BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q6UWY2 (283 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 4Q7Y-A nrPDB 503 e-143 1FDP-A nrPDB 168 2e-42 5FCR-A nrPDB 160 4e-40 2ZKS-A nrPDB 158 2e-39 1EUF-A nrPDB 158 2e-39 3G01-A nrPDB 156 8e-39 1FI8-A nrPDB 149 2e-36 3BSQ-A nrPDB 144 4e-35 1MZD-A nrPDB 142 1e-34 1IAU-A nrPDB 142 1e-34 4AN7-A nrPDB 139 1e-33 3TK9-A nrPDB 138 3e-33 1NPM-A nrPDB 137 4e-33 4WWY-A nrPDB 135 2e-32 1ORF-A nrPDB 135 3e-32 5C67-A nrPDB 134 3e-32 1A0J-A nrPDB 134 4e-32 1NN6-A nrPDB 134 6e-32 5FXL-A nrPDB 132 1e-31 2TLD-E nrPDB 131 3e-31 1AE5-A nrPDB 131 4e-31 1UTJ-A nrPDB 131 4e-31 5ZFH-A nrPDB 130 9e-31 1FUJ-A nrPDB 130 9e-31 1F7Z-A nrPDB 128 3e-30 1KYN-A nrPDB 127 4e-30 1PPF-E nrPDB 127 7e-30 5MS3-A nrPDB 126 1e-29 3RP2-A nrPDB 124 4e-29 2RDL-A nrPDB 124 5e-29 1ELT-A nrPDB 122 2e-28 2BDH-A nrPDB 120 4e-28 2V35-A nrPDB 120 6e-28 3QUM-P nrPDB 119 1e-27 2PSX-A nrPDB 119 2e-27 1BRU-P nrPDB 118 3e-27 1TON-A nrPDB 117 5e-27 1FIZ-A nrPDB 115 2e-26 6QHB-A nrPDB 115 2e-26 2EEK-A nrPDB 114 6e-26 1FIW-A nrPDB 113 9e-26 4NFE-A nrPDB 113 9e-26 1FON-A nrPDB 111 3e-25 1SGF-G nrPDB 111 3e-25 5LPF-A nrPDB 108 2e-24 1P57-B nrPDB 108 3e-24 3T2N-A nrPDB 107 4e-24 1SPJ-A nrPDB 107 4e-24 1GVZ-A nrPDB 107 5e-24 1YC0-A nrPDB 107 6e-24 2R0L-A nrPDB 106 9e-24 1AO5-A nrPDB 106 9e-24 3W94-A nrPDB 106 1e-23 1SGF-A nrPDB 105 2e-23 1LTO-A nrPDB 104 4e-23 2AIQ-A nrPDB 104 5e-23 1PYT-D nrPDB 103 6e-23 1BDA-A nrPDB 103 7e-23 2CGA-A nrPDB 103 8e-23 1AZZ-A nrPDB 103 1e-22 4MPW-A nrPDB 102 2e-22 3E0N-B nrPDB 102 3e-22 4XDE-A nrPDB 100 1e-21 5UGG-A nrPDB 99 2e-21 4H4F-A nrPDB 99 2e-21 4Z6A-H nrPDB 99 3e-21 4DUR-A nrPDB 98 3e-21 4IGD-A nrPDB 98 5e-21 1FXY-A nrPDB 98 5e-21 4GSO-A nrPDB 97 7e-21 3DFJ-A nrPDB 97 8e-21 1A5I-A nrPDB 96 1e-20 1EKB-B nrPDB 96 1e-20 4DGJ-A nrPDB 96 2e-20 4DJZ-B nrPDB 94 4e-20 2OQ5-A nrPDB 94 6e-20 5LHN-A nrPDB 93 1e-19 1SC8-U nrPDB 91 5e-19 1SI5-H nrPDB 91 5e-19 6AOD-C nrPDB 91 6e-19 5TJX-A nrPDB 90 9e-19 2F83-A nrPDB 89 2e-18 5XW8-A nrPDB 89 2e-18 4LK4-A nrPDB 88 4e-18 2ASU-B nrPDB 88 4e-18 2F91-A nrPDB 88 5e-18 5GVT-A nrPDB 87 1e-17 5KWM-A nrPDB 86 2e-17 1YM0-A nrPDB 86 2e-17 5XRF-A nrPDB 85 3e-17 1EQ9-A nrPDB 85 3e-17 1BQY-A nrPDB 85 4e-17 2XXL-A nrPDB 84 7e-17 6I44-A nrPDB 84 8e-17 1OP0-A nrPDB 82 2e-16 1M9U-A nrPDB 79 2e-15 1PQ7-A nrPDB 79 2e-15 3F6U-H nrPDB 78 5e-15 3S9B-A nrPDB 78 5e-15 2OCV-B nrPDB 77 9e-15 3S69-A nrPDB 77 1e-14 1ZJK-A nrPDB 76 2e-14 1MKW-K nrPDB 76 2e-14 1ETT-H nrPDB 75 2e-14 6BQM-A nrPDB 75 3e-14 1Q3X-A nrPDB 75 4e-14 2HLC-A nrPDB 74 5e-14 3P8G-A nrPDB 73 1e-13 2PKA-B nrPDB 72 2e-13 2OLG-A nrPDB 72 2e-13 5O32-I nrPDB 71 4e-13 3LC3-A nrPDB 71 5e-13 4FXG-H nrPDB 71 5e-13 1VR1-H nrPDB 71 6e-13 4E7N-A nrPDB 70 7e-13 3NXP-A nrPDB 69 2e-12 1X7A-C nrPDB 69 2e-12 4NZQ-A nrPDB 69 2e-12 3K65-B nrPDB 69 3e-12 1C5M-D nrPDB 69 3e-12 2XRC-A nrPDB 68 4e-12 3VGC-B nrPDB 68 4e-12 5TO3-B nrPDB 67 7e-12 2B9L-A nrPDB 65 2e-11 1KIG-H nrPDB 65 3e-11 3I77-A nrPDB 65 4e-11 4IW4-E nrPDB 65 4e-11 2JET-B nrPDB 64 1e-10 3H7O-A nrPDB 62 2e-10 3BEU-A nrPDB 62 3e-10 4KKD-A nrPDB 62 4e-10 1AKS-B nrPDB 59 3e-09 1GPZ-A nrPDB 56 2e-08 2QY0-B nrPDB 55 3e-08 2FMJ-A nrPDB 55 4e-08 2KAI-A nrPDB 54 6e-08 1MD7-A nrPDB 54 8e-08 3H7T-A nrPDB 53 2e-07 5UBM-A nrPDB 50 1e-06 4BXW-A nrPDB 50 1e-06 1ELV-A nrPDB 50 1e-06 1EPT-B nrPDB 49 2e-06 4J1Y-A nrPDB 49 3e-06 1BBR-H nrPDB 49 4e-06 1RIW-B nrPDB 48 4e-06 2JET-C nrPDB 46 2e-05 3RU4-E nrPDB 45 3e-05 1BBR-E nrPDB 39 0.002 4WJG-C nrPDB 37 0.011 4X0L-C nrPDB 37 0.011 2OK5-A nrPDB 37 0.013 2WIN-I nrPDB 37 0.014 1DLE-A nrPDB 37 0.014 2HNT-F nrPDB 35 0.047 2I6S-A nrPDB 33 0.13 4KQQ-A nrPDB 31 0.78 2HNT-C nrPDB 30 1.3 6DCR-A nrPDB 29 2.2 2DWN-A nrPDB 28 3.0 3F1S-B nrPDB 28 4.3 3H5C-B nrPDB 28 4.5 >4Q7Y-A nrPDB Length = 250 Score = 503 bits (1296), Expect = e-143, Method: Compositional matrix adjust. Identities = 249/250 (99%), Positives = 249/250 (99%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVL 93 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVL Sbjct: 1 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVL 60 Query: 94 STAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARPPTA 153 STAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLR PGRRARPPTA Sbjct: 61 STAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRLPGRRARPPTA 120 Query: 154 GTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWKGHLTLTMLCTRSGDSHRRGF 213 GTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWKGHLTLTMLCTRSGDSHRRGF Sbjct: 121 GTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWKGHLTLTMLCTRSGDSHRRGF 180 Query: 214 CSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVRRSSPQPGPLP 273 CSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVRRSSPQPGPLP Sbjct: 181 CSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVRRSSPQPGPLP 240 Query: 274 GTTRPPGEAA 283 GTTRPPGEAA Sbjct: 241 GTTRPPGEAA 250 >1FDP-A nrPDB Length = 235 Score = 168 bits (426), Expect = 2e-42, Method: Compositional matrix adjust. Identities = 100/240 (41%), Positives = 135/240 (56%), Gaps = 10/240 (4%) Query: 25 PPAGSWGAQIIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTG 84 PP G +I+GG E H+RPYMASV+ G H CGG L+ +WV+SAAHC Sbjct: 3 PPRG----RILGGREAEAHARPYMASVQLNGAHLCGGVLVAEQWVLSAAHCLEDAADGKV 58 Query: 85 LVVLGAHVLSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPP 144 V+LGAH LS EP+++++ + HPD P T +D+ LL+L+ A LGPAV L P Sbjct: 59 QVLLGAHSLSQPEPSKRLYDVLRAVPHPDSQPDTIDHDLLLLQLSEKATLGPAVRPL-PW 117 Query: 145 GRRARPPTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCN--SSWKGHLTLTMLC 202 R R GT C VAGWG V+ P L + VLD CN + G +T ++C Sbjct: 118 QRVDRDVAPGTLCDVAGWGIVNHAGRRPDSLQHVLLPVLDRATCNRRTHHDGAITERLMC 177 Query: 203 TRSGDSHRRGFCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVV 262 +S+RR C DSGGPLVC G+V+ CG+ K P +YT+V+++ AWI V+ Sbjct: 178 A---ESNRRDSCKGDSGGPLVCGGVLEGVVTSGSRVCGNRKKPGIYTRVASYAAWIDSVL 234 >5FCR-A nrPDB Length = 234 Score = 160 bits (406), Expect = 4e-40, Method: Compositional matrix adjust. Identities = 91/233 (39%), Positives = 133/233 (57%), Gaps = 7/233 (3%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSH-RDLRTGLVVLGAHV 92 I+GG E H+RPYMASV+ G H CGG LL +WV+SAAHC D + V+LGAH Sbjct: 1 ILGGQEAAAHARPYMASVQVNGTHVCGGTLLDEQWVLSAAHCMDGVTDDDSVQVLLGAHS 60 Query: 93 LSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARPPT 152 LS EP ++ + + ++ HP P + +D+ L +L+ +A LGP V L P + Sbjct: 61 LSAPEPYKRWYDVQSVVPHPGSRPDSLEDDLILFKLSQNASLGPHVRPL-PLQYEDKEVE 119 Query: 153 AGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCN--SSWKGHLTLTMLCTRSGDSHR 210 GT C VAGWG V+ P L + +V +++ CN + G +T+ M+C +S+R Sbjct: 120 PGTLCDVAGWGVVTHAGRRPDVLHQLRVSIMNRTTCNLRTYHDGVVTINMMC---AESNR 176 Query: 211 RGFCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVR 263 R C DSG PLVC + G+V++ CG+ K P VYT+VS++ WI ++ Sbjct: 177 RDTCRGDSGSPLVCGDAVEGVVTWGSRVCGNGKKPGVYTRVSSYRMWIENITN 229 >2ZKS-A nrPDB Length = 240 Score = 158 bits (400), Expect = 2e-39, Method: Compositional matrix adjust. Identities = 102/238 (42%), Positives = 135/238 (56%), Gaps = 11/238 (4%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVL 93 IIGG EV PHSRPYMAS++ G H CGG L+ +WV++AAHC + R + L VLG H L Sbjct: 1 IIGGREVIPHSRPYMASLQRNGSHLCGGVLVHPKWVLTAAHCLAQRMAQLRL-VLGLHTL 59 Query: 94 STAEPTQQVFGIDALTTHPDYHPM-THANDICLLRLNGSAVLGPAVGLLRPPGRRARPPT 152 + T F I A HP Y P+ ND+ LL+L+G + L P +R + Sbjct: 60 DSPGLT---FHIKAAIQHPRYKPVPALENDLALLQLDGKVKPSRTIRPLALPSKR-QVVA 115 Query: 153 AGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSS--WKGHLTLTMLCTRSGDSHR 210 AGTRC +AGWG L L E ++VLD +CN+S W G L+ +M+C + DS Sbjct: 116 AGTRCSMAGWGLTHQGGRLSRVLRELDLQVLDTRMCNNSRFWNGSLSPSMVCL-AADSKD 174 Query: 211 RGFCSADSGGPLVC-RNRA-HGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVRRSS 266 + C DSGGPLVC + R G++SFS C D P V T V+ +V+WI V RS+ Sbjct: 175 QAPCKGDSGGPLVCGKGRVLAGVLSFSSRVCTDIFKPPVATAVAPYVSWIRKVTGRSA 232 >1EUF-A nrPDB Length = 227 Score = 158 bits (400), Expect = 2e-39, Method: Compositional matrix adjust. Identities = 98/235 (41%), Positives = 128/235 (54%), Gaps = 14/235 (5%) Query: 34 IIGGHEVTPHSRPYMASVRF---GGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGA 90 IIGGHE PHSRPYMA + F G H CGGFL+R +V++AAHC + V LGA Sbjct: 1 IIGGHEAKPHSRPYMAFLLFKTSGKSHICGGFLVREDFVLTAAHCLGS----SINVTLGA 56 Query: 91 HVLSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARP 150 H + E TQQV + HPDY+ T ANDI LL+L A + V + P R Sbjct: 57 HNIMERERTQQVIPVRRPIPHPDYNDETLANDIMLLKLTRKADITDKVSPINLP-RSLAE 115 Query: 151 PTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWKGHLTLTMLCTRSGD-SH 209 G C VAGWG + L E + V + C + +K ++ T +C +GD S Sbjct: 116 VKPGMMCSVAGWGRLGVNMPSTDKLQEVDLEVQSEEKCIARFKNYIPFTQIC--AGDPSK 173 Query: 210 RRGFCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVRR 264 R+ S DSGGPLVC A G+VS+ D TPDVYT++S+F++WI +RR Sbjct: 174 RKNSFSGDSGGPLVCNGVAQGIVSYGR---NDGTTPDVYTRISSFLSWIHSTMRR 225 >3G01-A nrPDB Length = 227 Score = 156 bits (395), Expect = 8e-39, Method: Compositional matrix adjust. Identities = 97/236 (41%), Positives = 129/236 (54%), Gaps = 16/236 (6%) Query: 34 IIGGHEVTPHSRPYMASVRF----GGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLG 89 IIGG+E++PHSRPYMA F G + CGGFL+R ++V++AAHC R+ V LG Sbjct: 1 IIGGNEISPHSRPYMAYYEFLKVGGKKMFCGGFLVRDKFVLTAAHCKG----RSMTVTLG 56 Query: 90 AHVLSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRAR 149 AH + E TQQ+ + HPDY+P +NDI LL+L +A AV L P R A Sbjct: 57 AHNIKAKEETQQIIPVAKAIPHPDYNPDDRSNDIMLLKLVRNAKRTRAVRPLNLPRRNAH 116 Query: 150 PPTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWKGHLT-LTMLCTRSGDS 208 G C VAGWG V+ E P L E K+ V VC S ++ +C GDS Sbjct: 117 -VKPGDECYVAGWGKVTPDGEFPKTLHEVKLTVQKDQVCESQFQSSYNRANEICV--GDS 173 Query: 209 HRRGFC-SADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVR 263 +G DSGGPLVC+ A G+VS+ D P V+T+V +FV+WI ++ Sbjct: 174 KIKGASFRGDSGGPLVCKRAAAGIVSYGQT---DGSAPQVFTRVLSFVSWIKKTMK 226 >1FI8-A nrPDB Length = 228 Score = 149 bits (375), Expect = 2e-36, Method: Compositional matrix adjust. Identities = 90/238 (37%), Positives = 124/238 (52%), Gaps = 16/238 (6%) Query: 34 IIGGHEVTPHSRPYMASVR----FGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLG 89 IIGGHE PHSRPYMA ++ + G CGGFL+R +V++AAHC + V LG Sbjct: 1 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKIQ----VTLG 56 Query: 90 AHVLSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRAR 149 AH + E QQ+ + + HP Y+ T +NDI LL+L A AV L P RR Sbjct: 57 AHNIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLP-RRNV 115 Query: 150 PPTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWKGHL-TLTMLCTRSGDS 208 G C VAGWG + + L E ++ V + C S K + +C +GD Sbjct: 116 KVKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEIC--AGDP 173 Query: 209 H-RRGFCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVRRS 265 +R DSGGPLVC+ A G+VS+ D TP +T+VS F++WI +++S Sbjct: 174 KIKRASFRGDSGGPLVCKKVAAGIVSYGQ---NDGSTPRAFTKVSTFLSWIKKTMKKS 228 >3BSQ-A nrPDB Length = 227 Score = 144 bits (363), Expect = 4e-35, Method: Compositional matrix adjust. Identities = 89/231 (38%), Positives = 116/231 (50%), Gaps = 11/231 (4%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVL 93 II G S P+ ++ G Q HCGG L+ RWV++AAHC + V LG+ L Sbjct: 1 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHC----KMNEYTVHLGSDTL 56 Query: 94 STAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARPPTA 153 + Q HP Y TH ND+ L++LN A L V +R P R PP Sbjct: 57 --GDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSR-CEPP-- 111 Query: 154 GTRCRVAGWGFVSDFE-ELPPGLMEAKVRVLDPDVCNSSWKGHLTLTMLCTRSGDSHRRG 212 GT C V+GWG + + P LM V+++ P C +K L +MLC DS ++ Sbjct: 112 GTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDS-KKN 170 Query: 213 FCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVR 263 C+ DSGGPLVCR GLVS+ CG P P VYTQV F WI D ++ Sbjct: 171 ACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMK 221 >1MZD-A nrPDB Length = 240 Score = 142 bits (359), Expect = 1e-34, Method: Compositional matrix adjust. Identities = 90/235 (38%), Positives = 131/235 (55%), Gaps = 15/235 (6%) Query: 33 QIIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHC-FSHRDLRTGLVVLGAH 91 +IIGG EV+PHSRP+MAS+++GG H CGG L+ +WV++AAHC + ++ VVLGAH Sbjct: 2 EIIGGKEVSPHSRPFMASIQYGGHHVCGGVLIDPQWVLTAAHCQYRFTKGQSPTVVLGAH 61 Query: 92 VLSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARPP 151 LS E ++Q I +NDI L++L +A L V +L R Sbjct: 62 SLSKNEASKQTLEIKKFIPFSRVTSDPQSNDIMLVKLQTAAKLNKHVKMLHI--RSKTSL 119 Query: 152 TAGTRCRVAGWGFVSDFEELPPG--LMEAKVRVLDPDVCNSS--WKGH--LTLTMLCTRS 205 +GT+C+V GWG +D + L P L E V VL +CNS + G +T M+C + Sbjct: 120 RSGTKCKVTGWG-ATDPDSLRPSDTLREVTVTVLSRKLCNSQSYYNGDPFITKDMVC--A 176 Query: 206 GDSH-RRGFCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVS-AFVAWI 258 GD+ ++ C D+GGPL+C+ H +VS G CG P +YT ++ + WI Sbjct: 177 GDAKGQKDSCKGDAGGPLICKGVFHAIVS-GGHECGVATKPGIYTLLTKKYQTWI 230 >1IAU-A nrPDB Length = 227 Score = 142 bits (359), Expect = 1e-34, Method: Compositional matrix adjust. Identities = 94/235 (40%), Positives = 123/235 (52%), Gaps = 13/235 (5%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQH---HCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGA 90 IIGGHE PHSRPYMA + Q CGGFL+R +V++AAHC+ + V LGA Sbjct: 1 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWG----SSINVTLGA 56 Query: 91 HVLSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARP 150 H + EPTQQ + HP Y+P +NDI LL+L A AV LR P +A+ Sbjct: 57 HNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQ- 115 Query: 151 PTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWKGHLTLTM-LCTRSGDSH 209 G C VAGWG + + L E K+ V + C S + + T+ LC + Sbjct: 116 VKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIK 175 Query: 210 RRGFCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVRR 264 + F DSGGPLVC A G+VS+ G G P P T+VS+FV WI ++R Sbjct: 176 KTSF-KGDSGGPLVCNKVAQGIVSY-GRNNGMP--PRACTKVSSFVHWIKKTMKR 226 >4AN7-A nrPDB Length = 231 Score = 139 bits (350), Expect = 1e-33, Method: Compositional matrix adjust. Identities = 82/231 (35%), Positives = 117/231 (50%), Gaps = 11/231 (4%) Query: 33 QIIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHV 92 +I+GG+ +S PY S+ G H CGG L+ ++WVVSAAHC+ R V LG H Sbjct: 8 KIVGGYTCAANSIPYQVSLN-SGSHFCGGSLINSQWVVSAAHCYKSRI----QVRLGEHN 62 Query: 93 LSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARPPT 152 + E +Q + THP+++ T NDI L++L+ A L V + P A Sbjct: 63 IDVLEGNEQFINAAKIITHPNFNGNTLDNDIMLIKLSSPATLNSRVATVSLPRSCA---A 119 Query: 153 AGTRCRVAGWGFVSDFEELPPGLMEA-KVRVLDPDVCNSSWKGHLTLTMLCTRSGDSHRR 211 AGT C ++GWG P L++ K VL C SS+ G +T M+C + + Sbjct: 120 AGTECLISGWGNTKSSGSSYPSLLQCLKAPVLSDSSCKSSYPGQITGNMICVGFLEGGKD 179 Query: 212 GFCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVV 262 C DSGGP+VC + G+VS+ G C P VYT+V +V WI + Sbjct: 180 S-CQGDSGGPVVCNGQLQGIVSW-GYGCAQKNKPGVYTKVCNYVNWIQQTI 228 >3TK9-A nrPDB Length = 226 Score = 138 bits (347), Expect = 3e-33, Method: Compositional matrix adjust. Identities = 93/235 (39%), Positives = 124/235 (52%), Gaps = 14/235 (5%) Query: 34 IIGGHEVTPHSRPYMASVRF---GGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGA 90 IIGGHE PHSRPYMA V+F + CGG L+R +V++AAHC + V LGA Sbjct: 1 IIGGHEAKPHSRPYMAFVQFLQEKSRKRCGGILVRKDFVLTAAHCQGS----SINVTLGA 56 Query: 91 HVLSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARP 150 H + E TQQ + HP Y+P +N+I LL+L A AV LR P +A+ Sbjct: 57 HNIKEQERTQQFIPVKRPIPHPAYNPKNFSNNIMLLQLERKAKWTTAVRPLRLPSSKAQ- 115 Query: 151 PTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWKGHLT-LTMLCTRSGDSH 209 G C VAGWG+VS L L E + V C + G+ + T +C Sbjct: 116 VKPGQLCSVAGWGYVS-MSTLATTLQEVLLTVQKDCQCERLFHGNYSRATEICVGDPKKT 174 Query: 210 RRGFCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVRR 264 + GF DSGGPLVC++ A G++S+ G G P P VY +VS F+ WI ++R Sbjct: 175 QTGF-KGDSGGPLVCKDVAQGILSY-GNKKGTP--PGVYIKVSHFLPWIKRTMKR 225 >1NPM-A nrPDB Length = 225 Score = 137 bits (346), Expect = 4e-33, Method: Compositional matrix adjust. Identities = 82/229 (35%), Positives = 120/229 (52%), Gaps = 13/229 (5%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVL 93 I+ G E PHS+P+ A++ G + CGG L+ RWV++AAHC + V LG H L Sbjct: 1 ILEGRECIPHSQPWQAALFQGERLICGGVLVGDRWVLTAAHCKKQK----YSVRLGDHSL 56 Query: 94 STAEPTQQVFGIDALTTHPDYH---PMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARP 150 + + +Q + HP Y+ P H++DI L+RL SA LG V +P Sbjct: 57 QSRDQPEQEIQVAQSIQHPCYNNSNPEDHSHDIMLIRLQNSANLGDKV---KPVQLANLC 113 Query: 151 PTAGTRCRVAGWGFV-SDFEELPPGLMEAKVRVLDPDVCNSSWKGHLTLTMLCTRSGDSH 209 P G +C ++GWG V S E P L A+V++ + C ++ G +T M+C +G S+ Sbjct: 114 PKVGQKCIISGWGTVTSPQENFPNTLNCAEVKIYSQNKCERAYPGKITEGMVC--AGSSN 171 Query: 210 RRGFCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWI 258 C DSGGPLVC G+ S+ CG P+ P VYT++ + WI Sbjct: 172 GADTCQGDSGGPLVCDGMLQGITSWGSDPCGKPEKPGVYTKICRYTTWI 220 >4WWY-A nrPDB Length = 224 Score = 135 bits (340), Expect = 2e-32, Method: Compositional matrix adjust. Identities = 81/234 (34%), Positives = 114/234 (48%), Gaps = 11/234 (4%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVL 93 I+GG+ +S PY S+ G H CGG L+ +WVVSA HC+ R V LG H + Sbjct: 1 IVGGYNCEENSVPYQVSLN-SGYHFCGGSLINEQWVVSAGHCYKSRI----QVRLGEHNI 55 Query: 94 STAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARPPTA 153 E +Q + HP Y T NDI L++L+ AV+ V + P PP Sbjct: 56 EVLEGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVINAHVSTISLP---TAPPAT 112 Query: 154 GTRCRVAGWGFV-SDFEELPPGLMEAKVRVLDPDVCNSSWKGHLTLTMLCTRSGDSHRRG 212 GT+C ++GWG S + P L VL C +S+ G +T M C + + Sbjct: 113 GTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKITSNMFCVGFLEGGKDS 172 Query: 213 FCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVRRSS 266 C DSGGP+VC + G+VS+ G C P VYT+V +V WI + + +S Sbjct: 173 -CQRDSGGPVVCNGQLQGVVSW-GDGCAQKNKPGVYTKVYNYVKWIKNTIAANS 224 >1ORF-A nrPDB Length = 234 Score = 135 bits (339), Expect = 3e-32, Method: Compositional matrix adjust. Identities = 84/237 (35%), Positives = 125/237 (52%), Gaps = 13/237 (5%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVL 93 IIGG+EVTPHSRPYM + + C G L+ WV++AAHC ++ + V+LGAH + Sbjct: 1 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKRSQ---VILGAHSI 57 Query: 94 STAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARPPTA 153 + EPT+Q+ + +P Y P T D+ LL+L A + V +L P ++ Sbjct: 58 TREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLTEKAKINKYVTILHLP-KKGDDVKP 116 Query: 154 GTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNS----SWKGHLTLTMLCTRSGDSH 209 GT C+VAGWG + L E ++ ++D VCN ++ + + M+C S Sbjct: 117 GTMCQVAGWGRTHNSASWSDTLREVEITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGG 176 Query: 210 RRGFCSADSGGPLVCRNRAHGLVSFSGLW--CGDPKTPDVYTQVS-AFVAWIWDVVR 263 R C+ DSG PL+C G+ SF GL CGDP+ P VY +S + WI ++ Sbjct: 177 RDS-CNGDSGSPLLCEGVFRGVTSF-GLENKCGDPRGPGVYILLSKKHLNWIIMTIK 231 >5C67-A nrPDB Length = 224 Score = 134 bits (338), Expect = 3e-32, Method: Compositional matrix adjust. Identities = 83/234 (35%), Positives = 117/234 (50%), Gaps = 11/234 (4%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVL 93 I+GG+ +S PY S+ G H CGG L+ +WVVSAAHC+ R V LG H + Sbjct: 1 IVGGYTCEENSLPYQVSLN-SGSHFCGGSLISEQWVVSAAHCYKTRI----QVRLGEHNI 55 Query: 94 STAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARPPTA 153 E +Q + HP Y+ T NDI L++L+ AV+ V + P PP A Sbjct: 56 KVLEGNEQFINAAKIIRHPKYNRDTLDNDIMLIKLSSPAVINARVSTISLP---TAPPAA 112 Query: 154 GTRCRVAGWGFVSDF-EELPPGLMEAKVRVLDPDVCNSSWKGHLTLTMLCTRSGDSHRRG 212 GT C ++GWG F + P L VL C +S+ G +T +M C + + Sbjct: 113 GTECLISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKITNSMFCVGFLEGGKDS 172 Query: 213 FCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVRRSS 266 C D+GGP+VC + G+VS+ G C P VYT+V +V WI D + +S Sbjct: 173 -CQRDAGGPVVCNGQLQGVVSW-GHGCAWKNRPGVYTKVYNYVDWIKDTIAANS 224 >1A0J-A nrPDB Length = 223 Score = 134 bits (337), Expect = 4e-32, Method: Compositional matrix adjust. Identities = 82/226 (36%), Positives = 117/226 (51%), Gaps = 11/226 (4%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVL 93 I+GG+E +S Y AS++ G H CGG L+ + WVVSAAHC+ R V LG H + Sbjct: 1 IVGGYECRKNSASYQASLQ-SGYHFCGGSLISSTWVVSAAHCYKSRI----QVRLGEHNI 55 Query: 94 STAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARPPTA 153 + E T+Q + HP Y+ NDI L++L+ A L V + P A ++ Sbjct: 56 AVNEGTEQFIDSVKVIMHPSYNSRNLDNDIMLIKLSKPASLNSYVSTVALPSSCA---SS 112 Query: 154 GTRCRVAGWGFVS-DFEELPPGLMEAKVRVLDPDVCNSSWKGHLTLTMLCTRSGDSHRRG 212 GTRC V+GWG +S P L + +L CNS++ G +T M C + + Sbjct: 113 GTRCLVSGWGNLSGSSSNYPDTLRCLDLPILSSSSCNSAYPGQITSNMFCAGFMEGGKDS 172 Query: 213 FCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWI 258 C DSGGP+VC + G+VS+ G C P VYT+V + +WI Sbjct: 173 -CQGDSGGPVVCNGQLQGVVSW-GYGCAQRNKPGVYTKVCNYRSWI 216 >1NN6-A nrPDB Length = 228 Score = 134 bits (336), Expect = 6e-32, Method: Compositional matrix adjust. Identities = 89/235 (37%), Positives = 121/235 (51%), Gaps = 14/235 (5%) Query: 33 QIIGGHEVTPHSRPYMASVRF----GGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVL 88 +IIGG E PHSRPYMA + G CGGFL+R +V++AAHC R+ V L Sbjct: 2 EIIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAG----RSITVTL 57 Query: 89 GAHVLSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRA 148 GAH ++ E T Q + HP Y+ T +DI LL+L A L AVG L P + Sbjct: 58 GAHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFN 117 Query: 149 RPPTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWKGHLTLTMLCTRSGDS 208 P G CRVAGWG + L E K+R++DP C S ++ LC + Sbjct: 118 FVP-PGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQAC-SHFRDFDHNLQLCVGNPRK 175 Query: 209 HRRGFCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVR 263 + F DSGGPL+C A G+VS+ D K P V+T++S + WI +++ Sbjct: 176 TKSAF-KGDSGGPLLCAGVAQGIVSYGR---SDAKPPAVFTRISHYRPWINQILQ 226 >5FXL-A nrPDB Length = 246 Score = 132 bits (333), Expect = 1e-31, Method: Compositional matrix adjust. Identities = 79/232 (34%), Positives = 118/232 (50%), Gaps = 13/232 (5%) Query: 33 QIIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVV-LGAH 91 +I+GG+ ++ PY S+ G H CGG L+ ++WVVSAAHC+ ++G+ V LG Sbjct: 23 KIVGGYTCGANTVPYQVSLN-SGYHFCGGSLINSQWVVSAAHCY-----KSGIQVRLGED 76 Query: 92 VLSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARPP 151 ++ E +Q HP Y+ T NDI L++L +A L V + P A Sbjct: 77 NINVVEGNEQFISASKSIVHPSYNSNTLNNDIMLIKLKSAASLNSRVASISLPTSCA--- 133 Query: 152 TAGTRCRVAGWGFV-SDFEELPPGLMEAKVRVLDPDVCNSSWKGHLTLTMLCTRSGDSHR 210 +AGT+C ++GWG S P L K +L C S++ G +T M C + + Sbjct: 134 SAGTQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKSAYPGQITSNMFCAGYLEGGK 193 Query: 211 RGFCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVV 262 C DSGGP+VC + G+VS+ G C P VYT+V +V+WI + Sbjct: 194 DS-CQGDSGGPVVCSGKLQGIVSW-GSGCAQKNKPGVYTKVCNYVSWIKQTI 243 >2TLD-E nrPDB Length = 220 Score = 131 bits (330), Expect = 3e-31, Method: Compositional matrix adjust. Identities = 83/233 (35%), Positives = 119/233 (51%), Gaps = 20/233 (8%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVV-LGAHV 92 I+GG+ ++ PY S+ G H CGG L+ ++WVVSAAHC+ ++G+ V LG Sbjct: 1 IVGGYTCGANTVPYQVSLN-SGYHFCGGSLINSQWVVSAAHCY-----KSGIQVRLGEDN 54 Query: 93 LSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARPPT 152 ++ E +Q HP Y+ T NDI L++L +A L V + P A + Sbjct: 55 INVVEGNEQFISASKSIVHPSYNSNTLNNDIMLIKLKSAASLNSRVASISLPTSCA---S 111 Query: 153 AGTRCRVAGWGFV-SDFEELPPGLMEAKVRVLDPDVCNSSWKGHLTLTMLCT--RSGDSH 209 AGT+C ++GWG S P L K +L C S++ G +T M C GDS Sbjct: 112 AGTQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKSAYPGQITSNMFCAGLEGGDS- 170 Query: 210 RRGFCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVV 262 C DSGGP+VC + G+VS+ G C K P VYT+V +V+WI + Sbjct: 171 ----CQGDSGGPVVCSGKLQGIVSW-GSGCAKNK-PGVYTKVCNYVSWIKQTI 217 >1AE5-A nrPDB Length = 225 Score = 131 bits (329), Expect = 4e-31, Method: Compositional matrix adjust. Identities = 91/241 (37%), Positives = 129/241 (53%), Gaps = 20/241 (8%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVL 93 I+GG + P P++AS++ G+H CGG L+ AR+V++AA CF ++ VVLGA+ L Sbjct: 1 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDL 60 Query: 94 STAE-PTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARPPT 152 E ++Q F I +++ + Y P + ND+ LL+L+ A L +V +L P + A Sbjct: 61 RRRERQSRQTFSISSMSEN-GYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNA-TVE 118 Query: 153 AGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVC--NSSWKGHLTLTMLCTRSGDSHR 210 AGTRC+VAGWG L V V D C N+ G LT R Sbjct: 119 AGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCRPNNVCTGVLT-----------RR 167 Query: 211 RGFCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVRRSSPQPG 270 G C+ D G PLVC AHG+ SFS CG + PD +T+V+ F WI V+ ++P PG Sbjct: 168 GGICNGDGGTPLVCEGLAHGVASFSLGPCG--RGPDFFTRVALFRDWIDGVL--NNPGPG 223 Query: 271 P 271 P Sbjct: 224 P 224 >1UTJ-A nrPDB Length = 242 Score = 131 bits (329), Expect = 4e-31, Method: Compositional matrix adjust. Identities = 79/245 (32%), Positives = 118/245 (48%), Gaps = 12/245 (4%) Query: 15 VATALMLPVKPPAGSWGAQIIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAH 74 ++ +L + + +I+GG+E P+S+P+ S+ G H CGG L+ WVVSAAH Sbjct: 2 ISLVFVLLIGAAFATEDDKIVGGYECKPYSQPHQVSLN-SGYHFCGGSLVNENWVVSAAH 60 Query: 75 CFSHR-DLRTGLVVLGAHVLSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAV 133 C+ R ++R LG H + E ++Q + HP+Y NDI L++L+ A Sbjct: 61 CYKSRVEVR-----LGEHNIKVTEGSEQFISSSRVIRHPNYSSYNIDNDIMLIKLSKPAT 115 Query: 134 LGPAVGLLRPPGRRARPPTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWK 193 L V +P AGT C V+GWG L + +L CN+S+ Sbjct: 116 LNTYV---QPVALPTSCAPAGTMCTVSGWGNTMSSTADSNKLQCLNIPILSYSDCNNSYP 172 Query: 194 GHLTLTMLCTRSGDSHRRGFCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSA 253 G +T M C + + C DSGGP+VC G+VS+ G C +P P VY +V Sbjct: 173 GMITNAMFCAGYLEGGKDS-CQGDSGGPVVCNGELQGVVSW-GYGCAEPGNPGVYAKVCI 230 Query: 254 FVAWI 258 F W+ Sbjct: 231 FNDWL 235 >5ZFH-A nrPDB Length = 224 Score = 130 bits (326), Expect = 9e-31, Method: Compositional matrix adjust. Identities = 79/232 (34%), Positives = 114/232 (49%), Gaps = 13/232 (5%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHC-FSHRDLRTGLVVLGAHV 92 II G++ S P+ ++ G Q HCGG L+ WV++AAHC ++ G +G Sbjct: 1 IIDGYKCKEGSHPWQVALLKGNQLHCGGVLVDKYWVLTAAHCKMGQYQVQLGSDKIGDQS 60 Query: 93 LSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARPPT 152 + T+ HP Y TH NDI L+RL+ + V ++ P PP Sbjct: 61 AQKIKATKSF-------RHPGYSTKTHVNDIMLVRLDEPVKMSSKVEAVQLP-EHCEPP- 111 Query: 153 AGTRCRVAGWGFVSDFE-ELPPGLMEAKVRVLDPDVCNSSWKGHLTLTMLCTRSGDSHRR 211 GT C V+GWG + + P LM + V+++ C +K L TMLC DS + Sbjct: 112 -GTSCTVSGWGTTTSPDVTFPSDLMCSDVKLISSRECKKVYKDLLGKTMLCAGIPDS-KT 169 Query: 212 GFCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVR 263 C+ DSGGPLVC + GLVS+ CG P P VYTQV + W+ + ++ Sbjct: 170 NTCNGDSGGPLVCNDTLQGLVSWGTYPCGQPNDPGVYTQVCKYKRWVMETMK 221 >1FUJ-A nrPDB Length = 221 Score = 130 bits (326), Expect = 9e-31, Method: Compositional matrix adjust. Identities = 85/233 (36%), Positives = 121/233 (51%), Gaps = 15/233 (6%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQ---HHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGA 90 I+GGHE PHSRPYMAS++ G H CGG L+ +V++AAHC R VVLGA Sbjct: 1 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 60 Query: 91 HVLSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARP 150 H + T EPTQQ F + + + +Y NDI L++L+ A L +V ++ P ++ +P Sbjct: 61 HNVRTQEPTQQHFSVAQVFLN-NYDAENKLNDILLIQLSSPANLSASVATVQLP-QQDQP 118 Query: 151 PTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWKGHLTLTMLCTRSGDSHR 210 GT+C GWG V + PP + ++ V V + H T + R + Sbjct: 119 VPHGTQCLAMGWGRVGAHD--PPAQVLQELNV---TVVTFFCRPHNICTFVPRR-----K 168 Query: 211 RGFCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVR 263 G C DSGGPL+C G+ SF C PD +T+V+ +V WI +R Sbjct: 169 AGICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTLR 221 >1F7Z-A nrPDB Length = 233 Score = 128 bits (321), Expect = 3e-30, Method: Compositional matrix adjust. Identities = 80/230 (34%), Positives = 114/230 (49%), Gaps = 11/230 (4%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVL 93 I+GG+ +S PY S+ G H CGG L+ +WVVSAAHC+ R V LG H + Sbjct: 11 IVGGYTCQENSVPYQVSLN-SGYHFCGGSLINDQWVVSAAHCYKSRI----QVRLGEHNI 65 Query: 94 STAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARPPTA 153 + E +Q + HP++ T NDI L++L+ L V + P A A Sbjct: 66 NVLEGNEQFVNAAKIIKHPNFDRKTLNNDIMLIKLSSPVKLNARVATVALPSSCA---PA 122 Query: 154 GTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDV-CNSSWKGHLTLTMLCTRSGDSHRRG 212 GT+C ++GWG P L++ L P C +S+ G +T M+C + + Sbjct: 123 GTQCLISGWGNTLSSGVNEPDLLQCLDAPLLPQADCEASYPGKITDNMVCVGFLEGGKDS 182 Query: 213 FCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVV 262 C DSGGP+VC G+VS+ G C P P VYT+V +V WI D + Sbjct: 183 -CQGDSGGPVVCNGELQGIVSW-GYGCALPDNPGVYTKVCNYVDWIQDTI 230 >1KYN-A nrPDB Length = 235 Score = 127 bits (320), Expect = 4e-30, Method: Compositional matrix adjust. Identities = 92/234 (39%), Positives = 119/234 (50%), Gaps = 15/234 (6%) Query: 34 IIGGHEVTPHSRPYMASVRF---GGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGA 90 IIGG E PHSRPYMA ++ GQ CGGFL+R +V++AAHC+ V LGA Sbjct: 1 IIGGRESRPHSRPYMAYLQIQSPAGQSRCGGFLVREDFVLTAAHCWGS----NINVTLGA 56 Query: 91 HVLSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARP 150 H + E TQQ HP Y+ T NDI LL+L+ V + P R Sbjct: 57 HNIQRRENTQQHITARRAIRHPQYNQRTIQNDIMLLQLSRRVRRNRNVNPVALP-RAQEG 115 Query: 151 PTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWKGHLTLTMLCTRSGD-SH 209 GT C VAGWG VS L E ++RV C + + +C GD Sbjct: 116 LRPGTLCTVAGWGRVS-MRRGTDTLREVQLRVQRDRQCLRIFGSYDPRRQICV--GDRRE 172 Query: 210 RRGFCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVR 263 R+ DSGGPL+C N AHG+VS+ G G P P+V+T+VS+F+ WI +R Sbjct: 173 RKAAFKGDSGGPLLCNNVAHGIVSY-GKSSGVP--PEVFTRVSSFLPWIRTTMR 223 >1PPF-E nrPDB Length = 218 Score = 127 bits (318), Expect = 7e-30, Method: Compositional matrix adjust. Identities = 83/235 (35%), Positives = 117/235 (49%), Gaps = 22/235 (9%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVL 93 I+GG PH+ P+M S++ G H CG L+ +V+SAAHC ++ ++R VVLGAH L Sbjct: 1 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNL 60 Query: 94 STAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARPPTA 153 S EPT+QVF + + + Y P+ NDI +L+LNGSA + V + + P + R Sbjct: 61 SRREPTRQVFAVQRIFEN-GYDPVNLLNDIVILQLNGSATINANVQVAQLPA-QGRRLGN 118 Query: 154 GTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWKGHLTLTMLCTRSG-----DS 208 G +C GWG + + L E V V +T LC RS Sbjct: 119 GVQCLAMGWGLLGRNRGIASVLQELNVTV---------------VTSLCRRSNVCTLVRG 163 Query: 209 HRRGFCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVR 263 + G C DSG PLVC HG+ SF C PD + V+ FV WI +++ Sbjct: 164 RQAGVCFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQ 218 >5MS3-A nrPDB Length = 228 Score = 126 bits (316), Expect = 1e-29, Method: Compositional matrix adjust. Identities = 79/233 (33%), Positives = 115/233 (49%), Gaps = 13/233 (5%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVL 93 ++GGHE PHS+P+ A++ G Q CGG L+ WV++AAHC + V LG H L Sbjct: 1 VLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHCKKPK----YTVRLGDHSL 56 Query: 94 STAEPTQQVFGIDALTTHPDYHP---MTHANDICLLRLNGSAVLGPAVGLLRPPGRRARP 150 + +Q + HP Y+ H +D+ LL+L A LG V + +P Sbjct: 57 QNKDGPEQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQASLGSKVKPISLADHCTQP 116 Query: 151 PTAGTRCRVAGWGFV-SDFEELPPGLMEAKVRVLDPDVCNSSWKGHLTLTMLCTRSGDSH 209 G +C V+GWG V S E P L A+V++ C ++ G +T M+C +G S Sbjct: 117 ---GQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQITDGMVC--AGSSK 171 Query: 210 RRGFCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVV 262 C DSGGPLVC G+ S+ CG P VYT + ++ WI ++ Sbjct: 172 GADTCQGDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWIKKII 224 >3RP2-A nrPDB Length = 224 Score = 124 bits (311), Expect = 4e-29, Method: Compositional matrix adjust. Identities = 85/236 (36%), Positives = 120/236 (50%), Gaps = 18/236 (7%) Query: 34 IIGGHEVTPHSRPYMASVRF----GGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLG 89 IIGG E PHSRPYMA + G + CGGFL+ ++V++AAHC R V+LG Sbjct: 1 IIGGVESIPHSRPYMAHLDIVTEKGLRVICGGFLISRQFVLTAAHCKG----REITVILG 56 Query: 90 AHVLSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGL--LRPPGRR 147 AH + E TQQ ++ H Y+ + + +DI LL+L L PAV + L P Sbjct: 57 AHDVRKRESTQQKIKVEKQIIHESYNSVPNLHDIMLLKLEKKVELTPAVNVVPLPSPSDF 116 Query: 148 ARPPTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWKGHLTLTMLCTRSGD 207 P G C AGWG + L E ++R++D C ++ + +C S Sbjct: 117 IHP---GAMCWAAGWGKTGVRDPTSYTLREVELRIMDEKAC-VDYRYYEYKFQVCVGSPT 172 Query: 208 SHRRGFCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVR 263 + R F DSGGPL+C AHG+VS+ D K P ++T+VS +V WI V+ Sbjct: 173 TLRAAFM-GDSGGPLLCAGVAHGIVSYGH---PDAKPPAIFTRVSTYVPWINAVIN 224 >2RDL-A nrPDB Length = 226 Score = 124 bits (310), Expect = 5e-29, Method: Compositional matrix adjust. Identities = 84/236 (35%), Positives = 115/236 (48%), Gaps = 14/236 (5%) Query: 34 IIGGHEVTPHSRPYMASVRFGG-QHH---CGGFLLRARWVVSAAHCFSHRDLRTGLVVLG 89 IIGG E PH+RPYMA + ++H C GFL+R +V++AAHC R+ V+LG Sbjct: 1 IIGGTECRPHARPYMAYLEIVTPENHLSACSGFLIRRNFVMTAAHCAG----RSITVLLG 56 Query: 90 AHVLSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRAR 149 AH E T Q ++ HP Y NDI LL+L A L VG L P ++ Sbjct: 57 AHNKKVKEDTWQKLEVEKQFPHPKYDDRLVLNDIMLLKLKEKANLTLGVGTL-PISAKSN 115 Query: 150 PPTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWKGHLTLTMLCTRSGDSH 209 G CR GWG + E L E K+R+LDP C H LC + Sbjct: 116 SIPPGRVCRAVGWGRTNVNEPPSDTLQEVKMRILDPQACKHFEDFHQE-PQLCVGNPKKI 174 Query: 210 RRGFCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVRRS 265 R + DSGGPL+C A G+ S+ + K P V+T++S + WI ++R + Sbjct: 175 RNVY-KGDSGGPLLCAGIAQGIASYV---LRNAKPPSVFTRISHYRPWINKILREN 226 >1ELT-A nrPDB Length = 236 Score = 122 bits (306), Expect = 2e-28, Method: Compositional matrix adjust. Identities = 85/239 (35%), Positives = 121/239 (50%), Gaps = 21/239 (8%) Query: 34 IIGGHEVTPHSRPYMASVRFGG----QHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLG 89 ++GG P+S P+ S+++ H CGG L+R WV++AAHC RT VVLG Sbjct: 1 VVGGRVAQPNSWPWQISLQYKSGSSYYHTCGGSLIRQGWVMTAAHCVD--SARTWRVVLG 58 Query: 90 AHVLSTAEPTQQVFGIDALTTHPDYHPMTHAN--DICLLRLNGSAVLGPAVGLLR-PPGR 146 H L+T E +Q+ ++++ H ++ A DI LLRLN A L AV L PP Sbjct: 59 EHNLNTNEGKEQIMTVNSVFIHSGWNSDDVAGGYDIALLRLNTQASLNSAVQLAALPPSN 118 Query: 147 RARPPTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSS--WKGHLTLTMLCTR 204 + P C + GWG S L L +A + +D C+SS W + TM+C Sbjct: 119 QILPNN--NPCYITGWGKTSTGGPLSDSLKQAWLPSVDHATCSSSGWWGSTVKTTMVCAG 176 Query: 205 SGDSHRRGFCSADSGGPLVCR----NRAHGLVSF-SGLWCGDPKTPDVYTQVSAFVAWI 258 G C+ DSGGPL C+ HG+ SF S C K P V+T+VSA+++W+ Sbjct: 177 GG---ANSGCNGDSGGPLNCQVNGSYYVHGVTSFVSSSGCNASKKPTVFTRVSAYISWM 232 >2BDH-A nrPDB Length = 223 Score = 120 bits (302), Expect = 4e-28, Method: Compositional matrix adjust. Identities = 77/231 (33%), Positives = 116/231 (50%), Gaps = 10/231 (4%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVL 93 II G + +PHS+P+ A++ + C G L+ +WV+SAAHCF + + + LG H L Sbjct: 1 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQN----SYTIGLGLHSL 56 Query: 94 -STAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARPPT 152 + EP Q+ HP+Y+ AND+ L++L+ S + R ++ PT Sbjct: 57 EADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTI---RSISIASQCPT 113 Query: 153 AGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWKGHLTLTMLCTRSGDSHRRG 212 AG C V+GWG +++ +P L V V+ +VC+ + +M C G + Sbjct: 114 AGNSCLVSGWGLLAN-GRMPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGQDQKDS 172 Query: 213 FCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVR 263 C+ DSGGPL+C GLVSF CG P VYT + F WI V+ Sbjct: 173 -CNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQ 222 >2V35-A nrPDB Length = 240 Score = 120 bits (302), Expect = 6e-28, Method: Compositional matrix adjust. Identities = 85/242 (35%), Positives = 125/242 (51%), Gaps = 18/242 (7%) Query: 34 IIGGHEVTPHSRPYMASVRFGG----QHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLG 89 ++GG E +S P S+++ H CGG L+R WV++AAHC R+L T VV+G Sbjct: 1 VVGGTEAQRNSWPSQISLQYRSGSSWAHTCGGTLIRQNWVMTAAHCVD-REL-TFRVVVG 58 Query: 90 AHVLSTAEPTQQVFGIDALTTHPDYHP--MTHANDICLLRLNGSAVLGPAVGLLRPPGRR 147 H L+ + T+Q G+ + HP ++ + DI LLRL S L V L P R Sbjct: 59 EHNLNQNDGTEQYVGVQKIVVHPYWNTDDVAAGYDIALLRLAQSVTLNSYVQLGVLP-RA 117 Query: 148 ARPPTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSS--WKGHLTLTMLCTRS 205 + C + GWG +L L +A + +D +C+SS W + +M+C Sbjct: 118 GTILANNSPCYITGWGLTRTNGQLAQTLQQAYLPTVDYAICSSSSYWGSTVKNSMVCA-G 176 Query: 206 GDSHRRGFCSADSGGPLVC----RNRAHGLVSF-SGLWCGDPKTPDVYTQVSAFVAWIWD 260 GD R G C DSGGPL C + HG+ SF S L C + P V+T+VSA+++WI + Sbjct: 177 GDGVRSG-CQGDSGGPLHCLVNGQYAVHGVTSFVSRLGCNVTRKPTVFTRVSAYISWINN 235 Query: 261 VV 262 V+ Sbjct: 236 VI 237 >3QUM-P nrPDB Length = 237 Score = 119 bits (299), Expect = 1e-27, Method: Compositional matrix adjust. Identities = 81/241 (33%), Positives = 116/241 (48%), Gaps = 20/241 (8%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVL 93 I+GG E HS+P+ V G+ CGG L+ +WV++AAHC ++ +++LG H L Sbjct: 1 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNK----SVILLGRHSL 56 Query: 94 STAEPTQQVFGIDALTTHPDYHPMTHAN-----------DICLLRLNGSAVLGPAVGLLR 142 E T QVF + HP Y N D+ LLRL+ A L AV ++ Sbjct: 57 FHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMD 116 Query: 143 PPGRRARPPTAGTRCRVAGWGFVSDFEELPPGLME-AKVRVLDPDVCNSSWKGHLTLTML 201 P + P GT C +GWG + E L P ++ + V+ DVC +T ML Sbjct: 117 LPTQE---PALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFML 173 Query: 202 CTRSGDSHRRGFCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDV 261 C + + CS DSGGPLVC G+ S+ C P+ P +YT+V + WI D Sbjct: 174 CAGRW-TGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDT 232 Query: 262 V 262 + Sbjct: 233 I 233 >2PSX-A nrPDB Length = 227 Score = 119 bits (297), Expect = 2e-27, Method: Compositional matrix adjust. Identities = 78/236 (33%), Positives = 116/236 (49%), Gaps = 12/236 (5%) Query: 34 IIGGHEVTPHSRPYMASVRFG-GQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHV 92 II G + H++P+ A++ Q +CG L+ +W+++AAHC + V LG + Sbjct: 1 IINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRK----KVFRVRLGHYS 56 Query: 93 LS-TAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARPP 151 LS E QQ+F HP Y H+ND+ L++LN + P + RP + P Sbjct: 57 LSPVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRR--IRPTKDV-RPINVSSHCP 113 Query: 152 TAGTRCRVAGWGFVSDFE-ELPPGLMEAKVRVLDPDVCNSSWKGHLTLTMLCTRSGDSHR 210 +AGT+C V+GWG + P L + VL C ++ + TM C +GD Sbjct: 114 SAGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFC--AGDKAG 171 Query: 211 RGFCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVRRSS 266 R C DSGGP+VC GLVS+ C P P VYT + F WI + ++ +S Sbjct: 172 RDSCQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQANS 227 >1BRU-P nrPDB Length = 241 Score = 118 bits (295), Expect = 3e-27, Method: Compositional matrix adjust. Identities = 84/245 (34%), Positives = 120/245 (48%), Gaps = 17/245 (6%) Query: 34 IIGGHEVTPHSRPYMASVRF--GGQ--HHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLG 89 ++GG + P+S P+ S+++ GQ H CGG L+ WV++AAHC S RT VVLG Sbjct: 1 VVGGEDARPNSWPWQVSLQYDSSGQWRHTCGGTLVDQSWVLTAAHCISSS--RTYRVVLG 58 Query: 90 AHVLSTAEPTQQVFGIDALTTHPDYHP--MTHANDICLLRLNGSAVLGPAVGLLRPPGRR 147 H LST EP + L H D++ +++ NDI LL+L L + L P Sbjct: 59 RHSLSTNEPGSLAVKVSKLVVHQDWNSNQLSNGNDIALLKLASPVSLTDKIQLGCLPAAG 118 Query: 148 ARPPTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNS-SWKGHLTLTMLCTRSG 206 P C V GWG + P L + ++ V+D C+ W G T + G Sbjct: 119 TILPN-NYVCYVTGWGRLQTNGASPDILQQGQLLVVDYATCSKPGWWGSTVKTNMICAGG 177 Query: 207 DSHRRGFCSADSGGPLVCRN-----RAHGLVSF-SGLWCGDPKTPDVYTQVSAFVAWIWD 260 D C+ DSGGPL C+ + HG+VSF S L C P V+T+VS ++ WI Sbjct: 178 DGIISS-CNGDSGGPLNCQGANGQWQVHGIVSFGSSLGCNYYHKPSVFTRVSNYIDWINS 236 Query: 261 VVRRS 265 V+ + Sbjct: 237 VIANN 241 >1TON-A nrPDB Length = 235 Score = 117 bits (294), Expect = 5e-27, Method: Compositional matrix adjust. Identities = 73/244 (29%), Positives = 121/244 (49%), Gaps = 22/244 (9%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVL 93 I+GG++ +S+P+ +V ++ CGG L+ WV++AAHC+S+ V+LG + L Sbjct: 1 IVGGYKCEKNSQPWQVAVI--NEYLCGGVLIDPSWVITAAHCYSNN----YQVLLGRNNL 54 Query: 94 STAEPTQQVFGIDALTTHPDYHPMT-----------HANDICLLRLNGSAVLGPAVGLLR 142 EP Q + HPDY P+ H+ND+ LL L+ A + V ++ Sbjct: 55 FKDEPFAQRRLVRQSFRHPDYIPLIVTNDTEQPVHDHSNDLMLLHLSEPADITGGVKVID 114 Query: 143 PPGRRARPPTAGTRCRVAGWGFVSDFEELPP-GLMEAKVRVLDPDVCNSSWKGHLTLTML 201 P + P G+ C +GWG + E + L + +L + C ++K ++T ML Sbjct: 115 LPTKE---PKVGSTCLASGWGSTNPSEMVVSHDLQCVNIHLLSNEKCIETYKDNVTDVML 171 Query: 202 CTRSGDSHRRGFCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDV 261 C + + C+ DSGGPL+C G+ S C PKTP +Y ++ F +WI V Sbjct: 172 CAGEMEG-GKDTCAGDSGGPLICDGVLQGITSGGATPCAKPKTPAIYAKLIKFTSWIKKV 230 Query: 262 VRRS 265 ++ + Sbjct: 231 MKEN 234 >1FIZ-A nrPDB Length = 263 Score = 115 bits (289), Expect = 2e-26, Method: Compositional matrix adjust. Identities = 80/250 (32%), Positives = 125/250 (50%), Gaps = 31/250 (12%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQHH------CGGFLLRARWVVSAAHCFSHRDLRTGL-V 86 ++GG P + P+M S++ H+ CGG LL + WV++AAHCF ++ T + Sbjct: 1 VVGGMSAEPGAWPWMVSLQIFMYHNNRRYHTCGGILLNSHWVLTAAHCFKNKKKVTDWRL 60 Query: 87 VLGAHVLS------TAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGL 140 + GA+ + P Q+ F ++ + H Y NDI L+++ GP +G Sbjct: 61 IFGANEVVWGSNKPVKPPLQERF-VEEIIIHEKYVSGLEINDIALIKITPPVPCGPFIGP 119 Query: 141 LRPPGRRARPPTAGTRCRVAGWGFVSDF-EELPPGLMEAKVRVLDPDVCNSS--WKGHLT 197 P +A PP A C V GWG++ + P L EA+V ++D ++CNS+ + G + Sbjct: 120 GCLPQFKAGPPRAPQTCWVTGWGYLKEKGPRTSPTLQEARVALIDLELCNSTRWYNGRIR 179 Query: 198 LTMLCTRSGDSHRRG---FCSADSGGPLVCRNRAH------GLVSFSGLWCGDPKTPDVY 248 T +C + RG C DSGGPL+CR+RA G+ S+ G+ C K P VY Sbjct: 180 STNVCA----GYPRGKIDTCQGDSGGPLMCRDRAENTFVVVGITSW-GVGCARAKRPGVY 234 Query: 249 TQVSAFVAWI 258 T ++ WI Sbjct: 235 TSTWPYLNWI 244 >6QHB-A nrPDB Length = 223 Score = 115 bits (289), Expect = 2e-26, Method: Compositional matrix adjust. Identities = 74/220 (33%), Positives = 108/220 (49%), Gaps = 9/220 (4%) Query: 44 SRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVLSTAEPTQQVF 103 S PY A++ G CGG L+ WV++AAHC +L+ V LG H L E +Q+ Sbjct: 11 SHPYQAALYTSGHLLCGGVLIHPLWVLTAAHC-KKPNLQ---VFLGKHNLGQQESSQEQS 66 Query: 104 GIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARPPTAGTRCRVAGWG 163 + HPDY +H DI LLRL A L L++P T C + GWG Sbjct: 67 SVVRAVIHPDYDAASHDQDIMLLRLARPAKLSE---LIQPLPLERDCSAQTTSCHILGWG 123 Query: 164 FVSDFEELPPGLMEAKVRVLDPDVCNSSWKGHLTLTMLCTRSGDSHRRGFCSADSGGPLV 223 +D + P + A + ++ + C ++ G +T MLC + + + C DSGGPLV Sbjct: 124 KTAD-GDFPDTIQCAYIHLVSREECEHAYPGQITQNMLCA-GDEKYGKDSCQGDSGGPLV 181 Query: 224 CRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVR 263 C + GLVS+ + CG + P VYT V + WI ++ Sbjct: 182 CGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQKTIQ 221 >2EEK-A nrPDB Length = 220 Score = 114 bits (284), Expect = 6e-26, Method: Compositional matrix adjust. Identities = 77/229 (33%), Positives = 108/229 (47%), Gaps = 10/229 (4%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVL 93 I+GG+E T HS+ + S+ G H CGG L+ WVVSAAHC+ LR V LG H + Sbjct: 1 IVGGYECTKHSQAHQVSLN-SGYHFCGGSLVSKDWVVSAAHCYK-SVLR---VRLGEHHI 55 Query: 94 STAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARPPTA 153 E T+Q ++ HP+Y NDI L++L A L V + P A Sbjct: 56 RVNEGTEQYISSSSVIRHPNYSSYNINNDIMLIKLTKPATLNQYVHAVALPTECAADA-- 113 Query: 154 GTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWKGHLTLTMLCTRSGDSHRRGF 213 T C V+GWG L + +L C +S+ G +T +M C + + Sbjct: 114 -TMCTVSGWGNTMSSVADGDKLQCLSLPILSHADCANSYPGMITQSMFCAGYLEGGKDS- 171 Query: 214 CSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVV 262 C DSGGP+VC G+VS+ G C + P VY +V W+ D + Sbjct: 172 CQGDSGGPVVCNGVLQGVVSW-GYGCAERDHPGVYAKVCVLSGWVRDTM 219 >1FIW-A nrPDB Length = 290 Score = 113 bits (283), Expect = 9e-26, Method: Compositional matrix adjust. Identities = 78/246 (31%), Positives = 124/246 (50%), Gaps = 23/246 (9%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQHH------CGGFLLRARWVVSAAHCFSHRDLRTGL-V 86 IIGG + + P+M S++ H+ CGG LL ++W+++AAHCF + T + Sbjct: 1 IIGGQDAAHGAWPWMVSLQIFTYHNNRRYHVCGGSLLNSQWLLTAAHCFRIKKKVTDWRL 60 Query: 87 VLGAHVLS--TAEPTQ---QVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLL 141 + GA + T +P + Q ++ + H Y + ANDI L+++ G +G Sbjct: 61 IFGAKEVEWGTNKPVKPPLQERYVEKIIIHEKYSASSEANDIALMKITPPVTCGHFIGPG 120 Query: 142 RPPGRRARPPTAGTRCRVAGWGFVSD-FEELPPGLMEAKVRVLDPDVCNSS--WKGHLTL 198 P RA PP C VAGWGF+ + P L EA+V ++D +CNS+ + G + Sbjct: 121 CLPQFRAGPPRVPQTCWVAGWGFLQENARRTSPMLQEARVDLIDLGLCNSTRWYNGRIRS 180 Query: 199 TMLCTRSGDSHRRGFCSADSGGPLVCRNRAH------GLVSFSGLWCGDPKTPDVYTQVS 252 T +C + + C DSGGPL+C++ A G+ S+ G+ C K P VYT Sbjct: 181 TNVCAGYPEG-KIDTCQGDSGGPLMCKDSAENSYVVVGITSW-GVGCARAKRPGVYTSTW 238 Query: 253 AFVAWI 258 +++ WI Sbjct: 239 SYLNWI 244 >4NFE-A nrPDB Length = 237 Score = 113 bits (282), Expect = 9e-26, Method: Compositional matrix adjust. Identities = 80/241 (33%), Positives = 114/241 (47%), Gaps = 20/241 (8%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVL 93 I+GG E HS+P+ +V G HCGG L+ +WV++AAHC + V LG H L Sbjct: 1 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLK----KNSQVWLGRHNL 56 Query: 94 STAEPTQQVFGIDALTTHPDYHP--MTH---------ANDICLLRLNGSAVLGPAVGLLR 142 E T Q + HP Y+ + H ++D+ LLRL+ A + V +L Sbjct: 57 FEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVL- 115 Query: 143 PPGRRARPPTAGTRCRVAGWGFVSDFEEL-PPGLMEAKVRVLDPDVCNSSWKGHLTLTML 201 G + P GT C +GWG + E L P L + +L D+C ++ +T ML Sbjct: 116 --GLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFML 173 Query: 202 CTRSGDSHRRGFCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDV 261 C + C DSGGPLVC G+ S+ C P+ P VYT+V + WI D Sbjct: 174 CAGLWTG-GKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDT 232 Query: 262 V 262 + Sbjct: 233 I 233 >1FON-A nrPDB Length = 240 Score = 111 bits (278), Expect = 3e-25, Method: Compositional matrix adjust. Identities = 90/239 (37%), Positives = 124/239 (51%), Gaps = 24/239 (10%) Query: 37 GHEVTPHSRPYMASVRF---GGQHH-CGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHV 92 G + P+S + S+++ G HH CGG L+ WVV+A HC S RT VVLG + Sbjct: 2 GEDAVPYSWSWQVSLQYEKDGAFHHTCGGSLIAPDWVVTAGHCISTS--RTYQVVLGEYD 59 Query: 93 LSTAEPTQQVFGIDA--LTTHPDYHPMTHA--NDICLLRLNGSAVLGPAVGLLR-PPGRR 147 S E ++QV I+A L HP ++ A NDI L++L+ SA LG V L PP Sbjct: 60 RSVLEGSEQVIPINAGDLFVHPLWNSNCVACGNDIALVKLSRSAQLGDKVQLANLPPAGD 119 Query: 148 ARPPTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCN--SSWKGHLTLTMLCTRS 205 P A C ++GWG + LP L +A + +D + C+ W + TM+C Sbjct: 120 ILPNEA--PCYISGWGRLYTGGPLPDKLQQALLPTVDYEHCSQWDWWGITVKKTMVCA-G 176 Query: 206 GDSHRRGFCSADSGGPLVC-----RNRAHGLVSF-SGLWCGDPKTPDVYTQVSAFVAWI 258 GD+ R C+ DSGGPL C + HG+ SF S C K P V+T+VSAF+ WI Sbjct: 177 GDT--RSGCNGDSGGPLNCPAADGSWQVHGVTSFVSAFGCNTIKKPTVFTRVSAFIDWI 233 >1SGF-G nrPDB Length = 237 Score = 111 bits (278), Expect = 3e-25, Method: Compositional matrix adjust. Identities = 71/244 (29%), Positives = 116/244 (47%), Gaps = 20/244 (8%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVL 93 I+GG + +S+P+ +V Q+ CGG LL WV++AAHC+ V LG + L Sbjct: 1 IVGGFKCEKNSQPWHVAVYRYTQYLCGGVLLDPNWVLTAAHCYDDN----YKVWLGKNNL 56 Query: 94 STAEPTQQV-----------FGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLR 142 EP+ Q F + + H + ++ND+ LLRL+ A + V + Sbjct: 57 FKDEPSAQHRFVSKAIPHPGFNMSLMRKHIRFLEYDYSNDLMLLRLSKPADITDTV---K 113 Query: 143 PPGRRARPPTAGTRCRVAGWGFVSDFE-ELPPGLMEAKVRVLDPDVCNSSWKGHLTLTML 201 P P G+ C +GWG ++ + + L +++L + C + +T ML Sbjct: 114 PITLPTEEPKLGSTCLASGWGSITPTKFQFTDDLYCVNLKLLPNEDCAKAHIEKVTDAML 173 Query: 202 CTRSGDSHRRGFCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDV 261 C D + C DSGGPL+C G+ S+ CG+P P VYT+++ F +WI D Sbjct: 174 CAGEMDGGKDT-CKGDSGGPLICDGVLQGITSWGHTPCGEPDMPGVYTKLNKFTSWIKDT 232 Query: 262 VRRS 265 + ++ Sbjct: 233 MAKN 236 >5LPF-A nrPDB Length = 234 Score = 108 bits (271), Expect = 2e-24, Method: Compositional matrix adjust. Identities = 78/237 (32%), Positives = 117/237 (49%), Gaps = 31/237 (13%) Query: 44 SRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDL--RTG----LVVLGAHVLSTAE 97 S+P+ S+ G HC G L+ WV++AAHC ++ L R G L++ G + T Sbjct: 14 SQPWQVSLFNGLSFHCAGVLVDQSWVLTAAHC-GNKPLWARVGDDHLLLLQGEQLRRTTR 72 Query: 98 PTQQVFGIDALTTHPDYHP--------MTHANDICLLRLNGSAVLGPAVGLLRPPGRRAR 149 HP YH T +D+ LL+L VLGP V L+ P R A+ Sbjct: 73 SV----------VHPKYHQGSGPILPRRTDEHDLMLLKLARPVVLGPRVRALQLPYRCAQ 122 Query: 150 PPTAGTRCRVAGWGFVSDFE-ELPPGLMEAKVRVLDPDVCNSSWKGHLTLTMLCTRSGDS 208 P G +C+VAGWG + + GL + + +L P C + G +T M+C +G Sbjct: 123 P---GDQCQVAGWGTTAARRVKYNKGLTCSSITILSPKECEVFYPGVVTNNMIC--AGLD 177 Query: 209 HRRGFCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVRRS 265 + C +DSGGPLVC G++S+ CG + P VYTQ+ +++WI V+R + Sbjct: 178 RGQDPCQSDSGGPLVCDETLQGILSWGVYPCGSAQHPAVYTQICKYMSWINKVIRSN 234 >1P57-B nrPDB Length = 255 Score = 108 bits (270), Expect = 3e-24, Method: Compositional matrix adjust. Identities = 77/253 (30%), Positives = 115/253 (45%), Gaps = 19/253 (7%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVL 93 I+GG + + P+ S+R+ G H CGG LL WV++AAHCF R+ + A + Sbjct: 1 IVGGRDTSLGRWPWQVSLRYDGAHLCGGSLLSGDWVLTAAHCFPERNRVLSRWRVFAGAV 60 Query: 94 STAEPTQQVFGIDALTTHPDYHPM------THANDICLLRLNGSAVLGPAVGLLRPPGRR 147 + A P G+ A+ H Y P ++NDI L+ L+ L + + P Sbjct: 61 AQASPHGLQLGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLTEYIQPVCLPA-A 119 Query: 148 ARPPTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSS--WKGHLTLTMLCTRS 205 + G C V GWG + + L EA+V ++ DVCN + + + M C Sbjct: 120 GQALVDGKICTVTGWGNTQYYGQQAGVLQEARVPIISNDVCNGADFYGNQIKPKMFCAGY 179 Query: 206 GDSHRRGFCSADSGGPLVCRN--------RAHGLVSFSGLWCGDPKTPDVYTQVSAFVAW 257 + C DSGGP VC + R G+VS+ G C + P VYT+VS F W Sbjct: 180 PEGGIDA-CQGDSGGPFVCEDSISRTPRWRLCGIVSW-GTGCALAQKPGVYTKVSDFREW 237 Query: 258 IWDVVRRSSPQPG 270 I+ ++ S G Sbjct: 238 IFQAIKTHSEASG 250 >3T2N-A nrPDB Length = 372 Score = 107 bits (268), Expect = 4e-24, Method: Compositional matrix adjust. Identities = 77/254 (30%), Positives = 116/254 (45%), Gaps = 19/254 (7%) Query: 33 QIIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHV 92 +I+GG + + P+ S+R+ G H CGG LL WV++AAHCF R+ + A Sbjct: 117 RIVGGRDTSLGRWPWQVSLRYDGAHLCGGSLLSGDWVLTAAHCFPERNRVLSRWRVFAGA 176 Query: 93 LSTAEPTQQVFGIDALTTHPDYHPM------THANDICLLRLNGSAVLGPAVGLLRPPGR 146 ++ A P G+ A+ H Y P ++NDI L+ L+ L + + P Sbjct: 177 VAQASPHGLQLGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLTEYIQPVCLPA- 235 Query: 147 RARPPTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSS--WKGHLTLTMLCTR 204 + G C V GWG + + L EA+V ++ DVCN + + + M C Sbjct: 236 AGQALVDGKICTVTGWGNTQYYGQQAGVLQEARVPIISNDVCNGADFYGNQIKPKMFCAG 295 Query: 205 SGDSHRRGFCSADSGGPLVCRN--------RAHGLVSFSGLWCGDPKTPDVYTQVSAFVA 256 + C DSGGP VC + R G+VS+ G C + P VYT+VS F Sbjct: 296 YPEGGIDA-CQGDSGGPFVCEDSISRTPRWRLCGIVSW-GTGCALAQKPGVYTKVSDFRE 353 Query: 257 WIWDVVRRSSPQPG 270 WI+ ++ S G Sbjct: 354 WIFQAIKTHSEASG 367 >1SPJ-A nrPDB Length = 238 Score = 107 bits (268), Expect = 4e-24, Method: Compositional matrix adjust. Identities = 74/246 (30%), Positives = 112/246 (45%), Gaps = 21/246 (8%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVL 93 I+GG E HS+P+ A++ CGG L+ +WV++AAHC S + LG H L Sbjct: 1 IVGGWECEQHSQPWQAALYHFSTFQCGGILVHRQWVLTAAHCIS----DNYQLWLGRHNL 56 Query: 94 STAEPTQQV-----------FGIDALTTHPDYHPMTHANDICLLRLNGSA-VLGPAVGLL 141 E T Q F + L H +++D+ LLRL A + AV ++ Sbjct: 57 FDDENTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHDLMLLRLTEPADTITDAVKVV 116 Query: 142 RPPGRRARPPTAGTRCRVAGWGFVS-DFEELPPGLMEAKVRVLDPDVCNSSWKGHLTLTM 200 P P G+ C +GWG + + P L +++L D C + +T M Sbjct: 117 ELP---TEEPEVGSTCLASGWGSIEPENFSFPDDLQCVDLKILPNDECKKAHVQKVTDFM 173 Query: 201 LCTRSGDSHRRGFCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWD 260 LC + + C DSGGPL+C G+ S+ + CG P P V +V ++V WI D Sbjct: 174 LCVGHLEG-GKDTCVGDSGGPLMCDGVLQGVTSWGYVPCGTPNKPSVAVRVLSYVKWIED 232 Query: 261 VVRRSS 266 + +S Sbjct: 233 TIAENS 238 >1GVZ-A nrPDB Length = 237 Score = 107 bits (268), Expect = 5e-24, Method: Compositional matrix adjust. Identities = 75/247 (30%), Positives = 113/247 (45%), Gaps = 24/247 (9%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVL 93 IIGG E HS+P+ +V G CGG L+ +WV++AAHC S D + + LG H L Sbjct: 1 IIGGWECEKHSKPWQVAVYHQGHFQCGGVLVHPQWVLTAAHCMS-DDYQ---IWLGRHNL 56 Query: 94 STAEPTQQVFGIDALTTHPD-------------YHPMTHANDICLLRLNGSAVLGPAVGL 140 S E T Q + P Y ++H D+ LLRL A + AV + Sbjct: 57 SKDEDTAQFHQVSDSFLDPQFDLSLLKKKYLRPYDDISH--DLMLLRLAQPARITDAVKI 114 Query: 141 LRPPGRRARPPTAGTRCRVAGWGFVSDFEELPPGLME-AKVRVLDPDVCNSSWKGHLTLT 199 L P + P G+ C +GWG +S F G ++ ++R+ + C ++ +T Sbjct: 115 LDLP---TQEPKLGSTCYTSGWGLISTFTNRGSGTLQCVELRLQSNEKCARAYPEKMTEF 171 Query: 200 MLCTRSGDSHRRGFCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIW 259 +LC D C DSGG L+C G+ S+ C D V+T+V WI Sbjct: 172 VLCATHRDD-SGSICLGDSGGALICDGVFQGITSWGYSECADFNDNFVFTKVMPHKKWIK 230 Query: 260 DVVRRSS 266 + + ++S Sbjct: 231 ETIEKNS 237 >1YC0-A nrPDB Length = 283 Score = 107 bits (267), Expect = 6e-24, Method: Compositional matrix adjust. Identities = 82/245 (33%), Positives = 118/245 (48%), Gaps = 19/245 (7%) Query: 33 QIIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGL-VVLGAH 91 +IIGG P S P++A++ + G C G L+ WVVSAAHCFSH R + VVLG H Sbjct: 35 RIIGGSSSLPGSHPWLAAI-YIGDSFCAGSLVHTCWVVSAAHCFSHSPPRDSVSVVLGQH 93 Query: 92 VLSTAEPTQQVFGIDA---LTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRA 148 + Q FGI+ T + ++P H D+ L+RL P Sbjct: 94 FFNRTTDVTQTFGIEKYIPYTLYSVFNPSDH--DLVLIRLKKKGDRCATRSQFVQPICLP 151 Query: 149 RPPT---AGTRCRVAGWGFVSD-FEELPPGLMEAKVRVLDPDVCNS--SWKGHLTLTMLC 202 P + AG +C++AGWG + + L EA V ++ C+S + ++ MLC Sbjct: 152 EPGSTFPAGHKCQIAGWGHLDENVSGYSSSLREALVPLVADHKCSSPEVYGADISPNMLC 211 Query: 203 TRSGDSHRRGFCSADSGGPLVCRNRA----HGLVSFSGLWCGDPKTPDVYTQVSAFVAWI 258 D + C DSGGPL C +G++S+ G CG P VYT+V+ +V WI Sbjct: 212 AGYFDC-KSDACQGDSGGPLACEKNGVAYLYGIISW-GDGCGRLHKPGVYTRVANYVDWI 269 Query: 259 WDVVR 263 D +R Sbjct: 270 NDRIR 274 >2R0L-A nrPDB Length = 248 Score = 106 bits (265), Expect = 9e-24, Method: Compositional matrix adjust. Identities = 82/244 (33%), Positives = 117/244 (47%), Gaps = 19/244 (7%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGL-VVLGAHV 92 IIGG P S P++A++ + G C G L+ WVVSAAHCFSH R + VVLG H Sbjct: 1 IIGGSSSLPGSHPWLAAI-YIGDSFCAGSLVHTCWVVSAAHCFSHSPPRDSVSVVLGQHF 59 Query: 93 LSTAEPTQQVFGIDA---LTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRAR 149 + Q FGI+ T + ++P H D+ L+RL P Sbjct: 60 FNRTTDVTQTFGIEKYIPYTLYSVFNPSDH--DLVLIRLKKKGDRCATRSQFVQPICLPE 117 Query: 150 PPT---AGTRCRVAGWGFVSD-FEELPPGLMEAKVRVLDPDVCNS--SWKGHLTLTMLCT 203 P + AG +C++AGWG + + L EA V ++ C+S + ++ MLC Sbjct: 118 PGSTFPAGHKCQIAGWGHLDENVSGYSSSLREALVPLVADHKCSSPEVYGADISPNMLCA 177 Query: 204 RSGDSHRRGFCSADSGGPLVCRNRA----HGLVSFSGLWCGDPKTPDVYTQVSAFVAWIW 259 D + C DSGGPL C +G++S+ G CG P VYT+V+ +V WI Sbjct: 178 GYFDC-KSDACQGDSGGPLACEKNGVAYLYGIISW-GDGCGRLHKPGVYTRVANYVDWIN 235 Query: 260 DVVR 263 D +R Sbjct: 236 DRIR 239 >1AO5-A nrPDB Length = 237 Score = 106 bits (265), Expect = 9e-24, Method: Compositional matrix adjust. Identities = 68/245 (27%), Positives = 115/245 (46%), Gaps = 20/245 (8%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVL 93 ++GG +S+P+ +V + +H CGG LL WV++AAHC+ + V LG + L Sbjct: 1 VVGGFNCEKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQ----YEVWLGKNKL 56 Query: 94 STAEPTQQVFGIDALTTHPDYHP-----------MTHANDICLLRLNGSAVLGPAVGLLR 142 EP+ Q + HP ++ ++D+ LLRL+ A + V + Sbjct: 57 FQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSDDLMLLRLSKPADITDVVKPIA 116 Query: 143 PPGRRARPPTAGTRCRVAGWGFVSDFE-ELPPGLMEAKVRVLDPDVCNSSWKGHLTLTML 201 P + +P G++C +GWG ++ + P L + +L + C + +T ML Sbjct: 117 LPTKEPKP---GSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDVML 173 Query: 202 CTRSGDSHRRGFCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDV 261 C + C DSGGPL+C G S+ + CG P P +YT + F +WI D Sbjct: 174 CAGEMGGGKDT-CRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDT 232 Query: 262 VRRSS 266 + +++ Sbjct: 233 MMKNA 237 >3W94-A nrPDB Length = 235 Score = 106 bits (264), Expect = 1e-23, Method: Compositional matrix adjust. Identities = 76/238 (31%), Positives = 117/238 (49%), Gaps = 11/238 (4%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRD--LRTGLVVLGAH 91 ++GG + P+M S+ + G+H CG L+ W+++AAHC ++ L+ VLG H Sbjct: 1 VVGGVNAEKGAWPWMVSLHWRGRHGCGASLIGRDWLLTAAHCVYGKNTHLQYWSAVLGLH 60 Query: 92 VLSTAEPTQ-QVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARP 150 S+ + Q+ +D + + +Y+ T DI ++ L V + Sbjct: 61 AQSSMNSQEVQIRQVDRIIINKNYNRRTKEADIAMMHLQQPVNFTEWVLPVCLASEDQHF 120 Query: 151 PTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWKGH-LTLTMLCTRSGDSH 209 P AG RC +AGWG ++ LP L EA+V ++D D C + T +MLC + Sbjct: 121 P-AGRRCFIAGWGRDAEGGSLPDILQEAEVPLVDQDECQRLLPEYTFTSSMLCAGYPEGG 179 Query: 210 RRGFCSADSGGPLVCRNRAH----GLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVR 263 C DSGGPL+C A G+ SF G+ CG P+ P Y +VSAF +WI + R Sbjct: 180 VDS-CQGDSGGPLMCLEDARWTLIGVTSF-GVGCGRPERPGAYARVSAFTSWIAETRR 235 >1SGF-A nrPDB Length = 240 Score = 105 bits (263), Expect = 2e-23, Method: Compositional matrix adjust. Identities = 66/228 (28%), Positives = 110/228 (48%), Gaps = 20/228 (8%) Query: 43 HSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVLSTAEPTQQV 102 +S+P+ +V ++ CGG LL WV++AAHC++ + V LG + EP+ Q Sbjct: 13 NSQPWHVAVYRFNKYQCGGVLLDRNWVLTAAHCYNDK----YQVWLGKNNFLEDEPSDQH 68 Query: 103 FGIDALTTHPDYH-----------PMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARPP 151 + HPD++ ++ND+ LLRL+ A + +++P P Sbjct: 69 RLVSKAIPHPDFNMSLLNEHTPQPEDDYSNDLMLLRLSKPADI---TDVVKPITLPTEEP 125 Query: 152 TAGTRCRVAGWGFVSDFE-ELPPGLMEAKVRVLDPDVCNSSWKGHLTLTMLCTRSGDSHR 210 G+ C +GWG + + + P L +++L + C+ + + +T MLC D Sbjct: 126 KLGSTCLASGWGSTTPIKFKYPDDLQCVNLKLLPNEDCDKAHEMKVTDAMLCAGEMDGGS 185 Query: 211 RGFCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWI 258 C DSGGPL+C G+ S+ CG+P P VYT++ F +WI Sbjct: 186 YT-CEHDSGGPLICDGILQGITSWGPEPCGEPTEPSVYTKLIKFSSWI 232 >1LTO-A nrPDB Length = 245 Score = 104 bits (260), Expect = 4e-23, Method: Compositional matrix adjust. Identities = 80/247 (32%), Positives = 116/247 (46%), Gaps = 32/247 (12%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQ---HHCGGFLLRARWVVSAAHCF--SHRDLRTGLVVL 88 I+GG E P+ S+R + H CGG L+ +WV++AAHC +DL T V L Sbjct: 1 IVGGQEAPRSKWPWQVSLRVRDRYWMHFCGGSLIHPQWVLTAAHCLGPDVKDLATLRVQL 60 Query: 89 GAHVLSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAV-GLLRPPGRR 147 L + Q+ + + HP ++ + DI LL L + V ++ PP Sbjct: 61 REQHLYYQD---QLLPVSRIIVHPQFYIIQTGADIALLELEEPVNISSRVHTVMLPPASE 117 Query: 148 ARPPTAGTRCRVAGWGFVSDFEELPP--GLMEAKVRVLDPDVCNSSWKGHLTL------- 198 PP G C V GWG V + E LPP L + KV +++ +C++ K HL Sbjct: 118 TFPP--GMPCWVTGWGDVDNDEPLPPPFPLKQVKVPIMENHICDA--KYHLGAYTGDDVR 173 Query: 199 ----TMLCTRSGDSHRRGFCSADSGGPLVCRNRAHGLVSFSGLW---CGDPKTPDVYTQV 251 MLC +G+S R C DSGGPLVC+ L + W C P P +YT+V Sbjct: 174 IIRDDMLC--AGNSQRDS-CKGDSGGPLVCKVNGTWLQAGVVSWDEGCAQPNRPGIYTRV 230 Query: 252 SAFVAWI 258 + ++ WI Sbjct: 231 TYYLDWI 237 >2AIQ-A nrPDB Length = 231 Score = 104 bits (259), Expect = 5e-23, Method: Compositional matrix adjust. Identities = 76/247 (30%), Positives = 114/247 (46%), Gaps = 26/247 (10%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVL 93 +IGG E + ++A V G CGG L+ WV++A HC D + LG H L Sbjct: 1 VIGGDECNINEHRFLALVYANGSL-CGGTLINQEWVLTARHC----DRGNMRIYLGMHNL 55 Query: 94 STAEPTQQVFGIDALTTHPD--YHPMTHAND------ICLLRLNGSAVLGPAVGLLRPPG 145 +V DAL P Y + ND I L+RLN + L P Sbjct: 56 -------KVLNKDALRRFPKEKYFCLNTRNDTIWDKDIMLIRLNRPVRNSAHIAPLSLP- 107 Query: 146 RRARPPTAGTRCRVAGWGFVSDFEELPPGLME-AKVRVLDPDVCNSSWKGHLTLTMLCTR 204 + PP+ G+ CR+ GWG ++ P + A + +LD VC +++KG L T LC Sbjct: 108 --SNPPSVGSVCRIMGWGTITSPNATLPDVPHCANINILDYAVCQAAYKG-LAATTLCAG 164 Query: 205 SGDSHRRGFCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVRR 264 + + C DSGGPL+C + G++S G C P+ P +YT+V + WI ++ Sbjct: 165 ILEGGK-DTCKGDSGGPLICNGQFQGILSVGGNPCAQPRKPGIYTKVFDYTDWIQSIISG 223 Query: 265 SSPQPGP 271 ++ P Sbjct: 224 NTDATCP 230 >1PYT-D nrPDB Length = 251 Score = 103 bits (258), Expect = 6e-23, Method: Compositional matrix adjust. Identities = 75/239 (31%), Positives = 117/239 (48%), Gaps = 17/239 (7%) Query: 32 AQIIGGHEVTPHSRPYMASVRF----GGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVV 87 A+++GG + PHS P+ S+++ +H CGG L+ V++AAHC S+ T V Sbjct: 12 ARVVGGEDAIPHSWPWQISLQYLRDNTWRHTCGGTLITPNHVLTAAHCISNT--LTYRVA 69 Query: 88 LGAHVLSTAEPTQQVF-GIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGR 146 LG + L + ++ G+D + H ++ NDI L++L + LG + + P Sbjct: 70 LGKNNLEVEDEAGSLYVGVDTIFVHEKWNSFLVRNDIALIKLAETVELGDTIQVACLPSE 129 Query: 147 RARPPTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSS--WKGHLTLTMLCTR 204 + P C V GWG + + L + V+D C+ W + TM+C Sbjct: 130 GSLLP-QDYPCFVTGWGRLYTNGPIAAELQQGLQPVVDYATCSQRDWWGTTVKETMVC-- 186 Query: 205 SGDSHRRGFCSADSGGPLVCRNRAH----GLVSF-SGLWCGDPKTPDVYTQVSAFVAWI 258 +G C+ DSGGPL C+ G+VSF SGL C K P V+T+VSA++ WI Sbjct: 187 AGGDGVISACNGDSGGPLNCQADGQWDVRGIVSFGSGLSCNTFKKPTVFTRVSAYIDWI 245 >1BDA-A nrPDB Length = 265 Score = 103 bits (258), Expect = 7e-23, Method: Compositional matrix adjust. Identities = 90/281 (32%), Positives = 128/281 (45%), Gaps = 40/281 (14%) Query: 4 GLRGWGRPLLTVATALMLPVKPPAGSWGAQIIGGHEVTPHSRPYMASVRFGGQHHCGGFL 63 GLR + +P + L + + W A I H +P G + CGG L Sbjct: 3 GLRQYSQPQFRIKGGLFADI--ASHPWQAAIFAKHRRSP-----------GERFLCGGIL 49 Query: 64 LRARWVVSAAHCFSHRDLRTGL-VVLGAHVLSTAEPTQQVFGIDALTTHPDYHPMTHAND 122 + + W++SAAHCF R L V+LG +Q F ++ H ++ T+ ND Sbjct: 50 ISSCWILSAAHCFQERFPPHHLTVILGRTYRVVPGEEEQKFEVEKYIVHKEFDDDTYDND 109 Query: 123 ICLLRLNG-SAVLGPAVGLLR----PPGRRARPPTAGTRCRVAGWGFVSDFEELPP---- 173 I LL+L S+ ++R PP P T C ++G+G E L P Sbjct: 110 IALLQLKSDSSRCAQESSVVRTVCLPPADLQLPD--WTECELSGYG---KHEALSPFYSE 164 Query: 174 GLMEAKVRVLDPDVCNSSWKGHLTLT--MLC---TRSG--DSHRRGFCSADSGGPLVCRN 226 L EA VR+ C S + T+T MLC TRSG ++ C DSGGPLVC N Sbjct: 165 RLKEAHVRLYPSSRCTSQHLLNRTVTDNMLCAGDTRSGGPQANLHDACQGDSGGPLVCLN 224 Query: 227 RAH----GLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVR 263 G++S+ GL CG P VYT+V+ ++ WI D +R Sbjct: 225 DGRMTLVGIISW-GLGCGQKDVPGVYTKVTNYLDWIRDNMR 264 >2CGA-A nrPDB Length = 245 Score = 103 bits (257), Expect = 8e-23, Method: Compositional matrix adjust. Identities = 79/246 (32%), Positives = 112/246 (45%), Gaps = 18/246 (7%) Query: 21 LPVKPPAGSWGAQIIGGHEVTPHSRPYMASVR-FGGQHHCGGFLLRARWVVSAAHC-FSH 78 +P P S ++I+ G E P S P+ S++ G H CGG L+ WVV+AAHC + Sbjct: 3 VPAIQPVLSGLSRIVNGEEAVPGSWPWQVSLQDKTGFHFCGGSLINENWVVTAAHCGVTT 62 Query: 79 RDLRTGLVVLGAHVLSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAV 138 D +VV G ++ Q I + + Y+ +T NDI LL+L+ +A V Sbjct: 63 SD----VVVAGEFDQGSSSEKIQKLKIAKVFKNSKYNSLTINNDITLLKLSTAASFSQTV 118 Query: 139 GLLRPPGRRARPPTAGTRCRVAGWGFV-SDFEELPPGLMEAKVRVLDPDVCNSSWKGHLT 197 + P + AGT C GWG P L +A + +L C W + Sbjct: 119 SAVCLP-SASDDFAAGTTCVTTGWGLTRYTNANTPDRLQQASLPLLSNTNCKKYWGTKIK 177 Query: 198 LTMLCT-RSGDSHRRGFCSADSGGPLVCRNRAH----GLVSFSGLWCGDPKTPDVYTQVS 252 M+C SG S C DSGGPLVC+ G+VS+ C TP VY +V+ Sbjct: 178 DAMICAGASGVSS----CMGDSGGPLVCKKNGAWTLVGIVSWGSSTC-STSTPGVYARVT 232 Query: 253 AFVAWI 258 A V W+ Sbjct: 233 ALVNWV 238 >1AZZ-A nrPDB Length = 226 Score = 103 bits (256), Expect = 1e-22, Method: Compositional matrix adjust. Identities = 69/226 (30%), Positives = 106/226 (46%), Gaps = 9/226 (3%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVL 93 I+GG E P+S P+ A++ + CGG L+ W+++AAHC VVLGAH + Sbjct: 1 IVGGVEAVPNSWPHQAALFIDDMYFCGGSLISPEWILTAAHCMDGAGFVD--VVLGAHNI 58 Query: 94 STAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARPPTA 153 E TQ T H +Y+ +NDI ++RL L A+ + P Sbjct: 59 REDEATQVTIQSTDFTVHENYNSFVISNDIAVIRLPVPVTLTAAIATVGLPSTDVG---V 115 Query: 154 GTRCRVAGWGFVSDFE-ELPPGLMEAKVRVLDPDVCNSSWKGHLTLTMLCTRSGDSHRRG 212 GT GWG SD + L + V ++ C++ + G +T +C S + +G Sbjct: 116 GTVVTPTGWGLPSDSALGISDVLRQVDVPIMSNADCDAVY-GIVTDGNICIDS--TGGKG 172 Query: 213 FCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWI 258 C+ DSGGPL +G+ SF + PD +T+V+ F+ WI Sbjct: 173 TCNGDSGGPLNYNGLTYGITSFGAAAGCEAGYPDAFTRVTYFLDWI 218 >4MPW-A nrPDB Length = 245 Score = 102 bits (254), Expect = 2e-22, Method: Compositional matrix adjust. Identities = 82/248 (33%), Positives = 117/248 (47%), Gaps = 34/248 (13%) Query: 34 IIGGHEVTPHSRPYMASVRFGG---QHHCGGFLLRARWVVSAAHCF--SHRDLRTGLVVL 88 I+GG E P+ S+R G H CGG L+ +WV++AAHC +DL V L Sbjct: 1 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 60 Query: 89 GAHVLSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLR-PPGRR 147 L + Q+ + + HP ++ DI LL L + V + PP Sbjct: 61 REQHLYYQD---QLLPVSRIIVHPQFYTAQIGADIALLELEEPVKVSSHVHTVTLPPASE 117 Query: 148 ARPPTAGTRCRVAGWGFVSDFEELPP--GLMEAKVRVLDPDVCNSSWKGHLTL------- 198 PP G C V GWG V + E LPP L + KV +++ +C++ K HL Sbjct: 118 TFPP--GMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDA--KYHLGAYTGDDVR 173 Query: 199 ----TMLCTRSGDSHRRGFCSADSGGPLVCRNR----AHGLVSFSGLWCGDPKTPDVYTQ 250 MLC +G++ RR C DSGGPLVC+ G+VS+ G C P P +YT+ Sbjct: 174 IVRDDMLC--AGNT-RRDSCQGDSGGPLVCKVNGTWLQAGVVSW-GEGCAQPNRPGIYTR 229 Query: 251 VSAFVAWI 258 V+ ++ WI Sbjct: 230 VTYYLDWI 237 >3E0N-B nrPDB Length = 271 Score = 102 bits (253), Expect = 3e-22, Method: Compositional matrix adjust. Identities = 79/260 (30%), Positives = 113/260 (43%), Gaps = 18/260 (6%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCF-SHRDLRTGLVVLGAHV 92 I GG P+ S+ + G H CGG L+ +WV+SAAHCF S V LGAH Sbjct: 1 ITGGSSAVAGQWPWQVSITYEGVHVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKLGAHQ 60 Query: 93 LSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARPPT 152 L + +V + + HP Y DI LL+L+ + + P +A P Sbjct: 61 LDSYSEDAKVSTLKDIIPHPSYLQEGSQGDIALLQLSRPITFSRYIRPISLPAAQASFPN 120 Query: 153 AGTRCRVAGWGFVSDFEEL--PPGLMEAKVRVLDPDVCNSSWK--------GHLTLTMLC 202 G C V GWG V+ L P L + +V ++ + CNS + + M+C Sbjct: 121 -GLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNSLYNIDAKPEEPHFVQEDMVC 179 Query: 203 TRSGDSHRRGFCSADSGGPLVCRNRA----HGLVSFSGLWCGDPKTPDVYTQVSAFVAWI 258 + + C DSGGPL C G+VS+ G CG P VYT S++ +WI Sbjct: 180 AGYVEGGKDA-CQGDSGGPLSCPVEGLWYLTGIVSW-GDACGARNRPGVYTLASSYASWI 237 Query: 259 WDVVRRSSPQPGPLPGTTRP 278 V P+ P ++P Sbjct: 238 QSKVTELQPRVVPQTQESQP 257 >4XDE-A nrPDB Length = 257 Score = 99.8 bits (247), Expect = 1e-21, Method: Compositional matrix adjust. Identities = 83/241 (34%), Positives = 122/241 (50%), Gaps = 20/241 (8%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGL-VVLGAHV 92 ++GG + PY+A++ + G C G L+ WV++AAHC R L VVLG Sbjct: 3 VVGGLVALRGAHPYIAAL-YWGHSFCAGSLIAPCWVLTAAHCLQDRPAPEDLTVVLGQER 61 Query: 93 LSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRL----NGS-AVLGPAVGLLRPPGRR 147 + + Q + + H + P+++ +D+ LLRL +GS A+L P V + P Sbjct: 62 RNHSCEPCQTLAVRSYRLHEAFSPVSYQHDLALLRLQEDADGSCALLSPYVQPVSLPSGA 121 Query: 148 ARPPTAGTRCRVAGWGFVSD-FEELPPGLMEAKVRVLDPDVCNS-SWKGHLTL-TMLCTR 204 AR P+ T C+VAGWG + EE L EA+V L + C++ G L MLC Sbjct: 122 AR-PSETTLCQVAGWGHQFEGAEEYASFLQEAQVPFLSLERCSAPDVHGSSILPGMLCAG 180 Query: 205 SGDSHRRGFCSADSGGPLVCRNRA-------HGLVSFSGLWCGDPKTPDVYTQVSAFVAW 257 + C DSGGPLVC ++A G++S+ G CGD P VYT V+ ++AW Sbjct: 181 FLEGGTDA-CQGDSGGPLVCEDQAAERRLTLQGIISW-GSGCGDRNKPGVYTDVAYYLAW 238 Query: 258 I 258 I Sbjct: 239 I 239 >5UGG-A nrPDB Length = 251 Score = 99.4 bits (246), Expect = 2e-21, Method: Compositional matrix adjust. Identities = 84/246 (34%), Positives = 111/246 (45%), Gaps = 28/246 (11%) Query: 33 QIIGGHEVTPHSRPYMASVRFG-GQHHCGGFLLRARWVVSAAHCFSHRDLRTGL-VVLGA 90 +++GG PHS P+ S+R G H CGG L+ WV++AAHC + V+LGA Sbjct: 21 RVVGGCVAHPHSWPWQVSLRTRFGMHFCGGTLISPEWVLTAAHCLEKSPRPSSYKVILGA 80 Query: 91 HVLSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAV--GLLRPPGRRA 148 H EP Q + L P DI LL+L+ AV+ V L P Sbjct: 81 HQEVNLEPHVQEIEVSRLFLEPT------RKDIALLKLSSPAVITDKVIPACLPSPNYVV 134 Query: 149 RPPTAGTRCRVAGWGFVSDFEELPPGLM-EAKVRVLDPDVCN--SSWKGHLTLTMLCTRS 205 T C + GWG GL+ EA++ V++ VCN G + T LC Sbjct: 135 ---ADRTECFITGWGETQG--TFGAGLLKEAQLPVIENKVCNRYEFLNGRVQSTELCA-- 187 Query: 206 GDSHRRG---FCSADSGGPLVCRNRAHGL---VSFSGLWCGDPKTPDVYTQVSAFVAWIW 259 H G C DSGGPLVC + + V+ GL C P P VY +VS FV WI Sbjct: 188 --GHLAGGTDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCARPNKPGVYVRVSRFVTWIE 245 Query: 260 DVVRRS 265 V+R + Sbjct: 246 GVMRNN 251 >4H4F-A nrPDB Length = 249 Score = 99.0 bits (245), Expect = 2e-21, Method: Compositional matrix adjust. Identities = 73/238 (30%), Positives = 116/238 (48%), Gaps = 18/238 (7%) Query: 34 IIGGHEVTPHSRPYMASVRF----GGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLG 89 ++GG + PHS P+ S+++ +H CGG L+ + +V++AAHC S + RT V +G Sbjct: 1 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCIS--NTRTYRVAVG 58 Query: 90 AHVLSTAEPTQQVF-GIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRA 148 + L + +F G+D + H ++ + NDI L++L L + + P + + Sbjct: 59 KNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDS 118 Query: 149 RPPTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCN--SSWKGHLTLTMLCTRSG 206 P C V GWG + + L + V+D C+ W + TM+C +G Sbjct: 119 LLP-KDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVC--AG 175 Query: 207 DSHRRGFCSADSGGPLVCRN-----RAHGLVSF-SGLWCGDPKTPDVYTQVSAFVAWI 258 C+ DSGGPL C+ G+VSF S C K P VYT+VSA++ WI Sbjct: 176 GDGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWI 233 >4Z6A-H nrPDB Length = 249 Score = 98.6 bits (244), Expect = 3e-21, Method: Compositional matrix adjust. Identities = 84/246 (34%), Positives = 112/246 (45%), Gaps = 10/246 (4%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSH-RDLRTGLVVLGAHV 92 I+GG P+ + G CGG L+ WVVSAAHCF ++ R + VLG H Sbjct: 1 IVGGKVCPKGECPWQVLLLVNGAQLCGGTLINTIWVVSAAHCFDKIKNWRNLIAVLGEHD 60 Query: 93 LSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARPPT 152 LS + +Q + + Y P T +DI LLRL+ VL V L P R T Sbjct: 61 LSEHDGDEQSRRVAQVIIPSTYVPGTTNHDIALLRLHQPVVLTDHVVPLCLPERTFSERT 120 Query: 153 -AGTRCR-VAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWKGHLTLTMLCTRSGDSHR 210 A R V+GWG + D LM V L C +S+ G +T M C D + Sbjct: 121 LAFVRFSLVSGWGQLLDRGATALELMVLNVPRLMTQDCEASYPGKITEYMFCAGYSDGSK 180 Query: 211 RGFCSADSGGPLVCRNRA----HGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVRRSS 266 C DSGGP R G+VS+ G C VYT+VS ++ W+ ++ RS Sbjct: 181 DS-CKGDSGGPHATHYRGTWYLTGIVSW-GQGCATVGHFGVYTRVSQYIEWLQKLM-RSE 237 Query: 267 PQPGPL 272 P+PG L Sbjct: 238 PRPGVL 243 >4DUR-A nrPDB Length = 791 Score = 98.2 bits (243), Expect = 3e-21, Method: Compositional matrix adjust. Identities = 84/246 (34%), Positives = 111/246 (45%), Gaps = 28/246 (11%) Query: 33 QIIGGHEVTPHSRPYMASVRFG-GQHHCGGFLLRARWVVSAAHCFSHRDLRTGL-VVLGA 90 +++GG PHS P+ S+R G H CGG L+ WV++AAHC + V+LGA Sbjct: 561 RVVGGCVAHPHSWPWQVSLRTRFGMHFCGGTLISPEWVLTAAHCLEKSPRPSSYKVILGA 620 Query: 91 HVLSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAV--GLLRPPGRRA 148 H EP Q + L P DI LL+L+ AV+ V L P Sbjct: 621 HQEVNLEPHVQEIEVSRLFLEPT------RKDIALLKLSSPAVITDKVIPACLPSPNYVV 674 Query: 149 RPPTAGTRCRVAGWGFVSDFEELPPGLM-EAKVRVLDPDVCN--SSWKGHLTLTMLCTRS 205 T C + GWG GL+ EA++ V++ VCN G + T LC Sbjct: 675 ---ADRTECFITGWGETQG--TFGAGLLKEAQLPVIENKVCNRYEFLNGRVQSTELCA-- 727 Query: 206 GDSHRRG---FCSADSGGPLVCRNRAHGL---VSFSGLWCGDPKTPDVYTQVSAFVAWIW 259 H G C DSGGPLVC + + V+ GL C P P VY +VS FV WI Sbjct: 728 --GHLAGGTDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCARPNKPGVYVRVSRFVTWIE 785 Query: 260 DVVRRS 265 V+R + Sbjct: 786 GVMRNN 791 >4IGD-A nrPDB Length = 406 Score = 97.8 bits (242), Expect = 5e-21, Method: Compositional matrix adjust. Identities = 77/256 (30%), Positives = 110/256 (42%), Gaps = 32/256 (12%) Query: 32 AQIIGGHEVTPHSRPYMASV-RFGGQHHCGGFLLRARWVVSAAHCFSHRDL--------- 81 AQI G + P++A + GQ CGG LL + W+V+AAHC H+ L Sbjct: 154 AQIFNGRPAQKGTTPWIAMLSHLNGQPFCGGSLLGSSWIVTAAHCL-HQSLDPEDPTLRD 212 Query: 82 ------RTGLVVLGAHVLSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLG 135 ++LG H ++ +Q G+ T HP Y P T ND+ L+ L S VL Sbjct: 213 SDLLSPSDFKIILGKHWRLRSDENEQHLGVKHTTLHPQYDPNTFENDVALVELLESPVLN 272 Query: 136 PAVG-LLRPPGRRARPPTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSW-- 192 V + P G P G V+GWG + P LME ++ ++D C ++ Sbjct: 273 AFVMPICLPEG----PQQEGAMVIVSGWG-KQFLQRFPETLMEIEIPIVDHSTCQKAYAP 327 Query: 193 -KGHLTLTMLCTRSGDSHRRGFCSADSGGPLVCRNRAHGLVSFSGL--W---CGDPKTPD 246 K +T M+C + + C+ DSGGP+V NR G G W CG Sbjct: 328 LKKKVTRDMICAGEKEGGKDA-CAGDSGGPMVTLNRERGQWYLVGTVSWGDDCGKKDRYG 386 Query: 247 VYTQVSAFVAWIWDVV 262 VY+ + WI V Sbjct: 387 VYSYIHHNKDWIQRVT 402 >1FXY-A nrPDB Length = 228 Score = 97.8 bits (242), Expect = 5e-21, Method: Compositional matrix adjust. Identities = 67/235 (28%), Positives = 104/235 (44%), Gaps = 9/235 (3%) Query: 34 IIGGHEVTPHSRPYMAS-VRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHV 92 I+GG+ P+ A + + CGG +L ++++AAHC + V +G Sbjct: 1 IVGGYNCKDGEVPWQALLINEENEGFCGGTILSEFYILTAAHCLYQ--AKRFKVRVGDRN 58 Query: 93 LSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARPPT 152 E + V ++ + H + T+ DI +LRL V P PP Sbjct: 59 TEQEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVA---PASLPTAPPA 115 Query: 153 AGTRCRVAGWGFV-SDFEELPPGLMEAKVRVLDPDVCNSSWKGHLTLTMLCTRSGDSHRR 211 GT+C ++GWG S + P L VL C +S+ G +T M C + + Sbjct: 116 TGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKITSNMFCVGFLEGGKD 175 Query: 212 GFCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVRRSS 266 C DSGGP+VC + G+VS+ G C P VYT+V +V WI + + +S Sbjct: 176 S-CQGDSGGPVVCNGQLQGVVSW-GDGCAQKNKPGVYTKVYNYVKWIKNTIAANS 228 >4GSO-A nrPDB Length = 232 Score = 97.1 bits (240), Expect = 7e-21, Method: Compositional matrix adjust. Identities = 66/228 (28%), Positives = 105/228 (46%), Gaps = 13/228 (5%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVL 93 ++GG E + P++A + G + CG L+ WVV+AAHC D + LG H Sbjct: 1 VLGGDECDINEHPFLAFLYSHG-YFCGLTLINQEWVVTAAHC----DSTNFQMQLGVHSK 55 Query: 94 STAEPTQQVFGIDALTTHPDYHPMTHA--NDICLLRLNGSAVLGPAVGLLRPPGRRARPP 151 +Q P+ + M+ DI L++L+ + L P + PP Sbjct: 56 KVLNEDEQTRNPKEKFICPNKN-MSEVLDKDIMLIKLDKPISNSKHIAPLSLP---SNPP 111 Query: 152 TAGTRCRVAGWGFVSDFEELPPGL-MEAKVRVLDPDVCNSSWKGHLTLTMLCTRSGDSHR 210 + G+ CR+ GWG ++ E P + A + ++D +VC ++ G T LC + + Sbjct: 112 SVGSVCRIMGWGSITIPNETYPDVPYCANINLVDYEVCQGAYNGLPAKTTLCAGVLEGGK 171 Query: 211 RGFCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWI 258 C DSGGPL+C + G+VS+ CG P +YT V + WI Sbjct: 172 DT-CVGDSGGPLICNGQFQGIVSYGAHSCGQGPKPGIYTNVFDYTDWI 218 >3DFJ-A nrPDB Length = 263 Score = 97.1 bits (240), Expect = 8e-21, Method: Compositional matrix adjust. Identities = 75/246 (30%), Positives = 106/246 (43%), Gaps = 18/246 (7%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCF-SHRDLRTGLVVLGAHV 92 I GG P+ S+ + G H CGG L+ +WV+SAAHCF S V LGAH Sbjct: 1 ITGGSSAVAGQWPWQVSITYEGVHVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKLGAHQ 60 Query: 93 LSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARPPT 152 L + +V + + HP Y DI LL+L+ + + P A P Sbjct: 61 LDSYSEDAKVSTLKDIIPHPSYLQEGSQGDIALLQLSRPITFSRYIRPISLPAANASFPN 120 Query: 153 AGTRCRVAGWGFVSDFEEL--PPGLMEAKVRVLDPDVCNSSWK--------GHLTLTMLC 202 G C V GWG V+ L P L + +V ++ + CN+ + + M+C Sbjct: 121 -GLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNALYNIDAKPEEPHFVQEDMVC 179 Query: 203 TRSGDSHRRGFCSADSGGPLVCRNRA----HGLVSFSGLWCGDPKTPDVYTQVSAFVAWI 258 + + C DSGGPL C G+VS+ G CG P VYT S++ +WI Sbjct: 180 AGYVEGGKDA-CQGDSGGPLSCPVEGLWYLTGIVSW-GDACGARNRPGVYTLASSYASWI 237 Query: 259 WDVVRR 264 V Sbjct: 238 QSKVTE 243 >1A5I-A nrPDB Length = 265 Score = 96.3 bits (238), Expect = 1e-20, Method: Compositional matrix adjust. Identities = 84/276 (30%), Positives = 119/276 (43%), Gaps = 36/276 (13%) Query: 4 GLRGWGRPLLTVATALMLPVKPPAGSWGAQIIGGHEVTPHSRPYMASVRFGGQHHCGGFL 63 GLR + P L L + + W A I + + G + CGG L Sbjct: 3 GLRKYKEPQLHSTGGLFTDI--TSHPWQAAIFAQNRRSS-----------GERFLCGGIL 49 Query: 64 LRARWVVSAAHCFSHRDLRTGL-VVLGAHVLSTAEPTQQVFGIDALTTHPDYHPMTHAND 122 + + WV++AAHCF L L VVLG +Q F + H ++ T+ ND Sbjct: 50 ISSCWVLTAAHCFQESYLPDQLKVVLGRTYRVKPGEEEQTFKVKKYIVHKEFDDDTYNND 109 Query: 123 ICLLRLNGSAVLGPAVGLLRPPGRRARPPTAG------TRCRVAGWG-FVSDFEELPPGL 175 I LL+L + P R P A T C ++G+G S L Sbjct: 110 IALLQLKSDS---PQCAQESDSVRAICLPEANLQLPDWTECELSGYGKHKSSSPFYSEQL 166 Query: 176 MEAKVRVLDPDVCNSSWKGHLTLT--MLC---TRSGDSH--RRGFCSADSGGPLVCRNRA 228 E VR+ C + + T+T MLC TRSG+ + C DSGGPLVC N Sbjct: 167 KEGHVRLYPSSRCAPKFLFNKTVTNNMLCAGDTRSGEIYPNVHDACQGDSGGPLVCMNDN 226 Query: 229 H----GLVSFSGLWCGDPKTPDVYTQVSAFVAWIWD 260 H G++S+ G+ CG+ P VYT+V+ ++ WI D Sbjct: 227 HMTLLGIISW-GVGCGEKDVPGVYTKVTNYLGWIRD 261 >1EKB-B nrPDB Length = 235 Score = 96.3 bits (238), Expect = 1e-20, Method: Compositional matrix adjust. Identities = 70/234 (29%), Positives = 105/234 (44%), Gaps = 13/234 (5%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTG--LVVLGAH 91 I+GG + + P++ ++ F Q CG L+ W+VSAAHC R++ VLG H Sbjct: 1 IVGGSDSREGAWPWVVALYFDDQQVCGASLVSRDWLVSAAHCVYGRNMEPSKWKAVLGLH 60 Query: 92 VLST-AEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVG-LLRPPGRRAR 149 + S P + ID + +P Y+ NDI ++ L + + P + Sbjct: 61 MASNLTSPQIETRLIDQIVINPHYNKRRKNNDIAMMHLEMKVNYTDYIQPICLPEENQVF 120 Query: 150 PPTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSW-KGHLTLTMLCTRSGDS 208 PP G C +AGWG + L EA V +L + C + ++T M+C ++ Sbjct: 121 PP--GRICSIAGWGALIYQGSTADVLQEADVPLLSNEKCQQQMPEYNITENMVCA-GYEA 177 Query: 209 HRRGFCSADSGGPLVCRNRAH----GLVSFSGLWCGDPKTPDVYTQVSAFVAWI 258 C DSGGPL+C+ G+ SF G C P P VY +V F WI Sbjct: 178 GGVDSCQGDSGGPLMCQENNRWLLAGVTSF-GYQCALPNRPGVYARVPRFTEWI 230 >4DGJ-A nrPDB Length = 235 Score = 95.5 bits (236), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 71/234 (30%), Positives = 105/234 (44%), Gaps = 13/234 (5%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTG--LVVLGAH 91 I+GG + + P++ + + + CG L+ + W+VSAAHC R+L +LG H Sbjct: 1 IVGGSDAKEGAWPWVVGLYYDDRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLH 60 Query: 92 VLSTAEPTQQV-FGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVG-LLRPPGRRAR 149 + S Q V ID + +P Y+ NDI ++ L + + P + Sbjct: 61 MKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPISLPEENQVF 120 Query: 150 PPTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSW-KGHLTLTMLCTRSGDS 208 PP G C +AGWG V L EA V +L + C + ++T M+C + Sbjct: 121 PP--GRNCSIAGWGTVVYQGTTADILQEADVPLLSNERCQQQMPEYNITENMICAGYEEG 178 Query: 209 HRRGFCSADSGGPLVCRNRAH----GLVSFSGLWCGDPKTPDVYTQVSAFVAWI 258 C DSGGPL+C+ G+ SF G C P P VY +VS F WI Sbjct: 179 GIDS-CQGDSGGPLMCQENNRWFLAGVTSF-GYECALPNRPGVYARVSRFTEWI 230 >4DJZ-B nrPDB Length = 251 Score = 94.4 bits (233), Expect = 4e-20, Method: Compositional matrix adjust. Identities = 74/250 (29%), Positives = 107/250 (42%), Gaps = 32/250 (12%) Query: 34 IIGGHEVTPHSRPYMASV-RFGGQHHCGGFLLRARWVVSAAHCFSHRDL----------- 81 I G + P++A + GQ CGG LL + W+V+AAHC H+ L Sbjct: 1 IFNGRPAQKGTTPWIAMLSHLNGQPFCGGSLLGSSWIVTAAHCL-HQSLDPKDPTLRDSD 59 Query: 82 ----RTGLVVLGAHVLSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPA 137 ++LG H ++ +Q G+ T HP Y P T ND+ L+ L S VL Sbjct: 60 LLSPSDFKIILGKHWRLRSDENEQHLGVKHTTLHPQYDPNTFENDVALVELLESPVLNAF 119 Query: 138 VG-LLRPPGRRARPPTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSW---K 193 V + P G P G V+GWG + P LME ++ ++D C ++ K Sbjct: 120 VMPICLPEG----PQQEGAMVIVSGWG-KQFLQRFPETLMEIEIPIVDHSTCQKAYAPLK 174 Query: 194 GHLTLTMLCTRSGDSHRRGFCSADSGGPLVCRNRAHGLVSFSGL--W---CGDPKTPDVY 248 +T M+C + + C+ DSGGP+V NR G G W CG VY Sbjct: 175 KKVTRDMICAGEKEGGKDA-CAGDSGGPMVTLNRERGQWYLVGTVSWGDDCGKKDRYGVY 233 Query: 249 TQVSAFVAWI 258 + + WI Sbjct: 234 SYIHHNKDWI 243 >2OQ5-A nrPDB Length = 232 Score = 94.4 bits (233), Expect = 6e-20, Method: Compositional matrix adjust. Identities = 74/234 (31%), Positives = 110/234 (47%), Gaps = 17/234 (7%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCF-SHRDLRTGLVVLGAHV 92 I+GG EV P+ AS+++ G H CG L+ A W+VSAAHCF ++++ G Sbjct: 1 IVGGTEVEEGEWPWQASLQWDGSHRCGATLINATWLVSAAHCFTTYKNPARWTASFGV-- 58 Query: 93 LSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVG-LLRPPGRRARPP 151 T +P++ G+ + H Y +H DI L L+ AV + P P Sbjct: 59 --TIKPSKMKRGLRRIIVHEKYKHPSHDYDISLAELSSPVPYTNAVHRVCLPDASYEFQP 116 Query: 152 TAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNS--SWKGHLTLTMLCTRSGDSH 209 G V G+G + + L +A+V ++D CN ++ +T MLC S + Sbjct: 117 --GDVMFVTGFGALKNDGYSQNHLRQAQVTLIDATTCNEPQAYNDAITPRMLCAGSLEG- 173 Query: 210 RRGFCSADSGGPLVCRNRAH-----GLVSFSGLWCGDPKTPDVYTQVSAFVAWI 258 + C DSGGPLV + G+VS+ G C P P VYT+V+A WI Sbjct: 174 KTDACQGDSGGPLVSSDARDIWYLAGIVSW-GDECAKPNKPGVYTRVTALRDWI 226 >5LHN-A nrPDB Length = 247 Score = 93.2 bits (230), Expect = 1e-19, Method: Compositional matrix adjust. Identities = 73/245 (29%), Positives = 113/245 (46%), Gaps = 23/245 (9%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQ------HHCGGFLLRARWVVSAAHCFSHRDLRTGLVV 87 I+GG ++P+ A++ + CGG L+ WV SAAHCF + VV Sbjct: 1 IVGGEFTEVENQPWFAAIYQKNKGGSPPSFKCGGSLISPCWVASAAHCFIQLPKKENYVV 60 Query: 88 -LGAHVLSTAEPTQQVFGIDALTTHPDYHP--MTHANDICLLRLNGS----AVLGPAVGL 140 LG S+ P + F ++ L H Y + + NDI LL++ S A ++ Sbjct: 61 YLGQSKESSYNPGEMKFEVEQLILHEYYREDSLAYHNDIALLKIRTSTGQCAQPSRSIQT 120 Query: 141 LRPPGRRARPPTAGTRCRVAGWGFVSDFEEL-PPGLMEAKVRVLDPDVCNS--SWKGHLT 197 + P R P G+ C + G+G S+ + L P L + V+++ + C + + Sbjct: 121 IALPPRFTDAPF-GSDCEITGFGKESESDYLYPKNLKMSVVKLVSHEQCMQPHYYGSEIN 179 Query: 198 LTMLCTRSGDSHRRGFCSADSGGPLVC----RNRAHGLVSFSGLWCGDPKTPDVYTQVSA 253 MLC + + C DSGGPL+C R G+VS+ G C + P VYT+VS Sbjct: 180 YKMLCAADPE-WKTDSCKGDSGGPLICNIEGRPTLSGIVSW-GRGCAEKNKPGVYTRVSH 237 Query: 254 FVAWI 258 F+ WI Sbjct: 238 FLDWI 242 >1SC8-U nrPDB Length = 262 Score = 91.3 bits (225), Expect = 5e-19, Method: Compositional matrix adjust. Identities = 77/250 (30%), Positives = 112/250 (44%), Gaps = 32/250 (12%) Query: 33 QIIGGHEVTPHSRPYMASV---RFGGQ--HHCGGFLLRARWVVSAAHCF-SHRDLRTGLV 86 +IIGG T ++P+ A++ GG + CGG L+ WV+SA HCF + +V Sbjct: 15 KIIGGEFTTIENQPWFAAIYRRHRGGSVTYVCGGSLISPCWVISATHCFIDYPKKEDYIV 74 Query: 87 VLGAHVLSTAEPTQQVFGIDALTTHPDY--HPMTHANDICLLRLNGSAVLGPAVGLLRPP 144 LG L++ + F ++ L H DY + H NDI LL++ G P Sbjct: 75 YLGRSRLNSNTQGEMKFEVENLILHKDYSADTLAHHNDIALLKIRSKE------GRCAQP 128 Query: 145 GRRAR---------PPTAGTRCRVAGWGFVSDFEEL-PPGLMEAKVRVLDPDVCNS--SW 192 R + P GT C + G+G + + L P L V+++ C + Sbjct: 129 SRTIQTISLPSMYNDPQFGTSCEITGFGKENSTDYLYPEQLKMTVVKLISHRECQQPHYY 188 Query: 193 KGHLTLTMLCTRSGDSHRRGFCSADSGGPLVC----RNRAHGLVSFSGLWCGDPKTPDVY 248 +T MLC + + C DSGGPLVC R G+VS+ G C P VY Sbjct: 189 GSEVTTKMLCA-ADPQWKTDSCQGDSGGPLVCSLQGRMTLTGIVSW-GRGCALKDKPGVY 246 Query: 249 TQVSAFVAWI 258 T+VS F+ WI Sbjct: 247 TRVSHFLPWI 256 >1SI5-H nrPDB Length = 240 Score = 91.3 bits (225), Expect = 5e-19, Method: Compositional matrix adjust. Identities = 64/225 (28%), Positives = 106/225 (47%), Gaps = 20/225 (8%) Query: 47 YMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVL--STAEPTQQVFG 104 +M S+R+ +H CGG L++ WV++A CF RDL+ LG H + E +QV Sbjct: 13 WMVSLRYRNKHICGGSLIKESWVLTARQCFPSRDLKDYEAWLGIHDVHGRGDEKCKQVLN 72 Query: 105 IDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARPPTAGTRCRVAGWGF 164 + L P+ +D+ L++L AVL V + P + P T C V GWG+ Sbjct: 73 VSQLVYGPE------GSDLVLMKLARPAVLDDFVSTIDLPNYGSTIPEK-TSCSVYGWGY 125 Query: 165 --VSDFEELPPGLMEAKVRVLDPDVCNSSWKGHLTL--TMLCTRSGDSHRRGFCSADSGG 220 + +++ L L A + ++ + C+ +G +TL + +C + G C D GG Sbjct: 126 TGLINYDGL---LRVAHLYIMGNEKCSQHHRGKVTLNESEICA-GAEKIGSGPCEGDYGG 181 Query: 221 PLVCRNRAHGL---VSFSGLWCGDPKTPDVYTQVSAFVAWIWDVV 262 PLVC + V G C P P ++ +V+ + WI ++ Sbjct: 182 PLVCEQHKMRMVLGVIVPGRGCAIPNRPGIFVRVAYYAKWIHKII 226 >6AOD-C nrPDB Length = 245 Score = 90.9 bits (224), Expect = 6e-19, Method: Compositional matrix adjust. Identities = 64/213 (30%), Positives = 99/213 (46%), Gaps = 17/213 (7%) Query: 56 QHHCGGFLLRARWVVSAAHCF----SHRDLRTGLVVLGAHVLSTAEPTQQVFGIDALTTH 111 +H CGG ++ +W+++AAHCF S + LR V G S + FG+ + H Sbjct: 26 RHLCGGSIIGNQWILTAAHCFYGVESPKILR---VYSGILQQSEIKEDTSFFGVQEIIIH 82 Query: 112 PDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARPPTAGTRCRVAGWGFVSDFEEL 171 Y DI LL+L + + + P + R T C V GWG+ +++ Sbjct: 83 DQYKMAESGYDIALLKLETTVQYTDSQRPISLPSKGDRNVIY-TDCWVTGWGYRKLRDKI 141 Query: 172 PPGLMEAKVRVLDPDVCNSSWKGH-LTLTMLCT--RSGDSHRRGFCSADSGGPLVCR-NR 227 L +AK+ ++ + C ++GH +T M+C R G + C D+GGPL C+ N Sbjct: 142 QNTLQKAKIPLVTNEECQKRYRGHKITHKMICAGYREGG---KDACKGDAGGPLSCKHNE 198 Query: 228 AHGLVSFS--GLWCGDPKTPDVYTQVSAFVAWI 258 LV + G C + P VYT V +V WI Sbjct: 199 VWHLVGITSWGEGCAQRERPGVYTNVVEYVDWI 231 >5TJX-A nrPDB Length = 263 Score = 90.1 bits (222), Expect = 9e-19, Method: Compositional matrix adjust. Identities = 68/244 (27%), Positives = 111/244 (45%), Gaps = 12/244 (4%) Query: 32 AQIIGGHEVTPHSRPYMAS--VRFGGQHH-CGGFLLRARWVVSAAHCFSHRDLR-TGLVV 87 +I+GG E + P+ S V+ Q H CGG L+ +WV++AAHCF L+ + Sbjct: 14 TRIVGGTESSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIY 73 Query: 88 LGAHVLSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRR 147 G LS I + H +Y +DI L++L + P + Sbjct: 74 SGILELSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLEYTEFQKPISLPS-K 132 Query: 148 ARPPTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWKGH-LTLTMLCTRSG 206 T T C V GWGF + E+ L + + ++ + C ++ + +T M+C Sbjct: 133 GDTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYK 192 Query: 207 DSHRRGFCSADSGGPLVCRN----RAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVV 262 + + C DSGGPLVC++ R G+ S+ G C + P VYT+V+ ++ WI + Sbjct: 193 EGGKDA-CKGDSGGPLVCKHNGMWRLVGITSW-GEGCARREQPGVYTKVAEYMDWILEKT 250 Query: 263 RRSS 266 + S Sbjct: 251 QSSD 254 >2F83-A nrPDB Length = 625 Score = 89.4 bits (220), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 73/270 (27%), Positives = 118/270 (43%), Gaps = 27/270 (10%) Query: 4 GLRGWGRPLLTVATALMLPVKPPAGSWGAQIIGGHEVTPHSRPYMASVRFGG---QHHCG 60 G+ G+ L + +KP +I+GG P+ ++ +H CG Sbjct: 365 GISGYTLRLCKMDNECTTKIKP-------RIVGGTASVRGEWPWQVTLHTTSPTQRHLCG 417 Query: 61 GFLLRARWVVSAAHCF----SHRDLRTGLVVLGAHVLSTAEPTQQVFGIDALTTHPDYHP 116 G ++ +W+++AAHCF S + LR +L S + FG+ + H Y Sbjct: 418 GSIIGNQWILTAAHCFYGVESPKILRVYSGILNQ---SEIKEDTSFFGVQEIIIHDQYKM 474 Query: 117 MTHANDICLLRLNGSAVLGPAVGLLRPPGRRARPPTAGTRCRVAGWGFVSDFEELPPGLM 176 DI LL+L + + + P + R T C V GWG+ +++ L Sbjct: 475 AESGYDIALLKLETTVNYTDSQRPICLPSKGDR-NVIYTDCWVTGWGYRKLRDKIQNTLQ 533 Query: 177 EAKVRVLDPDVCNSSWKGH-LTLTMLCT--RSGDSHRRGFCSADSGGPLVCR-NRAHGLV 232 +AK+ ++ + C ++GH +T M+C R G + C DSGGPL C+ N LV Sbjct: 534 KAKIPLVTNEECQKRYRGHKITHKMICAGYREGG---KDACKGDSGGPLSCKHNEVWHLV 590 Query: 233 SFS--GLWCGDPKTPDVYTQVSAFVAWIWD 260 + G C + P VYT V +V WI + Sbjct: 591 GITSWGEGCAQRERPGVYTNVVEYVDWILE 620 >5XW8-A nrPDB Length = 133 Score = 89.0 bits (219), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 49/131 (37%), Positives = 70/131 (53%), Gaps = 8/131 (6%) Query: 33 QIIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHV 92 +I+GG+ +S PY S+ G H CGG L+ ++WVVSAAHC+ R V LG H Sbjct: 8 KIVGGYTCAANSIPYQVSLN-SGSHFCGGSLINSQWVVSAAHCYKSRI----QVRLGEHN 62 Query: 93 LSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARPPT 152 + E +Q + THP+++ T NDI L++L+ A L V + P A Sbjct: 63 IDVLEGNEQFINAAKIITHPNFNGNTLDNDIMLIKLSSPATLNSRVATVSLPRSCA---A 119 Query: 153 AGTRCRVAGWG 163 AGT C ++GWG Sbjct: 120 AGTECLISGWG 130 >4LK4-A nrPDB Length = 357 Score = 88.2 bits (217), Expect = 4e-18, Method: Compositional matrix adjust. Identities = 68/219 (31%), Positives = 101/219 (46%), Gaps = 26/219 (11%) Query: 53 FGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVLSTAEPTQQVFGIDALTTHP 112 + GQ CGG L R+V++AAHCF R + V++GA+ L+ + +++ + H Sbjct: 36 YQGQF-CGGSFLGGRYVLTAAHCFDSRSAASVDVIIGAYDLNNSSQGERI-AAQKIYRHL 93 Query: 113 DYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARPPTAGTRCRVAGWGFVSDFE--E 170 Y P NDI ++ L ++ L PA+ L P R + P A T VAGWG + + Sbjct: 94 SYSPSNLLNDIAIVELAQTSSL-PAITLAGPATRTSLP--ALTPLTVAGWGITVQSKPPQ 150 Query: 171 LPPGLMEAKVRVLDPDVCNSSWKGHLTLTMLCTRSGDSHRRGFCSA---------DSGGP 221 P L E V ++ +C + M S D + FC+A D+GGP Sbjct: 151 FTPILQEVDVDLVSQSLCQ--------IVMQHGISSDPNSTNFCAARLTKDSCQGDAGGP 202 Query: 222 LVCRN--RAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWI 258 +V + G+VS+ C T VYT VS F WI Sbjct: 203 IVVKTGREQLGIVSWGDEQCAKTGTYGVYTNVSYFRDWI 241 >2ASU-B nrPDB Length = 234 Score = 88.2 bits (217), Expect = 4e-18, Method: Compositional matrix adjust. Identities = 77/241 (31%), Positives = 109/241 (45%), Gaps = 26/241 (10%) Query: 34 IIGGHEVTPHSRPYMASVRF-GGQHHCGGFLLRARWVVSAAHCFS--HRDLRTGLVVLGA 90 ++GGH P + P+ S+R GQH CGG L++ +W+++A CFS H L V LG Sbjct: 1 VVGGH---PGNSPWTVSLRNRQGQHFCGGSLVKEQWILTARQCFSSCHMPLTGYEVWLGT 57 Query: 91 HVLS--TAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLL-RPPGRR 147 + EP+ Q + + P + + LL+L S L V L+ PP Sbjct: 58 LFQNPQHGEPSLQRVPVAKMVCGPS------GSQLVLLKLERSVTLNQRVALICLPPEWY 111 Query: 148 ARPPTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWKGHLTLTMLCTRSGD 207 PP GT+C +AGWG L A + V+ CN +G + + +CT G Sbjct: 112 VVPP--GTKCEIAGWGETKGTGN-DTVLNVALLNVISNQECNIKHRGRVRESEMCTE-GL 167 Query: 208 SHRRGFCSADSGGPLVCRNRAHGLVSFSGLW-----CGDPKTPDVYTQVSAFVAWIWDVV 262 G C D GGPL C H G+ C + P V+T+VS FV WI V+ Sbjct: 168 LAPVGACEGDYGGPLAC--FTHNSWVLEGIIIPNRVCARSRWPAVFTRVSVFVDWIHKVM 225 Query: 263 R 263 R Sbjct: 226 R 226 >2F91-A nrPDB Length = 237 Score = 87.8 bits (216), Expect = 5e-18, Method: Compositional matrix adjust. Identities = 70/237 (29%), Positives = 106/237 (44%), Gaps = 17/237 (7%) Query: 34 IIGGHEVTPHSRPYMASVR--FGGQ--HHCGGFLLRARWVVSAAHCFSHRDLR--TGL-V 86 I+GG + T PY S + F G H CG + + ++A HC D +GL + Sbjct: 1 IVGGTDATLGEFPYQLSFQETFIGFSFHFCGASIYNENYAITAGHCVYGDDYENPSGLQI 60 Query: 87 VLGAHVLSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGR 146 V G +S E ++Q+ + + H ++ NDI LL+L+GS V + P Sbjct: 61 VAGELDMSVNEGSEQIITVSKIILHENFDYNLLDNDISLLKLSGSLTFNDNVAPIALP-- 118 Query: 147 RARPPTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWKGHLTL-TMLCTRS 205 + TA V GWG S+ P L + V ++ + C + + L +M+C Sbjct: 119 -EQGHTATGDVIVTGWGTTSEGGNTPDVLQKVTVPLVSDEDCRADYGADEILDSMICAGV 177 Query: 206 GDSHRRGFCSADSGGPLVCRNRAH----GLVSFSGLWCGDPKTPDVYTQVSAFVAWI 258 + + C DSGGPL + G+VS+ G C P P VYT+VS V WI Sbjct: 178 PEGGKDS-CQGDSGGPLAASDTGSTYLAGIVSW-GYGCARPGYPGVYTEVSYHVDWI 232 >5GVT-A nrPDB Length = 250 Score = 86.7 bits (213), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 69/245 (28%), Positives = 111/245 (45%), Gaps = 20/245 (8%) Query: 34 IIGGHEVTPHSRPYMAS--VRFGGQHH-CGGFLLRARWVVSAAHCFSHRDLRTGLVVLGA 90 I+GG + P+ S V+ Q H CGG ++ +WV++AAHCF + G Sbjct: 1 IVGGTNASLGEWPWQVSLQVKLVSQTHLCGGSIIGRQWVLTAAHCFDGIPYPDVWRIYGG 60 Query: 91 HVLSTAEPTQQV--FGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRA 148 +LS +E T++ I L H +Y DI L++L + P +A Sbjct: 61 -ILSLSEITKETPSSRIKELIIHQEYKVSEGNYDIALIKLQTPLNYTEFQKPISLPS-KA 118 Query: 149 RPPTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWKGH-LTLTMLCTRSGD 207 T T C V GWG+ + E L +A + ++ + C ++ + + M+C Sbjct: 119 DTNTIYTNCWVTGWGYTKEQGETQNILQKATIPLVPNEECQKKYRDYVINKQMICA---- 174 Query: 208 SHRRG---FCSADSGGPLVCRNRAH----GLVSFSGLWCGDPKTPDVYTQVSAFVAWIWD 260 ++ G C DSGGPLVC++ G+ S+ G C P VYT+VS ++ WI + Sbjct: 175 GYKEGGTDACKGDSGGPLVCKHSGRWQLVGITSW-GEGCARKDQPGVYTKVSEYMDWILE 233 Query: 261 VVRRS 265 + S Sbjct: 234 KTQSS 238 >5KWM-A nrPDB Length = 230 Score = 85.5 bits (210), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 68/222 (30%), Positives = 97/222 (43%), Gaps = 9/222 (4%) Query: 34 IIGGHEVTPHSRPY-MASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHV 92 I+GG + P+ +A V GQ CGG L VV+AAHC VV G V Sbjct: 1 IVGGEDANVQDHPFTVALVTPDGQQFCGGTLAAPNKVVTAAHCTVGSQPADINVVSGRTV 60 Query: 93 LSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARPPT 152 +S+ E T V + + HP+Y D+ +L L P + L + P T Sbjct: 61 MSSNEGT--VSKVTNVWVHPEYQDAAKGFDVSVLTLEAPVKEAP-IELAKADDAGYAPDT 117 Query: 153 AGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWKGHLTLTMLCTRSGDSHRRG 212 A T + GWG S+ + L +A V V D C ++ + M+C + Sbjct: 118 AAT---ILGWGNTSEGGQQADHLQKATVPVNSDDTCKQAYGEYTPDAMVCAGVPEGGVD- 173 Query: 213 FCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAF 254 C DSGGP+V N+ G+ S+ G C P P VY +V A+ Sbjct: 174 TCQGDSGGPMVVNNKLIGVTSW-GEGCARPGKPGVYARVGAY 214 >1YM0-A nrPDB Length = 238 Score = 85.5 bits (210), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 65/242 (26%), Positives = 108/242 (44%), Gaps = 14/242 (5%) Query: 34 IIGGHEVTPHSRPYMASVR--FGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAH 91 I+GG E P+ P+ SVR H CGG ++ RWVV AAHC +V+G H Sbjct: 1 IVGGIEARPYEFPWQVSVRRKSSDSHFCGGSIINDRWVVCAAHCMQGEAPALVSLVVGEH 60 Query: 92 VLSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARPP 151 S A +Q +D++ + +Y P T ND+ +++ + VG + P Sbjct: 61 DSSAASTVRQTHDVDSIFVNENYDPATLENDVSVIKTAVAITFDINVGPICAPDPANDYV 120 Query: 152 TAGTRCRVAGWGFVSDFEELPPGLME-AKVRVLDPDVCNSSWKGHLTL-TMLC-TRSGDS 208 ++C +GWG ++ P ++ + + C++ + M+C T + Sbjct: 121 YRKSQC--SGWGTINSGGVCCPAVLRYVTLNITTNAFCDAVYTSDTIYDDMICATDNTGM 178 Query: 209 HRRGFCSADSGGPLVCRNRAH-----GLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVR 263 R C DSGGPL ++ + G+VS+ G+ C P VY++V WI D + Sbjct: 179 TDRDSCQGDSGGPLSVKDGSGIFSLVGIVSW-GIGCA-SGYPGVYSRVGFHAGWITDTIT 236 Query: 264 RS 265 + Sbjct: 237 NN 238 >5XRF-A nrPDB Length = 242 Score = 85.1 bits (209), Expect = 3e-17, Method: Compositional matrix adjust. Identities = 66/235 (28%), Positives = 109/235 (46%), Gaps = 15/235 (6%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQ---HHCGGFLLRARWVVSAAHCFSHRDLRTGL-VVLG 89 +IGG+E + ++A+ F + C G L+ WV++AAHC+ + GL + LG Sbjct: 7 VIGGNECDTNEHRFLAAF-FTSRPWTFQCAGTLIHEEWVLAAAHCY-----KRGLNIYLG 60 Query: 90 AHVLSTA-EPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRA 148 H S + Q+ + I+ D D+ LL+LN + L + Sbjct: 61 MHNQSIQFDDEQRRYAIEEHYYRCDEKLTKWEKDVVLLKLNKPVSNSTHIAPLS---LPS 117 Query: 149 RPPTAGTRCRVAGWGFVSDFEELPPGLME-AKVRVLDPDVCNSSWKGHLTLTMLCTRSGD 207 PP+ G+ CRV GWG +S +++ P + A + +L+ C + + T L Sbjct: 118 SPPSIGSVCRVMGWGIMSSTKDILPDVPHCANINLLNYMECVAHYPDVPETTRLLCAGVL 177 Query: 208 SHRRGFCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVV 262 C+ DSGGPL+C + G+V F C P P +YT+VS + WI +++ Sbjct: 178 EGGIDTCNQDSGGPLICDGQFQGIVFFGKYPCAQPNKPGLYTRVSNYNDWIQNII 232 >1EQ9-A nrPDB Length = 222 Score = 85.1 bits (209), Expect = 3e-17, Method: Compositional matrix adjust. Identities = 68/231 (29%), Positives = 99/231 (42%), Gaps = 21/231 (9%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHV- 92 I+GG + PY S+R G H CG +L V++AAHC D + L L HV Sbjct: 1 IVGGKDAPVGKYPYQVSLRLSGSHRCGASILDNNNVLTAAHCV---DGLSNLNRLKVHVG 57 Query: 93 LSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARPPT 152 + + V+ ++ + +Y ND+ L+ L L++P Sbjct: 58 TNYLSESGDVYDVEDAVVNKNYDDFLLRNDVALVHLTNPIKFND---LVQPIKLSTNDED 114 Query: 153 AGTR-CRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCN-SSWKGHLTLTMLCTRSGDSHR 210 + C + GWG P L E ++ V C W+ + + +CT + Sbjct: 115 LESNPCTLTGWGSTRLGGNTPNALQEIELIVHPQKQCERDQWR--VIDSHICTLT--KRG 170 Query: 211 RGFCSADSGGPLVCRNRAHGLVSFSGLWCGDP---KTPDVYTQVSAFVAWI 258 G C DSGGPLV G+VSF G P PDVYT+VS+FV+WI Sbjct: 171 EGACHGDSGGPLVANGAQIGIVSF-----GSPCALGEPDVYTRVSSFVSWI 216 >1BQY-A nrPDB Length = 234 Score = 84.7 bits (208), Expect = 4e-17, Method: Compositional matrix adjust. Identities = 69/236 (29%), Positives = 105/236 (44%), Gaps = 19/236 (8%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVL 93 + GG E + + + CGG L+ WVV+AAHC D ++ G H Sbjct: 1 VFGGDECNINEHRSLVVLFNSNGFLCGGTLINQDWVVTAAHC----DSNNFQLLFGVHSK 56 Query: 94 STAEPTQQVFGIDALTTHPDYHPMTHAN-DICLLRLNGSAVLGPAVGLLRPPGRRARPPT 152 +Q P+ + DI L++L+ S + L + PP+ Sbjct: 57 KILNEDEQTRDPKEKFFCPNRKKDDEVDKDIMLIKLDSSVSNSEHIAPLS---LPSSPPS 113 Query: 153 AGTRCRVAGWGFVSDFEELPPGLME-AKVRVLDPDVCNS--SWKGHLTLTMLCT---RSG 206 G+ CR+ GWG +E+ P + A + +LD VC + SW+ + T LC + G Sbjct: 114 VGSVCRIMGWGKTIPTKEIYPDVPHCANINILDHAVCRTAYSWR-QVANTTLCAGILQGG 172 Query: 207 DSHRRGFCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVV 262 R C DSGGPL+C G+VS+ G CG P P VYT+V ++ WI ++ Sbjct: 173 ----RDTCHFDSGGPLICNGIFQGIVSWGGHPCGQPGEPGVYTKVFDYLDWIKSII 224 >2XXL-A nrPDB Length = 408 Score = 84.0 bits (206), Expect = 7e-17, Method: Compositional matrix adjust. Identities = 75/281 (26%), Positives = 115/281 (40%), Gaps = 42/281 (14%) Query: 33 QIIGGHEVTPHSRPYMASVRFG----GQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVL 88 ++ G+EV SRP+MA +R+ + CGG ++ R++++AAHC + L Sbjct: 118 RVSNGYEVKLSSRPWMALLRYQQFGESRFLCGGAMISERYILTAAHCVHGLQNDLYEIRL 177 Query: 89 GAHVLSTAEPTQQV------------FGIDALTTHPDYHPMTHANDICLLRLNGSAVLGP 136 G H +ST E +Q GI+ H Y +DI LL+LN S Sbjct: 178 GEHRISTEEDCRQQGRKKKCAPPVVNVGIEKHLIHEKYDARHIMHDIALLKLNRSVPFQK 237 Query: 137 AVGLLRPPGRRARPPTAG--TRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWKG 194 + + P A + V GWG + L++A V + C+ +++ Sbjct: 238 HIKPICLPITDELKEKAEQISTYFVTGWGTTENGSS-SDVLLQANVPLQPRSACSQAYRR 296 Query: 195 HLTLTMLCTRSGDSHRRGFCSADSGGPLVC----------RNRAHGLVSFSGLWCGDPKT 244 + L+ LC GD + C DSGGPL + G+VS + CG Sbjct: 297 AVPLSQLCVGGGD--LQDSCKGDSGGPLQAPAQYLGEYAPKMVEFGIVSQGVVTCGQISL 354 Query: 245 PDVYTQVSAFVAWIWDVVRRS-----------SPQPGPLPG 274 P +YT V +V WI D + + P P PL G Sbjct: 355 PGLYTNVGEYVQWITDTMASNGLLESRGPFEGKPIPNPLLG 395 >6I44-A nrPDB Length = 627 Score = 84.0 bits (206), Expect = 8e-17, Method: Compositional matrix adjust. Identities = 66/243 (27%), Positives = 112/243 (46%), Gaps = 12/243 (4%) Query: 32 AQIIGGHEVTPHSRPYMAS--VRFGGQHH-CGGFLLRARWVVSAAHCFSHRDLR-TGLVV 87 +I+GG + + P+ S V+ Q H CGG L+ +WV++AAHCF L+ + Sbjct: 378 TRIVGGTQSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIY 437 Query: 88 LGAHVLSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRR 147 G LS I + H +Y +DI L++L + P + Sbjct: 438 SGILQLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLQYTEFQKPICLPS-K 496 Query: 148 ARPPTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWKGH-LTLTMLCTRSG 206 T T C V GWGF ++ E+ L + + ++ + C ++ + +T M+C Sbjct: 497 GDTSTIYTNCWVTGWGFSAEAGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYK 556 Query: 207 DSHRRGFCSADSGGPLVCRN----RAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVV 262 + + C D+GGPLVC++ R G+ S+ G C + P VYT+V+ ++ WI + Sbjct: 557 EGGKDA-CKGDAGGPLVCKHNGMWRLVGITSW-GEGCARREQPGVYTKVAEYMDWILEKT 614 Query: 263 RRS 265 + S Sbjct: 615 QSS 617 >1OP0-A nrPDB Length = 234 Score = 82.4 bits (202), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 66/230 (28%), Positives = 103/230 (44%), Gaps = 15/230 (6%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVL 93 +IGG+E + ++ + CGG L+ WVV+AAHC S D + L V VL Sbjct: 1 VIGGNECDINEHRFLVAFFNTTGFFCGGTLINPEWVVTAAHCDS-TDFQMQLGVHSKKVL 59 Query: 94 STAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARPPTA 153 + E T+ + + DI L++L+ + L + PP+ Sbjct: 60 NEDEQTRNP--KEKFICPNKNNNEVLDKDIMLIKLDKPISNSKHIAPLS---LPSSPPSV 114 Query: 154 GTRCRVAGWGFVSDFEELPPGL-MEAKVRVLDPDVCNSSWKGHL----TLTMLCTRSGDS 208 G+ CR+ GWG ++ +E P + A + +LD VC + + L TL + G Sbjct: 115 GSVCRIMGWGSITPVKETFPDVPYCANINLLDHAVCQAGYPELLAEYRTLCAGIVQGG-- 172 Query: 209 HRRGFCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWI 258 + C DSGGPL+C + G+VS+ CG P +YT V + WI Sbjct: 173 --KDTCGGDSGGPLICNGQFQGIVSYGAHPCGQGPKPGIYTNVFDYTDWI 220 >1M9U-A nrPDB Length = 241 Score = 79.3 bits (194), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 75/242 (30%), Positives = 111/242 (45%), Gaps = 18/242 (7%) Query: 34 IIGGHEVTPHSRPY-MASVRFGGQ--HHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGA 90 +IGG +P P+ ++ R G H CG LL + +SA+HC V+ G Sbjct: 1 VIGGTNASPGEFPWQLSQQRQSGSWSHSCGASLLSSTSALSASHCVDGVLPNNIRVIAGL 60 Query: 91 HVLSTAEPTQQVFGIDALTTHPDYHPMT--HANDICLLRLNGSAVLGPAVGLLRPPGRRA 148 S TQ +D+ T H +Y T ++NDI +L L S LG + P Sbjct: 61 WQQSDTSGTQTA-NVDSYTMHENYGAGTASYSNDIAILHLATSISLGGNIQAAVLPANN- 118 Query: 149 RPPTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWKG----HLTLTMLCTR 204 AGT C ++GWG LP L ++ + V+ C ++ G ++ +C + Sbjct: 119 NNDYAGTTCVISGWGRTDGTNNLPDILQKSSIPVITTAQCTAAMVGVGGANIWDNHICVQ 178 Query: 205 SGDSHRRGFCSADSGGPLVCRN---RAHGLVSF---SGLWCGDPKTPDVYTQVSAFVAWI 258 + G C+ DSGGPL C + R G+ S+ SGL P P VYT+VSA++ WI Sbjct: 179 D-PAGNTGACNGDSGGPLNCPDGGTRVVGVTSWVVSSGLGACLPDYPSVYTRVSAYLGWI 237 Query: 259 WD 260 D Sbjct: 238 GD 239 >1PQ7-A nrPDB Length = 224 Score = 79.0 bits (193), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 67/228 (29%), Positives = 102/228 (44%), Gaps = 11/228 (4%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVL 93 I+GG + P++ S+ G CGG LL A V++AAHC S ++G + + Sbjct: 1 IVGGTSASAGDFPFIVSISRNGGPWCGGSLLNANTVLTAAHCVSGY-AQSGFQIRAGSLS 59 Query: 94 STAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARPPTA 153 T+ + ++ HP Y + ND+ +L+L+ S G +G R P A Sbjct: 60 RTSGGITS--SLSSVRVHPSYSG--NNNDLAILKLSTSIPSGGNIGYARLA-ASGSDPVA 114 Query: 154 GTRCRVAGWGFVSD-FEELPPGLMEAKVRVLDPDVCNSSW-KGHLTLTMLCTRSGDSHRR 211 G+ VAGWG S+ P L++ V ++ C + + +T M C S + Sbjct: 115 GSSATVAGWGATSEGGSSTPVNLLKVTVPIVSRATCRAQYGTSAITNQMFCAGV-SSGGK 173 Query: 212 GFCSADSGGPLV-CRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWI 258 C DSGGP+V N G VS+ G C P VY V A ++I Sbjct: 174 DSCQGDSGGPIVDSSNTLIGAVSW-GNGCARPNYSGVYASVGALRSFI 220 >3F6U-H nrPDB Length = 240 Score = 77.8 bits (190), Expect = 5e-15, Method: Compositional matrix adjust. Identities = 68/213 (31%), Positives = 92/213 (43%), Gaps = 18/213 (8%) Query: 59 CGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVLSTAEPTQQVFGIDALTTHPDYHPMT 118 CG L+ WV++AAHC + LV LG + L E + I + HP+Y T Sbjct: 27 CGAVLIHPSWVLTAAHCMDES--KKLLVRLGEYDLRRWEKWELDLDIKEVFVHPNYSKST 84 Query: 119 HANDICLLRLNGSAVLGPAVGLLRPPGR---RARPPTAGTRCRVAGWGFVSDFEELPPG- 174 NDI LL L A L + + P AG V GWG+ S E+ Sbjct: 85 TDNDIALLHLAQPATLSQTIVPICLPDSGLAERELNQAGQETLVTGWGYHSSREKEAKRN 144 Query: 175 ----LMEAKVRVLDPDVCNSSWKGHLTLTMLCT-RSGDSHRRGFCSADSGGPLVCRNRAH 229 L K+ V+ + C+ ++ MLC GD R+ C DSGGP+V Sbjct: 145 RTFVLNFIKIPVVPHNECSEVMSNMVSENMLCAGILGD--RQDACEGDSGGPMVASFHGT 202 Query: 230 ----GLVSFSGLWCGDPKTPDVYTQVSAFVAWI 258 GLVS+ G CG VYT+VS ++ WI Sbjct: 203 WFLVGLVSW-GEGCGLLHNYGVYTKVSRYLDWI 234 >3S9B-A nrPDB Length = 234 Score = 77.8 bits (190), Expect = 5e-15, Method: Compositional matrix adjust. Identities = 64/239 (26%), Positives = 97/239 (40%), Gaps = 25/239 (10%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQH--HCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAH 91 ++GG E + P++ ++ HC G L+ WV++AAHC D R + LG H Sbjct: 1 VVGGDECNINEHPFLVALYTSASSTIHCAGALINREWVLTAAHC----DRRNIRIKLGMH 56 Query: 92 VLSTAEPTQQVF----GIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRR 147 + +Q+ L T P DI L+RL + + P Sbjct: 57 SKNIRNEDEQIRVPRGKYFCLNTK---FPNGLDKDIMLIRLRRPVTYSTHIAPVSLP--- 110 Query: 148 ARPPTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSW----KGHLTLTMLCT 203 +R G+RCR+ GWG +S P + ++ C + TL Sbjct: 111 SRSRGVGSRCRIMGWGKIST-TTYPDVPHCTNIFIVKHKWCEPLYPWVPADSRTLCAGIL 169 Query: 204 RSGDSHRRGFCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVV 262 + G R C DSGGPL+C HG+V+ CG P VYT+V + WI ++ Sbjct: 170 KGG----RDTCHGDSGGPLICNGEMHGIVAGGSEPCGQHLKPAVYTKVFDYNNWIQSII 224 >2OCV-B nrPDB Length = 259 Score = 77.0 bits (188), Expect = 9e-15, Method: Compositional matrix adjust. Identities = 65/231 (28%), Positives = 107/231 (46%), Gaps = 31/231 (13%) Query: 59 CGGFLLRARWVVSAAHC---------FSHRDLRTGLVVLGAHVLSTAE-PTQQVFGIDAL 108 CG L+ RWV++AAHC F+ DL LV +G H + E +++ ++ + Sbjct: 28 CGASLISDRWVLTAAHCILYPPWDKNFTENDL---LVRIGKHSRTRYERNVEKISMLEKI 84 Query: 109 TTHPDYHPMTHAN-DICLLRLNGSAVLGPAVGLLRPPGRRARPPT--AGTRCRVAGWG-- 163 HP Y+ + + DI LL+L + + P ++ AG + RV GWG Sbjct: 85 YVHPRYNWRENLDRDIALLKLKKPVPFSDYIHPVCLPDKQTVTSLLRAGYKGRVTGWGNL 144 Query: 164 ---FVSDFEELPPGLME-AKVRVLDPDVCNSSWKGHLTLTMLCT--RSGDSHRRGFCSAD 217 + ++ E+ P +++ + +++ VC +S + +T M C + D+ R C D Sbjct: 145 RETWTTNINEIQPSVLQVVNLPIVERPVCKASTRIRITDNMFCAGFKVNDTKRGDACEGD 204 Query: 218 SGGPLVCR----NRAH--GLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVV 262 SGGP V + NR + G+VS+ G C YT V AWI V+ Sbjct: 205 SGGPFVMKSPFNNRWYQMGIVSW-GEGCDRKGKYGFYTHVFRLKAWIQKVI 254 >3S69-A nrPDB Length = 234 Score = 76.6 bits (187), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 62/242 (25%), Positives = 98/242 (40%), Gaps = 31/242 (12%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVL 93 +IGG E + + + C G L+ WV++AAHC D + LG H Sbjct: 1 VIGGDECNINEHRSLVAFFNSTGFFCSGTLINEEWVLTAAHC----DNTNFQMKLGVH-- 54 Query: 94 STAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARPP-- 151 +++V D T +P IC + N VL + L++ R + Sbjct: 55 -----SKKVLNEDEQTRNP------KEKFICPNKKN-DEVLDKDIMLIKLDSRVSNSEHI 102 Query: 152 ----------TAGTRCRVAGWGFVSDFEELPPGL-MEAKVRVLDPDVCNSSWKGHLTLTM 200 + G+ C + GWG ++ + P + A + +LD VC + + LT Sbjct: 103 VPLSLPSSPPSVGSVCHIMGWGSITPIKVTYPDVPYCAYINLLDDAVCQAGYPELLTEYR 162 Query: 201 LCTRSGDSHRRGFCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWD 260 + C DSGGPL+C + G+VSF CG P VYT+V + WI Sbjct: 163 TLCAGILEGGKDTCGGDSGGPLICNGQFQGIVSFGAHPCGQGLKPGVYTKVFDYNHWIQS 222 Query: 261 VV 262 ++ Sbjct: 223 II 224 >1ZJK-A nrPDB Length = 403 Score = 76.3 bits (186), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 72/264 (27%), Positives = 112/264 (42%), Gaps = 29/264 (10%) Query: 21 LPVKPP-----AGSWGAQIIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHC 75 LPV P A + G QI GG + P P+ V G G LL WV++AAH Sbjct: 144 LPVCEPVCGLSARTTGGQIYGGQKAKPGDFPWQ--VLILGGTTAAGALLYDNWVLTAAHA 201 Query: 76 FSHRDLRTGLVVLGAHVLSTAEPTQQVFGIDALTTHPDY-HPMTHANDICLLRLNGSAVL 134 + + + L P +A+ H Y H NDI L++LN V+ Sbjct: 202 VYEQKHDASALDIRMGTLKRLSPHYTQAWSEAVFIHEGYTHDAGFDNDIALIKLNNKVVI 261 Query: 135 GPAVGLLRPPGRRA----RPPTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNS 190 + + P + A R GT +GWG ++ L LM + ++D C + Sbjct: 262 NSNITPICLPRKEAESFMRTDDIGT---ASGWG-LTQRGFLARNLMYVDIPIVDHQKCTA 317 Query: 191 SW------KGHLTLTMLCTRSGDSHRRGFCSADSGGPLVCRNRAH------GLVSFSGLW 238 ++ +G +T MLC +S + C DSGG LV + G+VS+ + Sbjct: 318 AYEKPPYPRGSVTANMLCA-GLESGGKDSCRGDSGGALVFLDSETERWFVGGIVSWGSMN 376 Query: 239 CGDPKTPDVYTQVSAFVAWIWDVV 262 CG+ VYT+V ++ WI +++ Sbjct: 377 CGEAGQYGVYTKVINYIPWIENII 400 >1MKW-K nrPDB Length = 308 Score = 75.9 bits (185), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 68/233 (29%), Positives = 109/233 (46%), Gaps = 31/233 (13%) Query: 59 CGGFLLRARWVVSAAHC---------FSHRDLRTGLVVLGAHVLSTAE-PTQQVFGIDAL 108 CG L+ RWV++AAHC F+ DL LV +G H + E +++ +D + Sbjct: 77 CGASLISDRWVLTAAHCLLYPPWDKNFTVDDL---LVRIGKHSRTRYERKVEKISMLDKI 133 Query: 109 TTHPDYHPMTHAN-DICLLRLNGSAVLGPAVGLLRPPGRR--ARPPTAGTRCRVAGWG-- 163 HP Y+ + + DI LL+L L + + P ++ A+ AG + RV GWG Sbjct: 134 YIHPRYNWKENLDRDIALLKLKRPIELSDYIHPVCLPDKQTAAKLLHAGFKGRVTGWGNR 193 Query: 164 ---FVSDFEELPPGLME-AKVRVLDPDVCNSSWKGHLTLTMLCT--RSGDSHRRGFCSAD 217 + + E+ P +++ + +++ VC +S + +T M C + G+ R C D Sbjct: 194 RETWTTSVAEVQPSVLQVVNLPLVERPVCKASTRIRITDNMFCAGYKPGEGKRGDACEGD 253 Query: 218 SGGPLVCR----NRAH--GLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVRR 264 SGGP V + NR + G+VS+ G C YT V WI V+ R Sbjct: 254 SGGPFVMKSPYNNRWYQMGIVSW-GEGCDRDGKYGFYTHVFRLKKWIQKVIDR 305 >1ETT-H nrPDB Length = 259 Score = 75.5 bits (184), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 68/233 (29%), Positives = 109/233 (46%), Gaps = 31/233 (13%) Query: 59 CGGFLLRARWVVSAAHC---------FSHRDLRTGLVVLGAHVLSTAE-PTQQVFGIDAL 108 CG L+ RWV++AAHC F+ DL LV +G H + E +++ +D + Sbjct: 28 CGASLISDRWVLTAAHCLLYPPWDKNFTVDDL---LVRIGKHSRTRYERKVEKISMLDKI 84 Query: 109 TTHPDYHPMTHAN-DICLLRLNGSAVLGPAVGLLRPPGRR--ARPPTAGTRCRVAGWG-- 163 HP Y+ + + DI LL+L L + + P ++ A+ AG + RV GWG Sbjct: 85 YIHPRYNWKENLDRDIALLKLKRPIELSDYIHPVCLPDKQTAAKLLHAGFKGRVTGWGNR 144 Query: 164 ---FVSDFEELPPGLME-AKVRVLDPDVCNSSWKGHLTLTMLCT--RSGDSHRRGFCSAD 217 + + E+ P +++ + +++ VC +S + +T M C + G+ R C D Sbjct: 145 RETWTTSVAEVQPSVLQVVNLPLVERPVCKASTRIRITDNMFCAGYKPGEGKRGDACEGD 204 Query: 218 SGGPLVCR----NRAH--GLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVRR 264 SGGP V + NR + G+VS+ G C YT V WI V+ R Sbjct: 205 SGGPFVMKSPYNNRWYQMGIVSW-GEGCDRDGKYGFYTHVFRLKKWIQKVIDR 256 >6BQM-A nrPDB Length = 506 Score = 75.1 bits (183), Expect = 3e-14, Method: Compositional matrix adjust. Identities = 69/249 (27%), Positives = 105/249 (42%), Gaps = 29/249 (11%) Query: 32 AQIIGGHEVTPHSRPYMASVRFGGQHH--CGGFLLRARWVVSAAHCFSHRDLRTGLVVLG 89 ++IIGG + T PYM ++ H CGG L R+V++AAHC D G V+LG Sbjct: 9 SRIIGGEQATAGEWPYMVALTARNSSHVFCGGSYLGGRYVLTAAHCVDKEDPAKGDVLLG 68 Query: 90 AHVLSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRAR 149 A ++ +++ + + H Y + NDI +L L + P + Sbjct: 69 AFDMNDVNTAERIH-VRQIYVHNSYITASMGNDIAVLELERDPL--PRRSVQISDSSDFN 125 Query: 150 PPTAGTRCRVAGWGFVS--DFEELPPGLM------------EAKVRVLDPDVCNSSWKGH 195 T + V G+G D E+ P + E K + D D N+ Sbjct: 126 ELTKDSPMTVIGFGNRKEVDGEKSDPATILHQVQVPFVPLPECKTKGSDQDAKNN--YSQ 183 Query: 196 LTLTMLCTRSGDSHRRGFCSADSGGPLVCRN----RAHGLVSFSGLWCGDPKTPDVYTQV 251 LT C S + CS D+GGP+ + + G+VS+ G CG +P VYT + Sbjct: 184 LTNNAFC---AGSFGKDACSGDAGGPIFFDSNNGRKQMGVVSW-GDGCGRANSPGVYTNL 239 Query: 252 SAFVAWIWD 260 S F W+ D Sbjct: 240 SVFNDWLDD 248 >1Q3X-A nrPDB Length = 328 Score = 74.7 bits (182), Expect = 4e-14, Method: Compositional matrix adjust. Identities = 71/264 (26%), Positives = 113/264 (42%), Gaps = 29/264 (10%) Query: 21 LPVKPP-----AGSWGAQIIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHC 75 LPV P A + G +I GG + P P+ + GG G LL WV++AAH Sbjct: 69 LPVCEPVCGLSARTTGGRIYGGQKAKPGDFPWQVLI-LGGTTAAGA-LLYDNWVLTAAHA 126 Query: 76 FSHRDLRTGLVVLGAHVLSTAEPTQQVFGIDALTTHPDY-HPMTHANDICLLRLNGSAVL 134 + + + L P +A+ H Y H NDI L++LN V+ Sbjct: 127 VYEQKHDASALDIRMGTLKRLSPHYTQAWSEAVFIHEGYTHDAGFDNDIALIKLNNKVVI 186 Query: 135 GPAVGLLRPPGRRA----RPPTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNS 190 + + P + A R GT +GWG ++ L LM + ++D C + Sbjct: 187 NSNITPICLPRKEAESFMRTDDIGT---ASGWG-LTQRGFLARNLMYVDIPIVDHQKCTA 242 Query: 191 SW------KGHLTLTMLCTRSGDSHRRGFCSADSGGPLVCRNRAH------GLVSFSGLW 238 ++ +G +T MLC +S + C DSGG LV + G+VS+ + Sbjct: 243 AYEKPPYPRGSVTANMLCA-GLESGGKDSCRGDSGGALVFLDSETERWFVGGIVSWGSMN 301 Query: 239 CGDPKTPDVYTQVSAFVAWIWDVV 262 CG+ VYT+V ++ WI +++ Sbjct: 302 CGEAGQYGVYTKVINYIPWIENII 325 >2HLC-A nrPDB Length = 230 Score = 74.3 bits (181), Expect = 5e-14, Method: Compositional matrix adjust. Identities = 65/233 (27%), Positives = 106/233 (45%), Gaps = 19/233 (8%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQHH----CGGFLLRARWVVSAAHCFSHRDLRTGLVVLG 89 II G+E PY A + Q CGG L+ +W+++AAHC D + +V LG Sbjct: 1 IINGYEAYTGLFPYQAGLDITLQDQRRVWCGGSLIDNKWILTAAHCV--HDAVSVVVYLG 58 Query: 90 AHVLSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRAR 149 + V E V + + +H ++P T+ ND+ L+++ + P G Sbjct: 59 SAVQYEGEA---VVNSERIISHSMFNPDTYLNDVALIKIPHVEYTDNIQPIRLPSGEELN 115 Query: 150 PPTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSW-KGHLTLTMLCTRSGDS 208 V+GWG S+ + + L V+D D C + G + + +C + D Sbjct: 116 NKFENIWATVSGWG-QSNTDTVI--LQYTYNLVIDNDRCAQEYPPGIIVESTICGDTSDG 172 Query: 209 HRRGFCSADSGGPLVC--RNRAHGLVSF-SGLWCGDPKTPDVYTQVSAFVAWI 258 + C DSGGP V +N G+VSF SG C K P +++V++++ WI Sbjct: 173 --KSPCFGDSGGPFVLSDKNLLIGVVSFVSGAGCESGK-PVGFSRVTSYMDWI 222 >3P8G-A nrPDB Length = 241 Score = 73.2 bits (178), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 72/240 (30%), Positives = 98/240 (40%), Gaps = 20/240 (8%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQHH-CGGFLLRARWVVSAAHC------FSHRDLRTGLV 86 ++GG + P+ S+ GQ H CG L+ W+VSAAHC F + D Sbjct: 1 VVGGTDADEGEWPWQVSLHALGQGHICGASLISPNWLVSAAHCYIDDRGFRYSDPTQWTA 60 Query: 87 VLGAHVLST-AEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPG 145 LG H S + P Q + + +HP ++ T DI LL L A V + P Sbjct: 61 FLGLHDQSQRSAPGVQERRLKRIISHPFFNDFTFDYDIALLELEKPAEYSSMVRPICLPD 120 Query: 146 RRARPPTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWKGHLTLTMLCT-- 203 P AG V GWG L + ++RV+ C + +T M+C Sbjct: 121 ASHVFP-AGKAIWVTGWGHTQYGGTGALILQKGEIRVIQQTTCENLLPQQITPRMMCVGF 179 Query: 204 RSGDSHRRGFCSADSGGPLVC-----RNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWI 258 SG C DSGGPL R G+VS+ G C P VYT++ F WI Sbjct: 180 LSGGVDS---CQGDSGGPLSSVEADGRIFQAGVVSW-GDGCAQRNKPGVYTRLPLFRDWI 235 >2PKA-B nrPDB Length = 152 Score = 72.4 bits (176), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 43/150 (28%), Positives = 71/150 (47%), Gaps = 7/150 (4%) Query: 119 HANDICLLRLNGSAVLGPAVGLLRPPGRRARPPTAGTRCRVAGWGFVS---DFEELPPGL 175 +++D+ LLRL A + AV +L P + P G+ C +GWG + D E P + Sbjct: 6 YSHDLMLLRLQSPAKITDAVKVLELPTQE---PELGSTCEASGWGSIEPGPDDFEFPDEI 62 Query: 176 MEAKVRVLDPDVCNSSWKGHLTLTMLCTRSGDSHRRGFCSADSGGPLVCRNRAHGLVSFS 235 ++ +L C + +T +MLC + C DSGGPL+C G+ S+ Sbjct: 63 QCVQLTLLQNTFCADAHPDKVTESMLCAGYLPGGKDT-CMGDSGGPLICNGMWQGITSWG 121 Query: 236 GLWCGDPKTPDVYTQVSAFVAWIWDVVRRS 265 CG P +YT++ ++ WI D + + Sbjct: 122 HTPCGSANKPSIYTKLIFYLDWIDDTITEN 151 >2OLG-A nrPDB Length = 278 Score = 72.4 bits (176), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 75/267 (28%), Positives = 112/267 (41%), Gaps = 47/267 (17%) Query: 33 QIIGGHEVTPHSRPYMASVRFGG-----QHHCGGFLLRARWVVSAAHCFSHRDLRT---- 83 +I+ G + P P+ A + + Q CGG L+ R++V+AAHC + R LR Sbjct: 22 KILNGDDTVPEEFPWTAMIGYKNSSNFEQFACGGSLINNRYIVTAAHCVAGRVLRVVGAL 81 Query: 84 GLVVLGAHVLST----------AEPTQQV-FGIDALTTHPDY--HPMTHANDICLLRLNG 130 V LG +T P + + GI+ HPDY +DI L+RLN Sbjct: 82 NKVRLGEWNTATDPDCYGAVRVCVPDKPIDLGIEETIQHPDYVDGSKDRYHDIALIRLNR 141 Query: 131 SAVLGPAVGLLRP-----PGRRARPPTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDP 185 +RP P + G R V GWG ++ + + V V+ Sbjct: 142 QVEF---TNYIRPVCLPQPNEEVQ---VGQRLTVVGWGR-TETGQYSTIKQKLAVPVVHA 194 Query: 186 DVCNSSWKG---HLTLTMLCTRSGDSHRRGFCSADSGGPLVCRNRAH------GLVSFSG 236 + C ++ + + LC +G + C DSGGPL+ RA+ GLVSF G Sbjct: 195 EQCAKTFGAAGVRVRSSQLC--AGGEKAKDSCGGDSGGPLLAE-RANQQFFLEGLVSF-G 250 Query: 237 LWCGDPKTPDVYTQVSAFVAWIWDVVR 263 CG P +YT+V + WI +R Sbjct: 251 ATCGTEGWPGIYTKVGKYRDWIEGNIR 277 >5O32-I nrPDB Length = 244 Score = 71.2 bits (173), Expect = 4e-13, Method: Compositional matrix adjust. Identities = 64/240 (26%), Positives = 103/240 (42%), Gaps = 25/240 (10%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVL 93 I+GG P+ +++ CGG + W+++AAHC R +T + V+ Sbjct: 1 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCL--RASKTHRYQIWTTVV 58 Query: 94 STAEPTQQ---VFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARP 150 P + + +D + H +Y+ T+ NDI L+ + G P A Sbjct: 59 DWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKD---GNKKDCELPRSIPACV 115 Query: 151 PTA------GTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWKGHL-TLTMLCT 203 P + C V+GWG D E + L +V+++ C+ + M C Sbjct: 116 PWSPYLFQPNDTCIVSGWGREKDNERVFS-LQWGEVKLISN--CSKFYGNRFYEKEMECA 172 Query: 204 RSGDSHRRGFCSADSGGPLVCRNRAH-----GLVSFSGLWCGDPKTPDVYTQVSAFVAWI 258 + D C DSGGPLVC + + G+VS+ G CG P+ P VYT+V+ + WI Sbjct: 173 GTYDGSIDA-CKGDSGGPLVCMDANNVTYVWGVVSW-GENCGKPEFPGVYTKVANYFDWI 230 >3LC3-A nrPDB Length = 235 Score = 71.2 bits (173), Expect = 5e-13, Method: Compositional matrix adjust. Identities = 64/235 (27%), Positives = 98/235 (41%), Gaps = 17/235 (7%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGL---VVLGA 90 ++GG + P P+ + CGG ++ +W+V+AAHC + TG+ VV G Sbjct: 1 VVGGEDAKPGQFPWQVVLNGKVDAFCGGSIVNEKWIVTAAHC-----VETGVKITVVAGE 55 Query: 91 HVLSTAEPTQQVFGIDALTTHPDYHPMT--HANDICLLRLNGSAVLGPAVG-LLRPPGRR 147 H + E T+Q + + H +Y+ + +DI LL L+ VL V + Sbjct: 56 HNIEETEHTEQKRNVIRIIPHHNYNAAINKYNHDIALLELDEPLVLNSYVTPICIADKEY 115 Query: 148 ARPPTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWKGHLTLTMLCTRSGD 207 V+GWG V L +V ++D C S K + M C + Sbjct: 116 TNIFLKFGSGYVSGWGRVFHKGRSALVLQYLRVPLVDRATCLRSTKFTIYNNMFCAGFHE 175 Query: 208 SHRRGFCSADSGGPLVCRNRA----HGLVSFSGLWCGDPKTPDVYTQVSAFVAWI 258 R C DSGGP V G++S+ G C +YT+VS +V WI Sbjct: 176 GGRDS-CQGDSGGPHVTEVEGTSFLTGIISW-GEECAMKGKYGIYTKVSRYVNWI 228 >4FXG-H nrPDB Length = 242 Score = 70.9 bits (172), Expect = 5e-13, Method: Compositional matrix adjust. Identities = 64/246 (26%), Positives = 105/246 (42%), Gaps = 24/246 (9%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVL 93 I GG + P P+ + GG G LL WV++AAH + + + L Sbjct: 1 IYGGQKAKPGDFPWQVLI-LGGTTAAGA-LLYDNWVLTAAHAVYEQKHDASALDIRMGTL 58 Query: 94 STAEPTQQVFGIDALTTHPDY-HPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRA---- 148 P +A+ H Y H NDI L++LN V+ + + P + A Sbjct: 59 KRLSPHYTQAWSEAVFIHEGYTHDAGFDNDIALIKLNNKVVINSNITPICLPRKEAESFM 118 Query: 149 RPPTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSW------KGHLTLTMLC 202 R GT +GWG ++ L LM + ++D C +++ +G +T MLC Sbjct: 119 RTDDIGT---ASGWG-LTQRGFLARNLMYVDIPIVDHQKCTAAYEKPPYPRGSVTANMLC 174 Query: 203 TRSGDSHRRGFCSADSGGPLVCRNRAH------GLVSFSGLWCGDPKTPDVYTQVSAFVA 256 +S + C D+GG LV + G+VS+ + CG+ VYT+V ++ Sbjct: 175 A-GLESGGKDSCRGDAGGALVFLDSETERWFVGGIVSWGSMNCGEAGQYGVYTKVINYIP 233 Query: 257 WIWDVV 262 WI +++ Sbjct: 234 WIENII 239 >1VR1-H nrPDB Length = 261 Score = 70.9 bits (172), Expect = 6e-13, Method: Compositional matrix adjust. Identities = 70/260 (26%), Positives = 108/260 (41%), Gaps = 42/260 (16%) Query: 30 WGAQIIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHC---------FSHRD 80 W + H +P G + CG L+ RWV++AAHC F+ D Sbjct: 14 WQVMLFAKHRRSP-----------GERFLCGASLISDRWVLTAAHCLLYPPWDKNFTEND 62 Query: 81 LRTGLVVLGAHVLSTAEPT-QQVFGIDALTTHPDYHPMTHAN-DICLLRLNGSAVLGPAV 138 L LV +G H + E +++ ++ + HP Y+ + + DI L++L + Sbjct: 63 L---LVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYI 119 Query: 139 GLLRPPGRR--ARPPTAGTRCRVAGWGFVSDF------EELPPGLMEAKVRVLDPDVCNS 190 + P R A AG + RV GWG + + + P L + +++ VC Sbjct: 120 HPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKD 179 Query: 191 SWKGHLTLTMLCTRSG-DSHRRG-FCSADSGGPLVCR----NRAH--GLVSFSGLWCGDP 242 S + +T M C D +RG C DSGGP V + NR + G+VS+ G C Sbjct: 180 STRIRITDNMFCAYYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSW-GEGCDRD 238 Query: 243 KTPDVYTQVSAFVAWIWDVV 262 YT V WI V+ Sbjct: 239 GKYGFYTHVFRLKKWIQKVI 258 >4E7N-A nrPDB Length = 238 Score = 70.5 bits (171), Expect = 7e-13, Method: Compositional matrix adjust. Identities = 60/239 (25%), Positives = 104/239 (43%), Gaps = 21/239 (8%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQH--HCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAH 91 IIGG E + ++ ++ CGG L+ WV++AAHC ++ R L + Sbjct: 1 IIGGDECNINEHRFLVALYTSRSRTLFCGGTLINQEWVLTAAHC-DRKNFRIKLGMHSKK 59 Query: 92 VLSTAE----PTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRR 147 V + E P ++ F + + DI L+RL+ + Sbjct: 60 VPNEDEQTRVPKEKFFCLSSKNY------TLWDKDIMLIRLDSPVKNSKHIAPFS---LP 110 Query: 148 ARPPTAGTRCRVAGWGFVSDFEELPPGLME-AKVRVLDPDVCNS---SWKGHLTLTMLCT 203 + PP+ G+ CR+ GWG +S E P + + +L+ ++C + ++ T LC Sbjct: 111 SSPPSVGSVCRIMGWGRISPTEGTYPDVPHCVNINLLEYEMCRAPYPEFELPATSRTLCA 170 Query: 204 RSGDSHRRGFCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVV 262 + + C DSGGPL+C + G+ S+ C P P YT+V + WI +++ Sbjct: 171 GILEGGKDT-CKGDSGGPLICNGQFQGIASWGDDPCAQPHKPAAYTKVFDHLDWIENII 228 >3NXP-A nrPDB Length = 424 Score = 69.3 bits (168), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 64/233 (27%), Positives = 101/233 (43%), Gaps = 31/233 (13%) Query: 59 CGGFLLRARWVVSAAHC---------FSHRDLRTGLVVLGAHVLSTAEPT-QQVFGIDAL 108 CG L+ RWV++AAHC F+ DL LV +G H + E +++ ++ + Sbjct: 193 CGASLISDRWVLTAAHCLLYPPWDKNFTENDL---LVRIGKHSRTRYERNIEKISMLEKI 249 Query: 109 TTHPDYHPMTHAN-DICLLRLNGSAVLGPAVGLLRPPGRR--ARPPTAGTRCRVAGWGFV 165 HP Y+ + + DI L++L + + P R A AG + RV GWG + Sbjct: 250 YIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNL 309 Query: 166 SDF------EELPPGLMEAKVRVLDPDVCNSSWKGHLTLTMLCT--RSGDSHRRGFCSAD 217 + + P L + +++ VC S + +T M C + + R C D Sbjct: 310 KETWTANVGKGQPSVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGD 369 Query: 218 SGGPLVCR----NRAH--GLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVRR 264 SGGP V + NR + G+VS+ G C YT V WI V+ + Sbjct: 370 SGGPFVMKSPFNNRWYQMGIVSW-GEGCDRDGKYGFYTHVFRLKKWIQKVIDQ 421 >1X7A-C nrPDB Length = 235 Score = 69.3 bits (168), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 64/237 (27%), Positives = 95/237 (40%), Gaps = 11/237 (4%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVL 93 I+GG P P+ + CGG ++ +WVV+AAHC T VV G + Sbjct: 1 IVGGENAKPGQFPWQVLLNGKIDAFCGGSIINEKWVVTAAHCIEPGVKIT--VVAGEYNT 58 Query: 94 STAEPTQQVFGIDALTTHPDYHPMT--HANDICLLRLNGSAVLGPAVG-LLRPPGRRARP 150 EPT+Q + H Y+ +++DI LL L+ L V + Sbjct: 59 EETEPTEQRRNVIRAIPHHSYNATVNKYSHDIALLELDEPLTLNSYVTPICIADKEYTNI 118 Query: 151 PTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWKGHLTLTMLCTRSGDSHR 210 V+GWG V + L KV ++D C S K + M C + + Sbjct: 119 FLKFGSGYVSGWGRVFNRGRSATILQYLKVPLVDRATCLRSTKFTIYSNMFCAGFHEGGK 178 Query: 211 RGFCSADSGGPLVCRNRA----HGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVR 263 C DSGGP V G++S+ G C +YT+VS +V WI + + Sbjct: 179 DS-CQGDSGGPHVTEVEGTSFLTGIISW-GEECAVKGKYGIYTKVSRYVNWIKEKTK 233 >4NZQ-A nrPDB Length = 557 Score = 68.9 bits (167), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 64/231 (27%), Positives = 100/231 (43%), Gaps = 31/231 (13%) Query: 59 CGGFLLRARWVVSAAHC---------FSHRDLRTGLVVLGAHVLSTAEPT-QQVFGIDAL 108 CG L+ RWV++AAHC F+ DL LV +G H + E +++ ++ + Sbjct: 326 CGASLISDRWVLTAAHCLLYPPWDKNFTENDL---LVRIGKHSRTRYERNIEKISMLEKI 382 Query: 109 TTHPDYHPMTHAN-DICLLRLNGSAVLGPAVGLLRPPGRR--ARPPTAGTRCRVAGWGFV 165 HP Y+ + + DI L++L + + P R A AG + RV GWG + Sbjct: 383 YIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNL 442 Query: 166 SDF------EELPPGLMEAKVRVLDPDVCNSSWKGHLTLTMLCT--RSGDSHRRGFCSAD 217 + + P L + +++ VC S + +T M C + + R C D Sbjct: 443 KETWTANVGKGQPSVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGD 502 Query: 218 SGGPLVCR----NRAH--GLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVV 262 SGGP V + NR + G+VS+ G C YT V WI V+ Sbjct: 503 SGGPFVMKSPFNNRWYQMGIVSW-GEGCDRDGKYGFYTHVFRLKKWIQKVI 552 >3K65-B nrPDB Length = 308 Score = 68.6 bits (166), Expect = 3e-12, Method: Compositional matrix adjust. Identities = 63/231 (27%), Positives = 100/231 (43%), Gaps = 31/231 (13%) Query: 59 CGGFLLRARWVVSAAHC---------FSHRDLRTGLVVLGAHVLSTAEPT-QQVFGIDAL 108 CG L+ RWV++AAHC F+ DL LV +G H + E +++ ++ + Sbjct: 77 CGASLISDRWVLTAAHCLLYPPWDKNFTENDL---LVRIGKHSRTRYERNIEKISMLEKI 133 Query: 109 TTHPDYHPMTHAN-DICLLRLNGSAVLGPAVGLLRPPGRR--ARPPTAGTRCRVAGWGFV 165 HP Y+ + + DI L++L + + P R A AG + RV GWG + Sbjct: 134 YIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNL 193 Query: 166 SDF------EELPPGLMEAKVRVLDPDVCNSSWKGHLTLTMLCT--RSGDSHRRGFCSAD 217 + + P L + +++ VC S + +T M C + + R C D Sbjct: 194 KETWTANVGKGQPSVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGD 253 Query: 218 SGGPLVCR----NRAH--GLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVV 262 +GGP V + NR + G+VS+ G C YT V WI V+ Sbjct: 254 AGGPFVMKSPFNNRWYQMGIVSW-GEGCDRDGKYGFYTHVFRLKKWIQKVI 303 >1C5M-D nrPDB Length = 255 Score = 68.6 bits (166), Expect = 3e-12, Method: Compositional matrix adjust. Identities = 62/232 (26%), Positives = 97/232 (41%), Gaps = 11/232 (4%) Query: 34 IIGGHEVTPHSRPYMAS-VRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHV 92 I+GG E P+ A + + CGG +L ++++AAHC + V +G Sbjct: 1 IVGGQECKDGECPWQALLINEENEGFCGGTILSEFYILTAAHCLYQ--AKRFKVRVGDRN 58 Query: 93 LSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARPPT 152 E + V ++ + H + T+ DI +LRL V P R T Sbjct: 59 TEQEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACLPERDWAEST 118 Query: 153 AGTRCR--VAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWKGHLTLTMLCTRSGDSHR 210 T+ V+G+G + L +V +D + C S +T M C D+ + Sbjct: 119 LMTQKTGIVSGFGRTHEKGRQSTRLKMLEVPYVDRNSCKLSSSFIITQNMFCA-GYDTKQ 177 Query: 211 RGFCSADSGGPLVCRNR----AHGLVSFSGLWCGDPKTPDVYTQVSAFVAWI 258 C DSGGP V R + G+VS+ G C +YT+V+AF+ WI Sbjct: 178 EDACQGDSGGPHVTRFKDTYFVTGIVSW-GEGCARKGKYGIYTKVTAFLKWI 228 >2XRC-A nrPDB Length = 565 Score = 68.2 bits (165), Expect = 4e-12, Method: Compositional matrix adjust. Identities = 64/241 (26%), Positives = 104/241 (43%), Gaps = 25/241 (10%) Query: 33 QIIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHV 92 +I+GG P+ +++ CGG + W+++AAHC R +T + V Sbjct: 321 RIVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCL--RASKTHRYQIWTTV 378 Query: 93 LSTAEPTQQ---VFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRAR 149 + P + + +D + H +Y+ T+ NDI L+ + G P A Sbjct: 379 VDWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKD---GNKKDCELPRSIPAC 435 Query: 150 PPTA------GTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWKGHL-TLTMLC 202 P + C V+GWG D E + L +V+++ C+ + M C Sbjct: 436 VPWSPYLFQPNDTCIVSGWGREKDNERVFS-LQWGEVKLISN--CSKFYGNRFYEKEMEC 492 Query: 203 TRSGDSHRRGFCSADSGGPLVCRNRAH-----GLVSFSGLWCGDPKTPDVYTQVSAFVAW 257 + D C DSGGPLVC + + G+VS+ G CG P+ P VYT+V+ + W Sbjct: 493 AGTYDGSIDA-CKGDSGGPLVCMDANNVTYVWGVVSW-GENCGKPEFPGVYTKVANYFDW 550 Query: 258 I 258 I Sbjct: 551 I 551 >3VGC-B nrPDB Length = 131 Score = 68.2 bits (165), Expect = 4e-12, Method: Compositional matrix adjust. Identities = 43/132 (32%), Positives = 62/132 (46%), Gaps = 5/132 (3%) Query: 34 IIGGHEVTPHSRPYMASVRFG-GQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHV 92 I+ G E P S P+ S++ G H CGG L+ WVV+AAHC + +VV G Sbjct: 1 IVNGEEAVPGSWPWQVSLQDKTGFHFCGGSLINENWVVTAAHC---GVTTSDVVVAGEFD 57 Query: 93 LSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARPPT 152 ++ Q I + + Y+ +T NDI LL+L+ +A V + P + Sbjct: 58 QGSSSEKIQKLKIAKVFKNSKYNSLTINNDITLLKLSTAASFSQTVSAVCLP-SASDDFA 116 Query: 153 AGTRCRVAGWGF 164 AGT C GWG Sbjct: 117 AGTTCVTTGWGL 128 >5TO3-B nrPDB Length = 409 Score = 67.4 bits (163), Expect = 7e-12, Method: Compositional matrix adjust. Identities = 64/233 (27%), Positives = 101/233 (43%), Gaps = 31/233 (13%) Query: 59 CGGFLLRARWVVSAAHC---------FSHRDLRTGLVVLGAHVLSTAE-PTQQVFGIDAL 108 CG L+ RWV++AAHC F+ DL LV +G H + E +++ ++ + Sbjct: 28 CGASLISDRWVLTAAHCLLYPPWDKNFTENDL---LVRIGKHSRTRYERNIEKISMLEKI 84 Query: 109 TTHPDYHPMTHAN-DICLLRLNGSAVLGPAVGLLRPPGRR--ARPPTAGTRCRVAGWGFV 165 HP Y+ + + DI L++L + + P R A AG + RV GWG + Sbjct: 85 YIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNL 144 Query: 166 SDF------EELPPGLMEAKVRVLDPDVCNSSWKGHLTLTMLCT--RSGDSHRRGFCSAD 217 + + P L + +++ VC S + +T M C + + R C D Sbjct: 145 KETWTANVGKGQPSVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGD 204 Query: 218 SGGPLVCR----NRAH--GLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVRR 264 SGGP V + NR + G+VS +G C YT V WI V+ + Sbjct: 205 SGGPFVMKSPFNNRWYQMGIVS-AGAGCDRDGKYGFYTHVFRLKKWIQKVIDQ 256 >2B9L-A nrPDB Length = 394 Score = 65.5 bits (158), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 58/224 (25%), Positives = 91/224 (40%), Gaps = 27/224 (12%) Query: 56 QHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVLSTAEPTQ----QVFGIDALTTH 111 Q CGG L+ V++ AHC + + + A T + Q I + H Sbjct: 161 QLVCGGSLIAPSVVLTGAHCVNSYQSNLDAIKIRAGEWDTLTEKERLPYQERKIRQVIIH 220 Query: 112 PDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARPPTAGTRCRVAGWGFVSDF--- 168 +++P T ND+ LL L+ V +G + P + T C +GWG +F Sbjct: 221 SNFNPKTVVNDVALLLLDRPLVQADNIGTICLP--QQSQIFDSTECFASGWG-KKEFGSR 277 Query: 169 EELPPGLMEAKVRVLDPDVCNSSWKGH-------LTLTMLCTRSGDSHRRGFCSADSGGP 221 L + ++ +D D C + + L T +C +G + C+ D G P Sbjct: 278 HRYSNILKKIQLPTVDRDKCQADLRNTRLGLKFVLDQTFVC--AGGEQGKDTCTGDGGSP 335 Query: 222 LVC-------RNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWI 258 L C R G+V++ G+ CGD P VY V+ F WI Sbjct: 336 LFCPDPRNPSRYMQMGIVAW-GIGCGDENVPGVYANVAHFRNWI 378 >1KIG-H nrPDB Length = 241 Score = 65.5 bits (158), Expect = 3e-11, Method: Compositional matrix adjust. Identities = 64/237 (27%), Positives = 96/237 (40%), Gaps = 11/237 (4%) Query: 34 IIGGHEVTPHSRPYMAS-VRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHV 92 I+GG + P+ A V + CGG +L +V++AAHC T V +G Sbjct: 1 IVGGRDCAEGECPWQALLVNEENEGFCGGTILNEFYVLTAAHCLHQAKRFT--VRVGDRN 58 Query: 93 LSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARPPT 152 E + ++ H + T+ DI +LRL V P + T Sbjct: 59 TEQEEGNEMAHEVEMTVKHSRFVKETYDFDIAVLRLKTPIRFRRNVAPACLPEKDWAEAT 118 Query: 153 AGTRCR--VAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWKGHLTLTMLCTRSGDSHR 210 T+ V+G+G + L L +V +D C S +T M C D+ Sbjct: 119 LMTQKTGIVSGFGRTHEKGRLSSTLKMLEVPYVDRSTCKLSSSFTITPNMFCA-GYDTQP 177 Query: 211 RGFCSADSGGPLVCRNR----AHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVR 263 C DSGGP V R + G+VS+ G C VYT+VS F+ WI +++ Sbjct: 178 EDACQGDSGGPHVTRFKDTYFVTGIVSW-GEGCARKGKFGVYTKVSNFLKWIDKIMK 233 >3I77-A nrPDB Length = 230 Score = 65.1 bits (157), Expect = 4e-11, Method: Compositional matrix adjust. Identities = 64/239 (26%), Positives = 94/239 (39%), Gaps = 20/239 (8%) Query: 34 IIGGHEVTPHSRPYMAS-VRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHV 92 ++GG P+M + + CGG L V++AAHC S T + G V Sbjct: 1 VVGGTRAAQGEFPFMVRLINEENEGFCGGALYAQDIVLTAAHCVSGSGNNTSITATGGVV 60 Query: 93 LSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARPPT 152 + +V L P + T+ D L++L + P + T Sbjct: 61 DLQSSSAVKVRSTKVLQA-PGFTKETYGKDWALIKL---------AQPINQPTLKIATTT 110 Query: 153 AGTR--CRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWKGHLTLT-MLCTRSGDSH 209 A + VAGWG + L++A V + C SS L M+C D+ Sbjct: 111 AYNQGTFTVAGWGANREGGSQQRYLLKANVPFVSDAACRSSSSFILVANEMICAGYPDTG 170 Query: 210 RRGFCSADSGGPLVCRNRAH-----GLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVR 263 C DSGGP+ ++ A G+VS+ G C P P VYT+VS F + I R Sbjct: 171 GVDTCQGDSGGPMFRKDNADEWIQVGIVSW-GYGCARPGYPGVYTEVSTFASAIASAAR 228 >4IW4-E nrPDB Length = 279 Score = 64.7 bits (156), Expect = 4e-11, Method: Compositional matrix adjust. Identities = 73/265 (27%), Positives = 108/265 (40%), Gaps = 39/265 (14%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQHHC-------GGFLLRARWVVSAAHCF-SHRDLRTGL 85 IIGG P P+ A + G LL A W+++AAH S R T + Sbjct: 1 IIGGRNAEPGLFPWQALIVVEDTSRVPNDKWFGSGALLSASWILTAAHVLRSQRRDTTVI 60 Query: 86 VVLGAHV---LSTAEPTQQVFGIDA----LTTHPDYHPMTHANDICLLRLNGSAVLGPAV 138 V HV L + + +++ + HPD++ + +DI L++L LGP V Sbjct: 61 PVSKEHVTVYLGLHDVRDKSGAVNSSAARVVLHPDFNIQNYNHDIALVQLQEPVPLGPHV 120 Query: 139 GLLRPPGRRARPPTAGTRCRVAGWGF----VSDFEELPPG-------LMEAKVRVLDPDV 187 + P P VAGWG V+ E + G L K+ V+ Sbjct: 121 MPVCLPRLEPEGPAPHMLGLVAGWGISNPNVTVDEIISSGTRTLSDVLQYVKLPVVPHAE 180 Query: 188 CNSSWKGH-----LTLTMLCTRSGDSHRRGFCSADSGGPLVC------RNRAHGLVSFSG 236 C +S++ +T M C + + C DSGG V R GLVS+ G Sbjct: 181 CKTSYESRSGNYSVTENMFCAGYYEGGKDT-CLGDSGGAFVIFDDLSQRWVVQGLVSWGG 239 Query: 237 -LWCGDPKTPDVYTQVSAFVAWIWD 260 CG + VYT+VS +V W+W+ Sbjct: 240 PEECGSKQVYGVYTKVSNYVDWVWE 264 >2JET-B nrPDB Length = 128 Score = 63.5 bits (153), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 43/128 (33%), Positives = 58/128 (45%), Gaps = 5/128 (3%) Query: 37 GHEVTPHSRPYMASVRFG-GQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVLST 95 G + P S P+ S++ G H CGG L+ WVV+AAHC + +VV G + Sbjct: 1 GEDAIPGSWPWQVSLQDKTGFHFCGGSLISEDWVVTAAHCGVK---TSDVVVAGEFDQGS 57 Query: 96 AEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARPPTAGT 155 E QV I + +P ++ T NDI LL+L A V + P P GT Sbjct: 58 DEENIQVLKIAQVFKNPKFNMFTVRNDITLLKLATPAQFSETVSAVCLPNVDDDFP-PGT 116 Query: 156 RCRVAGWG 163 C GWG Sbjct: 117 VCATTGWG 124 >3H7O-A nrPDB Length = 228 Score = 62.0 bits (149), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 65/246 (26%), Positives = 112/246 (45%), Gaps = 35/246 (14%) Query: 36 GGHEVTPHSRPYMASVR-FGGQHH--CGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHV 92 GG + P+ +VR + G+ CGG +L +V++AAHC + T ++ + Sbjct: 2 GGEKTDIKQVPWTVAVRTYPGEESLTCGGAILSQWFVLTAAHCVFDQKPETIVIQYESTN 61 Query: 93 LSTAEPTQQVFGIDALTTH---PDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGR--- 146 L +P + D +H Y T NDI +L L+ L GL P + Sbjct: 62 L-WEDPGKS----DPYVSHVYLSFYRQETMENDIAILELSRPLKLD---GLKSKPAKLPD 113 Query: 147 -RARPPTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSW-KGHLTLTMLCTR 204 RP T G+ V+G+G + L A++ V+D D C + + L+L + C + Sbjct: 114 IEFRPKT-GSDVLVSGYGDGQTMDPKDHDLKSAQLTVVDLDECRTKYGPIFLSLQVFCAQ 172 Query: 205 S-GDSHRRGFCSADSGGPLVCRNRAHGLVSFSGLWCGDPK----TPDVYTQVSAFVAWIW 259 G S G D+G P V ++ G+ ++ PK P+V+T+V ++V+WI Sbjct: 173 KVGVSLESG----DAGDPTVQQDTLVGVAAYF------PKRPEGAPEVFTKVGSYVSWIQ 222 Query: 260 DVVRRS 265 D++++ Sbjct: 223 DIIKKK 228 >3BEU-A nrPDB Length = 224 Score = 62.0 bits (149), Expect = 3e-10, Method: Compositional matrix adjust. Identities = 61/237 (25%), Positives = 91/237 (38%), Gaps = 22/237 (9%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVL 93 ++GG P+M + G CGG L V++AAHC S T + G V Sbjct: 1 VVGGTRAAQGEFPFMVRLSMG----CGGALYAQDIVLTAAHCVSGSGNNTSITATGGVVD 56 Query: 94 STAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARPPTA 153 + +V L P + T+ D L++L + P + TA Sbjct: 57 LQSSSAVKVRSTKVLQA-PGFTKETYGKDWALIKL---------AQPINQPTLKIATTTA 106 Query: 154 GTR--CRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWKGHLTLTMLCTRSGDSHRR 211 + VAGWG + L++A V + C SS L + D+ + Sbjct: 107 YNQGTFTVAGWGANREGGSQQRYLLKANVPFVSDAACRSSSSFILVANEMICAGYDTKQE 166 Query: 212 GFCSADSGGPLVCRNRAH-----GLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVR 263 C DSGGP+ ++ A G+VS+ G C VYT+VS F + I R Sbjct: 167 DTCQGDSGGPMFRKDNADEWVQVGIVSW-GEGCARKGKYGVYTEVSTFASAIASAAR 222 >4KKD-A nrPDB Length = 433 Score = 61.6 bits (148), Expect = 4e-10, Method: Compositional matrix adjust. Identities = 72/266 (27%), Positives = 108/266 (40%), Gaps = 39/266 (14%) Query: 33 QIIGGHEVTPHSRPYMASVRFGGQHHC-------GGFLLRARWVVSAAHCF-SHRDLRTG 84 +IIGG P P+ A + G LL A W+++AAH S R T Sbjct: 154 RIIGGRNAEPGLFPWQALIVVEDTSRVPNDKWFGSGALLSASWILTAAHVLRSQRRDTTV 213 Query: 85 LVVLGAHV---LSTAEPTQQVFGIDA----LTTHPDYHPMTHANDICLLRLNGSAVLGPA 137 + V HV L + + +++ + HPD++ + +DI L++L LGP Sbjct: 214 IPVSKEHVTVYLGLHDVRDKSGAVNSSAARVVLHPDFNIQNYNHDIALVQLQEPVPLGPH 273 Query: 138 VGLLRPPGRRARPPTAGTRCRVAGWGF----VSDFEELPPG-------LMEAKVRVLDPD 186 V + P P VAGWG V+ E + G L K+ V+ Sbjct: 274 VMPVCLPRLEPEGPAPHMLGLVAGWGISNPNVTVDEIISSGTRTLSDVLQYVKLPVVPHA 333 Query: 187 VCNSSWKGH-----LTLTMLCTRSGDSHRRGFCSADSGGPLVC------RNRAHGLVSFS 235 C +S++ +T M C + + C DSG V R GLVS+ Sbjct: 334 ECKTSYESRSGNYSVTENMFCAGYYEGGKDT-CLGDSGEAFVIFDDLSQRWVVQGLVSWG 392 Query: 236 G-LWCGDPKTPDVYTQVSAFVAWIWD 260 G CG + VYT+VS +V W+W+ Sbjct: 393 GPEECGSKQVYGVYTKVSNYVDWVWE 418 >1AKS-B nrPDB Length = 98 Score = 58.5 bits (140), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 33/91 (36%), Positives = 46/91 (50%), Gaps = 3/91 (3%) Query: 173 PGLMEA-KVRVLDPDVCNSSWKGHLTLTMLCTRSGDSHRRGFCSADSGGPLVCRNRAHGL 231 P L++ K VL C SS+ G +T M+C + C DSGGP+VC + G+ Sbjct: 7 PSLLQCLKAPVLSNSSCKSSYPGQITGNMICVGFLQGGKDS-CQGDSGGPVVCNGQLQGI 65 Query: 232 VSFSGLWCGDPKTPDVYTQVSAFVAWIWDVV 262 VS+ G C P VYT+V +V WI + Sbjct: 66 VSW-GYGCAQKNKPGVYTKVCNYVNWIQQTI 95 >1GPZ-A nrPDB Length = 399 Score = 56.2 bits (134), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 70/257 (27%), Positives = 106/257 (41%), Gaps = 33/257 (12%) Query: 22 PVKPPAGSWGAQIIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRD- 80 PV P QIIGG + + P+ G+ GG LL RW+++AAH ++ Sbjct: 148 PVNPVEQR--QQIIGGQKAKMGNFPWQVFTNIHGRG--GGALLGDRWILTAAHTLYPKEH 203 Query: 81 ---LRTGLVVLGAHVLSTAEPTQQVFG--IDALTTHPDYHPMTHAN---DICLLRLNGSA 132 L V H + E ++ I ++ HPDY N DI LL L S Sbjct: 204 EAQSNASLDVFLGH--TNVEELMKLGNHPIRRVSVHPDYRQDESYNFEGDIALLELENSV 261 Query: 133 VLGPAVGLLRPPGRRARPPTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSW 192 LGP + + P G V+G+G + E++ L ++ V +P C + Sbjct: 262 TLGPNLLPICLPDNDTF-YDLGLMGYVSGFGVME--EKIAHDLRFVRLPVANPQACENWL 318 Query: 193 KGH-----LTLTMLCTRSGDSHRRGFCSADSGGPLVCRN------RAHGLVSFSGLWCGD 241 +G + M C S ++ C DSGG R+ A G+VS+ G+ C Sbjct: 319 RGKNRMDVFSQNMFCA-GHPSLKQDACQGDSGGVFAVRDPNTDRWVATGIVSW-GIGCS- 375 Query: 242 PKTPDVYTQVSAFVAWI 258 + YT+V +V WI Sbjct: 376 -RGYGFYTKVLNYVDWI 391 >2QY0-B nrPDB Length = 242 Score = 55.5 bits (132), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 66/245 (26%), Positives = 102/245 (41%), Gaps = 31/245 (12%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRD----LRTGLVVLG 89 IIGG + + P+ G+ GG LL RW+++AAH ++ L V Sbjct: 1 IIGGQKAKMGNFPWQVFTNIHGR--GGGALLGDRWILTAAHTLYPKEHEAQSNASLDVFL 58 Query: 90 AHVLSTAEPTQQVFG--IDALTTHPDYHPMTHAN---DICLLRLNGSAVLGPAVGLLRPP 144 H + E ++ I ++ HPDY N DI LL L S LGP + + P Sbjct: 59 GH--TNVEELMKLGNHPIRRVSVHPDYRQDESYNFEGDIALLELENSVTLGPNLLPICLP 116 Query: 145 GRRARPPTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWKGH-----LTLT 199 G V+G+G + E++ L ++ V +P C + +G + Sbjct: 117 DNDTFYDL-GLMGYVSGFGVME--EKIAHDLRFVRLPVANPQACENWLRGKNRMDVFSQN 173 Query: 200 MLCTRSGDSHRRGFCSADSGGPLVCRN------RAHGLVSFSGLWCGDPKTPDVYTQVSA 253 M C S ++ C DSGG R+ A G+VS+ G+ C + YT+V Sbjct: 174 MFCA-GHPSLKQDACQGDSGGVFAVRDPNTDRWVATGIVSW-GIGC--SRGYGFYTKVLN 229 Query: 254 FVAWI 258 +V WI Sbjct: 230 YVDWI 234 >2FMJ-A nrPDB Length = 222 Score = 54.7 bits (130), Expect = 4e-08, Method: Compositional matrix adjust. Identities = 60/237 (25%), Positives = 89/237 (37%), Gaps = 24/237 (10%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVL 93 ++GG P+M + G CGG L V++AAHC S T + G V Sbjct: 1 VVGGTRAAQGEFPFMVRLSMG----CGGALYAQDIVLTAAHCVSGSGNNTSITATGGVVD 56 Query: 94 STAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARPPTA 153 + +V L P Y+ D L++L + P + TA Sbjct: 57 LQSSSAVKVRSTKVLQA-PGYNGT--GKDWALIKL---------AQPINQPTLKIATTTA 104 Query: 154 GTR--CRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWKGHLTLTMLCTRSGDSHRR 211 + VAGWG + L++A V + C S++ L D+ Sbjct: 105 YNQGTFTVAGWGANREGGSQQRYLLKANVPFVSDAACRSAYGNELVANEEICAGYDTGGV 164 Query: 212 GFCSADSGGPLVCRNRAH-----GLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVR 263 C DSGGP+ ++ A G+VS+ G C VYT+VS F + I R Sbjct: 165 DTCQGDSGGPMFRKDNADEWIQVGIVSW-GEGCARKGKYGVYTEVSTFASAIASAAR 220 >2KAI-A nrPDB Length = 80 Score = 54.3 bits (129), Expect = 6e-08, Method: Composition-based stats. Identities = 30/82 (36%), Positives = 42/82 (51%), Gaps = 4/82 (4%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVL 93 IIGG E +S P+ ++ CGG L+ +WV++AAHC + V LG H L Sbjct: 1 IIGGRECEKNSHPWQVAIYHYSSFQCGGVLVNPKWVLTAAHCKND----NYEVWLGRHNL 56 Query: 94 STAEPTQQVFGIDALTTHPDYH 115 E T Q FG+ A HP ++ Sbjct: 57 FENENTAQFFGVTADFPHPGFN 78 >1MD7-A nrPDB Length = 328 Score = 53.9 bits (128), Expect = 8e-08, Method: Compositional matrix adjust. Identities = 65/246 (26%), Positives = 103/246 (41%), Gaps = 31/246 (12%) Query: 33 QIIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRD----LRTGLVVL 88 +IIGG + + P+ G+ GG LL RW+++AAH ++ L V Sbjct: 89 RIIGGQKAKMGNFPWQVFTNIHGRG--GGALLGDRWILTAAHTLYPKEHEAQSNASLDVF 146 Query: 89 GAHVLSTAEPTQQVFG--IDALTTHPDYHPMTHAN---DICLLRLNGSAVLGPAVGLLRP 143 H + E ++ I ++ HPDY N DI LL L S LGP + + Sbjct: 147 LGH--TNVEELMKLGNHPIRRVSVHPDYRQDESYNFEGDIALLELENSVTLGPNLLPICL 204 Query: 144 PGRRARPPTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWKGH-----LTL 198 P G V+G+G + E++ L ++ V +P C + +G + Sbjct: 205 PDNDTF-YDLGLMGYVSGFGVME--EKIAHDLRFVRLPVANPQACENWLRGKNRMDVFSQ 261 Query: 199 TMLCTRSGDSHRRGFCSADSGGPLVCRN------RAHGLVSFSGLWCGDPKTPDVYTQVS 252 M C S ++ C D+GG R+ A G+VS+ G+ C + YT+V Sbjct: 262 NMFCA-GHPSLKQDACQGDAGGVFAVRDPNTDRWVATGIVSW-GIGCS--RGYGFYTKVL 317 Query: 253 AFVAWI 258 +V WI Sbjct: 318 NYVDWI 323 >3H7T-A nrPDB Length = 235 Score = 52.8 bits (125), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 57/243 (23%), Positives = 93/243 (38%), Gaps = 16/243 (6%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVL 93 IIGG + P+ V + CGG +L A +V++AA C T + H Sbjct: 1 IIGGKKSDITKEPWAVGVLVDEKPFCGGSILTANFVITAAQCVDG----TKPSDISIHYG 56 Query: 94 STAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARPPTA 153 S+ T+ + YHP+T N+ ++ L P Sbjct: 57 SSYRTTKGTSVMAKKIYIVRYHPLTMQNNYAVIETEMPIKLDDKTTKKIELPSLLYDPEP 116 Query: 154 GTRCRVAGWGFVSDFE--ELPPGLMEAKVRVLDPDVCNSSWK-----GHLTLTMLCTRSG 206 T V+GWG ++F+ E LMEA V+D C +K ++ + C G Sbjct: 117 DTSVLVSGWG-STNFKSLEYSGDLMEANFTVVDRKSCEEQYKQIEADKYIYDGVFCA-GG 174 Query: 207 DSHRRGFCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVR-RS 265 + D+G P V G+ S+ + + P V+ +V +V I D++ + Sbjct: 175 EYDETYIGYGDAGDPAVQNGTLVGVASY--ISSMPSEFPSVFLRVGYYVLDIKDIISGKV 232 Query: 266 SPQ 268 PQ Sbjct: 233 KPQ 235 >5UBM-A nrPDB Length = 252 Score = 50.1 bits (118), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 63/260 (24%), Positives = 105/260 (40%), Gaps = 39/260 (15%) Query: 33 QIIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHV 92 +IIGG + + P+ F GG L+ WV++AAH R + +G+ Sbjct: 1 RIIGGSDADIKNFPWQV---FFDNPWAGGALINEYWVLTAAHVVEGN--REPTMYVGSTS 55 Query: 93 LSTAEPTQ-QVFGIDALTTHPDYHPM-------THANDICLLRLNGSAVLGPAVGLLRPP 144 + T+ + ++ + + HP + + NDI L+RL +GP V + P Sbjct: 56 VQTSRLAKSKMLTPEHVFIHPGWKLLEVPEGRTNFDNDIALVRLKDPVKMGPTVSPICLP 115 Query: 145 GRRARPP-TAGTRCRVAGWGFVSDFEE----------LPPGLMEAKVRVLDPDVCNSSWK 193 G + G ++GWG + + P +V+V P ++ Sbjct: 116 GTSSDYNLMDGDLGLISGWGRTEKRDRAVRLKAARLPVAPLRKCKEVKVEKPTADAEAY- 174 Query: 194 GHLTLTMLCTRSGDSHRRGFCSADSGGPLVCRN-------RAHGLVSFSGLWCGDPKTPD 246 T M+C +G C DSGG ++ A GLVS+ G CG T Sbjct: 175 -VFTPNMIC--AGGEKGMDSCKGDSGGAFAVQDPNDKTKFYAAGLVSW-GPQCG---TYG 227 Query: 247 VYTQVSAFVAWIWDVVRRSS 266 +YT+V +V WI ++ +S Sbjct: 228 LYTRVKNYVDWIMKTMQENS 247 >4BXW-A nrPDB Length = 423 Score = 50.1 bits (118), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 65/228 (28%), Positives = 96/228 (42%), Gaps = 28/228 (12%) Query: 59 CGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVLSTAEPTQQVFGIDALTTHPDYHPMT 118 CGG +L +V++AAHC + + T VV+G S E T + +D + H + P Sbjct: 196 CGGTILSPIYVLTAAHCIN--ETETISVVVGEIDKSRIE-TGPLLSVDKIYVHKKFVPPQ 252 Query: 119 HANDICLLRLNGSAVLGPAVGLLRPPGRRARP------PTAGTRCRV---AGWGFVSDF- 168 A L + A+ ++ P + + PTA +V +G VS F Sbjct: 253 KAYKFDLAAYD----YDIAIIQMKTPIQFSENVVPACLPTADFANQVLMKQDFGIVSGFG 308 Query: 169 ---EELPPG--LMEAKVRVLDPDVCNSSWKGHLTLTMLCTRSGDSHRRGFCSADSGGPLV 223 E+ P L KV +D C S + +T M C D+ R C DSGGP Sbjct: 309 RIVEKGPKSKTLKVLKVPYVDRHTCMVSSETPITPNMFCA-GYDTLPRDACQGDSGGPHT 367 Query: 224 CRNR----AHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVRRSSP 267 R G+VS SG C YT++S F+ WI ++R+ P Sbjct: 368 TVYRDTHFITGIVS-SGEGCARNGKYGNYTKLSKFIPWIKRIMRQKLP 414 >1ELV-A nrPDB Length = 333 Score = 49.7 bits (117), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 63/260 (24%), Positives = 105/260 (40%), Gaps = 39/260 (15%) Query: 33 QIIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHV 92 +IIGG + + P+ F GG L+ WV++AAH R + +G+ Sbjct: 82 RIIGGSDADIKNFPWQV---FFDNPWAGGALINEYWVLTAAHVVEGN--REPTMYVGSTS 136 Query: 93 LSTAEPTQ-QVFGIDALTTHPDYHPM-------THANDICLLRLNGSAVLGPAVGLLRPP 144 + T+ + ++ + + HP + + NDI L+RL +GP V + P Sbjct: 137 VQTSRLAKSKMLTPEHVFIHPGWKLLAVPEGRTNFDNDIALVRLKDPVKMGPTVSPICLP 196 Query: 145 GRRARPP-TAGTRCRVAGWGFVSDFEE----------LPPGLMEAKVRVLDPDVCNSSWK 193 G + G ++GWG + + P +V+V P ++ Sbjct: 197 GTSSDYNLMDGDLGLISGWGRTEKRDRAVRLKAARLPVAPLRKCKEVKVEKPTADAEAYV 256 Query: 194 GHLTLTMLCTRSGDSHRRGFCSADSGGPLVCRN-------RAHGLVSFSGLWCGDPKTPD 246 T M+C +G C DSGG ++ A GLVS+ G CG T Sbjct: 257 --FTPNMIC--AGGEKGMDSCKGDSGGAFAVQDPNDKTKFYAAGLVSW-GPQCG---TYG 308 Query: 247 VYTQVSAFVAWIWDVVRRSS 266 +YT+V +V WI ++ +S Sbjct: 309 LYTRVKNYVDWIMKTMQENS 328 >1EPT-B nrPDB Length = 82 Score = 49.3 bits (116), Expect = 2e-06, Method: Composition-based stats. Identities = 27/78 (34%), Positives = 39/78 (50%), Gaps = 3/78 (3%) Query: 86 VVLGAHVLSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPG 145 V LG H + E +Q + THP+++ T NDI L++L+ A L V + P Sbjct: 5 VRLGEHNIDVLEGNEQFINAAKIITHPNFNGNTLDNDIMLIKLSSPATLNSRVATVSLPR 64 Query: 146 RRARPPTAGTRCRVAGWG 163 A AGT C ++GWG Sbjct: 65 SCA---AAGTECLISGWG 79 >4J1Y-A nrPDB Length = 397 Score = 48.9 bits (115), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 63/261 (24%), Positives = 104/261 (39%), Gaps = 39/261 (14%) Query: 32 AQIIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAH 91 A+ IGG + + P+ F GG L+ WV++AAH R + +G+ Sbjct: 145 ARAIGGSDADIKNFPWQV---FFDNPWAGGALINEYWVLTAAHVVEGN--REPTMYVGST 199 Query: 92 VLSTAE-PTQQVFGIDALTTHPDYHPM-------THANDICLLRLNGSAVLGPAVGLLRP 143 + T+ ++ + + HP + + NDI L+RL +GP V + Sbjct: 200 SVQTSRLAKSKMLTPEHVFIHPGWKLLEVPEGRTNFDNDIALVRLKDPVKMGPTVSPICL 259 Query: 144 PGRRARPP-TAGTRCRVAGWGFVSDFEE----------LPPGLMEAKVRVLDPDVCNSSW 192 PG + G ++GWG + + P +V+V P ++ Sbjct: 260 PGTSSDYNLMDGDLGLISGWGRTEKRDRAVRLKAARLPVAPLRKCKEVKVEKPTADAEAY 319 Query: 193 KGHLTLTMLCTRSGDSHRRGFCSADSGGPLVCRN-------RAHGLVSFSGLWCGDPKTP 245 T M+C +G C DSGG ++ A GLVS+ G CG T Sbjct: 320 --VFTPNMIC--AGGEKGMDSCKGDSGGAFAVQDPNDKTKFYAAGLVSW-GPQCG---TY 371 Query: 246 DVYTQVSAFVAWIWDVVRRSS 266 +YT+V +V WI ++ +S Sbjct: 372 GLYTRVKNYVDWIMKTMQENS 392 >1BBR-H nrPDB Length = 150 Score = 48.5 bits (114), Expect = 4e-06, Method: Compositional matrix adjust. Identities = 37/118 (31%), Positives = 58/118 (49%), Gaps = 16/118 (13%) Query: 59 CGGFLLRARWVVSAAHC---------FSHRDLRTGLVVLGAHVLSTAE-PTQQVFGIDAL 108 CG L+ RWV++AAHC F+ DL LV +G H + E +++ +D + Sbjct: 28 CGASLISDRWVLTAAHCLLYPPWDKNFTVDDL---LVRIGKHSRTRYERKVEKISMLDKI 84 Query: 109 TTHPDYHPMTHAN-DICLLRLNGSAVLGPAVGLLRPPGRR--ARPPTAGTRCRVAGWG 163 HP Y+ + + DI LL+L L + + P ++ A+ AG + RV GWG Sbjct: 85 YIHPRYNWKENLDRDIALLKLKRPIELSDYIHPVCLPDKQTAAKLLHAGFKGRVTGWG 142 >1RIW-B nrPDB Length = 147 Score = 48.1 bits (113), Expect = 4e-06, Method: Compositional matrix adjust. Identities = 35/122 (28%), Positives = 57/122 (46%), Gaps = 16/122 (13%) Query: 59 CGGFLLRARWVVSAAHC---------FSHRDLRTGLVVLGAHVLSTAEPT-QQVFGIDAL 108 CG L+ RWV++AAHC F+ DL LV +G H + E +++ ++ + Sbjct: 28 CGASLISDRWVLTAAHCLLYPPWDKNFTENDL---LVRIGKHSRTRYERNIEKISMLEKI 84 Query: 109 TTHPDYHPMTHAN-DICLLRLNGSAVLGPAVGLLRPPGRR--ARPPTAGTRCRVAGWGFV 165 HP Y+ + + DI L++L + + P R A AG + RV GWG + Sbjct: 85 YIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNL 144 Query: 166 SD 167 + Sbjct: 145 KE 146 >2JET-C nrPDB Length = 99 Score = 46.2 bits (108), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 29/98 (29%), Positives = 46/98 (46%), Gaps = 8/98 (8%) Query: 170 ELPPGLMEAKVRVLDPDVCNSSWKGHLTLTMLCTRSGDSHRRGFCSADSGGPLVCRNRA- 228 + P L +A + ++ C SW +T M C + C DSGGPLVC+ Sbjct: 4 KTPEKLQQAALPIVSEADCKKSWGSKITDVMTCAGASGVDS---CMGDSGGPLVCQKDGV 60 Query: 229 ---HGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVR 263 G+VS+ C TP VY++V+A + W+ ++ Sbjct: 61 WTLAGIVSWGSGVC-STSTPGVYSRVTALMPWVQQILE 97 >3RU4-E nrPDB Length = 96 Score = 45.1 bits (105), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 32/92 (34%), Positives = 43/92 (46%), Gaps = 10/92 (10%) Query: 172 PPGLMEAKVRVLDPDVCNSSWKGHLTLTMLCT-RSGDSHRRGFCSADSGGPLVCRNRAH- 229 P L +A + +L C W + M+C SG S C DSGGPLVC+ Sbjct: 3 PDRLQQASLPLLSNTNCKKYWGTKIKDAMICAGASGVSS----CMGDSGGPLVCKKNGAW 58 Query: 230 ---GLVSFSGLWCGDPKTPDVYTQVSAFVAWI 258 G+VS+ C TP VY +V+A V W+ Sbjct: 59 TLVGIVSWGSSTC-STSTPGVYARVTALVNWV 89 >1BBR-E nrPDB Length = 109 Score = 38.9 bits (89), Expect = 0.002, Method: Compositional matrix adjust. Identities = 32/104 (30%), Positives = 46/104 (44%), Gaps = 9/104 (8%) Query: 169 EELPPGLMEAKVRVLDPDVCNSSWKGHLTLTMLCT--RSGDSHRRGFCSADSGGPLVCR- 225 E P L + +++ VC +S + +T M C + G+ R C DSGGP V + Sbjct: 4 EVQPSVLQVVNLPLVERPVCKASTRIRITDNMFCAGYKPGEGKRGDACEGDSGGPFVMKS 63 Query: 226 ---NRAH--GLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVRR 264 NR + G+VS+ G C YT V WI V+ R Sbjct: 64 PYNNRWYQMGIVSW-GEGCDRDGKYGFYTHVFRLKKWIQKVIDR 106 >4WJG-C nrPDB Length = 315 Score = 37.0 bits (84), Expect = 0.011, Method: Compositional matrix adjust. Identities = 36/162 (22%), Positives = 64/162 (39%), Gaps = 7/162 (4%) Query: 33 QIIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHV 92 +I+GGH S P+ A + G L+ +W+++ A A Sbjct: 70 RILGGHLDAKGSFPWQAKMVSHHNLTTGATLINEQWLLTTAKNLFLNHSENATAKDIAPT 129 Query: 93 LSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARPPT 152 L+ +Q+ I+ + HP+Y + DI L++L + V + P + Sbjct: 130 LTLYVGKKQLVEIEKVVLHPNYSQV----DIGLIKLKQKVSVNERVMPICLPSKDY--AE 183 Query: 153 AGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWKG 194 G V+GWG ++F + L + V D D C ++G Sbjct: 184 VGRVGYVSGWGRNANF-KFTDHLKYVMLPVADQDQCIRHYEG 224 >4X0L-C nrPDB Length = 259 Score = 36.6 bits (83), Expect = 0.011, Method: Compositional matrix adjust. Identities = 38/164 (23%), Positives = 69/164 (42%), Gaps = 11/164 (6%) Query: 33 QIIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAH--CFSHRDLRTGLVVLGA 90 +I+GGH S P+ A + G L+ +W+++ A +H + T + A Sbjct: 14 RILGGHLDAKGSFPWQAKMVSHHNLTTGATLINEQWLLTTAKNLFLNHSENATAKDI--A 71 Query: 91 HVLSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARP 150 L+ +Q+ I+ + HP+Y + DI L++L + V + P + Sbjct: 72 PTLTLYVGKKQLVEIEKVVLHPNYSQV----DIGLIKLKQKVSVNERVMPICLPSKDY-- 125 Query: 151 PTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWKG 194 G V+GWG ++F + L + V D D C ++G Sbjct: 126 AEVGRVGYVSGWGRNANF-KFTDHLKYVMLPVADQDQCIRHYEG 168 >2OK5-A nrPDB Length = 752 Score = 36.6 bits (83), Expect = 0.013, Method: Compositional matrix adjust. Identities = 48/226 (21%), Positives = 81/226 (35%), Gaps = 47/226 (20%) Query: 43 HSRPYMASVRF----GGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVLSTAEP 98 H +P+ A + G C G ++ +V++AAHCF+ D + V + Sbjct: 476 HKQPWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHCFTVDDKEHSIKV-------SVGG 528 Query: 99 TQQVFGIDALTTHPDYH---------PMTHANDICLLRLNGSAVLGPAVGLLRPP----- 144 ++ I+ + HP+Y+ P + D+ L++L G + + P Sbjct: 529 EKRDLEIEVVLFHPNYNINGKKEAGIPEFYDYDVALIKLKNKLKYGQTIRPICLPCTEGT 588 Query: 145 GRRAR-PPTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWKGH-------- 195 R R PPT + + D + L E K+ + + N KG Sbjct: 589 TRALRLPPTTTCQQQKEELLPAQDIKALFVSEEEKKLTRKEVYIKNGDKKGSCERDAQYA 648 Query: 196 ------------LTLTMLCTRSGDSHRR-GFCSADSGGPLVCRNRA 228 +T LCT + C DSGGPL+ R+ Sbjct: 649 PGYDKVKDISEVVTPRFLCTGGVSPYADPNTCRGDSGGPLIVHKRS 694 >2WIN-I nrPDB Length = 507 Score = 36.6 bits (83), Expect = 0.014, Method: Compositional matrix adjust. Identities = 48/226 (21%), Positives = 81/226 (35%), Gaps = 47/226 (20%) Query: 43 HSRPYMASVRF----GGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVLSTAEP 98 H +P+ A + G C G ++ +V++AAHCF+ D + V + Sbjct: 232 HKQPWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHCFTVDDKEHSIKV-------SVGG 284 Query: 99 TQQVFGIDALTTHPDYH---------PMTHANDICLLRLNGSAVLGPAVGLLRPP----- 144 ++ I+ + HP+Y+ P + D+ L++L G + + P Sbjct: 285 EKRDLEIEVVLFHPNYNINGKKEAGIPEFYDYDVALIKLKNKLKYGQTIRPICLPCTEGT 344 Query: 145 GRRAR-PPTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWKGH-------- 195 R R PPT + + D + L E K+ + + N KG Sbjct: 345 TRALRLPPTTTCQQQKEELLPAQDIKALFVSEEEKKLTRKEVYIKNGDKKGSCERDAQYA 404 Query: 196 ------------LTLTMLCTRSGDSHRR-GFCSADSGGPLVCRNRA 228 +T LCT + C DSGGPL+ R+ Sbjct: 405 PGYDKVKDISEVVTPRFLCTGGVSPYADPNTCRGDSGGPLIVHKRS 450 >1DLE-A nrPDB Length = 298 Score = 36.6 bits (83), Expect = 0.014, Method: Compositional matrix adjust. Identities = 48/226 (21%), Positives = 81/226 (35%), Gaps = 47/226 (20%) Query: 43 HSRPYMASVRF----GGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVLSTAEP 98 H +P+ A + G C G ++ +V++AAHCF+ D + V + Sbjct: 25 HKQPWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHCFTVDDKEHSIKV-------SVGG 77 Query: 99 TQQVFGIDALTTHPDYH---------PMTHANDICLLRLNGSAVLGPAVGLLRPP----- 144 ++ I+ + HP+Y+ P + D+ L++L G + + P Sbjct: 78 EKRDLEIEVVLFHPNYNINGKKEAGIPEFYDYDVALIKLKNKLKYGQTIRPICLPCTEGT 137 Query: 145 GRRAR-PPTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWKGH-------- 195 R R PPT + + D + L E K+ + + N KG Sbjct: 138 TRALRLPPTTTCQQQKEELLPAQDIKALFVSEEEKKLTRKEVYIKNGDKKGSCERDAQYA 197 Query: 196 ------------LTLTMLCTRSGDSHRR-GFCSADSGGPLVCRNRA 228 +T LCT + C DSGGPL+ R+ Sbjct: 198 PGYDKVKDISEVVTPRFLCTGGVSPYADPNTCRGDSGGPLIVHKRS 243 >2HNT-F nrPDB Length = 105 Score = 34.7 bits (78), Expect = 0.047, Method: Compositional matrix adjust. Identities = 29/99 (29%), Positives = 42/99 (42%), Gaps = 9/99 (9%) Query: 172 PPGLMEAKVRVLDPDVCNSSWKGHLTLTMLCT--RSGDSHRRGFCSADSGGPLVCR---- 225 P L + +++ VC S + +T M C + + R C DSGGP V + Sbjct: 3 PSVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFN 62 Query: 226 NRAH--GLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVV 262 NR + G+VS+ G C YT V WI V+ Sbjct: 63 NRWYQMGIVSW-GEGCDRDGKYGFYTHVFRLKKWIQKVI 100 >2I6S-A nrPDB Length = 517 Score = 33.1 bits (74), Expect = 0.13, Method: Compositional matrix adjust. Identities = 12/31 (38%), Positives = 20/31 (64%) Query: 46 PYMASVRFGGQHHCGGFLLRARWVVSAAHCF 76 P+ +++ Q C G L+ +WV++AAHCF Sbjct: 244 PWHVTIKPKSQETCRGALISDQWVLTAAHCF 274 >4KQQ-A nrPDB Length = 564 Score = 30.8 bits (68), Expect = 0.78, Method: Compositional matrix adjust. Identities = 34/134 (25%), Positives = 55/134 (41%), Gaps = 10/134 (7%) Query: 74 HCFSHRDLRTGLVVLGAHVLSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAV 133 +HR+LR L+ GA S + I A+T P Y+P N L +A+ Sbjct: 213 QYLAHRELRNALLENGAKAGSLVIMDVKTGEILAMTNQPTYNPNNRRN------LQPAAM 266 Query: 134 LGPAVGLLRPPGRRARPPTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWK 193 A+ + PG +P + W SD ++ PG ++ R DV +S + Sbjct: 267 RNRAMIDVFEPGSTVKPFSMSAALASGRWK-PSDIVDVYPGTLQIG-RYTIRDVSRNSRQ 324 Query: 194 GHLTLTMLCTRSGD 207 L LT + +S + Sbjct: 325 --LDLTGILIKSSN 336 >2HNT-C nrPDB Length = 70 Score = 30.0 bits (66), Expect = 1.3, Method: Compositional matrix adjust. Identities = 17/42 (40%), Positives = 22/42 (52%), Gaps = 12/42 (28%) Query: 59 CGGFLLRARWVVSAAHC---------FSHRDLRTGLVVLGAH 91 CG L+ RWV++AAHC F+ DL LV +G H Sbjct: 28 CGASLISDRWVLTAAHCLLYPPWDKNFTENDL---LVRIGKH 66 >6DCR-A nrPDB Length = 694 Score = 29.3 bits (64), Expect = 2.2, Method: Compositional matrix adjust. Identities = 20/57 (35%), Positives = 27/57 (47%), Gaps = 2/57 (3%) Query: 139 GLLRPPGRRARPPTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLD--PDVCNSSWK 193 G+ G R R P + R+ VSD ELP ++A V VLD P +S W+ Sbjct: 43 GMTVKAGCRVRVPFGKQQERIGIVVSVSDASELPLNELKAVVEVLDSEPVFTHSVWR 99 >2DWN-A nrPDB Length = 105 Score = 28.5 bits (62), Expect = 3.0, Method: Compositional matrix adjust. Identities = 20/57 (35%), Positives = 27/57 (47%), Gaps = 2/57 (3%) Query: 139 GLLRPPGRRARPPTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLD--PDVCNSSWK 193 G+ G R R P + R+ VSD ELP ++A V VLD P +S W+ Sbjct: 23 GMTVKAGCRVRVPFGKQQERIGIVVSVSDASELPLNELKAVVEVLDSEPVFTHSVWR 79 >3F1S-B nrPDB Length = 283 Score = 28.1 bits (61), Expect = 4.3, Method: Compositional matrix adjust. Identities = 20/76 (26%), Positives = 34/76 (44%), Gaps = 7/76 (9%) Query: 55 GQHHCGGFLLRARWVVSAAHC-FSHRDLRTGLVVLGAHVLSTAEPTQQVFGIDALTTHPD 113 G+ CGG ++R +V++ A C HR+ + V ++ +P + I + H Sbjct: 75 GKDFCGGVIIRENFVLTTAKCSLLHRN----ITVKTYFNRTSQDPL--MIKITHVHVHMR 128 Query: 114 YHPMTHANDICLLRLN 129 Y ND+ LL L Sbjct: 129 YDADAGENDLSLLELE 144 >3H5C-B nrPDB Length = 317 Score = 28.1 bits (61), Expect = 4.5, Method: Compositional matrix adjust. Identities = 20/76 (26%), Positives = 34/76 (44%), Gaps = 7/76 (9%) Query: 55 GQHHCGGFLLRARWVVSAAHC-FSHRDLRTGLVVLGAHVLSTAEPTQQVFGIDALTTHPD 113 G+ CGG ++R +V++ A C HR+ + V ++ +P + I + H Sbjct: 116 GKDFCGGVIIRENFVLTTAKCSLLHRN----ITVKTYFNRTSQDPL--MIKITHVHVHMR 169 Query: 114 YHPMTHANDICLLRLN 129 Y ND+ LL L Sbjct: 170 YDADAGENDLSLLELE 185 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 4Q7Y-A nrPDB 369 e-102 1UTJ-A nrPDB 327 4e-90 1F7Z-A nrPDB 322 1e-88 4AN7-A nrPDB 321 2e-88 5C67-A nrPDB 320 5e-88 4WWY-A nrPDB 319 8e-88 5FXL-A nrPDB 316 8e-87 1A0J-A nrPDB 315 2e-86 2F83-A nrPDB 308 2e-84 1SGF-G nrPDB 307 4e-84 1FXY-A nrPDB 302 1e-82 4NFE-A nrPDB 301 2e-82 1SPJ-A nrPDB 299 1e-81 2TLD-E nrPDB 296 7e-81 3QUM-P nrPDB 294 3e-80 1NPM-A nrPDB 293 7e-80 5MS3-A nrPDB 291 2e-79 6I44-A nrPDB 290 6e-79 2EEK-A nrPDB 289 1e-78 5TJX-A nrPDB 286 5e-78 3E0N-B nrPDB 286 7e-78 1EUF-A nrPDB 286 7e-78 3T2N-A nrPDB 285 2e-77 1AO5-A nrPDB 284 4e-77 1TON-A nrPDB 283 7e-77 1FI8-A nrPDB 283 7e-77 5GVT-A nrPDB 281 2e-76 3BSQ-A nrPDB 281 2e-76 1FDP-A nrPDB 281 2e-76 1SGF-A nrPDB 280 4e-76 4GSO-A nrPDB 280 4e-76 2PSX-A nrPDB 279 8e-76 1P57-B nrPDB 278 2e-75 1GVZ-A nrPDB 278 2e-75 1BRU-P nrPDB 277 5e-75 3W94-A nrPDB 277 5e-75 5ZFH-A nrPDB 276 6e-75 1X7A-C nrPDB 276 7e-75 1KIG-H nrPDB 276 7e-75 6AOD-C nrPDB 275 1e-74 2CGA-A nrPDB 274 3e-74 5FCR-A nrPDB 274 3e-74 6QHB-A nrPDB 274 3e-74 3LC3-A nrPDB 274 4e-74 2AIQ-A nrPDB 274 4e-74 4Z6A-H nrPDB 273 7e-74 1IAU-A nrPDB 273 7e-74 4DGJ-A nrPDB 271 3e-73 1C5M-D nrPDB 271 3e-73 3DFJ-A nrPDB 270 6e-73 5UGG-A nrPDB 270 6e-73 1MKW-K nrPDB 269 7e-73 1EKB-B nrPDB 269 1e-72 4H4F-A nrPDB 268 2e-72 3K65-B nrPDB 268 2e-72 4DUR-A nrPDB 268 2e-72 3NXP-A nrPDB 267 3e-72 1NN6-A nrPDB 267 4e-72 1OP0-A nrPDB 267 5e-72 4NZQ-A nrPDB 266 1e-71 1BQY-A nrPDB 266 1e-71 4E7N-A nrPDB 265 1e-71 4MPW-A nrPDB 265 1e-71 3S69-A nrPDB 265 2e-71 1FUJ-A nrPDB 264 3e-71 3P8G-A nrPDB 263 6e-71 3G01-A nrPDB 263 6e-71 1ETT-H nrPDB 263 6e-71 1PYT-D nrPDB 263 7e-71 2F91-A nrPDB 263 8e-71 1VR1-H nrPDB 262 8e-71 2OCV-B nrPDB 261 2e-70 1BDA-A nrPDB 261 3e-70 2V35-A nrPDB 261 3e-70 1LTO-A nrPDB 261 3e-70 2BDH-A nrPDB 260 5e-70 1FIZ-A nrPDB 260 6e-70 1ORF-A nrPDB 260 7e-70 3TK9-A nrPDB 259 7e-70 2OQ5-A nrPDB 258 2e-69 1MZD-A nrPDB 258 2e-69 1FIW-A nrPDB 257 4e-69 1ELT-A nrPDB 257 4e-69 1Q3X-A nrPDB 256 8e-69 1A5I-A nrPDB 255 1e-68 1YC0-A nrPDB 255 2e-68 1ZJK-A nrPDB 253 5e-68 3S9B-A nrPDB 252 1e-67 2XXL-A nrPDB 252 1e-67 2R0L-A nrPDB 251 2e-67 3RP2-A nrPDB 250 3e-67 4XDE-A nrPDB 250 5e-67 2ZKS-A nrPDB 250 6e-67 5TO3-B nrPDB 249 9e-67 1AZZ-A nrPDB 249 1e-66 3F6U-H nrPDB 249 1e-66 4FXG-H nrPDB 248 2e-66 1KYN-A nrPDB 247 4e-66 5LPF-A nrPDB 246 8e-66 1SC8-U nrPDB 245 2e-65 5LHN-A nrPDB 244 4e-65 2RDL-A nrPDB 243 5e-65 1AE5-A nrPDB 243 5e-65 1FON-A nrPDB 243 7e-65 1YM0-A nrPDB 241 2e-64 4IW4-E nrPDB 239 1e-63 1PPF-E nrPDB 239 1e-63 4KKD-A nrPDB 238 3e-63 4BXW-A nrPDB 237 3e-63 4IGD-A nrPDB 237 3e-63 5XRF-A nrPDB 235 1e-62 4DJZ-B nrPDB 234 4e-62 1EQ9-A nrPDB 230 6e-61 5KWM-A nrPDB 229 1e-60 2XRC-A nrPDB 227 5e-60 1GPZ-A nrPDB 225 1e-59 2QY0-B nrPDB 223 5e-59 1MD7-A nrPDB 223 8e-59 5O32-I nrPDB 222 1e-58 3I77-A nrPDB 220 7e-58 4LK4-A nrPDB 217 3e-57 2OLG-A nrPDB 217 5e-57 6BQM-A nrPDB 216 9e-57 1SI5-H nrPDB 215 2e-56 5UBM-A nrPDB 215 3e-56 2B9L-A nrPDB 214 4e-56 1ELV-A nrPDB 212 2e-55 1PQ7-A nrPDB 210 5e-55 3BEU-A nrPDB 209 1e-54 4J1Y-A nrPDB 207 7e-54 2ASU-B nrPDB 206 7e-54 2FMJ-A nrPDB 202 1e-52 2HLC-A nrPDB 202 2e-52 2PKA-B nrPDB 191 2e-49 1M9U-A nrPDB 191 4e-49 3H7T-A nrPDB 188 2e-48 3H7O-A nrPDB 184 4e-47 5XW8-A nrPDB 181 2e-46 3VGC-B nrPDB 161 2e-40 2JET-B nrPDB 158 3e-39 1RIW-B nrPDB 152 1e-37 1BBR-H nrPDB 150 7e-37 1AKS-B nrPDB 147 6e-36 2KAI-A nrPDB 122 1e-28 3RU4-E nrPDB 112 2e-25 2JET-C nrPDB 109 9e-25 1EPT-B nrPDB 109 2e-24 Sequences not found previously or not previously below threshold: 4X0L-C nrPDB 161 2e-40 4WJG-C nrPDB 161 4e-40 4F4O-C nrPDB 155 2e-38 1BBR-E nrPDB 123 1e-28 2HNT-F nrPDB 120 6e-28 2WIN-I nrPDB 114 4e-26 1DLE-A nrPDB 113 9e-26 2OK5-A nrPDB 111 3e-25 2I6S-A nrPDB 109 2e-24 3F1S-B nrPDB 87 1e-17 3H5C-B nrPDB 85 4e-17 2HNT-E nrPDB 81 4e-16 2HNT-C nrPDB 76 1e-14 1P3E-A nrPDB 49 2e-06 2EA3-A nrPDB 34 0.076 1DUE-A nrPDB 33 0.11 2PFE-A nrPDB 33 0.16 2OUA-A nrPDB 33 0.18 2HRV-A nrPDB 32 0.32 3LT3-A nrPDB 31 0.43 4FVB-A nrPDB 31 0.47 3W95-A nrPDB 31 0.47 2M5T-A nrPDB 31 0.64 2SFA-A nrPDB 31 0.73 4V1Y-A nrPDB 29 1.9 4NSY-A nrPDB 29 2.1 2SGA-A nrPDB 29 2.1 1HPG-A nrPDB 29 2.8 4XZB-A nrPDB 28 4.4 4B6E-A nrPDB 28 6.9 4NWK-A nrPDB 27 8.0 6C2N-A nrPDB 27 8.4 6FE6-A nrPDB 27 9.4 4U01-A nrPDB 27 9.6 >4Q7Y-A nrPDB Length = 250 Score = 369 bits (947), Expect = e-102, Method: Composition-based stats. Identities = 249/250 (99%), Positives = 249/250 (99%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVL 93 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVL Sbjct: 1 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVL 60 Query: 94 STAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARPPTA 153 STAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLR PGRRARPPTA Sbjct: 61 STAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRLPGRRARPPTA 120 Query: 154 GTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWKGHLTLTMLCTRSGDSHRRGF 213 GTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWKGHLTLTMLCTRSGDSHRRGF Sbjct: 121 GTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWKGHLTLTMLCTRSGDSHRRGF 180 Query: 214 CSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVRRSSPQPGPLP 273 CSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVRRSSPQPGPLP Sbjct: 181 CSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVRRSSPQPGPLP 240 Query: 274 GTTRPPGEAA 283 GTTRPPGEAA Sbjct: 241 GTTRPPGEAA 250 >1UTJ-A nrPDB Length = 242 Score = 327 bits (839), Expect = 4e-90, Method: Composition-based stats. Identities = 80/250 (32%), Positives = 118/250 (47%), Gaps = 10/250 (4%) Query: 15 VATALMLPVKPPAGSWGAQIIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAH 74 ++ +L + + +I+GG+E P+S+P+ S+ G H CGG L+ WVVSAAH Sbjct: 2 ISLVFVLLIGAAFATEDDKIVGGYECKPYSQPHQVSLN-SGYHFCGGSLVNENWVVSAAH 60 Query: 75 CFSHRDLRTGLVVLGAHVLSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVL 134 C+ R V LG H + E ++Q + HP+Y NDI L++L+ A L Sbjct: 61 CYKSR----VEVRLGEHNIKVTEGSEQFISSSRVIRHPNYSSYNIDNDIMLIKLSKPATL 116 Query: 135 GPAVGLLRPPGRRARPPTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWKG 194 V + P A AGT C V+GWG L + +L CN+S+ G Sbjct: 117 NTYVQPVALPTSCA---PAGTMCTVSGWGNTMSSTADSNKLQCLNIPILSYSDCNNSYPG 173 Query: 195 HLTLTMLCTRSGDSHRRGFCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAF 254 +T M C + + C DSGGP+VC G+VS+ G C +P P VY +V F Sbjct: 174 MITNAMFCAGYLEGGK-DSCQGDSGGPVVCNGELQGVVSW-GYGCAEPGNPGVYAKVCIF 231 Query: 255 VAWIWDVVRR 264 W+ + Sbjct: 232 NDWLTSTMAS 241 >1F7Z-A nrPDB Length = 233 Score = 322 bits (825), Expect = 1e-88, Method: Composition-based stats. Identities = 79/236 (33%), Positives = 113/236 (47%), Gaps = 11/236 (4%) Query: 31 GAQIIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGA 90 I+GG+ +S PY S+ G H CGG L+ +WVVSAAHC+ R V LG Sbjct: 8 DDAIVGGYTCQENSVPYQVSLN-SGYHFCGGSLINDQWVVSAAHCYKSR----IQVRLGE 62 Query: 91 HVLSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARP 150 H ++ E +Q + HP++ T NDI L++L+ L V + P A Sbjct: 63 HNINVLEGNEQFVNAAKIIKHPNFDRKTLNNDIMLIKLSSPVKLNARVATVALPSSCA-- 120 Query: 151 PTAGTRCRVAGWGFVSDFE-ELPPGLMEAKVRVLDPDVCNSSWKGHLTLTMLCTRSGDSH 209 AGT+C ++GWG P L +L C +S+ G +T M+C + Sbjct: 121 -PAGTQCLISGWGNTLSSGVNEPDLLQCLDAPLLPQADCEASYPGKITDNMVCVGFLEGG 179 Query: 210 RRGFCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVRRS 265 + C DSGGP+VC G+VS+ G C P P VYT+V +V WI D + + Sbjct: 180 K-DSCQGDSGGPVVCNGELQGIVSW-GYGCALPDNPGVYTKVCNYVDWIQDTIAAN 233 >4AN7-A nrPDB Length = 231 Score = 321 bits (824), Expect = 2e-88, Method: Composition-based stats. Identities = 82/236 (34%), Positives = 116/236 (49%), Gaps = 11/236 (4%) Query: 31 GAQIIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGA 90 +I+GG+ +S PY S+ G H CGG L+ ++WVVSAAHC+ R V LG Sbjct: 6 DDKIVGGYTCAANSIPYQVSLN-SGSHFCGGSLINSQWVVSAAHCYKSR----IQVRLGE 60 Query: 91 HVLSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARP 150 H + E +Q + THP+++ T NDI L++L+ A L V + P A Sbjct: 61 HNIDVLEGNEQFINAAKIITHPNFNGNTLDNDIMLIKLSSPATLNSRVATVSLPRSCA-- 118 Query: 151 PTAGTRCRVAGWGFVSDFE-ELPPGLMEAKVRVLDPDVCNSSWKGHLTLTMLCTRSGDSH 209 AGT C ++GWG P L K VL C SS+ G +T M+C + Sbjct: 119 -AAGTECLISGWGNTKSSGSSYPSLLQCLKAPVLSDSSCKSSYPGQITGNMICVGFLEGG 177 Query: 210 RRGFCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVRRS 265 + C DSGGP+VC + G+VS+ G C P VYT+V +V WI + + Sbjct: 178 K-DSCQGDSGGPVVCNGQLQGIVSW-GYGCAQKNKPGVYTKVCNYVNWIQQTIAAN 231 >5C67-A nrPDB Length = 224 Score = 320 bits (820), Expect = 5e-88, Method: Composition-based stats. Identities = 83/234 (35%), Positives = 117/234 (50%), Gaps = 11/234 (4%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVL 93 I+GG+ +S PY S+ G H CGG L+ +WVVSAAHC+ R V LG H + Sbjct: 1 IVGGYTCEENSLPYQVSLN-SGSHFCGGSLISEQWVVSAAHCYKTR----IQVRLGEHNI 55 Query: 94 STAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARPPTA 153 E +Q + HP Y+ T NDI L++L+ AV+ V + P PP A Sbjct: 56 KVLEGNEQFINAAKIIRHPKYNRDTLDNDIMLIKLSSPAVINARVSTISLP---TAPPAA 112 Query: 154 GTRCRVAGWGFVSDFE-ELPPGLMEAKVRVLDPDVCNSSWKGHLTLTMLCTRSGDSHRRG 212 GT C ++GWG F + P L VL C +S+ G +T +M C + + Sbjct: 113 GTECLISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKITNSMFCVGFLEGGK-D 171 Query: 213 FCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVRRSS 266 C D+GGP+VC + G+VS+ G C P VYT+V +V WI D + +S Sbjct: 172 SCQRDAGGPVVCNGQLQGVVSW-GHGCAWKNRPGVYTKVYNYVDWIKDTIAANS 224 >4WWY-A nrPDB Length = 224 Score = 319 bits (818), Expect = 8e-88, Method: Composition-based stats. Identities = 80/234 (34%), Positives = 114/234 (48%), Gaps = 11/234 (4%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVL 93 I+GG+ +S PY S+ G H CGG L+ +WVVSA HC+ R V LG H + Sbjct: 1 IVGGYNCEENSVPYQVSLN-SGYHFCGGSLINEQWVVSAGHCYKSR----IQVRLGEHNI 55 Query: 94 STAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARPPTA 153 E +Q + HP Y T NDI L++L+ AV+ V + P PP Sbjct: 56 EVLEGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVINAHVSTISLP---TAPPAT 112 Query: 154 GTRCRVAGWGFVSDFE-ELPPGLMEAKVRVLDPDVCNSSWKGHLTLTMLCTRSGDSHRRG 212 GT+C ++GWG + + P L VL C +S+ G +T M C + + Sbjct: 113 GTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKITSNMFCVGFLEGGK-D 171 Query: 213 FCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVRRSS 266 C DSGGP+VC + G+VS+ G C P VYT+V +V WI + + +S Sbjct: 172 SCQRDSGGPVVCNGQLQGVVSW-GDGCAQKNKPGVYTKVYNYVKWIKNTIAANS 224 >5FXL-A nrPDB Length = 246 Score = 316 bits (810), Expect = 8e-87, Method: Composition-based stats. Identities = 77/236 (32%), Positives = 114/236 (48%), Gaps = 11/236 (4%) Query: 31 GAQIIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGA 90 +I+GG+ ++ PY S+ G H CGG L+ ++WVVSAAHC+ V LG Sbjct: 21 DDKIVGGYTCGANTVPYQVSLN-SGYHFCGGSLINSQWVVSAAHCYKSG----IQVRLGE 75 Query: 91 HVLSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARP 150 ++ E +Q HP Y+ T NDI L++L +A L V + P A Sbjct: 76 DNINVVEGNEQFISASKSIVHPSYNSNTLNNDIMLIKLKSAASLNSRVASISLPTSCA-- 133 Query: 151 PTAGTRCRVAGWGFVSDFE-ELPPGLMEAKVRVLDPDVCNSSWKGHLTLTMLCTRSGDSH 209 +AGT+C ++GWG P L K +L C S++ G +T M C + Sbjct: 134 -SAGTQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKSAYPGQITSNMFCAGYLEGG 192 Query: 210 RRGFCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVRRS 265 + C DSGGP+VC + G+VS+ G C P VYT+V +V+WI + + Sbjct: 193 K-DSCQGDSGGPVVCSGKLQGIVSW-GSGCAQKNKPGVYTKVCNYVSWIKQTIASN 246 >1A0J-A nrPDB Length = 223 Score = 315 bits (807), Expect = 2e-86, Method: Composition-based stats. Identities = 82/233 (35%), Positives = 119/233 (51%), Gaps = 11/233 (4%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVL 93 I+GG+E +S Y AS++ G H CGG L+ + WVVSAAHC+ R V LG H + Sbjct: 1 IVGGYECRKNSASYQASLQ-SGYHFCGGSLISSTWVVSAAHCYKSR----IQVRLGEHNI 55 Query: 94 STAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARPPTA 153 + E T+Q + HP Y+ NDI L++L+ A L V + P A ++ Sbjct: 56 AVNEGTEQFIDSVKVIMHPSYNSRNLDNDIMLIKLSKPASLNSYVSTVALPSSCA---SS 112 Query: 154 GTRCRVAGWGFVS-DFEELPPGLMEAKVRVLDPDVCNSSWKGHLTLTMLCTRSGDSHRRG 212 GTRC V+GWG +S P L + +L CNS++ G +T M C + + Sbjct: 113 GTRCLVSGWGNLSGSSSNYPDTLRCLDLPILSSSSCNSAYPGQITSNMFCAGFMEGGK-D 171 Query: 213 FCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVRRS 265 C DSGGP+VC + G+VS+ G C P VYT+V + +WI + + Sbjct: 172 SCQGDSGGPVVCNGQLQGVVSW-GYGCAQRNKPGVYTKVCNYRSWISSTMSSN 223 >2F83-A nrPDB Length = 625 Score = 308 bits (790), Expect = 2e-84, Method: Composition-based stats. Identities = 68/270 (25%), Positives = 115/270 (42%), Gaps = 19/270 (7%) Query: 4 GLRGWGRPLLTVATALMLPVKPPAGSWGAQIIGGHEVTPHSRPYMASVRFGG---QHHCG 60 G+ G+ L + +KP +I+GG P+ ++ +H CG Sbjct: 365 GISGYTLRLCKMDNECTTKIKP-------RIVGGTASVRGEWPWQVTLHTTSPTQRHLCG 417 Query: 61 GFLLRARWVVSAAHCFSHRDLRTG-LVVLGAHVLSTAEPTQQVFGIDALTTHPDYHPMTH 119 G ++ +W+++AAHCF + V G S + FG+ + H Y Sbjct: 418 GSIIGNQWILTAAHCFYGVESPKILRVYSGILNQSEIKEDTSFFGVQEIIIHDQYKMAES 477 Query: 120 ANDICLLRLNGSAVLGPAVGLLRPPGRRARPPTAGTRCRVAGWGFVSDFEELPPGLMEAK 179 DI LL+L + + + P + R T C V GWG+ +++ L +AK Sbjct: 478 GYDIALLKLETTVNYTDSQRPICLPSKGDRNV-IYTDCWVTGWGYRKLRDKIQNTLQKAK 536 Query: 180 VRVLDPDVCNSSWKGH-LTLTMLCTRSGDSHRRGFCSADSGGPLVCR----NRAHGLVSF 234 + ++ + C ++GH +T M+C + + C DSGGPL C+ G+ S+ Sbjct: 537 IPLVTNEECQKRYRGHKITHKMICAGYREGGK-DACKGDSGGPLSCKHNEVWHLVGITSW 595 Query: 235 SGLWCGDPKTPDVYTQVSAFVAWIWDVVRR 264 G C + P VYT V +V WI + + Sbjct: 596 -GEGCAQRERPGVYTNVVEYVDWILEKTQA 624 >1SGF-G nrPDB Length = 237 Score = 307 bits (786), Expect = 4e-84, Method: Composition-based stats. Identities = 71/244 (29%), Positives = 116/244 (47%), Gaps = 20/244 (8%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVL 93 I+GG + +S+P+ +V Q+ CGG LL WV++AAHC+ V LG + L Sbjct: 1 IVGGFKCEKNSQPWHVAVYRYTQYLCGGVLLDPNWVLTAAHCYDD----NYKVWLGKNNL 56 Query: 94 STAEPTQQVFGIDALTTHPDYHPM-----------THANDICLLRLNGSAVLGPAVGLLR 142 EP+ Q + HP ++ ++ND+ LLRL+ A + V + Sbjct: 57 FKDEPSAQHRFVSKAIPHPGFNMSLMRKHIRFLEYDYSNDLMLLRLSKPADITDTVKPIT 116 Query: 143 PPGRRARPPTAGTRCRVAGWGFVSDFE-ELPPGLMEAKVRVLDPDVCNSSWKGHLTLTML 201 P P G+ C +GWG ++ + + L +++L + C + +T ML Sbjct: 117 LP---TEEPKLGSTCLASGWGSITPTKFQFTDDLYCVNLKLLPNEDCAKAHIEKVTDAML 173 Query: 202 CTRSGDSHRRGFCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDV 261 C D + C DSGGPL+C G+ S+ CG+P P VYT+++ F +WI D Sbjct: 174 CAGEMDGGK-DTCKGDSGGPLICDGVLQGITSWGHTPCGEPDMPGVYTKLNKFTSWIKDT 232 Query: 262 VRRS 265 + ++ Sbjct: 233 MAKN 236 >1FXY-A nrPDB Length = 228 Score = 302 bits (774), Expect = 1e-82, Method: Composition-based stats. Identities = 66/235 (28%), Positives = 104/235 (44%), Gaps = 9/235 (3%) Query: 34 IIGGHEVTPHSRPYMASV-RFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHV 92 I+GG+ P+ A + + CGG +L ++++AAHC + V +G Sbjct: 1 IVGGYNCKDGEVPWQALLINEENEGFCGGTILSEFYILTAAHCLYQ--AKRFKVRVGDRN 58 Query: 93 LSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARPPT 152 E + V ++ + H + T+ DI +LRL V P PP Sbjct: 59 TEQEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPASLP---TAPPA 115 Query: 153 AGTRCRVAGWGFVSDFE-ELPPGLMEAKVRVLDPDVCNSSWKGHLTLTMLCTRSGDSHRR 211 GT+C ++GWG + + P L VL C +S+ G +T M C + + Sbjct: 116 TGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKITSNMFCVGFLEGGK- 174 Query: 212 GFCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVRRSS 266 C DSGGP+VC + G+VS+ G C P VYT+V +V WI + + +S Sbjct: 175 DSCQGDSGGPVVCNGQLQGVVSW-GDGCAQKNKPGVYTKVYNYVKWIKNTIAANS 228 >4NFE-A nrPDB Length = 237 Score = 301 bits (772), Expect = 2e-82, Method: Composition-based stats. Identities = 79/244 (32%), Positives = 114/244 (46%), Gaps = 20/244 (8%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVL 93 I+GG E HS+P+ +V G HCGG L+ +WV++AAHC + V LG H L Sbjct: 1 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLK----KNSQVWLGRHNL 56 Query: 94 STAEPTQQVFGIDALTTHPDYH-----------PMTHANDICLLRLNGSAVLGPAVGLLR 142 E T Q + HP Y+ ++D+ LLRL+ A + V +L Sbjct: 57 FEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLG 116 Query: 143 PPGRRARPPTAGTRCRVAGWGFVSDFEEL-PPGLMEAKVRVLDPDVCNSSWKGHLTLTML 201 P + P GT C +GWG + E L P L + +L D+C ++ +T ML Sbjct: 117 LPTQE---PALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFML 173 Query: 202 CTRSGDSHRRGFCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDV 261 C + + C DSGGPLVC G+ S+ C P+ P VYT+V + WI D Sbjct: 174 CAGLW-TGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDT 232 Query: 262 VRRS 265 + + Sbjct: 233 IAAN 236 >1SPJ-A nrPDB Length = 238 Score = 299 bits (765), Expect = 1e-81, Method: Composition-based stats. Identities = 73/246 (29%), Positives = 113/246 (45%), Gaps = 21/246 (8%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVL 93 I+GG E HS+P+ A++ CGG L+ +WV++AAHC S + LG H L Sbjct: 1 IVGGWECEQHSQPWQAALYHFSTFQCGGILVHRQWVLTAAHCISD----NYQLWLGRHNL 56 Query: 94 STAEPTQQVFGIDALTTHPDYH-----------PMTHANDICLLRLNGSA-VLGPAVGLL 141 E T Q + HP ++ +++D+ LLRL A + AV ++ Sbjct: 57 FDDENTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHDLMLLRLTEPADTITDAVKVV 116 Query: 142 RPPGRRARPPTAGTRCRVAGWGFVS-DFEELPPGLMEAKVRVLDPDVCNSSWKGHLTLTM 200 P P G+ C +GWG + + P L +++L D C + +T M Sbjct: 117 ELP---TEEPEVGSTCLASGWGSIEPENFSFPDDLQCVDLKILPNDECKKAHVQKVTDFM 173 Query: 201 LCTRSGDSHRRGFCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWD 260 LC + + C DSGGPL+C G+ S+ + CG P P V +V ++V WI D Sbjct: 174 LCVGHLEGGK-DTCVGDSGGPLMCDGVLQGVTSWGYVPCGTPNKPSVAVRVLSYVKWIED 232 Query: 261 VVRRSS 266 + +S Sbjct: 233 TIAENS 238 >2TLD-E nrPDB Length = 220 Score = 296 bits (759), Expect = 7e-81, Method: Composition-based stats. Identities = 77/233 (33%), Positives = 111/233 (47%), Gaps = 14/233 (6%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVL 93 I+GG+ ++ PY S+ G H CGG L+ ++WVVSAAHC+ V LG + Sbjct: 1 IVGGYTCGANTVPYQVSLN-SGYHFCGGSLINSQWVVSAAHCYKSG----IQVRLGEDNI 55 Query: 94 STAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARPPTA 153 + E +Q HP Y+ T NDI L++L +A L V + P A +A Sbjct: 56 NVVEGNEQFISASKSIVHPSYNSNTLNNDIMLIKLKSAASLNSRVASISLPTSCA---SA 112 Query: 154 GTRCRVAGWGFVSDFE-ELPPGLMEAKVRVLDPDVCNSSWKGHLTLTMLCTRSGDSHRRG 212 GT+C ++GWG P L K +L C S++ G +T M C Sbjct: 113 GTQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKSAYPGQITSNMFCAGLEGG---D 169 Query: 213 FCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVRRS 265 C DSGGP+VC + G+VS+ G C P VYT+V +V+WI + + Sbjct: 170 SCQGDSGGPVVCSGKLQGIVSW-GSGCA-KNKPGVYTKVCNYVSWIKQTIASN 220 >3QUM-P nrPDB Length = 237 Score = 294 bits (753), Expect = 3e-80, Method: Composition-based stats. Identities = 81/244 (33%), Positives = 116/244 (47%), Gaps = 20/244 (8%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVL 93 I+GG E HS+P+ V G+ CGG L+ +WV++AAHC ++ +++LG H L Sbjct: 1 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNK----SVILLGRHSL 56 Query: 94 STAEPTQQVFGIDALTTHPDYHP-----------MTHANDICLLRLNGSAVLGPAVGLLR 142 E T QVF + HP Y ++D+ LLRL+ A L AV ++ Sbjct: 57 FHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMD 116 Query: 143 PPGRRARPPTAGTRCRVAGWGFVSDFEEL-PPGLMEAKVRVLDPDVCNSSWKGHLTLTML 201 P + P GT C +GWG + E L P L + V+ DVC +T ML Sbjct: 117 LPTQE---PALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFML 173 Query: 202 CTRSGDSHRRGFCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDV 261 C + CS DSGGPLVC G+ S+ C P+ P +YT+V + WI D Sbjct: 174 CAGRWTGGK-STCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDT 232 Query: 262 VRRS 265 + + Sbjct: 233 IVAN 236 >1NPM-A nrPDB Length = 225 Score = 293 bits (750), Expect = 7e-80, Method: Composition-based stats. Identities = 80/233 (34%), Positives = 119/233 (51%), Gaps = 13/233 (5%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVL 93 I+ G E PHS+P+ A++ G + CGG L+ RWV++AAHC + V LG H L Sbjct: 1 ILEGRECIPHSQPWQAALFQGERLICGGVLVGDRWVLTAAHC----KKQKYSVRLGDHSL 56 Query: 94 STAEPTQQVFGIDALTTHPDYH---PMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARP 150 + + +Q + HP Y+ P H++DI L+RL SA LG V ++ Sbjct: 57 QSRDQPEQEIQVAQSIQHPCYNNSNPEDHSHDIMLIRLQNSANLGDKVKPVQLANL---C 113 Query: 151 PTAGTRCRVAGWGF-VSDFEELPPGLMEAKVRVLDPDVCNSSWKGHLTLTMLCTRSGDSH 209 P G +C ++GWG S E P L A+V++ + C ++ G +T M+C S S+ Sbjct: 114 PKVGQKCIISGWGTVTSPQENFPNTLNCAEVKIYSQNKCERAYPGKITEGMVCAGS--SN 171 Query: 210 RRGFCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVV 262 C DSGGPLVC G+ S+ CG P+ P VYT++ + WI + Sbjct: 172 GADTCQGDSGGPLVCDGMLQGITSWGSDPCGKPEKPGVYTKICRYTTWIKKTM 224 >5MS3-A nrPDB Length = 228 Score = 291 bits (746), Expect = 2e-79, Method: Composition-based stats. Identities = 78/236 (33%), Positives = 113/236 (47%), Gaps = 13/236 (5%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVL 93 ++GGHE PHS+P+ A++ G Q CGG L+ WV++AAHC + V LG H L Sbjct: 1 VLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHCKKPK----YTVRLGDHSL 56 Query: 94 STAEPTQQVFGIDALTTHPDYHP---MTHANDICLLRLNGSAVLGPAVGLLRPPGRRARP 150 + +Q + HP Y+ H +D+ LL+L A LG V + +P Sbjct: 57 QNKDGPEQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQASLGSKVKPISLADHCTQP 116 Query: 151 PTAGTRCRVAGWGF-VSDFEELPPGLMEAKVRVLDPDVCNSSWKGHLTLTMLCTRSGDSH 209 G +C V+GWG S E P L A+V++ C ++ G +T M+C S S Sbjct: 117 ---GQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQITDGMVCAGS--SK 171 Query: 210 RRGFCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVRRS 265 C DSGGPLVC G+ S+ CG P VYT + ++ WI ++ Sbjct: 172 GADTCQGDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWIKKIIGSK 227 >6I44-A nrPDB Length = 627 Score = 290 bits (742), Expect = 6e-79, Method: Composition-based stats. Identities = 67/274 (24%), Positives = 116/274 (42%), Gaps = 21/274 (7%) Query: 4 GLRGWGRPLLTV--ATALMLPVKPPAGSWGAQIIGGHEVTPHSRPYMASVRFG---GQHH 58 G G+ L + +I+GG + + P+ S++ +H Sbjct: 355 GSSGYSLRLCNTGDNSVCTTK-------TSTRIVGGTQSSWGEWPWQVSLQVKLTAQRHL 407 Query: 59 CGGFLLRARWVVSAAHCFSHRDLRT-GLVVLGAHVLSTAEPTQQVFGIDALTTHPDYHPM 117 CGG L+ +WV++AAHCF L+ + G LS I + H +Y Sbjct: 408 CGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSGILQLSDITKDTPFSQIKEIIIHQNYKVS 467 Query: 118 THANDICLLRLNGSAVLGPAVGLLRPPGRRARPPTAGTRCRVAGWGFVSDFEELPPGLME 177 +DI L++L + P + T T C V GWGF ++ E+ L + Sbjct: 468 EGNHDIALIKLQAPLQYTEFQKPICLPSKG-DTSTIYTNCWVTGWGFSAEAGEIQNILQK 526 Query: 178 AKVRVLDPDVCNSSWKGH-LTLTMLCTRSGDSHRRGFCSADSGGPLVCR----NRAHGLV 232 + ++ + C ++ + +T M+C + + C D+GGPLVC+ R G+ Sbjct: 527 VNIPLVTNEECQKRYQDYKITQRMVCAGYKEGGK-DACKGDAGGPLVCKHNGMWRLVGIT 585 Query: 233 SFSGLWCGDPKTPDVYTQVSAFVAWIWDVVRRSS 266 S+ G C + P VYT+V+ ++ WI + + S Sbjct: 586 SW-GEGCARREQPGVYTKVAEYMDWILEKTQSSD 618 >2EEK-A nrPDB Length = 220 Score = 289 bits (740), Expect = 1e-78, Method: Composition-based stats. Identities = 75/230 (32%), Positives = 106/230 (46%), Gaps = 10/230 (4%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVL 93 I+GG+E T HS+ + S+ G H CGG L+ WVVSAAHC+ V LG H + Sbjct: 1 IVGGYECTKHSQAHQVSLN-SGYHFCGGSLVSKDWVVSAAHCYKS----VLRVRLGEHHI 55 Query: 94 STAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARPPTA 153 E T+Q ++ HP+Y NDI L++L A L V + P A Sbjct: 56 RVNEGTEQYISSSSVIRHPNYSSYNINNDIMLIKLTKPATLNQYVHAVALPTECAADA-- 113 Query: 154 GTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWKGHLTLTMLCTRSGDSHRRGF 213 T C V+GWG L + +L C +S+ G +T +M C + + Sbjct: 114 -TMCTVSGWGNTMSSVADGDKLQCLSLPILSHADCANSYPGMITQSMFCAGYLEGGK-DS 171 Query: 214 CSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVR 263 C DSGGP+VC G+VS+ G C + P VY +V W+ D + Sbjct: 172 CQGDSGGPVVCNGVLQGVVSW-GYGCAERDHPGVYAKVCVLSGWVRDTMA 220 >5TJX-A nrPDB Length = 263 Score = 286 bits (733), Expect = 5e-78, Method: Composition-based stats. Identities = 66/246 (26%), Positives = 110/246 (44%), Gaps = 12/246 (4%) Query: 30 WGAQIIGGHEVTPHSRPYMASVRFG---GQHHCGGFLLRARWVVSAAHCFSHRDLRT-GL 85 +I+GG E + P+ S++ +H CGG L+ +WV++AAHCF L+ Sbjct: 12 TSTRIVGGTESSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWR 71 Query: 86 VVLGAHVLSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPG 145 + G LS I + H +Y +DI L++L + P Sbjct: 72 IYSGILELSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLEYTEFQKPISLPS 131 Query: 146 RRARPPTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWKGH-LTLTMLCTR 204 + T T C V GWGF + E+ L + + ++ + C ++ + +T M+C Sbjct: 132 KG-DTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAG 190 Query: 205 SGDSHRRGFCSADSGGPLVCR----NRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWD 260 + + C DSGGPLVC+ R G+ S+ G C + P VYT+V+ ++ WI + Sbjct: 191 YKEGGK-DACKGDSGGPLVCKHNGMWRLVGITSW-GEGCARREQPGVYTKVAEYMDWILE 248 Query: 261 VVRRSS 266 + S Sbjct: 249 KTQSSD 254 >3E0N-B nrPDB Length = 271 Score = 286 bits (733), Expect = 7e-78, Method: Composition-based stats. Identities = 79/260 (30%), Positives = 113/260 (43%), Gaps = 18/260 (6%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCF-SHRDLRTGLVVLGAHV 92 I GG P+ S+ + G H CGG L+ +WV+SAAHCF S V LGAH Sbjct: 1 ITGGSSAVAGQWPWQVSITYEGVHVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKLGAHQ 60 Query: 93 LSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARPPT 152 L + +V + + HP Y DI LL+L+ + + P +A P Sbjct: 61 LDSYSEDAKVSTLKDIIPHPSYLQEGSQGDIALLQLSRPITFSRYIRPISLPAAQASFPN 120 Query: 153 AGTRCRVAGWGFVSDFEEL--PPGLMEAKVRVLDPDVCNSSW--------KGHLTLTMLC 202 G C V GWG V+ L P L + +V ++ + CNS + + M+C Sbjct: 121 -GLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNSLYNIDAKPEEPHFVQEDMVC 179 Query: 203 TRSGDSHRRGFCSADSGGPLVCR----NRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWI 258 + + C DSGGPL C G+VS+ G CG P VYT S++ +WI Sbjct: 180 AGYVEGGK-DACQGDSGGPLSCPVEGLWYLTGIVSW-GDACGARNRPGVYTLASSYASWI 237 Query: 259 WDVVRRSSPQPGPLPGTTRP 278 V P+ P ++P Sbjct: 238 QSKVTELQPRVVPQTQESQP 257 >1EUF-A nrPDB Length = 227 Score = 286 bits (732), Expect = 7e-78, Method: Composition-based stats. Identities = 95/234 (40%), Positives = 124/234 (52%), Gaps = 12/234 (5%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQ---HHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGA 90 IIGGHE PHSRPYMA + F H CGGFL+R +V++AAHC + V LGA Sbjct: 1 IIGGHEAKPHSRPYMAFLLFKTSGKSHICGGFLVREDFVLTAAHCLGS----SINVTLGA 56 Query: 91 HVLSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARP 150 H + E TQQV + HPDY+ T ANDI LL+L A + V + P R Sbjct: 57 HNIMERERTQQVIPVRRPIPHPDYNDETLANDIMLLKLTRKADITDKVSPINLP-RSLAE 115 Query: 151 PTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWKGHLTLTMLCTRSGDSHR 210 G C VAGWG + L E + V + C + +K ++ T +C S R Sbjct: 116 VKPGMMCSVAGWGRLGVNMPSTDKLQEVDLEVQSEEKCIARFKNYIPFTQICAGDP-SKR 174 Query: 211 RGFCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVRR 264 + S DSGGPLVC A G+VS+ D TPDVYT++S+F++WI +RR Sbjct: 175 KNSFSGDSGGPLVCNGVAQGIVSYGR---NDGTTPDVYTRISSFLSWIHSTMRR 225 >3T2N-A nrPDB Length = 372 Score = 285 bits (729), Expect = 2e-77, Method: Composition-based stats. Identities = 76/259 (29%), Positives = 115/259 (44%), Gaps = 19/259 (7%) Query: 32 AQIIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAH 91 +I+GG + + P+ S+R+ G H CGG LL WV++AAHCF R+ + A Sbjct: 116 DRIVGGRDTSLGRWPWQVSLRYDGAHLCGGSLLSGDWVLTAAHCFPERNRVLSRWRVFAG 175 Query: 92 VLSTAEPTQQVFGIDALTTHPDY------HPMTHANDICLLRLNGSAVLGPAVGLLRPPG 145 ++ A P G+ A+ H Y + ++NDI L+ L+ L + + P Sbjct: 176 AVAQASPHGLQLGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLTEYIQPVCLPA 235 Query: 146 RRARPPTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCN--SSWKGHLTLTMLCT 203 G C V GWG + + L EA+V ++ DVCN + + M C Sbjct: 236 AGQALVD-GKICTVTGWGNTQYYGQQAGVLQEARVPIISNDVCNGADFYGNQIKPKMFCA 294 Query: 204 RSGDSHRRGFCSADSGGPLVCRN--------RAHGLVSFSGLWCGDPKTPDVYTQVSAFV 255 + C DSGGP VC + R G+VS+ G C + P VYT+VS F Sbjct: 295 GYPEGGI-DACQGDSGGPFVCEDSISRTPRWRLCGIVSW-GTGCALAQKPGVYTKVSDFR 352 Query: 256 AWIWDVVRRSSPQPGPLPG 274 WI+ ++ S G + Sbjct: 353 EWIFQAIKTHSEASGMVTQ 371 >1AO5-A nrPDB Length = 237 Score = 284 bits (726), Expect = 4e-77, Method: Composition-based stats. Identities = 68/245 (27%), Positives = 114/245 (46%), Gaps = 20/245 (8%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVL 93 ++GG +S+P+ +V + +H CGG LL WV++AAHC+ + V LG + L Sbjct: 1 VVGGFNCEKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQ----YEVWLGKNKL 56 Query: 94 STAEPTQQVFGIDALTTHPDYHP-----------MTHANDICLLRLNGSAVLGPAVGLLR 142 EP+ Q + HP ++ ++D+ LLRL+ A + V + Sbjct: 57 FQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSDDLMLLRLSKPADITDVVKPIA 116 Query: 143 PPGRRARPPTAGTRCRVAGWGFVSDFE-ELPPGLMEAKVRVLDPDVCNSSWKGHLTLTML 201 P + P G++C +GWG ++ + P L + +L + C + +T ML Sbjct: 117 LPTKE---PKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDVML 173 Query: 202 CTRSGDSHRRGFCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDV 261 C + C DSGGPL+C G S+ + CG P P +YT + F +WI D Sbjct: 174 CAGEM-GGGKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDT 232 Query: 262 VRRSS 266 + +++ Sbjct: 233 MMKNA 237 >1TON-A nrPDB Length = 235 Score = 283 bits (724), Expect = 7e-77, Method: Composition-based stats. Identities = 73/244 (29%), Positives = 120/244 (49%), Gaps = 22/244 (9%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVL 93 I+GG++ +S+P+ +V ++ CGG L+ WV++AAHC+S V+LG + L Sbjct: 1 IVGGYKCEKNSQPWQVAV--INEYLCGGVLIDPSWVITAAHCYS----NNYQVLLGRNNL 54 Query: 94 STAEPTQQVFGIDALTTHPDYHPM-----------THANDICLLRLNGSAVLGPAVGLLR 142 EP Q + HPDY P+ H+ND+ LL L+ A + V ++ Sbjct: 55 FKDEPFAQRRLVRQSFRHPDYIPLIVTNDTEQPVHDHSNDLMLLHLSEPADITGGVKVID 114 Query: 143 PPGRRARPPTAGTRCRVAGWGFVSDFE-ELPPGLMEAKVRVLDPDVCNSSWKGHLTLTML 201 P + P G+ C +GWG + E + L + +L + C ++K ++T ML Sbjct: 115 LPTKE---PKVGSTCLASGWGSTNPSEMVVSHDLQCVNIHLLSNEKCIETYKDNVTDVML 171 Query: 202 CTRSGDSHRRGFCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDV 261 C + + C+ DSGGPL+C G+ S C PKTP +Y ++ F +WI V Sbjct: 172 CAGEMEGGK-DTCAGDSGGPLICDGVLQGITSGGATPCAKPKTPAIYAKLIKFTSWIKKV 230 Query: 262 VRRS 265 ++ + Sbjct: 231 MKEN 234 >1FI8-A nrPDB Length = 228 Score = 283 bits (724), Expect = 7e-77, Method: Composition-based stats. Identities = 87/237 (36%), Positives = 121/237 (51%), Gaps = 14/237 (5%) Query: 34 IIGGHEVTPHSRPYMASVR----FGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLG 89 IIGGHE PHSRPYMA ++ + G CGGFL+R +V++AAHC + V LG Sbjct: 1 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSK----IQVTLG 56 Query: 90 AHVLSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRAR 149 AH + E QQ+ + + HP Y+ T +NDI LL+L A AV L P R + Sbjct: 57 AHNIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVK 116 Query: 150 PPTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWKGHL-TLTMLCTRSGDS 208 G C VAGWG + + L E ++ V + C S K + +C Sbjct: 117 -VKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDP-K 174 Query: 209 HRRGFCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVRRS 265 +R DSGGPLVC+ A G+VS+ D TP +T+VS F++WI +++S Sbjct: 175 IKRASFRGDSGGPLVCKKVAAGIVSYGQ---NDGSTPRAFTKVSTFLSWIKKTMKKS 228 >5GVT-A nrPDB Length = 250 Score = 281 bits (720), Expect = 2e-76, Method: Composition-based stats. Identities = 64/242 (26%), Positives = 102/242 (42%), Gaps = 12/242 (4%) Query: 34 IIGGHEVTPHSRPYMASVRF---GGQHHCGGFLLRARWVVSAAHCFSHRD-LRTGLVVLG 89 I+GG + P+ S++ H CGG ++ +WV++AAHCF + G Sbjct: 1 IVGGTNASLGEWPWQVSLQVKLVSQTHLCGGSIIGRQWVLTAAHCFDGIPYPDVWRIYGG 60 Query: 90 AHVLSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRAR 149 LS I L H +Y DI L++L + P + A Sbjct: 61 ILSLSEITKETPSSRIKELIIHQEYKVSEGNYDIALIKLQTPLNYTEFQKPISLPSK-AD 119 Query: 150 PPTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWKGHLTL-TMLCTRSGDS 208 T T C V GWG+ + E L +A + ++ + C ++ ++ M+C + Sbjct: 120 TNTIYTNCWVTGWGYTKEQGETQNILQKATIPLVPNEECQKKYRDYVINKQMICAGYKEG 179 Query: 209 HRRGFCSADSGGPLVCR----NRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVRR 264 C DSGGPLVC+ + G+ S+ G C P VYT+VS ++ WI + + Sbjct: 180 G-TDACKGDSGGPLVCKHSGRWQLVGITSW-GEGCARKDQPGVYTKVSEYMDWILEKTQS 237 Query: 265 SS 266 S Sbjct: 238 SD 239 >3BSQ-A nrPDB Length = 227 Score = 281 bits (720), Expect = 2e-76, Method: Composition-based stats. Identities = 87/231 (37%), Positives = 114/231 (49%), Gaps = 11/231 (4%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVL 93 II G S P+ ++ G Q HCGG L+ RWV++AAHC + V LG+ L Sbjct: 1 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHC----KMNEYTVHLGSDTL 56 Query: 94 STAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARPPTA 153 + Q HP Y TH ND+ L++LN A L V +R P R Sbjct: 57 G--DRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSR---CEPP 111 Query: 154 GTRCRVAGWGFVSDFE-ELPPGLMEAKVRVLDPDVCNSSWKGHLTLTMLCTRSGDSHRRG 212 GT C V+GWG + + P LM V+++ P C +K L +MLC DS ++ Sbjct: 112 GTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDS-KKN 170 Query: 213 FCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVR 263 C+ DSGGPLVCR GLVS+ CG P P VYTQV F WI D ++ Sbjct: 171 ACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMK 221 >1FDP-A nrPDB Length = 235 Score = 281 bits (720), Expect = 2e-76, Method: Composition-based stats. Identities = 98/239 (41%), Positives = 132/239 (55%), Gaps = 6/239 (2%) Query: 27 AGSWGAQIIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLV 86 A +I+GG E H+RPYMASV+ G H CGG L+ +WV+SAAHC V Sbjct: 1 AAPPRGRILGGREAEAHARPYMASVQLNGAHLCGGVLVAEQWVLSAAHCLEDAADGKVQV 60 Query: 87 VLGAHVLSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGR 146 +LGAH LS EP+++++ + HPD P T +D+ LL+L+ A LGPAV L P R Sbjct: 61 LLGAHSLSQPEPSKRLYDVLRAVPHPDSQPDTIDHDLLLLQLSEKATLGPAVRPL-PWQR 119 Query: 147 RARPPTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNS--SWKGHLTLTMLCTR 204 R GT C VAGWG V+ P L + VLD CN G +T ++C Sbjct: 120 VDRDVAPGTLCDVAGWGIVNHAGRRPDSLQHVLLPVLDRATCNRRTHHDGAITERLMCA- 178 Query: 205 SGDSHRRGFCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVR 263 +S+RR C DSGGPLVC G+V+ CG+ K P +YT+V+++ AWI V+ Sbjct: 179 --ESNRRDSCKGDSGGPLVCGGVLEGVVTSGSRVCGNRKKPGIYTRVASYAAWIDSVLA 235 >1SGF-A nrPDB Length = 240 Score = 280 bits (718), Expect = 4e-76, Method: Composition-based stats. Identities = 69/252 (27%), Positives = 117/252 (46%), Gaps = 25/252 (9%) Query: 26 PAGSWGAQIIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGL 85 A +Q+ + +S+P+ +V ++ CGG LL WV++AAHC++ + Sbjct: 1 AAPPVQSQV----DCE-NSQPWHVAVYRFNKYQCGGVLLDRNWVLTAAHCYNDK----YQ 51 Query: 86 VVLGAHVLSTAEPTQQVFGIDALTTHPDYHP-----------MTHANDICLLRLNGSAVL 134 V LG + EP+ Q + HPD++ ++ND+ LLRL+ A + Sbjct: 52 VWLGKNNFLEDEPSDQHRLVSKAIPHPDFNMSLLNEHTPQPEDDYSNDLMLLRLSKPADI 111 Query: 135 GPAVGLLRPPGRRARPPTAGTRCRVAGWGFVSDFE-ELPPGLMEAKVRVLDPDVCNSSWK 193 V + P P G+ C +GWG + + + P L +++L + C+ + + Sbjct: 112 TDVVKPITLP---TEEPKLGSTCLASGWGSTTPIKFKYPDDLQCVNLKLLPNEDCDKAHE 168 Query: 194 GHLTLTMLCTRSGDSHRRGFCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSA 253 +T MLC D C DSGGPL+C G+ S+ CG+P P VYT++ Sbjct: 169 MKVTDAMLCAGEMDGG-SYTCEHDSGGPLICDGILQGITSWGPEPCGEPTEPSVYTKLIK 227 Query: 254 FVAWIWDVVRRS 265 F +WI + + + Sbjct: 228 FSSWIRETMANN 239 >4GSO-A nrPDB Length = 232 Score = 280 bits (717), Expect = 4e-76, Method: Composition-based stats. Identities = 66/240 (27%), Positives = 105/240 (43%), Gaps = 11/240 (4%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVL 93 ++GG E + P++A + G + CG L+ WVV+AAHC D + LG H Sbjct: 1 VLGGDECDINEHPFLAFLYSHG-YFCGLTLINQEWVVTAAHC----DSTNFQMQLGVHSK 55 Query: 94 STAEPTQQVFGIDALTTHPDYHPMT-HANDICLLRLNGSAVLGPAVGLLRPPGRRARPPT 152 +Q P+ + DI L++L+ + L P PP+ Sbjct: 56 KVLNEDEQTRNPKEKFICPNKNMSEVLDKDIMLIKLDKPISNSKHIAPLSLPS---NPPS 112 Query: 153 AGTRCRVAGWGFVS-DFEELPPGLMEAKVRVLDPDVCNSSWKGHLTLTMLCTRSGDSHRR 211 G+ CR+ GWG ++ E P A + ++D +VC ++ G T LC + + Sbjct: 113 VGSVCRIMGWGSITIPNETYPDVPYCANINLVDYEVCQGAYNGLPAKTTLCAGVLEGGK- 171 Query: 212 GFCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVRRSSPQPGP 271 C DSGGPL+C + G+VS+ CG P +YT V + WI + ++ P Sbjct: 172 DTCVGDSGGPLICNGQFQGIVSYGAHSCGQGPKPGIYTNVFDYTDWIQRNIAGNTDATCP 231 >2PSX-A nrPDB Length = 227 Score = 279 bits (715), Expect = 8e-76, Method: Composition-based stats. Identities = 75/236 (31%), Positives = 111/236 (47%), Gaps = 12/236 (5%) Query: 34 IIGGHEVTPHSRPYMASVRFG-GQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHV 92 II G + H++P+ A++ Q +CG L+ +W+++AAHC + V LG + Sbjct: 1 IINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHC----RKKVFRVRLGHYS 56 Query: 93 LS-TAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARPP 151 LS E QQ+F HP Y H+ND+ L++LN V + + P Sbjct: 57 LSPVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPI---NVSSHCP 113 Query: 152 TAGTRCRVAGWGFVSDFE-ELPPGLMEAKVRVLDPDVCNSSWKGHLTLTMLCTRSGDSHR 210 +AGT+C V+GWG + P L + VL C ++ + TM C D Sbjct: 114 SAGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAG--DKAG 171 Query: 211 RGFCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVRRSS 266 R C DSGGP+VC GLVS+ C P P VYT + F WI + ++ +S Sbjct: 172 RDSCQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQANS 227 >1P57-B nrPDB Length = 255 Score = 278 bits (712), Expect = 2e-75, Method: Composition-based stats. Identities = 76/257 (29%), Positives = 114/257 (44%), Gaps = 19/257 (7%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVL 93 I+GG + + P+ S+R+ G H CGG LL WV++AAHCF R+ + A + Sbjct: 1 IVGGRDTSLGRWPWQVSLRYDGAHLCGGSLLSGDWVLTAAHCFPERNRVLSRWRVFAGAV 60 Query: 94 STAEPTQQVFGIDALTTHPDY------HPMTHANDICLLRLNGSAVLGPAVGLLRPPGRR 147 + A P G+ A+ H Y + ++NDI L+ L+ L + + P Sbjct: 61 AQASPHGLQLGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLTEYIQPVCLPAAG 120 Query: 148 ARPPTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCN--SSWKGHLTLTMLCTRS 205 G C V GWG + + L EA+V ++ DVCN + + M C Sbjct: 121 QALVD-GKICTVTGWGNTQYYGQQAGVLQEARVPIISNDVCNGADFYGNQIKPKMFCAGY 179 Query: 206 GDSHRRGFCSADSGGPLVCRN--------RAHGLVSFSGLWCGDPKTPDVYTQVSAFVAW 257 + C DSGGP VC + R G+VS+ G C + P VYT+VS F W Sbjct: 180 PEGGI-DACQGDSGGPFVCEDSISRTPRWRLCGIVSW-GTGCALAQKPGVYTKVSDFREW 237 Query: 258 IWDVVRRSSPQPGPLPG 274 I+ ++ S G + Sbjct: 238 IFQAIKTHSEASGMVTQ 254 >1GVZ-A nrPDB Length = 237 Score = 278 bits (712), Expect = 2e-75, Method: Composition-based stats. Identities = 71/245 (28%), Positives = 107/245 (43%), Gaps = 20/245 (8%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVL 93 IIGG E HS+P+ +V G CGG L+ +WV++AAHC S + LG H L Sbjct: 1 IIGGWECEKHSKPWQVAVYHQGHFQCGGVLVHPQWVLTAAHCMSD----DYQIWLGRHNL 56 Query: 94 STAEPTQQVFGIDALTTHPDYH-----------PMTHANDICLLRLNGSAVLGPAVGLLR 142 S E T Q + P + ++D+ LLRL A + AV +L Sbjct: 57 SKDEDTAQFHQVSDSFLDPQFDLSLLKKKYLRPYDDISHDLMLLRLAQPARITDAVKILD 116 Query: 143 PPGRRARPPTAGTRCRVAGWGFVSD-FEELPPGLMEAKVRVLDPDVCNSSWKGHLTLTML 201 P + P G+ C +GWG +S L ++R+ + C ++ +T +L Sbjct: 117 LPTQE---PKLGSTCYTSGWGLISTFTNRGSGTLQCVELRLQSNEKCARAYPEKMTEFVL 173 Query: 202 CTRSGDSHRRGFCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDV 261 C D C DSGG L+C G+ S+ C D V+T+V WI + Sbjct: 174 CATHRDDSG-SICLGDSGGALICDGVFQGITSWGYSECADFNDNFVFTKVMPHKKWIKET 232 Query: 262 VRRSS 266 + ++S Sbjct: 233 IEKNS 237 >1BRU-P nrPDB Length = 241 Score = 277 bits (708), Expect = 5e-75, Method: Composition-based stats. Identities = 78/246 (31%), Positives = 113/246 (45%), Gaps = 19/246 (7%) Query: 34 IIGGHEVTPHSRPYMASVRFGG----QHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLG 89 ++GG + P+S P+ S+++ +H CGG L+ WV++AAHC S RT VVLG Sbjct: 1 VVGGEDARPNSWPWQVSLQYDSSGQWRHTCGGTLVDQSWVLTAAHCISSS--RTYRVVLG 58 Query: 90 AHVLSTAEPTQQVFGIDALTTHPDYHPMTH--ANDICLLRLNGSAVLGPAVGLLRPPGRR 147 H LST EP + L H D++ NDI LL+L L + L P Sbjct: 59 RHSLSTNEPGSLAVKVSKLVVHQDWNSNQLSNGNDIALLKLASPVSLTDKIQLGCLPAAG 118 Query: 148 ARPPTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNS--SWKGHLTLTMLCTRS 205 P C V GWG + P L + ++ V+D C+ W + M+C Sbjct: 119 TILPN-NYVCYVTGWGRLQTNGASPDILQQGQLLVVDYATCSKPGWWGSTVKTNMICAGG 177 Query: 206 GDSHRRGFCSADSGGPLVCRN-----RAHGLVSFSGL-WCGDPKTPDVYTQVSAFVAWIW 259 C+ DSGGPL C+ + HG+VSF C P V+T+VS ++ WI Sbjct: 178 --DGIISSCNGDSGGPLNCQGANGQWQVHGIVSFGSSLGCNYYHKPSVFTRVSNYIDWIN 235 Query: 260 DVVRRS 265 V+ + Sbjct: 236 SVIANN 241 >3W94-A nrPDB Length = 235 Score = 277 bits (708), Expect = 5e-75, Method: Composition-based stats. Identities = 76/238 (31%), Positives = 117/238 (49%), Gaps = 11/238 (4%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRD--LRTGLVVLGAH 91 ++GG + P+M S+ + G+H CG L+ W+++AAHC ++ L+ VLG H Sbjct: 1 VVGGVNAEKGAWPWMVSLHWRGRHGCGASLIGRDWLLTAAHCVYGKNTHLQYWSAVLGLH 60 Query: 92 VLSTAEPTQ-QVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARP 150 S+ + Q+ +D + + +Y+ T DI ++ L V + Sbjct: 61 AQSSMNSQEVQIRQVDRIIINKNYNRRTKEADIAMMHLQQPVNFTEWVLPVCLASEDQHF 120 Query: 151 PTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWKGH-LTLTMLCTRSGDSH 209 P AG RC +AGWG ++ LP L EA+V ++D D C + T +MLC + Sbjct: 121 P-AGRRCFIAGWGRDAEGGSLPDILQEAEVPLVDQDECQRLLPEYTFTSSMLCAGYPEGG 179 Query: 210 RRGFCSADSGGPLVC----RNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVR 263 C DSGGPL+C R G+ SF G+ CG P+ P Y +VSAF +WI + R Sbjct: 180 -VDSCQGDSGGPLMCLEDARWTLIGVTSF-GVGCGRPERPGAYARVSAFTSWIAETRR 235 >5ZFH-A nrPDB Length = 224 Score = 276 bits (707), Expect = 6e-75, Method: Composition-based stats. Identities = 78/233 (33%), Positives = 111/233 (47%), Gaps = 11/233 (4%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVL 93 II G++ S P+ ++ G Q HCGG L+ WV++AAHC + V LG Sbjct: 1 IIDGYKCKEGSHPWQVALLKGNQLHCGGVLVDKYWVLTAAHCKMGQ----YQVQLG--SD 54 Query: 94 STAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARPPTA 153 + + Q HP Y TH NDI L+RL+ + V ++ P Sbjct: 55 KIGDQSAQKIKATKSFRHPGYSTKTHVNDIMLVRLDEPVKMSSKVEAVQLPE---HCEPP 111 Query: 154 GTRCRVAGWGFVSDFE-ELPPGLMEAKVRVLDPDVCNSSWKGHLTLTMLCTRSGDSHRRG 212 GT C V+GWG + + P LM + V+++ C +K L TMLC DS + Sbjct: 112 GTSCTVSGWGTTTSPDVTFPSDLMCSDVKLISSRECKKVYKDLLGKTMLCAGIPDS-KTN 170 Query: 213 FCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVRRS 265 C+ DSGGPLVC + GLVS+ CG P P VYTQV + W+ + ++ Sbjct: 171 TCNGDSGGPLVCNDTLQGLVSWGTYPCGQPNDPGVYTQVCKYKRWVMETMKTH 223 >1X7A-C nrPDB Length = 235 Score = 276 bits (707), Expect = 7e-75, Method: Composition-based stats. Identities = 63/237 (26%), Positives = 95/237 (40%), Gaps = 11/237 (4%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVL 93 I+GG P P+ + CGG ++ +WVV+AAHC VV G + Sbjct: 1 IVGGENAKPGQFPWQVLLNGKIDAFCGGSIINEKWVVTAAHCIE--PGVKITVVAGEYNT 58 Query: 94 STAEPTQQVFGIDALTTHPDYHP--MTHANDICLLRLNGSAVLGPAVGLLRPPGRRARPP 151 EPT+Q + H Y+ +++DI LL L+ L V + + Sbjct: 59 EETEPTEQRRNVIRAIPHHSYNATVNKYSHDIALLELDEPLTLNSYVTPICIADKEYTNI 118 Query: 152 TAGT-RCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWKGHLTLTMLCTRSGDSHR 210 V+GWG V + L KV ++D C S K + M C + + Sbjct: 119 FLKFGSGYVSGWGRVFNRGRSATILQYLKVPLVDRATCLRSTKFTIYSNMFCAGFHEGGK 178 Query: 211 RGFCSADSGGPLVCRNR----AHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVR 263 C DSGGP V G++S+ G C +YT+VS +V WI + + Sbjct: 179 -DSCQGDSGGPHVTEVEGTSFLTGIISW-GEECAVKGKYGIYTKVSRYVNWIKEKTK 233 >1KIG-H nrPDB Length = 241 Score = 276 bits (706), Expect = 7e-75, Method: Composition-based stats. Identities = 63/244 (25%), Positives = 97/244 (39%), Gaps = 11/244 (4%) Query: 34 IIGGHEVTPHSRPYMASV-RFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHV 92 I+GG + P+ A + + CGG +L +V++AAHC + V +G Sbjct: 1 IVGGRDCAEGECPWQALLVNEENEGFCGGTILNEFYVLTAAHCLHQ--AKRFTVRVGDRN 58 Query: 93 LSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARPPT 152 E + ++ H + T+ DI +LRL V P + T Sbjct: 59 TEQEEGNEMAHEVEMTVKHSRFVKETYDFDIAVLRLKTPIRFRRNVAPACLPEKDWAEAT 118 Query: 153 AGTR--CRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWKGHLTLTMLCTRSGDSHR 210 T+ V+G+G + L L +V +D C S +T M C D+ Sbjct: 119 LMTQKTGIVSGFGRTHEKGRLSSTLKMLEVPYVDRSTCKLSSSFTITPNMFCAGY-DTQP 177 Query: 211 RGFCSADSGGPLVCR----NRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVRRSS 266 C DSGGP V R G+VS+ G C VYT+VS F+ WI +++ + Sbjct: 178 EDACQGDSGGPHVTRFKDTYFVTGIVSW-GEGCARKGKFGVYTKVSNFLKWIDKIMKARA 236 Query: 267 PQPG 270 G Sbjct: 237 GAAG 240 >6AOD-C nrPDB Length = 245 Score = 275 bits (704), Expect = 1e-74, Method: Composition-based stats. Identities = 62/240 (25%), Positives = 105/240 (43%), Gaps = 12/240 (5%) Query: 34 IIGGHEVTPHSRPYMASVRFGG---QHHCGGFLLRARWVVSAAHCFSH-RDLRTGLVVLG 89 I+GG P+ ++ +H CGG ++ +W+++AAHCF + V G Sbjct: 1 IVGGTASVRGEWPWQVTLHTTSPTQRHLCGGSIIGNQWILTAAHCFYGVESPKILRVYSG 60 Query: 90 AHVLSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRAR 149 S + FG+ + H Y DI LL+L + + + P + R Sbjct: 61 ILQQSEIKEDTSFFGVQEIIIHDQYKMAESGYDIALLKLETTVQYTDSQRPISLPSKGDR 120 Query: 150 PPTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWKGH-LTLTMLCTRSGDS 208 T C V GWG+ +++ L +AK+ ++ + C ++GH +T M+C + Sbjct: 121 NV-IYTDCWVTGWGYRKLRDKIQNTLQKAKIPLVTNEECQKRYRGHKITHKMICAGYREG 179 Query: 209 HRRGFCSADSGGPLVCR----NRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVRR 264 + C D+GGPL C+ G+ S+ G C + P VYT V +V WI + + Sbjct: 180 GK-DACKGDAGGPLSCKHNEVWHLVGITSW-GEGCAQRERPGVYTNVVEYVDWILEKTQA 237 >2CGA-A nrPDB Length = 245 Score = 274 bits (701), Expect = 3e-74, Method: Composition-based stats. Identities = 75/253 (29%), Positives = 111/253 (43%), Gaps = 14/253 (5%) Query: 19 LMLPVKPPAGSWGAQIIGGHEVTPHSRPYMASVRF-GGQHHCGGFLLRARWVVSAAHCFS 77 +P P S ++I+ G E P S P+ S++ G H CGG L+ WVV+AAHC Sbjct: 1 CGVPAIQPVLSGLSRIVNGEEAVPGSWPWQVSLQDKTGFHFCGGSLINENWVVTAAHC-- 58 Query: 78 HRDLRTGLVVLGAHVLSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPA 137 + +VV G ++ Q I + + Y+ +T NDI LL+L+ +A Sbjct: 59 -GVTTSDVVVAGEFDQGSSSEKIQKLKIAKVFKNSKYNSLTINNDITLLKLSTAASFSQT 117 Query: 138 VGLLRPPGRRARPPTAGTRCRVAGWGFVS-DFEELPPGLMEAKVRVLDPDVCNSSWKGHL 196 V + P + AGT C GWG P L +A + +L C W + Sbjct: 118 VSAVCLPS-ASDDFAAGTTCVTTGWGLTRYTNANTPDRLQQASLPLLSNTNCKKYWGTKI 176 Query: 197 TLTMLCTRSGDSHRRGFCSADSGGPLVCR----NRAHGLVSFSGLWCGDPKTPDVYTQVS 252 M+C + C DSGGPLVC+ G+VS+ C TP VY +V+ Sbjct: 177 KDAMICAGAS---GVSSCMGDSGGPLVCKKNGAWTLVGIVSWGSSTCSTS-TPGVYARVT 232 Query: 253 AFVAWIWDVVRRS 265 A V W+ + + Sbjct: 233 ALVNWVQQTLAAN 245 >5FCR-A nrPDB Length = 234 Score = 274 bits (701), Expect = 3e-74, Method: Composition-based stats. Identities = 90/235 (38%), Positives = 133/235 (56%), Gaps = 7/235 (2%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSH-RDLRTGLVVLGAHV 92 I+GG E H+RPYMASV+ G H CGG LL +WV+SAAHC D + V+LGAH Sbjct: 1 ILGGQEAAAHARPYMASVQVNGTHVCGGTLLDEQWVLSAAHCMDGVTDDDSVQVLLGAHS 60 Query: 93 LSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARPPT 152 LS EP ++ + + ++ HP P + +D+ L +L+ +A LGP V L + Sbjct: 61 LSAPEPYKRWYDVQSVVPHPGSRPDSLEDDLILFKLSQNASLGPHVRPLPL-QYEDKEVE 119 Query: 153 AGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCN--SSWKGHLTLTMLCTRSGDSHR 210 GT C VAGWG V+ P L + +V +++ CN + G +T+ M+C +S+R Sbjct: 120 PGTLCDVAGWGVVTHAGRRPDVLHQLRVSIMNRTTCNLRTYHDGVVTINMMCA---ESNR 176 Query: 211 RGFCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVRRS 265 R C DSG PLVC + G+V++ CG+ K P VYT+VS++ WI ++ + Sbjct: 177 RDTCRGDSGSPLVCGDAVEGVVTWGSRVCGNGKKPGVYTRVSSYRMWIENITNGN 231 >6QHB-A nrPDB Length = 223 Score = 274 bits (701), Expect = 3e-74, Method: Composition-based stats. Identities = 73/229 (31%), Positives = 104/229 (45%), Gaps = 9/229 (3%) Query: 37 GHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVLSTA 96 G S PY A++ G CGG L+ WV++AAHC V LG H L Sbjct: 4 GGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTAAHC----KKPNLQVFLGKHNLGQQ 59 Query: 97 EPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARPPTAGTR 156 E +Q+ + HPDY +H DI LLRL A L + L T Sbjct: 60 ESSQEQSSVVRAVIHPDYDAASHDQDIMLLRLARPAKLSELIQPLPL---ERDCSAQTTS 116 Query: 157 CRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWKGHLTLTMLCTRSGDSHRRGFCSA 216 C + GWG +D + P + A + ++ + C ++ G +T MLC + + + C Sbjct: 117 CHILGWGKTADGD-FPDTIQCAYIHLVSREECEHAYPGQITQNMLCAGD-EKYGKDSCQG 174 Query: 217 DSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVRRS 265 DSGGPLVC + GLVS+ + CG + P VYT V + WI ++ Sbjct: 175 DSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQKTIQAK 223 >3LC3-A nrPDB Length = 235 Score = 274 bits (700), Expect = 4e-74, Method: Composition-based stats. Identities = 62/237 (26%), Positives = 97/237 (40%), Gaps = 11/237 (4%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVL 93 ++GG + P P+ + CGG ++ +W+V+AAHC VV G H + Sbjct: 1 VVGGEDAKPGQFPWQVVLNGKVDAFCGGSIVNEKWIVTAAHCVETGVK--ITVVAGEHNI 58 Query: 94 STAEPTQQVFGIDALTTHPDYHPM--THANDICLLRLNGSAVLGPAVGLLRPPGRRARPP 151 E T+Q + + H +Y+ + +DI LL L+ VL V + + Sbjct: 59 EETEHTEQKRNVIRIIPHHNYNAAINKYNHDIALLELDEPLVLNSYVTPICIADKEYTNI 118 Query: 152 TAGT-RCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWKGHLTLTMLCTRSGDSHR 210 V+GWG V L +V ++D C S K + M C + R Sbjct: 119 FLKFGSGYVSGWGRVFHKGRSALVLQYLRVPLVDRATCLRSTKFTIYNNMFCAGFHEGGR 178 Query: 211 RGFCSADSGGPLVCRNR----AHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVR 263 C DSGGP V G++S+ G C +YT+VS +V WI + + Sbjct: 179 -DSCQGDSGGPHVTEVEGTSFLTGIISW-GEECAMKGKYGIYTKVSRYVNWIKEKTK 233 >2AIQ-A nrPDB Length = 231 Score = 274 bits (700), Expect = 4e-74, Method: Composition-based stats. Identities = 72/240 (30%), Positives = 107/240 (44%), Gaps = 12/240 (5%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVL 93 +IGG E + ++A V G CGG L+ WV++A HC D + LG H L Sbjct: 1 VIGGDECNINEHRFLALVYANGS-LCGGTLINQEWVLTARHC----DRGNMRIYLGMHNL 55 Query: 94 STAEPTQ-QVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARPPT 152 + F + + DI L+RLN + L P PP+ Sbjct: 56 KVLNKDALRRFPKEKYFCLNTRNDTIWDKDIMLIRLNRPVRNSAHIAPLSLPS---NPPS 112 Query: 153 AGTRCRVAGWGF-VSDFEELPPGLMEAKVRVLDPDVCNSSWKGHLTLTMLCTRSGDSHRR 211 G+ CR+ GWG S LP A + +LD VC +++KG L T LC + + Sbjct: 113 VGSVCRIMGWGTITSPNATLPDVPHCANINILDYAVCQAAYKG-LAATTLCAGILEGGK- 170 Query: 212 GFCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVRRSSPQPGP 271 C DSGGPL+C + G++S G C P+ P +YT+V + WI ++ ++ P Sbjct: 171 DTCKGDSGGPLICNGQFQGILSVGGNPCAQPRKPGIYTKVFDYTDWIQSIISGNTDATCP 230 >4Z6A-H nrPDB Length = 249 Score = 273 bits (698), Expect = 7e-74, Method: Composition-based stats. Identities = 83/252 (32%), Positives = 111/252 (44%), Gaps = 10/252 (3%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSH-RDLRTGLVVLGAHV 92 I+GG P+ + G CGG L+ WVVSAAHCF ++ R + VLG H Sbjct: 1 IVGGKVCPKGECPWQVLLLVNGAQLCGGTLINTIWVVSAAHCFDKIKNWRNLIAVLGEHD 60 Query: 93 LSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARPPT 152 LS + +Q + + Y P T +DI LLRL+ VL V L P R T Sbjct: 61 LSEHDGDEQSRRVAQVIIPSTYVPGTTNHDIALLRLHQPVVLTDHVVPLCLPERTFSERT 120 Query: 153 AGTR--CRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWKGHLTLTMLCTRSGDSHR 210 V+GWG + D LM V L C +S+ G +T M C D + Sbjct: 121 LAFVRFSLVSGWGQLLDRGATALELMVLNVPRLMTQDCEASYPGKITEYMFCAGYSDGSK 180 Query: 211 RGFCSADSGGPLVCRNR----AHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVRRSS 266 C DSGGP R G+VS+ G C VYT+VS ++ W+ ++R S Sbjct: 181 -DSCKGDSGGPHATHYRGTWYLTGIVSW-GQGCATVGHFGVYTRVSQYIEWLQKLMR-SE 237 Query: 267 PQPGPLPGTTRP 278 P+PG L P Sbjct: 238 PRPGVLLRAPFP 249 >1IAU-A nrPDB Length = 227 Score = 273 bits (698), Expect = 7e-74, Method: Composition-based stats. Identities = 91/235 (38%), Positives = 120/235 (51%), Gaps = 13/235 (5%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQH---HCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGA 90 IIGGHE PHSRPYMA + Q CGGFL+R +V++AAHC+ + V LGA Sbjct: 1 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGS----SINVTLGA 56 Query: 91 HVLSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARP 150 H + EPTQQ + HP Y+P +NDI LL+L A AV LR P +A+ Sbjct: 57 HNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQ- 115 Query: 151 PTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWKGHLTLT-MLCTRSGDSH 209 G C VAGWG + + L E K+ V + C S + + T LC + Sbjct: 116 VKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIK 175 Query: 210 RRGFCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVRR 264 + F DSGGPLVC A G+VS+ + P T+VS+FV WI ++R Sbjct: 176 KTSF-KGDSGGPLVCNKVAQGIVSYGR---NNGMPPRACTKVSSFVHWIKKTMKR 226 >4DGJ-A nrPDB Length = 235 Score = 271 bits (693), Expect = 3e-73, Method: Composition-based stats. Identities = 70/235 (29%), Positives = 102/235 (43%), Gaps = 11/235 (4%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLR--TGLVVLGAH 91 I+GG + + P++ + + + CG L+ + W+VSAAHC R+L +LG H Sbjct: 1 IVGGSDAKEGAWPWVVGLYYDDRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLH 60 Query: 92 VLSTAEPTQQV-FGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARP 150 + S Q V ID + +P Y+ NDI ++ L + + P Sbjct: 61 MKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPISLPEENQVF 120 Query: 151 PTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWKGH-LTLTMLCTRSGDSH 209 P G C +AGWG V L EA V +L + C + +T M+C + Sbjct: 121 P-PGRNCSIAGWGTVVYQGTTADILQEADVPLLSNERCQQQMPEYNITENMICAGY-EEG 178 Query: 210 RRGFCSADSGGPLVCRNR----AHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWD 260 C DSGGPL+C+ G+ SF G C P P VY +VS F WI Sbjct: 179 GIDSCQGDSGGPLMCQENNRWFLAGVTSF-GYECALPNRPGVYARVSRFTEWIQS 232 >1C5M-D nrPDB Length = 255 Score = 271 bits (693), Expect = 3e-73, Method: Composition-based stats. Identities = 62/237 (26%), Positives = 98/237 (41%), Gaps = 11/237 (4%) Query: 34 IIGGHEVTPHSRPYMASV-RFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHV 92 I+GG E P+ A + + CGG +L ++++AAHC + V +G Sbjct: 1 IVGGQECKDGECPWQALLINEENEGFCGGTILSEFYILTAAHCLYQ--AKRFKVRVGDRN 58 Query: 93 LSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARPPT 152 E + V ++ + H + T+ DI +LRL V P R T Sbjct: 59 TEQEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACLPERDWAEST 118 Query: 153 AGTR--CRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWKGHLTLTMLCTRSGDSHR 210 T+ V+G+G + L +V +D + C S +T M C D+ + Sbjct: 119 LMTQKTGIVSGFGRTHEKGRQSTRLKMLEVPYVDRNSCKLSSSFIITQNMFCAGY-DTKQ 177 Query: 211 RGFCSADSGGPLVCR----NRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVR 263 C DSGGP V R G+VS+ G C +YT+V+AF+ WI ++ Sbjct: 178 EDACQGDSGGPHVTRFKDTYFVTGIVSW-GEGCARKGKYGIYTKVTAFLKWIDRSMK 233 >3DFJ-A nrPDB Length = 263 Score = 270 bits (690), Expect = 6e-73, Method: Composition-based stats. Identities = 76/251 (30%), Positives = 107/251 (42%), Gaps = 18/251 (7%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCF-SHRDLRTGLVVLGAHV 92 I GG P+ S+ + G H CGG L+ +WV+SAAHCF S V LGAH Sbjct: 1 ITGGSSAVAGQWPWQVSITYEGVHVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKLGAHQ 60 Query: 93 LSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARPPT 152 L + +V + + HP Y DI LL+L+ + + P A P Sbjct: 61 LDSYSEDAKVSTLKDIIPHPSYLQEGSQGDIALLQLSRPITFSRYIRPISLPAANASFPN 120 Query: 153 AGTRCRVAGWGFVSDFEEL--PPGLMEAKVRVLDPDVCNSSW--------KGHLTLTMLC 202 G C V GWG V+ L P L + +V ++ + CN+ + + M+C Sbjct: 121 -GLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNALYNIDAKPEEPHFVQEDMVC 179 Query: 203 TRSGDSHRRGFCSADSGGPLVCR----NRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWI 258 + + C DSGGPL C G+VS+ G CG P VYT S++ +WI Sbjct: 180 AGYVEGGK-DACQGDSGGPLSCPVEGLWYLTGIVSW-GDACGARNRPGVYTLASSYASWI 237 Query: 259 WDVVRRSSPQP 269 V P Sbjct: 238 QSKVTELQLVP 248 >5UGG-A nrPDB Length = 251 Score = 270 bits (690), Expect = 6e-73, Method: Composition-based stats. Identities = 81/242 (33%), Positives = 108/242 (44%), Gaps = 18/242 (7%) Query: 32 AQIIGGHEVTPHSRPYMASVRFG-GQHHCGGFLLRARWVVSAAHCFSHRD-LRTGLVVLG 89 +++GG PHS P+ S+R G H CGG L+ WV++AAHC + V+LG Sbjct: 20 GRVVGGCVAHPHSWPWQVSLRTRFGMHFCGGTLISPEWVLTAAHCLEKSPRPSSYKVILG 79 Query: 90 AHVLSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRAR 149 AH EP Q + L P DI LL+L+ AV+ V P Sbjct: 80 AHQEVNLEPHVQEIEVSRLFLEP------TRKDIALLKLSSPAVITDKVIPACLPS-PNY 132 Query: 150 PPTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNS--SWKGHLTLTMLCTRSGD 207 T C + GWG L EA++ V++ VCN G + T LC Sbjct: 133 VVADRTECFITGWGETQGT-FGAGLLKEAQLPVIENKVCNRYEFLNGRVQSTELCAGHL- 190 Query: 208 SHRRGFCSADSGGPLVC----RNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVR 263 + C DSGGPLVC + G+ S+ GL C P P VY +VS FV WI V+R Sbjct: 191 AGGTDSCQGDSGGPLVCFEKDKYILQGVTSW-GLGCARPNKPGVYVRVSRFVTWIEGVMR 249 Query: 264 RS 265 + Sbjct: 250 NN 251 >1MKW-K nrPDB Length = 308 Score = 269 bits (689), Expect = 7e-73, Method: Composition-based stats. Identities = 67/260 (25%), Positives = 103/260 (39%), Gaps = 27/260 (10%) Query: 31 GAQIIGGHEVTPHSRPYMASVRFGG--QHHCGGFLLRARWVVSAAHCFSHRDLR------ 82 +I+ G + P+ + + CG L+ RWV++AAHC + Sbjct: 47 EGRIVEGQDAEVGLSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTVD 106 Query: 83 TGLVVLGAHVLSTAE-PTQQVFGIDALTTHPDYHP-MTHANDICLLRLNGSAVLGPAVGL 140 LV +G H + E +++ +D + HP Y+ DI LL+L L + Sbjct: 107 DLLVRIGKHSRTRYERKVEKISMLDKIYIHPRYNWKENLDRDIALLKLKRPIELSDYIHP 166 Query: 141 LRPPGRRAR--PPTAGTRCRVAGWGF------VSDFEELPPGLMEAKVRVLDPDVCNSSW 192 + P ++ AG + RV GWG S E P L + +++ VC +S Sbjct: 167 VCLPDKQTAAKLLHAGFKGRVTGWGNRRETWTTSVAEVQPSVLQVVNLPLVERPVCKAST 226 Query: 193 KGHLTLTMLCTRS--GDSHRRGFCSADSGGPLVCR------NRAHGLVSFSGLWCGDPKT 244 + +T M C G+ R C DSGGP V + G+VS+ G C Sbjct: 227 RIRITDNMFCAGYKPGEGKRGDACEGDSGGPFVMKSPYNNRWYQMGIVSW-GEGCDRDGK 285 Query: 245 PDVYTQVSAFVAWIWDVVRR 264 YT V WI V+ R Sbjct: 286 YGFYTHVFRLKKWIQKVIDR 305 >1EKB-B nrPDB Length = 235 Score = 269 bits (687), Expect = 1e-72, Method: Composition-based stats. Identities = 69/235 (29%), Positives = 101/235 (42%), Gaps = 11/235 (4%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRD--LRTGLVVLGAH 91 I+GG + + P++ ++ F Q CG L+ W+VSAAHC R+ VLG H Sbjct: 1 IVGGSDSREGAWPWVVALYFDDQQVCGASLVSRDWLVSAAHCVYGRNMEPSKWKAVLGLH 60 Query: 92 VLST-AEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARP 150 + S P + ID + +P Y+ NDI ++ L + + P Sbjct: 61 MASNLTSPQIETRLIDQIVINPHYNKRRKNNDIAMMHLEMKVNYTDYIQPICLPEENQVF 120 Query: 151 PTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWKGH-LTLTMLCTRSGDSH 209 P G C +AGWG + L EA V +L + C + +T M+C ++ Sbjct: 121 P-PGRICSIAGWGALIYQGSTADVLQEADVPLLSNEKCQQQMPEYNITENMVCAGY-EAG 178 Query: 210 RRGFCSADSGGPLVCRNR----AHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWD 260 C DSGGPL+C+ G+ SF G C P P VY +V F WI Sbjct: 179 GVDSCQGDSGGPLMCQENNRWLLAGVTSF-GYQCALPNRPGVYARVPRFTEWIQS 232 >4H4F-A nrPDB Length = 249 Score = 268 bits (686), Expect = 2e-72, Method: Composition-based stats. Identities = 71/243 (29%), Positives = 114/243 (46%), Gaps = 18/243 (7%) Query: 34 IIGGHEVTPHSRPYMASVRF----GGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLG 89 ++GG + PHS P+ S+++ +H CGG L+ + +V++AAHC S + RT V +G Sbjct: 1 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCIS--NTRTYRVAVG 58 Query: 90 AHVLS-TAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRA 148 + L E G+D + H ++ + NDI L++L L + + P + + Sbjct: 59 KNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDS 118 Query: 149 RPPTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNS--SWKGHLTLTMLCTRSG 206 P C V GWG + + L + V+D C+ W + TM+C Sbjct: 119 LLPK-DYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGG- 176 Query: 207 DSHRRGFCSADSGGPLVCR-----NRAHGLVSFSG-LWCGDPKTPDVYTQVSAFVAWIWD 260 C+ DSGGPL C+ G+VSF C K P VYT+VSA++ WI + Sbjct: 177 -DGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINE 235 Query: 261 VVR 263 ++ Sbjct: 236 KMQ 238 >3K65-B nrPDB Length = 308 Score = 268 bits (685), Expect = 2e-72, Method: Composition-based stats. Identities = 60/260 (23%), Positives = 100/260 (38%), Gaps = 27/260 (10%) Query: 31 GAQIIGGHEVTPHSRPYMASVRFGG--QHHCGGFLLRARWVVSAAHCFSHRDL------R 82 +I+ G + P+ + + CG L+ RWV++AAHC + Sbjct: 47 DGRIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTEN 106 Query: 83 TGLVVLGAHVLSTAEPT-QQVFGIDALTTHPDYHP-MTHANDICLLRLNGSAVLGPAVGL 140 LV +G H + E +++ ++ + HP Y+ DI L++L + Sbjct: 107 DLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHP 166 Query: 141 LRPPGRRA--RPPTAGTRCRVAGWGFVSD------FEELPPGLMEAKVRVLDPDVCNSSW 192 + P R AG + RV GWG + + + P L + +++ VC S Sbjct: 167 VCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDST 226 Query: 193 KGHLTLTMLCTRSG--DSHRRGFCSADSGGPLVCR------NRAHGLVSFSGLWCGDPKT 244 + +T M C + R C D+GGP V + G+VS+ G C Sbjct: 227 RIRITDNMFCAGYKPDEGKRGDACEGDAGGPFVMKSPFNNRWYQMGIVSW-GEGCDRDGK 285 Query: 245 PDVYTQVSAFVAWIWDVVRR 264 YT V WI V+ + Sbjct: 286 YGFYTHVFRLKKWIQKVIDQ 305 >4DUR-A nrPDB Length = 791 Score = 268 bits (685), Expect = 2e-72, Method: Composition-based stats. Identities = 81/242 (33%), Positives = 108/242 (44%), Gaps = 18/242 (7%) Query: 32 AQIIGGHEVTPHSRPYMASVRFG-GQHHCGGFLLRARWVVSAAHCFSHRD-LRTGLVVLG 89 +++GG PHS P+ S+R G H CGG L+ WV++AAHC + V+LG Sbjct: 560 GRVVGGCVAHPHSWPWQVSLRTRFGMHFCGGTLISPEWVLTAAHCLEKSPRPSSYKVILG 619 Query: 90 AHVLSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRAR 149 AH EP Q + L P DI LL+L+ AV+ V P Sbjct: 620 AHQEVNLEPHVQEIEVSRLFLEP------TRKDIALLKLSSPAVITDKVIPACLPS-PNY 672 Query: 150 PPTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNS--SWKGHLTLTMLCTRSGD 207 T C + GWG L EA++ V++ VCN G + T LC Sbjct: 673 VVADRTECFITGWGETQGT-FGAGLLKEAQLPVIENKVCNRYEFLNGRVQSTELCAGHL- 730 Query: 208 SHRRGFCSADSGGPLVC----RNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVR 263 + C DSGGPLVC + G+ S+ GL C P P VY +VS FV WI V+R Sbjct: 731 AGGTDSCQGDSGGPLVCFEKDKYILQGVTSW-GLGCARPNKPGVYVRVSRFVTWIEGVMR 789 Query: 264 RS 265 + Sbjct: 790 NN 791 >3NXP-A nrPDB Length = 424 Score = 267 bits (683), Expect = 3e-72, Method: Composition-based stats. Identities = 61/260 (23%), Positives = 100/260 (38%), Gaps = 27/260 (10%) Query: 31 GAQIIGGHEVTPHSRPYMASVRFGG--QHHCGGFLLRARWVVSAAHCFSHRDL------R 82 +I+ G + P+ + + CG L+ RWV++AAHC + Sbjct: 163 DGRIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTEN 222 Query: 83 TGLVVLGAHVLSTAEPT-QQVFGIDALTTHPDYHP-MTHANDICLLRLNGSAVLGPAVGL 140 LV +G H + E +++ ++ + HP Y+ DI L++L + Sbjct: 223 DLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHP 282 Query: 141 LRPPGRRA--RPPTAGTRCRVAGWGFVSD------FEELPPGLMEAKVRVLDPDVCNSSW 192 + P R AG + RV GWG + + + P L + +++ VC S Sbjct: 283 VCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDST 342 Query: 193 KGHLTLTMLCTRSG--DSHRRGFCSADSGGPLVCR------NRAHGLVSFSGLWCGDPKT 244 + +T M C + R C DSGGP V + G+VS+ G C Sbjct: 343 RIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSW-GEGCDRDGK 401 Query: 245 PDVYTQVSAFVAWIWDVVRR 264 YT V WI V+ + Sbjct: 402 YGFYTHVFRLKKWIQKVIDQ 421 >1NN6-A nrPDB Length = 228 Score = 267 bits (683), Expect = 4e-72, Method: Composition-based stats. Identities = 88/238 (36%), Positives = 121/238 (50%), Gaps = 14/238 (5%) Query: 32 AQIIGGHEVTPHSRPYMASVRF----GGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVV 87 +IIGG E PHSRPYMA + G CGGFL+R +V++AAHC R+ V Sbjct: 1 GEIIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHC----AGRSITVT 56 Query: 88 LGAHVLSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRR 147 LGAH ++ E T Q + HP Y+ T +DI LL+L A L AVG L P + Sbjct: 57 LGAHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQF 116 Query: 148 ARPPTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWKGHLTLTMLCTRSGD 207 P G CRVAGWG + L E K+R++DP C S ++ LC + Sbjct: 117 NFVP-PGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQAC-SHFRDFDHNLQLCVGNPR 174 Query: 208 SHRRGFCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVRRS 265 + DSGGPL+C A G+VS+ D K P V+T++S + WI +++ + Sbjct: 175 KTK-SAFKGDSGGPLLCAGVAQGIVSYGRS---DAKPPAVFTRISHYRPWINQILQAN 228 >1OP0-A nrPDB Length = 234 Score = 267 bits (682), Expect = 5e-72, Method: Composition-based stats. Identities = 64/241 (26%), Positives = 100/241 (41%), Gaps = 11/241 (4%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVL 93 +IGG+E + ++ + CGG L+ WVV+AAHC D + LG H Sbjct: 1 VIGGNECDINEHRFLVAFFNTTGFFCGGTLINPEWVVTAAHC----DSTDFQMQLGVHSK 56 Query: 94 STAEPTQQVFGIDALTTHPDYHPMT-HANDICLLRLNGSAVLGPAVGLLRPPGRRARPPT 152 +Q P+ + DI L++L+ + L + PP+ Sbjct: 57 KVLNEDEQTRNPKEKFICPNKNNNEVLDKDIMLIKLDKPISNSKHIAPL---SLPSSPPS 113 Query: 153 AGTRCRVAGWGFVSD-FEELPPGLMEAKVRVLDPDVCNSSWKGHLTL-TMLCTRSGDSHR 210 G+ CR+ GWG ++ E P A + +LD VC + + L LC + Sbjct: 114 VGSVCRIMGWGSITPVKETFPDVPYCANINLLDHAVCQAGYPELLAEYRTLCAGIVQGGK 173 Query: 211 RGFCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVRRSSPQPG 270 C DSGGPL+C + G+VS+ CG P +YT V + WI + ++ Sbjct: 174 -DTCGGDSGGPLICNGQFQGIVSYGAHPCGQGPKPGIYTNVFDYTDWIQRNIAGNTDATC 232 Query: 271 P 271 P Sbjct: 233 P 233 >4NZQ-A nrPDB Length = 557 Score = 266 bits (680), Expect = 1e-71, Method: Composition-based stats. Identities = 61/260 (23%), Positives = 100/260 (38%), Gaps = 27/260 (10%) Query: 31 GAQIIGGHEVTPHSRPYMASVRFGG--QHHCGGFLLRARWVVSAAHCFSHRDL------R 82 +I+ G + P+ + + CG L+ RWV++AAHC + Sbjct: 296 DGRIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTEN 355 Query: 83 TGLVVLGAHVLSTAEPT-QQVFGIDALTTHPDYHP-MTHANDICLLRLNGSAVLGPAVGL 140 LV +G H + E +++ ++ + HP Y+ DI L++L + Sbjct: 356 DLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHP 415 Query: 141 LRPPGRRA--RPPTAGTRCRVAGWGFVSD------FEELPPGLMEAKVRVLDPDVCNSSW 192 + P R AG + RV GWG + + + P L + +++ VC S Sbjct: 416 VCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDST 475 Query: 193 KGHLTLTMLCTRSG--DSHRRGFCSADSGGPLVCR------NRAHGLVSFSGLWCGDPKT 244 + +T M C + R C DSGGP V + G+VS+ G C Sbjct: 476 RIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSW-GEGCDRDGK 534 Query: 245 PDVYTQVSAFVAWIWDVVRR 264 YT V WI V+ + Sbjct: 535 YGFYTHVFRLKKWIQKVIDQ 554 >1BQY-A nrPDB Length = 234 Score = 266 bits (680), Expect = 1e-71, Method: Composition-based stats. Identities = 67/241 (27%), Positives = 101/241 (41%), Gaps = 11/241 (4%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVL 93 + GG E + + + CGG L+ WVV+AAHC D ++ G H Sbjct: 1 VFGGDECNINEHRSLVVLFNSNGFLCGGTLINQDWVVTAAHC----DSNNFQLLFGVHSK 56 Query: 94 STAEPTQQVFGIDALTTHPDYH-PMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARPPT 152 +Q P+ DI L++L+ S + L + PP+ Sbjct: 57 KILNEDEQTRDPKEKFFCPNRKKDDEVDKDIMLIKLDSSVSNSEHIAPL---SLPSSPPS 113 Query: 153 AGTRCRVAGWGFVSDFEE-LPPGLMEAKVRVLDPDVCNSSWK-GHLTLTMLCTRSGDSHR 210 G+ CR+ GWG +E P A + +LD VC +++ + T LC R Sbjct: 114 VGSVCRIMGWGKTIPTKEIYPDVPHCANINILDHAVCRTAYSWRQVANTTLCAGILQGGR 173 Query: 211 RGFCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVRRSSPQPG 270 C DSGGPL+C G+VS+ G CG P P VYT+V ++ WI ++ + Sbjct: 174 -DTCHFDSGGPLICNGIFQGIVSWGGHPCGQPGEPGVYTKVFDYLDWIKSIIAGNKDATC 232 Query: 271 P 271 P Sbjct: 233 P 233 >4E7N-A nrPDB Length = 238 Score = 265 bits (679), Expect = 1e-71, Method: Composition-based stats. Identities = 59/245 (24%), Positives = 99/245 (40%), Gaps = 15/245 (6%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQ--HHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAH 91 IIGG E + ++ ++ CGG L+ WV++AAHC D + + LG H Sbjct: 1 IIGGDECNINEHRFLVALYTSRSRTLFCGGTLINQEWVLTAAHC----DRKNFRIKLGMH 56 Query: 92 VLSTAEPTQQVFGIDALTTH-PDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARP 150 +Q + DI L+RL+ + + P Sbjct: 57 SKKVPNEDEQTRVPKEKFFCLSSKNYTLWDKDIMLIRLDSPVKNSKHIAPF---SLPSSP 113 Query: 151 PTAGTRCRVAGWGFVSDF-EELPPGLMEAKVRVLDPDVCNSSWKGH---LTLTMLCTRSG 206 P+ G+ CR+ GWG +S P + +L+ ++C + + T LC Sbjct: 114 PSVGSVCRIMGWGRISPTEGTYPDVPHCVNINLLEYEMCRAPYPEFELPATSRTLCAGIL 173 Query: 207 DSHRRGFCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVRRSS 266 + + C DSGGPL+C + G+ S+ C P P YT+V + WI +++ ++ Sbjct: 174 EGGK-DTCKGDSGGPLICNGQFQGIASWGDDPCAQPHKPAAYTKVFDHLDWIENIIAGNT 232 Query: 267 PQPGP 271 P Sbjct: 233 DASCP 237 >4MPW-A nrPDB Length = 245 Score = 265 bits (679), Expect = 1e-71, Method: Composition-based stats. Identities = 76/246 (30%), Positives = 111/246 (45%), Gaps = 28/246 (11%) Query: 34 IIGGHEVTPHSRPYMASVRFGG---QHHCGGFLLRARWVVSAAHCFSH--RDLRTGLVVL 88 I+GG E P+ S+R G H CGG L+ +WV++AAHC +DL V L Sbjct: 1 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 60 Query: 89 GAHVLSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRA 148 L + Q+ + + HP ++ DI LL L + V + P Sbjct: 61 REQHLYYQD---QLLPVSRIIVHPQFYTAQIGADIALLELEEPVKVSSHVHTVTLPPASE 117 Query: 149 RPPTAGTRCRVAGWGFVSDFEELPP--GLMEAKVRVLDPDVCNSSWK---------GHLT 197 P G C V GWG V + E LPP L + KV +++ +C++ + + Sbjct: 118 TFP-PGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVR 176 Query: 198 LTMLCTRSGDSHRRGFCSADSGGPLVCRNRAH----GLVSFSGLWCGDPKTPDVYTQVSA 253 MLC + RR C DSGGPLVC+ G+VS+ G C P P +YT+V+ Sbjct: 177 DDMLCAGN---TRRDSCQGDSGGPLVCKVNGTWLQAGVVSW-GEGCAQPNRPGIYTRVTY 232 Query: 254 FVAWIW 259 ++ WI Sbjct: 233 YLDWIH 238 >3S69-A nrPDB Length = 234 Score = 265 bits (677), Expect = 2e-71, Method: Composition-based stats. Identities = 63/242 (26%), Positives = 100/242 (41%), Gaps = 11/242 (4%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVL 93 +IGG E + + + C G L+ WV++AAHC D + LG H Sbjct: 1 VIGGDECNINEHRSLVAFFNSTGFFCSGTLINEEWVLTAAHC----DNTNFQMKLGVHSK 56 Query: 94 STAEPTQQVFGIDALTTHPDY-HPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARPPT 152 +Q P+ + DI L++L+ + L + PP+ Sbjct: 57 KVLNEDEQTRNPKEKFICPNKKNDEVLDKDIMLIKLDSRVSNSEHIVPL---SLPSSPPS 113 Query: 153 AGTRCRVAGWGFVSDFE-ELPPGLMEAKVRVLDPDVCNSSWKGHLTL-TMLCTRSGDSHR 210 G+ C + GWG ++ + P A + +LD VC + + LT LC + + Sbjct: 114 VGSVCHIMGWGSITPIKVTYPDVPYCAYINLLDDAVCQAGYPELLTEYRTLCAGILEGGK 173 Query: 211 RGFCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVRRSSPQPG 270 C DSGGPL+C + G+VSF CG P VYT+V + WI ++ ++ Sbjct: 174 -DTCGGDSGGPLICNGQFQGIVSFGAHPCGQGLKPGVYTKVFDYNHWIQSIIAGNTTVTC 232 Query: 271 PL 272 P Sbjct: 233 PQ 234 >1FUJ-A nrPDB Length = 221 Score = 264 bits (675), Expect = 3e-71, Method: Composition-based stats. Identities = 85/233 (36%), Positives = 117/233 (50%), Gaps = 15/233 (6%) Query: 34 IIGGHEVTPHSRPYMASVRFGG---QHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGA 90 I+GGHE PHSRPYMAS++ G H CGG L+ +V++AAHC R VVLGA Sbjct: 1 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 60 Query: 91 HVLSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARP 150 H + T EPTQQ F + + + +Y NDI L++L+ A L +V ++ P + +P Sbjct: 61 HNVRTQEPTQQHFSVAQVFLN-NYDAENKLNDILLIQLSSPANLSASVATVQLPQQD-QP 118 Query: 151 PTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWKGHLTLTMLCTRSGDSHR 210 GT+C GWG V + L E V V+ C +CT + Sbjct: 119 VPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVTF-FCRPH--------NICTFVPR-RK 168 Query: 211 RGFCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVR 263 G C DSGGPL+C G+ SF C PD +T+V+ +V WI +R Sbjct: 169 AGICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTLR 221 >3P8G-A nrPDB Length = 241 Score = 263 bits (673), Expect = 6e-71, Method: Composition-based stats. Identities = 71/240 (29%), Positives = 97/240 (40%), Gaps = 16/240 (6%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQ-HHCGGFLLRARWVVSAAHC------FSHRDLRTGLV 86 ++GG + P+ S+ GQ H CG L+ W+VSAAHC F + D Sbjct: 1 VVGGTDADEGEWPWQVSLHALGQGHICGASLISPNWLVSAAHCYIDDRGFRYSDPTQWTA 60 Query: 87 VLGAHVLSTAE-PTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPG 145 LG H S P Q + + +HP ++ T DI LL L A V + P Sbjct: 61 FLGLHDQSQRSAPGVQERRLKRIISHPFFNDFTFDYDIALLELEKPAEYSSMVRPICLPD 120 Query: 146 RRARPPTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWKGHLTLTMLCTRS 205 P AG V GWG L + ++RV+ C + +T M+C Sbjct: 121 ASHVFP-AGKAIWVTGWGHTQYGGTGALILQKGEIRVIQQTTCENLLPQQITPRMMCVGF 179 Query: 206 GDSHRRGFCSADSGGPLV---CRNR--AHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWD 260 S C DSGGPL R G+VS+ G C P VYT++ F WI + Sbjct: 180 L-SGGVDSCQGDSGGPLSSVEADGRIFQAGVVSW-GDGCAQRNKPGVYTRLPLFRDWIKE 237 >3G01-A nrPDB Length = 227 Score = 263 bits (673), Expect = 6e-71, Method: Composition-based stats. Identities = 94/235 (40%), Positives = 127/235 (54%), Gaps = 14/235 (5%) Query: 34 IIGGHEVTPHSRPYMA---SVRFGGQH-HCGGFLLRARWVVSAAHCFSHRDLRTGLVVLG 89 IIGG+E++PHSRPYMA ++ GG+ CGGFL+R ++V++AAHC R+ V LG Sbjct: 1 IIGGNEISPHSRPYMAYYEFLKVGGKKMFCGGFLVRDKFVLTAAHC----KGRSMTVTLG 56 Query: 90 AHVLSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRAR 149 AH + E TQQ+ + HPDY+P +NDI LL+L +A AV L P R A Sbjct: 57 AHNIKAKEETQQIIPVAKAIPHPDYNPDDRSNDIMLLKLVRNAKRTRAVRPLNLPRRNAH 116 Query: 150 PPTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWKGHL-TLTMLCTRSGDS 208 G C VAGWG V+ E P L E K+ V VC S ++ +C Sbjct: 117 -VKPGDECYVAGWGKVTPDGEFPKTLHEVKLTVQKDQVCESQFQSSYNRANEICVGDSKI 175 Query: 209 HRRGFCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVR 263 F DSGGPLVC+ A G+VS+ D P V+T+V +FV+WI ++ Sbjct: 176 KGASF-RGDSGGPLVCKRAAAGIVSYGQT---DGSAPQVFTRVLSFVSWIKKTMK 226 >1ETT-H nrPDB Length = 259 Score = 263 bits (672), Expect = 6e-71, Method: Composition-based stats. Identities = 67/257 (26%), Positives = 102/257 (39%), Gaps = 27/257 (10%) Query: 34 IIGGHEVTPHSRPYMASVRFGG--QHHCGGFLLRARWVVSAAHCFSHRDLR------TGL 85 I+ G + P+ + + CG L+ RWV++AAHC + L Sbjct: 1 IVEGQDAEVGLSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTVDDLL 60 Query: 86 VVLGAHVLSTAE-PTQQVFGIDALTTHPDYHP-MTHANDICLLRLNGSAVLGPAVGLLRP 143 V +G H + E +++ +D + HP Y+ DI LL+L L + + Sbjct: 61 VRIGKHSRTRYERKVEKISMLDKIYIHPRYNWKENLDRDIALLKLKRPIELSDYIHPVCL 120 Query: 144 PGRRAR--PPTAGTRCRVAGWGF------VSDFEELPPGLMEAKVRVLDPDVCNSSWKGH 195 P ++ AG + RV GWG S E P L + +++ VC +S + Sbjct: 121 PDKQTAAKLLHAGFKGRVTGWGNRRETWTTSVAEVQPSVLQVVNLPLVERPVCKASTRIR 180 Query: 196 LTLTMLCTRS--GDSHRRGFCSADSGGPLVCR------NRAHGLVSFSGLWCGDPKTPDV 247 +T M C G+ R C DSGGP V + G+VS+ G C Sbjct: 181 ITDNMFCAGYKPGEGKRGDACEGDSGGPFVMKSPYNNRWYQMGIVSW-GEGCDRDGKYGF 239 Query: 248 YTQVSAFVAWIWDVVRR 264 YT V WI V+ R Sbjct: 240 YTHVFRLKKWIQKVIDR 256 >1PYT-D nrPDB Length = 251 Score = 263 bits (672), Expect = 7e-71, Method: Composition-based stats. Identities = 76/257 (29%), Positives = 120/257 (46%), Gaps = 19/257 (7%) Query: 19 LMLPVKPPAGSWGAQIIGGHEVTPHSRPYMASVRF----GGQHHCGGFLLRARWVVSAAH 74 P+ P S A+++GG + PHS P+ S+++ +H CGG L+ V++AAH Sbjct: 1 CGAPIFQPNLS--ARVVGGEDAIPHSWPWQISLQYLRDNTWRHTCGGTLITPNHVLTAAH 58 Query: 75 CFSHRDLRTGLVVLGAHVLSTAEPTQQVF-GIDALTTHPDYHPMTHANDICLLRLNGSAV 133 C S+ T V LG + L + ++ G+D + H ++ NDI L++L + Sbjct: 59 CISNTL--TYRVALGKNNLEVEDEAGSLYVGVDTIFVHEKWNSFLVRNDIALIKLAETVE 116 Query: 134 LGPAVGLLRPPGRRARPPTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNS--S 191 LG + + P + P C V GWG + + L + V+D C+ Sbjct: 117 LGDTIQVACLPSEGSLLPQ-DYPCFVTGWGRLYTNGPIAAELQQGLQPVVDYATCSQRDW 175 Query: 192 WKGHLTLTMLCTRSGDSHRRGFCSADSGGPLVCRNRAH----GLVSFS-GLWCGDPKTPD 246 W + TM+C C+ DSGGPL C+ G+VSF GL C K P Sbjct: 176 WGTTVKETMVCAGG--DGVISACNGDSGGPLNCQADGQWDVRGIVSFGSGLSCNTFKKPT 233 Query: 247 VYTQVSAFVAWIWDVVR 263 V+T+VSA++ WI ++ Sbjct: 234 VFTRVSAYIDWINQKLQ 250 >2F91-A nrPDB Length = 237 Score = 263 bits (672), Expect = 8e-71, Method: Composition-based stats. Identities = 65/238 (27%), Positives = 101/238 (42%), Gaps = 17/238 (7%) Query: 34 IIGGHEVTPHSRPYMASVRFG----GQHHCGGFLLRARWVVSAAHCFSHRDLRT---GLV 86 I+GG + T PY S + H CG + + ++A HC D + Sbjct: 1 IVGGTDATLGEFPYQLSFQETFIGFSFHFCGASIYNENYAITAGHCVYGDDYENPSGLQI 60 Query: 87 VLGAHVLSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGR 146 V G +S E ++Q+ + + H ++ NDI LL+L+GS V + P + Sbjct: 61 VAGELDMSVNEGSEQIITVSKIILHENFDYNLLDNDISLLKLSGSLTFNDNVAPIALPEQ 120 Query: 147 RARPPTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWK-GHLTLTMLCTRS 205 TA V GWG S+ P L + V ++ + C + + + +M+C Sbjct: 121 GH---TATGDVIVTGWGTTSEGGNTPDVLQKVTVPLVSDEDCRADYGADEILDSMICAGV 177 Query: 206 GDSHRRGFCSADSGGPLVCRNR----AHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIW 259 + + C DSGGPL + G+VS+ G C P P VYT+VS V WI Sbjct: 178 PEGGK-DSCQGDSGGPLAASDTGSTYLAGIVSW-GYGCARPGYPGVYTEVSYHVDWIK 233 >1VR1-H nrPDB Length = 261 Score = 262 bits (671), Expect = 8e-71, Method: Composition-based stats. Identities = 62/261 (23%), Positives = 100/261 (38%), Gaps = 31/261 (11%) Query: 34 IIGGHEVTPHSRPYMASVRF------GGQHHCGGFLLRARWVVSAAHCFSHRDL------ 81 I+ G + P+ + G + CG L+ RWV++AAHC + Sbjct: 1 IVEGSDAEIGMSPWQVMLFAKHRRSPGERFLCGASLISDRWVLTAAHCLLYPPWDKNFTE 60 Query: 82 RTGLVVLGAHVLSTAEPT-QQVFGIDALTTHPDYHP-MTHANDICLLRLNGSAVLGPAVG 139 LV +G H + E +++ ++ + HP Y+ DI L++L + Sbjct: 61 NDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIH 120 Query: 140 LLRPPGRRA--RPPTAGTRCRVAGWGFVSD------FEELPPGLMEAKVRVLDPDVCNSS 191 + P R AG + RV GWG + + + P L + +++ VC S Sbjct: 121 PVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDS 180 Query: 192 WKGHLTLTMLCTRSG--DSHRRGFCSADSGGPLVCR------NRAHGLVSFSGLWCGDPK 243 + +T M C + R C DSGGP V + G+VS+ G C Sbjct: 181 TRIRITDNMFCAYYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSW-GEGCDRDG 239 Query: 244 TPDVYTQVSAFVAWIWDVVRR 264 YT V WI V+ + Sbjct: 240 KYGFYTHVFRLKKWIQKVIDQ 260 >2OCV-B nrPDB Length = 259 Score = 261 bits (668), Expect = 2e-70, Method: Composition-based stats. Identities = 64/257 (24%), Positives = 103/257 (40%), Gaps = 27/257 (10%) Query: 34 IIGGHEVTPHSRPYMASVRFGG--QHHCGGFLLRARWVVSAAHCFSHRDL------RTGL 85 I+ G + P+ + + CG L+ RWV++AAHC + L Sbjct: 1 IVEGWDAEKGIAPWQVMLFRKSPQELLCGASLISDRWVLTAAHCILYPPWDKNFTENDLL 60 Query: 86 VVLGAHVLSTAEPT-QQVFGIDALTTHPDYHP-MTHANDICLLRLNGSAVLGPAVGLLRP 143 V +G H + E +++ ++ + HP Y+ DI LL+L + + Sbjct: 61 VRIGKHSRTRYERNVEKISMLEKIYVHPRYNWRENLDRDIALLKLKKPVPFSDYIHPVCL 120 Query: 144 PGRRA--RPPTAGTRCRVAGWGFVSD------FEELPPGLMEAKVRVLDPDVCNSSWKGH 195 P ++ AG + RV GWG + + E P L + +++ VC +S + Sbjct: 121 PDKQTVTSLLRAGYKGRVTGWGNLRETWTTNINEIQPSVLQVVNLPIVERPVCKASTRIR 180 Query: 196 LTLTMLCTRS--GDSHRRGFCSADSGGPLVCR------NRAHGLVSFSGLWCGDPKTPDV 247 +T M C D+ R C DSGGP V + G+VS+ G C Sbjct: 181 ITDNMFCAGFKVNDTKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSW-GEGCDRKGKYGF 239 Query: 248 YTQVSAFVAWIWDVVRR 264 YT V AWI V+ + Sbjct: 240 YTHVFRLKAWIQKVIDQ 256 >1BDA-A nrPDB Length = 265 Score = 261 bits (667), Expect = 3e-70, Method: Composition-based stats. Identities = 80/277 (28%), Positives = 114/277 (41%), Gaps = 32/277 (11%) Query: 4 GLRGWGRPLLTVATALMLPVKPPAGSWGAQIIGGHEVTPHSRPYMASVRFGGQHHCGGFL 63 GLR + +P + L + + W A I H +P + CGG L Sbjct: 3 GLRQYSQPQFRIKGGLFADI--ASHPWQAAIFAKHRRSPGE-----------RFLCGGIL 49 Query: 64 LRARWVVSAAHCFSHR-DLRTGLVVLGAHVLSTAEPTQQVFGIDALTTHPDYHPMTHAND 122 + + W++SAAHCF R V+LG +Q F ++ H ++ T+ ND Sbjct: 50 ISSCWILSAAHCFQERFPPHHLTVILGRTYRVVPGEEEQKFEVEKYIVHKEFDDDTYDND 109 Query: 123 ICLLRLNGS----AVLGPAVGLLRPPGRRARPPTAGTRCRVAGWGFVSDFEE-LPPGLME 177 I LL+L A V + P + P T C ++G+G L E Sbjct: 110 IALLQLKSDSSRCAQESSVVRTVCLPPADLQLPD-WTECELSGYGKHEALSPFYSERLKE 168 Query: 178 AKVRVLDPDVCNSSW--KGHLTLTMLCTRSGDSHR-----RGFCSADSGGPLVC----RN 226 A VR+ C S +T MLC S C DSGGPLVC R Sbjct: 169 AHVRLYPSSRCTSQHLLNRTVTDNMLCAGDTRSGGPQANLHDACQGDSGGPLVCLNDGRM 228 Query: 227 RAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVR 263 G++S+ GL CG P VYT+V+ ++ WI D +R Sbjct: 229 TLVGIISW-GLGCGQKDVPGVYTKVTNYLDWIRDNMR 264 >2V35-A nrPDB Length = 240 Score = 261 bits (667), Expect = 3e-70, Method: Composition-based stats. Identities = 78/245 (31%), Positives = 117/245 (47%), Gaps = 18/245 (7%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQ----HHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLG 89 ++GG E +S P S+++ H CGG L+R WV++AAHC T VV+G Sbjct: 1 VVGGTEAQRNSWPSQISLQYRSGSSWAHTCGGTLIRQNWVMTAAHCVDREL--TFRVVVG 58 Query: 90 AHVLSTAEPTQQVFGIDALTTHPDYHPMTH--ANDICLLRLNGSAVLGPAVGLLRPPGRR 147 H L+ + T+Q G+ + HP ++ DI LLRL S L V L P R Sbjct: 59 EHNLNQNDGTEQYVGVQKIVVHPYWNTDDVAAGYDIALLRLAQSVTLNSYVQLGVLP-RA 117 Query: 148 ARPPTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSS--WKGHLTLTMLCTRS 205 + C + GWG +L L +A + +D +C+SS W + +M+C Sbjct: 118 GTILANNSPCYITGWGLTRTNGQLAQTLQQAYLPTVDYAICSSSSYWGSTVKNSMVCAGG 177 Query: 206 GDSHRRGFCSADSGGPLVC----RNRAHGLVSFSGL-WCGDPKTPDVYTQVSAFVAWIWD 260 R C DSGGPL C + HG+ SF C + P V+T+VSA+++WI + Sbjct: 178 --DGVRSGCQGDSGGPLHCLVNGQYAVHGVTSFVSRLGCNVTRKPTVFTRVSAYISWINN 235 Query: 261 VVRRS 265 V+ + Sbjct: 236 VIASN 240 >1LTO-A nrPDB Length = 245 Score = 261 bits (667), Expect = 3e-70, Method: Composition-based stats. Identities = 74/246 (30%), Positives = 112/246 (45%), Gaps = 28/246 (11%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQ---HHCGGFLLRARWVVSAAHCFSH--RDLRTGLVVL 88 I+GG E P+ S+R + H CGG L+ +WV++AAHC +DL T V L Sbjct: 1 IVGGQEAPRSKWPWQVSLRVRDRYWMHFCGGSLIHPQWVLTAAHCLGPDVKDLATLRVQL 60 Query: 89 GAHVLSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRA 148 L + Q+ + + HP ++ + DI LL L + V + P Sbjct: 61 REQHLYYQD---QLLPVSRIIVHPQFYIIQTGADIALLELEEPVNISSRVHTVMLPPASE 117 Query: 149 RPPTAGTRCRVAGWGFVSDFEELPP--GLMEAKVRVLDPDVCNSSWK---------GHLT 197 P G C V GWG V + E LPP L + KV +++ +C++ + + Sbjct: 118 TFP-PGMPCWVTGWGDVDNDEPLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIIR 176 Query: 198 LTMLCTRSGDSHRRGFCSADSGGPLVCRNRAH----GLVSFSGLWCGDPKTPDVYTQVSA 253 MLC + +R C DSGGPLVC+ G+VS+ C P P +YT+V+ Sbjct: 177 DDMLCAGNS---QRDSCKGDSGGPLVCKVNGTWLQAGVVSW-DEGCAQPNRPGIYTRVTY 232 Query: 254 FVAWIW 259 ++ WI Sbjct: 233 YLDWIH 238 >2BDH-A nrPDB Length = 223 Score = 260 bits (665), Expect = 5e-70, Method: Composition-based stats. Identities = 76/232 (32%), Positives = 114/232 (49%), Gaps = 10/232 (4%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVL 93 II G + +PHS+P+ A++ + C G L+ +WV+SAAHCF + + LG H L Sbjct: 1 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQ----NSYTIGLGLHSL 56 Query: 94 S-TAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARPPT 152 EP Q+ HP+Y+ AND+ L++L+ S + + ++ PT Sbjct: 57 EADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSI---SIASQCPT 113 Query: 153 AGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWKGHLTLTMLCTRSGDSHRRG 212 AG C V+GWG +++ +P L V V+ +VC+ + +M C G + Sbjct: 114 AGNSCLVSGWGLLAN-GRMPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGQDQK-D 171 Query: 213 FCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVRR 264 C+ DSGGPL+C GLVSF CG P VYT + F WI V+ Sbjct: 172 SCNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQA 223 >1FIZ-A nrPDB Length = 263 Score = 260 bits (664), Expect = 6e-70, Method: Composition-based stats. Identities = 79/267 (29%), Positives = 125/267 (46%), Gaps = 26/267 (9%) Query: 34 IIGGHEVTPHSRPYMASVRF------GGQHHCGGFLLRARWVVSAAHCFSHRDL-RTGLV 86 ++GG P + P+M S++ H CGG LL + WV++AAHCF ++ + Sbjct: 1 VVGGMSAEPGAWPWMVSLQIFMYHNNRRYHTCGGILLNSHWVLTAAHCFKNKKKVTDWRL 60 Query: 87 VLGAHVLSTAE-----PTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLL 141 + GA+ + P Q ++ + H Y NDI L+++ GP +G Sbjct: 61 IFGANEVVWGSNKPVKPPLQERFVEEIIIHEKYVSGLEINDIALIKITPPVPCGPFIGPG 120 Query: 142 RPPGRRARPPTAGTRCRVAGWGFVSDFE-ELPPGLMEAKVRVLDPDVCNS--SWKGHLTL 198 P +A PP A C V GWG++ + P L EA+V ++D ++CNS + G + Sbjct: 121 CLPQFKAGPPRAPQTCWVTGWGYLKEKGPRTSPTLQEARVALIDLELCNSTRWYNGRIRS 180 Query: 199 TMLCTRSGDSHRRGFCSADSGGPLVCRNRAH------GLVSFSGLWCGDPKTPDVYTQVS 252 T +C + C DSGGPL+CR+RA G+ S+ G+ C K P VYT Sbjct: 181 TNVCAGYPRG-KIDTCQGDSGGPLMCRDRAENTFVVVGITSW-GVGCARAKRPGVYTSTW 238 Query: 253 AFVAWIWDVVRRSSPQPGPLPGTTRPP 279 ++ WI + ++ Q + PP Sbjct: 239 PYLNWIASKIGSNALQ---MVQLGTPP 262 >1ORF-A nrPDB Length = 234 Score = 260 bits (664), Expect = 7e-70, Method: Composition-based stats. Identities = 82/236 (34%), Positives = 120/236 (50%), Gaps = 11/236 (4%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVL 93 IIGG+EVTPHSRPYM + + C G L+ WV++AAHC + V+LGAH + Sbjct: 1 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHC---NLNKRSQVILGAHSI 57 Query: 94 STAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARPPTA 153 + EPT+Q+ + +P Y P T D+ LL+L A + V +L P ++ Sbjct: 58 TREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLTEKAKINKYVTILHLP-KKGDDVKP 116 Query: 154 GTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSS----WKGHLTLTMLCTRSGDSH 209 GT C+VAGWG + L E ++ ++D VCN + + + M+C S Sbjct: 117 GTMCQVAGWGRTHNSASWSDTLREVEITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGG 176 Query: 210 RRGFCSADSGGPLVCRNRAHGLVSFSGLW-CGDPKTPDVYTQVS-AFVAWIWDVVR 263 R C+ DSG PL+C G+ SF CGDP+ P VY +S + WI ++ Sbjct: 177 R-DSCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTIK 231 >3TK9-A nrPDB Length = 226 Score = 259 bits (663), Expect = 7e-70, Method: Composition-based stats. Identities = 90/235 (38%), Positives = 121/235 (51%), Gaps = 14/235 (5%) Query: 34 IIGGHEVTPHSRPYMASVRF---GGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGA 90 IIGGHE PHSRPYMA V+F + CGG L+R +V++AAHC + V LGA Sbjct: 1 IIGGHEAKPHSRPYMAFVQFLQEKSRKRCGGILVRKDFVLTAAHC----QGSSINVTLGA 56 Query: 91 HVLSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARP 150 H + E TQQ + HP Y+P +N+I LL+L A AV LR P +A+ Sbjct: 57 HNIKEQERTQQFIPVKRPIPHPAYNPKNFSNNIMLLQLERKAKWTTAVRPLRLPSSKAQ- 115 Query: 151 PTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWKGHLT-LTMLCTRSGDSH 209 G C VAGWG+VS L L E + V C + G+ + T +C Sbjct: 116 VKPGQLCSVAGWGYVS-MSTLATTLQEVLLTVQKDCQCERLFHGNYSRATEICVGDPKKT 174 Query: 210 RRGFCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVRR 264 + GF DSGGPLVC++ A G++S+ P VY +VS F+ WI ++R Sbjct: 175 QTGF-KGDSGGPLVCKDVAQGILSYGNK---KGTPPGVYIKVSHFLPWIKRTMKR 225 >2OQ5-A nrPDB Length = 232 Score = 258 bits (660), Expect = 2e-69, Method: Composition-based stats. Identities = 73/235 (31%), Positives = 110/235 (46%), Gaps = 15/235 (6%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCF-SHRDLRTGLVVLGAHV 92 I+GG EV P+ AS+++ G H CG L+ A W+VSAAHCF ++++ G Sbjct: 1 IVGGTEVEEGEWPWQASLQWDGSHRCGATLINATWLVSAAHCFTTYKNPARWTASFGV-- 58 Query: 93 LSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARPPT 152 T +P++ G+ + H Y +H DI L L+ AV + P + Sbjct: 59 --TIKPSKMKRGLRRIIVHEKYKHPSHDYDISLAELSSPVPYTNAVHRVCLPD-ASYEFQ 115 Query: 153 AGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCN--SSWKGHLTLTMLCTRSGDSHR 210 G V G+G + + L +A+V ++D CN ++ +T MLC S + + Sbjct: 116 PGDVMFVTGFGALKNDGYSQNHLRQAQVTLIDATTCNEPQAYNDAITPRMLCAGSLEG-K 174 Query: 211 RGFCSADSGGPLVCRN-----RAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWD 260 C DSGGPLV + G+VS+ G C P P VYT+V+A WI Sbjct: 175 TDACQGDSGGPLVSSDARDIWYLAGIVSW-GDECAKPNKPGVYTRVTALRDWITS 228 >1MZD-A nrPDB Length = 240 Score = 258 bits (659), Expect = 2e-69, Method: Composition-based stats. Identities = 85/237 (35%), Positives = 123/237 (51%), Gaps = 11/237 (4%) Query: 33 QIIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHC-FSHRDLRTGLVVLGAH 91 +IIGG EV+PHSRP+MAS+++GG H CGG L+ +WV++AAHC + ++ VVLGAH Sbjct: 2 EIIGGKEVSPHSRPFMASIQYGGHHVCGGVLIDPQWVLTAAHCQYRFTKGQSPTVVLGAH 61 Query: 92 VLSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARPP 151 LS E ++Q I +NDI L++L +A L V +L R Sbjct: 62 SLSKNEASKQTLEIKKFIPFSRVTSDPQSNDIMLVKLQTAAKLNKHVKMLH--IRSKTSL 119 Query: 152 TAGTRCRVAGWGFVSDFE-ELPPGLMEAKVRVLDPDVCNSS--WKG--HLTLTMLCTRSG 206 +GT+C+V GWG L E V VL +CNS + G +T M+C Sbjct: 120 RSGTKCKVTGWGATDPDSLRPSDTLREVTVTVLSRKLCNSQSYYNGDPFITKDMVCAGDA 179 Query: 207 DSHRRGFCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVS-AFVAWIWDVV 262 ++ C D+GGPL+C+ H +VS G CG P +YT ++ + WI + Sbjct: 180 -KGQKDSCKGDAGGPLICKGVFHAIVS-GGHECGVATKPGIYTLLTKKYQTWIKSNL 234 >1FIW-A nrPDB Length = 290 Score = 257 bits (657), Expect = 4e-69, Method: Composition-based stats. Identities = 80/273 (29%), Positives = 128/273 (46%), Gaps = 25/273 (9%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQH------HCGGFLLRARWVVSAAHCFS-HRDLRTGLV 86 IIGG + + P+M S++ H CGG LL ++W+++AAHCF + + + Sbjct: 1 IIGGQDAAHGAWPWMVSLQIFTYHNNRRYHVCGGSLLNSQWLLTAAHCFRIKKKVTDWRL 60 Query: 87 VLGAHVLST-----AEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLL 141 + GA + +P Q ++ + H Y + ANDI L+++ G +G Sbjct: 61 IFGAKEVEWGTNKPVKPPLQERYVEKIIIHEKYSASSEANDIALMKITPPVTCGHFIGPG 120 Query: 142 RPPGRRARPPTAGTRCRVAGWGFVSDF-EELPPGLMEAKVRVLDPDVCNS--SWKGHLTL 198 P RA PP C VAGWGF+ + P L EA+V ++D +CNS + G + Sbjct: 121 CLPQFRAGPPRVPQTCWVAGWGFLQENARRTSPMLQEARVDLIDLGLCNSTRWYNGRIRS 180 Query: 199 TMLCTRSGDSHRRGFCSADSGGPLVCRN------RAHGLVSFSGLWCGDPKTPDVYTQVS 252 T +C + + C DSGGPL+C++ G+ S+ G+ C K P VYT Sbjct: 181 TNVCAGYPEG-KIDTCQGDSGGPLMCKDSAENSYVVVGITSW-GVGCARAKRPGVYTSTW 238 Query: 253 AFVAWIWDVVRRSSPQPGPLPGTT--RPPGEAA 283 +++ WI + ++ LP + PG A Sbjct: 239 SYLNWIASKIGSTAVHMIQLPTASPASTPGAQA 271 >1ELT-A nrPDB Length = 236 Score = 257 bits (657), Expect = 4e-69, Method: Composition-based stats. Identities = 81/242 (33%), Positives = 118/242 (48%), Gaps = 19/242 (7%) Query: 34 IIGGHEVTPHSRPYMASVRFGG----QHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLG 89 ++GG P+S P+ S+++ H CGG L+R WV++AAHC RT VVLG Sbjct: 1 VVGGRVAQPNSWPWQISLQYKSGSSYYHTCGGSLIRQGWVMTAAHCVDS--ARTWRVVLG 58 Query: 90 AHVLSTAEPTQQVFGIDALTTHPDYHPMTH--ANDICLLRLNGSAVLGPAVGLLRPPGRR 147 H L+T E +Q+ ++++ H ++ DI LLRLN A L AV L P Sbjct: 59 EHNLNTNEGKEQIMTVNSVFIHSGWNSDDVAGGYDIALLRLNTQASLNSAVQLAALPPSN 118 Query: 148 ARPPTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNS--SWKGHLTLTMLCTRS 205 P C + GWG S L L +A + +D C+S W + TM+C Sbjct: 119 QILPN-NNPCYITGWGKTSTGGPLSDSLKQAWLPSVDHATCSSSGWWGSTVKTTMVCAG- 176 Query: 206 GDSHRRGFCSADSGGPLVCR----NRAHGLVSF-SGLWCGDPKTPDVYTQVSAFVAWIWD 260 C+ DSGGPL C+ HG+ SF S C K P V+T+VSA+++W+ Sbjct: 177 --GGANSGCNGDSGGPLNCQVNGSYYVHGVTSFVSSSGCNASKKPTVFTRVSAYISWMNG 234 Query: 261 VV 262 ++ Sbjct: 235 IM 236 >1Q3X-A nrPDB Length = 328 Score = 256 bits (654), Expect = 8e-69, Method: Composition-based stats. Identities = 67/268 (25%), Positives = 108/268 (40%), Gaps = 23/268 (8%) Query: 14 TVATALMLPVKPP-----AGSWGAQIIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARW 68 + LPV P A + G +I GG + P P+ + G G LL W Sbjct: 62 SSKGEKSLPVCEPVCGLSARTTGGRIYGGQKAKPGDFPWQVLIL--GGTTAAGALLYDNW 119 Query: 69 VVSAAHCFSHRDLRTGLVVLGAHVLSTAEPTQQVFGIDALTTHPDY-HPMTHANDICLLR 127 V++AAH + + + L P +A+ H Y H NDI L++ Sbjct: 120 VLTAAHAVYEQKHDASALDIRMGTLKRLSPHYTQAWSEAVFIHEGYTHDAGFDNDIALIK 179 Query: 128 LNGSAVLGPAVGLLRPPGRRARPP-TAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPD 186 LN V+ + + P + A +GWG L LM + ++D Sbjct: 180 LNNKVVINSNITPICLPRKEAESFMRTDDIGTASGWGLTQ-RGFLARNLMYVDIPIVDHQ 238 Query: 187 VCNSSW------KGHLTLTMLCTRSGDSHRRGFCSADSGGPLVCRNRAH------GLVSF 234 C +++ +G +T MLC +S + C DSGG LV + G+VS+ Sbjct: 239 KCTAAYEKPPYPRGSVTANMLCAG-LESGGKDSCRGDSGGALVFLDSETERWFVGGIVSW 297 Query: 235 SGLWCGDPKTPDVYTQVSAFVAWIWDVV 262 + CG+ VYT+V ++ WI +++ Sbjct: 298 GSMNCGEAGQYGVYTKVINYIPWIENII 325 >1A5I-A nrPDB Length = 265 Score = 255 bits (653), Expect = 1e-68, Method: Composition-based stats. Identities = 78/276 (28%), Positives = 113/276 (40%), Gaps = 32/276 (11%) Query: 4 GLRGWGRPLLTVATALMLPVKPPAGSWGAQIIGGHEVTPHSRPYMASVRFGGQHHCGGFL 63 GLR + P L L + + W A I + + + CGG L Sbjct: 3 GLRKYKEPQLHSTGGLFTDI--TSHPWQAAIFAQNRRSSGE-----------RFLCGGIL 49 Query: 64 LRARWVVSAAHCFSHRDLRTGL-VVLGAHVLSTAEPTQQVFGIDALTTHPDYHPMTHAND 122 + + WV++AAHCF L L VVLG +Q F + H ++ T+ ND Sbjct: 50 ISSCWVLTAAHCFQESYLPDQLKVVLGRTYRVKPGEEEQTFKVKKYIVHKEFDDDTYNND 109 Query: 123 ICLLRLNGS----AVLGPAVGLLRPPGRRARPPTAGTRCRVAGWGFVSDFEE-LPPGLME 177 I LL+L A +V + P + P T C ++G+G L E Sbjct: 110 IALLQLKSDSPQCAQESDSVRAICLPEANLQLPD-WTECELSGYGKHKSSSPFYSEQLKE 168 Query: 178 AKVRVLDPDVCNSS--WKGHLTLTMLCTRSGDSHR-----RGFCSADSGGPLVCRNRAH- 229 VR+ C + +T MLC S C DSGGPLVC N H Sbjct: 169 GHVRLYPSSRCAPKFLFNKTVTNNMLCAGDTRSGEIYPNVHDACQGDSGGPLVCMNDNHM 228 Query: 230 ---GLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVV 262 G++S+ G+ CG+ P VYT+V+ ++ WI D + Sbjct: 229 TLLGIISW-GVGCGEKDVPGVYTKVTNYLGWIRDNM 263 >1YC0-A nrPDB Length = 283 Score = 255 bits (651), Expect = 2e-68, Method: Composition-based stats. Identities = 82/244 (33%), Positives = 117/244 (47%), Gaps = 17/244 (6%) Query: 33 QIIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGL-VVLGAH 91 +IIGG P S P++A++ G C G L+ WVVSAAHCFSH R + VVLG H Sbjct: 35 RIIGGSSSLPGSHPWLAAIYIGDS-FCAGSLVHTCWVVSAAHCFSHSPPRDSVSVVLGQH 93 Query: 92 VLSTAEPTQQVFGIDALTTHPDYHPMT-HANDICLLRLNGS----AVLGPAVGLLRPPGR 146 + Q FGI+ + Y +D+ L+RL A V + P Sbjct: 94 FFNRTTDVTQTFGIEKYIPYTLYSVFNPSDHDLVLIRLKKKGDRCATRSQFVQPICLPEP 153 Query: 147 RARPPTAGTRCRVAGWGFVSDF-EELPPGLMEAKVRVLDPDVCNS--SWKGHLTLTMLCT 203 + P AG +C++AGWG + + L EA V ++ C+S + ++ MLC Sbjct: 154 GSTFP-AGHKCQIAGWGHLDENVSGYSSSLREALVPLVADHKCSSPEVYGADISPNMLCA 212 Query: 204 RSGDSHRRGFCSADSGGPLVCRNR----AHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIW 259 D + C DSGGPL C +G++S+ G CG P VYT+V+ +V WI Sbjct: 213 GYFDC-KSDACQGDSGGPLACEKNGVAYLYGIISW-GDGCGRLHKPGVYTRVANYVDWIN 270 Query: 260 DVVR 263 D +R Sbjct: 271 DRIR 274 >1ZJK-A nrPDB Length = 403 Score = 253 bits (647), Expect = 5e-68, Method: Composition-based stats. Identities = 68/268 (25%), Positives = 108/268 (40%), Gaps = 23/268 (8%) Query: 14 TVATALMLPVKPP-----AGSWGAQIIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARW 68 + LPV P A + G QI GG + P P+ + G G LL W Sbjct: 137 SSKGEKSLPVCEPVCGLSARTTGGQIYGGQKAKPGDFPWQVLIL--GGTTAAGALLYDNW 194 Query: 69 VVSAAHCFSHRDLRTGLVVLGAHVLSTAEPTQQVFGIDALTTHPDY-HPMTHANDICLLR 127 V++AAH + + + L P +A+ H Y H NDI L++ Sbjct: 195 VLTAAHAVYEQKHDASALDIRMGTLKRLSPHYTQAWSEAVFIHEGYTHDAGFDNDIALIK 254 Query: 128 LNGSAVLGPAVGLLRPPGRRARPP-TAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPD 186 LN V+ + + P + A +GWG L LM + ++D Sbjct: 255 LNNKVVINSNITPICLPRKEAESFMRTDDIGTASGWGLTQ-RGFLARNLMYVDIPIVDHQ 313 Query: 187 VCNSSW------KGHLTLTMLCTRSGDSHRRGFCSADSGGPLVCRNRAH------GLVSF 234 C +++ +G +T MLC +S + C DSGG LV + G+VS+ Sbjct: 314 KCTAAYEKPPYPRGSVTANMLCAG-LESGGKDSCRGDSGGALVFLDSETERWFVGGIVSW 372 Query: 235 SGLWCGDPKTPDVYTQVSAFVAWIWDVV 262 + CG+ VYT+V ++ WI +++ Sbjct: 373 GSMNCGEAGQYGVYTKVINYIPWIENII 400 >3S9B-A nrPDB Length = 234 Score = 252 bits (645), Expect = 1e-67, Method: Composition-based stats. Identities = 62/242 (25%), Positives = 95/242 (39%), Gaps = 13/242 (5%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQH--HCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAH 91 ++GG E + P++ ++ HC G L+ WV++AAHC D R + LG H Sbjct: 1 VVGGDECNINEHPFLVALYTSASSTIHCAGALINREWVLTAAHC----DRRNIRIKLGMH 56 Query: 92 VLSTAEPTQQVFGID-ALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARP 150 + +Q+ P DI L+RL + + P R Sbjct: 57 SKNIRNEDEQIRVPRGKYFCLNTKFPNGLDKDIMLIRLRRPVTYSTHIAPVSLPSRSRG- 115 Query: 151 PTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWKGHLTLT-MLCTRSGDSH 209 G+RCR+ GWG +S P + ++ C + + LC Sbjct: 116 --VGSRCRIMGWGKISTT-TYPDVPHCTNIFIVKHKWCEPLYPWVPADSRTLCAGILKGG 172 Query: 210 RRGFCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVRRSSPQP 269 R C DSGGPL+C HG+V+ CG P VYT+V + WI ++ + Sbjct: 173 R-DTCHGDSGGPLICNGEMHGIVAGGSEPCGQHLKPAVYTKVFDYNNWIQSIIAGNRTVT 231 Query: 270 GP 271 P Sbjct: 232 CP 233 >2XXL-A nrPDB Length = 408 Score = 252 bits (643), Expect = 1e-67, Method: Composition-based stats. Identities = 75/282 (26%), Positives = 116/282 (41%), Gaps = 42/282 (14%) Query: 32 AQIIGGHEVTPHSRPYMASVRFG----GQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVV 87 ++ G+EV SRP+MA +R+ + CGG ++ R++++AAHC + Sbjct: 117 QRVSNGYEVKLSSRPWMALLRYQQFGESRFLCGGAMISERYILTAAHCVHGLQNDLYEIR 176 Query: 88 LGAHVLSTAEPTQQV------------FGIDALTTHPDYHPMTHANDICLLRLNGSAVLG 135 LG H +ST E +Q GI+ H Y +DI LL+LN S Sbjct: 177 LGEHRISTEEDCRQQGRKKKCAPPVVNVGIEKHLIHEKYDARHIMHDIALLKLNRSVPFQ 236 Query: 136 PAVGLLRPPGRRARPPTAG--TRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWK 193 + + P A + V GWG ++ L++A V + C+ +++ Sbjct: 237 KHIKPICLPITDELKEKAEQISTYFVTGWG-TTENGSSSDVLLQANVPLQPRSACSQAYR 295 Query: 194 GHLTLTMLCTRSGDSHRRGFCSADSGGPLVC----------RNRAHGLVSFSGLWCGDPK 243 + L+ LC GD + C DSGGPL + G+VS + CG Sbjct: 296 RAVPLSQLCVGGGD--LQDSCKGDSGGPLQAPAQYLGEYAPKMVEFGIVSQGVVTCGQIS 353 Query: 244 TPDVYTQVSAFVAWIWDVVRRS-----------SPQPGPLPG 274 P +YT V +V WI D + + P P PL G Sbjct: 354 LPGLYTNVGEYVQWITDTMASNGLLESRGPFEGKPIPNPLLG 395 >2R0L-A nrPDB Length = 248 Score = 251 bits (642), Expect = 2e-67, Method: Composition-based stats. Identities = 82/243 (33%), Positives = 116/243 (47%), Gaps = 17/243 (6%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGL-VVLGAHV 92 IIGG P S P++A++ G C G L+ WVVSAAHCFSH R + VVLG H Sbjct: 1 IIGGSSSLPGSHPWLAAIYIGDS-FCAGSLVHTCWVVSAAHCFSHSPPRDSVSVVLGQHF 59 Query: 93 LSTAEPTQQVFGIDALTTHPDYHPMT-HANDICLLRLNGS----AVLGPAVGLLRPPGRR 147 + Q FGI+ + Y +D+ L+RL A V + P Sbjct: 60 FNRTTDVTQTFGIEKYIPYTLYSVFNPSDHDLVLIRLKKKGDRCATRSQFVQPICLPEPG 119 Query: 148 ARPPTAGTRCRVAGWGFVSDF-EELPPGLMEAKVRVLDPDVCNS--SWKGHLTLTMLCTR 204 + P AG +C++AGWG + + L EA V ++ C+S + ++ MLC Sbjct: 120 STFP-AGHKCQIAGWGHLDENVSGYSSSLREALVPLVADHKCSSPEVYGADISPNMLCAG 178 Query: 205 SGDSHRRGFCSADSGGPLVCRNR----AHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWD 260 D + C DSGGPL C +G++S+ G CG P VYT+V+ +V WI D Sbjct: 179 YFDC-KSDACQGDSGGPLACEKNGVAYLYGIISW-GDGCGRLHKPGVYTRVANYVDWIND 236 Query: 261 VVR 263 +R Sbjct: 237 RIR 239 >3RP2-A nrPDB Length = 224 Score = 250 bits (640), Expect = 3e-67, Method: Composition-based stats. Identities = 82/234 (35%), Positives = 119/234 (50%), Gaps = 14/234 (5%) Query: 34 IIGGHEVTPHSRPYMASVRF----GGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLG 89 IIGG E PHSRPYMA + G + CGGFL+ ++V++AAHC R V+LG Sbjct: 1 IIGGVESIPHSRPYMAHLDIVTEKGLRVICGGFLISRQFVLTAAHC----KGREITVILG 56 Query: 90 AHVLSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRAR 149 AH + E TQQ ++ H Y+ + + +DI LL+L L PAV ++ P + Sbjct: 57 AHDVRKRESTQQKIKVEKQIIHESYNSVPNLHDIMLLKLEKKVELTPAVNVVPLPS-PSD 115 Query: 150 PPTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWKGHLTLTMLCTRSGDSH 209 G C AGWG + L E ++R++D C ++ + +C S + Sbjct: 116 FIHPGAMCWAAGWGKTGVRDPTSYTLREVELRIMDEKAC-VDYRYYEYKFQVCVGSPTTL 174 Query: 210 RRGFCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVR 263 R DSGGPL+C AHG+VS+ D K P ++T+VS +V WI V+ Sbjct: 175 R-AAFMGDSGGPLLCAGVAHGIVSYGHP---DAKPPAIFTRVSTYVPWINAVIN 224 >4XDE-A nrPDB Length = 257 Score = 250 bits (639), Expect = 5e-67, Method: Composition-based stats. Identities = 77/243 (31%), Positives = 116/243 (47%), Gaps = 20/243 (8%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRD-LRTGLVVLGAHV 92 ++GG + PY+A++ + G C G L+ WV++AAHC R VVLG Sbjct: 3 VVGGLVALRGAHPYIAALYW-GHSFCAGSLIAPCWVLTAAHCLQDRPAPEDLTVVLGQER 61 Query: 93 LSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAV-----LGPAVGLLRPPGRR 147 + + Q + + H + P+++ +D+ LLRL A L P V + P Sbjct: 62 RNHSCEPCQTLAVRSYRLHEAFSPVSYQHDLALLRLQEDADGSCALLSPYVQPVSLPSGA 121 Query: 148 ARPPTAGTRCRVAGWGFVSDF-EELPPGLMEAKVRVLDPDVCNS--SWKGHLTLTMLCTR 204 AR P+ T C+VAGWG + EE L EA+V L + C++ + MLC Sbjct: 122 AR-PSETTLCQVAGWGHQFEGAEEYASFLQEAQVPFLSLERCSAPDVHGSSILPGMLCAG 180 Query: 205 SGDSHRRGFCSADSGGPLVCRNR-------AHGLVSFSGLWCGDPKTPDVYTQVSAFVAW 257 + C DSGGPLVC ++ G++S+ G CGD P VYT V+ ++AW Sbjct: 181 FLEGG-TDACQGDSGGPLVCEDQAAERRLTLQGIISW-GSGCGDRNKPGVYTDVAYYLAW 238 Query: 258 IWD 260 I + Sbjct: 239 IRE 241 >2ZKS-A nrPDB Length = 240 Score = 250 bits (638), Expect = 6e-67, Method: Composition-based stats. Identities = 99/238 (41%), Positives = 131/238 (55%), Gaps = 11/238 (4%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVL 93 IIGG EV PHSRPYMAS++ G H CGG L+ +WV++AAHC + R + +VLG H L Sbjct: 1 IIGGREVIPHSRPYMASLQRNGSHLCGGVLVHPKWVLTAAHCLAQRMAQL-RLVLGLHTL 59 Query: 94 STAEPTQQVFGIDALTTHPDYHP-MTHANDICLLRLNGSAVLGPAVGLLRPPGRRARPPT 152 + F I A HP Y P ND+ LL+L+G + L P +R + Sbjct: 60 ---DSPGLTFHIKAAIQHPRYKPVPALENDLALLQLDGKVKPSRTIRPLALPSKR-QVVA 115 Query: 153 AGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSS--WKGHLTLTMLCTRSGDSHR 210 AGTRC +AGWG L L E ++VLD +CN+S W G L+ +M+C + DS Sbjct: 116 AGTRCSMAGWGLTHQGGRLSRVLRELDLQVLDTRMCNNSRFWNGSLSPSMVCLAA-DSKD 174 Query: 211 RGFCSADSGGPLVCRN--RAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVRRSS 266 + C DSGGPLVC G++SFS C D P V T V+ +V+WI V RS+ Sbjct: 175 QAPCKGDSGGPLVCGKGRVLAGVLSFSSRVCTDIFKPPVATAVAPYVSWIRKVTGRSA 232 >5TO3-B nrPDB Length = 409 Score = 249 bits (637), Expect = 9e-67, Method: Composition-based stats. Identities = 61/257 (23%), Positives = 99/257 (38%), Gaps = 27/257 (10%) Query: 34 IIGGHEVTPHSRPYMASVRFGG--QHHCGGFLLRARWVVSAAHCFSHRDL------RTGL 85 I+ G + P+ + + CG L+ RWV++AAHC + L Sbjct: 1 IVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLL 60 Query: 86 VVLGAHVLSTAEPT-QQVFGIDALTTHPDYHP-MTHANDICLLRLNGSAVLGPAVGLLRP 143 V +G H + E +++ ++ + HP Y+ DI L++L + + Sbjct: 61 VRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCL 120 Query: 144 PGRRA--RPPTAGTRCRVAGWGFVSD------FEELPPGLMEAKVRVLDPDVCNSSWKGH 195 P R AG + RV GWG + + + P L + +++ VC S + Sbjct: 121 PDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDSTRIR 180 Query: 196 LTLTMLCTRSG--DSHRRGFCSADSGGPLVCR------NRAHGLVSFSGLWCGDPKTPDV 247 +T M C + R C DSGGP V + G+VS +G C Sbjct: 181 ITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVS-AGAGCDRDGKYGF 239 Query: 248 YTQVSAFVAWIWDVVRR 264 YT V WI V+ + Sbjct: 240 YTHVFRLKKWIQKVIDQ 256 >1AZZ-A nrPDB Length = 226 Score = 249 bits (636), Expect = 1e-66, Method: Composition-based stats. Identities = 69/227 (30%), Positives = 106/227 (46%), Gaps = 9/227 (3%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVL 93 I+GG E P+S P+ A++ + CGG L+ W+++AAHC VVLGAH + Sbjct: 1 IVGGVEAVPNSWPHQAALFIDDMYFCGGSLISPEWILTAAHCMDGAGFVD--VVLGAHNI 58 Query: 94 STAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARPPTA 153 E TQ T H +Y+ +NDI ++RL L A+ + P Sbjct: 59 REDEATQVTIQSTDFTVHENYNSFVISNDIAVIRLPVPVTLTAAIATVGLPSTD---VGV 115 Query: 154 GTRCRVAGWGFVSDFE-ELPPGLMEAKVRVLDPDVCNSSWKGHLTLTMLCTRSGDSHRRG 212 GT GWG SD + L + V ++ C++ + G +T +C S + +G Sbjct: 116 GTVVTPTGWGLPSDSALGISDVLRQVDVPIMSNADCDAVY-GIVTDGNICIDS--TGGKG 172 Query: 213 FCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIW 259 C+ DSGGPL +G+ SF + PD +T+V+ F+ WI Sbjct: 173 TCNGDSGGPLNYNGLTYGITSFGAAAGCEAGYPDAFTRVTYFLDWIQ 219 >3F6U-H nrPDB Length = 240 Score = 249 bits (636), Expect = 1e-66, Method: Composition-based stats. Identities = 70/242 (28%), Positives = 97/242 (40%), Gaps = 17/242 (7%) Query: 35 IGGHEVTPHSRPYMASVRFGGQHH-CGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVL 93 I G P+ + + CG L+ WV++AAHC LV LG + L Sbjct: 2 IDGKMTRRGDSPWQVVLLDSKKKLACGAVLIHPSWVLTAAHCMDESKK--LLVRLGEYDL 59 Query: 94 STAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGR---RARP 150 E + I + HP+Y T NDI LL L A L + + P Sbjct: 60 RRWEKWELDLDIKEVFVHPNYSKSTTDNDIALLHLAQPATLSQTIVPICLPDSGLAEREL 119 Query: 151 PTAGTRCRVAGWGFVSDFEELPP-----GLMEAKVRVLDPDVCNSSWKGHLTLTMLCTRS 205 AG V GWG+ S E+ L K+ V+ + C+ ++ MLC Sbjct: 120 NQAGQETLVTGWGYHSSREKEAKRNRTFVLNFIKIPVVPHNECSEVMSNMVSENMLCAGI 179 Query: 206 GDSHRRGFCSADSGGPLVCRNRAH----GLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDV 261 R+ C DSGGP+V GLVS+ G CG VYT+VS ++ WI Sbjct: 180 L-GDRQDACEGDSGGPMVASFHGTWFLVGLVSW-GEGCGLLHNYGVYTKVSRYLDWIHGH 237 Query: 262 VR 263 +R Sbjct: 238 IR 239 >4FXG-H nrPDB Length = 242 Score = 248 bits (633), Expect = 2e-66, Method: Composition-based stats. Identities = 60/243 (24%), Positives = 99/243 (40%), Gaps = 18/243 (7%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVL 93 I GG + P P+ + G G LL WV++AAH + + + L Sbjct: 1 IYGGQKAKPGDFPWQVLIL--GGTTAAGALLYDNWVLTAAHAVYEQKHDASALDIRMGTL 58 Query: 94 STAEPTQQVFGIDALTTHPDY-HPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARPP- 151 P +A+ H Y H NDI L++LN V+ + + P + A Sbjct: 59 KRLSPHYTQAWSEAVFIHEGYTHDAGFDNDIALIKLNNKVVINSNITPICLPRKEAESFM 118 Query: 152 TAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSW------KGHLTLTMLCTRS 205 +GWG L LM + ++D C +++ +G +T MLC Sbjct: 119 RTDDIGTASGWGLTQ-RGFLARNLMYVDIPIVDHQKCTAAYEKPPYPRGSVTANMLCAG- 176 Query: 206 GDSHRRGFCSADSGGPLVCRNRAH------GLVSFSGLWCGDPKTPDVYTQVSAFVAWIW 259 +S + C D+GG LV + G+VS+ + CG+ VYT+V ++ WI Sbjct: 177 LESGGKDSCRGDAGGALVFLDSETERWFVGGIVSWGSMNCGEAGQYGVYTKVINYIPWIE 236 Query: 260 DVV 262 +++ Sbjct: 237 NII 239 >1KYN-A nrPDB Length = 235 Score = 247 bits (631), Expect = 4e-66, Method: Composition-based stats. Identities = 90/234 (38%), Positives = 117/234 (50%), Gaps = 13/234 (5%) Query: 34 IIGGHEVTPHSRPYMASVRFG---GQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGA 90 IIGG E PHSRPYMA ++ GQ CGGFL+R +V++AAHC+ V LGA Sbjct: 1 IIGGRESRPHSRPYMAYLQIQSPAGQSRCGGFLVREDFVLTAAHCWGS----NINVTLGA 56 Query: 91 HVLSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARP 150 H + E TQQ HP Y+ T NDI LL+L+ V + P R Sbjct: 57 HNIQRRENTQQHITARRAIRHPQYNQRTIQNDIMLLQLSRRVRRNRNVNPVALP-RAQEG 115 Query: 151 PTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWKGHLTLTMLCTRSGDSHR 210 GT C VAGWG VS L E ++RV C + + +C R Sbjct: 116 LRPGTLCTVAGWGRVS-MRRGTDTLREVQLRVQRDRQCLRIFGSYDPRRQICVGDRRE-R 173 Query: 211 RGFCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVRR 264 + DSGGPL+C N AHG+VS+ G G P P+V+T+VS+F+ WI +R Sbjct: 174 KAAFKGDSGGPLLCNNVAHGIVSY-GKSSGVP--PEVFTRVSSFLPWIRTTMRS 224 >5LPF-A nrPDB Length = 234 Score = 246 bits (628), Expect = 8e-66, Method: Composition-based stats. Identities = 75/238 (31%), Positives = 112/238 (47%), Gaps = 19/238 (7%) Query: 37 GHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVLSTA 96 G S+P+ S+ G HC G L+ WV++AAHC + +G L Sbjct: 7 GSPCARGSQPWQVSLFNGLSFHCAGVLVDQSWVLTAAHC----GNKPLWARVGDDHLLLL 62 Query: 97 EPTQQVFGIDALTTHPDYHP--------MTHANDICLLRLNGSAVLGPAVGLLRPPGRRA 148 +Q+ HP YH T +D+ LL+L VLGP V L+ P R A Sbjct: 63 -QGEQLRRTTRSVVHPKYHQGSGPILPRRTDEHDLMLLKLARPVVLGPRVRALQLPYRCA 121 Query: 149 RPPTAGTRCRVAGWGFVSDFE-ELPPGLMEAKVRVLDPDVCNSSWKGHLTLTMLCTRSGD 207 +P G +C+VAGWG + + GL + + +L P C + G +T M+C Sbjct: 122 QP---GDQCQVAGWGTTAARRVKYNKGLTCSSITILSPKECEVFYPGVVTNNMICAG--L 176 Query: 208 SHRRGFCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVRRS 265 + C +DSGGPLVC G++S+ CG + P VYTQ+ +++WI V+R + Sbjct: 177 DRGQDPCQSDSGGPLVCDETLQGILSWGVYPCGSAQHPAVYTQICKYMSWINKVIRSN 234 >1SC8-U nrPDB Length = 262 Score = 245 bits (626), Expect = 2e-65, Method: Composition-based stats. Identities = 74/251 (29%), Positives = 110/251 (43%), Gaps = 22/251 (8%) Query: 33 QIIGGHEVTPHSRPYMASVRFGGQ-----HHCGGFLLRARWVVSAAHCF-SHRDLRTGLV 86 +IIGG T ++P+ A++ + + CGG L+ WV+SA HCF + +V Sbjct: 15 KIIGGEFTTIENQPWFAAIYRRHRGGSVTYVCGGSLISPCWVISATHCFIDYPKKEDYIV 74 Query: 87 VLGAHVLSTAEPTQQVFGIDALTTHPDYHPMT--HANDICLLRLNGS----AVLGPAVGL 140 LG L++ + F ++ L H DY T H NDI LL++ A + Sbjct: 75 YLGRSRLNSNTQGEMKFEVENLILHKDYSADTLAHHNDIALLKIRSKEGRCAQPSRTIQT 134 Query: 141 LRPPGRRARPPTAGTRCRVAGWGFVSDFEE-LPPGLMEAKVRVLDPDVCNS--SWKGHLT 197 + P P GT C + G+G + + P L V+++ C + +T Sbjct: 135 ISLPSMY-NDPQFGTSCEITGFGKENSTDYLYPEQLKMTVVKLISHRECQQPHYYGSEVT 193 Query: 198 LTMLCTRSGDSHRRGFCSADSGGPLVC----RNRAHGLVSFSGLWCGDPKTPDVYTQVSA 253 MLC + C DSGGPLVC R G+VS+ G C P VYT+VS Sbjct: 194 TKMLCAADPQ-WKTDSCQGDSGGPLVCSLQGRMTLTGIVSW-GRGCALKDKPGVYTRVSH 251 Query: 254 FVAWIWDVVRR 264 F+ WI + Sbjct: 252 FLPWIRSHTKE 262 >5LHN-A nrPDB Length = 247 Score = 244 bits (623), Expect = 4e-65, Method: Composition-based stats. Identities = 70/249 (28%), Positives = 111/249 (44%), Gaps = 23/249 (9%) Query: 34 IIGGHEVTPHSRPYMASVRFGG------QHHCGGFLLRARWVVSAAHCFSHRDLR-TGLV 86 I+GG ++P+ A++ CGG L+ WV SAAHCF + +V Sbjct: 1 IVGGEFTEVENQPWFAAIYQKNKGGSPPSFKCGGSLISPCWVASAAHCFIQLPKKENYVV 60 Query: 87 VLGAHVLSTAEPTQQVFGIDALTTHPDY--HPMTHANDICLLRLNGS----AVLGPAVGL 140 LG S+ P + F ++ L H Y + + NDI LL++ S A ++ Sbjct: 61 YLGQSKESSYNPGEMKFEVEQLILHEYYREDSLAYHNDIALLKIRTSTGQCAQPSRSIQT 120 Query: 141 LRPPGRRARPPTAGTRCRVAGWGFVSDFEE-LPPGLMEAKVRVLDPDVCNS--SWKGHLT 197 + P R P G+ C + G+G S+ + P L + V+++ + C + + Sbjct: 121 IALPPRFTDAPF-GSDCEITGFGKESESDYLYPKNLKMSVVKLVSHEQCMQPHYYGSEIN 179 Query: 198 LTMLCTRSGDSHRRGFCSADSGGPLVCRNRAH----GLVSFSGLWCGDPKTPDVYTQVSA 253 MLC + + C DSGGPL+C G+VS+ G C + P VYT+VS Sbjct: 180 YKMLCAADPE-WKTDSCKGDSGGPLICNIEGRPTLSGIVSW-GRGCAEKNKPGVYTRVSH 237 Query: 254 FVAWIWDVV 262 F+ WI + Sbjct: 238 FLDWIQSHI 246 >2RDL-A nrPDB Length = 226 Score = 243 bits (622), Expect = 5e-65, Method: Composition-based stats. Identities = 84/236 (35%), Positives = 113/236 (47%), Gaps = 14/236 (5%) Query: 34 IIGGHEVTPHSRPYMASVRF--GGQHH--CGGFLLRARWVVSAAHCFSHRDLRTGLVVLG 89 IIGG E PH+RPYMA + H C GFL+R +V++AAHC R+ V+LG Sbjct: 1 IIGGTECRPHARPYMAYLEIVTPENHLSACSGFLIRRNFVMTAAHC----AGRSITVLLG 56 Query: 90 AHVLSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRAR 149 AH E T Q ++ HP Y NDI LL+L A L VG L P ++ Sbjct: 57 AHNKKVKEDTWQKLEVEKQFPHPKYDDRLVLNDIMLLKLKEKANLTLGVGTL-PISAKSN 115 Query: 150 PPTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWKGHLTLTMLCTRSGDSH 209 G CR GWG + E L E K+R+LDP C H LC + Sbjct: 116 SIPPGRVCRAVGWGRTNVNEPPSDTLQEVKMRILDPQACKHFEDFH-QEPQLCVGNPKKI 174 Query: 210 RRGFCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVRRS 265 R + DSGGPL+C A G+ S+ + K P V+T++S + WI ++R + Sbjct: 175 RNVY-KGDSGGPLLCAGIAQGIASYVLR---NAKPPSVFTRISHYRPWINKILREN 226 >1AE5-A nrPDB Length = 225 Score = 243 bits (621), Expect = 5e-65, Method: Composition-based stats. Identities = 88/239 (36%), Positives = 126/239 (52%), Gaps = 16/239 (6%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVL 93 I+GG + P P++AS++ G+H CGG L+ AR+V++AA CF ++ VVLGA+ L Sbjct: 1 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDL 60 Query: 94 STAE-PTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARPPT 152 E ++Q F I +++ + Y P + ND+ LL+L+ A L +V +L P + Sbjct: 61 RRRERQSRQTFSISSMSEN-GYDPQQNLNDLMLLQLDREANLTSSVTILPLP-LQNATVE 118 Query: 153 AGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWKGHLTLTMLCTRSGDSHRRG 212 AGTRC+VAGWG L V V D C +CT + R G Sbjct: 119 AGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCR--------PNNVCTGVL-TRRGG 169 Query: 213 FCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVRRSSPQPGP 271 C+ D G PLVC AHG+ SFS CG PD +T+V+ F WI V+ ++P PGP Sbjct: 170 ICNGDGGTPLVCEGLAHGVASFSLGPCGRG--PDFFTRVALFRDWIDGVL--NNPGPGP 224 >1FON-A nrPDB Length = 240 Score = 243 bits (620), Expect = 7e-65, Method: Composition-based stats. Identities = 82/246 (33%), Positives = 118/246 (47%), Gaps = 22/246 (8%) Query: 36 GGHEVTPHSRPYMASVRFGG----QHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAH 91 G + P+S + S+++ H CGG L+ WVV+A HC S RT VVLG + Sbjct: 1 NGEDAVPYSWSWQVSLQYEKDGAFHHTCGGSLIAPDWVVTAGHCISTS--RTYQVVLGEY 58 Query: 92 VLSTAEPTQQVFGIDA--LTTHPDYHPMTH--ANDICLLRLNGSAVLGPAVGLLRPPGRR 147 S E ++QV I+A L HP ++ NDI L++L+ SA LG V L P Sbjct: 59 DRSVLEGSEQVIPINAGDLFVHPLWNSNCVACGNDIALVKLSRSAQLGDKVQLANLPPAG 118 Query: 148 ARPPTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNS--SWKGHLTLTMLCTRS 205 P C ++GWG + LP L +A + +D + C+ W + TM+C Sbjct: 119 DILPNE-APCYISGWGRLYTGGPLPDKLQQALLPTVDYEHCSQWDWWGITVKKTMVCAG- 176 Query: 206 GDSHRRGFCSADSGGPLVC-----RNRAHGLVSFSGL-WCGDPKTPDVYTQVSAFVAWIW 259 R C+ DSGGPL C + HG+ SF C K P V+T+VSAF+ WI Sbjct: 177 --GDTRSGCNGDSGGPLNCPAADGSWQVHGVTSFVSAFGCNTIKKPTVFTRVSAFIDWID 234 Query: 260 DVVRRS 265 + + + Sbjct: 235 ETIASN 240 >1YM0-A nrPDB Length = 238 Score = 241 bits (616), Expect = 2e-64, Method: Composition-based stats. Identities = 65/242 (26%), Positives = 105/242 (43%), Gaps = 14/242 (5%) Query: 34 IIGGHEVTPHSRPYMASVRF--GGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAH 91 I+GG E P+ P+ SVR H CGG ++ RWVV AAHC +V+G H Sbjct: 1 IVGGIEARPYEFPWQVSVRRKSSDSHFCGGSIINDRWVVCAAHCMQGEAPALVSLVVGEH 60 Query: 92 VLSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARPP 151 S A +Q +D++ + +Y P T ND+ +++ + VG + P Sbjct: 61 DSSAASTVRQTHDVDSIFVNENYDPATLENDVSVIKTAVAITFDINVGPICAPDPANDYV 120 Query: 152 TAGTRCRVAGWGFVSDFEE-LPPGLMEAKVRVLDPDVCNSSWKG-HLTLTMLCTRSGDS- 208 ++C +GWG ++ P L + + C++ + + M+C Sbjct: 121 YRKSQC--SGWGTINSGGVCCPAVLRYVTLNITTNAFCDAVYTSDTIYDDMICATDNTGM 178 Query: 209 HRRGFCSADSGGPLVCRN-----RAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVR 263 R C DSGGPL ++ G+VS+ G+ C P VY++V WI D + Sbjct: 179 TDRDSCQGDSGGPLSVKDGSGIFSLVGIVSW-GIGCAS-GYPGVYSRVGFHAGWITDTIT 236 Query: 264 RS 265 + Sbjct: 237 NN 238 >4IW4-E nrPDB Length = 279 Score = 239 bits (610), Expect = 1e-63, Method: Composition-based stats. Identities = 73/283 (25%), Positives = 104/283 (36%), Gaps = 43/283 (15%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQH-------HCGGFLLRARWVVSAAHCFSHRDLRT--- 83 IIGG P P+ A + G LL A W+++AAH + T Sbjct: 1 IIGGRNAEPGLFPWQALIVVEDTSRVPNDKWFGSGALLSASWILTAAHVLRSQRRDTTVI 60 Query: 84 ------GLVVLGAHVLSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPA 137 V LG H + + HPD++ + +DI L++L LGP Sbjct: 61 PVSKEHVTVYLGLHDVRDKSGAVN-SSAARVVLHPDFNIQNYNHDIALVQLQEPVPLGPH 119 Query: 138 VGLLRPPGRRARPPTAGTRCRVAGWGFVSDF-----------EELPPGLMEAKVRVLDPD 186 V + P P VAGWG + L L K+ V+ Sbjct: 120 VMPVCLPRLEPEGPAPHMLGLVAGWGISNPNVTVDEIISSGTRTLSDVLQYVKLPVVPHA 179 Query: 187 VCNSSWKGH-----LTLTMLCTRSGDSHRRGFCSADSGGPLV------CRNRAHGLVSFS 235 C +S++ +T M C + + C DSGG V R GLVS+ Sbjct: 180 ECKTSYESRSGNYSVTENMFCAGYYEGGK-DTCLGDSGGAFVIFDDLSQRWVVQGLVSWG 238 Query: 236 G-LWCGDPKTPDVYTQVSAFVAWIWDVVRRSSPQPGPLPGTTR 277 G CG + VYT+VS +V W+W+ + PQ P R Sbjct: 239 GPEECGSKQVYGVYTKVSNYVDWVWEQMG--LPQSVVEPQVER 279 >1PPF-E nrPDB Length = 218 Score = 239 bits (610), Expect = 1e-63, Method: Composition-based stats. Identities = 82/230 (35%), Positives = 118/230 (51%), Gaps = 12/230 (5%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVL 93 I+GG PH+ P+M S++ G H CG L+ +V+SAAHC ++ ++R VVLGAH L Sbjct: 1 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNL 60 Query: 94 STAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARPPTA 153 S EPT+QVF + + + Y P+ NDI +L+LNGSA + V + + P + R Sbjct: 61 SRREPTRQVFAVQRIFEN-GYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRR-LGN 118 Query: 154 GTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWKGHLTLTMLCTRSGDSHRRGF 213 G +C GWG + + L E V V+ +C S +CT + G Sbjct: 119 GVQCLAMGWGLLGRNRGIASVLQELNVTVVT-SLCRRS--------NVCTLV-RGRQAGV 168 Query: 214 CSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVR 263 C DSG PLVC HG+ SF C PD + V+ FV WI +++ Sbjct: 169 CFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQ 218 >4KKD-A nrPDB Length = 433 Score = 238 bits (607), Expect = 3e-63, Method: Composition-based stats. Identities = 72/285 (25%), Positives = 104/285 (36%), Gaps = 43/285 (15%) Query: 32 AQIIGGHEVTPHSRPYMASVRFGGQH-------HCGGFLLRARWVVSAAHCFSHRDLRT- 83 +IIGG P P+ A + G LL A W+++AAH + T Sbjct: 153 QRIIGGRNAEPGLFPWQALIVVEDTSRVPNDKWFGSGALLSASWILTAAHVLRSQRRDTT 212 Query: 84 --------GLVVLGAHVLSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLG 135 V LG H + + HPD++ + +DI L++L LG Sbjct: 213 VIPVSKEHVTVYLGLHDVRDKSGAVN-SSAARVVLHPDFNIQNYNHDIALVQLQEPVPLG 271 Query: 136 PAVGLLRPPGRRARPPTAGTRCRVAGWGFVSDF-----------EELPPGLMEAKVRVLD 184 P V + P P VAGWG + L L K+ V+ Sbjct: 272 PHVMPVCLPRLEPEGPAPHMLGLVAGWGISNPNVTVDEIISSGTRTLSDVLQYVKLPVVP 331 Query: 185 PDVCNSSWKGH-----LTLTMLCTRSGDSHRRGFCSADSGGPLV------CRNRAHGLVS 233 C +S++ +T M C + + C DSG V R GLVS Sbjct: 332 HAECKTSYESRSGNYSVTENMFCAGYYEGGK-DTCLGDSGEAFVIFDDLSQRWVVQGLVS 390 Query: 234 FSG-LWCGDPKTPDVYTQVSAFVAWIWDVVRRSSPQPGPLPGTTR 277 + G CG + VYT+VS +V W+W+ + PQ P R Sbjct: 391 WGGPEECGSKQVYGVYTKVSNYVDWVWEQMG--LPQSVVEPQVER 433 >4BXW-A nrPDB Length = 423 Score = 237 bits (606), Expect = 3e-63, Method: Composition-based stats. Identities = 68/285 (23%), Positives = 107/285 (37%), Gaps = 21/285 (7%) Query: 6 RGWGRPLLTVATALMLPVKPPAGSWGAQIIGGHEVTPHSRPYMASVRFGGQH-HCGGFLL 64 R P + L K S +I+ G + P+ A++ + CGG +L Sbjct: 142 REANLPDFVQSQNATLLKKSDNPSPDIRIVNGMDCKLGECPWQAALVDEKEGVFCGGTIL 201 Query: 65 RARWVVSAAHCFSHRDLRTGLVVLGAHVLSTAEPTQQVFGIDALTTHPDYHPMT------ 118 +V++AAHC + T VV+G S E T + +D + H + P Sbjct: 202 SPIYVLTAAHCINET--ETISVVVGEIDKSRIE-TGPLLSVDKIYVHKKFVPPQKAYKFD 258 Query: 119 ---HANDICLLRLNGSAVLGPAVGLLRPPGRRARPPTAGTR--CRVAGWGFVSDFEELPP 173 + DI ++++ V P + V+G+G + + Sbjct: 259 LAAYDYDIAIIQMKTPIQFSENVVPACLPTADFANQVLMKQDFGIVSGFGRIVEKGPKSK 318 Query: 174 GLMEAKVRVLDPDVCNSSWKGHLTLTMLCTRSGDSHRRGFCSADSGGPLVCRNR----AH 229 L KV +D C S + +T M C D+ R C DSGGP R Sbjct: 319 TLKVLKVPYVDRHTCMVSSETPITPNMFCAGY-DTLPRDACQGDSGGPHTTVYRDTHFIT 377 Query: 230 GLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVRRSSPQPGPLPG 274 G+VS SG C YT++S F+ WI ++R+ P G Sbjct: 378 GIVS-SGEGCARNGKYGNYTKLSKFIPWIKRIMRQKLPSTESSTG 421 >4IGD-A nrPDB Length = 406 Score = 237 bits (606), Expect = 3e-63, Method: Composition-based stats. Identities = 79/282 (28%), Positives = 115/282 (40%), Gaps = 33/282 (11%) Query: 8 WGRPLLTVATALMLPVK---PPAGSWGAQIIGGHEVTPHSRPYMASV-RFGGQHHCGGFL 63 W +L + LPV + AQI G + P++A + GQ CGG L Sbjct: 127 WMNKVLGRSLPTCLPVCGLPKFSRKLMAQIFNGRPAQKGTTPWIAMLSHLNGQPFCGGSL 186 Query: 64 LRARWVVSAAHCFSHR--------------DLRTGLVVLGAHVLSTAEPTQQVFGIDALT 109 L + W+V+AAHC ++LG H ++ +Q G+ T Sbjct: 187 LGSSWIVTAAHCLHQSLDPEDPTLRDSDLLSPSDFKIILGKHWRLRSDENEQHLGVKHTT 246 Query: 110 THPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARPPTAGTRCRVAGWGFVSDFE 169 HP Y P T ND+ L+ L S VL V + P P G V+GWG + Sbjct: 247 LHPQYDPNTFENDVALVELLESPVLNAFVMPICLPE---GPQQEGAMVIVSGWGK-QFLQ 302 Query: 170 ELPPGLMEAKVRVLDPDVCNSSW---KGHLTLTMLCTRSGDSHRRGFCSADSGGPLVCRN 226 P LME ++ ++D C ++ K +T M+C + + C+ DSGGP+V N Sbjct: 303 RFPETLMEIEIPIVDHSTCQKAYAPLKKKVTRDMICAGEKEGGK-DACAGDSGGPMVTLN 361 Query: 227 R------AHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVV 262 R G VS+ CG VY+ + WI V Sbjct: 362 RERGQWYLVGTVSWGDD-CGKKDRYGVYSYIHHNKDWIQRVT 402 >5XRF-A nrPDB Length = 242 Score = 235 bits (600), Expect = 1e-62, Method: Composition-based stats. Identities = 67/243 (27%), Positives = 107/243 (44%), Gaps = 13/243 (5%) Query: 34 IIGGHEVTPHSRPYMASVRFG--GQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAH 91 +IGG+E + ++A+ C G L+ WV++AAHC+ R + LG H Sbjct: 7 VIGGNECDTNEHRFLAAFFTSRPWTFQCAGTLIHEEWVLAAAHCYK----RGLNIYLGMH 62 Query: 92 VLSTAEPTQQVF-GIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARP 150 S +Q I+ D D+ LL+LN + L + P Sbjct: 63 NQSIQFDDEQRRYAIEEHYYRCDEKLTKWEKDVVLLKLNKPVSNSTHIAPL---SLPSSP 119 Query: 151 PTAGTRCRVAGWGFVSDFEE-LPPGLMEAKVRVLDPDVCNSSWKGHL-TLTMLCTRSGDS 208 P+ G+ CRV GWG +S ++ LP A + +L+ C + + T +LC + Sbjct: 120 PSIGSVCRVMGWGIMSSTKDILPDVPHCANINLLNYMECVAHYPDVPETTRLLCAGVLEG 179 Query: 209 HRRGFCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVRRSSPQ 268 C+ DSGGPL+C + G+V F C P P +YT+VS + WI +++ + Sbjct: 180 GI-DTCNQDSGGPLICDGQFQGIVFFGKYPCAQPNKPGLYTRVSNYNDWIQNIIAGKTTT 238 Query: 269 PGP 271 P Sbjct: 239 ACP 241 >4DJZ-B nrPDB Length = 251 Score = 234 bits (597), Expect = 4e-62, Method: Composition-based stats. Identities = 73/253 (28%), Positives = 106/253 (41%), Gaps = 30/253 (11%) Query: 34 IIGGHEVTPHSRPYMASV-RFGGQHHCGGFLLRARWVVSAAHCFSHR------------- 79 I G + P++A + GQ CGG LL + W+V+AAHC Sbjct: 1 IFNGRPAQKGTTPWIAMLSHLNGQPFCGGSLLGSSWIVTAAHCLHQSLDPKDPTLRDSDL 60 Query: 80 -DLRTGLVVLGAHVLSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAV 138 ++LG H ++ +Q G+ T HP Y P T ND+ L+ L S VL V Sbjct: 61 LSPSDFKIILGKHWRLRSDENEQHLGVKHTTLHPQYDPNTFENDVALVELLESPVLNAFV 120 Query: 139 GLLRPPGRRARPPTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSW---KGH 195 + P P G V+GWG + P LME ++ ++D C ++ K Sbjct: 121 MPICLPE---GPQQEGAMVIVSGWGK-QFLQRFPETLMEIEIPIVDHSTCQKAYAPLKKK 176 Query: 196 LTLTMLCTRSGDSHRRGFCSADSGGPLVCRNR------AHGLVSFSGLWCGDPKTPDVYT 249 +T M+C + + C+ DSGGP+V NR G VS+ G CG VY+ Sbjct: 177 VTRDMICAGEKEGGK-DACAGDSGGPMVTLNRERGQWYLVGTVSW-GDDCGKKDRYGVYS 234 Query: 250 QVSAFVAWIWDVV 262 + WI V Sbjct: 235 YIHHNKDWIQRVT 247 >1EQ9-A nrPDB Length = 222 Score = 230 bits (586), Expect = 6e-61, Method: Composition-based stats. Identities = 66/232 (28%), Positives = 100/232 (43%), Gaps = 11/232 (4%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSH-RDLRTGLVVLGAHV 92 I+GG + PY S+R G H CG +L V++AAHC +L V +G + Sbjct: 1 IVGGKDAPVGKYPYQVSLRLSGSHRCGASILDNNNVLTAAHCVDGLSNLNRLKVHVGTNY 60 Query: 93 LSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARPPT 152 LS + V+ ++ + +Y ND+ L+ L V ++ + Sbjct: 61 LSESGD---VYDVEDAVVNKNYDDFLLRNDVALVHLTNPIKFNDLVQPIKLSTNDEDLES 117 Query: 153 AGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWKGHLTLTMLCTRSGDSHRRG 212 C + GWG P L E ++ V C + + + +CT G Sbjct: 118 --NPCTLTGWGSTRLGGNTPNALQEIELIVHPQKQCERD-QWRVIDSHICT--LTKRGEG 172 Query: 213 FCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVRR 264 C DSGGPLV G+VSF G C PDVYT+VS+FV+WI +++ Sbjct: 173 ACHGDSGGPLVANGAQIGIVSF-GSPCAL-GEPDVYTRVSSFVSWINANLKK 222 >5KWM-A nrPDB Length = 230 Score = 229 bits (584), Expect = 1e-60, Method: Composition-based stats. Identities = 61/224 (27%), Positives = 90/224 (40%), Gaps = 9/224 (4%) Query: 34 IIGGHEVTPHSRPYMASVRF-GGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHV 92 I+GG + P+ ++ GQ CGG L VV+AAHC VV G V Sbjct: 1 IVGGEDANVQDHPFTVALVTPDGQQFCGGTLAAPNKVVTAAHCTVGSQPADINVVSGRTV 60 Query: 93 LSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARPPT 152 +S+ E T V + + HP+Y D+ +L L + Sbjct: 61 MSSNEGT--VSKVTNVWVHPEYQDAAKGFDVSVLTLEAPVKE----APIELAKADDAGYA 114 Query: 153 AGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWKGHLTLTMLCTRSGDSHRRG 212 T + GWG S+ + L +A V V D C ++ + M+C + Sbjct: 115 PDTAATILGWGNTSEGGQQADHLQKATVPVNSDDTCKQAYGEYTPDAMVCAGVPEGG-VD 173 Query: 213 FCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVA 256 C DSGGP+V N+ G+ S+ G C P P VY +V A+ Sbjct: 174 TCQGDSGGPMVVNNKLIGVTSW-GEGCARPGKPGVYARVGAYYD 216 >2XRC-A nrPDB Length = 565 Score = 227 bits (578), Expect = 5e-60, Method: Composition-based stats. Identities = 64/248 (25%), Positives = 101/248 (40%), Gaps = 19/248 (7%) Query: 23 VKPPAGSWGAQIIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLR 82 VK +I+GG P+ +++ CGG + W+++AAHC R + Sbjct: 311 VKNRMHIRRKRIVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCL--RASK 368 Query: 83 TGLVVLGAHVLSTAEPTQQVF---GIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVG 139 T + V+ P + +D + H +Y+ T+ NDI L+ + Sbjct: 369 THRYQIWTTVVDWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCEL 428 Query: 140 LLRPPGRRARPP---TAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWKGHL 196 P P C V+GWG D E + L +V+++ C+ + Sbjct: 429 PRSIPACVPWSPYLFQPNDTCIVSGWGREKDNERVFS-LQWGEVKLISN--CSKFYGNRF 485 Query: 197 TLT-MLCTRSGDSHRRGFCSADSGGPLVCRN-----RAHGLVSFSGLWCGDPKTPDVYTQ 250 M C + D C DSGGPLVC + G+VS+ G CG P+ P VYT+ Sbjct: 486 YEKEMECAGTYDG-SIDACKGDSGGPLVCMDANNVTYVWGVVSW-GENCGKPEFPGVYTK 543 Query: 251 VSAFVAWI 258 V+ + WI Sbjct: 544 VANYFDWI 551 >1GPZ-A nrPDB Length = 399 Score = 225 bits (575), Expect = 1e-59, Method: Composition-based stats. Identities = 68/266 (25%), Positives = 104/266 (39%), Gaps = 31/266 (11%) Query: 18 ALMLPVKPPAGSWGAQIIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFS 77 PV P QIIGG + + P+ G+ GG LL RW+++AAH Sbjct: 144 VCGKPVNPVEQR--QQIIGGQKAKMGNFPWQVFTNIHGRG--GGALLGDRWILTAAHTLY 199 Query: 78 HRDLR-----TGLVVLGAHVLSTAEPTQQVFGIDALTTHPDYHPMTHAN---DICLLRLN 129 ++ + V LG + I ++ HPDY N DI LL L Sbjct: 200 PKEHEAQSNASLDVFLGHTNVEELMKLGN-HPIRRVSVHPDYRQDESYNFEGDIALLELE 258 Query: 130 GSAVLGPAVGLLRPPGRRARPPTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCN 189 S LGP + + P G V+G+G + + ++ L ++ V +P C Sbjct: 259 NSVTLGPNLLPICLPDNDTFYD-LGLMGYVSGFGVMEE--KIAHDLRFVRLPVANPQACE 315 Query: 190 SSWKGH-----LTLTMLCTRSGDSHRRGFCSADSGGPLVCRN------RAHGLVSFSGLW 238 + +G + M C S ++ C DSGG R+ A G+VS+ G+ Sbjct: 316 NWLRGKNRMDVFSQNMFCAGHP-SLKQDACQGDSGGVFAVRDPNTDRWVATGIVSW-GIG 373 Query: 239 CGDPKTPDVYTQVSAFVAWIWDVVRR 264 C YT+V +V WI + Sbjct: 374 CSRG--YGFYTKVLNYVDWIKKEMEE 397 >2QY0-B nrPDB Length = 242 Score = 223 bits (570), Expect = 5e-59, Method: Composition-based stats. Identities = 65/252 (25%), Positives = 103/252 (40%), Gaps = 33/252 (13%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLR-----TGLVVL 88 IIGG + + P+ G+ GG LL RW+++AAH ++ + V L Sbjct: 1 IIGGQKAKMGNFPWQVFTNIHGRG--GGALLGDRWILTAAHTLYPKEHEAQSNASLDVFL 58 Query: 89 GAHVLSTAEPTQQV--FGIDALTTHPDYHPMTHAN---DICLLRLNGSAVLGPAVGLLRP 143 G + E ++ I ++ HPDY N DI LL L S LGP + + Sbjct: 59 GHTNV---EELMKLGNHPIRRVSVHPDYRQDESYNFEGDIALLELENSVTLGPNLLPICL 115 Query: 144 PGRRARPPTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWKGH-----LTL 198 P G V+G+G + + ++ L ++ V +P C + +G + Sbjct: 116 PDNDTFYD-LGLMGYVSGFGVMEE--KIAHDLRFVRLPVANPQACENWLRGKNRMDVFSQ 172 Query: 199 TMLCTRSGDSHRRGFCSADSGGPLVCRN------RAHGLVSFSGLWCGDPKTPDVYTQVS 252 M C S ++ C DSGG R+ A G+VS+ G+ C YT+V Sbjct: 173 NMFCAGHP-SLKQDACQGDSGGVFAVRDPNTDRWVATGIVSW-GIGCSRG--YGFYTKVL 228 Query: 253 AFVAWIWDVVRR 264 +V WI + Sbjct: 229 NYVDWIKKEMEE 240 >1MD7-A nrPDB Length = 328 Score = 223 bits (568), Expect = 8e-59, Method: Composition-based stats. Identities = 66/265 (24%), Positives = 104/265 (39%), Gaps = 31/265 (11%) Query: 18 ALMLPVKPPAGSWGAQIIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFS 77 PV P +IIGG + + P+ G+ GG LL RW+++AAH Sbjct: 76 VCGKPVNPVEQR--QRIIGGQKAKMGNFPWQVFTNIHGRG--GGALLGDRWILTAAHTLY 131 Query: 78 HRDLR-----TGLVVLGAHVLSTAEPTQQVFGIDALTTHPDYHPMTHAN---DICLLRLN 129 ++ + V LG + I ++ HPDY N DI LL L Sbjct: 132 PKEHEAQSNASLDVFLGHTNVEELMKLGN-HPIRRVSVHPDYRQDESYNFEGDIALLELE 190 Query: 130 GSAVLGPAVGLLRPPGRRARPPTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCN 189 S LGP + + P G V+G+G + + ++ L ++ V +P C Sbjct: 191 NSVTLGPNLLPICLPDNDTFYD-LGLMGYVSGFGVMEE--KIAHDLRFVRLPVANPQACE 247 Query: 190 SSWKGH-----LTLTMLCTRSGDSHRRGFCSADSGGPLVCRN------RAHGLVSFSGLW 238 + +G + M C S ++ C D+GG R+ A G+VS+ G+ Sbjct: 248 NWLRGKNRMDVFSQNMFCAGHP-SLKQDACQGDAGGVFAVRDPNTDRWVATGIVSW-GIG 305 Query: 239 CGDPKTPDVYTQVSAFVAWIWDVVR 263 C YT+V +V WI + Sbjct: 306 CSRG--YGFYTKVLNYVDWIKKEME 328 >5O32-I nrPDB Length = 244 Score = 222 bits (566), Expect = 1e-58, Method: Composition-based stats. Identities = 62/237 (26%), Positives = 98/237 (41%), Gaps = 19/237 (8%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVL 93 I+GG P+ +++ CGG + W+++AAHC R +T + V+ Sbjct: 1 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCL--RASKTHRYQIWTTVV 58 Query: 94 STAEPTQQVF---GIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARP 150 P + +D + H +Y+ T+ NDI L+ + P Sbjct: 59 DWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPWS 118 Query: 151 P---TAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWKGHLTLT-MLCTRSG 206 P C V+GWG D E + L +V+++ C+ + M C + Sbjct: 119 PYLFQPNDTCIVSGWGREKDNERVFS-LQWGEVKLISN--CSKFYGNRFYEKEMECAGTY 175 Query: 207 DSHRRGFCSADSGGPLVCRN-----RAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWI 258 D C DSGGPLVC + G+VS+ G CG P+ P VYT+V+ + WI Sbjct: 176 DG-SIDACKGDSGGPLVCMDANNVTYVWGVVSW-GENCGKPEFPGVYTKVANYFDWI 230 >3I77-A nrPDB Length = 230 Score = 220 bits (560), Expect = 7e-58, Method: Composition-based stats. Identities = 64/239 (26%), Positives = 94/239 (39%), Gaps = 20/239 (8%) Query: 34 IIGGHEVTPHSRPYMA-SVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHV 92 ++GG P+M + + CGG L V++AAHC S T + G V Sbjct: 1 VVGGTRAAQGEFPFMVRLINEENEGFCGGALYAQDIVLTAAHCVSGSGNNTSITATGGVV 60 Query: 93 LSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARPPT 152 + +V L P + T+ D L++L + P + T Sbjct: 61 DLQSSSAVKVRSTKVLQA-PGFTKETYGKDWALIKLA---------QPINQPTLKIATTT 110 Query: 153 AGTRC--RVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWKGHLTLT-MLCTRSGDSH 209 A + VAGWG + L++A V + C SS L M+C D+ Sbjct: 111 AYNQGTFTVAGWGANREGGSQQRYLLKANVPFVSDAACRSSSSFILVANEMICAGYPDTG 170 Query: 210 RRGFCSADSGGPLVCRNRA-----HGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVR 263 C DSGGP+ ++ A G+VS+ G C P P VYT+VS F + I R Sbjct: 171 GVDTCQGDSGGPMFRKDNADEWIQVGIVSW-GYGCARPGYPGVYTEVSTFASAIASAAR 228 >4LK4-A nrPDB Length = 357 Score = 217 bits (554), Expect = 3e-57, Method: Composition-based stats. Identities = 69/242 (28%), Positives = 106/242 (43%), Gaps = 20/242 (8%) Query: 32 AQIIGGHEVTPHSRPYMASVRFGG-----QHHCGGFLLRARWVVSAAHCFSHRDLRTGLV 86 ++II G P + ++ G CGG L R+V++AAHCF R + V Sbjct: 9 SRIINGSNANSAEWPSIVALVKRGADAYQGQFCGGSFLGGRYVLTAAHCFDSRSAASVDV 68 Query: 87 VLGAHVLSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGR 146 ++GA+ L+ + +++ + H Y P NDI ++ L ++ L PA+ L P R Sbjct: 69 IIGAYDLNNSSQGERI-AAQKIYRHLSYSPSNLLNDIAIVELAQTSSL-PAITLAGPATR 126 Query: 147 RARPPTAGTRCRVAGWGFVSDFEE--LPPGLMEAKVRVLDPDVCNSSWKGHLTL----TM 200 + P A T VAGWG + P L E V ++ +C + ++ T Sbjct: 127 TSLP--ALTPLTVAGWGITVQSKPPQFTPILQEVDVDLVSQSLCQIVMQHGISSDPNSTN 184 Query: 201 LCTRSGDSHRRGFCSADSGGPLVCR-NRAH-GLVSFSGLWCGDPKTPDVYTQVSAFVAWI 258 C + C D+GGP+V + R G+VS+ C T VYT VS F WI Sbjct: 185 FCAARLT---KDSCQGDAGGPIVVKTGREQLGIVSWGDEQCAKTGTYGVYTNVSYFRDWI 241 Query: 259 WD 260 Sbjct: 242 TK 243 >2OLG-A nrPDB Length = 278 Score = 217 bits (553), Expect = 5e-57, Method: Composition-based stats. Identities = 72/274 (26%), Positives = 109/274 (39%), Gaps = 35/274 (12%) Query: 20 MLPVKPPAGSWGAQIIGGHEVTPHSRPYMASVRFGG-----QHHCGGFLLRARWVVSAAH 74 +LP +I+ G + P P+ A + + Q CGG L+ R++V+AAH Sbjct: 9 LLPNDCGYQVEADKILNGDDTVPEEFPWTAMIGYKNSSNFEQFACGGSLINNRYIVTAAH 68 Query: 75 CFSHRDLRTG----LVVLGAHVLSTAE----------PTQQV-FGIDALTTHPDYHPMTH 119 C + R LR V LG +T P + + GI+ HPDY + Sbjct: 69 CVAGRVLRVVGALNKVRLGEWNTATDPDCYGAVRVCVPDKPIDLGIEETIQHPDYVDGSK 128 Query: 120 A--NDICLLRLNGSAVLGPAVGLLRPPGRRARPPTAGTRCRVAGWGFVSDFEELPPGLME 177 +DI L+RLN + + P + G R V GWG + + + Sbjct: 129 DRYHDIALIRLNRQVEFTNYIRPVCLP-QPNEEVQVGQRLTVVGWGRT-ETGQYSTIKQK 186 Query: 178 AKVRVLDPDVCNSSWKG---HLTLTMLCTRSGDSHRRGFCSADSGGPLVCRNRAH----- 229 V V+ + C ++ + + LC + C DSGGPL+ Sbjct: 187 LAVPVVHAEQCAKTFGAAGVRVRSSQLCAGG--EKAKDSCGGDSGGPLLAERANQQFFLE 244 Query: 230 GLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVR 263 GLVSF G CG P +YT+V + WI +R Sbjct: 245 GLVSF-GATCGTEGWPGIYTKVGKYRDWIEGNIR 277 >6BQM-A nrPDB Length = 506 Score = 216 bits (550), Expect = 9e-57, Method: Composition-based stats. Identities = 63/247 (25%), Positives = 101/247 (40%), Gaps = 25/247 (10%) Query: 32 AQIIGGHEVTPHSRPYMASVRFGGQH--HCGGFLLRARWVVSAAHCFSHRDLRTGLVVLG 89 ++IIGG + T PYM ++ CGG L R+V++AAHC D G V+LG Sbjct: 9 SRIIGGEQATAGEWPYMVALTARNSSHVFCGGSYLGGRYVLTAAHCVDKEDPAKGDVLLG 68 Query: 90 AHVLSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRAR 149 A ++ +++ + + H Y + NDI +L L + +V + Sbjct: 69 AFDMNDVNTAERIH-VRQIYVHNSYITASMGNDIAVLELERDPLPRRSVQI--SDSSDFN 125 Query: 150 PPTAGTRCRVAGWGFVSDFEE----LPPGLMEAKVRVLDPDVCN--------SSWKGHLT 197 T + V G+G + + L + +V + C + LT Sbjct: 126 ELTKDSPMTVIGFGNRKEVDGEKSDPATILHQVQVPFVPLPECKTKGSDQDAKNNYSQLT 185 Query: 198 LTMLCTRSGDSHRRGFCSADSGGPLVCRNR----AHGLVSFSGLWCGDPKTPDVYTQVSA 253 C S + CS D+GGP+ + G+VS+ G CG +P VYT +S Sbjct: 186 NNAFCAG---SFGKDACSGDAGGPIFFDSNNGRKQMGVVSW-GDGCGRANSPGVYTNLSV 241 Query: 254 FVAWIWD 260 F W+ D Sbjct: 242 FNDWLDD 248 >1SI5-H nrPDB Length = 240 Score = 215 bits (548), Expect = 2e-56, Method: Composition-based stats. Identities = 64/238 (26%), Positives = 104/238 (43%), Gaps = 21/238 (8%) Query: 34 IIGG--HEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAH 91 ++ G +M S+R+ +H CGG L++ WV++A CF RDL+ LG H Sbjct: 1 VVNGIPTRTNIG---WMVSLRYRNKHICGGSLIKESWVLTARQCFPSRDLKDYEAWLGIH 57 Query: 92 VL--STAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRAR 149 + E +QV + L P+ +D+ L++L AVL V + P + Sbjct: 58 DVHGRGDEKCKQVLNVSQLVYGPE------GSDLVLMKLARPAVLDDFVSTIDLPNYGST 111 Query: 150 PPTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWKGHLTLT--MLCTRSGD 207 P T C V GWG+ L A + ++ + C+ +G +TL +C + + Sbjct: 112 IPEK-TSCSVYGWGYTGLI-NYDGLLRVAHLYIMGNEKCSQHHRGKVTLNESEICAGA-E 168 Query: 208 SHRRGFCSADSGGPLVCRNRAHGL---VSFSGLWCGDPKTPDVYTQVSAFVAWIWDVV 262 G C D GGPLVC + V G C P P ++ +V+ + WI ++ Sbjct: 169 KIGSGPCEGDYGGPLVCEQHKMRMVLGVIVPGRGCAIPNRPGIFVRVAYYAKWIHKII 226 >5UBM-A nrPDB Length = 252 Score = 215 bits (547), Expect = 3e-56, Method: Composition-based stats. Identities = 60/259 (23%), Positives = 98/259 (37%), Gaps = 37/259 (14%) Query: 33 QIIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHV 92 +IIGG + + P+ GG L+ WV++AAH R + +G+ Sbjct: 1 RIIGGSDADIKNFPWQVFF---DNPWAGGALINEYWVLTAAHVVEGN--REPTMYVGSTS 55 Query: 93 LSTAEPTQ-QVFGIDALTTHPDYH-------PMTHANDICLLRLNGSAVLGPAVGLLRPP 144 + T+ + ++ + + HP + NDI L+RL +GP V + P Sbjct: 56 VQTSRLAKSKMLTPEHVFIHPGWKLLEVPEGRTNFDNDIALVRLKDPVKMGPTVSPICLP 115 Query: 145 GRRAR-PPTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNS---------SWKG 194 G + G ++GWG + L A++ V C + Sbjct: 116 GTSSDYNLMDGDLGLISGWGRTEKRDR-AVRLKAARLPVAPLRKCKEVKVEKPTADAEAY 174 Query: 195 HLTLTMLCTRSGDSHRRGFCSADSGGPLVCRN-------RAHGLVSFSGLWCGDPKTPDV 247 T M+C C DSGG ++ A GLVS+ G CG + Sbjct: 175 VFTPNMICAGG--EKGMDSCKGDSGGAFAVQDPNDKTKFYAAGLVSW-GPQCGT---YGL 228 Query: 248 YTQVSAFVAWIWDVVRRSS 266 YT+V +V WI ++ +S Sbjct: 229 YTRVKNYVDWIMKTMQENS 247 >2B9L-A nrPDB Length = 394 Score = 214 bits (545), Expect = 4e-56, Method: Composition-based stats. Identities = 64/268 (23%), Positives = 100/268 (37%), Gaps = 34/268 (12%) Query: 33 QIIGGH-EVTPHSRPYMASVRFGG--------QHHCGGFLLRARWVVSAAHCF--SHRDL 81 +I G E P+M +V Q CGG L+ V++ AHC +L Sbjct: 129 KITGQTNEAEYGEFPWMVAVLKANVIPGSGEEQLVCGGSLIAPSVVLTGAHCVNSYQSNL 188 Query: 82 RTGLVVLGAHVLSTAEP--TQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVG 139 + G T + Q I + H +++P T ND+ LL L+ V +G Sbjct: 189 DAIKIRAGEWDTLTEKERLPYQERKIRQVIIHSNFNPKTVVNDVALLLLDRPLVQADNIG 248 Query: 140 LLRPPGRRARPPTAGTRCRVAGWGFVS--DFEELPPGLMEAKVRVLDPDVCNSSWKGH-- 195 + P + + T C +GWG L + ++ +D D C + + Sbjct: 249 TICLPQQSQIFDS--TECFASGWGKKEFGSRHRYSNILKKIQLPTVDRDKCQADLRNTRL 306 Query: 196 -----LTLTMLCTRSGDSHRRGFCSADSGGPLVC-------RNRAHGLVSFSGLWCGDPK 243 L T +C + C+ D G PL C R G+V++ G+ CGD Sbjct: 307 GLKFVLDQTFVCAGG--EQGKDTCTGDGGSPLFCPDPRNPSRYMQMGIVAW-GIGCGDEN 363 Query: 244 TPDVYTQVSAFVAWIWDVVRRSSPQPGP 271 P VY V+ F WI ++ P Sbjct: 364 VPGVYANVAHFRNWIDQEMQAKGLSTTP 391 >1ELV-A nrPDB Length = 333 Score = 212 bits (539), Expect = 2e-55, Method: Composition-based stats. Identities = 60/262 (22%), Positives = 98/262 (37%), Gaps = 37/262 (14%) Query: 30 WGAQIIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLG 89 +IIGG + + P+ GG L+ WV++AAH R + +G Sbjct: 79 EKQRIIGGSDADIKNFPWQVFF---DNPWAGGALINEYWVLTAAHVVEGN--REPTMYVG 133 Query: 90 AHVLSTAEPTQ-QVFGIDALTTHPDYH-------PMTHANDICLLRLNGSAVLGPAVGLL 141 + + T+ + ++ + + HP + NDI L+RL +GP V + Sbjct: 134 STSVQTSRLAKSKMLTPEHVFIHPGWKLLAVPEGRTNFDNDIALVRLKDPVKMGPTVSPI 193 Query: 142 RPPGRRAR-PPTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNS---------S 191 PG + G ++GWG + L A++ V C + Sbjct: 194 CLPGTSSDYNLMDGDLGLISGWGRTEKRDR-AVRLKAARLPVAPLRKCKEVKVEKPTADA 252 Query: 192 WKGHLTLTMLCTRSGDSHRRGFCSADSGGPLVCRN-------RAHGLVSFSGLWCGDPKT 244 T M+C C DSGG ++ A GLVS+ G CG Sbjct: 253 EAYVFTPNMICAGG--EKGMDSCKGDSGGAFAVQDPNDKTKFYAAGLVSW-GPQCGT--- 306 Query: 245 PDVYTQVSAFVAWIWDVVRRSS 266 +YT+V +V WI ++ +S Sbjct: 307 YGLYTRVKNYVDWIMKTMQENS 328 >1PQ7-A nrPDB Length = 224 Score = 210 bits (536), Expect = 5e-55, Method: Composition-based stats. Identities = 68/229 (29%), Positives = 100/229 (43%), Gaps = 11/229 (4%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVL 93 I+GG + P++ S+ G CGG LL A V++AAHC S + G L Sbjct: 1 IVGGTSASAGDFPFIVSISRNGGPWCGGSLLNANTVLTAAHCVSGYAQSGFQIRAG--SL 58 Query: 94 STAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARPPTA 153 S + ++ HP Y + ND+ +L+L+ S G +G R + P A Sbjct: 59 SRTSGGI-TSSLSSVRVHPSYS--GNNNDLAILKLSTSIPSGGNIGYARLAASGSDPV-A 114 Query: 154 GTRCRVAGWGFVSDFEELPPG-LMEAKVRVLDPDVCNSSWK-GHLTLTMLCTRSGDSHRR 211 G+ VAGWG S+ P L++ V ++ C + + +T M C S + Sbjct: 115 GSSATVAGWGATSEGGSSTPVNLLKVTVPIVSRATCRAQYGTSAITNQMFCAGVS-SGGK 173 Query: 212 GFCSADSGGPLV-CRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIW 259 C DSGGP+V N G VS+ G C P VY V A ++I Sbjct: 174 DSCQGDSGGPIVDSSNTLIGAVSW-GNGCARPNYSGVYASVGALRSFID 221 >3BEU-A nrPDB Length = 224 Score = 209 bits (533), Expect = 1e-54, Method: Composition-based stats. Identities = 63/238 (26%), Positives = 93/238 (39%), Gaps = 24/238 (10%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVL 93 ++GG P+M + G CGG L V++AAHC S T + G V Sbjct: 1 VVGGTRAAQGEFPFMVRLSMG----CGGALYAQDIVLTAAHCVSGSGNNTSITATGGVVD 56 Query: 94 STAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARPPTA 153 + +V L P + T+ D L++L + P + TA Sbjct: 57 LQSSSAVKVRSTKVLQA-PGFTKETYGKDWALIKLA---------QPINQPTLKIATTTA 106 Query: 154 GTRCR--VAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWKGHLTLT-MLCTRSGDSHR 210 + VAGWG + L++A V + C SS L M+C D+ + Sbjct: 107 YNQGTFTVAGWGANREGGSQQRYLLKANVPFVSDAACRSSSSFILVANEMICAGY-DTKQ 165 Query: 211 RGFCSADSGGPLVCRNRA-----HGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVR 263 C DSGGP+ ++ A G+VS+ G C VYT+VS F + I R Sbjct: 166 EDTCQGDSGGPMFRKDNADEWVQVGIVSW-GEGCARKGKYGVYTEVSTFASAIASAAR 222 >4J1Y-A nrPDB Length = 397 Score = 207 bits (526), Expect = 7e-54, Method: Composition-based stats. Identities = 60/262 (22%), Positives = 98/262 (37%), Gaps = 37/262 (14%) Query: 30 WGAQIIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLG 89 A+ IGG + + P+ GG L+ WV++AAH R + +G Sbjct: 143 EKARAIGGSDADIKNFPWQVFF---DNPWAGGALINEYWVLTAAHVVEGN--REPTMYVG 197 Query: 90 AHVLSTAEPTQ-QVFGIDALTTHPDYH-------PMTHANDICLLRLNGSAVLGPAVGLL 141 + + T+ + ++ + + HP + NDI L+RL +GP V + Sbjct: 198 STSVQTSRLAKSKMLTPEHVFIHPGWKLLEVPEGRTNFDNDIALVRLKDPVKMGPTVSPI 257 Query: 142 RPPGRRAR-PPTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNS---------S 191 PG + G ++GWG + L A++ V C + Sbjct: 258 CLPGTSSDYNLMDGDLGLISGWGRTEKRDR-AVRLKAARLPVAPLRKCKEVKVEKPTADA 316 Query: 192 WKGHLTLTMLCTRSGDSHRRGFCSADSGGPLVCRN-------RAHGLVSFSGLWCGDPKT 244 T M+C C DSGG ++ A GLVS+ G CG Sbjct: 317 EAYVFTPNMICAGG--EKGMDSCKGDSGGAFAVQDPNDKTKFYAAGLVSW-GPQCGT--- 370 Query: 245 PDVYTQVSAFVAWIWDVVRRSS 266 +YT+V +V WI ++ +S Sbjct: 371 YGLYTRVKNYVDWIMKTMQENS 392 >2ASU-B nrPDB Length = 234 Score = 206 bits (525), Expect = 7e-54, Method: Composition-based stats. Identities = 72/239 (30%), Positives = 105/239 (43%), Gaps = 22/239 (9%) Query: 34 IIGGHEVTPHSRPYMASVRFG-GQHHCGGFLLRARWVVSAAHCFS--HRDLRTGLVVLGA 90 ++GGH P + P+ S+R GQH CGG L++ +W+++A CFS H L V LG Sbjct: 1 VVGGH---PGNSPWTVSLRNRQGQHFCGGSLVKEQWILTARQCFSSCHMPLTGYEVWLGT 57 Query: 91 --HVLSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRA 148 EP+ Q + + P + + LL+L S L V L+ P Sbjct: 58 LFQNPQHGEPSLQRVPVAKMVCGPS------GSQLVLLKLERSVTLNQRVALICLPP-EW 110 Query: 149 RPPTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWKGHLTLTMLCTRSGDS 208 GT+C +AGWG L A + V+ CN +G + + +CT + Sbjct: 111 YVVPPGTKCEIAGWGETKGTGN-DTVLNVALLNVISNQECNIKHRGRVRESEMCTEGLLA 169 Query: 209 HRRGFCSADSGGPLVC----RNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVR 263 G C D GGPL C G++ C + P V+T+VS FV WI V+R Sbjct: 170 -PVGACEGDYGGPLACFTHNSWVLEGII-IPNRVCARSRWPAVFTRVSVFVDWIHKVMR 226 >2FMJ-A nrPDB Length = 222 Score = 202 bits (515), Expect = 1e-52, Method: Composition-based stats. Identities = 60/237 (25%), Positives = 89/237 (37%), Gaps = 24/237 (10%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVL 93 ++GG P+M + G CGG L V++AAHC S T + G V Sbjct: 1 VVGGTRAAQGEFPFMVRLSMG----CGGALYAQDIVLTAAHCVSGSGNNTSITATGGVVD 56 Query: 94 STAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARPPTA 153 + +V L P Y+ D L++L + P + TA Sbjct: 57 LQSSSAVKVRSTKVLQA-PGYNGT--GKDWALIKLA---------QPINQPTLKIATTTA 104 Query: 154 GTRCR--VAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWKGHLTLTMLCTRSGDSHRR 211 + VAGWG + L++A V + C S++ L D+ Sbjct: 105 YNQGTFTVAGWGANREGGSQQRYLLKANVPFVSDAACRSAYGNELVANEEICAGYDTGGV 164 Query: 212 GFCSADSGGPLVCRNRA-----HGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVR 263 C DSGGP+ ++ A G+VS+ G C VYT+VS F + I R Sbjct: 165 DTCQGDSGGPMFRKDNADEWIQVGIVSW-GEGCARKGKYGVYTEVSTFASAIASAAR 220 >2HLC-A nrPDB Length = 230 Score = 202 bits (514), Expect = 2e-52, Method: Composition-based stats. Identities = 62/236 (26%), Positives = 106/236 (44%), Gaps = 21/236 (8%) Query: 34 IIGGHEVTPHSRPYMASV----RFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLG 89 II G+E PY A + + + CGG L+ +W+++AAHC D + +V LG Sbjct: 1 IINGYEAYTGLFPYQAGLDITLQDQRRVWCGGSLIDNKWILTAAHCVH--DAVSVVVYLG 58 Query: 90 AHVLSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPG-RRA 148 + V E V + + +H ++P T+ ND+ L+++ + +R P Sbjct: 59 SAVQYEGEA---VVNSERIISHSMFNPDTYLNDVALIKIPH-VEYTDNIQPIRLPSGEEL 114 Query: 149 RPPTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSW-KGHLTLTMLCTRSGD 207 V+GWG + + L V+D D C + G + + +C + D Sbjct: 115 NNKFENIWATVSGWGQSNTDTVI---LQYTYNLVIDNDRCAQEYPPGIIVESTICGDTSD 171 Query: 208 SHRRGFCSADSGGPLVC--RNRAHGLVSF-SGLWCGDPKTPDVYTQVSAFVAWIWD 260 + C DSGGP V +N G+VSF SG C + P +++V++++ WI Sbjct: 172 G--KSPCFGDSGGPFVLSDKNLLIGVVSFVSGAGC-ESGKPVGFSRVTSYMDWIQQ 224 >2PKA-B nrPDB Length = 152 Score = 191 bits (487), Expect = 2e-49, Method: Composition-based stats. Identities = 42/154 (27%), Positives = 70/154 (45%), Gaps = 7/154 (4%) Query: 115 HPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARPPTAGTRCRVAGWGFVSDFE---EL 171 +++D+ LLRL A + AV +L P + P G+ C +GWG + E Sbjct: 2 DGKDYSHDLMLLRLQSPAKITDAVKVLELPTQE---PELGSTCEASGWGSIEPGPDDFEF 58 Query: 172 PPGLMEAKVRVLDPDVCNSSWKGHLTLTMLCTRSGDSHRRGFCSADSGGPLVCRNRAHGL 231 P + ++ +L C + +T +MLC + C DSGGPL+C G+ Sbjct: 59 PDEIQCVQLTLLQNTFCADAHPDKVTESMLCAGYLPGGK-DTCMGDSGGPLICNGMWQGI 117 Query: 232 VSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVRRS 265 S+ CG P +YT++ ++ WI D + + Sbjct: 118 TSWGHTPCGSANKPSIYTKLIFYLDWIDDTITEN 151 >1M9U-A nrPDB Length = 241 Score = 191 bits (485), Expect = 4e-49, Method: Composition-based stats. Identities = 74/242 (30%), Positives = 109/242 (45%), Gaps = 18/242 (7%) Query: 34 IIGGHEVTPHSRPYMASVRFGG---QHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGA 90 +IGG +P P+ S + H CG LL + +SA+HC V+ G Sbjct: 1 VIGGTNASPGEFPWQLSQQRQSGSWSHSCGASLLSSTSALSASHCVDGVLPNNIRVIAGL 60 Query: 91 HVLSTAEPTQQVFGIDALTTHPDYHPMT--HANDICLLRLNGSAVLGPAVGLLRPPGRRA 148 S T Q +D+ T H +Y T ++NDI +L L S LG + P Sbjct: 61 WQQSDTSGT-QTANVDSYTMHENYGAGTASYSNDIAILHLATSISLGGNIQAAVLPAN-N 118 Query: 149 RPPTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWKG----HLTLTMLCTR 204 AGT C ++GWG LP L ++ + V+ C ++ G ++ +C + Sbjct: 119 NNDYAGTTCVISGWGRTDGTNNLPDILQKSSIPVITTAQCTAAMVGVGGANIWDNHICVQ 178 Query: 205 SGDSHRRGFCSADSGGPLVCRN---RAHGLVSF---SGLWCGDPKTPDVYTQVSAFVAWI 258 + G C+ DSGGPL C + R G+ S+ SGL P P VYT+VSA++ WI Sbjct: 179 DPAGN-TGACNGDSGGPLNCPDGGTRVVGVTSWVVSSGLGACLPDYPSVYTRVSAYLGWI 237 Query: 259 WD 260 D Sbjct: 238 GD 239 >3H7T-A nrPDB Length = 235 Score = 188 bits (479), Expect = 2e-48, Method: Composition-based stats. Identities = 55/242 (22%), Positives = 88/242 (36%), Gaps = 14/242 (5%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVL 93 IIGG + P+ V + CGG +L A +V++AA C + H Sbjct: 1 IIGGKKSDITKEPWAVGVLVDEKPFCGGSILTANFVITAAQCVDGTKPSDISI----HYG 56 Query: 94 STAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARPPTA 153 S+ T+ + YHP+T N+ ++ L P Sbjct: 57 SSYRTTKGTSVMAKKIYIVRYHPLTMQNNYAVIETEMPIKLDDKTTKKIELPSLLYDPEP 116 Query: 154 GTRCRVAGWGFVSDFE-ELPPGLMEAKVRVLDPDVCNSSWKG-----HLTLTMLCTRSGD 207 T V+GWG + E LMEA V+D C +K ++ + C G+ Sbjct: 117 DTSVLVSGWGSTNFKSLEYSGDLMEANFTVVDRKSCEEQYKQIEADKYIYDGVFCAG-GE 175 Query: 208 SHRRGFCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVR-RSS 266 D+G P V G+ S+ + P V+ +V +V I D++ + Sbjct: 176 YDETYIGYGDAGDPAVQNGTLVGVASYISS--MPSEFPSVFLRVGYYVLDIKDIISGKVK 233 Query: 267 PQ 268 PQ Sbjct: 234 PQ 235 >3H7O-A nrPDB Length = 228 Score = 184 bits (467), Expect = 4e-47, Method: Composition-based stats. Identities = 55/235 (23%), Positives = 101/235 (42%), Gaps = 13/235 (5%) Query: 36 GGHEVTPHSRPYMASVRF---GGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHV 92 GG + P+ +VR CGG +L +V++AAHC + T ++ + Sbjct: 2 GGEKTDIKQVPWTVAVRTYPGEESLTCGGAILSQWFVLTAAHCVFDQKPETIVIQYESTN 61 Query: 93 LSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGP-AVGLLRPPGRRARPP 151 L +P + + + Y T NDI +L L+ L + P RP Sbjct: 62 L-WEDPGKSDPYVSHVYL-SFYRQETMENDIAILELSRPLKLDGLKSKPAKLPDIEFRPK 119 Query: 152 TAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSW-KGHLTLTMLCTRSGDSHR 210 T G+ V+G+G + L A++ V+D D C + + L+L + C + Sbjct: 120 T-GSDVLVSGYGDGQTMDPKDHDLKSAQLTVVDLDECRTKYGPIFLSLQVFCAQKVGVSL 178 Query: 211 RGFCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVRRS 265 D+G P V ++ G+ ++ P+V+T+V ++V+WI D++++ Sbjct: 179 ES---GDAGDPTVQQDTLVGVAAYF--PKRPEGAPEVFTKVGSYVSWIQDIIKKK 228 >5XW8-A nrPDB Length = 133 Score = 181 bits (461), Expect = 2e-46, Method: Composition-based stats. Identities = 49/136 (36%), Positives = 70/136 (51%), Gaps = 8/136 (5%) Query: 31 GAQIIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGA 90 +I+GG+ +S PY S+ G H CGG L+ ++WVVSAAHC+ R V LG Sbjct: 6 DDKIVGGYTCAANSIPYQVSLN-SGSHFCGGSLINSQWVVSAAHCYKSR----IQVRLGE 60 Query: 91 HVLSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARP 150 H + E +Q + THP+++ T NDI L++L+ A L V + P A Sbjct: 61 HNIDVLEGNEQFINAAKIITHPNFNGNTLDNDIMLIKLSSPATLNSRVATVSLPRSCA-- 118 Query: 151 PTAGTRCRVAGWGFVS 166 AGT C ++GWG Sbjct: 119 -AAGTECLISGWGNTK 133 >3VGC-B nrPDB Length = 131 Score = 161 bits (409), Expect = 2e-40, Method: Composition-based stats. Identities = 43/134 (32%), Positives = 62/134 (46%), Gaps = 5/134 (3%) Query: 34 IIGGHEVTPHSRPYMASVRF-GGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHV 92 I+ G E P S P+ S++ G H CGG L+ WVV+AAHC + +VV G Sbjct: 1 IVNGEEAVPGSWPWQVSLQDKTGFHFCGGSLINENWVVTAAHC---GVTTSDVVVAGEFD 57 Query: 93 LSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARPPT 152 ++ Q I + + Y+ +T NDI LL+L+ +A V + P + Sbjct: 58 QGSSSEKIQKLKIAKVFKNSKYNSLTINNDITLLKLSTAASFSQTVSAVCLPS-ASDDFA 116 Query: 153 AGTRCRVAGWGFVS 166 AGT C GWG Sbjct: 117 AGTTCVTTGWGLTR 130 >4X0L-C nrPDB Length = 259 Score = 161 bits (409), Expect = 2e-40, Method: Composition-based stats. Identities = 53/265 (20%), Positives = 94/265 (35%), Gaps = 34/265 (12%) Query: 24 KPPAGSWGAQIIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRT 83 K PA +I+GGH S P+ A + G L+ +W+++ A Sbjct: 6 KNPANPVQ-RILGGHLDAKGSFPWQAKMVSHHNLTTGATLINEQWLLTTAKNLFLNHSEN 64 Query: 84 GLVVLGAHVLSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRP 143 A L+ +Q+ I+ + HP+Y + DI L++L + V + Sbjct: 65 ATAKDIAPTLTLYVGKKQLVEIEKVVLHPNYSQV----DIGLIKLKQKVSVNERVMPICL 120 Query: 144 PGRRARPPTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWKGH-------- 195 P + G V+GWG ++F + L + V D D C ++G Sbjct: 121 PSKDYA--EVGRVGYVSGWGRNANF-KFTDHLKYVMLPVADQDQCIRHYEGSTVPEKKTP 177 Query: 196 ---------LTLTMLCTRSGDSHRRGFCSADSGGPLVCRN------RAHGLVSFSGLWCG 240 L C ++ C D+G + A G++SF C Sbjct: 178 KSPVGVQPILNEHTFCAG-MSKYQEDTCYGDAGSAFAVHDLEEDTWYATGILSF-DKSCA 235 Query: 241 DPKTPDVYTQVSAFVAWIWDVVRRS 265 + VY +V++ W+ + + Sbjct: 236 VAE-YGVYVKVTSIQDWVQKTIAEN 259 >4WJG-C nrPDB Length = 315 Score = 161 bits (407), Expect = 4e-40, Method: Composition-based stats. Identities = 54/282 (19%), Positives = 96/282 (34%), Gaps = 37/282 (13%) Query: 7 GWGRPLLTVATALMLPVKPPAGSWGAQIIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRA 66 G P P P + +I+GGH S P+ A + G L+ Sbjct: 48 GDKLPEC--EAVCGKPKNPA--NPVQRILGGHLDAKGSFPWQAKMVSHHNLTTGATLINE 103 Query: 67 RWVVSAAHCFSHRDLRTGLVVLGAHVLSTAEPTQQVFGIDALTTHPDYHPMTHANDICLL 126 +W+++ A A L+ +Q+ I+ + HP+Y + DI L+ Sbjct: 104 QWLLTTAKNLFLNHSENATAKDIAPTLTLYVGKKQLVEIEKVVLHPNYSQV----DIGLI 159 Query: 127 RLNGSAVLGPAVGLLRPPGRRARPPTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPD 186 +L + V + P + G V+GWG ++F + L + V D D Sbjct: 160 KLKQKVSVNERVMPICLPSKDYA--EVGRVGYVSGWGRNANF-KFTDHLKYVMLPVADQD 216 Query: 187 VCNSSWKGH-----------------LTLTMLCTRSGDSHRRGFCSADSGGPLVCRN--- 226 C ++G L C ++ C D+G + Sbjct: 217 QCIRHYEGSTVPEKKTPKSPVGVQPILNEHTFCAG-MSKYQEDTCYGDAGSAFAVHDLEE 275 Query: 227 ---RAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVRRS 265 A G++SF C + VY +V++ W+ + + Sbjct: 276 DTWYATGILSF-DKSCAVAE-YGVYVKVTSIQDWVQKTIAEN 315 >2JET-B nrPDB Length = 128 Score = 158 bits (399), Expect = 3e-39, Method: Composition-based stats. Identities = 43/131 (32%), Positives = 58/131 (44%), Gaps = 5/131 (3%) Query: 37 GHEVTPHSRPYMASVRF-GGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVLST 95 G + P S P+ S++ G H CGG L+ WVV+AAHC + +VV G + Sbjct: 1 GEDAIPGSWPWQVSLQDKTGFHFCGGSLISEDWVVTAAHC---GVKTSDVVVAGEFDQGS 57 Query: 96 AEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARPPTAGT 155 E QV I + +P ++ T NDI LL+L A V + P P GT Sbjct: 58 DEENIQVLKIAQVFKNPKFNMFTVRNDITLLKLATPAQFSETVSAVCLPNVDDDFP-PGT 116 Query: 156 RCRVAGWGFVS 166 C GWG Sbjct: 117 VCATTGWGKTK 127 >4F4O-C nrPDB Length = 347 Score = 155 bits (392), Expect = 2e-38, Method: Composition-based stats. Identities = 53/294 (18%), Positives = 94/294 (31%), Gaps = 57/294 (19%) Query: 5 LRGWGRPLLTVATALMLPVKPPAGSWGAQIIGGHEVTPHSRPYMASVRFGGQHHCGGFLL 64 + G P P P +I+GG S P+ A + G L+ Sbjct: 78 VTGEKLPEC--EAVCGKPKNPVDQV--QRIMGGSLDAKGSFPWQAKMISHHNLTSGATLI 133 Query: 65 RARWVVSAAHCFSHRDLRTGLVVLGAHV----------LSTAEPTQQVFGIDALTTHPDY 114 +W+++ A + LG L +Q I+ + HPD Sbjct: 134 NEQWLLTTA----------KNLRLGHKNDTKAKDIAPTLRLYVGKKQEVEIEKVIFHPDN 183 Query: 115 HPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARPPTAGTRCRVAGWGFVSDFEELPPG 174 + DI L++L + V + P + G V+GWG ++ Sbjct: 184 STV----DIGLIKLKQKVPVNERVMPICLPSKD--YVNVGLVGYVSGWGRNANL-NFTEH 236 Query: 175 LMEAKVRVLDPDVCNSSWKGH-----------------LTLTMLCTRSGDSHRRGFCSAD 217 L + V D + C ++G L C ++ C D Sbjct: 237 LKYVMLPVADQEKCVQYYEGSTVPEKKTPKSPVGVQPILNEHTFCAG-LSKYQEDTCYGD 295 Query: 218 SGGPLVCRNR------AHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVRRS 265 +G ++ A G++SF C + VY +V++ + WI + + Sbjct: 296 AGSAFAVHDKDDDTWYAAGILSF-DKSCRTAE-YGVYVRVTSILDWIQTTIADN 347 >1RIW-B nrPDB Length = 147 Score = 152 bits (385), Expect = 1e-37, Method: Composition-based stats. Identities = 34/147 (23%), Positives = 59/147 (40%), Gaps = 12/147 (8%) Query: 34 IIGGHEVTPHSRPYMASVRFGG--QHHCGGFLLRARWVVSAAHCFSHRDL------RTGL 85 I+ G + P+ + + CG L+ RWV++AAHC + L Sbjct: 1 IVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLL 60 Query: 86 VVLGAHVLSTAEPT-QQVFGIDALTTHPDYHP-MTHANDICLLRLNGSAVLGPAVGLLRP 143 V +G H + E +++ ++ + HP Y+ DI L++L + + Sbjct: 61 VRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCL 120 Query: 144 PGRRA--RPPTAGTRCRVAGWGFVSDF 168 P R AG + RV GWG + + Sbjct: 121 PDRETAASLLQAGYKGRVTGWGNLKET 147 >1BBR-H nrPDB Length = 150 Score = 150 bits (379), Expect = 7e-37, Method: Composition-based stats. Identities = 36/147 (24%), Positives = 60/147 (40%), Gaps = 12/147 (8%) Query: 34 IIGGHEVTPHSRPYMASVRFGG--QHHCGGFLLRARWVVSAAHCFSHRDL------RTGL 85 I+ G + P+ + + CG L+ RWV++AAHC + L Sbjct: 1 IVEGQDAEVGLSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTVDDLL 60 Query: 86 VVLGAHVLSTAE-PTQQVFGIDALTTHPDYHP-MTHANDICLLRLNGSAVLGPAVGLLRP 143 V +G H + E +++ +D + HP Y+ DI LL+L L + + Sbjct: 61 VRIGKHSRTRYERKVEKISMLDKIYIHPRYNWKENLDRDIALLKLKRPIELSDYIHPVCL 120 Query: 144 PGRRAR--PPTAGTRCRVAGWGFVSDF 168 P ++ AG + RV GWG + Sbjct: 121 PDKQTAAKLLHAGFKGRVTGWGNRRET 147 >1AKS-B nrPDB Length = 98 Score = 147 bits (371), Expect = 6e-36, Method: Composition-based stats. Identities = 34/100 (34%), Positives = 46/100 (46%), Gaps = 2/100 (2%) Query: 166 SDFEELPPGLMEAKVRVLDPDVCNSSWKGHLTLTMLCTRSGDSHRRGFCSADSGGPLVCR 225 S P L K VL C SS+ G +T M+C + C DSGGP+VC Sbjct: 1 SSGSSYPSLLQCLKAPVLSNSSCKSSYPGQITGNMICVGFLQGGK-DSCQGDSGGPVVCN 59 Query: 226 NRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVRRS 265 + G+VS+ G C P VYT+V +V WI + + Sbjct: 60 GQLQGIVSW-GYGCAQKNKPGVYTKVCNYVNWIQQTIAAN 98 >1BBR-E nrPDB Length = 109 Score = 123 bits (309), Expect = 1e-28, Method: Composition-based stats. Identities = 31/107 (28%), Positives = 43/107 (40%), Gaps = 9/107 (8%) Query: 166 SDFEELPPGLMEAKVRVLDPDVCNSSWKGHLTLTMLCTRS--GDSHRRGFCSADSGGPLV 223 S E P L + +++ VC +S + +T M C G+ R C DSGGP V Sbjct: 1 SVAEVQPSVLQVVNLPLVERPVCKASTRIRITDNMFCAGYKPGEGKRGDACEGDSGGPFV 60 Query: 224 CR------NRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVRR 264 + G+VS+ G C YT V WI V+ R Sbjct: 61 MKSPYNNRWYQMGIVSW-GEGCDRDGKYGFYTHVFRLKKWIQKVIDR 106 >2KAI-A nrPDB Length = 80 Score = 122 bits (307), Expect = 1e-28, Method: Composition-based stats. Identities = 30/82 (36%), Positives = 41/82 (50%), Gaps = 4/82 (4%) Query: 34 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVL 93 IIGG E +S P+ ++ CGG L+ +WV++AAHC V LG H L Sbjct: 1 IIGGRECEKNSHPWQVAIYHYSSFQCGGVLVNPKWVLTAAHC----KNDNYEVWLGRHNL 56 Query: 94 STAEPTQQVFGIDALTTHPDYH 115 E T Q FG+ A HP ++ Sbjct: 57 FENENTAQFFGVTADFPHPGFN 78 >2HNT-F nrPDB Length = 105 Score = 120 bits (302), Expect = 6e-28, Method: Composition-based stats. Identities = 27/101 (26%), Positives = 39/101 (38%), Gaps = 9/101 (8%) Query: 172 PPGLMEAKVRVLDPDVCNSSWKGHLTLTMLCTRSG--DSHRRGFCSADSGGPLVCR---- 225 P L + +++ VC S + +T M C + R C DSGGP V + Sbjct: 3 PSVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFN 62 Query: 226 --NRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVRR 264 G+VS+ G C YT V WI V+ + Sbjct: 63 NRWYQMGIVSW-GEGCDRDGKYGFYTHVFRLKKWIQKVIDQ 102 >2WIN-I nrPDB Length = 507 Score = 114 bits (287), Expect = 4e-26, Method: Composition-based stats. Identities = 48/246 (19%), Positives = 83/246 (33%), Gaps = 69/246 (28%) Query: 43 HSRPYMASVRF----GGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVLSTAEP 98 H +P+ A + G C G ++ +V++AAHCF+ D H + + Sbjct: 232 HKQPWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHCFTVDDK--------EHSIKVSVG 283 Query: 99 TQQV-FGIDALTTHPDYH---------PMTHANDICLLRLNGSAVLGPAVGLLRPP---- 144 ++ I+ + HP+Y+ P + D+ L++L G + + P Sbjct: 284 GEKRDLEIEVVLFHPNYNINGKKEAGIPEFYDYDVALIKLKNKLKYGQTIRPICLPCTEG 343 Query: 145 GRRARPPTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDV----------------- 187 RA T C+ EEL P + K + + Sbjct: 344 TTRALRLPPTTTCQ-------QQKEELLPA-QDIKALFVSEEEKKLTRKEVYIKNGDKKG 395 Query: 188 -CN--SSW----------KGHLTLTMLCTRSGDSHRR-GFCSADSGGPLVC----RNRAH 229 C + + +T LCT + C DSGGPL+ R Sbjct: 396 SCERDAQYAPGYDKVKDISEVVTPRFLCTGGVSPYADPNTCRGDSGGPLIVHKRSRFIQV 455 Query: 230 GLVSFS 235 G++S+ Sbjct: 456 GVISWG 461 >1DLE-A nrPDB Length = 298 Score = 113 bits (283), Expect = 9e-26, Method: Composition-based stats. Identities = 48/246 (19%), Positives = 83/246 (33%), Gaps = 69/246 (28%) Query: 43 HSRPYMASVRF----GGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVLSTAEP 98 H +P+ A + G C G ++ +V++AAHCF+ D H + + Sbjct: 25 HKQPWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHCFTVDDK--------EHSIKVSVG 76 Query: 99 TQQV-FGIDALTTHPDYH---------PMTHANDICLLRLNGSAVLGPAVGLLRPP---- 144 ++ I+ + HP+Y+ P + D+ L++L G + + P Sbjct: 77 GEKRDLEIEVVLFHPNYNINGKKEAGIPEFYDYDVALIKLKNKLKYGQTIRPICLPCTEG 136 Query: 145 GRRARPPTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDV----------------- 187 RA T C+ EEL P + K + + Sbjct: 137 TTRALRLPPTTTCQ-------QQKEELLPA-QDIKALFVSEEEKKLTRKEVYIKNGDKKG 188 Query: 188 -CN--SSW----------KGHLTLTMLCTRSGDSHRR-GFCSADSGGPLVC----RNRAH 229 C + + +T LCT + C DSGGPL+ R Sbjct: 189 SCERDAQYAPGYDKVKDISEVVTPRFLCTGGVSPYADPNTCRGDSGGPLIVHKRSRFIQV 248 Query: 230 GLVSFS 235 G++S+ Sbjct: 249 GVISWG 254 >3RU4-E nrPDB Length = 96 Score = 112 bits (280), Expect = 2e-25, Method: Composition-based stats. Identities = 29/100 (29%), Positives = 43/100 (43%), Gaps = 8/100 (8%) Query: 170 ELPPGLMEAKVRVLDPDVCNSSWKGHLTLTMLCTRSGDSHRRGFCSADSGGPLVCR---- 225 P L +A + +L C W + M+C + C DSGGPLVC+ Sbjct: 1 NTPDRLQQASLPLLSNTNCKKYWGTKIKDAMICAGAS---GVSSCMGDSGGPLVCKKNGA 57 Query: 226 NRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVRRS 265 G+VS+ C TP VY +V+A V W+ + + Sbjct: 58 WTLVGIVSWGSSTCSTS-TPGVYARVTALVNWVQQTLAAN 96 >2OK5-A nrPDB Length = 752 Score = 111 bits (279), Expect = 3e-25, Method: Composition-based stats. Identities = 48/246 (19%), Positives = 83/246 (33%), Gaps = 69/246 (28%) Query: 43 HSRPYMASVRF----GGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVLSTAEP 98 H +P+ A + G C G ++ +V++AAHCF+ D H + + Sbjct: 476 HKQPWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHCFTVDDK--------EHSIKVSVG 527 Query: 99 TQQV-FGIDALTTHPDYH---------PMTHANDICLLRLNGSAVLGPAVGLLRPP---- 144 ++ I+ + HP+Y+ P + D+ L++L G + + P Sbjct: 528 GEKRDLEIEVVLFHPNYNINGKKEAGIPEFYDYDVALIKLKNKLKYGQTIRPICLPCTEG 587 Query: 145 GRRARPPTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDV----------------- 187 RA T C+ EEL P + K + + Sbjct: 588 TTRALRLPPTTTCQ-------QQKEELLPA-QDIKALFVSEEEKKLTRKEVYIKNGDKKG 639 Query: 188 -CN--SSW----------KGHLTLTMLCTRSGDSHRR-GFCSADSGGPLVCRNR----AH 229 C + + +T LCT + C DSGGPL+ R Sbjct: 640 SCERDAQYAPGYDKVKDISEVVTPRFLCTGGVSPYADPNTCRGDSGGPLIVHKRSRFIQV 699 Query: 230 GLVSFS 235 G++S+ Sbjct: 700 GVISWG 705 >2JET-C nrPDB Length = 99 Score = 109 bits (274), Expect = 9e-25, Method: Composition-based stats. Identities = 29/100 (29%), Positives = 47/100 (47%), Gaps = 8/100 (8%) Query: 170 ELPPGLMEAKVRVLDPDVCNSSWKGHLTLTMLCTRSGDSHRRGFCSADSGGPLVCR---- 225 + P L +A + ++ C SW +T M C + C DSGGPLVC+ Sbjct: 4 KTPEKLQQAALPIVSEADCKKSWGSKITDVMTCAGAS---GVDSCMGDSGGPLVCQKDGV 60 Query: 226 NRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVRRS 265 G+VS+ C TP VY++V+A + W+ ++ + Sbjct: 61 WTLAGIVSWGSGVCSTS-TPGVYSRVTALMPWVQQILEAN 99 >2I6S-A nrPDB Length = 517 Score = 109 bits (273), Expect = 2e-24, Method: Composition-based stats. Identities = 46/253 (18%), Positives = 78/253 (30%), Gaps = 60/253 (23%) Query: 35 IGGHEVTPHSR---PYMASVRFGGQHHCGGFLLRARWVVSAAHCF-SHRDLRTGLVVLGA 90 +G + P+ +++ Q C G L+ +WV++AAHCF D V +G Sbjct: 230 VGNMSANASDQERTPWHVTIKPKSQETCRGALISDQWVLTAAHCFRDGNDHSLWRVNVG- 288 Query: 91 HVLSTAEPTQQVFGIDALTTHPDYHPMTHAN---------DICLLRLNGSAVLGPAVGLL 141 + F I+ P + N DI LL+L + + Sbjct: 289 ---DPKSQWGKEFLIEKAVISPGFDVFAKKNQGILEFYGDDIALLKLAQKVKMSTHARPI 345 Query: 142 RPPGRRARPPTA----GTRCRVAGWGFVSDFEELPP--------GLMEAKVRV-----LD 184 P G+ C + E L L +K+ + ++ Sbjct: 346 CLPCTMEANLALRRPQGSTC------RDHENELLNKQSVPAHFVALNGSKLNINLKMGVE 399 Query: 185 PDVCNSS-------------WKGHLTLTMLCTRSGDSHRRGFCSADSGGPLVCRNRAH-- 229 C + +T LC+ + + C +SGG + R Sbjct: 400 WTSCAEVVSQEKTMFPNLTDVREVVTDQFLCSGTQED--ESPCKGESGGAVFLERRFRFF 457 Query: 230 --GLVSFS-GLWC 239 GLVS+ C Sbjct: 458 QVGLVSWGLYNPC 470 >1EPT-B nrPDB Length = 82 Score = 109 bits (272), Expect = 2e-24, Method: Composition-based stats. Identities = 27/83 (32%), Positives = 39/83 (46%), Gaps = 3/83 (3%) Query: 84 GLVVLGAHVLSTAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRP 143 V LG H + E +Q + THP+++ T NDI L++L+ A L V + Sbjct: 3 IQVRLGEHNIDVLEGNEQFINAAKIITHPNFNGNTLDNDIMLIKLSSPATLNSRVATVSL 62 Query: 144 PGRRARPPTAGTRCRVAGWGFVS 166 P A AGT C ++GWG Sbjct: 63 PRSCA---AAGTECLISGWGNTK 82 >3F1S-B nrPDB Length = 283 Score = 86.8 bits (214), Expect = 1e-17, Method: Composition-based stats. Identities = 31/160 (19%), Positives = 54/160 (33%), Gaps = 10/160 (6%) Query: 46 PYMASV-RFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVLSTAEPTQQVFG 104 P+ + G+ CGG ++R +V++ A C R V + + Sbjct: 65 PWQVKLTNSEGKDFCGGVIIRENFVLTTAKC--SLLHRNITV---KTYFNRTSQDPLMIK 119 Query: 105 IDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARP--PTAGTRCRVAGW 162 I + H Y ND+ LL L A + P + TR ++GW Sbjct: 120 ITHVHVHMRYDADAGENDLSLLELEWPIQCPGAGLPVCTPEKDFAEHLLIPRTRGLLSGW 179 Query: 163 GFVSDFEELPPGLMEAKVRVLDPDVCNSSWKGHLTLTMLC 202 + +L L V +++ + C +T C Sbjct: 180 --ARNGTDLGNSLTTRPVTLVEGEECGQVLNVTVTTRTYC 217 >3H5C-B nrPDB Length = 317 Score = 84.9 bits (209), Expect = 4e-17, Method: Composition-based stats. Identities = 31/160 (19%), Positives = 54/160 (33%), Gaps = 10/160 (6%) Query: 46 PYMASV-RFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVLSTAEPTQQVFG 104 P+ + G+ CGG ++R +V++ A C R V + + Sbjct: 106 PWQVKLTNSEGKDFCGGVIIRENFVLTTAKC--SLLHRNITV---KTYFNRTSQDPLMIK 160 Query: 105 IDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARP--PTAGTRCRVAGW 162 I + H Y ND+ LL L A + P + TR ++GW Sbjct: 161 ITHVHVHMRYDADAGENDLSLLELEWPIQCPGAGLPVCTPEKDFAEHLLIPRTRGLLSGW 220 Query: 163 GFVSDFEELPPGLMEAKVRVLDPDVCNSSWKGHLTLTMLC 202 + +L L V +++ + C +T C Sbjct: 221 --ARNGTDLGNSLTTRPVTLVEGEECGQVLNVTVTTRTYC 258 >2HNT-E nrPDB Length = 81 Score = 81.4 bits (200), Expect = 4e-16, Method: Composition-based stats. Identities = 16/72 (22%), Positives = 30/72 (41%), Gaps = 3/72 (4%) Query: 100 QQVFGIDALTTHPDYHP-MTHANDICLLRLNGSAVLGPAVGLLRPPGRRA--RPPTAGTR 156 +++ ++ + HP Y+ DI L++L + + P R AG + Sbjct: 3 EKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYK 62 Query: 157 CRVAGWGFVSDF 168 RV GWG + + Sbjct: 63 GRVTGWGNLKET 74 >2HNT-C nrPDB Length = 70 Score = 76.4 bits (187), Expect = 1e-14, Method: Composition-based stats. Identities = 17/70 (24%), Positives = 28/70 (40%), Gaps = 8/70 (11%) Query: 34 IIGGHEVTPHSRPYMASVRFGG--QHHCGGFLLRARWVVSAAHCFSHRDL------RTGL 85 I+ G + P+ + + CG L+ RWV++AAHC + L Sbjct: 1 IVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLL 60 Query: 86 VVLGAHVLST 95 V +G H + Sbjct: 61 VRIGKHSRTR 70 >1P3E-A nrPDB Length = 215 Score = 49.1 bits (116), Expect = 2e-06, Method: Composition-based stats. Identities = 24/124 (19%), Positives = 47/124 (37%), Gaps = 16/124 (12%) Query: 46 PY--MASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTG----LVVLGAHVLSTAEPT 99 PY +A + FGG C G L+ +++ HC + R+ V G + + + Sbjct: 18 PYNSIAYITFGGSS-CTGTLIAPNKILTNGHCVYNTASRSYSAKGSVYPGMNDSTAVNGS 76 Query: 100 QQVFGIDALTTHPDY-HPMTHANDICLLRLNGSAVLGPAVGLLRPPGRRARPPTAGTRCR 158 + Y + D +++ + +G VG R+ T GT + Sbjct: 77 A---NMTEFYVPSGYINTGASQYDFAVIKTDT--NIGNTVGYRS--IRQVTNLT-GTTIK 128 Query: 159 VAGW 162 ++G+ Sbjct: 129 ISGY 132 >2EA3-A nrPDB Length = 189 Score = 34.1 bits (77), Expect = 0.076, Method: Composition-based stats. Identities = 11/29 (37%), Positives = 14/29 (48%) Query: 216 ADSGGPLVCRNRAHGLVSFSGLWCGDPKT 244 DSGG L+ N+A G+ S C T Sbjct: 135 GDSGGSLLAGNQAQGVTSGGSGNCRTGGT 163 >1DUE-A nrPDB Length = 242 Score = 33.3 bits (75), Expect = 0.11, Method: Composition-based stats. Identities = 17/119 (14%), Positives = 35/119 (29%), Gaps = 13/119 (10%) Query: 51 VRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVLSTAEPTQQV----FGID 106 V GQ G L+ V++ H + V + + + + + Sbjct: 49 VFVKGQTSATGVLIGKNTVLTNRHIAKFANGDPSKVSFRPSINTDDNGNTETPYGEYEVK 108 Query: 107 ALTTHPDYHPMTHANDICLLRLNGS---AVLGPAVGLLRPPGRRARPPTAGTRCRVAGW 162 + P D+ L+RL LG + + + G + + G+ Sbjct: 109 EILQEP----FGAGVDLALIRLKPDQNGVSLGDKISPAK--IGTSNDLKDGDKLELIGY 161 >2PFE-A nrPDB Length = 186 Score = 32.9 bits (74), Expect = 0.16, Method: Composition-based stats. Identities = 11/36 (30%), Positives = 16/36 (44%), Gaps = 2/36 (5%) Query: 210 RRGFCS--ADSGGPLVCRNRAHGLVSFSGLWCGDPK 243 R C+ DSGGP + ++A G+ S C Sbjct: 130 RTTACAEGGDSGGPWLTGSQAQGVTSGGTGDCRSGG 165 >2OUA-A nrPDB Length = 188 Score = 32.9 bits (74), Expect = 0.18, Method: Composition-based stats. Identities = 11/37 (29%), Positives = 15/37 (40%), Gaps = 2/37 (5%) Query: 210 RRGFCS--ADSGGPLVCRNRAHGLVSFSGLWCGDPKT 244 R C+ DSGG + +A G+ S C T Sbjct: 133 RTSVCAEPGDSGGSFISGTQAQGVTSGGSGNCRTGGT 169 >2HRV-A nrPDB Length = 142 Score = 31.7 bits (71), Expect = 0.32, Method: Composition-based stats. Identities = 12/50 (24%), Positives = 21/50 (42%), Gaps = 8/50 (16%) Query: 189 NSSWKGHLTLTMLCTRSGDSHRRGFCS-ADSGGPLVCRNRAHGLVSFSGL 237 + + H+ +L G C D GG L+C++ G+V+ G Sbjct: 83 SEYYPKHIQYNLLI-------GEGPCEPGDCGGKLLCKHGVIGIVTAGGD 125 >3LT3-A nrPDB Length = 217 Score = 31.4 bits (70), Expect = 0.43, Method: Composition-based stats. Identities = 36/173 (20%), Positives = 61/173 (35%), Gaps = 37/173 (21%) Query: 61 GFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVLSTAEPTQQVFGIDALTTHPDYHPMTHA 120 GF++ V++ AH VV G++ ++ + +A Y P Sbjct: 42 GFVISPDRVMTNAH-----------VVAGSNNVTVYAGDKPF---EATVV--SYDPSV-- 83 Query: 121 NDICLLRLNGSAVLGPAVGLLRPPGRRARPPTAGTRCRVAGWGFVSDFEELPPGLMEAKV 180 D+ +L P A P G V G+ +F P + EA + Sbjct: 84 -DVAIL--------AVPHLPPPPLVFAAEPAKTGADVVVLGYPGGGNFTATPARIREA-I 133 Query: 181 RVLDPDVCNSSWKGHLTLTMLCTRSGDSHRRGFCSADSGGPLV-CRNRAHGLV 232 R+ PD+ + +T R + R D+GGPL+ + G+V Sbjct: 134 RLSGPDI----YGDPEPVT----RDVYTIRADVEQGDAGGPLIDLNGQVLGVV 178 >4FVB-A nrPDB Length = 152 Score = 31.4 bits (70), Expect = 0.47, Method: Composition-based stats. Identities = 9/23 (39%), Positives = 13/23 (56%) Query: 216 ADSGGPLVCRNRAHGLVSFSGLW 238 D+GG L C++ G+VS G Sbjct: 110 GDAGGILRCQHGVVGIVSTGGNG 132 >3W95-A nrPDB Length = 171 Score = 31.4 bits (70), Expect = 0.47, Method: Composition-based stats. Identities = 9/23 (39%), Positives = 13/23 (56%) Query: 216 ADSGGPLVCRNRAHGLVSFSGLW 238 D+GG L C++ G+VS G Sbjct: 129 GDAGGILRCQHGVVGIVSTGGNG 151 >2M5T-A nrPDB Length = 142 Score = 31.0 bits (69), Expect = 0.64, Method: Composition-based stats. Identities = 12/51 (23%), Positives = 21/51 (41%), Gaps = 8/51 (15%) Query: 189 NSSWKGHLTLTMLCTRSGDSHRRGFCS-ADSGGPLVCRNRAHGLVSFSGLW 238 + H+ +L G C D+GG L+CR+ G+++ G Sbjct: 82 TQYYPKHIQYNLL-------IGEGPCVPGDAGGKLLCRHGVIGIITAGGDG 125 >2SFA-A nrPDB Length = 191 Score = 30.6 bits (68), Expect = 0.73, Method: Composition-based stats. Identities = 11/29 (37%), Positives = 12/29 (41%) Query: 216 ADSGGPLVCRNRAHGLVSFSGLWCGDPKT 244 DSGG L + A GL S C T Sbjct: 145 GDSGGALFAGSTALGLTSGGSGNCRTGGT 173 >4V1Y-A nrPDB Length = 494 Score = 29.4 bits (65), Expect = 1.9, Method: Composition-based stats. Identities = 18/63 (28%), Positives = 22/63 (34%), Gaps = 10/63 (15%) Query: 64 LRARWVVSAAHCFSHRDLRTGLVVLGAHVLSTAEPTQQVFGIDALTTHPDY-HPMTHAND 122 L WV H R +V LG H S P +V P + + TH N Sbjct: 41 LGDSWV----HVQDGR-----IVALGVHAESVPPPADRVIDARGKVVLPGFINAHTHVNQ 91 Query: 123 ICL 125 I L Sbjct: 92 ILL 94 >4NSY-A nrPDB Length = 275 Score = 29.0 bits (64), Expect = 2.1, Method: Composition-based stats. Identities = 13/67 (19%), Positives = 24/67 (35%), Gaps = 16/67 (23%) Query: 15 VATALMLPVKPPAGSWGAQIIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRAR------W 68 V+ + + V P G+ +I +A+ G C G L+ + Sbjct: 2 VSGSCNIDVVCPEGNGHRDVI----------RSVAAYSKQGTMWCTGSLVNNSANDKKMY 51 Query: 69 VVSAAHC 75 ++A HC Sbjct: 52 FLTANHC 58 >2SGA-A nrPDB Length = 181 Score = 29.0 bits (64), Expect = 2.1, Method: Composition-based stats. Identities = 11/29 (37%), Positives = 12/29 (41%) Query: 216 ADSGGPLVCRNRAHGLVSFSGLWCGDPKT 244 DSGG L + A GL S C T Sbjct: 135 GDSGGSLFAGSTALGLTSGGSGNCRTGGT 163 >1HPG-A nrPDB Length = 187 Score = 28.7 bits (63), Expect = 2.8, Method: Composition-based stats. Identities = 15/58 (25%), Positives = 19/58 (32%), Gaps = 8/58 (13%) Query: 189 NSSWKGHLTLTMLCTRSGDS-----HRRGFCS--ADSGGPLVCRNRAHGLVSFSGLWC 239 G +T + GD R CS DSGG + A G+ S C Sbjct: 107 TKVTSGTVTAVNVTVNYGDGPVYNMVRTTACSAGGDSGGAHFAGSVALGIHS-GSSGC 163 >4XZB-A nrPDB Length = 314 Score = 28.3 bits (62), Expect = 4.4, Method: Composition-based stats. Identities = 11/37 (29%), Positives = 14/37 (37%) Query: 143 PPGRRARPPTAGTRCRVAGWGFVSDFEELPPGLMEAK 179 R AGT V+ WG + P L EA+ Sbjct: 213 LRDRVDAALQAGTPVFVSEWGTSDASGDGGPYLEEAE 249 >4B6E-A nrPDB Length = 683 Score = 27.5 bits (60), Expect = 6.9, Method: Composition-based stats. Identities = 10/29 (34%), Positives = 12/29 (41%), Gaps = 3/29 (10%) Query: 215 SADSGGPLVC-RNRAHGLVSFSGLWCGDP 242 SGGPL+C A G+ F C Sbjct: 171 KGSSGGPLLCPSGHAVGI--FRAAVCTRG 197 >4NWK-A nrPDB Length = 219 Score = 27.1 bits (59), Expect = 8.0, Method: Composition-based stats. Identities = 10/29 (34%), Positives = 12/29 (41%), Gaps = 3/29 (10%) Query: 215 SADSGGPLVCR-NRAHGLVSFSGLWCGDP 242 SGGPL+C A G+ F C Sbjct: 151 KGSSGGPLLCPAGHAVGI--FRAAVCTRG 177 >6C2N-A nrPDB Length = 203 Score = 27.1 bits (59), Expect = 8.4, Method: Composition-based stats. Identities = 8/18 (44%), Positives = 10/18 (55%), Gaps = 1/18 (5%) Query: 215 SADSGGPLVCR-NRAHGL 231 SGGPL+C A G+ Sbjct: 157 KGSSGGPLLCPAGHAVGI 174 >6FE6-A nrPDB Length = 165 Score = 27.1 bits (59), Expect = 9.4, Method: Composition-based stats. Identities = 8/18 (44%), Positives = 10/18 (55%), Gaps = 1/18 (5%) Query: 215 SADSGGPLVC-RNRAHGL 231 SGGPL+C A G+ Sbjct: 115 KGSSGGPLLCPSGHAVGI 132 >4U01-A nrPDB Length = 203 Score = 27.1 bits (59), Expect = 9.6, Method: Composition-based stats. Identities = 8/18 (44%), Positives = 10/18 (55%), Gaps = 1/18 (5%) Query: 215 SADSGGPLVC-RNRAHGL 231 SGGPL+C A G+ Sbjct: 137 KGSSGGPLLCPSGHAVGI 154 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.309 0.155 0.554 Lambda K H 0.267 0.0480 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 13,737,289 Number of Sequences: 36641 Number of extensions: 621856 Number of successful extensions: 2868 Number of sequences better than 10.0: 186 Number of HSP's better than 10.0 without gapping: 313 Number of HSP's successfully gapped in prelim test: 42 Number of HSP's that attempted gapping in prelim test: 1277 Number of HSP's gapped (non-prelim): 381 length of query: 283 length of database: 10,336,785 effective HSP length: 96 effective length of query: 187 effective length of database: 6,819,249 effective search space: 1275199563 effective search space used: 1275199563 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.0 bits) S2: 59 (27.1 bits)