct: 199 FTNTTASPLSVITVQSGKRYRMRLVSISCDPNYLFSIDGHDMTIIEVDGVNSQQLTVDQI 258 Query: 316 FLAVGQRYDVVIDASRAPDNYWFN--VTFGGQAACGGSLNPHPAAIFHYAGAPGGLPTDE 373 + QRY V++A++ NYW GGQ GG +AI Y GA PT Sbjct: 259 QIFAAQRYSFVLNANQPVGNYWIRAQPNSGGQGFDGG----INSAILRYEGATVEDPTTT 314 Query: 374 GTPPVDHQCLDTLDVRPVVPRSVPVNSFVKRPDNTLPVALDLTGTPLFVWKVNGSDINVD 433 + L D+ P+ VP F D+ L + L + V+ V Sbjct: 315 APTTFSN-PLVETDLHPLADLGVPGQPFRGGADDPLVLNLAFANGRFSIDGVSF----VP 369 Query: 434 WGKPIIDYILTGNTSYPVSDNIVQVDAVDQWTYWLIEND-PEGPFSLPHPMHLHGHDFLV 492 P++ IL+G + D + + + +IE P G PHP HLHGH+F V Sbjct: 370 PTVPVLLQILSGAQN--AQDLLPAGSVISLPSNSVIEVALPAGAAGGPHPFHLHGHNFAV 427 Query: 493 LGRSPDVPAASQQRFVFDPAVDLARLNGDNPPRRDTTMLPA-GGWLLLAFRTDNPGAWLF 551 + + + N NP RDT + G + + F T+NPG W Sbjct: 428 VQSANNATP-----------------NYVNPIWRDTVSIGGTGDNVTIRFTTNNPGPWFL 470 Query: 552 HCHIAWHVSGGLSVDFLERPADLRQRISQEDEDDFNRVCDEWR 594 HCHI WH+ G ++ F E D + ++ +C + Sbjct: 471 HCHIDWHLEAGFAIVFAEDIPD--TASANPVPQAWSDLCPAYD 511 >1GYC-A nrPDB Length = 499 Score = 536 bits (1381), Expect = e-152, Method: Composition-based stats. Identities = 153/531 (28%), Positives = 233/531 (43%), Gaps = 56/531 (10%) Query: 88 FNLTEVDNWMGPDGVVKEKVMLINGNIMGPNIVANWGDTVEVTVINNL----VTNGTSIH 143 +L + + PDG +++ ++ +NG P I GD ++ V++ L + TSIH Sbjct: 6 ASLVVANAPVSPDGFLRDAIV-VNGVFPSPLITGKKGDRFQLNVVDTLTNHTMLKSTSIH 64 Query: 144 WHGIHQKDTNLHDGANGVTECPIPPKGGQRTYRWRA-RQYGTSWYHSHFSAQYGNGVVGT 202 WHG Q TN DG V +CPI G Y + Q GT WYHSH S QY +G+ G Sbjct: 65 WHGFFQAGTNWADGPAFVNQCPIA-SGHSFLYDFHVPDQAGTFWYHSHLSTQYCDGLRGP 123 Query: 203 IQI---NGPASLPYDIDL--GVFPITDYYYRAADDLVHFTQNNAPPFSDNVLINGTAVNP 257 + P + YD+D V +TD+Y+ AA F P +D LING + Sbjct: 124 FVVYDPKDPHASRYDVDNESTVITLTDWYHTAARLGPRF-----PLGADATLINGLGRSA 178 Query: 258 NTGEGQYANVTLTPGKRHRLRILNTSTENHFQVSLVNHTMTVIAADMVPVNAMTVDSLFL 317 +T A + + GKR+R R+++ S + ++ S+ H +TVI D + + VDS+ + Sbjct: 179 STPTAALAVINVQHGKRYRFRLVSISCDPNYTFSIDGHNLTVIEVDGINSQPLLVDSIQI 238 Query: 318 AVGQRYDVVIDASRAPDNYWF--NVTFGGQAACGGSLNPHPAAIFHYAGAPGGLPTDEGT 375 QRY V++A++ NYW N FG GG +AI Y GAP PT T Sbjct: 239 FAAQRYSFVLNANQTVGNYWIRANPNFGTVGFAGG----INSAILRYQGAPVAEPTTTQT 294 Query: 376 PPVDHQCLDTLDVRPVVPRSVPVNSFVKRPDNTLPVALDLTGTPLFVWKVNGSDINVDWG 435 V L ++ P+ VP + D L +A + GT F+ + + V Sbjct: 295 TSV--IPLIETNLHPLARMPVPGSPTPGGVDKALNLAFNFNGTNFFINNASFTPPTV--- 349 Query: 436 KPIIDYILTGNTSYPVSDNIVQVDAVDQWTYWLIE---NDPEGPFSLPHPMHLHGHDFLV 492 P++ IL+G + D + + IE PHP HLHGH F V Sbjct: 350 -PVLLQILSGAQT--AQDLLPAGSVYPLPAHSTIEITLPATALAPGAPHPFHLHGHAFAV 406 Query: 493 LGRSPDVPAASQQRFVFDPAVDLARLNGDNPPRRDTTMLP---AGGWLLLAFRTDNPGAW 549 + + N ++P RD AG + + F+TDNPG W Sbjct: 407 VRSAG-----------------STTYNYNDPIFRDVVSTGTPAAGDNVTIRFQTDNPGPW 449 Query: 550 LFHCHIAWHVSGGLSVDFLERPADLRQRISQEDEDDFNRVCDEWRAYWPTN 600 HCHI +H+ G ++ F E AD++ + ++ +C + N Sbjct: 450 FLHCHIDFHLEAGFAIVFAEDVADVK--AANPVPKAWSDLCPIYDGLSEAN 498 >2QT6-A nrPDB Length = 498 Score = 532 bits (1371), Expect = e-151, Method: Composition-based stats. Identities = 157/532 (29%), Positives = 234/532 (43%), Gaps = 57/532 (10%) Query: 87 VFNLTEVDNWMGPDGVVKEKVMLINGNIMGPNIVANWGDTVEVTVINNL----VTNGTSI 142 V +LT + + PDG + +++N P I N GD ++ ++N + + TSI Sbjct: 5 VADLTVTNANIVPDGF-ERAAIVVNNVFPAPLITGNMGDNFQLNLVNQMTNHTMLKTTSI 63 Query: 143 HWHGIHQKDTNLHDGANGVTECPIPPKGGQRTYRWRAR-QYGTSWYHSHFSAQYGNGVVG 201 HWHG QK TN DG + +CPI G Y ++ Q GT WYHSH S QY +G+ G Sbjct: 64 HWHGFFQKGTNWADGPAFINQCPIA-SGNSFLYDFQVPGQAGTFWYHSHLSTQYCDGLRG 122 Query: 202 TIQI---NGPASLPYDIDL--GVFPITDYYYRAADDLVHFTQNNAPPFSDNVLINGTAVN 256 + N P + YD+D V + D+Y+ AA F P +D+ LING + Sbjct: 123 PFVVYDPNDPHANLYDVDDESTVITLADWYHVAAKLGPRF-----PKGADSTLINGLGRS 177 Query: 257 PNTGEGQYANVTLTPGKRHRLRILNTSTENHFQVSLVNHTMTVIAADMVPVNAMTVDSLF 316 +T A +++T GKR+R R+++ S + ++ S+ +H +TVI AD V +TVDS+ Sbjct: 178 TSTPTADLAVISVTKGKRYRFRLVSLSCDPNYTFSIDSHQLTVIEADGVSTQPVTVDSIQ 237 Query: 317 LAVGQRYDVVIDASRAPDNYWF--NVTFGGQAACGGSLNPHPAAIFHYAGAPGGLPTDEG 374 + QRY V++A++ DNYW N FG G +AI Y A P Sbjct: 238 IFAAQRYSFVLNANQDVDNYWIRANPNFGTTGFADG----VNSAILRYDDADPVEPVTNQ 293 Query: 375 TPPVDHQCLDTLDVRPVVPRSVPVNSFVKRPDNTLPVALDLTGTPLFVWKVNGSDINVDW 434 T L D+ P+ VP N D L +A + GT F +NG Sbjct: 294 T---GTTLLLETDLHPLTSMPVPGNPTQGGADLNLNMAFNFDGTNFF---INGESFT-PP 346 Query: 435 GKPIIDYILTGNTSYPVSDNIVQVDAVDQWTYWLIE---NDPEGPFSLPHPMHLHGHDFL 491 P++ I++G D + + IE PHP HLHGH F Sbjct: 347 TVPVLLQIISGA--NTAQDLLPSGSVYSLPSNSSIEITFPATTAAPGAPHPFHLHGHVFA 404 Query: 492 VLGRSPDVPAASQQRFVFDPAVDLARLNGDNPPRRDTTMLP---AGGWLLLAFRTDNPGA 548 V+ + N D+P RD AG + + F+TDNPG Sbjct: 405 VVRSAG-----------------STSYNYDDPVWRDVVSTGTPQAGDNVTIRFQTDNPGP 447 Query: 549 WLFHCHIAWHVSGGLSVDFLERPADLRQRISQEDEDDFNRVCDEWRAYWPTN 600 W HCHI +H+ G +V E + + ++ +C + A P+N Sbjct: 448 WFLHCHIDFHLDAGFAVVMAEDIPN--TVNANPVPQAWSNLCPTYDALEPSN 497 >4JHU-A nrPDB Length = 496 Score = 531 bits (1367), Expect = e-151, Method: Composition-based stats. Identities = 159/530 (30%), Positives = 228/530 (43%), Gaps = 55/530 (10%) Query: 87 VFNLTEVDNWMGPDGVVKEKVMLINGNIMGPNIVANWGDTVEVTVINNL----VTNGTSI 142 V +LT D + PDG ++ + L+N P I N GD ++ VI+N+ + TSI Sbjct: 5 VTDLTISDGPVSPDGFTRQAI-LVNNQFPSPLITGNKGDRFQLNVIDNMNNHTMLKSTSI 63 Query: 143 HWHGIHQKDTNLHDGANGVTECPIPPKGGQRTYRWRA-RQYGTSWYHSHFSAQYGNGVVG 201 HWHG Q TN DG V +CPI P G Y ++ Q GT WYHSH S QY +G+ G Sbjct: 64 HWHGFFQHGTNWADGPAFVNQCPISP-GHSFLYDFQVPDQAGTFWYHSHLSTQYCDGLRG 122 Query: 202 TIQINGPASL---PYDIDL--GVFPITDYYYRAADDLVHFTQNNAPPFSDNVLINGTAVN 256 I + P YD+D V + D+Y+ AA A P +D LING + Sbjct: 123 PIVVYDPQDPHKDLYDVDDDSTVITLADWYHLAAKVGP------AVPTADATLINGLGRS 176 Query: 257 PNTGEGQYANVTLTPGKRHRLRILNTSTENHFQVSLVNHTMTVIAADMVPVNAMTVDSLF 316 +T A +++T GKR+R R+++ S + + S+ HTMTVI AD V + VDS+ Sbjct: 177 ISTLNADLAVISVTKGKRYRFRLVSLSCDPNHTFSIDGHTMTVIEADSVNLKPQVVDSIQ 236 Query: 317 LAVGQRYDVVIDASRAPDNYWFN--VTFGGQAACGGSLNPHPAAIFHYAGAPGGLPTDEG 374 + QRY V++A + NYW G + GG +AI Y GA PT Sbjct: 237 IFAAQRYSFVLNADQDIGNYWIRAMPNSGTRNFDGG----VNSAILRYDGADPVEPTTTQ 292 Query: 375 TPPVDHQCLDTLDVRPVVPRSVPVNSFVKRPDNTLPVALDLTGTPLFVWKVNGSDINVDW 434 TP Q L + + + P + D + +A G +NG+ Sbjct: 293 TP--SSQPLVESALTTLEGTAAPGSPTAGGVDLAINMAFGFAGGRF---TINGASFT-PP 346 Query: 435 GKPIIDYILTGNTSYPVSDNIVQVDAVDQWTYWLIE---NDPEGPFSLPHPMHLHGHDFL 491 P++ IL+G + D + IE PHP HLHGH F Sbjct: 347 TVPVLLQILSGAQN--AQDLLPTGSVYSLPANADIEISLPATAAAPGFPHPFHLHGHTFA 404 Query: 492 VLGRSPDVPAASQQRFVFDPAVDLARLNGDNPPRRDTTMLP-AGGWLLLAFRTDNPGAWL 550 V+ + + N NP RD G + + FRTDNPG W Sbjct: 405 VVRSAG-----------------SSTYNYANPVYRDVVSTGSPGDNVTIRFRTDNPGPWF 447 Query: 551 FHCHIAWHVSGGLSVDFLERPADLRQRISQEDEDDFNRVCDEWRAYWPTN 600 HCHI +H+ G +V E D+ ++ +C + A P + Sbjct: 448 LHCHIDFHLEAGFAVVMAEDIPDV--AAVNPVPQAWSDLCPTYNALDPND 495 >2H5U-A nrPDB Length = 499 Score = 525 bits (1351), Expect = e-149, Method: Composition-based stats. Identities = 158/538 (29%), Positives = 243/538 (45%), Gaps = 68/538 (12%) Query: 87 VFNLTEVDNWMGPDGVVKEKVMLINGNIMGPNIVANWGDTVEVTVINNL----VTNGTSI 142 V + T + PDG ++ V+ +NG GP + N GD ++ VI+NL + TS+ Sbjct: 5 VADNTITNAATSPDGFSRQAVV-VNGVTPGPLVAGNIGDRFQLNVIDNLTNHTMLKTTSV 63 Query: 143 HWHGIHQKDTNLHDGANGVTECPIPPKGGQRTYRWRAR-QYGTSWYHSHFSAQYGNGVVG 201 HWHG Q+ TN DG + +CPI P G Y ++ Q GT WYHSH S QY +G+ G Sbjct: 64 HWHGFFQQGTNWADGPAFINQCPISP-GHSFLYDFQVPNQAGTFWYHSHLSTQYCDGLRG 122 Query: 202 TIQI---NGPASLPYDIDLGV--FPITDYYYRAADDLVHFTQNNAPPFSDNVLINGTAVN 256 + N P + YD+D + D+Y+ AA F P +D+ LING Sbjct: 123 PFVVYDPNDPHASRYDVDNDDTTITLADWYHTAAKLGPAF-----PNGADSTLINGKGRA 177 Query: 257 PNTGEGQYANVTLTPGKRHRLRILNTSTENHFQVSLVNHTMTVIAADMVPVNAMTVDSLF 316 P+ Q + V++T GKR+R R+++ S + +F S+ H T+I D V + DS+ Sbjct: 178 PSDSSAQLSVVSVTKGKRYRFRLVSLSCDPNFTFSIDGHNNTIIETDSVNSQPLNTDSIQ 237 Query: 317 LAVGQRYDVVIDASRAPDNYWF--NVTFGGQAACGGSLNPHPAAIFHYAGAPGGLPTDEG 374 + QRY ++A++A DNYW N FG GG +AI Y GAP PT Sbjct: 238 IFAAQRYSFTLNANQAVDNYWIRANPNFGNVGFNGG----INSAILRYDGAPAVEPTTNQ 293 Query: 375 TPPVDHQCLDTLDVRPVVPRSVPVNSFVKRPDNTLPVALDLTGTPLFVWKVNGSDINVDW 434 + Q L+ ++ P+V VP + D + +A + G+ F +NG+ Sbjct: 294 ST--STQPLNETNLHPLVSTPVPGSPAAGGVDKAINMAFNFNGSNFF---INGASFT-PP 347 Query: 435 GKPIIDYILTGNTSYPVSDNIVQVDAVDQWTYWLIENDPEGPFSL---------PHPMHL 485 P++ IL+G D + + + + ++ S PHP HL Sbjct: 348 SVPVLLQILSGAQ--------TAQDLLPSGSVYTLPSNASIEISFPATAAAPGAPHPFHL 399 Query: 486 HGHDFLVLGRSPDVPAASQQRFVFDPAVDLARLNGDNPPRRDTTMLP---AGGWLLLAFR 542 HGH F V+ + N NP RD AG + + F Sbjct: 400 HGHVFAVVRSAG-----------------STVYNYSNPIFRDVVSTGTPAAGDNVTIRFL 442 Query: 543 TDNPGAWLFHCHIAWHVSGGLSVDFLERPADLRQRISQEDEDDFNRVCDEWRAYWPTN 600 T+NPG W HCHI +H+ GG +V E D++ + ++ +C + A P++ Sbjct: 443 TNNPGPWFLHCHIDFHLEGGFAVVQAEDVPDVK--ATNPVPQAWSDLCPTYDANAPSD 498 >3KW7-A nrPDB Length = 502 Score = 522 bits (1345), Expect = e-148, Method: Composition-based stats. Identities = 162/534 (30%), Positives = 236/534 (44%), Gaps = 57/534 (10%) Query: 87 VFNLTEVDNWMGPDGVVKEKVMLINGNIMGPNIVANWGDTVEVTVINNL----VTNGTSI 142 V +LT + + PDG + V+ NG GP I N GD ++ VI+NL + T+I Sbjct: 5 VTDLTISNADVTPDGFTRAAVV-ANGVFPGPLITGNKGDNFQINVIDNLTNATMLKTTTI 63 Query: 143 HWHGIHQKDTNLHDGANGVTECPIPPKGGQRTYRWRA-RQYGTSWYHSHFSAQYGNGVVG 201 HWHG+ Q TN DG V +CPI G Y + Q GT WYHSH S QY +G+ G Sbjct: 64 HWHGLFQHGTNWADGPAFVNQCPIA-SGNSFLYDFTVPDQAGTFWYHSHLSTQYCDGLRG 122 Query: 202 TIQINGPA---SLPYDIDL--GVFPITDYYYRAADDLVHFTQNNAPPFSDNVLINGTAVN 256 + + P+ + YD+D V ++D+Y+ AA F PP +D+VLING Sbjct: 123 PLVVYDPSDPYASMYDVDDDTTVITLSDWYHTAAKLGPAF-----PPNADSVLINGLGRF 177 Query: 257 PNTGEGQYANVTLTPGKRHRLRILNTSTENHFQVSLVNHTMTVIAADMVPVNAMTVDSLF 316 A +T+ KR+R R+++ S + +F S+ H MT+I D V + VDS+ Sbjct: 178 AGGNASDLAVITVEQNKRYRFRLVSLSCDPNFTFSIDGHNMTIIEVDGVNHEPLEVDSIQ 237 Query: 317 LAVGQRYDVVIDASRAPDNYWFNVTFG-GQAACGGSLNPHPAAIFHYAGAPGGLPTDEGT 375 + QRY V++A+++ DNYW G G LN +AI Y+GA PT T Sbjct: 238 IFASQRYSFVLNATQSVDNYWIRAIPNTGTIDTTGGLN---SAILRYSGADIVDPTANAT 294 Query: 376 PPVDHQCLDTLDVRPVVPRSVPVNSFVKRPDNTLPVALDLTGTPLFVWKVNGSDINVDWG 435 V L D+ P+ + P + V D + + GT F+ ++ + Sbjct: 295 TSV--IPLVETDLVPLDSPAAPGDPVVGGVDLAMNLDFSFNGTNFFIN----NETLIPPT 348 Query: 436 KPIIDYILTGNTSYPVSDNIVQVDAVDQWTYWLIE--------NDPEGPFSLPHPMHLHG 487 P++ IL+G S SD + IE N PHP HLHG Sbjct: 349 VPVLLQILSGAQS--ASDLLPTGSVYTLPLNSTIELSFPITTVNGVTNAPGAPHPFHLHG 406 Query: 488 HDFLVLGRSPDVPAASQQRFVFDPAVDLARLNGDNPPRRDTTMLP-AGGWLLLAFRTDNP 546 H F V+ + N NP RRDT G + + F TDN Sbjct: 407 HAFSVVRSAGSSD-----------------YNYVNPVRRDTVSTGNPGDNVTIRFTTDNA 449 Query: 547 GAWLFHCHIAWHVSGGLSVDFLERPADLRQRISQEDEDDFNRVCDEWRAYWPTN 600 G W HCHI +H+ G ++ F E D ++ +C + A P++ Sbjct: 450 GPWFLHCHIDFHLEAGFAIVFAEDTPD--TASVNPVPTAWSDLCPTYDALDPSD 501 >1V10-A nrPDB Length = 521 Score = 522 bits (1344), Expect = e-148, Method: Composition-based stats. Identities = 169/548 (30%), Positives = 242/548 (44%), Gaps = 51/548 (9%) Query: 75 VSTPDTGVTQSYVFNLTEVDNWMGPDGVVKEKVMLINGNIMGPNIVANWGDTVEVTVINN 134 +S + + +L ++ + PDG + G + P I N D ++ VI+ Sbjct: 13 LSLTSLSLAATVALDLHILNANLDPDGTGARSAVTAEGTTIAPLITGNIDDRFQINVIDQ 72 Query: 135 L----VTNGTSIHWHGIHQKDTNLHDGANGVTECPIPPKGGQRTYRWRAR-QYGTSWYHS 189 L + TSIHWHG Q T DG V +CPI P Y + Q GT WYHS Sbjct: 73 LTDANMRRATSIHWHGFFQAGTTEMDGPAFVNQCPIIPN-ESFVYDFVVPGQAGTYWYHS 131 Query: 190 HFSAQYGNGVVGTIQI---NGPASLPYDIDL--GVFPITDYYYRAADDLVHFTQNNAPPF 244 H S QY +G+ G + N P YD+D V I D+Y+ + ++ N APP Sbjct: 132 HLSTQYCDGLRGAFVVYDPNDPHLSLYDVDDASTVITIADWYH-SLSTVLFPNPNKAPPA 190 Query: 245 SDNVLINGTAVN-PNTGEGQYANVTLTPGKRHRLRILNTSTENHFQVSLVNHTMTVIAAD 303 D LING N N GQ A V++ GKR+R RI++TS ++ S+ H MTVI D Sbjct: 191 PDTTLINGLGRNSANPSAGQLAVVSVQSGKRYRFRIVSTSCFPNYAFSIDGHRMTVIEVD 250 Query: 304 MVPVNAMTVDSLFLAVGQRYDVVIDASRAPDNYWFNVTFGGQAACGGSLNPHPAAIFHYA 363 V +TVDSL + GQRY VV++A++A NYW G +AIF Y Sbjct: 251 GVSHQPLTVDSLTIFAGQRYSVVVEANQAVGNYWIRAN--PSNGRNGFTGGINSAIFRYQ 308 Query: 364 GAPGGLPTDEGTPPVDHQCLDTLDVRPVVPRSVPVNSFVKRPDNTLPVALDLTGTPLFVW 423 GA PT L+ ++ P++ P N D L + + T + Sbjct: 309 GAAVAEPTTSQN---SGTALNEANLIPLINPGAPGNPVPGGADINLNLRIGRNATTA-DF 364 Query: 424 KVNGSDINVDWGKPIIDYILTGNTSYPVSDNIVQVDAVDQWTYWLIENDPEGPFSLPHPM 483 +NG+ + P++ IL+G T+ +D + + +IE P HP Sbjct: 365 TINGAPF-IPPTVPVLLQILSGVTN--PNDLLPGGAVISLPANQVIE--ISIPGGGNHPF 419 Query: 484 HLHGHDFLVLGRSPDVPAASQQRFVFDPAVDLARLNGDNPPRRDTTMLPAGG-WLLLAFR 542 HLHGH+F V+ + N NP RRD + GG + F Sbjct: 420 HLHGHNFDVVRTPG-----------------SSVYNYVNPVRRDVVSIGGGGDNVTFRFV 462 Query: 543 TDNPGAWLFHCHIAWHVSGGLSVDFLERPADLRQRISQEDEDDFNRVCDEWRAYWPTNPY 602 TDNPG W HCHI WH+ GL+V F E ++ I+ ++ +C ++ A P Sbjct: 463 TDNPGPWFLHCHIDWHLEAGLAVVFAEDIPNI--PIANAISPAWDDLCPKYNANNP---- 516 Query: 603 PKIDSGLK 610 DSGL Sbjct: 517 ---DSGLA 521 >3T6Z-A nrPDB Length = 495 Score = 519 bits (1336), Expect = e-147, Method: Composition-based stats. Identities = 151/524 (28%), Positives = 234/524 (44%), Gaps = 51/524 (9%) Query: 87 VFNLTEVDNWMGPDGVVKEKVMLINGNIMGPNIVANWGDTVEVTVINNL----VTNGTSI 142 V +L V+ + PDG V+ V G GP I N GD ++ N L + TSI Sbjct: 6 VTDLHIVNADIVPDGFVRPAVN-AGGTFPGPVIAGNVGDNFQIVTFNQLIECSMLVDTSI 64 Query: 143 HWHGIHQKDTNLHDGANGVTECPIPPKGGQRTYRWRAR-QYGTSWYHSHFSAQYGNGVVG 201 HWHG QK TN DG +T+CPI G +Y + GT WYHSH + QY +G+ G Sbjct: 65 HWHGEFQKGTNWADGPAFITQCPII-VGNSFSYNFNVPGMAGTYWYHSHLTTQYCDGLRG 123 Query: 202 TIQI---NGPASLPYDIDL--GVFPITDYYYRAADDLVHFTQNNAPPFSDNVLINGTAV- 255 + N P + YD+D + + D+Y+ A ++ +D+ LI+G Sbjct: 124 PFVVYDPNDPDANLYDVDDDTTIITLADWYHVLAKEMGA----GGAITADSTLIDGLGRT 179 Query: 256 NPNTGEGQYANVTLTPGKRHRLRILNTSTENHFQVSLVNHTMTVIAADMVPVNAMTVDSL 315 + N + +T+ GKR+R+R+++ S + ++ S+ H MT+I D V +TVD + Sbjct: 180 HVNVAAVPLSVITVEVGKRYRMRLVSISCDPNYDFSIDGHDMTIIETDGVDSQELTVDEI 239 Query: 316 FLAVGQRYDVVIDASRAPDNYWF--NVTFGGQAACGGSLNPHPAAIFHYAGAPGGLPTDE 373 + QRY V++A++ NYW N GG+ GG +AI Y GA P Sbjct: 240 QIFAAQRYSFVLNANQPVGNYWIRANPNSGGEGFDGG----INSAILRYDGATTADPVTV 295 Query: 374 GTPPVDHQCLDTLDVRPVVPRSVPVNSFVKRPDNTLPVALDLTGTPLFVWKVNGSDINVD 433 + V +CL D+ P+ VP N D L ++L + V+ + V Sbjct: 296 AST-VHTKCLIETDLHPLSRNGVPGNPHQGGADCNLNLSLGFACGNFVINGVSFTPPTV- 353 Query: 434 WGKPIIDYILTGNTSYPVSDNIVQVDAVDQWTYWLIE-NDPEGPFSLPHPMHLHGHDFLV 492 P++ I +G +D + + + IE P G PHP HLHGHDF V Sbjct: 354 ---PVLLQICSGA--NTAADLLPSGSVISLPSNSTIEIALPAGAAGGPHPFHLHGHDFAV 408 Query: 493 LGRSPDVPAASQQRFVFDPAVDLARLNGDNPPRRDTTMLPA-GGWLLLAFRTDNPGAWLF 551 + + + N D+P RD + G + + F TDNPG W Sbjct: 409 SESASN-----------------STSNYDDPIWRDVVSIGGVGDNVTIRFCTDNPGPWFL 451 Query: 552 HCHIAWHVSGGLSVDFLERPADLRQRISQEDEDDFNRVCDEWRA 595 HCHI WH+ G ++ F E + + + ++ +C + + Sbjct: 452 HCHIDWHLDAGFAIVFAEDIPN--TASANPVPEAWSNLCPSYDS 493 >5EHF-A nrPDB Length = 497 Score = 515 bits (1325), Expect = e-146, Method: Composition-based stats. Identities = 162/529 (30%), Positives = 234/529 (44%), Gaps = 52/529 (9%) Query: 87 VFNLTEVDNWMGPDGVVKEKVMLINGNIMGPNIVANWGDTVEVTVINNL----VTNGTSI 142 V +L V+ + PDG + V L G GP I N GD ++ VI+ L + TSI Sbjct: 5 VADLKIVNANIQPDGFTRPAV-LAGGTFPGPLIKGNKGDNFQLNVIDELENEDMLKSTSI 63 Query: 143 HWHGIHQKDTNLHDGANGVTECPIPPKGGQRTYRWRA-RQYGTSWYHSHFSAQYGNGVVG 201 HWHG Q TN DG V +CPI G Y + Q GT WYHSH S QY +G+ G Sbjct: 64 HWHGFFQHGTNWADGPAFVNQCPIT-TGHSFLYNFHVPDQAGTFWYHSHLSTQYCDGLRG 122 Query: 202 TIQINGPASLP---YDIDL--GVFPITDYYYRAADDLVHFTQNNAPPFSDNVLINGTAVN 256 + + P YD+D V + D+Y+ A + P D+ LING Sbjct: 123 PMVVYDPHDPLKQLYDVDDESTVMTLADWYHTLAR-----QEPPGPVTPDSTLINGLGRA 177 Query: 257 PN-TGEGQYANVTLTPGKRHRLRILNTSTENHFQVSLVNHTMTVIAADMVPVNAMTVDSL 315 P T + A +T+ G R+R+R++N S E ++ S+ NH +TVI AD V ++TV SL Sbjct: 178 PGQTTPSELAVLTVKRGTRYRIRLINISCEPNYHYSIDNHDLTVIEADGVSTQSLTVSSL 237 Query: 316 FLAVGQRYDVVIDASRAPDNYWFN--VTFGGQAACGGSLNPHPAAIFHYAGAPGGLPTDE 373 + GQRY +++A++ NYW G +N +AI Y GAP P Sbjct: 238 TIFAGQRYSFILNANQPVGNYWIRAQPNDAADVTFNGGIN---SAILRYEGAPVAEPNTT 294 Query: 374 GTPPVDHQCLDTLDVRPVVPRSVPVNSFVKRPDNTLPVALDLTGTPLFVWKVNGSDINVD 433 P D+ L +++RP V VP D + GT V V+ V Sbjct: 295 AGP--DNTPLLEVNIRPFVFTPVPGQPHAGGADFVKNLLFSFNGTNFQVDNVSF----VP 348 Query: 434 WGKPIIDYILTGNTSYPVSDNIVQVDAVDQWTYWLIE-NDPEGPFSLPHPMHLHGHDFLV 492 PI+ IL+G + D + + +IE + P G HP+HLHGH+F V Sbjct: 349 PTVPILLQILSGA--HTAQDLMPAGSIIPLPKNAVIEFSMPGGVVGGGHPIHLHGHNFWV 406 Query: 493 LGRSPDVPAASQQRFVFDPAVDLARLNGDNPPRRDTTMLP-AGGWLLLAFRTDNPGAWLF 551 + + + + N ++P RD + G + + F T+NPG W Sbjct: 407 IRSA-----------------NSSVYNYNDPVIRDVVNIGTTGDNVTIRFETNNPGPWFL 449 Query: 552 HCHIAWHVSGGLSVDFLERPADLRQRISQEDEDDFNRVCDEWRAYWPTN 600 HCHI WH+ G +V E + +N +C + A P N Sbjct: 450 HCHIDWHLDLGFAVVMAEDIP--DAAAANPVPAAWNELCPLYDALTPGN 496 >5Z1X-A nrPDB Length = 495 Score = 514 bits (1323), Expect = e-146, Method: Composition-based stats. Identities = 156/524 (29%), Positives = 228/524 (43%), Gaps = 54/524 (10%) Query: 87 VFNLTEVDNWMGPDGVVKEKVMLINGNIMGPNIVANWGDTVEVTVINNL----VTNGTSI 142 V ++ V+ + PDG + V L G GP I GD ++ V+++L + TSI Sbjct: 5 VTDIHIVNKDIAPDGFSRPSV-LAGGTFPGPLITGQKGDNFKLNVVDDLTDASMLKSTSI 63 Query: 143 HWHGIHQKDTNLHDGANGVTECPIPPKGGQRTYRWRA-RQYGTSWYHSHFSAQYGNGVVG 201 HWHG QK TN DG V +CPI G Y ++ Q GT WYHSH S QY +G+ G Sbjct: 64 HWHGFFQKGTNWADGPAFVNQCPIS-TGNSFLYNFQVPDQAGTYWYHSHLSTQYCDGLRG 122 Query: 202 TIQINGP---ASLPYDIDL--GVFPITDYYYRAADDLVHFTQNNAPPFSDNVLINGTAVN 256 + P YD+D V + D+Y+ A +V +D LING N Sbjct: 123 AFVVYDPTDPHKALYDVDDESTVITLADWYHTLARQIV------GVAIADTTLINGLGRN 176 Query: 257 PNTGE-GQYANVTLTPGKRHRLRILNTSTENHFQVSLVNHTMTVIAADMVPVNAMTVDSL 315 N A + + GKR+RLR+++ S + ++ S+ NH +I D V + VDS+ Sbjct: 177 TNGPADAALAVINVEAGKRYRLRLVSISCDPNYVFSIDNHDFNIIEVDGVNSKPLNVDSI 236 Query: 316 FLAVGQRYDVVIDASRAPDNYWF--NVTFGGQAACGGSLNPHPAAIFHYAGAPGGLPTDE 373 + GQRY V++A++ NYW N G GG +AI Y GAP P Sbjct: 237 QIFAGQRYSAVLNANQPVGNYWVRANPNLGTTGFTGG----INSAILRYKGAPVAEP--T 290 Query: 374 GTPPVDHQCLDTLDVRPVVPRSVPVNSFVKRPDNTLPVALDLTGTPLFVWKVNGSDINVD 433 T + L ++RP+V VP ++ D + L + +NG+ Sbjct: 291 TTQTTSTKPLQEPNLRPLVSMPVPGSATPGGVDVVHNLILGFSAGKF---TINGAAFT-P 346 Query: 434 WGKPIIDYILTGNTSYPVSDNIVQVDAVDQWTYWLIE-NDPEGPFSLPHPMHLHGHDFLV 492 P++ IL+G T+ D + + IE G PHP HLHGH+F V Sbjct: 347 PSVPVLLQILSGTTN--AQDLLPSGSVITLPIGKTIELTLAAGVLGGPHPFHLHGHNFHV 404 Query: 493 LGRSPDVPAASQQRFVFDPAVDLARLNGDNPPRRDTTMLPA-GGWLLLAFRTDNPGAWLF 551 + + N +P RD G + + F TDNPG W Sbjct: 405 VRSAGQTTP-----------------NYVDPIVRDVVNTGGTGDNVTIRFTTDNPGPWFL 447 Query: 552 HCHIAWHVSGGLSVDFLERPADLRQRISQEDEDDFNRVCDEWRA 595 HCHI WH+ G +V F E + + D+N +C+ + A Sbjct: 448 HCHIDWHLEAGFAVVFAEGVN--QTNAANPTPADWNNLCNIYNA 489 >2HZH-A nrPDB Length = 499 Score = 510 bits (1312), Expect = e-144, Method: Composition-based stats. Identities = 154/530 (29%), Positives = 238/530 (44%), Gaps = 64/530 (12%) Query: 88 FNLTEVDNWMGPDGVVKEKVMLINGNIMGPNIVANWGDTVEVTVINNL----VTNGTSIH 143 NL + + DG ++ V+ +NG GP I N GD ++ VINNL + TS+H Sbjct: 6 ANLVVTNAAVAADGHSRDAVV-VNGGTPGPLITGNKGDQFQLNVINNLTNFTMLKSTSVH 64 Query: 144 WHGIHQKDTNLHDGANGVTECPIPPKGGQRTYRWRAR-QYGTSWYHSHFSAQYGNGVVGT 202 WHG QK TN DG V +CPI G Y + Q GT WYHSH S QY +G G Sbjct: 65 WHGFFQKGTNWADGPAFVNQCPIA-AGSSFLYDFSTPIQAGTFWYHSHLSTQYCDGDRGP 123 Query: 203 IQI---NGPASLPYDIDL--GVFPITDYYYRAADDLVHFTQNNAPPFSDNVLINGTAVNP 257 + N P++ YD+D V +TD+Y+ AA + P +D LING P Sbjct: 124 FVVYDPNDPSANLYDVDNLNTVITLTDWYHTAAQNGP-----AKPGGADATLINGQGRGP 178 Query: 258 NTGEGQYANVTLTPGKRHRLRILNTSTENHFQVSLVNHTMTVIAADMVPVNAMTVDSLFL 317 ++ A +++T GKR+R R+++ S + ++ S+ H MT+I D + V + V + + Sbjct: 179 SSPSADLAVISVTAGKRYRFRLVSNSCDPNYTFSIDGHQMTIIQVDSINVQPLVVLKIQI 238 Query: 318 AVGQRYDVVIDASRAPDNYWFNVTFGGQAACGGSLNPHPAAIFHYAGAPGGLPTDEGTPP 377 QRY +++A++A +NYW G N +AI Y+GA PT T Sbjct: 239 YAAQRYSFILNANQAVNNYWIRAN--PNQGNVGFTNGINSAILRYSGAAATQPTTSQTSS 296 Query: 378 VDHQCLDTLDVRPVVPRSVPVNSFVKRPDNTLPVALDLTGTPLFVWKVNGSDINVDWGKP 437 V Q LD ++ P+ +VP + + + A + GT FV + V P Sbjct: 297 V--QPLDQTNLHPLTATAVPGSPVAGGVNLAINQAFNFNGTNHFVDGASF----VPPTVP 350 Query: 438 IIDYILTGNTSYPVSDNIVQVDAVDQWTYWLIENDPEGPFSL---------PHPMHLHGH 488 ++ I++G S D + + + +D S PHP HLHGH Sbjct: 351 VLSQIVSGAQS--------AADLLASGLVYSLPSDANIEISFPATSAAAGGPHPFHLHGH 402 Query: 489 DFLVLGRSPDVPAASQQRFVFDPAVDLARLNGDNPPRRDTTMLP---AGGWLLLAFRTDN 545 F V+ + N ++P RDT A + + F+T+N Sbjct: 403 AFAVVRSAG-----------------STTYNYNDPIFRDTVSTGTPAANDNVTIRFKTNN 445 Query: 546 PGAWLFHCHIAWHVSGGLSVDFLERPADLRQRISQEDEDDFNRVCDEWRA 595 PG W HCHI +H+ G +V F + D+ + + ++ +C + A Sbjct: 446 PGPWFLHCHIDFHLEAGFAVVFAQDIPDVAS--ANPTPNAWSDLCPVYDA 493 >5LM8-A nrPDB Length = 549 Score = 494 bits (1272), Expect = e-140, Method: Composition-based stats. Identities = 193/562 (34%), Positives = 285/562 (50%), Gaps = 40/562 (7%) Query: 65 DGFDINTDYEVSTPDTGVTQSYVFNLTEVDNWMGPDGVVKEKVMLINGNIMGPNIVANWG 124 G+DINT+Y + P T V + Y F+ V+ DGV + V+L+NG GP I ANWG Sbjct: 5 QGYDINTNYYETIPQTNVVREYWFD--IVNTTAALDGV-ERPVLLVNGQFPGPTIEANWG 61 Query: 125 DTVEVTVINNLVTNGTSIHWHGIHQKDTNLHDGANGVTECPIPPKGGQRTYRWRARQYGT 184 DTV+V V N + NGT+IH+HGI Q N DG +T+CP+PP TY WRA +YG+ Sbjct: 62 DTVKVHVTNRMENNGTAIHFHGIRQLYNNQMDGVAALTQCPVPPN-SSYTYVWRAEEYGS 120 Query: 185 SWYHSHFSAQYGNGVVGTIQINGPASLPYDIDLGVFPITDYYYRAADDLVH-FTQNNAPP 243 SWYHSHFS Q GV G I I+GP++ YD DLG+ + D+ ++ D++ ++ PP Sbjct: 121 SWYHSHFSLQAWEGVFGGILIHGPSTAEYDHDLGMVFLNDWSHQTVDEMYQSVLESQNPP 180 Query: 244 FSDNVLINGTAV---NPNTGEGQYANVTLTPGKRHRLRILNTSTENHFQVSLVNHTMTVI 300 LING+ + N G+ PG+R+RLR++N + HF+ S+ NH +TVI Sbjct: 181 HFQTGLINGSNIWVTADNQTVGRRFQTEFVPGQRYRLRLVNAAMHTHFRFSIDNHDLTVI 240 Query: 301 AADMVPVNAMTVDSLFLAVGQRYDVVIDASRAPDNYWFNVTFGGQAACGGSLNP-HPAAI 359 A+D VP+ T +++ + +GQRYD+++ A++APDNYW Q+ C + N + + Sbjct: 241 ASDFVPIVPFTTNNVPIGMGQRYDIIVTANQAPDNYWIRAI--PQSFCSDNANSDNIKGV 298 Query: 360 FHYAG-APGGLPTDEGTPPVDHQCLDTLDVRPVVPRSVPVNSFVKRPDNTLPVALD-LTG 417 HY G A PT D + +VP V Sbjct: 299 LHYEGAADNSDPTSTKWDYGDDIQCLDFSLDELVPWLALDADIGGAQMAESDVDFTPFGD 358 Query: 418 TPLFVWKVNGSDINVDWGKPIIDYILT--GNTSYPVSDNIVQVDAVDQWTYWLIENDPEG 475 PL++W + G+ +N+ W P + + S +++ ++WT +++ D Sbjct: 359 VPLYLWTMGGNALNISWKDPTLQQTFEDPDKMDWKASQGVIEAAIPNKWTVLVVQTD--- 415 Query: 476 PFSLPHPMHLHGHDFLVLGRSPDVPAASQQRFVFDPAVDLARLNGDNPPRRDTTML---- 531 +PHP+HLHGHDF +L +Q F+P L NPPRRDT ++ Sbjct: 416 -LPVPHPIHLHGHDFYLL---------AQGFGQFNPQN--VTLKTHNPPRRDTALMTAAT 463 Query: 532 ---PAGGWLLLAFRTDNPGAWLFHCHIAWHVSGGLSVDFLERPADLRQRISQEDEDDFNR 588 GG++++ F DNPG WL HCHI +H + G + +ER ++ S ED Sbjct: 464 PENGGGGYMVIGFPADNPGVWLIHCHIGFHATEGFAQQIVERQSEFNTFFS---EDLLEN 520 Query: 589 VCDEWRAYWPTNPYPKIDSGLK 610 CD W Y NPY L Sbjct: 521 TCDAWDEYAKVNPYGHQYRALA 542 >1HFU-A nrPDB Length = 503 Score = 490 bits (1260), Expect = e-139, Method: Composition-based stats. Identities = 158/526 (30%), Positives = 237/526 (45%), Gaps = 50/526 (9%) Query: 87 VFNLTEVDNWMGPDGVVKEKVMLINGNIMGPNIVANWGDTVEVTVINNL----VTNGTSI 142 V +T + + PDG + + L+NG + GP I D E+ V+N+L + TSI Sbjct: 6 VDTMTLTNANVSPDGFTRAGI-LVNG-VHGPLIRGGKNDNFELNVVNDLDNPTMLRPTSI 63 Query: 143 HWHGIHQKDTNLHDGANGVTECPIPPKGGQRTYRWR-ARQYGTSWYHSHFSAQYGNGVVG 201 HWHG+ Q+ TN DGA+GV +CPI P G Y++ A GT WYHSHF QY +G+ G Sbjct: 64 HWHGLFQRGTNWADGADGVNQCPISP-GHAFLYKFTPAGHAGTFWYHSHFGTQYCDGLRG 122 Query: 202 TIQI---NGPASLPYDIDL--GVFPITDYYYRAADDLVHFTQNNAPPFSDNVLINGTAVN 256 + I N P + YD D + + D+Y+ A D LING Sbjct: 123 PMVIYDDNDPHAALYDEDDENTIITLADWYHIPA------PSIQGAAQPDATLINGKGRY 176 Query: 257 PNTGEGQYANVTLTPGKRHRLRILNTSTENHFQVSLVNHTMTVIAADMVPVNAMTVDSLF 316 + + V + GK++R+R+++ S + ++Q S+ H +T+I D TVD L Sbjct: 177 VGGPAAELSIVNVEQGKKYRMRLISLSCDPNWQFSIDGHELTIIEVDGELTEPHTVDRLQ 236 Query: 317 LAVGQRYDVVIDASRAPDNYWFN--VTFGGQAACGGSLNPHPAAIFHYAGAPGGLPTDEG 374 + GQRY V+DA++ DNYW G G N +AI YAGA PT Sbjct: 237 IFTGQRYSFVLDANQPVDNYWIRAQPNKGRNGLAGTFANGVNSAILRYAGAANADPTTSA 296 Query: 375 TPPVDHQCLDTLDVRPVVPRSVPVNSFVKRPDNTLPVALDLTGTPLFVWKVNGSDINVDW 434 P + L+ D+ ++ + P D L L +G +NG+ Sbjct: 297 NP--NPAQLNEADLHALIDPAAPGIPTPGAADVNLRFQLGFSGGRF---TINGTAYE-SP 350 Query: 435 GKPIIDYILTGNTSYPVSDNIVQVDAVDQWTYWLIE-NDPEGPFSLPHPMHLHGHDFLVL 493 P + I++G S +D + + ++E P G PHP HLHGH F V+ Sbjct: 351 SVPTLLQIMSGAQS--ANDLLPAGSVYELPRNQVVELVVPAGVLGGPHPFHLHGHAFSVV 408 Query: 494 GRSPDVPAASQQRFVFDPAVDLARLNGDNPPRRDTTMLP-AGGWLLLAFRTDNPGAWLFH 552 + + N NP +RD L G + + F TDNPG W FH Sbjct: 409 RSAG-----------------SSTYNFVNPVKRDVVSLGVTGDEVTIRFVTDNPGPWFFH 451 Query: 553 CHIAWHVSGGLSVDFLERPADLRQRISQEDEDDFNRVCDEWRAYWP 598 CHI +H+ GL++ F E A+ + E + ++C+ + P Sbjct: 452 CHIEFHLMNGLAIVFAEDMANTVDANNPPVE--WAQLCEIYDDLPP 495 >1ZPU-A nrPDB Length = 534 Score = 405 bits (1040), Expect = e-113, Method: Composition-based stats. Identities = 139/526 (26%), Positives = 225/526 (42%), Gaps = 45/526 (8%) Query: 84 QSYVFNLTEVDNWMGPDGVVKEKVMLINGNIMGPNIVANWGDTVEVTVINNLVTNGTSIH 143 +++ FN T ++ DG+ V+ NG P+I N GD V++ + N + TS+H Sbjct: 1 ETHTFNWTTGWDYRNVDGLKSRPVITCNGQFPWPDITVNKGDRVQIYLTNGMNNTNTSMH 60 Query: 144 WHGIHQKDTNLHDGANGVTECPIPPKGGQRTYRWRAR-QYGTSWYHSHFSAQYGNGVVGT 202 +HG+ Q T DG +T+CPI P G Y + GT WYHSH QY +G+ G Sbjct: 61 FHGLFQNGTASMDGVPFLTQCPIAP-GSTMLYNFTVDYNVGTYWYHSHTDGQYEDGMKGL 119 Query: 203 IQINGPASLPYDIDLGV-FPITDYYYRAADDLVH-----FTQNNAPPFSDNVLINGTAVN 256 I S PYD D + ++++Y+ DL + A P N+++N T Sbjct: 120 FIIKDD-SFPYDYDEELSLSLSEWYHDLVTDLTKSFMSVYNPTGAEPIPQNLIVNNT--- 175 Query: 257 PNTGEGQYANVTLTPGKRHRLRILNTSTENHFQVSLVNHTMTVIAADMVPVNAMTVDSLF 316 + P + LRI+N + +H MTV+ D + D L+ Sbjct: 176 ------MNLTWEVQPDTTYLLRIVNVGGFVSQYFWIEDHEMTVVEIDGITTEKNVTDMLY 229 Query: 317 LAVGQRYDVVIDASRAPDNYW-----FNVTFGGQAACGGSLNPHPAAIFHYAGAPGGLPT 371 + V QRY V++ D + F+ T LN +++ A LPT Sbjct: 230 ITVAQRYTVLVHTKNDTDKNFAIMQKFDDTMLDVIPSDLQLNATSYMVYNKTAA---LPT 286 Query: 372 DEGTPPVDHQCLDTLDVRPVVPRSVPVNSFVKRPDNTLPVALDLTGTPLFVWKVNGSDIN 431 +D+ LD ++P ++ PD+ + V + + V + N Sbjct: 287 QNYVDSIDN-FLDDFYLQPYEKEAI-----YGEPDHVITVDVVMDNLKNGVNYAFFN--N 338 Query: 432 VDWGKPIIDYILTGNTSYPVSDNIVQVDAVDQWTYWLIENDPEGPFSL------PHPMHL 485 + + P + ++T +S ++N ++ + T+ ++E D L HP HL Sbjct: 339 ITYTAPKVPTLMTVLSSGDQANN-SEIYGSNTHTF-ILEKDEIVEIVLNNQDTGTHPFHL 396 Query: 486 HGHDFLVLGRSPD-VPAASQQRFVFDPAVDLARLNGDNPPRRDTTMLPAGGWLLLAFRTD 544 HGH F + R A + FDP D + P RRDT + ++ F+ D Sbjct: 397 HGHAFQTIQRDRTYDDALGEVPHSFDP--DNHPAFPEYPMRRDTLYVRPQSNFVIRFKAD 454 Query: 545 NPGAWLFHCHIAWHVSGGLSVDFLERPADLRQRISQEDEDDFNRVC 590 NPG W FHCHI WH+ GL + +E P ++ SQ+ ++ VC Sbjct: 455 NPGVWFFHCHIEWHLLQGLGLVLVEDPFGIQDAHSQQLSENHLEVC 500 >1ASO-A nrPDB Length = 552 Score = 363 bits (931), Expect = e-100, Method: Composition-based stats. Identities = 143/531 (26%), Positives = 214/531 (40%), Gaps = 89/531 (16%) Query: 107 VMLINGNIMGPNIVANWGDTVEVTVINNLVTNGTSIHWHGIHQKDTNLHDGANGVTECPI 166 VM ING GP I AN GD+V V + N L T G IHWHGI Q+ T DG +++C I Sbjct: 24 VMGINGQFPGPTIRANAGDSVVVELTNKLHTEGVVIHWHGILQRGTPWADGTASISQCAI 83 Query: 167 PPKGGQRTYRWRARQYGTSWYHSHFSAQYGNGVVGTIQINGPA----SLPYDIDLGVFPI 222 P G Y + GT +YH H Q G+ G++ ++ P YD ++ + + Sbjct: 84 NP-GETFFYNFTVDNPGTFFYHGHLGMQRSAGLYGSLIVDPPQGKKEPFHYDGEINLL-L 141 Query: 223 TDYYYRAA---DDLVHFTQNNAPPFSDNVLINGTA-------------VNPNTGEGQYAN 266 +D+++++ + + +L+NG + P +G + Sbjct: 142 SDWWHQSIHKQEVGLSSKPIRWIGEPQTILLNGRGQFDCSIAAKYDSNLEPCKLKGSESC 201 Query: 267 V----TLTPGKRHRLRILNTSTENHFQVSLVNHTMTVIAADMVPVNAMTVDSLFLAVGQR 322 ++P K +R+RI +T+ ++ NH + V+ AD V + + G+ Sbjct: 202 APYIFHVSPKKTYRIRIASTTALAALNFAIGNHQLLVVEADGNYVQPFYTSDIDIYSGES 261 Query: 323 YDVVIDASRAP-DNYWFNVTFGGQAACGGSLNPHPAAIFHYAGAPGGLPTDEGTPPVDHQ 381 Y V+I + P +NYW +V G A + P + + + LPT +PP Sbjct: 262 YSVLITTDQNPSENYWVSV---GTRARHPNTPPGLTLLNYLPNSVSKLPT---SPPPQTP 315 Query: 382 CLDTLD------VRPVVPRSVP------------------VNSFVKRPDNTLPVALDLTG 417 D D R P +N +VK N V+L L Sbjct: 316 AWDDFDRSKNFTYRITAAMGSPKPPVKFNRRIFLLNTQNVINGYVKWAIN--DVSLALPP 373 Query: 418 TPLFV----WKVNGSDINVDW----------GKPIIDYILTGNTSYPVSDNIVQVDAVDQ 463 TP ++ D N P + GN Y V VD + Q Sbjct: 374 TPYLGAMKYNLLHAFDQNPPPEVFPEDYDIDTPPTNEKTRIGNGVYQFKIGEV-VDVILQ 432 Query: 464 WTYWLIENDPEGPFSLPHPMHLHGHDFLVLGRSPDVPAASQQRFVFDPAVDLARLNGDNP 523 + EN S HP HLHGHDF VLG +A ++ + LN NP Sbjct: 433 NANMMKEN-----LSETHPWHLHGHDFWVLGYGDGKFSAEEE----------SSLNLKNP 477 Query: 524 PRRDTTMLPAGGWLLLAFRTDNPGAWLFHCHIAWHVSGGLSVDFLERPADL 574 P R+T ++ GW + F DNPG W FHCHI H+ G+ V F E + Sbjct: 478 PLRNTVVIFPYGWTAIRFVADNPGVWAFHCHIEPHLHMGMGVVFAEGVEKV 528 Score = 38.3 bits (87), Expect = 0.010, Method: Composition-based stats. Identities = 21/91 (23%), Positives = 34/91 (37%), Gaps = 7/91 (7%) Query: 531 LPAGGWLLLAFRTDNPGAWLFHCHIAWHVSGGLSVDFLERPADLRQRISQEDEDDFNRVC 590 + G F DNPG + +H H+ S GL + P ++ D + + Sbjct: 83 INPGETFFYNFTVDNPGTFFYHGHLGMQRSAGLYGSLIVDPPQGKKEPFHYDGEINLLLS 142 Query: 591 DEWRAYWPTNPYPKIDSGLKRR--RWVEESE 619 D W K + GL + RW+ E + Sbjct: 143 DWWH-----QSIHKQEVGLSSKPIRWIGEPQ 168 >4F7K-A nrPDB Length = 425 Score = 301 bits (770), Expect = 6e-82, Method: Composition-based stats. Identities = 119/477 (24%), Positives = 184/477 (38%), Gaps = 81/477 (16%) Query: 93 VDNWMGPDGVVKEKVMLINGNIMGPNIVANWGDTVEVTVINNLVTNGTSIHWHGIHQKDT 152 V+ + P+G ++ NG GP + A G+ ++ N + G+++HWHG+ + Sbjct: 11 VNAQILPEGEPATPMLGFNGGTPGPVLRARQGEVFDIR-FQNQIGEGSAVHWHGL--RID 67 Query: 153 NLHDGANGVTECPIPPKGGQRTYRWRARQYGTSWYHSHFSA--QYGNGVVGTIQINGPAS 210 N DG G+T+ + GG+ Y +RA GT WYHSH + Q G+ G + + P Sbjct: 68 NAMDGVPGMTQ-DVVEAGGEFEYSFRAPDAGTFWYHSHNRSWEQVAKGLYGPLIVEEPTP 126 Query: 211 LPYDIDLGVFPITDYYYRAADDLVHFTQNNAPPFSDNVLINGTAVNPNTGEGQYANVTLT 270 D DL + I D+ L +N L N + Sbjct: 127 PDVDHDL-IIMIDDWRITENGVLADGFENMRDQAHQGRLGN------FARALVEPVTPVR 179 Query: 271 PGKRHRLRILNTSTENHFQVSLVNHTMTVIAADMVP-VNAMTVDSLFLAVGQRYDVVIDA 329 G R RLR++N +T+ F V L V+A D +P V+ L LA QR D++ D Sbjct: 180 RGDRVRLRLINVATDRIFPVELEGVEGKVVALDGMPIVDPQEFSGLILAPAQRADIIADV 239 Query: 330 -SRAPDNYWFNVTFGGQAACGGSLNPHPAAIFHYAGAPGGLPTDEGTPPVDHQCLDTLDV 388 + AP + F G P G PV + +T Sbjct: 240 ITDAPIGFVFPTRDG--------------------------PYLLGEIPV--KGANTTRQ 271 Query: 389 RPVVPRSVPVNSFVKRPDNTLPVALDLTGTPLFVWKVNGSDINVDWGKPIIDY-ILTGNT 447 +P ++P N V PD V+L L + G ++ + ++ I N Sbjct: 272 PSEIP-ALPPNE-VTSPDMGSAVSLTL--------TMEGGAMSRRMMQGMMGGDIWAFNG 321 Query: 448 SYPVSDNIVQVDAVDQWTYWLIENDPEGPFSLPHPMHLHGHDFLVLGRSPDVPAASQQRF 507 ++D + Q + ND PH +HLHGH F +G ++ A Sbjct: 322 QSGLTDTPLHSFERGQTARIRLVNDTR----FPHGIHLHGHHFFEVGADGNLGA------ 371 Query: 508 VFDPAVDLARLNGDNPPRRDTTMLPAGGWLLLAFRTDNPGAWLFHCHIAWHVSGGLS 564 RDTT++ AG + DNPG WL HCH+ H + G+ Sbjct: 372 -----------------LRDTTLVDAGETRDIVCVFDNPGNWLLHCHMLGHQAAGMK 411 >6EVG-A nrPDB Length = 507 Score = 294 bits (751), Expect = 1e-79, Method: Composition-based stats. Identities = 101/497 (20%), Positives = 178/497 (35%), Gaps = 74/497 (14%) Query: 103 VKEKVMLINGNIMGPNIVANWGDTVEVTVINNLVTNGTSIHWHGIHQKDTNLHDGANGVT 162 + ING +GP + G+TV ++V N + GT++HWHG+ L G + V Sbjct: 52 SEAASAGINGAYLGPLVRLKNGETVTLSVENGM-DEGTTLHWHGLFVPSI-LDGGPHNVI 109 Query: 163 ECPIPPKGGQRTYRWRARQYGTS-WYHSHFSA----QYGNGVVGTIQING----PASLPY 213 G + +Q + W+H H Q G+ G + + LP Sbjct: 110 A-----AGEAWKPEVKIQQPASFNWFHPHLHGNTARQAHLGIAGLMVVTDGKDAERGLPE 164 Query: 214 DIDLGVFPITDYYYRAADDLVHFTQNNAPPFSDNVLINGTAVNPNTGEGQYANVTLTPGK 273 D + P+ R + + + L++G G + P Sbjct: 165 DYGVDDIPLVLQDRRVIEGDKVYEPDIM------DLMHGFRGGNLIVNGIVSPEARVPAS 218 Query: 274 RHRLRILNTSTENHFQVSL-VNHTMTVIAADMVPV-NAMTVDSLFLAVGQRYDVVIDASR 331 RLRILN + +F V L N + V+A+D + N V+ L ++ G+RY+V++D S+ Sbjct: 219 IVRLRILNGANARNFHVRLSDNRPLLVVASDGGFIGNPEPVERLTISPGERYEVLVDFSK 278 Query: 332 --APDNYWFNVTFGGQ----------AACGGSLNPHPAAIFHYAGAPGGLPTDEGTPPVD 379 A D + GG AA G + P + L + D Sbjct: 279 GEATDLLTYGDDSGGDDLHLMRFVVDAALQGKVTKRPDRLDGPDAPDEKLSVKRRSFFFD 338 Query: 380 HQCLDTLDVRPVVPRSVPVNSFVKRPDNTLPVALDLTGTPLFVWKVNGSDINVDWGKPII 439 + + + + + P N + + + ++G+ + D G Sbjct: 339 ERMAENMKLMMAKLSADPHAGH-----NMGNMDMGSMQSGAMDHDMHGARSSADAGP--A 391 Query: 440 DYILTGNTSYPVSDNIVQVDAVD------QWTYWLIENDPEGPFSLPHPMHLHGHDFLVL 493 LT ++ +D +D W W + +PHP H+HG F +L Sbjct: 392 LEALTSGVEMAIAGKPFDMDRIDVEAKLGSWEIWDLTTK-----EMPHPFHIHGASFRIL 446 Query: 494 GRSPDVPAASQQRFVFDPAVDLARLNGDNPPRRDTTMLPAGGWLLLAFRTDNPG--AWLF 551 + P A Q + +DT ++ +L+ F + ++F Sbjct: 447 SLNGKAPPAHQSGW------------------KDTALIDGKAEILVHFDREAVKSHPFMF 488 Query: 552 HCHIAWHVSGGLSVDFL 568 HCH+ H G+ F+ Sbjct: 489 HCHVLEHEDVGMMAQFV 505 >5B7E-A nrPDB Length = 526 Score = 289 bits (738), Expect = 3e-78, Method: Composition-based stats. Identities = 114/504 (22%), Positives = 191/504 (37%), Gaps = 102/504 (20%) Query: 109 LINGNIMGPNIVANWGDTVEVTVINNLVTNGTSIHWHGIHQKDTNLHDGANGVTECPIPP 168 NGN++GP + G V V + N L T T++HWHG+ + G G I P Sbjct: 68 GYNGNLLGPAVKLQRGKAVTVDIYNQL-TEETTLHWHGLEVPG-EVDGGPQG-----IIP 120 Query: 169 KGGQRTYRWRARQ-YGTSWYHSHFSA----QYGNGVVGTIQINGPASLP------YDIDL 217 GG+R+ Q T W+H H Q G+ G + I L + ID Sbjct: 121 PGGKRSVTLNVDQPAATCWFHPHQHGKTGRQVAMGLAGLVVIEDDEILKLMLPKQWGIDD 180 Query: 218 GVFPITDYYYRAADDLVHFTQNNAPP----FSDNVLINGTAVNPNTGEGQYANVTLTPGK 273 + D + +AD + + + F D +L NG A+ P P Sbjct: 181 VPVIVQDKKF-SADGQIDYQLDVMTAAVGWFGDTLLTNG-AIYPQ---------HAAPRG 229 Query: 274 RHRLRILNTSTENHFQVSL-VNHTMTVIAADMVPV-NAMTVDSLFLAVGQRYDVVIDASR 331 RLR+LN + N + VIA+D + + V L + +G+R++V+++ + Sbjct: 230 WLRLRLLNGCNARSLNFATSDNRPLYVIASDGGLLPEPVKVSELPVLMGERFEVLVEVN- 288 Query: 332 APDNYWFNVTFGGQAACGGSL----NPHPAAIFHYAG--APGGLPTDEGTPPVDHQCLDT 385 DN F++ + G ++ PHP A G LP DT Sbjct: 289 --DNKPFDLVTLPVSQMGMAIAPFDKPHPVMRIQPIAISASGALP-------------DT 333 Query: 386 LDVRPVVPRSVPVNSFVKRPDNTLPVALDLTGTPLFVWK--------VNGSDINVDWGKP 437 L P +P + V++ ++ LD+ G + + K ++ S + G Sbjct: 334 LSSLPALPSLEGLT--VRKLQLSMDPMLDMMGMQMLMEKYGDQAMAGMDHSQMMGHMGHG 391 Query: 438 IIDYILTGNTSYPVSDNIVQVDAVD-----------QWTYWLIENDPEGPFSLPHPMHLH 486 ++++ G N + A D Q+ W+I + + HP H+H Sbjct: 392 NMNHMNHGGKFDFHHANKINGQAFDMNKPMFAAAKGQYERWVISGVGD---MMLHPFHIH 448 Query: 487 GHDFLVLGRSPDVPAASQQRFVFDPAVDLARLNGDNPPRRDTTMLPAG-GWLLLAFRTDN 545 G F +L + PAA + + +DT + +L+ F D Sbjct: 449 GTQFRILSENGKPPAAHRAGW------------------KDTVKVEGNVSEVLVKFNHDA 490 Query: 546 PG--AWLFHCHIAWHVSGGLSVDF 567 P A++ HCH+ H G+ + F Sbjct: 491 PKEHAYMAHCHLLEHEDTGMMLGF 514 >5ZLM-A nrPDB Length = 513 Score = 279 bits (712), Expect = 3e-75, Method: Composition-based stats. Identities = 121/519 (23%), Positives = 178/519 (34%), Gaps = 91/519 (17%) Query: 102 VVKEKVMLINGNIMGPNIVANWGDTVEVTVINNLVTNGTSIHWHGIHQ------------ 149 + ++ NG GP I + V V +NNL + H IH Sbjct: 43 LPPTRLWGYNGLFPGPTIEVKRNENVYVKWMNNLPSTHFLPIDHTIHHSDSQHEEPEVKT 102 Query: 150 ----KDTNLHDGANGVTEC-------PIPPKGGQRTYRWRARQYGTS-WYHSHFSA---- 193 D ++G E P + Y + +Q G WYH H A Sbjct: 103 VVHLHGGVTPDDSDGYPEAWFSKDFEQTGPYFKREVYHYPNQQRGAILWYHDHAMALTRL 162 Query: 194 QYGNGVVGTIQINGPA----SLPYDIDLGVFPITDYYYRAADDLVHFTQNNAPPFSDNVL 249 G+VG I+ P LP D ITD R ++ +AP L Sbjct: 163 NVYAGLVGAYIIHDPKEKRLKLPSDEYDVPLLITD---RTINEDGSLFYPSAPENPSPSL 219 Query: 250 INGTAVNPNTGEGQYANVTLTP-----GKRHRLRILNTSTENHFQVSLVN-HTMTVIAAD 303 N + V GE N + P +++R R++N S + +SL N I +D Sbjct: 220 PNPSIVPAFCGETILVNGKVWPYLEVEPRKYRFRVINASNTRTYNLSLDNGGDFIQIGSD 279 Query: 304 MVPV-NAMTVDSLFLAVGQRYDVVIDASRAPDNYWFNVTFGGQAACGGSLNPHPAA-IFH 361 + ++ ++S LA +RYD++ID + ++ A CGG +NP A I Sbjct: 280 GGLLPRSVKLNSFSLAPAERYDIIIDFTAYEGE---SIILANSAGCGGDVNPETDANIMQ 336 Query: 362 YAGAPGGLPTDEGTPPVDHQCLDTLDVRPVVPRSVPVNSFVKRPDNTLPVALDLTGTPLF 421 + DE P L P V +R N L L GT Sbjct: 337 FRVTKPLAQKDESRKP------KYLASYPSVQH--------ERIQNIR--TLKLAGTQ-- 378 Query: 422 VWKVNGSDINVDWGKPIIDYILTGNTSYPVSDNIVQVDAVDQWTYWLIENDPEGPFSLPH 481 ++G+P++ L N + D + + V W I N G H Sbjct: 379 ----------DEYGRPVL---LLNNKRW--HDPVTETPKVGTTEIWSIINPTRG----TH 419 Query: 482 PMHLHGHDFLVLGRSPDVPAASQQRFVFDPAVDLARLNGDNPPRRDTTMLPAGGWLLLAF 541 P+HLH F VL R P A Q+ +DT AG L +A Sbjct: 420 PIHLHLVSFRVLDRRPFDIARYQESGELSYTGPAVPPPPSEKGWKDTIQAHAGEVLRIA- 478 Query: 542 RTDNP--GAWLFHCHIAWHVSGGLSVDFLERPADLRQRI 578 T P G +++ CHI H + RP D+ Sbjct: 479 ATFGPYSGRYVWCCHILEHEDYDMM-----RPMDITDPH 512 >2YXV-A nrPDB Length = 446 Score = 269 bits (687), Expect = 3e-72, Method: Composition-based stats. Identities = 112/485 (23%), Positives = 178/485 (36%), Gaps = 112/485 (23%) Query: 109 LINGNIMGPNIVANWGDTVEVTVINNLVTNGTSIHWHGIHQKDTNLHDGANGVTECPIPP 168 NGN++GP + G V V + N L T T++HWHG+ + G G I P Sbjct: 40 GYNGNLLGPAVKLQRGKAVTVDIYNQL-TEETTLHWHGLEVPG-EVDGGPQG-----IIP 92 Query: 169 KGGQRTYRWRARQ-YGTSWYHSHFSA----QYGNGVVGTIQINGPASLP------YDIDL 217 GG+R+ Q T W+H H Q G+ G + I L + ID Sbjct: 93 PGGKRSVTLNVDQPAATCWFHPHQHGKTGRQVAMGLAGLVVIEDDEILKLMLPKQWGIDD 152 Query: 218 GVFPITDYYYRAADDLVHFTQNNAPP----FSDNVLINGTAVNPNTGEGQYANVTLTPGK 273 + D + +AD + + + F D +L NG A+ P P Sbjct: 153 VPVIVQDKKF-SADGQIDYQLDVMTAAVGWFGDTLLTNG-AIYPQ---------HAAPRG 201 Query: 274 RHRLRILNTSTENHFQVSL-VNHTMTVIAADMVPV-NAMTVDSLFLAVGQRYDVVIDASR 331 RLR+LN + N + VIA+D + + V L + +G+R++V+++ + Sbjct: 202 WLRLRLLNGCNARSLNFATSDNRPLYVIASDGGLLPEPVKVSELPVLMGERFEVLVEVN- 260 Query: 332 APDNYWFNVTFGGQAACGGSL----NPHPAAIFHYAG--APGGLPTDEGTPPVDHQCLDT 385 DN F++ + G ++ PHP A G LP DT Sbjct: 261 --DNKPFDLVTLPVSQMGMAIAPFDKPHPVMRIQPIAISASGALP-------------DT 305 Query: 386 LDVRPVVPRSVPVNSFVKRPDNTLPVALDLTGTPLFVWKVNGSDINVDWGKPIIDYILTG 445 L P +P L +++D K+NG D KP+ Sbjct: 306 LSSLPALPS------LEGLTVRKLQLSMDGGAN-----KINGQAF--DMNKPMF------ 346 Query: 446 NTSYPVSDNIVQVDAVDQWTYWLIENDPEGPFSLPHPMHLHGHDFLVLGRSPDVPAASQQ 505 A Q+ W+I + + HP H+HG F +L + PAA + Sbjct: 347 ------------AAAKGQYERWVISGVGD---MMLHPFHIHGTQFRILSENGKPPAAHRA 391 Query: 506 RFVFDPAVDLARLNGDNPPRRDTTMLPAG-GWLLLAFRTDNPG--AWLFHCHIAWHVSGG 562 + +DT + +L+ F D P A++ HCH+ H G Sbjct: 392 GW------------------KDTVKVEGNVSEVLVKFNHDAPKEHAYMAHCHLLEHEDTG 433 Query: 563 LSVDF 567 + + F Sbjct: 434 MMLGF 438 >3AW5-A nrPDB Length = 448 Score = 264 bits (673), Expect = 1e-70, Method: Composition-based stats. Identities = 111/481 (23%), Positives = 178/481 (37%), Gaps = 93/481 (19%) Query: 113 NIMGPNIVANWGDTVEVTVINNLVTNGTSIHWHGIHQKDTNLHDGANGVTECPIPPKGGQ 172 ++ P I+ G V++T+ N L T T +HWHG D N H+ A+ I P G Sbjct: 34 GVLNPTIILRRGQRVDMTLKNKL-TEPTIVHWHGF---DVNWHNDAH--PSFAITP-GES 86 Query: 173 RTYRWRA-RQYGTSWYHSH----FSAQYGNGVVGTIQING---PASLPYDIDLGVFPITD 224 Y + + GT YH H + Q+ G +G + + Y ++ I+D Sbjct: 87 YNYSFDVVNRAGTYLYHPHPHGLTAKQFYMGQLGLVIVEDSGSDLGFKYGVNDLPLVISD 146 Query: 225 YYYRAADDLVHFT--QNNAPPFSDNVLINGTAVNPNTGEGQYANVTLTPGKRHRLRILNT 282 + + + T + A + VL+NG V G +RLR++N Sbjct: 147 RRFIGGAPVYNPTPMEMIAGFLGNAVLVNGV----------KDAVFKLSGGSYRLRLVNG 196 Query: 283 STENHFQVSLVNHTMTVIAADMVPVN------AMTVDSLFLAVGQRYDVVIDASRAPDNY 336 S + +S+V V+ ++ V+ + V +LFLA +R +VV++ Y Sbjct: 197 SNARLYMLSIVKKNGDVVPMRLIAVDQGFLARPIEVRALFLAPAERAEVVVELGEGV--Y 254 Query: 337 WFNVTFGGQAACGGSLNPHPAAIFHYAGAPGGLPTDEGTPPVDHQCLDTLDVRPVVPRSV 396 T P H G E P + T V +V Sbjct: 255 LLKNT--------------PFDPMHLEMGHG---MQEALPEGSEYTIATFLVEG-KGEAV 296 Query: 397 PVNSF------VKRPDNTLPVALDLTGTPLFVWKVNGSDINVDWGKPIIDYILTGNTSYP 450 PV + +P T AL L+G W +NG + Sbjct: 297 PVEALSDPPPEPPKPTRTRRFALSLSGMQ---WTING-------------------MFWN 334 Query: 451 VSDNIVQVDAVDQWTYWLIENDPEGPFSLPHPMHLHGHDFLVLGRSPDVPAASQQRFVFD 510 S+ + + +V+ W I ND S+PHPMHLHG ++ R R V + Sbjct: 335 ASNPLFEHVSVEGVELWEIVNDKA---SMPHPMHLHGFPMWIIERKDSP------RQVAE 385 Query: 511 PAVDLARLNGDNPPRRDTTMLPAGGWL--LLAFRTDNPGAWL-FHCHIAWHVSGGLSVDF 567 AVD + +DT ++ G + ++ F G FHCH H GG+ ++ Sbjct: 386 LAVDNRGRLPTDLGLKDTVLIWPGETVKIVVNFDAKKRGQLFPFHCHNLEHEDGGMMINI 445 Query: 568 L 568 Sbjct: 446 A 446 >4E9V-A nrPDB Length = 339 Score = 243 bits (620), Expect = 1e-64, Method: Composition-based stats. Identities = 78/291 (26%), Positives = 118/291 (40%), Gaps = 27/291 (9%) Query: 88 FNLTEVDNWMGPDGVVKEKVMLINGNIMGPNIVANWGDTVEVTVINNLVTNGTSIHWHGI 147 F++T + + + KV NG + GP I GD V V V NN +IHWHG+ Sbjct: 6 FDMTIEEVTIKVAPGLDYKVFGFNGQVPGPLIHVQEGDDVIVNVTNNTSL-PHTIHWHGV 64 Query: 148 HQKDTNLHDGANGVTECPIPPKGGQRTYRWRARQYGTSWYHSHFSAQYG---NGVVGTIQ 204 HQK T DG GVT+ PI G TY+++A + GT WYH H + G+ G + Sbjct: 65 HQKGTWRSDGVPGVTQQPI-EAGDSYTYKFKADRIGTLWYHCHVNVNEHVGVRGMWGPLI 123 Query: 205 INGPASLPYDIDLGVFPITDYYYRAADDLVHFTQNNAPPFSDNVLINGTAVNPNTGEGQY 264 ++ LP + R D++ +D GT +N Sbjct: 124 VDPKQPLPIE------------KRVTKDVIMMMSTWESAVADKYGEGGTPMNVADYFSVN 171 Query: 265 AN-------VTLTPGKRHRLRILNTSTENHFQVSLVNHTMTVIAADMVPVN-AMTVDSLF 316 A + + G ++R H S H M V D +P++ D++ Sbjct: 172 AKSFPLTQPLRVKKGDVVKIRFFGAGGGIHAMHS-HGHDMLVTHKDGLPLDSPYYADTVL 230 Query: 317 LAVGQRYDVVIDASRAPDNYWFNVTFGGQAACGGSLNPHPAAIFHYAGAPG 367 ++ G+RYDV+I+A P + F+ GG P + Y G P Sbjct: 231 VSPGERYDVIIEADN-PGRFIFHDHVDTHVTAGGKHPGGPITVIEYDGVPV 280 Score = 56.0 bits (133), Expect = 5e-08, Method: Composition-based stats. Identities = 45/270 (16%), Positives = 81/270 (30%), Gaps = 42/270 (15%) Query: 314 SLFLAVGQRYDVVIDASRAPDNYWFNVTFGGQAACGGSLNPHPAAIFHYAGAPGGLPT-D 372 ++ +A G Y V + +V G + N H+ G Sbjct: 14 TIKVAPGLDYKVF-GFNGQVPGPLIHVQEGDDVIVNVTNNTSLPHTIHWHGVHQKGTWRS 72 Query: 373 EGTPPVDHQCLDTLDVRPVVPRSVPVNSFVKRPDNTLPVALDLTGTPLFVWKVNGSDINV 432 +G P V Q ++ D ++ + + + + + G + + + Sbjct: 73 DGVPGVTQQPIEAGDSYTYKFKADRIGTLWYHCHVNVNEHVGVRGMWGPLIVDPKQPLPI 132 Query: 433 DWGKPIIDYILTGNTSYPVSDNIVQVDAVDQWTYWLIENDPEGPFSLP------------ 480 + ++ V+D + + N P + P Sbjct: 133 EKRVTKDVIMMMSTWESAVADKYGEGGTPMNVADYFSVNAKSFPLTQPLRVKKGDVVKIR 192 Query: 481 --------HPMHLHGHDFLVLGRSPDVPAASQQRFVFDPAVDLARLNGDNPPRRDTTMLP 532 H MH HGHD LV + L D+P DT ++ Sbjct: 193 FFGAGGGIHAMHSHGHDMLVTHKDG--------------------LPLDSPYYADTVLVS 232 Query: 533 AGGWLLLAFRTDNPGAWLFHCHIAWHVSGG 562 G + DNPG ++FH H+ HV+ G Sbjct: 233 PGERYDVIIEADNPGRFIFHDHVDTHVTAG 262 >3G5W-A nrPDB Length = 318 Score = 225 bits (572), Expect = 7e-59, Method: Composition-based stats. Identities = 63/287 (21%), Positives = 108/287 (37%), Gaps = 13/287 (4%) Query: 88 FNLTEVDNWMGPDGVVKEKVMLINGNIMGPNIVANWGDTVEVTVINNLVTNGTSIHWHGI 147 F+L+ D + G NG + P I GD V V V N + T +IHWHG+ Sbjct: 5 FDLSIEDTRIVLVGKRDFHTFAFNGQVPAPLIHVMEGDDVTVNVTN-MTTLPHTIHWHGM 63 Query: 148 HQKDTNLHDGANGVTECPIPPKGGQRTYRWRARQYGTSWYHSHFSAQYG---NGVVGTIQ 204 Q+ T DG T+ I P G TY+++A GT WYH H + G+ G + Sbjct: 64 LQRGTWQSDGVPHATQHAIEP-GDTFTYKFKAEPAGTMWYHCHVNVNEHVTMRGMWGPLI 122 Query: 205 INGPASLPYDIDLGVFPITDYYYRAADDLVHFTQNNAPPFSDNVLINGTAVNPNTGEGQY 264 + LP + + DY +D + + + + +N + + Sbjct: 123 VEPKNPLPIEKTVT----KDYILMLSDWVSSWANKPGEGGIPGDVFDYYTINAKSFP-ET 177 Query: 265 ANVTLTPGKRHRLRILNTSTENHFQVSLVNHTMTVIAADMVPVN-AMTVDSLFLAVGQRY 323 + + G RLR++ H + H + D P++ + D++ + G+RY Sbjct: 178 QPIRVKKGDVIRLRLIGAGDHVH-AIHTHGHISQIAFKDGFPLDKPIKGDTVLIGPGERY 236 Query: 324 DVVIDASRAPDNYWFNVTFGGQAACGGSLNPHPAAIFHYAGAPGGLP 370 DV+++ P + + G + Y P Sbjct: 237 DVILNMDN-PGLWMIHDHVDTHTTNGDKPDGGIMTTIEYEEVGIDHP 282 Score = 51.4 bits (121), Expect = 1e-06, Method: Composition-based stats. Identities = 19/82 (23%), Positives = 29/82 (35%), Gaps = 20/82 (24%) Query: 481 HPMHLHGHDFLVLGRSPDVPAASQQRFVFDPAVDLARLNGDNPPRRDTTMLPAGGWLLLA 540 H +H HGH + + D P + DT ++ G + Sbjct: 200 HAIHTHGHISQIAFKDGFP--------------------LDKPIKGDTVLIGPGERYDVI 239 Query: 541 FRTDNPGAWLFHCHIAWHVSGG 562 DNPG W+ H H+ H + G Sbjct: 240 LNMDNPGLWMIHDHVDTHTTNG 261 Score = 35.6 bits (80), Expect = 0.061, Method: Composition-based stats. Identities = 27/155 (17%), Positives = 48/155 (30%), Gaps = 30/155 (19%) Query: 451 VSDNIVQVDAVDQWTYWLIENDPEGPFSLPHPMHLHGHDFLVLGRSPDVPAASQQRFVFD 510 + V + + + +LPH +H HG +S VP A+Q Sbjct: 26 AFNGQVPAPLIHVMEGDDVTVNVTNMTTLPHTIHWHGMLQRGTWQSDGVPHATQH----- 80 Query: 511 PAVDLARLNGDNPPRRDTTMLPAGGWLLLAFRTDNPGAWLFHCH--IAWHVSG-GL-SVD 566 + G F+ + G +HCH + HV+ G+ Sbjct: 81 -------------------AIEPGDTFTYKFKAEPAGTMWYHCHVNVNEHVTMRGMWGPL 121 Query: 567 FLERPADLRQRISQEDEDDFNRVCDEWRAYWPTNP 601 +E I + D+ + +W + W P Sbjct: 122 IVE--PKNPLPIEKTVTKDYILMLSDWVSSWANKP 154 >2YAP-A nrPDB Length = 439 Score = 223 bits (569), Expect = 1e-58, Method: Composition-based stats. Identities = 99/506 (19%), Positives = 160/506 (31%), Gaps = 86/506 (16%) Query: 76 STPDTGVTQSYVFNLTE-VDNWMGPDGVVKEKVMLI--NGNIMGPNIVANWGDTVEVTVI 132 S P+ V +S L+ + P + ++ L+ G+ GP + DTV +T+ Sbjct: 3 SFPEPKVVRSQGGLLSLKLSATPTPLAIAGQRATLLTYGGSFPGPTLRVRPRDTVRLTLE 62 Query: 133 NNLVTNGTSIHWHGIHQKDTNLHDGANGVTECPIPPKGGQRTYRWRARQ--YGTSWYHSH 190 N L T++HWHG+ + D IPP G TY + + GT WYH H Sbjct: 63 NRLP-EPTNLHWHGL--PISPKVDDPF----LEIPP-GESWTYEFTVPKELAGTFWYHPH 114 Query: 191 FS----AQYGNGVVGTIQIN---GPASLPYDIDLGVFPITDYYYRAADDLVHFTQNNAPP 243 Q G++G + + + + + + D + H + Sbjct: 115 LHGRVAPQLFAGLLGALVVESSLDAIPELREAEEHLLVLKDLALQGGRPAPHTPMD---- 170 Query: 244 FSDNVLINGTAVNPNTGEGQYANVTLTPGKRHRLRILNTSTENHFQVSLVNHTMTVIAAD 303 +NG + G + RLR+LN S +++++L +H + +IAAD Sbjct: 171 -----WMNGKEGDLVLVNGALRPTLVAQKATLRLRLLNASNARYYRLALQDHPLYLIAAD 225 Query: 304 MVPV-NAMTVDSLFLAVGQRYDVVIDASRAPDNYWFNV-TFGGQAACGGSLNPHPAAIFH 361 + + V L LA G+R +V++ + + + A + A+ Sbjct: 226 GGFLEEPLEVSELLLAPGERAEVLVRLRK-EGRFLLQALPYDRGAMGMMDMGGMAHAMPQ 284 Query: 362 YAGAPGGLPTDEGTPPVDHQCLDTLDVRPVVPRSVPVNSFVKRPDNTLPVALDLTGTPLF 421 P L L + P PV L + D+ F Sbjct: 285 GPSRPETLLYLIAPKNPKPLPL-PKALSPFPTLPAPV------VTRRLVLTEDMMAARFF 337 Query: 422 VWKVNGSDINVDWGKPIIDYILTGNTSYPVSDNIVQVDAVDQWTYWLIENDPEGPFSLPH 481 + VD W +EN + + H Sbjct: 338 INGQVFDHRRVDLK-----------------------GQAQTVEVWEVENQGD----MDH 370 Query: 482 PMHLHGHDFLVLGRSPDVPAASQQRFVFDPAVDLARLNGDNPPRRDTTMLPAGGWLLLAF 541 P HLH H F VL +D L AG L Sbjct: 371 PFHLHVHPFQVLSVGGRPFPYRA--------------------WKDVVNLKAGEVARLLV 410 Query: 542 RTDNPGAWLFHCHIAWHVSGGLSVDF 567 G +FHCHI H G+ Sbjct: 411 PLREKGRTVFHCHIVEHEDRGMMGVL 436 >3ZX1-A nrPDB Length = 481 Score = 219 bits (557), Expect = 3e-57, Method: Composition-based stats. Identities = 98/484 (20%), Positives = 157/484 (32%), Gaps = 69/484 (14%) Query: 88 FNLTEVDNWMGPDGVVKEKVMLINGNIMGPNIVANWGDTVEVTVINNLVTNGTSIHWHGI 147 L +N + K NG + P I GD +E+ V N L T+IHWHG+ Sbjct: 53 ATLEIKENHIELIKGKKTLFYTYNGLVPAPKIEVFEGDKLEILVKNKL-KEATTIHWHGV 111 Query: 148 HQKDTNLHDGANGVTECPIPPKGGQRTYRWRARQ--YGTSWYHSH----FSAQYGNGVVG 201 DG+ PI G +R YR+ Q GT WYH H S Q G+ G Sbjct: 112 PVPPDQ--DGSPH---DPIL-AGEERIYRFEIPQDSAGTYWYHPHPHYTASKQVFMGLAG 165 Query: 202 TIQINGPASLPYDIDLGVFPITDYYYRAADDLVHFTQNNAPPFSDNVLINGTAVNPNTGE 261 I + I+D D+ NN N +NG Sbjct: 166 AFVIKAKKDALSHLKEKDLMISDLR---LDENAQIPNNNL-----NDWLNGREGEFVLIN 217 Query: 262 GQYANVTLTPGKRHRLRILNTSTENHFQVSLVNHTMTVIAADMVPVNA-MTVDSLFLAVG 320 GQ+ + R+RI N + + + + ++ D + + + LFL+ Sbjct: 218 GQFKP-KIKLATNERIRIYNATAARYLNLRIQGAKFILVGTDGGLIEKTIYKEELFLSPA 276 Query: 321 QRYDVVIDASRAPDNYWFNVTFGGQAACGGSLNPHPAAIFHYAGAPGGLPTDEGTPPVDH 380 R +V+IDA + N F + + P +F A L + P Sbjct: 277 SRVEVLIDAPKD-GN--FKLESAYYDRDKMMVKEEPNTLF---LANINLKKENVELPK-- 328 Query: 381 QCLDTLDVRPVVPRSVPVNSFVKRPDNTLPVALDLTGTPLFVWKVNGSDINVDWGKPIID 440 +++ P P + + ++ D + K G K + Sbjct: 329 ------NLKIFKPSEEP------KEFKEIIMSEDHMQMHGMMGKSEGE------LKIALA 370 Query: 441 YILTGNTSYPVSDNIVQVDAVDQWTYWLIENDPEGPFSLPHPMHLHGHDFLVLGRSPDVP 500 + N I + W++ N + HP H+HG F ++ + Sbjct: 371 SMFLINRKSYDLKRIDLSSKLGVVEDWIVINKSH----MDHPFHIHGTQFELISSKLNGK 426 Query: 501 AASQQRFVFDPAVDLARLNGDNPPRRDTTMLPAGGWLLLAFRTDNPGAWLFHCHIAWHVS 560 + RDT + L L + D G ++HCHI H Sbjct: 427 VQKAEFRA----------------LRDTINVRPNEELRLRMKQDFKGLRMYHCHILEHED 470 Query: 561 GGLS 564 G+ Sbjct: 471 LGMM 474 >6IQY-A nrPDB Length = 538 Score = 144 bits (364), Expect = 7e-35, Method: Composition-based stats. Identities = 98/528 (18%), Positives = 157/528 (29%), Gaps = 97/528 (18%) Query: 86 YVFNLTEVDNWMGPDGVVKEKVMLINGNIMGPNIVANWGDTVEVTVINNLVTNGTSIHWH 145 Y + + + PD + ++ +G GP G V INN S+H H Sbjct: 43 YEVEIKPFTHQVYPD-LGSADLVGYDGMSPGPTFQVPRGVETVVRFINNAEA-PNSVHLH 100 Query: 146 GIHQKDTNLHDGANGVTECPIPPKGGQRTYRWRARQYG-TSWYHSH----FSAQYGNGVV 200 G + DG I G + Y + RQ T WYH H + G Sbjct: 101 GSFSR--AAFDGWA----EDITEPGSFKDYYYPNRQSARTLWYHDHAMHITAENAYRGQA 154 Query: 201 GTIQINGPA------SLPYDIDLGVFPITDYYYRAADDLVHFTQNNAPPFSDNVLINGTA 254 G + PA Y +T Y A +LV + D + +NG Sbjct: 155 GLYMLTDPAEDALNLPSGYGEFDIPMILTSKQYTANGNLVTTNGELNSFWGDVIHVNGQP 214 Query: 255 VNPNTGEGQYANVTLTPGKRHRLRILNTSTENHFQV------SLVNH-TMTVIAADMVPV 307 + P K +R R L+ + F + ++ VIA+D + Sbjct: 215 WPFK---------NVEPRK-YRFRFLDAAVSRSFGLYFADTDAIDTRLPFKVIASDSGLL 264 Query: 308 N-AMTVDSLFLAVGQRYDVVIDASRAPDNYWFNVTFGGQAACGGSLNP--HPAAIFHYAG 364 L++++ +RY+VV D S GG G+ + + + Sbjct: 265 EHPADTSLLYISMAERYEVVFDFSDYAGKTIELRNLGGSIGGIGTDTDYDNTDKVMRFVV 324 Query: 365 APGGLPTDEGTPPVDHQCLDTLDVRPVVPRSVPVNSFVKRPDNTLPVALDLTGTPLFVWK 424 A D P + + VP P + TG W Sbjct: 325 ADDTTQPDTSVVPANLRD---------VPFPSPTTNTP------RQFRFGRTG---PTWT 366 Query: 425 VNGSDINVDWGKPIIDYILTGNTSYPVSDNIVQVDAVDQWTYWLIENDPEGPFSLPHPMH 484 +NG V + ++ V W + N G HP+H Sbjct: 367 INGVAF------------------ADVQNRLLANVPVGTVERWELINAGNGW---THPIH 405 Query: 485 LHGHDFLVLGRSPDVPAASQQRFVFDPAVDLARLNGDNPPRRDTTMLPAGGWLLL-AFRT 543 +H DF V+ R+ A + + +D L +++ A Sbjct: 406 IHLVDFKVISRTSGNNARTVMPYE--------------SGLKDVVWLGRRETVVVEAHYA 451 Query: 544 DNPGAWLFHCHIAWHVSGGLSVDF-LERPADL---RQRISQEDEDDFN 587 PG ++FHCH H F D E+ + Sbjct: 452 PFPGVYMFHCHNLIHEDHDQMAAFNATVLPDYGYNATVFVDPMEELWQ 499 >3GDC-A nrPDB Length = 288 Score = 140 bits (352), Expect = 2e-33, Method: Composition-based stats. Identities = 47/235 (20%), Positives = 80/235 (34%), Gaps = 27/235 (11%) Query: 111 NGNIMGPNIVANWGDTVEVTVINNLVTNGTSIHWHGIHQKDTNLHDGANGVTECPIPPKG 170 NG I GP + A GD + + N + +IH+HG+H+ DG G+ I P G Sbjct: 60 NGRIPGPTLWAREGDALRIH-FTNAGAHPHTIHFHGVHRAT---MDGTPGIGAGSIAP-G 114 Query: 171 GQRTYRWRARQYGTSWYHSH---FSAQYGNGVVGTIQINGPASLPYDIDLGVFPITDYYY 227 TY + A +GT YH H + G+ G + P D V + Y Sbjct: 115 QSFTYEFDATPFGTHLYHCHQSPLAPHIAKGLYGGFIVEPKEGRPPADDEMVMVMNGYNT 174 Query: 228 RAADDLVHFTQNNAPPFSDNVLINGTAVNPNTGEGQYANVTLTPGKRHRLRILNT-STEN 286 DD ++ N P V + + R+ ++N + Sbjct: 175 DGGDDNEFYSVNGLPFHF-----------------MDFPVKVKQHELVRIHLINVLEYDP 217 Query: 287 HFQVSLVNHTMTVIAADMVPVNAMTVDSLFLAVGQRYDVVIDASRAPDNYWFNVT 341 + + + + D++ GQR + + P + F+ Sbjct: 218 INSFHIHGNFFHYYPTGTMLTPSEYTDTISQVQGQRGILELRFP-YPGKFMFHAH 271 Score = 32.9 bits (73), Expect = 0.45, Method: Composition-based stats. Identities = 27/130 (20%), Positives = 40/130 (30%), Gaps = 35/130 (26%) Query: 460 AVDQWTYWLIENDP-----EGPFSLPHPMHLHGHDFLVLGRSPDVPAASQQRFVFDPAVD 514 + T W E D + PH +H HG + +P + A S Sbjct: 62 RIPGPTLWAREGDALRIHFTNAGAHPHTIHFHGVHRATMDGTPGIGAGS----------- 110 Query: 515 LARLNGDNPPRRDTTMLPAGGWLLLAFRTDNPGAWLFHCH---IAWHVSGGLSVDFLERP 571 + G F G L+HCH +A H++ GL F+ P Sbjct: 111 ----------------IAPGQSFTYEFDATPFGTHLYHCHQSPLAPHIAKGLYGGFIVEP 154 Query: 572 ADLRQRISQE 581 + R E Sbjct: 155 KEGRPPADDE 164 Score = 31.7 bits (70), Expect = 0.90, Method: Composition-based stats. Identities = 24/126 (19%), Positives = 42/126 (33%), Gaps = 12/126 (9%) Query: 89 NLTEVDNWMGPDGVVKEKVMLINGN------IMGPNIVANWGDTVEVTVINNLVTNG-TS 141 + V N DG + +NG + + V + +IN L + S Sbjct: 164 EMVMVMNGYNTDGGDDNEFYSVNGLPFHFMDFP---VKVKQHELVRIHLINVLEYDPINS 220 Query: 142 IHWHG--IHQKDTNLHDGANGVTECPIPPKGGQRTYRWRARQYGTSWYHSHFSAQYGNGV 199 H HG H T + T+ +G + R G +H+H + G Sbjct: 221 FHIHGNFFHYYPTGTMLTPSEYTDTISQVQGQRGILELRFPYPGKFMFHAHKTEFAELGW 280 Query: 200 VGTIQI 205 +G ++ Sbjct: 281 MGFFEV 286 Score = 31.3 bits (69), Expect = 1.3, Method: Composition-based stats. Identities = 34/210 (16%), Positives = 53/210 (25%), Gaps = 38/210 (18%) Query: 364 GAPGGLPTDEGTPPVDHQCLDTLDVR----PVVPRSVPV--NSFVKRPDNTLPVALDLTG 417 GA P T D T P+ P F+ P P A D Sbjct: 107 GAGSIAPGQSFTYEFDATPFGTHLYHCHQSPLAPHIAKGLYGGFIVEPKEGRPPADDEMV 166 Query: 418 TPLFVWKVNGSDINVDWGKPIIDYILTGNTSYPVSDNIVQVDAVDQWTYWLIENDPEGPF 477 + + +G D N + + + + Q + V ++E DP Sbjct: 167 MVMNGYNTDGGDDNEFYSVNGLPFHF-----MDFPVKVKQHELVRIHLINVLEYDPINS- 220 Query: 478 SLPHPMHLHGHDFLVLGRSPDVPAASQQRFVFDPAVDLARLNGDNPPRRDTTMLPAGGWL 537 H+HG+ F + + + L P Sbjct: 221 -----FHIHGNFFHYYPTGTMLTPSEYTDTISQVQGQRGILELRFPY------------- 262 Query: 538 LLAFRTDNPGAWLFHCHIAWHVSGGLSVDF 567 PG ++FH H G F Sbjct: 263 --------PGKFMFHAHKTEFAELGWMGFF 284 >3GYR-A nrPDB Length = 612 Score = 138 bits (348), Expect = 5e-33, Method: Composition-based stats. Identities = 105/591 (17%), Positives = 165/591 (27%), Gaps = 127/591 (21%) Query: 82 VTQSYVFNLTEVDNWMGPDGVVKEKVMLINGNIMGPNIVANWGDTVEVTVINNLVTNG-- 139 VT+ L + P + + +G + GP I G V + N + Sbjct: 31 VTRETEIALRPTWVRLHPQ-LPPTLMWGYDGQVPGPTIEVRRGQRVRIAWTNRIPKGSEY 89 Query: 140 --TSI------------------------------------HWHGIHQKDTN--LHDGAN 159 TS+ H HG N D A Sbjct: 90 PVTSVEVPLGPPGTPAPNTEPGRGGVEPNKDVAALPAWSVTHLHGAQTGGGNDGWADNAV 149 Query: 160 GVTECPIPPKGGQRTYRWRARQYGT-SWYHSHFSA----QYGNGVVGTIQINGPA----S 210 G G + + T WYH H G+ GT + Sbjct: 150 GF--------GDAQLSEYPNDHQATQWWYHDHAMNITRWNVMAGLYGTYLVRDDEEDALG 201 Query: 211 LPYDIDLGVFPITDYYYRAADD------LVHFTQNNAPPFSDNVLINGTAVN-PNTGEGQ 263 LP I D +D L+H T + G V+ P G Sbjct: 202 LPSGDREIPLLIADRNLDTDEDGRLNGRLLHKTVIVQQSNPET----GKPVSIPFFGPYT 257 Query: 264 YANVTLTP-----GKRHRLRILNTSTENHFQVSLVNHT-------MTVIAADMVPV-NAM 310 N + P +RLR++N S + + L++ + I +D + + Sbjct: 258 TVNGRIWPYADVDDGWYRLRLVNASNARIYNLVLIDEDDRPVPGVVHQIGSDGGLLPRPV 317 Query: 311 TVD------SLFLAVGQRYDVVIDASRAPDNYWFNVTFGGQAACGGSLNPHPAAIFHYAG 364 VD L A +R+D+++D V G A G P P Y Sbjct: 318 PVDFDDTLPVLSAAPAERFDLLVDFRALGGRRLRLVDKGPGAPAG---TPDPLGGVRYP- 373 Query: 365 APGGLPTDEGTPPVDHQCLDTLDVRPVVPRSV-----PVNSFVKRPDNTLPVALDLTGTP 419 + V C + P V R P +G Sbjct: 374 -------EVMEFRVRETCEEDSFALPEVLSGSFRRMSHDIPHGHRLIVLTPPGTKGSGGH 426 Query: 420 LFVWKVNGSDINVDWGKPIIDYILTGN----------TSYPVSDNIVQVDAVDQWTYWLI 469 +W++ + D P I T+ +D + W Sbjct: 427 PEIWEMAEVEDPADVQVPAEGVIQVTGADGRTKTYRRTARTFNDGLGFTIGEGTHEQWTF 486 Query: 470 ENDPEGPFSLPHPMHLHGHDFLVLGRSPDVPAA------SQQRFVFDPAVDLARLNGDNP 523 N + HPMH+H DF VLGR + + V L + Sbjct: 487 LNLS----PILHPMHIHLADFQVLGRDAYDASGFDLALGGTRTPVRLDPDTPVPLAPNEL 542 Query: 524 PRRDTTMLPAGGWLLLAFRTDNP-GAWLFHCHIAWHVSGGLSVDFLERPAD 573 +D +P L + + D G +++HCH+ H G+ F+ P + Sbjct: 543 GHKDVFQVPGPQGLRVMGKFDGAYGRFMYHCHLLEHEDMGMMRPFVVMPPE 593 Score = 37.9 bits (86), Expect = 0.014, Method: Composition-based stats. Identities = 11/48 (22%), Positives = 20/48 (41%), Gaps = 1/48 (2%) Query: 167 PPKGGQRTYRWRARQYGTSWYHSHFSAQYGNGVVGTIQINGPASLPYD 214 P+G + ++ YG YH H G++ + P +L +D Sbjct: 552 GPQGLRVMGKFD-GAYGRFMYHCHLLEHEDMGMMRPFVVMPPEALKFD 598 >2UXV-A nrPDB Length = 451 Score = 134 bits (336), Expect = 1e-31, Method: Composition-based stats. Identities = 89/453 (19%), Positives = 144/453 (31%), Gaps = 93/453 (20%) Query: 103 VKEKVMLINGNIMGPNIVANWGDTVEVTVINNLVTNGTSIHWHGIHQKDTNLHDGANGVT 162 + V ING +GP I GD V++ N L T S+ G+ Q L G + Sbjct: 36 TRASVWGINGRYLGPTIRVWKGDDVKLIYSNRL-TENVSMTVAGL-QVPGPLMGGPARM- 92 Query: 163 ECPIPPKGGQRTYRWRARQ-YGTSWYHSHF----SAQYGNGVVGTIQING------PASL 211 + P RQ T WYH++ + Q NG+ G + P Sbjct: 93 ---MSPNAD-WAPVLPIRQNAATLWYHANTPNRTAQQVYNGLAGMWLVEDEVSKSLPIPN 148 Query: 212 PYDIDLGVFPITDYYYRAADDLVHFTQNNAPPFSDNVLINGTAVNPNTGEGQYANVTLTP 271 Y +D I D + + D +L+NG Q V ++ Sbjct: 149 HYGVDDFPVIIQDKRLDNFGTPEYNEPGSGGFVGDTLLVNGV---------QSPYVEVSR 199 Query: 272 GKRHRLRILNTSTENHFQVSL-VNHTMTVIAAD-MVPVNAMTVDSLFLAVGQRYDVVIDA 329 G RLR+LN S +Q+ + + VI+ D ++V L LA G+R ++++D Sbjct: 200 G-WVRLRLLNASNSRRYQLQMNDGRPLHVISGDQGFLPAPVSVKQLSLAPGERREILVDM 258 Query: 330 SRAPDNYWFNVTFGGQAACGGSLNPHPAAIFHYAGAPGGLPTDEGTPPVDHQCLDTLDVR 389 S CG + + + + + T T D Sbjct: 259 SNG---------DEVSITCGEAASIVDRIRGFFEPSSILVSTLVLTLRPTGLLPLVTDSL 309 Query: 390 PVVPRSVPVNSFVKRPDNTLPVAL-DLTGTPLFVWKVNGSDINVDWGKPIIDYILTGNTS 448 P+ R +P P + ++L D G +W VN D+ G Sbjct: 310 PM--RLLPTEIMAGSPIRSRDISLGDDPGINGQLWDVNRIDVTAQQG------------- 354 Query: 449 YPVSDNIVQVDAVDQWTYWLIENDPEGPFSLPHPMHLHGHDFLVLGRSPDVPAASQQRFV 508 W W + D P H+ G F + + +P Sbjct: 355 --------------TWERWTVRADE------PQAFHIEGVMFQIRNVNGAMP-------- 386 Query: 509 FDPAVDLARLNGDNPPRRDTTMLPAGGWLLLAF 541 ++ +DT + LL+ F Sbjct: 387 ----------FPEDRGWKDTVWVDGQVELLVYF 409 >5OCB-A nrPDB Length = 468 Score = 86.8 bits (213), Expect = 3e-17, Method: Composition-based stats. Identities = 52/269 (19%), Positives = 82/269 (30%), Gaps = 26/269 (9%) Query: 109 LINGNIMGPNIVANWGDTVEVTVINNLVTN-GTSIHWHGIHQKDTNLHDGANGVTECPIP 167 G + G I GDTVE + N+ + +I+ HG+ G G Sbjct: 62 TFGGTVPGSFIRVRQGDTVEFHLKNHPSSKMPHNINLHGVT--------GPGGGAASSFT 113 Query: 168 PKGGQRTYRWRARQYGTSWYHSHFSA---QYGNGVVGTIQINGPASLPYDIDLGVFPITD 224 G + + ++A G YH + NG+ G I + P LP D Sbjct: 114 APGHESQFTFKALNEGIYVYHCATAPVGMHIANGMYGLILVEPPEGLPKVDHEYYVMQGD 173 Query: 225 YY----YRAADDLVHFTQNNAPPFSDNVLINGTAVNPNTGEGQYANVTLTPGKRHRLRIL 280 +Y YR + VL NG + +A V G+ R+ + Sbjct: 174 FYTAGKYREKGLQPFDMEKAIDERPSYVLFNGAEGALTGDKALHAKV----GETVRIFVG 229 Query: 281 NTSTENHFQVSLVNHTMTVIAADMVPVNAMTVDSLFLAVGQRYDVVIDASRAPDNYWFNV 340 N ++ + + V + + VV +R P +Y Sbjct: 230 NGGPNLVSSFHVIGAIFDQVRYEGGTNVQKNVQTTLI-PAGGAAVVKFTARVPGSYVLVD 288 Query: 341 TFGGQAACGGSLNPHPAAIFHYAGAPGGL 369 +A N AI GA L Sbjct: 289 HSIFRAF-----NKGAMAILKIDGAENKL 312 Score = 31.7 bits (70), Expect = 1.0, Method: Composition-based stats. Identities = 22/101 (21%), Positives = 42/101 (41%), Gaps = 4/101 (3%) Query: 460 AVDQWTYWLIENDPEGPFSLPHPMHLH-GHDFLVLGRSPDVPAASQQRFVFDPAVDLARL 518 A+D+ +++ N EG + +H G + + P V D R Sbjct: 193 AIDERPSYVLFNGAEGALTGDKALHAKVGETVRIFVGNGG-PNLVSSFHVIGAIFDQVRY 251 Query: 519 NGDNPPRRD--TTMLPAGGWLLLAFRTDNPGAWLFHCHIAW 557 G +++ TT++PAGG ++ F PG+++ H + Sbjct: 252 EGGTNVQKNVQTTLIPAGGAAVVKFTARVPGSYVLVDHSIF 292 >3X1F-A nrPDB Length = 352 Score = 81.4 bits (199), Expect = 1e-15, Method: Composition-based stats. Identities = 52/251 (20%), Positives = 80/251 (31%), Gaps = 16/251 (6%) Query: 106 KVMLINGNIMGPNIVANWGDTVEVTVINNLVTNGTSIHWHGIHQKDTNLHDGANGVTECP 165 K NG GP +V N GDT+ T+ N S+ +H +H + Sbjct: 90 KAWTFNGQAPGPLVVVNEGDTIHFTLKNMDPVVPHSMDFHAVHASPSKDFIDV------- 142 Query: 166 IPPKGGQRTYRWRARQYGTSWYHSHFSA---QYGNGVVGTIQINGPASLPYDIDLG---V 219 +P K G TY A + G YH NG+ G I + P D ++ V Sbjct: 143 MPNKSGTFTY--PANKPGVFMYHCGTKPVLQHIANGMHGVIIVKPKNGYPTDKEVDREYV 200 Query: 220 FPITDYY-YRAADDLVHFTQNNAPPFSDNVLINGTAVNPNTGEGQYANVTLTPGKRHRLR 278 ++Y Y +D + + S + N +T + + G++ RL Sbjct: 201 LIQNEWYKYNDMNDFQNGVPSYVVFSSKALKPGDPNTNGDTFTLKEKPLLAKVGEKIRLY 260 Query: 279 ILNTSTENHFQVSLVNHTMTVIAADMVPVNAMTVDSLFLAVGQRYDVVIDASRAPDNYWF 338 I N +V + D P N + + VV P Y Sbjct: 261 INNVGPNEVSSFHVVGTVFDDVYLDGNPNNHLQGMQTVMLPASGGAVVEFTVTRPGTYPI 320 Query: 339 NVTFGGQAACG 349 A G Sbjct: 321 VTMQFNHAQKG 331 Score = 32.9 bits (73), Expect = 0.42, Method: Composition-based stats. Identities = 14/83 (16%), Positives = 35/83 (42%), Gaps = 4/83 (4%) Query: 523 PPRRDTTMLPAGGWLLLAFRTDNPGAWLFHCH---IAWHVSGGLSVDFLERPADLRQRIS 579 P +D + + + PG +++HC + H++ G+ + +P + Sbjct: 134 SPSKDFIDVMPNKSGTFTYPANKPGVFMYHCGTKPVLQHIANGMHGVIIVKPKN-GYPTD 192 Query: 580 QEDEDDFNRVCDEWRAYWPTNPY 602 +E + ++ + +EW Y N + Sbjct: 193 KEVDREYVLIQNEWYKYNDMNDF 215 >4KNS-A nrPDB Length = 285 Score = 81.0 bits (198), Expect = 1e-15, Method: Composition-based stats. Identities = 38/207 (18%), Positives = 70/207 (33%), Gaps = 19/207 (9%) Query: 84 QSYVFNLTEVDNWMGPDGVVKE-KVMLINGNIMGPNIVANWGDTVEVTVINNLVT-NGTS 141 ++ L V+ + D + +G + GP + GDTVE T+IN+ + N S Sbjct: 1 KTVQVTLHAVETDVAYDNKGSTYRAWTFDGKVPGPVVRVTEGDTVEFTLINDKNSKNSHS 60 Query: 142 IHWHGIHQKDTNLHDGANGVTECPIPPKGGQRTYRWRARQYGTSWYHSHFSA---QYGNG 198 + +H + V + G + Y + A G +YH G Sbjct: 61 MDFHAAR---------LDVVEDFESIKPGETKKYTFTADNPGVFFYHCGSDPMIQHIARG 111 Query: 199 VVGTIQINGP--ASLPYDIDLGVFPITDYYYRAADDLVHFTQNNAPPFSDNVLINGTAVN 256 + G I ++ +LP V ++Y D + + + V+ Sbjct: 112 MYGVIIVDPKDANALPKADREYVLIQAEHYENPDDKTAMMQNKWSNVVFNGGVFKYDPVH 171 Query: 257 PNTGEGQYANVTLTPGKRHRLRILNTS 283 + PG+R R+ +N Sbjct: 172 DSEATSWLQA---KPGERVRIYFVNAG 195 Score = 39.4 bits (90), Expect = 0.005, Method: Composition-based stats. Identities = 13/52 (25%), Positives = 20/52 (38%), Gaps = 3/52 (5%) Query: 527 DTTMLPAGGWLLLAFRTDNPGAWLFHCHIAW---HVSGGLSVDFLERPADLR 575 D + G F DNPG + +HC H++ G+ + P D Sbjct: 73 DFESIKPGETKKYTFTADNPGVFFYHCGSDPMIQHIARGMYGVIIVDPKDAN 124 >3WIA-A nrPDB Length = 287 Score = 80.6 bits (197), Expect = 2e-15, Method: Composition-based stats. Identities = 52/251 (20%), Positives = 80/251 (31%), Gaps = 16/251 (6%) Query: 106 KVMLINGNIMGPNIVANWGDTVEVTVINNLVTNGTSIHWHGIHQKDTNLHDGANGVTECP 165 K NG GP +V N GDT+ T+ N S+ +H +H + Sbjct: 25 KAWTFNGQAPGPLVVVNEGDTIHFTLKNMDPVVPHSMDFHAVHASPSKDFIDV------- 77 Query: 166 IPPKGGQRTYRWRARQYGTSWYHSHFSA---QYGNGVVGTIQINGPASLPYDIDLG---V 219 +P K G TY A + G YH NG+ G I + P D ++ V Sbjct: 78 MPNKSGTFTY--PANKPGVFMYHCGTKPVLQHIANGMHGVIIVKPKNGYPTDKEVDREYV 135 Query: 220 FPITDYY-YRAADDLVHFTQNNAPPFSDNVLINGTAVNPNTGEGQYANVTLTPGKRHRLR 278 ++Y Y +D + + S + N +T + + G++ RL Sbjct: 136 LIQNEWYKYNDMNDFQNGVPSYVVFSSKALKPGDPNTNGDTFTLKEKPLLAKVGEKIRLY 195 Query: 279 ILNTSTENHFQVSLVNHTMTVIAADMVPVNAMTVDSLFLAVGQRYDVVIDASRAPDNYWF 338 I N +V + D P N + + VV P Y Sbjct: 196 INNVGPNEVSSFHVVGTVFDDVYLDGNPNNHLQGMQTVMLPASGGAVVEFTVTRPGTYPI 255 Query: 339 NVTFGGQAACG 349 A G Sbjct: 256 VTHQFNHAQKG 266 Score = 32.5 bits (72), Expect = 0.64, Method: Composition-based stats. Identities = 14/83 (16%), Positives = 35/83 (42%), Gaps = 4/83 (4%) Query: 523 PPRRDTTMLPAGGWLLLAFRTDNPGAWLFHCH---IAWHVSGGLSVDFLERPADLRQRIS 579 P +D + + + PG +++HC + H++ G+ + +P + Sbjct: 69 SPSKDFIDVMPNKSGTFTYPANKPGVFMYHCGTKPVLQHIANGMHGVIIVKPKN-GYPTD 127 Query: 580 QEDEDDFNRVCDEWRAYWPTNPY 602 +E + ++ + +EW Y N + Sbjct: 128 KEVDREYVLIQNEWYKYNDMNDF 150 >5TB7-A nrPDB Length = 337 Score = 79.9 bits (195), Expect = 3e-15, Method: Composition-based stats. Identities = 52/271 (19%), Positives = 86/271 (31%), Gaps = 21/271 (7%) Query: 90 LTEVDNWMGPDGVVKEKVMLINGNIMGPNIVANWGDTVEVTVINNLVTNGTSIHWHGIHQ 149 + V+ M D V+ + +G++ G I GDTVEV NN + T H H Sbjct: 43 METVEKTMKMDDGVEYRYWTFDGDVPGRMIRVREGDTVEVEFSNN--PSSTVPHNVDFHA 100 Query: 150 KDTNLHDGANGVTECPIPPKGGQRTYRWRARQYGTSWYHSHFSA---QYGNGVVGTIQIN 206 A T G T+ ++A Q G YH + NG+ G I + Sbjct: 101 ATGQGGGAAATFTA-----PGRTSTFSFKALQPGLYIYHCAVAPVGMHIANGMYGLILVE 155 Query: 207 GPASLPYDIDLGVFPITDYYYRAADD----LVHFTQNNAPPFSDNVLINGTAVNPNTGEG 262 LP D+Y + + V+ NG + G Sbjct: 156 PKEGLPKVDKEFYIVQGDFYTKGKKGAQGLQPFDMDKAVAEQPEYVVFNG---HVGAIAG 212 Query: 263 QYANVTLTPGKRHRLRILNTSTENHFQVSLVNHTMTVIAADMVPVNAMTVDSLFLAVGQR 322 A + G+ R+ + N ++ + + + V S + G Sbjct: 213 DNA-LKAKAGETVRMYVGNGGPNLVSSFHVIGEIFDKVYVEGGKLINENVQSTIVPAGG- 270 Query: 323 YDVVIDAS-RAPDNYWFNVTFGGQAACGGSL 352 +++ P NY +A G+L Sbjct: 271 -SAIVEFKVDIPGNYTLVDHSIFRAFNKGAL 300 Score = 29.0 bits (63), Expect = 5.9, Method: Composition-based stats. Identities = 10/43 (23%), Positives = 21/43 (48%), Gaps = 4/43 (9%) Query: 531 LPAGGWLLLAFRTDNPGAWLFHCHIAW---HVSGGL-SVDFLE 569 G +F+ PG +++HC +A H++ G+ + +E Sbjct: 113 TAPGRTSTFSFKALQPGLYIYHCAVAPVGMHIANGMYGLILVE 155 >2ZOO-A nrPDB Length = 442 Score = 76.8 bits (187), Expect = 3e-14, Method: Composition-based stats. Identities = 38/219 (17%), Positives = 65/219 (29%), Gaps = 20/219 (9%) Query: 110 INGNIMGPNIVANWGDTVEVTVINNLVTN-GTSIHWHGIHQKDTNLHDGANGVTECPIPP 168 + G I GD +E + N+ + +I H + G G E Sbjct: 53 FGETVPGSFIRVREGDEIEFNLSNHPSSKMPHNIDLHAVT--------GPGGGAESSFTA 104 Query: 169 KGGQRTYRWRARQYGTSWYHSHFSA---QYGNGVVGTIQINGPASLPYDIDLGVFPITDY 225 G T+ ++A G YH + NG+ G I + L D+ Sbjct: 105 PGHTSTFNFKALNPGLYIYHCATAPVGMHIANGMYGLILVEPKEGLAPVDREYYLVQGDF 164 Query: 226 YYRA----ADDLVHFTQNNAPPFSDNVLINGTAVNPNTGEGQYANVTLTPGKRHRLRILN 281 Y + A +D V+ NG+ + A V G+ RL I N Sbjct: 165 YTKGEFGEAGLQPFDMAKAIDEDADYVVFNGSVGSTTDENSLTAKV----GETVRLYIGN 220 Query: 282 TSTENHFQVSLVNHTMTVIAADMVPVNAMTVDSLFLAVG 320 ++ + + + V + + G Sbjct: 221 GGPNLVSSFHVIGEIFDTVYVEGGSLKNHNVQTTLIPAG 259 Score = 34.4 bits (77), Expect = 0.15, Method: Composition-based stats. Identities = 21/110 (19%), Positives = 41/110 (37%), Gaps = 7/110 (6%) Query: 108 MLINGNIMGPN----IVANWGDTVEVTVINNLVTNGTSIHWHGIHQKDTNLHDGA--NGV 161 ++ NG++ + A G+TV + + N +S H G + G+ N Sbjct: 191 VVFNGSVGSTTDENSLTAKVGETVRLYIGNGGPNLVSSFHVIGEIFDTVYVEGGSLKNHN 250 Query: 162 TECPIPPKGGQRTYRWRARQYGTSWYHSH-FSAQYGNGVVGTIQINGPAS 210 + + P GG ++ GT H + G + +++ GP Sbjct: 251 VQTTLIPAGGAAIVEFKVEVPGTFILVDHSIFRAFNKGALAMLKVEGPDD 300 Score = 31.3 bits (69), Expect = 1.2, Method: Composition-based stats. Identities = 11/47 (23%), Positives = 23/47 (48%), Gaps = 4/47 (8%) Query: 527 DTTMLPAGGWLLLAFRTDNPGAWLFHCHIAW---HVSGGL-SVDFLE 569 +++ G F+ NPG +++HC A H++ G+ + +E Sbjct: 99 ESSFTAPGHTSTFNFKALNPGLYIYHCATAPVGMHIANGMYGLILVE 145 >6HBE-A nrPDB Length = 451 Score = 67.6 bits (163), Expect = 2e-11, Method: Composition-based stats. Identities = 77/428 (17%), Positives = 125/428 (29%), Gaps = 49/428 (11%) Query: 81 GVTQSYVFNLTEVDNWMGPDGVVKEKVMLINGNIMGPNIVANWGDTVEVTVINNLVTNGT 140 GV F L + D V + N GP +V GDTV +T+ N + N T Sbjct: 17 GVAAERHFTLEARSSIFEVDQGVYLRGFSFNDMSPGPMLVVEEGDTVHITLRN--LDNVT 74 Query: 141 SIHWHGIHQKDTNLHDGANGVTECPIPPKGGQRTYRWRARQYGTSWYHS----H-FSAQY 195 HG+ N P G R + + A G YH H A Sbjct: 75 ----HGLSIHAANTQTSRFLGNVQP----GETREFSFTADFPGVFMYHCAPGGHGIMAHT 126 Query: 196 GNGVVGTIQINGPAS------LPYDIDLGVFPITDYYYRAADDLVHFTQNNAPPFSDNVL 249 G G I + L DL ++ I Y + D V+ Sbjct: 127 MGGQFGMIVVEPKEKYRMERELGRGPDLKLYIIQSEAYASGRDFYDGKALY-------VM 179 Query: 250 INGTAVNPNTGEGQYANVTLTPGKRHRLRILNTSTENHFQVSLVNHTMTVIAADMVPVNA 309 NG + + PG R+ LN + +V + P N Sbjct: 180 FNGRNFRYVDEP-----IPVRPGDYLRIYFLNVGPNLTSTLHVVGGIFEYMYYQGNPKN- 233 Query: 310 MTVDSLFLAVGQRYDVVIDASRAP--DNYWFNVTFGGQAACG--GSLNPHPAAIFHYAGA 365 + V + G VI+ P +Y G A G G L A Sbjct: 234 LVVGAQTALAGPSDSWVIEWRVPPVEGDYTLVTHVFGTAIKGALGILRAKKDAPRIPEVR 293 Query: 366 PGGLPTDEGTPPVDHQCLDTLDV----------RPVVPRSVPVNSFVKRPDNTLPVALDL 415 G+P + P + +D + P+ P + + LPV + + Sbjct: 294 AEGVPGVKEIPASAKRVVDPYGLASPGHEHTVRVPLDPALAQPVAVGAKALEPLPVTVQM 353 Query: 416 TGTPLFVWKVN-GSDINVDWGKPIIDYILTGNTSYPVSDNIVQVDAVDQWTYWLIENDPE 474 G + + V++ + +L G + ++ V + + + + Sbjct: 354 VGNSFYPKVLEIPVGTTVEFVNEDVFDLLEGERTGRHDAVVIDVQGPEPFVTPKLGHGER 413 Query: 475 GPFSLPHP 482 + P Sbjct: 414 YRITFTKP 421 Score = 32.9 bits (73), Expect = 0.40, Method: Composition-based stats. Identities = 13/45 (28%), Positives = 20/45 (44%), Gaps = 6/45 (13%) Query: 531 LPAGGWLLLAFRTDNPGAWLFHC----H-IAWHVSGG-LSVDFLE 569 + G +F D PG +++HC H I H GG + +E Sbjct: 93 VQPGETREFSFTADFPGVFMYHCAPGGHGIMAHTMGGQFGMIVVE 137 >2DV6-A nrPDB Length = 447 Score = 62.5 bits (150), Expect = 5e-10, Method: Composition-based stats. Identities = 53/279 (18%), Positives = 92/279 (32%), Gaps = 29/279 (10%) Query: 57 PSNRA-CWSDGFDINTDYEVSTPDTG--VTQSYVFNLTEVDNWMGPDGVVKEKVMLINGN 113 P NRA S G DI D G ++ +L V+ D NG Sbjct: 132 PGNRAEMKSSGADITRDPADLPGPIGPRQAKTVRIDLETVEVKGQLDDNTTYTYWTFNGK 191 Query: 114 IMGPNIVANWGDTVEVTVINNLVTNGTSIHWHGIHQKDTNLHDGANGVTECPIPPKGGQR 173 + GP + GDTVE+ + N + S+ H + GA T+ G + Sbjct: 192 VPGPFLRVRVGDTVELHLKN----HKDSLMVHSVDFHGATGPGGAAAFTQ---TDPGEET 244 Query: 174 TYRWRARQYGTSWYHS---HFSAQYGNGVVGTIQINGPASLPYDIDLGVFPITDYYYR-- 228 ++A G YH NG+ G + + LP +D + + Y Sbjct: 245 VVTFKALIPGIYVYHCATPSVPTHITNGMYGLLLVEPEGGLP-QVDREFYVMQGEIYTVK 303 Query: 229 ---AADDLVHFTQNNAPPFSDNVLINGTAVNPNTGEGQYANVTLTPGKRHRLRILNTSTE 285 + + + + L NG+ + YA+V T +RI Sbjct: 304 SFGTSGEQEMDYEKLINEKPEYFLFNGSVGSLTRSHPLYASVGET------VRIFFGVGG 357 Query: 286 NHFQ--VSLVNHTMTVIAADMVPVNA--MTVDSLFLAVG 320 +F ++ + + V+ + V ++ + G Sbjct: 358 PNFTSSFHVIGEIFDHVYSLGSVVSPPLIGVQTVSVPPG 396 Score = 35.6 bits (80), Expect = 0.068, Method: Composition-based stats. Identities = 27/135 (20%), Positives = 48/135 (35%), Gaps = 22/135 (16%) Query: 74 EVSTPDTGVTQSYVFNLTEVDNWMGPDGVVKEKVMLINGNI---MGPNIVANWGDTVEVT 130 E + P G VF L + + + G+I + P +V + G+TV+V Sbjct: 15 EKTDPTAGAHAPVVFTLRTGIA------EGRMVYIGVGGDIDHKINPTLVVHEGETVQVN 68 Query: 131 VINNLVTNGTSIHWHGIHQKDTNLHDGANGVTECPIPPKGGQRTYRWRARQYGTSWYHSH 190 ++N Q D + A + K T+ + A + G Y+ Sbjct: 69 LVNGEGA-----------QHDVVVDQYAA--RSAIVNGKNASSTFSFVASKVGEFNYYCS 115 Query: 191 FSAQYGNGVVGTIQI 205 + G+ G IQ+ Sbjct: 116 IAGHRQAGMEGNIQV 130 Score = 32.5 bits (72), Expect = 0.50, Method: Composition-based stats. Identities = 24/116 (20%), Positives = 47/116 (40%), Gaps = 12/116 (10%) Query: 104 KEKVMLINGNIMGPN----IVANWGDTVEVTVINNLVTNGTSIH------WHGIHQKDTN 153 K + L NG++ + A+ G+TV + +S H H ++ + Sbjct: 322 KPEYFLFNGSVGSLTRSHPLYASVGETVRIFFGVGGPNFTSSFHVIGEIFDH-VYSLGSV 380 Query: 154 LHDGANGVTECPIPPKGGQRTYRWRARQYGTSWYHSHFSAQYGNGVVGTIQINGPA 209 + GV +PP GG ++ + G H ++ +G+VG + ++GP Sbjct: 381 VSPPLIGVQTVSVPP-GGATIVDFKIDRAGRYILVDHALSRLEHGLVGFLNVDGPK 435 Score = 31.0 bits (68), Expect = 1.5, Method: Composition-based stats. Identities = 10/45 (22%), Positives = 22/45 (48%), Gaps = 4/45 (8%) Query: 529 TMLPAGGWLLLAFRTDNPGAWLFHC---HIAWHVSGGL-SVDFLE 569 T G ++ F+ PG +++HC + H++ G+ + +E Sbjct: 236 TQTDPGEETVVTFKALIPGIYVYHCATPSVPTHITNGMYGLLLVE 280 >4NB7-A nrPDB Length = 343 Score = 62.5 bits (150), Expect = 5e-10, Method: Composition-based stats. Identities = 31/128 (24%), Positives = 49/128 (38%), Gaps = 24/128 (18%) Query: 113 NIMGPNIVANWGDTVEVTVINNLVTNGTSIHWHGIHQKDTNLHDGANGVTECPIPPKGGQ 172 ++ GP I N GDT+ + N + S+H HG+ + + DG + + + P GG Sbjct: 73 SVPGPLIEVNEGDTLHIEFTNTMDVRA-SLHVHGLDYEIS--SDGTA-MNKSDVEP-GGT 127 Query: 173 RTYRWRARQYGT------------SW-YHSHFSAQYG------NGVVGTIQINGPASLPY 213 RTY WR + G W YH H NG+ G + + + Sbjct: 128 RTYTWRTHKPGRRDDGTWRPGSAGYWHYHDHVVGTEHGTGGIRNGLYGPVIVRRKGDVLP 187 Query: 214 DIDLGVFP 221 D + Sbjct: 188 DATHTIVF 195 Score = 51.8 bits (122), Expect = 8e-07, Method: Composition-based stats. Identities = 26/124 (20%), Positives = 39/124 (31%), Gaps = 21/124 (16%) Query: 108 MLINGNIM--GPNIVANWGDTVEVTVINNLVTNGTSIHWHGIHQKDTNLHDGANGVTECP 165 M IN GP+ A GD VE+ +I ++H H D G+ P Sbjct: 198 MTINNRKPHTGPDFEATVGDRVEIVMIT------HGEYYHTFHMHGHRWADNRTGILTGP 251 Query: 166 ----------IPPKGGQRTYRWRARQ---YGTSWYHSHFSAQYGNGVVGTIQINGPASLP 212 I ++ A + G YH H + G+VG + P Sbjct: 252 DDPSRVIDNKITGPADSFGFQIIAGEGVGAGAWMYHCHVQSHSDMGMVGLFLVKKPDGTI 311 Query: 213 YDID 216 + Sbjct: 312 PGYE 315 Score = 46.4 bits (108), Expect = 4e-05, Method: Composition-based stats. Identities = 30/150 (20%), Positives = 51/150 (34%), Gaps = 28/150 (18%) Query: 428 SDINVDWGKPIIDYILTGNTSYPVSDNIVQVDAVDQWTYWLIENDPEGPFSLPHPMHLHG 487 D+ D I+ +T N P + + D+ +I + H H+HG Sbjct: 183 GDVLPDATHTIVFNDMTINNRKPHTGPDFEATVGDRVEIVMITHGEYY-----HTFHMHG 237 Query: 488 HDFLVLGRSPDVPAASQQRFVFDPAVDLARLNGDNPPR----RDTTMLPAGGWLLLAFRT 543 H + D+P R + T + G+ ++A Sbjct: 238 HRWA-------------------DNRTGILTGPDDPSRVIDNKITGPADSFGFQIIAGEG 278 Query: 544 DNPGAWLFHCHIAWHVSGGLSVDFLERPAD 573 GAW++HCH+ H G+ FL + D Sbjct: 279 VGAGAWMYHCHVQSHSDMGMVGLFLVKKPD 308 >4GXF-A nrPDB Length = 279 Score = 62.2 bits (149), Expect = 7e-10, Method: Composition-based stats. Identities = 31/128 (24%), Positives = 49/128 (38%), Gaps = 24/128 (18%) Query: 113 NIMGPNIVANWGDTVEVTVINNLVTNGTSIHWHGIHQKDTNLHDGANGVTECPIPPKGGQ 172 ++ GP I N GDT+ + N + S+H HG+ + + DG + + + P GG Sbjct: 36 SVPGPLIEVNEGDTLHIEFTNTMDVRA-SLHVHGLDFEIS--SDGTA-MNKSDVEP-GGT 90 Query: 173 RTYRWRARQYGT------------SW-YHSHFSAQYG------NGVVGTIQINGPASLPY 213 RTY WR + G W YH H NG+ G + + + Sbjct: 91 RTYTWRTHKPGRRDDGTWRPGSAGYWHYHDHVVGTEHGTGGIRNGLYGPVIVRRKGDVLP 150 Query: 214 DIDLGVFP 221 D + Sbjct: 151 DATHTIVF 158 Score = 51.8 bits (122), Expect = 1e-06, Method: Composition-based stats. Identities = 26/124 (20%), Positives = 39/124 (31%), Gaps = 21/124 (16%) Query: 108 MLINGNIM--GPNIVANWGDTVEVTVINNLVTNGTSIHWHGIHQKDTNLHDGANGVTECP 165 M IN GP+ A GD VE+ +I ++H H D G+ P Sbjct: 161 MTINNRKPHTGPDFEATVGDRVEIVMIT------HGEYYHTFHMHGHRWADNRTGILTGP 214 Query: 166 ----------IPPKGGQRTYRWRARQ---YGTSWYHSHFSAQYGNGVVGTIQINGPASLP 212 I ++ A + G YH H + G+VG + P Sbjct: 215 DDPSRVIDNKITGPADSFGFQIIAGEGVGAGAWMYHCHVQSHSDMGMVGLFLVKKPDGTI 274 Query: 213 YDID 216 + Sbjct: 275 PGYE 278 Score = 46.0 bits (107), Expect = 5e-05, Method: Composition-based stats. Identities = 30/150 (20%), Positives = 51/150 (34%), Gaps = 28/150 (18%) Query: 428 SDINVDWGKPIIDYILTGNTSYPVSDNIVQVDAVDQWTYWLIENDPEGPFSLPHPMHLHG 487 D+ D I+ +T N P + + D+ +I + H H+HG Sbjct: 146 GDVLPDATHTIVFNDMTINNRKPHTGPDFEATVGDRVEIVMITHGEYY-----HTFHMHG 200 Query: 488 HDFLVLGRSPDVPAASQQRFVFDPAVDLARLNGDNPPR----RDTTMLPAGGWLLLAFRT 543 H + D+P R + T + G+ ++A Sbjct: 201 HRWA-------------------DNRTGILTGPDDPSRVIDNKITGPADSFGFQIIAGEG 241 Query: 544 DNPGAWLFHCHIAWHVSGGLSVDFLERPAD 573 GAW++HCH+ H G+ FL + D Sbjct: 242 VGAGAWMYHCHVQSHSDMGMVGLFLVKKPD 271 >4N8U-A nrPDB Length = 281 Score = 61.4 bits (147), Expect = 1e-09, Method: Composition-based stats. Identities = 34/128 (26%), Positives = 45/128 (35%), Gaps = 24/128 (18%) Query: 113 NIMGPNIVANWGDTVEVTVINNLVTNGTSIHWHGIHQKDTNLHDGANGVTECPIPPKGGQ 172 I GP I N GDT + V N L S+H HG+ + T DG + + P GG Sbjct: 38 TIPGPLIELNEGDTAHIEVENTLDV-PASLHVHGLDYEIT--SDGTK-LNRSDVEP-GGT 92 Query: 173 RTYRWRARQYGT------------SW-YHSHFSAQYG------NGVVGTIQINGPASLPY 213 RTY WR G W YH H G+ G + + + Sbjct: 93 RTYTWRTHAPGRRADGTWRAGSAGYWHYHDHVVGTEHGTGGIRKGLYGPVVVRRKGDVLP 152 Query: 214 DIDLGVFP 221 D + Sbjct: 153 DATHTIVF 160 Score = 46.0 bits (107), Expect = 5e-05, Method: Composition-based stats. Identities = 27/124 (21%), Positives = 39/124 (31%), Gaps = 21/124 (16%) Query: 108 MLINGN--IMGPNIVANWGDTVEVTVINNLVTNGTSIHWHGIHQKDTNLHDGANGVTECP 165 MLIN GPN A GD VE +I ++H H D G+ P Sbjct: 163 MLINNQPAHSGPNFEATVGDRVEFVMIT------HGEYYHTFHMHGHRWADNRTGLLTGP 216 Query: 166 IPPK--------GGQRTYRWRARQ-----YGTSWYHSHFSAQYGNGVVGTIQINGPASLP 212 P G ++ ++ G YH H + G+VG + Sbjct: 217 DDPSQVIDNKIVGPADSFGFQVIAGEGVGAGAWMYHCHVQSHSDMGMVGLFLVKKKDGTI 276 Query: 213 YDID 216 + Sbjct: 277 PGHE 280 Score = 42.5 bits (98), Expect = 6e-04, Method: Composition-based stats. Identities = 25/141 (17%), Positives = 46/141 (32%), Gaps = 20/141 (14%) Query: 428 SDINVDWGKPIIDYILTGNTSYPVSDNIVQVDAVDQWTYWLIENDPEGPFSLPHPMHLHG 487 D+ D I+ + N S + D+ + +I + H H+HG Sbjct: 148 GDVLPDATHTIVFNDMLINNQPAHSGPNFEATVGDRVEFVMITHGEYY-----HTFHMHG 202 Query: 488 HDFLVLGRSPDVPAASQQRFVFDPAVDLARLNGDNPPRRDTTMLPAGGWLLLAFRTDNPG 547 H + + +D + + G+ ++A G Sbjct: 203 HRWA-----DNRTGLLTGPDDPSQVIDNKIVGPADS----------FGFQVIAGEGVGAG 247 Query: 548 AWLFHCHIAWHVSGGLSVDFL 568 AW++HCH+ H G+ FL Sbjct: 248 AWMYHCHVQSHSDMGMVGLFL 268 >2VMJ-A nrPDB Length = 329 Score = 60.6 bits (145), Expect = 2e-09, Method: Composition-based stats. Identities = 35/151 (23%), Positives = 58/151 (38%), Gaps = 20/151 (13%) Query: 73 YEVSTPDTGVTQSYVFNLTEVDNWMGPDGVVKEKVMLINGNIMGPNIVANWGDTVEVTVI 132 +E +T + + E + G + M NG++ GP +V + GD V++T++ Sbjct: 23 HEQATKSGPKVVEFTMTIEEKKMVIDDKGTTLQA-MTFNGSMPGPTLVVHEGDYVQLTLV 81 Query: 133 NNLVTN-GTSIHWHGIHQKDTNLHDGANGVTECPIPPKGGQRTYRWRARQYGTSWYHSHF 191 N ++ +HG T GA P G Q T R++A + GT YH Sbjct: 82 NPATNAMPHNVDFHG----ATGALGGAKLTNVNP----GEQATLRFKADRSGTFVYHCTP 133 Query: 192 SAQYGNGVVGTIQI------NGPASLPYDID 216 + GT+ + P P D Sbjct: 134 HPF----MSGTLMVLPRDGLKDPQGKPLHYD 160 Score = 31.7 bits (70), Expect = 0.92, Method: Composition-based stats. Identities = 22/106 (20%), Positives = 32/106 (30%), Gaps = 10/106 (9%) Query: 500 PAASQQRFVFDPAVDLARLNGDNPPRRDTTMLPAGGWLLLAFRTDNPGAWLFHCHIAWH- 558 PA + D L G T + G L F+ D G +++HC H Sbjct: 83 PATNAMPHNVDFHGATGALGGAKL-----TNVNPGEQATLRFKADRSGTFVYHC--TPHP 135 Query: 559 VSGGLSVDFLERPADLRQRISQEDEDDFNRVCDEWRAYWPTNPYPK 604 G + L+ + D E+ Y P P K Sbjct: 136 FMSGTLMVLPRD--GLKDPQGKPLHYDRAYTIGEFDLYIPKGPDGK 179 >4WTQ-A nrPDB Length = 293 Score = 59.8 bits (143), Expect = 3e-09, Method: Composition-based stats. Identities = 44/244 (18%), Positives = 72/244 (29%), Gaps = 58/244 (23%) Query: 113 NIMGPNIVANWGDTVEVTVINNLVTNGTSIHWHGIHQKDTNLHDGANGVTECPIPPKGGQ 172 I GP I N GDT+ + N + S+H HG+ D + + + + P GG Sbjct: 38 TIPGPLIELNEGDTLHIEFENTMDVRA-SLHVHGL---DYEVSSDGTTLNKSDVEP-GGT 92 Query: 173 RTYRWRARQYGT------------SW-YHSHFSAQYG------NGVVGTIQINGPASLPY 213 RTY WR G W YH H G+ G + + + Sbjct: 93 RTYTWRTHAPGRRSDGTWRAGSAGYWHYHDHVVGTEHGTGGIRKGLYGPVIVRRKGDVLP 152 Query: 214 DIDLGVFPITDYYYRAADDLVHFTQNNAPPFSDNVLINGTAVNPNTGEGQYANVTLTPGK 273 D + +++LIN + G T+ G Sbjct: 153 DATHTIVF------------------------NDMLINNRPAH----SGPNFEATV--GD 182 Query: 274 RHRLRILNTSTENHFQVSLVNHTM--TVIAADMVPVNA-MTVDSLFLAVGQRYDVVIDAS 330 R ++ T E + + H P + VD+ + + + A Sbjct: 183 RVEFVMI-THGEYYHTFHMHGHRWADNRTGMLTGPDDPSQVVDNKIVGPADSFGFQVIAG 241 Query: 331 RAPD 334 Sbjct: 242 EGVG 245 Score = 45.2 bits (105), Expect = 8e-05, Method: Composition-based stats. Identities = 23/104 (22%), Positives = 34/104 (32%), Gaps = 19/104 (18%) Query: 116 GPNIVANWGDTVEVTVINNLVTNGTSIHWHGIHQKDTNLHDGANGVTECPIPPK------ 169 GPN A GD VE +I ++H H D G+ P P Sbjct: 173 GPNFEATVGDRVEFVMIT------HGEYYHTFHMHGHRWADNRTGMLTGPDDPSQVVDNK 226 Query: 170 --GGQRTYRWRARQ-----YGTSWYHSHFSAQYGNGVVGTIQIN 206 G ++ ++ G YH H + G+VG + Sbjct: 227 IVGPADSFGFQVIAGEGVGAGAWMYHCHVQSHSDMGLVGLFLVK 270 Score = 41.4 bits (95), Expect = 0.001, Method: Composition-based stats. Identities = 27/141 (19%), Positives = 46/141 (32%), Gaps = 20/141 (14%) Query: 428 SDINVDWGKPIIDYILTGNTSYPVSDNIVQVDAVDQWTYWLIENDPEGPFSLPHPMHLHG 487 D+ D I+ + N S + D+ + +I + H H+HG Sbjct: 148 GDVLPDATHTIVFNDMLINNRPAHSGPNFEATVGDRVEFVMITHGEYY-----HTFHMHG 202 Query: 488 HDFLVLGRSPDVPAASQQRFVFDPAVDLARLNGDNPPRRDTTMLPAGGWLLLAFRTDNPG 547 H + + VD + + G+ ++A G Sbjct: 203 HRWA-----DNRTGMLTGPDDPSQVVDNKIVGPADS----------FGFQVIAGEGVGAG 247 Query: 548 AWLFHCHIAWHVSGGLSVDFL 568 AW++HCH+ H GL FL Sbjct: 248 AWMYHCHVQSHSDMGLVGLFL 268 >5LHL-A nrPDB Length = 322 Score = 59.5 bits (142), Expect = 5e-09, Method: Composition-based stats. Identities = 33/128 (25%), Positives = 48/128 (37%), Gaps = 24/128 (18%) Query: 113 NIMGPNIVANWGDTVEVTVINNLVTNGTSIHWHGIHQKDTNLHDGANGVTECPIPPKGGQ 172 +I GP I N GDT+ V N + S+H HG+ + + DG + + P GG Sbjct: 74 SIPGPLIELNEGDTLHVEFENTMDV-PVSLHVHGLDYEIS--SDGTKQ-NKSHVEP-GGT 128 Query: 173 RTYRWRARQYGT------------SW-YHSHFSAQYG------NGVVGTIQINGPASLPY 213 RTY WR + G W YH H NG+ G + + + Sbjct: 129 RTYTWRTHEPGRRADGTWRAGSAGYWHYHDHVVGTEHGTGGIRNGLYGPVIVRRKGDVLP 188 Query: 214 DIDLGVFP 221 D + Sbjct: 189 DATHTIVF 196 Score = 50.6 bits (119), Expect = 2e-06, Method: Composition-based stats. Identities = 25/114 (21%), Positives = 36/114 (31%), Gaps = 19/114 (16%) Query: 116 GPNIVANWGDTVEVTVINNLVTNGTSIHWHGIHQKDTNLHDGANGVTECPIPPK------ 169 GPN A GD VE+ +I ++H H D G+ P P Sbjct: 209 GPNFEATVGDRVEIVMIT------HGEYYHTFHMHGHRWADNRTGMLTGPDDPSQVIDNK 262 Query: 170 ----GGQRTYRWRARQ---YGTSWYHSHFSAQYGNGVVGTIQINGPASLPYDID 216 ++ A + G YH H + G+VG + P D Sbjct: 263 ICGPADSFGFQIIAGEGVGAGAWMYHCHVQSHSDMGMVGLFLVKKPDGTIPGYD 316 Score = 44.8 bits (104), Expect = 1e-04, Method: Composition-based stats. Identities = 29/161 (18%), Positives = 52/161 (32%), Gaps = 24/161 (14%) Query: 428 SDINVDWGKPIIDYILTGNTSYPVSDNIVQVDAVDQWTYWLIENDPEGPFSLPHPMHLHG 487 D+ D I+ +T N + + D+ +I + H H+HG Sbjct: 184 GDVLPDATHTIVFNDMTINNRPAHTGPNFEATVGDRVEIVMITHGEYY-----HTFHMHG 238 Query: 488 HDFLVLGRSPDVPAASQQRFVFDPAVDLARLNGDNPPRRDTTM--LPAGGWLLLAFRTDN 545 H + A ++ + P ++ D+ + AG + Sbjct: 239 HRW----------ADNRTGMLTGPDDPSQVIDNKICGPADSFGFQIIAGEGV-------G 281 Query: 546 PGAWLFHCHIAWHVSGGLSVDFLERPADLRQRISQEDEDDF 586 GAW++HCH+ H G+ FL + D E Sbjct: 282 AGAWMYHCHVQSHSDMGMVGLFLVKKPDGTIPGYDPQEHAH 322 >3TBB-A nrPDB Length = 313 Score = 56.8 bits (135), Expect = 3e-08, Method: Composition-based stats. Identities = 32/128 (25%), Positives = 48/128 (37%), Gaps = 24/128 (18%) Query: 113 NIMGPNIVANWGDTVEVTVINNLVTNGTSIHWHGIHQKDTNLHDGANGVTECPIPPKGGQ 172 I GP I N GDT+ + N + S+H HG+ + + DG + + P GG Sbjct: 38 TIPGPLIELNEGDTLHIE-FENTMDVPVSLHVHGLDYEIS--SDGTKQ-SRSDVEP-GGT 92 Query: 173 RTYRWRAR----------QYGT--SW-YHSHFSAQYG------NGVVGTIQINGPASLPY 213 RTY WR + G+ W YH H NG+ G + + + Sbjct: 93 RTYTWRTHVPGRRADGTWRAGSAGYWHYHDHVVGTEHGTGGIRNGLYGPVIVRRKGDVLP 152 Query: 214 DIDLGVFP 221 D + Sbjct: 153 DRTHTIVF 160 Score = 49.1 bits (115), Expect = 5e-06, Method: Composition-based stats. Identities = 27/142 (19%), Positives = 44/142 (30%), Gaps = 29/142 (20%) Query: 95 NWMGPDGVVKEKVMLINGNIM-------GPNIVANWGDTVEVTVINNLVTNGTSIHWHGI 147 + PD + ++ N + GP+ A GD VE +I ++H Sbjct: 148 GDVLPD---RTHTIVFNDMTINNRPAHTGPDFEATVGDRVEFVMIT------HGEYYHTF 198 Query: 148 HQKDTNLHDGANGVTECPIPPK--------GGQRTYRWRARQ-----YGTSWYHSHFSAQ 194 H D G+ P P G ++ ++ G YH H + Sbjct: 199 HLHGHRWADNRTGMLTGPDDPSQVIDNKICGPADSFGFQVIAGEGVGAGAWMYHCHVQSH 258 Query: 195 YGNGVVGTIQINGPASLPYDID 216 G+VG + P D Sbjct: 259 SDMGMVGLFLVKKPDGTIPGYD 280 Score = 45.6 bits (106), Expect = 7e-05, Method: Composition-based stats. Identities = 29/146 (19%), Positives = 53/146 (36%), Gaps = 20/146 (13%) Query: 428 SDINVDWGKPIIDYILTGNTSYPVSDNIVQVDAVDQWTYWLIENDPEGPFSLPHPMHLHG 487 D+ D I+ +T N + + D+ + +I + H HLHG Sbjct: 148 GDVLPDRTHTIVFNDMTINNRPAHTGPDFEATVGDRVEFVMITHGEYY-----HTFHLHG 202 Query: 488 HDFLVLGRSPDVPAASQQRFVFDPAVDLARLNGDNPPRRDTTMLPAGGWLLLAFRTDNPG 547 H + A ++ + P ++ D+ G+ ++A G Sbjct: 203 HRW----------ADNRTGMLTGPDDPSQVIDNKICGPADS-----FGFQVIAGEGVGAG 247 Query: 548 AWLFHCHIAWHVSGGLSVDFLERPAD 573 AW++HCH+ H G+ FL + D Sbjct: 248 AWMYHCHVQSHSDMGMVGLFLVKKPD 273 >1NDS-A nrPDB Length = 330 Score = 53.7 bits (127), Expect = 2e-07, Method: Composition-based stats. Identities = 35/162 (21%), Positives = 62/162 (38%), Gaps = 22/162 (13%) Query: 100 DGVVKEKVMLINGNIMGPNIVANWGDTVEVTVINNLVTN-GTSIHWHGIHQKDTNLHDGA 158 DG + M NG++ GP +V + GD +E+T++N + ++ +H Sbjct: 45 DGTTAQA-MTFNGSVPGPTLVVHEGDYIELTLVNPATNSMPHNVDFH-------AATGAL 96 Query: 159 NGVTECPIPPKGGQRTYRWRARQYGTSWYHSHFSA----QYGNGVVGTIQINGPASLP-- 212 G + P G + R++A + GT YH + +G+ G + + L Sbjct: 97 GGAGLTQVVP-GQEAVLRFKADRSGTFVYHCAPAGMVPWHVVSGMNGALMVLPRDGLRDA 155 Query: 213 ------YDIDLGVFPITDYYYRAADDLVHFTQNNAPPFSDNV 248 YD + Y +AAD A ++D V Sbjct: 156 AGAALAYDRVYTIGESDLYVPKAADGNYSDYPALASAYADTV 197 Score = 32.1 bits (71), Expect = 0.68, Method: Composition-based stats. Identities = 17/71 (23%), Positives = 25/71 (35%), Gaps = 5/71 (7%) Query: 533 AGGWLLLAFRTDNPGAWLFHC----HIAWHVSGGL-SVDFLERPADLRQRISQEDEDDFN 587 G +L F+ D G +++HC + WHV G+ + LR D Sbjct: 106 PGQEAVLRFKADRSGTFVYHCAPAGMVPWHVVSGMNGALMVLPRDGLRDAAGAALAYDRV 165 Query: 588 RVCDEWRAYWP 598 E Y P Sbjct: 166 YTIGESDLYVP 176 >1N70-A nrPDB Length = 334 Score = 52.9 bits (125), Expect = 4e-07, Method: Composition-based stats. Identities = 34/150 (22%), Positives = 54/150 (36%), Gaps = 13/150 (8%) Query: 88 FNLTEVDNWMGPDGVVKEKVMLINGNIMGPNIVANWGDTVEVTVINNLVTNGTSIHWHGI 147 F + ++ + D + M +G+I GP ++ + GD VE+T+IN T H Sbjct: 33 FEMRIIEKEVQLDEDAYLQAMTFDGSIPGPLMIVHEGDYVELTLIN--PPENTMPHNIDF 90 Query: 148 HQKDTNLHDGANGVTECPIPPKGGQRTYRWRARQYGTSWYHSHFSA-----QYGNGVVGT 202 H G I P G + R++A + G YH +G+ G Sbjct: 91 HAATGA----LGGGGLTLINP-GEKVVLRFKATRAGAFVYHCAPGGPMIPWHVVSGMAGC 145 Query: 203 IQINGPASLPYDIDLGVFPITDYYYRAADD 232 I + L D + YY D Sbjct: 146 IMVLPRDGLK-DHEGKPVRYDTVYYIGESD 174 Score = 34.8 bits (78), Expect = 0.10, Method: Composition-based stats. Identities = 12/39 (30%), Positives = 21/39 (53%), Gaps = 5/39 (12%) Query: 531 LPAGGWLLLAFRTDNPGAWLFHC-----HIAWHVSGGLS 564 + G ++L F+ GA+++HC I WHV G++ Sbjct: 105 INPGEKVVLRFKATRAGAFVYHCAPGGPMIPWHVVSGMA 143 >1SDD-B nrPDB Length = 647 Score = 52.1 bits (123), Expect = 7e-07, Method: Composition-based stats. Identities = 60/323 (18%), Positives = 110/323 (34%), Gaps = 49/323 (15%) Query: 63 WSDGFDINTDYEVSTPDTGVTQSYVFN--LTEVDNWMGPDGVVKEKVMLINGNIMGPNIV 120 W + +D P+ V + VF L + P G +E + I+GP I Sbjct: 18 WDYSKFVQSDDVDYVPEDTVYKKVVFRKYLDSTFTKLDPQGEYEEHL-----GILGPVIR 72 Query: 121 ANWGDTVEVTVINNLVTNGTSIHWHGI----HQKDTNLHDGAN--GVTECPIPPKGGQRT 174 A D ++V NL + S+H HG+ + D + + I P T Sbjct: 73 AEVDDVIQVR-FKNLASRPYSLHAHGLSYEKSSEGKTYEDDSPEWFKEDNAIQPN-KTYT 130 Query: 175 YRWRA------RQYGT---SW-YHSHFSAQ--YGNGVVGTIQI------NGPASLPYDID 216 Y W A G+ +W Y+S + + +G++G + I + ++P D+ Sbjct: 131 YVWHATTRSGPENPGSACRAWAYYSAVNPEKDIHSGLIGPLLICRKGTLDKETNMPVDMR 190 Query: 217 LGVFPITDYYYRAADDLVHFTQNNAPP----FSDNVLINGTAVNP-NTGEGQYANVTLTP 271 V + D+ + + P + + + N + N + + Sbjct: 191 EFVLL-----FMVFDEKKSWYYDKKPTRSWRRASSEVKNSHEFHAINGMIYNLPGLRMYE 245 Query: 272 GKRHRLRILNTSTENHFQVSLVNHTMTVIAADMVPVNAMTVDSLFLAVGQRYDVVIDASR 331 + RL +LN V + H T++ + L G + + AS+ Sbjct: 246 QEWVRLHLLNLGGSRDIHV-VHFHGQTLLEN---GTQQHQLGVWPLLPGSFKTLEMKASK 301 Query: 332 APDNYWFNVTFGGQAACGGSLNP 354 +W T G+ G P Sbjct: 302 P--GWWLLDTEVGEIQRAGMQTP 322 >3T9W-A nrPDB Length = 299 Score = 51.4 bits (121), Expect = 1e-06, Method: Composition-based stats. Identities = 26/93 (27%), Positives = 39/93 (41%), Gaps = 15/93 (16%) Query: 481 HPMHLHGHDFLVLGRSPDVPAASQQRFVFDPAVDLARLNGDNPPRRDTTMLPAGGWLLLA 540 H HLHGH +L + + P +D+ LN G+ ++A Sbjct: 212 HTFHLHGHRWL-----DNRTGMRTSEYDPSPLIDIKDLNPGVS----------FGFQVIA 256 Query: 541 FRTDNPGAWLFHCHIAWHVSGGLSVDFLERPAD 573 PG W++HCH+ H G++ FL R AD Sbjct: 257 GEGVGPGMWMYHCHVQNHSDMGMAGMFLVRNAD 289 Score = 46.0 bits (107), Expect = 5e-05, Method: Composition-based stats. Identities = 26/115 (22%), Positives = 40/115 (34%), Gaps = 30/115 (26%) Query: 113 NIMGPNIVANWGDTVEVTVINNLVTNGTSIHWHGI---HQKDTNLHDGANGVTECPIPPK 169 + GP + GDT+E+ ++N S+H HG+ D L +G+ + Sbjct: 54 TVPGPVLEMWEGDTLEIDLVN-TTDRVLSLHPHGVDYDVNSDGTLMNGSAVMP------- 105 Query: 170 GGQRTYRWR------------ARQYGTSW-YHSHFSAQYG------NGVVGTIQI 205 G R Y WR A W YH H G+ G + + Sbjct: 106 GQTRRYTWRSHVGYRRADGSWAEGTAGYWHYHDHAMGTEHGTEGVLKGLYGALVV 160 Score = 39.0 bits (89), Expect = 0.006, Method: Composition-based stats. Identities = 23/117 (19%), Positives = 35/117 (29%), Gaps = 20/117 (17%) Query: 116 GPNIVANWGDTVEVTVINNLVTNGTSIHWHGIHQKDTNLHDGANGVTECPIPPK------ 169 P AN G+ VE I G ++H H D G+ P Sbjct: 189 APTFEANLGERVEWIAI------GHGSNFHTFHLHGHRWLDNRTGMRTSEYDPSPLIDIK 242 Query: 170 ----GGQRTYRWRARQ---YGTSWYHSHFSAQYGNGVVGTIQI-NGPASLPYDIDLG 218 G ++ A + G YH H G+ G + N ++P + Sbjct: 243 DLNPGVSFGFQVIAGEGVGPGMWMYHCHVQNHSDMGMAGMFLVRNADGTMPAGVHEH 299 >5AKR-A nrPDB Length = 378 Score = 50.2 bits (118), Expect = 2e-06, Method: Composition-based stats. Identities = 33/157 (21%), Positives = 53/157 (33%), Gaps = 13/157 (8%) Query: 82 VTQSYVFNLTEVDNWMGPDGVVKEKVMLINGNIMGPNIVANWGDTVEVTVINNLVTNGTS 141 + + E + +G + M NG++ GP +V + D VE+ +IN T Sbjct: 75 RVVEFTMTIEEKKLVIDREG-TEIHAMTFNGSVPGPLMVVHENDYVELRLIN--PDTNTL 131 Query: 142 IHWHGIHQKDTNLHDGANGVTECPIPPKGGQRTYRWRARQYGTSWYHSHFSA----QYGN 197 +H H G + P G + T R++A + G YH + Sbjct: 132 LHNIDFHAATGA----LGGGALTQVNP-GEETTLRFKATKPGVFVYHCAPEGMVPWHVTS 186 Query: 198 GVVGTIQINGPASLPYDIDLGVFPITDYYYRAADDLV 234 G+ G I + L D YY D Sbjct: 187 GMNGAIMVLPRDGLK-DEKGQPLTYDKIYYVGEQDFY 222 Score = 38.7 bits (88), Expect = 0.008, Method: Composition-based stats. Identities = 17/74 (22%), Positives = 27/74 (36%), Gaps = 5/74 (6%) Query: 530 MLPAGGWLLLAFRTDNPGAWLFHC----HIAWHVSGGL-SVDFLERPADLRQRISQEDED 584 + G L F+ PG +++HC + WHV+ G+ + L+ Q Sbjct: 151 QVNPGEETTLRFKATKPGVFVYHCAPEGMVPWHVTSGMNGAIMVLPRDGLKDEKGQPLTY 210 Query: 585 DFNRVCDEWRAYWP 598 D E Y P Sbjct: 211 DKIYYVGEQDFYVP 224 >2Y1A-A nrPDB Length = 340 Score = 50.2 bits (118), Expect = 3e-06, Method: Composition-based stats. Identities = 33/157 (21%), Positives = 53/157 (33%), Gaps = 13/157 (8%) Query: 82 VTQSYVFNLTEVDNWMGPDGVVKEKVMLINGNIMGPNIVANWGDTVEVTVINNLVTNGTS 141 + + E + +G + M NG++ GP +V + D VE+ +IN T Sbjct: 37 RVVEFTMTIEEKKLVIDREG-TEIHAMTFNGSVPGPLMVVHENDYVELRLIN--PDTNTL 93 Query: 142 IHWHGIHQKDTNLHDGANGVTECPIPPKGGQRTYRWRARQYGTSWYHSHFSA----QYGN 197 +H H G + P G + T R++A + G YH + Sbjct: 94 LHNIDFHAATGA----LGGGALTQVNP-GEETTLRFKATKPGVFVYHCAPEGMVPWHVTS 148 Query: 198 GVVGTIQINGPASLPYDIDLGVFPITDYYYRAADDLV 234 G+ G I + L D YY D Sbjct: 149 GMNGAIMVLPRDGLK-DEKGQPLTYDKIYYVGEQDFY 184 Score = 38.3 bits (87), Expect = 0.009, Method: Composition-based stats. Identities = 17/74 (22%), Positives = 27/74 (36%), Gaps = 5/74 (6%) Query: 530 MLPAGGWLLLAFRTDNPGAWLFHC----HIAWHVSGGL-SVDFLERPADLRQRISQEDED 584 + G L F+ PG +++HC + WHV+ G+ + L+ Q Sbjct: 113 QVNPGEETTLRFKATKPGVFVYHCAPEGMVPWHVTSGMNGAIMVLPRDGLKDEKGQPLTY 172 Query: 585 DFNRVCDEWRAYWP 598 D E Y P Sbjct: 173 DKIYYVGEQDFYVP 186 >1AS8-A nrPDB Length = 343 Score = 47.1 bits (110), Expect = 2e-05, Method: Composition-based stats. Identities = 28/117 (23%), Positives = 43/117 (36%), Gaps = 11/117 (9%) Query: 100 DGVVKEKVMLINGNIMGPNIVANWGDTVEVTVINNLVTNGTSIHWHGIHQKDTNLHDGAN 159 D + M NG + GP +V + D +E+T+IN T +H H Sbjct: 57 DAGTEVHAMAFNGTVPGPLMVVHQDDYLELTLIN--PETNTLMHNIDFHAATGA----LG 110 Query: 160 GVTECPIPPKGGQRTYRWRARQYGTSWYHSHFSA----QYGNGVVGTIQINGPASLP 212 G I P G + R++A + G YH +G+ G I + L Sbjct: 111 GGGLTEINP-GEKTILRFKATKPGVFVYHCAPPGMVPWHVVSGMNGAIMVLPREGLH 166 Score = 34.8 bits (78), Expect = 0.13, Method: Composition-based stats. Identities = 11/37 (29%), Positives = 19/37 (51%), Gaps = 4/37 (10%) Query: 531 LPAGGWLLLAFRTDNPGAWLFHC----HIAWHVSGGL 563 + G +L F+ PG +++HC + WHV G+ Sbjct: 117 INPGEKTILRFKATKPGVFVYHCAPPGMVPWHVVSGM 153 >4BDV-A nrPDB Length = 760 Score = 42.9 bits (99), Expect = 4e-04, Method: Composition-based stats. Identities = 33/183 (18%), Positives = 63/183 (34%), Gaps = 22/183 (12%) Query: 102 VVKEKVMLINGNIMGPNIVANWGDTVEVTVINNLVTNGTSIHWHGIHQK----DTNLHDG 157 + + I+GP + GDT+ + + N + +I+ HGI L G Sbjct: 436 FKTREAIQHESGILGPLLYGEVGDTLLI-IFKNQASRPYNIYPHGITDVRPLYSRRLPKG 494 Query: 158 ANGVTECPIPPKGGQRTYRWRA----------RQYGTSWYHSHFSAQ--YGNGVVGTIQI 205 + + PI P G Y+W + T +Y S + + +G++G + I Sbjct: 495 VKHLKDFPILP-GEIFKYKWTVTVEDGPTKSDPRCLTRYYSSFVNMERDLASGLIGPLLI 553 Query: 206 NGPASLPYDIDLGVFPITDYYYRAADDLVHFTQNN-APPFSDNVLINGTAVNPNTGEGQY 264 S+ + ++D + ++ L N V E Q Sbjct: 554 CYKESVDQRGNQ---IMSDKRNVILFSVFDENRSWYLTENIQRFLPNPAGVQLEDPEFQA 610 Query: 265 ANV 267 +N+ Sbjct: 611 SNI 613 Score = 32.9 bits (73), Expect = 0.47, Method: Composition-based stats. Identities = 27/122 (22%), Positives = 45/122 (36%), Gaps = 26/122 (21%) Query: 103 VKEKVMLINGNIMGPNIVANWGDTVEVTVINNLVTNGTSIHWHGIHQKDTNLHDGANGVT 162 + M + +GP I A DTV +T+ N + ++ S+H G+ +GA Sbjct: 64 PRPPWMGL----LGPTIQAEVYDTVVITLKN-MASHPVSLHAVGV--SYWKASEGAEYDD 116 Query: 163 ECPIPPK-------GGQRTYRWRA-----RQYG-----TSWYHSH--FSAQYGNGVVGTI 203 + K GG TY W+ T Y SH +G++G + Sbjct: 117 QTSQREKEDDKVFPGGSHTYVWQVLKENGPMASDPLCLTYSYLSHVDLVKDLNSGLIGAL 176 Query: 204 QI 205 + Sbjct: 177 LV 178 Score = 32.1 bits (71), Expect = 0.72, Method: Composition-based stats. Identities = 23/149 (15%), Positives = 46/149 (30%), Gaps = 21/149 (14%) Query: 427 GSDINVDWGKPIIDYILTGNTSYPVSDNIVQVDAVDQWTYWLIENDPEGPFSLPHPMH-- 484 G+ I D I+ + N S+ +++NI + +E+ ++ H ++ Sbjct: 563 GNQIMSDKRNVILFSVFDENRSWYLTENI--QRFLPNPAGVQLEDPEFQASNIMHSINGY 620 Query: 485 ----------LHGHDFLVLGRSPDVPAASQQRFVFDPAVDLARLNGDNPPRRDTTMLPAG 534 LH + + + F DT L Sbjct: 621 VFDSLQLSVCLHEVAYWYILSIG-------AQTDFLSVFFSGYTFKHKMVYEDTLTLFPF 673 Query: 535 GWLLLAFRTDNPGAWLFHCHIAWHVSGGL 563 + +NPG W+ CH + + G+ Sbjct: 674 SGETVFMSMENPGLWILGCHNSDFRNRGM 702 >2IWK-A nrPDB Length = 642 Score = 36.7 bits (83), Expect = 0.030, Method: Composition-based stats. Identities = 19/99 (19%), Positives = 33/99 (33%), Gaps = 13/99 (13%) Query: 113 NIMGPNIVANWGDTVEVTVINNLVTNGTSIHWHGIHQKDTNLHDGANGVTECPIPPKGGQ 172 + P+ GD V V V N + + HG G +GV + P+ Sbjct: 556 SFSQPSFTVKEGDEVTVIVTNLDEIDDLT---HGFTM-------GNHGV-AMEVGPQ-QT 603 Query: 173 RTYRWRARQYGTSWYHSH-FSAQYGNGVVGTIQINGPAS 210 + + A G WY+ F + G + + + Sbjct: 604 SSVTFVAANPGVYWYYCQWFCHALHMEMRGRMFVEPKGA 642 >1QNI-A nrPDB Length = 581 Score = 36.4 bits (82), Expect = 0.039, Method: Composition-based stats. Identities = 17/89 (19%), Positives = 29/89 (32%), Gaps = 13/89 (14%) Query: 120 VANWGDTVEVTVINNLVTNGTSIHWHGIHQKDTNLHDGANGVTECPIPPKGGQRTYRWRA 179 GD V V + N + + HG N I P+ + + A Sbjct: 504 KVKEGDEVTVYITNLDMVEDVT---HGFCM--------VNHGVSMEISPQ-QTASVTFTA 551 Query: 180 RQYGTSWYHSH-FSAQYGNGVVGTIQING 207 + G WY+ + F +VG + + Sbjct: 552 GKPGVYWYYCNWFCHALHMEMVGRMLVEA 580 >4BDV-B nrPDB Length = 685 Score = 36.0 bits (81), Expect = 0.055, Method: Composition-based stats. Identities = 43/321 (13%), Positives = 78/321 (24%), Gaps = 72/321 (22%) Query: 302 ADMVPVNAMTVDSL-----FLAVGQRYDV----VIDA-SRAPDNYWF--------NVTFG 343 D + L L R +V ++ ++A Y F Sbjct: 92 TDGSFTQPLYRGELNEHLGLLGPYIRAEVEDNIMVTFRNQASRPYSFYSSLISYEEDQRQ 151 Query: 344 GQAACGGSLNPHPAAIFHYAGAPGGLPTDEGTPPVDHQCLDTLDVRPVVPRSVPV----- 398 G + P+ + + PT + +D+ V + Sbjct: 152 GAEPRKNFVKPNETKTYFWKVQHHMAPTKDEFDCKAWAYFSDVDLEKDVHSGLIGPLLVC 211 Query: 399 -----NSFVKRPDNTLPVAL---DLTGTPLFVWKVN-----GSDINVDWGKPIID----- 440 N R AL T + + N + N+ P Sbjct: 212 HTNTLNPAHGRQVTVQEFALFFTIFDETKSWYFTENMERNCRAPCNIQMEDPTFKENYRF 271 Query: 441 YILTGNTSYPVSDNIVQVDAVDQWTYWLIENDPEGPFSLPHPMHLHGHDFLVLGRSPDVP 500 + + G + ++ D +W + ++ H +H GH F V + Sbjct: 272 HAINGYIMDTLPGLVMAQDQRIRWYLLSMGSNENI-----HSIHFSGHVFTVRKKEEYKM 326 Query: 501 AASQQRFVFDPAVDLARLNGDNPPRRDTTMLPAGGWLLLAFRTDNPGAWLFHCHIAWHVS 560 A L G + + G W C I H+ Sbjct: 327 ALYN--------------------------LYPGVFETVEMLPSKAGIWRVECLIGEHLH 360 Query: 561 GGLSVDFLERPADLRQRISQE 581 G+S FL + + Sbjct: 361 AGMSTLFLVYSNKCQTPLGMA 381 >2R7E-B nrPDB Length = 770 Score = 35.6 bits (80), Expect = 0.072, Method: Composition-based stats. Identities = 43/321 (13%), Positives = 78/321 (24%), Gaps = 72/321 (22%) Query: 302 ADMVPVNAMTVDSL-----FLAVGQRYDV----VIDA-SRAPDNYWF--------NVTFG 343 D + L L R +V ++ ++A Y F Sbjct: 177 TDGSFTQPLYRGELNEHLGLLGPYIRAEVEDNIMVTFRNQASRPYSFYSSLISYEEDQRQ 236 Query: 344 GQAACGGSLNPHPAAIFHYAGAPGGLPTDEGTPPVDHQCLDTLDVRPVVPRSVPV----- 398 G + P+ + + PT + +D+ V + Sbjct: 237 GAEPRKNFVKPNETKTYFWKVQHHMAPTKDEFDCKAWAYSSDVDLEKDVHSGLIGPLLVC 296 Query: 399 -----NSFVKRPDNTLPVAL---DLTGTPLFVWKVN-----GSDINVDWGKPIID----- 440 N R AL T + + N + N+ P Sbjct: 297 HTNTLNPAHGRQVTVQEFALFFTIFDETKSWYFTENMERNCRAPCNIQMEDPTFKENYRF 356 Query: 441 YILTGNTSYPVSDNIVQVDAVDQWTYWLIENDPEGPFSLPHPMHLHGHDFLVLGRSPDVP 500 + + G + ++ D +W + ++ H +H GH F V + Sbjct: 357 HAINGYIMDTLPGLVMAQDQRIRWYLLSMGSNENI-----HSIHFSGHVFTVRKKEEYKM 411 Query: 501 AASQQRFVFDPAVDLARLNGDNPPRRDTTMLPAGGWLLLAFRTDNPGAWLFHCHIAWHVS 560 A L G + + G W C I H+ Sbjct: 412 ALYN--------------------------LYPGVFETVEMLPSKAGIWRVECLIGEHLH 445 Query: 561 GGLSVDFLERPADLRQRISQE 581 G+S FL + + Sbjct: 446 AGMSTLFLVYSNKCQTPLGMA 466 >5K8D-B nrPDB Length = 865 Score = 34.8 bits (78), Expect = 0.12, Method: Composition-based stats. Identities = 43/321 (13%), Positives = 78/321 (24%), Gaps = 72/321 (22%) Query: 302 ADMVPVNAMTVDSL-----FLAVGQRYDV----VIDA-SRAPDNYWF--------NVTFG 343 D + L L R +V ++ ++A Y F Sbjct: 46 TDGSFTQPLYRGELNEHLGLLGPYIRAEVEDNIMVTFRNQASRPYSFYSSLISYEEDQRQ 105 Query: 344 GQAACGGSLNPHPAAIFHYAGAPGGLPTDEGTPPVDHQCLDTLDVRPVVPRSVPV----- 398 G + P+ + + PT + +D+ V + Sbjct: 106 GAEPRKNFVKPNETKTYFWKVQHHMAPTKDEFDCKAWAYFSDVDLEKDVHSGLIGPLLVC 165 Query: 399 -----NSFVKRPDNTLPVAL---DLTGTPLFVWKVN-----GSDINVDWGKPIID----- 440 N R AL T + + N + N+ P Sbjct: 166 HTNTLNPAHGRQVTVQEFALFFTIFDETKSWYFTENMERNCRAPCNIQMEDPTFKENYRF 225 Query: 441 YILTGNTSYPVSDNIVQVDAVDQWTYWLIENDPEGPFSLPHPMHLHGHDFLVLGRSPDVP 500 + + G + ++ D +W + ++ H +H GH F V + Sbjct: 226 HAINGYIMDTLPGLVMAQDQRIRWYLLSMGSNENI-----HSIHFSGHVFTVRKKEEYKM 280 Query: 501 AASQQRFVFDPAVDLARLNGDNPPRRDTTMLPAGGWLLLAFRTDNPGAWLFHCHIAWHVS 560 A L G + + G W C I H+ Sbjct: 281 ALYN--------------------------LYPGVFETVEMLPSKAGIWRVECLIGEHLH 314 Query: 561 GGLSVDFLERPADLRQRISQE 581 G+S FL + + Sbjct: 315 AGMSTLFLVYSNKCQTPLGMA 335 >3SBP-A nrPDB Length = 638 Score = 34.4 bits (77), Expect = 0.16, Method: Composition-based stats. Identities = 19/92 (20%), Positives = 28/92 (30%), Gaps = 19/92 (20%) Query: 120 VANWGDTVEVTVINNLVTNGTSIHWHGIHQKDTNLHDGANGVTECPIPPKGGQRTYRWRA 179 GD V VT+ N S HG N I P+ + + A Sbjct: 561 TVKQGDEVTVTITNIDQIEDVS---HGFVV--------VNHGVSMEISPQ-QTSSITFVA 608 Query: 180 RQYGTSWYH----SHFSAQYGNGVVGTIQING 207 + G WY+ H +VG + + Sbjct: 609 DKPGLHWYYCSWFCHA---LHMEMVGRMMVEP 637 >1FWX-A nrPDB Length = 595 Score = 34.0 bits (76), Expect = 0.20, Method: Composition-based stats. Identities = 19/92 (20%), Positives = 29/92 (31%), Gaps = 13/92 (14%) Query: 120 VANWGDTVEVTVINNLVTNGTSIHWHGIHQKDTNLHDGANGVTECPIPPKGGQRTYRWRA 179 GD V V V N + + HG G GV I P+ + + A Sbjct: 516 TVKEGDEVTVIVTNLDEIDDLT---HGFTM-------GNYGV-AMEIGPQMTS-SVTFVA 563 Query: 180 RQYGTSWYHSH-FSAQYGNGVVGTIQINGPAS 210 G WY+ F + G + + + Sbjct: 564 ANPGVYWYYCQWFCHALHMEMRGRMLVEPKEA 595 >1QHQ-A nrPDB Length = 140 Score = 34.0 bits (76), Expect = 0.22, Method: Composition-based stats. Identities = 23/75 (30%), Positives = 29/75 (38%), Gaps = 1/75 (1%) Query: 491 LVLGRSPDVPAASQQRFVFDPAVDLARLNGDNP-PRRDTTMLPAGGWLLLAFRTDNPGAW 549 VL D AA+ + A L D P T ML AG + FRT PG + Sbjct: 59 WVLVNGGDDVAAAVNTAAQNNADALFVPPPDTPNALAWTAMLNAGESGSVTFRTPAPGTY 118 Query: 550 LFHCHIAWHVSGGLS 564 L+ C H G+ Sbjct: 119 LYICTFPGHYLAGMK 133 Score = 32.9 bits (73), Expect = 0.45, Method: Composition-based stats. Identities = 12/52 (23%), Positives = 19/52 (36%) Query: 156 DGANGVTECPIPPKGGQRTYRWRARQYGTSWYHSHFSAQYGNGVVGTIQING 207 D N + + G + +R GT Y F Y G+ GT+ + Sbjct: 89 DTPNALAWTAMLNAGESGSVTFRTPAPGTYLYICTFPGHYLAGMKGTLTVTP 140 >2RAC-A nrPDB Length = 105 Score = 31.7 bits (70), Expect = 1.00, Method: Composition-based stats. Identities = 18/90 (20%), Positives = 28/90 (31%), Gaps = 17/90 (18%) Query: 117 PNIVANWGDTVEVTVINNLVTNGTSIHWHGIHQKDTNLHDGANGVTECPIPPKGGQRTYR 176 P + GDTV T IN ++H+ G G P ++ Y Sbjct: 33 PELHVKVGDTV--TWINR-EAMPHNVHF----------VAGVLGEAALKGPMMKKEQAYS 79 Query: 177 WRARQYGTSWYHSHFSAQYGNGVVGTIQIN 206 + GT YH + G + + Sbjct: 80 LTFTEAGTYDYHCTPHPF----MRGKVVVE 105 >1CUR-A nrPDB Length = 155 Score = 31.3 bits (69), Expect = 1.1, Method: Composition-based stats. Identities = 23/95 (24%), Positives = 31/95 (32%), Gaps = 4/95 (4%) Query: 116 GPNIVANWGDTVEVTVINNLVTNGTS--IHWHGIHQKDTNLHDG-ANGVTECPIPPKGGQ 172 P + G TV+VT IN G S I G + D G P+P G Sbjct: 61 NPTLEIPAGATVDVTFINTNKGFGHSFDITKKGPPYAVMPVIDPIVAGTGFSPVPKDGKF 120 Query: 173 RTYRWR-ARQYGTSWYHSHFSAQYGNGVVGTIQIN 206 + GT +Y G+ G I + Sbjct: 121 GYTDFTWHPTAGTYYYVCQIPGHAATGMFGKIVVK 155 >4DKN-A nrPDB Length = 223 Score = 31.3 bits (69), Expect = 1.2, Method: Composition-based stats. Identities = 11/51 (21%), Positives = 17/51 (33%), Gaps = 4/51 (7%) Query: 474 EGPFSLPHPMHLH----GHDFLVLGRSPDVPAASQQRFVFDPAVDLARLNG 520 P H +HLH GH+F ++G P A + + Sbjct: 4 GMPLPATHDIHLHGSINGHEFDMVGGGKGDPNAGSLVTTAKSTKGALKFSP 54 >1Z01-A nrPDB Length = 446 Score = 31.3 bits (69), Expect = 1.3, Method: Composition-based stats. Identities = 21/64 (32%), Positives = 28/64 (43%), Gaps = 9/64 (14%) Query: 51 EPTCNTPSNRACWSDGFDINTDYEVSTPDTGVTQSYVFNLTEVDNWMGPDGVVKEKVMLI 110 +PTC T S +CW GF + +TG + V N D +G GV V + Sbjct: 94 KPTCFTKSTISCWYHGFTFDL-------ETGKLVTIVANPE--DKLIGTTGVTTYPVHEV 144 Query: 111 NGNI 114 NG I Sbjct: 145 NGMI 148 >2AAN-A nrPDB Length = 139 Score = 31.0 bits (68), Expect = 1.5, Method: Composition-based stats. Identities = 11/52 (21%), Positives = 18/52 (34%), Gaps = 1/52 (1%) Query: 155 HDGANGVTECPIPPKGGQRTYRWRARQYGTSWYHSHFSAQYGNGVVGTIQIN 206 D +N + E P+ + A GT Y Y + G + +N Sbjct: 89 ADKSNIIAESPLANGNETVEVTFTAPAAGTYLYICTVPGHYPL-MQGKLVVN 139 >1FSK-B nrPDB Length = 214 Score = 31.0 bits (68), Expect = 1.6, Method: Composition-based stats. Identities = 25/139 (17%), Positives = 38/139 (27%), Gaps = 21/139 (15%) Query: 314 SLFLAVGQRYDVVIDASRAPDNYWF----NVTFGGQAACGGSLNPHPAAIFHYAGAPGGL 369 S+ ++VG+R + AS D Y F + G N + + G+ Sbjct: 10 SMSVSVGERVTLSCKASENVDTYVFWFQQKPDQSPKLLLYGPSNRYTGVPDRFTGSGST- 68 Query: 370 PTDEGTPPVDHQCLDTLDVRPVVPRSVPVNSFVKRPDNTLPVALDLTGTPLFVWKVNGSD 429 TD Q D D S P G K + Sbjct: 69 -TDFTLTISSVQAEDLADYHCGQSYSYP---------------YTFGGGTKLEIKRADAA 112 Query: 430 INVDWGKPIIDYILTGNTS 448 V P + + +G S Sbjct: 113 PTVSIFPPSSEQLTSGGAS 131 >1OGO-X nrPDB Length = 574 Score = 30.6 bits (67), Expect = 2.2, Method: Composition-based stats. Identities = 13/54 (24%), Positives = 21/54 (38%), Gaps = 2/54 (3%) Query: 138 NGTSIHWHGIHQKDTNLHDGANGVTECPIPPKG--GQRTYRWRARQYGTSWYHS 189 +GT+ + H T HD T+ P+ P Y + GT+ +H Sbjct: 1 HGTTANTHCGADFCTWWHDSGEINTQTPVQPGNVRQSHKYSVQVSLAGTNNFHD 54 >4H1O-A nrPDB Length = 560 Score = 29.8 bits (65), Expect = 3.2, Method: Composition-based stats. Identities = 13/53 (24%), Positives = 17/53 (32%), Gaps = 6/53 (11%) Query: 179 ARQYGTSWYHSHFSAQYG------NGVVGTIQINGPASLPYDIDLGVFPITDY 225 A W+H H S + G G+ + S P D L V D Sbjct: 126 ADPTSERWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDK 178 >2CAK-A nrPDB Length = 154 Score = 29.4 bits (64), Expect = 4.2, Method: Composition-based stats. Identities = 10/50 (20%), Positives = 15/50 (30%), Gaps = 1/50 (2%) Query: 158 ANGVTECPIPPKGGQRTYRWR-ARQYGTSWYHSHFSAQYGNGVVGTIQIN 206 G P+P G + GT +Y G+ G I + Sbjct: 105 VAGTGFSPVPKDGKFGYTNFTWHPTAGTYYYVCQIPGHAATGMFGKIIVK 154 >5B5M-H nrPDB Length = 259 Score = 29.0 bits (63), Expect = 5.8, Method: Composition-based stats. Identities = 19/112 (16%), Positives = 29/112 (25%), Gaps = 3/112 (2%) Query: 350 GSLNPHPAAIFHYAGAPGGLPTDEGTPPVDHQCLDTLDVRPVVPRSVP---VNSFVKRPD 406 L + + G P E V+ P+VP P PD Sbjct: 59 PDLPDPKTFVLPHNGGTVVAPRVEAPVAVNATPFSPAPGSPLVPNGDPMLSGFGPAASPD 118 Query: 407 NTLPVALDLTGTPLFVWKVNGSDINVDWGKPIIDYILTGNTSYPVSDNIVQV 458 L G P V + ++ G P + V+ + V Sbjct: 119 RPKHCDLTFEGLPKIVPMRVAKEFSIAEGDPDPRGMTVVGLDGEVAGTVSDV 170 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.307 0.120 0.346 Lambda K H 0.267 0.0368 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 24,843,963 Number of Sequences: 36641 Number of extensions: 1072938 Number of successful extensions: 3374 Number of sequences better than 10.0: 85 Number of HSP's better than 10.0 without gapping: 108 Number of HSP's successfully gapped in prelim test: 42 Number of HSP's that attempted gapping in prelim test: 2512 Number of HSP's gapped (non-prelim): 273 length of query: 623 length of database: 10,336,785 effective HSP length: 103 effective length of query: 520 effective length of database: 6,562,762 effective search space: 3412636240 effective search space used: 3412636240 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 62 (28.6 bits)