BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q6NVY1 (386 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 3BPT-A nrPDB 733 0.0 4HDT-A nrPDB 224 6e-59 4J2U-A nrPDB 220 9e-58 5MRE-88 nrPDB 192 2e-49 3JU1-A nrPDB 185 3e-47 5ZAI-A nrPDB 104 6e-23 5Z7R-A nrPDB 100 1e-21 2HW5-A nrPDB 97 1e-20 3H81-A nrPDB 97 1e-20 2DUB-A nrPDB 94 8e-20 4ZU2-A nrPDB 87 1e-17 5WYB-B nrPDB 83 2e-16 5YLO-A nrPDB 80 2e-15 3MOY-A nrPDB 78 7e-15 4JWV-A nrPDB 77 1e-14 6IUM-B nrPDB 71 8e-13 4FZW-A nrPDB 71 9e-13 5VE2-A nrPDB 70 1e-12 3T88-A nrPDB 70 2e-12 2IEX-A nrPDB 69 3e-12 5KJP-A nrPDB 65 4e-11 4FZW-C nrPDB 65 7e-11 5JBW-A nrPDB 63 2e-10 5ZRV-A nrPDB 62 4e-10 4JFC-A nrPDB 60 1e-09 4IZC-A nrPDB 60 1e-09 4JCS-A nrPDB 60 2e-09 3HIN-A nrPDB 60 2e-09 1NZY-B nrPDB 59 3e-09 2UZF-A nrPDB 59 4e-09 3ZWA-A nrPDB 59 4e-09 4EML-A nrPDB 58 9e-09 2D3T-A nrPDB 57 1e-08 2VSU-C nrPDB 54 8e-08 3HE2-A nrPDB 49 4e-06 2A81-A nrPDB 49 4e-06 6OJM-A nrPDB 47 1e-05 2PPY-A nrPDB 47 1e-05 3OME-A nrPDB 46 3e-05 2WTB-A nrPDB 46 3e-05 3T8B-A nrPDB 44 8e-05 3I47-A nrPDB 44 1e-04 4JSB-A nrPDB 44 2e-04 1EF9-A nrPDB 43 3e-04 3HP0-A nrPDB 42 3e-04 4Q1J-A nrPDB 36 0.022 3M6N-A nrPDB 35 0.067 4B3J-A nrPDB 33 0.28 2NP9-A nrPDB 32 0.32 4HC8-A nrPDB 32 0.55 5E7G-A nrPDB 30 1.2 3D31-A nrPDB 30 1.2 3GON-A nrPDB 30 1.7 5AYN-A nrPDB 30 1.9 1XX4-A nrPDB 29 2.8 3GYX-A nrPDB 29 2.8 2J49-A nrPDB 29 4.3 6DBY-A nrPDB 28 6.0 5BPW-A nrPDB 28 7.0 4MOW-A nrPDB 28 8.5 6BYQ-A nrPDB 28 8.6 1GEE-A nrPDB 28 8.8 >3BPT-A nrPDB Length = 363 Score = 733 bits (1891), Expect = 0.0, Method: Compositional matrix adjust. Identities = 354/355 (99%), Positives = 354/355 (99%) Query: 32 TDAAEEVLLEKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGG 91 TDAAEEVLL KKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGG Sbjct: 2 TDAAEEVLLGKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGG 61 Query: 92 KAFCAGGDIRVISEAEKAKQKIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLS 151 KAFCAGGDIRVISEAEKAKQKIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLS Sbjct: 62 KAFCAGGDIRVISEAEKAKQKIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLS 121 Query: 152 VHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGKLGYFLALTGFRLKGRDVYRAG 211 VHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGKLGYFLALTGFRLKGRDVYRAG Sbjct: 122 VHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGKLGYFLALTGFRLKGRDVYRAG 181 Query: 212 IATHFVDSEKLAMLEEDLLALKSPSKENIASVLENYHTESKIDRDKSFILEEHMDKINSC 271 IATHFVDSEKLAMLEEDLLALKSPSKENIASVLENYHTESKIDRDKSFILEEHMDKINSC Sbjct: 182 IATHFVDSEKLAMLEEDLLALKSPSKENIASVLENYHTESKIDRDKSFILEEHMDKINSC 241 Query: 272 FSANTVEEIIENLQQDGSSFALEQLKVINKMSPTSLKITLRQLMEGSSKTLQEVLTMEYR 331 FSANTVEEIIENLQQDGSSFALEQLKVINKMSPTSLKITLRQLMEGSSKTLQEVLTMEYR Sbjct: 242 FSANTVEEIIENLQQDGSSFALEQLKVINKMSPTSLKITLRQLMEGSSKTLQEVLTMEYR 301 Query: 332 LSQACMRGHDFHEGVRAVLIDKDQSPKWKPADLKEVTEEDLNNHFKSLGSSDLKF 386 LSQACMRGHDFHEGVRAVLIDKDQSPKWKPADLKEVTEEDLNNHFKSLGSSDLKF Sbjct: 302 LSQACMRGHDFHEGVRAVLIDKDQSPKWKPADLKEVTEEDLNNHFKSLGSSDLKF 356 >4HDT-A nrPDB Length = 353 Score = 224 bits (570), Expect = 6e-59, Method: Compositional matrix adjust. Identities = 132/345 (38%), Positives = 193/345 (55%), Gaps = 12/345 (3%) Query: 36 EEVLLEKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFC 95 E+VL+ +G G++TLNRPK +N+LT M+ + +L WE D +++ GAG + C Sbjct: 9 EDVLVNVEGGVGLLTLNRPKAINSLTHGMVTTMAERLAAWENDDSVRAVLLTGAGERGLC 68 Query: 96 AGGDIRVISEAEKAKQKIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQ 155 AGGD+ I + KA A F+ +EY LN +G KPYV+++ GI MGGGVG+ HG Sbjct: 69 AGGDVVAIYHSAKADGAEARRFWFDEYRLNAHIGRYPKPYVSIMDGIVMGGGVGVGAHGN 128 Query: 156 FRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGKLGYFLALTGFRLKGRDVYRAGIATH 215 RV T+ AMPE IG PDVGG Y L R GKLG ALTG G D G A H Sbjct: 129 VRVVTDTTKMAMPEVGIGFIPDVGGTYLLSRAPGKLGLHAALTGAPFSGADAIVMGFADH 188 Query: 216 FVDSEKLAMLEEDLLALKSPSKENIASVLENYHTESKIDRDKSFILEEHMDKINSCFSAN 275 +V +K+ ++A + + + L + E + L E I+ C++ + Sbjct: 189 YVPHDKIDEFTRAVIA------DGVDAALAAHAQEP-----PASPLAEQRSWIDECYTGD 237 Query: 276 TVEEIIENLQQDGSSFALEQLKVINKMSPTSLKITLRQLMEGSS-KTLQEVLTMEYRLSQ 334 TV +II L+ + A E +I SP +L +TL + + ++L++ L EYR+S Sbjct: 238 TVADIIAALRAHDAPAAGEAADLIATRSPIALSVTLESVRRAAKLQSLEDTLRQEYRVSC 297 Query: 335 ACMRGHDFHEGVRAVLIDKDQSPKWKPADLKEVTEEDLNNHFKSL 379 A ++ HD EG+RA L+DKD++PKW+PA L EVTE D+ +F + Sbjct: 298 ASLKSHDLVEGIRAQLVDKDRNPKWRPATLAEVTEADVEAYFAPV 342 >4J2U-A nrPDB Length = 365 Score = 220 bits (560), Expect = 9e-58, Method: Compositional matrix adjust. Identities = 131/356 (36%), Positives = 188/356 (52%), Gaps = 26/356 (7%) Query: 37 EVLLEKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCA 96 +VL+ K G ITL+RP LNALT M+++I L+ W DPE L++I G +AFCA Sbjct: 25 DVLIRKVRRAGRITLSRPAALNALTCAMVQEIDAALRGWIGDPEVELVVIDAEGPRAFCA 84 Query: 97 GGDIRVI-SEAEKAKQKIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQ 155 GGDI + F+R EY +N+ + + KP V+L+ G TMGGGVGL H + Sbjct: 85 GGDIAELHGRGVAGDHAFGQDFWRVEYRMNDRIAAFPKPIVSLMQGFTMGGGVGLGCHAR 144 Query: 156 FRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGKLGYFLALTGFRLKGRDVYRAGIATH 215 R+ E +MPE AIGL PDVGG + L R G++G +L LTG R+ D AG A Sbjct: 145 HRIVGETSQISMPECAIGLVPDVGGTHLLARAPGRIGVWLGLTGARMGPGDAIFAGFADR 204 Query: 216 FVD----SEKLAMLEEDLLALKSPSKENIASVLENYHTESKIDRDKSFILEEHMDKINSC 271 FV + +A LE LAL ++ E ++ +L++ +D++ Sbjct: 205 FVPEADWPDLIAALEGGDLALP-----------DHAAPEGRLP-----VLQDEIDRLF-- 246 Query: 272 FSANTVEEIIENLQQDGSSFALEQLKVINKMSPTSLKITLRQLME-GSSKTLQEVLTMEY 330 A T+ EI L+ + A E LK + + SP +L TL L G S ++E L +EY Sbjct: 247 --AGTLAEIPARLEATDTPLAAEALKALRRSSPLALAATLEILQRLGPSAGIREALDLEY 304 Query: 331 RLSQACMRGHDFHEGVRAVLIDKDQSPKWKPADLKEVTEEDLNNHFKSLGSSDLKF 386 R + DF EG+RA +IDKD+SP+W+ D + V E++ + LG L F Sbjct: 305 RFTYRAQGQADFLEGIRAAIIDKDRSPRWRHGDPEAVRPEEVASLLAPLGPQALTF 360 >5MRE-88 nrPDB Length = 457 Score = 192 bits (489), Expect = 2e-49, Method: Compositional matrix adjust. Identities = 124/352 (35%), Positives = 188/352 (53%), Gaps = 30/352 (8%) Query: 35 AEEVLLEKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAG-GKA 93 A VL + VITLNRPK LNAL M ++ L ++ + T L+I+K + ++ Sbjct: 1 APPVLFTVQDTARVITLNRPKKLNALNAEMSESMFKTLNEYAKSDTTNLVILKSSNRPRS 60 Query: 94 FCAGGDIRVISEAEKAKQKIAPV-FFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSV 152 FCAGGD+ ++ K+ + FF +EY LN + + KP V + GITMGGGVGLS+ Sbjct: 61 FCAGGDVATVAIFNFNKEFAKSIKFFTDEYSLNFQIATYLKPIVTFMDGITMGGGVGLSI 120 Query: 153 HGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRL------QGKLGYFLALTGFRLKGRD 206 H FR+ATE +AMPE IG FPDVG + LPR+ ++ +L LTG + G D Sbjct: 121 HTPFRIATENTKWAMPEMDIGFFPDVGSTFALPRIVTLANSNSQMALYLCLTGEVVTGAD 180 Query: 207 VYRAGIATHFVDSEKLAMLEEDLLALKSPSKENIASVLENYHTESKIDR-----DKSFIL 261 Y G+A+H+V SE L L++ L + P + S ID K ++ Sbjct: 181 AYMLGLASHYVSSENLDALQKRLGEISPPFNNDPQSAYFFGMVNESIDEFVSPLPKDYVF 240 Query: 262 E---EHMDKINSCFSAN---TVEEIIENLQQ-----DGSSFALE-QLKVINKMSPTSLKI 309 + E ++ I +CF+ + T+E+I+ NL+Q +G +FA E + K++ K SP+SL+I Sbjct: 241 KYSNEKLNVIEACFNLSKNGTIEDIMNNLRQYEGSAEGKAFAQEIKTKLLTK-SPSSLQI 299 Query: 310 TLRQLMEGSSKTLQEVLTME-YRLSQACMRGH---DFHEGVRAVLIDKDQSP 357 LR + E S ++ + + Y + CM +F E + LIDK + P Sbjct: 300 ALRLVQENSRDHIESAIKRDLYTAANMCMNQDSLVEFSEATKHKLIDKQRVP 351 >3JU1-A nrPDB Length = 407 Score = 185 bits (469), Expect = 3e-47, Method: Compositional matrix adjust. Identities = 118/336 (35%), Positives = 184/336 (54%), Gaps = 19/336 (5%) Query: 46 TGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRVISE 105 GV+TLN K LNAL L+M+R + QL W++DP +++ G+G KAFCAGGD+R + Sbjct: 52 VGVVTLNVEKALNALDLDMVRAMTVQLNLWKKDPLIACVVLDGSGEKAFCAGGDVRALYH 111 Query: 106 AEKAKQ----KIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATE 161 A A + ++A VFF EEY L+ + + KP + GI MGGG+GL +V TE Sbjct: 112 ASVAAKGQVTEVAKVFFEEEYRLDYLLHTYGKPVLVWGDGIVMGGGLGLMAGASHKVVTE 171 Query: 162 KCLFAMPETAIGLFPDVGGGYFLPRLQGKLGYFLALTGFRLKGRDVYRAGIATHFVDSEK 221 AMPE IGL+PDVGG YFL R+ GK+G FL LT + + D G+A H+++ + Sbjct: 172 TSRIAMPEVTIGLYPDVGGSYFLNRMPGKMGLFLGLTAYHMNAADACYVGLADHYLNRDD 231 Query: 222 LAMLEEDLLAL---KSPS--KENIASVLENYHTESKIDRDKSFILE--EHMDKINSCFSA 274 ++ + + L SP+ + + +++ + I + S + E E +D++ A Sbjct: 232 KELMFDAMATLDWSDSPALNHQRLDTMINELSNQVDIPKGDSVLAESQEMIDRL----MA 287 Query: 275 NTVEEIIENLQQDGSSFAL--EQLKVINKMSPTSLKITLRQLMEGSSKTLQEVLTMEYRL 332 ++ +I+ + + A + + SP S + Q G+ +L + E + Sbjct: 288 GSLTDIVTRMSTLSTDEAWLSKACATMLAGSPISWHLAYIQTQLGTKLSLAQCFKWELTV 347 Query: 333 S-QACMRGHDFHEGVRAVLIDKDQSPKWKPADLKEV 367 S C +G DF EGVRA+LIDKD+ PKW+ AD++ V Sbjct: 348 SVNVCAKG-DFCEGVRALLIDKDKQPKWQFADVQSV 382 >5ZAI-A nrPDB Length = 259 Score = 104 bits (260), Expect = 6e-23, Method: Compositional matrix adjust. Identities = 70/207 (33%), Positives = 112/207 (54%), Gaps = 14/207 (6%) Query: 36 EEVLLEKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFC 95 E + +K+G ITLNRP LNAL ++ ++ + + E DPE +III G G KAFC Sbjct: 4 ETIETKKEGNLFWITLNRPDKLNALNAKLLEELDRAVSQAESDPEIRVIIITGKG-KAFC 62 Query: 96 AGGDIRVISEAEKAKQKIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQ 155 AG DI ++ A+ A F ++ + + + + KP +A+I+G +GGG+ L++ Sbjct: 63 AGADITQFNQLTPAE---AWKFSKKGREIMDKIEALSKPTIAMINGYALGGGLELALACD 119 Query: 156 FRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGK-LGYFLALTGFRLKGRDVYRAGIAT 214 R+A E+ +PE +G++P GG L R+ GK + +TG R+ G+D + G+ Sbjct: 120 IRIAAEEAQLGLPEINLGIYPGYGGTQRLTRVIGKGRALEMMMTGDRIPGKDAEKYGLVN 179 Query: 215 HFVDSEKLAMLEEDL------LALKSP 235 V LA LE++ +A KSP Sbjct: 180 RVV---PLANLEQETRKLAEKIAKKSP 203 >5Z7R-A nrPDB Length = 267 Score = 100 bits (248), Expect = 1e-21, Method: Compositional matrix adjust. Identities = 70/241 (29%), Positives = 111/241 (46%), Gaps = 13/241 (5%) Query: 38 VLLEKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCAG 97 V+LEK+G V+T+NRPK LNAL + ++++ + + E D E +I+ GAG K+F AG Sbjct: 6 VILEKEGKVAVVTINRPKALNALNSDTLKEMDYVIGEIENDSEVLAVILTGAGEKSFVAG 65 Query: 98 GDIRVISEAEKAKQK----IAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVH 153 DI + E + + + FR +L +KP +A ++G +GGG +++ Sbjct: 66 ADISEMKEMNTIEGRKFGILGNKVFRRLELL-------EKPVIAAVNGFALGGGCEIAMS 118 Query: 154 GQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQG-KLGYFLALTGFRLKGRDVYRAGI 212 R+A+ F PE +G+ P GG L RL G + L T +K + R G+ Sbjct: 119 CDIRIASSNARFGQPEVGLGITPGFGGTQRLSRLVGMGMAKQLIFTAQNIKADEALRIGL 178 Query: 213 ATHFVDSEKLAMLEEDLLALKSPSKENIASVLENYHTESKIDRDKSFILEEHMDKINSCF 272 V+ +L M +A K S +A L + D L + CF Sbjct: 179 VNKVVEPSEL-MNTAKEIANKIVSNAPVAVKLSKQAINRGMQCDIDTALAFESEAFGECF 237 Query: 273 S 273 S Sbjct: 238 S 238 >2HW5-A nrPDB Length = 286 Score = 97.1 bits (240), Expect = 1e-20, Method: Compositional matrix adjust. Identities = 67/196 (34%), Positives = 98/196 (50%), Gaps = 20/196 (10%) Query: 36 EEVLLEKKG---CTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGK 92 E ++ EK+G G+I LNRPK LNAL +I ++ LK +E+DP I++ G G K Sbjct: 30 EYIIAEKRGKNNTVGLIQLNRPKALNALCDGLIDELNQALKIFEEDPAVGAIVLTG-GDK 88 Query: 93 AFCAGGDIRVISEAEKAKQKIAPVFFREEYMLN-----NAVGSCQKPYVALIHGITMGGG 147 AF AG DI+ ++ + F++ Y + + +KP +A ++G GGG Sbjct: 89 AFAAGADIK----------EMQNLSFQDCYSSKFLKHWDHLTQVKKPVIAAVNGYAFGGG 138 Query: 148 VGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGK-LGYFLALTGFRLKGRD 206 L++ A EK FA PE IG P GG L R GK L + LTG R+ +D Sbjct: 139 CELAMMCDIIYAGEKAQFAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQD 198 Query: 207 VYRAGIATHFVDSEKL 222 +AG+ + E L Sbjct: 199 AKQAGLVSKICPVETL 214 >3H81-A nrPDB Length = 278 Score = 97.1 bits (240), Expect = 1e-20, Method: Compositional matrix adjust. Identities = 58/188 (30%), Positives = 94/188 (50%), Gaps = 7/188 (3%) Query: 36 EEVLLEKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFC 95 E +L+E+ G+ITLNRP+ LNAL ++ ++ + + DP+ III G+ KAF Sbjct: 25 ETILVERDQRVGIITLNRPQALNALNSQVMNEVTSAATELDDDPDIGAIIITGSA-KAFA 83 Query: 96 AGGDIRVISEAEKAKQKIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQ 155 AG DI+ E A A F + + + + + P +A + G +GGG L++ Sbjct: 84 AGADIK-----EMADLTFADAFTADFFATWGKLAAVRTPTIAAVAGYALGGGCELAMMCD 138 Query: 156 FRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGKLGYF-LALTGFRLKGRDVYRAGIAT 214 +A + F PE +G+ P +GG L R GK L LTG + + R+G+ + Sbjct: 139 VLIAADTAKFGQPEIKLGVLPGMGGSQRLTRAIGKAKAMDLILTGRTMDAAEAERSGLVS 198 Query: 215 HFVDSEKL 222 V ++ L Sbjct: 199 RVVPADDL 206 >2DUB-A nrPDB Length = 261 Score = 94.4 bits (233), Expect = 8e-20, Method: Compositional matrix adjust. Identities = 64/189 (33%), Positives = 95/189 (50%), Gaps = 10/189 (5%) Query: 38 VLLEKKG---CTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAF 94 ++ EKKG G+I LNRPK LNAL +I ++ L+ +E+DP I++ G G KAF Sbjct: 7 IITEKKGKNSSVGLIQLNRPKALNALCNGLIEELNQALETFEEDPAVGAIVLTG-GEKAF 65 Query: 95 CAGGDIRVISEAEKAKQKIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHG 154 AG DI+ + + Q F + + + +KP +A ++G +GGG L++ Sbjct: 66 AAGADIKEMQN--RTFQDCYSGKFLSHW---DHITRIKKPVIAAVNGYALGGGCELAMMC 120 Query: 155 QFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGK-LGYFLALTGFRLKGRDVYRAGIA 213 A EK F PE +G P GG L R GK L + LTG R+ +D +AG+ Sbjct: 121 DIIYAGEKAQFGQPEILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLV 180 Query: 214 THFVDSEKL 222 + E L Sbjct: 181 SKIFPVETL 189 >4ZU2-A nrPDB Length = 272 Score = 87.4 bits (215), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 64/201 (31%), Positives = 99/201 (49%), Gaps = 5/201 (2%) Query: 36 EEVLLEKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFC 95 E +LLE ITLNRP+ NA++L M+ ++ L D ++++GA G FC Sbjct: 7 ETLLLEPIEGVLRITLNRPQSRNAMSLAMVGELRAVLAAVRDDRSVRALVLRGADGH-FC 65 Query: 96 AGGDIRVISEAEKAKQKIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQ 155 AGGDI+ ++ A A + R L + + VAL+ G +GGG GL+ Sbjct: 66 AGGDIKDMAGARAAGAEAYRTLNRAFGSLLEEAQAAPQLLVALVEGAVLGGGFGLACVSD 125 Query: 156 FRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGKLGYFLALTGFRLKGRDVYRAGIATH 215 +A F +PET++G+ P + + R+ LALT R GR+ R G+ H Sbjct: 126 VAIAAADAQFGLPETSLGILPAQIAPFVVRRIGLTQARRLALTAARFDGREALRLGL-VH 184 Query: 216 FVDSEKLAM---LEEDLLALK 233 F +++ A+ LEE L L+ Sbjct: 185 FCEADADALEQRLEETLEQLR 205 >5WYB-B nrPDB Length = 280 Score = 83.2 bits (204), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 58/203 (28%), Positives = 98/203 (48%), Gaps = 10/203 (4%) Query: 20 NTILHHLRMSKHTDAAEEVLLEKKGCTGVITLNRP--KFLNALTLNMIRQIYPQLKKWEQ 77 NT + + S D ++ +EK G T +IT+N P + +L +RQ+ L + Sbjct: 2 NTAVEPYKASSFDDT-HKLTVEKHGHTALITINHPPANTWDRDSLIGLRQLIEHLNR--- 57 Query: 78 DPETFLIIIKGAGGKAFCAGGDIRVISEAEKAKQKIAPVFFREEYMLNNAVGSCQKPYVA 137 D + + +++ G G K F AG D+ + ++ +KA+ + F E + A+ + +A Sbjct: 58 DDDIYALVVTGQGPKFFSAGADLNMFADGDKARAREMARRFGEAF---EALRDFRGVSIA 114 Query: 138 LIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGK-LGYFLA 196 I+G MGGG+ ++ R+A + A+PE A+GL P GG LP L G+ + Sbjct: 115 AINGYAMGGGLECALACDIRIAERQAQMALPEAAVGLLPCAGGTQALPWLVGEGWAKRMI 174 Query: 197 LTGFRLKGRDVYRAGIATHFVDS 219 L R+ R G+ VDS Sbjct: 175 LCNERVDAETALRIGLVEQVVDS 197 >5YLO-A nrPDB Length = 271 Score = 80.1 bits (196), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 72/310 (23%), Positives = 124/310 (40%), Gaps = 68/310 (21%) Query: 49 ITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRVISEAEK 108 + LNRP+ NAL + + ++ +L E+DP +++ G+G ++FCAG D+ + AE Sbjct: 18 LVLNRPQQRNALDIPTLEALHVRLDACERDPAVRAVVLGGSG-RSFCAGADLAEWAAAEA 76 Query: 109 AKQKIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMP 168 + + + + L + + KP VA ++G +G G+ L++ FR+A F Sbjct: 77 RGELESYGWTEAAHALMGRLHALDKPTVAAVNGSAVGAGMDLALCCDFRIAAASARFKAG 136 Query: 169 ETAIGLFPDVGGGYFLPRLQGKLGYFLALTGFRLKGRDVYRAGIATHFVDSEKLAMLEED 228 T + PD G + LPRL G +++L L+E Sbjct: 137 YTGMAYCPDAGASWHLPRLLGSEA--------------------------AKRLLFLDEA 170 Query: 229 LLALKSPSKENIASVLENYHTESKIDRDKSFILEEHMDKINSCFSANTVEEIIENLQQDG 288 A ++ + V + +EH+ + F+A G Sbjct: 171 WSAERALGAGLVGEV----------------VADEHLVEAVGAFAARLA---------SG 205 Query: 289 SSFALEQLKVINKMSPTSLKITLRQLMEGSSKTLQEVLTMEYRLSQACMRGHDFHEGVRA 348 +FA Q K R L +G+ ++L E L E C R D E +RA Sbjct: 206 PTFAFAQTK--------------RLLRDGAGRSLAEQLRAEQAAGLLCGRSEDAAEALRA 251 Query: 349 VLIDKDQSPK 358 V + +SP+ Sbjct: 252 VA--EKRSPQ 259 >3MOY-A nrPDB Length = 263 Score = 77.8 bits (190), Expect = 7e-15, Method: Compositional matrix adjust. Identities = 55/179 (30%), Positives = 87/179 (48%), Gaps = 11/179 (6%) Query: 47 GVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRVISEA 106 G+I L+RP LNAL + ++ + ++ D E I++ G+ +AF AG DI A Sbjct: 21 GLIRLDRPDALNALNQTLEAEVLDAARDFDADLEIGAIVVTGSE-RAFAAGADI-----A 74 Query: 107 EKAKQKIAPVFFREEYMLN--NAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCL 164 E + P RE +L+ +++ +KP VA + G +GGG L++ +A + Sbjct: 75 EMVT--LTPHQARERNLLSGWDSLTQVRKPIVAAVAGYALGGGCELAMLCDLVIAADTAR 132 Query: 165 FAMPETAIGLFPDVGGGYFLPRLQGKLGYF-LALTGFRLKGRDVYRAGIATHFVDSEKL 222 F PE +G+ P +GG L R GK L LTG L + R G+ + V + L Sbjct: 133 FGQPEITLGILPGLGGTQRLTRAVGKAKAMDLCLTGRSLTAEEAERVGLVSRIVPAADL 191 >4JWV-A nrPDB Length = 278 Score = 77.0 bits (188), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 60/200 (30%), Positives = 93/200 (46%), Gaps = 17/200 (8%) Query: 49 ITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRVISEAEK 108 + LNRP+ LNA+T M + + + + + +++ G KAFC G D+ S + Sbjct: 37 VRLNRPQGLNAITQEMDDLLLDAWTEVNANSDIWAVVLSAEGEKAFCIGADV---SGGAE 93 Query: 109 AKQKIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMP 168 K ++A +C+KP VA + G +GGG L++ VA + F +P Sbjct: 94 RKTRMALGGGLTGIGGPLV--TCKKPMVAAVQGFCVGGGFELAMCADIIVAADTAQFGLP 151 Query: 169 ETAIGLFPDVGGGYFLPRLQGKLGYFLA----LTGFRLKGRDVYRAGIATHFVDSEKLAM 224 ET +G+ + G + R +L Y +A LTG R+K + G+ V A Sbjct: 152 ETKVGIIGECG---VVHRAMRQLPYHIALQLILTGERIKADEARHYGLVNEVV---PFAE 205 Query: 225 LEEDLLALKSPSKENIASVL 244 LEE AL+ SK N AS L Sbjct: 206 LEE--AALRWASKLNAASPL 223 >6IUM-B nrPDB Length = 701 Score = 70.9 bits (172), Expect = 8e-13, Method: Compositional matrix adjust. Identities = 51/142 (35%), Positives = 72/142 (50%), Gaps = 9/142 (6%) Query: 48 VITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRVISEAE 107 VITL+ P +N L + I + + D I+I GAG KAF G DIR + Sbjct: 13 VITLDNPP-VNGLGHSTRLGIVEGMTRALDDAAVKAIVITGAG-KAFSGGADIREFN-TP 69 Query: 108 KAKQKIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAM 167 KA Q+ P +L + KP VA +H + MGGG+ L++ +RVA++ A+ Sbjct: 70 KAMQE--PTLHSVIRVLEGS----SKPVVAAVHSVAMGGGLELALGCNYRVASKGAQIAL 123 Query: 168 PETAIGLFPDVGGGYFLPRLQG 189 PE +GL P GG LPR+ G Sbjct: 124 PEVKLGLLPGAGGTQRLPRVIG 145 >4FZW-A nrPDB Length = 258 Score = 70.9 bits (172), Expect = 9e-13, Method: Compositional matrix adjust. Identities = 49/185 (26%), Positives = 87/185 (47%), Gaps = 7/185 (3%) Query: 37 EVLLEKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCA 96 E+++ ++ ++TLNRP NAL ++ Q+ +L+ D + +I G + F A Sbjct: 6 ELIVSRQQRVLLLTLNRPAARNALNNALLMQLVNELEAAATDTSISVCVITG-NARFFAA 64 Query: 97 GGDIRVISEAEKAKQKIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQF 156 G D+ E A++ +A L + + KP +A ++G +G G L++ Sbjct: 65 GADLN-----EMAEKDLAATLNDTRPQLWARLQAFNKPLIAAVNGYALGAGCELALLCDV 119 Query: 157 RVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGK-LGYFLALTGFRLKGRDVYRAGIATH 215 VA E F +PE +G+ P GG L R GK L + L+G + + +AG+ + Sbjct: 120 VVAGENARFGLPEITLGIMPGAGGTQRLIRSVGKSLASKMVLSGESITAQQAQQAGLVSD 179 Query: 216 FVDSE 220 S+ Sbjct: 180 VFPSD 184 Score = 27.7 bits (60), Expect = 9.7, Method: Compositional matrix adjust. Identities = 19/70 (27%), Positives = 33/70 (47%), Gaps = 2/70 (2%) Query: 291 FALEQLKVINKMSPTSLKITLRQLMEGSSKTLQEVLTMEYRLSQACMRGHDFHEGVRAVL 350 +AL+ + + SP +L+ + L + LQ L E +L D HEG+ A L Sbjct: 189 YALQLASKMARHSPLALQAAKQALRQSQEVALQAGLAQERQLFTLLAATEDRHEGISAFL 248 Query: 351 IDKDQSPKWK 360 + ++P +K Sbjct: 249 --QKRTPDFK 256 >5VE2-A nrPDB Length = 275 Score = 70.1 bits (170), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 54/207 (26%), Positives = 93/207 (44%), Gaps = 19/207 (9%) Query: 49 ITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCAGGDIR-VISEAE 107 +T+NRP+ NAL + + +L++ D + +++ A G F AG D+ I+ E Sbjct: 38 LTINRPELKNALNRELYAALADELERSNHDDQIRAVLLT-ANGDTFTAGNDLDDFINPVE 96 Query: 108 KAKQKIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAM 167 ++ F + A+ C+ P V ++G +G G+ + +H A++ F Sbjct: 97 ESGTPSVIRFLK-------AISECETPIVVAVNGPAIGVGLTMLLHCDMVYASKSARFRA 149 Query: 168 PETAIGLFPDVGGGYFLPRLQGKL-GYFLALTGFRLKGRDVYRAGIATHFVDSEKLAMLE 226 P T +GL P+ LP G+ L L G L R+ AG+ T + E Sbjct: 150 PFTHVGLVPEAASSLLLPLAVGQAWANDLMLAGRILDAREALSAGLVTR--------VFE 201 Query: 227 EDLLALKSPS-KENIASVLENYHTESK 252 +D+L +S E +AS+ N +SK Sbjct: 202 DDVLVAESLKIAEQVASLAPNSVKQSK 228 >3T88-A nrPDB Length = 289 Score = 69.7 bits (169), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 41/142 (28%), Positives = 68/142 (47%), Gaps = 1/142 (0%) Query: 49 ITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRVISEAEK 108 IT+NRP+ NA ++++ L D +II+ GAG KAFC+GGD +V + Sbjct: 41 ITINRPQVRNAFRPLTVKEMIQALADARYDDNIGVIILTGAGDKAFCSGGDQKVRGDYGG 100 Query: 109 AKQKIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMP 168 K + V + +C KP VA++ G ++GGG L + +A + +F Sbjct: 101 YKDD-SGVHHLNVLDFQRQIRTCPKPVVAMVAGYSIGGGHVLHMMCDLTIAADNAIFGQT 159 Query: 169 ETAIGLFPDVGGGYFLPRLQGK 190 +G F G ++ R+ G+ Sbjct: 160 GPKVGSFDGGWGASYMARIVGQ 181 >2IEX-A nrPDB Length = 272 Score = 69.3 bits (168), Expect = 3e-12, Method: Compositional matrix adjust. Identities = 44/154 (28%), Positives = 69/154 (44%), Gaps = 2/154 (1%) Query: 36 EEVLLEKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFC 95 E+++ E IT+NRP+ NA + ++ K D +II+ GAGGKAFC Sbjct: 12 EDIIYETYNGIAKITINRPEVHNAFRPKTVNEMIDAFTKARDDSNIGVIILTGAGGKAFC 71 Query: 96 AGGDIRVISEAEKAKQKIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQ 155 +GGD +V + P + L + KP +A++ G +GGG L V Sbjct: 72 SGGDQKVRGHGGYVGEDEIPRLNVLD--LQRLIRVIPKPVIAMVAGYAIGGGHVLHVVCD 129 Query: 156 FRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQG 189 +A + +F +G F G +L R+ G Sbjct: 130 LTIAADNAIFGQTGPKVGSFDGGYGAGYLARIVG 163 >5KJP-A nrPDB Length = 265 Score = 65.5 bits (158), Expect = 4e-11, Method: Compositional matrix adjust. Identities = 57/189 (30%), Positives = 87/189 (46%), Gaps = 13/189 (6%) Query: 28 MSKHTDAAE---EVLLEKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLI 84 MS +DAA EVL+E++ +IT+NRPK NA+ + R + + + + D + Sbjct: 4 MSSESDAANTEPEVLVEQRDRILIITINRPKAKNAVNAAVSRGLADAMDQLDGDAGLSVA 63 Query: 85 IIKGAGGKAFCAGGDIRVISEAEKAKQKIAPVFFREEYMLNNAVGSCQKPYVALIHGITM 144 I+ G GG +FCAG D++ + E + + F E KP +A + G + Sbjct: 64 ILTGGGG-SFCAGMDLKAFARGENVVVEGRGLGFTER--------PPTKPLIAAVEGYAL 114 Query: 145 GGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLP-RLQGKLGYFLALTGFRLK 203 GG L++ VA F +PE GL GG LP R+ + LALTG L Sbjct: 115 AGGTELALAADLIVAARDSAFGIPEVKRGLVAGGGGLLRLPERIPYAIAMELALTGDNLP 174 Query: 204 GRDVYRAGI 212 + G+ Sbjct: 175 AERAHELGL 183 >4FZW-C nrPDB Length = 274 Score = 64.7 bits (156), Expect = 7e-11, Method: Compositional matrix adjust. Identities = 56/179 (31%), Positives = 85/179 (47%), Gaps = 5/179 (2%) Query: 48 VITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCAGGDI--RVISE 105 +TLNRP+ LN+ M Q+ LK+ E+D +++ GAG + FCAG D+ R + Sbjct: 27 TLTLNRPERLNSFNDEMHAQLAECLKQVERDDTIRCLLLTGAG-RGFCAGQDLNDRNVDP 85 Query: 106 AEKAKQKIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLF 165 A + R L + KP + ++G+ G G L++ G +A F Sbjct: 86 TGPAPD-LGMSVERFYNPLVRRLAKLPKPVICAVNGVAAGAGATLALGGDIVIAARSAKF 144 Query: 166 AMPETAIGLFPDVGGGYFLPRLQGKL-GYFLALTGFRLKGRDVYRAGIATHFVDSEKLA 223 M + +GL PD GG + LPR+ G+ LAL G +L + G+ VD E LA Sbjct: 145 VMAFSKLGLIPDCGGTWLLPRVAGRARAMGLALLGNQLSAEQAHEWGMIWQVVDDETLA 203 >5JBW-A nrPDB Length = 260 Score = 63.2 bits (152), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 46/182 (25%), Positives = 82/182 (45%), Gaps = 4/182 (2%) Query: 37 EVLLEKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCA 96 E ++ +G + T++ NA++ M++++ + + + ++I GAG KAFCA Sbjct: 5 EFKVDARGPIEIWTIDGESRRNAISRAMLKELGELVTRVSSSRDVRAVVITGAGDKAFCA 64 Query: 97 GGDIRVISEAEKAKQKIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQF 156 G D++ A A+ ++ F A+ ++A I+G +GGG L++ Sbjct: 65 GADLK--ERATMAEDEV-RAFLDGLRRTFRAIEKSDCVFIAAINGAALGGGTELALACDL 121 Query: 157 RVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGK-LGYFLALTGFRLKGRDVYRAGIATH 215 RVA + E +G+ P GG L RL G L LT R+ + + G+A Sbjct: 122 RVAAPAAELGLTEVKLGIIPGGGGTQRLARLVGPGRAKDLILTARRINAAEAFSVGLANR 181 Query: 216 FV 217 Sbjct: 182 LA 183 >5ZRV-A nrPDB Length = 763 Score = 62.0 bits (149), Expect = 4e-10, Method: Compositional matrix adjust. Identities = 54/221 (24%), Positives = 100/221 (45%), Gaps = 17/221 (7%) Query: 9 LMSRFNAFKRTNT---ILHHLRMSKHTDAAEEVLLEKKGCTGVITLNRPKFLNALTLNMI 65 ++SRF+AF+ + I + S + KG V+ +N P N+ + Sbjct: 9 ILSRFSAFRILRSRGYICRNFTGSSALLTRTHINYGVKGDVAVVRINSP---NSKVNTLS 65 Query: 66 RQIYPQLKK-----WEQDPETFLIIIKGAGGKAFCAGGDIRVISEAEKAKQKIAPVFFRE 120 ++++ + + W D ++I G F AG DI +++ A K Q++ +E Sbjct: 66 KELHSEFSEVMNEIWASDQIRSAVLISSKPG-CFIAGADINMLA-ACKTLQEVTQ-LSQE 122 Query: 121 EYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATE--KCLFAMPETAIGLFPDV 178 + + KP VA I+G +GGG+ +++ Q+R+AT+ K + PE +G P Sbjct: 123 AQRIVEKLEKSTKPIVAAINGSCLGGGLEVAISCQYRIATKDRKTVLGTPEVLLGALPGA 182 Query: 179 GGGYFLPRLQGKLGYF-LALTGFRLKGRDVYRAGIATHFVD 218 GG LP++ G + LTG ++ + G+ V+ Sbjct: 183 GGTQRLPKMVGVPAALDMMLTGRSIRADRAKKMGLVDQLVE 223 >4JFC-A nrPDB Length = 281 Score = 60.5 bits (145), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 54/176 (30%), Positives = 88/176 (50%), Gaps = 10/176 (5%) Query: 42 KKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCAGGDIR 101 +G T ++TL+ P+F NAL + L E +PE ++I G G FCAGG+++ Sbjct: 31 SEGQTLILTLSNPEFRNALGPEIYAAGIEALNAAENNPEIRSVVITGEG-AVFCAGGNLQ 89 Query: 102 VISEAEKAKQKIAP-VFFREEYMLNNAVGSCQ---KPYVALIHGITMGGGVGLSVHGQFR 157 + +A ++ AP V + L+N + S + KP +A + G G G L++ F Sbjct: 90 RL----QANRREAPEVQAQSIEGLHNWIDSIRTYPKPVIAAVEGAAAGAGFSLALACDFV 145 Query: 158 VATEKCLFAMPETAIGLFPDVGGGYFLPR-LQGKLGYFLALTGFRLKGRDVYRAGI 212 VA +F M + +GL PD GG + L R L L L + G R+ + ++ G+ Sbjct: 146 VAASNAVFVMSYSTVGLSPDGGGSWSLARSLPRALASELLMGGERISAQRLHDLGL 201 >4IZC-A nrPDB Length = 275 Score = 60.5 bits (145), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 57/214 (26%), Positives = 95/214 (44%), Gaps = 13/214 (6%) Query: 48 VITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRVISEAE 107 V+TLNRP NAL + I ++ + +++ GAG FCAG D+ +A+ Sbjct: 23 VVTLNRPDKRNALDVATIEELVTFFSTAHR-KGVRAVVLTGAGDH-FCAGLDLVEHWKAD 80 Query: 108 KAKQKIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAM 167 ++ V R N + P +A + G +GGG+ L+ RV + FA+ Sbjct: 81 RSADDFMHVCLRWHEAFNK-MEYGGVPIIAALRGAVVGGGLALASAAHLRVMDQSTYFAL 139 Query: 168 PETAIGLFPDVGGGYFLPRLQGKLGYF----LALTGFRLKGRDVYRAGIATHFVDSEKL- 222 PE G+F GGG + R+ +G + + LTG +G++ G+A + + Sbjct: 140 PEGQRGIF--TGGGATI-RVSDMIGKYRMIDMILTGRVYQGQEAADLGLAQYITEGSSFD 196 Query: 223 -AMLEEDLLALKSP-SKENIASVLENYHTESKID 254 AM D +A P + I S + + S +D Sbjct: 197 KAMELADKIASNLPLTNFAICSAISHMQNMSGLD 230 >4JCS-A nrPDB Length = 286 Score = 60.1 bits (144), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 45/187 (24%), Positives = 80/187 (42%), Gaps = 20/187 (10%) Query: 46 TGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRVISE 105 G I +NR N + + L++ D + ++++ G +FCAGG++ V+ + Sbjct: 34 VGWIRMNRAAKHNPFDAELRADLMTVLERVRDDADIRVLVLTSHPG-SFCAGGNLHVLRD 92 Query: 106 AEKAKQKIAPVFFREEY---------MLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQF 156 P ++++ MLN +P +A + G G G LS+ Sbjct: 93 ----NLDSGPAYWQQRIKTGLRFIHDMLN-----LGRPVIAAVDGPAFGAGFALSLTADI 143 Query: 157 RVATEKCLFAMPETAIGLFPDVGGGYFLPRLQG-KLGYFLALTGFRLKGRDVYRAGIATH 215 +A+ + F+M +GL PD+G Y LPR G + L + L + +R G+ Sbjct: 144 VLASPRARFSMAYLRLGLVPDLGALYLLPRAVGLQRAKELMFSTRELDAEEAHRLGLVME 203 Query: 216 FVDSEKL 222 +SE L Sbjct: 204 VHESEAL 210 >3HIN-A nrPDB Length = 275 Score = 59.7 bits (143), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 47/158 (29%), Positives = 72/158 (45%), Gaps = 18/158 (11%) Query: 38 VLLEKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQD-PETFLIIIKGAGGKAFCA 96 ++++ G I LNRPK NAL ++ LK D P+ ++ G F A Sbjct: 18 LVVDTVGPVLTIGLNRPKKRNALNDGLM----AALKDCLTDIPDQIRAVVIHGIGDHFSA 73 Query: 97 GGDIRVISEAEKAK-----QKIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLS 151 G D+ + E + + Q VF + +Y C+ P +A + G +GGG+ L+ Sbjct: 74 GLDLSELRERDATEGLVHSQTWHRVFDKIQY--------CRVPVIAALKGAVIGGGLELA 125 Query: 152 VHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQG 189 RVA +A+PE + G+F GG LPRL G Sbjct: 126 CAAHIRVAEASAYYALPEGSRGIFVGGGGSVRLPRLIG 163 >1NZY-B nrPDB Length = 269 Score = 59.3 bits (142), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 39/146 (26%), Positives = 73/146 (50%), Gaps = 9/146 (6%) Query: 49 ITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRVIS---- 104 IT+ P+ NAL++ ++++ L + E+D ++I GA AFCAG +R I Sbjct: 16 ITIKLPRHRNALSVKAMQEVTDALNRAEEDDSVGAVMITGAE-DAFCAGFYLREIPLDKG 74 Query: 105 -EAEKAKQKIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKC 163 + +IA +++ + M++ + ++P +A I+G+ GGG+G+S+ + + Sbjct: 75 VAGVRDHFRIAALWWHQ--MIHKII-RVKRPVLAAINGVAAGGGLGISLASDMAICADSA 131 Query: 164 LFAMPETAIGLFPDVGGGYFLPRLQG 189 F IG+ D Y L R+ G Sbjct: 132 KFVCAWHTIGIGNDTATSYSLARIVG 157 >2UZF-A nrPDB Length = 273 Score = 58.9 bits (141), Expect = 4e-09, Method: Compositional matrix adjust. Identities = 36/141 (25%), Positives = 62/141 (43%), Gaps = 2/141 (1%) Query: 49 ITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRVISEAEK 108 +T+NRP+ NA T + ++ + D +I++ G G AFC+GGD + Sbjct: 26 VTINRPEVRNAFTPKTVAEMIDAFSRARDDQNVSVIVLTGEGDLAFCSGGDQKKRGHGGY 85 Query: 109 AKQKIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMP 168 + P + L + KP +A++ G +GGG L+V +A + +F Sbjct: 86 VGEDQIPRLNVLD--LQRLIRIIPKPVIAMVKGYAVGGGNVLNVVCDLTIAADNAIFGQT 143 Query: 169 ETAIGLFPDVGGGYFLPRLQG 189 +G F G +L R+ G Sbjct: 144 GPKVGSFDAGYGSGYLARIVG 164 >3ZWA-A nrPDB Length = 742 Score = 58.5 bits (140), Expect = 4e-09, Method: Compositional matrix adjust. Identities = 55/179 (30%), Positives = 82/179 (45%), Gaps = 18/179 (10%) Query: 48 VITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRVISEAE 107 +I L P +NA++ +IR++ L+K D I+I GA G FCAG DI S Sbjct: 33 MIRLCNPP-VNAVSPTVIREVRNGLQKAGSDHTVKAIVICGANGN-FCAGADIHGFSA-- 88 Query: 108 KAKQKIAPVFFREEYMLNNAVGSCQ---KPYVALIHGITMGGGVGLSVHGQFRVATEKCL 164 F L + V Q KP +A I G+ +GGG+ L++ +R+A K Sbjct: 89 ----------FTPGLALGSLVDEIQRYQKPVLAAIQGVALGGGLELALGCHYRIANAKAR 138 Query: 165 FAMPETAIGLFPDVGGGYFLPRLQG-KLGYFLALTGFRLKGRDVYRAGIATHFVDSEKL 222 +PE +G+ P G LPR+ G + L +G L + R GI V S+ + Sbjct: 139 VGLPEVTLGILPGARGTQLLPRVVGVPVALDLITSGKYLSADEALRLGILDAVVKSDPV 197 >4EML-A nrPDB Length = 275 Score = 57.8 bits (138), Expect = 9e-09, Method: Compositional matrix adjust. Identities = 46/168 (27%), Positives = 74/168 (44%), Gaps = 10/168 (5%) Query: 28 MSKHTDAAEEVLLEKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIK 87 ++KH D ++L K G I +NRP NA + ++Y +D ++++ Sbjct: 5 IAKHYD---DILYYKAGGIAKIVINRPHKRNAFRPQTVFELYDAFCNAREDNRIGVVLLT 61 Query: 88 GAG----GK-AFCAGGDIRVISEAEKAKQKIAPVFFREEYMLNNAVGSCQKPYVALIHGI 142 GAG GK AFC+GGD V E + P + L + S K +AL+ G Sbjct: 62 GAGPHSDGKYAFCSGGDQSVRGEGGYIDDQGTPRLNVLD--LQRLIRSMPKVVIALVAGY 119 Query: 143 TMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGK 190 +GGG L + +A + +F +G F G +L R+ G+ Sbjct: 120 AIGGGHVLHLVCDLTIAADNAIFGQTGPKVGSFDGGFGSSYLARIVGQ 167 >2D3T-A nrPDB Length = 715 Score = 57.4 bits (137), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 41/133 (30%), Positives = 58/133 (43%), Gaps = 4/133 (3%) Query: 57 LNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRVISEAEKAKQKIAPV 116 N LTLN +RQ +K D +I+ +G F G DI E K Sbjct: 32 FNRLTLNELRQAVDAIK---ADASVKGVIVS-SGKDVFIVGADITEFVENFKLPDAELIA 87 Query: 117 FFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFP 176 E + + P VA I+GI +GGG+ + + FRV + +PE +G++P Sbjct: 88 GNLEANKIFSDFEDLNVPTVAAINGIALGGGLEMCLAADFRVMADSAKIGLPEVKLGIYP 147 Query: 177 DVGGGYFLPRLQG 189 GG LPRL G Sbjct: 148 GFGGTVRLPRLIG 160 >2VSU-C nrPDB Length = 275 Score = 54.3 bits (129), Expect = 8e-08, Method: Compositional matrix adjust. Identities = 40/154 (25%), Positives = 75/154 (48%), Gaps = 9/154 (5%) Query: 28 MSKHTDAAEEVLLEKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIK 87 MS + + V +E + + LNRP+ NA++ + R++ L+ EQDP ++++ Sbjct: 1 MSTYEGRWKTVKVEIEDGIAFVILNRPEKRNAMSPTLNREMIDVLETLEQDPAAGVLVLT 60 Query: 88 GAGGKAFCAGGDIR-----VISEAEKAKQKIAPVFFREEYMLNNAVGSCQKPYVALIHGI 142 GA G+A+ AG D++ V + E ++KI + ++ L KP +A+++G Sbjct: 61 GA-GEAWTAGMDLKEYFREVDAGPEILQEKIRREASQWQWKLLRMYA---KPTIAMVNGW 116 Query: 143 TMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFP 176 GGG V + ++ F + E G+ P Sbjct: 117 CFGGGFAPLVACDLAICADEATFGLSEINWGIPP 150 >3HE2-A nrPDB Length = 264 Score = 48.5 bits (114), Expect = 4e-06, Method: Compositional matrix adjust. Identities = 38/146 (26%), Positives = 64/146 (43%), Gaps = 13/146 (8%) Query: 48 VITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRVISEAE 107 I L RP+ NAL ++ ++ ++K D I++ G G AFCAG D+ + A Sbjct: 33 TIELQRPERRNALNSQLVEELTQAIRK-AGDGSARAIVLTGQG-TAFCAGADLSGDAFAA 90 Query: 108 KAKQKIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAM 167 ++ L+ A+ + P V I+G +G G+ L++ RV F Sbjct: 91 DYPDRL--------IELHKAMDASPMPVVGAINGPAIGAGLQLAMQCDLRVVAPDAFFQF 142 Query: 168 PETAIGLFPDVGGGYFLPRLQGKLGY 193 P + GL D + + RL +G+ Sbjct: 143 PTSKYGLALD---NWSIRRLSSLVGH 165 >2A81-A nrPDB Length = 250 Score = 48.5 bits (114), Expect = 4e-06, Method: Compositional matrix adjust. Identities = 35/137 (25%), Positives = 59/137 (43%), Gaps = 8/137 (5%) Query: 48 VITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCAGGD---IRVIS 104 VITL+ P N + + + L + D +++ G ++F AGGD ++ +S Sbjct: 12 VITLDHPNKHNPFSRTLETSVKDALARANADDSVRAVVVYGGAERSFSAGGDFNEVKQLS 71 Query: 105 EAEKAKQKIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCL 164 +E ++ I V L AV + KP +A + G +G G ++ R+ Sbjct: 72 RSEDIEEWIDRVI-----DLYQAVLNVNKPTIAAVDGYAIGMGFQFALMFDQRLMASTAN 126 Query: 165 FAMPETAIGLFPDVGGG 181 F MPE G+ VG Sbjct: 127 FVMPELKHGIGCSVGAA 143 >6OJM-A nrPDB Length = 286 Score = 47.4 bits (111), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 42/162 (25%), Positives = 68/162 (41%), Gaps = 21/162 (12%) Query: 43 KGCTGV--ITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGA------GGKAF 94 K C GV I NRP+ NA ++Y +DP ++++ G GG AF Sbjct: 24 KKCNGVARIAFNRPEIRNAFRPKTTSELYDAFYDAYEDPSIGVVLLSGEGPSPKDGGWAF 83 Query: 95 CAGGDIRVISEAEKAKQKIAPVFFREEYMLN-----NAVGSCQKPYVALIHGITMGGGVG 149 C+GGD +KA+ V + LN + K +A++ G +GGG Sbjct: 84 CSGGD-------QKARGHQGYVGEDGRHRLNILEVQRLIRFMPKVVIAVVPGWAVGGGHS 136 Query: 150 LSVHGQFRVAT-EKCLFAMPETAIGLFPDVGGGYFLPRLQGK 190 L V +A+ E +F + + F G +L ++ G+ Sbjct: 137 LHVVCDLTLASKEHAIFKQTDADVTSFDGGYGSAYLAKMVGQ 178 >2PPY-A nrPDB Length = 265 Score = 47.0 bits (110), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 36/141 (25%), Positives = 64/141 (45%), Gaps = 7/141 (4%) Query: 58 NALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRVISEAEKAKQKIAPVF 117 N+ L ++ + DP+ ++I+ K F AG DI + A+ + K Sbjct: 30 NSYDLEFYKEFNAAIDDIRFDPDIKVVIVMSDVPKFFSAGADINFLRSAD-PRFKTQFCL 88 Query: 118 FREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFR-VATEKCLFAMPETAIGLFP 176 F E + + + + Y+A + G T+GGG+ +++ R + E +PE ++G+ Sbjct: 89 FCNETL--DKIARSPQVYIACLEGHTVGGGLEMALACDLRFMGDEAGKIGLPEVSLGVLA 146 Query: 177 DVGGGYFLPRLQGKLGYFLAL 197 GG L RL +GY AL Sbjct: 147 GTGGTQRLARL---IGYSRAL 164 >3OME-A nrPDB Length = 282 Score = 45.8 bits (107), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 50/187 (26%), Positives = 81/187 (43%), Gaps = 22/187 (11%) Query: 47 GVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRVISEA 106 ITLNRP+ NA ++ ++ + +D E +II++ A GK F AG D+R E Sbjct: 34 ATITLNRPEAANAQNPELLDELDAAWTRAAEDNEVKVIILR-ANGKHFSAGHDLRGGGE- 91 Query: 107 EKAKQKIAPVFFRE-------EYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVA 159 +KI+ F + +Y L + KP +A + G + GG+ L +A Sbjct: 92 --VPEKISLEFIIQHEARRYLDYTLR--WRNVPKPSIAAVQGRCISGGLLLCWPCDLILA 147 Query: 160 TEKCLFAMPETAIGLFPDVGGGYFLPRLQGKLGYFLA----LTGFRLKGRDVYRAGIATH 215 ++ LF+ P +G+ GG +LG A TG L + R G+ Sbjct: 148 SDDALFSDPVALMGI-----GGVEYHGHTWELGPRKAKEILFTGRALTAEEAERTGMVNR 202 Query: 216 FVDSEKL 222 V ++L Sbjct: 203 VVARDEL 209 >2WTB-A nrPDB Length = 725 Score = 45.8 bits (107), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 41/144 (28%), Positives = 71/144 (49%), Gaps = 2/144 (1%) Query: 46 TGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRVISE 105 VITL P +N+L+ +++ + ++ + I+I GA G+ F G DI E Sbjct: 18 VAVITLINPP-VNSLSFDVLYNLKSNYEEALSRNDVKAIVITGAKGR-FSGGFDISGFGE 75 Query: 106 AEKAKQKIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLF 165 +K K + ++ + + + +KP VA I G+ +GGG+ L++ R++ Sbjct: 76 MQKGNVKEPKAGYISIDIITDLLEAARKPSVAAIDGLALGGGLELAMACHARISAPAAQL 135 Query: 166 AMPETAIGLFPDVGGGYFLPRLQG 189 +PE +G+ P GG LPRL G Sbjct: 136 GLPELQLGVIPGFGGTQRLPRLVG 159 >3T8B-A nrPDB Length = 334 Score = 44.3 bits (103), Expect = 8e-05, Method: Compositional matrix adjust. Identities = 47/199 (23%), Positives = 78/199 (39%), Gaps = 32/199 (16%) Query: 7 WRLMSRFNAFKRTNTILHHLRMSKHTDAAEEVLLEKKGCTGVITLNRPKFLNALTLNMIR 66 WRL+ + F I +H +H D A T + NRP+ NA + + Sbjct: 45 WRLV---DGFDDLTDITYH----RHVDDA----------TVRVAFNRPEVRNAFRPHTVD 87 Query: 67 QIYPQLKKWEQDPETFLIIIKGA------GGKAFCAGGDIRV-------ISEAEKAKQKI 113 ++Y L P+ ++++ G GG AFC+GGD R+ + + A Sbjct: 88 ELYRVLDHARMSPDVGVVLLTGNGPSPKDGGWAFCSGGDQRIRGRSGYQYASGDTADTVD 147 Query: 114 APVFFREEYM-LNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVAT-EKCLFAMPETA 171 R + + + K + L++G GGG L V +A+ E F + Sbjct: 148 VARAGRLHILEVQRLIRFMPKVVICLVNGWAAGGGHSLHVVCDLTLASREYARFKQTDAD 207 Query: 172 IGLFPDVGGGYFLPRLQGK 190 +G F G +L R G+ Sbjct: 208 VGSFDGGYGSAYLARQVGQ 226 >3I47-A nrPDB Length = 268 Score = 43.9 bits (102), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 47/194 (24%), Positives = 81/194 (41%), Gaps = 17/194 (8%) Query: 37 EVLLEKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCA 96 ++L E + G++T+NR NA ++ ++ +L D +I++K A GK F A Sbjct: 5 DLLYEIQDKVGLLTMNRISKHNAFDNQLLTEMRIRLDSAINDTNVRVIVLK-ANGKHFSA 63 Query: 97 GGDIRVISEAEKAKQKIAPVFFREEYM--------LNNAVGSCQKPYVALIHGITMGGGV 148 G D+ + Q +A F EE + L ++ KP +A++ G GGG Sbjct: 64 GADLTWM-------QSMAN-FTEEENLEDSLVLGNLMYSISQSPKPTIAMVQGAAFGGGA 115 Query: 149 GLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGKLGYFLALTGFRLKGRDVY 208 GL+ +A+ F E +GL P V Y + + + L ++ Y Sbjct: 116 GLAAACDIAIASTSARFCFSEVKLGLIPAVISPYVVRAIGERAAKMLFMSAEVFDATRAY 175 Query: 209 RAGIATHFVDSEKL 222 + H V + L Sbjct: 176 SLNLVQHCVPDDTL 189 >4JSB-A nrPDB Length = 296 Score = 43.5 bits (101), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 43/172 (25%), Positives = 71/172 (41%), Gaps = 21/172 (12%) Query: 34 AAEEVLLEKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQD-PETFLIIIKGAGGK 92 AA + L G ITL+RP NA+T M + +L + P+ I++ G Sbjct: 34 AAAGLTLTIDGEVARITLSRPHRRNAMTGRM----WTELARIGHTLPQAVRIVVITGEGP 89 Query: 93 AFCAGGDIRVISEAEKAKQKIAPVFF-----REEYMLNNAVGSCQKPY----------VA 137 F +G D+ + +A K + P L+ + S Q+ + +A Sbjct: 90 TFSSGIDLDMF-QAGKVDGEPTPFTLLARDPNSTAALDQVIASYQEGFLWLRRADIVSIA 148 Query: 138 LIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQG 189 + G +G G L++ R+ ++ M E A+GL PD+ G L L G Sbjct: 149 AVRGHAIGAGFQLALSCDIRILSDTAQLCMKEPALGLVPDLTGTQPLVELVG 200 >1EF9-A nrPDB Length = 261 Score = 42.7 bits (99), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 42/180 (23%), Positives = 74/180 (41%), Gaps = 9/180 (5%) Query: 46 TGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKG-AGGKAFCAGGDIRVIS 104 VI N + LNAL+ I + L + PE II++ +G K F AG DI + Sbjct: 14 VAVIEFNYGRKLNALSKVFIDDLMQALSDLNR-PEIRCIILRAPSGSKVFSAGHDIHELP 72 Query: 105 EAEKAKQKIAPVFFREEY-MLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKC 163 + P+ + + + + KP ++++ G GG + + +A Sbjct: 73 SGGR-----DPLSYDDPLRQITRMIQKFPKPIISMVEGSVWGGAFEMIMSSDLIIAASTS 127 Query: 164 LFAMPETAIGLFPDVGGGYFLPRLQG-KLGYFLALTGFRLKGRDVYRAGIATHFVDSEKL 222 F+M +G+ ++ G + L R G + L T + + GI H V+ E+L Sbjct: 128 TFSMTPVNLGVPYNLVGIHNLTRDAGFHIVKELIFTASPITAQRALAVGILNHVVEVEEL 187 >3HP0-A nrPDB Length = 267 Score = 42.4 bits (98), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 35/151 (23%), Positives = 68/151 (45%), Gaps = 7/151 (4%) Query: 49 ITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRVISEAEK 108 IT +RP+ N + +I + L + E T +++++G + FC G D + I + K Sbjct: 20 ITFHRPEANNTINDTLIEECLQVLNQCETSTVT-VVVLEGLP-EVFCFGADFQEIYQEMK 77 Query: 109 AKQKIAPVFFREEYMLNNAVGSCQKPYVALIH--GITMGGGVGLSVHGQFRVATEKCLFA 166 +K A +E + + + PYV + H G GG+G +A + F+ Sbjct: 78 RGRKQAS---SQEPLYDLWMKLQTGPYVTISHVRGKVNAGGLGFVSATDIAIADQTASFS 134 Query: 167 MPETAIGLFPDVGGGYFLPRLQGKLGYFLAL 197 + E GL+P + + R+ + +++ L Sbjct: 135 LSELLFGLYPACVLPFLIRRIGRQKAHYMTL 165 >4Q1J-A nrPDB Length = 268 Score = 36.2 bits (82), Expect = 0.022, Method: Compositional matrix adjust. Identities = 32/159 (20%), Positives = 69/159 (43%), Gaps = 14/159 (8%) Query: 58 NALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRVISEAEKAKQKIAPVF 117 NA + + + + Q+P+ +I+ G F +GG + ++ K Sbjct: 46 NAFSQELTDDLIQAFEYIRQNPKYKAVILTGYD-NYFASGGTQEGLLRIQQGLTK----- 99 Query: 118 FREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPD 177 F ++ + + A+ C+ P +A + G +GGG + + + + + ++ G P Sbjct: 100 FTDDNLYSLAL-DCEIPVIAAMQGHGIGGGFVMGLFADIVILSRESVYTANFMKYGFTPG 158 Query: 178 VGGGYFLPRLQGKLGYFLA----LTGFRLKGRDVYRAGI 212 +G + +P+ KLG+ LA L +G D+ + G+ Sbjct: 159 MGATFIVPK---KLGFSLAQEILLNAGSYRGADLEKRGV 194 >3M6N-A nrPDB Length = 305 Score = 34.7 bits (78), Expect = 0.067, Method: Compositional matrix adjust. Identities = 29/121 (23%), Positives = 55/121 (45%), Gaps = 7/121 (5%) Query: 85 IIKGAGGKAFCAGGDI----RVISEAEKAKQ-KIAPVFFREEYMLNNAVGSCQKPYVALI 139 ++ + F GGD+ ++I E ++A+ A R + + +G+ + +AL+ Sbjct: 89 VVLASDSDVFNLGGDLALFCQLIREGDRARLLDYAQRCVRGVHAFHVGLGA-RAHSIALV 147 Query: 140 HGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFL-PRLQGKLGYFLALT 198 G +GGG ++ +A E + +PE LFP +G F+ R+ L + L Sbjct: 148 QGNALGGGFEAALSCHTIIAEEGVMMGLPEVLFDLFPGMGAYSFMCQRISAHLAQKIMLE 207 Query: 199 G 199 G Sbjct: 208 G 208 >4B3J-A nrPDB Length = 736 Score = 32.7 bits (73), Expect = 0.28, Method: Compositional matrix adjust. Identities = 27/124 (21%), Positives = 56/124 (45%), Gaps = 7/124 (5%) Query: 43 KGCTGVITL---NRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCAGGD 99 K G++TL + N + I + + + + ++ ++ + K F AGGD Sbjct: 26 KDADGIVTLTMDDPSGSTNVMNEAYIESMGKAVDRLVAEKDSITGVVVASAKKTFFAGGD 85 Query: 100 IRVISEAEKAKQKIAPVFFREEYMLNN--AVGSCQKPYVALIHGITMGGGVGLSVHGQFR 157 ++ + +A + VF E + + + KP VA I+G +GGG+ +++ R Sbjct: 86 VKTMIQARP--EDAGDVFNTVETIKRQLRTLETLGKPVVAAINGAALGGGLEIALACHHR 143 Query: 158 VATE 161 +A + Sbjct: 144 IAAD 147 >2NP9-A nrPDB Length = 440 Score = 32.3 bits (72), Expect = 0.32, Method: Compositional matrix adjust. Identities = 33/162 (20%), Positives = 67/162 (41%), Gaps = 21/162 (12%) Query: 36 EEVLLEKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGA------ 89 E V LE++ +T+ R LNA + + + DP + +++G Sbjct: 167 EAVHLERRDGVARLTMCRDDRLNAEDGQQVDDMETAVDLALLDPGVRVGLLRGGVMSHPR 226 Query: 90 --GGKAFCAGGDIRVISEAEKA------KQKIAPVFFREEYMLNNA-------VGSCQKP 134 G + F AG +++ +S+ + ++++ + +L N +KP Sbjct: 227 YRGKRVFSAGINLKYLSQGGISLVDFLMRRELGYIHKLVRGVLTNDDRPGWWHSPRIEKP 286 Query: 135 YVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFP 176 +VA + G +GGG L + +A+ F++P G+ P Sbjct: 287 WVAAVDGFAIGGGAQLLLVFDRVLASSDAYFSLPAAKEGIIP 328 >4HC8-A nrPDB Length = 255 Score = 31.6 bits (70), Expect = 0.55, Method: Compositional matrix adjust. Identities = 35/142 (24%), Positives = 59/142 (41%), Gaps = 10/142 (7%) Query: 35 AEEVLLEKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAF 94 ++ V +K VI+++ K +NAL M + + + ++D L+I G+ F Sbjct: 4 SDPVSYTRKDSIAVISMDDGK-VNALGPAMQQALNAAIDNADRDDVGALVIT--GNGRVF 60 Query: 95 CAGGDIRVISEAEKAKQKIAPVF--FREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSV 152 G D+++++ E + P R + L + S KP V G + G L Sbjct: 61 SGGFDLKILTSGE-----VQPAIDMLRGGFELAYRLLSYPKPVVMACTGHAIAMGAFLLS 115 Query: 153 HGQFRVATEKCLFAMPETAIGL 174 G RVA E AIG+ Sbjct: 116 CGDHRVAAHAYNIQANEVAIGM 137 >5E7G-A nrPDB Length = 456 Score = 30.4 bits (67), Expect = 1.2, Method: Compositional matrix adjust. Identities = 15/48 (31%), Positives = 29/48 (60%), Gaps = 3/48 (6%) Query: 334 QACMRGHDFHEGVRAVLIDKDQSPK--WKPADLKEVTEEDLNNHFKSL 379 Q + G +F+E V+AV + +Q K +P D++E+T ++NN + + Sbjct: 119 QMTVIGGNFYE-VQAVYLSTEQPAKDGTRPVDVQEITNYEVNNKYSQI 165 >3D31-A nrPDB Length = 348 Score = 30.4 bits (67), Expect = 1.2, Method: Compositional matrix adjust. Identities = 18/64 (28%), Positives = 32/64 (50%) Query: 190 KLGYFLALTGFRLKGRDVYRAGIATHFVDSEKLAMLEEDLLALKSPSKENIASVLENYHT 249 K+ + L L G + R +A V + K+ +L+E L AL ++EN +L H Sbjct: 116 KIEHLLDRNPLTLSGGEQQRVALARALVTNPKILLLDEPLSALDPRTQENAREMLSVLHK 175 Query: 250 ESKI 253 ++K+ Sbjct: 176 KNKL 179 >3GON-A nrPDB Length = 335 Score = 30.0 bits (66), Expect = 1.7, Method: Compositional matrix adjust. Identities = 36/132 (27%), Positives = 58/132 (43%), Gaps = 34/132 (25%) Query: 227 EDLLALKSPSKENIASVLENYHTESKIDRDKSFILEE---------------------HM 265 EDL+ +S ++ +A+ LE + + ++RD F + + HM Sbjct: 157 EDLVLYQSFDRQKVAAWLEEENLATVLERDWGFSISQVKPTLECDFLVGWTKEVAVSSHM 216 Query: 266 -----DKINSCF---SANTVEEIIENLQQDGSSFALEQLKVINK----MSPTSLKITLRQ 313 IN F S TV ++E L+Q S +EQ++V +K +S LRQ Sbjct: 217 VQQIKQNINQNFLTSSKETVVSLVEALEQGKSEKIIEQVEVASKLLEGLSTDIYTPLLRQ 276 Query: 314 LMEGSSKTLQEV 325 L E +S+ LQ V Sbjct: 277 LKE-ASQDLQAV 287 >5AYN-A nrPDB Length = 440 Score = 30.0 bits (66), Expect = 1.9, Method: Compositional matrix adjust. Identities = 37/122 (30%), Positives = 50/122 (40%), Gaps = 25/122 (20%) Query: 79 PETFLI--IIKGAGGKAFCAGGDIRVISEAEKAKQKIAPVFFREEYMLNNAVGSCQKPYV 136 PE FL+ +I+ +G K I+V++EA+ K N GS P Sbjct: 202 PEYFLLRNVIQRSGLK-------IKVLTEAQSWKDTFH----------INLRGSFSDPIF 244 Query: 137 ALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFL------PRLQGK 190 LI + LS HG A K +PET IGLF +G + L P L + Sbjct: 245 WLILSYALLWLSVLSPHGVLLAAYLKDEMRLPETEIGLFRGLGAVFGLISTVSFPYLVRR 304 Query: 191 LG 192 LG Sbjct: 305 LG 306 >1XX4-A nrPDB Length = 261 Score = 29.3 bits (64), Expect = 2.8, Method: Compositional matrix adjust. Identities = 33/152 (21%), Positives = 66/152 (43%), Gaps = 26/152 (17%) Query: 36 EEVLLEKKGCTGVITL---NRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGK 92 + VL+EK+G G+ + N P +N+L+L + + L+K E D +I+ Sbjct: 4 KRVLVEKEGEAGIAVMKFKNPP--VNSLSLEFLTEFVISLEKLENDKSIRGVILTSERPG 61 Query: 93 AFCAGGDIRVI--------SEAEKAKQKIAPVFFREEYMLNNAVGSCQKPYVALIHGITM 144 F AG D+ + +E KA Q++ + L ++ I+G + Sbjct: 62 IFSAGLDLMEMYGRNPAHYAEYWKAVQELWLRLYLSNLTL-----------ISAINGASP 110 Query: 145 GGGVGLSVHGQFRVATE--KCLFAMPETAIGL 174 GG +++ +R+ + K + E+ +G+ Sbjct: 111 AGGCLMALTCDYRIMADNSKYTIGLNESLLGI 142 >3GYX-A nrPDB Length = 662 Score = 29.3 bits (64), Expect = 2.8, Method: Compositional matrix adjust. Identities = 18/55 (32%), Positives = 25/55 (45%), Gaps = 8/55 (14%) Query: 202 LKGRDVYRAGIATHFVDSEKL--------AMLEEDLLALKSPSKENIASVLENYH 248 +K D Y G+ T++ S+ L MLEED L L + + ENYH Sbjct: 543 IKCTDEYGGGVGTYYNTSKALLDTGFWLMEMLEEDSLKLAARDLHELLRCWENYH 597 >2J49-A nrPDB Length = 148 Score = 28.9 bits (63), Expect = 4.3, Method: Compositional matrix adjust. Identities = 19/56 (33%), Positives = 30/56 (53%), Gaps = 4/56 (7%) Query: 264 HMDKINSCFSANTVEEIIENLQQDGSSFALEQLKVINKMSPTSLKITLRQLMEGSS 319 H +IN FS N+++ I EN + S+F + ++ MS T+L + L L E S Sbjct: 70 HGSEINRLFSVNSIDHIKEN--EVASAFQSHKYRI--TMSKTTLNLLLYFLNENES 121 >6DBY-A nrPDB Length = 150 Score = 28.1 bits (61), Expect = 6.0, Method: Compositional matrix adjust. Identities = 21/71 (29%), Positives = 32/71 (45%), Gaps = 12/71 (16%) Query: 288 GSSFALEQLKVINKMSPTSLKITLRQLMEGSSKTLQEVLTMEYRLSQACMRGHDFHEGVR 347 G SF E+ M T LKI +L+ ++ +E T + +S + +R Sbjct: 49 GESF--EECAAREVMEETGLKIEKMKLLTVTNNVFKEAPTPSHYVSVS----------IR 96 Query: 348 AVLIDKDQSPK 358 AVL+D Q PK Sbjct: 97 AVLVDPSQEPK 107 >5BPW-A nrPDB Length = 843 Score = 28.1 bits (61), Expect = 7.0, Method: Compositional matrix adjust. Identities = 18/65 (27%), Positives = 29/65 (44%), Gaps = 6/65 (9%) Query: 28 MSKHTDAAEEVLLEKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIK 87 + +HTD ++ V G+I + F A T + R IY L D ET +++K Sbjct: 601 LRRHTDISQSV------SNGLIAIKFGSFTYATTEKVRRSIYSCLDAQFYDDETVTVVLK 654 Query: 88 GAGGK 92 G+ Sbjct: 655 DTVGR 659 >4MOW-A nrPDB Length = 256 Score = 27.7 bits (60), Expect = 8.5, Method: Compositional matrix adjust. Identities = 11/39 (28%), Positives = 22/39 (56%) Query: 89 AGGKAFCAGGDIRVISEAEKAKQKIAPVFFREEYMLNNA 127 AGG+A GGD+ ++A++ + R + ++NN+ Sbjct: 62 AGGRAVAVGGDVSKAADAQRIVDTAIETYGRLDVLVNNS 100 >6BYQ-A nrPDB Length = 410 Score = 27.7 bits (60), Expect = 8.6, Method: Compositional matrix adjust. Identities = 31/98 (31%), Positives = 45/98 (45%), Gaps = 12/98 (12%) Query: 237 KENIAS-VLENYHTESKIDRDKSFILEEHMDKINSCFSANTVEEIIENLQQDGSSFALEQ 295 KE++A ++ Y+ D D++F +E K+ FSAN + EI+ D L+ Sbjct: 303 KEDLAGEIVARYY-----DNDQAFKAKEQFSKV---FSANLLPEILSESDFDEGVGILDV 354 Query: 296 LKVINKMSPTSLKITLRQLMEGSSKTLQEVLTME-YRL 332 LK I TS R + G K QEV+ E YR Sbjct: 355 LKQIGFCPSTSQ--ARRDIQGGGVKINQEVIKDESYRF 390 >1GEE-A nrPDB Length = 261 Score = 27.7 bits (60), Expect = 8.8, Method: Compositional matrix adjust. Identities = 17/52 (32%), Positives = 25/52 (48%) Query: 76 EQDPETFLIIIKGAGGKAFCAGGDIRVISEAEKAKQKIAPVFFREEYMLNNA 127 E + + L IK GG+A GD+ V S+ Q F + + M+NNA Sbjct: 42 EDEANSVLEEIKKVGGEAIAVKGDVTVESDVINLVQSAIKEFGKLDVMINNA 93 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 3BPT-A nrPDB 492 e-139 4HDT-A nrPDB 334 4e-92 4J2U-A nrPDB 331 3e-91 5MRE-88 nrPDB 304 4e-83 3JU1-A nrPDB 303 1e-82 5Z7R-A nrPDB 262 1e-70 5ZAI-A nrPDB 243 7e-65 2IEX-A nrPDB 228 4e-60 2DUB-A nrPDB 225 2e-59 2HW5-A nrPDB 225 3e-59 5WYB-B nrPDB 213 1e-55 4EML-A nrPDB 213 1e-55 3H81-A nrPDB 212 2e-55 3T88-A nrPDB 210 9e-55 2UZF-A nrPDB 208 5e-54 5YLO-A nrPDB 203 8e-53 5ZRV-A nrPDB 203 1e-52 4FZW-A nrPDB 201 5e-52 3MOY-A nrPDB 201 6e-52 5JBW-A nrPDB 195 3e-50 6OJM-A nrPDB 191 5e-49 4JWV-A nrPDB 190 1e-48 4JCS-A nrPDB 184 4e-47 4IZC-A nrPDB 184 6e-47 2VSU-C nrPDB 184 7e-47 3T8B-A nrPDB 182 3e-46 4ZU2-A nrPDB 179 3e-45 5KJP-A nrPDB 171 4e-43 5VE2-A nrPDB 171 5e-43 3I47-A nrPDB 171 5e-43 1EF9-A nrPDB 170 1e-42 2PPY-A nrPDB 169 1e-42 1NZY-B nrPDB 169 2e-42 3HIN-A nrPDB 169 2e-42 3OME-A nrPDB 167 8e-42 6IUM-B nrPDB 166 1e-41 4FZW-C nrPDB 164 6e-41 2D3T-A nrPDB 162 2e-40 2WTB-A nrPDB 161 4e-40 4JFC-A nrPDB 157 6e-39 3ZWA-A nrPDB 157 7e-39 2A81-A nrPDB 151 4e-37 4JSB-A nrPDB 148 3e-36 3HP0-A nrPDB 147 8e-36 3HE2-A nrPDB 147 1e-35 Sequences not found previously or not previously below threshold: 3LAO-A nrPDB 125 4e-29 1XX4-A nrPDB 120 8e-28 2NP9-A nrPDB 118 4e-27 4B3J-A nrPDB 105 3e-23 4Q1J-A nrPDB 97 9e-21 4HC8-A nrPDB 91 1e-18 3M6N-A nrPDB 86 2e-17 4ZDC-A nrPDB 79 2e-15 1ON3-A nrPDB 35 0.040 3RZZ-A nrPDB 34 0.12 3U9S-B nrPDB 34 0.15 3BF0-A nrPDB 32 0.34 2V8U-A nrPDB 32 0.52 5XXB-G nrPDB 30 1.3 2YV2-A nrPDB 30 1.3 3GTD-A nrPDB 30 1.7 1SKF-A nrPDB 30 2.2 4Q0G-A nrPDB 30 2.5 2C82-A nrPDB 28 9.4 >3BPT-A nrPDB Length = 363 Score = 492 bits (1266), Expect = e-139, Method: Composition-based stats. Identities = 354/355 (99%), Positives = 354/355 (99%) Query: 32 TDAAEEVLLEKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGG 91 TDAAEEVLL KKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGG Sbjct: 2 TDAAEEVLLGKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGG 61 Query: 92 KAFCAGGDIRVISEAEKAKQKIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLS 151 KAFCAGGDIRVISEAEKAKQKIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLS Sbjct: 62 KAFCAGGDIRVISEAEKAKQKIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLS 121 Query: 152 VHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGKLGYFLALTGFRLKGRDVYRAG 211 VHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGKLGYFLALTGFRLKGRDVYRAG Sbjct: 122 VHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGKLGYFLALTGFRLKGRDVYRAG 181 Query: 212 IATHFVDSEKLAMLEEDLLALKSPSKENIASVLENYHTESKIDRDKSFILEEHMDKINSC 271 IATHFVDSEKLAMLEEDLLALKSPSKENIASVLENYHTESKIDRDKSFILEEHMDKINSC Sbjct: 182 IATHFVDSEKLAMLEEDLLALKSPSKENIASVLENYHTESKIDRDKSFILEEHMDKINSC 241 Query: 272 FSANTVEEIIENLQQDGSSFALEQLKVINKMSPTSLKITLRQLMEGSSKTLQEVLTMEYR 331 FSANTVEEIIENLQQDGSSFALEQLKVINKMSPTSLKITLRQLMEGSSKTLQEVLTMEYR Sbjct: 242 FSANTVEEIIENLQQDGSSFALEQLKVINKMSPTSLKITLRQLMEGSSKTLQEVLTMEYR 301 Query: 332 LSQACMRGHDFHEGVRAVLIDKDQSPKWKPADLKEVTEEDLNNHFKSLGSSDLKF 386 LSQACMRGHDFHEGVRAVLIDKDQSPKWKPADLKEVTEEDLNNHFKSLGSSDLKF Sbjct: 302 LSQACMRGHDFHEGVRAVLIDKDQSPKWKPADLKEVTEEDLNNHFKSLGSSDLKF 356 >4HDT-A nrPDB Length = 353 Score = 334 bits (856), Expect = 4e-92, Method: Composition-based stats. Identities = 134/352 (38%), Positives = 195/352 (55%), Gaps = 13/352 (3%) Query: 36 EEVLLEKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFC 95 E+VL+ +G G++TLNRPK +N+LT M+ + +L WE D +++ GAG + C Sbjct: 9 EDVLVNVEGGVGLLTLNRPKAINSLTHGMVTTMAERLAAWENDDSVRAVLLTGAGERGLC 68 Query: 96 AGGDIRVISEAEKAKQKIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQ 155 AGGD+ I + KA A F+ +EY LN +G KPYV+++ GI MGGGVG+ HG Sbjct: 69 AGGDVVAIYHSAKADGAEARRFWFDEYRLNAHIGRYPKPYVSIMDGIVMGGGVGVGAHGN 128 Query: 156 FRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGKLGYFLALTGFRLKGRDVYRAGIATH 215 RV T+ AMPE IG PDVGG Y L R GKLG ALTG G D G A H Sbjct: 129 VRVVTDTTKMAMPEVGIGFIPDVGGTYLLSRAPGKLGLHAALTGAPFSGADAIVMGFADH 188 Query: 216 FVDSEKLAMLEEDLLALKSPSKENIASVLENYHTESKIDRDKSFILEEHMDKINSCFSAN 275 +V +K+ ++A + + + L + E + L E I+ C++ + Sbjct: 189 YVPHDKIDEFTRAVIA------DGVDAALAAHAQE-----PPASPLAEQRSWIDECYTGD 237 Query: 276 TVEEIIENLQQDGSSFALEQLKVINKMSPTSLKITLRQLMEGSS-KTLQEVLTMEYRLSQ 334 TV +II L+ + A E +I SP +L +TL + + ++L++ L EYR+S Sbjct: 238 TVADIIAALRAHDAPAAGEAADLIATRSPIALSVTLESVRRAAKLQSLEDTLRQEYRVSC 297 Query: 335 ACMRGHDFHEGVRAVLIDKDQSPKWKPADLKEVTEEDLNNHFKSLGSSDLKF 386 A ++ HD EG+RA L+DKD++PKW+PA L EVTE D+ +F + L F Sbjct: 298 ASLKSHDLVEGIRAQLVDKDRNPKWRPATLAEVTEADVEAYFAPVDPE-LTF 348 >4J2U-A nrPDB Length = 365 Score = 331 bits (849), Expect = 3e-91, Method: Composition-based stats. Identities = 131/362 (36%), Positives = 190/362 (52%), Gaps = 26/362 (7%) Query: 31 HTDAAEEVLLEKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAG 90 + + +VL+ K G ITL+RP LNALT M+++I L+ W DPE L++I G Sbjct: 19 YFQSMSDVLIRKVRRAGRITLSRPAALNALTCAMVQEIDAALRGWIGDPEVELVVIDAEG 78 Query: 91 GKAFCAGGDIRVI-SEAEKAKQKIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVG 149 +AFCAGGDI + F+R EY +N+ + + KP V+L+ G TMGGGVG Sbjct: 79 PRAFCAGGDIAELHGRGVAGDHAFGQDFWRVEYRMNDRIAAFPKPIVSLMQGFTMGGGVG 138 Query: 150 LSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGKLGYFLALTGFRLKGRDVYR 209 L H + R+ E +MPE AIGL PDVGG + L R G++G +L LTG R+ D Sbjct: 139 LGCHARHRIVGETSQISMPECAIGLVPDVGGTHLLARAPGRIGVWLGLTGARMGPGDAIF 198 Query: 210 AGIATHFVD----SEKLAMLEEDLLALKSPSKENIASVLENYHTESKIDRDKSFILEEHM 265 AG A FV + +A LE LAL ++ E ++ +L++ + Sbjct: 199 AGFADRFVPEADWPDLIAALEGGDLALP-----------DHAAPEGRLP-----VLQDEI 242 Query: 266 DKINSCFSANTVEEIIENLQQDGSSFALEQLKVINKMSPTSLKITLRQLME-GSSKTLQE 324 D++ A T+ EI L+ + A E LK + + SP +L TL L G S ++E Sbjct: 243 DRLF----AGTLAEIPARLEATDTPLAAEALKALRRSSPLALAATLEILQRLGPSAGIRE 298 Query: 325 VLTMEYRLSQACMRGHDFHEGVRAVLIDKDQSPKWKPADLKEVTEEDLNNHFKSLGSSDL 384 L +EYR + DF EG+RA +IDKD+SP+W+ D + V E++ + LG L Sbjct: 299 ALDLEYRFTYRAQGQADFLEGIRAAIIDKDRSPRWRHGDPEAVRPEEVASLLAPLGPQAL 358 Query: 385 KF 386 F Sbjct: 359 TF 360 >5MRE-88 nrPDB Length = 457 Score = 304 bits (779), Expect = 4e-83, Method: Composition-based stats. Identities = 122/351 (34%), Positives = 183/351 (52%), Gaps = 28/351 (7%) Query: 35 AEEVLLEKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAG-GKA 93 A VL + VITLNRPK LNAL M ++ L ++ + T L+I+K + ++ Sbjct: 1 APPVLFTVQDTARVITLNRPKKLNALNAEMSESMFKTLNEYAKSDTTNLVILKSSNRPRS 60 Query: 94 FCAGGDIRVISEAEKAKQKIAPV-FFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSV 152 FCAGGD+ ++ K+ + FF +EY LN + + KP V + GITMGGGVGLS+ Sbjct: 61 FCAGGDVATVAIFNFNKEFAKSIKFFTDEYSLNFQIATYLKPIVTFMDGITMGGGVGLSI 120 Query: 153 HGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQ------GKLGYFLALTGFRLKGRD 206 H FR+ATE +AMPE IG FPDVG + LPR+ ++ +L LTG + G D Sbjct: 121 HTPFRIATENTKWAMPEMDIGFFPDVGSTFALPRIVTLANSNSQMALYLCLTGEVVTGAD 180 Query: 207 VYRAGIATHFVDSEKLAMLEEDLLALKSPSKENIASVLENYHTESKIDR-----DKSFIL 261 Y G+A+H+V SE L L++ L + P + S ID K ++ Sbjct: 181 AYMLGLASHYVSSENLDALQKRLGEISPPFNNDPQSAYFFGMVNESIDEFVSPLPKDYVF 240 Query: 262 E---EHMDKINSCFSA---NTVEEIIENLQQ-----DGSSFALEQLKVINKMSPTSLKIT 310 + E ++ I +CF+ T+E+I+ NL+Q +G +FA E + SP+SL+I Sbjct: 241 KYSNEKLNVIEACFNLSKNGTIEDIMNNLRQYEGSAEGKAFAQEIKTKLLTKSPSSLQIA 300 Query: 311 LRQLMEGSSKTLQEVLTME-YRLSQACMRGH---DFHEGVRAVLIDKDQSP 357 LR + E S ++ + + Y + CM +F E + LIDK + P Sbjct: 301 LRLVQENSRDHIESAIKRDLYTAANMCMNQDSLVEFSEATKHKLIDKQRVP 351 >3JU1-A nrPDB Length = 407 Score = 303 bits (775), Expect = 1e-82, Method: Composition-based stats. Identities = 117/347 (33%), Positives = 185/347 (53%), Gaps = 19/347 (5%) Query: 46 TGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRVISE 105 GV+TLN K LNAL L+M+R + QL W++DP +++ G+G KAFCAGGD+R + Sbjct: 52 VGVVTLNVEKALNALDLDMVRAMTVQLNLWKKDPLIACVVLDGSGEKAFCAGGDVRALYH 111 Query: 106 AEKAKQ----KIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATE 161 A A + ++A VFF EEY L+ + + KP + GI MGGG+GL +V TE Sbjct: 112 ASVAAKGQVTEVAKVFFEEEYRLDYLLHTYGKPVLVWGDGIVMGGGLGLMAGASHKVVTE 171 Query: 162 KCLFAMPETAIGLFPDVGGGYFLPRLQGKLGYFLALTGFRLKGRDVYRAGIATHFVDSEK 221 AMPE IGL+PDVGG YFL R+ GK+G FL LT + + D G+A H+++ + Sbjct: 172 TSRIAMPEVTIGLYPDVGGSYFLNRMPGKMGLFLGLTAYHMNAADACYVGLADHYLNRDD 231 Query: 222 LAMLEEDLLALKS-----PSKENIASVLENYHTESKIDRDKSFILE--EHMDKINSCFSA 274 ++ + + L + + + +++ + I + S + E E +D++ A Sbjct: 232 KELMFDAMATLDWSDSPALNHQRLDTMINELSNQVDIPKGDSVLAESQEMIDRL----MA 287 Query: 275 NTVEEIIENLQQDGSSFAL--EQLKVINKMSPTSLKITLRQLMEGSSKTLQEVLTMEYRL 332 ++ +I+ + + A + + SP S + Q G+ +L + E + Sbjct: 288 GSLTDIVTRMSTLSTDEAWLSKACATMLAGSPISWHLAYIQTQLGTKLSLAQCFKWELTV 347 Query: 333 S-QACMRGHDFHEGVRAVLIDKDQSPKWKPADLKEVTEEDLNNHFKS 378 S C +G DF EGVRA+LIDKD+ PKW+ AD++ V + + S Sbjct: 348 SVNVCAKG-DFCEGVRALLIDKDKQPKWQFADVQSVPNSVIEDILTS 393 >5Z7R-A nrPDB Length = 267 Score = 262 bits (670), Expect = 1e-70, Method: Composition-based stats. Identities = 68/250 (27%), Positives = 110/250 (44%), Gaps = 5/250 (2%) Query: 36 EEVLLEKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFC 95 V+LEK+G V+T+NRPK LNAL + ++++ + + E D E +I+ GAG K+F Sbjct: 4 NNVILEKEGKVAVVTINRPKALNALNSDTLKEMDYVIGEIENDSEVLAVILTGAGEKSFV 63 Query: 96 AGGDIRVISEAEKAKQKIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQ 155 AG DI + E F + + +KP +A ++G +GGG +++ Sbjct: 64 AGADISEMKEMNTI---EGRKFGILGNKVFRRLELLEKPVIAAVNGFALGGGCEIAMSCD 120 Query: 156 FRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGK-LGYFLALTGFRLKGRDVYRAGIAT 214 R+A+ F PE +G+ P GG L RL G + L T +K + R G+ Sbjct: 121 IRIASSNARFGQPEVGLGITPGFGGTQRLSRLVGMGMAKQLIFTAQNIKADEALRIGLVN 180 Query: 215 HFVDSEKLAMLEEDLLALKSPSKENIASVLENYHTESKIDRDKSFILEEHMDKINSCFSA 274 V+ +L M +A K S +A L + D L + CFS Sbjct: 181 KVVEPSEL-MNTAKEIANKIVSNAPVAVKLSKQAINRGMQCDIDTALAFESEAFGECFST 239 Query: 275 NTVEEIIENL 284 ++ + Sbjct: 240 EDQKDAMTAF 249 >5ZAI-A nrPDB Length = 259 Score = 243 bits (621), Expect = 7e-65, Method: Composition-based stats. Identities = 77/261 (29%), Positives = 123/261 (47%), Gaps = 7/261 (2%) Query: 36 EEVLLEKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFC 95 E + +K+G ITLNRP LNAL ++ ++ + + E DPE +III G G KAFC Sbjct: 4 ETIETKKEGNLFWITLNRPDKLNALNAKLLEELDRAVSQAESDPEIRVIIITGKG-KAFC 62 Query: 96 AGGDIRVISEAEKAKQKIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQ 155 AG DI ++ A A F ++ + + + + KP +A+I+G +GGG+ L++ Sbjct: 63 AGADITQFNQLTPA---EAWKFSKKGREIMDKIEALSKPTIAMINGYALGGGLELALACD 119 Query: 156 FRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGK-LGYFLALTGFRLKGRDVYRAGIAT 214 R+A E+ +PE +G++P GG L R+ GK + +TG R+ G+D + G+ Sbjct: 120 IRIAAEEAQLGLPEINLGIYPGYGGTQRLTRVIGKGRALEMMMTGDRIPGKDAEKYGLVN 179 Query: 215 HFVDSEKLAMLEEDLLALKSPSKENIASVLENYHTESKIDRDKSFILEEHMDKINSCFSA 274 V L E LA K K I+ L +D L FS Sbjct: 180 RVVPLANLEQ-ETRKLAEKIAKKSPISLALIKEVVNRGLDSPLLSGLALESVGWGVVFST 238 Query: 275 -NTVEEIIENLQQDGSSFALE 294 + E + L++ +F + Sbjct: 239 EDKKEGVSAFLEKREPTFKGK 259 >2IEX-A nrPDB Length = 272 Score = 228 bits (580), Expect = 4e-60, Method: Composition-based stats. Identities = 55/227 (24%), Positives = 87/227 (38%), Gaps = 7/227 (3%) Query: 25 HLRMSKHTDAAEEVLLEKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLI 84 K D E+++ E IT+NRP+ NA + ++ K D +I Sbjct: 2 PFEWVKQYD-YEDIIYETYNGIAKITINRPEVHNAFRPKTVNEMIDAFTKARDDSNIGVI 60 Query: 85 IIKGAGGKAFCAGGDIRVISEAEKAKQKIAPVFFREEYMLNNAVGSCQKPYVALIHGITM 144 I+ GAGGKAFC+GGD +V + P + L + KP +A++ G + Sbjct: 61 ILTGAGGKAFCSGGDQKVRGHGGYVGEDEIPRLNVLD--LQRLIRVIPKPVIAMVAGYAI 118 Query: 145 GGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQG-KLGYFLALTGFRLK 203 GGG L V +A + +F +G F G +L R+ G K + + Sbjct: 119 GGGHVLHVVCDLTIAADNAIFGQTGPKVGSFDGGYGAGYLARIVGHKKAREIWYLCRQYT 178 Query: 204 GRDVYRAGIATHFVDSEKLAMLEEDLLA---LKSPSKENIASVLENY 247 ++ G+ V E+L KSP+ N Sbjct: 179 AQEALEMGLVNKVVPLEQLEEETVKWAQEILEKSPTAIRFLKAAFNA 225 >2DUB-A nrPDB Length = 261 Score = 225 bits (574), Expect = 2e-59, Method: Composition-based stats. Identities = 68/223 (30%), Positives = 105/223 (47%), Gaps = 11/223 (4%) Query: 36 EEVLLEKKGC---TGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGK 92 + ++ EKKG G+I LNRPK LNAL +I ++ L+ +E+DP I++ G G K Sbjct: 5 QYIITEKKGKNSSVGLIQLNRPKALNALCNGLIEELNQALETFEEDPAVGAIVLTG-GEK 63 Query: 93 AFCAGGDIRVISEAEKAKQKIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSV 152 AF AG DI+ + + Q F + + + +KP +A ++G +GGG L++ Sbjct: 64 AFAAGADIKEMQ--NRTFQDCYSGKFLSHW---DHITRIKKPVIAAVNGYALGGGCELAM 118 Query: 153 HGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGK-LGYFLALTGFRLKGRDVYRAG 211 A EK F PE +G P GG L R GK L + LTG R+ +D +AG Sbjct: 119 MCDIIYAGEKAQFGQPEILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAG 178 Query: 212 IATHFVDSEKLAMLEEDLLALKSPSKENIASVLENYHTESKID 254 + + E L + E A K + I + + + Sbjct: 179 LVSKIFPVETL-VEEAIQCAEKIANNSKIIVAMAKESVNAAFE 220 >2HW5-A nrPDB Length = 286 Score = 225 bits (573), Expect = 3e-59, Method: Composition-based stats. Identities = 73/253 (28%), Positives = 112/253 (44%), Gaps = 11/253 (4%) Query: 36 EEVLLEKKGC---TGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGK 92 E ++ EK+G G+I LNRPK LNAL +I ++ LK +E+DP I++ G G K Sbjct: 30 EYIIAEKRGKNNTVGLIQLNRPKALNALCDGLIDELNQALKIFEEDPAVGAIVLTG-GDK 88 Query: 93 AFCAGGDIRVISEAEKAKQKIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSV 152 AF AG DI+ + + + + + +KP +A ++G GGG L++ Sbjct: 89 AFAAGADIKEMQ-----NLSFQDCYSSKFLKHWDHLTQVKKPVIAAVNGYAFGGGCELAM 143 Query: 153 HGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGK-LGYFLALTGFRLKGRDVYRAG 211 A EK FA PE IG P GG L R GK L + LTG R+ +D +AG Sbjct: 144 MCDIIYAGEKAQFAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAG 203 Query: 212 IATHFVDSEKLAMLEEDLLALKSPSKENIASVLENYHTESKIDRDKSFILEEHMDKINSC 271 + + E L + E A K S I + + + + + S Sbjct: 204 LVSKICPVETL-VEEAIQCAEKIASNSKIVVAMAKESVNAAFEMTLTEGSKLEKKLFYST 262 Query: 272 FSANTVEEIIENL 284 F+ + +E + Sbjct: 263 FATDDRKEGMTAF 275 >5WYB-B nrPDB Length = 280 Score = 213 bits (542), Expect = 1e-55, Method: Composition-based stats. Identities = 69/273 (25%), Positives = 122/273 (44%), Gaps = 8/273 (2%) Query: 19 TNTILHHLRMSKHTDAAEEVLLEKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQD 78 NT + + S D ++ +EK G T +IT+N P N + + + ++ +D Sbjct: 1 MNTAVEPYKASSFDDT-HKLTVEKHGHTALITINHPPA-NTWDRDSLIGLRQLIEHLNRD 58 Query: 79 PETFLIIIKGAGGKAFCAGGDIRVISEAEKAKQKIAPVFFREEYMLNNAVGSCQKPYVAL 138 + + +++ G G K F AG D+ + ++ +KA+ + F E + A+ + +A Sbjct: 59 DDIYALVVTGQGPKFFSAGADLNMFADGDKARAREMARRFGEAF---EALRDFRGVSIAA 115 Query: 139 IHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGK-LGYFLAL 197 I+G MGGG+ ++ R+A + A+PE A+GL P GG LP L G+ + L Sbjct: 116 INGYAMGGGLECALACDIRIAERQAQMALPEAAVGLLPCAGGTQALPWLVGEGWAKRMIL 175 Query: 198 TGFRLKGRDVYRAGIATHFVDSEKLAMLEEDLLALKSPSKENIASVLENYHTESKIDRDK 257 R+ R G+ VDS + A LLA K + +A + +R Sbjct: 176 CNERVDAETALRIGLVEQVVDSGE-ARGAALLLAAKVARQSPVAIRTIKPLIQGARERAP 234 Query: 258 SFILEEHMDKINSCFSA-NTVEEIIENLQQDGS 289 + L E ++ F A +T E + L++ Sbjct: 235 NTWLPEERERFVDLFDAQDTREGVNAFLEKRDP 267 >4EML-A nrPDB Length = 275 Score = 213 bits (541), Expect = 1e-55, Method: Composition-based stats. Identities = 57/242 (23%), Positives = 96/242 (39%), Gaps = 14/242 (5%) Query: 28 MSKHTDAAEEVLLEKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIK 87 ++KH D ++L K G I +NRP NA + ++Y +D ++++ Sbjct: 5 IAKHYD---DILYYKAGGIAKIVINRPHKRNAFRPQTVFELYDAFCNAREDNRIGVVLLT 61 Query: 88 GAGGK-----AFCAGGDIRVISEAEKAKQKIAPVFFREEYMLNNAVGSCQKPYVALIHGI 142 GAG AFC+GGD V E + P + L + S K +AL+ G Sbjct: 62 GAGPHSDGKYAFCSGGDQSVRGEGGYIDDQGTPRLNVLD--LQRLIRSMPKVVIALVAGY 119 Query: 143 TMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGK-LGYFLALTGFR 201 +GGG L + +A + +F +G F G +L R+ G+ + + Sbjct: 120 AIGGGHVLHLVCDLTIAADNAIFGQTGPKVGSFDGGFGSSYLARIVGQKKAREIWYLCRQ 179 Query: 202 LKGRDVYRAGIATHFVDSEKLAMLEEDLLALKSPSKENIASVLENYHTESKIDRDKSFIL 261 ++ R G+ V ++L E A + SK +A + D D L Sbjct: 180 YSAQEAERMGMVNTVVPVDRLEE-EGIQWAKEILSKSPLAIRCLKAAFNA--DCDGQAGL 236 Query: 262 EE 263 +E Sbjct: 237 QE 238 >3H81-A nrPDB Length = 278 Score = 212 bits (540), Expect = 2e-55, Method: Composition-based stats. Identities = 64/258 (24%), Positives = 112/258 (43%), Gaps = 8/258 (3%) Query: 34 AAEEVLLEKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKA 93 E +L+E+ G+ITLNRP+ LNAL ++ ++ + + DP+ III G+ KA Sbjct: 23 TYETILVERDQRVGIITLNRPQALNALNSQVMNEVTSAATELDDDPDIGAIIITGSA-KA 81 Query: 94 FCAGGDIRVISEAEKAKQKIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVH 153 F AG DI+ +++ A F + + + + + P +A + G +GGG L++ Sbjct: 82 FAAGADIKEMADLTFAD-----AFTADFFATWGKLAAVRTPTIAAVAGYALGGGCELAMM 136 Query: 154 GQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGKL-GYFLALTGFRLKGRDVYRAGI 212 +A + F PE +G+ P +GG L R GK L LTG + + R+G+ Sbjct: 137 CDVLIAADTAKFGQPEIKLGVLPGMGGSQRLTRAIGKAKAMDLILTGRTMDAAEAERSGL 196 Query: 213 ATHFVDSEKLAMLEEDLLALKSPSKENIASVLENYHTESKIDRDKSFILEEHMDKINSCF 272 + V ++ L + E A A+ + + S L +S F Sbjct: 197 VSRVVPADDL-LTEARATATTISQMSASAARMAKEAVNRAFESSLSEGLLYERRLFHSAF 255 Query: 273 SANTVEEIIENLQQDGSS 290 + E + + + Sbjct: 256 ATEDQSEGMAAFIEKRAP 273 >3T88-A nrPDB Length = 289 Score = 210 bits (534), Expect = 9e-55, Method: Composition-based stats. Identities = 47/196 (23%), Positives = 79/196 (40%), Gaps = 3/196 (1%) Query: 36 EEVLLEKK-GCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAF 94 E++ EK IT+NRP+ NA ++++ L D +II+ GAG KAF Sbjct: 27 EDIRYEKSTDGIAKITINRPQVRNAFRPLTVKEMIQALADARYDDNIGVIILTGAGDKAF 86 Query: 95 CAGGDIRVISEAEKAKQKIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHG 154 C+GGD +V + K V + +C KP VA++ G ++GGG L + Sbjct: 87 CSGGDQKVRGDYGGYKDDSG-VHHLNVLDFQRQIRTCPKPVVAMVAGYSIGGGHVLHMMC 145 Query: 155 QFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGK-LGYFLALTGFRLKGRDVYRAGIA 213 +A + +F +G F G ++ R+ G+ + + + G+ Sbjct: 146 DLTIAADNAIFGQTGPKVGSFDGGWGASYMARIVGQKKAREIWFLCRQYDAKQALDMGLV 205 Query: 214 THFVDSEKLAMLEEDL 229 V L Sbjct: 206 NTVVPLADLEKETVRW 221 >2UZF-A nrPDB Length = 273 Score = 208 bits (528), Expect = 5e-54, Method: Composition-based stats. Identities = 45/220 (20%), Positives = 81/220 (36%), Gaps = 4/220 (1%) Query: 36 EEVLLEKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFC 95 +E+ E +T+NRP+ NA T + ++ + D +I++ G G AFC Sbjct: 13 DEIKYEFYEGIAKVTINRPEVRNAFTPKTVAEMIDAFSRARDDQNVSVIVLTGEGDLAFC 72 Query: 96 AGGDIRVISEAEKAKQKIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQ 155 +GGD + + P + L + KP +A++ G +GGG L+V Sbjct: 73 SGGDQKKRGHGGYVGEDQIPRLNVLD--LQRLIRIIPKPVIAMVKGYAVGGGNVLNVVCD 130 Query: 156 FRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQG-KLGYFLALTGFRLKGRDVYRAGIAT 214 +A + +F +G F G +L R+ G K + + ++ G+ Sbjct: 131 LTIAADNAIFGQTGPKVGSFDAGYGSGYLARIVGHKKAREIWYLCRQYNAQEALDMGLVN 190 Query: 215 HFVDSEKLAMLEEDLLALKSPSKENIASVLENYHTESKID 254 V EK+ + A + D Sbjct: 191 TVVPLEKVEDETVQW-CKEIMKHSPTALRFLKAAMNADTD 229 >5YLO-A nrPDB Length = 271 Score = 203 bits (517), Expect = 8e-53, Method: Composition-based stats. Identities = 72/323 (22%), Positives = 127/323 (39%), Gaps = 68/323 (21%) Query: 37 EVLLEKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCA 96 + + + LNRP+ NAL + + ++ +L E+DP +++ G+G ++FCA Sbjct: 6 PLQTRVEAGIAWLVLNRPQQRNALDIPTLEALHVRLDACERDPAVRAVVLGGSG-RSFCA 64 Query: 97 GGDIRVISEAEKAKQKIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQF 156 G D+ + AE + + + + L + + KP VA ++G +G G+ L++ F Sbjct: 65 GADLAEWAAAEARGELESYGWTEAAHALMGRLHALDKPTVAAVNGSAVGAGMDLALCCDF 124 Query: 157 RVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGKLGYFLALTGFRLKGRDVYRAGIATHF 216 R+A F T + PD G + LPRL G Sbjct: 125 RIAAASARFKAGYTGMAYCPDAGASWHLPRLLGSEA------------------------ 160 Query: 217 VDSEKLAMLEEDLLALKSPSKENIASVLENYHTESKIDRDKSFILEEHMDKINSCFSANT 276 +++L L+E A ++ + V + +EH+ + F+A Sbjct: 161 --AKRLLFLDEAWSAERALGAGLVGEV----------------VADEHLVEAVGAFAARL 202 Query: 277 VEEIIENLQQDGSSFALEQLKVINKMSPTSLKITLRQLMEGSSKTLQEVLTMEYRLSQAC 336 G +FA Q K R L +G+ ++L E L E C Sbjct: 203 ---------ASGPTFAFAQTK--------------RLLRDGAGRSLAEQLRAEQAAGLLC 239 Query: 337 MRGHDFHEGVRAVLIDKDQSPKW 359 R D E +RAV + +SP++ Sbjct: 240 GRSEDAAEALRAVA--EKRSPQF 260 >5ZRV-A nrPDB Length = 763 Score = 203 bits (516), Expect = 1e-52, Method: Composition-based stats. Identities = 50/218 (22%), Positives = 96/218 (44%), Gaps = 9/218 (4%) Query: 9 LMSRFNAFKRTNT---ILHHLRMSKHTDAAEEVLLEKKGCTGVITLNRPK-FLNALTLNM 64 ++SRF+AF+ + I + S + KG V+ +N P +N L+ + Sbjct: 9 ILSRFSAFRILRSRGYICRNFTGSSALLTRTHINYGVKGDVAVVRINSPNSKVNTLSKEL 68 Query: 65 IRQIYPQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRVISEAEKAKQKIAPVFFREEYML 124 + + + + ++ + F AG DI +++ A K Q++ +E + Sbjct: 69 HSEFSEVMNEIWASDQIRSAVLISSKPGCFIAGADINMLA-ACKTLQEVTQ-LSQEAQRI 126 Query: 125 NNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEK--CLFAMPETAIGLFPDVGGGY 182 + KP VA I+G +GGG+ +++ Q+R+AT+ + PE +G P GG Sbjct: 127 VEKLEKSTKPIVAAINGSCLGGGLEVAISCQYRIATKDRKTVLGTPEVLLGALPGAGGTQ 186 Query: 183 FLPRLQG-KLGYFLALTGFRLKGRDVYRAGIATHFVDS 219 LP++ G + LTG ++ + G+ V+ Sbjct: 187 RLPKMVGVPAALDMMLTGRSIRADRAKKMGLVDQLVEP 224 >4FZW-A nrPDB Length = 258 Score = 201 bits (511), Expect = 5e-52, Method: Composition-based stats. Identities = 60/261 (22%), Positives = 108/261 (41%), Gaps = 13/261 (4%) Query: 37 EVLLEKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCA 96 E+++ ++ ++TLNRP NAL ++ Q+ +L+ D + +I G + F A Sbjct: 6 ELIVSRQQRVLLLTLNRPAARNALNNALLMQLVNELEAAATDTSISVCVITG-NARFFAA 64 Query: 97 GGDIRVISEAEKAKQKIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQF 156 G D+ ++E + +A L + + KP +A ++G +G G L++ Sbjct: 65 GADLNEMAE-----KDLAATLNDTRPQLWARLQAFNKPLIAAVNGYALGAGCELALLCDV 119 Query: 157 RVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGK-LGYFLALTGFRLKGRDVYRAGIATH 215 VA E F +PE +G+ P GG L R GK L + L+G + + +AG+ + Sbjct: 120 VVAGENARFGLPEITLGIMPGAGGTQRLIRSVGKSLASKMVLSGESITAQQAQQAGLVSD 179 Query: 216 FVDSE---KLAMLEEDLLALKSPSKENIASVLENYHTESKIDRDKSFILEEHMDKINSCF 272 S+ + A+ +A SP A E + + +E Sbjct: 180 VFPSDLTLEYALQLASKMARHSPLALQAAKQALRQSQEVALQAG---LAQERQLFTLLAA 236 Query: 273 SANTVEEIIENLQQDGSSFAL 293 + + E I LQ+ F Sbjct: 237 TEDRHEGISAFLQKRTPDFKG 257 >3MOY-A nrPDB Length = 263 Score = 201 bits (510), Expect = 6e-52, Method: Composition-based stats. Identities = 57/248 (22%), Positives = 100/248 (40%), Gaps = 8/248 (3%) Query: 45 CTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRVIS 104 G+I L+RP LNAL + ++ + ++ D E I++ G+ +AF AG DI + Sbjct: 19 GVGLIRLDRPDALNALNQTLEAEVLDAARDFDADLEIGAIVVTGS-ERAFAAGADIAEMV 77 Query: 105 EAEKAKQKIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCL 164 + + + +++ +KP VA + G +GGG L++ +A + Sbjct: 78 TLTPHQARERNLLSGW-----DSLTQVRKPIVAAVAGYALGGGCELAMLCDLVIAADTAR 132 Query: 165 FAMPETAIGLFPDVGGGYFLPRLQGKL-GYFLALTGFRLKGRDVYRAGIATHFVDSEKLA 223 F PE +G+ P +GG L R GK L LTG L + R G+ + V + L Sbjct: 133 FGQPEITLGILPGLGGTQRLTRAVGKAKAMDLCLTGRSLTAEEAERVGLVSRIVPAADL- 191 Query: 224 MLEEDLLALKSPSKENIASVLENYHTESKIDRDKSFILEEHMDKINSCFSANTVEEIIEN 283 + E +A + A +R S + D + F + E + Sbjct: 192 LDEALAVAQRIARMSRPAGRAVKDAINEAFERPLSAGMRYERDAFYAMFDTHDQTEGMTA 251 Query: 284 LQQDGSSF 291 + + Sbjct: 252 FLEKRTPE 259 >5JBW-A nrPDB Length = 260 Score = 195 bits (495), Expect = 3e-50, Method: Composition-based stats. Identities = 51/236 (21%), Positives = 91/236 (38%), Gaps = 5/236 (2%) Query: 36 EEVLLEKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFC 95 E ++ +G + T++ NA++ M++++ + + + ++I GAG KAFC Sbjct: 4 PEFKVDARGPIEIWTIDGESRRNAISRAMLKELGELVTRVSSSRDVRAVVITGAGDKAFC 63 Query: 96 AGGDIRVISEAEKAKQKIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQ 155 AG D++ + + F A+ ++A I+G +GGG L++ Sbjct: 64 AGADLKERATMA---EDEVRAFLDGLRRTFRAIEKSDCVFIAAINGAALGGGTELALACD 120 Query: 156 FRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGK-LGYFLALTGFRLKGRDVYRAGIAT 214 RVA + E +G+ P GG L RL G L LT R+ + + G+A Sbjct: 121 LRVAAPAAELGLTEVKLGIIPGGGGTQRLARLVGPGRAKDLILTARRINAAEAFSVGLAN 180 Query: 215 HFVDSEKLAMLEEDLLALKSPSKENIASVLENYHTESKIDRDKSFILEEHMDKINS 270 L + LA IA + + + L + K Sbjct: 181 RLAPEGHLLAVAYG-LAESVVENAPIAVATAKHAIDEGTGLELDDALALELRKYEE 235 >6OJM-A nrPDB Length = 286 Score = 191 bits (484), Expect = 5e-49, Method: Composition-based stats. Identities = 45/269 (16%), Positives = 93/269 (34%), Gaps = 13/269 (4%) Query: 36 EEVLLEKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGA------ 89 E++ +K I NRP+ NA ++Y +DP ++++ G Sbjct: 19 EDITYKKCNGVARIAFNRPEIRNAFRPKTTSELYDAFYDAYEDPSIGVVLLSGEGPSPKD 78 Query: 90 GGKAFCAGGDIRVISEAEKAKQKIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVG 149 GG AFC+GGD + + E + + K +A++ G +GGG Sbjct: 79 GGWAFCSGGDQKARGHQGYVGEDGRHRLNILE--VQRLIRFMPKVVIAVVPGWAVGGGHS 136 Query: 150 LSVHGQFRVAT-EKCLFAMPETAIGLFPDVGGGYFLPRLQGK-LGYFLALTGFRLKGRDV 207 L V +A+ E +F + + F G +L ++ G+ + G ++ Sbjct: 137 LHVVCDLTLASKEHAIFKQTDADVTSFDGGYGSAYLAKMVGQKKAREIFFLGRNYSAQEA 196 Query: 208 YRAGIATHFVDSEKLAMLEEDLLALKSPSKENIASVLENYHTESKIDRDKSFILEEHMDK 267 + G+ V +L + +L+ + + + Sbjct: 197 FEMGMVNKVVPHAELEDTAYEWAQEILAKSPTSIRMLKFAMNLTDDGMVGQQVFAGEATR 256 Query: 268 INSCFSANTVEEIIEN-LQQDGSSFALEQ 295 + + + +E L++ F +Q Sbjct: 257 L--AYMTDEAKEGRNAFLEKRKPDFGEDQ 283 >4JWV-A nrPDB Length = 278 Score = 190 bits (482), Expect = 1e-48, Method: Composition-based stats. Identities = 58/215 (26%), Positives = 98/215 (45%), Gaps = 11/215 (5%) Query: 31 HTDAAEEVLLEKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAG 90 + + ++ +G + LNRP+ LNA+T M + + + + + +++ G Sbjct: 19 YFQSMADIDFRIEGHVAHVRLNRPQGLNAITQEMDDLLLDAWTEVNANSDIWAVVLSAEG 78 Query: 91 GKAFCAGGDIRVISEAEKAKQKIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGL 150 KAFC G D+ A++K + + +C+KP VA + G +GGG L Sbjct: 79 EKAFCIGADVS-----GGAERKTRMALGGGLTGIGGPLVTCKKPMVAAVQGFCVGGGFEL 133 Query: 151 SVHGQFRVATEKCLFAMPETAIGLFPDVGGGYF-LPRLQGKLGYFLALTGFRLKGRDVYR 209 ++ VA + F +PET +G+ + G + + +L + L LTG R+K + Sbjct: 134 AMCADIIVAADTAQFGLPETKVGIIGECGVVHRAMRQLPYHIALQLILTGERIKADEARH 193 Query: 210 AGIATHFVDSEKLAMLEEDLLALKSPSKENIASVL 244 G+ V A LEE AL+ SK N AS L Sbjct: 194 YGLVNEVVP---FAELEEA--ALRWASKLNAASPL 223 >4JCS-A nrPDB Length = 286 Score = 184 bits (468), Expect = 4e-47, Method: Composition-based stats. Identities = 52/261 (19%), Positives = 97/261 (37%), Gaps = 3/261 (1%) Query: 31 HTDAAEEVLLEKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAG 90 + + + + E G I +NR N + + L++ D + ++++ Sbjct: 19 YFQSMDTLDFEVVNNVGWIRMNRAAKHNPFDAELRADLMTVLERVRDDADIRVLVLTSHP 78 Query: 91 GKAFCAGGDIRVISEAEKAKQKIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGL 150 G +FCAGG++ V+ + + + + + + +P +A + G G G L Sbjct: 79 G-SFCAGGNLHVLRDNLDSGPAYWQQRIKTGLRFIHDMLNLGRPVIAAVDGPAFGAGFAL 137 Query: 151 SVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQG-KLGYFLALTGFRLKGRDVYR 209 S+ +A+ + F+M +GL PD+G Y LPR G + L + L + +R Sbjct: 138 SLTADIVLASPRARFSMAYLRLGLVPDLGALYLLPRAVGLQRAKELMFSTRELDAEEAHR 197 Query: 210 AGIATHFVDSEKLAMLEEDLLALKSPSKENIASVLENYHTESKIDRDKSFILEEHMDKIN 269 G+ +SE L +A A L +D D+ + Sbjct: 198 LGLVMEVHESEALEQ-RAREIAESLVQAAPTALALTKAALNVSLDSDEQTMFSLEAASQA 256 Query: 270 SCFSANTVEEIIENLQQDGSS 290 + FS IE L Sbjct: 257 AAFSTKEPRAAIEALLSKQPP 277 >4IZC-A nrPDB Length = 275 Score = 184 bits (467), Expect = 6e-47, Method: Composition-based stats. Identities = 55/224 (24%), Positives = 93/224 (41%), Gaps = 7/224 (3%) Query: 42 KKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCAGGDIR 101 + V+TLNRP NAL + I ++ + +++ GAG FCAG D+ Sbjct: 17 RDNGVCVVTLNRPDKRNALDVATIEELVTFFSTAHR-KGVRAVVLTGAG-DHFCAGLDLV 74 Query: 102 VISEAEKAKQKIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATE 161 +A+++ V R N + P +A + G +GGG+ L+ RV + Sbjct: 75 EHWKADRSADDFMHVCLRWHEAFNK-MEYGGVPIIAALRGAVVGGGLALASAAHLRVMDQ 133 Query: 162 KCLFAMPETAIGLFPDVGGGYFLPRLQGKLGY-FLALTGFRLKGRDVYRAGIATHFVDSE 220 FA+PE G+F G + + GK + LTG +G++ G+A + + Sbjct: 134 STYFALPEGQRGIFTGGGATIRVSDMIGKYRMIDMILTGRVYQGQEAADLGLAQYITEGS 193 Query: 221 KL--AMLEEDLLALKSP-SKENIASVLENYHTESKIDRDKSFIL 261 AM D +A P + I S + + S +D + Sbjct: 194 SFDKAMELADKIASNLPLTNFAICSAISHMQNMSGLDAAYAEAF 237 >2VSU-C nrPDB Length = 275 Score = 184 bits (466), Expect = 7e-47, Method: Composition-based stats. Identities = 47/223 (21%), Positives = 88/223 (39%), Gaps = 4/223 (1%) Query: 28 MSKHTDAAEEVLLEKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIK 87 MS + + V +E + + LNRP+ NA++ + R++ L+ EQDP ++++ Sbjct: 1 MSTYEGRWKTVKVEIEDGIAFVILNRPEKRNAMSPTLNREMIDVLETLEQDPAAGVLVLT 60 Query: 88 GAGGKAFCAGGDIRVISEAEKAKQKIAPVFFREEYMLNNA--VGSCQKPYVALIHGITMG 145 GAG A+ AG D++ A +I R E + KP +A+++G G Sbjct: 61 GAGE-AWTAGMDLKEYFREVDAGPEILQEKIRREASQWQWKLLRMYAKPTIAMVNGWCFG 119 Query: 146 GGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGKL-GYFLALTGFRLKG 204 GG V + ++ F + E G+ P + G + +TG G Sbjct: 120 GGFAPLVACDLAICADEATFGLSEINWGIPPGNLVSKAMADTVGHRQSLYYIMTGKTFGG 179 Query: 205 RDVYRAGIATHFVDSEKLAMLEEDLLALKSPSKENIASVLENY 247 + G+ V +L + +L + ++ Sbjct: 180 QKAAEMGLVNESVPLAQLREVTIELARNLLEKNPVVLRAAKHG 222 >3T8B-A nrPDB Length = 334 Score = 182 bits (461), Expect = 3e-46, Method: Composition-based stats. Identities = 52/259 (20%), Positives = 92/259 (35%), Gaps = 33/259 (12%) Query: 7 WRLMSRFNAFKRTNTILHHLRMSKHTDAAEEVLLEKKGCTGVITLNRPKFLNALTLNMIR 66 WRL+ + F I +H +H D A T + NRP+ NA + + Sbjct: 45 WRLV---DGFDDLTDITYH----RHVDDA----------TVRVAFNRPEVRNAFRPHTVD 87 Query: 67 QIYPQLKKWEQDPETFLIIIKG------AGGKAFCAGGDIR-------VISEAEKAKQ-K 112 ++Y L P+ ++++ G GG AFC+GGD R + + A Sbjct: 88 ELYRVLDHARMSPDVGVVLLTGNGPSPKDGGWAFCSGGDQRIRGRSGYQYASGDTADTVD 147 Query: 113 IAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVAT-EKCLFAMPETA 171 +A + + K + L++G GGG L V +A+ E F + Sbjct: 148 VARAGRLHILEVQRLIRFMPKVVICLVNGWAAGGGHSLHVVCDLTLASREYARFKQTDAD 207 Query: 172 IGLFPDVGGGYFLPRLQGKL-GYFLALTGFRLKGRDVYRAGIATHFVDSEKLAMLEEDLL 230 +G F G +L R G+ + G +++ G + +L + Sbjct: 208 VGSFDGGYGSAYLARQVGQKFAREIFFLGRTYTAEQMHQMGAVNAVAEHAELETVGLQWA 267 Query: 231 ALKSPSKENIASVLENYHT 249 A + +L+ Sbjct: 268 AEINAKSPQAQRMLKFAFN 286 >4ZU2-A nrPDB Length = 272 Score = 179 bits (453), Expect = 3e-45, Method: Composition-based stats. Identities = 66/241 (27%), Positives = 108/241 (44%), Gaps = 7/241 (2%) Query: 36 EEVLLEKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFC 95 E +LLE ITLNRP+ NA++L M+ ++ L D ++++GA G FC Sbjct: 7 ETLLLEPIEGVLRITLNRPQSRNAMSLAMVGELRAVLAAVRDDRSVRALVLRGADG-HFC 65 Query: 96 AGGDIRVISEAEKAKQKIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQ 155 AGGDI+ ++ A A + R L + + VAL+ G +GGG GL+ Sbjct: 66 AGGDIKDMAGARAAGAEAYRTLNRAFGSLLEEAQAAPQLLVALVEGAVLGGGFGLACVSD 125 Query: 156 FRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGKLGYFLALTGFRLKGRDVYRAGIATH 215 +A F +PET++G+ P + + R+ LALT R GR+ R G+ H Sbjct: 126 VAIAAADAQFGLPETSLGILPAQIAPFVVRRIGLTQARRLALTAARFDGREALRLGLV-H 184 Query: 216 FVDSEKLAM---LEEDLLALK--SPSKENIASVLENYHTESKIDRDKSFILEEHMDKINS 270 F +++ A+ LEE L L+ +P+ L ++ + + + Sbjct: 185 FCEADADALEQRLEETLEQLRRCAPNANAATKALLLASESGELGALLDDAARQFAEAVGG 244 Query: 271 C 271 Sbjct: 245 A 245 >5KJP-A nrPDB Length = 265 Score = 171 bits (434), Expect = 4e-43, Method: Composition-based stats. Identities = 70/257 (27%), Positives = 110/257 (42%), Gaps = 16/257 (6%) Query: 28 MSKHTDAA---EEVLLEKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLI 84 MS +DAA EVL+E++ +IT+NRPK NA+ + R + + + + D + Sbjct: 4 MSSESDAANTEPEVLVEQRDRILIITINRPKAKNAVNAAVSRGLADAMDQLDGDAGLSVA 63 Query: 85 IIKGAGGKAFCAGGDIRVISEAEKAKQKIAPVFFREEYMLNNAVGSCQKPYVALIHGITM 144 I+ G GG +FCAG D++ + E + + F E KP +A + G + Sbjct: 64 ILTGGGG-SFCAGMDLKAFARGENVVVEGRGLGFTERPP--------TKPLIAAVEGYAL 114 Query: 145 GGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLP-RLQGKLGYFLALTGFRLK 203 GG L++ VA F +PE GL GG LP R+ + LALTG L Sbjct: 115 AGGTELALAADLIVAARDSAFGIPEVKRGLVAGGGGLLRLPERIPYAIAMELALTGDNLP 174 Query: 204 GRDVYRAGIATHFVDSEKLAMLEEDL-LALKSPSKENIASVLENYHTESKIDRDKSFILE 262 + G+ V +E L+ + LA K + +A V + Sbjct: 175 AERAHELGLVN--VLAEPGTALDAAIALAEKITANGPLAVVATKRIITESRGWSPDTMFA 232 Query: 263 EHMDKINSCFSANTVEE 279 E M + F++N +E Sbjct: 233 EQMKILVPVFTSNDAKE 249 >5VE2-A nrPDB Length = 275 Score = 171 bits (433), Expect = 5e-43, Method: Composition-based stats. Identities = 50/219 (22%), Positives = 90/219 (41%), Gaps = 15/219 (6%) Query: 35 AEEVLLEKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAF 94 ++ + + +T+NRP+ NAL + + +L++ D + +++ A G F Sbjct: 24 SKSLNVSLNNRVLSLTINRPELKNALNRELYAALADELERSNHDDQIRAVLLT-ANGDTF 82 Query: 95 CAGGDIRVISEAEKAKQKIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHG 154 AG D+ ++ P A+ C+ P V ++G +G G+ + +H Sbjct: 83 TAGNDLDDF--INPVEESGTP----SVIRFLKAISECETPIVVAVNGPAIGVGLTMLLHC 136 Query: 155 QFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGK-LGYFLALTGFRLKGRDVYRAGIA 213 A++ F P T +GL P+ LP G+ L L G L R+ AG+ Sbjct: 137 DMVYASKSARFRAPFTHVGLVPEAASSLLLPLAVGQAWANDLMLAGRILDAREALSAGLV 196 Query: 214 THFVDSEKLAMLEEDLLALKSPSKENIASVLENYHTESK 252 T + + L +A E +AS+ N +SK Sbjct: 197 TRVFEDDVL-------VAESLKIAEQVASLAPNSVKQSK 228 >3I47-A nrPDB Length = 268 Score = 171 bits (433), Expect = 5e-43, Method: Composition-based stats. Identities = 48/223 (21%), Positives = 87/223 (39%), Gaps = 4/223 (1%) Query: 37 EVLLEKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCA 96 ++L E + G++T+NR NA ++ ++ +L D +I++K A GK F A Sbjct: 5 DLLYEIQDKVGLLTMNRISKHNAFDNQLLTEMRIRLDSAINDTNVRVIVLK-ANGKHFSA 63 Query: 97 GGDIRVISEAEKAKQKIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQF 156 G D+ + ++ L ++ KP +A++ G GGG GL+ Sbjct: 64 GADLTWMQSMANFTEEENLEDSLVLGNLMYSISQSPKPTIAMVQGAAFGGGAGLAAACDI 123 Query: 157 RVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGKLGYFLALTGFRLKGRDVYRAGIATHF 216 +A+ F E +GL P V Y + + + L ++ Y + H Sbjct: 124 AIASTSARFCFSEVKLGLIPAVISPYVVRAIGERAAKMLFMSAEVFDATRAYSLNLVQHC 183 Query: 217 VDSEKLAMLE---EDLLALKSPSKENIASVLENYHTESKIDRD 256 V + L ++ +P + L Y KID + Sbjct: 184 VPDDTLLEFTLKYASQISNNAPEAVKNSKQLAQYVANKKIDEE 226 >1EF9-A nrPDB Length = 261 Score = 170 bits (430), Expect = 1e-42, Method: Composition-based stats. Identities = 42/193 (21%), Positives = 74/193 (38%), Gaps = 7/193 (3%) Query: 36 EEVLLEKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKG-AGGKAF 94 + V + VI N + LNAL+ I + L + PE II++ +G K F Sbjct: 4 QYVNVVTINKVAVIEFNYGRKLNALSKVFIDDLMQALSDLNR-PEIRCIILRAPSGSKVF 62 Query: 95 CAGGDIRVISEAEKAKQKIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHG 154 AG DI + + + + + KP ++++ G GG + + Sbjct: 63 SAGHDIHELPSGGRDP----LSYDDPLRQITRMIQKFPKPIISMVEGSVWGGAFEMIMSS 118 Query: 155 QFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQG-KLGYFLALTGFRLKGRDVYRAGIA 213 +A F+M +G+ ++ G + L R G + L T + + GI Sbjct: 119 DLIIAASTSTFSMTPVNLGVPYNLVGIHNLTRDAGFHIVKELIFTASPITAQRALAVGIL 178 Query: 214 THFVDSEKLAMLE 226 H V+ E+L Sbjct: 179 NHVVEVEELEDFT 191 >2PPY-A nrPDB Length = 265 Score = 169 bits (429), Expect = 1e-42, Method: Composition-based stats. Identities = 45/254 (17%), Positives = 94/254 (37%), Gaps = 7/254 (2%) Query: 28 MSKHTDAAEEVLLEKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIK 87 M+ + + + K+ I L N+ L ++ + DP+ ++I+ Sbjct: 1 MTAVETKKQYLTVFKEDGIAEIHL-HINKSNSYDLEFYKEFNAAIDDIRFDPDIKVVIVM 59 Query: 88 GAGGKAFCAGGDIRVISEAEKAKQKIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGG 147 K F AG DI + A+ + K F E + + + + Y+A + G T+GGG Sbjct: 60 SDVPKFFSAGADINFLRSADP-RFKTQFCLFCNETL--DKIARSPQVYIACLEGHTVGGG 116 Query: 148 VGLSVHGQFRVATEKC-LFAMPETAIGLFPDVGGGYFLPRLQG-KLGYFLALTGFRLKGR 205 + +++ R ++ +PE ++G+ GG L RL G + +TG + + Sbjct: 117 LEMALACDLRFMGDEAGKIGLPEVSLGVLAGTGGTQRLARLIGYSRALDMNITGETITPQ 176 Query: 206 DVYRAGIATHFVDSEKLAMLEEDLLALKSPSKENIASVLENYHTESKIDRDKSFILEEHM 265 + G+ + + A K + A + + + + Sbjct: 177 EALEIGLVNRVFPQAETRERTREY-ARKLANSATYAVSNIKLAIMNGKEMPLNVAIRYEG 235 Query: 266 DKINSCFSANTVEE 279 + N F + +E Sbjct: 236 ELQNLLFRSEDAKE 249 >1NZY-B nrPDB Length = 269 Score = 169 bits (428), Expect = 2e-42, Method: Composition-based stats. Identities = 46/210 (21%), Positives = 90/210 (42%), Gaps = 12/210 (5%) Query: 36 EEVLLEKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFC 95 E + + IT+ P+ NAL++ ++++ L + E+D ++I GA AFC Sbjct: 3 EAIGHRVEDGVAEITIKLPRHRNALSVKAMQEVTDALNRAEEDDSVGAVMITGA-EDAFC 61 Query: 96 AGGDIRVIS-----EAEKAKQKIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGL 150 AG +R I + +IA +++ + M++ + ++P +A I+G+ GGG+G+ Sbjct: 62 AGFYLREIPLDKGVAGVRDHFRIAALWWHQ--MIHKIIR-VKRPVLAAINGVAAGGGLGI 118 Query: 151 SVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQG-KLGYFLALTGFRLKGRDVYR 209 S+ + + F IG+ D Y L R+ G + L LT L + Sbjct: 119 SLASDMAICADSAKFVCAWHTIGIGNDTATSYSLARIVGMRRAMELMLTDRTLYPEEAKD 178 Query: 210 AGIATHFVDSEKLAMLEEDLLALKSPSKEN 239 G+ + ++ E + + Sbjct: 179 WGLVSRVYPKDEFR--EVAWKVARELAAAP 206 >3HIN-A nrPDB Length = 275 Score = 169 bits (427), Expect = 2e-42, Method: Composition-based stats. Identities = 49/214 (22%), Positives = 90/214 (42%), Gaps = 11/214 (5%) Query: 37 EVLLEKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCA 96 ++++ G I LNRPK NAL ++ + L + ++I G G F A Sbjct: 17 TLVVDTVGPVLTIGLNRPKKRNALNDGLMAALKDCLTDIP--DQIRAVVIHGIG-DHFSA 73 Query: 97 GGDIRVISEAEKAKQKIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQF 156 G D+ + E + + + + + + + + C+ P +A + G +GGG+ L+ Sbjct: 74 GLDLSELRERDATEGLVHSQTW---HRVFDKIQYCRVPVIAALKGAVIGGGLELACAAHI 130 Query: 157 RVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGKLGY-FLALTGFRLKGRDVYRAGIATH 215 RVA +A+PE + G+F GG LPRL G + LTG + G + + Sbjct: 131 RVAEASAYYALPEGSRGIFVGGGGSVRLPRLIGVARMADMMLTGRVYSAAEGVVHGFSQY 190 Query: 216 FVDS----EKLAMLEEDLLALKSPSKENIASVLE 245 +++ +K L + + + L Sbjct: 191 LIENGSAYDKALELGNRVAQNAPLTNFAVLQALP 224 >3OME-A nrPDB Length = 282 Score = 167 bits (422), Expect = 8e-42, Method: Composition-based stats. Identities = 52/225 (23%), Positives = 90/225 (40%), Gaps = 25/225 (11%) Query: 37 EVLLEKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCA 96 + ITLNRP+ NA ++ ++ + +D E +II++ A GK F A Sbjct: 24 YIDYGVADSIATITLNRPEAANAQNPELLDELDAAWTRAAEDNEVKVIILR-ANGKHFSA 82 Query: 97 GGDIRVISEAEKAKQKIAPVFFREEYM-----LNNAVGSCQKPYVALIHGITMGGGVGLS 151 G D+R + +KI+ F + + KP +A + G + GG+ L Sbjct: 83 GHDLRG---GGEVPEKISLEFIIQHEARRYLDYTLRWRNVPKPSIAAVQGRCISGGLLLC 139 Query: 152 VHGQFRVATEKCLFAMPETAIGLFPDV---GGGYFL-PRLQGKLGYFLALTGFRLKGRDV 207 +A++ LF+ P +G+ V G + L PR + TG L + Sbjct: 140 WPCDLILASDDALFSDPVALMGIG-GVEYHGHTWELGPR----KAKEILFTGRALTAEEA 194 Query: 208 YRAGIATHFVDSEKLAMLEEDLLALKSPSKENIASVLENYHTESK 252 R G+ V ++L +L E IA++ ++K Sbjct: 195 ERTGMVNRVVARDELDAQTREL-------AEQIATMPPFALRQAK 232 >6IUM-B nrPDB Length = 701 Score = 166 bits (420), Expect = 1e-41, Method: Composition-based stats. Identities = 56/227 (24%), Positives = 98/227 (43%), Gaps = 13/227 (5%) Query: 40 LEKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCAGGD 99 + + VITL+ P +N L + I + + D I+I GAG KAF G D Sbjct: 5 YQVQDGVAVITLDNPP-VNGLGHSTRLGIVEGMTRALDDAAVKAIVITGAG-KAFSGGAD 62 Query: 100 IRVISEAEKAKQKIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVA 159 IR + KA Q+ + + + KP VA +H + MGGG+ L++ +RVA Sbjct: 63 IREFN-TPKAMQEPTL------HSVIRVLEGSSKPVVAAVHSVAMGGGLELALGCNYRVA 115 Query: 160 TEKCLFAMPETAIGLFPDVGGGYFLPRLQG-KLGYFLALTGFRLKGRDVYRAGIATHFVD 218 ++ A+PE +GL P GG LPR+ G + + ++G + + VD Sbjct: 116 SKGAQIALPEVKLGLLPGAGGTQRLPRVIGLEAAANMIVSGTPVLSEKFAGTKLFDEIVD 175 Query: 219 SEKLAM---LEEDLLALKSPSKENIASVLENYHTESKIDRDKSFILE 262 + L +++ A P + + + + E + ++ + Sbjct: 176 GDVLPAAVKFAQNVGAATGPHPKVRDLKVRHENPEGYLGFARNTVAA 222 >4FZW-C nrPDB Length = 274 Score = 164 bits (415), Expect = 6e-41, Method: Composition-based stats. Identities = 67/262 (25%), Positives = 107/262 (40%), Gaps = 5/262 (1%) Query: 36 EEVLLEKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFC 95 E +L + +TLNRP+ LN+ M Q+ LK+ E+D +++ GAG + FC Sbjct: 15 EFILSHVEKGVMTLTLNRPERLNSFNDEMHAQLAECLKQVERDDTIRCLLLTGAG-RGFC 73 Query: 96 AGGDIRVISEAEKAKQ-KIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHG 154 AG D+ + + R L + KP + ++G+ G G L++ G Sbjct: 74 AGQDLNDRNVDPTGPAPDLGMSVERFYNPLVRRLAKLPKPVICAVNGVAAGAGATLALGG 133 Query: 155 QFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGKL-GYFLALTGFRLKGRDVYRAGIA 213 +A F M + +GL PD GG + LPR+ G+ LAL G +L + G+ Sbjct: 134 DIVIAARSAKFVMAFSKLGLIPDCGGTWLLPRVAGRARAMGLALLGNQLSAEQAHEWGMI 193 Query: 214 THFVDSEKLAMLEEDLLALKSPSKENIASVLENYHTESKIDRDKSFILEEHMD-KINSCF 272 VD E LA LA ++ L S L+ D + + Sbjct: 194 WQVVDDETLAD-TAQQLARHLATQPTFGLGLIKQAINSAETNTLDTQLDLERDYQRLAGR 252 Query: 273 SANTVEEIIENLQQDGSSFALE 294 SA+ E + L + F + Sbjct: 253 SADYREGVSAFLAKRSPQFTGK 274 >2D3T-A nrPDB Length = 715 Score = 162 bits (411), Expect = 2e-40, Method: Composition-based stats. Identities = 50/260 (19%), Positives = 91/260 (35%), Gaps = 14/260 (5%) Query: 55 KFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRVISEAEKAKQKIA 114 + +N + ++ + + D +I+ +G F G DI E K Sbjct: 27 ESVNKFNRLTLNELRQAVDAIKADASVKGVIVS-SGKDVFIVGADITEFVENFKLPDAEL 85 Query: 115 PVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGL 174 E + + P VA I+GI +GGG+ + + FRV + +PE +G+ Sbjct: 86 IAGNLEANKIFSDFEDLNVPTVAAINGIALGGGLEMCLAADFRVMADSAKIGLPEVKLGI 145 Query: 175 FPDVGGGYFLPRLQGK-LGYFLALTGFRLKGRDVYRAGIATHFVDSEKLAMLEEDLLALK 233 +P GG LPRL G +G + D + V ++KL AL Sbjct: 146 YPGFGGTVRLPRLIGVDNAVEWIASGKENRAEDALKVSAVDAVVTADKLGA-----AALD 200 Query: 234 SPSKENIASVLENYHTESKIDRDKSFILEEHMDKINSCFSANTVEEIIENLQQDGSSFAL 293 + + + K+++ K ++ I + T + + + Sbjct: 201 LIKRAISGELDYKAKRQPKLEKLK-------LNAIEQMMAFETAKGFVAGQAGPNYPAPV 253 Query: 294 EQLKVINKMSPTSLKITLRQ 313 E +K I K + L Sbjct: 254 EAIKTIQKAANFGRDKALEV 273 >2WTB-A nrPDB Length = 725 Score = 161 bits (408), Expect = 4e-40, Method: Composition-based stats. Identities = 47/188 (25%), Positives = 83/188 (44%), Gaps = 3/188 (1%) Query: 44 GCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRVI 103 VITL P +N+L+ +++ + ++ + I+I GA G+ F G DI Sbjct: 16 DGVAVITLINPP-VNSLSFDVLYNLKSNYEEALSRNDVKAIVITGAKGR-FSGGFDISGF 73 Query: 104 SEAEKAKQKIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKC 163 E +K K + ++ + + + +KP VA I G+ +GGG+ L++ R++ Sbjct: 74 GEMQKGNVKEPKAGYISIDIITDLLEAARKPSVAAIDGLALGGGLELAMACHARISAPAA 133 Query: 164 LFAMPETAIGLFPDVGGGYFLPRLQG-KLGYFLALTGFRLKGRDVYRAGIATHFVDSEKL 222 +PE +G+ P GG LPRL G + LT +K + + G+ V +L Sbjct: 134 QLGLPELQLGVIPGFGGTQRLPRLVGLTKALEMILTSKPVKAEEGHSLGLIDAVVPPAEL 193 Query: 223 AMLEEDLL 230 Sbjct: 194 VTTARRWA 201 >4JFC-A nrPDB Length = 281 Score = 157 bits (397), Expect = 6e-39, Method: Composition-based stats. Identities = 55/233 (23%), Positives = 101/233 (43%), Gaps = 9/233 (3%) Query: 35 AEEVLLEKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAF 94 A + +G T ++TL+ P+F NAL + L E +PE ++I G G F Sbjct: 24 AGAIKSTSEGQTLILTLSNPEFRNALGPEIYAAGIEALNAAENNPEIRSVVITGEGA-VF 82 Query: 95 CAGGDIRVISEAEKAKQKIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHG 154 CAGG+++ + + ++ + +++ + KP +A + G G G L++ Sbjct: 83 CAGGNLQRLQANRREAPEVQAQSIEGLHNWIDSIRTYPKPVIAAVEGAAAGAGFSLALAC 142 Query: 155 QFRVATEKCLFAMPETAIGLFPDVGGGYFLPR-LQGKLGYFLALTGFRLKGRDVYRAGIA 213 F VA +F M + +GL PD GG + L R L L L + G R+ + ++ G+ Sbjct: 143 DFVVAASNAVFVMSYSTVGLSPDGGGSWSLARSLPRALASELLMGGERISAQRLHDLGLV 202 Query: 214 THFVDS-EKLAMLEEDLLALKSPSKENIASVLENYHTESKIDRDKSFILEEHM 265 + + L+ AL+ + N + + I+ S L + + Sbjct: 203 NKVASAGDALSE------ALRMAGQLNARAPNALASIKELINEASSNTLSQQL 249 >3ZWA-A nrPDB Length = 742 Score = 157 bits (397), Expect = 7e-39, Method: Composition-based stats. Identities = 61/249 (24%), Positives = 98/249 (39%), Gaps = 16/249 (6%) Query: 47 GVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRVISEA 106 +I L P +NA++ +IR++ L+K D I+I GA G FCAG DI S Sbjct: 32 AMIRLCNPP-VNAVSPTVIREVRNGLQKAGSDHTVKAIVICGANGN-FCAGADIHGFSAF 89 Query: 107 EKAKQKIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFA 166 L + + QKP +A I G+ +GGG+ L++ +R+A K Sbjct: 90 TPG---------LALGSLVDEIQRYQKPVLAAIQGVALGGGLELALGCHYRIANAKARVG 140 Query: 167 MPETAIGLFPDVGGGYFLPRLQG-KLGYFLALTGFRLKGRDVYRAGIATHFVDSEKLAML 225 +PE +G+ P G LPR+ G + L +G L + R GI V S+ + Sbjct: 141 LPEVTLGILPGARGTQLLPRVVGVPVALDLITSGKYLSADEALRLGILDAVVKSDPV--- 197 Query: 226 EEDLLALKSPSKENIASVLENYHTESKIDRDKSFILEEHMDKINSCFSANTVEEIIENLQ 285 EE + + + I + + + E + K+ + E Sbjct: 198 EEAIKFAQKIIDKPIEPRRIFNKPVPSLP-NMDSVFAEAIAKVRKQYPGVLAPETCVRSI 256 Query: 286 QDGSSFALE 294 Q E Sbjct: 257 QASVKHPYE 265 >2A81-A nrPDB Length = 250 Score = 151 bits (382), Expect = 4e-37, Method: Composition-based stats. Identities = 42/234 (17%), Positives = 83/234 (35%), Gaps = 7/234 (2%) Query: 41 EKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCAGGDI 100 E VITL+ P N + + + L + D +++ G ++F AGGD Sbjct: 5 ENSDEVRVITLDHPNKHNPFSRTLETSVKDALARANADDSVRAVVVYGGAERSFSAGGDF 64 Query: 101 RVISEAEKAKQKIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVAT 160 + + +++ + L AV + KP +A + G +G G ++ R+ Sbjct: 65 NEVKQLSRSEDIE--EWIDRVIDLYQAVLNVNKPTIAAVDGYAIGMGFQFALMFDQRLMA 122 Query: 161 EKCLFAMPETAIGLFPDVGGGYFLPRLQGKLGYFLALTGFRLKGRDVYRAGIATHFVDSE 220 F MPE G+ VG + L + V+S Sbjct: 123 STANFVMPELKHGIGCSVGAAILGFTHGFSTMQEIIYQCQSLDAPRCVDYRLVNQVVESS 182 Query: 221 KLAMLEEDLLALKSPSKENIASVLENYHTESKIDRDKSFILEEHMDKINSCFSA 274 A+L+ + + ++ + T+ +++ +LE+ D + A Sbjct: 183 --ALLDAAITQAHVMASYPASAFIN---TKRAVNKPFIHLLEQTRDASKAVHKA 231 >4JSB-A nrPDB Length = 296 Score = 148 bits (374), Expect = 3e-36, Method: Composition-based stats. Identities = 52/242 (21%), Positives = 90/242 (37%), Gaps = 24/242 (9%) Query: 29 SKHTDAAEEVLLEKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQD--PETFLIII 86 + AA + L G ITL+RP NA+T M + +L + +++I Sbjct: 29 TAEELAAAGLTLTIDGEVARITLSRPHRRNAMTGRM----WTELARIGHTLPQAVRIVVI 84 Query: 87 KGAGGKAFCAGGDIRVISEAEKAKQKIAPVFFREEY-----MLNNAVGSCQK-------- 133 G G F +G D+ + +A K + P L+ + S Q+ Sbjct: 85 TGEGP-TFSSGIDLDMF-QAGKVDGEPTPFTLLARDPNSTAALDQVIASYQEGFLWLRRA 142 Query: 134 --PYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQG-K 190 +A + G +G G L++ R+ ++ M E A+GL PD+ G L L G Sbjct: 143 DIVSIAAVRGHAIGAGFQLALSCDIRILSDTAQLCMKEPALGLVPDLTGTQPLVELVGVN 202 Query: 191 LGYFLALTGFRLKGRDVYRAGIATHFVDSEKLAMLEEDLLALKSPSKENIASVLENYHTE 250 L LT + + + +A V +L + L+A A + + Sbjct: 203 RAIELCLTARTIDAAEAAQLRLAERVVADAELDAAVDALVAQLLAVPAAAARATKELLLQ 262 Query: 251 SK 252 + Sbjct: 263 AG 264 >3HP0-A nrPDB Length = 267 Score = 147 bits (371), Expect = 8e-36, Method: Composition-based stats. Identities = 33/183 (18%), Positives = 74/183 (40%), Gaps = 3/183 (1%) Query: 34 AAEEVLLEKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKA 93 + + + + IT +RP+ N + +I + L + E +++++G + Sbjct: 5 TYQTIKVRFQASVCYITFHRPEANNTINDTLIEECLQVLNQCETS-TVTVVVLEGL-PEV 62 Query: 94 FCAGGDIRVISEAEKAKQKIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVH 153 FC G D + I + K +K A Y L + + ++ + G GG+G Sbjct: 63 FCFGADFQEIYQEMKRGRKQASSQ-EPLYDLWMKLQTGPYVTISHVRGKVNAGGLGFVSA 121 Query: 154 GQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGKLGYFLALTGFRLKGRDVYRAGIA 213 +A + F++ E GL+P + + R+ + +++ L + ++ G+ Sbjct: 122 TDIAIADQTASFSLSELLFGLYPACVLPFLIRRIGRQKAHYMTLMTKPISVQEASEWGLI 181 Query: 214 THF 216 F Sbjct: 182 DAF 184 >3HE2-A nrPDB Length = 264 Score = 147 bits (370), Expect = 1e-35, Method: Composition-based stats. Identities = 53/263 (20%), Positives = 95/263 (36%), Gaps = 27/263 (10%) Query: 38 VLLEKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCAG 97 + + + I L RP+ NAL ++ ++ ++K D I++ G G AFCAG Sbjct: 23 IGITQAEAVLTIELQRPERRNALNSQLVEELTQAIRKA-GDGSARAIVLTGQG-TAFCAG 80 Query: 98 GDIRVISEAEKAKQKIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFR 157 D+ + A ++ L+ A+ + P V I+G +G G+ L++ R Sbjct: 81 ADLSGDAFAADYPDRL--------IELHKAMDASPMPVVGAINGPAIGAGLQLAMQCDLR 132 Query: 158 VATEKCLFAMPETAIGLFPDVGGGYFLPRLQGK-LGYFLALTGFRLKGRDVYRAGIATHF 216 V F P + GL D L L G + L+ +L G+A Sbjct: 133 VVAPDAFFQFPTSKYGLALDNWSIRRLSSLVGHGRARAMLLSAEKLTAEIALHTGMANRI 192 Query: 217 VDSEKLAMLEEDLLALKSPSKENIASVLENYHTESKIDRDKSFILEE----HMDKINSCF 272 LA IA + +K + +EE H + + + Sbjct: 193 -----------GTLADAQAWAAEIARLAPLAIQHAKRVLNDDGAIEEAWPAHKELFDKAW 241 Query: 273 -SANTVEEIIENLQQDGSSFALE 294 S + +E + +++ F Sbjct: 242 GSQDVIEAQVARMEKRPPKFQGA 264 >3LAO-A nrPDB Length = 258 Score = 125 bits (313), Expect = 4e-29, Method: Composition-based stats. Identities = 54/259 (20%), Positives = 90/259 (34%), Gaps = 7/259 (2%) Query: 28 MSKHTDAAEEVLLEKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIK 87 MS+ V E++G +I L+R NA M+ + + ++E+ E+ ++ Sbjct: 4 MSEANSGPGRVTREQRGHLFLIGLDRAGKRNAFDSAMLADLALAMGEYERSEESRCAVLF 63 Query: 88 GAGGKAFCAGGDIRVISEAEKAKQKIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGG 147 G F AG D+ ++ A P + + + S KP V + G G Sbjct: 64 AHGE-HFTAGLDLMELAPKLAASGFRYPDGGVDPWGVVQPRRS--KPLVVAVQGTCWTAG 120 Query: 148 VGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQG-KLGYFLALTGFRLKGRD 206 + L ++ VA FA E G+ P G PR G LTG + Sbjct: 121 IELMLNADIAVAARGTRFAHLEVLRGIPPLGGSTVRFPRAAGWTDAMRYILTGDEFDADE 180 Query: 207 VYRAGIATHFV-DSEKLAMLEEDLLALKSPSKENIASVLENYHTESKIDRDKSFILEEHM 265 R + T V E+LA E A + +A D L Sbjct: 181 ALRMRLLTEVVEPGEELARALE--YAERIARAAPLAVRAALQSAFQGRDEGDDAALSRVN 238 Query: 266 DKINSCFSANTVEEIIENL 284 + + + + V E + + Sbjct: 239 ESLAALIGSEDVREGVLAM 257 >1XX4-A nrPDB Length = 261 Score = 120 bits (302), Expect = 8e-28, Method: Composition-based stats. Identities = 34/190 (17%), Positives = 71/190 (37%), Gaps = 9/190 (4%) Query: 38 VLLEKKG--CTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFC 95 VL+EK+G V+ P +N+L+L + + L+K E D +I+ F Sbjct: 6 VLVEKEGEAGIAVMKFKNPP-VNSLSLEFLTEFVISLEKLENDKSIRGVILTSERPGIFS 64 Query: 96 AGGDIRVISEAEKAKQKIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQ 155 AG D+ + A +++ L + ++ I+G + GG +++ Sbjct: 65 AGLDLMEMYGRNPAH---YAEYWKAVQELWLRLYLSNLTLISAINGASPAGGCLMALTCD 121 Query: 156 FRVATEKCL--FAMPETAIGLFPDVGGGYFLPRLQGKLGYFLAL-TGFRLKGRDVYRAGI 212 +R+ + + E+ +G+ G AL G + + G+ Sbjct: 122 YRIMADNSKYTIGLNESLLGIVAPFWLKDNYVNTIGHRAAERALQLGTLFPPAEALKVGL 181 Query: 213 ATHFVDSEKL 222 V +++ Sbjct: 182 VDEVVPEDQV 191 >2NP9-A nrPDB Length = 440 Score = 118 bits (296), Expect = 4e-27, Method: Composition-based stats. Identities = 45/245 (18%), Positives = 92/245 (37%), Gaps = 28/245 (11%) Query: 36 EEVLLEKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGA------ 89 E V LE++ +T+ R LNA + + + DP + +++G Sbjct: 167 EAVHLERRDGVARLTMCRDDRLNAEDGQQVDDMETAVDLALLDPGVRVGLLRGGVMSHPR 226 Query: 90 --GGKAFCAGGDIRVISEAE-------------KAKQKIAPVFFREEYMLNNAVGSCQKP 134 G + F AG +++ +S+ + + V ++ +KP Sbjct: 227 YRGKRVFSAGINLKYLSQGGISLVDFLMRRELGYIHKLVRGVLTNDDRPGWWHSPRIEKP 286 Query: 135 YVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQG-KLGY 193 +VA + G +GGG L + +A+ F++P G+ P L R G ++ Sbjct: 287 WVAAVDGFAIGGGAQLLLVFDRVLASSDAYFSLPAAKEGIIPGA-ANLRLGRFAGPRVSR 345 Query: 194 FLALTGFRLKGRDVYRAGIATHFVDSEKLAMLEEDLLALKSPSKENIASVLENYHTESKI 253 + L G R+ ++ + V+ ++L +S ++ + +VL N + Sbjct: 346 QVILEGRRIWAKEPEARLLVDEVVEPDELDA-----AIERSLTRLDGDAVLANRRMLNLA 400 Query: 254 DRDKS 258 D Sbjct: 401 DESPD 405 >4B3J-A nrPDB Length = 736 Score = 105 bits (262), Expect = 3e-23, Method: Composition-based stats. Identities = 45/221 (20%), Positives = 84/221 (38%), Gaps = 10/221 (4%) Query: 44 GCTGVITLNRPK-FLNALTLNMIRQIYPQLKK--WEQDPETFLIIIKGAGGKAFCAGGDI 100 +T++ P N + I + + + E+D T +++ + K F AGGD+ Sbjct: 29 DGIVTLTMDDPSGSTNVMNEAYIESMGKAVDRLVAEKDSITGVVV--ASAKKTFFAGGDV 86 Query: 101 RVISEAEKAKQKIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVAT 160 + + +A + + KP VA I+G +GGG+ +++ R+A Sbjct: 87 KTMIQARPEDAGDVFNTVETIKRQLRTLETLGKPVVAAINGAALGGGLEIALACHHRIAA 146 Query: 161 E--KCLFAMPETAIGLFPDVGGGYFLPRLQG-KLGYFLALT-GFRLKGRDVYRAGIATHF 216 + +PE +GL P GG R+ G + + L G R K G+ Sbjct: 147 DVKGSQLGLPEVTLGLLPGGGGVTRTVRMFGIQNAFVSVLAQGTRFKPAKAKEIGLVDEL 206 Query: 217 VD-SEKLAMLEEDLLALKSPSKENIASVLENYHTESKIDRD 256 V E+L + + + + + A V K+ Sbjct: 207 VATVEELVPAAKAWIKEELKANPDGAGVQPWDKKGYKMPGG 247 >4Q1J-A nrPDB Length = 268 Score = 97.5 bits (241), Expect = 9e-21, Method: Composition-based stats. Identities = 37/228 (16%), Positives = 85/228 (37%), Gaps = 8/228 (3%) Query: 39 LLEKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCAGG 98 L+E + + + NA + + + + Q+P+ +I+ G F +GG Sbjct: 27 LIEIESAIIQVKMQDRTHKNAFSQELTDDLIQAFEYIRQNPKYKAVILTGY-DNYFASGG 85 Query: 99 DIRVISEAEKAKQKIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRV 158 + ++ K + L + C+ P +A + G +GGG + + + Sbjct: 86 TQEGLLRIQQGLTKFT------DDNLYSLALDCEIPVIAAMQGHGIGGGFVMGLFADIVI 139 Query: 159 ATEKCLFAMPETAIGLFPDVGGGYFLPRLQG-KLGYFLALTGFRLKGRDVYRAGIATHFV 217 + + ++ G P +G + +P+ G L + L +G D+ + G+ + Sbjct: 140 LSRESVYTANFMKYGFTPGMGATFIVPKKLGFSLAQEILLNAGSYRGADLEKRGVPFKVL 199 Query: 218 DSEKLAMLEEDLLALKSPSKENIASVLENYHTESKIDRDKSFILEEHM 265 ++ +L + N L+++ D+ I +E M Sbjct: 200 PRAEVLDYAVELAQELAEKPRNSLVTLKDHLVAPLRDQLPRVIEQELM 247 >4HC8-A nrPDB Length = 255 Score = 90.6 bits (223), Expect = 1e-18, Method: Composition-based stats. Identities = 44/190 (23%), Positives = 70/190 (36%), Gaps = 13/190 (6%) Query: 35 AEEVLLEKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAF 94 ++ V +K VI+++ +NAL M + + + ++D + ++I G G+ F Sbjct: 4 SDPVSYTRKDSIAVISMDDG-KVNALGPAMQQALNAAIDNADRD-DVGALVITG-NGRVF 60 Query: 95 CAGGDIRVISEAEKAKQKIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHG 154 G D+++++ E A R + L + S KP V G + G L G Sbjct: 61 SGGFDLKILTSGEVQP---AIDMLRGGFELAYRLLSYPKPVVMACTGHAIAMGAFLLSCG 117 Query: 155 QFRVATEKCLFAMPETAIGL-FPDVGG---GYFLPRLQGKLGYFLALTGFRLKGRDVYRA 210 RVA E AIG+ P L R + LA T G A Sbjct: 118 DHRVAAHAYNIQANEVAIGMTIPYAALEIMKLRLTRSAYQQATGLAKT---FFGETALAA 174 Query: 211 GIATHFVDSE 220 G E Sbjct: 175 GFIDEIALPE 184 >3M6N-A nrPDB Length = 305 Score = 86.3 bits (212), Expect = 2e-17, Method: Composition-based stats. Identities = 34/243 (13%), Positives = 81/243 (33%), Gaps = 23/243 (9%) Query: 38 VLLEKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQD-----PETFLI---IIKGA 89 ++ E + I ++ +N ++ + ++ + ++ ++ + Sbjct: 34 IIEEPQRDVYWIHMHADLAINPGRACFSTRLVDDITGYQTNLGQRLNTAGVLAPHVVLAS 93 Query: 90 GGKAFCAGGDIRVISEAEKAKQKIAPVFFREEYMLNNAVGSCQKPY------VALIHGIT 143 F GGD+ + + + + V + +AL+ G Sbjct: 94 DSDVFNLGGDLALFCQLIREGDR--ARLLDYAQRCVRGVHAFHVGLGARAHSIALVQGNA 151 Query: 144 MGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGG-GYFLPRLQGKLGYFLALTGFRL 202 +GGG ++ +A E + +PE LFP +G + R+ L + L G Sbjct: 152 LGGGFEAALSCHTIIAEEGVMMGLPEVLFDLFPGMGAYSFMCQRISAHLAQKIMLEGNLY 211 Query: 203 KGRDVYRAGIATHFVDSEKLAMLEEDLLALKSPSKENIASVLENYHTESKIDRDKSFILE 262 + G+ V + + A++ +E+ + + + + LE Sbjct: 212 SAEQLLGMGLVDRVVPRG------QGVAAVEQVIRESKRTPHAWAAMQQVREMTTAVPLE 265 Query: 263 EHM 265 E M Sbjct: 266 EMM 268 >4ZDC-A nrPDB Length = 300 Score = 79.4 bits (194), Expect = 2e-15, Method: Composition-based stats. Identities = 34/167 (20%), Positives = 64/167 (38%), Gaps = 10/167 (5%) Query: 28 MSKHTDAAEEVLLEKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIK 87 MS+ E++ +G +I L P LNAL + L+ +++ + + II+ Sbjct: 21 MSQEIRQNEKISYRIEGPFFIIHLINPDNLNALEGEDYIYLGELLELADRNRDVYFTIIQ 80 Query: 88 GAGGKAFCAGGDIRVISEAEKAKQ--------KIAPVFFREEYMLNNAVGSCQKPYVALI 139 +G + F +G D + I++A+ K F + +A K + + Sbjct: 81 SSG-RFFSSGADFKGIAKAQGDDTNKYPSETSKWVSNFVARNVYVTDAFIKHSKVLICCL 139 Query: 140 HGITMGGGVGLSVHGQFRVA-TEKCLFAMPETAIGLFPDVGGGYFLP 185 +G +G L + +K P +GL + G LP Sbjct: 140 NGPAIGLSAALVALCDIVYSINDKVYLLYPFANLGLITEGGTTVSLP 186 >1ON3-A nrPDB Length = 523 Score = 35.5 bits (80), Expect = 0.040, Method: Composition-based stats. Identities = 20/107 (18%), Positives = 33/107 (30%), Gaps = 18/107 (16%) Query: 134 PYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGKLGY 193 P +A+I G GG F + T+K + G + + G+ Sbjct: 169 PQIAIIAGPCAGGASYSPALTDFIIMTKKAHMFIT-----------GPQVIKSVTGED-- 215 Query: 194 FLALTGFRLKGRDVYRA--GIATHFVDSEKLAMLEEDLLALKSPSKE 238 +T L G + + A G + + A L L P Sbjct: 216 ---VTADELGGAEAHMAISGNIHFVAEDDDAAELIAKKLLSFLPQNN 259 >3RZZ-A nrPDB Length = 446 Score = 33.9 bits (76), Expect = 0.12, Method: Composition-based stats. Identities = 20/122 (16%), Positives = 41/122 (33%), Gaps = 1/122 (0%) Query: 260 ILEEHMDKINSCFSANTVEEIIENLQQDGSSFALEQLKVINKMSPTSLKITLRQLMEGSS 319 EE + ++ SA +V ++ + + A E V +L+ + Sbjct: 220 AFEEALKALSGKVSAGSVLDLFLARRAHTRTSAAEAAGVPPADLEAALRSPASETGLTVL 279 Query: 320 KTLQEVLTMEYRLSQACMRGHDFHEGVRAVLIDKDQSPKWKPADLKEVTEEDLNNHFKSL 379 +TL L +YR+ HD + D +S + + + + + Sbjct: 280 RTLGRALGFDYRVLLPADDQHDGVGKTWTTIEDSRRSRR-TFGTYEAASMASAAHLPDLV 338 Query: 380 GS 381 GS Sbjct: 339 GS 340 >3U9S-B nrPDB Length = 555 Score = 33.5 bits (75), Expect = 0.15, Method: Composition-based stats. Identities = 27/173 (15%), Positives = 59/173 (34%), Gaps = 33/173 (19%) Query: 95 CAGGDIRVISEAEKAKQKIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHG 154 G ++ E ++ +FF + M + P +A++ G GG + Sbjct: 165 SGGANLPRQDEVFPDREHFGRIFFNQANMSARGI-----PQIAVVMGSCTAGGAYVPAMS 219 Query: 155 QFRVA--TEKCLFAMPETAIGLFPDVGGGYFLPRLQGKLGYFLALTGFRLKGRDVY--RA 210 V + +F + G + G+ ++ L G DV+ + Sbjct: 220 DETVMVREQATIF------------LAGPPLVKAATGE-----VVSAEELGGADVHCKVS 262 Query: 211 GIATHFVDSEKLAMLEEDLLALKSPSKENIASVLENYHTESKIDRDKSFILEE 263 G+A H+ + + A+ +A + + N + + + R + EE Sbjct: 263 GVADHYAEDDDHAL----AIARRCVANLNWR---KQGQLQCRAPRAPLYPAEE 308 >3BF0-A nrPDB Length = 593 Score = 32.4 bits (72), Expect = 0.34, Method: Composition-based stats. Identities = 28/158 (17%), Positives = 45/158 (28%), Gaps = 34/158 (21%) Query: 24 HHLRMSKHTDAAEEVLLEKKGCTGVITLNR------PKFLNALTLNMIRQIYPQLKKWEQ 77 + R + D A + + GV+ N N QI Sbjct: 281 KNYRAISYYDYALKTPADTGDSIGVVFANGAIMDGEETQGNVGGDTTAAQIRDA----RL 336 Query: 78 DPETFLIIIKGAGGKAFCAGGDIRVISEAEKAKQKIAPVFFREEYMLNNAVGSCQKPYVA 137 DP+ I++ + GG + A + KP V Sbjct: 337 DPKVKAIVL-----RVNSPGGSVTA---------------SEVIRAELAAARAAGKPVVV 376 Query: 138 LIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLF 175 + G+ GG +S + VA L +IG+F Sbjct: 377 SMGGMAASGGYWISTPANYIVANPSTLTG----SIGIF 410 >2V8U-A nrPDB Length = 302 Score = 31.6 bits (70), Expect = 0.52, Method: Composition-based stats. Identities = 11/60 (18%), Positives = 20/60 (33%), Gaps = 4/60 (6%) Query: 56 FLN--ALTLNMIRQIYPQLKKWEQDPETFLIIIKG--AGGKAFCAGGDIRVISEAEKAKQ 111 N + R + K + T ++++ G GG F AG D + + Sbjct: 230 HRNLYRFSPEDYRDLGLIWKGASPEDGTEVVVVDGPPTGGPVFDAGHDAAEFAPEFHPGE 289 >5XXB-G nrPDB Length = 276 Score = 30.5 bits (67), Expect = 1.3, Method: Composition-based stats. Identities = 14/71 (19%), Positives = 29/71 (40%), Gaps = 2/71 (2%) Query: 15 AFKRTNTILHHLRMSKHTDAAEEVLLEKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKK 74 +F+ I +S+ + +LL+++ + L P +N T + + QL + Sbjct: 46 SFRVGGNIQPRRDLSRFVKWPKYILLQRQRRVLMQRLKVPPAINQFTHTLDKNQTSQLMR 105 Query: 75 --WEQDPETFL 83 + PET Sbjct: 106 LLAKYKPETRA 116 >2YV2-A nrPDB Length = 297 Score = 30.5 bits (67), Expect = 1.3, Method: Composition-based stats. Identities = 16/78 (20%), Positives = 27/78 (34%), Gaps = 24/78 (30%) Query: 67 QIYPQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRVISEAEKAKQKIAPVFFREEYMLNN 126 LK +++DP+T +++ G GGD+ + K + Sbjct: 193 SFTEALKLFQEDPQTEALVLIGE------IGGDMEERAAEMIKKGE-------------- 232 Query: 127 AVGSCQKPYVALIHGITM 144 KP +A I G T Sbjct: 233 ----FTKPVIAYIAGRTA 246 >3GTD-A nrPDB Length = 482 Score = 30.1 bits (66), Expect = 1.7, Method: Composition-based stats. Identities = 12/58 (20%), Positives = 23/58 (39%) Query: 110 KQKIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAM 167 KQ+ + + EY L + +K Y+ G +G G+ + + A + F Sbjct: 219 KQEFSGYITQIEYALERIEDALKKVYLLAQGGTAVGTGINSKIGFDIKFAQKVAEFTQ 276 >1SKF-A nrPDB Length = 262 Score = 29.7 bits (65), Expect = 2.2, Method: Composition-based stats. Identities = 8/30 (26%), Positives = 12/30 (40%), Gaps = 3/30 (10%) Query: 131 CQKPYVALIHGITMGGGVGLSV---HGQFR 157 KP +A + G M G G ++ R Sbjct: 1 VTKPTIAAVGGYAMNNGTGTTLYTKAADTR 30 >4Q0G-A nrPDB Length = 529 Score = 29.7 bits (65), Expect = 2.5, Method: Composition-based stats. Identities = 22/134 (16%), Positives = 45/134 (33%), Gaps = 26/134 (19%) Query: 95 CAGGDIRVISEAEKAKQKIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHG 154 G + E ++ +F+ + M + P VA + G GG + Sbjct: 139 SGGAFLPRQDEVFPDREHFGRIFYNQATMSAKGI-----PQVAAVLGSCTAGGAYVPAMS 193 Query: 155 Q--FRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGKLGYFLALTGFRLKGRDVYR--A 210 V + +F +GG + G+ ++ L G D++ + Sbjct: 194 DEAVIVREQGTIF------------LGGPPLVKAATGE-----IVSAEELGGGDLHSRTS 236 Query: 211 GIATHFVDSEKLAM 224 G+ H D ++ A+ Sbjct: 237 GVTDHLADDDEDAL 250 >2C82-A nrPDB Length = 413 Score = 27.8 bits (60), Expect = 9.4, Method: Composition-based stats. Identities = 27/139 (19%), Positives = 48/139 (34%), Gaps = 5/139 (3%) Query: 239 NIASVLENYHTESKIDRDKSFILEEHMDKINSCFSANTVEE-IIENLQQDGSSFALEQLK 297 NIA E+ D + + ++ A+ V ++ L + AL+ Sbjct: 65 NIAVADEHAAQRVG---DIPYHGSDAATRLVEQTEADVVLNALVGALGLRPTLAALKTGA 121 Query: 298 VINKMSPTSLKITLRQLMEGSSKTLQEVLTMEYRLSQACMRGHDFHEGVRAVLIDKDQSP 357 + + SL ++ + + E+ C+RG E + VL Sbjct: 122 RLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPF 181 Query: 358 K-WKPADLKEVTEEDLNNH 375 + W ADL+ VT E H Sbjct: 182 RGWSAADLEHVTPEQAGAH 200 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.308 0.130 0.331 Lambda K H 0.267 0.0400 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 13,188,196 Number of Sequences: 36641 Number of extensions: 518861 Number of successful extensions: 1852 Number of sequences better than 10.0: 66 Number of HSP's better than 10.0 without gapping: 107 Number of HSP's successfully gapped in prelim test: 28 Number of HSP's that attempted gapping in prelim test: 1530 Number of HSP's gapped (non-prelim): 148 length of query: 386 length of database: 10,336,785 effective HSP length: 99 effective length of query: 287 effective length of database: 6,709,326 effective search space: 1925576562 effective search space used: 1925576562 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 60 (27.8 bits)