BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q63739 (173 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 5LXQ-B nrPDB 366 e-102 1XM2-A nrPDB 362 e-101 3RZ2-A nrPDB 356 3e-99 1ZCK-A nrPDB 322 5e-89 5K23-A nrPDB 319 3e-88 5K22-A nrPDB 312 5e-86 1V3A-A nrPDB 296 3e-81 3S4O-A nrPDB 141 2e-34 1OHC-A nrPDB 59 1e-09 5XW4-A nrPDB 52 1e-07 5Z59-A nrPDB 51 2e-07 3RO1-A nrPDB 46 9e-06 5BZX-A nrPDB 44 3e-05 4BPC-A nrPDB 44 4e-05 1LAR-A nrPDB 42 2e-04 5HDE-A nrPDB 41 3e-04 3M4U-A nrPDB 41 3e-04 2H03-A nrPDB 38 0.002 3I36-A nrPDB 37 0.005 2I75-A nrPDB 37 0.006 4ERC-A nrPDB 36 0.010 6D3F-A nrPDB 36 0.011 2JJD-A nrPDB 35 0.014 2QEP-A nrPDB 35 0.017 2C46-A nrPDB 35 0.018 2R0B-A nrPDB 35 0.019 3V0J-A nrPDB 34 0.031 4YR8-G nrPDB 34 0.032 2I1Y-A nrPDB 34 0.040 1WRM-A nrPDB 34 0.040 4AZ1-A nrPDB 33 0.047 1WCH-A nrPDB 33 0.072 2GJT-A nrPDB 33 0.075 3LJ8-A nrPDB 33 0.077 4JMK-A nrPDB 33 0.087 1I9T-A nrPDB 32 0.11 2CFV-A nrPDB 32 0.12 4H1O-A nrPDB 32 0.15 4PVG-A nrPDB 32 0.16 5OVR-A nrPDB 32 0.17 2B3O-A nrPDB 32 0.17 6H8S-A nrPDB 32 0.18 3F41-A nrPDB 32 0.18 6CMQ-A nrPDB 32 0.20 2PI7-A nrPDB 32 0.20 2BZL-A nrPDB 31 0.21 4GE6-A nrPDB 31 0.21 1P15-A nrPDB 31 0.22 6DR7-A nrPDB 31 0.23 1YN9-A nrPDB 31 0.35 4BJO-A nrPDB 30 0.48 3S3F-A nrPDB 30 0.55 1ZZW-A nrPDB 30 0.55 2OUD-A nrPDB 30 0.60 2C7S-A nrPDB 30 0.74 1RPM-A nrPDB 30 0.79 4Y2E-A nrPDB 29 1.0 6D4D-A nrPDB 29 1.1 2Y96-A nrPDB 29 1.1 2A8B-A nrPDB 29 1.1 3OLR-A nrPDB 29 1.1 1YFO-A nrPDB 28 1.7 2OOQ-A nrPDB 28 2.1 5AWX-A nrPDB 28 2.1 5XJV-A nrPDB 28 2.4 1UPI-A nrPDB 28 2.6 1PM7-A nrPDB 28 2.7 3EZZ-A nrPDB 27 3.3 3RGQ-A nrPDB 27 3.4 4KYQ-A nrPDB 27 3.8 5CG0-A nrPDB 27 4.3 2CU0-A nrPDB 27 4.4 4PDK-A nrPDB 27 5.4 2NV5-A nrPDB 27 5.7 6BZS-A nrPDB 26 7.0 6D67-A nrPDB 26 9.6 >5LXQ-B nrPDB Length = 196 Score = 366 bits (940), Expect = e-102, Method: Compositional matrix adjust. Identities = 173/173 (100%), Positives = 173/173 (100%) Query: 1 MARMNRPAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEK 60 MARMNRPAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEK Sbjct: 24 MARMNRPAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEK 83 Query: 61 EGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALI 120 EGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALI Sbjct: 84 EGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALI 143 Query: 121 EGGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFKDSNGHRNNCCIQ 173 EGGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFKDSNGHRNNCCIQ Sbjct: 144 EGGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFKDSNGHRNNCCIQ 196 >1XM2-A nrPDB Length = 173 Score = 362 bits (929), Expect = e-101, Method: Compositional matrix adjust. Identities = 172/173 (99%), Positives = 172/173 (99%) Query: 1 MARMNRPAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEK 60 MARMNRPAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEK Sbjct: 1 MARMNRPAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEK 60 Query: 61 EGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALI 120 EGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVH VAGLGRAPVLVALALI Sbjct: 61 EGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHSVAGLGRAPVLVALALI 120 Query: 121 EGGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFKDSNGHRNNCCIQ 173 EGGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFKDSNGHRNNCCIQ Sbjct: 121 EGGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFKDSNGHRNNCCIQ 173 >3RZ2-A nrPDB Length = 189 Score = 356 bits (913), Expect = 3e-99, Method: Compositional matrix adjust. Identities = 169/169 (100%), Positives = 169/169 (100%) Query: 1 MARMNRPAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEK 60 MARMNRPAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEK Sbjct: 21 MARMNRPAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEK 80 Query: 61 EGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALI 120 EGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALI Sbjct: 81 EGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALI 140 Query: 121 EGGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFKDSNGHRNN 169 EGGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFKDSNGHRNN Sbjct: 141 EGGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFKDSNGHRNN 189 >1ZCK-A nrPDB Length = 154 Score = 322 bits (825), Expect = 5e-89, Method: Compositional matrix adjust. Identities = 154/154 (100%), Positives = 154/154 (100%) Query: 7 PAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEKEGIHVL 66 PAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEKEGIHVL Sbjct: 1 PAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEKEGIHVL 60 Query: 67 DWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALIEGGMKY 126 DWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALIEGGMKY Sbjct: 61 DWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALIEGGMKY 120 Query: 127 EDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRF 160 EDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRF Sbjct: 121 EDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRF 154 >5K23-A nrPDB Length = 189 Score = 319 bits (818), Expect = 3e-88, Method: Compositional matrix adjust. Identities = 149/170 (87%), Positives = 160/170 (94%), Gaps = 3/170 (1%) Query: 4 MNRPAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEKEGI 63 MNRPAPVE++Y+NMRFLITHNPTNATLNKF EELKKYGVTT+VRVC+ATYD VEKEGI Sbjct: 23 MNRPAPVEISYENMRFLITHNPTNATLNKFTEELKKYGVTTLVRVCDATYDKAPVEKEGI 82 Query: 64 HVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALIEGG 123 HVLDWPFDDGAPP NQIVDDWL+L+K KFREEPGCC+AVHCVAGLGRAPVLVALALIE G Sbjct: 83 HVLDWPFDDGAPPPNQIVDDWLNLLKTKFREEPGCCVAVHCVAGLGRAPVLVALALIECG 142 Query: 124 MKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFKDSNGHRNNCCIQ 173 MKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRF+D+NGH CC+Q Sbjct: 143 MKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFRDTNGH---CCVQ 189 >5K22-A nrPDB Length = 183 Score = 312 bits (799), Expect = 5e-86, Method: Compositional matrix adjust. Identities = 144/165 (87%), Positives = 155/165 (93%) Query: 2 ARMNRPAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEKE 61 + MNRPAPVE++Y+NMRFLITHNPTNATLNKF EELKKYGVTT+VRVC+ATYD VEKE Sbjct: 19 SHMNRPAPVEISYENMRFLITHNPTNATLNKFTEELKKYGVTTLVRVCDATYDKAPVEKE 78 Query: 62 GIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALIE 121 GIHVLDWPFDDGAPP NQIVDDWL+L+K KFREEPG +AVHCVAGLGRAPVLVALALIE Sbjct: 79 GIHVLDWPFDDGAPPPNQIVDDWLNLLKTKFREEPGAAVAVHCVAGLGRAPVLVALALIE 138 Query: 122 GGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFKDSNGH 166 GMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRF+D+NGH Sbjct: 139 AGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFRDTNGH 183 >1V3A-A nrPDB Length = 173 Score = 296 bits (759), Expect = 3e-81, Method: Compositional matrix adjust. Identities = 136/172 (79%), Positives = 152/172 (88%) Query: 1 MARMNRPAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEK 60 MARMNRPAPVEV+YK+MRFLITHNPTNATL+ FIE+LKKYG TT+VRVCE TYD T +EK Sbjct: 1 MARMNRPAPVEVSYKHMRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEK 60 Query: 61 EGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALI 120 +GI V+DWPFDDGAPP ++V+DWLSLVK KF E PG C+AVHCVAGLGRAPVLVALALI Sbjct: 61 DGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALI 120 Query: 121 EGGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFKDSNGHRNNCCI 172 E GMKYEDA+QFIRQKRRGA NSKQL YLEKYRPK RLRFKD + H+ CC+ Sbjct: 121 ESGMKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQRLRFKDPHTHKTRCCV 172 >3S4O-A nrPDB Length = 167 Score = 141 bits (355), Expect = 2e-34, Method: Compositional matrix adjust. Identities = 70/144 (48%), Positives = 94/144 (65%), Gaps = 7/144 (4%) Query: 17 MRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEKEGIHVLDWPFDDGAPP 76 FLI P+ + L +I+EL+ GV +VRVC TYD TLV+ GI V WPFDDGAPP Sbjct: 23 FHFLILDAPSPSNLPTYIKELQHRGVRHLVRVCGPTYDATLVKSRGIDVHSWPFDDGAPP 82 Query: 77 SNQIVDDWLSLVKIKF---REEPGC---CIAVHCVAGLGRAPVLVALALIE-GGMKYEDA 129 + ++D WL L+ + +E+P I VHCVAGLGRAP+LVALAL+E G + DA Sbjct: 83 TRAVLDSWLKLLDTELARQQEDPSVPPPTIGVHCVAGLGRAPILVALALVEYGNVSALDA 142 Query: 130 VQFIRQKRRGAFNSKQLLYLEKYR 153 + IR+KR+GA N Q+ ++ KY+ Sbjct: 143 IALIREKRKGAINQTQMHWITKYK 166 >1OHC-A nrPDB Length = 348 Score = 58.9 bits (141), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 37/118 (31%), Positives = 59/118 (50%), Gaps = 6/118 (5%) Query: 33 FIEELKKYGVTTIVRVCEATYDTTLVEKEGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKF 92 +I+ K + VTTI+R+ + YD G D F DG+ P++ IV ++L + Sbjct: 210 YIQYFKNHNVTTIIRLNKRMYDAKRFTDAGFDHHDLFFADGSTPTDAIVKEFLDIC---- 265 Query: 93 REEPGCCIAVHCVAGLGRAPVLVALALIEG-GMKYEDAVQFIRQKRRGAFNSKQLLYL 149 E IAVHC AGLGR L+A +++ M + + ++R R G+ Q +L Sbjct: 266 -ENAEGAIAVHCKAGLGRTGTLIACYIMKHYRMTAAETIAWVRICRPGSVIGPQQQFL 322 >5XW4-A nrPDB Length = 415 Score = 52.0 bits (123), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 41/134 (30%), Positives = 58/134 (43%), Gaps = 7/134 (5%) Query: 25 PTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEKEGIHVLDWPFDDGAPPSNQIVDDW 84 P + LN F V +VR+ Y+ E GI LD F+DG P IV ++ Sbjct: 251 PFKSVLNFFANN----NVQLVVRLNSHLYNKKHFEDIGIQHLDLIFEDGTCPDLSIVKNF 306 Query: 85 LSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALIEG-GMKYEDAVQFIRQKRRGAFNS 143 + + + G IAVHC AGLGR L+ LI G + + F+R R G Sbjct: 307 VGAAETIIKR--GGKIAVHCKAGLGRTGCLIGAHLIYTYGFTANECIGFLRFIRPGMVVG 364 Query: 144 KQLLYLEKYRPKMR 157 Q +L ++ R Sbjct: 365 PQQHWLYLHQNDFR 378 >5Z59-A nrPDB Length = 147 Score = 51.2 bits (121), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 36/133 (27%), Positives = 63/133 (47%), Gaps = 5/133 (3%) Query: 14 YKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEKEGIHVLDWPFDDG 73 + + R + P L++ + V +V E Y EK G+ VL P D Sbjct: 7 FIDGRVAFSRMPAERELDEVARDFD--AVVVLVEDYELPYSLDEWEKRGVEVLHGPIPDF 64 Query: 74 APPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRA-PVLVALALIEGGMKYEDAVQF 132 PS + + + L ++ + RE G + +HC+ GLGR+ V VA + G+ +A+ Sbjct: 65 TAPSVEQLLEILRWIEERVRE--GKKVLIHCMGGLGRSGTVGVAWLMYSRGLSLREALME 122 Query: 133 IRQKRRGAFNSKQ 145 +R+KR GA +++ Sbjct: 123 VRRKRPGAVETQE 135 >3RO1-A nrPDB Length = 161 Score = 45.8 bits (107), Expect = 9e-06, Method: Compositional matrix adjust. Identities = 32/99 (32%), Positives = 54/99 (54%), Gaps = 7/99 (7%) Query: 53 YDTTLVEKEGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAP 112 Y ++++K G+ L P DG PS+ +L+++K E+ G VHCV G+GR Sbjct: 50 YYLSILKKNGLQPLHIPIPDGGVPSD---SQFLTIMKWLLSEKEGNL--VHCVGGIGRTG 104 Query: 113 VLVALALI-EGGMKYEDAVQFIRQKRRGAFNS-KQLLYL 149 ++A LI G++ E A+ +R R GA + +Q ++L Sbjct: 105 TILASYLILTEGLEVESAIDEVRLVRPGAVQTYEQEMFL 143 >5BZX-A nrPDB Length = 314 Score = 44.3 bits (103), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 32/103 (31%), Positives = 48/103 (46%), Gaps = 20/103 (19%) Query: 45 IVRVC-EATYDTTLVEKEGIHVLDWPFDDGAPPSNQIV-------DDWLSLVKIKFREEP 96 I +C E YDT K V +PF+D PP +++ D WLS E+ Sbjct: 54 IYNLCAERHYDTA---KFNCRVAQYPFEDHNPPQLELIKPFCEDLDQWLS-------EDD 103 Query: 97 GCCIAVHCVAGLGRAPVLVALALIEGG--MKYEDAVQFIRQKR 137 A+HC AG GR V++ L+ G +K ++A+ F + R Sbjct: 104 NHVAAIHCKAGKGRTGVMICAYLLHRGKFLKAQEALDFYGEVR 146 >4BPC-A nrPDB Length = 582 Score = 43.5 bits (101), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 25/70 (35%), Positives = 39/70 (55%), Gaps = 4/70 (5%) Query: 67 DWPFDDGAPPSNQIVDDWLSLVKIKFREEPG--CCIAVHCVAGLGRAPVLVALALIEGGM 124 DWP + G P S + D++ V K +E+ G I+VHC AG+GR V + L+++ M Sbjct: 477 DWP-EQGVPKSGEGFIDFIGQVH-KTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERM 534 Query: 125 KYEDAVQFIR 134 +YE V + Sbjct: 535 RYEGVVDIFQ 544 >1LAR-A nrPDB Length = 575 Score = 42.0 bits (97), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 24/70 (34%), Positives = 38/70 (54%), Gaps = 4/70 (5%) Query: 67 DWPFDDGAPPSNQIVDDWLSLVKIKFREEPG--CCIAVHCVAGLGRAPVLVALALIEGGM 124 DWP + G P + + D++ V K +E+ G I VHC AG+GR V + L+++ M Sbjct: 470 DWP-EQGVPKTGEGFIDFIGQVH-KTKEQFGQDGPITVHCSAGVGRTGVFITLSIVLERM 527 Query: 125 KYEDAVQFIR 134 +YE V + Sbjct: 528 RYEGVVDMFQ 537 Score = 28.1 bits (61), Expect = 1.8, Method: Compositional matrix adjust. Identities = 21/72 (29%), Positives = 31/72 (43%), Gaps = 2/72 (2%) Query: 59 EKEGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALA 118 E + WP D G P + +L VK + G + VHC AG+GR + + Sbjct: 173 ELRQFQFMAWP-DHGVPEYPTPILAFLRRVKACNPLDAGPMV-VHCSAGVGRTGCFIVID 230 Query: 119 LIEGGMKYEDAV 130 + MK+E V Sbjct: 231 AMLERMKHEKTV 242 >5HDE-A nrPDB Length = 307 Score = 40.8 bits (94), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 27/92 (29%), Positives = 46/92 (50%), Gaps = 11/92 (11%) Query: 63 IHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALA---- 118 H ++WP D P S + D +SL++ K++E I +HC AG GR + A+ Sbjct: 198 FHYVNWP-DHDVPSSFDSILDMISLMR-KYQEHEDVPICIHCSAGCGRTGAICAIDYTWN 255 Query: 119 LIEGGMKYED-----AVQFIRQKRRGAFNSKQ 145 L++ G E+ +Q +R +R A +K+ Sbjct: 256 LLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKE 287 >3M4U-A nrPDB Length = 306 Score = 40.8 bits (94), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 31/85 (36%), Positives = 41/85 (48%), Gaps = 12/85 (14%) Query: 63 IHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLV----ALA 118 + + WP D G P S D+ LS++K P I VHC AG+GR L+ AL Sbjct: 192 VQYVGWP-DHGVPESAASFDELLSVIKNCVTTSP---ILVHCSAGIGRTGTLIGAYAALL 247 Query: 119 LIEGGMKYEDAVQFI----RQKRRG 139 IE G+ + V I +QKR G Sbjct: 248 HIERGILTDSTVYSIVAAMKQKRFG 272 >2H03-A nrPDB Length = 291 Score = 38.1 bits (87), Expect = 0.002, Method: Compositional matrix adjust. Identities = 22/69 (31%), Positives = 32/69 (46%), Gaps = 2/69 (2%) Query: 63 IHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCC-IAVHCVAGLGRAPVLVALALIE 121 H WP D G P + Q + ++ V+ PG VHC AG+GR +AL I Sbjct: 184 FHYTVWP-DHGVPETTQSLIQFVRTVRDYINRSPGAGPTVVHCSAGVGRTGTFIALDRIL 242 Query: 122 GGMKYEDAV 130 + +D+V Sbjct: 243 QQLDSKDSV 251 >3I36-A nrPDB Length = 342 Score = 36.6 bits (83), Expect = 0.005, Method: Compositional matrix adjust. Identities = 20/69 (28%), Positives = 35/69 (50%), Gaps = 2/69 (2%) Query: 63 IHVLDWPFDDGAPPSNQIVDDWLSLVKIKFRE-EPGCCIAVHCVAGLGRAPVLVALALIE 121 H WP D G P + ++ ++ LV+ ++ P I VHC AG+GR +A+ + Sbjct: 203 FHFTSWP-DHGVPDTTDLLINFRYLVRDYMKQIPPESPILVHCSAGVGRTGTFIAIDRLI 261 Query: 122 GGMKYEDAV 130 ++ E+ V Sbjct: 262 YQIENENTV 270 >2I75-A nrPDB Length = 320 Score = 36.6 bits (83), Expect = 0.006, Method: Compositional matrix adjust. Identities = 25/65 (38%), Positives = 35/65 (53%), Gaps = 10/65 (15%) Query: 63 IHVLDWPFDDGAPPSNQIVDDWLSLVKIK--FREEPGCCIAVHCVAGLGRAPVLV----A 116 I + WP D G P + D++ V+ K +EEP + VHC AG+GR VL+ A Sbjct: 205 IQYIAWP-DHGVPDDSSDFLDFVCHVRNKRAGKEEP---VVVHCSAGIGRTGVLITMETA 260 Query: 117 LALIE 121 + LIE Sbjct: 261 MCLIE 265 >4ERC-A nrPDB Length = 150 Score = 35.8 bits (81), Expect = 0.010, Method: Compositional matrix adjust. Identities = 26/85 (30%), Positives = 43/85 (50%), Gaps = 7/85 (8%) Query: 63 IHVLDWPFDDGAPPSNQIVDDWLSLV-KIKFREEPGCCIAVHCVAGLGRAPVLVALALI- 120 +H L P D PP+ +D ++ +V + R E + VHC G GR ++A L+ Sbjct: 58 LHRLRIP--DFCPPAPDQIDRFVQIVDEANARGE---AVGVHCALGFGRTGTMLACYLVK 112 Query: 121 EGGMKYEDAVQFIRQKRRGAFNSKQ 145 E G+ DA+ IR+ R G+ + + Sbjct: 113 ERGLAAGDAIAEIRRLRPGSIETYE 137 >6D3F-A nrPDB Length = 279 Score = 35.8 bits (81), Expect = 0.011, Method: Compositional matrix adjust. Identities = 24/81 (29%), Positives = 39/81 (48%), Gaps = 7/81 (8%) Query: 63 IHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALI-- 120 H WP + G P + + D ++ V+ + ++ I VHC AG GR +AL+ I Sbjct: 169 FHFHGWP-EIGIPAEGKGMIDLIAAVQKQQQQTGNHPITVHCSAGAGRTGTFIALSNILE 227 Query: 121 ----EGGMKYEDAVQFIRQKR 137 EG + AV+ +R +R Sbjct: 228 RVKAEGLLDVFQAVKSLRLQR 248 >2JJD-A nrPDB Length = 599 Score = 35.4 bits (80), Expect = 0.014, Method: Compositional matrix adjust. Identities = 24/81 (29%), Positives = 39/81 (48%), Gaps = 7/81 (8%) Query: 63 IHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALI-- 120 H WP + G P + + D ++ V+ + ++ I VHC AG GR +AL+ I Sbjct: 485 FHFHGWP-EIGIPAEGKGMIDLIAAVQKQQQQTGNHPITVHCSAGAGRTGTFIALSNILE 543 Query: 121 ----EGGMKYEDAVQFIRQKR 137 EG + AV+ +R +R Sbjct: 544 RVKAEGLLDVFQAVKSLRLQR 564 Score = 28.9 bits (63), Expect = 1.1, Method: Compositional matrix adjust. Identities = 23/78 (29%), Positives = 34/78 (43%), Gaps = 5/78 (6%) Query: 63 IHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALIEG 122 +H WP D G P + + +L VK G I VHC AG+GR + + + Sbjct: 191 LHFTSWP-DFGVPFTPIGMLKFLKKVKTLNPVHAGP-IVVHCSAGVGRTGTFIVIDAMMA 248 Query: 123 GMKYE---DAVQFIRQKR 137 M E D +F+ + R Sbjct: 249 MMHAEQKVDVFEFVSRIR 266 >2QEP-A nrPDB Length = 304 Score = 35.0 bits (79), Expect = 0.017, Method: Compositional matrix adjust. Identities = 26/90 (28%), Positives = 42/90 (46%), Gaps = 9/90 (10%) Query: 63 IHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALI-- 120 H L W +D G P S++ + D+ V +R C I VHC G GR+ V + ++ Sbjct: 193 FHFLSW-YDRGVPSSSRSLLDFRRKVNKCYRGR-SCPIIVHCSDGAGRSGTYVLIDMVLN 250 Query: 121 --EGGMKYED---AVQFIRQKRRGAFNSKQ 145 G K D ++ +R +R G +K+ Sbjct: 251 KMAKGAKEIDIAATLEHLRDQRPGMVQTKE 280 >2C46-A nrPDB Length = 241 Score = 35.0 bits (79), Expect = 0.018, Method: Compositional matrix adjust. Identities = 25/96 (26%), Positives = 42/96 (43%), Gaps = 2/96 (2%) Query: 28 ATLNKFIEELK-KYGVTTIVRVCEATYDTTLVEKEGIHVLDWPFDD-GAPPSNQIVDDWL 85 + L+ +++ LK K G+ + YD +EKEGI + G P+ + + ++ Sbjct: 70 SMLSNYLKSLKVKMGLLVDLTNTSRFYDRNDIEKEGIKYIKLQCKGHGECPTTENTETFI 129 Query: 86 SLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALIE 121 L + P I VHC G R L+ L+E Sbjct: 130 RLCERFNERNPPELIGVHCTHGFNRTGFLICAFLVE 165 >2R0B-A nrPDB Length = 154 Score = 34.7 bits (78), Expect = 0.019, Method: Compositional matrix adjust. Identities = 29/124 (23%), Positives = 57/124 (45%), Gaps = 20/124 (16%) Query: 25 PTNATLNKFIEELKKYGVTTIVRV---CEATYD----TTLVEKEGIHVLDWPFDD---GA 74 P ++ + + L+K+G+T I+ + EA + L + + D P ++ Sbjct: 17 PYSSAMKSKLPVLQKHGITHIICIRQNIEANFIKPNFQQLFRYLVLDIADNPVENIIRFF 76 Query: 75 PPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALIEG-GMKYEDAVQFI 133 P + + +D L + G + VH AG+ R+ V ++E GMKY DA ++ Sbjct: 77 PMTKEFIDGSLQM---------GGKVLVHGNAGISRSAAFVIAYIMETFGMKYRDAFAYV 127 Query: 134 RQKR 137 +++R Sbjct: 128 QERR 131 >3V0J-A nrPDB Length = 334 Score = 34.3 bits (77), Expect = 0.031, Method: Compositional matrix adjust. Identities = 27/100 (27%), Positives = 44/100 (44%), Gaps = 6/100 (6%) Query: 45 IVRVC-EATYDTTLVEKEGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVH 103 I +C E YD T + HV DD P+ + ++ K+ +P IA+H Sbjct: 69 IYNLCSERGYDETKFDN---HVYRVMIDDHNVPTLVDLLKFIDDAKVWMTSDPDHVIAIH 125 Query: 104 CVAGLGRAPVLVALALIEGGM--KYEDAVQFIRQKRRGAF 141 G GR LV+ L+E G ++A+++ +R F Sbjct: 126 SKGGKGRTGTLVSSWLLEDGKFDTAKEALEYFGSRRTDVF 165 >4YR8-G nrPDB Length = 167 Score = 34.3 bits (77), Expect = 0.032, Method: Compositional matrix adjust. Identities = 14/40 (35%), Positives = 26/40 (65%), Gaps = 1/40 (2%) Query: 99 CIAVHCVAGLGR-APVLVALALIEGGMKYEDAVQFIRQKR 137 C+ VHC+AG+ R A + +A + M ++A +F+++KR Sbjct: 105 CVLVHCLAGISRSATIAIAYIMKRMDMSLDEAYRFVKEKR 144 >2I1Y-A nrPDB Length = 301 Score = 33.9 bits (76), Expect = 0.040, Method: Compositional matrix adjust. Identities = 26/89 (29%), Positives = 40/89 (44%), Gaps = 9/89 (10%) Query: 63 IHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALI-- 120 H L WP + G P S + + D+ V +R C I VHC G GR + + ++ Sbjct: 192 FHFLSWPAE-GTPASTRPLLDFRRKVNKCYRGR-SCPIIVHCSDGAGRTGTYILIDMVLN 249 Query: 121 --EGGMKYED---AVQFIRQKRRGAFNSK 144 G+K D ++ +R +R G SK Sbjct: 250 RMAKGVKEIDIAATLEHVRDQRPGLVRSK 278 >1WRM-A nrPDB Length = 165 Score = 33.9 bits (76), Expect = 0.040, Method: Compositional matrix adjust. Identities = 35/110 (31%), Positives = 49/110 (44%), Gaps = 12/110 (10%) Query: 35 EELKKYGVTTIVRVCEATYDTTLVEKEGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFRE 94 E+L K VT I+ V +D+ EG+ L P D PS + + IKF Sbjct: 26 EQLSKNKVTHILSV----HDSARPMLEGVKYLCIPAADS--PSQNLTRHFKE--SIKFIH 77 Query: 95 E---PGCCIAVHCVAGLGRAPVLV-ALALIEGGMKYEDAVQFIRQKRRGA 140 E G VHC+AG+ R+ LV A + +EDA+ +R R A Sbjct: 78 ECRLRGESCLVHCLAGVSRSVTLVIAYIMTVTDFGWEDALHTVRAGRSCA 127 >4AZ1-A nrPDB Length = 302 Score = 33.5 bits (75), Expect = 0.047, Method: Compositional matrix adjust. Identities = 27/85 (31%), Positives = 39/85 (45%), Gaps = 12/85 (14%) Query: 63 IHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLV----ALA 118 + WP D G P S ++ L+ VK P + VHC AG+GR L+ AL Sbjct: 189 VQYTGWP-DHGIPQSATSLEALLTNVKNSPTTVP---VVVHCSAGIGRTGTLIGAYAALT 244 Query: 119 LIEGGMKYE----DAVQFIRQKRRG 139 +E G + D V +R++R G Sbjct: 245 HLERGTLTDTTVYDVVSAMRRQRFG 269 >1WCH-A nrPDB Length = 315 Score = 33.1 bits (74), Expect = 0.072, Method: Compositional matrix adjust. Identities = 25/83 (30%), Positives = 37/83 (44%), Gaps = 10/83 (12%) Query: 68 WPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVL----VALALIEGG 123 WP D PS DD L+ + I HC AG+GR+ L V L LI Sbjct: 214 WP--DHDTPSQP--DDLLTFISYMRHIHRSGPIITHCSAGIGRSGTLICIDVVLGLISQD 269 Query: 124 MKYE--DAVQFIRQKRRGAFNSK 144 + ++ D V+ +R +R G ++ Sbjct: 270 LDFDISDLVRCMRLQRHGMVQTE 292 >2GJT-A nrPDB Length = 295 Score = 32.7 bits (73), Expect = 0.075, Method: Compositional matrix adjust. Identities = 27/99 (27%), Positives = 42/99 (42%), Gaps = 16/99 (16%) Query: 33 FIEELKKYGVTTIVRVCEATYDTTLVEKEGIHVLD------------WPFDDGAPPSN-- 78 F EE YG T+ + E D I+ D WP D G P +N Sbjct: 140 FTEEPIAYGDITVEMISEEEQDDWACRHFRINYADEMQDVMHFNYTAWP-DHGVPTANAA 198 Query: 79 QIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVAL 117 + + ++ +V+ + + G I +HC AG+GR +AL Sbjct: 199 ESILQFVHMVRQQATKSKGPMI-IHCSAGVGRTGTFIAL 236 >3LJ8-A nrPDB Length = 146 Score = 32.7 bits (73), Expect = 0.077, Method: Compositional matrix adjust. Identities = 29/114 (25%), Positives = 47/114 (41%), Gaps = 21/114 (18%) Query: 34 IEELKKYGVTTIVRVCEATYDTTLVEKEG-IHVLDWPFDDG--------APPSNQIVDDW 84 +E L K G+ I+ V EK G H P D P + + +D+ Sbjct: 21 LESLAKLGIRYILNVTPNL--PNFFEKNGDFHYKQIPISDHWSQNLSRFFPEAIEFIDEA 78 Query: 85 LSLVKIKFREEPGCCIAVHCVAGLGRA-PVLVALALIEGGMKYEDAVQFIRQKR 137 LS C + VHC+AG+ R+ V VA + + + DA +++K+ Sbjct: 79 LS---------QNCGVLVHCLAGVSRSVTVTVAYLMQKLHLSLNDAYDLVKRKK 123 >4JMK-A nrPDB Length = 152 Score = 32.7 bits (73), Expect = 0.087, Method: Compositional matrix adjust. Identities = 14/42 (33%), Positives = 25/42 (59%), Gaps = 1/42 (2%) Query: 97 GCCIAVHCVAGLGR-APVLVALALIEGGMKYEDAVQFIRQKR 137 C + VH +AG+ R A + +A + GM +DA +F++ +R Sbjct: 81 SCQVIVHSLAGISRSATIAIAYIMKTMGMSSDDAYRFVKDRR 122 >1I9T-A nrPDB Length = 210 Score = 32.3 bits (72), Expect = 0.11, Method: Compositional matrix adjust. Identities = 29/113 (25%), Positives = 46/113 (40%), Gaps = 3/113 (2%) Query: 28 ATLNKFIEELK-KYGVTTIVRVCEATYDTTLVEKEGIHVLDWPFDD-GAPPSNQIVDDWL 85 + L+ +++ LK K + + YD +EKEGI + G P+ + + ++ Sbjct: 48 SMLSNYLKSLKVKMSLLVDLTNTSRFYDRNDIEKEGIKYIKLQCKGHGECPTTENTETFI 107 Query: 86 SLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALIEG-GMKYEDAVQFIRQKR 137 L + P I VHC G R L+ L+E E AV Q R Sbjct: 108 RLCERFNERSPPELIGVHCTHGFNRTGFLICAFLVEKMDWSIEAAVATFAQAR 160 >2CFV-A nrPDB Length = 316 Score = 32.3 bits (72), Expect = 0.12, Method: Compositional matrix adjust. Identities = 17/61 (27%), Positives = 32/61 (52%), Gaps = 1/61 (1%) Query: 71 DDGAPPSNQIVDDWLSLVKIKFREEP-GCCIAVHCVAGLGRAPVLVALALIEGGMKYEDA 129 D G P + ++ ++ LV+ ++ P I VHC AG+GR +A+ + ++ E+ Sbjct: 210 DHGVPDTTDLLINFRYLVRDYMKQSPPESPILVHCSAGVGRTGTFIAIDRLIYQIENENT 269 Query: 130 V 130 V Sbjct: 270 V 270 >4H1O-A nrPDB Length = 560 Score = 32.0 bits (71), Expect = 0.15, Method: Compositional matrix adjust. Identities = 32/91 (35%), Positives = 38/91 (41%), Gaps = 17/91 (18%) Query: 37 LKKYGVTTIVRVCE-ATYDTTLVE----KEG----------IHVLDWPFDDGAPPSNQIV 81 LK+YGV + V E A +D TL E K G H WP D G P V Sbjct: 398 LKEYGVMRVRNVKESAAHDYTLRELKLSKVGQGNTERTVWQYHFRTWP-DHGVPSDPGGV 456 Query: 82 DDWLSLVKIKFRE-EPGCCIAVHCVAGLGRA 111 D+L V K + VHC AG+GR Sbjct: 457 LDFLEEVHHKQESIMDAGPVVVHCSAGIGRT 487 >4PVG-A nrPDB Length = 298 Score = 31.6 bits (70), Expect = 0.16, Method: Compositional matrix adjust. Identities = 36/133 (27%), Positives = 53/133 (39%), Gaps = 26/133 (19%) Query: 37 LKKYGVTTIVRVCE-ATYDTTLVE----KEG----------IHVLDWPFDDGAPPSNQIV 81 LK+YGV + V E A +D TL E K G H WP D G P V Sbjct: 139 LKEYGVMRVRNVKESAAHDYTLRELKLSKVGQGNTERTVWQYHFRTWP-DHGVPSDPGGV 197 Query: 82 DDWLSLVKIKFRE-EPGCCIAVHCVAGLGRAPVLVALAL---------IEGGMKYEDAVQ 131 D+L V K + VHC AG+GR + + + ++ + +Q Sbjct: 198 LDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQ 257 Query: 132 FIRQKRRGAFNSK 144 +R +R G ++ Sbjct: 258 MVRSQRSGMVQTE 270 >5OVR-A nrPDB Length = 305 Score = 31.6 bits (70), Expect = 0.17, Method: Compositional matrix adjust. Identities = 25/86 (29%), Positives = 38/86 (44%), Gaps = 13/86 (15%) Query: 68 WPFD---DGAPPSNQIVDDWLSLVKIKFREEPGCC-IAVHCVAGLGRAPVLVALALIEGG 123 WP D APP +V + + + +E P C I VHC AG+GR +A ++ Sbjct: 201 WPDQKTPDRAPPLLHLVRE---VEEAAQQEGPHCAPIIVHCSAGIGRTGCFIATSICCQQ 257 Query: 124 MKYEDAVQF------IRQKRRGAFNS 143 ++ E V +RQ R G + Sbjct: 258 LRQEGVVDILKTTCQLRQDRGGMIQT 283 >2B3O-A nrPDB Length = 532 Score = 31.6 bits (70), Expect = 0.17, Method: Compositional matrix adjust. Identities = 21/89 (23%), Positives = 38/89 (42%), Gaps = 11/89 (12%) Query: 66 LDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCC-IAVHCVAGLGRAPVLVALAL----- 119 L WP D G P V +L + + P I VHC AG+GR ++ + + Sbjct: 415 LSWP-DHGVPSEPGGVLSFLDQINQRQESLPHAGPIIVHCSAGIGRTGTIIVIDMLMENI 473 Query: 120 ----IEGGMKYEDAVQFIRQKRRGAFNSK 144 ++ + + +Q +R +R G ++ Sbjct: 474 STKGLDCDIDIQKTIQMVRAQRSGMVQTE 502 >6H8S-A nrPDB Length = 301 Score = 31.6 bits (70), Expect = 0.18, Method: Compositional matrix adjust. Identities = 25/87 (28%), Positives = 38/87 (43%), Gaps = 13/87 (14%) Query: 67 DWP---FDDGAPPSNQIVDDWLSLVKIKFREEPGCC-IAVHCVAGLGRAPVLVALALIEG 122 WP D APP +V + + + +E P C I VHC AG+GR +A ++ Sbjct: 196 SWPDQKTPDRAPPLLHLVRE---VEEAAQQEGPHCSPIIVHCSAGIGRTGCFIATSICCQ 252 Query: 123 GMKYEDAVQF------IRQKRRGAFNS 143 ++ E V +RQ R G + Sbjct: 253 QLRREGVVDILKTTCQLRQDRGGMIQT 279 >3F41-A nrPDB Length = 629 Score = 31.6 bits (70), Expect = 0.18, Method: Compositional matrix adjust. Identities = 20/73 (27%), Positives = 32/73 (43%), Gaps = 5/73 (6%) Query: 46 VRVCEATYDTTLVEKEGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPG-CCIAVHC 104 V++ + LVEK G+H D PS +D++++ R P + HC Sbjct: 482 VKIESVMTEQQLVEKNGLHYYRIAATDHIWPSAANIDEFINFT----RTMPANAWLHFHC 537 Query: 105 VAGLGRAPVLVAL 117 AG GR +A+ Sbjct: 538 QAGAGRTTAYMAM 550 Score = 28.5 bits (62), Expect = 1.6, Method: Compositional matrix adjust. Identities = 25/110 (22%), Positives = 47/110 (42%), Gaps = 18/110 (16%) Query: 57 LVEKEGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVA 116 +V++ G + D P + VD +L K ++ + HC AG+GR + + Sbjct: 195 MVKQHGANYFRLTLQDHFRPDDPDVDKFLEFYKSLPKD---AWLHYHCYAGMGRTTIFMV 251 Query: 117 LALIEGGMK---YEDAVQFIRQKRRGAFNSKQL----------LYLEKYR 153 + I K ++D +Q RQK G + ++ Y+E+Y+ Sbjct: 252 MHDILKNAKDVSFDDIIQ--RQKLIGIVDLSEIPDKKKNYGRKAYIERYQ 299 >6CMQ-A nrPDB Length = 427 Score = 31.6 bits (70), Expect = 0.20, Method: Compositional matrix adjust. Identities = 36/133 (27%), Positives = 53/133 (39%), Gaps = 26/133 (19%) Query: 37 LKKYGVTTIVRVCE-ATYDTTLVE----KEG----------IHVLDWPFDDGAPPSNQIV 81 LK+YGV + V E A +D TL E K G H WP D G P V Sbjct: 275 LKEYGVMRVRNVKESAAHDYTLRELKLSKVGQGNTERTVWQYHFRTWP-DHGVPSDPGGV 333 Query: 82 DDWLSLVKIKFRE-EPGCCIAVHCVAGLGRAPVLVALAL---------IEGGMKYEDAVQ 131 D+L V K + VHC AG+GR + + + ++ + +Q Sbjct: 334 LDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQ 393 Query: 132 FIRQKRRGAFNSK 144 +R +R G ++ Sbjct: 394 MVRSQRSGMVQTE 406 >2PI7-A nrPDB Length = 312 Score = 31.6 bits (70), Expect = 0.20, Method: Compositional matrix adjust. Identities = 18/52 (34%), Positives = 29/52 (55%), Gaps = 4/52 (7%) Query: 68 WPFDDGAPPSN--QIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVAL 117 WP D G P +N + + ++ +V+ K + G I +HC AG+GR +AL Sbjct: 196 WP-DHGVPTANAAESILQFVQMVRQKSVKSKGPMI-IHCSAGVGRTGTFIAL 245 >2BZL-A nrPDB Length = 325 Score = 31.2 bits (69), Expect = 0.21, Method: Compositional matrix adjust. Identities = 33/116 (28%), Positives = 48/116 (41%), Gaps = 27/116 (23%) Query: 39 KYGVTTIVRVCEATYDTTLV---------EKEGIHV--LDWPFDDGAPPSNQIVDDWLSL 87 K+ VTT R Y TT + E+ H+ DWP D G P Q +L Sbjct: 175 KFKVTTKFRTDSVCYATTGLKVKHLLSGQERTVWHLQYTDWP-DHGCPEDVQGFLSYLEE 233 Query: 88 VK------------IKFREEPGCCIAVHCVAGLGRAPVLVALALIEGGMKYEDAVQ 131 ++ K R P I VHC AG+GR VL+ L+ +++ + V+ Sbjct: 234 IQSVRRHTNSMLEGTKNRHPP---IVVHCSAGVGRTGVLILSELMIYCLEHNEKVE 286 >4GE6-A nrPDB Length = 314 Score = 31.2 bits (69), Expect = 0.21, Method: Compositional matrix adjust. Identities = 28/105 (26%), Positives = 43/105 (40%), Gaps = 19/105 (18%) Query: 63 IHVLDWPFDDGAPPSNQIVDDWLSLVK---------IKFREEPGCC---IAVHCVAGLGR 110 L WP D G P S + D+L +V+ + R + C I VHC AG+GR Sbjct: 188 FQFLSWP-DYGVPSSAASLIDFLRVVRNQQSLAVSNMGARSKGQCPEPPIVVHCSAGIGR 246 Query: 111 APVL----VALALIE--GGMKYEDAVQFIRQKRRGAFNSKQLLYL 149 + LA +E G + V +R +R + + + Y Sbjct: 247 TGTFCSLDICLAQLEELGTLNVFQTVSRMRTQRAFSIQTPEQYYF 291 >1P15-A nrPDB Length = 253 Score = 31.2 bits (69), Expect = 0.22, Method: Compositional matrix adjust. Identities = 21/78 (26%), Positives = 36/78 (46%), Gaps = 4/78 (5%) Query: 63 IHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALIEG 122 H WP + G P + + + ++ V+ + ++ I VHC AG GR AL+ + Sbjct: 143 FHFHGWP-EVGIPSDGKGMINIIAAVQKQQQQSGNHPITVHCSAGAGRTGTFCALSTVLE 201 Query: 123 GMKYE---DAVQFIRQKR 137 +K E D Q ++ R Sbjct: 202 RVKAEGILDVFQTVKSLR 219 >6DR7-A nrPDB Length = 306 Score = 31.2 bits (69), Expect = 0.23, Method: Compositional matrix adjust. Identities = 24/95 (25%), Positives = 37/95 (38%), Gaps = 19/95 (20%) Query: 63 IHVLDWPFDDGAPPSN------QIVDDWLSLVKIKFREEPGCCIA--------VHCVAGL 108 +HV WP D G P S +VD + + + +A +HC AG+ Sbjct: 187 VHVTTWP-DFGVPESEVTKALASLVDQTAETKRNMYESKGSSAVADDSKLRPVIHCRAGV 245 Query: 109 GRAPVLVALALIEGG----MKYEDAVQFIRQKRRG 139 GR L+ + + ED V +R +R G Sbjct: 246 GRTAQLIGAMCMNDSRNSQLSVEDMVSQMRVQRNG 280 >1YN9-A nrPDB Length = 169 Score = 30.8 bits (68), Expect = 0.35, Method: Compositional matrix adjust. Identities = 17/63 (26%), Positives = 30/63 (47%), Gaps = 1/63 (1%) Query: 76 PSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALIEG-GMKYEDAVQFIR 134 P IV +++ VK + PG + VHC G+ R +V L+ G+ ++A+ Sbjct: 92 PPESIVQEFIDTVKEFTEKCPGMLVGVHCTHGINRTGYMVCRYLMHTLGIAPQEAIDRFE 151 Query: 135 QKR 137 + R Sbjct: 152 KAR 154 >4BJO-A nrPDB Length = 338 Score = 30.0 bits (66), Expect = 0.48, Method: Compositional matrix adjust. Identities = 30/93 (32%), Positives = 39/93 (41%), Gaps = 15/93 (16%) Query: 26 TNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEKEGIHV--LDWPFDDGAPPSNQIVDD 83 TN L E++K Y VR E TT +E +H WP D G P S + Sbjct: 155 TNLKLTLISEDIKSY---YTVRQLELENLTTQETREILHFHYTTWP-DFGVPESPASFLN 210 Query: 84 WLSLVKIKFREEPGCC-----IAVHCVAGLGRA 111 +L K RE + VHC AG+GR+ Sbjct: 211 FL----FKVRESGSLSPEHGPVVVHCSAGIGRS 239 >3S3F-A nrPDB Length = 307 Score = 30.0 bits (66), Expect = 0.55, Method: Compositional matrix adjust. Identities = 24/73 (32%), Positives = 31/73 (42%), Gaps = 12/73 (16%) Query: 63 IHVLDWPFDDGAPPSNQIVDDWLSLVKI--KFREEPGC---CIAVHCVAGLGRAPVLVAL 117 H WP D G P Q +LV+ FR+ G I VHC AG+GR+ + L Sbjct: 203 FHFTTWP-DFGVPNPPQ------TLVRFVRAFRDRIGAEQRPIVVHCSAGVGRSGTFITL 255 Query: 118 ALIEGGMKYEDAV 130 I + D V Sbjct: 256 DRILQQINTSDYV 268 >1ZZW-A nrPDB Length = 149 Score = 30.0 bits (66), Expect = 0.55, Method: Compositional matrix adjust. Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 1/42 (2%) Query: 97 GCCIAVHCVAGLGR-APVLVALALIEGGMKYEDAVQFIRQKR 137 G + +HC AG+ R A +++A + M DA +F++ KR Sbjct: 83 GKGLLIHCQAGVSRSATIVIAYLMKHTRMTMTDAYKFVKGKR 124 >2OUD-A nrPDB Length = 177 Score = 30.0 bits (66), Expect = 0.60, Method: Compositional matrix adjust. Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 1/42 (2%) Query: 97 GCCIAVHCVAGLGR-APVLVALALIEGGMKYEDAVQFIRQKR 137 G + +HC AG+ R A +++A + M DA +F++ KR Sbjct: 87 GKGLLIHCQAGVSRSATIVIAYLMKHTRMTMTDAYKFVKGKR 128 >2C7S-A nrPDB Length = 313 Score = 29.6 bits (65), Expect = 0.74, Method: Compositional matrix adjust. Identities = 24/85 (28%), Positives = 38/85 (44%), Gaps = 8/85 (9%) Query: 59 EKEGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRA------P 112 E + H WP D G P + ++ VK+ G I VHC AG GR Sbjct: 198 EVKQFHFTGWP-DHGVPYHATGLLSFIRRVKLSNPPSAGP-IVVHCSAGAGRTGCYIVID 255 Query: 113 VLVALALIEGGMKYEDAVQFIRQKR 137 +++ +A EG + + V+ +R +R Sbjct: 256 IMLDMAEREGVVDIYNCVKALRSRR 280 >1RPM-A nrPDB Length = 278 Score = 29.6 bits (65), Expect = 0.79, Method: Compositional matrix adjust. Identities = 28/105 (26%), Positives = 44/105 (41%), Gaps = 17/105 (16%) Query: 48 VCEATYDTTLVEKEGIHVL---------DWPFDDGAPPSNQIVDDWLSLVKIKFREEPGC 98 + E T VEK G+H + WP D G P + ++ VK K G Sbjct: 154 LAEYVIRTFAVEKRGVHEIREIRQFHFTGWP-DHGVPYHATGLLGFVRQVKSKSPPSAGP 212 Query: 99 CIAVHCVAGLGRAPVLVALALI------EGGMKYEDAVQFIRQKR 137 + VHC AG GR + + ++ EG + + V+ +R +R Sbjct: 213 LV-VHCSAGAGRTGCFIVIDIMLDMAEREGVVDIYNCVRELRSRR 256 >4Y2E-A nrPDB Length = 149 Score = 28.9 bits (63), Expect = 1.0, Method: Compositional matrix adjust. Identities = 13/41 (31%), Positives = 24/41 (58%), Gaps = 1/41 (2%) Query: 98 CCIAVHCVAGLGRA-PVLVALALIEGGMKYEDAVQFIRQKR 137 C + VH +AG+ R+ V VA + + + DA F+++K+ Sbjct: 86 CGVLVHSLAGISRSVTVTVAYLMQKMNLSLNDAYDFVKRKK 126 >6D4D-A nrPDB Length = 292 Score = 28.9 bits (63), Expect = 1.1, Method: Compositional matrix adjust. Identities = 23/78 (29%), Positives = 34/78 (43%), Gaps = 5/78 (6%) Query: 63 IHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALIEG 122 +H WP D G P + + +L VK G I VHC AG+GR + + + Sbjct: 190 LHFTSWP-DFGVPFTPIGMLKFLKKVKTLNPVHAGP-IVVHCSAGVGRTGTFIVIDAMMA 247 Query: 123 GMKYE---DAVQFIRQKR 137 M E D +F+ + R Sbjct: 248 MMHAEQKVDVFEFVSRIR 265 >2Y96-A nrPDB Length = 219 Score = 28.9 bits (63), Expect = 1.1, Method: Compositional matrix adjust. Identities = 23/58 (39%), Positives = 29/58 (50%), Gaps = 8/58 (13%) Query: 100 IAVHCVAGLGRAPVLV-ALALIEGGMKYEDAVQFIRQKR-----RGAFNSKQLLYLEK 151 I VHCV G R+ LV A +I M DA+Q + + R RG KQL L+K Sbjct: 142 ILVHCVMGRSRSATLVLAYLMIHKDMTLVDAIQQVAKNRCVLPNRGFL--KQLRELDK 197 >2A8B-A nrPDB Length = 283 Score = 28.9 bits (63), Expect = 1.1, Method: Compositional matrix adjust. Identities = 30/110 (27%), Positives = 46/110 (41%), Gaps = 15/110 (13%) Query: 46 VRVCEATYDTTLVEKEGIHV--------LDWPFDDGAPPSNQ-IVDDWLSLVKIKFREEP 96 V C+ LV K+G H WP D P S Q ++ L + + + + Sbjct: 150 VNECDNYTIRNLVLKQGSHTQHVKHYWYTSWP-DHKTPDSAQPLLQLMLDVEEDRLASQG 208 Query: 97 GCCIAVHCVAGLGRAPVLVALALIEGGMKYE---DAVQFIRQKR--RGAF 141 + VHC AG+GR +A ++ +K E DA+ + Q R RG Sbjct: 209 RGPVVVHCSAGIGRTGCFIATSIGCQQLKEEGVVDALSIVCQLRMDRGGM 258 >3OLR-A nrPDB Length = 313 Score = 28.9 bits (63), Expect = 1.1, Method: Compositional matrix adjust. Identities = 22/84 (26%), Positives = 39/84 (46%), Gaps = 6/84 (7%) Query: 36 ELKKYGVTTIVRVCEATYDTTLVEKEGIHVLDWPFDDGAPPSNQIVDDWLSLV-KIK-FR 93 E +K I+R + +++ H +WP D P S +D L L+ ++ ++ Sbjct: 180 EAEKRKSDYIIRTLKVKFNSETRTIYQFHYKNWP-DHDVPSS---IDPILELIWDVRCYQ 235 Query: 94 EEPGCCIAVHCVAGLGRAPVLVAL 117 E+ I +H AG GR V+ A+ Sbjct: 236 EDDSVPICIHSSAGCGRTGVICAI 259 >1YFO-A nrPDB Length = 302 Score = 28.5 bits (62), Expect = 1.7, Method: Compositional matrix adjust. Identities = 22/68 (32%), Positives = 29/68 (42%), Gaps = 2/68 (2%) Query: 63 IHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALIEG 122 H WP D G P + + +L VK + G I VHC AG+GR V + + Sbjct: 193 FHFTSWP-DFGVPFTPIGMLKFLKKVKACNPQYAGA-IVVHCSAGVGRTGTFVVIDAMLD 250 Query: 123 GMKYEDAV 130 M E V Sbjct: 251 MMHSERKV 258 >2OOQ-A nrPDB Length = 286 Score = 28.1 bits (61), Expect = 2.1, Method: Compositional matrix adjust. Identities = 19/55 (34%), Positives = 24/55 (43%), Gaps = 2/55 (3%) Query: 63 IHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVAL 117 H WP D G P + ++ VK E G I VHC AG GR +A+ Sbjct: 180 FHFTSWP-DHGVPCYATGLLGFVRQVKFLNPPEAGP-IVVHCSAGAGRTGCFIAI 232 >5AWX-A nrPDB Length = 298 Score = 28.1 bits (61), Expect = 2.1, Method: Compositional matrix adjust. Identities = 19/67 (28%), Positives = 29/67 (43%), Gaps = 2/67 (2%) Query: 64 HVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALIEGG 123 H WP D G P + V ++ R G + VHC AG+GR + L + Sbjct: 193 HYTQWP-DMGVPEYSLPVLTFVRKAAYAKRHAVGPVV-VHCSAGVGRTGTYIVLDSMLQQ 250 Query: 124 MKYEDAV 130 +++E V Sbjct: 251 IQHEGTV 257 >5XJV-A nrPDB Length = 185 Score = 27.7 bits (60), Expect = 2.4, Method: Compositional matrix adjust. Identities = 15/43 (34%), Positives = 22/43 (51%), Gaps = 1/43 (2%) Query: 96 PGCCIAVHCVAGLGRAPVLV-ALALIEGGMKYEDAVQFIRQKR 137 PG + VH V G+ R+ LV A ++ + AV +RQ R Sbjct: 121 PGAKVLVHSVVGVSRSATLVLAYLMLHQRLSLRQAVITVRQHR 163 >1UPI-A nrPDB Length = 225 Score = 27.7 bits (60), Expect = 2.6, Method: Compositional matrix adjust. Identities = 13/39 (33%), Positives = 21/39 (53%), Gaps = 4/39 (10%) Query: 43 TTIVRVCEATYDT----TLVEKEGIHVLDWPFDDGAPPS 77 +T++ +C A Y+ T+ + +DWP DGA PS Sbjct: 148 STVMYLCSAEYNPQREHTICATDPTLAVDWPLVDGAAPS 186 >1PM7-A nrPDB Length = 202 Score = 27.7 bits (60), Expect = 2.7, Method: Compositional matrix adjust. Identities = 13/39 (33%), Positives = 21/39 (53%), Gaps = 4/39 (10%) Query: 43 TTIVRVCEATYDT----TLVEKEGIHVLDWPFDDGAPPS 77 +T++ +C A Y+ T+ + +DWP DGA PS Sbjct: 128 STVMYLCSAEYNPQREHTICATDPTLAVDWPLVDGAAPS 166 >3EZZ-A nrPDB Length = 144 Score = 27.3 bits (59), Expect = 3.3, Method: Compositional matrix adjust. Identities = 12/39 (30%), Positives = 26/39 (66%), Gaps = 1/39 (2%) Query: 100 IAVHCVAGLGR-APVLVALALIEGGMKYEDAVQFIRQKR 137 + VH AG+ R A + +A +++ ++ E+A +F++Q+R Sbjct: 84 VLVHSQAGISRSATICLAYLMMKKRVRLEEAFEFVKQRR 122 >3RGQ-A nrPDB Length = 156 Score = 27.3 bits (59), Expect = 3.4, Method: Compositional matrix adjust. Identities = 19/65 (29%), Positives = 33/65 (50%), Gaps = 2/65 (3%) Query: 97 GCCIAVHCVAGLGRAPVLVALALIE-GGMKYEDAVQFIRQKRRG-AFNSKQLLYLEKYRP 154 G C+ VH AG R+ +VA LI+ E+A++ I + R + QL L+++ Sbjct: 90 GQCVYVHSKAGRSRSATMVAAYLIQVHNWSPEEAIEAIAKIRSHISIRPSQLEVLKEFHK 149 Query: 155 KMRLR 159 ++ R Sbjct: 150 EITAR 154 >4KYQ-A nrPDB Length = 208 Score = 27.3 bits (59), Expect = 3.8, Method: Compositional matrix adjust. Identities = 10/13 (76%), Positives = 11/13 (84%) Query: 100 IAVHCVAGLGRAP 112 + VHC AGLGRAP Sbjct: 115 VYVHCSAGLGRAP 127 >5CG0-A nrPDB Length = 489 Score = 26.9 bits (58), Expect = 4.3, Method: Compositional matrix adjust. Identities = 28/100 (28%), Positives = 44/100 (44%), Gaps = 8/100 (8%) Query: 24 NPTN-ATLNKFIEELKKYGVTTIVRVCEATYDTTLVEKEGIH---VLDWPFDDGAPPSNQ 79 NP A N +I+E+ KY +T ++ + L E G + DW F+D A + Sbjct: 95 NPAGIAFYNNYIDEMLKYNITPLITLYHWDLPQKLQELGGFANPLISDW-FEDYARVVFE 153 Query: 80 IVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALAL 119 D + + I F E C + A +AP+L A A+ Sbjct: 154 NFGDRVKMF-ITFNEPREICFEGYGSA--TKAPILNATAM 190 >2CU0-A nrPDB Length = 486 Score = 26.9 bits (58), Expect = 4.4, Method: Compositional matrix adjust. Identities = 25/87 (28%), Positives = 38/87 (43%), Gaps = 3/87 (3%) Query: 36 ELKKYGVTTIVRVCEATYDTTLVE--KEGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFR 93 EL K GV IV ++ ++ KE +D F G + + VDD +K Sbjct: 235 ELDKAGVDVIVVDTAHAHNLKAIKSMKEMRQKVDADFIVGNIANPKAVDDLTFADAVKVG 294 Query: 94 EEPGCCIAVHCVAGLGRAPVLVALALI 120 PG VAG+G P + A+A++ Sbjct: 295 IGPGSICTTRIVAGVG-VPQITAVAMV 320 >4PDK-A nrPDB Length = 279 Score = 26.6 bits (57), Expect = 5.4, Method: Compositional matrix adjust. Identities = 18/61 (29%), Positives = 30/61 (49%), Gaps = 1/61 (1%) Query: 26 TNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEKEGIHVLDWPFDDGAPPSNQIVDDWL 85 T TL + ++ L + G TI + + T +E G+H+LD A + IV+D L Sbjct: 44 TRTTLREVLQRLARDGWLTI-QHGKPTKVNQFMETSGLHILDTLMTLDAENATSIVEDLL 102 Query: 86 S 86 + Sbjct: 103 A 103 >2NV5-A nrPDB Length = 299 Score = 26.6 bits (57), Expect = 5.7, Method: Compositional matrix adjust. Identities = 32/112 (28%), Positives = 43/112 (38%), Gaps = 11/112 (9%) Query: 22 THNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEKEGIHVLD---WPFDDGAPPSN 78 TH TL +E L Y V T A Y EK + WP D G P Sbjct: 148 THGLVQVTLLDTVE-LATYCVRTF-----ALYKNGSSEKREVRQFQFTAWP-DHGVPEHP 200 Query: 79 QIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALIEGGMKYEDAV 130 +L VK + G + VHC AG+GR + + + +K+E V Sbjct: 201 TPFLAFLRRVKTCNPPDAGPMV-VHCSAGVGRTGCFIVIDAMLERIKHEKTV 251 >6BZS-A nrPDB Length = 238 Score = 26.2 bits (56), Expect = 7.0, Method: Compositional matrix adjust. Identities = 21/78 (26%), Positives = 35/78 (44%), Gaps = 13/78 (16%) Query: 63 IHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVA----LA 118 IH + + +PP L +I GC +AV G G++ +L A L+ Sbjct: 10 IHSATFAWSQESPPC---------LHRINLTVPQGCLLAVVGPVGAGKSSLLSALLGELS 60 Query: 119 LIEGGMKYEDAVQFIRQK 136 +EG + E AV ++ Q+ Sbjct: 61 KVEGFVSIEGAVAYVPQE 78 >6D67-A nrPDB Length = 520 Score = 25.8 bits (55), Expect = 9.6, Method: Compositional matrix adjust. Identities = 13/43 (30%), Positives = 25/43 (58%), Gaps = 1/43 (2%) Query: 97 GCCIAVHCVAGLGR-APVLVALALIEGGMKYEDAVQFIRQKRR 138 G + VH AG+ R A + +A + +K ++A +F++Q+R Sbjct: 451 GGRVFVHSQAGISRSATICLAYLMRTNRVKLDEAFEFVKQRRS 493 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 5LXQ-B nrPDB 291 1e-79 1XM2-A nrPDB 290 2e-79 3RZ2-A nrPDB 280 3e-76 5K23-A nrPDB 275 6e-75 1V3A-A nrPDB 272 6e-74 5K22-A nrPDB 270 2e-73 1ZCK-A nrPDB 255 8e-69 3S4O-A nrPDB 166 5e-42 5XW4-A nrPDB 154 2e-38 5Z59-A nrPDB 147 3e-36 1OHC-A nrPDB 139 6e-34 3RO1-A nrPDB 105 1e-23 5BZX-A nrPDB 96 9e-21 2H03-A nrPDB 89 1e-18 5HDE-A nrPDB 88 1e-18 4BPC-A nrPDB 84 5e-17 1LAR-A nrPDB 83 5e-17 3M4U-A nrPDB 82 9e-17 Sequences not found previously or not previously below threshold: 3OLR-A nrPDB 76 6e-15 4ERC-A nrPDB 76 7e-15 6D3F-A nrPDB 74 5e-14 2JJD-A nrPDB 73 7e-14 1P15-A nrPDB 72 1e-13 3I36-A nrPDB 72 1e-13 2B3O-A nrPDB 70 3e-13 4AZ1-A nrPDB 69 1e-12 2CFV-A nrPDB 68 2e-12 3V0J-A nrPDB 68 2e-12 4GE6-A nrPDB 67 3e-12 2PI7-A nrPDB 67 6e-12 4HJQ-A nrPDB 66 7e-12 2GJT-A nrPDB 66 7e-12 3PS5-A nrPDB 66 7e-12 2NV5-A nrPDB 65 2e-11 2A8B-A nrPDB 64 3e-11 4BJO-A nrPDB 64 4e-11 2C46-A nrPDB 64 5e-11 2QEP-A nrPDB 63 8e-11 1RPM-A nrPDB 62 9e-11 1WCH-A nrPDB 62 9e-11 3S3F-A nrPDB 62 1e-10 2OOQ-A nrPDB 62 1e-10 2I75-A nrPDB 62 2e-10 1L8K-A nrPDB 61 2e-10 6D4D-A nrPDB 61 3e-10 2I1Y-A nrPDB 61 3e-10 1I9T-A nrPDB 60 3e-10 2C7S-A nrPDB 60 4e-10 4GFV-A nrPDB 59 8e-10 1YN9-A nrPDB 59 9e-10 5AWX-A nrPDB 59 1e-09 4H1O-A nrPDB 59 1e-09 1FPZ-A nrPDB 58 2e-09 6CMQ-A nrPDB 58 2e-09 4PVG-A nrPDB 57 3e-09 1YFO-A nrPDB 57 4e-09 5OVR-A nrPDB 57 5e-09 1YGU-A nrPDB 57 5e-09 2NLK-A nrPDB 56 6e-09 4IKC-A nrPDB 56 6e-09 4RHG-A nrPDB 56 8e-09 2BZL-A nrPDB 56 9e-09 2PBN-A nrPDB 55 1e-08 1ZC0-A nrPDB 55 1e-08 6H8S-A nrPDB 54 4e-08 2Q47-A nrPDB 50 4e-07 2G6Z-A nrPDB 48 2e-06 2R0B-A nrPDB 47 5e-06 4YR8-G nrPDB 47 6e-06 6DR7-A nrPDB 46 8e-06 3F41-A nrPDB 46 8e-06 3RGQ-A nrPDB 45 1e-05 4KYQ-A nrPDB 44 3e-05 3LJ8-A nrPDB 44 3e-05 1ZZW-A nrPDB 44 3e-05 1M3G-A nrPDB 44 4e-05 1WRM-A nrPDB 44 5e-05 4MBB-A nrPDB 44 5e-05 2OUD-A nrPDB 44 5e-05 2RF6-A nrPDB 42 1e-04 4B04-A nrPDB 42 1e-04 5GTJ-A nrPDB 42 1e-04 6N8N-Y nrPDB 42 2e-04 6I28-A nrPDB 41 2e-04 6D67-A nrPDB 41 3e-04 2ESB-A nrPDB 41 3e-04 4NX8-A nrPDB 41 3e-04 2WGP-A nrPDB 41 3e-04 6E3B-A nrPDB 41 3e-04 1G4W-R nrPDB 40 4e-04 4TVV-A nrPDB 40 4e-04 5XJV-A nrPDB 40 5e-04 1J4X-A nrPDB 40 6e-04 4JMK-A nrPDB 40 7e-04 4R30-A nrPDB 39 0.001 4RKK-A nrPDB 39 0.001 3EZZ-A nrPDB 39 0.002 1YZ4-A nrPDB 38 0.002 4Y2E-A nrPDB 37 0.003 2M3V-A nrPDB 36 0.007 3D1Q-A nrPDB 36 0.008 1MKP-A nrPDB 36 0.010 4R0S-A nrPDB 35 0.012 5NCR-A nrPDB 32 0.15 4KI9-A nrPDB 32 0.17 2OZ5-A nrPDB 32 0.19 2QFY-A nrPDB 30 0.43 4D3P-A nrPDB 30 0.58 4CBI-A nrPDB 29 1.1 4PYH-A nrPDB 29 1.4 5WX1-A nrPDB 28 1.9 5MIO-C nrPDB 28 2.7 5WSO-A nrPDB 28 2.8 2EH6-A nrPDB 27 5.0 4PNE-A nrPDB 27 6.4 1KF9-A nrPDB 26 7.6 2HFB-A nrPDB 26 9.7 >5LXQ-B nrPDB Length = 196 Score = 291 bits (744), Expect = 1e-79, Method: Composition-based stats. Identities = 173/173 (100%), Positives = 173/173 (100%) Query: 1 MARMNRPAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEK 60 MARMNRPAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEK Sbjct: 24 MARMNRPAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEK 83 Query: 61 EGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALI 120 EGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALI Sbjct: 84 EGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALI 143 Query: 121 EGGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFKDSNGHRNNCCIQ 173 EGGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFKDSNGHRNNCCIQ Sbjct: 144 EGGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFKDSNGHRNNCCIQ 196 >1XM2-A nrPDB Length = 173 Score = 290 bits (742), Expect = 2e-79, Method: Composition-based stats. Identities = 172/173 (99%), Positives = 172/173 (99%) Query: 1 MARMNRPAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEK 60 MARMNRPAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEK Sbjct: 1 MARMNRPAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEK 60 Query: 61 EGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALI 120 EGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVH VAGLGRAPVLVALALI Sbjct: 61 EGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHSVAGLGRAPVLVALALI 120 Query: 121 EGGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFKDSNGHRNNCCIQ 173 EGGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFKDSNGHRNNCCIQ Sbjct: 121 EGGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFKDSNGHRNNCCIQ 173 >3RZ2-A nrPDB Length = 189 Score = 280 bits (715), Expect = 3e-76, Method: Composition-based stats. Identities = 169/169 (100%), Positives = 169/169 (100%) Query: 1 MARMNRPAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEK 60 MARMNRPAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEK Sbjct: 21 MARMNRPAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEK 80 Query: 61 EGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALI 120 EGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALI Sbjct: 81 EGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALI 140 Query: 121 EGGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFKDSNGHRNN 169 EGGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFKDSNGHRNN Sbjct: 141 EGGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFKDSNGHRNN 189 >5K23-A nrPDB Length = 189 Score = 275 bits (704), Expect = 6e-75, Method: Composition-based stats. Identities = 149/170 (87%), Positives = 160/170 (94%), Gaps = 3/170 (1%) Query: 4 MNRPAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEKEGI 63 MNRPAPVE++Y+NMRFLITHNPTNATLNKF EELKKYGVTT+VRVC+ATYD VEKEGI Sbjct: 23 MNRPAPVEISYENMRFLITHNPTNATLNKFTEELKKYGVTTLVRVCDATYDKAPVEKEGI 82 Query: 64 HVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALIEGG 123 HVLDWPFDDGAPP NQIVDDWL+L+K KFREEPGCC+AVHCVAGLGRAPVLVALALIE G Sbjct: 83 HVLDWPFDDGAPPPNQIVDDWLNLLKTKFREEPGCCVAVHCVAGLGRAPVLVALALIECG 142 Query: 124 MKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFKDSNGHRNNCCIQ 173 MKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRF+D+NGH CC+Q Sbjct: 143 MKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFRDTNGH---CCVQ 189 >1V3A-A nrPDB Length = 173 Score = 272 bits (695), Expect = 6e-74, Method: Composition-based stats. Identities = 136/172 (79%), Positives = 152/172 (88%) Query: 1 MARMNRPAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEK 60 MARMNRPAPVEV+YK+MRFLITHNPTNATL+ FIE+LKKYG TT+VRVCE TYD T +EK Sbjct: 1 MARMNRPAPVEVSYKHMRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEK 60 Query: 61 EGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALI 120 +GI V+DWPFDDGAPP ++V+DWLSLVK KF E PG C+AVHCVAGLGRAPVLVALALI Sbjct: 61 DGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALI 120 Query: 121 EGGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFKDSNGHRNNCCI 172 E GMKYEDA+QFIRQKRRGA NSKQL YLEKYRPK RLRFKD + H+ CC+ Sbjct: 121 ESGMKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQRLRFKDPHTHKTRCCV 172 >5K22-A nrPDB Length = 183 Score = 270 bits (691), Expect = 2e-73, Method: Composition-based stats. Identities = 144/165 (87%), Positives = 155/165 (93%) Query: 2 ARMNRPAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEKE 61 + MNRPAPVE++Y+NMRFLITHNPTNATLNKF EELKKYGVTT+VRVC+ATYD VEKE Sbjct: 19 SHMNRPAPVEISYENMRFLITHNPTNATLNKFTEELKKYGVTTLVRVCDATYDKAPVEKE 78 Query: 62 GIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALIE 121 GIHVLDWPFDDGAPP NQIVDDWL+L+K KFREEPG +AVHCVAGLGRAPVLVALALIE Sbjct: 79 GIHVLDWPFDDGAPPPNQIVDDWLNLLKTKFREEPGAAVAVHCVAGLGRAPVLVALALIE 138 Query: 122 GGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFKDSNGH 166 GMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRF+D+NGH Sbjct: 139 AGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFRDTNGH 183 >1ZCK-A nrPDB Length = 154 Score = 255 bits (651), Expect = 8e-69, Method: Composition-based stats. Identities = 154/154 (100%), Positives = 154/154 (100%) Query: 7 PAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEKEGIHVL 66 PAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEKEGIHVL Sbjct: 1 PAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEKEGIHVL 60 Query: 67 DWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALIEGGMKY 126 DWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALIEGGMKY Sbjct: 61 DWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALIEGGMKY 120 Query: 127 EDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRF 160 EDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRF Sbjct: 121 EDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRF 154 >3S4O-A nrPDB Length = 167 Score = 166 bits (420), Expect = 5e-42, Method: Composition-based stats. Identities = 71/152 (46%), Positives = 97/152 (63%), Gaps = 7/152 (4%) Query: 9 PVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEKEGIHVLDW 68 P + + FLI P+ + L +I+EL+ GV +VRVC TYD TLV+ GI V W Sbjct: 15 PQKPSRVLFHFLILDAPSPSNLPTYIKELQHRGVRHLVRVCGPTYDATLVKSRGIDVHSW 74 Query: 69 PFDDGAPPSNQIVDDWLSLVKIKF---REEPGCC---IAVHCVAGLGRAPVLVALALIEG 122 PFDDGAPP+ ++D WL L+ + +E+P I VHCVAGLGRAP+LVALAL+E Sbjct: 75 PFDDGAPPTRAVLDSWLKLLDTELARQQEDPSVPPPTIGVHCVAGLGRAPILVALALVEY 134 Query: 123 G-MKYEDAVQFIRQKRRGAFNSKQLLYLEKYR 153 G + DA+ IR+KR+GA N Q+ ++ KY+ Sbjct: 135 GNVSALDAIALIREKRKGAINQTQMHWITKYK 166 >5XW4-A nrPDB Length = 415 Score = 154 bits (388), Expect = 2e-38, Method: Composition-based stats. Identities = 41/137 (29%), Positives = 59/137 (43%), Gaps = 7/137 (5%) Query: 22 THNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEKEGIHVLDWPFDDGAPPSNQIV 81 + P + LN F V +VR+ Y+ E GI LD F+DG P IV Sbjct: 248 LNQPFKSVLNFFANN----NVQLVVRLNSHLYNKKHFEDIGIQHLDLIFEDGTCPDLSIV 303 Query: 82 DDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALIEG-GMKYEDAVQFIRQKRRGA 140 +++ + + G IAVHC AGLGR L+ LI G + + F+R R G Sbjct: 304 KNFVGAAETIIKR--GGKIAVHCKAGLGRTGCLIGAHLIYTYGFTANECIGFLRFIRPGM 361 Query: 141 FNSKQLLYLEKYRPKMR 157 Q +L ++ R Sbjct: 362 VVGPQQHWLYLHQNDFR 378 >5Z59-A nrPDB Length = 147 Score = 147 bits (371), Expect = 3e-36, Method: Composition-based stats. Identities = 35/135 (25%), Positives = 64/135 (47%), Gaps = 5/135 (3%) Query: 14 YKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEKEGIHVLDWPFDDG 73 + + R + P L++ + V +V E Y EK G+ VL P D Sbjct: 7 FIDGRVAFSRMPAERELDEVARDFD--AVVVLVEDYELPYSLDEWEKRGVEVLHGPIPDF 64 Query: 74 APPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVL-VALALIEGGMKYEDAVQF 132 PS + + + L ++ + RE G + +HC+ GLGR+ + VA + G+ +A+ Sbjct: 65 TAPSVEQLLEILRWIEERVRE--GKKVLIHCMGGLGRSGTVGVAWLMYSRGLSLREALME 122 Query: 133 IRQKRRGAFNSKQLL 147 +R+KR GA +++ + Sbjct: 123 VRRKRPGAVETQEQM 137 >1OHC-A nrPDB Length = 348 Score = 139 bits (350), Expect = 6e-34, Method: Composition-based stats. Identities = 38/129 (29%), Positives = 62/129 (48%), Gaps = 6/129 (4%) Query: 31 NKFIEELKKYGVTTIVRVCEATYDTTLVEKEGIHVLDWPFDDGAPPSNQIVDDWLSLVKI 90 +I+ K + VTTI+R+ + YD G D F DG+ P++ IV ++L + Sbjct: 208 ETYIQYFKNHNVTTIIRLNKRMYDAKRFTDAGFDHHDLFFADGSTPTDAIVKEFLDIC-- 265 Query: 91 KFREEPGCCIAVHCVAGLGRAPVLVALALIEG-GMKYEDAVQFIRQKRRGAFNSKQLLYL 149 E IAVHC AGLGR L+A +++ M + + ++R R G+ Q +L Sbjct: 266 ---ENAEGAIAVHCKAGLGRTGTLIACYIMKHYRMTAAETIAWVRICRPGSVIGPQQQFL 322 Query: 150 EKYRPKMRL 158 + + L Sbjct: 323 VMKQTNLWL 331 >3RO1-A nrPDB Length = 161 Score = 105 bits (261), Expect = 1e-23, Method: Composition-based stats. Identities = 32/102 (31%), Positives = 55/102 (53%), Gaps = 7/102 (6%) Query: 50 EATYDTTLVEKEGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLG 109 + Y ++++K G+ L P DG PS+ +L+++K E+ G VHCV G+G Sbjct: 47 DKDYYLSILKKNGLQPLHIPIPDGGVPSDS---QFLTIMKWLLSEKEGN--LVHCVGGIG 101 Query: 110 RAPVLVALALI-EGGMKYEDAVQFIRQKRRGAFNS-KQLLYL 149 R ++A LI G++ E A+ +R R GA + +Q ++L Sbjct: 102 RTGTILASYLILTEGLEVESAIDEVRLVRPGAVQTYEQEMFL 143 >5BZX-A nrPDB Length = 314 Score = 95.9 bits (237), Expect = 9e-21, Method: Composition-based stats. Identities = 37/159 (23%), Positives = 64/159 (40%), Gaps = 19/159 (11%) Query: 10 VEVTYKNMRFLITHNPTNA-------TLNKFIEEL--KKYGVTTIVRVC-EATYDTTLVE 59 +++TY + P ++ + L K I +C E YDT Sbjct: 10 LDLTYIYPNIIAMGFPAERLEGVYRNNIDDVVRFLDSKHKNHYKIYNLCAERHYDTA--- 66 Query: 60 KEGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALAL 119 K V +PF+D PP +++ + + E+ A+HC AG GR V++ L Sbjct: 67 KFNCRVAQYPFEDHNPPQLELIKPFCEDLDQWLSEDDNHVAAIHCKAGKGRTGVMICAYL 126 Query: 120 IEGG--MKYEDAVQFIRQKR----RGAFNSKQLLYLEKY 152 + G +K ++A+ F + R +G Q Y+ Y Sbjct: 127 LHRGKFLKAQEALDFYGEVRTRDKKGVTIPSQRRYVYYY 165 >2H03-A nrPDB Length = 291 Score = 88.6 bits (218), Expect = 1e-18, Method: Composition-based stats. Identities = 32/142 (22%), Positives = 52/142 (36%), Gaps = 19/142 (13%) Query: 20 LITHNPTNATLNKF-IEELKKYGVTTIVRVCEATYDTTLVEKEGIHVLDWPFDDGAPPSN 78 LI + + L ++ I E K +C H WP D G P + Sbjct: 149 LILQMLSESVLPEWTIREFK---------ICGEEQLDAHRLIRHFHYTVWP-DHGVPETT 198 Query: 79 QIVDDWLSLVKIKFREEPG-CCIAVHCVAGLGRAPVLVALALIEGGMKYEDAVQFI---- 133 Q + ++ V+ PG VHC AG+GR +AL I + +D+V Sbjct: 199 QSLIQFVRTVRDYINRSPGAGPTVVHCSAGVGRTGTFIALDRILQQLDSKDSVDIYGAVH 258 Query: 134 --RQKRRGAFNSKQLLYLEKYR 153 R R + + Y+ ++ Sbjct: 259 DLRLHRVHMVQT-ECQYVYLHQ 279 >5HDE-A nrPDB Length = 307 Score = 88.2 bits (217), Expect = 1e-18, Method: Composition-based stats. Identities = 28/96 (29%), Positives = 46/96 (47%), Gaps = 11/96 (11%) Query: 63 IHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVA----LA 118 H ++WP D P S + D +SL++ K++E I +HC AG GR + A Sbjct: 198 FHYVNWP-DHDVPSSFDSILDMISLMR-KYQEHEDVPICIHCSAGCGRTGAICAIDYTWN 255 Query: 119 LIEGGMKYED-----AVQFIRQKRRGAFNSKQLLYL 149 L++ G E+ +Q +R +R A +K+ L Sbjct: 256 LLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYEL 291 >4BPC-A nrPDB Length = 582 Score = 83.6 bits (205), Expect = 5e-17, Method: Composition-based stats. Identities = 27/94 (28%), Positives = 43/94 (45%), Gaps = 10/94 (10%) Query: 61 EGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPG--CCIAVHCVAGLGRAPVLVALA 118 DWP + G P S + D++ V K +E+ G I+VHC AG+GR V + L+ Sbjct: 471 RQFQFTDWP-EQGVPKSGEGFIDFIGQVH-KTKEQFGQDGPISVHCSAGVGRTGVFITLS 528 Query: 119 LIEGGMKYEDAVQFI------RQKRRGAFNSKQL 146 ++ M+YE V R +R ++ Sbjct: 529 IVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDE 562 Score = 65.1 bits (157), Expect = 1e-11, Method: Composition-based stats. Identities = 23/94 (24%), Positives = 34/94 (36%), Gaps = 8/94 (8%) Query: 59 EKEGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALA 118 E WP D G P +L VK + G I VHC AG+GR + + Sbjct: 180 EVRQFQFTAWP-DHGVPEYPTPFLAFLRRVKTANPPDAG-PIVVHCSAGVGRTGAFIVID 237 Query: 119 LIEGGMKYEDAVQ------FIRQKRRGAFNSKQL 146 + +K E V +R +R ++ Sbjct: 238 AMLERIKPEKTVDVYGHVTLMRSQRNYMVQTEDQ 271 >1LAR-A nrPDB Length = 575 Score = 83.2 bits (204), Expect = 5e-17, Method: Composition-based stats. Identities = 27/97 (27%), Positives = 43/97 (44%), Gaps = 10/97 (10%) Query: 61 EGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPG--CCIAVHCVAGLGRAPVLVALA 118 DWP + G P + + D++ V K +E+ G I VHC AG+GR V + L+ Sbjct: 464 RQFQFTDWP-EQGVPKTGEGFIDFIGQVH-KTKEQFGQDGPITVHCSAGVGRTGVFITLS 521 Query: 119 LIEGGMKYEDAVQFI------RQKRRGAFNSKQLLYL 149 ++ M+YE V R +R ++ L Sbjct: 522 IVLERMRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQL 558 Score = 65.1 bits (157), Expect = 2e-11, Method: Composition-based stats. Identities = 23/94 (24%), Positives = 37/94 (39%), Gaps = 8/94 (8%) Query: 59 EKEGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALA 118 E + WP D G P + +L VK + G + VHC AG+GR + + Sbjct: 173 ELRQFQFMAWP-DHGVPEYPTPILAFLRRVKACNPLDAG-PMVVHCSAGVGRTGCFIVID 230 Query: 119 LIEGGMKYEDAVQF------IRQKRRGAFNSKQL 146 + MK+E V +R +R ++ Sbjct: 231 AMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQ 264 >3M4U-A nrPDB Length = 306 Score = 82.4 bits (202), Expect = 9e-17, Method: Composition-based stats. Identities = 31/92 (33%), Positives = 42/92 (45%), Gaps = 12/92 (13%) Query: 63 IHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLV----ALA 118 + + WP D G P S D+ LS++K P I VHC AG+GR L+ AL Sbjct: 192 VQYVGWP-DHGVPESAASFDELLSVIKNCVTTSP---ILVHCSAGIGRTGTLIGAYAALL 247 Query: 119 LIEGGMKYEDAVQFI----RQKRRGAFNSKQL 146 IE G+ + V I +QKR G + Sbjct: 248 HIERGILTDSTVYSIVAAMKQKRFGMVQRLEQ 279 >3OLR-A nrPDB Length = 313 Score = 76.3 bits (186), Expect = 6e-15, Method: Composition-based stats. Identities = 26/123 (21%), Positives = 52/123 (42%), Gaps = 11/123 (8%) Query: 36 ELKKYGVTTIVRVCEATYDTTLVEKEGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREE 95 E +K I+R + +++ H +WP D P S + + + V+ ++E+ Sbjct: 180 EAEKRKSDYIIRTLKVKFNSETRTIYQFHYKNWP-DHDVPSSIDPILELIWDVR-CYQED 237 Query: 96 PGCCIAVHCVAGLGRAPVLVA----LALIEGGMKYE-----DAVQFIRQKRRGAFNSKQL 146 I +H AG GR V+ A L++ G+ E ++ +R +R +++ Sbjct: 238 DSVPICIHSSAGCGRTGVICAIDYTWMLLKDGIIPENFSVFSLIREMRTQRPSLVQTQEQ 297 Query: 147 LYL 149 L Sbjct: 298 YEL 300 >4ERC-A nrPDB Length = 150 Score = 76.3 bits (186), Expect = 7e-15, Method: Composition-based stats. Identities = 30/121 (24%), Positives = 51/121 (42%), Gaps = 10/121 (8%) Query: 30 LNKFIEELKKYGVTTIVRVCEA---TYDTTLVEKEGIHVLDWPFDDGAPPSNQIVDDWLS 86 L + L GV +V + E D+ G+ + D PP+ +D ++ Sbjct: 24 LPAHYQFLLDLGVRHLVSLTERGPPHSDSCP----GLTLHRLRIPDFCPPAPDQIDRFVQ 79 Query: 87 LVKIKFREEPGCCIAVHCVAGLGRAPVLVALALI-EGGMKYEDAVQFIRQKRRGAFNSKQ 145 +V G + VHC G GR ++A L+ E G+ DA+ IR+ R G+ + + Sbjct: 80 IVDEANAR--GEAVGVHCALGFGRTGTMLACYLVKERGLAAGDAIAEIRRLRPGSIETYE 137 Query: 146 L 146 Sbjct: 138 Q 138 >6D3F-A nrPDB Length = 279 Score = 73.6 bits (179), Expect = 5e-14, Method: Composition-based stats. Identities = 28/109 (25%), Positives = 46/109 (42%), Gaps = 8/109 (7%) Query: 61 EGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALI 120 H WP + G P + + D ++ V+ + ++ I VHC AG GR +AL+ I Sbjct: 167 RQFHFHGWP-EIGIPAEGKGMIDLIAAVQKQQQQTGNHPITVHCSAGAGRTGTFIALSNI 225 Query: 121 EGGMKYE------DAVQFIRQKRRGAFNS-KQLLYLEKYRPKMRLRFKD 162 +K E AV+ +R +R + +Q + K F D Sbjct: 226 LERVKAEGLLDVFQAVKSLRLQRPHMVQTLEQYEFCYKVVQDFIDIFSD 274 >2JJD-A nrPDB Length = 599 Score = 72.8 bits (177), Expect = 7e-14, Method: Composition-based stats. Identities = 28/109 (25%), Positives = 46/109 (42%), Gaps = 8/109 (7%) Query: 61 EGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALI 120 H WP + G P + + D ++ V+ + ++ I VHC AG GR +AL+ I Sbjct: 483 RQFHFHGWP-EIGIPAEGKGMIDLIAAVQKQQQQTGNHPITVHCSAGAGRTGTFIALSNI 541 Query: 121 EGGMKYE------DAVQFIRQKRRGAFNS-KQLLYLEKYRPKMRLRFKD 162 +K E AV+ +R +R + +Q + K F D Sbjct: 542 LERVKAEGLLDVFQAVKSLRLQRPHMVQTLEQYEFCYKVVQDFIDIFSD 590 Score = 61.3 bits (147), Expect = 2e-10, Method: Composition-based stats. Identities = 26/97 (26%), Positives = 38/97 (39%), Gaps = 9/97 (9%) Query: 63 IHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALIEG 122 +H WP D G P + + +L VK G I VHC AG+GR + + + Sbjct: 191 LHFTSWP-DFGVPFTPIGMLKFLKKVKTLNPVHAG-PIVVHCSAGVGRTGTFIVIDAMMA 248 Query: 123 GMKYEDAVQF------IRQKRRGAFNSKQLLYLEKYR 153 M E V IR +R + + Y Y+ Sbjct: 249 MMHAEQKVDVFEFVSRIRNQRPQMVQT-DMQYTFIYQ 284 >1P15-A nrPDB Length = 253 Score = 72.4 bits (176), Expect = 1e-13, Method: Composition-based stats. Identities = 29/135 (21%), Positives = 55/135 (40%), Gaps = 10/135 (7%) Query: 35 EELKKYGVTTIVRVCEATYDTTLVEKEGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFRE 94 EE + Y V ++ + + + H WP + G P + + + ++ V+ + ++ Sbjct: 117 EECESYTVRDLLVTNTRENKSRQIRQ--FHFHGWP-EVGIPSDGKGMINIIAAVQKQQQQ 173 Query: 95 EPGCCIAVHCVAGLGRAPVLVALALIEGGMKYE------DAVQFIRQKRRGAFNS-KQLL 147 I VHC AG GR AL+ + +K E V+ +R +R + +Q Sbjct: 174 SGNHPITVHCSAGAGRTGTFCALSTVLERVKAEGILDVFQTVKSLRLQRPHMVQTLEQYE 233 Query: 148 YLEKYRPKMRLRFKD 162 + K + F D Sbjct: 234 FCYKVVQEYIDAFSD 248 >3I36-A nrPDB Length = 342 Score = 72.0 bits (175), Expect = 1e-13, Method: Composition-based stats. Identities = 22/93 (23%), Positives = 39/93 (41%), Gaps = 8/93 (8%) Query: 61 EGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFRE-EPGCCIAVHCVAGLGRAPVLVALAL 119 H WP D G P + ++ ++ LV+ ++ P I VHC AG+GR +A+ Sbjct: 201 RQFHFTSWP-DHGVPDTTDLLINFRYLVRDYMKQIPPESPILVHCSAGVGRTGTFIAIDR 259 Query: 120 IEGGMKYEDAVQFI------RQKRRGAFNSKQL 146 + ++ E+ V R R ++ Sbjct: 260 LIYQIENENTVDVYGIVYDLRMHRPLMVQTEDQ 292 >2B3O-A nrPDB Length = 532 Score = 70.5 bits (171), Expect = 3e-13, Method: Composition-based stats. Identities = 22/99 (22%), Positives = 40/99 (40%), Gaps = 12/99 (12%) Query: 63 IHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEP-GCCIAVHCVAGLGRAPVLVALALIE 121 L WP D G P V +L + + P I VHC AG+GR ++ + ++ Sbjct: 412 YQYLSWP-DHGVPSEPGGVLSFLDQINQRQESLPHAGPIIVHCSAGIGRTGTIIVIDMLM 470 Query: 122 GGMKYED---------AVQFIRQKRRGAFNSK-QLLYLE 150 + + +Q +R +R G ++ Q ++ Sbjct: 471 ENISTKGLDCDIDIQKTIQMVRAQRSGMVQTEAQYKFIY 509 >4AZ1-A nrPDB Length = 302 Score = 68.6 bits (166), Expect = 1e-12, Method: Composition-based stats. Identities = 26/95 (27%), Positives = 41/95 (43%), Gaps = 12/95 (12%) Query: 63 IHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLV----ALA 118 + WP D G P S ++ L+ VK + VHC AG+GR L+ AL Sbjct: 189 VQYTGWP-DHGIPQSATSLEALLTNVKNSPTT---VPVVVHCSAGIGRTGTLIGAYAALT 244 Query: 119 LIEGGMKYE----DAVQFIRQKRRGAFNSKQLLYL 149 +E G + D V +R++R G + ++ Sbjct: 245 HLERGTLTDTTVYDVVSAMRRQRFGMVQRMEQYFV 279 >2CFV-A nrPDB Length = 316 Score = 68.2 bits (165), Expect = 2e-12, Method: Composition-based stats. Identities = 21/93 (22%), Positives = 38/93 (40%), Gaps = 8/93 (8%) Query: 61 EGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEP-GCCIAVHCVAGLGRAPVLVALAL 119 H P D G P + ++ ++ LV+ ++ P I VHC AG+GR +A+ Sbjct: 201 RQFHFTSAP-DHGVPDTTDLLINFRYLVRDYMKQSPPESPILVHCSAGVGRTGTFIAIDR 259 Query: 120 IEGGMKYEDAVQFI------RQKRRGAFNSKQL 146 + ++ E+ V R R ++ Sbjct: 260 LIYQIENENTVDVYGIVYDLRMHRPLMVQTEDQ 292 >3V0J-A nrPDB Length = 334 Score = 67.8 bits (164), Expect = 2e-12, Method: Composition-based stats. Identities = 32/133 (24%), Positives = 53/133 (39%), Gaps = 8/133 (6%) Query: 16 NMRFLITHNPTNATLNKFIEELKKYGVTTIVRVC-EATYDTTLVEKEGIHVLDWPFDDGA 74 + R + NP F + K I +C E YD T + HV DD Sbjct: 42 SGRQSLFRNPIGEVSRFF--KTKHPDKFRIYNLCSERGYDETKFDN---HVYRVMIDDHN 96 Query: 75 PPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALIEGGM--KYEDAVQF 132 P+ + ++ K+ +P IA+H G GR LV+ L+E G ++A+++ Sbjct: 97 VPTLVDLLKFIDDAKVWMTSDPDHVIAIHSKGGKGRTGTLVSSWLLEDGKFDTAKEALEY 156 Query: 133 IRQKRRGAFNSKQ 145 +R F + Sbjct: 157 FGSRRTDVFQGVE 169 >4GE6-A nrPDB Length = 314 Score = 67.4 bits (163), Expect = 3e-12, Method: Composition-based stats. Identities = 30/137 (21%), Positives = 52/137 (37%), Gaps = 27/137 (19%) Query: 34 IEELKKYGVTTIVRVCEATYDTTLVEKEG---IHVLDWPFDDGAPPSNQIVDDWLSLVKI 90 +E + Y TT+ ++T +K L WP D G P S + D+L +V+ Sbjct: 161 VENMNHYKKTTL-----EIHNTEERQKRQVTHFQFLSWP-DYGVPSSAASLIDFLRVVRN 214 Query: 91 KFR------------EEPGCCIAVHCVAGLGRAPVLVALALIEGGMK------YEDAVQF 132 + + P I VHC AG+GR +L + ++ V Sbjct: 215 QQSLAVSNMGARSKGQCPEPPIVVHCSAGIGRTGTFCSLDICLAQLEELGTLNVFQTVSR 274 Query: 133 IRQKRRGAFNSKQLLYL 149 +R +R + + + Y Sbjct: 275 MRTQRAFSIQTPEQYYF 291 >2PI7-A nrPDB Length = 312 Score = 66.6 bits (161), Expect = 6e-12, Method: Composition-based stats. Identities = 23/117 (19%), Positives = 51/117 (43%), Gaps = 11/117 (9%) Query: 45 IVRVCEATYDTTLVEKEGIHVLDWPFDDGAPPSN--QIVDDWLSLVKIKFREEPGCCIAV 102 + R +Y + + + WP D G P +N + + ++ +V+ K + G + + Sbjct: 173 VYRNFRISYADEVQDVMHFNYTAWP-DHGVPTANAAESILQFVQMVRQKSVKSKG-PMII 230 Query: 103 HCVAGLGRAPVLVALALIEGGMKYEDAVQF------IRQKRRGAFNSKQLLYLEKYR 153 HC AG+GR +AL + ++ + V +R R +++ Y+ ++ Sbjct: 231 HCSAGVGRTGTFIALDWLLQHIRDHEFVDILGLVSDMRSYRMSMVQTEEQ-YIFIHQ 286 >4HJQ-A nrPDB Length = 308 Score = 66.3 bits (160), Expect = 7e-12, Method: Composition-based stats. Identities = 21/99 (21%), Positives = 39/99 (39%), Gaps = 12/99 (12%) Query: 63 IHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEP-GCCIAVHCVAGLGRAPVLVALALIE 121 L WP D G P V +L + + P I VH AG+GR ++ + ++ Sbjct: 192 YQYLSWP-DHGVPSEPGGVLSFLDQINQRQESLPHAGPIIVHSSAGIGRTGTIIVIDMLM 250 Query: 122 GGMKYED---------AVQFIRQKRRGAFNSK-QLLYLE 150 + + +Q +R +R G ++ Q ++ Sbjct: 251 ENISTKGLDCDIDIQKTIQMVRAQRSGMVQTEAQYKFIY 289 >2GJT-A nrPDB Length = 295 Score = 66.3 bits (160), Expect = 7e-12, Method: Composition-based stats. Identities = 20/99 (20%), Positives = 45/99 (45%), Gaps = 11/99 (11%) Query: 63 IHVLDWPFDDGAPPSN--QIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALI 120 + WP D G P +N + + ++ +V+ + + G + +HC AG+GR +AL + Sbjct: 182 FNYTAWP-DHGVPTANAAESILQFVHMVRQQATKSKG-PMIIHCSAGVGRTGTFIALDRL 239 Query: 121 EGGMKYEDAVQ------FIRQKRRGAFNSKQLLYLEKYR 153 ++ + V +R R +++ Y+ ++ Sbjct: 240 LQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQ-YIFIHQ 277 >3PS5-A nrPDB Length = 595 Score = 66.3 bits (160), Expect = 7e-12, Method: Composition-based stats. Identities = 21/99 (21%), Positives = 39/99 (39%), Gaps = 12/99 (12%) Query: 63 IHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEP-GCCIAVHCVAGLGRAPVLVALALIE 121 L WP D G P V +L + + P I VH AG+GR ++ + ++ Sbjct: 412 YQYLSWP-DHGVPSEPGGVLSFLDQINQRQESLPHAGPIIVHSSAGIGRTGTIIVIDMLM 470 Query: 122 GGMKYED---------AVQFIRQKRRGAFNSK-QLLYLE 150 + + +Q +R +R G ++ Q ++ Sbjct: 471 ENISTKGLDCDIDIQKTIQMVRAQRSGMVQTEAQYKFIY 509 >2NV5-A nrPDB Length = 299 Score = 65.1 bits (157), Expect = 2e-11, Method: Composition-based stats. Identities = 23/100 (23%), Positives = 38/100 (38%), Gaps = 9/100 (9%) Query: 59 EKEGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALA 118 E WP D G P +L VK + G + VHC AG+GR + + Sbjct: 182 EVRQFQFTAWP-DHGVPEHPTPFLAFLRRVKTCNPPDAG-PMVVHCSAGVGRTGCFIVID 239 Query: 119 LIEGGMKYEDAVQF------IRQKRRGAFNSKQLLYLEKY 152 + +K+E V +R +R ++ Y+ + Sbjct: 240 AMLERIKHEKTVDIYGHVTLMRAQRNYMVQTEDQ-YIFIH 278 >2A8B-A nrPDB Length = 283 Score = 63.9 bits (154), Expect = 3e-11, Method: Composition-based stats. Identities = 28/116 (24%), Positives = 44/116 (37%), Gaps = 16/116 (13%) Query: 46 VRVCEATYDTTLVEKEGIH--------VLDWPFDDGAPPSNQIVDD-WLSLVKIKFREEP 96 V C+ LV K+G H WP D P S Q + L + + + + Sbjct: 150 VNECDNYTIRNLVLKQGSHTQHVKHYWYTSWP-DHKTPDSAQPLLQLMLDVEEDRLASQG 208 Query: 97 GCCIAVHCVAGLGRAPVLVALALIEGGMKYEDAVQ------FIRQKRRGAFNSKQL 146 + VHC AG+GR +A ++ +K E V +R R G + + Sbjct: 209 RGPVVVHCSAGIGRTGCFIATSIGCQQLKEEGVVDALSIVCQLRMDRGGMVQTSEQ 264 >4BJO-A nrPDB Length = 338 Score = 63.6 bits (153), Expect = 4e-11, Method: Composition-based stats. Identities = 32/132 (24%), Positives = 48/132 (36%), Gaps = 12/132 (9%) Query: 26 TNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEKEGIHVLDWPFDDGAPPSNQIVDDWL 85 TN L E++K Y + + T T E H WP D G P S ++L Sbjct: 155 TNLKLTLISEDIKSYYTVRQLELENLTTQETR-EILHFHYTTWP-DFGVPESPASFLNFL 212 Query: 86 SLVKIKFREEPG-CCIAVHCVAGLGRAPVLV----ALALIEGGMKYED-----AVQFIRQ 135 V+ P + VHC AG+GR+ L L++ + +R+ Sbjct: 213 FKVRESGSLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLEMRK 272 Query: 136 KRRGAFNSKQLL 147 R G + L Sbjct: 273 FRMGLIQTADQL 284 >2C46-A nrPDB Length = 241 Score = 63.6 bits (153), Expect = 5e-11, Method: Composition-based stats. Identities = 30/115 (26%), Positives = 47/115 (40%), Gaps = 3/115 (2%) Query: 27 NATLNKFIEELK-KYGVTTIVRVCEATYDTTLVEKEGIHVLDWPFD-DGAPPSNQIVDDW 84 + L+ +++ LK K G+ + YD +EKEGI + G P+ + + + Sbjct: 69 PSMLSNYLKSLKVKMGLLVDLTNTSRFYDRNDIEKEGIKYIKLQCKGHGECPTTENTETF 128 Query: 85 LSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALIEG-GMKYEDAVQFIRQKRR 138 + L + P I VHC G R L+ L+E E AV Q R Sbjct: 129 IRLCERFNERNPPELIGVHCTHGFNRTGFLICAFLVEKMDWSIEAAVATFAQARP 183 >2QEP-A nrPDB Length = 304 Score = 62.8 bits (151), Expect = 8e-11, Method: Composition-based stats. Identities = 24/91 (26%), Positives = 40/91 (43%), Gaps = 9/91 (9%) Query: 63 IHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALIEG 122 H L W +D G P S++ + D+ V +R C I VHC G GR+ V + ++ Sbjct: 193 FHFLSW-YDRGVPSSSRSLLDFRRKVNKCYR-GRSCPIIVHCSDGAGRSGTYVLIDMVLN 250 Query: 123 GM-------KYEDAVQFIRQKRRGAFNSKQL 146 M ++ +R +R G +K+ Sbjct: 251 KMAKGAKEIDIAATLEHLRDQRPGMVQTKEQ 281 >1RPM-A nrPDB Length = 278 Score = 62.4 bits (150), Expect = 9e-11, Method: Composition-based stats. Identities = 22/94 (23%), Positives = 36/94 (38%), Gaps = 8/94 (8%) Query: 59 EKEGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALA 118 E H WP D G P + ++ VK K G + VHC AG GR + + Sbjct: 174 EIRQFHFTGWP-DHGVPYHATGLLGFVRQVKSKSPPSAG-PLVVHCSAGAGRTGCFIVID 231 Query: 119 LIEGGMKYEDAVQ------FIRQKRRGAFNSKQL 146 ++ + E V +R +R +++ Sbjct: 232 IMLDMAEREGVVDIYNCVRELRSRRVNMVQTEEQ 265 >1WCH-A nrPDB Length = 315 Score = 62.4 bits (150), Expect = 9e-11, Method: Composition-based stats. Identities = 22/97 (22%), Positives = 42/97 (43%), Gaps = 11/97 (11%) Query: 63 IHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALIEG 122 ++ WP D P + ++S ++ R I HC AG+GR+ L+ + ++ G Sbjct: 209 LNFTAWP-DHDTPSQPDDLLTFISYMRHIHR---SGPIITHCSAGIGRSGTLICIDVVLG 264 Query: 123 ------GMKYEDAVQFIRQKRRGAFNSKQLLYLEKYR 153 D V+ +R +R G ++ Y+ Y+ Sbjct: 265 LISQDLDFDISDLVRCMRLQRHGMVQTEDQ-YIFCYQ 300 >3S3F-A nrPDB Length = 307 Score = 62.4 bits (150), Expect = 1e-10, Method: Composition-based stats. Identities = 23/99 (23%), Positives = 40/99 (40%), Gaps = 9/99 (9%) Query: 61 EGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALI 120 H WP D G P Q + ++ + + I VHC AG+GR+ + L I Sbjct: 201 RHFHFTTWP-DFGVPNPPQTLVRFVRAFRDRIG-AEQRPIVVHCSAGVGRSGTFITLDRI 258 Query: 121 EGGMKYEDAVQF------IRQKRRGAFNSKQLLYLEKYR 153 + D V +R++R ++Q Y+ ++ Sbjct: 259 LQQINTSDYVDIFGIVYAMRKERVWMVQTEQQ-YICIHQ 296 >2OOQ-A nrPDB Length = 286 Score = 62.0 bits (149), Expect = 1e-10, Method: Composition-based stats. Identities = 21/90 (23%), Positives = 33/90 (36%), Gaps = 8/90 (8%) Query: 63 IHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALIEG 122 H WP D G P + ++ VK I VHC AG GR +A+ + Sbjct: 180 FHFTSWP-DHGVPCYATGLLGFVRQVK-FLNPPEAGPIVVHCSAGAGRTGCFIAIDTMLD 237 Query: 123 GMKYEDAVQ------FIRQKRRGAFNSKQL 146 + E V +R +R +++ Sbjct: 238 MAENEGVVDIFNCVRELRAQRVNLVQTEEQ 267 >2I75-A nrPDB Length = 320 Score = 61.6 bits (148), Expect = 2e-10, Method: Composition-based stats. Identities = 27/90 (30%), Positives = 41/90 (45%), Gaps = 8/90 (8%) Query: 63 IHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLV----ALA 118 I + WP D G P + D++ V+ K R + VHC AG+GR VL+ A+ Sbjct: 205 IQYIAWP-DHGVPDDSSDFLDFVCHVRNK-RAGKEEPVVVHCSAGIGRTGVLITMETAMC 262 Query: 119 LIEGG--MKYEDAVQFIRQKRRGAFNSKQL 146 LIE + D V+ +R +R + Sbjct: 263 LIECNQPVYPLDIVRTMRDQRAMMIQTPSQ 292 >1L8K-A nrPDB Length = 314 Score = 60.9 bits (146), Expect = 2e-10, Method: Composition-based stats. Identities = 28/120 (23%), Positives = 47/120 (39%), Gaps = 9/120 (7%) Query: 35 EELKKYGVTTIVRVCEATYDTTLVEKEGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFRE 94 E++K Y ++++ T H WP D G P S ++L V+ Sbjct: 148 EDVKSYYTVHLLQLENINSGETRTISH-FHYTTWP-DFGVPESPASFLNFLFKVRESGSL 205 Query: 95 EPG-CCIAVHCVAGLGRAPVL----VALALIEGG--MKYEDAVQFIRQKRRGAFNSKQLL 147 P +HC AG+GR+ L L+E G + + + +R+ R G + L Sbjct: 206 NPDHGPAVIHCSAGIGRSGTFSLVDTCLVLMEKGDDINIKQVLLNMRKYRMGLIQTPDQL 265 >6D4D-A nrPDB Length = 292 Score = 60.9 bits (146), Expect = 3e-10, Method: Composition-based stats. Identities = 26/97 (26%), Positives = 38/97 (39%), Gaps = 9/97 (9%) Query: 63 IHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALIEG 122 +H WP D G P + + +L VK G I VHC AG+GR + + + Sbjct: 190 LHFTSWP-DFGVPFTPIGMLKFLKKVKTLNPVHAG-PIVVHCSAGVGRTGTFIVIDAMMA 247 Query: 123 GMKYEDAVQF------IRQKRRGAFNSKQLLYLEKYR 153 M E V IR +R + + Y Y+ Sbjct: 248 MMHAEQKVDVFEFVSRIRNQRPQMVQT-DMQYTFIYQ 283 >2I1Y-A nrPDB Length = 301 Score = 60.9 bits (146), Expect = 3e-10, Method: Composition-based stats. Identities = 24/91 (26%), Positives = 37/91 (40%), Gaps = 9/91 (9%) Query: 63 IHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALIEG 122 H L WP + G P S + + D+ V +R C I VHC G GR + + ++ Sbjct: 192 FHFLSWPAE-GTPASTRPLLDFRRKVNKCYR-GRSCPIIVHCSDGAGRTGTYILIDMVLN 249 Query: 123 GM-------KYEDAVQFIRQKRRGAFNSKQL 146 M ++ +R +R G SK Sbjct: 250 RMAKGVKEIDIAATLEHVRDQRPGLVRSKDQ 280 >1I9T-A nrPDB Length = 210 Score = 60.5 bits (145), Expect = 3e-10, Method: Composition-based stats. Identities = 29/115 (25%), Positives = 46/115 (40%), Gaps = 3/115 (2%) Query: 27 NATLNKFIEELK-KYGVTTIVRVCEATYDTTLVEKEGIHVLDWPFD-DGAPPSNQIVDDW 84 + L+ +++ LK K + + YD +EKEGI + G P+ + + + Sbjct: 47 PSMLSNYLKSLKVKMSLLVDLTNTSRFYDRNDIEKEGIKYIKLQCKGHGECPTTENTETF 106 Query: 85 LSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALIEG-GMKYEDAVQFIRQKRR 138 + L + P I VHC G R L+ L+E E AV Q R Sbjct: 107 IRLCERFNERSPPELIGVHCTHGFNRTGFLICAFLVEKMDWSIEAAVATFAQARP 161 >2C7S-A nrPDB Length = 313 Score = 60.1 bits (144), Expect = 4e-10, Method: Composition-based stats. Identities = 22/96 (22%), Positives = 37/96 (38%), Gaps = 9/96 (9%) Query: 63 IHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALIEG 122 H WP D G P + ++ VK+ G I VHC AG GR + + ++ Sbjct: 202 FHFTGWP-DHGVPYHATGLLSFIRRVKLSNPPSAG-PIVVHCSAGAGRTGCYIVIDIMLD 259 Query: 123 GMKYEDAVQFI------RQKRRGAFNSKQLLYLEKY 152 + E V R +R +++ Y+ + Sbjct: 260 MAEREGVVDIYNCVKALRSRRINMVQTEEQ-YIFIH 294 >4GFV-A nrPDB Length = 297 Score = 59.3 bits (142), Expect = 8e-10, Method: Composition-based stats. Identities = 24/123 (19%), Positives = 45/123 (36%), Gaps = 12/123 (9%) Query: 38 KKYGVTTIVRVCEATYDTTLVEKEGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPG 97 K ++R + T+ + + WP D G P S + + + P Sbjct: 162 KWLNEDIMLRTLKVTFQKESRSVYQLQYMSWP-DRGVPSSPDHMLAMVEEARRLQGSGPE 220 Query: 98 CCIAVHCVAGLGRAPVLVALALIEGGMKYE---------DAVQFIRQKRRGAFNSKQLL- 147 + VH AG GR VL + + + + D V +R++R A +++ Sbjct: 221 -PLCVHSSAGCGRTGVLCTVDYVRQLLLTQMIPPDFSLFDVVLKMRKQRPAAVQTEEQYR 279 Query: 148 YLE 150 +L Sbjct: 280 FLY 282 >1YN9-A nrPDB Length = 169 Score = 59.3 bits (142), Expect = 9e-10, Method: Composition-based stats. Identities = 20/86 (23%), Positives = 35/86 (40%), Gaps = 1/86 (1%) Query: 53 YDTTLVEKEGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAP 112 YD + G+ P IV +++ VK + PG + VHC G+ R Sbjct: 69 YDGVHFLRAGLLYKKIQVPGQTLPPESIVQEFIDTVKEFTEKCPGMLVGVHCTHGINRTG 128 Query: 113 VLVALALIEG-GMKYEDAVQFIRQKR 137 +V L+ G+ ++A+ + R Sbjct: 129 YMVCRYLMHTLGIAPQEAIDRFEKAR 154 >5AWX-A nrPDB Length = 298 Score = 58.9 bits (141), Expect = 1e-09, Method: Composition-based stats. Identities = 20/90 (22%), Positives = 35/90 (38%), Gaps = 8/90 (8%) Query: 63 IHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALIEG 122 H WP D G P + V ++ + + VHC AG+GR + L + Sbjct: 192 YHYTQWP-DMGVPEYSLPVLTFVRKA-AYAKRHAVGPVVVHCSAGVGRTGTYIVLDSMLQ 249 Query: 123 GMKYEDAVQF------IRQKRRGAFNSKQL 146 +++E V IR +R +++ Sbjct: 250 QIQHEGTVNIFGFLKHIRSQRNYLVQTEEQ 279 >4H1O-A nrPDB Length = 560 Score = 58.6 bits (140), Expect = 1e-09, Method: Composition-based stats. Identities = 34/141 (24%), Positives = 55/141 (39%), Gaps = 29/141 (20%) Query: 37 LKKYGVTTIVRVCE---ATYDTTLVE--KEG----------IHVLDWPFDDGAPPSNQIV 81 LK+YGV + V E Y ++ K G H WP D G P V Sbjct: 398 LKEYGVMRVRNVKESAAHDYTLRELKLSKVGQGNTERTVWQYHFRTWP-DHGVPSDPGGV 456 Query: 82 DDWLSLVKIKFREE--PGCCIAVHCVAGLGRAPVLVALAL---------IEGGMKYEDAV 130 D+L V K +E + VHC AG+GR + + + ++ + + Sbjct: 457 LDFLEEVHHK-QESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTI 515 Query: 131 QFIRQKRRGAFNSK-QLLYLE 150 Q +R +R G ++ Q ++ Sbjct: 516 QMVRSQRSGMVQTEAQYRFIY 536 >1FPZ-A nrPDB Length = 212 Score = 58.2 bits (139), Expect = 2e-09, Method: Composition-based stats. Identities = 37/153 (24%), Positives = 58/153 (37%), Gaps = 16/153 (10%) Query: 27 NATLNKFIEELKKYGVTTIVRVCEA--------TYDTTLVEKEGIHVLDWPFDDGAPPSN 78 + K EELK G+ I C L ++ GI P DG P Sbjct: 57 RRNVQKDTEELKSCGIQDIFVFCTRGELSKYRVPNLLDLYQQCGIITHHHPIADGGTPDI 116 Query: 79 QIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALIE--GGMKYEDAVQFIRQK 136 + + + + +H GLGR+ ++ A L+ + E A+ +R Sbjct: 117 ASCCEIMEELTTCLKNY--RKTLIHSYGGLGRSCLVAACLLLYLSDTISPEQAIDSLRDL 174 Query: 137 R-RGAFNS-KQLLYLEKYRPKM--RLRFKDSNG 165 R GA + KQ YL ++R K+ L +DS Sbjct: 175 RGSGAIQTIKQYNYLHEFRDKLAAHLSSRDSQS 207 >6CMQ-A nrPDB Length = 427 Score = 58.2 bits (139), Expect = 2e-09, Method: Composition-based stats. Identities = 34/141 (24%), Positives = 55/141 (39%), Gaps = 29/141 (20%) Query: 37 LKKYGVTTIVRVCE---ATYDTTLVE--KEG----------IHVLDWPFDDGAPPSNQIV 81 LK+YGV + V E Y ++ K G H WP D G P V Sbjct: 275 LKEYGVMRVRNVKESAAHDYTLRELKLSKVGQGNTERTVWQYHFRTWP-DHGVPSDPGGV 333 Query: 82 DDWLSLVKIKFREE--PGCCIAVHCVAGLGRAPVLVALAL---------IEGGMKYEDAV 130 D+L V K +E + VHC AG+GR + + + ++ + + Sbjct: 334 LDFLEEVHHK-QESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTI 392 Query: 131 QFIRQKRRGAFNSK-QLLYLE 150 Q +R +R G ++ Q ++ Sbjct: 393 QMVRSQRSGMVQTEAQYRFIY 413 >4PVG-A nrPDB Length = 298 Score = 57.4 bits (137), Expect = 3e-09, Method: Composition-based stats. Identities = 24/100 (24%), Positives = 41/100 (41%), Gaps = 14/100 (14%) Query: 63 IHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREE--PGCCIAVHCVAGLGRAPVLVALAL- 119 H WP D G P V D+L V K +E + VHC AG+GR + + + Sbjct: 180 YHFRTWP-DHGVPSDPGGVLDFLEEVHHK-QESIMDAGPVVVHCSAGIGRTGTFIVIDIL 237 Query: 120 --------IEGGMKYEDAVQFIRQKRRGAFNSK-QLLYLE 150 ++ + +Q +R +R G ++ Q ++ Sbjct: 238 IDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIY 277 >1YFO-A nrPDB Length = 302 Score = 57.0 bits (136), Expect = 4e-09, Method: Composition-based stats. Identities = 27/97 (27%), Positives = 39/97 (40%), Gaps = 9/97 (9%) Query: 63 IHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALIEG 122 H WP D G P + + +L VK + G I VHC AG+GR V + + Sbjct: 193 FHFTSWP-DFGVPFTPIGMLKFLKKVKACNPQYAGA-IVVHCSAGVGRTGTFVVIDAMLD 250 Query: 123 GMKYEDAVQF------IRQKRRGAFNSKQLLYLEKYR 153 M E V IR +R + + Y+ Y+ Sbjct: 251 MMHSERKVDVYGFVSRIRAQRCQMVQT-DMQYVFIYQ 286 >5OVR-A nrPDB Length = 305 Score = 56.6 bits (135), Expect = 5e-09, Method: Composition-based stats. Identities = 24/103 (23%), Positives = 41/103 (39%), Gaps = 12/103 (11%) Query: 55 TTLVEKEGIHV---LDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCC--IAVHCVAGLG 109 + E+ G+ WP D P + + V+ ++E C I VHC AG+G Sbjct: 185 KSGTEERGLKHYWFTSWP-DQKTPDRAPPLLHLVREVEEAAQQEGPHCAPIIVHCSAGIG 243 Query: 110 RAPVLVALALIEGGMKYEDAVQF------IRQKRRGAFNSKQL 146 R +A ++ ++ E V +RQ R G + + Sbjct: 244 RTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQTCEQ 286 >1YGU-A nrPDB Length = 610 Score = 56.6 bits (135), Expect = 5e-09, Method: Composition-based stats. Identities = 21/93 (22%), Positives = 33/93 (35%), Gaps = 8/93 (8%) Query: 63 IHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALIEG 122 I WP D G P ++ V F I VH AG+GR + + + Sbjct: 191 IQFTSWP-DHGVPEDPHLLLKLRRRV-NAFSNFFSGPIVVHSSAGVGRTGTYIGIDAMLE 248 Query: 123 GMKYEDAVQFI------RQKRRGAFNSKQLLYL 149 G++ E+ V R++R + L Sbjct: 249 GLEAENKVDVYGYVVKLRRQRCLMVQVEAQYIL 281 Score = 43.1 bits (100), Expect = 5e-05, Method: Composition-based stats. Identities = 17/104 (16%), Positives = 36/104 (34%), Gaps = 17/104 (16%) Query: 63 IHVLDWPFDDGAPPSNQIVDDWLSLVKIKF---------REEPGCCIAVHCVAGLGRAPV 113 +W + P + + + +VK K + + +HC G + + Sbjct: 497 YQYTNWSVEQ-LPAEPKELISMIQVVKQKLPQKNSSEGNKHHKSTPLLIHCRDGSQQTGI 555 Query: 114 LVALALIEGGMKYEDAVQFI------RQKRRGAFNS-KQLLYLE 150 AL + + E+ V R+ R G ++ +Q +L Sbjct: 556 FCALLNLLESAETEEVVDIFQVVKALRKARLGMVSTFEQYQFLY 599 >2NLK-A nrPDB Length = 627 Score = 56.2 bits (134), Expect = 6e-09, Method: Composition-based stats. Identities = 21/96 (21%), Positives = 36/96 (37%), Gaps = 9/96 (9%) Query: 63 IHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALIEG 122 H WP D G P V ++ R + VHC AG+GR + + + Sbjct: 196 YHYTQWP-DMGVPEYALPVLTFVRR-SSAARMPETGPVLVHCSAGVGRTGTYIVIDSMLQ 253 Query: 123 GMKYEDAVQF------IRQKRRGAFNSKQLLYLEKY 152 +K + V IR +R +++ Y+ + Sbjct: 254 QIKDKSTVNVLGFLKHIRTQRNYLVQTEEQ-YIFIH 288 >4IKC-A nrPDB Length = 281 Score = 56.2 bits (134), Expect = 6e-09, Method: Composition-based stats. Identities = 21/99 (21%), Positives = 40/99 (40%), Gaps = 9/99 (9%) Query: 61 EGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALI 120 + WP + G P ++ + ++ LV+ R + VH AG+GR V +AL + Sbjct: 180 RQCNFTAWP-EHGVPENSAPLIHFVKLVRAS-RAHDTTPMIVHSSAGVGRTGVFIALDHL 237 Query: 121 EGGMKYEDAVQ------FIRQKRRGAFNSKQLLYLEKYR 153 + D V +R +R + Y+ ++ Sbjct: 238 TQHINDHDFVDIYGLVAELRSERMCMVQNLAQ-YIFLHQ 275 >4RHG-A nrPDB Length = 306 Score = 55.9 bits (133), Expect = 8e-09, Method: Composition-based stats. Identities = 21/90 (23%), Positives = 38/90 (42%), Gaps = 9/90 (10%) Query: 63 IHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLV----ALA 118 + + WP + G P + ++++ V+ + VH AG+GR VLV A+ Sbjct: 201 LQYVAWP-EHGVPDDSSDFLEFVNYVRSL--RVDSEPVLVHSSAGIGRTGVLVTMETAMC 257 Query: 119 LIEGGMK--YEDAVQFIRQKRRGAFNSKQL 146 L E + D V+ +R +R + Sbjct: 258 LTERNLPIYPLDIVRKMRDQRAMMVQTSSQ 287 >2BZL-A nrPDB Length = 325 Score = 55.9 bits (133), Expect = 9e-09, Method: Composition-based stats. Identities = 25/107 (23%), Positives = 45/107 (42%), Gaps = 21/107 (19%) Query: 63 IHVLDWPFDDGAPPSNQIVDDWL-----------SLVKIKFREEPGCCIAVHCVAGLGRA 111 + DWP D G P Q +L S+++ P I VHC AG+GR Sbjct: 210 LQYTDWP-DHGCPEDVQGFLSYLEEIQSVRRHTNSMLEGTKNRHP--PIVVHCSAGVGRT 266 Query: 112 PVLVALALIEGGMKYEDAVQ------FIRQKRRGAFNS-KQLLYLEK 151 VL+ L+ +++ + V+ +R++R + Q ++ + Sbjct: 267 GVLILSELMIYCLEHNEKVEVPMMLRLLREQRMFMIQTIAQYKFVYQ 313 >2PBN-A nrPDB Length = 313 Score = 55.5 bits (132), Expect = 1e-08, Method: Composition-based stats. Identities = 21/96 (21%), Positives = 36/96 (37%), Gaps = 9/96 (9%) Query: 63 IHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALIEG 122 H WP D G P V ++ R + VHC AG+GR + + + Sbjct: 204 YHYTQWP-DMGVPEYALPVLTFVRR-SSAARMPETGPVLVHCSAGVGRTGTYIVIDSMLQ 261 Query: 123 GMKYEDAVQF------IRQKRRGAFNSKQLLYLEKY 152 +K + V IR +R +++ Y+ + Sbjct: 262 QIKDKSTVNVLGFLKHIRTQRNYLVQTEEQ-YIFIH 296 >1ZC0-A nrPDB Length = 309 Score = 55.1 bits (131), Expect = 1e-08, Method: Composition-based stats. Identities = 26/109 (23%), Positives = 39/109 (35%), Gaps = 10/109 (9%) Query: 46 VRVCEATYDTTLVEKEGIHVLDWPFDDGAPPSNQIVDDWLSLVKI--KFREEPGCCIAVH 103 VR Y + I WP D P S + ++ V+ + PG I VH Sbjct: 182 VRQLTIQYQEERRSVKHILFSAWP-DHQTPESAGPLLRLVAEVEESPETAAHPG-PIVVH 239 Query: 104 CVAGLGRAPVLVALALIEGGMKYEDAVQF------IRQKRRGAFNSKQL 146 C AG+GR +A + +K V +R R G + + Sbjct: 240 CSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQ 288 >6H8S-A nrPDB Length = 301 Score = 53.5 bits (127), Expect = 4e-08, Method: Composition-based stats. Identities = 22/90 (24%), Positives = 36/90 (40%), Gaps = 9/90 (10%) Query: 65 VLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCC--IAVHCVAGLGRAPVLVALALIEG 122 WP D P + + V+ ++E C I VHC AG+GR +A ++ Sbjct: 194 FTSWP-DQKTPDRAPPLLHLVREVEEAAQQEGPHCSPIIVHCSAGIGRTGCFIATSICCQ 252 Query: 123 GMKYEDAVQF------IRQKRRGAFNSKQL 146 ++ E V +RQ R G + + Sbjct: 253 QLRREGVVDILKTTCQLRQDRGGMIQTCEQ 282 >2Q47-A nrPDB Length = 151 Score = 50.5 bits (119), Expect = 4e-07, Method: Composition-based stats. Identities = 21/147 (14%), Positives = 48/147 (32%), Gaps = 7/147 (4%) Query: 9 PVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATY---DTTLVEKEGIHV 65 P+ + + + P +A + L+ G+ +I+ +C Y + ++ GI + Sbjct: 5 PLNFSMVDNGIFRSGFPDSANFSF----LQTLGLRSIIYLCPEPYPESNLQFLKSNGIRL 60 Query: 66 LDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALIEGGMK 125 + + P I D + + +E + +HC G R LV Sbjct: 61 FQFGIEGNKEPFVNIPDHKIRMALKVLLDEKNHPVLIHCKRGKHRTGCLVGCLRKLQKWC 120 Query: 126 YEDAVQFIRQKRRGAFNSKQLLYLEKY 152 ++ ++E + Sbjct: 121 LTSIFDEYQRFAAAKARVSDQRFMEIF 147 >2G6Z-A nrPDB Length = 211 Score = 47.8 bits (112), Expect = 2e-06, Method: Composition-based stats. Identities = 30/135 (22%), Positives = 59/135 (43%), Gaps = 20/135 (14%) Query: 8 APVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEKEGIHVLD 67 PVE+ + FL + +A+ +F+ L +T ++ V T + + +H Sbjct: 5 GPVEI----LPFLYLGSAYHASKCEFLANLH---ITALLNVSRRTSEACMTH---LHYKW 54 Query: 68 WPFDD----GAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALIE-G 122 P +D Q D++ V+ K G + VH AG+ R+P + L++ Sbjct: 55 IPVEDSHTADISSHFQEAIDFIDCVREK-----GGKVLVHSEAGISRSPTICMAYLMKTK 109 Query: 123 GMKYEDAVQFIRQKR 137 + ++A +I+Q+R Sbjct: 110 QFRLKEAFDYIKQRR 124 >2R0B-A nrPDB Length = 154 Score = 46.6 bits (109), Expect = 5e-06, Method: Composition-based stats. Identities = 27/118 (22%), Positives = 51/118 (43%), Gaps = 6/118 (5%) Query: 25 PTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEKEGIHVL-DWPFDDGAPPSNQIVDD 83 P ++ + + L+K+G+T I+ C K L + D A + + Sbjct: 17 PYSSAMKSKLPVLQKHGITHII--CIRQNIEANFIKPNFQQLFRYLVLDIADNPVENIIR 74 Query: 84 WLSLVKIKF--REEPGCCIAVHCVAGLGRAPVLVALALIEG-GMKYEDAVQFIRQKRR 138 + + K + G + VH AG+ R+ V ++E GMKY DA +++++R Sbjct: 75 FFPMTKEFIDGSLQMGGKVLVHGNAGISRSAAFVIAYIMETFGMKYRDAFAYVQERRF 132 >4YR8-G nrPDB Length = 167 Score = 46.6 bits (109), Expect = 6e-06, Method: Composition-based stats. Identities = 21/104 (20%), Positives = 44/104 (42%), Gaps = 19/104 (18%) Query: 54 DTTLVEKEGIHVL-----DWPFDDGAPPSN-----------QIVDDWLSLVKIKFREE-- 95 + L+++ GI + P D P S+ + + WL + Sbjct: 42 NKELMQQNGIGYVLNASNTCPKPDFIPESHFLRVPVNDSFCEKILPWLDKSVDFIEKAKA 101 Query: 96 PGCCIAVHCVAGLGRAPVLVALALIEG-GMKYEDAVQFIRQKRR 138 C+ VHC+AG+ R+ + +++ M ++A +F+++KR Sbjct: 102 SNGCVLVHCLAGISRSATIAIAYIMKRMDMSLDEAYRFVKEKRP 145 >6DR7-A nrPDB Length = 306 Score = 46.2 bits (108), Expect = 8e-06, Method: Composition-based stats. Identities = 25/103 (24%), Positives = 38/103 (36%), Gaps = 19/103 (18%) Query: 63 IHVLDWPFDDGAPPS------NQIVDDWLSLVKIKFREEPGCCIA--------VHCVAGL 108 +HV WP D G P S +VD + + + +A +HC AG+ Sbjct: 187 VHVTTWP-DFGVPESEVTKALASLVDQTAETKRNMYESKGSSAVADDSKLRPVIHCRAGV 245 Query: 109 GRAPVLVALALI----EGGMKYEDAVQFIRQKRRGAFNSKQLL 147 GR L+ + + ED V +R +R G K Sbjct: 246 GRTAQLIGAMCMNDSRNSQLSVEDMVSQMRVQRNGIMVQKDEQ 288 >3F41-A nrPDB Length = 629 Score = 46.2 bits (108), Expect = 8e-06, Method: Composition-based stats. Identities = 18/73 (24%), Positives = 31/73 (42%), Gaps = 3/73 (4%) Query: 46 VRVCEATYDTTLVEKEGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCV 105 V++ + LVEK G+H D PS +D++++ + + HC Sbjct: 482 VKIESVMTEQQLVEKNGLHYYRIAATDHIWPSAANIDEFINFTRTM---PANAWLHFHCQ 538 Query: 106 AGLGRAPVLVALA 118 AG GR +A+ Sbjct: 539 AGAGRTTAYMAMY 551 Score = 38.9 bits (89), Expect = 0.001, Method: Composition-based stats. Identities = 28/142 (19%), Positives = 53/142 (37%), Gaps = 21/142 (14%) Query: 28 ATLNKFIEELKKYGVT---TIVRVCEATYDTTLVEKEGIHVLDWPFDDGAPPSNQIVDDW 84 +T+ K V V + + +V++ G + D P + VD + Sbjct: 163 STVKSIYRFDDKKNVILSPVYVNYNKVRTEEEMVKQHGANYFRLTLQDHFRPDDPDVDKF 222 Query: 85 LSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALIEGG---MKYEDAVQFIRQKRRGAF 141 L K + + HC AG+GR + + + I + ++D +Q RQK G Sbjct: 223 LEFYKSLPK---DAWLHYHCYAGMGRTTIFMVMHDILKNAKDVSFDDIIQ--RQKLIGIV 277 Query: 142 NSKQ----------LLYLEKYR 153 + + Y+E+Y+ Sbjct: 278 DLSEIPDKKKNYGRKAYIERYQ 299 >3RGQ-A nrPDB Length = 156 Score = 45.5 bits (106), Expect = 1e-05, Method: Composition-based stats. Identities = 30/151 (19%), Positives = 58/151 (38%), Gaps = 8/151 (5%) Query: 15 KNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATY---DTTLVEKEGIHVLDWPFD 71 + L+ P + + + GV T+ E + + +K G+ L Sbjct: 6 IDHTVLLGALPLKNMTRRLVLDENVRGVITMNEEYETRFLCNTSKEWKKAGVEQLRLSTV 65 Query: 72 DGA-PPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALIE-GGMKYEDA 129 D P+ + + + G C+ VH AG R+ +VA LI+ E+A Sbjct: 66 DMTGVPTLANLHKGVQFALKY--QALGQCVYVHSKAGRSRSATMVAAYLIQVHNWSPEEA 123 Query: 130 VQFIRQKR-RGAFNSKQLLYLEKYRPKMRLR 159 ++ I + R + QL L+++ ++ R Sbjct: 124 IEAIAKIRSHISIRPSQLEVLKEFHKEITAR 154 >4KYQ-A nrPDB Length = 208 Score = 44.3 bits (103), Expect = 3e-05, Method: Composition-based stats. Identities = 24/82 (29%), Positives = 34/82 (41%), Gaps = 3/82 (3%) Query: 59 EKEGIHVLDWPFDDGAPPSN-QIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRA-PVLVA 116 ++ GI + P D P S + +S ++ E G + VHC AGLGRA V +A Sbjct: 74 KELGIRHMRRPAKDFDPLSLRSQLPKAVSSLEWAVSEGKG-RVYVHCSAGLGRAPGVSIA 132 Query: 117 LALIEGGMKYEDAVQFIRQKRR 138 M A + KR Sbjct: 133 YMYWFCDMNLNTAYDTLVSKRP 154 >3LJ8-A nrPDB Length = 146 Score = 44.3 bits (103), Expect = 3e-05, Method: Composition-based stats. Identities = 27/114 (23%), Positives = 47/114 (41%), Gaps = 21/114 (18%) Query: 34 IEELKKYGVTTIVRVCEATYDTTLVEKEG-IHVLDWPFDDG--------APPSNQIVDDW 84 +E L K G+ I+ V + EK G H P D P + + +D+ Sbjct: 21 LESLAKLGIRYILNVTPNLPN--FFEKNGDFHYKQIPISDHWSQNLSRFFPEAIEFIDEA 78 Query: 85 LSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALIEG-GMKYEDAVQFIRQKR 137 LS C + VHC+AG+ R+ + L++ + DA +++K+ Sbjct: 79 LSQ---------NCGVLVHCLAGVSRSVTVTVAYLMQKLHLSLNDAYDLVKRKK 123 >1ZZW-A nrPDB Length = 149 Score = 43.9 bits (102), Expect = 3e-05, Method: Composition-based stats. Identities = 22/114 (19%), Positives = 47/114 (41%), Gaps = 5/114 (4%) Query: 37 LKKYGVTTIVRVCEATYDTTLVEKEGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEP 96 +++ + ++ V EK + P D + + + + I+ + Sbjct: 25 MQRLNIGYVINVTTHL-PLYHYEKGLFNYKRLPATDSNKQNLRQYFE-EAFEFIEEAHQC 82 Query: 97 GCCIAVHCVAGLGRAPVLVALALIEG-GMKYEDAVQFIRQKRRGAFNSKQLLYL 149 G + +HC AG+ R+ +V L++ M DA +F++ KR S L ++ Sbjct: 83 GKGLLIHCQAGVSRSATIVIAYLMKHTRMTMTDAYKFVKGKRP--IISPNLNFM 134 >1M3G-A nrPDB Length = 145 Score = 43.9 bits (102), Expect = 4e-05, Method: Composition-based stats. Identities = 14/89 (15%), Positives = 34/89 (38%), Gaps = 6/89 (6%) Query: 63 IHVLDWPFDDG-APPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALI- 120 P +D + + + + + G + VH AG+ R+ + L+ Sbjct: 48 FRYKSIPVEDNQMVEISAWFQEAIGFIDWV--KNSGGRVLVHSQAGISRSATICLAYLMQ 105 Query: 121 EGGMKYEDAVQFIRQKRRGAFNSKQLLYL 149 ++ ++A F++Q+R S ++ Sbjct: 106 SRRVRLDEAFDFVKQRR--GVISPNFSFM 132 >1WRM-A nrPDB Length = 165 Score = 43.5 bits (101), Expect = 5e-05, Method: Composition-based stats. Identities = 33/127 (25%), Positives = 53/127 (41%), Gaps = 14/127 (11%) Query: 34 IEELKKYGVTTIVRVCEATYDTTLVEKEGIHVLDWPFDDGAPPSN--QIVDDWLSLVKIK 91 E+L K VT I+ V +D+ EG+ L P D +P N + + + + Sbjct: 25 AEQLSKNKVTHILSV----HDSARPMLEGVKYLCIPAAD-SPSQNLTRHFKESIKFIHEC 79 Query: 92 FREEPGCCIAVHCVAGLGRAPVLVALALIE-GGMKYEDAVQFIRQKR----RGAFNSKQL 146 C VHC+AG+ R+ LV ++ +EDA+ +R R +QL Sbjct: 80 RLRGESC--LVHCLAGVSRSVTLVIAYIMTVTDFGWEDALHTVRAGRSCANPNVGFQRQL 137 Query: 147 LYLEKYR 153 EK+ Sbjct: 138 QEFEKHE 144 >4MBB-A nrPDB Length = 184 Score = 43.5 bits (101), Expect = 5e-05, Method: Composition-based stats. Identities = 21/109 (19%), Positives = 39/109 (35%), Gaps = 5/109 (4%) Query: 49 CEATYDTTLVEKEGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGC--CIAVHCVA 106 Y E + L P ++ + + V +E I VH Sbjct: 72 YTQRYYKPEDLPETVPYLKIFTVGHQVPDDETIFKFKHAVNGFLKENKDNDKLIGVHSTH 131 Query: 107 GLGRAPVLVALALIE-GGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRP 154 GL R L+ LI+ G++ +DA++ + R ++ Y+E + Sbjct: 132 GLNRTGYLICRYLIDVEGVRPDDAIELFNRCRGHCL--ERQNYIEDLQN 178 >2OUD-A nrPDB Length = 177 Score = 43.5 bits (101), Expect = 5e-05, Method: Composition-based stats. Identities = 22/114 (19%), Positives = 47/114 (41%), Gaps = 5/114 (4%) Query: 37 LKKYGVTTIVRVCEATYDTTLVEKEGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEP 96 +++ + ++ V EK + P D + + + + I+ + Sbjct: 29 MQRLNIGYVINVTTHL-PLYHYEKGLFNYKRLPATDSNKQNLRQYFE-EAFEFIEEAHQC 86 Query: 97 GCCIAVHCVAGLGRAPVLVALALIEG-GMKYEDAVQFIRQKRRGAFNSKQLLYL 149 G + +HC AG+ R+ +V L++ M DA +F++ KR S L ++ Sbjct: 87 GKGLLIHCQAGVSRSATIVIAYLMKHTRMTMTDAYKFVKGKRP--IISPNLNFM 138 >2RF6-A nrPDB Length = 176 Score = 42.4 bits (98), Expect = 1e-04, Method: Composition-based stats. Identities = 24/143 (16%), Positives = 50/143 (34%), Gaps = 12/143 (8%) Query: 20 LITHNPTNATLNKFIEELKKYGVTTIVR-VCEATYDTTLVEKEGIHVLDWPF-DDGAPPS 77 ++T N L + + + V T D + I+++ P DD Sbjct: 31 IMTRVTNNVYLGNYKNAMDAPSSEVKFKYVLNLTMDKYTLPNSNINIIHIPLVDDTTTDI 90 Query: 78 NQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALIEGGMKYEDAVQF----- 132 ++ DD + + + + VH AG+ R+ ++ L+ + + F Sbjct: 91 SKYFDDVTAFLSKCDQRNE--PVLVHSAAGVNRSGAMILAYLMSKNKESLPMLYFLYVYH 148 Query: 133 -IRQKRRGAFNSK--QLLYLEKY 152 +R R + + +EKY Sbjct: 149 SMRDLRGAFVENPSFKRQIIEKY 171 >4B04-A nrPDB Length = 160 Score = 42.4 bits (98), Expect = 1e-04, Method: Composition-based stats. Identities = 21/106 (19%), Positives = 46/106 (43%), Gaps = 3/106 (2%) Query: 35 EELKKYGVTTIVRVCEATYDTTLVEKEGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFR- 93 EL++ G+T ++ + + T EG+ + + P+ + + + R Sbjct: 22 RELRRLGITHVLNASHSRWRGTPEAYEGLGIRYLGVEAHDSPAFDMSIHFQTAADFIHRA 81 Query: 94 -EEPGCCIAVHCVAGLGRAPVLV-ALALIEGGMKYEDAVQFIRQKR 137 +PG I VH G+ R+ LV A ++ + +A++ ++ R Sbjct: 82 LSQPGGKILVHSAVGVSRSATLVLAYLMLYHHLTLVEAIKKVKDHR 127 >5GTJ-A nrPDB Length = 181 Score = 42.4 bits (98), Expect = 1e-04, Method: Composition-based stats. Identities = 21/106 (19%), Positives = 46/106 (43%), Gaps = 3/106 (2%) Query: 35 EELKKYGVTTIVRVCEATYDTTLVEKEGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFR- 93 EL++ G+T ++ + + T EG+ + + P+ + + + R Sbjct: 43 RELRRLGITHVLNASHSRWRGTPEAYEGLGIRYLGVEAHDSPAFDMSIHFQTAADFIHRA 102 Query: 94 -EEPGCCIAVHCVAGLGRAPVLV-ALALIEGGMKYEDAVQFIRQKR 137 +PG I VH G+ R+ LV A ++ + +A++ ++ R Sbjct: 103 LSQPGGKILVHSAVGVSRSATLVLAYLMLYHHLTLVEAIKKVKDHR 148 >6N8N-Y nrPDB Length = 364 Score = 41.6 bits (96), Expect = 2e-04, Method: Composition-based stats. Identities = 35/161 (21%), Positives = 60/161 (37%), Gaps = 33/161 (20%) Query: 18 RFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEKEGIHVLDWPFDDGAP-- 75 R +I H P A N +T I+ V + + ++G + + P DD Sbjct: 25 RPIIDHRPLGAEFN----------ITHILSVIKFQVIPEYLIRKGYTLKNIPIDDDDVTD 74 Query: 76 ------PSNQIVDDWL---------SLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALI 120 +N+ +D L LV K + + G A HC AGL R+ + L+ Sbjct: 75 VLQYFDETNRFIDQCLFPNEVEYSPRLVDFKKKPQRGAVFA-HCQAGLSRSVTFIVAYLM 133 Query: 121 EG-GMKYEDAVQFIRQKRRGAFNS----KQLLYLEKYRPKM 156 G+ A+ +++K+ + +QL EK Sbjct: 134 YRYGLSLSMAMHAVKRKKPSVEPNENFMEQLHLFEKMGGDF 174 >6I28-A nrPDB Length = 168 Score = 41.2 bits (95), Expect = 2e-04, Method: Composition-based stats. Identities = 23/124 (18%), Positives = 44/124 (35%), Gaps = 4/124 (3%) Query: 33 FIEELKKYGVTTIVRVCEATYDTTLVEKEGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKF 92 F+ + V +++ A L +G H+ DD + + L Sbjct: 33 FVRQNNVGCVVSLIDSDVAPIKRALYLPDGDHLHVHCEDDAKCGALADNLEMLFNYLWLK 92 Query: 93 REEPGCCIAVHCVAGLGRAPVLVALALIEGG-MKYEDAVQFIRQKRRGAFNSKQLLYLEK 151 + +HC AG+ R+ L ++ + YE A Q++ KR ++E Sbjct: 93 IHNEHKTVLIHCHAGVSRSATLAIYYIMRTNQIDYEQAFQYVYGKR---AVHPSEHFVEL 149 Query: 152 YRPK 155 + K Sbjct: 150 LKGK 153 >6D67-A nrPDB Length = 520 Score = 40.8 bits (94), Expect = 3e-04, Method: Composition-based stats. Identities = 22/121 (18%), Positives = 46/121 (38%), Gaps = 21/121 (17%) Query: 37 LKKYGVTTIVRV---CEATYDTTLVEKEGIHVLDWPFDDGAPPSNQI----VDDWLSLVK 89 L G+T ++ V C ++ P +D D++ +K Sbjct: 395 LDALGITALINVSANCPNHFEGH------YQYKSIPVEDNHKADISSWFNEAIDFIDSIK 448 Query: 90 IKFREEPGCCIAVHCVAGLGRAPVLVALALIEG-GMKYEDAVQFIRQKRRGAFNSKQLLY 148 G + VH AG+ R+ + L+ +K ++A +F++Q+R + S + Sbjct: 449 -----NAGGRVFVHSQAGISRSATICLAYLMRTNRVKLDEAFEFVKQRR--SIISPNFSF 501 Query: 149 L 149 + Sbjct: 502 M 502 >2ESB-A nrPDB Length = 188 Score = 40.8 bits (94), Expect = 3e-04, Method: Composition-based stats. Identities = 18/81 (22%), Positives = 29/81 (35%), Gaps = 6/81 (7%) Query: 61 EGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFR--EEPGCCIAVHCVAGLGRAPVLVALA 118 E I + P D N + D+ + E +HC AG+ R+ L Sbjct: 62 EDIQYMQVPVAD---SPNSRLCDFFDPIADHIHSVEMKQGRTLLHCAAGVSRSAALCLAY 118 Query: 119 LIE-GGMKYEDAVQFIRQKRR 138 L++ M DA + + R Sbjct: 119 LMKYHAMSLLDAHTWTKSCRP 139 >4NX8-A nrPDB Length = 293 Score = 40.8 bits (94), Expect = 3e-04, Method: Composition-based stats. Identities = 15/74 (20%), Positives = 27/74 (36%), Gaps = 3/74 (4%) Query: 62 GIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALIE 121 G + D P + VD ++ V+ + HC AG GR + L + Sbjct: 167 GHQYVRLTVTDHVRPVDSEVDRFIESVRAL---PENAWVHFHCRAGKGRTTTFMVLYDML 223 Query: 122 GGMKYEDAVQFIRQ 135 K + + I++ Sbjct: 224 KNAKTDSFEEIIKR 237 >2WGP-A nrPDB Length = 190 Score = 40.8 bits (94), Expect = 3e-04, Method: Composition-based stats. Identities = 22/104 (21%), Positives = 38/104 (36%), Gaps = 7/104 (6%) Query: 37 LKKYGVTTIVRVCEATYDTTLVEKEGIHVLDWPFDDGA-PPSNQIVDDWLSLVKIKFREE 95 L+ G+T IV AT + + P D P D + R+ Sbjct: 47 LQARGITCIVN---ATIEIPNFNWPQFEYVKVPLADMPHAPIGLYFDTVADKIHSVSRKH 103 Query: 96 PGCCIAVHCVAGLGRAPVLVALALIE-GGMKYEDAVQFIRQKRR 138 VHC AG+ R+ L L++ + +A +++ +R Sbjct: 104 --GATLVHCAAGVSRSATLCIAYLMKFHNVCLLEAYNWVKARRP 145 >6E3B-A nrPDB Length = 169 Score = 40.8 bits (94), Expect = 3e-04, Method: Composition-based stats. Identities = 20/156 (12%), Positives = 38/156 (24%) Query: 9 PVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEKEGIHVLDW 68 P ++ + P + E LK + ++ + ++ GI + Sbjct: 7 PENFSHVVGEIYRSSFPRQENFSFLHERLKLKSILVLIPEEYPQENLNFLKLTGIKLYQV 66 Query: 69 PFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALIEGGMKYED 128 P I L+ I +H G R L+ Sbjct: 67 GMSGNKEPFVNIPSHLLTKALEIVLNPANQPILIHSNRGKHRTGCLIGCIRKLQNWSLTM 126 Query: 129 AVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFKDSN 164 R+ + ++E Y R N Sbjct: 127 IFDEYRRFAFPKARALDQQFIEMYDDDEIKRIASKN 162 >1G4W-R nrPDB Length = 383 Score = 40.4 bits (93), Expect = 4e-04, Method: Composition-based stats. Identities = 15/66 (22%), Positives = 27/66 (40%), Gaps = 8/66 (12%) Query: 63 IHVLDWPFDDGAPPSNQIVDDWLSLVKIKFR-------EEPGCCIAVHCVAGLGRAPVLV 115 +HV +WP D PS ++ VK + +HC+ G+GR + Sbjct: 274 LHVKNWP-DHQPLPSTDQLEYLADRVKNSNQNGAPGRSSSDKHLPMIHCLGGVGRTGTMA 332 Query: 116 ALALIE 121 A +++ Sbjct: 333 AALVLK 338 >4TVV-A nrPDB Length = 314 Score = 40.1 bits (92), Expect = 4e-04, Method: Composition-based stats. Identities = 22/108 (20%), Positives = 41/108 (37%), Gaps = 12/108 (11%) Query: 29 TLNKFIEELKKYGVTTIVRV--CEATYDTTLVEKEGIHVLDWPFDDGAPPSNQIVDDWLS 86 T+ +++ + G + +V E Y V K+G D P + VD ++ Sbjct: 156 TVPQYVAKQYSQGKSMVVSTVKNEEYY----VYKKGFDYYRIFISDHRAPLDSEVDALVA 211 Query: 87 LVKIKFREEPGCCIAVHCVAGLGRAPVLVALALIEGG---MKYEDAVQ 131 L+K VHC G GR + A+ + + +E+ + Sbjct: 212 LIK---NNPEDTWYHVHCRGGKGRTTTVFAMFDMLKNADKVSFEEIIA 256 >5XJV-A nrPDB Length = 185 Score = 40.1 bits (92), Expect = 5e-04, Method: Composition-based stats. Identities = 26/111 (23%), Positives = 42/111 (37%), Gaps = 14/111 (12%) Query: 36 ELKKYGVTTIVRVC--------EATYDTTLVEKEGIHVLDWPFDDGAPPSNQIVDDWLSL 87 EL K G+T ++ + + V G+ D P D D++ Sbjct: 58 ELWKLGITHVLNAAHKGLYAQGGPDFYGSSVSYLGVPAHDLP-DFDISAYFSSAADFI-- 114 Query: 88 VKIKFREEPGCCIAVHCVAGLGRAPVLV-ALALIEGGMKYEDAVQFIRQKR 137 + PG + VH V G+ R+ LV A ++ + AV +RQ R Sbjct: 115 --HRALNTPGAKVLVHSVVGVSRSATLVLAYLMLHQRLSLRQAVITVRQHR 163 >1J4X-A nrPDB Length = 184 Score = 40.1 bits (92), Expect = 6e-04, Method: Composition-based stats. Identities = 25/118 (21%), Positives = 47/118 (39%), Gaps = 7/118 (5%) Query: 27 NATLNKFIEELKKYGVTTIVRVCE------ATYDTTLVEKEGIHVLDWPFDDGAPPSNQI 80 NA++ + I +L+K G+T ++ E + + GI L +D + Sbjct: 40 NASVAQDIPKLQKLGITHVLNAAEGRSFMHVNTNANFYKDSGITYLGIKANDTQEFNLSA 99 Query: 81 VDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALIEGG-MKYEDAVQFIRQKR 137 + + + + + VH G R+P LV L+ M + A+ +RQ R Sbjct: 100 YFERAADFIDQALAQKNGRVLVHSREGYSRSPTLVIAYLMMRQKMDVKSALSIVRQNR 157 >4JMK-A nrPDB Length = 152 Score = 39.7 bits (91), Expect = 7e-04, Method: Composition-based stats. Identities = 22/115 (19%), Positives = 43/115 (37%), Gaps = 21/115 (18%) Query: 54 DTTLVEKEGIHVL-----DWPFDDGAPPSN-----------QIVDDWLSLVKIKFREE-- 95 + L+ + GI + P D S + + WL + Sbjct: 20 NKDLMTQNGISYVLNASNSCPKPDFICESRFMRVPINDNYCEKLLPWLDKSIEFIDKAKL 79 Query: 96 PGCCIAVHCVAGLGRAPVLVALALIEG-GMKYEDAVQFIRQKRRGAFNSKQLLYL 149 C + VH +AG+ R+ + +++ GM +DA +F++ +R S +L Sbjct: 80 SSCQVIVHSLAGISRSATIAIAYIMKTMGMSSDDAYRFVKDRRPS--ISPNFNFL 132 >4R30-A nrPDB Length = 184 Score = 38.9 bits (89), Expect = 0.001, Method: Composition-based stats. Identities = 21/107 (19%), Positives = 39/107 (36%), Gaps = 6/107 (5%) Query: 56 TLVEKEGIHVLDWPFDDGAPP-SNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGR-APV 113 L +EG+ + P D + Q++ + L+ E G + VH AG+GR Sbjct: 72 KLYREEGLAYIWMPTPDMSTEGRVQMLPQAVCLLHALL--EKGHIVYVHSNAGVGRSTAA 129 Query: 114 LVALALIEGGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRF 160 + G F+ KR + ++ L + + +F Sbjct: 130 VCGWLQYVMGWNLRKVQYFLMAKRPAVYIDEEA--LARAQEDFFQKF 174 >4RKK-A nrPDB Length = 332 Score = 38.5 bits (88), Expect = 0.001, Method: Composition-based stats. Identities = 21/107 (19%), Positives = 39/107 (36%), Gaps = 6/107 (5%) Query: 56 TLVEKEGIHVLDWPFDDGAPP-SNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGR-APV 113 L +EG+ + P D + Q++ + L+ E G + VH AG+GR Sbjct: 222 KLYREEGLAYIWMPTPDMSTEGRVQMLPQAVCLLHALL--EKGHIVYVHSNAGVGRSTAA 279 Query: 114 LVALALIEGGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRF 160 + G F+ KR + ++ L + + +F Sbjct: 280 VCGWLQYVMGWNLRKVQYFLMAKRPAVYIDEEA--LARAQEDFFQKF 324 >3EZZ-A nrPDB Length = 144 Score = 38.5 bits (88), Expect = 0.002, Method: Composition-based stats. Identities = 21/118 (17%), Positives = 46/118 (38%), Gaps = 15/118 (12%) Query: 37 LKKYGVTTIVRVCEATYDTTLVEKEGIHVLDWPFDDGAPPSNQI----VDDWLSLVKIKF 92 L G+T ++ V D + P +D +++ VK Sbjct: 25 LDALGITALLNVSS---DCPNHFEGHYQYKCIPVEDNHKADISSWFMEAIEYIDAVKDC- 80 Query: 93 REEPGCCIAVHCVAGLGRAPVLV-ALALIEGGMKYEDAVQFIRQKRRGAFNSKQLLYL 149 + VH AG+ R+ + A +++ ++ E+A +F++Q+R + S ++ Sbjct: 81 ----RGRVLVHSQAGISRSATICLAYLMMKKRVRLEEAFEFVKQRR--SIISPNFSFM 132 >1YZ4-A nrPDB Length = 160 Score = 38.1 bits (87), Expect = 0.002, Method: Composition-based stats. Identities = 25/132 (18%), Positives = 50/132 (37%), Gaps = 10/132 (7%) Query: 34 IEELKKYGVTTIVRVCEATYDTTLVEKEGIHVLDWPFDDGAP--PSNQIVDDWLSLVKIK 91 ++L + G I + + ++ I L P D P P + + ++ + Sbjct: 23 AKDLDQLGRNKITHIISIHESPQPLLQD-ITYLRIPVAD-TPEVPIKKHFKECINFIHCC 80 Query: 92 FREEPGCCIAVHCVAGLGRAPVLVALALIE-GGMKYEDAVQFIRQKRRGAFNSK---QLL 147 G VH AG+ R+ +V ++ G+ + D ++ I+ R A + Q L Sbjct: 81 --RLNGGNCLVHSFAGISRSTTIVTAYVMTVTGLGWRDVLEAIKATRPIANPNPGFRQQL 138 Query: 148 YLEKYRPKMRLR 159 + +LR Sbjct: 139 EEFGWASSQKLR 150 >4Y2E-A nrPDB Length = 149 Score = 37.4 bits (85), Expect = 0.003, Method: Composition-based stats. Identities = 22/104 (21%), Positives = 41/104 (39%), Gaps = 7/104 (6%) Query: 37 LKKYGVTTIVRVCEATYDTTLVEKEG-IHVLDWPFDDGAPPSNQIVD-DWLSLVKIKFRE 94 L KYG+ I+ V + E G P D + + +S + Sbjct: 27 LGKYGIKYILNVTPNLPNA--FEHGGEFTYKQIPISDHWSQNLSQFFPEAISFIDE--AR 82 Query: 95 EPGCCIAVHCVAGLGRAPVLVALALIEG-GMKYEDAVQFIRQKR 137 C + VH +AG+ R+ + L++ + DA F+++K+ Sbjct: 83 SKKCGVLVHSLAGISRSVTVTVAYLMQKMNLSLNDAYDFVKRKK 126 >2M3V-A nrPDB Length = 193 Score = 36.2 bits (82), Expect = 0.007, Method: Composition-based stats. Identities = 15/107 (14%), Positives = 44/107 (41%), Gaps = 9/107 (8%) Query: 34 IEELKKYGVTTIVRVCEATYDTTLVEKEGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFR 93 ++ L+ V + ++ + + + + + V+ P ++ LS+++ Sbjct: 45 LQRLQVKTVVSFIKDDDRAW----LGQAPVRVVSLPTHADRVDDAEV----LSVLRQLQA 96 Query: 94 EEPGCCIAVHCVAGLGRAPVLVALA-LIEGGMKYEDAVQFIRQKRRG 139 E + +HC G R + A+ ++ G + A++ +++ G Sbjct: 97 AEREGPVLMHCKHGNNRTGLFAAMYRIVVQGWDKQAALEEMQRGGFG 143 >3D1Q-A nrPDB Length = 340 Score = 36.2 bits (82), Expect = 0.008, Method: Composition-based stats. Identities = 14/69 (20%), Positives = 28/69 (40%), Gaps = 3/69 (4%) Query: 47 RVCEATYDTTLVEKEGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVA 106 RV + + + E G+ D P+ + +D +L+ + + + HC A Sbjct: 192 RVQKVQTEQEVAEAAGMRYFRIAATDHVWPTPENIDRFLAFYRTLPQ---DAWLHFHCEA 248 Query: 107 GLGRAPVLV 115 G+GR + Sbjct: 249 GVGRTTAFM 257 >1MKP-A nrPDB Length = 144 Score = 35.8 bits (81), Expect = 0.010, Method: Composition-based stats. Identities = 28/133 (21%), Positives = 50/133 (37%), Gaps = 16/133 (12%) Query: 9 PVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEKEG-IHVLD 67 PVE+ + FL ++T +EE G+ I+ V + E G Sbjct: 4 PVEI----LPFLYLGCAKDSTNLDVLEEF---GIKYILNVTPNLPNL--FENAGEFKYKQ 54 Query: 68 WPFDDGAPPSNQIVDDWLSLVKIKFREEPG--CCIAVHCVAGLGRAPVLVALALIEG-GM 124 P D +Q + + E G C + VH +AG+ R+ + L++ + Sbjct: 55 IPISDHW---SQNLSQFFPEAISFIDEARGKNCGVLVHSLAGISRSVTVTVAYLMQKLNL 111 Query: 125 KYEDAVQFIRQKR 137 DA ++ K+ Sbjct: 112 SMNDAYDIVKMKK 124 >4R0S-A nrPDB Length = 218 Score = 35.4 bits (80), Expect = 0.012, Method: Composition-based stats. Identities = 16/107 (14%), Positives = 43/107 (40%), Gaps = 9/107 (8%) Query: 34 IEELKKYGVTTIVRVCEATYDTTLVEKEGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFR 93 ++ L+ V + ++ + + + + + VL P ++ LS+++ Sbjct: 70 LQRLQVKTVVSFIKDDDRAW----LGQAPVRVLSLPTHADRVDDAEV----LSVLRQLQA 121 Query: 94 EEPGCCIAVHCVAGLGRAPVLVALA-LIEGGMKYEDAVQFIRQKRRG 139 E + +HC G R + A+ ++ G + A++ ++ G Sbjct: 122 AEREGPVLMHCKHGNNRTGLFAAMYRIVVQGWDKQAALEEMQHGGFG 168 >5NCR-A nrPDB Length = 181 Score = 32.0 bits (71), Expect = 0.15, Method: Composition-based stats. Identities = 12/64 (18%), Positives = 21/64 (32%), Gaps = 1/64 (1%) Query: 61 EGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALI 120 GI P D + + L + + E VH VAG+ R+ ++ Sbjct: 70 AGITAYHIPLRDDDKTNIASIMPALVKLLARL-EAEQKPTLVHSVAGVNRSGAAAMGYVM 128 Query: 121 EGGM 124 + Sbjct: 129 HKRL 132 >4KI9-A nrPDB Length = 163 Score = 31.6 bits (70), Expect = 0.17, Method: Composition-based stats. Identities = 12/62 (19%), Positives = 30/62 (48%), Gaps = 2/62 (3%) Query: 94 EEPGCCIAVHCVAGLGRAPVLVALALIEG-GMKYEDAVQFIRQKRRGAFNSKQLLY-LEK 151 G + VH AG+ R+ ++ L++ + +E A + ++ + A ++ + L+ Sbjct: 79 RAEGRAVLVHSHAGVSRSVAIITAFLMKTDQLPFEKAYEKLQILKPEAKMNEGFEWQLKL 138 Query: 152 YR 153 Y+ Sbjct: 139 YQ 140 >2OZ5-A nrPDB Length = 296 Score = 31.6 bits (70), Expect = 0.19, Method: Composition-based stats. Identities = 12/38 (31%), Positives = 16/38 (42%) Query: 96 PGCCIAVHCVAGLGRAPVLVALALIEGGMKYEDAVQFI 133 G + HC AG R +VAL L G+ + V Sbjct: 172 AGRPVLTHCFAGKDRTGFVVALVLEAVGLDRDVIVADY 209 >2QFY-A nrPDB Length = 427 Score = 30.4 bits (67), Expect = 0.43, Method: Composition-based stats. Identities = 24/131 (18%), Positives = 46/131 (35%), Gaps = 8/131 (6%) Query: 1 MARMNRPAPVE-VTYKNMRFLITH--NPTNATLNKFIEELKKYGVTTIVRVCEATYDTTL 57 MA N +E + + + I N +T N +++ V EA Y + Sbjct: 196 MAMYNTDESIEGFAHSSFKLAIDKKLNLFLSTKNTILKKYDGRFKDIFQEVYEAQY-KSK 254 Query: 58 VEKEGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVAL 117 E+ GIH DD + ++ +K + +A G G ++ ++ Sbjct: 255 FEQLGIHYEHRLIDDMVAQMIKSKGGFIMALKNYDGDVQSDIVA----QGFGSLGLMTSI 310 Query: 118 ALIEGGMKYED 128 + G +E Sbjct: 311 LVTPDGKTFES 321 >4D3P-A nrPDB Length = 147 Score = 30.0 bits (66), Expect = 0.58, Method: Composition-based stats. Identities = 20/108 (18%), Positives = 37/108 (34%), Gaps = 18/108 (16%) Query: 50 EATYDTTLVEKEGIHVL--------DWPFDDGAPPSNQIVD----DWLSLVKIKFR---- 93 +A +D ++K + + + D S I+D + LS F Sbjct: 21 DAAHDLDTLKKNKVTHILNVAYGVENAFLSDFTYKSISILDLPETNILSYFPECFEFIEE 80 Query: 94 -EEPGCCIAVHCVAGLGRAPVLVALALI-EGGMKYEDAVQFIRQKRRG 139 + + VH AG+ RA +V L+ + A ++ R Sbjct: 81 AKRKDGVVLVHANAGVSRAAAIVIGFLMNSEQTSFTSAFSLVKNARPS 128 >4CBI-A nrPDB Length = 516 Score = 28.9 bits (63), Expect = 1.1, Method: Composition-based stats. Identities = 15/95 (15%), Positives = 30/95 (31%), Gaps = 9/95 (9%) Query: 1 MARMNRPAPVEVTYKNMR----FLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTT 56 MAR + P P+++ Y + L + + + + T Sbjct: 415 MARTDHPEPIQLAYNSYETQVPVLFPKIRNGEVTDTY-DNYTFLNARKLGDDVPPYVYAT 473 Query: 57 LVEKEGIHV--LDWPFD--DGAPPSNQIVDDWLSL 87 E + + LDWP G + + + + L Sbjct: 474 EDEDLAVELLGLDWPDPGNQGTVEAGRALKQVVGL 508 >4PYH-A nrPDB Length = 294 Score = 28.5 bits (62), Expect = 1.4, Method: Composition-based stats. Identities = 14/42 (33%), Positives = 20/42 (47%), Gaps = 1/42 (2%) Query: 97 GCCIAVHCVAGLGRAPVLVALALI-EGGMKYEDAVQFIRQKR 137 G VH AG+GRAP + + G K +A + + KR Sbjct: 106 GGVTYVHSTAGMGRAPAVALTYMFWVQGYKLMEAHKLLMSKR 147 >5WX1-A nrPDB Length = 733 Score = 28.1 bits (61), Expect = 1.9, Method: Composition-based stats. Identities = 15/95 (15%), Positives = 30/95 (31%), Gaps = 9/95 (9%) Query: 1 MARMNRPAPVEVTYKNMR----FLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTT 56 MAR + P P+++ Y + L + + + + T Sbjct: 640 MARTDHPEPIQLAYNSYETQVPVLFPKIRNGEVTDSY-DNYTFLNARKLGDDVPPYVYAT 698 Query: 57 LVEKEGIHV--LDWPFD--DGAPPSNQIVDDWLSL 87 E + + LDWP G + + + + L Sbjct: 699 EDEDLAVELLGLDWPDPGNQGTVEAGRALKQVVGL 733 >5MIO-C nrPDB Length = 573 Score = 27.7 bits (60), Expect = 2.7, Method: Composition-based stats. Identities = 15/73 (20%), Positives = 29/73 (39%), Gaps = 6/73 (8%) Query: 1 MARMNRPAPVEVTYKNMRFLITHNPTNATLN----KFIEELKKYGVTTIVRVCEATYDTT 56 M RM R + ++ N F ATL + ++++ + VR + + Sbjct: 1 MGRMKRAQEYDSSFPNWEFARMIKEFRATLECHPLTMTDPIEEHRICVCVR--KRPLNKQ 58 Query: 57 LVEKEGIHVLDWP 69 + K+ I V+ P Sbjct: 59 ELAKKEIDVISIP 71 >5WSO-A nrPDB Length = 476 Score = 27.7 bits (60), Expect = 2.8, Method: Composition-based stats. Identities = 15/95 (15%), Positives = 28/95 (29%), Gaps = 9/95 (9%) Query: 1 MARMNRPAPVEVTYKNMR----FLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTT 56 MAR + P P+++ Y + L + + E + T Sbjct: 383 MARTDHPEPIQLAYNSYEVQVPVLFPKIRNGEVTDTY-ENYSFLNARKLGEDVPVYIYAT 441 Query: 57 LVEKEGIHV--LDWPFD--DGAPPSNQIVDDWLSL 87 E + + LDWP + + + L Sbjct: 442 EDEDLAVDLLGLDWPDPGNQQVVETGKALKQVTGL 476 >2EH6-A nrPDB Length = 375 Score = 27.0 bits (58), Expect = 5.0, Method: Composition-based stats. Identities = 15/71 (21%), Positives = 28/71 (39%), Gaps = 3/71 (4%) Query: 46 VRVCEATYDTTLVEKEGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCV 105 + ++ Y E GI + + G N+ +D+LS ++ +E+ I Sbjct: 159 LNDIDSVYKLLDEETAGIIIEVIQGEGGV---NEASEDFLSKLQEICKEKDVLLIIDEVQ 215 Query: 106 AGLGRAPVLVA 116 G+GR A Sbjct: 216 TGIGRTGEFYA 226 >4PNE-A nrPDB Length = 302 Score = 26.6 bits (57), Expect = 6.4, Method: Composition-based stats. Identities = 10/41 (24%), Positives = 14/41 (34%) Query: 63 IHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVH 103 + P G P++Q V LV G A+H Sbjct: 21 MQRSGIPVLPGGAPTSQQVGQMYDLVTPLLNSVAGGPCAIH 61 >1KF9-A nrPDB Length = 191 Score = 26.2 bits (56), Expect = 7.6, Method: Composition-based stats. Identities = 11/31 (35%), Positives = 15/31 (48%) Query: 53 YDTTLVEKEGIHVLDWPFDDGAPPSNQIVDD 83 YD +EGI L +DG+P + QI Sbjct: 111 YDLLKDLEEGIQTLMGRLEDGSPRTGQIFKQ 141 >2HFB-A nrPDB Length = 409 Score = 25.8 bits (55), Expect = 9.7, Method: Composition-based stats. Identities = 11/67 (16%), Positives = 20/67 (29%), Gaps = 9/67 (13%) Query: 31 NKFIEELKKYGVTTIVRVCEATYDTTLVEKEGIHVLDWPFDDGAPPSNQIVDDWLSLVKI 90 K+ K Y V Y+ E+ G+ V P + + + + Sbjct: 116 EKYAVNEKVYNVPFTANAYGIYYNKDKFEELGLKV---------PETWDEFEQLVKDIVA 166 Query: 91 KFREEPG 97 K + G Sbjct: 167 KGQTPFG 173 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.313 0.132 0.362 Lambda K H 0.267 0.0406 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 6,457,782 Number of Sequences: 36641 Number of extensions: 224779 Number of successful extensions: 902 Number of sequences better than 10.0: 121 Number of HSP's better than 10.0 without gapping: 131 Number of HSP's successfully gapped in prelim test: 71 Number of HSP's that attempted gapping in prelim test: 718 Number of HSP's gapped (non-prelim): 214 length of query: 173 length of database: 10,336,785 effective HSP length: 90 effective length of query: 83 effective length of database: 7,039,095 effective search space: 584244885 effective search space used: 584244885 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.4 bits) S2: 55 (25.8 bits)