BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q5FW60 (181 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 2L9C-A nrPDB 331 1e-91 3KFG-A nrPDB 275 8e-75 5X7Y-A nrPDB 176 6e-45 1GM6-A nrPDB 169 5e-43 1EW3-A nrPDB 166 4e-42 2R73-A nrPDB 94 4e-20 3L4R-A nrPDB 76 1e-14 1E5P-A nrPDB 71 3e-13 1JZU-A nrPDB 66 9e-12 3SAO-A nrPDB 64 3e-11 3O22-A nrPDB 63 7e-11 1E06-A nrPDB 59 1e-09 3U9P-C nrPDB 57 4e-09 4WFU-A nrPDB 57 6e-09 2E4J-A nrPDB 56 7e-09 2K23-A nrPDB 53 6e-08 1G85-A nrPDB 53 7e-08 4QAE-A nrPDB 53 8e-08 1EXS-A nrPDB 50 5e-07 4R0B-A nrPDB 50 6e-07 5N47-A nrPDB 47 5e-06 5MHH-A nrPDB 46 8e-06 1EPB-A nrPDB 46 9e-06 5N48-A nrPDB 45 2e-05 3DTQ-A nrPDB 45 2e-05 4MVK-A nrPDB 44 4e-05 4IAX-A nrPDB 43 7e-05 5NKN-A nrPDB 43 7e-05 5JR8-A nrPDB 43 7e-05 6GQZ-A nrPDB 43 1e-04 3EYC-A nrPDB 42 1e-04 4GH7-A nrPDB 42 2e-04 4RUN-A nrPDB 41 3e-04 4MVL-A nrPDB 41 4e-04 1BBP-A nrPDB 31 0.35 1GKA-B nrPDB 30 0.39 3CQR-A nrPDB 28 2.5 1JYJ-A nrPDB 28 2.6 4PSQ-B nrPDB 28 2.6 4AC8-A nrPDB 28 2.9 1DMG-A nrPDB 27 4.4 1G0D-A nrPDB 27 4.7 1RKQ-A nrPDB 26 8.2 >2L9C-A nrPDB Length = 176 Score = 331 bits (848), Expect = 1e-91, Method: Compositional matrix adjust. Identities = 162/162 (100%), Positives = 162/162 (100%) Query: 20 EEASSMERNFNVEKINGEWYTIMLATDKREKIEEHGSMRVFVEYIHVLENSLALKFHIII 79 EEASSMERNFNVEKINGEWYTIMLATDKREKIEEHGSMRVFVEYIHVLENSLALKFHIII Sbjct: 15 EEASSMERNFNVEKINGEWYTIMLATDKREKIEEHGSMRVFVEYIHVLENSLALKFHIII 74 Query: 80 NEECSEIFLVADKTEKAGEYSVTYDGSNTFTILKTDYDNYIMIHLINKKDGETFQLMELY 139 NEECSEIFLVADKTEKAGEYSVTYDGSNTFTILKTDYDNYIMIHLINKKDGETFQLMELY Sbjct: 75 NEECSEIFLVADKTEKAGEYSVTYDGSNTFTILKTDYDNYIMIHLINKKDGETFQLMELY 134 Query: 140 GREPDLSSDIKEKFAQLSEEHGIVRENIIDLTNANRCLEARE 181 GREPDLSSDIKEKFAQLSEEHGIVRENIIDLTNANRCLEARE Sbjct: 135 GREPDLSSDIKEKFAQLSEEHGIVRENIIDLTNANRCLEARE 176 >3KFG-A nrPDB Length = 162 Score = 275 bits (703), Expect = 8e-75, Method: Compositional matrix adjust. Identities = 131/162 (80%), Positives = 148/162 (91%) Query: 20 EEASSMERNFNVEKINGEWYTIMLATDKREKIEEHGSMRVFVEYIHVLENSLALKFHIII 79 EEA+S +N NVEKINGEW++I+LA+DKREKIEEHGSMRVFVE+IHVLENSLA KFH +I Sbjct: 1 EEATSKGQNLNVEKINGEWFSILLASDKREKIEEHGSMRVFVEHIHVLENSLAFKFHTVI 60 Query: 80 NEECSEIFLVADKTEKAGEYSVTYDGSNTFTILKTDYDNYIMIHLINKKDGETFQLMELY 139 + ECSEIFLVADKTEKAGEYSV YDG NTFTILKTDYDNYIM HLIN+KDG+TFQLMELY Sbjct: 61 DGECSEIFLVADKTEKAGEYSVMYDGFNTFTILKTDYDNYIMFHLINEKDGKTFQLMELY 120 Query: 140 GREPDLSSDIKEKFAQLSEEHGIVRENIIDLTNANRCLEARE 181 GR+ DL+SDIKEKF +L EEHGI++ENIIDLT NRCL+ARE Sbjct: 121 GRKADLNSDIKEKFVKLCEEHGIIKENIIDLTKTNRCLKARE 162 >5X7Y-A nrPDB Length = 177 Score = 176 bits (445), Expect = 6e-45, Method: Compositional matrix adjust. Identities = 85/165 (51%), Positives = 120/165 (72%), Gaps = 1/165 (0%) Query: 18 HAEEASSMERNFNVEKINGEWYTIMLATDKREKIEEHGSMRVFVEYIHVLENS-LALKFH 76 H EE ++ NF++ KI+G+WY+I+LA+D +EKIEE+GSMRVFV+ I VL NS L H Sbjct: 3 HEEENDVVKGNFDISKISGDWYSILLASDIKEKIEENGSMRVFVKDIEVLSNSSLIFTMH 62 Query: 77 IIINEECSEIFLVADKTEKAGEYSVTYDGSNTFTILKTDYDNYIMIHLINKKDGETFQLM 136 +N +C++I L+ +KTEK GEY V +DG N F I++T Y++YI+ HL N + FQLM Sbjct: 63 TKVNGKCTKISLICNKTEKDGEYDVVHDGYNLFRIIETAYEDYIIFHLNNVNQEQEFQLM 122 Query: 137 ELYGREPDLSSDIKEKFAQLSEEHGIVRENIIDLTNANRCLEARE 181 ELYGR+PD+S +KEKF + + I +ENI+DLT +RCL+AR+ Sbjct: 123 ELYGRKPDVSPKVKEKFVRYCQGMEIPKENILDLTQVDRCLQARQ 167 >1GM6-A nrPDB Length = 175 Score = 169 bits (429), Expect = 5e-43, Method: Compositional matrix adjust. Identities = 77/154 (50%), Positives = 113/154 (73%), Gaps = 2/154 (1%) Query: 28 NFNVEKINGEWYTIMLATDKREKIEEHGSMRVFVEYIHVLENS-LALKFHIIINEECSEI 86 NF+ KI GEWY+I+LA+D +E IEE+GSMRVFVE+I VL+NS LA KF +N EC++ Sbjct: 12 NFDASKIAGEWYSILLASDAKENIEENGSMRVFVEHIRVLDNSSLAFKFQRKVNGECTDF 71 Query: 87 FLVADKTEKAGEYSVTYDGSNTFTILKTDYDNYIMIHLINKKDGETFQLMELYGREPDLS 146 + V DK G Y+V Y G N F +L+ +Y +Y+++HL++ +TFQLME YGR+PD+ Sbjct: 72 YAVCDKVGD-GVYTVAYYGENKFRLLEVNYSDYVILHLVDVNGDKTFQLMEFYGRKPDVE 130 Query: 147 SDIKEKFAQLSEEHGIVRENIIDLTNANRCLEAR 180 +K+KF ++ +++GI++ENIIDLT +RC + R Sbjct: 131 PKLKDKFVEICQQYGIIKENIIDLTKIDRCFQLR 164 >1EW3-A nrPDB Length = 159 Score = 166 bits (421), Expect = 4e-42, Method: Compositional matrix adjust. Identities = 79/155 (50%), Positives = 112/155 (72%), Gaps = 1/155 (0%) Query: 27 RNFNVEKINGEWYTIMLATDKREKIEEHGSMRVFVEYIHVLENS-LALKFHIIINEECSE 85 RNF++ KI+GEWY+I LA+D +EKIEE+GSMRVFV+ I L+NS L ++ +N EC+E Sbjct: 4 RNFDISKISGEWYSIFLASDVKEKIEENGSMRVFVDVIRALDNSSLYAEYQTKVNGECTE 63 Query: 86 IFLVADKTEKAGEYSVTYDGSNTFTILKTDYDNYIMIHLINKKDGETFQLMELYGREPDL 145 +V DKTE+ G YS+ YDG N F I + + D +I+++L+N FQL E Y REPD+ Sbjct: 64 FPMVFDKTEEDGVYSLNYDGYNVFRISEFENDEHIILYLVNFDKDRPFQLFEFYAREPDV 123 Query: 146 SSDIKEKFAQLSEEHGIVRENIIDLTNANRCLEAR 180 S +IKE+F ++ ++ GIV+ENIIDLT +RC + R Sbjct: 124 SPEIKEEFVKIVQKRGIVKENIIDLTKIDRCFQLR 158 >2R73-A nrPDB Length = 166 Score = 93.6 bits (231), Expect = 4e-20, Method: Compositional matrix adjust. Identities = 53/165 (32%), Positives = 88/165 (53%) Query: 12 LTLVCVHAEEASSMERNFNVEKINGEWYTIMLATDKREKIEEHGSMRVFVEYIHVLENSL 71 L C +EE S E+ E+++ W+T++LA+ R IEE G R F++ I V +L Sbjct: 2 LQPECSRSEEDLSDEKERKWEQLSRHWHTVVLASSDRSLIEEEGPFRNFIQNITVESGNL 61 Query: 72 ALKFHIIINEECSEIFLVADKTEKAGEYSVTYDGSNTFTILKTDYDNYIMIHLINKKDGE 131 F N +C ++L A KTE+A ++ + Y G+N + + Y N DG+ Sbjct: 62 NGFFLTRKNGQCIPLYLTAFKTEEARQFKLNYYGTNDVYYESSKPNEYAKFIFYNYHDGK 121 Query: 132 TFQLMELYGREPDLSSDIKEKFAQLSEEHGIVRENIIDLTNANRC 176 + L+GR P+LS++IK++F + G RENI+D++ + C Sbjct: 122 VNVVANLFGRTPNLSNEIKKRFEEDFMNRGFRRENILDISEVDHC 166 >3L4R-A nrPDB Length = 170 Score = 75.9 bits (185), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 39/161 (24%), Positives = 87/161 (54%) Query: 21 EASSMERNFNVEKINGEWYTIMLATDKREKIEEHGSMRVFVEYIHVLENSLALKFHIIIN 80 E + E +E+++G W+++ LA++K + I+ G RVF+ + + +L I + Sbjct: 2 EGNHEEPQGGLEELSGRWHSVALASNKSDLIKPWGHFRVFIHSMSAKDGNLHGDILIPQD 61 Query: 81 EECSEIFLVADKTEKAGEYSVTYDGSNTFTILKTDYDNYIMIHLINKKDGETFQLMELYG 140 +C ++ L A KT + ++ + Y G N + + D +Y+++++IN+ + +T + L Sbjct: 62 GQCEKVSLTAFKTATSNKFDLEYWGHNDLYLAEVDPKSYLILYMINQYNDDTSLVAHLMV 121 Query: 141 REPDLSSDIKEKFAQLSEEHGIVRENIIDLTNANRCLEARE 181 R+ D F + E+ G+ ++ I+ L++ +RC +R+ Sbjct: 122 RDLSRQQDFLPAFESVCEDIGLHKDQIVVLSDDDRCQGSRD 162 >1E5P-A nrPDB Length = 151 Score = 70.9 bits (172), Expect = 3e-13, Method: Compositional matrix adjust. Identities = 40/148 (27%), Positives = 75/148 (50%), Gaps = 3/148 (2%) Query: 33 KINGEWYTIMLATDKREKIEEHGSMRVFVEYIHVLENS--LALKFHIIINEECSEIFLVA 90 ++ G+WYTI++A D EKIEE G +R + +I +N + + F++I N +CS+ ++ Sbjct: 5 ELQGKWYTIVIAADNLEKIEEGGPLRFYFRHIDCYKNCSEMEITFYVITNNQCSKTTVIG 64 Query: 91 DKTEKAGEYSVTYDGSNTFTILKTDYDNYIMIHLINKKDGETFQLMELYGREPDLSSDIK 150 + G Y ++G+N F L D + + G+ ++ + G+ L+ + Sbjct: 65 -YLKGNGTYETQFEGNNIFQPLYITSDKIFFTNKNMDRAGQETNMIVVAGKGNALTPEEN 123 Query: 151 EKFAQLSEEHGIVRENIIDLTNANRCLE 178 E Q + E I ENI+++ + C E Sbjct: 124 EILVQFAHEKKIPVENILNILATDTCPE 151 >1JZU-A nrPDB Length = 157 Score = 65.9 bits (159), Expect = 9e-12, Method: Compositional matrix adjust. Identities = 39/144 (27%), Positives = 64/144 (44%), Gaps = 1/144 (0%) Query: 34 INGEWYTIMLATDKREKIEEHGSMRVFVEYIHVL-ENSLALKFHIIINEECSEIFLVADK 92 I G+WY + LA++ + E M++ + I L E+ L + + + C + K Sbjct: 9 IAGKWYVVALASNTEFFLREKDKMKMAMARISFLGEDELKVSYAVPKPNGCRKWETTFKK 68 Query: 93 TEKAGEYSVTYDGSNTFTILKTDYDNYIMIHLINKKDGETFQLMELYGREPDLSSDIKEK 152 T GE + + +L TDY +Y +I+ KDG T +M LY R P++S Sbjct: 69 TSDDGEVYYSEEAKKKVEVLDTDYKSYAVIYATRVKDGRTLHMMRLYSRSPEVSPAATAI 128 Query: 153 FAQLSEEHGIVRENIIDLTNANRC 176 F +L+ E E + L C Sbjct: 129 FRKLAGERNYTDEMVAMLPRQEEC 152 >3SAO-A nrPDB Length = 160 Score = 63.9 bits (154), Expect = 3e-11, Method: Compositional matrix adjust. Identities = 39/144 (27%), Positives = 65/144 (45%), Gaps = 1/144 (0%) Query: 34 INGEWYTIMLATDKREKIEEHGSMRVFVEYIHVL-ENSLALKFHIIINEECSEIFLVADK 92 + G+WY + LA++ + E G M++ + I L E+ L + + + C + K Sbjct: 8 VAGKWYIVALASNTDFFLAEKGKMKMVMARISFLGEDELEVSYAAPSPKGCRKWETTFKK 67 Query: 93 TEKAGEYSVTYDGSNTFTILKTDYDNYIMIHLINKKDGETFQLMELYGREPDLSSDIKEK 152 T GE + + T +L TDY +Y +I KDG T +M LY R ++S Sbjct: 68 TSDDGEVYYSEEAEKTVEVLDTDYKSYAVIFATRVKDGRTLHMMRLYSRSREVSPTAMAI 127 Query: 153 FAQLSEEHGIVRENIIDLTNANRC 176 F +L+ E E + L + C Sbjct: 128 FRKLARERNYTDEMVAVLPSQAAC 151 >3O22-A nrPDB Length = 162 Score = 63.2 bits (152), Expect = 7e-11, Method: Compositional matrix adjust. Identities = 35/159 (22%), Positives = 73/159 (45%), Gaps = 5/159 (3%) Query: 24 SMERNFNVEKINGEWYTIMLATDKREKIEEHGSMRVFVEYI-HVLENSLALKFHIIINEE 82 S++ NF +K G W++ LA++ E+ ++ + + + L L + + Sbjct: 1 SVQPNFQQDKFLGRWFSAGLASNSSWLREKKAALSMAKSVVAPATDGGLNLTSTFLRKNQ 60 Query: 83 CSEIFLVADKTEKAGEYSVT---YDGSNTFTILKTDYDNYIMIHLINKK-DGETFQLMEL 138 C ++ G YS + + + ++++TDYD Y +++ K GE F++ L Sbjct: 61 CETRTMLLQPAGSLGSYSYRSPHWGSTYSVSVVETDYDQYALLYSQGSKGPGEDFRMATL 120 Query: 139 YGREPDLSSDIKEKFAQLSEEHGIVRENIIDLTNANRCL 177 Y R +++KEKF + G + I+ L ++C+ Sbjct: 121 YSRTQTPRAELKEKFTAFCKAQGFTEDTIVFLPQTDKCM 159 >1E06-A nrPDB Length = 157 Score = 58.5 bits (140), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 40/146 (27%), Positives = 71/146 (48%), Gaps = 3/146 (2%) Query: 33 KINGEWYTIMLATDKREKIEEHGSMRVFVEYIHV--LENSLALKFHIIINEECSEIFLVA 90 +++G+W T + + EKI E+ +VF+ I E+ + L F N C E L+ Sbjct: 11 ELSGKWITSYIGSSDLEKIGENAPFQVFMRSIEFDDKESKVYLNFFSKENGICEEFSLIG 70 Query: 91 DKTEKAGEYSVTYDGSNTFTILKTDYDNYIMIHLINKKDGETFQLMELYGREPDLSSDIK 150 K E Y V Y G+N F + I+ ++ ++G+ + L G+ D+ Sbjct: 71 TKQE-GNTYDVNYAGNNKFVVSYASETALIISNINVDEEGDKTIMTGLLGKGTDIEDQDL 129 Query: 151 EKFAQLSEEHGIVRENIIDLTNANRC 176 EKF +++ E+GI ENI+++ + C Sbjct: 130 EKFKEVTRENGIPEENIVNIIERDDC 155 >3U9P-C nrPDB Length = 182 Score = 57.0 bits (136), Expect = 4e-09, Method: Compositional matrix adjust. Identities = 35/164 (21%), Positives = 80/164 (48%), Gaps = 10/164 (6%) Query: 24 SMERNFNVEKINGEWYTIMLATDKREKIEEHGSMRVFVEYIHVLENSLALKFHIIINEE- 82 ++ +F ++ G WY + LA + +K E GS ++ + EN+ I++ ++ Sbjct: 19 PLQPDFRSDQFRGRWYVVGLAGNAVQKKTE-GSFTMYSTIYELQENNSYNVTSILVRDQD 77 Query: 83 --CSEIFLVADKTEKAGEYSV----TYDGSNTFTI--LKTDYDNYIMIHLINKKDGETFQ 134 C + +AG++++ Y ++ + TDY+ + M+ + + + Sbjct: 78 QGCRYWIRTFVPSSRAGQFTLGNMHRYPQVQSYNVQVATTDYNQFAMVFFRKTSENKQYF 137 Query: 135 LMELYGREPDLSSDIKEKFAQLSEEHGIVRENIIDLTNANRCLE 178 + LYGR +LS ++KE+F + ++ G+ +NII ++C++ Sbjct: 138 KITLYGRTKELSPELKERFTRFAKSLGLKDDNIIFSVPTDQCID 181 >4WFU-A nrPDB Length = 156 Score = 56.6 bits (135), Expect = 6e-09, Method: Compositional matrix adjust. Identities = 40/147 (27%), Positives = 73/147 (49%), Gaps = 6/147 (4%) Query: 33 KINGEWYTIMLATDKREKIEEHGSMRVFVEYIHVLEN--SLALKFHIIINEECSEIFLVA 90 KI GEW I A D ++KI E G +R + I + + SL++ F++ C + VA Sbjct: 11 KIPGEWRIIYAAADNKDKIVEGGPLRNYYRRIECINDCESLSITFYLKDQGTCLLLTEVA 70 Query: 91 DKTEKAGEYSVTYDGSNTFTILKTDYDNYIMIHLINKKDGETF-QLMELYGREPDLSSDI 149 K ++ Y + + G+NT ++ + +++ + DGE ++ E + + + Sbjct: 71 -KRQEGYVYVLEFYGTNTLEVIHVSEN--MLVTYVENYDGERITKMTEGLAKGTSFTPEE 127 Query: 150 KEKFAQLSEEHGIVRENIIDLTNANRC 176 EK+ QL+ E G+ ENI +L + C Sbjct: 128 LEKYQQLNSERGVPNENIENLIKTDNC 154 >2E4J-A nrPDB Length = 167 Score = 56.2 bits (134), Expect = 7e-09, Method: Compositional matrix adjust. Identities = 37/160 (23%), Positives = 74/160 (46%), Gaps = 5/160 (3%) Query: 24 SMERNFNVEKINGEWYTIMLATDKREKIEEHGSMRVFVEYIHV-LENSLALKFHIIINEE 82 +++ NF +K G WY+ LA++ E+ + + + E L L + + Sbjct: 7 TVQPNFQQDKFLGRWYSAGLASNSSWFREKKAVLYMCKTVVAPSTEGGLNLTSTFLRKNQ 66 Query: 83 CSEIFLVADKTEKAGEY--SVTYDGS-NTFTILKTDYDNY-IMIHLINKKDGETFQLMEL 138 +V G Y S + GS ++ ++++ +YD Y ++ K G+ F++ L Sbjct: 67 AETKIMVLQPAGAPGHYTYSSPHSGSIHSVSVVEANYDEYALLFSRGTKGPGQDFRMATL 126 Query: 139 YGREPDLSSDIKEKFAQLSEEHGIVRENIIDLTNANRCLE 178 Y R L ++KEKF S+ G+ E+I+ L ++ ++ Sbjct: 127 YSRTQTLKDELKEKFTTFSKAQGLTEEDIVFLPQPDKAIQ 166 >2K23-A nrPDB Length = 178 Score = 53.1 bits (126), Expect = 6e-08, Method: Compositional matrix adjust. Identities = 34/163 (20%), Positives = 74/163 (45%), Gaps = 10/163 (6%) Query: 24 SMERNFNVEKINGEWYTIMLATDKREKIEEHGSMRVFVEYIHVLE--NSLALKFHIIINE 81 ++ F E+ G W+ + LA + +K E S I+ L+ NS + ++ + Sbjct: 17 PLQPGFWTERFQGRWFVVGLAGNAVQK--ERQSRFTMYSTIYELQEDNSYNVTSILVRGQ 74 Query: 82 ECSEIFLVADKTEKAGEYSV----TYDGSNTF--TILKTDYDNYIMIHLINKKDGETFQL 135 C + + G++++ +Y ++ + TDYD + M+ + + + Sbjct: 75 GCRYWIRTFVPSSRPGQFTLGNIHSYPQIQSYDVQVADTDYDQFAMVFFQKTSENKQYFK 134 Query: 136 MELYGREPDLSSDIKEKFAQLSEEHGIVRENIIDLTNANRCLE 178 + LYGR LS ++KE+F ++ G+ NI+ ++C++ Sbjct: 135 VTLYGRTKGLSDELKERFVSFAKSLGLKDNNIVFSVPTDQCID 177 >1G85-A nrPDB Length = 159 Score = 52.8 bits (125), Expect = 7e-08, Method: Compositional matrix adjust. Identities = 39/152 (25%), Positives = 76/152 (50%), Gaps = 6/152 (3%) Query: 22 ASSMERNFNVEKINGEWYTIMLATDKREKIEEHGSMRVFVEYIHVLENSLALKFHIIINE 81 A E N+ +++G W T+ + + EKI+E+G R + + + + F+ + Sbjct: 1 AQEEEAEQNLSELSGPWRTVYIGSTNPEKIQENGPFRTYFRELVFDDEKGTVDFYFSVKR 60 Query: 82 E--CSEIFLVADKTEKAGEYSVTYDGSNTFTILKTDYDNYIMIHLIN-KKDGETFQLMEL 138 + + + A K + G Y Y+G N F I+ +++ H IN K G+T +L L Sbjct: 61 DGKWKNVHVKATKQDD-GTYVADYEGQNVFKIVSLSR-THLVAHNINVDKHGQTTELTGL 118 Query: 139 YGREPDLSSDIKEKFAQLSEEHGIVRENIIDL 170 + + D+ EKF +L+E+ GI ++N+++ Sbjct: 119 FVKLNVEDEDL-EKFWKLTEDKGIDKKNVVNF 149 >4QAE-A nrPDB Length = 188 Score = 52.8 bits (125), Expect = 8e-08, Method: Compositional matrix adjust. Identities = 39/175 (22%), Positives = 88/175 (50%), Gaps = 12/175 (6%) Query: 14 LVCVHAEEASSMERNFNVEKINGEWYTIMLATDKREKIEEHGSMRVFVEYIHVLENSLAL 73 L+ +++NF + +G+WY + LA ++ + E+ M+++ I+ LE + Sbjct: 7 LIPAPPLSKVPLQQNFQDNQFHGKWYVVGLAGNEVLR-EDKDPMKMWAT-IYELEEDKSY 64 Query: 74 KFHIIIN--EECSEIFLVADKTEKAGEYSV----TYDG--SNTFTILKTDYDNYIMIHL- 124 I++ E+C +F + GE+++ + G S ++ T+Y+ + M+ Sbjct: 65 NVTIVMPLAEKCEYLFQTFVPGSQPGEFTLGGIKSGPGRTSGLVRVVSTNYNQHAMVFFK 124 Query: 125 INKKDGETFQLMELYGREPDLSSDIKEKFAQLSEEHGIVRENIIDLTNANRCLEA 179 + ++ E F + LYGR +L+S++KE F + S+ G+ +I+ ++C++ Sbjct: 125 VVWQNREVF-WVTLYGRTKELTSELKENFIRFSKSLGLPENHIVFPVPIDQCIDG 178 >1EXS-A nrPDB Length = 160 Score = 50.4 bits (119), Expect = 5e-07, Method: Compositional matrix adjust. Identities = 30/135 (22%), Positives = 65/135 (48%), Gaps = 2/135 (1%) Query: 21 EASSMERNFNVEKINGEWYTIMLATDKREKIEEHGS-MRVFVEYI-HVLENSLALKFHII 78 E + + + +K+ G W+T+ +A ++ S ++ +VE + E L + Sbjct: 2 EVTPIMTELDTQKVAGTWHTVAMAVSDVSLLDAKSSPLKAYVEGLKPTPEGDLEILLQKR 61 Query: 79 INEECSEIFLVADKTEKAGEYSVTYDGSNTFTILKTDYDNYIMIHLINKKDGETFQLMEL 138 N++C++ L+A KT+ + + N +L TDYD+++++ + N E + + Sbjct: 62 ENDKCAQEVLLAKKTDIPAVFKINALDENQLFLLDTDYDSHLLLCMENSASPEHSLVCQS 121 Query: 139 YGREPDLSSDIKEKF 153 R ++ I+EKF Sbjct: 122 LARTLEVDDQIREKF 136 >4R0B-A nrPDB Length = 169 Score = 50.1 bits (118), Expect = 6e-07, Method: Compositional matrix adjust. Identities = 26/101 (25%), Positives = 55/101 (54%), Gaps = 2/101 (1%) Query: 26 ERNFNVEKINGEWYTIMLATDKREKIEE-HGSMRVFV-EYIHVLENSLALKFHIIINEEC 83 +++ + K+ G W+++ +AT++ + +RV + + E++L + H N C Sbjct: 6 KQDLELPKLAGTWHSMAMATNEISLMATLKAPLRVHITSLLPTPEDNLEIVLHRWENNSC 65 Query: 84 SEIFLVADKTEKAGEYSVTYDGSNTFTILKTDYDNYIMIHL 124 E ++ +KTE ++ + Y +N T+L TDYDN++ + L Sbjct: 66 VEKKVLGEKTENPKKFKINYTVANEATLLDTDYDNFLFLCL 106 >5N47-A nrPDB Length = 188 Score = 47.0 bits (110), Expect = 5e-06, Method: Compositional matrix adjust. Identities = 34/177 (19%), Positives = 80/177 (45%), Gaps = 16/177 (9%) Query: 14 LVCVHAEEASSMERNFNVEKINGEWYTIMLATDKREKIEEHGSMRVFVEYIHVLE----- 68 L+ +++NF + +G+WY + A + + E R I+ L+ Sbjct: 7 LIPAPPLSKVPLQQNFQDNQFHGKWYVVGEAGNSL--LREDKDPRKMYATIYELKEDKSY 64 Query: 69 NSLALKFHIIINEECSEIFLVADKTEKAGEYSV----TYDGSNTF--TILKTDYDNYIMI 122 N +++F +++C + + GE+++ + G +F ++ T+Y+ + M+ Sbjct: 65 NVTSVRFR---SKKCHYLIRTFVPGSQPGEFTLGLIKSKPGHTSFLVRVVSTNYNQHAMV 121 Query: 123 HLINKKDGETFQLMELYGREPDLSSDIKEKFAQLSEEHGIVRENIIDLTNANRCLEA 179 + + LYGR +L+S++KE F + S+ G+ +I+ ++C++ Sbjct: 122 FFKTVAQNREYFFITLYGRTKELTSELKENFIRFSKSLGLPENHIVFPVPIDQCIDG 178 >5MHH-A nrPDB Length = 188 Score = 46.2 bits (108), Expect = 8e-06, Method: Compositional matrix adjust. Identities = 32/173 (18%), Positives = 79/173 (45%), Gaps = 8/173 (4%) Query: 14 LVCVHAEEASSMERNFNVEKINGEWYTIMLATDKREKIEEHGSMRVFVEYIHVLEN-SLA 72 L+ +++NF + +G+WY + A + + E+ ++F + E+ S Sbjct: 7 LIPAPPLSKVPLQQNFQDNQFHGKWYVVGFAGNAILR-EDKDPQKMFATIYELKEDKSYN 65 Query: 73 LKFHIIINEECSEIFLVADKTEKAGEYSV----TYDGSNTF--TILKTDYDNYIMIHLIN 126 + + ++C + GE+++ +Y G ++ ++ T+Y+ + M+ Sbjct: 66 VTSVLFRKKKCDYWIRTFVPGSQPGEFTLGNIKSYPGLTSYLVRVVSTNYNQHAMVFFKW 125 Query: 127 KKDGETFQLMELYGREPDLSSDIKEKFAQLSEEHGIVRENIIDLTNANRCLEA 179 + + LYGR +L+S++KE F + S+ G+ +I+ ++C++ Sbjct: 126 VSQNREYFNITLYGRTKELTSELKENFIRFSKSLGLPENHIVFPVPIDQCIDG 178 >1EPB-A nrPDB Length = 164 Score = 46.2 bits (108), Expect = 9e-06, Method: Compositional matrix adjust. Identities = 34/153 (22%), Positives = 66/153 (43%), Gaps = 1/153 (0%) Query: 27 RNFNVEKINGEWYTIMLATDKREKIEEHGSMRVFVEYIHVLENSLALKFHIIINEECSEI 86 ++F++ K G WY I A+ H ++ + + EN LAL + C Sbjct: 4 KDFDISKFLGFWYEIAFASKMGTPGLAHKEEKMGAMVVELKENLLALTTTYYSEDHCVLE 63 Query: 87 FLVADKTEKAGEYSVT-YDGSNTFTILKTDYDNYIMIHLINKKDGETFQLMELYGREPDL 145 + A + + ++ VT G + TDY Y +I + + G + M+LY R D Sbjct: 64 KVTATEGDGPAKFQVTRLSGKKEVVVEATDYLTYAIIDITSLVAGAVHRTMKLYSRSLDD 123 Query: 146 SSDIKEKFAQLSEEHGIVRENIIDLTNANRCLE 178 + + F +++ +HG ++ L + C++ Sbjct: 124 NGEALYNFRKITSDHGFSETDLYILKHDLTCVK 156 >5N48-A nrPDB Length = 188 Score = 45.1 bits (105), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 32/172 (18%), Positives = 75/172 (43%), Gaps = 6/172 (3%) Query: 14 LVCVHAEEASSMERNFNVEKINGEWYTIMLATDKREKIEEHGSMRVFVEYIHVLENSLAL 73 L+ +++NF + +G+WY + A + R + ++ + V Y + S + Sbjct: 7 LIPAPPLSKVPLQQNFQDNQFHGKWYVVGRAGNMRLREDKDPAKMVATIYELKEDKSYNV 66 Query: 74 KFHIIINEECSEIFLVADKTEKAGEY------SVTYDGSNTFTILKTDYDNYIMIHLINK 127 + ++C + + GE+ S S ++ T+Y+ + M+ + Sbjct: 67 TKVMFQRKKCKYMINTFVPGSQPGEFTLGAIKSPPGPTSTLVRVVSTNYNQHAMVFFKHV 126 Query: 128 KDGETFQLMELYGREPDLSSDIKEKFAQLSEEHGIVRENIIDLTNANRCLEA 179 + + LYGR +L+S++KE F + S+ G+ +I+ ++C++ Sbjct: 127 FQNREYFHITLYGRTKELTSELKENFIRFSKSLGLPENHIVFPVPIDQCIDG 178 >3DTQ-A nrPDB Length = 186 Score = 44.7 bits (104), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 33/177 (18%), Positives = 79/177 (44%), Gaps = 16/177 (9%) Query: 14 LVCVHAEEASSMERNFNVEKINGEWYTIMLATDKREKIEEHGSMRVFVEYIHVLE----- 68 L+ +++NF + +G+WY + A + + E + I+ L+ Sbjct: 7 LIPAPPLSKVPLQQNFQDNQFHGKWYQVGRAGN--AALREDKDPQKMTAQIYELKEDKSY 64 Query: 69 NSLALKFHIIINEECSEIFLVADKTEKAGEYSV----TYDGSNTF--TILKTDYDNYIMI 122 N A++F ++C + + GE+++ +Y G ++ ++ T+Y+ + M+ Sbjct: 65 NVTAVRFR---KKKCDYATMTFVPGSQPGEFTLGNIKSYPGLTSYLVRVVSTNYNQHAMV 121 Query: 123 HLINKKDGETFQLMELYGREPDLSSDIKEKFAQLSEEHGIVRENIIDLTNANRCLEA 179 + + L GR +L+S++KE F + S+ G+ +I+ ++C++ Sbjct: 122 FFKKVSQNREYFSITLLGRTKELASELKENFIRFSKSLGLPENHIVFPVPIDQCIDG 178 >4MVK-A nrPDB Length = 188 Score = 43.9 bits (102), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 35/177 (19%), Positives = 85/177 (48%), Gaps = 16/177 (9%) Query: 14 LVCVHAEEASSMERNFNVEKINGEWYTIMLATDKREKIEEHGSMRVFVEYIHVLE----N 69 L+ +++NF + +G+WY + +A +K + E+ +++ + E N Sbjct: 7 LIPAPPLSKVPLQQNFQDNQFHGKWYVVGVAGNKSLR-EDKDPWKMYATIYELKEDKSYN 65 Query: 70 SLALKFHIIINEECSEIFLVADKTEKAGEYSV----TYDG--SNTFTILKTDYDNYIMIH 123 ++ F ++C + GE+++ + G S ++ T+Y+ + M+ Sbjct: 66 VTSVGFGT---KKCHYKIRTFVPGSQPGEFTLGRIKSRPGRTSALVRVVSTNYNQHAMVF 122 Query: 124 L-INKKDGETFQLMELYGREPDLSSDIKEKFAQLSEEHGIVRENIIDLTNANRCLEA 179 + +++ E+F + LYGR +L+S++KE F + S+ G+ +I+ ++C++ Sbjct: 123 FKVVQQNRESFNIT-LYGRTKELTSELKENFIRFSKSLGLPENHIVFPVPIDQCIDG 178 >4IAX-A nrPDB Length = 188 Score = 43.1 bits (100), Expect = 7e-05, Method: Compositional matrix adjust. Identities = 32/175 (18%), Positives = 79/175 (45%), Gaps = 12/175 (6%) Query: 14 LVCVHAEEASSMERNFNVEKINGEWYTIMLATDKREKIEEHGSMRVFVEYIHVLENSL-- 71 L+ +++NF + +G+WY + A + ++ + Y + S Sbjct: 7 LIPAPPLSKVPLQQNFQDNQFHGKWYQVGRAGNAAPPMDPELLLLTAQTYELKEDKSYDV 66 Query: 72 -ALKFHIIINEECSEIFLVADKTEKAGEYSV----TYDGSNTF--TILKTDYDNYIMIHL 124 A++F + E + F+ + + GE+++ Y G ++ ++ T+Y+ + M+ Sbjct: 67 TAVRFRKKMCEYLTMTFV---PSPQPGEFTLGNIKNYPGLTSYFVRVVSTNYNQHAMVFF 123 Query: 125 INKKDGETFQLMELYGREPDLSSDIKEKFAQLSEEHGIVRENIIDLTNANRCLEA 179 + + + L GR +L+S++KE F + S+ G+ +I+ ++C++ Sbjct: 124 KKVQQNREYFSISLLGRTKELASELKENFIRFSKSLGLPENHIVFPVPIDQCIDG 178 >5NKN-A nrPDB Length = 174 Score = 43.1 bits (100), Expect = 7e-05, Method: Compositional matrix adjust. Identities = 31/173 (17%), Positives = 80/173 (46%), Gaps = 8/173 (4%) Query: 14 LVCVHAEEASSMERNFNVEKINGEWYTIMLATDKREKIEEHGSMRVFVEYIHVLEN-SLA 72 L+ +++NF + +G+WY + +A + + E+ +++ + E+ S Sbjct: 3 LIPAPPLSKVPLQQNFQDNQFHGKWYVVGVAGNGFLR-EDKDPIKMAATIYELKEDKSYN 61 Query: 73 LKFHIIINEECSEIFLVADKTEKAGEYSV----TYDGSNTF--TILKTDYDNYIMIHLIN 126 + F ++C + + GE+++ + G ++ ++ T+Y+ + M+ Sbjct: 62 VTFQKFPMKKCQYMTDTLVPGSQPGEFTLGNIKSEPGYTSWLVRVVSTNYNQHAMVFFKA 121 Query: 127 KKDGETFQLMELYGREPDLSSDIKEKFAQLSEEHGIVRENIIDLTNANRCLEA 179 + + LYGR +L+S++KE F + S+ G+ +I+ ++C++ Sbjct: 122 VQQNREDFFITLYGRTKELTSELKENFIRFSKSLGLPENHIVFPVPIDQCIDG 174 >5JR8-A nrPDB Length = 178 Score = 43.1 bits (100), Expect = 7e-05, Method: Compositional matrix adjust. Identities = 29/151 (19%), Positives = 72/151 (47%), Gaps = 8/151 (5%) Query: 36 GEWYTIMLATDKREKIEEHGSMRVFVEYIHVLEN-SLALKFHIIINEECSEIFLVADKTE 94 G+WY + LA + + E+ +++ + E+ S + + ++ C Sbjct: 29 GKWYVVGLAGNAILR-EDEDPQKMYATIYELKEDKSYNVTSVLFRDDGCDYWIRTFVPGC 87 Query: 95 KAGEYSV----TYDGSNTF--TILKTDYDNYIMIHLINKKDGETFQLMELYGREPDLSSD 148 + GE+++ +Y G ++ ++ T+Y+ + M+ + + + LYGR +L+S+ Sbjct: 88 QPGEFTLGNIQSYPGLTSYLVRVVSTNYNQFAMVFFKKVSQNQEYFKITLYGRTKELTSE 147 Query: 149 IKEKFAQLSEEHGIVRENIIDLTNANRCLEA 179 ++E F + S+ G+ NI+ ++C++ Sbjct: 148 LQENFIRFSKSLGLPENNIVFPVPIDQCIDG 178 >6GQZ-A nrPDB Length = 174 Score = 42.7 bits (99), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 31/173 (17%), Positives = 79/173 (45%), Gaps = 8/173 (4%) Query: 14 LVCVHAEEASSMERNFNVEKINGEWYTIMLATDKREKIEEHGSMRVFVEYIHVLENSLAL 73 L+ +++NF + +G+WY + A + +++ E+ ++ + E+ Sbjct: 3 LIPAPPLSKVPLQQNFQDNQFHGKWYVVGFAENIQQR-EDKDPPKMIATIYELKEDKSYN 61 Query: 74 KFHIIIN-EECSEIFLVADKTEKAGEYSV----TYDGSNTF--TILKTDYDNYIMIHLIN 126 ++ N E+C+ + GE+++ + G ++ ++ T+Y+ + M+ Sbjct: 62 VTNVASNWEKCTYRIKTFVPGSQPGEFTLGEIKSRPGMTSYLVRVVSTNYNQHAMVFFKT 121 Query: 127 KKDGETFQLMELYGREPDLSSDIKEKFAQLSEEHGIVRENIIDLTNANRCLEA 179 + LYGR +L+S++KE F + S+ G+ +I+ ++C++ Sbjct: 122 VVQNREKFWITLYGRTKELTSELKENFIRFSKSLGLPENHIVFPVPIDQCIDG 174 >3EYC-A nrPDB Length = 162 Score = 42.4 bits (98), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 31/147 (21%), Positives = 70/147 (47%), Gaps = 4/147 (2%) Query: 31 VEKINGEWYTIMLATDKREKIEEHGSMRVFVEYIHVLENS-LALKFHIIINEECSEIFLV 89 ++ ++G WY + D+ + E V + LE L K ++I+ C E+ V Sbjct: 6 IQDVSGTWYLKAMTVDR--EFPEMNLESVTPMTLTTLEGGNLEAKVTMLISGRCQEVKAV 63 Query: 90 ADKTEKAGEYSVTYDGSNTFTILKTDYDNYIMIHLINKKDGETFQLMELYGREPDLSSDI 149 +KT++ G+Y+ G + I+++ ++ + + + G+ + ++L GR+P + + Sbjct: 64 LEKTDEPGKYTAD-GGKHVAYIIRSHVKDHYIFYSEGELHGKPVRGVKLVGRDPKNNLEA 122 Query: 150 KEKFAQLSEEHGIVRENIIDLTNANRC 176 E F + + G+ E+I+ + C Sbjct: 123 LEDFEKAAGARGLSTESILIPRQSETC 149 >4GH7-A nrPDB Length = 188 Score = 42.0 bits (97), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 35/179 (19%), Positives = 85/179 (47%), Gaps = 20/179 (11%) Query: 14 LVCVHAEEASSMERNFNVEKINGEWYTIMLATDKREKIEEHGSMRVFVEYIHVLE----- 68 L+ +++NF + +G+WY + A + + E R I+ L+ Sbjct: 7 LIPAPPLSKVPLQQNFQDNQFHGKWYVVGKAGN--HDLREDKDPRKMQATIYELKEDKSY 64 Query: 69 NSLALKFHIIINEECSEIFLVADKTEKAGEYSV----TYDGSNTF--TILKTDYDNYIMI 122 N ++F ++++C+ + GE+++ ++ G ++ ++ T+Y+ + M+ Sbjct: 65 NVTNVRF---VHKKCNYRIWTFVPGSQPGEFTLGNIKSWPGLTSWLVRVVSTNYNQHAMV 121 Query: 123 HLINKKDGETFQLME--LYGREPDLSSDIKEKFAQLSEEHGIVRENIIDLTNANRCLEA 179 K+ + +L E LYGR +L++++KE F + S+ G+ +I+ ++C++ Sbjct: 122 FF--KRVYQNRELFEITLYGRTKELTNELKENFIRFSKSLGLPENHIVFPVPIDQCIDG 178 >4RUN-A nrPDB Length = 161 Score = 41.2 bits (95), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 32/147 (21%), Positives = 62/147 (42%), Gaps = 3/147 (2%) Query: 32 EKINGEWYTIMLATDKREKIEEHGSMRVFVEYIHVLENSLALKFHIIINEECSEIFLVAD 91 E I G WY + DK + V+ + +L F + + C + ++ Sbjct: 8 EDITGTWYVKAMVVDKDFPEDRRPRKVSPVKVTALGGGNLEATFTFMREDRCIQKKILMR 67 Query: 92 KTEKAGEYSVTYDGSNTFTILK-TDYDNYIMIHLINKKDGETFQLMELYGREPDLSSDIK 150 KTE+ G++S Y G + + D+Y+ ++ G + + L GR P+ + + Sbjct: 68 KTEEPGKFSA-YGGRKLIYLQELPGTDDYVFYSKDQRRGGLRY-MGNLVGRNPNTNLEAL 125 Query: 151 EKFAQLSEEHGIVRENIIDLTNANRCL 177 E+F +L + G+ E+I C+ Sbjct: 126 EEFKKLVQHKGLSEEDIFMPLQTGSCV 152 >4MVL-A nrPDB Length = 188 Score = 40.8 bits (94), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 36/181 (19%), Positives = 79/181 (43%), Gaps = 24/181 (13%) Query: 14 LVCVHAEEASSMERNFNVEKINGEWYTIMLATDKREKIEEHGSMRVFVEYIHVLE----N 69 L+ +++NF + +G+WY + A + + E+ ++++ + E N Sbjct: 7 LIPAPPLSKVPLQQNFQDNQFHGKWYVVGAAGNVLLR-EDKDPLKMYATIYELKEDKSYN 65 Query: 70 SLALKFH----------IIINEECSEIFLVADKTEKAGEYSVTYDGSNTFTILKTDYDNY 119 ++ F + + E L K+E G S ++ T+Y+ + Sbjct: 66 VTSVGFDDKKCLYKIRTFVPGSQPGEFTLGRIKSEPGGT-------SWLVRVVSTNYNQH 118 Query: 120 IMIHLIN-KKDGETFQLMELYGREPDLSSDIKEKFAQLSEEHGIVRENIIDLTNANRCLE 178 M+ ++ ETF + LYGR +L+S++KE F + S+ G+ +I+ ++C++ Sbjct: 119 AMVFFKEVAQNRETFNIT-LYGRTKELTSELKENFIRFSKSLGLPENHIVFPVPIDQCID 177 Query: 179 A 179 Sbjct: 178 G 178 >1BBP-A nrPDB Length = 173 Score = 30.8 bits (68), Expect = 0.35, Method: Compositional matrix adjust. Identities = 25/100 (25%), Positives = 43/100 (43%), Gaps = 10/100 (10%) Query: 28 NFNVEKINGEWYTIMLATDKREKIEEHGSMRVFVEYIHVLENSLALKFHIIINEEC---S 84 NF+ +G+W+ + + EK + G + EY ++ +H+I +E Sbjct: 16 NFDWSNYHGKWWEVAKYPNSVEKYGKCG----WAEYTPEGKSVKVSNYHVIHGKEYFIEG 71 Query: 85 EIFLVADKTEKAGEYSVTYDG---SNTFTILKTDYDNYIM 121 + V D + +TY G N F +L TD NYI+ Sbjct: 72 TAYPVGDSKIGKIYHKLTYGGVTKENVFNVLSTDNKNYII 111 >1GKA-B nrPDB Length = 174 Score = 30.4 bits (67), Expect = 0.39, Method: Compositional matrix adjust. Identities = 25/164 (15%), Positives = 64/164 (39%), Gaps = 22/164 (13%) Query: 26 ERNFNVEKINGEWYTIMLATDKREKI------------EEHGSMRVFVEYIHVLENSLAL 73 + NF++ + G WY + + + + ++G +V + + L + Sbjct: 18 QDNFDLRRYAGRWYQTHIIENAYQPVTRCIHSNYEYSTNDYG-FKVTTAGFNPNDEYLKI 76 Query: 74 KFHIIINEECSEIFLVADKTEKAGEYSVTYDGSNTFTILKTDYDNYIMIHLINKKDGETF 133 F + +E ++ D ++ Y+ +++TDY+ Y ++ D Sbjct: 77 DFKVYPTKEFPAAHMLIDA---PSVFAAPYE------VIETDYETYSCVYSCITTDNYKS 127 Query: 134 QLMELYGREPDLSSDIKEKFAQLSEEHGIVRENIIDLTNANRCL 177 + ++ R P S EK A + ++G+ + +++ C+ Sbjct: 128 EFAFVFSRTPQTSGPAVEKTAAVFNKNGVEFSKFVPVSHTAECV 171 >3CQR-A nrPDB Length = 185 Score = 28.1 bits (61), Expect = 2.5, Method: Compositional matrix adjust. Identities = 9/21 (42%), Positives = 14/21 (66%) Query: 19 AEEASSMERNFNVEKINGEWY 39 A + S + +NFN+ NG+WY Sbjct: 8 APDPSVLVQNFNISDFNGKWY 28 >1JYJ-A nrPDB Length = 183 Score = 27.7 bits (60), Expect = 2.6, Method: Compositional matrix adjust. Identities = 28/151 (18%), Positives = 63/151 (41%), Gaps = 13/151 (8%) Query: 28 NFNVEKINGEWYTIMLATDKREKIEEHGSMRVFVEYIHVLENSLALKFHIIIN-EECSEI 86 NF+ + +G WY + + ++++ V+ + + + ++ N + C+++ Sbjct: 15 NFDKARFSGTWYAMAKKDPEGLFLQDNIVAEFSVDETGQMSATAKGRVRLLNNLDVCADM 74 Query: 87 FLVADKTEKAGEYSVTYDGSNTF--------TILKTDYDNYIM---IHLINKKDGETFQL 135 TE ++ + Y G +F I+ TDYD Y + L+N Sbjct: 75 VGTFTDTEDPAKFKMKYHGVASFLQKGNDDHWIVDTDYDTYAVQYSCRLLNLDGTCADSY 134 Query: 136 MELYGREPD-LSSDIKEKFAQLSEEHGIVRE 165 ++ R+P+ L + ++ Q EE + R+ Sbjct: 135 SFVFSRDPNGLPPEAQKIVRQRQEELCLARQ 165 >4PSQ-B nrPDB Length = 212 Score = 27.7 bits (60), Expect = 2.6, Method: Compositional matrix adjust. Identities = 28/151 (18%), Positives = 63/151 (41%), Gaps = 13/151 (8%) Query: 28 NFNVEKINGEWYTIMLATDKREKIEEHGSMRVFVEYIHVLENSLALKFHIIINEE-CSEI 86 NF+ + +G WY + + ++++ V+ + + + ++ N + C+++ Sbjct: 43 NFDKARFSGTWYAMAKKDPEGLFLQDNIVAEFSVDETGQMSATAKGRVRLLNNWDVCADM 102 Query: 87 FLVADKTEKAGEYSVTYDGSNTF--------TILKTDYDNYIM---IHLINKKDGETFQL 135 TE ++ + Y G +F I+ TDYD Y + L+N Sbjct: 103 VGTFTDTEDPAKFKMKYWGVASFLQKGNDDHWIVDTDYDTYAVQYSCRLLNLDGTCADSY 162 Query: 136 MELYGREPD-LSSDIKEKFAQLSEEHGIVRE 165 ++ R+P+ L + ++ Q EE + R+ Sbjct: 163 SFVFSRDPNGLPPEAQKIVRQRQEELCLARQ 193 >4AC8-A nrPDB Length = 323 Score = 27.7 bits (60), Expect = 2.9, Method: Compositional matrix adjust. Identities = 34/127 (26%), Positives = 56/127 (44%), Gaps = 16/127 (12%) Query: 55 GSMRVFVEYIHVLENSLALKFHIIINEECSEIFLVADKTE---KAGEYSVTYDGSNTFTI 111 +R V Y H++E LAL + ++ C E ++ E + G+ + TFT Sbjct: 163 AQVRASVTYNHIVEGMLALTGYYAWHKICVERAILPGMQELVRRIGDDERRHMAWGTFTC 222 Query: 112 LK---TDYDNYIMIHL-INKKDGETFQLME----LYGREP--DLSSDIKEKFAQLSEEHG 161 + D N+ + +N+ +L+E LYG +P DLS K+ F Q S + G Sbjct: 223 RRHVAADDANWTVFETRMNELIPLALRLIEEGFALYGDQPPFDLS---KDDFLQYSTDKG 279 Query: 162 IVRENII 168 + R I Sbjct: 280 MRRFGTI 286 >1DMG-A nrPDB Length = 225 Score = 26.9 bits (58), Expect = 4.4, Method: Compositional matrix adjust. Identities = 14/31 (45%), Positives = 18/31 (58%), Gaps = 2/31 (6%) Query: 88 LVADKT--EKAGEYSVTYDGSNTFTILKTDY 116 ++AD K GE +V DG N F +LK DY Sbjct: 179 IIADNPNNSKNGEKAVRIDGLNVFDMLKYDY 209 >1G0D-A nrPDB Length = 695 Score = 26.9 bits (58), Expect = 4.7, Method: Composition-based stats. Identities = 11/41 (26%), Positives = 20/41 (48%) Query: 65 HVLENSLALKFHIIINEECSEIFLVADKTEKAGEYSVTYDG 105 H++E + + FH++ N C + + K EY + DG Sbjct: 120 HIVERADKISFHMLFNPWCRDDMVYLPDESKLQEYVMNEDG 160 >1RKQ-A nrPDB Length = 282 Score = 26.2 bits (56), Expect = 8.2, Method: Compositional matrix adjust. Identities = 17/64 (26%), Positives = 34/64 (53%), Gaps = 11/64 (17%) Query: 94 EKAGEYSVTYDG------SNTFTILKT--DYDNYIMIHLINKKDGETFQLME---LYGRE 142 E+ G+Y +TY+G ++ T+ +T YD+Y + ++++ G F ++ LY Sbjct: 62 EQPGDYCITYNGALVQKAADGSTVAQTALSYDDYRFLEKLSREVGSHFHALDRTTLYTAN 121 Query: 143 PDLS 146 D+S Sbjct: 122 RDIS 125 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 5MHH-A nrPDB 236 4e-63 5N47-A nrPDB 232 9e-62 4QAE-A nrPDB 230 3e-61 4MVK-A nrPDB 229 3e-61 4MVL-A nrPDB 229 5e-61 5N48-A nrPDB 229 6e-61 3DTQ-A nrPDB 228 1e-60 5NKN-A nrPDB 226 4e-60 4GH7-A nrPDB 224 2e-59 6GQZ-A nrPDB 219 5e-58 4IAX-A nrPDB 218 1e-57 5JR8-A nrPDB 206 4e-54 2L9C-A nrPDB 202 7e-53 3KFG-A nrPDB 197 3e-51 2K23-A nrPDB 192 7e-50 5X7Y-A nrPDB 191 1e-49 3U9P-C nrPDB 190 2e-49 1EW3-A nrPDB 175 7e-45 1GM6-A nrPDB 174 2e-44 2R73-A nrPDB 169 6e-43 2E4J-A nrPDB 162 7e-41 3O22-A nrPDB 162 7e-41 3L4R-A nrPDB 157 2e-39 1JZU-A nrPDB 149 8e-37 3SAO-A nrPDB 147 2e-36 1E5P-A nrPDB 137 2e-33 1EPB-A nrPDB 136 6e-33 1E06-A nrPDB 134 2e-32 4RUN-A nrPDB 125 9e-30 3EYC-A nrPDB 122 7e-29 4WFU-A nrPDB 122 7e-29 1G85-A nrPDB 118 9e-28 1EXS-A nrPDB 117 3e-27 4R0B-A nrPDB 105 2e-23 Sequences not found previously or not previously below threshold: 4QAF-A nrPDB 91 3e-19 2RD7-C nrPDB 74 3e-14 1IIU-A nrPDB 55 2e-08 4PSQ-B nrPDB 51 3e-07 1JYJ-A nrPDB 49 8e-07 1BBP-A nrPDB 48 2e-06 1GKA-B nrPDB 48 3e-06 1FEM-A nrPDB 47 5e-06 1KXO-A nrPDB 47 6e-06 3MBT-A nrPDB 45 2e-05 2ACO-A nrPDB 45 2e-05 1N0S-A nrPDB 42 2e-04 3KQ0-A nrPDB 42 2e-04 2HZQ-A nrPDB 38 0.002 1Z24-A nrPDB 38 0.002 3EBK-A nrPDB 35 0.025 3APW-A nrPDB 34 0.035 1OBQ-A nrPDB 34 0.038 3CQR-A nrPDB 33 0.091 1YRZ-A nrPDB 32 0.20 2WM5-A nrPDB 30 0.70 1AJ8-A nrPDB 29 1.4 5H9K-A nrPDB 28 2.2 2BIG-A nrPDB 28 2.4 2VYO-A nrPDB 27 3.5 3LVG-A nrPDB 27 4.6 1B89-A nrPDB 27 4.8 1UYP-A nrPDB 27 4.8 4MNU-A nrPDB 26 8.7 >5MHH-A nrPDB Length = 188 Score = 236 bits (603), Expect = 4e-63, Method: Composition-based stats. Identities = 32/173 (18%), Positives = 79/173 (45%), Gaps = 8/173 (4%) Query: 14 LVCVHAEEASSMERNFNVEKINGEWYTIMLATDKREKIEEHGSMRVFVEYIHVLEN-SLA 72 L+ +++NF + +G+WY + A + + E+ ++F + E+ S Sbjct: 7 LIPAPPLSKVPLQQNFQDNQFHGKWYVVGFAGNAILR-EDKDPQKMFATIYELKEDKSYN 65 Query: 73 LKFHIIINEECSEIFLVADKTEKAGEYSV----TYDGSNTF--TILKTDYDNYIMIHLIN 126 + + ++C + GE+++ +Y G ++ ++ T+Y+ + M+ Sbjct: 66 VTSVLFRKKKCDYWIRTFVPGSQPGEFTLGNIKSYPGLTSYLVRVVSTNYNQHAMVFFKW 125 Query: 127 KKDGETFQLMELYGREPDLSSDIKEKFAQLSEEHGIVRENIIDLTNANRCLEA 179 + + LYGR +L+S++KE F + S+ G+ +I+ ++C++ Sbjct: 126 VSQNREYFNITLYGRTKELTSELKENFIRFSKSLGLPENHIVFPVPIDQCIDG 178 >5N47-A nrPDB Length = 188 Score = 232 bits (591), Expect = 9e-62, Method: Composition-based stats. Identities = 31/173 (17%), Positives = 79/173 (45%), Gaps = 8/173 (4%) Query: 14 LVCVHAEEASSMERNFNVEKINGEWYTIMLATDKREKIEEHGSMRVFVEYIHVLEN-SLA 72 L+ +++NF + +G+WY + A + + E+ +++ + E+ S Sbjct: 7 LIPAPPLSKVPLQQNFQDNQFHGKWYVVGEAGNSLLR-EDKDPRKMYATIYELKEDKSYN 65 Query: 73 LKFHIIINEECSEIFLVADKTEKAGEYSV----TYDGSNTF--TILKTDYDNYIMIHLIN 126 + +++C + + GE+++ + G +F ++ T+Y+ + M+ Sbjct: 66 VTSVRFRSKKCHYLIRTFVPGSQPGEFTLGLIKSKPGHTSFLVRVVSTNYNQHAMVFFKT 125 Query: 127 KKDGETFQLMELYGREPDLSSDIKEKFAQLSEEHGIVRENIIDLTNANRCLEA 179 + + LYGR +L+S++KE F + S+ G+ +I+ ++C++ Sbjct: 126 VAQNREYFFITLYGRTKELTSELKENFIRFSKSLGLPENHIVFPVPIDQCIDG 178 >4QAE-A nrPDB Length = 188 Score = 230 bits (586), Expect = 3e-61, Method: Composition-based stats. Identities = 34/173 (19%), Positives = 82/173 (47%), Gaps = 8/173 (4%) Query: 14 LVCVHAEEASSMERNFNVEKINGEWYTIMLATDKREKIEEHGSMRVFVEYIHVLEN-SLA 72 L+ +++NF + +G+WY + LA ++ + E+ M+++ + E+ S Sbjct: 7 LIPAPPLSKVPLQQNFQDNQFHGKWYVVGLAGNEVLR-EDKDPMKMWATIYELEEDKSYN 65 Query: 73 LKFHIIINEECSEIFLVADKTEKAGEYSV----TYDGSNT--FTILKTDYDNYIMIHLIN 126 + + + E+C +F + GE+++ + G + ++ T+Y+ + M+ Sbjct: 66 VTIVMPLAEKCEYLFQTFVPGSQPGEFTLGGIKSGPGRTSGLVRVVSTNYNQHAMVFFKV 125 Query: 127 KKDGETFQLMELYGREPDLSSDIKEKFAQLSEEHGIVRENIIDLTNANRCLEA 179 + LYGR +L+S++KE F + S+ G+ +I+ ++C++ Sbjct: 126 VWQNREVFWVTLYGRTKELTSELKENFIRFSKSLGLPENHIVFPVPIDQCIDG 178 >4MVK-A nrPDB Length = 188 Score = 229 bits (585), Expect = 3e-61, Method: Composition-based stats. Identities = 31/173 (17%), Positives = 78/173 (45%), Gaps = 8/173 (4%) Query: 14 LVCVHAEEASSMERNFNVEKINGEWYTIMLATDKREKIEEHGSMRVFVEYIHVLEN-SLA 72 L+ +++NF + +G+WY + +A +K + E+ +++ + E+ S Sbjct: 7 LIPAPPLSKVPLQQNFQDNQFHGKWYVVGVAGNKSLR-EDKDPWKMYATIYELKEDKSYN 65 Query: 73 LKFHIIINEECSEIFLVADKTEKAGEYSV----TYDGSNT--FTILKTDYDNYIMIHLIN 126 + ++C + GE+++ + G + ++ T+Y+ + M+ Sbjct: 66 VTSVGFGTKKCHYKIRTFVPGSQPGEFTLGRIKSRPGRTSALVRVVSTNYNQHAMVFFKV 125 Query: 127 KKDGETFQLMELYGREPDLSSDIKEKFAQLSEEHGIVRENIIDLTNANRCLEA 179 + + LYGR +L+S++KE F + S+ G+ +I+ ++C++ Sbjct: 126 VQQNRESFNITLYGRTKELTSELKENFIRFSKSLGLPENHIVFPVPIDQCIDG 178 >4MVL-A nrPDB Length = 188 Score = 229 bits (584), Expect = 5e-61, Method: Composition-based stats. Identities = 31/173 (17%), Positives = 77/173 (44%), Gaps = 8/173 (4%) Query: 14 LVCVHAEEASSMERNFNVEKINGEWYTIMLATDKREKIEEHGSMRVFVEYIHVLEN-SLA 72 L+ +++NF + +G+WY + A + + E+ ++++ + E+ S Sbjct: 7 LIPAPPLSKVPLQQNFQDNQFHGKWYVVGAAGNVLLR-EDKDPLKMYATIYELKEDKSYN 65 Query: 73 LKFHIIINEECSEIFLVADKTEKAGEYSV----TYDG--SNTFTILKTDYDNYIMIHLIN 126 + +++C + GE+++ + G S ++ T+Y+ + M+ Sbjct: 66 VTSVGFDDKKCLYKIRTFVPGSQPGEFTLGRIKSEPGGTSWLVRVVSTNYNQHAMVFFKE 125 Query: 127 KKDGETFQLMELYGREPDLSSDIKEKFAQLSEEHGIVRENIIDLTNANRCLEA 179 + LYGR +L+S++KE F + S+ G+ +I+ ++C++ Sbjct: 126 VAQNRETFNITLYGRTKELTSELKENFIRFSKSLGLPENHIVFPVPIDQCIDG 178 >5N48-A nrPDB Length = 188 Score = 229 bits (584), Expect = 6e-61, Method: Composition-based stats. Identities = 31/173 (17%), Positives = 77/173 (44%), Gaps = 8/173 (4%) Query: 14 LVCVHAEEASSMERNFNVEKINGEWYTIMLATDKREKIEEHGSMRVFVEYIHVLEN-SLA 72 L+ +++NF + +G+WY + A + R + E+ ++ + E+ S Sbjct: 7 LIPAPPLSKVPLQQNFQDNQFHGKWYVVGRAGNMRLR-EDKDPAKMVATIYELKEDKSYN 65 Query: 73 LKFHIIINEECSEIFLVADKTEKAGEYSV------TYDGSNTFTILKTDYDNYIMIHLIN 126 + + ++C + + GE+++ S ++ T+Y+ + M+ + Sbjct: 66 VTKVMFQRKKCKYMINTFVPGSQPGEFTLGAIKSPPGPTSTLVRVVSTNYNQHAMVFFKH 125 Query: 127 KKDGETFQLMELYGREPDLSSDIKEKFAQLSEEHGIVRENIIDLTNANRCLEA 179 + + LYGR +L+S++KE F + S+ G+ +I+ ++C++ Sbjct: 126 VFQNREYFHITLYGRTKELTSELKENFIRFSKSLGLPENHIVFPVPIDQCIDG 178 >3DTQ-A nrPDB Length = 186 Score = 228 bits (581), Expect = 1e-60, Method: Composition-based stats. Identities = 30/173 (17%), Positives = 78/173 (45%), Gaps = 8/173 (4%) Query: 14 LVCVHAEEASSMERNFNVEKINGEWYTIMLATDKREKIEEHGSMRVFVEYIHVLEN-SLA 72 L+ +++NF + +G+WY + A + + E+ ++ + + E+ S Sbjct: 7 LIPAPPLSKVPLQQNFQDNQFHGKWYQVGRAGNAALR-EDKDPQKMTAQIYELKEDKSYN 65 Query: 73 LKFHIIINEECSEIFLVADKTEKAGEYSV----TYDGSNTF--TILKTDYDNYIMIHLIN 126 + ++C + + GE+++ +Y G ++ ++ T+Y+ + M+ Sbjct: 66 VTAVRFRKKKCDYATMTFVPGSQPGEFTLGNIKSYPGLTSYLVRVVSTNYNQHAMVFFKK 125 Query: 127 KKDGETFQLMELYGREPDLSSDIKEKFAQLSEEHGIVRENIIDLTNANRCLEA 179 + + L GR +L+S++KE F + S+ G+ +I+ ++C++ Sbjct: 126 VSQNREYFSITLLGRTKELASELKENFIRFSKSLGLPENHIVFPVPIDQCIDG 178 >5NKN-A nrPDB Length = 174 Score = 226 bits (576), Expect = 4e-60, Method: Composition-based stats. Identities = 31/173 (17%), Positives = 78/173 (45%), Gaps = 8/173 (4%) Query: 14 LVCVHAEEASSMERNFNVEKINGEWYTIMLATDKREKIEEHGSMRVFVEYIHVLEN-SLA 72 L+ +++NF + +G+WY + +A + E+ +++ + E+ S Sbjct: 3 LIPAPPLSKVPLQQNFQDNQFHGKWYVVGVAGN-GFLREDKDPIKMAATIYELKEDKSYN 61 Query: 73 LKFHIIINEECSEIFLVADKTEKAGEYSV----TYDGSNT--FTILKTDYDNYIMIHLIN 126 + F ++C + + GE+++ + G + ++ T+Y+ + M+ Sbjct: 62 VTFQKFPMKKCQYMTDTLVPGSQPGEFTLGNIKSEPGYTSWLVRVVSTNYNQHAMVFFKA 121 Query: 127 KKDGETFQLMELYGREPDLSSDIKEKFAQLSEEHGIVRENIIDLTNANRCLEA 179 + + LYGR +L+S++KE F + S+ G+ +I+ ++C++ Sbjct: 122 VQQNREDFFITLYGRTKELTSELKENFIRFSKSLGLPENHIVFPVPIDQCIDG 174 >4GH7-A nrPDB Length = 188 Score = 224 bits (570), Expect = 2e-59, Method: Composition-based stats. Identities = 29/173 (16%), Positives = 78/173 (45%), Gaps = 8/173 (4%) Query: 14 LVCVHAEEASSMERNFNVEKINGEWYTIMLATDKREKIEEHGSMRVFVEYIHVLEN-SLA 72 L+ +++NF + +G+WY + A + + E+ ++ + E+ S Sbjct: 7 LIPAPPLSKVPLQQNFQDNQFHGKWYVVGKAGNHDLR-EDKDPRKMQATIYELKEDKSYN 65 Query: 73 LKFHIIINEECSEIFLVADKTEKAGEYSV----TYDGSNT--FTILKTDYDNYIMIHLIN 126 + ++++C+ + GE+++ ++ G + ++ T+Y+ + M+ Sbjct: 66 VTNVRFVHKKCNYRIWTFVPGSQPGEFTLGNIKSWPGLTSWLVRVVSTNYNQHAMVFFKR 125 Query: 127 KKDGETFQLMELYGREPDLSSDIKEKFAQLSEEHGIVRENIIDLTNANRCLEA 179 + LYGR +L++++KE F + S+ G+ +I+ ++C++ Sbjct: 126 VYQNRELFEITLYGRTKELTNELKENFIRFSKSLGLPENHIVFPVPIDQCIDG 178 >6GQZ-A nrPDB Length = 174 Score = 219 bits (558), Expect = 5e-58, Method: Composition-based stats. Identities = 31/173 (17%), Positives = 79/173 (45%), Gaps = 8/173 (4%) Query: 14 LVCVHAEEASSMERNFNVEKINGEWYTIMLATDKREKIEEHGSMRVFVEYIHVLENSLAL 73 L+ +++NF + +G+WY + A + +++ E+ ++ + E+ Sbjct: 3 LIPAPPLSKVPLQQNFQDNQFHGKWYVVGFAENIQQR-EDKDPPKMIATIYELKEDKSYN 61 Query: 74 KFHIIIN-EECSEIFLVADKTEKAGEYSV----TYDGSNTF--TILKTDYDNYIMIHLIN 126 ++ N E+C+ + GE+++ + G ++ ++ T+Y+ + M+ Sbjct: 62 VTNVASNWEKCTYRIKTFVPGSQPGEFTLGEIKSRPGMTSYLVRVVSTNYNQHAMVFFKT 121 Query: 127 KKDGETFQLMELYGREPDLSSDIKEKFAQLSEEHGIVRENIIDLTNANRCLEA 179 + LYGR +L+S++KE F + S+ G+ +I+ ++C++ Sbjct: 122 VVQNREKFWITLYGRTKELTSELKENFIRFSKSLGLPENHIVFPVPIDQCIDG 174 >4IAX-A nrPDB Length = 188 Score = 218 bits (555), Expect = 1e-57, Method: Composition-based stats. Identities = 29/172 (16%), Positives = 75/172 (43%), Gaps = 6/172 (3%) Query: 14 LVCVHAEEASSMERNFNVEKINGEWYTIMLATDKREKIEEHGSMRVFVEYIHVLENSLAL 73 L+ +++NF + +G+WY + A + ++ + Y + S + Sbjct: 7 LIPAPPLSKVPLQQNFQDNQFHGKWYQVGRAGNAAPPMDPELLLLTAQTYELKEDKSYDV 66 Query: 74 KFHIIINEECSEIFLVADKTEKAGEYSV----TYDGSNTF--TILKTDYDNYIMIHLINK 127 + C + + + + GE+++ Y G ++ ++ T+Y+ + M+ Sbjct: 67 TAVRFRKKMCEYLTMTFVPSPQPGEFTLGNIKNYPGLTSYFVRVVSTNYNQHAMVFFKKV 126 Query: 128 KDGETFQLMELYGREPDLSSDIKEKFAQLSEEHGIVRENIIDLTNANRCLEA 179 + + + L GR +L+S++KE F + S+ G+ +I+ ++C++ Sbjct: 127 QQNREYFSISLLGRTKELASELKENFIRFSKSLGLPENHIVFPVPIDQCIDG 178 >5JR8-A nrPDB Length = 178 Score = 206 bits (525), Expect = 4e-54, Method: Composition-based stats. Identities = 32/173 (18%), Positives = 81/173 (46%), Gaps = 8/173 (4%) Query: 14 LVCVHAEEASSMERNFNVEKINGEWYTIMLATDKREKIEEHGSMRVFVEYIHVLEN-SLA 72 L+ + +++NF + G+WY + LA + + E+ +++ + E+ S Sbjct: 7 LIPAPPLSSVPLQQNFQDNQFQGKWYVVGLAGNAILR-EDEDPQKMYATIYELKEDKSYN 65 Query: 73 LKFHIIINEECSEIFLVADKTEKAGEYSV----TYDGSNTF--TILKTDYDNYIMIHLIN 126 + + ++ C + GE+++ +Y G ++ ++ T+Y+ + M+ Sbjct: 66 VTSVLFRDDGCDYWIRTFVPGCQPGEFTLGNIQSYPGLTSYLVRVVSTNYNQFAMVFFKK 125 Query: 127 KKDGETFQLMELYGREPDLSSDIKEKFAQLSEEHGIVRENIIDLTNANRCLEA 179 + + + LYGR +L+S+++E F + S+ G+ NI+ ++C++ Sbjct: 126 VSQNQEYFKITLYGRTKELTSELQENFIRFSKSLGLPENNIVFPVPIDQCIDG 178 >2L9C-A nrPDB Length = 176 Score = 202 bits (514), Expect = 7e-53, Method: Composition-based stats. Identities = 162/162 (100%), Positives = 162/162 (100%) Query: 20 EEASSMERNFNVEKINGEWYTIMLATDKREKIEEHGSMRVFVEYIHVLENSLALKFHIII 79 EEASSMERNFNVEKINGEWYTIMLATDKREKIEEHGSMRVFVEYIHVLENSLALKFHIII Sbjct: 15 EEASSMERNFNVEKINGEWYTIMLATDKREKIEEHGSMRVFVEYIHVLENSLALKFHIII 74 Query: 80 NEECSEIFLVADKTEKAGEYSVTYDGSNTFTILKTDYDNYIMIHLINKKDGETFQLMELY 139 NEECSEIFLVADKTEKAGEYSVTYDGSNTFTILKTDYDNYIMIHLINKKDGETFQLMELY Sbjct: 75 NEECSEIFLVADKTEKAGEYSVTYDGSNTFTILKTDYDNYIMIHLINKKDGETFQLMELY 134 Query: 140 GREPDLSSDIKEKFAQLSEEHGIVRENIIDLTNANRCLEARE 181 GREPDLSSDIKEKFAQLSEEHGIVRENIIDLTNANRCLEARE Sbjct: 135 GREPDLSSDIKEKFAQLSEEHGIVRENIIDLTNANRCLEARE 176 >3KFG-A nrPDB Length = 162 Score = 197 bits (500), Expect = 3e-51, Method: Composition-based stats. Identities = 131/162 (80%), Positives = 148/162 (91%) Query: 20 EEASSMERNFNVEKINGEWYTIMLATDKREKIEEHGSMRVFVEYIHVLENSLALKFHIII 79 EEA+S +N NVEKINGEW++I+LA+DKREKIEEHGSMRVFVE+IHVLENSLA KFH +I Sbjct: 1 EEATSKGQNLNVEKINGEWFSILLASDKREKIEEHGSMRVFVEHIHVLENSLAFKFHTVI 60 Query: 80 NEECSEIFLVADKTEKAGEYSVTYDGSNTFTILKTDYDNYIMIHLINKKDGETFQLMELY 139 + ECSEIFLVADKTEKAGEYSV YDG NTFTILKTDYDNYIM HLIN+KDG+TFQLMELY Sbjct: 61 DGECSEIFLVADKTEKAGEYSVMYDGFNTFTILKTDYDNYIMFHLINEKDGKTFQLMELY 120 Query: 140 GREPDLSSDIKEKFAQLSEEHGIVRENIIDLTNANRCLEARE 181 GR+ DL+SDIKEKF +L EEHGI++ENIIDLT NRCL+ARE Sbjct: 121 GRKADLNSDIKEKFVKLCEEHGIIKENIIDLTKTNRCLKARE 162 >2K23-A nrPDB Length = 178 Score = 192 bits (488), Expect = 7e-50, Method: Composition-based stats. Identities = 33/172 (19%), Positives = 76/172 (44%), Gaps = 8/172 (4%) Query: 14 LVCVHAEEASSMERNFNVEKINGEWYTIMLATDKREKIEEHGSMRVFVEYIHVLE-NSLA 72 L+ + ++ F E+ G W+ + LA + +K E ++ + E NS Sbjct: 7 LIPAPPLISVPLQPGFWTERFQGRWFVVGLAGNAVQK-ERQSRFTMYSTIYELQEDNSYN 65 Query: 73 LKFHIIINEECSEIFLVADKTEKAGEYSV----TYDGSNTF--TILKTDYDNYIMIHLIN 126 + ++ + C + + G++++ +Y ++ + TDYD + M+ Sbjct: 66 VTSILVRGQGCRYWIRTFVPSSRPGQFTLGNIHSYPQIQSYDVQVADTDYDQFAMVFFQK 125 Query: 127 KKDGETFQLMELYGREPDLSSDIKEKFAQLSEEHGIVRENIIDLTNANRCLE 178 + + + + LYGR LS ++KE+F ++ G+ NI+ ++C++ Sbjct: 126 TSENKQYFKVTLYGRTKGLSDELKERFVSFAKSLGLKDNNIVFSVPTDQCID 177 >5X7Y-A nrPDB Length = 177 Score = 191 bits (486), Expect = 1e-49, Method: Composition-based stats. Identities = 85/166 (51%), Positives = 120/166 (72%), Gaps = 1/166 (0%) Query: 17 VHAEEASSMERNFNVEKINGEWYTIMLATDKREKIEEHGSMRVFVEYIHVLENS-LALKF 75 H EE ++ NF++ KI+G+WY+I+LA+D +EKIEE+GSMRVFV+ I VL NS L Sbjct: 2 SHEEENDVVKGNFDISKISGDWYSILLASDIKEKIEENGSMRVFVKDIEVLSNSSLIFTM 61 Query: 76 HIIINEECSEIFLVADKTEKAGEYSVTYDGSNTFTILKTDYDNYIMIHLINKKDGETFQL 135 H +N +C++I L+ +KTEK GEY V +DG N F I++T Y++YI+ HL N + FQL Sbjct: 62 HTKVNGKCTKISLICNKTEKDGEYDVVHDGYNLFRIIETAYEDYIIFHLNNVNQEQEFQL 121 Query: 136 MELYGREPDLSSDIKEKFAQLSEEHGIVRENIIDLTNANRCLEARE 181 MELYGR+PD+S +KEKF + + I +ENI+DLT +RCL+AR+ Sbjct: 122 MELYGRKPDVSPKVKEKFVRYCQGMEIPKENILDLTQVDRCLQARQ 167 >3U9P-C nrPDB Length = 182 Score = 190 bits (484), Expect = 2e-49, Method: Composition-based stats. Identities = 36/174 (20%), Positives = 83/174 (47%), Gaps = 10/174 (5%) Query: 14 LVCVHAEEASSMERNFNVEKINGEWYTIMLATDKREKIEEHGSMRVFVEYIHVLENSLAL 73 L+ + ++ +F ++ G WY + LA + +K E GS ++ + EN+ Sbjct: 9 LIPAPSLLTVPLQPDFRSDQFRGRWYVVGLAGNAVQKKTE-GSFTMYSTIYELQENNSYN 67 Query: 74 KFHIIINEE---CSEIFLVADKTEKAGEYSV----TYDGSNTF--TILKTDYDNYIMIHL 124 I++ ++ C + +AG++++ Y ++ + TDY+ + M+ Sbjct: 68 VTSILVRDQDQGCRYWIRTFVPSSRAGQFTLGNMHRYPQVQSYNVQVATTDYNQFAMVFF 127 Query: 125 INKKDGETFQLMELYGREPDLSSDIKEKFAQLSEEHGIVRENIIDLTNANRCLE 178 + + + + LYGR +LS ++KE+F + ++ G+ +NII ++C++ Sbjct: 128 RKTSENKQYFKITLYGRTKELSPELKERFTRFAKSLGLKDDNIIFSVPTDQCID 181 >1EW3-A nrPDB Length = 159 Score = 175 bits (445), Expect = 7e-45, Method: Composition-based stats. Identities = 79/155 (50%), Positives = 112/155 (72%), Gaps = 1/155 (0%) Query: 27 RNFNVEKINGEWYTIMLATDKREKIEEHGSMRVFVEYIHVLENS-LALKFHIIINEECSE 85 RNF++ KI+GEWY+I LA+D +EKIEE+GSMRVFV+ I L+NS L ++ +N EC+E Sbjct: 4 RNFDISKISGEWYSIFLASDVKEKIEENGSMRVFVDVIRALDNSSLYAEYQTKVNGECTE 63 Query: 86 IFLVADKTEKAGEYSVTYDGSNTFTILKTDYDNYIMIHLINKKDGETFQLMELYGREPDL 145 +V DKTE+ G YS+ YDG N F I + + D +I+++L+N FQL E Y REPD+ Sbjct: 64 FPMVFDKTEEDGVYSLNYDGYNVFRISEFENDEHIILYLVNFDKDRPFQLFEFYAREPDV 123 Query: 146 SSDIKEKFAQLSEEHGIVRENIIDLTNANRCLEAR 180 S +IKE+F ++ ++ GIV+ENIIDLT +RC + R Sbjct: 124 SPEIKEEFVKIVQKRGIVKENIIDLTKIDRCFQLR 158 >1GM6-A nrPDB Length = 175 Score = 174 bits (440), Expect = 2e-44, Method: Composition-based stats. Identities = 77/154 (50%), Positives = 113/154 (73%), Gaps = 2/154 (1%) Query: 28 NFNVEKINGEWYTIMLATDKREKIEEHGSMRVFVEYIHVLENS-LALKFHIIINEECSEI 86 NF+ KI GEWY+I+LA+D +E IEE+GSMRVFVE+I VL+NS LA KF +N EC++ Sbjct: 12 NFDASKIAGEWYSILLASDAKENIEENGSMRVFVEHIRVLDNSSLAFKFQRKVNGECTDF 71 Query: 87 FLVADKTEKAGEYSVTYDGSNTFTILKTDYDNYIMIHLINKKDGETFQLMELYGREPDLS 146 + V DK G Y+V Y G N F +L+ +Y +Y+++HL++ +TFQLME YGR+PD+ Sbjct: 72 YAVCDKVGD-GVYTVAYYGENKFRLLEVNYSDYVILHLVDVNGDKTFQLMEFYGRKPDVE 130 Query: 147 SDIKEKFAQLSEEHGIVRENIIDLTNANRCLEAR 180 +K+KF ++ +++GI++ENIIDLT +RC + R Sbjct: 131 PKLKDKFVEICQQYGIIKENIIDLTKIDRCFQLR 164 >2R73-A nrPDB Length = 166 Score = 169 bits (428), Expect = 6e-43, Method: Composition-based stats. Identities = 53/165 (32%), Positives = 88/165 (53%) Query: 12 LTLVCVHAEEASSMERNFNVEKINGEWYTIMLATDKREKIEEHGSMRVFVEYIHVLENSL 71 L C +EE S E+ E+++ W+T++LA+ R IEE G R F++ I V +L Sbjct: 2 LQPECSRSEEDLSDEKERKWEQLSRHWHTVVLASSDRSLIEEEGPFRNFIQNITVESGNL 61 Query: 72 ALKFHIIINEECSEIFLVADKTEKAGEYSVTYDGSNTFTILKTDYDNYIMIHLINKKDGE 131 F N +C ++L A KTE+A ++ + Y G+N + + Y N DG+ Sbjct: 62 NGFFLTRKNGQCIPLYLTAFKTEEARQFKLNYYGTNDVYYESSKPNEYAKFIFYNYHDGK 121 Query: 132 TFQLMELYGREPDLSSDIKEKFAQLSEEHGIVRENIIDLTNANRC 176 + L+GR P+LS++IK++F + G RENI+D++ + C Sbjct: 122 VNVVANLFGRTPNLSNEIKKRFEEDFMNRGFRRENILDISEVDHC 166 >2E4J-A nrPDB Length = 167 Score = 162 bits (411), Expect = 7e-41, Method: Composition-based stats. Identities = 34/161 (21%), Positives = 72/161 (44%), Gaps = 5/161 (3%) Query: 23 SSMERNFNVEKINGEWYTIMLATDKREKIEEHGSMRVFVEYI-HVLENSLALKFHIIINE 81 +++ NF +K G WY+ LA++ E+ + + + E L L + Sbjct: 6 DTVQPNFQQDKFLGRWYSAGLASNSSWFREKKAVLYMCKTVVAPSTEGGLNLTSTFLRKN 65 Query: 82 ECSEIFLVADKTEKAGEYSVTYD---GSNTFTILKTDYDNYIMIHLINKK-DGETFQLME 137 + +V G Y+ + ++ ++++ +YD Y ++ K G+ F++ Sbjct: 66 QAETKIMVLQPAGAPGHYTYSSPHSGSIHSVSVVEANYDEYALLFSRGTKGPGQDFRMAT 125 Query: 138 LYGREPDLSSDIKEKFAQLSEEHGIVRENIIDLTNANRCLE 178 LY R L ++KEKF S+ G+ E+I+ L ++ ++ Sbjct: 126 LYSRTQTLKDELKEKFTTFSKAQGLTEEDIVFLPQPDKAIQ 166 >3O22-A nrPDB Length = 162 Score = 162 bits (410), Expect = 7e-41, Method: Composition-based stats. Identities = 35/159 (22%), Positives = 73/159 (45%), Gaps = 5/159 (3%) Query: 24 SMERNFNVEKINGEWYTIMLATDKREKIEEHGSMRVFVEYI-HVLENSLALKFHIIINEE 82 S++ NF +K G W++ LA++ E+ ++ + + + L L + + Sbjct: 1 SVQPNFQQDKFLGRWFSAGLASNSSWLREKKAALSMAKSVVAPATDGGLNLTSTFLRKNQ 60 Query: 83 CSEIFLVADKTEKAGEYSVT---YDGSNTFTILKTDYDNYIMIHLINKK-DGETFQLMEL 138 C ++ G YS + + + ++++TDYD Y +++ K GE F++ L Sbjct: 61 CETRTMLLQPAGSLGSYSYRSPHWGSTYSVSVVETDYDQYALLYSQGSKGPGEDFRMATL 120 Query: 139 YGREPDLSSDIKEKFAQLSEEHGIVRENIIDLTNANRCL 177 Y R +++KEKF + G + I+ L ++C+ Sbjct: 121 YSRTQTPRAELKEKFTAFCKAQGFTEDTIVFLPQTDKCM 159 >3L4R-A nrPDB Length = 170 Score = 157 bits (397), Expect = 2e-39, Method: Composition-based stats. Identities = 39/162 (24%), Positives = 87/162 (53%) Query: 20 EEASSMERNFNVEKINGEWYTIMLATDKREKIEEHGSMRVFVEYIHVLENSLALKFHIII 79 E + E +E+++G W+++ LA++K + I+ G RVF+ + + +L I Sbjct: 1 MEGNHEEPQGGLEELSGRWHSVALASNKSDLIKPWGHFRVFIHSMSAKDGNLHGDILIPQ 60 Query: 80 NEECSEIFLVADKTEKAGEYSVTYDGSNTFTILKTDYDNYIMIHLINKKDGETFQLMELY 139 + +C ++ L A KT + ++ + Y G N + + D +Y+++++IN+ + +T + L Sbjct: 61 DGQCEKVSLTAFKTATSNKFDLEYWGHNDLYLAEVDPKSYLILYMINQYNDDTSLVAHLM 120 Query: 140 GREPDLSSDIKEKFAQLSEEHGIVRENIIDLTNANRCLEARE 181 R+ D F + E+ G+ ++ I+ L++ +RC +R+ Sbjct: 121 VRDLSRQQDFLPAFESVCEDIGLHKDQIVVLSDDDRCQGSRD 162 >1JZU-A nrPDB Length = 157 Score = 149 bits (376), Expect = 8e-37, Method: Composition-based stats. Identities = 39/148 (26%), Positives = 66/148 (44%), Gaps = 1/148 (0%) Query: 30 NVEKINGEWYTIMLATDKREKIEEHGSMRVFVEYIHVL-ENSLALKFHIIINEECSEIFL 88 + +I G+WY + LA++ + E M++ + I L E+ L + + + C + Sbjct: 5 DRSEIAGKWYVVALASNTEFFLREKDKMKMAMARISFLGEDELKVSYAVPKPNGCRKWET 64 Query: 89 VADKTEKAGEYSVTYDGSNTFTILKTDYDNYIMIHLINKKDGETFQLMELYGREPDLSSD 148 KT GE + + +L TDY +Y +I+ KDG T +M LY R P++S Sbjct: 65 TFKKTSDDGEVYYSEEAKKKVEVLDTDYKSYAVIYATRVKDGRTLHMMRLYSRSPEVSPA 124 Query: 149 IKEKFAQLSEEHGIVRENIIDLTNANRC 176 F +L+ E E + L C Sbjct: 125 ATAIFRKLAGERNYTDEMVAMLPRQEEC 152 >3SAO-A nrPDB Length = 160 Score = 147 bits (371), Expect = 2e-36, Method: Composition-based stats. Identities = 39/148 (26%), Positives = 67/148 (45%), Gaps = 1/148 (0%) Query: 30 NVEKINGEWYTIMLATDKREKIEEHGSMRVFVEYIHVL-ENSLALKFHIIINEECSEIFL 88 + ++ G+WY + LA++ + E G M++ + I L E+ L + + + C + Sbjct: 4 DRSEVAGKWYIVALASNTDFFLAEKGKMKMVMARISFLGEDELEVSYAAPSPKGCRKWET 63 Query: 89 VADKTEKAGEYSVTYDGSNTFTILKTDYDNYIMIHLINKKDGETFQLMELYGREPDLSSD 148 KT GE + + T +L TDY +Y +I KDG T +M LY R ++S Sbjct: 64 TFKKTSDDGEVYYSEEAEKTVEVLDTDYKSYAVIFATRVKDGRTLHMMRLYSRSREVSPT 123 Query: 149 IKEKFAQLSEEHGIVRENIIDLTNANRC 176 F +L+ E E + L + C Sbjct: 124 AMAIFRKLARERNYTDEMVAVLPSQAAC 151 >1E5P-A nrPDB Length = 151 Score = 137 bits (346), Expect = 2e-33, Method: Composition-based stats. Identities = 40/152 (26%), Positives = 76/152 (50%), Gaps = 3/152 (1%) Query: 29 FNVEKINGEWYTIMLATDKREKIEEHGSMRVFVEYIHVLENS--LALKFHIIINEECSEI 86 + ++ G+WYTI++A D EKIEE G +R + +I +N + + F++I N +CS+ Sbjct: 1 QDFAELQGKWYTIVIAADNLEKIEEGGPLRFYFRHIDCYKNCSEMEITFYVITNNQCSKT 60 Query: 87 FLVADKTEKAGEYSVTYDGSNTFTILKTDYDNYIMIHLINKKDGETFQLMELYGREPDLS 146 ++ + G Y ++G+N F L D + + G+ ++ + G+ L+ Sbjct: 61 TVIG-YLKGNGTYETQFEGNNIFQPLYITSDKIFFTNKNMDRAGQETNMIVVAGKGNALT 119 Query: 147 SDIKEKFAQLSEEHGIVRENIIDLTNANRCLE 178 + E Q + E I ENI+++ + C E Sbjct: 120 PEENEILVQFAHEKKIPVENILNILATDTCPE 151 >1EPB-A nrPDB Length = 164 Score = 136 bits (342), Expect = 6e-33, Method: Composition-based stats. Identities = 34/153 (22%), Positives = 66/153 (43%), Gaps = 1/153 (0%) Query: 27 RNFNVEKINGEWYTIMLATDKREKIEEHGSMRVFVEYIHVLENSLALKFHIIINEECSEI 86 ++F++ K G WY I A+ H ++ + + EN LAL + C Sbjct: 4 KDFDISKFLGFWYEIAFASKMGTPGLAHKEEKMGAMVVELKENLLALTTTYYSEDHCVLE 63 Query: 87 FLVADKTEKAGEYSVTY-DGSNTFTILKTDYDNYIMIHLINKKDGETFQLMELYGREPDL 145 + A + + ++ VT G + TDY Y +I + + G + M+LY R D Sbjct: 64 KVTATEGDGPAKFQVTRLSGKKEVVVEATDYLTYAIIDITSLVAGAVHRTMKLYSRSLDD 123 Query: 146 SSDIKEKFAQLSEEHGIVRENIIDLTNANRCLE 178 + + F +++ +HG ++ L + C++ Sbjct: 124 NGEALYNFRKITSDHGFSETDLYILKHDLTCVK 156 >1E06-A nrPDB Length = 157 Score = 134 bits (338), Expect = 2e-32, Method: Composition-based stats. Identities = 40/154 (25%), Positives = 73/154 (47%), Gaps = 3/154 (1%) Query: 26 ERNFNVEKINGEWYTIMLATDKREKIEEHGSMRVFVEYIHV--LENSLALKFHIIINEEC 83 + + +++G+W T + + EKI E+ +VF+ I E+ + L F N C Sbjct: 4 QPEQDPFELSGKWITSYIGSSDLEKIGENAPFQVFMRSIEFDDKESKVYLNFFSKENGIC 63 Query: 84 SEIFLVADKTEKAGEYSVTYDGSNTFTILKTDYDNYIMIHLINKKDGETFQLMELYGREP 143 E L+ K E Y V Y G+N F + I+ ++ ++G+ + L G+ Sbjct: 64 EEFSLIGTKQE-GNTYDVNYAGNNKFVVSYASETALIISNINVDEEGDKTIMTGLLGKGT 122 Query: 144 DLSSDIKEKFAQLSEEHGIVRENIIDLTNANRCL 177 D+ EKF +++ E+GI ENI+++ + C Sbjct: 123 DIEDQDLEKFKEVTRENGIPEENIVNIIERDDCP 156 >4RUN-A nrPDB Length = 161 Score = 125 bits (314), Expect = 9e-30, Method: Composition-based stats. Identities = 32/150 (21%), Positives = 62/150 (41%), Gaps = 3/150 (2%) Query: 29 FNVEKINGEWYTIMLATDKREKIEEHGSMRVFVEYIHVLENSLALKFHIIINEECSEIFL 88 E I G WY + DK + V+ + +L F + + C + + Sbjct: 5 LEEEDITGTWYVKAMVVDKDFPEDRRPRKVSPVKVTALGGGNLEATFTFMREDRCIQKKI 64 Query: 89 VADKTEKAGEYSVTYDGSNTFTILK-TDYDNYIMIHLINKKDGETFQLMELYGREPDLSS 147 + KTE+ G++S Y G + + D+Y+ ++ G + + L GR P+ + Sbjct: 65 LMRKTEEPGKFSA-YGGRKLIYLQELPGTDDYVFYSKDQRRGGLRY-MGNLVGRNPNTNL 122 Query: 148 DIKEKFAQLSEEHGIVRENIIDLTNANRCL 177 + E+F +L + G+ E+I C+ Sbjct: 123 EALEEFKKLVQHKGLSEEDIFMPLQTGSCV 152 >3EYC-A nrPDB Length = 162 Score = 122 bits (307), Expect = 7e-29, Method: Composition-based stats. Identities = 31/148 (20%), Positives = 70/148 (47%), Gaps = 4/148 (2%) Query: 30 NVEKINGEWYTIMLATDKREKIEEHGSMRVFVEYIHVLEN-SLALKFHIIINEECSEIFL 88 ++ ++G WY + D+ E V + LE +L K ++I+ C E+ Sbjct: 5 EIQDVSGTWYLKAMTVDREFP--EMNLESVTPMTLTTLEGGNLEAKVTMLISGRCQEVKA 62 Query: 89 VADKTEKAGEYSVTYDGSNTFTILKTDYDNYIMIHLINKKDGETFQLMELYGREPDLSSD 148 V +KT++ G+Y+ G + I+++ ++ + + + G+ + ++L GR+P + + Sbjct: 63 VLEKTDEPGKYTAD-GGKHVAYIIRSHVKDHYIFYSEGELHGKPVRGVKLVGRDPKNNLE 121 Query: 149 IKEKFAQLSEEHGIVRENIIDLTNANRC 176 E F + + G+ E+I+ + C Sbjct: 122 ALEDFEKAAGARGLSTESILIPRQSETC 149 >4WFU-A nrPDB Length = 156 Score = 122 bits (307), Expect = 7e-29, Method: Composition-based stats. Identities = 40/154 (25%), Positives = 74/154 (48%), Gaps = 6/154 (3%) Query: 27 RNFNVEKINGEWYTIMLATDKREKIEEHGSMRVFVEYIHVLEN--SLALKFHIIINEECS 84 + KI GEW I A D ++KI E G +R + I + + SL++ F++ C Sbjct: 5 AEIDPSKIPGEWRIIYAAADNKDKIVEGGPLRNYYRRIECINDCESLSITFYLKDQGTCL 64 Query: 85 EIFLVADKTEKAGEYSVTYDGSNTFTILKTDYDNYIMIHLINKKDGET-FQLMELYGREP 143 + VA K ++ Y + + G+NT ++ + +++ + DGE ++ E + Sbjct: 65 LLTEVA-KRQEGYVYVLEFYGTNTLEVIHVSEN--MLVTYVENYDGERITKMTEGLAKGT 121 Query: 144 DLSSDIKEKFAQLSEEHGIVRENIIDLTNANRCL 177 + + EK+ QL+ E G+ ENI +L + C Sbjct: 122 SFTPEELEKYQQLNSERGVPNENIENLIKTDNCP 155 >1G85-A nrPDB Length = 159 Score = 118 bits (297), Expect = 9e-28, Method: Composition-based stats. Identities = 35/156 (22%), Positives = 75/156 (48%), Gaps = 4/156 (2%) Query: 22 ASSMERNFNVEKINGEWYTIMLATDKREKIEEHGSMRVFVEYIHVLENSLALKFHI--II 79 A E N+ +++G W T+ + + EKI+E+G R + + + + F+ Sbjct: 1 AQEEEAEQNLSELSGPWRTVYIGSTNPEKIQENGPFRTYFRELVFDDEKGTVDFYFSVKR 60 Query: 80 NEECSEIFLVADKTEKAGEYSVTYDGSNTFTILKTDYDNYIMIHLINKKDGETFQLMELY 139 + + + + A K + G Y Y+G N F I+ + + ++ K G+T +L L+ Sbjct: 61 DGKWKNVHVKATKQDD-GTYVADYEGQNVFKIVSLSRTHLVAHNINVDKHGQTTELTGLF 119 Query: 140 GREPDLSSDIKEKFAQLSEEHGIVRENIIDLTNANR 175 + ++ + EKF +L+E+ GI ++N+++ Sbjct: 120 VK-LNVEDEDLEKFWKLTEDKGIDKKNVVNFLENEN 154 >1EXS-A nrPDB Length = 160 Score = 117 bits (293), Expect = 3e-27, Method: Composition-based stats. Identities = 29/145 (20%), Positives = 66/145 (45%), Gaps = 2/145 (1%) Query: 21 EASSMERNFNVEKINGEWYTIMLATDKREKIEEHG-SMRVFVEYI-HVLENSLALKFHII 78 E + + + +K+ G W+T+ +A ++ ++ +VE + E L + Sbjct: 2 EVTPIMTELDTQKVAGTWHTVAMAVSDVSLLDAKSSPLKAYVEGLKPTPEGDLEILLQKR 61 Query: 79 INEECSEIFLVADKTEKAGEYSVTYDGSNTFTILKTDYDNYIMIHLINKKDGETFQLMEL 138 N++C++ L+A KT+ + + N +L TDYD+++++ + N E + + Sbjct: 62 ENDKCAQEVLLAKKTDIPAVFKINALDENQLFLLDTDYDSHLLLCMENSASPEHSLVCQS 121 Query: 139 YGREPDLSSDIKEKFAQLSEEHGIV 163 R ++ I+EKF + + Sbjct: 122 LARTLEVDDQIREKFEDALKTLSVP 146 >4R0B-A nrPDB Length = 169 Score = 105 bits (261), Expect = 2e-23, Method: Composition-based stats. Identities = 29/135 (21%), Positives = 64/135 (47%), Gaps = 2/135 (1%) Query: 26 ERNFNVEKINGEWYTIMLATDKREKIEE-HGSMRVFVEYI-HVLENSLALKFHIIINEEC 83 +++ + K+ G W+++ +AT++ + +RV + + E++L + H N C Sbjct: 6 KQDLELPKLAGTWHSMAMATNEISLMATLKAPLRVHITSLLPTPEDNLEIVLHRWENNSC 65 Query: 84 SEIFLVADKTEKAGEYSVTYDGSNTFTILKTDYDNYIMIHLINKKDGETFQLMELYGREP 143 E ++ +KTE ++ + Y +N T+L TDYDN++ + L + + + R Sbjct: 66 VEKKVLGEKTENPKKFKINYTVANEATLLDTDYDNFLFLCLQDTTTPIQSMMCQYLARVL 125 Query: 144 DLSSDIKEKFAQLSE 158 +I + F + Sbjct: 126 VEDDEIMQGFIRAFR 140 >4QAF-A nrPDB Length = 152 Score = 90.8 bits (224), Expect = 3e-19, Method: Composition-based stats. Identities = 30/147 (20%), Positives = 59/147 (40%), Gaps = 4/147 (2%) Query: 30 NVEKINGEWYTIMLATDKREKIEEHGSMRVFVEYIHVLEN-SLALKFHIIINEECSEIFL 88 ++ ++G WY + D GS V + LE +L K + I E+ Sbjct: 5 EIQDVSGTWYLKAMTVDVGALRCLAGS--VIPTTLTTLEGGNLEAKVTMHIKGRSQEVKA 62 Query: 89 VADKTEKAGEYSVTYDGSNTFTILKTDYDNYIMIHLINKKDGETFQLMELYGREPDLSSD 148 V KT++ G Y+ G + I ++ ++ + + G + L GR+P + + Sbjct: 63 VLSKTDEPGIYTA-IGGIHVAKIGRSHVKDHYIFYSEGCLSGVPVPGVWLVGRDPKNNLE 121 Query: 149 IKEKFAQLSEEHGIVRENIIDLTNANR 175 E F + + G+ E+I+ + Sbjct: 122 ALEDFEKAAGARGLSTESILIPRQSET 148 >2RD7-C nrPDB Length = 184 Score = 74.3 bits (181), Expect = 3e-14, Method: Composition-based stats. Identities = 24/164 (14%), Positives = 59/164 (35%), Gaps = 7/164 (4%) Query: 16 CVHAEEASSMERNFNVEKINGEWYTIMLATDKREKIEEHGSMRVFVEYIHVLENSLALKF 75 + NF+ ++ G W + + + R E+ ++ ++A+ Sbjct: 11 PASPISTIQPKANFDAQQFAGTWLLVAVGSACRFLQEQGHRAEATTLHVAPQGTAMAVST 70 Query: 76 HIIINEECSEIFLVADKTEKAGEYSV---TYDGSNTFTILKTDYDNYIMIHLINKKDGET 132 ++ C ++ + T G + + G+ + +TDY ++ +++L Sbjct: 71 FRKLDGICWQVRQLYGDTGVLGRFLLQARDARGAVHVVVAETDYQSFAVLYLERAGQ--- 127 Query: 133 FQLMELYGREPDLSSDIKEKFAQLSEEHGIVRENIIDLTNANRC 176 ++LY R +S + F Q +E + + I C Sbjct: 128 -LSVKLYARSLPVSDSVLSGFEQRVQEAHLTEDQIFYFPKYGFC 170 >1IIU-A nrPDB Length = 174 Score = 54.6 bits (130), Expect = 2e-08, Method: Composition-based stats. Identities = 27/170 (15%), Positives = 62/170 (36%), Gaps = 34/170 (20%) Query: 25 MERNFNVEKINGEWYTIMLATDKREKIEEHGSMRVFVEYIHVLENSLALKFHIIIN---- 80 ++ NF+ + +G WY + + ++++ V ++ ++ + Sbjct: 10 VKENFDKNRYSGTWYAMAKKDPEGLFLQDN----VVAQFTVDENGQMSATAKGRVRLFNN 65 Query: 81 -EECSEIFLVADKTEKAGEYSVTYDGSNTF--------TILKTDYDNYIMIHLINKKDGE 131 + C+++ TE ++ + Y G +F ++ TDYD Y + H ++ E Sbjct: 66 WDVCADMIGSFTDTEDPAKFKMKYWGVASFLQKGNDDHWVVDTDYDTYAL-HYSCRELNE 124 Query: 132 TFQLMELYGREPDLSSDIKEKFAQLSEE-HGIVRE--NIIDLTNANRCLE 178 + Y F S + G+ E I+ + CL+ Sbjct: 125 DGTCADSYS------------FV-FSRDPKGLPPEAQKIVRQRQIDLCLD 161 >4PSQ-B nrPDB Length = 212 Score = 51.2 bits (121), Expect = 3e-07, Method: Composition-based stats. Identities = 19/108 (17%), Positives = 47/108 (43%), Gaps = 9/108 (8%) Query: 25 MERNFNVEKINGEWYTIMLATDKREKIEEHGSMRVFVEYIHVLENSLALKFHIIIN-EEC 83 ++ NF+ + +G WY + + ++++ V+ + + + ++ N + C Sbjct: 40 VKENFDKARFSGTWYAMAKKDPEGLFLQDNIVAEFSVDETGQMSATAKGRVRLLNNWDVC 99 Query: 84 SEIFLVADKTEKAGEYSVTYDGSNTF--------TILKTDYDNYIMIH 123 +++ TE ++ + Y G +F I+ TDYD Y + + Sbjct: 100 ADMVGTFTDTEDPAKFKMKYWGVASFLQKGNDDHWIVDTDYDTYAVQY 147 >1JYJ-A nrPDB Length = 183 Score = 49.2 bits (116), Expect = 8e-07, Method: Composition-based stats. Identities = 19/108 (17%), Positives = 47/108 (43%), Gaps = 9/108 (8%) Query: 25 MERNFNVEKINGEWYTIMLATDKREKIEEHGSMRVFVEYIHVLENSLALKFHIIIN-EEC 83 ++ NF+ + +G WY + + ++++ V+ + + + ++ N + C Sbjct: 12 VKENFDKARFSGTWYAMAKKDPEGLFLQDNIVAEFSVDETGQMSATAKGRVRLLNNLDVC 71 Query: 84 SEIFLVADKTEKAGEYSVTYDGSNTF--------TILKTDYDNYIMIH 123 +++ TE ++ + Y G +F I+ TDYD Y + + Sbjct: 72 ADMVGTFTDTEDPAKFKMKYHGVASFLQKGNDDHWIVDTDYDTYAVQY 119 >1BBP-A nrPDB Length = 173 Score = 48.5 bits (114), Expect = 2e-06, Method: Composition-based stats. Identities = 26/132 (19%), Positives = 52/132 (39%), Gaps = 14/132 (10%) Query: 28 NFNVEKINGEWYTIMLATDKREKIEEHGSMRVFVEYIHVLENSLALKFHIIINEECSEIF 87 NF+ +G+W+ + + EK + G S+ + + +I+ + I Sbjct: 16 NFDWSNYHGKWWEVAKYPNSVEKYGKCG-----WAEYTPEGKSVKVSNYHVIHGKEYFIE 70 Query: 88 LVADKTEKA--GE--YSVTYDG---SNTFTILKTDYDNYIMIHLINKKDGETFQ--LMEL 138 A + G+ + +TY G N F +L TD NYI+ + + + + + Sbjct: 71 GTAYPVGDSKIGKIYHKLTYGGVTKENVFNVLSTDNKNYIIGYYCKYDEDKKGHQDFVWV 130 Query: 139 YGREPDLSSDIK 150 R L+ + K Sbjct: 131 LSRSKVLTGEAK 142 >1GKA-B nrPDB Length = 174 Score = 47.7 bits (112), Expect = 3e-06, Method: Composition-based stats. Identities = 23/163 (14%), Positives = 61/163 (37%), Gaps = 20/163 (12%) Query: 26 ERNFNVEKINGEWYTIMLATDKREKIEE-----------HGSMRVFVEYIHVLENSLALK 74 + NF++ + G WY + + + + +V + + L + Sbjct: 18 QDNFDLRRYAGRWYQTHIIENAYQPVTRCIHSNYEYSTNDYGFKVTTAGFNPNDEYLKID 77 Query: 75 FHIIINEECSEIFLVADKTEKAGEYSVTYDGSNTFTILKTDYDNYIMIHLINKKDGETFQ 134 F + +E ++ + ++ Y+ +++TDY+ Y ++ D + Sbjct: 78 FKVYPTKEFPAAHMLI---DAPSVFAAPYE------VIETDYETYSCVYSCITTDNYKSE 128 Query: 135 LMELYGREPDLSSDIKEKFAQLSEEHGIVRENIIDLTNANRCL 177 ++ R P S EK A + ++G+ + +++ C+ Sbjct: 129 FAFVFSRTPQTSGPAVEKTAAVFNKNGVEFSKFVPVSHTAECV 171 >1FEM-A nrPDB Length = 183 Score = 46.9 bits (110), Expect = 5e-06, Method: Composition-based stats. Identities = 22/119 (18%), Positives = 45/119 (37%), Gaps = 31/119 (26%) Query: 25 MERNFNVEKINGEWYTIMLATDKRE------------KIEEHGSMRVFVEYIHVLENSLA 72 ++ NF+ + G WY +A E ++E+G M + L N+ Sbjct: 11 VKENFDKARFAGTWY--AMAKKDPEGLFLQDNIVAEFSVDENGHMSATAKGRVRLLNNWD 68 Query: 73 LKFHIIINEECSEIFLVADKTEKAGEYSVTYDGSNTF--------TILKTDYDNYIMIH 123 + C+++ TE ++ + Y G +F I+ TDY+ + + + Sbjct: 69 V---------CADMVGTFTDTEDPAKFKMKYWGVASFLQKGNDDHWIIDTDYETFAVQY 118 >1KXO-A nrPDB Length = 184 Score = 46.5 bits (109), Expect = 6e-06, Method: Composition-based stats. Identities = 22/132 (16%), Positives = 49/132 (37%), Gaps = 14/132 (10%) Query: 28 NFNVEKINGEWYTIMLATDKREKIEEHGSMRVFVEYIHVLENSLALKFHIIINEECSEIF 87 NF+ + +G+W+ + D K + G S+ + + +I+ + Sbjct: 16 NFDWSQYHGKWWQVAAYPDHITKYGKCG-----WAEYTPEGKSVKVSRYSVIHGKEYFSE 70 Query: 88 LVADKTEKA--GEYSVTY-----DGSNTFTILKTDYDNYIMIHLINKKDGETFQL--MEL 138 A + G+ +Y F +L TD NYI+ + + + + + + + Sbjct: 71 GTAYPVGDSKIGKIYHSYTIGGVTQEGVFNVLSTDNKNYIIGYFCSYDEDKKGHMDLVWV 130 Query: 139 YGREPDLSSDIK 150 R L+ + K Sbjct: 131 LSRSMVLTGEAK 142 >3MBT-A nrPDB Length = 168 Score = 45.4 bits (106), Expect = 2e-05, Method: Composition-based stats. Identities = 21/154 (13%), Positives = 50/154 (32%), Gaps = 18/154 (11%) Query: 16 CVHAEEASSMERNFNVEKINGEWYTIMLATDKREKIEEHGSMRVFVEYIHVLENSLAL-- 73 ++ NF+ ++ G WY I + E G +V Y + L + Sbjct: 4 PTPP-RGVTVVNNFDAKRYLGTWYEIAR----FDHRFERGLEKVTATYSLRDDGGLNVIN 58 Query: 74 KFHIIINEECS----EIFLVADKTEKAGEYSVTYDGSNTFTILKTDYD-NYIMIHLINKK 128 K + + + T A + S + ++ D + + ++ Sbjct: 59 KGYNPDRGMWQQSEGKAYFTGAPTRAALKVSFFGPFYGGYNVIALDREYRHALV----SG 114 Query: 129 DGETFQLMELYGREPDLSSDIKEKFAQLSEEHGI 162 + + R P +S ++K++ ++ G Sbjct: 115 PDRDYLWI--LSRTPTISDEVKQEMLAVATREGF 146 >2ACO-A nrPDB Length = 173 Score = 44.6 bits (104), Expect = 2e-05, Method: Composition-based stats. Identities = 21/153 (13%), Positives = 50/153 (32%), Gaps = 17/153 (11%) Query: 17 VHAEEASSMERNFNVEKINGEWYTIMLATDKREKIEEHGSMRVFVEYIHVLENSLAL--K 74 ++ NF+ ++ G WY I + E G +V Y + L + K Sbjct: 18 STPPRGVTVVNNFDAKRYLGTWYEIAR----FDHRFERGLEKVTATYSLRDDGGLNVINK 73 Query: 75 FHIIINEECS----EIFLVADKTEKAGEYSVTYDGSNTFTILKTDYD-NYIMIHLINKKD 129 + + + T A + S + ++ D + + ++ Sbjct: 74 GYNPDRGMWQQSEGKAYFTGAPTRAALKVSFFGPFYGGYNVIALDREYRHALVC----GP 129 Query: 130 GETFQLMELYGREPDLSSDIKEKFAQLSEEHGI 162 + + R P +S ++K++ ++ G Sbjct: 130 DRDYLWI--LSRTPTISDEVKQEMLAVATREGF 160 >1N0S-A nrPDB Length = 184 Score = 41.5 bits (96), Expect = 2e-04, Method: Composition-based stats. Identities = 19/132 (14%), Positives = 46/132 (34%), Gaps = 14/132 (10%) Query: 28 NFNVEKINGEWYTIMLATDKREKIEEHGSMRVFVEYIHVLENSLALKFHIIINEECSEIF 87 NF+ + +G+W+ + + + S+ + + +I+ + + Sbjct: 16 NFDWSQYHGKWWEVA-----KYPSPNGKYGKCGWAEYTPEGKSVKVSRYDVIHGKEYFME 70 Query: 88 LVADKTEKA--GEYSVT-----YDGSNTFTILKTDYDNYIMIHLINKKDGETFQL--MEL 138 A + G+ + Y F +L TD NYI+ + + + + + Sbjct: 71 GTAYPVGDSKIGKIYHSRTVGGYTRKTVFNVLSTDNKNYIIGYSCRYDEDKKGHWDHVWV 130 Query: 139 YGREPDLSSDIK 150 R L+ + K Sbjct: 131 LSRSMVLTGEAK 142 >3KQ0-A nrPDB Length = 192 Score = 41.5 bits (96), Expect = 2e-04, Method: Composition-based stats. Identities = 24/176 (13%), Positives = 61/176 (34%), Gaps = 21/176 (11%) Query: 8 LCLGLTLVCVHAEEASSMERNFNVEKINGEWYTIMLATDKREKIEEHGSMRVFVEYIHVL 67 LC L V + N +++I G+W+ +A+ R + + + + Sbjct: 4 LCANLVPVPI---------TNATLDQITGKWF--YIASAFRNEEYNKSVQEIQATFFYFT 52 Query: 68 ENSLALKFHII----INEECSEIFLVADKTEKAGEYSVTYDGSNTFT--ILKTDYDNYIM 121 N + ++C + + G S G F ++ D Y++ Sbjct: 53 PNKTEDTIFLREYQTRQDQCIYNTTYLNVQRENGTISRYVGGQEHFAHLLILRDTKTYML 112 Query: 122 IHLINKKDGETFQLMELYGREPDLSSDIKEKFAQLSEEHGIVRENIIDLT-NANRC 176 + E + +Y +P+ + + +F + + I + +++ ++C Sbjct: 113 AF---DVNDEKNWGLSVYADKPETTKEQLGEFYEALDCLRIPKSDVVYTDWKKDKC 165 >2HZQ-A nrPDB Length = 174 Score = 38.4 bits (88), Expect = 0.002, Method: Composition-based stats. Identities = 27/154 (17%), Positives = 56/154 (36%), Gaps = 23/154 (14%) Query: 24 SMERNFNVEKINGEWYTI---------MLATDKREKIEEHGSMRVFVEYIHVLENSLALK 74 ++ NF+V K G WY I + E+G ++V + + + ++ Sbjct: 10 PVQENFDVNKYPGRWYEIEKIPTTFENGRCIQANYSLMENGKIKVLNQELRA-DGTVN-- 66 Query: 75 FHIIINEECSEIFLVADKTEKAGEYSVTYDGSNTFTILKTDYDNYIMIHL-INKKDGETF 133 I E + + L + + ++S S + IL TDY+NY +++ + Sbjct: 67 ---QIEGEATPVNLT-EPAKLEVKFSWFMP-SAPYHILATDYENYALVYSCTSISQSFHV 121 Query: 134 QLMELYGREPDLSSDIKEKFAQLSEEHGIVRENI 167 + R L + + + + NI Sbjct: 122 DFAWILARNVALPPETVDSLKNI-----LTSNNI 150 >1Z24-A nrPDB Length = 189 Score = 38.1 bits (87), Expect = 0.002, Method: Composition-based stats. Identities = 21/136 (15%), Positives = 46/136 (33%), Gaps = 17/136 (12%) Query: 28 NFNVEKINGEWYTIMLATDKREKIEEHGSMRVFVEYIHVLENSLALKFHIIINEECSEIF 87 +F++ G W+ I + +E + + ++ + N + Sbjct: 17 DFDLSAFAGAWHEIA-----KLPLENENQGKCTIAEYKYDGKKASVYNSFVSNGVKEYME 71 Query: 88 LVAD-----KTEKAGEYSVTYD-GSNTFT----ILKTDYDNYIMIHLINKKDGETFQLME 137 + K K G+Y +T+ G +L TDY NY + + + + + Sbjct: 72 GDLEIAPDAKYTKQGKYVMTFKFGQRVVNLVPWVLATDYKNYAINYNCDYHPDKKAHSIH 131 Query: 138 --LYGREPDLSSDIKE 151 + + L + KE Sbjct: 132 AWILSKSKVLEGNTKE 147 >3EBK-A nrPDB Length = 176 Score = 34.6 bits (78), Expect = 0.025, Method: Composition-based stats. Identities = 15/104 (14%), Positives = 40/104 (38%), Gaps = 14/104 (13%) Query: 24 SMERNFNVEKINGEWYTIMLATDKREKIEEHGSMRVFVEYIHVLENSLALKFHIIINEEC 83 S+ N + E+ G W ++ + + + +++L + + + Sbjct: 15 SLVPNLDYERFRGSWIIAAGTSEALTQYKCWIDRFSY-------DDAL-VSKYTDSQGKN 66 Query: 84 SEIFLVADKTEKAGEYSVTYDGSNT-----FTILKTDYDNYIMI 122 K E ++++ Y+ +++L TDY+NY ++ Sbjct: 67 RTTIRGRTKFE-GNKFTIDYNDKGKAFSAPYSVLATDYENYAIV 109 >3APW-A nrPDB Length = 190 Score = 34.2 bits (77), Expect = 0.035, Method: Composition-based stats. Identities = 28/176 (15%), Positives = 61/176 (34%), Gaps = 21/176 (11%) Query: 8 LCLGLTLVCVHAEEASSMERNFNVEKINGEWYTIMLATDKRE--KIEEHGSMRVFVEYIH 65 LC L V + N +++I G+W+ I A E K + F + Sbjct: 5 LCANLVPVPI---------TNATLDRITGKWFYIASAFRNEEYNKSVQEIQATFFYFTPN 55 Query: 66 VLENSLALKFHIIINEECSEIFLVADKTEKAGEYSVTYDGS----NTFTILKTDYDNYIM 121 E+++ L+ + +C + + G S G + + T Sbjct: 56 KTEDTIFLREYQTRQNQCFYNSSYLNVQRENGTVSRYEGGREHVAHLLFLRDTKT----- 110 Query: 122 IHLINKKDGETFQLMELYGREPDLSSDIKEKFAQLSEEHGIVRENIIDLT-NANRC 176 + + D E + Y +P+ + + +F + + I R +++ ++C Sbjct: 111 LMFGSYLDDEKNWGLSFYADKPETTKEQLGEFYEALDCLRIPRSDVMYTDWKKDKC 166 >1OBQ-A nrPDB Length = 181 Score = 33.8 bits (76), Expect = 0.038, Method: Composition-based stats. Identities = 29/165 (17%), Positives = 55/165 (33%), Gaps = 26/165 (15%) Query: 26 ERNFNVEKINGEWYTIMLATDKREKIEE--------HGSMRVFVEYIHVLENSLALKFHI 77 E+ N G WY L + + IE+ G V + +L + Sbjct: 23 EQTPNRNSYAGVWYQFALTNNPYQLIEKCVRNEYSFDGKQFVIESTGIAYDGNL-----L 77 Query: 78 IINEECSEIFLVADKTEKAGEYSVTYDGSNTF----TILKTDYDNYIMIHLINKKD-GET 132 N + L + + S+ Y+ N+F IL+TDY NY ++ + G Sbjct: 78 KRNGK-----LYPNPFGEP-HLSIDYE--NSFAAPLVILETDYSNYACLYSCIDYNFGYH 129 Query: 133 FQLMELYGREPDLSSDIKEKFAQLSEEHGIVRENIIDLTNANRCL 177 ++ R +L+ +K + + + + C Sbjct: 130 SDFSFIFSRSANLADQYVKKCEAAFKNINVDTTRFVKTVQGSSCP 174 >3CQR-A nrPDB Length = 185 Score = 32.7 bits (73), Expect = 0.091, Method: Composition-based stats. Identities = 27/175 (15%), Positives = 61/175 (34%), Gaps = 22/175 (12%) Query: 16 CVHAEEASSMERNFNVEKINGEWYTIMLATDKREKIEEHGSMRVFVEYIHVLENSLALKF 75 + +NFN+ NG+WY I + + E + L +++ + Sbjct: 7 PAPDPSV--LVQNFNISDFNGKWY-ITSGLNPTFDAFDCQLHEFHTEGDNKLVGNISWRI 63 Query: 76 HIIINEECSEIFLVADK--TEKAGEYSVTYDGSNTF-------TILKT----DYDNYIMI 122 + + A + + + V Y+ N + IL + ++YI + Sbjct: 64 KTLDSG---FFTRSAVQKFVQDPNQPGVLYNHDNEYLHYQDDWYILSSKIENKPEDYIFV 120 Query: 123 HLINKKDG-ETFQLMELYGREPDLSSDIKEKFAQLSEEHGIVRENIIDLTNANRC 176 + + D + + +Y R L + I + + ++ G R+ + N C Sbjct: 121 YYRGRNDAWDGYGGAVVYTRSSVLPNSIIPELEKAAKSIG--RDFSTFIRTDNTC 173 >1YRZ-A nrPDB Length = 528 Score = 31.5 bits (70), Expect = 0.20, Method: Composition-based stats. Identities = 18/126 (14%), Positives = 48/126 (38%), Gaps = 11/126 (8%) Query: 15 VCVHAEEASSMERNFNVEKINGEWYTIMLATDKRE--KIEEHGSMRVFVEYIHVLENSLA 72 + H E +F+ +++ +W T+ + D E G +R+ +S + Sbjct: 313 LPEHPFEKEPELDDFDAPQLHHQWNTLRIPADPSWCSLEERPGHLRLRGMESLTSVHSQS 372 Query: 73 LKFHIIINEECSEIFLVADKTEKAGEYSVTYDGSNTFTILKTDYDNYIMIHLI-NKKDGE 131 L + C + EY ++ D ++++ +H+ +++ G+ Sbjct: 373 LVARRQQSFHCEVETKL--------EYQPESFQHMAGLVIYYDTEDHVYLHVTWHEEKGK 424 Query: 132 TFQLME 137 Q+++ Sbjct: 425 CLQIIQ 430 >2WM5-A nrPDB Length = 435 Score = 29.6 bits (65), Expect = 0.70, Method: Composition-based stats. Identities = 13/87 (14%), Positives = 27/87 (31%), Gaps = 11/87 (12%) Query: 19 AEEASSMERNFNVEKINGEWYTIMLATDKREKIEEHGSMRVFVEYIHVLENSLALKFHII 78 A +R+ +G LA E+I S V++ + L + Sbjct: 289 ALSRYPEQRDRWWSDFDG------LAPTAVEEIVRWASPVVYMRRTLTQDIELRGT-KMA 341 Query: 79 INEECSEIFLVAD----KTEKAGEYSV 101 ++ S + A+ K + + Sbjct: 342 AGDKVSLWYCSANRDESKFADPWTFDL 368 >1AJ8-A nrPDB Length = 371 Score = 28.8 bits (63), Expect = 1.4, Method: Composition-based stats. Identities = 10/29 (34%), Positives = 16/29 (55%), Gaps = 3/29 (10%) Query: 140 GREPDLSSDIKEKFAQ-LSEEHGIVRENI 167 G+ P LS E F + L++ G+ +E I Sbjct: 51 GKLPSLS--ELENFKKELAKSRGLPKEVI 77 >5H9K-A nrPDB Length = 156 Score = 28.0 bits (61), Expect = 2.2, Method: Composition-based stats. Identities = 24/139 (17%), Positives = 50/139 (35%), Gaps = 30/139 (21%) Query: 25 MERNFNVEKI-NGEWYTIMLATDKREKIEEHGSMRVFVEYIHVLENSLALKFHIIINE-E 82 + F+ + G+WY + E + ++L L F+ + + Sbjct: 17 IMSGFDANRFFTGDWYLTHSRDSEVPVRCEK----------YQTGSNLQLNFNGKNGDVK 66 Query: 83 CSEIFLVADKTEKAGEYSVTYDGSNTFT--ILKTDYDNYIMIHLINKKDGETFQLMELYG 140 CS + ++ + + + T GS T +++TDY NY +++ LYG Sbjct: 67 CSGSTVSGNQGFYSFQCTTTSGGSFTSYMAVVETDYANYALLYR-----------CGLYG 115 Query: 141 REPDLSSDIKEKFAQLSEE 159 K+ F + + Sbjct: 116 STTP-----KDNFLLFNRQ 129 >2BIG-A nrPDB Length = 361 Score = 28.0 bits (61), Expect = 2.4, Method: Composition-based stats. Identities = 9/47 (19%), Positives = 20/47 (42%), Gaps = 11/47 (23%) Query: 146 SSDIKEKFAQLSEEHGIV-----------RENIIDLTNANRCLEARE 181 + ++ ++F ++E G V R +I + + C+ RE Sbjct: 306 NEELNQQFLAKAKEQGFVGLNGHRSVGGCRASIYNAVPIDACIALRE 352 >2VYO-A nrPDB Length = 254 Score = 27.3 bits (59), Expect = 3.5, Method: Composition-based stats. Identities = 11/67 (16%), Positives = 24/67 (35%), Gaps = 8/67 (11%) Query: 115 DYDNYI--MIHLINKKDGETFQLMELYGREPDLSSDIKEKFAQLSEEHGIVRENIIDLTN 172 DYD+ + +I D + + L + + E ++ ++ G N Sbjct: 158 DYDDPVGEFESMIEGSDPKHHSFIILMHDGQEADTSRLENMVKIGKDKGYR------FVN 211 Query: 173 ANRCLEA 179 + CL+ Sbjct: 212 MDECLQG 218 >3LVG-A nrPDB Length = 624 Score = 26.9 bits (58), Expect = 4.6, Method: Composition-based stats. Identities = 11/42 (26%), Positives = 20/42 (47%) Query: 129 DGETFQLMELYGREPDLSSDIKEKFAQLSEEHGIVRENIIDL 170 DG+ F+L ++ G + +D E+ ++ G E I L Sbjct: 211 DGKEFRLAQMCGLHIVVHADELEELINYYQDRGYFEELITML 252 >1B89-A nrPDB Length = 449 Score = 26.9 bits (58), Expect = 4.8, Method: Composition-based stats. Identities = 11/42 (26%), Positives = 20/42 (47%) Query: 129 DGETFQLMELYGREPDLSSDIKEKFAQLSEEHGIVRENIIDL 170 DG+ F+L ++ G + +D E+ ++ G E I L Sbjct: 189 DGKEFRLAQMCGLHIVVHADELEELINYYQDRGYFEELITML 230 >1UYP-A nrPDB Length = 432 Score = 26.9 bits (58), Expect = 4.8, Method: Composition-based stats. Identities = 14/41 (34%), Positives = 21/41 (51%), Gaps = 1/41 (2%) Query: 11 GLTLVCVHAEEASSMERNFNVEKINGEWYTIMLATDKREKI 51 G ++ EE + R+ V + NGEW + L + K EKI Sbjct: 121 GNPVISKPPEEGTHAFRDPKVNRSNGEWRMV-LGSGKDEKI 160 >4MNU-A nrPDB Length = 153 Score = 26.1 bits (56), Expect = 8.7, Method: Composition-based stats. Identities = 7/27 (25%), Positives = 16/27 (59%) Query: 154 AQLSEEHGIVRENIIDLTNANRCLEAR 180 ++ E GI++E ++D+ +R +R Sbjct: 40 VRICENQGIIQEKLVDILKIDRTTASR 66 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.310 0.140 0.378 Lambda K H 0.267 0.0430 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 6,507,663 Number of Sequences: 36641 Number of extensions: 234610 Number of successful extensions: 1134 Number of sequences better than 10.0: 66 Number of HSP's better than 10.0 without gapping: 91 Number of HSP's successfully gapped in prelim test: 24 Number of HSP's that attempted gapping in prelim test: 952 Number of HSP's gapped (non-prelim): 116 length of query: 181 length of database: 10,336,785 effective HSP length: 91 effective length of query: 90 effective length of database: 7,002,454 effective search space: 630220860 effective search space used: 630220860 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 56 (26.1 bits)