BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q60177 (261 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 3H4P-A nrPDB 522 e-149 6HE5-A nrPDB 304 3e-83 2KU2-A nrPDB 228 3e-60 6J30-C nrPDB 199 1e-51 5FMG-E nrPDB 196 6e-51 5FMG-C nrPDB 192 1e-49 5LEZ-C nrPDB 189 7e-49 1G0U-D nrPDB 188 2e-48 2Z5C-C nrPDB 187 6e-48 5FMG-D nrPDB 184 4e-47 5GJR-F nrPDB 182 1e-46 4YA5-C nrPDB 182 2e-46 5LE5-B nrPDB 178 2e-45 5LF0-A nrPDB 171 4e-43 1IRU-A nrPDB 166 1e-41 5FMG-B nrPDB 165 2e-41 5FGG-F nrPDB 161 2e-40 6FVW-g nrPDB 160 4e-40 4FZC-A nrPDB 158 2e-39 6EPD-G nrPDB 150 7e-37 5FMG-F nrPDB 137 5e-33 5FMG-A nrPDB 129 9e-31 5FMG-G nrPDB 127 6e-30 5T0I-L nrPDB 126 8e-30 3NZW-E nrPDB 124 6e-29 5L5W-G nrPDB 115 3e-26 3IPM-H nrPDB 114 5e-26 6HEC-1 nrPDB 102 2e-22 3H4P-a nrPDB 100 6e-22 3UNH-H nrPDB 90 8e-19 5FMG-I nrPDB 81 4e-16 6AVO-B nrPDB 79 2e-15 6HV7-H nrPDB 72 2e-13 5FGI-H nrPDB 72 3e-13 3UNF-K nrPDB 70 9e-13 5FMG-L nrPDB 69 2e-12 6AVO-C nrPDB 66 2e-11 6EPF-2 nrPDB 66 2e-11 5L5A-K nrPDB 65 2e-11 6EPF-5 nrPDB 65 2e-11 5L4G-8 nrPDB 64 5e-11 5FMG-M nrPDB 63 1e-10 5LN3-5 nrPDB 63 2e-10 6HUB-H nrPDB 60 8e-10 6EPC-1 nrPDB 60 9e-10 3UNB-K nrPDB 60 1e-09 5L64-K nrPDB 60 1e-09 3NZW-L nrPDB 60 1e-09 5FGE-J nrPDB 56 2e-08 3NZW-K nrPDB 56 2e-08 3WXR-K nrPDB 55 2e-08 5MPC-h nrPDB 54 5e-08 5GJQ-a nrPDB 54 6e-08 5CZ8-K nrPDB 53 2e-07 5LEZ-N nrPDB 50 1e-06 5FMG-K nrPDB 49 3e-06 1Q5Q-H nrPDB 48 5e-06 1Q5R-H nrPDB 47 6e-06 5LF3-J nrPDB 45 4e-05 5LF6-M nrPDB 44 8e-05 5FMG-N nrPDB 44 9e-05 6EPE-7 nrPDB 44 9e-05 5GJQ-g nrPDB 44 9e-05 5FMG-J nrPDB 41 5e-04 2JAY-A nrPDB 41 5e-04 3UNF-N nrPDB 41 5e-04 4Y8P-I nrPDB 40 7e-04 3UNE-I nrPDB 40 0.001 6AVO-A nrPDB 39 0.002 5LZP-A nrPDB 37 0.006 5FMG-H nrPDB 37 0.007 6A94-A nrPDB 32 0.40 6DTT-A nrPDB 31 0.42 3JB9-S nrPDB 30 1.4 4HO7-A nrPDB 29 1.7 5HH9-A nrPDB 29 1.9 1HBX-G nrPDB 29 2.6 2GHB-A nrPDB 28 2.7 3IEF-A nrPDB 28 2.9 5K8K-A nrPDB 28 3.8 4NLE-A nrPDB 28 4.7 3MOP-A nrPDB 28 5.6 1BC8-C nrPDB 27 6.2 6A4U-A nrPDB 27 7.0 3M1C-A nrPDB 27 9.6 >3H4P-A nrPDB Length = 264 Score = 522 bits (1344), Expect = e-149, Method: Compositional matrix adjust. Identities = 261/261 (100%), Positives = 261/261 (100%) Query: 1 MQMVPPSAYDRAITVFSPEGRLYQVEYAREAVRRGTTAIGIACKDGVVLAVDRRITSKLV 60 MQMVPPSAYDRAITVFSPEGRLYQVEYAREAVRRGTTAIGIACKDGVVLAVDRRITSKLV Sbjct: 4 MQMVPPSAYDRAITVFSPEGRLYQVEYAREAVRRGTTAIGIACKDGVVLAVDRRITSKLV 63 Query: 61 KIRSIEKIFQIDDHVAAATSGLVADARVLIDRARLEAQIYRLTYGEEISIEMLAKKICDI 120 KIRSIEKIFQIDDHVAAATSGLVADARVLIDRARLEAQIYRLTYGEEISIEMLAKKICDI Sbjct: 64 KIRSIEKIFQIDDHVAAATSGLVADARVLIDRARLEAQIYRLTYGEEISIEMLAKKICDI 123 Query: 121 KQAYTQHGGVRPFGVSLLIAGIDKNEARLFETDPSGALIEYKATAIGSGRPVVMELLEKE 180 KQAYTQHGGVRPFGVSLLIAGIDKNEARLFETDPSGALIEYKATAIGSGRPVVMELLEKE Sbjct: 124 KQAYTQHGGVRPFGVSLLIAGIDKNEARLFETDPSGALIEYKATAIGSGRPVVMELLEKE 183 Query: 181 YRDDITLDEGLELAITALTKANEDIKPENVDVCIITVKDAQFKKIPVEEIKKLIEKVKKK 240 YRDDITLDEGLELAITALTKANEDIKPENVDVCIITVKDAQFKKIPVEEIKKLIEKVKKK Sbjct: 184 YRDDITLDEGLELAITALTKANEDIKPENVDVCIITVKDAQFKKIPVEEIKKLIEKVKKK 243 Query: 241 LNEENKKEEENREETKEKQEE 261 LNEENKKEEENREETKEKQEE Sbjct: 244 LNEENKKEEENREETKEKQEE 264 >6HE5-A nrPDB Length = 247 Score = 304 bits (778), Expect = 3e-83, Method: Compositional matrix adjust. Identities = 150/248 (60%), Positives = 195/248 (78%), Gaps = 2/248 (0%) Query: 1 MQMVPPSAYDRAITVFSPEGRLYQVEYAREAVRRGTTAIGIACKDGVVLAVDRRITSKLV 60 M +P YDRAITVFSP+GRL+QVEYAREAV+RG TAIGI CK+GV+L D+R+ SKL+ Sbjct: 1 MGHLPQMGYDRAITVFSPDGRLFQVEYAREAVKRGATAIGIKCKEGVILIADKRVGSKLL 60 Query: 61 KIRSIEKIFQIDDHVAAATSGLVADARVLIDRARLEAQIYRLTYGEEISIEMLAKKICDI 120 + +IEKI++ID+H+ AATSGLVADARVLIDRAR+EAQI RLTY E I+++ LAKKICD Sbjct: 61 EADTIEKIYKIDEHICAATSGLVADARVLIDRARIEAQINRLTYDEPITVKELAKKICDF 120 Query: 121 KQAYTQHGGVRPFGVSLLIAGIDKNEARLFETDPSGALIEYKATAIGSGRPVVMELLEKE 180 KQ YTQ+GGVRPFGVSLLIAG+D+ +L+ETDPSGAL+EYKATAIG GR V E EKE Sbjct: 121 KQQYTQYGGVRPFGVSLLIAGVDEV-PKLYETDPSGALLEYKATAIGMGRNAVTEFFEKE 179 Query: 181 YRDDITLDEGLELAITALTKANE-DIKPENVDVCIITVKDAQFKKIPVEEIKKLIEKVKK 239 YRDD++ D+ + L + A+ + E ++ PEN++V + V D FK++ EE+K +E+ + Sbjct: 180 YRDDLSFDDAMVLGLVAMGLSIESELVPENIEVGYVKVDDRTFKEVSPEELKPYVERANE 239 Query: 240 KLNEENKK 247 ++ E KK Sbjct: 240 RIRELLKK 247 >2KU2-A nrPDB Length = 237 Score = 228 bits (580), Expect = 3e-60, Method: Compositional matrix adjust. Identities = 120/231 (51%), Positives = 169/231 (73%), Gaps = 8/231 (3%) Query: 8 AYDRAITVFSPEGRLYQVEYAREAVRRGTTAIGIACKDGVVLAVDRRITSKLVKIRSIEK 67 A RAITVFSP+GRL+QVEYAREAV++G+TA+G+ +GV+L D+++ S+L++ SIEK Sbjct: 11 AGGRAITVFSPDGRLFQVEYAREAVKKGSTALGMKFANGVLLISDKKVRSRLIEQNSIEK 70 Query: 68 IFQIDDHVAAATSGLVADARVLIDRARLEAQIYRLTYGEEISIEMLAKKICDIKQAYTQH 127 I IDD+VAA TSGLVADARVL+D AR+ AQ ++TYG ++IE L K++ D Q YTQ+ Sbjct: 71 IQLIDDYVAAVTSGLVADARVLVDFARISAQQEKVTYGSLVNIENLVKRVADQMQQYTQY 130 Query: 128 GGVRPFGVSLLIAGIDKNEARLFETDPSGALIEYKATAIGSGRPVVMELLEKEYRDDITL 187 GGVRP+GVSL+ AGID+ RLF+ DP+G + EYKATAIGSG+ V+ LE+EY++++ Sbjct: 131 GGVRPYGVSLIFAGIDQIGPRLFDCDPAGTINEYKATAIGSGKDAVVSFLEREYKENLPE 190 Query: 188 DEGLELAITALTKA---NEDIK-PENVDVCIITVKDAQFKKIPVEEIKKLI 234 E + L I AL + E++K PE + ITV + +++ EE+KK + Sbjct: 191 KEAVTLGIKALKSSLEEGEELKAPE---IASITVGN-KYRIYDQEEVKKFL 237 >6J30-C nrPDB Length = 258 Score = 199 bits (505), Expect = 1e-51, Method: Compositional matrix adjust. Identities = 92/197 (46%), Positives = 137/197 (69%), Gaps = 2/197 (1%) Query: 9 YDRAITVFSPEGRLYQVEYAREAVRRGTTAIGIACKDGVVLAVDRRITSKLV-KIRSIEK 67 YD T+FSPEGRLYQVEYA E++ TAIGI DG+VLA +R++TS L+ + S EK Sbjct: 6 YDSRTTIFSPEGRLYQVEYALESISHAGTAIGIMASDGIVLAAERKVTSTLLEQDTSTEK 65 Query: 68 IFQIDDHVAAATSGLVADARVLIDRARLEAQIYRLTYGEEISIEMLAKKICDIKQAYTQH 127 +++++D +A A +GL ADA +LI+ AR+ AQ Y TY E+I +E+L +++ DIKQ YTQH Sbjct: 66 LYKLNDKIAVAVAGLTADAEILINTARIHAQNYLKTYNEDIPVEILVRRLSDIKQGYTQH 125 Query: 128 GGVRPFGVSLLIAGIDKNEA-RLFETDPSGALIEYKATAIGSGRPVVMELLEKEYRDDIT 186 GG+RPFGVS + AG D +L+ ++PSG +KA ++G+ LL+ +Y+DD+ Sbjct: 126 GGLRPFGVSFIYAGYDDRYGYQLYTSNPSGNYTGWKAISVGANTSAAQTLLQMDYKDDMK 185 Query: 187 LDEGLELAITALTKANE 203 +D+ +ELA+ L+K + Sbjct: 186 VDDAIELALKTLSKTTD 202 >5FMG-E nrPDB Length = 256 Score = 196 bits (499), Expect = 6e-51, Method: Compositional matrix adjust. Identities = 100/237 (42%), Positives = 147/237 (62%), Gaps = 8/237 (3%) Query: 7 SAYDRAITVFSPEGRLYQVEYAREAVRRGTTAIGIACKDGVVLAVDRRITSKLVKIRSIE 66 S YDR + FSPEGRL+QVEYA A++ G+TA+GI DGV+LA +RRI+S L++ S+E Sbjct: 6 SEYDRGVNTFSPEGRLFQVEYALGAIKLGSTAVGICVNDGVILASERRISSTLIEKDSVE 65 Query: 67 KIFQIDDHVAAATSGLVADARVLIDRARLEAQIYRLTYGEEISIEMLAKKICDIKQAYTQ 126 K+ IDDH+ A SGL+ADAR LID AR+E Y+ Y E I+I+ + I ++ ++ Sbjct: 66 KLLSIDDHIGCAMSGLMADARTLIDYARVECNHYKFIYNENINIKSCVELISELALDFSN 125 Query: 127 HGG-------VRPFGVSLLIAGIDKNEARLFETDPSGALIEYKATAIGSGRPVVMELLEK 179 RPFGV+LLI G+DKN L+ T+PSG + A +IGS + LL++ Sbjct: 126 LSDSKRKKIMSRPFGVALLIGGVDKNGPCLWYTEPSGTNTRFSAASIGSAQEGAELLLQE 185 Query: 180 EYRDDITLDEGLELAITALTKANED-IKPENVDVCIITVKDAQFKKIPVEEIKKLIE 235 Y+ D+T ++ LA+T L + ED + NV++C I D F K ++I ++I+ Sbjct: 186 NYKKDMTFEQAEILALTVLRQVMEDKLSTSNVEICAIKKSDQTFYKYNTDDISRIID 242 >5FMG-C nrPDB Length = 246 Score = 192 bits (488), Expect = 1e-49, Method: Compositional matrix adjust. Identities = 109/242 (45%), Positives = 157/242 (64%), Gaps = 6/242 (2%) Query: 9 YDRAITVFSPEGRLYQVEYAREAVRRGTTAIGIACKDGVVLAVDRRITSKLV-KIRSIEK 67 YD T FSPEGRLYQVEYA EA+ + IG+ KDGV+L D+ SKL+ K + EK Sbjct: 5 YDSRTTTFSPEGRLYQVEYALEAINNASITIGLITKDGVILGADKVFISKLIDKANNYEK 64 Query: 68 IFQIDDHVAAATSGLVADARVLIDRARLEAQIYRLTYGEEISIEMLAKKICDIKQAYTQH 127 I++ID H+ +GL ADA +LI+++RL AQ Y Y E + L +ICDIKQ+YTQ+ Sbjct: 65 IYKIDKHIFCGVAGLNADANILINQSRLYAQRYLYNYNEVQPVSQLVVQICDIKQSYTQY 124 Query: 128 GGVRPFGVSLLIAGID-KNEARLFETDPSGALIEYKATAIGSGRPVVMELLEKEYRDDIT 186 GG+RP+GVS LI G D K+ +L+ TDPSG + ATAIG+ +L++E+++D+T Sbjct: 125 GGLRPYGVSFLIGGYDTKDGYQLYHTDPSGNYSGWFATAIGTNNLTASSVLKQEWKNDMT 184 Query: 187 LDEGLELAITALTKA--NEDIKPENVDVCIITVKDAQ-FKKIPVE-EIKKLIEKVKKKLN 242 L+EGL LA+ L K+ E K E +++ +T KD + ++K E EI++LI+ +K Sbjct: 185 LEEGLLLALKTLAKSTDTEIPKSEKIELAYLTNKDGEVYQKYLTEKEIEELIKLYTQKYI 244 Query: 243 EE 244 +E Sbjct: 245 KE 246 >5LEZ-C nrPDB Length = 248 Score = 189 bits (481), Expect = 7e-49, Method: Compositional matrix adjust. Identities = 103/230 (44%), Positives = 153/230 (66%), Gaps = 5/230 (2%) Query: 8 AYDRAITVFSPEGRLYQVEYAREAVRRGTTAIGIACKDGVVLAVDRRITSKLVKIRSIEK 67 +YDRAITVFSP+G L+QVEYA+EAV++G+TA+G+ +D VVL V+++ +KL R++ K Sbjct: 2 SYDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGRDIVVLGVEKKSVAKLQDERTVRK 61 Query: 68 IFQIDDHVAAATSGLVADARVLIDRARLEAQIYRLTYGEEISIEMLAKKICDIKQAYTQH 127 I +DD+V A +GL ADAR++I+RAR+E Q +RLT + +++E + + I +KQ YTQ Sbjct: 62 ICALDDNVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQS 121 Query: 128 GGVRPFGVSLLIAGID-KNEARLFETDPSGALIEYKATAIGSGRPVVMELLEKEYRDDI- 185 G RPFG+S LI G D RL++TDPSG +KA AIG G V E LEK Y D+ Sbjct: 122 NGRRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKNYTDEAI 181 Query: 186 -TLDEGLELAITALTKANEDIKPENVDVCIITVKDAQFKKIPVEEIKKLI 234 T D ++L I AL + + +N+++ ++ +D K + EEI+K + Sbjct: 182 ETDDLTIKLVIKALLEVVQS-GGKNIELAVMR-RDQSLKILNPEEIEKYV 229 >1G0U-D nrPDB Length = 241 Score = 188 bits (478), Expect = 2e-48, Method: Compositional matrix adjust. Identities = 105/236 (44%), Positives = 147/236 (62%), Gaps = 6/236 (2%) Query: 7 SAYDRAITVFSPEGRLYQVEYAREAVRRGTTAIGIACKDGVVLAVDRRITSKLVKIRSIE 66 S YDR ++ FSPEGRL+QVEY+ EA++ G+TAIGIA K+GVVL V++R TS L++ SIE Sbjct: 6 SEYDRGVSTFSPEGRLFQVEYSLEAIKLGSTAIGIATKEGVVLGVEKRATSPLLESDSIE 65 Query: 67 KIFQIDDHVAAATSGLVADARVLIDRARLEAQIYRLTYGEEISIEMLAKKICDIKQAYTQ 126 KI +ID H+ A SGL ADAR +I+ AR A + L Y E+I++E L + +CD+ A Sbjct: 66 KIVEIDRHIGCAMSGLTADARSMIEHARTAAVTHNLYYDEDINVESLTQSVCDLAAAAAM 125 Query: 127 HGGVRPFGVSLLIAGIDKNEA-RLFETDPSGALIEYKATAIGSGRPVVMELLEKEYRDDI 185 RPFGV+LLIAG D ++ +LF +PSG Y A AIGSG L E+ + Sbjct: 126 S---RPFGVALLIAGHDADDGYQLFHAEPSGTFYRYNAKAIGSGSEGAQAELLNEWHSSL 182 Query: 186 TLDEGLELAITALTKANED-IKPENVDVCIITVKDAQFKKIPVEEIKKLIEKVKKK 240 TL E L + L + E+ + N + IT +D FK E+ +LI+++K+K Sbjct: 183 TLKEAELLVLKILKQVMEEKLDENNAQLSCITKQDG-FKIYDNEKTAELIKELKEK 237 >2Z5C-C nrPDB Length = 262 Score = 187 bits (474), Expect = 6e-48, Method: Compositional matrix adjust. Identities = 106/250 (42%), Positives = 152/250 (60%), Gaps = 9/250 (3%) Query: 7 SAYDRAITVFSPEGRLYQVEYAREAVRRGTTAIGIACKDGVVLAVDRRITSKLVKIRSIE 66 S YDR ++ FSPEGRL+QVEY+ EA++ G+TAIGIA K+GVVL V++R TS L++ SIE Sbjct: 8 SEYDRGVSTFSPEGRLFQVEYSLEAIKLGSTAIGIATKEGVVLGVEKRATSPLLESDSIE 67 Query: 67 KIFQIDDHVAAATSGLVADARVLIDRARLEAQIYRLTYGEEISIEMLAKKICDIKQAYTQ 126 KI +ID H+ A SGL ADAR +I+ AR A + L Y E+I++E L + +CD+ + + Sbjct: 68 KIVEIDRHIGCAMSGLTADARSMIEHARTAAVTHNLYYDEDINVESLTQSVCDLALRFGE 127 Query: 127 HGG------VRPFGVSLLIAGIDKNEA-RLFETDPSGALIEYKATAIGSGRPVVMELLEK 179 RPFGV+LLIAG D ++ +LF +PSG Y A AIGSG L Sbjct: 128 GASGEERLMSRPFGVALLIAGHDADDGYQLFHAEPSGTFYRYNAKAIGSGSEGAQAELLN 187 Query: 180 EYRDDITLDEGLELAITALTKANED-IKPENVDVCIITVKDAQFKKIPVEEIKKLIEKVK 238 E+ +TL E L + L + E+ + N + IT +D FK E+ +LI+++K Sbjct: 188 EWHSSLTLKEAELLVLKILKQVMEEKLDENNAQLSCITKQDG-FKIYDNEKTAELIKELK 246 Query: 239 KKLNEENKKE 248 +K E+ +E Sbjct: 247 EKEAAESPEE 256 >5FMG-D nrPDB Length = 241 Score = 184 bits (466), Expect = 4e-47, Method: Compositional matrix adjust. Identities = 97/243 (39%), Positives = 155/243 (63%), Gaps = 4/243 (1%) Query: 8 AYDRAITVFSPEGRLYQVEYAREAVRRGTTAIGIACKDGVVLAVDRRITSKLVKIRSIEK 67 +YDRAITVFSP+G L QVE+A EAV++G A+ I + VLAV+++ KL ++ EK Sbjct: 2 SYDRAITVFSPDGHLLQVEHALEAVKKGGCAVAIKSSNFAVLAVEKKNIPKLQNPKTTEK 61 Query: 68 IFQIDDHVAAATSGLVADARVLIDRARLEAQIYRLTYGEEISIEMLAKKICDIKQAYTQH 127 + ++D+H A +GL ADARVL+++ RLE Q Y L E ++ +AK + ++Q +T Sbjct: 62 LIKLDEHNCLAFAGLNADARVLVNKTRLECQRYYLNMDEPAPVDYIAKYVAKVQQKFTHR 121 Query: 128 GGVRPFGVSLLIAGIDKN-EARLFETDPSGALIEYKATAIGSGRPVVMELLEKEYRDDIT 186 GGVRPFG++ LIAG N E +++T+PSG +KA AIG +V E LEK Y++++ Sbjct: 122 GGVRPFGIATLIAGFKNNKEICIYQTEPSGIYAAWKAQAIGKNAKIVQEFLEKNYQENME 181 Query: 187 LDEGLELAITALTKANEDIKPENVDVCIITVKDAQFKKIPVEEIKKLIEKVKKKLNEENK 246 + + LA+ A+ + E + +NV+V ++T KD F I +EI ++E + ++ + N+ Sbjct: 182 QKDCIFLALKAIFEVVE-LSSKNVEVALLTEKDLTF--IEEQEINSMVELIDQERTKNNE 238 Query: 247 KEE 249 + E Sbjct: 239 QNE 241 >5GJR-F nrPDB Length = 241 Score = 182 bits (462), Expect = 1e-46, Method: Compositional matrix adjust. Identities = 96/237 (40%), Positives = 149/237 (62%), Gaps = 7/237 (2%) Query: 7 SAYDRAITVFSPEGRLYQVEYAREAVRRGTTAIGIACKDGVVLAVDRRITSKLVKIRSIE 66 S YDR + FSPEGRL+QVEYA EA++ G+TAIGI +GV LAV++RITS L++ SIE Sbjct: 6 SEYDRGVNTFSPEGRLFQVEYAIEAIKLGSTAIGIQTSEGVCLAVEKRITSPLMEPSSIE 65 Query: 67 KIFQIDDHVAAATSGLVADARVLIDRARLEAQIYRLTYGEEISIEMLAKKICDIKQAYTQ 126 KI +ID H+ A SGL+ADA+ LID+AR+E Q + TY E +++E + + + ++ + + Sbjct: 66 KIVEIDAHIGCAMSGLIADAKTLIDKARVETQNHWFTYNETMTVESVTQAVSNLALQFGE 125 Query: 127 H----GGV-RPFGVSLLIAGIDKNEARLFETDPSGALIEYKATAIGSGRPVVMELLEKEY 181 G + RPFGV+LL G+D+ +LF DPSG ++ A AIGS L++ Y Sbjct: 126 EDADPGAMSRPFGVALLFGGVDEKGPQLFHMDPSGTFVQCDARAIGSASEGAQSSLQEVY 185 Query: 182 RDDITLDEGLELAITALTKANEDIKPENVDVCIITVKDAQ-FKKIPVEEIKKLIEKV 237 +TL E ++ ++ L + E+ K ++ + TV+ Q F EE++++I+ + Sbjct: 186 HKSMTLKEAIKSSLIILKQVMEE-KLNATNIELATVQPGQNFHMFTKEELEEVIKDI 241 >4YA5-C nrPDB Length = 254 Score = 182 bits (461), Expect = 2e-46, Method: Compositional matrix adjust. Identities = 97/237 (40%), Positives = 152/237 (64%), Gaps = 8/237 (3%) Query: 7 SAYDRAITVFSPEGRLYQVEYAREAVRRGTTAIGIACKDGVVLAVDRRITSKLVKIR-SI 65 S YDRA+++FSP+G ++QVEYA EAV+RGT A+G+ K+ VVL +RR T KL R + Sbjct: 2 SGYDRALSIFSPDGHIFQVEYALEAVKRGTCAVGVKGKNCVVLGCERRSTLKLQDTRITP 61 Query: 66 EKIFQIDDHVAAATSGLVADARVLIDRARLEAQIYRLTYGEEISIEMLAKKICDIKQAYT 125 K+ +ID HV + SGL AD+R+LI++AR+EAQ +RLT + +++E L + + ++Q YT Sbjct: 62 SKVSKIDSHVVLSFSGLNADSRILIEKARVEAQSHRLTLEDPVTVEYLTRYVAGVQQRYT 121 Query: 126 QHGGVRPFGVSLLIAGIDK--NEARLFETDPSGALIEYKATAIGSGRPVVMELLEKEY-- 181 Q GGVRPFGVS LIAG D +E +L++T+PSG + A IG V E LEK Y Sbjct: 122 QSGGVRPFGVSTLIAGFDPRDDEPKLYQTEPSGIYSSWSAQTIGRNSKTVREFLEKNYDR 181 Query: 182 -RDDITLDEGLELAITALTKANEDIKPENVDVCIITVKDAQFKKIPVEEIKKLIEKV 237 T++E ++L + +L + + +N+++ ++ D+ + EEI + + ++ Sbjct: 182 KEPPATVEECVKLTVRSLLEVVQ-TGAKNIEITVVK-PDSDIVALSSEEINQYVTQI 236 >5LE5-B nrPDB Length = 261 Score = 178 bits (452), Expect = 2e-45, Method: Compositional matrix adjust. Identities = 98/233 (42%), Positives = 148/233 (63%), Gaps = 7/233 (3%) Query: 9 YDRAITVFSPEGRLYQVEYAREAVRRGTTAIGIACKDGVVLAVDRRITSKLV-KIRSIEK 67 YD T+FSPEGRLYQVEYA EA+ T +GI DGV+LA +RR KL+ ++ EK Sbjct: 5 YDSRTTIFSPEGRLYQVEYAMEAIGHAGTCLGILANDGVLLAAERRNIHKLLDEVFFSEK 64 Query: 68 IFQIDDHVAAATSGLVADARVLIDRARLEAQIYRLTYGEEISIEMLAKKICDIKQAYTQH 127 I+++++ +A + +G+ +DA VL + RL AQ Y L Y E I E L +CDIKQAYTQ Sbjct: 65 IYKLNEDMACSVAGITSDANVLTNELRLIAQRYLLQYQEPIPCEQLVTALCDIKQAYTQF 124 Query: 128 GGVRPFGVSLLIAGIDKNEA-RLFETDPSGALIEYKATAIGSGRPVVMELLEKEYRD-DI 185 GG RPFGVSLL G DK+ +L+++DPSG +KAT IG+ + +L+++Y++ ++ Sbjct: 125 GGKRPFGVSLLYIGWDKHYGFQLYQSDPSGNYGGWKATCIGNNSAAAVSMLKQDYKEGEM 184 Query: 186 TLDEGLELAITALTKANE--DIKPENVDVCIITVKDAQ--FKKIPVEEIKKLI 234 TL L LAI L K + + E V++ +T ++ + + + +E+++LI Sbjct: 185 TLKSALALAIKVLNKTMDVSKLSAEKVEIATLTRENGKTVIRVLKQKEVEQLI 237 >5LF0-A nrPDB Length = 234 Score = 171 bits (432), Expect = 4e-43, Method: Compositional matrix adjust. Identities = 91/231 (39%), Positives = 134/231 (58%), Gaps = 3/231 (1%) Query: 8 AYDRAITVFSPEGRLYQVEYAREAVRRGTTAIGIACKDGVVLAVDRRITSKLVKIRSIEK 67 Y ++T FSP G+L Q+EYA AV G ++GI +GVVLA +++ S L RS+ K Sbjct: 5 GYSFSLTTFSPSGKLVQIEYALAAVAGGAPSVGIKAANGVVLATEKKQKSILYDERSVHK 64 Query: 68 IFQIDDHVAAATSGLVADARVLIDRARLEAQIYRLTYGEEISIEMLAKKICDIKQAYTQH 127 + I H+ SG+ D RVL+ RAR AQ Y L Y E I L +++ + Q YTQ Sbjct: 65 VEPITKHIGLVYSGMGPDYRVLVHRARKLAQQYYLVYQEPIPTAQLVQRVASVMQEYTQS 124 Query: 128 GGVRPFGVSLLIAGIDKNEARLFETDPSGALIEYKATAIGSGRPVVMELLEKEYRDDITL 187 GGVRPFGVSLLI G ++ LF++DPSGA +KATA+G LEK Y +D+ L Sbjct: 125 GGVRPFGVSLLICGWNEGRPYLFQSDPSGAYFAWKATAMGKNYVNGKTFLEKRYNEDLEL 184 Query: 188 DEGLELAITALTKANE-DIKPENVDVCIITVKDAQFKKIPVEEIKKLIEKV 237 ++ + AI L ++ E + +N++V I +A F+++ E+K + + Sbjct: 185 EDAIHTAILTLKESFEGQMTEDNIEVGI--CNEAGFRRLTPTEVKDYLAAI 233 >1IRU-A nrPDB Length = 246 Score = 166 bits (419), Expect = 1e-41, Method: Compositional matrix adjust. Identities = 84/229 (36%), Positives = 143/229 (62%), Gaps = 5/229 (2%) Query: 7 SAYDRAITVFSPEGRLYQVEYAREAVRRG-TTAIGIACKDGVVLAVDRRITSKLVKIRSI 65 + +DR IT+FSPEGRLYQVEYA +A+ +G T++ + KD V+ +++ KL+ ++ Sbjct: 7 AGFDRHITIFSPEGRLYQVEYAFKAINQGGLTSVAVRGKDCAVIVTQKKVPDKLLDSSTV 66 Query: 66 EKIFQIDDHVAAATSGLVADARVLIDRARLEAQIYRLTYGEEISIEMLAKKICDIKQAYT 125 +F+I +++ +G+ AD+R + RAR EA ++ YG EI ++ML K+I DI Q YT Sbjct: 67 THLFKITENIGCVMTGMTADSRSQVQRARYEAANWKYKYGYEIPVDMLCKRIADISQVYT 126 Query: 126 QHGGVRPFGVSLLIAGIDKNEA-RLFETDPSGALIEYKATAIGSGRPVVMELLEKEYRD- 183 Q+ +RP G +++ GID+ + ++++ DP+G +KATA G + LEK+ + Sbjct: 127 QNAEMRPLGCCMILIGIDEEQGPQVYKCDPAGYYCGFKATAAGVKQTESTSFLEKKVKKK 186 Query: 184 -DITLDEGLELAITAL-TKANEDIKPENVDVCIITVKDAQFKKIPVEEI 230 D T ++ +E AIT L T + D KP ++V ++TV++ +F+ + EI Sbjct: 187 FDWTFEQTVETAITCLSTVLSIDFKPSEIEVGVVTVENPKFRILTEAEI 235 >5FMG-B nrPDB Length = 235 Score = 165 bits (417), Expect = 2e-41, Method: Compositional matrix adjust. Identities = 89/224 (39%), Positives = 132/224 (58%), Gaps = 2/224 (0%) Query: 9 YDRAITVFSPEGRLYQVEYAREAVRRGTTAIGIACKDGVVLAVDRRITSKLVKIRSIEKI 68 Y ++T FSP G+L Q+EYA V + A+GI K+GV++A +++ ++L++ SI KI Sbjct: 6 YSFSLTTFSPTGKLVQIEYALNRVSSSSPALGIRAKNGVIIATEKKSPNELIEENSIFKI 65 Query: 69 FQIDDHVAAATSGLVADARVLIDRARLEAQIYRLTYGEEISIEMLAKKICDIKQAYTQHG 128 QI +H+ +G+ D RVL+ RAR EA Y L YG EI ++ L K I I Q +TQ G Sbjct: 66 QQISEHIGIVYAGMPGDFRVLLKRARKEAIRYSLQYGSEILVKELVKIIASIVQEFTQTG 125 Query: 129 GVRPFGVSLLIAGIDKNEARLFETDPSGALIEYKATAIGSGRPVVMELLEKEYRDDITLD 188 GVRPFG+SLLI G+D L++ DPSG + AT +G M LEK Y DI ++ Sbjct: 126 GVRPFGLSLLICGVDVYGYHLYQIDPSGCYFNWMATCVGKDYQNNMSFLEKRYNKDIEIE 185 Query: 189 EGLELAITALTKANEDIKPE-NVDVCIITVKDAQFKKIPVEEIK 231 + + AI L ++ E + E N+++ + + FK + EIK Sbjct: 186 DAIHTAILTLKESYEGVLNEKNIEIG-VAYDNKPFKILTQNEIK 228 >5FGG-F nrPDB Length = 288 Score = 161 bits (408), Expect = 2e-40, Method: Compositional matrix adjust. Identities = 90/243 (37%), Positives = 141/243 (58%), Gaps = 7/243 (2%) Query: 7 SAYDRAITVFSPEGRLYQVEYAREAVRRGTTAIGIACKDGVVLAVDRRITSKLVKIRSIE 66 + YD + +VFSP+GR +QVEYA +AV GTT+IGI C DGVV AV++ ITSKL+ + Sbjct: 6 TGYDLSNSVFSPDGRNFQVEYAVKAVENGTTSIGIKCNDGVVFAVEKLITSKLLVPQKNV 65 Query: 67 KIFQIDDHVAAATSGLVADARVLIDRARLEAQIYRLTYGEEISIEMLAKKICDIKQAYTQ 126 KI +D H+ SGL+ D R L++R R EA ++ Y I I A ++ QA+T Sbjct: 66 KIQVVDRHIGCVYSGLIPDGRHLVNRGREEAASFKKLYKTPIPIPAFADRLGQYVQAHTL 125 Query: 127 HGGVRPFGVSLLIAGIDKNEARLFETDPSGALIEYKATAIGSGRPVVMELLEK---EYRD 183 + VRPFGVS + G+DKN A L+ +PSG+ YK A G GR LEK + + Sbjct: 126 YNSVRPFGVSTIFGGVDKNGAHLYMLEPSGSYWGYKGAATGKGRQSAKAELEKLVDHHPE 185 Query: 184 DITLDEGLELAITALTKANEDIKPENVDV----CIITVKDAQFKKIPVEEIKKLIEKVKK 239 ++ E ++ A + A+ED K ++ ++ C ++ + K + + +++ I+ +K Sbjct: 186 GLSAREAVKQAAKIIYLAHEDNKEKDFELEISWCSLSETNGLHKFVKGDLLQEAIDFAQK 245 Query: 240 KLN 242 ++N Sbjct: 246 EIN 248 >6FVW-g nrPDB Length = 245 Score = 160 bits (406), Expect = 4e-40, Method: Compositional matrix adjust. Identities = 90/243 (37%), Positives = 141/243 (58%), Gaps = 7/243 (2%) Query: 7 SAYDRAITVFSPEGRLYQVEYAREAVRRGTTAIGIACKDGVVLAVDRRITSKLVKIRSIE 66 + YD + +VFSP+GR +QVEYA +AV GTT+IGI C DGVV AV++ ITSKL+ + Sbjct: 3 TGYDLSNSVFSPDGRNFQVEYAVKAVENGTTSIGIKCNDGVVFAVEKLITSKLLVPQKNV 62 Query: 67 KIFQIDDHVAAATSGLVADARVLIDRARLEAQIYRLTYGEEISIEMLAKKICDIKQAYTQ 126 KI +D H+ SGL+ D R L++R R EA ++ Y I I A ++ QA+T Sbjct: 63 KIQVVDRHIGCVYSGLIPDGRHLVNRGREEAASFKKLYKTPIPIPAFADRLGQYVQAHTL 122 Query: 127 HGGVRPFGVSLLIAGIDKNEARLFETDPSGALIEYKATAIGSGRPVVMELLEK---EYRD 183 + VRPFGVS + G+DKN A L+ +PSG+ YK A G GR LEK + + Sbjct: 123 YNSVRPFGVSTIFGGVDKNGAHLYMLEPSGSYWGYKGAATGKGRQSAKAELEKLVDHHPE 182 Query: 184 DITLDEGLELAITALTKANEDIKPENVDV----CIITVKDAQFKKIPVEEIKKLIEKVKK 239 ++ E ++ A + A+ED K ++ ++ C ++ + K + + +++ I+ +K Sbjct: 183 GLSAREAVKQAAKIIYLAHEDNKEKDFELEISWCSLSETNGLHKFVKGDLLQEAIDFAQK 242 Query: 240 KLN 242 ++N Sbjct: 243 EIN 245 >4FZC-A nrPDB Length = 250 Score = 158 bits (399), Expect = 2e-39, Method: Compositional matrix adjust. Identities = 90/246 (36%), Positives = 141/246 (57%), Gaps = 17/246 (6%) Query: 9 YDRAITVFSPEGRLYQVEYAREAVRRGTTAIGIACKDGVVLAVDRRITSKLVKIRSIEKI 68 Y ++T FSP G+L Q++YA AV++G T++GI +GVV+A +++ +S L ++ K+ Sbjct: 5 YSFSLTTFSPSGKLGQIDYALTAVKQGVTSLGIKATNGVVIATEKKSSSPLAMSETLSKV 64 Query: 69 FQIDDHVAAATSGLVADARVLIDRARLEAQI-YRLTYGEEISIEMLAKKICDIKQAYTQH 127 + + A SG+ D RVL+D++R A Y+ YGE ++L ++ I Q TQ Sbjct: 65 SLLTPDIGAVYSGMGPDYRVLVDKSRKVAHTSYKRIYGEYPPTKLLVSEVAKIMQEATQS 124 Query: 128 GGVRPFGVSLLIAGIDK-NEARLFETDPSGALIEYKATAIGSGRPVVMELLEKEYRDDIT 186 GGVRPFGVSLLIAG D+ N L++ DPSG+ +KATAIG G LEK + D++ Sbjct: 125 GGVRPFGVSLLIAGHDEFNGFSLYQVDPSGSYFPWKATAIGKGSVAAKTFLEKRWNDELE 184 Query: 187 LDEGLELAITALTKANED-----------IKPENVDVC----IITVKDAQFKKIPVEEIK 231 L++ + +A+ L ++ E I EN D+ I T K +F+K+ +EI Sbjct: 185 LEDAIHIALLTLKESVEGEFNGDTIELAIIGDENPDLLGYTGIPTDKGPRFRKLTSQEIN 244 Query: 232 KLIEKV 237 +E + Sbjct: 245 DRLEAL 250 >6EPD-G nrPDB Length = 255 Score = 150 bits (378), Expect = 7e-37, Method: Compositional matrix adjust. Identities = 86/227 (37%), Positives = 125/227 (55%), Gaps = 23/227 (10%) Query: 7 SAYDRAITVFSPEGRLYQVEYAREAVRRGTTAIGIACKDGVVLAVDRRITSKLVKIRSIE 66 + YD + + FSP+GR++QVEYA +AV +TAIGI CKDGVV V++ + SKL + S + Sbjct: 6 TGYDLSASTFSPDGRVFQVEYAMKAVENSSTAIGIRCKDGVVFGVEKLVLSKLYEEGSNK 65 Query: 67 KIFQIDDHVAAATSGLVADARVLIDRARLEAQIYRLTYGEEISIEMLAKKICDIKQAYTQ 126 ++F +D HV A +GL+ADAR L D AR EA +R +G I ++ LA ++ AYT Sbjct: 66 RLFNVDRHVGMAVAGLLADARSLADIAREEASNFRSNFGYNIPLKHLADRVAMYVHAYTL 125 Query: 127 HGGVRPFGVSLLIAGIDKNE-ARLFETDPSGALIEYKATAIGSGRPVV------MELLEK 179 + VRPFG S ++ N+ A+L+ DPSG Y AIG R +++ E Sbjct: 126 YSAVRPFGCSFMLGSYSVNDGAQLYMIDPSGVSYGYWGCAIGKARQAAKTEIEKLQMKEM 185 Query: 180 EYRD-------------DITLDEGLELAITA---LTKANEDIKPENV 210 RD D D+ EL ++ LTK +I P++V Sbjct: 186 TCRDVVKEVAKIIYIVHDEVKDKAFELELSWVGELTKGRHEIVPKDV 232 >5FMG-F nrPDB Length = 254 Score = 137 bits (345), Expect = 5e-33, Method: Compositional matrix adjust. Identities = 86/248 (34%), Positives = 141/248 (56%), Gaps = 11/248 (4%) Query: 9 YDRAITVFSPEGRLYQVEYAREAVRRGTTAIGIACKDGVVLAVDRRITSKLVKIRSIEKI 68 YD ++SPEGRLYQVEYA EA+++GT A+ I KD VV++ ++ SKL + EKI Sbjct: 6 YDTDNIIYSPEGRLYQVEYASEAIKQGTCAVAIKSKDYVVVSGLKKCISKLSFPQ--EKI 63 Query: 69 FQIDDHVAAATSGLVADARVLIDRARLEAQIYRLTYGEEISIEMLAKKICDIKQAYTQHG 128 F+IDD++ + SG+ +DA+VL + E ++ Y E I+IE L + + D Q TQ Sbjct: 64 FKIDDYIGISMSGITSDAKVLTKFMQNECLSHKFLYNENINIESLVRSVADKYQKNTQKS 123 Query: 129 GVRPFGVSLLIAGIDKNEARLFETDPSGALIEYKATAIGSGRPVVMELLEKEYR--DDIT 186 R FGV L+IA NE +FET P+G+ EY A + G+ LEK ++ + Sbjct: 124 SKRAFGVGLMIAAY-HNEPCIFETRPNGSYFEYDALSFGARSHASKTYLEKNLHLFEECS 182 Query: 187 LDEGLELAITAL---TKANEDIKPENVDVCIITVKDAQFKKIPVEEIKKLIEKVKKKLNE 243 L+E + + AL + ++ N + ++ K+ +++I ++++ + KV K++ Sbjct: 183 LEELILHCLKALKCSLSSESELTISNTALAVVG-KNHPWQEISSLQLEEYLSKV--KMDA 239 Query: 244 ENKKEEEN 251 E ++ EEN Sbjct: 240 EQEQVEEN 247 >5FMG-A nrPDB Length = 260 Score = 129 bits (325), Expect = 9e-31, Method: Compositional matrix adjust. Identities = 86/259 (33%), Positives = 138/259 (53%), Gaps = 21/259 (8%) Query: 3 MVPPS--AYDRAITVFSPEGRLYQVEYAREAVRR-GTTAIGIACKDGVVLAVDRRITS-- 57 MV PS YDR +T+FSP+G LYQ+EYA +AV+ T++G+ ++ V+ +++ + Sbjct: 1 MVRPSQSMYDRHLTIFSPDGNLYQIEYAIKAVKNTNITSVGVKGENCAVIISQKKMATQY 60 Query: 58 ----KLVKIRSIEKIFQIDDHVAAATSGLVADARVLIDRARLEAQIYRLTYGEEISIEML 113 KL+ +I I+ I D + + G+ D ++ +AR EA + + G ++ E L Sbjct: 61 ISQDKLLDYNNITNIYNITDEIGCSMVGMPGDCLSMVYKARSEASEFLYSNGYNVNAETL 120 Query: 114 AKKICDIKQAYTQHGGVRPFGVSLLIAGID-KNEARLFETDPSGALIEYKATAIGSGR-- 170 + ICD Q YTQH +R S +I GID N+ LF+ DPSG Y+A IG+ Sbjct: 121 CRNICDKIQVYTQHAYMRLHACSGMIIGIDENNKPELFKFDPSGFCAGYRACVIGNKEQE 180 Query: 171 --PVVMELLEKEYR--DDITLDEGLE----LAITAL-TKANEDIKPENVDVCIITVKDAQ 221 V+ LLEK + T+DE + LAI AL T D+K ++V I++ K+ Sbjct: 181 SISVLERLLEKRKKKIQQETIDEDIRNTTILAIEALQTILAFDLKASEIEVAIVSTKNRN 240 Query: 222 FKKIPVEEIKKLIEKVKKK 240 F +I +EI + + ++ Sbjct: 241 FTQISEKEIDNYLTYIAER 259 >5FMG-G nrPDB Length = 252 Score = 127 bits (318), Expect = 6e-30, Method: Compositional matrix adjust. Identities = 59/189 (31%), Positives = 106/189 (56%), Gaps = 3/189 (1%) Query: 7 SAYDRAITVFSPEGRLYQVEYAREAVRRGTTAIGIACKDGVVLAV--DRRITSKLVKIRS 64 + YD +++ FSP+GRLYQVEY +++ TA+ + CKDG++ +K++K S Sbjct: 6 AGYDLSVSTFSPDGRLYQVEYIYKSINNNNTALCLECKDGIICCCINSNMDKNKMIKKNS 65 Query: 65 IEKIFQIDDHVAAATSGLVADARVLIDRARLEAQIYRLTYGEEISIEMLAKKICDIKQAY 124 +I+ +++++ SG DAR +IDRAR EA Y + I + +L +I AY Sbjct: 66 YNRIYHVNNNIIITYSGFDGDARNIIDRARSEANTYYYNFHTNIPLHILVNRISLYIHAY 125 Query: 125 TQHGGVRPFGVSLLIAGID-KNEARLFETDPSGALIEYKATAIGSGRPVVMELLEKEYRD 183 T + +RPF S++I+ + K++ ++ +P+GA +Y IG + + +EK+ Sbjct: 126 TLYWHMRPFAASIIISSFNEKDKGDIYCIEPNGACYKYSGIVIGKNKEMFKTEIEKKDYK 185 Query: 184 DITLDEGLE 192 DI + + +E Sbjct: 186 DINVRDAIE 194 >5T0I-L nrPDB Length = 268 Score = 126 bits (317), Expect = 8e-30, Method: Compositional matrix adjust. Identities = 79/258 (30%), Positives = 138/258 (53%), Gaps = 9/258 (3%) Query: 9 YDRAITVFSPEGRLYQVEYAREAVRRGTTAIGIACKDGVVLAVDRRITSKLVKIRSIEKI 68 YD +TV+SP+GR++Q+EYA EAV++G+ +G+ K VL +R S+L + +KI Sbjct: 11 YDNDVTVWSPQGRIHQIEYAMEAVKQGSATVGLKSKTHAVLVALKRAQSELAAHQ--KKI 68 Query: 69 FQIDDHVAAATSGLVADARVLIDRARLEAQIYRLTYGEEISIEMLAKKICDIKQAYTQHG 128 +D+H+ + +GL ADAR+L + R E R + + + L I Q TQ Sbjct: 69 LHVDNHIGISIAGLTADARLLCNFMRQECLDSRFVFDRPLPVSRLVSLIGSKTQIPTQRY 128 Query: 129 GVRPFGVSLLIAGIDKNEARLFETDPSGALIEYKATAIGSGRPVVMELLEKEYRD--DIT 186 G RP+GV LLIAG D +F+T PS + +A +IG+ LE+ + + Sbjct: 129 GRRPYGVGLLIAGYDDMGPHIFQTCPSANYFDCRAMSIGARSQSARTYLERHMSEFMECN 188 Query: 187 LDEGLELAITALTK---ANEDIKPENVDVCIITVKDAQFKKIPVEEIKKLIEKVKKKLNE 243 L+E ++ + AL + A +D+ +NV + I+ KD +F +++ +E ++++ + Sbjct: 189 LNELVKHGLRALRETLPAEQDLTTKNVSIGIVG-KDLEFTIYDDDDVSPFLEGLEER-PQ 246 Query: 244 ENKKEEENREETKEKQEE 261 + + +E EK +E Sbjct: 247 RKAQPAQPADEPAEKADE 264 >3NZW-E nrPDB Length = 234 Score = 124 bits (310), Expect = 6e-29, Method: Compositional matrix adjust. Identities = 78/232 (33%), Positives = 123/232 (53%), Gaps = 9/232 (3%) Query: 9 YDRAITVFSPEGRLYQVEYAREAVRRGTTAIGIACKDGVVLAVDRRITSKLVKIRSIEKI 68 YD FSP GRL+QVEYA EA+++G+ +G+ VL +R +L + +KI Sbjct: 6 YDGDTVTFSPTGRLFQVEYALEAIKQGSVTVGLRSNTHAVLVALKRNADELSSYQ--KKI 63 Query: 69 FQIDDHVAAATSGLVADARVLIDRARLEAQIYRLTYGEEISIEMLAKKICDIKQAYTQHG 128 + D+H+ + +GL DARVL + R + L + ++++E +CD Q TQ Sbjct: 64 IKCDEHMGLSLAGLAPDARVLSNYLRQQCNYSSLVFNRKLAVERAGHLLCDKAQKNTQSY 123 Query: 129 GVRPFGVSLLIAGIDKNEARLFETDPSGALIEYKATAIGS---GRPVVME-LLEKEYRDD 184 G RP+GV LLI G DK+ A L E PSG + E TAIG+ G +E L+ + D Sbjct: 124 GGRPYGVGLLIIGYDKSGAHLLEFQPSGNVTELYGTAIGARSQGAKTYLERTLDTFIKID 183 Query: 185 ITLDEGLELAITALTKA--NEDIKPENVDVCIITVKDAQFKKIPVEEIKKLI 234 DE ++ + A++++ +E + +N+ + I+ KD F E + K I Sbjct: 184 GNPDELIKAGVEAISQSLRDESLTVDNLSIAIVG-KDTPFTIYDGEAVAKYI 234 >5L5W-G nrPDB Length = 252 Score = 115 bits (287), Expect = 3e-26, Method: Compositional matrix adjust. Identities = 70/202 (34%), Positives = 113/202 (55%), Gaps = 9/202 (4%) Query: 9 YDRAITVFSPEGRLYQVEYAREAVRR-GTTAIGIACKDGVVLAVDRRITSKLVKIRSIEK 67 YDR IT+FSPEGRLYQVEYA +A + ++ + KD V+ +++ KL+ ++ Sbjct: 12 YDRHITIFSPEGRLYQVEYAFKATNQTNINSLAVRGKDCTVVISQKKVPDKLLDPTTVSY 71 Query: 68 IFQIDDHVAAATSGLVADARVLIDRARLEAQIYRLTYGEEISIEMLAKKICDIKQAYTQH 127 IF I + +G + DAR RA+ EA +R YG ++ ++LAK++ ++ Q YTQ Sbjct: 72 IFCISRTIGMVVNGPIPDARNAALRAKAEAAEFRYKYGYDMPCDVLAKRMANLSQIYTQR 131 Query: 128 GGVRPFGVSLLIAGIDKNEA-RLFETDPSGALIEYKATAIGSGRPVVMELLEKEYR---- 182 +RP GV L +D+ +++TDP+G + YKATA G + + LE ++ Sbjct: 132 AYMRPLGVILTFVSVDEELGPSIYKTDPAGYYVGYKATATGPKQQEITTNLENHFKKSKI 191 Query: 183 DDI---TLDEGLELAITALTKA 201 D I + ++ +E AIT + A Sbjct: 192 DHINEESWEKVVEFAITHMIDA 213 >3IPM-H nrPDB Length = 217 Score = 114 bits (284), Expect = 5e-26, Method: Compositional matrix adjust. Identities = 68/211 (32%), Positives = 117/211 (55%), Gaps = 9/211 (4%) Query: 30 EAVRRGTTAIGIACKDGVVLAVDRRITS-KLVKIRSIEKIFQIDDHVAAATSGLVADARV 88 + + GTT +GI KD V++A +RR+T + ++ +K+FQID + +GLV DA+V Sbjct: 3 QTLETGTTTVGITLKDAVIMATERRVTMENFIMHKNGKKLFQIDTYTGMTIAGLVGDAQV 62 Query: 89 LIDRARLEAQIYRLTYGEEISIEMLAKKICDIKQAYTQHGGVRPFGVSLLIAGIDKNEAR 148 L+ + E ++YRL + IE +A + ++ P+ V LL+ GID Sbjct: 63 LVRYMKAELELYRLQRRVNMPIEAVATLLSNMLNQVKYM----PYMVQLLVGGID-TAPH 117 Query: 149 LFETDPSGALIEYKATAIGSGRPVVMELLEKEYRDDITLDEGLELAITALTKANE--DIK 206 +F D +G +E + GSG P V +LE +Y + +T+DEG++L I A++ A + Sbjct: 118 VFSIDAAGGSVEDIYASTGSGSPFVYGVLESQYSEKMTVDEGVDLVIRAISAAKQRDSAS 177 Query: 207 PENVDVCIITVKDAQFKKIPVEEIKKLIEKV 237 +DV +IT KD + ++P ++I+ I K+ Sbjct: 178 GGMIDVAVITRKDG-YVQLPTDQIESRIRKL 207 >6HEC-1 nrPDB Length = 202 Score = 102 bits (254), Expect = 2e-22, Method: Compositional matrix adjust. Identities = 62/206 (30%), Positives = 110/206 (53%), Gaps = 6/206 (2%) Query: 36 TTAIGIACKDGVVLAVDRRIT-SKLVKIRSIEKIFQIDDHVAAATSGLVADARVLIDRAR 94 TT +G+ CKDGVV+A ++R T + ++ +KI+QI D +A T+G V DA+ L + Sbjct: 1 TTTVGLVCKDGVVMATEKRATMGNFIASKAAKKIYQIADRMAMTTAGSVGDAQFLARIIK 60 Query: 95 LEAQIYRLTYGEEISIEMLAKKICDIKQAYTQHGGVRPFGVSLLIAGIDKNEARLFETDP 154 +EA +Y + + ++ +A ++ +Y P+ V LLI GID ++ DP Sbjct: 61 IEANLYEIRRERKPTVRAIATLTSNLLNSYRYF----PYLVQLLIGGIDSEGKSIYSIDP 116 Query: 155 SGALIEYK-ATAIGSGRPVVMELLEKEYRDDITLDEGLELAITALTKANEDIKPENVDVC 213 G IE K A GSG +LE + +I +DE +ELA+ A+ A + + Sbjct: 117 IGGAIEEKDIVATGSGSLTAYGVLEDRFTPEIGVDEAVELAVRAIYSAMKRDSASGDGID 176 Query: 214 IITVKDAQFKKIPVEEIKKLIEKVKK 239 ++ + + +F + EE+++++ K +K Sbjct: 177 VVKITEDEFYQYSPEEVEQILAKFRK 202 >3H4P-a nrPDB Length = 219 Score = 100 bits (249), Expect = 6e-22, Method: Compositional matrix adjust. Identities = 69/207 (33%), Positives = 113/207 (54%), Gaps = 11/207 (5%) Query: 36 TTAIGIACKDGVVLAVDRRIT-SKLVKIRSIEKIFQIDDHVAAATSGLVADARVLIDRAR 94 TT +G+ C D V+LA D+R + LV + +K+++IDD++A +G V DA+ ++ Sbjct: 2 TTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIVRLLI 61 Query: 95 LEAQIYRLTYGEEISIEMLAKKICDIKQAYTQHGGVRPFGVSLLIAGIDKNE-ARLFETD 153 EA++Y++ G I A + +I + PF ++I G D E A+LF D Sbjct: 62 AEAKLYKMRTGRNIPPLACATLLSNILHSSRMF----PFLTQIIIGGYDLLEGAKLFSLD 117 Query: 154 PSGALIEYKA-TAIGSGRPVVMELLEKEYRDDITLDEGLELAITALTKANE--DIKPENV 210 P G + E K TA GSG P+ +LE Y D++++EG++LA+ AL A E + Sbjct: 118 PLGGMNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERDTFSGNGI 177 Query: 211 DVCIITVKDAQFKKIPVEEIKKLIEKV 237 + +IT KD K EEI+K+++ + Sbjct: 178 SLAVIT-KDG-VKIFEDEEIEKILDSM 202 >3UNH-H nrPDB Length = 234 Score = 90.1 bits (222), Expect = 8e-19, Method: Compositional matrix adjust. Identities = 58/203 (28%), Positives = 102/203 (50%), Gaps = 11/203 (5%) Query: 36 TTAIGIACKDGVVLAVDRRITS-KLVKIRSIEKIFQIDDHVAAATSGLVADARVLIDRAR 94 TT G+ +DGV+L D R T+ +V +S EKI I + +G+ AD + A Sbjct: 1 TTIAGLVFRDGVILGADTRATNDSVVADKSCEKIHFIAPKIYCCGAGVAADTEMTTRMAA 60 Query: 95 LEAQIYRLTYGEEISIEMLAKKICDIKQAYTQHGGVRPFGVSLLIAGIDKNEARLFETDP 154 + +++ L+ G E + + + + Y H G SL++ G+D N +L+E P Sbjct: 61 SKMELHALSTGREPRVATVTRILRQTLFRYQGH-----VGASLVVGGVDLNGPQLYEVHP 115 Query: 155 SGALIEYKATAIGSGRPVVMELLEKEYRDDITLDEGLELAITALTKA--NEDIKPENVDV 212 G+ TA+GSG+ + LLE ++ ++TL+ EL + A+T ++ NVD Sbjct: 116 HGSYSRLPFTALGSGQGAAVALLEDRFQPNMTLEAAQELLVEAITAGILSDLGSGGNVDA 175 Query: 213 CIITVKDAQFKK---IPVEEIKK 232 C+IT A+ ++ P E +++ Sbjct: 176 CVITAGGAKLQRALSTPTEPVQR 198 >5FMG-I nrPDB Length = 229 Score = 81.3 bits (199), Expect = 4e-16, Method: Compositional matrix adjust. Identities = 53/197 (26%), Positives = 97/197 (49%), Gaps = 9/197 (4%) Query: 36 TTAIGIACKDGVVLAVDRRIT-SKLVKIRSIEKIFQIDDHVAAATSGLVADARVLIDRAR 94 TT G+ C++ V+L D R T +V ++ K+ I ++ A +G+ D + Sbjct: 1 TTICGLVCQNAVILGADTRATEGPIVADKNCSKLHYISKNIWCAGAGVAGDLEHTTLWLQ 60 Query: 95 LEAQIYRLTYGEEISIEMLAKKICDIKQAYTQHGGVRPFGVSLLIAGIDKNEARLFETDP 154 +++RL + + M ++ Q ++ G + ++++ G+D N +L+ P Sbjct: 61 HNVELHRLNTNTQPRVSMCVSRL---TQELFKYQGYKV--CAIVLGGVDVNGPQLYGIHP 115 Query: 155 SGALIEYKATAIGSGRPVVMELLEKEYRDDITLDEGLELAITALTKA--NEDIKPENVDV 212 G+ TA+GSG M +LE +YRD++T++EG L A+ N+ NVD+ Sbjct: 116 HGSSCLLPFTALGSGSLNAMAVLEAKYRDNMTIEEGKNLVCEAICAGIFNDLGSGGNVDI 175 Query: 213 CIITVKDAQFKKIPVEE 229 C+IT KD+ P +E Sbjct: 176 CVIT-KDSYQHIRPYKE 191 >6AVO-B nrPDB Length = 234 Score = 79.0 bits (193), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 55/203 (27%), Positives = 97/203 (47%), Gaps = 11/203 (5%) Query: 36 TTAIGIACKDGVVLAVDRRITS-KLVKIRSIEKIFQIDDHVAAATSGLVADARVLIDRAR 94 TT G+ +DGV+L D R T+ +V +S EKI I + +G+ ADA + Sbjct: 1 TTIAGLVFQDGVILGADTRATNDSVVADKSCEKIHFIAPKIYCCGAGVAADAEMTTRMVA 60 Query: 95 LEAQIYRLTYGEEISIEMLAKKICDIKQAYTQHGGVRPFGVSLLIAGIDKNEARLFETDP 154 + +++ L+ G E + + + + Y H G SL++ G+D +L+ P Sbjct: 61 SKMELHALSTGREPRVATVTRILRQTLFRYQGH-----VGASLIVGGVDLTGPQLYGVHP 115 Query: 155 SGALIEYKATAIGSGRPVVMELLEKEYRDDITLDEGLELAITALTKA--NEDIKPENVDV 212 G+ TA+GSG+ + +LE ++ ++TL+ L + A+T + NVD Sbjct: 116 HGSYSRLPFTALGSGQDAALAVLEDRFQPNMTLEAAQGLLVEAVTAGILGDLGSGGNVDA 175 Query: 213 CIITVKDAQFKKI---PVEEIKK 232 C+IT A+ + P E +K+ Sbjct: 176 CVITKTGAKLLRTLSSPTEPVKR 198 >6HV7-H nrPDB Length = 226 Score = 72.4 bits (176), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 55/195 (28%), Positives = 94/195 (48%), Gaps = 17/195 (8%) Query: 36 TTAIGIACKDGVVLAVDRRITS-KLVKIRSIEKIFQIDDHVAAATSGLVADARVLIDRAR 94 TT G+ +DGV+L D R T+ +V +S EKI I + +G+ ADA + Sbjct: 1 TTIAGLVFQDGVILGADTRATNDSVVADKSCEKIHFIAPKIYCCGAGVAADAEAVTQLIG 60 Query: 95 LEAQIYRLTYGEE----ISIEMLAKKICDIKQAYTQHGGVRPFGVSLLIAGIDKNEARLF 150 +++ L E +++ML + + Y H G L++AG+D + LF Sbjct: 61 SNIELHSLYTSREPRVVSALQMLKQHLFK----YQGH-----IGAYLIVAGVDPTGSHLF 111 Query: 151 ETDPSGALIEYKATAIGSGRPVVMELLEKEYRDDITLDEGLELAITALTKA--NEDIKPE 208 G+ ++GSG M +LE ++ D+T +E ++LA A+ N+ Sbjct: 112 SIHAHGSTDVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDLGSGS 171 Query: 209 NVDVCIITV-KDAQF 222 NVDVC++ + KDA++ Sbjct: 172 NVDVCVMEIGKDAEY 186 >5FGI-H nrPDB Length = 244 Score = 71.6 bits (174), Expect = 3e-13, Method: Compositional matrix adjust. Identities = 53/201 (26%), Positives = 95/201 (47%), Gaps = 17/201 (8%) Query: 30 EAVRRGTTAIGIACKDGVVLAVDRRIT-SKLVKIRSIEKIFQIDDHVAAATSGLVADARV 88 +A G T +G+ +GVV+A D R T +V ++ K+ +I + A +G AD Sbjct: 7 KATSTGATIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEA 66 Query: 89 LIDRARLEAQIYRLTYGEE----ISIEMLAKKICDIKQAYTQHGGVRPFGVSLLIAGIDK 144 + +++ L E +++ML + + Y H G L++AG+D Sbjct: 67 VTQLIGSNIELHSLYTSREPRVVSALQMLKQHLFK----YQGH-----IGAYLIVAGVDP 117 Query: 145 NEARLFETDPSGALIEYKATAIGSGRPVVMELLEKEYRDDITLDEGLELAITALTKA--N 202 + LF G+ ++GSG M +LE ++ D+T +E ++LA A+ N Sbjct: 118 TGSHLFSIHAHGSTDVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWN 177 Query: 203 EDIKPENVDVCIITV-KDAQF 222 + NVDVC++ + KDA++ Sbjct: 178 DLGSGSNVDVCVMEIGKDAEY 198 >3UNF-K nrPDB Length = 204 Score = 70.1 bits (170), Expect = 9e-13, Method: Compositional matrix adjust. Identities = 51/205 (24%), Positives = 95/205 (46%), Gaps = 11/205 (5%) Query: 36 TTAIGIACKDGVVLAVDRRIT--SKLVKIRSIEKIFQIDDHVAAATSGLVADARVLIDRA 93 TT + + GV++AVD R T S + +R + K+ +I+ ++ SG AD + Sbjct: 1 TTTLAFKFQHGVIVAVDSRATAGSYISSLR-MNKVIEINPYLLGTMSGCAADCQYWERLL 59 Query: 94 RLEAQIYRLTYGEEISIEMLAKKICDIKQAYTQHGGVRPFGVSL--LIAGIDKNEARLFE 151 E ++Y L GE IS+ +K + ++ Y R G+S+ +I G DK L+ Sbjct: 60 AKECRLYYLRNGERISVSAASKLLSNMMLQY------RGMGLSMGSMICGWDKKGPGLYY 113 Query: 152 TDPSGALIEYKATAIGSGRPVVMELLEKEYRDDITLDEGLELAITALTKANEDIKPENVD 211 D +G + + + GSG +++ YR D++ +E +L A+ A Sbjct: 114 VDDNGTRLSGQMFSTGSGNTYAYGVMDSGYRQDLSPEEAYDLGRRAIAYATHRDNYSGGV 173 Query: 212 VCIITVKDAQFKKIPVEEIKKLIEK 236 V + +K+ + K+ ++ L+ K Sbjct: 174 VNMYHMKEDGWVKVESSDVSDLLYK 198 >5FMG-L nrPDB Length = 211 Score = 68.9 bits (167), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 44/167 (26%), Positives = 79/167 (47%), Gaps = 5/167 (2%) Query: 36 TTAIGIACKDGVVLAVDRRIT-SKLVKIRSIEKIFQIDDHVAAATSGLVADARVLIDRAR 94 TT + KDG+++AVD R + + +++EKI +I+ ++ +G AD Sbjct: 1 TTTLAFKFKDGIIVAVDSRASMGSFISSQNVEKIIEINKNILGTMAGGAADCLYWEKYLG 60 Query: 95 LEAQIYRLTYGEEISIEMLAKKICDIKQAYTQHGGVRPFGVSLLIAGIDKNEARLFETDP 154 +IY L E+IS+ + + +I Y +G ++++G D +F D Sbjct: 61 KIIKIYELRNNEKISVRAASTILSNILYQYKGYG----LCCGIILSGYDHTGFNMFYVDD 116 Query: 155 SGALIEYKATAIGSGRPVVMELLEKEYRDDITLDEGLELAITALTKA 201 SG +E + GSG +L+ Y ++ LD+ +ELA A+ A Sbjct: 117 SGKKVEGNLFSCGSGSTYAYSILDSAYDYNLNLDQAVELARNAIYHA 163 >6AVO-C nrPDB Length = 204 Score = 65.9 bits (159), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 46/206 (22%), Positives = 91/206 (44%), Gaps = 9/206 (4%) Query: 36 TTAIGIACKDGVVLAVDRRITS-KLVKIRSIEKIFQIDDHVAAATSGLVADARVLIDRAR 94 TT + + GV+ AVD R ++ + + K+ +I+ ++ SG AD + Sbjct: 1 TTTLAFKFQHGVIAAVDSRASAGSYISALRVNKVIEINPYLLGTMSGCAADCQYWERLLA 60 Query: 95 LEAQIYRLTYGEEISIEMLAKKICDIKQAYTQHGGVRPFGVSL--LIAGIDKNEARLFET 152 E ++Y L GE IS+ +K + ++ Y R G+S+ +I G DK L+ Sbjct: 61 KECRLYYLRNGERISVSAASKLLSNMMCQY------RGMGLSMGSMICGWDKKGPGLYYV 114 Query: 153 DPSGALIEYKATAIGSGRPVVMELLEKEYRDDITLDEGLELAITALTKANEDIKPENVDV 212 D G + + GSG +++ YR +++ +E +L A+ A V Sbjct: 115 DEHGTRLSGNMFSTGSGNTYAYGVMDSGYRPNLSPEEAYDLGRRAIAYATHRDSYSGGVV 174 Query: 213 CIITVKDAQFKKIPVEEIKKLIEKVK 238 + +K+ + K+ ++ L+ + + Sbjct: 175 NMYHMKEDGWVKVESTDVSDLLHQYR 200 >6EPF-2 nrPDB Length = 277 Score = 65.9 bits (159), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 50/196 (25%), Positives = 91/196 (46%), Gaps = 8/196 (4%) Query: 30 EAVRRGTTAIGIACKDGVVLAVDRRITSKLVKI-RSIEKIFQIDDHVAAATSGLVADARV 88 +A + GTT G+ KDG+VL D R T +V ++ KI I ++ +G AD + Sbjct: 38 KARKTGTTIAGVVYKDGIVLGADTRATEGMVVADKNCSKIHFISPNIYCCGAGTAADTDM 97 Query: 89 LIDRARLEAQIYRLTYGEEISIEMLAKKICDIKQAYTQHGGVRPFGVSLLIAGIDKNEAR 148 +++ LT G + + A ++ +KQ ++ G G +L++ G+D Sbjct: 98 TTQLISSNLELHSLTTGRLPRV-VTANRM--LKQMLFRYQGY--IGAALVLGGVDVTGPH 152 Query: 149 LFETDPSGALIEYKATAIGSGRPVVMELLEKEYRDDITLDEGLELAITALTKA--NEDIK 206 L+ P G+ + +GSG M + E ++R D+ +E +L A+ N+ Sbjct: 153 LYSIYPHGSTDKLPYVTMGSGSLAAMAVFEDKFRPDMEEEEAKKLVSEAIAAGIFNDLGS 212 Query: 207 PENVDVCIITVKDAQF 222 N+D+C+I+ F Sbjct: 213 GSNIDLCVISKSKLDF 228 >5L5A-K nrPDB Length = 211 Score = 65.5 bits (158), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 49/214 (22%), Positives = 93/214 (43%), Gaps = 9/214 (4%) Query: 36 TTAIGIACKDGVVLAVDRRITS-KLVKIRSIEKIFQIDDHVAAATSGLVADARVLIDRAR 94 TT + + GV+ AVD R ++ + + K+ +I+ ++ SG AD + Sbjct: 1 TTTLAFKFQHGVIAAVDSRASAGSYISALRVNKVIEINPYLLGTMSGCAADCQYWETLLA 60 Query: 95 LEAQIYRLTYGEEISIEMLAKKICDIKQAYTQHGGVRPFGVSL--LIAGIDKNEARLFET 152 E ++Y L GE IS+ +K + ++ Y R G+S+ +I G DK L+ Sbjct: 61 KECRLYYLRNGERISVSAASKLLSNMMCQY------RGMGLSMGSMICGWDKKGPGLYYV 114 Query: 153 DPSGALIEYKATAIGSGRPVVMELLEKEYRDDITLDEGLELAITALTKANEDIKPENVDV 212 D G + + GSG +L+ Y+ D+++++ L L ++ A V Sbjct: 115 DEHGTRLSGNMFSTGSGNTYAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSV 174 Query: 213 CIITVKDAQFKKIPVEEIKKLIEKVKKKLNEENK 246 + V + + ++ +L KVK++ N Sbjct: 175 NLYHVTEDGWIYHGNHDVGELFWKVKEEEGSFNN 208 >6EPF-5 nrPDB Length = 263 Score = 65.5 bits (158), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 46/209 (22%), Positives = 94/209 (44%), Gaps = 5/209 (2%) Query: 34 RGTTAIGIACKDGVVLAVDRRITSK-LVKIRSIEKIFQIDDHVAAATSGLVADARVLIDR 92 GTT + + GV++A D R T+ + ++++K+ +I+ ++ +G AD Sbjct: 58 HGTTTLAFKFQHGVIVAADSRATAGPYIASQTVKKVIEINPYLLGTMAGGAADCSFWERL 117 Query: 93 ARLEAQIYRLTYGEEISIEMLAKKICDIKQAYTQHGGVRPFGVSLLIAGIDKNEARLFET 152 + +IY L E IS+ +K + ++ Y G + +I G DK L+ Sbjct: 118 LARQCRIYELRNKERISVAAASKLLANMVYQYKGMG----LSMGTMICGWDKRGPGLYYV 173 Query: 153 DPSGALIEYKATAIGSGRPVVMELLEKEYRDDITLDEGLELAITALTKANEDIKPENVDV 212 D G I A ++GSG ++++ Y D+ ++E +LA A+ +A V Sbjct: 174 DSEGNRISGTAFSVGSGSVYAFGVMDRGYSYDLQVEEAYDLARRAIYQATYRDAYSGGAV 233 Query: 213 CIITVKDAQFKKIPVEEIKKLIEKVKKKL 241 + V++ + ++ + + L +K + Sbjct: 234 NLYHVREDGWIRVSSDNVADLHDKYTSSI 262 >5L4G-8 nrPDB Length = 277 Score = 64.3 bits (155), Expect = 5e-11, Method: Compositional matrix adjust. Identities = 51/200 (25%), Positives = 91/200 (45%), Gaps = 9/200 (4%) Query: 27 YAREAVRR-GTTAIGIACKDGVVLAVDRRITSKLVKI-RSIEKIFQIDDHVAAATSGLVA 84 Y VR+ GTT G+ KDG+VL D R T +V ++ KI I ++ +G A Sbjct: 34 YKLPKVRKTGTTIAGVVYKDGIVLGADTRATEGMVVADKNCSKIHFISPNIYCCGAGTAA 93 Query: 85 DARVLIDRARLEAQIYRLTYGEEISIEMLAKKICDIKQAYTQHGGVRPFGVSLLIAGIDK 144 D + +++ L+ G + + A ++ +KQ ++ G G +L++ G+D Sbjct: 94 DTDMTTQLISSNLELHSLSTGRLPRV-VTANRM--LKQMLFRYQGY--IGAALVLGGVDV 148 Query: 145 NEARLFETDPSGALIEYKATAIGSGRPVVMELLEKEYRDDITLDEGLELAITALTKA--N 202 L+ P G+ + +GSG M + E ++R D+ +E L A+ N Sbjct: 149 TGPHLYSIYPHGSTDKLPYVTMGSGSLAAMAVFEDKFRPDMEEEEAKNLVSEAIAAGIFN 208 Query: 203 EDIKPENVDVCIITVKDAQF 222 + N+D+C+I+ F Sbjct: 209 DLGSGSNIDLCVISKNKLDF 228 >5FMG-M nrPDB Length = 240 Score = 63.2 bits (152), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 43/163 (26%), Positives = 82/163 (50%), Gaps = 8/163 (4%) Query: 19 EGRLYQVEYAREAVRRGTTAIGIACKDGVVLAVDRRIT-SKLVKIRSIEKIFQIDDHVAA 77 GR ++ Y + G T IG+ KD V+LA D R++ S + R KI ++ D Sbjct: 23 HGRGFKRWYPY--IDNGGTVIGLTGKDYVILAADTRLSLSYSIYTRFCPKISKLTDKCII 80 Query: 78 ATSGLVADARVLIDRARLEAQIYRLTYGEEISIEMLAKKICDIKQAYTQHGGVRPFGVSL 137 +SG+ +D + L + + Q++ L + I ++A+ +C I Y++ P+ Sbjct: 81 GSSGMQSDIKTLHSLLQKKIQLFVLEHSHYPDIHVIARLLCVI--LYSRR--FFPYYAFN 136 Query: 138 LIAGID-KNEARLFETDPSGALIEYKATAIGSGRPVVMELLEK 179 ++AG+D N+ L+ D G+ E + +GSG +++ +L+ Sbjct: 137 ILAGVDENNKGVLYNYDSVGSYCEATHSCVGSGSQLILPILDN 179 >5LN3-5 nrPDB Length = 263 Score = 62.8 bits (151), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 45/204 (22%), Positives = 92/204 (45%), Gaps = 5/204 (2%) Query: 34 RGTTAIGIACKDGVVLAVDRRITSK-LVKIRSIEKIFQIDDHVAAATSGLVADARVLIDR 92 GTT + + GV++A D R T+ + ++++K+ +I+ ++ +G AD Sbjct: 58 HGTTTLAFKFRHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAADCSFWERL 117 Query: 93 ARLEAQIYRLTYGEEISIEMLAKKICDIKQAYTQHGGVRPFGVSLLIAGIDKNEARLFET 152 + +IY L E IS+ +K + ++ Y G + +I G DK L+ Sbjct: 118 LARQCRIYELRNKERISVAAASKLLANMVYQYKGMG----LSMGTMICGWDKRGPGLYYV 173 Query: 153 DPSGALIEYKATAIGSGRPVVMELLEKEYRDDITLDEGLELAITALTKANEDIKPENVDV 212 D G I ++GSG ++++ Y D+ +++ +LA A+ +A V Sbjct: 174 DSEGNRISGATFSVGSGSVYAYGVMDRGYSYDLEVEQAYDLARRAIYQATYRDAYSGGAV 233 Query: 213 CIITVKDAQFKKIPVEEIKKLIEK 236 + V++ + ++ + + L EK Sbjct: 234 NLYHVREDGWIRVSSDNVADLHEK 257 >6HUB-H nrPDB Length = 234 Score = 60.5 bits (145), Expect = 8e-10, Method: Compositional matrix adjust. Identities = 47/190 (24%), Positives = 86/190 (45%), Gaps = 8/190 (4%) Query: 36 TTAIGIACKDGVVLAVDRRITSKLVKI-RSIEKIFQIDDHVAAATSGLVADARVLIDRAR 94 TT G+ KDG+VL D R T +V ++ KI I ++ +G AD + Sbjct: 1 TTIAGVVYKDGIVLGADTRATEGMVVADKNCSKIHFISPNIYCCGAGTAADTDMTTQLIS 60 Query: 95 LEAQIYRLTYGEEISIEMLAKKICDIKQAYTQHGGVRPFGVSLLIAGIDKNEARLFETDP 154 +++ L+ G + + A ++ +KQ ++ G G +L++ G+D L+ P Sbjct: 61 SNLELHSLSTGRLPRV-VTANRM--LKQMLFRYQGY--IGAALVLGGVDVTGPHLYSIYP 115 Query: 155 SGALIEYKATAIGSGRPVVMELLEKEYRDDITLDEGLELAITALTKA--NEDIKPENVDV 212 G+ + +GSG M + E ++R D+ +E L A+ N+ N+D+ Sbjct: 116 HGSTDKLPYVTMGSGSLAAMAVFEDKFRPDMEEEEAKNLVSEAIAAGIFNDLGSGGNIDL 175 Query: 213 CIITVKDAQF 222 C+I+ F Sbjct: 176 CVISKNKLDF 185 >6EPC-1 nrPDB Length = 238 Score = 60.1 bits (144), Expect = 9e-10, Method: Compositional matrix adjust. Identities = 49/190 (25%), Positives = 80/190 (42%), Gaps = 9/190 (4%) Query: 16 FSPEGRLYQVEYAREAVRRGTTAIGIACKDGVVLAVDRRITS-KLVKIRSIEKIFQIDDH 74 F PE ++ V GTT + + GVVL D R T+ + R +K+ I DH Sbjct: 16 FGPEA--LTPDWENREVSTGTTIMAVQFDGGVVLGADSRTTTGSYIANRVTDKLTPIHDH 73 Query: 75 VAAATSGLVADARVLIDRARLEAQIYRLTYGEEISIEMLAKKICDIKQAYTQHGGVRPFG 134 + SG AD + + D + + + E + A ++ Y + Sbjct: 74 IFCCRSGSAADTQAVADAVTYQLGFHSIELNEPPLVHTAASLFKEMCYRYRED-----LM 128 Query: 135 VSLLIAGIDKNEARLFETDPSGALIEYKATAIG-SGRPVVMELLEKEYRDDITLDEGLEL 193 ++IAG D E + P G ++ ++ AIG SG + ++ YR+ +T DE L+ Sbjct: 129 AGIIIAGWDPQEGGQVYSVPMGGMMVRQSFAIGGSGSSYIYGYVDATYREGMTKDECLQF 188 Query: 194 AITALTKANE 203 AL A E Sbjct: 189 TANALALAME 198 >3UNB-K nrPDB Length = 205 Score = 59.7 bits (143), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 45/202 (22%), Positives = 91/202 (45%), Gaps = 5/202 (2%) Query: 36 TTAIGIACKDGVVLAVDRRITS-KLVKIRSIEKIFQIDDHVAAATSGLVADARVLIDRAR 94 TT + GV++A D R T+ + ++++K+ +I+ ++ +G AD Sbjct: 1 TTTLAFKFLHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAADCSFWERLLA 60 Query: 95 LEAQIYRLTYGEEISIEMLAKKICDIKQAYTQHGGVRPFGVSLLIAGIDKNEARLFETDP 154 + +IY L E IS+ +K + ++ Y G + +I G DK L+ D Sbjct: 61 RQCRIYELRNKERISVAAASKLLANMVYQYKGMG----LSMGTMICGWDKRGPGLYYVDS 116 Query: 155 SGALIEYKATAIGSGRPVVMELLEKEYRDDITLDEGLELAITALTKANEDIKPENVDVCI 214 G I A ++GSG ++++ Y D+ ++E +LA A+ +A V + Sbjct: 117 EGNRISGTAFSVGSGSVYAYGVMDRGYSYDLKVEEAYDLARRAIYQATYRDAYSGGAVNL 176 Query: 215 ITVKDAQFKKIPVEEIKKLIEK 236 V++ + ++ + + L +K Sbjct: 177 YHVREDGWIRVSSDNVADLHDK 198 >5L64-K nrPDB Length = 211 Score = 59.7 bits (143), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 47/214 (21%), Positives = 95/214 (44%), Gaps = 9/214 (4%) Query: 36 TTAIGIACKDGVVLAVDRRITSK-LVKIRSIEKIFQIDDHVAAATSGLVADARVLIDRAR 94 TT + + GV++A D R T+ + ++++K+ +I+ ++ +G AD Sbjct: 1 TTTLAFKFRHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAADCSFWERLLA 60 Query: 95 LEAQIYRLTYGEEISIEMLAKKICDIKQAYTQHGGVRPFGVSL--LIAGIDKNEARLFET 152 + +IY L E IS+ +K + ++ Y + G+S+ +I G DK L+ Sbjct: 61 RQCRIYELRNKERISVAAASKLLANMVYQY------KGMGLSMGTMICGWDKRGPGLYYV 114 Query: 153 DPSGALIEYKATAIGSGRPVVMELLEKEYRDDITLDEGLELAITALTKANEDIKPENVDV 212 D G I ++GSG +L+ Y+ D+++++ L L ++ A V Sbjct: 115 DSEGNRISGATFSVGSGSVYAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSV 174 Query: 213 CIITVKDAQFKKIPVEEIKKLIEKVKKKLNEENK 246 + V + + ++ +L KVK++ N Sbjct: 175 NLYHVTEDGWIYHGNHDVGELFWKVKEEEGSFNN 208 >3NZW-L nrPDB Length = 241 Score = 59.7 bits (143), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 44/154 (28%), Positives = 75/154 (48%), Gaps = 15/154 (9%) Query: 34 RGTTAIGIACKDGVVLAVD-RRITSKLVKIRSIEKIFQIDDHVAAATSGLVADARVLIDR 92 G T +GIA +D VLA D R IT + R K+F D++ + +G AD L+ R Sbjct: 27 NGGTILGIAGEDFAVLAGDTRNITDYSINSRYEPKVFDCGDNIVMSANGFAADGDALVKR 86 Query: 93 ARLEAQIYRLTYGE-EISIEMLAKKICDIKQAYTQH--GGVR--PFGVSLLIAGIDKN-E 146 + + Y + + ++SI A+ I QH G R P+ V +IAG+D++ + Sbjct: 87 FKNSVKWYHFDHNDKKLSINSAARNI--------QHLLYGKRFFPYYVHTIIAGLDEDGK 138 Query: 147 ARLFETDPSGALIEYKATAIGSGRPVVMELLEKE 180 ++ DP G+ + A G+ ++M L+ + Sbjct: 139 GAVYSFDPVGSYEREQCRAGGAAASLIMPFLDNQ 172 >5FGE-J nrPDB Length = 198 Score = 56.2 bits (134), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 43/159 (27%), Positives = 77/159 (48%), Gaps = 7/159 (4%) Query: 39 IGIACKDGVVLAVDRRITSKLVKIR-SIEKIFQIDDHVAAATSGLVADARVLIDRARLEA 97 +GI +D V+LA + +T + ++ S +K Q+ H + +G D + + Sbjct: 5 LGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQANI 64 Query: 98 QIYRLTYGEEISIEMLAKKICDIKQAYTQH-GGVRPFGVSLLIAGIDK--NEARLFETDP 154 Q+Y + E+S + ++ + +Q + RP+ V++LI G DK N+ L++ D Sbjct: 65 QLYSIREDYELSPQAVSSFV---RQELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQIDY 121 Query: 155 SGALIEYKATAIGSGRPVVMELLEKEYRDDITLDEGLEL 193 G +E A G LL+ YR D+T +EGL+L Sbjct: 122 LGTKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDL 160 >3NZW-K nrPDB Length = 287 Score = 55.8 bits (133), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 43/217 (19%), Positives = 96/217 (44%), Gaps = 6/217 (2%) Query: 32 VRRGTTAIGIACKDGVVLAVDRRITS-KLVKIRSIEKIFQIDDHVAAATSGLVADARVLI 90 + GTT + + G+++AVD R T+ V ++++K+ +I+ + +G AD + Sbjct: 72 IAHGTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWE 131 Query: 91 DRARLEAQIYRLTYGEEISIEMLAKKICDIKQAYTQHGGVRPFGVSLLIAGIDKNEA-RL 149 + +++ L E IS+ +K + ++ Y G + +I G + E + Sbjct: 132 TWLGSQCRLHELREKERISVAAASKILSNLVYQYKGAG----LSMGTMICGYTRKEGPTI 187 Query: 150 FETDPSGALIEYKATAIGSGRPVVMELLEKEYRDDITLDEGLELAITALTKANEDIKPEN 209 + D G ++ +GSG+ +L+ Y+ D+++++ L L ++ A Sbjct: 188 YYVDSDGTRLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSG 247 Query: 210 VDVCIITVKDAQFKKIPVEEIKKLIEKVKKKLNEENK 246 V + V + + ++ +L KVK++ N Sbjct: 248 GSVNLYHVTEDGWIYHGNHDVGELFWKVKEEEGSFNN 284 >3WXR-K nrPDB Length = 238 Score = 55.5 bits (132), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 43/159 (27%), Positives = 77/159 (48%), Gaps = 7/159 (4%) Query: 39 IGIACKDGVVLAVDRRITSKLVKIR-SIEKIFQIDDHVAAATSGLVADARVLIDRARLEA 97 +GI +D V+LA + +T + ++ S +K Q+ H + +G D + + Sbjct: 5 LGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQANI 64 Query: 98 QIYRLTYGEEISIEMLAKKICDIKQAYTQH-GGVRPFGVSLLIAGIDK--NEARLFETDP 154 Q+Y + E+S + ++ + +Q + RP+ V++LI G DK N+ L++ D Sbjct: 65 QLYSIREDYELSPQAVSSFV---RQELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQIDY 121 Query: 155 SGALIEYKATAIGSGRPVVMELLEKEYRDDITLDEGLEL 193 G +E A G LL+ YR D+T +EGL+L Sbjct: 122 LGTKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDL 160 >5MPC-h nrPDB Length = 215 Score = 54.3 bits (129), Expect = 5e-08, Method: Compositional matrix adjust. Identities = 42/175 (24%), Positives = 83/175 (47%), Gaps = 14/175 (8%) Query: 32 VRRGTTAIGIACKDGVVLAVDRRITS-KLVKIRSIEKIFQIDDHVAAATSGLVADARVLI 90 V GT+ + + KDGV+L D R T+ + R +K+ ++ D + SG AD + + Sbjct: 16 VSLGTSIMAVTFKDGVILGADSRTTTGAYIANRVTDKLTRVHDKIWCCRSGSAADTQAIA 75 Query: 91 DRARLEAQIYRLTYGEEISIEMLA---KKICDIKQAYTQHGGVRPFGVSLLIAGI-DKNE 146 D + ++Y YG S E A K++C + G +++AG DKN+ Sbjct: 76 DIVQYHLELYTSQYGTP-STETAASVFKELCYENKDNLTAG--------IIVAGYDDKNK 126 Query: 147 ARLFETDPSGALIEYKATAIGSGRPVVMELLEKEYRDDITLDEGLELAITALTKA 201 ++ G++ + GSG + +K +R++++ +E ++ +L++A Sbjct: 127 GEVYTIPLGGSVHKLPYAIAGSGSTFIYGYCDKNFRENMSKEETVDFIKHSLSQA 181 >5GJQ-a nrPDB Length = 239 Score = 53.9 bits (128), Expect = 6e-08, Method: Compositional matrix adjust. Identities = 46/190 (24%), Positives = 80/190 (42%), Gaps = 9/190 (4%) Query: 16 FSPEGRLYQVEYAREAVRRGTTAIGIACKDGVVLAVDRRITS-KLVKIRSIEKIFQIDDH 74 + PE + ++ V GTT + + GVVL D R T+ + R +K+ I D Sbjct: 17 WGPEA--FTPDWESREVSTGTTIMAVQFDGGVVLGADSRTTTGSYIANRVTDKLTPIHDR 74 Query: 75 VAAATSGLVADARVLIDRARLEAQIYRLTYGEEISIEMLAKKICDIKQAYTQHGGVRPFG 134 + SG AD + + D + + + E + A ++ Y + Sbjct: 75 IFCCRSGSAADTQAVADAVTYQLGFHSIELNEPPLVHTAASLFKEMCYRYRED-----LM 129 Query: 135 VSLLIAGIDKNEARLFETDPSGALIEYKATAIG-SGRPVVMELLEKEYRDDITLDEGLEL 193 ++IAG D E + P G ++ ++ AIG SG + ++ YR+ +T +E L+ Sbjct: 130 AGIIIAGWDPQEGGQVYSVPMGGMMVRQSFAIGGSGSSYIYGYVDATYREGMTKEECLQF 189 Query: 194 AITALTKANE 203 AL A E Sbjct: 190 TANALALAME 199 >5CZ8-K nrPDB Length = 221 Score = 52.8 bits (125), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 42/217 (19%), Positives = 95/217 (43%), Gaps = 6/217 (2%) Query: 32 VRRGTTAIGIACKDGVVLAVDRRITS-KLVKIRSIEKIFQIDDHVAAATSGLVADARVLI 90 + GTT + + G+++AVD R T+ V ++++ + +I+ + +G AD + Sbjct: 6 IAHGTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKAVIEINPFLLGTMAGGAADCQFWE 65 Query: 91 DRARLEAQIYRLTYGEEISIEMLAKKICDIKQAYTQHGGVRPFGVSLLIAGIDKNEA-RL 149 + +++ L E IS+ +K + ++ Y G + +I G + E + Sbjct: 66 TWLGSQCRLHELREKERISVAAASKILSNLVYQYKGAG----LSMGTMICGYTRKEGPTI 121 Query: 150 FETDPSGALIEYKATAIGSGRPVVMELLEKEYRDDITLDEGLELAITALTKANEDIKPEN 209 + D G ++ +GSG+ +L+ Y+ D+++++ L L ++ A Sbjct: 122 YYVDSDGTRLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSG 181 Query: 210 VDVCIITVKDAQFKKIPVEEIKKLIEKVKKKLNEENK 246 V + V + + ++ +L KVK++ N Sbjct: 182 GSVNLYHVTEDGWIYHGNHDVGELFWKVKEEEGSFNN 218 >5LEZ-N nrPDB Length = 205 Score = 49.7 bits (117), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 42/170 (24%), Positives = 72/170 (42%), Gaps = 7/170 (4%) Query: 36 TTAIGIACKDGVVLAVDRRITS-KLVKIRSIEKIFQIDDHVAAATSGLVADARVLIDRAR 94 TT + + GVVL D R T+ + R +K+ I D + SG AD + + D Sbjct: 1 TTIMAVQFDGGVVLGADSRTTTGSYIANRVTDKLTPIHDRIFCCRSGSAADTQAVADAVT 60 Query: 95 LEAQIYRLTYGEEISIEMLAKKICDIKQAYTQHGGVRPFGVSLLIAGIDKNEARLFETDP 154 + + + E + A ++ Y + ++IAG D E + P Sbjct: 61 YQLGFHSIELNEPPLVHTAASLFKEMCYRYRED-----LMAGIIIAGWDPQEGGQVYSVP 115 Query: 155 SGALIEYKATAIG-SGRPVVMELLEKEYRDDITLDEGLELAITALTKANE 203 G ++ ++ AIG SG + ++ YR+ +T +E L+ AL A E Sbjct: 116 MGGMMVRQSFAIGGSGSSYIYGYVDATYREGMTKEECLQFTANALALAME 165 >5FMG-K nrPDB Length = 195 Score = 48.5 bits (114), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 40/161 (24%), Positives = 74/161 (45%), Gaps = 8/161 (4%) Query: 37 TAIGIACKDGVVLAVDRRITSKLVKIRSIE--KIFQIDDHVAAATSGLVADARVLIDRAR 94 T IG+ + VVLA D + ++K+++ + K + I + G + D + R Sbjct: 3 TLIGLRGNNFVVLAADTYSINSIIKLKNDDNTKFYDIHGNKCLLLGGSIGDRLQFGEFIR 62 Query: 95 LEAQIYRLTYGEEISIEMLAKKICDIKQAYTQHGGVR-PFGVSLLIAGIDKNEA-RLFET 152 +Y+ + + +M K + + R PF V+ LIAG DK + +L+ Sbjct: 63 KNVHLYQY----QNNTDMFVKSFAFFTRKNLAYYLRRNPFEVNCLIAGYDKKDGYQLYWC 118 Query: 153 DPSGALIEYKATAIGSGRPVVMELLEKEYRDDITLDEGLEL 193 D + A G G +V +L+K Y +++T+DE L++ Sbjct: 119 DYLSNMDSVNKGAHGYGAYLVSAILDKYYHENLTVDEALDI 159 >1Q5Q-H nrPDB Length = 235 Score = 47.8 bits (112), Expect = 5e-06, Method: Compositional matrix adjust. Identities = 51/177 (28%), Positives = 81/177 (45%), Gaps = 8/177 (4%) Query: 36 TTAIGIACKDGVVLAVDRRIT-SKLVKIRSIEKIFQIDDHVAAATSGLVADARVLIDRAR 94 TT + + K GV+LA DRR T L+ R +EK++ D++ AA +G A L+ Sbjct: 1 TTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAGTAGIAIELVRLFA 60 Query: 95 LEAQIYRLTYGEEISIEMLAKKICDIKQ----AYTQHGGVRPFGVSLLIAGIDKNEA-RL 149 +E + Y G ++ + A ++ + + A Q V P V + D++ A R+ Sbjct: 61 VELEHYEKIEGVPLTFDGKANRLASMVRGNLGAAMQGLAVVPLLVGYDLDADDESRAGRI 120 Query: 150 FETDPSGALIEYKAT--AIGSGRPVVMELLEKEYRDDITLDEGLELAITALTKANED 204 D G E +A A+GSG L+K Y D + L AI +L A +D Sbjct: 121 VSYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDSDEETALRAAIESLYDAADD 177 >1Q5R-H nrPDB Length = 294 Score = 47.4 bits (111), Expect = 6e-06, Method: Compositional matrix adjust. Identities = 51/179 (28%), Positives = 81/179 (45%), Gaps = 8/179 (4%) Query: 34 RGTTAIGIACKDGVVLAVDRRIT-SKLVKIRSIEKIFQIDDHVAAATSGLVADARVLIDR 92 GTT + + K GV+LA DRR T L+ R +E ++ D++ AA +G A L+ Sbjct: 64 HGTTIVALTYKGGVLLAGDRRATQGNLIASRDVEAVYVTDEYSAAGIAGTAGIAIELVRL 123 Query: 93 ARLEAQIYRLTYGEEISIEMLAKKICDIKQ----AYTQHGGVRPFGVSLLIAGIDKNEA- 147 +E + Y G ++ + A ++ + + A Q V P V + D++ A Sbjct: 124 FAVELEHYEKIEGVPLTFDGKANRLASMVRGNLGAAMQGLAVVPLLVGYDLDADDESRAG 183 Query: 148 RLFETDPSGALIEYKAT--AIGSGRPVVMELLEKEYRDDITLDEGLELAITALTKANED 204 R+ D G E +A A+GSG L+K Y D + L AI +L A +D Sbjct: 184 RIVSYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDSDEETALRAAIESLYDAADD 242 >5LF3-J nrPDB Length = 201 Score = 45.1 bits (105), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 42/161 (26%), Positives = 79/161 (49%), Gaps = 12/161 (7%) Query: 39 IGIACKDGVVLAVDRRITSKLVKIRS-IEKIFQIDDHVAAATSGLVADARVLIDRARLEA 97 IGI D V++A DR S +V+++ +K+F++ + + G D + + Sbjct: 5 IGIQGPDYVLVASDRVAASNIVQMKDDHDKMFKMSEKILLLCVGEAGDTVQFAEYIQKNV 64 Query: 98 QIYRLTYGEEISIEMLA----KKICDIKQAYTQHGGVRPFGVSLLIAGIDKNEA-RLFET 152 Q+Y++ G E+S A + + D ++ T P+ V+LL+AG D++E L+ Sbjct: 65 QLYKMRNGYELSPTAAANFTRRNLADCLRSRT------PYHVNLLLAGYDEHEGPALYYM 118 Query: 153 DPSGALIEYKATAIGSGRPVVMELLEKEYRDDITLDEGLEL 193 D AL + A G G + + +L++ Y I+ + +EL Sbjct: 119 DYLAALAKAPFAAHGYGAFLTLSILDRYYTPTISRERAVEL 159 >5LF6-M nrPDB Length = 219 Score = 43.5 bits (101), Expect = 8e-05, Method: Compositional matrix adjust. Identities = 37/154 (24%), Positives = 73/154 (47%), Gaps = 12/154 (7%) Query: 35 GTTAIGIACKDGVVLAVDRRIT-SKLVKIRSIEKIFQIDDHVAAATSGLVADARVL---I 90 GT+ +G+ + GVV+A D + L + R+I +I ++++ SG AD + L + Sbjct: 8 GTSVLGVKFEGGVVIAADMLGSYGSLARFRNISRIMRVNNSTMLGASGDYADFQYLKQVL 67 Query: 91 DRARLEAQIYRLTYGEEISIEMLAKKICDIKQAYTQHGGVRPFGVSLLIAGIDKNEARLF 150 + ++ ++ L G S + + + Y++ + P +++I G E+ L Sbjct: 68 GQMVIDEEL--LGDGHSYSPRAIHSWLT--RAMYSRRSKMNPLWNTMVIGGYADGESFLG 123 Query: 151 ETDPSGALIEYKATAIGSG----RPVVMELLEKE 180 D G E + A G G +P++ E+LEK+ Sbjct: 124 YVDMLGVAYEAPSLATGYGAYLAQPLLREVLEKQ 157 >5FMG-N nrPDB Length = 265 Score = 43.5 bits (101), Expect = 9e-05, Method: Compositional matrix adjust. Identities = 21/59 (35%), Positives = 36/59 (61%), Gaps = 1/59 (1%) Query: 32 VRRGTTAIGIACKDGVVLAVDRRIT-SKLVKIRSIEKIFQIDDHVAAATSGLVADARVL 89 V GT+ I I K G+++A DR+ + K +++E+IF+I++ SG +ADA+ L Sbjct: 6 VVTGTSVIAIKYKHGIMIAADRKASYGSYAKFQNVERIFKINNKTVMGFSGELADAQYL 64 >6EPE-7 nrPDB Length = 263 Score = 43.5 bits (101), Expect = 9e-05, Method: Compositional matrix adjust. Identities = 38/154 (24%), Positives = 71/154 (46%), Gaps = 12/154 (7%) Query: 35 GTTAIGIACKDGVVLAVDRRIT-SKLVKIRSIEKIFQIDDHVAAATSGLVADARVL---I 90 GT+ +G+ GVV+A D + L + R+I +I +++D SG AD + L + Sbjct: 52 GTSVLGVKFDCGVVIAADMLGSYGSLARFRNISRIMRVNDSTMLGASGDYADFQYLKQVL 111 Query: 91 DRARLEAQIYRLTYGEEISIEMLAKKICDIKQAYTQHGGVRPFGVSLLIAGIDKNEARLF 150 + ++ ++ +G+ S A + Y++ + P + +I G E+ L Sbjct: 112 GQMVIDEEL----FGDGHSYSPRAIHSWLTRAMYSRRSKMNPLWNTKVIGGYAGGESFLG 167 Query: 151 ETDPSGALIEYKATAIGSG----RPVVMELLEKE 180 D G E + A G G +P++ E+LEK+ Sbjct: 168 YVDMLGVAYEAPSLATGYGAYLAQPLLREVLEKQ 201 >5GJQ-g nrPDB Length = 264 Score = 43.5 bits (101), Expect = 9e-05, Method: Compositional matrix adjust. Identities = 37/154 (24%), Positives = 73/154 (47%), Gaps = 12/154 (7%) Query: 35 GTTAIGIACKDGVVLAVDRRIT-SKLVKIRSIEKIFQIDDHVAAATSGLVADARVL---I 90 GT+ +G+ + GVV+A D + L + R+I +I ++++ SG AD + L + Sbjct: 53 GTSVLGVKFEGGVVIAADMLGSYGSLARFRNISRIMRVNNSTMLGASGDYADFQYLKQVL 112 Query: 91 DRARLEAQIYRLTYGEEISIEMLAKKICDIKQAYTQHGGVRPFGVSLLIAGIDKNEARLF 150 + ++ ++ L G S + + + Y++ + P +++I G E+ L Sbjct: 113 GQMVIDEEL--LGDGHSYSPRAIHSWLT--RAMYSRRSKMNPLWNTMVIGGYADGESFLG 168 Query: 151 ETDPSGALIEYKATAIGSG----RPVVMELLEKE 180 D G E + A G G +P++ E+LEK+ Sbjct: 169 YVDMLGVAYEAPSLATGYGAYLAQPLLREVLEKQ 202 >5FMG-J nrPDB Length = 218 Score = 41.2 bits (95), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 26/111 (23%), Positives = 50/111 (45%), Gaps = 6/111 (5%) Query: 34 RGTTAIGIACKDGVVLAVDRRITSKLVKIRS--IEKIFQIDDHVAAATSGLVADARVLID 91 G +G++ + V +A D R+ + S KIF+++++V SGL D + L + Sbjct: 8 NGGCVLGMSGSNCVAIACDLRLGANTFTTVSTKFSKIFKMNNNVYVGLSGLATDIQTLYE 67 Query: 92 RARLEAQIYRLTYGEEISIEMLAKKICDIKQAYTQHGGVRPFGVSLLIAGI 142 R +Y + E+ +E A + I Y+ P+ V+ ++ G Sbjct: 68 ILRYRVNLYEVRQDAEMDVECFANMLSSI--LYSNR--FSPYFVNPIVVGF 114 >2JAY-A nrPDB Length = 291 Score = 41.2 bits (95), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 52/182 (28%), Positives = 77/182 (42%), Gaps = 14/182 (7%) Query: 34 RGTTAIGIACKDGVVLAVDRRIT-SKLVKIRSIEKIFQIDDHVAAATSGLVADARVLIDR 92 GTT + + GVV+A DRR T ++ R + K++ DD+ A +G+ A V ++ Sbjct: 56 HGTTIVALKYPGGVVMAGDRRSTQGNMISGRDVRKVYITDDYTA---TGIAGTAAVAVEF 112 Query: 93 ARL---EAQIYRLTYGEEIS----IEMLAKKICDIKQAYTQHGGVRPFGVSLLIAGIDKN 145 ARL E + Y G ++ I LA + A Q P I D Sbjct: 113 ARLYAVELEHYEKLEGVPLTFAGKINRLAIMVRGNLAAAMQGLLALPLLAGYDIHASDPQ 172 Query: 146 EA-RLFETDPSGALI--EYKATAIGSGRPVVMELLEKEYRDDITLDEGLELAITALTKAN 202 A R+ D +G E A+GSG ++K Y D GL +A+ AL A Sbjct: 173 SAGRIVSFDAAGGWNIEEEGYQAVGSGSLFAKSSMKKLYSQVTDGDSGLRVAVEALYDAA 232 Query: 203 ED 204 +D Sbjct: 233 DD 234 >3UNF-N nrPDB Length = 199 Score = 40.8 bits (94), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 48/204 (23%), Positives = 85/204 (41%), Gaps = 8/204 (3%) Query: 36 TTAIGIACKDGVVLAVDRRITSKLVKI-RSIEKIFQIDDHVAAATSGLVADARVLIDRAR 94 TT + + GVV+ D R+++ + R +K+ + + A SG ADA+ + D A Sbjct: 1 TTIMAVEFDGGVVVGSDSRVSAGTAVVNRVFDKLSPLHQRIFCALSGSAADAQAIADMAA 60 Query: 95 LEAQIYRLTYGEEISIEMLAKKICDIKQAYTQHGGVRPFGVSLLIAGIDKNEARLFETDP 154 + +++ L E + A + +I Y + L++AG D+ E Sbjct: 61 YQLELHGLELEEPPLVLAAANVVKNISYKYRED-----LLAHLIVAGWDQREGGQVYGTM 115 Query: 155 SGALIEYKATAIGSGRPVVMELLEKEYRDDITLDEGLELAITALTKA-NEDIKPENVDVC 213 G LI T GSG + ++ Y+ +T +E A+T A N D V Sbjct: 116 GGMLIRQPFTIGGSGSSYIYGYVDAAYKPGMTPEECRRFTTNAITLAMNRDGSSGGVIYL 175 Query: 214 I-ITVKDAQFKKIPVEEIKKLIEK 236 + IT + I +E+ K ++ Sbjct: 176 VTITAAGVDHRVILGDELPKFYDE 199 >4Y8P-I nrPDB Length = 205 Score = 40.4 bits (93), Expect = 7e-04, Method: Compositional matrix adjust. Identities = 31/118 (26%), Positives = 52/118 (44%), Gaps = 6/118 (5%) Query: 34 RGTTAIGIACKDGVVLAVDRRITSKLVKIRS-IEKIFQIDDHVAAATSGLVADARVLIDR 92 G + + KD V +A D R+ S+ + + + EKIF HV +GL D L + Sbjct: 8 NGGIVVAMTGKDCVAIACDLRLGSQSLGVSNKFEKIFHYG-HVFLGITGLATDVTTLNEM 66 Query: 93 ARLEAQIYRLTYGEEISIEMLAKKICDIKQAYTQHGGVRPFGVSLLIAGIDKNEARLF 150 R + +Y+L I E + + Y + G P+ V ++AGI+ + F Sbjct: 67 FRYKTNLYKLKEERAIEPETFTQLVS--SSLYERRFG--PYFVGPVVAGINSKSGKPF 120 >3UNE-I nrPDB Length = 205 Score = 40.0 bits (92), Expect = 0.001, Method: Compositional matrix adjust. Identities = 30/119 (25%), Positives = 54/119 (45%), Gaps = 7/119 (5%) Query: 34 RGTTAIGIACKDGVVLAVDRR--ITSKLVKIRSIEKIFQIDDHVAAATSGLVADARVLID 91 G + + K+ V +A DRR I +++V +KIF + D + +GL D + + Sbjct: 7 NGGAVMAMKGKNCVAIAADRRFGIQAQMVT-TDFQKIFPMGDRLYIGLAGLATDVQTVAQ 65 Query: 92 RARLEAQIYRLTYGEEISIEMLAKKICDIKQAYTQHGGVRPFGVSLLIAGIDKNEARLF 150 R + +Y L G +I L + ++ Y + G P+ +IAG+D + F Sbjct: 66 RLKFRLNLYELKEGRQIKPYTLMSMVANL--LYEKRFG--PYYTEPVIAGLDPKTFKPF 120 >6AVO-A nrPDB Length = 199 Score = 39.3 bits (90), Expect = 0.002, Method: Compositional matrix adjust. Identities = 34/155 (21%), Positives = 67/155 (43%), Gaps = 6/155 (3%) Query: 36 TTAIGIACKDGVVLAVDRRITS-KLVKIRSIEKIFQIDDHVAAATSGLVADARVLIDRAR 94 TT + + GVV+ D R+++ + V R +K+ + + + A SG ADA+ + D A Sbjct: 1 TTIMAVEFDGGVVMGSDSRVSAGEAVVNRVFDKLSPLHERIYCALSGSAADAQAVADMAA 60 Query: 95 LEAQIYRLTYGEEISIEMLAKKICDIKQAYTQHGGVRPFGVSLLIAGIDKNEARLFETDP 154 + +++ + E + A + +I Y + L++AG D+ E Sbjct: 61 YQLELHGIELEEPPLVLAAANVVRNISYKYRED-----LSAHLMVAGWDQREGGQVYGTL 115 Query: 155 SGALIEYKATAIGSGRPVVMELLEKEYRDDITLDE 189 G L GSG + ++ Y+ ++ +E Sbjct: 116 GGMLTRQPFAIGGSGSTFIYGYVDAAYKPGMSPEE 150 >5LZP-A nrPDB Length = 242 Score = 37.4 bits (85), Expect = 0.006, Method: Compositional matrix adjust. Identities = 51/181 (28%), Positives = 77/181 (42%), Gaps = 18/181 (9%) Query: 37 TAIGIACKDGVVLAVDRRIT-SKLVKIRSIEKIFQIDDHVAAATSGLVADARVLIDRARL 95 T + + GVV+A DRR T ++ R + K++ DD+ A +G+ A V ++ ARL Sbjct: 2 TIVALKYPGGVVMAGDRRSTQGNMISGRDVRKVYITDDYTA---TGIAGTAAVAVEFARL 58 Query: 96 ---EAQIYR------LTYGEEISIEMLAKKICDIKQAYTQHGGVRPFGVSLLIAGIDKNE 146 E + Y LT+ +I+ LA + A Q P I D Sbjct: 59 YAVELEHYEKLEGVPLTFAGKIN--RLAIMVRGNLAAAMQGLLALPLLAGYDIHASDPQS 116 Query: 147 A-RLFETDPSGALI--EYKATAIGSGRPVVMELLEKEYRDDITLDEGLELAITALTKANE 203 A R+ D +G E A+GSG ++K Y D GL +A+ AL A + Sbjct: 117 AGRIVSFDAAGGWNIEEEGYQAVGSGSLFAKSSMKKLYSQVTDGDSGLRVAVEALYDAAD 176 Query: 204 D 204 D Sbjct: 177 D 177 >5FMG-H nrPDB Length = 252 Score = 37.4 bits (85), Expect = 0.007, Method: Compositional matrix adjust. Identities = 51/220 (23%), Positives = 88/220 (40%), Gaps = 57/220 (25%) Query: 36 TTAIGIACKDGVVLAVDRRITS-KLVKIRSIEKIFQIDDHVAAATSGLVADARVLID--- 91 TT IGI +GV+LA D R +S + + KI +I++++ SG A ++ +I+ Sbjct: 1 TTIIGIIYDNGVMLACDSRTSSGTFISNKCSRKINRINENLYVCRSGASAHSQKIIEIIK 60 Query: 92 ------------RARLE--AQIY-RLTYGEEISIEM------------------------ 112 + R IY TY EEI I+ Sbjct: 61 HYCVSMKNENRKKGRFHEGETIYDETTYDEEIDIDSINYLDYNNNNDNNLVTKNKYFYED 120 Query: 113 -------LAKKICDI--KQAYTQHGGVRPFGVSLLIAGIDK-NEARLFETDPSGALIEYK 162 L + + I K YT + + +L+ G DK + +L+ + +G++IE Sbjct: 121 KFNDYNPLVENVAHITKKIIYTNNNFL---SCALIFGGYDKIKKQQLYAVNLNGSIIEKH 177 Query: 163 ATAI-GSGRPVVMELLEKEYRDDITLDEGLELAITALTKA 201 A+ GSG + L+ +Y+ +T E L + + A Sbjct: 178 DFAVSGSGSIYIQSYLQDKYKKFMTKKECFNLILNCVKYA 217 >6A94-A nrPDB Length = 376 Score = 31.6 bits (70), Expect = 0.40, Method: Compositional matrix adjust. Identities = 35/123 (28%), Positives = 53/123 (43%), Gaps = 13/123 (10%) Query: 70 QIDDHVAAATSGLVADARVLIDRARLEAQIYRLTYGEEISIEMLAKKICDIKQAYTQHGG 129 QIDD + A G V +A+ ++ + Y YG+ IS E A K+ I + Sbjct: 250 QIDDALKLANEGKVKEAQAAAEQLKTTINAYIQKYGQSISNEQKACKVLGI-VFFLFVVM 308 Query: 130 VRPFGVSLLIAGIDKNEARLFETDPSGAL------IEYKATAIGSGRPVVMELLEKEYRD 183 PF ++ ++A I K D GAL I Y ++A+ P+V L K YR Sbjct: 309 WCPFFITNIMAVICKESC---NEDVIGALLNVFVWIGYLSSAV---NPLVYTLFNKTYRS 362 Query: 184 DIT 186 + Sbjct: 363 AFS 365 >6DTT-A nrPDB Length = 383 Score = 31.2 bits (69), Expect = 0.42, Method: Compositional matrix adjust. Identities = 14/24 (58%), Positives = 16/24 (66%) Query: 9 YDRAITVFSPEGRLYQVEYAREAV 32 YD A+ FS G+LY V YA EAV Sbjct: 88 YDTALKAFSYGGKLYGVPYAMEAV 111 >3JB9-S nrPDB Length = 488 Score = 29.6 bits (65), Expect = 1.4, Method: Compositional matrix adjust. Identities = 33/131 (25%), Positives = 56/131 (42%), Gaps = 11/131 (8%) Query: 75 VAAATSGLVADARVLIDRARLEAQIYRLTYGEEISIEMLAKKICDIKQAYTQH---GGVR 131 V TS + D +V +A + E+ I L ++ +I A QH V Sbjct: 285 VGEPTSSIPIDEKVNFLQAHPSGEYLLAASNEKCYIFSLKSQVYNITVA--QHITSLAVH 342 Query: 132 PFGVSLLIAGIDKNEARLFETDPSGALIEYKATAIGSGRPV-VMELLEKEYRDDITLDEG 190 P G +L +AG++ E R FET L ++ + PV ++ E Y +T ++ Sbjct: 343 PDG-NLFVAGLENGELRFFETSSGNELTKFGPHS----SPVKTLQFGENGYWLVVTTNDD 397 Query: 191 LELAITALTKA 201 ++ I L K+ Sbjct: 398 SDIFIWDLRKS 408 >4HO7-A nrPDB Length = 179 Score = 29.3 bits (64), Expect = 1.7, Method: Compositional matrix adjust. Identities = 37/139 (26%), Positives = 63/139 (45%), Gaps = 18/139 (12%) Query: 36 TTAIGIACKDGVVLAVDRRIT--SKLVKIRSIEKIFQIDDHVAAATSGLVADARVLIDRA 93 TT + + D VVL DR++T ++V S K+ +I+D V +G ADA L++ Sbjct: 1 TTILSVRKGDTVVLLGDRQVTLGERIVAKSSACKLRRINDDVVIGFAGSTADAISLME-- 58 Query: 94 RLEAQIYRLTYGEEISIEMLAKKICDIKQAYTQHGGVRPFGVSLLIAGIDKNEARLFETD 153 +LE +I L + ++ + + +R SL++ ++ E D Sbjct: 59 KLENKIGEFP-------NQLTRAAVELAKEWRTDRALRRLEASLIVCSAEET----LEID 107 Query: 154 PSGALIEYKA---TAIGSG 169 G +I +A AIGSG Sbjct: 108 GQGNVITPEADGIVAIGSG 126 >5HH9-A nrPDB Length = 390 Score = 29.3 bits (64), Expect = 1.9, Method: Compositional matrix adjust. Identities = 12/49 (24%), Positives = 28/49 (57%) Query: 198 LTKANEDIKPENVDVCIITVKDAQFKKIPVEEIKKLIEKVKKKLNEENK 246 L+ I+P+ + + V+ K+P+ EI KL+ ++ +K +E+++ Sbjct: 147 LSSIAAQIRPQTRVLGMTWVQSGSGVKLPIREIGKLVRELNQKRDEQDR 195 >1HBX-G nrPDB Length = 157 Score = 28.9 bits (63), Expect = 2.6, Method: Compositional matrix adjust. Identities = 15/39 (38%), Positives = 21/39 (53%), Gaps = 2/39 (5%) Query: 206 KPENVDVCIITVKDAQFKKIPVEEIKKL--IEKVKKKLN 242 KP+N + T D QFK + EE+ +L I K K +N Sbjct: 18 KPQNKHMICWTSNDGQFKLLQAEEVARLWGIRKNKPNMN 56 >2GHB-A nrPDB Length = 382 Score = 28.5 bits (62), Expect = 2.7, Method: Compositional matrix adjust. Identities = 11/24 (45%), Positives = 16/24 (66%) Query: 9 YDRAITVFSPEGRLYQVEYAREAV 32 Y+ A+ FS G+LY + YA EA+ Sbjct: 88 YETALNAFSYGGKLYGIPYAMEAI 111 >3IEF-A nrPDB Length = 233 Score = 28.5 bits (62), Expect = 2.9, Method: Compositional matrix adjust. Identities = 25/77 (32%), Positives = 38/77 (49%), Gaps = 12/77 (15%) Query: 15 VFSPEGRLYQVEYAREAVRRGTTAIGIACKDGVVLAVDRRITSKLVKIRSIEKIFQIDDH 74 + SP GRL YAR R ++ + + C G VD RI ++ R +E++ I D+ Sbjct: 85 LMSPRGRLLNQAYARSLAR--SSGVTLVC--GRFEGVDERI----IEARELEEV-SIGDY 135 Query: 75 VAAATSGLVADARVLID 91 + SG A VL+D Sbjct: 136 I---LSGGETAALVLLD 149 >5K8K-A nrPDB Length = 256 Score = 28.1 bits (61), Expect = 3.8, Method: Compositional matrix adjust. Identities = 15/34 (44%), Positives = 22/34 (64%), Gaps = 1/34 (2%) Query: 114 AKKICDIKQAYTQHGGVRPFGVSLLIAGIDKNEA 147 +++I D+ QA+T V+ FGV+LLI G EA Sbjct: 169 SQEIMDVNQAFTAEK-VQEFGVNLLIHGHTHREA 201 >4NLE-A nrPDB Length = 488 Score = 27.7 bits (60), Expect = 4.7, Method: Compositional matrix adjust. Identities = 14/41 (34%), Positives = 21/41 (51%) Query: 8 AYDRAITVFSPEGRLYQVEYAREAVRRGTTAIGIACKDGVV 48 A D + ++SPE ++ AV R +G+A DGVV Sbjct: 28 ASDEMVAIWSPEAKIIAERRLWLAVLRAQAELGVAVPDGVV 68 >3MOP-A nrPDB Length = 110 Score = 27.7 bits (60), Expect = 5.6, Method: Compositional matrix adjust. Identities = 18/47 (38%), Positives = 26/47 (55%), Gaps = 2/47 (4%) Query: 146 EARLFET--DPSGALIEYKATAIGSGRPVVMELLEKEYRDDITLDEG 190 E R ET DP+G L++ G+ ++ELL K RDD+ L+ G Sbjct: 42 EIRQLETQADPTGRLLDAWQGRPGASVGRLLELLTKLGRDDVLLELG 88 >1BC8-C nrPDB Length = 93 Score = 27.3 bits (59), Expect = 6.2, Method: Compositional matrix adjust. Identities = 15/41 (36%), Positives = 22/41 (53%), Gaps = 2/41 (4%) Query: 206 KPENVDVCIITVKDAQFKKIPVEEIKKL--IEKVKKKLNEE 244 KP+N + T D QFK + EE+ +L I K K +N + Sbjct: 17 KPQNKHMICWTSNDGQFKLLQAEEVARLWGIRKNKPNMNYD 57 >6A4U-A nrPDB Length = 169 Score = 27.3 bits (59), Expect = 7.0, Method: Compositional matrix adjust. Identities = 18/54 (33%), Positives = 28/54 (51%), Gaps = 8/54 (14%) Query: 130 VRPFGVSL--LIAGIDKNEARLFETDPSGALIEYKATAIGSGRPVVMELLEKEY 181 +R +G L L A +D E + +L+E +TA G+ P + +LLE EY Sbjct: 86 MREWGTGLEALQAALD------LEKQVNQSLLELHSTASGNNDPHLTKLLEDEY 133 >3M1C-A nrPDB Length = 762 Score = 26.9 bits (58), Expect = 9.6, Method: Compositional matrix adjust. Identities = 18/80 (22%), Positives = 30/80 (37%), Gaps = 9/80 (11%) Query: 29 REAVRRGTTAIGIACKDGVVLAVDRRITSKLVKIRSIEKIFQIDDHVAA---------AT 79 RE RRG C V A + + L + + +F + DH + A Sbjct: 493 RERARRGLLITTALCTSDVAAATHADLRAALARTDHQKNLFWLPDHFSPCAASLRFDLAE 552 Query: 80 SGLVADARVLIDRARLEAQI 99 G + DA + R+ + A + Sbjct: 553 GGFILDALAMATRSDIPADV 572 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 3H4P-A nrPDB 356 7e-99 6HE5-A nrPDB 291 2e-79 5FMG-E nrPDB 265 2e-71 5T0I-L nrPDB 263 5e-71 5FMG-D nrPDB 258 2e-69 4YA5-C nrPDB 253 7e-68 2Z5C-C nrPDB 252 9e-68 1IRU-A nrPDB 252 1e-67 2KU2-A nrPDB 251 4e-67 5LEZ-C nrPDB 250 4e-67 5LF0-A nrPDB 249 8e-67 1G0U-D nrPDB 249 1e-66 5GJR-F nrPDB 249 1e-66 6FVW-g nrPDB 247 4e-66 5FGG-F nrPDB 246 7e-66 5LE5-B nrPDB 244 3e-65 5FMG-C nrPDB 240 3e-64 5FMG-B nrPDB 240 3e-64 4FZC-A nrPDB 235 2e-62 6J30-C nrPDB 233 7e-62 5FMG-F nrPDB 229 8e-61 3NZW-E nrPDB 219 9e-58 5L5A-K nrPDB 219 1e-57 6EPD-G nrPDB 217 5e-57 5FMG-A nrPDB 215 1e-56 5L64-K nrPDB 214 2e-56 3NZW-K nrPDB 212 9e-56 6EPF-5 nrPDB 207 3e-54 5CZ8-K nrPDB 207 4e-54 6AVO-C nrPDB 205 1e-53 5L5W-G nrPDB 202 1e-52 3UNF-K nrPDB 202 1e-52 5LN3-5 nrPDB 200 4e-52 5FMG-G nrPDB 200 6e-52 3UNB-K nrPDB 194 5e-50 3IPM-H nrPDB 188 2e-48 3H4P-a nrPDB 188 2e-48 6HEC-1 nrPDB 188 2e-48 6EPF-2 nrPDB 186 9e-48 3UNH-H nrPDB 185 2e-47 6AVO-B nrPDB 184 3e-47 5FGI-H nrPDB 183 8e-47 5FMG-I nrPDB 183 9e-47 6EPC-1 nrPDB 182 1e-46 5GJQ-a nrPDB 181 3e-46 5L4G-8 nrPDB 181 3e-46 6HV7-H nrPDB 175 2e-44 6HUB-H nrPDB 174 3e-44 5FMG-L nrPDB 174 3e-44 5LEZ-N nrPDB 165 1e-41 6AVO-A nrPDB 160 5e-40 3UNF-N nrPDB 154 4e-38 5MPC-h nrPDB 148 1e-36 5FMG-M nrPDB 144 4e-35 5FGE-J nrPDB 138 2e-33 3WXR-K nrPDB 137 3e-33 1Q5R-H nrPDB 137 5e-33 1Q5Q-H nrPDB 133 5e-32 5FMG-K nrPDB 131 2e-31 2JAY-A nrPDB 125 2e-29 3NZW-L nrPDB 125 2e-29 5LF3-J nrPDB 123 6e-29 3UNE-I nrPDB 121 3e-28 6EPE-7 nrPDB 120 6e-28 4Y8P-I nrPDB 120 7e-28 5GJQ-g nrPDB 120 8e-28 5LF6-M nrPDB 118 2e-27 5FMG-J nrPDB 106 7e-24 5FMG-N nrPDB 102 2e-22 Sequences not found previously or not previously below threshold: 5L4G-U nrPDB 117 4e-27 5LZP-A nrPDB 117 6e-27 5VFT-S nrPDB 116 6e-27 6EPF-6 nrPDB 115 2e-26 6GOP-M nrPDB 94 7e-20 5FMG-H nrPDB 91 5e-19 4HO7-A nrPDB 60 8e-10 5LOY-A nrPDB 59 2e-09 5LOX-A nrPDB 55 5e-08 2FHG-A nrPDB 54 6e-08 5NYW-A nrPDB 51 7e-07 5JI2-A nrPDB 50 7e-07 5NYF-A nrPDB 48 3e-06 1OFH-G nrPDB 44 7e-05 1M4Y-A nrPDB 41 7e-04 2Z3B-A nrPDB 38 0.006 3TY6-A nrPDB 36 0.011 6DTT-A nrPDB 33 0.16 2E21-A nrPDB 31 0.38 3H8L-A nrPDB 31 0.60 5B46-A nrPDB 30 0.94 2V3B-A nrPDB 30 1.2 2GHB-A nrPDB 30 1.4 1VRD-A nrPDB 30 1.5 3WNB-A nrPDB 29 1.8 1JSO-A nrPDB 29 1.9 3T51-B nrPDB 29 2.2 3OPO-A nrPDB 29 2.3 2WRH-H nrPDB 29 2.3 1G61-A nrPDB 29 2.9 1RFZ-A nrPDB 28 3.2 5UDI-A nrPDB 28 5.0 5A5T-C nrPDB 28 5.3 >3H4P-A nrPDB Length = 264 Score = 356 bits (913), Expect = 7e-99, Method: Composition-based stats. Identities = 261/261 (100%), Positives = 261/261 (100%) Query: 1 MQMVPPSAYDRAITVFSPEGRLYQVEYAREAVRRGTTAIGIACKDGVVLAVDRRITSKLV 60 MQMVPPSAYDRAITVFSPEGRLYQVEYAREAVRRGTTAIGIACKDGVVLAVDRRITSKLV Sbjct: 4 MQMVPPSAYDRAITVFSPEGRLYQVEYAREAVRRGTTAIGIACKDGVVLAVDRRITSKLV 63 Query: 61 KIRSIEKIFQIDDHVAAATSGLVADARVLIDRARLEAQIYRLTYGEEISIEMLAKKICDI 120 KIRSIEKIFQIDDHVAAATSGLVADARVLIDRARLEAQIYRLTYGEEISIEMLAKKICDI Sbjct: 64 KIRSIEKIFQIDDHVAAATSGLVADARVLIDRARLEAQIYRLTYGEEISIEMLAKKICDI 123 Query: 121 KQAYTQHGGVRPFGVSLLIAGIDKNEARLFETDPSGALIEYKATAIGSGRPVVMELLEKE 180 KQAYTQHGGVRPFGVSLLIAGIDKNEARLFETDPSGALIEYKATAIGSGRPVVMELLEKE Sbjct: 124 KQAYTQHGGVRPFGVSLLIAGIDKNEARLFETDPSGALIEYKATAIGSGRPVVMELLEKE 183 Query: 181 YRDDITLDEGLELAITALTKANEDIKPENVDVCIITVKDAQFKKIPVEEIKKLIEKVKKK 240 YRDDITLDEGLELAITALTKANEDIKPENVDVCIITVKDAQFKKIPVEEIKKLIEKVKKK Sbjct: 184 YRDDITLDEGLELAITALTKANEDIKPENVDVCIITVKDAQFKKIPVEEIKKLIEKVKKK 243 Query: 241 LNEENKKEEENREETKEKQEE 261 LNEENKKEEENREETKEKQEE Sbjct: 244 LNEENKKEEENREETKEKQEE 264 >6HE5-A nrPDB Length = 247 Score = 291 bits (746), Expect = 2e-79, Method: Composition-based stats. Identities = 150/248 (60%), Positives = 195/248 (78%), Gaps = 2/248 (0%) Query: 1 MQMVPPSAYDRAITVFSPEGRLYQVEYAREAVRRGTTAIGIACKDGVVLAVDRRITSKLV 60 M +P YDRAITVFSP+GRL+QVEYAREAV+RG TAIGI CK+GV+L D+R+ SKL+ Sbjct: 1 MGHLPQMGYDRAITVFSPDGRLFQVEYAREAVKRGATAIGIKCKEGVILIADKRVGSKLL 60 Query: 61 KIRSIEKIFQIDDHVAAATSGLVADARVLIDRARLEAQIYRLTYGEEISIEMLAKKICDI 120 + +IEKI++ID+H+ AATSGLVADARVLIDRAR+EAQI RLTY E I+++ LAKKICD Sbjct: 61 EADTIEKIYKIDEHICAATSGLVADARVLIDRARIEAQINRLTYDEPITVKELAKKICDF 120 Query: 121 KQAYTQHGGVRPFGVSLLIAGIDKNEARLFETDPSGALIEYKATAIGSGRPVVMELLEKE 180 KQ YTQ+GGVRPFGVSLLIAG+D+ +L+ETDPSGAL+EYKATAIG GR V E EKE Sbjct: 121 KQQYTQYGGVRPFGVSLLIAGVDEV-PKLYETDPSGALLEYKATAIGMGRNAVTEFFEKE 179 Query: 181 YRDDITLDEGLELAITALTKANE-DIKPENVDVCIITVKDAQFKKIPVEEIKKLIEKVKK 239 YRDD++ D+ + L + A+ + E ++ PEN++V + V D FK++ EE+K +E+ + Sbjct: 180 YRDDLSFDDAMVLGLVAMGLSIESELVPENIEVGYVKVDDRTFKEVSPEELKPYVERANE 239 Query: 240 KLNEENKK 247 ++ E KK Sbjct: 240 RIRELLKK 247 >5FMG-E nrPDB Length = 256 Score = 265 bits (677), Expect = 2e-71, Method: Composition-based stats. Identities = 100/237 (42%), Positives = 147/237 (62%), Gaps = 8/237 (3%) Query: 7 SAYDRAITVFSPEGRLYQVEYAREAVRRGTTAIGIACKDGVVLAVDRRITSKLVKIRSIE 66 S YDR + FSPEGRL+QVEYA A++ G+TA+GI DGV+LA +RRI+S L++ S+E Sbjct: 6 SEYDRGVNTFSPEGRLFQVEYALGAIKLGSTAVGICVNDGVILASERRISSTLIEKDSVE 65 Query: 67 KIFQIDDHVAAATSGLVADARVLIDRARLEAQIYRLTYGEEISIEMLAKKICDIKQAYTQ 126 K+ IDDH+ A SGL+ADAR LID AR+E Y+ Y E I+I+ + I ++ ++ Sbjct: 66 KLLSIDDHIGCAMSGLMADARTLIDYARVECNHYKFIYNENINIKSCVELISELALDFSN 125 Query: 127 HGG-------VRPFGVSLLIAGIDKNEARLFETDPSGALIEYKATAIGSGRPVVMELLEK 179 RPFGV+LLI G+DKN L+ T+PSG + A +IGS + LL++ Sbjct: 126 LSDSKRKKIMSRPFGVALLIGGVDKNGPCLWYTEPSGTNTRFSAASIGSAQEGAELLLQE 185 Query: 180 EYRDDITLDEGLELAITALTKANED-IKPENVDVCIITVKDAQFKKIPVEEIKKLIE 235 Y+ D+T ++ LA+T L + ED + NV++C I D F K ++I ++I+ Sbjct: 186 NYKKDMTFEQAEILALTVLRQVMEDKLSTSNVEICAIKKSDQTFYKYNTDDISRIID 242 >5T0I-L nrPDB Length = 268 Score = 263 bits (673), Expect = 5e-71, Method: Composition-based stats. Identities = 79/258 (30%), Positives = 138/258 (53%), Gaps = 9/258 (3%) Query: 9 YDRAITVFSPEGRLYQVEYAREAVRRGTTAIGIACKDGVVLAVDRRITSKLVKIRSIEKI 68 YD +TV+SP+GR++Q+EYA EAV++G+ +G+ K VL +R S+L + +KI Sbjct: 11 YDNDVTVWSPQGRIHQIEYAMEAVKQGSATVGLKSKTHAVLVALKRAQSELAAHQ--KKI 68 Query: 69 FQIDDHVAAATSGLVADARVLIDRARLEAQIYRLTYGEEISIEMLAKKICDIKQAYTQHG 128 +D+H+ + +GL ADAR+L + R E R + + + L I Q TQ Sbjct: 69 LHVDNHIGISIAGLTADARLLCNFMRQECLDSRFVFDRPLPVSRLVSLIGSKTQIPTQRY 128 Query: 129 GVRPFGVSLLIAGIDKNEARLFETDPSGALIEYKATAIGSGRPVVMELLEKEYRD--DIT 186 G RP+GV LLIAG D +F+T PS + +A +IG+ LE+ + + Sbjct: 129 GRRPYGVGLLIAGYDDMGPHIFQTCPSANYFDCRAMSIGARSQSARTYLERHMSEFMECN 188 Query: 187 LDEGLELAITALTK---ANEDIKPENVDVCIITVKDAQFKKIPVEEIKKLIEKVKKKLNE 243 L+E ++ + AL + A +D+ +NV + I+ KD +F +++ +E ++++ + Sbjct: 189 LNELVKHGLRALRETLPAEQDLTTKNVSIGIVG-KDLEFTIYDDDDVSPFLEGLEER-PQ 246 Query: 244 ENKKEEENREETKEKQEE 261 + + +E EK +E Sbjct: 247 RKAQPAQPADEPAEKADE 264 >5FMG-D nrPDB Length = 241 Score = 258 bits (659), Expect = 2e-69, Method: Composition-based stats. Identities = 96/244 (39%), Positives = 155/244 (63%), Gaps = 4/244 (1%) Query: 7 SAYDRAITVFSPEGRLYQVEYAREAVRRGTTAIGIACKDGVVLAVDRRITSKLVKIRSIE 66 +YDRAITVFSP+G L QVE+A EAV++G A+ I + VLAV+++ KL ++ E Sbjct: 1 MSYDRAITVFSPDGHLLQVEHALEAVKKGGCAVAIKSSNFAVLAVEKKNIPKLQNPKTTE 60 Query: 67 KIFQIDDHVAAATSGLVADARVLIDRARLEAQIYRLTYGEEISIEMLAKKICDIKQAYTQ 126 K+ ++D+H A +GL ADARVL+++ RLE Q Y L E ++ +AK + ++Q +T Sbjct: 61 KLIKLDEHNCLAFAGLNADARVLVNKTRLECQRYYLNMDEPAPVDYIAKYVAKVQQKFTH 120 Query: 127 HGGVRPFGVSLLIAGI-DKNEARLFETDPSGALIEYKATAIGSGRPVVMELLEKEYRDDI 185 GGVRPFG++ LIAG + E +++T+PSG +KA AIG +V E LEK Y++++ Sbjct: 121 RGGVRPFGIATLIAGFKNNKEICIYQTEPSGIYAAWKAQAIGKNAKIVQEFLEKNYQENM 180 Query: 186 TLDEGLELAITALTKANEDIKPENVDVCIITVKDAQFKKIPVEEIKKLIEKVKKKLNEEN 245 + + LA+ A+ + E + +NV+V ++T KD F I +EI ++E + ++ + N Sbjct: 181 EQKDCIFLALKAIFEVVE-LSSKNVEVALLTEKDLTF--IEEQEINSMVELIDQERTKNN 237 Query: 246 KKEE 249 ++ E Sbjct: 238 EQNE 241 >4YA5-C nrPDB Length = 254 Score = 253 bits (646), Expect = 7e-68, Method: Composition-based stats. Identities = 97/237 (40%), Positives = 152/237 (64%), Gaps = 8/237 (3%) Query: 7 SAYDRAITVFSPEGRLYQVEYAREAVRRGTTAIGIACKDGVVLAVDRRITSKLVKIR-SI 65 S YDRA+++FSP+G ++QVEYA EAV+RGT A+G+ K+ VVL +RR T KL R + Sbjct: 2 SGYDRALSIFSPDGHIFQVEYALEAVKRGTCAVGVKGKNCVVLGCERRSTLKLQDTRITP 61 Query: 66 EKIFQIDDHVAAATSGLVADARVLIDRARLEAQIYRLTYGEEISIEMLAKKICDIKQAYT 125 K+ +ID HV + SGL AD+R+LI++AR+EAQ +RLT + +++E L + + ++Q YT Sbjct: 62 SKVSKIDSHVVLSFSGLNADSRILIEKARVEAQSHRLTLEDPVTVEYLTRYVAGVQQRYT 121 Query: 126 QHGGVRPFGVSLLIAGIDK--NEARLFETDPSGALIEYKATAIGSGRPVVMELLEKEY-- 181 Q GGVRPFGVS LIAG D +E +L++T+PSG + A IG V E LEK Y Sbjct: 122 QSGGVRPFGVSTLIAGFDPRDDEPKLYQTEPSGIYSSWSAQTIGRNSKTVREFLEKNYDR 181 Query: 182 -RDDITLDEGLELAITALTKANEDIKPENVDVCIITVKDAQFKKIPVEEIKKLIEKV 237 T++E ++L + +L + + +N+++ ++ D+ + EEI + + ++ Sbjct: 182 KEPPATVEECVKLTVRSLLEVVQTG-AKNIEITVV-KPDSDIVALSSEEINQYVTQI 236 >2Z5C-C nrPDB Length = 262 Score = 252 bits (645), Expect = 9e-68, Method: Composition-based stats. Identities = 106/255 (41%), Positives = 153/255 (60%), Gaps = 9/255 (3%) Query: 4 VPPSAYDRAITVFSPEGRLYQVEYAREAVRRGTTAIGIACKDGVVLAVDRRITSKLVKIR 63 + S YDR ++ FSPEGRL+QVEY+ EA++ G+TAIGIA K+GVVL V++R TS L++ Sbjct: 5 LTRSEYDRGVSTFSPEGRLFQVEYSLEAIKLGSTAIGIATKEGVVLGVEKRATSPLLESD 64 Query: 64 SIEKIFQIDDHVAAATSGLVADARVLIDRARLEAQIYRLTYGEEISIEMLAKKICDIKQA 123 SIEKI +ID H+ A SGL ADAR +I+ AR A + L Y E+I++E L + +CD+ Sbjct: 65 SIEKIVEIDRHIGCAMSGLTADARSMIEHARTAAVTHNLYYDEDINVESLTQSVCDLALR 124 Query: 124 Y------TQHGGVRPFGVSLLIAGID-KNEARLFETDPSGALIEYKATAIGSGRPVVMEL 176 + + RPFGV+LLIAG D + +LF +PSG Y A AIGSG Sbjct: 125 FGEGASGEERLMSRPFGVALLIAGHDADDGYQLFHAEPSGTFYRYNAKAIGSGSEGAQAE 184 Query: 177 LEKEYRDDITLDEGLELAITALTKANED-IKPENVDVCIITVKDAQFKKIPVEEIKKLIE 235 L E+ +TL E L + L + E+ + N + IT +D FK E+ +LI+ Sbjct: 185 LLNEWHSSLTLKEAELLVLKILKQVMEEKLDENNAQLSCITKQDG-FKIYDNEKTAELIK 243 Query: 236 KVKKKLNEENKKEEE 250 ++K+K E+ +E + Sbjct: 244 ELKEKEAAESPEEAD 258 >1IRU-A nrPDB Length = 246 Score = 252 bits (644), Expect = 1e-67, Method: Composition-based stats. Identities = 83/239 (34%), Positives = 146/239 (61%), Gaps = 5/239 (2%) Query: 7 SAYDRAITVFSPEGRLYQVEYAREAVRRGT-TAIGIACKDGVVLAVDRRITSKLVKIRSI 65 + +DR IT+FSPEGRLYQVEYA +A+ +G T++ + KD V+ +++ KL+ ++ Sbjct: 7 AGFDRHITIFSPEGRLYQVEYAFKAINQGGLTSVAVRGKDCAVIVTQKKVPDKLLDSSTV 66 Query: 66 EKIFQIDDHVAAATSGLVADARVLIDRARLEAQIYRLTYGEEISIEMLAKKICDIKQAYT 125 +F+I +++ +G+ AD+R + RAR EA ++ YG EI ++ML K+I DI Q YT Sbjct: 67 THLFKITENIGCVMTGMTADSRSQVQRARYEAANWKYKYGYEIPVDMLCKRIADISQVYT 126 Query: 126 QHGGVRPFGVSLLIAGID-KNEARLFETDPSGALIEYKATAIGSGRPVVMELLEKEYRD- 183 Q+ +RP G +++ GID + ++++ DP+G +KATA G + LEK+ + Sbjct: 127 QNAEMRPLGCCMILIGIDEEQGPQVYKCDPAGYYCGFKATAAGVKQTESTSFLEKKVKKK 186 Query: 184 -DITLDEGLELAITALTKA-NEDIKPENVDVCIITVKDAQFKKIPVEEIKKLIEKVKKK 240 D T ++ +E AIT L+ + D KP ++V ++TV++ +F+ + EI + + ++ Sbjct: 187 FDWTFEQTVETAITCLSTVLSIDFKPSEIEVGVVTVENPKFRILTEAEIDAHLVALAER 245 >2KU2-A nrPDB Length = 237 Score = 251 bits (640), Expect = 4e-67, Method: Composition-based stats. Identities = 119/236 (50%), Positives = 170/236 (72%), Gaps = 3/236 (1%) Query: 1 MQMVP-PSAYDRAITVFSPEGRLYQVEYAREAVRRGTTAIGIACKDGVVLAVDRRITSKL 59 M M A RAITVFSP+GRL+QVEYAREAV++G+TA+G+ +GV+L D+++ S+L Sbjct: 3 MGMQQGQMAGGRAITVFSPDGRLFQVEYAREAVKKGSTALGMKFANGVLLISDKKVRSRL 62 Query: 60 VKIRSIEKIFQIDDHVAAATSGLVADARVLIDRARLEAQIYRLTYGEEISIEMLAKKICD 119 ++ SIEKI IDD+VAA TSGLVADARVL+D AR+ AQ ++TYG ++IE L K++ D Sbjct: 63 IEQNSIEKIQLIDDYVAAVTSGLVADARVLVDFARISAQQEKVTYGSLVNIENLVKRVAD 122 Query: 120 IKQAYTQHGGVRPFGVSLLIAGIDKNEARLFETDPSGALIEYKATAIGSGRPVVMELLEK 179 Q YTQ+GGVRP+GVSL+ AGID+ RLF+ DP+G + EYKATAIGSG+ V+ LE+ Sbjct: 123 QMQQYTQYGGVRPYGVSLIFAGIDQIGPRLFDCDPAGTINEYKATAIGSGKDAVVSFLER 182 Query: 180 EYRDDITLDEGLELAITALTKANEDIKP-ENVDVCIITVKDAQFKKIPVEEIKKLI 234 EY++++ E + L I AL + E+ + + ++ ITV + +++ EE+KK + Sbjct: 183 EYKENLPEKEAVTLGIKALKSSLEEGEELKAPEIASITVGN-KYRIYDQEEVKKFL 237 >5LEZ-C nrPDB Length = 248 Score = 250 bits (639), Expect = 4e-67, Method: Composition-based stats. Identities = 103/232 (44%), Positives = 154/232 (66%), Gaps = 5/232 (2%) Query: 7 SAYDRAITVFSPEGRLYQVEYAREAVRRGTTAIGIACKDGVVLAVDRRITSKLVKIRSIE 66 +YDRAITVFSP+G L+QVEYA+EAV++G+TA+G+ +D VVL V+++ +KL R++ Sbjct: 1 MSYDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGRDIVVLGVEKKSVAKLQDERTVR 60 Query: 67 KIFQIDDHVAAATSGLVADARVLIDRARLEAQIYRLTYGEEISIEMLAKKICDIKQAYTQ 126 KI +DD+V A +GL ADAR++I+RAR+E Q +RLT + +++E + + I +KQ YTQ Sbjct: 61 KICALDDNVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQ 120 Query: 127 HGGVRPFGVSLLIAGIDKNE-ARLFETDPSGALIEYKATAIGSGRPVVMELLEKEYRDD- 184 G RPFG+S LI G D + RL++TDPSG +KA AIG G V E LEK Y D+ Sbjct: 121 SNGRRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKNYTDEA 180 Query: 185 -ITLDEGLELAITALTKANEDIKPENVDVCIITVKDAQFKKIPVEEIKKLIE 235 T D ++L I AL + + +N+++ ++ +D K + EEI+K + Sbjct: 181 IETDDLTIKLVIKALLEVVQSG-GKNIELAVM-RRDQSLKILNPEEIEKYVA 230 >5LF0-A nrPDB Length = 234 Score = 249 bits (636), Expect = 8e-67, Method: Composition-based stats. Identities = 91/232 (39%), Positives = 134/232 (57%), Gaps = 3/232 (1%) Query: 8 AYDRAITVFSPEGRLYQVEYAREAVRRGTTAIGIACKDGVVLAVDRRITSKLVKIRSIEK 67 Y ++T FSP G+L Q+EYA AV G ++GI +GVVLA +++ S L RS+ K Sbjct: 5 GYSFSLTTFSPSGKLVQIEYALAAVAGGAPSVGIKAANGVVLATEKKQKSILYDERSVHK 64 Query: 68 IFQIDDHVAAATSGLVADARVLIDRARLEAQIYRLTYGEEISIEMLAKKICDIKQAYTQH 127 + I H+ SG+ D RVL+ RAR AQ Y L Y E I L +++ + Q YTQ Sbjct: 65 VEPITKHIGLVYSGMGPDYRVLVHRARKLAQQYYLVYQEPIPTAQLVQRVASVMQEYTQS 124 Query: 128 GGVRPFGVSLLIAGIDKNEARLFETDPSGALIEYKATAIGSGRPVVMELLEKEYRDDITL 187 GGVRPFGVSLLI G ++ LF++DPSGA +KATA+G LEK Y +D+ L Sbjct: 125 GGVRPFGVSLLICGWNEGRPYLFQSDPSGAYFAWKATAMGKNYVNGKTFLEKRYNEDLEL 184 Query: 188 DEGLELAITALTKANE-DIKPENVDVCIITVKDAQFKKIPVEEIKKLIEKVK 238 ++ + AI L ++ E + +N++V I +A F+++ E+K + + Sbjct: 185 EDAIHTAILTLKESFEGQMTEDNIEVGI--CNEAGFRRLTPTEVKDYLAAIA 234 >1G0U-D nrPDB Length = 241 Score = 249 bits (635), Expect = 1e-66, Method: Composition-based stats. Identities = 106/243 (43%), Positives = 148/243 (60%), Gaps = 6/243 (2%) Query: 4 VPPSAYDRAITVFSPEGRLYQVEYAREAVRRGTTAIGIACKDGVVLAVDRRITSKLVKIR 63 + S YDR ++ FSPEGRL+QVEY+ EA++ G+TAIGIA K+GVVL V++R TS L++ Sbjct: 3 LTRSEYDRGVSTFSPEGRLFQVEYSLEAIKLGSTAIGIATKEGVVLGVEKRATSPLLESD 62 Query: 64 SIEKIFQIDDHVAAATSGLVADARVLIDRARLEAQIYRLTYGEEISIEMLAKKICDIKQA 123 SIEKI +ID H+ A SGL ADAR +I+ AR A + L Y E+I++E L + +CD+ A Sbjct: 63 SIEKIVEIDRHIGCAMSGLTADARSMIEHARTAAVTHNLYYDEDINVESLTQSVCDLAAA 122 Query: 124 YTQHGGVRPFGVSLLIAGID-KNEARLFETDPSGALIEYKATAIGSGRPVVMELLEKEYR 182 RPFGV+LLIAG D + +LF +PSG Y A AIGSG L E+ Sbjct: 123 AAMS---RPFGVALLIAGHDADDGYQLFHAEPSGTFYRYNAKAIGSGSEGAQAELLNEWH 179 Query: 183 DDITLDEGLELAITALTKANED-IKPENVDVCIITVKDAQFKKIPVEEIKKLIEKVKKKL 241 +TL E L + L + E+ + N + IT +D FK E+ +LI+++K+K Sbjct: 180 SSLTLKEAELLVLKILKQVMEEKLDENNAQLSCITKQDG-FKIYDNEKTAELIKELKEKE 238 Query: 242 NEE 244 E Sbjct: 239 AAE 241 >5GJR-F nrPDB Length = 241 Score = 249 bits (635), Expect = 1e-66, Method: Composition-based stats. Identities = 92/240 (38%), Positives = 146/240 (60%), Gaps = 7/240 (2%) Query: 4 VPPSAYDRAITVFSPEGRLYQVEYAREAVRRGTTAIGIACKDGVVLAVDRRITSKLVKIR 63 + S YDR + FSPEGRL+QVEYA EA++ G+TAIGI +GV LAV++RITS L++ Sbjct: 3 LTRSEYDRGVNTFSPEGRLFQVEYAIEAIKLGSTAIGIQTSEGVCLAVEKRITSPLMEPS 62 Query: 64 SIEKIFQIDDHVAAATSGLVADARVLIDRARLEAQIYRLTYGEEISIEMLAKKICDIKQA 123 SIEKI +ID H+ A SGL+ADA+ LID+AR+E Q + TY E +++E + + + ++ Sbjct: 63 SIEKIVEIDAHIGCAMSGLIADAKTLIDKARVETQNHWFTYNETMTVESVTQAVSNLALQ 122 Query: 124 YTQ-----HGGVRPFGVSLLIAGIDKNEARLFETDPSGALIEYKATAIGSGRPVVMELLE 178 + + RPFGV+LL G+D+ +LF DPSG ++ A AIGS L+ Sbjct: 123 FGEEDADPGAMSRPFGVALLFGGVDEKGPQLFHMDPSGTFVQCDARAIGSASEGAQSSLQ 182 Query: 179 KEYRDDITLDEGLELAITALTKANED-IKPENVDVCIITVKDAQFKKIPVEEIKKLIEKV 237 + Y +TL E ++ ++ L + E+ + N+++ + F EE++++I+ + Sbjct: 183 EVYHKSMTLKEAIKSSLIILKQVMEEKLNATNIELATV-QPGQNFHMFTKEELEEVIKDI 241 >6FVW-g nrPDB Length = 245 Score = 247 bits (631), Expect = 4e-66, Method: Composition-based stats. Identities = 90/243 (37%), Positives = 141/243 (58%), Gaps = 7/243 (2%) Query: 7 SAYDRAITVFSPEGRLYQVEYAREAVRRGTTAIGIACKDGVVLAVDRRITSKLVKIRSIE 66 + YD + +VFSP+GR +QVEYA +AV GTT+IGI C DGVV AV++ ITSKL+ + Sbjct: 3 TGYDLSNSVFSPDGRNFQVEYAVKAVENGTTSIGIKCNDGVVFAVEKLITSKLLVPQKNV 62 Query: 67 KIFQIDDHVAAATSGLVADARVLIDRARLEAQIYRLTYGEEISIEMLAKKICDIKQAYTQ 126 KI +D H+ SGL+ D R L++R R EA ++ Y I I A ++ QA+T Sbjct: 63 KIQVVDRHIGCVYSGLIPDGRHLVNRGREEAASFKKLYKTPIPIPAFADRLGQYVQAHTL 122 Query: 127 HGGVRPFGVSLLIAGIDKNEARLFETDPSGALIEYKATAIGSGRPVVMELLEK---EYRD 183 + VRPFGVS + G+DKN A L+ +PSG+ YK A G GR LEK + + Sbjct: 123 YNSVRPFGVSTIFGGVDKNGAHLYMLEPSGSYWGYKGAATGKGRQSAKAELEKLVDHHPE 182 Query: 184 DITLDEGLELAITALTKANEDIKPENVDV----CIITVKDAQFKKIPVEEIKKLIEKVKK 239 ++ E ++ A + A+ED K ++ ++ C ++ + K + + +++ I+ +K Sbjct: 183 GLSAREAVKQAAKIIYLAHEDNKEKDFELEISWCSLSETNGLHKFVKGDLLQEAIDFAQK 242 Query: 240 KLN 242 ++N Sbjct: 243 EIN 245 >5FGG-F nrPDB Length = 288 Score = 246 bits (628), Expect = 7e-66, Method: Composition-based stats. Identities = 90/243 (37%), Positives = 141/243 (58%), Gaps = 7/243 (2%) Query: 7 SAYDRAITVFSPEGRLYQVEYAREAVRRGTTAIGIACKDGVVLAVDRRITSKLVKIRSIE 66 + YD + +VFSP+GR +QVEYA +AV GTT+IGI C DGVV AV++ ITSKL+ + Sbjct: 6 TGYDLSNSVFSPDGRNFQVEYAVKAVENGTTSIGIKCNDGVVFAVEKLITSKLLVPQKNV 65 Query: 67 KIFQIDDHVAAATSGLVADARVLIDRARLEAQIYRLTYGEEISIEMLAKKICDIKQAYTQ 126 KI +D H+ SGL+ D R L++R R EA ++ Y I I A ++ QA+T Sbjct: 66 KIQVVDRHIGCVYSGLIPDGRHLVNRGREEAASFKKLYKTPIPIPAFADRLGQYVQAHTL 125 Query: 127 HGGVRPFGVSLLIAGIDKNEARLFETDPSGALIEYKATAIGSGRPVVMELLEK---EYRD 183 + VRPFGVS + G+DKN A L+ +PSG+ YK A G GR LEK + + Sbjct: 126 YNSVRPFGVSTIFGGVDKNGAHLYMLEPSGSYWGYKGAATGKGRQSAKAELEKLVDHHPE 185 Query: 184 DITLDEGLELAITALTKANEDIKPENVDV----CIITVKDAQFKKIPVEEIKKLIEKVKK 239 ++ E ++ A + A+ED K ++ ++ C ++ + K + + +++ I+ +K Sbjct: 186 GLSAREAVKQAAKIIYLAHEDNKEKDFELEISWCSLSETNGLHKFVKGDLLQEAIDFAQK 245 Query: 240 KLN 242 ++N Sbjct: 246 EIN 248 >5LE5-B nrPDB Length = 261 Score = 244 bits (623), Expect = 3e-65, Method: Composition-based stats. Identities = 98/233 (42%), Positives = 146/233 (62%), Gaps = 7/233 (3%) Query: 9 YDRAITVFSPEGRLYQVEYAREAVRRGTTAIGIACKDGVVLAVDRRITSKLVKIRSI-EK 67 YD T+FSPEGRLYQVEYA EA+ T +GI DGV+LA +RR KL+ EK Sbjct: 5 YDSRTTIFSPEGRLYQVEYAMEAIGHAGTCLGILANDGVLLAAERRNIHKLLDEVFFSEK 64 Query: 68 IFQIDDHVAAATSGLVADARVLIDRARLEAQIYRLTYGEEISIEMLAKKICDIKQAYTQH 127 I+++++ +A + +G+ +DA VL + RL AQ Y L Y E I E L +CDIKQAYTQ Sbjct: 65 IYKLNEDMACSVAGITSDANVLTNELRLIAQRYLLQYQEPIPCEQLVTALCDIKQAYTQF 124 Query: 128 GGVRPFGVSLLIAGIDKN-EARLFETDPSGALIEYKATAIGSGRPVVMELLEKEYRD-DI 185 GG RPFGVSLL G DK+ +L+++DPSG +KAT IG+ + +L+++Y++ ++ Sbjct: 125 GGKRPFGVSLLYIGWDKHYGFQLYQSDPSGNYGGWKATCIGNNSAAAVSMLKQDYKEGEM 184 Query: 186 TLDEGLELAITALTKANE--DIKPENVDVCIITVKDAQ--FKKIPVEEIKKLI 234 TL L LAI L K + + E V++ +T ++ + + + +E+++LI Sbjct: 185 TLKSALALAIKVLNKTMDVSKLSAEKVEIATLTRENGKTVIRVLKQKEVEQLI 237 >5FMG-C nrPDB Length = 246 Score = 240 bits (614), Expect = 3e-64, Method: Composition-based stats. Identities = 106/242 (43%), Positives = 155/242 (64%), Gaps = 6/242 (2%) Query: 9 YDRAITVFSPEGRLYQVEYAREAVRRGTTAIGIACKDGVVLAVDRRITSKLVK-IRSIEK 67 YD T FSPEGRLYQVEYA EA+ + IG+ KDGV+L D+ SKL+ + EK Sbjct: 5 YDSRTTTFSPEGRLYQVEYALEAINNASITIGLITKDGVILGADKVFISKLIDKANNYEK 64 Query: 68 IFQIDDHVAAATSGLVADARVLIDRARLEAQIYRLTYGEEISIEMLAKKICDIKQAYTQH 127 I++ID H+ +GL ADA +LI+++RL AQ Y Y E + L +ICDIKQ+YTQ+ Sbjct: 65 IYKIDKHIFCGVAGLNADANILINQSRLYAQRYLYNYNEVQPVSQLVVQICDIKQSYTQY 124 Query: 128 GGVRPFGVSLLIAGID-KNEARLFETDPSGALIEYKATAIGSGRPVVMELLEKEYRDDIT 186 GG+RP+GVS LI G D K+ +L+ TDPSG + ATAIG+ +L++E+++D+T Sbjct: 125 GGLRPYGVSFLIGGYDTKDGYQLYHTDPSGNYSGWFATAIGTNNLTASSVLKQEWKNDMT 184 Query: 187 LDEGLELAITALTKANED--IKPENVDVCIITVKDAQF--KKIPVEEIKKLIEKVKKKLN 242 L+EGL LA+ L K+ + K E +++ +T KD + K + +EI++LI+ +K Sbjct: 185 LEEGLLLALKTLAKSTDTEIPKSEKIELAYLTNKDGEVYQKYLTEKEIEELIKLYTQKYI 244 Query: 243 EE 244 +E Sbjct: 245 KE 246 >5FMG-B nrPDB Length = 235 Score = 240 bits (614), Expect = 3e-64, Method: Composition-based stats. Identities = 88/232 (37%), Positives = 136/232 (58%), Gaps = 2/232 (0%) Query: 8 AYDRAITVFSPEGRLYQVEYAREAVRRGTTAIGIACKDGVVLAVDRRITSKLVKIRSIEK 67 Y ++T FSP G+L Q+EYA V + A+GI K+GV++A +++ ++L++ SI K Sbjct: 5 EYSFSLTTFSPTGKLVQIEYALNRVSSSSPALGIRAKNGVIIATEKKSPNELIEENSIFK 64 Query: 68 IFQIDDHVAAATSGLVADARVLIDRARLEAQIYRLTYGEEISIEMLAKKICDIKQAYTQH 127 I QI +H+ +G+ D RVL+ RAR EA Y L YG EI ++ L K I I Q +TQ Sbjct: 65 IQQISEHIGIVYAGMPGDFRVLLKRARKEAIRYSLQYGSEILVKELVKIIASIVQEFTQT 124 Query: 128 GGVRPFGVSLLIAGIDKNEARLFETDPSGALIEYKATAIGSGRPVVMELLEKEYRDDITL 187 GGVRPFG+SLLI G+D L++ DPSG + AT +G M LEK Y DI + Sbjct: 125 GGVRPFGLSLLICGVDVYGYHLYQIDPSGCYFNWMATCVGKDYQNNMSFLEKRYNKDIEI 184 Query: 188 DEGLELAITALTKANED-IKPENVDVCIITVKDAQFKKIPVEEIKKLIEKVK 238 ++ + AI L ++ E + +N+++ + + FK + EIK + +++ Sbjct: 185 EDAIHTAILTLKESYEGVLNEKNIEIGV-AYDNKPFKILTQNEIKDYLIEIE 235 >4FZC-A nrPDB Length = 250 Score = 235 bits (599), Expect = 2e-62, Method: Composition-based stats. Identities = 87/246 (35%), Positives = 142/246 (57%), Gaps = 17/246 (6%) Query: 9 YDRAITVFSPEGRLYQVEYAREAVRRGTTAIGIACKDGVVLAVDRRITSKLVKIRSIEKI 68 Y ++T FSP G+L Q++YA AV++G T++GI +GVV+A +++ +S L ++ K+ Sbjct: 5 YSFSLTTFSPSGKLGQIDYALTAVKQGVTSLGIKATNGVVIATEKKSSSPLAMSETLSKV 64 Query: 69 FQIDDHVAAATSGLVADARVLIDRARLEAQI-YRLTYGEEISIEMLAKKICDIKQAYTQH 127 + + A SG+ D RVL+D++R A Y+ YGE ++L ++ I Q TQ Sbjct: 65 SLLTPDIGAVYSGMGPDYRVLVDKSRKVAHTSYKRIYGEYPPTKLLVSEVAKIMQEATQS 124 Query: 128 GGVRPFGVSLLIAGIDK-NEARLFETDPSGALIEYKATAIGSGRPVVMELLEKEYRDDIT 186 GGVRPFGVSLLIAG D+ N L++ DPSG+ +KATAIG G LEK + D++ Sbjct: 125 GGVRPFGVSLLIAGHDEFNGFSLYQVDPSGSYFPWKATAIGKGSVAAKTFLEKRWNDELE 184 Query: 187 LDEGLELAITALTKANE-DIKPENVDVCII--------------TVKDAQFKKIPVEEIK 231 L++ + +A+ L ++ E + + +++ II T K +F+K+ +EI Sbjct: 185 LEDAIHIALLTLKESVEGEFNGDTIELAIIGDENPDLLGYTGIPTDKGPRFRKLTSQEIN 244 Query: 232 KLIEKV 237 +E + Sbjct: 245 DRLEAL 250 >6J30-C nrPDB Length = 258 Score = 233 bits (594), Expect = 7e-62, Method: Composition-based stats. Identities = 98/236 (41%), Positives = 151/236 (63%), Gaps = 8/236 (3%) Query: 9 YDRAITVFSPEGRLYQVEYAREAVRRGTTAIGIACKDGVVLAVDRRITSKLVK-IRSIEK 67 YD T+FSPEGRLYQVEYA E++ TAIGI DG+VLA +R++TS L++ S EK Sbjct: 6 YDSRTTIFSPEGRLYQVEYALESISHAGTAIGIMASDGIVLAAERKVTSTLLEQDTSTEK 65 Query: 68 IFQIDDHVAAATSGLVADARVLIDRARLEAQIYRLTYGEEISIEMLAKKICDIKQAYTQH 127 +++++D +A A +GL ADA +LI+ AR+ AQ Y TY E+I +E+L +++ DIKQ YTQH Sbjct: 66 LYKLNDKIAVAVAGLTADAEILINTARIHAQNYLKTYNEDIPVEILVRRLSDIKQGYTQH 125 Query: 128 GGVRPFGVSLLIAGIDKNEA-RLFETDPSGALIEYKATAIGSGRPVVMELLEKEYRDDIT 186 GG+RPFGVS + AG D +L+ ++PSG +KA ++G+ LL+ +Y+DD+ Sbjct: 126 GGLRPFGVSFIYAGYDDRYGYQLYTSNPSGNYTGWKAISVGANTSAAQTLLQMDYKDDMK 185 Query: 187 LDEGLELAITALTKANED--IKPENVDVCIITV----KDAQFKKIPVEEIKKLIEK 236 +D+ +ELA+ L+K + + + ++ I + K +EIK ++ K Sbjct: 186 VDDAIELALKTLSKTTDSSALTYDRLEFATIRKGANDGEVYQKIFKPQEIKDILVK 241 >5FMG-F nrPDB Length = 254 Score = 229 bits (585), Expect = 8e-61, Method: Composition-based stats. Identities = 86/255 (33%), Positives = 143/255 (56%), Gaps = 11/255 (4%) Query: 9 YDRAITVFSPEGRLYQVEYAREAVRRGTTAIGIACKDGVVLAVDRRITSKLVKIRSIEKI 68 YD ++SPEGRLYQVEYA EA+++GT A+ I KD VV++ ++ SKL + EKI Sbjct: 6 YDTDNIIYSPEGRLYQVEYASEAIKQGTCAVAIKSKDYVVVSGLKKCISKLSFPQ--EKI 63 Query: 69 FQIDDHVAAATSGLVADARVLIDRARLEAQIYRLTYGEEISIEMLAKKICDIKQAYTQHG 128 F+IDD++ + SG+ +DA+VL + E ++ Y E I+IE L + + D Q TQ Sbjct: 64 FKIDDYIGISMSGITSDAKVLTKFMQNECLSHKFLYNENINIESLVRSVADKYQKNTQKS 123 Query: 129 GVRPFGVSLLIAGIDKNEARLFETDPSGALIEYKATAIGSGRPVVMELLEKEYR--DDIT 186 R FGV L+IA NE +FET P+G+ EY A + G+ LEK ++ + Sbjct: 124 SKRAFGVGLMIAAY-HNEPCIFETRPNGSYFEYDALSFGARSHASKTYLEKNLHLFEECS 182 Query: 187 LDEGLELAITALT---KANEDIKPENVDVCIITVKDAQFKKIPVEEIKKLIEKVKKKLNE 243 L+E + + AL + ++ N + ++ K+ +++I ++++ + KV K++ Sbjct: 183 LEELILHCLKALKCSLSSESELTISNTALAVVG-KNHPWQEISSLQLEEYLSKV--KMDA 239 Query: 244 ENKKEEENREETKEK 258 E ++ EEN + + Sbjct: 240 EQEQVEENVQNEANE 254 >3NZW-E nrPDB Length = 234 Score = 219 bits (559), Expect = 9e-58, Method: Composition-based stats. Identities = 77/232 (33%), Positives = 121/232 (52%), Gaps = 9/232 (3%) Query: 9 YDRAITVFSPEGRLYQVEYAREAVRRGTTAIGIACKDGVVLAVDRRITSKLVKIRSIEKI 68 YD FSP GRL+QVEYA EA+++G+ +G+ VL +R +L + +KI Sbjct: 6 YDGDTVTFSPTGRLFQVEYALEAIKQGSVTVGLRSNTHAVLVALKRNADELSSYQ--KKI 63 Query: 69 FQIDDHVAAATSGLVADARVLIDRARLEAQIYRLTYGEEISIEMLAKKICDIKQAYTQHG 128 + D+H+ + +GL DARVL + R + L + ++++E +CD Q TQ Sbjct: 64 IKCDEHMGLSLAGLAPDARVLSNYLRQQCNYSSLVFNRKLAVERAGHLLCDKAQKNTQSY 123 Query: 129 GVRPFGVSLLIAGIDKNEARLFETDPSGALIEYKATAIGSGRPVVMELLEKE----YRDD 184 G RP+GV LLI G DK+ A L E PSG + E TAIG+ LE+ + D Sbjct: 124 GGRPYGVGLLIIGYDKSGAHLLEFQPSGNVTELYGTAIGARSQGAKTYLERTLDTFIKID 183 Query: 185 ITLDEGLELAITALTKA--NEDIKPENVDVCIITVKDAQFKKIPVEEIKKLI 234 DE ++ + A++++ +E + +N+ + I+ KD F E + K I Sbjct: 184 GNPDELIKAGVEAISQSLRDESLTVDNLSIAIVG-KDTPFTIYDGEAVAKYI 234 >5L5A-K nrPDB Length = 211 Score = 219 bits (558), Expect = 1e-57, Method: Composition-based stats. Identities = 47/212 (22%), Positives = 89/212 (41%), Gaps = 5/212 (2%) Query: 36 TTAIGIACKDGVVLAVDRRIT-SKLVKIRSIEKIFQIDDHVAAATSGLVADARVLIDRAR 94 TT + + GV+ AVD R + + + K+ +I+ ++ SG AD + Sbjct: 1 TTTLAFKFQHGVIAAVDSRASAGSYISALRVNKVIEINPYLLGTMSGCAADCQYWETLLA 60 Query: 95 LEAQIYRLTYGEEISIEMLAKKICDIKQAYTQHGGVRPFGVSLLIAGIDKNEARLFETDP 154 E ++Y L GE IS+ +K + ++ Y G + +I G DK L+ D Sbjct: 61 KECRLYYLRNGERISVSAASKLLSNMMCQYRGMG----LSMGSMICGWDKKGPGLYYVDE 116 Query: 155 SGALIEYKATAIGSGRPVVMELLEKEYRDDITLDEGLELAITALTKANEDIKPENVDVCI 214 G + + GSG +L+ Y+ D+++++ L L ++ A V + Sbjct: 117 HGTRLSGNMFSTGSGNTYAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSVNL 176 Query: 215 ITVKDAQFKKIPVEEIKKLIEKVKKKLNEENK 246 V + + ++ +L KVK++ N Sbjct: 177 YHVTEDGWIYHGNHDVGELFWKVKEEEGSFNN 208 >6EPD-G nrPDB Length = 255 Score = 217 bits (552), Expect = 5e-57, Method: Composition-based stats. Identities = 82/249 (32%), Positives = 141/249 (56%), Gaps = 4/249 (1%) Query: 7 SAYDRAITVFSPEGRLYQVEYAREAVRRGTTAIGIACKDGVVLAVDRRITSKLVKIRSIE 66 + YD + + FSP+GR++QVEYA +AV +TAIGI CKDGVV V++ + SKL + S + Sbjct: 6 TGYDLSASTFSPDGRVFQVEYAMKAVENSSTAIGIRCKDGVVFGVEKLVLSKLYEEGSNK 65 Query: 67 KIFQIDDHVAAATSGLVADARVLIDRARLEAQIYRLTYGEEISIEMLAKKICDIKQAYTQ 126 ++F +D HV A +GL+ADAR L D AR EA +R +G I ++ LA ++ AYT Sbjct: 66 RLFNVDRHVGMAVAGLLADARSLADIAREEASNFRSNFGYNIPLKHLADRVAMYVHAYTL 125 Query: 127 HGGVRPFGVSLLIAGIDKNEA-RLFETDPSGALIEYKATAIGSGRPVVMELLEKEYRDDI 185 + VRPFG S ++ N+ +L+ DPSG Y AIG R +EK ++ Sbjct: 126 YSAVRPFGCSFMLGSYSVNDGAQLYMIDPSGVSYGYWGCAIGKARQAAKTEIEKLQMKEM 185 Query: 186 TLDEGLELAITALTKANEDIKPENVDVC---IITVKDAQFKKIPVEEIKKLIEKVKKKLN 242 T + ++ + ++++K + ++ + + + + +P + ++ + K+ L Sbjct: 186 TCRDVVKEVAKIIYIVHDEVKDKAFELELSWVGELTKGRHEIVPKDVREEAEKYAKESLK 245 Query: 243 EENKKEEEN 251 EE++ +++N Sbjct: 246 EEDESDDDN 254 >5FMG-A nrPDB Length = 260 Score = 215 bits (549), Expect = 1e-56, Method: Composition-based stats. Identities = 84/259 (32%), Positives = 136/259 (52%), Gaps = 21/259 (8%) Query: 3 MVPPS--AYDRAITVFSPEGRLYQVEYAREAVRR-GTTAIGIACKDGVVLAVDRR----- 54 MV PS YDR +T+FSP+G LYQ+EYA +AV+ T++G+ ++ V+ ++ Sbjct: 1 MVRPSQSMYDRHLTIFSPDGNLYQIEYAIKAVKNTNITSVGVKGENCAVIISQKKMATQY 60 Query: 55 -ITSKLVKIRSIEKIFQIDDHVAAATSGLVADARVLIDRARLEAQIYRLTYGEEISIEML 113 KL+ +I I+ I D + + G+ D ++ +AR EA + + G ++ E L Sbjct: 61 ISQDKLLDYNNITNIYNITDEIGCSMVGMPGDCLSMVYKARSEASEFLYSNGYNVNAETL 120 Query: 114 AKKICDIKQAYTQHGGVRPFGVSLLIAGIDK-NEARLFETDPSGALIEYKATAIGSGRPV 172 + ICD Q YTQH +R S +I GID+ N+ LF+ DPSG Y+A IG+ Sbjct: 121 CRNICDKIQVYTQHAYMRLHACSGMIIGIDENNKPELFKFDPSGFCAGYRACVIGNKEQE 180 Query: 173 VMELLE------KEYRDDITLDEGLE----LAITAL-TKANEDIKPENVDVCIITVKDAQ 221 + +LE K+ T+DE + LAI AL T D+K ++V I++ K+ Sbjct: 181 SISVLERLLEKRKKKIQQETIDEDIRNTTILAIEALQTILAFDLKASEIEVAIVSTKNRN 240 Query: 222 FKKIPVEEIKKLIEKVKKK 240 F +I +EI + + ++ Sbjct: 241 FTQISEKEIDNYLTYIAER 259 >5L64-K nrPDB Length = 211 Score = 214 bits (546), Expect = 2e-56, Method: Composition-based stats. Identities = 46/212 (21%), Positives = 92/212 (43%), Gaps = 5/212 (2%) Query: 36 TTAIGIACKDGVVLAVDRRITSK-LVKIRSIEKIFQIDDHVAAATSGLVADARVLIDRAR 94 TT + + GV++A D R T+ + ++++K+ +I+ ++ +G AD Sbjct: 1 TTTLAFKFRHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAADCSFWERLLA 60 Query: 95 LEAQIYRLTYGEEISIEMLAKKICDIKQAYTQHGGVRPFGVSLLIAGIDKNEARLFETDP 154 + +IY L E IS+ +K + ++ Y G + +I G DK L+ D Sbjct: 61 RQCRIYELRNKERISVAAASKLLANMVYQYKGMG----LSMGTMICGWDKRGPGLYYVDS 116 Query: 155 SGALIEYKATAIGSGRPVVMELLEKEYRDDITLDEGLELAITALTKANEDIKPENVDVCI 214 G I ++GSG +L+ Y+ D+++++ L L ++ A V + Sbjct: 117 EGNRISGATFSVGSGSVYAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSVNL 176 Query: 215 ITVKDAQFKKIPVEEIKKLIEKVKKKLNEENK 246 V + + ++ +L KVK++ N Sbjct: 177 YHVTEDGWIYHGNHDVGELFWKVKEEEGSFNN 208 >3NZW-K nrPDB Length = 287 Score = 212 bits (541), Expect = 9e-56, Method: Composition-based stats. Identities = 43/217 (19%), Positives = 94/217 (43%), Gaps = 6/217 (2%) Query: 32 VRRGTTAIGIACKDGVVLAVDRRIT-SKLVKIRSIEKIFQIDDHVAAATSGLVADARVLI 90 + GTT + + G+++AVD R T V ++++K+ +I+ + +G AD + Sbjct: 72 IAHGTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWE 131 Query: 91 DRARLEAQIYRLTYGEEISIEMLAKKICDIKQAYTQHGGVRPFGVSLLIAGID-KNEARL 149 + +++ L E IS+ +K + ++ Y G + +I G K + Sbjct: 132 TWLGSQCRLHELREKERISVAAASKILSNLVYQYKGAG----LSMGTMICGYTRKEGPTI 187 Query: 150 FETDPSGALIEYKATAIGSGRPVVMELLEKEYRDDITLDEGLELAITALTKANEDIKPEN 209 + D G ++ +GSG+ +L+ Y+ D+++++ L L ++ A Sbjct: 188 YYVDSDGTRLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSG 247 Query: 210 VDVCIITVKDAQFKKIPVEEIKKLIEKVKKKLNEENK 246 V + V + + ++ +L KVK++ N Sbjct: 248 GSVNLYHVTEDGWIYHGNHDVGELFWKVKEEEGSFNN 284 >6EPF-5 nrPDB Length = 263 Score = 207 bits (528), Expect = 3e-54, Method: Composition-based stats. Identities = 46/210 (21%), Positives = 93/210 (44%), Gaps = 5/210 (2%) Query: 34 RGTTAIGIACKDGVVLAVDRRIT-SKLVKIRSIEKIFQIDDHVAAATSGLVADARVLIDR 92 GTT + + GV++A D R T + ++++K+ +I+ ++ +G AD Sbjct: 58 HGTTTLAFKFQHGVIVAADSRATAGPYIASQTVKKVIEINPYLLGTMAGGAADCSFWERL 117 Query: 93 ARLEAQIYRLTYGEEISIEMLAKKICDIKQAYTQHGGVRPFGVSLLIAGIDKNEARLFET 152 + +IY L E IS+ +K + ++ Y G + +I G DK L+ Sbjct: 118 LARQCRIYELRNKERISVAAASKLLANMVYQYKGMG----LSMGTMICGWDKRGPGLYYV 173 Query: 153 DPSGALIEYKATAIGSGRPVVMELLEKEYRDDITLDEGLELAITALTKANEDIKPENVDV 212 D G I A ++GSG ++++ Y D+ ++E +LA A+ +A V Sbjct: 174 DSEGNRISGTAFSVGSGSVYAFGVMDRGYSYDLQVEEAYDLARRAIYQATYRDAYSGGAV 233 Query: 213 CIITVKDAQFKKIPVEEIKKLIEKVKKKLN 242 + V++ + ++ + + L +K + Sbjct: 234 NLYHVREDGWIRVSSDNVADLHDKYTSSIP 263 >5CZ8-K nrPDB Length = 221 Score = 207 bits (527), Expect = 4e-54, Method: Composition-based stats. Identities = 42/217 (19%), Positives = 93/217 (42%), Gaps = 6/217 (2%) Query: 32 VRRGTTAIGIACKDGVVLAVDRRIT-SKLVKIRSIEKIFQIDDHVAAATSGLVADARVLI 90 + GTT + + G+++AVD R T V ++++ + +I+ + +G AD + Sbjct: 6 IAHGTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKAVIEINPFLLGTMAGGAADCQFWE 65 Query: 91 DRARLEAQIYRLTYGEEISIEMLAKKICDIKQAYTQHGGVRPFGVSLLIAGID-KNEARL 149 + +++ L E IS+ +K + ++ Y G + +I G K + Sbjct: 66 TWLGSQCRLHELREKERISVAAASKILSNLVYQYKGAG----LSMGTMICGYTRKEGPTI 121 Query: 150 FETDPSGALIEYKATAIGSGRPVVMELLEKEYRDDITLDEGLELAITALTKANEDIKPEN 209 + D G ++ +GSG+ +L+ Y+ D+++++ L L ++ A Sbjct: 122 YYVDSDGTRLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSG 181 Query: 210 VDVCIITVKDAQFKKIPVEEIKKLIEKVKKKLNEENK 246 V + V + + ++ +L KVK++ N Sbjct: 182 GSVNLYHVTEDGWIYHGNHDVGELFWKVKEEEGSFNN 218 >6AVO-C nrPDB Length = 204 Score = 205 bits (523), Expect = 1e-53, Method: Composition-based stats. Identities = 44/205 (21%), Positives = 88/205 (42%), Gaps = 5/205 (2%) Query: 36 TTAIGIACKDGVVLAVDRRIT-SKLVKIRSIEKIFQIDDHVAAATSGLVADARVLIDRAR 94 TT + + GV+ AVD R + + + K+ +I+ ++ SG AD + Sbjct: 1 TTTLAFKFQHGVIAAVDSRASAGSYISALRVNKVIEINPYLLGTMSGCAADCQYWERLLA 60 Query: 95 LEAQIYRLTYGEEISIEMLAKKICDIKQAYTQHGGVRPFGVSLLIAGIDKNEARLFETDP 154 E ++Y L GE IS+ +K + ++ Y G + +I G DK L+ D Sbjct: 61 KECRLYYLRNGERISVSAASKLLSNMMCQYRGMG----LSMGSMICGWDKKGPGLYYVDE 116 Query: 155 SGALIEYKATAIGSGRPVVMELLEKEYRDDITLDEGLELAITALTKANEDIKPENVDVCI 214 G + + GSG +++ YR +++ +E +L A+ A V + Sbjct: 117 HGTRLSGNMFSTGSGNTYAYGVMDSGYRPNLSPEEAYDLGRRAIAYATHRDSYSGGVVNM 176 Query: 215 ITVKDAQFKKIPVEEIKKLIEKVKK 239 +K+ + K+ ++ L+ + ++ Sbjct: 177 YHMKEDGWVKVESTDVSDLLHQYRE 201 >5L5W-G nrPDB Length = 252 Score = 202 bits (514), Expect = 1e-52, Method: Composition-based stats. Identities = 73/242 (30%), Positives = 130/242 (53%), Gaps = 12/242 (4%) Query: 9 YDRAITVFSPEGRLYQVEYAREAVRR-GTTAIGIACKDGVVLAVDRRITSKLVKIRSIEK 67 YDR IT+FSPEGRLYQVEYA +A + ++ + KD V+ +++ KL+ ++ Sbjct: 12 YDRHITIFSPEGRLYQVEYAFKATNQTNINSLAVRGKDCTVVISQKKVPDKLLDPTTVSY 71 Query: 68 IFQIDDHVAAATSGLVADARVLIDRARLEAQIYRLTYGEEISIEMLAKKICDIKQAYTQH 127 IF I + +G + DAR RA+ EA +R YG ++ ++LAK++ ++ Q YTQ Sbjct: 72 IFCISRTIGMVVNGPIPDARNAALRAKAEAAEFRYKYGYDMPCDVLAKRMANLSQIYTQR 131 Query: 128 GGVRPFGVSLLIAGIDKN-EARLFETDPSGALIEYKATAIGSGRPVVMELLEKEYRD--- 183 +RP GV L +D+ +++TDP+G + YKATA G + + LE ++ Sbjct: 132 AYMRPLGVILTFVSVDEELGPSIYKTDPAGYYVGYKATATGPKQQEITTNLENHFKKSKI 191 Query: 184 ----DITLDEGLELAITALTKA-NEDIKPENVDVCIITVKDAQFKKIPVEEIKKLIEKVK 238 + + ++ +E AIT + A + +++V + T +F + E I++ + + Sbjct: 192 DHINEESWEKVVEFAITHMIDALGTEFSKNDLEVGVATK--DKFFTLSAENIEERLVAIA 249 Query: 239 KK 240 ++ Sbjct: 250 EQ 251 >3UNF-K nrPDB Length = 204 Score = 202 bits (514), Expect = 1e-52, Method: Composition-based stats. Identities = 47/205 (22%), Positives = 90/205 (43%), Gaps = 5/205 (2%) Query: 36 TTAIGIACKDGVVLAVDRRIT-SKLVKIRSIEKIFQIDDHVAAATSGLVADARVLIDRAR 94 TT + + GV++AVD R T + + K+ +I+ ++ SG AD + Sbjct: 1 TTTLAFKFQHGVIVAVDSRATAGSYISSLRMNKVIEINPYLLGTMSGCAADCQYWERLLA 60 Query: 95 LEAQIYRLTYGEEISIEMLAKKICDIKQAYTQHGGVRPFGVSLLIAGIDKNEARLFETDP 154 E ++Y L GE IS+ +K + ++ Y G + +I G DK L+ D Sbjct: 61 KECRLYYLRNGERISVSAASKLLSNMMLQYRGMG----LSMGSMICGWDKKGPGLYYVDD 116 Query: 155 SGALIEYKATAIGSGRPVVMELLEKEYRDDITLDEGLELAITALTKANEDIKPENVDVCI 214 +G + + + GSG +++ YR D++ +E +L A+ A V + Sbjct: 117 NGTRLSGQMFSTGSGNTYAYGVMDSGYRQDLSPEEAYDLGRRAIAYATHRDNYSGGVVNM 176 Query: 215 ITVKDAQFKKIPVEEIKKLIEKVKK 239 +K+ + K+ ++ L+ K + Sbjct: 177 YHMKEDGWVKVESSDVSDLLYKYGE 201 >5LN3-5 nrPDB Length = 263 Score = 200 bits (510), Expect = 4e-52, Method: Composition-based stats. Identities = 45/205 (21%), Positives = 92/205 (44%), Gaps = 5/205 (2%) Query: 34 RGTTAIGIACKDGVVLAVDRRITSK-LVKIRSIEKIFQIDDHVAAATSGLVADARVLIDR 92 GTT + + GV++A D R T+ + ++++K+ +I+ ++ +G AD Sbjct: 58 HGTTTLAFKFRHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAADCSFWERL 117 Query: 93 ARLEAQIYRLTYGEEISIEMLAKKICDIKQAYTQHGGVRPFGVSLLIAGIDKNEARLFET 152 + +IY L E IS+ +K + ++ Y G + +I G DK L+ Sbjct: 118 LARQCRIYELRNKERISVAAASKLLANMVYQYKGMG----LSMGTMICGWDKRGPGLYYV 173 Query: 153 DPSGALIEYKATAIGSGRPVVMELLEKEYRDDITLDEGLELAITALTKANEDIKPENVDV 212 D G I ++GSG ++++ Y D+ +++ +LA A+ +A V Sbjct: 174 DSEGNRISGATFSVGSGSVYAYGVMDRGYSYDLEVEQAYDLARRAIYQATYRDAYSGGAV 233 Query: 213 CIITVKDAQFKKIPVEEIKKLIEKV 237 + V++ + ++ + + L EK Sbjct: 234 NLYHVREDGWIRVSSDNVADLHEKY 258 >5FMG-G nrPDB Length = 252 Score = 200 bits (508), Expect = 6e-52, Method: Composition-based stats. Identities = 65/247 (26%), Positives = 126/247 (51%), Gaps = 8/247 (3%) Query: 7 SAYDRAITVFSPEGRLYQVEYAREAVRRGTTAIGIACKDGVVLAV--DRRITSKLVKIRS 64 + YD +++ FSP+GRLYQVEY +++ TA+ + CKDG++ +K++K S Sbjct: 6 AGYDLSVSTFSPDGRLYQVEYIYKSINNNNTALCLECKDGIICCCINSNMDKNKMIKKNS 65 Query: 65 IEKIFQIDDHVAAATSGLVADARVLIDRARLEAQIYRLTYGEEISIEMLAKKICDIKQAY 124 +I+ +++++ SG DAR +IDRAR EA Y + I + +L +I AY Sbjct: 66 YNRIYHVNNNIIITYSGFDGDARNIIDRARSEANTYYYNFHTNIPLHILVNRISLYIHAY 125 Query: 125 TQHGGVRPFGVSLLIAGID-KNEARLFETDPSGALIEYKATAIGSGRPVVMELLEKEYRD 183 T + +RPF S++I+ + K++ ++ +P+GA +Y IG + + +EK+ Sbjct: 126 TLYWHMRPFAASIIISSFNEKDKGDIYCIEPNGACYKYSGIVIGKNKEMFKTEIEKKDYK 185 Query: 184 DITLDEGLELAITALTKANEDIKPENVDVCI-----ITVKDAQFKKIPVEEIKKLIEKVK 238 DI + + +E + +++ + N+ + +F+ I E + + K Sbjct: 186 DINVRDAIEDIYKFILTSDDHMNKNNLQNLVNFSWICKESSYEFQNIHEEILTPALNKAV 245 Query: 239 KKLNEEN 245 + + + N Sbjct: 246 EYIEKLN 252 >3UNB-K nrPDB Length = 205 Score = 194 bits (492), Expect = 5e-50, Method: Composition-based stats. Identities = 45/205 (21%), Positives = 91/205 (44%), Gaps = 5/205 (2%) Query: 36 TTAIGIACKDGVVLAVDRRITSK-LVKIRSIEKIFQIDDHVAAATSGLVADARVLIDRAR 94 TT + GV++A D R T+ + ++++K+ +I+ ++ +G AD Sbjct: 1 TTTLAFKFLHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAADCSFWERLLA 60 Query: 95 LEAQIYRLTYGEEISIEMLAKKICDIKQAYTQHGGVRPFGVSLLIAGIDKNEARLFETDP 154 + +IY L E IS+ +K + ++ Y G + +I G DK L+ D Sbjct: 61 RQCRIYELRNKERISVAAASKLLANMVYQYKGMG----LSMGTMICGWDKRGPGLYYVDS 116 Query: 155 SGALIEYKATAIGSGRPVVMELLEKEYRDDITLDEGLELAITALTKANEDIKPENVDVCI 214 G I A ++GSG ++++ Y D+ ++E +LA A+ +A V + Sbjct: 117 EGNRISGTAFSVGSGSVYAYGVMDRGYSYDLKVEEAYDLARRAIYQATYRDAYSGGAVNL 176 Query: 215 ITVKDAQFKKIPVEEIKKLIEKVKK 239 V++ + ++ + + L +K Sbjct: 177 YHVREDGWIRVSSDNVADLHDKYSS 201 >3IPM-H nrPDB Length = 217 Score = 188 bits (479), Expect = 2e-48, Method: Composition-based stats. Identities = 68/212 (32%), Positives = 117/212 (55%), Gaps = 9/212 (4%) Query: 29 REAVRRGTTAIGIACKDGVVLAVDRRIT-SKLVKIRSIEKIFQIDDHVAAATSGLVADAR 87 + + GTT +GI KD V++A +RR+T + ++ +K+FQID + +GLV DA+ Sbjct: 2 NQTLETGTTTVGITLKDAVIMATERRVTMENFIMHKNGKKLFQIDTYTGMTIAGLVGDAQ 61 Query: 88 VLIDRARLEAQIYRLTYGEEISIEMLAKKICDIKQAYTQHGGVRPFGVSLLIAGIDKNEA 147 VL+ + E ++YRL + IE +A + ++ P+ V LL+ GID Sbjct: 62 VLVRYMKAELELYRLQRRVNMPIEAVATLLSNMLNQVKYM----PYMVQLLVGGID-TAP 116 Query: 148 RLFETDPSGALIEYKATAIGSGRPVVMELLEKEYRDDITLDEGLELAITALTKANEDIKP 207 +F D +G +E + GSG P V +LE +Y + +T+DEG++L I A++ A + Sbjct: 117 HVFSIDAAGGSVEDIYASTGSGSPFVYGVLESQYSEKMTVDEGVDLVIRAISAAKQRDSA 176 Query: 208 EN--VDVCIITVKDAQFKKIPVEEIKKLIEKV 237 +DV +IT KD + ++P ++I+ I K+ Sbjct: 177 SGGMIDVAVITRKDG-YVQLPTDQIESRIRKL 207 >3H4P-a nrPDB Length = 219 Score = 188 bits (478), Expect = 2e-48, Method: Composition-based stats. Identities = 66/207 (31%), Positives = 110/207 (53%), Gaps = 11/207 (5%) Query: 36 TTAIGIACKDGVVLAVDRRIT-SKLVKIRSIEKIFQIDDHVAAATSGLVADARVLIDRAR 94 TT +G+ C D V+LA D+R + LV + +K+++IDD++A +G V DA+ ++ Sbjct: 2 TTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIVRLLI 61 Query: 95 LEAQIYRLTYGEEISIEMLAKKICDIKQAYTQHGGVRPFGVSLLIAGIDK-NEARLFETD 153 EA++Y++ G I A + +I + PF ++I G D A+LF D Sbjct: 62 AEAKLYKMRTGRNIPPLACATLLSNILH----SSRMFPFLTQIIIGGYDLLEGAKLFSLD 117 Query: 154 PSGALIEYK-ATAIGSGRPVVMELLEKEYRDDITLDEGLELAITALTKANEDI--KPENV 210 P G + E K TA GSG P+ +LE Y D++++EG++LA+ AL A E + Sbjct: 118 PLGGMNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERDTFSGNGI 177 Query: 211 DVCIITVKDAQFKKIPVEEIKKLIEKV 237 + +IT K EEI+K+++ + Sbjct: 178 SLAVITK--DGVKIFEDEEIEKILDSM 202 >6HEC-1 nrPDB Length = 202 Score = 188 bits (477), Expect = 2e-48, Method: Composition-based stats. Identities = 62/206 (30%), Positives = 110/206 (53%), Gaps = 6/206 (2%) Query: 36 TTAIGIACKDGVVLAVDRRIT-SKLVKIRSIEKIFQIDDHVAAATSGLVADARVLIDRAR 94 TT +G+ CKDGVV+A ++R T + ++ +KI+QI D +A T+G V DA+ L + Sbjct: 1 TTTVGLVCKDGVVMATEKRATMGNFIASKAAKKIYQIADRMAMTTAGSVGDAQFLARIIK 60 Query: 95 LEAQIYRLTYGEEISIEMLAKKICDIKQAYTQHGGVRPFGVSLLIAGIDKNEARLFETDP 154 +EA +Y + + ++ +A ++ +Y P+ V LLI GID ++ DP Sbjct: 61 IEANLYEIRRERKPTVRAIATLTSNLLNSYRYF----PYLVQLLIGGIDSEGKSIYSIDP 116 Query: 155 SGALIEYK-ATAIGSGRPVVMELLEKEYRDDITLDEGLELAITALTKANEDIKPENVDVC 213 G IE K A GSG +LE + +I +DE +ELA+ A+ A + + Sbjct: 117 IGGAIEEKDIVATGSGSLTAYGVLEDRFTPEIGVDEAVELAVRAIYSAMKRDSASGDGID 176 Query: 214 IITVKDAQFKKIPVEEIKKLIEKVKK 239 ++ + + +F + EE+++++ K +K Sbjct: 177 VVKITEDEFYQYSPEEVEQILAKFRK 202 >6EPF-2 nrPDB Length = 277 Score = 186 bits (472), Expect = 9e-48, Method: Composition-based stats. Identities = 47/198 (23%), Positives = 87/198 (43%), Gaps = 8/198 (4%) Query: 30 EAVRRGTTAIGIACKDGVVLAVDRRITSKLV-KIRSIEKIFQIDDHVAAATSGLVADARV 88 +A + GTT G+ KDG+VL D R T +V ++ KI I ++ +G AD + Sbjct: 38 KARKTGTTIAGVVYKDGIVLGADTRATEGMVVADKNCSKIHFISPNIYCCGAGTAADTDM 97 Query: 89 LIDRARLEAQIYRLTYGEEISIEMLAKKICDIKQAYTQHGGVRPFGVSLLIAGIDKNEAR 148 +++ LT G + + + + Y + G +L++ G+D Sbjct: 98 TTQLISSNLELHSLTTGRLPRVVTANRMLKQMLFRYQGY-----IGAALVLGGVDVTGPH 152 Query: 149 LFETDPSGALIEYKATAIGSGRPVVMELLEKEYRDDITLDEGLELAITALTKA--NEDIK 206 L+ P G+ + +GSG M + E ++R D+ +E +L A+ N+ Sbjct: 153 LYSIYPHGSTDKLPYVTMGSGSLAAMAVFEDKFRPDMEEEEAKKLVSEAIAAGIFNDLGS 212 Query: 207 PENVDVCIITVKDAQFKK 224 N+D+C+I+ F + Sbjct: 213 GSNIDLCVISKSKLDFLR 230 >3UNH-H nrPDB Length = 234 Score = 185 bits (470), Expect = 2e-47, Method: Composition-based stats. Identities = 56/201 (27%), Positives = 99/201 (49%), Gaps = 8/201 (3%) Query: 36 TTAIGIACKDGVVLAVDRRITS-KLVKIRSIEKIFQIDDHVAAATSGLVADARVLIDRAR 94 TT G+ +DGV+L D R T+ +V +S EKI I + +G+ AD + A Sbjct: 1 TTIAGLVFRDGVILGADTRATNDSVVADKSCEKIHFIAPKIYCCGAGVAADTEMTTRMAA 60 Query: 95 LEAQIYRLTYGEEISIEMLAKKICDIKQAYTQHGGVRPFGVSLLIAGIDKNEARLFETDP 154 + +++ L+ G E + + + + Y H G SL++ G+D N +L+E P Sbjct: 61 SKMELHALSTGREPRVATVTRILRQTLFRYQGH-----VGASLVVGGVDLNGPQLYEVHP 115 Query: 155 SGALIEYKATAIGSGRPVVMELLEKEYRDDITLDEGLELAITALTKA--NEDIKPENVDV 212 G+ TA+GSG+ + LLE ++ ++TL+ EL + A+T ++ NVD Sbjct: 116 HGSYSRLPFTALGSGQGAAVALLEDRFQPNMTLEAAQELLVEAITAGILSDLGSGGNVDA 175 Query: 213 CIITVKDAQFKKIPVEEIKKL 233 C+IT A+ ++ + + Sbjct: 176 CVITAGGAKLQRALSTPTEPV 196 >6AVO-B nrPDB Length = 234 Score = 184 bits (467), Expect = 3e-47, Method: Composition-based stats. Identities = 52/201 (25%), Positives = 94/201 (46%), Gaps = 8/201 (3%) Query: 36 TTAIGIACKDGVVLAVDRRITS-KLVKIRSIEKIFQIDDHVAAATSGLVADARVLIDRAR 94 TT G+ +DGV+L D R T+ +V +S EKI I + +G+ ADA + Sbjct: 1 TTIAGLVFQDGVILGADTRATNDSVVADKSCEKIHFIAPKIYCCGAGVAADAEMTTRMVA 60 Query: 95 LEAQIYRLTYGEEISIEMLAKKICDIKQAYTQHGGVRPFGVSLLIAGIDKNEARLFETDP 154 + +++ L+ G E + + + + Y H G SL++ G+D +L+ P Sbjct: 61 SKMELHALSTGREPRVATVTRILRQTLFRYQGH-----VGASLIVGGVDLTGPQLYGVHP 115 Query: 155 SGALIEYKATAIGSGRPVVMELLEKEYRDDITLDEGLELAITALTKA--NEDIKPENVDV 212 G+ TA+GSG+ + +LE ++ ++TL+ L + A+T + NVD Sbjct: 116 HGSYSRLPFTALGSGQDAALAVLEDRFQPNMTLEAAQGLLVEAVTAGILGDLGSGGNVDA 175 Query: 213 CIITVKDAQFKKIPVEEIKKL 233 C+IT A+ + + + Sbjct: 176 CVITKTGAKLLRTLSSPTEPV 196 >5FGI-H nrPDB Length = 244 Score = 183 bits (464), Expect = 8e-47, Method: Composition-based stats. Identities = 51/199 (25%), Positives = 92/199 (46%), Gaps = 9/199 (4%) Query: 30 EAVRRGTTAIGIACKDGVVLAVDRRIT-SKLVKIRSIEKIFQIDDHVAAATSGLVADARV 88 +A G T +G+ +GVV+A D R T +V ++ K+ +I + A +G AD Sbjct: 7 KATSTGATIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEA 66 Query: 89 LIDRARLEAQIYRLTYGEEISIEMLAKKICDIKQAYTQHGGVRPFGVSLLIAGIDKNEAR 148 + +++ L E + + + Y H G L++AG+D + Sbjct: 67 VTQLIGSNIELHSLYTSREPRVVSALQMLKQHLFKYQGH-----IGAYLIVAGVDPTGSH 121 Query: 149 LFETDPSGALIEYKATAIGSGRPVVMELLEKEYRDDITLDEGLELAITALTKA--NEDIK 206 LF G+ ++GSG M +LE ++ D+T +E ++LA A+ N+ Sbjct: 122 LFSIHAHGSTDVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDLGS 181 Query: 207 PENVDVCIITV-KDAQFKK 224 NVDVC++ + KDA++ + Sbjct: 182 GSNVDVCVMEIGKDAEYLR 200 >5FMG-I nrPDB Length = 229 Score = 183 bits (464), Expect = 9e-47, Method: Composition-based stats. Identities = 52/197 (26%), Positives = 94/197 (47%), Gaps = 9/197 (4%) Query: 36 TTAIGIACKDGVVLAVDRRIT-SKLVKIRSIEKIFQIDDHVAAATSGLVADARVLIDRAR 94 TT G+ C++ V+L D R T +V ++ K+ I ++ A +G+ D + Sbjct: 1 TTICGLVCQNAVILGADTRATEGPIVADKNCSKLHYISKNIWCAGAGVAGDLEHTTLWLQ 60 Query: 95 LEAQIYRLTYGEEISIEMLAKKICDIKQAYTQHGGVRPFGVSLLIAGIDKNEARLFETDP 154 +++RL + + M ++ Y + ++++ G+D N +L+ P Sbjct: 61 HNVELHRLNTNTQPRVSMCVSRLTQELFKYQGYKV-----CAIVLGGVDVNGPQLYGIHP 115 Query: 155 SGALIEYKATAIGSGRPVVMELLEKEYRDDITLDEGLELAITALTKA--NEDIKPENVDV 212 G+ TA+GSG M +LE +YRD++T++EG L A+ N+ NVD+ Sbjct: 116 HGSSCLLPFTALGSGSLNAMAVLEAKYRDNMTIEEGKNLVCEAICAGIFNDLGSGGNVDI 175 Query: 213 CIITVKDAQFKKIPVEE 229 C+IT KD+ P +E Sbjct: 176 CVIT-KDSYQHIRPYKE 191 >6EPC-1 nrPDB Length = 238 Score = 182 bits (462), Expect = 1e-46, Method: Composition-based stats. Identities = 52/222 (23%), Positives = 90/222 (40%), Gaps = 11/222 (4%) Query: 16 FSPEGRLYQVEYAREAVRRGTTAIGIACKDGVVLAVDRRIT-SKLVKIRSIEKIFQIDDH 74 F PE ++ V GTT + + GVVL D R T + R +K+ I DH Sbjct: 16 FGPEA--LTPDWENREVSTGTTIMAVQFDGGVVLGADSRTTTGSYIANRVTDKLTPIHDH 73 Query: 75 VAAATSGLVADARVLIDRARLEAQIYRLTYGEEISIEMLAKKICDIKQAYTQHGGVRPFG 134 + SG AD + + D + + + E + A ++ Y + Sbjct: 74 IFCCRSGSAADTQAVADAVTYQLGFHSIELNEPPLVHTAASLFKEMCYRYRED-----LM 128 Query: 135 VSLLIAGIDKNEARLFETDPSGALIEYKATAI-GSGRPVVMELLEKEYRDDITLDEGLEL 193 ++IAG D E + P G ++ ++ AI GSG + ++ YR+ +T DE L+ Sbjct: 129 AGIIIAGWDPQEGGQVYSVPMGGMMVRQSFAIGGSGSSYIYGYVDATYREGMTKDECLQF 188 Query: 194 AITALTKANEDIKPEN--VDVCIITVKDAQFKKIPVEEIKKL 233 AL A E + + I + + + ++I K+ Sbjct: 189 TANALALAMERDGSSGGVIRLAAIQQSGVERQVLLGDQIPKV 230 >5GJQ-a nrPDB Length = 239 Score = 181 bits (460), Expect = 3e-46, Method: Composition-based stats. Identities = 49/222 (22%), Positives = 89/222 (40%), Gaps = 11/222 (4%) Query: 16 FSPEGRLYQVEYAREAVRRGTTAIGIACKDGVVLAVDRRIT-SKLVKIRSIEKIFQIDDH 74 + PE + ++ V GTT + + GVVL D R T + R +K+ I D Sbjct: 17 WGPEA--FTPDWESREVSTGTTIMAVQFDGGVVLGADSRTTTGSYIANRVTDKLTPIHDR 74 Query: 75 VAAATSGLVADARVLIDRARLEAQIYRLTYGEEISIEMLAKKICDIKQAYTQHGGVRPFG 134 + SG AD + + D + + + E + A ++ Y + Sbjct: 75 IFCCRSGSAADTQAVADAVTYQLGFHSIELNEPPLVHTAASLFKEMCYRYRED-----LM 129 Query: 135 VSLLIAGIDKNEARLFETDPSGALIEYKATAI-GSGRPVVMELLEKEYRDDITLDEGLEL 193 ++IAG D E + P G ++ ++ AI GSG + ++ YR+ +T +E L+ Sbjct: 130 AGIIIAGWDPQEGGQVYSVPMGGMMVRQSFAIGGSGSSYIYGYVDATYREGMTKEECLQF 189 Query: 194 AITALTKANEDIKPEN--VDVCIITVKDAQFKKIPVEEIKKL 233 AL A E + + I + + + ++I K Sbjct: 190 TANALALAMERDGSSGGVIRLAAIAESGVERQVLLGDQIPKF 231 >5L4G-8 nrPDB Length = 277 Score = 181 bits (459), Expect = 3e-46, Method: Composition-based stats. Identities = 45/198 (22%), Positives = 85/198 (42%), Gaps = 8/198 (4%) Query: 30 EAVRRGTTAIGIACKDGVVLAVDRRITSKLV-KIRSIEKIFQIDDHVAAATSGLVADARV 88 + + GTT G+ KDG+VL D R T +V ++ KI I ++ +G AD + Sbjct: 38 KVRKTGTTIAGVVYKDGIVLGADTRATEGMVVADKNCSKIHFISPNIYCCGAGTAADTDM 97 Query: 89 LIDRARLEAQIYRLTYGEEISIEMLAKKICDIKQAYTQHGGVRPFGVSLLIAGIDKNEAR 148 +++ L+ G + + + + Y + G +L++ G+D Sbjct: 98 TTQLISSNLELHSLSTGRLPRVVTANRMLKQMLFRYQGY-----IGAALVLGGVDVTGPH 152 Query: 149 LFETDPSGALIEYKATAIGSGRPVVMELLEKEYRDDITLDEGLELAITALTKA--NEDIK 206 L+ P G+ + +GSG M + E ++R D+ +E L A+ N+ Sbjct: 153 LYSIYPHGSTDKLPYVTMGSGSLAAMAVFEDKFRPDMEEEEAKNLVSEAIAAGIFNDLGS 212 Query: 207 PENVDVCIITVKDAQFKK 224 N+D+C+I+ F + Sbjct: 213 GSNIDLCVISKNKLDFLR 230 >6HV7-H nrPDB Length = 226 Score = 175 bits (444), Expect = 2e-44, Method: Composition-based stats. Identities = 53/193 (27%), Positives = 91/193 (47%), Gaps = 9/193 (4%) Query: 36 TTAIGIACKDGVVLAVDRRITS-KLVKIRSIEKIFQIDDHVAAATSGLVADARVLIDRAR 94 TT G+ +DGV+L D R T+ +V +S EKI I + +G+ ADA + Sbjct: 1 TTIAGLVFQDGVILGADTRATNDSVVADKSCEKIHFIAPKIYCCGAGVAADAEAVTQLIG 60 Query: 95 LEAQIYRLTYGEEISIEMLAKKICDIKQAYTQHGGVRPFGVSLLIAGIDKNEARLFETDP 154 +++ L E + + + Y H G L++AG+D + LF Sbjct: 61 SNIELHSLYTSREPRVVSALQMLKQHLFKYQGH-----IGAYLIVAGVDPTGSHLFSIHA 115 Query: 155 SGALIEYKATAIGSGRPVVMELLEKEYRDDITLDEGLELAITALTKA--NEDIKPENVDV 212 G+ ++GSG M +LE ++ D+T +E ++LA A+ N+ NVDV Sbjct: 116 HGSTDVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDLGSGSNVDV 175 Query: 213 CIITV-KDAQFKK 224 C++ + KDA++ + Sbjct: 176 CVMEIGKDAEYLR 188 >6HUB-H nrPDB Length = 234 Score = 174 bits (442), Expect = 3e-44, Method: Composition-based stats. Identities = 44/192 (22%), Positives = 82/192 (42%), Gaps = 8/192 (4%) Query: 36 TTAIGIACKDGVVLAVDRRITSKLV-KIRSIEKIFQIDDHVAAATSGLVADARVLIDRAR 94 TT G+ KDG+VL D R T +V ++ KI I ++ +G AD + Sbjct: 1 TTIAGVVYKDGIVLGADTRATEGMVVADKNCSKIHFISPNIYCCGAGTAADTDMTTQLIS 60 Query: 95 LEAQIYRLTYGEEISIEMLAKKICDIKQAYTQHGGVRPFGVSLLIAGIDKNEARLFETDP 154 +++ L+ G + + + + Y + G +L++ G+D L+ P Sbjct: 61 SNLELHSLSTGRLPRVVTANRMLKQMLFRYQGY-----IGAALVLGGVDVTGPHLYSIYP 115 Query: 155 SGALIEYKATAIGSGRPVVMELLEKEYRDDITLDEGLELAITALTKA--NEDIKPENVDV 212 G+ + +GSG M + E ++R D+ +E L A+ N+ N+D+ Sbjct: 116 HGSTDKLPYVTMGSGSLAAMAVFEDKFRPDMEEEEAKNLVSEAIAAGIFNDLGSGGNIDL 175 Query: 213 CIITVKDAQFKK 224 C+I+ F + Sbjct: 176 CVISKNKLDFLR 187 >5FMG-L nrPDB Length = 211 Score = 174 bits (442), Expect = 3e-44, Method: Composition-based stats. Identities = 50/212 (23%), Positives = 92/212 (43%), Gaps = 6/212 (2%) Query: 36 TTAIGIACKDGVVLAVDRRIT-SKLVKIRSIEKIFQIDDHVAAATSGLVADARVLIDRAR 94 TT + KDG+++AVD R + + +++EKI +I+ ++ +G AD Sbjct: 1 TTTLAFKFKDGIIVAVDSRASMGSFISSQNVEKIIEINKNILGTMAGGAADCLYWEKYLG 60 Query: 95 LEAQIYRLTYGEEISIEMLAKKICDIKQAYTQHGGVRPFGVSLLIAGIDKNEARLFETDP 154 +IY L E+IS+ + + +I Y +G ++++G D +F D Sbjct: 61 KIIKIYELRNNEKISVRAASTILSNILYQYKGYG----LCCGIILSGYDHTGFNMFYVDD 116 Query: 155 SGALIEYKATAIGSGRPVVMELLEKEYRDDITLDEGLELAITALTKANEDIKPENVDVCI 214 SG +E + GSG +L+ Y ++ LD+ +ELA A+ A V + Sbjct: 117 SGKKVEGNLFSCGSGSTYAYSILDSAYDYNLNLDQAVELARNAIYHATFRDGGSGGKVRV 176 Query: 215 ITV-KDAQFKKIPVEEIKKLIEKVKKKLNEEN 245 + K+ K I E++ L ++ Sbjct: 177 FHIHKNGYDKIIEGEDVFDLHYHYTNPEQKDQ 208 >5LEZ-N nrPDB Length = 205 Score = 165 bits (419), Expect = 1e-41, Method: Composition-based stats. Identities = 45/202 (22%), Positives = 81/202 (40%), Gaps = 9/202 (4%) Query: 36 TTAIGIACKDGVVLAVDRRIT-SKLVKIRSIEKIFQIDDHVAAATSGLVADARVLIDRAR 94 TT + + GVVL D R T + R +K+ I D + SG AD + + D Sbjct: 1 TTIMAVQFDGGVVLGADSRTTTGSYIANRVTDKLTPIHDRIFCCRSGSAADTQAVADAVT 60 Query: 95 LEAQIYRLTYGEEISIEMLAKKICDIKQAYTQHGGVRPFGVSLLIAGIDKNEARLFETDP 154 + + + E + A ++ Y + ++IAG D E + P Sbjct: 61 YQLGFHSIELNEPPLVHTAASLFKEMCYRYRED-----LMAGIIIAGWDPQEGGQVYSVP 115 Query: 155 SGALIEYKATAI-GSGRPVVMELLEKEYRDDITLDEGLELAITALTKANEDIKPEN--VD 211 G ++ ++ AI GSG + ++ YR+ +T +E L+ AL A E + Sbjct: 116 MGGMMVRQSFAIGGSGSSYIYGYVDATYREGMTKEECLQFTANALALAMERDGSSGGVIR 175 Query: 212 VCIITVKDAQFKKIPVEEIKKL 233 + I + + + ++I K Sbjct: 176 LAAIAESGVERQVLLGDQIPKF 197 >6AVO-A nrPDB Length = 199 Score = 160 bits (406), Expect = 5e-40, Method: Composition-based stats. Identities = 40/204 (19%), Positives = 81/204 (39%), Gaps = 8/204 (3%) Query: 36 TTAIGIACKDGVVLAVDRRIT-SKLVKIRSIEKIFQIDDHVAAATSGLVADARVLIDRAR 94 TT + + GVV+ D R++ + V R +K+ + + + A SG ADA+ + D A Sbjct: 1 TTIMAVEFDGGVVMGSDSRVSAGEAVVNRVFDKLSPLHERIYCALSGSAADAQAVADMAA 60 Query: 95 LEAQIYRLTYGEEISIEMLAKKICDIKQAYTQHGGVRPFGVSLLIAGIDKNEARLFETDP 154 + +++ + E + A + +I Y + L++AG D+ E Sbjct: 61 YQLELHGIELEEPPLVLAAANVVRNISYKYRED-----LSAHLMVAGWDQREGGQVYGTL 115 Query: 155 SGALIEYKATAIGSGRPVVMELLEKEYRDDITLDEGLELAITALTKANEDIKPENVDVCI 214 G L GSG + ++ Y+ ++ +E A+ A + + Sbjct: 116 GGMLTRQPFAIGGSGSTFIYGYVDAAYKPGMSPEECRRFTTDAIALAMSRDGSSGGVIYL 175 Query: 215 ITVK--DAQFKKIPVEEIKKLIEK 236 +T+ + I E+ K ++ Sbjct: 176 VTITAAGVDHRVILGNELPKFYDE 199 >3UNF-N nrPDB Length = 199 Score = 154 bits (389), Expect = 4e-38, Method: Composition-based stats. Identities = 45/204 (22%), Positives = 84/204 (41%), Gaps = 8/204 (3%) Query: 36 TTAIGIACKDGVVLAVDRRITSKL-VKIRSIEKIFQIDDHVAAATSGLVADARVLIDRAR 94 TT + + GVV+ D R+++ V R +K+ + + A SG ADA+ + D A Sbjct: 1 TTIMAVEFDGGVVVGSDSRVSAGTAVVNRVFDKLSPLHQRIFCALSGSAADAQAIADMAA 60 Query: 95 LEAQIYRLTYGEEISIEMLAKKICDIKQAYTQHGGVRPFGVSLLIAGIDKNEARLFETDP 154 + +++ L E + A + +I Y + L++AG D+ E Sbjct: 61 YQLELHGLELEEPPLVLAAANVVKNISYKYRED-----LLAHLIVAGWDQREGGQVYGTM 115 Query: 155 SGALIEYKATAIGSGRPVVMELLEKEYRDDITLDEGLELAITALTKANEDIKPENVDVCI 214 G LI T GSG + ++ Y+ +T +E A+T A + + Sbjct: 116 GGMLIRQPFTIGGSGSSYIYGYVDAAYKPGMTPEECRRFTTNAITLAMNRDGSSGGVIYL 175 Query: 215 ITVK--DAQFKKIPVEEIKKLIEK 236 +T+ + I +E+ K ++ Sbjct: 176 VTITAAGVDHRVILGDELPKFYDE 199 >5MPC-h nrPDB Length = 215 Score = 148 bits (375), Expect = 1e-36, Method: Composition-based stats. Identities = 42/207 (20%), Positives = 90/207 (43%), Gaps = 10/207 (4%) Query: 31 AVRRGTTAIGIACKDGVVLAVDRRIT-SKLVKIRSIEKIFQIDDHVAAATSGLVADARVL 89 V GT+ + + KDGV+L D R T + R +K+ ++ D + SG AD + + Sbjct: 15 EVSLGTSIMAVTFKDGVILGADSRTTTGAYIANRVTDKLTRVHDKIWCCRSGSAADTQAI 74 Query: 90 IDRARLEAQIYRLTYGEEISIEMLAKKICDIKQAYTQHGGVRPFGVSLLIAGID-KNEAR 148 D + ++Y YG S E A ++ + +++AG D KN+ Sbjct: 75 ADIVQYHLELYTSQYGTP-STETAASVFKELCYENKDN-----LTAGIIVAGYDDKNKGE 128 Query: 149 LFETDPSGALIEYKATAIGSGRPVVMELLEKEYRDDITLDEGLELAITALTKANEDIKPE 208 ++ G++ + GSG + +K +R++++ +E ++ +L++A + Sbjct: 129 VYTIPLGGSVHKLPYAIAGSGSTFIYGYCDKNFRENMSKEETVDFIKHSLSQAIKWDGSS 188 Query: 209 NVDV--CIITVKDAQFKKIPVEEIKKL 233 + ++T + +E ++L Sbjct: 189 GGVIRMVVLTAAGVERLIFYPDEYEQL 215 >5FMG-M nrPDB Length = 240 Score = 144 bits (363), Expect = 4e-35, Method: Composition-based stats. Identities = 49/207 (23%), Positives = 93/207 (44%), Gaps = 16/207 (7%) Query: 19 EGRLYQVEYAREAVRRGTTAIGIACKDGVVLAVDRRIT-SKLVKIRSIEKIFQIDDHVAA 77 GR ++ Y + G T IG+ KD V+LA D R++ S + R KI ++ D Sbjct: 23 HGRGFKRWYPY--IDNGGTVIGLTGKDYVILAADTRLSLSYSIYTRFCPKISKLTDKCII 80 Query: 78 ATSGLVADARVLIDRARLEAQIYRLTYGEEISIEMLAKKICDIKQAYTQHGGVRPFGVSL 137 +SG+ +D + L + + Q++ L + I ++A+ +C I Y++ P+ Sbjct: 81 GSSGMQSDIKTLHSLLQKKIQLFVLEHSHYPDIHVIARLLCVIL--YSRR--FFPYYAFN 136 Query: 138 LIAGIDK-NEARLFETDPSGALIEYKATAIGSGRPVVMELLEKEYRD--------DITLD 188 ++AG+D+ N+ L+ D G+ E + +GSG +++ +L+ + L Sbjct: 137 ILAGVDENNKGVLYNYDSVGSYCEATHSCVGSGSQLILPILDNRVEQKNQLIKNTNFNLG 196 Query: 189 EGLELAITALTKANEDIKPENVDVCII 215 + + A+T A E I Sbjct: 197 DDINFVKDAITSATERDIYTGDKTLIY 223 >5FGE-J nrPDB Length = 198 Score = 138 bits (348), Expect = 2e-33, Method: Composition-based stats. Identities = 44/193 (22%), Positives = 86/193 (44%), Gaps = 5/193 (2%) Query: 38 AIGIACKDGVVLAVDRRITSKLVKIR-SIEKIFQIDDHVAAATSGLVADARVLIDRARLE 96 +GI +D V+LA + +T + ++ S +K Q+ H + +G D + + Sbjct: 4 ILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQAN 63 Query: 97 AQIYRLTYGEEISIEMLAKKICDIKQAYTQHGGVRPFGVSLLIAGIDK--NEARLFETDP 154 Q+Y + E+S + ++ + + RP+ V++LI G DK N+ L++ D Sbjct: 64 IQLYSIREDYELSPQAVSSFVRQELAKSIRS--RRPYQVNVLIGGYDKKKNKPELYQIDY 121 Query: 155 SGALIEYKATAIGSGRPVVMELLEKEYRDDITLDEGLELAITALTKANEDIKPENVDVCI 214 G +E A G LL+ YR D+T +EGL+L + + + + + V + Sbjct: 122 LGTKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQELEKRMPMDFKGVIV 181 Query: 215 ITVKDAQFKKIPV 227 V +++ Sbjct: 182 KIVDKDGIRQVDD 194 >3WXR-K nrPDB Length = 238 Score = 137 bits (346), Expect = 3e-33, Method: Composition-based stats. Identities = 44/193 (22%), Positives = 86/193 (44%), Gaps = 5/193 (2%) Query: 38 AIGIACKDGVVLAVDRRITSKLVKIR-SIEKIFQIDDHVAAATSGLVADARVLIDRARLE 96 +GI +D V+LA + +T + ++ S +K Q+ H + +G D + + Sbjct: 4 ILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQAN 63 Query: 97 AQIYRLTYGEEISIEMLAKKICDIKQAYTQHGGVRPFGVSLLIAGIDK--NEARLFETDP 154 Q+Y + E+S + ++ + + RP+ V++LI G DK N+ L++ D Sbjct: 64 IQLYSIREDYELSPQAVSSFVRQELAKSIRS--RRPYQVNVLIGGYDKKKNKPELYQIDY 121 Query: 155 SGALIEYKATAIGSGRPVVMELLEKEYRDDITLDEGLELAITALTKANEDIKPENVDVCI 214 G +E A G LL+ YR D+T +EGL+L + + + + + V + Sbjct: 122 LGTKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQELEKRMPMDFKGVIV 181 Query: 215 ITVKDAQFKKIPV 227 V +++ Sbjct: 182 KIVDKDGIRQVDD 194 >1Q5R-H nrPDB Length = 294 Score = 137 bits (345), Expect = 5e-33, Method: Composition-based stats. Identities = 55/226 (24%), Positives = 94/226 (41%), Gaps = 15/226 (6%) Query: 34 RGTTAIGIACKDGVVLAVDRRIT-SKLVKIRSIEKIFQIDDHVAAATSGLVADARVLIDR 92 GTT + + K GV+LA DRR T L+ R +E ++ D++ AA +G A L+ Sbjct: 64 HGTTIVALTYKGGVLLAGDRRATQGNLIASRDVEAVYVTDEYSAAGIAGTAGIAIELVRL 123 Query: 93 ARLEAQIYRLTYGEEISIEMLAKKICDIKQ----AYTQHGGVRPFGVSLLIAGIDKNE-A 147 +E + Y G ++ + A ++ + + A Q V P V + D++ Sbjct: 124 FAVELEHYEKIEGVPLTFDGKANRLASMVRGNLGAAMQGLAVVPLLVGYDLDADDESRAG 183 Query: 148 RLFETDPSGALIEYKAT--AIGSGRPVVMELLEKEYRDDITLDEGLELAITALTKANEDI 205 R+ D G E +A A+GSG L+K Y D + L AI +L A +D Sbjct: 184 RIVSYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDSDEETALRAAIESLYDAADDD 243 Query: 206 KPE-------NVDVCIITVKDAQFKKIPVEEIKKLIEKVKKKLNEE 244 + +T+ A + E +L ++ + E+ Sbjct: 244 SATGGPDLTRGIYPTAVTITQAGAVHVSEETTSELARRIVAERTEQ 289 >1Q5Q-H nrPDB Length = 235 Score = 133 bits (336), Expect = 5e-32, Method: Composition-based stats. Identities = 55/224 (24%), Positives = 94/224 (41%), Gaps = 15/224 (6%) Query: 36 TTAIGIACKDGVVLAVDRRIT-SKLVKIRSIEKIFQIDDHVAAATSGLVADARVLIDRAR 94 TT + + K GV+LA DRR T L+ R +EK++ D++ AA +G A L+ Sbjct: 1 TTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAGTAGIAIELVRLFA 60 Query: 95 LEAQIYRLTYGEEISIEMLAKKICDIKQ----AYTQHGGVRPFGVSLLIAGIDKNE-ARL 149 +E + Y G ++ + A ++ + + A Q V P V + D++ R+ Sbjct: 61 VELEHYEKIEGVPLTFDGKANRLASMVRGNLGAAMQGLAVVPLLVGYDLDADDESRAGRI 120 Query: 150 FETDPSGALIEYKAT--AIGSGRPVVMELLEKEYRDDITLDEGLELAITALTKANEDIKP 207 D G E +A A+GSG L+K Y D + L AI +L A +D Sbjct: 121 VSYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDSDEETALRAAIESLYDAADDDSA 180 Query: 208 E-------NVDVCIITVKDAQFKKIPVEEIKKLIEKVKKKLNEE 244 + +T+ A + E +L ++ + E+ Sbjct: 181 TGGPDLTRGIYPTAVTITQAGAVHVSEETTSELARRIVAERTEQ 224 >5FMG-K nrPDB Length = 195 Score = 131 bits (330), Expect = 2e-31, Method: Composition-based stats. Identities = 40/161 (24%), Positives = 72/161 (44%), Gaps = 8/161 (4%) Query: 37 TAIGIACKDGVVLAVDRRITSKLVKIRSIE--KIFQIDDHVAAATSGLVADARVLIDRAR 94 T IG+ + VVLA D + ++K+++ + K + I + G + D + R Sbjct: 3 TLIGLRGNNFVVLAADTYSINSIIKLKNDDNTKFYDIHGNKCLLLGGSIGDRLQFGEFIR 62 Query: 95 LEAQIYRLTYGEEISIEMLAKKICDIKQAYTQHGGVR-PFGVSLLIAGIDKNEA-RLFET 152 +Y+ +M K + + R PF V+ LIAG DK + +L+ Sbjct: 63 KNVHLYQYQNNT----DMFVKSFAFFTRKNLAYYLRRNPFEVNCLIAGYDKKDGYQLYWC 118 Query: 153 DPSGALIEYKATAIGSGRPVVMELLEKEYRDDITLDEGLEL 193 D + A G G +V +L+K Y +++T+DE L++ Sbjct: 119 DYLSNMDSVNKGAHGYGAYLVSAILDKYYHENLTVDEALDI 159 >2JAY-A nrPDB Length = 291 Score = 125 bits (314), Expect = 2e-29, Method: Composition-based stats. Identities = 48/185 (25%), Positives = 71/185 (38%), Gaps = 8/185 (4%) Query: 34 RGTTAIGIACKDGVVLAVDRRIT-SKLVKIRSIEKIFQIDDHVAAATSGLVADARVLIDR 92 GTT + + GVV+A DRR T ++ R + K++ DD+ A +G A A Sbjct: 56 HGTTIVALKYPGGVVMAGDRRSTQGNMISGRDVRKVYITDDYTATGIAGTAAVAVEFARL 115 Query: 93 ARLEAQIYRLTYGEEIS----IEMLAKKICDIKQAYTQHGGVRPFGVSLLIAGIDKNE-A 147 +E + Y G ++ I LA + A Q P I D Sbjct: 116 YAVELEHYEKLEGVPLTFAGKINRLAIMVRGNLAAAMQGLLALPLLAGYDIHASDPQSAG 175 Query: 148 RLFETDPSGALI--EYKATAIGSGRPVVMELLEKEYRDDITLDEGLELAITALTKANEDI 205 R+ D +G E A+GSG ++K Y D GL +A+ AL A +D Sbjct: 176 RIVSFDAAGGWNIEEEGYQAVGSGSLFAKSSMKKLYSQVTDGDSGLRVAVEALYDAADDD 235 Query: 206 KPENV 210 Sbjct: 236 SATGG 240 >3NZW-L nrPDB Length = 241 Score = 125 bits (314), Expect = 2e-29, Method: Composition-based stats. Identities = 52/228 (22%), Positives = 96/228 (42%), Gaps = 38/228 (16%) Query: 26 EYAREAVR------------RGTTAIGIACKDGVVLAVDRR-ITSKLVKIRSIEKIFQID 72 EY+ EA G T +GIA +D VLA D R IT + R K+F Sbjct: 7 EYSSEASNTPIEHQFNPYGDNGGTILGIAGEDFAVLAGDTRNITDYSINSRYEPKVFDCG 66 Query: 73 DHVAAATSGLVADARVLIDRARLEAQIYRLTYGE-EISIEMLAKKICDIKQAYTQHGGVR 131 D++ + +G AD L+ R + + Y + + ++SI A+ I + Sbjct: 67 DNIVMSANGFAADGDALVKRFKNSVKWYHFDHNDKKLSINSAARNIQHLLY----GKRFF 122 Query: 132 PFGVSLLIAGIDKNE-ARLFETDPSGALIEYKATAIGSGRPVVMELLE------KEYRDD 184 P+ V +IAG+D++ ++ DP G+ + A G+ ++M L+ +Y Sbjct: 123 PYYVHTIIAGLDEDGKGAVYSFDPVGSYEREQCRAGGAAASLIMPFLDNQVNFKNQYEPG 182 Query: 185 -----------ITLDEGLELAITALTKANED--IKPENVDVCIITVKD 219 ++++E ++L + T A E + +++ I+T Sbjct: 183 TNGKVKKPLKYLSVEEVIKLVRDSFTSATERHIQVGDGLEILIVTKDG 230 >5LF3-J nrPDB Length = 201 Score = 123 bits (310), Expect = 6e-29, Method: Composition-based stats. Identities = 42/173 (24%), Positives = 81/173 (46%), Gaps = 12/173 (6%) Query: 39 IGIACKDGVVLAVDRRITSKLVKIRS-IEKIFQIDDHVAAATSGLVADARVLIDRARLEA 97 IGI D V++A DR S +V+++ +K+F++ + + G D + + Sbjct: 5 IGIQGPDYVLVASDRVAASNIVQMKDDHDKMFKMSEKILLLCVGEAGDTVQFAEYIQKNV 64 Query: 98 QIYRLTYGEEISIEMLA----KKICDIKQAYTQHGGVRPFGVSLLIAGIDKN-EARLFET 152 Q+Y++ G E+S A + + D ++ T P+ V+LL+AG D++ L+ Sbjct: 65 QLYKMRNGYELSPTAAANFTRRNLADCLRSRT------PYHVNLLLAGYDEHEGPALYYM 118 Query: 153 DPSGALIEYKATAIGSGRPVVMELLEKEYRDDITLDEGLELAITALTKANEDI 205 D AL + A G G + + +L++ Y I+ + +EL L + + Sbjct: 119 DYLAALAKAPFAAHGYGAFLTLSILDRYYTPTISRERAVELLRKCLEELQKRF 171 >3UNE-I nrPDB Length = 205 Score = 121 bits (304), Expect = 3e-28, Method: Composition-based stats. Identities = 38/195 (19%), Positives = 78/195 (40%), Gaps = 10/195 (5%) Query: 34 RGTTAIGIACKDGVVLAVDRR--ITSKLVKIRSIEKIFQIDDHVAAATSGLVADARVLID 91 G + + K+ V +A DRR I +++V +KIF + D + +GL D + + Sbjct: 7 NGGAVMAMKGKNCVAIAADRRFGIQAQMV-TTDFQKIFPMGDRLYIGLAGLATDVQTVAQ 65 Query: 92 RARLEAQIYRLTYGEEISIEMLAKKICDIKQAYTQHGGVRPFGVSLLIAGIDKNEARLF- 150 R + +Y L G +I L + ++ Y + G P+ +IAG+D + F Sbjct: 66 RLKFRLNLYELKEGRQIKPYTLMSMVANLL--YEKRFG--PYYTEPVIAGLDPKTFKPFI 121 Query: 151 -ETDPSGA-LIEYKATAIGSGRPVVMELLEKEYRDDITLDEGLELAITALTKANEDIKPE 208 D G ++ G+ + + E + ++ + E A+ A + Sbjct: 122 CSLDLIGCPMVTDDFVVSGTCSEQMYGMCESLWEPNMDPEHLFETISQAMLNAVDRDAVS 181 Query: 209 NVDVCIITVKDAQFK 223 + V + ++ + Sbjct: 182 GMGVIVHVIEKDKIT 196 >6EPE-7 nrPDB Length = 263 Score = 120 bits (301), Expect = 6e-28, Method: Composition-based stats. Identities = 44/196 (22%), Positives = 74/196 (37%), Gaps = 10/196 (5%) Query: 34 RGTTAIGIACKDGVVLAVDRRIT-SKLVKIRSIEKIFQIDDHVAAATSGLVADARVLIDR 92 GT+ +G+ GVV+A D + L + R+I +I +++D SG AD + L Sbjct: 51 TGTSVLGVKFDCGVVIAADMLGSYGSLARFRNISRIMRVNDSTMLGASGDYADFQYLKQV 110 Query: 93 ARLEAQIYRLTYGEEISIEMLAKKICDIKQAYTQHGGVRPFGVSLLIAGIDKNEARLFET 152 L +G+ S A + Y++ + P + +I G E+ L Sbjct: 111 LGQMVIDEEL-FGDGHSYSPRAIHSWLTRAMYSRRSKMNPLWNTKVIGGYAGGESFLGYV 169 Query: 153 DPSGALIEYKATAIGSGRPVV----MELLEKEYRDDITLDEGLELAITALTKANEDI--K 206 D G E + A G G + E+LEK+ ++ E EL + Sbjct: 170 DMLGVAYEAPSLATGYGAYLAQPLLREVLEKQ--PVLSQTEARELVERCMRVLYYRDARS 227 Query: 207 PENVDVCIITVKDAQF 222 V +T K + Sbjct: 228 YNRFQVATVTEKGVEI 243 >4Y8P-I nrPDB Length = 205 Score = 120 bits (301), Expect = 7e-28, Method: Composition-based stats. Identities = 47/197 (23%), Positives = 79/197 (40%), Gaps = 10/197 (5%) Query: 34 RGTTAIGIACKDGVVLAVDRRITSKLVKIRS-IEKIFQIDDHVAAATSGLVADARVLIDR 92 G + + KD V +A D R+ S+ + + + EKIF HV +GL D L + Sbjct: 8 NGGIVVAMTGKDCVAIACDLRLGSQSLGVSNKFEKIFHYG-HVFLGITGLATDVTTLNEM 66 Query: 93 ARLEAQIYRLTYGEEISIEMLAKKICDIKQAYTQHGGVRPFGVSLLIAGIDKNEARLF-- 150 R + +Y+L I E + + Y + G P+ V ++AGI+ + F Sbjct: 67 FRYKTNLYKLKEERAIEPETFTQLVSS--SLYERRFG--PYFVGPVVAGINSKSGKPFIA 122 Query: 151 ETDPSGALIEYKATAI-GSGRPVVMELLEKEYRDDITLDEGLELAITALTKANEDIKPEN 209 D G + E K + G+ + + E Y ++ ++ E AL A + Sbjct: 123 GFDLIGCIDEAKDFIVSGTASDQLFGMCESLYEPNLEPEDLFETISQALLNAADRDALSG 182 Query: 210 -VDVCIITVKDAQFKKI 225 V I KD K+ Sbjct: 183 WGAVVYIIKKDEVVKRY 199 >5GJQ-g nrPDB Length = 264 Score = 120 bits (300), Expect = 8e-28, Method: Composition-based stats. Identities = 41/196 (20%), Positives = 75/196 (38%), Gaps = 10/196 (5%) Query: 34 RGTTAIGIACKDGVVLAVDRRIT-SKLVKIRSIEKIFQIDDHVAAATSGLVADARVLIDR 92 GT+ +G+ + GVV+A D + L + R+I +I ++++ SG AD + L Sbjct: 52 TGTSVLGVKFEGGVVIAADMLGSYGSLARFRNISRIMRVNNSTMLGASGDYADFQYLKQV 111 Query: 93 ARLEAQIYRLTYGEEISIEMLAKKICDIKQAYTQHGGVRPFGVSLLIAGIDKNEARLFET 152 L G+ S A + Y++ + P +++I G E+ L Sbjct: 112 LGQMVIDEELL-GDGHSYSPRAIHSWLTRAMYSRRSKMNPLWNTMVIGGYADGESFLGYV 170 Query: 153 DPSGALIEYKATAIGSGRPVV----MELLEKEYRDDITLDEGLELAITALTKANEDI--K 206 D G E + A G G + E+LEK+ ++ E +L + Sbjct: 171 DMLGVAYEAPSLATGYGAYLAQPLLREVLEKQ--PVLSQTEARDLVERCMRVLYYRDARS 228 Query: 207 PENVDVCIITVKDAQF 222 + +T K + Sbjct: 229 YNRFQIATVTEKGVEI 244 >5LF6-M nrPDB Length = 219 Score = 118 bits (297), Expect = 2e-27, Method: Composition-based stats. Identities = 41/196 (20%), Positives = 75/196 (38%), Gaps = 10/196 (5%) Query: 34 RGTTAIGIACKDGVVLAVDRRIT-SKLVKIRSIEKIFQIDDHVAAATSGLVADARVLIDR 92 GT+ +G+ + GVV+A D + L + R+I +I ++++ SG AD + L Sbjct: 7 TGTSVLGVKFEGGVVIAADMLGSYGSLARFRNISRIMRVNNSTMLGASGDYADFQYLKQV 66 Query: 93 ARLEAQIYRLTYGEEISIEMLAKKICDIKQAYTQHGGVRPFGVSLLIAGIDKNEARLFET 152 L G+ S A + Y++ + P +++I G E+ L Sbjct: 67 LGQMVIDEELL-GDGHSYSPRAIHSWLTRAMYSRRSKMNPLWNTMVIGGYADGESFLGYV 125 Query: 153 DPSGALIEYKATAIGSGRPVV----MELLEKEYRDDITLDEGLELAITALTKANEDI--K 206 D G E + A G G + E+LEK+ ++ E +L + Sbjct: 126 DMLGVAYEAPSLATGYGAYLAQPLLREVLEKQ--PVLSQTEARDLVERCMRVLYYRDARS 183 Query: 207 PENVDVCIITVKDAQF 222 + +T K + Sbjct: 184 YNRFQIATVTEKGVEI 199 >5L4G-U nrPDB Length = 241 Score = 117 bits (294), Expect = 4e-27, Method: Composition-based stats. Identities = 41/201 (20%), Positives = 81/201 (40%), Gaps = 17/201 (8%) Query: 32 VRRGTTAIGIACKDGVVLAVDRRITSKL-VKIRSIEKIFQIDDHVAAATSGLVADARVLI 90 V G T + IA +D ++A D R++ + R K +++ D SG D L Sbjct: 34 VFNGGTILAIAGEDFAIVASDTRLSEGFSIHTRDSPKCYKLTDKTVIGCSGFHGDCLTLT 93 Query: 91 DRARLEAQIYRLTYGEEISIEMLAKKICDIKQAYTQHGGVRPFGVSLLIAGIDKNE-ARL 149 ++Y+ + + ++ +A + I Y++ P+ V +I G+D+ + Sbjct: 94 KIIEARLKMYKHSNNKAMTTGAIAAMLSTIL--YSRR--FFPYYVYNIIGGLDEEGKGAV 149 Query: 150 FETDPSGALIEYKATAIGSGRPVVMELLEKEY---------RDDITLDEGLELAITALTK 200 + DP G+ A GS ++ LL+ + ++LD + L Sbjct: 150 YSFDPVGSYQRDSFKAGGSASAMLQPLLDNQVGFKNMQNVEHVPLSLDRAMRLVKDVFIS 209 Query: 201 ANEDI--KPENVDVCIITVKD 219 A E + + +CI+T + Sbjct: 210 AAERDVYTGDALRICIVTKEG 230 >5LZP-A nrPDB Length = 242 Score = 117 bits (293), Expect = 6e-27, Method: Composition-based stats. Identities = 46/182 (25%), Positives = 69/182 (37%), Gaps = 8/182 (4%) Query: 37 TAIGIACKDGVVLAVDRRIT-SKLVKIRSIEKIFQIDDHVAAATSGLVADARVLIDRARL 95 T + + GVV+A DRR T ++ R + K++ DD+ A +G A A + Sbjct: 2 TIVALKYPGGVVMAGDRRSTQGNMISGRDVRKVYITDDYTATGIAGTAAVAVEFARLYAV 61 Query: 96 EAQIYRLTYGEEIS----IEMLAKKICDIKQAYTQHGGVRPFGVSLLIAGIDKNE-ARLF 150 E + Y G ++ I LA + A Q P I D R+ Sbjct: 62 ELEHYEKLEGVPLTFAGKINRLAIMVRGNLAAAMQGLLALPLLAGYDIHASDPQSAGRIV 121 Query: 151 ETDPSGALI--EYKATAIGSGRPVVMELLEKEYRDDITLDEGLELAITALTKANEDIKPE 208 D +G E A+GSG ++K Y D GL +A+ AL A +D Sbjct: 122 SFDAAGGWNIEEEGYQAVGSGSLFAKSSMKKLYSQVTDGDSGLRVAVEALYDAADDDSAT 181 Query: 209 NV 210 Sbjct: 182 GG 183 >5VFT-S nrPDB Length = 213 Score = 116 bits (292), Expect = 6e-27, Method: Composition-based stats. Identities = 41/201 (20%), Positives = 81/201 (40%), Gaps = 17/201 (8%) Query: 32 VRRGTTAIGIACKDGVVLAVDRRITSKL-VKIRSIEKIFQIDDHVAAATSGLVADARVLI 90 V G T + IA +D ++A D R++ + R K +++ D SG D L Sbjct: 6 VFNGGTILAIAGEDFAIVASDTRLSEGFSIHTRDSPKCYKLTDKTVIGCSGFHGDCLTLT 65 Query: 91 DRARLEAQIYRLTYGEEISIEMLAKKICDIKQAYTQHGGVRPFGVSLLIAGIDKNE-ARL 149 ++Y+ + + ++ +A + I Y++ P+ V +I G+D+ + Sbjct: 66 KIIEARLKMYKHSNNKAMTTGAIAAMLSTIL--YSRR--FFPYYVYNIIGGLDEEGKGAV 121 Query: 150 FETDPSGALIEYKATAIGSGRPVVMELLEKEY---------RDDITLDEGLELAITALTK 200 + DP G+ A GS ++ LL+ + ++LD + L Sbjct: 122 YSFDPVGSYQRDSFKAGGSASAMLQPLLDNQVGFKNMQNVEHVPLSLDRAMRLVKDVFIS 181 Query: 201 ANEDI--KPENVDVCIITVKD 219 A E + + +CI+T + Sbjct: 182 AAERDVYTGDALRICIVTKEG 202 >6EPF-6 nrPDB Length = 240 Score = 115 bits (288), Expect = 2e-26, Method: Composition-based stats. Identities = 52/238 (21%), Positives = 96/238 (40%), Gaps = 30/238 (12%) Query: 3 MVPPSAY---DRAITVFSPEGRLYQVE-----YAREAVRRGTTAIGIACKDGVVLAVDRR 54 M+ +AY DR + V P+G V+ YA G T + IA +D ++A D R Sbjct: 1 MLSTAAYRDPDREL-VMGPQGSAGPVQMRFSPYAF----NGGTVLAIAGEDFSIVASDTR 55 Query: 55 ITSKL-VKIRSIEKIFQIDDHVAAATSGLVADARVLIDRARLEAQIYRLTYGEEISIEML 113 ++ + R K +++ D SG D L ++Y+ + + ++ + Sbjct: 56 LSEGFSIHTRDSPKCYKLTDKTVIGCSGFHGDCLTLTKIIEARLKMYKHSNNKAMTTGAI 115 Query: 114 AKKICDIKQAYTQHGGVRPFGVSLLIAGIDKNE-ARLFETDPSGALIEYKATAIGSGRPV 172 A + I Y++ P+ V +I G+D+ ++ DP G+ A GS + Sbjct: 116 AAMLSTIL--YSRR--FFPYYVYNIIEGLDEEGKGAVYSFDPVGSYQRDSFKAGGSASAM 171 Query: 173 VMELLEKEY---------RDDITLDEGLELAITALTKANEDI--KPENVDVCIITVKD 219 + LL+ + +TLD + L A E + + +CI+T + Sbjct: 172 LQPLLDNQVGFKNMQNVEHVPLTLDRAMRLVKDVFISAAERDVYTGDALRICIVTKEG 229 >5FMG-J nrPDB Length = 218 Score = 106 bits (266), Expect = 7e-24, Method: Composition-based stats. Identities = 40/201 (19%), Positives = 74/201 (36%), Gaps = 22/201 (10%) Query: 34 RGTTAIGIACKDGVVLAVDRRITSKLVKIRS--IEKIFQIDDHVAAATSGLVADARVLID 91 G +G++ + V +A D R+ + S KIF+++++V SGL D + L + Sbjct: 8 NGGCVLGMSGSNCVAIACDLRLGANTFTTVSTKFSKIFKMNNNVYVGLSGLATDIQTLYE 67 Query: 92 RARLEAQIYRLTYGEEISIEMLAKKICDIKQAYTQHGGVRPFGVSLLIAGI------DKN 145 R +Y + E+ +E A + I + P+ V+ ++ G D+ Sbjct: 68 ILRYRVNLYEVRQDAEMDVECFANMLSSILYSNR----FSPYFVNPIVVGFKLKHYVDEE 123 Query: 146 E-------ARLFETDPSGALIEYKATAI-GSGRPVVMELLEKEYRDDITLDEGLELAITA 197 L D GA E + + G + + E Y D + E Sbjct: 124 GEKKVNYEPYLTAYDLIGAKCETRDFVVNGVTSEQLFGMCESLYVKDQDENGLFETISQC 183 Query: 198 LTKANEDI--KPENVDVCIIT 216 L A + +V ++T Sbjct: 184 LLSALDRDCISGWGAEVLVLT 204 >5FMG-N nrPDB Length = 265 Score = 102 bits (254), Expect = 2e-22, Method: Composition-based stats. Identities = 43/233 (18%), Positives = 85/233 (36%), Gaps = 44/233 (18%) Query: 32 VRRGTTAIGIACKDGVVLAVDRRIT-SKLVKIRSIEKIFQIDDHVAAATSGLVADARVLI 90 V GT+ I I K G+++A DR+ + K +++E+IF+I++ SG +ADA+ L Sbjct: 6 VVTGTSVIAIKYKHGIMIAADRKASYGSYAKFQNVERIFKINNKTVMGFSGELADAQYLH 65 Query: 91 DRA-RLEA-QIYRLTYGEEI-SIEMLAKKICDIKQAYTQHGGVRPFGVSLLIAGIDKNEA 147 + R + E++ + + + + Y + + P +++IAGI+ + Sbjct: 66 ELLTRKNINNLSEKKRKEDMYTPQHYHSYVSRVF--YVRKNRIDPLFNNIIIAGINSQKY 123 Query: 148 ------------------------------------RLFETDPSGALIEYKATAIGSGRP 171 + D G G R Sbjct: 124 DNNDDNVLLYTNKNNDDEQNEYKNNEEYKEIHKDDLYIGFVDMHGTNFCDDYITTGYARY 183 Query: 172 VVMELLEKEYRDDITLDEGLELAITALTKANEDIKPEN--VDVCIITVKDAQF 222 + LL Y+D++T +E L L + + + +T K ++ Sbjct: 184 FALTLLRDHYKDNMTEEEARILINECLRILYFRDATSSNFIQIVKVTSKGVEY 236 >6GOP-M nrPDB Length = 246 Score = 93.9 bits (232), Expect = 7e-20, Method: Composition-based stats. Identities = 35/231 (15%), Positives = 83/231 (35%), Gaps = 19/231 (8%) Query: 32 VRRGTTAIGIACKDGVVLAVDRRIT-SKLVKIRSIEKIFQIDDHVAAATSGLVADARVLI 90 + GT+ I + +GV++A D + L++ +E++ + D+ SG ++D + + Sbjct: 18 IVTGTSVISMKYDNGVIIAADNLGSYGSLLRFNGVERLIPVGDNTVVGISGDISDMQHIE 77 Query: 91 DRARLEAQIYRLTY-----GEEISIEMLAKKICDIKQAYTQHGGVRPFGVSLLIAGIDKN 145 + E + + + + + Y + + P ++++AG+ N Sbjct: 78 RLLKDLVTENAYDNPLADAEEALEPSYIFEYLATVM--YQRRSKMNPLWNAIIVAGVQSN 135 Query: 146 EAR-LFETDPSGALIEYKATAIGSGRPVVMELLEKEYRDDITL--------DEGLELAIT 196 + L + G A G G + LL K + + +E + A+ Sbjct: 136 GDQFLRYVNLLGVTYSSPTLATGFGAHMANPLLRKVVDRESDIPKTTVQVAEEAIVNAMR 195 Query: 197 ALTKANEDIKPENVDVCIITVKDAQFKKIPVEEIKKLIEKVKKKLNEENKK 247 L + N + II K+ +++ + K + + Sbjct: 196 VLYY-RDARSSRNFSLAII-DKNTGLTFKKNLQVENMKWDFAKDIKGYGTQ 244 >5FMG-H nrPDB Length = 252 Score = 90.8 bits (224), Expect = 5e-19, Method: Composition-based stats. Identities = 48/247 (19%), Positives = 94/247 (38%), Gaps = 54/247 (21%) Query: 36 TTAIGIACKDGVVLAVDRRITSK-LVKIRSIEKIFQIDDHVAAATSGLVADARVLIDRAR 94 TT IGI +GV+LA D R +S + + KI +I++++ SG A ++ +I+ + Sbjct: 1 TTIIGIIYDNGVMLACDSRTSSGTFISNKCSRKINRINENLYVCRSGASAHSQKIIEIIK 60 Query: 95 LEA-----------QIYR-------LTYGEEISIEMLAKK----------ICDIKQAYT- 125 + + TY EEI I+ + + K Y Sbjct: 61 HYCVSMKNENRKKGRFHEGETIYDETTYDEEIDIDSINYLDYNNNNDNNLVTKNKYFYED 120 Query: 126 QHGGVRPF-------------------GVSLLIAGIDK-NEARLFETDPSGALIEYKATA 165 + P +L+ G DK + +L+ + +G++IE A Sbjct: 121 KFNDYNPLVENVAHITKKIIYTNNNFLSCALIFGGYDKIKKQQLYAVNLNGSIIEKHDFA 180 Query: 166 I-GSGRPVVMELLEKEYRDDITLDEGLELAITALTKANEDIKPENVDVCIITVKDA---Q 221 + GSG + L+ +Y+ +T E L + + A + + I+ + + + Sbjct: 181 VSGSGSIYIQSYLQDKYKKFMTKKECFNLILNCVKYAMHNDNSSGGLIRIVNITKSFVEE 240 Query: 222 FKKIPVE 228 F + + Sbjct: 241 FTVVNTQ 247 >4HO7-A nrPDB Length = 179 Score = 60.3 bits (145), Expect = 8e-10, Method: Composition-based stats. Identities = 39/179 (21%), Positives = 72/179 (40%), Gaps = 20/179 (11%) Query: 36 TTAIGIACKDGVVLAVDRRIT--SKLVKIRSIEKIFQIDDHVAAATSGLVADARVLIDRA 93 TT + + D VVL DR++T ++V S K+ +I+D V +G ADA L+++ Sbjct: 1 TTILSVRKGDTVVLLGDRQVTLGERIVAKSSACKLRRINDDVVIGFAGSTADAISLMEKL 60 Query: 94 RLEAQIYRLTYGEEISIEMLAKKICDIKQAYTQHGGVRPFGVSLLIAGIDKNEARLFETD 153 + + L + ++ + + +R SL++ ++ E D Sbjct: 61 ENKIGEF---------PNQLTRAAVELAKEWRTDRALRRLEASLIVCSAEET----LEID 107 Query: 154 PSGALIEYKA---TAIGSGRPVVMELLEKEYRDDITLDEGLELAITALTKANEDIKPEN 209 G +I +A AIGSG D+ + ++A A+ A + N Sbjct: 108 GQGNVITPEADGIVAIGSGGTFAKAA--ARALIDVDGYDAEKIARKAMRIATDIDVFSN 164 >5LOY-A nrPDB Length = 240 Score = 59.2 bits (142), Expect = 2e-09, Method: Composition-based stats. Identities = 36/238 (15%), Positives = 85/238 (35%), Gaps = 19/238 (7%) Query: 36 TTAIGIACKDGVVLAVDRRITSKLVKIRSIEKIFQI----DDHVAAATSGLVADARVLID 91 T +GI +G+V A D R + + I + K+ + + T+G +A + +I Sbjct: 1 TYCVGIRLDEGLVFASDSRTNAGVDNISTFRKMHVFEVPGERVIVLLTAGNLATTQAVIS 60 Query: 92 RARLEAQIYRLTYGEEISIEMLAKKICDIKQAYTQH------GGVRPFGVSLLIAG-IDK 144 + S+ A+ + + + F S ++ G I Sbjct: 61 LLEERLKDPEERLLTAPSMFEAARLVGEALREVQARDAPALEADGVDFNASFILGGQIAG 120 Query: 145 NEARLFETDPSGALIEY----KATAIGSGRPVVMELLEKEYRDDITLDEGLELAITALTK 200 RLF P+G IE IG +L++ D +L++ + A+ + Sbjct: 121 EPPRLFLIYPAGNFIEATPDTPFFQIGE-TKYGKPILDRVITPDTSLEDAAKCALVSFDS 179 Query: 201 ANEDIKPENVDVCIITVKDAQFK---KIPVEEIKKLIEKVKKKLNEENKKEEENREET 255 + + ++ + + + ++E ++K+ +E ++ ++ + Sbjct: 180 TMRSNLSVGLPLDLLVYERDSLRVGHRRRIDEDDPYFRMLRKQWSEGLRQAFDSLPDP 237 >5LOX-A nrPDB Length = 242 Score = 54.6 bits (130), Expect = 5e-08, Method: Composition-based stats. Identities = 32/193 (16%), Positives = 68/193 (35%), Gaps = 19/193 (9%) Query: 36 TTAIGIACKDGVVLAVDRRITSKLVKIRSIEKIFQID----DHVAAATSGLVADARVLID 91 T + + DG+V A D R + + I + K+F + T+G +A ++ +I+ Sbjct: 1 TYCVAMHLADGLVFASDSRTNAGIDHIATFRKLFTFGTPGERLLVVQTAGNLATSQSVIN 60 Query: 92 RARLEAQIYRLTYGEEISIEMLAKKICDIKQAYTQH-----GGVRPFGVSLLIAG-IDKN 145 + + + S+ + + + G S ++ G I Sbjct: 61 LLQQRIRRDGASLLNVPSVYDATALVAETTREVMARDSGNLAGNTDLSCSFMVGGQIAGG 120 Query: 146 EARLFETDPSGALIEY----KATAIGSGRPVVMELLEKEYRDDITLDEGLELAITALTKA 201 L+ P G I+ +G +L++ ++T D LE A+ + Sbjct: 121 PPALYSIYPQGNFIQATPDTPFLQLGE-SKYGKPILDR----NLTFDTPLEQALRCALVS 175 Query: 202 NEDIKPENVDVCI 214 + N+ V + Sbjct: 176 FDSTIRSNLSVGM 188 >2FHG-A nrPDB Length = 250 Score = 54.2 bits (129), Expect = 6e-08, Method: Composition-based stats. Identities = 40/230 (17%), Positives = 90/230 (39%), Gaps = 34/230 (14%) Query: 26 EYAREAVRRGTTAIGIACKDGVVLAVDRRITSKLVKIRSIEKIFQIDDHVAAATSGLVAD 85 E AR+ + R + + +A GV+ + RS++KI ++ D V A +G + Sbjct: 20 ELARKGIARAKSVVALAYAGGVLFVAEN-------PSRSLQKISELYDRVGFAAAGKFNE 72 Query: 86 ARVLIDRARLEAQIYRLTYGEEISIEMLAKKICDIKQAYTQHGG------VRPFGVSLLI 139 L A Y ++ +++ ++ Y Q G +P+ V L + Sbjct: 73 FDNLRRGGIQFADTRGYAYDRR---DVTGRQLANV---YAQTLGTIFTEQAKPYEVELCV 126 Query: 140 AGIDKNE----ARLFETDPSGALIEYKATAI-GSGRPVVMELLEKEYRDDITLDEGLELA 194 A + L+ G++ + + G + L++ Y ++ +L + L +A Sbjct: 127 AEVAHYGETKRPELYRITYDGSIADEPHFVVMGGTTEPIANALKESYAENASLTDALRIA 186 Query: 195 ITALTKANEDIKPEN--------VDVCIITVKDAQ--FKKIPVEEIKKLI 234 + AL + D + ++V ++ + F++I ++ L+ Sbjct: 187 VAALRAGSADTSGGDQPTLGVASLEVAVLDANRPRRAFRRITGSALQALL 236 >5NYW-A nrPDB Length = 251 Score = 50.7 bits (120), Expect = 7e-07, Method: Composition-based stats. Identities = 34/196 (17%), Positives = 70/196 (35%), Gaps = 22/196 (11%) Query: 36 TTAIGIACKDGVVLAVDRRITSKLVKIRSIEKIFQI----DDHVAAATSGLVADARVLID 91 T + + G+ A D R + + I + K+ + + ++G +A + ++ Sbjct: 1 TYCVAMRLSSGLAFASDSRTNAGVDHISTFRKLHLFQQPGERTLVVQSAGNLATTQSIVS 60 Query: 92 RARLEAQIYRLTYGEEI-SIEMLAKKICDIKQA-------YTQHGGVRPFGVSLLIAGID 143 + T + S+ A + + + Q+ F +LL+ G Sbjct: 61 LLQRRCLDPEQTNLMNVASMYEAATLLGETVREVINRDSGAQQNSHGTDFNCNLLLGGQI 120 Query: 144 KNEA-RLFETDPSGALIEY----KATAIGSGRPVVMELLEKEYRDDITLDEGLELAITAL 198 K E RLF P G IE IG ++++ D LD+ ++ A+ Sbjct: 121 KGEGLRLFHIYPQGNFIEATQDTPYFQIGE-SKYGKPIIDRVLSYDTPLDQAMQCAL--- 176 Query: 199 TKANEDIKPENVDVCI 214 + + N+ V + Sbjct: 177 -ISMDSTLRSNLSVGL 191 >5JI2-A nrPDB Length = 184 Score = 50.3 bits (119), Expect = 7e-07, Method: Composition-based stats. Identities = 43/192 (22%), Positives = 70/192 (36%), Gaps = 41/192 (21%) Query: 36 TTAIGIACKDGVVLAVDRRIT-SKLVKIRSIEKIFQI-DDHVAAATSGLVADARVLIDRA 93 TT + + VV+A D + T V +++K+ ++ +D V A +G ADA L + Sbjct: 2 TTIVSVRRNGHVVIAGDGQATLGNTVMKGNVKKVRRLYNDKVIAGFAGGTADAFTLFELF 61 Query: 94 RLEAQIYRLTYGEEISIEMLAKKICDIKQAYTQHGGVRPFGV-----SLLIAGIDKNEAR 148 + ++++ ++ + D + V SL+I G Sbjct: 62 ERKLEMHQ-----GHLVKAAVELAKDWRTDRMLRKLEALLAVADETASLIITG----NGD 112 Query: 149 LFETDPSGALIEYKATAIGSGRPV----VMELLEKEYRDDITLDEGLELAITALTKANED 204 + + E AIGSG P LLE T E+A AL A Sbjct: 113 VVQ-------PENDLIAIGSGGPYAQAAARALLEN------TELSAREIAEKALDIA--- 156 Query: 205 IKPENVDVCIIT 216 D+CI T Sbjct: 157 -----GDICIYT 163 >5NYF-A nrPDB Length = 245 Score = 48.4 bits (114), Expect = 3e-06, Method: Composition-based stats. Identities = 39/216 (18%), Positives = 73/216 (33%), Gaps = 20/216 (9%) Query: 35 GTTAIGIACKDGVVLAVDRRITSKLVKIRSIEKIF---QIDDHVAAATS-GLVADARVLI 90 GT A+ + G+V A D R + + I +K+ Q + V S G +A + ++ Sbjct: 2 GTYAVAFRLERGLVFAADTRTNAGVDNIAQYKKLQLWRQPGERVFVLLSAGNLAATQAVV 61 Query: 91 ----DRARLEAQIYRLTYGEEISIEMLAKKICDIKQAYT------QHGGVRPFGVSLLIA 140 + E T ++ A+ + D + F + + Sbjct: 62 SLINEHLSQETDDEVTTLFTAPNMYRAARVVGDAVREARSIDGAALEASKLGFNTNFIFG 121 Query: 141 G-IDKNEARLFETDPSGALIEY----KATAIGSGRPVVMELLEKEYRDDITLDEGLELAI 195 G I RLF+ P G IE IG +L++ R D+ L E +L + Sbjct: 122 GQIKGERPRLFQIYPEGNFIEATDDTPFFQIGE-HKYGKPILDRVARSDMRLGEAAKLML 180 Query: 196 TALTKANEDIKPENVDVCIITVKDAQFKKIPVEEIK 231 + + + ++ + F + I Sbjct: 181 LSFDSTLRSNLSVGMPIDLVIYERDTFDVTREKRIS 216 >1OFH-G nrPDB Length = 174 Score = 43.8 bits (102), Expect = 7e-05, Method: Composition-based stats. Identities = 38/201 (18%), Positives = 78/201 (38%), Gaps = 36/201 (17%) Query: 36 TTAIGIACKDGVVLAVDRRIT-SKLVKIRSIEKIFQI-DDHVAAATSGLVADARVLIDRA 93 TT + + VV+ D +++ V + K+ ++ + V A +G ADA L + Sbjct: 1 TTIVSVRRNGQVVVGGDGQVSLGNTVMKGNARKVRRLYNGKVLAGFAGGTADAFTLFELF 60 Query: 94 RLEAQIYRLTYGEEISIEMLAKKICDIKQAYTQHGGVRPFGVSLLIAGIDKNEARLFETD 153 + ++++ L K ++ + + +R L++A D+ E+ + Sbjct: 61 ERKLEMHQ---------GHLLKSAVELAKDWRTDRALRKLEAMLIVA--DEKESLI--IT 107 Query: 154 PSGALI---EYKATAIGSGR----PVVMELLEKEYRDDITLDEGLELAITALTKANEDIK 206 G ++ E + AIGSG L+E T E+ +L A Sbjct: 108 GIGDVVQPEEDQILAIGSGGNYALSAARALVEN------TELSAHEIVEKSLRIA----- 156 Query: 207 PENVDVCIITVKDAQFKKIPV 227 D+C+ T + +++P Sbjct: 157 ---GDICVFTNTNFTIEELPN 174 >1M4Y-A nrPDB Length = 171 Score = 40.7 bits (94), Expect = 7e-04, Method: Composition-based stats. Identities = 43/189 (22%), Positives = 80/189 (42%), Gaps = 29/189 (15%) Query: 36 TTAIGIACKDGVVLAVDRRIT-SKLVKIRSIEKIFQIDD-HVAAATSGLVADARVLIDRA 93 TT + + V+ D ++T V + K+ ++ + V A +G VADA L DR Sbjct: 1 TTILVVRRNGQTVMGGDGQVTFGSTVLKGNARKVRKLGEGKVLAGFAGSVADAMTLFDRF 60 Query: 94 RLEAQIYRLTYGEEISIEMLAKKICDIKQAYTQHGGVRPFGVSLLIAGIDKNEARLFETD 153 + + + L K ++ + + +R LL+A ++ +F Sbjct: 61 EAKLREWGGN---------LTKAAVELAKDWRTDRVLRRLEALLLVA----DKENIFIIS 107 Query: 154 PSGALIE--YKATAIGSGRPVVMELLEKEYRD-DITLDEGLELAITALTKANEDIKPENV 210 +G +I+ A AIGSG P + + R+ D++ E +E A+T A Sbjct: 108 GNGEVIQPDDDAAAIGSGGPYALAAAKALLRNTDLSAREIVE---KAMTIA--------G 156 Query: 211 DVCIITVKD 219 ++CI T ++ Sbjct: 157 EICIYTNQN 165 >2Z3B-A nrPDB Length = 180 Score = 37.6 bits (86), Expect = 0.006, Method: Composition-based stats. Identities = 36/190 (18%), Positives = 69/190 (36%), Gaps = 30/190 (15%) Query: 34 RGTTAIGIACKDGVVLAVDRRIT--SKLVKIRSIEKIFQI-DDHVAAATSGLVADARVLI 90 TT + K ++ D ++T +V + K+ ++ + V A +G VADA L Sbjct: 4 HATTIFAVQHKGRSAMSGDGQVTFGQAVVMKHTARKVRKLFNGKVLAGFAGSVADAFTLF 63 Query: 91 DRARLEAQIYRLTYGEEISIEMLAKKICDIKQAYTQHGGVRPFGVSLLIAGID-----KN 145 ++ + + Y +++ A ++ + +R L++ D Sbjct: 64 EKFEAKLEEY------NGNLKRAAVELAK---EWRSDKVLRKLEAMLIVMNQDTLLLVSG 114 Query: 146 EARLFETDPSGALIEYKATAIGSGRPVVME---LLEKEYRDDITLDEGLELAITALTKAN 202 + E D AIGSG + L+K + ++ E+A AL A Sbjct: 115 TGEVIEPDDG-------ILAIGSGGNYALAAGRALKKHAGESMS---ASEIARAALETAG 164 Query: 203 EDIKPENVDV 212 E N + Sbjct: 165 EICVYTNDQI 174 >3TY6-A nrPDB Length = 183 Score = 36.5 bits (83), Expect = 0.011, Method: Composition-based stats. Identities = 35/187 (18%), Positives = 69/187 (36%), Gaps = 20/187 (10%) Query: 34 RGTTAIGIACKDGVVLAVDRRIT--SKLVKIRSIEKIFQI-DDHVAAATSGLVADARVLI 90 TT + +A D ++T + +V + K+ ++ V A +G VADA L Sbjct: 8 HATTIFAVHHNGECAMAGDGQVTMGNAVVMKHTARKVRKLFQGKVLAGFAGSVADAFTLF 67 Query: 91 DRARLEAQIYRLTYGEEISIEMLAKKICDIKQAYTQHGGVRPFGVSLLIAGIDKNEARLF 150 + + + Y ++EM + D +R L++ +DK L Sbjct: 68 EMFEGKLEEYNGNLQRA-AVEMAKQWRGDKM--------LRQLEAMLIV--MDKTTMLLV 116 Query: 151 ETDPSGALIEYKATAIGSGRPVVME---LLEKEYRDDITLDEGLELAITALTKANEDIKP 207 + AIGSG + L++ + +T ++A +L A + Sbjct: 117 SGTGEVIEPDDGILAIGSGGNYALSAGRALKQYASEHLT---AKQIAKASLEIAGDICVY 173 Query: 208 ENVDVCI 214 N ++ + Sbjct: 174 TNHNIIV 180 >6DTT-A nrPDB Length = 383 Score = 32.6 bits (73), Expect = 0.16, Method: Composition-based stats. Identities = 26/81 (32%), Positives = 31/81 (38%), Gaps = 13/81 (16%) Query: 9 YDRAITVFSPEGRLYQVEYAREAVRRGTTAIGIACKDGVVLAVDRRITSKLVKIRSIEKI 68 YD A+ FS G+LY V YA EAV I KD V + IEK Sbjct: 88 YDTALKAFSYGGKLYGVPYAMEAVAL------IYNKDYV-------DSVPKTMDELIEKA 134 Query: 69 FQIDDHVAAATSGLVADARVL 89 QID+ G + D Sbjct: 135 KQIDEEYGGEVRGFIYDVANF 155 >2E21-A nrPDB Length = 317 Score = 31.4 bits (70), Expect = 0.38, Method: Composition-based stats. Identities = 16/53 (30%), Positives = 26/53 (49%), Gaps = 1/53 (1%) Query: 52 DRRITSKLVKIRSIEKIFQIDDHVAAATSGLVADARVLIDRARLEAQIYRLTY 104 + R+ K++ +++ EKIF + V A SG V D+ VL D + L Sbjct: 4 ESRVIRKVLALQNDEKIFSGERRVLIAFSGGV-DSVVLTDVLLKLKNYFSLKE 55 >3H8L-A nrPDB Length = 409 Score = 30.7 bits (68), Expect = 0.60, Method: Composition-based stats. Identities = 17/74 (22%), Positives = 33/74 (44%), Gaps = 4/74 (5%) Query: 142 IDKNEARLFETDPSGALI--EYKATAIGSGRPVVMELLEKEYRDDITLDEGLELAITALT 199 ID + ++ T P G++ EY +G G + EL++ + ++ E E A L Sbjct: 81 IDAKSSMVYYTKPDGSMAEEEYDYVIVGIGAHLATELVKGWDKYGYSVCEP-EFATK-LR 138 Query: 200 KANEDIKPENVDVC 213 + E + N+ + Sbjct: 139 EKLESFQGGNIAIG 152 >5B46-A nrPDB Length = 628 Score = 30.3 bits (67), Expect = 0.94, Method: Composition-based stats. Identities = 15/62 (24%), Positives = 27/62 (43%), Gaps = 2/62 (3%) Query: 197 ALTKANEDIKPENVDVCIITVKDAQFKKIPVEEIKKLIEKVKKKLNEENKKEEENREETK 256 A+ A E++ + + ++ VK F P +KK++ K + EN + E Sbjct: 526 AILDAMEELSKDGIKTMMVQVK--MFNPYPKNLMKKILSGKSKIIAVENNYNAQGAEVLA 583 Query: 257 EK 258 EK Sbjct: 584 EK 585 >2V3B-A nrPDB Length = 384 Score = 29.9 bits (66), Expect = 1.2, Method: Composition-based stats. Identities = 24/130 (18%), Positives = 43/130 (33%), Gaps = 21/130 (16%) Query: 28 AREAVRRGTTAIGIACKDGVVLAVDRRITSKLVKIRSIEKIFQID---------DHVAAA 78 A +AV+ G +G+ G VLA ++ L S ++ D A Sbjct: 189 AAKAVQAGLEGLGVRFHLGPVLASLKKAGEGLEAHLSDGEVIPCDLVVSAVGLRPRTELA 248 Query: 79 T-SGLVADARVLIDRA--RLEAQIYR---------LTYGEEISIEMLAKKICDIKQAYTQ 126 +GL + +++DR+ A IY L + + A+ + Sbjct: 249 FAAGLAVNRGIVVDRSLRTSHANIYALGDCAEVDGLNLLYVMPLMACARALAQTLAGNPS 308 Query: 127 HGGVRPFGVS 136 P V+ Sbjct: 309 QVAYGPMPVT 318 >2GHB-A nrPDB Length = 382 Score = 29.5 bits (65), Expect = 1.4, Method: Composition-based stats. Identities = 11/25 (44%), Positives = 16/25 (64%) Query: 9 YDRAITVFSPEGRLYQVEYAREAVR 33 Y+ A+ FS G+LY + YA EA+ Sbjct: 88 YETALNAFSYGGKLYGIPYAMEAIA 112 >1VRD-A nrPDB Length = 494 Score = 29.5 bits (65), Expect = 1.5, Method: Composition-based stats. Identities = 17/80 (21%), Positives = 35/80 (43%), Gaps = 7/80 (8%) Query: 182 RDDITLDEGLELAITALTKANEDIKPENVDVCIITVKDAQFKKIPVEEIKKLIEKVKKKL 241 D+T+ E ++L + E V ++T +D +F+K ++IK L+ +K + Sbjct: 109 TPDMTVKEAIDLMAEYKIGGLPVVDEEGRLVGLLTNRDVRFEKNLSKKIKDLMTPREKLI 168 Query: 242 NEENKKEEENREETKEKQEE 261 + + EK +E Sbjct: 169 VA-------PPDISLEKAKE 181 >3WNB-A nrPDB Length = 370 Score = 29.1 bits (64), Expect = 1.8, Method: Composition-based stats. Identities = 11/35 (31%), Positives = 17/35 (48%), Gaps = 3/35 (8%) Query: 41 IACKDGVVLAVDRRITSKLVKIRSIEKIFQIDDHV 75 + K VVL V ++ SK + KIF +D + Sbjct: 203 VTGKGCVVLGVVKQGISK---DKDKTKIFPLDRDI 234 >1JSO-A nrPDB Length = 325 Score = 29.1 bits (64), Expect = 1.9, Method: Composition-based stats. Identities = 13/61 (21%), Positives = 23/61 (37%), Gaps = 8/61 (13%) Query: 16 FSPEGRLYQVEYAREAVRRGTTAI---GIACKDGVVLAVDRRITSKLVKIRSIEKIFQID 72 F G EYA + V++G +AI G+ + + + + + I S I Sbjct: 241 FESNGNFIAPEYAYKIVKKGGSAIMKSGLEYGNC-----NTKCQTPMGAINSSMPFHNIH 295 Query: 73 D 73 Sbjct: 296 P 296 >3T51-B nrPDB Length = 336 Score = 29.1 bits (64), Expect = 2.2, Method: Composition-based stats. Identities = 10/29 (34%), Positives = 14/29 (48%) Query: 45 DGVVLAVDRRITSKLVKIRSIEKIFQIDD 73 DGV+ A D R + K + KI +D Sbjct: 138 DGVITAFDLRAGMNIAKDNVVAKIQGMDP 166 >3OPO-A nrPDB Length = 413 Score = 28.8 bits (63), Expect = 2.3, Method: Composition-based stats. Identities = 10/29 (34%), Positives = 14/29 (48%) Query: 45 DGVVLAVDRRITSKLVKIRSIEKIFQIDD 73 DGV+ A D R + K + KI +D Sbjct: 215 DGVITAFDLRAGMNIAKDNVVAKIQGMDP 243 >2WRH-H nrPDB Length = 324 Score = 28.8 bits (63), Expect = 2.3, Method: Composition-based stats. Identities = 15/64 (23%), Positives = 23/64 (35%), Gaps = 5/64 (7%) Query: 12 AITVFSPEGRLYQVEYAREAVRRGTTAIGIACKDGVVLAVDRRITSKLVKIRS---IEKI 68 F G L YA A+ +G+ + GI D V D R + + S + + Sbjct: 236 DTITFEATGNLIAPWYAF-ALNKGSDS-GIITSDAPVHNCDTRCQTPHGALNSSLPFQNV 293 Query: 69 FQID 72 I Sbjct: 294 HPIT 297 >1G61-A nrPDB Length = 228 Score = 28.8 bits (63), Expect = 2.9, Method: Composition-based stats. Identities = 14/43 (32%), Positives = 21/43 (48%), Gaps = 4/43 (9%) Query: 22 LYQVEYAREAVRR-GTTAIG---IACKDGVVLAVDRRITSKLV 60 L++VEY + GTT++G IA G V+ D L+ Sbjct: 178 LFKVEYIGKGTANKGTTSVGACIIANSKGAVVGGDTTGPELLI 220 >1RFZ-A nrPDB Length = 168 Score = 28.4 bits (62), Expect = 3.2, Method: Composition-based stats. Identities = 7/25 (28%), Positives = 15/25 (60%) Query: 176 LLEKEYRDDITLDEGLELAITALTK 200 L+ +Y D+T++E +E ++K Sbjct: 36 YLQSKYHPDLTMEECIENVNRVISK 60 >5UDI-A nrPDB Length = 479 Score = 27.6 bits (60), Expect = 5.0, Method: Composition-based stats. Identities = 14/49 (28%), Positives = 21/49 (42%) Query: 153 DPSGALIEYKATAIGSGRPVVMELLEKEYRDDITLDEGLELAITALTKA 201 + G +A A S + V K YR ++D+ LEL AL + Sbjct: 234 EAEGEKYIEEALANMSSQTYVFRYAAKFYRRKGSVDKALELLKKALQET 282 >5A5T-C nrPDB Length = 843 Score = 27.6 bits (60), Expect = 5.3, Method: Composition-based stats. Identities = 8/34 (23%), Positives = 17/34 (50%) Query: 228 EEIKKLIEKVKKKLNEENKKEEENREETKEKQEE 261 ++I+K + + + E++ +E EK EE Sbjct: 73 QKIRKYNRDFESHITNYKQNPEQSADEDAEKNEE 106 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.311 0.146 0.372 Lambda K H 0.267 0.0448 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 9,216,039 Number of Sequences: 36641 Number of extensions: 361384 Number of successful extensions: 2390 Number of sequences better than 10.0: 107 Number of HSP's better than 10.0 without gapping: 168 Number of HSP's successfully gapped in prelim test: 67 Number of HSP's that attempted gapping in prelim test: 1829 Number of HSP's gapped (non-prelim): 301 length of query: 261 length of database: 10,336,785 effective HSP length: 95 effective length of query: 166 effective length of database: 6,855,890 effective search space: 1138077740 effective search space used: 1138077740 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 58 (26.8 bits)