BLASTP 2.2.23 [Feb-03-2010]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.


Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.


Reference for composition-based statistics starting in round 2:
Schaffer, Alejandro A., L. Aravind, Thomas L. Madden,
Sergei Shavirin, John L. Spouge, Yuri I. Wolf,  
Eugene V. Koonin, and Stephen F. Altschul (2001), 
"Improving the accuracy of PSI-BLAST protein database searches with 
composition-based statistics and other refinements",  Nucleic Acids Res. 29:2994-3005.

Query= Q63342
         (857 letters)

Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 
           36,641 sequences; 10,336,785 total letters

Searching..................................................done


Results from round 1


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

4P9S-A nrPDB                                                         1717   0.0  
5L46-A nrPDB                                                         1603   0.0  
1PJ5-A nrPDB                                                          351   9e-97
1YX2-A nrPDB                                                          164   2e-40
1WOR-A nrPDB                                                          150   3e-36
1V5V-A nrPDB                                                          125   1e-28
1VRQ-A nrPDB                                                          117   2e-26
2GAG-A nrPDB                                                          113   3e-25
3A8J-A nrPDB                                                           94   2e-19
1WSR-A nrPDB                                                           89   1e-17
3GIR-A nrPDB                                                           88   2e-17
2GAG-B nrPDB                                                           77   3e-14
3TFJ-A nrPDB                                                           71   2e-12
1NG3-A nrPDB                                                           68   2e-11
3SM8-A nrPDB                                                           66   5e-11
4YSH-A nrPDB                                                           64   3e-10
3AD9-B nrPDB                                                           55   2e-07
3BHF-A nrPDB                                                           45   1e-04
1ZOV-A nrPDB                                                           43   5e-04
2UZZ-A nrPDB                                                           38   0.022
2GAH-C nrPDB                                                           37   0.041
1KNR-A nrPDB                                                           35   0.16 
5KXJ-A nrPDB                                                           34   0.35 
4IV9-A nrPDB                                                           33   0.42 
4C5O-A nrPDB                                                           33   0.44 
5MOG-A nrPDB                                                           33   0.46 
6QZO-A nrPDB                                                           32   0.80 
3L1R-A nrPDB                                                           32   0.85 
3S2F-A nrPDB                                                           32   0.97 
4UIR-A nrPDB                                                           32   1.1  
2JB2-A nrPDB                                                           32   1.7  
3KVE-A nrPDB                                                           31   1.9  
1F8S-A nrPDB                                                           31   2.1  
3RHA-A nrPDB                                                           31   2.4  
4Y4M-A nrPDB                                                           31   2.7  
1VRQ-C nrPDB                                                           31   2.9  
4IVM-B nrPDB                                                           30   3.1  
4K28-A nrPDB                                                           30   3.2  
3ATQ-A nrPDB                                                           30   3.7  
2IVE-A nrPDB                                                           30   4.4  
3RO8-A nrPDB                                                           30   5.1  
1RP0-A nrPDB                                                           30   5.3  
5JMD-A nrPDB                                                           30   5.7  
5Z9A-A nrPDB                                                           30   5.9  
3R9U-A nrPDB                                                           29   7.2  
1REO-A nrPDB                                                           29   7.2  
4N9X-A nrPDB                                                           29   8.8  
6BRD-A nrPDB                                                           29   9.6  

>4P9S-A nrPDB
          Length = 848

 Score = 1717 bits (4447), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 830/836 (99%), Positives = 833/836 (99%)

Query: 22  SSAGLREGQESPPSPPEWKDRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGS 81
           SSAGLREGQESPPSPPEWKDRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGS
Sbjct: 3   SSAGLREGQESPPSPPEWKDRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGS 62

Query: 82  TWHAAGLTTYFHPGINLKKIHYDSIKLYERLEEETGQVVGFHQPGSIRLATTPERVDEFK 141
           TWHAAGLTTYFHPGINLKKIHYDSIKLYERLEEETGQVVGFHQPGSIRLATTPERVDEFK
Sbjct: 63  TWHAAGLTTYFHPGINLKKIHYDSIKLYERLEEETGQVVGFHQPGSIRLATTPERVDEFK 122

Query: 142 YQMTRTNWHATEQYIIEPEKIHELFPLLNMDKILAGLYNPGDGHIDPYSLTMALATGARK 201
           YQMTRTNWHATEQYIIEPEKIHELFPLLNMDKILAGLYNPGDGHIDPYSLTMALATGARK
Sbjct: 123 YQMTRTNWHATEQYIIEPEKIHELFPLLNMDKILAGLYNPGDGHIDPYSLTMALATGARK 182

Query: 202 YGVLLKYPAPVTSLKPRPDGTWDVETPQGSVRANRIVNAAGFWAREVGKMIGLDHPLIPV 261
           YG LLKYPAPVTSLKPRPDGTWDVETPQGSVRANRIVNAAGFWAREVGKMIGLDHPLIPV
Sbjct: 183 YGALLKYPAPVTSLKPRPDGTWDVETPQGSVRANRIVNAAGFWAREVGKMIGLDHPLIPV 242

Query: 262 QHQYVVTSTIPEVKALKRELPVLRDLEGSYYLRQERDGLLFGPYESQEKMKLQASWVAHG 321
           QHQYV+TSTIPEVKALKRELPVLRDLEGSYYLRQERDGLLFGPYESQEKMKLQASWVAHG
Sbjct: 243 QHQYVITSTIPEVKALKRELPVLRDLEGSYYLRQERDGLLFGPYESQEKMKLQASWVAHG 302

Query: 322 VPPGFGKELFESDLDRITEHVEAAMEMVPVLKKADIINIVNGPITYSPDILPMVGPHQGV 381
           VPPGFGKELFESDLDRITEHVEAAMEMVPVLKKADIINIVNGPITYSPDILPMVGPHQGV
Sbjct: 303 VPPGFGKELFESDLDRITEHVEAAMEMVPVLKKADIINIVNGPITYSPDILPMVGPHQGV 362

Query: 382 RNYWVAIGFGYGIIHAGGVGKYLSDWILHGEPPFDLIELDPNRYGKWTTTQYTEAKARES 441
           RNYWVAIGFGYGIIHAGGVG YLSDWILHGEPPFDLIELDPNRYGKWTTTQYTEAKARES
Sbjct: 363 RNYWVAIGFGYGIIHAGGVGTYLSDWILHGEPPFDLIELDPNRYGKWTTTQYTEAKARES 422

Query: 442 YGFNNIVGYPKEERFAGRPTQRVSGLYKILESKCSMGFHAGWEQPHWFYKPGQDTQYRPS 501
           YGFNNIVGYPKEERFAGRPTQRVSGLYKILESKCSMGFHAGWEQPHWFYKPGQDTQYRPS
Sbjct: 423 YGFNNIVGYPKEERFAGRPTQRVSGLYKILESKCSMGFHAGWEQPHWFYKPGQDTQYRPS 482

Query: 502 FRRTNWFRPVGSEYKQVMQRVGVIDLSPFGKFNIKGQDSTQLLDHLCANVIPKVGFTNIS 561
           FRRTNWF PVGSEYKQVMQRVGVIDLSPFGKFNIKGQDSTQLLDHLCANVIPKVGFTNIS
Sbjct: 483 FRRTNWFEPVGSEYKQVMQRVGVIDLSPFGKFNIKGQDSTQLLDHLCANVIPKVGFTNIS 542

Query: 562 HMLTPRGRVYAELTVSHQSPGEFLLITGSGSELHDLRWIEEAAVRGGYDVEIRNITDELG 621
           HMLTPRGRVYAELTVSHQSPGEFLLITGSGSELHDLRWIEEAAVRGGYDVEIRNITDELG
Sbjct: 543 HMLTPRGRVYAELTVSHQSPGEFLLITGSGSELHDLRWIEEAAVRGGYDVEIRNITDELG 602

Query: 622 VLGVAGPYARRVLQKLTSEDLSDDVFKFLQTKSLKISDIPVTAIRISYTGELGWELYHRR 681
           VLGVAGPYARRVLQKLTSEDLSDDVFKFLQTKSLKISDIPVTAIRISYTGELGWELYHRR
Sbjct: 603 VLGVAGPYARRVLQKLTSEDLSDDVFKFLQTKSLKISDIPVTAIRISYTGELGWELYHRR 662

Query: 682 EDSAALYERIMNAGQEEGIDNFGTYALNALRLEKAFRAWGSEMNCDTNPLEAGLDYFIKL 741
           EDSAALYERIMNAGQEEGIDNFGTYALNALRLEKAFRAWGSEMNCDTNPLEAGLDYFIKL
Sbjct: 663 EDSAALYERIMNAGQEEGIDNFGTYALNALRLEKAFRAWGSEMNCDTNPLEAGLDYFIKL 722

Query: 742 NKPADFTGKQALKQIKAKGLKRRLVCLTLATDDVDPEGNESVWYKGKVIGNTTSGSYSYS 801
           NKPA+FTGKQALKQIKAKGLKRRLVCLTLATD+VDPEGNESVWYKGKVIGNTTSGSYSYS
Sbjct: 723 NKPANFTGKQALKQIKAKGLKRRLVCLTLATDNVDPEGNESVWYKGKVIGNTTSGSYSYS 782

Query: 802 IQKSLAFAYVPVELSEVGQQVEVELLGKNYPATIIQEPLVLTEPTRTRLQKDGRKS 857
           IQKSLAFAYVPVELSEVGQQVEVELLGKNYPATIIQEPLVLTEPTRTRLQKDGRKS
Sbjct: 783 IQKSLAFAYVPVELSEVGQQVEVELLGKNYPATIIQEPLVLTEPTRTRLQKDGRKS 838


>5L46-A nrPDB
          Length = 841

 Score = 1603 bits (4150), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 769/832 (92%), Positives = 798/832 (95%), Gaps = 2/832 (0%)

Query: 27  REGQESPPSPPE--WKDRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWH 84
           REG+E PP   E  WKDRAETVIIGGGCVGVSLAYHLAKAGM+DVVLLEKSELTAGSTWH
Sbjct: 5   REGEEKPPLSAETQWKDRAETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGSTWH 64

Query: 85  AAGLTTYFHPGINLKKIHYDSIKLYERLEEETGQVVGFHQPGSIRLATTPERVDEFKYQM 144
           AAGLTTYFHPGINLKKIHYDSIKLYE+LEEETGQVVGFHQPGSIRLATTP RVDEFKYQM
Sbjct: 65  AAGLTTYFHPGINLKKIHYDSIKLYEKLEEETGQVVGFHQPGSIRLATTPVRVDEFKYQM 124

Query: 145 TRTNWHATEQYIIEPEKIHELFPLLNMDKILAGLYNPGDGHIDPYSLTMALATGARKYGV 204
           TRT WHATEQY+IEPEKI E+FPLLNM+K+LAGLYNPGDGHIDPYSLTMALA GARK G 
Sbjct: 125 TRTGWHATEQYLIEPEKIQEMFPLLNMNKVLAGLYNPGDGHIDPYSLTMALAAGARKCGA 184

Query: 205 LLKYPAPVTSLKPRPDGTWDVETPQGSVRANRIVNAAGFWAREVGKMIGLDHPLIPVQHQ 264
           LLKYPAPVTSLK R DGTWDVETPQGS+RANRIVNAAGFWAREVGKMIGL+HPLIPVQHQ
Sbjct: 185 LLKYPAPVTSLKARSDGTWDVETPQGSMRANRIVNAAGFWAREVGKMIGLEHPLIPVQHQ 244

Query: 265 YVVTSTIPEVKALKRELPVLRDLEGSYYLRQERDGLLFGPYESQEKMKLQASWVAHGVPP 324
           YVVTSTIPEVKALKRELPVLRDLEGSYYLRQERDGLLFGPYESQEKMK+Q SWV +GVPP
Sbjct: 245 YVVTSTIPEVKALKRELPVLRDLEGSYYLRQERDGLLFGPYESQEKMKVQDSWVTNGVPP 304

Query: 325 GFGKELFESDLDRITEHVEAAMEMVPVLKKADIINIVNGPITYSPDILPMVGPHQGVRNY 384
           GFGKELFESDLDRI EH++AAMEMVPVLKKADIIN+VNGPITYSPDILPMVGPHQGVRNY
Sbjct: 305 GFGKELFESDLDRIMEHIKAAMEMVPVLKKADIINVVNGPITYSPDILPMVGPHQGVRNY 364

Query: 385 WVAIGFGYGIIHAGGVGKYLSDWILHGEPPFDLIELDPNRYGKWTTTQYTEAKARESYGF 444
           WVAIGFGYGIIHAGGVGKYLSDWILHGEPPFDLIELDPNRYGKWTTTQYTEAKARESYGF
Sbjct: 365 WVAIGFGYGIIHAGGVGKYLSDWILHGEPPFDLIELDPNRYGKWTTTQYTEAKARESYGF 424

Query: 445 NNIVGYPKEERFAGRPTQRVSGLYKILESKCSMGFHAGWEQPHWFYKPGQDTQYRPSFRR 504
           NNIVGYPKEERFAGRPTQRVSGLY+ LESKCSMGFHAGWEQPHWFYKPGQDTQYRPSFRR
Sbjct: 425 NNIVGYPKEERFAGRPTQRVSGLYQRLESKCSMGFHAGWEQPHWFYKPGQDTQYRPSFRR 484

Query: 505 TNWFRPVGSEYKQVMQRVGVIDLSPFGKFNIKGQDSTQLLDHLCANVIPKVGFTNISHML 564
           TNWF PVGSEYKQVMQRV V DLSPFGKFNIKGQDS +LLDHL ANVIPKVGFTNISHML
Sbjct: 485 TNWFEPVGSEYKQVMQRVAVTDLSPFGKFNIKGQDSIRLLDHLFANVIPKVGFTNISHML 544

Query: 565 TPRGRVYAELTVSHQSPGEFLLITGSGSELHDLRWIEEAAVRGGYDVEIRNITDELGVLG 624
           TP+GRVYAELTVSHQSPGEFLLITGSGSELHDLRWIEE AV+GGYDVEI+NITDELGVLG
Sbjct: 545 TPKGRVYAELTVSHQSPGEFLLITGSGSELHDLRWIEEEAVKGGYDVEIKNITDELGVLG 604

Query: 625 VAGPYARRVLQKLTSEDLSDDVFKFLQTKSLKISDIPVTAIRISYTGELGWELYHRREDS 684
           VAGP AR+VLQKLTSEDLSDDVFKFLQTKSLK+S+IPVTAIRISYTGELGWELYHRREDS
Sbjct: 605 VAGPQARKVLQKLTSEDLSDDVFKFLQTKSLKVSNIPVTAIRISYTGELGWELYHRREDS 664

Query: 685 AALYERIMNAGQEEGIDNFGTYALNALRLEKAFRAWGSEMNCDTNPLEAGLDYFIKLNKP 744
            ALY+ IMNAGQEEGIDNFGTYA+NALRLEKAFRAWG EMNCDTNPLEAGL+YF+KLNKP
Sbjct: 665 VALYDAIMNAGQEEGIDNFGTYAMNALRLEKAFRAWGLEMNCDTNPLEAGLEYFVKLNKP 724

Query: 745 ADFTGKQALKQIKAKGLKRRLVCLTLATDDVDPEGNESVWYKGKVIGNTTSGSYSYSIQK 804
           ADF GKQALKQIKAKGLKRRLVCLTLATDDVDPEGNES+WY GKV+GNTTSGSYSYSIQK
Sbjct: 725 ADFIGKQALKQIKAKGLKRRLVCLTLATDDVDPEGNESIWYNGKVVGNTTSGSYSYSIQK 784

Query: 805 SLAFAYVPVELSEVGQQVEVELLGKNYPATIIQEPLVLTEPTRTRLQKDGRK 856
           SLAFAYVPV+LSEVGQQVEVELLGKNYPA IIQEPLVLTEPTR RLQK G K
Sbjct: 785 SLAFAYVPVQLSEVGQQVEVELLGKNYPAVIIQEPLVLTEPTRNRLQKKGGK 836


>1PJ5-A nrPDB
          Length = 830

 Score =  351 bits (900), Expect = 9e-97,   Method: Compositional matrix adjust.
 Identities = 247/839 (29%), Positives = 414/839 (49%), Gaps = 50/839 (5%)

Query: 46  VIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELT--AGSTWHAAGLTTYFHPGINLKKIHY 103
           VIIG G VG +LA  L   G  ++ +L++  L    GST HA GL    +P   +     
Sbjct: 8   VIIGAGIVGTNLADELVTRGWNNITVLDQGPLNMPGGSTSHAPGLVFQTNPSKTMASFAK 67

Query: 104 DSIKLYERLEEETGQVVGFHQPGSIRLATTPERVDEFKYQMTRTNWHATEQYIIEPEKIH 163
            +++    L E+   V  F+Q G + +ATT  R+ + K ++        E  ++ P +  
Sbjct: 68  YTVEKLLSLTED--GVSCFNQVGGLEVATTETRLADLKRKLGYAAAWGIEGRLLSPAECQ 125

Query: 164 ELFPLLNMDKILAGLYNPGDGHIDPYSLTMALATGARKYGVLLKYPAPVTSLKPRPDGTW 223
           EL+PLL+ + IL GL+ P DG          L       GV  +    VT ++       
Sbjct: 126 ELYPLLDGENILGGLHVPSDGLASAARAVQLLIKRTESAGVTYRGSTTVTGIEQSGGRVT 185

Query: 224 DVETPQGSVRANRIVNAAGFWAREVGKMIGLDHPLIPVQHQYVVTSTIPEVKALKRE--- 280
            V+T  G + A+ +V+ AGFW  ++G MIG+  PL+P+ HQYV T+ +P  +    +   
Sbjct: 186 GVQTADGVIPADIVVSCAGFWGAKIGAMIGMAVPLLPLAHQYVKTTPVPAQQGRNDQPNG 245

Query: 281 --LPVLRDLEGSYYLRQERDGLLFGPYESQEKMKLQASWVAHGVPPGFGKELFESDLDRI 338
             LP+LR  +   Y R+  D    G Y +   M +    +    P    +    S LD  
Sbjct: 246 ARLPILRHQDQDLYYREHGDRYGIGSY-AHRPMPVDVDTLGAYAPETVSEHHMPSRLDFT 304

Query: 339 TEHV----EAAMEMVPVLKKADIINIVNGPITYSPDILPMVGPHQGVRNYWVAIGFGYGI 394
            E      EA  +++P L  ++I +  NG  +++PD  P++G  + +  ++VA      +
Sbjct: 305 LEDFLPAWEATKQLLPALADSEIEDGFNGIFSFTPDGGPLLGESKELDGFYVAEAVW--V 362

Query: 395 IHAGGVGKYLSDWILHGEPPFDLIELDPNRYGKWTTT-QYTEAKARESYGFNNIVGYPKE 453
            H+ GV K +++ +  G    DL E D  R+     T +Y    +++++     V +P +
Sbjct: 363 THSAGVAKAMAELLTTGRSETDLGECDITRFEDVQLTPEYVSETSQQNFVEIYDVLHPLQ 422

Query: 454 ERFAGRPTQRVSGLYKILESKCSMGFHAG-WEQPHWFYKPGQDTQYRPSFRRTNWFRPV- 511
            R + R   RVS  +   +   +    AG WE+P+WF       +  P+     W  P  
Sbjct: 423 PRLSPR-NLRVSPFHARHKELGAFFLEAGGWERPYWFEANAALLKEMPA----EWLPPAR 477

Query: 512 ------------GSEYKQVMQRVGVIDLSPFGKFNIKGQDSTQLLDHLC-ANVIPKVGFT 558
                        +E  +    V + D++P  +  + G  + +LL  L  A++  K G  
Sbjct: 478 DAWSGMFSSPIAAAEAWKTRTAVAMYDMTPLKRLEVSGPGALKLLQELTTADLAKKPGAV 537

Query: 559 NISHMLTPRGRVYAELTVSHQSPGEFLLITGSGSELHDLRWIEEAA---VRGGYD---VE 612
             + +L   G V +++TV+  S   F L  G+   + D  + E AA    + G     V+
Sbjct: 538 TYTLLLDHAGGVRSDITVARLSEDTFQL--GANGNI-DTAYFERAARHQTQSGSATDWVQ 594

Query: 613 IRNITDELGVLGVAGPYARRVLQKLTSEDLSDDVFKFLQTKSLKISDIPVTAIRISYTGE 672
           +R+ T     +G+ GP AR ++ K++ +D ++D  K+ + K++ I  IPVTA+R+SY GE
Sbjct: 595 VRDTTGGTCCIGLWGPLARDLVSKVSDDDFTNDGLKYFRAKNVVIGGIPVTAMRLSYVGE 654

Query: 673 LGWELYHRREDSAALYERIMNAGQEEGIDNFGTYALNALRLEKAFRAWGSEMNCDTNPLE 732
           LGWELY   ++   L++ +  AGQ  G+   G  A ++LRLEK +R+WG++M  + +P E
Sbjct: 655 LGWELYTSADNGQRLWDALWQAGQPFGVIAAGRAAFSSLRLEKGYRSWGTDMTTEHDPFE 714

Query: 733 AGLDYFIKLNKPADFTGKQALKQIKAKGLKRRLVCLTLATDDVDPEGNESVWYKGKVIGN 792
           AGL + +K+ K + F GK AL+    +   RRL CLT+        G E V+YK + +G 
Sbjct: 715 AGLGFAVKMAKES-FIGKGALEGRTEEASARRLRCLTIDDGRSIVLGKEPVFYKEQAVGY 773

Query: 793 TTSGSYSYSIQKSLAFAYVPVELSEVGQQVEVELLGKNYPATIIQEPLVLTEPTRTRLQ 851
            TS +Y Y++ K +A++Y+P  +S VG  V++E  G+   AT+ ++PL   +P  TRL+
Sbjct: 774 VTSAAYGYTVAKPIAYSYLPGTVS-VGDSVDIEYFGRRITATVTEDPLY--DPKMTRLR 829


>1YX2-A nrPDB
          Length = 365

 Score =  164 bits (414), Expect = 2e-40,   Method: Compositional matrix adjust.
 Identities = 102/322 (31%), Positives = 165/322 (51%), Gaps = 9/322 (2%)

Query: 508 FRPVGSEYKQVMQRVGVIDLSPFGKFNIKGQDSTQLLDHLCANVIPKV--GFTNISHMLT 565
           F  +  E++ V    G+ D+S  G+  + G DS   L  L  N +  +  G    + M  
Sbjct: 33  FSSIKKEHEAVRTAAGLFDVSHMGEVEVSGNDSLSFLQRLMTNDVSALTPGRAQYTAMCY 92

Query: 566 PRGRVYAELTVSHQSPGEFLLITGSGSELHDLRWIEEAAVRGGYDVEIRNITDELGVLGV 625
           P G    +L +  +    +LL+  + +   DL W++E A     DV+I N +D++ +L V
Sbjct: 93  PDGGTVDDLLIYQKGENRYLLVINASNIDKDLAWMKEHAAG---DVQIDNQSDQIALLAV 149

Query: 626 AGPYARRVLQKLTSEDLSD-DVFKFLQTKSLKISDIPVTAIRISYTGELGWELYHRREDS 684
            GP A  +L+ LT  D+S    F F+      IS       R  YTGE G+E+Y R +D+
Sbjct: 150 QGPKAEAILKNLTDADVSALKPFAFIDEAD--ISGRKALISRTGYTGEDGYEIYCRSDDA 207

Query: 685 AALYERIMNAGQEEGIDNFGTYALNALRLEKAFRAWGSEMNCDTNPLEAGLDYFIKLNKP 744
             ++++I++AG   G+   G  A + LR E     +G E+  D  P+EAG+ + +K  K 
Sbjct: 208 MHIWKKIIDAGDAYGLIPCGLGARDTLRFEANIPLYGQELTRDITPIEAGIGFAVKHKKE 267

Query: 745 ADFTGKQALKQIKAKGLKRRLVCLTLATDDVDPEGNESVWYKGKVIGNTTSGSYSYSIQK 804
           +DF GK  L + K  G KR+LV L +    +   G E V+  GK +G  T+G+ S ++ K
Sbjct: 268 SDFFGKSVLSEQKENGAKRKLVGLEMIEKGIPRHGYE-VFQNGKSVGKVTTGTQSPTLGK 326

Query: 805 SLAFAYVPVELSEVGQQVEVEL 826
           ++  A +  E SE+G  V+VE+
Sbjct: 327 NVGLALIDSETSEIGTVVDVEI 348


>1WOR-A nrPDB
          Length = 364

 Score =  150 bits (378), Expect = 3e-36,   Method: Compositional matrix adjust.
 Identities = 115/379 (30%), Positives = 191/379 (50%), Gaps = 35/379 (9%)

Query: 469 KILESKCSMGFHAGWEQPHWFYKPGQDTQYRPSFRRTNWFRPVGSEYKQVMQRVGVIDLS 528
           K +E    M   AGWE P ++               T+ F     E   V + VG+ D+S
Sbjct: 9   KHVELGAKMVDFAGWEMPLYY---------------TSIFE----EVMAVRKSVGMFDVS 49

Query: 529 PFGKFNIKGQDSTQLLDHLCANVIPKV--GFTNISHMLTPRGRVYAELTVSHQSPGEFLL 586
             G+F +KG ++   +D L  N    +  G    S M    G +  +L V   SP E L+
Sbjct: 50  HMGEFLVKGPEAVSFIDFLITNDFSSLPDGKAIYSVMCNENGGIIDDLVVYKVSPDEALM 109

Query: 587 ITGSGSELHDLRWIEEAAVRGGYDVEIRNITDELGVLGVAGPYARRVLQKLTSEDLSDDV 646
           +  + +   D  WI+  +    +DVE+ NI+D   ++   GP A+  LQ+L  ED  +++
Sbjct: 110 VVNAANIEKDFNWIKSHS--KNFDVEVSNISDTTALIAFQGPKAQETLQELV-EDGLEEI 166

Query: 647 FKFLQTKSLKISDIPVTAIRISYTGELGWELYHRREDSAALYERIMNAGQEEGIDNFGTY 706
             +   KS+ ++ +     R  YTGE G+EL    +++  +++ +MN  ++      G  
Sbjct: 167 AYYSFRKSI-VAGVETLVSRTGYTGEDGFELMLEAKNAPKVWDALMNLLRKIDGRPAGLG 225

Query: 707 ALNALRLEKAFRAWGSEMNCDTNPLEAGLDYFIKLNKPADFTGKQALKQIKAKGLKRRLV 766
           A +  RLE  +  +G +M+ +TNP E GL + +KLNK  DF GK+AL + K K ++R+LV
Sbjct: 226 ARDVCRLEATYLLYGQDMDENTNPFEVGLSWVVKLNK--DFVGKEALLKAKEK-VERKLV 282

Query: 767 CLTLATDDVDPEGNESVWYKGKVIGNTTSGSYSYSIQKSLAFAYVPVELSEVGQQVEVEL 826
            L L+   +  +G E V   G+ +G  TSG++S ++ KS+A A V   + ++G Q     
Sbjct: 283 ALELSGKRIARKGYE-VLKNGERVGEITSGNFSPTLGKSIALALVSKSV-KIGDQ----- 335

Query: 827 LGKNYPATIIQEPLVLTEP 845
           LG  +P   + E LV+ +P
Sbjct: 336 LGVVFPGGKLVEALVVKKP 354


>1V5V-A nrPDB
          Length = 401

 Score =  125 bits (313), Expect = 1e-28,   Method: Compositional matrix adjust.
 Identities = 103/366 (28%), Positives = 178/366 (48%), Gaps = 40/366 (10%)

Query: 507 WFRPVGSEYKQVMQRVGVIDLSPFGKFNIKGQDSTQLLDHLCANVIPKVGFTNISH--ML 564
           W+  +  E+  V   VG+ D+S  G+   +G+D+ + L ++  N I K    + ++  +L
Sbjct: 32  WYSSIKEEHLAVRNAVGIFDVSHMGEIVFRGKDALKFLQYVTTNDISKPPAISGTYTLVL 91

Query: 565 TPRGRVYAELTVSHQSPGEFLLITGSGSELHDLRW-------IEEAAVRGGYDVEIRNIT 617
             RG +  E  V +    E+L+I  S +      W       IE+       D+EI   T
Sbjct: 92  NERGAIKDETLVFNMGNNEYLMICDSDAFEKLYAWFTYLKRTIEQFT---KLDLEIELKT 148

Query: 618 DELGVLGVAGPYARRVLQKLTSEDLSDDVFKFLQTKSLKISDIPVTAIRISYTGELGWEL 677
            ++ +  V GP AR + + L   D+++    + Q + +++  I +   R  YTGE G+E+
Sbjct: 149 YDIAMFAVQGPKARDLAKDLFGIDINE--MWWFQARWVELDGIKMLLSRSGYTGENGFEV 206

Query: 678 Y------------HRREDSAAL--YERIMNAGQEEGIDNFGTYALNALRLEKAFRAWGSE 723
           Y             R E   AL  +ERI+  G++ GI   G  A + LRLE  +  +G+E
Sbjct: 207 YIEDANPYHPDESKRGEPEKALHVWERILEEGKKYGIKPCGLGARDTLRLEAGYTLYGNE 266

Query: 724 ------MNCDTN---PLEAGLDYFIKLNKPADFTGKQALKQIKAKGLKRRLVCLTLATDD 774
                 ++ D +   PL+A L++ I  +K  DF GK AL + K +G+ R+LV   +    
Sbjct: 267 TKELQLLSTDIDEVTPLQANLEFAIYWDK--DFIGKDALLKQKERGVGRKLVHFKMIDKG 324

Query: 775 VDPEGNESVWYKGKVIGNTTSGSYSYSIQKSLAFAYVPVELSEVGQQVEVELLGKNYPAT 834
           +  EG + V+  G++IG  TSG+ S  +   +  A+V  E ++ G ++EVE+ G+   A 
Sbjct: 325 IPREGYK-VYANGEMIGEVTSGTLSPLLNVGIGIAFVKEEYAKPGIEIEVEIRGQRKKAV 383

Query: 835 IIQEPL 840
            +  P 
Sbjct: 384 TVTPPF 389


>1VRQ-A nrPDB
          Length = 964

 Score =  117 bits (293), Expect = 2e-26,   Method: Compositional matrix adjust.
 Identities = 81/279 (29%), Positives = 136/279 (48%), Gaps = 19/279 (6%)

Query: 483 WEQPHWFYKPGQDTQYRPSFRRTNWFRPVGSEYKQVMQRVGVIDLSPFGKFNIKGQDSTQ 542
           W++P W+Y    ++     +R          E K V   VG++D S  GK  I+G+D+ +
Sbjct: 595 WKRP-WYYPQDGESMDEAVYR----------ECKAVRDSVGMLDASTLGKIEIRGKDAAE 643

Query: 543 LLDHLCAN--VIPKVGFTNISHMLTPRGRVYAELTVSHQSPGEFLLITGSGSELHDLRWI 600
            L+ +  N     KVG      M    G ++ +      +   FL+ T +G     L W+
Sbjct: 644 FLNRMYTNGYTKLKVGMGRYGVMCKADGMIFDDGVTLRLAEDRFLMHTTTGGAADVLDWL 703

Query: 601 EE--AAVRGGYDVEIRNITDELGVLGVAGPYARRVLQKLTSE-DLSDDVFKFLQTKSLKI 657
           EE         DV   ++T++L  + V GP +R V+ KL S  D+S+D FKF+  + + +
Sbjct: 704 EEWLQTEWPELDVTCTSVTEQLATVAVVGPRSRDVIAKLASSLDVSNDAFKFMAFQDVTL 763

Query: 658 -SDIPVTAIRISYTGELGWELYHRREDSAALYERIMNAGQEEGIDNFGTYALNALRLEKA 716
            S I     RIS++GEL +E+         ++E +  AGQE  I  +GT  ++ LR EK 
Sbjct: 764 DSGIEARISRISFSGELAFEIAIPAWHGLQVWEDVYAAGQEFNITPYGTETMHVLRAEKG 823

Query: 717 FRAWGSEMNCDTNPLEAGLDYFIKLNKPADFTGKQALKQ 755
           F   G + +    P +AG+++ +  +K  DF GK++  +
Sbjct: 824 FIIVGQDTDGTVTPQDAGMEWVV--SKLKDFVGKRSFSR 860


>2GAG-A nrPDB
          Length = 965

 Score =  113 bits (283), Expect = 3e-25,   Method: Compositional matrix adjust.
 Identities = 83/293 (28%), Positives = 144/293 (49%), Gaps = 20/293 (6%)

Query: 483 WEQPHWFYKPGQDTQYRPSFRRTNWFRPVGSEYKQVMQRVGVIDLSPFGKFNIKGQDSTQ 542
           W++P W+Y    +T  +  +R          E K V   VG++D +  GK  I+G+D+ +
Sbjct: 596 WKRP-WYYPQAGETMDQAVYR----------ESKAVRDSVGMLDATTLGKIEIRGKDAAE 644

Query: 543 LLDHLCAN--VIPKVGFTNISHMLTPRGRVYAELTVSHQSPGEFLLITGSGSELHDLRWI 600
            L+ +  N     KVG      M    G ++ +      +   FLL T +G     L W+
Sbjct: 645 FLNRIYTNGYTKLKVGMGRYGVMCKADGMIFDDGVTLRLAEDRFLLHTTTGGAADVLDWL 704

Query: 601 EE--AAVRGGYDVEIRNITDELGVLGVAGPYARRVLQKLTSE-DLSDDVFKFLQTKSLKI 657
           EE         DV   ++T++L  + V GP +R V+ KL S  D+S++ FKF+  K + +
Sbjct: 705 EEWLQTEWPDLDVTCTSVTEQLATVAVVGPRSRDVIAKLASTVDVSNEGFKFMAFKDVVL 764

Query: 658 -SDIPVTAIRISYTGELGWELYHRREDSAALYERIMNAGQEEGIDNFGTYALNALRLEKA 716
            S I     RIS++GEL +E+         ++E +  AG+E  I  +GT  ++ LR EK 
Sbjct: 765 DSGIEARISRISFSGELAFEIAVPAWHGLRVWEDVYAAGEEFNITPYGTETMHVLRAEKG 824

Query: 717 FRAWGSEMNCDTNPLEAGLDYFIKLNKPADFTGKQALKQI-KAKGLKRRLVCL 768
           F   G + +    P +AG+++ +  +K  DF G ++  +   A+  +++LV +
Sbjct: 825 FIIVGQDTDGTVTPQDAGMEWVV--SKLKDFIGNRSYSRADNAREDRKQLVSV 875


>3A8J-A nrPDB
          Length = 364

 Score = 94.4 bits (233), Expect = 2e-19,   Method: Compositional matrix adjust.
 Identities = 94/355 (26%), Positives = 160/355 (45%), Gaps = 41/355 (11%)

Query: 507 WFRPV--GS---EYKQVMQRVGVIDLSPFGKFNIKGQDSTQLLDHLCANVIPKV---GFT 558
           W  P+  GS   E+  V    G+ D+S     +++G  + + L +L AN + K+   G  
Sbjct: 24  WMMPLHYGSQIDEHHAVRTDAGMFDVSHMTIVDLRGSRTREFLRYLLANDVAKLTKSGKA 83

Query: 559 NISHMLTPRGRVYAELTVSHQSPGEFLLITGSGSELHDLRWIEEAAVRGGYDVEIRNITD 618
             S ML   G V  +L V + +   F L+  S +   DL WI + A   G ++ +R   D
Sbjct: 84  LYSGMLNASGGVIDDLIVYYFTEDFFRLVVNSATREKDLSWITQHAEPFGIEITVR---D 140

Query: 619 ELGVLGVAGPYARRVLQKLTSEDLSDDVFKFLQTKSLKISDIPVTAIRISYTGELGWELY 678
           +L ++ V GP A+     L ++     V        ++  D+ +      YTGE G+E+ 
Sbjct: 141 DLSMIAVQGPNAQAKAATLFNDAQRQAVEGMKPFFGVQAGDLFIATT--GYTGEAGYEIA 198

Query: 679 HRREDSAALYERIMNAGQEEGIDNFGTYALNALRLEKAFRAWGSEMNCDTNPLEAGLDYF 738
              E +A  +  ++    E G+   G  A + LRLE     +G EM+   +PL A + + 
Sbjct: 199 LPNEKAADFWRALV----EAGVKPCGLGARDTLRLEAGMNLYGQEMDETISPLAANMGWT 254

Query: 739 IKLNKPA--DFTGKQALKQIKAKGLKRRLVCLTLATDDV----------DPEGNESVWYK 786
           I   +PA  DF G++AL+  +  G + +LV L +    V          D +GN+     
Sbjct: 255 IAW-EPADRDFIGREALEVQREHGTE-KLVGLVMTEKGVLRNELPVRFTDAQGNQHE--- 309

Query: 787 GKVIGNTTSGSYSYSIQKSLAFAYVPVELSEVGQQVEVELLGKNYPATIIQEPLV 841
               G  TSG++S ++  S+A A VP     +G+   V++  +  P  + +   V
Sbjct: 310 ----GIITSGTFSPTLGYSIALARVP---EGIGETAIVQIRNREMPVKVTKPVFV 357


>1WSR-A nrPDB
          Length = 375

 Score = 88.6 bits (218), Expect = 1e-17,   Method: Compositional matrix adjust.
 Identities = 98/377 (25%), Positives = 162/377 (42%), Gaps = 44/377 (11%)

Query: 481 AGWEQPHWFYKPGQDTQYRPSFRRTNWFRPVGSEYKQVMQRVGVIDLSPFGKFNIKGQDS 540
           AGW  P          QYR S   ++             Q   + D+S   +  I G D 
Sbjct: 25  AGWSLP---------VQYRDSHTDSHL---------HTRQHCSLFDVSHMLQTKILGSDR 66

Query: 541 TQLLDHLC----ANVIPKVGFTNISHMLTPRGRVYAELTVSHQSPGEFLLITGSGSELHD 596
            +L++ L     A + P  G   +S      G +  +L V++ S G   +++ +G    D
Sbjct: 67  VKLMESLVVGDIAELRPNQG--TLSLFTNEAGGILDDLIVTNTSEGHLYVVSNAGCWEKD 124

Query: 597 LRWIEEAA---VRGGYDVEIRNITDELGVLGVAGPYARRVLQKLTSEDLSDDVFKFLQTK 653
           L  +++        G DV +  + + L  L + GP A +VLQ   ++DL      F+ + 
Sbjct: 125 LALMQDKVRELQNQGRDVGLEVLDNAL--LALQGPTAAQVLQAGVADDLRK--LPFMTSA 180

Query: 654 SLKISDIP-VTAIRISYTGELGWELYHRREDSAALYERIMNAGQEEGIDNFGTYALNALR 712
            +++  +      R  YTGE G E+      +  L   I+   +   +   G  A ++LR
Sbjct: 181 VMEVFGVSGCRVTRCGYTGEDGVEISVPVAGAVHLATAILKNPE---VKLAGLAARDSLR 237

Query: 713 LEKAFRAWGSEMNCDTNPLEAGLDYFIKLNKPA--DFTG-KQALKQIKAKGLKRR--LVC 767
           LE     +G++++  T P+E  L + +   + A  DF G K  + Q+K +  +RR  L+C
Sbjct: 238 LEAGLCLYGNDIDEHTTPVEGSLSWTLGKRRRAAMDFPGAKVIVPQLKGRVQRRRVGLMC 297

Query: 768 LTLATDDVDPEGNESVWYKGKVIGNTTSGSYSYSIQKSLAFAYVPVELSEVGQQVEVELL 827
                    P  N     +G  IG  TSG  S S++K++A  YVP E S  G  + VE+ 
Sbjct: 298 EGAPMRAHSPILN----MEGTKIGTVTSGCPSPSLKKNVAMGYVPCEYSRPGTMLLVEVR 353

Query: 828 GKNYPATIIQEPLVLTE 844
            K   A + + P V T 
Sbjct: 354 RKQQMAVVSKMPFVPTN 370


>3GIR-A nrPDB
          Length = 393

 Score = 87.8 bits (216), Expect = 2e-17,   Method: Compositional matrix adjust.
 Identities = 89/338 (26%), Positives = 148/338 (43%), Gaps = 19/338 (5%)

Query: 510 PVG--SEYKQVMQRVGVIDLSPFGKFNIKGQDSTQLLDHL--CANVIPKVGFTNISHMLT 565
           P+G   E+       G+ D+S      ++G  + + L +       + K+G +  S++L 
Sbjct: 62  PLGVLKEHLHTRAHAGLFDISHMKLIAVEGPKAVEFLSYALPVDAALLKIGQSRYSYLLN 121

Query: 566 PRGRVYAELTVSHQSPGEFLLITGSGSELHDLRWIEEAAVRGGYDVEIRNITDELGVLGV 625
            R  +  +L ++  +   F+L+  +G+   D   +E+ A    +  E + I  E  +L +
Sbjct: 122 ERAGILDDLILTRLAECRFMLVANAGNAQADFAELEKRA----FGFECQVIALERVLLAL 177

Query: 626 AGPYARRVLQKLTSEDLSDDVFKFLQTKSLKISDIPVTAIRISYTGELGWELYHRREDSA 685
            GP A  VL       L  +   F+Q    +  D  +T  R  YTGE G+E+      + 
Sbjct: 178 QGPQAAAVL---ADAGLPGNELLFMQGFEPQ-QDWFIT--RSGYTGEDGFEIALPIGCAR 231

Query: 686 ALYERIMNAGQEEGIDNFGTYALNALRLEKAFRAWGSEMNCDTNPLEAGLDYFIKLN--K 743
           AL E+++   + E +   G  A ++LRLE      G+++  DT P++A L + +  N  +
Sbjct: 232 ALAEKLLGDSRVEWV---GLAARDSLRLEAGLCLHGNDITPDTTPIDAALTWAVPKNVRE 288

Query: 744 PADFTGKQALKQIKAKGLKRRLVCLTLATDDVDPEGNESVWYKGKVIGNTTSGSYSYSIQ 803
            A F G +A  +   KG  R  V L   T      G      +G  IG  TSG +  S  
Sbjct: 289 KAQFYGAKAFLESLQKGPSRCRVGLKPQTRQPIRAGAVLFDNEGNRIGVVTSGGFGPSFD 348

Query: 804 KSLAFAYVPVELSEVGQQVEVELLGKNYPATIIQEPLV 841
             +A  YVPV     G +V  EL GK    ++   P V
Sbjct: 349 GPVAMGYVPVAWKVEGTEVFTELRGKKIALSVHSLPFV 386


>2GAG-B nrPDB
          Length = 405

 Score = 77.0 bits (188), Expect = 3e-14,   Method: Compositional matrix adjust.
 Identities = 91/395 (23%), Positives = 161/395 (40%), Gaps = 38/395 (9%)

Query: 37  PEWKDRAETVIIGGGCVGVSLAYHLAKA-GMRDVVLLEKSELTAGSTWHAAGLTTYFHPG 95
           PE K   + +I+GGG  G++ AY LAK  G+ +V +LEK  L  G+      +    +  
Sbjct: 16  PEPKKSYDAIIVGGGGHGLATAYFLAKNHGITNVAVLEKGWLAGGNMARNTTIIRSNYLW 75

Query: 96  INLKKIHYDSIKLYERLEEETGQVVGFHQPGSIRLATTPERVDEFKYQMTRTNWHATEQY 155
                I+  S+KL+E+L E+      F Q G + LA T   V E   ++     +  +  
Sbjct: 76  DESAGIYEKSLKLWEQLPEDLEYDFLFSQRGVLNLAHTLGDVRESVRRVEANKLNGVDAE 135

Query: 156 IIEPEKIHELFPLLNMDK-----ILAGLYNPGDGHIDPYSLTMALATGARKYGVLLKYPA 210
            ++P ++ E  P++N        ++   + P  G      +  A A  A + GV +    
Sbjct: 136 WLDPSQVKEACPIINTSDDIRYPVMGATWQPRAGIAKHDHVAWAFARKANEMGVDIIQNC 195

Query: 211 PVTSLKPRPDGTWDVETPQGSVRANRIVNAAGFWAREVGKMIGLDHPLIPVQHQYVVTST 270
            VT      +    V+T +G++ A ++  A    +  + +M G + P+     Q +V+  
Sbjct: 196 EVTGFIKDGEKVTGVKTTRGTIHAGKVALAGAGHSSVLAEMAGFELPIQSHPLQALVSEL 255

Query: 271 IPEVKALKRELPVLRDLEGSYYLRQERDGLLFGPYESQEKMKLQASWVAHGVPP--GFGK 328
              V        V+       Y+ Q   G L                +  G+    G+G+
Sbjct: 256 FEPVHPT-----VVMSNHIHVYVSQAHKGELV---------------MGAGIDSYNGYGQ 295

Query: 329 ELFESDLDRITEHVEAAMEMVPVLKKADIINIVNGPITYSPDILPMVGPHQGVRNYWVAI 388
                    I E + AA+E+ P+  +A ++    G +  + D  P++     ++N +V  
Sbjct: 296 ---RGAFHVIQEQMAAAVELFPIFARAHVLRTWGGIVDTTMDASPIISK-TPIQNLYVNC 351

Query: 389 GFGYGIIHAG-GVGKYLSDWILHGEP-----PFDL 417
           G+G G      G G  L+  I + EP     PF L
Sbjct: 352 GWGTGGFKGTPGAGFTLAHTIANDEPHELNKPFSL 386


>3TFJ-A nrPDB
          Length = 369

 Score = 70.9 bits (172), Expect = 2e-12,   Method: Compositional matrix adjust.
 Identities = 69/345 (20%), Positives = 152/345 (44%), Gaps = 27/345 (7%)

Query: 508 FRPVGSEYKQVMQRVGVIDLSPFGKFNIKGQDSTQLLDHLCANVIPK--VGFTNISHMLT 565
           F  +   YK + + V + D++   +  I G+DS +L+  +    + K  +G      ++ 
Sbjct: 41  FGSIEDSYKHLKEHVQIWDVAAERQVEISGKDSAELVQLMTCRDLSKSKIGRCYYCPIID 100

Query: 566 PRGRVYAELTVSHQSPGEFLLITGSGSELHDLRWIEEAAVRGGYDVEIRNITDELGVLGV 625
             G +  +  V      ++ +       +   +      +  G+  +++ +   + ++ +
Sbjct: 101 ENGNLVNDPVVLKLDENKWWISIADSDVIFFAK-----GLASGHKFDVKIVEPVVDIMAI 155

Query: 626 AGPYARRVLQKLTSEDLSD------DVFKFLQTKSLKISDIPVTAIRISYTGELGWELYH 679
            GP +  +++K+  + +++      D F F  TK L          R  ++ + G+E+Y 
Sbjct: 156 QGPKSFALMEKVFGKKITELKFFGFDYFDFEGTKHL--------IARSGWSKQGGYEVYV 207

Query: 680 RREDSA-ALYERIMNAGQEEGIDNFGTYALNAL-RLEKAFRAWGSEMNCDTNPLEAGLDY 737
               S   LY+ +   G+E    N G    N + R+E A  ++G++ + + NP E G D 
Sbjct: 208 ENTQSGQKLYDHLFEVGKEF---NVGPGCPNLIERIESALLSYGNDFDNNDNPFECGFDQ 264

Query: 738 FIKLNKPADFTGKQALKQIKAKGLKRRLVCLTLATDDVDPEGNESVW-YKGKVIGNTTSG 796
           ++ L+   +F GK+ LK+IK KG +++L  + +   ++   G+++++     VIG   S 
Sbjct: 265 YVSLDSDINFLGKEKLKEIKLKGPQKKLRGVKIDIKEISLTGSKNIYDENNNVIGELRSA 324

Query: 797 SYSYSIQKSLAFAYVPVELSEVGQQVEVELLGKNYPATIIQEPLV 841
            YS   QK +  A +     E  Q  ++++        +   P +
Sbjct: 325 CYSPHFQKVIGIAMIKKSHWEASQGFKIQINDNTINGNVCDLPFI 369


>1NG3-A nrPDB
          Length = 390

 Score = 67.8 bits (164), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 89/367 (24%), Positives = 152/367 (41%), Gaps = 50/367 (13%)

Query: 59  YHLAKAGMRDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKIHYD----SIKLYERLEE 114
           Y+LAK   ++  L E   +   +T  AAG+    H     +   +D    S +LY+ L E
Sbjct: 42  YYLAKEN-KNTALFESGTMGGRTTSAAAGMLGA-HAECEERDAFFDFAMHSQRLYKGLGE 99

Query: 115 ETGQVVGF----HQPGSIRLATTPERVDEFKY--QMTRTNWHATEQYIIEPEKIHELFPL 168
           E   + G     H  G  +LA + E V + +    +   +W++ E+ ++E E      P 
Sbjct: 100 ELYALSGVDIRQHNGGMFKLAFSEEDVLQLRQMDDLDSVSWYSKEE-VLEKE------PY 152

Query: 169 LNMDKILAGLYNPGDGHIDPYSLTMALATGARKYGVLLKYPAPVTSLKPRPDGTWDVETP 228
            + D I    +   D H++PY +  A    A+  G  +    PV  ++   +  + ++TP
Sbjct: 153 ASGD-IFGASFIQDDVHVEPYFVCKAYVKAAKMLGAEIFEHTPVLHVERDGEALF-IKTP 210

Query: 229 QGSVRANRIVNAAGFWAREVGKMIGLDHPLIPVQHQY--VVTSTIPEVKALKRELPVLRD 286
            G V AN +V A+G W+    K +GL++  +PV+ +   V    IP  K L  +      
Sbjct: 211 SGDVWANHVVVASGVWSGMFFKQLGLNNAFLPVKGECLSVWNDDIPLTKTLYHD------ 264

Query: 287 LEGSYYLRQERDGLLFGPYESQEKMKLQASWVAHGVPPGFGKELFESDLDRITEHVEAAM 346
                Y+   + G L                V   + PG   E    DL  +   ++ A 
Sbjct: 265 ---HCYIVPRKSGRLV---------------VGATMKPGDWSE--TPDLGGLESVMKKAK 304

Query: 347 EMVPVLKKADIINIVNGPITYSPDILPMVGPH-QGVRNYWVAIGFGYGIIHAGGVGKYLS 405
            M+P ++   +     G    + D  P +G H +  R  + A  F  GI+ A   G  +S
Sbjct: 305 TMLPPIQNMKVDRFWAGLRPGTKDGKPYIGRHPEDSRILFAAGHFRNGILLAPATGALIS 364

Query: 406 DWILHGE 412
           D I++ E
Sbjct: 365 DLIMNKE 371


>3SM8-A nrPDB
          Length = 381

 Score = 66.2 bits (160), Expect = 5e-11,   Method: Compositional matrix adjust.
 Identities = 96/396 (24%), Positives = 160/396 (40%), Gaps = 58/396 (14%)

Query: 43  AETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKIH 102
           A+ ++IG G  G S  Y L+  G R VVL  +++    ST  +A   T  +    ++ + 
Sbjct: 10  ADYLVIGAGIAGASTGYWLSAHG-RVVVLEREAQPGYHSTGRSAAHYTVAYGTPQVRALT 68

Query: 103 YDSIKLYERLEEETGQVVGFHQPGSIRLATTPERV-------DEFKYQMTRTNWHATEQY 155
             S   ++          GF +     L+  PE V       +E + Q         +  
Sbjct: 69  AASRAFFDN------PPAGFCE--HPLLSPRPEMVVDFSDDPEELRRQYESGKALVPQMR 120

Query: 156 IIEPEKIHELFPLLNMDKILAGLYNPGDGHIDPYSLTMALATGARKYG--VLLKYPAPVT 213
           +++ E+   + P+L  DK+    Y+P    ID  +L      G R+    VL  + A   
Sbjct: 121 LLDAEQACSIVPVLRRDKVFGATYDPTGADIDTDALHQGYLRGIRRNQGQVLCNHEALEI 180

Query: 214 SLKPRPDGTWDVETPQGSVRANRIVNAAGFWAREVGKMIGLDHP--LIPVQHQYVVTSTI 271
               R DG W+V    GS RA  +VNAAG W   +  + G+  P  L P +    + +  
Sbjct: 181 R---RVDGAWEVRCDAGSYRAAVLVNAAGAWCDAIAGLAGV-RPLGLQPKRRSAFIFAPP 236

Query: 272 PEVKALKRELPVLRDLEGSYYLRQERDGLLFGPYESQEKMKLQASWVAHGVPPGFGKELF 331
           P +     + P+L  L+ S+YL+ +  G+L G   + + ++      AH V P       
Sbjct: 237 PGIDC--HDWPMLVSLDESFYLKPDA-GMLLGSPANADPVE------AHDVQP------- 280

Query: 332 ESDLDRITEHVEAAMEMVPVLKKADIINIVNGPITYSPDILPMVGPHQGVRNY------- 384
                   E ++ A  M  ++++A  + I     T++  +   V     V  Y       
Sbjct: 281 --------EQLDIATGMY-LIEEATTLTIRRPEHTWA-GLRSFVADGDLVAGYAANAEGF 330

Query: 385 -WVAIGFGYGIIHAGGVGKYLSDWILHGEPPFDLIE 419
            WVA   GYGI  +  +G+  +  I H   P  L E
Sbjct: 331 FWVAAQGGYGIQTSAAMGEASAALIRHQPLPAHLRE 366


>4YSH-A nrPDB
          Length = 376

 Score = 63.9 bits (154), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 83/326 (25%), Positives = 139/326 (42%), Gaps = 40/326 (12%)

Query: 108 LYERLEEETGQVVGFHQPGSIRLATTPERVDEFKYQMTRTNWHATE---QYIIEPEKIHE 164
           L E L E TG  +G  + G I+LATT E  D+     T   W       Q++ + E + E
Sbjct: 76  LAEELRERTGIDIGLVEKGLIKLATTEEEADDLYRHYT--FWRGIGEPVQWLTKGEAL-E 132

Query: 165 LFPLLNMDKILAGLYNPGDGHIDPYSLTMALATGARKYGVLLKYPAPVTSLKPRPDGTWD 224
           + P L  + +   +Y PGDG +    L  ALA  A   G  L     V  ++    G   
Sbjct: 133 MEPRLA-EALAGAMYIPGDGQVSAPDLAAALAYAAASAGACLYEYTEVFDIRSDSSGHV- 190

Query: 225 VETPQGSVRANRIVNAAGFWAREVGKMIGLDHPLIPVQHQYVVTSTIPEVKALKRELPVL 284
           ++T  G+  A  +V A+G WA  +G  +GL   + PV+ + V+         ++  +P+L
Sbjct: 191 LDTTGGTFAAEAVVIASGAWAARLGARVGLSLSVYPVKGECVM---------VRAPVPLL 241

Query: 285 RDL----EGSYYLRQERDGLLFGPYESQEKMKLQASWVAHGVPPGFGKELFESDLDRITE 340
           +       G Y + +  + LL G               A   P  F + +    +  +  
Sbjct: 242 QTTVFAKNGCYIVPKSGNRLLIG---------------ATSTPGTFDRRVSAGGVMNL-- 284

Query: 341 HVEAAMEMVPVLKKADIINIVNGPITYSPDILPMVGPHQGVRNYWVAIG-FGYGIIHAGG 399
            +  A  +VP +++A+ +   +G    + D LP +G H   R  +VA G +  GI+ +  
Sbjct: 285 -LHRAAHLVPDIEQAEWVASWSGIRPQTEDGLPYLGEHPERRGLFVAAGHYRNGILLSPL 343

Query: 400 VGKYLSDWILHGEPPFDLIELDPNRY 425
            G  ++D +   E  FDL      R+
Sbjct: 344 TGLLVADLVERKETAFDLAPFSLTRH 369


>3AD9-B nrPDB
          Length = 404

 Score = 54.7 bits (130), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 85/384 (22%), Positives = 153/384 (39%), Gaps = 52/384 (13%)

Query: 55  VSLAYHLAKA-GMRDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKIHYDSIKLYERLE 113
           ++ AY+LAK  G+ +V +LEK  L  G+    A  TT     I    +  +S  +YE+  
Sbjct: 33  LATAYYLAKNHGITNVAVLEKGWLAGGNM---ARNTTI----IRSNYLWDESAGIYEKSL 85

Query: 114 EETGQVVG-------FHQPGSIRLATTPERVDEFKYQMTRTNWHATEQYIIEPEKIHELF 166
           +   ++         F Q G + LA T   V E   ++    ++  +   + PE++ E+ 
Sbjct: 86  KLWEELPEELEYDFLFSQRGVLNLAHTLGDVRESIRRVEANKFNGVDAEWLTPEQVKEVC 145

Query: 167 PLLNMDK-----ILAGLYNPGDGHIDPYSLTMALATGARKYGVLLKYPAPVTSLKPRPDG 221
           P++N        ++   Y P  G      +  A A  A + GV +     VT      + 
Sbjct: 146 PIINTGDNIRYPVMGATYQPRAGIAKHDHVAWAFARKANEMGVDIIQNCEVTGFLKDGEK 205

Query: 222 TWDVETPQGSVRANRIVNAAGFWAREVGKMIGLDHPLIPVQHQYVVTSTIPEVKALKREL 281
              V+T +G++ A ++  A    +  + ++ G + P+     Q +V+     V       
Sbjct: 206 VTGVKTTRGTILAGKVALAGAGHSSVLAELAGFELPIQSHPLQALVSELFEPVHPT---- 261

Query: 282 PVLRDLEGSYYLRQERDGLLFGPYESQEKMKLQASWVAHGVPP--GFGKELFESDLDRIT 339
            V+       Y+ Q   G L                +  G+    G+G+         I 
Sbjct: 262 -VVMSNHIHVYVSQAHKGELV---------------MGAGIDSYNGYGQ---RGAFHVIE 302

Query: 340 EHVEAAMEMVPVLKKADIINIVNGPITYSPDILPMVGPHQGVRNYWVAIGFGYGIIHAG- 398
           E + AA+E+ P+  +A ++    G +  + D  P++     ++N +V  G+G G      
Sbjct: 303 EQMAAAVELFPIFARAHVLRTWGGIVDTTMDASPIISK-TPIQNLYVNCGWGTGGFKGTP 361

Query: 399 GVGKYLSDWILHGEP-----PFDL 417
           G G  L+  I H EP     PF L
Sbjct: 362 GAGYTLAHTIAHDEPHKLNAPFAL 385


>3BHF-A nrPDB
          Length = 390

 Score = 45.1 bits (105), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 84/393 (21%), Positives = 159/393 (40%), Gaps = 32/393 (8%)

Query: 44  ETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAGLTTYFHP---GINLKK 100
           + +++G G +G++  Y LAK G++  +L++  +    +  H        H    G     
Sbjct: 6   DVIVVGAGSMGMAAGYQLAKQGVK-TLLVDAFDPPHTNGSHHGDTKIIRHAYGEGREYVP 64

Query: 101 IHYDSIKLYERLEEETGQVVGFHQPGSIRLATTPERVDEFKYQ-MTRTNWHATEQYIIEP 159
           +   S +L+  LE+ET   + F + G +     P+    F  + M     H+    ++E 
Sbjct: 65  LALRSQELWYELEKETHHKI-FTKTGVLVFG--PKGESAFVAETMEAAKEHSLTVDLLEG 121

Query: 160 EKIHELFPLLNMDKILAGLYNPGDGHIDPYSLTMALATGARKYGVLLKYPAPVTSLKPRP 219
           ++I++ +P + + +    ++ P  G +   +   A    A   G  +     V      P
Sbjct: 122 DEINKRWPGITVPENYNAIFEPNSGVLFSENCIRAYRELAEARGAKVLTHTRVEDFDISP 181

Query: 220 DGTWDVETPQGSVRANRIVNAAGFWAREVGKMIGLDHPLIPVQHQYVVTSTIPEVKALKR 279
           D +  +ET  GS  A++++ + G W  ++   + LD PL P + Q V      E K    
Sbjct: 182 D-SVKIETANGSYTADKLIVSMGAWNSKLLSKLNLDIPLQPYR-QVVGFFESDESK---- 235

Query: 280 ELPVLRDLEGSYYLRQERDGLLFG-PYESQEKMKLQASWVAHGVPPG-----FGKELFES 333
                 D++   ++ +  +G+ +G P      +KL        + P      FG  ++  
Sbjct: 236 ---YSNDIDFPGFMVEVPNGIYYGFPSFGGCGLKLGYHTFGQKIDPDTINREFG--VYPE 290

Query: 334 DLDRITEHVEAAMEMVP-VLKKADIINIVNGPITYSPDILPMVGPHQGVRNYWVAIGF-G 391
           D   +   +E  M      LK+  +        T + D   ++  H    N  +A GF G
Sbjct: 291 DESNLRAFLEEYMPGANGELKRGAVCM-----YTKTLDEHFIIDLHPEHSNVVIAAGFSG 345

Query: 392 YGIIHAGGVGKYLSDWILHGEPPFDLIELDPNR 424
           +G   + GVG+ LS   L G+   D+     NR
Sbjct: 346 HGFKFSSGVGEVLSQLALTGKTEHDISIFSINR 378


>1ZOV-A nrPDB
          Length = 386

 Score = 43.1 bits (100), Expect = 5e-04,   Method: Compositional matrix adjust.
 Identities = 45/220 (20%), Positives = 95/220 (43%), Gaps = 7/220 (3%)

Query: 44  ETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAG--LTTYFHPGINLKKI 101
           + +++G G +G++  Y+LAK G++ +++          + H     +   +  G      
Sbjct: 5   DVIVVGAGSMGMAAGYYLAKQGVKTLLVDSFDPPHTNGSHHGDTRIIRHAYGEGREYVPF 64

Query: 102 HYDSIKLYERLEEETGQVVGFHQPGSIRLATTPERVDEFKYQ-MTRTNWHATEQYIIEPE 160
              + +L+  LE+ET   + F Q G   L   P+    F  + M   N H+ E  + E +
Sbjct: 65  ALRAQELWYELEKETHHKI-FTQTGV--LVYGPKGGSAFVSETMEAANIHSLEHELFEGK 121

Query: 161 KIHELFPLLNMDKILAGLYNPGDGHIDPYSLTMALATGARKYGVLLKYPAPVTSLKPRPD 220
           ++ + +  + +      ++ P  G +   +   A    A  +G  +    PV   +   D
Sbjct: 122 QLTDRWAGVEVPDNYEAIFEPNSGVLFSENCIQAYRELAEAHGATVLTYTPVEDFEVTED 181

Query: 221 GTWDVETPQGSVRANRIVNAAGFWAREVGKMIGLDHPLIP 260
               ++T +GS  AN++V + G W  ++   + ++ PL P
Sbjct: 182 -LVTIKTAKGSYTANKLVVSMGAWNSKLLSKLDVEIPLQP 220


>2UZZ-A nrPDB
          Length = 372

 Score = 37.7 bits (86), Expect = 0.022,   Method: Compositional matrix adjust.
 Identities = 90/424 (21%), Positives = 152/424 (35%), Gaps = 94/424 (22%)

Query: 42  RAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTA-------GST---WHAAGLTTY 91
           + + +IIG G VG +  Y+  +AG+   VL+  + +         G T    HA G    
Sbjct: 2   KYDLIIIGSGSVGAAAGYYATRAGLN--VLMTDAHMPPHQHGSHHGDTRLIRHAYGEGEK 59

Query: 92  FHPGINLKKIHYDSIKLYERLEEETGQVVGFHQPGSIRLATTPERVDEFKYQMTRTNWHA 151
           + P +   ++      L++ L         F + G I L                   H+
Sbjct: 60  YVPLVLRAQM------LWDELSRHNEDDPIFVRSGVINLGPADS-------TFLANVAHS 106

Query: 152 TEQYIIEPEK-----IHELFPLLNMDKILAGLYNPGDGHIDPYSLTMALATGARKYGVLL 206
            EQ+ +  EK     I   +P + +     GL+    G +            A++ G   
Sbjct: 107 AEQWQLNVEKLDAQGIMARWPEIRVPDNYIGLFETDSGFLRSELAIKTWIQLAKEAGCAQ 166

Query: 207 KYPAPVTSLKPRPDGTWDVETPQGSVRANRIVNAAGFWAREVGKMIGLDHPLIPVQ---- 262
            +  PVT+++   DG   +ET  G  +A + +  AG W +++        P +PVQ    
Sbjct: 167 LFNCPVTAIRHDDDGV-TIETADGEYQAKKAIVCAGTWVKDL-------LPELPVQPVRK 218

Query: 263 --------HQYVVTSTIPEVKALKRELPVLRDLEGSYYLRQERDGLLFGPYESQEKMKLQ 314
                    +Y V +  P   A   ELP   + +  Y    E D L  G +         
Sbjct: 219 VFAWYQADGRYSVKNKFP---AFTGELP---NGDQYYGFPAENDALKIGKHN-------- 264

Query: 315 ASWVAHGVPPGFGKELFESDLDRI--TEHVEAAMEMVPVLKKADIINIVNG--------P 364
                       G ++  S  +R+   E V    E  P L+     N++ G         
Sbjct: 265 ------------GGQVIHSADERVPFAEVVSDGSEAFPFLR-----NVLPGIGCCLYGAA 307

Query: 365 ITY--SPDILPMVGPHQGVRNYWVAIGF-GYGIIHAGGVGKYLSDWILHGEPPFDLIELD 421
            TY  SPD   ++    G  N  +  G  G+G   A  +G+  +D+    +  FDL    
Sbjct: 308 CTYDNSPDEDFIIDTLPGHDNTLLITGLSGHGFKFASVLGEIAADFAQDKKSDFDLTPFR 367

Query: 422 PNRY 425
            +R+
Sbjct: 368 LSRF 371


>2GAH-C nrPDB
          Length = 210

 Score = 37.0 bits (84), Expect = 0.041,   Method: Composition-based stats.
 Identities = 29/101 (28%), Positives = 45/101 (44%), Gaps = 7/101 (6%)

Query: 580 SPGEFLLITGSGSELHDLRWIEEAAVRGGYDVEIRNITDELGVLGVAGPYARRVLQKLTS 639
           +P EFL  +   +EL  +     +A  G    ++ +++    VL + GP A  VL+K   
Sbjct: 85  APDEFLATSAENTELGGVL----SAALGDAPGQVVDLSANRSVLELTGPDAPLVLRKSCP 140

Query: 640 EDLSDDVFKFLQTKSLKISDIPVTAIRISYTGELGWELYHR 680
            DL    F   Q     +++IPV   R   TGE  W +  R
Sbjct: 141 ADLHPRAFAVNQAIVTSVANIPVLLWR---TGEQAWRIMPR 178


>1KNR-A nrPDB
          Length = 540

 Score = 35.0 bits (79), Expect = 0.16,   Method: Compositional matrix adjust.
 Identities = 19/45 (42%), Positives = 27/45 (60%), Gaps = 2/45 (4%)

Query: 43 AETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAG 87
           + +IIG G  G+SLA  LA      V++L K  +T GST++A G
Sbjct: 9  CDVLIIGSGAAGLSLALRLAD--QHQVIVLSKGPVTEGSTFYAQG 51


>5KXJ-A nrPDB
          Length = 557

 Score = 33.9 bits (76), Expect = 0.35,   Method: Compositional matrix adjust.
 Identities = 18/45 (40%), Positives = 28/45 (62%), Gaps = 2/45 (4%)

Query: 43 AETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAG 87
           + +IIG G  G+SLA  LA+     V++L K  ++ GST++A G
Sbjct: 9  CDVLIIGSGAAGLSLALRLAEK--HKVIVLSKGPVSEGSTFYAQG 51


>4IV9-A nrPDB
          Length = 557

 Score = 33.5 bits (75), Expect = 0.42,   Method: Compositional matrix adjust.
 Identities = 15/39 (38%), Positives = 21/39 (53%)

Query: 45 TVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTW 83
            I+G G  G+  A  L +AG++DVVL E  +   G  W
Sbjct: 41 VAIVGAGISGLVAATELLRAGVKDVVLYESRDRIGGRVW 79


>4C5O-A nrPDB
          Length = 357

 Score = 33.5 bits (75), Expect = 0.44,   Method: Compositional matrix adjust.
 Identities = 17/46 (36%), Positives = 26/46 (56%), Gaps = 2/46 (4%)

Query: 41 DRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAA 86
          D  + V+IGGG  G+S  Y L ++G+  V+L   +E + G  W  A
Sbjct: 2  DSVDVVVIGGGQSGLSAGYFLRRSGLSYVIL--DAEASPGGAWQHA 45


>5MOG-A nrPDB
          Length = 497

 Score = 33.5 bits (75), Expect = 0.46,   Method: Compositional matrix adjust.
 Identities = 27/105 (25%), Positives = 49/105 (46%), Gaps = 13/105 (12%)

Query: 44  ETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGST---------WHAAGLTTYFHP 94
           + VI G G  G+S A +LA AG +  +LLE  ++  G           W+  GL  +F  
Sbjct: 19  QVVIAGAGLAGLSTAKYLADAGHKP-ILLEARDVLGGKIAAWKDEDGDWYETGLHIFFGA 77

Query: 95  GINLKKIHYDSIKLYERLE-EETGQVVGF-HQPGSIRLATTPERV 137
             N++ + +  + + +RL+ +E   +    ++PG       PE +
Sbjct: 78  YPNIQNL-FGELGINDRLQWKEHSMIFAMPNKPGEFSRFDFPETL 121


>6QZO-A nrPDB
          Length = 383

 Score = 32.3 bits (72), Expect = 0.80,   Method: Compositional matrix adjust.
 Identities = 16/37 (43%), Positives = 21/37 (56%), Gaps = 1/37 (2%)

Query: 386 VAIGFGYGIIHAGGVGKYLSDWILHGEPPFDLIELDP 422
           V +GFG G++ A G+      W LH  PPF +  LDP
Sbjct: 101 VTVGFGPGLLTAAGLRHRAPAW-LHPLPPFGIDRLDP 136


>3L1R-A nrPDB
          Length = 478

 Score = 32.3 bits (72), Expect = 0.85,   Method: Compositional matrix adjust.
 Identities = 12/36 (33%), Positives = 24/36 (66%)

Query: 45 TVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAG 80
           +++G G  G+S A  L++AG+ D+++LE ++   G
Sbjct: 7  VIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGG 42


>3S2F-A nrPDB
          Length = 340

 Score = 32.3 bits (72), Expect = 0.97,   Method: Compositional matrix adjust.
 Identities = 16/42 (38%), Positives = 24/42 (57%)

Query: 554 KVGFTNISHMLTPRGRVYAELTVSHQSPGEFLLITGSGSELH 595
           KVGF  I+ +L     VY  L V+   PG++++I+G G   H
Sbjct: 139 KVGFVEIAPILCAGVTVYKGLKVTDTRPGQWVVISGIGGLGH 180


>4UIR-A nrPDB
          Length = 646

 Score = 32.0 bits (71), Expect = 1.1,   Method: Compositional matrix adjust.
 Identities = 18/67 (26%), Positives = 32/67 (47%), Gaps = 3/67 (4%)

Query: 18  QGRPSSAGLREGQESPPSPPEWKDRAETVIIGGGCVGVSLAYHLAKAG---MRDVVLLEK 74
           +  P S  +   Q +   P +  D ++  IIG G  G+S AY+  + G    +++  LE+
Sbjct: 38  KSMPFSDQIGNYQRNKGIPVQSYDNSKIYIIGSGIAGMSAAYYFIRDGHVPAKNITFLEQ 97

Query: 75  SELTAGS 81
             +  GS
Sbjct: 98  LHIDGGS 104


>2JB2-A nrPDB
          Length = 489

 Score = 31.6 bits (70), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 17/42 (40%), Positives = 23/42 (54%), Gaps = 1/42 (2%)

Query: 46 VIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAG 87
          V++GGG  G+  A+ L KAG + V +LE      G  W A G
Sbjct: 15 VVLGGGPAGLCSAFELQKAGYK-VTVLEARTRPGGRVWTARG 55


>3KVE-A nrPDB
          Length = 486

 Score = 31.2 bits (69), Expect = 1.9,   Method: Compositional matrix adjust.
 Identities = 17/35 (48%), Positives = 22/35 (62%), Gaps = 1/35 (2%)

Query: 46 VIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAG 80
          V++G G  G+S AY LA AG + V +LE SE   G
Sbjct: 37 VVVGAGMSGLSAAYVLAGAGHK-VTVLEASERAGG 70


>1F8S-A nrPDB
          Length = 498

 Score = 31.2 bits (69), Expect = 2.1,   Method: Compositional matrix adjust.
 Identities = 18/36 (50%), Positives = 22/36 (61%), Gaps = 1/36 (2%)

Query: 45 TVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAG 80
           VI+G G  G+S AY LA AG + V +LE SE   G
Sbjct: 36 VVIVGAGMAGLSAAYVLAGAGHQ-VTVLEASERPGG 70


>3RHA-A nrPDB
          Length = 482

 Score = 30.8 bits (68), Expect = 2.4,   Method: Compositional matrix adjust.
 Identities = 16/40 (40%), Positives = 23/40 (57%), Gaps = 1/40 (2%)

Query: 44 ETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTW 83
          + VI+G G  G++ A  L KAG+  V +LE  +   G TW
Sbjct: 9  DVVIVGAGPSGLTAARELKKAGLS-VAVLEARDRVGGRTW 47


>4Y4M-A nrPDB
          Length = 290

 Score = 30.8 bits (68), Expect = 2.7,   Method: Compositional matrix adjust.
 Identities = 20/67 (29%), Positives = 35/67 (52%), Gaps = 8/67 (11%)

Query: 7  LRLRGLALRSSQGRPSSAGLREGQESPPSPPEWKD--RAETVIIGGGCVGVSLAYHLAKA 64
          + ++ + L + + + + A L+       S   W D   A+ VI+G G  G++ A +LAK 
Sbjct: 28 MNIKDIKLNADETKTTKAILK------ASFDMWLDIVEADVVIVGAGPSGLTCARYLAKE 81

Query: 65 GMRDVVL 71
          G + VVL
Sbjct: 82 GFKVVVL 88


>1VRQ-C nrPDB
          Length = 206

 Score = 30.8 bits (68), Expect = 2.9,   Method: Composition-based stats.
 Identities = 28/100 (28%), Positives = 41/100 (41%), Gaps = 7/100 (7%)

Query: 581 PGEFLLITGSGSELHDLRWIEEAAVRGGYDVEIRNITDELGVLGVAGPYARRVLQKLTSE 640
           P EFLL       L D          G    ++ +++    VL + GP A  VL+K    
Sbjct: 84  PDEFLLAAEENPALLDTL----QGALGQEPGQVLDLSANRSVLQLEGPAAALVLRKSCPA 139

Query: 641 DLSDDVFKFLQTKSLKISDIPVTAIRISYTGELGWELYHR 680
           DL    F   +  +  +++IPV   R   TGE  W +  R
Sbjct: 140 DLHPREFGVNRAITTSLANIPVLLWR---TGEQSWRILPR 176


>4IVM-B nrPDB
          Length = 483

 Score = 30.4 bits (67), Expect = 3.1,   Method: Compositional matrix adjust.
 Identities = 16/37 (43%), Positives = 24/37 (64%), Gaps = 1/37 (2%)

Query: 45 TVIIGGGCVGVSLAYHLAKAGM-RDVVLLEKSELTAG 80
           V++GGG  G++ +YHL++A     VVL+E SE   G
Sbjct: 11 VVVLGGGISGLAASYHLSRAPCPPKVVLVESSERLGG 47


>4K28-A nrPDB
          Length = 269

 Score = 30.4 bits (67), Expect = 3.2,   Method: Composition-based stats.
 Identities = 15/42 (35%), Positives = 24/42 (57%)

Query: 46  VIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAG 87
           ++IG G VG ++AY LA+AG+  + L + S    G+     G
Sbjct: 129 LVIGCGGVGSAIAYALAEAGIASITLCDPSTARMGAVCELLG 170


>3ATQ-A nrPDB
          Length = 453

 Score = 30.4 bits (67), Expect = 3.7,   Method: Compositional matrix adjust.
 Identities = 24/82 (29%), Positives = 41/82 (50%), Gaps = 11/82 (13%)

Query: 42  RAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKI 101
           + + +IIGGG  G S AY L++ G++  +LL  S+      W+  G       G  + K 
Sbjct: 6   KYDVLIIGGGFAGSSAAYQLSRRGLK--ILLVDSK-----PWNRIGDKP---CGDAVSKA 55

Query: 102 HYDSIKL-YERLEEETGQVVGF 122
           H+D + + Y + EE   ++ G 
Sbjct: 56  HFDKLGMPYPKGEELENKINGI 77


>2IVE-A nrPDB
          Length = 478

 Score = 30.0 bits (66), Expect = 4.4,   Method: Compositional matrix adjust.
 Identities = 15/39 (38%), Positives = 22/39 (56%), Gaps = 1/39 (2%)

Query: 44 ETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGST 82
             ++GGG  G+++A+HL   G  D VLLE S    G+ 
Sbjct: 18 NVAVVGGGISGLAVAHHLRSRGT-DAVLLESSARLGGAV 55


>3RO8-A nrPDB
          Length = 341

 Score = 29.6 bits (65), Expect = 5.1,   Method: Compositional matrix adjust.
 Identities = 15/48 (31%), Positives = 26/48 (54%), Gaps = 4/48 (8%)

Query: 491 KPGQDTQYRPSFRRTNWFRPVGSEY--KQVMQRVGVIDLSPFGKFNIK 536
            P     Y+ S R+T W++ +GS+Y  +  +    V+D +P   +NIK
Sbjct: 143 NPSNPADYKASLRQTPWYQAIGSDYVEQAFLAAREVLDENP--SWNIK 188


>1RP0-A nrPDB
          Length = 284

 Score = 29.6 bits (65), Expect = 5.3,   Method: Compositional matrix adjust.
 Identities = 13/40 (32%), Positives = 22/40 (55%)

Query: 44 ETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTW 83
          + V++G G  G+S AY ++K     V ++E+S    G  W
Sbjct: 41 DVVVVGAGSAGLSAAYEISKNPNVQVAIIEQSVSPGGGAW 80


>5JMD-A nrPDB
          Length = 655

 Score = 29.6 bits (65), Expect = 5.7,   Method: Compositional matrix adjust.
 Identities = 12/33 (36%), Positives = 17/33 (51%)

Query: 484 EQPHWFYKPGQDTQYRPSFRRTNWFRPVGSEYK 516
           E  +W Y P +D + R    R  WF P+G  Y+
Sbjct: 100 EDINWQYWPVKDNELRWQLHRHKWFTPMGKAYR 132


>5Z9A-A nrPDB
          Length = 363

 Score = 29.6 bits (65), Expect = 5.9,   Method: Compositional matrix adjust.
 Identities = 15/50 (30%), Positives = 27/50 (54%), Gaps = 4/50 (8%)

Query: 308 QEKMKLQASWVAHGVPPGFGKELFESDLDRITEHVEAAMEMVPVLKKADI 357
           Q+ +  + + VA GVPPG G+ +F    DR+   +  A+  +  +K  +I
Sbjct: 199 QDSVGAKITVVAEGVPPGLGEPIF----DRLDAELAHALMSINAVKGVEI 244


>3R9U-A nrPDB
          Length = 315

 Score = 29.3 bits (64), Expect = 7.2,   Method: Compositional matrix adjust.
 Identities = 12/31 (38%), Positives = 20/31 (64%)

Query: 44 ETVIIGGGCVGVSLAYHLAKAGMRDVVLLEK 74
          +  IIGGG  G+S   +  + G+++VV+ EK
Sbjct: 6  DVAIIGGGPAGLSAGLYATRGGLKNVVMFEK 36


>1REO-A nrPDB
          Length = 486

 Score = 29.3 bits (64), Expect = 7.2,   Method: Compositional matrix adjust.
 Identities = 16/35 (45%), Positives = 22/35 (62%), Gaps = 1/35 (2%)

Query: 46 VIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAG 80
          V++G G  G+S AY L+ AG + V +LE SE   G
Sbjct: 37 VVVGAGMSGLSAAYVLSGAGHQ-VTVLEASERAGG 70


>4N9X-A nrPDB
          Length = 411

 Score = 28.9 bits (63), Expect = 8.8,   Method: Compositional matrix adjust.
 Identities = 15/31 (48%), Positives = 22/31 (70%), Gaps = 1/31 (3%)

Query: 44 ETVIIGGGCVGVSLAYHLAKAGMRDVVLLEK 74
          + VI GGG VG++LA  L  +G+R + +LEK
Sbjct: 5  DVVIAGGGMVGLALACGLQGSGLR-IAVLEK 34


>6BRD-A nrPDB
          Length = 476

 Score = 28.9 bits (63), Expect = 9.6,   Method: Compositional matrix adjust.
 Identities = 45/159 (28%), Positives = 69/159 (43%), Gaps = 26/159 (16%)

Query: 44  ETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKIHY 103
           + +++GGG  G+ LA  L   G+R +VL +++E T  S             G++++ I  
Sbjct: 3   DVIVVGGGPTGLMLAGELRLHGVRVLVLEKETEPTRQSRAQ----------GLHVRSIEV 52

Query: 104 DSIK-LYERLEE--ETGQVVGFHQPGSIRLATT-PERVDEFKYQMTRTNWHATEQYIIEP 159
            + + L ER  E   T  V GF       LAT+ PER+D     +       TEQ +   
Sbjct: 53  MAQRGLLERFLERGHTVAVGGFFAG----LATSWPERLDTAHSYVLAVPQVITEQLL--A 106

Query: 160 EKIHELFPLLNMDKILAGLYNPGDGHIDPYSLTMALATG 198
           E    L   +   + L GL    DG      +T+ LA G
Sbjct: 107 EHATALGAEIRRGRALVGLRQDEDG------VTVDLADG 139


Searching..................................................done


Results from round 2


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value
Sequences used in model and found again:

4P9S-A nrPDB                                                         1203   0.0  
5L46-A nrPDB                                                         1171   0.0  
1PJ5-A nrPDB                                                          810   0.0  
1YX2-A nrPDB                                                          403   e-112
1WOR-A nrPDB                                                          389   e-108
1V5V-A nrPDB                                                          388   e-108
2GAG-B nrPDB                                                          386   e-107
3GIR-A nrPDB                                                          356   4e-98
1WSR-A nrPDB                                                          354   1e-97
3BHF-A nrPDB                                                          351   1e-96
3AD9-B nrPDB                                                          350   1e-96
3A8J-A nrPDB                                                          345   4e-95
2GAG-A nrPDB                                                          333   2e-91
1ZOV-A nrPDB                                                          331   6e-91
1VRQ-A nrPDB                                                          329   2e-90
3TFJ-A nrPDB                                                          329   4e-90
1NG3-A nrPDB                                                          302   6e-82
3SM8-A nrPDB                                                          292   5e-79
4YSH-A nrPDB                                                          253   3e-67

Sequences not found previously or not previously below threshold:

2UZZ-A nrPDB                                                          186   3e-47
5X1I-A nrPDB                                                          109   6e-24
5XAO-A nrPDB                                                           94   2e-19
3VQR-A nrPDB                                                           81   2e-15
3PVC-A nrPDB                                                           56   8e-08
3PS9-A nrPDB                                                           56   8e-08
5EZ7-A nrPDB                                                           54   3e-07
5KOX-A nrPDB                                                           54   3e-07
3ATQ-A nrPDB                                                           52   1e-06
1QO8-A nrPDB                                                           51   2e-06
3CUK-A nrPDB                                                           50   3e-06
2RGO-A nrPDB                                                           50   5e-06
2RGH-A nrPDB                                                           50   6e-06
1KNR-A nrPDB                                                           49   7e-06
1VE9-A nrPDB                                                           47   4e-05
1RP0-A nrPDB                                                           47   5e-05
3DA1-A nrPDB                                                           46   6e-05
5NCC-A nrPDB                                                           46   7e-05
3ISH-A nrPDB                                                           44   2e-04
3R9U-A nrPDB                                                           44   3e-04
1D4E-A nrPDB                                                           44   3e-04
4DGK-A nrPDB                                                           43   5e-04
5KXJ-A nrPDB                                                           42   7e-04
6BRD-A nrPDB                                                           42   0.001
4C5O-A nrPDB                                                           42   0.001
4REP-A nrPDB                                                           42   0.001
3FPZ-A nrPDB                                                           42   0.001
1C0L-A nrPDB                                                           41   0.002
1F8S-A nrPDB                                                           41   0.002
4BK3-A nrPDB                                                           41   0.002
5MOG-A nrPDB                                                           41   0.003
2BXR-A nrPDB                                                           39   0.006
4Y4M-A nrPDB                                                           39   0.006
1NAA-A nrPDB                                                           39   0.007
5MJK-A nrPDB                                                           39   0.007
5UWY-A nrPDB                                                           39   0.008
4UIR-A nrPDB                                                           39   0.008
1O5W-A nrPDB                                                           39   0.010
3KVE-A nrPDB                                                           39   0.012
2JB2-A nrPDB                                                           39   0.013
3ABT-A nrPDB                                                           38   0.015
3II4-A nrPDB                                                           38   0.015
2CVJ-A nrPDB                                                           38   0.020
2VVL-G nrPDB                                                           37   0.024
5L3D-A nrPDB                                                           37   0.028
3WE0-A nrPDB                                                           37   0.030
1MDA-H nrPDB                                                           37   0.034
5ZYN-B nrPDB                                                           37   0.034
1REO-A nrPDB                                                           37   0.036
1SEZ-A nrPDB                                                           37   0.037
2IVE-A nrPDB                                                           37   0.038
3JSK-A nrPDB                                                           37   0.040
3IHG-A nrPDB                                                           37   0.043
1JWB-B nrPDB                                                           37   0.044
4EIQ-A nrPDB                                                           37   0.044
3MJ4-A nrPDB                                                           37   0.045
3UP5-A nrPDB                                                           37   0.047
4K2X-A nrPDB                                                           37   0.048
3L1R-A nrPDB                                                           37   0.048
4JNQ-A nrPDB                                                           37   0.049
5TUK-A nrPDB                                                           36   0.057
4B1B-A nrPDB                                                           36   0.063
3BI4-A nrPDB                                                           36   0.064
4RPJ-A nrPDB                                                           36   0.069
4IV9-A nrPDB                                                           36   0.069
3NK2-X nrPDB                                                           36   0.077
6J0Z-C nrPDB                                                           36   0.081
4Y4N-A nrPDB                                                           36   0.087
6CR0-A nrPDB                                                           36   0.10 
3RHA-A nrPDB                                                           35   0.11 
4N9X-A nrPDB                                                           35   0.13 
4USR-A nrPDB                                                           35   0.13 
5EVY-X nrPDB                                                           35   0.15 
5TUM-A nrPDB                                                           35   0.15 
3CGD-A nrPDB                                                           35   0.15 
4MOP-A nrPDB                                                           34   0.20 
3LOV-A nrPDB                                                           34   0.23 
6N7F-A nrPDB                                                           34   0.23 
4IA5-A nrPDB                                                           34   0.25 
2Q7V-A nrPDB                                                           34   0.31 
2CUL-A nrPDB                                                           34   0.35 
4OVI-A nrPDB                                                           34   0.36 
1FEC-A nrPDB                                                           34   0.38 
1V59-A nrPDB                                                           33   0.46 
3VH2-A nrPDB                                                           33   0.47 
3T7E-A nrPDB                                                           33   0.47 
4Z25-A nrPDB                                                           33   0.47 
1KSU-A nrPDB                                                           33   0.47 
4OEN-A nrPDB                                                           33   0.54 
3LXD-A nrPDB                                                           33   0.59 
5EQD-A nrPDB                                                           33   0.61 
4X4J-A nrPDB                                                           33   0.62 
4ZN0-A nrPDB                                                           33   0.65 
1ZFN-A nrPDB                                                           33   0.65 
1UXJ-A nrPDB                                                           33   0.69 
2NVK-X nrPDB                                                           33   0.70 
3WSV-A nrPDB                                                           32   0.78 
4NQW-A nrPDB                                                           32   0.82 
4IVM-B nrPDB                                                           32   0.82 
4NTC-A nrPDB                                                           32   0.87 
5Z70-A nrPDB                                                           32   0.95 
6C6P-A nrPDB                                                           32   0.96 
3Q6J-A nrPDB                                                           32   0.97 
6QE4-A nrPDB                                                           32   0.99 
4YNU-A nrPDB                                                           32   1.0  
3LZX-A nrPDB                                                           32   1.0  
4F5M-A nrPDB                                                           32   1.1  
2ZBW-A nrPDB                                                           32   1.2  
1I8T-A nrPDB                                                           32   1.3  
4MO2-B nrPDB                                                           32   1.3  
6GAS-A nrPDB                                                           32   1.3  
1MAF-H nrPDB                                                           32   1.4  
3RED-A nrPDB                                                           32   1.5  
5BR7-A nrPDB                                                           32   1.6  
1DOD-A nrPDB                                                           31   1.7  
2D3L-A nrPDB                                                           31   1.7  
1ZDL-A nrPDB                                                           31   1.8  
2HQM-A nrPDB                                                           31   1.8  
4UDQ-A nrPDB                                                           31   1.9  
4AP1-A nrPDB                                                           31   1.9  
1CSN-A nrPDB                                                           31   2.0  
3RP7-A nrPDB                                                           31   2.2  
3GDN-A nrPDB                                                           31   2.3  
2X3N-A nrPDB                                                           31   2.3  
3B40-A nrPDB                                                           30   3.8  
4HA6-A nrPDB                                                           30   4.0  
2EPJ-A nrPDB                                                           29   7.5  
6AH0-2 nrPDB                                                           29   8.2  
5W1J-A nrPDB                                                           29   8.5  

>4P9S-A nrPDB
          Length = 848

 Score = 1203 bits (3112), Expect = 0.0,   Method: Composition-based stats.
 Identities = 830/836 (99%), Positives = 833/836 (99%)

Query: 22  SSAGLREGQESPPSPPEWKDRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGS 81
           SSAGLREGQESPPSPPEWKDRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGS
Sbjct: 3   SSAGLREGQESPPSPPEWKDRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGS 62

Query: 82  TWHAAGLTTYFHPGINLKKIHYDSIKLYERLEEETGQVVGFHQPGSIRLATTPERVDEFK 141
           TWHAAGLTTYFHPGINLKKIHYDSIKLYERLEEETGQVVGFHQPGSIRLATTPERVDEFK
Sbjct: 63  TWHAAGLTTYFHPGINLKKIHYDSIKLYERLEEETGQVVGFHQPGSIRLATTPERVDEFK 122

Query: 142 YQMTRTNWHATEQYIIEPEKIHELFPLLNMDKILAGLYNPGDGHIDPYSLTMALATGARK 201
           YQMTRTNWHATEQYIIEPEKIHELFPLLNMDKILAGLYNPGDGHIDPYSLTMALATGARK
Sbjct: 123 YQMTRTNWHATEQYIIEPEKIHELFPLLNMDKILAGLYNPGDGHIDPYSLTMALATGARK 182

Query: 202 YGVLLKYPAPVTSLKPRPDGTWDVETPQGSVRANRIVNAAGFWAREVGKMIGLDHPLIPV 261
           YG LLKYPAPVTSLKPRPDGTWDVETPQGSVRANRIVNAAGFWAREVGKMIGLDHPLIPV
Sbjct: 183 YGALLKYPAPVTSLKPRPDGTWDVETPQGSVRANRIVNAAGFWAREVGKMIGLDHPLIPV 242

Query: 262 QHQYVVTSTIPEVKALKRELPVLRDLEGSYYLRQERDGLLFGPYESQEKMKLQASWVAHG 321
           QHQYV+TSTIPEVKALKRELPVLRDLEGSYYLRQERDGLLFGPYESQEKMKLQASWVAHG
Sbjct: 243 QHQYVITSTIPEVKALKRELPVLRDLEGSYYLRQERDGLLFGPYESQEKMKLQASWVAHG 302

Query: 322 VPPGFGKELFESDLDRITEHVEAAMEMVPVLKKADIINIVNGPITYSPDILPMVGPHQGV 381
           VPPGFGKELFESDLDRITEHVEAAMEMVPVLKKADIINIVNGPITYSPDILPMVGPHQGV
Sbjct: 303 VPPGFGKELFESDLDRITEHVEAAMEMVPVLKKADIINIVNGPITYSPDILPMVGPHQGV 362

Query: 382 RNYWVAIGFGYGIIHAGGVGKYLSDWILHGEPPFDLIELDPNRYGKWTTTQYTEAKARES 441
           RNYWVAIGFGYGIIHAGGVG YLSDWILHGEPPFDLIELDPNRYGKWTTTQYTEAKARES
Sbjct: 363 RNYWVAIGFGYGIIHAGGVGTYLSDWILHGEPPFDLIELDPNRYGKWTTTQYTEAKARES 422

Query: 442 YGFNNIVGYPKEERFAGRPTQRVSGLYKILESKCSMGFHAGWEQPHWFYKPGQDTQYRPS 501
           YGFNNIVGYPKEERFAGRPTQRVSGLYKILESKCSMGFHAGWEQPHWFYKPGQDTQYRPS
Sbjct: 423 YGFNNIVGYPKEERFAGRPTQRVSGLYKILESKCSMGFHAGWEQPHWFYKPGQDTQYRPS 482

Query: 502 FRRTNWFRPVGSEYKQVMQRVGVIDLSPFGKFNIKGQDSTQLLDHLCANVIPKVGFTNIS 561
           FRRTNWF PVGSEYKQVMQRVGVIDLSPFGKFNIKGQDSTQLLDHLCANVIPKVGFTNIS
Sbjct: 483 FRRTNWFEPVGSEYKQVMQRVGVIDLSPFGKFNIKGQDSTQLLDHLCANVIPKVGFTNIS 542

Query: 562 HMLTPRGRVYAELTVSHQSPGEFLLITGSGSELHDLRWIEEAAVRGGYDVEIRNITDELG 621
           HMLTPRGRVYAELTVSHQSPGEFLLITGSGSELHDLRWIEEAAVRGGYDVEIRNITDELG
Sbjct: 543 HMLTPRGRVYAELTVSHQSPGEFLLITGSGSELHDLRWIEEAAVRGGYDVEIRNITDELG 602

Query: 622 VLGVAGPYARRVLQKLTSEDLSDDVFKFLQTKSLKISDIPVTAIRISYTGELGWELYHRR 681
           VLGVAGPYARRVLQKLTSEDLSDDVFKFLQTKSLKISDIPVTAIRISYTGELGWELYHRR
Sbjct: 603 VLGVAGPYARRVLQKLTSEDLSDDVFKFLQTKSLKISDIPVTAIRISYTGELGWELYHRR 662

Query: 682 EDSAALYERIMNAGQEEGIDNFGTYALNALRLEKAFRAWGSEMNCDTNPLEAGLDYFIKL 741
           EDSAALYERIMNAGQEEGIDNFGTYALNALRLEKAFRAWGSEMNCDTNPLEAGLDYFIKL
Sbjct: 663 EDSAALYERIMNAGQEEGIDNFGTYALNALRLEKAFRAWGSEMNCDTNPLEAGLDYFIKL 722

Query: 742 NKPADFTGKQALKQIKAKGLKRRLVCLTLATDDVDPEGNESVWYKGKVIGNTTSGSYSYS 801
           NKPA+FTGKQALKQIKAKGLKRRLVCLTLATD+VDPEGNESVWYKGKVIGNTTSGSYSYS
Sbjct: 723 NKPANFTGKQALKQIKAKGLKRRLVCLTLATDNVDPEGNESVWYKGKVIGNTTSGSYSYS 782

Query: 802 IQKSLAFAYVPVELSEVGQQVEVELLGKNYPATIIQEPLVLTEPTRTRLQKDGRKS 857
           IQKSLAFAYVPVELSEVGQQVEVELLGKNYPATIIQEPLVLTEPTRTRLQKDGRKS
Sbjct: 783 IQKSLAFAYVPVELSEVGQQVEVELLGKNYPATIIQEPLVLTEPTRTRLQKDGRKS 838


>5L46-A nrPDB
          Length = 841

 Score = 1171 bits (3029), Expect = 0.0,   Method: Composition-based stats.
 Identities = 769/832 (92%), Positives = 798/832 (95%), Gaps = 2/832 (0%)

Query: 27  REGQESPPSPPE--WKDRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWH 84
           REG+E PP   E  WKDRAETVIIGGGCVGVSLAYHLAKAGM+DVVLLEKSELTAGSTWH
Sbjct: 5   REGEEKPPLSAETQWKDRAETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGSTWH 64

Query: 85  AAGLTTYFHPGINLKKIHYDSIKLYERLEEETGQVVGFHQPGSIRLATTPERVDEFKYQM 144
           AAGLTTYFHPGINLKKIHYDSIKLYE+LEEETGQVVGFHQPGSIRLATTP RVDEFKYQM
Sbjct: 65  AAGLTTYFHPGINLKKIHYDSIKLYEKLEEETGQVVGFHQPGSIRLATTPVRVDEFKYQM 124

Query: 145 TRTNWHATEQYIIEPEKIHELFPLLNMDKILAGLYNPGDGHIDPYSLTMALATGARKYGV 204
           TRT WHATEQY+IEPEKI E+FPLLNM+K+LAGLYNPGDGHIDPYSLTMALA GARK G 
Sbjct: 125 TRTGWHATEQYLIEPEKIQEMFPLLNMNKVLAGLYNPGDGHIDPYSLTMALAAGARKCGA 184

Query: 205 LLKYPAPVTSLKPRPDGTWDVETPQGSVRANRIVNAAGFWAREVGKMIGLDHPLIPVQHQ 264
           LLKYPAPVTSLK R DGTWDVETPQGS+RANRIVNAAGFWAREVGKMIGL+HPLIPVQHQ
Sbjct: 185 LLKYPAPVTSLKARSDGTWDVETPQGSMRANRIVNAAGFWAREVGKMIGLEHPLIPVQHQ 244

Query: 265 YVVTSTIPEVKALKRELPVLRDLEGSYYLRQERDGLLFGPYESQEKMKLQASWVAHGVPP 324
           YVVTSTIPEVKALKRELPVLRDLEGSYYLRQERDGLLFGPYESQEKMK+Q SWV +GVPP
Sbjct: 245 YVVTSTIPEVKALKRELPVLRDLEGSYYLRQERDGLLFGPYESQEKMKVQDSWVTNGVPP 304

Query: 325 GFGKELFESDLDRITEHVEAAMEMVPVLKKADIINIVNGPITYSPDILPMVGPHQGVRNY 384
           GFGKELFESDLDRI EH++AAMEMVPVLKKADIIN+VNGPITYSPDILPMVGPHQGVRNY
Sbjct: 305 GFGKELFESDLDRIMEHIKAAMEMVPVLKKADIINVVNGPITYSPDILPMVGPHQGVRNY 364

Query: 385 WVAIGFGYGIIHAGGVGKYLSDWILHGEPPFDLIELDPNRYGKWTTTQYTEAKARESYGF 444
           WVAIGFGYGIIHAGGVGKYLSDWILHGEPPFDLIELDPNRYGKWTTTQYTEAKARESYGF
Sbjct: 365 WVAIGFGYGIIHAGGVGKYLSDWILHGEPPFDLIELDPNRYGKWTTTQYTEAKARESYGF 424

Query: 445 NNIVGYPKEERFAGRPTQRVSGLYKILESKCSMGFHAGWEQPHWFYKPGQDTQYRPSFRR 504
           NNIVGYPKEERFAGRPTQRVSGLY+ LESKCSMGFHAGWEQPHWFYKPGQDTQYRPSFRR
Sbjct: 425 NNIVGYPKEERFAGRPTQRVSGLYQRLESKCSMGFHAGWEQPHWFYKPGQDTQYRPSFRR 484

Query: 505 TNWFRPVGSEYKQVMQRVGVIDLSPFGKFNIKGQDSTQLLDHLCANVIPKVGFTNISHML 564
           TNWF PVGSEYKQVMQRV V DLSPFGKFNIKGQDS +LLDHL ANVIPKVGFTNISHML
Sbjct: 485 TNWFEPVGSEYKQVMQRVAVTDLSPFGKFNIKGQDSIRLLDHLFANVIPKVGFTNISHML 544

Query: 565 TPRGRVYAELTVSHQSPGEFLLITGSGSELHDLRWIEEAAVRGGYDVEIRNITDELGVLG 624
           TP+GRVYAELTVSHQSPGEFLLITGSGSELHDLRWIEE AV+GGYDVEI+NITDELGVLG
Sbjct: 545 TPKGRVYAELTVSHQSPGEFLLITGSGSELHDLRWIEEEAVKGGYDVEIKNITDELGVLG 604

Query: 625 VAGPYARRVLQKLTSEDLSDDVFKFLQTKSLKISDIPVTAIRISYTGELGWELYHRREDS 684
           VAGP AR+VLQKLTSEDLSDDVFKFLQTKSLK+S+IPVTAIRISYTGELGWELYHRREDS
Sbjct: 605 VAGPQARKVLQKLTSEDLSDDVFKFLQTKSLKVSNIPVTAIRISYTGELGWELYHRREDS 664

Query: 685 AALYERIMNAGQEEGIDNFGTYALNALRLEKAFRAWGSEMNCDTNPLEAGLDYFIKLNKP 744
            ALY+ IMNAGQEEGIDNFGTYA+NALRLEKAFRAWG EMNCDTNPLEAGL+YF+KLNKP
Sbjct: 665 VALYDAIMNAGQEEGIDNFGTYAMNALRLEKAFRAWGLEMNCDTNPLEAGLEYFVKLNKP 724

Query: 745 ADFTGKQALKQIKAKGLKRRLVCLTLATDDVDPEGNESVWYKGKVIGNTTSGSYSYSIQK 804
           ADF GKQALKQIKAKGLKRRLVCLTLATDDVDPEGNES+WY GKV+GNTTSGSYSYSIQK
Sbjct: 725 ADFIGKQALKQIKAKGLKRRLVCLTLATDDVDPEGNESIWYNGKVVGNTTSGSYSYSIQK 784

Query: 805 SLAFAYVPVELSEVGQQVEVELLGKNYPATIIQEPLVLTEPTRTRLQKDGRK 856
           SLAFAYVPV+LSEVGQQVEVELLGKNYPA IIQEPLVLTEPTR RLQK G K
Sbjct: 785 SLAFAYVPVQLSEVGQQVEVELLGKNYPAVIIQEPLVLTEPTRNRLQKKGGK 836


>1PJ5-A nrPDB
          Length = 830

 Score =  810 bits (2091), Expect = 0.0,   Method: Composition-based stats.
 Identities = 241/837 (28%), Positives = 404/837 (48%), Gaps = 44/837 (5%)

Query: 45  TVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSEL--TAGSTWHAAGLTTYFHPGINLKKIH 102
            VIIG G VG +LA  L   G  ++ +L++  L    GST HA GL    +P   +    
Sbjct: 7   IVIIGAGIVGTNLADELVTRGWNNITVLDQGPLNMPGGSTSHAPGLVFQTNPSKTMASFA 66

Query: 103 YDSIKLYERLEEETGQVVGFHQPGSIRLATTPERVDEFKYQMTRTNWHATEQYIIEPEKI 162
             +++    L E+   V  F+Q G + +ATT  R+ + K ++        E  ++ P + 
Sbjct: 67  KYTVEKLLSLTED--GVSCFNQVGGLEVATTETRLADLKRKLGYAAAWGIEGRLLSPAEC 124

Query: 163 HELFPLLNMDKILAGLYNPGDGHIDPYSLTMALATGARKYGVLLKYPAPVTSLKPRPDGT 222
            EL+PLL+ + IL GL+ P DG          L       GV  +    VT ++      
Sbjct: 125 QELYPLLDGENILGGLHVPSDGLASAARAVQLLIKRTESAGVTYRGSTTVTGIEQSGGRV 184

Query: 223 WDVETPQGSVRANRIVNAAGFWAREVGKMIGLDHPLIPVQHQYVVTSTIPEVKALKRE-- 280
             V+T  G + A+ +V+ AGFW  ++G MIG+  PL+P+ HQYV T+ +P  +    +  
Sbjct: 185 TGVQTADGVIPADIVVSCAGFWGAKIGAMIGMAVPLLPLAHQYVKTTPVPAQQGRNDQPN 244

Query: 281 ---LPVLRDLEGSYYLRQERDGLLFGPYESQEKMKLQASWVAHGVPPGFGKELFESDLDR 337
              LP+LR  +   Y R+  D    G Y +   M +    +    P    +    S LD 
Sbjct: 245 GARLPILRHQDQDLYYREHGDRYGIGSY-AHRPMPVDVDTLGAYAPETVSEHHMPSRLDF 303

Query: 338 ITEHV----EAAMEMVPVLKKADIINIVNGPITYSPDILPMVGPHQGVRNYWVAIGFGYG 393
             E      EA  +++P L  ++I +  NG  +++PD  P++G  + +  ++VA      
Sbjct: 304 TLEDFLPAWEATKQLLPALADSEIEDGFNGIFSFTPDGGPLLGESKELDGFYVAEAVW-- 361

Query: 394 IIHAGGVGKYLSDWILHGEPPFDLIELDPNRYGKWTTT-QYTEAKARESYGFNNIVGYPK 452
           + H+ GV K +++ +  G    DL E D  R+     T +Y    +++++     V +P 
Sbjct: 362 VTHSAGVAKAMAELLTTGRSETDLGECDITRFEDVQLTPEYVSETSQQNFVEIYDVLHPL 421

Query: 453 EERFAGRPTQRVSGLYKILESKCSMGFHA-GWEQPHWFYKPGQDTQYRPSFRRTNWFRPV 511
           + R + R   RVS  +   +   +    A GWE+P+WF       +  P+     W  P 
Sbjct: 422 QPRLSPR-NLRVSPFHARHKELGAFFLEAGGWERPYWFEANAALLKEMPA----EWLPPA 476

Query: 512 GS-------------EYKQVMQRVGVIDLSPFGKFNIKGQDSTQLLDHLCANVIP-KVGF 557
                          E  +    V + D++P  +  + G  + +LL  L    +  K G 
Sbjct: 477 RDAWSGMFSSPIAAAEAWKTRTAVAMYDMTPLKRLEVSGPGALKLLQELTTADLAKKPGA 536

Query: 558 TNISHMLTPRGRVYAELTVSHQSPGEFLLITGSGSELHDLRWIEEAAVRGGYD---VEIR 614
              + +L   G V +++TV+  S   F L      +            + G     V++R
Sbjct: 537 VTYTLLLDHAGGVRSDITVARLSEDTFQLGANGNIDTAYFERAARHQTQSGSATDWVQVR 596

Query: 615 NITDELGVLGVAGPYARRVLQKLTSEDLSDDVFKFLQTKSLKISDIPVTAIRISYTGELG 674
           + T     +G+ GP AR ++ K++ +D ++D  K+ + K++ I  IPVTA+R+SY GELG
Sbjct: 597 DTTGGTCCIGLWGPLARDLVSKVSDDDFTNDGLKYFRAKNVVIGGIPVTAMRLSYVGELG 656

Query: 675 WELYHRREDSAALYERIMNAGQEEGIDNFGTYALNALRLEKAFRAWGSEMNCDTNPLEAG 734
           WELY   ++   L++ +  AGQ  G+   G  A ++LRLEK +R+WG++M  + +P EAG
Sbjct: 657 WELYTSADNGQRLWDALWQAGQPFGVIAAGRAAFSSLRLEKGYRSWGTDMTTEHDPFEAG 716

Query: 735 LDYFIKLNKPADFTGKQALKQIKAKGLKRRLVCLTLATDDVDPEGNESVWYKGKVIGNTT 794
           L + +K+ K + F GK AL+    +   RRL CLT+        G E V+YK + +G  T
Sbjct: 717 LGFAVKMAKES-FIGKGALEGRTEEASARRLRCLTIDDGRSIVLGKEPVFYKEQAVGYVT 775

Query: 795 SGSYSYSIQKSLAFAYVPVELSEVGQQVEVELLGKNYPATIIQEPLVLTEPTRTRLQ 851
           S +Y Y++ K +A++Y+P  +S VG  V++E  G+   AT+ ++PL   +P  TRL+
Sbjct: 776 SAAYGYTVAKPIAYSYLPGTVS-VGDSVDIEYFGRRITATVTEDPLY--DPKMTRLR 829


>1YX2-A nrPDB
          Length = 365

 Score =  403 bits (1035), Expect = e-112,   Method: Composition-based stats.
 Identities = 110/384 (28%), Positives = 180/384 (46%), Gaps = 29/384 (7%)

Query: 462 QRVSGLYKILES-KCSMGFHAGWEQPHWFYKPGQDTQYRPSFRRTNWFRPVGSEYKQVMQ 520
            + + L+ + +          GWE P                     F  +  E++ V  
Sbjct: 5   LKRTPLFDLYKEYGGKTIDFGGWELPVQ-------------------FSSIKKEHEAVRT 45

Query: 521 RVGVIDLSPFGKFNIKGQDSTQLLDHLCANVIPK--VGFTNISHMLTPRGRVYAELTVSH 578
             G+ D+S  G+  + G DS   L  L  N +     G    + M  P G    +L +  
Sbjct: 46  AAGLFDVSHMGEVEVSGNDSLSFLQRLMTNDVSALTPGRAQYTAMCYPDGGTVDDLLIYQ 105

Query: 579 QSPGEFLLITGSGSELHDLRWIEEAAVRGGYDVEIRNITDELGVLGVAGPYARRVLQKLT 638
           +    +LL+  + +   DL W++E A     DV+I N +D++ +L V GP A  +L+ LT
Sbjct: 106 KGENRYLLVINASNIDKDLAWMKEHAAG---DVQIDNQSDQIALLAVQGPKAEAILKNLT 162

Query: 639 SEDLSD-DVFKFLQTKSLKISDIPVTAIRISYTGELGWELYHRREDSAALYERIMNAGQE 697
             D+S    F F+      IS       R  YTGE G+E+Y R +D+  ++++I++AG  
Sbjct: 163 DADVSALKPFAFIDEAD--ISGRKALISRTGYTGEDGYEIYCRSDDAMHIWKKIIDAGDA 220

Query: 698 EGIDNFGTYALNALRLEKAFRAWGSEMNCDTNPLEAGLDYFIKLNKPADFTGKQALKQIK 757
            G+   G  A + LR E     +G E+  D  P+EAG+ + +K  K +DF GK  L + K
Sbjct: 221 YGLIPCGLGARDTLRFEANIPLYGQELTRDITPIEAGIGFAVKHKKESDFFGKSVLSEQK 280

Query: 758 AKGLKRRLVCLTLATDDVDPEGNESVWYKGKVIGNTTSGSYSYSIQKSLAFAYVPVELSE 817
             G KR+LV L +    +   G E V+  GK +G  T+G+ S ++ K++  A +  E SE
Sbjct: 281 ENGAKRKLVGLEMIEKGIPRHGYE-VFQNGKSVGKVTTGTQSPTLGKNVGLALIDSETSE 339

Query: 818 VGQQVEVELLGKNYPATIIQEPLV 841
           +G  V+VE+  K   A +++ P  
Sbjct: 340 IGTVVDVEIRKKLVKAKVVKTPFY 363


>1WOR-A nrPDB
          Length = 364

 Score =  389 bits (998), Expect = e-108,   Method: Composition-based stats.
 Identities = 114/386 (29%), Positives = 191/386 (49%), Gaps = 35/386 (9%)

Query: 462 QRVSGLYKILESKCSMGFHAGWEQPHWFYKPGQDTQYRPSFRRTNWFRPVGSEYKQVMQR 521
           +R     K +E    M   AGWE P ++                     +  E   V + 
Sbjct: 2   KRTPLFEKHVELGAKMVDFAGWEMPLYY-------------------TSIFEEVMAVRKS 42

Query: 522 VGVIDLSPFGKFNIKGQDSTQLLDHLCANVIPKV--GFTNISHMLTPRGRVYAELTVSHQ 579
           VG+ D+S  G+F +KG ++   +D L  N    +  G    S M    G +  +L V   
Sbjct: 43  VGMFDVSHMGEFLVKGPEAVSFIDFLITNDFSSLPDGKAIYSVMCNENGGIIDDLVVYKV 102

Query: 580 SPGEFLLITGSGSELHDLRWIEEAAVRGGYDVEIRNITDELGVLGVAGPYARRVLQKLTS 639
           SP E L++  + +   D  WI+  +    +DVE+ NI+D   ++   GP A+  LQ+L  
Sbjct: 103 SPDEALMVVNAANIEKDFNWIKSHS--KNFDVEVSNISDTTALIAFQGPKAQETLQELV- 159

Query: 640 EDLSDDVFKFLQTKSLKISDIPVTAIRISYTGELGWELYHRREDSAALYERIMNAGQEEG 699
           ED  +++  +   KS+ ++ +     R  YTGE G+EL    +++  +++ +MN  ++  
Sbjct: 160 EDGLEEIAYYSFRKSI-VAGVETLVSRTGYTGEDGFELMLEAKNAPKVWDALMNLLRKID 218

Query: 700 IDNFGTYALNALRLEKAFRAWGSEMNCDTNPLEAGLDYFIKLNKPADFTGKQALKQIKAK 759
               G  A +  RLE  +  +G +M+ +TNP E GL + +KLNK  DF GK+AL + K K
Sbjct: 219 GRPAGLGARDVCRLEATYLLYGQDMDENTNPFEVGLSWVVKLNK--DFVGKEALLKAKEK 276

Query: 760 GLKRRLVCLTLATDDVDPEGNESVWYKGKVIGNTTSGSYSYSIQKSLAFAYVPVELSEVG 819
            ++R+LV L L+   +  +G E V   G+ +G  TSG++S ++ KS+A A V   + ++G
Sbjct: 277 -VERKLVALELSGKRIARKGYE-VLKNGERVGEITSGNFSPTLGKSIALALVSKSV-KIG 333

Query: 820 QQVEVELLGKNYPATIIQEPLVLTEP 845
            Q     LG  +P   + E LV+ +P
Sbjct: 334 DQ-----LGVVFPGGKLVEALVVKKP 354


>1V5V-A nrPDB
          Length = 401

 Score =  388 bits (995), Expect = e-108,   Method: Composition-based stats.
 Identities = 107/421 (25%), Positives = 185/421 (43%), Gaps = 55/421 (13%)

Query: 462 QRVSGLYKILESKCSMGFHAGWEQPHWFYKPGQDTQYRPSFRRTNWFRPVGSEYKQVMQR 521
           +RV       E    +   AGWE P W+                     +  E+  V   
Sbjct: 6   KRVHIFDWHKEHARKIEEFAGWEMPIWY-------------------SSIKEEHLAVRNA 46

Query: 522 VGVIDLSPFGKFNIKGQDSTQLLDHLCANVIPKVGF--TNISHMLTPRGRVYAELTVSHQ 579
           VG+ D+S  G+   +G+D+ + L ++  N I K        + +L  RG +  E  V + 
Sbjct: 47  VGIFDVSHMGEIVFRGKDALKFLQYVTTNDISKPPAISGTYTLVLNERGAIKDETLVFNM 106

Query: 580 SPGEFLLITGSGSELHDLRWIE----EAAVRGGYDVEIRNITDELGVLGVAGPYARRVLQ 635
              E+L+I  S +      W              D+EI   T ++ +  V GP AR + +
Sbjct: 107 GNNEYLMICDSDAFEKLYAWFTYLKRTIEQFTKLDLEIELKTYDIAMFAVQGPKARDLAK 166

Query: 636 KLTSEDLSDDVFKFLQTKSLKISDIPVTAIRISYTGELGWELYHRR-------------- 681
            L   D+++    + Q + +++  I +   R  YTGE G+E+Y                 
Sbjct: 167 DLFGIDINE--MWWFQARWVELDGIKMLLSRSGYTGENGFEVYIEDANPYHPDESKRGEP 224

Query: 682 EDSAALYERIMNAGQEEGIDNFGTYALNALRLEKAFRAWGSEMNC---------DTNPLE 732
           E +  ++ERI+  G++ GI   G  A + LRLE  +  +G+E            +  PL+
Sbjct: 225 EKALHVWERILEEGKKYGIKPCGLGARDTLRLEAGYTLYGNETKELQLLSTDIDEVTPLQ 284

Query: 733 AGLDYFIKLNKPADFTGKQALKQIKAKGLKRRLVCLTLATDDVDPEGNESVWYKGKVIGN 792
           A L++ I  +K  DF GK AL + K +G+ R+LV   +    +  EG + V+  G++IG 
Sbjct: 285 ANLEFAIYWDK--DFIGKDALLKQKERGVGRKLVHFKMIDKGIPREGYK-VYANGEMIGE 341

Query: 793 TTSGSYSYSIQKSLAFAYVPVELSEVGQQVEVELLGKNYPATIIQEPLVLTEPTRTRLQK 852
            TSG+ S  +   +  A+V  E ++ G ++EVE+ G+   A  +  P    +P +  L +
Sbjct: 342 VTSGTLSPLLNVGIGIAFVKEEYAKPGIEIEVEIRGQRKKAVTVTPPFY--DPKKYGLFR 399

Query: 853 D 853
           +
Sbjct: 400 E 400


>2GAG-B nrPDB
          Length = 405

 Score =  386 bits (990), Expect = e-107,   Method: Composition-based stats.
 Identities = 89/399 (22%), Positives = 160/399 (40%), Gaps = 33/399 (8%)

Query: 37  PEWKDRAETVIIGGGCVGVSLAYHLAK-AGMRDVVLLEKSELTAGSTWHAAGLTTYFHPG 95
           PE K   + +I+GGG  G++ AY LAK  G+ +V +LEK  L  G+      +    +  
Sbjct: 16  PEPKKSYDAIIVGGGGHGLATAYFLAKNHGITNVAVLEKGWLAGGNMARNTTIIRSNYLW 75

Query: 96  INLKKIHYDSIKLYERLEEETGQVVGFHQPGSIRLATTPERVDEFKYQMTRTNWHATEQY 155
                I+  S+KL+E+L E+      F Q G + LA T   V E   ++     +  +  
Sbjct: 76  DESAGIYEKSLKLWEQLPEDLEYDFLFSQRGVLNLAHTLGDVRESVRRVEANKLNGVDAE 135

Query: 156 IIEPEKIHELFPLLNMDK-----ILAGLYNPGDGHIDPYSLTMALATGARKYGVLLKYPA 210
            ++P ++ E  P++N        ++   + P  G      +  A A  A + GV +    
Sbjct: 136 WLDPSQVKEACPIINTSDDIRYPVMGATWQPRAGIAKHDHVAWAFARKANEMGVDIIQNC 195

Query: 211 PVTSLKPRPDGTWDVETPQGSVRANRIVNAAGFWAREVGKMIGLDHPLIPVQHQYVVTST 270
            VT      +    V+T +G++ A ++  A    +  + +M G + P+     Q +V+  
Sbjct: 196 EVTGFIKDGEKVTGVKTTRGTIHAGKVALAGAGHSSVLAEMAGFELPIQSHPLQALVSEL 255

Query: 271 IPEVKALKRELPVLRDLEGSYYLRQERDGLLFGPYESQEKMKLQASWVAHGVPP--GFGK 328
              V        V+       Y+ Q   G L                +  G+    G+G+
Sbjct: 256 FEPVHPT-----VVMSNHIHVYVSQAHKGELV---------------MGAGIDSYNGYGQ 295

Query: 329 ELFESDLDRITEHVEAAMEMVPVLKKADIINIVNGPITYSPDILPMVGPHQGVRNYWVAI 388
                    I E + AA+E+ P+  +A ++    G +  + D  P++     ++N +V  
Sbjct: 296 ---RGAFHVIQEQMAAAVELFPIFARAHVLRTWGGIVDTTMDASPIISK-TPIQNLYVNC 351

Query: 389 GFGYGIIHA-GGVGKYLSDWILHGEPPFDLIELDPNRYG 426
           G+G G      G G  L+  I + EP          R+ 
Sbjct: 352 GWGTGGFKGTPGAGFTLAHTIANDEPHELNKPFSLERFE 390


>3GIR-A nrPDB
          Length = 393

 Score =  356 bits (912), Expect = 4e-98,   Method: Composition-based stats.
 Identities = 95/386 (24%), Positives = 158/386 (40%), Gaps = 36/386 (9%)

Query: 461 TQRVSGLYKILE-SKCSMGFHAGWEQPHWFYKPGQDTQYRPSFRRTNWFRPVGSEYKQVM 519
           + +   LY++ E +    G  AGW  P  +                     V  E+    
Sbjct: 32  SLKTLPLYELHEKAGAKFGAFAGWRMPLTYP------------------LGVLKEHLHTR 73

Query: 520 QRVGVIDLSPFGKFNIKGQDSTQLLDHL--CANVIPKVGFTNISHMLTPRGRVYAELTVS 577
              G+ D+S      ++G  + + L +       + K+G +  S++L  R  +  +L ++
Sbjct: 74  AHAGLFDISHMKLIAVEGPKAVEFLSYALPVDAALLKIGQSRYSYLLNERAGILDDLILT 133

Query: 578 HQSPGEFLLITGSGSELHDLRWIEEAAVRGGYDVEIRNITDELGVLGVAGPYARRVLQKL 637
             +   F+L+  +G+   D   +E+ A    +  E + I  E  +L + GP A  V   L
Sbjct: 134 RLAECRFMLVANAGNAQADFAELEKRA----FGFECQVIALERVLLALQGPQAAAV---L 186

Query: 638 TSEDLSDDVFKFLQTKSLKISDIPVTAIRISYTGELGWELYHRREDSAALYERIMNAGQE 697
               L  +   F+Q    +  D      R  YTGE G+E+      + AL E+++   + 
Sbjct: 187 ADAGLPGNELLFMQGFEPQ-QDWF--ITRSGYTGEDGFEIALPIGCARALAEKLLGDSRV 243

Query: 698 EGIDNFGTYALNALRLEKAFRAWGSEMNCDTNPLEAGLDYFIKLN--KPADFTGKQALKQ 755
           E +   G  A ++LRLE      G+++  DT P++A L + +  N  + A F G +A  +
Sbjct: 244 EWV---GLAARDSLRLEAGLCLHGNDITPDTTPIDAALTWAVPKNVREKAQFYGAKAFLE 300

Query: 756 IKAKGLKRRLVCLTLATDDVDPEGNESVWYKGKVIGNTTSGSYSYSIQKSLAFAYVPVEL 815
              KG  R  V L   T      G      +G  IG  TSG +  S    +A  YVPV  
Sbjct: 301 SLQKGPSRCRVGLKPQTRQPIRAGAVLFDNEGNRIGVVTSGGFGPSFDGPVAMGYVPVAW 360

Query: 816 SEVGQQVEVELLGKNYPATIIQEPLV 841
              G +V  EL GK    ++   P V
Sbjct: 361 KVEGTEVFTELRGKKIALSVHSLPFV 386


>1WSR-A nrPDB
          Length = 375

 Score =  354 bits (907), Expect = 1e-97,   Method: Composition-based stats.
 Identities = 100/395 (25%), Positives = 166/395 (42%), Gaps = 41/395 (10%)

Query: 462 QRVSGLYK-ILESKCSMGFHAGWEQPHWFYKPGQDTQYRPSFRRTNWFRPVGSEYKQVMQ 520
            R + LY   L     M   AGW  P          QYR S   +         +    Q
Sbjct: 5   LRRTPLYDFHLAHGGKMVAFAGWSLP---------VQYRDSHTDS---------HLHTRQ 46

Query: 521 RVGVIDLSPFGKFNIKGQDSTQLLDHLCANVI--PKVGFTNISHMLTPRGRVYAELTVSH 578
              + D+S   +  I G D  +L++ L    I   +     +S      G +  +L V++
Sbjct: 47  HCSLFDVSHMLQTKILGSDRVKLMESLVVGDIAELRPNQGTLSLFTNEAGGILDDLIVTN 106

Query: 579 QSPGEFLLITGSGSELHDLRWIEEAA---VRGGYDVEIRNITDELGVLGVAGPYARRVLQ 635
            S G   +++ +G    DL  +++        G DV +  + +   +L + GP A +VLQ
Sbjct: 107 TSEGHLYVVSNAGCWEKDLALMQDKVRELQNQGRDVGLEVLDN--ALLALQGPTAAQVLQ 164

Query: 636 KLTSEDLSDDVFKFLQTKSLKISDIP-VTAIRISYTGELGWELYHRREDSAALYERIMNA 694
              ++DL      F+ +  +++  +      R  YTGE G E+      +  L   I+  
Sbjct: 165 AGVADDLRK--LPFMTSAVMEVFGVSGCRVTRCGYTGEDGVEISVPVAGAVHLATAILKN 222

Query: 695 GQEEGIDNFGTYALNALRLEKAFRAWGSEMNCDTNPLEAGLDYFIKLNKPA--DFTG-KQ 751
            +   +   G  A ++LRLE     +G++++  T P+E  L + +   + A  DF G K 
Sbjct: 223 PE---VKLAGLAARDSLRLEAGLCLYGNDIDEHTTPVEGSLSWTLGKRRRAAMDFPGAKV 279

Query: 752 ALKQIKAKGLKRR--LVCLTLATDDVDPEGNESVWYKGKVIGNTTSGSYSYSIQKSLAFA 809
            + Q+K +  +RR  L+C         P  N     +G  IG  TSG  S S++K++A  
Sbjct: 280 IVPQLKGRVQRRRVGLMCEGAPMRAHSPILN----MEGTKIGTVTSGCPSPSLKKNVAMG 335

Query: 810 YVPVELSEVGQQVEVELLGKNYPATIIQEPLVLTE 844
           YVP E S  G  + VE+  K   A + + P V T 
Sbjct: 336 YVPCEYSRPGTMLLVEVRRKQQMAVVSKMPFVPTN 370


>3BHF-A nrPDB
          Length = 390

 Score =  351 bits (899), Expect = 1e-96,   Method: Composition-based stats.
 Identities = 81/391 (20%), Positives = 156/391 (39%), Gaps = 26/391 (6%)

Query: 43  AETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAG--LTTYFHPGINLKK 100
            + +++G G +G++  Y LAK G++ +++          + H     +   +  G     
Sbjct: 5   FDVIVVGAGSMGMAAGYQLAKQGVKTLLVDAFDPPHTNGSHHGDTKIIRHAYGEGREYVP 64

Query: 101 IHYDSIKLYERLEEETGQVVGFHQPGSIRLATTPERVDEFKYQ-MTRTNWHATEQYIIEP 159
           +   S +L+  LE+ET   + F + G   L   P+    F  + M     H+    ++E 
Sbjct: 65  LALRSQELWYELEKETHHKI-FTKTGV--LVFGPKGESAFVAETMEAAKEHSLTVDLLEG 121

Query: 160 EKIHELFPLLNMDKILAGLYNPGDGHIDPYSLTMALATGARKYGVLLKYPAPVTSLKPRP 219
           ++I++ +P + + +    ++ P  G +   +   A    A   G  +     V      P
Sbjct: 122 DEINKRWPGITVPENYNAIFEPNSGVLFSENCIRAYRELAEARGAKVLTHTRVEDFDISP 181

Query: 220 DGTWDVETPQGSVRANRIVNAAGFWAREVGKMIGLDHPLIPVQHQYVVTSTIPEVKALKR 279
           D +  +ET  GS  A++++ + G W  ++   + LD PL P + Q V      E K    
Sbjct: 182 D-SVKIETANGSYTADKLIVSMGAWNSKLLSKLNLDIPLQPYR-QVVGFFESDESK---- 235

Query: 280 ELPVLRDLEGSYYLRQERDGLLFG-PYESQEKMKLQASWVAHGVPPGFGKE---LFESDL 335
                 D++   ++ +  +G+ +G P      +KL        + P        ++  D 
Sbjct: 236 ---YSNDIDFPGFMVEVPNGIYYGFPSFGGCGLKLGYHTFGQKIDPDTINREFGVYPEDE 292

Query: 336 DRITEHVEAAMEMVP-VLKKADIINIVNGPITYSPDILPMVGPHQGVRNYWVAIGF-GYG 393
             +   +E  M      LK+  +        T + D   ++  H    N  +A GF G+G
Sbjct: 293 SNLRAFLEEYMPGANGELKRGAVCM-----YTKTLDEHFIIDLHPEHSNVVIAAGFSGHG 347

Query: 394 IIHAGGVGKYLSDWILHGEPPFDLIELDPNR 424
              + GVG+ LS   L G+   D+     NR
Sbjct: 348 FKFSSGVGEVLSQLALTGKTEHDISIFSINR 378


>3AD9-B nrPDB
          Length = 404

 Score =  350 bits (898), Expect = 1e-96,   Method: Composition-based stats.
 Identities = 93/399 (23%), Positives = 162/399 (40%), Gaps = 33/399 (8%)

Query: 37  PEWKDRAETVIIGGGCVGVSLAYHLAK-AGMRDVVLLEKSELTAGSTWHAAGLTTYFHPG 95
           PE K   + VI+GGG  G++ AY+LAK  G+ +V +LEK  L  G+      +    +  
Sbjct: 15  PEPKKSYDVVIVGGGGHGLATAYYLAKNHGITNVAVLEKGWLAGGNMARNTTIIRSNYLW 74

Query: 96  INLKKIHYDSIKLYERLEEETGQVVGFHQPGSIRLATTPERVDEFKYQMTRTNWHATEQY 155
                I+  S+KL+E L EE      F Q G + LA T   V E   ++    ++  +  
Sbjct: 75  DESAGIYEKSLKLWEELPEELEYDFLFSQRGVLNLAHTLGDVRESIRRVEANKFNGVDAE 134

Query: 156 IIEPEKIHELFPLLNMDK-----ILAGLYNPGDGHIDPYSLTMALATGARKYGVLLKYPA 210
            + PE++ E+ P++N        ++   Y P  G      +  A A  A + GV +    
Sbjct: 135 WLTPEQVKEVCPIINTGDNIRYPVMGATYQPRAGIAKHDHVAWAFARKANEMGVDIIQNC 194

Query: 211 PVTSLKPRPDGTWDVETPQGSVRANRIVNAAGFWAREVGKMIGLDHPLIPVQHQYVVTST 270
            VT      +    V+T +G++ A ++  A    +  + ++ G + P+     Q +V+  
Sbjct: 195 EVTGFLKDGEKVTGVKTTRGTILAGKVALAGAGHSSVLAELAGFELPIQSHPLQALVSEL 254

Query: 271 IPEVKALKRELPVLRDLEGSYYLRQERDGLLFGPYESQEKMKLQASWVAHGVPP--GFGK 328
              V        V+       Y+ Q   G L                +  G+    G+G+
Sbjct: 255 FEPVHPT-----VVMSNHIHVYVSQAHKGELV---------------MGAGIDSYNGYGQ 294

Query: 329 ELFESDLDRITEHVEAAMEMVPVLKKADIINIVNGPITYSPDILPMVGPHQGVRNYWVAI 388
                    I E + AA+E+ P+  +A ++    G +  + D  P++     ++N +V  
Sbjct: 295 ---RGAFHVIEEQMAAAVELFPIFARAHVLRTWGGIVDTTMDASPIISK-TPIQNLYVNC 350

Query: 389 GFGYGIIHA-GGVGKYLSDWILHGEPPFDLIELDPNRYG 426
           G+G G      G G  L+  I H EP          R+ 
Sbjct: 351 GWGTGGFKGTPGAGYTLAHTIAHDEPHKLNAPFALERFE 389


>3A8J-A nrPDB
          Length = 364

 Score =  345 bits (885), Expect = 4e-95,   Method: Composition-based stats.
 Identities = 94/392 (23%), Positives = 161/392 (41%), Gaps = 54/392 (13%)

Query: 465 SGLYKILES-KCSMGFHAGWEQPHWFYKPGQDTQYRPSFRRTNWFRPVGSEYKQVMQRVG 523
           + LY+        M    GW  P  +                        E+  V    G
Sbjct: 5   TPLYEQHTLCGARMVDFHGWMMPLHY-------------------GSQIDEHHAVRTDAG 45

Query: 524 VIDLSPFGKFNIKGQDSTQLLDHLCANVIPKV---GFTNISHMLTPRGRVYAELTVSHQS 580
           + D+S     +++G  + + L +L AN + K+   G    S ML   G V  +L V + +
Sbjct: 46  MFDVSHMTIVDLRGSRTREFLRYLLANDVAKLTKSGKALYSGMLNASGGVIDDLIVYYFT 105

Query: 581 PGEFLLITGSGSELHDLRWIEEAAVRGGYDVEIRNITDELGVLGVAGPYARRVLQKLTSE 640
              F L+  S +   DL WI + A   G ++ +R   D+L ++ V GP A+     L ++
Sbjct: 106 EDFFRLVVNSATREKDLSWITQHAEPFGIEITVR---DDLSMIAVQGPNAQAKAATLFND 162

Query: 641 DLSDDVFKFLQTKSLKISDIPVTAIRISYTGELGWELYHRREDSAALYERIMNAGQEEGI 700
                V        ++  D+ +      YTGE G+E+    E +A  +  ++ AG    +
Sbjct: 163 AQRQAVEGMKPFFGVQAGDLFIATT--GYTGEAGYEIALPNEKAADFWRALVEAG----V 216

Query: 701 DNFGTYALNALRLEKAFRAWGSEMNCDTNPLEAGLDYFIKLN-KPADFTGKQALKQIKAK 759
              G  A + LRLE     +G EM+   +PL A + + I       DF G++AL+  +  
Sbjct: 217 KPCGLGARDTLRLEAGMNLYGQEMDETISPLAANMGWTIAWEPADRDFIGREALEVQREH 276

Query: 760 GLKRRLVCLTLATDDV----------DPEGNESVWYKGKVIGNTTSGSYSYSIQKSLAFA 809
           G + +LV L +    V          D +GN+         G  TSG++S ++  S+A A
Sbjct: 277 GTE-KLVGLVMTEKGVLRNELPVRFTDAQGNQHE-------GIITSGTFSPTLGYSIALA 328

Query: 810 YVPVELSEVGQQVEVELLGKNYPATIIQEPLV 841
            VP     +G+   V++  +  P  + +   V
Sbjct: 329 RVP---EGIGETAIVQIRNREMPVKVTKPVFV 357


>2GAG-A nrPDB
          Length = 965

 Score =  333 bits (854), Expect = 2e-91,   Method: Composition-based stats.
 Identities = 100/408 (24%), Positives = 184/408 (45%), Gaps = 33/408 (8%)

Query: 463 RVSGLYK-ILESKCSMGFHAGWEQPHWFYKPGQDTQYRPSFRRTNWFRPVGSEYKQVMQR 521
           R++ ++   L           W++P W+Y    +T  +  +R          E K V   
Sbjct: 575 RITAMHSWHLSHGAEFEDVGQWKRP-WYYPQAGETMDQAVYR----------ESKAVRDS 623

Query: 522 VGVIDLSPFGKFNIKGQDSTQLLDHLCAN--VIPKVGFTNISHMLTPRGRVYAELTVSHQ 579
           VG++D +  GK  I+G+D+ + L+ +  N     KVG      M    G ++ +      
Sbjct: 624 VGMLDATTLGKIEIRGKDAAEFLNRIYTNGYTKLKVGMGRYGVMCKADGMIFDDGVTLRL 683

Query: 580 SPGEFLLITGSGSELHDLRWIEE--AAVRGGYDVEIRNITDELGVLGVAGPYARRVLQKL 637
           +   FLL T +G     L W+EE         DV   ++T++L  + V GP +R V+ KL
Sbjct: 684 AEDRFLLHTTTGGAADVLDWLEEWLQTEWPDLDVTCTSVTEQLATVAVVGPRSRDVIAKL 743

Query: 638 TSE-DLSDDVFKFLQTKSLKI-SDIPVTAIRISYTGELGWELYHRREDSAALYERIMNAG 695
            S  D+S++ FKF+  K + + S I     RIS++GEL +E+         ++E +  AG
Sbjct: 744 ASTVDVSNEGFKFMAFKDVVLDSGIEARISRISFSGELAFEIAVPAWHGLRVWEDVYAAG 803

Query: 696 QEEGIDNFGTYALNALRLEKAFRAWGSEMNCDTNPLEAGLDYFIKLNKPADFTGKQALKQ 755
           +E  I  +GT  ++ LR EK F   G + +    P +AG+++ +  +K  DF G ++  +
Sbjct: 804 EEFNITPYGTETMHVLRAEKGFIIVGQDTDGTVTPQDAGMEWVV--SKLKDFIGNRSYSR 861

Query: 756 I-KAKGLKRRLVCLTLATDDV-DPEGNESVWYKG-------KVIGNTTSGSYSYSIQKSL 806
              A+  +++LV +      +  PEG   V            + G  TS   S ++ ++ 
Sbjct: 862 ADNAREDRKQLVSVLPVDKSLRLPEGAALVASDALASEGITPMEGWVTSSYDSPNLGRTF 921

Query: 807 AFAYVPVELSEVGQQVEVELLGKNYPATIIQEPLVLTEPTRTRLQKDG 854
             A +    + +G+ ++  +  +     + +  L   +P  +R  +DG
Sbjct: 922 GLALIKNGRNRIGEVLKTPVGDQLVDVVVSETVLY--DPEGSR--RDG 965


>1ZOV-A nrPDB
          Length = 386

 Score =  331 bits (849), Expect = 6e-91,   Method: Composition-based stats.
 Identities = 77/391 (19%), Positives = 153/391 (39%), Gaps = 26/391 (6%)

Query: 43  AETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAG--LTTYFHPGINLKK 100
            + +++G G +G++  Y+LAK G++ +++          + H     +   +  G     
Sbjct: 4   FDVIVVGAGSMGMAAGYYLAKQGVKTLLVDSFDPPHTNGSHHGDTRIIRHAYGEGREYVP 63

Query: 101 IHYDSIKLYERLEEETGQVVGFHQPGSIRLATTPERVDEFKYQ-MTRTNWHATEQYIIEP 159
               + +L+  LE+ET   + F Q G   L   P+    F  + M   N H+ E  + E 
Sbjct: 64  FALRAQELWYELEKETHHKI-FTQTGV--LVYGPKGGSAFVSETMEAANIHSLEHELFEG 120

Query: 160 EKIHELFPLLNMDKILAGLYNPGDGHIDPYSLTMALATGARKYGVLLKYPAPVTSLKPRP 219
           +++ + +  + +      ++ P  G +   +   A    A  +G  +    PV   +   
Sbjct: 121 KQLTDRWAGVEVPDNYEAIFEPNSGVLFSENCIQAYRELAEAHGATVLTYTPVEDFEVTE 180

Query: 220 DGTWDVETPQGSVRANRIVNAAGFWAREVGKMIGLDHPLIPVQHQYVVTSTIPEVKALKR 279
           D    ++T +GS  AN++V + G W  ++   + ++ PL P + Q V      E K    
Sbjct: 181 D-LVTIKTAKGSYTANKLVVSMGAWNSKLLSKLDVEIPLQPYR-QVVGFFECDEAK---- 234

Query: 280 ELPVLRDLEGSYYLRQERDGLLFG-PYESQEKMKLQASWVAHGVPPGFGKE---LFESDL 335
                 +     ++ +  +G+ +G P      +K+        + P         +  D 
Sbjct: 235 ---YSNNAHYPAFMVEVENGIYYGFPSFGGSGLKIGYHSYGQQIDPDTINREFGAYPEDE 291

Query: 336 DRITEHVEAAMEMVP-VLKKADIINIVNGPITYSPDILPMVGPHQGVRNYWVAIGF-GYG 393
             + + +E  M      LKK  +        T +PD   ++  H    N  +A GF G+G
Sbjct: 292 ANLRKFLEQYMPGANGELKKGAVCM-----YTKTPDEHFVIDLHPKYSNVAIAAGFSGHG 346

Query: 394 IIHAGGVGKYLSDWILHGEPPFDLIELDPNR 424
              +  VG+ L+     G+   D+     NR
Sbjct: 347 FKFSSVVGETLAQLATTGKTEHDISIFSLNR 377


>1VRQ-A nrPDB
          Length = 964

 Score =  329 bits (844), Expect = 2e-90,   Method: Composition-based stats.
 Identities = 100/408 (24%), Positives = 184/408 (45%), Gaps = 33/408 (8%)

Query: 463 RVSGLYK-ILESKCSMGFHAGWEQPHWFYKPGQDTQYRPSFRRTNWFRPVGSEYKQVMQR 521
           R++ ++   L           W++P W+Y    ++     +R          E K V   
Sbjct: 574 RLTAMHPWHLAHGAKFEDVGQWKRP-WYYPQDGESMDEAVYR----------ECKAVRDS 622

Query: 522 VGVIDLSPFGKFNIKGQDSTQLLDHLCAN--VIPKVGFTNISHMLTPRGRVYAELTVSHQ 579
           VG++D S  GK  I+G+D+ + L+ +  N     KVG      M    G ++ +      
Sbjct: 623 VGMLDASTLGKIEIRGKDAAEFLNRMYTNGYTKLKVGMGRYGVMCKADGMIFDDGVTLRL 682

Query: 580 SPGEFLLITGSGSELHDLRWIEE--AAVRGGYDVEIRNITDELGVLGVAGPYARRVLQKL 637
           +   FL+ T +G     L W+EE         DV   ++T++L  + V GP +R V+ KL
Sbjct: 683 AEDRFLMHTTTGGAADVLDWLEEWLQTEWPELDVTCTSVTEQLATVAVVGPRSRDVIAKL 742

Query: 638 TSE-DLSDDVFKFLQTKSLKI-SDIPVTAIRISYTGELGWELYHRREDSAALYERIMNAG 695
            S  D+S+D FKF+  + + + S I     RIS++GEL +E+         ++E +  AG
Sbjct: 743 ASSLDVSNDAFKFMAFQDVTLDSGIEARISRISFSGELAFEIAIPAWHGLQVWEDVYAAG 802

Query: 696 QEEGIDNFGTYALNALRLEKAFRAWGSEMNCDTNPLEAGLDYFIKLNKPADFTGKQALKQ 755
           QE  I  +GT  ++ LR EK F   G + +    P +AG+++ +  +K  DF GK++  +
Sbjct: 803 QEFNITPYGTETMHVLRAEKGFIIVGQDTDGTVTPQDAGMEWVV--SKLKDFVGKRSFSR 860

Query: 756 I-KAKGLKRRLVCLTLAT------DDVDPEGNESVWYKG--KVIGNTTSGSYSYSIQKSL 806
               +  ++ LV +          +       ++V  +G   + G  T    S ++ ++ 
Sbjct: 861 EDNVREDRKHLVSVLPVDSSLRLAEGAALVAADAVASEGVTPMEGWVTHAYNSPALGRTF 920

Query: 807 AFAYVPVELSEVGQQVEVELLGKNYPATIIQEPLVLTEPTRTRLQKDG 854
             A +    + +G+ ++  + G+     +    LVL +P  +R  +DG
Sbjct: 921 GLALIKNGRNRIGEVLKTPVDGQLVDVQVSD--LVLFDPEGSR--RDG 964


>3TFJ-A nrPDB
          Length = 369

 Score =  329 bits (842), Expect = 4e-90,   Method: Composition-based stats.
 Identities = 63/339 (18%), Positives = 147/339 (43%), Gaps = 15/339 (4%)

Query: 508 FRPVGSEYKQVMQRVGVIDLSPFGKFNIKGQDSTQLLDHLCANVIPK--VGFTNISHMLT 565
           F  +   YK + + V + D++   +  I G+DS +L+  +    + K  +G      ++ 
Sbjct: 41  FGSIEDSYKHLKEHVQIWDVAAERQVEISGKDSAELVQLMTCRDLSKSKIGRCYYCPIID 100

Query: 566 PRGRVYAELTVSHQSPGEFLLITGSGSELHDLRWIEEAAVRGGYDVEIRNITDELGVLGV 625
             G +  +  V      ++ +       +   +      +  G+  +++ +   + ++ +
Sbjct: 101 ENGNLVNDPVVLKLDENKWWISIADSDVIFFAK-----GLASGHKFDVKIVEPVVDIMAI 155

Query: 626 AGPYARRVLQKLTSEDLSDDVFKFLQTKSLKISDIPVTAIRISYTGELGWELYHRRED-S 684
            GP +  +++K+  + +++   KF                R  ++ + G+E+Y       
Sbjct: 156 QGPKSFALMEKVFGKKITE--LKFFGFDYFDFEGTKHLIARSGWSKQGGYEVYVENTQSG 213

Query: 685 AALYERIMNAGQEEGIDNFGTYALNAL-RLEKAFRAWGSEMNCDTNPLEAGLDYFIKLNK 743
             LY+ +   G+E  +   G    N + R+E A  ++G++ + + NP E G D ++ L+ 
Sbjct: 214 QKLYDHLFEVGKEFNV---GPGCPNLIERIESALLSYGNDFDNNDNPFECGFDQYVSLDS 270

Query: 744 PADFTGKQALKQIKAKGLKRRLVCLTLATDDVDPEGNESVW-YKGKVIGNTTSGSYSYSI 802
             +F GK+ LK+IK KG +++L  + +   ++   G+++++     VIG   S  YS   
Sbjct: 271 DINFLGKEKLKEIKLKGPQKKLRGVKIDIKEISLTGSKNIYDENNNVIGELRSACYSPHF 330

Query: 803 QKSLAFAYVPVELSEVGQQVEVELLGKNYPATIIQEPLV 841
           QK +  A +     E  Q  ++++        +   P +
Sbjct: 331 QKVIGIAMIKKSHWEASQGFKIQINDNTINGNVCDLPFI 369


>1NG3-A nrPDB
          Length = 390

 Score =  302 bits (772), Expect = 6e-82,   Method: Composition-based stats.
 Identities = 91/386 (23%), Positives = 153/386 (39%), Gaps = 51/386 (13%)

Query: 59  YHLAKAGMRDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKIHYD----SIKLYERLEE 114
           Y+LAK   ++  L E   +   +T  AAG+    H     +   +D    S +LY+ L E
Sbjct: 42  YYLAKEN-KNTALFESGTMGGRTTSAAAGMLGA-HAECEERDAFFDFAMHSQRLYKGLGE 99

Query: 115 ETGQVVGF----HQPGSIRLATTPERVDEFKY--QMTRTNWHATEQYIIEPEKIHELFPL 168
           E   + G     H  G  +LA + E V + +    +   +W++        E++ E  P 
Sbjct: 100 ELYALSGVDIRQHNGGMFKLAFSEEDVLQLRQMDDLDSVSWYS-------KEEVLEKEPY 152

Query: 169 LNMDKILAGLYNPGDGHIDPYSLTMALATGARKYGVLLKYPAPVTSLKPRPDGTWDVETP 228
            + D I    +   D H++PY +  A    A+  G  +    PV  ++   +  + ++TP
Sbjct: 153 ASGD-IFGASFIQDDVHVEPYFVCKAYVKAAKMLGAEIFEHTPVLHVERDGEALF-IKTP 210

Query: 229 QGSVRANRIVNAAGFWAREVGKMIGLDHPLIPVQHQY--VVTSTIPEVKALKRELPVLRD 286
            G V AN +V A+G W+    K +GL++  +PV+ +   V    IP  K L  +      
Sbjct: 211 SGDVWANHVVVASGVWSGMFFKQLGLNNAFLPVKGECLSVWNDDIPLTKTLYHD------ 264

Query: 287 LEGSYYLRQERDGLLFGPYESQEKMKLQASWVAHGVPPGFGKELFESDLDRITEHVEAAM 346
                Y+   + G L                V   + PG   E    DL  +   ++ A 
Sbjct: 265 ---HCYIVPRKSGRLV---------------VGATMKPGDWSE--TPDLGGLESVMKKAK 304

Query: 347 EMVPVLKKADIINIVNGPITYSPDILPMVGPHQG-VRNYWVAIGFGYGIIHAGGVGKYLS 405
            M+P ++   +     G    + D  P +G H    R  + A  F  GI+ A   G  +S
Sbjct: 305 TMLPPIQNMKVDRFWAGLRPGTKDGKPYIGRHPEDSRILFAAGHFRNGILLAPATGALIS 364

Query: 406 DWILHGEPPFD-LIELDPNRYGKWTT 430
           D I++ E   D L     +R      
Sbjct: 365 DLIMNKEVNQDWLHAFRIDRKEAVQI 390


>3SM8-A nrPDB
          Length = 381

 Score =  292 bits (747), Expect = 5e-79,   Method: Composition-based stats.
 Identities = 95/395 (24%), Positives = 159/395 (40%), Gaps = 56/395 (14%)

Query: 43  AETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKIH 102
           A+ ++IG G  G S  Y L+  G R VVL  +++    ST  +A   T  +    ++ + 
Sbjct: 10  ADYLVIGAGIAGASTGYWLSAHG-RVVVLEREAQPGYHSTGRSAAHYTVAYGTPQVRALT 68

Query: 103 YDSIKLYERLEEETGQVVGFHQPGSIRLATTPERV-------DEFKYQMTRTNWHATEQY 155
             S   ++          GF +     L+  PE V       +E + Q         +  
Sbjct: 69  AASRAFFDN------PPAGFCE--HPLLSPRPEMVVDFSDDPEELRRQYESGKALVPQMR 120

Query: 156 IIEPEKIHELFPLLNMDKILAGLYNPGDGHIDPYSLTMALATGARKY--GVLLKYPAPVT 213
           +++ E+   + P+L  DK+    Y+P    ID  +L      G R+    VL  + A   
Sbjct: 121 LLDAEQACSIVPVLRRDKVFGATYDPTGADIDTDALHQGYLRGIRRNQGQVLCNHEALEI 180

Query: 214 SLKPRPDGTWDVETPQGSVRANRIVNAAGFWAREVGKMIGLD-HPLIPVQHQYVVTSTIP 272
               R DG W+V    GS RA  +VNAAG W   +  + G+    L P +    + +  P
Sbjct: 181 ---RRVDGAWEVRCDAGSYRAAVLVNAAGAWCDAIAGLAGVRPLGLQPKRRSAFIFAPPP 237

Query: 273 EVKALKRELPVLRDLEGSYYLRQERDGLLFGPYESQEKMKLQASWVAHGVPPGFGKELFE 332
            +     + P+L  L+ S+YL+ +  G+L G   + + ++      AH V P        
Sbjct: 238 GIDC--HDWPMLVSLDESFYLKPDA-GMLLGSPANADPVE------AHDVQP-------- 280

Query: 333 SDLDRITEHVEAAMEMVPVLKKADIINIVNGPITYSPDILPMVGPHQGVRNY-------- 384
                  E ++ A  M  ++++A  + I     T++  +   V     V  Y        
Sbjct: 281 -------EQLDIATGMY-LIEEATTLTIRRPEHTWA-GLRSFVADGDLVAGYAANAEGFF 331

Query: 385 WVAIGFGYGIIHAGGVGKYLSDWILHGEPPFDLIE 419
           WVA   GYGI  +  +G+  +  I H   P  L E
Sbjct: 332 WVAAQGGYGIQTSAAMGEASAALIRHQPLPAHLRE 366


>4YSH-A nrPDB
          Length = 376

 Score =  253 bits (645), Expect = 3e-67,   Method: Composition-based stats.
 Identities = 101/398 (25%), Positives = 169/398 (42%), Gaps = 46/398 (11%)

Query: 42  RAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAGLTTY---FHPGINL 98
           R +  I+GGG +G ++ + LAK   R V + EK  + +G++  AAG+      F     L
Sbjct: 4   RYDVAIVGGGVIGAAIGFELAKRRHR-VAIFEKGTMGSGASSAAAGMLGAQSEFSTSSPL 62

Query: 99  KKIHYDSIKL----YERLEEETGQVVGFHQPGSIRLATTPERVDEFKYQMTRTNWHATEQ 154
             +   S  L     E L E TG  +G  + G I+LATT E  D+     T   W    +
Sbjct: 63  VPLALQSRALMPALAEELRERTGIDIGLVEKGLIKLATTEEEADDLYRHYT--FWRGIGE 120

Query: 155 --YIIEPEKIHELFPLLNMDKILAGLYNPGDGHIDPYSLTMALATGARKYGVLLKYPAPV 212
               +   +  E+ P L  + +   +Y PGDG +    L  ALA  A   G  L     V
Sbjct: 121 PVQWLTKGEALEMEPRLA-EALAGAMYIPGDGQVSAPDLAAALAYAAASAGACLYEYTEV 179

Query: 213 TSLKPRPDGTWDVETPQGSVRANRIVNAAGFWAREVGKMIGLDHPLIPVQHQYVVTSTIP 272
             ++    G   ++T  G+  A  +V A+G WA  +G  +GL   + PV+ + V+     
Sbjct: 180 FDIRSDSSGHV-LDTTGGTFAAEAVVIASGAWAARLGARVGLSLSVYPVKGECVM----- 233

Query: 273 EVKALKRELPVLRDL----EGSYYLRQERDGLLFGPYESQEKMKLQASWVAHGVPPGFGK 328
               ++  +P+L+       G Y + +  + LL G               A   P  F +
Sbjct: 234 ----VRAPVPLLQTTVFAKNGCYIVPKSGNRLLIG---------------ATSTPGTFDR 274

Query: 329 ELFESDLDRITEHVEAAMEMVPVLKKADIINIVNGPITYSPDILPMVGPHQGVRNYWVAI 388
            +    +  +   +  A  +VP +++A+ +   +G    + D LP +G H   R  +VA 
Sbjct: 275 RVSAGGVMNL---LHRAAHLVPDIEQAEWVASWSGIRPQTEDGLPYLGEHPERRGLFVAA 331

Query: 389 G-FGYGIIHAGGVGKYLSDWILHGEPPFDLIELDPNRY 425
           G +  GI+ +   G  ++D +   E  FDL      R+
Sbjct: 332 GHYRNGILLSPLTGLLVADLVERKETAFDLAPFSLTRH 369


>2UZZ-A nrPDB
          Length = 372

 Score =  186 bits (472), Expect = 3e-47,   Method: Composition-based stats.
 Identities = 59/389 (15%), Positives = 130/389 (33%), Gaps = 22/389 (5%)

Query: 42  RAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAG--LTTYFHPGINLK 99
           + + +IIG G VG +  Y+  +AG+  ++           + H     +   +  G    
Sbjct: 2   KYDLIIIGSGSVGAAAGYYATRAGLNVLMTDAHMPPHQHGSHHGDTRLIRHAYGEGEKYV 61

Query: 100 KIHYDSIKLYERLEEETGQVVGFHQPGSIRLATTPERVDEFKYQMTRTNWHATEQYIIEP 159
            +   +  L++ L         F + G I L                          ++ 
Sbjct: 62  PLVLRAQMLWDELSRHNEDDPIFVRSGVINLGPADSTFLANVAH--SAEQWQLNVEKLDA 119

Query: 160 EKIHELFPLLNMDKILAGLYNPGDGHIDPYSLTMALATGARKYGVLLKYPAPVTSLKPRP 219
           + I   +P + +     GL+    G +            A++ G    +  PVT+++   
Sbjct: 120 QGIMARWPEIRVPDNYIGLFETDSGFLRSELAIKTWIQLAKEAGCAQLFNCPVTAIRHDD 179

Query: 220 DGTWDVETPQGSVRANRIVNAAGFWAREVGKMIGLDHPLIPVQHQYVVTSTIPEVKALKR 279
           DG   +ET  G  +A + +  AG W +++      + P+ PV+  +            + 
Sbjct: 180 DGVT-IETADGEYQAKKAIVCAGTWVKDLLP----ELPVQPVRKVFAWY---------QA 225

Query: 280 ELPVLRDLEGSYYLRQERDG-LLFGPYESQEKMKLQASWVAHGVPPGFGKELFESDLDRI 338
           +       +   +  +  +G   +G     + +K+        +     +  F   +   
Sbjct: 226 DGRYSVKNKFPAFTGELPNGDQYYGFPAENDALKIGKHNGGQVIHSADERVPFAEVVSDG 285

Query: 339 TEHVEAAMEMVPVLKKADIINIVNGPITYSPDILPMVGPHQGVRN-YWVAIGFGYGIIHA 397
           +E       ++P +     +         SPD   ++    G  N   +    G+G   A
Sbjct: 286 SEAFPFLRNVLPGI--GCCLYGAACTYDNSPDEDFIIDTLPGHDNTLLITGLSGHGFKFA 343

Query: 398 GGVGKYLSDWILHGEPPFDLIELDPNRYG 426
             +G+  +D+    +  FDL     +R+ 
Sbjct: 344 SVLGEIAADFAQDKKSDFDLTPFRLSRFQ 372


>5X1I-A nrPDB
          Length = 474

 Score =  109 bits (272), Expect = 6e-24,   Method: Composition-based stats.
 Identities = 79/394 (20%), Positives = 139/394 (35%), Gaps = 87/394 (22%)

Query: 508 FRPVGSEYKQVMQRVGVIDLSP-FGKFNIKGQDSTQLLDHLCANVIP--KVGFTNISHML 564
           F    +E         + D +       I+G+D+ +LL     N     +         +
Sbjct: 41  FSNWRTEQWAWRNSAVLFDQTHHMVDLYIRGKDALKLLSDTMINSPKGWEPNKAKQYVPV 100

Query: 565 TPRGRVYAELTVSHQSPGEFLLITGSGSELHDLRWIEEAAVRGGYDVEI--RNITDELGV 622
           TP G V  +  + + +  EF+ +           W+   A  GGY+V+I   + +    +
Sbjct: 101 TPYGHVIGDGIIFYLAEEEFVYV----GRAPAANWLMYHAQTGGYNVDIVHDDRSPSRPM 156

Query: 623 ----------LGVAGPYARRVLQKLTSEDLSDDVFKFLQTKSLKISDIPVTAIRISYTGE 672
                       + GP A  V++KL    L  +  KF     + I+ + +  +R    G 
Sbjct: 157 GKPVQRISWRFQIQGPKAWDVIEKLHGGTL--EKLKFFNMAEMNIAGMKIRTLRHGMAGA 214

Query: 673 LGWELYHRREDSAALYERIMNAGQEEGIDNFGTYALNALRLEKA---------------- 716
            G E++   E        I+ AG+E G+   G+ A  +  LE                  
Sbjct: 215 PGLEIWGPYETQEKARNAILEAGKEFGLIPVGSRAYPSNTLESGWIPSPLPAIYTGDKLK 274

Query: 717 -FRAW-------------GSEMNCDT-----NPLEAGLDYFIKLNKPADFTGKQALKQIK 757
            +R W             GS ++ +      NP E G   F+K +   DF G+ AL+ I 
Sbjct: 275 AYREWLPANSYEASGAIGGSFVSSNIEDYYVNPYEIGYGPFVKFDH--DFIGRDALEAI- 331

Query: 758 AKGLKRRLVCLTLATDDVDPEGNESVWYK---------------------------GKVI 790
               +R+ V L    DD+          +                           G V+
Sbjct: 332 DPATQRKKVTLAWNGDDMAKIYASLFDTEADAHYKFFDLPLANYANTNADAVLDAAGNVV 391

Query: 791 GNTTSGSYSYSIQKSLAFAYVPVELSEVGQQVEV 824
           G +    YSY+ +++L+ A +  E+  VG ++ V
Sbjct: 392 GMSMFTGYSYNEKRALSLATIDHEIP-VGTELTV 424


>5XAO-A nrPDB
          Length = 445

 Score = 94.5 bits (233), Expect = 2e-19,   Method: Composition-based stats.
 Identities = 66/382 (17%), Positives = 135/382 (35%), Gaps = 28/382 (7%)

Query: 58  AYHLAKAGMR--DVVLLEKSELTAGSTWHA--AGLTTYFHPGINLKKIHYDSIKLYERLE 113
           A HL ++G    +V +L+   + +  +     A +           ++  ++ +++    
Sbjct: 24  ALHLVRSGYTPSNVTVLDAYPIPSSQSAGNDLAKIMGVSLRNPVDLQLALEARQMW---N 80

Query: 114 EETGQVVGFHQPGSIRLATTPERVDEFKYQMTR---TNWHATEQYIIEPEKIHELFPLLN 170
           E+      FH  G +  A   + + + K            AT +++   ++I +  PLL+
Sbjct: 81  EDELFKKFFHNTGRLDCAHGEKDIADLKSGYQALVDAGLDATNEWLDSEDEILKRMPLLS 140

Query: 171 MDKILA--GLYNPGDGHIDPYSLTMALATGARKYGVLL-KYPAPVTSLKPRPDGT-WDVE 226
            D+I     +++   G +       A+    R  GV    Y A         +G    VE
Sbjct: 141 RDQIKGWKAIFSKDGGWLAAAKAINAVGEYLRDQGVRFGFYGAGSFKAPLLAEGVCIGVE 200

Query: 227 TPQGS-VRANRIVNAAGFWAREVGKMIGLDHPLIPVQHQYVVTSTIPEVKALKRELPVLR 285
           T  G+   A+++V AAG W+  + +   L    +     Y      PE  A  +  PV+ 
Sbjct: 201 TVDGTRYYADKVVLAAGAWSPTLVE---LHEQCVSKAWVYGHIQLTPEEAARYKNSPVVY 257

Query: 286 DLEGSYYLRQERDGLL-FGPYESQEKMKLQASWVAHGVPPGFG--KELFESDLDRITEHV 342
           + +  ++      G++                      P      +   +   D I +  
Sbjct: 258 NGDVGFFFEPNEHGVIKVCDEFPGFTRFKMHQPFGAKAPKRISVPRSHAKHPTDTIPDAS 317

Query: 343 E-----AAMEMVPVLKKADIINIVNGPITYSPDILPMVGPHQGVRNYWVAIG-FGYGIIH 396
           +     A    +P  K   + N      T + D   ++  H   +N+ +A G  G+    
Sbjct: 318 DVSIRRAIATFMPQFKNKKMFNQAMCWCTDTADAALLICEHPEWKNFVLATGDSGHSFKL 377

Query: 397 AGGVGKYLSDWILHGEPPFDLI 418
              +GK++ + +  G    DL 
Sbjct: 378 LPNIGKHVVELLE-GTLADDLA 398


>3VQR-A nrPDB
          Length = 447

 Score = 81.0 bits (198), Expect = 2e-15,   Method: Composition-based stats.
 Identities = 66/403 (16%), Positives = 139/403 (34%), Gaps = 36/403 (8%)

Query: 42  RAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKS-ELTAGSTWHAAGLTTYFHPGINLKK 100
           R + V++G G VG++ AY+L       V++++      +G +  +      F      + 
Sbjct: 23  RFDYVVVGAGVVGLAAAYYLKVWSGGSVLVVDAGHAPGSGDSGRSMAAFRTFFSSTMNRL 82

Query: 101 IHYDSIKLYERLEEETGQVVGFHQPGSIRLATTPERVDEFKYQMTRTNWHATEQYIIEPE 160
           +   +++L+E   +  G+ +G  + G +      ER  E +  +        +  II PE
Sbjct: 83  VAGSTVRLFED-AQRGGEDLGLVKSGYL-FVYDRERWREVEEPLREAGEEGRDYLIIPPE 140

Query: 161 KIH------------ELFPLLNMDKILAGLYNPGDGHIDPYSLTMALATGARKYGVLLKY 208
           ++             E   +L +  +   +     G +D   +       A   GV   +
Sbjct: 141 ELERRLGMNTRVSDGEEAEVLGVGDVEGAVLIRSAGFLDAEKVVDYYYRRASGAGVEFIF 200

Query: 209 PAPVTSLKPRPDGTWDVE---------TPQGSVRAN--------RIVNAAGFWAREVGKM 251
              V  ++ +P     +E             +V ++        ++V AAG W+  +   
Sbjct: 201 GRRVVGVELKPRVELGIEGEPLPWQEARASAAVLSDGTRVEVGEKLVVAAGVWSNRLLNP 260

Query: 252 IGLDHPLIPVQHQYV-VTSTIPEVKALKRELPVLRDLEGSYYLRQERDGLLFGPYESQEK 310
           +G+D    P +     V+++   ++ + RE  +         +      +L  P   +  
Sbjct: 261 LGIDTFSRPKKRMVFRVSASTEGLRRIMREGDLAGAGAPPLIILP--KRVLVRPAPREGS 318

Query: 311 MKLQASWVAHGVPPGFGKELFESDLDRITEHVEAAMEMVPVLKKADIINIVNGPITYSPD 370
             +Q S    G P    ++    +       +      +P  + A       G    S D
Sbjct: 319 FWVQLSD-NLGRPFALEEDPQPEEHYYSLAILPILSLYLPQFQDAYPSGGWAGHYDISFD 377

Query: 371 ILPMVGPHQGVRNYWVAIGFGYGIIHAGGVGKYLSDWILHGEP 413
             P+V           A   G GI+ +  +G+  +   L  E 
Sbjct: 378 ANPVVFEPWESGIVVAAGTSGSGIMKSDSIGRVAAAVALGMES 420


>3PVC-A nrPDB
          Length = 689

 Score = 55.6 bits (132), Expect = 8e-08,   Method: Composition-based stats.
 Identities = 94/466 (20%), Positives = 148/466 (31%), Gaps = 92/466 (19%)

Query: 18  QGRPSSAGLREGQESPPSPPEWKDRA-----ETVIIGGGCVGVSLAYHLAKAGMRDVVLL 72
           Q R    G    Q   P+ P +   A     +  IIGGG V    A  L + G    +  
Sbjct: 235 QKREMLTGTLPQQIHAPTAPWYHRPAATRCDDIAIIGGGIVSALTALALQRRGAVVTLYC 294

Query: 73  EKSELTAGSTWHAAGLTTYFHPGINLK------KIHYDSIKLYERLEEETGQVVGFHQPG 126
             ++   G++ +  G       G N             + + Y++L E+ G        G
Sbjct: 295 ADAQPAQGASGNRQGALYPLLNGKNDALETFFTSAFTFARRQYDQLLEQ-GIAFDHQWCG 353

Query: 127 SIRLATTPERVDEFKYQMTRTNWHATEQYIIEPEKIHELFPLLNMDKILAGLYNPGDGHI 186
             +LA   +       +M  T W       +  E++ EL     +D    G++ P  G +
Sbjct: 354 VSQLAFDDKS-RGKIEKMLHTQWPVEFAEAMSREQLSEL---AGLDCAHDGIHYPAGGWL 409

Query: 187 DPYSLTMALATGARKYGVLLKYPAPVTSLKPRPDGTWDVETPQGSVRANR---IVNAAGF 243
            P  LT AL   A++ G+   Y   +  LK R D  W + T   S  A     ++ A G 
Sbjct: 410 CPSDLTHALMMLAQQNGMTCHYQHELQRLK-RIDSQWQL-TFGQSQAAKHHATVILATGH 467

Query: 244 ----WAREVGKMIGLDHPLIPVQHQYVVTSTIPEVKALKRELPVLRDLEGSYYLRQERDG 299
               W +          PL  V+ Q     T P +  L++ L          YL      
Sbjct: 468 RLPEWEQT------HHLPLSAVRGQVSHIPTTPVLSQLQQVLCY------DGYLTPV--- 512

Query: 300 LLFGPYESQEKMKLQASWVAHGVPPGFGKELFESDLDRITEHVEAAMEMVPVL---KKAD 356
                         Q   +      G     F   L    E+ E  +  +P +   ++ D
Sbjct: 513 ----------NPANQHHCIGASYQRGDIATDFR--LTEQQENRERLLRCLPQVSWPQQVD 560

Query: 357 IIN--IVNGPITYSPDILPMVGPHQGVRN------------------------------- 383
           + +     G      D LPMVG                                      
Sbjct: 561 VSDNQARCGVRCAIRDHLPMVGAVPDYAATLAQYQDLSRRIQHGGESEVNDIAVAPVWPE 620

Query: 384 YWVAIGFGY-GIIHAGGVGKYLSDWILHGEPPFD---LIELDPNRY 425
            ++  G G  G+  A  V + L+  +     P D   L  L+PNR+
Sbjct: 621 LFMVGGLGSRGLCSAPLVAEILAAQMFGEPLPLDAKTLAALNPNRF 666


>3PS9-A nrPDB
          Length = 676

 Score = 55.6 bits (132), Expect = 8e-08,   Method: Composition-based stats.
 Identities = 73/457 (15%), Positives = 131/457 (28%), Gaps = 70/457 (15%)

Query: 11  GLALRSSQG----RPSSAGLREGQESPPSPPEWKDRA-----ETVIIGGGCVGVSLAYHL 61
           G  ++  +G    R    G+ E     P    W +R      E  IIGGG     L+  L
Sbjct: 232 GFTMQKRKGFGRKREMLCGVMEQTLPLPCSAPWFNRTGSSKREAAIIGGGIASALLSLAL 291

Query: 62  AKAGMRDVV-LLEKSELTAGSTWHAAGLTTYFHPGIN-----LKKIHYDSIKLYERLEEE 115
            + G +  +   +++     S      L                     + + Y++L  +
Sbjct: 292 LRRGWQVTLYCADEAPALGASGNRQGALYPLLSKHDEALNRFFSNAFTFARRFYDQLPVK 351

Query: 116 TGQVVGFHQPGSIRLATTPERVDEFKYQMTRTNWHATEQYIIEPEKIHELFPLLNMDKIL 175
                     G  +L    +   +    ++          +    + + +  +  +    
Sbjct: 352 FDHDWC----GVTQLGWDEKSQHKIAQMLSMD----LPAELAVAVEANAVEQITGVATNC 403

Query: 176 AGLYNPGDGHIDPYSLTMALATGARKYGVLLKYPAPVTSLKPRPDGTWDVETPQGSVRAN 235
           +G+  P  G + P  LT  +   A++ G+ + Y   + +   R D  W +         +
Sbjct: 404 SGITYPQGGWLCPAELTRNVLELAQQQGLQIYYQYQLQNF-SRKDDCWLLNFAGDQQATH 462

Query: 236 RIVNAAGFWAREVGKMIGLDHPLIPVQHQYVVTSTIPEVKALKRELPVLRDLEGSYYLRQ 295
            +V  A               P+  V  Q     T PE+  LK+ L          YL  
Sbjct: 463 SVVVLANGHQISRFSQTS-TLPVYSVAGQVSHIPTTPELAELKQVLCY------DGYLTP 515

Query: 296 ERDGLLFGPYESQEKMKLQASWVAHGVP-PGFGKELFESDLDRITEHVEAAMEMVPVLKK 354
           +       P      +       +         ++     L       + A E+    K+
Sbjct: 516 Q------NPANQHHCIGASYHRGSEDTAYSEDDQQQNRQRLIDCFPQAQWAKEVDVSDKE 569

Query: 355 ADIINIVNGPITYSPDILPMVGPHQGVRNYWV------------------------AIGF 390
           A       G    + D LPMVG         V                        A   
Sbjct: 570 A-----RCGVRCATRDHLPMVGNVPDYEATLVEYASLAEQKDEAVSAPVFDDLFMFAALG 624

Query: 391 GYGIIHAGGVGKYLSDWILHGEPPFD---LIELDPNR 424
             G+  A    + L+  +     P D   L  L+PNR
Sbjct: 625 SRGLCSAPLCAEILAAQMSDEPIPMDASTLAALNPNR 661


>5EZ7-A nrPDB
          Length = 392

 Score = 54.1 bits (128), Expect = 3e-07,   Method: Composition-based stats.
 Identities = 43/263 (16%), Positives = 77/263 (29%), Gaps = 32/263 (12%)

Query: 42  RAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKI 101
             + +I+GGG  G+ L   L +AG   V++ E + L  G +  + G+            +
Sbjct: 7   STDILIVGGGIAGLWLNARLRRAGYATVLV-ESASLGGGQSVKSQGIIHGGAKYALHGAL 65

Query: 102 HYDSIKLYE---RLEEETGQVVGFHQPGSIRLA-----TTPERVDEFKYQMTRTNWHATE 153
              S  + +   R     G        G   L+      +P  +         +    + 
Sbjct: 66  TGASEAIADMPRRWRACLGSDGELDLRGVRLLSEAHYLWSPGGLAGSLTSFFASKAVRSR 125

Query: 154 QYIIEPEKIHELFPLLNMDKILAGLYNPGDGHIDPYSLTMALATGARKYGVLLKYPAPVT 213
               + E   +L P L         Y   +   D   L       A   G  L     + 
Sbjct: 126 VEQAKGE---DLPPALRDKGFKGKAYRLTEIVFDVPDLI---RRLAELAGDSLLAGERIE 179

Query: 214 SLKPRPDGTWDVETPQGSVRANRIVNAAGFWAREVGKMIGLDHP---------------- 257
            L         +      +RA R+V +AG     + + +GL+ P                
Sbjct: 180 PL-REGRELAGLCVDGREIRAQRVVLSAGAGNEALLRELGLEQPAMQRRPLHMVMVKAAT 238

Query: 258 LIPVQHQYVVTSTIPEVKALKRE 280
           L P+    +     P +      
Sbjct: 239 LKPLYAHCLGAGPKPRITVTTHP 261


>5KOX-A nrPDB
          Length = 476

 Score = 54.1 bits (128), Expect = 3e-07,   Method: Composition-based stats.
 Identities = 47/262 (17%), Positives = 83/262 (31%), Gaps = 56/262 (21%)

Query: 44  ETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKIHY 103
           + +I GGG  G+ LA  L   G+R VVL ++      S                 + +H 
Sbjct: 6   DVIIAGGGPTGLMLAGELRLHGVRTVVLEKEPTPNQHS---------------RSRGLHA 50

Query: 104 DSIKLYERLEEETGQVVGFHQPGSIR--LATTPERVDEFKYQMTRTNWHATEQYIIEPEK 161
            SI++ +             Q G +   LA       +F+       +         P  
Sbjct: 51  RSIEVMD-------------QRGLLERFLAHGE----QFR---VGGFFAGLAAEW--PAD 88

Query: 162 IHELFPLLNMDKILAGLYNPGDGHIDPYSLTMALATGARKYGVLLKYPAPVTSLKPRPDG 221
           +      +        L  P    +    L   L   A + G  ++    V  L    DG
Sbjct: 89  LDTAHSYV--------LAIP---QVVTERL---LTEHATELGAEIRRGCEVAGLDQDADG 134

Query: 222 TWDVETPQGSVRANRIVNAAGFWAREVGKMIGLDHPLIPVQHQYVVTS--TIPEVKALKR 279
                     +RA  +V   G     V +++G+D P  P + + ++        V+ L  
Sbjct: 135 VTAELADGTRLRARYLVGCDGG-RSTVRRLLGVDFPGEPTRVETLLADVRIDVPVETLTA 193

Query: 280 ELPVLRDLEGSYYLRQERDGLL 301
            +  +R  +  +      DG  
Sbjct: 194 VVAEVRKTQLRFGAVPAGDGFF 215


>3ATQ-A nrPDB
          Length = 453

 Score = 52.1 bits (123), Expect = 1e-06,   Method: Composition-based stats.
 Identities = 67/407 (16%), Positives = 124/407 (30%), Gaps = 82/407 (20%)

Query: 42  RAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKI 101
           + + +IIGGG  G S AY L++ G++ +++  K                    G  + K 
Sbjct: 6   KYDVLIIGGGFAGSSAAYQLSRRGLKILLVDSKPW----------NRIGDKPCGDAVSKA 55

Query: 102 HYDSIKLYERLEEETGQVVGFHQPGSIRLATTPERVDEFKYQMTRTNWHATEQYIIEPEK 161
           H+D + +     EE    +       I+L  +P+                   + +  E 
Sbjct: 56  HFDKLGMPYPKGEELENKI-----NGIKL-YSPDM---------------QTVWTVNGEG 94

Query: 162 IHELFPLLNMDKILAGLYNPGDGHIDPYSLTMALATGARKYGVLLKYPAPV-----TSLK 216
                PL N                        +   A+  GV +               
Sbjct: 95  FELNAPLYN----------------------QRVLKEAQDRGVEIWDLTTAMKPIFEDGY 132

Query: 217 PRPDGTWDVETPQGSVRANRIVNAAGFWAREVGKMIGLDHPLIPVQHQYVVTSTIPEVKA 276
            +    ++  T +     +++V  A  ++R     +  + P+         T  + +  A
Sbjct: 133 VKGAVLFNRRTNEELTVYSKVVVEATGYSRSFRSKLPPELPI---------TEDLDDKDA 183

Query: 277 LKRELPVL---RDLEGSYYLRQERDGLLF-GPYESQEKMKLQASWVAHGVPPGFG----K 328
                 VL    D+E   YLR   D     G Y            V  G+  G G     
Sbjct: 184 DVAYREVLLTKEDIEDHDYLRIFIDQETSPGGYWWYFPKGKNKVNVGLGIQGGMGYPSIH 243

Query: 329 ELFESDLDRITEHVEAAMEMVPVLKKADIINIVNGPITYSPDILPMVGPHQGVRNYWVAI 388
           E ++  LD+    V+ +  +V   K   ++       T + + + ++G      N     
Sbjct: 244 EYYKKYLDKYAPDVDKSKLLV---KGGALVPTRRPLYTMAWNGIIVIGDSGFTVNPVHGG 300

Query: 389 GFGYGIIHAGGVGKYLSDWILHGEPPF----DLIELDPNRYGKWTTT 431
           G G  +I      K +      G+       D+     N YG    +
Sbjct: 301 GKGSAMISGYCAAKAILSAFETGDFSASGLWDMNICYVNEYGAKQAS 347


>1QO8-A nrPDB
          Length = 566

 Score = 51.0 bits (120), Expect = 2e-06,   Method: Composition-based stats.
 Identities = 32/214 (14%), Positives = 71/214 (33%), Gaps = 26/214 (12%)

Query: 39  WKDRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAGLTTYFHPGINL 98
             +  + +++G G  G + +    KAG  +V+L++K+  + G++  +AG           
Sbjct: 118 PSETTQVLVVGAGSAGFNASLAAKKAGA-NVILVDKAPFSGGNSMISAGGMNAVGTKQQT 176

Query: 99  KKIHYDSIKLYERLEEETGQVVGFHQPGSIRLATTP-ERVDEFKYQMTRTNWHATEQYII 157
                D ++ +         + G  Q   I+L T   E+  +    +     +  +    
Sbjct: 177 AHGVEDKVEWFIE-----DAMKGGRQQNDIKLVTILAEQSADGVQWLESLGANLDDLKRS 231

Query: 158 EPEKIHELFPLLNMDKILAGLYNPGDGHIDPYSLTMALATGARKYGVLLKYPAPVTSLKP 217
              ++                + P  G      +   L   A++ G+  +  + V  L  
Sbjct: 232 GGARVDR-------------THRPHGGKSSGPEIIDTLRKAAKEQGIDTRLNSRVVKLVV 278

Query: 218 RPDGTW------DVETPQGSVRANRIVNAAGFWA 245
             D +          T    + A  +V A G + 
Sbjct: 279 NDDHSVVGAVVHGKHTGYYMIGAKSVVLATGGYG 312


>3CUK-A nrPDB
          Length = 347

 Score = 50.2 bits (118), Expect = 3e-06,   Method: Composition-based stats.
 Identities = 64/393 (16%), Positives = 114/393 (29%), Gaps = 68/393 (17%)

Query: 45  TVIIGGGCVGVSLA------YHLAKAGMRDVVLLEKSELTAGSTWHAAGLTTYFHPGINL 98
            V+IG G +G+S A      YH     +   V  ++      +T  AAGL   +    N 
Sbjct: 3   VVVIGAGVIGLSTALCIHERYHSVLQPLDIKVYADRFTPLT-TTDVAAGLWQPYLSDPNN 61

Query: 99  KKIHYDSIKLYERLEEETGQVVGFHQPGSIRLATTPERVDEFKYQMTRTNWH--ATEQYI 156
            +    S + ++ L             G   ++      + F   +   +W         
Sbjct: 62  PQEADWSQQTFDYLLSHVHSPNA-ENLGLFLIS----GYNLFHEAIPDPSWKDTVLGFRK 116

Query: 157 IEPEKIHELFPLLNMDKILAGLYNPGDGHIDPYSLTMALATGARKYGVLLKYPAPVTSLK 216
           + P ++ ++FP           +      ++  +    L     + GV        +  +
Sbjct: 117 LTPREL-DMFP------DYGYGWFHTSLILEGKNYLQWLTERLTERGVKFFQRKVESFEE 169

Query: 217 PRPDGTWDVETPQGSVRANRIVNAAGFWAREVGKMIGLDHPLIPVQHQYVVTSTIPEVKA 276
              +G            A+ IVN  G WA  + +    D  L P + Q ++    P +K 
Sbjct: 170 VAREG------------ADVIVNCTGVWAGALQR----DPLLQPGRGQ-IMKVDAPWMK- 211

Query: 277 LKRELPVLRDLEGSYYLRQERDGLLFGPYESQEKMKLQASWVAHGVPPGFGKELFESDLD 336
                         + L  + +  ++           Q   +      G   EL      
Sbjct: 212 -------------HFILTHDPERGIYNSPYIIPG--TQTVTLGGIFQLGNWSELNNIQDH 256

Query: 337 RITEHVEAAMEMVPVLKKADII---NIVNGPITYSPDILPMVGPHQ---------GVRNY 384
                 E    + P LK A II                   +             G   Y
Sbjct: 257 NTI--WEGCCRLEPTLKNARIIGERTGFRPVRPQIRLEREQLRTGPSNTEVIHNYGHGGY 314

Query: 385 WVAIGFGYGIIHAGGVGKYLSDWILHGEPPFDL 417
            + I +G  +  A   G+ L +  L   PP  L
Sbjct: 315 GLTIHWGCALEAAKLFGRILEEKKLSRMPPSHL 347


>2RGO-A nrPDB
          Length = 607

 Score = 49.8 bits (117), Expect = 5e-06,   Method: Composition-based stats.
 Identities = 49/331 (14%), Positives = 95/331 (28%), Gaps = 53/331 (16%)

Query: 65  GMRDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKIHYDSIKLYERLEEET---GQVVG 121
           G++  ++ E  +   G++  +  L    H GI   K  +D   + + + E     G    
Sbjct: 41  GIKTGLI-EMQDFAEGTSSRSTKLV---HGGIRYLK-TFDVEVVADTVGERAVVQGIAPH 95

Query: 122 FHQPGSIRLATTPERVD------------EFKYQMTRTNWHATEQYIIEPEKIHELFPLL 169
             +P  + L    +               +   ++        E Y + PE++ E  P L
Sbjct: 96  IPKPDPMLLPIYEDEGATTFNMFSVKVAMDLYDKLANVTGTKYENYTLTPEEVLEREPFL 155

Query: 170 NMDKILAG----LYNPGDGHIDPYSLTMALATGARKYGVLLKYPAPVTSLKPRPDGTWDV 225
             + +        +   D  +   ++       A + G  L             D    V
Sbjct: 156 KKEGLKGAGVYLDFRNNDARLVIDNI-----KKAAEDGAYLVSKMKAVGFLYEGDQIVGV 210

Query: 226 ETPQG------SVRANRIVNAAGFWAREVGKMIGLDHPLIPVQHQYVVTSTIPEVKALKR 279
           +           ++A  ++N +G W  +V + +    P+ P          + + K L  
Sbjct: 211 KARDLLTDEVIEIKAKLVINTSGPWVDKV-RNLNFTRPVSPKMRPTKGIHLVVDAKKLPV 269

Query: 280 ELPVLRDLEGS----YYLRQERDGLLFGPYESQEKMKLQASWVAHGVPPGFGKELFESDL 335
             P   D         +     +   FG             +      P   +E  +  L
Sbjct: 270 PQPTYFDTGKQDGRMVFAIPRENKTYFGT--------TDTDYQGDFTDPKVTQEDVDYLL 321

Query: 336 DRITEHVEAAMEMVPVLKKADIINIVNGPIT 366
           D I      A      +  ADI     G   
Sbjct: 322 DVINHRYPEAN-----ITLADIEASWAGLRP 347


>2RGH-A nrPDB
          Length = 571

 Score = 49.8 bits (117), Expect = 6e-06,   Method: Composition-based stats.
 Identities = 49/331 (14%), Positives = 95/331 (28%), Gaps = 53/331 (16%)

Query: 65  GMRDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKIHYDSIKLYERLEEET---GQVVG 121
           G++  ++ E  +   G++  +  L    H GI   K  +D   + + + E     G    
Sbjct: 55  GIKTGLI-EMQDFAEGTSSRSTKLV---HGGIRYLK-TFDVEVVADTVGERAVVQGIAPH 109

Query: 122 FHQPGSIRLATTPERVD------------EFKYQMTRTNWHATEQYIIEPEKIHELFPLL 169
             +P  + L    +               +   ++        E Y + PE++ E  P L
Sbjct: 110 IPKPDPMLLPIYEDEGATTFNMFSVKVAMDLYDKLANVTGTKYENYTLTPEEVLEREPFL 169

Query: 170 NMDKILAG----LYNPGDGHIDPYSLTMALATGARKYGVLLKYPAPVTSLKPRPDGTWDV 225
             + +        +   D  +   ++       A + G  L             D    V
Sbjct: 170 KKEGLKGAGVYLDFRNNDARLVIDNI-----KKAAEDGAYLVSKMKAVGFLYEGDQIVGV 224

Query: 226 ETPQG------SVRANRIVNAAGFWAREVGKMIGLDHPLIPVQHQYVVTSTIPEVKALKR 279
           +           ++A  ++N +G W  +V + +    P+ P          + + K L  
Sbjct: 225 KARDLLTDEVIEIKAKLVINTSGPWVDKV-RNLNFTRPVSPKMRPTKGIHLVVDAKKLPV 283

Query: 280 ELPVLRDLEGS----YYLRQERDGLLFGPYESQEKMKLQASWVAHGVPPGFGKELFESDL 335
             P   D         +     +   FG             +      P   +E  +  L
Sbjct: 284 PQPTYFDTGKQDGRMVFAIPRENKTYFGT--------TDTDYQGDFTDPKVTQEDVDYLL 335

Query: 336 DRITEHVEAAMEMVPVLKKADIINIVNGPIT 366
           D I      A      +  ADI     G   
Sbjct: 336 DVINHRYPEAN-----ITLADIEASWAGLRP 361


>1KNR-A nrPDB
          Length = 540

 Score = 49.4 bits (116), Expect = 7e-06,   Method: Composition-based stats.
 Identities = 80/551 (14%), Positives = 151/551 (27%), Gaps = 115/551 (20%)

Query: 39  WKDRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAGLTTYFHPGINL 98
            +   + +IIG G  G+SLA  LA      V++L K  +T GST         F+    +
Sbjct: 5   PEHSCDVLIIGSGAAGLSLALRLADQ--HQVIVLSKGPVTEGST---------FYAQGGI 53

Query: 99  KKIHYDSIKLYERLEEETGQVVGFHQPGSIRLATTPERVDEFKYQMTRTNWHATEQYIIE 158
             +  ++  +   +E+      G     ++                  +N  +  Q++I+
Sbjct: 54  AAVFDETDSIDSHVEDTLIAGAGICDRHAVEFV--------------ASNARSCVQWLID 99

Query: 159 PEKIHELFPLLNMDKILAGLYNPGDGHIDPYSLTMALATGARKYGVLLKYPAPVTSLKPR 218
              + +     N ++        G  H        A         V      P   +  R
Sbjct: 100 QGVLFDTHIQPNGEESYHLTREGGHSHRRILHAADATGREVETTLVSKALNHPNIRVLER 159

Query: 219 PDGTWDVETPQGSVRANRIVNAAGFWA------------REVGKMIGLDHPLI----P-- 260
            +    + + +  +   R V  A  W               V    G          P  
Sbjct: 160 TNAVDLIVSDKIGLPGTRRVVGAWVWNRNKETVETCHAKAVVLATGGASKVYQYTTNPDI 219

Query: 261 ----------------VQHQYVVTSTIPEVKALKRELPVLRDLEGSYYLRQERDGLLFGP 304
                              ++             R   +   L G     +  DG  F P
Sbjct: 220 SSGDGIAMAWRAGCRVANLEFNQFHPTALYHPQARNFLLTEALRGEGAYLKRPDGTRFMP 279

Query: 305 YESQEKMKLQASWVAHGV-------------------PPGFGKELFESDLDRITEH-VEA 344
              +         VA  +                   P  F ++ F    +++    ++ 
Sbjct: 280 DFDERGELAPRDIVARAIDHEMKRLGADCMFLDISHKPADFIRQHFPMIYEKLLGLGIDL 339

Query: 345 AMEMVPVLKKADIINIVNGPITYSPDILPMVGPH--QGVRNYWVAIGFGYGIIHAGGVGK 402
             E VP++  A           Y+   + MV  H    V   +      Y  +H      
Sbjct: 340 TQEPVPIVPAAH----------YTCGGV-MVDDHGRTDVEGLYAIGEVSYTGLHG----- 383

Query: 403 YLSDWILHGEPPFDLIELDPNRYGKWTTTQYTEAKARESYGFNNIVGYPKEERFAGRPTQ 462
             ++ +        L+E     YG W+  +  +   R  Y  +     P +E     P +
Sbjct: 384 --ANLMASN----SLLECLV--YG-WSAAE--DITRRMPYAHDISTLPPWDESRVENPDE 432

Query: 463 RVSGLYKILESKCSMGFHAGWEQPHWFYKPGQDTQYRPSFRRTNWFRPVGSEYKQVMQRV 522
           RV   +   E +  M  + G  +             R   R T   + +   Y       
Sbjct: 433 RVVIQHNWHELRLFMWDYVGIVR-------TTKRLERALRRITMLQQEIDEYYAHFRVSN 485

Query: 523 GVIDLSPFGKF 533
            +++L    + 
Sbjct: 486 NLLELRNLVQV 496


>1VE9-A nrPDB
          Length = 347

 Score = 47.1 bits (110), Expect = 4e-05,   Method: Composition-based stats.
 Identities = 72/394 (18%), Positives = 120/394 (30%), Gaps = 70/394 (17%)

Query: 45  TVIIGGGCVGVSLA------YHLAKAGMRDVVLLEKSELTAGSTWHAAGLTTYFHPGINL 98
            V+IG G +G+S A      YH     +   V  ++      +T  AAGL   +    + 
Sbjct: 3   VVVIGAGVIGLSTALCIHERYHSVLQPLDVKVYADRFTP-FTTTDVAAGLWQPYTSEPSN 61

Query: 99  KKIHYDSIKLYERLEEETGQVVGFHQPGSIRLATTPERVDEFKYQMTRTNWH---ATEQY 155
            +    + + +  L    G       P +  +  TP        +     +         
Sbjct: 62  PQEANWNQQTFNYLLSHIG------SPNAANMGLTPVSGYNLFREAVPDPYWKDMVLGFR 115

Query: 156 IIEPEKIHELFPLLNMDKILAGLYNPGDGHIDPYSLTMALATGARKYGVLLKYPAPVTSL 215
            + P ++ ++FP    D      +      ++       L     + GV       V S 
Sbjct: 116 KLTPREL-DMFP----DYRYG--WFNTSLILEGRKYLQWLTERLTERGVKFFLR-KVESF 167

Query: 216 KPRPDGTWDVETPQGSVRANRIVNAAGFWAREVGKMIGLDHPLIPVQHQYVVTSTIPEVK 275
           +         E  +G   A+ I+N  G WA  +      D  L P + Q ++    P +K
Sbjct: 168 E---------EVARGG--ADVIINCTGVWAGVLQP----DPLLQPGRGQ-IIKVDAPWLK 211

Query: 276 ALKRELPVLRDLEGSYYLRQERDGLLFGPYESQEKMKLQASWVAHGVPPGFGKELFESDL 335
                  + R +  S Y+                   LQA  +      G   E+     
Sbjct: 212 NFIITHDLERGIYNSPYIIP----------------GLQAVTLGGTFQVGNWNEINNIQD 255

Query: 336 DRITEHVEAAMEMVPVLKKADIINIVNGPITYSPDIL------------PMVGPHQGVRN 383
                  E    + P LK A I+    G     P +               V  + G   
Sbjct: 256 HNTI--WEGCCRLEPTLKDAKIVGEYTGFRPVRPQVRLEREQLRFGSSNTEVIHNYGHGG 313

Query: 384 YWVAIGFGYGIIHAGGVGKYLSDWILHGEPPFDL 417
           Y + I +G  +  A   GK L +  L   PP  L
Sbjct: 314 YGLTIHWGCALEVAKLFGKVLEERNLLTMPPSHL 347


>1RP0-A nrPDB
          Length = 284

 Score = 46.7 bits (109), Expect = 5e-05,   Method: Composition-based stats.
 Identities = 21/95 (22%), Positives = 35/95 (36%), Gaps = 6/95 (6%)

Query: 44  ETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKIHY 103
           + V++G G  G+S AY ++K     V ++E+S    G  W   G             +  
Sbjct: 41  DVVVVGAGSAGLSAAYEISKNPNVQVAIIEQSVSPGGGAW-LGGQLFSAMIVRKPAHLFL 99

Query: 104 DSIKLYERLEEETG----QVVGFHQPGSIRLATTP 134
           D I +    E++T         F      +L   P
Sbjct: 100 DEIGVAYD-EQDTYVVVKHAALFTSTIMSKLLARP 133


>3DA1-A nrPDB
          Length = 561

 Score = 46.3 bits (108), Expect = 6e-05,   Method: Composition-based stats.
 Identities = 56/349 (16%), Positives = 110/349 (31%), Gaps = 45/349 (12%)

Query: 40  KDRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWH-----AAGLTTYFHP 94
           + + + ++IGGG  G  +A      G++   L+E ++  +G++         GL      
Sbjct: 16  EKQLDLLVIGGGITGAGIALDAQVRGIQ-TGLVEMNDFASGTSSRSTKLVHGGLRYLKQF 74

Query: 95  GINLKKIHYDSIKLYER-----LEEETGQVVGFHQPGSIRLATTPERVDEFKYQMTRTNW 149
            I L         +           E   +  F      + +T+        Y       
Sbjct: 75  EIKLVAEVGKERAIVYENAPHVTTPEWMLLPIFKDGTFGKFSTSLGLK---VYDYLADVR 131

Query: 150 HATEQYIIEPEKIHELFPLLNMDKIL-AGLYNPGDGHIDPYSLTMALATGARKYGVLLKY 208
               +Y++  ++  E  PLL  + +   G+Y   +   D   LT+ +   A   G +   
Sbjct: 132 KDERRYMLNEKQTLEKEPLLRKENLKGGGIYV--EYRTDDARLTLEIMKEAVARGAVALN 189

Query: 209 PAPVTSLKPRPDGTWDV-------ETPQGSVRANRIVNAAGFWAREVGKMIGLDHPLIPV 261
              V S          V       +T   ++ A ++VNAAG W   + +           
Sbjct: 190 YMKVESFIYDQGKVVGVVAKDRLTDTTH-TIYAKKVVNAAGPWVDTLREKD------RSK 242

Query: 262 QHQYVVTSTIPEVKALKRELPVLRDLEGSYYLRQERDGLLFGPYESQEKMKLQASWVAHG 321
             +Y+       V  +  +      L  + Y   E DG +         +  +       
Sbjct: 243 HGKYLK--LSKGVHLVVDQSRF--PLRQAVYFDTESDGRMI------FAIPREGKTYIGT 292

Query: 322 VPPGFGKELFESDLDRITEH--VEAAMEMVPVLKKA--DIINIVNGPIT 366
               + K++    +        + AA  M P L+    D+ +   G   
Sbjct: 293 TDTFYDKDIASPRMTVEDRDYILAAANYMFPSLRLTADDVESSWAGLRP 341


>5NCC-A nrPDB
          Length = 594

 Score = 46.0 bits (107), Expect = 7e-05,   Method: Composition-based stats.
 Identities = 33/209 (15%), Positives = 63/209 (30%), Gaps = 18/209 (8%)

Query: 32  SPPSPPEWKDRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAGLTTY 91
           S  S P    + + +++GGG     LA  L+  G + V++LE                T 
Sbjct: 13  SDSSSPVAGQKYDYILVGGGTAACVLANRLSADGSKRVLVLEAGPDNTSRDVKIPAAITR 72

Query: 92  FHPGINLKKIHYDSIKLYERLEEETGQVVGFHQPGSIRLATTPERVDEFKY-QMTRTNWH 150
                           L+  L+E+  +   +   G +   ++      +        +  
Sbjct: 73  LFRSP-------LDWNLFSELQEQLAERQIYMARGRLLGGSSATNATLYHRGAAGDYDAW 125

Query: 151 ATEQYIIEPEKIHELFPLLNMDKILA-GLYNPGDGHIDPYS-------LTMALATGARKY 202
             E +    E +   F     +     G Y+   G +   +       L  A    A + 
Sbjct: 126 GVEGW--SSEDVLSWFVQAETNADFGPGAYHGSGGPMRVENPRYTNKQLHTAFFKAAEEV 183

Query: 203 GVLLKYPAPVTSLKPRPDGTWDVETPQGS 231
           G+         S      GT+ V   +G+
Sbjct: 184 GLTPNSDFNDWSHDHAGYGTFQVMQDKGT 212


>3ISH-A nrPDB
          Length = 311

 Score = 44.4 bits (103), Expect = 2e-04,   Method: Composition-based stats.
 Identities = 16/68 (23%), Positives = 30/68 (44%), Gaps = 3/68 (4%)

Query: 44  ETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKIHY 103
           +  IIGGG  G+S   +  + G+++ VL EK       T  +       +PG+       
Sbjct: 3   DCAIIGGGPAGLSAGLYATRGGVKNAVLFEKGMPGGQITGSSE---IENYPGVKEVVSGL 59

Query: 104 DSIKLYER 111
           D ++ ++ 
Sbjct: 60  DFMQPWQE 67


>3R9U-A nrPDB
          Length = 315

 Score = 44.0 bits (102), Expect = 3e-04,   Method: Composition-based stats.
 Identities = 13/42 (30%), Positives = 22/42 (52%)

Query: 44 ETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHA 85
          +  IIGGG  G+S   +  + G+++VV+ EK       T  +
Sbjct: 6  DVAIIGGGPAGLSAGLYATRGGLKNVVMFEKGMPGGQITSSS 47


>1D4E-A nrPDB
          Length = 572

 Score = 44.0 bits (102), Expect = 3e-04,   Method: Composition-based stats.
 Identities = 39/212 (18%), Positives = 69/212 (32%), Gaps = 24/212 (11%)

Query: 40  KDRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAGLTTYFHPGINLK 99
           K+  + VIIG G  G++ A     AG + V+LLEK  +  G+T  AAG           K
Sbjct: 124 KETTDVVIIGSGGAGLAAAVSARDAGAK-VILLEKEPIPGGNTKLAAGGMNAAETKPQAK 182

Query: 100 KIHYDSIKLYERLEEETGQVVGFHQPGSIRLATTPERVDEFKYQMTRTNWHATEQYIIEP 159
                       +E++   ++     G   +        E    +   +  + +   +  
Sbjct: 183 ----------LGIEDKKQIMIDDTMKGGRNI-----NDPELVKVLANNSSDSID--WLTS 225

Query: 160 EKIHELFPLLNMDKILAGLYNPGDGHIDPYSLTMALATGARKYGVLLKYPAPVTSLKPRP 219
                          +   + P  G      +   L   A K G  ++  + V  +    
Sbjct: 226 MGADMTDVGRMGGASVNRSHRPTGGAGVGAHVAQVLWDNAVKRGTDIRLNSRVVRILEDA 285

Query: 220 DGTWDVETPQGSVR------ANRIVNAAGFWA 245
            G       +G         A+ +V AAG +A
Sbjct: 286 SGKVTGVLVKGEYTGYYVIKADAVVIAAGGFA 317


>4DGK-A nrPDB
          Length = 501

 Score = 43.3 bits (100), Expect = 5e-04,   Method: Composition-based stats.
 Identities = 46/281 (16%), Positives = 94/281 (33%), Gaps = 44/281 (15%)

Query: 45  TVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAG-------STWHAAGLTTYFHPGIN 97
           T +IG G  G++LA  L  AG+  ++L ++ +                AG T    P   
Sbjct: 4   TTVIGAGFGGLALAIRLQAAGIPVLLLEQRDKPGGRAYVYEDQGFTFDAGPTVITDPSAI 63

Query: 98  LKKIHYDSIKL-----------YERLEEETGQVVGFHQPGSIRLA----TTPERVDEFKY 142
            +       +L           + RL  E+G+V  +    +   A      P  V+ ++ 
Sbjct: 64  EELFALAGKQLKEYVELLPVTPFYRLCWESGKVFNYDNDQTRLEAQIQQFNPRDVEGYRQ 123

Query: 143 QMTRTNWHATEQYI-------IEPEKIHELFPLLNMDKILAGLYNPGDGHIDPYSLTMAL 195
            +  +     E Y+       +    +    P L   +    +Y+    +I+   L  A 
Sbjct: 124 FLDYSRAVFKEGYLKLGTVPFLSFRDMLRAAPQLAKLQAWRSVYSKVASYIEDEHLRQAF 183

Query: 196 ATGARKYGVLLKYPAPVTSLKPRPDGTWDVETPQGSVRANRIVNAAGFWAREVGKMIGLD 255
           +  +   G      + + +L    +  W V  P+G                 V  MI L 
Sbjct: 184 SFHSLLVGGNPFATSSIYTLIHALEREWGVWFPRG------------GTGALVQGMIKL- 230

Query: 256 HPLIPVQHQYVVTSTIPEVKALKRELPVLRDLEGSYYLRQE 296
                +  + V+ + +  ++    ++  +   +G  +L Q 
Sbjct: 231 --FQDLGGEVVLNARVSHMETTGNKIEAVHLEDGRRFLTQA 269


>5KXJ-A nrPDB
          Length = 557

 Score = 42.5 bits (98), Expect = 7e-04,   Method: Composition-based stats.
 Identities = 34/208 (16%), Positives = 66/208 (31%), Gaps = 25/208 (12%)

Query: 39  WKDRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAGLTTYFHPGINL 98
            +   + +IIG G  G+SLA  LA+     V++L K  ++ GST         F+    +
Sbjct: 5   PELSCDVLIIGSGAAGLSLALRLAEK--HKVIVLSKGPVSEGST---------FYAQGGI 53

Query: 99  KKIHYDSIKLYERLEEETGQVVGFHQPGSIRLATTPERVDEFKYQMTRTNWHATEQYIIE 158
             +  ++  +   +E+      G     ++                  +N     Q++I+
Sbjct: 54  AAVFDETDSIASHVEDTLIAGAGICDRHAVEFV--------------ASNARTCVQWLID 99

Query: 159 PEKIHELFPLLNMDKILAGLYNPGDGHIDPYSLTMALATGARKYGVLLKYPAPVTSLKPR 218
              + +     N  +        G  H        A         V      P   +  R
Sbjct: 100 QGVLFDTHVQPNGKESYHLTREGGHSHRRILHAADATGKEVETTLVSRAQNHPNIQVLER 159

Query: 219 PDGTWDVETPQGSVRANRIVNAAGFWAR 246
            +    + + +  +   R V  A  W R
Sbjct: 160 SNAVDLIISDKMGLPGPRRVVGAWIWNR 187


>6BRD-A nrPDB
          Length = 476

 Score = 42.1 bits (97), Expect = 0.001,   Method: Composition-based stats.
 Identities = 49/231 (21%), Positives = 79/231 (34%), Gaps = 58/231 (25%)

Query: 43  AETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKIH 102
            + +++GGG  G+ LA  L   G+R +VL +++E T  S      + +            
Sbjct: 2   FDVIVVGGGPTGLMLAGELRLHGVRVLVLEKETEPTRQSRAQGLHVRSIE---------V 52

Query: 103 YDSIKLYERLEEETGQVV--GFHQPGSIRLATT-PERVDEFKYQMTRTNWHATEQYIIEP 159
                L ER  E    V   GF       LAT+ PER+D     +              P
Sbjct: 53  MAQRGLLERFLERGHTVAVGGFFAG----LATSWPERLDTAHSYVLAV-----------P 97

Query: 160 EKIHELFPLLNMDKILAGLYNPGDGHIDPYSLTMALATGARKYGVLLKYPAPVTSLKPRP 219
           + I E                              LA  A   G  ++    +  L+   
Sbjct: 98  QVITE----------------------------QLLAEHATALGAEIRRGRALVGLRQDE 129

Query: 220 DGTWDVETPQGS-VRANRIVNAAGFWAREVGKMIGLDHPLIPVQHQYVVTS 269
           DG   V+   G  +RA  +V   G     V K++G+  P  P + + ++  
Sbjct: 130 DGVT-VDLADGEQLRARYVVGCDGG-RSTVRKLLGVAFPGEPSRVETLLGE 178


>4C5O-A nrPDB
          Length = 357

 Score = 42.1 bits (97), Expect = 0.001,   Method: Composition-based stats.
 Identities = 19/87 (21%), Positives = 32/87 (36%), Gaps = 2/87 (2%)

Query: 41  DRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKK 100
           D  + V+IGGG  G+S  Y L ++G+  V+L  ++            L  +   G +   
Sbjct: 2   DSVDVVVIGGGQSGLSAGYFLRRSGLSYVILDAEASPGGAWQHAWHSLHLFSPAGWSSIP 61

Query: 101 IH--YDSIKLYERLEEETGQVVGFHQP 125
                 S   Y    E    +  + Q 
Sbjct: 62  GWPMPASQGPYPARAEVLAYLAQYEQK 88


>4REP-A nrPDB
          Length = 495

 Score = 42.1 bits (97), Expect = 0.001,   Method: Composition-based stats.
 Identities = 17/65 (26%), Positives = 31/65 (47%), Gaps = 3/65 (4%)

Query: 177 GLYNPGDGHIDPYSLTMALATGARKYGVLLKYPAPVTSLKPRPDGTWDVETPQGSVRANR 236
           G Y P  G    + ++ +L   A+K GV  ++   VT++    +    VET  GS  ++ 
Sbjct: 215 GTYYPDGGM---HRISQSLFELAQKVGVKFRFRESVTNITTSKNKVTGVETKNGSYLSDL 271

Query: 237 IVNAA 241
           +V+  
Sbjct: 272 VVSNM 276


>3FPZ-A nrPDB
          Length = 326

 Score = 41.7 bits (96), Expect = 0.001,   Method: Composition-based stats.
 Identities = 22/99 (22%), Positives = 41/99 (41%), Gaps = 6/99 (6%)

Query: 43  AETVIIGGGCVGVSLAYHLAKAGMR-DVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKI 101
           ++ +I+G G  G+S AY +AK      V ++E S    G +W    L   F   +  K  
Sbjct: 66  SDVIIVGAGSSGLSAAYVIAKNRPDLKVCIIESSVAPGGGSWLGGQL---FSAMVMRKPA 122

Query: 102 HYDSIKLYERLEEETGQVVGFHQPGSIRLATTPERVDEF 140
           H    +L   +  E        +  ++ ++T   +V + 
Sbjct: 123 HLFLQEL--EIPYEDEGDYVVVKHAALFISTVLSKVLQL 159


>1C0L-A nrPDB
          Length = 363

 Score = 41.3 bits (95), Expect = 0.002,   Method: Composition-based stats.
 Identities = 53/265 (20%), Positives = 85/265 (32%), Gaps = 45/265 (16%)

Query: 45  TVIIGGGCVGVSLAYHLAKAGMRDVVL-----LEKSELTAGSTWHAAGLT--TYFHPGIN 97
            V++G G +G+S A  LA+ G    +L      + S  T  S W  A  T       G  
Sbjct: 9   VVVLGSGVIGLSSALILARKGYSVHILARDLPEDVSSQTFASPWAGANWTPFMTLTDGPR 68

Query: 98  LKKIHYDSIKLYERLEEETGQVVGFHQPGSIRLATTPERVDEFKYQMTRTNWHATEQYII 157
             K    + K +  L      +      G+ R A   + +          +W+       
Sbjct: 69  QAKWEESTFKKWVELVPTGHAMWL---KGTRRFAQNEDGLL--------GHWYKDITPNY 117

Query: 158 EPEKIHELFPLLNMDKILAGLYNPGDGHIDPYSLTMALATGARKYGVLLKYPAPVTSLKP 217
            P    E  P       +   Y+    H   Y     LA   +K G        VTSL+ 
Sbjct: 118 RPLPSSECPPGA-----IGVTYDTLSVHAPKY--CQYLARELQKLGAT-FERRTVTSLEQ 169

Query: 218 RPDGTWDVETPQGSVRANRIVNAAGFWAREVGKMIGLDHPLIPVQHQYVVTSTIPEVKAL 277
             DG            A+ +VNA G  A+ +  +   D    P++ Q V+  +  +   +
Sbjct: 170 AFDG------------ADLVVNATGLGAKSIAGID--DQAAEPIRGQTVLVKSPCKRCTM 215

Query: 278 KRELPVLRDLEGSYYLRQERDGLLF 302
               P         Y+     G + 
Sbjct: 216 DSSDPAS-----PAYIIPRPGGEVI 235


>1F8S-A nrPDB
          Length = 498

 Score = 41.0 bits (94), Expect = 0.002,   Method: Composition-based stats.
 Identities = 46/286 (16%), Positives = 83/286 (29%), Gaps = 69/286 (24%)

Query: 45  TVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAG-STWHAAGLTTYFHPGIN------ 97
            VI+G G  G+S AY LA AG +  VL           T+       Y + G        
Sbjct: 36  VVIVGAGMAGLSAAYVLAGAGHQVTVLEASERPGGRVRTYRNEEAGWYANLGPMRLPEKH 95

Query: 98  ------LKKIHYDSIKLYERLEEETGQVVGFHQ--------PGSIRLATTPER------- 136
                 ++K      +  +  +     +    +        PG ++    P         
Sbjct: 96  RIVREYIRKFDLRLNEFSQENDNAWYFIKNIRKKVGEVKKDPGLLKYPVKPSEAGKSAGQ 155

Query: 137 ---------VDEFKY----------QMTRTNWHATEQYIIEPEKIHELFPLLNMDKILAG 177
                    V+E K               T  +  ++  + P  +  +  LLN D     
Sbjct: 156 LYEESLGKVVEELKRTNCSYILNKYDTYSTKEYLIKEGDLSPGAVDMIGDLLNEDSGYYV 215

Query: 178 LYNPGDGHIDPYSLTMALATGA-----------RKYGVLLKYPAPVTSLKPRPDGTWDV- 225
            +     H D ++                    R     + + A V  ++        V 
Sbjct: 216 SFIESLKHDDIFAYEKRFDEIVDGMDKLPTAMYRDIQDKVHFNAQVIKIQQNDQKVTVVY 275

Query: 226 -----ETPQGSVRANRIVNAAGFWAREVGKMIGLDHPLIPVQHQYV 266
                ETP  SV A+ ++           ++I  + PL+P +   +
Sbjct: 276 ETLSKETP--SVTADYVIVCT---TSRAVRLIKFNPPLLPKKAHAL 316


>4BK3-A nrPDB
          Length = 424

 Score = 41.0 bits (94), Expect = 0.002,   Method: Composition-based stats.
 Identities = 38/230 (16%), Positives = 68/230 (29%), Gaps = 21/230 (9%)

Query: 190 SLTMALATGARKYGVLLKYPAPVTSLKPRPDGTWDVETPQGSVRANRIVNAAGFWAREVG 249
            L   L   AR  G  L     VT +    D    V T  G      I          + 
Sbjct: 112 DLHATLVDAARAAGAELHTGVTVTDVITEGDKAI-VSTDDGRTHEADIALGMDGLKSRLR 170

Query: 250 KMIGLDHPLIPVQHQYVVTSTIPEVKALKRELPVLRDLEGSYYLRQERDGLLFGPYESQE 309
           + I  D P+      Y  T+   +V+  +    V+  +    +  Q     L G     +
Sbjct: 171 EKISGDEPVSSGYAAYRGTTPYRDVELDEDIEDVVGYIGPRCHFIQYP---LRGGEMLNQ 227

Query: 310 KMKLQASWVAHGVPPGFGKELFESDLDRITEHVEAAMEMVPVLKKADIINIVNGPITYSP 369
               ++    +G+    G E  E       E+V   ++ +         +         P
Sbjct: 228 VAVFESPGFKNGIENWGGPEELEQAYAHCHENVRRGIDYL-------WKDRWWPMYDREP 280

Query: 370 -----DILPMV---GPHQGVRNYWVAIGFGYGIIHAGGVGKYLSDWILHG 411
                D   ++     H  ++  ++A G    I  A  +  Y ++    G
Sbjct: 281 IENWVDGRMILLGDAAHPPLQ--YLASGAVMAIEDAKCLADYAAEDFSTG 328


>5MOG-A nrPDB
          Length = 497

 Score = 40.6 bits (93), Expect = 0.003,   Method: Composition-based stats.
 Identities = 18/75 (24%), Positives = 31/75 (41%), Gaps = 8/75 (10%)

Query: 36  PPEWKDRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAG--------STWHAAG 87
             +     + VI G G  G+S A +LA AG + ++L  +  L             W+  G
Sbjct: 11  SEQPTKPLQVVIAGAGLAGLSTAKYLADAGHKPILLEARDVLGGKIAAWKDEDGDWYETG 70

Query: 88  LTTYFHPGINLKKIH 102
           L  +F    N++ + 
Sbjct: 71  LHIFFGAYPNIQNLF 85


>2BXR-A nrPDB
          Length = 527

 Score = 39.4 bits (90), Expect = 0.006,   Method: Composition-based stats.
 Identities = 19/78 (24%), Positives = 34/78 (43%), Gaps = 1/78 (1%)

Query: 43  AETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGS-TWHAAGLTTYFHPGINLKKI 101
            + V+IGGG  G+S A  L + G+  +VL  +  +   + T     +      G  +   
Sbjct: 14  FDVVVIGGGISGLSAAKLLTEYGVSVLVLEARDRVGGRTYTIRNEHVDYVDVGGAYVGPT 73

Query: 102 HYDSIKLYERLEEETGQV 119
               ++L + L  ET +V
Sbjct: 74  QNRILRLSKELGIETYKV 91


>4Y4M-A nrPDB
          Length = 290

 Score = 39.4 bits (90), Expect = 0.006,   Method: Composition-based stats.
 Identities = 14/31 (45%), Positives = 20/31 (64%)

Query: 43 AETVIIGGGCVGVSLAYHLAKAGMRDVVLLE 73
          A+ VI+G G  G++ A +LAK G + VVL  
Sbjct: 60 ADVVIVGAGPSGLTCARYLAKEGFKVVVLER 90


>1NAA-A nrPDB
          Length = 541

 Score = 39.4 bits (90), Expect = 0.007,   Method: Composition-based stats.
 Identities = 17/77 (22%), Positives = 31/77 (40%), Gaps = 7/77 (9%)

Query: 43  AETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKIH 102
            + +I+G G  G+  A  L++AG + ++L         ST    G      P      + 
Sbjct: 3   YDYIIVGAGPGGIIAADRLSEAGKKVLLLERGGP----STKQTGGTYVA--PWATSSGLT 56

Query: 103 -YDSIKLYERLEEETGQ 118
            +D   L+E L  ++  
Sbjct: 57  KFDIPGLFESLFTDSNP 73


>5MJK-A nrPDB
          Length = 327

 Score = 39.4 bits (90), Expect = 0.007,   Method: Composition-based stats.
 Identities = 21/81 (25%), Positives = 35/81 (43%), Gaps = 4/81 (4%)

Query: 33  PPSPPEWKDRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAGLTTYF 92
           P      + + + VIIG G  G++ A + A++ M+  +LLE+          A       
Sbjct: 15  PRGSHMTEKKYDVVIIGSGPAGMTAAMYTARSEMK-TLLLERGVPGGQMNNTAE---IEN 70

Query: 93  HPGINLKKIHYDSIKLYERLE 113
           +PG         S+K+ E LE
Sbjct: 71  YPGYETIMGPELSMKMAEPLE 91


>5UWY-A nrPDB
          Length = 308

 Score = 39.0 bits (89), Expect = 0.008,   Method: Composition-based stats.
 Identities = 17/72 (23%), Positives = 34/72 (47%), Gaps = 4/72 (5%)

Query: 43  AETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKIH 102
            +T+IIG G  G++ A + A++ +  V ++E+                  +PG +     
Sbjct: 5   YDTLIIGSGPAGMTAALYAARSNL-SVAIIEQGAPGG---QMNNTFDIENYPGYDHISGP 60

Query: 103 YDSIKLYERLEE 114
             ++K+YE LE+
Sbjct: 61  ELAMKMYEPLEK 72


>4UIR-A nrPDB
          Length = 646

 Score = 39.0 bits (89), Expect = 0.008,   Method: Composition-based stats.
 Identities = 22/93 (23%), Positives = 41/93 (44%), Gaps = 4/93 (4%)

Query: 21  PSSAGLREGQESPPSPPEWKDRAETVIIGGGCVGVSLAYHLAKAG---MRDVVLLEKSEL 77
           P S  +   Q +   P +  D ++  IIG G  G+S AY+  + G    +++  LE+  +
Sbjct: 41  PFSDQIGNYQRNKGIPVQSYDNSKIYIIGSGIAGMSAAYYFIRDGHVPAKNITFLEQLHI 100

Query: 78  TAGSTWHAAGLTTYFHPGINLKKIHYDSIKLYE 110
             GS    AG  T  +     +++      L++
Sbjct: 101 DGGSLD-GAGNPTDGYIIRGGREMDMTYENLWD 132


>1O5W-A nrPDB
          Length = 534

 Score = 38.6 bits (88), Expect = 0.010,   Method: Composition-based stats.
 Identities = 17/78 (21%), Positives = 34/78 (43%), Gaps = 1/78 (1%)

Query: 43  AETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGS-TWHAAGLTTYFHPGINLKKI 101
            + V+IGGG  G++ A  L++  +  +VL  +  +   + T     +      G  +   
Sbjct: 22  FDVVVIGGGISGLAAAKLLSEYKINVLVLEARDRVGGRTYTVRNEHVKWVDVGGAYVGPT 81

Query: 102 HYDSIKLYERLEEETGQV 119
               ++L + L  ET +V
Sbjct: 82  QNRILRLSKELGIETYKV 99


>3KVE-A nrPDB
          Length = 486

 Score = 38.6 bits (88), Expect = 0.012,   Method: Composition-based stats.
 Identities = 49/287 (17%), Positives = 89/287 (31%), Gaps = 71/287 (24%)

Query: 45  TVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAG--STWHAAGLTTYFHPGI------ 96
            V++G G  G+S AY LA AG + V +LE SE   G   T   +    Y + G       
Sbjct: 36  VVVVGAGMSGLSAAYVLAGAGHK-VTVLEASERAGGRVRTHRNSKEGWYANLGPMRIPEK 94

Query: 97  -------------NLKKIHYDSIKLYE---RLEEETGQVVGFHQPGSIRLATTPER---- 136
                        NL +   ++   +     + +  G+V     PG ++    P      
Sbjct: 95  HRIVREYIRKFGLNLNEFSQENDNAWYFIKNIRKRVGEVN--KDPGLLKYPVKPSEEGKS 152

Query: 137 ------------VDEFKY----------QMTRTNWHATEQYIIEPEKIHELFPLLNMDKI 174
                       V + K               T  +  ++  + P  +  +  LLN D  
Sbjct: 153 AGQLYEESLGSAVKDLKRTNCSYILNKYDTYSTKEYLIKEGNLSPGAVDMIGDLLNEDSG 212

Query: 175 LAGLYNPGDGHIDPYSLTMALATGA-----------RKYGVLLKYPAPVTSLKPRPDGTW 223
               +     H D ++                    R     +K+ A V  ++   +   
Sbjct: 213 YYVSFIESLKHDDIFAYEKRFDEIVGGMDQLPTSMYRAIEEKVKFNARVIKIQQNANQVT 272

Query: 224 -DVETPQ---GSVRANRIVNAAGFWAREVGKMIGLDHPLIPVQHQYV 266
              +TP+    S  A+ ++           + I  + PL P +   +
Sbjct: 273 VTYQTPEKDTSSNTADYVIVCT---TSRAARRIQFEPPLPPKKQHAL 316


>2JB2-A nrPDB
          Length = 489

 Score = 38.6 bits (88), Expect = 0.013,   Method: Composition-based stats.
 Identities = 24/166 (14%), Positives = 44/166 (26%), Gaps = 22/166 (13%)

Query: 40  KDRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAGLTTYFHPGINLK 99
           K     V++GGG  G+  A+ L KAG +  VL  ++                   G    
Sbjct: 9   KGSHSVVVLGGGPAGLCSAFELQKAGYKVTVLEARTRPGGR--------VWTARGGSEET 60

Query: 100 KIHYDSIKLYERLEEETGQVVGFHQPGSIRLATTPERVDEFKYQMTRTNWHATEQYIIEP 159
            +  ++ K              F +     +  T  R+ +    +        E      
Sbjct: 61  DLSGETQK------------CTFSEGHFYNVGAT--RIPQSHITLDYCRELGVEIQGFGN 106

Query: 160 EKIHELFPLLNMDKILAGLYNPGDGHIDPYSLTMALATGARKYGVL 205
           +  +      +   +            D +     L   A   G L
Sbjct: 107 QNANTFVNYQSDTSLSGQSVTYRAAKADTFGYMSELLKKATDQGAL 152


>3ABT-A nrPDB
          Length = 662

 Score = 38.3 bits (87), Expect = 0.015,   Method: Composition-based stats.
 Identities = 23/124 (18%), Positives = 42/124 (33%), Gaps = 8/124 (6%)

Query: 34  PSPPEWKDRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAGLTTYFH 93
           P P   K   + +IIG G  G++ A  L   GM   +L  +  +         G      
Sbjct: 101 PLPT--KKTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFRKGNYVADL 158

Query: 94  P-----GINLKKIHYDSIKLYERLEEETGQVVGFHQPGSIRLATTPERVD-EFKYQMTRT 147
                 G+    +   S ++   L +   +   +   G        E V+ EF   +  T
Sbjct: 159 GAMVVTGLGGNPMAVVSKQVNMELAKIKQKCPLYEANGQAVPKEKDEMVEQEFNRLLEAT 218

Query: 148 NWHA 151
           ++ +
Sbjct: 219 SYLS 222


>3II4-A nrPDB
          Length = 466

 Score = 38.3 bits (87), Expect = 0.015,   Method: Composition-based stats.
 Identities = 38/268 (14%), Positives = 80/268 (29%), Gaps = 27/268 (10%)

Query: 179 YNPGDGHIDPYSLTMALATGARKYGVLLKYPAPVTSLKPRPDGTWDVETPQGS---VRAN 235
           + P     +   ++  +    +K GV +     V S+           T  G    ++A 
Sbjct: 204 FLPRALPNEDADVSKEIEKQFKKLGVTILTATKVESIADGGSQVTVTVTKDGVAQELKAE 263

Query: 236 RIVNAAGFWAREVG---KMIGLDHPLIPVQHQYVVTSTIPEVKALKRELPVLRDLEGSYY 292
           +++ A GF     G      G+         + +                 +R   G  Y
Sbjct: 264 KVLQAIGFAPNVEGYGLDKAGVAL----TDRKAIGVDD------------YMRTNVGHIY 307

Query: 293 LRQERDGLLFGPYESQEKMKLQASWVAHGVPPGFGKELFESDLDRITEHVEAAMEMVPVL 352
              + +GLL   + ++ +  + A  +A       G             +V A+  +    
Sbjct: 308 AIGDVNGLLQLAHVAEAQGVVAAETIAGAETLTLGDHRMLPRATFCQPNV-ASFGLTEQQ 366

Query: 353 KKADIINIVNGPITYSPDILPM-VGPHQGVRNYWVAIGFGY---GIIHAGGVGKYLSDWI 408
            + +  ++V     ++ +     VG   G          G    G +    V + L +  
Sbjct: 367 ARNEGYDVVVAKFPFTANAKAHGVGDPSGFVKLVADAKHGELLGGHLVGHDVAELLPELT 426

Query: 409 LHGEPPFDLIELDPNRYGKWTTTQYTEA 436
           L         EL  N +   T ++  + 
Sbjct: 427 LAQRWDLTASELARNVHTHPTMSEALQE 454


>2CVJ-A nrPDB
          Length = 180

 Score = 37.9 bits (86), Expect = 0.020,   Method: Composition-based stats.
 Identities = 23/102 (22%), Positives = 43/102 (42%), Gaps = 6/102 (5%)

Query: 44  ETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHA---AGLTTYFHPGINLKK 100
           + +++GGG  G+S A  LA+AG++ V++L+                GL         L++
Sbjct: 3   DVIVVGGGPSGLSAALFLARAGLK-VLVLDGGRSKVKGVSRVPNYPGLLDEPSGEELLRR 61

Query: 101 IHYDSIKLYERLEEETGQVVGFHQPGSIRLATTPERVDEFKY 142
           +   + +     E   G V G    G +    T E V++ + 
Sbjct: 62  LEAHARR--YGAEVRPGVVKGVRDMGGVFEVETEEGVEKAER 101


>2VVL-G nrPDB
          Length = 495

 Score = 37.5 bits (85), Expect = 0.024,   Method: Composition-based stats.
 Identities = 18/70 (25%), Positives = 30/70 (42%), Gaps = 3/70 (4%)

Query: 29 GQESPPSPPEWKDR---AETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHA 85
          G  SPP+  E  D+    + ++IGGG  G++    L  AG + ++L  +  +   S    
Sbjct: 23 GVISPPTNIEDTDKDGPWDVIVIGGGYCGLTATRDLTVAGFKTLLLEARDRIGGRSWSSN 82

Query: 86 AGLTTYFHPG 95
               Y   G
Sbjct: 83 IDGYPYEMGG 92


>5L3D-A nrPDB
          Length = 852

 Score = 37.5 bits (85), Expect = 0.028,   Method: Composition-based stats.
 Identities = 23/124 (18%), Positives = 42/124 (33%), Gaps = 8/124 (6%)

Query: 34  PSPPEWKDRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAGLTTYFH 93
           P P   K   + +IIG G  G++ A  L   GM   +L  +  +         G      
Sbjct: 272 PLPT--KKTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFRKGNYVADL 329

Query: 94  P-----GINLKKIHYDSIKLYERLEEETGQVVGFHQPGSIRLATTPERVD-EFKYQMTRT 147
                 G+    +   S ++   L +   +   +   G        E V+ EF   +  T
Sbjct: 330 GAMVVTGLGGNPMAVVSKQVNMELAKIKQKCPLYEANGQAVPKEKDEMVEQEFNRLLEAT 389

Query: 148 NWHA 151
           ++ +
Sbjct: 390 SYLS 393


>3WE0-A nrPDB
          Length = 580

 Score = 37.1 bits (84), Expect = 0.030,   Method: Composition-based stats.
 Identities = 16/51 (31%), Positives = 24/51 (47%), Gaps = 1/51 (1%)

Query: 35  SPPEWKDRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHA 85
           S P  +   E  I+G G  G+  AY L K G++ V + E S++       A
Sbjct: 58  SIPAARHGEEVAIVGAGIAGLVAAYELMKLGLKPV-VYEASKMGGRLRSQA 107


>1MDA-H nrPDB
          Length = 368

 Score = 37.1 bits (84), Expect = 0.034,   Method: Composition-based stats.
 Identities = 25/99 (25%), Positives = 35/99 (35%), Gaps = 4/99 (4%)

Query: 385 WVAIGFGYGIIHAGGVGKYLS-DWILHGEPPFDLIELDPNRYGKWTTTQYTEAKARESYG 443
           WV+   G G+     +G +LS     H    F L      R  K   T Y E     ++ 
Sbjct: 49  WVSCA-GCGVTLGHSLGAFLSLAVAGHSGSDFALASTSFARSAKGKRTDYVEVFDPVTFL 107

Query: 444 FNNIVGYPKEERFAGRPTQRVSGLYKILESKCSMGFHAG 482
               +  P   RF+  P  RV  +     S C + F  G
Sbjct: 108 PIADIELPDAPRFSVGP--RVHIIGNCASSACLLFFLFG 144


>5ZYN-B nrPDB
          Length = 471

 Score = 37.1 bits (84), Expect = 0.034,   Method: Composition-based stats.
 Identities = 37/218 (16%), Positives = 73/218 (33%), Gaps = 38/218 (17%)

Query: 45  TVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKIHYD 104
            V+IG G  G++ +  L       VVLL+K+    G++  A+      H          D
Sbjct: 7   VVVIGSGLAGLTTSNRLISKYRIPVVLLDKAASIGGNSIKASSGINGAHTDTQQNLKVMD 66

Query: 105 SIKLYERLEEETGQVVGFHQPGSIRLATTPERVDEFKYQMTRTNWHATEQYIIEPEKIHE 164
           + +L+  L++      G    G   L     +  +         W  TE  +        
Sbjct: 67  TPELF--LKDTLHSAKG---RGVPSLMDKLTKESKS-----AIRWLQTEFDL-------- 108

Query: 165 LFPLLNMDKILAGLYNPG----DGHIDP-YSLTMALATGAR------KYGVLLKYPAPVT 213
               L++   L G   P      G + P + +  AL+   +         V +   + V 
Sbjct: 109 ---KLDLLAQLGGHSVPRTHRSSGKLPPGFEIVQALSKKLKDISSKDSNLVQIMLNSEVV 165

Query: 214 SLKPRPDGTW------DVETPQGSVRANRIVNAAGFWA 245
            ++    G        D    +  ++++ +V  +G + 
Sbjct: 166 DIELDNQGHVTGVVYMDENGNRKIMKSHHVVFCSGGFG 203


>1REO-A nrPDB
          Length = 486

 Score = 37.1 bits (84), Expect = 0.036,   Method: Composition-based stats.
 Identities = 48/287 (16%), Positives = 88/287 (30%), Gaps = 71/287 (24%)

Query: 45  TVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAG--STWHAAGLTTYFHPGI------ 96
            V++G G  G+S AY L+ AG + V +LE SE   G   T+       Y + G       
Sbjct: 36  VVVVGAGMSGLSAAYVLSGAGHQ-VTVLEASERAGGRVRTYRNDKEDWYANLGPMRLPEK 94

Query: 97  -------------NLKKIHYDSIKLYE---RLEEETGQVVGFHQPGSIRLATTPER---- 136
                         L +   ++   +     + +  G+V     PG ++    P      
Sbjct: 95  HRIVREYIRKFGLQLNEFSQENDNAWYFIKNIRKRVGEVK--KDPGVLKYPVKPSEEGKS 152

Query: 137 ------------VDEFKY----------QMTRTNWHATEQYIIEPEKIHELFPLLNMDKI 174
                       V+E K               T  +  ++  + P  +  +  L+N D  
Sbjct: 153 AGQLYEESLGKVVEELKRTNCSYILNKYDTYSTKEYLLKEGNLSPGAVDMIGDLMNEDSG 212

Query: 175 LAGLYNPGDGHIDPYSLTMALATGA-----------RKYGVLLKYPAPVTSLKPRPDGTW 223
               +     H D ++                    R     +   A V  ++   +   
Sbjct: 213 YYVSFPESLRHDDIFAYEKRFDEIVGGMDKLPTSMYRAIEEKVHLNAQVIKIQKNAEKVT 272

Query: 224 DV-ETPQ---GSVRANRIVNAAGFWAREVGKMIGLDHPLIPVQHQYV 266
            V +TP     SV A+ ++           + I  + PL P +   +
Sbjct: 273 VVYQTPAKEMASVTADYVIVCT---TSRATRRIKFEPPLPPKKAHAL 316


>1SEZ-A nrPDB
          Length = 504

 Score = 37.1 bits (84), Expect = 0.037,   Method: Composition-based stats.
 Identities = 13/48 (27%), Positives = 20/48 (41%), Gaps = 2/48 (4%)

Query: 34 PSPPEWKDRA--ETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTA 79
          PS  E K  +     +IG G  G++ AY L   G+   V   + +   
Sbjct: 3  PSAGEDKHSSAKRVAVIGAGVSGLAAAYKLKIHGLNVTVFEAEGKAGG 50


>2IVE-A nrPDB
          Length = 478

 Score = 36.7 bits (83), Expect = 0.038,   Method: Composition-based stats.
 Identities = 13/42 (30%), Positives = 21/42 (50%)

Query: 44 ETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHA 85
             ++GGG  G+++A+HL   G   V+L   + L      HA
Sbjct: 18 NVAVVGGGISGLAVAHHLRSRGTDAVLLESSARLGGAVGTHA 59


>3JSK-A nrPDB
          Length = 344

 Score = 36.7 bits (83), Expect = 0.040,   Method: Composition-based stats.
 Identities = 17/95 (17%), Positives = 30/95 (31%), Gaps = 5/95 (5%)

Query: 44  ETVIIGGGCVGVSLAYHLAK-AGMRDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKIH 102
           + VI+G G  G+S AY L+       + ++E      G  W   G             + 
Sbjct: 81  DIVIVGAGSCGLSAAYVLSTLRPDLRITIVEAGVAPGGGAW-LGGQLFSAMVMRKPADVF 139

Query: 103 YDSIKLYERLEEE---TGQVVGFHQPGSIRLATTP 134
            D + +    E +         F      ++   P
Sbjct: 140 LDEVGVPYEDEGDYVVVKHAALFTSTVLSKVLQRP 174


>3IHG-A nrPDB
          Length = 535

 Score = 36.7 bits (83), Expect = 0.043,   Method: Composition-based stats.
 Identities = 10/31 (32%), Positives = 20/31 (64%)

Query: 44 ETVIIGGGCVGVSLAYHLAKAGMRDVVLLEK 74
          + +++G G  G+S A  LA+ G+R +V+  +
Sbjct: 7  DVLVVGAGLGGLSTAMFLARQGVRVLVVERR 37


>1JWB-B nrPDB
          Length = 249

 Score = 36.7 bits (83), Expect = 0.044,   Method: Composition-based stats.
 Identities = 11/64 (17%), Positives = 28/64 (43%)

Query: 38  EWKDRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAGLTTYFHPGIN 97
           E    +  +I+G G +G + + +LA AG+ ++ LL+   ++  +       +        
Sbjct: 27  EALKDSRVLIVGLGGLGCAASQYLASAGVGNLTLLDFDTVSLSNLQRQTLHSDATVGQPK 86

Query: 98  LKKI 101
           ++  
Sbjct: 87  VESA 90


>4EIQ-A nrPDB
          Length = 549

 Score = 36.7 bits (83), Expect = 0.044,   Method: Composition-based stats.
 Identities = 46/221 (20%), Positives = 74/221 (33%), Gaps = 48/221 (21%)

Query: 44  ETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKIHY 103
           + +I+GGG VG++LA  LA   +  +V+              AG  T  HP   +  I  
Sbjct: 28  DVLILGGGPVGMALALDLAHRQVGHLVVD-------------AGDGTITHP--KVSTIGP 72

Query: 104 DSIKLYERLEEETGQVVGFHQPGSIRLATTPERVDEFKYQMTRTNWHATEQYIIEPEKIH 163
            S++L+ R                         V +          H  +   +     H
Sbjct: 73  RSMELFRRW-----------------------GVAKQIRTAGWPGDHPLDAAWVTRVGGH 109

Query: 164 ELF--PLLNMDKILAGLYNPGDGHIDPYSLTMALATGARKYGVLLKYPAPVTSLKPRPDG 221
           E++  PL   D      + P    I P          A   G  L+  + + S + R D 
Sbjct: 110 EVYRIPLGTADTRATPEHTPEPDAICPAH--WLAPLLAEAVGERLRTRSRLDSFEQRDDH 167

Query: 222 T----WDVET-PQGSVRANRIVNAAGFWAREVGKMIGLDHP 257
                 D+ T    +V A  +V   G  +    K +G+D P
Sbjct: 168 VRATITDLRTGATRAVHARYLVACDGA-SSPTRKALGIDAP 207


>3MJ4-A nrPDB
          Length = 397

 Score = 36.7 bits (83), Expect = 0.045,   Method: Composition-based stats.
 Identities = 20/92 (21%), Positives = 38/92 (41%), Gaps = 3/92 (3%)

Query: 27  REGQESPPSPPEWKDRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAA 86
           R  Q +  +  +     + +I+G G  G  LA  LA +G R +++  +  +   +     
Sbjct: 14  RTEQTNTTNEQQESKGFDYLIVGAGFAGSVLAERLASSGQRVLIVDRRPHIGGNAYDCYD 73

Query: 87  GLTTYFHP-GINLKKIHYDSIKLYERLEEETG 117
                 HP G ++   H +S  ++E L   T 
Sbjct: 74  DAGVLIHPYGPHI--FHTNSKDVFEYLSRFTE 103


>3UP5-A nrPDB
          Length = 545

 Score = 36.7 bits (83), Expect = 0.047,   Method: Composition-based stats.
 Identities = 23/124 (18%), Positives = 48/124 (38%), Gaps = 10/124 (8%)

Query: 44  ETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAGLTTYFHPGINL-KKIH 102
           + V+IG G  G+  A+ + +AGM+ + +    ++     W+        +PG  L  + +
Sbjct: 11  DAVVIGAGVTGIYQAFLINQAGMKVLGIEAGEDVGGTWYWN-------RYPGCRLDTESY 63

Query: 103 YDSIKLYERLEEETGQVVGF-HQPGSIRLATTPERVDEFKYQMTRTNWHATEQYIIEPEK 161
                  + +  E      F  QP  +R         + +    R N   T    +E ++
Sbjct: 64  AYGYFALKGIIPEWEWSENFASQPEMLRYVNRAADAMDVRKHY-RFNTRVTAARYVENDR 122

Query: 162 IHEL 165
           + E+
Sbjct: 123 LWEV 126


>4K2X-A nrPDB
          Length = 523

 Score = 36.7 bits (83), Expect = 0.048,   Method: Composition-based stats.
 Identities = 44/223 (19%), Positives = 70/223 (31%), Gaps = 57/223 (25%)

Query: 42  RAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKI 101
           R + VI G G  G+ LA  L  AG R +VL   +E    S                   +
Sbjct: 22  RYDVVIAGAGPTGLMLACELRLAGARTLVLERLAEPVDFS---------------KALGV 66

Query: 102 HYDSIKLYE--RLEEETGQVVGFHQPGSIRLATTPERVDEFKYQMTRTNWHATEQYIIEP 159
           H  +++L +   L E         + G+      P     F  +     +          
Sbjct: 67  HARTVELLDMRGLGEGFQAEAPKLRGGNFASLGVPLDFSSFDTRHPYALF---------- 116

Query: 160 EKIHELFPLLNMDKILAGLYNPGDGHIDPYSLTMALATGARKYGVLLKYPAPVTSLKPRP 219
                  P +  +++L G                     A + G  L+    VT+L+   
Sbjct: 117 ------VPQVRTEELLTG--------------------RALELGAELRRGHAVTALEQDA 150

Query: 220 DGTW-DVETPQGSVRAN--RIVNAAGFWAREVGKMIGLDHPLI 259
           DG    V  P+G        +V   G     V K++G+D P  
Sbjct: 151 DGVTVSVTGPEGPYEVECAYLVGCDGG-GSTVRKLLGIDFPGQ 192


>3L1R-A nrPDB
          Length = 478

 Score = 36.7 bits (83), Expect = 0.048,   Method: Composition-based stats.
 Identities = 12/39 (30%), Positives = 24/39 (61%)

Query: 45 TVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTW 83
           +++G G  G+S A  L++AG+ D+++LE ++   G   
Sbjct: 7  VIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRMH 45


>4JNQ-A nrPDB
          Length = 345

 Score = 36.7 bits (83), Expect = 0.049,   Method: Composition-based stats.
 Identities = 50/364 (13%), Positives = 102/364 (28%), Gaps = 47/364 (12%)

Query: 25  GLREGQESPPSPPEWKDRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWH 84
           G  E Q   P     +  A  ++IG G  G + A + A+A ++ VV+         +   
Sbjct: 10  GTLEAQTQGPGSMT-QRHAPVIVIGSGPAGYTAAIYAARAMLKPVVI---------AGLQ 59

Query: 85  AAGLTTYFHPGINLKKIHYDSIKLYERLEEETGQVVGFHQPGSIRLATTPERVDEFKYQM 144
             G         N           +   +          Q     +      V  F+ + 
Sbjct: 60  QGGQLMITTDVENYPGYAEPVQGPWMMEQMARQAENVGAQIVHDIITEVETTVRPFRLKG 119

Query: 145 TRTNWHATEQYIIEPEKIHELFPLLNMDKILAGLYNPGDGHIDPYSLTMALATGARKYGV 204
                +  +  +I        +  L  ++   G      G +   +         +   V
Sbjct: 120 DSGTIYTCDA-LIIATGAQAKWLGLESEQTFMG------GGVSACATCDGFFYRGKDVVV 172

Query: 205 LLKYPAPVTS--LKPRPDGTWDVETPQGSVRANRIV--------NAAGFWAREVGKMIGL 254
           +      V           +  +   +   RA +I+        N +  W   + +++G 
Sbjct: 173 VGGGNTAVEEALYLSHIAKSVTIVHRRDGFRAEKIMQDRLLSRENVSVVWNSVIDEILGT 232

Query: 255 D-HP-----LIPVQHQYVVTSTIPEVKALKRELPVLRDLEGSYY---LRQERDGLLFGPY 305
           +  P     +  V+ + +VT    E       + +      S +   L+Q+ +G L+   
Sbjct: 233 EARPPMGATVTGVRLKNIVTGETQERATHGVFIAIGHAPAVSLFEGKLKQKPNGYLWTAP 292

Query: 306 ESQEKMKLQASWVAHGVPPGFGKELFESDLDRITEHVEAAMEMVPVLKKADIINIVNGPI 365
                        A  VP  F       D+ R      A M  +  L+    +       
Sbjct: 293 ----------DSTATDVPGIFAAGDVTDDIYR-QAVTAAGMGCMAALEAERWLAAQEPLH 341

Query: 366 TYSP 369
             + 
Sbjct: 342 EAAE 345


>5TUK-A nrPDB
          Length = 408

 Score = 36.3 bits (82), Expect = 0.057,   Method: Composition-based stats.
 Identities = 15/101 (14%), Positives = 30/101 (29%), Gaps = 5/101 (4%)

Query: 45  TVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKIHYD 104
            ++IG G  G ++ Y L + G   +++   + L      HA  +            I+  
Sbjct: 28  ILVIGAGIAGPAVCYWLRRFGFSPILVERCANL--RKGGHAVDIRGVAIDLAKSMGIYKK 85

Query: 105 SIKLYERLEEETGQVVG---FHQPGSIRLATTPERVDEFKY 142
              +  ++E            H+    R         E   
Sbjct: 86  ICNMRTQVELGRYVDAEGNILHEEKGERFGFREGDDIEILR 126


>4B1B-A nrPDB
          Length = 542

 Score = 36.3 bits (82), Expect = 0.063,   Method: Composition-based stats.
 Identities = 20/103 (19%), Positives = 36/103 (34%), Gaps = 12/103 (11%)

Query: 43  AETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAGL---------TTYFH 93
            + V+IGGG  G++ A   A  G R ++       + G+ W   G              +
Sbjct: 43  YDYVVIGGGPGGMASAKEAAAHGARVLLFDYVKPSSQGTKWGIGGTCVNVGCVPKKLMHY 102

Query: 94  PGINLKKIHYDSIK---LYERLEEETGQVVGFHQPGSIRLATT 133
            G        DS      ++ L+ +  ++V   Q     L  +
Sbjct: 103 AGHMGSIFKLDSKAYGWKFDNLKHDWKKLVTTVQSHIRSLNFS 145


>3BI4-A nrPDB
          Length = 516

 Score = 36.3 bits (82), Expect = 0.064,   Method: Composition-based stats.
 Identities = 45/295 (15%), Positives = 87/295 (29%), Gaps = 65/295 (22%)

Query: 36  PPEWKDRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTA---------------- 79
            P  K     +IIG G  G+  A  L + G++D ++LE  +                   
Sbjct: 5   SPAKKK---VIIIGAGIAGLKAASTLHQNGIQDCLVLEARDRVGGRLQTVTGYQGRKYDI 61

Query: 80  GSTWHAAGLTTYFHPG-----------------------INLKKIHYDSIKLYERL---E 113
           G++WH   LT                                +       +L   +   E
Sbjct: 62  GASWHHDTLTNPLFLEEAQLSLNDGRTRFVFDDDNFIYIDEERGRVDHDKELLLEIVDNE 121

Query: 114 EETGQVVGFHQPGSIRLATTPERVDEFKYQMTRTNWHATEQYIIEPEKIHEL-------F 166
                 + FHQ   + ++         KY + R  +   +Q    P+    L       +
Sbjct: 122 MSKFAELEFHQ--HLGVSDCSFFQLVMKYLLQRRQFLTNDQIRYLPQLCRYLELWHGLDW 179

Query: 167 PLLNMDKILAGLYNPGDGHIDPYSLTMALATGARKYGVLLKYPAPVTSLKPRPDGTWDVE 226
            LL+      G        ++  S+   +A    +  + L     V S+   P     V 
Sbjct: 180 KLLSAKDTYFGHQGRNAFALNYDSVVQRIAQSFPQNWLKL--SCEVKSITREPSKNVTVN 237

Query: 227 TPQGS-VRANRIVNAAGFWAREVGKMIGLDHPLIPVQHQYVVTSTIPEVKALKRE 280
              G+   A+ ++               L+  + P ++        P +K + ++
Sbjct: 238 CEDGTVYNADYVIITV--------PQSVLNLSVQPEKNLRGRIEFQPPLKPVIQD 284


>4RPJ-A nrPDB
          Length = 399

 Score = 35.9 bits (81), Expect = 0.069,   Method: Composition-based stats.
 Identities = 20/131 (15%), Positives = 48/131 (36%), Gaps = 11/131 (8%)

Query: 42  RAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAG-------LTTYFHP 94
           R +  ++G G  G+++A  +A    + V++LE+     G+ +  A             H 
Sbjct: 7   RFDLFVVGSGFFGLTIAERVATQLDKRVLVLERRPHIGGNAYSEAEPQTGIEVHKYGAHL 66

Query: 95  GINLKKIHYDSIKLYERLEEETGQVVGFHQPGSIRLATTPERVDEFKYQMTRTNWHATEQ 154
                K  +D ++ +    +   +V   H   + +       V +F  +     +   + 
Sbjct: 67  FHTSNKRVWDYVRQFTDFTDYRHRVFAMHNGQAYQFPMGLGLVSQFFGKY----FTPEQA 122

Query: 155 YIIEPEKIHEL 165
             +  E+  E+
Sbjct: 123 RQLIAEQAAEI 133


>4IV9-A nrPDB
          Length = 557

 Score = 35.9 bits (81), Expect = 0.069,   Method: Composition-based stats.
 Identities = 15/39 (38%), Positives = 21/39 (53%)

Query: 45 TVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTW 83
            I+G G  G+  A  L +AG++DVVL E  +   G  W
Sbjct: 41 VAIVGAGISGLVAATELLRAGVKDVVLYESRDRIGGRVW 79


>3NK2-X nrPDB
          Length = 431

 Score = 35.9 bits (81), Expect = 0.077,   Method: Composition-based stats.
 Identities = 19/98 (19%), Positives = 34/98 (34%), Gaps = 1/98 (1%)

Query: 43  AETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKIH 102
            + +++GGG  G+  A  L  AG + ++L     L   +    +         I    +H
Sbjct: 2   YDAIVVGGGFSGLKAARDLTNAGKKVLLLEGGERLGGRAYSRESRNVPGLRVEIGGAYLH 61

Query: 103 YDSI-KLYERLEEETGQVVGFHQPGSIRLATTPERVDE 139
                +L   L+          +  S R    P  VD+
Sbjct: 62  RKHHPRLAAELDRYGIPTAAASEFTSFRHRLGPTAVDQ 99


>6J0Z-C nrPDB
          Length = 491

 Score = 35.9 bits (81), Expect = 0.081,   Method: Composition-based stats.
 Identities = 42/220 (19%), Positives = 72/220 (32%), Gaps = 59/220 (26%)

Query: 43  AETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKIH 102
           ++ V++G G  G+ LA  L  AG+  VVL + +E                      + + 
Sbjct: 6   SDVVVVGAGPTGLMLAGELRLAGVSVVVLDKLAEP-----------------IKESRALG 48

Query: 103 YDSIKLYERLEEETGQVVGFHQPGSIRLATTPERVDEFKYQMTRTNWHATEQYIIEPEKI 162
           + S +  E   +  G +  F + G I +           YQ+     +            
Sbjct: 49  F-SARTIEEFAQR-GLMDRFGEVGVIPVGHF--GGVPLDYQVIEGGSYGARG-------- 96

Query: 163 HELFPLLNMDKILAGLYNPGDGHIDPYSLTMALATGARKYGVLLKYPAPVTSLKPRPDGT 222
               P    + IL G                     AR+ G  ++    VT+++      
Sbjct: 97  ---IPQARTEGILGGW--------------------ARELGAEVRRGYEVTAIEDTGTSV 133

Query: 223 WDVETPQG-----SVRANRIVNAAGFWAREVGKMIGLDHP 257
             VE         S+RA  +V   G  +  V K+ G+D P
Sbjct: 134 T-VEAAGADGSPLSLRARYVVGCDGARSS-VRKLAGIDFP 171


>4Y4N-A nrPDB
          Length = 286

 Score = 35.6 bits (80), Expect = 0.087,   Method: Composition-based stats.
 Identities = 12/30 (40%), Positives = 19/30 (63%)

Query: 44 ETVIIGGGCVGVSLAYHLAKAGMRDVVLLE 73
          +  I+GGG  G++ A ++AK G + VVL  
Sbjct: 54 DVAIVGGGPSGLTAARYIAKEGYKVVVLER 83


>6CR0-A nrPDB
          Length = 440

 Score = 35.6 bits (80), Expect = 0.10,   Method: Composition-based stats.
 Identities = 7/42 (16%), Positives = 19/42 (45%)

Query: 40 KDRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGS 81
          +   + +++G G  G+  A  L+  G   +++  +  L   +
Sbjct: 6  EKIYDAIVVGAGFSGLVAARELSAQGRSVLIIEARHRLGGRT 47


>3RHA-A nrPDB
          Length = 482

 Score = 35.2 bits (79), Expect = 0.11,   Method: Composition-based stats.
 Identities = 16/40 (40%), Positives = 23/40 (57%), Gaps = 1/40 (2%)

Query: 44 ETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTW 83
          + VI+G G  G++ A  L KAG+  V +LE  +   G TW
Sbjct: 9  DVVIVGAGPSGLTAARELKKAGL-SVAVLEARDRVGGRTW 47


>4N9X-A nrPDB
          Length = 411

 Score = 35.2 bits (79), Expect = 0.13,   Method: Composition-based stats.
 Identities = 21/73 (28%), Positives = 33/73 (45%), Gaps = 5/73 (6%)

Query: 41  DRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEK-SELTAGSTWHAAGLTTYFHPGINLK 99
              + VI GGG VG++LA  L  +G+R  VL ++ +E       HA  ++        L 
Sbjct: 2   QSFDVVIAGGGMVGLALACGLQGSGLRIAVLEKQAAEPQTLGKGHALRVSAINAASECL- 60

Query: 100 KIHYDSIKLYERL 112
                 I ++E L
Sbjct: 61  ---LRHIGVWENL 70


>4USR-A nrPDB
          Length = 361

 Score = 35.2 bits (79), Expect = 0.13,   Method: Composition-based stats.
 Identities = 19/113 (16%), Positives = 37/113 (32%), Gaps = 23/113 (20%)

Query: 33  PPSPPEWKDRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAGLTTYF 92
           P  PP      + ++IGGG   ++ AY L +  +  ++L E+             L    
Sbjct: 2   PAMPP----ILDVIVIGGGQAALTTAYFLRRTSLSYLLLDEQPGPGGAWLHAWDSLRL-- 55

Query: 93  HPGINLKKIHYDSIKLYERLEEETGQVVGFHQPGSIRLATTPERVDEFKYQMT 145
                     + SI  +         +    +PG+     T   V ++  +  
Sbjct: 56  -----FSPAAWSSIAGW--------PMPSPTEPGN----PTRNDVIDYLRRYE 91


>5EVY-X nrPDB
          Length = 438

 Score = 34.8 bits (78), Expect = 0.15,   Method: Composition-based stats.
 Identities = 63/428 (14%), Positives = 116/428 (27%), Gaps = 77/428 (17%)

Query: 40  KDRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAGLTTYFHPGINLK 99
           K      +IGGG  G +LA  L+K+   +V L E +    G                   
Sbjct: 20  KSPLRVAVIGGGIAGTALALGLSKSSHVNVKLFETA-PAFGEIGAG-------------V 65

Query: 100 KIHYDSIKLYERLEEETGQVVGFHQPGSIRLATTPERVDEFKYQMTRTNWHATEQYIIEP 159
               ++++  +RL                        + +     T   W        E 
Sbjct: 66  SFGVNAVEAIQRLG--------------------IGELYKSVADSTPAPWQDI---WFEW 102

Query: 160 EKIHELFPLLNMDKILAGLYNPGDGHI------DPYSLTMALATGARKYGVLLKYPAPVT 213
              H+         ++     PG G            L   L  G    G  +       
Sbjct: 103 RHAHDA-------SLVGATVAPGIGQSSIHRADFIDMLEKRLPAGIASLGKHVVDYTE-- 153

Query: 214 SLKPRPDGTWDVETPQGSVRANRIVNAAGFWARE---VGKMIGLDHPLIP-------VQH 263
                 +G         +  A+  + A G  +     + +  G D  + P        + 
Sbjct: 154 ----NAEGVTLNFADGSTYTADVAIAADGIKSSMRNTLLRAAGHD-AVHPQFTGTSAYRG 208

Query: 264 QYVVTSTIPEVKALKRELPVLRD------LEGSYYLRQERDGLLFGPYESQEKMKLQASW 317
               ++     +A   +  +L         +G       + G L           +    
Sbjct: 209 LVETSALREAYQAASLDEHLLNVPQMYLIEDGHVLTFPVKKGKLIIIVAFVSDRSVAKPQ 268

Query: 318 VAHGVPPGFGKELFESDLDRITEHVEAAMEMVPVLKKADI--INIVNGPITYSPDILPMV 375
                 P       +  L R     EA   ++  +K   +  ++  +   TY    + ++
Sbjct: 269 WPSD-QPWVRPATTDEMLHRFAGAGEAVKTLLTSIKSPTLWALHDFDPLPTYVHGRVALI 327

Query: 376 GPHQGVRNYWVAIGFGYGIIHAGGVGKYLSD-WILHGEPPFDLIELDPNRYGKWTTTQYT 434
           G            G G G+  A  + + L +      + P  L   D  R G+ +  Q T
Sbjct: 328 GDAAHAMLPHQGAGAGQGLEDAYFMAELLGNPLHEASDIPALLEVYDDVRRGRASKVQLT 387

Query: 435 EAKARESY 442
             +A E Y
Sbjct: 388 SREAGELY 395


>5TUM-A nrPDB
          Length = 410

 Score = 34.8 bits (78), Expect = 0.15,   Method: Composition-based stats.
 Identities = 18/95 (18%), Positives = 34/95 (35%), Gaps = 11/95 (11%)

Query: 41  DRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTW--------HAAGLTTYF 92
              + ++IG G  G ++ Y L + G   V++ + + +  G           H A     +
Sbjct: 24  KNIKILVIGAGVAGPAVCYWLRRFGFSPVLIEKYASIRKGGQALDVRGIATHIAREMGIY 83

Query: 93  HPGINLKKIHYDSIKLYER---LEEETGQVVGFHQ 124
                ++        +      L EE G+  GF Q
Sbjct: 84  DQICEMRTRIERGRFVDSSGKVLHEEQGEKFGFRQ 118


>3CGD-A nrPDB
          Length = 480

 Score = 34.8 bits (78), Expect = 0.15,   Method: Composition-based stats.
 Identities = 38/254 (14%), Positives = 79/254 (31%), Gaps = 61/254 (24%)

Query: 42  RAETVIIGGGCVGVSLAYHLAKAGMR-DVVLLEKSE---------LTAGSTWHAAGLTTY 91
               VIIGG   G+S A  + +     +VV LEK E             S   A+     
Sbjct: 36  SMNYVIIGGDAAGMSAAMQIVRNDENANVVTLEKGEIYSYAQCGLPYVISGAIASTEKLI 95

Query: 92  FHPGINLKKIHYDSIKLYERLEE-ETGQVVGFHQ-------------------------- 124
                  +  +    K+   + + +T + + + +                          
Sbjct: 96  ARNVKTFRDKYGIDAKVRHEVTKVDTEKKIVYAEHTKTKDVFEFSYDRLLIATGVRPVMP 155

Query: 125 -------PGSIRLATTPERVDEFK----YQMTRTNWHATEQYIIEPEK----IHELFPLL 169
                   G   L T P+     K     ++            +E  +    + +   ++
Sbjct: 156 EWEGRDLQGVHLLKTIPDAERILKTLETNKVEDVTIIGGGAIGLEMAETFVELGKKVRMI 215

Query: 170 NMDKILAGLYNPGDGHIDPYSLTMALATGARKYGVLLKYPAPVTSLKPRPDGTWDVETPQ 229
             +  +  +Y   DG +  Y     +   A K+ + +     V + K   +    VET +
Sbjct: 216 ERNDHIGTIY---DGDMAEY-----IYKEADKHHIEILTNENVKAFKGN-ERVEAVETDK 266

Query: 230 GSVRANRIVNAAGF 243
           G+ +A+ ++ + G 
Sbjct: 267 GTYKADLVLVSVGV 280


>4MOP-A nrPDB
          Length = 633

 Score = 34.4 bits (77), Expect = 0.20,   Method: Composition-based stats.
 Identities = 16/54 (29%), Positives = 26/54 (48%), Gaps = 7/54 (12%)

Query: 33 PPSPPEWKD------RAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAG 80
          PP P   K       + + VI+G G +G + A  L  AG + V + +  E+ +G
Sbjct: 31 PPLPGPDKKVPGMDIKYDVVIVGSGPIGCTYARELVGAGYK-VAMFDIGEIDSG 83


>3LOV-A nrPDB
          Length = 475

 Score = 34.4 bits (77), Expect = 0.23,   Method: Composition-based stats.
 Identities = 27/111 (24%), Positives = 44/111 (39%), Gaps = 14/111 (12%)

Query: 46  VIIGGGCVGVSLAYHLAKAGMR-DVVLLEKSELTAG--STWHAAGLTTYFHPGINLKKIH 102
           VI+GGG  G++ AY+  +A    ++ LLE  E   G  +T+   G T    P   + + H
Sbjct: 8   VIVGGGITGLAAAYYAERAFPDLNITLLEAGERLGGKVATYREDGFTIERGPDSYVARKH 67

Query: 103 -----YDSIKLYERLEEETGQVVGFHQPGSIRLATT------PERVDEFKY 142
                 ++I L E+L             G +           P  +D F+ 
Sbjct: 68  ILTDLIEAIGLGEKLVRNNTSQAFILDTGGLHPIPKGAVMGIPTDLDLFRQ 118


>6N7F-A nrPDB
          Length = 453

 Score = 34.4 bits (77), Expect = 0.23,   Method: Composition-based stats.
 Identities = 12/38 (31%), Positives = 20/38 (52%), Gaps = 1/38 (2%)

Query: 43 AETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAG 80
           + ++IGGG  G++ A   A  G + V+L E  E+   
Sbjct: 8  YDYIVIGGGSAGIASANRAAMHGAK-VLLAEGKEIGGT 44


>4IA5-A nrPDB
          Length = 591

 Score = 34.0 bits (76), Expect = 0.25,   Method: Composition-based stats.
 Identities = 16/57 (28%), Positives = 24/57 (42%), Gaps = 3/57 (5%)

Query: 34 PSPPEWKDRAETVIIGGGCVGVSLAYHLAKAGM---RDVVLLEKSELTAGSTWHAAG 87
          P  P   D+    IIG G  G+S A  L +       ++ +LE+  +  GS   A  
Sbjct: 14 PKKPAGVDKKSAYIIGSGLAGLSTAVFLVRDAQMKGENIHILEELPVAGGSLDGADR 70


>2Q7V-A nrPDB
          Length = 325

 Score = 34.0 bits (76), Expect = 0.31,   Method: Composition-based stats.
 Identities = 13/41 (31%), Positives = 21/41 (51%), Gaps = 1/41 (2%)

Query: 43 AETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTW 83
           + VIIGGG  G++ A +  +A +   ++LEK        W
Sbjct: 9  YDVVIIGGGPAGLTAAIYTGRAQL-STLILEKGMPGGQIAW 48


>2CUL-A nrPDB
          Length = 232

 Score = 33.6 bits (75), Expect = 0.35,   Method: Composition-based stats.
 Identities = 15/102 (14%), Positives = 32/102 (31%), Gaps = 6/102 (5%)

Query: 43  AETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSE------LTAGSTWHAAGLTTYFHPGI 96
            + +I+G G  G   A+ LA+ G+R  +L +  +      L     +    L    +   
Sbjct: 4   YQVLIVGAGFSGAETAFWLAQKGVRVGLLTQSLDAVMMPFLPPKPPFPPGSLLERAYDPK 63

Query: 97  NLKKIHYDSIKLYERLEEETGQVVGFHQPGSIRLATTPERVD 138
           + +   + +   Y         +      G +        V 
Sbjct: 64  DERVWAFHARAKYLLEGLRPLHLFQATATGLLLEGNRVVGVR 105


>4OVI-A nrPDB
          Length = 542

 Score = 33.6 bits (75), Expect = 0.36,   Method: Composition-based stats.
 Identities = 10/51 (19%), Positives = 22/51 (43%)

Query: 29 GQESPPSPPEWKDRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTA 79
          GQ +  S  +  +  + +++G G  G+   Y L + G    V+    ++  
Sbjct: 3  GQTTVDSRRQPPEEVDVLVVGAGFSGLYALYRLRELGRSVHVIETAGDVGG 53


>1FEC-A nrPDB
          Length = 490

 Score = 33.6 bits (75), Expect = 0.38,   Method: Composition-based stats.
 Identities = 35/209 (16%), Positives = 65/209 (31%), Gaps = 43/209 (20%)

Query: 41  DRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKK 100
              + V+IG G  G+   ++ A    + V +++  +   G   +AA   T  + G   KK
Sbjct: 2   RAYDLVVIGAGSGGLEAGWNAASLHKKRVAVIDL-QKHHGPPHYAALGGTCVNVGCVPKK 60

Query: 101 IHYDSIKLYERLEEETGQVVGFHQPGSIRLATTPERVDEFKYQMTRTNWHATEQYIIEPE 160
           +        + + E      GF                E   +  R NW A         
Sbjct: 61  LMVTGANYMDTIRES----AGF--------------GWELDRESVRPNWKALIA------ 96

Query: 161 KIHELFPLLNMDKILAGLYNPGDGHIDPYSLTMALATGARKYGVLLKYPAPVTSLKPRPD 220
             ++    +N      G++   +G               + +G L      +      P+
Sbjct: 97  AKNKAVSGIN--DSYEGMFADTEGLTFH-----------QGFGALQDNHTVLVRESADPN 143

Query: 221 GTWDVETPQGSVRANRIVNAAGFWAREVG 249
               +ET         I+ A G W + +G
Sbjct: 144 SAV-LETLDTEY----ILLATGSWPQHLG 167


>1V59-A nrPDB
          Length = 478

 Score = 33.3 bits (74), Expect = 0.46,   Method: Composition-based stats.
 Identities = 11/40 (27%), Positives = 17/40 (42%)

Query: 41 DRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAG 80
             + VIIGGG  G   A   A+ G     + ++ +L   
Sbjct: 4  KSHDVVIIGGGPAGYVAAIKAAQLGFNTACVEKRGKLGGT 43


>3VH2-A nrPDB
          Length = 616

 Score = 33.3 bits (74), Expect = 0.47,   Method: Composition-based stats.
 Identities = 18/117 (15%), Positives = 40/117 (34%), Gaps = 6/117 (5%)

Query: 41  DRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKK 100
              + +++G G +G  ++  L   G+R +  ++   ++  +    A L  +   G    +
Sbjct: 326 KNTKVLLLGAGTLGCYVSRALIAWGVRKITFVDNGTVSYSNPVRQA-LYNFEDCGKPKAE 384

Query: 101 IHYDSIKLYERLEEETGQVVGFHQPGSIRLATTPERVDEFKYQMTRTNWHATEQYII 157
           +   S+K    L + TG      +     +       +       R      E  II
Sbjct: 385 LAAASLKRIFPLMDATG-----VKLSIPMIGHKLVNEEAQHKDFDRLRALIKEHDII 436


>3T7E-A nrPDB
          Length = 344

 Score = 33.3 bits (74), Expect = 0.47,   Method: Composition-based stats.
 Identities = 18/117 (15%), Positives = 40/117 (34%), Gaps = 6/117 (5%)

Query: 41  DRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKK 100
              + +++G G +G  ++  L   G+R +  ++   ++  +    A L  +   G    +
Sbjct: 37  KNTKVLLLGAGTLGCYVSRALIAWGVRKITFVDNGTVSYSNPVRQA-LYNFEDCGKPKAE 95

Query: 101 IHYDSIKLYERLEEETGQVVGFHQPGSIRLATTPERVDEFKYQMTRTNWHATEQYII 157
           +   S+K    L + TG      +     +       +       R      E  II
Sbjct: 96  LAAASLKRIFPLMDATG-----VKLSIPMIGHKLVNEEAQHKDFDRLRALIKEHDII 147


>4Z25-A nrPDB
          Length = 652

 Score = 33.3 bits (74), Expect = 0.47,   Method: Composition-based stats.
 Identities = 13/32 (40%), Positives = 19/32 (59%)

Query: 44 ETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKS 75
          + VIIG G  G  LA++LA+     ++LLE  
Sbjct: 8  DIVIIGAGAAGSLLAHYLARFSNMKIILLEAG 39


>1KSU-A nrPDB
          Length = 571

 Score = 33.3 bits (74), Expect = 0.47,   Method: Composition-based stats.
 Identities = 33/196 (16%), Positives = 66/196 (33%), Gaps = 24/196 (12%)

Query: 56  SLAYHLAKAGMRDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKIHYDSIKLYERLEEE 115
           S A     +G + + L+EK  +  G+   AAG            K   DS +L      +
Sbjct: 140 SAAISATDSGAKVI-LIEKEPVIGGNAKLAAGGMNAAWTDQQKAKKITDSPELMFEDTMK 198

Query: 116 TGQVVGFHQPGSIRLATTPERVDEFKYQMTRTNWHATEQYIIEPEKIHELFPLLNMDKIL 175
            GQ +  + P  +++ ++  +  +    MT      T+  ++    ++            
Sbjct: 199 GGQNI--NDPALVKVLSSHSK--DSVDWMTAMGADLTDVGMMGGASVNRA---------- 244

Query: 176 AGLYNPGDGHIDPYSLTMALATGARKYGVLLKYPAPVTSLKPRPDGTWDVETPQGSV--- 232
              + P  G      +   L   A K  + L+       +     GT      +G     
Sbjct: 245 ---HRPTGGAGVGAHVVQVLYDNAVKRNIDLRMNTRGIEVLKDDKGTVKGILVKGMYKGY 301

Query: 233 ---RANRIVNAAGFWA 245
              +A+ ++ A G +A
Sbjct: 302 YWVKADAVILATGGFA 317


>4OEN-A nrPDB
          Length = 223

 Score = 33.3 bits (74), Expect = 0.54,   Method: Composition-based stats.
 Identities = 12/57 (21%), Positives = 25/57 (43%)

Query: 596 DLRWIEEAAVRGGYDVEIRNITDELGVLGVAGPYARRVLQKLTSEDLSDDVFKFLQT 652
           D+  I+  A   G+++EI N   +  +  V    A  ++  ++  D     F F ++
Sbjct: 29  DMELIKAIAKDQGFEIEITNPGFDAAISAVQAGQADGIIAGMSVTDARKATFDFSES 85


>3LXD-A nrPDB
          Length = 415

 Score = 32.9 bits (73), Expect = 0.59,   Method: Composition-based stats.
 Identities = 23/116 (19%), Positives = 43/116 (37%), Gaps = 10/116 (8%)

Query: 133 TPERVDEFKYQMTRTNWHAT---EQYI-IEPEKIHELFPLLNMDKILAGLYNPGD-GHID 187
           T E  D    ++     +A      YI +E   +   F  +N+  +L  L  P     + 
Sbjct: 137 TKEDADRLMAELDAGAKNAVVIGGGYIGLEAAAVLTKF-GVNV-TLLEAL--PRVLARVA 192

Query: 188 PYSLTMALATGARKYGVLLKYPAPVTSLKPRPDGTWDVETPQGS-VRANRIVNAAG 242
             +L+       R +GV L+  A +  ++        V    GS + A+ ++   G
Sbjct: 193 GEALSEFYQAEHRAHGVDLRTGAAMDCIEGDGTKVTGVRMQDGSVIPADIVIVGIG 248


>5EQD-A nrPDB
          Length = 400

 Score = 32.9 bits (73), Expect = 0.61,   Method: Composition-based stats.
 Identities = 18/131 (13%), Positives = 44/131 (33%), Gaps = 11/131 (8%)

Query: 42  RAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAG-------LTTYFHP 94
             +  ++G G  G+++A   A    + V+++E+     G+ +                H 
Sbjct: 4   NFDLFVVGSGFFGLTIAERAATQLGKRVLVIERRPHIGGNAYSEPEPETGIEVHKYGAHL 63

Query: 95  GINLKKIHYDSIKLYERLEEETGQVVGFHQPGSIRLATTPERVDEFKYQMTRTNWHATEQ 154
                K  +D ++ +        +V   H   + +       V +F  +    +    E 
Sbjct: 64  FHTSNKRVWDYVRQFTDFTGYQHRVFAMHNGQAYQFPMGLGLVSQFFGRYFSPD----EA 119

Query: 155 YIIEPEKIHEL 165
             +  E+  E+
Sbjct: 120 RALIAEQASEI 130


>4X4J-A nrPDB
          Length = 507

 Score = 32.9 bits (73), Expect = 0.62,   Method: Composition-based stats.
 Identities = 42/219 (19%), Positives = 62/219 (28%), Gaps = 58/219 (26%)

Query: 43  AETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKIH 102
           A  VI G G  G+ LA  L  AG+  VVL               G T             
Sbjct: 23  APVVIAGAGPAGLMLAGELRLAGIGVVVLERL--PARTGESRGLGFTARTME-------V 73

Query: 103 YDSIKLYERLEEETGQVVGFHQPGSIRLATTPERVDEFKYQMTRTNWHATEQYIIEPE-K 161
           +D   L  R  E      G H  G                          +  +++   +
Sbjct: 74  FDQRGLLRRFGEVQTSDQG-HFGGIP-----------------------VDFGLLDGAHQ 109

Query: 162 IHELFPLLNMDKILAGLYNPGDGHIDPYSLTMALATGARKYGVLLKYPAPVTSLKPRPDG 221
             +  P    + +L                       A + G  ++    +T ++   DG
Sbjct: 110 AAKTIPQSATEAVLEAW--------------------AGELGADIRRGHELTGVRDDGDG 149

Query: 222 T-WDVETPQG--SVRANRIVNAAGFWAREVGKMIGLDHP 257
               V  P G   +RA  +V   G     V K +G D P
Sbjct: 150 VAVTVRGPAGEHVLRAGWLVGCDGG-RSAVRKAVGFDFP 187


>4ZN0-A nrPDB
          Length = 311

 Score = 32.9 bits (73), Expect = 0.65,   Method: Composition-based stats.
 Identities = 11/37 (29%), Positives = 24/37 (64%), Gaps = 1/37 (2%)

Query: 43 AETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTA 79
           + +IIGGG  G++   +  + G+ D ++LE++E++ 
Sbjct: 8  YDLIIIGGGPAGLTAGIYAVRYGL-DTLILERNEISG 43


>1ZFN-A nrPDB
          Length = 253

 Score = 32.9 bits (73), Expect = 0.65,   Method: Composition-based stats.
 Identities = 12/42 (28%), Positives = 23/42 (54%)

Query: 43 AETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWH 84
          ++ +IIG G +G   A +LA AG+  +VL +  ++   +   
Sbjct: 31 SQVLIIGLGGLGTPAALYLAGAGVGTLVLADDDDVHLSNLQR 72


>1UXJ-A nrPDB
          Length = 309

 Score = 32.9 bits (73), Expect = 0.69,   Method: Composition-based stats.
 Identities = 14/32 (43%), Positives = 20/32 (62%)

Query: 42 RAETVIIGGGCVGVSLAYHLAKAGMRDVVLLE 73
          R +  IIG G VG + A+ LA   + D+VLL+
Sbjct: 2  RKKISIIGAGFVGSTTAHWLAAKELGDIVLLD 33


>2NVK-X nrPDB
          Length = 488

 Score = 32.9 bits (73), Expect = 0.70,   Method: Composition-based stats.
 Identities = 15/55 (27%), Positives = 23/55 (41%), Gaps = 1/55 (1%)

Query: 35 SPPEWKDRAETVIIGGGCVGVSLAYHLAKAGMRDVVL-LEKSELTAGSTWHAAGL 88
          +P +     + ++IGGG  G++ A      G R   L   K   T G+ W   G 
Sbjct: 2  APVQGSYDYDLIVIGGGSAGLACAKEAVLNGARVACLDFVKPTPTLGTKWGVGGT 56


>3WSV-A nrPDB
          Length = 322

 Score = 32.5 bits (72), Expect = 0.78,   Method: Composition-based stats.
 Identities = 12/33 (36%), Positives = 20/33 (60%)

Query: 40 KDRAETVIIGGGCVGVSLAYHLAKAGMRDVVLL 72
          K   + VI+G G VG S+AY +   G+ + ++L
Sbjct: 3  KTSRKVVIVGTGFVGTSIAYAMINQGVANELVL 35


>4NQW-A nrPDB
          Length = 204

 Score = 32.5 bits (72), Expect = 0.82,   Method: Composition-based stats.
 Identities = 15/86 (17%), Positives = 38/86 (44%), Gaps = 2/86 (2%)

Query: 632 RVLQKLTSEDLSDDVFKFLQTKSLKISDIPVTAIR-ISYTGELGWELYHRREDSAALYER 690
            +L+++   D +     +  TKS ++  + +  +R   Y+ E   E+Y     +A+ ++ 
Sbjct: 30  ALLRRVAGHDQAAFAEFYDHTKS-RVYGLVMRVLRDTGYSEETTQEIYLEVWRNASEFDS 88

Query: 691 IMNAGQEEGIDNFGTYALNALRLEKA 716
              +     +      A++ +R E+A
Sbjct: 89  AKGSALAWLLTMAHRRAVDRVRCEQA 114


>4IVM-B nrPDB
          Length = 483

 Score = 32.5 bits (72), Expect = 0.82,   Method: Composition-based stats.
 Identities = 26/150 (17%), Positives = 48/150 (32%), Gaps = 16/150 (10%)

Query: 189 YSLTMALATGARKYGVLLKYPAPVTSLKPRPDGTWDVETPQGSVRANRIVNAAGFWAREV 248
             L  AL T     GV +    PV  L  + +G W V     S+ A+ +++A       +
Sbjct: 240 EMLPQALETHLTSRGVSVLRGQPVCGLSLQAEGRWKVSLRDSSLEADHVISAIPA--SVL 297

Query: 249 GKMIGLDHPLIPVQHQYVVTSTIPEVKALKRELPVLRDLEGSYYLRQERDGLLFGPYESQ 308
            +++  +   +      +              + V+       +L  +  G L    E  
Sbjct: 298 SELLPAEAAPLARALSAI----------TAVSVAVVNLQYQGAHLPVQGFGHLVPSSEDP 347

Query: 309 EKMKLQASWVA----HGVPPGFGKELFESD 334
             + +    VA     G PPG    +    
Sbjct: 348 GVLGIVYDSVAFPEQDGSPPGLRVTVMLGG 377



 Score = 30.9 bits (68), Expect = 2.2,   Method: Composition-based stats.
 Identities = 11/37 (29%), Positives = 21/37 (56%), Gaps = 2/37 (5%)

Query: 45 TVIIGGGCVGVSLAYHLAKAGM--RDVVLLEKSELTA 79
           V++GGG  G++ +YHL++A    + V++     L  
Sbjct: 11 VVVLGGGISGLAASYHLSRAPCPPKVVLVESSERLGG 47


>4NTC-A nrPDB
          Length = 335

 Score = 32.5 bits (72), Expect = 0.87,   Method: Composition-based stats.
 Identities = 13/62 (20%), Positives = 24/62 (38%), Gaps = 1/62 (1%)

Query: 44  ETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKIHY 103
           + +IIG G  G+S A  LA+  +   V+ +        T H   +  + H      +   
Sbjct: 16  DVLIIGAGPAGLSTATGLARQ-LHTAVVFDSGVYRNAKTQHMHNVLGWDHRNPAELRAAG 74

Query: 104 DS 105
            +
Sbjct: 75  RA 76


>5Z70-A nrPDB
          Length = 605

 Score = 32.1 bits (71), Expect = 0.95,   Method: Composition-based stats.
 Identities = 15/79 (18%), Positives = 29/79 (36%), Gaps = 5/79 (6%)

Query: 47  IIGGGCVGVSLAYHLAKAGM---RDVVLLEKSELTAGS--TWHAAGLTTYFHPGINLKKI 101
           IIG G  G++ A++L + G    +D+ +L+      GS      A        G  +   
Sbjct: 9   IIGSGIAGLASAFYLIRDGRMKGQDITILDAVGTPGGSLDGSGNAEDGYLIRGGREMNWN 68

Query: 102 HYDSIKLYERLEEETGQVV 120
           +     L++ +        
Sbjct: 69  YDHFWDLFQDIPALEYPSP 87


>6C6P-A nrPDB
          Length = 458

 Score = 32.1 bits (71), Expect = 0.96,   Method: Composition-based stats.
 Identities = 10/30 (33%), Positives = 18/30 (60%)

Query: 44 ETVIIGGGCVGVSLAYHLAKAGMRDVVLLE 73
          E +I+G G +G +LA  L++ G +  V+  
Sbjct: 9  EVIIVGAGVLGSALAAVLSRDGRKVTVIER 38


>3Q6J-A nrPDB
          Length = 523

 Score = 32.1 bits (71), Expect = 0.97,   Method: Composition-based stats.
 Identities = 16/85 (18%), Positives = 33/85 (38%), Gaps = 1/85 (1%)

Query: 41  DRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKK 100
              + + IGGG  G   + +L   G R +++ ++     GS  H A +  +       + 
Sbjct: 42  REYDAIFIGGGAAGRFGSAYLRAMGGRQLIV-DRWPFLGGSCPHNACVPHHLFSDCAAEL 100

Query: 101 IHYDSIKLYERLEEETGQVVGFHQP 125
           +   +        + T +VVG  + 
Sbjct: 101 MLARTFSGQYWFPDMTEKVVGIKEV 125


>6QE4-A nrPDB
          Length = 327

 Score = 32.1 bits (71), Expect = 0.99,   Method: Composition-based stats.
 Identities = 50/309 (16%), Positives = 88/309 (28%), Gaps = 75/309 (24%)

Query: 533 FNIKGQDSTQLLDHLCANVIPKVGFTN----------ISHMLTPRGRVYAELTVSHQSPG 582
             ++G D+   L  L  N +P                 +H L  +GR   ++ +      
Sbjct: 30  LRVRGPDAAPFLLGLLTNELPLPSPAAAGAPPAARAGYAHFLNVQGRTLYDVILYGLQEH 89

Query: 583 E----FLLITGSGSELHDLRWIEEAAVRGGYDVEIRNITDELGVLGVAGPYARRVLQKLT 638
                FLL   S  +    + +    +R    VE      EL V  V             
Sbjct: 90  SEVSGFLLECDSSVQGALQKHLALYRIRRKVTVE---PHPELRVWAV------------- 133

Query: 639 SEDLSDDVFKFLQTKSLKISDIPVTAIRISYTGELGWEL--------YHRREDSAALYE- 689
              L             + +      IR   T  +GW L                 L++ 
Sbjct: 134 ---LPSSPEACGAASLQERAGAAAILIRDPRTARMGWRLLTQDEGPALVPGGRLGDLWDY 190

Query: 690 --RIMNAGQEEGIDNFGTYALNALRLEKAFRAWGSEMNCDTNPLEAGLDYFIKLNKPADF 747
                  G  EG+ +       AL LE                   G+ +         +
Sbjct: 191 HQHRYLQGVPEGVRDLPPGV--ALPLESNLA------------FMNGVSFT-----KGCY 231

Query: 748 TGKQALKQIKAKGL-KRRLVCLT----LATDDVDPEGNESVWYKGKVIGNTTSGSYSYSI 802
            G++   +    G+ ++RL  +     L T  + P G   +   G+ +G   +G      
Sbjct: 232 IGQELTARTHHMGVIRKRLFPVRFLDPLPTSGITP-GATVLTASGQTVGKFRAG------ 284

Query: 803 QKSLAFAYV 811
           Q ++  A +
Sbjct: 285 QGNVGLALL 293


>4YNU-A nrPDB
          Length = 571

 Score = 32.1 bits (71), Expect = 1.0,   Method: Composition-based stats.
 Identities = 10/34 (29%), Positives = 19/34 (55%)

Query: 42 RAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKS 75
            + +++GGG  G+ +A  L++     V+LLE  
Sbjct: 5  TYDYIVVGGGTSGLVVANRLSENPDVSVLLLEAG 38


>3LZX-A nrPDB
          Length = 332

 Score = 32.1 bits (71), Expect = 1.0,   Method: Composition-based stats.
 Identities = 21/110 (19%), Positives = 35/110 (31%), Gaps = 16/110 (14%)

Query: 38  EWKDRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAGLTTYFHPGIN 97
           E     +  IIGGG VG+  A++         ++    +L    +        Y   G  
Sbjct: 3   EDTKVYDITIIGGGPVGLFTAFYGGMRQASVKIIESLPQLGGQLSALYPEKYIYDVAGFP 62

Query: 98  LKKIHYDSIKLYERLEEET---GQVVGFHQP---------GSIRLATTPE 135
                  + +L   L+E+     Q +   Q          G  +L T  E
Sbjct: 63  KI----RAQELINNLKEQMAKFDQTICLEQAVESVEKQADGVFKLVTNEE 108


>4F5M-A nrPDB
          Length = 406

 Score = 32.1 bits (71), Expect = 1.1,   Method: Composition-based stats.
 Identities = 25/111 (22%), Positives = 39/111 (35%), Gaps = 7/111 (6%)

Query: 49  GGGCVGVSLAYHLAKA-GMRDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKIHYDSIK 107
           GG       A  LAK   ++ V +   S     S +++AGL    +   + +    D   
Sbjct: 112 GGTGALRVAADFLAKNTSVKRVWVSNPSWPNHKSVFNSAGLEVREYAYYDAENHTLDFDA 171

Query: 108 LYERLEE-ETGQVVGFHQPGSIRLATTPERVDEFKYQMTRTNWHATEQYII 157
           L   L E + G VV FH          P  +D    Q       + E+  +
Sbjct: 172 LINSLNEAQAGDVVLFH-----GCCHNPTGIDPTLEQWQTLAQLSVEKGWL 217


>2ZBW-A nrPDB
          Length = 335

 Score = 32.1 bits (71), Expect = 1.2,   Method: Composition-based stats.
 Identities = 19/106 (17%), Positives = 33/106 (31%), Gaps = 6/106 (5%)

Query: 41  DRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKK 100
           D  + +I+G G  G+   +++   G+    +    E     T        Y   G     
Sbjct: 4   DHTDVLIVGAGPTGLFAGFYVGMRGLSFRFVDPLPEPGGQLTALYPEKYIYDVAGFPKV- 62

Query: 101 IHYDSIKLYERLEEETGQVVGFHQPGSIRLATTPERVDEFKYQMTR 146
               +  L + L E+       +  G    A T ER  +     T 
Sbjct: 63  ---YAKDLVKGLVEQVAPFNPVYSLG--ERAETLEREGDLFKVTTS 103


>1I8T-A nrPDB
          Length = 367

 Score = 31.7 bits (70), Expect = 1.3,   Method: Composition-based stats.
 Identities = 8/38 (21%), Positives = 18/38 (47%)

Query: 43 AETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAG 80
           + +I+G G  G   A  L K   + +V+ +++ +   
Sbjct: 2  YDYIIVGSGLFGAVCANELKKLNKKVLVIEKRNHIGGN 39


>4MO2-B nrPDB
          Length = 368

 Score = 31.7 bits (70), Expect = 1.3,   Method: Composition-based stats.
 Identities = 8/38 (21%), Positives = 17/38 (44%)

Query: 43 AETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAG 80
           + +I+G G  G   AY   + G   +V+ ++  +   
Sbjct: 2  YDYLIVGSGLFGSIFAYEATEKGYTCLVVEQREHIGGN 39


>6GAS-A nrPDB
          Length = 331

 Score = 31.7 bits (70), Expect = 1.3,   Method: Composition-based stats.
 Identities = 14/79 (17%), Positives = 28/79 (35%), Gaps = 4/79 (5%)

Query: 37  PEWKDRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAGLTTYFHPGI 96
            E +   +  IIGGG  G+  A++         ++    +L    +        Y   G 
Sbjct: 4   AENQKVYDITIIGGGPTGLFTAFYGGMRQASVKIIESLPQLGGQLSALYPEKYIYDVAGF 63

Query: 97  NLKKIHYDSIKLYERLEEE 115
                   + +L + L+E+
Sbjct: 64  PKV----RAQELVDNLKEQ 78


>1MAF-H nrPDB
          Length = 373

 Score = 31.7 bits (70), Expect = 1.4,   Method: Composition-based stats.
 Identities = 17/98 (17%), Positives = 26/98 (26%), Gaps = 3/98 (3%)

Query: 362 NGPITYSPDILPMV---GPHQGVRNYWVAIGFGYGIIHAGGVGKYLSDWILHGEPPFDLI 418
           N     +      +     H  +   WV       I+     G   +    H    F L 
Sbjct: 24  NDEAPGADGRRSYINLPAHHSAIIQQWVLDAGSGSILGHVNGGFLPNPVAAHSGSEFALA 83

Query: 419 ELDPNRYGKWTTTQYTEAKARESYGFNNIVGYPKEERF 456
               +R  K   T Y E     ++     +  P   RF
Sbjct: 84  STSFSRIAKGKRTDYVEVFDPVTFLPIADIELPDAPRF 121


>3RED-A nrPDB
          Length = 521

 Score = 31.7 bits (70), Expect = 1.5,   Method: Composition-based stats.
 Identities = 14/42 (33%), Positives = 22/42 (52%), Gaps = 2/42 (4%)

Query: 38 EWKDRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTA 79
          E +   + VI+GGG  G  LA  L++     V++LE+  L  
Sbjct: 22 ELEGSYDYVIVGGGTSGCPLAATLSEK--YKVLVLERGTLPT 61


>5BR7-A nrPDB
          Length = 393

 Score = 31.7 bits (70), Expect = 1.6,   Method: Composition-based stats.
 Identities = 15/109 (13%), Positives = 43/109 (39%), Gaps = 7/109 (6%)

Query: 43  AETVIIGGGCVGVSLAYHLAKA-GMRDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKI 101
            + +++G G  G+++A   A   G + +++ ++S L   +   A   T            
Sbjct: 4   FDLIVVGSGLFGLTVAERAASQLGKKVLIVEKRSHLGGNAYSEAEPETGIEIHKYGAHLF 63

Query: 102 HYDSIKLYERLEEET------GQVVGFHQPGSIRLATTPERVDEFKYQM 144
           H  + ++++ + + T       +V   H   + +       +++F  + 
Sbjct: 64  HTSNKRVWDYVNQFTAFTGYQHRVFAMHNGTAYQFPMGLGLINQFFGRY 112


>1DOD-A nrPDB
          Length = 394

 Score = 31.3 bits (69), Expect = 1.7,   Method: Composition-based stats.
 Identities = 12/35 (34%), Positives = 20/35 (57%)

Query: 42 RAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSE 76
          + +  IIG G  G+ L   L KAG+ +V+L  ++ 
Sbjct: 2  KTQVAIIGAGPSGLLLGQLLHKAGIDNVILERQTP 36


>2D3L-A nrPDB
          Length = 485

 Score = 31.3 bits (69), Expect = 1.7,   Method: Composition-based stats.
 Identities = 19/109 (17%), Positives = 31/109 (28%), Gaps = 9/109 (8%)

Query: 470 ILESKCSMGFHAGWEQP----HWFYKPGQDTQYRPSFRRTNWFRPVGSEYKQVMQRVGVI 525
              +  +M  +  W  P    HW       +  +       W  P      Q     G  
Sbjct: 2   HNGTNGTMMQYFEWYLPNDGNHWNRLNSDASNLKSKGITAVWIPPAWKGASQNDVGYGAY 61

Query: 526 DLSPFGKFNIKGQDSTQL-----LDHLCANVIPKVGFTNISHMLTPRGR 569
           DL   G+FN KG   T+      L     ++           ++  +G 
Sbjct: 62  DLYDLGEFNQKGTVRTKYGTRSQLQAAVTSLKNNGIQVYGDVVMNHKGG 110


>1ZDL-A nrPDB
          Length = 517

 Score = 31.3 bits (69), Expect = 1.8,   Method: Composition-based stats.
 Identities = 12/49 (24%), Positives = 21/49 (42%)

Query: 40 KDRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAGL 88
          +   + ++IGGG  G++ A   A+ G +  V         G+ W   G 
Sbjct: 30 QQSFDLLVIGGGSGGLACAKEAAQLGKKVAVADYVEPSPRGTKWGLGGT 78


>2HQM-A nrPDB
          Length = 479

 Score = 31.3 bits (69), Expect = 1.8,   Method: Composition-based stats.
 Identities = 40/214 (18%), Positives = 72/214 (33%), Gaps = 25/214 (11%)

Query: 41  DRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAG--STWHAAGLTTYFHPGINL 98
              + ++IGGG  GV+ A   A  G + +++  K+ L     +         ++   +  
Sbjct: 10  KHYDYLVIGGGSGGVASARRAASYGAKTLLVEAKA-LGGTCVNVGCVPKKVMWYASDLAT 68

Query: 99  KKIHYDSIKLYERLEEETGQVVGFHQPGSIRLATTPERVDEFKYQMTR--TNWHATEQYI 156
           +  H +   LY+ L  +   +  F+ P             EFK +        +   Q  
Sbjct: 69  RVSHANEYGLYQNLPLDKEHLT-FNWP-------------EFKQKRDAYVHRLNGIYQKN 114

Query: 157 IEPEKIHELFPLLNMDKILAGLYNPGDGHIDPYSLTMALATGARKYGVLLKYPAPVTSLK 216
           +E EK+  +F     +K         D   + YS    L   A     +     P   L 
Sbjct: 115 LEKEKVDVVFGWARFNKDGNVEVQKRDNTTEVYSANHILV--ATGGKAIFPENIPGFELG 172

Query: 217 PRPDGTWDVETPQGSVRANRIVNAAGFWAREVGK 250
              DG + +E          +V  AG+   E+  
Sbjct: 173 TDSDGFFRLEEQ----PKKVVVVGAGYIGIELAG 202


>4UDQ-A nrPDB
          Length = 531

 Score = 31.3 bits (69), Expect = 1.9,   Method: Composition-based stats.
 Identities = 12/33 (36%), Positives = 17/33 (51%)

Query: 43 AETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKS 75
           + VI+GGG  G  LA  L+      V+L+E  
Sbjct: 6  FDYVIVGGGTAGSVLANRLSARPENRVLLIEAG 38


>4AP1-A nrPDB
          Length = 549

 Score = 31.3 bits (69), Expect = 1.9,   Method: Composition-based stats.
 Identities = 16/112 (14%), Positives = 33/112 (29%), Gaps = 7/112 (6%)

Query: 34  PSPPEWKDRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAGLTTYFH 93
           P         + V++G G  G+   +     G+        S +     W+      Y  
Sbjct: 13  PDATTGTTSYDVVVVGAGIAGLYAIHRFRSQGLTVRAFEAASGVGGVWYWN-----RYPG 67

Query: 94  PGINLKKIHYDSIKLYERLEEETGQVVGF-HQPGSIRLATTPERVDEFKYQM 144
              +++ I   S      LE+E      +  QP  +          + +  +
Sbjct: 68  ARCDVESI-DYSYSFSPELEQEWNWSEKYATQPEILAYLEHVADRFDLRRDI 118


>1CSN-A nrPDB
          Length = 298

 Score = 31.3 bits (69), Expect = 2.0,   Method: Composition-based stats.
 Identities = 9/37 (24%), Positives = 21/37 (56%)

Query: 37 PEWKDRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLE 73
          P+ +D   T  +  GC G+   Y+  + G+ +V++++
Sbjct: 50 PQLRDEYRTYKLLAGCTGIPNVYYFGQEGLHNVLVID 86


>3RP7-A nrPDB
          Length = 407

 Score = 30.9 bits (68), Expect = 2.2,   Method: Composition-based stats.
 Identities = 40/257 (15%), Positives = 68/257 (26%), Gaps = 25/257 (9%)

Query: 211 PVTSLKPRPDGTWDVETPQGSVRANRIVNAAGFWAREVGKMIGLDHPLIPVQHQYVVTS- 269
            VT  +   DG     T   S   + ++ A G  +     ++G   P             
Sbjct: 147 RVTRCEEDADGVTVWFTDGSSASGDLLIAADGSHSALRPWVLGFT-PQRRYAGYVNWNGL 205

Query: 270 -TIPEVKALKRELPVLRDLEGSYYLRQERDGLLF---------GPYESQEKMKLQASWVA 319
             I E  A   +            L     G  +         G  E ++ ++   S   
Sbjct: 206 VEIDEALAPGDQWTTFVGEGKRVSLMPVSAGRFYFFFDVPLPAGLAEDRDTLRADLSRYF 265

Query: 320 HGVPPGFGKELFESDLDRITEHVEAAMEMVPVLKKADIINIVNGPITYSPDILPMVGPHQ 379
            G  P   K +   D           +E    L +  +  + +   + +PDI    G   
Sbjct: 266 AGWAPPVQKLIAALDPQTTNRIEIHDIEPFSRLVRGRVALLGDAGHSTTPDIGQG-GCAA 324

Query: 380 GVRNYWVAIGFGYGIIHAGGVGKYLS-------DWILHGEPPFDLIELDPNRYGKWTTTQ 432
                 +   F      A  + +Y +       D +L           D         T+
Sbjct: 325 MEDAVVLGAVFRQTRDIAAALREYEAQRCDRVRDLVLKAR-----KRCDITHGKDMQLTE 379

Query: 433 YTEAKARESYGFNNIVG 449
               + RE  G   I G
Sbjct: 380 AWYQELREETGERIING 396


>3GDN-A nrPDB
          Length = 521

 Score = 30.9 bits (68), Expect = 2.3,   Method: Composition-based stats.
 Identities = 14/42 (33%), Positives = 22/42 (52%), Gaps = 2/42 (4%)

Query: 38 EWKDRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTA 79
          E +   + VI+GGG  G  LA  L++     V++LE+  L  
Sbjct: 22 ELEGSYDYVIVGGGTSGCPLAATLSEK--YKVLVLERGSLPT 61


>2X3N-A nrPDB
          Length = 399

 Score = 30.9 bits (68), Expect = 2.3,   Method: Composition-based stats.
 Identities = 46/286 (16%), Positives = 84/286 (29%), Gaps = 55/286 (19%)

Query: 44  ETVIIGGGCVGVSLAYHLAKAGMRDVVLL---EKSELTAGSTWHAAGLTTYFHPGINLKK 100
           + +I G G  G  LAY L + G R VV+     +  +        AG+      G+ L +
Sbjct: 8   DVLINGCGIGGAMLAYLLGRQGHRVVVVEQARRERAINGADLLKPAGIRVVEAAGL-LAE 66

Query: 101 IHYDSIKLYERLEEETGQVVGFHQPGSIRLATTPERVDEFKYQMTRTNWHATEQYIIEPE 160
           +     ++   L  E                       E       ++  A   +I+ P 
Sbjct: 67  VTRRGGRVRHEL--EVYHD------------------GELLRYFNYSSVDARGYFILMP- 105

Query: 161 KIHELFPLLNMDKILAGLYNPGDGHIDPYSLTMALATGARKYGVLLKYPAPVTSLKPRPD 220
              E    L ++KI                          +  V + +   + +++    
Sbjct: 106 --CESLRRLVLEKIDG------------------------EATVEMLFETRIEAVQRDER 139

Query: 221 GTWD-VETPQGSVRANRIVNAAGFWAREV-GKMIGLDHPLIPVQHQYVVTSTIPEVKALK 278
              D V    G V   R+V  A   A  V  +++ +D    P     +V +        +
Sbjct: 140 HAIDQVRLNDGRVLRPRVVVGADGIASYVRRRLLDIDVERRPYPSPMLVGTFALAPCVAE 199

Query: 279 RELPVLRDLEGSYYLRQER--DGLLFGPYESQEKMKLQASWVAHGV 322
           R    +    G  Y          L   +  +E  +L A      +
Sbjct: 200 RNRLYVDSQGGLAYFYPIGFDRARLVVSFPREEARELMADTRGESL 245


>3B40-A nrPDB
          Length = 417

 Score = 30.2 bits (66), Expect = 3.8,   Method: Composition-based stats.
 Identities = 23/151 (15%), Positives = 53/151 (35%), Gaps = 16/151 (10%)

Query: 60  HLAKAGMRDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKIHYDSIKLYERLEEETGQV 119
            ++   +  V  L ++ + A  +   A +    +   +  ++  DS  +         QV
Sbjct: 213 QMSTKALEQVAALSRAPIVASHSAPRALVDIKRNLSDHEMQLIKDSGGVI--------QV 264

Query: 120 VGFHQPGSIRLATTPERVDEFKYQMTRTNWHATEQYIIEPEKIHELFPLLNMDKILAGLY 179
           VGF          T +++D  + +         +  ++  + I  ++P     +  + LY
Sbjct: 265 VGFPAYLRPLSKPTLDKLDALRARFDLPPLEGLDYALMPGDPIITIWPEQRFGEYASALY 324

Query: 180 -----NPGDGHIDPYSLTMALATGARKYGVL 205
                 P  G  +   L  A+    +K G+ 
Sbjct: 325 GILEEEPKAGLKE---LVDAIDYTVKKVGID 352


>4HA6-A nrPDB
          Length = 508

 Score = 30.2 bits (66), Expect = 4.0,   Method: Composition-based stats.
 Identities = 35/213 (16%), Positives = 60/213 (28%), Gaps = 28/213 (13%)

Query: 44  ETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAG----STWHAAGLTTYFHPG--IN 97
           + VI+GGG  G  LA  L++     V+L+E  E        +      L    +      
Sbjct: 3   DIVIVGGGSAGSLLAARLSEDPDSRVLLIEAGEEPTDPDIWNPAAWPALQGRSYDWDYRT 62

Query: 98  LKKIHYDSIKLYERLEEETGQVVGFHQPGSIRLATTPERVDEFKYQMTRT--NWHATEQY 155
             +        +       G     H  G +R         +F+  +  +       +  
Sbjct: 63  EAQAGTAGRAHHWARGRLIGGSSCLHAMGYMR-----GHPSDFQAWVDASGDRRWGWD-E 116

Query: 156 IIEPEKIHELFPLLNMDKILAG----LYNPGDGHIDPYSLTMALATGARKYGVLLKYPAP 211
           ++   +  E  PL        G    ++ P D   +   L  A        G+       
Sbjct: 117 LLPVFQAIEDHPLGGDGIHGKGGPLPIHLPAD---EVSPLARAFIEAGASLGLPRLE--- 170

Query: 212 VTSLKPRPDGTWDVETPQGSVRANRIVNAAGFW 244
                        V     ++R  R V AA  W
Sbjct: 171 ----GHNSGEMIGVTPNSLNIRDGRRVTAADAW 199


>2EPJ-A nrPDB
          Length = 434

 Score = 29.4 bits (64), Expect = 7.5,   Method: Composition-based stats.
 Identities = 40/223 (17%), Positives = 70/223 (31%), Gaps = 30/223 (13%)

Query: 171 MDKILAGLYNP---GDGHIDPYS-LTMALATGARKYGVLLKYPAPVTSLKPRPDGTWDVE 226
            D+I   +  P     G I P      AL   +R+ G LL     VT  +   +G     
Sbjct: 201 GDRIAGVIVEPVIANAGVIPPRREFLAALQRLSRESGALLILDEVVTGFRLGLEGAQGYF 260

Query: 227 TPQGSVRANRIVNAAGFWAREVGKMIGLDHPLIPVQHQYVVTSTIPEVKALKRELPVLRD 286
             +G +               +GK+IG   P+  V     V S +        +  V   
Sbjct: 261 NIEGDII-------------VLGKIIGGGFPVGAVAGSREVMSLLTP------QGKVFNA 301

Query: 287 LEGSYYLRQERDGLLFGPYESQEKMKLQASWVAHGVPPGFGKELFESDLDRITEHVEAAM 346
              + +      GL       +E +   +   A  +     + L  + L      VE+ M
Sbjct: 302 GTFNAHPITMAAGLATLKALEEEPVYSVSREAAKALEEAASEVLDRTGLPYTINRVESMM 361

Query: 347 EMVPVLKKADIINIVNGPITYSPDILPMVGPHQG--VRNYWVA 387
           ++   +++       N       D    V  H+    R  ++A
Sbjct: 362 QLFIGVEEVS-----NAAQARKADKKFYVKLHEEMLRRGVFIA 399


>6AH0-2 nrPDB
          Length = 895

 Score = 29.0 bits (63), Expect = 8.2,   Method: Composition-based stats.
 Identities = 11/28 (39%), Positives = 16/28 (57%), Gaps = 1/28 (3%)

Query: 460 PTQRVSGLYKILESKCSMGFHA-GWEQP 486
           P  ++ GL   +   CS G+HA GW +P
Sbjct: 646 PNLKIPGLNSPIPESCSFGYHAGGWGKP 673


>5W1J-A nrPDB
          Length = 584

 Score = 29.0 bits (63), Expect = 8.5,   Method: Composition-based stats.
 Identities = 19/51 (37%), Positives = 26/51 (50%)

Query: 38  EWKDRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAGL 88
           E K   + VIIGGG  G++LA   AK+G +  +L        G+TW   G 
Sbjct: 99  EMKYDYDMVIIGGGSGGLALAKESAKSGAKVALLDFVVPTPMGTTWGLGGT 149


  Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta
    Posted date:  Jan 3, 2023  9:05 PM
  Number of letters in database: 10,336,785
  Number of sequences in database:  36,641
  
Lambda     K      H
   0.306    0.122    0.292 

Lambda     K      H
   0.267   0.0373    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,633,269
Number of Sequences: 36641
Number of extensions: 1157358
Number of successful extensions: 3820
Number of sequences better than 10.0: 184
Number of HSP's better than 10.0 without gapping: 173
Number of HSP's successfully gapped in prelim test: 85
Number of HSP's that attempted gapping in prelim test: 3424
Number of HSP's gapped (non-prelim): 310
length of query: 857
length of database: 10,336,785
effective HSP length: 105
effective length of query: 752
effective length of database: 6,489,480
effective search space: 4880088960
effective search space used: 4880088960
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.2 bits)
S2: 63 (29.0 bits)