BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q64444 (305 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 3ZNC-A nrPDB 546 e-156 5JN8-A nrPDB 314 3e-86 5LL9-A nrPDB 144 5e-35 4LU3-A nrPDB 142 1e-34 1RJ5-A nrPDB 134 4e-32 5DVX-A nrPDB 134 7e-32 6G4T-A nrPDB 127 8e-30 3FE4-A nrPDB 126 9e-30 4QK3-A nrPDB 125 3e-29 1Z93-A nrPDB 120 6e-28 3D0N-A nrPDB 119 1e-27 4CNR-A nrPDB 116 1e-26 6FAF-A nrPDB 111 4e-25 1FLJ-A nrPDB 108 2e-24 2W2J-A nrPDB 107 4e-24 1URT-A nrPDB 105 2e-23 4XIW-A nrPDB 102 2e-22 4COQ-A nrPDB 102 3e-22 4ETQ-X nrPDB 99 2e-21 6B9J-X nrPDB 99 3e-21 4XZ5-A nrPDB 91 5e-19 4X5S-A nrPDB 89 3e-18 6EKI-A nrPDB 87 1e-17 5HPJ-A nrPDB 83 1e-16 4G7A-A nrPDB 81 7e-16 1KOQ-A nrPDB 76 2e-14 1Y7W-A nrPDB 69 2e-12 4TWL-A nrPDB 67 1e-11 3Q31-A nrPDB 63 1e-10 5TT3-A nrPDB 62 3e-10 3B1B-A nrPDB 57 1e-08 4IZO-A nrPDB 31 0.56 5OHK-A nrPDB 31 0.79 2VKH-A nrPDB 31 0.80 5OHN-A nrPDB 30 0.87 3I2D-A nrPDB 30 1.1 5JNE-A nrPDB 30 1.2 4MKG-A nrPDB 30 1.4 4UM8-B nrPDB 29 2.0 4UM9-D nrPDB 29 2.7 5FZ5-W nrPDB 28 4.6 >3ZNC-A nrPDB Length = 258 Score = 546 bits (1406), Expect = e-156, Method: Compositional matrix adjust. Identities = 257/258 (99%), Positives = 258/258 (100%) Query: 22 WCYEIQTKDPRSSCLGPEKWPGACKENQQSPINIVTARTKVNPRLTPFILVGYDQKQQWP 81 WCYEIQT+DPRSSCLGPEKWPGACKENQQSPINIVTARTKVNPRLTPFILVGYDQKQQWP Sbjct: 1 WCYEIQTEDPRSSCLGPEKWPGACKENQQSPINIVTARTKVNPRLTPFILVGYDQKQQWP 60 Query: 82 IKNNQHTVEMTLGGGACIIGGDLPARYEAVQLHLHWSNGNDNGSEHSIDGRHFAMEMHIV 141 IKNNQHTVEMTLGGGACIIGGDLPARYEAVQLHLHWSNGNDNGSEHSIDGRHFAMEMHIV Sbjct: 61 IKNNQHTVEMTLGGGACIIGGDLPARYEAVQLHLHWSNGNDNGSEHSIDGRHFAMEMHIV 120 Query: 142 HKKLTSSKEDSKDKFAVLAFMIEVGDKVNKGFQPLVEALPSISKPHSTSTVRESSLQDML 201 HKKLTSSKEDSKDKFAVLAFMIEVGDKVNKGFQPLVEALPSISKPHSTSTVRESSLQDML Sbjct: 121 HKKLTSSKEDSKDKFAVLAFMIEVGDKVNKGFQPLVEALPSISKPHSTSTVRESSLQDML 180 Query: 202 PPSTKMYTYFRYNGSLTTPNCDETVIWTVYKQPIKIHKNQFLEFSKNLYYDEDQKLNMKD 261 PPSTKMYTYFRYNGSLTTPNCDETVIWTVYKQPIKIHKNQFLEFSKNLYYDEDQKLNMKD Sbjct: 181 PPSTKMYTYFRYNGSLTTPNCDETVIWTVYKQPIKIHKNQFLEFSKNLYYDEDQKLNMKD 240 Query: 262 NVRPLQPLGKRQVFKSHA 279 NVRPLQPLGKRQVFKSHA Sbjct: 241 NVRPLQPLGKRQVFKSHA 258 >5JN8-A nrPDB Length = 266 Score = 314 bits (804), Expect = 3e-86, Method: Compositional matrix adjust. Identities = 147/265 (55%), Positives = 192/265 (72%), Gaps = 6/265 (2%) Query: 19 DSGWCYEIQTKDPRSSCLGPEKWPGACKENQQSPINIVTARTKVNPRLTPFILVGYDQKQ 78 +S WCYE+Q + CL P KW G C++++QSPINIVT + KV+ +L F GYD+KQ Sbjct: 2 ESHWCYEVQAESSNYPCLVPVKWGGNCQKDRQSPINIVTTKAKVDKKLGRFFFSGYDKKQ 61 Query: 79 QWPIKNNQHTVEMTLGGGACIIGGDLPARYEAVQLHLHWSNGNDNGSEHSIDGRHFAMEM 138 W ++NN H+V M L A I GG LPA Y+A QLHLHWS+ GSEHS+DG HFAMEM Sbjct: 62 TWTVQNNGHSVMMLLENKASISGGGLPAPYQAKQLHLHWSDLPYKGSEHSLDGEHFAMEM 121 Query: 139 HIVHKKLTSSK------EDSKDKFAVLAFMIEVGDKVNKGFQPLVEALPSISKPHSTSTV 192 HIVH+K + +D +D+ AVLAF++E G +VN+GFQPLVEAL +I KP ++T+ Sbjct: 122 HIVHEKEKGTSRNVKEAQDPEDEIAVLAFLVEAGTQVNEGFQPLVEALSNIPKPEMSTTM 181 Query: 193 RESSLQDMLPPSTKMYTYFRYNGSLTTPNCDETVIWTVYKQPIKIHKNQFLEFSKNLYYD 252 ESSL D+LP K+ YFRY GSLTTP CDE V+WTV+++PI++H+ Q L FS+ LYYD Sbjct: 182 AESSLLDLLPKEEKLRHYFRYLGSLTTPTCDEKVVWTVFREPIQLHREQILAFSQKLYYD 241 Query: 253 EDQKLNMKDNVRPLQPLGKRQVFKS 277 ++Q ++MKDNVRPLQ LG+R V KS Sbjct: 242 KEQTVSMKDNVRPLQQLGQRTVIKS 266 >5LL9-A nrPDB Length = 263 Score = 144 bits (363), Expect = 5e-35, Method: Compositional matrix adjust. Identities = 89/250 (35%), Positives = 137/250 (54%), Gaps = 17/250 (6%) Query: 39 EKWPGACKENQQSPINIVTARTKVNPRLTPFILVGYD--QKQQWPIKNNQHTVEMTLGGG 96 +K+P +C QSPI++ + + + LTP GY+ +Q+ + NN H+V++ L Sbjct: 17 KKYP-SCGGLLQSPIDLHSDILQYDASLTPLEFQGYNLSANKQFLLTNNGHSVKLNLPSD 75 Query: 97 ACIIGGDLPARYEAVQLHLHWSNGND-NGSEHSIDGRHFAMEMHIVHKKL-----TSSKE 150 I G L +RY A QLHLHW N ND +GSEH++ G+HFA E+HIVH S+ Sbjct: 76 MHIQG--LQSRYSATQLHLHWGNPNDPHGSEHTVSGQHFAAELHIVHYNSDLYPDASTAS 133 Query: 151 DSKDKFAVLAFMIEVGDKVNKGFQPLVEALPSISKPHSTSTVRESSLQDMLPPSTKMYTY 210 + + AVLA +IE+G N + + L + + V +++++LP T Y Sbjct: 134 NKSEGLAVLAVLIEMG-SFNPSYDKIFSHLQHVKYKGQEAFVPGFNIEELLPERTA--EY 190 Query: 211 FRYNGSLTTPNCDETVIWTVYKQPIKIHKNQFLEFSKNLY---YDEDQKLNMKDNVRPLQ 267 +RY GSLTTP C+ TV+WTV++ P++I + Q L LY D+ M +N R +Q Sbjct: 191 YRYRGSLTTPPCNPTVLWTVFRNPVQISQEQLLALETALYCTHMDDPSPREMINNFRQVQ 250 Query: 268 PLGKRQVFKS 277 +R V+ S Sbjct: 251 KFDERLVYTS 260 >4LU3-A nrPDB Length = 279 Score = 142 bits (359), Expect = 1e-34, Method: Compositional matrix adjust. Identities = 91/253 (35%), Positives = 133/253 (52%), Gaps = 16/253 (6%) Query: 37 GPEKWPGA---CKENQQSPINIVTARTKVNPRLTPFILVGYDQKQQWPIK--NNQHTVEM 91 G + WP + C N QSPI+I T +P L GYDQ P+ NN HTV++ Sbjct: 14 GQDHWPASYPECGNNAQSPIDIQTDSVTFDPDLPALQPHGYDQPGTEPLDLHNNGHTVQL 73 Query: 92 TLGGGACIIGGDLPARYEAVQLHLHWSN-GNDNGSEHSIDGRHFAMEMHIVHKKLTSSKE 150 +L + + G LP +Y A QLHLHW G+ GSEH I+ E+HIVH S Sbjct: 74 SLP--STLYLGGLPRKYVAAQLHLHWGQKGSPGGSEHQINSEATFAELHIVHYDSDSYDS 131 Query: 151 DSK-----DKFAVLAFMIEVGDKVNKGFQPLVEALPSISKPHSTSTVRESSLQDMLPPST 205 S+ AVL +IEVG+ N ++ ++ L + ++V +L+++LP Sbjct: 132 LSEAAERPQGLAVLGILIEVGETKNIAYEHILSHLHEVRHKDQKTSVPPFNLRELLP--K 189 Query: 206 KMYTYFRYNGSLTTPNCDETVIWTVYKQPIKIHKNQFLEFSKNLYYDEDQKLN-MKDNVR 264 ++ YFRYNGSLTTP C ++V+WTV+ + +I Q + L+ E++ + N R Sbjct: 190 QLGQYFRYNGSLTTPPCYQSVLWTVFYRRSQISMEQLEKLQGTLFSTEEEPSKLLVQNYR 249 Query: 265 PLQPLGKRQVFKS 277 LQPL +R VF S Sbjct: 250 ALQPLNQRMVFAS 262 >1RJ5-A nrPDB Length = 261 Score = 134 bits (338), Expect = 4e-32, Method: Compositional matrix adjust. Identities = 90/253 (35%), Positives = 133/253 (52%), Gaps = 16/253 (6%) Query: 37 GPEKWPGA---CKENQQSPINIVTARTKVNPRLTPFILVGYDQKQQWPI--KNNQHTVEM 91 G + WP + C + QSPINI T +P L GYDQ P+ NN HTV++ Sbjct: 12 GQDHWPTSYPECGGDAQSPINIQTDSVIFDPDLPAVQPHGYDQLGTEPLDLHNNGHTVQL 71 Query: 92 TLGGGACIIGGDLPARYEAVQLHLHWSN-GNDNGSEHSIDGRHFAMEMHIVH--KKLTSS 148 +L + G LP +Y A QLHLHW G+ GSEH I+ A E+H+VH + SS Sbjct: 72 SLP--PTLHLGGLPRKYTAAQLHLHWGQRGSLEGSEHHINSEATAAELHVVHYDSQSYSS 129 Query: 149 KEDSKDK---FAVLAFMIEVGDKVNKGFQPLVEALPSISKPHSTSTVRESSLQDMLPPST 205 ++ K AVL +IEVG+ N + ++ L I ++V S++++ P Sbjct: 130 LSEAAQKPQGLAVLGILIEVGETENPAYDHILSRLHEIRYKDQKTSVPPFSVRELFP--Q 187 Query: 206 KMYTYFRYNGSLTTPNCDETVIWTVYKQPIKIHKNQFLEFSKNL-YYDEDQKLNMKDNVR 264 ++ +FRYNGSLTTP C ++V+WTV+ + +I Q + + L +ED + N R Sbjct: 188 QLEQFFRYNGSLTTPPCYQSVLWTVFNRRAQISMGQLEKLQETLSSTEEDPSEPLVQNYR 247 Query: 265 PLQPLGKRQVFKS 277 QPL +R +F S Sbjct: 248 VPQPLNQRTIFAS 260 >5DVX-A nrPDB Length = 260 Score = 134 bits (336), Expect = 7e-32, Method: Compositional matrix adjust. Identities = 86/255 (33%), Positives = 125/255 (49%), Gaps = 16/255 (6%) Query: 37 GPEKWPG---ACKENQQSPINIVTARTKVNPRLTPFILVGYDQKQ--QWPIKNNQHTVEM 91 G WP AC QSP++I +P L P L G+ + ++NN H+V++ Sbjct: 6 GDPPWPRVSPACAGRFQSPVDIRPQLAAFSPALRPLELSGFQLPPLPELRLRNNGHSVQL 65 Query: 92 TLGGGACIIGGDLPAR-YEAVQLHLHWSNGNDNGSEHSIDGRHFAMEMHIVHKKLTSSKE 150 TL G + G P R Y A+QLHLHW GSEH+++G F E+H+VH ++ Sbjct: 66 TLPPGLEMKLG--PGREYRALQLHLHWGAAGRPGSEHTVEGHRFPAEIHVVHLSTKYARV 123 Query: 151 DSK----DKFAVLAFMIEVGDKVNKGFQPLVEALPSISKPHSTSTVRESSLQDMLPPSTK 206 D AVLA +E G + N ++ L+ L I++ S + V + +LP + Sbjct: 124 DEALGRPGGLAVLAAFLEEGPEENSAYEQLLSRLEEIAEEGSETQVPGLDISALLP--SD 181 Query: 207 MYTYFRYNGSLTTPNCDETVIWTVYKQPIKIHKNQFLEFSKNLYYDEDQKLNMKDNVRPL 266 YF+Y GSLTTP C + VIWTV+ Q + + Q S L+ D +L + N R Sbjct: 182 FSRYFQYEGSLTTPPCAQGVIWTVFNQTVSLSAKQLHTLSDTLWGPGDSRLQL--NFRAT 239 Query: 267 QPLGKRQVFKSHAPG 281 QPL R + S G Sbjct: 240 QPLNGRVIEASFPAG 254 >6G4T-A nrPDB Length = 274 Score = 127 bits (318), Expect = 8e-30, Method: Compositional matrix adjust. Identities = 83/250 (33%), Positives = 128/250 (51%), Gaps = 17/250 (6%) Query: 37 GPEKWPG---ACKENQQSPINIVTARTKVNPRLTPFILVGYDQKQQWPIKNNQHTVEMTL 93 GP W + ++QSPINI++++ +P L P L Y+ I NN H+V++ Sbjct: 16 GPSHWHKLYPIAQGDRQSPINIISSQAVYSPSLQPLEL-SYEACMSLSITNNGHSVQVDF 74 Query: 94 GGG---ACIIGGDLPARYEAVQLHLHWSNGNDNGSEHSIDGRHFAMEMHIVH---KKLTS 147 + GG L Y Q H HW +D GSEH++DG+ F E+H+VH KK ++ Sbjct: 75 NDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSELHLVHWNAKKYST 134 Query: 148 SKEDSK--DKFAVLAFMIEVGDKVNKGFQPLVEALPSISKPHSTSTVRESSLQDMLPPST 205 E + D AV+ +E GD+ + L +AL + + + + + +LP S Sbjct: 135 FGEAASAPDGLAVVGVFLETGDE-HPSMNRLTDALYMVRFKGTKAQFSCFNPKSLLPASR 193 Query: 206 KMYTYFRYNGSLTTPNCDETVIWTVYKQPIKIHKNQFLEFSKNLYYDE-DQKLNMKDNVR 264 Y+ Y GSLTTP E+V W V ++PI I + Q +F L+ E D++++M +N R Sbjct: 194 H---YWTYPGSLTTPPLSESVTWIVLREPISISERQMGKFRSLLFTSEDDERIHMVNNFR 250 Query: 265 PLQPLGKRQV 274 P QPL R V Sbjct: 251 PPQPLKGRVV 260 >3FE4-A nrPDB Length = 278 Score = 126 bits (317), Expect = 9e-30, Method: Compositional matrix adjust. Identities = 89/275 (32%), Positives = 138/275 (50%), Gaps = 18/275 (6%) Query: 20 SGWCYEIQTKDPRSSCLGPEKWPGACKENQQSPINIVTARTKVNPRLTPFILVGYD-QKQ 78 S W Y D P+ +P AC +QSPIN+ + + NP L + GY+ Q Sbjct: 2 SDWTYSEGALD---EAHWPQHYP-ACGGQRQSPINLQRTKVRYNPSLKGLNMTGYETQAG 57 Query: 79 QWPIKNNQHTVEMTLGGGACIIGGDLPARYEAVQLHLHWSNGND--NGSEHSIDGRHFAM 136 ++P+ NN HTV+++L + D Y A Q+H HW + +GSEH++DG + Sbjct: 58 EFPMVNNGHTVQISLPSTMRMTVADGTV-YIAQQMHFHWGGASSEISGSEHTVDGIRHVI 116 Query: 137 EMHIVHK----KLTSSKEDSKDKFAVLAFMIEVGDK-VNKGFQPLVEALPSISKPHSTST 191 E+HIVH K +D+ D AVLA +EV + N + + L +I P +T Sbjct: 117 EIHIVHYNSKYKSYDIAQDAPDGLAVLAAFVEVKNYPENTYYSNFISHLANIKYPGQRTT 176 Query: 192 VRESSLQDMLPPSTKMYTYFRYNGSLTTPNCDETVIWTVYKQPIKIHKNQFLEFSKNLYY 251 + +QDMLP + + Y + Y+GSLTTP C E V W V +K+ + Q + +L Sbjct: 177 LTGLDVQDMLPRNLQHY--YTYHGSLTTPPCTENVHWFVLADFVKLSRTQVWKLENSLL- 233 Query: 252 DEDQKLNMKDNVRPLQPLGKRQVFKSHAPGQLLSL 286 + + + ++ R QPL R V +S+ P Q +L Sbjct: 234 -DHRNKTIHNDYRRTQPLNHR-VVESNFPNQEYTL 266 >4QK3-A nrPDB Length = 249 Score = 125 bits (313), Expect = 3e-29, Method: Compositional matrix adjust. Identities = 85/248 (34%), Positives = 114/248 (45%), Gaps = 25/248 (10%) Query: 37 GPEKWPG---ACKENQQSPINIVTARTKVNPRLTPFILVGYDQKQQWPIKNNQHTVEMTL 93 GPE W K +QSP++I T K +P L P + V YDQ I NN H + Sbjct: 12 GPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKP-LSVSYDQATSLRILNNGHAFNVEF 70 Query: 94 GGG---ACIIGGDLPARYEAVQLHLHWSNGNDNGSEHSIDGRHFAMEMHIVHKKLT---- 146 A + GG L Y +Q H HW + + GSEH++D + +A E+H+VH Sbjct: 71 DDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDF 130 Query: 147 SSKEDSKDKFAVLAFMIEVGDKVNKGFQPLVEALPSISKPHSTSTVRESSLQDMLPPSTK 206 D AVL ++VG G Q +V+ L SI ++ + +LP S Sbjct: 131 GKAVQQPDGLAVLGIFLKVG-SAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESL- 188 Query: 207 MYTYFRYNGSLTTPNCDETVIWTVYKQPIKIHKNQFLEFSKNLYYDEDQKLNMKDNVRPL 266 Y+ Y GSLTTP E V W V K+PI + Q L+F K M DN RP Sbjct: 189 --DYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRK----------LMVDNWRPA 236 Query: 267 QPLGKRQV 274 QPL RQ+ Sbjct: 237 QPLKNRQI 244 >1Z93-A nrPDB Length = 266 Score = 120 bits (302), Expect = 6e-28, Method: Compositional matrix adjust. Identities = 82/253 (32%), Positives = 125/253 (49%), Gaps = 18/253 (7%) Query: 37 GPEKW----PGACKENQQSPINIVTARTKVNPRLTPFILVGYDQKQQWPIKNNQHTVEMT 92 GP+ W P A ENQ SPI + T + +P L P+ V YD I NN T + Sbjct: 12 GPDHWHELFPNAKGENQ-SPIELHTKDIRHDPSLQPWS-VSYDGGSAKTILNNGKTCRVV 69 Query: 93 LGGG---ACIIGGDLPARYEAVQLHLHWSNGNDNGSEHSIDGRHFAMEMHIVH--KKLTS 147 + + GG LP Y Q HLHW + +D+GSEH++DG +A E+H+VH K + Sbjct: 70 FDDTYDRSMLRGGPLPGPYRLRQFHLHWGSSDDHGSEHTVDGVKYAAELHLVHWNPKYNT 129 Query: 148 SKE--DSKDKFAVLAFMIEVGDKVNKGFQPLVEALPSISKPHSTSTVRESSLQDMLPPST 205 KE +D AV+ +++G + N FQ ++AL I + + + P S Sbjct: 130 FKEALKQRDGIAVIGIFLKIGHE-NGEFQIFLDALDKIKTKGKEAPFTKFDPSSLFPASR 188 Query: 206 KMYTYFRYNGSLTTPNCDETVIWTVYKQPIKIHKNQFLEFSKNLYYDEDQ-KLNMKDNVR 264 Y+ Y GS TTP C+E ++W + K+P+ + +Q + L E++ + + N R Sbjct: 189 D---YWTYQGSFTTPPCEECIVWLLLKEPMTVSSDQMAKLRSLLSSAENEPPVPLVSNWR 245 Query: 265 PLQPLGKRQVFKS 277 P QP+ R V S Sbjct: 246 PPQPINNRVVRAS 258 >3D0N-A nrPDB Length = 264 Score = 119 bits (298), Expect = 1e-27, Method: Compositional matrix adjust. Identities = 83/239 (34%), Positives = 117/239 (48%), Gaps = 14/239 (5%) Query: 48 NQQSPINIVTARTKVNPRLTPFILVGYDQKQQWPIKNNQHTVEMTLG---GGACIIGGDL 104 +QQSPI I T K + L P + + YD I N+ H+ + + + GG L Sbjct: 29 DQQSPIEIKTKEVKYDSSLRP-LSIKYDPSSAKIISNSGHSFNVDFDDTENKSVLRGGPL 87 Query: 105 PARYEAVQLHLHWSNGNDNGSEHSIDGRHFAMEMHIVH---KKLTSSKEDSK--DKFAVL 159 Y Q+HLHW + +D+GSEH +DG +A E+H+VH K S E + D AVL Sbjct: 88 TGSYRLRQVHLHWGSADDHGSEHIVDGVSYAAELHVVHWNSDKYPSFVEAAHEPDGLAVL 147 Query: 160 AFMIEVGDKVNKGFQPLVEALPSISKPHSTSTVRESSLQDMLPPSTKMYTYFRYNGSLTT 219 +++G+ N Q + + L SI + + L +LPPS + Y+ Y GSLT Sbjct: 148 GVFLQIGEP-NSQLQKITDTLDSIKEKGKQTRFTNFDLLSLLPPS---WDYWTYPGSLTV 203 Query: 220 PNCDETVIWTVYKQPIKIHKNQFLEFSKNLYYDEDQKLN-MKDNVRPLQPLGKRQVFKS 277 P E+V W V KQPI I Q +F L E + + N RP QPL R+V S Sbjct: 204 PPLLESVTWIVLKQPINISSQQLAKFRSLLCTAEGEAAAFLVSNHRPPQPLKGRKVRAS 262 >4CNR-A nrPDB Length = 262 Score = 116 bits (290), Expect = 1e-26, Method: Compositional matrix adjust. Identities = 84/252 (33%), Positives = 123/252 (48%), Gaps = 22/252 (8%) Query: 37 GPEKW----PGACKENQQSPINIVTARTKVNPRLTPFILVGYDQKQQWPIKNNQHTVEMT 92 GPE W P A E +QSP++I T +P L P L Y + + N+ H+ + Sbjct: 14 GPEHWHKDFPIANGE-RQSPVDIDTDAVVQDPALKPLAL-DYGEATSRRMVNDGHSFNVE 71 Query: 93 LGGG---ACIIGGDLPARYEAVQLHLHWSNGNDNGSEHSIDGRHFAMEMHIVHKKL---- 145 A + G L Y VQ H HW + +D GSEH++D + +A E+H+VH Sbjct: 72 YDDSQDKAVLKDGPLTGTYRLVQFHFHWGSSDDQGSEHTVDRKKYAAELHLVHWNTKYGD 131 Query: 146 --TSSKEDSKDKFAVLAFMIEVGDKVNKGFQPLVEALPSISKPHSTSTVRESSLQDMLPP 203 T+++E D AV+ ++VGD N Q +++AL SI ++ +LP Sbjct: 132 FGTAAQE--PDGLAVVGVFLKVGD-ANPALQKVLDALDSIKTKGKSTDFPNFDPGSLLP- 187 Query: 204 STKMYTYFRYNGSLTTPNCDETVIWTVYKQPIKIHKNQFLEFSK-NLYYDEDQKLNMKDN 262 + Y+ Y GSLTTP E+V W V K+PI + Q L+F N + + + M N Sbjct: 188 --NVLDYWTYPGSLTTPPLLESVTWIVLKEPISVSSQQMLKFRTLNFNAEGEPEELMLAN 245 Query: 263 VRPLQPLGKRQV 274 RP QPL RQV Sbjct: 246 WRPAQPLKNRQV 257 >6FAF-A nrPDB Length = 261 Score = 111 bits (277), Expect = 4e-25, Method: Compositional matrix adjust. Identities = 80/253 (31%), Positives = 120/253 (47%), Gaps = 17/253 (6%) Query: 37 GPEKWPG---ACKENQQSPINIVTARTKVNPRLTPFILVGYDQKQQWPIKNNQHTVEMTL 93 GPE+W N QSP++I T+ TK + L P I V Y+ I N H+ + Sbjct: 13 GPEQWSKLYPIANGNNQSPVDIKTSETKHDTSLKP-ISVSYNPATAKEIINVGHSFHVNF 71 Query: 94 GGG---ACIIGGDLPARYEAVQLHLHWSNGNDNGSEHSIDGRHFAMEMHIVH---KKLTS 147 + + GG Y Q H HW + N++GSEH++DG ++ E+H+ H K +S Sbjct: 72 EDNDNRSVLKGGPFSDSYRLFQFHFHWGSTNEHGSEHTVDGVKYSAELHVAHWNSAKYSS 131 Query: 148 SKEDSK--DKFAVLAFMIEVGDKVNKGFQPLVEALPSISKPHSTSTVRESSLQDMLPPST 205 E + D AV+ +++VG+ N Q +++AL +I + +LP S Sbjct: 132 LAEAASKADGLAVIGVLMKVGE-ANPKLQKVLDALQAIKTKGKRAPFTNFDPSTLLPSSL 190 Query: 206 KMYTYFRYNGSLTTPNCDETVIWTVYKQPIKIHKNQFLEFSKNLYYDE-DQKLNMKDNVR 264 +T Y GSLT P E+V W + K+ I + Q +F L E D + M+ N R Sbjct: 191 DFWT---YPGSLTHPPLYESVTWIICKESISVSSEQLAQFRSLLSNVEGDNAVPMQHNNR 247 Query: 265 PLQPLGKRQVFKS 277 P QPL R V S Sbjct: 248 PTQPLKGRTVRAS 260 >1FLJ-A nrPDB Length = 260 Score = 108 bits (271), Expect = 2e-24, Method: Compositional matrix adjust. Identities = 79/253 (31%), Positives = 122/253 (48%), Gaps = 18/253 (7%) Query: 37 GPEKW----PGACKENQQSPINIVTARTKVNPRLTPFILVGYDQKQQWPIKNNQHTVEMT 92 GPE W P A K + QSPI + T + +P L P+ V YD I NN T + Sbjct: 12 GPEHWHELYPIA-KGDNQSPIELHTKDIRHDPSLQPWS-VSYDPGSAKTILNNGKTCRVV 69 Query: 93 LGGG---ACIIGGDLPARYEAVQLHLHWSNGNDNGSEHSIDGRHFAMEMHIVH--KKLTS 147 + + GG L Y Q HLHW + +D+GSEH++DG +A E+H+VH K + Sbjct: 70 FDDTFDRSMLRGGPLSGPYRLRQFHLHWGSSDDHGSEHTVDGVKYAAELHLVHWNPKYNT 129 Query: 148 SKEDSK--DKFAVLAFMIEVGDKVNKGFQPLVEALPSISKPHSTSTVRESSLQDMLPPST 205 E K D AV+ +++G + + FQ L++AL I + + P Sbjct: 130 FGEALKQPDGIAVVGIFLKIGREKGE-FQILLDALDKIKTKGKEAPFNHFDPSCLFPACR 188 Query: 206 KMYTYFRYNGSLTTPNCDETVIWTVYKQPIKIHKNQFLEFSKNLYYDEDQ-KLNMKDNVR 264 Y+ Y+GS TTP C+E ++W + K+P+ + +Q + E++ + + N R Sbjct: 189 D---YWTYHGSFTTPPCEECIVWLLLKEPMTVSSDQMAKLRSLFASAENEPPVPLVGNWR 245 Query: 265 PLQPLGKRQVFKS 277 P QP+ R V S Sbjct: 246 PPQPIKGRVVRAS 258 >2W2J-A nrPDB Length = 291 Score = 107 bits (268), Expect = 4e-24, Method: Compositional matrix adjust. Identities = 71/243 (29%), Positives = 123/243 (50%), Gaps = 24/243 (9%) Query: 50 QSPINIVTARTKVNP-----RLTPFILVGYDQKQQWPIKNNQHTVEMTLGGGACIIGGDL 104 QSPIN+ + + +P RL+P +V D + + N+ HT+++ L + + GG L Sbjct: 50 QSPINLNSREARYDPSLLDVRLSPNYVVCRDCE----VTNDGHTIQVILKSKSVLSGGPL 105 Query: 105 PA--RYEAVQLHLHWSNGNDNGSEHSIDGRHFAMEMHIVH--KKLTSSKEDSKDK---FA 157 P +E ++ HW N GSEH+++ + F ME+H++H L S +++ K A Sbjct: 106 PQGHEFELYEVRFHWGRENQRGSEHTVNFKAFPMELHLIHWNSTLFGSIDEAVGKPHGIA 165 Query: 158 VLAFMIEVGDKVNKGFQPLVEALPSISKPHSTSTVRESSLQDMLPPSTKMYTYFRYNGSL 217 ++A +++G K + G + + E L I + T+ + +L P + Y+ Y GSL Sbjct: 166 IIALFVQIG-KEHVGLKAVTEILQDIQYKGKSKTIPCFNPNTLL-PDPLLRDYWVYEGSL 223 Query: 218 TTPNCDETVIWTVYKQPIKIHKNQFLEFSKNLYYDEDQKLN------MKDNVRPLQPLGK 271 T P C E V W +++ P+ I + Q EF + + + +L + DN RP QPL Sbjct: 224 TIPPCSEGVTWILFRYPLTISQLQIEEFRRLRTHVKGAELVEGCDGILGDNFRPTQPLSD 283 Query: 272 RQV 274 R + Sbjct: 284 RVI 286 >1URT-A nrPDB Length = 248 Score = 105 bits (262), Expect = 2e-23, Method: Compositional matrix adjust. Identities = 71/243 (29%), Positives = 117/243 (48%), Gaps = 14/243 (5%) Query: 44 ACKENQQSPINIVTARTKVNPRLTPFILVGYDQKQQWPIKNNQHTVEMTLGGG---ACII 100 + + +QSPINI + +P+L P + V YD + N H ++ + I Sbjct: 1 SAEGTRQSPINIQWKDSVYDPQLAP-LRVSYDAASCRYLWNTGHAFQVEFDDSCEDSGIS 59 Query: 101 GGDLPARYEAVQLHLHWSNGNDNGSEHSIDGRHFAMEMHIVHKKLTSSKEDSK-----DK 155 GG L Y Q H HW ++ GSEH++DG + E+H+VH T + K + Sbjct: 60 GGPLGNHYRLKQFHFHWGATDEWGSEHAVDGHTYPAELHLVHWNSTKYENYKKASVGENG 119 Query: 156 FAVLAFMIEVGDKVNKGFQPLVEALPSISKPHSTSTVRESSLQDMLPPSTKMYTYFRYNG 215 AV+ +++G ++ Q LV+ LP + + + + ++P Y+ Y G Sbjct: 120 LAVIGVFLKLGAH-HQALQKLVDVLPEVRHKDTQVAMGDFDPSCLMPACRD---YWTYPG 175 Query: 216 SLTTPNCDETVIWTVYKQPIKIHKNQFLEFSKNLYYDEDQKLN-MKDNVRPLQPLGKRQV 274 SLTTP E+V W V K P+++ +Q F L+ ++ + M +N RPLQPL R++ Sbjct: 176 SLTTPPLAESVTWIVQKTPVEVSPSQLSMFRTLLFSGRGEEEDVMVNNYRPLQPLRDRKL 235 Query: 275 FKS 277 S Sbjct: 236 RSS 238 >4XIW-A nrPDB Length = 239 Score = 102 bits (255), Expect = 2e-22, Method: Compositional matrix adjust. Identities = 82/245 (33%), Positives = 114/245 (46%), Gaps = 27/245 (11%) Query: 37 GPEKWPGACKEN-QQSPINIV--TARTKVNPRLTPFILVGYDQKQQWPIKNNQH-TVEMT 92 GP W G C +QSPINI T+ KV+ + F Y ++ + N H T+++ Sbjct: 11 GPPTWKGVCATGKRQSPINIPLNTSAPKVDAEMGEFDFA-YGSFEKCDVLNTGHGTMQVN 69 Query: 93 LGGGACIIGGDLPARYEAVQLHLHWSNGNDNGSEHSIDGRHFAMEMHIVHKKLTSSKEDS 152 G G++ E +Q H H SEH++DGR +AME H+VHK S Sbjct: 70 FPAGNLAFIGNM--ELELLQFHFHAP------SEHAMDGRRYAMEAHLVHKN------KS 115 Query: 153 KDKFAVLAFMIEVGDKV-NKGFQPLVEALPSISKPHSTSTVRESSLQDMLPPSTKMYT-- 209 AVL M+E G + N +E P + S + + +LP +K T Sbjct: 116 TGNLAVLGIMLEPGGLIKNPALSTALEVAPEVPLAKKPSPKGINPVM-LLPKKSKAGTRP 174 Query: 210 YFRYNGSLTTPNCDETVIWTVYKQPIKIHKNQFLEFSKNLYYDEDQKLNMKDNVRPLQPL 269 + Y GSLTTP C E V W V+ QPIK+ +Q L+F + + D K N RPLQ L Sbjct: 175 FVHYPGSLTTPPCSEGVDWFVFMQPIKVPDSQILDFMR---FVGDNK-TYATNTRPLQLL 230 Query: 270 GKRQV 274 R V Sbjct: 231 NSRLV 235 >4COQ-A nrPDB Length = 247 Score = 102 bits (253), Expect = 3e-22, Method: Compositional matrix adjust. Identities = 81/254 (31%), Positives = 120/254 (47%), Gaps = 45/254 (17%) Query: 33 SSCLGPEKWPGACKE-------NQQSPINIVTARTKVNPRLTPFILVGYDQKQQWPIKNN 85 S +GPE W E QSPI+I +A V L P + V Y ++ + NN Sbjct: 29 SGSIGPEHWGDLSPEYLMCKIGKNQSPIDINSADA-VKACLAP-VSVYYVSDAKY-VVNN 85 Query: 86 QHTVEMTLGG-GACIIGGDLPARYEAVQLHLHWSNGNDNGSEHSIDGRHFAMEMHIVHKK 144 HT+++ +GG G ++ G R+ Q H H SEH+++G+H+ E H VH Sbjct: 86 GHTIKVVMGGRGYVVVDGK---RFYLKQFHFHAP------SEHTVNGKHYPFEAHFVHL- 135 Query: 145 LTSSKEDSKDKFAVLAFMIEVGDKVNKGFQPLVEALPSI--SKPHSTSTVRESSLQDMLP 202 D VL +VG K N + + +P K H T+ + L LP Sbjct: 136 ------DKNGNITVLGVFFKVG-KENPELEKVWRVMPEEPGQKRHLTARIDPEKL---LP 185 Query: 203 PSTKMYTYFRYNGSLTTPNCDETVIWTVYKQPIKIHKNQFLEFSKNLYYDEDQKLNMKDN 262 + Y+RY+GSLTTP C E V W V+K+P+++ + Q +F K + + DN Sbjct: 186 ENR---DYYRYSGSLTTPPCSEGVRWIVFKEPVEMSREQLEKFRKVMGF---------DN 233 Query: 263 VRPLQPLGKRQVFK 276 RP+QPL R+V K Sbjct: 234 NRPVQPLNARKVMK 247 >4ETQ-X nrPDB Length = 269 Score = 99.0 bits (245), Expect = 2e-21, Method: Compositional matrix adjust. Identities = 69/202 (34%), Positives = 102/202 (50%), Gaps = 11/202 (5%) Query: 49 QQSPINIVTARTKVNPRLTPFILVGYDQKQQWPIKNNQHTVEMTLGGGACIIGGDLPARY 108 Q SPINI T + N RL P + + Y++ + I+N V + GG I GG LP Y Sbjct: 4 QLSPINIETKKAISNARLKP-LDIHYNESKPTTIQNTGKLVRINFKGG-YISGGFLPNEY 61 Query: 109 EAVQLHLHWSNGNDNGSEHSIDGRHFAMEMHIVH--KKLTSSKEDSK---DKFAVLAFMI 163 LH++W +D GS H ID ++ E+++VH KK SS E++K D +++ + Sbjct: 62 VLSSLHIYWGKEDDYGSNHLIDVYKYSGEINLVHWNKKKYSSYEEAKKHDDGLIIISIFL 121 Query: 164 EVGDKVNKGFQPLVEALPSISKPHSTSTVRESSLQDMLPPSTKMYTYFRYNGSLTTPNCD 223 +V D N FQ +V L SI ++++ D L PS YF Y G TT N Sbjct: 122 QVLDHKNVYFQKIVNQLDSIRSANTSAPFDSVFYLDNLLPSK--LDYFTYLG--TTINHS 177 Query: 224 ETVIWTVYKQPIKIHKNQFLEF 245 +W ++ PI IH +Q +F Sbjct: 178 ADAVWIIFPTPINIHSDQLSKF 199 >6B9J-X nrPDB Length = 241 Score = 98.6 bits (244), Expect = 3e-21, Method: Compositional matrix adjust. Identities = 69/202 (34%), Positives = 102/202 (50%), Gaps = 11/202 (5%) Query: 49 QQSPINIVTARTKVNPRLTPFILVGYDQKQQWPIKNNQHTVEMTLGGGACIIGGDLPARY 108 Q SPINI T + N RL P + + Y++ + I+N V + GG I GG LP Y Sbjct: 4 QLSPINIETKKAISNARLKP-LDIHYNESKPTTIQNTGKLVRINFKGG-YISGGFLPNEY 61 Query: 109 EAVQLHLHWSNGNDNGSEHSIDGRHFAMEMHIVH--KKLTSSKEDSK---DKFAVLAFMI 163 LH++W +D GS H ID ++ E+++VH KK SS E++K D +++ + Sbjct: 62 VLSSLHIYWGKEDDYGSNHLIDVYKYSGEINLVHWNKKKYSSYEEAKKHDDGLIIISIFL 121 Query: 164 EVGDKVNKGFQPLVEALPSISKPHSTSTVRESSLQDMLPPSTKMYTYFRYNGSLTTPNCD 223 +V D N FQ +V L SI ++++ D L PS YF Y G TT N Sbjct: 122 QVLDHKNVYFQKIVNQLDSIRSANTSAPFDSVFYLDNLLPSK--LDYFTYLG--TTINHS 177 Query: 224 ETVIWTVYKQPIKIHKNQFLEF 245 +W ++ PI IH +Q +F Sbjct: 178 ADAVWIIFPTPINIHSDQLSKF 199 >4XZ5-A nrPDB Length = 233 Score = 91.3 bits (225), Expect = 5e-19, Method: Compositional matrix adjust. Identities = 79/249 (31%), Positives = 110/249 (44%), Gaps = 40/249 (16%) Query: 37 GPEKWP------GACKENQ-QSPINIVTARTKVNPRLTPFILVGYDQKQQWPIKNNQHTV 89 GP+ W CK + QSPIN+ +T V P V Y ++ + NN HT+ Sbjct: 11 GPQYWGELAPEFSTCKTGKNQSPINL-KPQTAVGTTSLPGFDV-YYRETALKLINNGHTL 68 Query: 90 EMTLGGGACI-IGGDLPARYEAVQLHLHWSNGNDNGSEHSIDGRHFAMEMHIVHKKLTSS 148 ++ + G+ I I G RYE +Q H H SEH DG ++ MEMH+VHK Sbjct: 69 QVNIPLGSYIKINGH---RYELLQYHFH------TPSEHQRDGFNYPMEMHLVHK----- 114 Query: 149 KEDSKDKFAVLAFMIEVGDKVNKGFQPLVEALPSISKPHSTSTVRESSLQDMLPPSTKMY 208 D AV+A + + G++ N+ L+ LP K + P K Y Sbjct: 115 --DGDGNLAVIAILFQEGEE-NETLAKLMSFLPQTLKKQEIHESVKIHPAKFFPADKKFY 171 Query: 209 TYFRYNGSLTTPNCDETVIWTVYKQPIKIHKNQFLEFSKNLYYDEDQKLNMKDNVRPLQP 268 +Y+GSLTTP C E V W V+KQPI+ Q E + N RP+Q Sbjct: 172 ---KYSGSLTTPPCSEGVYWMVFKQPIQASVTQL----------EKMHEYLGSNARPVQR 218 Query: 269 LGKRQVFKS 277 R + KS Sbjct: 219 QNARTLLKS 227 >4X5S-A nrPDB Length = 232 Score = 88.6 bits (218), Expect = 3e-18, Method: Compositional matrix adjust. Identities = 77/265 (29%), Positives = 115/265 (43%), Gaps = 52/265 (19%) Query: 22 WCYEIQTKDPRSSCLGPEKWPGACKENQQSPINIVTARTKVNPRLTPFILVGYDQKQQWP 81 W YE + + L PE + C QSP++I + KV+ +L + + Y++ Sbjct: 10 WSYEGENGPENWAKLNPEYF--WCNLKNQSPVDI-SDNYKVHAKLEK-LHINYNKAVNPE 65 Query: 82 IKNNQHTVEMT-LGGGACIIGGDLPARYEAVQLHLHWSNGNDNGSEHSIDGRHFAMEMHI 140 I NN HT+++ L I G Y Q H H SEH+++G+++ +EMH+ Sbjct: 66 IVNNGHTIQVNVLEDFKLNIKG---KEYHLKQFHFHAP------SEHTVNGKYYPLEMHL 116 Query: 141 VHKKLTSSKEDSKDKFAVLAFMIEVGDKVNKGFQPLVEALPSISKPHSTSTVRESS---- 196 VHK D AV+ + G +A P + K + E S Sbjct: 117 VHK-------DKDGNIAVIGVFFKEG-----------KANPELDKVFKNALKEEGSKVFD 158 Query: 197 ----LQDMLPPSTKMYTYFRYNGSLTTPNCDETVIWTVYKQPIKIHKNQFLEFSKNLYYD 252 + +LPP YTY +GSLTTP C E V+W V KQPI K Q F Sbjct: 159 GSININALLPPVKNYYTY---SGSLTTPPCTEGVLWIVLKQPITASKQQIELF------- 208 Query: 253 EDQKLNMKDNVRPLQPLGKRQVFKS 277 + + +N RP QP+ R + +S Sbjct: 209 --KSIMKHNNNRPTQPINSRYILES 231 >6EKI-A nrPDB Length = 226 Score = 86.7 bits (213), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 76/262 (29%), Positives = 116/262 (44%), Gaps = 50/262 (19%) Query: 22 WCYEIQTKDPRSSCLGPEKWPG------ACKENQ-QSPINIVTARTKVNPRLTPFILVGY 74 W Y +T GP+ W CK + QSP++I +++ I + Y Sbjct: 6 WSYHGET--------GPQHWGDLKNEYIMCKIGKNQSPVDI----SRIVEAELEKIKINY 53 Query: 75 DQKQQWPIKNNQHTVEMTLGGGACIIGGDLPARYEAVQLHLHWSNGNDNGSEHSIDGRHF 134 I NN HT++++ G+ II + R+E Q H H SEH+I G+ + Sbjct: 54 SSGGS-SITNNGHTIKVSYEPGSYIIVDGI--RFELKQFHFHAP------SEHTIKGKSY 104 Query: 135 AMEMHIVHKKLTSSKEDSKDKFAVLAFMIEVGDKVNKGFQPLVEALPSISKPHSTSTVRE 194 E H VH D AV+ + + G K N + + E LP K + + Sbjct: 105 PFEAHFVHA-------DKDGNLAVIGVIFKEGKK-NPIIEKIWENLPEAGK--TIKLAHK 154 Query: 195 SSLQDMLPPSTKMYTYFRYNGSLTTPNCDETVIWTVYKQPIKIHKNQFLEFSKNLYYDED 254 + D+LP K Y+RY+GSLTTP C E V W V ++ +++ K Q +F Sbjct: 155 INAYDLLPKKKK---YYRYSGSLTTPPCSEGVRWIVMEEEMELSKEQIEKF--------- 202 Query: 255 QKLNMKDNVRPLQPLGKRQVFK 276 +KL D RP+QPL R + + Sbjct: 203 RKLMGGDTNRPVQPLNARMIME 224 >5HPJ-A nrPDB Length = 217 Score = 83.2 bits (204), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 73/246 (29%), Positives = 109/246 (44%), Gaps = 43/246 (17%) Query: 37 GPEKWP---GACKEN-QQSPINIVTARTKVNPRLTPFILVGYDQKQQWPIKNNQHTVEMT 92 G E W C E Q+PI+I L P L Q + + NN HT++ Sbjct: 9 GTEHWGDSFATCAEGVNQTPIDI---NQTTQAELAPLHLDYEGQVTE--LVNNGHTIQAN 63 Query: 93 LGGGACI-IGGDLPARYEAVQLHLHWSNGNDNGSEHSIDGRHFAMEMHIVHKKLTSSKED 151 L G + + G +E Q H H SE+ + G+ + +E H VH Sbjct: 64 LTGKNTLTVDGK---TFELKQFHFH------TPSENYLKGKQYPLEAHFVHAT------- 107 Query: 152 SKDKFAVLAFMIEVGDKVNKGFQPLVEALPSISKPHSTSTVRES-SLQDMLPPSTKMYTY 210 K + AV+A M + G + N L+ ++PS + T ++E+ + D+LP + Y Sbjct: 108 DKGELAVVAVMFDFGPRSNNELTTLLASIPSKGQ---TVELKEALNPADLLPRDRE---Y 161 Query: 211 FRYNGSLTTPNCDETVIWTVYKQPIKIHKNQFLEFSKNLYYDEDQKLNMKDNVRPLQPLG 270 +R+NGSLTTP C E V W V ++P K Q E + M +N RPLQPL Sbjct: 162 YRFNGSLTTPPCSEGVRWFVMQEPQTSSKAQ----------TEKLQAVMGNNARPLQPLN 211 Query: 271 KRQVFK 276 R + + Sbjct: 212 ARLILE 217 >4G7A-A nrPDB Length = 248 Score = 80.9 bits (198), Expect = 7e-16, Method: Compositional matrix adjust. Identities = 74/256 (28%), Positives = 117/256 (45%), Gaps = 34/256 (13%) Query: 22 WCYEIQTKDPRSSCLGPEKWPGACKENQQSPINIVTARTKVNPRLTPFILVGYDQKQQWP 81 W YE + + L PE + CK QSPINI + KV L P + + Y ++ Sbjct: 26 WSYEGEKGPEHWAQLKPEFF--WCKLKNQSPINI-DKKYKVKANL-PKLNLYYKTAKESE 81 Query: 82 IKNNQHTVEMTLGGGACIIGGDLPARYEAVQLHLHWSNGNDNGSEHSIDGRHFAMEMHIV 141 + NN HT+++ + + L +Y+ Q H H SEH+I+ + + +E+H V Sbjct: 82 VVNNGHTIQINIKEDNTL--NYLGEKYQLKQFHFH------TPSEHTIEKKSYPLEIHFV 133 Query: 142 HKKLTSSKEDSKDKFAVLAFMIEVGDKVNKGFQPLVEALPSISKPHSTSTVRESSLQDML 201 HK ED K V+ M ++G K NK ++ P+ + ++ + L Sbjct: 134 HKT-----EDGK--ILVVGVMAKLG-KTNKELDKILNVAPA---EEGEKILDKNLNLNNL 182 Query: 202 PPSTKMYTYFRYNGSLTTPNCDETVIWTVYKQPIKIHKNQFLEFSKNLYYDEDQKLNMKD 261 P K Y Y+GSLTTP C E V W V K+PI I K Q ++ + + + Sbjct: 183 IPKDK--RYMTYSGSLTTPPCTEGVRWIVLKKPISISKQQL---------EKLKSVMVNP 231 Query: 262 NVRPLQPLGKRQVFKS 277 N RP+Q + R + + Sbjct: 232 NNRPVQEINSRWIIEG 247 >1KOQ-A nrPDB Length = 223 Score = 76.3 bits (186), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 77/254 (30%), Positives = 107/254 (42%), Gaps = 57/254 (22%) Query: 38 PEKWPGACKE-------NQQSPINIVTARTKVNPRLTPFILVGYDQKQQWPIKNNQHTVE 90 PE W +E QSP+NI V+ +L P I V Y + ++NN HT++ Sbjct: 12 PESWGNLSEEFRLCSTGKNQSPVNITET---VSGKL-PAIKVNY-KPSMVDVENNGHTIQ 66 Query: 91 MTL--GGGACIIGGDLPARYEAVQLHLHWSNGNDNGSEHSIDGRHFAMEMHIVHKKLTSS 148 + GG + G Y Q H H SE+ I GR F ME H VH Sbjct: 67 VNYPEGGNTLTVNGRT---YTLKQFHFHVP------SENQIKGRTFPMEAHFVHL----- 112 Query: 149 KEDSKDKFAVLAFMIEVGDKVNKGFQPLVEALP------SISKPHSTSTVRESSLQDMLP 202 D + VLA + E G K N + +P +++P ST +LP Sbjct: 113 --DENKQPLVLAVLYEAG-KTNGRLSSIWNVMPMTAGKVKLNQPFDAST--------LLP 161 Query: 203 PSTKMYTYFRYNGSLTTPNCDETVIWTVYKQPIKIHKNQFLEFSKNLYYDEDQKLNMKDN 262 K Y+R+ GSLTTP C E V W V K I + Q +F++ + +N Sbjct: 162 ---KRLKYYRFAGSLTTPPCTEGVSWLVLKTYDHIDQAQAEKFTRAV---------GSEN 209 Query: 263 VRPLQPLGKRQVFK 276 RP+QPL R V + Sbjct: 210 NRPVQPLNARVVIE 223 >1Y7W-A nrPDB Length = 291 Score = 68.9 bits (167), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 71/266 (26%), Positives = 114/266 (42%), Gaps = 42/266 (15%) Query: 37 GPEKWPGACKENQQSPINIVTAR-----TKVNPRLTPFILVGYDQKQQWPIKNNQHTVEM 91 G K+P AC + QSPI+I T + ++ + D Q I V++ Sbjct: 39 GTTKYP-ACSGSNQSPIDINTNQLMEPSSRSGTSAVSLNGLNVDGAQADGITLTNAKVDL 97 Query: 92 TLGGGACI-----------IGGDLPARYEAVQLHLHWSNGNDNGSEHSIDGRHFAMEMHI 140 G IGG + + +Q H H SEH+I+G H+ +E+HI Sbjct: 98 EQGMKVTFDQPAANLPTIEIGGTTKS-FVPIQFHFHHFL-----SEHTINGIHYPLELHI 151 Query: 141 VHKKLTSSKEDSKDKFAVLAFMI---EVGDKVNKGFQPLVEA-LPSISKPHSTSTVRESS 196 V ++ + + + AV+ M E GD Q +E + + + + V + Sbjct: 152 VMQE-QDPADVATAQLAVIGIMYKYSENGDAFLNSLQTQIEGKIGDGTASYGDTGVSIDN 210 Query: 197 LQ---DMLPPSTKMYTYFRYNGSLTTPNCDETVIWTVYKQPIKIHKNQ---FLEFSKNLY 250 + +LP S K Y Y+GSLTTP CDE V W V+ P ++ + Q F++ + + Sbjct: 211 INVKTQLLPSSLK---YAGYDGSLTTPGCDERVKWHVFTTPREVTREQMKLFVDVTMGAH 267 Query: 251 YDEDQKLNMKDNVRPLQPLGKRQVFK 276 D N R +Q LG R+V+K Sbjct: 268 AGADVV-----NNRMIQDLGDREVYK 288 >4TWL-A nrPDB Length = 246 Score = 66.6 bits (161), Expect = 1e-11, Method: Compositional matrix adjust. Identities = 64/242 (26%), Positives = 98/242 (40%), Gaps = 30/242 (12%) Query: 36 LGPEKWPGACKENQQSPINIVTARTKVNPRLTPFILVGYDQKQQWPIKNNQHTVEMTLGG 95 L PE W K +QSPI + R + L L + ++N+ H V + G Sbjct: 21 LKPE-WETCGKGMEQSPIQLRDNRVIFDQTLGK--LRRNYRAVDARLRNSGHDVLVDFKG 77 Query: 96 GACIIGGDLPARYEAVQLHLHWSNGNDNGSEHSIDGRHFAMEMHIVHKKLTSSKEDSKDK 155 A + + Y+ ++H H + SEH ++G F +E +VH E K Sbjct: 78 NAGSLSINR-VEYQLKRIHFH------SPSEHEMNGERFDLEAQLVH-------ESQDQK 123 Query: 156 FAVLAFMIEVGDKVNKGFQPLVEALPSISKPHSTSTVRESSLQDMLPPSTKM--YTYFRY 213 AV++ + G P + L K S S E + + P ++ Y+RY Sbjct: 124 RAVVSILFRFGRA-----DPFLSDLEDFIKQFSNSQKNEINAGVVDPNQLQIDDSAYYRY 178 Query: 214 NGSLTTPNCDETVIWTVYKQPIKIHKNQFLEFSKNLYYDEDQKLNMKDNVRPLQPLGKRQ 273 GS T P C E + WTV ++ + Q L + + N +N RPLQP R Sbjct: 179 MGSFTAPPCTEGISWTVMRKVATVSPRQVLLLKQAV------NENAINNARPLQPTNFRS 232 Query: 274 VF 275 VF Sbjct: 233 VF 234 >3Q31-A nrPDB Length = 244 Score = 63.2 bits (152), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 63/232 (27%), Positives = 94/232 (40%), Gaps = 42/232 (18%) Query: 37 GPEKWPG------AC-KENQQSPINIVTARTKVNPRLTPFILVGYDQKQQWPIKNNQHTV 89 GP W G AC K QSPI I +A + K P+ + Sbjct: 18 GPLNWYGLDEANEACAKGKHQSPIVIDSAAIDYAASGS--------LKLDLPLADGSKLE 69 Query: 90 EMTLGGGACIIGGDLPAR---YEAVQLHLHWSNGNDNGSEHSIDGRHFAMEMHIVHKKLT 146 + G + G L A Y Q H H SEH ++ HF ME+H V + T Sbjct: 70 NLGFGLQVTLTNGSLTANSKTYTLAQFHFHTP------SEHHVNEEHFPMEVHFVFQ--T 121 Query: 147 SSKEDSKDKFAVLAFMI---EVGDKV---NKGFQPLVEALPSISKPHSTSTVRESSLQDM 200 ++KE AV+ F EVGD V + F P ++ +P +T + L D Sbjct: 122 AAKET-----AVVGFFFQLSEVGDSVPLFDSVFAP-IDNIPDAGTSTTTGQLDFGGLLDH 175 Query: 201 LPPSTKMYTYFRYNGSLTTPNCDETVIWTVYKQPIKIHKNQFLEFSKNLYYD 252 + ++Y GSLTTP C E V+W + +P+ + + + K + Y+ Sbjct: 176 F----NRHGVYQYTGSLTTPPCTEEVMWNLSTEPLPLTVQGYNKVKKIIKYN 223 >5TT3-A nrPDB Length = 234 Score = 62.0 bits (149), Expect = 3e-10, Method: Compositional matrix adjust. Identities = 50/172 (29%), Positives = 71/172 (41%), Gaps = 38/172 (22%) Query: 121 NDNGSEHSIDGRHFAMEM-------------HIVHKKLTSSKEDSKDKFAVLAFMIEVGD 167 N G ++ +D HF M H VHK D+K + VLA E G Sbjct: 85 NYRGHDYVLDNVHFHAPMEFLINNKTRPLSAHFVHK-------DAKGRLLVLAIGFEEG- 136 Query: 168 KVNKGFQPLVEALPSISKPHSTSTVRESSLQDMLPPSTKMYTYFRYNGSLTTPNCDETVI 227 K N P++E + +E +L LP S Y+ +NGSLT P C E V Sbjct: 137 KENPNLDPILEGI------QKKQNFKEVALDAFLPKSI---NYYHFNGSLTAPPCTEGVA 187 Query: 228 WTVYKQPIKIHKNQFLEFSKNLYYDEDQKLNMKDNVRPLQPLGKRQVFKSHA 279 W V ++P+++ Q E K ++ N RP+QP + KS A Sbjct: 188 WFVIEEPLEVSAKQLAEIKK--------RMKNSPNQRPVQPDYNTVIIKSSA 231 >3B1B-A nrPDB Length = 377 Score = 56.6 bits (135), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 43/150 (28%), Positives = 71/150 (47%), Gaps = 19/150 (12%) Query: 103 DLPARYEAV--QLHLHWSNGNDNGSEHSIDGRHFAMEMHIVHKKLTSSKEDSKDKFAVLA 160 D R AV Q H H + SEH + G+ + +E+HIVH+ + F+V Sbjct: 150 DAADRVTAVPTQFHFH------STSEHLLAGKIYPLELHIVHQVTEKLEACKGGCFSVTG 203 Query: 161 FMIEVGDK-VNKGFQPLVEALPS----ISKPHSTSTVRESSLQDMLPPSTKMYTYFRYNG 215 + ++ + N+ +P+ +PS S + +T++ L ++LP Y Y G Sbjct: 204 ILFQLDNGPDNELLEPIFANMPSREGTFSNLPAGTTIK---LGELLPSDRD---YVTYEG 257 Query: 216 SLTTPNCDETVIWTVYKQPIKIHKNQFLEF 245 SLTTP C E ++W V QP +I Q+ + Sbjct: 258 SLTTPPCSEGLLWHVMTQPQRISFGQWNRY 287 >4IZO-A nrPDB Length = 419 Score = 31.2 bits (69), Expect = 0.56, Method: Compositional matrix adjust. Identities = 17/51 (33%), Positives = 25/51 (49%), Gaps = 2/51 (3%) Query: 72 VGYDQKQQWPIKNNQHTVEM--TLGGGACIIGGDLPARYEAVQLHLHWSNG 120 +GYD K Q + Q + +LGG C++ LP +YE L +NG Sbjct: 181 LGYDGKGQVRVATAQEARDAYGSLGGVPCVLEKRLPLKYEVSALIARGANG 231 >5OHK-A nrPDB Length = 336 Score = 30.8 bits (68), Expect = 0.79, Method: Compositional matrix adjust. Identities = 21/66 (31%), Positives = 32/66 (48%), Gaps = 9/66 (13%) Query: 156 FAVLAFMIEVGDKVNKGFQPLVEALPSISKPHSTS---------TVRESSLQDMLPPSTK 206 F ++A ++ GD + F + PS P STS TVR++SLQ++L S Sbjct: 270 FRLMAVVVHHGDMHSGHFVTYRRSPPSARNPLSTSNQWLWVSDDTVRKASLQEVLSSSAY 329 Query: 207 MYTYFR 212 + Y R Sbjct: 330 LLFYER 335 >2VKH-A nrPDB Length = 546 Score = 30.8 bits (68), Expect = 0.80, Method: Compositional matrix adjust. Identities = 26/82 (31%), Positives = 39/82 (47%), Gaps = 11/82 (13%) Query: 121 NDNGSEHSIDGRHFAMEMHIVHKKLTS-SKEDSKDKFAVLAFMIEVGDKVNKGFQPLVEA 179 NDN + +G F M I KL S S ED+ + FMI++ + + GF P V + Sbjct: 411 NDNLNPSINEGTDFNTTMKIFSDKLASISNEDN------MMFMIKITNYLKVGFAPDVRS 464 Query: 180 LPSISKPHSTSTVRESSLQDML 201 ++S P V + QD+L Sbjct: 465 TINLSGP----GVYTGAYQDLL 482 >5OHN-A nrPDB Length = 370 Score = 30.4 bits (67), Expect = 0.87, Method: Compositional matrix adjust. Identities = 21/66 (31%), Positives = 32/66 (48%), Gaps = 9/66 (13%) Query: 156 FAVLAFMIEVGDKVNKGFQPLVEALPSISKPHSTS---------TVRESSLQDMLPPSTK 206 F ++A ++ GD + F + PS P STS TVR++SLQ++L S Sbjct: 304 FRLMAVVVHHGDMHSGHFVTYRRSPPSARNPLSTSNQWLWVSDDTVRKASLQEVLSSSAY 363 Query: 207 MYTYFR 212 + Y R Sbjct: 364 LLFYER 369 >3I2D-A nrPDB Length = 371 Score = 30.4 bits (67), Expect = 1.1, Method: Compositional matrix adjust. Identities = 26/106 (24%), Positives = 48/106 (45%), Gaps = 5/106 (4%) Query: 163 IEVGDKVNKGFQPLV-EALPSISKPHSTSTVRESSLQDMLPPSTKMYTYFRYNGSLTTPN 221 +++ D + +GF+ A P+ PH ++++++ + +TK Y F Y + TP Sbjct: 150 VQIKDNI-RGFKSKPGTAKPADLTPHLKPYTQQNNVELIYAFTTKEYKLFGYIVEMITP- 207 Query: 222 CDETVIWTVYKQPIKIHKNQFLEFSKNLYYDEDQKLNMKDNVRPLQ 267 E ++ V + P I + L K L DE+ L + LQ Sbjct: 208 --EQLLEKVLQHPKIIKQATLLYLKKTLREDEEMGLTTTSTIMSLQ 251 >5JNE-A nrPDB Length = 367 Score = 30.0 bits (66), Expect = 1.2, Method: Compositional matrix adjust. Identities = 23/89 (25%), Positives = 39/89 (43%), Gaps = 3/89 (3%) Query: 179 ALPSISKPHSTSTVRESSLQDMLPPSTKMYTYFRYNGSLTTPNCDETVIWTVYKQPIKIH 238 A P+ PH ++++++ + +TK Y F Y + TP E ++ V + P I Sbjct: 111 AKPADLTPHLKPYTQQNNVELIYAFTTKEYKLFGYIVEMITP---EQLLEKVLQHPKIIK 167 Query: 239 KNQFLEFSKNLYYDEDQKLNMKDNVRPLQ 267 + L K L DE+ L + LQ Sbjct: 168 QATLLYLKKTLREDEEMGLTTTSTIMSLQ 196 >4MKG-A nrPDB Length = 217 Score = 30.0 bits (66), Expect = 1.4, Method: Compositional matrix adjust. Identities = 22/72 (30%), Positives = 33/72 (45%), Gaps = 7/72 (9%) Query: 38 PEKWPGACKEN-----QQSPIN--IVTARTKVNPRLTPFILVGYDQKQQWPIKNNQHTVE 90 P K PG C ++ Q++ N VT R +VN + T +L YD K+ N Q ++ Sbjct: 143 PPKTPGICDKDGGELYQRADDNEETVTKRLEVNMKQTAPLLAFYDSKEVLVNVNGQQDIQ 202 Query: 91 MTLGGGACIIGG 102 I+GG Sbjct: 203 DVFADVKVILGG 214 >4UM8-B nrPDB Length = 788 Score = 29.3 bits (64), Expect = 2.0, Method: Compositional matrix adjust. Identities = 12/40 (30%), Positives = 23/40 (57%) Query: 233 QPIKIHKNQFLEFSKNLYYDEDQKLNMKDNVRPLQPLGKR 272 Q +++H Q ++ +LYY D +M D++ ++ LG R Sbjct: 119 QTLQVHVRQTEDYPVDLYYLMDLSASMDDDLNTIKELGSR 158 >4UM9-D nrPDB Length = 483 Score = 28.9 bits (63), Expect = 2.7, Method: Compositional matrix adjust. Identities = 12/40 (30%), Positives = 23/40 (57%) Query: 233 QPIKIHKNQFLEFSKNLYYDEDQKLNMKDNVRPLQPLGKR 272 Q +++H Q ++ +LYY D +M D++ ++ LG R Sbjct: 102 QTLQVHVRQTEDYPVDLYYLMDLSASMDDDLNTIKELGSR 141 >5FZ5-W nrPDB Length = 482 Score = 28.1 bits (61), Expect = 4.6, Method: Compositional matrix adjust. Identities = 14/54 (25%), Positives = 26/54 (48%), Gaps = 3/54 (5%) Query: 164 EVGDKVNK---GFQPLVEALPSISKPHSTSTVRESSLQDMLPPSTKMYTYFRYN 214 E DK+N+ QP++++L I E +L ++PP + + + YN Sbjct: 167 EKQDKLNRLMDQIQPIIDSLKKIDDSRIEENTFEIALARLIPPQNQSHAAYTYN 220 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 3ZNC-A nrPDB 377 e-105 5JN8-A nrPDB 330 4e-91 1Z93-A nrPDB 301 2e-82 6G4T-A nrPDB 299 9e-82 1FLJ-A nrPDB 298 2e-81 4QK3-A nrPDB 296 7e-81 4CNR-A nrPDB 295 2e-80 6FAF-A nrPDB 290 8e-79 3D0N-A nrPDB 287 4e-78 1URT-A nrPDB 285 2e-77 3FE4-A nrPDB 276 6e-75 4LU3-A nrPDB 272 1e-73 1RJ5-A nrPDB 266 6e-72 5DVX-A nrPDB 262 1e-70 4X5S-A nrPDB 256 7e-69 2W2J-A nrPDB 256 7e-69 5LL9-A nrPDB 256 1e-68 4COQ-A nrPDB 255 1e-68 6EKI-A nrPDB 249 1e-66 4G7A-A nrPDB 244 3e-65 4XZ5-A nrPDB 228 3e-60 4XIW-A nrPDB 219 1e-57 5HPJ-A nrPDB 218 2e-57 4TWL-A nrPDB 212 2e-55 4ETQ-X nrPDB 210 6e-55 6B9J-X nrPDB 208 2e-54 1KOQ-A nrPDB 206 8e-54 1Y7W-A nrPDB 185 2e-47 5TT3-A nrPDB 170 6e-43 3Q31-A nrPDB 162 1e-40 3B1B-A nrPDB 156 2e-38 Sequences not found previously or not previously below threshold: 2YIJ-A nrPDB 31 0.63 4RY2-A nrPDB 29 2.6 2YWO-A nrPDB 29 3.1 5FZ5-W nrPDB 28 5.3 6ID1-L nrPDB 28 5.4 CONVERGED! >3ZNC-A nrPDB Length = 258 Score = 377 bits (967), Expect = e-105, Method: Composition-based stats. Identities = 257/258 (99%), Positives = 258/258 (100%) Query: 22 WCYEIQTKDPRSSCLGPEKWPGACKENQQSPINIVTARTKVNPRLTPFILVGYDQKQQWP 81 WCYEIQT+DPRSSCLGPEKWPGACKENQQSPINIVTARTKVNPRLTPFILVGYDQKQQWP Sbjct: 1 WCYEIQTEDPRSSCLGPEKWPGACKENQQSPINIVTARTKVNPRLTPFILVGYDQKQQWP 60 Query: 82 IKNNQHTVEMTLGGGACIIGGDLPARYEAVQLHLHWSNGNDNGSEHSIDGRHFAMEMHIV 141 IKNNQHTVEMTLGGGACIIGGDLPARYEAVQLHLHWSNGNDNGSEHSIDGRHFAMEMHIV Sbjct: 61 IKNNQHTVEMTLGGGACIIGGDLPARYEAVQLHLHWSNGNDNGSEHSIDGRHFAMEMHIV 120 Query: 142 HKKLTSSKEDSKDKFAVLAFMIEVGDKVNKGFQPLVEALPSISKPHSTSTVRESSLQDML 201 HKKLTSSKEDSKDKFAVLAFMIEVGDKVNKGFQPLVEALPSISKPHSTSTVRESSLQDML Sbjct: 121 HKKLTSSKEDSKDKFAVLAFMIEVGDKVNKGFQPLVEALPSISKPHSTSTVRESSLQDML 180 Query: 202 PPSTKMYTYFRYNGSLTTPNCDETVIWTVYKQPIKIHKNQFLEFSKNLYYDEDQKLNMKD 261 PPSTKMYTYFRYNGSLTTPNCDETVIWTVYKQPIKIHKNQFLEFSKNLYYDEDQKLNMKD Sbjct: 181 PPSTKMYTYFRYNGSLTTPNCDETVIWTVYKQPIKIHKNQFLEFSKNLYYDEDQKLNMKD 240 Query: 262 NVRPLQPLGKRQVFKSHA 279 NVRPLQPLGKRQVFKSHA Sbjct: 241 NVRPLQPLGKRQVFKSHA 258 >5JN8-A nrPDB Length = 266 Score = 330 bits (847), Expect = 4e-91, Method: Composition-based stats. Identities = 147/265 (55%), Positives = 192/265 (72%), Gaps = 6/265 (2%) Query: 19 DSGWCYEIQTKDPRSSCLGPEKWPGACKENQQSPINIVTARTKVNPRLTPFILVGYDQKQ 78 +S WCYE+Q + CL P KW G C++++QSPINIVT + KV+ +L F GYD+KQ Sbjct: 2 ESHWCYEVQAESSNYPCLVPVKWGGNCQKDRQSPINIVTTKAKVDKKLGRFFFSGYDKKQ 61 Query: 79 QWPIKNNQHTVEMTLGGGACIIGGDLPARYEAVQLHLHWSNGNDNGSEHSIDGRHFAMEM 138 W ++NN H+V M L A I GG LPA Y+A QLHLHWS+ GSEHS+DG HFAMEM Sbjct: 62 TWTVQNNGHSVMMLLENKASISGGGLPAPYQAKQLHLHWSDLPYKGSEHSLDGEHFAMEM 121 Query: 139 HIVHKKLTSS------KEDSKDKFAVLAFMIEVGDKVNKGFQPLVEALPSISKPHSTSTV 192 HIVH+K + +D +D+ AVLAF++E G +VN+GFQPLVEAL +I KP ++T+ Sbjct: 122 HIVHEKEKGTSRNVKEAQDPEDEIAVLAFLVEAGTQVNEGFQPLVEALSNIPKPEMSTTM 181 Query: 193 RESSLQDMLPPSTKMYTYFRYNGSLTTPNCDETVIWTVYKQPIKIHKNQFLEFSKNLYYD 252 ESSL D+LP K+ YFRY GSLTTP CDE V+WTV+++PI++H+ Q L FS+ LYYD Sbjct: 182 AESSLLDLLPKEEKLRHYFRYLGSLTTPTCDEKVVWTVFREPIQLHREQILAFSQKLYYD 241 Query: 253 EDQKLNMKDNVRPLQPLGKRQVFKS 277 ++Q ++MKDNVRPLQ LG+R V KS Sbjct: 242 KEQTVSMKDNVRPLQQLGQRTVIKS 266 >1Z93-A nrPDB Length = 266 Score = 301 bits (771), Expect = 2e-82, Method: Composition-based stats. Identities = 77/266 (28%), Positives = 117/266 (43%), Gaps = 18/266 (6%) Query: 21 GWCYEIQTKDPRSSCLGPEKWPGACKENQQSPINIVTARTKVNPRLTPFILVGYDQKQQW 80 W Y L P K QSPI + T + +P L P+ V YD Sbjct: 4 EWGYASHNGPDHWHELFP-----NAKGENQSPIELHTKDIRHDPSLQPW-SVSYDGGSAK 57 Query: 81 PIKNNQHTVEMTLGGG---ACIIGGDLPARYEAVQLHLHWSNGNDNGSEHSIDGRHFAME 137 I NN T + + + GG LP Y Q HLHW + +D+GSEH++DG +A E Sbjct: 58 TILNNGKTCRVVFDDTYDRSMLRGGPLPGPYRLRQFHLHWGSSDDHGSEHTVDGVKYAAE 117 Query: 138 MHIVHK----KLTSSKEDSKDKFAVLAFMIEVGDKVNKGFQPLVEALPSISKPHSTSTVR 193 +H+VH +D AV+ +++G N FQ ++AL I + Sbjct: 118 LHLVHWNPKYNTFKEALKQRDGIAVIGIFLKIG-HENGEFQIFLDALDKIKTKGKEAPFT 176 Query: 194 ESSLQDMLPPSTKMYTYFRYNGSLTTPNCDETVIWTVYKQPIKIHKNQFLEFSKNLYYDE 253 + + P S Y+ Y GS TTP C+E ++W + K+P+ + +Q + L E Sbjct: 177 KFDPSSLFPASRD---YWTYQGSFTTPPCEECIVWLLLKEPMTVSSDQMAKLRSLLSSAE 233 Query: 254 DQ-KLNMKDNVRPLQPLGKRQVFKSH 278 ++ + + N RP QP+ R V S Sbjct: 234 NEPPVPLVSNWRPPQPINNRVVRASF 259 >6G4T-A nrPDB Length = 274 Score = 299 bits (766), Expect = 9e-82, Method: Composition-based stats. Identities = 84/271 (30%), Positives = 126/271 (46%), Gaps = 19/271 (7%) Query: 17 TEDSGWCYEIQTKDPRSSCLGPEKWPGACKENQQSPINIVTARTKVNPRLTPFILVGYDQ 76 T GW Y L P + ++QSPINI++++ +P L P L Y+ Sbjct: 4 TGHHGWGYGQDDGPSHWHKLYP-----IAQGDRQSPINIISSQAVYSPSLQPLEL-SYEA 57 Query: 77 KQQWPIKNNQHTVEMTL---GGGACIIGGDLPARYEAVQLHLHWSNGNDNGSEHSIDGRH 133 I NN H+V++ + GG L Y Q H HW +D GSEH++DG+ Sbjct: 58 CMSLSITNNGHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKS 117 Query: 134 FAMEMHIVHKKLTSS-----KEDSKDKFAVLAFMIEVGDKVNKGFQPLVEALPSISKPHS 188 F E+H+VH + D AV+ +E GD + L +AL + + Sbjct: 118 FPSELHLVHWNAKKYSTFGEAASAPDGLAVVGVFLETGD-EHPSMNRLTDALYMVRFKGT 176 Query: 189 TSTVRESSLQDMLPPSTKMYTYFRYNGSLTTPNCDETVIWTVYKQPIKIHKNQFLEFSKN 248 + + + +LP S Y+ Y GSLTTP E+V W V ++PI I + Q +F Sbjct: 177 KAQFSCFNPKSLLPASR---HYWTYPGSLTTPPLSESVTWIVLREPISISERQMGKFRSL 233 Query: 249 LYYDE-DQKLNMKDNVRPLQPLGKRQVFKSH 278 L+ E D++++M +N RP QPL R V S Sbjct: 234 LFTSEDDERIHMVNNFRPPQPLKGRVVKASF 264 >1FLJ-A nrPDB Length = 260 Score = 298 bits (764), Expect = 2e-81, Method: Composition-based stats. Identities = 74/266 (27%), Positives = 115/266 (43%), Gaps = 18/266 (6%) Query: 21 GWCYEIQTKDPRSSCLGPEKWPGACKENQQSPINIVTARTKVNPRLTPFILVGYDQKQQW 80 W Y L P K + QSPI + T + +P L P+ V YD Sbjct: 4 EWGYASHNGPEHWHELYP-----IAKGDNQSPIELHTKDIRHDPSLQPW-SVSYDPGSAK 57 Query: 81 PIKNNQHTVEMTLGGG---ACIIGGDLPARYEAVQLHLHWSNGNDNGSEHSIDGRHFAME 137 I NN T + + + GG L Y Q HLHW + +D+GSEH++DG +A E Sbjct: 58 TILNNGKTCRVVFDDTFDRSMLRGGPLSGPYRLRQFHLHWGSSDDHGSEHTVDGVKYAAE 117 Query: 138 MHIVHK----KLTSSKEDSKDKFAVLAFMIEVGDKVNKGFQPLVEALPSISKPHSTSTVR 193 +H+VH D AV+ +++G + FQ L++AL I + Sbjct: 118 LHLVHWNPKYNTFGEALKQPDGIAVVGIFLKIGREK-GEFQILLDALDKIKTKGKEAPFN 176 Query: 194 ESSLQDMLPPSTKMYTYFRYNGSLTTPNCDETVIWTVYKQPIKIHKNQFLEFSKNLYYDE 253 + P Y+ Y+GS TTP C+E ++W + K+P+ + +Q + E Sbjct: 177 HFDPSCLFPACRD---YWTYHGSFTTPPCEECIVWLLLKEPMTVSSDQMAKLRSLFASAE 233 Query: 254 DQ-KLNMKDNVRPLQPLGKRQVFKSH 278 ++ + + N RP QP+ R V S Sbjct: 234 NEPPVPLVGNWRPPQPIKGRVVRASF 259 >4QK3-A nrPDB Length = 249 Score = 296 bits (758), Expect = 7e-81, Method: Composition-based stats. Identities = 85/265 (32%), Positives = 113/265 (42%), Gaps = 27/265 (10%) Query: 21 GWCYEIQTKDPRSSCLGPEKWPGACKENQQSPINIVTARTKVNPRLTPFILVGYDQKQQW 80 W Y P K +QSP++I T K +P L P V YDQ Sbjct: 4 HWGYGKHNGPEHWHKDFP-----IAKGERQSPVDIDTHTAKYDPSLKPL-SVSYDQATSL 57 Query: 81 PIKNNQHTVEMTLGG---GACIIGGDLPARYEAVQLHLHWSNGNDNGSEHSIDGRHFAME 137 I NN H + A + GG L Y +Q H HW + + GSEH++D + +A E Sbjct: 58 RILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAE 117 Query: 138 MHIVHKKLT----SSKEDSKDKFAVLAFMIEVGDKVNKGFQPLVEALPSISKPHSTSTVR 193 +H+VH D AVL ++VG G Q +V+ L SI ++ Sbjct: 118 LHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAK-PGLQKVVDVLDSIKTKGKSADFT 176 Query: 194 ESSLQDMLPPSTKMYTYFRYNGSLTTPNCDETVIWTVYKQPIKIHKNQFLEFSKNLYYDE 253 + +LP S Y+ Y GSLTTP E V W V K+PI + Q L+F K Sbjct: 177 NFDPRGLLPESLD---YWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKL----- 228 Query: 254 DQKLNMKDNVRPLQPLGKRQVFKSH 278 M DN RP QPL RQ+ S Sbjct: 229 -----MVDNWRPAQPLKNRQIKASF 248 >4CNR-A nrPDB Length = 262 Score = 295 bits (754), Expect = 2e-80, Method: Composition-based stats. Identities = 78/263 (29%), Positives = 115/263 (43%), Gaps = 18/263 (6%) Query: 21 GWCYEIQTKDPRSSCLGPEKWPGACKENQQSPINIVTARTKVNPRLTPFILVGYDQKQQW 80 W Y+ P +QSP++I T +P L P L Y + Sbjct: 6 HWGYDKHNGPEHWHKDFP-----IANGERQSPVDIDTDAVVQDPALKPLAL-DYGEATSR 59 Query: 81 PIKNNQHTVEMTLGG---GACIIGGDLPARYEAVQLHLHWSNGNDNGSEHSIDGRHFAME 137 + N+ H+ + A + G L Y VQ H HW + +D GSEH++D + +A E Sbjct: 60 RMVNDGHSFNVEYDDSQDKAVLKDGPLTGTYRLVQFHFHWGSSDDQGSEHTVDRKKYAAE 119 Query: 138 MHIVHKKLT----SSKEDSKDKFAVLAFMIEVGDKVNKGFQPLVEALPSISKPHSTSTVR 193 +H+VH + D AV+ ++VGD N Q +++AL SI ++ Sbjct: 120 LHLVHWNTKYGDFGTAAQEPDGLAVVGVFLKVGDA-NPALQKVLDALDSIKTKGKSTDFP 178 Query: 194 ESSLQDMLPPSTKMYTYFRYNGSLTTPNCDETVIWTVYKQPIKIHKNQFLEFSKNLYYDE 253 +LP + Y+ Y GSLTTP E+V W V K+PI + Q L+F + E Sbjct: 179 NFDPGSLLP---NVLDYWTYPGSLTTPPLLESVTWIVLKEPISVSSQQMLKFRTLNFNAE 235 Query: 254 DQKLN-MKDNVRPLQPLGKRQVF 275 + M N RP QPL RQV Sbjct: 236 GEPEELMLANWRPAQPLKNRQVR 258 >6FAF-A nrPDB Length = 261 Score = 290 bits (741), Expect = 8e-79, Method: Composition-based stats. Identities = 77/267 (28%), Positives = 118/267 (44%), Gaps = 19/267 (7%) Query: 21 GWCYEIQTKDPRSSCLGPEKWPGACKENQQSPINIVTARTKVNPRLTPFILVGYDQKQQW 80 W Y+ + + S L P N QSP++I T+ TK + L P I V Y+ Sbjct: 5 DWGYDDKNGPEQWSKLYP-----IANGNNQSPVDIKTSETKHDTSLKP-ISVSYNPATAK 58 Query: 81 PIKNNQHTVEMTLGGG---ACIIGGDLPARYEAVQLHLHWSNGNDNGSEHSIDGRHFAME 137 I N H+ + + + GG Y Q H HW + N++GSEH++DG ++ E Sbjct: 59 EIINVGHSFHVNFEDNDNRSVLKGGPFSDSYRLFQFHFHWGSTNEHGSEHTVDGVKYSAE 118 Query: 138 MHIVHKKLTSS-----KEDSKDKFAVLAFMIEVGDKVNKGFQPLVEALPSISKPHSTSTV 192 +H+ H D AV+ +++VG+ N Q +++AL +I + Sbjct: 119 LHVAHWNSAKYSSLAEAASKADGLAVIGVLMKVGEA-NPKLQKVLDALQAIKTKGKRAPF 177 Query: 193 RESSLQDMLPPSTKMYTYFRYNGSLTTPNCDETVIWTVYKQPIKIHKNQFLEFSKNLYYD 252 +LP S ++ Y GSLT P E+V W + K+ I + Q +F L Sbjct: 178 TNFDPSTLLPSSLD---FWTYPGSLTHPPLYESVTWIICKESISVSSEQLAQFRSLLSNV 234 Query: 253 E-DQKLNMKDNVRPLQPLGKRQVFKSH 278 E D + M+ N RP QPL R V S Sbjct: 235 EGDNAVPMQHNNRPTQPLKGRTVRASF 261 >3D0N-A nrPDB Length = 264 Score = 287 bits (735), Expect = 4e-78, Method: Composition-based stats. Identities = 83/266 (31%), Positives = 115/266 (43%), Gaps = 19/266 (7%) Query: 22 WCYEIQTKDPRSSCLGPEKWPGACKENQQSPINIVTARTKVNPRLTPFILVGYDQKQQWP 81 W Y P +QQSPI I T K + L P + YD Sbjct: 8 WGYREHNGPIHWKEFFP-----IADGDQQSPIEIKTKEVKYDSSLRPL-SIKYDPSSAKI 61 Query: 82 IKNNQHTVEMTLGG---GACIIGGDLPARYEAVQLHLHWSNGNDNGSEHSIDGRHFAMEM 138 I N+ H+ + + + GG L Y Q+HLHW + +D+GSEH +DG +A E+ Sbjct: 62 ISNSGHSFNVDFDDTENKSVLRGGPLTGSYRLRQVHLHWGSADDHGSEHIVDGVSYAAEL 121 Query: 139 HIVHKKLTSS-----KEDSKDKFAVLAFMIEVGDKVNKGFQPLVEALPSISKPHSTSTVR 193 H+VH D AVL +++G+ N Q + + L SI + + Sbjct: 122 HVVHWNSDKYPSFVEAAHEPDGLAVLGVFLQIGEP-NSQLQKITDTLDSIKEKGKQTRFT 180 Query: 194 ESSLQDMLPPSTKMYTYFRYNGSLTTPNCDETVIWTVYKQPIKIHKNQFLEFSKNLYYDE 253 L +LPPS + Y+ Y GSLT P E+V W V KQPI I Q +F L E Sbjct: 181 NFDLLSLLPPS---WDYWTYPGSLTVPPLLESVTWIVLKQPINISSQQLAKFRSLLCTAE 237 Query: 254 DQKLN-MKDNVRPLQPLGKRQVFKSH 278 + + N RP QPL R+V S Sbjct: 238 GEAAAFLVSNHRPPQPLKGRKVRASF 263 >1URT-A nrPDB Length = 248 Score = 285 bits (729), Expect = 2e-77, Method: Composition-based stats. Identities = 71/244 (29%), Positives = 115/244 (47%), Gaps = 14/244 (5%) Query: 44 ACKENQQSPINIVTARTKVNPRLTPFILVGYDQKQQWPIKNNQHTVEMTLGGG---ACII 100 + + +QSPINI + +P+L P V YD + N H ++ + I Sbjct: 1 SAEGTRQSPINIQWKDSVYDPQLAPL-RVSYDAASCRYLWNTGHAFQVEFDDSCEDSGIS 59 Query: 101 GGDLPARYEAVQLHLHWSNGNDNGSEHSIDGRHFAMEMHIVHKKLTSSKEDSK-----DK 155 GG L Y Q H HW ++ GSEH++DG + E+H+VH T + K + Sbjct: 60 GGPLGNHYRLKQFHFHWGATDEWGSEHAVDGHTYPAELHLVHWNSTKYENYKKASVGENG 119 Query: 156 FAVLAFMIEVGDKVNKGFQPLVEALPSISKPHSTSTVRESSLQDMLPPSTKMYTYFRYNG 215 AV+ +++G ++ Q LV+ LP + + + + ++P Y+ Y G Sbjct: 120 LAVIGVFLKLGAH-HQALQKLVDVLPEVRHKDTQVAMGDFDPSCLMPACRD---YWTYPG 175 Query: 216 SLTTPNCDETVIWTVYKQPIKIHKNQFLEFSKNLYYDEDQKL-NMKDNVRPLQPLGKRQV 274 SLTTP E+V W V K P+++ +Q F L+ ++ M +N RPLQPL R++ Sbjct: 176 SLTTPPLAESVTWIVQKTPVEVSPSQLSMFRTLLFSGRGEEEDVMVNNYRPLQPLRDRKL 235 Query: 275 FKSH 278 S Sbjct: 236 RSSF 239 >3FE4-A nrPDB Length = 278 Score = 276 bits (707), Expect = 6e-75, Method: Composition-based stats. Identities = 89/275 (32%), Positives = 138/275 (50%), Gaps = 18/275 (6%) Query: 20 SGWCYEIQTKDPRSSCLGPEKWPGACKENQQSPINIVTARTKVNPRLTPFILVGYD-QKQ 78 S W Y D P+ +P AC +QSPIN+ + + NP L + GY+ Q Sbjct: 2 SDWTYSEGALDE---AHWPQHYP-ACGGQRQSPINLQRTKVRYNPSLKGLNMTGYETQAG 57 Query: 79 QWPIKNNQHTVEMTLGGGACIIGGDLPARYEAVQLHLHWSNGND--NGSEHSIDGRHFAM 136 ++P+ NN HTV+++L + D Y A Q+H HW + +GSEH++DG + Sbjct: 58 EFPMVNNGHTVQISLPSTMRMTVADGTV-YIAQQMHFHWGGASSEISGSEHTVDGIRHVI 116 Query: 137 EMHIVHK----KLTSSKEDSKDKFAVLAFMIEVGDK-VNKGFQPLVEALPSISKPHSTST 191 E+HIVH K +D+ D AVLA +EV + N + + L +I P +T Sbjct: 117 EIHIVHYNSKYKSYDIAQDAPDGLAVLAAFVEVKNYPENTYYSNFISHLANIKYPGQRTT 176 Query: 192 VRESSLQDMLPPSTKMYTYFRYNGSLTTPNCDETVIWTVYKQPIKIHKNQFLEFSKNLYY 251 + +QDMLP + + Y+ Y+GSLTTP C E V W V +K+ + Q + +L Sbjct: 177 LTGLDVQDMLPRNLQH--YYTYHGSLTTPPCTENVHWFVLADFVKLSRTQVWKLENSLL- 233 Query: 252 DEDQKLNMKDNVRPLQPLGKRQVFKSHAPGQLLSL 286 + + + ++ R QPL R V +S+ P Q +L Sbjct: 234 -DHRNKTIHNDYRRTQPLNHRVV-ESNFPNQEYTL 266 >4LU3-A nrPDB Length = 279 Score = 272 bits (696), Expect = 1e-73, Method: Composition-based stats. Identities = 96/284 (33%), Positives = 138/284 (48%), Gaps = 21/284 (7%) Query: 21 GWCYEIQTKDPRSSCLGPEKWPGACKENQQSPINIVTARTKVNPRLTPFILVGYDQKQQW 80 W YE PE C N QSPI+I T +P L GYDQ Sbjct: 6 HWTYEGPHGQDHWPASYPE-----CGNNAQSPIDIQTDSVTFDPDLPALQPHGYDQPGTE 60 Query: 81 PI--KNNQHTVEMTLGGGACIIGGDLPARYEAVQLHLHWS-NGNDNGSEHSIDGRHFAME 137 P+ NN HTV+++L + + G LP +Y A QLHLHW G+ GSEH I+ E Sbjct: 61 PLDLHNNGHTVQLSLP--STLYLGGLPRKYVAAQLHLHWGQKGSPGGSEHQINSEATFAE 118 Query: 138 MHIVHKKLTSS-----KEDSKDKFAVLAFMIEVGDKVNKGFQPLVEALPSISKPHSTSTV 192 +HIVH S + AVL +IEVG+ N ++ ++ L + ++V Sbjct: 119 LHIVHYDSDSYDSLSEAAERPQGLAVLGILIEVGETKNIAYEHILSHLHEVRHKDQKTSV 178 Query: 193 RESSLQDMLPPSTKMYTYFRYNGSLTTPNCDETVIWTVYKQPIKIHKNQFLEFSKNLYYD 252 +L+++LP ++ YFRYNGSLTTP C ++V+WTV+ + +I Q + L+ Sbjct: 179 PPFNLRELLP--KQLGQYFRYNGSLTTPPCYQSVLWTVFYRRSQISMEQLEKLQGTLFST 236 Query: 253 EDQKLN-MKDNVRPLQPLGKRQVFKSHA-PGQLLSLPLPTLLVP 294 E++ + N R LQPL +R VF S G + +LVP Sbjct: 237 EEEPSKLLVQNYRALQPLNQRMVFASFIQAGSSYT--TGEMLVP 278 >1RJ5-A nrPDB Length = 261 Score = 266 bits (681), Expect = 6e-72, Method: Composition-based stats. Identities = 90/267 (33%), Positives = 128/267 (47%), Gaps = 18/267 (6%) Query: 21 GWCYEIQTKDPRSSCLGPEKWPGACKENQQSPINIVTARTKVNPRLTPFILVGYDQKQQW 80 W YE PE C + QSPINI T +P L GYDQ Sbjct: 4 HWTYEGPHGQDHWPTSYPE-----CGGDAQSPINIQTDSVIFDPDLPAVQPHGYDQLGTE 58 Query: 81 PI--KNNQHTVEMTLGGGACIIGGDLPARYEAVQLHLHWSN-GNDNGSEHSIDGRHFAME 137 P+ NN HTV+++L + G LP +Y A QLHLHW G+ GSEH I+ A E Sbjct: 59 PLDLHNNGHTVQLSLPP--TLHLGGLPRKYTAAQLHLHWGQRGSLEGSEHHINSEATAAE 116 Query: 138 MHIVHKKLTSS-----KEDSKDKFAVLAFMIEVGDKVNKGFQPLVEALPSISKPHSTSTV 192 +H+VH S AVL +IEVG+ N + ++ L I ++V Sbjct: 117 LHVVHYDSQSYSSLSEAAQKPQGLAVLGILIEVGETENPAYDHILSRLHEIRYKDQKTSV 176 Query: 193 RESSLQDMLPPSTKMYTYFRYNGSLTTPNCDETVIWTVYKQPIKIHKNQFLEFSKNLYY- 251 S++++ P ++ +FRYNGSLTTP C ++V+WTV+ + +I Q + + L Sbjct: 177 PPFSVRELFP--QQLEQFFRYNGSLTTPPCYQSVLWTVFNRRAQISMGQLEKLQETLSST 234 Query: 252 DEDQKLNMKDNVRPLQPLGKRQVFKSH 278 +ED + N R QPL +R +F S Sbjct: 235 EEDPSEPLVQNYRVPQPLNQRTIFASF 261 >5DVX-A nrPDB Length = 260 Score = 262 bits (669), Expect = 1e-70, Method: Composition-based stats. Identities = 86/267 (32%), Positives = 125/267 (46%), Gaps = 19/267 (7%) Query: 21 GWCYEIQTKDPRSSCLGPEKWPGACKENQQSPINIVTARTKVNPRLTPFILVGYDQKQ-- 78 W Y DP + P AC QSP++I +P L P L G+ Sbjct: 1 HWRY---GGDPPWPRVSP-----ACAGRFQSPVDIRPQLAAFSPALRPLELSGFQLPPLP 52 Query: 79 QWPIKNNQHTVEMTLGGGACIIGGDLPARYEAVQLHLHWSNGNDNGSEHSIDGRHFAMEM 138 + ++NN H+V++TL G + G Y A+QLHLHW GSEH+++G F E+ Sbjct: 53 ELRLRNNGHSVQLTLPPGLEMKLGP-GREYRALQLHLHWGAAGRPGSEHTVEGHRFPAEI 111 Query: 139 HIVHKKLTSSKEDS----KDKFAVLAFMIEVGDKVNKGFQPLVEALPSISKPHSTSTVRE 194 H+VH ++ D AVLA +E G + N ++ L+ L I++ S + V Sbjct: 112 HVVHLSTKYARVDEALGRPGGLAVLAAFLEEGPEENSAYEQLLSRLEEIAEEGSETQVPG 171 Query: 195 SSLQDMLPPSTKMYTYFRYNGSLTTPNCDETVIWTVYKQPIKIHKNQFLEFSKNLYYDED 254 + +LP YF+Y GSLTTP C + VIWTV+ Q + + Q S L+ D Sbjct: 172 LDISALLPS--DFSRYFQYEGSLTTPPCAQGVIWTVFNQTVSLSAKQLHTLSDTLWGPGD 229 Query: 255 QKLNMKDNVRPLQPLGKRQVFKSHAPG 281 +L + N R QPL R + S G Sbjct: 230 SRLQL--NFRATQPLNGRVIEASFPAG 254 >4X5S-A nrPDB Length = 232 Score = 256 bits (655), Expect = 7e-69, Method: Composition-based stats. Identities = 75/262 (28%), Positives = 116/262 (44%), Gaps = 36/262 (13%) Query: 18 EDSGWCYEIQTKDPRSSCLGPEKWPGACKENQQSPINIVTARTKVNPRLTPFILVGYDQK 77 E W YE + + L PE + C QSP++I + KV+ +L + Y++ Sbjct: 6 EVHHWSYEGENGPENWAKLNPEYF--WCNLKNQSPVDI-SDNYKVHAKLEKLH-INYNKA 61 Query: 78 QQWPIKNNQHTVEMT-LGGGACIIGGDLPARYEAVQLHLHWSNGNDNGSEHSIDGRHFAM 136 I NN HT+++ L I G Y Q H H SEH+++G+++ + Sbjct: 62 VNPEIVNNGHTIQVNVLEDFKLNIKGK---EYHLKQFHFHAP------SEHTVNGKYYPL 112 Query: 137 EMHIVHKKLTSSKEDSKDKFAVLAFMIEVGDKVNKGFQPLVEALPSISKPHSTSTVRESS 196 EMH+VHK D AV+ + G K N + + ++ + S + Sbjct: 113 EMHLVHK-------DKDGNIAVIGVFFKEG-KANPELDKVFKN--ALKEEGSKVFDGSIN 162 Query: 197 LQDMLPPSTKMYTYFRYNGSLTTPNCDETVIWTVYKQPIKIHKNQFLEFSKNLYYDEDQK 256 + +LPP Y+ Y+GSLTTP C E V+W V KQPI K Q F + Sbjct: 163 INALLPPVKN---YYTYSGSLTTPPCTEGVLWIVLKQPITASKQQIELFKSIMK------ 213 Query: 257 LNMKDNVRPLQPLGKRQVFKSH 278 +N RP QP+ R + +S+ Sbjct: 214 ---HNNNRPTQPINSRYILESN 232 >2W2J-A nrPDB Length = 291 Score = 256 bits (655), Expect = 7e-69, Method: Composition-based stats. Identities = 67/248 (27%), Positives = 115/248 (46%), Gaps = 16/248 (6%) Query: 45 CKENQQSPINIVTARTKVNPRLTPFILV-GYDQKQQWPIKNNQHTVEMTLGGGACIIGGD 103 QSPIN+ + + +P L L Y + + N+ HT+++ L + + GG Sbjct: 45 ANGEYQSPINLNSREARYDPSLLDVRLSPNYVVCRDCEVTNDGHTIQVILKSKSVLSGGP 104 Query: 104 LPA--RYEAVQLHLHWSNGNDNGSEHSIDGRHFAMEMHIVHKKLTSSKE-----DSKDKF 156 LP +E ++ HW N GSEH+++ + F ME+H++H T Sbjct: 105 LPQGHEFELYEVRFHWGRENQRGSEHTVNFKAFPMELHLIHWNSTLFGSIDEAVGKPHGI 164 Query: 157 AVLAFMIEVGDKVNKGFQPLVEALPSISKPHSTSTVRESSLQDMLPPSTKMYTYFRYNGS 216 A++A +++G K + G + + E L I + T+ + +LP + Y+ Y GS Sbjct: 165 AIIALFVQIG-KEHVGLKAVTEILQDIQYKGKSKTIPCFNPNTLLP-DPLLRDYWVYEGS 222 Query: 217 LTTPNCDETVIWTVYKQPIKIHKNQFLEFSKNLYYDEDQKLN------MKDNVRPLQPLG 270 LT P C E V W +++ P+ I + Q EF + + + +L + DN RP QPL Sbjct: 223 LTIPPCSEGVTWILFRYPLTISQLQIEEFRRLRTHVKGAELVEGCDGILGDNFRPTQPLS 282 Query: 271 KRQVFKSH 278 R + + Sbjct: 283 DRVIRAAF 290 >5LL9-A nrPDB Length = 263 Score = 256 bits (653), Expect = 1e-68, Method: Composition-based stats. Identities = 92/271 (33%), Positives = 140/271 (51%), Gaps = 21/271 (7%) Query: 20 SGWCYEIQTKDPRSSCLGPEKWPGACKENQQSPINIVTARTKVNPRLTPFILVGYD--QK 77 S W Y + S P +C QSPI++ + + + LTP GY+ Sbjct: 2 SKWTYFGPDGENSWSKKYP-----SCGGLLQSPIDLHSDILQYDASLTPLEFQGYNLSAN 56 Query: 78 QQWPIKNNQHTVEMTLGGGACIIGGDLPARYEAVQLHLHWSNGND-NGSEHSIDGRHFAM 136 +Q+ + NN H+V++ L I G L +RY A QLHLHW N ND +GSEH++ G+HFA Sbjct: 57 KQFLLTNNGHSVKLNLPSDMHIQG--LQSRYSATQLHLHWGNPNDPHGSEHTVSGQHFAA 114 Query: 137 EMHIVHKKLT-----SSKEDSKDKFAVLAFMIEVGDKVNKGFQPLVEALPSISKPHSTST 191 E+HIVH S+ + + AVLA +IE+G N + + L + + Sbjct: 115 ELHIVHYNSDLYPDASTASNKSEGLAVLAVLIEMG-SFNPSYDKIFSHLQHVKYKGQEAF 173 Query: 192 VRESSLQDMLPPSTKMYTYFRYNGSLTTPNCDETVIWTVYKQPIKIHKNQFLEFSKNLY- 250 V +++++LP T Y+RY GSLTTP C+ TV+WTV++ P++I + Q L LY Sbjct: 174 VPGFNIEELLPERT--AEYYRYRGSLTTPPCNPTVLWTVFRNPVQISQEQLLALETALYC 231 Query: 251 --YDEDQKLNMKDNVRPLQPLGKRQVFKSHA 279 D+ M +N R +Q +R V+ S + Sbjct: 232 THMDDPSPREMINNFRQVQKFDERLVYTSFS 262 >4COQ-A nrPDB Length = 247 Score = 255 bits (652), Expect = 1e-68, Method: Composition-based stats. Identities = 75/257 (29%), Positives = 111/257 (43%), Gaps = 35/257 (13%) Query: 21 GWCYEIQTKDPRSSCLGPEKWPGACK-ENQQSPINIVTARTKVNPRLTPFILVGYDQKQQ 79 W Y L PE CK QSPI+I +A V L P + Y Sbjct: 25 HWGYSGSIGPEHWGDLSPEY--LMCKIGKNQSPIDINSADA-VKACLAPVSV--YYVSDA 79 Query: 80 WPIKNNQHTVEMTLGGGACIIGGDLPARYEAVQLHLHWSNGNDNGSEHSIDGRHFAMEMH 139 + NN HT+++ +GG ++ R+ Q H H SEH+++G+H+ E H Sbjct: 80 KYVVNNGHTIKVVMGGRGYVVVDG--KRFYLKQFHFHAP------SEHTVNGKHYPFEAH 131 Query: 140 IVHKKLTSSKEDSKDKFAVLAFMIEVGDKVNKGFQPLVEALPSISKPHSTSTVRESSLQD 199 VH D VL +VG K N + + +P + Sbjct: 132 FVHL-------DKNGNITVLGVFFKVG-KENPELEKVWRVMPEEP-GQKRHLTARIDPEK 182 Query: 200 MLPPSTKMYTYFRYNGSLTTPNCDETVIWTVYKQPIKIHKNQFLEFSKNLYYDEDQKLNM 259 +LP + Y+RY+GSLTTP C E V W V+K+P+++ + Q +F K + + Sbjct: 183 LLPENRD---YYRYSGSLTTPPCSEGVRWIVFKEPVEMSREQLEKFRKVMGF-------- 231 Query: 260 KDNVRPLQPLGKRQVFK 276 DN RP+QPL R+V K Sbjct: 232 -DNNRPVQPLNARKVMK 247 >6EKI-A nrPDB Length = 226 Score = 249 bits (635), Expect = 1e-66, Method: Composition-based stats. Identities = 76/257 (29%), Positives = 110/257 (42%), Gaps = 38/257 (14%) Query: 21 GWCYEIQTKDPRSSCLGPEKWPGACK-ENQQSPINIVTARTKVNPRLTPFILVGYDQKQQ 79 W Y +T L E CK QSP++I V L I + Y Sbjct: 5 HWSYHGETGPQHWGDLKNEY--IMCKIGKNQSPVDISR---IVEAELEK-IKINYSSGGS 58 Query: 80 WPIKNNQHTVEMTLGGGACIIGGDLPARYEAVQLHLHWSNGNDNGSEHSIDGRHFAMEMH 139 I NN HT++++ G+ II + R+E Q H H SEH+I G+ + E H Sbjct: 59 -SITNNGHTIKVSYEPGSYIIVDGI--RFELKQFHFHAP------SEHTIKGKSYPFEAH 109 Query: 140 IVHKKLTSSKEDSKDKFAVLAFMIEVGDKVNKGFQPLVEALPSISKPHSTSTVRESSLQD 199 VH D AV+ + + G K N + + E LP K + + + D Sbjct: 110 FVHA-------DKDGNLAVIGVIFKEG-KKNPIIEKIWENLPEAGK--TIKLAHKINAYD 159 Query: 200 MLPPSTKMYTYFRYNGSLTTPNCDETVIWTVYKQPIKIHKNQFLEFSKNLYYDEDQKLNM 259 +LP K Y+RY+GSLTTP C E V W V ++ +++ K Q +F K Sbjct: 160 LLPKKKK---YYRYSGSLTTPPCSEGVRWIVMEEEMELSKEQIEKFRKL---------MG 207 Query: 260 KDNVRPLQPLGKRQVFK 276 D RP+QPL R + + Sbjct: 208 GDTNRPVQPLNARMIME 224 >4G7A-A nrPDB Length = 248 Score = 244 bits (623), Expect = 3e-65, Method: Composition-based stats. Identities = 71/260 (27%), Positives = 115/260 (44%), Gaps = 34/260 (13%) Query: 19 DSGWCYEIQTKDPRSSCLGPEKWPGACKENQQSPINIVTARTKVNPRLTPFILVGYDQKQ 78 + W YE + + L PE + CK QSPINI + KV L P + + Y + Sbjct: 23 EHEWSYEGEKGPEHWAQLKPEFF--WCKLKNQSPINID-KKYKVKANL-PKLNLYYKTAK 78 Query: 79 QWPIKNNQHTVEMTLGGGACIIGGDLPARYEAVQLHLHWSNGNDNGSEHSIDGRHFAMEM 138 + + NN HT+++ + + L +Y+ Q H H SEH+I+ + + +E+ Sbjct: 79 ESEVVNNGHTIQINIKEDNTL--NYLGEKYQLKQFHFH------TPSEHTIEKKSYPLEI 130 Query: 139 HIVHKKLTSSKEDSKDKFAVLAFMIEVGDKVNKGFQPLVEALPSISKPHSTSTVRESSLQ 198 H VHK K V+ M ++G K NK ++ P+ + + +L Sbjct: 131 HFVHKT-------EDGKILVVGVMAKLG-KTNKELDKILNVAPA--EEGEKILDKNLNLN 180 Query: 199 DMLPPSTKMYTYFRYNGSLTTPNCDETVIWTVYKQPIKIHKNQFLEFSKNLYYDEDQKLN 258 +++P Y Y+GSLTTP C E V W V K+PI I K Q + + Sbjct: 181 NLIPKDK---RYMTYSGSLTTPPCTEGVRWIVLKKPISISKQQLEKLKS---------VM 228 Query: 259 MKDNVRPLQPLGKRQVFKSH 278 + N RP+Q + R + + Sbjct: 229 VNPNNRPVQEINSRWIIEGF 248 >4XZ5-A nrPDB Length = 233 Score = 228 bits (580), Expect = 3e-60, Method: Composition-based stats. Identities = 73/259 (28%), Positives = 106/259 (40%), Gaps = 32/259 (12%) Query: 21 GWCYEIQTKDPRSSCLGPEKWPGACKENQQSPINIVTARTKVNPRLTPFILVGYDQKQQW 80 W Y + L PE + QSPIN+ L F + Y ++ Sbjct: 3 HWGYFGEEGPQYWGELAPE-FSTCKTGKNQSPINLKPQTAVGTTSLPGFDV--YYRETAL 59 Query: 81 PIKNNQHTVEMTLGGGACIIGGDLPARYEAVQLHLHWSNGNDNGSEHSIDGRHFAMEMHI 140 + NN HT+++ + G+ I RYE +Q H H SEH DG ++ MEMH+ Sbjct: 60 KLINNGHTLQVNIPLGSYIKING--HRYELLQYHFH------TPSEHQRDGFNYPMEMHL 111 Query: 141 VHKKLTSSKEDSKDKFAVLAFMIEVGDKVNKGFQPLVEALPSISKPHSTSTVRESSLQDM 200 VHK D AV+A + + G+ N+ L+ LP K + Sbjct: 112 VHK-------DGDGNLAVIAILFQEGE-ENETLAKLMSFLPQTLKKQEIHESVKIHPAKF 163 Query: 201 LPPSTKMYTYFRYNGSLTTPNCDETVIWTVYKQPIKIHKNQFLEFSKNLYYDEDQKLNMK 260 P K +++Y+GSLTTP C E V W V+KQPI+ Q + + Sbjct: 164 FPADKK---FYKYSGSLTTPPCSEGVYWMVFKQPIQASVTQLEK----------MHEYLG 210 Query: 261 DNVRPLQPLGKRQVFKSHA 279 N RP+Q R + KS Sbjct: 211 SNARPVQRQNARTLLKSWP 229 >4XIW-A nrPDB Length = 239 Score = 219 bits (558), Expect = 1e-57, Method: Composition-based stats. Identities = 80/245 (32%), Positives = 111/245 (45%), Gaps = 27/245 (11%) Query: 37 GPEKWPGACK-ENQQSPINI--VTARTKVNPRLTPFILVGYDQKQQWPIKNNQH-TVEMT 92 GP W G C +QSPINI T+ KV+ + F Y ++ + N H T+++ Sbjct: 11 GPPTWKGVCATGKRQSPINIPLNTSAPKVDAEMGEFDFA-YGSFEKCDVLNTGHGTMQVN 69 Query: 93 LGGGACIIGGDLPARYEAVQLHLHWSNGNDNGSEHSIDGRHFAMEMHIVHKKLTSSKEDS 152 G G++ E +Q H H SEH++DGR +AME H+VHK S Sbjct: 70 FPAGNLAFIGNM--ELELLQFHFHAP------SEHAMDGRRYAMEAHLVHKNK------S 115 Query: 153 KDKFAVLAFMIEVGDK-VNKGFQPLVEALPSISKPHSTSTVRESSLQDMLPPSTKMYT-- 209 AVL M+E G N +E P + S + + +LP +K T Sbjct: 116 TGNLAVLGIMLEPGGLIKNPALSTALEVAPEVPLAKKPSP-KGINPVMLLPKKSKAGTRP 174 Query: 210 YFRYNGSLTTPNCDETVIWTVYKQPIKIHKNQFLEFSKNLYYDEDQKLNMKDNVRPLQPL 269 + Y GSLTTP C E V W V+ QPIK+ +Q L+F + + N RPLQ L Sbjct: 175 FVHYPGSLTTPPCSEGVDWFVFMQPIKVPDSQILDFMRFV----GDNKTYATNTRPLQLL 230 Query: 270 GKRQV 274 R V Sbjct: 231 NSRLV 235 >5HPJ-A nrPDB Length = 217 Score = 218 bits (556), Expect = 2e-57, Method: Composition-based stats. Identities = 68/257 (26%), Positives = 105/257 (40%), Gaps = 41/257 (15%) Query: 21 GWCYEIQTKDPRSSCLGPEKWPGACKENQQSPINIVTARTKVNPRLTPFILVGYDQKQQW 80 W Y + + + + Q+PI+I L P L Q + Sbjct: 1 EWSYTGEHGTEHWG----DSFATCAEGVNQTPIDINQT---TQAELAPLHLDYEGQVTE- 52 Query: 81 PIKNNQHTVEMTLGGGACIIGGDLPARYEAVQLHLHWSNGNDNGSEHSIDGRHFAMEMHI 140 + NN HT++ L G + +E Q H H SE+ + G+ + +E H Sbjct: 53 -LVNNGHTIQANLTGKNTLTVDG--KTFELKQFHFH------TPSENYLKGKQYPLEAHF 103 Query: 141 VHKKLTSSKEDSKDKFAVLAFMIEVGDKVNKGFQPLVEALPSISKPHSTSTVRE-SSLQD 199 VH K + AV+A M + G + N L+ ++PS T ++E + D Sbjct: 104 VHAT-------DKGELAVVAVMFDFGPRSNNELTTLLASIPS---KGQTVELKEALNPAD 153 Query: 200 MLPPSTKMYTYFRYNGSLTTPNCDETVIWTVYKQPIKIHKNQFLEFSKNLYYDEDQKLNM 259 +LP + Y+R+NGSLTTP C E V W V ++P K Q + M Sbjct: 154 LLPRDRE---YYRFNGSLTTPPCSEGVRWFVMQEPQTSSKAQTEKLQ----------AVM 200 Query: 260 KDNVRPLQPLGKRQVFK 276 +N RPLQPL R + + Sbjct: 201 GNNARPLQPLNARLILE 217 >4TWL-A nrPDB Length = 246 Score = 212 bits (539), Expect = 2e-55, Method: Composition-based stats. Identities = 63/250 (25%), Positives = 97/250 (38%), Gaps = 30/250 (12%) Query: 28 TKDPRSSCLGPEKWPGACKENQQSPINIVTARTKVNPRLTPFILVGYDQKQQWPIKNNQH 87 L PE W K +QSPI + R + L + ++N+ H Sbjct: 13 NGPENWGNLKPE-WETCGKGMEQSPIQLRDNRVIFDQTLGKL--RRNYRAVDARLRNSGH 69 Query: 88 TVEMTLGGGACIIGGDLPARYEAVQLHLHWSNGNDNGSEHSIDGRHFAMEMHIVHKKLTS 147 V + G A + + Y+ ++H H + SEH ++G F +E +VH Sbjct: 70 DVLVDFKGNAGSLSINR-VEYQLKRIHFH------SPSEHEMNGERFDLEAQLVH----- 117 Query: 148 SKEDSKDKFAVLAFMIEVGDKVNKGFQPLVEALPSISKPHSTSTVRESSLQDMLPPSTKM 207 E K AV++ + G P + L K S S E + + P ++ Sbjct: 118 --ESQDQKRAVVSILFRFGRA-----DPFLSDLEDFIKQFSNSQKNEINAGVVDPNQLQI 170 Query: 208 YT--YFRYNGSLTTPNCDETVIWTVYKQPIKIHKNQFLEFSKNLYYDEDQKLNMKDNVRP 265 Y+RY GS T P C E + WTV ++ + Q L + + N +N RP Sbjct: 171 DDSAYYRYMGSFTAPPCTEGISWTVMRKVATVSPRQVLLLKQAV------NENAINNARP 224 Query: 266 LQPLGKRQVF 275 LQP R VF Sbjct: 225 LQPTNFRSVF 234 >4ETQ-X nrPDB Length = 269 Score = 210 bits (534), Expect = 6e-55, Method: Composition-based stats. Identities = 73/231 (31%), Positives = 108/231 (46%), Gaps = 13/231 (5%) Query: 48 NQQSPINIVTARTKVNPRLTPFILVGYDQKQQWPIKNNQHTVEMTLGGGACIIGGDLPAR 107 Q SPINI T + N RL P + Y++ + I+N V + GG I GG LP Sbjct: 3 QQLSPINIETKKAISNARLKPL-DIHYNESKPTTIQNTGKLVRINFKGG-YISGGFLPNE 60 Query: 108 YEAVQLHLHWSNGNDNGSEHSIDGRHFAMEMHIVHK--KLTSSKEDSK---DKFAVLAFM 162 Y LH++W +D GS H ID ++ E+++VH K SS E++K D +++ Sbjct: 61 YVLSSLHIYWGKEDDYGSNHLIDVYKYSGEINLVHWNKKKYSSYEEAKKHDDGLIIISIF 120 Query: 163 IEVGDKVNKGFQPLVEALPSISKPHSTSTVRESSLQDMLPPSTKMYTYFRYNGSLTTPNC 222 ++V D N FQ +V L SI ++++ D L PS YF Y G TT N Sbjct: 121 LQVLDHKNVYFQKIVNQLDSIRSANTSAPFDSVFYLDNLLPSK--LDYFTYLG--TTINH 176 Query: 223 DETVIWTVYKQPIKIHKNQFLEFSKNLYYD--EDQKLNMKDNVRPLQPLGK 271 +W ++ PI IH +Q +F L E + + +N R L Sbjct: 177 SADAVWIIFPTPINIHSDQLSKFRTLLSLSNHEGKPHYITENYRNPYKLND 227 >6B9J-X nrPDB Length = 241 Score = 208 bits (530), Expect = 2e-54, Method: Composition-based stats. Identities = 73/231 (31%), Positives = 108/231 (46%), Gaps = 13/231 (5%) Query: 48 NQQSPINIVTARTKVNPRLTPFILVGYDQKQQWPIKNNQHTVEMTLGGGACIIGGDLPAR 107 Q SPINI T + N RL P + Y++ + I+N V + GG I GG LP Sbjct: 3 QQLSPINIETKKAISNARLKPL-DIHYNESKPTTIQNTGKLVRINFKGG-YISGGFLPNE 60 Query: 108 YEAVQLHLHWSNGNDNGSEHSIDGRHFAMEMHIVHK--KLTSSKEDSK---DKFAVLAFM 162 Y LH++W +D GS H ID ++ E+++VH K SS E++K D +++ Sbjct: 61 YVLSSLHIYWGKEDDYGSNHLIDVYKYSGEINLVHWNKKKYSSYEEAKKHDDGLIIISIF 120 Query: 163 IEVGDKVNKGFQPLVEALPSISKPHSTSTVRESSLQDMLPPSTKMYTYFRYNGSLTTPNC 222 ++V D N FQ +V L SI ++++ D L PS YF Y G TT N Sbjct: 121 LQVLDHKNVYFQKIVNQLDSIRSANTSAPFDSVFYLDNLLPSK--LDYFTYLG--TTINH 176 Query: 223 DETVIWTVYKQPIKIHKNQFLEFSKNLYYD--EDQKLNMKDNVRPLQPLGK 271 +W ++ PI IH +Q +F L E + + +N R L Sbjct: 177 SADAVWIIFPTPINIHSDQLSKFRTLLSLSNHEGKPHYITENYRNPYKLND 227 >1KOQ-A nrPDB Length = 223 Score = 206 bits (525), Expect = 8e-54, Method: Composition-based stats. Identities = 73/258 (28%), Positives = 103/258 (39%), Gaps = 37/258 (14%) Query: 20 SGWCYEIQTKDPRSSCLGPEKWPGACKENQQSPINIVTARTKVNPRLTPFILVGYDQKQQ 79 + W Y L E++ QSP+NI V+ +L P I V Y + Sbjct: 2 THWGYTGHDSPESWGNLS-EEFRLCSTGKNQSPVNITET---VSGKL-PAIKVNY-KPSM 55 Query: 80 WPIKNNQHTVEMTLG-GGACIIGGDLPARYEAVQLHLHWSNGNDNGSEHSIDGRHFAMEM 138 ++NN HT+++ GG + Y Q H H SE+ I GR F ME Sbjct: 56 VDVENNGHTIQVNYPEGGNTLTVNGRT--YTLKQFHFHVP------SENQIKGRTFPMEA 107 Query: 139 HIVHKKLTSSKEDSKDKFAVLAFMIEVGDKVNKGFQPLVEALPSISKPHSTSTVRESSLQ 198 H VH D + VLA + E G K N + +P + Sbjct: 108 HFVHL-------DENKQPLVLAVLYEAG-KTNGRLSSIWNVMPM--TAGKVKLNQPFDAS 157 Query: 199 DMLPPSTKMYTYFRYNGSLTTPNCDETVIWTVYKQPIKIHKNQFLEFSKNLYYDEDQKLN 258 +LP K Y+R+ GSLTTP C E V W V K I + Q +F++ + + Sbjct: 158 TLLPKRLK---YYRFAGSLTTPPCTEGVSWLVLKTYDHIDQAQAEKFTRAVGSE------ 208 Query: 259 MKDNVRPLQPLGKRQVFK 276 N RP+QPL R V + Sbjct: 209 ---NNRPVQPLNARVVIE 223 >1Y7W-A nrPDB Length = 291 Score = 185 bits (470), Expect = 2e-47, Method: Composition-based stats. Identities = 69/262 (26%), Positives = 108/262 (41%), Gaps = 34/262 (12%) Query: 37 GPEKWPGACKENQQSPINIVTAR-----TKVNPRLTPFILVGYDQKQQWPIKNNQHTVEM 91 G K+P AC + QSPI+I T + ++ + D Q I V++ Sbjct: 39 GTTKYP-ACSGSNQSPIDINTNQLMEPSSRSGTSAVSLNGLNVDGAQADGITLTNAKVDL 97 Query: 92 TLGGGAC----------IIGGDLPARYEAVQLHLHWSNGNDNGSEHSIDGRHFAMEMHIV 141 G I G + +Q H H SEH+I+G H+ +E+HIV Sbjct: 98 EQGMKVTFDQPAANLPTIEIGGTTKSFVPIQFHFHHFL-----SEHTINGIHYPLELHIV 152 Query: 142 HKKLTSSKEDSKDKFAVLAFMI---EVGDKVNKGFQPLVEA-LPSISKPHSTSTVRESSL 197 ++ + + + AV+ M E GD Q +E + + + + V ++ Sbjct: 153 MQE-QDPADVATAQLAVIGIMYKYSENGDAFLNSLQTQIEGKIGDGTASYGDTGVSIDNI 211 Query: 198 Q---DMLPPSTKMYTYFRYNGSLTTPNCDETVIWTVYKQPIKIHKNQFLEFSKNLYYDED 254 +LP S K Y Y+GSLTTP CDE V W V+ P ++ + Q F Sbjct: 212 NVKTQLLPSSLK---YAGYDGSLTTPGCDERVKWHVFTTPREVTREQMKLFVDVTMGAHA 268 Query: 255 QKLNMKDNVRPLQPLGKRQVFK 276 + N R +Q LG R+V+K Sbjct: 269 GADVV--NNRMIQDLGDREVYK 288 >5TT3-A nrPDB Length = 234 Score = 170 bits (431), Expect = 6e-43, Method: Composition-based stats. Identities = 63/262 (24%), Positives = 99/262 (37%), Gaps = 38/262 (14%) Query: 19 DSGWCYEI-QTKDPRSSCLGPEKWPGACKENQQSPINIVTARTKVNPRLTPFILVGYDQK 77 ++ W Y+ + R L + + QSPINI + + + Y Sbjct: 7 NTKWDYKNKENGPHRWDKLHKD-FEVCKSGKSQSPINI---EHYYHTQDKADLQFKYAAS 62 Query: 78 QQWPIKNNQHTVEMTLGGGACIIGGDLPARYEAVQLHLHWSNGNDNGSEHSIDGRHFAME 137 + + HT++ + I Y +H H E I+ + + Sbjct: 63 KPKAVFFTHHTLKASFEPTNHI--NYRGHDYVLDNVHFHAPM------EFLINNKTRPLS 114 Query: 138 MHIVHKKLTSSKEDSKDKFAVLAFMIEVGDKVNKGFQPLVEALPSISKPHSTSTVRESSL 197 H VHK D+K + VLA E G K N P++E + +E +L Sbjct: 115 AHFVHK-------DAKGRLLVLAIGFEEG-KENPNLDPILEGIQ------KKQNFKEVAL 160 Query: 198 QDMLPPSTKMYTYFRYNGSLTTPNCDETVIWTVYKQPIKIHKNQFLEFSKNLYYDEDQKL 257 LP S Y+ +NGSLT P C E V W V ++P+++ Q E K ++ Sbjct: 161 DAFLPKSIN---YYHFNGSLTAPPCTEGVAWFVIEEPLEVSAKQLAEIKK--------RM 209 Query: 258 NMKDNVRPLQPLGKRQVFKSHA 279 N RP+QP + KS A Sbjct: 210 KNSPNQRPVQPDYNTVIIKSSA 231 >3Q31-A nrPDB Length = 244 Score = 162 bits (411), Expect = 1e-40, Method: Composition-based stats. Identities = 59/244 (24%), Positives = 91/244 (37%), Gaps = 46/244 (18%) Query: 37 GPEKWPG-------ACKENQQSPINIVTARTKVNPRLTPFILVGYDQKQQWPIKNNQHTV 89 GP W G K QSPI I +A + K P+ + Sbjct: 18 GPLNWYGLDEANEACAKGKHQSPIVIDSAAIDYAASGS--------LKLDLPLADGSKLE 69 Query: 90 EMTLGGGACIIGGDLPAR---YEAVQLHLHWSNGNDNGSEHSIDGRHFAMEMHIVHKKLT 146 + G + G L A Y Q H H SEH ++ HF ME+H V + Sbjct: 70 NLGFGLQVTLTNGSLTANSKTYTLAQFHFH------TPSEHHVNEEHFPMEVHFVFQT-- 121 Query: 147 SSKEDSKDKFAVLAFMI---EVGDKVNKGFQPLVEALPSISKPHSTSTVRESSLQDMLPP 203 + + AV+ F EVGD V F + + +I +++T + +L Sbjct: 122 -----AAKETAVVGFFFQLSEVGDSV-PLFDSVFAPIDNIPDAGTSTTTGQLDFGGLL-D 174 Query: 204 STKMYTYFRYNGSLTTPNCDETVIWTVYKQPIKIHKNQFLEFSKNLYYDEDQKLNMKDNV 263 + ++Y GSLTTP C E V+W + +P+ + + + K + Y N Sbjct: 175 HFNRHGVYQYTGSLTTPPCTEEVMWNLSTEPLPLTVQGYNKVKKIIKY----------NA 224 Query: 264 RPLQ 267 R Q Sbjct: 225 RYTQ 228 >3B1B-A nrPDB Length = 377 Score = 156 bits (393), Expect = 2e-38, Method: Composition-based stats. Identities = 65/272 (23%), Positives = 101/272 (37%), Gaps = 58/272 (21%) Query: 28 TKDPRSSCLGPEKWPG--------ACK-ENQQSPIN------IVTARTKVNPRLT----- 67 + D L E W G CK +QSPIN + +K+ L Sbjct: 36 SGDHWDHGLNGENWEGKDGAGNAWVCKTGRKQSPINVPQYQVLDGKGSKIANGLQTQWSY 95 Query: 68 PFILVGYDQKQQWPIKNNQHTVEM----TLGGGACIIG------------------GDLP 105 P ++ + NN HT+++ G A I D Sbjct: 96 PDLMSN---GTSVQVINNGHTIQVQWTYNYAGHATIAIPAMHNQTNRIVDVLEMRPNDAA 152 Query: 106 ARYEAV--QLHLHWSNGNDNGSEHSIDGRHFAMEMHIVHKKLTSSKEDSKDKFAVLAFMI 163 R AV Q H H + SEH + G+ + +E+HIVH+ + F+V + Sbjct: 153 DRVTAVPTQFHFH------STSEHLLAGKIYPLELHIVHQVTEKLEACKGGCFSVTGILF 206 Query: 164 EVGDK-VNKGFQPLVEALPSISKPHSTSTV-RESSLQDMLPPSTKMYTYFRYNGSLTTPN 221 ++ + N+ +P+ +PS S L ++LP Y Y GSLTTP Sbjct: 207 QLDNGPDNELLEPIFANMPSREGTFSNLPAGTTIKLGELLPSDRD---YVTYEGSLTTPP 263 Query: 222 CDETVIWTVYKQPIKIHKNQFLEFSKNLYYDE 253 C E ++W V QP +I Q+ + + E Sbjct: 264 CSEGLLWHVMTQPQRISFGQWNRYRLAVGLKE 295 >2YIJ-A nrPDB Length = 419 Score = 31.2 bits (69), Expect = 0.63, Method: Composition-based stats. Identities = 20/95 (21%), Positives = 31/95 (32%), Gaps = 9/95 (9%) Query: 140 IVHKKLTSSKEDSKDKFAVLAFMIEVGDKVNKGFQPLVEALPSISKPHSTS--------- 190 IV K V AF+ + F+ L L I + + Sbjct: 249 IVANGYNRPKSRPDKSCPVTAFVFASPRVGDSDFRKLFSGLEDIRVLRTRNLPDVIPIYP 308 Query: 191 TVRESSLQDMLPPSTKMYTYFRYNGSLTTPNCDET 225 + S + D P T+ Y + G+L T +C E Sbjct: 309 PIGYSEVGDEFPIDTRKSPYMKSPGNLATFHCLEG 343 >4RY2-A nrPDB Length = 730 Score = 28.9 bits (63), Expect = 2.6, Method: Composition-based stats. Identities = 16/51 (31%), Positives = 23/51 (45%), Gaps = 4/51 (7%) Query: 236 KIHKNQFLEFSKNLYYDEDQKLNMKDNVRPLQPLGKRQVFKSHAPGQLLSL 286 + Q L F+ L Y N+ D LQPL + V S+ G++L L Sbjct: 422 NMSGGQLLAFNALLAYFLTPVKNLID----LQPLIQTAVVASNRLGEILEL 468 >2YWO-A nrPDB Length = 188 Score = 28.9 bits (63), Expect = 3.1, Method: Composition-based stats. Identities = 29/194 (14%), Positives = 51/194 (26%), Gaps = 40/194 (20%) Query: 92 TLGGGACIIGGDLP----ARYEAVQLH-------L---HWSNGNDNGSEHSIDGRHFAME 137 L + +I +LP RY Q H H + E + + Sbjct: 6 ELPLESPLIDAELPDPRGGRYRLSQFHEPLLAVVFMCNHCPYVKGSIGELVALAERYRGK 65 Query: 138 MHIVHKKLTSSKEDSKDKFAVLAFMIEVGDKVNKGFQPLVEALPSISKPHSTSTVRESSL 197 + V ++ +D +A E ++ ++K + E L Sbjct: 66 VAFVGINANDYEKYPEDAPEKMAAFAEEHGIFFPYL---LDETQEVAKAYRALRTPEVFL 122 Query: 198 QDMLPPSTKMYTYFRYNGSLTTPNCDETVIWTVYKQPIKIHKNQFLEFSKNLYYDEDQKL 257 D RY+G + K P K+ + + L E+ L Sbjct: 123 FD-------ERRLLRYHGRVNDNP----------KDPSKVQSHDLEAAIEALLRGEEPPL 165 Query: 258 NMKD------NVRP 265 RP Sbjct: 166 KEAPAIGCTIKWRP 179 >5FZ5-W nrPDB Length = 482 Score = 28.1 bits (61), Expect = 5.3, Method: Composition-based stats. Identities = 10/42 (23%), Positives = 20/42 (47%) Query: 173 FQPLVEALPSISKPHSTSTVRESSLQDMLPPSTKMYTYFRYN 214 QP++++L I E +L ++PP + + + YN Sbjct: 179 IQPIIDSLKKIDDSRIEENTFEIALARLIPPQNQSHAAYTYN 220 >6ID1-L nrPDB Length = 802 Score = 28.1 bits (61), Expect = 5.4, Method: Composition-based stats. Identities = 8/34 (23%), Positives = 15/34 (44%) Query: 12 YVAPSTEDSGWCYEIQTKDPRSSCLGPEKWPGAC 45 ++ PS + + W E + K + L P +W Sbjct: 53 WLDPSIKKTEWSREEEEKLLHLAKLMPTQWRTIA 86 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.311 0.130 0.404 Lambda K H 0.267 0.0400 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 12,251,128 Number of Sequences: 36641 Number of extensions: 482731 Number of successful extensions: 1412 Number of sequences better than 10.0: 39 Number of HSP's better than 10.0 without gapping: 66 Number of HSP's successfully gapped in prelim test: 18 Number of HSP's that attempted gapping in prelim test: 1088 Number of HSP's gapped (non-prelim): 87 length of query: 305 length of database: 10,336,785 effective HSP length: 97 effective length of query: 208 effective length of database: 6,782,608 effective search space: 1410782464 effective search space used: 1410782464 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 59 (27.4 bits)