BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q63342 (857 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 4P9S-A nrPDB 1717 0.0 5L46-A nrPDB 1603 0.0 1PJ5-A nrPDB 351 9e-97 1YX2-A nrPDB 164 2e-40 1WOR-A nrPDB 150 3e-36 1V5V-A nrPDB 125 1e-28 1VRQ-A nrPDB 117 2e-26 2GAG-A nrPDB 113 3e-25 3A8J-A nrPDB 94 2e-19 1WSR-A nrPDB 89 1e-17 3GIR-A nrPDB 88 2e-17 2GAG-B nrPDB 77 3e-14 3TFJ-A nrPDB 71 2e-12 1NG3-A nrPDB 68 2e-11 3SM8-A nrPDB 66 5e-11 4YSH-A nrPDB 64 3e-10 3AD9-B nrPDB 55 2e-07 3BHF-A nrPDB 45 1e-04 1ZOV-A nrPDB 43 5e-04 2UZZ-A nrPDB 38 0.022 2GAH-C nrPDB 37 0.041 1KNR-A nrPDB 35 0.16 5KXJ-A nrPDB 34 0.35 4IV9-A nrPDB 33 0.42 4C5O-A nrPDB 33 0.44 5MOG-A nrPDB 33 0.46 6QZO-A nrPDB 32 0.80 3L1R-A nrPDB 32 0.85 3S2F-A nrPDB 32 0.97 4UIR-A nrPDB 32 1.1 2JB2-A nrPDB 32 1.7 3KVE-A nrPDB 31 1.9 1F8S-A nrPDB 31 2.1 3RHA-A nrPDB 31 2.4 4Y4M-A nrPDB 31 2.7 1VRQ-C nrPDB 31 2.9 4IVM-B nrPDB 30 3.1 4K28-A nrPDB 30 3.2 3ATQ-A nrPDB 30 3.7 2IVE-A nrPDB 30 4.4 3RO8-A nrPDB 30 5.1 1RP0-A nrPDB 30 5.3 5JMD-A nrPDB 30 5.7 5Z9A-A nrPDB 30 5.9 3R9U-A nrPDB 29 7.2 1REO-A nrPDB 29 7.2 4N9X-A nrPDB 29 8.8 6BRD-A nrPDB 29 9.6 >4P9S-A nrPDB Length = 848 Score = 1717 bits (4447), Expect = 0.0, Method: Compositional matrix adjust. Identities = 830/836 (99%), Positives = 833/836 (99%) Query: 22 SSAGLREGQESPPSPPEWKDRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGS 81 SSAGLREGQESPPSPPEWKDRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGS Sbjct: 3 SSAGLREGQESPPSPPEWKDRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGS 62 Query: 82 TWHAAGLTTYFHPGINLKKIHYDSIKLYERLEEETGQVVGFHQPGSIRLATTPERVDEFK 141 TWHAAGLTTYFHPGINLKKIHYDSIKLYERLEEETGQVVGFHQPGSIRLATTPERVDEFK Sbjct: 63 TWHAAGLTTYFHPGINLKKIHYDSIKLYERLEEETGQVVGFHQPGSIRLATTPERVDEFK 122 Query: 142 YQMTRTNWHATEQYIIEPEKIHELFPLLNMDKILAGLYNPGDGHIDPYSLTMALATGARK 201 YQMTRTNWHATEQYIIEPEKIHELFPLLNMDKILAGLYNPGDGHIDPYSLTMALATGARK Sbjct: 123 YQMTRTNWHATEQYIIEPEKIHELFPLLNMDKILAGLYNPGDGHIDPYSLTMALATGARK 182 Query: 202 YGVLLKYPAPVTSLKPRPDGTWDVETPQGSVRANRIVNAAGFWAREVGKMIGLDHPLIPV 261 YG LLKYPAPVTSLKPRPDGTWDVETPQGSVRANRIVNAAGFWAREVGKMIGLDHPLIPV Sbjct: 183 YGALLKYPAPVTSLKPRPDGTWDVETPQGSVRANRIVNAAGFWAREVGKMIGLDHPLIPV 242 Query: 262 QHQYVVTSTIPEVKALKRELPVLRDLEGSYYLRQERDGLLFGPYESQEKMKLQASWVAHG 321 QHQYV+TSTIPEVKALKRELPVLRDLEGSYYLRQERDGLLFGPYESQEKMKLQASWVAHG Sbjct: 243 QHQYVITSTIPEVKALKRELPVLRDLEGSYYLRQERDGLLFGPYESQEKMKLQASWVAHG 302 Query: 322 VPPGFGKELFESDLDRITEHVEAAMEMVPVLKKADIINIVNGPITYSPDILPMVGPHQGV 381 VPPGFGKELFESDLDRITEHVEAAMEMVPVLKKADIINIVNGPITYSPDILPMVGPHQGV Sbjct: 303 VPPGFGKELFESDLDRITEHVEAAMEMVPVLKKADIINIVNGPITYSPDILPMVGPHQGV 362 Query: 382 RNYWVAIGFGYGIIHAGGVGKYLSDWILHGEPPFDLIELDPNRYGKWTTTQYTEAKARES 441 RNYWVAIGFGYGIIHAGGVG YLSDWILHGEPPFDLIELDPNRYGKWTTTQYTEAKARES Sbjct: 363 RNYWVAIGFGYGIIHAGGVGTYLSDWILHGEPPFDLIELDPNRYGKWTTTQYTEAKARES 422 Query: 442 YGFNNIVGYPKEERFAGRPTQRVSGLYKILESKCSMGFHAGWEQPHWFYKPGQDTQYRPS 501 YGFNNIVGYPKEERFAGRPTQRVSGLYKILESKCSMGFHAGWEQPHWFYKPGQDTQYRPS Sbjct: 423 YGFNNIVGYPKEERFAGRPTQRVSGLYKILESKCSMGFHAGWEQPHWFYKPGQDTQYRPS 482 Query: 502 FRRTNWFRPVGSEYKQVMQRVGVIDLSPFGKFNIKGQDSTQLLDHLCANVIPKVGFTNIS 561 FRRTNWF PVGSEYKQVMQRVGVIDLSPFGKFNIKGQDSTQLLDHLCANVIPKVGFTNIS Sbjct: 483 FRRTNWFEPVGSEYKQVMQRVGVIDLSPFGKFNIKGQDSTQLLDHLCANVIPKVGFTNIS 542 Query: 562 HMLTPRGRVYAELTVSHQSPGEFLLITGSGSELHDLRWIEEAAVRGGYDVEIRNITDELG 621 HMLTPRGRVYAELTVSHQSPGEFLLITGSGSELHDLRWIEEAAVRGGYDVEIRNITDELG Sbjct: 543 HMLTPRGRVYAELTVSHQSPGEFLLITGSGSELHDLRWIEEAAVRGGYDVEIRNITDELG 602 Query: 622 VLGVAGPYARRVLQKLTSEDLSDDVFKFLQTKSLKISDIPVTAIRISYTGELGWELYHRR 681 VLGVAGPYARRVLQKLTSEDLSDDVFKFLQTKSLKISDIPVTAIRISYTGELGWELYHRR Sbjct: 603 VLGVAGPYARRVLQKLTSEDLSDDVFKFLQTKSLKISDIPVTAIRISYTGELGWELYHRR 662 Query: 682 EDSAALYERIMNAGQEEGIDNFGTYALNALRLEKAFRAWGSEMNCDTNPLEAGLDYFIKL 741 EDSAALYERIMNAGQEEGIDNFGTYALNALRLEKAFRAWGSEMNCDTNPLEAGLDYFIKL Sbjct: 663 EDSAALYERIMNAGQEEGIDNFGTYALNALRLEKAFRAWGSEMNCDTNPLEAGLDYFIKL 722 Query: 742 NKPADFTGKQALKQIKAKGLKRRLVCLTLATDDVDPEGNESVWYKGKVIGNTTSGSYSYS 801 NKPA+FTGKQALKQIKAKGLKRRLVCLTLATD+VDPEGNESVWYKGKVIGNTTSGSYSYS Sbjct: 723 NKPANFTGKQALKQIKAKGLKRRLVCLTLATDNVDPEGNESVWYKGKVIGNTTSGSYSYS 782 Query: 802 IQKSLAFAYVPVELSEVGQQVEVELLGKNYPATIIQEPLVLTEPTRTRLQKDGRKS 857 IQKSLAFAYVPVELSEVGQQVEVELLGKNYPATIIQEPLVLTEPTRTRLQKDGRKS Sbjct: 783 IQKSLAFAYVPVELSEVGQQVEVELLGKNYPATIIQEPLVLTEPTRTRLQKDGRKS 838 >5L46-A nrPDB Length = 841 Score = 1603 bits (4150), Expect = 0.0, Method: Compositional matrix adjust. Identities = 769/832 (92%), Positives = 798/832 (95%), Gaps = 2/832 (0%) Query: 27 REGQESPPSPPE--WKDRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWH 84 REG+E PP E WKDRAETVIIGGGCVGVSLAYHLAKAGM+DVVLLEKSELTAGSTWH Sbjct: 5 REGEEKPPLSAETQWKDRAETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGSTWH 64 Query: 85 AAGLTTYFHPGINLKKIHYDSIKLYERLEEETGQVVGFHQPGSIRLATTPERVDEFKYQM 144 AAGLTTYFHPGINLKKIHYDSIKLYE+LEEETGQVVGFHQPGSIRLATTP RVDEFKYQM Sbjct: 65 AAGLTTYFHPGINLKKIHYDSIKLYEKLEEETGQVVGFHQPGSIRLATTPVRVDEFKYQM 124 Query: 145 TRTNWHATEQYIIEPEKIHELFPLLNMDKILAGLYNPGDGHIDPYSLTMALATGARKYGV 204 TRT WHATEQY+IEPEKI E+FPLLNM+K+LAGLYNPGDGHIDPYSLTMALA GARK G Sbjct: 125 TRTGWHATEQYLIEPEKIQEMFPLLNMNKVLAGLYNPGDGHIDPYSLTMALAAGARKCGA 184 Query: 205 LLKYPAPVTSLKPRPDGTWDVETPQGSVRANRIVNAAGFWAREVGKMIGLDHPLIPVQHQ 264 LLKYPAPVTSLK R DGTWDVETPQGS+RANRIVNAAGFWAREVGKMIGL+HPLIPVQHQ Sbjct: 185 LLKYPAPVTSLKARSDGTWDVETPQGSMRANRIVNAAGFWAREVGKMIGLEHPLIPVQHQ 244 Query: 265 YVVTSTIPEVKALKRELPVLRDLEGSYYLRQERDGLLFGPYESQEKMKLQASWVAHGVPP 324 YVVTSTIPEVKALKRELPVLRDLEGSYYLRQERDGLLFGPYESQEKMK+Q SWV +GVPP Sbjct: 245 YVVTSTIPEVKALKRELPVLRDLEGSYYLRQERDGLLFGPYESQEKMKVQDSWVTNGVPP 304 Query: 325 GFGKELFESDLDRITEHVEAAMEMVPVLKKADIINIVNGPITYSPDILPMVGPHQGVRNY 384 GFGKELFESDLDRI EH++AAMEMVPVLKKADIIN+VNGPITYSPDILPMVGPHQGVRNY Sbjct: 305 GFGKELFESDLDRIMEHIKAAMEMVPVLKKADIINVVNGPITYSPDILPMVGPHQGVRNY 364 Query: 385 WVAIGFGYGIIHAGGVGKYLSDWILHGEPPFDLIELDPNRYGKWTTTQYTEAKARESYGF 444 WVAIGFGYGIIHAGGVGKYLSDWILHGEPPFDLIELDPNRYGKWTTTQYTEAKARESYGF Sbjct: 365 WVAIGFGYGIIHAGGVGKYLSDWILHGEPPFDLIELDPNRYGKWTTTQYTEAKARESYGF 424 Query: 445 NNIVGYPKEERFAGRPTQRVSGLYKILESKCSMGFHAGWEQPHWFYKPGQDTQYRPSFRR 504 NNIVGYPKEERFAGRPTQRVSGLY+ LESKCSMGFHAGWEQPHWFYKPGQDTQYRPSFRR Sbjct: 425 NNIVGYPKEERFAGRPTQRVSGLYQRLESKCSMGFHAGWEQPHWFYKPGQDTQYRPSFRR 484 Query: 505 TNWFRPVGSEYKQVMQRVGVIDLSPFGKFNIKGQDSTQLLDHLCANVIPKVGFTNISHML 564 TNWF PVGSEYKQVMQRV V DLSPFGKFNIKGQDS +LLDHL ANVIPKVGFTNISHML Sbjct: 485 TNWFEPVGSEYKQVMQRVAVTDLSPFGKFNIKGQDSIRLLDHLFANVIPKVGFTNISHML 544 Query: 565 TPRGRVYAELTVSHQSPGEFLLITGSGSELHDLRWIEEAAVRGGYDVEIRNITDELGVLG 624 TP+GRVYAELTVSHQSPGEFLLITGSGSELHDLRWIEE AV+GGYDVEI+NITDELGVLG Sbjct: 545 TPKGRVYAELTVSHQSPGEFLLITGSGSELHDLRWIEEEAVKGGYDVEIKNITDELGVLG 604 Query: 625 VAGPYARRVLQKLTSEDLSDDVFKFLQTKSLKISDIPVTAIRISYTGELGWELYHRREDS 684 VAGP AR+VLQKLTSEDLSDDVFKFLQTKSLK+S+IPVTAIRISYTGELGWELYHRREDS Sbjct: 605 VAGPQARKVLQKLTSEDLSDDVFKFLQTKSLKVSNIPVTAIRISYTGELGWELYHRREDS 664 Query: 685 AALYERIMNAGQEEGIDNFGTYALNALRLEKAFRAWGSEMNCDTNPLEAGLDYFIKLNKP 744 ALY+ IMNAGQEEGIDNFGTYA+NALRLEKAFRAWG EMNCDTNPLEAGL+YF+KLNKP Sbjct: 665 VALYDAIMNAGQEEGIDNFGTYAMNALRLEKAFRAWGLEMNCDTNPLEAGLEYFVKLNKP 724 Query: 745 ADFTGKQALKQIKAKGLKRRLVCLTLATDDVDPEGNESVWYKGKVIGNTTSGSYSYSIQK 804 ADF GKQALKQIKAKGLKRRLVCLTLATDDVDPEGNES+WY GKV+GNTTSGSYSYSIQK Sbjct: 725 ADFIGKQALKQIKAKGLKRRLVCLTLATDDVDPEGNESIWYNGKVVGNTTSGSYSYSIQK 784 Query: 805 SLAFAYVPVELSEVGQQVEVELLGKNYPATIIQEPLVLTEPTRTRLQKDGRK 856 SLAFAYVPV+LSEVGQQVEVELLGKNYPA IIQEPLVLTEPTR RLQK G K Sbjct: 785 SLAFAYVPVQLSEVGQQVEVELLGKNYPAVIIQEPLVLTEPTRNRLQKKGGK 836 >1PJ5-A nrPDB Length = 830 Score = 351 bits (900), Expect = 9e-97, Method: Compositional matrix adjust. Identities = 247/839 (29%), Positives = 414/839 (49%), Gaps = 50/839 (5%) Query: 46 VIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELT--AGSTWHAAGLTTYFHPGINLKKIHY 103 VIIG G VG +LA L G ++ +L++ L GST HA GL +P + Sbjct: 8 VIIGAGIVGTNLADELVTRGWNNITVLDQGPLNMPGGSTSHAPGLVFQTNPSKTMASFAK 67 Query: 104 DSIKLYERLEEETGQVVGFHQPGSIRLATTPERVDEFKYQMTRTNWHATEQYIIEPEKIH 163 +++ L E+ V F+Q G + +ATT R+ + K ++ E ++ P + Sbjct: 68 YTVEKLLSLTED--GVSCFNQVGGLEVATTETRLADLKRKLGYAAAWGIEGRLLSPAECQ 125 Query: 164 ELFPLLNMDKILAGLYNPGDGHIDPYSLTMALATGARKYGVLLKYPAPVTSLKPRPDGTW 223 EL+PLL+ + IL GL+ P DG L GV + VT ++ Sbjct: 126 ELYPLLDGENILGGLHVPSDGLASAARAVQLLIKRTESAGVTYRGSTTVTGIEQSGGRVT 185 Query: 224 DVETPQGSVRANRIVNAAGFWAREVGKMIGLDHPLIPVQHQYVVTSTIPEVKALKRE--- 280 V+T G + A+ +V+ AGFW ++G MIG+ PL+P+ HQYV T+ +P + + Sbjct: 186 GVQTADGVIPADIVVSCAGFWGAKIGAMIGMAVPLLPLAHQYVKTTPVPAQQGRNDQPNG 245 Query: 281 --LPVLRDLEGSYYLRQERDGLLFGPYESQEKMKLQASWVAHGVPPGFGKELFESDLDRI 338 LP+LR + Y R+ D G Y + M + + P + S LD Sbjct: 246 ARLPILRHQDQDLYYREHGDRYGIGSY-AHRPMPVDVDTLGAYAPETVSEHHMPSRLDFT 304 Query: 339 TEHV----EAAMEMVPVLKKADIINIVNGPITYSPDILPMVGPHQGVRNYWVAIGFGYGI 394 E EA +++P L ++I + NG +++PD P++G + + ++VA + Sbjct: 305 LEDFLPAWEATKQLLPALADSEIEDGFNGIFSFTPDGGPLLGESKELDGFYVAEAVW--V 362 Query: 395 IHAGGVGKYLSDWILHGEPPFDLIELDPNRYGKWTTT-QYTEAKARESYGFNNIVGYPKE 453 H+ GV K +++ + G DL E D R+ T +Y +++++ V +P + Sbjct: 363 THSAGVAKAMAELLTTGRSETDLGECDITRFEDVQLTPEYVSETSQQNFVEIYDVLHPLQ 422 Query: 454 ERFAGRPTQRVSGLYKILESKCSMGFHAG-WEQPHWFYKPGQDTQYRPSFRRTNWFRPV- 511 R + R RVS + + + AG WE+P+WF + P+ W P Sbjct: 423 PRLSPR-NLRVSPFHARHKELGAFFLEAGGWERPYWFEANAALLKEMPA----EWLPPAR 477 Query: 512 ------------GSEYKQVMQRVGVIDLSPFGKFNIKGQDSTQLLDHLC-ANVIPKVGFT 558 +E + V + D++P + + G + +LL L A++ K G Sbjct: 478 DAWSGMFSSPIAAAEAWKTRTAVAMYDMTPLKRLEVSGPGALKLLQELTTADLAKKPGAV 537 Query: 559 NISHMLTPRGRVYAELTVSHQSPGEFLLITGSGSELHDLRWIEEAA---VRGGYD---VE 612 + +L G V +++TV+ S F L G+ + D + E AA + G V+ Sbjct: 538 TYTLLLDHAGGVRSDITVARLSEDTFQL--GANGNI-DTAYFERAARHQTQSGSATDWVQ 594 Query: 613 IRNITDELGVLGVAGPYARRVLQKLTSEDLSDDVFKFLQTKSLKISDIPVTAIRISYTGE 672 +R+ T +G+ GP AR ++ K++ +D ++D K+ + K++ I IPVTA+R+SY GE Sbjct: 595 VRDTTGGTCCIGLWGPLARDLVSKVSDDDFTNDGLKYFRAKNVVIGGIPVTAMRLSYVGE 654 Query: 673 LGWELYHRREDSAALYERIMNAGQEEGIDNFGTYALNALRLEKAFRAWGSEMNCDTNPLE 732 LGWELY ++ L++ + AGQ G+ G A ++LRLEK +R+WG++M + +P E Sbjct: 655 LGWELYTSADNGQRLWDALWQAGQPFGVIAAGRAAFSSLRLEKGYRSWGTDMTTEHDPFE 714 Query: 733 AGLDYFIKLNKPADFTGKQALKQIKAKGLKRRLVCLTLATDDVDPEGNESVWYKGKVIGN 792 AGL + +K+ K + F GK AL+ + RRL CLT+ G E V+YK + +G Sbjct: 715 AGLGFAVKMAKES-FIGKGALEGRTEEASARRLRCLTIDDGRSIVLGKEPVFYKEQAVGY 773 Query: 793 TTSGSYSYSIQKSLAFAYVPVELSEVGQQVEVELLGKNYPATIIQEPLVLTEPTRTRLQ 851 TS +Y Y++ K +A++Y+P +S VG V++E G+ AT+ ++PL +P TRL+ Sbjct: 774 VTSAAYGYTVAKPIAYSYLPGTVS-VGDSVDIEYFGRRITATVTEDPLY--DPKMTRLR 829 >1YX2-A nrPDB Length = 365 Score = 164 bits (414), Expect = 2e-40, Method: Compositional matrix adjust. Identities = 102/322 (31%), Positives = 165/322 (51%), Gaps = 9/322 (2%) Query: 508 FRPVGSEYKQVMQRVGVIDLSPFGKFNIKGQDSTQLLDHLCANVIPKV--GFTNISHMLT 565 F + E++ V G+ D+S G+ + G DS L L N + + G + M Sbjct: 33 FSSIKKEHEAVRTAAGLFDVSHMGEVEVSGNDSLSFLQRLMTNDVSALTPGRAQYTAMCY 92 Query: 566 PRGRVYAELTVSHQSPGEFLLITGSGSELHDLRWIEEAAVRGGYDVEIRNITDELGVLGV 625 P G +L + + +LL+ + + DL W++E A DV+I N +D++ +L V Sbjct: 93 PDGGTVDDLLIYQKGENRYLLVINASNIDKDLAWMKEHAAG---DVQIDNQSDQIALLAV 149 Query: 626 AGPYARRVLQKLTSEDLSD-DVFKFLQTKSLKISDIPVTAIRISYTGELGWELYHRREDS 684 GP A +L+ LT D+S F F+ IS R YTGE G+E+Y R +D+ Sbjct: 150 QGPKAEAILKNLTDADVSALKPFAFIDEAD--ISGRKALISRTGYTGEDGYEIYCRSDDA 207 Query: 685 AALYERIMNAGQEEGIDNFGTYALNALRLEKAFRAWGSEMNCDTNPLEAGLDYFIKLNKP 744 ++++I++AG G+ G A + LR E +G E+ D P+EAG+ + +K K Sbjct: 208 MHIWKKIIDAGDAYGLIPCGLGARDTLRFEANIPLYGQELTRDITPIEAGIGFAVKHKKE 267 Query: 745 ADFTGKQALKQIKAKGLKRRLVCLTLATDDVDPEGNESVWYKGKVIGNTTSGSYSYSIQK 804 +DF GK L + K G KR+LV L + + G E V+ GK +G T+G+ S ++ K Sbjct: 268 SDFFGKSVLSEQKENGAKRKLVGLEMIEKGIPRHGYE-VFQNGKSVGKVTTGTQSPTLGK 326 Query: 805 SLAFAYVPVELSEVGQQVEVEL 826 ++ A + E SE+G V+VE+ Sbjct: 327 NVGLALIDSETSEIGTVVDVEI 348 >1WOR-A nrPDB Length = 364 Score = 150 bits (378), Expect = 3e-36, Method: Compositional matrix adjust. Identities = 115/379 (30%), Positives = 191/379 (50%), Gaps = 35/379 (9%) Query: 469 KILESKCSMGFHAGWEQPHWFYKPGQDTQYRPSFRRTNWFRPVGSEYKQVMQRVGVIDLS 528 K +E M AGWE P ++ T+ F E V + VG+ D+S Sbjct: 9 KHVELGAKMVDFAGWEMPLYY---------------TSIFE----EVMAVRKSVGMFDVS 49 Query: 529 PFGKFNIKGQDSTQLLDHLCANVIPKV--GFTNISHMLTPRGRVYAELTVSHQSPGEFLL 586 G+F +KG ++ +D L N + G S M G + +L V SP E L+ Sbjct: 50 HMGEFLVKGPEAVSFIDFLITNDFSSLPDGKAIYSVMCNENGGIIDDLVVYKVSPDEALM 109 Query: 587 ITGSGSELHDLRWIEEAAVRGGYDVEIRNITDELGVLGVAGPYARRVLQKLTSEDLSDDV 646 + + + D WI+ + +DVE+ NI+D ++ GP A+ LQ+L ED +++ Sbjct: 110 VVNAANIEKDFNWIKSHS--KNFDVEVSNISDTTALIAFQGPKAQETLQELV-EDGLEEI 166 Query: 647 FKFLQTKSLKISDIPVTAIRISYTGELGWELYHRREDSAALYERIMNAGQEEGIDNFGTY 706 + KS+ ++ + R YTGE G+EL +++ +++ +MN ++ G Sbjct: 167 AYYSFRKSI-VAGVETLVSRTGYTGEDGFELMLEAKNAPKVWDALMNLLRKIDGRPAGLG 225 Query: 707 ALNALRLEKAFRAWGSEMNCDTNPLEAGLDYFIKLNKPADFTGKQALKQIKAKGLKRRLV 766 A + RLE + +G +M+ +TNP E GL + +KLNK DF GK+AL + K K ++R+LV Sbjct: 226 ARDVCRLEATYLLYGQDMDENTNPFEVGLSWVVKLNK--DFVGKEALLKAKEK-VERKLV 282 Query: 767 CLTLATDDVDPEGNESVWYKGKVIGNTTSGSYSYSIQKSLAFAYVPVELSEVGQQVEVEL 826 L L+ + +G E V G+ +G TSG++S ++ KS+A A V + ++G Q Sbjct: 283 ALELSGKRIARKGYE-VLKNGERVGEITSGNFSPTLGKSIALALVSKSV-KIGDQ----- 335 Query: 827 LGKNYPATIIQEPLVLTEP 845 LG +P + E LV+ +P Sbjct: 336 LGVVFPGGKLVEALVVKKP 354 >1V5V-A nrPDB Length = 401 Score = 125 bits (313), Expect = 1e-28, Method: Compositional matrix adjust. Identities = 103/366 (28%), Positives = 178/366 (48%), Gaps = 40/366 (10%) Query: 507 WFRPVGSEYKQVMQRVGVIDLSPFGKFNIKGQDSTQLLDHLCANVIPKVGFTNISH--ML 564 W+ + E+ V VG+ D+S G+ +G+D+ + L ++ N I K + ++ +L Sbjct: 32 WYSSIKEEHLAVRNAVGIFDVSHMGEIVFRGKDALKFLQYVTTNDISKPPAISGTYTLVL 91 Query: 565 TPRGRVYAELTVSHQSPGEFLLITGSGSELHDLRW-------IEEAAVRGGYDVEIRNIT 617 RG + E V + E+L+I S + W IE+ D+EI T Sbjct: 92 NERGAIKDETLVFNMGNNEYLMICDSDAFEKLYAWFTYLKRTIEQFT---KLDLEIELKT 148 Query: 618 DELGVLGVAGPYARRVLQKLTSEDLSDDVFKFLQTKSLKISDIPVTAIRISYTGELGWEL 677 ++ + V GP AR + + L D+++ + Q + +++ I + R YTGE G+E+ Sbjct: 149 YDIAMFAVQGPKARDLAKDLFGIDINE--MWWFQARWVELDGIKMLLSRSGYTGENGFEV 206 Query: 678 Y------------HRREDSAAL--YERIMNAGQEEGIDNFGTYALNALRLEKAFRAWGSE 723 Y R E AL +ERI+ G++ GI G A + LRLE + +G+E Sbjct: 207 YIEDANPYHPDESKRGEPEKALHVWERILEEGKKYGIKPCGLGARDTLRLEAGYTLYGNE 266 Query: 724 ------MNCDTN---PLEAGLDYFIKLNKPADFTGKQALKQIKAKGLKRRLVCLTLATDD 774 ++ D + PL+A L++ I +K DF GK AL + K +G+ R+LV + Sbjct: 267 TKELQLLSTDIDEVTPLQANLEFAIYWDK--DFIGKDALLKQKERGVGRKLVHFKMIDKG 324 Query: 775 VDPEGNESVWYKGKVIGNTTSGSYSYSIQKSLAFAYVPVELSEVGQQVEVELLGKNYPAT 834 + EG + V+ G++IG TSG+ S + + A+V E ++ G ++EVE+ G+ A Sbjct: 325 IPREGYK-VYANGEMIGEVTSGTLSPLLNVGIGIAFVKEEYAKPGIEIEVEIRGQRKKAV 383 Query: 835 IIQEPL 840 + P Sbjct: 384 TVTPPF 389 >1VRQ-A nrPDB Length = 964 Score = 117 bits (293), Expect = 2e-26, Method: Compositional matrix adjust. Identities = 81/279 (29%), Positives = 136/279 (48%), Gaps = 19/279 (6%) Query: 483 WEQPHWFYKPGQDTQYRPSFRRTNWFRPVGSEYKQVMQRVGVIDLSPFGKFNIKGQDSTQ 542 W++P W+Y ++ +R E K V VG++D S GK I+G+D+ + Sbjct: 595 WKRP-WYYPQDGESMDEAVYR----------ECKAVRDSVGMLDASTLGKIEIRGKDAAE 643 Query: 543 LLDHLCAN--VIPKVGFTNISHMLTPRGRVYAELTVSHQSPGEFLLITGSGSELHDLRWI 600 L+ + N KVG M G ++ + + FL+ T +G L W+ Sbjct: 644 FLNRMYTNGYTKLKVGMGRYGVMCKADGMIFDDGVTLRLAEDRFLMHTTTGGAADVLDWL 703 Query: 601 EE--AAVRGGYDVEIRNITDELGVLGVAGPYARRVLQKLTSE-DLSDDVFKFLQTKSLKI 657 EE DV ++T++L + V GP +R V+ KL S D+S+D FKF+ + + + Sbjct: 704 EEWLQTEWPELDVTCTSVTEQLATVAVVGPRSRDVIAKLASSLDVSNDAFKFMAFQDVTL 763 Query: 658 -SDIPVTAIRISYTGELGWELYHRREDSAALYERIMNAGQEEGIDNFGTYALNALRLEKA 716 S I RIS++GEL +E+ ++E + AGQE I +GT ++ LR EK Sbjct: 764 DSGIEARISRISFSGELAFEIAIPAWHGLQVWEDVYAAGQEFNITPYGTETMHVLRAEKG 823 Query: 717 FRAWGSEMNCDTNPLEAGLDYFIKLNKPADFTGKQALKQ 755 F G + + P +AG+++ + +K DF GK++ + Sbjct: 824 FIIVGQDTDGTVTPQDAGMEWVV--SKLKDFVGKRSFSR 860 >2GAG-A nrPDB Length = 965 Score = 113 bits (283), Expect = 3e-25, Method: Compositional matrix adjust. Identities = 83/293 (28%), Positives = 144/293 (49%), Gaps = 20/293 (6%) Query: 483 WEQPHWFYKPGQDTQYRPSFRRTNWFRPVGSEYKQVMQRVGVIDLSPFGKFNIKGQDSTQ 542 W++P W+Y +T + +R E K V VG++D + GK I+G+D+ + Sbjct: 596 WKRP-WYYPQAGETMDQAVYR----------ESKAVRDSVGMLDATTLGKIEIRGKDAAE 644 Query: 543 LLDHLCAN--VIPKVGFTNISHMLTPRGRVYAELTVSHQSPGEFLLITGSGSELHDLRWI 600 L+ + N KVG M G ++ + + FLL T +G L W+ Sbjct: 645 FLNRIYTNGYTKLKVGMGRYGVMCKADGMIFDDGVTLRLAEDRFLLHTTTGGAADVLDWL 704 Query: 601 EE--AAVRGGYDVEIRNITDELGVLGVAGPYARRVLQKLTSE-DLSDDVFKFLQTKSLKI 657 EE DV ++T++L + V GP +R V+ KL S D+S++ FKF+ K + + Sbjct: 705 EEWLQTEWPDLDVTCTSVTEQLATVAVVGPRSRDVIAKLASTVDVSNEGFKFMAFKDVVL 764 Query: 658 -SDIPVTAIRISYTGELGWELYHRREDSAALYERIMNAGQEEGIDNFGTYALNALRLEKA 716 S I RIS++GEL +E+ ++E + AG+E I +GT ++ LR EK Sbjct: 765 DSGIEARISRISFSGELAFEIAVPAWHGLRVWEDVYAAGEEFNITPYGTETMHVLRAEKG 824 Query: 717 FRAWGSEMNCDTNPLEAGLDYFIKLNKPADFTGKQALKQI-KAKGLKRRLVCL 768 F G + + P +AG+++ + +K DF G ++ + A+ +++LV + Sbjct: 825 FIIVGQDTDGTVTPQDAGMEWVV--SKLKDFIGNRSYSRADNAREDRKQLVSV 875 >3A8J-A nrPDB Length = 364 Score = 94.4 bits (233), Expect = 2e-19, Method: Compositional matrix adjust. Identities = 94/355 (26%), Positives = 160/355 (45%), Gaps = 41/355 (11%) Query: 507 WFRPV--GS---EYKQVMQRVGVIDLSPFGKFNIKGQDSTQLLDHLCANVIPKV---GFT 558 W P+ GS E+ V G+ D+S +++G + + L +L AN + K+ G Sbjct: 24 WMMPLHYGSQIDEHHAVRTDAGMFDVSHMTIVDLRGSRTREFLRYLLANDVAKLTKSGKA 83 Query: 559 NISHMLTPRGRVYAELTVSHQSPGEFLLITGSGSELHDLRWIEEAAVRGGYDVEIRNITD 618 S ML G V +L V + + F L+ S + DL WI + A G ++ +R D Sbjct: 84 LYSGMLNASGGVIDDLIVYYFTEDFFRLVVNSATREKDLSWITQHAEPFGIEITVR---D 140 Query: 619 ELGVLGVAGPYARRVLQKLTSEDLSDDVFKFLQTKSLKISDIPVTAIRISYTGELGWELY 678 +L ++ V GP A+ L ++ V ++ D+ + YTGE G+E+ Sbjct: 141 DLSMIAVQGPNAQAKAATLFNDAQRQAVEGMKPFFGVQAGDLFIATT--GYTGEAGYEIA 198 Query: 679 HRREDSAALYERIMNAGQEEGIDNFGTYALNALRLEKAFRAWGSEMNCDTNPLEAGLDYF 738 E +A + ++ E G+ G A + LRLE +G EM+ +PL A + + Sbjct: 199 LPNEKAADFWRALV----EAGVKPCGLGARDTLRLEAGMNLYGQEMDETISPLAANMGWT 254 Query: 739 IKLNKPA--DFTGKQALKQIKAKGLKRRLVCLTLATDDV----------DPEGNESVWYK 786 I +PA DF G++AL+ + G + +LV L + V D +GN+ Sbjct: 255 IAW-EPADRDFIGREALEVQREHGTE-KLVGLVMTEKGVLRNELPVRFTDAQGNQHE--- 309 Query: 787 GKVIGNTTSGSYSYSIQKSLAFAYVPVELSEVGQQVEVELLGKNYPATIIQEPLV 841 G TSG++S ++ S+A A VP +G+ V++ + P + + V Sbjct: 310 ----GIITSGTFSPTLGYSIALARVP---EGIGETAIVQIRNREMPVKVTKPVFV 357 >1WSR-A nrPDB Length = 375 Score = 88.6 bits (218), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 98/377 (25%), Positives = 162/377 (42%), Gaps = 44/377 (11%) Query: 481 AGWEQPHWFYKPGQDTQYRPSFRRTNWFRPVGSEYKQVMQRVGVIDLSPFGKFNIKGQDS 540 AGW P QYR S ++ Q + D+S + I G D Sbjct: 25 AGWSLP---------VQYRDSHTDSHL---------HTRQHCSLFDVSHMLQTKILGSDR 66 Query: 541 TQLLDHLC----ANVIPKVGFTNISHMLTPRGRVYAELTVSHQSPGEFLLITGSGSELHD 596 +L++ L A + P G +S G + +L V++ S G +++ +G D Sbjct: 67 VKLMESLVVGDIAELRPNQG--TLSLFTNEAGGILDDLIVTNTSEGHLYVVSNAGCWEKD 124 Query: 597 LRWIEEAA---VRGGYDVEIRNITDELGVLGVAGPYARRVLQKLTSEDLSDDVFKFLQTK 653 L +++ G DV + + + L L + GP A +VLQ ++DL F+ + Sbjct: 125 LALMQDKVRELQNQGRDVGLEVLDNAL--LALQGPTAAQVLQAGVADDLRK--LPFMTSA 180 Query: 654 SLKISDIP-VTAIRISYTGELGWELYHRREDSAALYERIMNAGQEEGIDNFGTYALNALR 712 +++ + R YTGE G E+ + L I+ + + G A ++LR Sbjct: 181 VMEVFGVSGCRVTRCGYTGEDGVEISVPVAGAVHLATAILKNPE---VKLAGLAARDSLR 237 Query: 713 LEKAFRAWGSEMNCDTNPLEAGLDYFIKLNKPA--DFTG-KQALKQIKAKGLKRR--LVC 767 LE +G++++ T P+E L + + + A DF G K + Q+K + +RR L+C Sbjct: 238 LEAGLCLYGNDIDEHTTPVEGSLSWTLGKRRRAAMDFPGAKVIVPQLKGRVQRRRVGLMC 297 Query: 768 LTLATDDVDPEGNESVWYKGKVIGNTTSGSYSYSIQKSLAFAYVPVELSEVGQQVEVELL 827 P N +G IG TSG S S++K++A YVP E S G + VE+ Sbjct: 298 EGAPMRAHSPILN----MEGTKIGTVTSGCPSPSLKKNVAMGYVPCEYSRPGTMLLVEVR 353 Query: 828 GKNYPATIIQEPLVLTE 844 K A + + P V T Sbjct: 354 RKQQMAVVSKMPFVPTN 370 >3GIR-A nrPDB Length = 393 Score = 87.8 bits (216), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 89/338 (26%), Positives = 148/338 (43%), Gaps = 19/338 (5%) Query: 510 PVG--SEYKQVMQRVGVIDLSPFGKFNIKGQDSTQLLDHL--CANVIPKVGFTNISHMLT 565 P+G E+ G+ D+S ++G + + L + + K+G + S++L Sbjct: 62 PLGVLKEHLHTRAHAGLFDISHMKLIAVEGPKAVEFLSYALPVDAALLKIGQSRYSYLLN 121 Query: 566 PRGRVYAELTVSHQSPGEFLLITGSGSELHDLRWIEEAAVRGGYDVEIRNITDELGVLGV 625 R + +L ++ + F+L+ +G+ D +E+ A + E + I E +L + Sbjct: 122 ERAGILDDLILTRLAECRFMLVANAGNAQADFAELEKRA----FGFECQVIALERVLLAL 177 Query: 626 AGPYARRVLQKLTSEDLSDDVFKFLQTKSLKISDIPVTAIRISYTGELGWELYHRREDSA 685 GP A VL L + F+Q + D +T R YTGE G+E+ + Sbjct: 178 QGPQAAAVL---ADAGLPGNELLFMQGFEPQ-QDWFIT--RSGYTGEDGFEIALPIGCAR 231 Query: 686 ALYERIMNAGQEEGIDNFGTYALNALRLEKAFRAWGSEMNCDTNPLEAGLDYFIKLN--K 743 AL E+++ + E + G A ++LRLE G+++ DT P++A L + + N + Sbjct: 232 ALAEKLLGDSRVEWV---GLAARDSLRLEAGLCLHGNDITPDTTPIDAALTWAVPKNVRE 288 Query: 744 PADFTGKQALKQIKAKGLKRRLVCLTLATDDVDPEGNESVWYKGKVIGNTTSGSYSYSIQ 803 A F G +A + KG R V L T G +G IG TSG + S Sbjct: 289 KAQFYGAKAFLESLQKGPSRCRVGLKPQTRQPIRAGAVLFDNEGNRIGVVTSGGFGPSFD 348 Query: 804 KSLAFAYVPVELSEVGQQVEVELLGKNYPATIIQEPLV 841 +A YVPV G +V EL GK ++ P V Sbjct: 349 GPVAMGYVPVAWKVEGTEVFTELRGKKIALSVHSLPFV 386 >2GAG-B nrPDB Length = 405 Score = 77.0 bits (188), Expect = 3e-14, Method: Compositional matrix adjust. Identities = 91/395 (23%), Positives = 161/395 (40%), Gaps = 38/395 (9%) Query: 37 PEWKDRAETVIIGGGCVGVSLAYHLAKA-GMRDVVLLEKSELTAGSTWHAAGLTTYFHPG 95 PE K + +I+GGG G++ AY LAK G+ +V +LEK L G+ + + Sbjct: 16 PEPKKSYDAIIVGGGGHGLATAYFLAKNHGITNVAVLEKGWLAGGNMARNTTIIRSNYLW 75 Query: 96 INLKKIHYDSIKLYERLEEETGQVVGFHQPGSIRLATTPERVDEFKYQMTRTNWHATEQY 155 I+ S+KL+E+L E+ F Q G + LA T V E ++ + + Sbjct: 76 DESAGIYEKSLKLWEQLPEDLEYDFLFSQRGVLNLAHTLGDVRESVRRVEANKLNGVDAE 135 Query: 156 IIEPEKIHELFPLLNMDK-----ILAGLYNPGDGHIDPYSLTMALATGARKYGVLLKYPA 210 ++P ++ E P++N ++ + P G + A A A + GV + Sbjct: 136 WLDPSQVKEACPIINTSDDIRYPVMGATWQPRAGIAKHDHVAWAFARKANEMGVDIIQNC 195 Query: 211 PVTSLKPRPDGTWDVETPQGSVRANRIVNAAGFWAREVGKMIGLDHPLIPVQHQYVVTST 270 VT + V+T +G++ A ++ A + + +M G + P+ Q +V+ Sbjct: 196 EVTGFIKDGEKVTGVKTTRGTIHAGKVALAGAGHSSVLAEMAGFELPIQSHPLQALVSEL 255 Query: 271 IPEVKALKRELPVLRDLEGSYYLRQERDGLLFGPYESQEKMKLQASWVAHGVPP--GFGK 328 V V+ Y+ Q G L + G+ G+G+ Sbjct: 256 FEPVHPT-----VVMSNHIHVYVSQAHKGELV---------------MGAGIDSYNGYGQ 295 Query: 329 ELFESDLDRITEHVEAAMEMVPVLKKADIINIVNGPITYSPDILPMVGPHQGVRNYWVAI 388 I E + AA+E+ P+ +A ++ G + + D P++ ++N +V Sbjct: 296 ---RGAFHVIQEQMAAAVELFPIFARAHVLRTWGGIVDTTMDASPIISK-TPIQNLYVNC 351 Query: 389 GFGYGIIHAG-GVGKYLSDWILHGEP-----PFDL 417 G+G G G G L+ I + EP PF L Sbjct: 352 GWGTGGFKGTPGAGFTLAHTIANDEPHELNKPFSL 386 >3TFJ-A nrPDB Length = 369 Score = 70.9 bits (172), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 69/345 (20%), Positives = 152/345 (44%), Gaps = 27/345 (7%) Query: 508 FRPVGSEYKQVMQRVGVIDLSPFGKFNIKGQDSTQLLDHLCANVIPK--VGFTNISHMLT 565 F + YK + + V + D++ + I G+DS +L+ + + K +G ++ Sbjct: 41 FGSIEDSYKHLKEHVQIWDVAAERQVEISGKDSAELVQLMTCRDLSKSKIGRCYYCPIID 100 Query: 566 PRGRVYAELTVSHQSPGEFLLITGSGSELHDLRWIEEAAVRGGYDVEIRNITDELGVLGV 625 G + + V ++ + + + + G+ +++ + + ++ + Sbjct: 101 ENGNLVNDPVVLKLDENKWWISIADSDVIFFAK-----GLASGHKFDVKIVEPVVDIMAI 155 Query: 626 AGPYARRVLQKLTSEDLSD------DVFKFLQTKSLKISDIPVTAIRISYTGELGWELYH 679 GP + +++K+ + +++ D F F TK L R ++ + G+E+Y Sbjct: 156 QGPKSFALMEKVFGKKITELKFFGFDYFDFEGTKHL--------IARSGWSKQGGYEVYV 207 Query: 680 RREDSA-ALYERIMNAGQEEGIDNFGTYALNAL-RLEKAFRAWGSEMNCDTNPLEAGLDY 737 S LY+ + G+E N G N + R+E A ++G++ + + NP E G D Sbjct: 208 ENTQSGQKLYDHLFEVGKEF---NVGPGCPNLIERIESALLSYGNDFDNNDNPFECGFDQ 264 Query: 738 FIKLNKPADFTGKQALKQIKAKGLKRRLVCLTLATDDVDPEGNESVW-YKGKVIGNTTSG 796 ++ L+ +F GK+ LK+IK KG +++L + + ++ G+++++ VIG S Sbjct: 265 YVSLDSDINFLGKEKLKEIKLKGPQKKLRGVKIDIKEISLTGSKNIYDENNNVIGELRSA 324 Query: 797 SYSYSIQKSLAFAYVPVELSEVGQQVEVELLGKNYPATIIQEPLV 841 YS QK + A + E Q ++++ + P + Sbjct: 325 CYSPHFQKVIGIAMIKKSHWEASQGFKIQINDNTINGNVCDLPFI 369 >1NG3-A nrPDB Length = 390 Score = 67.8 bits (164), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 89/367 (24%), Positives = 152/367 (41%), Gaps = 50/367 (13%) Query: 59 YHLAKAGMRDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKIHYD----SIKLYERLEE 114 Y+LAK ++ L E + +T AAG+ H + +D S +LY+ L E Sbjct: 42 YYLAKEN-KNTALFESGTMGGRTTSAAAGMLGA-HAECEERDAFFDFAMHSQRLYKGLGE 99 Query: 115 ETGQVVGF----HQPGSIRLATTPERVDEFKY--QMTRTNWHATEQYIIEPEKIHELFPL 168 E + G H G +LA + E V + + + +W++ E+ ++E E P Sbjct: 100 ELYALSGVDIRQHNGGMFKLAFSEEDVLQLRQMDDLDSVSWYSKEE-VLEKE------PY 152 Query: 169 LNMDKILAGLYNPGDGHIDPYSLTMALATGARKYGVLLKYPAPVTSLKPRPDGTWDVETP 228 + D I + D H++PY + A A+ G + PV ++ + + ++TP Sbjct: 153 ASGD-IFGASFIQDDVHVEPYFVCKAYVKAAKMLGAEIFEHTPVLHVERDGEALF-IKTP 210 Query: 229 QGSVRANRIVNAAGFWAREVGKMIGLDHPLIPVQHQY--VVTSTIPEVKALKRELPVLRD 286 G V AN +V A+G W+ K +GL++ +PV+ + V IP K L + Sbjct: 211 SGDVWANHVVVASGVWSGMFFKQLGLNNAFLPVKGECLSVWNDDIPLTKTLYHD------ 264 Query: 287 LEGSYYLRQERDGLLFGPYESQEKMKLQASWVAHGVPPGFGKELFESDLDRITEHVEAAM 346 Y+ + G L V + PG E DL + ++ A Sbjct: 265 ---HCYIVPRKSGRLV---------------VGATMKPGDWSE--TPDLGGLESVMKKAK 304 Query: 347 EMVPVLKKADIINIVNGPITYSPDILPMVGPH-QGVRNYWVAIGFGYGIIHAGGVGKYLS 405 M+P ++ + G + D P +G H + R + A F GI+ A G +S Sbjct: 305 TMLPPIQNMKVDRFWAGLRPGTKDGKPYIGRHPEDSRILFAAGHFRNGILLAPATGALIS 364 Query: 406 DWILHGE 412 D I++ E Sbjct: 365 DLIMNKE 371 >3SM8-A nrPDB Length = 381 Score = 66.2 bits (160), Expect = 5e-11, Method: Compositional matrix adjust. Identities = 96/396 (24%), Positives = 160/396 (40%), Gaps = 58/396 (14%) Query: 43 AETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKIH 102 A+ ++IG G G S Y L+ G R VVL +++ ST +A T + ++ + Sbjct: 10 ADYLVIGAGIAGASTGYWLSAHG-RVVVLEREAQPGYHSTGRSAAHYTVAYGTPQVRALT 68 Query: 103 YDSIKLYERLEEETGQVVGFHQPGSIRLATTPERV-------DEFKYQMTRTNWHATEQY 155 S ++ GF + L+ PE V +E + Q + Sbjct: 69 AASRAFFDN------PPAGFCE--HPLLSPRPEMVVDFSDDPEELRRQYESGKALVPQMR 120 Query: 156 IIEPEKIHELFPLLNMDKILAGLYNPGDGHIDPYSLTMALATGARKYG--VLLKYPAPVT 213 +++ E+ + P+L DK+ Y+P ID +L G R+ VL + A Sbjct: 121 LLDAEQACSIVPVLRRDKVFGATYDPTGADIDTDALHQGYLRGIRRNQGQVLCNHEALEI 180 Query: 214 SLKPRPDGTWDVETPQGSVRANRIVNAAGFWAREVGKMIGLDHP--LIPVQHQYVVTSTI 271 R DG W+V GS RA +VNAAG W + + G+ P L P + + + Sbjct: 181 R---RVDGAWEVRCDAGSYRAAVLVNAAGAWCDAIAGLAGV-RPLGLQPKRRSAFIFAPP 236 Query: 272 PEVKALKRELPVLRDLEGSYYLRQERDGLLFGPYESQEKMKLQASWVAHGVPPGFGKELF 331 P + + P+L L+ S+YL+ + G+L G + + ++ AH V P Sbjct: 237 PGIDC--HDWPMLVSLDESFYLKPDA-GMLLGSPANADPVE------AHDVQP------- 280 Query: 332 ESDLDRITEHVEAAMEMVPVLKKADIINIVNGPITYSPDILPMVGPHQGVRNY------- 384 E ++ A M ++++A + I T++ + V V Y Sbjct: 281 --------EQLDIATGMY-LIEEATTLTIRRPEHTWA-GLRSFVADGDLVAGYAANAEGF 330 Query: 385 -WVAIGFGYGIIHAGGVGKYLSDWILHGEPPFDLIE 419 WVA GYGI + +G+ + I H P L E Sbjct: 331 FWVAAQGGYGIQTSAAMGEASAALIRHQPLPAHLRE 366 >4YSH-A nrPDB Length = 376 Score = 63.9 bits (154), Expect = 3e-10, Method: Compositional matrix adjust. Identities = 83/326 (25%), Positives = 139/326 (42%), Gaps = 40/326 (12%) Query: 108 LYERLEEETGQVVGFHQPGSIRLATTPERVDEFKYQMTRTNWHATE---QYIIEPEKIHE 164 L E L E TG +G + G I+LATT E D+ T W Q++ + E + E Sbjct: 76 LAEELRERTGIDIGLVEKGLIKLATTEEEADDLYRHYT--FWRGIGEPVQWLTKGEAL-E 132 Query: 165 LFPLLNMDKILAGLYNPGDGHIDPYSLTMALATGARKYGVLLKYPAPVTSLKPRPDGTWD 224 + P L + + +Y PGDG + L ALA A G L V ++ G Sbjct: 133 MEPRLA-EALAGAMYIPGDGQVSAPDLAAALAYAAASAGACLYEYTEVFDIRSDSSGHV- 190 Query: 225 VETPQGSVRANRIVNAAGFWAREVGKMIGLDHPLIPVQHQYVVTSTIPEVKALKRELPVL 284 ++T G+ A +V A+G WA +G +GL + PV+ + V+ ++ +P+L Sbjct: 191 LDTTGGTFAAEAVVIASGAWAARLGARVGLSLSVYPVKGECVM---------VRAPVPLL 241 Query: 285 RDL----EGSYYLRQERDGLLFGPYESQEKMKLQASWVAHGVPPGFGKELFESDLDRITE 340 + G Y + + + LL G A P F + + + + Sbjct: 242 QTTVFAKNGCYIVPKSGNRLLIG---------------ATSTPGTFDRRVSAGGVMNL-- 284 Query: 341 HVEAAMEMVPVLKKADIINIVNGPITYSPDILPMVGPHQGVRNYWVAIG-FGYGIIHAGG 399 + A +VP +++A+ + +G + D LP +G H R +VA G + GI+ + Sbjct: 285 -LHRAAHLVPDIEQAEWVASWSGIRPQTEDGLPYLGEHPERRGLFVAAGHYRNGILLSPL 343 Query: 400 VGKYLSDWILHGEPPFDLIELDPNRY 425 G ++D + E FDL R+ Sbjct: 344 TGLLVADLVERKETAFDLAPFSLTRH 369 >3AD9-B nrPDB Length = 404 Score = 54.7 bits (130), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 85/384 (22%), Positives = 153/384 (39%), Gaps = 52/384 (13%) Query: 55 VSLAYHLAKA-GMRDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKIHYDSIKLYERLE 113 ++ AY+LAK G+ +V +LEK L G+ A TT I + +S +YE+ Sbjct: 33 LATAYYLAKNHGITNVAVLEKGWLAGGNM---ARNTTI----IRSNYLWDESAGIYEKSL 85 Query: 114 EETGQVVG-------FHQPGSIRLATTPERVDEFKYQMTRTNWHATEQYIIEPEKIHELF 166 + ++ F Q G + LA T V E ++ ++ + + PE++ E+ Sbjct: 86 KLWEELPEELEYDFLFSQRGVLNLAHTLGDVRESIRRVEANKFNGVDAEWLTPEQVKEVC 145 Query: 167 PLLNMDK-----ILAGLYNPGDGHIDPYSLTMALATGARKYGVLLKYPAPVTSLKPRPDG 221 P++N ++ Y P G + A A A + GV + VT + Sbjct: 146 PIINTGDNIRYPVMGATYQPRAGIAKHDHVAWAFARKANEMGVDIIQNCEVTGFLKDGEK 205 Query: 222 TWDVETPQGSVRANRIVNAAGFWAREVGKMIGLDHPLIPVQHQYVVTSTIPEVKALKREL 281 V+T +G++ A ++ A + + ++ G + P+ Q +V+ V Sbjct: 206 VTGVKTTRGTILAGKVALAGAGHSSVLAELAGFELPIQSHPLQALVSELFEPVHPT---- 261 Query: 282 PVLRDLEGSYYLRQERDGLLFGPYESQEKMKLQASWVAHGVPP--GFGKELFESDLDRIT 339 V+ Y+ Q G L + G+ G+G+ I Sbjct: 262 -VVMSNHIHVYVSQAHKGELV---------------MGAGIDSYNGYGQ---RGAFHVIE 302 Query: 340 EHVEAAMEMVPVLKKADIINIVNGPITYSPDILPMVGPHQGVRNYWVAIGFGYGIIHAG- 398 E + AA+E+ P+ +A ++ G + + D P++ ++N +V G+G G Sbjct: 303 EQMAAAVELFPIFARAHVLRTWGGIVDTTMDASPIISK-TPIQNLYVNCGWGTGGFKGTP 361 Query: 399 GVGKYLSDWILHGEP-----PFDL 417 G G L+ I H EP PF L Sbjct: 362 GAGYTLAHTIAHDEPHKLNAPFAL 385 >3BHF-A nrPDB Length = 390 Score = 45.1 bits (105), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 84/393 (21%), Positives = 159/393 (40%), Gaps = 32/393 (8%) Query: 44 ETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAGLTTYFHP---GINLKK 100 + +++G G +G++ Y LAK G++ +L++ + + H H G Sbjct: 6 DVIVVGAGSMGMAAGYQLAKQGVK-TLLVDAFDPPHTNGSHHGDTKIIRHAYGEGREYVP 64 Query: 101 IHYDSIKLYERLEEETGQVVGFHQPGSIRLATTPERVDEFKYQ-MTRTNWHATEQYIIEP 159 + S +L+ LE+ET + F + G + P+ F + M H+ ++E Sbjct: 65 LALRSQELWYELEKETHHKI-FTKTGVLVFG--PKGESAFVAETMEAAKEHSLTVDLLEG 121 Query: 160 EKIHELFPLLNMDKILAGLYNPGDGHIDPYSLTMALATGARKYGVLLKYPAPVTSLKPRP 219 ++I++ +P + + + ++ P G + + A A G + V P Sbjct: 122 DEINKRWPGITVPENYNAIFEPNSGVLFSENCIRAYRELAEARGAKVLTHTRVEDFDISP 181 Query: 220 DGTWDVETPQGSVRANRIVNAAGFWAREVGKMIGLDHPLIPVQHQYVVTSTIPEVKALKR 279 D + +ET GS A++++ + G W ++ + LD PL P + Q V E K Sbjct: 182 D-SVKIETANGSYTADKLIVSMGAWNSKLLSKLNLDIPLQPYR-QVVGFFESDESK---- 235 Query: 280 ELPVLRDLEGSYYLRQERDGLLFG-PYESQEKMKLQASWVAHGVPPG-----FGKELFES 333 D++ ++ + +G+ +G P +KL + P FG ++ Sbjct: 236 ---YSNDIDFPGFMVEVPNGIYYGFPSFGGCGLKLGYHTFGQKIDPDTINREFG--VYPE 290 Query: 334 DLDRITEHVEAAMEMVP-VLKKADIINIVNGPITYSPDILPMVGPHQGVRNYWVAIGF-G 391 D + +E M LK+ + T + D ++ H N +A GF G Sbjct: 291 DESNLRAFLEEYMPGANGELKRGAVCM-----YTKTLDEHFIIDLHPEHSNVVIAAGFSG 345 Query: 392 YGIIHAGGVGKYLSDWILHGEPPFDLIELDPNR 424 +G + GVG+ LS L G+ D+ NR Sbjct: 346 HGFKFSSGVGEVLSQLALTGKTEHDISIFSINR 378 >1ZOV-A nrPDB Length = 386 Score = 43.1 bits (100), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 45/220 (20%), Positives = 95/220 (43%), Gaps = 7/220 (3%) Query: 44 ETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAG--LTTYFHPGINLKKI 101 + +++G G +G++ Y+LAK G++ +++ + H + + G Sbjct: 5 DVIVVGAGSMGMAAGYYLAKQGVKTLLVDSFDPPHTNGSHHGDTRIIRHAYGEGREYVPF 64 Query: 102 HYDSIKLYERLEEETGQVVGFHQPGSIRLATTPERVDEFKYQ-MTRTNWHATEQYIIEPE 160 + +L+ LE+ET + F Q G L P+ F + M N H+ E + E + Sbjct: 65 ALRAQELWYELEKETHHKI-FTQTGV--LVYGPKGGSAFVSETMEAANIHSLEHELFEGK 121 Query: 161 KIHELFPLLNMDKILAGLYNPGDGHIDPYSLTMALATGARKYGVLLKYPAPVTSLKPRPD 220 ++ + + + + ++ P G + + A A +G + PV + D Sbjct: 122 QLTDRWAGVEVPDNYEAIFEPNSGVLFSENCIQAYRELAEAHGATVLTYTPVEDFEVTED 181 Query: 221 GTWDVETPQGSVRANRIVNAAGFWAREVGKMIGLDHPLIP 260 ++T +GS AN++V + G W ++ + ++ PL P Sbjct: 182 -LVTIKTAKGSYTANKLVVSMGAWNSKLLSKLDVEIPLQP 220 >2UZZ-A nrPDB Length = 372 Score = 37.7 bits (86), Expect = 0.022, Method: Compositional matrix adjust. Identities = 90/424 (21%), Positives = 152/424 (35%), Gaps = 94/424 (22%) Query: 42 RAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTA-------GST---WHAAGLTTY 91 + + +IIG G VG + Y+ +AG+ VL+ + + G T HA G Sbjct: 2 KYDLIIIGSGSVGAAAGYYATRAGLN--VLMTDAHMPPHQHGSHHGDTRLIRHAYGEGEK 59 Query: 92 FHPGINLKKIHYDSIKLYERLEEETGQVVGFHQPGSIRLATTPERVDEFKYQMTRTNWHA 151 + P + ++ L++ L F + G I L H+ Sbjct: 60 YVPLVLRAQM------LWDELSRHNEDDPIFVRSGVINLGPADS-------TFLANVAHS 106 Query: 152 TEQYIIEPEK-----IHELFPLLNMDKILAGLYNPGDGHIDPYSLTMALATGARKYGVLL 206 EQ+ + EK I +P + + GL+ G + A++ G Sbjct: 107 AEQWQLNVEKLDAQGIMARWPEIRVPDNYIGLFETDSGFLRSELAIKTWIQLAKEAGCAQ 166 Query: 207 KYPAPVTSLKPRPDGTWDVETPQGSVRANRIVNAAGFWAREVGKMIGLDHPLIPVQ---- 262 + PVT+++ DG +ET G +A + + AG W +++ P +PVQ Sbjct: 167 LFNCPVTAIRHDDDGV-TIETADGEYQAKKAIVCAGTWVKDL-------LPELPVQPVRK 218 Query: 263 --------HQYVVTSTIPEVKALKRELPVLRDLEGSYYLRQERDGLLFGPYESQEKMKLQ 314 +Y V + P A ELP + + Y E D L G + Sbjct: 219 VFAWYQADGRYSVKNKFP---AFTGELP---NGDQYYGFPAENDALKIGKHN-------- 264 Query: 315 ASWVAHGVPPGFGKELFESDLDRI--TEHVEAAMEMVPVLKKADIINIVNG--------P 364 G ++ S +R+ E V E P L+ N++ G Sbjct: 265 ------------GGQVIHSADERVPFAEVVSDGSEAFPFLR-----NVLPGIGCCLYGAA 307 Query: 365 ITY--SPDILPMVGPHQGVRNYWVAIGF-GYGIIHAGGVGKYLSDWILHGEPPFDLIELD 421 TY SPD ++ G N + G G+G A +G+ +D+ + FDL Sbjct: 308 CTYDNSPDEDFIIDTLPGHDNTLLITGLSGHGFKFASVLGEIAADFAQDKKSDFDLTPFR 367 Query: 422 PNRY 425 +R+ Sbjct: 368 LSRF 371 >2GAH-C nrPDB Length = 210 Score = 37.0 bits (84), Expect = 0.041, Method: Composition-based stats. Identities = 29/101 (28%), Positives = 45/101 (44%), Gaps = 7/101 (6%) Query: 580 SPGEFLLITGSGSELHDLRWIEEAAVRGGYDVEIRNITDELGVLGVAGPYARRVLQKLTS 639 +P EFL + +EL + +A G ++ +++ VL + GP A VL+K Sbjct: 85 APDEFLATSAENTELGGVL----SAALGDAPGQVVDLSANRSVLELTGPDAPLVLRKSCP 140 Query: 640 EDLSDDVFKFLQTKSLKISDIPVTAIRISYTGELGWELYHR 680 DL F Q +++IPV R TGE W + R Sbjct: 141 ADLHPRAFAVNQAIVTSVANIPVLLWR---TGEQAWRIMPR 178 >1KNR-A nrPDB Length = 540 Score = 35.0 bits (79), Expect = 0.16, Method: Compositional matrix adjust. Identities = 19/45 (42%), Positives = 27/45 (60%), Gaps = 2/45 (4%) Query: 43 AETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAG 87 + +IIG G G+SLA LA V++L K +T GST++A G Sbjct: 9 CDVLIIGSGAAGLSLALRLAD--QHQVIVLSKGPVTEGSTFYAQG 51 >5KXJ-A nrPDB Length = 557 Score = 33.9 bits (76), Expect = 0.35, Method: Compositional matrix adjust. Identities = 18/45 (40%), Positives = 28/45 (62%), Gaps = 2/45 (4%) Query: 43 AETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAG 87 + +IIG G G+SLA LA+ V++L K ++ GST++A G Sbjct: 9 CDVLIIGSGAAGLSLALRLAEK--HKVIVLSKGPVSEGSTFYAQG 51 >4IV9-A nrPDB Length = 557 Score = 33.5 bits (75), Expect = 0.42, Method: Compositional matrix adjust. Identities = 15/39 (38%), Positives = 21/39 (53%) Query: 45 TVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTW 83 I+G G G+ A L +AG++DVVL E + G W Sbjct: 41 VAIVGAGISGLVAATELLRAGVKDVVLYESRDRIGGRVW 79 >4C5O-A nrPDB Length = 357 Score = 33.5 bits (75), Expect = 0.44, Method: Compositional matrix adjust. Identities = 17/46 (36%), Positives = 26/46 (56%), Gaps = 2/46 (4%) Query: 41 DRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAA 86 D + V+IGGG G+S Y L ++G+ V+L +E + G W A Sbjct: 2 DSVDVVVIGGGQSGLSAGYFLRRSGLSYVIL--DAEASPGGAWQHA 45 >5MOG-A nrPDB Length = 497 Score = 33.5 bits (75), Expect = 0.46, Method: Compositional matrix adjust. Identities = 27/105 (25%), Positives = 49/105 (46%), Gaps = 13/105 (12%) Query: 44 ETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGST---------WHAAGLTTYFHP 94 + VI G G G+S A +LA AG + +LLE ++ G W+ GL +F Sbjct: 19 QVVIAGAGLAGLSTAKYLADAGHKP-ILLEARDVLGGKIAAWKDEDGDWYETGLHIFFGA 77 Query: 95 GINLKKIHYDSIKLYERLE-EETGQVVGF-HQPGSIRLATTPERV 137 N++ + + + + +RL+ +E + ++PG PE + Sbjct: 78 YPNIQNL-FGELGINDRLQWKEHSMIFAMPNKPGEFSRFDFPETL 121 >6QZO-A nrPDB Length = 383 Score = 32.3 bits (72), Expect = 0.80, Method: Compositional matrix adjust. Identities = 16/37 (43%), Positives = 21/37 (56%), Gaps = 1/37 (2%) Query: 386 VAIGFGYGIIHAGGVGKYLSDWILHGEPPFDLIELDP 422 V +GFG G++ A G+ W LH PPF + LDP Sbjct: 101 VTVGFGPGLLTAAGLRHRAPAW-LHPLPPFGIDRLDP 136 >3L1R-A nrPDB Length = 478 Score = 32.3 bits (72), Expect = 0.85, Method: Compositional matrix adjust. Identities = 12/36 (33%), Positives = 24/36 (66%) Query: 45 TVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAG 80 +++G G G+S A L++AG+ D+++LE ++ G Sbjct: 7 VIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGG 42 >3S2F-A nrPDB Length = 340 Score = 32.3 bits (72), Expect = 0.97, Method: Compositional matrix adjust. Identities = 16/42 (38%), Positives = 24/42 (57%) Query: 554 KVGFTNISHMLTPRGRVYAELTVSHQSPGEFLLITGSGSELH 595 KVGF I+ +L VY L V+ PG++++I+G G H Sbjct: 139 KVGFVEIAPILCAGVTVYKGLKVTDTRPGQWVVISGIGGLGH 180 >4UIR-A nrPDB Length = 646 Score = 32.0 bits (71), Expect = 1.1, Method: Compositional matrix adjust. Identities = 18/67 (26%), Positives = 32/67 (47%), Gaps = 3/67 (4%) Query: 18 QGRPSSAGLREGQESPPSPPEWKDRAETVIIGGGCVGVSLAYHLAKAG---MRDVVLLEK 74 + P S + Q + P + D ++ IIG G G+S AY+ + G +++ LE+ Sbjct: 38 KSMPFSDQIGNYQRNKGIPVQSYDNSKIYIIGSGIAGMSAAYYFIRDGHVPAKNITFLEQ 97 Query: 75 SELTAGS 81 + GS Sbjct: 98 LHIDGGS 104 >2JB2-A nrPDB Length = 489 Score = 31.6 bits (70), Expect = 1.7, Method: Compositional matrix adjust. Identities = 17/42 (40%), Positives = 23/42 (54%), Gaps = 1/42 (2%) Query: 46 VIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAG 87 V++GGG G+ A+ L KAG + V +LE G W A G Sbjct: 15 VVLGGGPAGLCSAFELQKAGYK-VTVLEARTRPGGRVWTARG 55 >3KVE-A nrPDB Length = 486 Score = 31.2 bits (69), Expect = 1.9, Method: Compositional matrix adjust. Identities = 17/35 (48%), Positives = 22/35 (62%), Gaps = 1/35 (2%) Query: 46 VIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAG 80 V++G G G+S AY LA AG + V +LE SE G Sbjct: 37 VVVGAGMSGLSAAYVLAGAGHK-VTVLEASERAGG 70 >1F8S-A nrPDB Length = 498 Score = 31.2 bits (69), Expect = 2.1, Method: Compositional matrix adjust. Identities = 18/36 (50%), Positives = 22/36 (61%), Gaps = 1/36 (2%) Query: 45 TVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAG 80 VI+G G G+S AY LA AG + V +LE SE G Sbjct: 36 VVIVGAGMAGLSAAYVLAGAGHQ-VTVLEASERPGG 70 >3RHA-A nrPDB Length = 482 Score = 30.8 bits (68), Expect = 2.4, Method: Compositional matrix adjust. Identities = 16/40 (40%), Positives = 23/40 (57%), Gaps = 1/40 (2%) Query: 44 ETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTW 83 + VI+G G G++ A L KAG+ V +LE + G TW Sbjct: 9 DVVIVGAGPSGLTAARELKKAGLS-VAVLEARDRVGGRTW 47 >4Y4M-A nrPDB Length = 290 Score = 30.8 bits (68), Expect = 2.7, Method: Compositional matrix adjust. Identities = 20/67 (29%), Positives = 35/67 (52%), Gaps = 8/67 (11%) Query: 7 LRLRGLALRSSQGRPSSAGLREGQESPPSPPEWKD--RAETVIIGGGCVGVSLAYHLAKA 64 + ++ + L + + + + A L+ S W D A+ VI+G G G++ A +LAK Sbjct: 28 MNIKDIKLNADETKTTKAILK------ASFDMWLDIVEADVVIVGAGPSGLTCARYLAKE 81 Query: 65 GMRDVVL 71 G + VVL Sbjct: 82 GFKVVVL 88 >1VRQ-C nrPDB Length = 206 Score = 30.8 bits (68), Expect = 2.9, Method: Composition-based stats. Identities = 28/100 (28%), Positives = 41/100 (41%), Gaps = 7/100 (7%) Query: 581 PGEFLLITGSGSELHDLRWIEEAAVRGGYDVEIRNITDELGVLGVAGPYARRVLQKLTSE 640 P EFLL L D G ++ +++ VL + GP A VL+K Sbjct: 84 PDEFLLAAEENPALLDTL----QGALGQEPGQVLDLSANRSVLQLEGPAAALVLRKSCPA 139 Query: 641 DLSDDVFKFLQTKSLKISDIPVTAIRISYTGELGWELYHR 680 DL F + + +++IPV R TGE W + R Sbjct: 140 DLHPREFGVNRAITTSLANIPVLLWR---TGEQSWRILPR 176 >4IVM-B nrPDB Length = 483 Score = 30.4 bits (67), Expect = 3.1, Method: Compositional matrix adjust. Identities = 16/37 (43%), Positives = 24/37 (64%), Gaps = 1/37 (2%) Query: 45 TVIIGGGCVGVSLAYHLAKAGM-RDVVLLEKSELTAG 80 V++GGG G++ +YHL++A VVL+E SE G Sbjct: 11 VVVLGGGISGLAASYHLSRAPCPPKVVLVESSERLGG 47 >4K28-A nrPDB Length = 269 Score = 30.4 bits (67), Expect = 3.2, Method: Composition-based stats. Identities = 15/42 (35%), Positives = 24/42 (57%) Query: 46 VIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAG 87 ++IG G VG ++AY LA+AG+ + L + S G+ G Sbjct: 129 LVIGCGGVGSAIAYALAEAGIASITLCDPSTARMGAVCELLG 170 >3ATQ-A nrPDB Length = 453 Score = 30.4 bits (67), Expect = 3.7, Method: Compositional matrix adjust. Identities = 24/82 (29%), Positives = 41/82 (50%), Gaps = 11/82 (13%) Query: 42 RAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKI 101 + + +IIGGG G S AY L++ G++ +LL S+ W+ G G + K Sbjct: 6 KYDVLIIGGGFAGSSAAYQLSRRGLK--ILLVDSK-----PWNRIGDKP---CGDAVSKA 55 Query: 102 HYDSIKL-YERLEEETGQVVGF 122 H+D + + Y + EE ++ G Sbjct: 56 HFDKLGMPYPKGEELENKINGI 77 >2IVE-A nrPDB Length = 478 Score = 30.0 bits (66), Expect = 4.4, Method: Compositional matrix adjust. Identities = 15/39 (38%), Positives = 22/39 (56%), Gaps = 1/39 (2%) Query: 44 ETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGST 82 ++GGG G+++A+HL G D VLLE S G+ Sbjct: 18 NVAVVGGGISGLAVAHHLRSRGT-DAVLLESSARLGGAV 55 >3RO8-A nrPDB Length = 341 Score = 29.6 bits (65), Expect = 5.1, Method: Compositional matrix adjust. Identities = 15/48 (31%), Positives = 26/48 (54%), Gaps = 4/48 (8%) Query: 491 KPGQDTQYRPSFRRTNWFRPVGSEY--KQVMQRVGVIDLSPFGKFNIK 536 P Y+ S R+T W++ +GS+Y + + V+D +P +NIK Sbjct: 143 NPSNPADYKASLRQTPWYQAIGSDYVEQAFLAAREVLDENP--SWNIK 188 >1RP0-A nrPDB Length = 284 Score = 29.6 bits (65), Expect = 5.3, Method: Compositional matrix adjust. Identities = 13/40 (32%), Positives = 22/40 (55%) Query: 44 ETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTW 83 + V++G G G+S AY ++K V ++E+S G W Sbjct: 41 DVVVVGAGSAGLSAAYEISKNPNVQVAIIEQSVSPGGGAW 80 >5JMD-A nrPDB Length = 655 Score = 29.6 bits (65), Expect = 5.7, Method: Compositional matrix adjust. Identities = 12/33 (36%), Positives = 17/33 (51%) Query: 484 EQPHWFYKPGQDTQYRPSFRRTNWFRPVGSEYK 516 E +W Y P +D + R R WF P+G Y+ Sbjct: 100 EDINWQYWPVKDNELRWQLHRHKWFTPMGKAYR 132 >5Z9A-A nrPDB Length = 363 Score = 29.6 bits (65), Expect = 5.9, Method: Compositional matrix adjust. Identities = 15/50 (30%), Positives = 27/50 (54%), Gaps = 4/50 (8%) Query: 308 QEKMKLQASWVAHGVPPGFGKELFESDLDRITEHVEAAMEMVPVLKKADI 357 Q+ + + + VA GVPPG G+ +F DR+ + A+ + +K +I Sbjct: 199 QDSVGAKITVVAEGVPPGLGEPIF----DRLDAELAHALMSINAVKGVEI 244 >3R9U-A nrPDB Length = 315 Score = 29.3 bits (64), Expect = 7.2, Method: Compositional matrix adjust. Identities = 12/31 (38%), Positives = 20/31 (64%) Query: 44 ETVIIGGGCVGVSLAYHLAKAGMRDVVLLEK 74 + IIGGG G+S + + G+++VV+ EK Sbjct: 6 DVAIIGGGPAGLSAGLYATRGGLKNVVMFEK 36 >1REO-A nrPDB Length = 486 Score = 29.3 bits (64), Expect = 7.2, Method: Compositional matrix adjust. Identities = 16/35 (45%), Positives = 22/35 (62%), Gaps = 1/35 (2%) Query: 46 VIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAG 80 V++G G G+S AY L+ AG + V +LE SE G Sbjct: 37 VVVGAGMSGLSAAYVLSGAGHQ-VTVLEASERAGG 70 >4N9X-A nrPDB Length = 411 Score = 28.9 bits (63), Expect = 8.8, Method: Compositional matrix adjust. Identities = 15/31 (48%), Positives = 22/31 (70%), Gaps = 1/31 (3%) Query: 44 ETVIIGGGCVGVSLAYHLAKAGMRDVVLLEK 74 + VI GGG VG++LA L +G+R + +LEK Sbjct: 5 DVVIAGGGMVGLALACGLQGSGLR-IAVLEK 34 >6BRD-A nrPDB Length = 476 Score = 28.9 bits (63), Expect = 9.6, Method: Compositional matrix adjust. Identities = 45/159 (28%), Positives = 69/159 (43%), Gaps = 26/159 (16%) Query: 44 ETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKIHY 103 + +++GGG G+ LA L G+R +VL +++E T S G++++ I Sbjct: 3 DVIVVGGGPTGLMLAGELRLHGVRVLVLEKETEPTRQSRAQ----------GLHVRSIEV 52 Query: 104 DSIK-LYERLEE--ETGQVVGFHQPGSIRLATT-PERVDEFKYQMTRTNWHATEQYIIEP 159 + + L ER E T V GF LAT+ PER+D + TEQ + Sbjct: 53 MAQRGLLERFLERGHTVAVGGFFAG----LATSWPERLDTAHSYVLAVPQVITEQLL--A 106 Query: 160 EKIHELFPLLNMDKILAGLYNPGDGHIDPYSLTMALATG 198 E L + + L GL DG +T+ LA G Sbjct: 107 EHATALGAEIRRGRALVGLRQDEDG------VTVDLADG 139 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 4P9S-A nrPDB 1203 0.0 5L46-A nrPDB 1171 0.0 1PJ5-A nrPDB 810 0.0 1YX2-A nrPDB 403 e-112 1WOR-A nrPDB 389 e-108 1V5V-A nrPDB 388 e-108 2GAG-B nrPDB 386 e-107 3GIR-A nrPDB 356 4e-98 1WSR-A nrPDB 354 1e-97 3BHF-A nrPDB 351 1e-96 3AD9-B nrPDB 350 1e-96 3A8J-A nrPDB 345 4e-95 2GAG-A nrPDB 333 2e-91 1ZOV-A nrPDB 331 6e-91 1VRQ-A nrPDB 329 2e-90 3TFJ-A nrPDB 329 4e-90 1NG3-A nrPDB 302 6e-82 3SM8-A nrPDB 292 5e-79 4YSH-A nrPDB 253 3e-67 Sequences not found previously or not previously below threshold: 2UZZ-A nrPDB 186 3e-47 5X1I-A nrPDB 109 6e-24 5XAO-A nrPDB 94 2e-19 3VQR-A nrPDB 81 2e-15 3PVC-A nrPDB 56 8e-08 3PS9-A nrPDB 56 8e-08 5EZ7-A nrPDB 54 3e-07 5KOX-A nrPDB 54 3e-07 3ATQ-A nrPDB 52 1e-06 1QO8-A nrPDB 51 2e-06 3CUK-A nrPDB 50 3e-06 2RGO-A nrPDB 50 5e-06 2RGH-A nrPDB 50 6e-06 1KNR-A nrPDB 49 7e-06 1VE9-A nrPDB 47 4e-05 1RP0-A nrPDB 47 5e-05 3DA1-A nrPDB 46 6e-05 5NCC-A nrPDB 46 7e-05 3ISH-A nrPDB 44 2e-04 3R9U-A nrPDB 44 3e-04 1D4E-A nrPDB 44 3e-04 4DGK-A nrPDB 43 5e-04 5KXJ-A nrPDB 42 7e-04 6BRD-A nrPDB 42 0.001 4C5O-A nrPDB 42 0.001 4REP-A nrPDB 42 0.001 3FPZ-A nrPDB 42 0.001 1C0L-A nrPDB 41 0.002 1F8S-A nrPDB 41 0.002 4BK3-A nrPDB 41 0.002 5MOG-A nrPDB 41 0.003 2BXR-A nrPDB 39 0.006 4Y4M-A nrPDB 39 0.006 1NAA-A nrPDB 39 0.007 5MJK-A nrPDB 39 0.007 5UWY-A nrPDB 39 0.008 4UIR-A nrPDB 39 0.008 1O5W-A nrPDB 39 0.010 3KVE-A nrPDB 39 0.012 2JB2-A nrPDB 39 0.013 3ABT-A nrPDB 38 0.015 3II4-A nrPDB 38 0.015 2CVJ-A nrPDB 38 0.020 2VVL-G nrPDB 37 0.024 5L3D-A nrPDB 37 0.028 3WE0-A nrPDB 37 0.030 1MDA-H nrPDB 37 0.034 5ZYN-B nrPDB 37 0.034 1REO-A nrPDB 37 0.036 1SEZ-A nrPDB 37 0.037 2IVE-A nrPDB 37 0.038 3JSK-A nrPDB 37 0.040 3IHG-A nrPDB 37 0.043 1JWB-B nrPDB 37 0.044 4EIQ-A nrPDB 37 0.044 3MJ4-A nrPDB 37 0.045 3UP5-A nrPDB 37 0.047 4K2X-A nrPDB 37 0.048 3L1R-A nrPDB 37 0.048 4JNQ-A nrPDB 37 0.049 5TUK-A nrPDB 36 0.057 4B1B-A nrPDB 36 0.063 3BI4-A nrPDB 36 0.064 4RPJ-A nrPDB 36 0.069 4IV9-A nrPDB 36 0.069 3NK2-X nrPDB 36 0.077 6J0Z-C nrPDB 36 0.081 4Y4N-A nrPDB 36 0.087 6CR0-A nrPDB 36 0.10 3RHA-A nrPDB 35 0.11 4N9X-A nrPDB 35 0.13 4USR-A nrPDB 35 0.13 5EVY-X nrPDB 35 0.15 5TUM-A nrPDB 35 0.15 3CGD-A nrPDB 35 0.15 4MOP-A nrPDB 34 0.20 3LOV-A nrPDB 34 0.23 6N7F-A nrPDB 34 0.23 4IA5-A nrPDB 34 0.25 2Q7V-A nrPDB 34 0.31 2CUL-A nrPDB 34 0.35 4OVI-A nrPDB 34 0.36 1FEC-A nrPDB 34 0.38 1V59-A nrPDB 33 0.46 3VH2-A nrPDB 33 0.47 3T7E-A nrPDB 33 0.47 4Z25-A nrPDB 33 0.47 1KSU-A nrPDB 33 0.47 4OEN-A nrPDB 33 0.54 3LXD-A nrPDB 33 0.59 5EQD-A nrPDB 33 0.61 4X4J-A nrPDB 33 0.62 4ZN0-A nrPDB 33 0.65 1ZFN-A nrPDB 33 0.65 1UXJ-A nrPDB 33 0.69 2NVK-X nrPDB 33 0.70 3WSV-A nrPDB 32 0.78 4NQW-A nrPDB 32 0.82 4IVM-B nrPDB 32 0.82 4NTC-A nrPDB 32 0.87 5Z70-A nrPDB 32 0.95 6C6P-A nrPDB 32 0.96 3Q6J-A nrPDB 32 0.97 6QE4-A nrPDB 32 0.99 4YNU-A nrPDB 32 1.0 3LZX-A nrPDB 32 1.0 4F5M-A nrPDB 32 1.1 2ZBW-A nrPDB 32 1.2 1I8T-A nrPDB 32 1.3 4MO2-B nrPDB 32 1.3 6GAS-A nrPDB 32 1.3 1MAF-H nrPDB 32 1.4 3RED-A nrPDB 32 1.5 5BR7-A nrPDB 32 1.6 1DOD-A nrPDB 31 1.7 2D3L-A nrPDB 31 1.7 1ZDL-A nrPDB 31 1.8 2HQM-A nrPDB 31 1.8 4UDQ-A nrPDB 31 1.9 4AP1-A nrPDB 31 1.9 1CSN-A nrPDB 31 2.0 3RP7-A nrPDB 31 2.2 3GDN-A nrPDB 31 2.3 2X3N-A nrPDB 31 2.3 3B40-A nrPDB 30 3.8 4HA6-A nrPDB 30 4.0 2EPJ-A nrPDB 29 7.5 6AH0-2 nrPDB 29 8.2 5W1J-A nrPDB 29 8.5 >4P9S-A nrPDB Length = 848 Score = 1203 bits (3112), Expect = 0.0, Method: Composition-based stats. Identities = 830/836 (99%), Positives = 833/836 (99%) Query: 22 SSAGLREGQESPPSPPEWKDRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGS 81 SSAGLREGQESPPSPPEWKDRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGS Sbjct: 3 SSAGLREGQESPPSPPEWKDRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGS 62 Query: 82 TWHAAGLTTYFHPGINLKKIHYDSIKLYERLEEETGQVVGFHQPGSIRLATTPERVDEFK 141 TWHAAGLTTYFHPGINLKKIHYDSIKLYERLEEETGQVVGFHQPGSIRLATTPERVDEFK Sbjct: 63 TWHAAGLTTYFHPGINLKKIHYDSIKLYERLEEETGQVVGFHQPGSIRLATTPERVDEFK 122 Query: 142 YQMTRTNWHATEQYIIEPEKIHELFPLLNMDKILAGLYNPGDGHIDPYSLTMALATGARK 201 YQMTRTNWHATEQYIIEPEKIHELFPLLNMDKILAGLYNPGDGHIDPYSLTMALATGARK Sbjct: 123 YQMTRTNWHATEQYIIEPEKIHELFPLLNMDKILAGLYNPGDGHIDPYSLTMALATGARK 182 Query: 202 YGVLLKYPAPVTSLKPRPDGTWDVETPQGSVRANRIVNAAGFWAREVGKMIGLDHPLIPV 261 YG LLKYPAPVTSLKPRPDGTWDVETPQGSVRANRIVNAAGFWAREVGKMIGLDHPLIPV Sbjct: 183 YGALLKYPAPVTSLKPRPDGTWDVETPQGSVRANRIVNAAGFWAREVGKMIGLDHPLIPV 242 Query: 262 QHQYVVTSTIPEVKALKRELPVLRDLEGSYYLRQERDGLLFGPYESQEKMKLQASWVAHG 321 QHQYV+TSTIPEVKALKRELPVLRDLEGSYYLRQERDGLLFGPYESQEKMKLQASWVAHG Sbjct: 243 QHQYVITSTIPEVKALKRELPVLRDLEGSYYLRQERDGLLFGPYESQEKMKLQASWVAHG 302 Query: 322 VPPGFGKELFESDLDRITEHVEAAMEMVPVLKKADIINIVNGPITYSPDILPMVGPHQGV 381 VPPGFGKELFESDLDRITEHVEAAMEMVPVLKKADIINIVNGPITYSPDILPMVGPHQGV Sbjct: 303 VPPGFGKELFESDLDRITEHVEAAMEMVPVLKKADIINIVNGPITYSPDILPMVGPHQGV 362 Query: 382 RNYWVAIGFGYGIIHAGGVGKYLSDWILHGEPPFDLIELDPNRYGKWTTTQYTEAKARES 441 RNYWVAIGFGYGIIHAGGVG YLSDWILHGEPPFDLIELDPNRYGKWTTTQYTEAKARES Sbjct: 363 RNYWVAIGFGYGIIHAGGVGTYLSDWILHGEPPFDLIELDPNRYGKWTTTQYTEAKARES 422 Query: 442 YGFNNIVGYPKEERFAGRPTQRVSGLYKILESKCSMGFHAGWEQPHWFYKPGQDTQYRPS 501 YGFNNIVGYPKEERFAGRPTQRVSGLYKILESKCSMGFHAGWEQPHWFYKPGQDTQYRPS Sbjct: 423 YGFNNIVGYPKEERFAGRPTQRVSGLYKILESKCSMGFHAGWEQPHWFYKPGQDTQYRPS 482 Query: 502 FRRTNWFRPVGSEYKQVMQRVGVIDLSPFGKFNIKGQDSTQLLDHLCANVIPKVGFTNIS 561 FRRTNWF PVGSEYKQVMQRVGVIDLSPFGKFNIKGQDSTQLLDHLCANVIPKVGFTNIS Sbjct: 483 FRRTNWFEPVGSEYKQVMQRVGVIDLSPFGKFNIKGQDSTQLLDHLCANVIPKVGFTNIS 542 Query: 562 HMLTPRGRVYAELTVSHQSPGEFLLITGSGSELHDLRWIEEAAVRGGYDVEIRNITDELG 621 HMLTPRGRVYAELTVSHQSPGEFLLITGSGSELHDLRWIEEAAVRGGYDVEIRNITDELG Sbjct: 543 HMLTPRGRVYAELTVSHQSPGEFLLITGSGSELHDLRWIEEAAVRGGYDVEIRNITDELG 602 Query: 622 VLGVAGPYARRVLQKLTSEDLSDDVFKFLQTKSLKISDIPVTAIRISYTGELGWELYHRR 681 VLGVAGPYARRVLQKLTSEDLSDDVFKFLQTKSLKISDIPVTAIRISYTGELGWELYHRR Sbjct: 603 VLGVAGPYARRVLQKLTSEDLSDDVFKFLQTKSLKISDIPVTAIRISYTGELGWELYHRR 662 Query: 682 EDSAALYERIMNAGQEEGIDNFGTYALNALRLEKAFRAWGSEMNCDTNPLEAGLDYFIKL 741 EDSAALYERIMNAGQEEGIDNFGTYALNALRLEKAFRAWGSEMNCDTNPLEAGLDYFIKL Sbjct: 663 EDSAALYERIMNAGQEEGIDNFGTYALNALRLEKAFRAWGSEMNCDTNPLEAGLDYFIKL 722 Query: 742 NKPADFTGKQALKQIKAKGLKRRLVCLTLATDDVDPEGNESVWYKGKVIGNTTSGSYSYS 801 NKPA+FTGKQALKQIKAKGLKRRLVCLTLATD+VDPEGNESVWYKGKVIGNTTSGSYSYS Sbjct: 723 NKPANFTGKQALKQIKAKGLKRRLVCLTLATDNVDPEGNESVWYKGKVIGNTTSGSYSYS 782 Query: 802 IQKSLAFAYVPVELSEVGQQVEVELLGKNYPATIIQEPLVLTEPTRTRLQKDGRKS 857 IQKSLAFAYVPVELSEVGQQVEVELLGKNYPATIIQEPLVLTEPTRTRLQKDGRKS Sbjct: 783 IQKSLAFAYVPVELSEVGQQVEVELLGKNYPATIIQEPLVLTEPTRTRLQKDGRKS 838 >5L46-A nrPDB Length = 841 Score = 1171 bits (3029), Expect = 0.0, Method: Composition-based stats. Identities = 769/832 (92%), Positives = 798/832 (95%), Gaps = 2/832 (0%) Query: 27 REGQESPPSPPE--WKDRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWH 84 REG+E PP E WKDRAETVIIGGGCVGVSLAYHLAKAGM+DVVLLEKSELTAGSTWH Sbjct: 5 REGEEKPPLSAETQWKDRAETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGSTWH 64 Query: 85 AAGLTTYFHPGINLKKIHYDSIKLYERLEEETGQVVGFHQPGSIRLATTPERVDEFKYQM 144 AAGLTTYFHPGINLKKIHYDSIKLYE+LEEETGQVVGFHQPGSIRLATTP RVDEFKYQM Sbjct: 65 AAGLTTYFHPGINLKKIHYDSIKLYEKLEEETGQVVGFHQPGSIRLATTPVRVDEFKYQM 124 Query: 145 TRTNWHATEQYIIEPEKIHELFPLLNMDKILAGLYNPGDGHIDPYSLTMALATGARKYGV 204 TRT WHATEQY+IEPEKI E+FPLLNM+K+LAGLYNPGDGHIDPYSLTMALA GARK G Sbjct: 125 TRTGWHATEQYLIEPEKIQEMFPLLNMNKVLAGLYNPGDGHIDPYSLTMALAAGARKCGA 184 Query: 205 LLKYPAPVTSLKPRPDGTWDVETPQGSVRANRIVNAAGFWAREVGKMIGLDHPLIPVQHQ 264 LLKYPAPVTSLK R DGTWDVETPQGS+RANRIVNAAGFWAREVGKMIGL+HPLIPVQHQ Sbjct: 185 LLKYPAPVTSLKARSDGTWDVETPQGSMRANRIVNAAGFWAREVGKMIGLEHPLIPVQHQ 244 Query: 265 YVVTSTIPEVKALKRELPVLRDLEGSYYLRQERDGLLFGPYESQEKMKLQASWVAHGVPP 324 YVVTSTIPEVKALKRELPVLRDLEGSYYLRQERDGLLFGPYESQEKMK+Q SWV +GVPP Sbjct: 245 YVVTSTIPEVKALKRELPVLRDLEGSYYLRQERDGLLFGPYESQEKMKVQDSWVTNGVPP 304 Query: 325 GFGKELFESDLDRITEHVEAAMEMVPVLKKADIINIVNGPITYSPDILPMVGPHQGVRNY 384 GFGKELFESDLDRI EH++AAMEMVPVLKKADIIN+VNGPITYSPDILPMVGPHQGVRNY Sbjct: 305 GFGKELFESDLDRIMEHIKAAMEMVPVLKKADIINVVNGPITYSPDILPMVGPHQGVRNY 364 Query: 385 WVAIGFGYGIIHAGGVGKYLSDWILHGEPPFDLIELDPNRYGKWTTTQYTEAKARESYGF 444 WVAIGFGYGIIHAGGVGKYLSDWILHGEPPFDLIELDPNRYGKWTTTQYTEAKARESYGF Sbjct: 365 WVAIGFGYGIIHAGGVGKYLSDWILHGEPPFDLIELDPNRYGKWTTTQYTEAKARESYGF 424 Query: 445 NNIVGYPKEERFAGRPTQRVSGLYKILESKCSMGFHAGWEQPHWFYKPGQDTQYRPSFRR 504 NNIVGYPKEERFAGRPTQRVSGLY+ LESKCSMGFHAGWEQPHWFYKPGQDTQYRPSFRR Sbjct: 425 NNIVGYPKEERFAGRPTQRVSGLYQRLESKCSMGFHAGWEQPHWFYKPGQDTQYRPSFRR 484 Query: 505 TNWFRPVGSEYKQVMQRVGVIDLSPFGKFNIKGQDSTQLLDHLCANVIPKVGFTNISHML 564 TNWF PVGSEYKQVMQRV V DLSPFGKFNIKGQDS +LLDHL ANVIPKVGFTNISHML Sbjct: 485 TNWFEPVGSEYKQVMQRVAVTDLSPFGKFNIKGQDSIRLLDHLFANVIPKVGFTNISHML 544 Query: 565 TPRGRVYAELTVSHQSPGEFLLITGSGSELHDLRWIEEAAVRGGYDVEIRNITDELGVLG 624 TP+GRVYAELTVSHQSPGEFLLITGSGSELHDLRWIEE AV+GGYDVEI+NITDELGVLG Sbjct: 545 TPKGRVYAELTVSHQSPGEFLLITGSGSELHDLRWIEEEAVKGGYDVEIKNITDELGVLG 604 Query: 625 VAGPYARRVLQKLTSEDLSDDVFKFLQTKSLKISDIPVTAIRISYTGELGWELYHRREDS 684 VAGP AR+VLQKLTSEDLSDDVFKFLQTKSLK+S+IPVTAIRISYTGELGWELYHRREDS Sbjct: 605 VAGPQARKVLQKLTSEDLSDDVFKFLQTKSLKVSNIPVTAIRISYTGELGWELYHRREDS 664 Query: 685 AALYERIMNAGQEEGIDNFGTYALNALRLEKAFRAWGSEMNCDTNPLEAGLDYFIKLNKP 744 ALY+ IMNAGQEEGIDNFGTYA+NALRLEKAFRAWG EMNCDTNPLEAGL+YF+KLNKP Sbjct: 665 VALYDAIMNAGQEEGIDNFGTYAMNALRLEKAFRAWGLEMNCDTNPLEAGLEYFVKLNKP 724 Query: 745 ADFTGKQALKQIKAKGLKRRLVCLTLATDDVDPEGNESVWYKGKVIGNTTSGSYSYSIQK 804 ADF GKQALKQIKAKGLKRRLVCLTLATDDVDPEGNES+WY GKV+GNTTSGSYSYSIQK Sbjct: 725 ADFIGKQALKQIKAKGLKRRLVCLTLATDDVDPEGNESIWYNGKVVGNTTSGSYSYSIQK 784 Query: 805 SLAFAYVPVELSEVGQQVEVELLGKNYPATIIQEPLVLTEPTRTRLQKDGRK 856 SLAFAYVPV+LSEVGQQVEVELLGKNYPA IIQEPLVLTEPTR RLQK G K Sbjct: 785 SLAFAYVPVQLSEVGQQVEVELLGKNYPAVIIQEPLVLTEPTRNRLQKKGGK 836 >1PJ5-A nrPDB Length = 830 Score = 810 bits (2091), Expect = 0.0, Method: Composition-based stats. Identities = 241/837 (28%), Positives = 404/837 (48%), Gaps = 44/837 (5%) Query: 45 TVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSEL--TAGSTWHAAGLTTYFHPGINLKKIH 102 VIIG G VG +LA L G ++ +L++ L GST HA GL +P + Sbjct: 7 IVIIGAGIVGTNLADELVTRGWNNITVLDQGPLNMPGGSTSHAPGLVFQTNPSKTMASFA 66 Query: 103 YDSIKLYERLEEETGQVVGFHQPGSIRLATTPERVDEFKYQMTRTNWHATEQYIIEPEKI 162 +++ L E+ V F+Q G + +ATT R+ + K ++ E ++ P + Sbjct: 67 KYTVEKLLSLTED--GVSCFNQVGGLEVATTETRLADLKRKLGYAAAWGIEGRLLSPAEC 124 Query: 163 HELFPLLNMDKILAGLYNPGDGHIDPYSLTMALATGARKYGVLLKYPAPVTSLKPRPDGT 222 EL+PLL+ + IL GL+ P DG L GV + VT ++ Sbjct: 125 QELYPLLDGENILGGLHVPSDGLASAARAVQLLIKRTESAGVTYRGSTTVTGIEQSGGRV 184 Query: 223 WDVETPQGSVRANRIVNAAGFWAREVGKMIGLDHPLIPVQHQYVVTSTIPEVKALKRE-- 280 V+T G + A+ +V+ AGFW ++G MIG+ PL+P+ HQYV T+ +P + + Sbjct: 185 TGVQTADGVIPADIVVSCAGFWGAKIGAMIGMAVPLLPLAHQYVKTTPVPAQQGRNDQPN 244 Query: 281 ---LPVLRDLEGSYYLRQERDGLLFGPYESQEKMKLQASWVAHGVPPGFGKELFESDLDR 337 LP+LR + Y R+ D G Y + M + + P + S LD Sbjct: 245 GARLPILRHQDQDLYYREHGDRYGIGSY-AHRPMPVDVDTLGAYAPETVSEHHMPSRLDF 303 Query: 338 ITEHV----EAAMEMVPVLKKADIINIVNGPITYSPDILPMVGPHQGVRNYWVAIGFGYG 393 E EA +++P L ++I + NG +++PD P++G + + ++VA Sbjct: 304 TLEDFLPAWEATKQLLPALADSEIEDGFNGIFSFTPDGGPLLGESKELDGFYVAEAVW-- 361 Query: 394 IIHAGGVGKYLSDWILHGEPPFDLIELDPNRYGKWTTT-QYTEAKARESYGFNNIVGYPK 452 + H+ GV K +++ + G DL E D R+ T +Y +++++ V +P Sbjct: 362 VTHSAGVAKAMAELLTTGRSETDLGECDITRFEDVQLTPEYVSETSQQNFVEIYDVLHPL 421 Query: 453 EERFAGRPTQRVSGLYKILESKCSMGFHA-GWEQPHWFYKPGQDTQYRPSFRRTNWFRPV 511 + R + R RVS + + + A GWE+P+WF + P+ W P Sbjct: 422 QPRLSPR-NLRVSPFHARHKELGAFFLEAGGWERPYWFEANAALLKEMPA----EWLPPA 476 Query: 512 GS-------------EYKQVMQRVGVIDLSPFGKFNIKGQDSTQLLDHLCANVIP-KVGF 557 E + V + D++P + + G + +LL L + K G Sbjct: 477 RDAWSGMFSSPIAAAEAWKTRTAVAMYDMTPLKRLEVSGPGALKLLQELTTADLAKKPGA 536 Query: 558 TNISHMLTPRGRVYAELTVSHQSPGEFLLITGSGSELHDLRWIEEAAVRGGYD---VEIR 614 + +L G V +++TV+ S F L + + G V++R Sbjct: 537 VTYTLLLDHAGGVRSDITVARLSEDTFQLGANGNIDTAYFERAARHQTQSGSATDWVQVR 596 Query: 615 NITDELGVLGVAGPYARRVLQKLTSEDLSDDVFKFLQTKSLKISDIPVTAIRISYTGELG 674 + T +G+ GP AR ++ K++ +D ++D K+ + K++ I IPVTA+R+SY GELG Sbjct: 597 DTTGGTCCIGLWGPLARDLVSKVSDDDFTNDGLKYFRAKNVVIGGIPVTAMRLSYVGELG 656 Query: 675 WELYHRREDSAALYERIMNAGQEEGIDNFGTYALNALRLEKAFRAWGSEMNCDTNPLEAG 734 WELY ++ L++ + AGQ G+ G A ++LRLEK +R+WG++M + +P EAG Sbjct: 657 WELYTSADNGQRLWDALWQAGQPFGVIAAGRAAFSSLRLEKGYRSWGTDMTTEHDPFEAG 716 Query: 735 LDYFIKLNKPADFTGKQALKQIKAKGLKRRLVCLTLATDDVDPEGNESVWYKGKVIGNTT 794 L + +K+ K + F GK AL+ + RRL CLT+ G E V+YK + +G T Sbjct: 717 LGFAVKMAKES-FIGKGALEGRTEEASARRLRCLTIDDGRSIVLGKEPVFYKEQAVGYVT 775 Query: 795 SGSYSYSIQKSLAFAYVPVELSEVGQQVEVELLGKNYPATIIQEPLVLTEPTRTRLQ 851 S +Y Y++ K +A++Y+P +S VG V++E G+ AT+ ++PL +P TRL+ Sbjct: 776 SAAYGYTVAKPIAYSYLPGTVS-VGDSVDIEYFGRRITATVTEDPLY--DPKMTRLR 829 >1YX2-A nrPDB Length = 365 Score = 403 bits (1035), Expect = e-112, Method: Composition-based stats. Identities = 110/384 (28%), Positives = 180/384 (46%), Gaps = 29/384 (7%) Query: 462 QRVSGLYKILES-KCSMGFHAGWEQPHWFYKPGQDTQYRPSFRRTNWFRPVGSEYKQVMQ 520 + + L+ + + GWE P F + E++ V Sbjct: 5 LKRTPLFDLYKEYGGKTIDFGGWELPVQ-------------------FSSIKKEHEAVRT 45 Query: 521 RVGVIDLSPFGKFNIKGQDSTQLLDHLCANVIPK--VGFTNISHMLTPRGRVYAELTVSH 578 G+ D+S G+ + G DS L L N + G + M P G +L + Sbjct: 46 AAGLFDVSHMGEVEVSGNDSLSFLQRLMTNDVSALTPGRAQYTAMCYPDGGTVDDLLIYQ 105 Query: 579 QSPGEFLLITGSGSELHDLRWIEEAAVRGGYDVEIRNITDELGVLGVAGPYARRVLQKLT 638 + +LL+ + + DL W++E A DV+I N +D++ +L V GP A +L+ LT Sbjct: 106 KGENRYLLVINASNIDKDLAWMKEHAAG---DVQIDNQSDQIALLAVQGPKAEAILKNLT 162 Query: 639 SEDLSD-DVFKFLQTKSLKISDIPVTAIRISYTGELGWELYHRREDSAALYERIMNAGQE 697 D+S F F+ IS R YTGE G+E+Y R +D+ ++++I++AG Sbjct: 163 DADVSALKPFAFIDEAD--ISGRKALISRTGYTGEDGYEIYCRSDDAMHIWKKIIDAGDA 220 Query: 698 EGIDNFGTYALNALRLEKAFRAWGSEMNCDTNPLEAGLDYFIKLNKPADFTGKQALKQIK 757 G+ G A + LR E +G E+ D P+EAG+ + +K K +DF GK L + K Sbjct: 221 YGLIPCGLGARDTLRFEANIPLYGQELTRDITPIEAGIGFAVKHKKESDFFGKSVLSEQK 280 Query: 758 AKGLKRRLVCLTLATDDVDPEGNESVWYKGKVIGNTTSGSYSYSIQKSLAFAYVPVELSE 817 G KR+LV L + + G E V+ GK +G T+G+ S ++ K++ A + E SE Sbjct: 281 ENGAKRKLVGLEMIEKGIPRHGYE-VFQNGKSVGKVTTGTQSPTLGKNVGLALIDSETSE 339 Query: 818 VGQQVEVELLGKNYPATIIQEPLV 841 +G V+VE+ K A +++ P Sbjct: 340 IGTVVDVEIRKKLVKAKVVKTPFY 363 >1WOR-A nrPDB Length = 364 Score = 389 bits (998), Expect = e-108, Method: Composition-based stats. Identities = 114/386 (29%), Positives = 191/386 (49%), Gaps = 35/386 (9%) Query: 462 QRVSGLYKILESKCSMGFHAGWEQPHWFYKPGQDTQYRPSFRRTNWFRPVGSEYKQVMQR 521 +R K +E M AGWE P ++ + E V + Sbjct: 2 KRTPLFEKHVELGAKMVDFAGWEMPLYY-------------------TSIFEEVMAVRKS 42 Query: 522 VGVIDLSPFGKFNIKGQDSTQLLDHLCANVIPKV--GFTNISHMLTPRGRVYAELTVSHQ 579 VG+ D+S G+F +KG ++ +D L N + G S M G + +L V Sbjct: 43 VGMFDVSHMGEFLVKGPEAVSFIDFLITNDFSSLPDGKAIYSVMCNENGGIIDDLVVYKV 102 Query: 580 SPGEFLLITGSGSELHDLRWIEEAAVRGGYDVEIRNITDELGVLGVAGPYARRVLQKLTS 639 SP E L++ + + D WI+ + +DVE+ NI+D ++ GP A+ LQ+L Sbjct: 103 SPDEALMVVNAANIEKDFNWIKSHS--KNFDVEVSNISDTTALIAFQGPKAQETLQELV- 159 Query: 640 EDLSDDVFKFLQTKSLKISDIPVTAIRISYTGELGWELYHRREDSAALYERIMNAGQEEG 699 ED +++ + KS+ ++ + R YTGE G+EL +++ +++ +MN ++ Sbjct: 160 EDGLEEIAYYSFRKSI-VAGVETLVSRTGYTGEDGFELMLEAKNAPKVWDALMNLLRKID 218 Query: 700 IDNFGTYALNALRLEKAFRAWGSEMNCDTNPLEAGLDYFIKLNKPADFTGKQALKQIKAK 759 G A + RLE + +G +M+ +TNP E GL + +KLNK DF GK+AL + K K Sbjct: 219 GRPAGLGARDVCRLEATYLLYGQDMDENTNPFEVGLSWVVKLNK--DFVGKEALLKAKEK 276 Query: 760 GLKRRLVCLTLATDDVDPEGNESVWYKGKVIGNTTSGSYSYSIQKSLAFAYVPVELSEVG 819 ++R+LV L L+ + +G E V G+ +G TSG++S ++ KS+A A V + ++G Sbjct: 277 -VERKLVALELSGKRIARKGYE-VLKNGERVGEITSGNFSPTLGKSIALALVSKSV-KIG 333 Query: 820 QQVEVELLGKNYPATIIQEPLVLTEP 845 Q LG +P + E LV+ +P Sbjct: 334 DQ-----LGVVFPGGKLVEALVVKKP 354 >1V5V-A nrPDB Length = 401 Score = 388 bits (995), Expect = e-108, Method: Composition-based stats. Identities = 107/421 (25%), Positives = 185/421 (43%), Gaps = 55/421 (13%) Query: 462 QRVSGLYKILESKCSMGFHAGWEQPHWFYKPGQDTQYRPSFRRTNWFRPVGSEYKQVMQR 521 +RV E + AGWE P W+ + E+ V Sbjct: 6 KRVHIFDWHKEHARKIEEFAGWEMPIWY-------------------SSIKEEHLAVRNA 46 Query: 522 VGVIDLSPFGKFNIKGQDSTQLLDHLCANVIPKVGF--TNISHMLTPRGRVYAELTVSHQ 579 VG+ D+S G+ +G+D+ + L ++ N I K + +L RG + E V + Sbjct: 47 VGIFDVSHMGEIVFRGKDALKFLQYVTTNDISKPPAISGTYTLVLNERGAIKDETLVFNM 106 Query: 580 SPGEFLLITGSGSELHDLRWIE----EAAVRGGYDVEIRNITDELGVLGVAGPYARRVLQ 635 E+L+I S + W D+EI T ++ + V GP AR + + Sbjct: 107 GNNEYLMICDSDAFEKLYAWFTYLKRTIEQFTKLDLEIELKTYDIAMFAVQGPKARDLAK 166 Query: 636 KLTSEDLSDDVFKFLQTKSLKISDIPVTAIRISYTGELGWELYHRR-------------- 681 L D+++ + Q + +++ I + R YTGE G+E+Y Sbjct: 167 DLFGIDINE--MWWFQARWVELDGIKMLLSRSGYTGENGFEVYIEDANPYHPDESKRGEP 224 Query: 682 EDSAALYERIMNAGQEEGIDNFGTYALNALRLEKAFRAWGSEMNC---------DTNPLE 732 E + ++ERI+ G++ GI G A + LRLE + +G+E + PL+ Sbjct: 225 EKALHVWERILEEGKKYGIKPCGLGARDTLRLEAGYTLYGNETKELQLLSTDIDEVTPLQ 284 Query: 733 AGLDYFIKLNKPADFTGKQALKQIKAKGLKRRLVCLTLATDDVDPEGNESVWYKGKVIGN 792 A L++ I +K DF GK AL + K +G+ R+LV + + EG + V+ G++IG Sbjct: 285 ANLEFAIYWDK--DFIGKDALLKQKERGVGRKLVHFKMIDKGIPREGYK-VYANGEMIGE 341 Query: 793 TTSGSYSYSIQKSLAFAYVPVELSEVGQQVEVELLGKNYPATIIQEPLVLTEPTRTRLQK 852 TSG+ S + + A+V E ++ G ++EVE+ G+ A + P +P + L + Sbjct: 342 VTSGTLSPLLNVGIGIAFVKEEYAKPGIEIEVEIRGQRKKAVTVTPPFY--DPKKYGLFR 399 Query: 853 D 853 + Sbjct: 400 E 400 >2GAG-B nrPDB Length = 405 Score = 386 bits (990), Expect = e-107, Method: Composition-based stats. Identities = 89/399 (22%), Positives = 160/399 (40%), Gaps = 33/399 (8%) Query: 37 PEWKDRAETVIIGGGCVGVSLAYHLAK-AGMRDVVLLEKSELTAGSTWHAAGLTTYFHPG 95 PE K + +I+GGG G++ AY LAK G+ +V +LEK L G+ + + Sbjct: 16 PEPKKSYDAIIVGGGGHGLATAYFLAKNHGITNVAVLEKGWLAGGNMARNTTIIRSNYLW 75 Query: 96 INLKKIHYDSIKLYERLEEETGQVVGFHQPGSIRLATTPERVDEFKYQMTRTNWHATEQY 155 I+ S+KL+E+L E+ F Q G + LA T V E ++ + + Sbjct: 76 DESAGIYEKSLKLWEQLPEDLEYDFLFSQRGVLNLAHTLGDVRESVRRVEANKLNGVDAE 135 Query: 156 IIEPEKIHELFPLLNMDK-----ILAGLYNPGDGHIDPYSLTMALATGARKYGVLLKYPA 210 ++P ++ E P++N ++ + P G + A A A + GV + Sbjct: 136 WLDPSQVKEACPIINTSDDIRYPVMGATWQPRAGIAKHDHVAWAFARKANEMGVDIIQNC 195 Query: 211 PVTSLKPRPDGTWDVETPQGSVRANRIVNAAGFWAREVGKMIGLDHPLIPVQHQYVVTST 270 VT + V+T +G++ A ++ A + + +M G + P+ Q +V+ Sbjct: 196 EVTGFIKDGEKVTGVKTTRGTIHAGKVALAGAGHSSVLAEMAGFELPIQSHPLQALVSEL 255 Query: 271 IPEVKALKRELPVLRDLEGSYYLRQERDGLLFGPYESQEKMKLQASWVAHGVPP--GFGK 328 V V+ Y+ Q G L + G+ G+G+ Sbjct: 256 FEPVHPT-----VVMSNHIHVYVSQAHKGELV---------------MGAGIDSYNGYGQ 295 Query: 329 ELFESDLDRITEHVEAAMEMVPVLKKADIINIVNGPITYSPDILPMVGPHQGVRNYWVAI 388 I E + AA+E+ P+ +A ++ G + + D P++ ++N +V Sbjct: 296 ---RGAFHVIQEQMAAAVELFPIFARAHVLRTWGGIVDTTMDASPIISK-TPIQNLYVNC 351 Query: 389 GFGYGIIHA-GGVGKYLSDWILHGEPPFDLIELDPNRYG 426 G+G G G G L+ I + EP R+ Sbjct: 352 GWGTGGFKGTPGAGFTLAHTIANDEPHELNKPFSLERFE 390 >3GIR-A nrPDB Length = 393 Score = 356 bits (912), Expect = 4e-98, Method: Composition-based stats. Identities = 95/386 (24%), Positives = 158/386 (40%), Gaps = 36/386 (9%) Query: 461 TQRVSGLYKILE-SKCSMGFHAGWEQPHWFYKPGQDTQYRPSFRRTNWFRPVGSEYKQVM 519 + + LY++ E + G AGW P + V E+ Sbjct: 32 SLKTLPLYELHEKAGAKFGAFAGWRMPLTYP------------------LGVLKEHLHTR 73 Query: 520 QRVGVIDLSPFGKFNIKGQDSTQLLDHL--CANVIPKVGFTNISHMLTPRGRVYAELTVS 577 G+ D+S ++G + + L + + K+G + S++L R + +L ++ Sbjct: 74 AHAGLFDISHMKLIAVEGPKAVEFLSYALPVDAALLKIGQSRYSYLLNERAGILDDLILT 133 Query: 578 HQSPGEFLLITGSGSELHDLRWIEEAAVRGGYDVEIRNITDELGVLGVAGPYARRVLQKL 637 + F+L+ +G+ D +E+ A + E + I E +L + GP A V L Sbjct: 134 RLAECRFMLVANAGNAQADFAELEKRA----FGFECQVIALERVLLALQGPQAAAV---L 186 Query: 638 TSEDLSDDVFKFLQTKSLKISDIPVTAIRISYTGELGWELYHRREDSAALYERIMNAGQE 697 L + F+Q + D R YTGE G+E+ + AL E+++ + Sbjct: 187 ADAGLPGNELLFMQGFEPQ-QDWF--ITRSGYTGEDGFEIALPIGCARALAEKLLGDSRV 243 Query: 698 EGIDNFGTYALNALRLEKAFRAWGSEMNCDTNPLEAGLDYFIKLN--KPADFTGKQALKQ 755 E + G A ++LRLE G+++ DT P++A L + + N + A F G +A + Sbjct: 244 EWV---GLAARDSLRLEAGLCLHGNDITPDTTPIDAALTWAVPKNVREKAQFYGAKAFLE 300 Query: 756 IKAKGLKRRLVCLTLATDDVDPEGNESVWYKGKVIGNTTSGSYSYSIQKSLAFAYVPVEL 815 KG R V L T G +G IG TSG + S +A YVPV Sbjct: 301 SLQKGPSRCRVGLKPQTRQPIRAGAVLFDNEGNRIGVVTSGGFGPSFDGPVAMGYVPVAW 360 Query: 816 SEVGQQVEVELLGKNYPATIIQEPLV 841 G +V EL GK ++ P V Sbjct: 361 KVEGTEVFTELRGKKIALSVHSLPFV 386 >1WSR-A nrPDB Length = 375 Score = 354 bits (907), Expect = 1e-97, Method: Composition-based stats. Identities = 100/395 (25%), Positives = 166/395 (42%), Gaps = 41/395 (10%) Query: 462 QRVSGLYK-ILESKCSMGFHAGWEQPHWFYKPGQDTQYRPSFRRTNWFRPVGSEYKQVMQ 520 R + LY L M AGW P QYR S + + Q Sbjct: 5 LRRTPLYDFHLAHGGKMVAFAGWSLP---------VQYRDSHTDS---------HLHTRQ 46 Query: 521 RVGVIDLSPFGKFNIKGQDSTQLLDHLCANVI--PKVGFTNISHMLTPRGRVYAELTVSH 578 + D+S + I G D +L++ L I + +S G + +L V++ Sbjct: 47 HCSLFDVSHMLQTKILGSDRVKLMESLVVGDIAELRPNQGTLSLFTNEAGGILDDLIVTN 106 Query: 579 QSPGEFLLITGSGSELHDLRWIEEAA---VRGGYDVEIRNITDELGVLGVAGPYARRVLQ 635 S G +++ +G DL +++ G DV + + + +L + GP A +VLQ Sbjct: 107 TSEGHLYVVSNAGCWEKDLALMQDKVRELQNQGRDVGLEVLDN--ALLALQGPTAAQVLQ 164 Query: 636 KLTSEDLSDDVFKFLQTKSLKISDIP-VTAIRISYTGELGWELYHRREDSAALYERIMNA 694 ++DL F+ + +++ + R YTGE G E+ + L I+ Sbjct: 165 AGVADDLRK--LPFMTSAVMEVFGVSGCRVTRCGYTGEDGVEISVPVAGAVHLATAILKN 222 Query: 695 GQEEGIDNFGTYALNALRLEKAFRAWGSEMNCDTNPLEAGLDYFIKLNKPA--DFTG-KQ 751 + + G A ++LRLE +G++++ T P+E L + + + A DF G K Sbjct: 223 PE---VKLAGLAARDSLRLEAGLCLYGNDIDEHTTPVEGSLSWTLGKRRRAAMDFPGAKV 279 Query: 752 ALKQIKAKGLKRR--LVCLTLATDDVDPEGNESVWYKGKVIGNTTSGSYSYSIQKSLAFA 809 + Q+K + +RR L+C P N +G IG TSG S S++K++A Sbjct: 280 IVPQLKGRVQRRRVGLMCEGAPMRAHSPILN----MEGTKIGTVTSGCPSPSLKKNVAMG 335 Query: 810 YVPVELSEVGQQVEVELLGKNYPATIIQEPLVLTE 844 YVP E S G + VE+ K A + + P V T Sbjct: 336 YVPCEYSRPGTMLLVEVRRKQQMAVVSKMPFVPTN 370 >3BHF-A nrPDB Length = 390 Score = 351 bits (899), Expect = 1e-96, Method: Composition-based stats. Identities = 81/391 (20%), Positives = 156/391 (39%), Gaps = 26/391 (6%) Query: 43 AETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAG--LTTYFHPGINLKK 100 + +++G G +G++ Y LAK G++ +++ + H + + G Sbjct: 5 FDVIVVGAGSMGMAAGYQLAKQGVKTLLVDAFDPPHTNGSHHGDTKIIRHAYGEGREYVP 64 Query: 101 IHYDSIKLYERLEEETGQVVGFHQPGSIRLATTPERVDEFKYQ-MTRTNWHATEQYIIEP 159 + S +L+ LE+ET + F + G L P+ F + M H+ ++E Sbjct: 65 LALRSQELWYELEKETHHKI-FTKTGV--LVFGPKGESAFVAETMEAAKEHSLTVDLLEG 121 Query: 160 EKIHELFPLLNMDKILAGLYNPGDGHIDPYSLTMALATGARKYGVLLKYPAPVTSLKPRP 219 ++I++ +P + + + ++ P G + + A A G + V P Sbjct: 122 DEINKRWPGITVPENYNAIFEPNSGVLFSENCIRAYRELAEARGAKVLTHTRVEDFDISP 181 Query: 220 DGTWDVETPQGSVRANRIVNAAGFWAREVGKMIGLDHPLIPVQHQYVVTSTIPEVKALKR 279 D + +ET GS A++++ + G W ++ + LD PL P + Q V E K Sbjct: 182 D-SVKIETANGSYTADKLIVSMGAWNSKLLSKLNLDIPLQPYR-QVVGFFESDESK---- 235 Query: 280 ELPVLRDLEGSYYLRQERDGLLFG-PYESQEKMKLQASWVAHGVPPGFGKE---LFESDL 335 D++ ++ + +G+ +G P +KL + P ++ D Sbjct: 236 ---YSNDIDFPGFMVEVPNGIYYGFPSFGGCGLKLGYHTFGQKIDPDTINREFGVYPEDE 292 Query: 336 DRITEHVEAAMEMVP-VLKKADIINIVNGPITYSPDILPMVGPHQGVRNYWVAIGF-GYG 393 + +E M LK+ + T + D ++ H N +A GF G+G Sbjct: 293 SNLRAFLEEYMPGANGELKRGAVCM-----YTKTLDEHFIIDLHPEHSNVVIAAGFSGHG 347 Query: 394 IIHAGGVGKYLSDWILHGEPPFDLIELDPNR 424 + GVG+ LS L G+ D+ NR Sbjct: 348 FKFSSGVGEVLSQLALTGKTEHDISIFSINR 378 >3AD9-B nrPDB Length = 404 Score = 350 bits (898), Expect = 1e-96, Method: Composition-based stats. Identities = 93/399 (23%), Positives = 162/399 (40%), Gaps = 33/399 (8%) Query: 37 PEWKDRAETVIIGGGCVGVSLAYHLAK-AGMRDVVLLEKSELTAGSTWHAAGLTTYFHPG 95 PE K + VI+GGG G++ AY+LAK G+ +V +LEK L G+ + + Sbjct: 15 PEPKKSYDVVIVGGGGHGLATAYYLAKNHGITNVAVLEKGWLAGGNMARNTTIIRSNYLW 74 Query: 96 INLKKIHYDSIKLYERLEEETGQVVGFHQPGSIRLATTPERVDEFKYQMTRTNWHATEQY 155 I+ S+KL+E L EE F Q G + LA T V E ++ ++ + Sbjct: 75 DESAGIYEKSLKLWEELPEELEYDFLFSQRGVLNLAHTLGDVRESIRRVEANKFNGVDAE 134 Query: 156 IIEPEKIHELFPLLNMDK-----ILAGLYNPGDGHIDPYSLTMALATGARKYGVLLKYPA 210 + PE++ E+ P++N ++ Y P G + A A A + GV + Sbjct: 135 WLTPEQVKEVCPIINTGDNIRYPVMGATYQPRAGIAKHDHVAWAFARKANEMGVDIIQNC 194 Query: 211 PVTSLKPRPDGTWDVETPQGSVRANRIVNAAGFWAREVGKMIGLDHPLIPVQHQYVVTST 270 VT + V+T +G++ A ++ A + + ++ G + P+ Q +V+ Sbjct: 195 EVTGFLKDGEKVTGVKTTRGTILAGKVALAGAGHSSVLAELAGFELPIQSHPLQALVSEL 254 Query: 271 IPEVKALKRELPVLRDLEGSYYLRQERDGLLFGPYESQEKMKLQASWVAHGVPP--GFGK 328 V V+ Y+ Q G L + G+ G+G+ Sbjct: 255 FEPVHPT-----VVMSNHIHVYVSQAHKGELV---------------MGAGIDSYNGYGQ 294 Query: 329 ELFESDLDRITEHVEAAMEMVPVLKKADIINIVNGPITYSPDILPMVGPHQGVRNYWVAI 388 I E + AA+E+ P+ +A ++ G + + D P++ ++N +V Sbjct: 295 ---RGAFHVIEEQMAAAVELFPIFARAHVLRTWGGIVDTTMDASPIISK-TPIQNLYVNC 350 Query: 389 GFGYGIIHA-GGVGKYLSDWILHGEPPFDLIELDPNRYG 426 G+G G G G L+ I H EP R+ Sbjct: 351 GWGTGGFKGTPGAGYTLAHTIAHDEPHKLNAPFALERFE 389 >3A8J-A nrPDB Length = 364 Score = 345 bits (885), Expect = 4e-95, Method: Composition-based stats. Identities = 94/392 (23%), Positives = 161/392 (41%), Gaps = 54/392 (13%) Query: 465 SGLYKILES-KCSMGFHAGWEQPHWFYKPGQDTQYRPSFRRTNWFRPVGSEYKQVMQRVG 523 + LY+ M GW P + E+ V G Sbjct: 5 TPLYEQHTLCGARMVDFHGWMMPLHY-------------------GSQIDEHHAVRTDAG 45 Query: 524 VIDLSPFGKFNIKGQDSTQLLDHLCANVIPKV---GFTNISHMLTPRGRVYAELTVSHQS 580 + D+S +++G + + L +L AN + K+ G S ML G V +L V + + Sbjct: 46 MFDVSHMTIVDLRGSRTREFLRYLLANDVAKLTKSGKALYSGMLNASGGVIDDLIVYYFT 105 Query: 581 PGEFLLITGSGSELHDLRWIEEAAVRGGYDVEIRNITDELGVLGVAGPYARRVLQKLTSE 640 F L+ S + DL WI + A G ++ +R D+L ++ V GP A+ L ++ Sbjct: 106 EDFFRLVVNSATREKDLSWITQHAEPFGIEITVR---DDLSMIAVQGPNAQAKAATLFND 162 Query: 641 DLSDDVFKFLQTKSLKISDIPVTAIRISYTGELGWELYHRREDSAALYERIMNAGQEEGI 700 V ++ D+ + YTGE G+E+ E +A + ++ AG + Sbjct: 163 AQRQAVEGMKPFFGVQAGDLFIATT--GYTGEAGYEIALPNEKAADFWRALVEAG----V 216 Query: 701 DNFGTYALNALRLEKAFRAWGSEMNCDTNPLEAGLDYFIKLN-KPADFTGKQALKQIKAK 759 G A + LRLE +G EM+ +PL A + + I DF G++AL+ + Sbjct: 217 KPCGLGARDTLRLEAGMNLYGQEMDETISPLAANMGWTIAWEPADRDFIGREALEVQREH 276 Query: 760 GLKRRLVCLTLATDDV----------DPEGNESVWYKGKVIGNTTSGSYSYSIQKSLAFA 809 G + +LV L + V D +GN+ G TSG++S ++ S+A A Sbjct: 277 GTE-KLVGLVMTEKGVLRNELPVRFTDAQGNQHE-------GIITSGTFSPTLGYSIALA 328 Query: 810 YVPVELSEVGQQVEVELLGKNYPATIIQEPLV 841 VP +G+ V++ + P + + V Sbjct: 329 RVP---EGIGETAIVQIRNREMPVKVTKPVFV 357 >2GAG-A nrPDB Length = 965 Score = 333 bits (854), Expect = 2e-91, Method: Composition-based stats. Identities = 100/408 (24%), Positives = 184/408 (45%), Gaps = 33/408 (8%) Query: 463 RVSGLYK-ILESKCSMGFHAGWEQPHWFYKPGQDTQYRPSFRRTNWFRPVGSEYKQVMQR 521 R++ ++ L W++P W+Y +T + +R E K V Sbjct: 575 RITAMHSWHLSHGAEFEDVGQWKRP-WYYPQAGETMDQAVYR----------ESKAVRDS 623 Query: 522 VGVIDLSPFGKFNIKGQDSTQLLDHLCAN--VIPKVGFTNISHMLTPRGRVYAELTVSHQ 579 VG++D + GK I+G+D+ + L+ + N KVG M G ++ + Sbjct: 624 VGMLDATTLGKIEIRGKDAAEFLNRIYTNGYTKLKVGMGRYGVMCKADGMIFDDGVTLRL 683 Query: 580 SPGEFLLITGSGSELHDLRWIEE--AAVRGGYDVEIRNITDELGVLGVAGPYARRVLQKL 637 + FLL T +G L W+EE DV ++T++L + V GP +R V+ KL Sbjct: 684 AEDRFLLHTTTGGAADVLDWLEEWLQTEWPDLDVTCTSVTEQLATVAVVGPRSRDVIAKL 743 Query: 638 TSE-DLSDDVFKFLQTKSLKI-SDIPVTAIRISYTGELGWELYHRREDSAALYERIMNAG 695 S D+S++ FKF+ K + + S I RIS++GEL +E+ ++E + AG Sbjct: 744 ASTVDVSNEGFKFMAFKDVVLDSGIEARISRISFSGELAFEIAVPAWHGLRVWEDVYAAG 803 Query: 696 QEEGIDNFGTYALNALRLEKAFRAWGSEMNCDTNPLEAGLDYFIKLNKPADFTGKQALKQ 755 +E I +GT ++ LR EK F G + + P +AG+++ + +K DF G ++ + Sbjct: 804 EEFNITPYGTETMHVLRAEKGFIIVGQDTDGTVTPQDAGMEWVV--SKLKDFIGNRSYSR 861 Query: 756 I-KAKGLKRRLVCLTLATDDV-DPEGNESVWYKG-------KVIGNTTSGSYSYSIQKSL 806 A+ +++LV + + PEG V + G TS S ++ ++ Sbjct: 862 ADNAREDRKQLVSVLPVDKSLRLPEGAALVASDALASEGITPMEGWVTSSYDSPNLGRTF 921 Query: 807 AFAYVPVELSEVGQQVEVELLGKNYPATIIQEPLVLTEPTRTRLQKDG 854 A + + +G+ ++ + + + + L +P +R +DG Sbjct: 922 GLALIKNGRNRIGEVLKTPVGDQLVDVVVSETVLY--DPEGSR--RDG 965 >1ZOV-A nrPDB Length = 386 Score = 331 bits (849), Expect = 6e-91, Method: Composition-based stats. Identities = 77/391 (19%), Positives = 153/391 (39%), Gaps = 26/391 (6%) Query: 43 AETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAG--LTTYFHPGINLKK 100 + +++G G +G++ Y+LAK G++ +++ + H + + G Sbjct: 4 FDVIVVGAGSMGMAAGYYLAKQGVKTLLVDSFDPPHTNGSHHGDTRIIRHAYGEGREYVP 63 Query: 101 IHYDSIKLYERLEEETGQVVGFHQPGSIRLATTPERVDEFKYQ-MTRTNWHATEQYIIEP 159 + +L+ LE+ET + F Q G L P+ F + M N H+ E + E Sbjct: 64 FALRAQELWYELEKETHHKI-FTQTGV--LVYGPKGGSAFVSETMEAANIHSLEHELFEG 120 Query: 160 EKIHELFPLLNMDKILAGLYNPGDGHIDPYSLTMALATGARKYGVLLKYPAPVTSLKPRP 219 +++ + + + + ++ P G + + A A +G + PV + Sbjct: 121 KQLTDRWAGVEVPDNYEAIFEPNSGVLFSENCIQAYRELAEAHGATVLTYTPVEDFEVTE 180 Query: 220 DGTWDVETPQGSVRANRIVNAAGFWAREVGKMIGLDHPLIPVQHQYVVTSTIPEVKALKR 279 D ++T +GS AN++V + G W ++ + ++ PL P + Q V E K Sbjct: 181 D-LVTIKTAKGSYTANKLVVSMGAWNSKLLSKLDVEIPLQPYR-QVVGFFECDEAK---- 234 Query: 280 ELPVLRDLEGSYYLRQERDGLLFG-PYESQEKMKLQASWVAHGVPPGFGKE---LFESDL 335 + ++ + +G+ +G P +K+ + P + D Sbjct: 235 ---YSNNAHYPAFMVEVENGIYYGFPSFGGSGLKIGYHSYGQQIDPDTINREFGAYPEDE 291 Query: 336 DRITEHVEAAMEMVP-VLKKADIINIVNGPITYSPDILPMVGPHQGVRNYWVAIGF-GYG 393 + + +E M LKK + T +PD ++ H N +A GF G+G Sbjct: 292 ANLRKFLEQYMPGANGELKKGAVCM-----YTKTPDEHFVIDLHPKYSNVAIAAGFSGHG 346 Query: 394 IIHAGGVGKYLSDWILHGEPPFDLIELDPNR 424 + VG+ L+ G+ D+ NR Sbjct: 347 FKFSSVVGETLAQLATTGKTEHDISIFSLNR 377 >1VRQ-A nrPDB Length = 964 Score = 329 bits (844), Expect = 2e-90, Method: Composition-based stats. Identities = 100/408 (24%), Positives = 184/408 (45%), Gaps = 33/408 (8%) Query: 463 RVSGLYK-ILESKCSMGFHAGWEQPHWFYKPGQDTQYRPSFRRTNWFRPVGSEYKQVMQR 521 R++ ++ L W++P W+Y ++ +R E K V Sbjct: 574 RLTAMHPWHLAHGAKFEDVGQWKRP-WYYPQDGESMDEAVYR----------ECKAVRDS 622 Query: 522 VGVIDLSPFGKFNIKGQDSTQLLDHLCAN--VIPKVGFTNISHMLTPRGRVYAELTVSHQ 579 VG++D S GK I+G+D+ + L+ + N KVG M G ++ + Sbjct: 623 VGMLDASTLGKIEIRGKDAAEFLNRMYTNGYTKLKVGMGRYGVMCKADGMIFDDGVTLRL 682 Query: 580 SPGEFLLITGSGSELHDLRWIEE--AAVRGGYDVEIRNITDELGVLGVAGPYARRVLQKL 637 + FL+ T +G L W+EE DV ++T++L + V GP +R V+ KL Sbjct: 683 AEDRFLMHTTTGGAADVLDWLEEWLQTEWPELDVTCTSVTEQLATVAVVGPRSRDVIAKL 742 Query: 638 TSE-DLSDDVFKFLQTKSLKI-SDIPVTAIRISYTGELGWELYHRREDSAALYERIMNAG 695 S D+S+D FKF+ + + + S I RIS++GEL +E+ ++E + AG Sbjct: 743 ASSLDVSNDAFKFMAFQDVTLDSGIEARISRISFSGELAFEIAIPAWHGLQVWEDVYAAG 802 Query: 696 QEEGIDNFGTYALNALRLEKAFRAWGSEMNCDTNPLEAGLDYFIKLNKPADFTGKQALKQ 755 QE I +GT ++ LR EK F G + + P +AG+++ + +K DF GK++ + Sbjct: 803 QEFNITPYGTETMHVLRAEKGFIIVGQDTDGTVTPQDAGMEWVV--SKLKDFVGKRSFSR 860 Query: 756 I-KAKGLKRRLVCLTLAT------DDVDPEGNESVWYKG--KVIGNTTSGSYSYSIQKSL 806 + ++ LV + + ++V +G + G T S ++ ++ Sbjct: 861 EDNVREDRKHLVSVLPVDSSLRLAEGAALVAADAVASEGVTPMEGWVTHAYNSPALGRTF 920 Query: 807 AFAYVPVELSEVGQQVEVELLGKNYPATIIQEPLVLTEPTRTRLQKDG 854 A + + +G+ ++ + G+ + LVL +P +R +DG Sbjct: 921 GLALIKNGRNRIGEVLKTPVDGQLVDVQVSD--LVLFDPEGSR--RDG 964 >3TFJ-A nrPDB Length = 369 Score = 329 bits (842), Expect = 4e-90, Method: Composition-based stats. Identities = 63/339 (18%), Positives = 147/339 (43%), Gaps = 15/339 (4%) Query: 508 FRPVGSEYKQVMQRVGVIDLSPFGKFNIKGQDSTQLLDHLCANVIPK--VGFTNISHMLT 565 F + YK + + V + D++ + I G+DS +L+ + + K +G ++ Sbjct: 41 FGSIEDSYKHLKEHVQIWDVAAERQVEISGKDSAELVQLMTCRDLSKSKIGRCYYCPIID 100 Query: 566 PRGRVYAELTVSHQSPGEFLLITGSGSELHDLRWIEEAAVRGGYDVEIRNITDELGVLGV 625 G + + V ++ + + + + G+ +++ + + ++ + Sbjct: 101 ENGNLVNDPVVLKLDENKWWISIADSDVIFFAK-----GLASGHKFDVKIVEPVVDIMAI 155 Query: 626 AGPYARRVLQKLTSEDLSDDVFKFLQTKSLKISDIPVTAIRISYTGELGWELYHRRED-S 684 GP + +++K+ + +++ KF R ++ + G+E+Y Sbjct: 156 QGPKSFALMEKVFGKKITE--LKFFGFDYFDFEGTKHLIARSGWSKQGGYEVYVENTQSG 213 Query: 685 AALYERIMNAGQEEGIDNFGTYALNAL-RLEKAFRAWGSEMNCDTNPLEAGLDYFIKLNK 743 LY+ + G+E + G N + R+E A ++G++ + + NP E G D ++ L+ Sbjct: 214 QKLYDHLFEVGKEFNV---GPGCPNLIERIESALLSYGNDFDNNDNPFECGFDQYVSLDS 270 Query: 744 PADFTGKQALKQIKAKGLKRRLVCLTLATDDVDPEGNESVW-YKGKVIGNTTSGSYSYSI 802 +F GK+ LK+IK KG +++L + + ++ G+++++ VIG S YS Sbjct: 271 DINFLGKEKLKEIKLKGPQKKLRGVKIDIKEISLTGSKNIYDENNNVIGELRSACYSPHF 330 Query: 803 QKSLAFAYVPVELSEVGQQVEVELLGKNYPATIIQEPLV 841 QK + A + E Q ++++ + P + Sbjct: 331 QKVIGIAMIKKSHWEASQGFKIQINDNTINGNVCDLPFI 369 >1NG3-A nrPDB Length = 390 Score = 302 bits (772), Expect = 6e-82, Method: Composition-based stats. Identities = 91/386 (23%), Positives = 153/386 (39%), Gaps = 51/386 (13%) Query: 59 YHLAKAGMRDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKIHYD----SIKLYERLEE 114 Y+LAK ++ L E + +T AAG+ H + +D S +LY+ L E Sbjct: 42 YYLAKEN-KNTALFESGTMGGRTTSAAAGMLGA-HAECEERDAFFDFAMHSQRLYKGLGE 99 Query: 115 ETGQVVGF----HQPGSIRLATTPERVDEFKY--QMTRTNWHATEQYIIEPEKIHELFPL 168 E + G H G +LA + E V + + + +W++ E++ E P Sbjct: 100 ELYALSGVDIRQHNGGMFKLAFSEEDVLQLRQMDDLDSVSWYS-------KEEVLEKEPY 152 Query: 169 LNMDKILAGLYNPGDGHIDPYSLTMALATGARKYGVLLKYPAPVTSLKPRPDGTWDVETP 228 + D I + D H++PY + A A+ G + PV ++ + + ++TP Sbjct: 153 ASGD-IFGASFIQDDVHVEPYFVCKAYVKAAKMLGAEIFEHTPVLHVERDGEALF-IKTP 210 Query: 229 QGSVRANRIVNAAGFWAREVGKMIGLDHPLIPVQHQY--VVTSTIPEVKALKRELPVLRD 286 G V AN +V A+G W+ K +GL++ +PV+ + V IP K L + Sbjct: 211 SGDVWANHVVVASGVWSGMFFKQLGLNNAFLPVKGECLSVWNDDIPLTKTLYHD------ 264 Query: 287 LEGSYYLRQERDGLLFGPYESQEKMKLQASWVAHGVPPGFGKELFESDLDRITEHVEAAM 346 Y+ + G L V + PG E DL + ++ A Sbjct: 265 ---HCYIVPRKSGRLV---------------VGATMKPGDWSE--TPDLGGLESVMKKAK 304 Query: 347 EMVPVLKKADIINIVNGPITYSPDILPMVGPHQG-VRNYWVAIGFGYGIIHAGGVGKYLS 405 M+P ++ + G + D P +G H R + A F GI+ A G +S Sbjct: 305 TMLPPIQNMKVDRFWAGLRPGTKDGKPYIGRHPEDSRILFAAGHFRNGILLAPATGALIS 364 Query: 406 DWILHGEPPFD-LIELDPNRYGKWTT 430 D I++ E D L +R Sbjct: 365 DLIMNKEVNQDWLHAFRIDRKEAVQI 390 >3SM8-A nrPDB Length = 381 Score = 292 bits (747), Expect = 5e-79, Method: Composition-based stats. Identities = 95/395 (24%), Positives = 159/395 (40%), Gaps = 56/395 (14%) Query: 43 AETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKIH 102 A+ ++IG G G S Y L+ G R VVL +++ ST +A T + ++ + Sbjct: 10 ADYLVIGAGIAGASTGYWLSAHG-RVVVLEREAQPGYHSTGRSAAHYTVAYGTPQVRALT 68 Query: 103 YDSIKLYERLEEETGQVVGFHQPGSIRLATTPERV-------DEFKYQMTRTNWHATEQY 155 S ++ GF + L+ PE V +E + Q + Sbjct: 69 AASRAFFDN------PPAGFCE--HPLLSPRPEMVVDFSDDPEELRRQYESGKALVPQMR 120 Query: 156 IIEPEKIHELFPLLNMDKILAGLYNPGDGHIDPYSLTMALATGARKY--GVLLKYPAPVT 213 +++ E+ + P+L DK+ Y+P ID +L G R+ VL + A Sbjct: 121 LLDAEQACSIVPVLRRDKVFGATYDPTGADIDTDALHQGYLRGIRRNQGQVLCNHEALEI 180 Query: 214 SLKPRPDGTWDVETPQGSVRANRIVNAAGFWAREVGKMIGLD-HPLIPVQHQYVVTSTIP 272 R DG W+V GS RA +VNAAG W + + G+ L P + + + P Sbjct: 181 ---RRVDGAWEVRCDAGSYRAAVLVNAAGAWCDAIAGLAGVRPLGLQPKRRSAFIFAPPP 237 Query: 273 EVKALKRELPVLRDLEGSYYLRQERDGLLFGPYESQEKMKLQASWVAHGVPPGFGKELFE 332 + + P+L L+ S+YL+ + G+L G + + ++ AH V P Sbjct: 238 GIDC--HDWPMLVSLDESFYLKPDA-GMLLGSPANADPVE------AHDVQP-------- 280 Query: 333 SDLDRITEHVEAAMEMVPVLKKADIINIVNGPITYSPDILPMVGPHQGVRNY-------- 384 E ++ A M ++++A + I T++ + V V Y Sbjct: 281 -------EQLDIATGMY-LIEEATTLTIRRPEHTWA-GLRSFVADGDLVAGYAANAEGFF 331 Query: 385 WVAIGFGYGIIHAGGVGKYLSDWILHGEPPFDLIE 419 WVA GYGI + +G+ + I H P L E Sbjct: 332 WVAAQGGYGIQTSAAMGEASAALIRHQPLPAHLRE 366 >4YSH-A nrPDB Length = 376 Score = 253 bits (645), Expect = 3e-67, Method: Composition-based stats. Identities = 101/398 (25%), Positives = 169/398 (42%), Gaps = 46/398 (11%) Query: 42 RAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAGLTTY---FHPGINL 98 R + I+GGG +G ++ + LAK R V + EK + +G++ AAG+ F L Sbjct: 4 RYDVAIVGGGVIGAAIGFELAKRRHR-VAIFEKGTMGSGASSAAAGMLGAQSEFSTSSPL 62 Query: 99 KKIHYDSIKL----YERLEEETGQVVGFHQPGSIRLATTPERVDEFKYQMTRTNWHATEQ 154 + S L E L E TG +G + G I+LATT E D+ T W + Sbjct: 63 VPLALQSRALMPALAEELRERTGIDIGLVEKGLIKLATTEEEADDLYRHYT--FWRGIGE 120 Query: 155 --YIIEPEKIHELFPLLNMDKILAGLYNPGDGHIDPYSLTMALATGARKYGVLLKYPAPV 212 + + E+ P L + + +Y PGDG + L ALA A G L V Sbjct: 121 PVQWLTKGEALEMEPRLA-EALAGAMYIPGDGQVSAPDLAAALAYAAASAGACLYEYTEV 179 Query: 213 TSLKPRPDGTWDVETPQGSVRANRIVNAAGFWAREVGKMIGLDHPLIPVQHQYVVTSTIP 272 ++ G ++T G+ A +V A+G WA +G +GL + PV+ + V+ Sbjct: 180 FDIRSDSSGHV-LDTTGGTFAAEAVVIASGAWAARLGARVGLSLSVYPVKGECVM----- 233 Query: 273 EVKALKRELPVLRDL----EGSYYLRQERDGLLFGPYESQEKMKLQASWVAHGVPPGFGK 328 ++ +P+L+ G Y + + + LL G A P F + Sbjct: 234 ----VRAPVPLLQTTVFAKNGCYIVPKSGNRLLIG---------------ATSTPGTFDR 274 Query: 329 ELFESDLDRITEHVEAAMEMVPVLKKADIINIVNGPITYSPDILPMVGPHQGVRNYWVAI 388 + + + + A +VP +++A+ + +G + D LP +G H R +VA Sbjct: 275 RVSAGGVMNL---LHRAAHLVPDIEQAEWVASWSGIRPQTEDGLPYLGEHPERRGLFVAA 331 Query: 389 G-FGYGIIHAGGVGKYLSDWILHGEPPFDLIELDPNRY 425 G + GI+ + G ++D + E FDL R+ Sbjct: 332 GHYRNGILLSPLTGLLVADLVERKETAFDLAPFSLTRH 369 >2UZZ-A nrPDB Length = 372 Score = 186 bits (472), Expect = 3e-47, Method: Composition-based stats. Identities = 59/389 (15%), Positives = 130/389 (33%), Gaps = 22/389 (5%) Query: 42 RAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAG--LTTYFHPGINLK 99 + + +IIG G VG + Y+ +AG+ ++ + H + + G Sbjct: 2 KYDLIIIGSGSVGAAAGYYATRAGLNVLMTDAHMPPHQHGSHHGDTRLIRHAYGEGEKYV 61 Query: 100 KIHYDSIKLYERLEEETGQVVGFHQPGSIRLATTPERVDEFKYQMTRTNWHATEQYIIEP 159 + + L++ L F + G I L ++ Sbjct: 62 PLVLRAQMLWDELSRHNEDDPIFVRSGVINLGPADSTFLANVAH--SAEQWQLNVEKLDA 119 Query: 160 EKIHELFPLLNMDKILAGLYNPGDGHIDPYSLTMALATGARKYGVLLKYPAPVTSLKPRP 219 + I +P + + GL+ G + A++ G + PVT+++ Sbjct: 120 QGIMARWPEIRVPDNYIGLFETDSGFLRSELAIKTWIQLAKEAGCAQLFNCPVTAIRHDD 179 Query: 220 DGTWDVETPQGSVRANRIVNAAGFWAREVGKMIGLDHPLIPVQHQYVVTSTIPEVKALKR 279 DG +ET G +A + + AG W +++ + P+ PV+ + + Sbjct: 180 DGVT-IETADGEYQAKKAIVCAGTWVKDLLP----ELPVQPVRKVFAWY---------QA 225 Query: 280 ELPVLRDLEGSYYLRQERDG-LLFGPYESQEKMKLQASWVAHGVPPGFGKELFESDLDRI 338 + + + + +G +G + +K+ + + F + Sbjct: 226 DGRYSVKNKFPAFTGELPNGDQYYGFPAENDALKIGKHNGGQVIHSADERVPFAEVVSDG 285 Query: 339 TEHVEAAMEMVPVLKKADIINIVNGPITYSPDILPMVGPHQGVRN-YWVAIGFGYGIIHA 397 +E ++P + + SPD ++ G N + G+G A Sbjct: 286 SEAFPFLRNVLPGI--GCCLYGAACTYDNSPDEDFIIDTLPGHDNTLLITGLSGHGFKFA 343 Query: 398 GGVGKYLSDWILHGEPPFDLIELDPNRYG 426 +G+ +D+ + FDL +R+ Sbjct: 344 SVLGEIAADFAQDKKSDFDLTPFRLSRFQ 372 >5X1I-A nrPDB Length = 474 Score = 109 bits (272), Expect = 6e-24, Method: Composition-based stats. Identities = 79/394 (20%), Positives = 139/394 (35%), Gaps = 87/394 (22%) Query: 508 FRPVGSEYKQVMQRVGVIDLSP-FGKFNIKGQDSTQLLDHLCANVIP--KVGFTNISHML 564 F +E + D + I+G+D+ +LL N + + Sbjct: 41 FSNWRTEQWAWRNSAVLFDQTHHMVDLYIRGKDALKLLSDTMINSPKGWEPNKAKQYVPV 100 Query: 565 TPRGRVYAELTVSHQSPGEFLLITGSGSELHDLRWIEEAAVRGGYDVEI--RNITDELGV 622 TP G V + + + + EF+ + W+ A GGY+V+I + + + Sbjct: 101 TPYGHVIGDGIIFYLAEEEFVYV----GRAPAANWLMYHAQTGGYNVDIVHDDRSPSRPM 156 Query: 623 ----------LGVAGPYARRVLQKLTSEDLSDDVFKFLQTKSLKISDIPVTAIRISYTGE 672 + GP A V++KL L + KF + I+ + + +R G Sbjct: 157 GKPVQRISWRFQIQGPKAWDVIEKLHGGTL--EKLKFFNMAEMNIAGMKIRTLRHGMAGA 214 Query: 673 LGWELYHRREDSAALYERIMNAGQEEGIDNFGTYALNALRLEKA---------------- 716 G E++ E I+ AG+E G+ G+ A + LE Sbjct: 215 PGLEIWGPYETQEKARNAILEAGKEFGLIPVGSRAYPSNTLESGWIPSPLPAIYTGDKLK 274 Query: 717 -FRAW-------------GSEMNCDT-----NPLEAGLDYFIKLNKPADFTGKQALKQIK 757 +R W GS ++ + NP E G F+K + DF G+ AL+ I Sbjct: 275 AYREWLPANSYEASGAIGGSFVSSNIEDYYVNPYEIGYGPFVKFDH--DFIGRDALEAI- 331 Query: 758 AKGLKRRLVCLTLATDDVDPEGNESVWYK---------------------------GKVI 790 +R+ V L DD+ + G V+ Sbjct: 332 DPATQRKKVTLAWNGDDMAKIYASLFDTEADAHYKFFDLPLANYANTNADAVLDAAGNVV 391 Query: 791 GNTTSGSYSYSIQKSLAFAYVPVELSEVGQQVEV 824 G + YSY+ +++L+ A + E+ VG ++ V Sbjct: 392 GMSMFTGYSYNEKRALSLATIDHEIP-VGTELTV 424 >5XAO-A nrPDB Length = 445 Score = 94.5 bits (233), Expect = 2e-19, Method: Composition-based stats. Identities = 66/382 (17%), Positives = 135/382 (35%), Gaps = 28/382 (7%) Query: 58 AYHLAKAGMR--DVVLLEKSELTAGSTWHA--AGLTTYFHPGINLKKIHYDSIKLYERLE 113 A HL ++G +V +L+ + + + A + ++ ++ +++ Sbjct: 24 ALHLVRSGYTPSNVTVLDAYPIPSSQSAGNDLAKIMGVSLRNPVDLQLALEARQMW---N 80 Query: 114 EETGQVVGFHQPGSIRLATTPERVDEFKYQMTR---TNWHATEQYIIEPEKIHELFPLLN 170 E+ FH G + A + + + K AT +++ ++I + PLL+ Sbjct: 81 EDELFKKFFHNTGRLDCAHGEKDIADLKSGYQALVDAGLDATNEWLDSEDEILKRMPLLS 140 Query: 171 MDKILA--GLYNPGDGHIDPYSLTMALATGARKYGVLL-KYPAPVTSLKPRPDGT-WDVE 226 D+I +++ G + A+ R GV Y A +G VE Sbjct: 141 RDQIKGWKAIFSKDGGWLAAAKAINAVGEYLRDQGVRFGFYGAGSFKAPLLAEGVCIGVE 200 Query: 227 TPQGS-VRANRIVNAAGFWAREVGKMIGLDHPLIPVQHQYVVTSTIPEVKALKRELPVLR 285 T G+ A+++V AAG W+ + + L + Y PE A + PV+ Sbjct: 201 TVDGTRYYADKVVLAAGAWSPTLVE---LHEQCVSKAWVYGHIQLTPEEAARYKNSPVVY 257 Query: 286 DLEGSYYLRQERDGLL-FGPYESQEKMKLQASWVAHGVPPGFG--KELFESDLDRITEHV 342 + + ++ G++ P + + D I + Sbjct: 258 NGDVGFFFEPNEHGVIKVCDEFPGFTRFKMHQPFGAKAPKRISVPRSHAKHPTDTIPDAS 317 Query: 343 E-----AAMEMVPVLKKADIINIVNGPITYSPDILPMVGPHQGVRNYWVAIG-FGYGIIH 396 + A +P K + N T + D ++ H +N+ +A G G+ Sbjct: 318 DVSIRRAIATFMPQFKNKKMFNQAMCWCTDTADAALLICEHPEWKNFVLATGDSGHSFKL 377 Query: 397 AGGVGKYLSDWILHGEPPFDLI 418 +GK++ + + G DL Sbjct: 378 LPNIGKHVVELLE-GTLADDLA 398 >3VQR-A nrPDB Length = 447 Score = 81.0 bits (198), Expect = 2e-15, Method: Composition-based stats. Identities = 66/403 (16%), Positives = 139/403 (34%), Gaps = 36/403 (8%) Query: 42 RAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKS-ELTAGSTWHAAGLTTYFHPGINLKK 100 R + V++G G VG++ AY+L V++++ +G + + F + Sbjct: 23 RFDYVVVGAGVVGLAAAYYLKVWSGGSVLVVDAGHAPGSGDSGRSMAAFRTFFSSTMNRL 82 Query: 101 IHYDSIKLYERLEEETGQVVGFHQPGSIRLATTPERVDEFKYQMTRTNWHATEQYIIEPE 160 + +++L+E + G+ +G + G + ER E + + + II PE Sbjct: 83 VAGSTVRLFED-AQRGGEDLGLVKSGYL-FVYDRERWREVEEPLREAGEEGRDYLIIPPE 140 Query: 161 KIH------------ELFPLLNMDKILAGLYNPGDGHIDPYSLTMALATGARKYGVLLKY 208 ++ E +L + + + G +D + A GV + Sbjct: 141 ELERRLGMNTRVSDGEEAEVLGVGDVEGAVLIRSAGFLDAEKVVDYYYRRASGAGVEFIF 200 Query: 209 PAPVTSLKPRPDGTWDVE---------TPQGSVRAN--------RIVNAAGFWAREVGKM 251 V ++ +P +E +V ++ ++V AAG W+ + Sbjct: 201 GRRVVGVELKPRVELGIEGEPLPWQEARASAAVLSDGTRVEVGEKLVVAAGVWSNRLLNP 260 Query: 252 IGLDHPLIPVQHQYV-VTSTIPEVKALKRELPVLRDLEGSYYLRQERDGLLFGPYESQEK 310 +G+D P + V+++ ++ + RE + + +L P + Sbjct: 261 LGIDTFSRPKKRMVFRVSASTEGLRRIMREGDLAGAGAPPLIILP--KRVLVRPAPREGS 318 Query: 311 MKLQASWVAHGVPPGFGKELFESDLDRITEHVEAAMEMVPVLKKADIINIVNGPITYSPD 370 +Q S G P ++ + + +P + A G S D Sbjct: 319 FWVQLSD-NLGRPFALEEDPQPEEHYYSLAILPILSLYLPQFQDAYPSGGWAGHYDISFD 377 Query: 371 ILPMVGPHQGVRNYWVAIGFGYGIIHAGGVGKYLSDWILHGEP 413 P+V A G GI+ + +G+ + L E Sbjct: 378 ANPVVFEPWESGIVVAAGTSGSGIMKSDSIGRVAAAVALGMES 420 >3PVC-A nrPDB Length = 689 Score = 55.6 bits (132), Expect = 8e-08, Method: Composition-based stats. Identities = 94/466 (20%), Positives = 148/466 (31%), Gaps = 92/466 (19%) Query: 18 QGRPSSAGLREGQESPPSPPEWKDRA-----ETVIIGGGCVGVSLAYHLAKAGMRDVVLL 72 Q R G Q P+ P + A + IIGGG V A L + G + Sbjct: 235 QKREMLTGTLPQQIHAPTAPWYHRPAATRCDDIAIIGGGIVSALTALALQRRGAVVTLYC 294 Query: 73 EKSELTAGSTWHAAGLTTYFHPGINLK------KIHYDSIKLYERLEEETGQVVGFHQPG 126 ++ G++ + G G N + + Y++L E+ G G Sbjct: 295 ADAQPAQGASGNRQGALYPLLNGKNDALETFFTSAFTFARRQYDQLLEQ-GIAFDHQWCG 353 Query: 127 SIRLATTPERVDEFKYQMTRTNWHATEQYIIEPEKIHELFPLLNMDKILAGLYNPGDGHI 186 +LA + +M T W + E++ EL +D G++ P G + Sbjct: 354 VSQLAFDDKS-RGKIEKMLHTQWPVEFAEAMSREQLSEL---AGLDCAHDGIHYPAGGWL 409 Query: 187 DPYSLTMALATGARKYGVLLKYPAPVTSLKPRPDGTWDVETPQGSVRANR---IVNAAGF 243 P LT AL A++ G+ Y + LK R D W + T S A ++ A G Sbjct: 410 CPSDLTHALMMLAQQNGMTCHYQHELQRLK-RIDSQWQL-TFGQSQAAKHHATVILATGH 467 Query: 244 ----WAREVGKMIGLDHPLIPVQHQYVVTSTIPEVKALKRELPVLRDLEGSYYLRQERDG 299 W + PL V+ Q T P + L++ L YL Sbjct: 468 RLPEWEQT------HHLPLSAVRGQVSHIPTTPVLSQLQQVLCY------DGYLTPV--- 512 Query: 300 LLFGPYESQEKMKLQASWVAHGVPPGFGKELFESDLDRITEHVEAAMEMVPVL---KKAD 356 Q + G F L E+ E + +P + ++ D Sbjct: 513 ----------NPANQHHCIGASYQRGDIATDFR--LTEQQENRERLLRCLPQVSWPQQVD 560 Query: 357 IIN--IVNGPITYSPDILPMVGPHQGVRN------------------------------- 383 + + G D LPMVG Sbjct: 561 VSDNQARCGVRCAIRDHLPMVGAVPDYAATLAQYQDLSRRIQHGGESEVNDIAVAPVWPE 620 Query: 384 YWVAIGFGY-GIIHAGGVGKYLSDWILHGEPPFD---LIELDPNRY 425 ++ G G G+ A V + L+ + P D L L+PNR+ Sbjct: 621 LFMVGGLGSRGLCSAPLVAEILAAQMFGEPLPLDAKTLAALNPNRF 666 >3PS9-A nrPDB Length = 676 Score = 55.6 bits (132), Expect = 8e-08, Method: Composition-based stats. Identities = 73/457 (15%), Positives = 131/457 (28%), Gaps = 70/457 (15%) Query: 11 GLALRSSQG----RPSSAGLREGQESPPSPPEWKDRA-----ETVIIGGGCVGVSLAYHL 61 G ++ +G R G+ E P W +R E IIGGG L+ L Sbjct: 232 GFTMQKRKGFGRKREMLCGVMEQTLPLPCSAPWFNRTGSSKREAAIIGGGIASALLSLAL 291 Query: 62 AKAGMRDVV-LLEKSELTAGSTWHAAGLTTYFHPGIN-----LKKIHYDSIKLYERLEEE 115 + G + + +++ S L + + Y++L + Sbjct: 292 LRRGWQVTLYCADEAPALGASGNRQGALYPLLSKHDEALNRFFSNAFTFARRFYDQLPVK 351 Query: 116 TGQVVGFHQPGSIRLATTPERVDEFKYQMTRTNWHATEQYIIEPEKIHELFPLLNMDKIL 175 G +L + + ++ + + + + + + Sbjct: 352 FDHDWC----GVTQLGWDEKSQHKIAQMLSMD----LPAELAVAVEANAVEQITGVATNC 403 Query: 176 AGLYNPGDGHIDPYSLTMALATGARKYGVLLKYPAPVTSLKPRPDGTWDVETPQGSVRAN 235 +G+ P G + P LT + A++ G+ + Y + + R D W + + Sbjct: 404 SGITYPQGGWLCPAELTRNVLELAQQQGLQIYYQYQLQNF-SRKDDCWLLNFAGDQQATH 462 Query: 236 RIVNAAGFWAREVGKMIGLDHPLIPVQHQYVVTSTIPEVKALKRELPVLRDLEGSYYLRQ 295 +V A P+ V Q T PE+ LK+ L YL Sbjct: 463 SVVVLANGHQISRFSQTS-TLPVYSVAGQVSHIPTTPELAELKQVLCY------DGYLTP 515 Query: 296 ERDGLLFGPYESQEKMKLQASWVAHGVP-PGFGKELFESDLDRITEHVEAAMEMVPVLKK 354 + P + + ++ L + A E+ K+ Sbjct: 516 Q------NPANQHHCIGASYHRGSEDTAYSEDDQQQNRQRLIDCFPQAQWAKEVDVSDKE 569 Query: 355 ADIINIVNGPITYSPDILPMVGPHQGVRNYWV------------------------AIGF 390 A G + D LPMVG V A Sbjct: 570 A-----RCGVRCATRDHLPMVGNVPDYEATLVEYASLAEQKDEAVSAPVFDDLFMFAALG 624 Query: 391 GYGIIHAGGVGKYLSDWILHGEPPFD---LIELDPNR 424 G+ A + L+ + P D L L+PNR Sbjct: 625 SRGLCSAPLCAEILAAQMSDEPIPMDASTLAALNPNR 661 >5EZ7-A nrPDB Length = 392 Score = 54.1 bits (128), Expect = 3e-07, Method: Composition-based stats. Identities = 43/263 (16%), Positives = 77/263 (29%), Gaps = 32/263 (12%) Query: 42 RAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKI 101 + +I+GGG G+ L L +AG V++ E + L G + + G+ + Sbjct: 7 STDILIVGGGIAGLWLNARLRRAGYATVLV-ESASLGGGQSVKSQGIIHGGAKYALHGAL 65 Query: 102 HYDSIKLYE---RLEEETGQVVGFHQPGSIRLA-----TTPERVDEFKYQMTRTNWHATE 153 S + + R G G L+ +P + + + Sbjct: 66 TGASEAIADMPRRWRACLGSDGELDLRGVRLLSEAHYLWSPGGLAGSLTSFFASKAVRSR 125 Query: 154 QYIIEPEKIHELFPLLNMDKILAGLYNPGDGHIDPYSLTMALATGARKYGVLLKYPAPVT 213 + E +L P L Y + D L A G L + Sbjct: 126 VEQAKGE---DLPPALRDKGFKGKAYRLTEIVFDVPDLI---RRLAELAGDSLLAGERIE 179 Query: 214 SLKPRPDGTWDVETPQGSVRANRIVNAAGFWAREVGKMIGLDHP---------------- 257 L + +RA R+V +AG + + +GL+ P Sbjct: 180 PL-REGRELAGLCVDGREIRAQRVVLSAGAGNEALLRELGLEQPAMQRRPLHMVMVKAAT 238 Query: 258 LIPVQHQYVVTSTIPEVKALKRE 280 L P+ + P + Sbjct: 239 LKPLYAHCLGAGPKPRITVTTHP 261 >5KOX-A nrPDB Length = 476 Score = 54.1 bits (128), Expect = 3e-07, Method: Composition-based stats. Identities = 47/262 (17%), Positives = 83/262 (31%), Gaps = 56/262 (21%) Query: 44 ETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKIHY 103 + +I GGG G+ LA L G+R VVL ++ S + +H Sbjct: 6 DVIIAGGGPTGLMLAGELRLHGVRTVVLEKEPTPNQHS---------------RSRGLHA 50 Query: 104 DSIKLYERLEEETGQVVGFHQPGSIR--LATTPERVDEFKYQMTRTNWHATEQYIIEPEK 161 SI++ + Q G + LA +F+ + P Sbjct: 51 RSIEVMD-------------QRGLLERFLAHGE----QFR---VGGFFAGLAAEW--PAD 88 Query: 162 IHELFPLLNMDKILAGLYNPGDGHIDPYSLTMALATGARKYGVLLKYPAPVTSLKPRPDG 221 + + L P + L L A + G ++ V L DG Sbjct: 89 LDTAHSYV--------LAIP---QVVTERL---LTEHATELGAEIRRGCEVAGLDQDADG 134 Query: 222 TWDVETPQGSVRANRIVNAAGFWAREVGKMIGLDHPLIPVQHQYVVTS--TIPEVKALKR 279 +RA +V G V +++G+D P P + + ++ V+ L Sbjct: 135 VTAELADGTRLRARYLVGCDGG-RSTVRRLLGVDFPGEPTRVETLLADVRIDVPVETLTA 193 Query: 280 ELPVLRDLEGSYYLRQERDGLL 301 + +R + + DG Sbjct: 194 VVAEVRKTQLRFGAVPAGDGFF 215 >3ATQ-A nrPDB Length = 453 Score = 52.1 bits (123), Expect = 1e-06, Method: Composition-based stats. Identities = 67/407 (16%), Positives = 124/407 (30%), Gaps = 82/407 (20%) Query: 42 RAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKI 101 + + +IIGGG G S AY L++ G++ +++ K G + K Sbjct: 6 KYDVLIIGGGFAGSSAAYQLSRRGLKILLVDSKPW----------NRIGDKPCGDAVSKA 55 Query: 102 HYDSIKLYERLEEETGQVVGFHQPGSIRLATTPERVDEFKYQMTRTNWHATEQYIIEPEK 161 H+D + + EE + I+L +P+ + + E Sbjct: 56 HFDKLGMPYPKGEELENKI-----NGIKL-YSPDM---------------QTVWTVNGEG 94 Query: 162 IHELFPLLNMDKILAGLYNPGDGHIDPYSLTMALATGARKYGVLLKYPAPV-----TSLK 216 PL N + A+ GV + Sbjct: 95 FELNAPLYN----------------------QRVLKEAQDRGVEIWDLTTAMKPIFEDGY 132 Query: 217 PRPDGTWDVETPQGSVRANRIVNAAGFWAREVGKMIGLDHPLIPVQHQYVVTSTIPEVKA 276 + ++ T + +++V A ++R + + P+ T + + A Sbjct: 133 VKGAVLFNRRTNEELTVYSKVVVEATGYSRSFRSKLPPELPI---------TEDLDDKDA 183 Query: 277 LKRELPVL---RDLEGSYYLRQERDGLLF-GPYESQEKMKLQASWVAHGVPPGFG----K 328 VL D+E YLR D G Y V G+ G G Sbjct: 184 DVAYREVLLTKEDIEDHDYLRIFIDQETSPGGYWWYFPKGKNKVNVGLGIQGGMGYPSIH 243 Query: 329 ELFESDLDRITEHVEAAMEMVPVLKKADIINIVNGPITYSPDILPMVGPHQGVRNYWVAI 388 E ++ LD+ V+ + +V K ++ T + + + ++G N Sbjct: 244 EYYKKYLDKYAPDVDKSKLLV---KGGALVPTRRPLYTMAWNGIIVIGDSGFTVNPVHGG 300 Query: 389 GFGYGIIHAGGVGKYLSDWILHGEPPF----DLIELDPNRYGKWTTT 431 G G +I K + G+ D+ N YG + Sbjct: 301 GKGSAMISGYCAAKAILSAFETGDFSASGLWDMNICYVNEYGAKQAS 347 >1QO8-A nrPDB Length = 566 Score = 51.0 bits (120), Expect = 2e-06, Method: Composition-based stats. Identities = 32/214 (14%), Positives = 71/214 (33%), Gaps = 26/214 (12%) Query: 39 WKDRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAGLTTYFHPGINL 98 + + +++G G G + + KAG +V+L++K+ + G++ +AG Sbjct: 118 PSETTQVLVVGAGSAGFNASLAAKKAGA-NVILVDKAPFSGGNSMISAGGMNAVGTKQQT 176 Query: 99 KKIHYDSIKLYERLEEETGQVVGFHQPGSIRLATTP-ERVDEFKYQMTRTNWHATEQYII 157 D ++ + + G Q I+L T E+ + + + + Sbjct: 177 AHGVEDKVEWFIE-----DAMKGGRQQNDIKLVTILAEQSADGVQWLESLGANLDDLKRS 231 Query: 158 EPEKIHELFPLLNMDKILAGLYNPGDGHIDPYSLTMALATGARKYGVLLKYPAPVTSLKP 217 ++ + P G + L A++ G+ + + V L Sbjct: 232 GGARVDR-------------THRPHGGKSSGPEIIDTLRKAAKEQGIDTRLNSRVVKLVV 278 Query: 218 RPDGTW------DVETPQGSVRANRIVNAAGFWA 245 D + T + A +V A G + Sbjct: 279 NDDHSVVGAVVHGKHTGYYMIGAKSVVLATGGYG 312 >3CUK-A nrPDB Length = 347 Score = 50.2 bits (118), Expect = 3e-06, Method: Composition-based stats. Identities = 64/393 (16%), Positives = 114/393 (29%), Gaps = 68/393 (17%) Query: 45 TVIIGGGCVGVSLA------YHLAKAGMRDVVLLEKSELTAGSTWHAAGLTTYFHPGINL 98 V+IG G +G+S A YH + V ++ +T AAGL + N Sbjct: 3 VVVIGAGVIGLSTALCIHERYHSVLQPLDIKVYADRFTPLT-TTDVAAGLWQPYLSDPNN 61 Query: 99 KKIHYDSIKLYERLEEETGQVVGFHQPGSIRLATTPERVDEFKYQMTRTNWH--ATEQYI 156 + S + ++ L G ++ + F + +W Sbjct: 62 PQEADWSQQTFDYLLSHVHSPNA-ENLGLFLIS----GYNLFHEAIPDPSWKDTVLGFRK 116 Query: 157 IEPEKIHELFPLLNMDKILAGLYNPGDGHIDPYSLTMALATGARKYGVLLKYPAPVTSLK 216 + P ++ ++FP + ++ + L + GV + + Sbjct: 117 LTPREL-DMFP------DYGYGWFHTSLILEGKNYLQWLTERLTERGVKFFQRKVESFEE 169 Query: 217 PRPDGTWDVETPQGSVRANRIVNAAGFWAREVGKMIGLDHPLIPVQHQYVVTSTIPEVKA 276 +G A+ IVN G WA + + D L P + Q ++ P +K Sbjct: 170 VAREG------------ADVIVNCTGVWAGALQR----DPLLQPGRGQ-IMKVDAPWMK- 211 Query: 277 LKRELPVLRDLEGSYYLRQERDGLLFGPYESQEKMKLQASWVAHGVPPGFGKELFESDLD 336 + L + + ++ Q + G EL Sbjct: 212 -------------HFILTHDPERGIYNSPYIIPG--TQTVTLGGIFQLGNWSELNNIQDH 256 Query: 337 RITEHVEAAMEMVPVLKKADII---NIVNGPITYSPDILPMVGPHQ---------GVRNY 384 E + P LK A II + G Y Sbjct: 257 NTI--WEGCCRLEPTLKNARIIGERTGFRPVRPQIRLEREQLRTGPSNTEVIHNYGHGGY 314 Query: 385 WVAIGFGYGIIHAGGVGKYLSDWILHGEPPFDL 417 + I +G + A G+ L + L PP L Sbjct: 315 GLTIHWGCALEAAKLFGRILEEKKLSRMPPSHL 347 >2RGO-A nrPDB Length = 607 Score = 49.8 bits (117), Expect = 5e-06, Method: Composition-based stats. Identities = 49/331 (14%), Positives = 95/331 (28%), Gaps = 53/331 (16%) Query: 65 GMRDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKIHYDSIKLYERLEEET---GQVVG 121 G++ ++ E + G++ + L H GI K +D + + + E G Sbjct: 41 GIKTGLI-EMQDFAEGTSSRSTKLV---HGGIRYLK-TFDVEVVADTVGERAVVQGIAPH 95 Query: 122 FHQPGSIRLATTPERVD------------EFKYQMTRTNWHATEQYIIEPEKIHELFPLL 169 +P + L + + ++ E Y + PE++ E P L Sbjct: 96 IPKPDPMLLPIYEDEGATTFNMFSVKVAMDLYDKLANVTGTKYENYTLTPEEVLEREPFL 155 Query: 170 NMDKILAG----LYNPGDGHIDPYSLTMALATGARKYGVLLKYPAPVTSLKPRPDGTWDV 225 + + + D + ++ A + G L D V Sbjct: 156 KKEGLKGAGVYLDFRNNDARLVIDNI-----KKAAEDGAYLVSKMKAVGFLYEGDQIVGV 210 Query: 226 ETPQG------SVRANRIVNAAGFWAREVGKMIGLDHPLIPVQHQYVVTSTIPEVKALKR 279 + ++A ++N +G W +V + + P+ P + + K L Sbjct: 211 KARDLLTDEVIEIKAKLVINTSGPWVDKV-RNLNFTRPVSPKMRPTKGIHLVVDAKKLPV 269 Query: 280 ELPVLRDLEGS----YYLRQERDGLLFGPYESQEKMKLQASWVAHGVPPGFGKELFESDL 335 P D + + FG + P +E + L Sbjct: 270 PQPTYFDTGKQDGRMVFAIPRENKTYFGT--------TDTDYQGDFTDPKVTQEDVDYLL 321 Query: 336 DRITEHVEAAMEMVPVLKKADIINIVNGPIT 366 D I A + ADI G Sbjct: 322 DVINHRYPEAN-----ITLADIEASWAGLRP 347 >2RGH-A nrPDB Length = 571 Score = 49.8 bits (117), Expect = 6e-06, Method: Composition-based stats. Identities = 49/331 (14%), Positives = 95/331 (28%), Gaps = 53/331 (16%) Query: 65 GMRDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKIHYDSIKLYERLEEET---GQVVG 121 G++ ++ E + G++ + L H GI K +D + + + E G Sbjct: 55 GIKTGLI-EMQDFAEGTSSRSTKLV---HGGIRYLK-TFDVEVVADTVGERAVVQGIAPH 109 Query: 122 FHQPGSIRLATTPERVD------------EFKYQMTRTNWHATEQYIIEPEKIHELFPLL 169 +P + L + + ++ E Y + PE++ E P L Sbjct: 110 IPKPDPMLLPIYEDEGATTFNMFSVKVAMDLYDKLANVTGTKYENYTLTPEEVLEREPFL 169 Query: 170 NMDKILAG----LYNPGDGHIDPYSLTMALATGARKYGVLLKYPAPVTSLKPRPDGTWDV 225 + + + D + ++ A + G L D V Sbjct: 170 KKEGLKGAGVYLDFRNNDARLVIDNI-----KKAAEDGAYLVSKMKAVGFLYEGDQIVGV 224 Query: 226 ETPQG------SVRANRIVNAAGFWAREVGKMIGLDHPLIPVQHQYVVTSTIPEVKALKR 279 + ++A ++N +G W +V + + P+ P + + K L Sbjct: 225 KARDLLTDEVIEIKAKLVINTSGPWVDKV-RNLNFTRPVSPKMRPTKGIHLVVDAKKLPV 283 Query: 280 ELPVLRDLEGS----YYLRQERDGLLFGPYESQEKMKLQASWVAHGVPPGFGKELFESDL 335 P D + + FG + P +E + L Sbjct: 284 PQPTYFDTGKQDGRMVFAIPRENKTYFGT--------TDTDYQGDFTDPKVTQEDVDYLL 335 Query: 336 DRITEHVEAAMEMVPVLKKADIINIVNGPIT 366 D I A + ADI G Sbjct: 336 DVINHRYPEAN-----ITLADIEASWAGLRP 361 >1KNR-A nrPDB Length = 540 Score = 49.4 bits (116), Expect = 7e-06, Method: Composition-based stats. Identities = 80/551 (14%), Positives = 151/551 (27%), Gaps = 115/551 (20%) Query: 39 WKDRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAGLTTYFHPGINL 98 + + +IIG G G+SLA LA V++L K +T GST F+ + Sbjct: 5 PEHSCDVLIIGSGAAGLSLALRLADQ--HQVIVLSKGPVTEGST---------FYAQGGI 53 Query: 99 KKIHYDSIKLYERLEEETGQVVGFHQPGSIRLATTPERVDEFKYQMTRTNWHATEQYIIE 158 + ++ + +E+ G ++ +N + Q++I+ Sbjct: 54 AAVFDETDSIDSHVEDTLIAGAGICDRHAVEFV--------------ASNARSCVQWLID 99 Query: 159 PEKIHELFPLLNMDKILAGLYNPGDGHIDPYSLTMALATGARKYGVLLKYPAPVTSLKPR 218 + + N ++ G H A V P + R Sbjct: 100 QGVLFDTHIQPNGEESYHLTREGGHSHRRILHAADATGREVETTLVSKALNHPNIRVLER 159 Query: 219 PDGTWDVETPQGSVRANRIVNAAGFWA------------REVGKMIGLDHPLI----P-- 260 + + + + + R V A W V G P Sbjct: 160 TNAVDLIVSDKIGLPGTRRVVGAWVWNRNKETVETCHAKAVVLATGGASKVYQYTTNPDI 219 Query: 261 ----------------VQHQYVVTSTIPEVKALKRELPVLRDLEGSYYLRQERDGLLFGP 304 ++ R + L G + DG F P Sbjct: 220 SSGDGIAMAWRAGCRVANLEFNQFHPTALYHPQARNFLLTEALRGEGAYLKRPDGTRFMP 279 Query: 305 YESQEKMKLQASWVAHGV-------------------PPGFGKELFESDLDRITEH-VEA 344 + VA + P F ++ F +++ ++ Sbjct: 280 DFDERGELAPRDIVARAIDHEMKRLGADCMFLDISHKPADFIRQHFPMIYEKLLGLGIDL 339 Query: 345 AMEMVPVLKKADIINIVNGPITYSPDILPMVGPH--QGVRNYWVAIGFGYGIIHAGGVGK 402 E VP++ A Y+ + MV H V + Y +H Sbjct: 340 TQEPVPIVPAAH----------YTCGGV-MVDDHGRTDVEGLYAIGEVSYTGLHG----- 383 Query: 403 YLSDWILHGEPPFDLIELDPNRYGKWTTTQYTEAKARESYGFNNIVGYPKEERFAGRPTQ 462 ++ + L+E YG W+ + + R Y + P +E P + Sbjct: 384 --ANLMASN----SLLECLV--YG-WSAAE--DITRRMPYAHDISTLPPWDESRVENPDE 432 Query: 463 RVSGLYKILESKCSMGFHAGWEQPHWFYKPGQDTQYRPSFRRTNWFRPVGSEYKQVMQRV 522 RV + E + M + G + R R T + + Y Sbjct: 433 RVVIQHNWHELRLFMWDYVGIVR-------TTKRLERALRRITMLQQEIDEYYAHFRVSN 485 Query: 523 GVIDLSPFGKF 533 +++L + Sbjct: 486 NLLELRNLVQV 496 >1VE9-A nrPDB Length = 347 Score = 47.1 bits (110), Expect = 4e-05, Method: Composition-based stats. Identities = 72/394 (18%), Positives = 120/394 (30%), Gaps = 70/394 (17%) Query: 45 TVIIGGGCVGVSLA------YHLAKAGMRDVVLLEKSELTAGSTWHAAGLTTYFHPGINL 98 V+IG G +G+S A YH + V ++ +T AAGL + + Sbjct: 3 VVVIGAGVIGLSTALCIHERYHSVLQPLDVKVYADRFTP-FTTTDVAAGLWQPYTSEPSN 61 Query: 99 KKIHYDSIKLYERLEEETGQVVGFHQPGSIRLATTPERVDEFKYQMTRTNWH---ATEQY 155 + + + + L G P + + TP + + Sbjct: 62 PQEANWNQQTFNYLLSHIG------SPNAANMGLTPVSGYNLFREAVPDPYWKDMVLGFR 115 Query: 156 IIEPEKIHELFPLLNMDKILAGLYNPGDGHIDPYSLTMALATGARKYGVLLKYPAPVTSL 215 + P ++ ++FP D + ++ L + GV V S Sbjct: 116 KLTPREL-DMFP----DYRYG--WFNTSLILEGRKYLQWLTERLTERGVKFFLR-KVESF 167 Query: 216 KPRPDGTWDVETPQGSVRANRIVNAAGFWAREVGKMIGLDHPLIPVQHQYVVTSTIPEVK 275 + E +G A+ I+N G WA + D L P + Q ++ P +K Sbjct: 168 E---------EVARGG--ADVIINCTGVWAGVLQP----DPLLQPGRGQ-IIKVDAPWLK 211 Query: 276 ALKRELPVLRDLEGSYYLRQERDGLLFGPYESQEKMKLQASWVAHGVPPGFGKELFESDL 335 + R + S Y+ LQA + G E+ Sbjct: 212 NFIITHDLERGIYNSPYIIP----------------GLQAVTLGGTFQVGNWNEINNIQD 255 Query: 336 DRITEHVEAAMEMVPVLKKADIINIVNGPITYSPDIL------------PMVGPHQGVRN 383 E + P LK A I+ G P + V + G Sbjct: 256 HNTI--WEGCCRLEPTLKDAKIVGEYTGFRPVRPQVRLEREQLRFGSSNTEVIHNYGHGG 313 Query: 384 YWVAIGFGYGIIHAGGVGKYLSDWILHGEPPFDL 417 Y + I +G + A GK L + L PP L Sbjct: 314 YGLTIHWGCALEVAKLFGKVLEERNLLTMPPSHL 347 >1RP0-A nrPDB Length = 284 Score = 46.7 bits (109), Expect = 5e-05, Method: Composition-based stats. Identities = 21/95 (22%), Positives = 35/95 (36%), Gaps = 6/95 (6%) Query: 44 ETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKIHY 103 + V++G G G+S AY ++K V ++E+S G W G + Sbjct: 41 DVVVVGAGSAGLSAAYEISKNPNVQVAIIEQSVSPGGGAW-LGGQLFSAMIVRKPAHLFL 99 Query: 104 DSIKLYERLEEETG----QVVGFHQPGSIRLATTP 134 D I + E++T F +L P Sbjct: 100 DEIGVAYD-EQDTYVVVKHAALFTSTIMSKLLARP 133 >3DA1-A nrPDB Length = 561 Score = 46.3 bits (108), Expect = 6e-05, Method: Composition-based stats. Identities = 56/349 (16%), Positives = 110/349 (31%), Gaps = 45/349 (12%) Query: 40 KDRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWH-----AAGLTTYFHP 94 + + + ++IGGG G +A G++ L+E ++ +G++ GL Sbjct: 16 EKQLDLLVIGGGITGAGIALDAQVRGIQ-TGLVEMNDFASGTSSRSTKLVHGGLRYLKQF 74 Query: 95 GINLKKIHYDSIKLYER-----LEEETGQVVGFHQPGSIRLATTPERVDEFKYQMTRTNW 149 I L + E + F + +T+ Y Sbjct: 75 EIKLVAEVGKERAIVYENAPHVTTPEWMLLPIFKDGTFGKFSTSLGLK---VYDYLADVR 131 Query: 150 HATEQYIIEPEKIHELFPLLNMDKIL-AGLYNPGDGHIDPYSLTMALATGARKYGVLLKY 208 +Y++ ++ E PLL + + G+Y + D LT+ + A G + Sbjct: 132 KDERRYMLNEKQTLEKEPLLRKENLKGGGIYV--EYRTDDARLTLEIMKEAVARGAVALN 189 Query: 209 PAPVTSLKPRPDGTWDV-------ETPQGSVRANRIVNAAGFWAREVGKMIGLDHPLIPV 261 V S V +T ++ A ++VNAAG W + + Sbjct: 190 YMKVESFIYDQGKVVGVVAKDRLTDTTH-TIYAKKVVNAAGPWVDTLREKD------RSK 242 Query: 262 QHQYVVTSTIPEVKALKRELPVLRDLEGSYYLRQERDGLLFGPYESQEKMKLQASWVAHG 321 +Y+ V + + L + Y E DG + + + Sbjct: 243 HGKYLK--LSKGVHLVVDQSRF--PLRQAVYFDTESDGRMI------FAIPREGKTYIGT 292 Query: 322 VPPGFGKELFESDLDRITEH--VEAAMEMVPVLKKA--DIINIVNGPIT 366 + K++ + + AA M P L+ D+ + G Sbjct: 293 TDTFYDKDIASPRMTVEDRDYILAAANYMFPSLRLTADDVESSWAGLRP 341 >5NCC-A nrPDB Length = 594 Score = 46.0 bits (107), Expect = 7e-05, Method: Composition-based stats. Identities = 33/209 (15%), Positives = 63/209 (30%), Gaps = 18/209 (8%) Query: 32 SPPSPPEWKDRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAGLTTY 91 S S P + + +++GGG LA L+ G + V++LE T Sbjct: 13 SDSSSPVAGQKYDYILVGGGTAACVLANRLSADGSKRVLVLEAGPDNTSRDVKIPAAITR 72 Query: 92 FHPGINLKKIHYDSIKLYERLEEETGQVVGFHQPGSIRLATTPERVDEFKY-QMTRTNWH 150 L+ L+E+ + + G + ++ + + Sbjct: 73 LFRSP-------LDWNLFSELQEQLAERQIYMARGRLLGGSSATNATLYHRGAAGDYDAW 125 Query: 151 ATEQYIIEPEKIHELFPLLNMDKILA-GLYNPGDGHIDPYS-------LTMALATGARKY 202 E + E + F + G Y+ G + + L A A + Sbjct: 126 GVEGW--SSEDVLSWFVQAETNADFGPGAYHGSGGPMRVENPRYTNKQLHTAFFKAAEEV 183 Query: 203 GVLLKYPAPVTSLKPRPDGTWDVETPQGS 231 G+ S GT+ V +G+ Sbjct: 184 GLTPNSDFNDWSHDHAGYGTFQVMQDKGT 212 >3ISH-A nrPDB Length = 311 Score = 44.4 bits (103), Expect = 2e-04, Method: Composition-based stats. Identities = 16/68 (23%), Positives = 30/68 (44%), Gaps = 3/68 (4%) Query: 44 ETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKIHY 103 + IIGGG G+S + + G+++ VL EK T + +PG+ Sbjct: 3 DCAIIGGGPAGLSAGLYATRGGVKNAVLFEKGMPGGQITGSSE---IENYPGVKEVVSGL 59 Query: 104 DSIKLYER 111 D ++ ++ Sbjct: 60 DFMQPWQE 67 >3R9U-A nrPDB Length = 315 Score = 44.0 bits (102), Expect = 3e-04, Method: Composition-based stats. Identities = 13/42 (30%), Positives = 22/42 (52%) Query: 44 ETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHA 85 + IIGGG G+S + + G+++VV+ EK T + Sbjct: 6 DVAIIGGGPAGLSAGLYATRGGLKNVVMFEKGMPGGQITSSS 47 >1D4E-A nrPDB Length = 572 Score = 44.0 bits (102), Expect = 3e-04, Method: Composition-based stats. Identities = 39/212 (18%), Positives = 69/212 (32%), Gaps = 24/212 (11%) Query: 40 KDRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAGLTTYFHPGINLK 99 K+ + VIIG G G++ A AG + V+LLEK + G+T AAG K Sbjct: 124 KETTDVVIIGSGGAGLAAAVSARDAGAK-VILLEKEPIPGGNTKLAAGGMNAAETKPQAK 182 Query: 100 KIHYDSIKLYERLEEETGQVVGFHQPGSIRLATTPERVDEFKYQMTRTNWHATEQYIIEP 159 +E++ ++ G + E + + + + + Sbjct: 183 ----------LGIEDKKQIMIDDTMKGGRNI-----NDPELVKVLANNSSDSID--WLTS 225 Query: 160 EKIHELFPLLNMDKILAGLYNPGDGHIDPYSLTMALATGARKYGVLLKYPAPVTSLKPRP 219 + + P G + L A K G ++ + V + Sbjct: 226 MGADMTDVGRMGGASVNRSHRPTGGAGVGAHVAQVLWDNAVKRGTDIRLNSRVVRILEDA 285 Query: 220 DGTWDVETPQGSVR------ANRIVNAAGFWA 245 G +G A+ +V AAG +A Sbjct: 286 SGKVTGVLVKGEYTGYYVIKADAVVIAAGGFA 317 >4DGK-A nrPDB Length = 501 Score = 43.3 bits (100), Expect = 5e-04, Method: Composition-based stats. Identities = 46/281 (16%), Positives = 94/281 (33%), Gaps = 44/281 (15%) Query: 45 TVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAG-------STWHAAGLTTYFHPGIN 97 T +IG G G++LA L AG+ ++L ++ + AG T P Sbjct: 4 TTVIGAGFGGLALAIRLQAAGIPVLLLEQRDKPGGRAYVYEDQGFTFDAGPTVITDPSAI 63 Query: 98 LKKIHYDSIKL-----------YERLEEETGQVVGFHQPGSIRLA----TTPERVDEFKY 142 + +L + RL E+G+V + + A P V+ ++ Sbjct: 64 EELFALAGKQLKEYVELLPVTPFYRLCWESGKVFNYDNDQTRLEAQIQQFNPRDVEGYRQ 123 Query: 143 QMTRTNWHATEQYI-------IEPEKIHELFPLLNMDKILAGLYNPGDGHIDPYSLTMAL 195 + + E Y+ + + P L + +Y+ +I+ L A Sbjct: 124 FLDYSRAVFKEGYLKLGTVPFLSFRDMLRAAPQLAKLQAWRSVYSKVASYIEDEHLRQAF 183 Query: 196 ATGARKYGVLLKYPAPVTSLKPRPDGTWDVETPQGSVRANRIVNAAGFWAREVGKMIGLD 255 + + G + + +L + W V P+G V MI L Sbjct: 184 SFHSLLVGGNPFATSSIYTLIHALEREWGVWFPRG------------GTGALVQGMIKL- 230 Query: 256 HPLIPVQHQYVVTSTIPEVKALKRELPVLRDLEGSYYLRQE 296 + + V+ + + ++ ++ + +G +L Q Sbjct: 231 --FQDLGGEVVLNARVSHMETTGNKIEAVHLEDGRRFLTQA 269 >5KXJ-A nrPDB Length = 557 Score = 42.5 bits (98), Expect = 7e-04, Method: Composition-based stats. Identities = 34/208 (16%), Positives = 66/208 (31%), Gaps = 25/208 (12%) Query: 39 WKDRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAGLTTYFHPGINL 98 + + +IIG G G+SLA LA+ V++L K ++ GST F+ + Sbjct: 5 PELSCDVLIIGSGAAGLSLALRLAEK--HKVIVLSKGPVSEGST---------FYAQGGI 53 Query: 99 KKIHYDSIKLYERLEEETGQVVGFHQPGSIRLATTPERVDEFKYQMTRTNWHATEQYIIE 158 + ++ + +E+ G ++ +N Q++I+ Sbjct: 54 AAVFDETDSIASHVEDTLIAGAGICDRHAVEFV--------------ASNARTCVQWLID 99 Query: 159 PEKIHELFPLLNMDKILAGLYNPGDGHIDPYSLTMALATGARKYGVLLKYPAPVTSLKPR 218 + + N + G H A V P + R Sbjct: 100 QGVLFDTHVQPNGKESYHLTREGGHSHRRILHAADATGKEVETTLVSRAQNHPNIQVLER 159 Query: 219 PDGTWDVETPQGSVRANRIVNAAGFWAR 246 + + + + + R V A W R Sbjct: 160 SNAVDLIISDKMGLPGPRRVVGAWIWNR 187 >6BRD-A nrPDB Length = 476 Score = 42.1 bits (97), Expect = 0.001, Method: Composition-based stats. Identities = 49/231 (21%), Positives = 79/231 (34%), Gaps = 58/231 (25%) Query: 43 AETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKIH 102 + +++GGG G+ LA L G+R +VL +++E T S + + Sbjct: 2 FDVIVVGGGPTGLMLAGELRLHGVRVLVLEKETEPTRQSRAQGLHVRSIE---------V 52 Query: 103 YDSIKLYERLEEETGQVV--GFHQPGSIRLATT-PERVDEFKYQMTRTNWHATEQYIIEP 159 L ER E V GF LAT+ PER+D + P Sbjct: 53 MAQRGLLERFLERGHTVAVGGFFAG----LATSWPERLDTAHSYVLAV-----------P 97 Query: 160 EKIHELFPLLNMDKILAGLYNPGDGHIDPYSLTMALATGARKYGVLLKYPAPVTSLKPRP 219 + I E LA A G ++ + L+ Sbjct: 98 QVITE----------------------------QLLAEHATALGAEIRRGRALVGLRQDE 129 Query: 220 DGTWDVETPQGS-VRANRIVNAAGFWAREVGKMIGLDHPLIPVQHQYVVTS 269 DG V+ G +RA +V G V K++G+ P P + + ++ Sbjct: 130 DGVT-VDLADGEQLRARYVVGCDGG-RSTVRKLLGVAFPGEPSRVETLLGE 178 >4C5O-A nrPDB Length = 357 Score = 42.1 bits (97), Expect = 0.001, Method: Composition-based stats. Identities = 19/87 (21%), Positives = 32/87 (36%), Gaps = 2/87 (2%) Query: 41 DRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKK 100 D + V+IGGG G+S Y L ++G+ V+L ++ L + G + Sbjct: 2 DSVDVVVIGGGQSGLSAGYFLRRSGLSYVILDAEASPGGAWQHAWHSLHLFSPAGWSSIP 61 Query: 101 IH--YDSIKLYERLEEETGQVVGFHQP 125 S Y E + + Q Sbjct: 62 GWPMPASQGPYPARAEVLAYLAQYEQK 88 >4REP-A nrPDB Length = 495 Score = 42.1 bits (97), Expect = 0.001, Method: Composition-based stats. Identities = 17/65 (26%), Positives = 31/65 (47%), Gaps = 3/65 (4%) Query: 177 GLYNPGDGHIDPYSLTMALATGARKYGVLLKYPAPVTSLKPRPDGTWDVETPQGSVRANR 236 G Y P G + ++ +L A+K GV ++ VT++ + VET GS ++ Sbjct: 215 GTYYPDGGM---HRISQSLFELAQKVGVKFRFRESVTNITTSKNKVTGVETKNGSYLSDL 271 Query: 237 IVNAA 241 +V+ Sbjct: 272 VVSNM 276 >3FPZ-A nrPDB Length = 326 Score = 41.7 bits (96), Expect = 0.001, Method: Composition-based stats. Identities = 22/99 (22%), Positives = 41/99 (41%), Gaps = 6/99 (6%) Query: 43 AETVIIGGGCVGVSLAYHLAKAGMR-DVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKI 101 ++ +I+G G G+S AY +AK V ++E S G +W L F + K Sbjct: 66 SDVIIVGAGSSGLSAAYVIAKNRPDLKVCIIESSVAPGGGSWLGGQL---FSAMVMRKPA 122 Query: 102 HYDSIKLYERLEEETGQVVGFHQPGSIRLATTPERVDEF 140 H +L + E + ++ ++T +V + Sbjct: 123 HLFLQEL--EIPYEDEGDYVVVKHAALFISTVLSKVLQL 159 >1C0L-A nrPDB Length = 363 Score = 41.3 bits (95), Expect = 0.002, Method: Composition-based stats. Identities = 53/265 (20%), Positives = 85/265 (32%), Gaps = 45/265 (16%) Query: 45 TVIIGGGCVGVSLAYHLAKAGMRDVVL-----LEKSELTAGSTWHAAGLT--TYFHPGIN 97 V++G G +G+S A LA+ G +L + S T S W A T G Sbjct: 9 VVVLGSGVIGLSSALILARKGYSVHILARDLPEDVSSQTFASPWAGANWTPFMTLTDGPR 68 Query: 98 LKKIHYDSIKLYERLEEETGQVVGFHQPGSIRLATTPERVDEFKYQMTRTNWHATEQYII 157 K + K + L + G+ R A + + +W+ Sbjct: 69 QAKWEESTFKKWVELVPTGHAMWL---KGTRRFAQNEDGLL--------GHWYKDITPNY 117 Query: 158 EPEKIHELFPLLNMDKILAGLYNPGDGHIDPYSLTMALATGARKYGVLLKYPAPVTSLKP 217 P E P + Y+ H Y LA +K G VTSL+ Sbjct: 118 RPLPSSECPPGA-----IGVTYDTLSVHAPKY--CQYLARELQKLGAT-FERRTVTSLEQ 169 Query: 218 RPDGTWDVETPQGSVRANRIVNAAGFWAREVGKMIGLDHPLIPVQHQYVVTSTIPEVKAL 277 DG A+ +VNA G A+ + + D P++ Q V+ + + + Sbjct: 170 AFDG------------ADLVVNATGLGAKSIAGID--DQAAEPIRGQTVLVKSPCKRCTM 215 Query: 278 KRELPVLRDLEGSYYLRQERDGLLF 302 P Y+ G + Sbjct: 216 DSSDPAS-----PAYIIPRPGGEVI 235 >1F8S-A nrPDB Length = 498 Score = 41.0 bits (94), Expect = 0.002, Method: Composition-based stats. Identities = 46/286 (16%), Positives = 83/286 (29%), Gaps = 69/286 (24%) Query: 45 TVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAG-STWHAAGLTTYFHPGIN------ 97 VI+G G G+S AY LA AG + VL T+ Y + G Sbjct: 36 VVIVGAGMAGLSAAYVLAGAGHQVTVLEASERPGGRVRTYRNEEAGWYANLGPMRLPEKH 95 Query: 98 ------LKKIHYDSIKLYERLEEETGQVVGFHQ--------PGSIRLATTPER------- 136 ++K + + + + + PG ++ P Sbjct: 96 RIVREYIRKFDLRLNEFSQENDNAWYFIKNIRKKVGEVKKDPGLLKYPVKPSEAGKSAGQ 155 Query: 137 ---------VDEFKY----------QMTRTNWHATEQYIIEPEKIHELFPLLNMDKILAG 177 V+E K T + ++ + P + + LLN D Sbjct: 156 LYEESLGKVVEELKRTNCSYILNKYDTYSTKEYLIKEGDLSPGAVDMIGDLLNEDSGYYV 215 Query: 178 LYNPGDGHIDPYSLTMALATGA-----------RKYGVLLKYPAPVTSLKPRPDGTWDV- 225 + H D ++ R + + A V ++ V Sbjct: 216 SFIESLKHDDIFAYEKRFDEIVDGMDKLPTAMYRDIQDKVHFNAQVIKIQQNDQKVTVVY 275 Query: 226 -----ETPQGSVRANRIVNAAGFWAREVGKMIGLDHPLIPVQHQYV 266 ETP SV A+ ++ ++I + PL+P + + Sbjct: 276 ETLSKETP--SVTADYVIVCT---TSRAVRLIKFNPPLLPKKAHAL 316 >4BK3-A nrPDB Length = 424 Score = 41.0 bits (94), Expect = 0.002, Method: Composition-based stats. Identities = 38/230 (16%), Positives = 68/230 (29%), Gaps = 21/230 (9%) Query: 190 SLTMALATGARKYGVLLKYPAPVTSLKPRPDGTWDVETPQGSVRANRIVNAAGFWAREVG 249 L L AR G L VT + D V T G I + Sbjct: 112 DLHATLVDAARAAGAELHTGVTVTDVITEGDKAI-VSTDDGRTHEADIALGMDGLKSRLR 170 Query: 250 KMIGLDHPLIPVQHQYVVTSTIPEVKALKRELPVLRDLEGSYYLRQERDGLLFGPYESQE 309 + I D P+ Y T+ +V+ + V+ + + Q L G + Sbjct: 171 EKISGDEPVSSGYAAYRGTTPYRDVELDEDIEDVVGYIGPRCHFIQYP---LRGGEMLNQ 227 Query: 310 KMKLQASWVAHGVPPGFGKELFESDLDRITEHVEAAMEMVPVLKKADIINIVNGPITYSP 369 ++ +G+ G E E E+V ++ + + P Sbjct: 228 VAVFESPGFKNGIENWGGPEELEQAYAHCHENVRRGIDYL-------WKDRWWPMYDREP 280 Query: 370 -----DILPMV---GPHQGVRNYWVAIGFGYGIIHAGGVGKYLSDWILHG 411 D ++ H ++ ++A G I A + Y ++ G Sbjct: 281 IENWVDGRMILLGDAAHPPLQ--YLASGAVMAIEDAKCLADYAAEDFSTG 328 >5MOG-A nrPDB Length = 497 Score = 40.6 bits (93), Expect = 0.003, Method: Composition-based stats. Identities = 18/75 (24%), Positives = 31/75 (41%), Gaps = 8/75 (10%) Query: 36 PPEWKDRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAG--------STWHAAG 87 + + VI G G G+S A +LA AG + ++L + L W+ G Sbjct: 11 SEQPTKPLQVVIAGAGLAGLSTAKYLADAGHKPILLEARDVLGGKIAAWKDEDGDWYETG 70 Query: 88 LTTYFHPGINLKKIH 102 L +F N++ + Sbjct: 71 LHIFFGAYPNIQNLF 85 >2BXR-A nrPDB Length = 527 Score = 39.4 bits (90), Expect = 0.006, Method: Composition-based stats. Identities = 19/78 (24%), Positives = 34/78 (43%), Gaps = 1/78 (1%) Query: 43 AETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGS-TWHAAGLTTYFHPGINLKKI 101 + V+IGGG G+S A L + G+ +VL + + + T + G + Sbjct: 14 FDVVVIGGGISGLSAAKLLTEYGVSVLVLEARDRVGGRTYTIRNEHVDYVDVGGAYVGPT 73 Query: 102 HYDSIKLYERLEEETGQV 119 ++L + L ET +V Sbjct: 74 QNRILRLSKELGIETYKV 91 >4Y4M-A nrPDB Length = 290 Score = 39.4 bits (90), Expect = 0.006, Method: Composition-based stats. Identities = 14/31 (45%), Positives = 20/31 (64%) Query: 43 AETVIIGGGCVGVSLAYHLAKAGMRDVVLLE 73 A+ VI+G G G++ A +LAK G + VVL Sbjct: 60 ADVVIVGAGPSGLTCARYLAKEGFKVVVLER 90 >1NAA-A nrPDB Length = 541 Score = 39.4 bits (90), Expect = 0.007, Method: Composition-based stats. Identities = 17/77 (22%), Positives = 31/77 (40%), Gaps = 7/77 (9%) Query: 43 AETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKIH 102 + +I+G G G+ A L++AG + ++L ST G P + Sbjct: 3 YDYIIVGAGPGGIIAADRLSEAGKKVLLLERGGP----STKQTGGTYVA--PWATSSGLT 56 Query: 103 -YDSIKLYERLEEETGQ 118 +D L+E L ++ Sbjct: 57 KFDIPGLFESLFTDSNP 73 >5MJK-A nrPDB Length = 327 Score = 39.4 bits (90), Expect = 0.007, Method: Composition-based stats. Identities = 21/81 (25%), Positives = 35/81 (43%), Gaps = 4/81 (4%) Query: 33 PPSPPEWKDRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAGLTTYF 92 P + + + VIIG G G++ A + A++ M+ +LLE+ A Sbjct: 15 PRGSHMTEKKYDVVIIGSGPAGMTAAMYTARSEMK-TLLLERGVPGGQMNNTAE---IEN 70 Query: 93 HPGINLKKIHYDSIKLYERLE 113 +PG S+K+ E LE Sbjct: 71 YPGYETIMGPELSMKMAEPLE 91 >5UWY-A nrPDB Length = 308 Score = 39.0 bits (89), Expect = 0.008, Method: Composition-based stats. Identities = 17/72 (23%), Positives = 34/72 (47%), Gaps = 4/72 (5%) Query: 43 AETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKIH 102 +T+IIG G G++ A + A++ + V ++E+ +PG + Sbjct: 5 YDTLIIGSGPAGMTAALYAARSNL-SVAIIEQGAPGG---QMNNTFDIENYPGYDHISGP 60 Query: 103 YDSIKLYERLEE 114 ++K+YE LE+ Sbjct: 61 ELAMKMYEPLEK 72 >4UIR-A nrPDB Length = 646 Score = 39.0 bits (89), Expect = 0.008, Method: Composition-based stats. Identities = 22/93 (23%), Positives = 41/93 (44%), Gaps = 4/93 (4%) Query: 21 PSSAGLREGQESPPSPPEWKDRAETVIIGGGCVGVSLAYHLAKAG---MRDVVLLEKSEL 77 P S + Q + P + D ++ IIG G G+S AY+ + G +++ LE+ + Sbjct: 41 PFSDQIGNYQRNKGIPVQSYDNSKIYIIGSGIAGMSAAYYFIRDGHVPAKNITFLEQLHI 100 Query: 78 TAGSTWHAAGLTTYFHPGINLKKIHYDSIKLYE 110 GS AG T + +++ L++ Sbjct: 101 DGGSLD-GAGNPTDGYIIRGGREMDMTYENLWD 132 >1O5W-A nrPDB Length = 534 Score = 38.6 bits (88), Expect = 0.010, Method: Composition-based stats. Identities = 17/78 (21%), Positives = 34/78 (43%), Gaps = 1/78 (1%) Query: 43 AETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGS-TWHAAGLTTYFHPGINLKKI 101 + V+IGGG G++ A L++ + +VL + + + T + G + Sbjct: 22 FDVVVIGGGISGLAAAKLLSEYKINVLVLEARDRVGGRTYTVRNEHVKWVDVGGAYVGPT 81 Query: 102 HYDSIKLYERLEEETGQV 119 ++L + L ET +V Sbjct: 82 QNRILRLSKELGIETYKV 99 >3KVE-A nrPDB Length = 486 Score = 38.6 bits (88), Expect = 0.012, Method: Composition-based stats. Identities = 49/287 (17%), Positives = 89/287 (31%), Gaps = 71/287 (24%) Query: 45 TVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAG--STWHAAGLTTYFHPGI------ 96 V++G G G+S AY LA AG + V +LE SE G T + Y + G Sbjct: 36 VVVVGAGMSGLSAAYVLAGAGHK-VTVLEASERAGGRVRTHRNSKEGWYANLGPMRIPEK 94 Query: 97 -------------NLKKIHYDSIKLYE---RLEEETGQVVGFHQPGSIRLATTPER---- 136 NL + ++ + + + G+V PG ++ P Sbjct: 95 HRIVREYIRKFGLNLNEFSQENDNAWYFIKNIRKRVGEVN--KDPGLLKYPVKPSEEGKS 152 Query: 137 ------------VDEFKY----------QMTRTNWHATEQYIIEPEKIHELFPLLNMDKI 174 V + K T + ++ + P + + LLN D Sbjct: 153 AGQLYEESLGSAVKDLKRTNCSYILNKYDTYSTKEYLIKEGNLSPGAVDMIGDLLNEDSG 212 Query: 175 LAGLYNPGDGHIDPYSLTMALATGA-----------RKYGVLLKYPAPVTSLKPRPDGTW 223 + H D ++ R +K+ A V ++ + Sbjct: 213 YYVSFIESLKHDDIFAYEKRFDEIVGGMDQLPTSMYRAIEEKVKFNARVIKIQQNANQVT 272 Query: 224 -DVETPQ---GSVRANRIVNAAGFWAREVGKMIGLDHPLIPVQHQYV 266 +TP+ S A+ ++ + I + PL P + + Sbjct: 273 VTYQTPEKDTSSNTADYVIVCT---TSRAARRIQFEPPLPPKKQHAL 316 >2JB2-A nrPDB Length = 489 Score = 38.6 bits (88), Expect = 0.013, Method: Composition-based stats. Identities = 24/166 (14%), Positives = 44/166 (26%), Gaps = 22/166 (13%) Query: 40 KDRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAGLTTYFHPGINLK 99 K V++GGG G+ A+ L KAG + VL ++ G Sbjct: 9 KGSHSVVVLGGGPAGLCSAFELQKAGYKVTVLEARTRPGGR--------VWTARGGSEET 60 Query: 100 KIHYDSIKLYERLEEETGQVVGFHQPGSIRLATTPERVDEFKYQMTRTNWHATEQYIIEP 159 + ++ K F + + T R+ + + E Sbjct: 61 DLSGETQK------------CTFSEGHFYNVGAT--RIPQSHITLDYCRELGVEIQGFGN 106 Query: 160 EKIHELFPLLNMDKILAGLYNPGDGHIDPYSLTMALATGARKYGVL 205 + + + + D + L A G L Sbjct: 107 QNANTFVNYQSDTSLSGQSVTYRAAKADTFGYMSELLKKATDQGAL 152 >3ABT-A nrPDB Length = 662 Score = 38.3 bits (87), Expect = 0.015, Method: Composition-based stats. Identities = 23/124 (18%), Positives = 42/124 (33%), Gaps = 8/124 (6%) Query: 34 PSPPEWKDRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAGLTTYFH 93 P P K + +IIG G G++ A L GM +L + + G Sbjct: 101 PLPT--KKTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFRKGNYVADL 158 Query: 94 P-----GINLKKIHYDSIKLYERLEEETGQVVGFHQPGSIRLATTPERVD-EFKYQMTRT 147 G+ + S ++ L + + + G E V+ EF + T Sbjct: 159 GAMVVTGLGGNPMAVVSKQVNMELAKIKQKCPLYEANGQAVPKEKDEMVEQEFNRLLEAT 218 Query: 148 NWHA 151 ++ + Sbjct: 219 SYLS 222 >3II4-A nrPDB Length = 466 Score = 38.3 bits (87), Expect = 0.015, Method: Composition-based stats. Identities = 38/268 (14%), Positives = 80/268 (29%), Gaps = 27/268 (10%) Query: 179 YNPGDGHIDPYSLTMALATGARKYGVLLKYPAPVTSLKPRPDGTWDVETPQGS---VRAN 235 + P + ++ + +K GV + V S+ T G ++A Sbjct: 204 FLPRALPNEDADVSKEIEKQFKKLGVTILTATKVESIADGGSQVTVTVTKDGVAQELKAE 263 Query: 236 RIVNAAGFWAREVG---KMIGLDHPLIPVQHQYVVTSTIPEVKALKRELPVLRDLEGSYY 292 +++ A GF G G+ + + +R G Y Sbjct: 264 KVLQAIGFAPNVEGYGLDKAGVAL----TDRKAIGVDD------------YMRTNVGHIY 307 Query: 293 LRQERDGLLFGPYESQEKMKLQASWVAHGVPPGFGKELFESDLDRITEHVEAAMEMVPVL 352 + +GLL + ++ + + A +A G +V A+ + Sbjct: 308 AIGDVNGLLQLAHVAEAQGVVAAETIAGAETLTLGDHRMLPRATFCQPNV-ASFGLTEQQ 366 Query: 353 KKADIINIVNGPITYSPDILPM-VGPHQGVRNYWVAIGFGY---GIIHAGGVGKYLSDWI 408 + + ++V ++ + VG G G G + V + L + Sbjct: 367 ARNEGYDVVVAKFPFTANAKAHGVGDPSGFVKLVADAKHGELLGGHLVGHDVAELLPELT 426 Query: 409 LHGEPPFDLIELDPNRYGKWTTTQYTEA 436 L EL N + T ++ + Sbjct: 427 LAQRWDLTASELARNVHTHPTMSEALQE 454 >2CVJ-A nrPDB Length = 180 Score = 37.9 bits (86), Expect = 0.020, Method: Composition-based stats. Identities = 23/102 (22%), Positives = 43/102 (42%), Gaps = 6/102 (5%) Query: 44 ETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHA---AGLTTYFHPGINLKK 100 + +++GGG G+S A LA+AG++ V++L+ GL L++ Sbjct: 3 DVIVVGGGPSGLSAALFLARAGLK-VLVLDGGRSKVKGVSRVPNYPGLLDEPSGEELLRR 61 Query: 101 IHYDSIKLYERLEEETGQVVGFHQPGSIRLATTPERVDEFKY 142 + + + E G V G G + T E V++ + Sbjct: 62 LEAHARR--YGAEVRPGVVKGVRDMGGVFEVETEEGVEKAER 101 >2VVL-G nrPDB Length = 495 Score = 37.5 bits (85), Expect = 0.024, Method: Composition-based stats. Identities = 18/70 (25%), Positives = 30/70 (42%), Gaps = 3/70 (4%) Query: 29 GQESPPSPPEWKDR---AETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHA 85 G SPP+ E D+ + ++IGGG G++ L AG + ++L + + S Sbjct: 23 GVISPPTNIEDTDKDGPWDVIVIGGGYCGLTATRDLTVAGFKTLLLEARDRIGGRSWSSN 82 Query: 86 AGLTTYFHPG 95 Y G Sbjct: 83 IDGYPYEMGG 92 >5L3D-A nrPDB Length = 852 Score = 37.5 bits (85), Expect = 0.028, Method: Composition-based stats. Identities = 23/124 (18%), Positives = 42/124 (33%), Gaps = 8/124 (6%) Query: 34 PSPPEWKDRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAGLTTYFH 93 P P K + +IIG G G++ A L GM +L + + G Sbjct: 272 PLPT--KKTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFRKGNYVADL 329 Query: 94 P-----GINLKKIHYDSIKLYERLEEETGQVVGFHQPGSIRLATTPERVD-EFKYQMTRT 147 G+ + S ++ L + + + G E V+ EF + T Sbjct: 330 GAMVVTGLGGNPMAVVSKQVNMELAKIKQKCPLYEANGQAVPKEKDEMVEQEFNRLLEAT 389 Query: 148 NWHA 151 ++ + Sbjct: 390 SYLS 393 >3WE0-A nrPDB Length = 580 Score = 37.1 bits (84), Expect = 0.030, Method: Composition-based stats. Identities = 16/51 (31%), Positives = 24/51 (47%), Gaps = 1/51 (1%) Query: 35 SPPEWKDRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHA 85 S P + E I+G G G+ AY L K G++ V + E S++ A Sbjct: 58 SIPAARHGEEVAIVGAGIAGLVAAYELMKLGLKPV-VYEASKMGGRLRSQA 107 >1MDA-H nrPDB Length = 368 Score = 37.1 bits (84), Expect = 0.034, Method: Composition-based stats. Identities = 25/99 (25%), Positives = 35/99 (35%), Gaps = 4/99 (4%) Query: 385 WVAIGFGYGIIHAGGVGKYLS-DWILHGEPPFDLIELDPNRYGKWTTTQYTEAKARESYG 443 WV+ G G+ +G +LS H F L R K T Y E ++ Sbjct: 49 WVSCA-GCGVTLGHSLGAFLSLAVAGHSGSDFALASTSFARSAKGKRTDYVEVFDPVTFL 107 Query: 444 FNNIVGYPKEERFAGRPTQRVSGLYKILESKCSMGFHAG 482 + P RF+ P RV + S C + F G Sbjct: 108 PIADIELPDAPRFSVGP--RVHIIGNCASSACLLFFLFG 144 >5ZYN-B nrPDB Length = 471 Score = 37.1 bits (84), Expect = 0.034, Method: Composition-based stats. Identities = 37/218 (16%), Positives = 73/218 (33%), Gaps = 38/218 (17%) Query: 45 TVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKIHYD 104 V+IG G G++ + L VVLL+K+ G++ A+ H D Sbjct: 7 VVVIGSGLAGLTTSNRLISKYRIPVVLLDKAASIGGNSIKASSGINGAHTDTQQNLKVMD 66 Query: 105 SIKLYERLEEETGQVVGFHQPGSIRLATTPERVDEFKYQMTRTNWHATEQYIIEPEKIHE 164 + +L+ L++ G G L + + W TE + Sbjct: 67 TPELF--LKDTLHSAKG---RGVPSLMDKLTKESKS-----AIRWLQTEFDL-------- 108 Query: 165 LFPLLNMDKILAGLYNPG----DGHIDP-YSLTMALATGAR------KYGVLLKYPAPVT 213 L++ L G P G + P + + AL+ + V + + V Sbjct: 109 ---KLDLLAQLGGHSVPRTHRSSGKLPPGFEIVQALSKKLKDISSKDSNLVQIMLNSEVV 165 Query: 214 SLKPRPDGTW------DVETPQGSVRANRIVNAAGFWA 245 ++ G D + ++++ +V +G + Sbjct: 166 DIELDNQGHVTGVVYMDENGNRKIMKSHHVVFCSGGFG 203 >1REO-A nrPDB Length = 486 Score = 37.1 bits (84), Expect = 0.036, Method: Composition-based stats. Identities = 48/287 (16%), Positives = 88/287 (30%), Gaps = 71/287 (24%) Query: 45 TVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAG--STWHAAGLTTYFHPGI------ 96 V++G G G+S AY L+ AG + V +LE SE G T+ Y + G Sbjct: 36 VVVVGAGMSGLSAAYVLSGAGHQ-VTVLEASERAGGRVRTYRNDKEDWYANLGPMRLPEK 94 Query: 97 -------------NLKKIHYDSIKLYE---RLEEETGQVVGFHQPGSIRLATTPER---- 136 L + ++ + + + G+V PG ++ P Sbjct: 95 HRIVREYIRKFGLQLNEFSQENDNAWYFIKNIRKRVGEVK--KDPGVLKYPVKPSEEGKS 152 Query: 137 ------------VDEFKY----------QMTRTNWHATEQYIIEPEKIHELFPLLNMDKI 174 V+E K T + ++ + P + + L+N D Sbjct: 153 AGQLYEESLGKVVEELKRTNCSYILNKYDTYSTKEYLLKEGNLSPGAVDMIGDLMNEDSG 212 Query: 175 LAGLYNPGDGHIDPYSLTMALATGA-----------RKYGVLLKYPAPVTSLKPRPDGTW 223 + H D ++ R + A V ++ + Sbjct: 213 YYVSFPESLRHDDIFAYEKRFDEIVGGMDKLPTSMYRAIEEKVHLNAQVIKIQKNAEKVT 272 Query: 224 DV-ETPQ---GSVRANRIVNAAGFWAREVGKMIGLDHPLIPVQHQYV 266 V +TP SV A+ ++ + I + PL P + + Sbjct: 273 VVYQTPAKEMASVTADYVIVCT---TSRATRRIKFEPPLPPKKAHAL 316 >1SEZ-A nrPDB Length = 504 Score = 37.1 bits (84), Expect = 0.037, Method: Composition-based stats. Identities = 13/48 (27%), Positives = 20/48 (41%), Gaps = 2/48 (4%) Query: 34 PSPPEWKDRA--ETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTA 79 PS E K + +IG G G++ AY L G+ V + + Sbjct: 3 PSAGEDKHSSAKRVAVIGAGVSGLAAAYKLKIHGLNVTVFEAEGKAGG 50 >2IVE-A nrPDB Length = 478 Score = 36.7 bits (83), Expect = 0.038, Method: Composition-based stats. Identities = 13/42 (30%), Positives = 21/42 (50%) Query: 44 ETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHA 85 ++GGG G+++A+HL G V+L + L HA Sbjct: 18 NVAVVGGGISGLAVAHHLRSRGTDAVLLESSARLGGAVGTHA 59 >3JSK-A nrPDB Length = 344 Score = 36.7 bits (83), Expect = 0.040, Method: Composition-based stats. Identities = 17/95 (17%), Positives = 30/95 (31%), Gaps = 5/95 (5%) Query: 44 ETVIIGGGCVGVSLAYHLAK-AGMRDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKIH 102 + VI+G G G+S AY L+ + ++E G W G + Sbjct: 81 DIVIVGAGSCGLSAAYVLSTLRPDLRITIVEAGVAPGGGAW-LGGQLFSAMVMRKPADVF 139 Query: 103 YDSIKLYERLEEE---TGQVVGFHQPGSIRLATTP 134 D + + E + F ++ P Sbjct: 140 LDEVGVPYEDEGDYVVVKHAALFTSTVLSKVLQRP 174 >3IHG-A nrPDB Length = 535 Score = 36.7 bits (83), Expect = 0.043, Method: Composition-based stats. Identities = 10/31 (32%), Positives = 20/31 (64%) Query: 44 ETVIIGGGCVGVSLAYHLAKAGMRDVVLLEK 74 + +++G G G+S A LA+ G+R +V+ + Sbjct: 7 DVLVVGAGLGGLSTAMFLARQGVRVLVVERR 37 >1JWB-B nrPDB Length = 249 Score = 36.7 bits (83), Expect = 0.044, Method: Composition-based stats. Identities = 11/64 (17%), Positives = 28/64 (43%) Query: 38 EWKDRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAGLTTYFHPGIN 97 E + +I+G G +G + + +LA AG+ ++ LL+ ++ + + Sbjct: 27 EALKDSRVLIVGLGGLGCAASQYLASAGVGNLTLLDFDTVSLSNLQRQTLHSDATVGQPK 86 Query: 98 LKKI 101 ++ Sbjct: 87 VESA 90 >4EIQ-A nrPDB Length = 549 Score = 36.7 bits (83), Expect = 0.044, Method: Composition-based stats. Identities = 46/221 (20%), Positives = 74/221 (33%), Gaps = 48/221 (21%) Query: 44 ETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKIHY 103 + +I+GGG VG++LA LA + +V+ AG T HP + I Sbjct: 28 DVLILGGGPVGMALALDLAHRQVGHLVVD-------------AGDGTITHP--KVSTIGP 72 Query: 104 DSIKLYERLEEETGQVVGFHQPGSIRLATTPERVDEFKYQMTRTNWHATEQYIIEPEKIH 163 S++L+ R V + H + + H Sbjct: 73 RSMELFRRW-----------------------GVAKQIRTAGWPGDHPLDAAWVTRVGGH 109 Query: 164 ELF--PLLNMDKILAGLYNPGDGHIDPYSLTMALATGARKYGVLLKYPAPVTSLKPRPDG 221 E++ PL D + P I P A G L+ + + S + R D Sbjct: 110 EVYRIPLGTADTRATPEHTPEPDAICPAH--WLAPLLAEAVGERLRTRSRLDSFEQRDDH 167 Query: 222 T----WDVET-PQGSVRANRIVNAAGFWAREVGKMIGLDHP 257 D+ T +V A +V G + K +G+D P Sbjct: 168 VRATITDLRTGATRAVHARYLVACDGA-SSPTRKALGIDAP 207 >3MJ4-A nrPDB Length = 397 Score = 36.7 bits (83), Expect = 0.045, Method: Composition-based stats. Identities = 20/92 (21%), Positives = 38/92 (41%), Gaps = 3/92 (3%) Query: 27 REGQESPPSPPEWKDRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAA 86 R Q + + + + +I+G G G LA LA +G R +++ + + + Sbjct: 14 RTEQTNTTNEQQESKGFDYLIVGAGFAGSVLAERLASSGQRVLIVDRRPHIGGNAYDCYD 73 Query: 87 GLTTYFHP-GINLKKIHYDSIKLYERLEEETG 117 HP G ++ H +S ++E L T Sbjct: 74 DAGVLIHPYGPHI--FHTNSKDVFEYLSRFTE 103 >3UP5-A nrPDB Length = 545 Score = 36.7 bits (83), Expect = 0.047, Method: Composition-based stats. Identities = 23/124 (18%), Positives = 48/124 (38%), Gaps = 10/124 (8%) Query: 44 ETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAGLTTYFHPGINL-KKIH 102 + V+IG G G+ A+ + +AGM+ + + ++ W+ +PG L + + Sbjct: 11 DAVVIGAGVTGIYQAFLINQAGMKVLGIEAGEDVGGTWYWN-------RYPGCRLDTESY 63 Query: 103 YDSIKLYERLEEETGQVVGF-HQPGSIRLATTPERVDEFKYQMTRTNWHATEQYIIEPEK 161 + + E F QP +R + + R N T +E ++ Sbjct: 64 AYGYFALKGIIPEWEWSENFASQPEMLRYVNRAADAMDVRKHY-RFNTRVTAARYVENDR 122 Query: 162 IHEL 165 + E+ Sbjct: 123 LWEV 126 >4K2X-A nrPDB Length = 523 Score = 36.7 bits (83), Expect = 0.048, Method: Composition-based stats. Identities = 44/223 (19%), Positives = 70/223 (31%), Gaps = 57/223 (25%) Query: 42 RAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKI 101 R + VI G G G+ LA L AG R +VL +E S + Sbjct: 22 RYDVVIAGAGPTGLMLACELRLAGARTLVLERLAEPVDFS---------------KALGV 66 Query: 102 HYDSIKLYE--RLEEETGQVVGFHQPGSIRLATTPERVDEFKYQMTRTNWHATEQYIIEP 159 H +++L + L E + G+ P F + + Sbjct: 67 HARTVELLDMRGLGEGFQAEAPKLRGGNFASLGVPLDFSSFDTRHPYALF---------- 116 Query: 160 EKIHELFPLLNMDKILAGLYNPGDGHIDPYSLTMALATGARKYGVLLKYPAPVTSLKPRP 219 P + +++L G A + G L+ VT+L+ Sbjct: 117 ------VPQVRTEELLTG--------------------RALELGAELRRGHAVTALEQDA 150 Query: 220 DGTW-DVETPQGSVRAN--RIVNAAGFWAREVGKMIGLDHPLI 259 DG V P+G +V G V K++G+D P Sbjct: 151 DGVTVSVTGPEGPYEVECAYLVGCDGG-GSTVRKLLGIDFPGQ 192 >3L1R-A nrPDB Length = 478 Score = 36.7 bits (83), Expect = 0.048, Method: Composition-based stats. Identities = 12/39 (30%), Positives = 24/39 (61%) Query: 45 TVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTW 83 +++G G G+S A L++AG+ D+++LE ++ G Sbjct: 7 VIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRMH 45 >4JNQ-A nrPDB Length = 345 Score = 36.7 bits (83), Expect = 0.049, Method: Composition-based stats. Identities = 50/364 (13%), Positives = 102/364 (28%), Gaps = 47/364 (12%) Query: 25 GLREGQESPPSPPEWKDRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWH 84 G E Q P + A ++IG G G + A + A+A ++ VV+ + Sbjct: 10 GTLEAQTQGPGSMT-QRHAPVIVIGSGPAGYTAAIYAARAMLKPVVI---------AGLQ 59 Query: 85 AAGLTTYFHPGINLKKIHYDSIKLYERLEEETGQVVGFHQPGSIRLATTPERVDEFKYQM 144 G N + + Q + V F+ + Sbjct: 60 QGGQLMITTDVENYPGYAEPVQGPWMMEQMARQAENVGAQIVHDIITEVETTVRPFRLKG 119 Query: 145 TRTNWHATEQYIIEPEKIHELFPLLNMDKILAGLYNPGDGHIDPYSLTMALATGARKYGV 204 + + +I + L ++ G G + + + V Sbjct: 120 DSGTIYTCDA-LIIATGAQAKWLGLESEQTFMG------GGVSACATCDGFFYRGKDVVV 172 Query: 205 LLKYPAPVTS--LKPRPDGTWDVETPQGSVRANRIV--------NAAGFWAREVGKMIGL 254 + V + + + RA +I+ N + W + +++G Sbjct: 173 VGGGNTAVEEALYLSHIAKSVTIVHRRDGFRAEKIMQDRLLSRENVSVVWNSVIDEILGT 232 Query: 255 D-HP-----LIPVQHQYVVTSTIPEVKALKRELPVLRDLEGSYY---LRQERDGLLFGPY 305 + P + V+ + +VT E + + S + L+Q+ +G L+ Sbjct: 233 EARPPMGATVTGVRLKNIVTGETQERATHGVFIAIGHAPAVSLFEGKLKQKPNGYLWTAP 292 Query: 306 ESQEKMKLQASWVAHGVPPGFGKELFESDLDRITEHVEAAMEMVPVLKKADIINIVNGPI 365 A VP F D+ R A M + L+ + Sbjct: 293 ----------DSTATDVPGIFAAGDVTDDIYR-QAVTAAGMGCMAALEAERWLAAQEPLH 341 Query: 366 TYSP 369 + Sbjct: 342 EAAE 345 >5TUK-A nrPDB Length = 408 Score = 36.3 bits (82), Expect = 0.057, Method: Composition-based stats. Identities = 15/101 (14%), Positives = 30/101 (29%), Gaps = 5/101 (4%) Query: 45 TVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKIHYD 104 ++IG G G ++ Y L + G +++ + L HA + I+ Sbjct: 28 ILVIGAGIAGPAVCYWLRRFGFSPILVERCANL--RKGGHAVDIRGVAIDLAKSMGIYKK 85 Query: 105 SIKLYERLEEETGQVVG---FHQPGSIRLATTPERVDEFKY 142 + ++E H+ R E Sbjct: 86 ICNMRTQVELGRYVDAEGNILHEEKGERFGFREGDDIEILR 126 >4B1B-A nrPDB Length = 542 Score = 36.3 bits (82), Expect = 0.063, Method: Composition-based stats. Identities = 20/103 (19%), Positives = 36/103 (34%), Gaps = 12/103 (11%) Query: 43 AETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAGL---------TTYFH 93 + V+IGGG G++ A A G R ++ + G+ W G + Sbjct: 43 YDYVVIGGGPGGMASAKEAAAHGARVLLFDYVKPSSQGTKWGIGGTCVNVGCVPKKLMHY 102 Query: 94 PGINLKKIHYDSIK---LYERLEEETGQVVGFHQPGSIRLATT 133 G DS ++ L+ + ++V Q L + Sbjct: 103 AGHMGSIFKLDSKAYGWKFDNLKHDWKKLVTTVQSHIRSLNFS 145 >3BI4-A nrPDB Length = 516 Score = 36.3 bits (82), Expect = 0.064, Method: Composition-based stats. Identities = 45/295 (15%), Positives = 87/295 (29%), Gaps = 65/295 (22%) Query: 36 PPEWKDRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTA---------------- 79 P K +IIG G G+ A L + G++D ++LE + Sbjct: 5 SPAKKK---VIIIGAGIAGLKAASTLHQNGIQDCLVLEARDRVGGRLQTVTGYQGRKYDI 61 Query: 80 GSTWHAAGLTTYFHPG-----------------------INLKKIHYDSIKLYERL---E 113 G++WH LT + +L + E Sbjct: 62 GASWHHDTLTNPLFLEEAQLSLNDGRTRFVFDDDNFIYIDEERGRVDHDKELLLEIVDNE 121 Query: 114 EETGQVVGFHQPGSIRLATTPERVDEFKYQMTRTNWHATEQYIIEPEKIHEL-------F 166 + FHQ + ++ KY + R + +Q P+ L + Sbjct: 122 MSKFAELEFHQ--HLGVSDCSFFQLVMKYLLQRRQFLTNDQIRYLPQLCRYLELWHGLDW 179 Query: 167 PLLNMDKILAGLYNPGDGHIDPYSLTMALATGARKYGVLLKYPAPVTSLKPRPDGTWDVE 226 LL+ G ++ S+ +A + + L V S+ P V Sbjct: 180 KLLSAKDTYFGHQGRNAFALNYDSVVQRIAQSFPQNWLKL--SCEVKSITREPSKNVTVN 237 Query: 227 TPQGS-VRANRIVNAAGFWAREVGKMIGLDHPLIPVQHQYVVTSTIPEVKALKRE 280 G+ A+ ++ L+ + P ++ P +K + ++ Sbjct: 238 CEDGTVYNADYVIITV--------PQSVLNLSVQPEKNLRGRIEFQPPLKPVIQD 284 >4RPJ-A nrPDB Length = 399 Score = 35.9 bits (81), Expect = 0.069, Method: Composition-based stats. Identities = 20/131 (15%), Positives = 48/131 (36%), Gaps = 11/131 (8%) Query: 42 RAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAG-------LTTYFHP 94 R + ++G G G+++A +A + V++LE+ G+ + A H Sbjct: 7 RFDLFVVGSGFFGLTIAERVATQLDKRVLVLERRPHIGGNAYSEAEPQTGIEVHKYGAHL 66 Query: 95 GINLKKIHYDSIKLYERLEEETGQVVGFHQPGSIRLATTPERVDEFKYQMTRTNWHATEQ 154 K +D ++ + + +V H + + V +F + + + Sbjct: 67 FHTSNKRVWDYVRQFTDFTDYRHRVFAMHNGQAYQFPMGLGLVSQFFGKY----FTPEQA 122 Query: 155 YIIEPEKIHEL 165 + E+ E+ Sbjct: 123 RQLIAEQAAEI 133 >4IV9-A nrPDB Length = 557 Score = 35.9 bits (81), Expect = 0.069, Method: Composition-based stats. Identities = 15/39 (38%), Positives = 21/39 (53%) Query: 45 TVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTW 83 I+G G G+ A L +AG++DVVL E + G W Sbjct: 41 VAIVGAGISGLVAATELLRAGVKDVVLYESRDRIGGRVW 79 >3NK2-X nrPDB Length = 431 Score = 35.9 bits (81), Expect = 0.077, Method: Composition-based stats. Identities = 19/98 (19%), Positives = 34/98 (34%), Gaps = 1/98 (1%) Query: 43 AETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKIH 102 + +++GGG G+ A L AG + ++L L + + I +H Sbjct: 2 YDAIVVGGGFSGLKAARDLTNAGKKVLLLEGGERLGGRAYSRESRNVPGLRVEIGGAYLH 61 Query: 103 YDSI-KLYERLEEETGQVVGFHQPGSIRLATTPERVDE 139 +L L+ + S R P VD+ Sbjct: 62 RKHHPRLAAELDRYGIPTAAASEFTSFRHRLGPTAVDQ 99 >6J0Z-C nrPDB Length = 491 Score = 35.9 bits (81), Expect = 0.081, Method: Composition-based stats. Identities = 42/220 (19%), Positives = 72/220 (32%), Gaps = 59/220 (26%) Query: 43 AETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKIH 102 ++ V++G G G+ LA L AG+ VVL + +E + + Sbjct: 6 SDVVVVGAGPTGLMLAGELRLAGVSVVVLDKLAEP-----------------IKESRALG 48 Query: 103 YDSIKLYERLEEETGQVVGFHQPGSIRLATTPERVDEFKYQMTRTNWHATEQYIIEPEKI 162 + S + E + G + F + G I + YQ+ + Sbjct: 49 F-SARTIEEFAQR-GLMDRFGEVGVIPVGHF--GGVPLDYQVIEGGSYGARG-------- 96 Query: 163 HELFPLLNMDKILAGLYNPGDGHIDPYSLTMALATGARKYGVLLKYPAPVTSLKPRPDGT 222 P + IL G AR+ G ++ VT+++ Sbjct: 97 ---IPQARTEGILGGW--------------------ARELGAEVRRGYEVTAIEDTGTSV 133 Query: 223 WDVETPQG-----SVRANRIVNAAGFWAREVGKMIGLDHP 257 VE S+RA +V G + V K+ G+D P Sbjct: 134 T-VEAAGADGSPLSLRARYVVGCDGARSS-VRKLAGIDFP 171 >4Y4N-A nrPDB Length = 286 Score = 35.6 bits (80), Expect = 0.087, Method: Composition-based stats. Identities = 12/30 (40%), Positives = 19/30 (63%) Query: 44 ETVIIGGGCVGVSLAYHLAKAGMRDVVLLE 73 + I+GGG G++ A ++AK G + VVL Sbjct: 54 DVAIVGGGPSGLTAARYIAKEGYKVVVLER 83 >6CR0-A nrPDB Length = 440 Score = 35.6 bits (80), Expect = 0.10, Method: Composition-based stats. Identities = 7/42 (16%), Positives = 19/42 (45%) Query: 40 KDRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGS 81 + + +++G G G+ A L+ G +++ + L + Sbjct: 6 EKIYDAIVVGAGFSGLVAARELSAQGRSVLIIEARHRLGGRT 47 >3RHA-A nrPDB Length = 482 Score = 35.2 bits (79), Expect = 0.11, Method: Composition-based stats. Identities = 16/40 (40%), Positives = 23/40 (57%), Gaps = 1/40 (2%) Query: 44 ETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTW 83 + VI+G G G++ A L KAG+ V +LE + G TW Sbjct: 9 DVVIVGAGPSGLTAARELKKAGL-SVAVLEARDRVGGRTW 47 >4N9X-A nrPDB Length = 411 Score = 35.2 bits (79), Expect = 0.13, Method: Composition-based stats. Identities = 21/73 (28%), Positives = 33/73 (45%), Gaps = 5/73 (6%) Query: 41 DRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEK-SELTAGSTWHAAGLTTYFHPGINLK 99 + VI GGG VG++LA L +G+R VL ++ +E HA ++ L Sbjct: 2 QSFDVVIAGGGMVGLALACGLQGSGLRIAVLEKQAAEPQTLGKGHALRVSAINAASECL- 60 Query: 100 KIHYDSIKLYERL 112 I ++E L Sbjct: 61 ---LRHIGVWENL 70 >4USR-A nrPDB Length = 361 Score = 35.2 bits (79), Expect = 0.13, Method: Composition-based stats. Identities = 19/113 (16%), Positives = 37/113 (32%), Gaps = 23/113 (20%) Query: 33 PPSPPEWKDRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAGLTTYF 92 P PP + ++IGGG ++ AY L + + ++L E+ L Sbjct: 2 PAMPP----ILDVIVIGGGQAALTTAYFLRRTSLSYLLLDEQPGPGGAWLHAWDSLRL-- 55 Query: 93 HPGINLKKIHYDSIKLYERLEEETGQVVGFHQPGSIRLATTPERVDEFKYQMT 145 + SI + + +PG+ T V ++ + Sbjct: 56 -----FSPAAWSSIAGW--------PMPSPTEPGN----PTRNDVIDYLRRYE 91 >5EVY-X nrPDB Length = 438 Score = 34.8 bits (78), Expect = 0.15, Method: Composition-based stats. Identities = 63/428 (14%), Positives = 116/428 (27%), Gaps = 77/428 (17%) Query: 40 KDRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAGLTTYFHPGINLK 99 K +IGGG G +LA L+K+ +V L E + G Sbjct: 20 KSPLRVAVIGGGIAGTALALGLSKSSHVNVKLFETA-PAFGEIGAG-------------V 65 Query: 100 KIHYDSIKLYERLEEETGQVVGFHQPGSIRLATTPERVDEFKYQMTRTNWHATEQYIIEP 159 ++++ +RL + + T W E Sbjct: 66 SFGVNAVEAIQRLG--------------------IGELYKSVADSTPAPWQDI---WFEW 102 Query: 160 EKIHELFPLLNMDKILAGLYNPGDGHI------DPYSLTMALATGARKYGVLLKYPAPVT 213 H+ ++ PG G L L G G + Sbjct: 103 RHAHDA-------SLVGATVAPGIGQSSIHRADFIDMLEKRLPAGIASLGKHVVDYTE-- 153 Query: 214 SLKPRPDGTWDVETPQGSVRANRIVNAAGFWARE---VGKMIGLDHPLIP-------VQH 263 +G + A+ + A G + + + G D + P + Sbjct: 154 ----NAEGVTLNFADGSTYTADVAIAADGIKSSMRNTLLRAAGHD-AVHPQFTGTSAYRG 208 Query: 264 QYVVTSTIPEVKALKRELPVLRD------LEGSYYLRQERDGLLFGPYESQEKMKLQASW 317 ++ +A + +L +G + G L + Sbjct: 209 LVETSALREAYQAASLDEHLLNVPQMYLIEDGHVLTFPVKKGKLIIIVAFVSDRSVAKPQ 268 Query: 318 VAHGVPPGFGKELFESDLDRITEHVEAAMEMVPVLKKADI--INIVNGPITYSPDILPMV 375 P + L R EA ++ +K + ++ + TY + ++ Sbjct: 269 WPSD-QPWVRPATTDEMLHRFAGAGEAVKTLLTSIKSPTLWALHDFDPLPTYVHGRVALI 327 Query: 376 GPHQGVRNYWVAIGFGYGIIHAGGVGKYLSD-WILHGEPPFDLIELDPNRYGKWTTTQYT 434 G G G G+ A + + L + + P L D R G+ + Q T Sbjct: 328 GDAAHAMLPHQGAGAGQGLEDAYFMAELLGNPLHEASDIPALLEVYDDVRRGRASKVQLT 387 Query: 435 EAKARESY 442 +A E Y Sbjct: 388 SREAGELY 395 >5TUM-A nrPDB Length = 410 Score = 34.8 bits (78), Expect = 0.15, Method: Composition-based stats. Identities = 18/95 (18%), Positives = 34/95 (35%), Gaps = 11/95 (11%) Query: 41 DRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTW--------HAAGLTTYF 92 + ++IG G G ++ Y L + G V++ + + + G H A + Sbjct: 24 KNIKILVIGAGVAGPAVCYWLRRFGFSPVLIEKYASIRKGGQALDVRGIATHIAREMGIY 83 Query: 93 HPGINLKKIHYDSIKLYER---LEEETGQVVGFHQ 124 ++ + L EE G+ GF Q Sbjct: 84 DQICEMRTRIERGRFVDSSGKVLHEEQGEKFGFRQ 118 >3CGD-A nrPDB Length = 480 Score = 34.8 bits (78), Expect = 0.15, Method: Composition-based stats. Identities = 38/254 (14%), Positives = 79/254 (31%), Gaps = 61/254 (24%) Query: 42 RAETVIIGGGCVGVSLAYHLAKAGMR-DVVLLEKSE---------LTAGSTWHAAGLTTY 91 VIIGG G+S A + + +VV LEK E S A+ Sbjct: 36 SMNYVIIGGDAAGMSAAMQIVRNDENANVVTLEKGEIYSYAQCGLPYVISGAIASTEKLI 95 Query: 92 FHPGINLKKIHYDSIKLYERLEE-ETGQVVGFHQ-------------------------- 124 + + K+ + + +T + + + + Sbjct: 96 ARNVKTFRDKYGIDAKVRHEVTKVDTEKKIVYAEHTKTKDVFEFSYDRLLIATGVRPVMP 155 Query: 125 -------PGSIRLATTPERVDEFK----YQMTRTNWHATEQYIIEPEK----IHELFPLL 169 G L T P+ K ++ +E + + + ++ Sbjct: 156 EWEGRDLQGVHLLKTIPDAERILKTLETNKVEDVTIIGGGAIGLEMAETFVELGKKVRMI 215 Query: 170 NMDKILAGLYNPGDGHIDPYSLTMALATGARKYGVLLKYPAPVTSLKPRPDGTWDVETPQ 229 + + +Y DG + Y + A K+ + + V + K + VET + Sbjct: 216 ERNDHIGTIY---DGDMAEY-----IYKEADKHHIEILTNENVKAFKGN-ERVEAVETDK 266 Query: 230 GSVRANRIVNAAGF 243 G+ +A+ ++ + G Sbjct: 267 GTYKADLVLVSVGV 280 >4MOP-A nrPDB Length = 633 Score = 34.4 bits (77), Expect = 0.20, Method: Composition-based stats. Identities = 16/54 (29%), Positives = 26/54 (48%), Gaps = 7/54 (12%) Query: 33 PPSPPEWKD------RAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAG 80 PP P K + + VI+G G +G + A L AG + V + + E+ +G Sbjct: 31 PPLPGPDKKVPGMDIKYDVVIVGSGPIGCTYARELVGAGYK-VAMFDIGEIDSG 83 >3LOV-A nrPDB Length = 475 Score = 34.4 bits (77), Expect = 0.23, Method: Composition-based stats. Identities = 27/111 (24%), Positives = 44/111 (39%), Gaps = 14/111 (12%) Query: 46 VIIGGGCVGVSLAYHLAKAGMR-DVVLLEKSELTAG--STWHAAGLTTYFHPGINLKKIH 102 VI+GGG G++ AY+ +A ++ LLE E G +T+ G T P + + H Sbjct: 8 VIVGGGITGLAAAYYAERAFPDLNITLLEAGERLGGKVATYREDGFTIERGPDSYVARKH 67 Query: 103 -----YDSIKLYERLEEETGQVVGFHQPGSIRLATT------PERVDEFKY 142 ++I L E+L G + P +D F+ Sbjct: 68 ILTDLIEAIGLGEKLVRNNTSQAFILDTGGLHPIPKGAVMGIPTDLDLFRQ 118 >6N7F-A nrPDB Length = 453 Score = 34.4 bits (77), Expect = 0.23, Method: Composition-based stats. Identities = 12/38 (31%), Positives = 20/38 (52%), Gaps = 1/38 (2%) Query: 43 AETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAG 80 + ++IGGG G++ A A G + V+L E E+ Sbjct: 8 YDYIVIGGGSAGIASANRAAMHGAK-VLLAEGKEIGGT 44 >4IA5-A nrPDB Length = 591 Score = 34.0 bits (76), Expect = 0.25, Method: Composition-based stats. Identities = 16/57 (28%), Positives = 24/57 (42%), Gaps = 3/57 (5%) Query: 34 PSPPEWKDRAETVIIGGGCVGVSLAYHLAKAGM---RDVVLLEKSELTAGSTWHAAG 87 P P D+ IIG G G+S A L + ++ +LE+ + GS A Sbjct: 14 PKKPAGVDKKSAYIIGSGLAGLSTAVFLVRDAQMKGENIHILEELPVAGGSLDGADR 70 >2Q7V-A nrPDB Length = 325 Score = 34.0 bits (76), Expect = 0.31, Method: Composition-based stats. Identities = 13/41 (31%), Positives = 21/41 (51%), Gaps = 1/41 (2%) Query: 43 AETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTW 83 + VIIGGG G++ A + +A + ++LEK W Sbjct: 9 YDVVIIGGGPAGLTAAIYTGRAQL-STLILEKGMPGGQIAW 48 >2CUL-A nrPDB Length = 232 Score = 33.6 bits (75), Expect = 0.35, Method: Composition-based stats. Identities = 15/102 (14%), Positives = 32/102 (31%), Gaps = 6/102 (5%) Query: 43 AETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSE------LTAGSTWHAAGLTTYFHPGI 96 + +I+G G G A+ LA+ G+R +L + + L + L + Sbjct: 4 YQVLIVGAGFSGAETAFWLAQKGVRVGLLTQSLDAVMMPFLPPKPPFPPGSLLERAYDPK 63 Query: 97 NLKKIHYDSIKLYERLEEETGQVVGFHQPGSIRLATTPERVD 138 + + + + Y + G + V Sbjct: 64 DERVWAFHARAKYLLEGLRPLHLFQATATGLLLEGNRVVGVR 105 >4OVI-A nrPDB Length = 542 Score = 33.6 bits (75), Expect = 0.36, Method: Composition-based stats. Identities = 10/51 (19%), Positives = 22/51 (43%) Query: 29 GQESPPSPPEWKDRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTA 79 GQ + S + + + +++G G G+ Y L + G V+ ++ Sbjct: 3 GQTTVDSRRQPPEEVDVLVVGAGFSGLYALYRLRELGRSVHVIETAGDVGG 53 >1FEC-A nrPDB Length = 490 Score = 33.6 bits (75), Expect = 0.38, Method: Composition-based stats. Identities = 35/209 (16%), Positives = 65/209 (31%), Gaps = 43/209 (20%) Query: 41 DRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKK 100 + V+IG G G+ ++ A + V +++ + G +AA T + G KK Sbjct: 2 RAYDLVVIGAGSGGLEAGWNAASLHKKRVAVIDL-QKHHGPPHYAALGGTCVNVGCVPKK 60 Query: 101 IHYDSIKLYERLEEETGQVVGFHQPGSIRLATTPERVDEFKYQMTRTNWHATEQYIIEPE 160 + + + E GF E + R NW A Sbjct: 61 LMVTGANYMDTIRES----AGF--------------GWELDRESVRPNWKALIA------ 96 Query: 161 KIHELFPLLNMDKILAGLYNPGDGHIDPYSLTMALATGARKYGVLLKYPAPVTSLKPRPD 220 ++ +N G++ +G + +G L + P+ Sbjct: 97 AKNKAVSGIN--DSYEGMFADTEGLTFH-----------QGFGALQDNHTVLVRESADPN 143 Query: 221 GTWDVETPQGSVRANRIVNAAGFWAREVG 249 +ET I+ A G W + +G Sbjct: 144 SAV-LETLDTEY----ILLATGSWPQHLG 167 >1V59-A nrPDB Length = 478 Score = 33.3 bits (74), Expect = 0.46, Method: Composition-based stats. Identities = 11/40 (27%), Positives = 17/40 (42%) Query: 41 DRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAG 80 + VIIGGG G A A+ G + ++ +L Sbjct: 4 KSHDVVIIGGGPAGYVAAIKAAQLGFNTACVEKRGKLGGT 43 >3VH2-A nrPDB Length = 616 Score = 33.3 bits (74), Expect = 0.47, Method: Composition-based stats. Identities = 18/117 (15%), Positives = 40/117 (34%), Gaps = 6/117 (5%) Query: 41 DRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKK 100 + +++G G +G ++ L G+R + ++ ++ + A L + G + Sbjct: 326 KNTKVLLLGAGTLGCYVSRALIAWGVRKITFVDNGTVSYSNPVRQA-LYNFEDCGKPKAE 384 Query: 101 IHYDSIKLYERLEEETGQVVGFHQPGSIRLATTPERVDEFKYQMTRTNWHATEQYII 157 + S+K L + TG + + + R E II Sbjct: 385 LAAASLKRIFPLMDATG-----VKLSIPMIGHKLVNEEAQHKDFDRLRALIKEHDII 436 >3T7E-A nrPDB Length = 344 Score = 33.3 bits (74), Expect = 0.47, Method: Composition-based stats. Identities = 18/117 (15%), Positives = 40/117 (34%), Gaps = 6/117 (5%) Query: 41 DRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKK 100 + +++G G +G ++ L G+R + ++ ++ + A L + G + Sbjct: 37 KNTKVLLLGAGTLGCYVSRALIAWGVRKITFVDNGTVSYSNPVRQA-LYNFEDCGKPKAE 95 Query: 101 IHYDSIKLYERLEEETGQVVGFHQPGSIRLATTPERVDEFKYQMTRTNWHATEQYII 157 + S+K L + TG + + + R E II Sbjct: 96 LAAASLKRIFPLMDATG-----VKLSIPMIGHKLVNEEAQHKDFDRLRALIKEHDII 147 >4Z25-A nrPDB Length = 652 Score = 33.3 bits (74), Expect = 0.47, Method: Composition-based stats. Identities = 13/32 (40%), Positives = 19/32 (59%) Query: 44 ETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKS 75 + VIIG G G LA++LA+ ++LLE Sbjct: 8 DIVIIGAGAAGSLLAHYLARFSNMKIILLEAG 39 >1KSU-A nrPDB Length = 571 Score = 33.3 bits (74), Expect = 0.47, Method: Composition-based stats. Identities = 33/196 (16%), Positives = 66/196 (33%), Gaps = 24/196 (12%) Query: 56 SLAYHLAKAGMRDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKIHYDSIKLYERLEEE 115 S A +G + + L+EK + G+ AAG K DS +L + Sbjct: 140 SAAISATDSGAKVI-LIEKEPVIGGNAKLAAGGMNAAWTDQQKAKKITDSPELMFEDTMK 198 Query: 116 TGQVVGFHQPGSIRLATTPERVDEFKYQMTRTNWHATEQYIIEPEKIHELFPLLNMDKIL 175 GQ + + P +++ ++ + + MT T+ ++ ++ Sbjct: 199 GGQNI--NDPALVKVLSSHSK--DSVDWMTAMGADLTDVGMMGGASVNRA---------- 244 Query: 176 AGLYNPGDGHIDPYSLTMALATGARKYGVLLKYPAPVTSLKPRPDGTWDVETPQGSV--- 232 + P G + L A K + L+ + GT +G Sbjct: 245 ---HRPTGGAGVGAHVVQVLYDNAVKRNIDLRMNTRGIEVLKDDKGTVKGILVKGMYKGY 301 Query: 233 ---RANRIVNAAGFWA 245 +A+ ++ A G +A Sbjct: 302 YWVKADAVILATGGFA 317 >4OEN-A nrPDB Length = 223 Score = 33.3 bits (74), Expect = 0.54, Method: Composition-based stats. Identities = 12/57 (21%), Positives = 25/57 (43%) Query: 596 DLRWIEEAAVRGGYDVEIRNITDELGVLGVAGPYARRVLQKLTSEDLSDDVFKFLQT 652 D+ I+ A G+++EI N + + V A ++ ++ D F F ++ Sbjct: 29 DMELIKAIAKDQGFEIEITNPGFDAAISAVQAGQADGIIAGMSVTDARKATFDFSES 85 >3LXD-A nrPDB Length = 415 Score = 32.9 bits (73), Expect = 0.59, Method: Composition-based stats. Identities = 23/116 (19%), Positives = 43/116 (37%), Gaps = 10/116 (8%) Query: 133 TPERVDEFKYQMTRTNWHAT---EQYI-IEPEKIHELFPLLNMDKILAGLYNPGD-GHID 187 T E D ++ +A YI +E + F +N+ +L L P + Sbjct: 137 TKEDADRLMAELDAGAKNAVVIGGGYIGLEAAAVLTKF-GVNV-TLLEAL--PRVLARVA 192 Query: 188 PYSLTMALATGARKYGVLLKYPAPVTSLKPRPDGTWDVETPQGS-VRANRIVNAAG 242 +L+ R +GV L+ A + ++ V GS + A+ ++ G Sbjct: 193 GEALSEFYQAEHRAHGVDLRTGAAMDCIEGDGTKVTGVRMQDGSVIPADIVIVGIG 248 >5EQD-A nrPDB Length = 400 Score = 32.9 bits (73), Expect = 0.61, Method: Composition-based stats. Identities = 18/131 (13%), Positives = 44/131 (33%), Gaps = 11/131 (8%) Query: 42 RAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAG-------LTTYFHP 94 + ++G G G+++A A + V+++E+ G+ + H Sbjct: 4 NFDLFVVGSGFFGLTIAERAATQLGKRVLVIERRPHIGGNAYSEPEPETGIEVHKYGAHL 63 Query: 95 GINLKKIHYDSIKLYERLEEETGQVVGFHQPGSIRLATTPERVDEFKYQMTRTNWHATEQ 154 K +D ++ + +V H + + V +F + + E Sbjct: 64 FHTSNKRVWDYVRQFTDFTGYQHRVFAMHNGQAYQFPMGLGLVSQFFGRYFSPD----EA 119 Query: 155 YIIEPEKIHEL 165 + E+ E+ Sbjct: 120 RALIAEQASEI 130 >4X4J-A nrPDB Length = 507 Score = 32.9 bits (73), Expect = 0.62, Method: Composition-based stats. Identities = 42/219 (19%), Positives = 62/219 (28%), Gaps = 58/219 (26%) Query: 43 AETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKIH 102 A VI G G G+ LA L AG+ VVL G T Sbjct: 23 APVVIAGAGPAGLMLAGELRLAGIGVVVLERL--PARTGESRGLGFTARTME-------V 73 Query: 103 YDSIKLYERLEEETGQVVGFHQPGSIRLATTPERVDEFKYQMTRTNWHATEQYIIEPE-K 161 +D L R E G H G + +++ + Sbjct: 74 FDQRGLLRRFGEVQTSDQG-HFGGIP-----------------------VDFGLLDGAHQ 109 Query: 162 IHELFPLLNMDKILAGLYNPGDGHIDPYSLTMALATGARKYGVLLKYPAPVTSLKPRPDG 221 + P + +L A + G ++ +T ++ DG Sbjct: 110 AAKTIPQSATEAVLEAW--------------------AGELGADIRRGHELTGVRDDGDG 149 Query: 222 T-WDVETPQG--SVRANRIVNAAGFWAREVGKMIGLDHP 257 V P G +RA +V G V K +G D P Sbjct: 150 VAVTVRGPAGEHVLRAGWLVGCDGG-RSAVRKAVGFDFP 187 >4ZN0-A nrPDB Length = 311 Score = 32.9 bits (73), Expect = 0.65, Method: Composition-based stats. Identities = 11/37 (29%), Positives = 24/37 (64%), Gaps = 1/37 (2%) Query: 43 AETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTA 79 + +IIGGG G++ + + G+ D ++LE++E++ Sbjct: 8 YDLIIIGGGPAGLTAGIYAVRYGL-DTLILERNEISG 43 >1ZFN-A nrPDB Length = 253 Score = 32.9 bits (73), Expect = 0.65, Method: Composition-based stats. Identities = 12/42 (28%), Positives = 23/42 (54%) Query: 43 AETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWH 84 ++ +IIG G +G A +LA AG+ +VL + ++ + Sbjct: 31 SQVLIIGLGGLGTPAALYLAGAGVGTLVLADDDDVHLSNLQR 72 >1UXJ-A nrPDB Length = 309 Score = 32.9 bits (73), Expect = 0.69, Method: Composition-based stats. Identities = 14/32 (43%), Positives = 20/32 (62%) Query: 42 RAETVIIGGGCVGVSLAYHLAKAGMRDVVLLE 73 R + IIG G VG + A+ LA + D+VLL+ Sbjct: 2 RKKISIIGAGFVGSTTAHWLAAKELGDIVLLD 33 >2NVK-X nrPDB Length = 488 Score = 32.9 bits (73), Expect = 0.70, Method: Composition-based stats. Identities = 15/55 (27%), Positives = 23/55 (41%), Gaps = 1/55 (1%) Query: 35 SPPEWKDRAETVIIGGGCVGVSLAYHLAKAGMRDVVL-LEKSELTAGSTWHAAGL 88 +P + + ++IGGG G++ A G R L K T G+ W G Sbjct: 2 APVQGSYDYDLIVIGGGSAGLACAKEAVLNGARVACLDFVKPTPTLGTKWGVGGT 56 >3WSV-A nrPDB Length = 322 Score = 32.5 bits (72), Expect = 0.78, Method: Composition-based stats. Identities = 12/33 (36%), Positives = 20/33 (60%) Query: 40 KDRAETVIIGGGCVGVSLAYHLAKAGMRDVVLL 72 K + VI+G G VG S+AY + G+ + ++L Sbjct: 3 KTSRKVVIVGTGFVGTSIAYAMINQGVANELVL 35 >4NQW-A nrPDB Length = 204 Score = 32.5 bits (72), Expect = 0.82, Method: Composition-based stats. Identities = 15/86 (17%), Positives = 38/86 (44%), Gaps = 2/86 (2%) Query: 632 RVLQKLTSEDLSDDVFKFLQTKSLKISDIPVTAIR-ISYTGELGWELYHRREDSAALYER 690 +L+++ D + + TKS ++ + + +R Y+ E E+Y +A+ ++ Sbjct: 30 ALLRRVAGHDQAAFAEFYDHTKS-RVYGLVMRVLRDTGYSEETTQEIYLEVWRNASEFDS 88 Query: 691 IMNAGQEEGIDNFGTYALNALRLEKA 716 + + A++ +R E+A Sbjct: 89 AKGSALAWLLTMAHRRAVDRVRCEQA 114 >4IVM-B nrPDB Length = 483 Score = 32.5 bits (72), Expect = 0.82, Method: Composition-based stats. Identities = 26/150 (17%), Positives = 48/150 (32%), Gaps = 16/150 (10%) Query: 189 YSLTMALATGARKYGVLLKYPAPVTSLKPRPDGTWDVETPQGSVRANRIVNAAGFWAREV 248 L AL T GV + PV L + +G W V S+ A+ +++A + Sbjct: 240 EMLPQALETHLTSRGVSVLRGQPVCGLSLQAEGRWKVSLRDSSLEADHVISAIPA--SVL 297 Query: 249 GKMIGLDHPLIPVQHQYVVTSTIPEVKALKRELPVLRDLEGSYYLRQERDGLLFGPYESQ 308 +++ + + + + V+ +L + G L E Sbjct: 298 SELLPAEAAPLARALSAI----------TAVSVAVVNLQYQGAHLPVQGFGHLVPSSEDP 347 Query: 309 EKMKLQASWVA----HGVPPGFGKELFESD 334 + + VA G PPG + Sbjct: 348 GVLGIVYDSVAFPEQDGSPPGLRVTVMLGG 377 Score = 30.9 bits (68), Expect = 2.2, Method: Composition-based stats. Identities = 11/37 (29%), Positives = 21/37 (56%), Gaps = 2/37 (5%) Query: 45 TVIIGGGCVGVSLAYHLAKAGM--RDVVLLEKSELTA 79 V++GGG G++ +YHL++A + V++ L Sbjct: 11 VVVLGGGISGLAASYHLSRAPCPPKVVLVESSERLGG 47 >4NTC-A nrPDB Length = 335 Score = 32.5 bits (72), Expect = 0.87, Method: Composition-based stats. Identities = 13/62 (20%), Positives = 24/62 (38%), Gaps = 1/62 (1%) Query: 44 ETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKIHY 103 + +IIG G G+S A LA+ + V+ + T H + + H + Sbjct: 16 DVLIIGAGPAGLSTATGLARQ-LHTAVVFDSGVYRNAKTQHMHNVLGWDHRNPAELRAAG 74 Query: 104 DS 105 + Sbjct: 75 RA 76 >5Z70-A nrPDB Length = 605 Score = 32.1 bits (71), Expect = 0.95, Method: Composition-based stats. Identities = 15/79 (18%), Positives = 29/79 (36%), Gaps = 5/79 (6%) Query: 47 IIGGGCVGVSLAYHLAKAGM---RDVVLLEKSELTAGS--TWHAAGLTTYFHPGINLKKI 101 IIG G G++ A++L + G +D+ +L+ GS A G + Sbjct: 9 IIGSGIAGLASAFYLIRDGRMKGQDITILDAVGTPGGSLDGSGNAEDGYLIRGGREMNWN 68 Query: 102 HYDSIKLYERLEEETGQVV 120 + L++ + Sbjct: 69 YDHFWDLFQDIPALEYPSP 87 >6C6P-A nrPDB Length = 458 Score = 32.1 bits (71), Expect = 0.96, Method: Composition-based stats. Identities = 10/30 (33%), Positives = 18/30 (60%) Query: 44 ETVIIGGGCVGVSLAYHLAKAGMRDVVLLE 73 E +I+G G +G +LA L++ G + V+ Sbjct: 9 EVIIVGAGVLGSALAAVLSRDGRKVTVIER 38 >3Q6J-A nrPDB Length = 523 Score = 32.1 bits (71), Expect = 0.97, Method: Composition-based stats. Identities = 16/85 (18%), Positives = 33/85 (38%), Gaps = 1/85 (1%) Query: 41 DRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKK 100 + + IGGG G + +L G R +++ ++ GS H A + + + Sbjct: 42 REYDAIFIGGGAAGRFGSAYLRAMGGRQLIV-DRWPFLGGSCPHNACVPHHLFSDCAAEL 100 Query: 101 IHYDSIKLYERLEEETGQVVGFHQP 125 + + + T +VVG + Sbjct: 101 MLARTFSGQYWFPDMTEKVVGIKEV 125 >6QE4-A nrPDB Length = 327 Score = 32.1 bits (71), Expect = 0.99, Method: Composition-based stats. Identities = 50/309 (16%), Positives = 88/309 (28%), Gaps = 75/309 (24%) Query: 533 FNIKGQDSTQLLDHLCANVIPKVGFTN----------ISHMLTPRGRVYAELTVSHQSPG 582 ++G D+ L L N +P +H L +GR ++ + Sbjct: 30 LRVRGPDAAPFLLGLLTNELPLPSPAAAGAPPAARAGYAHFLNVQGRTLYDVILYGLQEH 89 Query: 583 E----FLLITGSGSELHDLRWIEEAAVRGGYDVEIRNITDELGVLGVAGPYARRVLQKLT 638 FLL S + + + +R VE EL V V Sbjct: 90 SEVSGFLLECDSSVQGALQKHLALYRIRRKVTVE---PHPELRVWAV------------- 133 Query: 639 SEDLSDDVFKFLQTKSLKISDIPVTAIRISYTGELGWEL--------YHRREDSAALYE- 689 L + + IR T +GW L L++ Sbjct: 134 ---LPSSPEACGAASLQERAGAAAILIRDPRTARMGWRLLTQDEGPALVPGGRLGDLWDY 190 Query: 690 --RIMNAGQEEGIDNFGTYALNALRLEKAFRAWGSEMNCDTNPLEAGLDYFIKLNKPADF 747 G EG+ + AL LE G+ + + Sbjct: 191 HQHRYLQGVPEGVRDLPPGV--ALPLESNLA------------FMNGVSFT-----KGCY 231 Query: 748 TGKQALKQIKAKGL-KRRLVCLT----LATDDVDPEGNESVWYKGKVIGNTTSGSYSYSI 802 G++ + G+ ++RL + L T + P G + G+ +G +G Sbjct: 232 IGQELTARTHHMGVIRKRLFPVRFLDPLPTSGITP-GATVLTASGQTVGKFRAG------ 284 Query: 803 QKSLAFAYV 811 Q ++ A + Sbjct: 285 QGNVGLALL 293 >4YNU-A nrPDB Length = 571 Score = 32.1 bits (71), Expect = 1.0, Method: Composition-based stats. Identities = 10/34 (29%), Positives = 19/34 (55%) Query: 42 RAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKS 75 + +++GGG G+ +A L++ V+LLE Sbjct: 5 TYDYIVVGGGTSGLVVANRLSENPDVSVLLLEAG 38 >3LZX-A nrPDB Length = 332 Score = 32.1 bits (71), Expect = 1.0, Method: Composition-based stats. Identities = 21/110 (19%), Positives = 35/110 (31%), Gaps = 16/110 (14%) Query: 38 EWKDRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAGLTTYFHPGIN 97 E + IIGGG VG+ A++ ++ +L + Y G Sbjct: 3 EDTKVYDITIIGGGPVGLFTAFYGGMRQASVKIIESLPQLGGQLSALYPEKYIYDVAGFP 62 Query: 98 LKKIHYDSIKLYERLEEET---GQVVGFHQP---------GSIRLATTPE 135 + +L L+E+ Q + Q G +L T E Sbjct: 63 KI----RAQELINNLKEQMAKFDQTICLEQAVESVEKQADGVFKLVTNEE 108 >4F5M-A nrPDB Length = 406 Score = 32.1 bits (71), Expect = 1.1, Method: Composition-based stats. Identities = 25/111 (22%), Positives = 39/111 (35%), Gaps = 7/111 (6%) Query: 49 GGGCVGVSLAYHLAKA-GMRDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKIHYDSIK 107 GG A LAK ++ V + S S +++AGL + + + D Sbjct: 112 GGTGALRVAADFLAKNTSVKRVWVSNPSWPNHKSVFNSAGLEVREYAYYDAENHTLDFDA 171 Query: 108 LYERLEE-ETGQVVGFHQPGSIRLATTPERVDEFKYQMTRTNWHATEQYII 157 L L E + G VV FH P +D Q + E+ + Sbjct: 172 LINSLNEAQAGDVVLFH-----GCCHNPTGIDPTLEQWQTLAQLSVEKGWL 217 >2ZBW-A nrPDB Length = 335 Score = 32.1 bits (71), Expect = 1.2, Method: Composition-based stats. Identities = 19/106 (17%), Positives = 33/106 (31%), Gaps = 6/106 (5%) Query: 41 DRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKK 100 D + +I+G G G+ +++ G+ + E T Y G Sbjct: 4 DHTDVLIVGAGPTGLFAGFYVGMRGLSFRFVDPLPEPGGQLTALYPEKYIYDVAGFPKV- 62 Query: 101 IHYDSIKLYERLEEETGQVVGFHQPGSIRLATTPERVDEFKYQMTR 146 + L + L E+ + G A T ER + T Sbjct: 63 ---YAKDLVKGLVEQVAPFNPVYSLG--ERAETLEREGDLFKVTTS 103 >1I8T-A nrPDB Length = 367 Score = 31.7 bits (70), Expect = 1.3, Method: Composition-based stats. Identities = 8/38 (21%), Positives = 18/38 (47%) Query: 43 AETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAG 80 + +I+G G G A L K + +V+ +++ + Sbjct: 2 YDYIIVGSGLFGAVCANELKKLNKKVLVIEKRNHIGGN 39 >4MO2-B nrPDB Length = 368 Score = 31.7 bits (70), Expect = 1.3, Method: Composition-based stats. Identities = 8/38 (21%), Positives = 17/38 (44%) Query: 43 AETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAG 80 + +I+G G G AY + G +V+ ++ + Sbjct: 2 YDYLIVGSGLFGSIFAYEATEKGYTCLVVEQREHIGGN 39 >6GAS-A nrPDB Length = 331 Score = 31.7 bits (70), Expect = 1.3, Method: Composition-based stats. Identities = 14/79 (17%), Positives = 28/79 (35%), Gaps = 4/79 (5%) Query: 37 PEWKDRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAGLTTYFHPGI 96 E + + IIGGG G+ A++ ++ +L + Y G Sbjct: 4 AENQKVYDITIIGGGPTGLFTAFYGGMRQASVKIIESLPQLGGQLSALYPEKYIYDVAGF 63 Query: 97 NLKKIHYDSIKLYERLEEE 115 + +L + L+E+ Sbjct: 64 PKV----RAQELVDNLKEQ 78 >1MAF-H nrPDB Length = 373 Score = 31.7 bits (70), Expect = 1.4, Method: Composition-based stats. Identities = 17/98 (17%), Positives = 26/98 (26%), Gaps = 3/98 (3%) Query: 362 NGPITYSPDILPMV---GPHQGVRNYWVAIGFGYGIIHAGGVGKYLSDWILHGEPPFDLI 418 N + + H + WV I+ G + H F L Sbjct: 24 NDEAPGADGRRSYINLPAHHSAIIQQWVLDAGSGSILGHVNGGFLPNPVAAHSGSEFALA 83 Query: 419 ELDPNRYGKWTTTQYTEAKARESYGFNNIVGYPKEERF 456 +R K T Y E ++ + P RF Sbjct: 84 STSFSRIAKGKRTDYVEVFDPVTFLPIADIELPDAPRF 121 >3RED-A nrPDB Length = 521 Score = 31.7 bits (70), Expect = 1.5, Method: Composition-based stats. Identities = 14/42 (33%), Positives = 22/42 (52%), Gaps = 2/42 (4%) Query: 38 EWKDRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTA 79 E + + VI+GGG G LA L++ V++LE+ L Sbjct: 22 ELEGSYDYVIVGGGTSGCPLAATLSEK--YKVLVLERGTLPT 61 >5BR7-A nrPDB Length = 393 Score = 31.7 bits (70), Expect = 1.6, Method: Composition-based stats. Identities = 15/109 (13%), Positives = 43/109 (39%), Gaps = 7/109 (6%) Query: 43 AETVIIGGGCVGVSLAYHLAKA-GMRDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKI 101 + +++G G G+++A A G + +++ ++S L + A T Sbjct: 4 FDLIVVGSGLFGLTVAERAASQLGKKVLIVEKRSHLGGNAYSEAEPETGIEIHKYGAHLF 63 Query: 102 HYDSIKLYERLEEET------GQVVGFHQPGSIRLATTPERVDEFKYQM 144 H + ++++ + + T +V H + + +++F + Sbjct: 64 HTSNKRVWDYVNQFTAFTGYQHRVFAMHNGTAYQFPMGLGLINQFFGRY 112 >1DOD-A nrPDB Length = 394 Score = 31.3 bits (69), Expect = 1.7, Method: Composition-based stats. Identities = 12/35 (34%), Positives = 20/35 (57%) Query: 42 RAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSE 76 + + IIG G G+ L L KAG+ +V+L ++ Sbjct: 2 KTQVAIIGAGPSGLLLGQLLHKAGIDNVILERQTP 36 >2D3L-A nrPDB Length = 485 Score = 31.3 bits (69), Expect = 1.7, Method: Composition-based stats. Identities = 19/109 (17%), Positives = 31/109 (28%), Gaps = 9/109 (8%) Query: 470 ILESKCSMGFHAGWEQP----HWFYKPGQDTQYRPSFRRTNWFRPVGSEYKQVMQRVGVI 525 + +M + W P HW + + W P Q G Sbjct: 2 HNGTNGTMMQYFEWYLPNDGNHWNRLNSDASNLKSKGITAVWIPPAWKGASQNDVGYGAY 61 Query: 526 DLSPFGKFNIKGQDSTQL-----LDHLCANVIPKVGFTNISHMLTPRGR 569 DL G+FN KG T+ L ++ ++ +G Sbjct: 62 DLYDLGEFNQKGTVRTKYGTRSQLQAAVTSLKNNGIQVYGDVVMNHKGG 110 >1ZDL-A nrPDB Length = 517 Score = 31.3 bits (69), Expect = 1.8, Method: Composition-based stats. Identities = 12/49 (24%), Positives = 21/49 (42%) Query: 40 KDRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAGL 88 + + ++IGGG G++ A A+ G + V G+ W G Sbjct: 30 QQSFDLLVIGGGSGGLACAKEAAQLGKKVAVADYVEPSPRGTKWGLGGT 78 >2HQM-A nrPDB Length = 479 Score = 31.3 bits (69), Expect = 1.8, Method: Composition-based stats. Identities = 40/214 (18%), Positives = 72/214 (33%), Gaps = 25/214 (11%) Query: 41 DRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAG--STWHAAGLTTYFHPGINL 98 + ++IGGG GV+ A A G + +++ K+ L + ++ + Sbjct: 10 KHYDYLVIGGGSGGVASARRAASYGAKTLLVEAKA-LGGTCVNVGCVPKKVMWYASDLAT 68 Query: 99 KKIHYDSIKLYERLEEETGQVVGFHQPGSIRLATTPERVDEFKYQMTR--TNWHATEQYI 156 + H + LY+ L + + F+ P EFK + + Q Sbjct: 69 RVSHANEYGLYQNLPLDKEHLT-FNWP-------------EFKQKRDAYVHRLNGIYQKN 114 Query: 157 IEPEKIHELFPLLNMDKILAGLYNPGDGHIDPYSLTMALATGARKYGVLLKYPAPVTSLK 216 +E EK+ +F +K D + YS L A + P L Sbjct: 115 LEKEKVDVVFGWARFNKDGNVEVQKRDNTTEVYSANHILV--ATGGKAIFPENIPGFELG 172 Query: 217 PRPDGTWDVETPQGSVRANRIVNAAGFWAREVGK 250 DG + +E +V AG+ E+ Sbjct: 173 TDSDGFFRLEEQ----PKKVVVVGAGYIGIELAG 202 >4UDQ-A nrPDB Length = 531 Score = 31.3 bits (69), Expect = 1.9, Method: Composition-based stats. Identities = 12/33 (36%), Positives = 17/33 (51%) Query: 43 AETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKS 75 + VI+GGG G LA L+ V+L+E Sbjct: 6 FDYVIVGGGTAGSVLANRLSARPENRVLLIEAG 38 >4AP1-A nrPDB Length = 549 Score = 31.3 bits (69), Expect = 1.9, Method: Composition-based stats. Identities = 16/112 (14%), Positives = 33/112 (29%), Gaps = 7/112 (6%) Query: 34 PSPPEWKDRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAGLTTYFH 93 P + V++G G G+ + G+ S + W+ Y Sbjct: 13 PDATTGTTSYDVVVVGAGIAGLYAIHRFRSQGLTVRAFEAASGVGGVWYWN-----RYPG 67 Query: 94 PGINLKKIHYDSIKLYERLEEETGQVVGF-HQPGSIRLATTPERVDEFKYQM 144 +++ I S LE+E + QP + + + + Sbjct: 68 ARCDVESI-DYSYSFSPELEQEWNWSEKYATQPEILAYLEHVADRFDLRRDI 118 >1CSN-A nrPDB Length = 298 Score = 31.3 bits (69), Expect = 2.0, Method: Composition-based stats. Identities = 9/37 (24%), Positives = 21/37 (56%) Query: 37 PEWKDRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLE 73 P+ +D T + GC G+ Y+ + G+ +V++++ Sbjct: 50 PQLRDEYRTYKLLAGCTGIPNVYYFGQEGLHNVLVID 86 >3RP7-A nrPDB Length = 407 Score = 30.9 bits (68), Expect = 2.2, Method: Composition-based stats. Identities = 40/257 (15%), Positives = 68/257 (26%), Gaps = 25/257 (9%) Query: 211 PVTSLKPRPDGTWDVETPQGSVRANRIVNAAGFWAREVGKMIGLDHPLIPVQHQYVVTS- 269 VT + DG T S + ++ A G + ++G P Sbjct: 147 RVTRCEEDADGVTVWFTDGSSASGDLLIAADGSHSALRPWVLGFT-PQRRYAGYVNWNGL 205 Query: 270 -TIPEVKALKRELPVLRDLEGSYYLRQERDGLLF---------GPYESQEKMKLQASWVA 319 I E A + L G + G E ++ ++ S Sbjct: 206 VEIDEALAPGDQWTTFVGEGKRVSLMPVSAGRFYFFFDVPLPAGLAEDRDTLRADLSRYF 265 Query: 320 HGVPPGFGKELFESDLDRITEHVEAAMEMVPVLKKADIINIVNGPITYSPDILPMVGPHQ 379 G P K + D +E L + + + + + +PDI G Sbjct: 266 AGWAPPVQKLIAALDPQTTNRIEIHDIEPFSRLVRGRVALLGDAGHSTTPDIGQG-GCAA 324 Query: 380 GVRNYWVAIGFGYGIIHAGGVGKYLS-------DWILHGEPPFDLIELDPNRYGKWTTTQ 432 + F A + +Y + D +L D T+ Sbjct: 325 MEDAVVLGAVFRQTRDIAAALREYEAQRCDRVRDLVLKAR-----KRCDITHGKDMQLTE 379 Query: 433 YTEAKARESYGFNNIVG 449 + RE G I G Sbjct: 380 AWYQELREETGERIING 396 >3GDN-A nrPDB Length = 521 Score = 30.9 bits (68), Expect = 2.3, Method: Composition-based stats. Identities = 14/42 (33%), Positives = 22/42 (52%), Gaps = 2/42 (4%) Query: 38 EWKDRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTA 79 E + + VI+GGG G LA L++ V++LE+ L Sbjct: 22 ELEGSYDYVIVGGGTSGCPLAATLSEK--YKVLVLERGSLPT 61 >2X3N-A nrPDB Length = 399 Score = 30.9 bits (68), Expect = 2.3, Method: Composition-based stats. Identities = 46/286 (16%), Positives = 84/286 (29%), Gaps = 55/286 (19%) Query: 44 ETVIIGGGCVGVSLAYHLAKAGMRDVVLL---EKSELTAGSTWHAAGLTTYFHPGINLKK 100 + +I G G G LAY L + G R VV+ + + AG+ G+ L + Sbjct: 8 DVLINGCGIGGAMLAYLLGRQGHRVVVVEQARRERAINGADLLKPAGIRVVEAAGL-LAE 66 Query: 101 IHYDSIKLYERLEEETGQVVGFHQPGSIRLATTPERVDEFKYQMTRTNWHATEQYIIEPE 160 + ++ L E E ++ A +I+ P Sbjct: 67 VTRRGGRVRHEL--EVYHD------------------GELLRYFNYSSVDARGYFILMP- 105 Query: 161 KIHELFPLLNMDKILAGLYNPGDGHIDPYSLTMALATGARKYGVLLKYPAPVTSLKPRPD 220 E L ++KI + V + + + +++ Sbjct: 106 --CESLRRLVLEKIDG------------------------EATVEMLFETRIEAVQRDER 139 Query: 221 GTWD-VETPQGSVRANRIVNAAGFWAREV-GKMIGLDHPLIPVQHQYVVTSTIPEVKALK 278 D V G V R+V A A V +++ +D P +V + + Sbjct: 140 HAIDQVRLNDGRVLRPRVVVGADGIASYVRRRLLDIDVERRPYPSPMLVGTFALAPCVAE 199 Query: 279 RELPVLRDLEGSYYLRQER--DGLLFGPYESQEKMKLQASWVAHGV 322 R + G Y L + +E +L A + Sbjct: 200 RNRLYVDSQGGLAYFYPIGFDRARLVVSFPREEARELMADTRGESL 245 >3B40-A nrPDB Length = 417 Score = 30.2 bits (66), Expect = 3.8, Method: Composition-based stats. Identities = 23/151 (15%), Positives = 53/151 (35%), Gaps = 16/151 (10%) Query: 60 HLAKAGMRDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKIHYDSIKLYERLEEETGQV 119 ++ + V L ++ + A + A + + + ++ DS + QV Sbjct: 213 QMSTKALEQVAALSRAPIVASHSAPRALVDIKRNLSDHEMQLIKDSGGVI--------QV 264 Query: 120 VGFHQPGSIRLATTPERVDEFKYQMTRTNWHATEQYIIEPEKIHELFPLLNMDKILAGLY 179 VGF T +++D + + + ++ + I ++P + + LY Sbjct: 265 VGFPAYLRPLSKPTLDKLDALRARFDLPPLEGLDYALMPGDPIITIWPEQRFGEYASALY 324 Query: 180 -----NPGDGHIDPYSLTMALATGARKYGVL 205 P G + L A+ +K G+ Sbjct: 325 GILEEEPKAGLKE---LVDAIDYTVKKVGID 352 >4HA6-A nrPDB Length = 508 Score = 30.2 bits (66), Expect = 4.0, Method: Composition-based stats. Identities = 35/213 (16%), Positives = 60/213 (28%), Gaps = 28/213 (13%) Query: 44 ETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAG----STWHAAGLTTYFHPG--IN 97 + VI+GGG G LA L++ V+L+E E + L + Sbjct: 3 DIVIVGGGSAGSLLAARLSEDPDSRVLLIEAGEEPTDPDIWNPAAWPALQGRSYDWDYRT 62 Query: 98 LKKIHYDSIKLYERLEEETGQVVGFHQPGSIRLATTPERVDEFKYQMTRT--NWHATEQY 155 + + G H G +R +F+ + + + Sbjct: 63 EAQAGTAGRAHHWARGRLIGGSSCLHAMGYMR-----GHPSDFQAWVDASGDRRWGWD-E 116 Query: 156 IIEPEKIHELFPLLNMDKILAG----LYNPGDGHIDPYSLTMALATGARKYGVLLKYPAP 211 ++ + E PL G ++ P D + L A G+ Sbjct: 117 LLPVFQAIEDHPLGGDGIHGKGGPLPIHLPAD---EVSPLARAFIEAGASLGLPRLE--- 170 Query: 212 VTSLKPRPDGTWDVETPQGSVRANRIVNAAGFW 244 V ++R R V AA W Sbjct: 171 ----GHNSGEMIGVTPNSLNIRDGRRVTAADAW 199 >2EPJ-A nrPDB Length = 434 Score = 29.4 bits (64), Expect = 7.5, Method: Composition-based stats. Identities = 40/223 (17%), Positives = 70/223 (31%), Gaps = 30/223 (13%) Query: 171 MDKILAGLYNP---GDGHIDPYS-LTMALATGARKYGVLLKYPAPVTSLKPRPDGTWDVE 226 D+I + P G I P AL +R+ G LL VT + +G Sbjct: 201 GDRIAGVIVEPVIANAGVIPPRREFLAALQRLSRESGALLILDEVVTGFRLGLEGAQGYF 260 Query: 227 TPQGSVRANRIVNAAGFWAREVGKMIGLDHPLIPVQHQYVVTSTIPEVKALKRELPVLRD 286 +G + +GK+IG P+ V V S + + V Sbjct: 261 NIEGDII-------------VLGKIIGGGFPVGAVAGSREVMSLLTP------QGKVFNA 301 Query: 287 LEGSYYLRQERDGLLFGPYESQEKMKLQASWVAHGVPPGFGKELFESDLDRITEHVEAAM 346 + + GL +E + + A + + L + L VE+ M Sbjct: 302 GTFNAHPITMAAGLATLKALEEEPVYSVSREAAKALEEAASEVLDRTGLPYTINRVESMM 361 Query: 347 EMVPVLKKADIINIVNGPITYSPDILPMVGPHQG--VRNYWVA 387 ++ +++ N D V H+ R ++A Sbjct: 362 QLFIGVEEVS-----NAAQARKADKKFYVKLHEEMLRRGVFIA 399 >6AH0-2 nrPDB Length = 895 Score = 29.0 bits (63), Expect = 8.2, Method: Composition-based stats. Identities = 11/28 (39%), Positives = 16/28 (57%), Gaps = 1/28 (3%) Query: 460 PTQRVSGLYKILESKCSMGFHA-GWEQP 486 P ++ GL + CS G+HA GW +P Sbjct: 646 PNLKIPGLNSPIPESCSFGYHAGGWGKP 673 >5W1J-A nrPDB Length = 584 Score = 29.0 bits (63), Expect = 8.5, Method: Composition-based stats. Identities = 19/51 (37%), Positives = 26/51 (50%) Query: 38 EWKDRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWHAAGL 88 E K + VIIGGG G++LA AK+G + +L G+TW G Sbjct: 99 EMKYDYDMVIIGGGSGGLALAKESAKSGAKVALLDFVVPTPMGTTWGLGGT 149 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.306 0.122 0.292 Lambda K H 0.267 0.0373 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 28,633,269 Number of Sequences: 36641 Number of extensions: 1157358 Number of successful extensions: 3820 Number of sequences better than 10.0: 184 Number of HSP's better than 10.0 without gapping: 173 Number of HSP's successfully gapped in prelim test: 85 Number of HSP's that attempted gapping in prelim test: 3424 Number of HSP's gapped (non-prelim): 310 length of query: 857 length of database: 10,336,785 effective HSP length: 105 effective length of query: 752 effective length of database: 6,489,480 effective search space: 4880088960 effective search space used: 4880088960 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 63 (29.0 bits)