BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q6P179 (960 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 3SE6-A nrPDB 1996 0.0 3QNF-A nrPDB 979 0.0 5C97-A nrPDB 772 0.0 4KXA-A nrPDB 530 e-150 5LG6-A nrPDB 469 e-132 5LHD-A nrPDB 461 e-130 3RJO-A nrPDB 386 e-107 4WZ9-A nrPDB 375 e-104 1Z1W-A nrPDB 275 5e-74 5DLL-A nrPDB 119 5e-27 5Y1X-A nrPDB 115 1e-25 4QHP-A nrPDB 100 4e-21 4Q4I-A nrPDB 98 2e-20 3CIA-A nrPDB 88 2e-17 2XPY-A nrPDB 84 2e-16 4GAA-A nrPDB 81 2e-15 5ZI5-A nrPDB 80 5e-15 5FWQ-A nrPDB 79 1e-14 3BIC-A nrPDB 35 0.11 4ZXO-A nrPDB 33 0.89 2B3Y-A nrPDB 30 4.8 2DG8-A nrPDB 30 5.1 1PBY-A nrPDB 30 6.8 >3SE6-A nrPDB Length = 967 Score = 1996 bits (5171), Expect = 0.0, Method: Compositional matrix adjust. Identities = 958/960 (99%), Positives = 958/960 (99%) Query: 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGE 60 M HSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGE Sbjct: 1 MVHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGE 60 Query: 61 RFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNA 120 RFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNA Sbjct: 61 RFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNA 120 Query: 121 TLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFY 180 TLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFY Sbjct: 121 TLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFY 180 Query: 181 KSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVK 240 KSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVK Sbjct: 181 KSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVK 240 Query: 241 TIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYAL 300 TIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYAL Sbjct: 241 TIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYAL 300 Query: 301 QASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASD 360 QASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASD Sbjct: 301 QASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASD 360 Query: 361 KLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNV 420 KLWVTRVIAHELAHQWFGNLVTMEWWNDIWL EGFAKYMELIAVNATYPELQFDDYFLNV Sbjct: 361 KLWVTRVIAHELAHQWFGNLVTMEWWNDIWLNEGFAKYMELIAVNATYPELQFDDYFLNV 420 Query: 421 CFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQ 480 CFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQ Sbjct: 421 CFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQ 480 Query: 481 YLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTT 540 YLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTT Sbjct: 481 YLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTT 540 Query: 541 WTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVI 600 WTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVI Sbjct: 541 WTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVI 600 Query: 601 HRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRV 660 HRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRV Sbjct: 601 HRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRV 660 Query: 661 GLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISE 720 GLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISE Sbjct: 661 GLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISE 720 Query: 721 NLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMES 780 NLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMES Sbjct: 721 NLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMES 780 Query: 781 SGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKL 840 SGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKL Sbjct: 781 SGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKL 840 Query: 841 IELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISG 900 IELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISG Sbjct: 841 IELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISG 900 Query: 901 TTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 960 TTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT Sbjct: 901 TTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 960 >3QNF-A nrPDB Length = 954 Score = 979 bits (2532), Expect = 0.0, Method: Compositional matrix adjust. Identities = 475/920 (51%), Positives = 640/920 (69%), Gaps = 15/920 (1%) Query: 39 SVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIE 98 S PS TE A P ++G FPW ++RLP VIP+HYDL +H NLT+L F + K+E Sbjct: 33 STPSWCQSTE---ASPKRSDGTPFPWNKIRLPEYVIPVHYDLLIHANLTTLTFWGTTKVE 89 Query: 99 VLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTP 158 + S T IILHS L+I+ ATL+ R + + L+VL +P EQIALL PE L Sbjct: 90 ITASQPTSTIILHSHHLQISRATLRKGAGERLSE--EPLQVLEHPRQEQIALLAPEPLLV 147 Query: 159 HLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKA 218 L Y V + + L + F GFYKSTYRT GE RILA T FEPT ARMAFPCFDEP FKA Sbjct: 148 GLPYTVVIHYAGNLSETFHGFYKSTYRTKEGELRILASTQFEPTAARMAFPCFDEPAFKA 207 Query: 219 NFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFT 278 +FSIKIRRE RH+A+SNMP VK++ + GL+EDHF+ TVKMSTYLVA+I+ DF S+S T Sbjct: 208 SFSIKIRREPRHLAISNMPLVKSVTVAEGLIEDHFDVTVKMSTYLVAFIISDFESVSKIT 267 Query: 279 SSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMEN 338 SGVKVS+YA PDK NQ YAL A++ LL+FYE YF I YPL K DL AIPDF GAMEN Sbjct: 268 KSGVKVSVYAVPDKINQADYALDAAVTLLEFYEDYFSIPYPLPKQDLAAIPDFQSGAMEN 327 Query: 339 WGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKY 398 WGL TYRE++LLFD + SSAS KL +T +AHELAHQWFGNLVTMEWWND+WL EGFAK+ Sbjct: 328 WGLTTYRESALLFDAEKSSASSKLGITMTVAHELAHQWFGNLVTMEWWNDLWLNEGFAKF 387 Query: 399 MELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKG 458 ME ++V+ T+PEL+ DYF CF+ + D+LNSS P+S P E P QI+EMFD+VSY+KG Sbjct: 388 MEFVSVSVTHPELKVGDYFFGKCFDAMEVDALNSSHPVSTPVENPAQIREMFDDVSYDKG 447 Query: 459 ACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSG--GVCHS 516 ACILNML+++L + F+ GI+QYL+K SY+N KN+DLW S+++ C +D G G C Sbjct: 448 ACILNMLREYLSADAFKSGIVQYLQKHSYKNTKNEDLWDSMASIC-PTDGVKGMDGFCSR 506 Query: 517 DPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPE 576 + +S+ + E +VK MM TWTLQKG PL+ + G ++ ++QE +++G Sbjct: 507 S-QHSSSSSHWHQEGVDVKTMMNTWTLQKGFPLITITVRGRNVHMKQEHYMKGSDG---- 561 Query: 577 WRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYE 636 A YLWH+PLT+ TS S+++HR +LK+KTD L LPE+ W+KFNV NGYYIVHYE Sbjct: 562 --APDTGYLWHVPLTFITSKSDMVHRFLLKTKTDVLILPEEVEWIKFNVGMNGYYIVHYE 619 Query: 637 GHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPAL 696 GWD L L HT + DR LI++ FQLV G+L+++KALD++ YL+HET + Sbjct: 620 DDGWDSLTGLLKGTHTAVSSNDRASLINNAFQLVSIGKLSIEKALDLSLYLKHETEIMPV 679 Query: 697 LEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLK 756 +GL+ L Y +M++R+++++ K +L++ + +ID+Q+W+D+GSV +RMLRS LL Sbjct: 680 FQGLNELIPMYKLMEKRDMNEVETQFKAFLIRLLRDLIDKQTWTDEGSVSERMLRSQLLL 739 Query: 757 LACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSM 816 LAC N+ PC+Q+A F +W ES+G L++P DV V++VGAQ+T GW++L +Y+ S+ Sbjct: 740 LACVHNYQPCVQRAEGYFRKWKESNGNLSLPVDVTLAVFAVGAQSTEGWDFLYSKYQFSL 799 Query: 817 SSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFV 876 SS E+++I +AL ++++EKL L++ +G IKTQ +L I R P G LAW F+ Sbjct: 800 SSTEKSQIEFALCRTQNKEKLQWLLDESFKGDKIKTQEFPQILTLIGRNPVGYPLAWQFL 859 Query: 877 RENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLE 936 R+NW L++KF+LGS I ++ GTT FS++ +L+EVK FF SL+ GS L Q +E Sbjct: 860 RKNWNKLVQKFELGSSSIAHMVMGTTNQFSTRTRLEEVKGFFSSLKENGSQLRCVQQTIE 919 Query: 937 TITKNIKWLEKNLPTLRTWL 956 TI +NI W++KN +R WL Sbjct: 920 TIEENIGWMDKNFDKIRVWL 939 >5C97-A nrPDB Length = 912 Score = 772 bits (1993), Expect = 0.0, Method: Compositional matrix adjust. Identities = 401/908 (44%), Positives = 561/908 (61%), Gaps = 36/908 (3%) Query: 56 ATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDL 115 ATNG+ FPW ++RLP+ V+PL Y+L +HPNLTS+ F S I V T IILHS Sbjct: 32 ATNGKLFPWAQIRLPTAVVPLRYELSLHPNLTSMTFRGSVTISVQALQVTWNIILHSTGH 91 Query: 116 EITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDG 175 I+ T S S+ K+ ++L Y H QIA++ PE L Y + +++ A + Sbjct: 92 NISRVTFMSAVSSQ----EKQAEILEYAYHGQIAIVAPEALLAGHNYTLKIEYSANISSS 147 Query: 176 FEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSN 235 + GFY +Y E + A T FEP AR AFPCFDEP FKA F IKI R+ ++ ALSN Sbjct: 148 YYGFYGFSYTDESNEKKYFAATQFEPLAARSAFPCFDEPAFKATFIIKIIRDEQYTALSN 207 Query: 236 MPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQ 295 MPK ++ L+ GL++D F +VKMSTYLVA+IV + +LS +G VSIYA P+K Q Sbjct: 208 MPKKSSVVLDDGLVQDEFSESVKMSTYLVAFIVGEMKNLSQ-DVNGTLVSIYAVPEKIGQ 266 Query: 296 THYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKT 355 HYAL+ ++KLL+F++ YF+I YPL KLDL+AIPDF GAMENWGL+T+RE +LL+D T Sbjct: 267 VHYALETTVKLLEFFQNYFEIQYPLKKLDLVAIPDFEAGAMENWGLLTFREETLLYDSNT 326 Query: 356 SSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDD 415 SS +D+ VT++IAHELAHQWFGNLVTM+WWND+WL EGFA +ME ++ + EL + Sbjct: 327 SSMADRKLVTKIIAHELAHQWFGNLVTMKWWNDLWLNEGFATFMEYFSLEKIFKELSSYE 386 Query: 416 YFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQ 475 FL+ F+ + KDSLNSS PIS ++ QI+EMFD +SY KG+ +L MLK +L E+ FQ Sbjct: 387 DFLDARFKTMKKDSLNSSHPISSSVQSSEQIEEMFDSLSYFKGSSLLLMLKTYLSEDVFQ 446 Query: 476 KGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVK 535 ++ YL SY + ++DDLW S + ++T+ L +VK Sbjct: 447 HAVVLYLHNHSYASIQSDDLWDSFN------------------EVTNQTL-------DVK 481 Query: 536 EMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTS 595 MM TWTLQKG PL+ V++ G L +QQERF + PE + YLWHIPL+Y T Sbjct: 482 RMMKTWTLQKGFPLVTVQKKGKELFIQQERFFLNM---KPEIQPSDTSYLWHIPLSYVTE 538 Query: 596 SSNVIHRH---ILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHT 652 N +L K+ ++L E+ WVK N++ NGYYIVHY W+ LI QL N Sbjct: 539 GRNYSKYQSVSLLDKKSGVINLTEEVLWVKVNINMNGYYIVHYADDDWEALIHQLKINPY 598 Query: 653 LLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDR 712 +L KDR LI+++F+L G G++ L +A D+ YL +E + + E L + Y+++++ Sbjct: 599 VLSDKDRANLINNIFELAGLGKVPLKRAFDLINYLGNENHTAPITEALFQTDLIYNLLEK 658 Query: 713 RNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAE 772 D++ L + + + I +Q+W+D+G+ R LRSALL+ AC N C A + Sbjct: 659 LGYMDLASRLVTRVFKLLQNQIQQQTWTDEGTPSMRELRSALLEFACTHNLGNCSTTAMK 718 Query: 773 LFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSK 832 LF WM S+G ++PTDV+ V+ VGA+T GW++LL +Y S AE+NKIL AL++S+ Sbjct: 719 LFDDWMASNGTQSLPTDVMTTVFKVGAKTDKGWSFLLGKYISIGSEAEKNKILEALASSE 778 Query: 833 HQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSY 892 KL L++ + G +TQ L+ ++ + R G LAWDFV+ENW L++KF LGSY Sbjct: 779 DVRKLYWLMKSSLNGDNFRTQKLSFIIRTVGRHFPGHLLAWDFVKENWNKLVQKFPLGSY 838 Query: 893 DIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTL 952 I+ I++G+T FS+K L EV+ FFE+ L Q LE I NI+W+EKNL +L Sbjct: 839 TIQNIVAGSTYLFSTKTHLSEVQAFFENQSEATFRLRCVQEALEVIQLNIQWMEKNLKSL 898 Query: 953 RTWLMVNT 960 WL T Sbjct: 899 TWWLRTET 906 >4KXA-A nrPDB Length = 888 Score = 530 bits (1365), Expect = e-150, Method: Compositional matrix adjust. Identities = 315/919 (34%), Positives = 494/919 (53%), Gaps = 64/919 (6%) Query: 56 ATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDL 115 A+ E W+ RLP V P+HYDL V P L + + I + +S T+++ LH ++ Sbjct: 5 ASEDESGQWKNFRLPDFVNPVHYDLHVKPLLEEDTYTGTVSISINLSAPTRYLWLHLRET 64 Query: 116 EITNATLQSEEDSRYMKP-GKELKV---LSYPAHEQIALLVPEKLTPHLK---YYVAMDF 168 IT +P G +++V Y E + + E+LTP Y + M+F Sbjct: 65 RITRL-------PELKRPSGDQVQVRRCFEYKKQEYVVVEAEEELTPSSGDGLYLLTMEF 117 Query: 169 QAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRES 228 L GFY++TY T G + +A TD EPT AR +FPCFDEP KA ++I I Sbjct: 118 AGWLNGSLVGFYRTTY-TENGRVKSIAATDHEPTDARKSFPCFDEPNKKATYTISITHPK 176 Query: 229 RHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYA 288 + ALSNMP K ++ FE +V MSTYLV + V F S+ ++SG ++IY Sbjct: 177 EYGALSNMPVAKEESVDDKWTRTTFEKSVPMSTYLVCFAVHQFDSVKRISNSGKPLTIYV 236 Query: 289 SPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETS 348 P++++ YA + + D++E+YF + Y L KLD IAIPDF GAMENWGLITYRET+ Sbjct: 237 QPEQKHTAEYAANITKSVFDYFEEYFAMNYSLPKLDKIAIPDFGTGAMENWGLITYRETN 296 Query: 349 LLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATY 408 LL+DPK S++S++ V V+AHEL HQWFGN+VTM+WW D+WL EGFA + E + VN Sbjct: 297 LLYDPKESASSNQQRVATVVAHELVHQWFGNIVTMDWWEDLWLNEGFASFFEFLGVNHAE 356 Query: 409 PELQF-DDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKD 467 + Q D L V DSL SS PI TP +I +FD +SY+KG+ IL ML+D Sbjct: 357 TDWQMRDQMLLEDVLPVQEDDSLMSSHPIIVTVTTPDEITSVFDGISYSKGSSILRMLED 416 Query: 468 FLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAF 527 ++ E FQKG YL+K+ ++NAK D W++L + Sbjct: 417 WIKPENFQKGCQMYLEKYQFKNAKTSDFWAALEEAS------------------------ 452 Query: 528 LGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWH 587 VKE+M TWT Q G P+L V +G + Q+RFL + +P Y W+ Sbjct: 453 ---RLPVKEVMDTWTRQMGYPVLNV--NGVK-NITQKRFLLDP-RANPSQPPSDLGYTWN 505 Query: 588 IPLTYS---TSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLI 644 IP+ ++ +SS + +R + T P +++K N D G+Y V+YE WD + Sbjct: 506 IPVKWTEDNITSSVLFNRSEKEGITLNSSNPSGNAFLKINPDHIGFYRVNYEVATWDSIA 565 Query: 645 TQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSS---PALLEGLS 701 T L+ NH DR LI D F L A L AL++T YL+ E + ++ ++ Sbjct: 566 TALSLNHKTFSSADRASLIDDAFALARAQLLDYKVALNLTKYLKREENFLPWQRVISAVT 625 Query: 702 YLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDL 761 Y+ S + + ++ ++ Y KP+ D W+D G ++LRS++L AC + Sbjct: 626 YIISMFE-----DDKELYPMIEEYFQGQVKPIADSLGWNDAGDHVTKLLRSSVLGFACKM 680 Query: 762 NHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAG---WNYLLEQYELSMSS 818 + A+ LF QW+ +G +++P ++ +VY G Q + WNY LEQY+ + + Sbjct: 681 GDREALNNASSLFEQWL--NGTVSLPVNLRLLVYRYGMQNSGNEISWNYTLEQYQKTSLA 738 Query: 819 AEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRE 878 E+ K+LY L++ K+ L + ++L + +IKTQ++ ++ I+ G+ +AW++++ Sbjct: 739 QEKEKLLYGLASVKNVTLLSRYLDLLKDTNLIKTQDVFTVIRYISYNSYGKNMAWNWIQL 798 Query: 879 NWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETI 938 NW +L+ ++ L + ++ I++ F+++ +L +++ FF G+ + VLET+ Sbjct: 799 NWDYLVNRYTLNNRNLGRIVT-IAEPFNTELQLWQMESFFAKYPQAGAGEKPREQVLETV 857 Query: 939 TKNIKWLEKNLPTLRTWLM 957 NI+WL+++ T+R W Sbjct: 858 KNNIEWLKQHRNTIREWFF 876 >5LG6-A nrPDB Length = 968 Score = 469 bits (1208), Expect = e-132, Method: Compositional matrix adjust. Identities = 311/932 (33%), Positives = 474/932 (50%), Gaps = 74/932 (7%) Query: 63 PWQELRLPSVVIPLHYDLFVHPNLT-SLD----FVASEKIEVLVSNATQFIILHSKDLEI 117 PW RLP+ ++P Y++ + P LT + D F + + T II+HSK L Sbjct: 48 PWNRYRLPTTLLPDSYNVTLRPYLTPNADGLYIFKGKSIVRFICQEPTDVIIIHSKKLNY 107 Query: 118 TN----ATLQSEEDSRYMKPGK-ELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKL 172 T L+ DS+ + + EL L+ E + + + L P Y + +FQ +L Sbjct: 108 TTQGHMVVLRGVGDSQVPEIDRTELVELT----EYLVVHLKGSLQPGHMYEMESEFQGEL 163 Query: 173 GDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIA 232 D GFY+S Y G ++LA T + T AR +FPCFDEP KA F+I + + A Sbjct: 164 ADDLAGFYRSEYME-GNVKKVLATTQMQSTDARKSFPCFDEPAMKATFNITLIHPNNLTA 222 Query: 233 LSNMPKVKTIELEGGLLED------HFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSI 286 LSNMP + L ED FETT MSTYL+AYIV +F S++ +GV + I Sbjct: 223 LSNMPPKGS---STPLAEDPNWSVTEFETTPVMSTYLLAYIVSEFQSVNETAQNGVLIRI 279 Query: 287 YASPDKRNQTH--YALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITY 344 +A P+ + H YAL + +L+F+ +++ YPL K D IA+PDF GAMENWGL+TY Sbjct: 280 WARPNAIAEGHGMYALNVTGPILNFFANHYNTSYPLPKSDQIALPDFNAGAMENWGLVTY 339 Query: 345 RETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAV 404 RE +LLFDP++SS S+K V VIAHELAHQWFGNLVT+ WWND+WL EGFA Y+E + Sbjct: 340 RENALLFDPQSSSISNKERVVTVIAHELAHQWFGNLVTLAWWNDLWLNEGFASYVEYLGA 399 Query: 405 NATYPELQFDDYFL-NVCFEVITKDSLNSSRPISKPAE---TPTQIQEMFDEVSYNKGAC 460 + P D + + V+ D+L SS P++ PAE TP QI EMFD +SY+KGA Sbjct: 400 DHAEPTWNLKDLIVPGDVYRVMAVDALASSHPLTTPAEEVNTPAQISEMFDSISYSKGAS 459 Query: 461 ILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKM 520 ++ ML +FL E+ F++G+ YL F+Y+N DLW L + Sbjct: 460 VIRMLSNFLTEDLFKEGLASYLHAFAYQNTTYLDLWEHLQKAV--------------DAQ 505 Query: 521 TSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRAL 580 TS L V+ +M WTLQ G P++ V D + + Q+ FL + E R+ Sbjct: 506 TSIRLP-----DTVRAIMDRWTLQMGFPVITV--DTKTGNISQKHFL--LDSESNVTRSS 556 Query: 581 QERYLWHIPLTYSTSSSNVIHRH-----ILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHY 635 YLW +P+ S+ + V+ H + +++ D WV NV+ GY+ V+Y Sbjct: 557 AFDYLWIVPI--SSIKNGVMQDHYWLRDVSQAQNDLFKTASD-DWVLLNVNVTGYFQVNY 613 Query: 636 EGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPA 695 + W + QL N +++ +R +I+D F L A + + ALD T +L E Sbjct: 614 DEDNWRMIQHQLQTNLSVIPVINRAQVIYDSFNLATAHMVPVTLALDNTLFLNGEKEYMP 673 Query: 696 LLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDR-----QSWSDKG-SVWDRM 749 LS L F M DR S++ +K+YL + +P+ ++W+++ ++ D+ Sbjct: 674 WQAALSSLSYFSLMFDR---SEVYGPMKKYLRKQVEPLFQHFETLTKNWTERPENLMDQY 730 Query: 750 LRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVY--SVGAQTTAGWNY 807 + AC C A LF QWM I ++ +Y ++ W++ Sbjct: 731 SEINAISTACSNGLPQCENLAKTLFDQWMSDPENNPIHPNLRSTIYCNAIAQGGQDQWDF 790 Query: 808 LLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPK 867 Q + + E +K+ AL+ S L + + + +I+ Q+ + +++IA Sbjct: 791 AWGQLQQAQLVNEADKLRSALACSNEVWLLNRYLGYTLNPDLIRKQDATSTINSIASNVI 850 Query: 868 GQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLE--AQG 925 GQ LAWDFV+ NW L + + GS+ +I G T FSS+ +LQ+++ F ++ G Sbjct: 851 GQPLAWDFVQSNWKKLFQDYGGGSFSFSNLIQGVTRRFSSEFELQQLEQFKKNNMDVGFG 910 Query: 926 SHLDIFQTVLETITKNIKWLEKNLPTLRTWLM 957 S + LE NIKW+++N + W + Sbjct: 911 SGTRALEQALEKTKANIKWVKENKEVVLNWFI 942 >5LHD-A nrPDB Length = 950 Score = 461 bits (1186), Expect = e-130, Method: Compositional matrix adjust. Identities = 312/934 (33%), Positives = 466/934 (49%), Gaps = 75/934 (8%) Query: 64 WQELRLPSVVIPLHYDLFVHPNLTSLD-----FVASEKIEVLVSNATQFIILHSKDLEIT 118 W RLP+ + P Y + + P LT D F S + AT II+HSK L Sbjct: 54 WNRYRLPNTLKPDSYRVTLRPYLTPNDRGLYVFKGSSTVRFTCKEATDVIIIHSKKL--- 110 Query: 119 NATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVP-EKLTPHLK--------YYVAMDFQ 169 N TL + R + G + P ++ L+ P E L HLK Y + +F+ Sbjct: 111 NYTLS--QGHRVVLRG--VGGSQPPDIDKTELVEPTEYLVVHLKGSLVKDSQYEMDSEFE 166 Query: 170 AKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESR 229 +L D GFY+S Y G +++A T + AR +FPCFDEP KA F+I + Sbjct: 167 GELADDLAGFYRSEYME-GNVRKVVATTQMQAADARKSFPCFDEPAMKAEFNITLIHPKD 225 Query: 230 HIALSNM-PKVKTIEL--EGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSI 286 ALSNM PK + L + F TT KMSTYL+A+IV +F + S+GV + I Sbjct: 226 LTALSNMLPKGPSTPLPEDPNWNVTEFHTTPKMSTYLLAFIVSEFDYVEKQASNGVLIRI 285 Query: 287 YASPDKRNQTH--YALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITY 344 +A P H YAL + +L+F+ ++D YPL K D I +PDF GAMENWGL+TY Sbjct: 286 WARPSAIAAGHGDYALNVTGPILNFFAGHYDTPYPLPKSDQIGLPDFNAGAMENWGLVTY 345 Query: 345 RETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAV 404 RE SLLFDP +SS+S+K V VIAHELAHQWFGNLVT+EWWND+WL EGFA Y+E + Sbjct: 346 RENSLLFDPLSSSSSNKERVVTVIAHELAHQWFGNLVTIEWWNDLWLNEGFASYVEYLGA 405 Query: 405 NATYPELQFDDYF-LNVCFEVITKDSLNSSRPISKPA---ETPTQIQEMFDEVSYNKGAC 460 + P D LN + V+ D+L SS P+S PA TP QI E+FD +SY+KGA Sbjct: 406 DYAEPTWNLKDLMVLNDVYRVMAVDALASSHPLSTPASEINTPAQISELFDAISYSKGAS 465 Query: 461 ILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKM 520 +L ML FL E+ F++G+ YL F+Y+N +LW L + V + ++ Sbjct: 466 VLRMLSSFLSEDVFKQGLASYLHTFAYQNTIYLNLWDHLQEA----------VNNRSIQL 515 Query: 521 TSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPE---W 577 + V+++M WTLQ G P++ V D + L QE FL DP+ Sbjct: 516 PTT----------VRDIMNRWTLQMGFPVITV--DTSTGTLSQEHFLL-----DPDSNVT 558 Query: 578 RALQERYLWHIPLTYSTSSSNVIHRHILKSKT-DTLDLPEKTSWVKFNVDSNGYYIVHYE 636 R + Y+W +P+T ++ + + L WV N++ GYY V+Y+ Sbjct: 559 RPSEFNYVWIVPITSIRDGRQQQDYWLIDVRAQNDLFSTSGNEWVLLNLNVTGYYRVNYD 618 Query: 637 GHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPAL 696 W ++ TQL ++H+ + +R +I+D F L A ++ + AL+ T +L E Sbjct: 619 EENWRKIQTQLQRDHSAIPVINRAQIINDAFNLASAHKVPVTLALNNTLFLIEERQYMPW 678 Query: 697 LEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVI-----DRQSWSD-KGSVWDRML 750 LS L F M DR S++ +K YL + P+ + +W + ++ D+ Sbjct: 679 EAALSSLSYFKLMFDR---SEVYGPMKNYLKKQVTPLFIHFRNNTNNWREIPENLMDQYS 735 Query: 751 RSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVY--SVGAQTTAGWNYL 808 + AC C + + LF QWME+ I ++ VY ++ W++ Sbjct: 736 EVNAISTACSNGVPECEEMVSGLFKQWMENPNNNPIHPNLRSTVYCNAIAQGGEEEWDFA 795 Query: 809 LEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKG 868 EQ+ + E +K+ AL+ SK L + + + +I+ Q+ + + +I G Sbjct: 796 WEQFRNATLVNEADKLRAALACSKELWILNRYLSYTLNPDLIRKQDATSTIISITNNVIG 855 Query: 869 QQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQ--GS 926 Q L WDFV+ NW L + GS+ +I T FS++ +LQ+++ F + E GS Sbjct: 856 QGLVWDFVQSNWKKLFNDYGGGSFSFSNLIQAVTRRFSTEYELQQLEQFKKDNEETGFGS 915 Query: 927 HLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 960 + LE NIKW+++N + W N+ Sbjct: 916 GTRALEQALEKTKANIKWVKENKEVVLQWFTENS 949 >3RJO-A nrPDB Length = 419 Score = 386 bits (992), Expect = e-107, Method: Compositional matrix adjust. Identities = 183/411 (44%), Positives = 276/411 (67%), Gaps = 6/411 (1%) Query: 546 GIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHIL 605 G PL+ + G ++ ++QE +++G D A YLWH+PLT+ TS S+++HR +L Sbjct: 1 GFPLITITVRGRNVHMKQEHYMKG---SDG---APDTGYLWHVPLTFITSKSDMVHRFLL 54 Query: 606 KSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHD 665 K+KTD L LPE+ W+KFNV NGYYIVHYE GWD L L HT + DR LI++ Sbjct: 55 KTKTDVLILPEEVEWIKFNVGMNGYYIVHYEDDGWDSLTGLLKGTHTAVSSNDRASLINN 114 Query: 666 VFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRY 725 FQLV G+L+++KALD++ YL+HET + +GL+ L Y +M++R+++++ K + Sbjct: 115 AFQLVSIGKLSIEKALDLSLYLKHETEIMPVFQGLNELIPMYKLMEKRDMNEVETQFKAF 174 Query: 726 LLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLN 785 L++ + +ID+Q+W+D+GSV +RMLRS LL LAC N+ PC+Q+A F +W ES+G L+ Sbjct: 175 LIRLLRDLIDKQTWTDEGSVSERMLRSQLLLLACVHNYQPCVQRAEGYFRKWKESNGNLS 234 Query: 786 IPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGM 845 +P DV V++VGAQ+T GW++L +Y+ S+SS E+++I +AL ++++EKL L++ Sbjct: 235 LPVDVTLAVFAVGAQSTEGWDFLYSKYQFSLSSTEKSQIEFALCRTQNKEKLQWLLDESF 294 Query: 846 EGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHF 905 +G IKTQ +L I R P G LAW F+R+NW L++KF+LGS I ++ GTT F Sbjct: 295 KGDKIKTQEFPQILTLIGRNPVGYPLAWQFLRKNWNKLVQKFELGSSSIAHMVMGTTNQF 354 Query: 906 SSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWL 956 S++ +L+EVK FF SL+ GS L Q +ETI +NI W++KN +R WL Sbjct: 355 STRTRLEEVKGFFSSLKENGSQLRCVQQTIETIEENIGWMDKNFDKIRVWL 405 >4WZ9-A nrPDB Length = 957 Score = 375 bits (964), Expect = e-104, Method: Compositional matrix adjust. Identities = 261/838 (31%), Positives = 406/838 (48%), Gaps = 86/838 (10%) Query: 30 PQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNL--T 87 PQ+ S S + +++ G P ER+ RLP+ IP+HYDL + + Sbjct: 17 PQLPGASDLSGGVA---SDEIGVAPAQAVDERY-----RLPTTSIPIHYDLHLRTEIHRN 68 Query: 88 SLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPG--KELKVLSYPAH 145 F + I++ V AT +++H++ L +++A + S + P +++ + Sbjct: 69 ERTFTGTVGIQLQVVQATDKLVMHNRGLVMSSAKVSSLPNGVTGAPTLIGDVQYSTDTTF 128 Query: 146 EQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQAR 205 E I P L P Y + + FQ +L +GFY S+Y GE R LA T FE T AR Sbjct: 129 EHITFTSPTILQPG-TYLLEVAFQGRLATNDDGFYVSSYVADNGERRYLATTQFESTSAR 187 Query: 206 MAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVA 265 MAFPC+DEP KA F++ I + A+SNMP+ T ++E + FE T MSTYL+A Sbjct: 188 MAFPCYDEPGLKATFTVSITHSLSYKAISNMPQKTTTDIETDMRTTFFEKTPAMSTYLLA 247 Query: 266 YIVCDFH-SLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYP--LSK 322 ++V DF LSG +Y P+ N+ +AL+A +K+L + + I Y + K Sbjct: 248 FVVSDFQLRLSG------AQRVYVRPNAFNEATFALEAGVKILKVLDDHLGIPYDTYMPK 301 Query: 323 LDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVT 382 LD IAIPDFA GAMENWGL+TYRE +LLF+P S+ K V IAHE AHQWFGNLV+ Sbjct: 302 LDQIAIPDFAAGAMENWGLVTYREQALLFNPAVSTYRGKTNVATTIAHEYAHQWFGNLVS 361 Query: 383 MEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFE-VITKDSLNSSRPISKPAE 441 EWW IWL EGFA E A++ YP ++ + F + + +D S+RP++ A Sbjct: 362 PEWWEYIWLNEGFATLYEFYALDMAYPGQEYWELFNQQVIQYAMGQDGQASTRPMNWNAA 421 Query: 442 TPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSN 501 TP +I +FD V+Y+K +LNM++ LG++ ++ G+ YL + + A ++ L++ L + Sbjct: 422 TPGEISALFDRVAYDKSGSVLNMMRHVLGDDNWKAGLKAYLTDRALQGAVDEQLYAGLQS 481 Query: 502 SCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQ--DGCSL 559 + GV V ++M TWT + G P+L V++ D + Sbjct: 482 AIEGKGVLPNGVT-------------------VAQIMRTWTNEAGYPVLNVRRSYDTGDV 522 Query: 560 RLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHR----HILKSKTDTLDLP 615 + QERF R + +W IP Y + + L +K ++ Sbjct: 523 IISQERFYND--------RKVPNTNIWMIPYNYVHQAKADFNEFDDFQWLATKAARIETT 574 Query: 616 -EKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGR 674 W+ FN GYY V+Y+ H W+ + L++N + +R LI D + L +GR Sbjct: 575 VPANEWIVFNKQQVGYYRVNYDEHNWELITNALHENWASIHRLNRAQLIDDAYWLARSGR 634 Query: 675 LTLDKALDMTYYLQHE-------TSSPAL------LEGLSYLESFYHMMDRRNISDISEN 721 L L AL YL++E ++ AL L G + +F +D I DI Sbjct: 635 LDLRVALRFMTYLRNEREYAPWTAANVALTYFNNRLRGTAEYHNFLIFVDAL-IEDI--- 690 Query: 722 LKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESS 781 Y ID S D ++ + L + AC + + C+ K A L + Sbjct: 691 -------YSLLTIDAVSPDD--TLLHKYLVQTISTWACSMGYTDCLMKTAALLKAEASGT 741 Query: 782 GKLNIPTDVLKIVYSVGAQTT--AGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKL 837 G P D+ + Y G ++ + + YL + S + AE+ ++ +L S ++E L Sbjct: 742 GPAVHP-DIASVTYCYGMRSALESEFQYLYRKMMNSKNLAERTMLIDSLGCSNNKEFL 798 >1Z1W-A nrPDB Length = 780 Score = 275 bits (704), Expect = 5e-74, Method: Compositional matrix adjust. Identities = 181/590 (30%), Positives = 286/590 (48%), Gaps = 76/590 (12%) Query: 88 SLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQ 147 +LDF I+ N T+ I + D+ + LQ +MK +Y Sbjct: 9 TLDF----DIQKRTFNGTETITADAGDIVLDAVGLQIN----WMKVNGRDTAFTYDGQ-- 58 Query: 148 IALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMA 207 + P P + + F K+ D G Y G + T FE T AR Sbjct: 59 -TVRAPGDSQPQ---KIEISFAGKVSDSLSGIY------YAGRENGMITTHFEATDARRM 108 Query: 208 FPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYI 267 FPC D P +KA F+I + + + A+SNMP + E ++E F+ T +MSTYL+ Sbjct: 109 FPCVDHPAYKAVFAITVVIDKDYDAISNMPPKRIEVSERKVVE--FQDTPRMSTYLLYVG 166 Query: 268 VCDF-HSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLI 326 + F + + + + + K ++ Y L + K ++FYE YF I Y L K+ LI Sbjct: 167 IGKFRYEYEKYRD----IDLILASLKDIRSKYPLDMARKSVEFYENYFGIPYALPKMHLI 222 Query: 327 AIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWW 386 ++P+F GAMENWG IT+RE + + S+ + K VIAHE+AHQWFG+LVTM+WW Sbjct: 223 SVPEFGAGAMENWGAITFREIYMDI-AENSAVTVKRNSANVIAHEIAHQWFGDLVTMKWW 281 Query: 387 NDIWLKEGFAKYMELIAVNATYPELQF-DDYFLNVCFEVITKDSLNSSRPISKPAETPTQ 445 ND+WL E FA +M ++ +PE F D+F++ + DSL ++ PI P + Sbjct: 282 NDLWLNESFATFMSYKTMDTLFPEWSFWGDFFVSRTSGALRSDSLKNTHPIEVDVRDPDE 341 Query: 446 IQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLE 505 I ++FDE+SY KGA IL M++D+ G E+F+KGI +YL + NA+ DLW+++ + Sbjct: 342 ISQIFDEISYGKGASILRMIEDYAGYEEFRKGISKYLNDHKFGNAEGSDLWTAIED---- 397 Query: 506 SDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQER 565 SG VK +M W G P++ +K++G + + Q R Sbjct: 398 ---VSG--------------------KPVKRVMEYWIKNPGYPVIKLKRNGRKITMYQTR 434 Query: 566 FLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNV 625 FL +E+ W P+ + + + R +L+ + E +K N Sbjct: 435 FLLNG-EEEGRW-----------PVPVNIKKKDGVERILLEDEASI----EADGLIKINA 478 Query: 626 DSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRL 675 DS G+Y V Y+ D + + ++ L P DR+GL+ D+F + +G + Sbjct: 479 DSAGFYRVLYD----DATFSDVMGHYRDLSPLDRIGLVDDLFAFLLSGHI 524 >5DLL-A nrPDB Length = 867 Score = 119 bits (299), Expect = 5e-27, Method: Compositional matrix adjust. Identities = 119/408 (29%), Positives = 185/408 (45%), Gaps = 44/408 (10%) Query: 120 ATLQSEEDSRYMKPGKELKVLSY--------PA------HEQIALLVPEKLTPHLKYYVA 165 A ++ E++ + G ELK+LS PA ++ I VPEK L+ V Sbjct: 52 ANRENRENNTLVLDGVELKLLSIKLNNKHLSPAEFAVNENQLIINNVPEKFV--LQTVVE 109 Query: 166 MDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIR 225 ++ A EG YKS G+ + T E T R D P A F++KI Sbjct: 110 INPSANTS--LEGLYKS------GD---VFSTQCEATGFRKITYYLDRPDVMAAFTVKII 158 Query: 226 RESRH--IALSNMPKVKTIELEGGLLEDHF---ETTVKMSTYLVAYIVCDFHSLSG--FT 278 + + I LSN K+ + ++ HF + K YL A + D S+ T Sbjct: 159 ADKKKYPIILSNGDKIDSGDISDN---QHFAVWKDPFKKPCYLFALVAGDLASIKDTYIT 215 Query: 279 SSGVKVS--IYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAM 336 S KVS IYA ++ HYA+QA + + E F + Y L ++A+PDF GAM Sbjct: 216 KSQRKVSLEIYAFKQDIDKCHYAMQAVKDSMKWDEDRFGLEYDLDTFMIVAVPDFNAGAM 275 Query: 337 ENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFA 396 EN GL + ++ KT++ D V V+ HE H W G+ VT W + LKEG Sbjct: 276 ENKGLNIFNTKYIMASNKTATDKDFELVQSVVGHEYFHNWTGDRVTCRDWFQLSLKEGLT 335 Query: 397 KY--MELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVS 454 + E + + + DD + + +D+ S PI +P E+ ++ + Sbjct: 336 VFRDQEFTSDLNSRDVKRIDDVRI-IRSAQFAEDASPMSHPI-RP-ESYIEMNNFYTVTV 392 Query: 455 YNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNS 502 YNKGA I+ M+ LGEE FQKG+ Y ++ + DD ++++++ Sbjct: 393 YNKGAEIIRMIHTLLGEEGFQKGMKLYFERHDGQAVTCDDFVNAMADA 440 >5Y1X-A nrPDB Length = 914 Score = 115 bits (288), Expect = 1e-25, Method: Compositional matrix adjust. Identities = 93/320 (29%), Positives = 140/320 (43%), Gaps = 29/320 (9%) Query: 178 GFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIR--RESRHIALSN 235 G YKS + + V+ E T R D P A + + + +E + LSN Sbjct: 135 GLYKS---------KNIIVSQCEATGFRRITFFIDRPDMMAKYDVTVTADKEKYPVLLSN 185 Query: 236 MPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSG-----FTSSGVKVSIYASP 290 KV E+ GG F YL A + D LS +T V++ +++ Sbjct: 186 GDKVNEFEIPGGRHGARFNDPHLKPCYLFAVVAGDLKHLSATYITKYTKKKVELYVFSEE 245 Query: 291 DKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLL 350 ++ +AL+ K + F E YF + Y LS+L+L+A+ DF GAMEN GL + SLL Sbjct: 246 KYVSKLQWALECLKKSMAFDEDYFGLEYDLSRLNLVAVSDFNVGAMENKGLNIFNANSLL 305 Query: 351 FDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELI----AVNA 406 K S + V+ HE H + GN VT+ W + LKEG + E + Sbjct: 306 ASKKNSIDFSYARILTVVGHEYFHNYTGNRVTLRDWFQLTLKEGLTVHRENLFSEEMTKT 365 Query: 407 TYPELQFDDYFLNVCFEVITKDSLNSSRPISKP--AETPTQIQEMFDEVSYNKGACILNM 464 L D +V F L S P+S P E+ ++ + Y+KG+ ++ M Sbjct: 366 VTTRLSHVDLLRSVQF-------LEDSSPLSHPIRPESYVSMENFYTTTVYDKGSEVMRM 418 Query: 465 LKDFLGEEKFQKGIIQYLKK 484 LGEE ++KG Y+KK Sbjct: 419 YLTILGEEYYKKGFDIYIKK 438 >4QHP-A nrPDB Length = 870 Score = 100 bits (248), Expect = 4e-21, Method: Compositional matrix adjust. Identities = 81/317 (25%), Positives = 143/317 (45%), Gaps = 17/317 (5%) Query: 197 TDFEPTQARMAFPCFDEPLFKANFSIKIRRESRH--IALSNMPKVKTIELEGGLLEDHFE 254 T EP R D P + F+ I + + + LSN K+ E G +E Sbjct: 117 TQCEPEGFRKITFYIDRPDVMSKFTTTIVADKKRYPVLLSNGNKIDGGEFSDGRHWVKWE 176 Query: 255 TTVKMSTYLVAYIVCD-------FHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLL 307 +YL A + D F ++SG VK+ Y + + + +A+++ + Sbjct: 177 DPFSKPSYLFALVAGDLAVTEDYFTTMSG---RNVKIEFYTTEADKPKVGFAVESLKNAM 233 Query: 308 DFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRV 367 + E F + Y L ++A+ DF GAMEN GL + +L D +T++ +D + V Sbjct: 234 KWDETRFGLEYDLDIFMVVAVGDFNMGAMENKGLNIFNTKFVLADSRTATDTDFEGIESV 293 Query: 368 IAHELAHQWFGNLVTMEWWNDIWLKEGFAKY--MELIAVNATYPELQFDDYFLNVCFEVI 425 + HE H W GN VT W + LKEG + E A+ + ++ L + Sbjct: 294 VGHEYFHNWTGNRVTCRDWFQLSLKEGLTVFRDQEFSGDRASRAVRRIENIRL-LRQHQF 352 Query: 426 TKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKF 485 +D+ ++ P+ +PA + ++ + Y KGA ++ M LGEE FQKG+ Y ++ Sbjct: 353 PEDAGPTAHPV-RPA-SYEEMNNFYTMTVYEKGAEVVRMYHTLLGEEGFQKGMKLYFQRH 410 Query: 486 SYRNAKNDDLWSSLSNS 502 + DD ++++++ Sbjct: 411 DGQAVTCDDFRAAMADA 427 >4Q4I-A nrPDB Length = 891 Score = 97.8 bits (242), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 122/497 (24%), Positives = 188/497 (37%), Gaps = 71/497 (14%) Query: 117 ITNATLQSEEDSRYMKPGKELKVLSYPAH--------EQIALLVPEKLTPHLKYYVAMDF 168 ++ A D+ G++LK++S + E+ LV L + + Sbjct: 60 VSQAVRHGASDAPLRLNGEDLKLVSVHINDEPWTAWKEEEGALVISNLPERFTLKIINEI 119 Query: 169 QAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRES 228 EG Y+S G+ T E R D P A F+ KI + Sbjct: 120 SPAANTALEGLYQS------GDA---LCTQCEAEGFRHITYYLDRPDVLARFTTKIIADK 170 Query: 229 RH--IALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGF--TSSGVKV 284 LSN +V ELE G ++ YL A + DF L T SG +V Sbjct: 171 IKYPFLLSNGNRVAQGELENGRHWVQWQDPFPKPCYLFALVAGDFDVLRDTFTTRSGREV 230 Query: 285 SIYASPDKRN--QTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLI 342 ++ D+ N + +A+ + + + E+ F + Y L ++A+ F GAMEN GL Sbjct: 231 ALELYVDRGNLDRAPWAMTSLKNSMKWDEERFGLEYDLDIYMIVAVDFFNMGAMENKGLN 290 Query: 343 TYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELI 402 + +L T++ D L + RVI HE H W GN VT W + LKEG + + Sbjct: 291 IFNSKYVLARTDTATDKDYLDIERVIGHEYFHNWTGNRVTCRDWFQLSLKEGLTVFRD-- 348 Query: 403 AVNATYPELQFD--DYFLNVCFEVITKDSLN---SSRPISKPAETPTQIQEM---FDEVS 454 E D +N V T L + P++ P P + EM + Sbjct: 349 ------QEFSSDLGSRAVNRINNVRTMRGLQFAEDASPMAHPIR-PDMVIEMNNFYTLTV 401 Query: 455 YNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVC 514 Y KGA ++ M+ LGEE FQKG+ Y ++ A DD ++ D ++ + Sbjct: 402 YEKGAEVIRMIHTLLGEENFQKGMQLYFERHDGSAATCDDFVQAM------EDASNVDLS 455 Query: 515 HSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQED 574 H W Q G P++ VK D + E++ + Q Sbjct: 456 H----------------------FRRWYSQSGTPIVTVKDD---YNPETEQYTLTISQRT 490 Query: 575 PEWRALQERYLWHIPLT 591 P E+ HIP Sbjct: 491 PATPDQAEKQPLHIPFA 507 >3CIA-A nrPDB Length = 605 Score = 87.8 bits (216), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 89/340 (26%), Positives = 137/340 (40%), Gaps = 51/340 (15%) Query: 179 FYKSTYRTLG----------GETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRES 228 +Y ST + G G+ + + + AR P D P + ++ +I + Sbjct: 115 YYNSTEKATGLQWLSAEQTAGKEKPFLFSQNQAIHARSWIPIQDTPSVRVTYTARITTDK 174 Query: 229 RHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYA 288 +A+ + E +G F + YL+A V D F + + IYA Sbjct: 175 DLLAVMSANNEPGTERDGDYF---FSMPQAIPPYLIAIGVGDLE----FKAMSHQTGIYA 227 Query: 289 SPDKRNQTHYALQASLKLLDFYEKYFD----IY--YPLSKLDLIAIPDFAP-GAMENWGL 341 Y L A++ D + D +Y Y + DL+ +P P G MEN Sbjct: 228 E-------SYILDAAVAEFDDTQAMIDKAEQMYGKYRWGRYDLLMLPPSFPFGGMEN--- 277 Query: 342 ITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMEL 401 L F T A DK V +IAHELAH W GNLVT E W D+WL EGF Y+E Sbjct: 278 -----PRLSFITPTVVAGDKSLVN-LIAHELAHSWSGNLVTNESWRDLWLNEGFTSYVEN 331 Query: 402 IAVNATYP------ELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSY 455 + A + E LN E++ D+ ++ I P + F V Y Sbjct: 332 RIMEAVFGTDRAVMEQALGAQDLNA--EILELDASDTQLYIDLKGRDP---DDAFSGVPY 386 Query: 456 NKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDL 495 KG L L++ G E+F +++Y ++++ D+ Sbjct: 387 VKGQLFLMYLEEKFGRERFDAFVLEYFDSHAFQSLGTDNF 426 >2XPY-A nrPDB Length = 632 Score = 84.3 bits (207), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 91/327 (27%), Positives = 131/327 (40%), Gaps = 57/327 (17%) Query: 185 RTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIEL 244 +T GG+ + + E AR FPCFD P K+ F+ I S +P V Sbjct: 134 QTKGGKPYVFS--QLEAIHARSLFPCFDTPSVKSTFTASIE--------SPLPVV----F 179 Query: 245 EGGLLED--------HFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQT 296 G +ED FE V + YL+ D S G + ++Y P + Sbjct: 180 SGIRIEDTSKDTNIYRFEQKVPIPAYLIGIASGDLSS----APIGPRSTVYTEPFRLKDC 235 Query: 297 HYALQASL-KLLDFYEKYFDIYYPLSKLDLIAIPDFAP-GAMENWGLITYRETSLLFDPK 354 + + + K + EK Y D++ D P G ME+ ++ F Sbjct: 236 QWEFENDVEKFIQTAEKII-FEYEWGTYDILVNVDSYPYGGMES--------PNMTFATP 286 Query: 355 TSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATY--PELQ 412 T A D+ + VIAHELAH W GNLVT WN WL EG+ Y+E + A + P Sbjct: 287 TLIAHDRSNID-VIAHELAHSWSGNLVTNCSWNHFWLNEGWTVYLERRIIGAIHGEPTRH 345 Query: 413 FDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEM---------FDEVSYNKGACILN 463 F + D NS + P T +Q + F V Y KG +L Sbjct: 346 FSAL-------IGWSDLQNSIDSMKDPERFSTLVQNLNDNTDPDDAFSTVPYEKGFNLLF 398 Query: 464 MLKDFL-GEEKFQKGIIQYLKKFSYRN 489 L+ L G+ +F I Y KKF+ ++ Sbjct: 399 HLETILGGKAEFDPFIRHYFKKFAKKS 425 >4GAA-A nrPDB Length = 609 Score = 81.3 bits (199), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 99/430 (23%), Positives = 177/430 (41%), Gaps = 38/430 (8%) Query: 77 HYDLFVHPNLTSLDFVASEKIEVL-VSNATQFIILHSKDLEITNATLQSEEDSRYMKPGK 135 H L +H + TS AS + V + ++ +IL +KDL I + ++ + + Sbjct: 17 HMHLKLHVDFTSRAIAASTSLTVRSLQDSLASLILDTKDLTIKKVAVNGKDATFALGTTH 76 Query: 136 ELKVLSYPAHEQIALLVPEKLTPHLKYYVAMD-FQAKLGDGFEGFYKSTYRTLGGETRIL 194 K + + +P LT + V +D + + K G+ Sbjct: 77 SFK------GTPLEITLPFSLTRGQEVIVEIDSVTSPKSSALQWLNK---EQTAGKIHPY 127 Query: 195 AVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDH-- 252 + + T R PC D P K + ++ +AL M ++ EL + Sbjct: 128 LFSQCQATHCRSIIPCQDTPSVKFTYYSQVSVPKELMAL--MSALRDGELSEQSDSNRKI 185 Query: 253 --FETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFY 310 F+ V + +YL+A +V +L G G + +I+ + + Y + K+L + Sbjct: 186 YRFKQNVPIPSYLIALVVG---ALEG-RKVGPRTTIWTEKELLEPSVYEFAETEKMLKYA 241 Query: 311 EKYFDIYYPLSKLDLIAIP-DFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIA 369 E Y + DL+ +P F G MEN L T L D +S VIA Sbjct: 242 EDLAGPYV-WGQYDLLILPPSFPYGGMENPCLTFVTPTVLAGDRSLAS---------VIA 291 Query: 370 HELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVI--TK 427 HE++H W GNLVT E W + WL EG Y+E Y E +F + ++ + + Sbjct: 292 HEISHSWTGNLVTNETWENFWLNEGHTVYLERRIDGRLYGE-EFRQFKALGGWKELQNSV 350 Query: 428 DSLNSSRPISK--PAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQ-YLKK 484 ++ ++ P++ P + F V Y KG +L L+ LG + G ++ Y++ Sbjct: 351 NTFGATNPLTNLVPNLHEVDVDAAFSSVPYEKGFALLFYLEQLLGGPEIFLGFLKSYIQM 410 Query: 485 FSYRNAKNDD 494 F++++ ++ Sbjct: 411 FAFKSVTTEE 420 >5ZI5-A nrPDB Length = 921 Score = 79.7 bits (195), Expect = 5e-15, Method: Compositional matrix adjust. Identities = 78/320 (24%), Positives = 136/320 (42%), Gaps = 18/320 (5%) Query: 190 ETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKI--RRESRHIALSNMPKVKTIELEGG 247 ET +A+ E R F D P A + I +E + LSN ++ EL G Sbjct: 145 ETEGVALVKAESEGLRRVFYLPDRPDNLATYKTTIIANQEDYPVLLSNGVLIEKKELPLG 204 Query: 248 LLEDHFETTVKMSTYLVAYIVCDFHSLSGF--TSSGVKVSI--YASPDKRNQTHYALQAS 303 L + V +YL A + + + T SG ++ I Y P ++ +A + Sbjct: 205 LHSVTWLDDVPKPSYLFALVAGNLQRSVTYYQTKSGRELPIEFYVPPSATSKCDFAKEVL 264 Query: 304 LKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLW 363 + + + E+ F++ L + + + +A GA E GL + +L P+T + L Sbjct: 265 KEAMAWDERTFNLECALRQHMVAGVDKYASGASEPTGLNLFNTENLFASPETKTDLGILR 324 Query: 364 VTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFE 423 V V+AHE H W G+ VT+ W ++ LKEG + A + E + F Sbjct: 325 VLEVVAHEFFHYWSGDRVTIRDWFNLPLKEGLTTFRA-----AMFRE----ELFGTDLIR 375 Query: 424 VITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLK 483 ++ +L+ P T ++ ++ +Y K A I M+ F+G+E F + + ++ K Sbjct: 376 LLDGKNLDERAPRQSAY---TAVRSLYTAAAYEKSADIFRMMMLFIGKEPFIEAVAKFFK 432 Query: 484 KFSYRNAKNDDLWSSLSNSC 503 +D S+SNS Sbjct: 433 DNDGGAVTLEDFIESISNSS 452 >5FWQ-A nrPDB Length = 633 Score = 78.6 bits (192), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 79/299 (26%), Positives = 130/299 (43%), Gaps = 21/299 (7%) Query: 203 QARMAFPCFDEPLFKANFSIKIRRESRHIAL-SNMPKVKTIELEGGLLEDH-FETTVKMS 260 R PC D P K ++ ++ +AL S + +T + E + + F V + Sbjct: 154 HCRAILPCQDTPSVKLTYTAEVSVPKELVALMSAIRDGETPDPEDPSRKIYKFIQKVPIP 213 Query: 261 TYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPL 320 YL+A +V S G + +++ ++ ++ Y + +L E Y Sbjct: 214 CYLIALVVGALES----RQIGPRTLVWSEKEQVEKSAYEFSETESMLKIAEDLGGPYV-W 268 Query: 321 SKLDLIAIP-DFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGN 379 + DL+ +P F G MEN +T+ +LL A DK ++ VIAHE++H W GN Sbjct: 269 GQYDLLVLPPSFPYGGMEN-PCLTFVTPTLL-------AGDKS-LSNVIAHEISHSWTGN 319 Query: 380 LVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITK-DSLNSSRPISK 438 LVT + W+ WL EG Y+E + E L E+ + + P +K Sbjct: 320 LVTNKTWDHFWLNEGHTVYLERHICGRLFGEKFRHFNALGGWGELQNSVKTFGETHPFTK 379 Query: 439 PAETPTQIQE--MFDEVSYNKGACILNMLKDFLGEEKFQKGIIQ-YLKKFSYRNAKNDD 494 T I + V Y KG +L L+ LG + G ++ Y++KFSY++ DD Sbjct: 380 LVVDLTDIDPDVAYSSVPYEKGFALLFYLEQLLGGPEIFLGFLKAYVEKFSYKSITTDD 438 >3BIC-A nrPDB Length = 762 Score = 35.4 bits (80), Expect = 0.11, Method: Compositional matrix adjust. Identities = 26/72 (36%), Positives = 31/72 (43%), Gaps = 17/72 (23%) Query: 560 RLQQERFLQGVFQEDPEWRALQERYL---------WHIPLTYSTSSSNVIHRHILKSKTD 610 RL Q+R L PEW AL ++ L WH P S L SK D Sbjct: 16 RLIQQRLLHQQQPLHPEWAALAKKQLKGKNPEDLIWHTPEGISIKP--------LYSKRD 67 Query: 611 TLDLPEKTSWVK 622 T+DLPE+ VK Sbjct: 68 TMDLPEELPGVK 79 >4ZXO-A nrPDB Length = 352 Score = 32.7 bits (73), Expect = 0.89, Method: Compositional matrix adjust. Identities = 24/73 (32%), Positives = 32/73 (43%), Gaps = 1/73 (1%) Query: 811 QYELSMSSAEQNKILYALS-TSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQ 869 Q+E S + NK+L L+ K +K + L E G+EG LL I + P Sbjct: 238 QFERSQYIKQLNKMLTILTEAGKKHDKPIALTETGLEGIPDSLWWTGTLLPVIEKYPLSY 297 Query: 870 QLAWDFVRENWTH 882 L W RE TH Sbjct: 298 VLVWRNAREKSTH 310 >2B3Y-A nrPDB Length = 888 Score = 30.0 bits (66), Expect = 4.8, Method: Compositional matrix adjust. Identities = 14/42 (33%), Positives = 21/42 (50%), Gaps = 4/42 (9%) Query: 133 PGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMD----FQA 170 PG+ L E+ +++PE L P +K V +D FQA Sbjct: 819 PGENADALGLTGQERYTIIIPENLKPQMKVQVKLDTGKTFQA 860 >2DG8-A nrPDB Length = 193 Score = 30.0 bits (66), Expect = 5.1, Method: Composition-based stats. Identities = 19/57 (33%), Positives = 31/57 (54%), Gaps = 4/57 (7%) Query: 849 VIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGS-YDIRMIISGTTAH 904 ++ TQ L L AR+P ++L +++R + HL K FD G+ + +I G T H Sbjct: 104 LVLTQELYTL---AARQPAYRELTHEWMRRSRVHLEKHFDPGTARQLDALIEGLTLH 157 >1PBY-A nrPDB Length = 489 Score = 29.6 bits (65), Expect = 6.8, Method: Compositional matrix adjust. Identities = 15/54 (27%), Positives = 29/54 (53%), Gaps = 4/54 (7%) Query: 638 HGWDQLITQLNQNHTL-LRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHE 690 GWD +T++ +NH + L P++R ++ + G L+L + + Y L+ E Sbjct: 34 EGWDMTVTRMMRNHGVALEPEERAAIVRHLSDTRG---LSLAETEERRYILERE 84 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 3SE6-A nrPDB 1379 0.0 3QNF-A nrPDB 1191 0.0 5C97-A nrPDB 1058 0.0 5LG6-A nrPDB 1000 0.0 5LHD-A nrPDB 984 0.0 4KXA-A nrPDB 968 0.0 4WZ9-A nrPDB 797 0.0 3RJO-A nrPDB 567 e-161 1Z1W-A nrPDB 557 e-159 4Q4I-A nrPDB 445 e-125 5DLL-A nrPDB 417 e-116 4QHP-A nrPDB 403 e-112 4GAA-A nrPDB 389 e-108 5FWQ-A nrPDB 369 e-102 5Y1X-A nrPDB 366 e-101 5ZI5-A nrPDB 325 4e-89 3CIA-A nrPDB 307 2e-83 2XPY-A nrPDB 290 2e-78 Sequences not found previously or not previously below threshold: 4FGM-A nrPDB 37 0.034 4WNR-A nrPDB 35 0.21 3ZUK-A nrPDB 34 0.22 2C4R-L nrPDB 34 0.45 3MDV-A nrPDB 33 0.74 4AKR-A nrPDB 33 0.79 4DDQ-A nrPDB 32 1.6 4XBH-A nrPDB 32 1.6 1XMD-A nrPDB 31 3.8 6DRU-A nrPDB 30 5.2 1W8I-A nrPDB 30 5.3 CONVERGED! >3SE6-A nrPDB Length = 967 Score = 1379 bits (3569), Expect = 0.0, Method: Composition-based stats. Identities = 958/960 (99%), Positives = 958/960 (99%) Query: 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGE 60 M HSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGE Sbjct: 1 MVHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGE 60 Query: 61 RFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNA 120 RFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNA Sbjct: 61 RFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNA 120 Query: 121 TLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFY 180 TLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFY Sbjct: 121 TLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFY 180 Query: 181 KSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVK 240 KSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVK Sbjct: 181 KSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVK 240 Query: 241 TIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYAL 300 TIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYAL Sbjct: 241 TIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYAL 300 Query: 301 QASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASD 360 QASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASD Sbjct: 301 QASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASD 360 Query: 361 KLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNV 420 KLWVTRVIAHELAHQWFGNLVTMEWWNDIWL EGFAKYMELIAVNATYPELQFDDYFLNV Sbjct: 361 KLWVTRVIAHELAHQWFGNLVTMEWWNDIWLNEGFAKYMELIAVNATYPELQFDDYFLNV 420 Query: 421 CFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQ 480 CFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQ Sbjct: 421 CFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQ 480 Query: 481 YLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTT 540 YLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTT Sbjct: 481 YLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTT 540 Query: 541 WTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVI 600 WTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVI Sbjct: 541 WTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVI 600 Query: 601 HRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRV 660 HRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRV Sbjct: 601 HRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRV 660 Query: 661 GLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISE 720 GLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISE Sbjct: 661 GLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISE 720 Query: 721 NLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMES 780 NLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMES Sbjct: 721 NLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMES 780 Query: 781 SGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKL 840 SGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKL Sbjct: 781 SGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKL 840 Query: 841 IELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISG 900 IELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISG Sbjct: 841 IELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISG 900 Query: 901 TTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 960 TTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT Sbjct: 901 TTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 960 >3QNF-A nrPDB Length = 954 Score = 1191 bits (3081), Expect = 0.0, Method: Composition-based stats. Identities = 472/921 (51%), Positives = 636/921 (69%), Gaps = 11/921 (1%) Query: 39 SVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIE 98 S PS TE A P ++G FPW ++RLP VIP+HYDL +H NLT+L F + K+E Sbjct: 33 STPSWCQSTE---ASPKRSDGTPFPWNKIRLPEYVIPVHYDLLIHANLTTLTFWGTTKVE 89 Query: 99 VLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTP 158 + S T IILHS L+I+ ATL+ R + + L+VL +P EQIALL PE L Sbjct: 90 ITASQPTSTIILHSHHLQISRATLRKGAGERLSE--EPLQVLEHPRQEQIALLAPEPLLV 147 Query: 159 HLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKA 218 L Y V + + L + F GFYKSTYRT GE RILA T FEPT ARMAFPCFDEP FKA Sbjct: 148 GLPYTVVIHYAGNLSETFHGFYKSTYRTKEGELRILASTQFEPTAARMAFPCFDEPAFKA 207 Query: 219 NFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFT 278 +FSIKIRRE RH+A+SNMP VK++ + GL+EDHF+ TVKMSTYLVA+I+ DF S+S T Sbjct: 208 SFSIKIRREPRHLAISNMPLVKSVTVAEGLIEDHFDVTVKMSTYLVAFIISDFESVSKIT 267 Query: 279 SSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMEN 338 SGVKVS+YA PDK NQ YAL A++ LL+FYE YF I YPL K DL AIPDF GAMEN Sbjct: 268 KSGVKVSVYAVPDKINQADYALDAAVTLLEFYEDYFSIPYPLPKQDLAAIPDFQSGAMEN 327 Query: 339 WGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKY 398 WGL TYRE++LLFD + SSAS KL +T +AHELAHQWFGNLVTMEWWND+WL EGFAK+ Sbjct: 328 WGLTTYRESALLFDAEKSSASSKLGITMTVAHELAHQWFGNLVTMEWWNDLWLNEGFAKF 387 Query: 399 MELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKG 458 ME ++V+ T+PEL+ DYF CF+ + D+LNSS P+S P E P QI+EMFD+VSY+KG Sbjct: 388 MEFVSVSVTHPELKVGDYFFGKCFDAMEVDALNSSHPVSTPVENPAQIREMFDDVSYDKG 447 Query: 459 ACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDP 518 ACILNML+++L + F+ GI+QYL+K SY+N KN+DLW S+++ C S Sbjct: 448 ACILNMLREYLSADAFKSGIVQYLQKHSYKNTKNEDLWDSMASICPTDGVKGMDGFCSRS 507 Query: 519 KMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWR 578 + +S+ + E +VK MM TWTLQKG PL+ + G ++ ++QE +++G Sbjct: 508 QHSSSSSHWHQEGVDVKTMMNTWTLQKGFPLITITVRGRNVHMKQEHYMKGSDG------ 561 Query: 579 ALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGH 638 A YLWH+PLT+ TS S+++HR +LK+KTD L LPE+ W+KFNV NGYYIVHYE Sbjct: 562 APDTGYLWHVPLTFITSKSDMVHRFLLKTKTDVLILPEEVEWIKFNVGMNGYYIVHYEDD 621 Query: 639 GWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLE 698 GWD L L HT + DR LI++ FQLV G+L+++KALD++ YL+HET + + Sbjct: 622 GWDSLTGLLKGTHTAVSSNDRASLINNAFQLVSIGKLSIEKALDLSLYLKHETEIMPVFQ 681 Query: 699 GLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLA 758 GL+ L Y +M++R+++++ K +L++ + +ID+Q+W+D+GSV +RMLRS LL LA Sbjct: 682 GLNELIPMYKLMEKRDMNEVETQFKAFLIRLLRDLIDKQTWTDEGSVSERMLRSQLLLLA 741 Query: 759 CDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSS 818 C N+ PC+Q+A F +W ES+G L++P DV V++VGAQ+T GW++L +Y+ S+SS Sbjct: 742 CVHNYQPCVQRAEGYFRKWKESNGNLSLPVDVTLAVFAVGAQSTEGWDFLYSKYQFSLSS 801 Query: 819 AEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRE 878 E+++I +AL ++++EKL L++ +G IKTQ +L I R P G LAW F+R+ Sbjct: 802 TEKSQIEFALCRTQNKEKLQWLLDESFKGDKIKTQEFPQILTLIGRNPVGYPLAWQFLRK 861 Query: 879 NWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETI 938 NW L++KF+LGS I ++ GTT FS++ +L+EVK FF SL+ GS L Q +ETI Sbjct: 862 NWNKLVQKFELGSSSIAHMVMGTTNQFSTRTRLEEVKGFFSSLKENGSQLRCVQQTIETI 921 Query: 939 TKNIKWLEKNLPTLRTWLMVN 959 +NI W++KN +R WL Sbjct: 922 EENIGWMDKNFDKIRVWLQSE 942 >5C97-A nrPDB Length = 912 Score = 1058 bits (2735), Expect = 0.0, Method: Composition-based stats. Identities = 399/908 (43%), Positives = 558/908 (61%), Gaps = 36/908 (3%) Query: 56 ATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDL 115 ATNG+ FPW ++RLP+ V+PL Y+L +HPNLTS+ F S I V T IILHS Sbjct: 32 ATNGKLFPWAQIRLPTAVVPLRYELSLHPNLTSMTFRGSVTISVQALQVTWNIILHSTGH 91 Query: 116 EITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDG 175 I+ T S S+ K+ ++L Y H QIA++ PE L Y + +++ A + Sbjct: 92 NISRVTFMSAVSSQ----EKQAEILEYAYHGQIAIVAPEALLAGHNYTLKIEYSANISSS 147 Query: 176 FEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSN 235 + GFY +Y E + A T FEP AR AFPCFDEP FKA F IKI R+ ++ ALSN Sbjct: 148 YYGFYGFSYTDESNEKKYFAATQFEPLAARSAFPCFDEPAFKATFIIKIIRDEQYTALSN 207 Query: 236 MPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQ 295 MPK ++ L+ GL++D F +VKMSTYLVA+IV + +LS +G VSIYA P+K Q Sbjct: 208 MPKKSSVVLDDGLVQDEFSESVKMSTYLVAFIVGEMKNLSQ-DVNGTLVSIYAVPEKIGQ 266 Query: 296 THYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKT 355 HYAL+ ++KLL+F++ YF+I YPL KLDL+AIPDF GAMENWGL+T+RE +LL+D T Sbjct: 267 VHYALETTVKLLEFFQNYFEIQYPLKKLDLVAIPDFEAGAMENWGLLTFREETLLYDSNT 326 Query: 356 SSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDD 415 SS +D+ VT++IAHELAHQWFGNLVTM+WWND+WL EGFA +ME ++ + EL + Sbjct: 327 SSMADRKLVTKIIAHELAHQWFGNLVTMKWWNDLWLNEGFATFMEYFSLEKIFKELSSYE 386 Query: 416 YFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQ 475 FL+ F+ + KDSLNSS PIS ++ QI+EMFD +SY KG+ +L MLK +L E+ FQ Sbjct: 387 DFLDARFKTMKKDSLNSSHPISSSVQSSEQIEEMFDSLSYFKGSSLLLMLKTYLSEDVFQ 446 Query: 476 KGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVK 535 ++ YL SY + ++DDLW S + ++ +VK Sbjct: 447 HAVVLYLHNHSYASIQSDDLWDSFNEVTNQT-------------------------LDVK 481 Query: 536 EMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTS 595 MM TWTLQKG PL+ V++ G L +QQERF + PE + YLWHIPL+Y T Sbjct: 482 RMMKTWTLQKGFPLVTVQKKGKELFIQQERFFLNM---KPEIQPSDTSYLWHIPLSYVTE 538 Query: 596 SSNVIHRH---ILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHT 652 N +L K+ ++L E+ WVK N++ NGYYIVHY W+ LI QL N Sbjct: 539 GRNYSKYQSVSLLDKKSGVINLTEEVLWVKVNINMNGYYIVHYADDDWEALIHQLKINPY 598 Query: 653 LLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDR 712 +L KDR LI+++F+L G G++ L +A D+ YL +E + + E L + Y+++++ Sbjct: 599 VLSDKDRANLINNIFELAGLGKVPLKRAFDLINYLGNENHTAPITEALFQTDLIYNLLEK 658 Query: 713 RNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAE 772 D++ L + + + I +Q+W+D+G+ R LRSALL+ AC N C A + Sbjct: 659 LGYMDLASRLVTRVFKLLQNQIQQQTWTDEGTPSMRELRSALLEFACTHNLGNCSTTAMK 718 Query: 773 LFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSK 832 LF WM S+G ++PTDV+ V+ VGA+T GW++LL +Y S AE+NKIL AL++S+ Sbjct: 719 LFDDWMASNGTQSLPTDVMTTVFKVGAKTDKGWSFLLGKYISIGSEAEKNKILEALASSE 778 Query: 833 HQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSY 892 KL L++ + G +TQ L+ ++ + R G LAWDFV+ENW L++KF LGSY Sbjct: 779 DVRKLYWLMKSSLNGDNFRTQKLSFIIRTVGRHFPGHLLAWDFVKENWNKLVQKFPLGSY 838 Query: 893 DIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTL 952 I+ I++G+T FS+K L EV+ FFE+ L Q LE I NI+W+EKNL +L Sbjct: 839 TIQNIVAGSTYLFSTKTHLSEVQAFFENQSEATFRLRCVQEALEVIQLNIQWMEKNLKSL 898 Query: 953 RTWLMVNT 960 WL T Sbjct: 899 TWWLRTET 906 >5LG6-A nrPDB Length = 968 Score = 1000 bits (2586), Expect = 0.0, Method: Composition-based stats. Identities = 309/972 (31%), Positives = 472/972 (48%), Gaps = 71/972 (7%) Query: 29 LPQICICSQFSVPSSYHFTEDPGAFPVATN---------GERFPWQELRLPSVVIPLHYD 79 +P P E P + + PW RLP+ ++P Y+ Sbjct: 5 VPDYAGAQPARSPEKNKNAEHVPQAPTSPTITTTAAITLDQSKPWNRYRLPTTLLPDSYN 64 Query: 80 LFVHPNLTSLD-----FVASEKIEVLVSNATQFIILHSKDLEITN----ATLQSEEDSRY 130 + + P LT F + + T II+HSK L T L+ DS+ Sbjct: 65 VTLRPYLTPNADGLYIFKGKSIVRFICQEPTDVIIIHSKKLNYTTQGHMVVLRGVGDSQV 124 Query: 131 MKPGK-ELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGG 189 + + EL L+ E + + + L P Y + +FQ +L D GFY+S Y G Sbjct: 125 PEIDRTELVELT----EYLVVHLKGSLQPGHMYEMESEFQGELADDLAGFYRSEYM-EGN 179 Query: 190 ETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIEL---EG 246 ++LA T + T AR +FPCFDEP KA F+I + + ALSNMP + + Sbjct: 180 VKKVLATTQMQSTDARKSFPCFDEPAMKATFNITLIHPNNLTALSNMPPKGSSTPLAEDP 239 Query: 247 GLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTH--YALQASL 304 FETT MSTYL+AYIV +F S++ +GV + I+A P+ + H YAL + Sbjct: 240 NWSVTEFETTPVMSTYLLAYIVSEFQSVNETAQNGVLIRIWARPNAIAEGHGMYALNVTG 299 Query: 305 KLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWV 364 +L+F+ +++ YPL K D IA+PDF GAMENWGL+TYRE +LLFDP++SS S+K V Sbjct: 300 PILNFFANHYNTSYPLPKSDQIALPDFNAGAMENWGLVTYRENALLFDPQSSSISNKERV 359 Query: 365 TRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFL-NVCFE 423 VIAHELAHQWFGNLVT+ WWND+WL EGFA Y+E + + P D + + Sbjct: 360 VTVIAHELAHQWFGNLVTLAWWNDLWLNEGFASYVEYLGADHAEPTWNLKDLIVPGDVYR 419 Query: 424 VITKDSLNSSRPISKPAE---TPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQ 480 V+ D+L SS P++ PAE TP QI EMFD +SY+KGA ++ ML +FL E+ F++G+ Sbjct: 420 VMAVDALASSHPLTTPAEEVNTPAQISEMFDSISYSKGASVIRMLSNFLTEDLFKEGLAS 479 Query: 481 YLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTT 540 YL F+Y+N DLW L + TS L V+ +M Sbjct: 480 YLHAFAYQNTTYLDLWEHLQKAV--------------DAQTSIRLP-----DTVRAIMDR 520 Query: 541 WTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVI 600 WTLQ G P++ V D + + Q+ FL E R+ YLW +P++ + Sbjct: 521 WTLQMGFPVITV--DTKTGNISQKHFLLD--SESNVTRSSAFDYLWIVPISSIKNGVMQD 576 Query: 601 HRHILKSK--TDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKD 658 H + + L WV NV+ GY+ V+Y+ W + QL N +++ + Sbjct: 577 HYWLRDVSQAQNDLFKTASDDWVLLNVNVTGYFQVNYDEDNWRMIQHQLQTNLSVIPVIN 636 Query: 659 RVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDI 718 R +I+D F L A + + ALD T +L E LS L F M DR S++ Sbjct: 637 RAQVIYDSFNLATAHMVPVTLALDNTLFLNGEKEYMPWQAALSSLSYFSLMFDR---SEV 693 Query: 719 SENLKRYLLQYFKPVIDR-----QSWSDKG-SVWDRMLRSALLKLACDLNHAPCIQKAAE 772 +K+YL + +P+ ++W+++ ++ D+ + AC C A Sbjct: 694 YGPMKKYLRKQVEPLFQHFETLTKNWTERPENLMDQYSEINAISTACSNGLPQCENLAKT 753 Query: 773 LFSQWMESSGKLNIPTDVLKIVYS--VGAQTTAGWNYLLEQYELSMSSAEQNKILYALST 830 LF QWM I ++ +Y + W++ Q + + E +K+ AL+ Sbjct: 754 LFDQWMSDPENNPIHPNLRSTIYCNAIAQGGQDQWDFAWGQLQQAQLVNEADKLRSALAC 813 Query: 831 SKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLG 890 S L + + + +I+ Q+ + +++IA GQ LAWDFV+ NW L + + G Sbjct: 814 SNEVWLLNRYLGYTLNPDLIRKQDATSTINSIASNVIGQPLAWDFVQSNWKKLFQDYGGG 873 Query: 891 SYDIRMIISGTTAHFSSKDKLQEVKLFFESLE--AQGSHLDIFQTVLETITKNIKWLEKN 948 S+ +I G T FSS+ +LQ+++ F ++ GS + LE NIKW+++N Sbjct: 874 SFSFSNLIQGVTRRFSSEFELQQLEQFKKNNMDVGFGSGTRALEQALEKTKANIKWVKEN 933 Query: 949 LPTLRTWLMVNT 960 + W + ++ Sbjct: 934 KEVVLNWFIEHS 945 >5LHD-A nrPDB Length = 950 Score = 984 bits (2544), Expect = 0.0, Method: Composition-based stats. Identities = 309/958 (32%), Positives = 464/958 (48%), Gaps = 66/958 (6%) Query: 33 CICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLD-- 90 + S + PS+ T T + W RLP+ + P Y + + P LT D Sbjct: 28 PVAS--TTPSASATTNP---ASATTLDQSKAWNRYRLPNTLKPDSYRVTLRPYLTPNDRG 82 Query: 91 ---FVASEKIEVLVSNATQFIILHSKDLEIT-----NATLQSEEDSRYMKPGKELKVLSY 142 F S + AT II+HSK L T L+ S+ P K Sbjct: 83 LYVFKGSSTVRFTCKEATDVIIIHSKKLNYTLSQGHRVVLRGVGGSQ---PPDIDKTELV 139 Query: 143 PAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPT 202 E + + + L +Y + +F+ +L D GFY+S Y G +++A T + Sbjct: 140 EPTEYLVVHLKGSLVKDSQYEMDSEFEGELADDLAGFYRSEYM-EGNVRKVVATTQMQAA 198 Query: 203 QARMAFPCFDEPLFKANFSIKIRRESRHIALSNM-PKVKTIELEGG--LLEDHFETTVKM 259 AR +FPCFDEP KA F+I + ALSNM PK + L F TT KM Sbjct: 199 DARKSFPCFDEPAMKAEFNITLIHPKDLTALSNMLPKGPSTPLPEDPNWNVTEFHTTPKM 258 Query: 260 STYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTH--YALQASLKLLDFYEKYFDIY 317 STYL+A+IV +F + S+GV + I+A P H YAL + +L+F+ ++D Sbjct: 259 STYLLAFIVSEFDYVEKQASNGVLIRIWARPSAIAAGHGDYALNVTGPILNFFAGHYDTP 318 Query: 318 YPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWF 377 YPL K D I +PDF GAMENWGL+TYRE SLLFDP +SS+S+K V VIAHELAHQWF Sbjct: 319 YPLPKSDQIGLPDFNAGAMENWGLVTYRENSLLFDPLSSSSSNKERVVTVIAHELAHQWF 378 Query: 378 GNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYF-LNVCFEVITKDSLNSSRPI 436 GNLVT+EWWND+WL EGFA Y+E + + P D LN + V+ D+L SS P+ Sbjct: 379 GNLVTIEWWNDLWLNEGFASYVEYLGADYAEPTWNLKDLMVLNDVYRVMAVDALASSHPL 438 Query: 437 SKPA---ETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKND 493 S PA TP QI E+FD +SY+KGA +L ML FL E+ F++G+ YL F+Y+N Sbjct: 439 STPASEINTPAQISELFDAISYSKGASVLRMLSSFLSEDVFKQGLASYLHTFAYQNTIYL 498 Query: 494 DLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVK 553 +LW L + V + ++ + V+++M WTLQ G P++ V Sbjct: 499 NLWDHLQEA----------VNNRSIQLPTT----------VRDIMNRWTLQMGFPVITV- 537 Query: 554 QDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKT-DTL 612 D + L QE FL R + Y+W +P+T ++ + + L Sbjct: 538 -DTSTGTLSQEHFLLDPD--SNVTRPSEFNYVWIVPITSIRDGRQQQDYWLIDVRAQNDL 594 Query: 613 DLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGA 672 WV N++ GYY V+Y+ W ++ TQL ++H+ + +R +I+D F L A Sbjct: 595 FSTSGNEWVLLNLNVTGYYRVNYDEENWRKIQTQLQRDHSAIPVINRAQIINDAFNLASA 654 Query: 673 GRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKP 732 ++ + AL+ T +L E LS L F M DR S++ +K YL + P Sbjct: 655 HKVPVTLALNNTLFLIEERQYMPWEAALSSLSYFKLMFDR---SEVYGPMKNYLKKQVTP 711 Query: 733 VI-----DRQSWSD-KGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNI 786 + + +W + ++ D+ + AC C + + LF QWME+ I Sbjct: 712 LFIHFRNNTNNWREIPENLMDQYSEVNAISTACSNGVPECEEMVSGLFKQWMENPNNNPI 771 Query: 787 PTDVLKIVYS--VGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELG 844 ++ VY + W++ EQ+ + E +K+ AL+ SK L + + Sbjct: 772 HPNLRSTVYCNAIAQGGEEEWDFAWEQFRNATLVNEADKLRAALACSKELWILNRYLSYT 831 Query: 845 MEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAH 904 + +I+ Q+ + + +I GQ L WDFV+ NW L + GS+ +I T Sbjct: 832 LNPDLIRKQDATSTIISITNNVIGQGLVWDFVQSNWKKLFNDYGGGSFSFSNLIQAVTRR 891 Query: 905 FSSKDKLQEVKLFFESLEA--QGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 960 FS++ +LQ+++ F + E GS + LE NIKW+++N + W N+ Sbjct: 892 FSTEYELQQLEQFKKDNEETGFGSGTRALEQALEKTKANIKWVKENKEVVLQWFTENS 949 >4KXA-A nrPDB Length = 888 Score = 968 bits (2501), Expect = 0.0, Method: Composition-based stats. Identities = 314/915 (34%), Positives = 489/915 (53%), Gaps = 56/915 (6%) Query: 56 ATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDL 115 A+ E W+ RLP V P+HYDL V P L + + I + +S T+++ LH ++ Sbjct: 5 ASEDESGQWKNFRLPDFVNPVHYDLHVKPLLEEDTYTGTVSISINLSAPTRYLWLHLRET 64 Query: 116 EITNATLQSEEDSRYMKPGKELKV---LSYPAHEQIALLVPEKLTPHLK---YYVAMDFQ 169 IT G +++V Y E + + E+LTP Y + M+F Sbjct: 65 RITRLPELKRPS------GDQVQVRRCFEYKKQEYVVVEAEEELTPSSGDGLYLLTMEFA 118 Query: 170 AKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESR 229 L GFY++TY T G + +A TD EPT AR +FPCFDEP KA ++I I Sbjct: 119 GWLNGSLVGFYRTTY-TENGRVKSIAATDHEPTDARKSFPCFDEPNKKATYTISITHPKE 177 Query: 230 HIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYAS 289 + ALSNMP K ++ FE +V MSTYLV + V F S+ ++SG ++IY Sbjct: 178 YGALSNMPVAKEESVDDKWTRTTFEKSVPMSTYLVCFAVHQFDSVKRISNSGKPLTIYVQ 237 Query: 290 PDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSL 349 P++++ YA + + D++E+YF + Y L KLD IAIPDF GAMENWGLITYRET+L Sbjct: 238 PEQKHTAEYAANITKSVFDYFEEYFAMNYSLPKLDKIAIPDFGTGAMENWGLITYRETNL 297 Query: 350 LFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYP 409 L+DPK S++S++ V V+AHEL HQWFGN+VTM+WW D+WL EGFA + E + VN Sbjct: 298 LYDPKESASSNQQRVATVVAHELVHQWFGNIVTMDWWEDLWLNEGFASFFEFLGVNHAET 357 Query: 410 ELQFDD-YFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDF 468 + Q D L V DSL SS PI TP +I +FD +SY+KG+ IL ML+D+ Sbjct: 358 DWQMRDQMLLEDVLPVQEDDSLMSSHPIIVTVTTPDEITSVFDGISYSKGSSILRMLEDW 417 Query: 469 LGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFL 528 + E FQKG YL+K+ ++NAK D W++L + Sbjct: 418 IKPENFQKGCQMYLEKYQFKNAKTSDFWAALEEAS------------------------- 452 Query: 529 GENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHI 588 VKE+M TWT Q G P+L V +G + Q+RFL + +P Y W+I Sbjct: 453 --RLPVKEVMDTWTRQMGYPVLNV--NGVK-NITQKRFLLDP-RANPSQPPSDLGYTWNI 506 Query: 589 PLTY---STSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLIT 645 P+ + + +SS + +R + T P +++K N D G+Y V+YE WD + T Sbjct: 507 PVKWTEDNITSSVLFNRSEKEGITLNSSNPSGNAFLKINPDHIGFYRVNYEVATWDSIAT 566 Query: 646 QLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLES 705 L+ NH DR LI D F L A L AL++T YL+ E + +S + Sbjct: 567 ALSLNHKTFSSADRASLIDDAFALARAQLLDYKVALNLTKYLKREENFLPWQRVISAVTY 626 Query: 706 FYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAP 765 M + + ++ ++ Y KP+ D W+D G ++LRS++L AC + Sbjct: 627 IISMFE--DDKELYPMIEEYFQGQVKPIADSLGWNDAGDHVTKLLRSSVLGFACKMGDRE 684 Query: 766 CIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAG---WNYLLEQYELSMSSAEQN 822 + A+ LF QW+ +G +++P ++ +VY G Q + WNY LEQY+ + + E+ Sbjct: 685 ALNNASSLFEQWL--NGTVSLPVNLRLLVYRYGMQNSGNEISWNYTLEQYQKTSLAQEKE 742 Query: 823 KILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTH 882 K+LY L++ K+ L + ++L + +IKTQ++ ++ I+ G+ +AW++++ NW + Sbjct: 743 KLLYGLASVKNVTLLSRYLDLLKDTNLIKTQDVFTVIRYISYNSYGKNMAWNWIQLNWDY 802 Query: 883 LLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNI 942 L+ ++ L + ++ I++ F+++ +L +++ FF G+ + VLET+ NI Sbjct: 803 LVNRYTLNNRNLGRIVT-IAEPFNTELQLWQMESFFAKYPQAGAGEKPREQVLETVKNNI 861 Query: 943 KWLEKNLPTLRTWLM 957 +WL+++ T+R W Sbjct: 862 EWLKQHRNTIREWFF 876 >4WZ9-A nrPDB Length = 957 Score = 797 bits (2059), Expect = 0.0, Method: Composition-based stats. Identities = 270/958 (28%), Positives = 441/958 (46%), Gaps = 105/958 (10%) Query: 30 PQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNL--T 87 PQ+ S S + +++ G P ER+ RLP+ IP+HYDL + + Sbjct: 17 PQLPGASDLSGGVA---SDEIGVAPAQAVDERY-----RLPTTSIPIHYDLHLRTEIHRN 68 Query: 88 SLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPG--KELKVLSYPAH 145 F + I++ V AT +++H++ L +++A + S + P +++ + Sbjct: 69 ERTFTGTVGIQLQVVQATDKLVMHNRGLVMSSAKVSSLPNGVTGAPTLIGDVQYSTDTTF 128 Query: 146 EQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQAR 205 E I P L P Y + + FQ +L +GFY S+Y GE R LA T FE T AR Sbjct: 129 EHITFTSPTILQPG-TYLLEVAFQGRLATNDDGFYVSSYVADNGERRYLATTQFESTSAR 187 Query: 206 MAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVA 265 MAFPC+DEP KA F++ I + A+SNMP+ T ++E + FE T MSTYL+A Sbjct: 188 MAFPCYDEPGLKATFTVSITHSLSYKAISNMPQKTTTDIETDMRTTFFEKTPAMSTYLLA 247 Query: 266 YIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYP--LSKL 323 ++V DF SG + +Y P+ N+ +AL+A +K+L + + I Y + KL Sbjct: 248 FVVSDFQ----LRLSGAQ-RVYVRPNAFNEATFALEAGVKILKVLDDHLGIPYDTYMPKL 302 Query: 324 DLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTM 383 D IAIPDFA GAMENWGL+TYRE +LLF+P S+ K V IAHE AHQWFGNLV+ Sbjct: 303 DQIAIPDFAAGAMENWGLVTYREQALLFNPAVSTYRGKTNVATTIAHEYAHQWFGNLVSP 362 Query: 384 EWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFE-VITKDSLNSSRPISKPAET 442 EWW IWL EGFA E A++ YP ++ + F + + +D S+RP++ A T Sbjct: 363 EWWEYIWLNEGFATLYEFYALDMAYPGQEYWELFNQQVIQYAMGQDGQASTRPMNWNAAT 422 Query: 443 PTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNS 502 P +I +FD V+Y+K +LNM++ LG++ ++ G+ YL + + A ++ L++ L ++ Sbjct: 423 PGEISALFDRVAYDKSGSVLNMMRHVLGDDNWKAGLKAYLTDRALQGAVDEQLYAGLQSA 482 Query: 503 CLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQ--DGCSLR 560 GV V ++M TWT + G P+L V++ D + Sbjct: 483 IEGKGVLPNGVT-------------------VAQIMRTWTNEAGYPVLNVRRSYDTGDVI 523 Query: 561 LQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHR----HILKSKTDTLDLP- 615 + QERF R + +W IP Y + + L +K ++ Sbjct: 524 ISQERFYND--------RKVPNTNIWMIPYNYVHQAKADFNEFDDFQWLATKAARIETTV 575 Query: 616 EKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRL 675 W+ FN GYY V+Y+ H W+ + L++N + +R LI D + L +GRL Sbjct: 576 PANEWIVFNKQQVGYYRVNYDEHNWELITNALHENWASIHRLNRAQLIDDAYWLARSGRL 635 Query: 676 TLDKALDMTYYLQHETSSPAL-------------LEGLSYLESFYHMMDRRNISDISENL 722 L AL YL++E L G + +F +D I DI L Sbjct: 636 DLRVALRFMTYLRNEREYAPWTAANVALTYFNNRLRGTAEYHNFLIFVDAL-IEDIYSLL 694 Query: 723 KRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSG 782 ID S D ++ + L + AC + + C+ K A L +G Sbjct: 695 ----------TIDAVSPDD--TLLHKYLVQTISTWACSMGYTDCLMKTAALLKAEASGTG 742 Query: 783 KLNIPTDVLKIVYSVGAQT--TAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKL 840 P D+ + Y G ++ + + YL + S + AE+ ++ +L S ++E L Sbjct: 743 PAVHP-DIASVTYCYGMRSALESEFQYLYRKMMNSKNLAERTMLIDSLGCSNNKEFLKAF 801 Query: 841 IELGMEGK-----VIKTQNLAALLHAI-ARRPKGQQLAWDFVRENWTHLLKKF--DLGSY 892 + + + ++ AI + G +F+ + L+ +F L + Sbjct: 802 LTTALGSGTGVEINYRADERRRVVQAIYSGGRTGVDALIEFLMD--PALVNEFVSTLSTS 859 Query: 893 DIRMIISGTTAHFSSKDKLQEVKLFFES-----LEAQGSHLDIFQTVLETITKNIKWL 945 + +S + ++ +++ ++ + ++L T N+ W+ Sbjct: 860 TLNSALSAIASRTNNVEEMNKLNALITALGSRVNSQTAANLRT------TAQANLDWV 911 >3RJO-A nrPDB Length = 419 Score = 567 bits (1460), Expect = e-161, Method: Composition-based stats. Identities = 182/414 (43%), Positives = 275/414 (66%), Gaps = 6/414 (1%) Query: 546 GIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHIL 605 G PL+ + G ++ ++QE +++G A YLWH+PLT+ TS S+++HR +L Sbjct: 1 GFPLITITVRGRNVHMKQEHYMKGSDG------APDTGYLWHVPLTFITSKSDMVHRFLL 54 Query: 606 KSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHD 665 K+KTD L LPE+ W+KFNV NGYYIVHYE GWD L L HT + DR LI++ Sbjct: 55 KTKTDVLILPEEVEWIKFNVGMNGYYIVHYEDDGWDSLTGLLKGTHTAVSSNDRASLINN 114 Query: 666 VFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRY 725 FQLV G+L+++KALD++ YL+HET + +GL+ L Y +M++R+++++ K + Sbjct: 115 AFQLVSIGKLSIEKALDLSLYLKHETEIMPVFQGLNELIPMYKLMEKRDMNEVETQFKAF 174 Query: 726 LLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLN 785 L++ + +ID+Q+W+D+GSV +RMLRS LL LAC N+ PC+Q+A F +W ES+G L+ Sbjct: 175 LIRLLRDLIDKQTWTDEGSVSERMLRSQLLLLACVHNYQPCVQRAEGYFRKWKESNGNLS 234 Query: 786 IPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGM 845 +P DV V++VGAQ+T GW++L +Y+ S+SS E+++I +AL ++++EKL L++ Sbjct: 235 LPVDVTLAVFAVGAQSTEGWDFLYSKYQFSLSSTEKSQIEFALCRTQNKEKLQWLLDESF 294 Query: 846 EGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHF 905 +G IKTQ +L I R P G LAW F+R+NW L++KF+LGS I ++ GTT F Sbjct: 295 KGDKIKTQEFPQILTLIGRNPVGYPLAWQFLRKNWNKLVQKFELGSSSIAHMVMGTTNQF 354 Query: 906 SSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVN 959 S++ +L+EVK FF SL+ GS L Q +ETI +NI W++KN +R WL Sbjct: 355 STRTRLEEVKGFFSSLKENGSQLRCVQQTIETIEENIGWMDKNFDKIRVWLQSE 408 >1Z1W-A nrPDB Length = 780 Score = 557 bits (1435), Expect = e-159, Method: Composition-based stats. Identities = 202/821 (24%), Positives = 357/821 (43%), Gaps = 100/821 (12%) Query: 85 NLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPA 144 + D I+ N T+ I + D+ + LQ +MK +Y Sbjct: 2 EVEKYDLTLDFDIQKRTFNGTETITADAGDIVLDAVGLQIN----WMKVNGRDTAFTYDG 57 Query: 145 HEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQA 204 + P P + + F K+ D G Y G + T FE T A Sbjct: 58 Q---TVRAPGDSQPQ---KIEISFAGKVSDSLSGIY------YAGRENGMITTHFEATDA 105 Query: 205 RMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLV 264 R FPC D P +KA F+I + + + A+SNMP + E ++E F+ T +MSTYL+ Sbjct: 106 RRMFPCVDHPAYKAVFAITVVIDKDYDAISNMPPKRIEVSERKVVE--FQDTPRMSTYLL 163 Query: 265 AYIVCDF-HSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKL 323 + F + + + + + K ++ Y L + K ++FYE YF I Y L K+ Sbjct: 164 YVGIGKFRYEYEKYRD----IDLILASLKDIRSKYPLDMARKSVEFYENYFGIPYALPKM 219 Query: 324 DLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTM 383 LI++P+F GAMENWG IT+RE + + S+ + K VIAHE+AHQWFG+LVTM Sbjct: 220 HLISVPEFGAGAMENWGAITFREIYMDI-AENSAVTVKRNSANVIAHEIAHQWFGDLVTM 278 Query: 384 EWWNDIWLKEGFAKYMELIAVNATYPELQFD-DYFLNVCFEVITKDSLNSSRPISKPAET 442 +WWND+WL E FA +M ++ +PE F D+F++ + DSL ++ PI Sbjct: 279 KWWNDLWLNESFATFMSYKTMDTLFPEWSFWGDFFVSRTSGALRSDSLKNTHPIEVDVRD 338 Query: 443 PTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNS 502 P +I ++FDE+SY KGA IL M++D+ G E+F+KGI +YL + NA+ DLW+++ + Sbjct: 339 PDEISQIFDEISYGKGASILRMIEDYAGYEEFRKGISKYLNDHKFGNAEGSDLWTAIEDV 398 Query: 503 CLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQ 562 VK +M W G P++ +K++G + + Sbjct: 399 S---------------------------GKPVKRVMEYWIKNPGYPVIKLKRNGRKITMY 431 Query: 563 QERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVK 622 Q RFL +E+ W P+ + + + R +L+ + E +K Sbjct: 432 QTRFLLNG-EEEGRW-----------PVPVNIKKKDGVERILLEDEASI----EADGLIK 475 Query: 623 FNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRL-TLDKAL 681 N DS G+Y V Y+ D + + ++ L P DR+GL+ D+F + +G + Sbjct: 476 INADSAGFYRVLYD----DATFSDVMGHYRDLSPLDRIGLVDDLFAFLLSGHIDPETYRQ 531 Query: 682 DMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSD 741 + + E + + + +E + + + + + + Sbjct: 532 RIRNFFDDEDHNV-ITAIVGQMEYLRMLTHAFDDD---------ARAFCRSRMQFLTGKQ 581 Query: 742 KGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQT 801 ++ + R + L + D ++A + ++LF + + ++ + + A Sbjct: 582 DENLKIALGRVSRLYVMVDESYAE---EMSKLFKDFDSAE------PEMRSSIATAYALV 632 Query: 802 TAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHA 861 T LLE++ ++ +I+ A K L + + + + IK Q++ + + Sbjct: 633 TGDLKGLLEKFRSVDRDEDRVRIISAFGKLKSNTDLSTVYGMVEKTE-IKKQDMISFFSS 691 Query: 862 IARRPKGQQLAWDFVRENWT---HLLKKFDLGSYDIRMIIS 899 G+ +F+ N L+ ++ G+ + Sbjct: 692 ALETLPGR----EFIFANLDRIIRLVIRYFTGNRTASRTVE 728 >4Q4I-A nrPDB Length = 891 Score = 445 bits (1144), Expect = e-125, Method: Composition-based stats. Identities = 143/695 (20%), Positives = 244/695 (35%), Gaps = 100/695 (14%) Query: 117 ITNATLQSEEDSRYMKPGKELKVLSYPAH--------EQIALLVPEKLTPHLKYYVAMDF 168 ++ A D+ G++LK++S + E+ LV L + + Sbjct: 60 VSQAVRHGASDAPLRLNGEDLKLVSVHINDEPWTAWKEEEGALVISNLPERFTLKIINEI 119 Query: 169 QAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRES 228 EG Y+S T E R D P A F+ KI + Sbjct: 120 SPAANTALEGLYQSGDA---------LCTQCEAEGFRHITYYLDRPDVLARFTTKIIADK 170 Query: 229 --RHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGF--TSSGVKV 284 LSN +V ELE G ++ YL A + DF L T SG +V Sbjct: 171 IKYPFLLSNGNRVAQGELENGRHWVQWQDPFPKPCYLFALVAGDFDVLRDTFTTRSGREV 230 Query: 285 SI--YASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLI 342 ++ Y ++ +A+ + + + E+ F + Y L ++A+ F GAMEN GL Sbjct: 231 ALELYVDRGNLDRAPWAMTSLKNSMKWDEERFGLEYDLDIYMIVAVDFFNMGAMENKGLN 290 Query: 343 TYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYM--E 400 + +L T++ D L + RVI HE H W GN VT W + LKEG + E Sbjct: 291 IFNSKYVLARTDTATDKDYLDIERVIGHEYFHNWTGNRVTCRDWFQLSLKEGLTVFRDQE 350 Query: 401 LIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGAC 460 + + + ++ + +D+ + PI ++ + Y KGA Sbjct: 351 FSSDLGSRAVNRINNVRTMRGLQ-FAEDASPMAHPIRPDMV--IEMNNFYTLTVYEKGAE 407 Query: 461 ILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKM 520 ++ M+ LGEE FQKG+ Y ++ A DD ++ ++ + + H Sbjct: 408 VIRMIHTLLGEENFQKGMQLYFERHDGSAATCDDFVQAMEDAS------NVDLSH----- 456 Query: 521 TSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRAL 580 W Q G P++ VK D + E++ + Q P Sbjct: 457 -----------------FRRWYSQSGTPIVTVKDD---YNPETEQYTLTISQRTPATPDQ 496 Query: 581 QERYLWHIPLT---YSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYI----- 632 E+ HIP Y + + L++ + F+ N Y+ Sbjct: 497 AEKQPLHIPFAIELYDNEGKVIPLQKGGHPVNSVLNVTQAEQTFVFD---NVYFQPVPAL 553 Query: 633 -------VHYEGHGWDQLITQLNQNHT-LLRPKDRVGLIHDVF---QLVGAGR-----LT 676 V E DQ +T L ++ D + + + + L Sbjct: 554 LCEFSAPVKLEYKWSDQQLTFLMRHARNDFSRWDAAQSLLATYIKLNVARHQQGQPLSLP 613 Query: 677 LDKALDMTYYLQHETSSPAL------LEGLSYLESFYHMMDRRNISDISENLKRYLLQYF 730 + A L E PAL L ++ + + ++D I+++ E L R L Sbjct: 614 VHVADAFRAVLLDEKIDPALAAEILTLPSVNEMAELFDIIDPIAIAEVREALTRTLATEL 673 Query: 731 KPVI--------DRQSWSDKGSVWDRMLRSALLKL 757 + + + + R LR+A L+ Sbjct: 674 ADELLAIYNANYQSEYRVEHEDIAKRTLRNACLRF 708 >5DLL-A nrPDB Length = 867 Score = 417 bits (1072), Expect = e-116, Method: Composition-based stats. Identities = 123/494 (24%), Positives = 197/494 (39%), Gaps = 69/494 (13%) Query: 120 ATLQSEEDSRYMKPGKELKVLSYP--------------AHEQIALLVPEKLTPHLKYYVA 165 A ++ E++ + G ELK+LS ++ I VPEK L+ V Sbjct: 52 ANRENRENNTLVLDGVELKLLSIKLNNKHLSPAEFAVNENQLIINNVPEKFV--LQTVVE 109 Query: 166 MDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIR 225 ++ A EG YKS + T E T R D P A F++KI Sbjct: 110 INPSAN--TSLEGLYKSGD---------VFSTQCEATGFRKITYYLDRPDVMAAFTVKII 158 Query: 226 RES--RHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSG--FTSSG 281 + I LSN K+ + ++ ++ K YL A + D S+ T S Sbjct: 159 ADKKKYPIILSNGDKIDSGDISDNQHFAVWKDPFKKPCYLFALVAGDLASIKDTYITKSQ 218 Query: 282 VKVS--IYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENW 339 KVS IYA ++ HYA+QA + + E F + Y L ++A+PDF GAMEN Sbjct: 219 RKVSLEIYAFKQDIDKCHYAMQAVKDSMKWDEDRFGLEYDLDTFMIVAVPDFNAGAMENK 278 Query: 340 GLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYM 399 GL + ++ KT++ D V V+ HE H W G+ VT W + LKEG + Sbjct: 279 GLNIFNTKYIMASNKTATDKDFELVQSVVGHEYFHNWTGDRVTCRDWFQLSLKEGLTVFR 338 Query: 400 --ELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNK 457 E + + + DD + + +D+ S PI E+ ++ + YNK Sbjct: 339 DQEFTSDLNSRDVKRIDDVRI-IRSAQFAEDASPMSHPIR--PESYIEMNNFYTVTVYNK 395 Query: 458 GACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSD 517 GA I+ M+ LGEE FQKG+ Y ++ + DD ++++++ Sbjct: 396 GAEIIRMIHTLLGEEGFQKGMKLYFERHDGQAVTCDDFVNAMADANNRDF---------- 445 Query: 518 PKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEW 577 + W Q G P + V ++ + + + Q Sbjct: 446 ------------------SLFKRWYAQSGTPNIKVSEN---YDASSQTYSLTLEQTTLPT 484 Query: 578 RALQERYLWHIPLT 591 +E+ HIP+ Sbjct: 485 ADQKEKQALHIPVK 498 >4QHP-A nrPDB Length = 870 Score = 403 bits (1035), Expect = e-112, Method: Composition-based stats. Identities = 110/563 (19%), Positives = 200/563 (35%), Gaps = 74/563 (13%) Query: 69 LPSVVIPLHYDLF--VHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEE 126 L P ++ L +H ++ V ++ V + ++L ++ + + Sbjct: 11 LKDYQTPAYHILKTDLHFDINEPQTVVKSRLTVEPQRVGEPLVLD-GSAKLLSVKINGAA 69 Query: 127 DSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRT 186 Y+ G+ L + P+ V + G Y S Sbjct: 70 AD-YVLEGETLTIAGVPS-------------ERFTVEVETEILPAENKSLMGLYAS---- 111 Query: 187 LGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRES--RHIALSNMPKVKTIEL 244 GG T EP R D P + F+ I + + LSN K+ E Sbjct: 112 -GGN----LFTQCEPEGFRKITFYIDRPDVMSKFTTTIVADKKRYPVLLSNGNKIDGGEF 166 Query: 245 EGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGF----TSSGVKVSIYASPDKRNQTHYAL 300 G +E +YL A + D + + VK+ Y + + + +A+ Sbjct: 167 SDGRHWVKWEDPFSKPSYLFALVAGDLAVTEDYFTTMSGRNVKIEFYTTEADKPKVGFAV 226 Query: 301 QASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASD 360 ++ + + E F + Y L ++A+ DF GAMEN GL + +L D +T++ +D Sbjct: 227 ESLKNAMKWDETRFGLEYDLDIFMVVAVGDFNMGAMENKGLNIFNTKFVLADSRTATDTD 286 Query: 361 KLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYM--ELIAVNATYPELQFDDYFL 418 + V+ HE H W GN VT W + LKEG + E A+ + ++ L Sbjct: 287 FEGIESVVGHEYFHNWTGNRVTCRDWFQLSLKEGLTVFRDQEFSGDRASRAVRRIENIRL 346 Query: 419 NVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGI 478 + +D+ ++ P+ + ++ + Y KGA ++ M LGEE FQKG+ Sbjct: 347 -LRQHQFPEDAGPTAHPVR--PASYEEMNNFYTMTVYEKGAEVVRMYHTLLGEEGFQKGM 403 Query: 479 IQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMM 538 Y ++ + DD ++++++ + + Sbjct: 404 KLYFQRHDGQAVTCDDFRAAMADANGINL----------------------------DQF 435 Query: 539 TTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSN 598 W Q G P+L RL+ F V Q P + ++ IP+ + N Sbjct: 436 ALWYSQAGTPVLE-----AEGRLKNNIFELTVKQTVPPTPDMTDKQPMMIPVKVGLLNRN 490 Query: 599 V----IHRHILKSKTDTLDLPEK 617 ++ L L E Sbjct: 491 GEAVAFDYQGKRATEAVLLLTEA 513 >4GAA-A nrPDB Length = 609 Score = 389 bits (998), Expect = e-108, Method: Composition-based stats. Identities = 99/436 (22%), Positives = 171/436 (39%), Gaps = 36/436 (8%) Query: 70 PSVVIPLHYDLFVHPNLTSLDFVASEKIEVL-VSNATQFIILHSKDLEITNATLQSEEDS 128 P H L +H + TS AS + V + ++ +IL +KDL I + ++ + Sbjct: 10 PEKFNIKHMHLKLHVDFTSRAIAASTSLTVRSLQDSLASLILDTKDLTIKKVAVNGKDAT 69 Query: 129 RYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMD-FQAKLGDGFEGFYKSTYRTL 187 + K + + +P LT + V +D + + K Sbjct: 70 FALGTTHSFK------GTPLEITLPFSLTRGQEVIVEIDSVTSPKSSALQWLNK---EQT 120 Query: 188 GGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGG 247 G+ + + T R PC D P K + ++ +AL M ++ EL Sbjct: 121 AGKIHPYLFSQCQATHCRSIIPCQDTPSVKFTYYSQVSVPKELMAL--MSALRDGELSEQ 178 Query: 248 LLEDH----FETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQAS 303 + F+ V + +YL+A +V G + +I+ + + Y + Sbjct: 179 SDSNRKIYRFKQNVPIPSYLIALVVGALEG----RKVGPRTTIWTEKELLEPSVYEFAET 234 Query: 304 LKLLDFYEKYFDIYYPLSKLDLIAIPD-FAPGAMENWGLITYRETSLLFDPKTSSASDKL 362 K+L + E Y + DL+ +P F G MEN L T L D +S Sbjct: 235 EKMLKYAEDLAG-PYVWGQYDLLILPPSFPYGGMENPCLTFVTPTVLAGDRSLAS----- 288 Query: 363 WVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCF 422 VIAHE++H W GNLVT E W + WL EG Y+E Y E L Sbjct: 289 ----VIAHEISHSWTGNLVTNETWENFWLNEGHTVYLERRIDGRLYGEEFRQFKALGGWK 344 Query: 423 EVITK-DSLNSSRPISK--PAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGII 479 E+ ++ ++ P++ P + F V Y KG +L L+ LG + G + Sbjct: 345 ELQNSVNTFGATNPLTNLVPNLHEVDVDAAFSSVPYEKGFALLFYLEQLLGGPEIFLGFL 404 Query: 480 Q-YLKKFSYRNAKNDD 494 + Y++ F++++ ++ Sbjct: 405 KSYIQMFAFKSVTTEE 420 >5FWQ-A nrPDB Length = 633 Score = 369 bits (947), Expect = e-102, Method: Composition-based stats. Identities = 97/432 (22%), Positives = 172/432 (39%), Gaps = 32/432 (7%) Query: 77 HYDLFVHPNLTSLDFVASEKIEVLVS-NATQFIILHSKDLEITNATLQSEEDSRYMKPGK 135 H L + T + + V + + ++L +KDL I + +E + + Sbjct: 35 HLHLRCSVDFTRRTLTGTAALTVQSQEDNLRSLVLDTKDLTIEKVVINGQEVKYALGERQ 94 Query: 136 ELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDF-QAKLGDGFEGFYKSTYRTLGGETRIL 194 K + + +P L+ + + + + F + + T G+ Sbjct: 95 SYK------GSPMEISLPIALSKNQEIVIEISFETSPKSSALQWL---TPEQTSGKEHPY 145 Query: 195 AVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIAL-SNMPKVKTIELEGGLLEDH- 252 + + R PC D P K ++ ++ +AL S + +T + E + + Sbjct: 146 LFSQCQAIHCRAILPCQDTPSVKLTYTAEVSVPKELVALMSAIRDGETPDPEDPSRKIYK 205 Query: 253 FETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEK 312 F V + YL+A +V S G + +++ ++ ++ Y + +L E Sbjct: 206 FIQKVPIPCYLIALVVGALES----RQIGPRTLVWSEKEQVEKSAYEFSETESMLKIAED 261 Query: 313 YFDIYYPLSKLDLIAIPD-FAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHE 371 Y + DL+ +P F G MEN L T+ +LL A DK ++ VIAHE Sbjct: 262 LGG-PYVWGQYDLLVLPPSFPYGGMENPCL-TFVTPTLL-------AGDKS-LSNVIAHE 311 Query: 372 LAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITK-DSL 430 ++H W GNLVT + W+ WL EG Y+E + E L E+ + Sbjct: 312 ISHSWTGNLVTNKTWDHFWLNEGHTVYLERHICGRLFGEKFRHFNALGGWGELQNSVKTF 371 Query: 431 NSSRPISKPAETPTQIQE--MFDEVSYNKGACILNMLKDFLGEEKFQKGIIQ-YLKKFSY 487 + P +K T I + V Y KG +L L+ LG + G ++ Y++KFSY Sbjct: 372 GETHPFTKLVVDLTDIDPDVAYSSVPYEKGFALLFYLEQLLGGPEIFLGFLKAYVEKFSY 431 Query: 488 RNAKNDDLWSSL 499 ++ DD L Sbjct: 432 KSITTDDWKDFL 443 >5Y1X-A nrPDB Length = 914 Score = 366 bits (938), Expect = e-101, Method: Composition-based stats. Identities = 158/878 (17%), Positives = 305/878 (34%), Gaps = 127/878 (14%) Query: 51 GAFPVATNGERFPWQELRL---PSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQF 107 G P ++ P R PS I + L ++ + + +++ N + Sbjct: 13 GLVPRGSHMASEPKIHYRKDYKPSGFIINNVTLNINIHDNETIVRSVLDMDISKHNVGED 72 Query: 108 IILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMD 167 ++ L+I ++ +++ + G+E +E + + + + Sbjct: 73 LVFDGVGLKINEISINNKK----LVEGEEYTY----DNEFLTIFSKFVPKSKFAFSSEVI 124 Query: 168 FQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRE 227 + G YKS + + V+ E T R D P A + + + + Sbjct: 125 IHPETNYALTGLYKS---------KNIIVSQCEATGFRRITFFIDRPDMMAKYDVTVTAD 175 Query: 228 S--RHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLS-----GFTSS 280 + LSN KV E+ GG F YL A + D LS +T Sbjct: 176 KEKYPVLLSNGDKVNEFEIPGGRHGARFNDPHLKPCYLFAVVAGDLKHLSATYITKYTKK 235 Query: 281 GVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWG 340 V++ +++ ++ +AL+ K + F E YF + Y LS+L+L+A+ DF GAMEN G Sbjct: 236 KVELYVFSEEKYVSKLQWALECLKKSMAFDEDYFGLEYDLSRLNLVAVSDFNVGAMENKG 295 Query: 341 LITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYME 400 L + SLL K S + V+ HE H + GN VT+ W + LKEG + E Sbjct: 296 LNIFNANSLLASKKNSIDFSYARILTVVGHEYFHNYTGNRVTLRDWFQLTLKEGLTVHRE 355 Query: 401 LI----AVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAE--TPTQIQEMFDEVS 454 + L D +V F L S P+S P + ++ + Sbjct: 356 NLFSEEMTKTVTTRLSHVDLLRSVQF-------LEDSSPLSHPIRPESYVSMENFYTTTV 408 Query: 455 YNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVC 514 Y+KG+ ++ M LGEE ++KG Y+KK A +D ++ + + Sbjct: 409 YDKGSEVMRMYLTILGEEYYKKGFDIYIKKNDGNTATCEDFNYAMEQAYKMKKADNSANL 468 Query: 515 HSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQED 574 + W Q G P + K + +++++ V Q Sbjct: 469 NQYLL---------------------WFSQSGTPHVSFKYN---YDAEKKQYSIHVNQYT 504 Query: 575 PEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSN------ 628 +E+ IP++ + I S+T E ++V N+ Sbjct: 505 KPDENQKEKKPLFIPISVGLINPENGKEMI--SQTTLELTKESDTFVFNNIAVKPIPSLF 562 Query: 629 -GYYIVHYEGHGW--DQLITQLNQNHTLLRPKDRVGLI--------HDVFQLVGAGRL-- 675 G+ Y ++ I L + + I ++ F +L Sbjct: 563 RGFSAPVYIEDNLTDEERILLLKYDSDAFVRYNSCTNIYMKQILMNYNEFLKAKNEKLES 622 Query: 676 ----TLDKAL-DMTYYLQHETS----SPALLEGLSYLESFYHMMDRRNISDISENLKRYL 726 ++ D YL + + + L + + + +D+ + K Y+ Sbjct: 623 FNLTPVNAQFIDAIKYLLEDPHADAGFKSYIVSLPQDRYIINFVSNLD-TDVLADTKEYI 681 Query: 727 LQY---------------FKPVIDRQSWSDKGSVWD------RMLRSALLKLACDLNHAP 765 + + D ++ + S D R LR+ LL L + Sbjct: 682 YKQIGDKLNDVYYKMFKSLEAKADDLTYFNDESHVDFDQMNMRTLRNTLLSLLSKAQYPN 741 Query: 766 CIQKA-----AELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAE 820 + + + S W+ S ++ D +Y + + LL+++ ++S ++ Sbjct: 742 ILNEIIEHSKSPYPSNWLTSL-SVSAYFDKYFELYDKTYKLSKDDELLLQEWLKTVSRSD 800 Query: 821 QNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAAL 858 + I L ++ ++++ I+ L Sbjct: 801 RKDIYEIL-----KKLENEVLKDSKNPNDIRAVYLPFT 833 >5ZI5-A nrPDB Length = 921 Score = 325 bits (834), Expect = 4e-89, Method: Composition-based stats. Identities = 109/550 (19%), Positives = 202/550 (36%), Gaps = 73/550 (13%) Query: 40 VPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEV 99 VP H G F + + + + +H DL + +L+ + ++ V Sbjct: 15 VPRGSHMMVKQGVFMKTDQSKVKKLSDYKSLDYFV-IHVDLQI--DLSKKPVESKARLTV 71 Query: 100 LVSNATQFIILHSKDLEIT--NATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLT 157 + + HS DL + N TL S + + + E ++ L+ + + Sbjct: 72 V---PNLNVDSHSNDLVLDGENMTLVSLQMNDNLLKENEYELTKDS-------LIIKNIP 121 Query: 158 PHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFK 217 + + + M G Y ET +A+ E R F D P Sbjct: 122 QNTPFTIEMTSLLGENTDLFGLY---------ETEGVALVKAESEGLRRVFYLPDRPDNL 172 Query: 218 ANFSIKIR--RESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLS 275 A + I +E + LSN ++ EL GL + V +YL A + + Sbjct: 173 ATYKTTIIANQEDYPVLLSNGVLIEKKELPLGLHSVTWLDDVPKPSYLFALVAGNLQRSV 232 Query: 276 GF--TSSGVKVSI--YASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDF 331 + T SG ++ I Y P ++ +A + + + + E+ F++ L + + + + Sbjct: 233 TYYQTKSGRELPIEFYVPPSATSKCDFAKEVLKEAMAWDERTFNLECALRQHMVAGVDKY 292 Query: 332 APGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWL 391 A GA E GL + +L P+T + L V V+AHE H W G+ VT+ W ++ L Sbjct: 293 ASGASEPTGLNLFNTENLFASPETKTDLGILRVLEVVAHEFFHYWSGDRVTIRDWFNLPL 352 Query: 392 KEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFD 451 KEG + A + E + F ++ +L+ P T ++ ++ Sbjct: 353 KEGLTTFRA-----AMFRE----ELFGTDLIRLLDGKNLDERAPRQSA---YTAVRSLYT 400 Query: 452 EVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSG 511 +Y K A I M+ F+G+E F + + ++ K +D S+SNS + Sbjct: 401 AAAYEKSADIFRMMMLFIGKEPFIEAVAKFFKDNDGGAVTLEDFIESISNSSGKDL---- 456 Query: 512 GVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVF 571 +W + GIP L+V L +++ + Sbjct: 457 ------------------------RSFLSWFTESGIPELIVTD---ELNPDTKQYFLKIK 489 Query: 572 QEDPEWRALQ 581 + R + Sbjct: 490 TVNGRNRPIP 499 >3CIA-A nrPDB Length = 605 Score = 307 bits (786), Expect = 2e-83, Method: Composition-based stats. Identities = 96/438 (21%), Positives = 165/438 (37%), Gaps = 38/438 (8%) Query: 71 SVVIPLHYDLFVHPNLTSLDFVASEKIEVLVS-NATQFIILHSKDLEITNATLQSEEDSR 129 V H L ++ + ++ + + +IL ++DL I + + Sbjct: 24 DQVKATHVYLDLNVDFDKKSLSGFAELSLDWFTDNKAPLILDTRDLVIHRV-MAKNSQGQ 82 Query: 130 YMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGG 189 ++K +L ++ + P YY + G + + G Sbjct: 83 WVKVNYDLAKRDDVLGSKLTINTPLNAKKVRVYY----NSTEKATGLQWL---SAEQTAG 135 Query: 190 ETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLL 249 + + + + AR P D P + ++ +I + +A+ + E +G Sbjct: 136 KEKPFLFSQNQAIHARSWIPIQDTPSVRVTYTARITTDKDLLAVMSANNEPGTERDGDYF 195 Query: 250 EDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDF 309 F + YL+A V D F + + IYA + + ++D Sbjct: 196 ---FSMPQAIPPYLIAIGVGDLE----FKAMSHQTGIYAESYILDAAVAEFDDTQAMIDK 248 Query: 310 YEKYFDIYYPLSKLDLIAIPD-FAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVI 368 E+ + Y + DL+ +P F G MEN L F T A DK V +I Sbjct: 249 AEQMYG-KYRWGRYDLLMLPPSFPFGGMEN--------PRLSFITPTVVAGDKSLV-NLI 298 Query: 369 AHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYP------ELQFDDYFLNVCF 422 AHELAH W GNLVT E W D+WL EGF Y+E + A + E LN Sbjct: 299 AHELAHSWSGNLVTNESWRDLWLNEGFTSYVENRIMEAVFGTDRAVMEQALGAQDLNA-- 356 Query: 423 EVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYL 482 E++ D+ ++ I P + F V Y KG L L++ G E+F +++Y Sbjct: 357 EILELDASDTQLYIDLKGRDP---DDAFSGVPYVKGQLFLMYLEEKFGRERFDAFVLEYF 413 Query: 483 KKFSYRNAKNDDLWSSLS 500 ++++ D+ L Sbjct: 414 DSHAFQSLGTDNFVKYLK 431 >2XPY-A nrPDB Length = 632 Score = 290 bits (742), Expect = 2e-78, Method: Composition-based stats. Identities = 104/539 (19%), Positives = 180/539 (33%), Gaps = 64/539 (11%) Query: 76 LHYDLFVHPNLTSLDFVASEKIEVLV----SNATQFIILHSKDLEITNATLQSEEDSRYM 131 LH DL + + S ++ N + + L + L++ + + + Sbjct: 31 LHTDLNLSVSFEKSAISGSVTFQLKKLHEGKNKSDELHLDTSYLDVQEVHIDGSKADFQI 90 Query: 132 KPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDF-QAKLGDGFEGFYKSTYRTLGGE 190 + KE P ++ + + + + + + F + + +T GG Sbjct: 91 EQRKE------PLGSRLVIN---NASCNDNFTLNIQFRTTDKCTALQWLN--SKQTKGG- 138 Query: 191 TRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLE 250 + + E AR FPCFD P K+ F+ I + S ++ + Sbjct: 139 -KPYVFSQLEAIHARSLFPCFDTPSVKSTFTASIESPL-PVVFSG---IRIEDTSKDTNI 193 Query: 251 DHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFY 310 FE V + YL+ D S G + ++Y P + + + ++ Sbjct: 194 YRFEQKVPIPAYLIGIASGDLSS----APIGPRSTVYTEPFRLKDCQWEFENDVEKFIQT 249 Query: 311 EKYFDIYYPLSKLDLIA-IPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIA 369 + Y D++ + + G ME+ ++ F T A D+ + VIA Sbjct: 250 AEKIIFEYEWGTYDILVNVDSYPYGGMES--------PNMTFATPTLIAHDRSNID-VIA 300 Query: 370 HELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDS 429 HELAH W GNLVT WN WL EG+ Y+E + A + E L + D Sbjct: 301 HELAHSWSGNLVTNCSWNHFWLNEGWTVYLERRIIGAIHGEPTRHFSAL-----IGWSDL 355 Query: 430 LNSSRPISKPAETPTQIQEM---------FDEVSYNKGACILNMLKDFL-GEEKFQKGII 479 NS + P T +Q + F V Y KG +L L+ L G+ +F I Sbjct: 356 QNSIDSMKDPERFSTLVQNLNDNTDPDDAFSTVPYEKGFNLLFHLETILGGKAEFDPFIR 415 Query: 480 QYLKKFSYRNAKNDDLWSSLSNSCLES----DFTSGGVCHSDPKMTSNMLAFLGENAEVK 535 Y KKF+ ++ +L E D P M V Sbjct: 416 HYFKKFAKKSLDTFQFLDTLYEFYPEKKEILDSVDWETWLYKPGMPPRPHFITALADNVY 475 Query: 536 EMMTTWTLQKGIPLLVVKQ--------DGCSLRLQQERFLQGVFQEDPEWRALQERYLW 586 ++ W + L + D Q ++ + + W Sbjct: 476 QLADKWV-EMAQHLKTTEDFRSEFNAIDIKDFNSNQLVLFLETLTQNGHSNKKPKDFDW 533 >4FGM-A nrPDB Length = 597 Score = 37.1 bits (84), Expect = 0.034, Method: Composition-based stats. Identities = 28/159 (17%), Positives = 52/159 (32%), Gaps = 32/159 (20%) Query: 340 GLITYRETSLLFDPKTSSAS-------DKLWVTRVIAHELAHQWFGNLVTME-------- 384 GL T+LL K ++ + + HE H W N+ T++ Sbjct: 236 GLEHRNSTALLCSRKDLISAHQYEMNDNYQTFLSLCCHEYFHSW--NIKTLKPKAFLPYQ 293 Query: 385 -----WWNDIWLKEGFAKYMELIAVNA--TYPELQFDDYFLNVCFEV-----ITKDSLNS 432 + +W EG Y + ++ E ++ + V + S+ Sbjct: 294 LEKESYTEQLWFYEGMTSYFDDYLLHTSGIIDEKRYLKLLGDTLSRVERGAGQYQQSVTE 353 Query: 433 SRPISKPAETPTQIQEMFDEVS--YNKGACILNMLKDFL 469 S ++ + Q + + + Y KGA I L L Sbjct: 354 SSFLAWT-KFYQQNENAPNSIVSYYAKGALIALSLDLML 391 >4WNR-A nrPDB Length = 349 Score = 34.8 bits (78), Expect = 0.21, Method: Composition-based stats. Identities = 22/145 (15%), Positives = 58/145 (40%), Gaps = 7/145 (4%) Query: 818 SAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLA---WD 874 E +L + L +L+ G +G +TQ + + + K +++ WD Sbjct: 39 LNEVKVLLVGDGEAGKTSLLKRLLGEGFDGNEHQTQGIN--IKKWGFKDKDKEIKVNFWD 96 Query: 875 FVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTV 934 F + H +F L + +++ + ++ L+ ++ F + I + Sbjct: 97 FGGQEIMHATHQFFLSKRSLYILVLDSRRDEKAEYWLKHIRSFGGDSPVLVALNKIDEN- 155 Query: 935 LETITKNIKWLEKNLPTLRTWLMVN 959 + N K+L++ P+++ + ++ Sbjct: 156 -PSFELNRKFLQEKYPSIKGFFRIS 179 >3ZUK-A nrPDB Length = 699 Score = 34.4 bits (77), Expect = 0.22, Method: Composition-based stats. Identities = 16/48 (33%), Positives = 23/48 (47%), Gaps = 11/48 (22%) Query: 350 LFDPKTSSASDKLWVTRVIAHELAHQW---------FGNLVTMEWWND 388 FDP+ A++ + VI HE+ H + GNLV +WW D Sbjct: 509 FFDPQADEAANYGGIGAVIGHEIGHGFDDQGAKYDGDGNLV--DWWTD 554 >2C4R-L nrPDB Length = 517 Score = 33.6 bits (75), Expect = 0.45, Method: Composition-based stats. Identities = 20/100 (20%), Positives = 41/100 (41%), Gaps = 6/100 (6%) Query: 225 RRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKV 284 R++ ++LS + ++ L+ E H V +++YL+ +++ GV+ Sbjct: 420 VRDNESLSLSILRLIEEEALKENTQEVHAIVPVPIASYLLNEKRSAVNAIE-TRQDGVRC 478 Query: 285 SIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLD 324 + D+ HY + K E+ + Y L KL Sbjct: 479 -VIVPNDQMETPHYHVLRVRKG----EETPTLSYMLPKLH 513 >3MDV-A nrPDB Length = 456 Score = 32.9 bits (73), Expect = 0.74, Method: Composition-based stats. Identities = 14/72 (19%), Positives = 27/72 (37%) Query: 409 PELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDF 468 D FL+ + +N S +P +++ YNK + + L+ Sbjct: 8 GGRVLQDVFLDWAKKYGPVVRVNVFHKTSVIVTSPESVKKFLMSTKYNKDSKMYRALQTV 67 Query: 469 LGEEKFQKGIIQ 480 GE F +G++ Sbjct: 68 FGERLFGQGLVS 79 >4AKR-A nrPDB Length = 281 Score = 32.9 bits (73), Expect = 0.79, Method: Composition-based stats. Identities = 27/79 (34%), Positives = 33/79 (41%), Gaps = 3/79 (3%) Query: 624 NVDSNGYYIV--HYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKAL 681 NV SNG V HY G QL T + Q T D + F+ +G L L AL Sbjct: 181 NVTSNGKVQVNVHYFEDGNVQLNT-VTQKQTTSPSADAQSTAVNAFKAIGKAELNLHTAL 239 Query: 682 DMTYYLQHETSSPALLEGL 700 D Y +T+ AL L Sbjct: 240 DNNYSTMGDTTFKALRRAL 258 >4DDQ-A nrPDB Length = 502 Score = 31.7 bits (70), Expect = 1.6, Method: Composition-based stats. Identities = 23/141 (16%), Positives = 48/141 (34%), Gaps = 9/141 (6%) Query: 70 PSVVIPLHYDLFVHPNL-TSLDFVASEKIEVLVSNATQFIILHSK-DLEITNATLQSEED 127 P + IP ++ P+ T+ + I + I + +K ++E T++ + Sbjct: 202 PDITIPELMEVIPGPDFPTAGQILGRSGIRKAYESGRGSITIRAKAEIEQTSSGKERIIV 261 Query: 128 SRYMKPGKELKVLS-------YPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFY 180 + + K++ E I L E ++ + + A Y Sbjct: 262 TELPYQVNKAKLIEKIADLVRDKKIEGITDLRDESDRTGMRIVIEIRRDANANVILNNLY 321 Query: 181 KSTYRTLGGETRILAVTDFEP 201 K T +LA+ D +P Sbjct: 322 KQTALQTSFGINLLALVDGQP 342 >4XBH-A nrPDB Length = 696 Score = 31.7 bits (70), Expect = 1.6, Method: Composition-based stats. Identities = 12/52 (23%), Positives = 20/52 (38%), Gaps = 11/52 (21%) Query: 350 LFDPKTSSASDKLWVTRVIAHELAH---------QWFGNLVTMEWWNDIWLK 392 F + S++ + + VI HE+ H G+LV +WW Sbjct: 510 FFSAQQSNSLNYGGIGMVIGHEITHGFDDNGRNFNKDGDLV--DWWTQQSAN 559 >1XMD-A nrPDB Length = 612 Score = 30.5 bits (67), Expect = 3.8, Method: Composition-based stats. Identities = 12/58 (20%), Positives = 26/58 (44%), Gaps = 7/58 (12%) Query: 901 TTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMV 958 + F+++D+ ++ + + + G+ + Q +LE WLE+ WL V Sbjct: 38 SVKPFANEDEYKKTEEIVQKFQE-GAGKRLHQKLLERARGKRNWLEE------WWLNV 88 >6DRU-A nrPDB Length = 718 Score = 30.2 bits (66), Expect = 5.2, Method: Composition-based stats. Identities = 48/280 (17%), Positives = 87/280 (31%), Gaps = 17/280 (6%) Query: 552 VKQDGCSLRLQQERF-LQGVFQEDPEWRALQERYLWHIPLTYS----TSSSNVIHRHILK 606 V DG L E L+ + W + + + + H++ Sbjct: 102 VNDDGSETLLTNEYAPLKSLNPRYYYWPGPGAEFSAEFSFSATPDEQIYGTGTQQDHMIN 161 Query: 607 SKTDTLDLPEKTSWVKFNVDSN--GYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIH 664 K +D+ S++ V + GY + L T L+ Sbjct: 162 KKGSVIDMVNFNSYIPTPVFMSNKGYAFIWNMPAEGRMEFGTLRTRFTAAST----TLVD 217 Query: 665 DVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKR 724 + +V A D L +P L Y++S ++ + +++N Sbjct: 218 --YVIVAAQPGDYDTLQQRISALTGRAPAPPDFS-LGYIQSKLRYENQTEVELLAQNFHD 274 Query: 725 YLLQYFKPVIDRQSWSDKGS--VWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSG 782 + VID QSW+ +G + R+ + A N A+ S +S Sbjct: 275 RNIPVSMIVIDYQSWAHQGDWALDPRLWPNVAQMSARVKNLTGAEMMASLWPSVADDSVN 334 Query: 783 KLNIPTDVLKIVYSVGAQTTAGWNYLL-EQYELSMSSAEQ 821 + + L G TT WN Y+ + SA + Sbjct: 335 YAALQANGLLSATRDGPGTTDSWNGSYIRNYDSTNPSARK 374 >1W8I-A nrPDB Length = 156 Score = 29.8 bits (65), Expect = 5.3, Method: Composition-based stats. Identities = 20/105 (19%), Positives = 38/105 (36%), Gaps = 4/105 (3%) Query: 398 YMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNK 457 ++ ++ T L++ + E + + + E E+F Y K Sbjct: 40 FVTNHILDETLTLLKYKKLPADKFLEGFVESGVLNIIYTDDEVERKAL--EVFKARVYEK 97 Query: 458 GACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNS 502 G + + + + EE + +I Y +FS D W SL S Sbjct: 98 GFSYTDAISEVVAEE-LKLKLISYDSRFSLPTIG-RDYWKSLDES 140 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.310 0.122 0.321 Lambda K H 0.267 0.0370 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 33,076,431 Number of Sequences: 36641 Number of extensions: 1223467 Number of successful extensions: 3647 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 38 Number of HSP's successfully gapped in prelim test: 20 Number of HSP's that attempted gapping in prelim test: 3413 Number of HSP's gapped (non-prelim): 73 length of query: 960 length of database: 10,336,785 effective HSP length: 106 effective length of query: 854 effective length of database: 6,452,839 effective search space: 5510724506 effective search space used: 5510724506 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.4 bits) S2: 64 (29.4 bits)