BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q58634 (224 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 3H4P-a nrPDB 437 e-123 6HEC-1 nrPDB 203 4e-53 3IPM-H nrPDB 177 3e-45 5FMG-L nrPDB 110 5e-25 6EPC-1 nrPDB 109 9e-25 5LN3-5 nrPDB 108 3e-24 3UNF-K nrPDB 108 3e-24 3NZW-K nrPDB 108 3e-24 5L64-K nrPDB 107 4e-24 5L5A-K nrPDB 107 5e-24 5GJQ-a nrPDB 107 5e-24 6EPF-5 nrPDB 106 6e-24 6AVO-C nrPDB 106 8e-24 5CZ8-K nrPDB 106 1e-23 5LEZ-N nrPDB 103 6e-23 3UNB-K nrPDB 103 7e-23 5FMG-I nrPDB 102 2e-22 3H4P-A nrPDB 102 2e-22 5VFT-S nrPDB 100 9e-22 5L4G-U nrPDB 99 1e-21 6EPF-6 nrPDB 94 4e-20 3UNF-N nrPDB 93 8e-20 6AVO-A nrPDB 91 6e-19 6AVO-B nrPDB 88 3e-18 5FGI-H nrPDB 87 8e-18 5MPC-h nrPDB 86 1e-17 6J30-C nrPDB 84 3e-17 6HV7-H nrPDB 84 4e-17 3UNE-I nrPDB 84 4e-17 6EPF-2 nrPDB 84 4e-17 5L4G-8 nrPDB 83 8e-17 5FMG-E nrPDB 83 9e-17 3UNH-H nrPDB 82 1e-16 6HUB-H nrPDB 80 5e-16 2KU2-A nrPDB 80 1e-15 3NZW-L nrPDB 76 1e-14 1Q5Q-H nrPDB 76 1e-14 1Q5R-H nrPDB 75 2e-14 5FMG-C nrPDB 75 2e-14 5FMG-M nrPDB 74 5e-14 5FGE-J nrPDB 73 1e-13 3WXR-K nrPDB 72 2e-13 5LE5-B nrPDB 72 2e-13 1G0U-D nrPDB 71 3e-13 5FMG-H nrPDB 70 6e-13 6HE5-A nrPDB 70 7e-13 6EPD-G nrPDB 69 1e-12 2JAY-A nrPDB 68 3e-12 5FMG-J nrPDB 67 6e-12 5LEZ-C nrPDB 67 6e-12 5LF3-J nrPDB 66 1e-11 2Z5C-C nrPDB 66 1e-11 5LZP-A nrPDB 65 2e-11 4FZC-A nrPDB 64 4e-11 5GJR-F nrPDB 63 1e-10 6FVW-g nrPDB 59 1e-09 5FGG-F nrPDB 59 2e-09 5T0I-L nrPDB 58 3e-09 5FMG-D nrPDB 57 6e-09 6EPE-7 nrPDB 57 7e-09 6GOP-M nrPDB 56 1e-08 5LF6-M nrPDB 56 1e-08 5GJQ-g nrPDB 55 2e-08 5FMG-N nrPDB 52 3e-07 5LF0-A nrPDB 51 3e-07 1IRU-A nrPDB 49 2e-06 5FMG-G nrPDB 49 2e-06 4YA5-C nrPDB 48 3e-06 3NZW-E nrPDB 48 4e-06 5FMG-F nrPDB 40 0.001 5LOY-A nrPDB 39 0.001 4HO7-A nrPDB 35 0.038 5L5W-G nrPDB 33 0.14 5FMG-A nrPDB 32 0.25 5JI2-A nrPDB 31 0.39 4GBJ-A nrPDB 30 0.78 2D6F-A nrPDB 30 1.2 4CQD-A nrPDB 30 1.2 5CW8-A nrPDB 28 3.7 3UW2-A nrPDB 28 4.5 4P9S-A nrPDB 27 7.7 5B2N-A nrPDB 27 8.6 >3H4P-a nrPDB Length = 219 Score = 437 bits (1124), Expect = e-123, Method: Compositional matrix adjust. Identities = 218/218 (100%), Positives = 218/218 (100%) Query: 7 TTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIVRLLI 66 TTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIVRLLI Sbjct: 2 TTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIVRLLI 61 Query: 67 AEAKLYKMRTGRNIPPLACATLLSNILHSSRMFPFLTQIIIGGYDLLEGAKLFSLDPLGG 126 AEAKLYKMRTGRNIPPLACATLLSNILHSSRMFPFLTQIIIGGYDLLEGAKLFSLDPLGG Sbjct: 62 AEAKLYKMRTGRNIPPLACATLLSNILHSSRMFPFLTQIIIGGYDLLEGAKLFSLDPLGG 121 Query: 127 MNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERDTFSGNGISLAV 186 MNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERDTFSGNGISLAV Sbjct: 122 MNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERDTFSGNGISLAV 181 Query: 187 ITKDGVKIFEDEEIEKILDSMKAKPKKKTTKRSRRKSK 224 ITKDGVKIFEDEEIEKILDSMKAKPKKKTTKRSRRKSK Sbjct: 182 ITKDGVKIFEDEEIEKILDSMKAKPKKKTTKRSRRKSK 219 >6HEC-1 nrPDB Length = 202 Score = 203 bits (517), Expect = 4e-53, Method: Compositional matrix adjust. Identities = 103/202 (50%), Positives = 144/202 (71%), Gaps = 1/202 (0%) Query: 7 TTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIVRLLI 66 TTTVGL+C D V++AT+KRA++GN +A K AKK+Y+I D +AMT AGSVGDAQ + R++ Sbjct: 1 TTTVGLVCKDGVVMATEKRATMGNFIASKAAKKIYQIADRMAMTTAGSVGDAQFLARIIK 60 Query: 67 AEAKLYKMRTGRNIPPLACATLLSNILHSSRMFPFLTQIIIGGYDLLEGAKLFSLDPLGG 126 EA LY++R R A ATL SN+L+S R FP+L Q++IGG D EG ++S+DP+GG Sbjct: 61 IEANLYEIRRERKPTVRAIATLTSNLLNSYRYFPYLVQLLIGGID-SEGKSIYSIDPIGG 119 Query: 127 MNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERDTFSGNGISLAV 186 EEK ATGSGS AYGVLE + ++ V+E ++LA+ A+ SAM+RD+ SG+GI + Sbjct: 120 AIEEKDIVATGSGSLTAYGVLEDRFTPEIGVDEAVELAVRAIYSAMKRDSASGDGIDVVK 179 Query: 187 ITKDGVKIFEDEEIEKILDSMK 208 IT+D + EE+E+IL + Sbjct: 180 ITEDEFYQYSPEEVEQILAKFR 201 >3IPM-H nrPDB Length = 217 Score = 177 bits (449), Expect = 3e-45, Method: Compositional matrix adjust. Identities = 91/197 (46%), Positives = 132/197 (67%), Gaps = 4/197 (2%) Query: 6 GTTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIVRLL 65 GTTTVG+ DAVI+AT++R ++ N + K KKL++ID Y MTIAG VGDAQ +VR + Sbjct: 8 GTTTVGITLKDAVIMATERRVTMENFIMHKNGKKLFQIDTYTGMTIAGLVGDAQVLVRYM 67 Query: 66 IAEAKLYKMRTGRNIPPLACATLLSNILHSSRMFPFLTQIIIGGYDLLEGAKLFSLDPLG 125 AE +LY+++ N+P A ATLLSN+L+ + P++ Q+++GG D +FS+D G Sbjct: 68 KAELELYRLQRRVNMPIEAVATLLSNMLNQVKYMPYMVQLLVGGID--TAPHVFSIDAAG 125 Query: 126 GMNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERDTFSGNGISLA 185 G + E + +TGSGSP YGVLE+ Y M+V+EG+ L + A+ +A +RD+ SG I +A Sbjct: 126 G-SVEDIYASTGSGSPFVYGVLESQYSEKMTVDEGVDLVIRAISAAKQRDSASGGMIDVA 184 Query: 186 VIT-KDGVKIFEDEEIE 201 VIT KDG ++IE Sbjct: 185 VITRKDGYVQLPTDQIE 201 >5FMG-L nrPDB Length = 211 Score = 110 bits (275), Expect = 5e-25, Method: Compositional matrix adjust. Identities = 69/209 (33%), Positives = 114/209 (54%), Gaps = 4/209 (1%) Query: 7 TTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIVRLLI 66 TTT+ D +I+A D RAS+G+ ++ + +K+ +I+ I T+AG D + L Sbjct: 1 TTTLAFKFKDGIIVAVDSRASMGSFISSQNVEKIIEINKNILGTMAGGAADCLYWEKYLG 60 Query: 67 AEAKLYKMRTGRNIPPLACATLLSNILHSSRMFPFLTQIIIGGYDLLEGAKLFSLDPLGG 126 K+Y++R I A +T+LSNIL+ + + II+ GYD G +F +D G Sbjct: 61 KIIKIYELRNNEKISVRAASTILSNILYQYKGYGLCCGIILSGYD-HTGFNMFYVDDSGK 119 Query: 127 MNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERDTFSGNGISLAV 186 E F+ GSGS AY +L++ YD ++++++ ++LA NA+ A RD SG + + Sbjct: 120 KVEGNLFSC-GSGSTYAYSILDSAYDYNLNLDQAVELARNAIYHATFRDGGSGGKVRVFH 178 Query: 187 ITKDGV-KIFEDEEIEKILDSMKAKPKKK 214 I K+G KI E E++ L P++K Sbjct: 179 IHKNGYDKIIEGEDVFD-LHYHYTNPEQK 206 >6EPC-1 nrPDB Length = 238 Score = 109 bits (273), Expect = 9e-25, Method: Compositional matrix adjust. Identities = 71/214 (33%), Positives = 111/214 (51%), Gaps = 8/214 (3%) Query: 2 DVMKGTTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAI 61 +V GTT + + D V+L D R + G+ +A++ KL I D+I +GS D QA+ Sbjct: 29 EVSTGTTIMAVQFDGGVVLGADSRTTTGSYIANRVTDKLTPIHDHIFCCRSGSAADTQAV 88 Query: 62 VRLLIAEAKLYKMRTGRNIPPLA--CATLLSNILHSSRMFPFLTQIIIGGYDLLEGAKLF 119 + + + + N PPL A+L + + R + III G+D EG +++ Sbjct: 89 ADAVTYQLGFHSIEL--NEPPLVHTAASLFKEMCYRYRE-DLMAGIIIAGWDPQEGGQVY 145 Query: 120 SLDPLGGMNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERDTFSG 179 S+ P+GGM ++F GSGS YG ++A Y M+ +E ++ NAL AMERD SG Sbjct: 146 SV-PMGGMMVRQSFAIGGSGSSYIYGYVDATYREGMTKDECLQFTANALALAMERDGSSG 204 Query: 180 NGISLAVITKDGV--KIFEDEEIEKILDSMKAKP 211 I LA I + GV ++ ++I K+ S P Sbjct: 205 GVIRLAAIQQSGVERQVLLGDQIPKVTISTLPPP 238 >5LN3-5 nrPDB Length = 263 Score = 108 bits (269), Expect = 3e-24, Method: Compositional matrix adjust. Identities = 63/191 (32%), Positives = 103/191 (53%), Gaps = 2/191 (1%) Query: 1 MDVMKGTTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQA 60 ++++ GTTT+ VI+A D RA+ G +A + KK+ +I+ Y+ T+AG D Sbjct: 54 IEMLHGTTTLAFKFRHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAADCSF 113 Query: 61 IVRLLIAEAKLYKMRTGRNIPPLACATLLSNILHSSRMFPFLTQIIIGGYDLLEGAKLFS 120 RLL + ++Y++R I A + LL+N+++ + +I G+D G L+ Sbjct: 114 WERLLARQCRIYELRNKERISVAAASKLLANMVYQYKGMGLSMGTMICGWD-KRGPGLYY 172 Query: 121 LDPLGGMNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERDTFSGN 180 +D G TF+ GSGS AYGV++ GY D+ VE+ LA A+ A RD +SG Sbjct: 173 VDSEGNRISGATFS-VGSGSVYAYGVMDRGYSYDLEVEQAYDLARRAIYQATYRDAYSGG 231 Query: 181 GISLAVITKDG 191 ++L + +DG Sbjct: 232 AVNLYHVREDG 242 >3UNF-K nrPDB Length = 204 Score = 108 bits (269), Expect = 3e-24, Method: Compositional matrix adjust. Identities = 65/198 (32%), Positives = 105/198 (53%), Gaps = 2/198 (1%) Query: 7 TTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIVRLLI 66 TTT+ VI+A D RA+ G+ ++ K+ +I+ Y+ T++G D Q RLL Sbjct: 1 TTTLAFKFQHGVIVAVDSRATAGSYISSLRMNKVIEINPYLLGTMSGCAADCQYWERLLA 60 Query: 67 AEAKLYKMRTGRNIPPLACATLLSNILHSSRMFPFLTQIIIGGYDLLEGAKLFSLDPLGG 126 E +LY +R G I A + LLSN++ R +I G+D +G L+ +D G Sbjct: 61 KECRLYYLRNGERISVSAASKLLSNMMLQYRGMGLSMGSMICGWD-KKGPGLYYVDDNGT 119 Query: 127 MNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERDTFSGNGISLAV 186 + F+ TGSG+ AYGV+++GY +D+S EE L A+ A RD +SG +++ Sbjct: 120 RLSGQMFS-TGSGNTYAYGVMDSGYRQDLSPEEAYDLGRRAIAYATHRDNYSGGVVNMYH 178 Query: 187 ITKDGVKIFEDEEIEKIL 204 + +DG E ++ +L Sbjct: 179 MKEDGWVKVESSDVSDLL 196 >3NZW-K nrPDB Length = 287 Score = 108 bits (269), Expect = 3e-24, Method: Compositional matrix adjust. Identities = 61/206 (29%), Positives = 109/206 (52%), Gaps = 1/206 (0%) Query: 3 VMKGTTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIV 62 + GTTT+ +I+A D RA+ GN VA + KK+ +I+ ++ T+AG D Q Sbjct: 72 IAHGTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWE 131 Query: 63 RLLIAEAKLYKMRTGRNIPPLACATLLSNILHSSRMFPFLTQIIIGGYDLLEGAKLFSLD 122 L ++ +L+++R I A + +LSN+++ + +I GY EG ++ +D Sbjct: 132 TWLGSQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMICGYTRKEGPTIYYVD 191 Query: 123 PLGGMNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERDTFSGNGI 182 G + F GSG AYGVL++ Y D+SVE+ + L ++ +A RD +SG + Sbjct: 192 SDGTRLKGDIF-CVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSV 250 Query: 183 SLAVITKDGVKIFEDEEIEKILDSMK 208 +L +T+DG + ++ ++ +K Sbjct: 251 NLYHVTEDGWIYHGNHDVGELFWKVK 276 >5L64-K nrPDB Length = 211 Score = 107 bits (268), Expect = 4e-24, Method: Compositional matrix adjust. Identities = 63/202 (31%), Positives = 108/202 (53%), Gaps = 2/202 (0%) Query: 7 TTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIVRLLI 66 TTT+ VI+A D RA+ G +A + KK+ +I+ Y+ T+AG D RLL Sbjct: 1 TTTLAFKFRHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAADCSFWERLLA 60 Query: 67 AEAKLYKMRTGRNIPPLACATLLSNILHSSRMFPFLTQIIIGGYDLLEGAKLFSLDPLGG 126 + ++Y++R I A + LL+N+++ + +I G+D G L+ +D G Sbjct: 61 RQCRIYELRNKERISVAAASKLLANMVYQYKGMGLSMGTMICGWD-KRGPGLYYVDSEGN 119 Query: 127 MNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERDTFSGNGISLAV 186 TF+ GSGS AYGVL++ Y D+SVE+ + L ++ +A RD +SG ++L Sbjct: 120 RISGATFS-VGSGSVYAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSVNLYH 178 Query: 187 ITKDGVKIFEDEEIEKILDSMK 208 +T+DG + ++ ++ +K Sbjct: 179 VTEDGWIYHGNHDVGELFWKVK 200 >5L5A-K nrPDB Length = 211 Score = 107 bits (267), Expect = 5e-24, Method: Compositional matrix adjust. Identities = 65/202 (32%), Positives = 106/202 (52%), Gaps = 2/202 (0%) Query: 7 TTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIVRLLI 66 TTT+ VI A D RAS G+ ++ K+ +I+ Y+ T++G D Q LL Sbjct: 1 TTTLAFKFQHGVIAAVDSRASAGSYISALRVNKVIEINPYLLGTMSGCAADCQYWETLLA 60 Query: 67 AEAKLYKMRTGRNIPPLACATLLSNILHSSRMFPFLTQIIIGGYDLLEGAKLFSLDPLGG 126 E +LY +R G I A + LLSN++ R +I G+D +G L+ +D G Sbjct: 61 KECRLYYLRNGERISVSAASKLLSNMMCQYRGMGLSMGSMICGWD-KKGPGLYYVDEHGT 119 Query: 127 MNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERDTFSGNGISLAV 186 F+ TGSG+ AYGVL++ Y D+SVE+ + L ++ +A RD +SG ++L Sbjct: 120 RLSGNMFS-TGSGNTYAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSVNLYH 178 Query: 187 ITKDGVKIFEDEEIEKILDSMK 208 +T+DG + ++ ++ +K Sbjct: 179 VTEDGWIYHGNHDVGELFWKVK 200 >5GJQ-a nrPDB Length = 239 Score = 107 bits (267), Expect = 5e-24, Method: Compositional matrix adjust. Identities = 68/194 (35%), Positives = 102/194 (52%), Gaps = 6/194 (3%) Query: 2 DVMKGTTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAI 61 +V GTT + + D V+L D R + G+ +A++ KL I D I +GS D QA+ Sbjct: 30 EVSTGTTIMAVQFDGGVVLGADSRTTTGSYIANRVTDKLTPIHDRIFCCRSGSAADTQAV 89 Query: 62 VRLLIAEAKLYKMRTGRNIPPLA--CATLLSNILHSSRMFPFLTQIIIGGYDLLEGAKLF 119 + + + + N PPL A+L + + R + III G+D EG +++ Sbjct: 90 ADAVTYQLGFHSIEL--NEPPLVHTAASLFKEMCYRYRE-DLMAGIIIAGWDPQEGGQVY 146 Query: 120 SLDPLGGMNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERDTFSG 179 S+ P+GGM ++F GSGS YG ++A Y M+ EE ++ NAL AMERD SG Sbjct: 147 SV-PMGGMMVRQSFAIGGSGSSYIYGYVDATYREGMTKEECLQFTANALALAMERDGSSG 205 Query: 180 NGISLAVITKDGVK 193 I LA I + GV+ Sbjct: 206 GVIRLAAIAESGVE 219 >6EPF-5 nrPDB Length = 263 Score = 106 bits (265), Expect = 6e-24, Method: Compositional matrix adjust. Identities = 63/205 (30%), Positives = 106/205 (51%), Gaps = 2/205 (0%) Query: 1 MDVMKGTTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQA 60 ++++ GTTT+ VI+A D RA+ G +A + KK+ +I+ Y+ T+AG D Sbjct: 54 IEMLHGTTTLAFKFQHGVIVAADSRATAGPYIASQTVKKVIEINPYLLGTMAGGAADCSF 113 Query: 61 IVRLLIAEAKLYKMRTGRNIPPLACATLLSNILHSSRMFPFLTQIIIGGYDLLEGAKLFS 120 RLL + ++Y++R I A + LL+N+++ + +I G+D G L+ Sbjct: 114 WERLLARQCRIYELRNKERISVAAASKLLANMVYQYKGMGLSMGTMICGWD-KRGPGLYY 172 Query: 121 LDPLGGMNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERDTFSGN 180 +D G F+ GSGS A+GV++ GY D+ VEE LA A+ A RD +SG Sbjct: 173 VDSEGNRISGTAFS-VGSGSVYAFGVMDRGYSYDLQVEEAYDLARRAIYQATYRDAYSGG 231 Query: 181 GISLAVITKDGVKIFEDEEIEKILD 205 ++L + +DG + + + D Sbjct: 232 AVNLYHVREDGWIRVSSDNVADLHD 256 >6AVO-C nrPDB Length = 204 Score = 106 bits (264), Expect = 8e-24, Method: Compositional matrix adjust. Identities = 65/202 (32%), Positives = 104/202 (51%), Gaps = 2/202 (0%) Query: 7 TTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIVRLLI 66 TTT+ VI A D RAS G+ ++ K+ +I+ Y+ T++G D Q RLL Sbjct: 1 TTTLAFKFQHGVIAAVDSRASAGSYISALRVNKVIEINPYLLGTMSGCAADCQYWERLLA 60 Query: 67 AEAKLYKMRTGRNIPPLACATLLSNILHSSRMFPFLTQIIIGGYDLLEGAKLFSLDPLGG 126 E +LY +R G I A + LLSN++ R +I G+D +G L+ +D G Sbjct: 61 KECRLYYLRNGERISVSAASKLLSNMMCQYRGMGLSMGSMICGWD-KKGPGLYYVDEHGT 119 Query: 127 MNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERDTFSGNGISLAV 186 F+ TGSG+ AYGV+++GY ++S EE L A+ A RD++SG +++ Sbjct: 120 RLSGNMFS-TGSGNTYAYGVMDSGYRPNLSPEEAYDLGRRAIAYATHRDSYSGGVVNMYH 178 Query: 187 ITKDGVKIFEDEEIEKILDSMK 208 + +DG E ++ +L + Sbjct: 179 MKEDGWVKVESTDVSDLLHQYR 200 >5CZ8-K nrPDB Length = 221 Score = 106 bits (264), Expect = 1e-23, Method: Compositional matrix adjust. Identities = 60/208 (28%), Positives = 109/208 (52%), Gaps = 1/208 (0%) Query: 1 MDVMKGTTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQA 60 + + GTTT+ +I+A D RA+ GN VA + K + +I+ ++ T+AG D Q Sbjct: 4 IKIAHGTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKAVIEINPFLLGTMAGGAADCQF 63 Query: 61 IVRLLIAEAKLYKMRTGRNIPPLACATLLSNILHSSRMFPFLTQIIIGGYDLLEGAKLFS 120 L ++ +L+++R I A + +LSN+++ + +I GY EG ++ Sbjct: 64 WETWLGSQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMICGYTRKEGPTIYY 123 Query: 121 LDPLGGMNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERDTFSGN 180 +D G + F GSG AYGVL++ Y D+SVE+ + L ++ +A RD +SG Sbjct: 124 VDSDGTRLKGDIF-CVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGG 182 Query: 181 GISLAVITKDGVKIFEDEEIEKILDSMK 208 ++L +T+DG + ++ ++ +K Sbjct: 183 SVNLYHVTEDGWIYHGNHDVGELFWKVK 210 >5LEZ-N nrPDB Length = 205 Score = 103 bits (257), Expect = 6e-23, Method: Compositional matrix adjust. Identities = 66/189 (34%), Positives = 99/189 (52%), Gaps = 6/189 (3%) Query: 7 TTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIVRLLI 66 TT + + D V+L D R + G+ +A++ KL I D I +GS D QA+ + Sbjct: 1 TTIMAVQFDGGVVLGADSRTTTGSYIANRVTDKLTPIHDRIFCCRSGSAADTQAVADAVT 60 Query: 67 AEAKLYKMRTGRNIPPLA--CATLLSNILHSSRMFPFLTQIIIGGYDLLEGAKLFSLDPL 124 + + + N PPL A+L + + R + III G+D EG +++S+ P+ Sbjct: 61 YQLGFHSIEL--NEPPLVHTAASLFKEMCYRYRE-DLMAGIIIAGWDPQEGGQVYSV-PM 116 Query: 125 GGMNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERDTFSGNGISL 184 GGM ++F GSGS YG ++A Y M+ EE ++ NAL AMERD SG I L Sbjct: 117 GGMMVRQSFAIGGSGSSYIYGYVDATYREGMTKEECLQFTANALALAMERDGSSGGVIRL 176 Query: 185 AVITKDGVK 193 A I + GV+ Sbjct: 177 AAIAESGVE 185 >3UNB-K nrPDB Length = 205 Score = 103 bits (256), Expect = 7e-23, Method: Compositional matrix adjust. Identities = 63/199 (31%), Positives = 101/199 (50%), Gaps = 2/199 (1%) Query: 7 TTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIVRLLI 66 TTT+ VI+A D RA+ G +A + KK+ +I+ Y+ T+AG D RLL Sbjct: 1 TTTLAFKFLHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAADCSFWERLLA 60 Query: 67 AEAKLYKMRTGRNIPPLACATLLSNILHSSRMFPFLTQIIIGGYDLLEGAKLFSLDPLGG 126 + ++Y++R I A + LL+N+++ + +I G+D G L+ +D G Sbjct: 61 RQCRIYELRNKERISVAAASKLLANMVYQYKGMGLSMGTMICGWD-KRGPGLYYVDSEGN 119 Query: 127 MNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERDTFSGNGISLAV 186 F+ GSGS AYGV++ GY D+ VEE LA A+ A RD +SG ++L Sbjct: 120 RISGTAFS-VGSGSVYAYGVMDRGYSYDLKVEEAYDLARRAIYQATYRDAYSGGAVNLYH 178 Query: 187 ITKDGVKIFEDEEIEKILD 205 + +DG + + + D Sbjct: 179 VREDGWIRVSSDNVADLHD 197 >5FMG-I nrPDB Length = 229 Score = 102 bits (253), Expect = 2e-22, Method: Compositional matrix adjust. Identities = 66/187 (35%), Positives = 97/187 (51%), Gaps = 3/187 (1%) Query: 7 TTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIVRLLI 66 TT GL+C +AVIL D RA+ G +VADK KL+ I I AG GD + L Sbjct: 1 TTICGLVCQNAVILGADTRATEGPIVADKNCSKLHYISKNIWCAGAGVAGDLEHTTLWLQ 60 Query: 67 AEAKLYKMRTGRNIPPLACATLLSNILHSSRMFPFLTQIIIGGYDLLEGAKLFSLDPLGG 126 +L+++ T C + L+ L + + + I++GG D + G +L+ + P G Sbjct: 61 HNVELHRLNTNTQPRVSMCVSRLTQELFKYQGYK-VCAIVLGGVD-VNGPQLYGIHPHGS 118 Query: 127 MNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERDTFSGNGISLAV 186 + FTA GSGS A VLEA Y +M++EEG L A+ + + D SG + + V Sbjct: 119 -SCLLPFTALGSGSLNAMAVLEAKYRDNMTIEEGKNLVCEAICAGIFNDLGSGGNVDICV 177 Query: 187 ITKDGVK 193 ITKD + Sbjct: 178 ITKDSYQ 184 >3H4P-A nrPDB Length = 264 Score = 102 bits (253), Expect = 2e-22, Method: Compositional matrix adjust. Identities = 62/175 (35%), Positives = 99/175 (56%), Gaps = 7/175 (4%) Query: 3 VMKGTTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIV 62 V +GTT +G+ C D V+LA D+R + LV + +K+++IDD++A +G V DA+ ++ Sbjct: 35 VRRGTTAIGIACKDGVVLAVDRRIT-SKLVKIRSIEKIFQIDDHVAAATSGLVADARVLI 93 Query: 63 RLLIAEAKLYKMRTGRNIPPLACATLLSNILHSSRMF----PFLTQIIIGGYDLLEGAKL 118 EA++Y++ G I A + +I + PF ++I G D E A+L Sbjct: 94 DRARLEAQIYRLTYGEEISIEMLAKKICDIKQAYTQHGGVRPFGVSLLIAGIDKNE-ARL 152 Query: 119 FSLDPLGGMNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAME 173 F DP G + E K TA GSG P+ +LE Y D++++EG++LA+ AL A E Sbjct: 153 FETDPSGALIEYKA-TAIGSGRPVVMELLEKEYRDDITLDEGLELAITALTKANE 206 >5VFT-S nrPDB Length = 213 Score = 99.8 bits (247), Expect = 9e-22, Method: Compositional matrix adjust. Identities = 59/200 (29%), Positives = 104/200 (52%), Gaps = 10/200 (5%) Query: 3 VMKGTTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIV 62 V G T + + +D I+A+D R S G + +++ K YK+ D + +G GD + Sbjct: 6 VFNGGTILAIAGEDFAIVASDTRLSEGFSIHTRDSPKCYKLTDKTVIGCSGFHGDCLTLT 65 Query: 63 RLLIAEAKLYKMRTGRNIPPLACATLLSNILHSSRMFPFLTQIIIGGYDLLEGAKLFSLD 122 +++ A K+YK + + A A +LS IL+S R FP+ IIGG D ++S D Sbjct: 66 KIIEARLKMYKHSNNKAMTTGAIAAMLSTILYSRRFFPYYVYNIIGGLDEEGKGAVYSFD 125 Query: 123 PLGGMNEEKTFTATGSGSPIAYGVL--EAGYDRDMSVEE-------GIKLALNALKSAME 173 P+G + +F A GS S + +L + G+ +VE ++L + SA E Sbjct: 126 PVGSYQRD-SFKAGGSASAMLQPLLDNQVGFKNMQNVEHVPLSLDRAMRLVKDVFISAAE 184 Query: 174 RDTFSGNGISLAVITKDGVK 193 RD ++G+ + + ++TK+G++ Sbjct: 185 RDVYTGDALRICIVTKEGIR 204 >5L4G-U nrPDB Length = 241 Score = 99.4 bits (246), Expect = 1e-21, Method: Compositional matrix adjust. Identities = 59/200 (29%), Positives = 104/200 (52%), Gaps = 10/200 (5%) Query: 3 VMKGTTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIV 62 V G T + + +D I+A+D R S G + +++ K YK+ D + +G GD + Sbjct: 34 VFNGGTILAIAGEDFAIVASDTRLSEGFSIHTRDSPKCYKLTDKTVIGCSGFHGDCLTLT 93 Query: 63 RLLIAEAKLYKMRTGRNIPPLACATLLSNILHSSRMFPFLTQIIIGGYDLLEGAKLFSLD 122 +++ A K+YK + + A A +LS IL+S R FP+ IIGG D ++S D Sbjct: 94 KIIEARLKMYKHSNNKAMTTGAIAAMLSTILYSRRFFPYYVYNIIGGLDEEGKGAVYSFD 153 Query: 123 PLGGMNEEKTFTATGSGSPIAYGVL--EAGYDRDMSVEE-------GIKLALNALKSAME 173 P+G + +F A GS S + +L + G+ +VE ++L + SA E Sbjct: 154 PVGSYQRD-SFKAGGSASAMLQPLLDNQVGFKNMQNVEHVPLSLDRAMRLVKDVFISAAE 212 Query: 174 RDTFSGNGISLAVITKDGVK 193 RD ++G+ + + ++TK+G++ Sbjct: 213 RDVYTGDALRICIVTKEGIR 232 >6EPF-6 nrPDB Length = 240 Score = 94.4 bits (233), Expect = 4e-20, Method: Compositional matrix adjust. Identities = 57/199 (28%), Positives = 102/199 (51%), Gaps = 10/199 (5%) Query: 4 MKGTTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIVR 63 G T + + +D I+A+D R S G + +++ K YK+ D + +G GD + + Sbjct: 34 FNGGTVLAIAGEDFSIVASDTRLSEGFSIHTRDSPKCYKLTDKTVIGCSGFHGDCLTLTK 93 Query: 64 LLIAEAKLYKMRTGRNIPPLACATLLSNILHSSRMFPFLTQIIIGGYDLLEGAKLFSLDP 123 ++ A K+YK + + A A +LS IL+S R FP+ II G D ++S DP Sbjct: 94 IIEARLKMYKHSNNKAMTTGAIAAMLSTILYSRRFFPYYVYNIIEGLDEEGKGAVYSFDP 153 Query: 124 LGGMNEEKTFTATGSGSPIAYGVL--EAGYDRDMSVEE-------GIKLALNALKSAMER 174 +G + +F A GS S + +L + G+ +VE ++L + SA ER Sbjct: 154 VGSYQRD-SFKAGGSASAMLQPLLDNQVGFKNMQNVEHVPLTLDRAMRLVKDVFISAAER 212 Query: 175 DTFSGNGISLAVITKDGVK 193 D ++G+ + + ++TK+G++ Sbjct: 213 DVYTGDALRICIVTKEGIR 231 >3UNF-N nrPDB Length = 199 Score = 93.2 bits (230), Expect = 8e-20, Method: Compositional matrix adjust. Identities = 68/203 (33%), Positives = 100/203 (49%), Gaps = 9/203 (4%) Query: 7 TTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIVRLLI 66 TT + + D V++ +D R S G V ++ KL + I ++GS DAQAI + Sbjct: 1 TTIMAVEFDGGVVVGSDSRVSAGTAVVNRVFDKLSPLHQRIFCALSGSAADAQAIADM-- 58 Query: 67 AEAKLYKMRTGRNIPPL--ACATLLSNILHSSRMFPFLTQIIIGGYDLLEGAKLFSLDPL 124 A +L PPL A A ++ NI + R L +I+ G+D EG +++ + Sbjct: 59 AAYQLELHGLELEEPPLVLAAANVVKNISYKYRE-DLLAHLIVAGWDQREGGQVYGT--M 115 Query: 125 GGMNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERDTFSGNGISL 184 GGM + FT GSGS YG ++A Y M+ EE + NA+ AM RD SG I L Sbjct: 116 GGMLIRQPFTIGGSGSSYIYGYVDAAYKPGMTPEECRRFTTNAITLAMNRDGSSGGVIYL 175 Query: 185 AVITKDGV--KIFEDEEIEKILD 205 IT GV ++ +E+ K D Sbjct: 176 VTITAAGVDHRVILGDELPKFYD 198 >6AVO-A nrPDB Length = 199 Score = 90.5 bits (223), Expect = 6e-19, Method: Compositional matrix adjust. Identities = 64/203 (31%), Positives = 100/203 (49%), Gaps = 9/203 (4%) Query: 7 TTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIVRLLI 66 TT + + D V++ +D R S G V ++ KL + + I ++GS DAQA+ + Sbjct: 1 TTIMAVEFDGGVVMGSDSRVSAGEAVVNRVFDKLSPLHERIYCALSGSAADAQAVADMAA 60 Query: 67 AEAKLYKMRTGRNIPPL--ACATLLSNILHSSRMFPFLTQIIIGGYDLLEGAKLFSLDPL 124 + +L+ + PPL A A ++ NI + R +++ G+D EG +++ L Sbjct: 61 YQLELHGIELEE--PPLVLAAANVVRNISYKYRE-DLSAHLMVAGWDQREGGQVYGT--L 115 Query: 125 GGMNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERDTFSGNGISL 184 GGM + F GSGS YG ++A Y MS EE + +A+ AM RD SG I L Sbjct: 116 GGMLTRQPFAIGGSGSTFIYGYVDAAYKPGMSPEECRRFTTDAIALAMSRDGSSGGVIYL 175 Query: 185 AVITKDGV--KIFEDEEIEKILD 205 IT GV ++ E+ K D Sbjct: 176 VTITAAGVDHRVILGNELPKFYD 198 >6AVO-B nrPDB Length = 234 Score = 88.2 bits (217), Expect = 3e-18, Method: Compositional matrix adjust. Identities = 65/193 (33%), Positives = 100/193 (51%), Gaps = 11/193 (5%) Query: 7 TTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIVRLLI 66 TT GL+ D VIL D RA+ ++VADK +K++ I I AG DA+ R++ Sbjct: 1 TTIAGLVFQDGVILGADTRATNDSVVADKSCEKIHFIAPKIYCCGAGVAADAEMTTRMVA 60 Query: 67 AEAKLYKMRTGRNIPPLACATLLSNILHSSRMFPFLTQI----IIGGYDLLEGAKLFSLD 122 ++ +L+ + TGR P +A T IL + +F + + I+GG D L G +L+ + Sbjct: 61 SKMELHALSTGRE-PRVATVT---RILRQT-LFRYQGHVGASLIVGGVD-LTGPQLYGVH 114 Query: 123 PLGGMNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERDTFSGNGI 182 P G + FTA GSG A VLE + +M++E L + A+ + + D SG + Sbjct: 115 PHGSYSRLP-FTALGSGQDAALAVLEDRFQPNMTLEAAQGLLVEAVTAGILGDLGSGGNV 173 Query: 183 SLAVITKDGVKIF 195 VITK G K+ Sbjct: 174 DACVITKTGAKLL 186 >5FGI-H nrPDB Length = 244 Score = 86.7 bits (213), Expect = 8e-18, Method: Compositional matrix adjust. Identities = 56/186 (30%), Positives = 100/186 (53%), Gaps = 11/186 (5%) Query: 6 GTTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIVRLL 65 G T VG+ ++ V++A D R++ G +VADK KL++I I AG+ D +A+ +L+ Sbjct: 12 GATIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEAVTQLI 71 Query: 66 IAEAKLYKMRTGRNIPPLACATLLSNILHSSRMFPFLTQI----IIGGYDLLEGAKLFSL 121 + +L+ + T R ++ +L +F + I I+ G D G+ LFS+ Sbjct: 72 GSNIELHSLYTSREPRVVSALQMLKQ-----HLFKYQGHIGAYLIVAGVDPT-GSHLFSI 125 Query: 122 DPLGGMNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERDTFSGNG 181 G + + + GSGS A VLE+ + +D++ EE IKLA +A+++ + D SG+ Sbjct: 126 HAHGS-TDVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDLGSGSN 184 Query: 182 ISLAVI 187 + + V+ Sbjct: 185 VDVCVM 190 >5MPC-h nrPDB Length = 215 Score = 85.5 bits (210), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 60/204 (29%), Positives = 98/204 (48%), Gaps = 5/204 (2%) Query: 2 DVMKGTTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAI 61 +V GT+ + + D VIL D R + G +A++ KL ++ D I +GS D QAI Sbjct: 15 EVSLGTSIMAVTFKDGVILGADSRTTTGAYIANRVTDKLTRVHDKIWCCRSGSAADTQAI 74 Query: 62 VRLLIAEAKLYKMRTGRNIPPLACATLLSNILHSSRMFPFLTQIIIGGYDLLEGAKLFSL 121 ++ +LY + G P A + L II+ GYD +++++ Sbjct: 75 ADIVQYHLELYTSQYG--TPSTETAASVFKELCYENKDNLTAGIIVAGYDDKNKGEVYTI 132 Query: 122 DPLGGMNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERDTFSGNG 181 PLGG + + GSGS YG + + +MS EE + ++L A++ D SG Sbjct: 133 -PLGGSVHKLPYAIAGSGSTFIYGYCDKNFRENMSKEETVDFIKHSLSQAIKWDGSSGGV 191 Query: 182 ISLAVITKDGVK--IFEDEEIEKI 203 I + V+T GV+ IF +E E++ Sbjct: 192 IRMVVLTAAGVERLIFYPDEYEQL 215 >6J30-C nrPDB Length = 258 Score = 84.3 bits (207), Expect = 3e-17, Method: Compositional matrix adjust. Identities = 60/207 (28%), Positives = 100/207 (48%), Gaps = 11/207 (5%) Query: 8 TTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIVRLLIA 67 T +G++ D ++LA +++ + L D +KLYK++D IA+ +AG DA+ ++ Sbjct: 34 TAIGIMASDGIVLAAERKVTSTLLEQDTSTEKLYKLNDKIAVAVAGLTADAEILINTARI 93 Query: 68 EAKLYKMRTGRNIPPLACATLLSNI----LHSSRMFPFLTQIIIGGYDLLEGAKLFSLDP 123 A+ Y +IP LS+I + PF I GYD G +L++ +P Sbjct: 94 HAQNYLKTYNEDIPVEILVRRLSDIKQGYTQHGGLRPFGVSFIYAGYDDRYGYQLYTSNP 153 Query: 124 LGGMNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERDTFSGNGIS 183 G K + G+ + A +L+ Y DM V++ I+LAL L + + + + Sbjct: 154 SGNYTGWKAISV-GANTSAAQTLLQMDYKDDMKVDDAIELALKTLSKTTDSSALTYDRLE 212 Query: 184 LAVITK---DG---VKIFEDEEIEKIL 204 A I K DG KIF+ +EI+ IL Sbjct: 213 FATIRKGANDGEVYQKIFKPQEIKDIL 239 >6HV7-H nrPDB Length = 226 Score = 84.3 bits (207), Expect = 4e-17, Method: Compositional matrix adjust. Identities = 58/185 (31%), Positives = 98/185 (52%), Gaps = 11/185 (5%) Query: 7 TTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIVRLLI 66 TT GL+ D VIL D RA+ ++VADK +K++ I I AG DA+A+ +L+ Sbjct: 1 TTIAGLVFQDGVILGADTRATNDSVVADKSCEKIHFIAPKIYCCGAGVAADAEAVTQLIG 60 Query: 67 AEAKLYKMRTGRNIPPLACATLLSNILHSSRMFPFLTQI----IIGGYDLLEGAKLFSLD 122 + +L+ + T R ++ +L +F + I I+ G D G+ LFS+ Sbjct: 61 SNIELHSLYTSREPRVVSALQMLKQ-----HLFKYQGHIGAYLIVAGVD-PTGSHLFSIH 114 Query: 123 PLGGMNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERDTFSGNGI 182 G + + + GSGS A VLE+ + +D++ EE IKLA +A+++ + D SG+ + Sbjct: 115 AHGS-TDVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDLGSGSNV 173 Query: 183 SLAVI 187 + V+ Sbjct: 174 DVCVM 178 >3UNE-I nrPDB Length = 205 Score = 84.3 bits (207), Expect = 4e-17, Method: Compositional matrix adjust. Identities = 50/182 (27%), Positives = 93/182 (51%), Gaps = 9/182 (4%) Query: 16 DAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIVRLLIAEAKLYKMR 75 + V +A D+R + + + +K++ + D + + +AG D Q + + L LY+++ Sbjct: 18 NCVAIAADRRFGIQAQMVTTDFQKIFPMGDRLYIGLAGLATDVQTVAQRLKFRLNLYELK 77 Query: 76 TGRNIPPLACATLLSNILHSSRMFPFLTQIIIGGYDLLEGAKLF-----SLDPLGGMNEE 130 GR I P ++++N+L+ R P+ T+ +I G D K F SLD +G Sbjct: 78 EGRQIKPYTLMSMVANLLYEKRFGPYYTEPVIAGLD----PKTFKPFICSLDLIGCPMVT 133 Query: 131 KTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERDTFSGNGISLAVITKD 190 F +G+ S YG+ E+ ++ +M E + A+ +A++RD SG G+ + VI KD Sbjct: 134 DDFVVSGTCSEQMYGMCESLWEPNMDPEHLFETISQAMLNAVDRDAVSGMGVIVHVIEKD 193 Query: 191 GV 192 + Sbjct: 194 KI 195 >6EPF-2 nrPDB Length = 277 Score = 84.0 bits (206), Expect = 4e-17, Method: Compositional matrix adjust. Identities = 64/220 (29%), Positives = 105/220 (47%), Gaps = 15/220 (6%) Query: 6 GTTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIVRLL 65 GTT G++ D ++L D RA+ G +VADK K++ I I AG+ D +L+ Sbjct: 43 GTTIAGVVYKDGIVLGADTRATEGMVVADKNCSKIHFISPNIYCCGAGTAADTDMTTQLI 102 Query: 66 IAEAKLYKMRTGRNIPPLACAT-LLSNILHSSRMFPFLTQIIIGGYDLLEGAKLFSLDPL 124 + +L+ + TGR +P + A +L +L + + +++GG D + G L+S+ P Sbjct: 103 SSNLELHSLTTGR-LPRVVTANRMLKQMLFRYQGY-IGAALVLGGVD-VTGPHLYSIYPH 159 Query: 125 GGMNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERDTFSGNGISL 184 G ++ + GSGS A V E + DM EE KL A+ + + D SG+ I L Sbjct: 160 GS-TDKLPYVTMGSGSLAAMAVFEDKFRPDMEEEEAKKLVSEAIAAGIFNDLGSGSNIDL 218 Query: 185 AVITKDGVKIFEDEEIEKILDSMKAKPKKKTTKRSRRKSK 224 VI+K + + P KK T+ R + + Sbjct: 219 CVISKSKLDFLRPYSV----------PNKKGTRFGRYRCE 248 >5L4G-8 nrPDB Length = 277 Score = 83.2 bits (204), Expect = 8e-17, Method: Compositional matrix adjust. Identities = 63/220 (28%), Positives = 105/220 (47%), Gaps = 15/220 (6%) Query: 6 GTTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIVRLL 65 GTT G++ D ++L D RA+ G +VADK K++ I I AG+ D +L+ Sbjct: 43 GTTIAGVVYKDGIVLGADTRATEGMVVADKNCSKIHFISPNIYCCGAGTAADTDMTTQLI 102 Query: 66 IAEAKLYKMRTGRNIPPLACAT-LLSNILHSSRMFPFLTQIIIGGYDLLEGAKLFSLDPL 124 + +L+ + TGR +P + A +L +L + + +++GG D + G L+S+ P Sbjct: 103 SSNLELHSLSTGR-LPRVVTANRMLKQMLFRYQGY-IGAALVLGGVD-VTGPHLYSIYPH 159 Query: 125 GGMNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERDTFSGNGISL 184 G ++ + GSGS A V E + DM EE L A+ + + D SG+ I L Sbjct: 160 GS-TDKLPYVTMGSGSLAAMAVFEDKFRPDMEEEEAKNLVSEAIAAGIFNDLGSGSNIDL 218 Query: 185 AVITKDGVKIFEDEEIEKILDSMKAKPKKKTTKRSRRKSK 224 VI+K+ + + P KK T+ R + + Sbjct: 219 CVISKNKLDFLRPYTV----------PNKKGTRLGRYRCE 248 >5FMG-E nrPDB Length = 256 Score = 83.2 bits (204), Expect = 9e-17, Method: Compositional matrix adjust. Identities = 64/217 (29%), Positives = 105/217 (48%), Gaps = 17/217 (7%) Query: 6 GTTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIVRLL 65 G+T VG+ +D VILA+++R S L+ +KL IDD+I ++G + DA+ ++ Sbjct: 34 GSTAVGICVNDGVILASERRIS-STLIEKDSVEKLLSIDDHIGCAMSGLMADARTLIDYA 92 Query: 66 IAEAKLYKMRTGRNIPPLACATLL-------SNILHSSR----MFPFLTQIIIGGYDLLE 114 E YK NI +C L+ SN+ S R PF ++IGG D Sbjct: 93 RVECNHYKFIYNENINIKSCVELISELALDFSNLSDSKRKKIMSRPFGVALLIGGVD-KN 151 Query: 115 GAKLFSLDPLGGMNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMER 174 G L+ +P G N + + GS A +L+ Y +DM+ E+ LAL L+ ME Sbjct: 152 GPCLWYTEP-SGTNTRFSAASIGSAQEGAELLLQENYKKDMTFEQAEILALTVLRQVME- 209 Query: 175 DTFSGNGISLAVITKDGVKIFE--DEEIEKILDSMKA 209 D S + + + I K ++ ++I +I+D + + Sbjct: 210 DKLSTSNVEICAIKKSDQTFYKYNTDDISRIIDVLPS 246 >3UNH-H nrPDB Length = 234 Score = 82.4 bits (202), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 61/192 (31%), Positives = 98/192 (51%), Gaps = 11/192 (5%) Query: 7 TTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIVRLLI 66 TT GL+ D VIL D RA+ ++VADK +K++ I I AG D + R+ Sbjct: 1 TTIAGLVFRDGVILGADTRATNDSVVADKSCEKIHFIAPKIYCCGAGVAADTEMTTRMAA 60 Query: 67 AEAKLYKMRTGRNIPPLACATLLSNILHSSRMFPFLTQI----IIGGYDLLEGAKLFSLD 122 ++ +L+ + TGR P +A T IL + +F + + ++GG D L G +L+ + Sbjct: 61 SKMELHALSTGRE-PRVATVT---RILRQT-LFRYQGHVGASLVVGGVD-LNGPQLYEVH 114 Query: 123 PLGGMNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERDTFSGNGI 182 P G + FTA GSG A +LE + +M++E +L + A+ + + D SG + Sbjct: 115 PHGSYS-RLPFTALGSGQGAAVALLEDRFQPNMTLEAAQELLVEAITAGILSDLGSGGNV 173 Query: 183 SLAVITKDGVKI 194 VIT G K+ Sbjct: 174 DACVITAGGAKL 185 >6HUB-H nrPDB Length = 234 Score = 80.5 bits (197), Expect = 5e-16, Method: Compositional matrix adjust. Identities = 62/219 (28%), Positives = 103/219 (47%), Gaps = 15/219 (6%) Query: 7 TTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIVRLLI 66 TT G++ D ++L D RA+ G +VADK K++ I I AG+ D +L+ Sbjct: 1 TTIAGVVYKDGIVLGADTRATEGMVVADKNCSKIHFISPNIYCCGAGTAADTDMTTQLIS 60 Query: 67 AEAKLYKMRTGRNIPPLACAT-LLSNILHSSRMFPFLTQIIIGGYDLLEGAKLFSLDPLG 125 + +L+ + TGR +P + A +L +L + + +++GG D + G L+S+ P G Sbjct: 61 SNLELHSLSTGR-LPRVVTANRMLKQMLFRYQGY-IGAALVLGGVD-VTGPHLYSIYPHG 117 Query: 126 GMNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERDTFSGNGISLA 185 ++ + GSGS A V E + DM EE L A+ + + D SG I L Sbjct: 118 S-TDKLPYVTMGSGSLAAMAVFEDKFRPDMEEEEAKNLVSEAIAAGIFNDLGSGGNIDLC 176 Query: 186 VITKDGVKIFEDEEIEKILDSMKAKPKKKTTKRSRRKSK 224 VI+K+ + + P KK T+ R + + Sbjct: 177 VISKNKLDFLRPYTV----------PNKKGTRLGRYRCE 205 >2KU2-A nrPDB Length = 237 Score = 79.7 bits (195), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 62/207 (29%), Positives = 102/207 (49%), Gaps = 9/207 (4%) Query: 3 VMKGTTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIV 62 V KG+T +G+ + V+L +DK+ L+ +K+ IDDY+A +G V DA+ +V Sbjct: 35 VKKGSTALGMKFANGVLLISDKKVR-SRLIEQNSIEKIQLIDDYVAAVTSGLVADARVLV 93 Query: 63 RLLIAEAKLYKMRTGR--NIPPLA--CATLLSNILHSSRMFPFLTQIIIGGYDLLEGAKL 118 A+ K+ G NI L A + + P+ +I G D + G +L Sbjct: 94 DFARISAQQEKVTYGSLVNIENLVKRVADQMQQYTQYGGVRPYGVSLIFAGIDQI-GPRL 152 Query: 119 FSLDPLGGMNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMER-DTF 177 F DP G +NE K TA GSG LE Y ++ +E + L + ALKS++E + Sbjct: 153 FDCDPAGTINEYKA-TAIGSGKDAVVSFLEREYKENLPEKEAVTLGIKALKSSLEEGEEL 211 Query: 178 SGNGISLAVITKDGVKIFEDEEIEKIL 204 I+ ++ + +I++ EE++K L Sbjct: 212 KAPEIA-SITVGNKYRIYDQEEVKKFL 237 >3NZW-L nrPDB Length = 241 Score = 76.3 bits (186), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 55/207 (26%), Positives = 92/207 (44%), Gaps = 19/207 (9%) Query: 5 KGTTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIVRL 64 G T +G+ +D +LA D R + + K++ D I M+ G D A+V+ Sbjct: 27 NGGTILGIAGEDFAVLAGDTRNITDYSINSRYEPKVFDCGDNIVMSANGFAADGDALVKR 86 Query: 65 LIAEAKLYKM-RTGRNIPPLACATLLSNILHSSRMFPFLTQIIIGGYDLLEGAKLFSLDP 123 K Y + + + A + ++L+ R FP+ II G D ++S DP Sbjct: 87 FKNSVKWYHFDHNDKKLSINSAARNIQHLLYGKRFFPYYVHTIIAGLDEDGKGAVYSFDP 146 Query: 124 LGGMNEEKTFTATGSGSPIAYGVL----------EAGYD-------RDMSVEEGIKLALN 166 +G E+ A G+ + + L E G + + +SVEE IKL + Sbjct: 147 VGSYEREQC-RAGGAAASLIMPFLDNQVNFKNQYEPGTNGKVKKPLKYLSVEEVIKLVRD 205 Query: 167 ALKSAMERDTFSGNGISLAVITKDGVK 193 + SA ER G+G+ + ++TKDGV+ Sbjct: 206 SFTSATERHIQVGDGLEILIVTKDGVR 232 >1Q5Q-H nrPDB Length = 235 Score = 75.9 bits (185), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 58/183 (31%), Positives = 92/183 (50%), Gaps = 9/183 (4%) Query: 7 TTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIVRLLI 66 TT V L V+LA D+RA+ GNL+A ++ +K+Y D+Y A IAG+ G A +VRL Sbjct: 1 TTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAGTAGIAIELVRLFA 60 Query: 67 AEAKLYKMRTGRNIPPLACATLLSNILH---SSRMFPFLTQIIIGGYDL-----LEGAKL 118 E + Y+ G + A L++++ + M ++ GYDL ++ Sbjct: 61 VELEHYEKIEGVPLTFDGKANRLASMVRGNLGAAMQGLAVVPLLVGYDLDADDESRAGRI 120 Query: 119 FSLDPLGGMNEEKT-FTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERDTF 177 S D +GG EE+ + A GSGS A L+ Y D E ++ A+ +L A + D+ Sbjct: 121 VSYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDSDEETALRAAIESLYDAADDDSA 180 Query: 178 SGN 180 +G Sbjct: 181 TGG 183 >1Q5R-H nrPDB Length = 294 Score = 75.5 bits (184), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 58/185 (31%), Positives = 92/185 (49%), Gaps = 9/185 (4%) Query: 5 KGTTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIVRL 64 GTT V L V+LA D+RA+ GNL+A ++ + +Y D+Y A IAG+ G A +VRL Sbjct: 64 HGTTIVALTYKGGVLLAGDRRATQGNLIASRDVEAVYVTDEYSAAGIAGTAGIAIELVRL 123 Query: 65 LIAEAKLYKMRTGRNIPPLACATLLSNILH---SSRMFPFLTQIIIGGYDL-----LEGA 116 E + Y+ G + A L++++ + M ++ GYDL Sbjct: 124 FAVELEHYEKIEGVPLTFDGKANRLASMVRGNLGAAMQGLAVVPLLVGYDLDADDESRAG 183 Query: 117 KLFSLDPLGGMNEEKT-FTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERD 175 ++ S D +GG EE+ + A GSGS A L+ Y D E ++ A+ +L A + D Sbjct: 184 RIVSYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDSDEETALRAAIESLYDAADDD 243 Query: 176 TFSGN 180 + +G Sbjct: 244 SATGG 248 >5FMG-C nrPDB Length = 246 Score = 75.5 bits (184), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 71/217 (32%), Positives = 108/217 (49%), Gaps = 23/217 (10%) Query: 3 VMKGTTTVGLICDDAVILATDKRASLGNLVADK--EAKKLYKIDDYIAMTIAGSVGDAQA 60 + + T+GLI D VIL DK + L+ DK +K+YKID +I +AG DA Sbjct: 28 INNASITIGLITKDGVILGADK-VFISKLI-DKANNYEKIYKIDKHIFCGVAGLNADA-- 83 Query: 61 IVRLLIAEAKLYKMRTGRNI----PPLACATLLSNILHSSRMF----PFLTQIIIGGYDL 112 +LI +++LY R N P + +I S + P+ +IGGYD Sbjct: 84 --NILINQSRLYAQRYLYNYNEVQPVSQLVVQICDIKQSYTQYGGLRPYGVSFLIGGYDT 141 Query: 113 LEGAKLFSLDPLGGMNEEKTF-TATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSA 171 +G +L+ DP G N F TA G+ + A VL+ + DM++EEG+ LAL L + Sbjct: 142 KDGYQLYHTDPSG--NYSGWFATAIGTNNLTASSVLKQEWKNDMTLEEGLLLALKTLAKS 199 Query: 172 MERDTFSGNGISLAVIT-KDG---VKIFEDEEIEKIL 204 + + I LA +T KDG K ++EIE+++ Sbjct: 200 TDTEIPKSEKIELAYLTNKDGEVYQKYLTEKEIEELI 236 >5FMG-M nrPDB Length = 240 Score = 73.9 bits (180), Expect = 5e-14, Method: Compositional matrix adjust. Identities = 55/198 (27%), Positives = 92/198 (46%), Gaps = 9/198 (4%) Query: 5 KGTTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIVRL 64 G T +GL D VILA D R SL + + K+ K+ D + +G D + + L Sbjct: 36 NGGTVIGLTGKDYVILAADTRLSLSYSIYTRFCPKISKLTDKCIIGSSGMQSDIKTLHSL 95 Query: 65 LIAEAKLYKMRTGRNIPPLACATLLSNILHSSRMFPFLTQIIIGGYDLLEGAKLFSLDPL 124 L + +L+ + A LL IL+S R FP+ I+ G D L++ D + Sbjct: 96 LQKKIQLFVLEHSHYPDIHVIARLLCVILYSRRFFPYYAFNILAGVDENNKGVLYNYDSV 155 Query: 125 GGMNEEKTFTATGSGSPIAYGVLEAGYDR--------DMSVEEGIKLALNALKSAMERDT 176 G E T + GSGS + +L+ ++ + ++ + I +A+ SA ERD Sbjct: 156 GSYCEA-THSCVGSGSQLILPILDNRVEQKNQLIKNTNFNLGDDINFVKDAITSATERDI 214 Query: 177 FSGNGISLAVITKDGVKI 194 ++G+ + VI K G+ + Sbjct: 215 YTGDKTLIYVIDKMGINV 232 >5FGE-J nrPDB Length = 198 Score = 72.8 bits (177), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 51/193 (26%), Positives = 91/193 (47%), Gaps = 8/193 (4%) Query: 10 VGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIVRLLIAEA 69 +G+ D+VILA+ K + G V K ++ + M+ AG GD + A Sbjct: 5 LGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQANI 64 Query: 70 KLYKMRTGRNIPPLACATL----LSNILHSSRMFPFLTQIIIGGYDLLEG-AKLFSLDPL 124 +LY +R + P A ++ L+ + S R P+ ++IGGYD + +L+ +D L Sbjct: 65 QLYSIREDYELSPQAVSSFVRQELAKSIRSRR--PYQVNVLIGGYDKKKNKPELYQIDYL 122 Query: 125 GGMNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERDTFSGNGISL 184 G E + A G + +L+ Y DM+ EEG+ L ++ +R G+ + Sbjct: 123 -GTKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQELEKRMPMDFKGVIV 181 Query: 185 AVITKDGVKIFED 197 ++ KDG++ +D Sbjct: 182 KIVDKDGIRQVDD 194 >3WXR-K nrPDB Length = 238 Score = 72.4 bits (176), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 54/196 (27%), Positives = 93/196 (47%), Gaps = 14/196 (7%) Query: 10 VGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIVRLLIAEA 69 +G+ D+VILA+ K + G V K ++ + M+ AG GD + A Sbjct: 5 LGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQANI 64 Query: 70 KLYKMRTGRNIPPLACATL----LSNILHSSRMFPFLTQIIIGGYDLLEG-AKLFSLDPL 124 +LY +R + P A ++ L+ + S R P+ ++IGGYD + +L+ +D L Sbjct: 65 QLYSIREDYELSPQAVSSFVRQELAKSIRSRR--PYQVNVLIGGYDKKKNKPELYQIDYL 122 Query: 125 GGMNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEG---IKLALNALKSAMERDTFSGNG 181 G E + A G + +L+ Y DM+ EEG +KL + L+ M D G Sbjct: 123 -GTKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQELEKRMPMDF---KG 178 Query: 182 ISLAVITKDGVKIFED 197 + + ++ KDG++ +D Sbjct: 179 VIVKIVDKDGIRQVDD 194 >5LE5-B nrPDB Length = 261 Score = 72.4 bits (176), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 51/206 (24%), Positives = 103/206 (50%), Gaps = 10/206 (4%) Query: 8 TTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIVRLLIA 67 T +G++ +D V+LA ++R L ++K+YK+++ +A ++AG DA + L Sbjct: 33 TCLGILANDGVLLAAERRNIHKLLDEVFFSEKIYKLNEDMACSVAGITSDANVLTNELRL 92 Query: 68 EAKLYKMRTGRNIPPLACATLLSNILHSSRMF----PFLTQIIIGGYDLLEGAKLFSLDP 123 A+ Y ++ IP T L +I + F PF ++ G+D G +L+ DP Sbjct: 93 IAQRYLLQYQEPIPCEQLVTALCDIKQAYTQFGGKRPFGVSLLYIGWDKHYGFQLYQSDP 152 Query: 124 LGGMNEEKTFTATGSGSPIAYGVLEAGY-DRDMSVEEGIKLALNALKSAMERDTFSGNGI 182 G K T G+ S A +L+ Y + +M+++ + LA+ L M+ S + Sbjct: 153 SGNYGGWKA-TCIGNNSAAAVSMLKQDYKEGEMTLKSALALAIKVLNKTMDVSKLSAEKV 211 Query: 183 SLAVITKDG----VKIFEDEEIEKIL 204 +A +T++ +++ + +E+E+++ Sbjct: 212 EIATLTRENGKTVIRVLKQKEVEQLI 237 >1G0U-D nrPDB Length = 241 Score = 71.2 bits (173), Expect = 3e-13, Method: Compositional matrix adjust. Identities = 56/207 (27%), Positives = 104/207 (50%), Gaps = 5/207 (2%) Query: 6 GTTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIVRLL 65 G+T +G+ + V+L +KRA+ L +D +K+ +ID +I ++G DA++++ Sbjct: 34 GSTAIGIATKEGVVLGVEKRATSPLLESDS-IEKIVEIDRHIGCAMSGLTADARSMIEHA 92 Query: 66 IAEAKLYKMRTGRNIPPLACATLLSNILHSSRMF-PFLTQIIIGGYDLLEGAKLFSLDPL 124 A + + +I + + ++ ++ M PF ++I G+D +G +LF +P Sbjct: 93 RTAAVTHNLYYDEDINVESLTQSVCDLAAAAAMSRPFGVALLIAGHDADDGYQLFHAEPS 152 Query: 125 GGMNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERDTFSGNGISL 184 G A GSGS A L + ++++E L L LK ME + N L Sbjct: 153 GTFYRYNA-KAIGSGSEGAQAELLNEWHSSLTLKEAELLVLKILKQVME-EKLDENNAQL 210 Query: 185 AVITK-DGVKIFEDEEIEKILDSMKAK 210 + ITK DG KI+++E+ +++ +K K Sbjct: 211 SCITKQDGFKIYDNEKTAELIKELKEK 237 >5FMG-H nrPDB Length = 252 Score = 70.5 bits (171), Expect = 6e-13, Method: Compositional matrix adjust. Identities = 58/242 (23%), Positives = 103/242 (42%), Gaps = 54/242 (22%) Query: 7 TTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQ---AIVR 63 TT +G+I D+ V+LA D R S G +++K ++K+ +I++ + + +G+ +Q I++ Sbjct: 1 TTIIGIIYDNGVMLACDSRTSSGTFISNKCSRKINRINENLYVCRSGASAHSQKIIEIIK 60 Query: 64 LLIAEAKLYKMRTGR--------------------------------------------- 78 K + GR Sbjct: 61 HYCVSMKNENRKKGRFHEGETIYDETTYDEEIDIDSINYLDYNNNNDNNLVTKNKYFYED 120 Query: 79 ---NIPPLA--CATLLSNILHSSRMFPFLTQIIIGGYDLLEGAKLFSLDPLGGMNEEKTF 133 + PL A + I++++ F +I GGYD ++ +L++++ G + E+ F Sbjct: 121 KFNDYNPLVENVAHITKKIIYTNNNF-LSCALIFGGYDKIKKQQLYAVNLNGSIIEKHDF 179 Query: 134 TATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERDTFSGNGISLAVITKDGVK 193 +GSGS L+ Y + M+ +E L LN +K AM D SG I + ITK V+ Sbjct: 180 AVSGSGSIYIQSYLQDKYKKFMTKKECFNLILNCVKYAMHNDNSSGGLIRIVNITKSFVE 239 Query: 194 IF 195 F Sbjct: 240 EF 241 >6HE5-A nrPDB Length = 247 Score = 70.1 bits (170), Expect = 7e-13, Method: Compositional matrix adjust. Identities = 55/185 (29%), Positives = 86/185 (46%), Gaps = 14/185 (7%) Query: 3 VMKGTTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIV 62 V +G T +G+ C + VIL DKR L AD +K+YKID++I +G V DA+ ++ Sbjct: 32 VKRGATAIGIKCKEGVILIADKRVGSKLLEADT-IEKIYKIDEHICAATSGLVADARVLI 90 Query: 63 RLLIAEAKLYKMRTGRNIPPLACATLLSNILHSSRMF-------PFLTQIIIGGYDLLEG 115 EA++ ++ P+ L I + + PF ++I G D E Sbjct: 91 DRARIEAQINRLTYDE---PITVKELAKKICDFKQQYTQYGGVRPFGVSLLIAGVD--EV 145 Query: 116 AKLFSLDPLGGMNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERD 175 KL+ DP G + E K TA G G E Y D+S ++ + L L A+ ++E + Sbjct: 146 PKLYETDPSGALLEYKA-TAIGMGRNAVTEFFEKEYRDDLSFDDAMVLGLVAMGLSIESE 204 Query: 176 TFSGN 180 N Sbjct: 205 LVPEN 209 >6EPD-G nrPDB Length = 255 Score = 69.3 bits (168), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 35/127 (27%), Positives = 67/127 (52%), Gaps = 5/127 (3%) Query: 3 VMKGTTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIV 62 V +T +G+ C D V+ +K L L + K+L+ +D ++ M +AG + DA+++ Sbjct: 31 VENSSTAIGIRCKDGVVFGVEKLV-LSKLYEEGSNKRLFNVDRHVGMAVAGLLADARSLA 89 Query: 63 RLLIAEAKLYKMRTGRNIPPLACATLLSNILHSSRMF----PFLTQIIIGGYDLLEGAKL 118 + EA ++ G NIP A ++ +H+ ++ PF ++G Y + +GA+L Sbjct: 90 DIAREEASNFRSNFGYNIPLKHLADRVAMYVHAYTLYSAVRPFGCSFMLGSYSVNDGAQL 149 Query: 119 FSLDPLG 125 + +DP G Sbjct: 150 YMIDPSG 156 >2JAY-A nrPDB Length = 291 Score = 68.2 bits (165), Expect = 3e-12, Method: Compositional matrix adjust. Identities = 54/188 (28%), Positives = 88/188 (46%), Gaps = 15/188 (7%) Query: 5 KGTTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIVRL 64 GTT V L V++A D+R++ GN+++ ++ +K+Y DDY A IAG+ A RL Sbjct: 56 HGTTIVALKYPGGVVMAGDRRSTQGNMISGRDVRKVYITDDYTATGIAGTAAVAVEFARL 115 Query: 65 LIAEAKLYKMRTGRNIPPLACATLLSNI-----------LHSSRMFPFLTQIIIGGYDLL 113 E + Y+ G PL A ++ + + P L I D Sbjct: 116 YAVELEHYEKLEGV---PLTFAGKINRLAIMVRGNLAAAMQGLLALPLLAGYDIHASDPQ 172 Query: 114 EGAKLFSLDPLGGMN-EEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAM 172 ++ S D GG N EE+ + A GSGS A ++ Y + + G+++A+ AL A Sbjct: 173 SAGRIVSFDAAGGWNIEEEGYQAVGSGSLFAKSSMKKLYSQVTDGDSGLRVAVEALYDAA 232 Query: 173 ERDTFSGN 180 + D+ +G Sbjct: 233 DDDSATGG 240 >5FMG-J nrPDB Length = 218 Score = 67.0 bits (162), Expect = 6e-12, Method: Compositional matrix adjust. Identities = 49/201 (24%), Positives = 90/201 (44%), Gaps = 13/201 (6%) Query: 5 KGTTTVGLICDDAVILATDKRASLGNLV-ADKEAKKLYKIDDYIAMTIAGSVGDAQAIVR 63 G +G+ + V +A D R + K++K+++ + + ++G D Q + Sbjct: 8 NGGCVLGMSGSNCVAIACDLRLGANTFTTVSTKFSKIFKMNNNVYVGLSGLATDIQTLYE 67 Query: 64 LLIAEAKLYKMRTGRNIPPLACATLLSNILHSSRMFPFLTQIIIGGYDLL-----EGAKL 118 +L LY++R + A +LS+IL+S+R P+ I+ G+ L EG K Sbjct: 68 ILRYRVNLYEVRQDAEMDVECFANMLSSILYSNRFSPYFVNPIVVGFKLKHYVDEEGEKK 127 Query: 119 FSLDP-------LGGMNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSA 171 + +P +G E + F G S +G+ E+ Y +D + L SA Sbjct: 128 VNYEPYLTAYDLIGAKCETRDFVVNGVTSEQLFGMCESLYVKDQDENGLFETISQCLLSA 187 Query: 172 MERDTFSGNGISLAVITKDGV 192 ++RD SG G + V+T + + Sbjct: 188 LDRDCISGWGAEVLVLTPEKI 208 >5LEZ-C nrPDB Length = 248 Score = 67.0 bits (162), Expect = 6e-12, Method: Compositional matrix adjust. Identities = 60/210 (28%), Positives = 97/210 (46%), Gaps = 14/210 (6%) Query: 3 VMKGTTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIV 62 V KG+T VG+ D V+L +K+ S+ L ++ +K+ +DD + M AG DA+ ++ Sbjct: 26 VKKGSTAVGVRGRDIVVLGVEKK-SVAKLQDERTVRKICALDDNVCMAFAGLTADARIVI 84 Query: 63 RLLIAEAKLYKMRTGRNIP----PLACATLLSNILHSSRMFPFLTQIIIGGYDLLEGAKL 118 E + +++ + A+L S+ PF +I G+D +L Sbjct: 85 NRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSNGRRPFGISALIVGFDFDGTPRL 144 Query: 119 FSLDPLGGMNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEG---IKLALNALKSAMERD 175 + DP G + K A G G+ LE Y D ++E IKL + AL ++ Sbjct: 145 YQTDPSGTYHAWKA-NAIGRGAKSVREFLEKNYT-DEAIETDDLTIKLVIKALLEVVQS- 201 Query: 176 TFSGNGISLAVITKD-GVKIFEDEEIEKIL 204 G I LAV+ +D +KI EEIEK + Sbjct: 202 --GGKNIELAVMRRDQSLKILNPEEIEKYV 229 >5LF3-J nrPDB Length = 201 Score = 65.9 bits (159), Expect = 1e-11, Method: Compositional matrix adjust. Identities = 50/189 (26%), Positives = 91/189 (48%), Gaps = 9/189 (4%) Query: 10 VGLICDDAVILATDKRASLGNLVADKE-AKKLYKIDDYIAMTIAGSVGDAQAIVRLLIAE 68 +G+ D V++A+D+ A+ N+V K+ K++K+ + I + G GD + Sbjct: 5 IGIQGPDYVLVASDRVAA-SNIVQMKDDHDKMFKMSEKILLLCVGEAGDTVQFAEYIQKN 63 Query: 69 AKLYKMRTGRNIPPLACATL----LSNILHSSRMFPFLTQIIIGGYDLLEGAKLFSLDPL 124 +LYKMR G + P A A L++ L S P+ +++ GYD EG L+ +D L Sbjct: 64 VQLYKMRNGYELSPTAAANFTRRNLADCLRSRT--PYHVNLLLAGYDEHEGPALYYMDYL 121 Query: 125 GGMNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERDTFSGNGISL 184 + + A G G+ + +L+ Y +S E ++L L+ +R + S+ Sbjct: 122 AALAKAPF-AAHGYGAFLTLSILDRYYTPTISRERAVELLRKCLEELQKRFILNLPTFSV 180 Query: 185 AVITKDGVK 193 +I K+G+ Sbjct: 181 RIIDKNGIH 189 >2Z5C-C nrPDB Length = 262 Score = 65.9 bits (159), Expect = 1e-11, Method: Compositional matrix adjust. Identities = 57/228 (25%), Positives = 107/228 (46%), Gaps = 20/228 (8%) Query: 6 GTTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIVRLL 65 G+T +G+ + V+L +KRA+ L +D +K+ +ID +I ++G DA++++ Sbjct: 36 GSTAIGIATKEGVVLGVEKRATSPLLESDS-IEKIVEIDRHIGCAMSGLTADARSMIEHA 94 Query: 66 IAEAKLYKMRTGRNIPPLACATLLSNILHSSRMF-------------PFLTQIIIGGYDL 112 A + + +I +L ++ + F PF ++I G+D Sbjct: 95 RTAAVTHNLYYDEDIN---VESLTQSVCDLALRFGEGASGEERLMSRPFGVALLIAGHDA 151 Query: 113 LEGAKLFSLDPLGGMNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAM 172 +G +LF +P G A GSGS A L + ++++E L L LK M Sbjct: 152 DDGYQLFHAEPSGTFYRYNA-KAIGSGSEGAQAELLNEWHSSLTLKEAELLVLKILKQVM 210 Query: 173 ERDTFSGNGISLAVITK-DGVKIFEDEEIEKILDSMKAKPKKKTTKRS 219 E + N L+ ITK DG KI+++E+ +++ +K K ++ + + Sbjct: 211 E-EKLDENNAQLSCITKQDGFKIYDNEKTAELIKELKEKEAAESPEEA 257 >5LZP-A nrPDB Length = 242 Score = 65.1 bits (157), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 52/185 (28%), Positives = 86/185 (46%), Gaps = 15/185 (8%) Query: 8 TTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIVRLLIA 67 T V L V++A D+R++ GN+++ ++ +K+Y DDY A IAG+ A RL Sbjct: 2 TIVALKYPGGVVMAGDRRSTQGNMISGRDVRKVYITDDYTATGIAGTAAVAVEFARLYAV 61 Query: 68 EAKLYKMRTGRNIPPLACATLLSNI-----------LHSSRMFPFLTQIIIGGYDLLEGA 116 E + Y+ G PL A ++ + + P L I D Sbjct: 62 ELEHYEKLEG---VPLTFAGKINRLAIMVRGNLAAAMQGLLALPLLAGYDIHASDPQSAG 118 Query: 117 KLFSLDPLGGMN-EEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERD 175 ++ S D GG N EE+ + A GSGS A ++ Y + + G+++A+ AL A + D Sbjct: 119 RIVSFDAAGGWNIEEEGYQAVGSGSLFAKSSMKKLYSQVTDGDSGLRVAVEALYDAADDD 178 Query: 176 TFSGN 180 + +G Sbjct: 179 SATGG 183 >4FZC-A nrPDB Length = 250 Score = 64.3 bits (155), Expect = 4e-11, Method: Compositional matrix adjust. Identities = 53/190 (27%), Positives = 90/190 (47%), Gaps = 8/190 (4%) Query: 3 VMKGTTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIV 62 V +G T++G+ + V++AT+K++S L + K+ + I +G D + +V Sbjct: 28 VKQGVTSLGIKATNGVVIATEKKSS-SPLAMSETLSKVSLLTPDIGAVYSGMGPDYRVLV 86 Query: 63 RLLIAEAKLYKMRTGRNIPPL-----ACATLLSNILHSSRMFPFLTQIIIGGYDLLEGAK 117 A R PP A ++ S + PF ++I G+D G Sbjct: 87 DKSRKVAHTSYKRIYGEYPPTKLLVSEVAKIMQEATQSGGVRPFGVSLLIAGHDEFNGFS 146 Query: 118 LFSLDPLGGMNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERDTF 177 L+ +DP G K TA G GS A LE ++ ++ +E+ I +AL LK ++E + F Sbjct: 147 LYQVDPSGSYFPWKA-TAIGKGSVAAKTFLEKRWNDELELEDAIHIALLTLKESVEGE-F 204 Query: 178 SGNGISLAVI 187 +G+ I LA+I Sbjct: 205 NGDTIELAII 214 >5GJR-F nrPDB Length = 241 Score = 62.8 bits (151), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 57/216 (26%), Positives = 99/216 (45%), Gaps = 28/216 (12%) Query: 6 GTTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIVRLL 65 G+T +G+ + V LA +KR + L+ +K+ +ID +I ++G + DA+ ++ Sbjct: 34 GSTAIGIQTSEGVCLAVEKRIT-SPLMEPSSIEKIVEIDAHIGCAMSGLIADAKTLIDKA 92 Query: 66 IAEAKLYKMRTGRNIPPLACATLLSNILHS-----------SRMFPFLTQIIIGGYDLLE 114 E + + + + +SN+ SR PF ++ GG D + Sbjct: 93 RVETQNHWFTYNETMTVESVTQAVSNLALQFGEEDADPGAMSR--PFGVALLFGGVD-EK 149 Query: 115 GAKLFSLDPLGGMNEEKTFT-----ATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALK 169 G +LF +DP G TF A GS S A L+ Y + M+++E IK +L LK Sbjct: 150 GPQLFHMDPSG------TFVQCDARAIGSASEGAQSSLQEVYHKSMTLKEAIKSSLIILK 203 Query: 170 SAMERDTFSGNGISLAVITK-DGVKIFEDEEIEKIL 204 ME + + I LA + +F EE+E+++ Sbjct: 204 QVME-EKLNATNIELATVQPGQNFHMFTKEELEEVI 238 >6FVW-g nrPDB Length = 245 Score = 59.3 bits (142), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 54/178 (30%), Positives = 78/178 (43%), Gaps = 10/178 (5%) Query: 3 VMKGTTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIV 62 V GTT++G+ C+D V+ A +K + LV K K+ +D +I +G + D + +V Sbjct: 28 VENGTTSIGIKCNDGVVFAVEKLITSKLLVPQKNV-KIQVVDRHIGCVYSGLIPDGRHLV 86 Query: 63 RLLIAEAKLYKMRTGRNIPPLACATLLSNILHSSRMF----PFLTQIIIGGYDLLEGAKL 118 EA +K IP A A L + + ++ PF I GG D GA L Sbjct: 87 NRGREEAASFKKLYKTPIPIPAFADRLGQYVQAHTLYNSVRPFGVSTIFGGVD-KNGAHL 145 Query: 119 FSLDPLGGMNEEKTFTATGSGSPIAYGVLEAGYDRD---MSVEEGIKLALNALKSAME 173 + L+P G K ATG G A LE D +S E +K A + A E Sbjct: 146 YMLEPSGSYWGYKG-AATGKGRQSAKAELEKLVDHHPEGLSAREAVKQAAKIIYLAHE 202 >5FGG-F nrPDB Length = 288 Score = 58.5 bits (140), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 54/178 (30%), Positives = 78/178 (43%), Gaps = 10/178 (5%) Query: 3 VMKGTTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIV 62 V GTT++G+ C+D V+ A +K + LV K K+ +D +I +G + D + +V Sbjct: 31 VENGTTSIGIKCNDGVVFAVEKLITSKLLVPQKNV-KIQVVDRHIGCVYSGLIPDGRHLV 89 Query: 63 RLLIAEAKLYKMRTGRNIPPLACATLLSNILHSSRMF----PFLTQIIIGGYDLLEGAKL 118 EA +K IP A A L + + ++ PF I GG D GA L Sbjct: 90 NRGREEAASFKKLYKTPIPIPAFADRLGQYVQAHTLYNSVRPFGVSTIFGGVD-KNGAHL 148 Query: 119 FSLDPLGGMNEEKTFTATGSGSPIAYGVLEAGYDRD---MSVEEGIKLALNALKSAME 173 + L+P G K ATG G A LE D +S E +K A + A E Sbjct: 149 YMLEPSGSYWGYKG-AATGKGRQSAKAELEKLVDHHPEGLSAREAVKQAAKIIYLAHE 205 >5T0I-L nrPDB Length = 268 Score = 58.2 bits (139), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 58/224 (25%), Positives = 108/224 (48%), Gaps = 21/224 (9%) Query: 3 VMKGTTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIV 62 V +G+ TVGL +L KRA L A + KK+ +D++I ++IAG DA+ + Sbjct: 34 VKQGSATVGLKSKTHAVLVALKRAQ-SELAAHQ--KKILHVDNHIGISIAGLTADARLLC 90 Query: 63 RLLIAEAKLYKMRTGRNIPPLACATLLSNILHSSRM-------FPFLTQIIIGGYDLLEG 115 + E + R PL + L+S I +++ P+ ++I GYD + G Sbjct: 91 NFMRQECLDSRFVFDR---PLPVSRLVSLIGSKTQIPTQRYGRRPYGVGLLIAGYDDM-G 146 Query: 116 AKLFSLDPLGGMNEEKTFTATGSGSPIAYGVLEAGYDRDM--SVEEGIKLALNALKSAM- 172 +F P + + + G+ S A LE M ++ E +K L AL+ + Sbjct: 147 PHIFQTCPSANYFDCRAMS-IGARSQSARTYLERHMSEFMECNLNELVKHGLRALRETLP 205 Query: 173 -ERDTFSGNGISLAVITKD-GVKIFEDEEIEKILDSMKAKPKKK 214 E+D + N +S+ ++ KD I++D+++ L+ ++ +P++K Sbjct: 206 AEQDLTTKN-VSIGIVGKDLEFTIYDDDDVSPFLEGLEERPQRK 248 >5FMG-D nrPDB Length = 241 Score = 57.0 bits (136), Expect = 6e-09, Method: Compositional matrix adjust. Identities = 49/207 (23%), Positives = 92/207 (44%), Gaps = 9/207 (4%) Query: 3 VMKGTTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIV 62 V KG V + + +LA +K+ ++ L K +KL K+D++ + AG DA+ +V Sbjct: 26 VKKGGCAVAIKSSNFAVLAVEKK-NIPKLQNPKTTEKLIKLDEHNCLAFAGLNADARVLV 84 Query: 63 RLLIAEAKLYKMRTGRNIPPLACATLLSNI----LHSSRMFPFLTQIIIGGYDLLEGAKL 118 E + Y + P A ++ + H + PF +I G+ + + Sbjct: 85 NKTRLECQRYYLNMDEPAPVDYIAKYVAKVQQKFTHRGGVRPFGIATLIAGFKNNKEICI 144 Query: 119 FSLDPLGGMNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERDTFS 178 + +P G K A G + I LE Y +M ++ I LAL A+ +E S Sbjct: 145 YQTEPSGIYAAWKA-QAIGKNAKIVQEFLEKNYQENMEQKDCIFLALKAIFEVVE---LS 200 Query: 179 GNGISLAVITKDGVKIFEDEEIEKILD 205 + +A++T+ + E++EI +++ Sbjct: 201 SKNVEVALLTEKDLTFIEEQEINSMVE 227 >6EPE-7 nrPDB Length = 263 Score = 57.0 bits (136), Expect = 7e-09, Method: Compositional matrix adjust. Identities = 52/201 (25%), Positives = 98/201 (48%), Gaps = 15/201 (7%) Query: 3 VMKGTTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIV 62 ++ GT+ +G+ D V++A D S G+L + ++ +++D + +G D Q + Sbjct: 49 MVTGTSVLGVKFDCGVVIAADMLGSYGSLARFRNISRIMRVNDSTMLGASGDYADFQYLK 108 Query: 63 RLL---IAEAKLYKMRTGRNIPPLACATLLSNILHS--SRMFPFLTQIIIGGYDLLEGAK 117 ++L + + +L+ G + P A + L+ ++S S+M P +IGGY G + Sbjct: 109 QVLGQMVIDEELFG--DGHSYSPRAIHSWLTRAMYSRRSKMNPLWNTKVIGGY---AGGE 163 Query: 118 LF--SLDPLGGMNEEKTFTATGSGSPIAYGVLEAGYDRD--MSVEEGIKLALNALKSAME 173 F +D LG E + ATG G+ +A +L ++ +S E +L ++ Sbjct: 164 SFLGYVDMLGVAYEAPSL-ATGYGAYLAQPLLREVLEKQPVLSQTEARELVERCMRVLYY 222 Query: 174 RDTFSGNGISLAVITKDGVKI 194 RD S N +A +T+ GV+I Sbjct: 223 RDARSYNRFQVATVTEKGVEI 243 >6GOP-M nrPDB Length = 246 Score = 56.2 bits (134), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 55/217 (25%), Positives = 96/217 (44%), Gaps = 20/217 (9%) Query: 3 VMKGTTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIV 62 ++ GT+ + + D+ VI+A D S G+L+ ++L + D + I+G + D Q I Sbjct: 18 IVTGTSVISMKYDNGVIIAADNLGSYGSLLRFNGVERLIPVGDNTVVGISGDISDMQHIE 77 Query: 63 RLL--IAEAKLYKMRTG---RNIPPLACATLLSNILHS--SRMFPFLTQIIIGGYDLLEG 115 RLL + Y + P L+ +++ S+M P II+ G G Sbjct: 78 RLLKDLVTENAYDNPLADAEEALEPSYIFEYLATVMYQRRSKMNPLWNAIIVAGVQ-SNG 136 Query: 116 AKLFSLDPLGGMNEEKTFTATGSGSPIAYGVLEAGYDRDMSV--------EEGIKLALNA 167 + L G+ ATG G+ +A +L DR+ + EE I +NA Sbjct: 137 DQFLRYVNLLGVTYSSPTLATGFGAHMANPLLRKVVDRESDIPKTTVQVAEEAI---VNA 193 Query: 168 LKSAMERDTFSGNGISLAVITKD-GVKIFEDEEIEKI 203 ++ RD S SLA+I K+ G+ ++ ++E + Sbjct: 194 MRVLYYRDARSSRNFSLAIIDKNTGLTFKKNLQVENM 230 >5LF6-M nrPDB Length = 219 Score = 56.2 bits (134), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 47/199 (23%), Positives = 95/199 (47%), Gaps = 11/199 (5%) Query: 3 VMKGTTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIV 62 ++ GT+ +G+ + V++A D S G+L + ++ ++++ + +G D Q + Sbjct: 5 MVTGTSVLGVKFEGGVVIAADMLGSYGSLARFRNISRIMRVNNSTMLGASGDYADFQYLK 64 Query: 63 RLL---IAEAKLYKMRTGRNIPPLACATLLSNILHS--SRMFPFLTQIIIGGYDLLEGAK 117 ++L + + +L + G + P A + L+ ++S S+M P ++IGGY +G Sbjct: 65 QVLGQMVIDEEL--LGDGHSYSPRAIHSWLTRAMYSRRSKMNPLWNTMVIGGY--ADGES 120 Query: 118 LFSLDPLGGMNEEKTFTATGSGSPIAYGVLEAGYDRD--MSVEEGIKLALNALKSAMERD 175 + G+ E ATG G+ +A +L ++ +S E L ++ RD Sbjct: 121 FLGYVDMLGVAYEAPSLATGYGAYLAQPLLREVLEKQPVLSQTEARDLVERCMRVLYYRD 180 Query: 176 TFSGNGISLAVITKDGVKI 194 S N +A +T+ GV+I Sbjct: 181 ARSYNRFQIATVTEKGVEI 199 >5GJQ-g nrPDB Length = 264 Score = 55.5 bits (132), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 47/199 (23%), Positives = 95/199 (47%), Gaps = 11/199 (5%) Query: 3 VMKGTTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIV 62 ++ GT+ +G+ + V++A D S G+L + ++ ++++ + +G D Q + Sbjct: 50 MVTGTSVLGVKFEGGVVIAADMLGSYGSLARFRNISRIMRVNNSTMLGASGDYADFQYLK 109 Query: 63 RLL---IAEAKLYKMRTGRNIPPLACATLLSNILHS--SRMFPFLTQIIIGGYDLLEGAK 117 ++L + + +L + G + P A + L+ ++S S+M P ++IGGY +G Sbjct: 110 QVLGQMVIDEEL--LGDGHSYSPRAIHSWLTRAMYSRRSKMNPLWNTMVIGGY--ADGES 165 Query: 118 LFSLDPLGGMNEEKTFTATGSGSPIAYGVLEAGYDRD--MSVEEGIKLALNALKSAMERD 175 + G+ E ATG G+ +A +L ++ +S E L ++ RD Sbjct: 166 FLGYVDMLGVAYEAPSLATGYGAYLAQPLLREVLEKQPVLSQTEARDLVERCMRVLYYRD 225 Query: 176 TFSGNGISLAVITKDGVKI 194 S N +A +T+ GV+I Sbjct: 226 ARSYNRFQIATVTEKGVEI 244 >5FMG-N nrPDB Length = 265 Score = 51.6 bits (122), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 59/247 (23%), Positives = 98/247 (39%), Gaps = 47/247 (19%) Query: 3 VMKGTTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIV 62 V+ GT+ + + +++A D++AS G+ + ++++KI++ M +G + DAQ + Sbjct: 6 VVTGTSVIAIKYKHGIMIAADRKASYGSYAKFQNVERIFKINNKTVMGFSGELADAQYLH 65 Query: 63 RLL-------IAEAKLYKMRTGRNIPPLACATLLSNILH--SSRMFPFLTQIIIGG---- 109 LL ++E K R P + +S + + +R+ P III G Sbjct: 66 ELLTRKNINNLSEKK----RKEDMYTPQHYHSYVSRVFYVRKNRIDPLFNNIIIAGINSQ 121 Query: 110 -YD------LL----------------EGAKLFSLDPL-------GGMNEEKTFTATGSG 139 YD LL E K D L G N + TG Sbjct: 122 KYDNNDDNVLLYTNKNNDDEQNEYKNNEEYKEIHKDDLYIGFVDMHGTNFCDDYITTGYA 181 Query: 140 SPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERDTFSGNGISLAVITKDGVKIFEDEE 199 A +L Y +M+ EE L L+ RD S N I + +T GV+ E Sbjct: 182 RYFALTLLRDHYKDNMTEEEARILINECLRILYFRDATSSNFIQIVKVTSKGVEYEEPYI 241 Query: 200 IEKILDS 206 + +L+S Sbjct: 242 LPCVLNS 248 >5LF0-A nrPDB Length = 234 Score = 51.2 bits (121), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 52/210 (24%), Positives = 90/210 (42%), Gaps = 10/210 (4%) Query: 3 VMKGTTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIV 62 V G +VG+ + V+LAT+K+ L ++ K+ I +I + +G D + +V Sbjct: 29 VAGGAPSVGIKAANGVVLATEKKQK-SILYDERSVHKVEPITKHIGLVYSGMGPDYRVLV 87 Query: 63 RLLIAEAKLYKMRTGRNIPPLA----CATLLSNILHSSRMFPFLTQIIIGGYDLLEG-AK 117 A+ Y + IP A+++ S + PF ++I G++ EG Sbjct: 88 HRARKLAQQYYLVYQEPIPTAQLVQRVASVMQEYTQSGGVRPFGVSLLICGWN--EGRPY 145 Query: 118 LFSLDPLGGMNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERDTF 177 LF DP G K TA G LE Y+ D+ +E+ I A+ LK + E Sbjct: 146 LFQSDPSGAYFAWKA-TAMGKNYVNGKTFLEKRYNEDLELEDAIHTAILTLKESFEGQMT 204 Query: 178 SGNGISLAVITKDGVKIFEDEEIEKILDSM 207 N I + + + G + E++ L ++ Sbjct: 205 EDN-IEVGICNEAGFRRLTPTEVKDYLAAI 233 >1IRU-A nrPDB Length = 246 Score = 48.9 bits (115), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 51/207 (24%), Positives = 93/207 (44%), Gaps = 11/207 (5%) Query: 6 GTTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIVRLL 65 G T+V + D ++ T K+ L+ L+KI + I + G D+++ V+ Sbjct: 36 GLTSVAVRGKDCAVIVTQKKVP-DKLLDSSTVTHLFKITENIGCVMTGMTADSRSQVQRA 94 Query: 66 IAEAKLYKMRTGRNIP-PLACATL--LSNIL-HSSRMFPFLTQIIIGGYDLLEGAKLFSL 121 EA +K + G IP + C + +S + ++ M P +I+ G D +G +++ Sbjct: 95 RYEAANWKYKYGYEIPVDMLCKRIADISQVYTQNAEMRPLGCCMILIGIDEEQGPQVYKC 154 Query: 122 DPLGGMNEEKTFTATGSGSPIAYGVLEAGYDR--DMSVEEGIKLALNALKSAMERDTFSG 179 DP G K TA G + LE + D + E+ ++ A+ L + + D F Sbjct: 155 DPAGYYCGFKA-TAAGVKQTESTSFLEKKVKKKFDWTFEQTVETAITCLSTVLSID-FKP 212 Query: 180 NGISLAVITKDGVK--IFEDEEIEKIL 204 + I + V+T + K I + EI+ L Sbjct: 213 SEIEVGVVTVENPKFRILTEAEIDAHL 239 >5FMG-G nrPDB Length = 252 Score = 48.9 bits (115), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 28/129 (21%), Positives = 56/129 (43%), Gaps = 5/129 (3%) Query: 3 VMKGTTTVGLICDDAVILAT-DKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAI 61 + T + L C D +I + ++ ++Y +++ I +T +G GDA+ I Sbjct: 31 INNNNTALCLECKDGIICCCINSNMDKNKMIKKNSYNRIYHVNNNIIITYSGFDGDARNI 90 Query: 62 VRLLIAEAKLYKMRTGRNIPPLACATLLSNILHSSRMF----PFLTQIIIGGYDLLEGAK 117 + +EA Y NIP +S +H+ ++ PF III ++ + Sbjct: 91 IDRARSEANTYYYNFHTNIPLHILVNRISLYIHAYTLYWHMRPFAASIIISSFNEKDKGD 150 Query: 118 LFSLDPLGG 126 ++ ++P G Sbjct: 151 IYCIEPNGA 159 >4YA5-C nrPDB Length = 254 Score = 48.1 bits (113), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 48/214 (22%), Positives = 91/214 (42%), Gaps = 13/214 (6%) Query: 3 VMKGTTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIV 62 V +GT VG+ + V+L ++R++L K+ KID ++ ++ +G D++ ++ Sbjct: 27 VKRGTCAVGVKGKNCVVLGCERRSTLKLQDTRITPSKVSKIDSHVVLSFSGLNADSRILI 86 Query: 63 RLLIAEAKLYKMRTGRNIP----PLACATLLSNILHSSRMFPFLTQIIIGGYDLLEG-AK 117 EA+ +++ + A + S + PF +I G+D + K Sbjct: 87 EKARVEAQSHRLTLEDPVTVEYLTRYVAGVQQRYTQSGGVRPFGVSTLIAGFDPRDDEPK 146 Query: 118 LFSLDPLGGMNEEKTFTATGSGSPIAYGVLEAGYDR---DMSVEEGIKLALNALKSAMER 174 L+ +P G+ + G S LE YDR +VEE +KL + +L +E Sbjct: 147 LYQTEP-SGIYSSWSAQTIGRNSKTVREFLEKNYDRKEPPATVEECVKLTVRSL---LEV 202 Query: 175 DTFSGNGISLAVITKDG-VKIFEDEEIEKILDSM 207 I + V+ D + EEI + + + Sbjct: 203 VQTGAKNIEITVVKPDSDIVALSSEEINQYVTQI 236 >3NZW-E nrPDB Length = 234 Score = 47.8 bits (112), Expect = 4e-06, Method: Compositional matrix adjust. Identities = 53/214 (24%), Positives = 97/214 (45%), Gaps = 20/214 (9%) Query: 3 VMKGTTTVGLICDDAVILATDKRASLGNLVADKEA---KKLYKIDDYIAMTIAGSVGDAQ 59 + +G+ TVGL + +L KR AD+ + KK+ K D+++ +++AG DA+ Sbjct: 29 IKQGSVTVGLRSNTHAVLVALKRN------ADELSSYQKKIIKCDEHMGLSLAGLAPDAR 82 Query: 60 AIVRLLIAEAKLYKMRTGRNIPPLACATLLSNILHSSRMF----PFLTQIIIGGYDLLEG 115 + L + + R + LL + + P+ ++I GYD G Sbjct: 83 VLSNYLRQQCNYSSLVFNRKLAVERAGHLLCDKAQKNTQSYGGRPYGVGLLIIGYD-KSG 141 Query: 116 AKLFSLDPLGGMNEEKTFTATGSGSPIAYGVLEAGYDR----DMSVEEGIKLALNALKSA 171 A L P G + E TA G+ S A LE D D + +E IK + A+ + Sbjct: 142 AHLLEFQPSGNVTELYG-TAIGARSQGAKTYLERTLDTFIKIDGNPDELIKAGVEAISQS 200 Query: 172 MERDTFSGNGISLAVITKDG-VKIFEDEEIEKIL 204 + ++ + + +S+A++ KD I++ E + K + Sbjct: 201 LRDESLTVDNLSIAIVGKDTPFTIYDGEAVAKYI 234 >5FMG-F nrPDB Length = 254 Score = 39.7 bits (91), Expect = 0.001, Method: Compositional matrix adjust. Identities = 48/196 (24%), Positives = 89/196 (45%), Gaps = 15/196 (7%) Query: 3 VMKGTTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIV 62 + +GT V + D V+++ K+ + L +E K++KIDDYI ++++G DA+ + Sbjct: 29 IKQGTCAVAIKSKDYVVVSGLKKC-ISKLSFPQE--KIFKIDDYIGISMSGITSDAKVLT 85 Query: 63 RLLIAEAKLYKMRTGRNIPPLACATLLS-----NILHSSRMFPFLTQIIIGGYDLLEGAK 117 + + E +K NI + ++ N SS+ F ++I Y Sbjct: 86 KFMQNECLSHKFLYNENINIESLVRSVADKYQKNTQKSSKR-AFGVGLMIAAYH--NEPC 142 Query: 118 LFSLDPLGGMNEEKTFTATGSGSPIAYGVLEAGYD--RDMSVEEGIKLALNALKSAMERD 175 +F P G E + G+ S + LE + S+EE I L ALK ++ + Sbjct: 143 IFETRPNGSYFEYDALS-FGARSHASKTYLEKNLHLFEECSLEELILHCLKALKCSLSSE 201 Query: 176 T-FSGNGISLAVITKD 190 + + + +LAV+ K+ Sbjct: 202 SELTISNTALAVVGKN 217 >5LOY-A nrPDB Length = 240 Score = 39.3 bits (90), Expect = 0.001, Method: Compositional matrix adjust. Identities = 48/203 (23%), Positives = 84/203 (41%), Gaps = 15/203 (7%) Query: 7 TTTVGLICDDAVILATDKRASLG-NLVADKEAKKLYKI--DDYIAMTIAGSVGDAQAIVR 63 T VG+ D+ ++ A+D R + G + ++ ++++ + I + AG++ QA++ Sbjct: 1 TYCVGIRLDEGLVFASDSRTNAGVDNISTFRKMHVFEVPGERVIVLLTAGNLATTQAVIS 60 Query: 64 LLIAEAKLYKMRTGRNIPPLACATLLSNILH--SSRMFP--------FLTQIIIGGYDLL 113 LL K + R A L+ L +R P F I+GG Sbjct: 61 LLEERLKDPEERLLTAPSMFEAARLVGEALREVQARDAPALEADGVDFNASFILGGQIAG 120 Query: 114 EGAKLFSLDPLGGMNEEKTFTATGSGSPIAYG--VLEAGYDRDMSVEEGIKLALNALKSA 171 E +LF + P G E T YG +L+ D S+E+ K AL + S Sbjct: 121 EPPRLFLIYPAGNFIEATPDTPFFQIGETKYGKPILDRVITPDTSLEDAAKCALVSFDST 180 Query: 172 MERDTFSGNGISLAVITKDGVKI 194 M + G + L V +D +++ Sbjct: 181 MRSNLSVGLPLDLLVYERDSLRV 203 >4HO7-A nrPDB Length = 179 Score = 34.7 bits (78), Expect = 0.038, Method: Compositional matrix adjust. Identities = 47/189 (24%), Positives = 78/189 (41%), Gaps = 25/189 (13%) Query: 7 TTTVGLICDDAVILATDKRASLGN-LVADKEAKKLYKIDDYIAMTIAGSVGDAQAIVRLL 65 TT + + D V+L D++ +LG +VA A KL +I+D + + AGS DA +++ L Sbjct: 1 TTILSVRKGDTVVLLGDRQVTLGERIVAKSSACKLRRINDDVVIGFAGSTADAISLMEKL 60 Query: 66 IAEAKLYKMRTGRNIPPLACATLLSNILHSSRMFPFLTQIIIGGYDLLEGAKLFSLDPLG 125 + + + R A L+ + R L +I + + +D G Sbjct: 61 ENKIGEFPNQLTR------AAVELAKEWRTDRALRRLEASLI----VCSAEETLEIDGQG 110 Query: 126 GM--NEEKTFTATGSGSPIAYGVLEA-----GYDRDMSVEEGIKLALNALKSAMERDTFS 178 + E A GSG A A GYD + K+A A++ A + D FS Sbjct: 111 NVITPEADGIVAIGSGGTFAKAAARALIDVDGYDAE-------KIARKAMRIATDIDVFS 163 Query: 179 GNGISLAVI 187 + V+ Sbjct: 164 NEHWDVEVL 172 >5L5W-G nrPDB Length = 252 Score = 32.7 bits (73), Expect = 0.14, Method: Compositional matrix adjust. Identities = 42/176 (23%), Positives = 75/176 (42%), Gaps = 13/176 (7%) Query: 40 LYKIDDYIAMTIAGSVGDAQAIVRLLIAEAKLYKMRTGRNIPPLACATLLSNI--LHSSR 97 ++ I I M + G + DA+ AEA ++ + G ++P A ++N+ +++ R Sbjct: 72 IFCISRTIGMVVNGPIPDARNAALRAKAEAAEFRYKYGYDMPCDVLAKRMANLSQIYTQR 131 Query: 98 MF--PFLTQIIIGGYDLLEGAKLFSLDPLGGMNEEKTFTATGSGSPIAYGVLEAGYDR-- 153 + P + D G ++ DP G K TATG LE + + Sbjct: 132 AYMRPLGVILTFVSVDEELGPSIYKTDPAGYYVGYKA-TATGPKQQEITTNLENHFKKSK 190 Query: 154 -----DMSVEEGIKLALNALKSAMERDTFSGNGISLAVITKDGVKIFEDEEIEKIL 204 + S E+ ++ A+ + A+ + FS N + + V TKD E IE+ L Sbjct: 191 IDHINEESWEKVVEFAITHMIDALGTE-FSKNDLEVGVATKDKFFTLSAENIEERL 245 >5FMG-A nrPDB Length = 260 Score = 32.0 bits (71), Expect = 0.25, Method: Compositional matrix adjust. Identities = 32/131 (24%), Positives = 54/131 (41%), Gaps = 17/131 (12%) Query: 8 TTVGLICDDAVILATDKRASLGNLVADK-----EAKKLYKIDDYIAMTIAGSVGDAQAIV 62 T+VG+ ++ ++ + K+ + + DK +Y I D I ++ G GD ++V Sbjct: 38 TSVGVKGENCAVIISQKKMATQYISQDKLLDYNNITNIYNITDEIGCSMVGMPGDCLSMV 97 Query: 63 RLLIAEAKLYKMRTGRNIPPLACATLLSNIL--------HSSRMFPFLTQIIIGGYDLLE 114 +EA + G N+ TL NI H+ + +II G D Sbjct: 98 YKARSEASEFLYSNGYNVNA---ETLCRNICDKIQVYTQHAYMRLHACSGMII-GIDENN 153 Query: 115 GAKLFSLDPLG 125 +LF DP G Sbjct: 154 KPELFKFDPSG 164 >5JI2-A nrPDB Length = 184 Score = 31.2 bits (69), Expect = 0.39, Method: Compositional matrix adjust. Identities = 40/138 (28%), Positives = 60/138 (43%), Gaps = 10/138 (7%) Query: 7 TTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKI-DDYIAMTIAGSVGDAQAIVRLL 65 TT V + + V++A D +A+LGN V KK+ ++ +D + AG DA + L Sbjct: 2 TTIVSVRRNGHVVIAGDGQATLGNTVMKGNVKKVRRLYNDKVIAGFAGGTADAFTLFELF 61 Query: 66 IAEAKLYKMRTGRNIPPLACATLLSNILHSSRMFPFLTQIIIGGYDLLEGAKLFSLDPLG 125 E KL +M G + A L+ + RM L + ++ D E A L Sbjct: 62 --ERKL-EMHQGHLVK---AAVELAKDWRTDRMLRKL-EALLAVAD--ETASLIITGNGD 112 Query: 126 GMNEEKTFTATGSGSPIA 143 + E A GSG P A Sbjct: 113 VVQPENDLIAIGSGGPYA 130 >4GBJ-A nrPDB Length = 297 Score = 30.0 bits (66), Expect = 0.78, Method: Compositional matrix adjust. Identities = 28/86 (32%), Positives = 46/86 (53%), Gaps = 11/86 (12%) Query: 127 MNEEKTFTATGS-GSPIAYGVLEAGY-----DRDMSVEEGI-KLALNALKSAMERDTFSG 179 M+E+ F G+ G+PIA +LEAGY +R S E + KL +++A+ D + Sbjct: 4 MSEKIAFLGLGNLGTPIAEILLEAGYELVVWNRTASKAEPLTKLGATVVENAI--DAITP 61 Query: 180 NGISLAVITKDGV--KIFEDEEIEKI 203 GI +V+ D ++F E +EK+ Sbjct: 62 GGIVFSVLADDAAVEELFSMELVEKL 87 >2D6F-A nrPDB Length = 435 Score = 29.6 bits (65), Expect = 1.2, Method: Compositional matrix adjust. Identities = 14/25 (56%), Positives = 18/25 (72%), Gaps = 1/25 (4%) Query: 174 RDTF-SGNGISLAVITKDGVKIFED 197 RDTF S N + LA +T DG+KI E+ Sbjct: 260 RDTFRSMNALPLAEVTPDGIKILEE 284 >4CQD-A nrPDB Length = 423 Score = 29.6 bits (65), Expect = 1.2, Method: Compositional matrix adjust. Identities = 15/45 (33%), Positives = 25/45 (55%), Gaps = 3/45 (6%) Query: 130 EKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMER 174 +K+FT+TG P + Y RD ++E+G+K NA ++R Sbjct: 84 DKSFTSTGERLPKFWS---RPYTRDAAIEDGLKYYKNATHEEIKR 125 >5CW8-A nrPDB Length = 203 Score = 27.7 bits (60), Expect = 3.7, Method: Compositional matrix adjust. Identities = 13/43 (30%), Positives = 24/43 (55%) Query: 168 LKSAMERDTFSGNGISLAVITKDGVKIFEDEEIEKILDSMKAK 210 L AM+R+ ++ A + D E +++EK++DSM A+ Sbjct: 104 LNRAMQRNPLLTEAMTRAYVFADASAASEVDQVEKLIDSMFAR 146 >3UW2-A nrPDB Length = 485 Score = 27.7 bits (60), Expect = 4.5, Method: Compositional matrix adjust. Identities = 11/24 (45%), Positives = 16/24 (66%) Query: 177 FSGNGISLAVITKDGVKIFEDEEI 200 F G+G L V+TKDG I+ D ++ Sbjct: 263 FDGDGDRLGVVTKDGQIIYPDRQL 286 >4P9S-A nrPDB Length = 848 Score = 26.9 bits (58), Expect = 7.7, Method: Composition-based stats. Identities = 20/63 (31%), Positives = 32/63 (50%), Gaps = 1/63 (1%) Query: 139 GSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERDTFSGNGISLAVITKDGVKIFEDE 198 G +AY + +AG RD+ + E +L + A T+ GI+L I D +K++E Sbjct: 35 GVSLAYHLAKAGM-RDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKIHYDSIKLYERL 93 Query: 199 EIE 201 E E Sbjct: 94 EEE 96 >5B2N-A nrPDB Length = 279 Score = 26.6 bits (57), Expect = 8.6, Method: Compositional matrix adjust. Identities = 13/37 (35%), Positives = 21/37 (56%) Query: 39 KLYKIDDYIAMTIAGSVGDAQAIVRLLIAEAKLYKMR 75 +LY++DD + I G+V A +V I K++K R Sbjct: 150 QLYEVDDIAQLMIWGAVSTAFFVVMNWIVGTKIFKNR 186 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 3H4P-a nrPDB 273 3e-74 3NZW-K nrPDB 233 4e-62 6EPF-5 nrPDB 229 1e-60 5L5A-K nrPDB 227 2e-60 5CZ8-K nrPDB 225 1e-59 5L64-K nrPDB 225 1e-59 5LN3-5 nrPDB 224 3e-59 6AVO-C nrPDB 222 1e-58 6EPC-1 nrPDB 217 3e-57 3UNF-K nrPDB 216 5e-57 6EPF-2 nrPDB 215 9e-57 6HEC-1 nrPDB 214 2e-56 5GJQ-a nrPDB 213 5e-56 5L4G-8 nrPDB 211 2e-55 3UNB-K nrPDB 210 3e-55 6HUB-H nrPDB 207 4e-54 5FMG-L nrPDB 204 2e-53 5LEZ-N nrPDB 203 6e-53 3IPM-H nrPDB 199 6e-52 5FMG-I nrPDB 199 8e-52 2Z5C-C nrPDB 198 1e-51 1G0U-D nrPDB 197 3e-51 6AVO-A nrPDB 193 4e-50 5MPC-h nrPDB 192 1e-49 3UNH-H nrPDB 191 2e-49 3H4P-A nrPDB 191 3e-49 6AVO-B nrPDB 190 4e-49 5FMG-E nrPDB 189 1e-48 5FGI-H nrPDB 188 2e-48 3UNF-N nrPDB 184 2e-47 6J30-C nrPDB 184 3e-47 6HV7-H nrPDB 183 4e-47 6HE5-A nrPDB 183 6e-47 5GJR-F nrPDB 183 6e-47 5FMG-D nrPDB 180 5e-46 5LE5-B nrPDB 178 1e-45 5T0I-L nrPDB 177 5e-45 4YA5-C nrPDB 177 5e-45 5L4G-U nrPDB 176 8e-45 5LF0-A nrPDB 175 1e-44 5VFT-S nrPDB 175 2e-44 5LEZ-C nrPDB 174 2e-44 3UNE-I nrPDB 174 3e-44 5FMG-M nrPDB 173 5e-44 4FZC-A nrPDB 172 2e-43 5FMG-C nrPDB 171 2e-43 6EPF-6 nrPDB 170 7e-43 2KU2-A nrPDB 169 1e-42 5FGE-J nrPDB 164 3e-41 3WXR-K nrPDB 164 3e-41 3NZW-L nrPDB 163 4e-41 5FMG-N nrPDB 163 7e-41 5GJQ-g nrPDB 161 1e-40 6EPE-7 nrPDB 161 2e-40 1IRU-A nrPDB 160 5e-40 5LF6-M nrPDB 160 6e-40 6FVW-g nrPDB 156 6e-39 5FGG-F nrPDB 156 6e-39 5FMG-F nrPDB 155 1e-38 5FMG-J nrPDB 155 2e-38 3NZW-E nrPDB 153 5e-38 5FMG-H nrPDB 149 9e-37 5LF3-J nrPDB 148 2e-36 1Q5R-H nrPDB 145 1e-35 1Q5Q-H nrPDB 142 1e-34 6GOP-M nrPDB 142 1e-34 6EPD-G nrPDB 140 6e-34 2JAY-A nrPDB 137 4e-33 5LZP-A nrPDB 128 2e-30 5FMG-G nrPDB 121 2e-28 5LOY-A nrPDB 118 2e-27 Sequences not found previously or not previously below threshold: 5FMG-B nrPDB 155 2e-38 4Y8P-I nrPDB 149 7e-37 5FMG-K nrPDB 116 9e-27 5FMG-A nrPDB 104 2e-23 5L5W-G nrPDB 103 9e-23 5LOX-A nrPDB 88 2e-18 5NYF-A nrPDB 85 3e-17 5NYW-A nrPDB 81 2e-16 4HO7-A nrPDB 70 6e-13 5JI2-A nrPDB 61 5e-10 5OVU-A nrPDB 52 2e-07 1OFH-G nrPDB 52 2e-07 1M4Y-A nrPDB 46 1e-05 2Z3B-A nrPDB 44 6e-05 3TY6-A nrPDB 38 0.003 1RFZ-A nrPDB 31 0.60 3K57-A nrPDB 30 0.63 1CEV-A nrPDB 29 1.1 1HH2-P nrPDB 29 1.1 3OPY-B nrPDB 29 1.5 1MZD-A nrPDB 29 1.6 5BQ2-A nrPDB 28 3.0 2E21-A nrPDB 28 3.5 2WQK-A nrPDB 28 3.7 5TSG-B nrPDB 28 4.9 6IOK-I nrPDB 27 6.0 1PQ3-A nrPDB 27 7.2 >3H4P-a nrPDB Length = 219 Score = 273 bits (699), Expect = 3e-74, Method: Composition-based stats. Identities = 218/218 (100%), Positives = 218/218 (100%) Query: 7 TTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIVRLLI 66 TTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIVRLLI Sbjct: 2 TTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIVRLLI 61 Query: 67 AEAKLYKMRTGRNIPPLACATLLSNILHSSRMFPFLTQIIIGGYDLLEGAKLFSLDPLGG 126 AEAKLYKMRTGRNIPPLACATLLSNILHSSRMFPFLTQIIIGGYDLLEGAKLFSLDPLGG Sbjct: 62 AEAKLYKMRTGRNIPPLACATLLSNILHSSRMFPFLTQIIIGGYDLLEGAKLFSLDPLGG 121 Query: 127 MNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERDTFSGNGISLAV 186 MNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERDTFSGNGISLAV Sbjct: 122 MNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERDTFSGNGISLAV 181 Query: 187 ITKDGVKIFEDEEIEKILDSMKAKPKKKTTKRSRRKSK 224 ITKDGVKIFEDEEIEKILDSMKAKPKKKTTKRSRRKSK Sbjct: 182 ITKDGVKIFEDEEIEKILDSMKAKPKKKTTKRSRRKSK 219 >3NZW-K nrPDB Length = 287 Score = 233 bits (595), Expect = 4e-62, Method: Composition-based stats. Identities = 61/211 (28%), Positives = 111/211 (52%), Gaps = 1/211 (0%) Query: 1 MDVMKGTTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQA 60 + + GTTT+ +I+A D RA+ GN VA + KK+ +I+ ++ T+AG D Q Sbjct: 70 IKIAHGTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQF 129 Query: 61 IVRLLIAEAKLYKMRTGRNIPPLACATLLSNILHSSRMFPFLTQIIIGGYDLLEGAKLFS 120 L ++ +L+++R I A + +LSN+++ + +I GY EG ++ Sbjct: 130 WETWLGSQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMICGYTRKEGPTIYY 189 Query: 121 LDPLGGMNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERDTFSGN 180 +D G + F GSG AYGVL++ Y D+SVE+ + L ++ +A RD +SG Sbjct: 190 VDSDGTRLKGDIF-CVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGG 248 Query: 181 GISLAVITKDGVKIFEDEEIEKILDSMKAKP 211 ++L +T+DG + ++ ++ +K + Sbjct: 249 SVNLYHVTEDGWIYHGNHDVGELFWKVKEEE 279 >6EPF-5 nrPDB Length = 263 Score = 229 bits (583), Expect = 1e-60, Method: Composition-based stats. Identities = 63/209 (30%), Positives = 107/209 (51%), Gaps = 2/209 (0%) Query: 1 MDVMKGTTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQA 60 ++++ GTTT+ VI+A D RA+ G +A + KK+ +I+ Y+ T+AG D Sbjct: 54 IEMLHGTTTLAFKFQHGVIVAADSRATAGPYIASQTVKKVIEINPYLLGTMAGGAADCSF 113 Query: 61 IVRLLIAEAKLYKMRTGRNIPPLACATLLSNILHSSRMFPFLTQIIIGGYDLLEGAKLFS 120 RLL + ++Y++R I A + LL+N+++ + +I G+D G L+ Sbjct: 114 WERLLARQCRIYELRNKERISVAAASKLLANMVYQYKGMGLSMGTMICGWD-KRGPGLYY 172 Query: 121 LDPLGGMNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERDTFSGN 180 +D G F+ GSGS A+GV++ GY D+ VEE LA A+ A RD +SG Sbjct: 173 VDSEGNRISGTAFS-VGSGSVYAFGVMDRGYSYDLQVEEAYDLARRAIYQATYRDAYSGG 231 Query: 181 GISLAVITKDGVKIFEDEEIEKILDSMKA 209 ++L + +DG + + + D + Sbjct: 232 AVNLYHVREDGWIRVSSDNVADLHDKYTS 260 >5L5A-K nrPDB Length = 211 Score = 227 bits (580), Expect = 2e-60, Method: Composition-based stats. Identities = 65/205 (31%), Positives = 107/205 (52%), Gaps = 2/205 (0%) Query: 7 TTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIVRLLI 66 TTT+ VI A D RAS G+ ++ K+ +I+ Y+ T++G D Q LL Sbjct: 1 TTTLAFKFQHGVIAAVDSRASAGSYISALRVNKVIEINPYLLGTMSGCAADCQYWETLLA 60 Query: 67 AEAKLYKMRTGRNIPPLACATLLSNILHSSRMFPFLTQIIIGGYDLLEGAKLFSLDPLGG 126 E +LY +R G I A + LLSN++ R +I G+D +G L+ +D G Sbjct: 61 KECRLYYLRNGERISVSAASKLLSNMMCQYRGMGLSMGSMICGWD-KKGPGLYYVDEHGT 119 Query: 127 MNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERDTFSGNGISLAV 186 F+ TGSG+ AYGVL++ Y D+SVE+ + L ++ +A RD +SG ++L Sbjct: 120 RLSGNMFS-TGSGNTYAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSVNLYH 178 Query: 187 ITKDGVKIFEDEEIEKILDSMKAKP 211 +T+DG + ++ ++ +K + Sbjct: 179 VTEDGWIYHGNHDVGELFWKVKEEE 203 >5CZ8-K nrPDB Length = 221 Score = 225 bits (574), Expect = 1e-59, Method: Composition-based stats. Identities = 60/211 (28%), Positives = 110/211 (52%), Gaps = 1/211 (0%) Query: 1 MDVMKGTTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQA 60 + + GTTT+ +I+A D RA+ GN VA + K + +I+ ++ T+AG D Q Sbjct: 4 IKIAHGTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKAVIEINPFLLGTMAGGAADCQF 63 Query: 61 IVRLLIAEAKLYKMRTGRNIPPLACATLLSNILHSSRMFPFLTQIIIGGYDLLEGAKLFS 120 L ++ +L+++R I A + +LSN+++ + +I GY EG ++ Sbjct: 64 WETWLGSQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMICGYTRKEGPTIYY 123 Query: 121 LDPLGGMNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERDTFSGN 180 +D G + F GSG AYGVL++ Y D+SVE+ + L ++ +A RD +SG Sbjct: 124 VDSDGTRLKGDIF-CVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGG 182 Query: 181 GISLAVITKDGVKIFEDEEIEKILDSMKAKP 211 ++L +T+DG + ++ ++ +K + Sbjct: 183 SVNLYHVTEDGWIYHGNHDVGELFWKVKEEE 213 >5L64-K nrPDB Length = 211 Score = 225 bits (573), Expect = 1e-59, Method: Composition-based stats. Identities = 63/205 (30%), Positives = 109/205 (53%), Gaps = 2/205 (0%) Query: 7 TTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIVRLLI 66 TTT+ VI+A D RA+ G +A + KK+ +I+ Y+ T+AG D RLL Sbjct: 1 TTTLAFKFRHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAADCSFWERLLA 60 Query: 67 AEAKLYKMRTGRNIPPLACATLLSNILHSSRMFPFLTQIIIGGYDLLEGAKLFSLDPLGG 126 + ++Y++R I A + LL+N+++ + +I G+D G L+ +D G Sbjct: 61 RQCRIYELRNKERISVAAASKLLANMVYQYKGMGLSMGTMICGWD-KRGPGLYYVDSEGN 119 Query: 127 MNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERDTFSGNGISLAV 186 TF+ GSGS AYGVL++ Y D+SVE+ + L ++ +A RD +SG ++L Sbjct: 120 RISGATFS-VGSGSVYAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSVNLYH 178 Query: 187 ITKDGVKIFEDEEIEKILDSMKAKP 211 +T+DG + ++ ++ +K + Sbjct: 179 VTEDGWIYHGNHDVGELFWKVKEEE 203 >5LN3-5 nrPDB Length = 263 Score = 224 bits (571), Expect = 3e-59, Method: Composition-based stats. Identities = 63/207 (30%), Positives = 107/207 (51%), Gaps = 2/207 (0%) Query: 1 MDVMKGTTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQA 60 ++++ GTTT+ VI+A D RA+ G +A + KK+ +I+ Y+ T+AG D Sbjct: 54 IEMLHGTTTLAFKFRHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAADCSF 113 Query: 61 IVRLLIAEAKLYKMRTGRNIPPLACATLLSNILHSSRMFPFLTQIIIGGYDLLEGAKLFS 120 RLL + ++Y++R I A + LL+N+++ + +I G+D G L+ Sbjct: 114 WERLLARQCRIYELRNKERISVAAASKLLANMVYQYKGMGLSMGTMICGWD-KRGPGLYY 172 Query: 121 LDPLGGMNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERDTFSGN 180 +D G TF+ GSGS AYGV++ GY D+ VE+ LA A+ A RD +SG Sbjct: 173 VDSEGNRISGATFS-VGSGSVYAYGVMDRGYSYDLEVEQAYDLARRAIYQATYRDAYSGG 231 Query: 181 GISLAVITKDGVKIFEDEEIEKILDSM 207 ++L + +DG + + + + Sbjct: 232 AVNLYHVREDGWIRVSSDNVADLHEKY 258 >6AVO-C nrPDB Length = 204 Score = 222 bits (565), Expect = 1e-58, Method: Composition-based stats. Identities = 65/203 (32%), Positives = 104/203 (51%), Gaps = 2/203 (0%) Query: 7 TTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIVRLLI 66 TTT+ VI A D RAS G+ ++ K+ +I+ Y+ T++G D Q RLL Sbjct: 1 TTTLAFKFQHGVIAAVDSRASAGSYISALRVNKVIEINPYLLGTMSGCAADCQYWERLLA 60 Query: 67 AEAKLYKMRTGRNIPPLACATLLSNILHSSRMFPFLTQIIIGGYDLLEGAKLFSLDPLGG 126 E +LY +R G I A + LLSN++ R +I G+D +G L+ +D G Sbjct: 61 KECRLYYLRNGERISVSAASKLLSNMMCQYRGMGLSMGSMICGWD-KKGPGLYYVDEHGT 119 Query: 127 MNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERDTFSGNGISLAV 186 F+ TGSG+ AYGV+++GY ++S EE L A+ A RD++SG +++ Sbjct: 120 RLSGNMFS-TGSGNTYAYGVMDSGYRPNLSPEEAYDLGRRAIAYATHRDSYSGGVVNMYH 178 Query: 187 ITKDGVKIFEDEEIEKILDSMKA 209 + +DG E ++ +L + Sbjct: 179 MKEDGWVKVESTDVSDLLHQYRE 201 >6EPC-1 nrPDB Length = 238 Score = 217 bits (553), Expect = 3e-57, Method: Composition-based stats. Identities = 67/212 (31%), Positives = 107/212 (50%), Gaps = 4/212 (1%) Query: 2 DVMKGTTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAI 61 +V GTT + + D V+L D R + G+ +A++ KL I D+I +GS D QA+ Sbjct: 29 EVSTGTTIMAVQFDGGVVLGADSRTTTGSYIANRVTDKLTPIHDHIFCCRSGSAADTQAV 88 Query: 62 VRLLIAEAKLYKMRTGRNIPPLACATLLSNILHSSRMFPFLTQIIIGGYDLLEGAKLFSL 121 + + + + A+L + + R + III G+D EG +++S+ Sbjct: 89 ADAVTYQLGFHSIELNEPPLVHTAASLFKEMCYRYRE-DLMAGIIIAGWDPQEGGQVYSV 147 Query: 122 DPLGGMNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERDTFSGNG 181 P+GGM ++F GSGS YG ++A Y M+ +E ++ NAL AMERD SG Sbjct: 148 -PMGGMMVRQSFAIGGSGSSYIYGYVDATYREGMTKDECLQFTANALALAMERDGSSGGV 206 Query: 182 ISLAVITKDGVK--IFEDEEIEKILDSMKAKP 211 I LA I + GV+ + ++I K+ S P Sbjct: 207 IRLAAIQQSGVERQVLLGDQIPKVTISTLPPP 238 >3UNF-K nrPDB Length = 204 Score = 216 bits (551), Expect = 5e-57, Method: Composition-based stats. Identities = 65/203 (32%), Positives = 105/203 (51%), Gaps = 2/203 (0%) Query: 7 TTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIVRLLI 66 TTT+ VI+A D RA+ G+ ++ K+ +I+ Y+ T++G D Q RLL Sbjct: 1 TTTLAFKFQHGVIVAVDSRATAGSYISSLRMNKVIEINPYLLGTMSGCAADCQYWERLLA 60 Query: 67 AEAKLYKMRTGRNIPPLACATLLSNILHSSRMFPFLTQIIIGGYDLLEGAKLFSLDPLGG 126 E +LY +R G I A + LLSN++ R +I G+D +G L+ +D G Sbjct: 61 KECRLYYLRNGERISVSAASKLLSNMMLQYRGMGLSMGSMICGWD-KKGPGLYYVDDNGT 119 Query: 127 MNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERDTFSGNGISLAV 186 + F+ TGSG+ AYGV+++GY +D+S EE L A+ A RD +SG +++ Sbjct: 120 RLSGQMFS-TGSGNTYAYGVMDSGYRQDLSPEEAYDLGRRAIAYATHRDNYSGGVVNMYH 178 Query: 187 ITKDGVKIFEDEEIEKILDSMKA 209 + +DG E ++ +L Sbjct: 179 MKEDGWVKVESSDVSDLLYKYGE 201 >6EPF-2 nrPDB Length = 277 Score = 215 bits (549), Expect = 9e-57, Method: Composition-based stats. Identities = 62/221 (28%), Positives = 102/221 (46%), Gaps = 13/221 (5%) Query: 4 MKGTTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIVR 63 GTT G++ D ++L D RA+ G +VADK K++ I I AG+ D + Sbjct: 41 KTGTTIAGVVYKDGIVLGADTRATEGMVVADKNCSKIHFISPNIYCCGAGTAADTDMTTQ 100 Query: 64 LLIAEAKLYKMRTGRNIPPLACATLLSNILHSSRMFPFLTQIIIGGYDLLEGAKLFSLDP 123 L+ + +L+ + TGR + +L +L + + +++GG D+ G L+S+ P Sbjct: 101 LISSNLELHSLTTGRLPRVVTANRMLKQMLFRYQGY-IGAALVLGGVDV-TGPHLYSIYP 158 Query: 124 LGGMNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERDTFSGNGIS 183 G ++ + GSGS A V E + DM EE KL A+ + + D SG+ I Sbjct: 159 HGS-TDKLPYVTMGSGSLAAMAVFEDKFRPDMEEEEAKKLVSEAIAAGIFNDLGSGSNID 217 Query: 184 LAVITKDGVKIFEDEEIEKILDSMKAKPKKKTTKRSRRKSK 224 L VI+K + + P KK T+ R + + Sbjct: 218 LCVISKSKLDFLRPYSV----------PNKKGTRFGRYRCE 248 >6HEC-1 nrPDB Length = 202 Score = 214 bits (546), Expect = 2e-56, Method: Composition-based stats. Identities = 103/202 (50%), Positives = 144/202 (71%), Gaps = 1/202 (0%) Query: 7 TTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIVRLLI 66 TTTVGL+C D V++AT+KRA++GN +A K AKK+Y+I D +AMT AGSVGDAQ + R++ Sbjct: 1 TTTVGLVCKDGVVMATEKRATMGNFIASKAAKKIYQIADRMAMTTAGSVGDAQFLARIIK 60 Query: 67 AEAKLYKMRTGRNIPPLACATLLSNILHSSRMFPFLTQIIIGGYDLLEGAKLFSLDPLGG 126 EA LY++R R A ATL SN+L+S R FP+L Q++IGG D EG ++S+DP+GG Sbjct: 61 IEANLYEIRRERKPTVRAIATLTSNLLNSYRYFPYLVQLLIGGID-SEGKSIYSIDPIGG 119 Query: 127 MNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERDTFSGNGISLAV 186 EEK ATGSGS AYGVLE + ++ V+E ++LA+ A+ SAM+RD+ SG+GI + Sbjct: 120 AIEEKDIVATGSGSLTAYGVLEDRFTPEIGVDEAVELAVRAIYSAMKRDSASGDGIDVVK 179 Query: 187 ITKDGVKIFEDEEIEKILDSMK 208 IT+D + EE+E+IL + Sbjct: 180 ITEDEFYQYSPEEVEQILAKFR 201 >5GJQ-a nrPDB Length = 239 Score = 213 bits (543), Expect = 5e-56, Method: Composition-based stats. Identities = 66/211 (31%), Positives = 104/211 (49%), Gaps = 4/211 (1%) Query: 2 DVMKGTTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAI 61 +V GTT + + D V+L D R + G+ +A++ KL I D I +GS D QA+ Sbjct: 30 EVSTGTTIMAVQFDGGVVLGADSRTTTGSYIANRVTDKLTPIHDRIFCCRSGSAADTQAV 89 Query: 62 VRLLIAEAKLYKMRTGRNIPPLACATLLSNILHSSRMFPFLTQIIIGGYDLLEGAKLFSL 121 + + + + A+L + + R + III G+D EG +++S+ Sbjct: 90 ADAVTYQLGFHSIELNEPPLVHTAASLFKEMCYRYRE-DLMAGIIIAGWDPQEGGQVYSV 148 Query: 122 DPLGGMNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERDTFSGNG 181 P+GGM ++F GSGS YG ++A Y M+ EE ++ NAL AMERD SG Sbjct: 149 -PMGGMMVRQSFAIGGSGSSYIYGYVDATYREGMTKEECLQFTANALALAMERDGSSGGV 207 Query: 182 ISLAVITKDGVK--IFEDEEIEKILDSMKAK 210 I LA I + GV+ + ++I K + Sbjct: 208 IRLAAIAESGVERQVLLGDQIPKFAVATLPP 238 >5L4G-8 nrPDB Length = 277 Score = 211 bits (538), Expect = 2e-55, Method: Composition-based stats. Identities = 61/221 (27%), Positives = 102/221 (46%), Gaps = 13/221 (5%) Query: 4 MKGTTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIVR 63 GTT G++ D ++L D RA+ G +VADK K++ I I AG+ D + Sbjct: 41 KTGTTIAGVVYKDGIVLGADTRATEGMVVADKNCSKIHFISPNIYCCGAGTAADTDMTTQ 100 Query: 64 LLIAEAKLYKMRTGRNIPPLACATLLSNILHSSRMFPFLTQIIIGGYDLLEGAKLFSLDP 123 L+ + +L+ + TGR + +L +L + + +++GG D+ G L+S+ P Sbjct: 101 LISSNLELHSLSTGRLPRVVTANRMLKQMLFRYQGY-IGAALVLGGVDV-TGPHLYSIYP 158 Query: 124 LGGMNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERDTFSGNGIS 183 G ++ + GSGS A V E + DM EE L A+ + + D SG+ I Sbjct: 159 HGS-TDKLPYVTMGSGSLAAMAVFEDKFRPDMEEEEAKNLVSEAIAAGIFNDLGSGSNID 217 Query: 184 LAVITKDGVKIFEDEEIEKILDSMKAKPKKKTTKRSRRKSK 224 L VI+K+ + + P KK T+ R + + Sbjct: 218 LCVISKNKLDFLRPYTV----------PNKKGTRLGRYRCE 248 >3UNB-K nrPDB Length = 205 Score = 210 bits (536), Expect = 3e-55, Method: Composition-based stats. Identities = 63/203 (31%), Positives = 102/203 (50%), Gaps = 2/203 (0%) Query: 7 TTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIVRLLI 66 TTT+ VI+A D RA+ G +A + KK+ +I+ Y+ T+AG D RLL Sbjct: 1 TTTLAFKFLHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAADCSFWERLLA 60 Query: 67 AEAKLYKMRTGRNIPPLACATLLSNILHSSRMFPFLTQIIIGGYDLLEGAKLFSLDPLGG 126 + ++Y++R I A + LL+N+++ + +I G+D G L+ +D G Sbjct: 61 RQCRIYELRNKERISVAAASKLLANMVYQYKGMGLSMGTMICGWD-KRGPGLYYVDSEGN 119 Query: 127 MNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERDTFSGNGISLAV 186 F+ GSGS AYGV++ GY D+ VEE LA A+ A RD +SG ++L Sbjct: 120 RISGTAFS-VGSGSVYAYGVMDRGYSYDLKVEEAYDLARRAIYQATYRDAYSGGAVNLYH 178 Query: 187 ITKDGVKIFEDEEIEKILDSMKA 209 + +DG + + + D + Sbjct: 179 VREDGWIRVSSDNVADLHDKYSS 201 >6HUB-H nrPDB Length = 234 Score = 207 bits (526), Expect = 4e-54, Method: Composition-based stats. Identities = 60/218 (27%), Positives = 100/218 (45%), Gaps = 13/218 (5%) Query: 7 TTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIVRLLI 66 TT G++ D ++L D RA+ G +VADK K++ I I AG+ D +L+ Sbjct: 1 TTIAGVVYKDGIVLGADTRATEGMVVADKNCSKIHFISPNIYCCGAGTAADTDMTTQLIS 60 Query: 67 AEAKLYKMRTGRNIPPLACATLLSNILHSSRMFPFLTQIIIGGYDLLEGAKLFSLDPLGG 126 + +L+ + TGR + +L +L + + +++GG D+ G L+S+ P G Sbjct: 61 SNLELHSLSTGRLPRVVTANRMLKQMLFRYQGY-IGAALVLGGVDV-TGPHLYSIYPHGS 118 Query: 127 MNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERDTFSGNGISLAV 186 ++ + GSGS A V E + DM EE L A+ + + D SG I L V Sbjct: 119 -TDKLPYVTMGSGSLAAMAVFEDKFRPDMEEEEAKNLVSEAIAAGIFNDLGSGGNIDLCV 177 Query: 187 ITKDGVKIFEDEEIEKILDSMKAKPKKKTTKRSRRKSK 224 I+K+ + + P KK T+ R + + Sbjct: 178 ISKNKLDFLRPYTV----------PNKKGTRLGRYRCE 205 >5FMG-L nrPDB Length = 211 Score = 204 bits (520), Expect = 2e-53, Method: Composition-based stats. Identities = 69/209 (33%), Positives = 114/209 (54%), Gaps = 4/209 (1%) Query: 7 TTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIVRLLI 66 TTT+ D +I+A D RAS+G+ ++ + +K+ +I+ I T+AG D + L Sbjct: 1 TTTLAFKFKDGIIVAVDSRASMGSFISSQNVEKIIEINKNILGTMAGGAADCLYWEKYLG 60 Query: 67 AEAKLYKMRTGRNIPPLACATLLSNILHSSRMFPFLTQIIIGGYDLLEGAKLFSLDPLGG 126 K+Y++R I A +T+LSNIL+ + + II+ GYD G +F +D G Sbjct: 61 KIIKIYELRNNEKISVRAASTILSNILYQYKGYGLCCGIILSGYD-HTGFNMFYVDDSGK 119 Query: 127 MNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERDTFSGNGISLAV 186 E F+ GSGS AY +L++ YD ++++++ ++LA NA+ A RD SG + + Sbjct: 120 KVEGNLFSC-GSGSTYAYSILDSAYDYNLNLDQAVELARNAIYHATFRDGGSGGKVRVFH 178 Query: 187 ITKDGV-KIFEDEEIEKILDSMKAKPKKK 214 I K+G KI E E++ L P++K Sbjct: 179 IHKNGYDKIIEGEDVFD-LHYHYTNPEQK 206 >5LEZ-N nrPDB Length = 205 Score = 203 bits (516), Expect = 6e-53, Method: Composition-based stats. Identities = 64/206 (31%), Positives = 101/206 (49%), Gaps = 4/206 (1%) Query: 7 TTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIVRLLI 66 TT + + D V+L D R + G+ +A++ KL I D I +GS D QA+ + Sbjct: 1 TTIMAVQFDGGVVLGADSRTTTGSYIANRVTDKLTPIHDRIFCCRSGSAADTQAVADAVT 60 Query: 67 AEAKLYKMRTGRNIPPLACATLLSNILHSSRMFPFLTQIIIGGYDLLEGAKLFSLDPLGG 126 + + + A+L + + R + III G+D EG +++S+ P+GG Sbjct: 61 YQLGFHSIELNEPPLVHTAASLFKEMCYRYRE-DLMAGIIIAGWDPQEGGQVYSV-PMGG 118 Query: 127 MNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERDTFSGNGISLAV 186 M ++F GSGS YG ++A Y M+ EE ++ NAL AMERD SG I LA Sbjct: 119 MMVRQSFAIGGSGSSYIYGYVDATYREGMTKEECLQFTANALALAMERDGSSGGVIRLAA 178 Query: 187 ITKDGVK--IFEDEEIEKILDSMKAK 210 I + GV+ + ++I K + Sbjct: 179 IAESGVERQVLLGDQIPKFAVATLPP 204 >3IPM-H nrPDB Length = 217 Score = 199 bits (507), Expect = 6e-52, Method: Composition-based stats. Identities = 91/206 (44%), Positives = 135/206 (65%), Gaps = 4/206 (1%) Query: 3 VMKGTTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIV 62 + GTTTVG+ DAVI+AT++R ++ N + K KKL++ID Y MTIAG VGDAQ +V Sbjct: 5 LETGTTTVGITLKDAVIMATERRVTMENFIMHKNGKKLFQIDTYTGMTIAGLVGDAQVLV 64 Query: 63 RLLIAEAKLYKMRTGRNIPPLACATLLSNILHSSRMFPFLTQIIIGGYDLLEGAKLFSLD 122 R + AE +LY+++ N+P A ATLLSN+L+ + P++ Q+++GG D +FS+D Sbjct: 65 RYMKAELELYRLQRRVNMPIEAVATLLSNMLNQVKYMPYMVQLLVGGID--TAPHVFSID 122 Query: 123 PLGGMNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERDTFSGNGI 182 GG + E + +TGSGSP YGVLE+ Y M+V+EG+ L + A+ +A +RD+ SG I Sbjct: 123 AAGG-SVEDIYASTGSGSPFVYGVLESQYSEKMTVDEGVDLVIRAISAAKQRDSASGGMI 181 Query: 183 SLAVIT-KDGVKIFEDEEIEKILDSM 207 +AVIT KDG ++IE + + Sbjct: 182 DVAVITRKDGYVQLPTDQIESRIRKL 207 >5FMG-I nrPDB Length = 229 Score = 199 bits (507), Expect = 8e-52, Method: Composition-based stats. Identities = 67/205 (32%), Positives = 99/205 (48%), Gaps = 3/205 (1%) Query: 7 TTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIVRLLI 66 TT GL+C +AVIL D RA+ G +VADK KL+ I I AG GD + L Sbjct: 1 TTICGLVCQNAVILGADTRATEGPIVADKNCSKLHYISKNIWCAGAGVAGDLEHTTLWLQ 60 Query: 67 AEAKLYKMRTGRNIPPLACATLLSNILHSSRMFPFLTQIIIGGYDLLEGAKLFSLDPLGG 126 +L+++ T C + L+ L + + + I++GG D+ G +L+ + P G Sbjct: 61 HNVELHRLNTNTQPRVSMCVSRLTQELFKYQGYK-VCAIVLGGVDV-NGPQLYGIHPHGS 118 Query: 127 MNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERDTFSGNGISLAV 186 FTA GSGS A VLEA Y +M++EEG L A+ + + D SG + + V Sbjct: 119 SC-LLPFTALGSGSLNAMAVLEAKYRDNMTIEEGKNLVCEAICAGIFNDLGSGGNVDICV 177 Query: 187 ITKDGVKIFEDEEIEKILDSMKAKP 211 ITKD + + + P Sbjct: 178 ITKDSYQHIRPYKEPNMRLYHLPHP 202 >2Z5C-C nrPDB Length = 262 Score = 198 bits (505), Expect = 1e-51, Method: Composition-based stats. Identities = 54/228 (23%), Positives = 105/228 (46%), Gaps = 14/228 (6%) Query: 3 VMKGTTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIV 62 + G+T +G+ + V+L +KRA+ L+ +K+ +ID +I ++G DA++++ Sbjct: 33 IKLGSTAIGIATKEGVVLGVEKRAT-SPLLESDSIEKIVEIDRHIGCAMSGLTADARSMI 91 Query: 63 RLLIAEAKLYKMRTGRNIPPLACATLLSNILHSSRM----------FPFLTQIIIGGYDL 112 A + + +I + + ++ PF ++I G+D Sbjct: 92 EHARTAAVTHNLYYDEDINVESLTQSVCDLALRFGEGASGEERLMSRPFGVALLIAGHDA 151 Query: 113 LEGAKLFSLDPLGGMNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAM 172 +G +LF +P G A GSGS A L + ++++E L L LK M Sbjct: 152 DDGYQLFHAEPSGTFYRYNA-KAIGSGSEGAQAELLNEWHSSLTLKEAELLVLKILKQVM 210 Query: 173 ERDTFSGNGISLAVITK-DGVKIFEDEEIEKILDSMKAKPKKKTTKRS 219 E + N L+ ITK DG KI+++E+ +++ +K K ++ + + Sbjct: 211 E-EKLDENNAQLSCITKQDGFKIYDNEKTAELIKELKEKEAAESPEEA 257 >1G0U-D nrPDB Length = 241 Score = 197 bits (501), Expect = 3e-51, Method: Composition-based stats. Identities = 55/214 (25%), Positives = 105/214 (49%), Gaps = 5/214 (2%) Query: 3 VMKGTTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIV 62 + G+T +G+ + V+L +KRA+ L+ +K+ +ID +I ++G DA++++ Sbjct: 31 IKLGSTAIGIATKEGVVLGVEKRAT-SPLLESDSIEKIVEIDRHIGCAMSGLTADARSMI 89 Query: 63 RLLIAEAKLYKMRTGRNIPPLACATLLSNILHSSRM-FPFLTQIIIGGYDLLEGAKLFSL 121 A + + +I + + ++ ++ M PF ++I G+D +G +LF Sbjct: 90 EHARTAAVTHNLYYDEDINVESLTQSVCDLAAAAAMSRPFGVALLIAGHDADDGYQLFHA 149 Query: 122 DPLGGMNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERDTFSGNG 181 +P G A GSGS A L + ++++E L L LK ME + N Sbjct: 150 EPSGTFYRYNA-KAIGSGSEGAQAELLNEWHSSLTLKEAELLVLKILKQVME-EKLDENN 207 Query: 182 ISLAVITK-DGVKIFEDEEIEKILDSMKAKPKKK 214 L+ ITK DG KI+++E+ +++ +K K + Sbjct: 208 AQLSCITKQDGFKIYDNEKTAELIKELKEKEAAE 241 >6AVO-A nrPDB Length = 199 Score = 193 bits (492), Expect = 4e-50, Method: Composition-based stats. Identities = 62/202 (30%), Positives = 98/202 (48%), Gaps = 5/202 (2%) Query: 7 TTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIVRLLI 66 TT + + D V++ +D R S G V ++ KL + + I ++GS DAQA+ + Sbjct: 1 TTIMAVEFDGGVVMGSDSRVSAGEAVVNRVFDKLSPLHERIYCALSGSAADAQAVADMAA 60 Query: 67 AEAKLYKMRTGRNIPPLACATLLSNILHSSRMFPFLTQIIIGGYDLLEGAKLFSLDPLGG 126 + +L+ + LA A ++ NI + R +++ G+D EG +++ LGG Sbjct: 61 YQLELHGIELEEPPLVLAAANVVRNISYKYRE-DLSAHLMVAGWDQREGGQVYGT--LGG 117 Query: 127 MNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERDTFSGNGISLAV 186 M + F GSGS YG ++A Y MS EE + +A+ AM RD SG I L Sbjct: 118 MLTRQPFAIGGSGSTFIYGYVDAAYKPGMSPEECRRFTTDAIALAMSRDGSSGGVIYLVT 177 Query: 187 ITKDGV--KIFEDEEIEKILDS 206 IT GV ++ E+ K D Sbjct: 178 ITAAGVDHRVILGNELPKFYDE 199 >5MPC-h nrPDB Length = 215 Score = 192 bits (487), Expect = 1e-49, Method: Composition-based stats. Identities = 58/204 (28%), Positives = 101/204 (49%), Gaps = 5/204 (2%) Query: 2 DVMKGTTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAI 61 +V GT+ + + D VIL D R + G +A++ KL ++ D I +GS D QAI Sbjct: 15 EVSLGTSIMAVTFKDGVILGADSRTTTGAYIANRVTDKLTRVHDKIWCCRSGSAADTQAI 74 Query: 62 VRLLIAEAKLYKMRTGRNIPPLACATLLSNILHSSRMFPFLTQIIIGGYDLLEGAKLFSL 121 ++ +LY + G A++ + + ++ II+ GYD +++++ Sbjct: 75 ADIVQYHLELYTSQYGTP-STETAASVFKELCYENKDN-LTAGIIVAGYDDKNKGEVYTI 132 Query: 122 DPLGGMNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERDTFSGNG 181 PLGG + + GSGS YG + + +MS EE + ++L A++ D SG Sbjct: 133 -PLGGSVHKLPYAIAGSGSTFIYGYCDKNFRENMSKEETVDFIKHSLSQAIKWDGSSGGV 191 Query: 182 ISLAVITKDGVK--IFEDEEIEKI 203 I + V+T GV+ IF +E E++ Sbjct: 192 IRMVVLTAAGVERLIFYPDEYEQL 215 >3UNH-H nrPDB Length = 234 Score = 191 bits (486), Expect = 2e-49, Method: Composition-based stats. Identities = 60/216 (27%), Positives = 97/216 (44%), Gaps = 13/216 (6%) Query: 7 TTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIVRLLI 66 TT GL+ D VIL D RA+ ++VADK +K++ I I AG D + R+ Sbjct: 1 TTIAGLVFRDGVILGADTRATNDSVVADKSCEKIHFIAPKIYCCGAGVAADTEMTTRMAA 60 Query: 67 AEAKLYKMRTGRNIPPLACATLLSNILHSSRMFPFLTQIIIGGYDLLEGAKLFSLDPLGG 126 ++ +L+ + TGR +L L + +++GG DL G +L+ + P G Sbjct: 61 SKMELHALSTGREPRVATVTRILRQTLFRYQGH-VGASLVVGGVDL-NGPQLYEVHPHGS 118 Query: 127 MNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERDTFSGNGISLAV 186 FTA GSG A +LE + +M++E +L + A+ + + D SG + V Sbjct: 119 Y-SRLPFTALGSGQGAAVALLEDRFQPNMTLEAAQELLVEAITAGILSDLGSGGNVDACV 177 Query: 187 ITKDGVKIFEDEEIEKILDSMKAKPKKKTTKRSRRK 222 IT G K L + P + + R + Sbjct: 178 ITAGGAK----------LQRALSTPTEPVQRAGRYR 203 >3H4P-A nrPDB Length = 264 Score = 191 bits (485), Expect = 3e-49, Method: Composition-based stats. Identities = 62/198 (31%), Positives = 105/198 (53%), Gaps = 9/198 (4%) Query: 3 VMKGTTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIV 62 V +GTT +G+ C D V+LA D+R + LV + +K+++IDD++A +G V DA+ ++ Sbjct: 35 VRRGTTAIGIACKDGVVLAVDRRIT-SKLVKIRSIEKIFQIDDHVAAATSGLVADARVLI 93 Query: 63 RLLIAEAKLYKMRTGRNIPPLACATLLSNILHSSRM----FPFLTQIIIGGYDLLEGAKL 118 EA++Y++ G I A + +I + PF ++I G D A+L Sbjct: 94 DRARLEAQIYRLTYGEEISIEMLAKKICDIKQAYTQHGGVRPFGVSLLIAGID-KNEARL 152 Query: 119 FSLDPLGGMNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERDTFS 178 F DP G + E K TA GSG P+ +LE Y D++++EG++LA+ AL A + Sbjct: 153 FETDPSGALIEYKA-TAIGSGRPVVMELLEKEYRDDITLDEGLELAITALTKA--NEDIK 209 Query: 179 GNGISLAVITKDGVKIFE 196 + + +IT + + Sbjct: 210 PENVDVCIITVKDAQFKK 227 >6AVO-B nrPDB Length = 234 Score = 190 bits (483), Expect = 4e-49, Method: Composition-based stats. Identities = 63/215 (29%), Positives = 98/215 (45%), Gaps = 13/215 (6%) Query: 7 TTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIVRLLI 66 TT GL+ D VIL D RA+ ++VADK +K++ I I AG DA+ R++ Sbjct: 1 TTIAGLVFQDGVILGADTRATNDSVVADKSCEKIHFIAPKIYCCGAGVAADAEMTTRMVA 60 Query: 67 AEAKLYKMRTGRNIPPLACATLLSNILHSSRMFPFLTQIIIGGYDLLEGAKLFSLDPLGG 126 ++ +L+ + TGR +L L + +I+GG DL G +L+ + P G Sbjct: 61 SKMELHALSTGREPRVATVTRILRQTLFRYQGH-VGASLIVGGVDL-TGPQLYGVHPHGS 118 Query: 127 MNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERDTFSGNGISLAV 186 FTA GSG A VLE + +M++E L + A+ + + D SG + V Sbjct: 119 Y-SRLPFTALGSGQDAALAVLEDRFQPNMTLEAAQGLLVEAVTAGILGDLGSGGNVDACV 177 Query: 187 ITKDGVKIFEDEEIEKILDSMKAKPKKKTTKRSRR 221 ITK G K+ + P + + R Sbjct: 178 ITKTGAKLLR----------TLSSPTEPVKRSGRY 202 >5FMG-E nrPDB Length = 256 Score = 189 bits (480), Expect = 1e-48, Method: Composition-based stats. Identities = 63/221 (28%), Positives = 104/221 (47%), Gaps = 17/221 (7%) Query: 3 VMKGTTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIV 62 + G+T VG+ +D VILA+++R S L+ +KL IDD+I ++G + DA+ ++ Sbjct: 31 IKLGSTAVGICVNDGVILASERRIS-STLIEKDSVEKLLSIDDHIGCAMSGLMADARTLI 89 Query: 63 RLLIAEAKLYKMRTGRNIPPLACATLLS-------NILHSSRM----FPFLTQIIIGGYD 111 E YK NI +C L+S N+ S R PF ++IGG D Sbjct: 90 DYARVECNHYKFIYNENINIKSCVELISELALDFSNLSDSKRKKIMSRPFGVALLIGGVD 149 Query: 112 LLEGAKLFSLDPLGGMNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSA 171 G L+ +P G + GS A +L+ Y +DM+ E+ LAL L+ Sbjct: 150 -KNGPCLWYTEPSGTNTRFSA-ASIGSAQEGAELLLQENYKKDMTFEQAEILALTVLRQV 207 Query: 172 MERDTFSGNGISLAVITKDGVKIFE--DEEIEKILDSMKAK 210 ME D S + + + I K ++ ++I +I+D + + Sbjct: 208 ME-DKLSTSNVEICAIKKSDQTFYKYNTDDISRIIDVLPSP 247 >5FGI-H nrPDB Length = 244 Score = 188 bits (478), Expect = 2e-48, Method: Composition-based stats. Identities = 61/217 (28%), Positives = 110/217 (50%), Gaps = 7/217 (3%) Query: 4 MKGTTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIVR 63 G T VG+ ++ V++A D R++ G +VADK KL++I I AG+ D +A+ + Sbjct: 10 STGATIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEAVTQ 69 Query: 64 LLIAEAKLYKMRTGRNIPPLACATLLSNILHSSRMFPFLTQIIIGGYDLLEGAKLFSLDP 123 L+ + +L+ + T R ++ +L L + +I+ G D G+ LFS+ Sbjct: 70 LIGSNIELHSLYTSREPRVVSALQMLKQHLFKYQGH-IGAYLIVAGVDP-TGSHLFSIHA 127 Query: 124 LGGMNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERDTFSGNGIS 183 G + + + GSGS A VLE+ + +D++ EE IKLA +A+++ + D SG+ + Sbjct: 128 HGS-TDVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDLGSGSNVD 186 Query: 184 LAVITKDGVKIFEDEEIEKILDSMKAKPKKKTTKRSR 220 + V+ + E + L + K+K+ K R Sbjct: 187 VCVMEIGK----DAEYLRNYLTPNVREEKQKSYKFPR 219 >3UNF-N nrPDB Length = 199 Score = 184 bits (468), Expect = 2e-47, Method: Composition-based stats. Identities = 65/202 (32%), Positives = 100/202 (49%), Gaps = 5/202 (2%) Query: 7 TTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIVRLLI 66 TT + + D V++ +D R S G V ++ KL + I ++GS DAQAI + Sbjct: 1 TTIMAVEFDGGVVVGSDSRVSAGTAVVNRVFDKLSPLHQRIFCALSGSAADAQAIADMAA 60 Query: 67 AEAKLYKMRTGRNIPPLACATLLSNILHSSRMFPFLTQIIIGGYDLLEGAKLFSLDPLGG 126 + +L+ + LA A ++ NI + R L +I+ G+D EG +++ +GG Sbjct: 61 YQLELHGLELEEPPLVLAAANVVKNISYKYRE-DLLAHLIVAGWDQREGGQVYGT--MGG 117 Query: 127 MNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERDTFSGNGISLAV 186 M + FT GSGS YG ++A Y M+ EE + NA+ AM RD SG I L Sbjct: 118 MLIRQPFTIGGSGSSYIYGYVDAAYKPGMTPEECRRFTTNAITLAMNRDGSSGGVIYLVT 177 Query: 187 ITKDGV--KIFEDEEIEKILDS 206 IT GV ++ +E+ K D Sbjct: 178 ITAAGVDHRVILGDELPKFYDE 199 >6J30-C nrPDB Length = 258 Score = 184 bits (467), Expect = 3e-47, Method: Composition-based stats. Identities = 60/215 (27%), Positives = 100/215 (46%), Gaps = 11/215 (5%) Query: 3 VMKGTTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIV 62 + T +G++ D ++LA +++ + L D +KLYK++D IA+ +AG DA+ ++ Sbjct: 29 ISHAGTAIGIMASDGIVLAAERKVTSTLLEQDTSTEKLYKLNDKIAVAVAGLTADAEILI 88 Query: 63 RLLIAEAKLYKMRTGRNIPPLACATLLSNILHSSRM----FPFLTQIIIGGYDLLEGAKL 118 A+ Y +IP LS+I PF I GYD G +L Sbjct: 89 NTARIHAQNYLKTYNEDIPVEILVRRLSDIKQGYTQHGGLRPFGVSFIYAGYDDRYGYQL 148 Query: 119 FSLDPLGGMNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERDTFS 178 ++ +P G K + G+ + A +L+ Y DM V++ I+LAL L + + Sbjct: 149 YTSNPSGNYTGWKAIS-VGANTSAAQTLLQMDYKDDMKVDDAIELALKTLSKTTDSSALT 207 Query: 179 GNGISLAVITK---DG---VKIFEDEEIEKILDSM 207 + + A I K DG KIF+ +EI+ IL Sbjct: 208 YDRLEFATIRKGANDGEVYQKIFKPQEIKDILVKT 242 >6HV7-H nrPDB Length = 226 Score = 183 bits (466), Expect = 4e-47, Method: Composition-based stats. Identities = 63/214 (29%), Positives = 108/214 (50%), Gaps = 7/214 (3%) Query: 7 TTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIVRLLI 66 TT GL+ D VIL D RA+ ++VADK +K++ I I AG DA+A+ +L+ Sbjct: 1 TTIAGLVFQDGVILGADTRATNDSVVADKSCEKIHFIAPKIYCCGAGVAADAEAVTQLIG 60 Query: 67 AEAKLYKMRTGRNIPPLACATLLSNILHSSRMFPFLTQIIIGGYDLLEGAKLFSLDPLGG 126 + +L+ + T R ++ +L L + +I+ G D G+ LFS+ G Sbjct: 61 SNIELHSLYTSREPRVVSALQMLKQHLFKYQGH-IGAYLIVAGVDP-TGSHLFSIHAHGS 118 Query: 127 MNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERDTFSGNGISLAV 186 + + + GSGS A VLE+ + +D++ EE IKLA +A+++ + D SG+ + + V Sbjct: 119 -TDVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDLGSGSNVDVCV 177 Query: 187 ITKDGVKIFEDEEIEKILDSMKAKPKKKTTKRSR 220 + + E + L + K+K+ K R Sbjct: 178 MEIGK----DAEYLRNYLTPNVREEKQKSYKFPR 207 >6HE5-A nrPDB Length = 247 Score = 183 bits (465), Expect = 6e-47, Method: Composition-based stats. Identities = 57/214 (26%), Positives = 96/214 (44%), Gaps = 11/214 (5%) Query: 3 VMKGTTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIV 62 V +G T +G+ C + VIL DKR L AD +K+YKID++I +G V DA+ ++ Sbjct: 32 VKRGATAIGIKCKEGVILIADKRVGSKLLEAD-TIEKIYKIDEHICAATSGLVADARVLI 90 Query: 63 RLLIAEAKLYKMRTGRNIPPLACATLLSNILHSSRMF----PFLTQIIIGGYDLLEGAKL 118 EA++ ++ I A + + + PF ++I G D + KL Sbjct: 91 DRARIEAQINRLTYDEPITVKELAKKICDFKQQYTQYGGVRPFGVSLLIAGVDEV--PKL 148 Query: 119 FSLDPLGGMNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERDTFS 178 + DP G + E K TA G G E Y D+S ++ + L L A+ ++E + Sbjct: 149 YETDPSGALLEYKA-TAIGMGRNAVTEFFEKEYRDDLSFDDAMVLGLVAMGLSIESE-LV 206 Query: 179 GNGISLAVITKDG--VKIFEDEEIEKILDSMKAK 210 I + + D K EE++ ++ + Sbjct: 207 PENIEVGYVKVDDRTFKEVSPEELKPYVERANER 240 >5GJR-F nrPDB Length = 241 Score = 183 bits (464), Expect = 6e-47, Method: Composition-based stats. Identities = 53/215 (24%), Positives = 97/215 (45%), Gaps = 14/215 (6%) Query: 3 VMKGTTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIV 62 + G+T +G+ + V LA +KR + L+ +K+ +ID +I ++G + DA+ ++ Sbjct: 31 IKLGSTAIGIQTSEGVCLAVEKRIT-SPLMEPSSIEKIVEIDAHIGCAMSGLIADAKTLI 89 Query: 63 RLLIAEAKLYKMRTGRNIPPLACATLLSNILHSSRM---------FPFLTQIIIGGYDLL 113 E + + + + +SN+ PF ++ GG D Sbjct: 90 DKARVETQNHWFTYNETMTVESVTQAVSNLALQFGEEDADPGAMSRPFGVALLFGGVDEK 149 Query: 114 EGAKLFSLDPLGGMNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAME 173 G +LF +DP G + A GS S A L+ Y + M+++E IK +L LK ME Sbjct: 150 -GPQLFHMDPSGTFVQCDA-RAIGSASEGAQSSLQEVYHKSMTLKEAIKSSLIILKQVME 207 Query: 174 RDTFSGNGISLAVITK-DGVKIFEDEEIEKILDSM 207 + + I LA + +F EE+E+++ + Sbjct: 208 -EKLNATNIELATVQPGQNFHMFTKEELEEVIKDI 241 >5FMG-D nrPDB Length = 241 Score = 180 bits (456), Expect = 5e-46, Method: Composition-based stats. Identities = 50/215 (23%), Positives = 95/215 (44%), Gaps = 9/215 (4%) Query: 3 VMKGTTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIV 62 V KG V + + +LA +K+ ++ L K +KL K+D++ + AG DA+ +V Sbjct: 26 VKKGGCAVAIKSSNFAVLAVEKK-NIPKLQNPKTTEKLIKLDEHNCLAFAGLNADARVLV 84 Query: 63 RLLIAEAKLYKMRTGRNIPPLACATLLSNI----LHSSRMFPFLTQIIIGGYDLLEGAKL 118 E + Y + P A ++ + H + PF +I G+ + + Sbjct: 85 NKTRLECQRYYLNMDEPAPVDYIAKYVAKVQQKFTHRGGVRPFGIATLIAGFKNNKEICI 144 Query: 119 FSLDPLGGMNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERDTFS 178 + +P G K A G + I LE Y +M ++ I LAL A+ +E S Sbjct: 145 YQTEPSGIYAAWKA-QAIGKNAKIVQEFLEKNYQENMEQKDCIFLALKAIFEVVE---LS 200 Query: 179 GNGISLAVITKDGVKIFEDEEIEKILDSMKAKPKK 213 + +A++T+ + E++EI +++ + + K Sbjct: 201 SKNVEVALLTEKDLTFIEEQEINSMVELIDQERTK 235 >5LE5-B nrPDB Length = 261 Score = 178 bits (453), Expect = 1e-45, Method: Composition-based stats. Identities = 51/211 (24%), Positives = 103/211 (48%), Gaps = 10/211 (4%) Query: 3 VMKGTTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIV 62 + T +G++ +D V+LA ++R L ++K+YK+++ +A ++AG DA + Sbjct: 28 IGHAGTCLGILANDGVLLAAERRNIHKLLDEVFFSEKIYKLNEDMACSVAGITSDANVLT 87 Query: 63 RLLIAEAKLYKMRTGRNIPPLACATLLSNILHSSRMF----PFLTQIIIGGYDLLEGAKL 118 L A+ Y ++ IP T L +I + F PF ++ G+D G +L Sbjct: 88 NELRLIAQRYLLQYQEPIPCEQLVTALCDIKQAYTQFGGKRPFGVSLLYIGWDKHYGFQL 147 Query: 119 FSLDPLGGMNEEKTFTATGSGSPIAYGVLEAGYDR-DMSVEEGIKLALNALKSAMERDTF 177 + DP G K T G+ S A +L+ Y +M+++ + LA+ L M+ Sbjct: 148 YQSDPSGNYGGWKA-TCIGNNSAAAVSMLKQDYKEGEMTLKSALALAIKVLNKTMDVSKL 206 Query: 178 SGNGISLAVITKDG----VKIFEDEEIEKIL 204 S + +A +T++ +++ + +E+E+++ Sbjct: 207 SAEKVEIATLTRENGKTVIRVLKQKEVEQLI 237 >5T0I-L nrPDB Length = 268 Score = 177 bits (448), Expect = 5e-45, Method: Composition-based stats. Identities = 54/222 (24%), Positives = 103/222 (46%), Gaps = 15/222 (6%) Query: 3 VMKGTTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIV 62 V +G+ TVGL +L KRA L A + KK+ +D++I ++IAG DA+ + Sbjct: 34 VKQGSATVGLKSKTHAVLVALKRA-QSELAAHQ--KKILHVDNHIGISIAGLTADARLLC 90 Query: 63 RLLIAEAKLYKMRTGRNIPPLACATLLSNI----LHSSRMFPFLTQIIIGGYDLLEGAKL 118 + E + R +P +L+ + P+ ++I GYD + G + Sbjct: 91 NFMRQECLDSRFVFDRPLPVSRLVSLIGSKTQIPTQRYGRRPYGVGLLIAGYDDM-GPHI 149 Query: 119 FSLDPLGGMNEEKTFTATGSGSPIAYGVLEAGYDRDM--SVEEGIKLALNALKSAM--ER 174 F P + + + G+ S A LE M ++ E +K L AL+ + E+ Sbjct: 150 FQTCPSANYFDCRAMS-IGARSQSARTYLERHMSEFMECNLNELVKHGLRALRETLPAEQ 208 Query: 175 DTFSGNGISLAVITKD-GVKIFEDEEIEKILDSMKAKPKKKT 215 D + +S+ ++ KD I++D+++ L+ ++ +P++K Sbjct: 209 DLTT-KNVSIGIVGKDLEFTIYDDDDVSPFLEGLEERPQRKA 249 >4YA5-C nrPDB Length = 254 Score = 177 bits (448), Expect = 5e-45, Method: Composition-based stats. Identities = 46/214 (21%), Positives = 89/214 (41%), Gaps = 13/214 (6%) Query: 3 VMKGTTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIV 62 V +GT VG+ + V+L ++R++L K+ KID ++ ++ +G D++ ++ Sbjct: 27 VKRGTCAVGVKGKNCVVLGCERRSTLKLQDTRITPSKVSKIDSHVVLSFSGLNADSRILI 86 Query: 63 RLLIAEAKLYKMRTGRNIPPLACATLL----SNILHSSRMFPFLTQIIIGGYDLL-EGAK 117 EA+ +++ + + S + PF +I G+D + K Sbjct: 87 EKARVEAQSHRLTLEDPVTVEYLTRYVAGVQQRYTQSGGVRPFGVSTLIAGFDPRDDEPK 146 Query: 118 LFSLDPLGGMNEEKTFTATGSGSPIAYGVLEAGYD---RDMSVEEGIKLALNALKSAMER 174 L+ +P G + T G S LE YD +VEE +KL + +L ++ Sbjct: 147 LYQTEPSGIYSSWSAQT-IGRNSKTVREFLEKNYDRKEPPATVEECVKLTVRSLLEVVQ- 204 Query: 175 DTFSGNGISLAVITKDG-VKIFEDEEIEKILDSM 207 I + V+ D + EEI + + + Sbjct: 205 --TGAKNIEITVVKPDSDIVALSSEEINQYVTQI 236 >5L4G-U nrPDB Length = 241 Score = 176 bits (446), Expect = 8e-45, Method: Composition-based stats. Identities = 57/200 (28%), Positives = 103/200 (51%), Gaps = 10/200 (5%) Query: 3 VMKGTTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIV 62 V G T + + +D I+A+D R S G + +++ K YK+ D + +G GD + Sbjct: 34 VFNGGTILAIAGEDFAIVASDTRLSEGFSIHTRDSPKCYKLTDKTVIGCSGFHGDCLTLT 93 Query: 63 RLLIAEAKLYKMRTGRNIPPLACATLLSNILHSSRMFPFLTQIIIGGYDLLEGAKLFSLD 122 +++ A K+YK + + A A +LS IL+S R FP+ IIGG D ++S D Sbjct: 94 KIIEARLKMYKHSNNKAMTTGAIAAMLSTILYSRRFFPYYVYNIIGGLDEEGKGAVYSFD 153 Query: 123 PLGGMNEEKTFTATGSGSPIAYGVLEAGY---------DRDMSVEEGIKLALNALKSAME 173 P+G + +F A GS S + +L+ +S++ ++L + SA E Sbjct: 154 PVGSY-QRDSFKAGGSASAMLQPLLDNQVGFKNMQNVEHVPLSLDRAMRLVKDVFISAAE 212 Query: 174 RDTFSGNGISLAVITKDGVK 193 RD ++G+ + + ++TK+G++ Sbjct: 213 RDVYTGDALRICIVTKEGIR 232 >5LF0-A nrPDB Length = 234 Score = 175 bits (445), Expect = 1e-44, Method: Composition-based stats. Identities = 49/209 (23%), Positives = 89/209 (42%), Gaps = 8/209 (3%) Query: 3 VMKGTTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIV 62 V G +VG+ + V+LAT+K+ L ++ K+ I +I + +G D + +V Sbjct: 29 VAGGAPSVGIKAANGVVLATEKK-QKSILYDERSVHKVEPITKHIGLVYSGMGPDYRVLV 87 Query: 63 RLLIAEAKLYKMRTGRNIP----PLACATLLSNILHSSRMFPFLTQIIIGGYDLLEGAKL 118 A+ Y + IP A+++ S + PF ++I G++ L Sbjct: 88 HRARKLAQQYYLVYQEPIPTAQLVQRVASVMQEYTQSGGVRPFGVSLLICGWNEGR-PYL 146 Query: 119 FSLDPLGGMNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERDTFS 178 F DP G K TA G LE Y+ D+ +E+ I A+ LK + E + Sbjct: 147 FQSDPSGAYFAWKA-TAMGKNYVNGKTFLEKRYNEDLELEDAIHTAILTLKESFEGQM-T 204 Query: 179 GNGISLAVITKDGVKIFEDEEIEKILDSM 207 + I + + + G + E++ L ++ Sbjct: 205 EDNIEVGICNEAGFRRLTPTEVKDYLAAI 233 >5VFT-S nrPDB Length = 213 Score = 175 bits (443), Expect = 2e-44, Method: Composition-based stats. Identities = 57/200 (28%), Positives = 103/200 (51%), Gaps = 10/200 (5%) Query: 3 VMKGTTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIV 62 V G T + + +D I+A+D R S G + +++ K YK+ D + +G GD + Sbjct: 6 VFNGGTILAIAGEDFAIVASDTRLSEGFSIHTRDSPKCYKLTDKTVIGCSGFHGDCLTLT 65 Query: 63 RLLIAEAKLYKMRTGRNIPPLACATLLSNILHSSRMFPFLTQIIIGGYDLLEGAKLFSLD 122 +++ A K+YK + + A A +LS IL+S R FP+ IIGG D ++S D Sbjct: 66 KIIEARLKMYKHSNNKAMTTGAIAAMLSTILYSRRFFPYYVYNIIGGLDEEGKGAVYSFD 125 Query: 123 PLGGMNEEKTFTATGSGSPIAYGVLEAGY---------DRDMSVEEGIKLALNALKSAME 173 P+G + +F A GS S + +L+ +S++ ++L + SA E Sbjct: 126 PVGSY-QRDSFKAGGSASAMLQPLLDNQVGFKNMQNVEHVPLSLDRAMRLVKDVFISAAE 184 Query: 174 RDTFSGNGISLAVITKDGVK 193 RD ++G+ + + ++TK+G++ Sbjct: 185 RDVYTGDALRICIVTKEGIR 204 >5LEZ-C nrPDB Length = 248 Score = 174 bits (442), Expect = 2e-44, Method: Composition-based stats. Identities = 58/210 (27%), Positives = 96/210 (45%), Gaps = 12/210 (5%) Query: 3 VMKGTTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIV 62 V KG+T VG+ D V+L +K+ S+ L ++ +K+ +DD + M AG DA+ ++ Sbjct: 26 VKKGSTAVGVRGRDIVVLGVEKK-SVAKLQDERTVRKICALDDNVCMAFAGLTADARIVI 84 Query: 63 RLLIAEAKLYKMRTGRNIPPL----ACATLLSNILHSSRMFPFLTQIIIGGYDLLEGAKL 118 E + +++ + A+L S+ PF +I G+D +L Sbjct: 85 NRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSNGRRPFGISALIVGFDFDGTPRL 144 Query: 119 FSLDPLGGMNEEKTFTATGSGSPIAYGVLEAGYDRDM--SVEEGIKLALNALKSAMERDT 176 + DP G + K A G G+ LE Y + + + IKL + AL ++ Sbjct: 145 YQTDPSGTYHAWKA-NAIGRGAKSVREFLEKNYTDEAIETDDLTIKLVIKALLEVVQS-- 201 Query: 177 FSGNGISLAVITKD-GVKIFEDEEIEKILD 205 G I LAV+ +D +KI EEIEK + Sbjct: 202 -GGKNIELAVMRRDQSLKILNPEEIEKYVA 230 >3UNE-I nrPDB Length = 205 Score = 174 bits (441), Expect = 3e-44, Method: Composition-based stats. Identities = 49/190 (25%), Positives = 95/190 (50%), Gaps = 1/190 (0%) Query: 5 KGTTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIVRL 64 G + + + V +A D+R + + + +K++ + D + + +AG D Q + + Sbjct: 7 NGGAVMAMKGKNCVAIAADRRFGIQAQMVTTDFQKIFPMGDRLYIGLAGLATDVQTVAQR 66 Query: 65 LIAEAKLYKMRTGRNIPPLACATLLSNILHSSRMFPFLTQIIIGGYDLLE-GAKLFSLDP 123 L LY+++ GR I P ++++N+L+ R P+ T+ +I G D + SLD Sbjct: 67 LKFRLNLYELKEGRQIKPYTLMSMVANLLYEKRFGPYYTEPVIAGLDPKTFKPFICSLDL 126 Query: 124 LGGMNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERDTFSGNGIS 183 +G F +G+ S YG+ E+ ++ +M E + A+ +A++RD SG G+ Sbjct: 127 IGCPMVTDDFVVSGTCSEQMYGMCESLWEPNMDPEHLFETISQAMLNAVDRDAVSGMGVI 186 Query: 184 LAVITKDGVK 193 + VI KD + Sbjct: 187 VHVIEKDKIT 196 >5FMG-M nrPDB Length = 240 Score = 173 bits (439), Expect = 5e-44, Method: Composition-based stats. Identities = 55/200 (27%), Positives = 93/200 (46%), Gaps = 9/200 (4%) Query: 3 VMKGTTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIV 62 + G T +GL D VILA D R SL + + K+ K+ D + +G D + + Sbjct: 34 IDNGGTVIGLTGKDYVILAADTRLSLSYSIYTRFCPKISKLTDKCIIGSSGMQSDIKTLH 93 Query: 63 RLLIAEAKLYKMRTGRNIPPLACATLLSNILHSSRMFPFLTQIIIGGYDLLEGAKLFSLD 122 LL + +L+ + A LL IL+S R FP+ I+ G D L++ D Sbjct: 94 SLLQKKIQLFVLEHSHYPDIHVIARLLCVILYSRRFFPYYAFNILAGVDENNKGVLYNYD 153 Query: 123 PLGGMNEEKTFTATGSGSPIAYGVLEAGYDR--------DMSVEEGIKLALNALKSAMER 174 +G E T + GSGS + +L+ ++ + ++ + I +A+ SA ER Sbjct: 154 SVGSYCEA-THSCVGSGSQLILPILDNRVEQKNQLIKNTNFNLGDDINFVKDAITSATER 212 Query: 175 DTFSGNGISLAVITKDGVKI 194 D ++G+ + VI K G+ + Sbjct: 213 DIYTGDKTLIYVIDKMGINV 232 >4FZC-A nrPDB Length = 250 Score = 172 bits (435), Expect = 2e-43, Method: Composition-based stats. Identities = 59/227 (25%), Positives = 100/227 (44%), Gaps = 18/227 (7%) Query: 3 VMKGTTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIV 62 V +G T++G+ + V++AT+K+ S L + K+ + I +G D + +V Sbjct: 28 VKQGVTSLGIKATNGVVIATEKK-SSSPLAMSETLSKVSLLTPDIGAVYSGMGPDYRVLV 86 Query: 63 RLLIAEAKL-YKMRTGRNIP----PLACATLLSNILHSSRMFPFLTQIIIGGYDLLEGAK 117 A YK G P A ++ S + PF ++I G+D G Sbjct: 87 DKSRKVAHTSYKRIYGEYPPTKLLVSEVAKIMQEATQSGGVRPFGVSLLIAGHDEFNGFS 146 Query: 118 LFSLDPLGGMNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERDTF 177 L+ +DP G K TA G GS A LE ++ ++ +E+ I +AL LK ++E + F Sbjct: 147 LYQVDPSGSYFPWKA-TAIGKGSVAAKTFLEKRWNDELELEDAIHIALLTLKESVEGE-F 204 Query: 178 SGNGISLAVITKDGVKIFEDEEIEKILDSMKAKPKKKTTKRSRRKSK 224 +G+ I LA+I +E +L P K + + S+ Sbjct: 205 NGDTIELAII---------GDENPDLL-GYTGIPTDKGPRFRKLTSQ 241 >5FMG-C nrPDB Length = 246 Score = 171 bits (434), Expect = 2e-43, Method: Composition-based stats. Identities = 63/216 (29%), Positives = 99/216 (45%), Gaps = 9/216 (4%) Query: 3 VMKGTTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIV 62 + + T+GLI D VIL DK + +K+YKID +I +AG DA ++ Sbjct: 28 INNASITIGLITKDGVILGADKVFISKLIDKANNYEKIYKIDKHIFCGVAGLNADANILI 87 Query: 63 RLLIAEAKLYKMRTGRNIPPLACATLLSNILHSSRMF----PFLTQIIIGGYDLLEGAKL 118 A+ Y P + +I S + P+ +IGGYD +G +L Sbjct: 88 NQSRLYAQRYLYNYNEVQPVSQLVVQICDIKQSYTQYGGLRPYGVSFLIGGYDTKDGYQL 147 Query: 119 FSLDPLGGMNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERDTFS 178 + DP G + TA G+ + A VL+ + DM++EEG+ LAL L + + + Sbjct: 148 YHTDPSGNYSGWFA-TAIGTNNLTASSVLKQEWKNDMTLEEGLLLALKTLAKSTDTEIPK 206 Query: 179 GNGISLAVIT-KDG---VKIFEDEEIEKILDSMKAK 210 I LA +T KDG K ++EIE+++ K Sbjct: 207 SEKIELAYLTNKDGEVYQKYLTEKEIEELIKLYTQK 242 >6EPF-6 nrPDB Length = 240 Score = 170 bits (430), Expect = 7e-43, Method: Composition-based stats. Identities = 54/198 (27%), Positives = 101/198 (51%), Gaps = 10/198 (5%) Query: 5 KGTTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIVRL 64 G T + + +D I+A+D R S G + +++ K YK+ D + +G GD + ++ Sbjct: 35 NGGTVLAIAGEDFSIVASDTRLSEGFSIHTRDSPKCYKLTDKTVIGCSGFHGDCLTLTKI 94 Query: 65 LIAEAKLYKMRTGRNIPPLACATLLSNILHSSRMFPFLTQIIIGGYDLLEGAKLFSLDPL 124 + A K+YK + + A A +LS IL+S R FP+ II G D ++S DP+ Sbjct: 95 IEARLKMYKHSNNKAMTTGAIAAMLSTILYSRRFFPYYVYNIIEGLDEEGKGAVYSFDPV 154 Query: 125 GGMNEEKTFTATGSGSPIAYGVLEAGY---------DRDMSVEEGIKLALNALKSAMERD 175 G + +F A GS S + +L+ ++++ ++L + SA ERD Sbjct: 155 GSY-QRDSFKAGGSASAMLQPLLDNQVGFKNMQNVEHVPLTLDRAMRLVKDVFISAAERD 213 Query: 176 TFSGNGISLAVITKDGVK 193 ++G+ + + ++TK+G++ Sbjct: 214 VYTGDALRICIVTKEGIR 231 >2KU2-A nrPDB Length = 237 Score = 169 bits (428), Expect = 1e-42, Method: Composition-based stats. Identities = 60/207 (28%), Positives = 102/207 (49%), Gaps = 9/207 (4%) Query: 3 VMKGTTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIV 62 V KG+T +G+ + V+L +DK+ L+ +K+ IDDY+A +G V DA+ +V Sbjct: 35 VKKGSTALGMKFANGVLLISDKKV-RSRLIEQNSIEKIQLIDDYVAAVTSGLVADARVLV 93 Query: 63 RLLIAEAKLYKMRTGRNIPPLACATLLSNILHSSRMF----PFLTQIIIGGYDLLEGAKL 118 A+ K+ G + +++ + + P+ +I G D + G +L Sbjct: 94 DFARISAQQEKVTYGSLVNIENLVKRVADQMQQYTQYGGVRPYGVSLIFAGIDQI-GPRL 152 Query: 119 FSLDPLGGMNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERDTFS 178 F DP G +NE K TA GSG LE Y ++ +E + L + ALKS++E + Sbjct: 153 FDCDPAGTINEYKA-TAIGSGKDAVVSFLEREYKENLPEKEAVTLGIKALKSSLE-EGEE 210 Query: 179 GNGISLAVIT-KDGVKIFEDEEIEKIL 204 +A IT + +I++ EE++K L Sbjct: 211 LKAPEIASITVGNKYRIYDQEEVKKFL 237 >5FGE-J nrPDB Length = 198 Score = 164 bits (416), Expect = 3e-41, Method: Composition-based stats. Identities = 49/194 (25%), Positives = 88/194 (45%), Gaps = 4/194 (2%) Query: 9 TVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIVRLLIAE 68 +G+ D+VILA+ K + G V K ++ + M+ AG GD + A Sbjct: 4 ILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQAN 63 Query: 69 AKLYKMRTGRNIPPLACATLLSNILHS--SRMFPFLTQIIIGGYD-LLEGAKLFSLDPLG 125 +LY +R + P A ++ + L P+ ++IGGYD +L+ +D LG Sbjct: 64 IQLYSIREDYELSPQAVSSFVRQELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQIDYLG 123 Query: 126 GMNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERDTFSGNGISLA 185 E + A G + +L+ Y DM+ EEG+ L ++ +R G+ + Sbjct: 124 TKVE-LPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQELEKRMPMDFKGVIVK 182 Query: 186 VITKDGVKIFEDEE 199 ++ KDG++ +D + Sbjct: 183 IVDKDGIRQVDDFQ 196 >3WXR-K nrPDB Length = 238 Score = 164 bits (415), Expect = 3e-41, Method: Composition-based stats. Identities = 49/194 (25%), Positives = 88/194 (45%), Gaps = 4/194 (2%) Query: 9 TVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIVRLLIAE 68 +G+ D+VILA+ K + G V K ++ + M+ AG GD + A Sbjct: 4 ILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQAN 63 Query: 69 AKLYKMRTGRNIPPLACATLLSNILHS--SRMFPFLTQIIIGGYD-LLEGAKLFSLDPLG 125 +LY +R + P A ++ + L P+ ++IGGYD +L+ +D LG Sbjct: 64 IQLYSIREDYELSPQAVSSFVRQELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQIDYLG 123 Query: 126 GMNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERDTFSGNGISLA 185 E + A G + +L+ Y DM+ EEG+ L ++ +R G+ + Sbjct: 124 TKVE-LPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQELEKRMPMDFKGVIVK 182 Query: 186 VITKDGVKIFEDEE 199 ++ KDG++ +D + Sbjct: 183 IVDKDGIRQVDDFQ 196 >3NZW-L nrPDB Length = 241 Score = 163 bits (414), Expect = 4e-41, Method: Composition-based stats. Identities = 53/207 (25%), Positives = 91/207 (43%), Gaps = 19/207 (9%) Query: 5 KGTTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIVRL 64 G T +G+ +D +LA D R + + K++ D I M+ G D A+V+ Sbjct: 27 NGGTILGIAGEDFAVLAGDTRNITDYSINSRYEPKVFDCGDNIVMSANGFAADGDALVKR 86 Query: 65 LIAEAKLYKM-RTGRNIPPLACATLLSNILHSSRMFPFLTQIIIGGYDLLEGAKLFSLDP 123 K Y + + + A + ++L+ R FP+ II G D ++S DP Sbjct: 87 FKNSVKWYHFDHNDKKLSINSAARNIQHLLYGKRFFPYYVHTIIAGLDEDGKGAVYSFDP 146 Query: 124 LGGMNEEKTFTATGSGSPIAYGVLEAGYD-----------------RDMSVEEGIKLALN 166 +G E+ A G+ + + L+ + + +SVEE IKL + Sbjct: 147 VGSYEREQC-RAGGAAASLIMPFLDNQVNFKNQYEPGTNGKVKKPLKYLSVEEVIKLVRD 205 Query: 167 ALKSAMERDTFSGNGISLAVITKDGVK 193 + SA ER G+G+ + ++TKDGV+ Sbjct: 206 SFTSATERHIQVGDGLEILIVTKDGVR 232 >5FMG-N nrPDB Length = 265 Score = 163 bits (412), Expect = 7e-41, Method: Composition-based stats. Identities = 53/243 (21%), Positives = 92/243 (37%), Gaps = 39/243 (16%) Query: 3 VMKGTTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIV 62 V+ GT+ + + +++A D++AS G+ + ++++KI++ M +G + DAQ + Sbjct: 6 VVTGTSVIAIKYKHGIMIAADRKASYGSYAKFQNVERIFKINNKTVMGFSGELADAQYLH 65 Query: 63 RLL-IAEAKL--YKMRTGRNIPPLACATLLSNILH--SSRMFPFLTQIIIGGY------- 110 LL K R P + +S + + +R+ P III G Sbjct: 66 ELLTRKNINNLSEKKRKEDMYTPQHYHSYVSRVFYVRKNRIDPLFNNIIIAGINSQKYDN 125 Query: 111 --------------DLLEGAK------------LF-SLDPLGGMNEEKTFTATGSGSPIA 143 D K L+ + G N + TG A Sbjct: 126 NDDNVLLYTNKNNDDEQNEYKNNEEYKEIHKDDLYIGFVDMHGTNFCDDYITTGYARYFA 185 Query: 144 YGVLEAGYDRDMSVEEGIKLALNALKSAMERDTFSGNGISLAVITKDGVKIFEDEEIEKI 203 +L Y +M+ EE L L+ RD S N I + +T GV+ E + + Sbjct: 186 LTLLRDHYKDNMTEEEARILINECLRILYFRDATSSNFIQIVKVTSKGVEYEEPYILPCV 245 Query: 204 LDS 206 L+S Sbjct: 246 LNS 248 >5GJQ-g nrPDB Length = 264 Score = 161 bits (409), Expect = 1e-40, Method: Composition-based stats. Identities = 47/204 (23%), Positives = 92/204 (45%), Gaps = 7/204 (3%) Query: 3 VMKGTTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIV 62 ++ GT+ +G+ + V++A D S G+L + ++ ++++ + +G D Q + Sbjct: 50 MVTGTSVLGVKFEGGVVIAADMLGSYGSLARFRNISRIMRVNNSTMLGASGDYADFQYLK 109 Query: 63 RLLIAEAKLYKMR-TGRNIPPLACATLLSNILHSSR--MFPFLTQIIIGGYDLLEGAKLF 119 ++L ++ G + P A + L+ ++S R M P ++IGGY +G Sbjct: 110 QVLGQMVIDEELLGDGHSYSPRAIHSWLTRAMYSRRSKMNPLWNTMVIGGY--ADGESFL 167 Query: 120 SLDPLGGMNEEKTFTATGSGSPIAYGVLEAGYDRD--MSVEEGIKLALNALKSAMERDTF 177 + G+ E ATG G+ +A +L ++ +S E L ++ RD Sbjct: 168 GYVDMLGVAYEAPSLATGYGAYLAQPLLREVLEKQPVLSQTEARDLVERCMRVLYYRDAR 227 Query: 178 SGNGISLAVITKDGVKIFEDEEIE 201 S N +A +T+ GV+I E Sbjct: 228 SYNRFQIATVTEKGVEIEGPLSTE 251 >6EPE-7 nrPDB Length = 263 Score = 161 bits (408), Expect = 2e-40, Method: Composition-based stats. Identities = 48/200 (24%), Positives = 90/200 (45%), Gaps = 7/200 (3%) Query: 3 VMKGTTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIV 62 ++ GT+ +G+ D V++A D S G+L + ++ +++D + +G D Q + Sbjct: 49 MVTGTSVLGVKFDCGVVIAADMLGSYGSLARFRNISRIMRVNDSTMLGASGDYADFQYLK 108 Query: 63 RLLIAEAKLYKM-RTGRNIPPLACATLLSNILHSSR--MFPFLTQIIIGGYDLLEGAKLF 119 ++L ++ G + P A + L+ ++S R M P +IGGY G Sbjct: 109 QVLGQMVIDEELFGDGHSYSPRAIHSWLTRAMYSRRSKMNPLWNTKVIGGY--AGGESFL 166 Query: 120 SLDPLGGMNEEKTFTATGSGSPIAYGVLEAGYDRD--MSVEEGIKLALNALKSAMERDTF 177 + G+ E ATG G+ +A +L ++ +S E +L ++ RD Sbjct: 167 GYVDMLGVAYEAPSLATGYGAYLAQPLLREVLEKQPVLSQTEARELVERCMRVLYYRDAR 226 Query: 178 SGNGISLAVITKDGVKIFED 197 S N +A +T+ GV+I Sbjct: 227 SYNRFQVATVTEKGVEIEGP 246 >1IRU-A nrPDB Length = 246 Score = 160 bits (405), Expect = 5e-40, Method: Composition-based stats. Identities = 49/213 (23%), Positives = 92/213 (43%), Gaps = 11/213 (5%) Query: 6 GTTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIVRLL 65 G T+V + D ++ T K+ L+ L+KI + I + G D+++ V+ Sbjct: 36 GLTSVAVRGKDCAVIVTQKKVP-DKLLDSSTVTHLFKITENIGCVMTGMTADSRSQVQRA 94 Query: 66 IAEAKLYKMRTGRNIPPLACATLLSNILHSSR----MFPFLTQIIIGGYDLLEGAKLFSL 121 EA +K + G IP +++I M P +I+ G D +G +++ Sbjct: 95 RYEAANWKYKYGYEIPVDMLCKRIADISQVYTQNAEMRPLGCCMILIGIDEEQGPQVYKC 154 Query: 122 DPLGGMNEEKTFTATGSGSPIAYGVLEAGYDR--DMSVEEGIKLALNALKSAMERDTFSG 179 DP G K TA G + LE + D + E+ ++ A+ L + + D F Sbjct: 155 DPAGYYCGFKA-TAAGVKQTESTSFLEKKVKKKFDWTFEQTVETAITCLSTVLSID-FKP 212 Query: 180 NGISLAVITKDG--VKIFEDEEIEKILDSMKAK 210 + I + V+T + +I + EI+ L ++ + Sbjct: 213 SEIEVGVVTVENPKFRILTEAEIDAHLVALAER 245 >5LF6-M nrPDB Length = 219 Score = 160 bits (404), Expect = 6e-40, Method: Composition-based stats. Identities = 47/204 (23%), Positives = 92/204 (45%), Gaps = 7/204 (3%) Query: 3 VMKGTTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIV 62 ++ GT+ +G+ + V++A D S G+L + ++ ++++ + +G D Q + Sbjct: 5 MVTGTSVLGVKFEGGVVIAADMLGSYGSLARFRNISRIMRVNNSTMLGASGDYADFQYLK 64 Query: 63 RLLIAEAKLYKMR-TGRNIPPLACATLLSNILHSSR--MFPFLTQIIIGGYDLLEGAKLF 119 ++L ++ G + P A + L+ ++S R M P ++IGGY +G Sbjct: 65 QVLGQMVIDEELLGDGHSYSPRAIHSWLTRAMYSRRSKMNPLWNTMVIGGY--ADGESFL 122 Query: 120 SLDPLGGMNEEKTFTATGSGSPIAYGVLEAGYDRD--MSVEEGIKLALNALKSAMERDTF 177 + G+ E ATG G+ +A +L ++ +S E L ++ RD Sbjct: 123 GYVDMLGVAYEAPSLATGYGAYLAQPLLREVLEKQPVLSQTEARDLVERCMRVLYYRDAR 182 Query: 178 SGNGISLAVITKDGVKIFEDEEIE 201 S N +A +T+ GV+I E Sbjct: 183 SYNRFQIATVTEKGVEIEGPLSTE 206 >6FVW-g nrPDB Length = 245 Score = 156 bits (395), Expect = 6e-39, Method: Composition-based stats. Identities = 54/190 (28%), Positives = 82/190 (43%), Gaps = 10/190 (5%) Query: 3 VMKGTTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIV 62 V GTT++G+ C+D V+ A +K + LV K K+ +D +I +G + D + +V Sbjct: 28 VENGTTSIGIKCNDGVVFAVEKLITSKLLVPQKNV-KIQVVDRHIGCVYSGLIPDGRHLV 86 Query: 63 RLLIAEAKLYKMRTGRNIPPLACATLLSNILHSSRMF----PFLTQIIIGGYDLLEGAKL 118 EA +K IP A A L + + ++ PF I GG D GA L Sbjct: 87 NRGREEAASFKKLYKTPIPIPAFADRLGQYVQAHTLYNSVRPFGVSTIFGGVD-KNGAHL 145 Query: 119 FSLDPLGGMNEEKTFTATGSGSPIAYGVLEAGYD---RDMSVEEGIKLALNALKSAMERD 175 + L+P G K ATG G A LE D +S E +K A + A E + Sbjct: 146 YMLEPSGSYWGYKG-AATGKGRQSAKAELEKLVDHHPEGLSAREAVKQAAKIIYLAHEDN 204 Query: 176 TFSGNGISLA 185 + ++ Sbjct: 205 KEKDFELEIS 214 >5FGG-F nrPDB Length = 288 Score = 156 bits (395), Expect = 6e-39, Method: Composition-based stats. Identities = 54/190 (28%), Positives = 82/190 (43%), Gaps = 10/190 (5%) Query: 3 VMKGTTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIV 62 V GTT++G+ C+D V+ A +K + LV K K+ +D +I +G + D + +V Sbjct: 31 VENGTTSIGIKCNDGVVFAVEKLITSKLLVPQKNV-KIQVVDRHIGCVYSGLIPDGRHLV 89 Query: 63 RLLIAEAKLYKMRTGRNIPPLACATLLSNILHSSRMF----PFLTQIIIGGYDLLEGAKL 118 EA +K IP A A L + + ++ PF I GG D GA L Sbjct: 90 NRGREEAASFKKLYKTPIPIPAFADRLGQYVQAHTLYNSVRPFGVSTIFGGVD-KNGAHL 148 Query: 119 FSLDPLGGMNEEKTFTATGSGSPIAYGVLEAGYD---RDMSVEEGIKLALNALKSAMERD 175 + L+P G K ATG G A LE D +S E +K A + A E + Sbjct: 149 YMLEPSGSYWGYKG-AATGKGRQSAKAELEKLVDHHPEGLSAREAVKQAAKIIYLAHEDN 207 Query: 176 TFSGNGISLA 185 + ++ Sbjct: 208 KEKDFELEIS 217 >5FMG-F nrPDB Length = 254 Score = 155 bits (392), Expect = 1e-38, Method: Composition-based stats. Identities = 46/224 (20%), Positives = 96/224 (42%), Gaps = 14/224 (6%) Query: 3 VMKGTTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIV 62 + +GT V + D V+++ K+ +K++KIDDYI ++++G DA+ + Sbjct: 29 IKQGTCAVAIKSKDYVVVSGLKKCISKLSFPQ---EKIFKIDDYIGISMSGITSDAKVLT 85 Query: 63 RLLIAEAKLYKMRTGRNIPPLACATLLSNILHSSRM----FPFLTQIIIGGYDLLEGAKL 118 + + E +K NI + +++ + F ++I Y + Sbjct: 86 KFMQNECLSHKFLYNENINIESLVRSVADKYQKNTQKSSKRAFGVGLMIAAY--HNEPCI 143 Query: 119 FSLDPLGGMNEEKTFTATGSGSPIAYGVLEAGYD--RDMSVEEGIKLALNALKSAMERDT 176 F P G E + G+ S + LE + S+EE I L ALK ++ ++ Sbjct: 144 FETRPNGSYFEYDALS-FGARSHASKTYLEKNLHLFEECSLEELILHCLKALKCSLSSES 202 Query: 177 -FSGNGISLAVITKDG-VKIFEDEEIEKILDSMKAKPKKKTTKR 218 + + +LAV+ K+ + ++E+ L +K +++ + Sbjct: 203 ELTISNTALAVVGKNHPWQEISSLQLEEYLSKVKMDAEQEQVEE 246 >5FMG-B nrPDB Length = 235 Score = 155 bits (392), Expect = 2e-38, Method: Composition-based stats. Identities = 51/211 (24%), Positives = 93/211 (44%), Gaps = 9/211 (4%) Query: 3 VMKGTTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIV 62 V + +G+ + VI+AT+K+ S L+ + K+ +I ++I + AG GD + ++ Sbjct: 29 VSSSSPALGIRAKNGVIIATEKK-SPNELIEENSIFKIQQISEHIGIVYAGMPGDFRVLL 87 Query: 63 RLLIAEAKLYKMRTGRNIPPLA----CATLLSNILHSSRMFPFLTQIIIGGYDLLEGAKL 118 + EA Y ++ G I A+++ + + PF ++I G D+ G L Sbjct: 88 KRARKEAIRYSLQYGSEILVKELVKIIASIVQEFTQTGGVRPFGLSLLICGVDV-YGYHL 146 Query: 119 FSLDPLGGMNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERDTFS 178 + +DP G T G LE Y++D+ +E+ I A+ LK + E + Sbjct: 147 YQIDPSGCYFNWMA-TCVGKDYQNNMSFLEKRYNKDIEIEDAIHTAILTLKESYEG-VLN 204 Query: 179 GNGISLAV-ITKDGVKIFEDEEIEKILDSMK 208 I + V KI EI+ L ++ Sbjct: 205 EKNIEIGVAYDNKPFKILTQNEIKDYLIEIE 235 >5FMG-J nrPDB Length = 218 Score = 155 bits (391), Expect = 2e-38, Method: Composition-based stats. Identities = 47/201 (23%), Positives = 87/201 (43%), Gaps = 13/201 (6%) Query: 5 KGTTTVGLICDDAVILATDKRASLGNLV-ADKEAKKLYKIDDYIAMTIAGSVGDAQAIVR 63 G +G+ + V +A D R + K++K+++ + + ++G D Q + Sbjct: 8 NGGCVLGMSGSNCVAIACDLRLGANTFTTVSTKFSKIFKMNNNVYVGLSGLATDIQTLYE 67 Query: 64 LLIAEAKLYKMRTGRNIPPLACATLLSNILHSSRMFPFLTQIIIGGYDLL---------- 113 +L LY++R + A +LS+IL+S+R P+ I+ G+ L Sbjct: 68 ILRYRVNLYEVRQDAEMDVECFANMLSSILYSNRFSPYFVNPIVVGFKLKHYVDEEGEKK 127 Query: 114 --EGAKLFSLDPLGGMNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSA 171 L + D +G E + F G S +G+ E+ Y +D + L SA Sbjct: 128 VNYEPYLTAYDLIGAKCETRDFVVNGVTSEQLFGMCESLYVKDQDENGLFETISQCLLSA 187 Query: 172 MERDTFSGNGISLAVITKDGV 192 ++RD SG G + V+T + + Sbjct: 188 LDRDCISGWGAEVLVLTPEKI 208 >3NZW-E nrPDB Length = 234 Score = 153 bits (387), Expect = 5e-38, Method: Composition-based stats. Identities = 52/211 (24%), Positives = 94/211 (44%), Gaps = 14/211 (6%) Query: 3 VMKGTTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIV 62 + +G+ TVGL + +L KR + KK+ K D+++ +++AG DA+ + Sbjct: 29 IKQGSVTVGLRSNTHAVLVALKRNADEL---SSYQKKIIKCDEHMGLSLAGLAPDARVLS 85 Query: 63 RLLIAEAKLYKMRTGRNIPPLACATLLSNI----LHSSRMFPFLTQIIIGGYDLLEGAKL 118 L + + R + LL + S P+ ++I GYD GA L Sbjct: 86 NYLRQQCNYSSLVFNRKLAVERAGHLLCDKAQKNTQSYGGRPYGVGLLIIGYD-KSGAHL 144 Query: 119 FSLDPLGGMNEEKTFTATGSGSPIAYGVLEAGYDR----DMSVEEGIKLALNALKSAMER 174 P G + E TA G+ S A LE D D + +E IK + A+ ++ Sbjct: 145 LEFQPSGNVTELYG-TAIGARSQGAKTYLERTLDTFIKIDGNPDELIKAGVEAISQSLRD 203 Query: 175 DTFSGNGISLAVITKDG-VKIFEDEEIEKIL 204 ++ + + +S+A++ KD I++ E + K + Sbjct: 204 ESLTVDNLSIAIVGKDTPFTIYDGEAVAKYI 234 >4Y8P-I nrPDB Length = 205 Score = 149 bits (377), Expect = 7e-37, Method: Composition-based stats. Identities = 48/189 (25%), Positives = 88/189 (46%), Gaps = 2/189 (1%) Query: 5 KGTTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIVRL 64 G V + D V +A D R +L + +K++ ++ + I G D + + Sbjct: 8 NGGIVVAMTGKDCVAIACDLRLGSQSLGVSNKFEKIFHYG-HVFLGITGLATDVTTLNEM 66 Query: 65 LIAEAKLYKMRTGRNIPPLACATLLSNILHSSRMFPFLTQIIIGGYDLLEG-AKLFSLDP 123 + LYK++ R I P L+S+ L+ R P+ ++ G + G + D Sbjct: 67 FRYKTNLYKLKEERAIEPETFTQLVSSSLYERRFGPYFVGPVVAGINSKSGKPFIAGFDL 126 Query: 124 LGGMNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERDTFSGNGIS 183 +G ++E K F +G+ S +G+ E+ Y+ ++ E+ + AL +A +RD SG G Sbjct: 127 IGCIDEAKDFIVSGTASDQLFGMCESLYEPNLEPEDLFETISQALLNAADRDALSGWGAV 186 Query: 184 LAVITKDGV 192 + +I KD V Sbjct: 187 VYIIKKDEV 195 >5FMG-H nrPDB Length = 252 Score = 149 bits (377), Expect = 9e-37, Method: Composition-based stats. Identities = 54/243 (22%), Positives = 102/243 (41%), Gaps = 54/243 (22%) Query: 7 TTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIVRLL- 65 TT +G+I D+ V+LA D R S G +++K ++K+ +I++ + + +G+ +Q I+ ++ Sbjct: 1 TTIIGIIYDNGVMLACDSRTSSGTFISNKCSRKINRINENLYVCRSGASAHSQKIIEIIK 60 Query: 66 ----------IAEAKLYK------------------------------------------ 73 + + ++ Sbjct: 61 HYCVSMKNENRKKGRFHEGETIYDETTYDEEIDIDSINYLDYNNNNDNNLVTKNKYFYED 120 Query: 74 MRTGRNIPPLACATLLSNILHSSRMFPFLTQIIIGGYDLLEGAKLFSLDPLGGMNEEKTF 133 N A + I++++ F +I GGYD ++ +L++++ G + E+ F Sbjct: 121 KFNDYNPLVENVAHITKKIIYTNNNF-LSCALIFGGYDKIKKQQLYAVNLNGSIIEKHDF 179 Query: 134 TATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERDTFSGNGISLAVITKDGVK 193 +GSGS L+ Y + M+ +E L LN +K AM D SG I + ITK V+ Sbjct: 180 AVSGSGSIYIQSYLQDKYKKFMTKKECFNLILNCVKYAMHNDNSSGGLIRIVNITKSFVE 239 Query: 194 IFE 196 F Sbjct: 240 EFT 242 >5LF3-J nrPDB Length = 201 Score = 148 bits (374), Expect = 2e-36, Method: Composition-based stats. Identities = 49/197 (24%), Positives = 91/197 (46%), Gaps = 7/197 (3%) Query: 10 VGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIVRLLIAEA 69 +G+ D V++A+D+ A+ + + K++K+ + I + G GD + Sbjct: 5 IGIQGPDYVLVASDRVAASNIVQMKDDHDKMFKMSEKILLLCVGEAGDTVQFAEYIQKNV 64 Query: 70 KLYKMRTGRNIPPLACATL----LSNILHSSRMFPFLTQIIIGGYDLLEGAKLFSLDPLG 125 +LYKMR G + P A A L++ L S P+ +++ GYD EG L+ +D L Sbjct: 65 QLYKMRNGYELSPTAAANFTRRNLADCLRSRT--PYHVNLLLAGYDEHEGPALYYMDYL- 121 Query: 126 GMNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERDTFSGNGISLA 185 + F A G G+ + +L+ Y +S E ++L L+ +R + S+ Sbjct: 122 AALAKAPFAAHGYGAFLTLSILDRYYTPTISRERAVELLRKCLEELQKRFILNLPTFSVR 181 Query: 186 VITKDGVKIFEDEEIEK 202 +I K+G+ ++ K Sbjct: 182 IIDKNGIHDLDNISFPK 198 >1Q5R-H nrPDB Length = 294 Score = 145 bits (367), Expect = 1e-35, Method: Composition-based stats. Identities = 57/185 (30%), Positives = 91/185 (49%), Gaps = 9/185 (4%) Query: 5 KGTTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIVRL 64 GTT V L V+LA D+RA+ GNL+A ++ + +Y D+Y A IAG+ G A +VRL Sbjct: 64 HGTTIVALTYKGGVLLAGDRRATQGNLIASRDVEAVYVTDEYSAAGIAGTAGIAIELVRL 123 Query: 65 LIAEAKLYKMRTGRNIPPLACATLLSNILHSS---RMFPFLTQIIIGGY-----DLLEGA 116 E + Y+ G + A L++++ + M ++ GY D Sbjct: 124 FAVELEHYEKIEGVPLTFDGKANRLASMVRGNLGAAMQGLAVVPLLVGYDLDADDESRAG 183 Query: 117 KLFSLDPLGGMNEEKT-FTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERD 175 ++ S D +GG EE+ + A GSGS A L+ Y D E ++ A+ +L A + D Sbjct: 184 RIVSYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDSDEETALRAAIESLYDAADDD 243 Query: 176 TFSGN 180 + +G Sbjct: 244 SATGG 248 >1Q5Q-H nrPDB Length = 235 Score = 142 bits (359), Expect = 1e-34, Method: Composition-based stats. Identities = 57/183 (31%), Positives = 91/183 (49%), Gaps = 9/183 (4%) Query: 7 TTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIVRLLI 66 TT V L V+LA D+RA+ GNL+A ++ +K+Y D+Y A IAG+ G A +VRL Sbjct: 1 TTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAGTAGIAIELVRLFA 60 Query: 67 AEAKLYKMRTGRNIPPLACATLLSNILHSS---RMFPFLTQIIIGGY-----DLLEGAKL 118 E + Y+ G + A L++++ + M ++ GY D ++ Sbjct: 61 VELEHYEKIEGVPLTFDGKANRLASMVRGNLGAAMQGLAVVPLLVGYDLDADDESRAGRI 120 Query: 119 FSLDPLGGMNEEKT-FTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERDTF 177 S D +GG EE+ + A GSGS A L+ Y D E ++ A+ +L A + D+ Sbjct: 121 VSYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDSDEETALRAAIESLYDAADDDSA 180 Query: 178 SGN 180 +G Sbjct: 181 TGG 183 >6GOP-M nrPDB Length = 246 Score = 142 bits (358), Expect = 1e-34, Method: Composition-based stats. Identities = 54/229 (23%), Positives = 96/229 (41%), Gaps = 14/229 (6%) Query: 3 VMKGTTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIV 62 ++ GT+ + + D+ VI+A D S G+L+ ++L + D + I+G + D Q I Sbjct: 18 IVTGTSVISMKYDNGVIIAADNLGSYGSLLRFNGVERLIPVGDNTVVGISGDISDMQHIE 77 Query: 63 RLLI--AEAKLYKMRT---GRNIPPLACATLLSNILHSSR--MFPFLTQIIIGGYDLLEG 115 RLL Y + P L+ +++ R M P II+ G G Sbjct: 78 RLLKDLVTENAYDNPLADAEEALEPSYIFEYLATVMYQRRSKMNPLWNAIIVAGV-QSNG 136 Query: 116 AKLFSLDPLGGMNEEKTFTATGSGSPIAYGVLEAGYD-----RDMSVEEGIKLALNALKS 170 + L G+ ATG G+ +A +L D +V+ + +NA++ Sbjct: 137 DQFLRYVNLLGVTYSSPTLATGFGAHMANPLLRKVVDRESDIPKTTVQVAEEAIVNAMRV 196 Query: 171 AMERDTFSGNGISLAVITKD-GVKIFEDEEIEKILDSMKAKPKKKTTKR 218 RD S SLA+I K+ G+ ++ ++E + K T++ Sbjct: 197 LYYRDARSSRNFSLAIIDKNTGLTFKKNLQVENMKWDFAKDIKGYGTQK 245 >6EPD-G nrPDB Length = 255 Score = 140 bits (352), Expect = 6e-34, Method: Composition-based stats. Identities = 47/220 (21%), Positives = 96/220 (43%), Gaps = 8/220 (3%) Query: 3 VMKGTTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIV 62 V +T +G+ C D V+ +K L L + K+L+ +D ++ M +AG + DA+++ Sbjct: 31 VENSSTAIGIRCKDGVVFGVEKLV-LSKLYEEGSNKRLFNVDRHVGMAVAGLLADARSLA 89 Query: 63 RLLIAEAKLYKMRTGRNIPPLACATLLSNILHSSRMF----PFLTQIIIGGYDLLEGAKL 118 + EA ++ G NIP A ++ +H+ ++ PF ++G Y + +GA+L Sbjct: 90 DIAREEASNFRSNFGYNIPLKHLADRVAMYVHAYTLYSAVRPFGCSFMLGSYSVNDGAQL 149 Query: 119 FSLDPLGGMNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERDTFS 178 + +DP G A G A +E ++M+ + +K + + Sbjct: 150 YMIDPSGVSYGYWGC-AIGKARQAAKTEIEKLQMKEMTCRDVVKEVAKIIYIVHDEVKDK 208 Query: 179 GNGISLAVITKDGVKIFEDEEIEKILDSMKAKPKKKTTKR 218 + L+ + + + E + K + K K++ K Sbjct: 209 AFELELSWVGE--LTKGRHEIVPKDVREEAEKYAKESLKE 246 >2JAY-A nrPDB Length = 291 Score = 137 bits (345), Expect = 4e-33, Method: Composition-based stats. Identities = 54/221 (24%), Positives = 96/221 (43%), Gaps = 16/221 (7%) Query: 5 KGTTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIVRL 64 GTT V L V++A D+R++ GN+++ ++ +K+Y DDY A IAG+ A RL Sbjct: 56 HGTTIVALKYPGGVVMAGDRRSTQGNMISGRDVRKVYITDDYTATGIAGTAAVAVEFARL 115 Query: 65 LIAEAKLYKMRTGRNIPPLACATLLSNILHSSRMFPFL--------TQIIIGGYDLLEGA 116 E + Y+ G + L+ ++ + I D Sbjct: 116 YAVELEHYEKLEGVPLTFAGKINRLAIMVRGNLAAAMQGLLALPLLAGYDIHASDPQSAG 175 Query: 117 KLFSLDPLGGMN-EEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERD 175 ++ S D GG N EE+ + A GSGS A ++ Y + + G+++A+ AL A + D Sbjct: 176 RIVSFDAAGGWNIEEEGYQAVGSGSLFAKSSMKKLYSQVTDGDSGLRVAVEALYDAADDD 235 Query: 176 TFSGNGISL-------AVITKDGVKIFEDEEIEKILDSMKA 209 + +G + +I DG + I ++ ++ Sbjct: 236 SATGGPDLVRGIFPTAVIIDADGAVDVPESRIAELARAIIE 276 >5LZP-A nrPDB Length = 242 Score = 128 bits (322), Expect = 2e-30, Method: Composition-based stats. Identities = 52/218 (23%), Positives = 94/218 (43%), Gaps = 16/218 (7%) Query: 8 TTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIVRLLIA 67 T V L V++A D+R++ GN+++ ++ +K+Y DDY A IAG+ A RL Sbjct: 2 TIVALKYPGGVVMAGDRRSTQGNMISGRDVRKVYITDDYTATGIAGTAAVAVEFARLYAV 61 Query: 68 EAKLYKMRTGRNIPPLACATLLSNILHSSRMFPFL--------TQIIIGGYDLLEGAKLF 119 E + Y+ G + L+ ++ + I D ++ Sbjct: 62 ELEHYEKLEGVPLTFAGKINRLAIMVRGNLAAAMQGLLALPLLAGYDIHASDPQSAGRIV 121 Query: 120 SLDPLGGMN-EEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERDTFS 178 S D GG N EE+ + A GSGS A ++ Y + + G+++A+ AL A + D+ + Sbjct: 122 SFDAAGGWNIEEEGYQAVGSGSLFAKSSMKKLYSQVTDGDSGLRVAVEALYDAADDDSAT 181 Query: 179 GNGISL-------AVITKDGVKIFEDEEIEKILDSMKA 209 G + +I DG + I ++ ++ Sbjct: 182 GGPDLVRGIFPTAVIIDADGAVDVPESRIAELARAIIE 219 >5FMG-G nrPDB Length = 252 Score = 121 bits (304), Expect = 2e-28, Method: Composition-based stats. Identities = 36/186 (19%), Positives = 73/186 (39%), Gaps = 8/186 (4%) Query: 3 VMKGTTTVGLICDDAVILAT-DKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAI 61 + T + L C D +I + ++ ++Y +++ I +T +G GDA+ I Sbjct: 31 INNNNTALCLECKDGIICCCINSNMDKNKMIKKNSYNRIYHVNNNIIITYSGFDGDARNI 90 Query: 62 VRLLIAEAKLYKMRTGRNIPPLACATLLSNILHSSR----MFPFLTQIIIGGYDLLEGAK 117 + +EA Y NIP +S +H+ M PF III ++ + Sbjct: 91 IDRARSEANTYYYNFHTNIPLHILVNRISLYIHAYTLYWHMRPFAASIIISSFNEKDKGD 150 Query: 118 LFSLDPLGGMNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERDTF 177 ++ ++P G + G + +E +D++V + I+ + D Sbjct: 151 IYCIEPNGACYKYSGI-VIGKNKEMFKTEIEKKDYKDINVRDAIEDIYKFI--LTSDDHM 207 Query: 178 SGNGIS 183 + N + Sbjct: 208 NKNNLQ 213 >5LOY-A nrPDB Length = 240 Score = 118 bits (296), Expect = 2e-27, Method: Composition-based stats. Identities = 48/203 (23%), Positives = 84/203 (41%), Gaps = 15/203 (7%) Query: 7 TTTVGLICDDAVILATDKRASLG-NLVADKEAKKLYKI--DDYIAMTIAGSVGDAQAIVR 63 T VG+ D+ ++ A+D R + G + ++ ++++ + I + AG++ QA++ Sbjct: 1 TYCVGIRLDEGLVFASDSRTNAGVDNISTFRKMHVFEVPGERVIVLLTAGNLATTQAVIS 60 Query: 64 LLIAEAKLYKMRTGRNIPPLACATLLSNILH--SSRMFP--------FLTQIIIGGYDLL 113 LL K + R A L+ L +R P F I+GG Sbjct: 61 LLEERLKDPEERLLTAPSMFEAARLVGEALREVQARDAPALEADGVDFNASFILGGQIAG 120 Query: 114 EGAKLFSLDPLGGMNEEKTFTATGSGSPIAYG--VLEAGYDRDMSVEEGIKLALNALKSA 171 E +LF + P G E T YG +L+ D S+E+ K AL + S Sbjct: 121 EPPRLFLIYPAGNFIEATPDTPFFQIGETKYGKPILDRVITPDTSLEDAAKCALVSFDST 180 Query: 172 MERDTFSGNGISLAVITKDGVKI 194 M + G + L V +D +++ Sbjct: 181 MRSNLSVGLPLDLLVYERDSLRV 203 >5FMG-K nrPDB Length = 195 Score = 116 bits (290), Expect = 9e-27, Method: Composition-based stats. Identities = 40/188 (21%), Positives = 82/188 (43%), Gaps = 3/188 (1%) Query: 8 TTVGLICDDAVILATDKRASLGNL-VADKEAKKLYKIDDYIAMTIAGSVGDAQAIVRLLI 66 T +GL ++ V+LA D + + + + + K Y I + + GS+GD + Sbjct: 3 TLIGLRGNNFVVLAADTYSINSIIKLKNDDNTKFYDIHGNKCLLLGGSIGDRLQFGEFIR 62 Query: 67 AEAKLYKMRTGRNIPPLACATLL-SNILHSSRMFPFLTQIIIGGYDLLEGAKLFSLDPLG 125 LY+ + ++ + A N+ + R PF +I GYD +G +L+ D L Sbjct: 63 KNVHLYQYQNNTDMFVKSFAFFTRKNLAYYLRRNPFEVNCLIAGYDKKDGYQLYWCDYLS 122 Query: 126 GMNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERDTFSGNGISLA 185 M+ A G G+ + +L+ Y +++V+E + + + +R + L Sbjct: 123 NMDSVN-KGAHGYGAYLVSAILDKYYHENLTVDEALDIFKLCFEELKKRFLLTQINYELR 181 Query: 186 VITKDGVK 193 ++ + V+ Sbjct: 182 IMYDNKVE 189 >5FMG-A nrPDB Length = 260 Score = 104 bits (261), Expect = 2e-23, Method: Composition-based stats. Identities = 44/228 (19%), Positives = 91/228 (39%), Gaps = 23/228 (10%) Query: 4 MKGTTTVGLICDDAVILATDKR-----ASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDA 58 T+VG+ ++ ++ + K+ S L+ +Y I D I ++ G GD Sbjct: 34 NTNITSVGVKGENCAVIISQKKMATQYISQDKLLDYNNITNIYNITDEIGCSMVGMPGDC 93 Query: 59 QAIVRLLIAEAKLYKMRTGRNIPPLACATLLSNILHSSRMFPFL----TQIIIGGYDLLE 114 ++V +EA + G N+ + + + ++ +I G D Sbjct: 94 LSMVYKARSEASEFLYSNGYNVNAETLCRNICDKIQVYTQHAYMRLHACSGMIIGIDENN 153 Query: 115 GAKLFSLDPLGGMNEEKTFTATGSGSPIAYGVLEAGYDR------DMSVEEGIK----LA 164 +LF DP G + G+ + VLE ++ +++E I+ LA Sbjct: 154 KPELFKFDPSGFCAGYRA-CVIGNKEQESISVLERLLEKRKKKIQQETIDEDIRNTTILA 212 Query: 165 LNALKSAMERDTFSGNGISLAVI-TKD-GVKIFEDEEIEKILDSMKAK 210 + AL++ + D + I +A++ TK+ ++EI+ L + + Sbjct: 213 IEALQTILAFD-LKASEIEVAIVSTKNRNFTQISEKEIDNYLTYIAER 259 >5L5W-G nrPDB Length = 252 Score = 103 bits (256), Expect = 9e-23, Method: Composition-based stats. Identities = 45/213 (21%), Positives = 85/213 (39%), Gaps = 14/213 (6%) Query: 9 TVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIVRLLIAE 68 ++ + D ++ + K+ L+ ++ I I M + G + DA+ AE Sbjct: 42 SLAVRGKDCTVVISQKKVP-DKLLDPTTVSYIFCISRTIGMVVNGPIPDARNAALRAKAE 100 Query: 69 AKLYKMRTGRNIPPLACATLLSNILHSSR----MFPFLTQIIIGGYDLLEGAKLFSLDPL 124 A ++ + G ++P A ++N+ M P + D G ++ DP Sbjct: 101 AAEFRYKYGYDMPCDVLAKRMANLSQIYTQRAYMRPLGVILTFVSVDEELGPSIYKTDPA 160 Query: 125 GGMNEEKTFTATGSGSPIAYGVLEAGYDR-------DMSVEEGIKLALNALKSAMERDTF 177 G K TATG LE + + + S E+ ++ A+ + A+ + F Sbjct: 161 GYYVGYKA-TATGPKQQEITTNLENHFKKSKIDHINEESWEKVVEFAITHMIDALGTE-F 218 Query: 178 SGNGISLAVITKDGVKIFEDEEIEKILDSMKAK 210 S N + + V TKD E IE+ L ++ + Sbjct: 219 SKNDLEVGVATKDKFFTLSAENIEERLVAIAEQ 251 >5LOX-A nrPDB Length = 242 Score = 88.4 bits (218), Expect = 2e-18, Method: Composition-based stats. Identities = 35/212 (16%), Positives = 76/212 (35%), Gaps = 18/212 (8%) Query: 7 TTTVGLICDDAVILATDKRASLGNLVADKEAKKLY----KIDDYIAMTIAGSVGDAQAIV 62 T V + D ++ A+D R + G + +KL+ + + + AG++ +Q+++ Sbjct: 1 TYCVAMHLADGLVFASDSRTNAG-IDHIATFRKLFTFGTPGERLLVVQTAGNLATSQSVI 59 Query: 63 RLLIAEAKLYKMRTGRNIPPLACATLLSNILHS---------SRMFPFLTQIIIGGYDLL 113 LL + L++ + ++GG Sbjct: 60 NLLQQRIRRDGASLLNVPSVYDATALVAETTREVMARDSGNLAGNTDLSCSFMVGGQIAG 119 Query: 114 EGAKLFSLDPLGGMNEEKTFTAT---GSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKS 170 L+S+ P G + T G S +L+ D +E+ ++ AL + S Sbjct: 120 GPPALYSIYPQGNFIQATPDTPFLQLGE-SKYGKPILDRNLTFDTPLEQALRCALVSFDS 178 Query: 171 AMERDTFSGNGISLAVITKDGVKIFEDEEIEK 202 + + G + L V +D + + E + + Sbjct: 179 TIRSNLSVGMPLDLLVYHRDSLILPEGYRVTE 210 >5NYF-A nrPDB Length = 245 Score = 84.6 bits (208), Expect = 3e-17, Method: Composition-based stats. Identities = 42/215 (19%), Positives = 76/215 (35%), Gaps = 19/215 (8%) Query: 6 GTTTVGLICDDAVILATDKRASLG--NLVADKEAKKLYKIDDYIAMTIA-GSVGDAQAIV 62 GT V + ++ A D R + G N+ K+ + + + + + ++ G++ QA+V Sbjct: 2 GTYAVAFRLERGLVFAADTRTNAGVDNIAQYKKLQLWRQPGERVFVLLSAGNLAATQAVV 61 Query: 63 ----RLLIAEAKLYKMRTGRNIPPLACATLLSNILHSSR----------MFPFLTQIIIG 108 L E A ++ + + +R F T I G Sbjct: 62 SLINEHLSQETDDEVTTLFTAPNMYRAARVVGDAVREARSIDGAALEASKLGFNTNFIFG 121 Query: 109 GYDLLEGAKLFSLDPLGGMNEEKTFTATGSGSP--IAYGVLEAGYDRDMSVEEGIKLALN 166 G E +LF + P G E T +L+ DM + E KL L Sbjct: 122 GQIKGERPRLFQIYPEGNFIEATDDTPFFQIGEHKYGKPILDRVARSDMRLGEAAKLMLL 181 Query: 167 ALKSAMERDTFSGNGISLAVITKDGVKIFEDEEIE 201 + S + + G I L + +D + ++ I Sbjct: 182 SFDSTLRSNLSVGMPIDLVIYERDTFDVTREKRIS 216 >5NYW-A nrPDB Length = 251 Score = 81.5 bits (200), Expect = 2e-16, Method: Composition-based stats. Identities = 40/215 (18%), Positives = 80/215 (37%), Gaps = 21/215 (9%) Query: 7 TTTVGLICDDAVILATDKRASLGNLVADKEAKKLY----KIDDYIAMTIAGSVGDAQAIV 62 T V + + A+D R + G + +KL+ + + + AG++ Q+IV Sbjct: 1 TYCVAMRLSSGLAFASDSRTNAG-VDHISTFRKLHLFQQPGERTLVVQSAGNLATTQSIV 59 Query: 63 RLLIAEAKLYKMRTGRNI-PPLACATLLSNIL-----------HSSRMFPFLTQIIIGGY 110 LL + N+ ATLL + +S F +++GG Sbjct: 60 SLLQRRCLDPEQTNLMNVASMYEAATLLGETVREVINRDSGAQQNSHGTDFNCNLLLGGQ 119 Query: 111 DLLEGAKLFSLDPLGGMNEE---KTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNA 167 EG +LF + P G E + G S +++ D +++ ++ AL + Sbjct: 120 IKGEGLRLFHIYPQGNFIEATQDTPYFQIGE-SKYGKPIIDRVLSYDTPLDQAMQCALIS 178 Query: 168 LKSAMERDTFSGNGISLAVITKDGVKIFEDEEIEK 202 + S + + G + + + D + I + Sbjct: 179 MDSTLRSNLSVGLPLDVMIYPLDSFSTEQQYRITE 213 >4HO7-A nrPDB Length = 179 Score = 70.3 bits (171), Expect = 6e-13, Method: Composition-based stats. Identities = 40/185 (21%), Positives = 72/185 (38%), Gaps = 15/185 (8%) Query: 7 TTTVGLICDDAVILATDKRASLGNLVADKEAK-KLYKIDDYIAMTIAGSVGDAQAIVRLL 65 TT + + D V+L D++ +LG + K + KL +I+D + + AGS DA +++ L Sbjct: 1 TTILSVRKGDTVVLLGDRQVTLGERIVAKSSACKLRRINDDVVIGFAGSTADAISLMEKL 60 Query: 66 IAEAKLYKMRTGRNIPPLACATLLSNILHSSRMFPFLTQIIIGGYDLLEGAKLFSLDPLG 125 + + + A L + +I+ + +D G Sbjct: 61 ENKIGEFPNQL-----TRAAVELAKEWRTDRALRRLEASLIVC-----SAEETLEIDGQG 110 Query: 126 GMN--EEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERDTFSGNGIS 183 + E A GSG A A D+ + K+A A++ A + D FS Sbjct: 111 NVITPEADGIVAIGSGGTFAKAAARALI--DVDGYDAEKIARKAMRIATDIDVFSNEHWD 168 Query: 184 LAVIT 188 + V+ Sbjct: 169 VEVLE 173 >5JI2-A nrPDB Length = 184 Score = 60.7 bits (146), Expect = 5e-10, Method: Composition-based stats. Identities = 36/166 (21%), Positives = 62/166 (37%), Gaps = 12/166 (7%) Query: 7 TTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKI-DDYIAMTIAGSVGDAQAIVRLL 65 TT V + + V++A D +A+LGN V KK+ ++ +D + AG DA + L Sbjct: 2 TTIVSVRRNGHVVIAGDGQATLGNTVMKGNVKKVRRLYNDKVIAGFAGGTADAFTLFELF 61 Query: 66 IAEAKLYKMRTGRNIPPLACATLLSNILHSSRMFPFLTQIIIGGYDLLEGAKLFSLDPLG 125 + ++++ A L + + + + E A L Sbjct: 62 ERKLEMHQGHL-----VKAAVELAKDWRTDRMLRKLEALLAVA----DETASLIITGNGD 112 Query: 126 GMNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSA 171 + E A GSG P A A + + ++A AL A Sbjct: 113 VVQPENDLIAIGSGGPYAQAAARALLEN--TELSAREIAEKALDIA 156 >5OVU-A nrPDB Length = 197 Score = 52.2 bits (124), Expect = 2e-07, Method: Composition-based stats. Identities = 35/192 (18%), Positives = 70/192 (36%), Gaps = 16/192 (8%) Query: 7 TTTVGLICDDAVILATDKRASLGNLVADKEAK---KLYKIDDYIAMTIAGSVGD---AQA 60 TT V + D V + D + G+ + + K+ + D + +AG+ ++ Sbjct: 1 TTCVVVRKGDEVAIGADALVTFGDTRLSRAYERNQKVIPVGDS-FVGLAGTTAHFPVMRS 59 Query: 61 IVRLLIAEAKLYKMRTGRNIPPLACATLLSNILHSSR----MFPFLTQIIIGGYDLLEGA 116 ++ + E +L+ R L L N + P+ + I+ Sbjct: 60 LLTGMGEECRLHT-RDDVFRTFLKVHEKLKNEYFINTKEDEDDPYESSQIVCLI--ANSG 116 Query: 117 KLFSLDPLGGMNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERDT 176 +F + + F GSG A G + A YDR + + +A +++ +E D Sbjct: 117 GIFGVYSYREVFSFDRFWGIGSGRNYALGAMHAVYDR--TDLDAGAIARIGVEAGIEFDK 174 Query: 177 FSGNGISLAVIT 188 S I + + Sbjct: 175 SSAAPIDVHTVR 186 >1OFH-G nrPDB Length = 174 Score = 52.2 bits (124), Expect = 2e-07, Method: Composition-based stats. Identities = 32/179 (17%), Positives = 67/179 (37%), Gaps = 11/179 (6%) Query: 7 TTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKI-DDYIAMTIAGSVGDAQAIVRLL 65 TT V + + V++ D + SLGN V A+K+ ++ + + AG DA + L Sbjct: 1 TTIVSVRRNGQVVVGGDGQVSLGNTVMKGNARKVRRLYNGKVLAGFAGGTADAFTLFELF 60 Query: 66 IAEAKLYKMRTGRNIPPLACATLLSNILHSSRMFPFLTQIIIGGYDLLEGAKLFSLDPLG 125 + ++++ + L + + +I+ D E + + + Sbjct: 61 ERKLEMHQGHL-----LKSAVELAKDWRTDRALRKLEAMLIVA--DEKESLIITGIGDV- 112 Query: 126 GMNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERDTFSGNGISL 184 EE A GSG A A + + ++ +L+ A + F+ ++ Sbjct: 113 VQPEEDQILAIGSGGNYALSAARALVEN--TELSAHEIVEKSLRIAGDICVFTNTNFTI 169 >1M4Y-A nrPDB Length = 171 Score = 46.1 bits (108), Expect = 1e-05, Method: Composition-based stats. Identities = 32/181 (17%), Positives = 68/181 (37%), Gaps = 16/181 (8%) Query: 7 TTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDD-YIAMTIAGSVGDAQAIVRLL 65 TT + + + ++ D + + G+ V A+K+ K+ + + AGSV DA + Sbjct: 1 TTILVVRRNGQTVMGGDGQVTFGSTVLKGNARKVRKLGEGKVLAGFAGSVADAMTLFDRF 60 Query: 66 IAEAKLYKMRTGRNIPPLACATLLSNILHSSRMFPFLTQIIIGGYDLLEGAKLFSLDPLG 125 A+ + + A L + + +++ + +F + G Sbjct: 61 EAKLREWGGNL-----TKAAVELAKDWRTDRVLRRLEALLLVA-----DKENIFIISGNG 110 Query: 126 GMNE-EKTFTATGSGSPIAYGVLEAGYDR-DMSVEEGIKLALNALKSAMERDTFSGNGIS 183 + + + A GSG P A +A D+S ++ A+ A E ++ I Sbjct: 111 EVIQPDDDAAAIGSGGPYALAAAKALLRNTDLS---AREIVEKAMTIAGEICIYTNQNIV 167 Query: 184 L 184 + Sbjct: 168 I 168 >2Z3B-A nrPDB Length = 180 Score = 43.7 bits (102), Expect = 6e-05, Method: Composition-based stats. Identities = 40/186 (21%), Positives = 67/186 (36%), Gaps = 19/186 (10%) Query: 5 KGTTTVGLICDDAVILATDKRASLGNLVADK-EAKKLYKI-DDYIAMTIAGSVGDAQAIV 62 TT + ++ D + + G V K A+K+ K+ + + AGSV DA + Sbjct: 4 HATTIFAVQHKGRSAMSGDGQVTFGQAVVMKHTARKVRKLFNGKVLAGFAGSVADAFTLF 63 Query: 63 RLLIAEAKLYKMRTGRNIPPLACATLLSNILHSSRMFPFLTQIIIGGYDLLEGAKLFSLD 122 A+ + Y R A L + +I+ D L + Sbjct: 64 EKFEAKLEEYNGNLKR-----AAVELAKEWRSDKVLRKLEAMLIVMNQDT-----LLLVS 113 Query: 123 PLGGMNE-EKTFTATGSGSPIAYG---VLEAGYDRDMSVEEGIKLALNALKSAMERDTFS 178 G + E + A GSG A L+ MS ++A AL++A E ++ Sbjct: 114 GTGEVIEPDDGILAIGSGGNYALAAGRALKKHAGESMS---ASEIARAALETAGEICVYT 170 Query: 179 GNGISL 184 + I L Sbjct: 171 NDQIIL 176 >3TY6-A nrPDB Length = 183 Score = 38.0 bits (87), Expect = 0.003, Method: Composition-based stats. Identities = 31/188 (16%), Positives = 69/188 (36%), Gaps = 23/188 (12%) Query: 5 KGTTTVGLICDDAVILATDKRASLGNLVAD----KEAKKLYKIDDYIAMTIAGSVGDAQA 60 TT + + +A D + ++GN V ++ +KL++ + AGSV DA Sbjct: 8 HATTIFAVHHNGECAMAGDGQVTMGNAVVMKHTARKVRKLFQ--GKVLAGFAGSVADAFT 65 Query: 61 IVRLLIAEAKLYKMRTGRNIPPLACATLLSNILHSSRMFPFLTQIIIGGYDLLEGAKLFS 120 + + + + Y R A + + +I+ ++ + Sbjct: 66 LFEMFEGKLEEYNGNLQR-----AAVEMAKQWRGDKMLRQLEAMLIV-----MDKTTMLL 115 Query: 121 LDPLGGMNE-EKTFTATGSGSPIAYG---VLEAGYDRDMSVEEGIKLALNALKSAMERDT 176 + G + E + A GSG A L+ ++ ++A +L+ A + Sbjct: 116 VSGTGEVIEPDDGILAIGSGGNYALSAGRALKQYASEHLT---AKQIAKASLEIAGDICV 172 Query: 177 FSGNGISL 184 ++ + I + Sbjct: 173 YTNHNIIV 180 >1RFZ-A nrPDB Length = 168 Score = 30.6 bits (68), Expect = 0.60, Method: Composition-based stats. Identities = 12/46 (26%), Positives = 21/46 (45%), Gaps = 1/46 (2%) Query: 146 VLEAGYDRDMSVEEGIKLALNALKSAMERDTFSGNGISLAVITKDG 191 L++ Y D+++EE I+ + E GI L + +DG Sbjct: 36 YLQSKYHPDLTMEECIENVNRVISKR-EVQNAILTGIQLDKLAEDG 80 >3K57-A nrPDB Length = 786 Score = 30.3 bits (67), Expect = 0.63, Method: Composition-based stats. Identities = 12/52 (23%), Positives = 21/52 (40%), Gaps = 4/52 (7%) Query: 51 IAGSVGDAQAIVRLLIAEAKLYKMRTGRNIPPLACATLLSNILHSSRMFPFL 102 +AG + DA+ + + RN+PP A L++ + R P Sbjct: 677 MAGEL-DARLV---YRKRLRRPLSEYQRNVPPHVRAARLADEENQKRGRPLQ 724 >1CEV-A nrPDB Length = 299 Score = 29.5 bits (65), Expect = 1.1, Method: Composition-based stats. Identities = 16/94 (17%), Positives = 34/94 (36%), Gaps = 13/94 (13%) Query: 110 YDLLEGAKLFSLDPLGGMNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALK 169 YD P G ++ + G G P + GY + E + + + +L Sbjct: 121 YDAHGDVNTAETSPSGNIHGMPLAASLGFGHPALTQI--GGYSPKIKPEHVVLIGVRSLD 178 Query: 170 SAMERDTFSGNGISLAVITKDGVKIFEDEEIEKI 203 ++ I + G+KI+ E++++ Sbjct: 179 EGEKKF-----------IREKGIKIYTMHEVDRL 201 >1HH2-P nrPDB Length = 344 Score = 29.5 bits (65), Expect = 1.1, Method: Composition-based stats. Identities = 11/72 (15%), Positives = 39/72 (54%), Gaps = 6/72 (8%) Query: 152 DRDMSVEEGIKLALNALKSAMERDTFSGNGISLAVITKD--GVKIFEDEEIEKILDSMKA 209 ++ +S EE I + AL SA ++ + + + VI ++ +K++ ++ ++++ ++ Sbjct: 15 EKGISKEEVIPILEKALVSAYRKNFGNSKNVEV-VIDRNTGNIKVY---QLLEVVEEVED 70 Query: 210 KPKKKTTKRSRR 221 + + + +++ Sbjct: 71 PATQISLEEAKK 82 >3OPY-B nrPDB Length = 941 Score = 29.1 bits (64), Expect = 1.5, Method: Composition-based stats. Identities = 14/101 (13%), Positives = 36/101 (35%), Gaps = 5/101 (4%) Query: 111 DLLEGAKLFSLDPLGGMNEEKTFT---ATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNA 167 + + +++++DPLG + F A S + E Y + E+ + Sbjct: 124 NEISPFEVYTVDPLGSLIGFSGFKNPFAVNERSLLPKVSEEKAYRAEDDSEKLLNPVRKT 183 Query: 168 LKSAMERDTFSGNGISLAVITKDGVKIFEDEEIEKILDSMK 208 + G + + + G I++ ++ I + + Sbjct: 184 IGVMTSGGDSPGMNPFVRAVVRAG--IYKGCKVFCIHEGYE 222 >1MZD-A nrPDB Length = 240 Score = 29.1 bits (64), Expect = 1.6, Method: Composition-based stats. Identities = 16/83 (19%), Positives = 25/83 (30%), Gaps = 8/83 (9%) Query: 78 RNIPPLACATLLSNILHSSRMFPFLTQIIIGGYDLLEGAKLFSLDPLGGMNEEKTFTATG 137 R + + L N PF+T+ ++ D D G + + F A Sbjct: 145 REVTVTVLSRKLCNSQSYYNGDPFITKDMVCAGDAKGQKDSCKGDAGGPLICKGVFHAIV 204 Query: 138 SGSP--------IAYGVLEAGYD 152 SG Y +L Y Sbjct: 205 SGGHECGVATKPGIYTLLTKKYQ 227 >5BQ2-A nrPDB Length = 429 Score = 28.3 bits (62), Expect = 3.0, Method: Composition-based stats. Identities = 15/52 (28%), Positives = 26/52 (50%), Gaps = 9/52 (17%) Query: 3 VMKGTTTV--GL-ICDDAVILATDKRASLGNLVA------DKEAKKLYKIDD 45 +++G T + G+ A ++ATD RAS ++A D ++Y ID Sbjct: 357 LVEGNTAIVTGVPKLKGAPVMATDLRASASLVIAGLVAEGDTLIDRIYHIDR 408 >2E21-A nrPDB Length = 317 Score = 27.9 bits (61), Expect = 3.5, Method: Composition-based stats. Identities = 7/54 (12%), Positives = 25/54 (46%), Gaps = 2/54 (3%) Query: 23 DKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIVRLLIAEAKLYKMRT 76 + R ++A + +K++ + + + +G V D+ + +L+ + ++ Sbjct: 4 ESRVIR-KVLALQNDEKIFSGERRVLIAFSGGV-DSVVLTDVLLKLKNYFSLKE 55 >2WQK-A nrPDB Length = 251 Score = 27.9 bits (61), Expect = 3.7, Method: Composition-based stats. Identities = 21/92 (22%), Positives = 37/92 (40%), Gaps = 4/92 (4%) Query: 18 VILATDKRAS-LGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIVRLLIAEAKLYKMRT 76 V++A D+ S +G+ + E K+ KID I G+ D + +I E K + Sbjct: 31 VVVAPDRNLSGVGHSLTFTEPLKMRKIDTDFYTVIDGTPADCVHLGYRVILEEKKPDLVL 90 Query: 77 GRNIPPLACATLLSNILHSSRMFPFLTQIIIG 108 L +I +S + + I+G Sbjct: 91 SG---INEGPNLGEDITYSGTVSGAMEGRILG 119 >5TSG-B nrPDB Length = 588 Score = 27.6 bits (60), Expect = 4.9, Method: Composition-based stats. Identities = 14/100 (14%), Positives = 29/100 (29%), Gaps = 1/100 (1%) Query: 80 IPPLACATLLSNILHSSRMFPFLTQIIIGGYDLLEGAKLFSLDPLGGMNEEKTFTATGSG 139 I A + + P +I G EG G + T G Sbjct: 468 ITAQRLARRVCSECKQPEEIPIQA-LIDAGVSPDEGPSYVCYKGTGCVKCNNTGYKGRVG 526 Query: 140 SPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERDTFSG 179 +LE + ++ ++ +++ ++ SG Sbjct: 527 FYQVMPMLEEIRELILNGANTAEIKRESMRLGIKTMRQSG 566 >6IOK-I nrPDB Length = 362 Score = 27.2 bits (59), Expect = 6.0, Method: Composition-based stats. Identities = 13/63 (20%), Positives = 25/63 (39%), Gaps = 6/63 (9%) Query: 90 SNILHSSRMFPFLTQIIIG-----GYDLLEGAKLFSLDPLGGMNEEKTFTA-TGSGSPIA 143 +N + + P + II+ G D+ G +L+ +DP + ++ A S A Sbjct: 37 TNAFRIAEVRPQVNGIILKRLFKEGSDVKAGQQLYQIDPATYEADYQSAQANLASTQEQA 96 Query: 144 YGV 146 Sbjct: 97 QRY 99 >1PQ3-A nrPDB Length = 306 Score = 26.8 bits (58), Expect = 7.2, Method: Composition-based stats. Identities = 19/111 (17%), Positives = 35/111 (31%), Gaps = 6/111 (5%) Query: 67 AEAKLYKMRTGRNIPPLACATLLSNILHSSRMFPFLTQIIIGGYDLLEGAKLFSLDPLGG 126 + + + MR + ++L R P I +D + G Sbjct: 189 YDIQYFSMRDIDRLGIQKVMERTFDLLIGKRQRPIHLSFDIDAFDPTLAPATGTPVVGGL 248 Query: 127 MNEEKTFTA---TGSGSPIAYGVLEAGYDRDMSVEEGI---KLALNALKSA 171 E + A +G A ++E S EE LA++ + S+ Sbjct: 249 TYREGMYIAEEIHNTGLLSALDLVEVNPQLATSEEEAKTTANLAVDVIASS 299 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.311 0.149 0.367 Lambda K H 0.267 0.0459 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 8,090,399 Number of Sequences: 36641 Number of extensions: 307785 Number of successful extensions: 1496 Number of sequences better than 10.0: 101 Number of HSP's better than 10.0 without gapping: 161 Number of HSP's successfully gapped in prelim test: 36 Number of HSP's that attempted gapping in prelim test: 1063 Number of HSP's gapped (non-prelim): 206 length of query: 224 length of database: 10,336,785 effective HSP length: 93 effective length of query: 131 effective length of database: 6,929,172 effective search space: 907721532 effective search space used: 907721532 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.1 bits) S2: 58 (26.8 bits)