BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q63707 (395 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 1UUO-A nrPDB 730 0.0 3U2O-A nrPDB 703 0.0 6I4B-A nrPDB 288 3e-78 1TV5-A nrPDB 270 7e-73 4XQ6-A nrPDB 234 4e-62 1F76-A nrPDB 228 3e-60 6B8S-A nrPDB 218 4e-57 5UE9-A nrPDB 93 2e-19 1EP3-A nrPDB 91 9e-19 4WZH-A nrPDB 79 3e-15 1JUE-A nrPDB 79 3e-15 5XFW-A nrPDB 78 8e-15 3W7D-A nrPDB 75 5e-14 3GZ3-A nrPDB 73 2e-13 3OIX-A nrPDB 71 8e-13 5ZBN-A nrPDB 36 0.022 1AL8-A nrPDB 36 0.036 3SGZ-A nrPDB 35 0.057 2CDH-0 nrPDB 35 0.066 2RDM-A nrPDB 31 0.77 5Y2D-A nrPDB 31 1.1 5Y28-A nrPDB 30 1.3 3PUD-A nrPDB 30 1.5 4Q4K-A nrPDB 30 1.7 2Z6J-A nrPDB 30 2.2 2RDU-A nrPDB 30 2.7 3L5A-A nrPDB 29 2.9 3FI9-A nrPDB 29 3.4 3EBB-A nrPDB 29 3.5 6DX9-A nrPDB 29 4.6 3EUH-C nrPDB 28 5.3 4PE8-A nrPDB 28 5.6 4N6F-A nrPDB 28 7.9 >1UUO-A nrPDB Length = 372 Score = 730 bits (1884), Expect = 0.0, Method: Compositional matrix adjust. Identities = 366/366 (100%), Positives = 366/366 (100%) Query: 30 ATGDDHFYAEYLMPGLQRLLDPESAHRLAVRVTSLGLLPRATFQDSDMLEVKVLGHKFRN 89 ATGDDHFYAEYLMPGLQRLLDPESAHRLAVRVTSLGLLPRATFQDSDMLEVKVLGHKFRN Sbjct: 7 ATGDDHFYAEYLMPGLQRLLDPESAHRLAVRVTSLGLLPRATFQDSDMLEVKVLGHKFRN 66 Query: 90 PVGIAAGFDKNGEAVDGLYKLGFGFVEVGSVTPQPQEGNPRPRVFRLPEDQAVINRYGFN 149 PVGIAAGFDKNGEAVDGLYKLGFGFVEVGSVTPQPQEGNPRPRVFRLPEDQAVINRYGFN Sbjct: 67 PVGIAAGFDKNGEAVDGLYKLGFGFVEVGSVTPQPQEGNPRPRVFRLPEDQAVINRYGFN 126 Query: 150 SHGLSVVEHRLRARQQKQAQLTADGLPLGINLGKNKTSEDAAADYAEGVRTLGPLADYLV 209 SHGLSVVEHRLRARQQKQAQLTADGLPLGINLGKNKTSEDAAADYAEGVRTLGPLADYLV Sbjct: 127 SHGLSVVEHRLRARQQKQAQLTADGLPLGINLGKNKTSEDAAADYAEGVRTLGPLADYLV 186 Query: 210 VNVSSPNTAGLRSLQGKTELRHLLSKVLQERDALKGTRKPAVLVKIAPDLTAQDKEDIAS 269 VNVSSPNTAGLRSLQGKTELRHLLSKVLQERDALKGTRKPAVLVKIAPDLTAQDKEDIAS Sbjct: 187 VNVSSPNTAGLRSLQGKTELRHLLSKVLQERDALKGTRKPAVLVKIAPDLTAQDKEDIAS 246 Query: 270 VARELGIDGLIVTNTTVSRPVGLQGALRSETGGLSGKPLRDLSTQTIREMYALTQGRIPI 329 VARELGIDGLIVTNTTVSRPVGLQGALRSETGGLSGKPLRDLSTQTIREMYALTQGRIPI Sbjct: 247 VARELGIDGLIVTNTTVSRPVGLQGALRSETGGLSGKPLRDLSTQTIREMYALTQGRIPI 306 Query: 330 IGVGGVSSGQDALEKIQAGASLVQLYTALIFLGPPVVVRVKRELEALLKERGFTTVTDAI 389 IGVGGVSSGQDALEKIQAGASLVQLYTALIFLGPPVVVRVKRELEALLKERGFTTVTDAI Sbjct: 307 IGVGGVSSGQDALEKIQAGASLVQLYTALIFLGPPVVVRVKRELEALLKERGFTTVTDAI 366 Query: 390 GADHRR 395 GADHRR Sbjct: 367 GADHRR 372 >3U2O-A nrPDB Length = 395 Score = 703 bits (1815), Expect = 0.0, Method: Compositional matrix adjust. Identities = 350/395 (88%), Positives = 369/395 (93%) Query: 1 MAWRQLRKRALDAVIILGGGGLLFTSYLTATGDDHFYAEYLMPGLQRLLDPESAHRLAVR 60 MAWR L+KRA DAVIILGGGGLLF SYL ATGD+ FYAE+LMP LQ LLDPESAHRLAVR Sbjct: 1 MAWRHLKKRAQDAVIILGGGGLLFASYLMATGDERFYAEHLMPTLQGLLDPESAHRLAVR 60 Query: 61 VTSLGLLPRATFQDSDMLEVKVLGHKFRNPVGIAAGFDKNGEAVDGLYKLGFGFVEVGSV 120 TSLGLLPRA FQDSDMLEV+VLGHKFRNPVGIAAGFDK+GEAVDGLYK+GFGFVE+GSV Sbjct: 61 FTSLGLLPRARFQDSDMLEVRVLGHKFRNPVGIAAGFDKHGEAVDGLYKMGFGFVEIGSV 120 Query: 121 TPQPQEGNPRPRVFRLPEDQAVINRYGFNSHGLSVVEHRLRARQQKQAQLTADGLPLGIN 180 TP+PQEGNPRPRVFRLPEDQAVINRYGFNSHGLSVVEHRLRARQQKQA+LT DGLPLG+N Sbjct: 121 TPKPQEGNPRPRVFRLPEDQAVINRYGFNSHGLSVVEHRLRARQQKQAKLTEDGLPLGVN 180 Query: 181 LGKNKTSEDAAADYAEGVRTLGPLADYLVVNVSSPNTAGLRSLQGKTELRHLLSKVLQER 240 LGKNKTS DAA DYAEGVR LGPLADYLVVNVSSPNTAGLRSLQGK ELR LL+KVLQER Sbjct: 181 LGKNKTSVDAAEDYAEGVRVLGPLADYLVVNVSSPNTAGLRSLQGKAELRRLLTKVLQER 240 Query: 241 DALKGTRKPAVLVKIAPDLTAQDKEDIASVARELGIDGLIVTNTTVSRPVGLQGALRSET 300 D L+ +PAVLVKIAPDLT+QDKEDIASV +ELGIDGLIVTNTTVSRP GLQGALRSET Sbjct: 241 DGLRRVHRPAVLVKIAPDLTSQDKEDIASVVKELGIDGLIVTNTTVSRPAGLQGALRSET 300 Query: 301 GGLSGKPLRDLSTQTIREMYALTQGRIPIIGVGGVSSGQDALEKIQAGASLVQLYTALIF 360 GGLSGKPLRDLSTQTIREMYALTQGR+PIIGVGGVSSGQDALEKI+AGASLVQLYTAL F Sbjct: 301 GGLSGKPLRDLSTQTIREMYALTQGRVPIIGVGGVSSGQDALEKIRAGASLVQLYTALTF 360 Query: 361 LGPPVVVRVKRELEALLKERGFTTVTDAIGADHRR 395 GPPVV +VKRELEALLKE+GF VTDAIGADHRR Sbjct: 361 WGPPVVGKVKRELEALLKEQGFGGVTDAIGADHRR 395 >6I4B-A nrPDB Length = 405 Score = 288 bits (737), Expect = 3e-78, Method: Compositional matrix adjust. Identities = 154/396 (38%), Positives = 227/396 (57%), Gaps = 21/396 (5%) Query: 17 LGGGGLLFTSYLTATGDDHFYAEYLMPGLQRLLDPESAHRLAVRVTSLGLLPRATFQDSD 76 LG L F S + + F + + + +D E H L + + +LP T DS Sbjct: 13 LGTENLYFQSMFESYNPEFFLYDIFLKFCLKYIDGEICHDLFLLLGKYNILPYDTSNDSI 72 Query: 77 MLEVKVLGHKFRNPVGIAAGFDKNGEAVDGLYKLGFGFVEVGSVTPQPQEGNPRPRVFRL 136 + F NP G+AAGFDKNG +D + KLGF F+E+G++TP+ Q GN +PR+FR Sbjct: 73 YACTNIKHLDFINPFGVAAGFDKNGVCIDSILKLGFSFIEIGTITPRGQTGNAKPRIFRD 132 Query: 137 PEDQAVINRYGFNSHGLSVVEHRL---RARQQKQAQLTADGLPLGINLGKNKTSEDAAAD 193 E +++IN GFN+ G V L R RQ++ L+ +G+++GKNK + + D Sbjct: 133 VESRSIINSCGFNNMGCDKVTENLILFRKRQEEDKLLSKH--IVGVSIGKNKDTVNIVDD 190 Query: 194 YAEGVRTLGPLADYLVVNVSSPNTAGLRSLQGKTELRHLLSKVLQERDALKGT------- 246 + +G ADY+ +NVSSPNT GLR Q +L++++ V +E D L+ Sbjct: 191 LKYCINKIGRYADYIAINVSSPNTPGLRDNQEAGKLKNIILSVKEEIDNLEKNNIMNDEF 250 Query: 247 -------RKPAVLVKIAPDLTAQDKEDIASVARELGIDGLIVTNTTVSRPVGLQGALRSE 299 +KP V VK+APDL + K++IA V E IDG+I++NTT + + ++ Sbjct: 251 LWFNTTKKKPLVFVKLAPDLNQEQKKEIADVLLETNIDGMIISNTTTQ--INDIKSFENK 308 Query: 300 TGGLSGKPLRDLSTQTIREMYALTQGRIPIIGVGGVSSGQDALEKIQAGASLVQLYTALI 359 GG+SG L+D+ST+ I EMY T +IPII GG+ SG DALEKI+AGAS+ QLY+ L+ Sbjct: 309 KGGVSGAKLKDISTKFICEMYNYTNKQIPIIASGGIFSGLDALEKIEAGASVCQLYSCLV 368 Query: 360 FLGPPVVVRVKRELEALLKERGFTTVTDAIGADHRR 395 F G V++KREL LL +RG+ + +AIG H + Sbjct: 369 FNGMKSAVQIKRELNHLLYQRGYYNLKEAIGRKHSK 404 >1TV5-A nrPDB Length = 443 Score = 270 bits (691), Expect = 7e-73, Method: Compositional matrix adjust. Identities = 149/409 (36%), Positives = 221/409 (54%), Gaps = 51/409 (12%) Query: 34 DHFYAEYLMPGLQRLLDPESAHRLAVRVTSLGLLPRATFQDSDMLEVKVLGHKFRNPVGI 93 + F + + + +D E H L + + +LP T DS + F NP G+ Sbjct: 38 EFFLYDIFLKFCLKYIDGEICHDLFLLLGKYNILPYDTSNDSIYACTNIKHLDFINPFGV 97 Query: 94 AAGFDKNGEAVDGLYKLGFGFVEVGSVTPQPQEGNPRPRVFRLPEDQAVINRYGFNSHGL 153 AAGFDKNG +D + KLGF F+E+G++TP+ Q GN +PR+FR E +++IN GFN+ G Sbjct: 98 AAGFDKNGVCIDSILKLGFSFIEIGTITPRGQTGNAKPRIFRDVESRSIINSCGFNNMGC 157 Query: 154 SVVEHRL---RARQQKQAQLTADGLPLGINLGKNKTSEDAAADYAEGVRTLGPLADYLVV 210 V L R RQ++ L+ +G+++GKNK + + D + +G ADY+ + Sbjct: 158 DKVTENLILFRKRQEEDKLLSKH--IVGVSIGKNKDTVNIVDDLKYCINKIGRYADYIAI 215 Query: 211 NVSSPNTAGLRSLQGKTELRHLLSKVLQERDALKGT------------------------ 246 NVSSPNT GLR Q +L++++ V +E D L+ Sbjct: 216 NVSSPNTPGLRDNQEAGKLKNIILSVKEEIDNLEKNNIMNDESTYNEDNKIVEKKNNFNK 275 Query: 247 --------------------RKPAVLVKIAPDLTAQDKEDIASVARELGIDGLIVTNTTV 286 +KP V VK+APDL + K++IA V E IDG+I++NTT Sbjct: 276 NNSHMMKDAKDNFLWFNTTKKKPLVFVKLAPDLNQEQKKEIADVLLETNIDGMIISNTTT 335 Query: 287 SRPVGLQGALRSETGGLSGKPLRDLSTQTIREMYALTQGRIPIIGVGGVSSGQDALEKIQ 346 + + ++ GG+SG L+D+ST+ I EMY T +IPII GG+ SG DALEKI+ Sbjct: 336 Q--INDIKSFENKKGGVSGAKLKDISTKFICEMYNYTNKQIPIIASGGIFSGLDALEKIE 393 Query: 347 AGASLVQLYTALIFLGPPVVVRVKRELEALLKERGFTTVTDAIGADHRR 395 AGAS+ QLY+ L+F G V++KREL LL +RG+ + +AIG H + Sbjct: 394 AGASVCQLYSCLVFNGMKSAVQIKRELNHLLYQRGYYNLKEAIGRKHSK 442 >4XQ6-A nrPDB Length = 344 Score = 234 bits (598), Expect = 4e-62, Method: Compositional matrix adjust. Identities = 143/321 (44%), Positives = 195/321 (60%), Gaps = 18/321 (5%) Query: 77 MLEVKVLGHKFRNPVGIAAGFDKNGEAVDGLYKLGFGFVEVGSVTPQPQEGNPRPRVFRL 136 +L V G +F P+G+AAGFDK+G A+ +GFG+ E+G+VT PQ GNP PR+FRL Sbjct: 39 VLASTVFGVRFPAPLGLAAGFDKDGTALSSWGAMGFGYAEIGTVTAHPQPGNPAPRLFRL 98 Query: 137 PEDQAVINRYGFNSHGLSVVEHRLRARQQKQAQLTADGLPLGINLGKNKTSE--DAAADY 194 +D+A++NR GFN+HG + RL AR + + +P+G+N+GK K + DA DY Sbjct: 99 ADDRALLNRMGFNNHGARALAIRL-ARHRPE-------IPIGVNIGKTKKTPAGDAVNDY 150 Query: 195 AEGVRTLGPLADYLVVNVSSPNTAGLRSLQGKTELRHLLSKVLQERDALKGTRKPAVLVK 254 R +GPLA YLVVNVSSPNT GLR LQ LR +LS V E T P VLVK Sbjct: 151 RASARMVGPLASYLVVNVSSPNTPGLRDLQAVESLRPILSAVRAE------TSTP-VLVK 203 Query: 255 IAPDLTAQDKEDIASVARELGIDGLIVTNTTVSRP-VGLQGALRSETGGLSGKPLRDLST 313 IAPDL+ D +DIA +A EL + G++ TNTTVSR + G R GG+SG PL + Sbjct: 204 IAPDLSDSDLDDIADLAVELDLAGIVATNTTVSRDGLTTPGVDRLGPGGISGPPLAQRAV 263 Query: 314 QTIREMYALTQGRIPIIGVGGVSSGQDALEKIQAGASLVQLYTALIFLGPPVVVRVKREL 373 Q +R +Y R+ +I VGG+ + DA E+I AGASL+Q YT I+ G + + Sbjct: 264 QVLRRLYDRVGDRLALISVGGIETADDAWERITAGASLLQGYTGFIYGGERWAKDIHEGI 323 Query: 374 EALLKERGFTTVTDAIGADHR 394 L + GF ++ +A+G+ R Sbjct: 324 ARRLHDGGFGSLHEAVGSARR 344 >1F76-A nrPDB Length = 336 Score = 228 bits (582), Expect = 3e-60, Method: Compositional matrix adjust. Identities = 141/333 (42%), Positives = 199/333 (59%), Gaps = 25/333 (7%) Query: 49 LDPESAHRLAVRV------TSLGLLPRATFQDSDMLEVKVLGHKFRNPVGIAAGFDKNGE 102 LDPE AH + T L R Q V +G F+NP+G+AAG DK+GE Sbjct: 13 LDPERAHEFTFQQLRRITGTPFEALVR---QKVPAKPVNCMGLTFKNPLGLAAGLDKDGE 69 Query: 103 AVDGLYKLGFGFVEVGSVTPQPQEGNPRPRVFRLPEDQAVINRYGFNSHGL-SVVEHRLR 161 +D L +GFG +E+G+VTP+PQ GN +PR+FRL + + +INR GFN+ G+ ++VE+ + Sbjct: 70 CIDALGAMGFGSIEIGTVTPRPQPGNDKPRLFRLVDAEGLINRMGFNNLGVDNLVENVKK 129 Query: 162 ARQQKQAQLTADGLPLGINLGKNKTS--EDAAADYAEGVRTLGPLADYLVVNVSSPNTAG 219 A DG+ LGIN+GKNK + E DY + + A Y+ +N+SSPNT G Sbjct: 130 AHY--------DGV-LGINIGKNKDTPVEQGKDDYLICMEKIYAYAGYIAINISSPNTPG 180 Query: 220 LRSLQGKTELRHLLSKVLQERDALKGTRKPAV--LVKIAPDLTAQDKEDIASVARELGID 277 LR+LQ L LL+ + +++ L+ V VKIAPDL+ ++ +A ID Sbjct: 181 LRTLQYGEALDDLLTAIKNKQNDLQAMHHKYVPIAVKIAPDLSEEELIQVADSLVRHNID 240 Query: 278 GLIVTNTTVSRPVGLQGALRS-ETGGLSGKPLRDLSTQTIREMYALTQGRIPIIGVGGVS 336 G+I TNTT+ R + +QG +TGGLSG+PL+ ST+ IR + GR+PIIGVGG+ Sbjct: 241 GVIATNTTLDRSL-VQGMKNCDQTGGLSGRPLQLKSTEIIRRLSLELNGRLPIIGVGGID 299 Query: 337 SGQDALEKIQAGASLVQLYTALIFLGPPVVVRV 369 S A EKI AGASLVQ+Y+ IF GPP++ + Sbjct: 300 SVIAAREKIAAGASLVQIYSGFIFKGPPLIKEI 332 >6B8S-A nrPDB Length = 359 Score = 218 bits (555), Expect = 4e-57, Method: Compositional matrix adjust. Identities = 136/358 (37%), Positives = 198/358 (55%), Gaps = 31/358 (8%) Query: 49 LDPESAHRLAVRVTSLGLLPRATFQDSDM----------LEVKVLGHKFRNPVGIAAGFD 98 LD E AH ++ L L +++F S + LE ++LG F NP+G+AAGFD Sbjct: 21 LDAEDAHEKVCKI--LRTLSKSSFLCSLIHSQWGYKNPKLENEILGLNFPNPLGLAAGFD 78 Query: 99 KNGEAVDGLYKLGFGFVEVGSVTPQPQEGNPRPRVFRLPEDQAVINRYGFNSHGLSVVEH 158 KN + L GFG++E G++T + Q GN RPR+FR E++++ N GFN++G +V+ Sbjct: 79 KNASMLRALIAFGFGYLEAGTLTNEAQVGNERPRLFRHIEEESLQNAMGFNNYG-AVLGA 137 Query: 159 RLRARQQKQAQLTADGLPLGINLGKNKTSEDAAA--DYAEGVRTLGPLADYLVVNVSSPN 216 R R P+GINLGKNK E A A DY + + DY N+SSPN Sbjct: 138 RSFNR------FAPYKTPIGINLGKNKHIEQAHALEDYKAVLNQCLNIGDYYTFNLSSPN 191 Query: 217 TAGLRSLQGKTELRHLLSKVLQERDALKGTRKPAVLVKIAPDLTAQDKEDIASVARELGI 276 T LR LQ K + L A + T KP + +KIAPDL D +I + A E G Sbjct: 192 TPNLRDLQNKAFVNELFCM------AKEMTHKP-LFLKIAPDLEIDDMLEIVNSAIEAGA 244 Query: 277 DGLIVTNTTVSRPVGLQGALRSETGGLSGKPLRDLSTQTIREMYALTQGRIPIIGVGGVS 336 G+I TNTT+ + + E GGLSGK L S + +E+ + ++ VGG+S Sbjct: 245 HGIIATNTTIDKSLVFA---PKEMGGLSGKCLTKKSREVFKELAKAFFNKSVLVSVGGIS 301 Query: 337 SGQDALEKIQAGASLVQLYTALIFLGPPVVVRVKRELEALLKERGFTTVTDAIGADHR 394 ++A E+I+ GASL+Q+Y+A I+ GP + + ++L LL++ GF +V +AIGAD R Sbjct: 302 DAKEAYERIKMGASLLQIYSAFIYNGPNLCQNILKDLVKLLQKDGFLSVKEAIGADLR 359 >5UE9-A nrPDB Length = 306 Score = 93.2 bits (230), Expect = 2e-19, Method: Compositional matrix adjust. Identities = 95/319 (29%), Positives = 146/319 (45%), Gaps = 29/319 (9%) Query: 78 LEVKVLGHKFRNPVGIAAGFDKNGEAVDGLYKLG-FGFVEVGSVTPQPQEGNPRPRVFRL 136 L VK+ G +NP+ A+G GE Y L G + V + T P+ GNP PRV Sbjct: 3 LSVKLPGLDLKNPIIPASGCFGFGEEYAKYYDLNKLGSIMVKATTLHPRFGNPTPRVAE- 61 Query: 137 PEDQAVINRYGFNSHGLSVVEHRLRARQQKQAQLTADGLPLGINLGKNKTSEDAAADYAE 196 ++N G + GL V+ A + LP+ N+ + ED DY Sbjct: 62 -TASGMLNAIGLQNPGLEVI----MAEKLPWLNENFPDLPIIANVAG--SEED---DYVA 111 Query: 197 GVRTLG--PLADYLVVNVSSPNTA-GLRSLQGKTELRHLLSKVLQERDALKGTRKPAVLV 253 +G P + +N+S PN G ++ ++ L K A K K + V Sbjct: 112 VCAKIGDAPNVKVIELNISCPNVKHGGQAFGTDPDVAAALVK------ACKAVSKVPLYV 165 Query: 254 KIAPDLTAQDKEDIASVARELGIDGLIVTNTTVSRPVGLQG---ALRSETGGLSGKPLRD 310 K++P++T D IA G DGL + NT + L+ L + TGGLSG ++ Sbjct: 166 KLSPNVT--DIVPIAKAVEAAGADGLTMINTLMGVRFDLKTRKPVLANITGGLSGPAIKP 223 Query: 311 LSTQTIREMYALTQGRIPIIGVGGVSSGQDALEKIQAGASLVQLYTALIFLGPPVVVRVK 370 ++ + I ++ + IPIIG+GGV S QD LE AGAS V + TA F P V ++ Sbjct: 224 VALKLIHQVAQVVD--IPIIGMGGVESAQDVLEMYMAGASAVAVGTAN-FADPFVCPKII 280 Query: 371 RELEALLKERGFTTVTDAI 389 +L ++ + G ++ + I Sbjct: 281 EKLPEVMDQYGIDSLENLI 299 >1EP3-A nrPDB Length = 311 Score = 90.9 bits (224), Expect = 9e-19, Method: Compositional matrix adjust. Identities = 96/316 (30%), Positives = 147/316 (46%), Gaps = 31/316 (9%) Query: 72 FQDSDMLEVKVLGHKFRNPVGIAAGFDKNGEAVDGLYKLG-FGFVEVGSVTPQPQEGNPR 130 +++ L VK+ G +NP+ A+G GE Y L G + V + T P+ GNP Sbjct: 1 MTENNRLSVKLPGLDLKNPIIPASGCFGFGEEYAKYYDLNKLGSIMVKATTLHPRFGNPT 60 Query: 131 PRVFRLPEDQAVINRYGFNSHGLSVV-EHRLRARQQKQAQLTADGLPLGINLGKNKTSED 189 PRV ++N G + GL V+ +L + +L P+ N+ SE+ Sbjct: 61 PRVAE--TASGMLNAIGLQNPGLEVIMTEKLPWLNENFPEL-----PIIANVAG---SEE 110 Query: 190 AAADYAEGVRTLGPLADYLVV--NVSSPNTA-GLRSLQGKTELRHLLSKVLQERDALKGT 246 A DY +G A+ + N+S PN G ++ E+ L K A K Sbjct: 111 A--DYVAVCAKIGDAANVKAIELNISCPNVKHGGQAFGTDPEVAAALVK------ACKAV 162 Query: 247 RKPAVLVKIAPDLTAQDKEDIASVARELGIDGLIVTNTTVSRPVGL---QGALRSETGGL 303 K + VK++P++T D IA G DGL + NT + L Q L + TGGL Sbjct: 163 SKVPLYVKLSPNVT--DIVPIAKAVEAAGADGLTMINTLMGVRFDLKTRQPILANITGGL 220 Query: 304 SGKPLRDLSTQTIREMYALTQGRIPIIGVGGVSSGQDALEKIQAGASLVQLYTALIFLGP 363 SG ++ ++ + I ++ IPIIG+GGV++ QD LE AGAS V + TA F P Sbjct: 221 SGPAIKPVALKLIHQVA--QDVDIPIIGMGGVANAQDVLEMYMAGASAVAVGTAN-FADP 277 Query: 364 PVVVRVKRELEALLKE 379 V ++ +L L+ + Sbjct: 278 FVCPKIIDKLPELMDQ 293 >4WZH-A nrPDB Length = 347 Score = 79.3 bits (194), Expect = 3e-15, Method: Compositional matrix adjust. Identities = 90/348 (25%), Positives = 148/348 (42%), Gaps = 47/348 (13%) Query: 65 GLLPRATF-----------QDSDMLEVKVLGHKFRNPVGIAAG-FDKNGEAVDGLYKLGF 112 GL+PR + + S L+V +LG+ F NP AAG E + + + Sbjct: 13 GLVPRGSHMASMTGGGQMGRGSMSLQVGILGNTFANPFMNAAGVMCSTEEELAAMTESTS 72 Query: 113 GFVEVGSVTPQPQEGNPRPRVFRLPEDQAVINRYGFNSHGLSVVEHRLRARQQKQAQLTA 172 G + S TP +EGNP PR + LP IN G + G AR ++ Sbjct: 73 GSLITKSCTPALREGNPAPRYYTLPLGS--INSMGLPNKGFDFYL-AYSARHHDYSRK-- 127 Query: 173 DGLPLGINLGKNKTSEDAAADYAEGVRTLGPLAD----YLVVNVSSPNTAGLRSLQGKTE 228 PL I++ E+A E + L P+A L +N+S PN G + + Sbjct: 128 ---PLFISISGFSAEENA-----EMCKRLAPVAAEKGVILELNLSCPNVPGKPQVAYDFD 179 Query: 229 -LRHLLSKVLQERDALKGTRKPAVLVKIAPDLTAQ-----DKEDIASVARELGIDGLIV- 281 +R L+ + + G + P D A+ K + +G +GL++ Sbjct: 180 AMRRYLAAISEAYPHPFGVKMPPYFDFAHFDAAAEILNQFPKVQFITCINSIG-NGLVID 238 Query: 282 --TNTTVSRPVGLQGALRSETGGLSGKPLRDLSTQTIREMYALTQGRIPIIGVGGVSSGQ 339 T + V +P + GGL G+ + + + Y G++ I G GGV +G+ Sbjct: 239 VETESVVIKP-------KQGFGGLGGRYVFPTALANVNAFYRRCPGKL-IFGCGGVYTGE 290 Query: 340 DALEKIQAGASLVQLYTALIFLGPPVVVRVKRELEALLKERGFTTVTD 387 DA + AGAS+VQ+ TAL G + R+ EL ++ ++G+ + + Sbjct: 291 DAFLHVLAGASMVQVGTALHEEGAAIFERLTAELLDVMAKKGYKALDE 338 >1JUE-A nrPDB Length = 311 Score = 79.0 bits (193), Expect = 3e-15, Method: Compositional matrix adjust. Identities = 84/329 (25%), Positives = 137/329 (41%), Gaps = 38/329 (11%) Query: 77 MLEVKVLGHKFRNPVGIAAGFD-KNGEAVDGLYKLGFGFVEVGSVTPQPQEGNPRPRVFR 135 ML KF NP A+G E ++ L G S T + +EGNP PR Sbjct: 1 MLNTTFANAKFANPFMNASGVHCMTIEDLEELKASQAGAYITKSSTLEKREGNPLPRYVD 60 Query: 136 LPEDQAVINRYGFNSHGLSVVEHRLRARQQKQAQ-----LTADGLPLGINLGKNKTSEDA 190 L + IN G + G + Q++ AQ + G+ N+ K +++ Sbjct: 61 L--ELGSINSMGLPNLGFDYYLDYVLKNQKENAQEGPIFFSIAGMSAAENIAMLKKIQES 118 Query: 191 AADYAEGVRTLGPLADYLVVNVSSPNTAGLRSLQGKTE-LRHLLSKVLQERDALKGTRKP 249 D++ G+ L N+S PN G L E LL +V G + P Sbjct: 119 --DFS-GITEL---------NLSCPNVPGKPQLAYDFEATEKLLKEVFTFFTKPLGVKLP 166 Query: 250 AVLVKIAPDLTAQ--------DKEDIASVARELGIDGLIVTNTTVSRPVGLQGALRSETG 301 + D+ A+ + S+ L ID + V +P + G Sbjct: 167 PYFDLVHFDIMAEILNQFPLTYVNSVNSIGNGLFIDP--EAESVVIKP-------KDGFG 217 Query: 302 GLSGKPLRDLSTQTIREMYALTQGRIPIIGVGGVSSGQDALEKIQAGASLVQLYTALIFL 361 G+ G ++ + +R Y + I IIG GG+ +GQDA E + GA+++Q+ TAL Sbjct: 218 GIGGAYIKPTALANVRAFYTRLKPEIQIIGTGGIETGQDAFEHLLCGATMLQIGTALHKE 277 Query: 362 GPPVVVRVKRELEALLKERGFTTVTDAIG 390 GP + R+ +ELE ++ ++G+ ++ D G Sbjct: 278 GPAIFDRIIKELEEIMNQKGYQSIADFHG 306 >5XFW-A nrPDB Length = 334 Score = 77.8 bits (190), Expect = 8e-15, Method: Compositional matrix adjust. Identities = 88/324 (27%), Positives = 138/324 (42%), Gaps = 36/324 (11%) Query: 78 LEVKVLGHKFRNPVGIAAG-FDKNGEAVDGLYKLGFGFVEVGSVTPQPQEGNPRPRVFRL 136 L+V +LGH+F NP AAG E + + + G + S T P+ GNP PR F L Sbjct: 24 LKVNILGHEFSNPFMNAAGVLCTTEEDLRRMTESESGSLIGKSCTLAPRTGNPEPRYFGL 83 Query: 137 PEDQAVINRYGFNSHGLSVVEHRLRARQQKQAQLTADGLPLGINLGKNKTSEDAAADYAE 196 P IN G + G V+ L Q PL +++ E E Sbjct: 84 P--LGSINSMGLPNLG---VDFYLSYAAQTHDYSRK---PLFLSMSGLSVEESV-----E 130 Query: 197 GVRTLGPLAD----YLVVNVSSPNTAGLRSLQGKTEL-RHLLSKVLQERDALKGTRKPAV 251 V+ L P+ L +N+S PN G + + R L KV + G + P Sbjct: 131 MVKKLVPITKEKGTILELNLSCPNVPGKPQVGYDFDTTRTYLQKVSEAYGLPFGVKMPPY 190 Query: 252 LVKIAPDLTAQDKEDIA-----SVARELGIDGLIV---TNTTVSRPVGLQGALRSETGGL 303 D+ A D + +G +GL++ T V +P + GGL Sbjct: 191 FDIAHFDMAAAVLNDFPLVKFITCVNSIG-NGLVIDPANETVVIKP-------KQGFGGL 242 Query: 304 SGKPLRDLSTQTIREMYALTQGRIPIIGVGGVSSGQDALEKIQAGASLVQLYTALIFLGP 363 GK + + + + ++ + G GGV SG++A I AGAS+VQ+ TAL GP Sbjct: 243 GGKYVLPTALANVNAFFRRCPDKL-VFGCGGVYSGEEAFLHILAGASMVQVGTALHDEGP 301 Query: 364 PVVVRVKRELEALLKERGFTTVTD 387 + R+ +EL+ ++ +G+ T+ + Sbjct: 302 IIFARLNKELQEIMTNKGYKTLDE 325 >3W7D-A nrPDB Length = 313 Score = 75.1 bits (183), Expect = 5e-14, Method: Compositional matrix adjust. Identities = 88/329 (26%), Positives = 132/329 (40%), Gaps = 44/329 (13%) Query: 77 MLEVKVLGHKFRNPVGIAAG-FDKNGEAVDGLYKLGFGFVEVGSVTPQPQEGNPRPRVFR 135 L++ +L H F NP AAG E + + G + S T P++GNP PR Sbjct: 2 CLKLNLLDHVFANPFMNAAGVLCSTEEDLRCMTASSSGALVSKSCTSAPRDGNPEPRYMA 61 Query: 136 LPEDQAVINRYGFNSHGLSVV---EHRLRARQQKQAQLTADGLPLGINLGKNKTSEDAAA 192 P IN G + G L +K L+ GL + N+ Sbjct: 62 FP--LGSINSMGLPNLGFDFYLKYASDLHDYSKKPLFLSISGLSVEENVAM--------- 110 Query: 193 DYAEGVRTLGPLAD----YLVVNVSSPNTAGLRSLQGKTE-LRHLLSKVLQERDALKGTR 247 VR L P+A L +N+S PN G + E +R L +V G Sbjct: 111 -----VRRLAPVAQEKGVLLELNLSCPNVPGKPQVAYDFEAMRTYLQQVSLAYGLPFG-- 163 Query: 248 KPAVLVKIAPDLTAQDKEDIASVARELGIDGLIVTNTTVSRPVGLQGALRSET------- 300 VK+ P + A+V E + + +V GL SE+ Sbjct: 164 -----VKMPPYFDIAHFDTAAAVLNEFPLVKFVTCVNSVGN--GLVIDAESESVVIKPKQ 216 Query: 301 --GGLSGKPLRDLSTQTIREMYALTQGRIPIIGVGGVSSGQDALEKIQAGASLVQLYTAL 358 GGL GK + + + Y ++ + G GGV SG+DA I AGAS+VQ+ TAL Sbjct: 217 GFGGLGGKYILPTALANVNAFYRRCPDKL-VFGCGGVYSGEDAFLHILAGASMVQVGTAL 275 Query: 359 IFLGPPVVVRVKRELEALLKERGFTTVTD 387 GP + R++ EL ++ +G+ T+ + Sbjct: 276 QEEGPGIFTRLEDELLEIMARKGYRTLEE 304 >3GZ3-A nrPDB Length = 354 Score = 72.8 bits (177), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 88/324 (27%), Positives = 139/324 (42%), Gaps = 36/324 (11%) Query: 78 LEVKVLGHKFRNPVGIAAG-FDKNGEAVDGLYKLGFGFVEVGSVTPQPQEGNPRPRVFRL 136 L+V +L + F NP AAG E + + + G + S TP +EGNP PR L Sbjct: 37 LQVNLLNNTFANPFMNAAGVMCTTTEELVAMTESASGSLVSKSCTPALREGNPTPRYQAL 96 Query: 137 PEDQAVINRYGFNSHGLSVVEHRLRARQQ-----KQAQLTADGLPLGINLGKNKTSEDAA 191 P IN G ++G + A +Q K L+ GL + N+ K AA Sbjct: 97 PLGS--INSMGLPNNGFDF--YLAYAAEQHDYGKKPLFLSMSGLSMRENVEMCK--RLAA 150 Query: 192 ADYAEGVRTLGPLADYLVVNVSSPNTAGLRSLQGKTE-LRHLLSKVLQERDALKGTRKPA 250 +GV L +N+S PN G + + +R L+ V + G + P Sbjct: 151 VATEKGV--------ILELNLSCPNVPGKPQVAYDFDAMRQCLTAVSEVYPHSFGVKMPP 202 Query: 251 VLVKIAPDLTAQDKEDIASVARELGID----GLIV---TNTTVSRPVGLQGALRSETGGL 303 D A+ + V I+ GL++ T + V +P + GGL Sbjct: 203 YFDFAHFDAAAEILNEFPKVQFITCINSIGNGLVIDAETESVVIKP-------KQGFGGL 255 Query: 304 SGKPLRDLSTQTIREMYALTQGRIPIIGVGGVSSGQDALEKIQAGASLVQLYTALIFLGP 363 G+ + + I Y G++ I G GGV +G+DA + AGAS+VQ+ TAL GP Sbjct: 256 GGRYVLPTALANINAFYRRCPGKL-IFGCGGVYTGEDAFLHVLAGASMVQVGTALQEEGP 314 Query: 364 PVVVRVKRELEALLKERGFTTVTD 387 + R+ EL ++ ++ + T+ + Sbjct: 315 SIFERLTSELLGVMAKKRYQTLDE 338 >3OIX-A nrPDB Length = 345 Score = 71.2 bits (173), Expect = 8e-13, Method: Compositional matrix adjust. Identities = 55/183 (30%), Positives = 89/183 (48%), Gaps = 12/183 (6%) Query: 210 VNVSSPNTAGLRSLQGKTELR-HLLSKVLQERDALKGTRKPAVLVKIAPDLTAQ--DKED 266 +N+S PN G + E +LS+V G + P + D A +K Sbjct: 161 LNLSCPNVPGKPQIAYDFETTDQILSEVFTYFTKPLGIKLPPYFDIVHFDQAAAIFNKYP 220 Query: 267 IASVARELGI-DGLIVTN-TTVSRPVGLQGALRSETGGLSGKPLRDLSTQTIREMYALTQ 324 + V I +GL++ + T V +P ++ GG+ G ++ + + Y Sbjct: 221 LTFVNCINSIGNGLVIEDETVVIKP-------KNGFGGIGGDYVKPTALANVHAFYKRLN 273 Query: 325 GRIPIIGVGGVSSGQDALEKIQAGASLVQLYTALIFLGPPVVVRVKRELEALLKERGFTT 384 I IIG GGV +G+DA E I GAS+VQ+ TAL GP + R+ +EL+A++ E+G+ T Sbjct: 274 PSIQIIGTGGVKTGRDAFEHILCGASMVQIGTALHQEGPQIFKRITKELKAIMTEKGYET 333 Query: 385 VTD 387 + D Sbjct: 334 LED 336 >5ZBN-A nrPDB Length = 371 Score = 36.2 bits (82), Expect = 0.022, Method: Compositional matrix adjust. Identities = 24/68 (35%), Positives = 34/68 (50%), Gaps = 7/68 (10%) Query: 312 STQTIREMYALTQGRIPIIGVGGVSSGQDALEKIQAGASLVQLYTALIFLGPPVVVRVKR 371 + + E+ QGRIP+ GGV G D + + GAS IF+G PVV + Sbjct: 266 TIMALEEVVKAAQGRIPVFLDGGVRRGTDVFKALALGAS-------GIFIGRPVVFSLAA 318 Query: 372 ELEALLKE 379 E EA +K+ Sbjct: 319 EGEAGIKK 326 >1AL8-A nrPDB Length = 359 Score = 35.8 bits (81), Expect = 0.036, Method: Compositional matrix adjust. Identities = 34/126 (26%), Positives = 52/126 (41%), Gaps = 23/126 (18%) Query: 270 VARELGIDGLIVTNTTVSRPVGLQGALRSETGGL-----------SGKPLRDL-----ST 313 + R L + T S P+ ++G + +E L S R L + Sbjct: 207 IDRSLSWKDVAWLQTITSLPILVKGVITAEDARLAVQHGAAGIIVSNHGARQLDYVPATI 266 Query: 314 QTIREMYALTQGRIPIIGVGGVSSGQDALEKIQAGASLVQLYTALIFLGPPVVVRVKREL 373 + E+ QGRIP+ GGV G D + + GA A +F+G PVV + E Sbjct: 267 MALEEVVKAAQGRIPVFLDGGVRRGTDVFKALALGA-------AGVFIGRPVVFSLAAEG 319 Query: 374 EALLKE 379 EA +K+ Sbjct: 320 EAGVKK 325 >3SGZ-A nrPDB Length = 352 Score = 35.0 bits (79), Expect = 0.057, Method: Compositional matrix adjust. Identities = 41/152 (26%), Positives = 65/152 (42%), Gaps = 40/152 (26%) Query: 246 TRKPAVLVKIAPDLTAQDKEDIASVARELGIDGLIVTNTTVSRPVGLQGALRSETGGLSG 305 TR P +L I LT +D E +A + + G++V+N G Sbjct: 216 TRLPIILKGI---LTKEDAE----LAMKHNVQGIVVSNH-------------------GG 249 Query: 306 KPLRDLSTQ--TIREMYALTQGRIPIIGVGGVSSGQDALEKIQAGASLVQLYTALIFLGP 363 + L ++S +RE+ A +G+I + GGV +G D L+ + GA IFLG Sbjct: 250 RQLDEVSASIDALREVVAAVKGKIEVYMDGGVRTGTDVLKALALGAR-------CIFLGR 302 Query: 364 PVVVRVKRELEALLKERGFTTVTDAIGADHRR 395 P++ + A E G V D + A+ R Sbjct: 303 PILWGL-----ACKGEDGVKEVLDILTAELHR 329 >2CDH-0 nrPDB Length = 226 Score = 34.7 bits (78), Expect = 0.066, Method: Compositional matrix adjust. Identities = 23/68 (33%), Positives = 34/68 (50%), Gaps = 7/68 (10%) Query: 312 STQTIREMYALTQGRIPIIGVGGVSSGQDALEKIQAGASLVQLYTALIFLGPPVVVRVKR 371 + + E+ QGRIP+ GGV G D + + GA A +F+G PVV + Sbjct: 149 TIMALEEVVKAAQGRIPVFLDGGVRRGTDVFKALALGA-------AGVFIGRPVVFSLAA 201 Query: 372 ELEALLKE 379 E EA +K+ Sbjct: 202 EGEAGVKK 209 >2RDM-A nrPDB Length = 132 Score = 31.2 bits (69), Expect = 0.77, Method: Compositional matrix adjust. Identities = 18/46 (39%), Positives = 28/46 (60%), Gaps = 3/46 (6%) Query: 332 VGGVSSGQDALEKIQAGASLVQLYTALIFLGPP---VVVRVKRELE 374 V VSSG A+E +++GA++ + T + F PP V RV RE++ Sbjct: 32 VTAVSSGAKAIEMLKSGAAIDGVVTDIRFCQPPDGWQVARVAREID 77 >5Y2D-A nrPDB Length = 465 Score = 30.8 bits (68), Expect = 1.1, Method: Compositional matrix adjust. Identities = 31/119 (26%), Positives = 49/119 (41%), Gaps = 9/119 (7%) Query: 1 MAWRQLRKRALDAVIILGGGGLLFTSYLTATGDDHFYAEYLMPGLQR-----LLDPESAH 55 M ++ +RAL + +I+ G + T+ G D + +PG + L+ +S Sbjct: 79 MIPKERMERALGSGVIISKDGYIVTNNHVIDGADKI--KVTIPGSNKEYSATLVGTDSES 136 Query: 56 RLAVRVTSLGLLPRATFQDSDMLEVKVLGHKFRNPVGIAAGFDKNGEAVDGLYKLGFGF 114 LAV + LP F DS+ + V L NP G+ + V L K G G Sbjct: 137 DLAVIRITKDNLPTIKFSDSNDISVGDLVFAIGNPFGVGESVTQG--IVSALNKSGIGI 193 >5Y28-A nrPDB Length = 357 Score = 30.4 bits (67), Expect = 1.3, Method: Compositional matrix adjust. Identities = 31/119 (26%), Positives = 49/119 (41%), Gaps = 9/119 (7%) Query: 1 MAWRQLRKRALDAVIILGGGGLLFTSYLTATGDDHFYAEYLMPGLQR-----LLDPESAH 55 M ++ +RAL + +I+ G + T+ G D + +PG + L+ +S Sbjct: 79 MIPKERMERALGSGVIISKDGYIVTNNHVIDGADKI--KVTIPGSNKEYSATLVGTDSES 136 Query: 56 RLAVRVTSLGLLPRATFQDSDMLEVKVLGHKFRNPVGIAAGFDKNGEAVDGLYKLGFGF 114 LAV + LP F DS+ + V L NP G+ + V L K G G Sbjct: 137 DLAVIRITKDNLPTIKFSDSNDISVGDLVFAIGNPFGVGESVTQG--IVSALNKSGIGI 193 >3PUD-A nrPDB Length = 291 Score = 30.4 bits (67), Expect = 1.5, Method: Compositional matrix adjust. Identities = 15/39 (38%), Positives = 23/39 (58%) Query: 313 TQTIREMYALTQGRIPIIGVGGVSSGQDALEKIQAGASL 351 TQ I+E+ + RIPII G +S ++A+E +A L Sbjct: 57 TQVIKEIIRVANKRIPIIAGTGANSTREAIELTKAAKDL 95 >4Q4K-A nrPDB Length = 357 Score = 30.0 bits (66), Expect = 1.7, Method: Compositional matrix adjust. Identities = 12/39 (30%), Positives = 22/39 (56%) Query: 323 TQGRIPIIGVGGVSSGQDALEKIQAGASLVQLYTALIFL 361 +G +P++ GG+ G+ ++ GAS VQ+ TA + Sbjct: 207 ARGSLPVVAAGGIMDGRGIRAALELGASAVQMGTAFVLC 245 >2Z6J-A nrPDB Length = 332 Score = 29.6 bits (65), Expect = 2.2, Method: Compositional matrix adjust. Identities = 22/61 (36%), Positives = 30/61 (49%), Gaps = 5/61 (8%) Query: 299 ETGGLSGKPLRDLSTQTIREMYALTQGRIPIIGVGGVSSGQDALEKIQAGASLVQLYTAL 358 E GG GK L+T T+ A T IP+I GG++ G+ A GA VQ+ T Sbjct: 140 EAGGHIGK----LTTMTLVRQVA-TAISIPVIAAGGIADGEGAAAGFMLGAEAVQVGTRF 194 Query: 359 I 359 + Sbjct: 195 V 195 >2RDU-A nrPDB Length = 387 Score = 29.6 bits (65), Expect = 2.7, Method: Compositional matrix adjust. Identities = 24/78 (30%), Positives = 35/78 (44%), Gaps = 12/78 (15%) Query: 291 GLQGALRSETGG--LSGKPLRDLSTQTIREMYALTQGRIPIIGVGGVSSGQDALEKIQAG 348 GL G L S G L G P + + E+ +G++ + GGV G D L+ + G Sbjct: 268 GLNGILVSNHGARQLDGVPA---TIDVLPEIVEAVEGKVEVFLDGGVRKGTDVLKALALG 324 Query: 349 ASLVQLYTALIFLGPPVV 366 A V F+G P+V Sbjct: 325 AKAV-------FVGRPIV 335 >3L5A-A nrPDB Length = 419 Score = 29.3 bits (64), Expect = 2.9, Method: Compositional matrix adjust. Identities = 12/28 (42%), Positives = 19/28 (67%) Query: 319 MYALTQGRIPIIGVGGVSSGQDALEKIQ 346 +Y GRIP+I GG++S + AL+ +Q Sbjct: 311 VYEHLAGRIPLIASGGINSPESALDALQ 338 >3FI9-A nrPDB Length = 343 Score = 29.3 bits (64), Expect = 3.4, Method: Compositional matrix adjust. Identities = 28/91 (30%), Positives = 45/91 (49%), Gaps = 11/91 (12%) Query: 268 ASVARELGIDGLIVTNTTVSRPVGLQGALRSETGGLSGKPLRDL--STQTIREMYA---- 321 + +A+ GI +VTNT G Q A+ + T ++G PL DL + + E +A Sbjct: 160 SELAKHFGIKQSLVTNTRTYGGHGEQMAVFASTAKVNGTPLTDLIGTDKLTNEQWAELKQ 219 Query: 322 -LTQGRIPIIGVGGVSSGQD----ALEKIQA 347 + +G II + G SS Q ++E I+A Sbjct: 220 RVVKGGANIIKLRGRSSFQSPSYVSIEMIRA 250 >3EBB-A nrPDB Length = 304 Score = 29.3 bits (64), Expect = 3.5, Method: Compositional matrix adjust. Identities = 19/77 (24%), Positives = 39/77 (50%), Gaps = 4/77 (5%) Query: 221 RSLQGKTELRHLLSKVLQERDALKGTRKPAVLVKIAPDLTAQDKEDIASVARELGIDGLI 280 +++GK + L+S +L+ L+ T + +LV + ++ D + +A+ LG+D I Sbjct: 226 HNIEGKAQCLSLISTILEVVQDLEATFR--LLVALGTLIS--DDSNAVQLAKSLGVDSQI 281 Query: 281 VTNTTVSRPVGLQGALR 297 ++VS P + R Sbjct: 282 KKYSSVSEPAKVSECCR 298 >6DX9-A nrPDB Length = 405 Score = 28.9 bits (63), Expect = 4.6, Method: Compositional matrix adjust. Identities = 32/109 (29%), Positives = 47/109 (43%), Gaps = 15/109 (13%) Query: 81 KVLGHKFRNPVGIAAGFDKNGEAVDGLYKLG--FGFVEVG--SVTPQPQEGNP-RPRVFR 135 KVL FR + FD++G A D + F G ++ Q +E P R Sbjct: 286 KVLNDAFR------SAFDESGNAEDRPASVNDIFWIAHPGGPAILDQVEEKMKLAPEKMR 339 Query: 136 LPEDQAVINRYGFNSHG--LSVVEHRLRARQQKQAQLTADGLPLGINLG 182 D V++ YG S L +++H R Q + Q T +GL G+ LG Sbjct: 340 ATRD--VLSEYGNMSSACVLFIMDHMRRMSAQNKLQTTGEGLDWGVLLG 386 >3EUH-C nrPDB Length = 234 Score = 28.5 bits (62), Expect = 5.3, Method: Compositional matrix adjust. Identities = 26/89 (29%), Positives = 40/89 (44%), Gaps = 11/89 (12%) Query: 24 FTSYLTATGDDHFYAEYLMPGLQRLLDPESAHRLAVRVTSLGLLPRATFQDSDMLEVKVL 83 F YL + FYA Y ++ + PE L R T+L +PR+ + DM+ K+L Sbjct: 50 FQEYL-----EEFYARY---NVELIRAPEGFFYLRPRSTTL--IPRSVLSELDMMVGKIL 99 Query: 84 GHKFRNPVGIA-AGFDKNGEAVDGLYKLG 111 + + +P +A G E D L L Sbjct: 100 CYLYLSPERLANEGIFTQQELYDELLTLA 128 >4PE8-A nrPDB Length = 260 Score = 28.5 bits (62), Expect = 5.6, Method: Compositional matrix adjust. Identities = 12/44 (27%), Positives = 24/44 (54%) Query: 261 AQDKEDIASVARELGIDGLIVTNTTVSRPVGLQGALRSETGGLS 304 A+D++D+ + A + G++GL++T T + Q R + S Sbjct: 14 AKDRDDVVACAFDAGVNGLLITGTNLRESQQAQKLARQYSSCWS 57 >4N6F-A nrPDB Length = 256 Score = 28.1 bits (61), Expect = 7.9, Method: Compositional matrix adjust. Identities = 16/44 (36%), Positives = 26/44 (59%), Gaps = 2/44 (4%) Query: 316 IREMYALTQGRIPIIGVGGVSSGQDALEKIQAGASLVQLYTALI 359 IRE+ + Q IP++ GG+ S + E ++ GAS + TAL+ Sbjct: 180 IREL--IEQIGIPVVVEGGIGSARHVAEAMELGASATLVNTALV 221 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 3U2O-A nrPDB 554 e-158 1UUO-A nrPDB 508 e-144 6I4B-A nrPDB 450 e-127 1TV5-A nrPDB 420 e-118 6B8S-A nrPDB 349 1e-96 1F76-A nrPDB 348 3e-96 4WZH-A nrPDB 338 2e-93 3W7D-A nrPDB 333 9e-92 3GZ3-A nrPDB 332 2e-91 5XFW-A nrPDB 331 3e-91 4XQ6-A nrPDB 327 4e-90 1JUE-A nrPDB 313 6e-86 5UE9-A nrPDB 290 9e-79 3OIX-A nrPDB 289 1e-78 1EP3-A nrPDB 285 3e-77 Sequences not found previously or not previously below threshold: 2J6X-A nrPDB 43 2e-04 5LSM-A nrPDB 43 2e-04 2Z6J-A nrPDB 42 5e-04 5ZBN-A nrPDB 40 0.002 1MZH-A nrPDB 39 0.003 1AL8-A nrPDB 39 0.003 4Q4K-A nrPDB 39 0.004 3UOG-A nrPDB 38 0.006 2ZRW-A nrPDB 37 0.019 4MM1-A nrPDB 35 0.036 3SGZ-A nrPDB 35 0.037 6HUL-A nrPDB 35 0.045 3T8S-A nrPDB 35 0.062 1N4K-A nrPDB 35 0.062 1YPF-A nrPDB 35 0.064 4XBS-A nrPDB 35 0.068 2CDH-0 nrPDB 34 0.086 4JEJ-A nrPDB 34 0.15 2RDU-A nrPDB 34 0.15 6C9R-A nrPDB 33 0.19 1SZG-A nrPDB 33 0.26 3L5A-A nrPDB 33 0.27 4EVZ-A nrPDB 32 0.36 1JCN-A nrPDB 32 0.37 4J9J-A nrPDB 32 0.38 4DGS-A nrPDB 32 0.40 1QCW-A nrPDB 32 0.43 5GVH-A nrPDB 32 0.44 5D2Y-A nrPDB 32 0.55 3PZL-A nrPDB 32 0.56 4IQL-A nrPDB 31 0.74 1EEP-A nrPDB 31 0.74 3IPM-H nrPDB 31 0.79 3O15-A nrPDB 31 0.81 1VH7-A nrPDB 31 0.85 4JDY-A nrPDB 31 0.92 4LC4-A nrPDB 31 1.0 1H5Y-A nrPDB 31 1.0 6HYE-A nrPDB 30 1.2 4FXS-A nrPDB 30 1.2 1KA9-F nrPDB 30 1.3 4FEZ-A nrPDB 30 1.4 2PKQ-O nrPDB 30 1.4 5DBT-A nrPDB 30 1.6 1UB3-A nrPDB 30 1.6 3TDN-A nrPDB 30 2.1 3TDM-A nrPDB 30 2.1 3DH7-A nrPDB 30 2.1 6I0M-A nrPDB 30 2.2 2ZBT-A nrPDB 30 2.2 2ISS-A nrPDB 30 2.2 1YDN-A nrPDB 30 2.2 2NV2-A nrPDB 30 2.3 5UPU-A nrPDB 30 2.4 5MHL-A nrPDB 30 2.5 5J5Z-A nrPDB 30 2.5 6NKE-A nrPDB 29 2.7 1P0K-A nrPDB 29 2.8 4N6F-A nrPDB 29 2.9 3NDO-A nrPDB 29 3.0 2W6R-A nrPDB 29 3.1 4FIQ-A nrPDB 29 3.1 5Z9Y-A nrPDB 29 3.3 3SR7-A nrPDB 29 3.4 4PFI-A nrPDB 29 3.6 3FFS-A nrPDB 29 4.0 1PFK-A nrPDB 29 4.0 5LNT-A nrPDB 29 4.1 3R12-A nrPDB 29 4.6 4QJ1-A nrPDB 29 4.7 3TSB-A nrPDB 29 4.8 3PUD-A nrPDB 29 5.0 4MJM-A nrPDB 29 5.1 4WY0-A nrPDB 29 5.6 1HG3-A nrPDB 28 5.9 4BI9-A nrPDB 28 6.0 1VHN-A nrPDB 28 6.1 4QCC-A nrPDB 28 6.2 1VRD-A nrPDB 28 6.2 2V81-A nrPDB 28 6.9 5LNS-A nrPDB 28 7.0 1RPX-A nrPDB 28 7.9 4PXO-A nrPDB 28 9.2 >3U2O-A nrPDB Length = 395 Score = 554 bits (1427), Expect = e-158, Method: Composition-based stats. Identities = 350/395 (88%), Positives = 369/395 (93%) Query: 1 MAWRQLRKRALDAVIILGGGGLLFTSYLTATGDDHFYAEYLMPGLQRLLDPESAHRLAVR 60 MAWR L+KRA DAVIILGGGGLLF SYL ATGD+ FYAE+LMP LQ LLDPESAHRLAVR Sbjct: 1 MAWRHLKKRAQDAVIILGGGGLLFASYLMATGDERFYAEHLMPTLQGLLDPESAHRLAVR 60 Query: 61 VTSLGLLPRATFQDSDMLEVKVLGHKFRNPVGIAAGFDKNGEAVDGLYKLGFGFVEVGSV 120 TSLGLLPRA FQDSDMLEV+VLGHKFRNPVGIAAGFDK+GEAVDGLYK+GFGFVE+GSV Sbjct: 61 FTSLGLLPRARFQDSDMLEVRVLGHKFRNPVGIAAGFDKHGEAVDGLYKMGFGFVEIGSV 120 Query: 121 TPQPQEGNPRPRVFRLPEDQAVINRYGFNSHGLSVVEHRLRARQQKQAQLTADGLPLGIN 180 TP+PQEGNPRPRVFRLPEDQAVINRYGFNSHGLSVVEHRLRARQQKQA+LT DGLPLG+N Sbjct: 121 TPKPQEGNPRPRVFRLPEDQAVINRYGFNSHGLSVVEHRLRARQQKQAKLTEDGLPLGVN 180 Query: 181 LGKNKTSEDAAADYAEGVRTLGPLADYLVVNVSSPNTAGLRSLQGKTELRHLLSKVLQER 240 LGKNKTS DAA DYAEGVR LGPLADYLVVNVSSPNTAGLRSLQGK ELR LL+KVLQER Sbjct: 181 LGKNKTSVDAAEDYAEGVRVLGPLADYLVVNVSSPNTAGLRSLQGKAELRRLLTKVLQER 240 Query: 241 DALKGTRKPAVLVKIAPDLTAQDKEDIASVARELGIDGLIVTNTTVSRPVGLQGALRSET 300 D L+ +PAVLVKIAPDLT+QDKEDIASV +ELGIDGLIVTNTTVSRP GLQGALRSET Sbjct: 241 DGLRRVHRPAVLVKIAPDLTSQDKEDIASVVKELGIDGLIVTNTTVSRPAGLQGALRSET 300 Query: 301 GGLSGKPLRDLSTQTIREMYALTQGRIPIIGVGGVSSGQDALEKIQAGASLVQLYTALIF 360 GGLSGKPLRDLSTQTIREMYALTQGR+PIIGVGGVSSGQDALEKI+AGASLVQLYTAL F Sbjct: 301 GGLSGKPLRDLSTQTIREMYALTQGRVPIIGVGGVSSGQDALEKIRAGASLVQLYTALTF 360 Query: 361 LGPPVVVRVKRELEALLKERGFTTVTDAIGADHRR 395 GPPVV +VKRELEALLKE+GF VTDAIGADHRR Sbjct: 361 WGPPVVGKVKRELEALLKEQGFGGVTDAIGADHRR 395 >1UUO-A nrPDB Length = 372 Score = 508 bits (1308), Expect = e-144, Method: Composition-based stats. Identities = 366/366 (100%), Positives = 366/366 (100%) Query: 30 ATGDDHFYAEYLMPGLQRLLDPESAHRLAVRVTSLGLLPRATFQDSDMLEVKVLGHKFRN 89 ATGDDHFYAEYLMPGLQRLLDPESAHRLAVRVTSLGLLPRATFQDSDMLEVKVLGHKFRN Sbjct: 7 ATGDDHFYAEYLMPGLQRLLDPESAHRLAVRVTSLGLLPRATFQDSDMLEVKVLGHKFRN 66 Query: 90 PVGIAAGFDKNGEAVDGLYKLGFGFVEVGSVTPQPQEGNPRPRVFRLPEDQAVINRYGFN 149 PVGIAAGFDKNGEAVDGLYKLGFGFVEVGSVTPQPQEGNPRPRVFRLPEDQAVINRYGFN Sbjct: 67 PVGIAAGFDKNGEAVDGLYKLGFGFVEVGSVTPQPQEGNPRPRVFRLPEDQAVINRYGFN 126 Query: 150 SHGLSVVEHRLRARQQKQAQLTADGLPLGINLGKNKTSEDAAADYAEGVRTLGPLADYLV 209 SHGLSVVEHRLRARQQKQAQLTADGLPLGINLGKNKTSEDAAADYAEGVRTLGPLADYLV Sbjct: 127 SHGLSVVEHRLRARQQKQAQLTADGLPLGINLGKNKTSEDAAADYAEGVRTLGPLADYLV 186 Query: 210 VNVSSPNTAGLRSLQGKTELRHLLSKVLQERDALKGTRKPAVLVKIAPDLTAQDKEDIAS 269 VNVSSPNTAGLRSLQGKTELRHLLSKVLQERDALKGTRKPAVLVKIAPDLTAQDKEDIAS Sbjct: 187 VNVSSPNTAGLRSLQGKTELRHLLSKVLQERDALKGTRKPAVLVKIAPDLTAQDKEDIAS 246 Query: 270 VARELGIDGLIVTNTTVSRPVGLQGALRSETGGLSGKPLRDLSTQTIREMYALTQGRIPI 329 VARELGIDGLIVTNTTVSRPVGLQGALRSETGGLSGKPLRDLSTQTIREMYALTQGRIPI Sbjct: 247 VARELGIDGLIVTNTTVSRPVGLQGALRSETGGLSGKPLRDLSTQTIREMYALTQGRIPI 306 Query: 330 IGVGGVSSGQDALEKIQAGASLVQLYTALIFLGPPVVVRVKRELEALLKERGFTTVTDAI 389 IGVGGVSSGQDALEKIQAGASLVQLYTALIFLGPPVVVRVKRELEALLKERGFTTVTDAI Sbjct: 307 IGVGGVSSGQDALEKIQAGASLVQLYTALIFLGPPVVVRVKRELEALLKERGFTTVTDAI 366 Query: 390 GADHRR 395 GADHRR Sbjct: 367 GADHRR 372 >6I4B-A nrPDB Length = 405 Score = 450 bits (1158), Expect = e-127, Method: Composition-based stats. Identities = 154/396 (38%), Positives = 227/396 (57%), Gaps = 21/396 (5%) Query: 17 LGGGGLLFTSYLTATGDDHFYAEYLMPGLQRLLDPESAHRLAVRVTSLGLLPRATFQDSD 76 LG L F S + + F + + + +D E H L + + +LP T DS Sbjct: 13 LGTENLYFQSMFESYNPEFFLYDIFLKFCLKYIDGEICHDLFLLLGKYNILPYDTSNDSI 72 Query: 77 MLEVKVLGHKFRNPVGIAAGFDKNGEAVDGLYKLGFGFVEVGSVTPQPQEGNPRPRVFRL 136 + F NP G+AAGFDKNG +D + KLGF F+E+G++TP+ Q GN +PR+FR Sbjct: 73 YACTNIKHLDFINPFGVAAGFDKNGVCIDSILKLGFSFIEIGTITPRGQTGNAKPRIFRD 132 Query: 137 PEDQAVINRYGFNSHGLSVVEHRL---RARQQKQAQLTADGLPLGINLGKNKTSEDAAAD 193 E +++IN GFN+ G V L R RQ++ L+ +G+++GKNK + + D Sbjct: 133 VESRSIINSCGFNNMGCDKVTENLILFRKRQEEDKLLSKH--IVGVSIGKNKDTVNIVDD 190 Query: 194 YAEGVRTLGPLADYLVVNVSSPNTAGLRSLQGKTELRHLLSKVLQERDALKGT------- 246 + +G ADY+ +NVSSPNT GLR Q +L++++ V +E D L+ Sbjct: 191 LKYCINKIGRYADYIAINVSSPNTPGLRDNQEAGKLKNIILSVKEEIDNLEKNNIMNDEF 250 Query: 247 -------RKPAVLVKIAPDLTAQDKEDIASVARELGIDGLIVTNTTVSRPVGLQGALRSE 299 +KP V VK+APDL + K++IA V E IDG+I++NTT + + ++ Sbjct: 251 LWFNTTKKKPLVFVKLAPDLNQEQKKEIADVLLETNIDGMIISNTTTQ--INDIKSFENK 308 Query: 300 TGGLSGKPLRDLSTQTIREMYALTQGRIPIIGVGGVSSGQDALEKIQAGASLVQLYTALI 359 GG+SG L+D+ST+ I EMY T +IPII GG+ SG DALEKI+AGAS+ QLY+ L+ Sbjct: 309 KGGVSGAKLKDISTKFICEMYNYTNKQIPIIASGGIFSGLDALEKIEAGASVCQLYSCLV 368 Query: 360 FLGPPVVVRVKRELEALLKERGFTTVTDAIGADHRR 395 F G V++KREL LL +RG+ + +AIG H + Sbjct: 369 FNGMKSAVQIKRELNHLLYQRGYYNLKEAIGRKHSK 404 >1TV5-A nrPDB Length = 443 Score = 420 bits (1079), Expect = e-118, Method: Composition-based stats. Identities = 149/415 (35%), Positives = 222/415 (53%), Gaps = 51/415 (12%) Query: 28 LTATGDDHFYAEYLMPGLQRLLDPESAHRLAVRVTSLGLLPRATFQDSDMLEVKVLGHKF 87 + + F + + + +D E H L + + +LP T DS + F Sbjct: 32 FESYNPEFFLYDIFLKFCLKYIDGEICHDLFLLLGKYNILPYDTSNDSIYACTNIKHLDF 91 Query: 88 RNPVGIAAGFDKNGEAVDGLYKLGFGFVEVGSVTPQPQEGNPRPRVFRLPEDQAVINRYG 147 NP G+AAGFDKNG +D + KLGF F+E+G++TP+ Q GN +PR+FR E +++IN G Sbjct: 92 INPFGVAAGFDKNGVCIDSILKLGFSFIEIGTITPRGQTGNAKPRIFRDVESRSIINSCG 151 Query: 148 FNSHGLSVVEHRL---RARQQKQAQLTADGLPLGINLGKNKTSEDAAADYAEGVRTLGPL 204 FN+ G V L R RQ++ L+ +G+++GKNK + + D + +G Sbjct: 152 FNNMGCDKVTENLILFRKRQEEDKLLSKH--IVGVSIGKNKDTVNIVDDLKYCINKIGRY 209 Query: 205 ADYLVVNVSSPNTAGLRSLQGKTELRHLLSKVLQERDALKGT------------------ 246 ADY+ +NVSSPNT GLR Q +L++++ V +E D L+ Sbjct: 210 ADYIAINVSSPNTPGLRDNQEAGKLKNIILSVKEEIDNLEKNNIMNDESTYNEDNKIVEK 269 Query: 247 --------------------------RKPAVLVKIAPDLTAQDKEDIASVARELGIDGLI 280 +KP V VK+APDL + K++IA V E IDG+I Sbjct: 270 KNNFNKNNSHMMKDAKDNFLWFNTTKKKPLVFVKLAPDLNQEQKKEIADVLLETNIDGMI 329 Query: 281 VTNTTVSRPVGLQGALRSETGGLSGKPLRDLSTQTIREMYALTQGRIPIIGVGGVSSGQD 340 ++NTT + + ++ GG+SG L+D+ST+ I EMY T +IPII GG+ SG D Sbjct: 330 ISNTTTQ--INDIKSFENKKGGVSGAKLKDISTKFICEMYNYTNKQIPIIASGGIFSGLD 387 Query: 341 ALEKIQAGASLVQLYTALIFLGPPVVVRVKRELEALLKERGFTTVTDAIGADHRR 395 ALEKI+AGAS+ QLY+ L+F G V++KREL LL +RG+ + +AIG H + Sbjct: 388 ALEKIEAGASVCQLYSCLVFNGMKSAVQIKRELNHLLYQRGYYNLKEAIGRKHSK 442 >6B8S-A nrPDB Length = 359 Score = 349 bits (896), Expect = 1e-96, Method: Composition-based stats. Identities = 134/369 (36%), Positives = 199/369 (53%), Gaps = 34/369 (9%) Query: 41 LMPGLQRLL---DPESAHRLAVRVTSLGLLPRATFQDSDM----------LEVKVLGHKF 87 L P +++ L D E AH ++ L L +++F S + LE ++LG F Sbjct: 10 LYPLVKKYLFSLDAEDAHEKVCKI--LRTLSKSSFLCSLIHSQWGYKNPKLENEILGLNF 67 Query: 88 RNPVGIAAGFDKNGEAVDGLYKLGFGFVEVGSVTPQPQEGNPRPRVFRLPEDQAVINRYG 147 NP+G+AAGFDKN + L GFG++E G++T + Q GN RPR+FR E++++ N G Sbjct: 68 PNPLGLAAGFDKNASMLRALIAFGFGYLEAGTLTNEAQVGNERPRLFRHIEEESLQNAMG 127 Query: 148 FNSHGLSVVEHRLRARQQKQAQLTADGLPLGINLGKNKTSEDAAA--DYAEGVRTLGPLA 205 FN++G +V+ R R P+GINLGKNK E A A DY + + Sbjct: 128 FNNYG-AVLGARSFNR------FAPYKTPIGINLGKNKHIEQAHALEDYKAVLNQCLNIG 180 Query: 206 DYLVVNVSSPNTAGLRSLQGKTELRHLLSKVLQERDALKGTRKPAVLVKIAPDLTAQDKE 265 DY N+SSPNT LR LQ K + L + + +KIAPDL D Sbjct: 181 DYYTFNLSSPNTPNLRDLQNKAFVNELFCMAKE-------MTHKPLFLKIAPDLEIDDML 233 Query: 266 DIASVARELGIDGLIVTNTTVSRPVGLQGALRSETGGLSGKPLRDLSTQTIREMYALTQG 325 +I + A E G G+I TNTT+ + + E GGLSGK L S + +E+ Sbjct: 234 EIVNSAIEAGAHGIIATNTTIDKSLVFA---PKEMGGLSGKCLTKKSREVFKELAKAFFN 290 Query: 326 RIPIIGVGGVSSGQDALEKIQAGASLVQLYTALIFLGPPVVVRVKRELEALLKERGFTTV 385 + ++ VGG+S ++A E+I+ GASL+Q+Y+A I+ GP + + ++L LL++ GF +V Sbjct: 291 KSVLVSVGGISDAKEAYERIKMGASLLQIYSAFIYNGPNLCQNILKDLVKLLQKDGFLSV 350 Query: 386 TDAIGADHR 394 +AIGAD R Sbjct: 351 KEAIGADLR 359 >1F76-A nrPDB Length = 336 Score = 348 bits (892), Expect = 3e-96, Method: Composition-based stats. Identities = 135/347 (38%), Positives = 195/347 (56%), Gaps = 22/347 (6%) Query: 37 YAEYLMPGLQRLLDPESAHRLAVRV------TSLGLLPRATFQDSDMLEVKVLGHKFRNP 90 Y ++ L + LDPE AH + T L R Q V +G F+NP Sbjct: 2 YYPFVRKALFQ-LDPERAHEFTFQQLRRITGTPFEALVR---QKVPAKPVNCMGLTFKNP 57 Query: 91 VGIAAGFDKNGEAVDGLYKLGFGFVEVGSVTPQPQEGNPRPRVFRLPEDQAVINRYGFNS 150 +G+AAG DK+GE +D L +GFG +E+G+VTP+PQ GN +PR+FRL + + +INR GFN+ Sbjct: 58 LGLAAGLDKDGECIDALGAMGFGSIEIGTVTPRPQPGNDKPRLFRLVDAEGLINRMGFNN 117 Query: 151 HGLSVVEHRLRARQQKQAQLTADGLPLGINLGKNKTS--EDAAADYAEGVRTLGPLADYL 208 G+ + ++ LGIN+GKNK + E DY + + A Y+ Sbjct: 118 LGVDNLVENVKKAH--------YDGVLGINIGKNKDTPVEQGKDDYLICMEKIYAYAGYI 169 Query: 209 VVNVSSPNTAGLRSLQGKTELRHLLSKVLQERDALKGTRK--PAVLVKIAPDLTAQDKED 266 +N+SSPNT GLR+LQ L LL+ + +++ L+ + VKIAPDL+ ++ Sbjct: 170 AINISSPNTPGLRTLQYGEALDDLLTAIKNKQNDLQAMHHKYVPIAVKIAPDLSEEELIQ 229 Query: 267 IASVARELGIDGLIVTNTTVSRPVGLQGALRSETGGLSGKPLRDLSTQTIREMYALTQGR 326 +A IDG+I TNTT+ R + +TGGLSG+PL+ ST+ IR + GR Sbjct: 230 VADSLVRHNIDGVIATNTTLDRSLVQGMKNCDQTGGLSGRPLQLKSTEIIRRLSLELNGR 289 Query: 327 IPIIGVGGVSSGQDALEKIQAGASLVQLYTALIFLGPPVVVRVKREL 373 +PIIGVGG+ S A EKI AGASLVQ+Y+ IF GPP++ + + Sbjct: 290 LPIIGVGGIDSVIAAREKIAAGASLVQIYSGFIFKGPPLIKEIVTHI 336 >4WZH-A nrPDB Length = 347 Score = 338 bits (867), Expect = 2e-93, Method: Composition-based stats. Identities = 89/351 (25%), Positives = 145/351 (41%), Gaps = 45/351 (12%) Query: 65 GLLPRATF-----------QDSDMLEVKVLGHKFRNPVGIAAG-FDKNGEAVDGLYKLGF 112 GL+PR + + S L+V +LG+ F NP AAG E + + + Sbjct: 13 GLVPRGSHMASMTGGGQMGRGSMSLQVGILGNTFANPFMNAAGVMCSTEEELAAMTESTS 72 Query: 113 GFVEVGSVTPQPQEGNPRPRVFRLPEDQAVINRYGFNSHGLSVVEHRLRARQQKQAQLTA 172 G + S TP +EGNP PR + LP IN G + G AR ++ Sbjct: 73 GSLITKSCTPALREGNPAPRYYTLP--LGSINSMGLPNKGFDFYLAY-SARHHDYSRK-- 127 Query: 173 DGLPLGINLGKNKTSEDAAADYAEGVRTLGPLAD----YLVVNVSSPNTAGLRSLQGKTE 228 PL I++ E+A E + L P+A L +N+S PN G + + Sbjct: 128 ---PLFISISGFSAEENA-----EMCKRLAPVAAEKGVILELNLSCPNVPGKPQVAYDFD 179 Query: 229 -LRHLLSKVLQERDALKGTRKPAVLVKIAPDLTAQDKEDIASVARELGIDGL-------I 280 +R L+ + + G + P D A+ V I+ + + Sbjct: 180 AMRRYLAAISEAYPHPFGVKMPPYFDFAHFDAAAEILNQFPKVQFITCINSIGNGLVIDV 239 Query: 281 VTNTTVSRPVGLQGALRSETGGLSGKPLRDLSTQTIREMYALTQGRIPIIGVGGVSSGQD 340 T + V +P + GGL G+ + + + Y G++ I G GGV +G+D Sbjct: 240 ETESVVIKP-------KQGFGGLGGRYVFPTALANVNAFYRRCPGKL-IFGCGGVYTGED 291 Query: 341 ALEKIQAGASLVQLYTALIFLGPPVVVRVKRELEALLKERGFTTVTDAIGA 391 A + AGAS+VQ+ TAL G + R+ EL ++ ++G+ + + G Sbjct: 292 AFLHVLAGASMVQVGTALHEEGAAIFERLTAELLDVMAKKGYKALDEFRGK 342 >3W7D-A nrPDB Length = 313 Score = 333 bits (853), Expect = 9e-92, Method: Composition-based stats. Identities = 86/333 (25%), Positives = 134/333 (40%), Gaps = 42/333 (12%) Query: 76 DMLEVKVLGHKFRNPVGIAAG-FDKNGEAVDGLYKLGFGFVEVGSVTPQPQEGNPRPRVF 134 L++ +L H F NP AAG E + + G + S T P++GNP PR Sbjct: 1 MCLKLNLLDHVFANPFMNAAGVLCSTEEDLRCMTASSSGALVSKSCTSAPRDGNPEPRYM 60 Query: 135 RLPEDQAVINRYGFNSHGLSVVEHR---LRARQQKQAQLTADGLPLGINLGKNKTSEDAA 191 P IN G + G L +K L+ GL + N+ Sbjct: 61 AFP--LGSINSMGLPNLGFDFYLKYASDLHDYSKKPLFLSISGLSVEENVAM-------- 110 Query: 192 ADYAEGVRTLGPLAD----YLVVNVSSPNTAGLRSLQGKTE-LRHLLSKVLQERDALKGT 246 VR L P+A L +N+S PN G + E +R L +V G Sbjct: 111 ------VRRLAPVAQEKGVLLELNLSCPNVPGKPQVAYDFEAMRTYLQQVSLAYGLPFGV 164 Query: 247 RKPAVLVKIAPDLTAQDKEDIA-----SVARELGIDGLIV---TNTTVSRPVGLQGALRS 298 + P D A + + +G +GL++ + + V +P + Sbjct: 165 KMPPYFDIAHFDTAAAVLNEFPLVKFVTCVNSVG-NGLVIDAESESVVIKP-------KQ 216 Query: 299 ETGGLSGKPLRDLSTQTIREMYALTQGRIPIIGVGGVSSGQDALEKIQAGASLVQLYTAL 358 GGL GK + + + Y ++ + G GGV SG+DA I AGAS+VQ+ TAL Sbjct: 217 GFGGLGGKYILPTALANVNAFYRRCPDKL-VFGCGGVYSGEDAFLHILAGASMVQVGTAL 275 Query: 359 IFLGPPVVVRVKRELEALLKERGFTTVTDAIGA 391 GP + R++ EL ++ +G+ T+ + G Sbjct: 276 QEEGPGIFTRLEDELLEIMARKGYRTLEEFRGR 308 >3GZ3-A nrPDB Length = 354 Score = 332 bits (851), Expect = 2e-91, Method: Composition-based stats. Identities = 91/352 (25%), Positives = 144/352 (40%), Gaps = 43/352 (12%) Query: 65 GLLPRATF-----------QDSDMLEVKVLGHKFRNPVGIAAG-FDKNGEAVDGLYKLGF 112 GL+P + + S L+V +L + F NP AAG E + + + Sbjct: 13 GLVPAGSHMASMTGGQQMGRGSMSLQVNLLNNTFANPFMNAAGVMCTTTEELVAMTESAS 72 Query: 113 GFVEVGSVTPQPQEGNPRPRVFRLPEDQAVINRYGFNSHGLSVVEHRL---RARQQKQAQ 169 G + S TP +EGNP PR LP IN G ++G +K Sbjct: 73 GSLVSKSCTPALREGNPTPRYQALP--LGSINSMGLPNNGFDFYLAYAAEQHDYGKKPLF 130 Query: 170 LTADGLPLGINLGKNKTSEDAAADYAEGVRTLGPLADYLVVNVSSPNTAGLRSLQGKTE- 228 L+ GL + N+ K AA +GV L +N+S PN G + + Sbjct: 131 LSMSGLSMRENVEMCK--RLAAVATEKGV--------ILELNLSCPNVPGKPQVAYDFDA 180 Query: 229 LRHLLSKVLQERDALKGTRKPAVLVKIAPDLTAQDKEDIASVARELGID----GLIV--- 281 +R L+ V + G + P D A+ + V I+ GL++ Sbjct: 181 MRQCLTAVSEVYPHSFGVKMPPYFDFAHFDAAAEILNEFPKVQFITCINSIGNGLVIDAE 240 Query: 282 TNTTVSRPVGLQGALRSETGGLSGKPLRDLSTQTIREMYALTQGRIPIIGVGGVSSGQDA 341 T + V +P + GGL G+ + + I Y G++ I G GGV +G+DA Sbjct: 241 TESVVIKP-------KQGFGGLGGRYVLPTALANINAFYRRCPGKL-IFGCGGVYTGEDA 292 Query: 342 LEKIQAGASLVQLYTALIFLGPPVVVRVKRELEALLKERGFTTVTDAIGADH 393 + AGAS+VQ+ TAL GP + R+ EL ++ ++ + T+ + G Sbjct: 293 FLHVLAGASMVQVGTALQEEGPSIFERLTSELLGVMAKKRYQTLDEFRGKVR 344 >5XFW-A nrPDB Length = 334 Score = 331 bits (848), Expect = 3e-91, Method: Composition-based stats. Identities = 85/330 (25%), Positives = 135/330 (40%), Gaps = 32/330 (9%) Query: 74 DSDMLEVKVLGHKFRNPVGIAAG-FDKNGEAVDGLYKLGFGFVEVGSVTPQPQEGNPRPR 132 S L+V +LGH+F NP AAG E + + + G + S T P+ GNP PR Sbjct: 20 GSMSLKVNILGHEFSNPFMNAAGVLCTTEEDLRRMTESESGSLIGKSCTLAPRTGNPEPR 79 Query: 133 VFRLPEDQAVINRYGFNSHGLSVVEHRL---RARQQKQAQLTADGLPLGINLGKNKTSED 189 F LP IN G + G+ +K L+ GL + ++ K Sbjct: 80 YFGLP--LGSINSMGLPNLGVDFYLSYAAQTHDYSRKPLFLSMSGLSVEESVEMVKKLVP 137 Query: 190 AAADYAEGVRTLGPLADYLVVNVSSPNTAGLRSLQGKTEL-RHLLSKVLQERDALKGTRK 248 + L +N+S PN G + + R L KV + G + Sbjct: 138 ITKE----------KGTILELNLSCPNVPGKPQVGYDFDTTRTYLQKVSEAYGLPFGVKM 187 Query: 249 PAVLVKIAPDLTAQDKEDIASVARELGID----GLIV---TNTTVSRPVGLQGALRSETG 301 P D+ A D V ++ GL++ T V +P + G Sbjct: 188 PPYFDIAHFDMAAAVLNDFPLVKFITCVNSIGNGLVIDPANETVVIKP-------KQGFG 240 Query: 302 GLSGKPLRDLSTQTIREMYALTQGRIPIIGVGGVSSGQDALEKIQAGASLVQLYTALIFL 361 GL GK + + + + ++ + G GGV SG++A I AGAS+VQ+ TAL Sbjct: 241 GLGGKYVLPTALANVNAFFRRCPDKL-VFGCGGVYSGEEAFLHILAGASMVQVGTALHDE 299 Query: 362 GPPVVVRVKRELEALLKERGFTTVTDAIGA 391 GP + R+ +EL+ ++ +G+ T+ + G Sbjct: 300 GPIIFARLNKELQEIMTNKGYKTLDEFRGR 329 >4XQ6-A nrPDB Length = 344 Score = 327 bits (839), Expect = 4e-90, Method: Composition-based stats. Identities = 145/347 (41%), Positives = 199/347 (57%), Gaps = 32/347 (9%) Query: 65 GLLPRATFQ--------------DSDMLEVKVLGHKFRNPVGIAAGFDKNGEAVDGLYKL 110 GL+PR + +L V G +F P+G+AAGFDK+G A+ + Sbjct: 13 GLVPRGSHMVAPVRRLLRRLLGPTDPVLASTVFGVRFPAPLGLAAGFDKDGTALSSWGAM 72 Query: 111 GFGFVEVGSVTPQPQEGNPRPRVFRLPEDQAVINRYGFNSHGLSVVEHRLRARQQKQAQL 170 GFG+ E+G+VT PQ GNP PR+FRL +D+A++NR GFN+HG + RL AR + + Sbjct: 73 GFGYAEIGTVTAHPQPGNPAPRLFRLADDRALLNRMGFNNHGARALAIRL-ARHRPE--- 128 Query: 171 TADGLPLGINLGKNKTSE--DAAADYAEGVRTLGPLADYLVVNVSSPNTAGLRSLQGKTE 228 +P+G+N+GK K + DA DY R +GPLA YLVVNVSSPNT GLR LQ Sbjct: 129 ----IPIGVNIGKTKKTPAGDAVNDYRASARMVGPLASYLVVNVSSPNTPGLRDLQAVES 184 Query: 229 LRHLLSKVLQERDALKGTRKPAVLVKIAPDLTAQDKEDIASVARELGIDGLIVTNTTVSR 288 LR +LS V E VLVKIAPDL+ D +DIA +A EL + G++ TNTTVSR Sbjct: 185 LRPILSAVRAETST-------PVLVKIAPDLSDSDLDDIADLAVELDLAGIVATNTTVSR 237 Query: 289 P-VGLQGALRSETGGLSGKPLRDLSTQTIREMYALTQGRIPIIGVGGVSSGQDALEKIQA 347 + G R GG+SG PL + Q +R +Y R+ +I VGG+ + DA E+I A Sbjct: 238 DGLTTPGVDRLGPGGISGPPLAQRAVQVLRRLYDRVGDRLALISVGGIETADDAWERITA 297 Query: 348 GASLVQLYTALIFLGPPVVVRVKRELEALLKERGFTTVTDAIGADHR 394 GASL+Q YT I+ G + + L + GF ++ +A+G+ R Sbjct: 298 GASLLQGYTGFIYGGERWAKDIHEGIARRLHDGGFGSLHEAVGSARR 344 >1JUE-A nrPDB Length = 311 Score = 313 bits (803), Expect = 6e-86, Method: Composition-based stats. Identities = 79/329 (24%), Positives = 133/329 (40%), Gaps = 36/329 (10%) Query: 77 MLEVKVLGHKFRNPVGIAAGF-DKNGEAVDGLYKLGFGFVEVGSVTPQPQEGNPRPRVFR 135 ML KF NP A+G E ++ L G S T + +EGNP PR Sbjct: 1 MLNTTFANAKFANPFMNASGVHCMTIEDLEELKASQAGAYITKSSTLEKREGNPLPRYVD 60 Query: 136 LPEDQAVINRYGFNSHGLSVVEHRLRARQQKQA-----QLTADGLPLGINLGKNKTSEDA 190 L + IN G + G + Q++ A + G+ N+ K +++ Sbjct: 61 L--ELGSINSMGLPNLGFDYYLDYVLKNQKENAQEGPIFFSIAGMSAAENIAMLKKIQES 118 Query: 191 AADYAEGVRTLGPLADYLVVNVSSPNTAGLRSLQGKTE-LRHLLSKVLQERDALKGTRKP 249 + +N+S PN G L E LL +V G + P Sbjct: 119 ------------DFSGITELNLSCPNVPGKPQLAYDFEATEKLLKEVFTFFTKPLGVKLP 166 Query: 250 AVLVKIAPDLTAQDKEDIA----SVARELGIDGLIV---TNTTVSRPVGLQGALRSETGG 302 + D+ A+ + +G +GL + + V +P + GG Sbjct: 167 PYFDLVHFDIMAEILNQFPLTYVNSVNSIG-NGLFIDPEAESVVIKP-------KDGFGG 218 Query: 303 LSGKPLRDLSTQTIREMYALTQGRIPIIGVGGVSSGQDALEKIQAGASLVQLYTALIFLG 362 + G ++ + +R Y + I IIG GG+ +GQDA E + GA+++Q+ TAL G Sbjct: 219 IGGAYIKPTALANVRAFYTRLKPEIQIIGTGGIETGQDAFEHLLCGATMLQIGTALHKEG 278 Query: 363 PPVVVRVKRELEALLKERGFTTVTDAIGA 391 P + R+ +ELE ++ ++G+ ++ D G Sbjct: 279 PAIFDRIIKELEEIMNQKGYQSIADFHGK 307 >5UE9-A nrPDB Length = 306 Score = 290 bits (741), Expect = 9e-79, Method: Composition-based stats. Identities = 93/321 (28%), Positives = 146/321 (45%), Gaps = 29/321 (9%) Query: 76 DMLEVKVLGHKFRNPVGIAAGFDKNGEAVDGLYKLG-FGFVEVGSVTPQPQEGNPRPRVF 134 + L VK+ G +NP+ A+G GE Y L G + V + T P+ GNP PRV Sbjct: 1 NRLSVKLPGLDLKNPIIPASGCFGFGEEYAKYYDLNKLGSIMVKATTLHPRFGNPTPRVA 60 Query: 135 RLPEDQAVINRYGFNSHGLSVVEHRLRARQQKQAQLTADGLPLGINLGKNKTSEDAAADY 194 ++N G + GL V+ A + LP+ N+ ++ DY Sbjct: 61 E--TASGMLNAIGLQNPGLEVI----MAEKLPWLNENFPDLPIIANVAGSEE-----DDY 109 Query: 195 AEGVRTLG--PLADYLVVNVSSPNTA-GLRSLQGKTELRHLLSKVLQERDALKGTRKPAV 251 +G P + +N+S PN G ++ ++ L K A K K + Sbjct: 110 VAVCAKIGDAPNVKVIELNISCPNVKHGGQAFGTDPDVAAALVK------ACKAVSKVPL 163 Query: 252 LVKIAPDLTAQDKEDIASVARELGIDGLIVTNTTVSRPVGLQ---GALRSETGGLSGKPL 308 VK++P++T D IA G DGL + NT + L+ L + TGGLSG + Sbjct: 164 YVKLSPNVT--DIVPIAKAVEAAGADGLTMINTLMGVRFDLKTRKPVLANITGGLSGPAI 221 Query: 309 RDLSTQTIREMYALTQGRIPIIGVGGVSSGQDALEKIQAGASLVQLYTALIFLGPPVVVR 368 + ++ + I ++ + IPIIG+GGV S QD LE AGAS V + TA F P V + Sbjct: 222 KPVALKLIHQVAQVVD--IPIIGMGGVESAQDVLEMYMAGASAVAVGTAN-FADPFVCPK 278 Query: 369 VKRELEALLKERGFTTVTDAI 389 + +L ++ + G ++ + I Sbjct: 279 IIEKLPEVMDQYGIDSLENLI 299 >3OIX-A nrPDB Length = 345 Score = 289 bits (740), Expect = 1e-78, Method: Composition-based stats. Identities = 78/345 (22%), Positives = 131/345 (37%), Gaps = 35/345 (10%) Query: 65 GLLPRATFQDSD------------MLEVKVLGHKFRNPVGIAAG-FDKNGEAVDGLYKLG 111 GL+PR + S + F N + AAG + E + + Sbjct: 13 GLVPRGSHMASMTGGQQMGRGSMVSTHTTIGSFDFDNCLMNAAGVYCMTREELAAIDHSE 72 Query: 112 FGFVEVGSVTPQPQEGNPRPRVFRLPEDQAVINRYGFNSHGLSVVEHRLRARQQKQAQLT 171 G + T + + GNP+PR IN G + G++ + Q++ Sbjct: 73 AGSFVTKTGTLEERAGNPQPRYAD--TKLGSINSMGLPNLGINYYLDYVTELQKQPDSKN 130 Query: 172 ADGLPLGINLGKNKTSEDAAADYAEGVRTLGPLADYLVVNVSSPNTAGLRSLQGKTEL-R 230 +G++ + T + +N+S PN G + E Sbjct: 131 HFLSLVGMSPEETHTILKMVEASK--------YQGLVELNLSCPNVPGKPQIAYDFETTD 182 Query: 231 HLLSKVLQERDALKGTRKPAVLVKIAPDLTAQDKE----DIASVARELGIDGLIVTNTTV 286 +LS+V G + P + D A + +G +I T V Sbjct: 183 QILSEVFTYFTKPLGIKLPPYFDIVHFDQAAAIFNKYPLTFVNCINSIGNGLVIEDETVV 242 Query: 287 SRPVGLQGALRSETGGLSGKPLRDLSTQTIREMYALTQGRIPIIGVGGVSSGQDALEKIQ 346 +P ++ GG+ G ++ + + Y I IIG GGV +G+DA E I Sbjct: 243 IKP-------KNGFGGIGGDYVKPTALANVHAFYKRLNPSIQIIGTGGVKTGRDAFEHIL 295 Query: 347 AGASLVQLYTALIFLGPPVVVRVKRELEALLKERGFTTVTDAIGA 391 GAS+VQ+ TAL GP + R+ +EL+A++ E+G+ T+ D G Sbjct: 296 CGASMVQIGTALHQEGPQIFKRITKELKAIMTEKGYETLEDFRGK 340 >1EP3-A nrPDB Length = 311 Score = 285 bits (728), Expect = 3e-77, Method: Composition-based stats. Identities = 94/325 (28%), Positives = 147/325 (45%), Gaps = 29/325 (8%) Query: 72 FQDSDMLEVKVLGHKFRNPVGIAAGFDKNGEAVDGLYKLG-FGFVEVGSVTPQPQEGNPR 130 +++ L VK+ G +NP+ A+G GE Y L G + V + T P+ GNP Sbjct: 1 MTENNRLSVKLPGLDLKNPIIPASGCFGFGEEYAKYYDLNKLGSIMVKATTLHPRFGNPT 60 Query: 131 PRVFRLPEDQAVINRYGFNSHGLSVVEHRLRARQQKQAQLTADGLPLGINLGKNKTSEDA 190 PRV ++N G + GL V+ + LP+ N+ ++ Sbjct: 61 PRVAE--TASGMLNAIGLQNPGLEVI----MTEKLPWLNENFPELPIIANVAGSEE---- 110 Query: 191 AADYAEGVRTLGPLADY--LVVNVSSPNTA-GLRSLQGKTELRHLLSKVLQERDALKGTR 247 ADY +G A+ + +N+S PN G ++ E+ L K A K Sbjct: 111 -ADYVAVCAKIGDAANVKAIELNISCPNVKHGGQAFGTDPEVAAALVK------ACKAVS 163 Query: 248 KPAVLVKIAPDLTAQDKEDIASVARELGIDGLIVTNTTVSRPVGL---QGALRSETGGLS 304 K + VK++P++T D IA G DGL + NT + L Q L + TGGLS Sbjct: 164 KVPLYVKLSPNVT--DIVPIAKAVEAAGADGLTMINTLMGVRFDLKTRQPILANITGGLS 221 Query: 305 GKPLRDLSTQTIREMYALTQGRIPIIGVGGVSSGQDALEKIQAGASLVQLYTALIFLGPP 364 G ++ ++ + I ++ IPIIG+GGV++ QD LE AGAS V + TA F P Sbjct: 222 GPAIKPVALKLIHQVAQ--DVDIPIIGMGGVANAQDVLEMYMAGASAVAVGTAN-FADPF 278 Query: 365 VVVRVKRELEALLKERGFTTVTDAI 389 V ++ +L L+ + ++ I Sbjct: 279 VCPKIIDKLPELMDQYRIESLESLI 303 >2J6X-A nrPDB Length = 374 Score = 43.2 bits (100), Expect = 2e-04, Method: Composition-based stats. Identities = 64/340 (18%), Positives = 111/340 (32%), Gaps = 66/340 (19%) Query: 74 DSDMLEVKVLGHKFRNPVGIAA----GF-DKNGEAVDGLYKLGFGFVEV-----GSVTPQ 123 ++ ++LGHK + P +A G EA FG + G+ + Sbjct: 72 EAPDTSTEILGHKIKAPFIMAPIAAHGLAHTTKEAGTARAVSEFGTIMSISAYSGATFEE 131 Query: 124 PQEG-NPRPRVFRLPEDQAVINRYGFNSHGLSVVEHRLRARQQKQAQLTADGLPLGINLG 182 EG N PR F++ + ++R + K TA L + Sbjct: 132 ISEGLNGGPRWFQIYMAK-------------DDQQNRDILDEAKSDGATAIILTADSTVS 178 Query: 183 KNKT-SEDAAADYAEGVRTLGPLADYLVVNVSSPNTAGLRSLQGKTELRHLLSKVLQERD 241 N+ Y G+ + +S N + + + ++E Sbjct: 179 GNRDRDVKNKFVYPFGMPIVQRYLRGTAEGMSLNNI-------YGASKQKISPRDIEEIA 231 Query: 242 ALKGTRKPAVLVKIAPDLTAQDKEDIASVARELGIDGLIVTNTTVSRPVGLQGALRSETG 301 A G V VK Q ED A +A + G G+ V+N Sbjct: 232 AHSGL---PVFVK-----GIQHPED-ADMAIKAGASGIWVSNH----------------- 265 Query: 302 GLSGKPLRDLSTQTIREMYALTQGRIPIIGVGGVSSGQDALEKIQAGASLVQLYTALIF- 360 G S T+ + R+PI+ GV G+ + + +GA +V L ++F Sbjct: 266 GARQLYEAPGSFDTLPAIAERVNKRVPIVFDSGVRRGEHVAKALASGADVVALGRPVLFG 325 Query: 361 -------LGPPVVVRVKRELEALLKERGFTTVTDAIGADH 393 V+ +++L +++ G V D G D Sbjct: 326 LALGGWQGAYSVLDYFQKDLTRVMQLTGSQNVEDLKGLDL 365 >5LSM-A nrPDB Length = 359 Score = 43.2 bits (100), Expect = 2e-04, Method: Composition-based stats. Identities = 42/201 (20%), Positives = 68/201 (33%), Gaps = 32/201 (15%) Query: 171 TADGLPLGINLGKNKTSEDAAADYAEGVRTLGPLADYLVVNVSSPNT--AGLRSLQGKTE 228 + P+ +N ++ AA A + L P + N+ PN AG + Sbjct: 60 SQTAKPINVNFFCHREPVAQAAKQAAWLEQLAPY--FAEFNLD-PNAQPAGAQRTPYSKA 116 Query: 229 LRHLLSKVLQERDALKGTRKPAVLVKIAPDLTAQDKEDIASVARELGIDGLIVTNTTVSR 288 +L+K +V L ++ + + +I T TTV Sbjct: 117 QAEVLAKFK------------PEVVSFHFGLPDEELL----LEIKSWGSKVISTATTVEE 160 Query: 289 PVGLQGALRS-------ETGGLSGKPLRDLSTQTIREMYALTQ----GRIPIIGVGGVSS 337 + L+ E GG G L + T+ + L Q IP+I GG+ Sbjct: 161 ALWLEARGADAIIAQGLEAGGHRGHFLSEDLTEQLGTFSLLPQIIAAVEIPVIAAGGIVD 220 Query: 338 GQDALEKIQAGASLVQLYTAL 358 + GAS VQ+ TA Sbjct: 221 ATTVRAAMTMGASAVQVGTAY 241 >2Z6J-A nrPDB Length = 332 Score = 42.0 bits (97), Expect = 5e-04, Method: Composition-based stats. Identities = 27/153 (17%), Positives = 54/153 (35%), Gaps = 18/153 (11%) Query: 223 LQGKTELRHLLSKVLQERDALKGTRKPAV--LVKIAPDLTAQDKEDIASV--------AR 272 K ++ + K+ D G + V+ DL ++ + + Sbjct: 45 NAPKEVVKANIDKIKSLTDKPFGVNIMLLSPFVEDIVDLVIEEGVKVVTTGAGNPSKYME 104 Query: 273 ELGIDGLIVTNTT----VSRPVGLQGALRSETGGL--SGKPLRDLSTQTIREMYALTQGR 326 G+IV +++ + GA G+ G + + +R++ Sbjct: 105 RFHEAGIIVIPVVPSVALAKRMEKIGADAVIAEGMEAGGHIGKLTTMTLVRQVATAI--S 162 Query: 327 IPIIGVGGVSSGQDALEKIQAGASLVQLYTALI 359 IP+I GG++ G+ A GA VQ+ T + Sbjct: 163 IPVIAAGGIADGEGAAAGFMLGAEAVQVGTRFV 195 >5ZBN-A nrPDB Length = 371 Score = 39.7 bits (91), Expect = 0.002, Method: Composition-based stats. Identities = 27/123 (21%), Positives = 49/123 (39%), Gaps = 10/123 (8%) Query: 279 LIVTNTTVSRPVGLQGALRSETGGLSGKPLRDLSTQTIREMYALTQGRIPIIGVGGVSSG 338 L + ++ G G + S G + + + E+ QGRIP+ GGV G Sbjct: 234 LTAEDARLAVQAGAAGIIVSNHGARQLDYV-PSTIMALEEVVKAAQGRIPVFLDGGVRRG 292 Query: 339 QDALEKIQAGASLVQLYTALIF----LGPPVVVRVK----RELEALLKERGFTTVTDAIG 390 D + + GAS + + ++F G + +V E E + G ++ + I Sbjct: 293 TDVFKALALGASGIFIGRPVVFSLAAEGEAGIKKVLQMLRDEFELTMALSGCRSLNE-IT 351 Query: 391 ADH 393 +H Sbjct: 352 RNH 354 >1MZH-A nrPDB Length = 225 Score = 39.3 bits (90), Expect = 0.003, Method: Composition-based stats. Identities = 40/199 (20%), Positives = 73/199 (36%), Gaps = 38/199 (19%) Query: 174 GLPLGINLGKNKTSEDAAADYAEGVRTLGPLADYLVVNVSSPNTAGLRSLQGKTELRHLL 233 G PLG+N K E A +G + L +V N+S+ +S + + L Sbjct: 61 GFPLGLNKTSVKVKE-AVEAVRDGAQELD-----IVWNLSA-----FKSEKYDFVVEE-L 108 Query: 234 SKVLQERDALKGTRKPAVLVKIAPDLTAQDKEDIASVARELGIDGLIVTNTTVSRPVGLQ 293 ++ +E K V P L ++ + + E G D I T+T Sbjct: 109 KEIFRE--TPSAVHKVIVE---TPYLNEEEIKKAVEICIEAGAD-FIKTST--------- 153 Query: 294 GALRSETGGLSGKPLRDLSTQTIREMYALTQGRIPIIGVGGVSSGQDALEKIQAGASLVQ 353 G R + + +R + + +GRI + GG+ + A+ I+AGA + Sbjct: 154 -----------GFAPRGTTLEEVRLIKSSAKGRIKVKASGGIRDLETAISMIEAGADRIG 202 Query: 354 LYTALIFLGPPVVVRVKRE 372 + + + + E Sbjct: 203 TSSGISIAEEFLKRHLILE 221 >1AL8-A nrPDB Length = 359 Score = 39.3 bits (90), Expect = 0.003, Method: Composition-based stats. Identities = 31/134 (23%), Positives = 51/134 (38%), Gaps = 26/134 (19%) Query: 268 ASVARELGIDGLIVTNTTVSRPVGLQGALRSETGGLSGKPLRDLSTQTIREMYALTQGRI 327 A +A + G G+IV+N G + + + E+ QGRI Sbjct: 238 ARLAVQHGAAGIIVSN----------------HGARQLDYV-PATIMALEEVVKAAQGRI 280 Query: 328 PIIGVGGVSSGQDALEKIQAGASLVQLYTALIF----LGPPVVVRVK----RELEALLKE 379 P+ GGV G D + + GA+ V + ++F G V +V E E + Sbjct: 281 PVFLDGGVRRGTDVFKALALGAAGVFIGRPVVFSLAAEGEAGVKKVLQMMRDEFELTMAL 340 Query: 380 RGFTTVTDAIGADH 393 G ++ + I H Sbjct: 341 SGCRSLKE-ISRSH 353 >4Q4K-A nrPDB Length = 357 Score = 39.0 bits (89), Expect = 0.004, Method: Composition-based stats. Identities = 14/48 (29%), Positives = 26/48 (54%), Gaps = 2/48 (4%) Query: 312 STQTIREMYALTQGRIPIIGVGGVSSGQDALEKIQAGASLVQLYTALI 359 + +R + A G +P++ GG+ G+ ++ GAS VQ+ TA + Sbjct: 198 TLALVRLLAAR--GSLPVVAAGGIMDGRGIRAALELGASAVQMGTAFV 243 >3UOG-A nrPDB Length = 363 Score = 38.2 bits (87), Expect = 0.006, Method: Composition-based stats. Identities = 22/110 (20%), Positives = 41/110 (37%), Gaps = 9/110 (8%) Query: 17 LGGGGLLFTSYLTATGDDH---FYAEYLMPGLQRLLDPESAHRLAVRVTSLGLLPRATFQ 73 LG L F S ++ + A + + +R + H + VR ++ L ++ Sbjct: 13 LGTENLYFQSMMSKWMQEWSTETVAPHDLKLAERPVPEAGEHDIIVRTLAVSL----NYR 68 Query: 74 DSDMLEVKVLGHKFRNPVGIAAGFDKNGEAV-DGLYKLGFGFVEVGSVTP 122 D +LE +G P A+ EAV + + G + + P Sbjct: 69 DKLVLETG-MGLDLAFPFVPASDMSGVVEAVGKSVTRFRPGDRVISTFAP 117 >2ZRW-A nrPDB Length = 368 Score = 36.6 bits (83), Expect = 0.019, Method: Composition-based stats. Identities = 37/257 (14%), Positives = 81/257 (31%), Gaps = 51/257 (19%) Query: 172 ADGLPLGINLGKNKTSEDAAADYAEGVRTLGPLADYLVVNVSSPNTAGLRSLQGKTELRH 231 G+P+G+ + + A + VR + P + N+ G+ L L+ Sbjct: 87 KFGIPMGVGSQRVAIEKAEARESFAIVRKVAPTIPIIA-NL------GMPQLVKGYGLKE 139 Query: 232 LLSKVLQERDALKGTRKPAVLVKIAPDLTAQD----KEDIASVARELGI--------DGL 279 + P+ + E + +++EL + +G+ Sbjct: 140 FQDAIQMIEADAIAVHLNPAQEVFQPEGEPEYQIYALEKLRDISKELSVPIIVKESGNGI 199 Query: 280 IVTNTTVSRPVGLQGALRSETGGLSGKPLR-----------------------DLSTQTI 316 + + G++ S GG + + + + Sbjct: 200 SMETAKLLYSYGIKNFDTSGQGGTNWIAIEMIRDIRRGNWKAESAKNFLDWGVPTAASIM 259 Query: 317 REMYALTQGRIPIIGVGGVSSGQDALEKIQAGASL----VQLYTALIFLGPPV---VVRV 369 Y++ ++G GG+ SG DA + I GA + + + + I + ++ Sbjct: 260 EVRYSV--PDSFLVGSGGIRSGLDAAKAIALGADIAGMALPVLKSAIEGKESLEQFFRKI 317 Query: 370 KRELEALLKERGFTTVT 386 EL+A + G V Sbjct: 318 IFELKAAMMLTGSKDVD 334 >4MM1-A nrPDB Length = 250 Score = 35.5 bits (80), Expect = 0.036, Method: Composition-based stats. Identities = 17/60 (28%), Positives = 29/60 (48%), Gaps = 3/60 (5%) Query: 318 EMYALTQGRIPIIGVGGVSSGQDALEKIQAGASLVQLYTALIFLGPPVVVRVKRELEALL 377 + +I I+G GG+ SG+DA AGA +V T ++ V ++ RE+ + Sbjct: 189 ALVKRCTDQILIVG-GGIRSGEDAARVAGAGADVVVTGT-VVENSDNVEDKI-REIVEGM 245 >3SGZ-A nrPDB Length = 352 Score = 35.5 bits (80), Expect = 0.037, Method: Composition-based stats. Identities = 34/167 (20%), Positives = 60/167 (35%), Gaps = 12/167 (7%) Query: 229 LRHLLSKVLQERDALKGTRKPAVLVKIAPDLTAQDKEDIASVARELGIDGLIVTNTTVSR 288 L+ L + +E+ P + K + + + L + ++ Sbjct: 179 LKAALRALKEEKPTQ---SVPVLFPKASFCWNDLSLLQSITRLPIILKGILTKEDAELAM 235 Query: 289 PVGLQGALRSETGGLSGKPLRDLSTQTIREMYALTQGRIPIIGVGGVSSGQDALEKIQAG 348 +QG + S GG + S +RE+ A +G+I + GGV +G D L+ + G Sbjct: 236 KHNVQGIVVSNHGGRQLDEVS-ASIDALREVVAAVKGKIEVYMDGGVRTGTDVLKALALG 294 Query: 349 ASLVQLYT----ALIFLGPPVVVRVKR----ELEALLKERGFTTVTD 387 A + L L G V V EL + G +V + Sbjct: 295 ARCIFLGRPILWGLACKGEDGVKEVLDILTAELHRCMTLSGCQSVAE 341 >6HUL-A nrPDB Length = 241 Score = 35.5 bits (80), Expect = 0.045, Method: Composition-based stats. Identities = 33/158 (20%), Positives = 64/158 (40%), Gaps = 15/158 (9%) Query: 236 VLQERDALKGTRKPAVLVKIAPDLTAQ---DKEDIASVARELGIDGLIVTNTTVSRPVGL 292 V Q + L + + + PDL D + I + + G+ +I T+ +V + Sbjct: 86 VDQLENFLNMIKDVKLDGILFPDLLIDYIDDLDKIDGIIKNKGLKNVIFTSPSVPDLLIH 145 Query: 293 QGALRS------ETGGLSGKPLRDLSTQTIREMYALTQGRIPIIGVGGVSSGQDALEKIQ 346 + + S +G P+ Q I + L + ++ I+G G +SS D + + Sbjct: 146 KVSKISDLFLYYGVRPTTGVPIPVSVKQLINRVRNLVENKL-IVGFG-LSSESDLRDALS 203 Query: 347 AGASLVQLYTALIFL----GPPVVVRVKRELEALLKER 380 AGA + + T I G + + ++ A+L E Sbjct: 204 AGADGIAIGTVFIEEIERNGVKSAINLVKKFRAILDEY 241 >3T8S-A nrPDB Length = 585 Score = 34.7 bits (78), Expect = 0.062, Method: Composition-based stats. Identities = 22/95 (23%), Positives = 34/95 (35%), Gaps = 10/95 (10%) Query: 249 PAVLVKIAPDLTAQDKEDIASVARELGIDGLIVTNTTVSRPVGLQGALRSETGGLSGKPL 308 V++KI +DKE A ++ + R + G ++GK Sbjct: 395 KPVMLKIGTSPLKEDKEAFA----------IVPVSPAEVRDLDFANDASKVLGSIAGKLE 444 Query: 309 RDLSTQTIREMYALTQGRIPIIGVGGVSSGQDALE 343 + TQ R + GG +SGQD LE Sbjct: 445 KGTITQNERRSVTKLLEDLVYFVTGGTNSGQDVLE 479 >1N4K-A nrPDB Length = 381 Score = 34.7 bits (78), Expect = 0.062, Method: Composition-based stats. Identities = 22/95 (23%), Positives = 34/95 (35%), Gaps = 10/95 (10%) Query: 249 PAVLVKIAPDLTAQDKEDIASVARELGIDGLIVTNTTVSRPVGLQGALRSETGGLSGKPL 308 V++KI +DKE A ++ + R + G ++GK Sbjct: 189 KPVMLKIGTSPLKEDKEAFA----------IVPVSPAEVRDLDFANDASKVLGSIAGKLE 238 Query: 309 RDLSTQTIREMYALTQGRIPIIGVGGVSSGQDALE 343 + TQ R + GG +SGQD LE Sbjct: 239 KGTITQNERRSVTKLLEDLVYFVTGGTNSGQDVLE 273 >1YPF-A nrPDB Length = 336 Score = 34.7 bits (78), Expect = 0.064, Method: Composition-based stats. Identities = 13/63 (20%), Positives = 29/63 (46%), Gaps = 6/63 (9%) Query: 328 PIIGVGGVSSGQDALEKIQAGASLVQLYTAL--IFLGPPVVVRVKRELEALLKERGFTTV 385 PII GG+ + D + I+ GA++V + + P ++++ L + F + Sbjct: 212 PIIADGGIRTNGDVAKSIRFGATMVMIGSLFAGHEESPG--ETIEKD--GKLYKEYFGSA 267 Query: 386 TDA 388 ++ Sbjct: 268 SEF 270 >4XBS-A nrPDB Length = 265 Score = 34.7 bits (78), Expect = 0.068, Method: Composition-based stats. Identities = 22/96 (22%), Positives = 40/96 (41%), Gaps = 7/96 (7%) Query: 262 QDKEDIASVARELG-IDGLIVTNTTVSRPVGLQGALRSETGGL------SGKPLRDLSTQ 314 D + +A G I +I+ N +++ ++ SE G +G + Sbjct: 148 ADIQGLADAVHAKGKILKVILENALLTKDEIVRACQLSEKAGADFVKTSTGFSTSGAKVE 207 Query: 315 TIREMYALTQGRIPIIGVGGVSSGQDALEKIQAGAS 350 ++ M R+ + GG+ S ++AL I AGAS Sbjct: 208 DVKLMRETVGDRLGVKASGGIHSREEALAMIDAGAS 243 >2CDH-0 nrPDB Length = 226 Score = 34.3 bits (77), Expect = 0.086, Method: Composition-based stats. Identities = 34/152 (22%), Positives = 60/152 (39%), Gaps = 27/152 (17%) Query: 224 QGKTELRHLLSKVLQERDALKGTRKPAVLVKIAPDLTAQDKEDIASVARELGIDGLIVTN 283 + + + V ++ L+ +LVK +TA+D A +A + G G+IV+N Sbjct: 84 AERAGFKAIALTVWKDVAWLQTITSLPILVKGV--ITAED----ARLAVQHGAAGIIVSN 137 Query: 284 TTVSRPVGLQGALRSETGGLSGKPLRDLSTQTIREMYALTQGRIPIIGVGGVSSGQDALE 343 G + + + E+ QGRIP+ GGV G D + Sbjct: 138 ----------------HGARQLDYV-PATIMALEEVVKAAQGRIPVFLDGGVRRGTDVFK 180 Query: 344 KIQAGASLVQLYTALIF----LGPPVVVRVKR 371 + GA+ V + ++F G V +V + Sbjct: 181 ALALGAAGVFIGRPVVFSLAAEGEAGVKKVLQ 212 >4JEJ-A nrPDB Length = 244 Score = 33.6 bits (75), Expect = 0.15, Method: Composition-based stats. Identities = 37/217 (17%), Positives = 61/217 (28%), Gaps = 29/217 (13%) Query: 158 HRLRARQQKQAQLTADGLPLG-INLGKNKTSEDAAADYAEGVRTLGPLADYLVVNVSSPN 216 ++ L + P I +G + D ++ L + Sbjct: 31 DKIVWENLDHLLLKINQSPATHIFVGGSIVESTIIEDLIAQLKQKTRLPVVI-------- 82 Query: 217 TAGLRSLQGKTELRHLLSKVLQERDALKGTRKPAVLVKIAPDLTAQDKEDIAS------V 270 G S Q + +L L V+ AP L + E I++ Sbjct: 83 FPGDPS-QISPKADAILFLSLLSGRNPD--YLIEYQVQAAPILKKTNLEVISTGYILIES 139 Query: 271 ARELGIDGLIVTNTTVSRPVGLQGALRSETGGLSGKPL---------RDLSTQTIREMYA 321 E + + T L A L K + + + + I + Sbjct: 140 GNETAVARVSKTEPLNRENFDLALATAQAGEMLGSKLIYLEAGSGAKKPVPLEMISVISQ 199 Query: 322 LTQGRIPIIGVGGVSSGQDALEKIQAGASLVQLYTAL 358 IPII GG+ + AGA LV + TA Sbjct: 200 --NVEIPIIVGGGIVDLHGIKKAYNAGADLVVIGTAF 234 >2RDU-A nrPDB Length = 387 Score = 33.6 bits (75), Expect = 0.15, Method: Composition-based stats. Identities = 17/70 (24%), Positives = 28/70 (40%), Gaps = 4/70 (5%) Query: 310 DLSTQTIREMYALTQGRIPIIGVGGVSSGQDALEKIQAGASLVQLYT----ALIFLGPPV 365 + + E+ +G++ + GGV G D L+ + GA V + L F G Sbjct: 286 PATIDVLPEIVEAVEGKVEVFLDGGVRKGTDVLKALALGAKAVFVGRPIVWGLAFQGEKG 345 Query: 366 VVRVKRELEA 375 V V L+ Sbjct: 346 VQDVLEILKE 355 >6C9R-A nrPDB Length = 337 Score = 33.2 bits (74), Expect = 0.19, Method: Composition-based stats. Identities = 21/85 (24%), Positives = 34/85 (40%), Gaps = 6/85 (7%) Query: 18 GGGGLLFTSYLTATGDDHFYAEYLMPGLQRL---LDPESAHRLAVRVTSLGLLP-RATFQ 73 G L F S++T ++LM R L PE H++++ L+ R Sbjct: 4 GTENLYFQSHMTIAVTGSIATDHLMRFPGRFSEQLLPEHLHKVSLSFLVDDLVMHRGGVA 63 Query: 74 DSDMLEVKVLGHKFRNPVGIAAGFD 98 + + VLG + + AAG D Sbjct: 64 GNMAFAIGVLGGEVA--LVGAAGAD 86 >1SZG-A nrPDB Length = 511 Score = 32.8 bits (73), Expect = 0.26, Method: Composition-based stats. Identities = 43/227 (18%), Positives = 82/227 (36%), Gaps = 34/227 (14%) Query: 186 TSEDAAADYAEGVRTLGPLADYLVVNVSSPNTAGLRSLQGKTELRHLLSKVLQERDALKG 245 + D + V LG A ++ V+ L + +L K + K Sbjct: 257 SDRKITDDLVKNVEKLGVKALFVTVD-----APSLGQREKDMKL-----KFSNTKAGPKA 306 Query: 246 TRKP----------AVLVKIAPDLTAQDKEDIAS-VARELGIDGLIVTNTTV-SRPVGLQ 293 +K A+ I P LT +D E++ + I G+ T + + +G+ Sbjct: 307 MKKTNVEESQGASRALSKFIDPSLTWKDIEELKKKTKLPIVIKGVQRTEDVIKAAEIGVS 366 Query: 294 GALRSETGG----LSGKPLRDLSTQTIREMYALTQGRIPIIGVGGVSSGQDALEKIQAGA 349 G + S GG S P+ L+ + ++ + GGV G D L+ + GA Sbjct: 367 GVVLSNHGGRQLDFSRAPIEVLAETMPILEQRNLKDKLEVFVDGGVRRGTDVLKALCLGA 426 Query: 350 SLVQLYTALIFLG--------PPVVVRVKRELEALLKERGFTTVTDA 388 V L ++ + ++ E+E ++ G T++ + Sbjct: 427 KGVGLGRPFLYANSCYGRNGVEKAIEILRDEIEMSMRLLGVTSIAEL 473 >3L5A-A nrPDB Length = 419 Score = 32.8 bits (73), Expect = 0.27, Method: Composition-based stats. Identities = 16/60 (26%), Positives = 27/60 (45%), Gaps = 8/60 (13%) Query: 319 MYALTQGRIPIIGVGGV---SSGQDALEKIQAGASLVQLYTALIFLGPPVVVRVKRELEA 375 +Y GRIP+I GG+ S DAL+ A +V + + + P V ++ + Sbjct: 311 VYEHLAGRIPLIASGGINSPESALDALQH----ADMVGMSSPFVTE-PDFVHKLAEQRPH 365 >4EVZ-A nrPDB Length = 258 Score = 32.4 bits (72), Expect = 0.36, Method: Composition-based stats. Identities = 16/64 (25%), Positives = 28/64 (43%), Gaps = 3/64 (4%) Query: 309 RDLSTQTIREMYALTQGRIPIIGVGGVSSGQDALEKIQAGASLVQLYTALIFLGPPVVVR 368 R+ + + IP+ GG+ S +DA ++AGA V + TA + P ++ Sbjct: 59 RETMLEVVERTAEQVF--IPLTVGGGIRSVEDASRLLRAGADKVSINTAAVKN-PELITE 115 Query: 369 VKRE 372 E Sbjct: 116 AAEE 119 >1JCN-A nrPDB Length = 514 Score = 32.4 bits (72), Expect = 0.37, Method: Composition-based stats. Identities = 17/82 (20%), Positives = 32/82 (39%), Gaps = 3/82 (3%) Query: 305 GKPLRDLSTQTIREMYALTQGRIPIIGVGGVSSGQDALEKIQAGASLVQLYTALIFLGPP 364 G+P + + + E +PII GG+ + ++ + GAS V + + L Sbjct: 340 GRP-QGTAVYKVAEYARRFG--VPIIADGGIQTVGHVVKALALGASTVMMGSLLAATTEA 396 Query: 365 VVVRVKRELEALLKERGFTTVT 386 + L K RG ++ Sbjct: 397 PGEYFFSDGVRLKKYRGMGSLD 418 >4J9J-A nrPDB Length = 246 Score = 32.4 bits (72), Expect = 0.38, Method: Composition-based stats. Identities = 14/43 (32%), Positives = 22/43 (51%), Gaps = 1/43 (2%) Query: 327 IPIIGVGGVSSGQDALEKIQAGASLVQLYTALIFLGPPVVVRV 369 +PII GG + LE AGA V + TA + P ++ ++ Sbjct: 101 LPIIASGGAGKMEHFLEAFLAGADKVSINTAAVEN-PSLITQI 142 >4DGS-A nrPDB Length = 340 Score = 32.0 bits (71), Expect = 0.40, Method: Composition-based stats. Identities = 15/45 (33%), Positives = 17/45 (37%), Gaps = 3/45 (6%) Query: 17 LGGGGLLFTSYLTATG--DDHFYAEYLMPGLQRLLDPE-SAHRLA 58 LG L F S L D E +MP + L S HRL Sbjct: 13 LGTENLYFQSMLEFRNVKPDLLLVEPMMPFVMDELQRNYSVHRLY 57 >1QCW-A nrPDB Length = 410 Score = 32.0 bits (71), Expect = 0.43, Method: Composition-based stats. Identities = 43/227 (18%), Positives = 84/227 (37%), Gaps = 34/227 (14%) Query: 186 TSEDAAADYAEGVRTLGPLADYLVVNVSSPNTAGLRSLQGKTELRHLLSK---------- 235 + D + V LG A ++ V+ L + +L+ +K Sbjct: 156 SDRKITDDLVKNVEKLGVKALFVTVD-----APSLGQKEKDMKLKFSNTKAGFKAMKKTN 210 Query: 236 VLQERDALKGTRKPAVLVKIAPDLTAQDKEDIAS-VARELGIDGLIVTNTTV-SRPVGLQ 293 V + + A + K I P LT +D E++ + I G+ T + + +G+ Sbjct: 211 VEESQGASRALSK-----FIDPSLTWKDIEELKKKTKLPIVIKGVQRTEDVIKAAEIGVS 265 Query: 294 GALRSETGG----LSGKPLRDLSTQTIREMYALTQGRIPIIGVGGVSSGQDALEKIQAGA 349 G + S GG S P+ L+ + ++ + GGV G D L+ + GA Sbjct: 266 GVVLSNHGGRQLDFSRAPIEVLAETMPILEQRNLKDKLEVFVDGGVRRGTDVLKALCLGA 325 Query: 350 SLVQLYTALIFLG--------PPVVVRVKRELEALLKERGFTTVTDA 388 V L ++ + ++ E+E ++ G T++ + Sbjct: 326 KGVGLGRPFLYANSCYGRNGVEKAIEILRDEIEMSMRLLGVTSIAEL 372 >5GVH-A nrPDB Length = 314 Score = 32.0 bits (71), Expect = 0.44, Method: Composition-based stats. Identities = 35/152 (23%), Positives = 64/152 (42%), Gaps = 26/152 (17%) Query: 228 ELRHLLSKVLQERDALKGTRKPAV------LVKIAPDLTAQDKEDIA--------SVARE 273 +LR +S++ Q+ D G V LVK+ ++K + RE Sbjct: 52 DLRKAISELRQKTDKPFGVNIILVSPWADDLVKV----CIEEKVPVVTFGAGNPTKYIRE 107 Query: 274 LGIDGL----IVTNTTVSRPVGLQGALRSETGGL-SGKPLRDLST-QTIREMYALTQGRI 327 L +G +V + +++R V GA G+ SG + +++T + ++ I Sbjct: 108 LKENGTKVIPVVASDSLARMVERAGADAVIAEGMESGGHIGEVTTFVLVNKVSRSVN--I 165 Query: 328 PIIGVGGVSSGQDALEKIQAGASLVQLYTALI 359 P+I GG++ G+ GA VQ+ T + Sbjct: 166 PVIAAGGIADGRGMAAAFALGAEAVQMGTRFV 197 >5D2Y-A nrPDB Length = 264 Score = 31.6 bits (70), Expect = 0.55, Method: Composition-based stats. Identities = 14/61 (22%), Positives = 27/61 (44%), Gaps = 3/61 (4%) Query: 309 RDLSTQTIREMYALTQGRIPIIGVGGVSSGQDALEKIQAGASLVQLYTALIFLGPPVVVR 368 R + + ++ IP GG+ + A E I GA V++ TA + P ++ + Sbjct: 60 RKTMLELVEKVAEQID--IPFTVGGGIHDFETASELILRGADKVEINTAAVEN-PSLITQ 116 Query: 369 V 369 + Sbjct: 117 I 117 >3PZL-A nrPDB Length = 313 Score = 31.6 bits (70), Expect = 0.56, Method: Composition-based stats. Identities = 31/125 (24%), Positives = 52/125 (41%), Gaps = 10/125 (8%) Query: 60 RVTSLGL--LPRATFQDSDMLEVKVLGHKFRNPVGIAA-GFDKNGEAVDGLYKLGFGFVE 116 R+TS+G+ + R F+D D +V F + + G DK E VD + + V+ Sbjct: 175 RITSIGIRSVSREEFEDPDFRKVS-----FISSFDVKKNGIDKYIEEVDRKSRRVYISVD 229 Query: 117 VGSVTPQ--PQEGNPRPRVFRLPEDQAVINRYGFNSHGLSVVEHRLRARQQKQAQLTADG 174 + + P P G P P + + +I R + + G +VE + L A Sbjct: 230 MDGIDPAYAPAVGTPEPFGLADTDVRRLIERLSYKAVGFDIVEFSPLYDNGNTSMLAAKL 289 Query: 175 LPLGI 179 L + I Sbjct: 290 LQVFI 294 >4IQL-A nrPDB Length = 333 Score = 31.3 bits (69), Expect = 0.74, Method: Composition-based stats. Identities = 29/149 (19%), Positives = 52/149 (34%), Gaps = 22/149 (14%) Query: 229 LRHLLSKVLQERDALKGTRKPAVLVKIAPDLTAQDKEDIASVARELGIDGL--------- 279 L H + D G P + ++ + +E + V G + Sbjct: 70 LEHHIRSCKAATDKPFGVNVPLLYPEMDKIMEIIMREHVPVVVTSAGSPKVWTAKLKAAG 129 Query: 280 -----IVTNTTVSRPVGLQGALRS-----ETGGLSGKPLRDLSTQTIREMYALTQGRIPI 329 +V++ T +R G E GG +G+ + I E+ IP+ Sbjct: 130 SKVIHVVSSATFARKSEAAGVDAIVAEGFEAGGHNGRE-ETTTLCLIPEVVDAVN--IPV 186 Query: 330 IGVGGVSSGQDALEKIQAGASLVQLYTAL 358 + GG++SG+ + GA VQ+ T Sbjct: 187 VAAGGIASGRAVAAALALGADAVQVGTRF 215 >1EEP-A nrPDB Length = 404 Score = 31.3 bits (69), Expect = 0.74, Method: Composition-based stats. Identities = 13/44 (29%), Positives = 19/44 (43%), Gaps = 1/44 (2%) Query: 316 IREMYALTQG-RIPIIGVGGVSSGQDALEKIQAGASLVQLYTAL 358 I ++Y I II GG+ D ++ I AGA V + Sbjct: 245 ICDVYEACNNTNICIIADGGIRFSGDVVKAIAAGADSVMIGNLF 288 >3IPM-H nrPDB Length = 217 Score = 31.3 bits (69), Expect = 0.79, Method: Composition-based stats. Identities = 15/65 (23%), Positives = 26/65 (40%), Gaps = 1/65 (1%) Query: 332 VGGVSSGQDALEKIQAGASLVQLYTALIFLGPPVVVRVKRELEALLK-ERGFTTVTDAIG 390 VGG+ + AG S+ +Y + P V ++ + + + G V AI Sbjct: 109 VGGIDTAPHVFSIDAAGGSVEDIYASTGSGSPFVYGVLESQYSEKMTVDEGVDLVIRAIS 168 Query: 391 ADHRR 395 A +R Sbjct: 169 AAKQR 173 >3O15-A nrPDB Length = 235 Score = 31.3 bits (69), Expect = 0.81, Method: Composition-based stats. Identities = 18/53 (33%), Positives = 26/53 (49%), Gaps = 2/53 (3%) Query: 321 ALTQGRIPIIGVGGVSSGQDALEKIQAGASLVQLYTAL-IFLGPPVVVRVKRE 372 IPI+G+GG+ + +A IQAGA V + +A+ P R RE Sbjct: 175 RRQGISIPIVGIGGI-TIDNAAPVIQAGADGVSMISAISQAEDPESAARKFRE 226 >1VH7-A nrPDB Length = 265 Score = 31.3 bits (69), Expect = 0.85, Method: Composition-based stats. Identities = 14/61 (22%), Positives = 26/61 (42%), Gaps = 3/61 (4%) Query: 309 RDLSTQTIREMYALTQGRIPIIGVGGVSSGQDALEKIQAGASLVQLYTALIFLGPPVVVR 368 R + + ++ IP GG+ + A E I GA V + TA + P ++ + Sbjct: 61 RKTMLELVEKVAEQID--IPFTVGGGIHDFETASELILRGADKVSINTAAVEN-PSLITQ 117 Query: 369 V 369 + Sbjct: 118 I 118 >4JDY-A nrPDB Length = 264 Score = 30.9 bits (68), Expect = 0.92, Method: Composition-based stats. Identities = 11/51 (21%), Positives = 24/51 (47%) Query: 314 QTIREMYALTQGRIPIIGVGGVSSGQDALEKIQAGASLVQLYTALIFLGPP 364 + + E+ + + + GG+++ DA +Q GA V + + + G P Sbjct: 189 ELVAEVARAGKLPVTLFTAGGIATPADAAMMMQLGAEGVFVGSGIFKSGAP 239 >4LC4-A nrPDB Length = 352 Score = 30.9 bits (68), Expect = 1.0, Method: Composition-based stats. Identities = 12/62 (19%), Positives = 17/62 (27%), Gaps = 15/62 (24%) Query: 17 LGGGGLLFTSY---------------LTATGDDHFYAEYLMPGLQRLLDPESAHRLAVRV 61 LG L F S ++ D + L+D E A L R+ Sbjct: 13 LGTENLYFQSMTRFDVLTVGNAIVDIISRCNDQFLIDNQITKAAMNLIDAERAELLYSRM 72 Query: 62 TS 63 Sbjct: 73 GP 74 >1H5Y-A nrPDB Length = 253 Score = 30.9 bits (68), Expect = 1.0, Method: Composition-based stats. Identities = 18/47 (38%), Positives = 26/47 (55%), Gaps = 1/47 (2%) Query: 326 RIPIIGVGGVSSGQDALEKIQAGASLVQLYTALIFLGPPVVVRVKRE 372 IP++ GGV S +DA +AGA V + TA + P +V + RE Sbjct: 77 SIPVLVGGGVRSLEDATTLFRAGADKVSVNTAAVRN-PQLVALLARE 122 >6HYE-A nrPDB Length = 314 Score = 30.5 bits (67), Expect = 1.2, Method: Composition-based stats. Identities = 14/56 (25%), Positives = 29/56 (51%), Gaps = 3/56 (5%) Query: 325 GRIPI--IGVGGVSSGQDALEKIQAGASLVQLYTALIFLGPPVVVRVKRELEALLK 378 GR+P+ GG+++ DA +Q G V + + +F GP +++ ++A+ Sbjct: 224 GRVPVVQFASGGITTPADAALMMQLGCDGVFVGSE-VFDGPDPFKKLRSIVQAVQH 278 >4FXS-A nrPDB Length = 496 Score = 30.5 bits (67), Expect = 1.2, Method: Composition-based stats. Identities = 12/32 (37%), Positives = 17/32 (53%) Query: 327 IPIIGVGGVSSGQDALEKIQAGASLVQLYTAL 358 IP+I GG+ D + I AGAS V + + Sbjct: 335 IPVIADGGIRFSGDISKAIAAGASCVMVGSMF 366 >1KA9-F nrPDB Length = 252 Score = 30.5 bits (67), Expect = 1.3, Method: Composition-based stats. Identities = 15/63 (23%), Positives = 26/63 (41%), Gaps = 7/63 (11%) Query: 313 TQTIREMYALTQGRIPIIGVGGVSSGQDALEKIQAGASLVQLYTALIFLGPPVVVRVKRE 372 + + IP+ GGV S +DA + + +GA V + +A + + RE Sbjct: 64 LDVVARVAERVF--IPLTVGGGVRSLEDARKLLLSGADKVSVNSAAVRR-----PELIRE 116 Query: 373 LEA 375 L Sbjct: 117 LAD 119 >4FEZ-A nrPDB Length = 388 Score = 30.5 bits (67), Expect = 1.4, Method: Composition-based stats. Identities = 12/32 (37%), Positives = 17/32 (53%) Query: 327 IPIIGVGGVSSGQDALEKIQAGASLVQLYTAL 358 IP+I GG+ D + I AGAS V + + Sbjct: 234 IPVIADGGIRFSGDISKAIAAGASCVMVGSMF 265 >2PKQ-O nrPDB Length = 368 Score = 30.5 bits (67), Expect = 1.4, Method: Composition-based stats. Identities = 21/91 (23%), Positives = 36/91 (39%), Gaps = 1/91 (1%) Query: 263 DKEDIASVARELGIDGLIVTNTTVSRPVGLQGALRSETGGLSGKPLRDLS-TQTIREMYA 321 D + L+ ++ + + +ET + GKP++ +S ++ +A Sbjct: 29 DVVVVNDSGGVKSATHLLKYDSILGTFKADVKIIDNETFSIDGKPIKVVSNRDPLKLPWA 88 Query: 322 LTQGRIPIIGVGGVSSGQDALEKIQAGASLV 352 I I G G G A + IQAGA V Sbjct: 89 ELGIDIVIEGTGVFVDGPGAGKHIQAGAKKV 119 >5DBT-A nrPDB Length = 204 Score = 30.1 bits (66), Expect = 1.6, Method: Composition-based stats. Identities = 38/179 (21%), Positives = 62/179 (34%), Gaps = 42/179 (23%) Query: 174 GLPLGINLGKNK--TSEDAAADYAEGVRTLGPLADYLVVNVSSPNTAGLRSLQGKTELRH 231 G PLG N K ++DA ++ A+ + + + N L Sbjct: 65 GFPLGANTPAVKAFETKDAISNGADEIDMVINIGALKTGN-------------YDLVLED 111 Query: 232 LLSKVLQERDALKGTRKPAVLVKIAPDLTAQDKEDIASVARELGIDGLIVTNTTVSRPVG 291 + + V D L A L LT +K +++E G D + T+T S Sbjct: 112 IKAVVAASGDKLVKVIIEACL------LTDDEKVKACQLSQEAGAD-YVKTSTGFST--- 161 Query: 292 LQGALRSETGGLSGKPLRDLSTQTIREMYALTQGRIPIIGVGGVSSGQDALEKIQAGAS 350 G + D++ M + + GG S +DA+ I+AGAS Sbjct: 162 ------------GGATVADVAL-----MRKTVGPDMGVKASGGARSYEDAIAFIEAGAS 203 >1UB3-A nrPDB Length = 220 Score = 30.1 bits (66), Expect = 1.6, Method: Composition-based stats. Identities = 12/46 (26%), Positives = 23/46 (50%) Query: 312 STQTIREMYALTQGRIPIIGVGGVSSGQDALEKIQAGASLVQLYTA 357 S + + + + QGR + GG+ + AL ++AGAS + + Sbjct: 162 SLEDVALLVRVAQGRAQVKAAGGIRDRETALRMLKAGASRLGTSSG 207 >3TDN-A nrPDB Length = 247 Score = 29.7 bits (65), Expect = 2.1, Method: Composition-based stats. Identities = 13/43 (30%), Positives = 21/43 (48%), Gaps = 1/43 (2%) Query: 327 IPIIGVGGVSSGQDALEKIQAGASLVQLYTALIFLGPPVVVRV 369 +PII GG + LE GA V + TA + P ++ ++ Sbjct: 80 LPIIASGGAGKMEHFLEAFLRGADKVSINTAAVEN-PSLITQI 121 Score = 29.7 bits (65), Expect = 2.1, Method: Composition-based stats. Identities = 13/43 (30%), Positives = 21/43 (48%), Gaps = 1/43 (2%) Query: 327 IPIIGVGGVSSGQDALEKIQAGASLVQLYTALIFLGPPVVVRV 369 +PII GG + LE GA V + TA + P ++ ++ Sbjct: 201 LPIIASGGAGKMEHFLEAFLRGADKVSINTAAVEN-PSLITQI 242 >3TDM-A nrPDB Length = 126 Score = 29.7 bits (65), Expect = 2.1, Method: Composition-based stats. Identities = 13/43 (30%), Positives = 21/43 (48%), Gaps = 1/43 (2%) Query: 327 IPIIGVGGVSSGQDALEKIQAGASLVQLYTALIFLGPPVVVRV 369 +PII GG + LE GA V + TA + P ++ ++ Sbjct: 80 LPIIASGGAGKMEHFLEAFLRGADKVSINTAAVEN-PSLITQI 121 >3DH7-A nrPDB Length = 332 Score = 29.7 bits (65), Expect = 2.1, Method: Composition-based stats. Identities = 29/188 (15%), Positives = 55/188 (29%), Gaps = 15/188 (7%) Query: 154 SVVEHRLRARQQKQAQLTADGLPLGINLGKNKTSEDAAADYAEGVRTLGPLADYLVVNVS 213 ++ R A + + + A L NLG + D V L A VN Sbjct: 97 RILLERPEALRSFRVRKVAPKALLIANLGLAQLRRYGRDDLLRLVEMLEADALAFHVN-- 154 Query: 214 SPNTAGLRSLQ-GKTELRHLLSKVLQERDALKGTRKPAVLVKIAPDLTAQDKEDIASVAR 272 ++Q G T+ R L+ ++ + V ++ + ++ + Sbjct: 155 ----PLQEAVQRGDTDFRGLVERLAELLPLPFPVMVKEVGHGLSREAALALRDLPLAAVD 210 Query: 273 ELGIDGLIVTNTTVSRPVGLQGALRSETGGLSGKPLRDLSTQTIREMYALTQGRIPIIGV 332 G G G G+ + + +P++ Sbjct: 211 VAGAGGTSWARVEEWVRFGEVRHPELCEIGI------PTARAILE--VREVLPHLPLVAS 262 Query: 333 GGVSSGQD 340 GGV +G D Sbjct: 263 GGVYTGTD 270 >6I0M-A nrPDB Length = 517 Score = 29.7 bits (65), Expect = 2.2, Method: Composition-based stats. Identities = 16/82 (19%), Positives = 31/82 (37%), Gaps = 3/82 (3%) Query: 305 GKPLRDLSTQTIREMYALTQGRIPIIGVGGVSSGQDALEKIQAGASLVQLYTALIFLGPP 364 G+P + + + E +P+I GG+ + + + GAS V + + L Sbjct: 343 GRP-QATAVYKVSEYARRFG--VPVIADGGIQNVGHIAKALALGASTVMMGSLLAATTEA 399 Query: 365 VVVRVKRELEALLKERGFTTVT 386 + L K RG ++ Sbjct: 400 PGEYFFSDGIRLKKYRGMGSLD 421 >2ZBT-A nrPDB Length = 297 Score = 29.7 bits (65), Expect = 2.2, Method: Composition-based stats. Identities = 13/83 (15%), Positives = 28/83 (33%), Gaps = 20/83 (24%) Query: 325 GRIPI--IGVGGVSSGQDALEKIQAGASLVQLYTAL------------------IFLGPP 364 GR+P+ GG+++ DA + G V + + + + P Sbjct: 206 GRLPVVNFAAGGIATPADAALMMHLGMDGVFVGSGIFKSGDPRKRARAIVRAVAHYNDPE 265 Query: 365 VVVRVKRELEALLKERGFTTVTD 387 V+ V +L + + + Sbjct: 266 VLAEVSEDLGEPMVGINLDQLKE 288 >2ISS-A nrPDB Length = 313 Score = 29.7 bits (65), Expect = 2.2, Method: Composition-based stats. Identities = 14/48 (29%), Positives = 25/48 (52%), Gaps = 4/48 (8%) Query: 313 TQTIREMYALTQGRIPI--IGVGGVSSGQDALEKIQAGASLVQLYTAL 358 + +RE+ L GR+P+ GGV++ DA + GA V + + + Sbjct: 214 VELLREVKRL--GRLPVVNFAAGGVATPADAALMMMLGADGVFVGSGI 259 >1YDN-A nrPDB Length = 295 Score = 29.7 bits (65), Expect = 2.2, Method: Composition-based stats. Identities = 36/231 (15%), Positives = 69/231 (29%), Gaps = 24/231 (10%) Query: 104 VDGLYKLGFGFVEVGS-VTPQ--PQEGNPRPRVFRLPEDQAVINRYGFNSH-GLSVVEHR 159 ++ L G+ +E S V+P+ PQ + R + + V + G Sbjct: 32 INRLSDCGYARIEATSFVSPKWVPQLADSREVMAGIRRADGVRYSVLVPNMKGYEAAAAA 91 Query: 160 LRARQQKQAQLTADGLPLGINLGKNKTSEDAAADYAEGVRTLGPLADYLVVNVSSPNTAG 219 + IN ++ E + + + Y+ V P Sbjct: 92 HADEIAVFISASEGFSKANINCTIAESIERLSPVIGAAINDGLAIRGYVSCVVECP---- 147 Query: 220 LRSLQGKTELRHLLSKVLQERDALKGTRKPAVLVKI---APDLTAQDKEDIASVARELGI 276 + + E+ G + ++ I PD A + + ++A + Sbjct: 148 -----YDGPVTPQAVASVTEQLFSLGCHEVSLGDTIGRGTPDTVAAMLDAVLAIAPAHSL 202 Query: 277 DG-------LIVTNTTVSRPVGLQGALRSETGGLSGKPLRDLSTQTIREMY 320 G + N VS GL+ S GGL G P + + + Sbjct: 203 AGHYHDTGGRALDNIRVSLEKGLRVFDAS-VGGLGGCPFAPGAKGNVDTVA 252 >2NV2-A nrPDB Length = 294 Score = 29.7 bits (65), Expect = 2.3, Method: Composition-based stats. Identities = 13/52 (25%), Positives = 23/52 (44%), Gaps = 3/52 (5%) Query: 324 QGRIPI--IGVGGVSSGQDALEKIQAGASLVQLYTALIFLG-PPVVVRVKRE 372 G++P+ GGV++ DA +Q GA V + + + P + E Sbjct: 202 DGKLPVVNFAAGGVATPADAALMMQLGADGVFVGSGIFKSDNPAKFAKAIVE 253 >5UPU-A nrPDB Length = 407 Score = 29.7 bits (65), Expect = 2.4, Method: Composition-based stats. Identities = 13/49 (26%), Positives = 21/49 (42%) Query: 310 DLSTQTIREMYALTQGRIPIIGVGGVSSGQDALEKIQAGASLVQLYTAL 358 T + + A +P+I GG+ D + + AGAS L + L Sbjct: 230 PQITAILEAVAACRPAGVPVIADGGLQYSGDIAKALAAGASTAMLGSLL 278 >5MHL-A nrPDB Length = 738 Score = 29.7 bits (65), Expect = 2.5, Method: Composition-based stats. Identities = 33/140 (23%), Positives = 52/140 (37%), Gaps = 14/140 (10%) Query: 267 IASVARELGIDGLIVTN--TTVSRPVGLQGALRSETGGLSGKPLRDLSTQTIREM--YAL 322 + R LGI IVTN + LQ + E G L S + Sbjct: 328 FNTFLRCLGIPARIVTNYFSAHDNDANLQMDIFLEEDGNVNSKLTKDSVWNYHCWNEAWM 387 Query: 323 TQGRIPIIGVGG---VSSG--QDALEKIQAGASLVQ----LYTALIFLGPPVVVRVKREL 373 T+ +P+ G GG V S +++ + G + VQ + F P V V +L Sbjct: 388 TRPDLPV-GFGGWQAVDSTPQENSDGMYRCGPASVQAIKHGHVCFQFDAPFVFAEVNSDL 446 Query: 374 EALLKERGFTTVTDAIGADH 393 + ++ T V + + A H Sbjct: 447 IYITAKKDGTHVVENVDATH 466 >5J5Z-A nrPDB Length = 496 Score = 29.7 bits (65), Expect = 2.5, Method: Composition-based stats. Identities = 12/65 (18%), Positives = 29/65 (44%), Gaps = 5/65 (7%) Query: 321 ALTQGRIPIIGVG--GVSSGQDALEKIQAGASLVQLYTALIFLGPPVVVRVKRELEALLK 378 ++ +IG G GV G +++ GA + + G + + + + + +L+ Sbjct: 197 KKVPEKMVVIGAGVIGVELG-SVWQRL--GADVTAVEFLGHVGGVGIDMEISKNFQRILQ 253 Query: 379 ERGFT 383 ++GF Sbjct: 254 KQGFK 258 >6NKE-A nrPDB Length = 252 Score = 29.3 bits (64), Expect = 2.7, Method: Composition-based stats. Identities = 17/53 (32%), Positives = 27/53 (50%), Gaps = 3/53 (5%) Query: 304 SGKPLRDLSTQTIREMYALTQGRIPIIGVGGVSSGQDALEKIQAGASLVQLYT 356 SG P R +S TI Y ++ IP+I GG+ + A+ AGA ++ + Sbjct: 175 SGAP-RPVSEDTIS--YVKSKINIPLIVGGGIRDPETAMRIALAGADMIVTGS 224 >1P0K-A nrPDB Length = 349 Score = 29.3 bits (64), Expect = 2.8, Method: Composition-based stats. Identities = 39/223 (17%), Positives = 73/223 (32%), Gaps = 31/223 (13%) Query: 177 LGINLGKNKTSEDAAADYAEGVRTLGPLADYLVVNVSSPNTAGLRSLQGKTELRHLLSKV 236 + NLG SE AA E V +G A + +NV ++ + R + Sbjct: 119 IFANLG----SEATAAQAKEAVEMIGANALQIHLNV-------IQEIVMPEGDRSFSGAL 167 Query: 237 LQERDALKGTRKPAVLVKIAPDLT---AQDKEDIASVARELGIDGLIVTNTTVSRPVGLQ 293 + P ++ ++ ++ A + + A ++G G + + Q Sbjct: 168 KRIEQICSRVSVPVIVKEVGFGMSKASAGKLYEAGAAAVDIGGYGGTNFSKIENLRRQRQ 227 Query: 294 GALRSETGGLSGKPLRDLSTQTIREMYALTQGRIPIIGVGGVSSGQDALEKIQAGASLVQ 353 + + G +ST +I GG+ D + I GAS Sbjct: 228 ISFFNSWG---------ISTAASLAEIRSEFPASTMIASGGLQDALDVAKAIALGASCTG 278 Query: 354 LY----TALIFLGP----PVVVRVKRELEALLKERGFTTVTDA 388 + AL G + + EL+ ++ G T+ D Sbjct: 279 MAGHFLKALTDSGEEGLLEEIQLILEELKLIMTVLGARTIADL 321 >4N6F-A nrPDB Length = 256 Score = 29.3 bits (64), Expect = 2.9, Method: Composition-based stats. Identities = 16/52 (30%), Positives = 26/52 (50%), Gaps = 2/52 (3%) Query: 314 QTIREMYALTQGRIPIIGVGGVSSGQDALEKIQAGASLVQLYTALIFLGPPV 365 IRE+ IP++ GG+ S + E ++ GAS + TAL+ P+ Sbjct: 178 AAIRELIEQIG--IPVVVEGGIGSARHVAEAMELGASATLVNTALVRAESPL 227 >3NDO-A nrPDB Length = 231 Score = 29.3 bits (64), Expect = 3.0, Method: Composition-based stats. Identities = 10/39 (25%), Positives = 18/39 (46%) Query: 312 STQTIREMYALTQGRIPIIGVGGVSSGQDALEKIQAGAS 350 S Q + M R+ + GG+ + + A + AGA+ Sbjct: 176 SVQAVEIMARTVGERLGVKASGGIRTAEQAAAMLDAGAT 214 >2W6R-A nrPDB Length = 266 Score = 29.3 bits (64), Expect = 3.1, Method: Composition-based stats. Identities = 17/55 (30%), Positives = 23/55 (41%), Gaps = 5/55 (9%) Query: 327 IPIIGVGGVSSGQDALEKIQAGASLVQLYTALIFLGPPVVVRVKRELEALLKERG 381 +PII GG + LE AGA + F + REL+ LK+ G Sbjct: 75 LPIIASGGAGKMEHFLEAFLAGADKALAASVFHFREIDM-----RELKEYLKKHG 124 >4FIQ-A nrPDB Length = 335 Score = 29.3 bits (64), Expect = 3.1, Method: Composition-based stats. Identities = 14/82 (17%), Positives = 29/82 (35%), Gaps = 20/82 (24%) Query: 325 GRIPI--IGVGGVSSGQDALEKIQAGASLVQLYTA------------------LIFLGPP 364 GR+P+ GGV++ DA + G V + + + P Sbjct: 246 GRLPVVNFAAGGVATPADAALMMAMGMDGVFVGSGIFKSSNPPKMARAIVEAVNHWDEPD 305 Query: 365 VVVRVKRELEALLKERGFTTVT 386 V+ + RE+ ++ + + Sbjct: 306 VLAEISREIGEPMRGQAIEELQ 327 >5Z9Y-A nrPDB Length = 252 Score = 29.3 bits (64), Expect = 3.3, Method: Composition-based stats. Identities = 33/149 (22%), Positives = 54/149 (36%), Gaps = 15/149 (10%) Query: 215 PNTAGLRSLQGKTELRHLLSKVLQERDALKGTRKPAVLVKIAPDLTA--QDKEDIASVAR 272 PNTAG RS VL + A + V +++ D D ++ A Sbjct: 70 PNTAGSRSAAE---------AVLTAQLAREALNTNWVKLEVIADERTLWPDAVELVRAAE 120 Query: 273 ELGIDGLIVTNTTVSRPVGLQGALRSETGG---LSGKPLRDLSTQTIREMYALTQG-RIP 328 +L DG +V T PV + + L L + + G R+P Sbjct: 121 QLVDDGFVVLPYTTDDPVLARRLEDTGCAAVMPLGSPIGTGLGIANPHNIEMIVAGARVP 180 Query: 329 IIGVGGVSSGQDALEKIQAGASLVQLYTA 357 ++ G+ + DA ++ G V L +A Sbjct: 181 VVLDAGIGTASDAALAMELGCDAVLLASA 209 >3SR7-A nrPDB Length = 365 Score = 29.3 bits (64), Expect = 3.4, Method: Composition-based stats. Identities = 38/190 (20%), Positives = 72/190 (37%), Gaps = 26/190 (13%) Query: 182 GKNKTSEDAAADYAEGVRTLGPLADYLVVN--VSSPNTAGLRSLQGKTELRHLLSKV--- 236 G T+ D + V+ P L N + P AGL++++ +L+ L +V Sbjct: 122 GSYSTALKNPDDTSYQVKKSRPHL-LLATNIGLDKPYQAGLQAVR---DLQPLFLQVHIN 177 Query: 237 -LQERDALKGTRKPAVLVKIAPDLTAQDKEDIASVARELGIDGLIVTNTTVSRPVGLQGA 295 +QE +G R+ K D K + + +E+G G+ V + +G++ Sbjct: 178 LMQELLMPEGEREFRSWKKHLSDYAK--KLQLPFILKEVGF-GMDVKTIQTAIDLGVKTV 234 Query: 296 LRSETGGLSGKPLRDL-------------STQTIREMYALTQGRIPIIGVGGVSSGQDAL 342 S GG S + + +T + ++ I+ GG+ D + Sbjct: 235 DISGRGGTSFAYIENRRGGNRSYLNQWGQTTAQVLLNAQPLMDKVEILASGGIRHPLDII 294 Query: 343 EKIQAGASLV 352 + + GA V Sbjct: 295 KALVLGAKAV 304 >4PFI-A nrPDB Length = 344 Score = 28.9 bits (63), Expect = 3.6, Method: Composition-based stats. Identities = 15/100 (15%), Positives = 27/100 (27%), Gaps = 15/100 (15%) Query: 17 LGGGGLLFTSYLTATGDDHFYAEYLMPGLQRLLDPESAHRLAVRVT-----------SLG 65 LG L F S +T + ++ H A + + Sbjct: 13 LGTENLYFQSMAQSTANGKPEYPVTWRFALEEIEGSVQHLYAQQFREQVEALSGGRIEVD 72 Query: 66 LLPRATFQDSDML----EVKVLGHKFRNPVGIAAGFDKNG 101 + P + S L + F +P +A + G Sbjct: 73 VFPYGSLGTSAQLTELTRNGSVNLAFASPGHLADTVPETG 112 >3FFS-A nrPDB Length = 400 Score = 28.9 bits (63), Expect = 4.0, Method: Composition-based stats. Identities = 21/94 (22%), Positives = 34/94 (36%), Gaps = 10/94 (10%) Query: 265 EDIASVARELGIDGLIVTNTTVSRPVGLQGALRSETGGLSGKPLRDLSTQTIREMYALTQ 324 E+ E G DG+ V G R G+ + + + + + Sbjct: 195 EEATKELIENGADGI-----KVGIGPGSICTTR-IVAGVGVPQI--TAIEKCSSVASKFG 246 Query: 325 GRIPIIGVGGVSSGQDALEKIQAGASLVQLYTAL 358 IPII GG+ D + + GAS V + + L Sbjct: 247 --IPIIADGGIRYSGDIGKALAVGASSVMIGSIL 278 >1PFK-A nrPDB Length = 320 Score = 28.9 bits (63), Expect = 4.0, Method: Composition-based stats. Identities = 9/27 (33%), Positives = 17/27 (62%) Query: 1 MAWRQLRKRALDAVIILGGGGLLFTSY 27 +A L+KR +DA++++GG G + Sbjct: 85 VAIENLKKRGIDALVVIGGDGSYMGAM 111 >5LNT-A nrPDB Length = 316 Score = 28.9 bits (63), Expect = 4.1, Method: Composition-based stats. Identities = 14/43 (32%), Positives = 22/43 (51%), Gaps = 2/43 (4%) Query: 325 GRIPI--IGVGGVSSGQDALEKIQAGASLVQLYTALIFLGPPV 365 GR+P+ GGV++ DA +Q G V + + + G PV Sbjct: 220 GRLPVVQFAAGGVATPADAALMMQLGCDGVFVGSGVFKSGDPV 262 >3R12-A nrPDB Length = 260 Score = 28.6 bits (62), Expect = 4.6, Method: Composition-based stats. Identities = 13/65 (20%), Positives = 28/65 (43%), Gaps = 6/65 (9%) Query: 286 VSRPVGLQGALRSETG-GLSGKPLRDLSTQTIREMYALTQGRIPIIGVGGVSSGQDALEK 344 V + +++ TG G G + + + M + + + GG+ + +DA++ Sbjct: 180 VISKLAGAHFVKTSTGFGTGGA-----TAEDVHLMKWIVGDEMGVKASGGIRTFEDAVKM 234 Query: 345 IQAGA 349 I GA Sbjct: 235 IMYGA 239 >4QJ1-A nrPDB Length = 361 Score = 28.6 bits (62), Expect = 4.7, Method: Composition-based stats. Identities = 21/94 (22%), Positives = 34/94 (36%), Gaps = 10/94 (10%) Query: 265 EDIASVARELGIDGLIVTNTTVSRPVGLQGALRSETGGLSGKPLRDLSTQTIREMYALTQ 324 E+ E G DG+ V G R G+ + + + + + Sbjct: 156 EEATKELIENGADGI-----KVGIGPGSICTTR-IVAGVGVPQI--TAIEKCSSVASKFG 207 Query: 325 GRIPIIGVGGVSSGQDALEKIQAGASLVQLYTAL 358 IPII GG+ D + + GAS V + + L Sbjct: 208 --IPIIADGGIRYSGDIGKALAVGASSVMIGSIL 239 >3TSB-A nrPDB Length = 511 Score = 28.6 bits (62), Expect = 4.8, Method: Composition-based stats. Identities = 11/32 (34%), Positives = 18/32 (56%) Query: 327 IPIIGVGGVSSGQDALEKIQAGASLVQLYTAL 358 IP+I GG+ D ++ + AGA +V L + Sbjct: 360 IPVIADGGIKYSGDMVKALAAGAHVVMLGSMF 391 >3PUD-A nrPDB Length = 291 Score = 28.6 bits (62), Expect = 5.0, Method: Composition-based stats. Identities = 15/39 (38%), Positives = 23/39 (58%) Query: 313 TQTIREMYALTQGRIPIIGVGGVSSGQDALEKIQAGASL 351 TQ I+E+ + RIPII G +S ++A+E +A L Sbjct: 57 TQVIKEIIRVANKRIPIIAGTGANSTREAIELTKAAKDL 95 >4MJM-A nrPDB Length = 385 Score = 28.6 bits (62), Expect = 5.1, Method: Composition-based stats. Identities = 11/32 (34%), Positives = 18/32 (56%) Query: 327 IPIIGVGGVSSGQDALEKIQAGASLVQLYTAL 358 IP+I GG+ D ++ + AGA +V L + Sbjct: 234 IPVIADGGIKYSGDMVKALAAGAHVVMLGSMF 265 >4WY0-A nrPDB Length = 305 Score = 28.6 bits (62), Expect = 5.6, Method: Composition-based stats. Identities = 17/63 (26%), Positives = 27/63 (42%), Gaps = 5/63 (7%) Query: 313 TQTIREMYALTQGRIPI--IGVGGVSSGQDALEKIQAGASLVQLYTA-LIFLGPPVVVRV 369 + +RE+ L GR+P+ GGV++ DA + GA V + + P R Sbjct: 203 VEVLREIKRL--GRLPVVNFAAGGVTTPADAALMMHLGADGVFVGSGIFKSENPEKYARA 260 Query: 370 KRE 372 E Sbjct: 261 IVE 263 >1HG3-A nrPDB Length = 225 Score = 28.2 bits (61), Expect = 5.9, Method: Composition-based stats. Identities = 18/108 (16%), Positives = 37/108 (34%), Gaps = 8/108 (7%) Query: 262 QDKEDIASVARELGIDGLIVTNT-------TVSRPVGLQGALRSETG-GLSGKPLRDLST 313 D E A E+G+ ++ +N P + G G+ + Sbjct: 104 ADLEAAIRRAEEVGLMTMVCSNNPAVSAAVAALNPDYVAVEPPELIGTGIPVSKAKPEVI 163 Query: 314 QTIREMYALTQGRIPIIGVGGVSSGQDALEKIQAGASLVQLYTALIFL 361 E+ + ++ G+S+G+D + I+ G V L + + Sbjct: 164 TNTVELVKKVNPEVKVLCGAGISTGEDVKKAIELGTVGVLLASGVTKA 211 >4BI9-A nrPDB Length = 454 Score = 28.2 bits (61), Expect = 6.0, Method: Composition-based stats. Identities = 29/144 (20%), Positives = 45/144 (31%), Gaps = 11/144 (7%) Query: 220 LRSLQGKTELRHLLSKVLQERDALKGTRKPAVLVKIAPDLTAQDKEDIASVARELGIDGL 279 LR + + V G P + K PD ++ + + + E I+G Sbjct: 18 LRRTSSTFSAKRVFV-VGGHITTFVGKGSPLFIDKKHPDFGKKENKTLEELLAE-SINGA 75 Query: 280 IVTN-------TTVSRPV--GLQGALRSETGGLSGKPLRDLSTQTIREMYALTQGRIPII 330 + V + V G L S G L + LS R+ Sbjct: 76 LQNTGLHDGRAALVDKLVVGNFLGELFSSQGHLGPAAVGSLSGSNSSAFLNKPAVRVEGA 135 Query: 331 GVGGVSSGQDALEKIQAGASLVQL 354 G + Q A E + AG S + L Sbjct: 136 CASGGLAVQSAWEALLAGTSQIAL 159 >1VHN-A nrPDB Length = 318 Score = 28.2 bits (61), Expect = 6.1, Method: Composition-based stats. Identities = 34/159 (21%), Positives = 53/159 (33%), Gaps = 16/159 (10%) Query: 236 VLQERDALKGTRKPAVLVKIAPDLTAQDK---EDIASVARELGIDGLIVTNTTVSRPVGL 292 V+Q + +VL K P + D ED E G DGL+V + RP Sbjct: 164 VVQSFTGRAEWKALSVLEKRIPTFVSGDIFTPEDAKRALEESGCDGLLVARGAIGRPWIF 223 Query: 293 QGALRSETGGLSGKPLRDLSTQTIREMYALTQGRIPIIGVGGVSSGQDALEKIQAGASLV 352 + SGK + +R + +I G + K AG Sbjct: 224 KQIKDFLR---SGKYSEPSREEILRTFERHLE---LLIKTKGERKAVVEMRKFLAG---- 273 Query: 353 QLYTALIFLGPPVVVRVKR-ELEALLKERGFTTVTDAIG 390 YT + +V + E +LKE + + + G Sbjct: 274 --YTKDLKGARRFREKVMKIEEVQILKEMFYNFIKEVEG 310 >4QCC-A nrPDB Length = 291 Score = 28.2 bits (61), Expect = 6.2, Method: Composition-based stats. Identities = 19/123 (15%), Positives = 41/123 (33%), Gaps = 9/123 (7%) Query: 252 LVKIAPDLTAQDKEDIASVARELGIDGLIVTNTTVSRPVGLQGALRSETGGLSGKPLRDL 311 + L + E + D ++ TV +P + R + + Sbjct: 33 FDAVEIPLNSPQWEQSIPAIVDAYGDKALIGAGTVLKPEQVDALARMG--------CQLI 84 Query: 312 STQTIREMYALTQGRIPIIGVGGVSSGQDALEKIQAGASLVQLYTALIFLGPPVVVRVKR 371 T I + G ++ +A ++AGA ++++ + F GP + +K Sbjct: 85 VTPNIHSEVIRRAVGYGMTVCPGCATATEAFTALEAGAQALKIFPSSAF-GPQYIKALKA 143 Query: 372 ELE 374 L Sbjct: 144 VLP 146 >1VRD-A nrPDB Length = 494 Score = 28.2 bits (61), Expect = 6.2, Method: Composition-based stats. Identities = 13/57 (22%), Positives = 23/57 (40%), Gaps = 4/57 (7%) Query: 302 GLSGKPLRDLSTQTIREMYALTQGRIPIIGVGGVSSGQDALEKIQAGASLVQLYTAL 358 G+ L + E+ +PII GG+ D ++ + AGA V + + Sbjct: 320 GVGVPQL--TAVMECSEVARKYD--VPIIADGGIRYSGDIVKALAAGAESVMVGSIF 372 >2V81-A nrPDB Length = 212 Score = 28.2 bits (61), Expect = 6.9, Method: Composition-based stats. Identities = 19/123 (15%), Positives = 41/123 (33%), Gaps = 9/123 (7%) Query: 252 LVKIAPDLTAQDKEDIASVARELGIDGLIVTNTTVSRPVGLQGALRSETGGLSGKPLRDL 311 + L + E + D ++ TV +P + R + + Sbjct: 33 FDAVEIPLNSPQWEQSIPAIVDAYGDKALIGAGTVLKPEQVDALARMG--------CQLI 84 Query: 312 STQTIREMYALTQGRIPIIGVGGVSSGQDALEKIQAGASLVQLYTALIFLGPPVVVRVKR 371 T I + G ++ +A ++AGA ++++ + F GP + +K Sbjct: 85 VTPNIHSEVIRRAVGYGMTVCPGCATATEAFTALEAGAQALKIFPSSAF-GPQYIKALKA 143 Query: 372 ELE 374 L Sbjct: 144 VLP 146 >5LNS-A nrPDB Length = 316 Score = 28.2 bits (61), Expect = 7.0, Method: Composition-based stats. Identities = 13/42 (30%), Positives = 21/42 (50%), Gaps = 2/42 (4%) Query: 325 GRIPI--IGVGGVSSGQDALEKIQAGASLVQLYTALIFLGPP 364 GR+P+ GGV++ DA +Q G V + + + G P Sbjct: 219 GRLPVVQFAAGGVATPADAALMMQLGCDGVFVGSGIFKSGDP 260 >1RPX-A nrPDB Length = 230 Score = 27.8 bits (60), Expect = 7.9, Method: Composition-based stats. Identities = 17/71 (23%), Positives = 32/71 (45%), Gaps = 3/71 (4%) Query: 302 GLSGKPLRDLSTQTIREMYALTQGR--IPIIGVGGVSSGQDALEKIQAGASLVQLYTALI 359 G G+ + + I ++ + R P I V G ++A + I+AGA+ + +A + Sbjct: 152 GFGGQSFIESQVKKISDLRKICAERGLNPWIEVDGGVGPKNAYKVIEAGANALVAGSA-V 210 Query: 360 FLGPPVVVRVK 370 F P +K Sbjct: 211 FGAPDYAEAIK 221 >4PXO-A nrPDB Length = 238 Score = 27.8 bits (60), Expect = 9.2, Method: Composition-based stats. Identities = 15/83 (18%), Positives = 25/83 (30%), Gaps = 12/83 (14%) Query: 17 LGGGGLLFTSYLTATGDDHFYAEYLMPGLQRL-----------LDPESAHRL-AVRVTSL 64 LG L F S + G+ A + + L LD H+ + + Sbjct: 13 LGTENLYFQSMVKMYGNWRSAAAFRVRIALNLKGIAYEEVFLDLDAGDQHKPDFLAINPQ 72 Query: 65 GLLPRATFQDSDMLEVKVLGHKF 87 G +P D L + + Sbjct: 73 GAVPALFDGDGPPLTQSLAILDY 95 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.311 0.128 0.321 Lambda K H 0.267 0.0391 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 13,386,924 Number of Sequences: 36641 Number of extensions: 504834 Number of successful extensions: 2595 Number of sequences better than 10.0: 111 Number of HSP's better than 10.0 without gapping: 95 Number of HSP's successfully gapped in prelim test: 81 Number of HSP's that attempted gapping in prelim test: 2365 Number of HSP's gapped (non-prelim): 206 length of query: 395 length of database: 10,336,785 effective HSP length: 99 effective length of query: 296 effective length of database: 6,709,326 effective search space: 1985960496 effective search space used: 1985960496 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.4 bits) S2: 60 (27.8 bits)