BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q6NUA1 (633 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 4G56-A nrPDB 1323 0.0 5FA5-A nrPDB 1143 0.0 3UA4-A nrPDB 304 9e-83 3B3J-A nrPDB 56 5e-08 4IKP-A nrPDB 55 7e-08 5IS8-A nrPDB 55 8e-08 1F3L-A nrPDB 49 8e-06 5JMQ-A nrPDB 47 3e-05 4M36-A nrPDB 45 7e-05 3R0Q-C nrPDB 45 8e-05 4RYL-A nrPDB 45 1e-04 1G6Q-1 nrPDB 45 1e-04 3X0D-A nrPDB 45 1e-04 5EKU-A nrPDB 45 1e-04 3Q7E-A nrPDB 42 7e-04 5LV5-A nrPDB 41 0.001 5EGS-A nrPDB 40 0.002 5FUB-A nrPDB 37 0.022 1RF6-A nrPDB 34 0.15 4KNH-A nrPDB 34 0.20 5DST-A nrPDB 34 0.24 2ICS-A nrPDB 34 0.24 3A27-A nrPDB 32 0.93 1L3B-A nrPDB 31 1.5 1R19-A nrPDB 31 1.7 4E9V-A nrPDB 30 3.3 6CU3-A nrPDB 29 4.9 5MTZ-A nrPDB 29 5.5 6GWU-A nrPDB 29 6.0 1M4N-A nrPDB 29 6.2 >4G56-A nrPDB Length = 657 Score = 1323 bits (3423), Expect = 0.0, Method: Compositional matrix adjust. Identities = 632/632 (100%), Positives = 632/632 (100%) Query: 2 AAGDGGRVSSGRDVACVTEVADTLGAMANQGFDFLCMPIFHPRFKREFYKEPAKSRPGPQ 61 AAGDGGRVSSGRDVACVTEVADTLGAMANQGFDFLCMPIFHPRFKREFYKEPAKSRPGPQ Sbjct: 26 AAGDGGRVSSGRDVACVTEVADTLGAMANQGFDFLCMPIFHPRFKREFYKEPAKSRPGPQ 85 Query: 62 TRSDLLLSGRDWNTLIVGKLSDWIKTDSEVSRIRKTSEAAMQQELNFSAYLGLPAFLIPL 121 TRSDLLLSGRDWNTLIVGKLSDWIKTDSEVSRIRKTSEAAMQQELNFSAYLGLPAFLIPL Sbjct: 86 TRSDLLLSGRDWNTLIVGKLSDWIKTDSEVSRIRKTSEAAMQQELNFSAYLGLPAFLIPL 145 Query: 122 KQEDNSNLSRLLINHIHVGHHSTMFWMRVPLMAPNDLRDDLIENEPISLSEEDNSGEERT 181 KQEDNSNLSRLLINHIHVGHHSTMFWMRVPLMAPNDLRDDLIENEPISLSEEDNSGEERT Sbjct: 146 KQEDNSNLSRLLINHIHVGHHSTMFWMRVPLMAPNDLRDDLIENEPISLSEEDNSGEERT 205 Query: 182 WIWWHNFRSLCDYNKKIALAIEIGADLPSGHVIDRWLGEPIKAAFLPTSIFLTNKKGFPV 241 WIWWHNFRSLCDYNKKIALAIEIGADLPSGHVIDRWLGEPIKAAFLPTSIFLTNKKGFPV Sbjct: 206 WIWWHNFRSLCDYNKKIALAIEIGADLPSGHVIDRWLGEPIKAAFLPTSIFLTNKKGFPV 265 Query: 242 LTKVHQRLIFKLFKLEVQFVISGSHHHSEKDLCSYLQYLEYLSQNSPPPNAYEMFAKGYE 301 LTKVHQRLIFKLFKLEVQFVISGSHHHSEKDLCSYLQYLEYLSQNSPPPNAYEMFAKGYE Sbjct: 266 LTKVHQRLIFKLFKLEVQFVISGSHHHSEKDLCSYLQYLEYLSQNSPPPNAYEMFAKGYE 325 Query: 302 DYLQSPLQPLMDNLESQTYEVFEKDPVKYSQYQQAVYKCLLDRVPEEEKETNIQILMVLG 361 DYLQSPLQPLMDNLESQTYEVFEKDPVKYSQYQQAVYKCLLDRVPEEEKETNIQILMVLG Sbjct: 326 DYLQSPLQPLMDNLESQTYEVFEKDPVKYSQYQQAVYKCLLDRVPEEEKETNIQILMVLG 385 Query: 362 AGRGPLVNASLRAAKQAERKIKVYAVEKNPNAVITLEGWRYEEWGSQVTVVSGDMREWKA 421 AGRGPLVNASLRAAKQAERKIKVYAVEKNPNAVITLEGWRYEEWGSQVTVVSGDMREWKA Sbjct: 386 AGRGPLVNASLRAAKQAERKIKVYAVEKNPNAVITLEGWRYEEWGSQVTVVSGDMREWKA 445 Query: 422 PEKADIIVSELLGSFGDNELSPECLDGAQHFLKDDGVSIPGEYTSYLAPISSSKLYNEVR 481 PEKADIIVSELLGSFGDNELSPECLDGAQHFLKDDGVSIPGEYTSYLAPISSSKLYNEVR Sbjct: 446 PEKADIIVSELLGSFGDNELSPECLDGAQHFLKDDGVSIPGEYTSYLAPISSSKLYNEVR 505 Query: 482 ACREKDRDPEAQFEMPYVVRLHNFHQLSDPLPCFTFHHPNKDDVIDNNRYCCLQYRVDLN 541 ACREKDRDPEAQFEMPYVVRLHNFHQLSDPLPCFTFHHPNKDDVIDNNRYCCLQYRVDLN Sbjct: 506 ACREKDRDPEAQFEMPYVVRLHNFHQLSDPLPCFTFHHPNKDDVIDNNRYCCLQYRVDLN 565 Query: 542 TVLHGFAGYFNTVLYKDVTLSICPESHSPGMFSWFPILFPIKQPIPMREGDTVCVRFWRC 601 TVLHGFAGYFNTVLYKDVTLSICPESHSPGMFSWFPILFPIKQPIPMREGDTVCVRFWRC Sbjct: 566 TVLHGFAGYFNTVLYKDVTLSICPESHSPGMFSWFPILFPIKQPIPMREGDTVCVRFWRC 625 Query: 602 NNGKKVWYEWAVTSPVCSAIHNPTGRSYTIGL 633 NNGKKVWYEWAVTSPVCSAIHNPTGRSYTIGL Sbjct: 626 NNGKKVWYEWAVTSPVCSAIHNPTGRSYTIGL 657 >5FA5-A nrPDB Length = 650 Score = 1143 bits (2956), Expect = 0.0, Method: Compositional matrix adjust. Identities = 527/627 (84%), Positives = 587/627 (93%), Gaps = 1/627 (0%) Query: 7 GRVSSGRDVACVTEVADTLGAMANQGFDFLCMPIFHPRFKREFYKEPAKSRPGPQTRSDL 66 RVSSGRD+ CV E+ADTLGA+A QGFDFLCMP+FHPRFKREF +EPAK+RPGPQTRSDL Sbjct: 25 SRVSSGRDLNCVPEIADTLGAVAKQGFDFLCMPVFHPRFKREFIQEPAKNRPGPQTRSDL 84 Query: 67 LLSGRDWNTLIVGKLSDWIKTDSEVSRIRKTSEAAMQQELNFSAYLGLPAFLIPLKQEDN 126 LLSGRDWNTLIVGKLS WI+ DS+V +IR+ SEAAM QELNF AYLGLPAFL+PL QEDN Sbjct: 85 LLSGRDWNTLIVGKLSPWIRPDSKVEKIRRNSEAAMLQELNFGAYLGLPAFLLPLNQEDN 144 Query: 127 SNLSRLLINHIHVGHHSTMFWMRVPLMAPNDLRDDLIENEPISLSEEDNSGEERTWIWWH 186 +NL+R+L NHIH GHHS+MFWMRVPL+AP DLRDD+IEN P + +EE SGEE+TW+WWH Sbjct: 145 TNLARVLTNHIHTGHHSSMFWMRVPLVAPEDLRDDIIENAPTTHTEE-YSGEEKTWMWWH 203 Query: 187 NFRSLCDYNKKIALAIEIGADLPSGHVIDRWLGEPIKAAFLPTSIFLTNKKGFPVLTKVH 246 NFR+LCDY+K+IA+A+EIGADLPS HVIDRWLGEPIKAA LPTSIFLTNKKGFPVL+K+H Sbjct: 204 NFRTLCDYSKRIAVALEIGADLPSNHVIDRWLGEPIKAAILPTSIFLTNKKGFPVLSKMH 263 Query: 247 QRLIFKLFKLEVQFVISGSHHHSEKDLCSYLQYLEYLSQNSPPPNAYEMFAKGYEDYLQS 306 QRLIF+L KLEVQF+I+G++HHSEK+ CSYLQYLEYLSQN PPPNAYE+FAKGYEDYLQS Sbjct: 264 QRLIFRLLKLEVQFIITGTNHHSEKEFCSYLQYLEYLSQNRPPPNAYELFAKGYEDYLQS 323 Query: 307 PLQPLMDNLESQTYEVFEKDPVKYSQYQQAVYKCLLDRVPEEEKETNIQILMVLGAGRGP 366 PLQPLMDNLESQTYEVFEKDP+KYSQYQQA+YKCLLDRVPEEEK+TN+Q+LMVLGAGRGP Sbjct: 324 PLQPLMDNLESQTYEVFEKDPIKYSQYQQAIYKCLLDRVPEEEKDTNVQVLMVLGAGRGP 383 Query: 367 LVNASLRAAKQAERKIKVYAVEKNPNAVITLEGWRYEEWGSQVTVVSGDMREWKAPEKAD 426 LVNASLRAAKQA+R+IK+YAVEKNPNAV+TLE W++EEWGSQVTVVS DMREW APEKAD Sbjct: 384 LVNASLRAAKQADRRIKLYAVEKNPNAVVTLENWQFEEWGSQVTVVSSDMREWVAPEKAD 443 Query: 427 IIVSELLGSFGDNELSPECLDGAQHFLKDDGVSIPGEYTSYLAPISSSKLYNEVRACREK 486 IIVSELLGSF DNELSPECLDGAQHFLKDDGVSIPGEYTS+LAPISSSKLYNEVRACREK Sbjct: 444 IIVSELLGSFADNELSPECLDGAQHFLKDDGVSIPGEYTSFLAPISSSKLYNEVRACREK 503 Query: 487 DRDPEAQFEMPYVVRLHNFHQLSDPLPCFTFHHPNKDDVIDNNRYCCLQYRVDLNTVLHG 546 DRDPEAQFEMPYVVRLHNFHQLS P PCFTF HPN+D +IDNNRYC L++ V++NTVLHG Sbjct: 504 DRDPEAQFEMPYVVRLHNFHQLSAPQPCFTFSHPNRDPMIDNNRYCTLEFPVEVNTVLHG 563 Query: 547 FAGYFNTVLYKDVTLSICPESHSPGMFSWFPILFPIKQPIPMREGDTVCVRFWRCNNGKK 606 FAGYF TVLY+D+TLSI PE+HSPGMFSWFPILFPIKQPI +REG T+CVRFWRC+N KK Sbjct: 564 FAGYFETVLYQDITLSIRPETHSPGMFSWFPILFPIKQPITVREGQTICVRFWRCSNSKK 623 Query: 607 VWYEWAVTSPVCSAIHNPTGRSYTIGL 633 VWYEWAVT+PVCSAIHNPTGRSYTIGL Sbjct: 624 VWYEWAVTAPVCSAIHNPTGRSYTIGL 650 >3UA4-A nrPDB Length = 745 Score = 304 bits (778), Expect = 9e-83, Method: Compositional matrix adjust. Identities = 207/647 (31%), Positives = 310/647 (47%), Gaps = 91/647 (14%) Query: 53 PAKSRPGPQTRSDLLLSGRDWNTLIVGKLSDWIKTDSEVSRIRKTSEAAMQQELNFSAYL 112 P P Q R+DL W + +VGK+S WI DS SE + +EL++ YL Sbjct: 108 PVIDLPDVQLRNDL------WESYVVGKISPWIDCDSSDPAFASLSEEHLLKELSYICYL 161 Query: 113 GLPAFLIPLKQEDNSNLSRLLINHIHVGHHSTMFWMRVPLMAPNDLRDDLIENEPISLSE 172 GL I L + + + +L I + W+++P D E + L Sbjct: 162 GLQTMAIELTRISSPRTAAILKKWIWTRNSRFTVWVQLPSAIEKCKDYDAFTIEHVDL-- 219 Query: 173 EDNSGEERTWIWWHNFRSLCDYNKKI--ALAIEIGADLPSG----HVIDRWLGEPIKAAF 226 W W +FR C + +A+ I ++LP ++DRW EP+ A Sbjct: 220 ---------WTIWADFRKNCGNFSGVYFQVALTISSELPDELTELKLVDRWKAEPLAAFV 270 Query: 227 LPTSIFLTNKKGFPVLTKVHQRLIFKLFKLEVQFVI----SGSHHHSEKDLCSYLQYLEY 282 + + +F++ + G + H L+ L+ + ++ + + ++ Y Q L + Sbjct: 271 IESGLFISGRNGEASIPSAHINLLKHLWTTDALRIVLRATTDTFKYNTSIKSEYSQALRH 330 Query: 283 LSQN----SPPP-------NAYEMFAKGYEDYLQSPLQPLMDNLESQTYEVFEKDPVKYS 331 +N S P + + + Y+D LQ+PLQPL +NL+S Y FE+D +KY Sbjct: 331 AVRNVNYRSRPDVGEGSNDSTHYLNVIEYKDVLQAPLQPLSENLDSGVYNTFEQDQIKYD 390 Query: 332 QYQQAVYKCLLDRVPEEEKETNIQILMVLGAGRGPLVNASLRAAK---------QAERKI 382 Y +AV L D + K ++ +LG GRGP+ L++ + Q K+ Sbjct: 391 VYGEAVVGALKDLGADGRKTV---VIYLLGGGRGPIGTKILKSEREYNNTFRQGQESLKV 447 Query: 383 KVYAVEKNPNAVITLEGWRYEEWGSQVTVVSGDMREW------KAPEKADIIVSELLGSF 436 K+Y VEKNPNA++TL+ W +VT++ DMR + E+ DIIVSELLGSF Sbjct: 448 KLYIVEKNPNAIVTLKYMNVRTWKRRVTIIESDMRSLPGIAKDRGFEQPDIIVSELLGSF 507 Query: 437 GDNELSPECLDGAQHFLKDDGVSIPGEYTSYLAPISSSKLYNEVRACR------------ 484 GDNELSPECLDG FLK +SIP +YTSY+ PI S+ ++ ++A Sbjct: 508 GDNELSPECLDGVTGFLKPTTISIPQKYTSYVKPIMSTHIHQTIKAQSIPYLSRAIPSHG 567 Query: 485 ----EKDRD-------PEAQ----FEMPYVVRLHNFHQLSDPL-PCFTFHHPNKDDVIDN 528 E D D P+ + YVV L + L++ P FTF HPN + N Sbjct: 568 RGEPELDEDEMWIQKYPQGHVRNNMDQIYVVYLSKYIPLAETTKPVFTFEHPNFMNS-SN 626 Query: 529 NRYCCLQYRVDLNTVLHGFAGYFNTVLYKDVTLSICPESHSPGMFSWFPILFPIKQPIPM 588 R +++ +D N L GFAGYF+ LYK V LSI P +H+PGM SWFP + P++ + + Sbjct: 627 ERSDSIEFVMDRNADLMGFAGYFDLQLYKTVMLSIEPSTHTPGMVSWFPAVIPLRDQLRV 686 Query: 589 REGDTVCVRFWRCNNGKKVWYEWAVTS------PVCSAIHNPTGRSY 629 EGD + ++ R + VWYEW V V + I NP G SY Sbjct: 687 GEGDRISLKIDRKVDNTGVWYEWHVEKKKTNGESVSTPIQNPNGESY 733 >3B3J-A nrPDB Length = 480 Score = 55.8 bits (133), Expect = 5e-08, Method: Compositional matrix adjust. Identities = 46/155 (29%), Positives = 71/155 (45%), Gaps = 13/155 (8%) Query: 325 KDPVKYSQYQQAVYKCLLDRVPEEEKETNIQILMVLGAGRGPLVNASLRAAKQAERKIKV 384 +D V+ YQ+A+ + + +I++ +G G G L S AA+ RKI Sbjct: 138 QDYVRTGTYQRAIL--------QNHTDFKDKIVLDVGCGSGIL---SFFAAQAGARKI-- 184 Query: 385 YAVEKNPNAVITLEGWRYEEWGSQVTVVSGDMREWKAPEKADIIVSELLGSFGDNELSPE 444 YAVE + A + ++ V+ G + E PE+ DII+SE +G NE E Sbjct: 185 YAVEASTMAQHAEVLVKSNNLTDRIVVIPGKVEEVSLPEQVDIIISEPMGYMLFNERMLE 244 Query: 445 CLDGAQHFLKDDGVSIPGEYTSYLAPISSSKLYNE 479 A+ +LK G P +LAP + +LY E Sbjct: 245 SYLHAKKYLKPSGNMFPTIGDVHLAPFTDEQLYME 279 >4IKP-A nrPDB Length = 341 Score = 55.5 bits (132), Expect = 7e-08, Method: Compositional matrix adjust. Identities = 46/155 (29%), Positives = 71/155 (45%), Gaps = 13/155 (8%) Query: 325 KDPVKYSQYQQAVYKCLLDRVPEEEKETNIQILMVLGAGRGPLVNASLRAAKQAERKIKV 384 +D V+ YQ+A+ + + +I++ +G G G L S AA+ RKI Sbjct: 25 QDYVRTGTYQRAIL--------QNHTDFKDKIVLDVGCGSGIL---SFFAAQAGARKI-- 71 Query: 385 YAVEKNPNAVITLEGWRYEEWGSQVTVVSGDMREWKAPEKADIIVSELLGSFGDNELSPE 444 YAVE + A + ++ V+ G + E PE+ DII+SE +G NE E Sbjct: 72 YAVEASTMAQHAEVLVKSNNLTDRIVVIPGKVEEVSLPEQVDIIISEPMGYMLFNERMLE 131 Query: 445 CLDGAQHFLKDDGVSIPGEYTSYLAPISSSKLYNE 479 A+ +LK G P +LAP + +LY E Sbjct: 132 SYLHAKKYLKPSGNMFPTIGDVHLAPFTDEQLYME 166 >5IS8-A nrPDB Length = 381 Score = 55.5 bits (132), Expect = 8e-08, Method: Compositional matrix adjust. Identities = 46/155 (29%), Positives = 71/155 (45%), Gaps = 13/155 (8%) Query: 325 KDPVKYSQYQQAVYKCLLDRVPEEEKETNIQILMVLGAGRGPLVNASLRAAKQAERKIKV 384 +D V+ YQ+A+ + + +I++ +G G G L S AA+ RKI Sbjct: 39 QDYVRTGTYQRAIL--------QNHTDFKDKIVLDVGCGSGIL---SFFAAQAGARKI-- 85 Query: 385 YAVEKNPNAVITLEGWRYEEWGSQVTVVSGDMREWKAPEKADIIVSELLGSFGDNELSPE 444 YAVE + A + ++ V+ G + E PE+ DII+SE +G NE E Sbjct: 86 YAVEASTMAQHAEVLVKSNNLTDRIVVIPGKVEEVSLPEQVDIIISEPMGYMLFNERMLE 145 Query: 445 CLDGAQHFLKDDGVSIPGEYTSYLAPISSSKLYNE 479 A+ +LK G P +LAP + +LY E Sbjct: 146 SYLHAKKYLKPSGNMFPTIGDVHLAPFTDEQLYME 180 >1F3L-A nrPDB Length = 321 Score = 48.5 bits (114), Expect = 8e-06, Method: Compositional matrix adjust. Identities = 66/291 (22%), Positives = 121/291 (41%), Gaps = 37/291 (12%) Query: 320 YEVFEKDPVKYSQYQQAVYKCLLDRVPEEEKETNIQILMVLGAGRGPLVNASLRAAKQAE 379 +E KD V+ Y+ +Y+ P K+ ++++ +G G G L S+ AAK Sbjct: 20 HEEMLKDKVRTESYRDFIYQN-----PHIFKD---KVVLDVGCGTGIL---SMFAAKAGA 68 Query: 380 RKIKVYAVEKNPNAVITLEGWRYEEWGSQVTVVSGDMREWKAP-EKADIIVSELLGSFGD 438 +K V AV+++ ++ R + + ++ G + E P EK D+I+SE +G F Sbjct: 69 KK--VIAVDQSEILYQAMDIIRLNKLEDTIVLIKGKIEEVSLPVEKVDVIISEWMGYFLL 126 Query: 439 NE-LSPECLDGAQHFLKDDGVSIPGEYTSYLAPISS-----------SKLYNEVRACREK 486 E + L +L G P T L +S +Y +C +K Sbjct: 127 FESMLDSVLYAKSKYLAKGGSVYPDICTISLVAVSDVSKHADRIAFWDDVYGFNMSCMKK 186 Query: 487 DRDPEAQFEMPYVVRLHNFHQLSDP--LPCFTFHHPNKDDVIDNNRYCCLQYRVDLNTVL 544 PEA E+ + + +SDP + H + D+ ++ + + + T + Sbjct: 187 AVIPEAVVEV-----VDHKTLISDPCDIKHIDCHTTSISDLEFSSDFTLRTTKTAMCTAV 241 Query: 545 HG-FAGYFNTVLYKDVTLSICPESHSPGMFSWFPILFPIKQPIPMREGDTV 594 G F YF + V S P+S W +F +++P P++ G+ + Sbjct: 242 AGYFDIYFEKNCHNRVVFSTGPQSTKT---HWKQTIFLLEKPFPVKAGEAL 289 >5JMQ-A nrPDB Length = 446 Score = 47.0 bits (110), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 64/259 (24%), Positives = 106/259 (40%), Gaps = 27/259 (10%) Query: 355 QILMVLGAGRGPLVNASLRAAKQAERKIKVYAVEKNPNAVITLEGWRYEEWGSQVTVVSG 414 ++++ +G G G + SL A A K VYAVE + A T + + +TV Sbjct: 152 KVILDVGCGTGII---SLFCAHHARPK-AVYAVEASDMAQHTSQLVLQNGFADTITVFQQ 207 Query: 415 DMREWKAPEKADIIVSELLGSFGDNELSPECLDGAQH-FLKDDGVSIPGEYTSYLAPISS 473 + + PEK D++VSE +G+ E E + A+ +LK DG+ P +L P S+ Sbjct: 208 KVEDVVLPEKVDVLVSEWMGTCLLFEFMIESILYARDTWLKGDGIIWPTTAALHLVPCSA 267 Query: 474 SKLYN----------EVRACREKDRDPEAQFEMPYVVRLHNFHQLSDPL--PCFTFHHPN 521 K Y+ E K + F P + ++ + D L PC Sbjct: 268 EKDYHSKVLFWDNAYEFNLSALKSLAIKEFFSRP---KSNHILKPEDCLSEPCTILQLDM 324 Query: 522 KDDVIDNNRYCCLQYRVDLNT--VLHGFAGYFNTVLYKDVTLSICPESHSPGMF----SW 575 + + + + R D+ LHGF +F +V ++ + + S G W Sbjct: 325 RTVQVPDLETMRGELRFDIQKAGTLHGFTAWF-SVYFQSLEEGQPQQVLSTGPLHPTTHW 383 Query: 576 FPILFPIKQPIPMREGDTV 594 LF + P+P+ GD V Sbjct: 384 KQTLFMMDDPVPVHTGDVV 402 >4M36-A nrPDB Length = 343 Score = 45.4 bits (106), Expect = 7e-05, Method: Compositional matrix adjust. Identities = 54/189 (28%), Positives = 83/189 (43%), Gaps = 26/189 (13%) Query: 357 LMVLGAGRGPLVNASLRAAKQAERKIKVYAVEKNPN-AVITLEGWRYEEWGSQVTVV--- 412 ++ +GAG G L SL AAK + V AVE + A + E R QV V+ Sbjct: 64 VLEIGAGSGLL---SLMAAKLGAKW--VVAVEGSEELAKLARENIRANNMEHQVKVLHMM 118 Query: 413 SGDMREWKAPEKADIIVSELLGS--FGDNELSPECLDGAQHFLKDDGVSIPGEYTSYLAP 470 S +++ PE D+++SE+ G+ G++ L +D LK IP T Y P Sbjct: 119 STELKSKHLPEPPDVLLSEIFGTMMLGESALD-YVVDVRNRLLKPTTKIIPQFGTQYAVP 177 Query: 471 ISSSKLYNEVRACREKDRDPEAQ----------FEMPYVVRLH--NFHQLSDPLPCF--T 516 I L+ +D D + F Y +R++ NF +LSDP+ F Sbjct: 178 IECDALHRISSVSGWRDLDLKHMMTLQDTVSIVFAKHYGIRMNSVNFRRLSDPIELFRVD 237 Query: 517 FHHPNKDDV 525 F N++D+ Sbjct: 238 FSSSNRNDI 246 >3R0Q-C nrPDB Length = 376 Score = 45.4 bits (106), Expect = 8e-05, Method: Compositional matrix adjust. Identities = 36/121 (29%), Positives = 54/121 (44%), Gaps = 6/121 (4%) Query: 355 QILMVLGAGRGPLVNASLRAAKQAERKIKVYAVEKNPNAVITLEGWRYEEWGSQVTVVSG 414 + ++ +G G G L S +A + KVYAVE A + V V+ G Sbjct: 65 KTVLDVGTGSGILAIWSAQAGAR-----KVYAVEATKMADHARALVKANNLDHIVEVIEG 119 Query: 415 DMREWKAPEKADIIVSELLGSFGDNE-LSPECLDGAQHFLKDDGVSIPGEYTSYLAPISS 473 + + PEK D+I+SE +G F E + + +LK GV P +LAPI S Sbjct: 120 SVEDISLPEKVDVIISEWMGYFLLRESMFDSVISARDRWLKPTGVMYPSHARMWLAPIKS 179 Query: 474 S 474 + Sbjct: 180 N 180 >4RYL-A nrPDB Length = 340 Score = 44.7 bits (104), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 65/291 (22%), Positives = 119/291 (40%), Gaps = 37/291 (12%) Query: 320 YEVFEKDPVKYSQYQQAVYKCLLDRVPEEEKETNIQILMVLGAGRGPLVNASLRAAKQAE 379 +E KD ++ Y+ +Y+ P K+ ++++ +G G G L S+ AAK Sbjct: 39 HEEMLKDKIRTESYRDFIYQN-----PHIFKD---KVVLDVGCGTGIL---SMFAAKAGA 87 Query: 380 RKIKVYAVEKNPNAVITLEGWRYEEWGSQVTVVSGDMREWKAP-EKADIIVSELLGSFGD 438 +K V V+++ ++ R + +T++ G + E P EK D+I+SE +G F Sbjct: 88 KK--VLGVDQSEILYQAMDIIRLNKLEDTITLIKGKIEEVHLPVEKVDVIISEWMGYFLL 145 Query: 439 NE-LSPECLDGAQHFLKDDGVSIPGEYTSYLAPISS-----------SKLYNEVRACREK 486 E + L +L G P T L +S +Y +C +K Sbjct: 146 FESMLDSVLYAKNKYLAKGGSVYPDICTISLVAVSDVNKHADRIAFWDDVYGFKMSCMKK 205 Query: 487 DRDPEAQFEMPYVVRLHNFHQLSDP--LPCFTFHHPNKDDVIDNNRYCCLQYRVDLNTVL 544 PEA E+ L +S+P + H + D+ ++ + R + T + Sbjct: 206 AVIPEAVVEV-----LDPKTLISEPCGIKHIDCHTTSISDLEFSSDFTLKITRTSMCTAI 260 Query: 545 HG-FAGYFNTVLYKDVTLSICPESHSPGMFSWFPILFPIKQPIPMREGDTV 594 G F YF + V S P+S W +F +++P ++ G+ + Sbjct: 261 AGYFDIYFEKNCHNRVVFSTGPQSTKT---HWKQTVFLLEKPFSVKAGEAL 308 >1G6Q-1 nrPDB Length = 328 Score = 44.7 bits (104), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 58/253 (22%), Positives = 101/253 (39%), Gaps = 34/253 (13%) Query: 355 QILMVLGAGRGPLVNASLRAAKQAERKIKVYAVEKNPNAVITLEGWRYEEWGSQVTVVSG 414 +I++ +G G G L S+ AAK + V V+ + + E + ++T++ G Sbjct: 40 KIVLDVGCGTGIL---SMFAAKHGAKH--VIGVDMSSIIEMAKELVELNGFSDKITLLRG 94 Query: 415 DMREWKAP-EKADIIVSELLGSFGDNE-LSPECLDGAQHFLKDDGVSIPGEYTSYLAPIS 472 + + P K DII+SE +G F E + L H+L + G+ P + + +LA + Sbjct: 95 KLEDVHLPFPKVDIIISEWMGYFLLYESMMDTVLYARDHYLVEGGLIFPDKCSIHLAGLE 154 Query: 473 SSKLYNEVRACREKDRDPEAQFEMPYVVRLHNFHQLSDPLPCFTFHHPNKDDVIDNNRYC 532 S+ +E ++ Y ++ F P H P D V NN Sbjct: 155 DSQYKDE---------------KLNYWQDVYGFDY--SPFVPLVLHEPIVDTVERNNVNT 197 Query: 533 CLQYRV--DLNTVLHGFAGYFNTVLYKDVTLSICPESHSPGMFSWFPILFPI---KQPIP 587 + DLNTV + + L+ + G+ +WF I+FP K+P+ Sbjct: 198 TSDKLIEFDLNTV-----KISDLAFKSNFKLTAKRQDMINGIVTWFDIVFPAPKGKRPVE 252 Query: 588 MREGDTVCVRFWR 600 G W+ Sbjct: 253 FSTGPHAPYTHWK 265 >3X0D-A nrPDB Length = 655 Score = 44.7 bits (104), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 51/205 (24%), Positives = 87/205 (42%), Gaps = 19/205 (9%) Query: 336 AVYKCLLDRVPEEEKETNIQILMVLGAGRGPLVNASLRAAKQAERKIKVYAVEKNPNAVI 395 A K + E + + +L + G G G L SL AA++ K+ V K P Sbjct: 56 AGLKTTIAEKKHENTDGKVHVLDI-GTGTGLL---SLMAAREGADKVTALEVFK-PMGDC 110 Query: 396 TLEGWRYEEWGSQVTVVSGDMREWK--APEKADIIVSELLGSFGDNELSPECLDGAQHFL 453 W ++TV+S + +ADIIV+E+ + E + A L Sbjct: 111 ARHITSNSPWSDKITVISERSTDVSQIGGSRADIIVAEVFDTELIGEGALRTFKEALERL 170 Query: 454 KDDGVSI-PGEYTSYLAPISSS--KLYNEV-RACREKDRDP-------EAQFEMPYV-VR 501 G + P Y+ P+ S K++N++ R EKD +P A F++ ++ Sbjct: 171 AKPGCRVVPSTGNVYIVPVESHLLKMFNDIPRLNGEKDEEPLGRCSGTAAVFDVQLSEMK 230 Query: 502 LHNFHQLSDPLPCFTFHHPNKDDVI 526 H F +LS+P+ F F +++ +I Sbjct: 231 THEFRELSEPIVAFKFDFEHEEKII 255 >5EKU-A nrPDB Length = 390 Score = 44.7 bits (104), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 54/189 (28%), Positives = 83/189 (43%), Gaps = 26/189 (13%) Query: 357 LMVLGAGRGPLVNASLRAAKQAERKIKVYAVEKNPN-AVITLEGWRYEEWGSQVTVV--- 412 ++ +GAG G L SL AAK + V AVE + A + E R QV V+ Sbjct: 99 VLEIGAGSGLL---SLMAAKLGAKW--VVAVEGSEELAKLARENIRANNMEHQVKVLHMM 153 Query: 413 SGDMREWKAPEKADIIVSELLGS--FGDNELSPECLDGAQHFLKDDGVSIPGEYTSYLAP 470 S +++ PE D+++SE+ G+ G++ L +D LK IP T Y P Sbjct: 154 STELKPKHLPEPPDVLLSEIFGTMMLGESALD-YVVDVRNRLLKPTTKIIPQFGTQYAVP 212 Query: 471 ISSSKLYNEVRACREKDRDPEAQ----------FEMPYVVRLH--NFHQLSDPLPCF--T 516 I L+ +D D + F Y +R++ NF +LSDP+ F Sbjct: 213 IECDALHRISSVSGWRDLDLKHMMTLQDTVSIVFAKHYGIRMNSVNFRRLSDPIELFRVD 272 Query: 517 FHHPNKDDV 525 F N++D+ Sbjct: 273 FSSSNRNDI 281 >3Q7E-A nrPDB Length = 349 Score = 42.0 bits (97), Expect = 7e-04, Method: Compositional matrix adjust. Identities = 50/191 (26%), Positives = 89/191 (46%), Gaps = 26/191 (13%) Query: 284 SQNSPPPNAYEMFAKGYEDYLQSPLQPLMDNLESQTYEVFEKDPVKYSQYQQAVYKCLLD 343 +++S PNA +M +K Y Y S +E KD V+ Y+ +++ + Sbjct: 14 AESSEKPNAEDMTSKDY--YFDSYAH-------FGIHEELLKDEVRTLTYRNSMFH---N 61 Query: 344 RVPEEEKETNIQILMVLGAGRGPLVNASLRAAKQAERKIKVYAVEKNPNAVITLEGWRYE 403 R ++K +++ +G+G G L + AAK RK V +E + + ++ + Sbjct: 62 RHLFKDK-----VVLDVGSGTGIL---CMFAAKAGARK--VIGIECSSISDYAVKIVKAN 111 Query: 404 EWGSQVTVVSGDMREWKAP-EKADIIVSELLGS--FGDNELSPECLDGAQHFLKDDGVSI 460 + VT++ G + E + P EK DII+SE +G F ++ L+ L +L DG+ Sbjct: 112 KLDHVVTIIKGKVEEVELPVEKVDIIISEWMGYCLFYESMLNT-VLHARDKWLAPDGLIF 170 Query: 461 PGEYTSYLAPI 471 P T Y+ I Sbjct: 171 PDRATLYVTAI 181 >5LV5-A nrPDB Length = 403 Score = 41.2 bits (95), Expect = 0.001, Method: Compositional matrix adjust. Identities = 36/123 (29%), Positives = 57/123 (46%), Gaps = 6/123 (4%) Query: 355 QILMVLGAGRGPLVNASLRAAKQAERKIKVYAVEKNPNAVITLEGWRYEEWGSQVTVVSG 414 + ++ +GAG G L S+ A+ R+ VYAVE + E R +V V+ G Sbjct: 112 KTVLDVGAGTGIL---SIFCAQAGARR--VYAVEASAIWQQAREVVRLNGLEDRVHVLPG 166 Query: 415 DMREWKAPEKADIIVSELLG-SFGDNELSPECLDGAQHFLKDDGVSIPGEYTSYLAPISS 473 + + PE+ D IVSE +G + L +LK+ G+ +P ++APIS Sbjct: 167 PVETVELPERVDAIVSEWMGYGLLHESMLSSVLHARTKWLKEGGLLLPASAELFVAPISD 226 Query: 474 SKL 476 L Sbjct: 227 QML 229 >5EGS-A nrPDB Length = 376 Score = 40.4 bits (93), Expect = 0.002, Method: Compositional matrix adjust. Identities = 35/123 (28%), Positives = 57/123 (46%), Gaps = 6/123 (4%) Query: 355 QILMVLGAGRGPLVNASLRAAKQAERKIKVYAVEKNPNAVITLEGWRYEEWGSQVTVVSG 414 + ++ +GAG G L S+ A+ R+ VYAVE + E R+ +V V+ G Sbjct: 85 KTVLDVGAGTGIL---SIFCAQAGARR--VYAVEASAIWQQAREVVRFNGLEDRVHVLPG 139 Query: 415 DMREWKAPEKADIIVSELLG-SFGDNELSPECLDGAQHFLKDDGVSIPGEYTSYLAPISS 473 + + PE+ D IVSE +G + L +LK+ G+ +P ++ PIS Sbjct: 140 PVETVELPEQVDAIVSEWMGYGLLHESMLSSVLHARTKWLKEGGLLLPASAELFIVPISD 199 Query: 474 SKL 476 L Sbjct: 200 QML 202 >5FUB-A nrPDB Length = 337 Score = 37.4 bits (85), Expect = 0.022, Method: Compositional matrix adjust. Identities = 63/268 (23%), Positives = 98/268 (36%), Gaps = 45/268 (16%) Query: 355 QILMVLGAGRGPLVNASLRAAKQAERKIKVYAVEKNPNAVITLEGWRYEEWGSQVTVVSG 414 ++++ LG G G + AK A VYAVE + A T E + VTV Sbjct: 46 KVVLDLGCGTGVISLFCALLAKPA----GVYAVEASSMAEHTEELVKQNGCDGVVTVFQE 101 Query: 415 DMREWKAPEKADIIVSELLGSFGDNELSPE-CLDGAQHFLKDDGVSIPGEYTSYLAPISS 473 P K D++VSE +G+ E E L +LK G+ P + P + Sbjct: 102 RAENLTLPTKVDVLVSEWMGNCLLFEYMLESVLLARDRWLKKGGMMWPSSACLTIVPCQA 161 Query: 474 SKLYNEVRACREKDRDPEAQFEMPYVVRLHNFHQLSD----PLPCFTFHHPNKD------ 523 Y R +E PY + L+ P F+ H +D Sbjct: 162 FSDY----------RQKVEFWENPYGLNFSYLQSLAQKEFLSKPKFSHHLQPEDCLSTPA 211 Query: 524 DVIDNNRYCC-----------LQYRVDLNTVLHGFAGYFNT---VLYKD---VTLSICPE 566 DVI + + V+ + + HGF +F+ L +D + L+ P Sbjct: 212 DVITLDMVTIQVSDLERLKGEFTFTVEKSGMFHGFTVWFSAHFQCLEEDGPSIELNTGPY 271 Query: 567 SHSPGMFSWFPILFPIKQPIPMREGDTV 594 S + W LF + P+ + EGD + Sbjct: 272 SE---ITHWKQTLFMLDAPVSVEEGDII 296 >1RF6-A nrPDB Length = 427 Score = 34.3 bits (77), Expect = 0.15, Method: Compositional matrix adjust. Identities = 33/115 (28%), Positives = 49/115 (42%), Gaps = 21/115 (18%) Query: 378 AERKIKVYAVEKNPNAVITLE-----GWRYEEWGSQVTVVSGDMREWKAPEKA------- 425 AE + KVY + + + + T++ G E+ +TV M KAP+ A Sbjct: 33 AEGETKVYDILRGEDVLSTMQVFRDLGVEIEDKDGVITVQGVGMAGLKAPQNALNMGNSG 92 Query: 426 ---DIIVSELLGS------FGDNELSPECLDGAQHFLKDDGVSIPGEYTSYLAPI 471 +I L G+ FGD+ LS +D LK GVSI G+ L P+ Sbjct: 93 TSIRLISGVLAGADFEVEMFGDDSLSKRPMDRVTLPLKKMGVSISGQTERDLPPL 147 >4KNH-A nrPDB Length = 961 Score = 33.9 bits (76), Expect = 0.20, Method: Compositional matrix adjust. Identities = 31/124 (25%), Positives = 56/124 (45%), Gaps = 20/124 (16%) Query: 382 IKVYAVEKNPNAVITLEGWRYEEWGSQVTVVSGDMREWKAPEKADIIVS---ELLGSFGD 438 I YA E P+A ++ W + ++G + +W + + +VS E+L D Sbjct: 473 IISYAYEGRPDAAMSF-------WEDPDSNLAGFL-QWASRRASTPLVSAFCEMLRCLAD 524 Query: 439 NELSPECLDGAQHFLKDDGVSIPGEYTSYLAPISSSKLYNEV-----RACREKDRDPEAQ 493 NE EC A +FL D+G G+ + ++ S+++ E+ + C E+ P+A Sbjct: 525 NE---ECATAAHNFLLDEGHQASGKMKRSQS-LTWSQIFKELEYFTTKVCSERPNPPQAS 580 Query: 494 FEMP 497 P Sbjct: 581 MHRP 584 >5DST-A nrPDB Length = 332 Score = 33.9 bits (76), Expect = 0.24, Method: Compositional matrix adjust. Identities = 31/120 (25%), Positives = 60/120 (50%), Gaps = 9/120 (7%) Query: 355 QILMVLGAGRGPLVNASLRAAKQAERKIKVYAVEKNPNAVITLEGWRYEEWGSQVTVVSG 414 ++++ +G+G G L S+ AAK +K V+ +E + + + + + + +T+ G Sbjct: 51 KVVLDVGSGTGIL---SMFAAKAGAKK--VFGIECSSISDYSEKIIKANHLDNIITIFKG 105 Query: 415 DMREWKAP-EKADIIVSELLGS--FGDNELSPECLDGAQHFLKDDGVSIPGEYTSYLAPI 471 + E + P EK DII+SE +G F ++ L+ + +LK G+ P Y+ I Sbjct: 106 KVEEVELPVEKVDIIISEWMGYCLFYESMLNT-VIFARDKWLKPGGLMFPDRAALYVVAI 164 >2ICS-A nrPDB Length = 379 Score = 33.9 bits (76), Expect = 0.24, Method: Compositional matrix adjust. Identities = 18/48 (37%), Positives = 27/48 (56%) Query: 194 YNKKIALAIEIGADLPSGHVIDRWLGEPIKAAFLPTSIFLTNKKGFPV 241 YNK + I G D + HV + L E +KAA + T I++ N++ PV Sbjct: 236 YNKGVVFDIGHGTDSFNFHVAETALREGMKAASISTDIYIRNRENGPV 283 >3A27-A nrPDB Length = 272 Score = 32.0 bits (71), Expect = 0.93, Method: Compositional matrix adjust. Identities = 30/101 (29%), Positives = 45/101 (44%), Gaps = 12/101 (11%) Query: 384 VYAVEKNPNAVITL-EGWRYEEWGSQVTVVSGDMREWKAPEKADIIVSELLGSFGDNELS 442 VYA+EKNP A L E + + + + +++ D R+ + + AD ++ G + Sbjct: 146 VYAIEKNPTAYHYLCENIKLNKLNNVIPILA-DNRDVELKDVADRVI------MGYVHKT 198 Query: 443 PECLDGAQHFLKDDGV----SIPGEYTSYLAPISSSKLYNE 479 + LD FLKD GV E Y PI K Y E Sbjct: 199 HKFLDKTFEFLKDRGVIHYHETVAEKIMYERPIERLKFYAE 239 >1L3B-A nrPDB Length = 192 Score = 31.2 bits (69), Expect = 1.5, Method: Composition-based stats. Identities = 23/66 (34%), Positives = 35/66 (53%), Gaps = 10/66 (15%) Query: 378 AERKIKVYAVEKNPNAVITLE-GWRYEEWGSQVTVVSGDMREWKAPEK----ADIIVSEL 432 A R +VYA+++NP A+ T E + G VT++ GD APE DI ++ + Sbjct: 52 AGRVRRVYAIDRNPEAISTTEMNLQRHGLGDNVTLMEGD-----APEALCKIPDIDIAVV 106 Query: 433 LGSFGD 438 GS G+ Sbjct: 107 GGSGGE 112 >1R19-A nrPDB Length = 343 Score = 30.8 bits (68), Expect = 1.7, Method: Compositional matrix adjust. Identities = 19/66 (28%), Positives = 30/66 (45%), Gaps = 9/66 (13%) Query: 504 NFHQLSDP--LPCFTFHHPNKDDVIDNNRYCCLQYRVDLNTVLHGFAGYFNTVLYKDVTL 561 NF + P + + + PNKDD Y +Q V + T ++ + G F T Y D T+ Sbjct: 274 NFGNIDSPYIIKVISKYDPNKDD------YTTIQQTVTMQTTINEYTGEFRTASY-DNTI 326 Query: 562 SICPES 567 + S Sbjct: 327 AFSTSS 332 >4E9V-A nrPDB Length = 339 Score = 30.0 bits (66), Expect = 3.3, Method: Compositional matrix adjust. Identities = 10/25 (40%), Positives = 17/25 (68%) Query: 580 FPIKQPIPMREGDTVCVRFWRCNNG 604 FP+ QP+ +++GD V +RF+ G Sbjct: 175 FPLTQPLRVKKGDVVKIRFFGAGGG 199 >6CU3-A nrPDB Length = 336 Score = 29.3 bits (64), Expect = 4.9, Method: Compositional matrix adjust. Identities = 26/126 (20%), Positives = 54/126 (42%), Gaps = 10/126 (7%) Query: 355 QILMVLGAGRGPLVNASLRAAKQAERKIKVYAVEKNPNAVITLEGWRYEEWGSQVTVVSG 414 ++++ +G G G L + +A + I + + +++ G+ + + ++ G Sbjct: 53 KVVLDIGCGTGILCLFAAKAGAKRVIGIDMSDIIDKARQIVSDNGYSH-----VIELIKG 107 Query: 415 DMREWK----APEKADIIVSELLGSFGDNE-LSPECLDGAQHFLKDDGVSIPGEYTSYLA 469 + + EK DII+SE +G F E + L +L+ G P + T Y+ Sbjct: 108 KVEDIAQLPFGIEKVDIIISEWMGYFLLYESMLQTVLSARDRWLRPGGYLFPDKCTMYIC 167 Query: 470 PISSSK 475 I S+ Sbjct: 168 GIEDSE 173 >5MTZ-A nrPDB Length = 874 Score = 29.3 bits (64), Expect = 5.5, Method: Compositional matrix adjust. Identities = 41/167 (24%), Positives = 67/167 (40%), Gaps = 31/167 (18%) Query: 31 QGFDFLCMPIFHPRFKREFYKEPAKSRPGPQTRSDLLL----SGRDWNTLIVGKLSDWIK 86 Q F F +PI HP T+ LLL G + +G+ S Sbjct: 34 QEFMFTFIPITHPT---------------SDTKHPLLLVQSAHGEKYFFGKIGEGSQRSL 78 Query: 87 TDSEVSRIRKTSEAAMQQELNFSAYLGLPAFLIPLKQEDNSNLSRLLINHIHVGHHSTMF 146 T++++ RI K + + ELN+S GLP ++ + + SNL N I ST Sbjct: 79 TENKI-RISKLKDIFLTGELNWSDIGGLPGMILTIADQGKSNLVLHYGNDILNYIVST-- 135 Query: 147 WMRVPLMAPNDLRDDLIENEPI---------SLSEEDNSGEERTWIW 184 W DL D +++++ + S + N GE+R ++ Sbjct: 136 WRYFVFRFGIDLNDHIMKDKEVYKDKIIAVKSFNVLKNGGEDRLGVF 182 >6GWU-A nrPDB Length = 208 Score = 29.3 bits (64), Expect = 6.0, Method: Compositional matrix adjust. Identities = 16/54 (29%), Positives = 30/54 (55%), Gaps = 2/54 (3%) Query: 372 LRAAKQAERKI--KVYAVEKNPNAVITLEGWRYEEWGSQVTVVSGDMREWKAPE 423 L+A K AE + V A++++P+A + L+ E WG V +G + + + P+ Sbjct: 152 LKAKKLAELNVISSVTALKRHPSASVALKKNEIEVWGMLYDVATGYLSQVEIPQ 205 >1M4N-A nrPDB Length = 435 Score = 28.9 bits (63), Expect = 6.2, Method: Compositional matrix adjust. Identities = 14/44 (31%), Positives = 20/44 (45%) Query: 74 NTLIVGKLSDWIKTDSEVSRIRKTSEAAMQQELNFSAYLGLPAF 117 N L L W+ + E + +K E+ + F Y GLPAF Sbjct: 48 NQLCFDLLESWLAKNPEAAAFKKNGESIFAELALFQDYHGLPAF 91 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 4G56-A nrPDB 1067 0.0 5FA5-A nrPDB 1037 0.0 3UA4-A nrPDB 690 0.0 4RYL-A nrPDB 286 2e-77 1F3L-A nrPDB 284 7e-77 1G6Q-1 nrPDB 259 3e-69 5JMQ-A nrPDB 255 5e-68 3Q7E-A nrPDB 238 7e-63 3B3J-A nrPDB 201 9e-52 5IS8-A nrPDB 200 1e-51 4IKP-A nrPDB 200 1e-51 3R0Q-C nrPDB 187 1e-47 5LV5-A nrPDB 187 1e-47 3X0D-A nrPDB 177 1e-44 4M36-A nrPDB 165 5e-41 5EKU-A nrPDB 164 1e-40 Sequences not found previously or not previously below threshold: 5DST-A nrPDB 216 2e-56 6CU3-A nrPDB 187 1e-47 5EGS-A nrPDB 183 2e-46 5FUB-A nrPDB 183 2e-46 4LWO-B nrPDB 121 8e-28 6OGN-A nrPDB 93 4e-19 1L3B-A nrPDB 47 2e-05 4FS8-A nrPDB 42 8e-04 4PNE-A nrPDB 42 8e-04 3D2L-A nrPDB 42 8e-04 6GKZ-A nrPDB 42 0.001 5Z9O-A nrPDB 41 0.002 1WY7-A nrPDB 39 0.005 2IP2-A nrPDB 38 0.012 2ZZN-A nrPDB 37 0.028 5FAD-A nrPDB 36 0.065 5I2H-A nrPDB 34 0.16 1DUS-A nrPDB 34 0.25 4WXH-A nrPDB 34 0.27 2XVM-A nrPDB 34 0.27 3CJR-A nrPDB 33 0.46 5WP4-A nrPDB 32 0.59 2I6G-A nrPDB 32 0.67 3GRV-A nrPDB 32 0.69 3FYD-A nrPDB 32 0.69 5LNK-k nrPDB 32 0.73 2Z4T-A nrPDB 32 0.77 6HV9-A nrPDB 31 1.2 6C5B-A nrPDB 31 1.7 2ICS-A nrPDB 31 2.1 2PJD-A nrPDB 30 2.8 5ME5-A nrPDB 30 3.7 4KRG-A nrPDB 29 9.4 >4G56-A nrPDB Length = 657 Score = 1067 bits (2758), Expect = 0.0, Method: Composition-based stats. Identities = 632/632 (100%), Positives = 632/632 (100%) Query: 2 AAGDGGRVSSGRDVACVTEVADTLGAMANQGFDFLCMPIFHPRFKREFYKEPAKSRPGPQ 61 AAGDGGRVSSGRDVACVTEVADTLGAMANQGFDFLCMPIFHPRFKREFYKEPAKSRPGPQ Sbjct: 26 AAGDGGRVSSGRDVACVTEVADTLGAMANQGFDFLCMPIFHPRFKREFYKEPAKSRPGPQ 85 Query: 62 TRSDLLLSGRDWNTLIVGKLSDWIKTDSEVSRIRKTSEAAMQQELNFSAYLGLPAFLIPL 121 TRSDLLLSGRDWNTLIVGKLSDWIKTDSEVSRIRKTSEAAMQQELNFSAYLGLPAFLIPL Sbjct: 86 TRSDLLLSGRDWNTLIVGKLSDWIKTDSEVSRIRKTSEAAMQQELNFSAYLGLPAFLIPL 145 Query: 122 KQEDNSNLSRLLINHIHVGHHSTMFWMRVPLMAPNDLRDDLIENEPISLSEEDNSGEERT 181 KQEDNSNLSRLLINHIHVGHHSTMFWMRVPLMAPNDLRDDLIENEPISLSEEDNSGEERT Sbjct: 146 KQEDNSNLSRLLINHIHVGHHSTMFWMRVPLMAPNDLRDDLIENEPISLSEEDNSGEERT 205 Query: 182 WIWWHNFRSLCDYNKKIALAIEIGADLPSGHVIDRWLGEPIKAAFLPTSIFLTNKKGFPV 241 WIWWHNFRSLCDYNKKIALAIEIGADLPSGHVIDRWLGEPIKAAFLPTSIFLTNKKGFPV Sbjct: 206 WIWWHNFRSLCDYNKKIALAIEIGADLPSGHVIDRWLGEPIKAAFLPTSIFLTNKKGFPV 265 Query: 242 LTKVHQRLIFKLFKLEVQFVISGSHHHSEKDLCSYLQYLEYLSQNSPPPNAYEMFAKGYE 301 LTKVHQRLIFKLFKLEVQFVISGSHHHSEKDLCSYLQYLEYLSQNSPPPNAYEMFAKGYE Sbjct: 266 LTKVHQRLIFKLFKLEVQFVISGSHHHSEKDLCSYLQYLEYLSQNSPPPNAYEMFAKGYE 325 Query: 302 DYLQSPLQPLMDNLESQTYEVFEKDPVKYSQYQQAVYKCLLDRVPEEEKETNIQILMVLG 361 DYLQSPLQPLMDNLESQTYEVFEKDPVKYSQYQQAVYKCLLDRVPEEEKETNIQILMVLG Sbjct: 326 DYLQSPLQPLMDNLESQTYEVFEKDPVKYSQYQQAVYKCLLDRVPEEEKETNIQILMVLG 385 Query: 362 AGRGPLVNASLRAAKQAERKIKVYAVEKNPNAVITLEGWRYEEWGSQVTVVSGDMREWKA 421 AGRGPLVNASLRAAKQAERKIKVYAVEKNPNAVITLEGWRYEEWGSQVTVVSGDMREWKA Sbjct: 386 AGRGPLVNASLRAAKQAERKIKVYAVEKNPNAVITLEGWRYEEWGSQVTVVSGDMREWKA 445 Query: 422 PEKADIIVSELLGSFGDNELSPECLDGAQHFLKDDGVSIPGEYTSYLAPISSSKLYNEVR 481 PEKADIIVSELLGSFGDNELSPECLDGAQHFLKDDGVSIPGEYTSYLAPISSSKLYNEVR Sbjct: 446 PEKADIIVSELLGSFGDNELSPECLDGAQHFLKDDGVSIPGEYTSYLAPISSSKLYNEVR 505 Query: 482 ACREKDRDPEAQFEMPYVVRLHNFHQLSDPLPCFTFHHPNKDDVIDNNRYCCLQYRVDLN 541 ACREKDRDPEAQFEMPYVVRLHNFHQLSDPLPCFTFHHPNKDDVIDNNRYCCLQYRVDLN Sbjct: 506 ACREKDRDPEAQFEMPYVVRLHNFHQLSDPLPCFTFHHPNKDDVIDNNRYCCLQYRVDLN 565 Query: 542 TVLHGFAGYFNTVLYKDVTLSICPESHSPGMFSWFPILFPIKQPIPMREGDTVCVRFWRC 601 TVLHGFAGYFNTVLYKDVTLSICPESHSPGMFSWFPILFPIKQPIPMREGDTVCVRFWRC Sbjct: 566 TVLHGFAGYFNTVLYKDVTLSICPESHSPGMFSWFPILFPIKQPIPMREGDTVCVRFWRC 625 Query: 602 NNGKKVWYEWAVTSPVCSAIHNPTGRSYTIGL 633 NNGKKVWYEWAVTSPVCSAIHNPTGRSYTIGL Sbjct: 626 NNGKKVWYEWAVTSPVCSAIHNPTGRSYTIGL 657 >5FA5-A nrPDB Length = 650 Score = 1037 bits (2682), Expect = 0.0, Method: Composition-based stats. Identities = 527/627 (84%), Positives = 587/627 (93%), Gaps = 1/627 (0%) Query: 7 GRVSSGRDVACVTEVADTLGAMANQGFDFLCMPIFHPRFKREFYKEPAKSRPGPQTRSDL 66 RVSSGRD+ CV E+ADTLGA+A QGFDFLCMP+FHPRFKREF +EPAK+RPGPQTRSDL Sbjct: 25 SRVSSGRDLNCVPEIADTLGAVAKQGFDFLCMPVFHPRFKREFIQEPAKNRPGPQTRSDL 84 Query: 67 LLSGRDWNTLIVGKLSDWIKTDSEVSRIRKTSEAAMQQELNFSAYLGLPAFLIPLKQEDN 126 LLSGRDWNTLIVGKLS WI+ DS+V +IR+ SEAAM QELNF AYLGLPAFL+PL QEDN Sbjct: 85 LLSGRDWNTLIVGKLSPWIRPDSKVEKIRRNSEAAMLQELNFGAYLGLPAFLLPLNQEDN 144 Query: 127 SNLSRLLINHIHVGHHSTMFWMRVPLMAPNDLRDDLIENEPISLSEEDNSGEERTWIWWH 186 +NL+R+L NHIH GHHS+MFWMRVPL+AP DLRDD+IEN P + +EE SGEE+TW+WWH Sbjct: 145 TNLARVLTNHIHTGHHSSMFWMRVPLVAPEDLRDDIIENAPTTHTEE-YSGEEKTWMWWH 203 Query: 187 NFRSLCDYNKKIALAIEIGADLPSGHVIDRWLGEPIKAAFLPTSIFLTNKKGFPVLTKVH 246 NFR+LCDY+K+IA+A+EIGADLPS HVIDRWLGEPIKAA LPTSIFLTNKKGFPVL+K+H Sbjct: 204 NFRTLCDYSKRIAVALEIGADLPSNHVIDRWLGEPIKAAILPTSIFLTNKKGFPVLSKMH 263 Query: 247 QRLIFKLFKLEVQFVISGSHHHSEKDLCSYLQYLEYLSQNSPPPNAYEMFAKGYEDYLQS 306 QRLIF+L KLEVQF+I+G++HHSEK+ CSYLQYLEYLSQN PPPNAYE+FAKGYEDYLQS Sbjct: 264 QRLIFRLLKLEVQFIITGTNHHSEKEFCSYLQYLEYLSQNRPPPNAYELFAKGYEDYLQS 323 Query: 307 PLQPLMDNLESQTYEVFEKDPVKYSQYQQAVYKCLLDRVPEEEKETNIQILMVLGAGRGP 366 PLQPLMDNLESQTYEVFEKDP+KYSQYQQA+YKCLLDRVPEEEK+TN+Q+LMVLGAGRGP Sbjct: 324 PLQPLMDNLESQTYEVFEKDPIKYSQYQQAIYKCLLDRVPEEEKDTNVQVLMVLGAGRGP 383 Query: 367 LVNASLRAAKQAERKIKVYAVEKNPNAVITLEGWRYEEWGSQVTVVSGDMREWKAPEKAD 426 LVNASLRAAKQA+R+IK+YAVEKNPNAV+TLE W++EEWGSQVTVVS DMREW APEKAD Sbjct: 384 LVNASLRAAKQADRRIKLYAVEKNPNAVVTLENWQFEEWGSQVTVVSSDMREWVAPEKAD 443 Query: 427 IIVSELLGSFGDNELSPECLDGAQHFLKDDGVSIPGEYTSYLAPISSSKLYNEVRACREK 486 IIVSELLGSF DNELSPECLDGAQHFLKDDGVSIPGEYTS+LAPISSSKLYNEVRACREK Sbjct: 444 IIVSELLGSFADNELSPECLDGAQHFLKDDGVSIPGEYTSFLAPISSSKLYNEVRACREK 503 Query: 487 DRDPEAQFEMPYVVRLHNFHQLSDPLPCFTFHHPNKDDVIDNNRYCCLQYRVDLNTVLHG 546 DRDPEAQFEMPYVVRLHNFHQLS P PCFTF HPN+D +IDNNRYC L++ V++NTVLHG Sbjct: 504 DRDPEAQFEMPYVVRLHNFHQLSAPQPCFTFSHPNRDPMIDNNRYCTLEFPVEVNTVLHG 563 Query: 547 FAGYFNTVLYKDVTLSICPESHSPGMFSWFPILFPIKQPIPMREGDTVCVRFWRCNNGKK 606 FAGYF TVLY+D+TLSI PE+HSPGMFSWFPILFPIKQPI +REG T+CVRFWRC+N KK Sbjct: 564 FAGYFETVLYQDITLSIRPETHSPGMFSWFPILFPIKQPITVREGQTICVRFWRCSNSKK 623 Query: 607 VWYEWAVTSPVCSAIHNPTGRSYTIGL 633 VWYEWAVT+PVCSAIHNPTGRSYTIGL Sbjct: 624 VWYEWAVTAPVCSAIHNPTGRSYTIGL 650 >3UA4-A nrPDB Length = 745 Score = 690 bits (1779), Expect = 0.0, Method: Composition-based stats. Identities = 207/647 (31%), Positives = 310/647 (47%), Gaps = 91/647 (14%) Query: 53 PAKSRPGPQTRSDLLLSGRDWNTLIVGKLSDWIKTDSEVSRIRKTSEAAMQQELNFSAYL 112 P P Q R+DL W + +VGK+S WI DS SE + +EL++ YL Sbjct: 108 PVIDLPDVQLRNDL------WESYVVGKISPWIDCDSSDPAFASLSEEHLLKELSYICYL 161 Query: 113 GLPAFLIPLKQEDNSNLSRLLINHIHVGHHSTMFWMRVPLMAPNDLRDDLIENEPISLSE 172 GL I L + + + +L I + W+++P D E + L Sbjct: 162 GLQTMAIELTRISSPRTAAILKKWIWTRNSRFTVWVQLPSAIEKCKDYDAFTIEHVDL-- 219 Query: 173 EDNSGEERTWIWWHNFRSLCDYNKKI--ALAIEIGADLPSG----HVIDRWLGEPIKAAF 226 W W +FR C + +A+ I ++LP ++DRW EP+ A Sbjct: 220 ---------WTIWADFRKNCGNFSGVYFQVALTISSELPDELTELKLVDRWKAEPLAAFV 270 Query: 227 LPTSIFLTNKKGFPVLTKVHQRLIFKLFKLEVQFVI----SGSHHHSEKDLCSYLQYLEY 282 + + +F++ + G + H L+ L+ + ++ + + ++ Y Q L + Sbjct: 271 IESGLFISGRNGEASIPSAHINLLKHLWTTDALRIVLRATTDTFKYNTSIKSEYSQALRH 330 Query: 283 LSQN----SPP-------PNAYEMFAKGYEDYLQSPLQPLMDNLESQTYEVFEKDPVKYS 331 +N S P + + + Y+D LQ+PLQPL +NL+S Y FE+D +KY Sbjct: 331 AVRNVNYRSRPDVGEGSNDSTHYLNVIEYKDVLQAPLQPLSENLDSGVYNTFEQDQIKYD 390 Query: 332 QYQQAVYKCLLDRVPEEEKETNIQILMVLGAGRGPLVNASLRAAK---------QAERKI 382 Y +AV L D + K ++ +LG GRGP+ L++ + Q K+ Sbjct: 391 VYGEAVVGALKDLGADGRKTV---VIYLLGGGRGPIGTKILKSEREYNNTFRQGQESLKV 447 Query: 383 KVYAVEKNPNAVITLEGWRYEEWGSQVTVVSGDMREW------KAPEKADIIVSELLGSF 436 K+Y VEKNPNA++TL+ W +VT++ DMR + E+ DIIVSELLGSF Sbjct: 448 KLYIVEKNPNAIVTLKYMNVRTWKRRVTIIESDMRSLPGIAKDRGFEQPDIIVSELLGSF 507 Query: 437 GDNELSPECLDGAQHFLKDDGVSIPGEYTSYLAPISSSKLYNEVRACR------------ 484 GDNELSPECLDG FLK +SIP +YTSY+ PI S+ ++ ++A Sbjct: 508 GDNELSPECLDGVTGFLKPTTISIPQKYTSYVKPIMSTHIHQTIKAQSIPYLSRAIPSHG 567 Query: 485 ----EKDRD-------PEAQ----FEMPYVVRLHNFHQLSDPL-PCFTFHHPNKDDVIDN 528 E D D P+ + YVV L + L++ P FTF HPN + N Sbjct: 568 RGEPELDEDEMWIQKYPQGHVRNNMDQIYVVYLSKYIPLAETTKPVFTFEHPNFMNS-SN 626 Query: 529 NRYCCLQYRVDLNTVLHGFAGYFNTVLYKDVTLSICPESHSPGMFSWFPILFPIKQPIPM 588 R +++ +D N L GFAGYF+ LYK V LSI P +H+PGM SWFP + P++ + + Sbjct: 627 ERSDSIEFVMDRNADLMGFAGYFDLQLYKTVMLSIEPSTHTPGMVSWFPAVIPLRDQLRV 686 Query: 589 REGDTVCVRFWRCNNGKKVWYEWAVTS------PVCSAIHNPTGRSY 629 EGD + ++ R + VWYEW V V + I NP G SY Sbjct: 687 GEGDRISLKIDRKVDNTGVWYEWHVEKKKTNGESVSTPIQNPNGESY 733 >4RYL-A nrPDB Length = 340 Score = 286 bits (731), Expect = 2e-77, Method: Composition-based stats. Identities = 68/321 (21%), Positives = 124/321 (38%), Gaps = 44/321 (13%) Query: 290 PNAYEMFAKGYEDYLQSPLQPLMDNLESQTYEVFEKDPVKYSQYQQAVYKCLLDRVPEEE 349 P ++ Y S +E KD ++ Y+ +Y+ P Sbjct: 16 PRGSDLQEDEDGVYFSSYGH-------YGIHEEMLKDKIRTESYRDFIYQN-----PHIF 63 Query: 350 KETNIQILMVLGAGRGPLVNASLRAAKQAERKIKVYAVEKNPNAVITLEGWRYEEWGSQV 409 K+ ++++ +G G G L S+ AAK +K V V+++ ++ R + + Sbjct: 64 KD---KVVLDVGCGTGIL---SMFAAKAGAKK--VLGVDQSEILYQAMDIIRLNKLEDTI 115 Query: 410 TVVSGDMREWKAP-EKADIIVSELLGSFGDNE-LSPECLDGAQHFLKDDGVSIPGEYTSY 467 T++ G + E P EK D+I+SE +G F E + L +L G P T Sbjct: 116 TLIKGKIEEVHLPVEKVDVIISEWMGYFLLFESMLDSVLYAKNKYLAKGGSVYPDICTIS 175 Query: 468 LAPISS-----------SKLYNEVRACREKDRDPEAQFEMPYVVRLHNFHQLSDP--LPC 514 L +S +Y +C +K PEA E+ L +S+P + Sbjct: 176 LVAVSDVNKHADRIAFWDDVYGFKMSCMKKAVIPEAVVEV-----LDPKTLISEPCGIKH 230 Query: 515 FTFHHPNKDDVIDNNRYCCLQYRVDLNTVLHG-FAGYFNTVLYKDVTLSICPESHSPGMF 573 H + D+ ++ + R + T + G F YF + V S P+S Sbjct: 231 IDCHTTSISDLEFSSDFTLKITRTSMCTAIAGYFDIYFEKNCHNRVVFSTGPQSTKT--- 287 Query: 574 SWFPILFPIKQPIPMREGDTV 594 W +F +++P ++ G+ + Sbjct: 288 HWKQTVFLLEKPFSVKAGEAL 308 >1F3L-A nrPDB Length = 321 Score = 284 bits (727), Expect = 7e-77, Method: Composition-based stats. Identities = 68/308 (22%), Positives = 123/308 (39%), Gaps = 44/308 (14%) Query: 303 YLQSPLQPLMDNLESQTYEVFEKDPVKYSQYQQAVYKCLLDRVPEEEKETNIQILMVLGA 362 Y S +E KD V+ Y+ +Y+ P K+ ++++ +G Sbjct: 10 YFSSYGH-------YGIHEEMLKDKVRTESYRDFIYQN-----PHIFKD---KVVLDVGC 54 Query: 363 GRGPLVNASLRAAKQAERKIKVYAVEKNPNAVITLEGWRYEEWGSQVTVVSGDMREWKAP 422 G G L S+ AAK +K V AV+++ ++ R + + ++ G + E P Sbjct: 55 GTGIL---SMFAAKAGAKK--VIAVDQSEILYQAMDIIRLNKLEDTIVLIKGKIEEVSLP 109 Query: 423 -EKADIIVSELLGSFGDNE-LSPECLDGAQHFLKDDGVSIPGEYTSYLAPISS------- 473 EK D+I+SE +G F E + L +L G P T L +S Sbjct: 110 VEKVDVIISEWMGYFLLFESMLDSVLYAKSKYLAKGGSVYPDICTISLVAVSDVSKHADR 169 Query: 474 ----SKLYNEVRACREKDRDPEAQFEMPYVVRLHNFHQLSDP--LPCFTFHHPNKDDVID 527 +Y +C +K PEA E+ + + +SDP + H + D+ Sbjct: 170 IAFWDDVYGFNMSCMKKAVIPEAVVEV-----VDHKTLISDPCDIKHIDCHTTSISDLEF 224 Query: 528 NNRYCCLQYRVDLNTVLHG-FAGYFNTVLYKDVTLSICPESHSPGMFSWFPILFPIKQPI 586 ++ + + + T + G F YF + V S P+S W +F +++P Sbjct: 225 SSDFTLRTTKTAMCTAVAGYFDIYFEKNCHNRVVFSTGPQSTKT---HWKQTIFLLEKPF 281 Query: 587 PMREGDTV 594 P++ G+ + Sbjct: 282 PVKAGEAL 289 >1G6Q-1 nrPDB Length = 328 Score = 259 bits (661), Expect = 3e-69, Method: Composition-based stats. Identities = 66/306 (21%), Positives = 115/306 (37%), Gaps = 51/306 (16%) Query: 303 YLQSPLQPLMDNLESQTYEVFEKDPVKYSQYQQAVYKCLLDRVPEEEKE-TNIQILMVLG 361 Y S +E +D V+ Y+ A+ + K+ +I++ +G Sbjct: 3 YFDSYDH-------YGIHEEMLQDTVRTLSYRNAIIQ---------NKDLFKDKIVLDVG 46 Query: 362 AGRGPLVNASLRAAKQAERKIKVYAVEKNPNAVITLEGWRYEEWGSQVTVVSGDMREWKA 421 G G L S+ AAK + V V+ + + E + ++T++ G + + Sbjct: 47 CGTGIL---SMFAAKHGAKH--VIGVDMSSIIEMAKELVELNGFSDKITLLRGKLEDVHL 101 Query: 422 P-EKADIIVSELLGSFGDNE-LSPECLDGAQHFLKDDGVSIPGEYTSYLAPISSSKLYNE 479 P K DII+SE +G F E + L H+L + G+ P + + +LA + S+ +E Sbjct: 102 PFPKVDIIISEWMGYFLLYESMMDTVLYARDHYLVEGGLIFPDKCSIHLAGLEDSQYKDE 161 Query: 480 VRACREKDRDPEAQFEMPYVVRLHNFHQLSDPLPCFTFHHPNKDDVIDNNRYCCLQYR-- 537 ++ Y ++ F P H P D V NN Sbjct: 162 ---------------KLNYWQDVYGFDY--SPFVPLVLHEPIVDTVERNNVNTTSDKLIE 204 Query: 538 VDLNTVLHGFAGYFNTVLYKDVTLSICPESHSPGMFSWFPILFPI---KQPIPMREGDTV 594 DLNTV + + L+ + G+ +WF I+FP K+P+ G Sbjct: 205 FDLNTV-----KISDLAFKSNFKLTAKRQDMINGIVTWFDIVFPAPKGKRPVEFSTGPHA 259 Query: 595 CVRFWR 600 W+ Sbjct: 260 PYTHWK 265 >5JMQ-A nrPDB Length = 446 Score = 255 bits (650), Expect = 5e-68, Method: Composition-based stats. Identities = 76/343 (22%), Positives = 128/343 (37%), Gaps = 51/343 (14%) Query: 301 EDYLQSPLQPLMDNLESQTYEVFEKDPVKYSQYQQAVYKCLLDRVPEEEKETNIQILMVL 360 E+Y S + + D + ++Y + + ++ ++++ + Sbjct: 113 EEYFDSYG-------TLKLHLEMLADQPRTTKYHSVILQN--------KESLKDKVILDV 157 Query: 361 GAGRGPLVNASLRAAKQAERKIKVYAVEKNPNAVITLEGWRYEEWGSQVTVVSGDMREWK 420 G G G + SL A A K VYAVE + A T + + +TV + + Sbjct: 158 GCGTGII---SLFCAHHARPK-AVYAVEASDMAQHTSQLVLQNGFADTITVFQQKVEDVV 213 Query: 421 APEKADIIVSELLGSFGDNELSPE-CLDGAQHFLKDDGVSIPGEYTSYLAPISSSKLYN- 478 PEK D++VSE +G+ E E L +LK DG+ P +L P S+ K Y+ Sbjct: 214 LPEKVDVLVSEWMGTCLLFEFMIESILYARDTWLKGDGIIWPTTAALHLVPCSAEKDYHS 273 Query: 479 ---------EVRACREKDRDPEAQFEMPYVVRLHNFHQLSDPL--PCFTFHHPNKDDVID 527 E K + F P + ++ + D L PC + + Sbjct: 274 KVLFWDNAYEFNLSALKSLAIKEFFSRP---KSNHILKPEDCLSEPCTILQLDMRTVQVP 330 Query: 528 NNRYCCLQYRVDLNT--VLHGFAGYFNTVLYKDVTLSICPESHSPGMF----SWFPILFP 581 + + R D+ LHGF +F +V ++ + + S G W LF Sbjct: 331 DLETMRGELRFDIQKAGTLHGFTAWF-SVYFQSLEEGQPQQVLSTGPLHPTTHWKQTLFM 389 Query: 582 IKQPIPMREGDTVCVR-------FWRCNNGKKVWYEWAVTSPV 617 + P+P+ GD V WR + V W VTS + Sbjct: 390 MDDPVPVHTGDVVTGSVVLQRNPVWRRHMS--VSLSWVVTSAL 430 >3Q7E-A nrPDB Length = 349 Score = 238 bits (606), Expect = 7e-63, Method: Composition-based stats. Identities = 72/340 (21%), Positives = 131/340 (38%), Gaps = 51/340 (15%) Query: 284 SQNSPPPNAYEMFAKGYEDYLQSPLQPLMDNLESQTYEVFEKDPVKYSQYQQAVYKCLLD 343 +++S PNA +M +K Y Y S +E KD V+ Y+ +++ Sbjct: 14 AESSEKPNAEDMTSKDY--YFDSYAH-------FGIHEELLKDEVRTLTYRNSMF----- 59 Query: 344 RVPEEEKETNIQILMVLGAGRGPLVNASLRAAKQAERKIKVYAVEKNPNAVITLEGWRYE 403 ++++ +G+G G L + AAK RK V +E + + ++ + Sbjct: 60 ---HNRHLFKDKVVLDVGSGTGIL---CMFAAKAGARK--VIGIECSSISDYAVKIVKAN 111 Query: 404 EWGSQVTVVSGDMREWKAP-EKADIIVSELLGSFGDNE-LSPECLDGAQHFLKDDGVSIP 461 + VT++ G + E + P EK DII+SE +G E + L +L DG+ P Sbjct: 112 KLDHVVTIIKGKVEEVELPVEKVDIIISEWMGYCLFYESMLNTVLHARDKWLAPDGLIFP 171 Query: 462 GEYTSYLAPISS-----------SKLYNEVRACREKDRDPEAQFEMPYVVRLHNFHQLSD 510 T Y+ I +Y +C KD + P V + +++ Sbjct: 172 DRATLYVTAIEDRQYKDYKIHWWENVYGFDMSCI-KDVAIKE----PLVDVVDPKQLVTN 226 Query: 511 P--LPCFTFHHPNKDDVIDNNRYCCLQYRVDLNTVLHGFAGYFN---TVLYKDVTLSICP 565 + + +D+ + +C +V N +H YFN T +K S P Sbjct: 227 ACLIKEVDIYTVKVEDLTFTSPFC---LQVKRNDYVHALVAYFNIEFTRCHKRTGFSTSP 283 Query: 566 ESHSPGMFSWFPILFPIKQPIPMREGDTVCVRFWRCNNGK 605 ES W +F ++ + ++ G+ + N K Sbjct: 284 ESPYT---HWKQTVFYMEDYLTVKTGEEIFGTIGMRPNAK 320 >5DST-A nrPDB Length = 332 Score = 216 bits (550), Expect = 2e-56, Method: Composition-based stats. Identities = 64/333 (19%), Positives = 128/333 (38%), Gaps = 43/333 (12%) Query: 289 PPNAYEMFAKGYEDYLQSPLQPLMDNLESQTYEVFEKDPVKYSQYQQAVYKCLLDRVPEE 348 P + EM ++ Y Y S +E KD V+ Y+ ++Y Sbjct: 2 PLGSEEMTSRDY--YFDSYAH-------FGIHEEMLKDEVRTLTYRNSMYHN-----KHV 47 Query: 349 EKETNIQILMVLGAGRGPLVNASLRAAKQAERKIKVYAVEKNPNAVITLEGWRYEEWGSQ 408 K+ ++++ +G+G G L S+ AAK +K V+ +E + + + + + + Sbjct: 48 FKD---KVVLDVGSGTGIL---SMFAAKAGAKK--VFGIECSSISDYSEKIIKANHLDNI 99 Query: 409 VTVVSGDMREWKAP-EKADIIVSELLGSFGDNE-LSPECLDGAQHFLKDDGVSIPGEYTS 466 +T+ G + E + P EK DII+SE +G E + + +LK G+ P Sbjct: 100 ITIFKGKVEEVELPVEKVDIIISEWMGYCLFYESMLNTVIFARDKWLKPGGLMFPDRAAL 159 Query: 467 YLAPISSSKLYNEVRACREKDRDPEAQFEMPYVVRLHNFHQLSDP---------LPCFTF 517 Y+ I + Y + + ++ + V + DP + Sbjct: 160 YVVAIEDRQ-YKDFKIHWWENVYGFDMTCIRDVAMKEPLVDIVDPKQVVTNACLIKEVDI 218 Query: 518 HHPNKDDVIDNNRYCCLQYRVDLNTVLHGFAGYFN---TVLYKDVTLSICPESHSPGMFS 574 + +++ + +C ++ N +H YFN T +K + S P++ Sbjct: 219 YTVKTEELSFTSAFC---LQIQRNDYVHALVTYFNIEFTKCHKKMGFSTAPDAPYT---H 272 Query: 575 WFPILFPIKQPIPMREGDTVCVRFWRCNNGKKV 607 W +F ++ + +R G+ + N K V Sbjct: 273 WKQTVFYLEDYLTVRRGEEIYGTISMKPNAKNV 305 >3B3J-A nrPDB Length = 480 Score = 201 bits (510), Expect = 9e-52, Method: Composition-based stats. Identities = 74/349 (21%), Positives = 130/349 (37%), Gaps = 54/349 (15%) Query: 272 DLCSYLQYLEY-----LSQNSPPPNAYEMFAKGYEDYLQSPLQPLMDNLESQTYEVFEKD 326 D CS+ L+ L ++ E A Y + Q + +D Sbjct: 90 DFCSFYNILKTCRGHTLERSVFSERTEESSAVQYFQFYGYLSQ----------QQNMMQD 139 Query: 327 PVKYSQYQQAVYKCLLDRVPEEEKETNIQILMVLGAGRGPLVNASLRAAKQAERKIKVYA 386 V+ YQ+A+ + + +I++ +G G G L S AA+ RKI YA Sbjct: 140 YVRTGTYQRAILQN--------HTDFKDKIVLDVGCGSGIL---SFFAAQAGARKI--YA 186 Query: 387 VEKNPNAVITLEGWRYEEWGSQVTVVSGDMREWKAPEKADIIVSELLGSFGDNELSPECL 446 VE + A + ++ V+ G + E PE+ DII+SE +G NE E Sbjct: 187 VEASTMAQHAEVLVKSNNLTDRIVVIPGKVEEVSLPEQVDIIISEPMGYMLFNERMLESY 246 Query: 447 DGAQHFLKDDGVSIPGEYTSYLAPISSSKLYNE---------------VRACREKDRDPE 491 A+ +LK G P +LAP + +LY E V + + Sbjct: 247 LHAKKYLKPSGNMFPTIGDVHLAPFTDEQLYMEQFTKANFWYQPSFHGVDLSALRGAAVD 306 Query: 492 AQFEMPYVVRLHNFHQLSDPLPCFTFHHPNKDDVIDNNRYCCLQYRVDL--NTVLHGFAG 549 F P VV + L +T + + + + ++ + + ++HG A Sbjct: 307 EYFRQP-VVDTFDIRILMAKSVKYTVNF--LEAKEGDLHRIEIPFKFHMLHSGLVHGLAF 363 Query: 550 YFNTVLYKDVT---LSICPESHSPGMFSWFPILFPIKQPIPMREGDTVC 595 +F+ + LS P + + W+ + + P+ + GDT+ Sbjct: 364 WFDVAFIGSIMTVWLSTAP---TEPLTHWYQVRCLFQSPLFAKAGDTLS 409 >5IS8-A nrPDB Length = 381 Score = 200 bits (509), Expect = 1e-51, Method: Composition-based stats. Identities = 65/295 (22%), Positives = 116/295 (39%), Gaps = 39/295 (13%) Query: 321 EVFEKDPVKYSQYQQAVYKCLLDRVPEEEKETNIQILMVLGAGRGPLVNASLRAAKQAER 380 + +D V+ YQ+A+ + + +I++ +G G G L S AA+ R Sbjct: 35 QNMMQDYVRTGTYQRAILQN--------HTDFKDKIVLDVGCGSGIL---SFFAAQAGAR 83 Query: 381 KIKVYAVEKNPNAVITLEGWRYEEWGSQVTVVSGDMREWKAPEKADIIVSELLGSFGDNE 440 KI YAVE + A + ++ V+ G + E PE+ DII+SE +G NE Sbjct: 84 KI--YAVEASTMAQHAEVLVKSNNLTDRIVVIPGKVEEVSLPEQVDIIISEPMGYMLFNE 141 Query: 441 LSPECLDGAQHFLKDDGVSIPGEYTSYLAPISSSKLYNE---------------VRACRE 485 E A+ +LK G P +LAP + +LY E V Sbjct: 142 RMLESYLHAKKYLKPSGNMFPTIGDVHLAPFTDEQLYMEQFTKANFWYQPSFHGVDLSAL 201 Query: 486 KDRDPEAQFEMPYVVRLHNFHQLSDPLPCFTFHHPNKDDVIDNNRYCCLQYRVDL--NTV 543 + + F P VV + L +T + + + + ++ + + + Sbjct: 202 RGAAVDEYFRQP-VVDTFDIRILMAKSVKYTVNF--LEAKEGDLHRIEIPFKFHMLHSGL 258 Query: 544 LHGFAGYFNTVLYKDVT---LSICPESHSPGMFSWFPILFPIKQPIPMREGDTVC 595 +HG A +F+ + LS P + + W+ + + P+ + GDT+ Sbjct: 259 VHGLAFWFDVAFIGSIMTVWLSTAP---TEPLTHWYQVRCLFQSPLFAKAGDTLS 310 >4IKP-A nrPDB Length = 341 Score = 200 bits (509), Expect = 1e-51, Method: Composition-based stats. Identities = 65/295 (22%), Positives = 116/295 (39%), Gaps = 39/295 (13%) Query: 321 EVFEKDPVKYSQYQQAVYKCLLDRVPEEEKETNIQILMVLGAGRGPLVNASLRAAKQAER 380 + +D V+ YQ+A+ + + +I++ +G G G L S AA+ R Sbjct: 21 QNMMQDYVRTGTYQRAILQN--------HTDFKDKIVLDVGCGSGIL---SFFAAQAGAR 69 Query: 381 KIKVYAVEKNPNAVITLEGWRYEEWGSQVTVVSGDMREWKAPEKADIIVSELLGSFGDNE 440 KI YAVE + A + ++ V+ G + E PE+ DII+SE +G NE Sbjct: 70 KI--YAVEASTMAQHAEVLVKSNNLTDRIVVIPGKVEEVSLPEQVDIIISEPMGYMLFNE 127 Query: 441 LSPECLDGAQHFLKDDGVSIPGEYTSYLAPISSSKLYNE---------------VRACRE 485 E A+ +LK G P +LAP + +LY E V Sbjct: 128 RMLESYLHAKKYLKPSGNMFPTIGDVHLAPFTDEQLYMEQFTKANFWYQPSFHGVDLSAL 187 Query: 486 KDRDPEAQFEMPYVVRLHNFHQLSDPLPCFTFHHPNKDDVIDNNRYCCLQYRVDL--NTV 543 + + F P VV + L +T + + + + ++ + + + Sbjct: 188 RGAAVDEYFRQP-VVDTFDIRILMAKSVKYTVNF--LEAKEGDLHRIEIPFKFHMLHSGL 244 Query: 544 LHGFAGYFNTVLYKDVT---LSICPESHSPGMFSWFPILFPIKQPIPMREGDTVC 595 +HG A +F+ + LS P + + W+ + + P+ + GDT+ Sbjct: 245 VHGLAFWFDVAFIGSIMTVWLSTAP---TEPLTHWYQVRCLFQSPLFAKAGDTLS 296 >6CU3-A nrPDB Length = 336 Score = 187 bits (475), Expect = 1e-47, Method: Composition-based stats. Identities = 49/297 (16%), Positives = 102/297 (34%), Gaps = 39/297 (13%) Query: 317 SQTYEVFEKDPVKYSQYQQAVYKCLLDRVPEEEKETNIQILMVLGAGRGPLVNASLRAAK 376 + +E KD ++ + Y+ A+ + K+ ++++ +G G G L L AAK Sbjct: 23 TGIHEEMLKDGIRTNAYKNAILQN-----KHLFKD---KVVLDIGCGTGIL---CLFAAK 71 Query: 377 QAERKIKVYAVEKNPNAVITLEGWRYEEWGSQVTVVSGDMREW-KAP---EKADIIVSEL 432 ++ V ++ + + + + ++ G + + + P EK DII+SE Sbjct: 72 AGAKR--VIGIDMSDIIDKARQIVSDNGYSHVIELIKGKVEDIAQLPFGIEKVDIIISEW 129 Query: 433 LGSFGDNE-LSPECLDGAQHFLKDDGVSIPGEYTSYLAPISSSKLYNE----------VR 481 +G F E + L +L+ G P + T Y+ I S+ + Sbjct: 130 MGYFLLYESMLQTVLSARDRWLRPGGYLFPDKCTMYICGIEDSEYKRDKIDFWDNVYGFN 189 Query: 482 ACREKDRDPEAQFEMPYVVRLHNFHQLSDPLPCFTFHHPNKDDVIDNNRYCCLQYRVDLN 541 K P V + + ++ ++ Sbjct: 190 FSAIKADALRE----PLVDFVESQQIITTQSKFLEIDLNTIQPEDLKQITTSFEFTSQYQ 245 Query: 542 TVLHGFAGYFNTVL----YKDVTLSICPESHSPGMFSWFPILFPIKQPIPMREGDTV 594 F +F+ V +K V S P + W +F ++ +P++ D + Sbjct: 246 EYCQAFVAWFDCVFSRGPHKPVEFSTGPFTEGT---HWKQTVFYLENDLPLKPNDVI 299 >3R0Q-C nrPDB Length = 376 Score = 187 bits (474), Expect = 1e-47, Method: Composition-based stats. Identities = 67/347 (19%), Positives = 115/347 (33%), Gaps = 65/347 (18%) Query: 290 PNAYEMFAKGYEDYLQSPLQPLMDNLESQTYE-VFEKDPVKYSQYQQAVYKCLLDRVPEE 348 P+A Y Y + ++ D V+ Y AV++ Sbjct: 15 PSAPVDKEVDYAQYFCTY--------SFLYHQKDMLSDRVRMDAYFNAVFQN-------- 58 Query: 349 EKETNIQILMVLGAGRGPLVNASLRAAKQAERKIKVYAVEKNPNAVITLEGWRYEEWGSQ 408 + + ++ +G G G L S A+ RK VYAVE A + Sbjct: 59 KHHFEGKTVLDVGTGSGILAIWS---AQAGARK--VYAVEATKMADHARALVKANNLDHI 113 Query: 409 VTVVSGDMREWKAPEKADIIVSELLGSFGDNE-LSPECLDGAQHFLKDDGVSIPGEYTSY 467 V V+ G + + PEK D+I+SE +G F E + + +LK GV P + Sbjct: 114 VEVIEGSVEDISLPEKVDVIISEWMGYFLLRESMFDSVISARDRWLKPTGVMYPSHARMW 173 Query: 468 LAPISSS------------------------KLYNEVRACREK---DRDPEAQFEMPYVV 500 LAPI S+ Y K + + + Sbjct: 174 LAPIKSNIADRKRNDFDGAMADWHNFSDEIKSYYGVDMGVLTKPFAEEQEKYYIQTAMWN 233 Query: 501 RLHNFHQLSDPLPC--FTFHHPNKDDVIDNNRYCCLQYRVDLNTVLHGFAGYFNTVL--- 555 L+ + P + ++ + ++ +T L GF G+F+ Sbjct: 234 DLNPQQIIGTPTIVKEMDCLTASVSEIEEVRSNVTSVINME-HTRLCGFGGWFDVQFSGR 292 Query: 556 -----YKDVTLSICP-ESHSPGMFSWFPILFPIKQPIPMREGDTVCV 596 +++ L+ P E H W +F + PI + EGD + + Sbjct: 293 KEDPAQQEIELTTAPSEQHCT---HWGQQVFIMSNPINVEEGDNLNL 336 >5LV5-A nrPDB Length = 403 Score = 187 bits (474), Expect = 1e-47, Method: Composition-based stats. Identities = 59/290 (20%), Positives = 98/290 (33%), Gaps = 28/290 (9%) Query: 316 ESQTYEVFEKDPVKYSQYQQAVYKCLLDRVPEEEKETNIQILMVLGAGRGPLVNASLRAA 375 + +E D V+ Y+ + K + ++ +GAG G L S+ A Sbjct: 81 DVSVHEEMIADQVRTEAYRLGILKNWAAL--------RGKTVLDVGAGTGIL---SIFCA 129 Query: 376 KQAERKIKVYAVEKNPNAVITLEGWRYEEWGSQVTVVSGDMREWKAPEKADIIVSELLGS 435 + R+ VYAVE + E R +V V+ G + + PE+ D IVSE +G Sbjct: 130 QAGARR--VYAVEASAIWQQAREVVRLNGLEDRVHVLPGPVETVELPERVDAIVSEWMGY 187 Query: 436 -FGDNELSPECLDGAQHFLKDDGVSIPGEYTSYLAPISSSKLYNEVRACREKDRDPEAQF 494 + L +LK+ G+ +P ++APIS L E R +Q Sbjct: 188 GLLHESMLSSVLHARTKWLKEGGLLLPASAELFVAPISDQML--EWRLGFW------SQV 239 Query: 495 EMPYVVRLHNFHQLSDPLPCFTFHHPNKDDVIDNNRYCCLQYRVD-LNTVLHGFAGYFNT 553 + Y V + + C H + R L G Sbjct: 240 KQHYGVDMSCMESFA--TRCLMGHSEIVVQDLSGEDVLARPQRFAQLELARAGLEQELEA 297 Query: 554 VLYKDVTLSICPESHSPGMFSWFPILFP---IKQPIPMREGDTVCVRFWR 600 + S + G WF + FP ++P+ + W+ Sbjct: 298 GVGGRFRCSCYGSAPLHGFAVWFQVTFPGGDSEKPLVLSTSPLHPATHWK 347 >5EGS-A nrPDB Length = 376 Score = 183 bits (465), Expect = 2e-46, Method: Composition-based stats. Identities = 57/290 (19%), Positives = 98/290 (33%), Gaps = 28/290 (9%) Query: 316 ESQTYEVFEKDPVKYSQYQQAVYKCLLDRVPEEEKETNIQILMVLGAGRGPLVNASLRAA 375 + +E D V+ Y+ + + + ++ +GAG G L S+ A Sbjct: 54 DVSVHEEMIADRVRTDAYRLGILRNWAAL--------RGKTVLDVGAGTGIL---SIFCA 102 Query: 376 KQAERKIKVYAVEKNPNAVITLEGWRYEEWGSQVTVVSGDMREWKAPEKADIIVSELLGS 435 + R+ VYAVE + E R+ +V V+ G + + PE+ D IVSE +G Sbjct: 103 QAGARR--VYAVEASAIWQQAREVVRFNGLEDRVHVLPGPVETVELPEQVDAIVSEWMGY 160 Query: 436 -FGDNELSPECLDGAQHFLKDDGVSIPGEYTSYLAPISSSKLYNEVRACREKDRDPEAQF 494 + L +LK+ G+ +P ++ PIS L E R +Q Sbjct: 161 GLLHESMLSSVLHARTKWLKEGGLLLPASAELFIVPISDQML--EWRLGFW------SQV 212 Query: 495 EMPYVVRLHNFHQLSDPLPCFTFHHPNKDDVIDNNRYCCLQYRVD-LNTVLHGFAGYFNT 553 + Y V + + C H + R L G Sbjct: 213 KQHYGVDMSCLEGFA--TRCLMGHSEIVVQGLSGEDVLARPQRFAQLELSRAGLEQELEA 270 Query: 554 VLYKDVTLSICPESHSPGMFSWFPILFP---IKQPIPMREGDTVCVRFWR 600 + S + G WF + FP ++P+ + W+ Sbjct: 271 GVGGRFRCSCYGSAPMHGFAIWFQVTFPGGESEKPLVLSTSPFHPATHWK 320 >5FUB-A nrPDB Length = 337 Score = 183 bits (464), Expect = 2e-46, Method: Composition-based stats. Identities = 53/295 (17%), Positives = 96/295 (32%), Gaps = 35/295 (11%) Query: 319 TYEVFEKDPVKYSQYQQAVYKCLLDRVPEEEKETNIQILMVLGAGRGPLVNASLRAAKQA 378 + D + Y+Q + ++++ LG G G + SL A Sbjct: 18 LHLEMLSDKPRTETYRQVILSNSAAL--------REKVVLDLGCGTGVI---SLFCALL- 65 Query: 379 ERKIKVYAVEKNPNAVITLEGWRYEEWGSQVTVVSGDMREWKAPEKADIIVSELLGSFGD 438 + VYAVE + A T E + VTV P K D++VSE +G+ Sbjct: 66 AKPAGVYAVEASSMAEHTEELVKQNGCDGVVTVFQERAENLTLPTKVDVLVSEWMGNCLL 125 Query: 439 NE-LSPECLDGAQHFLKDDGVSIPGEYTSYLAPISSSKLYNE----------VRACREKD 487 E + L +LK G+ P + P + Y + + + Sbjct: 126 FEYMLESVLLARDRWLKKGGMMWPSSACLTIVPCQAFSDYRQKVEFWENPYGLNFSYLQS 185 Query: 488 RDPEAQFEMPYVVRLHNFHQLSDPL--PCFTFHHPNKDDVIDNNRYCCLQYRVDLNTV-- 543 + P + + Q D L P + + ++ + Sbjct: 186 LAQKEFLSKP---KFSHHLQPEDCLSTPADVITLDMVTIQVSDLERLKGEFTFTVEKSGM 242 Query: 544 LHGFAGYFNTVLYKDVTLSICPESHSPGMF----SWFPILFPIKQPIPMREGDTV 594 HGF +F + ++ + + G + W LF + P+ + EGD + Sbjct: 243 FHGFTVWF-SAHFQCLEEDGPSIELNTGPYSEITHWKQTLFMLDAPVSVEEGDII 296 >3X0D-A nrPDB Length = 655 Score = 177 bits (449), Expect = 1e-44, Method: Composition-based stats. Identities = 56/287 (19%), Positives = 115/287 (40%), Gaps = 28/287 (9%) Query: 336 AVYKCLLDRVPEEEKETNIQILMVLGAGRGPLVNASLRAAKQAERKIKVYAVEKNPNAVI 395 A K + E + + + + +G G G L SL AA++ K+ V K P Sbjct: 56 AGLKTTIAEKKHENTDGKVHV-LDIGTGTGLL---SLMAAREGADKVTALEVFK-PMGDC 110 Query: 396 TLEGWRYEEWGSQVTVVSGDMREWK--APEKADIIVSELLGSFGDNELSPECLDGAQHFL 453 W ++TV+S + +ADIIV+E+ + E + A L Sbjct: 111 ARHITSNSPWSDKITVISERSTDVSQIGGSRADIIVAEVFDTELIGEGALRTFKEALERL 170 Query: 454 KDDGV-SIPGEYTSYLAPISSS--KLYNEV-RACREKDRDP-------EAQFEMPYV-VR 501 G +P Y+ P+ S K++N++ R EKD +P A F++ ++ Sbjct: 171 AKPGCRVVPSTGNVYIVPVESHLLKMFNDIPRLNGEKDEEPLGRCSGTAAVFDVQLSEMK 230 Query: 502 LHNFHQLSDPLPCFTFHHPNKDDVIDNNRYCCLQYRVDLNTVLHGFAGYFNTVLYKDVT- 560 H F +LS+P+ F F +++ +I + + + + + +++ + ++ T Sbjct: 231 THEFRELSEPIVAFKFDFEHEEKIIFDESFVR-EAVAHSSGTIDALLMWWDIDMDRNGTT 289 Query: 561 -LSICPESHSPGMF----SWFPILF--PIKQPIPMREGDTVCVRFWR 600 + + P+ + + W ++ P K+ + M + + Sbjct: 290 FIDMGPKWKNKNNYAWRDHWMQAVYYLPEKKKVEMNQTFEIVCNHDE 336 >4M36-A nrPDB Length = 343 Score = 165 bits (418), Expect = 5e-41, Method: Composition-based stats. Identities = 68/301 (22%), Positives = 109/301 (36%), Gaps = 48/301 (15%) Query: 320 YEVFEKDPVKYSQYQQAVYKCLLDRVPEEEKETNIQILMVLGAGRGPLVNASLRAAKQAE 379 + D + + Y + + K + ++ +GAG G L SL AAK Sbjct: 37 HYAMMNDEERNNFYYEVLKKHVTPETG----------VLEIGAGSGLL---SLMAAKLGA 83 Query: 380 RKIKVYAVEKNP-NAVITLEGWRYEEWGSQVTVV---SGDMREWKAPEKADIIVSELLGS 435 + V AVE + A + E R QV V+ S +++ PE D+++SE+ G+ Sbjct: 84 KW--VVAVEGSEELAKLARENIRANNMEHQVKVLHMMSTELKSKHLPEPPDVLLSEIFGT 141 Query: 436 FGDNE-LSPECLDGAQHFLKDDGVSIPGEYTSYLAPISSSKLYNEVRACREKDRDPEAQ- 493 E +D LK IP T Y PI L+ +D D + Sbjct: 142 MMLGESALDYVVDVRNRLLKPTTKIIPQFGTQYAVPIECDALHRISSVSGWRDLDLKHMM 201 Query: 494 ---------FEMPYVVRLH--NFHQLSDPLPCF--TFHHPNKDDVIDNNRYCCLQYRVDL 540 F Y +R++ NF +LSDP+ F F N++D+ + V Sbjct: 202 TLQDTVSIVFAKHYGIRMNSVNFRRLSDPIELFRVDFSSSNRNDIPRRKHFD----VVAK 257 Query: 541 NTVLHGFAGYFNTVLYKDVTLSICPESHS---PGMFSWFPILF-------PIKQPIPMRE 590 + ++ V + +S PE P W L P+ P+ E Sbjct: 258 ESGTAHAMLFYWKVTDDEFVMSTDPEDTVNNFPRDMQWGQALQLLDASNGPLPTPVVFTE 317 Query: 591 G 591 G Sbjct: 318 G 318 >5EKU-A nrPDB Length = 390 Score = 164 bits (415), Expect = 1e-40, Method: Composition-based stats. Identities = 68/301 (22%), Positives = 109/301 (36%), Gaps = 48/301 (15%) Query: 320 YEVFEKDPVKYSQYQQAVYKCLLDRVPEEEKETNIQILMVLGAGRGPLVNASLRAAKQAE 379 + D + + Y + + K + ++ +GAG G L SL AAK Sbjct: 72 HYAMMNDEERNNFYYEVLKKHVTPETG----------VLEIGAGSGLL---SLMAAKLGA 118 Query: 380 RKIKVYAVEKNP-NAVITLEGWRYEEWGSQVTVV---SGDMREWKAPEKADIIVSELLGS 435 + V AVE + A + E R QV V+ S +++ PE D+++SE+ G+ Sbjct: 119 KW--VVAVEGSEELAKLARENIRANNMEHQVKVLHMMSTELKPKHLPEPPDVLLSEIFGT 176 Query: 436 FGDNE-LSPECLDGAQHFLKDDGVSIPGEYTSYLAPISSSKLYNEVRACREKDRDPEAQ- 493 E +D LK IP T Y PI L+ +D D + Sbjct: 177 MMLGESALDYVVDVRNRLLKPTTKIIPQFGTQYAVPIECDALHRISSVSGWRDLDLKHMM 236 Query: 494 ---------FEMPYVVRLH--NFHQLSDPLPCF--TFHHPNKDDVIDNNRYCCLQYRVDL 540 F Y +R++ NF +LSDP+ F F N++D+ + V Sbjct: 237 TLQDTVSIVFAKHYGIRMNSVNFRRLSDPIELFRVDFSSSNRNDISRRKHFD----VVAK 292 Query: 541 NTVLHGFAGYFNTVLYKDVTLSICPESHS---PGMFSWFPILF-------PIKQPIPMRE 590 + ++ V + +S PE P W L P+ P+ E Sbjct: 293 ESGTAHAMLFYWKVTDDEFVMSTDPEDTVNNFPRDMQWGQALQLLDASNGPLPTPVVFTE 352 Query: 591 G 591 G Sbjct: 353 G 353 >4LWO-B nrPDB Length = 368 Score = 121 bits (304), Expect = 8e-28, Method: Composition-based stats. Identities = 68/393 (17%), Positives = 134/393 (34%), Gaps = 89/393 (22%) Query: 293 YEMFAKGYEDYLQSPLQPLMDNLESQTYEVFEKDPVKYSQYQQAVYKCLLDRVPEEEKET 352 Y+ + + Y +S + + + +D + S Y++++ E+ Sbjct: 10 YDPNSSLHHQYYESYS-------DLAVHRLMLEDAQRMSFYRKSI---------EQSASI 53 Query: 353 NIQILMVLGAGRGPLVNASLRAAKQAERKIKVYAVEKNPNAVITLEGWRYEEWGSQVTVV 412 ++++ +G+G G L S+ AA+ + V+++E + + + + +++TV+ Sbjct: 54 EGKVVVDVGSGTGIL---SMWAARAGAKH--VFSIEASSLSEFQIGVVEDNDLSTKITVL 108 Query: 413 SGDMREWKAPEKAD---------------IIVSELLGSFGDNE-LSPECLDGAQHF---- 452 + A A+ +++SE +G + +E + P + F Sbjct: 109 GDTVENIIAGGVANFVNRHKAKLGKCGVAVLLSEWMGFYLFHEGMLPSVIRARNFFQDVN 168 Query: 453 ----LKDDGVSIPGEYTSYLAPISSSKLYNEVRACREKD---RDPEAQFEMPYVVRLHNF 505 + IP T ++API+ Y + +D D + Y V L Sbjct: 169 AALGVLQPIEMIPERATVFVAPITCKPYYVQRYKNFWRDVDGLDFSRYGRIEYEVYLEQA 228 Query: 506 HQLSDPLPCFTFHHPNKDDVIDNNRYCCLQYRVDLNTVLH-------------------- 545 L + LP H + N + L+ +H Sbjct: 229 SPLVECLPPLCLLHEGLSLIELNLSTVQEEVLTSLHNTVHFDLKESAEFQQHAREAGSEG 288 Query: 546 -----GFAGYFNTVLYKDVTLSICPESHSPGMFSWFPILFPIKQPIPMREGDTVCVRFWR 600 GF +F+ V Y TLS P S S W + P R + V Sbjct: 289 RVSVDGFTVWFD-VSYGAHTLSTSPRSPST---HWKQTTILL--PREARNEELVSFP--- 339 Query: 601 CNNGKKVWYEWAVTSPVCSAIHNPTGRSYTIGL 633 G ++ E +++ + T R YTI L Sbjct: 340 -VEGGELGVEMHISAS------DKTLRFYTIEL 365 >6OGN-A nrPDB Length = 692 Score = 92.6 bits (228), Expect = 4e-19, Method: Composition-based stats. Identities = 59/333 (17%), Positives = 116/333 (34%), Gaps = 50/333 (15%) Query: 320 YEVFEKDPVKYSQYQQAVYKCLLDRVPEEEKETNIQILMVLGAGRGPLVNASLRAAKQAE 379 Y D + +Y Y+ + V + +++ +G G G L S+ A Sbjct: 35 YADMLHDKDRNIKY----YQGIRAAVSRVKDRGQKALVLDIGTGTGLL---SMMAVTAGA 87 Query: 380 RKIKVYAVEKNPNAVITLEGWRYEEWGSQVTVVSGDMREWK------APEKADIIVSELL 433 V K P A ++ + ++ V++ E P +A+I+++EL Sbjct: 88 DFCYAIEVFK-PMAEAAVKIVERNGFSDKIKVINKHSTEVTVGPDGDLPCRANILITELF 146 Query: 434 GSFGDNELSPECLDGAQHFLKDDGV-SIPGEYTSYLAPISSSKLYNEVRA--------CR 484 + E + + A L + ++P T Y + S ++++ + Sbjct: 147 DTELIGEGALPSYEHAHKHLVQEDCEAVPHRATVYAQLVESRRMWSWNKLFPVRVRTSLG 206 Query: 485 EKDRDPEAQFEM----PYVVRLH-------NFHQLSDPLPCFTFHHPNKDDVIDNNRYCC 533 E+ P ++ E P V + +F LSD LP F+ + ++ C Sbjct: 207 EQVIVPPSELERCPGAPSVCDIQLNQVSPADFTVLSDVLPMFSVDF---SKQVSSSAACH 263 Query: 534 LQYRVDL-----NTVLHGFAGYFNTVLYKDVTLS-----ICPESHSPGMFSWFPILFPIK 583 + V L VL + + T++ P+ W ++ + Sbjct: 264 SRQFVPLASGQAQVVLSWWDIEMDPEGKIKCTMAPFWAQTDPQELQ-WRDHWMQCVYFLP 322 Query: 584 QPIPMREGDTVCVRFWRCNNGKKVWYEWAVTSP 616 Q P+ +G C+ ++ VWY TSP Sbjct: 323 QEEPVVQGSPRCLV--AHHDDYCVWYSLQRTSP 353 >1L3B-A nrPDB Length = 192 Score = 47.5 bits (111), Expect = 2e-05, Method: Composition-based stats. Identities = 30/110 (27%), Positives = 49/110 (44%), Gaps = 11/110 (10%) Query: 352 TNIQILMVLGAGRGPLVNASLRAAKQAERKIKVYAVEKNPNAVITLE-GWRYEEWGSQVT 410 + + +G G G + + A R +VYA+++NP A+ T E + G VT Sbjct: 32 GKNDVAVDVGCGTGGVTL------ELAGRVRRVYAIDRNPEAISTTEMNLQRHGLGDNVT 85 Query: 411 VVSGDMREWKAPEKADIIVSELLGSFGDNELSPECLDGAQHFLKDDGVSI 460 ++ GD E + DI ++ + GS G+ E L + LK G I Sbjct: 86 LMEGDAPE-ALCKIPDIDIAVVGGSGGE---LQEILRIIKDKLKPGGRII 131 >4FS8-A nrPDB Length = 383 Score = 42.1 bits (97), Expect = 8e-04, Method: Composition-based stats. Identities = 48/293 (16%), Positives = 88/293 (30%), Gaps = 54/293 (18%) Query: 335 QAVYKCLLDRVPEEEKETNIQILMVLGAGRGPLVNASLRAAKQAERKIKVYAVEKNPN-A 393 + Y C + E ++ LG G G A+K KV V+ N Sbjct: 67 EKFYGCGSTLPADGSLEGA--TVLDLGCGTG---RDVYLASKLVGEHGKVIGVDMLDNQL 121 Query: 394 VITLEGWRY-------EEWGSQVTVVSGDMREWKAPEK-------ADIIVSELLGSFGDN 439 + + Y S V + G + E DI++S + + N Sbjct: 122 EVARKYVEYHAEKFFGSPSRSNVRFLKGFIENLATAEPEGVPDSSVDIVISNCVCNLSTN 181 Query: 440 ELSPECLDGAQHFLKDDGVSIPGEYTSYLAPISSSKLYNEVRACREKDRDPEAQFE-MPY 498 +L+ L+D G S +Y + R +DP E + Sbjct: 182 KLAL--FKEIHRVLRDGGELY------------FSDVYADRRLSEAAQQDPILYGECLGG 227 Query: 499 VVRLHNFHQLSD----------PLPCFTFHHPNKDDVIDNNRYCCLQYR-VDLNTVLHGF 547 + L +F +L + P ++ + ++ +R + T+ Sbjct: 228 ALYLEDFRRLVAEAGFRDVRLVSVGPVDVSDPQLRKLVPDVQFYSCTFRCFKVATLEATR 287 Query: 548 AGYFNTVLYKDVTLSICPESHSPGMFSWFPILFPIKQPIPMREGDTVCVRFWR 600 Y + Y I E F+ FP ++P+ + +R R Sbjct: 288 EDYGQSATY---LGGIGEEFKLDRFFT-----FPREKPVRVDRNTAEIIRHSR 332 >4PNE-A nrPDB Length = 302 Score = 42.1 bits (97), Expect = 8e-04, Method: Composition-based stats. Identities = 18/104 (17%), Positives = 33/104 (31%), Gaps = 7/104 (6%) Query: 357 LMVLGAGRGPLVNASLRAAKQAERKIKVYAVEKNPNAVITLEGWRYEEWGSQVTVVSGDM 416 L+ +G G G +LR A+ +I V + A I + R +V + Sbjct: 96 LLDVGCGTG---QPALRVARDNAIQITGITVSQVQVA-IAADCARERGLSHRVDF--SCV 149 Query: 417 REWKAPEKADIIVSEL-LGSFGDNELSPECLDGAQHFLKDDGVS 459 P + + + S + + LK G+ Sbjct: 150 DAMSLPYPDNAFDAAWAMQSLLEMSEPDRAIREILRVLKPGGIL 193 >3D2L-A nrPDB Length = 243 Score = 42.1 bits (97), Expect = 8e-04, Method: Composition-based stats. Identities = 25/116 (21%), Positives = 39/116 (33%), Gaps = 12/116 (10%) Query: 355 QILMVLGAGRGPLVNASLRAAKQAERKIKVYAVEKNP-NAVITLEGWRYEEWGSQVTVVS 413 + + +G G G A +V V+ + I E + E V Sbjct: 35 KRIADIGCGTGT-------ATLLLADHYEVTGVDLSEEMLEIAQE--KAMETNRHVDFWV 85 Query: 414 GDMREWKAPEKADI--IVSELLGSFGDNELSPECLDGAQHFLKDDGVSIPGEYTSY 467 DMRE + PE D I+ + L + D A L D G + ++ Y Sbjct: 86 QDMRELELPEPVDAITILCDSLNYLQTEADVKQTFDSAARLLTDGGKLLFDVHSPY 141 >6GKZ-A nrPDB Length = 351 Score = 41.7 bits (96), Expect = 0.001, Method: Composition-based stats. Identities = 42/255 (16%), Positives = 89/255 (34%), Gaps = 25/255 (9%) Query: 250 IFKLFKLEVQFVISGSHHHSEKDLCSYLQYLEYLSQNSP-PPNAYEMFAKGYEDYLQSPL 308 I +L + E+ + + + ++ + +Q L + + + ++ YE ++ L Sbjct: 24 IKQLIRRELARRLQWGYKPTYEEQIAEIQNLTHSLRQMKIATEVETLDSQLYEIPIE-FL 82 Query: 309 QPLMDNLESQTYEVFEKDPVKYSQYQQAVYKCLLDRVPEEEKETNIQILMVLGAGRGPLV 368 + + + + F++D + + A+ D E + + Q ++ LG G+G L Sbjct: 83 KIMNGSNLKGSCCYFKEDSTTLDEAEIAML----DLYCERAQIQDGQSVLDLGCGQGALT 138 Query: 369 NASLRAAKQAERKIKVYAVEKNPNAVITLEGWRYEEWGSQVTVVSGDMREWKAPEKAD-- 426 +K K V N+V E E + V + + E A+ Sbjct: 139 L-------HVAQKYKNCRVTAVTNSVSQKEYIEEESRRRNLLNVEVKLADITTHEMAETY 191 Query: 427 --IIVSELLGSFGDNELSPECLDGAQHFLKDDGVSIPGE-----YTSYLAPISSSKLYNE 479 I+V EL + EL + ++ DG+ + + P+ + E Sbjct: 192 DRILVIELFEHMKNYELLLRKI---SEWISKDGLLFLEHICHKTFAYHYEPLDDDDWFTE 248 Query: 480 VRACREKDRDPEAQF 494 P A F Sbjct: 249 YVFPAGTMIIPSASF 263 >5Z9O-A nrPDB Length = 399 Score = 40.9 bits (94), Expect = 0.002, Method: Composition-based stats. Identities = 37/200 (18%), Positives = 70/200 (35%), Gaps = 19/200 (9%) Query: 263 SGSHHHSEKDLCSYLQYLEYLSQNSPPP--NAYEMFAKGYEDYLQSPLQPLMDNLESQTY 320 + S S K +L ++ + S + Y++ Y+ +L + Sbjct: 85 ADSFMRSSK-FRKFLPKSKHTEKQSEEDVQSHYDIGNDFYKLWLDPTMTYSCAYFTDDNK 143 Query: 321 EVFEKDPVKYSQYQQAVYKCLLDRVPEEEKETNIQILMVLGAGRGPLVNASLRAAKQAER 380 + E+ + V+ L PE + L+ +G G G L+ L AAK+ Sbjct: 144 DDLEQAQIA------KVHHILNKLHPE-----KGKTLLDIGCGWGTLM---LTAAKEYGL 189 Query: 381 KIKVYAVEKNPNAVITLEGWRYEEWGSQVTVVSGDMREWKAPEKADIIVSELLGSFGDNE 440 K+ + + + E V D RE ++ D + S + +E Sbjct: 190 KVTGVTL-SEEQYKLVQKKIYDEGLEDVAEVKLEDYREL-GDQQWDYVTSVGMFEHVGSE 247 Query: 441 LSPECLDGAQHFLKDDGVSI 460 E +LK+DGV++ Sbjct: 248 NLGEYFKDVAKYLKNDGVAL 267 >1WY7-A nrPDB Length = 207 Score = 39.4 bits (90), Expect = 0.005, Method: Composition-based stats. Identities = 23/114 (20%), Positives = 42/114 (36%), Gaps = 17/114 (14%) Query: 351 ETNIQILMVLGAGRGPLVNASLRAAKQAERKIKVYAVEKNPNAVITLEGWRYEEWGSQVT 410 + +++ LGAG G L +L +++ V+K V+ E+ + Sbjct: 47 DIEGKVVADLGAGTGVLSYGALL---LGAKEVICVEVDKEAVDVL---IENLGEFKGKFK 100 Query: 411 VVSGDMREWKAPEKADI-IVSELLGS--------FGDNELSPECLDGAQHFLKD 455 V GD+ E+ + DI I++ GS F + + H K Sbjct: 101 VFIGDVSEFN--SRVDIVIMNPPFGSQRKHADRPFLLKAFEISDVVYSIHLAKP 152 >2IP2-A nrPDB Length = 334 Score = 38.2 bits (87), Expect = 0.012, Method: Composition-based stats. Identities = 31/150 (20%), Positives = 61/150 (40%), Gaps = 10/150 (6%) Query: 351 ETNIQILMVLGAGRGPLVNASLRAAKQAERKIKVYAVEKNPNAVITLEGWRYEEWGSQVT 410 + + + +G G G L A L+A + +++ + + + G +V+ Sbjct: 165 DFRGRSFVDVGGGSGELTKAILQAE----PSARGVMLDREGSLGVARDNLSSLLAGERVS 220 Query: 411 VVSGDMREWKAPEKADI-IVSELLGSFGDNELSPECLDGAQHFLKDDGVSIPGEYTSYL- 468 +V GDM + + P DI ++S ++G D S L + + DG + E T Sbjct: 221 LVGGDMLQ-EVPSNGDIYLLSRIIGD-LDEAASLRLLGNCREAMAGDGRVVVIERTISAS 278 Query: 469 --APISSSKLYNEVRACREKDRDPEAQFEM 496 +P+S + AC + R E ++ Sbjct: 279 EPSPMSVLWDVHLFMACAGRHRTTEEVVDL 308 >2ZZN-A nrPDB Length = 336 Score = 36.7 bits (83), Expect = 0.028, Method: Composition-based stats. Identities = 15/65 (23%), Positives = 31/65 (47%), Gaps = 8/65 (12%) Query: 356 ILMVLGAGRGPLVNASLRAAKQAERKIKVYAVEKNPNA-VITLEGWRYEEWGSQVTVVSG 414 +++ + AG GP A A K +YA++ NP+A + + + + ++ + Sbjct: 198 VVVDMFAGVGPFSIACKNAKK-------IYAIDINPHAIELLKKNIKLNKLEHKIIPILS 250 Query: 415 DMREW 419 D+RE Sbjct: 251 DVREV 255 >5FAD-A nrPDB Length = 161 Score = 35.5 bits (80), Expect = 0.065, Method: Composition-based stats. Identities = 26/124 (20%), Positives = 43/124 (34%), Gaps = 11/124 (8%) Query: 344 RVPEEEKETNIQILMVLGAGRGPLVNASLRAAKQAERKIKVYAVEKNPN-AVITLEGWRY 402 R+ E K + I+ LG G G ++ AAK K K VE N L Sbjct: 19 RMLEIAKVSQDDIVYDLGCGDGRIIIT---AAKDFNVK-KAVGVEINDERIREALANIEK 74 Query: 403 EEWGSQVTVVSGDMREWKAPEKADIIVSELLGSFGDNELSPECLDGAQHFLKDDGVSIPG 462 + ++V G+ E DI + ++ F ++ + LK + Sbjct: 75 NGVTGRASIVKGNFFEV------DISEATVVTMFLLTNVNEMLKPKLEKELKPGTRVVSH 128 Query: 463 EYTS 466 E+ Sbjct: 129 EFEI 132 >5I2H-A nrPDB Length = 364 Score = 34.4 bits (77), Expect = 0.16, Method: Composition-based stats. Identities = 15/90 (16%), Positives = 35/90 (38%), Gaps = 4/90 (4%) Query: 344 RVPEEEKETNIQILMVLGAGRGPLVNASLRAAKQAERKIKVYAVEKNPNAVITLEGWRYE 403 ++ ++ ++ ++L+ + G G A Q + ++ I E Sbjct: 187 KILKDNSGSSGRVLLDVAGGSGIYT----MAVLQKYPTWRGIIFDRPEVLKIAAELAEQT 242 Query: 404 EWGSQVTVVSGDMREWKAPEKADIIVSELL 433 ++ + +GDM P DI++S +L Sbjct: 243 GVRDRLELHAGDMWVDPFPPADDILLSNVL 272 >1DUS-A nrPDB Length = 194 Score = 33.6 bits (75), Expect = 0.25, Method: Composition-based stats. Identities = 21/109 (19%), Positives = 37/109 (33%), Gaps = 7/109 (6%) Query: 353 NIQILMVLGAGRGPLVNASLRAAKQAERKIKVYAVEKNPNAVITLEGWRYEEWGS-QVTV 411 ++ LG G G + A E K A + E + + + V Sbjct: 52 KDDDILDLGCGYGVIGI-----ALADEVKSTTMADINRRAIKLAKENIKLNNLDNYDIRV 106 Query: 412 VSGDMREWKAPEKADIIVSELLGSFGDNELSPECLDGAQHFLKDDGVSI 460 V D+ E K + I++ G E+ ++ + LKD+G Sbjct: 107 VHSDLYENVKDRKYNKIITNPPIRAG-KEVLHRIIEEGKELLKDNGEIW 154 >4WXH-A nrPDB Length = 367 Score = 33.6 bits (75), Expect = 0.27, Method: Composition-based stats. Identities = 17/78 (21%), Positives = 28/78 (35%), Gaps = 5/78 (6%) Query: 352 TNIQILMVLGAGRGPLVNASLRAAKQAERKIKVYAVEKNPNAVITLEGWRYEEWGSQVTV 411 TN++ ++ +G A + + +E + E +V V Sbjct: 188 TNVRHVLDVGG----GKGGFAAAIARRAPHVSATVLEMAGTVDTARSYLKDEGLSDRVDV 243 Query: 412 VSGDMREWKAPEKADIIV 429 V GD E P KAD I+ Sbjct: 244 VEGDFFE-PLPRKADAII 260 >2XVM-A nrPDB Length = 199 Score = 33.6 bits (75), Expect = 0.27, Method: Composition-based stats. Identities = 26/128 (20%), Positives = 43/128 (33%), Gaps = 9/128 (7%) Query: 330 YSQYQQAVYKCLLDRVPEEEKETNIQILMVLGAGRGPLVNASLRAAKQAERKIKVYAVEK 389 +Y+ V E K + LG G G SL A V A +K Sbjct: 12 TDKYE---LTRTHSEVLEAVKVVKPGKTLDLGCGNG---RNSLYLAANGYD---VDAWDK 62 Query: 390 NPNAVITLEGWRYEEWGSQVTVVSGDMREWKAPEKADIIVSELLGSFGDNELSPECLDGA 449 N ++ +E + E + D+ + D I+S ++ F + + P + Sbjct: 63 NAMSIANVERIKSIENLDNLHTRVVDLNNLTFDRQYDFILSTVVLMFLEAKTIPGLIANM 122 Query: 450 QHFLKDDG 457 Q K G Sbjct: 123 QRCTKPGG 130 >3CJR-A nrPDB Length = 254 Score = 32.9 bits (73), Expect = 0.46, Method: Composition-based stats. Identities = 18/102 (17%), Positives = 33/102 (32%), Gaps = 14/102 (13%) Query: 357 LMVLGAGRGPLVNASLRAAKQAERKIKVYAVEKNPNAV-ITLEGWRYEEWGSQVTVVSGD 415 ++ LG G G L A A K + V+ +P + + + + G Sbjct: 124 VLDLGTGSGVLAIA---AEKLGGK---ALGVDIDPMVLPQAEANAKRNGVRPR--FLEGS 175 Query: 416 MREWKAPEKADIIVSELLGSFGDNELSPECLDGAQHFLKDDG 457 + D++V+ L L+P + L G Sbjct: 176 LEAALPFGPFDLLVANLYA-ELHAALAPRY----REALVPGG 212 >5WP4-A nrPDB Length = 491 Score = 32.5 bits (72), Expect = 0.59, Method: Composition-based stats. Identities = 24/118 (20%), Positives = 38/118 (32%), Gaps = 10/118 (8%) Query: 355 QILMVLGAGRGPLVNASLRAAKQAERKIKVYAVEKNPNAVITLEGWRYEEWGSQVTVVSG 414 Q ++ +G G G A K + V ++ + N I+ R V Sbjct: 284 QKVLDVGCGIG--GGDFYMAEKFD---VHVVGIDLSVNM-ISFALERAIGLSCSVEFEVA 337 Query: 415 DMREWKAPEKA-DIIVSELLGSFGDNELSPECLDGAQHFLKDDG-VSIPGEYTSYLAP 470 D P+ + D+I S + + P +LK G V I S P Sbjct: 338 DCTTKHYPDNSFDVIYSR--DTILHIQDKPALFRTFFKWLKPGGKVLISDYCRSPKTP 393 >2I6G-A nrPDB Length = 199 Score = 32.5 bits (72), Expect = 0.67, Method: Composition-based stats. Identities = 24/100 (24%), Positives = 38/100 (38%), Gaps = 6/100 (6%) Query: 358 MVLGAGRGPLVNASLRAAKQAERKIKVYAVEKNPNAVITLEGWRYEEWGSQVTVVSGDMR 417 + LG G G SL A V A +KNP ++ LE + E + D+ Sbjct: 36 LDLGCGNG---RNSLYLAANGYD---VTAWDKNPASMANLERIKAAEGLDNLQTDLVDLN 89 Query: 418 EWKAPEKADIIVSELLGSFGDNELSPECLDGAQHFLKDDG 457 + D I+S ++ F + + P + Q K G Sbjct: 90 TLTFDGEYDFILSTVVMMFLEAQTIPGLIANMQRCTKPGG 129 >3GRV-A nrPDB Length = 295 Score = 32.1 bits (71), Expect = 0.69, Method: Composition-based stats. Identities = 19/77 (24%), Positives = 34/77 (44%), Gaps = 8/77 (10%) Query: 339 KCLLDRVPEEEKETNIQILMVLGAGRGPLVNASLRAAKQAERKIKVYAVEKN--PNAVIT 396 K +++ E T +++ +G G+G L + AK K+ V ++K+ P A Sbjct: 36 KNFVNKAVESANLTKDDVVLEIGLGKGILTEELAKNAK----KVYVIEIDKSLEPYANKL 91 Query: 397 LEGWRYEE--WGSQVTV 411 E + E WG + V Sbjct: 92 KELYNNIEIIWGDALKV 108 >3FYD-A nrPDB Length = 263 Score = 32.1 bits (71), Expect = 0.69, Method: Composition-based stats. Identities = 19/77 (24%), Positives = 34/77 (44%), Gaps = 8/77 (10%) Query: 339 KCLLDRVPEEEKETNIQILMVLGAGRGPLVNASLRAAKQAERKIKVYAVEKN--PNAVIT 396 K +++ E T +++ +G G+G L + AK K+ V ++K+ P A Sbjct: 7 KNFVNKAVESANLTKDDVVLEIGLGKGILTEELAKNAK----KVYVIEIDKSLEPYANKL 62 Query: 397 LEGWRYEE--WGSQVTV 411 E + E WG + V Sbjct: 63 KELYNNIEIIWGDALKV 79 >5LNK-k nrPDB Length = 320 Score = 32.1 bits (71), Expect = 0.73, Method: Composition-based stats. Identities = 18/100 (18%), Positives = 39/100 (39%), Gaps = 14/100 (14%) Query: 236 KKGFPVLTKVHQRLIFKLFKLEVQFVISGSHHHSEKDLCSYLQYLEYLSQNSPPPNAYEM 295 KKG P H+ I + +++ V G+ + C LQY + ++++ Sbjct: 185 KKGNP-----HEMKITSAYLQDIENVYKGTFLPEMSEKCEVLQYSAWEAEDAEK------ 233 Query: 296 FAKGYEDYLQSPLQPLMDNLESQTYE--VFEKDPVKYSQY 333 YL+ P +D + + + + +D ++ Y Sbjct: 234 -VVEDIQYLKYDKGPWLDQDDRKLHNLRMLVQDKLEVLNY 272 >2Z4T-A nrPDB Length = 514 Score = 32.1 bits (71), Expect = 0.77, Method: Composition-based stats. Identities = 17/112 (15%), Positives = 34/112 (30%), Gaps = 3/112 (2%) Query: 139 VGHHSTMFWMRVPLMAPNDLRDDLIENEPISLSEEDNSGEERTWIWWHNFRSLCDYNKKI 198 G S W ++ + LR D + EP D G+ + W F+ +K+ Sbjct: 274 TGTSSVYNWQKLYPANYHFLRKDYLTLEPSLHELRDYIGDSLKQMQWDGFKKF--NSKQQ 331 Query: 199 ALAIEIGADLPSGHVIDRWLGEPIKAAFLPTSIFLTNKKGFPVLTKVHQRLI 250 L + I + + + + + + K +I Sbjct: 332 ELFLSI-VNFDKQKLQNEYNSSNLPNFVFTGTTVWAGNHEREYYAKQQINVI 382 >6HV9-A nrPDB Length = 914 Score = 31.3 bits (69), Expect = 1.2, Method: Composition-based stats. Identities = 9/48 (18%), Positives = 24/48 (50%) Query: 257 EVQFVISGSHHHSEKDLCSYLQYLEYLSQNSPPPNAYEMFAKGYEDYL 304 + ++ ++ +S ++ +Y QY+ + +P + ++ K Y D L Sbjct: 555 DRNQILIKTNKYSPENCYAYSQYMMKAVRTNPMFSYLDLNIKRYWDLL 602 >6C5B-A nrPDB Length = 341 Score = 30.9 bits (68), Expect = 1.7, Method: Composition-based stats. Identities = 24/106 (22%), Positives = 44/106 (41%), Gaps = 5/106 (4%) Query: 355 QILMVLGAGRGPLVNASLRAAKQAERKIKVYAVEKNPNAVITLEGWRYEEWGSQVTVVSG 414 + ++ +GAG GPL++A LR+ +A ++ A + G + V G Sbjct: 176 KTVIDIGAGYGPLLSAILRSQPEARG----ILFDQPHVAQAAGKRLAEAGVGDRCGTVGG 231 Query: 415 DMREWKAPEKADIIVSELLGSFGDNELSPECLDGAQHFLKDDGVSI 460 D + P D+ + LL D++ S E L + + G + Sbjct: 232 DFF-VEVPADGDVYILSLLLHDWDDQRSIEILRNCRRAMPAHGKLL 276 >2ICS-A nrPDB Length = 379 Score = 30.5 bits (67), Expect = 2.1, Method: Composition-based stats. Identities = 18/48 (37%), Positives = 27/48 (56%) Query: 194 YNKKIALAIEIGADLPSGHVIDRWLGEPIKAAFLPTSIFLTNKKGFPV 241 YNK + I G D + HV + L E +KAA + T I++ N++ PV Sbjct: 236 YNKGVVFDIGHGTDSFNFHVAETALREGMKAASISTDIYIRNRENGPV 283 >2PJD-A nrPDB Length = 343 Score = 30.2 bits (66), Expect = 2.8, Method: Composition-based stats. Identities = 19/99 (19%), Positives = 35/99 (35%), Gaps = 10/99 (10%) Query: 357 LMVLGAGRGPLVNASLRAAKQAERKIKVYAVEKNPNAVITLEGWRYEEWGSQVTVVSGDM 416 ++ +G G G L A A + ++ + V P + +V S Sbjct: 200 VLDVGCGAGVLSVA--FARHSPKIRLTLCDVSA-PAVEASRATLAANGVEGEV-FASNVF 255 Query: 417 REWKAPEKADIIVSELLGSFGDNELSPECLDGAQHFLKD 455 E K + D+I+S ++ LD AQ ++ Sbjct: 256 SEVKG--RFDMIISNP----PFHDGMQTSLDAAQTLIRG 288 >5ME5-A nrPDB Length = 237 Score = 29.8 bits (65), Expect = 3.7, Method: Composition-based stats. Identities = 18/63 (28%), Positives = 23/63 (36%), Gaps = 5/63 (7%) Query: 125 DNSNLSRLLINHIHVGHHSTMFWMRVPLMAPNDLRDDLIENEPISLSEEDNSGEERTWIW 184 D+SNLS L++ H HS FW P PI S E W Sbjct: 49 DSSNLSASLVHQPHPLEHSWTFWFDNPSAKSKQATWGA-SIRPI----YTFSTVEEFWSV 103 Query: 185 WHN 187 ++N Sbjct: 104 YNN 106 >4KRG-A nrPDB Length = 466 Score = 28.6 bits (62), Expect = 9.4, Method: Composition-based stats. Identities = 22/127 (17%), Positives = 40/127 (31%), Gaps = 16/127 (12%) Query: 355 QILMVLGAGRGPLVNASLRAAKQAERKIKVYAVEKNPNAVITLEGWRYEEWGSQVTVVSG 414 + ++ +GAG G + R + ++ Q+ G Sbjct: 59 KDVVDIGAGIGRFTTVL----AETARWVLSTDFIESFIEKNQERNAHMGNISYQI----G 110 Query: 415 DMREWKAPEK-ADIIVSELLGSFGDNELSPECLDGAQHFLKDDG-------VSIPGEYTS 466 D + EK D++ + L + + E L A +L+ DG S P Sbjct: 111 DAVHLQMDEKSVDLVFTNWLMMYLSDREVIEFLLNAMRWLRADGYIHLRESCSEPSTGRL 170 Query: 467 YLAPISS 473 A + S Sbjct: 171 KTATMHS 177 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.307 0.123 0.334 Lambda K H 0.267 0.0381 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 23,809,039 Number of Sequences: 36641 Number of extensions: 944330 Number of successful extensions: 2588 Number of sequences better than 10.0: 51 Number of HSP's better than 10.0 without gapping: 38 Number of HSP's successfully gapped in prelim test: 46 Number of HSP's that attempted gapping in prelim test: 2415 Number of HSP's gapped (non-prelim): 98 length of query: 633 length of database: 10,336,785 effective HSP length: 103 effective length of query: 530 effective length of database: 6,562,762 effective search space: 3478263860 effective search space used: 3478263860 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 62 (28.6 bits)