BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q61143 (930 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 6CV9-A nrPDB 1734 0.0 6CUD-A nrPDB 1256 0.0 6G1K-A nrPDB 541 e-154 6DJS-A nrPDB 524 e-149 5Z96-A nrPDB 518 e-147 6BWF-A nrPDB 58 2e-08 5AQA-A nrPDB 56 6e-08 5MKE-A nrPDB 55 1e-07 5AQ9-A nrPDB 54 3e-07 5MIO-C nrPDB 52 1e-06 5T4D-A nrPDB 51 2e-06 6D1W-A nrPDB 51 2e-06 5H76-A nrPDB 50 6e-06 5AQ7-A nrPDB 47 3e-05 6MWQ-A nrPDB 46 7e-05 6DU8-A nrPDB 46 1e-04 6FES-A nrPDB 45 1e-04 6MHW-A nrPDB 45 1e-04 5AQB-A nrPDB 45 1e-04 5Z1W-A nrPDB 43 6e-04 6DVZ-A nrPDB 42 0.001 4OAU-C nrPDB 42 0.001 5CBO-A nrPDB 40 0.004 6BPQ-A nrPDB 40 0.004 5IRX-A nrPDB 40 0.005 5GP7-A nrPDB 38 0.026 6BBJ-A nrPDB 36 0.082 6BOA-A nrPDB 35 0.16 4Z68-A nrPDB 35 0.19 6C8G-A nrPDB 35 0.21 6BWI-A nrPDB 35 0.22 6BY9-A nrPDB 34 0.25 6E2G-A nrPDB 34 0.34 6DMR-A nrPDB 34 0.36 3B7B-A nrPDB 33 0.61 5HKP-A nrPDB 32 0.94 5JHQ-A nrPDB 32 1.2 4O1O-A nrPDB 32 1.4 1BD8-A nrPDB 31 2.2 1G3N-B nrPDB 31 2.4 1WG0-A nrPDB 31 2.6 1OED-B nrPDB 30 4.2 4BOT-B nrPDB 29 8.3 >6CV9-A nrPDB Length = 842 Score = 1734 bits (4492), Expect = 0.0, Method: Compositional matrix adjust. Identities = 837/837 (100%), Positives = 837/837 (100%) Query: 94 LSIEEERFLDAAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLAVANEHLEITELLLK 153 LSIEEERFLDAAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLAVANEHLEITELLLK Sbjct: 6 LSIEEERFLDAAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLAVANEHLEITELLLK 65 Query: 154 KENLSRVGDALLLAISKGYVRIVEAILNHPAFAEGKRLATSPSQSELQQDDFYAYDEDGT 213 KENLSRVGDALLLAISKGYVRIVEAILNHPAFAEGKRLATSPSQSELQQDDFYAYDEDGT Sbjct: 66 KENLSRVGDALLLAISKGYVRIVEAILNHPAFAEGKRLATSPSQSELQQDDFYAYDEDGT 125 Query: 214 RFSHDVTPIILAAHCQEYEIVHTLLRKGARIERPHDYFCKCTECSQKQKHDSFSHSRSRI 273 RFSHDVTPIILAAHCQEYEIVHTLLRKGARIERPHDYFCKCTECSQKQKHDSFSHSRSRI Sbjct: 126 RFSHDVTPIILAAHCQEYEIVHTLLRKGARIERPHDYFCKCTECSQKQKHDSFSHSRSRI 185 Query: 274 NAYKGLASPAYLSLSSEDPVMTALELSNELAVLANIEKEFKNDYRKLSMQCKDFVVGLLD 333 NAYKGLASPAYLSLSSEDPVMTALELSNELAVLANIEKEFKNDYRKLSMQCKDFVVGLLD Sbjct: 186 NAYKGLASPAYLSLSSEDPVMTALELSNELAVLANIEKEFKNDYRKLSMQCKDFVVGLLD 245 Query: 334 LCRNTEEVEAILNGDAETRQPGDFGRPNLSRLKLAIKYEVKKFVAHPNCQQQLLSIWYEN 393 LCRNTEEVEAILNGDAETRQPGDFGRPNLSRLKLAIKYEVKKFVAHPNCQQQLLSIWYEN Sbjct: 246 LCRNTEEVEAILNGDAETRQPGDFGRPNLSRLKLAIKYEVKKFVAHPNCQQQLLSIWYEN 305 Query: 394 LSGLRQQTMAVKFLVVLAVAIGLPFLALIYWCAPCSKMGKILRGPFMKFVAHAASFTIFL 453 LSGLRQQTMAVKFLVVLAVAIGLPFLALIYWCAPCSKMGKILRGPFMKFVAHAASFTIFL Sbjct: 306 LSGLRQQTMAVKFLVVLAVAIGLPFLALIYWCAPCSKMGKILRGPFMKFVAHAASFTIFL 365 Query: 454 GLLVMNAADRFEGTKLLPNETSTDNARQLFRMKTSCFSWMEMLIISWVIGMIWAECKEIW 513 GLLVMNAADRFEGTKLLPNETSTDNARQLFRMKTSCFSWMEMLIISWVIGMIWAECKEIW Sbjct: 366 GLLVMNAADRFEGTKLLPNETSTDNARQLFRMKTSCFSWMEMLIISWVIGMIWAECKEIW 425 Query: 514 TQGPKEYLFELWNMLDFGMLAIFAASFIARFMAFWHASKAQSIIDANDTLKDLTKVTLGD 573 TQGPKEYLFELWNMLDFGMLAIFAASFIARFMAFWHASKAQSIIDANDTLKDLTKVTLGD Sbjct: 426 TQGPKEYLFELWNMLDFGMLAIFAASFIARFMAFWHASKAQSIIDANDTLKDLTKVTLGD 485 Query: 574 NVKYYNLARIKWDPTDPQIISEGLYAIAVVLSFSRIAYILPANESFGPLQISLGRTVKDI 633 NVKYYNLARIKWDPTDPQIISEGLYAIAVVLSFSRIAYILPANESFGPLQISLGRTVKDI Sbjct: 486 NVKYYNLARIKWDPTDPQIISEGLYAIAVVLSFSRIAYILPANESFGPLQISLGRTVKDI 545 Query: 634 FKFMVIFIMVFVAFMIGMFNLYSYYIGAKQNEAFTTVEESFKTLFWAIFGLSEVKSVVIN 693 FKFMVIFIMVFVAFMIGMFNLYSYYIGAKQNEAFTTVEESFKTLFWAIFGLSEVKSVVIN Sbjct: 546 FKFMVIFIMVFVAFMIGMFNLYSYYIGAKQNEAFTTVEESFKTLFWAIFGLSEVKSVVIN 605 Query: 694 YNHKFIENIGYVLYGVYNVTMVIVLLNMLIAMINSSFQEIEDDADVEWKFARAKLWFSYF 753 YNHKFIENIGYVLYGVYNVTMVIVLLNMLIAMINSSFQEIEDDADVEWKFARAKLWFSYF Sbjct: 606 YNHKFIENIGYVLYGVYNVTMVIVLLNMLIAMINSSFQEIEDDADVEWKFARAKLWFSYF 665 Query: 754 EEGRTLPVPFNLVPSPKSLLYLLLKFKKWMCELIQGQKQGFQEDAEMNKRNEEKKFGISG 813 EEGRTLPVPFNLVPSPKSLLYLLLKFKKWMCELIQGQKQGFQEDAEMNKRNEEKKFGISG Sbjct: 666 EEGRTLPVPFNLVPSPKSLLYLLLKFKKWMCELIQGQKQGFQEDAEMNKRNEEKKFGISG 725 Query: 814 SHEDLSKFSLDKNQLAHNKQSSTRSSEDYHLNSFSNPPRQYQKIMKRLIKRYVLQAQIDK 873 SHEDLSKFSLDKNQLAHNKQSSTRSSEDYHLNSFSNPPRQYQKIMKRLIKRYVLQAQIDK Sbjct: 726 SHEDLSKFSLDKNQLAHNKQSSTRSSEDYHLNSFSNPPRQYQKIMKRLIKRYVLQAQIDK 785 Query: 874 ESDEVNEGELKEIKQDISSLRYELLEEKSQNTEDLAELIRKLGERLSLEPKLEESRR 930 ESDEVNEGELKEIKQDISSLRYELLEEKSQNTEDLAELIRKLGERLSLEPKLEESRR Sbjct: 786 ESDEVNEGELKEIKQDISSLRYELLEEKSQNTEDLAELIRKLGERLSLEPKLEESRR 842 >6CUD-A nrPDB Length = 806 Score = 1256 bits (3249), Expect = 0.0, Method: Compositional matrix adjust. Identities = 612/829 (73%), Positives = 706/829 (85%), Gaps = 25/829 (3%) Query: 71 LREKGRRLANRGPAYMFNDHSTSLSIEEERFLDAAEYGNIPVVRKMLEECHSLNVNCVDY 130 +REKGRR A RGPA+MFND TSL+ EEERFLDAAEYGNIPVVRKMLEE +LNVNCVDY Sbjct: 1 MREKGRRQAVRGPAFMFNDRGTSLTAEEERFLDAAEYGNIPVVRKMLEESKTLNVNCVDY 60 Query: 131 MGQNALQLAVANEHLEITELLLKKENLSRVGDALLLAISKGYVRIVEAILNHPAFAEGKR 190 MGQNALQLAV NEHLE+TELLLKKENL+R+GDALLLAISKGYVRIVEAILNHP FA KR Sbjct: 61 MGQNALQLAVGNEHLEVTELLLKKENLARIGDALLLAISKGYVRIVEAILNHPGFAASKR 120 Query: 191 LATSPSQSELQQDDFYAYDEDGTRFSHDVTPIILAAHCQEYEIVHTLLRKGARIERPHDY 250 L SP + ELQ DDFYAYDEDGTRFS D+TPIILAAHCQ+YE+VH LL KGARIERPHDY Sbjct: 121 LTLSPCEQELQDDDFYAYDEDGTRFSPDITPIILAAHCQKYEVVHMLLMKGARIERPHDY 180 Query: 251 FCKCTECSQKQKHDSFSHSRSRINAYKGLASPAYLSLSSEDPVMTALELSNELAVLANIE 310 FCKC +C +KQ+HDSFSHSRSRINAYKGLASPAYLSLSSEDPV+TALELSNELA LANIE Sbjct: 181 FCKCGDCMEKQRHDSFSHSRSRINAYKGLASPAYLSLSSEDPVLTALELSNELAKLANIE 240 Query: 311 KEFKNDYRKLSMQCKDFVVGLLDLCRNTEEVEAILNGDAETRQPGDFGR--PNLSRLKLA 368 KEFKNDYRKLSMQCKDFVVG+LDLCR++EEVEAILNGD E+ +P + R +LSR+KLA Sbjct: 241 KEFKNDYRKLSMQCKDFVVGVLDLCRDSEEVEAILNGDLESAEPLEVHRHKASLSRVKLA 300 Query: 369 IKYEVKKFVAHPNCQQQLLSIWYENLSGLRQQTMAVKFLVVLAVAIGLPFLALIYWCAPC 428 IKYEVKKFVAHPNCQQQLL+IWYENLSGLR+QT+A+K LVVL VA+GLPFLA+ YW APC Sbjct: 301 IKYEVKKFVAHPNCQQQLLTIWYENLSGLREQTIAIKCLVVLVVALGLPFLAIGYWIAPC 360 Query: 429 SKMGKILRGPFMKFVAHAASFTIFLGLLVMNAADRFEGTKLLPNETSTDNARQLFRMKTS 488 S++GKILR PFMKFVAHAASF IFLGLLV NA+DRFEG LPN T TD +Q+FR+KT+ Sbjct: 361 SRLGKILRSPFMKFVAHAASFIIFLGLLVFNASDRFEGITTLPNITVTDYPKQIFRVKTT 420 Query: 489 CFSWMEMLIISWVIGMIWAECKEIWTQGPKEYLFELWNMLDFGMLAIFAASFIARFMAFW 548 F+W EMLI+ WV+GM+W+ECKE+W +GP+EY+ +LWN+LDFGML+IF A+F ARF+AF Sbjct: 421 QFTWTEMLIMVWVLGMMWSECKELWLEGPREYILQLWNVLDFGMLSIFIAAFTARFLAFL 480 Query: 549 HASKAQSIIDANDTLKDLTKVTLGDNVKYYNLARIKWDPTDPQIISEGLYAIAVVLSFSR 608 A+KAQ +D+ DL++VTL ++Y+ AR KW P+DPQIISEGLYAIAVVLSFSR Sbjct: 481 QATKAQQYVDSYVQESDLSEVTLPPEIQYFTYARDKWLPSDPQIISEGLYAIAVVLSFSR 540 Query: 609 IAYILPANESFGPLQISLGRTVKDIFKFMVIFIMVFVAFMIGMFNLYSYYIGAKQNEAFT 668 IAYILPANESFGPLQISLGRTVKDIFKFMV+FIMVF AFMIGMF LYSYY+GAK N AFT Sbjct: 541 IAYILPANESFGPLQISLGRTVKDIFKFMVLFIMVFFAFMIGMFILYSYYLGAKVNAAFT 600 Query: 669 TVEESFKTLFWAIFGLSEVKSVVINYNHKFIENIGYVLYGVYNVTMVIVLLNMLIAMINS 728 TVEESFKTLFW+IFGLSEV SVV+ Y+HKFIENIGYVLYG+YNVTMV+VLLNMLIAMINS Sbjct: 601 TVEESFKTLFWSIFGLSEVTSVVLKYDHKFIENIGYVLYGIYNVTMVVVLLNMLIAMINS 660 Query: 729 SFQEIEDDADVEWKFARAKLWFSYFEEGRTLPVPFNLVPSPKSLLYLLLKFKKWMCELIQ 788 S+QEIEDD+DVEWKFAR+KLW SYF++G+TLP PF+LVPSPKS +Y +++ + + Sbjct: 661 SYQEIEDDSDVEWKFARSKLWLSYFDDGKTLPPPFSLVPSPKSFVYFIMR----IVNFPK 716 Query: 789 GQKQGFQEDAEMNKRNEEKKFGISGSHEDLSKFSLDKNQLAHNKQSSTRSSEDYHLNSFS 848 +++ Q+D EM G+ S L+ F+ QS++R E + NS Sbjct: 717 CRRRRLQKDIEM---------GMGNSKSRLNLFT----------QSNSRVFESHSFNSIL 757 Query: 849 NPPRQYQKIMKRLIKRYVLQAQIDKESDEVNEGELKEIKQDISSLRYEL 897 N P +YQ+IMKRLIKRYVL+AQ+DKE+DEVNEGELKEIKQDISSLRYEL Sbjct: 758 NQPTRYQQIMKRLIKRYVLKAQVDKENDEVNEGELKEIKQDISSLRYEL 806 >6G1K-A nrPDB Length = 921 Score = 541 bits (1394), Expect = e-154, Method: Compositional matrix adjust. Identities = 322/830 (38%), Positives = 459/830 (55%), Gaps = 129/830 (15%) Query: 92 TSLSIEEERFLDAAEYGNIPVVRKMLEECH---SLNVNCVDYMGQNALQLAVANEHLEIT 148 + LS +E+ +L A E G+ V+ LEE +N+NC+D +G+ AL +A+ NE+LEI Sbjct: 27 SELSTQEKSYLSAVEKGDYASVKLALEEAEIYFKININCIDPLGRTALLIAIENENLEII 86 Query: 149 ELLLKKENLSRVGDALLLAISKGYVRIVEAILNHPAFAEGKRLATSPSQSELQQDDFYAY 208 ELLL VGDALL AI K V VE +LNH + K++ Sbjct: 87 ELLLSFN--VYVGDALLHAIRKEVVGAVELLLNHKKPSGEKQVPP------------ILL 132 Query: 209 DEDGTRFSHDVTPIILAAHCQEYEIVHTLLRKGARIERPHDYFCKCTECSQKQKHDSFSH 268 D+ + F+ D+TPIILAAH YEI+ L++KG + +PH+ C C EC DS H Sbjct: 133 DKQFSDFTPDITPIILAAHTNNYEIIKMLVQKGVSVPQPHEVRCNCVECVSSSDVDSLRH 192 Query: 269 SRSRINAYKGLASPAYLSLSSEDPVMTALELSNELAVLANIEKEFKNDYRKLSMQCKDFV 328 SRSR+N YK LASP+ ++LSSEDP +TA +LS EL L+ +E EFK +Y +LS QCK F Sbjct: 193 SRSRLNIYKALASPSLIALSSEDPFLTAFQLSWELQELSKVENEFKAEYEELSHQCKHFA 252 Query: 329 VGLLDLCRNTEEVEAILNGDAETRQPGDFGRPNLSRLKLAIKYEVKKFVAHPNCQQQLLS 388 LLD R++ E+E ILN + D L+RLKLAIKY K+FVA PNCQQ L S Sbjct: 253 KDLLDQTRSSRELELILNFRDDMNLLQDEANNELARLKLAIKYRQKEFVAQPNCQQLLAS 312 Query: 389 IWYENLSGLRQQTMAVKFLVVLAVAIGLPFLALIYWCAPCSKMGKILRGPFMKFVAHAAS 448 WY+ G R++ A K + + + + P L+L Y AP S+ G +R PF+KF+ H AS Sbjct: 313 RWYDEFPGWRRRHWAGKLITCVFIGLMFPLLSLCYLVAPKSRYGLFIRKPFIKFICHTAS 372 Query: 449 FTIFLGL-------LVMNAADRFEGTKLLPNETSTDNARQLFRMKTSCFSWMEMLIISWV 501 + FL L +V N DR +G P T+ + WM I+ WV Sbjct: 373 YLTFLFLLLLASQHIVSNNPDR-QG----PKPTTVE--------------WM---ILPWV 410 Query: 502 IGMIWAECKEIWTQGPKEYLFELWNMLDFGMLAIFAASFIARFMAFWHASKAQSIIDAND 561 +G IW E K++W G ++Y+ + WN++DF M +++ A+ + +A+ Sbjct: 411 LGFIWTEIKQMWDGGFQDYIHDWWNLMDFVMNSLYLATISLKIVAY-------------- 456 Query: 562 TLKDLTKVTLGDNVKYYNL-ARIKWDPTDPQIISEGLYAIAVVLSFSRIAYILPANESFG 620 VKY R W+ P +++E ++AIA + S R+ + AN G Sbjct: 457 -------------VKYSGCKPRDTWEMWHPTLVAEAVFAIANIFSSLRLISLFTANSHLG 503 Query: 621 PLQISLGRTVKDIFKFMVIFIMVFVAFMIGMFNLYSYYIGA-----------KQNEAFTT 669 PLQISLGR + DI KF+ I+ +V +AF G+ LY YY + +QN AF+T Sbjct: 504 PLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFYYENSEGMTCKGIRCERQNNAFST 563 Query: 670 VEESFKTLFWAIFGLSEVKSVVINYNHKFIENIGYVLYGVYNVTMVIVLLNMLIAMINSS 729 + E+ ++LFW+IFGL + + +HKF E +G ++G YNV ++VLLNMLIAM+N+S Sbjct: 564 LFETLQSLFWSIFGLISLYVTNVKADHKFTEFVGATMFGTYNVISLVVLLNMLIAMMNNS 623 Query: 730 FQEIEDDADVEWKFARAKLWFSYFEEGRTLPVPFNLVPSPKSLLYLLLKFKKWMCELIQG 789 +Q I D AD+EWKFAR KLW SYFEEG TLP PFN++PSPKS+ YL+ W+ + Sbjct: 624 YQHIADHADIEWKFARTKLWMSYFEEGGTLPPPFNIIPSPKSICYLI----TWIKVHVFK 679 Query: 790 QKQGFQEDAEMNKRNEEKKFGISGSHEDLSKFSLDKNQLAHNKQSSTRSSEDYHLNSFSN 849 ++ +KR E FG G R++E+ LN Sbjct: 680 RR---------SKRTE--TFGTLGR----------------------RAAENVRLN---- 702 Query: 850 PPRQYQKIMKRLIKRYVLQAQIDKESDE-VNEGELKEIKQDISSLRYELL 898 QYQ++++ L+KRYV D +++E + E KE+KQDISS RYE++ Sbjct: 703 --HQYQEVLRNLVKRYVAAMIRDAKTEEGLTEENFKELKQDISSFRYEVI 750 >6DJS-A nrPDB Length = 676 Score = 524 bits (1350), Expect = e-149, Method: Compositional matrix adjust. Identities = 249/304 (81%), Positives = 273/304 (89%), Gaps = 2/304 (0%) Query: 66 RRQTILREKGRRLANRGPAYMFNDHSTSLSIEEERFLDAAEYGNIPVVRKMLEECHSLNV 125 RR T++REKGRR A RGPA+MFND TSL+ EEERFLDAAEYGNIPVVRKMLEE +LNV Sbjct: 13 RRMTVMREKGRRQAVRGPAFMFNDRGTSLTAEEERFLDAAEYGNIPVVRKMLEESKTLNV 72 Query: 126 NCVDYMGQNALQLAVANEHLEITELLLKKENLSRVGDALLLAISKGYVRIVEAILNHPAF 185 NCVDYMGQNALQLAV NEHLE+TELLLKKENL+R+GDALLLAISKGYVRIVEAILNHP F Sbjct: 73 NCVDYMGQNALQLAVGNEHLEVTELLLKKENLARIGDALLLAISKGYVRIVEAILNHPGF 132 Query: 186 AEGKRLATSPSQSELQQDDFYAYDEDGTRFSHDVTPIILAAHCQEYEIVHTLLRKGARIE 245 A KRL SP + ELQ DDFYAYDEDGTRFS D+TPIILAAHCQ+YE+VH LL KGARIE Sbjct: 133 AASKRLTLSPCEQELQDDDFYAYDEDGTRFSPDITPIILAAHCQKYEVVHMLLMKGARIE 192 Query: 246 RPHDYFCKCTECSQKQKHDSFSHSRSRINAYKGLASPAYLSLSSEDPVMTALELSNELAV 305 RPHDYFCKC +C +KQ+HDSFSHSRSRINAYKGLASPAYLSLSSEDPV+TALELSNELA Sbjct: 193 RPHDYFCKCGDCMEKQRHDSFSHSRSRINAYKGLASPAYLSLSSEDPVLTALELSNELAK 252 Query: 306 LANIEKEFKNDYRKLSMQCKDFVVGLLDLCRNTEEVEAILNGDAETRQPGDFGR--PNLS 363 LANIEKEFKNDYRKLSMQCKDFVVG+LDLCR++EEVEAILNGD E+ +P + R +LS Sbjct: 253 LANIEKEFKNDYRKLSMQCKDFVVGVLDLCRDSEEVEAILNGDLESAEPLEVHRHKASLS 312 Query: 364 RLKL 367 R+KL Sbjct: 313 RVKL 316 Score = 109 bits (273), Expect = 4e-24, Method: Compositional matrix adjust. Identities = 55/68 (80%), Positives = 64/68 (94%) Query: 853 QYQKIMKRLIKRYVLQAQIDKESDEVNEGELKEIKQDISSLRYELLEEKSQNTEDLAELI 912 +YQ+IMKRLIKRYVL+AQ+DKE+DEVNEGELKEIKQDISSLRYELLE+KSQ TE+LA LI Sbjct: 602 RYQQIMKRLIKRYVLKAQVDKENDEVNEGELKEIKQDISSLRYELLEDKSQATEELAILI 661 Query: 913 RKLGERLS 920 KL E+L+ Sbjct: 662 HKLSEKLN 669 >5Z96-A nrPDB Length = 755 Score = 518 bits (1335), Expect = e-147, Method: Compositional matrix adjust. Identities = 323/825 (39%), Positives = 460/825 (55%), Gaps = 118/825 (14%) Query: 92 TSLSIEEERFLDAAEYGNIPVVRKMLEECH---SLNVNCVDYMGQNALQLAVANEHLEIT 148 + LS E+ +L+A E G+ V+K LEE +N+NC+D +G+ AL +A+ NE+LE+ Sbjct: 27 SELSPSEKAYLNAVEKGDYASVKKSLEEAEIYFKININCIDPLGRTALLIAIENENLELI 86 Query: 149 ELLLKKENLSRVGDALLLAISKGYVRIVEAILNHPAFAEGKRLATSPSQSELQQDDFYAY 208 ELLL VGDALL AI K V VE +LNH PS +Q Sbjct: 87 ELLLSFN--VYVGDALLHAIRKEVVGAVELLLNH----------KKPSGE--KQVPPILL 132 Query: 209 DEDGTRFSHDVTPIILAAHCQEYEIVHTLLRKGARIERPHDYFCKCTECSQKQKHDSFSH 268 D+ + F+ D+TPIILAAH YEI+ L++KG + RPH+ C C EC DS H Sbjct: 133 DKQFSEFTPDITPIILAAHTNNYEIIKLLVQKGVSVPRPHEVRCNCVECVSSSDVDSLRH 192 Query: 269 SRSRINAYKGLASPAYLSLSSEDPVMTALELSNELAVLANIEKEFKNDYRKLSMQCKDFV 328 SRSR+N YK LASP+ ++LSSEDP +TA +LS EL L+ +E EFK++Y +LS QCK F Sbjct: 193 SRSRLNIYKALASPSLIALSSEDPFLTAFQLSWELQELSKVENEFKSEYEELSRQCKQFA 252 Query: 329 VGLLDLCRNTEEVEAILNGDAETRQPGDFGRPNLSRLKLAIKYEVKKFVAHPNCQQQLLS 388 LLD R++ E+E ILN + + +L+RLKLAIKY K+FVA PNCQQ L S Sbjct: 253 KDLLDQTRSSRELEIILNYRDDNSLIEEQSGNDLARLKLAIKYRQKEFVAQPNCQQLLAS 312 Query: 389 IWYENLSGLRQQTMAVKFLVVLAVAIGLPFLALIYWCAPCSKMGKILRGPFMKFVAHAAS 448 WY+ G R++ AVK + + + P ++ Y AP S +G +R PF+KF+ H AS Sbjct: 313 RWYDEFPGWRRRHWAVKMVTCFIIGLLFPVFSVCYLIAPKSPLGLFIRKPFIKFICHTAS 372 Query: 449 FTIFLGLLVMNAA--DRFEGTKLLPNETSTDNARQLFRMKTSCFSWMEMLIISWVIGMIW 506 + FL LL++ + DR + + P T + WM I+ WV+G IW Sbjct: 373 YLTFLFLLLLASQHIDRSDLNRQGPPPTIVE--------------WM---ILPWVLGFIW 415 Query: 507 AECKEIWTQGPKEYLFELWNMLDFGMLAIFAASFIARFMAFWHASKAQSIIDANDTLKDL 566 E K++W G ++Y+ + WN++DF M +++ A+ + +AF Sbjct: 416 GEIKQMWDGGLQDYIHDWWNLMDFVMNSLYLATISLKIVAF------------------- 456 Query: 567 TKVTLGDNVKYYNL-ARIKWDPTDPQIISEGLYAIAVVLSFSRIAYILPANESFGPLQIS 625 VKY L R WD P +++E L+AIA + S R+ + AN GPLQIS Sbjct: 457 --------VKYSALNPRESWDMWHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQIS 508 Query: 626 LGRTVKDIFKFMVIFIMVFVAFMIGMFNLYSYYIGA-----------KQNEAFTTVEESF 674 LGR + DI KF+ I+ +V +AF G+ LY YY KQN AF+T+ E+ Sbjct: 509 LGRMLLDILKFLFIYCLVLLAFANGLNQLYFYYEETKGLSCKGIRCEKQNNAFSTLFETL 568 Query: 675 KTLFWAIFGLSEVKSVVINYNHKFIENIGYVLYGVYNVTMVIVLLNMLIAMINSSFQEIE 734 ++LFW+IFGL + + H+F E +G ++G YNV ++VLLNMLIAM+N+S+Q I Sbjct: 569 QSLFWSIFGLINLYVTNVKAQHEFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIA 628 Query: 735 DDADVEWKFARAKLWFSYFEEGRTLPVPFNLVPSPKSLLYLLLKFKKWMCELIQGQKQGF 794 D AD+EWKFAR KLW SYFEEG TLP PFN++PSPKSL YL+ KW+ + +K Sbjct: 629 DHADIEWKFARTKLWMSYFEEGGTLPTPFNVIPSPKSLWYLV----KWIWTHLCKKKM-- 682 Query: 795 QEDAEMNKRNEEKKFGISGSHEDLSKFSLDKNQLAHNKQSSTRSSEDYHLNSFSNPPRQY 854 R + + FG G R++++ + QY Sbjct: 683 --------RRKPESFGTIGR----------------------RAADNLRRH------HQY 706 Query: 855 QKIMKRLIKRYVLQAQIDKESDE-VNEGELKEIKQDISSLRYELL 898 Q++M+ L+KRYV + +++E + E +KE+KQDISS R+E+L Sbjct: 707 QEVMRNLVKRYVAAMIREAKTEEGLTEENVKELKQDISSFRFEVL 751 >6BWF-A nrPDB Length = 954 Score = 58.2 bits (139), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 52/240 (21%), Positives = 107/240 (44%), Gaps = 24/240 (10%) Query: 597 LYAIAVVLSFSRIAYILPANESFGPLQISLGRTVKDIFKFMVIFIMVFVAFMIGMFNLYS 656 +Y + ++ + R+ L N+ GP + +G+ V ++F +VI +V ++F + + Sbjct: 618 IYCLNIIFWYVRLLDFLAVNQQAGPYVMMIGKMVANMFYIVVIMALVLLSFGVPRKAI-- 675 Query: 657 YYIGAKQNEAFTTVEESFKTLFWAIFGLSEVKSVVINYNHKFIENI-------GYVLYGV 709 + + +++ ++ +W IFG + + N + I L V Sbjct: 676 --LYPHEEPSWSLAKDIVFHPYWMIFGEVYAYEIDVCANDSTLPTICGPGTWLTPFLQAV 733 Query: 710 YNVTMVIVLLNMLIAMINSSFQEIEDDADVEWKFARAKLWFSYFEEGRTLPVPFNLVPSP 769 Y I+++N+LIA N+ + +++ +++ WK+ R +Y E+ LP P ++ Sbjct: 734 YLFVQYIIMVNLLIAFFNNVYLQVKAISNIVWKYQRYHFIMAYHEKP-VLPPPLIILSHI 792 Query: 770 KSLLYLLLKFKK----------WMCELIQGQKQGFQED-AEMNKRNEEKKFGISGSHEDL 818 SL + K +K ++ E Q + F+E EM ++ KF SGS E + Sbjct: 793 VSLFCCVCKRRKKDKTSDGPKLFLTEEDQKKLHDFEEQCVEMYFDEKDDKFN-SGSEERI 851 >5AQA-A nrPDB Length = 418 Score = 56.2 bits (134), Expect = 6e-08, Method: Compositional matrix adjust. Identities = 67/244 (27%), Positives = 102/244 (41%), Gaps = 42/244 (17%) Query: 100 RFLDAAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLAVANEHLEITELLLKKENLSR 159 + L+AA G VR ++ + +VN D G L LA + HLEI E+LLK Sbjct: 17 KLLEAARAGQDDEVRILM--ANGADVNAADNTGTTPLHLAAYSGHLEIVEVLLKHGADVD 74 Query: 160 VGDA-----LLLAISKGYVRIVEAILNHPAFAEGKRLATSPSQSELQQDDFYAYDEDGTR 214 D L LA G++ IVE +L + A D A D DG Sbjct: 75 ASDVFGYTPLHLAAYWGHLEIVEVLLKNGA-------------------DVNAMDSDG-- 113 Query: 215 FSHDVTPIILAAHCQEYEIVHTLLRKGARIERPHDYFCKCTECSQKQKHDSFSHS--RSR 272 +TP+ LAA EIV LL+ GA ++ + + + Q H + +R Sbjct: 114 ----MTPLHLAAKWGYKEIVEVLLKAGADVDAQDKFGKRPLWLAADQGHAEIAAKLVAAR 169 Query: 273 INAYKG-----LASPAYL-SLSSED--PVMTALELSNELAVLANIEKEFKNDYRKLSMQC 324 + A G L S L S+ SE+ P+M+ ++ A+L+ I+ + R++ Sbjct: 170 LKARVGYIELDLNSGKILESVRSEERFPMMSTFKVLLAGAILSRIDAGQEQLGRRIHYSQ 229 Query: 325 KDFV 328 D V Sbjct: 230 NDLV 233 >5MKE-A nrPDB Length = 968 Score = 55.5 bits (132), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 39/150 (26%), Positives = 69/150 (46%), Gaps = 18/150 (12%) Query: 591 QIISEGLYAIAVVLSFSRIAYILPANESFGPLQISLGRTVKDIFKFMVIFIMVFVAFMIG 650 QI + A+ V + ++ + N + L ++ R KD+F F ++F ++F+A+ Sbjct: 555 QIQFNNIAAVTVFFVWIKLFKFINFNRTMSQLSTTMSRCAKDLFGFAIMFFIIFLAYA-- 612 Query: 651 MFNLYSYYIGAKQNEAFTTVEESFKTLFWAIFGLSEVKSVVINYNHKFIENIGYVLYGVY 710 +Y + Q + F+T +E T F I G + N IE VL +Y Sbjct: 613 ---QLAYLVFGTQVDDFSTFQECIFTQFRIILG---------DINFAEIEEANRVLGPIY 660 Query: 711 ----NVTMVIVLLNMLIAMINSSFQEIEDD 736 M +LLNM +A+IN ++ E++ D Sbjct: 661 FTTFVFFMFFILLNMFLAIINDTYSEVKSD 690 >5AQ9-A nrPDB Length = 422 Score = 54.3 bits (129), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 51/160 (31%), Positives = 67/160 (41%), Gaps = 33/160 (20%) Query: 100 RFLDAAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLAVANEHLEITELLLKKENLSR 159 + L+AA G VR ++ + +VN D G L LA + HLEI E+LLK Sbjct: 17 KLLEAARAGQDDEVRILM--ANGADVNAADNTGTTPLHLAAYSGHLEIVEVLLKHGADVD 74 Query: 160 VGDA-----LLLAISKGYVRIVEAILNHPAFAEGKRLATSPSQSELQQDDFYAYDEDGTR 214 D L LA G++ IVE +L + A D A D DG Sbjct: 75 ASDVFGYTPLHLAAYWGHLEIVEVLLKNGA-------------------DVNAMDSDG-- 113 Query: 215 FSHDVTPIILAAHCQEYEIVHTLLRKGARIERPHDYFCKC 254 +TP+ LAA EIV LL+ GA + D F K Sbjct: 114 ----MTPLHLAAKWGYLEIVEVLLKHGADV-NAQDKFGKT 148 >5MIO-C nrPDB Length = 573 Score = 52.4 bits (124), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 36/86 (41%), Positives = 51/86 (59%), Gaps = 7/86 (8%) Query: 104 AAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLAVANEHLEITELLLKK-ENLSRV-- 160 AA YG++ +V +L+ H +V+ D MG L LA HLEI E+LLK +++ V Sbjct: 450 AATYGHLEIVEVLLK--HGADVSASDLMGSTPLHLAALIGHLEIVEVLLKHGADVNAVDT 507 Query: 161 -GDA-LLLAISKGYVRIVEAILNHPA 184 GD L LA G+++IVEA+L H A Sbjct: 508 WGDTPLRLAAVMGHLKIVEALLKHGA 533 Score = 47.4 bits (111), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 50/160 (31%), Positives = 65/160 (40%), Gaps = 33/160 (20%) Query: 99 ERFLDAAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLAVANEHLEITELLLKKENLS 158 ++ L+AA G VR ++ + +VN D G L LA HLEI E+LLK Sbjct: 412 KKLLEAARAGQDDEVRVLM--ANGADVNATDASGLTPLHLAATYGHLEIVEVLLKHGADV 469 Query: 159 RVGD-----ALLLAISKGYVRIVEAILNHPAFAEGKRLATSPSQSELQQDDFYAYDEDGT 213 D L LA G++ IVE +L H A D A D G Sbjct: 470 SASDLMGSTPLHLAALIGHLEIVEVLLKHGA-------------------DVNAVDTWGD 510 Query: 214 RFSHDVTPIILAAHCQEYEIVHTLLRKGARIERPHDYFCK 253 TP+ LAA +IV LL+ GA + D F K Sbjct: 511 ------TPLRLAAVMGHLKIVEALLKHGADVN-AQDKFGK 543 >5T4D-A nrPDB Length = 510 Score = 50.8 bits (120), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 39/150 (26%), Positives = 69/150 (46%), Gaps = 18/150 (12%) Query: 591 QIISEGLYAIAVVLSFSRIAYILPANESFGPLQISLGRTVKDIFKFMVIFIMVFVAFMIG 650 QI + A+ V + ++ + N + L ++ R KD+F F ++F ++F+A+ Sbjct: 363 QIQFNNIAAVTVFFVWIKLFKFINFNRTMSQLSTTMSRCAKDLFGFAIMFFIIFLAYA-- 420 Query: 651 MFNLYSYYIGAKQNEAFTTVEESFKTLFWAIFGLSEVKSVVINYNHKFIENIGYVLYGVY 710 +Y + Q + F+T +E T F I G + N IE VL +Y Sbjct: 421 ---QLAYLVFGTQVDDFSTFQECIFTQFRIILG---------DINFAEIEEANRVLGPIY 468 Query: 711 ----NVTMVIVLLNMLIAMINSSFQEIEDD 736 M +LLNM +A+IN ++ E++ D Sbjct: 469 FTTFVFFMFFILLNMFLAIINDTYSEVKSD 498 >6D1W-A nrPDB Length = 740 Score = 50.8 bits (120), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 39/150 (26%), Positives = 69/150 (46%), Gaps = 18/150 (12%) Query: 591 QIISEGLYAIAVVLSFSRIAYILPANESFGPLQISLGRTVKDIFKFMVIFIMVFVAFMIG 650 QI + A+ V + ++ + N + L ++ R KD+F F ++ ++F+A+ Sbjct: 503 QIQFNNIAAVTVFFVWIKLFKFINFNRTMSQLSTTMSRCAKDLFGFAIMPFIIFLAYA-- 560 Query: 651 MFNLYSYYIGAKQNEAFTTVEESFKTLFWAIFGLSEVKSVVINYNHKFIENIGYVLYGVY 710 +Y + Q + F+T +E T F I G + N IE VL +Y Sbjct: 561 ---QLAYLVFGTQVDDFSTFQECIFTQFRIILG---------DINFAEIEEANRVLGPIY 608 Query: 711 NVTMVI----VLLNMLIAMINSSFQEIEDD 736 T V +LLNM +A+IN ++ E++ D Sbjct: 609 FTTFVFFMFFILLNMFLAIINDTYSEVKSD 638 >5H76-A nrPDB Length = 201 Score = 49.7 bits (117), Expect = 6e-06, Method: Composition-based stats. Identities = 48/148 (32%), Positives = 63/148 (42%), Gaps = 32/148 (21%) Query: 100 RFLDAAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLAVANEHLEITELLLKKENLSR 159 + L+AA G VR ++ + +VN D G L LA + HLEI E+LLK Sbjct: 9 KLLEAARAGQDDEVRILM--ANGADVNAADNTGTTPLHLAAYSGHLEIVEVLLKHGADVD 66 Query: 160 VGDA-----LLLAISKGYVRIVEAILNHPAFAEGKRLATSPSQSELQQDDFYAYDEDGTR 214 D L LA G++ IVE +L + A D A D DG Sbjct: 67 ASDVFGYTPLHLAAYWGHLEIVEVLLKNGA-------------------DVNAMDSDG-- 105 Query: 215 FSHDVTPIILAAHCQEYEIVHTLLRKGA 242 +TP+ LAA EIV LL+ GA Sbjct: 106 ----MTPLHLAAKWGYLEIVEVLLKHGA 129 Score = 33.1 bits (74), Expect = 0.52, Method: Composition-based stats. Identities = 30/118 (25%), Positives = 50/118 (42%), Gaps = 29/118 (24%) Query: 131 MGQNALQLAVANEHLEITELLLKKENLSRVGDA----LLLAISKGYVRIVEAILNHPAFA 186 +G+ L+ A A + E+ L+ +++ + L LA G++ IVE +L H A Sbjct: 6 LGRKLLEAARAGQDDEVRILMANGADVNAADNTGTTPLHLAAYSGHLEIVEVLLKHGA-- 63 Query: 187 EGKRLATSPSQSELQQDDFYAYDEDGTRFSHDVTPIILAAHCQEYEIVHTLLRKGARI 244 ++ D + Y TP+ LAA+ EIV LL+ GA + Sbjct: 64 ------------DVDASDVFGY-----------TPLHLAAYWGHLEIVEVLLKNGADV 98 >5AQ7-A nrPDB Length = 418 Score = 47.4 bits (111), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 66/245 (26%), Positives = 99/245 (40%), Gaps = 42/245 (17%) Query: 99 ERFLDAAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLAVANEHLEITELLLK----- 153 ++ L+AA G VR +L + +VN D G L LA HL I E+LLK Sbjct: 16 KKLLEAARAGQDDEVRILL--ANGADVNTADETGFTPLHLAAWEGHLGIVEVLLKNGADV 73 Query: 154 KENLSRVGDALLLAISKGYVRIVEAILNHPAFAEGKRLATSPSQSELQQDDFYAYDEDGT 213 N R L LA G++ IVE +L + A A D GT Sbjct: 74 NANDERGHTPLHLAAYTGHLEIVEVLLKNGA-------------------GVNATDVIGT 114 Query: 214 RFSHDVTPIILAAHCQEYEIVHTLLRKGARIERPHDYFCKCTECSQKQKHDSFSHS--RS 271 P+ LAA EIV LL+ GA ++ + + + Q H + + Sbjct: 115 ------APLHLAAMWGYKEIVEVLLKAGADVDAQDKFGKRPLWLAADQGHAEIAAKLVAA 168 Query: 272 RINAYKG-----LASPAYL-SLSSED--PVMTALELSNELAVLANIEKEFKNDYRKLSMQ 323 R+ A G L S L S+ SE+ P+M+ ++ A+L+ I+ + R++ Sbjct: 169 RLKARVGYIELDLNSGKILESVRSEERFPMMSTFKVLLAGAILSRIDAGQEQLGRRIHYS 228 Query: 324 CKDFV 328 D V Sbjct: 229 QNDLV 233 >6MWQ-A nrPDB Length = 493 Score = 46.2 bits (108), Expect = 7e-05, Method: Compositional matrix adjust. Identities = 49/160 (30%), Positives = 66/160 (41%), Gaps = 33/160 (20%) Query: 99 ERFLDAAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLAVANEHLEITELLLKKENLS 158 ++ L+AA G VR ++ + +VN +D G L LA HLEI E+LLK Sbjct: 7 KKLLEAARAGQDDEVRILM--ANGADVNALDRFGLTPLHLAAQRGHLEIVEVLLKCGADV 64 Query: 159 RVGD-----ALLLAISKGYVRIVEAILNHPAFAEGKRLATSPSQSELQQDDFYAYDEDGT 213 D L LA + G++ IVE +L + A D A D G Sbjct: 65 NAADLWGQTPLHLAATAGHLEIVEVLLKYGA-------------------DVNALDLIGK 105 Query: 214 RFSHDVTPIILAAHCQEYEIVHTLLRKGARIERPHDYFCK 253 TP+ L A EIV LL+ GA + D F K Sbjct: 106 ------TPLHLTAIDGHLEIVEVLLKHGADV-NAQDKFGK 138 >6DU8-A nrPDB Length = 805 Score = 45.8 bits (107), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 37/142 (26%), Positives = 68/142 (47%), Gaps = 18/142 (12%) Query: 599 AIAVVLSFSRIAYILPANESFGPLQISLGRTVKDIFKFMVIFIMVFVAFMIGMFNLYSYY 658 A+ + ++ +I + N++ L +L R KDI F V+F +VF A+ Y Sbjct: 443 AVNLFFAWIKIFKYISFNKTMTQLSSTLARCAKDILGFAVMFFIVFFAYA-----QLGYL 497 Query: 659 IGAKQNEAFTTVEESFKTLFWAIFGLSEVKSVVINYNHKFIEN----IGYVLYGVYNVTM 714 + Q E F+T + T F I G ++++ I+N +G + Y + Sbjct: 498 LFGTQVENFSTFIKCIFTQFRIILG---------DFDYNAIDNANRILGPAYFVTYVFFV 548 Query: 715 VIVLLNMLIAMINSSFQEIEDD 736 VLLNM +A+IN ++ E++++ Sbjct: 549 FFVLLNMFLAIINDTYSEVKEE 570 >6FES-A nrPDB Length = 367 Score = 45.4 bits (106), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 52/163 (31%), Positives = 65/163 (39%), Gaps = 33/163 (20%) Query: 99 ERFLDAAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLAVANEHLEITELLLK----- 153 ++ L+AA G VR +L + +VN D G L LA HL I E+LLK Sbjct: 8 KKLLEAARAGQDDEVRILL--ANGADVNTADETGFTPLHLAAWEGHLGIVEVLLKNGADV 65 Query: 154 KENLSRVGDALLLAISKGYVRIVEAILNHPAFAEGKRLATSPSQSELQQDDFYAYDEDGT 213 N R L LA G++ IVE +L + A A D GT Sbjct: 66 NANDERGHTPLHLAAYTGHLEIVEVLLKNGAGVN-------------------ATDVIGT 106 Query: 214 RFSHDVTPIILAAHCQEYEIVHTLLRKGARIERPHDYFCKCTE 256 P+ LAA EIV LL+ GA R D F K E Sbjct: 107 ------APLHLAAMWGHEEIVEVLLKNGAD-ARAQDKFGKTPE 142 Score = 37.0 bits (84), Expect = 0.045, Method: Compositional matrix adjust. Identities = 36/109 (33%), Positives = 53/109 (48%), Gaps = 10/109 (9%) Query: 104 AAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLAVANEHLEITELLLKK----ENLSR 159 AA G++ +V +L+ +N N D G L LA HLEI E+LLK Sbjct: 46 AAWEGHLGIVEVLLKNGADVNAN--DERGHTPLHLAAYTGHLEIVEVLLKNGAGVNATDV 103 Query: 160 VGDA-LLLAISKGYVRIVEAILNHPAFAEGK-RLATSPSQSELQQDDFY 206 +G A L LA G+ IVE +L + A A + + +P +L +D+ Y Sbjct: 104 IGTAPLHLAAMWGHEEIVEVLLKNGADARAQDKFGKTP--EDLARDNGY 150 >6MHW-A nrPDB Length = 826 Score = 45.1 bits (105), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 31/151 (20%), Positives = 73/151 (48%), Gaps = 6/151 (3%) Query: 599 AIAVVLSFSRIAYILPANESFGPLQISLGRTV-KDIFKFMVIFIMVFVAFMIGMFNLYSY 657 +A+ L ++ + Y +S G + + + + D+ KF+ ++I+ + F + + +L Sbjct: 553 VLAMALGWANMLYYTRGFQSMGMYSVMIQKVILHDVLKFLFVYIVFLLGFGVALASLIEK 612 Query: 658 YI-GAKQNEAFTTVEESFKTLFWAIFGLSEVKSVVINYNHKFIENIGYVLYGVYNVTMVI 716 K ++ + ++ LF GL ++ I N K+ ++L Y + + Sbjct: 613 CPKDNKDCSSYGSFSDAVLELFKLTIGLGDLN---IQQNSKYPILFLFLLI-TYVILTFV 668 Query: 717 VLLNMLIAMINSSFQEIEDDADVEWKFARAK 747 +LLNMLIA++ + + + +++ W+ RA+ Sbjct: 669 LLLNMLIALMGETVENVSKESERIWRLQRAR 699 >5AQB-A nrPDB Length = 428 Score = 45.1 bits (105), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 50/161 (31%), Positives = 67/161 (41%), Gaps = 34/161 (21%) Query: 99 ERFLDAAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLAVANEHLEITELLLKKENLS 158 ++ L+AA G R ++ + +VN +D +G L LA A HLEI E LLK Sbjct: 16 KKLLEAARAGQDDECRILM--ANGADVNALDEVGWTPLHLA-AWGHLEIVECLLKNGADV 72 Query: 159 RVGD-----ALLLAISKGYVRIVEAILNHPAFAEGKRLATSPSQSELQQDDFYAYDEDGT 213 D L LA G++ IVE +L + A D A D+ G Sbjct: 73 NAADIDGYTPLHLAAFSGHLEIVEVLLKYGA-------------------DVNADDQAG- 112 Query: 214 RFSHDVTPIILAAHCQEYEIVHTLLRKGARIERPHDYFCKC 254 TP+ LAA EIV LL+ GA + D F K Sbjct: 113 -----FTPLHLAAIFGHLEIVEVLLKNGADV-NAQDKFGKT 147 Score = 33.5 bits (75), Expect = 0.46, Method: Compositional matrix adjust. Identities = 23/73 (31%), Positives = 39/73 (53%), Gaps = 3/73 (4%) Query: 104 AAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLAVANEHLEITELLLKKENLSRVGDA 163 AA +G++ +V +L+ + +VN D G+ LA+ N + +I E+L K L +V DA Sbjct: 119 AAIFGHLEIVEVLLK--NGADVNAQDKFGKTPRDLAIDNGNEDIAEVLGKAATLVKVKDA 176 Query: 164 L-LLAISKGYVRI 175 L GY+ + Sbjct: 177 ADQLGARVGYIEL 189 >5Z1W-A nrPDB Length = 566 Score = 43.1 bits (100), Expect = 6e-04, Method: Compositional matrix adjust. Identities = 36/142 (25%), Positives = 68/142 (47%), Gaps = 18/142 (12%) Query: 599 AIAVVLSFSRIAYILPANESFGPLQISLGRTVKDIFKFMVIFIMVFVAFMIGMFNLYSYY 658 A+ + ++ +I + N++ L +L R KDI F ++F +VF A+ Y Sbjct: 380 AVNLFFAWIKIFKYISFNKTMTQLSSTLARCAKDILGFAIMFFIVFFAYA-----QLGYL 434 Query: 659 IGAKQNEAFTTVEESFKTLFWAIFGLSEVKSVVINYNHKFIENIGYVL----YGVYNVTM 714 + Q E F+T + T F I G ++++ I+N +L + Y + Sbjct: 435 LFGTQVENFSTFVKCIFTQFRIILG---------DFDYNAIDNANRILGPVYFVTYVFFV 485 Query: 715 VIVLLNMLIAMINSSFQEIEDD 736 VLLNM +A+IN ++ E++++ Sbjct: 486 FFVLLNMFLAIINDTYSEVKEE 507 >6DVZ-A nrPDB Length = 791 Score = 42.0 bits (97), Expect = 0.001, Method: Compositional matrix adjust. Identities = 29/151 (19%), Positives = 73/151 (48%), Gaps = 6/151 (3%) Query: 599 AIAVVLSFSRIAYILPANESFGPLQISLGRTV-KDIFKFMVIFIMVFVAFMIGMFNLYSY 657 +A+ L ++ + +S G + + + + D+ KF+ ++I+ + F + + +L Sbjct: 552 VLAMALGWANMLAYTRGFQSMGMYSVMIQKVILHDVLKFLFVYILFLLGFGVALASLIEK 611 Query: 658 YIGAKQN-EAFTTVEESFKTLFWAIFGLSEVKSVVINYNHKFIENIGYVLYGVYNVTMVI 716 K++ ++ + ++ LF GL ++ I N + ++L Y + + Sbjct: 612 CSKDKKDCSSYGSFSDAVLELFKLTIGLGDLN---IQQNSTYPILFLFLLI-TYVILTFV 667 Query: 717 VLLNMLIAMINSSFQEIEDDADVEWKFARAK 747 +LLNMLIA++ + + + +++ W+ RA+ Sbjct: 668 LLLNMLIALMGETVENVSKESERIWRLQRAR 698 >4OAU-C nrPDB Length = 699 Score = 42.0 bits (97), Expect = 0.001, Method: Compositional matrix adjust. Identities = 30/105 (28%), Positives = 56/105 (53%), Gaps = 5/105 (4%) Query: 84 AYMFNDHSTSLSIEEER----FLDAAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLA 139 ++ DH +++ ER + A E ++ +V+++LE+ H + +N D G+ AL LA Sbjct: 202 THLLLDHGADVNVRGERGKTPLILAVEKKHLGLVQRLLEQEH-IEINDTDSDGKTALLLA 260 Query: 140 VANEHLEITELLLKKENLSRVGDALLLAISKGYVRIVEAILNHPA 184 V + +I ELL K+ + GD ++ A +V+ +L+H A Sbjct: 261 VELKLKKIAELLCKRGASTDCGDLVMTARRNYDHSLVKVLLSHGA 305 Score = 37.4 bits (85), Expect = 0.033, Method: Compositional matrix adjust. Identities = 42/154 (27%), Positives = 72/154 (46%), Gaps = 34/154 (22%) Query: 101 FLDAAEYGNIPVVRKMLEECHSLNVNCVDYMGQNAL---QLAVANEHLE-ITELLLKKE- 155 +DAAE G++ V++ +L+E + +VN D MG+NAL L+ + +E IT LLL Sbjct: 152 LMDAAEKGHVEVLKILLDEMGA-DVNACDNMGRNALIHALLSSDDSDVEAITHLLLDHGA 210 Query: 156 ----NLSRVGDALLLAISKGYVRIVEAILNHPAFAEGKRLATSPSQSELQQDDFYAYDED 211 R L+LA+ K ++ +V+ +L Q ++ +D D D Sbjct: 211 DVNVRGERGKTPLILAVEKKHLGLVQRLL---------------EQEHIEIND---TDSD 252 Query: 212 GTRFSHDVTPIILAAHCQEYEIVHTLLRKGARIE 245 G T ++LA + +I L ++GA + Sbjct: 253 GK------TALLLAVELKLKKIAELLCKRGASTD 280 >5CBO-A nrPDB Length = 176 Score = 40.4 bits (93), Expect = 0.004, Method: Composition-based stats. Identities = 32/91 (35%), Positives = 44/91 (48%), Gaps = 7/91 (7%) Query: 99 ERFLDAAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLAVANEHLEITELLLKKENLS 158 ++ L+AA G VR ++ + +VN +D G L LA H EI E+LLK Sbjct: 5 KKLLEAAHAGQDDEVRILM--ANGADVNAMDNFGVTPLHLAAYWGHFEIVEVLLKYGADV 62 Query: 159 RVGDA-----LLLAISKGYVRIVEAILNHPA 184 DA L LA GY+ IVE +L + A Sbjct: 63 NASDATGDTPLHLAAKWGYLGIVEVLLKYGA 93 >6BPQ-A nrPDB Length = 950 Score = 40.4 bits (93), Expect = 0.004, Method: Compositional matrix adjust. Identities = 88/417 (21%), Positives = 165/417 (39%), Gaps = 112/417 (26%) Query: 365 LKLAIKYEVKKFVAHPNCQQQLLSIWYENLSGLRQQTMAVKFLVVLAV--AIGLPFLALI 422 L+LA++ ++F+A P Q L WY +S + T K ++ L IG F++ Sbjct: 532 LELAVEARDQQFIAQPGVQNFLSKQWYGEIS---RDTKNWKIILCLFFFPLIGCGFIS-- 586 Query: 423 YWCAPCSKMGKIL-------RGPFMKFVAHAASFTIFLGLLVMNAADRFEGTKLLPNETS 475 + P K K+ PF+ F + + FL L F+ Sbjct: 587 FRKKPVEKTKKLFLYYVSFFTSPFVVFSWNVIFYIAFLLLFAYVLLMDFQ---------- 636 Query: 476 TDNARQLFRMKTSCFSWMEMLIISWVIGMIWAECKEIWTQGPKEYLFELWNMLDFGMLAI 535 + T+ +E+++ V ++ E ++ + G K Y +LWN++D LAI Sbjct: 637 --------KEPTA----LEIILYVLVFILLCDEVRQWYMNGSK-YFSDLWNVMD--TLAI 681 Query: 536 FAASFIARFMAFWHASKAQSIIDANDTLKDLTKVTLGDNVKYYNLARIKWDPTDPQIISE 595 F FIA + H+ D +Y+ R+ Sbjct: 682 FY--FIAGIVFRLHS----------------------DESSWYS-GRV------------ 704 Query: 596 GLYAIAVVLSFSRIAYILPANESFGPLQISLGRTVKDIFKFMVIFIMVFVAFMIGMFNLY 655 ++ + ++ R+ +I + + GP I L R + D+F F+ +F + VAF + + Sbjct: 705 -IFCLDYIVFTLRLIHIFTVSRNLGPKIIMLQRMMIDVFFFLFLFAVWMVAFGVARQGIL 763 Query: 656 SYYIGAKQNEAFTTVEESFKTLFW----AIFGL--SEVKSVVINYNH------------- 696 ++NE E F+++ + A+FG ++ N++H Sbjct: 764 ------RKNEH--RWEWIFRSVIYEPYLAMFGQYPDDIDGTTYNFDHCTFSGNESKPLCV 815 Query: 697 --------KFIENIGYVLYGVYNVTMVIVLLNMLIAMINSSFQEIEDDADVEWKFAR 745 +F E I L +Y ++ I+L+N+L+AM + ++++ D WKF R Sbjct: 816 ELDANNQPRFPEWITIPLVCIYMLSTNILLVNLLVAMFGYTVGSVQENNDQVWKFQR 872 >5IRX-A nrPDB Length = 636 Score = 40.0 bits (92), Expect = 0.005, Method: Compositional matrix adjust. Identities = 30/117 (25%), Positives = 56/117 (47%), Gaps = 11/117 (9%) Query: 630 VKDIFKFMVIFIMVFVAFMIGMFNLYSYYIGAKQNEAFTTVEESFKTLFWAIFGLSEVKS 689 ++D+ +FM ++++ F + L K N ++T E FK G+ +++ Sbjct: 469 LRDLCRFMFVYLVFLFGFSTAVVTLIE---DGKYNSLYSTCLELFK----FTIGMGDLE- 520 Query: 690 VVINYNHKFIENIGYVLYGVYNVTMVIVLLNMLIAMINSSFQEIEDDADVEWKFARA 746 NY+ K + +L Y + I+LLNMLIA++ + +I ++ WK RA Sbjct: 521 FTENYDFK---AVFIILLLAYVILTYILLLNMLIALMGETVNKIAQESKNIWKLQRA 574 >5GP7-A nrPDB Length = 169 Score = 37.7 bits (86), Expect = 0.026, Method: Composition-based stats. Identities = 22/55 (40%), Positives = 32/55 (58%), Gaps = 5/55 (9%) Query: 101 FLDAAEYGNIPVVRKMLEECHSLNVNCVDYMGQNA--LQLAVANEHLEITELLLK 153 LDAA+ G + V+K+ C N+NC D G+N+ L LA +LE+ E LL+ Sbjct: 13 LLDAAKKGCLARVQKL---CTPENINCRDTQGRNSTPLHLAAGYNNLEVAEYLLE 64 Score = 32.3 bits (72), Expect = 1.1, Method: Composition-based stats. Identities = 27/86 (31%), Positives = 37/86 (43%), Gaps = 7/86 (8%) Query: 104 AAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLAVANEHLEITELLLKKENLSRVGDA 163 AA Y N+ V +LE H +VN D G L A + H++I LL+K D Sbjct: 50 AAGYNNLEVAEYLLE--HGADVNAQDKGGLIPLHNAASYGHVDIAALLIKYNTCVNATDK 107 Query: 164 -----LLLAISKGYVRIVEAILNHPA 184 L A KG ++ +L H A Sbjct: 108 WAFTPLHEAAQKGRTQLCALLLAHGA 133 >6BBJ-A nrPDB Length = 868 Score = 35.8 bits (81), Expect = 0.082, Method: Compositional matrix adjust. Identities = 34/178 (19%), Positives = 75/178 (42%), Gaps = 15/178 (8%) Query: 596 GLYAIAVVLSFSRIAYILPANESFGPLQISLGRTV-KDIFKFMVIFIMVFVAF---MIGM 651 + A+VL + Y + G I L + + KD+F+F++++++ + + ++ + Sbjct: 572 AVMVFALVLGWMNALYFTRGLKLTGTYSIMLQKILFKDLFRFLLVYLLFMIGYASALVSL 631 Query: 652 FNLYSYYIGAKQNEAFTTVEE--------SFKTLFWAIFGLSEVKSVVINYNHKFIENIG 703 N + + + TV E +F +F L+ + N + Sbjct: 632 LNPCTSQESCIETSSNCTVPEYPSCRDSSTFSKFLLDLFKLTIGMGDLEMINSAKYPAVF 691 Query: 704 YVLYGVYNVTMVIVLLNMLIAMINSSFQEIEDDADVEWKFARAKLWFSYFEEGRTLPV 761 +L Y + ++LLNMLIA++ + ++ ++ WK A + + R+ PV Sbjct: 692 IILLVTYIILTFVLLLNMLIALMGETVGQVSKESKQIWKLQWAT---TILDIERSFPV 746 >6BOA-A nrPDB Length = 742 Score = 35.0 bits (79), Expect = 0.16, Method: Compositional matrix adjust. Identities = 27/148 (18%), Positives = 64/148 (43%), Gaps = 12/148 (8%) Query: 599 AIAVVLSFSRIAYILPANESFGPLQISLGRTV-KDIFKFMVIFIMVFVAFMIGMFNLYSY 657 + A+VL + + Y + GP I + + + D+ +F + +V + F + ++ Sbjct: 455 SFALVLGWCNVMYFAEGFQMLGPFTIMIQKMIFGDLMRFCWLMAVVILGFASAFYIIF-- 512 Query: 658 YIGAKQNEAFTTVEESFKTLFWAIFGLSEVKSVVINYNHKFIENIGY---VLYGVYNVTM 714 Q E + F A+F E+ +I+ + ++ + + Y + + Sbjct: 513 -----QTEDPEELGH-FYDYPMALFSTFELFLTIIDGPANYNVDLPFMYSITYAAFAIIA 566 Query: 715 VIVLLNMLIAMINSSFQEIEDDADVEWK 742 +++LN+LIAM+ + + + D W+ Sbjct: 567 TLLMLNLLIAMMGDTHWRVAHERDELWR 594 >4Z68-A nrPDB Length = 155 Score = 34.7 bits (78), Expect = 0.19, Method: Composition-based stats. Identities = 28/86 (32%), Positives = 40/86 (46%), Gaps = 7/86 (8%) Query: 104 AAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLAVANEHLEITELLLKKENLSRVGD- 162 AA Y + VV +L+ H +V+ D G L A + H E+ ELL+K + V D Sbjct: 44 AAGYNRVSVVEYLLQ--HGADVHAKDKGGLVPLHNACSYGHYEVAELLVKHGAVVNVADL 101 Query: 163 ----ALLLAISKGYVRIVEAILNHPA 184 L A +KG I + +L H A Sbjct: 102 WKFTPLHEAAAKGKYEICKLLLQHGA 127 >6C8G-A nrPDB Length = 675 Score = 34.7 bits (78), Expect = 0.21, Method: Compositional matrix adjust. Identities = 34/173 (19%), Positives = 74/173 (42%), Gaps = 15/173 (8%) Query: 601 AVVLSFSRIAYILPANESFGPLQISLGRTV-KDIFKFMVIFIMVFVAF---MIGMFNLYS 656 A+VL + Y + G I L + + KD+F+F++++++ + + ++ + N + Sbjct: 446 ALVLGWMNALYFTRGLKLTGTYSIMLQKILFKDLFRFLLVYLLFMIGYASALVSLLNPCT 505 Query: 657 YYIGAKQNEAFTTVEE--------SFKTLFWAIFGLSEVKSVVINYNHKFIENIGYVLYG 708 + + TV E +F +F L+ + N + +L Sbjct: 506 SQESCIETSSQCTVPEYPSCRDSSTFSKFLLDLFKLTIGMGDLEMINSAKYPAVFIILLV 565 Query: 709 VYNVTMVIVLLNMLIAMINSSFQEIEDDADVEWKFARAKLWFSYFEEGRTLPV 761 Y + ++LLNMLIA++ + ++ ++ WK A + + R+ PV Sbjct: 566 TYIILTFVLLLNMLIALMGETVGQVSKESKQIWKLQWAT---TILDIERSFPV 615 >6BWI-A nrPDB Length = 977 Score = 34.7 bits (78), Expect = 0.22, Method: Compositional matrix adjust. Identities = 17/51 (33%), Positives = 31/51 (60%), Gaps = 1/51 (1%) Query: 716 IVLLNMLIAMINSSFQEIEDDADVEWKFARAKLWFSYFEEGRTLPVPFNLV 766 I+L+N+LIAM + +F +++ ++D+ WK R +L F L PF ++ Sbjct: 834 ILLVNLLIAMFSYTFGKVQGNSDLYWKAQRYRL-IREFHSRPALAPPFIVI 883 >6BY9-A nrPDB Length = 328 Score = 34.3 bits (77), Expect = 0.25, Method: Compositional matrix adjust. Identities = 37/146 (25%), Positives = 60/146 (41%), Gaps = 31/146 (21%) Query: 104 AAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLAVANEHLEITELLLKKENLSRVGDA 163 AAE G++ + +++ N++ + L A N HLE + L+K L DA Sbjct: 109 AAEAGHVDICHMLVQA--GANIDTCSEDQRTPLMEAAENNHLEAVKYLIKAGALVDPKDA 166 Query: 164 -----LLLAISKGYVRIVEAILNHPAFAEGKRLATSPSQSELQQDDFYAYDEDGTRFSHD 218 L LA KG+ +V+ +L++ Q D D+ G Sbjct: 167 EGSTCLHLAAKKGHYEVVQYLLSN------------------GQMDVNCQDDGGW----- 203 Query: 219 VTPIILAAHCQEYEIVHTLLRKGARI 244 TP+I A + ++V LL KG+ I Sbjct: 204 -TPMIWATEYKHVDLVKLLLSKGSDI 228 >6E2G-A nrPDB Length = 727 Score = 33.9 bits (76), Expect = 0.34, Method: Compositional matrix adjust. Identities = 27/148 (18%), Positives = 64/148 (43%), Gaps = 12/148 (8%) Query: 599 AIAVVLSFSRIAYILPANESFGPLQISLGRTV-KDIFKFMVIFIMVFVAFMIGMFNLYSY 657 + A+VL + + Y + GP I + + + D+ +F + +V + F + ++ Sbjct: 454 SFALVLGWCNVMYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMAVVILGFASAFYIIF-- 511 Query: 658 YIGAKQNEAFTTVEESFKTLFWAIFGLSEVKSVVINYNHKFIENIGY---VLYGVYNVTM 714 Q E + F A+F E+ +I+ + ++ + + Y + + Sbjct: 512 -----QTEDPDELGH-FYDYPMALFSTFELFLTIIDGPANYDVDLPFMYSITYAAFAIIA 565 Query: 715 VIVLLNMLIAMINSSFQEIEDDADVEWK 742 +++LN+LIAM+ + + + D W+ Sbjct: 566 TLLMLNLLIAMMGDTHWRVAHERDELWR 593 >6DMR-A nrPDB Length = 730 Score = 33.9 bits (76), Expect = 0.36, Method: Compositional matrix adjust. Identities = 28/148 (18%), Positives = 63/148 (42%), Gaps = 12/148 (8%) Query: 599 AIAVVLSFSRIAYILPANESFGPLQISLGRTV-KDIFKFMVIFIMVFVAFMIGMFNLYSY 657 + A+VL + + Y + GP I + + + D+ +F + +V + F S Sbjct: 455 SFALVLGWCSVMYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMAVVILGFA-------SA 507 Query: 658 YIGAKQNEAFTTVEESFKTLFWAIFGLSEVKSVVINYNHKFIENIGY---VLYGVYNVTM 714 + Q E + E F A+F E+ +I+ + ++ + + Y + + Sbjct: 508 FHITFQTEDPNNLGE-FSDYPTALFSTFELFLTIIDGPANYSVDLPFMYCITYAAFAIIA 566 Query: 715 VIVLLNMLIAMINSSFQEIEDDADVEWK 742 +++LN+ IAM+ + + + D W+ Sbjct: 567 TLLMLNLFIAMMGDTHWRVAQERDELWR 594 >3B7B-A nrPDB Length = 237 Score = 33.1 bits (74), Expect = 0.61, Method: Compositional matrix adjust. Identities = 37/146 (25%), Positives = 60/146 (41%), Gaps = 31/146 (21%) Query: 104 AAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLAVANEHLEITELLLKKENLSRVGDA 163 AAE G++ + +++ N++ + L A N HLE + L+K L DA Sbjct: 18 AAEAGHVDICHMLVQA--GANIDTCSEDQRTPLMEAAENNHLEAVKYLIKAGALVDPKDA 75 Query: 164 -----LLLAISKGYVRIVEAILNHPAFAEGKRLATSPSQSELQQDDFYAYDEDGTRFSHD 218 L LA KG+ +V+ +L++ Q D D+ G Sbjct: 76 EGSTCLHLAAKKGHYEVVQYLLSNG------------------QMDVNCQDDGGW----- 112 Query: 219 VTPIILAAHCQEYEIVHTLLRKGARI 244 TP+I A + ++V LL KG+ I Sbjct: 113 -TPMIWATEYKHVDLVKLLLSKGSDI 137 >5HKP-A nrPDB Length = 351 Score = 32.3 bits (72), Expect = 0.94, Method: Compositional matrix adjust. Identities = 28/86 (32%), Positives = 40/86 (46%), Gaps = 7/86 (8%) Query: 104 AAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLAVANEHLEITELLLKKENLSRVGD- 162 AA Y + +V+ +L+ H +V+ D G L A + H E+TELLLK D Sbjct: 65 AAGYNRVRIVQLLLQ--HGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGACVNAMDL 122 Query: 163 ----ALLLAISKGYVRIVEAILNHPA 184 L A SK V + +L+H A Sbjct: 123 WQFTPLHEAASKNRVEVCSLLLSHGA 148 >5JHQ-A nrPDB Length = 482 Score = 32.0 bits (71), Expect = 1.2, Method: Compositional matrix adjust. Identities = 28/86 (32%), Positives = 40/86 (46%), Gaps = 7/86 (8%) Query: 104 AAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLAVANEHLEITELLLKKENLSRVGD- 162 AA Y + +V+ +L+ H +V+ D G L A + H E+TELLLK D Sbjct: 209 AAGYNRVRIVQLLLQ--HGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGACVNAMDL 266 Query: 163 ----ALLLAISKGYVRIVEAILNHPA 184 L A SK V + +L+H A Sbjct: 267 WQFTPLHEAASKNRVEVCSLLLSHGA 292 >4O1O-A nrPDB Length = 717 Score = 32.0 bits (71), Expect = 1.4, Method: Compositional matrix adjust. Identities = 27/86 (31%), Positives = 44/86 (51%), Gaps = 7/86 (8%) Query: 89 DHSTSLSIEEER----FLDAAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLAVANEH 144 DH +++ E + A E N+ +V+ +LE+ + VN D G+ AL LAV Sbjct: 210 DHGADVNVRGEGSKTPLILAVERKNLDLVQMLLEQ-EQIEVNDTDREGKTALLLAVELRL 268 Query: 145 LEITELLLKKENLSRVGDALLLAISK 170 EI +LL + + GD L+AI++ Sbjct: 269 EEIAKLLCHRGASTNCGD--LVAIAR 292 >1BD8-A nrPDB Length = 156 Score = 31.2 bits (69), Expect = 2.2, Method: Composition-based stats. Identities = 25/85 (29%), Positives = 40/85 (47%), Gaps = 8/85 (9%) Query: 103 DAAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLAVANEHLEITELLLKKENLSRVGD 162 DAA G + ++ ++E H +VN D G + LAV H + L + +L R D Sbjct: 74 DAARTGFLDTLKVLVE--HGADVNVPDGTGALPIHLAVQEGHTAVVSFLAAESDLHR-RD 130 Query: 163 A-----LLLAISKGYVRIVEAILNH 182 A L LA+ +G +V+ + H Sbjct: 131 ARGLTPLELALQRGAQDLVDILQGH 155 >1G3N-B nrPDB Length = 168 Score = 31.2 bits (69), Expect = 2.4, Method: Composition-based stats. Identities = 29/89 (32%), Positives = 37/89 (41%), Gaps = 8/89 (8%) Query: 73 EKGRRLANRGPAYMFNDHSTSLSIEEERFLDAAEYGNIPVVRKMLEECHSLNVNCVDYMG 132 E RRL RG D + I DAA G + ++ +LE +VN D G Sbjct: 51 EIARRLLLRGANPDLKDRTGFAVIH-----DAARAGFLDTLQTLLE--FQADVNIEDNEG 103 Query: 133 QNALQLAVANEHLEITELLLKKENLSRVG 161 L LA HL + E L+ K S VG Sbjct: 104 NLPLHLAAKEGHLRVVEFLV-KHTASNVG 131 >1WG0-A nrPDB Length = 243 Score = 30.8 bits (68), Expect = 2.6, Method: Compositional matrix adjust. Identities = 21/84 (25%), Positives = 40/84 (47%), Gaps = 5/84 (5%) Query: 101 FLDAAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLAVANEHLEITELLLKKENLSRV 160 F A GN+ VV+ + + ++N + G L LAV + E+++ L++ R+ Sbjct: 76 FHIACSVGNLEVVKSLYDRPLKPDLNKITNQGVTCLHLAVGKKWFEVSQFLIENGASVRI 135 Query: 161 GD-----ALLLAISKGYVRIVEAI 179 D L A S G ++++E + Sbjct: 136 KDKFNQIPLHRAASVGSLKLIELL 159 >1OED-B nrPDB Length = 250 Score = 30.4 bits (67), Expect = 4.2, Method: Compositional matrix adjust. Identities = 22/95 (23%), Positives = 44/95 (46%), Gaps = 8/95 (8%) Query: 400 QTMAVKFLVVLAVAIGLPFLALIYWCAPCSKMGKILRGPFMKFVAHAASFTIFLGLLVMN 459 + M++ +LAV + FL L+ P + + + ++ F+ +F++ L ++V+N Sbjct: 31 EKMSLSISALLAVTV---FLLLLADKVPETSLSVPIIIRYLMFIMILVAFSVILSVVVLN 87 Query: 460 AADRFEGTKLLPNETSTDNARQLFRMKTSCFSWME 494 R T +PN RQ+F F W++ Sbjct: 88 LHHRSPNTHTMPNWI-----RQIFIETLPPFLWIQ 117 >4BOT-B nrPDB Length = 493 Score = 29.3 bits (64), Expect = 8.3, Method: Compositional matrix adjust. Identities = 14/56 (25%), Positives = 27/56 (48%), Gaps = 5/56 (8%) Query: 439 FMKFVAHAASFTIFLGLLVMNAADRFEGTKLLPNETSTDNARQLFRMKTSCFSWME 494 ++ F+ +F++ L ++V+N R T +PN RQ+F F W++ Sbjct: 307 YLMFIMILVAFSVILSVVVLNLHHRSPNTHTMPNWI-----RQIFIETLPPFLWIQ 357 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 6CV9-A nrPDB 1261 0.0 6CUD-A nrPDB 1173 0.0 6G1K-A nrPDB 941 0.0 5Z96-A nrPDB 922 0.0 6DJS-A nrPDB 458 e-129 6BWF-A nrPDB 263 3e-70 5AQA-A nrPDB 246 4e-65 5AQ7-A nrPDB 236 2e-62 5AQ9-A nrPDB 230 3e-60 5AQB-A nrPDB 210 3e-54 5H76-A nrPDB 166 3e-41 6FES-A nrPDB 164 2e-40 6MWQ-A nrPDB 161 1e-39 6MHW-A nrPDB 159 7e-39 5MIO-C nrPDB 156 5e-38 6DVZ-A nrPDB 152 6e-37 5MKE-A nrPDB 146 4e-35 5T4D-A nrPDB 146 6e-35 6D1W-A nrPDB 142 8e-34 6DU8-A nrPDB 139 5e-33 5Z1W-A nrPDB 139 6e-33 4OAU-C nrPDB 117 2e-26 Sequences not found previously or not previously below threshold: 5CBO-A nrPDB 116 5e-26 6BPQ-A nrPDB 113 4e-25 6BBJ-A nrPDB 105 9e-23 6C8G-A nrPDB 105 1e-22 5IRX-A nrPDB 103 4e-22 4Z68-A nrPDB 93 4e-19 4O1O-A nrPDB 90 5e-18 5GP7-A nrPDB 89 8e-18 5HKP-A nrPDB 86 6e-17 6BY9-A nrPDB 82 9e-16 3B7B-A nrPDB 82 9e-16 6DMR-A nrPDB 81 2e-15 6BOA-A nrPDB 79 6e-15 6E2G-A nrPDB 79 6e-15 5JHQ-A nrPDB 78 2e-14 5AN8-A nrPDB 77 4e-14 6BWI-A nrPDB 75 2e-13 6OO7-A nrPDB 71 2e-12 4NIK-A nrPDB 68 2e-11 3ZKJ-A nrPDB 68 3e-11 6BO5-A nrPDB 66 6e-11 5HI9-A nrPDB 66 8e-11 2KXP-C nrPDB 66 8e-11 2DWZ-A nrPDB 65 1e-10 2RFA-A nrPDB 62 2e-09 2V1Z-A nrPDB 61 3e-09 3EU9-A nrPDB 61 3e-09 1G3N-B nrPDB 61 3e-09 4DXB-A nrPDB 59 8e-09 3GMW-A nrPDB 59 9e-09 3ZDJ-A nrPDB 59 1e-08 1BLX-B nrPDB 57 4e-08 5ET1-A nrPDB 56 5e-08 1WG0-A nrPDB 56 7e-08 6AUN-A nrPDB 56 8e-08 4QY5-A nrPDB 56 9e-08 3EHQ-A nrPDB 55 1e-07 1BD8-A nrPDB 55 1e-07 5D68-A nrPDB 52 8e-07 3OPP-A nrPDB 52 1e-06 4OT9-A nrPDB 51 2e-06 6AYG-A nrPDB 49 1e-05 1D9S-A nrPDB 49 1e-05 3T9K-A nrPDB 47 2e-05 2A5E-A nrPDB 47 3e-05 5DND-A nrPDB 47 4e-05 3LJN-A nrPDB 47 4e-05 3UI2-A nrPDB 47 4e-05 3DEO-A nrPDB 46 9e-05 6EMK-G nrPDB 46 1e-04 5U0K-A nrPDB 44 3e-04 5U0J-A nrPDB 44 4e-04 3RVY-A nrPDB 43 6e-04 6N4I-A nrPDB 43 7e-04 4N5Q-A nrPDB 43 7e-04 2NYJ-A nrPDB 42 0.001 5UQE-A nrPDB 42 0.001 4BSZ-B nrPDB 42 0.001 6NIQ-A nrPDB 42 0.001 5EK0-A nrPDB 40 0.004 2F37-A nrPDB 40 0.005 2ETB-A nrPDB 39 0.007 3W9G-A nrPDB 38 0.024 4LTR-A nrPDB 37 0.035 5HW3-A nrPDB 36 0.10 6C96-A nrPDB 35 0.13 3LVQ-E nrPDB 34 0.36 2B0O-E nrPDB 34 0.36 5HKD-A nrPDB 34 0.46 4DX2-A nrPDB 34 0.46 4DXW-A nrPDB 33 0.74 6GC1-A nrPDB 32 0.81 4BGN-A nrPDB 32 0.85 5EUA-A nrPDB 32 1.3 6EM5-I nrPDB 32 1.4 5E1J-A nrPDB 32 1.6 6GCS-2 nrPDB 31 1.9 6CMO-R nrPDB 31 1.9 5W0P-A nrPDB 31 1.9 4RM9-A nrPDB 31 1.9 4XD0-A nrPDB 31 2.0 5FQM-A nrPDB 31 2.3 4EDG-A nrPDB 31 3.8 4C6Y-A nrPDB 30 4.2 5FQI-A nrPDB 30 4.3 1G0D-A nrPDB 30 4.4 6NQ0-A nrPDB 30 4.5 6GCS-4 nrPDB 30 5.1 4S1L-A nrPDB 30 5.3 4F61-I nrPDB 29 7.6 4GX0-A nrPDB 29 8.6 >6CV9-A nrPDB Length = 842 Score = 1261 bits (3263), Expect = 0.0, Method: Composition-based stats. Identities = 837/840 (99%), Positives = 838/840 (99%) Query: 91 STSLSIEEERFLDAAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLAVANEHLEITEL 150 + LSIEEERFLDAAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLAVANEHLEITEL Sbjct: 3 GSMLSIEEERFLDAAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLAVANEHLEITEL 62 Query: 151 LLKKENLSRVGDALLLAISKGYVRIVEAILNHPAFAEGKRLATSPSQSELQQDDFYAYDE 210 LLKKENLSRVGDALLLAISKGYVRIVEAILNHPAFAEGKRLATSPSQSELQQDDFYAYDE Sbjct: 63 LLKKENLSRVGDALLLAISKGYVRIVEAILNHPAFAEGKRLATSPSQSELQQDDFYAYDE 122 Query: 211 DGTRFSHDVTPIILAAHCQEYEIVHTLLRKGARIERPHDYFCKCTECSQKQKHDSFSHSR 270 DGTRFSHDVTPIILAAHCQEYEIVHTLLRKGARIERPHDYFCKCTECSQKQKHDSFSHSR Sbjct: 123 DGTRFSHDVTPIILAAHCQEYEIVHTLLRKGARIERPHDYFCKCTECSQKQKHDSFSHSR 182 Query: 271 SRINAYKGLASPAYLSLSSEDPVMTALELSNELAVLANIEKEFKNDYRKLSMQCKDFVVG 330 SRINAYKGLASPAYLSLSSEDPVMTALELSNELAVLANIEKEFKNDYRKLSMQCKDFVVG Sbjct: 183 SRINAYKGLASPAYLSLSSEDPVMTALELSNELAVLANIEKEFKNDYRKLSMQCKDFVVG 242 Query: 331 LLDLCRNTEEVEAILNGDAETRQPGDFGRPNLSRLKLAIKYEVKKFVAHPNCQQQLLSIW 390 LLDLCRNTEEVEAILNGDAETRQPGDFGRPNLSRLKLAIKYEVKKFVAHPNCQQQLLSIW Sbjct: 243 LLDLCRNTEEVEAILNGDAETRQPGDFGRPNLSRLKLAIKYEVKKFVAHPNCQQQLLSIW 302 Query: 391 YENLSGLRQQTMAVKFLVVLAVAIGLPFLALIYWCAPCSKMGKILRGPFMKFVAHAASFT 450 YENLSGLRQQTMAVKFLVVLAVAIGLPFLALIYWCAPCSKMGKILRGPFMKFVAHAASFT Sbjct: 303 YENLSGLRQQTMAVKFLVVLAVAIGLPFLALIYWCAPCSKMGKILRGPFMKFVAHAASFT 362 Query: 451 IFLGLLVMNAADRFEGTKLLPNETSTDNARQLFRMKTSCFSWMEMLIISWVIGMIWAECK 510 IFLGLLVMNAADRFEGTKLLPNETSTDNARQLFRMKTSCFSWMEMLIISWVIGMIWAECK Sbjct: 363 IFLGLLVMNAADRFEGTKLLPNETSTDNARQLFRMKTSCFSWMEMLIISWVIGMIWAECK 422 Query: 511 EIWTQGPKEYLFELWNMLDFGMLAIFAASFIARFMAFWHASKAQSIIDANDTLKDLTKVT 570 EIWTQGPKEYLFELWNMLDFGMLAIFAASFIARFMAFWHASKAQSIIDANDTLKDLTKVT Sbjct: 423 EIWTQGPKEYLFELWNMLDFGMLAIFAASFIARFMAFWHASKAQSIIDANDTLKDLTKVT 482 Query: 571 LGDNVKYYNLARIKWDPTDPQIISEGLYAIAVVLSFSRIAYILPANESFGPLQISLGRTV 630 LGDNVKYYNLARIKWDPTDPQIISEGLYAIAVVLSFSRIAYILPANESFGPLQISLGRTV Sbjct: 483 LGDNVKYYNLARIKWDPTDPQIISEGLYAIAVVLSFSRIAYILPANESFGPLQISLGRTV 542 Query: 631 KDIFKFMVIFIMVFVAFMIGMFNLYSYYIGAKQNEAFTTVEESFKTLFWAIFGLSEVKSV 690 KDIFKFMVIFIMVFVAFMIGMFNLYSYYIGAKQNEAFTTVEESFKTLFWAIFGLSEVKSV Sbjct: 543 KDIFKFMVIFIMVFVAFMIGMFNLYSYYIGAKQNEAFTTVEESFKTLFWAIFGLSEVKSV 602 Query: 691 VINYNHKFIENIGYVLYGVYNVTMVIVLLNMLIAMINSSFQEIEDDADVEWKFARAKLWF 750 VINYNHKFIENIGYVLYGVYNVTMVIVLLNMLIAMINSSFQEIEDDADVEWKFARAKLWF Sbjct: 603 VINYNHKFIENIGYVLYGVYNVTMVIVLLNMLIAMINSSFQEIEDDADVEWKFARAKLWF 662 Query: 751 SYFEEGRTLPVPFNLVPSPKSLLYLLLKFKKWMCELIQGQKQGFQEDAEMNKRNEEKKFG 810 SYFEEGRTLPVPFNLVPSPKSLLYLLLKFKKWMCELIQGQKQGFQEDAEMNKRNEEKKFG Sbjct: 663 SYFEEGRTLPVPFNLVPSPKSLLYLLLKFKKWMCELIQGQKQGFQEDAEMNKRNEEKKFG 722 Query: 811 ISGSHEDLSKFSLDKNQLAHNKQSSTRSSEDYHLNSFSNPPRQYQKIMKRLIKRYVLQAQ 870 ISGSHEDLSKFSLDKNQLAHNKQSSTRSSEDYHLNSFSNPPRQYQKIMKRLIKRYVLQAQ Sbjct: 723 ISGSHEDLSKFSLDKNQLAHNKQSSTRSSEDYHLNSFSNPPRQYQKIMKRLIKRYVLQAQ 782 Query: 871 IDKESDEVNEGELKEIKQDISSLRYELLEEKSQNTEDLAELIRKLGERLSLEPKLEESRR 930 IDKESDEVNEGELKEIKQDISSLRYELLEEKSQNTEDLAELIRKLGERLSLEPKLEESRR Sbjct: 783 IDKESDEVNEGELKEIKQDISSLRYELLEEKSQNTEDLAELIRKLGERLSLEPKLEESRR 842 >6CUD-A nrPDB Length = 806 Score = 1173 bits (3033), Expect = 0.0, Method: Composition-based stats. Identities = 612/829 (73%), Positives = 706/829 (85%), Gaps = 25/829 (3%) Query: 71 LREKGRRLANRGPAYMFNDHSTSLSIEEERFLDAAEYGNIPVVRKMLEECHSLNVNCVDY 130 +REKGRR A RGPA+MFND TSL+ EEERFLDAAEYGNIPVVRKMLEE +LNVNCVDY Sbjct: 1 MREKGRRQAVRGPAFMFNDRGTSLTAEEERFLDAAEYGNIPVVRKMLEESKTLNVNCVDY 60 Query: 131 MGQNALQLAVANEHLEITELLLKKENLSRVGDALLLAISKGYVRIVEAILNHPAFAEGKR 190 MGQNALQLAV NEHLE+TELLLKKENL+R+GDALLLAISKGYVRIVEAILNHP FA KR Sbjct: 61 MGQNALQLAVGNEHLEVTELLLKKENLARIGDALLLAISKGYVRIVEAILNHPGFAASKR 120 Query: 191 LATSPSQSELQQDDFYAYDEDGTRFSHDVTPIILAAHCQEYEIVHTLLRKGARIERPHDY 250 L SP + ELQ DDFYAYDEDGTRFS D+TPIILAAHCQ+YE+VH LL KGARIERPHDY Sbjct: 121 LTLSPCEQELQDDDFYAYDEDGTRFSPDITPIILAAHCQKYEVVHMLLMKGARIERPHDY 180 Query: 251 FCKCTECSQKQKHDSFSHSRSRINAYKGLASPAYLSLSSEDPVMTALELSNELAVLANIE 310 FCKC +C +KQ+HDSFSHSRSRINAYKGLASPAYLSLSSEDPV+TALELSNELA LANIE Sbjct: 181 FCKCGDCMEKQRHDSFSHSRSRINAYKGLASPAYLSLSSEDPVLTALELSNELAKLANIE 240 Query: 311 KEFKNDYRKLSMQCKDFVVGLLDLCRNTEEVEAILNGDAETRQPGDFGR--PNLSRLKLA 368 KEFKNDYRKLSMQCKDFVVG+LDLCR++EEVEAILNGD E+ +P + R +LSR+KLA Sbjct: 241 KEFKNDYRKLSMQCKDFVVGVLDLCRDSEEVEAILNGDLESAEPLEVHRHKASLSRVKLA 300 Query: 369 IKYEVKKFVAHPNCQQQLLSIWYENLSGLRQQTMAVKFLVVLAVAIGLPFLALIYWCAPC 428 IKYEVKKFVAHPNCQQQLL+IWYENLSGLR+QT+A+K LVVL VA+GLPFLA+ YW APC Sbjct: 301 IKYEVKKFVAHPNCQQQLLTIWYENLSGLREQTIAIKCLVVLVVALGLPFLAIGYWIAPC 360 Query: 429 SKMGKILRGPFMKFVAHAASFTIFLGLLVMNAADRFEGTKLLPNETSTDNARQLFRMKTS 488 S++GKILR PFMKFVAHAASF IFLGLLV NA+DRFEG LPN T TD +Q+FR+KT+ Sbjct: 361 SRLGKILRSPFMKFVAHAASFIIFLGLLVFNASDRFEGITTLPNITVTDYPKQIFRVKTT 420 Query: 489 CFSWMEMLIISWVIGMIWAECKEIWTQGPKEYLFELWNMLDFGMLAIFAASFIARFMAFW 548 F+W EMLI+ WV+GM+W+ECKE+W +GP+EY+ +LWN+LDFGML+IF A+F ARF+AF Sbjct: 421 QFTWTEMLIMVWVLGMMWSECKELWLEGPREYILQLWNVLDFGMLSIFIAAFTARFLAFL 480 Query: 549 HASKAQSIIDANDTLKDLTKVTLGDNVKYYNLARIKWDPTDPQIISEGLYAIAVVLSFSR 608 A+KAQ +D+ DL++VTL ++Y+ AR KW P+DPQIISEGLYAIAVVLSFSR Sbjct: 481 QATKAQQYVDSYVQESDLSEVTLPPEIQYFTYARDKWLPSDPQIISEGLYAIAVVLSFSR 540 Query: 609 IAYILPANESFGPLQISLGRTVKDIFKFMVIFIMVFVAFMIGMFNLYSYYIGAKQNEAFT 668 IAYILPANESFGPLQISLGRTVKDIFKFMV+FIMVF AFMIGMF LYSYY+GAK N AFT Sbjct: 541 IAYILPANESFGPLQISLGRTVKDIFKFMVLFIMVFFAFMIGMFILYSYYLGAKVNAAFT 600 Query: 669 TVEESFKTLFWAIFGLSEVKSVVINYNHKFIENIGYVLYGVYNVTMVIVLLNMLIAMINS 728 TVEESFKTLFW+IFGLSEV SVV+ Y+HKFIENIGYVLYG+YNVTMV+VLLNMLIAMINS Sbjct: 601 TVEESFKTLFWSIFGLSEVTSVVLKYDHKFIENIGYVLYGIYNVTMVVVLLNMLIAMINS 660 Query: 729 SFQEIEDDADVEWKFARAKLWFSYFEEGRTLPVPFNLVPSPKSLLYLLLKFKKWMCELIQ 788 S+QEIEDD+DVEWKFAR+KLW SYF++G+TLP PF+LVPSPKS +Y +++ + + Sbjct: 661 SYQEIEDDSDVEWKFARSKLWLSYFDDGKTLPPPFSLVPSPKSFVYFIMR----IVNFPK 716 Query: 789 GQKQGFQEDAEMNKRNEEKKFGISGSHEDLSKFSLDKNQLAHNKQSSTRSSEDYHLNSFS 848 +++ Q+D EM G+ S L+ F+ QS++R E + NS Sbjct: 717 CRRRRLQKDIEM---------GMGNSKSRLNLFT----------QSNSRVFESHSFNSIL 757 Query: 849 NPPRQYQKIMKRLIKRYVLQAQIDKESDEVNEGELKEIKQDISSLRYEL 897 N P +YQ+IMKRLIKRYVL+AQ+DKE+DEVNEGELKEIKQDISSLRYEL Sbjct: 758 NQPTRYQQIMKRLIKRYVLKAQVDKENDEVNEGELKEIKQDISSLRYEL 806 >6G1K-A nrPDB Length = 921 Score = 941 bits (2432), Expect = 0.0, Method: Composition-based stats. Identities = 318/830 (38%), Positives = 454/830 (54%), Gaps = 129/830 (15%) Query: 92 TSLSIEEERFLDAAEYGNIPVVRKMLEECH---SLNVNCVDYMGQNALQLAVANEHLEIT 148 + LS +E+ +L A E G+ V+ LEE +N+NC+D +G+ AL +A+ NE+LEI Sbjct: 27 SELSTQEKSYLSAVEKGDYASVKLALEEAEIYFKININCIDPLGRTALLIAIENENLEII 86 Query: 149 ELLLKKENLSRVGDALLLAISKGYVRIVEAILNHPAFAEGKRLATSPSQSELQQDDFYAY 208 ELLL VGDALL AI K V VE +LNH + K++ Sbjct: 87 ELLLSFN--VYVGDALLHAIRKEVVGAVELLLNHKKPSGEKQVPP------------ILL 132 Query: 209 DEDGTRFSHDVTPIILAAHCQEYEIVHTLLRKGARIERPHDYFCKCTECSQKQKHDSFSH 268 D+ + F+ D+TPIILAAH YEI+ L++KG + +PH+ C C EC DS H Sbjct: 133 DKQFSDFTPDITPIILAAHTNNYEIIKMLVQKGVSVPQPHEVRCNCVECVSSSDVDSLRH 192 Query: 269 SRSRINAYKGLASPAYLSLSSEDPVMTALELSNELAVLANIEKEFKNDYRKLSMQCKDFV 328 SRSR+N YK LASP+ ++LSSEDP +TA +LS EL L+ +E EFK +Y +LS QCK F Sbjct: 193 SRSRLNIYKALASPSLIALSSEDPFLTAFQLSWELQELSKVENEFKAEYEELSHQCKHFA 252 Query: 329 VGLLDLCRNTEEVEAILNGDAETRQPGDFGRPNLSRLKLAIKYEVKKFVAHPNCQQQLLS 388 LLD R++ E+E ILN + D L+RLKLAIKY K+FVA PNCQQ L S Sbjct: 253 KDLLDQTRSSRELELILNFRDDMNLLQDEANNELARLKLAIKYRQKEFVAQPNCQQLLAS 312 Query: 389 IWYENLSGLRQQTMAVKFLVVLAVAIGLPFLALIYWCAPCSKMGKILRGPFMKFVAHAAS 448 WY+ G R++ A K + + + + P L+L Y AP S+ G +R PF+KF+ H AS Sbjct: 313 RWYDEFPGWRRRHWAGKLITCVFIGLMFPLLSLCYLVAPKSRYGLFIRKPFIKFICHTAS 372 Query: 449 FTIFLGL-------LVMNAADRFEGTKLLPNETSTDNARQLFRMKTSCFSWMEMLIISWV 501 + FL L +V N DR P T+ + WM I+ WV Sbjct: 373 YLTFLFLLLLASQHIVSNNPDR-----QGPKPTTVE--------------WM---ILPWV 410 Query: 502 IGMIWAECKEIWTQGPKEYLFELWNMLDFGMLAIFAASFIARFMAFWHASKAQSIIDAND 561 +G IW E K++W G ++Y+ + WN++DF M +++ A+ + +A+ Sbjct: 411 LGFIWTEIKQMWDGGFQDYIHDWWNLMDFVMNSLYLATISLKIVAY-------------- 456 Query: 562 TLKDLTKVTLGDNVKYYNL-ARIKWDPTDPQIISEGLYAIAVVLSFSRIAYILPANESFG 620 VKY R W+ P +++E ++AIA + S R+ + AN G Sbjct: 457 -------------VKYSGCKPRDTWEMWHPTLVAEAVFAIANIFSSLRLISLFTANSHLG 503 Query: 621 PLQISLGRTVKDIFKFMVIFIMVFVAFMIGMFNLYSYYIGA-----------KQNEAFTT 669 PLQISLGR + DI KF+ I+ +V +AF G+ LY YY + +QN AF+T Sbjct: 504 PLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFYYENSEGMTCKGIRCERQNNAFST 563 Query: 670 VEESFKTLFWAIFGLSEVKSVVINYNHKFIENIGYVLYGVYNVTMVIVLLNMLIAMINSS 729 + E+ ++LFW+IFGL + + +HKF E +G ++G YNV ++VLLNMLIAM+N+S Sbjct: 564 LFETLQSLFWSIFGLISLYVTNVKADHKFTEFVGATMFGTYNVISLVVLLNMLIAMMNNS 623 Query: 730 FQEIEDDADVEWKFARAKLWFSYFEEGRTLPVPFNLVPSPKSLLYLLLKFKKWMCELIQG 789 +Q I D AD+EWKFAR KLW SYFEEG TLP PFN++PSPKS+ YL+ W+ + Sbjct: 624 YQHIADHADIEWKFARTKLWMSYFEEGGTLPPPFNIIPSPKSICYLI----TWIKVHVFK 679 Query: 790 QKQGFQEDAEMNKRNEEKKFGISGSHEDLSKFSLDKNQLAHNKQSSTRSSEDYHLNSFSN 849 ++ + FG G R++E+ LN Sbjct: 680 RR-----------SKRTETFGTLGR----------------------RAAENVRLN---- 702 Query: 850 PPRQYQKIMKRLIKRYVLQAQIDKESDE-VNEGELKEIKQDISSLRYELL 898 QYQ++++ L+KRYV D +++E + E KE+KQDISS RYE++ Sbjct: 703 --HQYQEVLRNLVKRYVAAMIRDAKTEEGLTEENFKELKQDISSFRYEVI 750 >5Z96-A nrPDB Length = 755 Score = 922 bits (2383), Expect = 0.0, Method: Composition-based stats. Identities = 321/825 (38%), Positives = 460/825 (55%), Gaps = 118/825 (14%) Query: 92 TSLSIEEERFLDAAEYGNIPVVRKMLEECH---SLNVNCVDYMGQNALQLAVANEHLEIT 148 + LS E+ +L+A E G+ V+K LEE +N+NC+D +G+ AL +A+ NE+LE+ Sbjct: 27 SELSPSEKAYLNAVEKGDYASVKKSLEEAEIYFKININCIDPLGRTALLIAIENENLELI 86 Query: 149 ELLLKKENLSRVGDALLLAISKGYVRIVEAILNHPAFAEGKRLATSPSQSELQQDDFYAY 208 ELLL VGDALL AI K V VE +LNH + K++ Sbjct: 87 ELLLSFN--VYVGDALLHAIRKEVVGAVELLLNHKKPSGEKQVPP------------ILL 132 Query: 209 DEDGTRFSHDVTPIILAAHCQEYEIVHTLLRKGARIERPHDYFCKCTECSQKQKHDSFSH 268 D+ + F+ D+TPIILAAH YEI+ L++KG + RPH+ C C EC DS H Sbjct: 133 DKQFSEFTPDITPIILAAHTNNYEIIKLLVQKGVSVPRPHEVRCNCVECVSSSDVDSLRH 192 Query: 269 SRSRINAYKGLASPAYLSLSSEDPVMTALELSNELAVLANIEKEFKNDYRKLSMQCKDFV 328 SRSR+N YK LASP+ ++LSSEDP +TA +LS EL L+ +E EFK++Y +LS QCK F Sbjct: 193 SRSRLNIYKALASPSLIALSSEDPFLTAFQLSWELQELSKVENEFKSEYEELSRQCKQFA 252 Query: 329 VGLLDLCRNTEEVEAILNGDAETRQPGDFGRPNLSRLKLAIKYEVKKFVAHPNCQQQLLS 388 LLD R++ E+E ILN + + +L+RLKLAIKY K+FVA PNCQQ L S Sbjct: 253 KDLLDQTRSSRELEIILNYRDDNSLIEEQSGNDLARLKLAIKYRQKEFVAQPNCQQLLAS 312 Query: 389 IWYENLSGLRQQTMAVKFLVVLAVAIGLPFLALIYWCAPCSKMGKILRGPFMKFVAHAAS 448 WY+ G R++ AVK + + + P ++ Y AP S +G +R PF+KF+ H AS Sbjct: 313 RWYDEFPGWRRRHWAVKMVTCFIIGLLFPVFSVCYLIAPKSPLGLFIRKPFIKFICHTAS 372 Query: 449 FTIFLGLLVMNAA--DRFEGTKLLPNETSTDNARQLFRMKTSCFSWMEMLIISWVIGMIW 506 + FL LL++ + DR + + P T + WM I+ WV+G IW Sbjct: 373 YLTFLFLLLLASQHIDRSDLNRQGPPPTIVE--------------WM---ILPWVLGFIW 415 Query: 507 AECKEIWTQGPKEYLFELWNMLDFGMLAIFAASFIARFMAFWHASKAQSIIDANDTLKDL 566 E K++W G ++Y+ + WN++DF M +++ A+ + +AF Sbjct: 416 GEIKQMWDGGLQDYIHDWWNLMDFVMNSLYLATISLKIVAF------------------- 456 Query: 567 TKVTLGDNVKYYNL-ARIKWDPTDPQIISEGLYAIAVVLSFSRIAYILPANESFGPLQIS 625 VKY L R WD P +++E L+AIA + S R+ + AN GPLQIS Sbjct: 457 --------VKYSALNPRESWDMWHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQIS 508 Query: 626 LGRTVKDIFKFMVIFIMVFVAFMIGMFNLYSYYIGA-----------KQNEAFTTVEESF 674 LGR + DI KF+ I+ +V +AF G+ LY YY KQN AF+T+ E+ Sbjct: 509 LGRMLLDILKFLFIYCLVLLAFANGLNQLYFYYEETKGLSCKGIRCEKQNNAFSTLFETL 568 Query: 675 KTLFWAIFGLSEVKSVVINYNHKFIENIGYVLYGVYNVTMVIVLLNMLIAMINSSFQEIE 734 ++LFW+IFGL + + H+F E +G ++G YNV ++VLLNMLIAM+N+S+Q I Sbjct: 569 QSLFWSIFGLINLYVTNVKAQHEFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIA 628 Query: 735 DDADVEWKFARAKLWFSYFEEGRTLPVPFNLVPSPKSLLYLLLKFKKWMCELIQGQKQGF 794 D AD+EWKFAR KLW SYFEEG TLP PFN++PSPKSL YL+ KW+ + +K Sbjct: 629 DHADIEWKFARTKLWMSYFEEGGTLPTPFNVIPSPKSLWYLV----KWIWTHLCKKKM-- 682 Query: 795 QEDAEMNKRNEEKKFGISGSHEDLSKFSLDKNQLAHNKQSSTRSSEDYHLNSFSNPPRQY 854 R + + FG G R++++ + QY Sbjct: 683 --------RRKPESFGTIGR----------------------RAADNLRRH------HQY 706 Query: 855 QKIMKRLIKRYVLQAQIDKESDE-VNEGELKEIKQDISSLRYELL 898 Q++M+ L+KRYV + +++E + E +KE+KQDISS R+E+L Sbjct: 707 QEVMRNLVKRYVAAMIREAKTEEGLTEENVKELKQDISSFRFEVL 751 >6DJS-A nrPDB Length = 676 Score = 458 bits (1177), Expect = e-129, Method: Composition-based stats. Identities = 249/304 (81%), Positives = 273/304 (89%), Gaps = 2/304 (0%) Query: 66 RRQTILREKGRRLANRGPAYMFNDHSTSLSIEEERFLDAAEYGNIPVVRKMLEECHSLNV 125 RR T++REKGRR A RGPA+MFND TSL+ EEERFLDAAEYGNIPVVRKMLEE +LNV Sbjct: 13 RRMTVMREKGRRQAVRGPAFMFNDRGTSLTAEEERFLDAAEYGNIPVVRKMLEESKTLNV 72 Query: 126 NCVDYMGQNALQLAVANEHLEITELLLKKENLSRVGDALLLAISKGYVRIVEAILNHPAF 185 NCVDYMGQNALQLAV NEHLE+TELLLKKENL+R+GDALLLAISKGYVRIVEAILNHP F Sbjct: 73 NCVDYMGQNALQLAVGNEHLEVTELLLKKENLARIGDALLLAISKGYVRIVEAILNHPGF 132 Query: 186 AEGKRLATSPSQSELQQDDFYAYDEDGTRFSHDVTPIILAAHCQEYEIVHTLLRKGARIE 245 A KRL SP + ELQ DDFYAYDEDGTRFS D+TPIILAAHCQ+YE+VH LL KGARIE Sbjct: 133 AASKRLTLSPCEQELQDDDFYAYDEDGTRFSPDITPIILAAHCQKYEVVHMLLMKGARIE 192 Query: 246 RPHDYFCKCTECSQKQKHDSFSHSRSRINAYKGLASPAYLSLSSEDPVMTALELSNELAV 305 RPHDYFCKC +C +KQ+HDSFSHSRSRINAYKGLASPAYLSLSSEDPV+TALELSNELA Sbjct: 193 RPHDYFCKCGDCMEKQRHDSFSHSRSRINAYKGLASPAYLSLSSEDPVLTALELSNELAK 252 Query: 306 LANIEKEFKNDYRKLSMQCKDFVVGLLDLCRNTEEVEAILNGDAETRQPGDFGR--PNLS 363 LANIEKEFKNDYRKLSMQCKDFVVG+LDLCR++EEVEAILNGD E+ +P + R +LS Sbjct: 253 LANIEKEFKNDYRKLSMQCKDFVVGVLDLCRDSEEVEAILNGDLESAEPLEVHRHKASLS 312 Query: 364 RLKL 367 R+KL Sbjct: 313 RVKL 316 Score = 122 bits (306), Expect = 7e-28, Method: Composition-based stats. Identities = 55/69 (79%), Positives = 64/69 (92%) Query: 852 RQYQKIMKRLIKRYVLQAQIDKESDEVNEGELKEIKQDISSLRYELLEEKSQNTEDLAEL 911 +YQ+IMKRLIKRYVL+AQ+DKE+DEVNEGELKEIKQDISSLRYELLE+KSQ TE+LA L Sbjct: 601 TRYQQIMKRLIKRYVLKAQVDKENDEVNEGELKEIKQDISSLRYELLEDKSQATEELAIL 660 Query: 912 IRKLGERLS 920 I KL E+L+ Sbjct: 661 IHKLSEKLN 669 >6BWF-A nrPDB Length = 954 Score = 263 bits (672), Expect = 3e-70, Method: Composition-based stats. Identities = 89/481 (18%), Positives = 178/481 (37%), Gaps = 88/481 (18%) Query: 434 ILRGPFMKFVAHAASFTIFLGLLVMNAADRFEGTKLLPNETSTDNARQLFRMKTSCFSWM 493 P +KF + ++ FL L + E LP+ Sbjct: 502 FYHAPIVKFWFNTLAYLGFLMLYTFVVLVKME---QLPSV-------------------Q 539 Query: 494 EMLIISWVIGMIWAECKEIW-------TQGPKEYLFELWNMLDFGMLAIFAASFIARFMA 546 E ++I+++ + +E++ +Q K + + +N+ D + F F RF A Sbjct: 540 EWIVIAYIFTYAIEKVREVFMSEAGKISQKIKVWFSDYFNVSDTIAIISFFVGFGLRFGA 599 Query: 547 FWHASKAQSIIDANDTLKDLTKVTLGDNVKYYNLARIKWDPTDPQIISEGLYAIAVVLSF 606 W+ I+A D + +Y + ++ + Sbjct: 600 KWN------YINAYDN--------------------------HVFVAGRLIYCLNIIFWY 627 Query: 607 SRIAYILPANESFGPLQISLGRTVKDIFKFMVIFIMVFVAFMIGMFNLYSYYIGAKQNEA 666 R+ L N+ GP + +G+ V ++F +VI +V ++F + + + + + Sbjct: 628 VRLLDFLAVNQQAGPYVMMIGKMVANMFYIVVIMALVLLSFGVPRKAI----LYPHEEPS 683 Query: 667 FTTVEESFKTLFWAIFGLSEVKSVVINYNHKFIENI-------GYVLYGVYNVTMVIVLL 719 ++ ++ +W IFG + + N + I L VY I+++ Sbjct: 684 WSLAKDIVFHPYWMIFGEVYAYEIDVCANDSTLPTICGPGTWLTPFLQAVYLFVQYIIMV 743 Query: 720 NMLIAMINSSFQEIEDDADVEWKFARAKLWFSYFEEGRTLPVPFNLVPSPKSLLYLLLKF 779 N+LIA N+ + +++ +++ WK+ R +Y E+ LP P ++ SL + K Sbjct: 744 NLLIAFFNNVYLQVKAISNIVWKYQRYHFIMAYHEKP-VLPPPLIILSHIVSLFCCVCKR 802 Query: 780 KK----------WMCELIQGQKQGFQED-AEMNKRNEEKKFGISGSHEDLSK-FSLDKNQ 827 +K ++ E Q + F+E EM ++ KF SGS E + F + Sbjct: 803 RKKDKTSDGPKLFLTEEDQKKLHDFEEQCVEMYFDEKDDKFN-SGSEERIRVTFERVEQM 861 Query: 828 LAHNKQSSTRS-SEDYHLNSFSNPPRQYQKIMKRLIKRY-VLQAQIDKESDEVNEGELKE 885 K+ R L S + Q + + L AQ E+ +V+ +E Sbjct: 862 SIQIKEVGDRVNYIKRSLQSLDSQIGHLQDLSALTVDTLKTLTAQKASEASKVHNEITRE 921 Query: 886 I 886 + Sbjct: 922 L 922 Score = 34.4 bits (77), Expect = 0.27, Method: Composition-based stats. Identities = 23/108 (21%), Positives = 45/108 (41%), Gaps = 6/108 (5%) Query: 304 AVLANIEKEFKNDYRKLSMQCKDFVVGLLDLCRNTEEVEAILNGDAETRQPGDFGRPNLS 363 A +++ + + ++ S V LL+ +E A+ T + ++ Sbjct: 320 AKQSDLVDDTSEELKQYSNDFGQLAVELLEQSFRQDETMAM---KLLTYELKNWSNSTC- 375 Query: 364 RLKLAIKYEVKKFVAHPNCQQQLLSIWYENLSGLRQQTMAVKFLVVLA 411 LKLA+ ++ FVAH Q L +W L+ +R+ + L +L Sbjct: 376 -LKLAVSSRLRPFVAHTCTQMLLSDMWMGRLN-MRKNSWYKVILSILV 421 >5AQA-A nrPDB Length = 418 Score = 246 bits (627), Expect = 4e-65, Method: Composition-based stats. Identities = 68/253 (26%), Positives = 104/253 (41%), Gaps = 45/253 (17%) Query: 91 STSLSIEEERFLDAAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLAVANEHLEITEL 150 + L + L+AA G VR ++ + +VN D G L LA + HLEI E+ Sbjct: 11 GSDL---GRKLLEAARAGQDDEVRILM--ANGADVNAADNTGTTPLHLAAYSGHLEIVEV 65 Query: 151 LLKKENLSRVGD-----ALLLAISKGYVRIVEAILNHPAFAEGKRLATSPSQSELQQDDF 205 LLK D L LA G++ IVE +L + A D Sbjct: 66 LLKHGADVDASDVFGYTPLHLAAYWGHLEIVEVLLKNGA-------------------DV 106 Query: 206 YAYDEDGTRFSHDVTPIILAAHCQEYEIVHTLLRKGARIERPHDYFCKCTECSQKQKHDS 265 A D DG +TP+ LAA EIV LL+ GA ++ + + + Q H Sbjct: 107 NAMDSDG------MTPLHLAAKWGYKEIVEVLLKAGADVDAQDKFGKRPLWLAADQGHAE 160 Query: 266 FSHS--RSRINAYKG-----LASPAYL-SLSSED--PVMTALELSNELAVLANIEKEFKN 315 + +R+ A G L S L S+ SE+ P+M+ ++ A+L+ I+ + Sbjct: 161 IAAKLVAARLKARVGYIELDLNSGKILESVRSEERFPMMSTFKVLLAGAILSRIDAGQEQ 220 Query: 316 DYRKLSMQCKDFV 328 R++ D V Sbjct: 221 LGRRIHYSQNDLV 233 >5AQ7-A nrPDB Length = 418 Score = 236 bits (603), Expect = 2e-62, Method: Composition-based stats. Identities = 66/253 (26%), Positives = 100/253 (39%), Gaps = 45/253 (17%) Query: 91 STSLSIEEERFLDAAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLAVANEHLEITEL 150 + L ++ L+AA G VR +L + +VN D G L LA HL I E+ Sbjct: 11 GSDL---GKKLLEAARAGQDDEVRILL--ANGADVNTADETGFTPLHLAAWEGHLGIVEV 65 Query: 151 LLKKENLSRVGD-----ALLLAISKGYVRIVEAILNHPAFAEGKRLATSPSQSELQQDDF 205 LLK D L LA G++ IVE +L + A Sbjct: 66 LLKNGADVNANDERGHTPLHLAAYTGHLEIVEVLLKNGAG-------------------V 106 Query: 206 YAYDEDGTRFSHDVTPIILAAHCQEYEIVHTLLRKGARIERPHDYFCKCTECSQKQKHDS 265 A D GT P+ LAA EIV LL+ GA ++ + + + Q H Sbjct: 107 NATDVIGT------APLHLAAMWGYKEIVEVLLKAGADVDAQDKFGKRPLWLAADQGHAE 160 Query: 266 FSHS--RSRINAYKG-----LASPAYL-SLSSED--PVMTALELSNELAVLANIEKEFKN 315 + +R+ A G L S L S+ SE+ P+M+ ++ A+L+ I+ + Sbjct: 161 IAAKLVAARLKARVGYIELDLNSGKILESVRSEERFPMMSTFKVLLAGAILSRIDAGQEQ 220 Query: 316 DYRKLSMQCKDFV 328 R++ D V Sbjct: 221 LGRRIHYSQNDLV 233 >5AQ9-A nrPDB Length = 422 Score = 230 bits (585), Expect = 3e-60, Method: Composition-based stats. Identities = 66/257 (25%), Positives = 102/257 (39%), Gaps = 49/257 (19%) Query: 91 STSLSIEEERFLDAAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLAVANEHLEITEL 150 + L + L+AA G VR ++ + +VN D G L LA + HLEI E+ Sbjct: 11 GSDL---GRKLLEAARAGQDDEVRILM--ANGADVNAADNTGTTPLHLAAYSGHLEIVEV 65 Query: 151 LLKKENLSRVGD-----ALLLAISKGYVRIVEAILNHPAFAEGKRLATSPSQSELQQDDF 205 LLK D L LA G++ IVE +L + A D Sbjct: 66 LLKHGADVDASDVFGYTPLHLAAYWGHLEIVEVLLKNGA-------------------DV 106 Query: 206 YAYDEDGTRFSHDVTPIILAAHCQEYEIVHTLLRKGARIERPHDYFCKCTECSQKQKHD- 264 A D DG +TP+ LAA EIV LL+ GA + + + + +D Sbjct: 107 NAMDSDG------MTPLHLAAKWGYLEIVEVLLKHGADVNAQDKFGKTPFDLADDNGNDD 160 Query: 265 -----SFSHSRSRINAYKG-----LASPAYL-SLSSED--PVMTALELSNELAVLANIEK 311 + + ++ A G L S L S SE+ P+M+ ++ A+L+ I+ Sbjct: 161 VGTLLQVAAAADQLGARVGYIELDLNSGKILESFRSEERFPMMSTFKVLLAGAILSRIDA 220 Query: 312 EFKNDYRKLSMQCKDFV 328 + R++ D V Sbjct: 221 GQEQLGRRIHYSQNDLV 237 >5AQB-A nrPDB Length = 428 Score = 210 bits (533), Expect = 3e-54, Method: Composition-based stats. Identities = 66/265 (24%), Positives = 103/265 (38%), Gaps = 59/265 (22%) Query: 91 STSLSIEEERFLDAAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLAVANEHLEITEL 150 + L ++ L+AA G R ++ + +VN +D +G L LA HLEI E Sbjct: 11 GSDL---GKKLLEAARAGQDDECRILM--ANGADVNALDEVGWTPLHLAAW-GHLEIVEC 64 Query: 151 LLKKENLSRVGD-----ALLLAISKGYVRIVEAILNHPAFAEGKRLATSPSQSELQQDDF 205 LLK D L LA G++ IVE +L + A D Sbjct: 65 LLKNGADVNAADIDGYTPLHLAAFSGHLEIVEVLLKYGA-------------------DV 105 Query: 206 YAYDEDGTRFSHDVTPIILAAHCQEYEIVHTLLRKGARIERPHDYFCKCT-ECSQKQKHD 264 A D+ G TP+ LAA EIV LL+ GA + D F K + + ++ Sbjct: 106 NADDQAG------FTPLHLAAIFGHLEIVEVLLKNGADV-NAQDKFGKTPRDLAIDNGNE 158 Query: 265 SFSH-------------SRSRINAYKG-----LASPAYL-SLSSED--PVMTALELSNEL 303 + + ++ A G L S L S SE+ P+M+ ++ Sbjct: 159 DIAEVLGKAATLVKVKDAADQLGARVGYIELDLNSGKILESFRSEERFPMMSTFKVLLAG 218 Query: 304 AVLANIEKEFKNDYRKLSMQCKDFV 328 A+L+ I+ + R++ D V Sbjct: 219 AILSRIDAGQEQLGRRIHYSQNDLV 243 >5H76-A nrPDB Length = 201 Score = 166 bits (421), Expect = 3e-41, Method: Composition-based stats. Identities = 52/176 (29%), Positives = 71/176 (40%), Gaps = 35/176 (19%) Query: 98 EERFLDAAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLAVANEHLEITELLLKKENL 157 + L+AA G VR ++ + +VN D G L LA + HLEI E+LLK Sbjct: 7 GRKLLEAARAGQDDEVRILM--ANGADVNAADNTGTTPLHLAAYSGHLEIVEVLLKHGAD 64 Query: 158 SRVGD-----ALLLAISKGYVRIVEAILNHPAFAEGKRLATSPSQSELQQDDFYAYDEDG 212 D L LA G++ IVE +L + A D A D DG Sbjct: 65 VDASDVFGYTPLHLAAYWGHLEIVEVLLKNGA-------------------DVNAMDSDG 105 Query: 213 TRFSHDVTPIILAAHCQEYEIVHTLLRKGARIERPHDYFCKCT-ECSQKQKHDSFS 267 +TP+ LAA EIV LL+ GA D F K + S ++ + Sbjct: 106 ------MTPLHLAAKWGYLEIVEVLLKHGA--VNAQDKFGKTAFDISIDNGNEDLA 153 Score = 62.9 bits (151), Expect = 7e-10, Method: Composition-based stats. Identities = 25/112 (22%), Positives = 37/112 (33%), Gaps = 25/112 (22%) Query: 155 ENLSRVGDALLLAISKGYVRIVEAILNHPAFAEGKRLATSPSQSELQQDDFYAYDEDGTR 214 + +G LL A G V ++ + A D A D GT Sbjct: 1 GSHMDLGRKLLEAARAGQDDEVRILMANGA-------------------DVNAADNTGT- 40 Query: 215 FSHDVTPIILAAHCQEYEIVHTLLRKGARIERPHDYFCKCTECSQKQKHDSF 266 TP+ LAA+ EIV LL+ GA ++ + + H Sbjct: 41 -----TPLHLAAYSGHLEIVEVLLKHGADVDASDVFGYTPLHLAAYWGHLEI 87 Score = 38.2 bits (87), Expect = 0.017, Method: Composition-based stats. Identities = 13/70 (18%), Positives = 33/70 (47%), Gaps = 7/70 (10%) Query: 86 MFNDHSTSLSIEEER----FLDAAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLAVA 141 + + ++ + AA++G + +V +L+ H VN D G+ A +++ Sbjct: 90 VLLKNGADVNAMDSDGMTPLHLAAKWGYLEIVEVLLK--HGA-VNAQDKFGKTAFDISID 146 Query: 142 NEHLEITELL 151 N + ++ ++L Sbjct: 147 NGNEDLAQIL 156 >6FES-A nrPDB Length = 367 Score = 164 bits (414), Expect = 2e-40, Method: Composition-based stats. Identities = 53/183 (28%), Positives = 72/183 (39%), Gaps = 37/183 (20%) Query: 91 STSLSIEEERFLDAAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLAVANEHLEITEL 150 + L ++ L+AA G VR +L + +VN D G L LA HL I E+ Sbjct: 3 GSDL---GKKLLEAARAGQDDEVRILL--ANGADVNTADETGFTPLHLAAWEGHLGIVEV 57 Query: 151 LLKKENLSRVGD-----ALLLAISKGYVRIVEAILNHPAFAEGKRLATSPSQSELQQDDF 205 LLK D L LA G++ IVE +L + A Sbjct: 58 LLKNGADVNANDERGHTPLHLAAYTGHLEIVEVLLKNGAG-------------------V 98 Query: 206 YAYDEDGTRFSHDVTPIILAAHCQEYEIVHTLLRKGARIERPHDYFCKCTE-CSQKQKHD 264 A D GT P+ LAA EIV LL+ GA R D F K E ++ ++ Sbjct: 99 NATDVIGT------APLHLAAMWGHEEIVEVLLKNGAD-ARAQDKFGKTPEDLARDNGYE 151 Query: 265 SFS 267 S + Sbjct: 152 SVA 154 Score = 62.1 bits (149), Expect = 1e-09, Method: Composition-based stats. Identities = 39/216 (18%), Positives = 66/216 (30%), Gaps = 45/216 (20%) Query: 155 ENLSRVGDALLLAISKGYVRIVEAILNHPAFAEGKRLATSPSQSELQQD----------- 203 S +G LL A G V +L + A + Sbjct: 1 GPGSDLGKKLLEAARAGQDDEVRILLANGADVNTADETGFTPLHLAAWEGHLGIVEVLLK 60 Query: 204 ---DFYAYDEDGTRFSHDVTPIILAAHCQEYEIVHTLLRKGARIERPHDYFCKCTECSQK 260 D A DE G TP+ LAA+ EIV LL+ GA + + Sbjct: 61 NGADVNANDERGH------TPLHLAAYTGHLEIVEVLLKNGAGVNATDVIGTAPLHLAAM 114 Query: 261 QKHDSFSHSRSRINAYKGLASPAYLSLSSEDPVMTALELSNELAVLANIEKEFKNDYRKL 320 H+ L + A ++D E LA + +++ R Sbjct: 115 WGHEEI--------VEVLLKNGA--DARAQDKFGKTPE------DLAR-DNGYESVAR-- 155 Query: 321 SMQCKDFVVGLLDLCRNTEEVEAILNGDAETRQPGD 356 + K+ + ++D + E I N + + ++ Sbjct: 156 -LARKEIIRAVVDELK-----ELIQNVNDDIKEVEK 185 Score = 34.4 bits (77), Expect = 0.22, Method: Composition-based stats. Identities = 12/72 (16%), Positives = 27/72 (37%), Gaps = 6/72 (8%) Query: 86 MFNDHSTSLSIEE----ERFLDAAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLAVA 141 + + ++ + AA +G+ +V +L+ + + D G+ LA Sbjct: 90 VLLKNGAGVNATDVIGTAPLHLAAMWGHEEIVEVLLK--NGADARAQDKFGKTPEDLARD 147 Query: 142 NEHLEITELLLK 153 N + + L K Sbjct: 148 NGYESVARLARK 159 >6MWQ-A nrPDB Length = 493 Score = 161 bits (407), Expect = 1e-39, Method: Composition-based stats. Identities = 62/240 (25%), Positives = 97/240 (40%), Gaps = 42/240 (17%) Query: 91 STSLSIEEERFLDAAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLAVANEHLEITEL 150 + L ++ L+AA G VR ++ + +VN +D G L LA HLEI E+ Sbjct: 2 GSDL---GKKLLEAARAGQDDEVRILM--ANGADVNALDRFGLTPLHLAAQRGHLEIVEV 56 Query: 151 LLKKENLSRVGD-----ALLLAISKGYVRIVEAILNHPAFAEGKRLATSPSQSELQQDDF 205 LLK D L LA + G++ IVE +L + A D Sbjct: 57 LLKCGADVNAADLWGQTPLHLAATAGHLEIVEVLLKYGA-------------------DV 97 Query: 206 YAYDEDGTRFSHDVTPIILAAHCQEYEIVHTLLRKGARIERPHDYFCKCT-ECSQKQKHD 264 A D G TP+ L A EIV LL+ GA + D F K + S ++ Sbjct: 98 NALDLIGK------TPLHLTAIDGHLEIVEVLLKHGADV-NAQDKFGKTAFDISIDNGNE 150 Query: 265 SFSHSRSRINAYKGLASPAYLSLSSEDPVMTALELSNELAV-LANIEKEFKNDYRKLSMQ 323 + ++N L+ A+ ++ ++ A E + +A L +I E + R+ Q Sbjct: 151 DLAEILQKLN----LSDIAHRIVAPGKGILAADESTGSIAKRLQSIGTENTEENRRFYRQ 206 >6MHW-A nrPDB Length = 826 Score = 159 bits (401), Expect = 7e-39, Method: Composition-based stats. Identities = 31/156 (19%), Positives = 74/156 (47%), Gaps = 6/156 (3%) Query: 599 AIAVVLSFSRIAYILPANESFGPLQISLGRTV-KDIFKFMVIFIMVFVAFMIGMFNLYSY 657 +A+ L ++ + Y +S G + + + + D+ KF+ ++I+ + F + + +L Sbjct: 553 VLAMALGWANMLYYTRGFQSMGMYSVMIQKVILHDVLKFLFVYIVFLLGFGVALASLIEK 612 Query: 658 YI-GAKQNEAFTTVEESFKTLFWAIFGLSEVKSVVINYNHKFIENIGYVLYGVYNVTMVI 716 K ++ + ++ LF GL ++ I N K+ ++L Y + + Sbjct: 613 CPKDNKDCSSYGSFSDAVLELFKLTIGLGDL---NIQQNSKYPILFLFLLI-TYVILTFV 668 Query: 717 VLLNMLIAMINSSFQEIEDDADVEWKFARAKLWFSY 752 +LLNMLIA++ + + + +++ W+ RA+ + Sbjct: 669 LLLNMLIALMGETVENVSKESERIWRLQRARTILEF 704 Score = 36.7 bits (83), Expect = 0.050, Method: Composition-based stats. Identities = 27/139 (19%), Positives = 43/139 (30%), Gaps = 16/139 (11%) Query: 127 CVDYMGQNALQLAVANEH---LEITELLLKKENLSRVGDALLLAISKGYVRIVEAILNHP 183 G+ L A+ N + EI +LL + + + A + LN Sbjct: 164 TASDTGKTCLMKALLNINPNTKEIVRILLAFAEENDILGRFINAEYTEEAYEGQTALN-- 221 Query: 184 AFAEGKRLATSPSQSELQQDDFYAYDEDGTRFSHDV---------TPIILAAHCQEYEIV 234 A +R + D A+ + G F+ TP+ LAA + EIV Sbjct: 222 -IAIERRQGDIAALLIAAGADVNAHAK-GAFFNPKYQHEGFYFGETPLALAACTNQPEIV 279 Query: 235 HTLLRKGARIERPHDYFCK 253 L+ D Sbjct: 280 QLLMEHEQTDITSRDSRGN 298 Score = 35.2 bits (79), Expect = 0.13, Method: Composition-based stats. Identities = 25/122 (20%), Positives = 42/122 (34%), Gaps = 29/122 (23%) Query: 130 YMGQNALQLAVANEHLEITELLLKKEN------LSRVGDALLLAISKGYVRIVEAILNHP 183 Y G+ L LA EI +LL++ E SR + L Sbjct: 261 YFGETPLALAACTNQPEIVQLLMEHEQTDITSRDSRGNNILH------------------ 302 Query: 184 AFAEGKRLATSPSQSELQQDDFYAY-----DEDGTRFSHDVTPIILAAHCQEYEIVHTLL 238 A + + + D + + TR + +TP+ LAA + EI+ +L Sbjct: 303 ALVTVAEDFKTQNDFVKRMYDMILLRSGNWELETTRNNDGLTPLQLAAKMGKAEILKYIL 362 Query: 239 RK 240 + Sbjct: 363 SR 364 >5MIO-C nrPDB Length = 573 Score = 156 bits (393), Expect = 5e-38, Method: Composition-based stats. Identities = 52/183 (28%), Positives = 72/183 (39%), Gaps = 34/183 (18%) Query: 98 EERFLDAAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLAVANEHLEITELLLKKENL 157 ++ L+AA G VR ++ + +VN D G L LA HLEI E+LLK Sbjct: 411 GKKLLEAARAGQDDEVRVLM--ANGADVNATDASGLTPLHLAATYGHLEIVEVLLKHGAD 468 Query: 158 SRVGD-----ALLLAISKGYVRIVEAILNHPAFAEGKRLATSPSQSELQQDDFYAYDEDG 212 D L LA G++ IVE +L H A D A D G Sbjct: 469 VSASDLMGSTPLHLAALIGHLEIVEVLLKHGA-------------------DVNAVDTWG 509 Query: 213 TRFSHDVTPIILAAHCQEYEIVHTLLRKGARIERPHDYFCKCT-ECSQKQKHDSFSHSRS 271 TP+ LAA +IV LL+ GA + D F K + S + + Sbjct: 510 D------TPLRLAAVMGHLKIVEALLKHGADV-NAQDKFGKTAYDTSIDNGSEDLAEILQ 562 Query: 272 RIN 274 ++N Sbjct: 563 KLN 565 >6DVZ-A nrPDB Length = 791 Score = 152 bits (384), Expect = 6e-37, Method: Composition-based stats. Identities = 29/156 (18%), Positives = 72/156 (46%), Gaps = 6/156 (3%) Query: 599 AIAVVLSFSRIAYILPANESFGPLQISLGRTV-KDIFKFMVIFIMVFVAFMIGMFNLYSY 657 +A+ L ++ + +S G + + + + D+ KF+ ++I+ + F + + +L Sbjct: 552 VLAMALGWANMLAYTRGFQSMGMYSVMIQKVILHDVLKFLFVYILFLLGFGVALASLIEK 611 Query: 658 Y-IGAKQNEAFTTVEESFKTLFWAIFGLSEVKSVVINYNHKFIENIGYVLYGVYNVTMVI 716 K ++ + ++ LF GL ++ I N + ++L Y + + Sbjct: 612 CSKDKKDCSSYGSFSDAVLELFKLTIGLGDL---NIQQNSTYPILFLFLLI-TYVILTFV 667 Query: 717 VLLNMLIAMINSSFQEIEDDADVEWKFARAKLWFSY 752 +LLNMLIA++ + + + +++ W+ RA+ + Sbjct: 668 LLLNMLIALMGETVENVSKESERIWRLQRARTILEF 703 Score = 39.8 bits (91), Expect = 0.006, Method: Composition-based stats. Identities = 34/218 (15%), Positives = 64/218 (29%), Gaps = 55/218 (25%) Query: 76 RRLANRGPAYMFNDHSTSLSIEEE----RFLDAAEYGNIPVVRKMLEECHSLNV------ 125 RR P ++ H + S + + L +VR +L ++ Sbjct: 148 RRRGLDVPDFLM--HKLTASDTGKTCLMKALLNINPNTKEIVRILLAFAEENDILDRFIN 205 Query: 126 ---NCVDYMGQNALQLAVANEHLEITELLLKKENLSRVG-------------------DA 163 Y GQ AL +A+ +IT +L+ Sbjct: 206 AEYTEEAYEGQTALNIAIERRQGDITAVLIAAGADVNAHAKGVFFNPKYQHEGFYFGETP 265 Query: 164 LLLAISKGYVRIVEAILNHP----------------AFAEGKRLATSPSQSELQQDDFYA 207 L LA IV+ ++ + A + + + D Sbjct: 266 LALAACTNQPEIVQLLMENEQTDITSQDSRGNNILHALVTVAEDFKTQNDFVKRMYDMIL 325 Query: 208 Y-----DEDGTRFSHDVTPIILAAHCQEYEIVHTLLRK 240 + + R + +TP+ LAA + EI+ +L + Sbjct: 326 LRSGNWELETMRNNDGLTPLQLAAKMGKAEILKYILSR 363 Score = 39.0 bits (89), Expect = 0.009, Method: Composition-based stats. Identities = 34/176 (19%), Positives = 57/176 (32%), Gaps = 30/176 (17%) Query: 104 AAEYGNIPVVRKMLEECH-------SLNVNC-------VDYMGQNALQLAVANEH---LE 146 A G + +R++L++ L+V G+ L A+ N + E Sbjct: 126 AVSEGCVEELRELLQDLQDLCRRRRGLDVPDFLMHKLTASDTGKTCLMKALLNINPNTKE 185 Query: 147 ITELLLKKENLSRVGDALLLAISKGYVRIVEAILNHPAFAEGKRLATSPSQSELQQDDFY 206 I +LL + + D + A + LN A +R + D Sbjct: 186 IVRILLAFAEENDILDRFINAEYTEEAYEGQTALN---IAIERRQGDITAVLIAAGADVN 242 Query: 207 AYDEDGTRFSHDV---------TPIILAAHCQEYEIVHTLLRKGARIERPHDYFCK 253 A+ + G F+ TP+ LAA + EIV L+ D Sbjct: 243 AHAK-GVFFNPKYQHEGFYFGETPLALAACTNQPEIVQLLMENEQTDITSQDSRGN 297 >5MKE-A nrPDB Length = 968 Score = 146 bits (368), Expect = 4e-35, Method: Composition-based stats. Identities = 48/221 (21%), Positives = 86/221 (38%), Gaps = 36/221 (16%) Query: 520 YLFELWNMLDFGMLAIFAASFIARFMAFWHASKAQSIIDANDTLKDLTKVTLGDNVKYYN 579 Y WN LD ++ + + + L+ L N ++ Sbjct: 502 YFRSFWNCLDVVIVVLSVVAIGINI---------YRTSNVEVLLQFLEDQNTFPNFEHLA 552 Query: 580 LARIKWDPTDPQIISEGLYAIAVVLSFSRIAYILPANESFGPLQISLGRTVKDIFKFMVI 639 W QI + A+ V + ++ + N + L ++ R KD+F F ++ Sbjct: 553 Y----W-----QIQFNNIAAVTVFFVWIKLFKFINFNRTMSQLSTTMSRCAKDLFGFAIM 603 Query: 640 FIMVFVAFMIGMFNLYSYYIGAKQNEAFTTVEESFKTLFWAIFGLSEVKSVVINYNHKFI 699 F ++F+A+ +Y + Q + F+T +E T F I G + N I Sbjct: 604 FFIIFLAYA-----QLAYLVFGTQVDDFSTFQECIFTQFRIILG---------DINFAEI 649 Query: 700 ENIGYVLYGVY----NVTMVIVLLNMLIAMINSSFQEIEDD 736 E VL +Y M +LLNM +A+IN ++ E++ D Sbjct: 650 EEANRVLGPIYFTTFVFFMFFILLNMFLAIINDTYSEVKSD 690 >5T4D-A nrPDB Length = 510 Score = 146 bits (367), Expect = 6e-35, Method: Composition-based stats. Identities = 48/221 (21%), Positives = 86/221 (38%), Gaps = 36/221 (16%) Query: 520 YLFELWNMLDFGMLAIFAASFIARFMAFWHASKAQSIIDANDTLKDLTKVTLGDNVKYYN 579 Y WN LD ++ + + + L+ L N ++ Sbjct: 310 YFRSFWNCLDVVIVVLSVVAIGINI---------YRTSNVEVLLQFLEDQNTFPNFEHLA 360 Query: 580 LARIKWDPTDPQIISEGLYAIAVVLSFSRIAYILPANESFGPLQISLGRTVKDIFKFMVI 639 W QI + A+ V + ++ + N + L ++ R KD+F F ++ Sbjct: 361 Y----W-----QIQFNNIAAVTVFFVWIKLFKFINFNRTMSQLSTTMSRCAKDLFGFAIM 411 Query: 640 FIMVFVAFMIGMFNLYSYYIGAKQNEAFTTVEESFKTLFWAIFGLSEVKSVVINYNHKFI 699 F ++F+A+ +Y + Q + F+T +E T F I G + N I Sbjct: 412 FFIIFLAYA-----QLAYLVFGTQVDDFSTFQECIFTQFRIILG---------DINFAEI 457 Query: 700 ENIGYVLYGVY----NVTMVIVLLNMLIAMINSSFQEIEDD 736 E VL +Y M +LLNM +A+IN ++ E++ D Sbjct: 458 EEANRVLGPIYFTTFVFFMFFILLNMFLAIINDTYSEVKSD 498 >6D1W-A nrPDB Length = 740 Score = 142 bits (357), Expect = 8e-34, Method: Composition-based stats. Identities = 47/221 (21%), Positives = 85/221 (38%), Gaps = 36/221 (16%) Query: 520 YLFELWNMLDFGMLAIFAASFIARFMAFWHASKAQSIIDANDTLKDLTKVTLGDNVKYYN 579 Y WN LD ++ + + + L+ L N ++ Sbjct: 450 YFRSFWNCLDVVIVVLSVVAIGINI---------YRTSNVEVLLQFLEDQNTFPNFEHLA 500 Query: 580 LARIKWDPTDPQIISEGLYAIAVVLSFSRIAYILPANESFGPLQISLGRTVKDIFKFMVI 639 W QI + A+ V + ++ + N + L ++ R KD+F F ++ Sbjct: 501 Y----W-----QIQFNNIAAVTVFFVWIKLFKFINFNRTMSQLSTTMSRCAKDLFGFAIM 551 Query: 640 FIMVFVAFMIGMFNLYSYYIGAKQNEAFTTVEESFKTLFWAIFGLSEVKSVVINYNHKFI 699 ++F+A+ +Y + Q + F+T +E T F I G + N I Sbjct: 552 PFIIFLAYA-----QLAYLVFGTQVDDFSTFQECIFTQFRIILG---------DINFAEI 597 Query: 700 ENIGYVLYGVY----NVTMVIVLLNMLIAMINSSFQEIEDD 736 E VL +Y M +LLNM +A+IN ++ E++ D Sbjct: 598 EEANRVLGPIYFTTFVFFMFFILLNMFLAIINDTYSEVKSD 638 >6DU8-A nrPDB Length = 805 Score = 139 bits (350), Expect = 5e-33, Method: Composition-based stats. Identities = 50/247 (20%), Positives = 100/247 (40%), Gaps = 36/247 (14%) Query: 494 EMLIISWVIGMIWAECKEIWTQGPKEYLFELWNMLDFGMLAIFAASFIARFMAFWHASKA 553 E++ ++ + E E+ + YL +WN+LD ++ + + ++ Sbjct: 356 EVIFCVFIFYYVVEEILELHIHRLR-YLSSIWNILDLVVILLSIVAVGFHIFRTLEVNRL 414 Query: 554 QSIIDANDTLKDLTKVTLGDNVKYYNLARIKWDPTDPQIISEGLYAIAVVLSFSRIAYIL 613 K L + + ++ W Q + A+ + ++ +I + Sbjct: 415 MG--------KLLQQPNTYADFEFLAF----W-----QTQYNNMNAVNLFFAWIKIFKYI 457 Query: 614 PANESFGPLQISLGRTVKDIFKFMVIFIMVFVAFMIGMFNLYSYYIGAKQNEAFTTVEES 673 N++ L +L R KDI F V+F +VF A+ Y + Q E F+T + Sbjct: 458 SFNKTMTQLSSTLARCAKDILGFAVMFFIVFFAYA-----QLGYLLFGTQVENFSTFIKC 512 Query: 674 FKTLFWAIFGLSEVKSVVINYNHKFIENIGYVLYGV----YNVTMVIVLLNMLIAMINSS 729 T F I G ++++ I+N +L Y + VLLNM +A+IN + Sbjct: 513 IFTQFRIILG---------DFDYNAIDNANRILGPAYFVTYVFFVFFVLLNMFLAIINDT 563 Query: 730 FQEIEDD 736 + E++++ Sbjct: 564 YSEVKEE 570 >5Z1W-A nrPDB Length = 566 Score = 139 bits (350), Expect = 6e-33, Method: Composition-based stats. Identities = 51/248 (20%), Positives = 100/248 (40%), Gaps = 38/248 (15%) Query: 494 EMLIISWVIGMIWAECKEIWTQGPKEYLFELWNMLDFGMLAIFAASFIARFMAFWHASKA 553 E++ ++ + E EI + YL +WN+LD ++ + + ++ Sbjct: 293 EVVFCVFIFYYVVEEILEIHLHRLR-YLSSVWNILDLVVILLSIVAVGFHIFRTLEVNRL 351 Query: 554 Q-SIIDANDTLKDLTKVTLGDNVKYYNLARIKWDPTDPQIISEGLYAIAVVLSFSRIAYI 612 ++ DT D + W Q + A+ + ++ +I Sbjct: 352 MGKLLQQPDTYADFEFLAF-------------W-----QTQYNNMNAVNLFFAWIKIFKY 393 Query: 613 LPANESFGPLQISLGRTVKDIFKFMVIFIMVFVAFMIGMFNLYSYYIGAKQNEAFTTVEE 672 + N++ L +L R KDI F ++F +VF A+ Y + Q E F+T + Sbjct: 394 ISFNKTMTQLSSTLARCAKDILGFAIMFFIVFFAYA-----QLGYLLFGTQVENFSTFVK 448 Query: 673 SFKTLFWAIFGLSEVKSVVINYNHKFIENIGYVLYG----VYNVTMVIVLLNMLIAMINS 728 T F I G ++++ I+N +L Y + VLLNM +A+IN Sbjct: 449 CIFTQFRIILG---------DFDYNAIDNANRILGPVYFVTYVFFVFFVLLNMFLAIIND 499 Query: 729 SFQEIEDD 736 ++ E++++ Sbjct: 500 TYSEVKEE 507 >4OAU-C nrPDB Length = 699 Score = 117 bits (294), Expect = 2e-26, Method: Composition-based stats. Identities = 30/105 (28%), Positives = 56/105 (53%), Gaps = 5/105 (4%) Query: 84 AYMFNDHSTSLSIEEER----FLDAAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLA 139 ++ DH +++ ER + A E ++ +V+++LE+ H + +N D G+ AL LA Sbjct: 202 THLLLDHGADVNVRGERGKTPLILAVEKKHLGLVQRLLEQEH-IEINDTDSDGKTALLLA 260 Query: 140 VANEHLEITELLLKKENLSRVGDALLLAISKGYVRIVEAILNHPA 184 V + +I ELL K+ + GD ++ A +V+ +L+H A Sbjct: 261 VELKLKKIAELLCKRGASTDCGDLVMTARRNYDHSLVKVLLSHGA 305 Score = 70.2 bits (170), Expect = 4e-12, Method: Composition-based stats. Identities = 41/155 (26%), Positives = 69/155 (44%), Gaps = 34/155 (21%) Query: 100 RFLDAAEYGNIPVVRKMLEECHSLNVNCVDYMGQNAL---QLAVANEHLE-ITELLLKKE 155 +DAAE G++ V++ +L+E +VN D MG+NAL L+ + +E IT LLL Sbjct: 151 ALMDAAEKGHVEVLKILLDEM-GADVNACDNMGRNALIHALLSSDDSDVEAITHLLLDHG 209 Query: 156 NLSRV-----GDALLLAISKGYVRIVEAILNHPAFAEGKRLATSPSQSELQQDDFYAYDE 210 V L+LA+ K ++ +V+ +L E + + D Sbjct: 210 ADVNVRGERGKTPLILAVEKKHLGLVQRLL------------------EQEHIEINDTDS 251 Query: 211 DGTRFSHDVTPIILAAHCQEYEIVHTLLRKGARIE 245 DG T ++LA + +I L ++GA + Sbjct: 252 DGK------TALLLAVELKLKKIAELLCKRGASTD 280 Score = 61.3 bits (147), Expect = 2e-09, Method: Composition-based stats. Identities = 31/151 (20%), Positives = 55/151 (36%), Gaps = 33/151 (21%) Query: 101 FLDAAEYGNIPVVRKMLEECHSLNVNCVDYMG-QNALQLAVANEHLEITELLLKKENL-- 157 + A + ++ +V+++LE NVN + G L AV +I ELLL+ Sbjct: 9 LIKAVQNEDVDLVQQLLEG--GANVNFQEEEGGWTPLHNAVQMSREDIVELLLRHGADPV 66 Query: 158 ---SRVGDALLLAISKGYVRIVEAILNHPAFAEGKRLATSPSQSELQQDDFYAYDEDGTR 214 +LA G V++++ L+ A D D G Sbjct: 67 LRKKNGATPFILAAIAGSVKLLKLFLSKGA-------------------DVNECDFYG-- 105 Query: 215 FSHDVTPIILAAHCQEYEIVHTLLRKGARIE 245 T + AA + + + L ++GA + Sbjct: 106 ----FTAFMEAAVYGKVKALKFLYKRGANVN 132 Score = 61.0 bits (146), Expect = 2e-09, Method: Composition-based stats. Identities = 35/198 (17%), Positives = 67/198 (33%), Gaps = 43/198 (21%) Query: 86 MFNDHSTSLSIEEER----FLDAAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLAVA 141 + H + ++ F+ AA G++ +++ L +VN D+ G A A Sbjct: 57 LLLRHGADPVLRKKNGATPFILAAIAGSVKLLKLFL--SKGADVNECDFYGFTAFMEAAV 114 Query: 142 NEHLEITELLLKKENLSR---------------VGDALLLAISKGYVRIVEAILNHPAFA 186 ++ + L K+ AL+ A KG+V +++ +L Sbjct: 115 YGKVKALKFLYKRGANVNLRRKTKEDQERLRKGGATALMDAAEKGHVEVLKILL------ 168 Query: 187 EGKRLATSPSQSELQQDDFYAYDEDGTRFSHDVTPIILAAHCQEYE-IVHTLLRKGARIE 245 + D A D G +L++ + E I H LL GA + Sbjct: 169 ------------DEMGADVNACDNMGRNALIHA---LLSSDDSDVEAITHLLLDHGADVN 213 Query: 246 RPHDYFCKCTECSQKQKH 263 + + ++KH Sbjct: 214 VRGERGKTPLILAVEKKH 231 Score = 47.1 bits (110), Expect = 3e-05, Method: Composition-based stats. Identities = 28/122 (22%), Positives = 41/122 (33%), Gaps = 31/122 (25%) Query: 136 LQLAVANEHLEITELLLKKENLSR------VGDALLLAISKGYVRIVEAILNHPAFAEGK 189 L AV NE +++ + LL+ L A+ IVE +L H A Sbjct: 9 LIKAVQNEDVDLVQQLLEGGANVNFQEEEGGWTPLHNAVQMSREDIVELLLRHGA----- 63 Query: 190 RLATSPSQSELQQDDFYAYDEDGTRFSHDVTPIILAAHCQEYEIVHTLLRKGARIERPHD 249 D ++G TP ILAA +++ L KGA + Sbjct: 64 --------------DPVLRKKNGA------TPFILAAIAGSVKLLKLFLSKGADVNECDF 103 Query: 250 YF 251 Y Sbjct: 104 YG 105 >5CBO-A nrPDB Length = 176 Score = 116 bits (290), Expect = 5e-26, Method: Composition-based stats. Identities = 38/150 (25%), Positives = 56/150 (37%), Gaps = 32/150 (21%) Query: 98 EERFLDAAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLAVANEHLEITELLLKKENL 157 ++ L+AA G VR ++ + +VN +D G L LA H EI E+LLK Sbjct: 4 GKKLLEAAHAGQDDEVRILM--ANGADVNAMDNFGVTPLHLAAYWGHFEIVEVLLKYGAD 61 Query: 158 SRVGD-----ALLLAISKGYVRIVEAILNHPAFAEGKRLATSPSQSELQQDDFYAYDEDG 212 D L LA GY+ IVE +L + A D A D+ G Sbjct: 62 VNASDATGDTPLHLAAKWGYLGIVEVLLKYGA-------------------DVNAQDKFG 102 Query: 213 TRFSHDVTPIILAAHCQEYEIVHTLLRKGA 242 T ++ ++ L + A Sbjct: 103 K------TAFDISIDNGNEDLAEILCKNKA 126 Score = 60.2 bits (144), Expect = 4e-09, Method: Composition-based stats. Identities = 26/106 (24%), Positives = 37/106 (34%), Gaps = 25/106 (23%) Query: 158 SRVGDALLLAISKGYVRIVEAILNHPAFAEGKRLATSPSQSELQQDDFYAYDEDGTRFSH 217 S +G LL A G V ++ + A D A D G Sbjct: 1 SDLGKKLLEAAHAGQDDEVRILMANGA-------------------DVNAMDNFG----- 36 Query: 218 DVTPIILAAHCQEYEIVHTLLRKGARIERPHDYFCKCTECSQKQKH 263 VTP+ LAA+ +EIV LL+ GA + + K + Sbjct: 37 -VTPLHLAAYWGHFEIVEVLLKYGADVNASDATGDTPLHLAAKWGY 81 Score = 50.9 bits (120), Expect = 3e-06, Method: Composition-based stats. Identities = 17/102 (16%), Positives = 45/102 (44%), Gaps = 12/102 (11%) Query: 86 MFNDHSTSLSIEEER----FLDAAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLAVA 141 + + ++ + AA++G + +V +L+ + +VN D G+ A +++ Sbjct: 54 VLLKYGADVNASDATGDTPLHLAAKWGYLGIVEVLLK--YGADVNAQDKFGKTAFDISID 111 Query: 142 NEHLEITELLLKKENLSRVGDALLL------AISKGYVRIVE 177 N + ++ E+L K + +L A G+++ ++ Sbjct: 112 NGNEDLAEILCKNKAQQAAFYCILHMPNLNEAQRNGFIQSLK 153 >6BPQ-A nrPDB Length = 950 Score = 113 bits (282), Expect = 4e-25, Method: Composition-based stats. Identities = 91/497 (18%), Positives = 174/497 (35%), Gaps = 119/497 (23%) Query: 294 MTALELSNELAVLANIEKEFKNDYR--KLSMQCKDFVVGLLDLCRNTEE--VEAILNGDA 349 + AL S L +A ++ + +L+ + + V L C + +E E +L Sbjct: 464 LAALGASKLLKSMAKVKNDINAAGESEELANEYETRAVELFTECYSNDEDLAEQLLTYSC 523 Query: 350 ETRQPGDFGRPNLSRLKLAIKYEVKKFVAHPNCQQQLLSIWYENLSGLRQQTMAVKFLVV 409 E +G N L+LA++ ++F+A P Q L WY +S + T K ++ Sbjct: 524 EA-----WGGSNC--LELAVEARDQQFIAQPGVQNFLSKQWYGEIS---RDTKNWKIILC 573 Query: 410 LAVAIGLPFLALIYWCAPCSKMGK----------ILRGPFMKFVAHAASFTIFLGLLVMN 459 L P + + + K PF+ F + + FL L Sbjct: 574 LFF---FPLIGCGFISFRKKPVEKTKKLFLYYVSFFTSPFVVFSWNVIFYIAFLLL---- 626 Query: 460 AADRFEGTKLLPNETSTDNARQLFRMKTSCFSWMEMLIISWVIGMIWAECKEIWTQGPKE 519 A L + +E+++ V ++ E ++ + G K Sbjct: 627 ------------------FAYVLLMDFQKEPTALEIILYVLVFILLCDEVRQWYMNGSK- 667 Query: 520 YLFELWNMLDFGMLAIFAASFIARFMAFWHASKAQSIIDANDTLKDLTKVTLGDNVKYYN 579 Y +LWN++D + F A + R H+ ++ Sbjct: 668 YFSDLWNVMDTLAIFYFIAGIVFR----LHSDESSWYSGRV------------------- 704 Query: 580 LARIKWDPTDPQIISEGLYAIAVVLSFSRIAYILPANESFGPLQISLGRTVKDIFKFMVI 639 ++ + ++ R+ +I + + GP I L R + D+F F+ + Sbjct: 705 -----------------IFCLDYIVFTLRLIHIFTVSRNLGPKIIMLQRMMIDVFFFLFL 747 Query: 640 FIMVFVAFMIGMFNLYSYYIGAKQNEAFT-TVEESFKTLFWAIFGL--SEVKSVVINYNH 696 F + VAF + + K + + A+FG ++ N++H Sbjct: 748 FAVWMVAFGVARQGILR-----KNEHRWEWIFRSVIYEPYLAMFGQYPDDIDGTTYNFDH 802 Query: 697 ---------------------KFIENIGYVLYGVYNVTMVIVLLNMLIAMINSSFQEIED 735 +F E I L +Y ++ I+L+N+L+AM + +++ Sbjct: 803 CTFSGNESKPLCVELDANNQPRFPEWITIPLVCIYMLSTNILLVNLLVAMFGYTVGSVQE 862 Query: 736 DADVEWKFARAKLWFSY 752 + D WKF R L Y Sbjct: 863 NNDQVWKFQRFFLVQEY 879 >6BBJ-A nrPDB Length = 868 Score = 105 bits (262), Expect = 9e-23, Method: Composition-based stats. Identities = 39/235 (16%), Positives = 83/235 (35%), Gaps = 39/235 (16%) Query: 596 GLYAIAVVLSFSRIAYILPANESFGPLQISLGRTV-KDIFKFMVIFIMVFVAFMIGMFNL 654 + A+VL + Y + G I L + + KD+F+F++++++ + + + +L Sbjct: 572 AVMVFALVLGWMNALYFTRGLKLTGTYSIMLQKILFKDLFRFLLVYLLFMIGYASALVSL 631 Query: 655 YSYY---------------IGAKQNEAFTTVEESFKTLFWAIFGLSEVKSVVINYNHKFI 699 + +T + LF G+ +++ + N Sbjct: 632 LNPCTSQESCIETSSNCTVPEYPSCRDSSTFSKFLLDLFKLTIGMGDLEMI----NSAKY 687 Query: 700 ENIGYVLYGVYNVTMVIVLLNMLIAMINSSFQEIEDDADVEWKFARAKLWFSY------- 752 + +L Y + ++LLNMLIA++ + ++ ++ WK A Sbjct: 688 PAVFIILLVTYIILTFVLLLNMLIALMGETVGQVSKESKQIWKLQWATTILDIERSFPVC 747 Query: 753 ----FEEGRTLPVPFNLVPSPKSLLYLLLKFKKW--------MCELIQGQKQGFQ 795 F G + V NL +P + W + G+ G+Q Sbjct: 748 MRKAFRSGEMVTVGKNLDGTPDRRWCFRVDEVNWSHWNQNLGIINEDPGRNDGYQ 802 Score = 34.4 bits (77), Expect = 0.22, Method: Composition-based stats. Identities = 39/176 (22%), Positives = 58/176 (32%), Gaps = 16/176 (9%) Query: 51 GYYPSFRGNENRLTHRRQTILREKGRRLANRGPAYMFNDHSTSLSIEEERFLDAAEY-GN 109 G+ P + RLT RE A M + + +I +D AE GN Sbjct: 164 GFLPFLLAQKKRLTDEE---FREASTGKTCLTKALMNLNGGKNDTI--PMLIDIAEKTGN 218 Query: 110 IPVVRKMLEECHSLNVNCVDYMGQNALQLAVANEHLEITELLLKKENLSRV---GDALLL 166 L E + V Y GQ AL +A+ ELL++K G Sbjct: 219 -------LREFINSPFRDVYYRGQTALHIAIERRCKHYVELLVEKGADVHAQARGRFFQP 271 Query: 167 AISKGYVRIVEAILNHPAFAEGKRLATSPSQSELQQDDFYAYDEDGTRFSHDVTPI 222 GY E L+ A + +++ ++ D D G H + I Sbjct: 272 KDEGGYFYFGELPLSLAACTNQPDIVHYLTENAHKKADIRRQDSRGNTVLHALVAI 327 >6C8G-A nrPDB Length = 675 Score = 105 bits (261), Expect = 1e-22, Method: Composition-based stats. Identities = 36/214 (16%), Positives = 77/214 (35%), Gaps = 31/214 (14%) Query: 596 GLYAIAVVLSFSRIAYILPANESFGPLQISLGRTV-KDIFKFMVIFIMVFVAFMIGMFNL 654 + A+VL + Y + G I L + + KD+F+F++++++ + + + +L Sbjct: 441 AVMVFALVLGWMNALYFTRGLKLTGTYSIMLQKILFKDLFRFLLVYLLFMIGYASALVSL 500 Query: 655 YSYY---------------IGAKQNEAFTTVEESFKTLFWAIFGLSEVKSVVINYNHKFI 699 + +T + LF G+ +++ + N Sbjct: 501 LNPCTSQESCIETSSQCTVPEYPSCRDSSTFSKFLLDLFKLTIGMGDLEMI----NSAKY 556 Query: 700 ENIGYVLYGVYNVTMVIVLLNMLIAMINSSFQEIEDDADVEWKFARAKLWFSY------- 752 + +L Y + ++LLNMLIA++ + ++ ++ WK A Sbjct: 557 PAVFIILLVTYIILTFVLLLNMLIALMGETVGQVSKESKQIWKLQWATTILDIERSFPVC 616 Query: 753 ----FEEGRTLPVPFNLVPSPKSLLYLLLKFKKW 782 F G + V NL +P + W Sbjct: 617 MRKAFRSGEMVTVGKNLDGTPDRRWCFRVDEVNW 650 Score = 34.4 bits (77), Expect = 0.24, Method: Composition-based stats. Identities = 39/176 (22%), Positives = 58/176 (32%), Gaps = 16/176 (9%) Query: 51 GYYPSFRGNENRLTHRRQTILREKGRRLANRGPAYMFNDHSTSLSIEEERFLDAAEY-GN 109 G+ P + RLT RE A M + + +I +D AE GN Sbjct: 33 GFLPFLLAQKKRLTDEE---FREASTGKTCLTKALMNLNGGKNDTI--PMLIDIAEKTGN 87 Query: 110 IPVVRKMLEECHSLNVNCVDYMGQNALQLAVANEHLEITELLLKKENLSRV---GDALLL 166 L E + V Y GQ AL +A+ ELL++K G Sbjct: 88 -------LREFINSPFRDVYYRGQTALHIAIERRCKHYVELLVEKGADVHAQARGRFFQP 140 Query: 167 AISKGYVRIVEAILNHPAFAEGKRLATSPSQSELQQDDFYAYDEDGTRFSHDVTPI 222 GY E L+ A + +++ ++ D D G H + I Sbjct: 141 KDEGGYFYFGELPLSLAACTNQPDIVHYLTENAHKKADIRRQDSRGNTVLHALVAI 196 >5IRX-A nrPDB Length = 636 Score = 103 bits (256), Expect = 4e-22, Method: Composition-based stats. Identities = 33/155 (21%), Positives = 72/155 (46%), Gaps = 14/155 (9%) Query: 593 ISEGLYAIAVVLSFSRIAYILPANESFGPLQISLGRTV-KDIFKFMVIFIMVFVAFMIGM 651 ++ ++++A+ ++ + Y + G + + + + +D+ +FM ++++ F + Sbjct: 433 VASMVFSLAM--GWTNMLYYTRGFQQMGIYAVMIEKMILRDLCRFMFVYLVFLFGFSTAV 490 Query: 652 FNLYSYYIGAKQNEAFTTVEESFKTLFWAIFGLSEVKSVVINYNHKFIENIGYVLYGVYN 711 L K N ++T LF G+ +++ NY+ K + I L Y Sbjct: 491 VTLIE---DGKYNSLYST----CLELFKFTIGMGDLEFTE-NYDFKAVFII---LLLAYV 539 Query: 712 VTMVIVLLNMLIAMINSSFQEIEDDADVEWKFARA 746 + I+LLNMLIA++ + +I ++ WK RA Sbjct: 540 ILTYILLLNMLIALMGETVNKIAQESKNIWKLQRA 574 Score = 42.1 bits (97), Expect = 0.001, Method: Composition-based stats. Identities = 37/214 (17%), Positives = 66/214 (30%), Gaps = 55/214 (25%) Query: 108 GNIPVVRKMLEECHSLN-----VNC--VD--YMGQNALQLAVANEHLEITELLLKKENLS 158 G + +L+ + VN D Y GQ AL +A+ ++ + LL++ Sbjct: 63 GQNDTIALLLDVARKTDSLKQFVNASYTDSYYKGQTALHIAIERRNMTLVTLLVENGADV 122 Query: 159 RV---GD----------------ALLLAISKGYVRIVEAILNH---PAFAEGKRLATSPS 196 + GD L LA + IV+ +L + PA + + Sbjct: 123 QAAANGDFFKKTKGRPGFYFGELPLSLAACTNQLAIVKFLLQNSWQPADISARDSVGNTV 182 Query: 197 QSELQQDDFYAYDED-------------GTRFSHD-----------VTPIILAAHCQEYE 232 L + D G + +TP+ LAA + Sbjct: 183 LHALVEVADNTVDNTKFVTSMYNEILILGAKLHPTLKLEEITNRKGLTPLALAASSGKIG 242 Query: 233 IVHTLLRKGARIERPHDYFCKCTECSQKQKHDSF 266 ++ +L++ K TE + H S Sbjct: 243 VLAYILQREIHEPECRHLSRKFTEWAYGPVHSSL 276 >4Z68-A nrPDB Length = 155 Score = 93.3 bits (230), Expect = 4e-19, Method: Composition-based stats. Identities = 39/177 (22%), Positives = 63/177 (35%), Gaps = 35/177 (19%) Query: 95 SIEEERFLDAAEYGNIPVVRKMLEECHSLNVNCVDYMGQ--NALQLAVANEHLEITELLL 152 S + + L+AA+ G++ V+K+ C +VNC D G+ L A + + E LL Sbjct: 1 SEADRQLLEAAKAGDVETVKKL---CTVQSVNCRDIEGRQSTPLHFAAGYNRVSVVEYLL 57 Query: 153 KKENLSRVGD-----ALLLAISKGYVRIVEAILNHPAFAEGKRLATSPSQSELQQDDFYA 207 + D L A S G+ + E ++ H A Sbjct: 58 QHGADVHAKDKGGLVPLHNACSYGHYEVAELLVKHGAV-------------------VNV 98 Query: 208 YDEDGTRFSHDVTPIILAAHCQEYEIVHTLLRKGARIERPHDYFCKCTECSQKQKHD 264 D TP+ AA +YEI LL+ GA + + + + D Sbjct: 99 ADLW------KFTPLHEAAAKGKYEICKLLLQHGADPTKKNRDGNTPLDLVKDGDTD 149 Score = 71.7 bits (174), Expect = 1e-12, Method: Composition-based stats. Identities = 31/111 (27%), Positives = 46/111 (41%), Gaps = 7/111 (6%) Query: 104 AAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLAVANEHLEITELLLKKENLSRVGD- 162 AA Y + VV +L+ H +V+ D G L A + H E+ ELL+K + V D Sbjct: 44 AAGYNRVSVVEYLLQ--HGADVHAKDKGGLVPLHNACSYGHYEVAELLVKHGAVVNVADL 101 Query: 163 ----ALLLAISKGYVRIVEAILNHPAFAEGKRLATSPSQSELQQDDFYAYD 209 L A +KG I + +L H A K + ++ D D Sbjct: 102 WKFTPLHEAAAKGKYEICKLLLQHGADPTKKNRDGNTPLDLVKDGDTDIQD 152 Score = 38.2 bits (87), Expect = 0.015, Method: Composition-based stats. Identities = 10/48 (20%), Positives = 16/48 (33%) Query: 220 TPIILAAHCQEYEIVHTLLRKGARIERPHDYFCKCTECSQKQKHDSFS 267 TP+ AA +V LL+ GA + + H + Sbjct: 39 TPLHFAAGYNRVSVVEYLLQHGADVHAKDKGGLVPLHNACSYGHYEVA 86 >4O1O-A nrPDB Length = 717 Score = 89.8 bits (221), Expect = 5e-18, Method: Composition-based stats. Identities = 31/133 (23%), Positives = 57/133 (42%), Gaps = 8/133 (6%) Query: 73 EKGRRLANRGPAYMFNDHSTSLSIEEE----RFLDAAEYGNIPVVRKMLEECHSLNVNCV 128 + G+ A + DH +++ E + A E N+ +V+ +LE+ + VN Sbjct: 197 DDGKAKAI---TRLLLDHGADVNVRGEGSKTPLILAVERKNLDLVQMLLEQEQ-IEVNDT 252 Query: 129 DYMGQNALQLAVANEHLEITELLLKKENLSRVGDALLLAISKGYVRIVEAILNHPAFAEG 188 D G+ AL LAV EI +LL + + GD + +A +V+ + H A + Sbjct: 253 DREGKTALLLAVELRLEEIAKLLCHRGASTNCGDLVAIARRNYDSDLVKFLRLHKAGEDF 312 Query: 189 KRLATSPSQSELQ 201 + A + + Sbjct: 313 RPPAENWKPQSSR 325 Score = 64.0 bits (154), Expect = 3e-10, Method: Composition-based stats. Identities = 45/208 (21%), Positives = 74/208 (35%), Gaps = 60/208 (28%) Query: 75 GRRLANRGPAYMFNDHSTSLSIEEE--------------RFLDAAEYGNIPVVRKMLEEC 120 GR A R ++ +++ + +DAAE G++ VV +L Sbjct: 119 GRVEALR----FLYENGADVNMHRKTKQDQERIRKGGATALMDAAEKGHVGVVTILL-HA 173 Query: 121 HSLNVNCVDYMGQNALQLAVAN----EHLEITELLLKKENLSRV-----GDALLLAISKG 171 V+ D MG+NAL A+ N + IT LLL V L+LA+ + Sbjct: 174 MKAEVDARDNMGRNALVYALLNPDDGKAKAITRLLLDHGADVNVRGEGSKTPLILAVERK 233 Query: 172 YVRIVEAILNHPAFAEGKRLATSPSQSELQQDDFYAYDEDGTRFSHDVTPIILAAHCQEY 231 + +V+ +L E +Q + D +G T ++LA + Sbjct: 234 NLDLVQMLL------------------EQEQIEVNDTDREGK------TALLLAVELRLE 269 Query: 232 EIVHTLLRKGARIERPHDYFCKCTECSQ 259 EI L +GA C + Sbjct: 270 EIAKLLCHRGAST--------NCGDLVA 289 Score = 57.5 bits (137), Expect = 3e-08, Method: Composition-based stats. Identities = 32/153 (20%), Positives = 53/153 (34%), Gaps = 31/153 (20%) Query: 98 EERFLDAAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLAVANEHLEITELLLKKENL 157 EE A + +I VR++LE N + G + L AV + ++ LLLK Sbjct: 9 EEMLTQAVQEADIEQVRQLLERGADANFQE-EEWGWSPLHSAVQMDSEDLVALLLKHGAD 67 Query: 158 -----SRVGDALLLAISKGYVRIVEAILNHPAFAEGKRLATSPSQSELQQDDFYAYDEDG 212 ++A G VR+++ +L + +D D +G Sbjct: 68 PCLRKRNGATPFIIAGITGNVRLLQLLLPN-------------------VEDVNECDVNG 108 Query: 213 TRFSHDVTPIILAAHCQEYEIVHTLLRKGARIE 245 T + AA E + L GA + Sbjct: 109 ------FTAFMEAAVYGRVEALRFLYENGADVN 135 >5GP7-A nrPDB Length = 169 Score = 89.1 bits (219), Expect = 8e-18, Method: Composition-based stats. Identities = 40/193 (20%), Positives = 63/193 (32%), Gaps = 35/193 (18%) Query: 91 STSLSIEEERFLDAAEYGNIPVVRKMLEECHSLNVNCVDYMGQ--NALQLAVANEHLEIT 148 + L + LDAA+ G + V+K+ N+NC D G+ L LA +LE+ Sbjct: 3 GSDLLRGDAALLDAAKKGCLARVQKLCTPE---NINCRDTQGRNSTPLHLAAGYNNLEVA 59 Query: 149 ELLLKKENLSRVGD-----ALLLAISKGYVRIVEAILNHPAFAEGKRLATSPSQSELQQD 203 E LL+ D L A S G+V I ++ + Sbjct: 60 EYLLEHGADVNAQDKGGLIPLHNAASYGHVDIAALLIKYNTC------------------ 101 Query: 204 DFYAYDEDGTRFSHDVTPIILAAHCQEYEIVHTLLRKGARIERPHDYFCKCTECSQKQKH 263 A D+ TP+ AA ++ LL GA + + + Sbjct: 102 -VNATDKWA------FTPLHEAAQKGRTQLCALLLAHGADPTMKNQEGQTPLDLATADDI 154 Query: 264 DSFSHSRSRINAY 276 + N Y Sbjct: 155 RALLIDAMPENLY 167 >5HKP-A nrPDB Length = 351 Score = 86.0 bits (211), Expect = 6e-17, Method: Composition-based stats. Identities = 39/154 (25%), Positives = 54/154 (35%), Gaps = 35/154 (22%) Query: 97 EEERFLDAAEYGNIPVVRKMLEECHSLNVNCVDYMGQ--NALQLAVANEHLEITELLLKK 154 +++ L+AA GN K++ LNVNC G+ L LA + I +LLL+ Sbjct: 24 KKDELLEAARSGNE---EKLMALLTPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQH 80 Query: 155 ENLSRVGD-----ALLLAISKGYVRIVEAILNHPAFAEGKRLATSPSQSELQQDDFYAYD 209 D L A S G+ + E +L H A A D Sbjct: 81 GADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGAC-------------------VNAMD 121 Query: 210 EDGTRFSHDVTPIILAAHCQEYEIVHTLLRKGAR 243 TP+ AA E+ LL GA Sbjct: 122 LW------QFTPLHEAASKNRVEVCSLLLSHGAD 149 Score = 67.1 bits (162), Expect = 3e-11, Method: Composition-based stats. Identities = 42/258 (16%), Positives = 82/258 (31%), Gaps = 52/258 (20%) Query: 86 MFNDHSTSLSIEEERFL----DAAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLAVA 141 + H + +++ L +A YG+ V +L+ H VN +D L A + Sbjct: 76 LLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLK--HGACVNAMDLWQFTPLHEAAS 133 Query: 142 NEHLEITELLLKKENL---SRV-----------------------GDALLLAISKGYVRI 175 +E+ LLL G +LL A + + Sbjct: 134 KNRVEVCSLLLSHGADPTLVNCHGKSAVDMAPTPELRERLTYEFKGHSLLQAAREADLAK 193 Query: 176 VEAIL-----------NHPAFAEGKRLATSPSQSELQQDDFYAYDEDGTRFSHDVTPIIL 224 V+ L +H + P + ++ + + +TP+ + Sbjct: 194 VKKTLALEIINFKQPQSHETALHCAVASLHPKRKQVAELLLRKGANVNEKNKDFMTPLHV 253 Query: 225 AAHCQEYEIVHTLLRKGARIERPHDYFCKCTECSQKQKHDSFSHSRSRINAYKGLASPAY 284 AA +++ L + GA++ + H R+ G + P+ Sbjct: 254 AAERAHNDVMEVLHKHGAKMNALDSLGQTALHRAALAGH----LQTCRLLLSYG-SDPSI 308 Query: 285 LSLSSEDPVMTALELSNE 302 +SL TA ++ NE Sbjct: 309 ISLQG----FTAAQMGNE 322 Score = 55.2 bits (131), Expect = 1e-07, Method: Composition-based stats. Identities = 23/124 (18%), Positives = 46/124 (37%), Gaps = 6/124 (4%) Query: 84 AYMFNDHSTSLSIEEERFLD----AAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLA 139 A + +++ + + F+ AAE + V+ + H +N +D +GQ AL A Sbjct: 230 AELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVL--HKHGAKMNALDSLGQTALHRA 287 Query: 140 VANEHLEITELLLKKENLSRVGDALLLAISKGYVRIVEAILNHPAFAEGKRLATSPSQSE 199 HL+ LLL + + ++ V+ IL+ + ++ Sbjct: 288 ALAGHLQTCRLLLSYGSDPSIISLQGFTAAQMGNEAVQQILSESTPMRTSDVDYRLLEAS 347 Query: 200 LQQD 203 D Sbjct: 348 KAGD 351 Score = 42.1 bits (97), Expect = 0.001, Method: Composition-based stats. Identities = 22/109 (20%), Positives = 36/109 (33%), Gaps = 10/109 (9%) Query: 159 RVGDALLLAISKGYVRIVEAILNHPAFAEGKRLATSPSQSELQQDDFYAYDEDGTRFSHD 218 + D A+ G + E + + E K +A L + + DG + Sbjct: 9 DLADPSAKAVLTGEYKKDELLEAARSGNEEKLMAL------LTPLNVNCHASDGRKS--- 59 Query: 219 VTPIILAAHCQEYEIVHTLLRKGARIERPHDYFCKCTECSQKQKHDSFS 267 TP+ LAA IV LL+ GA + + H + Sbjct: 60 -TPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVT 107 >6BY9-A nrPDB Length = 328 Score = 82.1 bits (201), Expect = 9e-16, Method: Composition-based stats. Identities = 38/169 (22%), Positives = 64/169 (37%), Gaps = 31/169 (18%) Query: 104 AAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLAVANEHLEITELLLKKENLSRVGDA 163 AAE G++ + +++ N++ + L A N HLE + L+K L DA Sbjct: 109 AAEAGHVDICHMLVQA--GANIDTCSEDQRTPLMEAAENNHLEAVKYLIKAGALVDPKDA 166 Query: 164 -----LLLAISKGYVRIVEAILNHPAFAEGKRLATSPSQSELQQDDFYAYDEDGTRFSHD 218 L LA KG+ +V+ +L++ Q D D+ G Sbjct: 167 EGSTCLHLAAKKGHYEVVQYLLSNG------------------QMDVNCQDDGG------ 202 Query: 219 VTPIILAAHCQEYEIVHTLLRKGARIERPHDYFCKCTECSQKQKHDSFS 267 TP+I A + ++V LL KG+ I + C + + Sbjct: 203 WTPMIWATEYKHVDLVKLLLSKGSDINIRDNEENICLHWAAFSGCVDIA 251 Score = 75.6 bits (184), Expect = 9e-14, Method: Composition-based stats. Identities = 35/161 (21%), Positives = 63/161 (39%), Gaps = 31/161 (19%) Query: 104 AAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLAVANEHLEITELLLKKENLSRVGD- 162 AA+ G+ VV+ +L ++VNC D G + A +H+++ +LLL K + + D Sbjct: 175 AAKKGHYEVVQYLLSNGQ-MDVNCQDDGGWTPMIWATEYKHVDLVKLLLSKGSDINIRDN 233 Query: 163 ----ALLLAISKGYVRIVEAILNHPAFAEGKRLATSPSQSELQQDDFYAYDEDGTRFSHD 218 L A G V I E +L + D +A + G Sbjct: 234 EENICLHWAAFSGCVDIAEILL-------------------AAKCDLHAVNIHGD----- 269 Query: 219 VTPIILAAHCQEYEIVHTLLRKGARIERPHDYFCKCTECSQ 259 +P+ +AA Y+ V L + + + + +C+ Sbjct: 270 -SPLHIAARENRYDCVVLFLSRDSDVTLKNKEGETPLQCAS 309 Score = 35.9 bits (81), Expect = 0.073, Method: Composition-based stats. Identities = 19/81 (23%), Positives = 31/81 (38%), Gaps = 4/81 (4%) Query: 189 KRLATSPSQSELQQDDFYAYDEDGTRFSHD----VTPIILAAHCQEYEIVHTLLRKGARI 244 K+L S Q ELQ+ D F + +P+ AA +I H L++ GA I Sbjct: 69 KQLYFSARQGELQKVLLMLVDGIDPNFKMEHQNKRSPLHAAAEAGHVDICHMLVQAGANI 128 Query: 245 ERPHDYFCKCTECSQKQKHDS 265 + + + + H Sbjct: 129 DTCSEDQRTPLMEAAENNHLE 149 >3B7B-A nrPDB Length = 237 Score = 82.1 bits (201), Expect = 9e-16, Method: Composition-based stats. Identities = 38/169 (22%), Positives = 64/169 (37%), Gaps = 31/169 (18%) Query: 104 AAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLAVANEHLEITELLLKKENLSRVGDA 163 AAE G++ + +++ N++ + L A N HLE + L+K L DA Sbjct: 18 AAEAGHVDICHMLVQA--GANIDTCSEDQRTPLMEAAENNHLEAVKYLIKAGALVDPKDA 75 Query: 164 -----LLLAISKGYVRIVEAILNHPAFAEGKRLATSPSQSELQQDDFYAYDEDGTRFSHD 218 L LA KG+ +V+ +L++ Q D D+ G Sbjct: 76 EGSTCLHLAAKKGHYEVVQYLLSNG------------------QMDVNCQDDGG------ 111 Query: 219 VTPIILAAHCQEYEIVHTLLRKGARIERPHDYFCKCTECSQKQKHDSFS 267 TP+I A + ++V LL KG+ I + C + + Sbjct: 112 WTPMIWATEYKHVDLVKLLLSKGSDINIRDNEENICLHWAAFSGCVDIA 160 Score = 75.6 bits (184), Expect = 9e-14, Method: Composition-based stats. Identities = 35/161 (21%), Positives = 63/161 (39%), Gaps = 31/161 (19%) Query: 104 AAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLAVANEHLEITELLLKKENLSRVGD- 162 AA+ G+ VV+ +L ++VNC D G + A +H+++ +LLL K + + D Sbjct: 84 AAKKGHYEVVQYLLSNGQ-MDVNCQDDGGWTPMIWATEYKHVDLVKLLLSKGSDINIRDN 142 Query: 163 ----ALLLAISKGYVRIVEAILNHPAFAEGKRLATSPSQSELQQDDFYAYDEDGTRFSHD 218 L A G V I E +L + D +A + G Sbjct: 143 EENICLHWAAFSGCVDIAEILL-------------------AAKCDLHAVNIHGD----- 178 Query: 219 VTPIILAAHCQEYEIVHTLLRKGARIERPHDYFCKCTECSQ 259 +P+ +AA Y+ V L + + + + +C+ Sbjct: 179 -SPLHIAARENRYDCVVLFLSRDSDVTLKNKEGETPLQCAS 218 Score = 34.8 bits (78), Expect = 0.19, Method: Composition-based stats. Identities = 10/46 (21%), Positives = 19/46 (41%) Query: 220 TPIILAAHCQEYEIVHTLLRKGARIERPHDYFCKCTECSQKQKHDS 265 +P+ AA +I H L++ GA I+ + + + H Sbjct: 13 SPLHAAAEAGHVDICHMLVQAGANIDTCSEDQRTPLMEAAENNHLE 58 >6DMR-A nrPDB Length = 730 Score = 81.0 bits (198), Expect = 2e-15, Method: Composition-based stats. Identities = 23/146 (15%), Positives = 57/146 (39%), Gaps = 8/146 (5%) Query: 601 AVVLSFSRIAYILPANESFGPLQISLGRTV-KDIFKFMVIFIMVFVAFMIGMFNLYSYYI 659 A+VL + + Y + GP I + + + D+ +F + +V + F F++ Sbjct: 457 ALVLGWCSVMYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMAVVILGFASA-FHITFQTE 515 Query: 660 GAKQNEAFTTVEESFKTLFWAIFGLSEVKSVVINYNHKF-IENIGYVLYGVYNVTMVIVL 718 F+ + + F + + N+ + + + Y + + +++ Sbjct: 516 DPNNLGEFSDYPTALFSTF-----ELFLTIIDGPANYSVDLPFMYCITYAAFAIIATLLM 570 Query: 719 LNMLIAMINSSFQEIEDDADVEWKFA 744 LN+ IAM+ + + + D W+ Sbjct: 571 LNLFIAMMGDTHWRVAQERDELWRAQ 596 Score = 53.6 bits (127), Expect = 3e-07, Method: Composition-based stats. Identities = 35/170 (20%), Positives = 59/170 (34%), Gaps = 24/170 (14%) Query: 96 IEEERFLDAAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLAVANEHLEITELLLKKE 155 I + L AA N + K+L S + +G+ AL +A ++LE LL++ Sbjct: 44 IRDSPLLQAA-KENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLMEAA 102 Query: 156 NLSR----------VGDALLLAISKGYVRIVEAILNHPAFAEGKRLATSPSQSELQQDDF 205 AL +A+ + +V A+L A + + + ++ Sbjct: 103 PELAKEPALCEPFVGQTALHIAVMNQNLNLVRALLARGASVSAR-----ATGAAFRRSPH 157 Query: 206 YAYDEDGTRFSHDVTPIILAAHCQEYEIVHTLLRKGARIERPHDYFCKCT 255 + P+ AA EIV L+ GA I R D Sbjct: 158 NLI-------YYGEHPLSFAACVGSEEIVRLLIEHGADI-RAQDSLGNTV 199 Score = 44.4 bits (103), Expect = 2e-04, Method: Composition-based stats. Identities = 36/194 (18%), Positives = 59/194 (30%), Gaps = 43/194 (22%) Query: 87 FNDHSTSLSIEEERFLDAAEYGNIPVVRKMLEECHSLNVN---CVDYMGQNALQLAVANE 143 F + E AA Y N+ ++E L C ++GQ AL +AV N+ Sbjct: 72 FQQRGA---VGETALHVAALYDNLEAATLLMEAAPELAKEPALCEPFVGQTALHIAVMNQ 128 Query: 144 HLEITELLLKKENLS------------------RVGDALLLAISKGYVRIVEAILNHPAF 185 +L + LL + L A G IV ++ H A Sbjct: 129 NLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHPLSFAACVGSEEIVRLLIEHGAD 188 Query: 186 AEGKR-----------LATSPSQSELQQDDFYAYDEDGTRFS--------HDVTPIILAA 226 + L + + + + +YDE +TP LA Sbjct: 189 IRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDEHSDHLQSLELVPNHQGLTPFKLAG 248 Query: 227 HCQEYEIVHTLLRK 240 + L++K Sbjct: 249 VEGNTVMFQHLMQK 262 >6BOA-A nrPDB Length = 742 Score = 79.4 bits (194), Expect = 6e-15, Method: Composition-based stats. Identities = 24/146 (16%), Positives = 58/146 (39%), Gaps = 8/146 (5%) Query: 601 AVVLSFSRIAYILPANESFGPLQISLGRTV-KDIFKFMVIFIMVFVAFMIGMFNLYSYYI 659 A+VL + + Y + GP I + + + D+ +F + +V + F F + Sbjct: 457 ALVLGWCNVMYFAEGFQMLGPFTIMIQKMIFGDLMRFCWLMAVVILGFASA-FYIIFQTE 515 Query: 660 GAKQNEAFTTVEESFKTLFWAIFGLSEVKSVVINYNHKF-IENIGYVLYGVYNVTMVIVL 718 ++ F + + F + + N+ + + + Y + + +++ Sbjct: 516 DPEELGHFYDYPMALFSTF-----ELFLTIIDGPANYNVDLPFMYSITYAAFAIIATLLM 570 Query: 719 LNMLIAMINSSFQEIEDDADVEWKFA 744 LN+LIAM+ + + + D W+ Sbjct: 571 LNLLIAMMGDTHWRVAHERDELWRAQ 596 Score = 56.0 bits (133), Expect = 8e-08, Method: Composition-based stats. Identities = 38/168 (22%), Positives = 63/168 (37%), Gaps = 24/168 (14%) Query: 98 EERFLDAAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLAVANEHLEITELLLKKE-- 155 E L AA+ ++ + K+L+ V+ MG+ AL +A ++LE +L++ Sbjct: 46 ESPLLLAAKDNDVQALNKLLKYED-CKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPE 104 Query: 156 --------NLSRVGDALLLAISKGYVRIVEAILNHPAFAEGKRLATSPSQSELQQDDFYA 207 L AL +A+ + +V A+L A + T+ +S F Sbjct: 105 LVFEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGE 164 Query: 208 YDEDGTRFSHDVTPIILAAHCQEYEIVHTLLRKGARIERPHDYFCKCT 255 + P+ AA EIV L+ GA I R D Sbjct: 165 H------------PLSFAACVNSEEIVRLLIEHGADI-RAQDSLGNTV 199 >6E2G-A nrPDB Length = 727 Score = 79.4 bits (194), Expect = 6e-15, Method: Composition-based stats. Identities = 24/146 (16%), Positives = 57/146 (39%), Gaps = 8/146 (5%) Query: 601 AVVLSFSRIAYILPANESFGPLQISLGRTV-KDIFKFMVIFIMVFVAFMIGMFNLYSYYI 659 A+VL + + Y + GP I + + + D+ +F + +V + F F + Sbjct: 456 ALVLGWCNVMYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMAVVILGFASA-FYIIFQTE 514 Query: 660 GAKQNEAFTTVEESFKTLFWAIFGLSEVKSVVINYNHKF-IENIGYVLYGVYNVTMVIVL 718 + F + + F + + N+ + + + Y + + +++ Sbjct: 515 DPDELGHFYDYPMALFSTF-----ELFLTIIDGPANYDVDLPFMYSITYAAFAIIATLLM 569 Query: 719 LNMLIAMINSSFQEIEDDADVEWKFA 744 LN+LIAM+ + + + D W+ Sbjct: 570 LNLLIAMMGDTHWRVAHERDELWRAQ 595 Score = 60.2 bits (144), Expect = 4e-09, Method: Composition-based stats. Identities = 40/168 (23%), Positives = 63/168 (37%), Gaps = 24/168 (14%) Query: 98 EERFLDAAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLAVANEHLEITELLLKKE-- 155 E L AA+ N+ + K+L+ V+ MG+ AL +A ++LE +L++ Sbjct: 46 ESPLLLAAKENNVQALIKLLKF-EGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAAPE 104 Query: 156 --------NLSRVGDALLLAISKGYVRIVEAILNHPAFAEGKRLATSPSQSELQQDDFYA 207 L AL +A+ V +V A+L A + + S + + Sbjct: 105 LVFEPMTSELYEGQTALHIAVINQNVNLVRALLARGASVSARA---TGSVFHYRPHNLIY 161 Query: 208 YDEDGTRFSHDVTPIILAAHCQEYEIVHTLLRKGARIERPHDYFCKCT 255 Y E P+ AA EIV L+ GA I R D Sbjct: 162 YGEH---------PLSFAACVGSEEIVRLLIEHGADI-RAQDSLGNTV 199 Score = 42.1 bits (97), Expect = 0.001, Method: Composition-based stats. Identities = 35/182 (19%), Positives = 56/182 (30%), Gaps = 39/182 (21%) Query: 98 EERFLDAAEYGNIPVVRKMLEECHSL---NVNCVDYMGQNALQLAVANEHLEITELLLKK 154 E AA Y N+ ++E L + Y GQ AL +AV N+++ + LL + Sbjct: 80 ETALHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTALHIAVINQNVNLVRALLAR 139 Query: 155 ENLS------------------RVGDALLLAISKGYVRIVEAILNHPAFAEGKR------ 190 L A G IV ++ H A + Sbjct: 140 GASVSARATGSVFHYRPHNLIYYGEHPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTV 199 Query: 191 ---LATSPSQSELQQDDFYAYDEDGTRF---------SHDVTPIILAAHCQEYEIVHTLL 238 L P+++ Q DG + +TP LA + L+ Sbjct: 200 LHILILQPNKTFACQMYNLLLSYDGGDHLKSLELVPNNQGLTPFKLAGVEGNIVMFQHLM 259 Query: 239 RK 240 +K Sbjct: 260 QK 261 >5JHQ-A nrPDB Length = 482 Score = 77.9 bits (190), Expect = 2e-14, Method: Composition-based stats. Identities = 37/214 (17%), Positives = 73/214 (34%), Gaps = 38/214 (17%) Query: 84 AYMFNDHSTSLSIEEERFLDAAEYGNIPVVRKMLEECHSLNVNCVDYMGQ--NALQLAVA 141 ++M + ++S L+A G++ V+++++ NVN D G+ + L A Sbjct: 2 SHMASTGVPAVSGALRELLEACRNGDVSRVKRLVDAA---NVNAKDMAGRKSSPLHFAAG 58 Query: 142 NEHLEITELLLKKENLSRVGD-----ALLLAISKGYVRIVEAILNHPAFAEGKRLATSPS 196 ++ E LL+ D L A S G+ +V +L A Sbjct: 59 FGRKDVVEHLLQMGANVHARDDGGLIPLHNACSFGHAEVVSLLLCQGA------------ 106 Query: 197 QSELQQDDFYAYDEDGTRFSHDVTPIILAAHCQEYEIVHTLLRKGARIERPHDYFCKCTE 256 D A D + TP+ AA + ++ LL+ GA + + Sbjct: 107 -------DPNARDNW------NYTPLHEAAIKGKIDVCIVLLQHGADPNIRNTDGKSALD 153 Query: 257 CSQKQKHDSFSHSRSR---INAYKGLASPAYLSL 287 + + + + A + ++L Sbjct: 154 LADPSAKAVLTGEYKKDELLEAARSGNEEKLMAL 187 Score = 76.0 bits (185), Expect = 8e-14, Method: Composition-based stats. Identities = 48/222 (21%), Positives = 79/222 (35%), Gaps = 43/222 (19%) Query: 104 AAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLAVANEHLEITELLLKKENLSRVGD- 162 AA Y + +V+ +L+ H +V+ D G L A + H E+TELLLK D Sbjct: 209 AAGYNRVRIVQLLLQ--HGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGACVNAMDL 266 Query: 163 ----ALLLAISKGYVRIVEAILNHPA--------FAEGKRLATSPSQSELQQDDFYAYDE 210 L A SK V + +L+H A +A +P E +F + Sbjct: 267 WQFTPLHEAASKNRVEVCSLLLSHGADPTLVNCHGKSAVDMAPTPELRERLTYEFKGHSL 326 Query: 211 ---------------------DGTRFSHDVTPIILAA---HCQEYEIVHTLLRKGARIER 246 + + T + A H + ++ LLRKGA + Sbjct: 327 LQAAREADLAKVKKTLALEIINFKQPQSHETALHCAVASLHPKRKQVTELLLRKGANVNE 386 Query: 247 PHDYFCKCTECSQKQKHD---SFSHSR-SRINAYKGLASPAY 284 + F + ++ H+ H +++NA L A Sbjct: 387 KNKDFMTPLHVAAERAHNDVMEVLHKHGAKMNALDTLGQTAL 428 Score = 73.7 bits (179), Expect = 3e-13, Method: Composition-based stats. Identities = 41/198 (20%), Positives = 61/198 (30%), Gaps = 36/198 (18%) Query: 104 AAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLAVANEHLEITELLLKKENLSRVGD- 162 AA +G VV +L+ NV+ D G L A + H E+ LLL + D Sbjct: 56 AAGFGRKDVVEHLLQM--GANVHARDDGGLIPLHNACSFGHAEVVSLLLCQGADPNARDN 113 Query: 163 ----ALLLAISKGYVRIVEAILNHPAFAEGKRL------------ATSPSQSELQQDDFY 206 L A KG + + +L H A + A + E ++D+ Sbjct: 114 WNYTPLHEAAIKGKIDVCIVLLQHGADPNIRNTDGKSALDLADPSAKAVLTGEYKKDELL 173 Query: 207 AYDEDGTRFS-----------------HDVTPIILAAHCQEYEIVHTLLRKGARIERPHD 249 G TP+ LAA IV LL+ GA + Sbjct: 174 EAARSGNEEKLMALLTPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQHGADVHAKDK 233 Query: 250 YFCKCTECSQKQKHDSFS 267 + H + Sbjct: 234 GGLVPLHNACSYGHYEVT 251 Score = 67.1 bits (162), Expect = 4e-11, Method: Composition-based stats. Identities = 42/258 (16%), Positives = 82/258 (31%), Gaps = 52/258 (20%) Query: 86 MFNDHSTSLSIEEERFL----DAAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLAVA 141 + H + +++ L +A YG+ V +L+ H VN +D L A + Sbjct: 220 LLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLK--HGACVNAMDLWQFTPLHEAAS 277 Query: 142 NEHLEITELLLKKENL---SRV-----------------------GDALLLAISKGYVRI 175 +E+ LLL G +LL A + + Sbjct: 278 KNRVEVCSLLLSHGADPTLVNCHGKSAVDMAPTPELRERLTYEFKGHSLLQAAREADLAK 337 Query: 176 VEAIL-----------NHPAFAEGKRLATSPSQSELQQDDFYAYDEDGTRFSHDVTPIIL 224 V+ L +H + P + ++ + + +TP+ + Sbjct: 338 VKKTLALEIINFKQPQSHETALHCAVASLHPKRKQVTELLLRKGANVNEKNKDFMTPLHV 397 Query: 225 AAHCQEYEIVHTLLRKGARIERPHDYFCKCTECSQKQKHDSFSHSRSRINAYKGLASPAY 284 AA +++ L + GA++ + H R+ G + P+ Sbjct: 398 AAERAHNDVMEVLHKHGAKMNALDTLGQTALHRAALAGH----LQTCRLLLSYG-SDPSI 452 Query: 285 LSLSSEDPVMTALELSNE 302 +SL TA ++ NE Sbjct: 453 ISLQG----FTAAQMGNE 466 Score = 54.4 bits (129), Expect = 2e-07, Method: Composition-based stats. Identities = 21/106 (19%), Positives = 41/106 (38%), Gaps = 6/106 (5%) Query: 84 AYMFNDHSTSLSIEEERFLD----AAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLA 139 + +++ + + F+ AAE + V+ + H +N +D +GQ AL A Sbjct: 374 TELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVL--HKHGAKMNALDTLGQTALHRA 431 Query: 140 VANEHLEITELLLKKENLSRVGDALLLAISKGYVRIVEAILNHPAF 185 HL+ LLL + + ++ V+ IL+ Sbjct: 432 ALAGHLQTCRLLLSYGSDPSIISLQGFTAAQMGNEAVQQILSESTP 477 >5AN8-A nrPDB Length = 613 Score = 76.8 bits (187), Expect = 4e-14, Method: Composition-based stats. Identities = 24/143 (16%), Positives = 63/143 (44%), Gaps = 6/143 (4%) Query: 605 SFSRIAYILPANESFGPLQISLGRTV-KDIFKFMVIFIMVFVAFMIGMFNLYSYYIGAKQ 663 + + Y + G + + + + +D+ +F++++++ F + + +L S + Sbjct: 431 GWLNLLYYTRGFQHTGIYSVMIQKVILRDLLRFLLVYLVFLFGFAVALVSL-SREAQEDE 489 Query: 664 NEAFTTVEESFKTLFWAIFGLSEVKSVVINYNHKFIENIGYVLYGVYNVTMVIVLLNMLI 723 + ++ ++ LF G+ E+ + +L Y + ++LLNMLI Sbjct: 490 APPYRSILDASLELFKFTIGMGELAF----QEQLRFRGVVLLLLLAYVLLTYVLLLNMLI 545 Query: 724 AMINSSFQEIEDDADVEWKFARA 746 A+++ + + D+ WK +A Sbjct: 546 ALMSETVNSVATDSWSIWKLQKA 568 Score = 44.0 bits (102), Expect = 3e-04, Method: Composition-based stats. Identities = 33/182 (18%), Positives = 54/182 (29%), Gaps = 47/182 (25%) Query: 123 LNVNCVD--YMGQNALQLAVANEHLEITELLLKKENLSRVGD------------------ 162 +N C D Y G +AL +A+ L+ +LL++ Sbjct: 76 VNAQCTDEYYRGHSALHIAIEKRSLQCVKLLVENGANVHAKACGHFFQKNQDTCFYFGEL 135 Query: 163 ALLLAISKGYVRIVEAILNHPAFAEGKRLATSPSQSELQQDDFYAYD------------- 209 L LA +V +L +P A + S + L A + Sbjct: 136 PLSLAACTKQWDVVNYLLENPHPAASLQAQDSLGNTVLHALVMIADNSPENSALVVRMYD 195 Query: 210 ---EDGTRFSHDV-----------TPIILAAHCQEYEIVHTLLRKGARIERPHDYFCKCT 255 + G R +V TP+ LAA + EI +L++ Sbjct: 196 GLLQAGARLCPNVQLEGIPNLEGLTPLKLAAKEGKIEIFKHILQREFSAPCQSLSRKFTE 255 Query: 256 EC 257 C Sbjct: 256 WC 257 >6BWI-A nrPDB Length = 977 Score = 74.8 bits (182), Expect = 2e-13, Method: Composition-based stats. Identities = 35/196 (17%), Positives = 76/196 (38%), Gaps = 29/196 (14%) Query: 597 LYAIAVVLSFSRIAYILPANESFGPLQISLGRTVKDIFKFMVIFIMVFVAFMIGMFNLYS 656 + I ++ R+ +I N+ GP + + + +KD+F F+ + VA+ + L Sbjct: 695 VLCIDFMVFTVRLLHIFTVNKQLGPKIVIVSKMMKDVFFFLFFLGVWLVAYGVATEGLLR 754 Query: 657 YYIGAKQNEAFTTVEESFKTLFWAIFGLSEVKSVVI----NYNHKFIENI---GYVLYGV 709 + ++ + + F + IFG + + + + N Sbjct: 755 ----PRDSDFPSILRRVFYRPYLQIFGQIPQEDMDVALMEHSNCSSEPGFWAHPPGAQAG 810 Query: 710 YNVTMV-----------------IVLLNMLIAMINSSFQEIEDDADVEWKFARAKLWFSY 752 V+ I+L+N+LIAM + +F +++ ++D+ WK R +L + Sbjct: 811 TCVSQYANWLVVLLLVIFLLVANILLVNLLIAMFSYTFGKVQGNSDLYWKAQRYRLIREF 870 Query: 753 FEEGRTLPVPFNLVPS 768 L PF ++ Sbjct: 871 HSRP-ALAPPFIVISH 885 >6OO7-A nrPDB Length = 786 Score = 71.4 bits (173), Expect = 2e-12, Method: Composition-based stats. Identities = 21/171 (12%), Positives = 68/171 (39%), Gaps = 26/171 (15%) Query: 597 LYAIAVVLSFSRIAYILPANESFGPLQISLGRTV-KDIFKFMVIFIMVFVAFMIGMFNLY 655 L ++ + ++ + Y + G + + + + +D+ +F++++++ F + + +L Sbjct: 498 LLVSSLAMGWTNLLYYTRGFQHTGIYSVMIEKVILRDLLRFLLVYLVFLFGFAVALVSLS 557 Query: 656 SYYIGAK-------------------QNEAFTTVEESFKTLFWAIFGLSEV-KSVVINYN 695 ++ + + ++ ++ LF G+ E+ + + Sbjct: 558 REAQNSRTPAGPNATEVGQPGAGQEDEAPPYRSILDASLELFKFTIGMGELAFQEQLRFR 617 Query: 696 HKFIENIGYVLYGVYNVTMVIVLLNMLIAMINSSFQEIEDDADVEWKFARA 746 + + + Y + + NMLIA+++ + + D+ WK +A Sbjct: 618 GVVLLLLLAYVLLTYVLLL-----NMLIALMSETVNSVATDSWSIWKLQKA 663 Score = 44.4 bits (103), Expect = 2e-04, Method: Composition-based stats. Identities = 33/182 (18%), Positives = 53/182 (29%), Gaps = 47/182 (25%) Query: 123 LNVNCVD--YMGQNALQLAVANEHLEITELLLKKENLSRVGD------------------ 162 +N C D Y G +AL +A+ L+ +LL++ Sbjct: 151 VNAQCTDEYYRGHSALHIAIEKRSLQCVKLLVENGANVHAKACGHFFQKNQDTCFYFGEL 210 Query: 163 ALLLAISKGYVRIVEAILNHPAFAEGKRLATSPSQSELQQDDFYAYD------------- 209 L LA +V +L +P + S + L A D Sbjct: 211 PLSLAACTKQWDVVNYLLENPHQPASLQAQDSLGNTVLHALVMIADDSAENSALVVRMYD 270 Query: 210 ---EDGTRFSHDV-----------TPIILAAHCQEYEIVHTLLRKGARIERPHDYFCKCT 255 + G R +V TP+ LAA + EI +L++ Sbjct: 271 GLLQAGARLCPNVQLEGIPNLEGLTPLKLAAKEGKIEIFKHILQREFSAPCQSLSRKFTE 330 Query: 256 EC 257 C Sbjct: 331 WC 332 >4NIK-A nrPDB Length = 230 Score = 67.9 bits (164), Expect = 2e-11, Method: Composition-based stats. Identities = 35/154 (22%), Positives = 57/154 (37%), Gaps = 15/154 (9%) Query: 104 AAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLAVANEHLEITELLLKKENLSRV--- 160 A G+ +V +L+ + VN D G + L +A + EI + LL K Sbjct: 51 ACSAGHTEIVEFLLQL--GVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQ 108 Query: 161 --GDALLLAISKGYVRIVEAILNHPAFAEGKR------LATSPSQSELQQDDFYAYDEDG 212 L A SK I +L A + K + + ++ L+ Y + Sbjct: 109 NGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKAS 168 Query: 213 TRF--SHDVTPIILAAHCQEYEIVHTLLRKGARI 244 T + TP+ LA + E L+ +GA I Sbjct: 169 TNIQDTEGNTPLHLACDEERVEEAKLLVSQGASI 202 Score = 63.7 bits (153), Expect = 4e-10, Method: Composition-based stats. Identities = 38/169 (22%), Positives = 58/169 (34%), Gaps = 31/169 (18%) Query: 105 AEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLAVANEHLEITELLLKKENLSRVGD-- 162 A G + +++ + SL D + AL A + H EI E LL+ D Sbjct: 18 AYSGKLEELKESILADKSLATR-TDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDA 76 Query: 163 ---ALLLAISKGYVRIVEAILNHPAFAEGKRLATSPSQSELQQDDFYAYDEDGTRFSHDV 219 L +A S G IV+A+L A A +++G Sbjct: 77 GWSPLHIAASAGRDEIVKALLGKGA-------------------QVNAVNQNG------C 111 Query: 220 TPIILAAHCQEYEIVHTLLRKGARIERPHDYFCKCTECSQKQKHDSFSH 268 TP+ AA +EI LL GA + Y + + + H Sbjct: 112 TPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIH 160 Score = 40.9 bits (94), Expect = 0.003, Method: Composition-based stats. Identities = 18/81 (22%), Positives = 31/81 (38%), Gaps = 6/81 (7%) Query: 84 AYMFNDHSTSLSI----EEERFLDAAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLA 139 A M + + E AA GN+ ++ +L + + N D G L LA Sbjct: 126 AVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLY--YKASTNIQDTEGNTPLHLA 183 Query: 140 VANEHLEITELLLKKENLSRV 160 E +E +LL+ + + Sbjct: 184 CDEERVEEAKLLVSQGASIYI 204 >3ZKJ-A nrPDB Length = 261 Score = 67.5 bits (163), Expect = 3e-11, Method: Composition-based stats. Identities = 34/156 (21%), Positives = 60/156 (38%), Gaps = 14/156 (8%) Query: 103 DAAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLAVANEHLEITELLLKKENLSRV-- 160 +AA +G+ +R ++ + ++N+ D++ + L A HL ++LLK Sbjct: 9 EAAIHGHQLSLRNLISQGWAVNIITADHV--SPLHEACLGGHLSCVKILLKHGAQVNGVT 66 Query: 161 ---GDALLLAISKGYVRIVEAILNHPAFAEGKRLATSPSQSELQQDDFYAYDE------- 210 L A G V +L H A + + SP ++ + Sbjct: 67 ADWHTPLFNACVSGSWDCVNLLLQHGASVQPESDLASPIHEAARRGHVECVNSLIAYGGN 126 Query: 211 DGTRFSHDVTPIILAAHCQEYEIVHTLLRKGARIER 246 + SH TP+ LA Q+ V LL GA + + Sbjct: 127 IDHKISHLGTPLYLACENQQRACVKKLLESGADVNQ 162 Score = 66.4 bits (160), Expect = 6e-11, Method: Composition-based stats. Identities = 28/169 (16%), Positives = 56/169 (33%), Gaps = 13/169 (7%) Query: 101 FLDAAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLAVANEHLEITELLLKKENLS-- 158 +A G++ V+ +L+ H VN V L A + + LLL+ Sbjct: 40 LHEACLGGHLSCVKILLK--HGAQVNGVTADWHTPLFNACVSGSWDCVNLLLQHGASVQP 97 Query: 159 --RVGDALLLAISKGYVRIVEAILNHPAFAEGK----RLATSPSQSELQQDDFYAYDEDG 212 + + A +G+V V +++ + + K + Q+ E G Sbjct: 98 ESDLASPIHEAARRGHVECVNSLIAYGGNIDHKISHLGTPLYLACENQQRACVKKLLESG 157 Query: 213 TRFSH---DVTPIILAAHCQEYEIVHTLLRKGARIERPHDYFCKCTECS 258 + +P+ A E+ L+ GA + + + E Sbjct: 158 ADVNQGKGQDSPLHAVARTASEELACLLMDFGADTQAKNAEGKRPVELV 206 Score = 47.5 bits (111), Expect = 3e-05, Method: Composition-based stats. Identities = 29/172 (16%), Positives = 55/172 (31%), Gaps = 42/172 (24%) Query: 133 QNALQLAVANEHLEITELLLKKENLSRVGD-----ALLLAISKGYVRIVEAILNHPAFAE 187 + + A + H L+ + + L A G++ V+ +L H A Sbjct: 4 WSPMHEAAIHGHQLSLRNLISQGWAVNIITADHVSPLHEACLGGHLSCVKILLKHGAQVN 63 Query: 188 GKRLATSPSQSELQQDDFYAYDEDGTRFSHDVTPIILAAHCQEYEIVHTLLRKGARIERP 247 G TP+ A ++ V+ LL+ GA + +P Sbjct: 64 GVTADWH-------------------------TPLFNACVSGSWDCVNLLLQHGASV-QP 97 Query: 248 HDYFCKCTECSQKQKHDSFSHSRSRINAYKG--------LASPAYLSLSSED 291 + ++ H +S + AY G L +P YL+ ++ Sbjct: 98 ESDLASPIHEAARRGHVECVNS---LIAYGGNIDHKISHLGTPLYLACENQQ 146 >6BO5-A nrPDB Length = 695 Score = 66.4 bits (160), Expect = 6e-11, Method: Composition-based stats. Identities = 25/159 (15%), Positives = 64/159 (40%), Gaps = 24/159 (15%) Query: 608 RIAYILPANESFGPLQISLGRTV-KDIFKFMVIFIMVFVAFMIGMFNLYSYYIGAK---Q 663 + Y + G + + + + +D+ +F++++++ F + + +L K Sbjct: 471 NLLYYTRGFQHTGIYSVMIQKVILRDLLRFLLVYLVFLFGFAVALVSLSREARSPKAPED 530 Query: 664 NEA----------------FTTVEESFKTLFWAIFGLSEVKSVVINYNHKFIENIGYVLY 707 N + + ++ ++ LF G+ E+ + +L Sbjct: 531 NNSTVTEQPTVGQEEEPAPYRSILDASLELFKFTIGMGELAF----QEQLRFRGVVLLLL 586 Query: 708 GVYNVTMVIVLLNMLIAMINSSFQEIEDDADVEWKFARA 746 Y + ++LLNMLIA+++ + + D++ WK +A Sbjct: 587 LAYVLLTYVLLLNMLIALMSETVNHVADNSWSIWKLQKA 625 Score = 40.2 bits (92), Expect = 0.004, Method: Composition-based stats. Identities = 32/182 (17%), Positives = 51/182 (28%), Gaps = 47/182 (25%) Query: 123 LNVNCVDYM--GQNALQLAVANEHLEITELLLKKENLSR---VGD--------------- 162 +N C D G +AL +A+ L+ +LL++ G Sbjct: 113 VNAQCTDEFYQGHSALHIAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGEL 172 Query: 163 ALLLAISKGYVRIVEAILNHPAFAEGKRLATSPSQSELQQDDFYAYD------------- 209 L LA +V +L +P S + L A + Sbjct: 173 PLSLAACTKQWDVVTYLLENPHQPASLEATDSLGNTVLHALVMIADNSPENSALVIHMYD 232 Query: 210 ---EDGTRFSHDV-----------TPIILAAHCQEYEIVHTLLRKGARIERPHDYFCKCT 255 + G R V TP+ LAA + EI +L++ Sbjct: 233 GLLQMGARLCPTVQLEEISNHQGLTPLKLAAKEGKIEIFRHILQREFSGPYQPLSRKFTE 292 Query: 256 EC 257 C Sbjct: 293 WC 294 Score = 30.5 bits (67), Expect = 3.7, Method: Composition-based stats. Identities = 17/105 (16%), Positives = 35/105 (33%), Gaps = 2/105 (1%) Query: 140 VANEHLEITELLLKKENLSRVGDALLLAISKGYVRIVEAILNHPAFAEGKRLATSPSQSE 199 V E + E L + N + D+ S G +++A+LN + + Sbjct: 48 VPEELTGLLEYL--RWNSKYLTDSAYTEGSTGKTCLMKAVLNLQDGVNACIMPLLQIDKD 105 Query: 200 LQQDDFYAYDEDGTRFSHDVTPIILAAHCQEYEIVHTLLRKGARI 244 + F + + +A + + V L+ GA + Sbjct: 106 SGNPKPLVNAQCTDEFYQGHSALHIAIEKRSLQCVKLLVENGADV 150 >5HI9-A nrPDB Length = 770 Score = 66.0 bits (159), Expect = 8e-11, Method: Composition-based stats. Identities = 35/278 (12%), Positives = 90/278 (32%), Gaps = 49/278 (17%) Query: 608 RIAYILPANESFGPLQISLGRTV-KDIFKFMVIFIMVFVAFMIGMFNLYSYYIGAK---Q 663 + Y + G + + + + +D+ +F++++++ F + + +L K Sbjct: 511 NLLYYTRGFQHTGIYSVMIQKVILRDLLRFLLVYLVFLFGFAVALVSLSREARSPKAPED 570 Query: 664 NEA----------------FTTVEESFKTLFWAIFGLSEV-KSVVINYNHKFIENIGYVL 706 N + + ++ ++ LF G+ E+ + + + + + Sbjct: 571 NNSTVTEQPTVGQEEEPAPYRSILDASLELFKFTIGMGELAFQEQLRFRGVVLLLLLAYV 630 Query: 707 YGVYNVTMVIVLLNMLIAMINSSFQEIEDDADVEWKFARAKLWFSYFEEGRTLPVPFNLV 766 Y + + NMLIA+++ + + D++ WK +A +++ Sbjct: 631 LLTYVLLL-----NMLIALMSETVNHVADNSWSIWKLQKA----------------ISVL 669 Query: 767 PSPKSLLYLLLKFKKWMCELIQGQKQGFQEDAEMNKRNE-------EKKFGISGSHEDLS 819 + K + L G + D R E EK Sbjct: 670 EMENGYWWCRRKKHREGRLLKVGTRGDGTPDERWCFRVEEVNWAAWEKTLPTLSEDPSGP 729 Query: 820 KFSLDKNQLAHNKQSSTRSSEDYHLNSFSNPPRQYQKI 857 + +K ++ S ED+ P + ++ Sbjct: 730 GITGNKKNPTSKPGKNSASEEDHLPLQVLQSPTETSQV 767 Score = 40.2 bits (92), Expect = 0.004, Method: Composition-based stats. Identities = 32/182 (17%), Positives = 51/182 (28%), Gaps = 47/182 (25%) Query: 123 LNVNCVDYM--GQNALQLAVANEHLEITELLLKKENLSR---VGD--------------- 162 +N C D G +AL +A+ L+ +LL++ G Sbjct: 153 VNAQCTDEFYQGHSALHIAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGEL 212 Query: 163 ALLLAISKGYVRIVEAILNHPAFAEGKRLATSPSQSELQQDDFYAYD------------- 209 L LA +V +L +P S + L A + Sbjct: 213 PLSLAACTKQWDVVTYLLENPHQPASLEATDSLGNTVLHALVMIADNSPENSALVIHMYD 272 Query: 210 ---EDGTRFSHDV-----------TPIILAAHCQEYEIVHTLLRKGARIERPHDYFCKCT 255 + G R V TP+ LAA + EI +L++ Sbjct: 273 GLLQMGARLCPTVQLEEISNHQGLTPLKLAAKEGKIEIFRHILQREFSGPYQPLSRKFTE 332 Query: 256 EC 257 C Sbjct: 333 WC 334 Score = 30.5 bits (67), Expect = 3.7, Method: Composition-based stats. Identities = 17/105 (16%), Positives = 35/105 (33%), Gaps = 2/105 (1%) Query: 140 VANEHLEITELLLKKENLSRVGDALLLAISKGYVRIVEAILNHPAFAEGKRLATSPSQSE 199 V E + E L + N + D+ S G +++A+LN + + Sbjct: 88 VPEELTGLLEYL--RWNSKYLTDSAYTEGSTGKTCLMKAVLNLQDGVNACIMPLLQIDKD 145 Query: 200 LQQDDFYAYDEDGTRFSHDVTPIILAAHCQEYEIVHTLLRKGARI 244 + F + + +A + + V L+ GA + Sbjct: 146 SGNPKPLVNAQCTDEFYQGHSALHIAIEKRSLQCVKLLVENGADV 190 >2KXP-C nrPDB Length = 118 Score = 66.0 bits (159), Expect = 8e-11, Method: Composition-based stats. Identities = 27/116 (23%), Positives = 44/116 (37%), Gaps = 7/116 (6%) Query: 98 EERFLDAAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLAVANEHLEITELLLKKENL 157 ++ F+ A + G++ V+ + +VN G+ L A LEI E LL K Sbjct: 3 DKEFMWALKNGDLDEVKDYV--AKGEDVNRTLEGGRKPLHYAADCGQLEILEFLLLKGAD 60 Query: 158 SRVGD-----ALLLAISKGYVRIVEAILNHPAFAEGKRLATSPSQSELQQDDFYAY 208 D LL A+ +G+V V+ +L+ A K + A Sbjct: 61 INAPDKHHITPLLSAVYEGHVSCVKLLLSKGADKTVKGPDGLTALEATDNQAIKAL 116 Score = 42.1 bits (97), Expect = 0.001, Method: Composition-based stats. Identities = 15/45 (33%), Positives = 21/45 (46%) Query: 221 PIILAAHCQEYEIVHTLLRKGARIERPHDYFCKCTECSQKQKHDS 265 P+ AA C + EI+ LL KGA I P + + + H S Sbjct: 38 PLHYAADCGQLEILEFLLLKGADINAPDKHHITPLLSAVYEGHVS 82 >2DWZ-A nrPDB Length = 231 Score = 65.2 bits (157), Expect = 1e-10, Method: Composition-based stats. Identities = 34/154 (22%), Positives = 57/154 (37%), Gaps = 15/154 (9%) Query: 104 AAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLAVANEHLEITELLLKKENLSRV--- 160 A G+ +V +L+ + VN D G + L +A + EI + LL K Sbjct: 47 ACSAGHTEIVEFLLQL--GVPVNDKDDAGWSPLHIAASAGRDEIVKALLVKGAHVNAVNQ 104 Query: 161 --GDALLLAISKGYVRIVEAILNHPAFAEGKR------LATSPSQSELQQDDFYAYDEDG 212 L A SK I +L A + K + + ++ L+ + + Sbjct: 105 NGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYDATAMHRAAAKGNLKMVHILLFYKAS 164 Query: 213 TRF--SHDVTPIILAAHCQEYEIVHTLLRKGARI 244 T + TP+ LA + E L+ +GA I Sbjct: 165 TNIQDTEGNTPLHLACDEERVEEAKFLVTQGASI 198 Score = 63.3 bits (152), Expect = 5e-10, Method: Composition-based stats. Identities = 38/169 (22%), Positives = 58/169 (34%), Gaps = 31/169 (18%) Query: 105 AEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLAVANEHLEITELLLKKENLSRVGD-- 162 A G + +++ + SL D + AL A + H EI E LL+ D Sbjct: 14 AYSGKLDELKERILADKSLATR-TDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDA 72 Query: 163 ---ALLLAISKGYVRIVEAILNHPAFAEGKRLATSPSQSELQQDDFYAYDEDGTRFSHDV 219 L +A S G IV+A+L A A +++G Sbjct: 73 GWSPLHIAASAGRDEIVKALLVKGAH-------------------VNAVNQNG------C 107 Query: 220 TPIILAAHCQEYEIVHTLLRKGARIERPHDYFCKCTECSQKQKHDSFSH 268 TP+ AA +EI LL GA + Y + + + H Sbjct: 108 TPLHYAASKNRHEIAVMLLEGGANPDAKDHYDATAMHRAAAKGNLKMVH 156 Score = 39.4 bits (90), Expect = 0.008, Method: Composition-based stats. Identities = 17/81 (20%), Positives = 31/81 (38%), Gaps = 6/81 (7%) Query: 84 AYMFNDHSTSLSIEEE----RFLDAAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLA 139 A M + + ++ AA GN+ +V +L + + N D G L LA Sbjct: 122 AVMLLEGGANPDAKDHYDATAMHRAAAKGNLKMVHILLF--YKASTNIQDTEGNTPLHLA 179 Query: 140 VANEHLEITELLLKKENLSRV 160 E +E + L+ + + Sbjct: 180 CDEERVEEAKFLVTQGASIYI 200 >2RFA-A nrPDB Length = 232 Score = 61.7 bits (148), Expect = 2e-09, Method: Composition-based stats. Identities = 39/168 (23%), Positives = 63/168 (37%), Gaps = 24/168 (14%) Query: 98 EERFLDAAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLAVANEHLEITELLLKKE-- 155 E L AA+ ++ + K+L+ V+ MG+ AL +A ++LE +L++ Sbjct: 4 ESPLLLAAKENDVQALSKLLKF-EGCEVHQRGAMGETALHIAALYDNLEAAMVLMEAAPE 62 Query: 156 --------NLSRVGDALLLAISKGYVRIVEAILNHPAFAEGKRLATSPSQSELQQDDFYA 207 L AL +A+ V +V A+L A + + S + + Sbjct: 63 LVFEPMTSELYEGQTALHIAVINQNVNLVRALLARGASVSAR---ATGSVFHYRPHNLIY 119 Query: 208 YDEDGTRFSHDVTPIILAAHCQEYEIVHTLLRKGARIERPHDYFCKCT 255 Y E P+ AA EIV L+ GA I R D Sbjct: 120 YGEH---------PLSFAACVGSEEIVRLLIEHGADI-RAQDSLGNTV 157 Score = 42.9 bits (99), Expect = 7e-04, Method: Composition-based stats. Identities = 35/182 (19%), Positives = 56/182 (30%), Gaps = 39/182 (21%) Query: 98 EERFLDAAEYGNIPVVRKMLEECHSL---NVNCVDYMGQNALQLAVANEHLEITELLLKK 154 E AA Y N+ ++E L + Y GQ AL +AV N+++ + LL + Sbjct: 38 ETALHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTALHIAVINQNVNLVRALLAR 97 Query: 155 ENLS------------------RVGDALLLAISKGYVRIVEAILNHPAFAEGKR------ 190 L A G IV ++ H A + Sbjct: 98 GASVSARATGSVFHYRPHNLIYYGEHPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTV 157 Query: 191 ---LATSPSQSELQQDDFYAYDEDGTRF---------SHDVTPIILAAHCQEYEIVHTLL 238 L P+++ Q DG + +TP LA + L+ Sbjct: 158 LHILILQPNKTFACQMYNLLLSYDGGDHLKSLELVPNNQGLTPFKLAGVEGNIVMFQHLM 217 Query: 239 RK 240 +K Sbjct: 218 QK 219 >2V1Z-A nrPDB Length = 291 Score = 60.6 bits (145), Expect = 3e-09, Method: Composition-based stats. Identities = 19/92 (20%), Positives = 34/92 (36%), Gaps = 16/92 (17%) Query: 242 ARIERPHDYFCKCTECSQKQKHDSFSHSRSRIN-AYKGLASPAYL-SLSSED--PVMTAL 297 +++ D C+ SH R+ L S L S E+ P+M+ Sbjct: 5 VKVKDAEDQLCRT------------SHRPCRVGYIELDLNSGKILESFRPEERFPMMSTF 52 Query: 298 ELSNELAVLANIEKEFKNDYRKLSMQCKDFVV 329 ++ AVL+ I+ + R++ D V Sbjct: 53 KVLLCGAVLSRIDAGQEQLGRRIHYSQNDLVK 84 >3EU9-A nrPDB Length = 240 Score = 60.6 bits (145), Expect = 3e-09, Method: Composition-based stats. Identities = 31/170 (18%), Positives = 56/170 (32%), Gaps = 33/170 (19%) Query: 101 FLDAAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLAVANEHLEITELLLKKENLSR- 159 + A +YG R+++E +V D L A N +++ + + K + Sbjct: 13 IVKATQYGIYERCRELVEA--GYDVRQPDKENVTLLHWAAINNRIDLVKYYISKGAIVDQ 70 Query: 160 -VGD----ALLLAISKGYVRIVEAILNHPAFAEGKRLATSPSQSELQQDDFYAYDEDGTR 214 GD L A +G++ +V ++ + A D D +G Sbjct: 71 LGGDLNSTPLHWATRQGHLSMVVQLMKYGA-------------------DPSLIDGEGCS 111 Query: 215 FSHDVTPIILAAHCQEYEIVHTLLRKGARIERPHDYFCKCTECSQKQKHD 264 I LAA IV L+ KG ++ + + H Sbjct: 112 C------IHLAAQFGHTSIVAYLIAKGQDVDMMDQNGMTPLMWAAYRTHS 155 Score = 53.3 bits (126), Expect = 5e-07, Method: Composition-based stats. Identities = 25/165 (15%), Positives = 56/165 (33%), Gaps = 32/165 (19%) Query: 104 AAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLAVANEHLEITELLLKKENLSRVGD- 162 A G++ +V ++++ + + + +D G + + LA H I L+ K + D Sbjct: 83 ATRQGHLSMVVQLMK--YGADPSLIDGEGCSCIHLAAQFGHTSIVAYLIAKGQDVDMMDQ 140 Query: 163 ----ALLLAISKGY-VRIVEAILNHPAFAEGKRLATSPSQSELQQDDFYAYDEDGTRFSH 217 L+ A + + V +L D+ H Sbjct: 141 NGMTPLMWAAYRTHSVDPTRLLLTF-------------------NVSVNLGDK-----YH 176 Query: 218 DVTPIILAAHCQEYEIVHTLLRKGARIERPHDYFCKCTECSQKQK 262 T + A ++ LL GA ++ + + ++++K Sbjct: 177 KNTALHWAVLAGNTTVISLLLEAGANVDAQNIKGESALDLAKQRK 221 >1G3N-B nrPDB Length = 168 Score = 60.6 bits (145), Expect = 3e-09, Method: Composition-based stats. Identities = 32/122 (26%), Positives = 44/122 (36%), Gaps = 13/122 (10%) Query: 73 EKGRRLANRGPAYMFNDHSTSLSIEEERFLDAAEYGNIPVVRKMLEECHSLNVNCVDYMG 132 E RRL RG D + I DAA G + ++ +LE +VN D G Sbjct: 51 EIARRLLLRGANPDLKDRTGFAVIH-----DAARAGFLDTLQTLLEFQ--ADVNIEDNEG 103 Query: 133 QNALQLAVANEHLEITELLLKKENLSRVG------DALLLAISKGYVRIVEAILNHPAFA 186 L LA HL + E L+K + A LA G +V + + A Sbjct: 104 NLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQANGAGG 163 Query: 187 EG 188 Sbjct: 164 AT 165 Score = 56.3 bits (134), Expect = 7e-08, Method: Composition-based stats. Identities = 24/98 (24%), Positives = 41/98 (41%), Gaps = 7/98 (7%) Query: 98 EERFLDAAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLAVANEHLEITELLLKKENL 157 L + GN + R++L N + D G + A L+ + LL+ + Sbjct: 38 GRTALQVMKLGNPEIARRLLLR--GANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQAD 95 Query: 158 SRVGD-----ALLLAISKGYVRIVEAILNHPAFAEGKR 190 + D L LA +G++R+VE ++ H A G R Sbjct: 96 VNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHR 133 Score = 50.2 bits (118), Expect = 4e-06, Method: Composition-based stats. Identities = 28/153 (18%), Positives = 53/153 (34%), Gaps = 33/153 (21%) Query: 96 IEEERFLDAAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLAVANEHLEITELLLKKE 155 AA G++ + +L+ ++N + G+ ALQ+ + + EI LL + Sbjct: 4 PWGNELASAAARGDLEQLTSLLQNNVNVN--AQNGFGRTALQV-MKLGNPEIARRLLLRG 60 Query: 156 NLSRVGD-----ALLLAISKGYVRIVEAILNHPAFAEGKRLATSPSQSELQQDDFYAYDE 210 + D + A G++ ++ +L A D D Sbjct: 61 ANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQA-------------------DVNIEDN 101 Query: 211 DGTRFSHDVTPIILAAHCQEYEIVHTLLRKGAR 243 +G P+ LAA +V L++ A Sbjct: 102 EGNL------PLHLAAKEGHLRVVEFLVKHTAS 128 >4DXB-A nrPDB Length = 637 Score = 59.4 bits (142), Expect = 8e-09, Method: Composition-based stats. Identities = 16/65 (24%), Positives = 28/65 (43%), Gaps = 8/65 (12%) Query: 272 RINAYKG-----LASPAYL-SLSSED--PVMTALELSNELAVLANIEKEFKNDYRKLSMQ 323 ++ A G L S L S E+ P+M+ ++ AVL+ I+ + R++ Sbjct: 395 QLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRIDAGQEQLGRRIHYS 454 Query: 324 CKDFV 328 D V Sbjct: 455 QNDLV 459 >3GMW-A nrPDB Length = 261 Score = 59.0 bits (141), Expect = 9e-09, Method: Composition-based stats. Identities = 15/65 (23%), Positives = 28/65 (43%), Gaps = 8/65 (12%) Query: 272 RINAYKG-----LASPAYL-SLSSED--PVMTALELSNELAVLANIEKEFKNDYRKLSMQ 323 ++ A G L S L S E+ P+M+ ++ AVL+ ++ + R++ Sbjct: 12 QLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYS 71 Query: 324 CKDFV 328 D V Sbjct: 72 QNDLV 76 >3ZDJ-A nrPDB Length = 263 Score = 58.6 bits (140), Expect = 1e-08, Method: Composition-based stats. Identities = 18/78 (23%), Positives = 36/78 (46%), Gaps = 7/78 (8%) Query: 258 SQKQKHDSFSHSRSRINAYKG-----LASPAYLSLSSED--PVMTALELSNELAVLANIE 310 Q + S S+++ G LAS LS +++ P+M+ ++ AVLA ++ Sbjct: 1 MHPQTLEQIKESESQLSGRVGMVELDLASGRTLSYRADERFPMMSTFKVLLCGAVLARVD 60 Query: 311 KEFKNDYRKLSMQCKDFV 328 + R++ + +D V Sbjct: 61 AGLEQLDRRIHYRQQDLV 78 >1BLX-B nrPDB Length = 166 Score = 56.7 bits (135), Expect = 4e-08, Method: Composition-based stats. Identities = 31/174 (17%), Positives = 63/174 (36%), Gaps = 33/174 (18%) Query: 98 EERFLDAAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLAVANEHLEITELLLKKENL 157 +R AA G++ VR++L ++ + ++ G+ ALQ+ + + LLK+ Sbjct: 9 GDRLSGAAARGDVQEVRRLLHR-ELVHPDALNRFGKTALQVMMF-GSPAVALELLKQGAS 66 Query: 158 SRVGD-----ALLLAISKGYVRIVEAILNHPAFAEGKRLATSPSQSELQQDDFYAYDEDG 212 V D + A G++ ++ ++ H A D A D G Sbjct: 67 PNVQDASGTSPVHDAARTGFLDTLKVLVEHGA-------------------DVNALDSTG 107 Query: 213 TRFSHDVTPIILAAHCQEYEIVHTLLRKGARIERPHDYFCKCTECSQKQKHDSF 266 + PI LA +V L + + + E ++++ + Sbjct: 108 SL------PIHLAIREGHSSVVSFLAPE-SDLHHRDASGLTPLELARQRGAQNL 154 Score = 56.3 bits (134), Expect = 6e-08, Method: Composition-based stats. Identities = 24/148 (16%), Positives = 52/148 (35%), Gaps = 7/148 (4%) Query: 67 RQTILREKGRRLANRGPAYMFNDHSTSLSIEEERFLDAAEYGNIPVVRKMLEECHSLNVN 126 R + +G R + H +L+ + L +G+ V ++L++ + N Sbjct: 11 RLSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMMFGSPAVALELLKQ--GASPN 68 Query: 127 CVDYMGQNALQLAVANEHLEITELLLKKENLSRVGD-----ALLLAISKGYVRIVEAILN 181 D G + + A L+ ++L++ D + LAI +G+ +V + Sbjct: 69 VQDASGTSPVHDAARTGFLDTLKVLVEHGADVNALDSTGSLPIHLAIREGHSSVVSFLAP 128 Query: 182 HPAFAEGKRLATSPSQSELQQDDFYAYD 209 +P + Q+ D Sbjct: 129 ESDLHHRDASGLTPLELARQRGAQNLMD 156 Score = 54.8 bits (130), Expect = 2e-07, Method: Composition-based stats. Identities = 20/104 (19%), Positives = 40/104 (38%), Gaps = 10/104 (9%) Query: 87 FNDHSTSLSIEEER----FLDAAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLAVAN 142 S ++++ DAA G + ++ ++E H +VN +D G + LA+ Sbjct: 60 LLKQGASPNVQDASGTSPVHDAARTGFLDTLKVLVE--HGADVNALDSTGSLPIHLAIRE 117 Query: 143 EHLEITELLLK----KENLSRVGDALLLAISKGYVRIVEAILNH 182 H + L + L LA +G +++ + H Sbjct: 118 GHSSVVSFLAPESDLHHRDASGLTPLELARQRGAQNLMDILQGH 161 Score = 45.2 bits (105), Expect = 1e-04, Method: Composition-based stats. Identities = 22/115 (19%), Positives = 40/115 (34%), Gaps = 8/115 (6%) Query: 160 VGDALLLAISKGYVRIVEAILNHP--AFAEGKRLATSPSQSELQQDDFYAYDEDGTRFSH 217 VGD L A ++G V+ V +L+ R + Q + A + S Sbjct: 8 VGDRLSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMMFGSPAVALELLKQGASP 67 Query: 218 DV------TPIILAAHCQEYEIVHTLLRKGARIERPHDYFCKCTECSQKQKHDSF 266 +V +P+ AA + + L+ GA + + ++ H S Sbjct: 68 NVQDASGTSPVHDAARTGFLDTLKVLVEHGADVNALDSTGSLPIHLAIREGHSSV 122 >5ET1-A nrPDB Length = 353 Score = 56.3 bits (134), Expect = 5e-08, Method: Composition-based stats. Identities = 34/174 (19%), Positives = 61/174 (35%), Gaps = 15/174 (8%) Query: 104 AAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLAVANEHLEITELLLK------KENL 157 AA G++P ++ +L + VN G L LA HLE+T+ L++ Sbjct: 146 AAAKGDLPSLK-LLVGHYPEGVNAQTNNGATPLYLACQEGHLEVTKYLVQECSADPHLRA 204 Query: 158 SRVGDALLLAISKGYVRIVEAILNHPAFAEGKR-----LATSPSQSELQQDDFYAYDEDG 212 L A G+ ++ +++ + ++ A + S G Sbjct: 205 QDGMTPLHAAAQMGHNPVLVWLVSFADVSFSEQDHDGATAMHFAASRGHTKVLSWLLLHG 264 Query: 213 TRFSHDV---TPIILAAHCQEYEIVHTLLRKGARIERPHDYFCKCTECSQKQKH 263 S D+ TP+ AA E E L GA ++ + ++ H Sbjct: 265 AEISQDLWGGTPLHDAAENGELECCQILAVNGAGLDVRDHDGYTAADLAEFNGH 318 Score = 52.9 bits (125), Expect = 6e-07, Method: Composition-based stats. Identities = 31/181 (17%), Positives = 59/181 (32%), Gaps = 20/181 (11%) Query: 104 AAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLAVANEHLEITELLLKKEN------L 157 AA G + +R ++EE V+ G A A +L + LL + Sbjct: 44 AARSGKLHCLRYLVEEVALPAVSRARN-GATPAHDAAATGYLSCLQWLLTQGGCRVQEKD 102 Query: 158 SRVGDALLLAISKGYVRIVEAILNHPAFAEGKRLATS--PSQSELQQDDFYAY------- 208 + L LA G+ +V+ +L T P + D + Sbjct: 103 NSGATVLHLAARFGHPDVVKWLLYQGGANSAITTDTGALPIHYAAAKGDLPSLKLLVGHY 162 Query: 209 -DEDGTRFSHDVTPIILAAHCQEYEIVHTLLRKGARIE--RPHDYFCKCTECSQKQKHDS 265 + + ++ TP+ LA E+ L+++ + R D + + H+ Sbjct: 163 PEGVNAQTNNGATPLYLACQEGHLEVTKYLVQECSADPHLRAQD-GMTPLHAAAQMGHNP 221 Query: 266 F 266 Sbjct: 222 V 222 Score = 35.2 bits (79), Expect = 0.16, Method: Composition-based stats. Identities = 19/72 (26%), Positives = 28/72 (38%), Gaps = 8/72 (11%) Query: 79 ANRGPAYMF---NDHSTSLSIE---EERFLDAAEYGNIPVVRKMLEECHSLNVNCVDYMG 132 A+RG + H +S + DAAE G + + + L+V D+ G Sbjct: 249 ASRGHTKVLSWLLLHGAEISQDLWGGTPLHDAAENGELECCQILAVNGAGLDVR--DHDG 306 Query: 133 QNALQLAVANEH 144 A LA N H Sbjct: 307 YTAADLAEFNGH 318 >1WG0-A nrPDB Length = 243 Score = 56.3 bits (134), Expect = 7e-08, Method: Composition-based stats. Identities = 32/169 (18%), Positives = 61/169 (36%), Gaps = 30/169 (17%) Query: 104 AAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLAVANEHLEITELLLKKENLSRVGD- 162 A GN+ VV+ + + ++N + G L LAV + E+++ L++ R+ D Sbjct: 79 ACSVGNLEVVKSLYDRPLKPDLNKITNQGVTCLHLAVGKKWFEVSQFLIENGASVRIKDK 138 Query: 163 ----ALLLAISKGYVRIVEAILNHPAFAEGKRLATSPSQSELQQDDFYAYDEDGTRFSHD 218 L A S G ++++E + A D+ G Sbjct: 139 FNQIPLHRAASVGSLKLIELLCGLGKSA------------------VNWQDKQG------ 174 Query: 219 VTPIILAAHCQEYEIVHTLLRK-GARIERPHDYFCKCTECSQKQKHDSF 266 TP+ A + L+ K GA + + K + + ++ F Sbjct: 175 WTPLFHALAEGHGDAAVLLVEKYGAEYDLVDNKGAKAEDVALNEQVKKF 223 Score = 42.9 bits (99), Expect = 6e-04, Method: Composition-based stats. Identities = 23/148 (15%), Positives = 48/148 (32%), Gaps = 33/148 (22%) Query: 116 MLEECHSLNVNCV-DYMGQNALQLAVANEHLEITELLLKK------ENLSRVG-DALLLA 167 +L + ++N++ D G +A + +LE+ + L + ++ G L LA Sbjct: 55 LLSKMENVNLDDYPDDSGWTPFHIACSVGNLEVVKSLYDRPLKPDLNKITNQGVTCLHLA 114 Query: 168 ISKGYVRIVEAILNHPAFAEGKRLATSPSQSELQQDDFYAYDEDGTRFSHDVTPIILAAH 227 + K + + + ++ + A K D F P+ AA Sbjct: 115 VGKKWFEVSQFLIENGASVRIK-------------DKFNQI------------PLHRAAS 149 Query: 228 CQEYEIVHTLLRKGARIERPHDYFCKCT 255 +++ L G D Sbjct: 150 VGSLKLIELLCGLGKSAVNWQDKQGWTP 177 >6AUN-A nrPDB Length = 752 Score = 56.0 bits (133), Expect = 8e-08, Method: Composition-based stats. Identities = 42/229 (18%), Positives = 77/229 (33%), Gaps = 16/229 (6%) Query: 97 EEERFLDAAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLAVANEHLEITELLLKKEN 156 + E A G+ V ++L + S +N V+ G L LA E+ +LL Sbjct: 185 KGETAFHYAVQGDNSQVLQLLGKNASAGLNQVNKQGLTPLHLACQMGKQEMVRVLLLCNA 244 Query: 157 LSRV----GDALLLAISKGYVRIVEAILNHPAF---AEGKRLATSPSQSELQQDDFYAYD 209 V G + A+ E I++ + ++ R SP + Sbjct: 245 RCNVMGPSGFPIHTAMKFSQKGCAEMIISMDSSQIHSKDPRYGASPLHWAKNAEMARMLL 304 Query: 210 EDG----TRFSHDVTPIILAAHCQEYEIVHTLLRKGARIERPHDYFCKCTECSQKQKHDS 265 + G + + T + +A ++ V LL GA P ++ + + + Sbjct: 305 KRGCDVDSTSAAGNTALHVAVMRNRFDCVMVLLTYGANAGTPGEHGNTPLHLAISKDNME 364 Query: 266 FSHSRSRINAYKGLASPAYLSLSSEDPVMTALELSNELAVLANIEKEFK 314 + A +P E P A ++S +L L I + K Sbjct: 365 MIKALIVFGAEV--DTPNDFG---ETPAFMASKISKQLQDLMPISRARK 408 Score = 44.0 bits (102), Expect = 3e-04, Method: Composition-based stats. Identities = 28/129 (21%), Positives = 36/129 (27%), Gaps = 17/129 (13%) Query: 133 QNALQLAVANE------HLEITELLLKKENLSRVGDALLLAISKGYVRI-VEAI------ 179 LAV H I EN L LA KG I VE + Sbjct: 120 WTVTHLAVELGIRECFHHSRIISCANSTENEEGC-TPLHLACRKGDSEILVELVQYCHAQ 178 Query: 180 ---LNHPAFAEGKRLATSPSQSELQQDDFYAYDEDGTRFSHDVTPIILAAHCQEYEIVHT 236 ++ + LQ A +TP+ LA + E+V Sbjct: 179 MDVTDNKGETAFHYAVQGDNSQVLQLLGKNASAGLNQVNKQGLTPLHLACQMGKQEMVRV 238 Query: 237 LLRKGARIE 245 LL AR Sbjct: 239 LLLCNARCN 247 >4QY5-A nrPDB Length = 263 Score = 55.6 bits (132), Expect = 9e-08, Method: Composition-based stats. Identities = 14/65 (21%), Positives = 27/65 (41%), Gaps = 8/65 (12%) Query: 272 RINAYKG-----LASPAYL-SLSSED--PVMTALELSNELAVLANIEKEFKNDYRKLSMQ 323 ++ A G L S L S E+ P+ + ++ AVL+ ++ + R++ Sbjct: 14 QLGARVGYIELDLNSGKILESFRPEERFPLTSTFKVLLCGAVLSRVDAGQEQLGRRIHYS 73 Query: 324 CKDFV 328 D V Sbjct: 74 QNDLV 78 >3EHQ-A nrPDB Length = 222 Score = 55.2 bits (131), Expect = 1e-07, Method: Composition-based stats. Identities = 29/100 (29%), Positives = 50/100 (50%), Gaps = 8/100 (8%) Query: 101 FLDAAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLAVANEHLEITELL-----LKKE 155 +AA+ GN+ +R+ L+ + + VN +D G AL A H +I E+L ++ Sbjct: 77 LHEAAKRGNLSWLRECLD--NRVGVNGLDKAGSTALYWACHGGHKDIVEMLFTQPNIELN 134 Query: 156 NLSRVGD-ALLLAISKGYVRIVEAILNHPAFAEGKRLATS 194 +++GD AL A KGY IV+ +L A + + + Sbjct: 135 QQNKLGDTALHAAAWKGYADIVQLLLAKGARTDLRNIEKK 174 Score = 39.4 bits (90), Expect = 0.008, Method: Composition-based stats. Identities = 31/169 (18%), Positives = 53/169 (31%), Gaps = 38/169 (22%) Query: 118 EECHSLNVNCVDYMGQNALQLAVANEHLE-ITELLLKK----ENLSRVGDALLLAISKGY 172 E+ S++ N L A +L + E L + AL A G+ Sbjct: 68 EQAESID---------NPLHEAAKRGNLSWLRECLDNRVGVNGLDKAGSTALYWACHGGH 118 Query: 173 VRIVEAILNHPAFAEGKRLATSPSQSELQQDDFYAYDEDGTRFSHDVTPIILAAHCQEYE 232 IVE + P + ++ G T + AA + Sbjct: 119 KDIVEMLFTQP------------------NIELNQQNKLGD------TALHAAAWKGYAD 154 Query: 233 IVHTLLRKGARIERPHDYFCKCTECSQKQKHDSFSHSRSRINAYKGLAS 281 IV LL KGAR + + + + S + +A + L++ Sbjct: 155 IVQLLLAKGARTDLRNIEKKLAFDMATNAACASLLKKKQGTDAVRTLSN 203 >1BD8-A nrPDB Length = 156 Score = 55.2 bits (131), Expect = 1e-07, Method: Composition-based stats. Identities = 32/174 (18%), Positives = 60/174 (34%), Gaps = 33/174 (18%) Query: 98 EERFLDAAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLAVANEHLEITELLLKKENL 157 +R AA G++ VR++L ++ + ++ G+ ALQ+ + I LLK+ Sbjct: 3 GDRLSGAAARGDVQEVRRLLHR-ELVHPDALNRFGKTALQVMMF-GSTAIALELLKQGAS 60 Query: 158 SRVGD-----ALLLAISKGYVRIVEAILNHPAFAEGKRLATSPSQSELQQDDFYAYDEDG 212 V D + A G++ ++ ++ H A D D G Sbjct: 61 PNVQDTSGTSPVHDAARTGFLDTLKVLVEHGA-------------------DVNVPDGTG 101 Query: 213 TRFSHDVTPIILAAHCQEYEIVHTLLRKGARIERPHDYFCKCTECSQKQKHDSF 266 PI LA +V L + + + R E + ++ Sbjct: 102 AL------PIHLAVQEGHTAVVSFLAAE-SDLHRRDARGLTPLELALQRGAQDL 148 Score = 54.4 bits (129), Expect = 2e-07, Method: Composition-based stats. Identities = 23/104 (22%), Positives = 41/104 (39%), Gaps = 10/104 (9%) Query: 87 FNDHSTSLSIEEER----FLDAAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLAVAN 142 S ++++ DAA G + ++ ++E H +VN D G + LAV Sbjct: 54 LLKQGASPNVQDTSGTSPVHDAARTGFLDTLKVLVE--HGADVNVPDGTGALPIHLAVQE 111 Query: 143 EHLEITELLLK----KENLSRVGDALLLAISKGYVRIVEAILNH 182 H + L +R L LA+ +G +V+ + H Sbjct: 112 GHTAVVSFLAAESDLHRRDARGLTPLELALQRGAQDLVDILQGH 155 Score = 54.0 bits (128), Expect = 3e-07, Method: Composition-based stats. Identities = 24/148 (16%), Positives = 54/148 (36%), Gaps = 7/148 (4%) Query: 67 RQTILREKGRRLANRGPAYMFNDHSTSLSIEEERFLDAAEYGNIPVVRKMLEECHSLNVN 126 R + +G R + H +L+ + L +G+ + ++L++ + N Sbjct: 5 RLSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMMFGSTAIALELLKQ--GASPN 62 Query: 127 CVDYMGQNALQLAVANEHLEITELLLKKENLSRVGD-----ALLLAISKGYVRIVEAILN 181 D G + + A L+ ++L++ V D + LA+ +G+ +V + Sbjct: 63 VQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSFLAA 122 Query: 182 HPAFAEGKRLATSPSQSELQQDDFYAYD 209 +P + LQ+ D Sbjct: 123 ESDLHRRDARGLTPLELALQRGAQDLVD 150 Score = 46.3 bits (108), Expect = 7e-05, Method: Composition-based stats. Identities = 22/116 (18%), Positives = 41/116 (35%), Gaps = 8/116 (6%) Query: 159 RVGDALLLAISKGYVRIVEAILNHP--AFAEGKRLATSPSQSELQQDDFYAYDEDGTRFS 216 R GD L A ++G V+ V +L+ R + Q + A + S Sbjct: 1 RAGDRLSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMMFGSTAIALELLKQGAS 60 Query: 217 HDV------TPIILAAHCQEYEIVHTLLRKGARIERPHDYFCKCTECSQKQKHDSF 266 +V +P+ AA + + L+ GA + P + ++ H + Sbjct: 61 PNVQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAV 116 >5D68-A nrPDB Length = 486 Score = 52.5 bits (124), Expect = 8e-07, Method: Composition-based stats. Identities = 28/156 (17%), Positives = 54/156 (34%), Gaps = 15/156 (9%) Query: 104 AAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLAVANEHLEITELLLKKENLS----- 158 +A G+ ++ ++L +VN +D + A +E T +LL+K + Sbjct: 45 SACEGDSELLSRLL--SERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNLLN 102 Query: 159 -RVGDALLLAISKGYVRIVEAILNHPA-----FAEGKRLATSPSQSELQQDDFYAYDEDG 212 ++ L A G+ IV+ +LNHP + R + + Q + A Sbjct: 103 GQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQNNWEEAAKLLK 162 Query: 213 TRFSHDVTPIILAAHCQEYEIVHTLLRKGARIERPH 248 + + + Y V L+ G Sbjct: 163 EAINKPYEKVRIYRMDGSYRSVE--LKHGNNTTVQQ 196 >3OPP-A nrPDB Length = 286 Score = 51.7 bits (122), Expect = 1e-06, Method: Composition-based stats. Identities = 19/79 (24%), Positives = 35/79 (44%), Gaps = 8/79 (10%) Query: 258 SQKQKHDSFSHSRSRINAYKG-----LASPAYLSLSSED---PVMTALELSNELAVLANI 309 + Q + S S+++ G LAS L+ D P+M+ ++ AVLA + Sbjct: 21 ASPQPLEQIKLSESQLSGRVGMIEMDLASGRTLTAWRADERFPMMSTFKVVLCGAVLARV 80 Query: 310 EKEFKNDYRKLSMQCKDFV 328 + + RK+ + +D V Sbjct: 81 DAGDEQLERKIHYRQQDLV 99 >4OT9-A nrPDB Length = 359 Score = 51.3 bits (121), Expect = 2e-06, Method: Composition-based stats. Identities = 41/221 (18%), Positives = 76/221 (34%), Gaps = 39/221 (17%) Query: 104 AAEYGNIPVVRKMLEECHSLN----VNCVDYMGQNALQLAVANEHLEITELLLKKENLSR 159 A +G V+ +++ H VN +++ Q L LAV + LL+ Sbjct: 89 AIIHGQTSVIEQIVYVIHHAQDLGVVNLTNHLHQTPLHLAVITGQTSVVSFLLRVGADPA 148 Query: 160 VGD-----ALLLAIS--KGYVRIVEAILNHPAFAEGKRLATSPSQSELQQDDFYAYDEDG 212 + D A+ LA+ G ++ A+L A A + L + Sbjct: 149 LLDRHGDSAMHLALRAGAGAPELLRALLQSGAPAVPQLLHMPDFEG-------------- 194 Query: 213 TRFSHDVTPIILAAHCQEYEIVHTLLRKGARIERPHDYFCKCTECSQKQKHD------SF 266 + P+ LA + E + L+ GA +E + + + Sbjct: 195 ------LYPVHLAVRARSPECLDLLVDSGAEVEATERQGGRTALHLATEMEELGLVTHLV 248 Query: 267 SHSRSRINAYK-GLASPAYLSLSSEDPVMTALELSNELAVL 306 + R+ +NA +P +L+ P +T L L A + Sbjct: 249 TKLRANVNARTFAGNTPLHLAAGLGYPTLTRL-LLKAGADI 288 Score = 45.2 bits (105), Expect = 1e-04, Method: Composition-based stats. Identities = 17/80 (21%), Positives = 28/80 (35%), Gaps = 6/80 (7%) Query: 86 MFNDHSTSLSIEEER-----FLDAAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLAV 140 + D + E + A E + +V ++ + NVN + G L LA Sbjct: 212 LLVDSGAEVEATERQGGRTALHLATEMEELGLVTHLVTKLR-ANVNARTFAGNTPLHLAA 270 Query: 141 ANEHLEITELLLKKENLSRV 160 + +T LLLK Sbjct: 271 GLGYPTLTRLLLKAGADIHA 290 Score = 44.4 bits (103), Expect = 2e-04, Method: Composition-based stats. Identities = 30/150 (20%), Positives = 48/150 (32%), Gaps = 17/150 (11%) Query: 104 AAEYGNIPVVRKMLEECHSLNVNCVDYMG-QNALQLAVANEHLEITELLLKK-----ENL 157 A + + +++ V + G + AL LA E L + L+ K Sbjct: 201 AVRARSPECLDLLVDS--GAEVEATERQGGRTALHLATEMEELGLVTHLVTKLRANVNAR 258 Query: 158 SRVGD-ALLLAISKGYVRIVEAILNHP----AFAEGKRLATSPSQSELQQDDFYAYDEDG 212 + G+ L LA GY + +L A E + D ++D Sbjct: 259 TFAGNTPLHLAAGLGYPTLTRLLLKAGADIHAENEEPLCPLPSPPTSDSDSDSEGPEKDT 318 Query: 213 TRFSHDVTPIILAAHCQEYEIVHTLLRKGA 242 TP+ L + V TLL A Sbjct: 319 RSSFRGHTPLDLTCSTK----VKTLLLNAA 344 >6AYG-A nrPDB Length = 558 Score = 48.6 bits (114), Expect = 1e-05, Method: Composition-based stats. Identities = 17/141 (12%), Positives = 53/141 (37%), Gaps = 8/141 (5%) Query: 597 LYAIAVVLSFSRIAYILPANESFGPLQISLGRTVKDIFKFMVIFIMVFVAFMIGMFNLYS 656 L + +L + + L + L ++L + ++ +F M+++ + + + Sbjct: 381 LLGTSTMLVWLGVIRYLGFFAKYNLLILTLQAALPNVIRFCCCAAMIYLGYCFCGWIVLG 440 Query: 657 YYIGAKQNEAFTTVEESFKTLFWAIFGLSEVKSVVINYNHKFIENIGYVLYGVYNVTMVI 716 + + V E +L ++ + K + +Y+ + Sbjct: 441 --PYHDKFRSLNMVSECLFSL----INGDDMFATFAKMQQKSYLVWLFSRIYLYSFISLF 494 Query: 717 V--LLNMLIAMINSSFQEIED 735 + +L++ IA+I +++ I+ Sbjct: 495 IYMILSLFIALITDTYETIKQ 515 >1D9S-A nrPDB Length = 136 Score = 48.6 bits (114), Expect = 1e-05, Method: Composition-based stats. Identities = 18/90 (20%), Positives = 36/90 (40%), Gaps = 9/90 (10%) Query: 101 FLDAAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLAVANEHLEITELLLKKENLSRV 160 AA G + VR++LE + N ++ G+ +Q+ + ++ ELLL Sbjct: 16 LATAAARGQVETVRQLLEA--GADPNALNRFGRRPIQV-MMMGSAQVAELLLLHGAEPNC 72 Query: 161 GD------ALLLAISKGYVRIVEAILNHPA 184 D + A +G++ + + A Sbjct: 73 ADPATLTRPVHDAAREGFLDTLVVLHRAGA 102 >3T9K-A nrPDB Length = 390 Score = 47.5 bits (111), Expect = 2e-05, Method: Composition-based stats. Identities = 20/101 (19%), Positives = 34/101 (33%), Gaps = 13/101 (12%) Query: 90 HSTSLS------IEEERFLDAAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLAVANE 143 H ++ + A ++ +L+ + NVN D G+ L A Sbjct: 222 HGADVNWVNGGQDNATPLIQATAANSLLACEFLLQ--NGANVNQADSAGRGPLHHATILG 279 Query: 144 HLEITELLLKKEN-----LSRVGDALLLAISKGYVRIVEAI 179 H + L LK+ S D L +A+ IV + Sbjct: 280 HTGLACLFLKRGADLGARDSEGRDPLTIAMETANADIVTLL 320 Score = 43.2 bits (100), Expect = 5e-04, Method: Composition-based stats. Identities = 29/138 (21%), Positives = 41/138 (29%), Gaps = 33/138 (23%) Query: 108 GNIPVVRKMLEE-CHSLNVNCVD--YMGQNALQLAVANEHLEITELLLKKENLSRVGD-- 162 G+ P + M + H +VN V+ L A A L E LL+ D Sbjct: 208 GHPPSLPTMADALAHGADVNWVNGGQDNATPLIQATAANSLLACEFLLQNGANVNQADSA 267 Query: 163 ---ALLLAISKGYVRIVEAILNHPAFAEGKRLATSPSQSELQQDDFYAYDEDGTRFSHDV 219 L A G+ + L A D A D +G Sbjct: 268 GRGPLHHATILGHTGLACLFLKRGA-------------------DLGARDSEGRD----- 303 Query: 220 TPIILAAHCQEYEIVHTL 237 P+ +A +IV L Sbjct: 304 -PLTIAMETANADIVTLL 320 Score = 32.8 bits (73), Expect = 0.70, Method: Composition-based stats. Identities = 26/146 (17%), Positives = 43/146 (29%), Gaps = 13/146 (8%) Query: 182 HPAFAEGKRLATSPSQSELQQDDFYAYDEDGTRFSHD-VTPIILAAHCQEYEIVHTLLRK 240 HP + PS + + D + D TP+I A LL+ Sbjct: 198 HPGALLFRASGHPPSLPTMADALAHGADVNWVNGGQDNATPLIQATAANSLLACEFLLQN 257 Query: 241 GARIERPHDYFCKCTECSQKQKHDSFSHSRSRINAYKGLASPAYLSLSSEDPVMTALELS 300 GA + + + H + + +G A S DP+ A+E + Sbjct: 258 GANVNQADSAGRGPLHHATILGHTGLAC----LFLKRGADLGARDS-EGRDPLTIAMETA 312 Query: 301 NE-------LAVLANIEKEFKNDYRK 319 N LA + E + Sbjct: 313 NADIVTLLRLAKMREAEAAQGQAGDE 338 >2A5E-A nrPDB Length = 156 Score = 47.5 bits (111), Expect = 3e-05, Method: Composition-based stats. Identities = 19/100 (19%), Positives = 36/100 (36%), Gaps = 9/100 (9%) Query: 91 STSLSIEEERFLDAAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLAVANEHLEITEL 150 +S+ + AA G + VR +LE N + G+ +Q+ + + EL Sbjct: 6 GSSMEPSADWLATAAARGRVEEVRALLEA--GALPNAPNSYGRRPIQV-MMMGSARVAEL 62 Query: 151 LLKKENLSRVGD------ALLLAISKGYVRIVEAILNHPA 184 LL D + A +G++ + + A Sbjct: 63 LLLHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGA 102 >5DND-A nrPDB Length = 588 Score = 47.1 bits (110), Expect = 4e-05, Method: Composition-based stats. Identities = 27/108 (25%), Positives = 40/108 (37%), Gaps = 12/108 (11%) Query: 87 FNDHSTSLSIE---EERFLD-AAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLAVAN 142 + + L ++ + L AA G VV +L ++VN D G + L LAV Sbjct: 441 LMELGSDLRLKDSNGQTLLHVAARNGRDGVVTMLLHR--GMDVNARDRDGLSPLLLAVQG 498 Query: 143 EHLEITELLLKKEN------LSRVGDALLLAISKGYVRIVEAILNHPA 184 H E LL K L G L S+ + ++A A Sbjct: 499 RHRECIRLLRKAGACLSPQDLKDAGTELCRLASRADMEGLQAWGQAGA 546 >3LJN-A nrPDB Length = 364 Score = 47.1 bits (110), Expect = 4e-05, Method: Composition-based stats. Identities = 32/164 (19%), Positives = 59/164 (35%), Gaps = 16/164 (9%) Query: 99 ERFLDAAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLAVANEHLEITELLLKKE--- 155 E+ AA G VR+++E ++ + G AL LA ++ + L Sbjct: 22 EKIHVAARKGQTDEVRRLIET--GVSPTIQNRFGCTALHLACKFGCVDTAKYLASVGEVH 79 Query: 156 NLSRVGDALLLAISKGYVRIVEAILNHPAFAEGKRLATSPSQSELQQDDFYAYDEDGTRF 215 +L + LA+ +V A++ EG + +S L + D +E G+ Sbjct: 80 SLWHGQKPIHLAVMANKTDLVVALV------EGAKERGQMPESLLNECDEREVNEIGSHV 133 Query: 216 SH--DVTPIILAAHCQ--EYEIVHTLLRKGARIERPHDYFCKCT 255 H T + E++ L++ GA D + Sbjct: 134 KHCKGQTALHWCVGLGPEYLEMIKILVQLGAS-PTAKDKADETP 176 >3UI2-A nrPDB Length = 244 Score = 47.1 bits (110), Expect = 4e-05, Method: Composition-based stats. Identities = 27/169 (15%), Positives = 59/169 (34%), Gaps = 21/169 (12%) Query: 94 LSIEEERFLDAAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLAVANEHLEITELLLK 153 +S E + AA + + ++LE+ +V+ VD G+ AL + LL + Sbjct: 42 VSEYETPWWTAARKADEQALSQLLEDR---DVDAVDENGRTALLFVAGLGSDKCVRLLAE 98 Query: 154 KENLSRVGD------ALLLAISKGYVRIVEAILNHPAFAEGKRLATSPSQSELQQDDFYA 207 D AL +A +VEA++ A E + + ++ Sbjct: 99 AGADLDHRDMRGGLTALHMAAGYVRPEVVEALVELGADIEVEDERGLTALELAREI---- 154 Query: 208 YDEDGTRFSHDVTPIILAAHCQEYEIVHTL---LRKGARIERPHDYFCK 253 + + P+ ++++ L + + A ++ + K Sbjct: 155 -----LKTTPKGNPMQFGRRIGLEKVINVLEGQVFEYAEVDEIVEKRGK 198 >3DEO-A nrPDB Length = 183 Score = 45.9 bits (107), Expect = 9e-05, Method: Composition-based stats. Identities = 25/150 (16%), Positives = 52/150 (34%), Gaps = 18/150 (12%) Query: 94 LSIEEERFLDAAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLAVANEHLEITELLLK 153 +S E + AA + + ++LE+ +V+ VD G+ AL + LL + Sbjct: 41 VSEYETPWWTAARKADEQALSQLLEDR---DVDAVDENGRTALLFVAGLGSDKCVRLLAE 97 Query: 154 KENLSRVGD------ALLLAISKGYVRIVEAILNHPAFAEGKRLATSPSQSELQQDDFYA 207 D AL +A +VEA++ A E + + ++ Sbjct: 98 AGADLDHRDMRGGLTALHMAAGYVRPEVVEALVELGADIEVEDERGLTALELAREI---- 153 Query: 208 YDEDGTRFSHDVTPIILAAHCQEYEIVHTL 237 + + P+ ++++ L Sbjct: 154 -----LKTTPKGNPMQFGRRIGLEKVINVL 178 >6EMK-G nrPDB Length = 426 Score = 45.6 bits (106), Expect = 1e-04, Method: Composition-based stats. Identities = 29/164 (17%), Positives = 56/164 (34%), Gaps = 28/164 (17%) Query: 100 RFLDAAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLAVANEHLEITELLLKKENLS- 158 R +A GN+ +V+++L L N G ++L A + I L++ + Sbjct: 8 RLREAIIEGNLLIVKRLLRRNPDLLTNIDSENGWSSLHYASYHGRYLICVYLIQLGHDKH 67 Query: 159 ------RVGDALLLAISKGYVRIVEAIL-------NHPAFAEGKRLATSPSQSELQ---- 201 + + LA+ KG+ + + +L NH + + Q Sbjct: 68 ELIKTFKGNTCVHLALMKGHEQTLHLLLQQFPRFINHRGENGRAPIHIACMNDYYQCLSL 127 Query: 202 ----QDDFYAYDEDGTRFSHDVTPIILAAHCQEYEIVHTLLRKG 241 D + D +G TP+ + + LL +G Sbjct: 128 LIGVGADLWVMDTNGD------TPLHVCLEYGSISCMKMLLNEG 165 >5U0K-A nrPDB Length = 141 Score = 44.0 bits (102), Expect = 3e-04, Method: Composition-based stats. Identities = 17/88 (19%), Positives = 39/88 (44%), Gaps = 8/88 (9%) Query: 101 FLDAAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLAVANEHLEITELLLK------K 154 L AA G++ +R+ +++ DY + AL +A A H+E+ + L++ Sbjct: 29 LLFAAYSGDVSALRRFALSA--MDMEQKDYDSRTALHVAAAEGHIEVVKFLIEACKVNPF 86 Query: 155 ENLSRVGDALLLAISKGYVRIVEAILNH 182 L A+ ++ +V+ + ++ Sbjct: 87 AKDRWGNIPLDDAVQFNHLEVVKLLQDY 114 >5U0J-A nrPDB Length = 140 Score = 43.6 bits (101), Expect = 4e-04, Method: Composition-based stats. Identities = 17/102 (16%), Positives = 39/102 (38%), Gaps = 8/102 (7%) Query: 87 FNDHSTSLSIEEERFLDAAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLAVANEHLE 146 + + L AA G++ +R+ +++ DY + AL +A A H+E Sbjct: 14 LVPRGSHMVKSVINLLFAAYTGDVSALRRFALSA--MDMEQRDYDSRTALHVAAAEGHVE 71 Query: 147 ITELLLK------KENLSRVGDALLLAISKGYVRIVEAILNH 182 + + LL+ + A+ G+ + + + + Sbjct: 72 VVKFLLEACKVNPFPKDRWNNTPMDEALHFGHHDVFKILQEY 113 >3RVY-A nrPDB Length = 285 Score = 42.9 bits (99), Expect = 6e-04, Method: Composition-based stats. Identities = 31/164 (18%), Positives = 65/164 (39%), Gaps = 12/164 (7%) Query: 568 KVTLGDNVKYYNLARIKWDPTDPQIISEGL------YAIAVVLSFSRIAYILPANESFGP 621 ++ L V + + W D +++ L + I VL R+ ++ A Sbjct: 77 EIILRIYVHRISFFKDPWSLFDFFVVAISLVPTSSGFEILRVLRVLRLFRLVTAVPQMRK 136 Query: 622 LQISLGRTVKDIFKFMVIFIMVFVAFMIGMFNLYSYYIGAKQNEAFTTVEESFKTLFWAI 681 + +L + + + + + F F I L+ G + E F T+ ESF TLF + Sbjct: 137 IVSALISVIPGMLSVIALMTLFFYIFAIMATQLF----GERFPEWFGTLGESFYTLFQVM 192 Query: 682 FGLSEVKSVVINYNHKFIENIGYVLYGVYNVTMVIVLLNMLIAM 725 S +V + +V + + + V++N+++A+ Sbjct: 193 TLESWSMGIVRPLMEVYP--YAWVFFIPFIFVVTFVMINLVVAI 234 >6N4I-A nrPDB Length = 288 Score = 42.9 bits (99), Expect = 7e-04, Method: Composition-based stats. Identities = 36/212 (16%), Positives = 73/212 (34%), Gaps = 22/212 (10%) Query: 530 FGMLAIFAASFIARFMAFWHASKAQSIIDAND------TLKDLTKVTLGDNVKYYNLARI 583 F I+ FMA H + + T ++ L V + + Sbjct: 32 FTKFIIYLIVLNTLFMAMEHHPMTEEFKNVLAIGNLVFTGIFAIEIILRIYVHRISFFKD 91 Query: 584 KWDPTDPQIISEGLYAIAVV----------LSFSRIAYILPANESFGPLQISLGRTVKDI 633 W D I++ L + + R+ ++ A + +L + + Sbjct: 92 PWSLFDSLIVTLSLVELFLADVEGLSVLRSFRLLRVFRLVTAVPQMRKIVSALISVIPGM 151 Query: 634 FKFMVIFIMVFVAFMIGMFNLYSYYIGAKQNEAFTTVEESFKTLFWAIFGLSEVKSVVIN 693 + + + F F I L+ G + E F T+ ESF TLF + S +V Sbjct: 152 LSVIALMTLFFYIFAIMATQLF----GERFPEWFGTLGESFYTLFQVMTLESWSMGIVRP 207 Query: 694 YNHKFIENIGYVLYGVYNVTMVIVLLNMLIAM 725 + +V + + + V++N+++A+ Sbjct: 208 LMEVYP--YAWVFFIPFIFVVTFVMINLVVAI 237 >4N5Q-A nrPDB Length = 257 Score = 42.9 bits (99), Expect = 7e-04, Method: Composition-based stats. Identities = 35/182 (19%), Positives = 60/182 (32%), Gaps = 30/182 (16%) Query: 98 EERFLDAAEYGNIPVVRKMLEECH-------SLNVNC-------VDYMGQNALQLAVANE 143 ++R A G + +R++L++ L+V G+ L A+ N Sbjct: 4 KKRIFAAVSEGCVEELRELLQDLQDLCRRRRGLDVPDFLMHKLTASDTGKTCLMKALLNI 63 Query: 144 H---LEITELLLKKENLSRVGDALLLAISKGYVRIVEAILNHPAFAEGKRLATSPSQSEL 200 + EI +LL + + D + A + LN A +R + Sbjct: 64 NPNTKEIVRILLAFAEENDILDRFINAEYTEEAYEGQTALN---IAIERRQGDITAVLIA 120 Query: 201 QQDDFYAYDEDGTRFSHDV---------TPIILAAHCQEYEIVHTLLRKGARIERPHDYF 251 D A+ + G F+ TP+ LAA + EIV L+ D Sbjct: 121 AGADVNAHAK-GVFFNPKYQHEGFYFGETPLALAACTNQPEIVQLLMENEQTDITSQDSR 179 Query: 252 CK 253 Sbjct: 180 GN 181 Score = 40.2 bits (92), Expect = 0.005, Method: Composition-based stats. Identities = 34/218 (15%), Positives = 64/218 (29%), Gaps = 55/218 (25%) Query: 76 RRLANRGPAYMFNDHSTSLSIEEE----RFLDAAEYGNIPVVRKMLEECHSLNV------ 125 RR P ++ H + S + + L +VR +L ++ Sbjct: 32 RRRGLDVPDFLM--HKLTASDTGKTCLMKALLNINPNTKEIVRILLAFAEENDILDRFIN 89 Query: 126 ---NCVDYMGQNALQLAVANEHLEITELLLKKENLSRVG-------------------DA 163 Y GQ AL +A+ +IT +L+ Sbjct: 90 AEYTEEAYEGQTALNIAIERRQGDITAVLIAAGADVNAHAKGVFFNPKYQHEGFYFGETP 149 Query: 164 LLLAISKGYVRIVEAILNHP----------------AFAEGKRLATSPSQSELQQDDFYA 207 L LA IV+ ++ + A + + + D Sbjct: 150 LALAACTNQPEIVQLLMENEQTDITSQDSRGNNILHALVTVAEDFKTQNDFVKRMYDMIL 209 Query: 208 Y-----DEDGTRFSHDVTPIILAAHCQEYEIVHTLLRK 240 + + R + +TP+ LAA + EI+ +L + Sbjct: 210 LRSGNWELETMRNNDGLTPLQLAAKMGKAEILKYILSR 247 >2NYJ-A nrPDB Length = 273 Score = 42.1 bits (97), Expect = 0.001, Method: Composition-based stats. Identities = 32/188 (17%), Positives = 60/188 (31%), Gaps = 55/188 (29%) Query: 108 GNIPVVRKMLEECHSLN-----VNC--VD--YMGQNALQLAVANEHLEITELLLKKENLS 158 G + +L+ + VN D Y GQ AL +A+ ++ + LL++ Sbjct: 68 GQNDTIALLLDVARKTDSLKQFVNASYTDSYYKGQTALHIAIERRNMTLVTLLVENGADV 127 Query: 159 RV---GD----------------ALLLAISKGYVRIVEAILNH---PAFAEGKRLATSPS 196 + GD L LA + IV+ +L + PA + + Sbjct: 128 QAAANGDFFKKTKGRPGFYFGELPLSLAACTNQLAIVKFLLQNSWQPADISARDSVGNTV 187 Query: 197 QSELQQDDFYAYDED-------------GTRFSHD-----------VTPIILAAHCQEYE 232 L + D G + +TP+ LAA + Sbjct: 188 LHALVEVADNTVDNTKFVTSMYNEILILGAKLHPTLKLEEITNRKGLTPLALAASSGKIG 247 Query: 233 IVHTLLRK 240 ++ +L++ Sbjct: 248 VLAYILQR 255 >5UQE-A nrPDB Length = 520 Score = 42.1 bits (97), Expect = 0.001, Method: Composition-based stats. Identities = 17/88 (19%), Positives = 37/88 (42%), Gaps = 8/88 (9%) Query: 101 FLDAAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLAVANEHLEITELLLK------K 154 L AA G++ +R+ +++ DY + AL +A A H+E+ + LL+ Sbjct: 421 LLFAAYTGDVSALRRFALSA--MDMEQRDYDSRTALHVAAAEGHVEVVKFLLEACKVNPF 478 Query: 155 ENLSRVGDALLLAISKGYVRIVEAILNH 182 + A+ G+ + + + + Sbjct: 479 PKDRWNNTPMDEALHFGHHDVFKILQEY 506 Score = 29.8 bits (65), Expect = 5.6, Method: Composition-based stats. Identities = 21/141 (14%), Positives = 48/141 (34%), Gaps = 42/141 (29%) Query: 100 RFLDAAEYGNIPVVRK---MLEECHSLNVNCVDYMGQNALQLAVANEHLEITELLLKKEN 156 + LD G V+ +L ++ +V+ + +A+ + ++ Sbjct: 402 KKLDPRREGGDQRVKSVINLLFAAYTGDVSALRRFALSAMDM---------------EQR 446 Query: 157 LSRVGDALLLAISKGYVRIVEAILNHPAFAEGKRLATSPSQSELQQDDFYAYDEDGTRFS 216 AL +A ++G+V +V+ +L E + + + D Sbjct: 447 DYDSRTALHVAAAEGHVEVVKFLL------------------EACKVNPFPKDRWNN--- 485 Query: 217 HDVTPIILAAHCQEYEIVHTL 237 TP+ A H +++ L Sbjct: 486 ---TPMDEALHFGHHDVFKIL 503 >4BSZ-B nrPDB Length = 202 Score = 42.1 bits (97), Expect = 0.001, Method: Composition-based stats. Identities = 25/83 (30%), Positives = 33/83 (39%), Gaps = 13/83 (15%) Query: 104 AAEYGNIPVVRKMLEECHSLN--------VNCVDYMGQNALQLAVANEHLEITELLLKKE 155 AA G+I VR +LE N VN V+ G AL A N L++ +LL Sbjct: 59 AAANGHIETVRYILETVSRANSAEDLKAFVNEVNKTGNTALHWASLNGKLDVVKLLC--- 115 Query: 156 NLSRVGDALLLAISKGYVRIVEA 178 D + G+ I EA Sbjct: 116 -DEYEADPFIRNKF-GHDAIFEA 136 Score = 34.0 bits (76), Expect = 0.28, Method: Composition-based stats. Identities = 22/109 (20%), Positives = 39/109 (35%), Gaps = 19/109 (17%) Query: 90 HSTSLSIEEE-RFLDAAEYGNIPVVRKM---LEECHSLNVNCVDYMGQNALQLAVANEHL 145 HS L E++ + A G++ ++ + L L+ AL +A AN H+ Sbjct: 6 HSEPLDQEDQDTIILDARAGDLDSLKDIFTTLVSPELLSTCKESESDSTALHMAAANGHI 65 Query: 146 EITELLLK---------------KENLSRVGDALLLAISKGYVRIVEAI 179 E +L+ E AL A G + +V+ + Sbjct: 66 ETVRYILETVSRANSAEDLKAFVNEVNKTGNTALHWASLNGKLDVVKLL 114 Score = 32.5 bits (72), Expect = 0.82, Method: Composition-based stats. Identities = 16/89 (17%), Positives = 30/89 (33%), Gaps = 15/89 (16%) Query: 149 ELLLKKENLSRVGDALLLAISKGYVRIVEAILNHPAFAEGKRLATSPSQSELQQDDFYAY 208 ELL + AL +A + G++ V IL + A + Sbjct: 41 ELLSTCKESESDSTALHMAAANGHIETVRYILETVSRANSAEDLKAF---------VNEV 91 Query: 209 DEDGTRFSHDVTPIILAAHCQEYEIVHTL 237 ++ G T + A+ + ++V L Sbjct: 92 NKTGN------TALHWASLNGKLDVVKLL 114 >6NIQ-A nrPDB Length = 267 Score = 42.1 bits (97), Expect = 0.001, Method: Composition-based stats. Identities = 16/76 (21%), Positives = 33/76 (43%), Gaps = 11/76 (14%) Query: 264 DSFSHSRSRINAYKG---------LASPAYLSLSSED--PVMTALELSNELAVLANIEKE 312 D+ + +R+ A G AS + +D P+ + ++ VLA ++++ Sbjct: 5 DALADMCARLEAGSGGRLGVGVLDTASGRMIGHRLDDRFPMCSTFKVLAAGLVLARVDRK 64 Query: 313 FKNDYRKLSMQCKDFV 328 +N R++S D V Sbjct: 65 QENLDRRVSYAKSDLV 80 >5EK0-A nrPDB Length = 296 Score = 40.2 bits (92), Expect = 0.004, Method: Composition-based stats. Identities = 25/122 (20%), Positives = 51/122 (41%), Gaps = 6/122 (4%) Query: 608 RIAYILPANESFGPLQISLGRTVKDIFKFMVIFIMVFVAFMIGMFNLYSYYIGAKQNEAF 667 RI ++ A + +L + + + + + F F I L+ G + E F Sbjct: 134 RILRLVTAVPQMRKIVSALISVIPGMLSVIALMTLFFYIFAIMATQLF----GERFPEWF 189 Query: 668 TTVEESFKTLFWAIFGLSEVKSVVINYNHKFIENIGYVLYGVYNVTMVIVLLNMLIAMIN 727 T+ ESF TLF + S +V + +V + + + V++N+++A+I Sbjct: 190 GTLGESFYTLFQVMTLESWSMGIVRPLMEVYP--YAWVFFIPFIFVVTFVMINLVVAIIV 247 Query: 728 SS 729 + Sbjct: 248 DA 249 >2F37-A nrPDB Length = 251 Score = 39.8 bits (91), Expect = 0.005, Method: Composition-based stats. Identities = 30/165 (18%), Positives = 52/165 (31%), Gaps = 47/165 (28%) Query: 123 LNVNCVD--YMGQNALQLAVANEHLEITELLLKKENLSRVGD------------------ 162 +N C D Y G +AL +A+ L+ +LL++ Sbjct: 84 VNAQCTDDYYRGHSALHIAIEKRSLQCVKLLVENGANVHARACGRFFQKGQGTCFYFGEL 143 Query: 163 ALLLAISKGYVRIVEAILNHPAFAEGKRLATSPSQSELQQDDFYAYD------------- 209 L LA +V +L +P + S + L + + Sbjct: 144 PLSLAACTKQWDVVSYLLENPHQPASLQATDSQGNTVLHALVMISDNSAENIALVTSMYD 203 Query: 210 ---EDGTRFSH-----------DVTPIILAAHCQEYEIVHTLLRK 240 + G R D+TP+ LAA + EI +L++ Sbjct: 204 GLLQAGARLCPTVQLEDIRNLQDLTPLKLAAKEGKIEIFRHILQR 248 >2ETB-A nrPDB Length = 256 Score = 39.4 bits (90), Expect = 0.007, Method: Composition-based stats. Identities = 31/165 (18%), Positives = 50/165 (30%), Gaps = 47/165 (28%) Query: 123 LNVNCVDYM--GQNALQLAVANEHLEITELLLKKENLSR---VGD--------------- 162 +N C D G +AL +A+ L+ +LL++ G Sbjct: 79 VNAQCTDEFYQGHSALHIAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGEL 138 Query: 163 ALLLAISKGYVRIVEAILNHPAFAEGKRLATSPSQSELQQDDFYAYD------------- 209 L LA +V +L +P S + L A + Sbjct: 139 PLSLAACTKQWDVVTYLLENPHQPASLEATDSLGNTVLHALVMIADNSPENSALVIHMYD 198 Query: 210 ---EDGTRFSHDV-----------TPIILAAHCQEYEIVHTLLRK 240 + G R V TP+ LAA + EI +L++ Sbjct: 199 GLLQMGARLCPTVQLEEISNHQGLTPLKLAAKEGKIEIFRHILQR 243 Score = 30.9 bits (68), Expect = 2.8, Method: Composition-based stats. Identities = 17/105 (16%), Positives = 35/105 (33%), Gaps = 2/105 (1%) Query: 140 VANEHLEITELLLKKENLSRVGDALLLAISKGYVRIVEAILNHPAFAEGKRLATSPSQSE 199 V E + E L + N + D+ S G +++A+LN + + Sbjct: 14 VPEELTGLLEYL--RWNSKYLTDSAYTEGSTGKTCLMKAVLNLQDGVNACIMPLLQIDKD 71 Query: 200 LQQDDFYAYDEDGTRFSHDVTPIILAAHCQEYEIVHTLLRKGARI 244 + F + + +A + + V L+ GA + Sbjct: 72 SGNPKPLVNAQCTDEFYQGHSALHIAIEKRSLQCVKLLVENGADV 116 >3W9G-A nrPDB Length = 260 Score = 37.8 bits (86), Expect = 0.024, Method: Composition-based stats. Identities = 27/135 (20%), Positives = 43/135 (31%), Gaps = 12/135 (8%) Query: 100 RFLDAAEYGNIPVVRKMLEECHSLN-----VN----CVDYMGQNALQLAVANEHLEITEL 150 + L G + +L+ +N V Y GQ AL +A+ EL Sbjct: 52 KALLNLSAGRNDTIPILLDIAEKTGNMREFINSPFRDVYYRGQTALHIAIERRCKHYVEL 111 Query: 151 LLKKENLSRV---GDALLLAISKGYVRIVEAILNHPAFAEGKRLATSPSQSELQQDDFYA 207 L++K G GY E L+ A + +++ +Q D Sbjct: 112 LVEKGADVHAQARGRFFQPKDEGGYFYFGELPLSLAACTNQPHIVHYLTENGHKQADLRR 171 Query: 208 YDEDGTRFSHDVTPI 222 D G H + I Sbjct: 172 QDSRGNTVLHALVAI 186 >4LTR-A nrPDB Length = 152 Score = 37.1 bits (84), Expect = 0.035, Method: Composition-based stats. Identities = 27/131 (20%), Positives = 50/131 (38%), Gaps = 9/131 (6%) Query: 620 GPLQISLGRTVKDIFKFMVIFIMVFVAFMIGMFNLYSYYIGAKQNEAFTTVEESFKTLFW 679 GP SL R + I ++ +++F F + L++ E F T+ S TLF Sbjct: 1 GPSSPSLLRAIPGIAWIALLLLVIFYVFAVMGTKLFAQSF----PEWFGTLGASMYTLFQ 56 Query: 680 AIFGLSEVKSVVINYNHKFIENIGYVLYGVYNVTMVIVLLNMLIAMINSSFQEI---EDD 736 + S + + ++ + + + +LN+ I +I S Q +D Sbjct: 57 VMTLESWSMGIARPVIEAYP--WAWIYFVSFILVSSFTVLNLFIGIIIESMQSAGWEAED 114 Query: 737 ADVEWKFARAK 747 A + RA Sbjct: 115 AKRIEQEQRAH 125 >5HW3-A nrPDB Length = 269 Score = 35.5 bits (80), Expect = 0.10, Method: Composition-based stats. Identities = 9/65 (13%), Positives = 23/65 (35%), Gaps = 3/65 (4%) Query: 267 SHSRSRINAY-KGLASPAYLSLSSEDPVM--TALELSNELAVLANIEKEFKNDYRKLSMQ 323 S R+ + S L +++ + + + +LA ++ + R + Sbjct: 17 RRSGGRLGVFAIDTGSGRTLGHRADERFLMCSTFKGLLAAQILARVDSGSERLDRLVHYT 76 Query: 324 CKDFV 328 KD + Sbjct: 77 EKDLI 81 >6C96-A nrPDB Length = 825 Score = 35.2 bits (79), Expect = 0.13, Method: Composition-based stats. Identities = 17/86 (19%), Positives = 36/86 (41%), Gaps = 5/86 (5%) Query: 653 NLYSYYIGAKQ--NEAFTTVEESFKTLFWAIFGLSEVKSVVINYNHKFIENIGYVLYGVY 710 + +Y+ + + F+T+E S LF L+ + V + VY Sbjct: 248 AILGFYLFSTNPSDPYFSTLENSIVNLFVL---LTTANFPDVMMPSYSRNPWSCVFFIVY 304 Query: 711 NVTMVIVLLNMLIAMINSSFQEIEDD 736 + ++N+L+A++ +F +IE Sbjct: 305 LSIELYFIMNLLLAVVFDTFNDIEKH 330 Score = 34.8 bits (78), Expect = 0.17, Method: Composition-based stats. Identities = 45/229 (19%), Positives = 72/229 (31%), Gaps = 26/229 (11%) Query: 516 GPKEYLFELWNMLDFGMLAIFAASFIARFMAFWHASKAQSIIDANDTLKDLTKVTLGDNV 575 GP EYL WN+ DF + A F+ + L+ L + L Sbjct: 499 GPVEYLSSGWNLFDFSVTAF-------AFLGLLALTLNMEPFYFIVVLRPLQLLRLFKLK 551 Query: 576 KYYNLARIKWDPTDPQIISEGLYAIAVVLSFSRIAYILPANESFGPLQISLGRTVKDIFK 635 K Y P++ S GL + SF+ I + N P + TV D ++ Sbjct: 552 KRYRNVLDTMFELLPRMASLGLTLLTFYYSFA-IVGMEFFNGRLTPNCCNTS-TVADAYR 609 Query: 636 FMVIFIMVFVAFMIGMFNLYS---YYIGAKQN--EAFTTVEESFKTLFWAIFGLSEVKSV 690 F + +G YY+ N +F T+ E W I V Sbjct: 610 F--------INHTVGNKTKVEEGYYYLNNFDNILNSFVTLFELTVVNNWYIIMEG----V 657 Query: 691 VINYNHKFIENIGYVLYGVYNVTMVIVLLNMLIAMINSSFQEIEDDADV 739 +H V +IV + + ++ D++V Sbjct: 658 TSQTSHWSRLYFMTFYIVTMVVMTIIVAFILEAFVFRMNYSRKSQDSEV 706 >3LVQ-E nrPDB Length = 497 Score = 33.6 bits (75), Expect = 0.36, Method: Composition-based stats. Identities = 21/99 (21%), Positives = 36/99 (36%), Gaps = 10/99 (10%) Query: 91 STSLSIEEERFL----DAAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLAVANEHLE 146 EE L A ++P+V +++ L+ D G AL A + Sbjct: 164 GPDAQAPEELVLHLAVKVANQASLPLVDFIIQNGGHLDAKAAD--GNTALHYAALYNQPD 221 Query: 147 ITELLLKK----ENLSRVGDALLLAISKGYVRIVEAILN 181 +LLLK ++ G+ L K + + E +L Sbjct: 222 CLKLLLKGRALVGTVNEAGETALDIARKKHHKECEELLE 260 >2B0O-E nrPDB Length = 301 Score = 33.6 bits (75), Expect = 0.36, Method: Composition-based stats. Identities = 21/99 (21%), Positives = 36/99 (36%), Gaps = 10/99 (10%) Query: 91 STSLSIEEERFL----DAAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLAVANEHLE 146 EE L A ++P+V +++ L+ D G AL A + Sbjct: 183 GPDAQAPEELVLHLAVKVANQASLPLVDFIIQNGGHLDAKAAD--GNTALHYAALYNQPD 240 Query: 147 ITELLLKK----ENLSRVGDALLLAISKGYVRIVEAILN 181 +LLLK ++ G+ L K + + E +L Sbjct: 241 CLKLLLKGRALVGTVNEAGETALDIARKKHHKECEELLE 279 >5HKD-A nrPDB Length = 152 Score = 33.6 bits (75), Expect = 0.46, Method: Composition-based stats. Identities = 23/112 (20%), Positives = 44/112 (39%), Gaps = 6/112 (5%) Query: 620 GPLQISLGRTVKDIFKFMVIFIMVFVAFMIGMFNLYSYYIGAKQNEAFTTVEESFKTLFW 679 GP SL R + I ++ +++F F + L++ E F T+ S TLF Sbjct: 1 GPSSPSLLRAIPGIAWIALLLLVIFYVFAVMGTKLFAQSF----PEWFGTLGASMYTLFQ 56 Query: 680 AIFGLSEVKSVVINYNHKFIENIGYVLYGVYNVTMVIVLLNMLIAMINSSFQ 731 + S + + ++ + + + +LN+ I +I S Q Sbjct: 57 VMTLESWSMGIARPVIEAYP--WAWIYFVSFILVSSFTVLNLFIGIIIESMQ 106 >4DX2-A nrPDB Length = 259 Score = 33.6 bits (75), Expect = 0.46, Method: Composition-based stats. Identities = 24/135 (17%), Positives = 42/135 (31%), Gaps = 12/135 (8%) Query: 100 RFLDAAEYGNIPVVRKMLEECHSLN-----VN----CVDYMGQNALQLAVANEHLEITEL 150 + L G + +L+ +N + Y GQ AL +A+ EL Sbjct: 50 KALLNLSNGRNDTIPVLLDIAERTGNMREFINSPFRDIYYRGQTALHIAIERRCKHYVEL 109 Query: 151 LLKKENLSRV---GDALLLAISKGYVRIVEAILNHPAFAEGKRLATSPSQSELQQDDFYA 207 L+ + G GY E L+ A + +++ ++ D Sbjct: 110 LVAQGADVHAQARGRFFQPKDEGGYFYFGELPLSLAACTNQPHIVNYLTENPHKKADMRR 169 Query: 208 YDEDGTRFSHDVTPI 222 D G H + I Sbjct: 170 QDSRGNTVLHALVAI 184 >4DXW-A nrPDB Length = 229 Score = 32.8 bits (73), Expect = 0.74, Method: Composition-based stats. Identities = 24/161 (14%), Positives = 59/161 (36%), Gaps = 15/161 (9%) Query: 582 RIKWDPTDPQIISEGLYAIAVVLSFS--------RIAYILPANESFGPLQISLGRTVKDI 633 + W+ D I++ L I SF R+ ++ + ++ +V+ + Sbjct: 74 KSGWNIFDTVIVAISLIPIPNNSSFLVLRLLRIFRVLRLISVIPELKQIIEAILESVRRV 133 Query: 634 FKFMVIFIMVFVAFMIGMFNLYSYYIGAKQNEAFTTVEESFKTLFWAIFGLSEVKSVVIN 693 F ++ ++ + L+ G + + S TLF L+ + Sbjct: 134 FFVSLLLFIILYIYATMGAILF----GNDDPSRWGDLGISLITLFQV---LTLSSWETVM 186 Query: 694 YNHKFIENIGYVLYGVYNVTMVIVLLNMLIAMINSSFQEIE 734 + I +V + + + I +LN++IA++ + + Sbjct: 187 LPMQEIYWWSWVYFFSFIIICSITILNLVIAILVDVVIQKK 227 >6GC1-A nrPDB Length = 579 Score = 32.5 bits (72), Expect = 0.81, Method: Composition-based stats. Identities = 31/143 (21%), Positives = 48/143 (33%), Gaps = 13/143 (9%) Query: 155 ENLSRVGDALLLAISKGYVRIVEAILNHPAFAEGKRLATSPSQSELQQDDFYAYDEDGTR 214 N+ V D I K + + + A + QQ +D Sbjct: 295 NNIIYVADTENHLIRKIDLEAEKV--STVAGIGIQGTDKEGGAKGEQQPISSPWDVVFGT 352 Query: 215 FSHDVT--PIILAAHCQEYEIVHTLLRKGARIERPHDYFCKCTECSQKQKHDSFSHSRSR 272 +V I+ A ++I LL G ++ C + ++ R Sbjct: 353 SGSEVQRGDILWIAMAGTHQIWALLLDSGKLPKKNELTKGTCLRFAGSGNEEN------R 406 Query: 273 INAY---KGLASPAYLSLSSEDP 292 NAY G A P+ LSL+SEDP Sbjct: 407 NNAYPHKAGFAQPSGLSLASEDP 429 >4BGN-A nrPDB Length = 298 Score = 32.5 bits (72), Expect = 0.85, Method: Composition-based stats. Identities = 32/233 (13%), Positives = 76/233 (32%), Gaps = 41/233 (17%) Query: 511 EIWTQGPKEYLFELWNMLDFGMLAIFAASFIARFMAFWHASKAQSIIDANDTLKDLTKVT 570 E + + Y + + ++D +L +F A I + +A Sbjct: 46 ETYPGIYQPY-QDWFYLIDRMILWVFTAEIILKLVA------------------------ 80 Query: 571 LGDNVKYYNLARIKWDPTDPQIISEGLYAIAVVLSFSRIAYILPANESFGPLQISLGRTV 630 ++ + W+ D I++ G + + + SL R V Sbjct: 81 TRPRYHFF---KDSWNVFDFLIVASGHLFVGAQFVTVLRVLRVLRLLRAVTVIPSLRRLV 137 Query: 631 KDIFK-------FMVIFIMVFVAFMIGMFNLYSYYIGAKQNEAFTTVEESFKTLFWAIFG 683 + M++ ++F F + M + E F ++ S TLF + Sbjct: 138 SALLYTIPSLGNIMLLMGLIFYIFGV-MGTFLFRDVAP---EYFGSLHLSLITLFQVVTL 193 Query: 684 LSEVKSVVINYNHKFIENIGYVLYGVYNVTMVIVLLNMLIAMINSSFQEIEDD 736 S ++ + ++ + + + V+ N+ + +I S+ + E + Sbjct: 194 ESWASGIMRPIMAE--VFWSWIYFVAFILVGTFVIFNLFVGVIVSNVERAETE 244 >5EUA-A nrPDB Length = 265 Score = 32.1 bits (71), Expect = 1.3, Method: Composition-based stats. Identities = 8/30 (26%), Positives = 14/30 (46%) Query: 293 VMTALELSNELAVLANIEKEFKNDYRKLSM 322 + + +L VL+ I+ +N RKL Sbjct: 42 MCSTFKLPLAALVLSRIDAGEENPERKLHY 71 >6EM5-I nrPDB Length = 663 Score = 31.7 bits (70), Expect = 1.4, Method: Composition-based stats. Identities = 13/46 (28%), Positives = 27/46 (58%) Query: 873 KESDEVNEGELKEIKQDISSLRYELLEEKSQNTEDLAELIRKLGER 918 KE + E ++ ++K+DI+ L +++EE +NT L L + + + Sbjct: 124 KEDEPDTEEKILQLKEDIADLVTKVMEEPEENTAALGRLCKMVESK 169 >5E1J-A nrPDB Length = 741 Score = 31.7 bits (70), Expect = 1.6, Method: Composition-based stats. Identities = 13/127 (10%), Positives = 44/127 (34%), Gaps = 5/127 (3%) Query: 606 FSRIAYILPANESFGPLQISLGRTVKDIFKFMVIFIMVFVAFMIGMFNLYSYYIGAKQNE 665 + R+ + + + L + + ++++ + + ++ + + Sbjct: 189 YVRVIIFILSIRELRDTLVLLSGMLGTYLNILALWMLFLL-----FASWIAFVMFEDTQQ 243 Query: 666 AFTTVEESFKTLFWAIFGLSEVKSVVINYNHKFIENIGYVLYGVYNVTMVIVLLNMLIAM 725 T TL+ + + + V + +Y + V + N+++A+ Sbjct: 244 GLTVFTSYGATLYQMFILFTTSNNPDVWIPAYKSSRWSSVFFVLYVLIGVYFVTNLILAV 303 Query: 726 INSSFQE 732 + SF+E Sbjct: 304 VYDSFKE 310 >6GCS-2 nrPDB Length = 469 Score = 31.3 bits (69), Expect = 1.9, Method: Composition-based stats. Identities = 22/154 (14%), Positives = 55/154 (35%), Gaps = 18/154 (11%) Query: 596 GLYAIAVVLSFSRIAYILPA-NESFGP--LQISLGRTVKDIFKFMVIFIMVFVAFMIGMF 652 + +A+ + Y + N + P L + D ++ +V +F IG+ Sbjct: 317 SISHLAIFMIIIFSIYYINYINNQYNPIIYVNQLKGLIHDNAYLVLSMAIVVFSF-IGIP 375 Query: 653 NLYSYY-----IGAKQNEAF---------TTVEESFKTLFWAIFGLSEVKSVVINYNHKF 698 L ++ + + N + ++ + L+ + + +++IN N Sbjct: 376 PLLGFFGKLNILMSILNNGYYFISIVLIVASLISALYYLYLLNVSIQDKNNILINSNETV 435 Query: 699 IENIGYVLYGVYNVTMVIVLLNMLIAMINSSFQE 732 + Y+L + + + N LI I + + Sbjct: 436 SSVLSYILSSLIILITFGFIYNSLIIDIFNVYFN 469 >6CMO-R nrPDB Length = 463 Score = 31.3 bits (69), Expect = 1.9, Method: Composition-based stats. Identities = 9/79 (11%), Positives = 34/79 (43%), Gaps = 1/79 (1%) Query: 600 IAVVLSFSRIAYILPANESFGPLQISLGRTVKDIFKFMVIFIMVFVAFMIGMFNLYSYYI 659 I + + ++ + + + + + K++ + ++I+++ F+ + ++ ++YI Sbjct: 357 IIIFFCYGQLVFTVKEAAAQQQESATTQKAEKEVTRMVIIYVIAFLICWVPYASV-AFYI 415 Query: 660 GAKQNEAFTTVEESFKTLF 678 Q F + + F Sbjct: 416 FTHQGSCFGPIFMTIPAFF 434 >5W0P-A nrPDB Length = 906 Score = 31.3 bits (69), Expect = 1.9, Method: Composition-based stats. Identities = 9/79 (11%), Positives = 34/79 (43%), Gaps = 1/79 (1%) Query: 600 IAVVLSFSRIAYILPANESFGPLQISLGRTVKDIFKFMVIFIMVFVAFMIGMFNLYSYYI 659 I + + ++ + + + + + K++ + ++I+++ F+ + ++ ++YI Sbjct: 377 IIIFFCYGQLVFTVKEAAAQQQESATTQKAEKEVTRMVIIYVIAFLICWVPYASV-AFYI 435 Query: 660 GAKQNEAFTTVEESFKTLF 678 Q F + + F Sbjct: 436 FTHQGSCFGPIFMTIPAFF 454 >4RM9-A nrPDB Length = 587 Score = 31.3 bits (69), Expect = 1.9, Method: Composition-based stats. Identities = 26/149 (17%), Positives = 58/149 (38%), Gaps = 8/149 (5%) Query: 782 WMCELIQGQKQGFQEDAEMNKRNEEKKFGISGSHEDLSKFSLDKNQLAHNKQSSTRSSED 841 + I+ ++ + F ++K L H R + Sbjct: 241 FPWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILQLCMGNHELYMRRRKPDT 300 Query: 842 YHLNSFSNPPRQYQKIMKRLIKRYVLQAQIDKESDEVNEGELKEIKQDISSLRYELLEEK 901 + R+ +K K+L ++ + + +E+ E + ++ K+++ LR + EEK Sbjct: 301 IEVQQMKAQARE-EKHQKQLERQQLETEKKRRETVEREKEQMMREKEELM-LRLQDYEEK 358 Query: 902 SQNTEDLAELIRKLGERLSLEPKLEESRR 930 ++ E R+L E++ +LEE R+ Sbjct: 359 TKKAE------RELSEQIQRALQLEEERK 381 >4XD0-A nrPDB Length = 417 Score = 31.3 bits (69), Expect = 2.0, Method: Composition-based stats. Identities = 11/61 (18%), Positives = 29/61 (47%), Gaps = 2/61 (3%) Query: 99 ERFLDAAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLAVANEHLEITELLLKKENLS 158 + L A E + + K+L+ + L +++G + + +A + ++++ E L+ K Sbjct: 293 DEILTACEDKSPEFISKLLKTENIL--FEKNHLGWSPIIIAAYHGNMDVIEWLVSKGVNI 350 Query: 159 R 159 Sbjct: 351 N 351 >5FQM-A nrPDB Length = 269 Score = 31.3 bits (69), Expect = 2.3, Method: Composition-based stats. Identities = 12/78 (15%), Positives = 31/78 (39%), Gaps = 7/78 (8%) Query: 258 SQKQKHDSFSHSRSRINAYKGLA-----SPAYLSLSSED--PVMTALELSNELAVLANIE 310 Q + + R G+A + ++ ++ P+ + + AVLA ++ Sbjct: 1 MAAQLSEQLAELEKRSGGRLGVAVLDTATGRRIAYRGDERFPMCSTFKALLAAAVLARVD 60 Query: 311 KEFKNDYRKLSMQCKDFV 328 + + R+++ +D V Sbjct: 61 QGKERLDRRITYGKEDLV 78 >4EDG-A nrPDB Length = 329 Score = 30.5 bits (67), Expect = 3.8, Method: Composition-based stats. Identities = 29/143 (20%), Positives = 55/143 (38%), Gaps = 5/143 (3%) Query: 782 WMCELIQGQKQGFQEDAEMNK-RNEEKKFGISGSHEDLSKFSLDKNQLAHNKQS--STRS 838 + + +Q + + E E+ F + F L Q S + Sbjct: 60 FCHDFLQKKGYDIELAYEAGLLSRNEENFSYYDRFRNRIMFPLKNAQGRIVGYSGRTYTG 119 Query: 839 SEDYHLNSFSNPPRQYQKIMKRLIKRYVLQAQIDKESDEVNEGELKEIKQDISSLRYELL 898 E +LNS P Q +K++ L K ++ + + EG + IK D + L+ + Sbjct: 120 QEPKYLNSPETPIFQKRKLLYNLDK--ARKSIRKLDEIVLLEGFMDVIKSDTAGLKNVVA 177 Query: 899 EEKSQNTEDLAELIRKLGERLSL 921 +Q +++ IRKL ++L Sbjct: 178 TMGTQLSDEHITFIRKLTSNITL 200 >4C6Y-A nrPDB Length = 262 Score = 30.1 bits (66), Expect = 4.2, Method: Composition-based stats. Identities = 9/51 (17%), Positives = 24/51 (47%), Gaps = 2/51 (3%) Query: 280 ASPAYLSLSSED--PVMTALELSNELAVLANIEKEFKNDYRKLSMQCKDFV 328 A+ ++ ++ P+ + + AVLA +++ + R+++ D V Sbjct: 27 ATGRRIAYRGDERFPMCSTFKALLAAAVLAQVDQGKERLDRRITYSKADLV 77 >5FQI-A nrPDB Length = 269 Score = 30.1 bits (66), Expect = 4.3, Method: Composition-based stats. Identities = 14/68 (20%), Positives = 27/68 (39%), Gaps = 7/68 (10%) Query: 292 PVMTALELSNELAVLANIEKEFKNDYRKLSMQCKDFV-------VGLLDLCRNTEEVEAI 344 P+ + + AVLA +++ +N R+++ +D V + D E EA Sbjct: 42 PMCSTFKALLAAAVLARVDQGKENLDRRITYGKEDLVDYSPVTEKHVGDGMTVAELCEAA 101 Query: 345 LNGDAETR 352 + T Sbjct: 102 ITYSDNTA 109 >1G0D-A nrPDB Length = 695 Score = 30.1 bits (66), Expect = 4.4, Method: Composition-based stats. Identities = 15/67 (22%), Positives = 24/67 (35%), Gaps = 2/67 (2%) Query: 57 RGNENRLTHRRQTILREKGRRLANRGPAYMFNDHSTSLSIEEERFLDAAEYGNIPVVRKM 116 R +EN L HR + I RE R + RG + + + G V Sbjct: 14 RSHENNLAHRTREIDRE--RLIVRRGQPFSITLQCSDSLPPKHHLELVLHLGKRDEVVIK 71 Query: 117 LEECHSL 123 +++ H Sbjct: 72 VQKEHGA 78 >6NQ0-A nrPDB Length = 756 Score = 30.1 bits (66), Expect = 4.5, Method: Composition-based stats. Identities = 28/237 (11%), Positives = 80/237 (33%), Gaps = 43/237 (18%) Query: 531 GMLAIFAASFIARFMAFWHASKAQSIIDANDTLKDLTKVTLGDNVKYYNLA--RIKWDPT 588 + +F ++ + A + + + D + ++ LA R+ Sbjct: 475 ILNCVFIVYYLLEMLLKVFALGLRGYLSYPSNVFDGLLTVVLLVLEISTLAVYRLPHPGW 534 Query: 589 DPQIIS-----EGLYAIAVVLSFSRIAYILPANESFGPLQISLGRTVKDIFKFMVIFIMV 643 P+++ + + +++ F R I+P+ + + ++ V+++ F I ++V Sbjct: 535 RPEMVGLLSLWDMTRMLNMLIVF-RFLRIIPSMKPMAVVASTVLGLVQNMRAFGGILVVV 593 Query: 644 FVAFMI----------------------------GMFNLYSYYIGAKQNEAFTTVEESFK 675 + F I G F Y+ F + Sbjct: 594 YYVFAIIGINLFRGVIVALPGNSSLAPANGSAPCGSFEQLEYW-----ANNFDDFAAALV 648 Query: 676 TLFWAIFGLSEVKSVVINYNHKFIENIGYVLYGVYNVTMVIVLLNMLIAMINSSFQE 732 TL+ + V ++ ++ + + ++ + ++ +N+ +A+I +F Sbjct: 649 TLWNLMV--VNNWQVFLDAYRRYSGPWSKIYFVLWWLVSSVIWVNLFLALILENFLH 703 >6GCS-4 nrPDB Length = 486 Score = 30.1 bits (66), Expect = 5.1, Method: Composition-based stats. Identities = 18/118 (15%), Positives = 44/118 (37%), Gaps = 5/118 (4%) Query: 611 YILPANESFG-PLQISLGRTVK-DIFKFMVIFIMVFVAFMIGMFNLYSYYIGAKQNEAFT 668 Y + N + L +++G + + + I + + + + + I + Sbjct: 105 YNINFNSNLYYTLVLAIGLVILLNFWALDYISFYILFEATLPLLFILIH-IYGSSDSERA 163 Query: 669 TVEESFKTLFWAIFGLSEVKSVVINYNHKFIENIGYVLYGVYNVTMVIVLLNMLIAMI 726 + TL ++F L + + I N I + L+ + I+ L + IA++ Sbjct: 164 SFYVLMFTLSGSLFMLLSIVVISIVLN--TTNFINHNLFVLSLDLQTIIWLGLFIAIM 219 >4S1L-A nrPDB Length = 237 Score = 29.8 bits (65), Expect = 5.3, Method: Composition-based stats. Identities = 12/36 (33%), Positives = 18/36 (50%) Query: 361 NLSRLKLAIKYEVKKFVAHPNCQQQLLSIWYENLSG 396 +L R++ Y+ KFV P+C + WY L G Sbjct: 134 SLDRIRPPCSYKRNKFVDLPSCGGRCEKAWYVELDG 169 >4F61-I nrPDB Length = 240 Score = 29.4 bits (64), Expect = 7.6, Method: Composition-based stats. Identities = 30/163 (18%), Positives = 62/163 (38%), Gaps = 15/163 (9%) Query: 760 PVPFNLVPSPKSLLYLLLKFKKWMCELIQGQKQGFQEDAEMNKRNEEKKFGISGSHEDLS 819 P F+ VP L + + E IQ + + +E + + K HE Sbjct: 23 PPSFDGVPE---FNASLPRRRDPSLEEIQKKLEAAEERRKYQEAELLKHLAEKREHEREV 79 Query: 820 KFSLDKNQLAHNKQSSTRSSEDYHLNSFSNPPRQYQKIMKRLIKRYVLQAQIDKESDEVN 879 + K + + ++ N + + +++RL + DK ++EV Sbjct: 80 IQRAIEENNNWIKMAKEKLAQKMESNKENREAH-FAAMLERL-------QEKDKHAEEVR 131 Query: 880 EGELKEIKQDISSLRYELLEEKSQNTEDL----AELIRKLGER 918 + ++E I + +L ++ N E+ AEL++ L E+ Sbjct: 132 QRAIEENNNWIKMAKEKLAQKMESNKENRKYQEAELLKHLAEK 174 >4GX0-A nrPDB Length = 565 Score = 29.4 bits (64), Expect = 8.6, Method: Composition-based stats. Identities = 10/95 (10%), Positives = 38/95 (40%), Gaps = 8/95 (8%) Query: 634 FKFMVIFIMVFVAFMIGMFNLYSYYIGAKQNEAFTTVEESFKTLFWAIFGLSEVKSVVIN 693 K ++++ + ++ +++ Y + + A++ + +W I ++ + I Sbjct: 17 LKVLLLYCAFLLVMLLAYASIFRYLMWHLEGRAYSFMAGI----YWTITVMTTLGFGDIT 72 Query: 694 YNHKFIENIGYVLYGVYNVTMVIVL----LNMLIA 724 + ++ + + I+L ++M +A Sbjct: 73 FESDAGYLFASIVTVSGVIFLDIILPFGFVSMFLA 107 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.314 0.124 0.328 Lambda K H 0.267 0.0382 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 32,116,846 Number of Sequences: 36641 Number of extensions: 1239072 Number of successful extensions: 4468 Number of sequences better than 10.0: 119 Number of HSP's better than 10.0 without gapping: 113 Number of HSP's successfully gapped in prelim test: 63 Number of HSP's that attempted gapping in prelim test: 3688 Number of HSP's gapped (non-prelim): 387 length of query: 930 length of database: 10,336,785 effective HSP length: 106 effective length of query: 824 effective length of database: 6,452,839 effective search space: 5317139336 effective search space used: 5317139336 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 64 (29.4 bits)