BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q53H82 (288 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 4AD9-A nrPDB 598 e-172 2OHJ-A nrPDB 51 6e-07 4CHL-A nrPDB 49 2e-06 1XM8-A nrPDB 49 2e-06 3ADR-A nrPDB 47 1e-05 1X8H-A nrPDB 45 4e-05 6DJA-A nrPDB 41 5e-04 6FRM-A nrPDB 40 0.001 6N36-A nrPDB 40 0.002 2UYX-A nrPDB 39 0.002 3DHA-A nrPDB 39 0.003 2Q0J-A nrPDB 38 0.004 2Y8B-A nrPDB 37 0.007 2YNV-A nrPDB 37 0.009 5K4M-A nrPDB 37 0.012 6ETB-A nrPDB 37 0.012 4D02-A nrPDB 36 0.018 5NBK-A nrPDB 36 0.022 1QH5-A nrPDB 35 0.028 3ZNB-A nrPDB 35 0.033 3SD9-A nrPDB 35 0.046 2QED-A nrPDB 34 0.065 3ZQ4-A nrPDB 33 0.13 2P18-A nrPDB 32 0.30 4BP0-A nrPDB 32 0.37 4F6Z-A nrPDB 31 0.48 4UBQ-A nrPDB 31 0.73 5HQ3-A nrPDB 29 2.4 5TXT-B nrPDB 29 2.5 6IP5-2Q nrPDB 28 3.2 1P15-A nrPDB 28 3.4 5B3R-A nrPDB 28 3.6 2XR1-A nrPDB 28 3.6 5A0V-A nrPDB 28 5.2 2Q9U-A nrPDB 28 5.5 3BDD-A nrPDB 28 5.9 1Z7A-A nrPDB 28 6.1 4XWT-A nrPDB 27 7.2 1YQ9-A nrPDB 27 9.9 >4AD9-A nrPDB Length = 289 Score = 598 bits (1543), Expect = e-172, Method: Compositional matrix adjust. Identities = 288/288 (100%), Positives = 288/288 (100%) Query: 1 MAAVLQRVERLSNRVVRVLGCNPGPMTLQGTNTYLVGTGPRRILIDTGEPAIPEYISCLK 60 MAAVLQRVERLSNRVVRVLGCNPGPMTLQGTNTYLVGTGPRRILIDTGEPAIPEYISCLK Sbjct: 2 MAAVLQRVERLSNRVVRVLGCNPGPMTLQGTNTYLVGTGPRRILIDTGEPAIPEYISCLK 61 Query: 61 QALTEFNTAIQEIVVTHWHRDHSGGIGDICKSINNDTTYCIKKLPRNPQREEIIGNGEQQ 120 QALTEFNTAIQEIVVTHWHRDHSGGIGDICKSINNDTTYCIKKLPRNPQREEIIGNGEQQ Sbjct: 62 QALTEFNTAIQEIVVTHWHRDHSGGIGDICKSINNDTTYCIKKLPRNPQREEIIGNGEQQ 121 Query: 121 YVYLKDGDVIKTEGATLRVLYTPGHTDDHMALLLEEENAIFSGDCILGEGTTVFEDLYDY 180 YVYLKDGDVIKTEGATLRVLYTPGHTDDHMALLLEEENAIFSGDCILGEGTTVFEDLYDY Sbjct: 122 YVYLKDGDVIKTEGATLRVLYTPGHTDDHMALLLEEENAIFSGDCILGEGTTVFEDLYDY 181 Query: 181 MNSLKELLKIKADIIYPGHGPVIHNAEAKIQQYISHRNIREQQILTLFRENFEKSFTVME 240 MNSLKELLKIKADIIYPGHGPVIHNAEAKIQQYISHRNIREQQILTLFRENFEKSFTVME Sbjct: 182 MNSLKELLKIKADIIYPGHGPVIHNAEAKIQQYISHRNIREQQILTLFRENFEKSFTVME 241 Query: 241 LVKIIYKNTPENLHEMAKHNLLLHLKKLEKEGKIFSNTDPDKKWKAHL 288 LVKIIYKNTPENLHEMAKHNLLLHLKKLEKEGKIFSNTDPDKKWKAHL Sbjct: 242 LVKIIYKNTPENLHEMAKHNLLLHLKKLEKEGKIFSNTDPDKKWKAHL 289 >2OHJ-A nrPDB Length = 404 Score = 50.8 bits (120), Expect = 6e-07, Method: Compositional matrix adjust. Identities = 47/150 (31%), Positives = 70/150 (46%), Gaps = 16/150 (10%) Query: 27 TLQGT--NTYLVGTGPRRILIDTGEPA-IPEYISCLKQALTEFNTA-IQEIVVTHWHRDH 82 TLQGT N YLV LID P E ++ ++ AL + + I+ H +DH Sbjct: 29 TLQGTTYNAYLVCGDEGVALIDNSYPGTFDELMARVEDALQQVGMERVDYIIQNHVEKDH 88 Query: 83 SGGIGDICKSINNDTTYC----IKKLPRN-PQREEIIGNGEQQYVYLKDGDVIKTEGATL 137 SG + ++ + YC +K L ++ P E +++ +K GDV+ G TL Sbjct: 89 SGVLVELHRRFPEAPIYCTEVAVKGLLKHYPSLRE------AEFMTVKTGDVLDLGGKTL 142 Query: 138 RVLYTPG-HTDDHMALLLEEENAIFSGDCI 166 L TP H D M LL+E+ +FS D Sbjct: 143 TFLETPLLHWPDSMFTLLDEDGILFSNDAF 172 >4CHL-A nrPDB Length = 238 Score = 49.3 bits (116), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 50/179 (27%), Positives = 79/179 (44%), Gaps = 28/179 (15%) Query: 31 TNTYLVGTGPRR--ILIDTGEPAIPEYISCLKQALTEFNTAIQEIVVTHWHRDHSGGIGD 88 T TYL+G R +LID P Q + E + V TH H DH G G Sbjct: 19 TFTYLLGDRESREAVLIDPVLETAPRD----AQLIKELGLRLLYAVNTHCHADHITGSG- 73 Query: 89 ICKSINNDTTYCIKKLPRNPQREEIIGNGEQQYVYLKDGDVIKTEGATLRVLYTPGHTDD 148 + +S+ I +L +G Q ++++DGD I+ L +PGHT Sbjct: 74 LLRSLLPGCQSVISRL-----------SGAQADLHIEDGDSIRFGRFALETRASPGHTPG 122 Query: 149 HMALLLEEENAIFSGDCIL--GEGTTVFED-----LYDYMNSLKELLKIKAD-IIYPGH 199 + +L + + F+GD +L G G T F+ LY ++ +++ + D +IYP H Sbjct: 123 CVTFVLNDHSMAFTGDALLIRGCGRTDFQQGCAKTLYHSVH--EKIFTLPGDCLIYPAH 179 >1XM8-A nrPDB Length = 254 Score = 48.9 bits (115), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 52/197 (26%), Positives = 85/197 (43%), Gaps = 25/197 (12%) Query: 46 DTGEPAI--PEYISCLKQALTEFNTAIQEIVVTHWHRDHSGGIGDICKSINNDTTYCIKK 103 DTG + P + +L + I+ TH H DH+GG ++ Y K Sbjct: 21 DTGTVGVVDPSEAEPIIDSLKRSGRNLTYILNTHHHYDHTGG------NLELKDRYGAKV 74 Query: 104 LPRNPQREEIIGNGEQQYVYLKDGDVIKTEGATLRVLYTPGHTDDHMALLLEEENAIFSG 163 + ++ I G + LKDGD G + V+ TPGHT H++L AIF+G Sbjct: 75 IGSAMDKDRIPGID----MALKDGDKWMFAGHEVHVMDTPGHTKGHISLYFPGSRAIFTG 130 Query: 164 DCILG-EGTTVFEDLYDYM-NSLKELLKIKADI-IYPGHGPVIHNAEAK---------IQ 211 D + +FE M SL+++ + D IY GH + N++ +Q Sbjct: 131 DTMFSLSCGKLFEGTPKQMLASLQKITSLPDDTSIYCGHEYTLSNSKFALSLEPNNEVLQ 190 Query: 212 QYISH-RNIREQQILTL 227 Y +H +R +++ T+ Sbjct: 191 SYAAHVAELRSKKLPTI 207 >3ADR-A nrPDB Length = 261 Score = 47.0 bits (110), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 57/235 (24%), Positives = 101/235 (42%), Gaps = 54/235 (22%) Query: 24 GPMTLQGTNTYLVGTGPR-RILIDTGEPAIPEYISCLKQALTEFN--TAIQEIVVTHWHR 80 GP+ T V G + ++ID G + ++ +F+ + IV+TH H Sbjct: 12 GPVEFPEIATVYVMCGEKLTVMIDAG----------VSNSIADFSFLDKLDYIVLTHLHI 61 Query: 81 DHSGGIGDICKSINNDTTY------------CIKKLPRNPQREEIIGNGEQQYVY----- 123 DH G + ++ + +KKL N E+++G+ YVY Sbjct: 62 DHIGLLPELLQVYKAKVLVKSGFKKYLTSEDGLKKL--NESAEKVLGD--LYYVYGGLEK 117 Query: 124 -LKDGDVIKTEG--------ATLRVLYTPGHTDDHMALLLEEENAIFSGDC-------IL 167 L VI+ EG +R++YTPGH HM++L+ ++ +F+GD ++ Sbjct: 118 KLDQDKVIEVEGNEEFDLGGYRMRLIYTPGHARHHMSVLV--DDFLFTGDSAGAYFNGVV 175 Query: 168 GEGTTVFEDLYDYMNSLKELLKIKADIIYPGHGPVIHN--AEAKIQQYISHRNIR 220 T D YM SLK +++K ++ HG ++ E ++Q +S I+ Sbjct: 176 IPTTPPVIDYKMYMESLKRQIELKPKVVGFAHGGLVSPKIMEEHLKQMLSKEEIQ 230 >1X8H-A nrPDB Length = 228 Score = 45.1 bits (105), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 42/159 (26%), Positives = 66/159 (41%), Gaps = 28/159 (17%) Query: 70 IQEIVVTHWHRDHSGG------IG----------DICKSINND-TTYCIKKLPRNPQREE 112 + E++ T++H D +GG IG D+ KS + + K LP P Sbjct: 61 VLEVINTNYHTDRAGGNAYWKSIGAKVVSTRQTRDLMKSDWAEIVAFTRKGLPEYPDLPL 120 Query: 113 IIGNGEQQYVYLKDGDVIKTEGATLRVLYTPGHTDDHMALLLEEENAIFSGDCILGE--G 170 ++ N + DGD EG P HT D + + +E ++ G CIL E G Sbjct: 121 VLPN------VVHDGDFTLQEGKVRAFYAGPAHTPDGIFVYFPDEQVLYGG-CILKEKLG 173 Query: 171 TTVFEDLYDYMNSLKEL--LKIKADIIYPGHGPVIHNAE 207 F D+ Y +L+ L +K+ + GH +H E Sbjct: 174 NLSFADVKAYPQTLERLKAMKLPIKTVIGGHDSPLHGPE 212 >6DJA-A nrPDB Length = 222 Score = 41.2 bits (95), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 43/184 (23%), Positives = 87/184 (47%), Gaps = 23/184 (12%) Query: 31 TNTYLVGTGPRRILIDTG--EPAIPEYISCLKQALTEFNTAIQEIVVTHWHRDHSGGIGD 88 +N ++ T +L+D+ + E I +++ +F + ++++TH H D GG+ Sbjct: 36 SNGLVLNTSKGLVLVDSSWDDKLTKELIEMVEK---KFKKRVTDVIITHAHADRIGGMKT 92 Query: 89 IC-KSINNDTTYCIKKLPRNPQREEIIGNGEQQYVYLKDGDVIKTEGATLRVLY-TPGHT 146 + + I +T +L + EE +G+ Q LK G++ + Y GHT Sbjct: 93 LKERGIKAHSTALTAELAKKNGYEEPLGD-LQSVTNLKFGNM------KVETFYPGKGHT 145 Query: 147 DDHMALLLEEENAIFSGDCILGEGTTV----FEDLY--DYMNSLKELLKIKADI--IYPG 198 +D++ + L + I +G C++ ++ D Y ++ S++ +LK +I + PG Sbjct: 146 EDNIVVWLPQYQ-ILAGGCLVKSASSKDLGNVADAYVNEWSTSIENVLKRYGNINLVVPG 204 Query: 199 HGPV 202 HG V Sbjct: 205 HGEV 208 >6FRM-A nrPDB Length = 410 Score = 40.4 bits (93), Expect = 0.001, Method: Compositional matrix adjust. Identities = 45/149 (30%), Positives = 58/149 (38%), Gaps = 13/149 (8%) Query: 27 TLQGT--NTYLVGTGPRRILIDTGEPAIPEYI------SCLKQALTEFNTAIQEIVVTHW 78 TL GT N YLV + LID P + +C K+ EF I IV H Sbjct: 29 TLNGTTYNAYLVFGDDKVALIDNTYPGTSAQMWGRIKDACEKEG-REFK--IDVIVQNHV 85 Query: 79 HRDHSGGIGDICKSINNDTTYCIKKLPRNPQREEIIGNGEQQYVYLKDGDVIKTEGATLR 138 +DHSG + +I K YC + + G + +K + I G TL Sbjct: 86 EKDHSGALPEIHKKFPEAPIYCTEVAVEGLVKHFPSLKG-APFKVVKSLESIDLGGKTLT 144 Query: 139 VLYTP-GHTDDHMALLLEEENAIFSGDCI 166 L P H D M L EE +FS D Sbjct: 145 FLEAPLLHWPDSMFTLYAEEGILFSNDAF 173 >6N36-A nrPDB Length = 271 Score = 39.7 bits (91), Expect = 0.002, Method: Compositional matrix adjust. Identities = 42/190 (22%), Positives = 77/190 (40%), Gaps = 25/190 (13%) Query: 34 YLVGTGPRRILIDTGEPAIPEYISCLKQALTEFNTAIQEIVVTHWHRDHSGGIGDI---- 89 +L+ T ILI+TG I + L I+ ++ TH H DH G + + Sbjct: 40 FLITTPKGHILINTGVAGSDTLIKAHMKTLGFKFKDIRILLTTHAHYDHVGAMAAVKQQT 99 Query: 90 -CKSINNDTTYCIKKLPRNPQREEIIGNGEQQYVYLK------DGDVIKTEGATLRVLYT 142 K + N+ + L + ++G ++ +K DGD I+ G + + Sbjct: 100 HAKMMVNEKDAAL--LADGGNSDYVMGGKGSMFLPVKADRLLHDGDSIQLGGMKIVMRQH 157 Query: 143 PGHTDDHMALLLEEENAIFSGDCILGEGTTVFED-------LY-----DYMNSLKELLKI 190 PGHT + L + ++A+ + ++ ++ D LY DY +LK + + Sbjct: 158 PGHTPGANSFLFDVKDAVRTYKVLIANIPSILNDTKLSGMPLYPEVGKDYAYTLKAMKAL 217 Query: 191 KADIIYPGHG 200 K D+ H Sbjct: 218 KFDLWLAPHA 227 >2UYX-A nrPDB Length = 228 Score = 38.9 bits (89), Expect = 0.002, Method: Compositional matrix adjust. Identities = 47/186 (25%), Positives = 89/186 (47%), Gaps = 27/186 (14%) Query: 31 TNTYLVGTGPRRILIDTG--EPAIPEYISCLKQALTEFNTAIQEIVVTHWHRDHSGGIGD 88 +N ++ T +L+D+ + E I +++ +F + ++++TH H GGI Sbjct: 42 SNGLVLNTSKGLVLVDSSWDDKLTKELIEMVEK---KFQKRVTDVIITHAHASRIGGIKT 98 Query: 89 IC-KSINNDTTYCIKKLPRNPQREEIIGNGEQQYVYLKDGDVIKTEGATLRVLY-TPGHT 146 + + I +T +L + EE +G+ Q LK G++ + Y GHT Sbjct: 99 LKERGIKAHSTALTAELAKKNGYEEPLGD-LQTVTNLKFGNM------KVETFYPGKGHT 151 Query: 147 DDHMALLLEEENAIFSGDCILGEGTTVFEDLYD----YMN----SLKELLKIKADI--IY 196 +D++ + L + N I G C++ +T +DL + Y+N S++ +LK +I + Sbjct: 152 EDNIVVWLPQYN-ILVGGCLV--KSTSAKDLGNVADAYVNEWSTSIENVLKRYRNINAVV 208 Query: 197 PGHGPV 202 PGHG V Sbjct: 209 PGHGEV 214 >3DHA-A nrPDB Length = 254 Score = 38.5 bits (88), Expect = 0.003, Method: Compositional matrix adjust. Identities = 41/144 (28%), Positives = 62/144 (43%), Gaps = 25/144 (17%) Query: 73 IVVTHWHRDHSGGIGDICKS--INNDTTYCIKKLPRNPQREEIIGNGEQQYVYLKDGDVI 130 I+ +H H DH+GG G + I T Y +E I+ + + + +GD Sbjct: 104 IISSHLHFDHAGGNGAFTNTPIIVQRTEYEAALHREEYMKECILPHLNYKII---EGDYE 160 Query: 131 KTEGATLRVLYTPGHTDDHMALLLEEENAIFSGDCILGEGTTV----FEDLYDY------ 180 G L LYTPGH+ H +L +E E SG +L + FED + Sbjct: 161 VVPGVQL--LYTPGHSPGHQSLFIETEQ---SGSVLLTIDASYTKENFEDEVPFAGFDPE 215 Query: 181 -----MNSLKELLKIKADIIYPGH 199 + LKE++K + II+ GH Sbjct: 216 LALSSIKRLKEVVKKEKPIIFFGH 239 >2Q0J-A nrPDB Length = 321 Score = 38.1 bits (87), Expect = 0.004, Method: Compositional matrix adjust. Identities = 35/168 (20%), Positives = 65/168 (38%), Gaps = 30/168 (17%) Query: 68 TAIQEIVVTHWHRDHSGGIGDICKSINNDTTYCIKKLPRNPQREEIIG----------NG 117 + + ++TH H DH G + +C + N ++ + + E + Sbjct: 80 SQVHYWLITHKHYDHCGLLPYLCPRLPNVQVLASERTCQAWKSESAVRVVERLNRQLLRA 139 Query: 118 EQQYVYLKDGDVIKTEGAT------------LRVLYTPGHTDDHMALLLEEENAIFSGDC 165 EQ+ D + L+V+ GH+DDH+ +F GD Sbjct: 140 EQRLPEACAWDALPVRAVADGEWLELGPRHRLQVIEAHGHSDDHVVFYDVRRRRLFCGDA 199 Query: 166 I----LGEGTT---VFEDLYDYMNSLKELLKIKADI-IYPGHGPVIHN 205 + EG VF+D+ Y+ SL+ L ++ + + PGHG ++ Sbjct: 200 LGEFDEAEGVWRPLVFDDMEAYLESLERLQRLPTLLQLIPGHGGLLRG 247 >2Y8B-A nrPDB Length = 265 Score = 37.4 bits (85), Expect = 0.007, Method: Compositional matrix adjust. Identities = 43/187 (22%), Positives = 79/187 (42%), Gaps = 23/187 (12%) Query: 27 TLQGTNTYLVGTGPRRILIDTGEPAIPEYISCLKQALTEFNTAIQEIVVTHWHRDHSGGI 86 T+ +N +V +LIDT A ++ L + + + + TH+H D GG+ Sbjct: 64 TVYSSNGLIVRDADELLLIDTAWGA-KNTVALLAEIEKQIGLPVTRSISTHFHDDRVGGV 122 Query: 87 GDICKSINNDTTYCIKKLPRNPQREEIIGN---GEQQYVYLKDGDVIKTEGATLRVLYTP 143 D+ ++ T P Q E GN GDV++ + V Y P Sbjct: 123 -DVLRAAGVATYTS----PLTRQLAEAAGNEVPAHSLKALSSSGDVVRF--GPVEVFY-P 174 Query: 144 G--HTDDHMALLLEEENAIFSGDCILGE------GTTVFEDLYDYMNSLKELLK--IKAD 193 G H+ D++ + + +F G C + E G +L ++ ++K + + +A+ Sbjct: 175 GAAHSGDNLVVYVPAVRVLFGG-CAVHEASRESAGNVADANLAEWPATIKRIQQRYPEAE 233 Query: 194 IIYPGHG 200 ++ PGHG Sbjct: 234 VVIPGHG 240 >2YNV-A nrPDB Length = 233 Score = 37.4 bits (85), Expect = 0.009, Method: Compositional matrix adjust. Identities = 54/186 (29%), Positives = 80/186 (43%), Gaps = 23/186 (12%) Query: 28 LQGTNTYLVGTGPRRILIDTGEPAIPEYISCLKQALTEFNTAIQEIVVTHWHRDHSGGIG 87 L +N +V + +IDT P E L T+ + + TH H D + GI Sbjct: 30 LVDSNGLVVLDNNQAYIIDT--PWSEEDTKLLLSWATDRGYQVMASISTHSHEDRTAGIK 87 Query: 88 DI-CKSINNDTTYCIKKLPRNPQREEIIGNGEQQYVYLKDGDVIKTEGATLRVLYTPG-- 144 + KSI T+ KKL RE G + Y KD + T G L LY PG Sbjct: 88 LLNSKSIPTYTSELTKKLL---ARE---GKPVPTH-YFKDDEF--TLGNGLIELYYPGAG 138 Query: 145 HTDDHMALLLEEENAIFSGDCIL------GEGTTVFEDLYDYMNSLKELLKIKADI--IY 196 HT+D++ L + +F G C++ G G + + +S+K ++ K I + Sbjct: 139 HTEDNIVAWLPKSKILFGG-CLVRSHEWEGLGYVGDASISSWADSIKNIVSKKYPIQMVV 197 Query: 197 PGHGPV 202 PGHG V Sbjct: 198 PGHGKV 203 >5K4M-A nrPDB Length = 245 Score = 36.6 bits (83), Expect = 0.012, Method: Compositional matrix adjust. Identities = 45/178 (25%), Positives = 75/178 (42%), Gaps = 30/178 (16%) Query: 9 ERLSNRVVRVLGCN----------PGPMTLQGTNTYLVGTGPRRILIDTG--EPAIPEYI 56 +R + V R L N PG +N +V G R +++DT + + + Sbjct: 19 QRFGDPVFRQLAPNVWQHTSYLDMPG-FGAVASNGLIVRDGGRVLMVDTAGTDAQTAQIL 77 Query: 57 SCLKQALTEFNTAIQEIVVTHWHRDHSGGIGDICKSINNDTTYCIKKLPRNPQREEIIGN 116 +KQ E N + VVTH H+D GG+ + + TY + RE ++ Sbjct: 78 KWIKQ---EINLPVALAVVTHAHQDKMGGMDALHAA--GIATYANALSNQLAPREGVVA- 131 Query: 117 GEQQYVYLKDGDVIKTEGAT------LRVLYT-PGHTDDHMALLLEEENAIFSGDCIL 167 + + G V E AT L+V Y PGHT D++ + ++ + F G C++ Sbjct: 132 AQHSLTFAATGWV---EPATAPNFGPLKVFYPGPGHTSDNITVGIDGTDIAFGG-CLI 185 >6ETB-A nrPDB Length = 412 Score = 36.6 bits (83), Expect = 0.012, Method: Compositional matrix adjust. Identities = 48/183 (26%), Positives = 80/183 (43%), Gaps = 22/183 (12%) Query: 27 TLQGT--NTYLVGTGPRRILIDTGEPAIP-EYISCLKQALTEFNTA-IQEIVVTHWHRDH 82 TL+G+ N+YL+ + +LIDT + E++ L+ E + A I IV+ H DH Sbjct: 29 TLRGSSYNSYLIRE-EKNVLIDTVDHKFSREFVQNLRN---EIDLADIDYIVINHAEEDH 84 Query: 83 SGGIGDICKSINNDTTYCIKKLPRNPQREEIIG---NGEQQYVYLKDGDVIKT-EGATLR 138 +G + ++ I + YC + I G + E + +K GD + G L Sbjct: 85 AGALTELMAQIPDTPIYCTANAI-----DSINGHHHHPEWNFNVVKTGDTLDIGNGKQLI 139 Query: 139 VLYTPG-HTDDHMALLLEEENAIFSGDCILGE---GTTVFEDLYDYMNSLKELLKIKADI 194 + TP H D M L + +FS D G+ +F D D ++ + A+I Sbjct: 140 FVETPMLHWPDSMMTYLTGDAVLFSNDA-FGQHYCDEHLFNDEVDQTELFEQCQRYYANI 198 Query: 195 IYP 197 + P Sbjct: 199 LTP 201 >4D02-A nrPDB Length = 479 Score = 36.2 bits (82), Expect = 0.018, Method: Compositional matrix adjust. Identities = 48/183 (26%), Positives = 80/183 (43%), Gaps = 22/183 (12%) Query: 27 TLQGT--NTYLVGTGPRRILIDTGEPAIP-EYISCLKQALTEFNTA-IQEIVVTHWHRDH 82 TL+G+ N+YL+ + +LIDT + E++ L+ E + A I IV+ H DH Sbjct: 29 TLRGSSYNSYLIRE-EKNVLIDTVDHKFSREFVQNLRN---EIDLADIDYIVINHAEEDH 84 Query: 83 SGGIGDICKSINNDTTYCIKKLPRNPQREEIIG---NGEQQYVYLKDGDVIKT-EGATLR 138 +G + ++ I + YC + I G + E + +K GD + G L Sbjct: 85 AGALTELMAQIPDTPIYCTAN-----AIDSINGHHHHPEWNFNVVKTGDTLDIGNGKQLI 139 Query: 139 VLYTPG-HTDDHMALLLEEENAIFSGDCILGE---GTTVFEDLYDYMNSLKELLKIKADI 194 + TP H D M L + +FS D G+ +F D D ++ + A+I Sbjct: 140 FVETPMLHWPDSMMTYLTGDAVLFSNDA-FGQHYCDEHLFNDEVDQTELFEQCQRYYANI 198 Query: 195 IYP 197 + P Sbjct: 199 LTP 201 >5NBK-A nrPDB Length = 251 Score = 35.8 bits (81), Expect = 0.022, Method: Compositional matrix adjust. Identities = 42/175 (24%), Positives = 73/175 (41%), Gaps = 24/175 (13%) Query: 9 ERLSNRVVRVLGCN----------PGPMTLQGTNTYLVGTGPRRILIDTG--EPAIPEYI 56 +R + V R L N PG +N +V G R +++DT + + + Sbjct: 17 QRFGDLVFRQLAPNVWQHTSYLDMPG-FGAVASNGLIVRDGGRVLVVDTAWTDDQTAQIL 75 Query: 57 SCLKQALTEFNTAIQEIVVTHWHRDHSGGIGDICKSINNDTTYCIKKLPRNPQREEIIGN 116 + +KQ E N + VVTH H+D GG+ + + TY L +E + Sbjct: 76 NWIKQ---EINLPVALAVVTHAHQDKMGGMDALHAA--GIATYA-NALSNQLAPQEGMVA 129 Query: 117 GEQQYVYLKDGDVIKTEG---ATLRVLYT-PGHTDDHMALLLEEENAIFSGDCIL 167 + + +G V L+V Y PGHT D++ + ++ + F G C++ Sbjct: 130 AQHSLTFAANGWVEPATAPNFGPLKVFYPGPGHTSDNITVGIDGTDIAFGG-CLI 183 >1QH5-A nrPDB Length = 260 Score = 35.4 bits (80), Expect = 0.028, Method: Compositional matrix adjust. Identities = 47/198 (23%), Positives = 83/198 (41%), Gaps = 25/198 (12%) Query: 46 DTGEPAIPEYISCLK--QALTEFNTAIQEIVVTHWHRDHSGGIGDICKSINNDTTYCIKK 103 +T E AI + + K A + + ++ TH H DH+GG + K + Y Sbjct: 21 ETKEAAIVDPVQPQKVVDAARKHGVKLTTVLTTHHHWDHAGGNEKLVKLESGLKVY---- 76 Query: 104 LPRNPQREEIIGNGEQQYVYLKDGDVIKTEGATLRVLYTPGHTDDHMALLL-----EEEN 158 ++ IG + +L ++ ++ L TP HT H+ + E Sbjct: 77 -----GGDDRIGALTHKITHL---STLQVGSLNVKCLATPCHTSGHICYFVSKPGGSEPP 128 Query: 159 AIFSGDCILGEGTTVF-EDLYDYM-NSLKELL-KIKADI-IYPGHGPVIHNAEAKIQQYI 214 A+F+GD + G F E D M +L E+L ++ D +Y GH I+N K +++ Sbjct: 129 AVFTGDTLFVAGCGKFYEGTADEMCKALLEVLGRLPPDTRVYCGHEYTINN--LKFARHV 186 Query: 215 SHRNIREQQILTLFRENF 232 N ++ L +E + Sbjct: 187 EPGNAAIREKLAWAKEKY 204 >3ZNB-A nrPDB Length = 232 Score = 35.0 bits (79), Expect = 0.033, Method: Compositional matrix adjust. Identities = 44/169 (26%), Positives = 67/169 (39%), Gaps = 31/169 (18%) Query: 65 EFNTAIQEIVVTHWHRDHSGGIGDICK----SINNDTTYCIKKLPRNPQREEIIGNGEQQ 120 + + + HWH D GG+G + K S N T + K P E Sbjct: 70 SLHAKVTTFIPNHWHGDCIGGLGYLQKKGVQSYANQMTIDLAKEKGLPVPEH-------- 121 Query: 121 YVYLKDGDVIKTEGATLRVLY-TPGHTDDHMALLLEEENAIFSGDCIL--GEGTTV--FE 175 D + +G L+ Y GH D++ + L EN +F G C+L + T++ Sbjct: 122 --GFTDSLTVSLDGMPLQCYYLGGGHATDNIVVWLPTENILFGG-CMLKDNQATSIGNIS 178 Query: 176 DLYDYMNSLKELLKIKADI-----IYPGHGP-----VIHNAEAKIQQYI 214 D D K L K+KA + PGHG +I + + + QYI Sbjct: 179 DA-DVTAWPKTLDKVKAKFPSARYVVPGHGDYGGTELIEHTKQIVNQYI 226 >3SD9-A nrPDB Length = 233 Score = 34.7 bits (78), Expect = 0.046, Method: Compositional matrix adjust. Identities = 42/163 (25%), Positives = 71/163 (43%), Gaps = 34/163 (20%) Query: 70 IQEIVVTHWHRDHSGG------IGDICKSINNDTTYCIKKLPRNPQREEIIG---NGEQQ 120 I E++ T++H D +GG +G K + TY ++K Q I+ G + Sbjct: 64 INEVINTNYHTDRAGGNAYWKTLG--AKIVATQMTYDLQK----SQWGSIVNFTRQGNNK 117 Query: 121 YVYLKD--------GDVIKTEGATLRVLYT-PGHTDDHMALLLEEENAIFSGDCILGE-- 169 Y L+ GD + ++R +Y HT D + + E ++ G+CIL E Sbjct: 118 YPNLEKSLPDTVFPGD-FNLQNGSIRAMYLGEAHTKDGIFVYFPAERVLY-GNCILKENL 175 Query: 170 GTTVFEDLYDYMNSLKELL------KIKADIIYPGHGPVIHNA 206 G F + +Y +L++L ++K D I GH IH+ Sbjct: 176 GNMSFANRTEYPKTLEKLKGLIEQGELKVDSIIAGHDTPIHDV 218 >2QED-A nrPDB Length = 258 Score = 34.3 bits (77), Expect = 0.065, Method: Compositional matrix adjust. Identities = 39/136 (28%), Positives = 58/136 (42%), Gaps = 22/136 (16%) Query: 41 RRILIDTGEPAIPEYISCLKQALTEFNTAIQEIVVTHWHRDHSGGIGDICKSINNDTTYC 100 R +++D GE A + +A+ E + I +TH H DH GG+ ++ + T Y Sbjct: 30 RCVIVDPGEAAP------VLKAIAEHKWMPEAIFLTHHHHDHVGGVKELLQHFPQMTVY- 82 Query: 101 IKKLPRNPQREEIIGNGEQQYVYLKDGDVIKTEGATLRVLYTPGHTDDHMALL----LEE 156 P + G + DGD I+ G + TPGHT H+ L Sbjct: 83 ------GPAETQDKGATH----LVGDGDTIRVLGEKFTLFATPGHTLGHVCYFSRPYLFC 132 Query: 157 ENAIFSGDC-ILGEGT 171 + +FSG C L EGT Sbjct: 133 GDTLFSGGCGRLFEGT 148 >3ZQ4-A nrPDB Length = 555 Score = 33.1 bits (74), Expect = 0.13, Method: Compositional matrix adjust. Identities = 23/76 (30%), Positives = 33/76 (43%), Gaps = 16/76 (21%) Query: 30 GTNTYLVGTGPRRILIDTG-----------EPAIPEYISCLKQALTEFNTAIQEIVVTHW 78 G NTY V +LID G + IP+Y +K I+ + +TH Sbjct: 21 GKNTYAVQFQDEIVLIDAGIKFPEDELLGIDYVIPDYTYLVKN-----EDKIKGLFITHG 75 Query: 79 HRDHSGGIGDICKSIN 94 H DH GGI + + +N Sbjct: 76 HEDHIGGIPYLLRQVN 91 >2P18-A nrPDB Length = 311 Score = 32.0 bits (71), Expect = 0.30, Method: Compositional matrix adjust. Identities = 34/159 (21%), Positives = 61/159 (38%), Gaps = 26/159 (16%) Query: 60 KQALTEFNTAIQEIVVTHWHRDHSGGIGDICKSIN--NDTTYCIKKLPRNPQREEIIGNG 117 +Q + I+ TH H DHSGG + + N T + N + Sbjct: 75 QQGNADVTYTFSTILSTHKHWDHSGGNAKLKAELEAMNSTVPVVVVGGANDSIPAVTKP- 133 Query: 118 EQQYVYLKDGDVIKTEGATLRVLYTPGHTDDHMALLLEEEN------AIFSGDCILGEGT 171 +++GD ++ ++ V+ P HT H+ ++ A+F+GD + G Sbjct: 134 ------VREGDRVQVGDLSVEVIDAPCHTRGHVLYKVQHPQHPNDGVALFTGDTMFIAGI 187 Query: 172 TVF--EDLYDYMNSLKELLKI---------KADIIYPGH 199 F D D +++++ I K I+PGH Sbjct: 188 GAFFEGDEKDMCRAMEKVYHIHKGNDYALDKVTFIFPGH 226 >4BP0-A nrPDB Length = 250 Score = 31.6 bits (70), Expect = 0.37, Method: Compositional matrix adjust. Identities = 21/81 (25%), Positives = 38/81 (46%), Gaps = 5/81 (6%) Query: 124 LKDGDVIKTEGATLRVLYT-PGHTDDHMALLLEEENAIFSGDCILGE---GTTVFEDLYD 179 LK G V + V + P H+ D++ + ++ +F G C++ G ++ Sbjct: 147 LKQGKVFSFSNELVEVSFPGPAHSPDNVVVYFPKKKLLFGG-CMIKPKELGYLGDANVKA 205 Query: 180 YMNSLKELLKIKADIIYPGHG 200 + +S + L K A I+ PGHG Sbjct: 206 WPDSARRLKKFDAKIVIPGHG 226 >4F6Z-A nrPDB Length = 236 Score = 31.2 bits (69), Expect = 0.48, Method: Compositional matrix adjust. Identities = 43/166 (25%), Positives = 70/166 (42%), Gaps = 18/166 (10%) Query: 44 LIDTGEPAIPEYISCLKQALTEFNTAIQEIVVTHWHRDHSGGIGDI-CKSINNDTTYCIK 102 LIDT P + L E I+ + +H+H D +GGI + +SI + Sbjct: 46 LIDT--PFTAKDTEKLVTWFVERGYKIKGSISSHFHSDSTGGIEWLNSRSIPTYASELTN 103 Query: 103 KLPRNPQREEIIGNGEQQYVYLKDGDVIKTEGATLRVLYT-PGHTDDHMALLLEEENAIF 161 +L + + + + +L +K + + V Y PGHT D++ + L E +F Sbjct: 104 ELLKKDGKVQATNSFSGVNYWL-----VKNK---IEVFYPGPGHTPDNVVVWLPERKILF 155 Query: 162 SGDCI--LGEGTTVFEDLYDYMNSLKELLKI---KADIIYPGHGPV 202 G I G G ++ + S K LLK KA ++ P H V Sbjct: 156 GGGFIKPYGLGNLGDANIEAWPKSAK-LLKSKYGKAKLVVPSHSEV 200 >4UBQ-A nrPDB Length = 229 Score = 30.8 bits (68), Expect = 0.73, Method: Compositional matrix adjust. Identities = 42/170 (24%), Positives = 67/170 (39%), Gaps = 26/170 (15%) Query: 44 LIDTGEPAIPEYISCLKQALTEFNTAIQEIVVTHWHRDHSGGI-----GDICKSINNDTT 98 LIDT P L E I+ + +H+H D +GGI I + T Sbjct: 47 LIDT--PFTATDTEKLVNWFVERGYKIKGTISSHFHSDSTGGIEWLNSQSIPTYASELTN 104 Query: 99 YCIKKLPRNPQREEIIGNGEQQYVYLKDGDVIKTEGATLRVLYT-PGHTDDHMALLLEEE 157 +KK + + G Y +K+ + V Y PGHT D++ + L E+ Sbjct: 105 ELLKKDGKVQAKNSFSG---VSYWLVKN---------KIEVFYPGPGHTQDNVVVWLPEK 152 Query: 158 NAIFSGDCIL---GEGTTVFEDLYDYMNSLKELLK--IKADIIYPGHGPV 202 +F G C + G G +L + S K L+ +KA ++ H + Sbjct: 153 KILFGG-CFVKPDGLGNLGDANLEAWPKSAKILMSKYVKAKLVVSSHSEI 201 >5HQ3-A nrPDB Length = 548 Score = 28.9 bits (63), Expect = 2.4, Method: Compositional matrix adjust. Identities = 39/152 (25%), Positives = 62/152 (40%), Gaps = 35/152 (23%) Query: 6 QRVERLSNRVVRVLGCNPGPMTLQGTNTYLVGTGPRRILIDTGEPAIPEYISCLKQALTE 65 + R + ++ +++GC PG GTG DT E ++CL+ Sbjct: 243 EEARRRALQLAKLVGCPPG------------GTGGN----DT------ELVACLR----- 275 Query: 66 FNTAIQEIVVTHWHRDHSGGIGDICKSINNDTTYCIKKLPRNPQREEIIGNGEQQYVYLK 125 N QE+V WH + D + LP P E +I NG+ + + + Sbjct: 276 -NRPPQELVNHEWHVLPQESVFRFSFVPVVDGDF----LPDTP--EALINNGDFKGLDVL 328 Query: 126 DGDVIKTEGATLRVLYTPGHTDDHMALLLEEE 157 G V K EG+ V PG + D+ +L+ EE Sbjct: 329 VG-VNKDEGSYFLVYGAPGFSKDNESLISREE 359 >5TXT-B nrPDB Length = 491 Score = 28.9 bits (63), Expect = 2.5, Method: Compositional matrix adjust. Identities = 16/54 (29%), Positives = 27/54 (50%) Query: 109 QREEIIGNGEQQYVYLKDGDVIKTEGATLRVLYTPGHTDDHMALLLEEENAIFS 162 Q +I+ N Q YV + + LR+ TPGHT+D +L+ + +F+ Sbjct: 375 QASDILINKHQIYVQAINFPTVARGTERLRITPTPGHTNDLSDILINAVDDVFN 428 >6IP5-2Q nrPDB Length = 157 Score = 28.5 bits (62), Expect = 3.2, Method: Compositional matrix adjust. Identities = 28/106 (26%), Positives = 42/106 (39%), Gaps = 17/106 (16%) Query: 186 ELLKIKADIIYPGHGPVIHNAEAKIQQ---------YISHRNIREQQILTLFRENFEKSF 236 EL IYPGHG + K+ Q ++S RN R+ L+R +K Sbjct: 4 ELCSFSGYKIYPGHGRRYARTDGKVFQFLNAKCESAFLSKRNPRQINWTVLYRRKHKKGQ 63 Query: 237 T-------VMELVKIIYKNTPENLHE-MAKHNLLLHLKKLEKEGKI 274 + VK T +L + MAK N ++K ++E I Sbjct: 64 SEEIQKKRTRRAVKFQRAITGASLADIMAKRNQKPEVRKAQREQAI 109 >1P15-A nrPDB Length = 253 Score = 28.5 bits (62), Expect = 3.4, Method: Compositional matrix adjust. Identities = 22/83 (26%), Positives = 33/83 (39%), Gaps = 3/83 (3%) Query: 32 NTYLVGTGPRRILIDTGEPAIPEYISCLKQALTEFNTAIQEIVVTHWHRDHSGGIGDICK 91 ++Y+ GP I+ I E+ SC LTE QE +W D GDI Sbjct: 52 DSYIASQGPLLHTIEDFWRMIWEWKSCSIVMLTELEERGQEKCAQYWPSDGLVSYGDITV 111 Query: 92 SINND---TTYCIKKLPRNPQRE 111 + + +Y ++ L RE Sbjct: 112 ELKKEEECESYTVRDLLVTNTRE 134 >5B3R-A nrPDB Length = 228 Score = 28.5 bits (62), Expect = 3.6, Method: Compositional matrix adjust. Identities = 33/129 (25%), Positives = 56/129 (43%), Gaps = 12/129 (9%) Query: 44 LIDTGEPAIPEYISCLKQALTEFNTAIQEIVVTHWHRDHSGGIGDI-CKSINNDTTYCIK 102 LIDT P + L E I+ + TH+H D + GI + +SI+ + Sbjct: 46 LIDT--PITAKDTEKLVNWFIEHGYRIKGSISTHFHGDSTAGIEWLNSQSISTYASELTN 103 Query: 103 KLPRNPQREEIIGNGEQQYVYLKDGDVIKTEGATLRVLYT-PGHTDDHMALLLEEENAIF 161 +L + + + N Y +IK + + V Y PGHT D++ + L E+ +F Sbjct: 104 ELLKKDNKVQAT-NSFSGVSY----SLIKNK---IEVFYPGPGHTQDNVVVWLPEKKILF 155 Query: 162 SGDCILGEG 170 G + +G Sbjct: 156 GGCFVKPDG 164 >2XR1-A nrPDB Length = 640 Score = 28.5 bits (62), Expect = 3.6, Method: Compositional matrix adjust. Identities = 28/98 (28%), Positives = 38/98 (38%), Gaps = 25/98 (25%) Query: 14 RVVRVLGCNPGPMTLQGTNTYLVGTGPRRILIDTGEPA-----------IPEYISCLKQA 62 RV + GC G + +L+ T RILID G +PE + L Q Sbjct: 185 RVTALGGCKE-----VGRSCFLLSTPESRILIDCGVNVGSDENMTPYLYVPE-VFPLNQ- 237 Query: 63 LTEFNTAIQEIVVTHWHRDHSGGIGDICKSINNDTTYC 100 I ++VTH H DH G + + K YC Sbjct: 238 -------IDAVIVTHAHLDHQGLVPLLFKYGYEGPVYC 268 >5A0V-A nrPDB Length = 561 Score = 28.1 bits (61), Expect = 5.2, Method: Compositional matrix adjust. Identities = 19/63 (30%), Positives = 29/63 (46%), Gaps = 6/63 (9%) Query: 30 GTNTYLVGTGPRRILIDTGEPAIPEYISCLKQALTEFNTA------IQEIVVTHWHRDHS 83 G N + G R +++D G E + L +F + I+ IV+TH H DH Sbjct: 31 GRNMTVFEYGGRLLIVDCGVLFPEEEQPGIDLILPDFTSIRDRLDDIEGIVLTHGHEDHI 90 Query: 84 GGI 86 GG+ Sbjct: 91 GGV 93 >2Q9U-A nrPDB Length = 414 Score = 27.7 bits (60), Expect = 5.5, Method: Compositional matrix adjust. Identities = 23/96 (23%), Positives = 40/96 (41%), Gaps = 3/96 (3%) Query: 70 IQEIVVTHWHRDHSGGIGDICKSINNDTTYCIKKLPRNPQREEIIGNGEQQYVYLKDGDV 129 I+ +V+ H DH+ + D N T C KK + + + G + ++ + D Sbjct: 78 IKYVVMNHAEGDHASSLKDHYHKFTNATFVCTKKCQEHLKI--LYGMEKATWLIVDDKYT 135 Query: 130 IKTEGATLRVLYTP-GHTDDHMALLLEEENAIFSGD 164 +K TL+ + P H D E+ +FS D Sbjct: 136 LKIGKRTLKFIPVPLLHWPDSTFTYCPEDKILFSND 171 >3BDD-A nrPDB Length = 142 Score = 27.7 bits (60), Expect = 5.9, Method: Compositional matrix adjust. Identities = 20/73 (27%), Positives = 34/73 (46%), Gaps = 10/73 (13%) Query: 219 IREQQILTLFRENFEKSFTVMELVKIIYKNTPENLHEMAKHNLL--------LHLKKLEK 270 + ++ I LF + S T +++ + K+ P LH++A L HLK LE+ Sbjct: 14 VADETISNLFEKQLGISLTRYSILQTLLKDAP--LHQLALQERLQIDRAAVTRHLKLLEE 71 Query: 271 EGKIFSNTDPDKK 283 G I +PD + Sbjct: 72 SGYIIRKRNPDNQ 84 >1Z7A-A nrPDB Length = 308 Score = 27.7 bits (60), Expect = 6.1, Method: Compositional matrix adjust. Identities = 14/24 (58%), Positives = 16/24 (66%), Gaps = 1/24 (4%) Query: 114 IGNGEQQYVYLKDG-DVIKTEGAT 136 NGEQ + YLKD DV+ EGAT Sbjct: 226 FNNGEQFFQYLKDAFDVLYEEGAT 249 >4XWT-A nrPDB Length = 559 Score = 27.3 bits (59), Expect = 7.2, Method: Compositional matrix adjust. Identities = 15/46 (32%), Positives = 20/46 (43%), Gaps = 11/46 (23%) Query: 63 LTEFNTAIQEIVVTHWHRDHSGGIGDICKSINNDTTYCIKKLPRNP 108 L E I+ ++TH H DH GG+ Y +LPR P Sbjct: 70 LLEHQDKIKGWILTHGHEDHIGGL-----------PYIFARLPRVP 104 >1YQ9-A nrPDB Length = 264 Score = 26.9 bits (58), Expect = 9.9, Method: Compositional matrix adjust. Identities = 11/37 (29%), Positives = 19/37 (51%) Query: 3 AVLQRVERLSNRVVRVLGCNPGPMTLQGTNTYLVGTG 39 V + + +L + + + GC P PM GT +L+ G Sbjct: 130 GVNEALGKLGVKAINIAGCPPNPMNFVGTVVHLLTKG 166 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 4AD9-A nrPDB 458 e-129 1XM8-A nrPDB 168 2e-42 6N36-A nrPDB 156 1e-38 3ADR-A nrPDB 146 9e-36 2OHJ-A nrPDB 146 1e-35 4CHL-A nrPDB 141 3e-34 6FRM-A nrPDB 132 2e-31 6DJA-A nrPDB 131 5e-31 1X8H-A nrPDB 129 9e-31 Sequences not found previously or not previously below threshold: 2UYX-A nrPDB 121 5e-28 6ETB-A nrPDB 88 4e-18 4D02-A nrPDB 88 4e-18 1YCF-A nrPDB 86 1e-17 2QED-A nrPDB 81 5e-16 3SD9-A nrPDB 80 9e-16 1E5D-A nrPDB 79 1e-15 1QH5-A nrPDB 76 2e-14 2Y8B-A nrPDB 72 2e-13 2YNV-A nrPDB 72 3e-13 5HH5-A nrPDB 71 5e-13 2P18-A nrPDB 69 3e-12 2Q0J-A nrPDB 68 5e-12 4F6Z-A nrPDB 67 8e-12 3ZNB-A nrPDB 67 1e-11 4BP0-A nrPDB 66 2e-11 1M2X-A nrPDB 65 3e-11 4UBQ-A nrPDB 64 5e-11 4DIK-A nrPDB 64 5e-11 2Q9U-A nrPDB 64 1e-10 3L6N-A nrPDB 63 1e-10 5B3R-A nrPDB 60 9e-10 5K4M-A nrPDB 59 2e-09 3DHA-A nrPDB 58 5e-09 3IEL-A nrPDB 53 1e-07 5NBK-A nrPDB 51 4e-07 2XR1-A nrPDB 51 6e-07 2YCB-A nrPDB 51 8e-07 3ZQ4-A nrPDB 49 3e-06 4XWT-A nrPDB 46 2e-05 5A0V-A nrPDB 45 5e-05 3AF5-A nrPDB 44 6e-05 3T3N-A nrPDB 40 0.001 3AJ3-A nrPDB 39 0.002 5HAA-A nrPDB 37 0.007 4PDX-A nrPDB 37 0.008 4AXH-A nrPDB 36 0.017 4NUR-A nrPDB 35 0.045 4B09-A nrPDB 34 0.11 3ZWF-A nrPDB 33 0.13 2CG3-A nrPDB 33 0.16 4GBM-A nrPDB 32 0.38 3BDD-A nrPDB 32 0.43 2N7L-C nrPDB 31 0.54 4V7O-A5 nrPDB 30 1.6 4GCW-A nrPDB 29 1.9 2WJ4-A nrPDB 29 1.9 5MTZ-A nrPDB 29 2.0 3RHD-A nrPDB 29 2.4 2I3C-A nrPDB 29 2.8 2R2D-A nrPDB 29 3.5 4XHZ-A nrPDB 28 3.8 1YQ9-A nrPDB 27 7.1 5TEK-A nrPDB 27 8.9 >4AD9-A nrPDB Length = 289 Score = 458 bits (1179), Expect = e-129, Method: Composition-based stats. Identities = 288/288 (100%), Positives = 288/288 (100%) Query: 1 MAAVLQRVERLSNRVVRVLGCNPGPMTLQGTNTYLVGTGPRRILIDTGEPAIPEYISCLK 60 MAAVLQRVERLSNRVVRVLGCNPGPMTLQGTNTYLVGTGPRRILIDTGEPAIPEYISCLK Sbjct: 2 MAAVLQRVERLSNRVVRVLGCNPGPMTLQGTNTYLVGTGPRRILIDTGEPAIPEYISCLK 61 Query: 61 QALTEFNTAIQEIVVTHWHRDHSGGIGDICKSINNDTTYCIKKLPRNPQREEIIGNGEQQ 120 QALTEFNTAIQEIVVTHWHRDHSGGIGDICKSINNDTTYCIKKLPRNPQREEIIGNGEQQ Sbjct: 62 QALTEFNTAIQEIVVTHWHRDHSGGIGDICKSINNDTTYCIKKLPRNPQREEIIGNGEQQ 121 Query: 121 YVYLKDGDVIKTEGATLRVLYTPGHTDDHMALLLEEENAIFSGDCILGEGTTVFEDLYDY 180 YVYLKDGDVIKTEGATLRVLYTPGHTDDHMALLLEEENAIFSGDCILGEGTTVFEDLYDY Sbjct: 122 YVYLKDGDVIKTEGATLRVLYTPGHTDDHMALLLEEENAIFSGDCILGEGTTVFEDLYDY 181 Query: 181 MNSLKELLKIKADIIYPGHGPVIHNAEAKIQQYISHRNIREQQILTLFRENFEKSFTVME 240 MNSLKELLKIKADIIYPGHGPVIHNAEAKIQQYISHRNIREQQILTLFRENFEKSFTVME Sbjct: 182 MNSLKELLKIKADIIYPGHGPVIHNAEAKIQQYISHRNIREQQILTLFRENFEKSFTVME 241 Query: 241 LVKIIYKNTPENLHEMAKHNLLLHLKKLEKEGKIFSNTDPDKKWKAHL 288 LVKIIYKNTPENLHEMAKHNLLLHLKKLEKEGKIFSNTDPDKKWKAHL Sbjct: 242 LVKIIYKNTPENLHEMAKHNLLLHLKKLEKEGKIFSNTDPDKKWKAHL 289 >1XM8-A nrPDB Length = 254 Score = 168 bits (426), Expect = 2e-42, Method: Composition-based stats. Identities = 52/197 (26%), Positives = 85/197 (43%), Gaps = 25/197 (12%) Query: 46 DTGEPAI--PEYISCLKQALTEFNTAIQEIVVTHWHRDHSGGIGDICKSINNDTTYCIKK 103 DTG + P + +L + I+ TH H DH+GG ++ Y K Sbjct: 21 DTGTVGVVDPSEAEPIIDSLKRSGRNLTYILNTHHHYDHTGG------NLELKDRYGAKV 74 Query: 104 LPRNPQREEIIGNGEQQYVYLKDGDVIKTEGATLRVLYTPGHTDDHMALLLEEENAIFSG 163 + ++ I G + LKDGD G + V+ TPGHT H++L AIF+G Sbjct: 75 IGSAMDKDRIPGID----MALKDGDKWMFAGHEVHVMDTPGHTKGHISLYFPGSRAIFTG 130 Query: 164 DCILG-EGTTVFEDLYDYM-NSLKELLKIKADI-IYPGHGPVIHNAEAK---------IQ 211 D + +FE M SL+++ + D IY GH + N++ +Q Sbjct: 131 DTMFSLSCGKLFEGTPKQMLASLQKITSLPDDTSIYCGHEYTLSNSKFALSLEPNNEVLQ 190 Query: 212 QYISH-RNIREQQILTL 227 Y +H +R +++ T+ Sbjct: 191 SYAAHVAELRSKKLPTI 207 >6N36-A nrPDB Length = 271 Score = 156 bits (394), Expect = 1e-38, Method: Composition-based stats. Identities = 40/191 (20%), Positives = 75/191 (39%), Gaps = 25/191 (13%) Query: 34 YLVGTGPRRILIDTGEPAIPEYISCLKQALTEFNTAIQEIVVTHWHRDHSGGIGDIC--- 90 +L+ T ILI+TG I + L I+ ++ TH H DH G + + Sbjct: 40 FLITTPKGHILINTGVAGSDTLIKAHMKTLGFKFKDIRILLTTHAHYDHVGAMAAVKQQT 99 Query: 91 --KSINNDTTYCIKKLPRNPQREEIIGNGEQQYVYLK------DGDVIKTEGATLRVLYT 142 K + N+ + L + ++G ++ +K DGD I+ G + + Sbjct: 100 HAKMMVNEKDAAL--LADGGNSDYVMGGKGSMFLPVKADRLLHDGDSIQLGGMKIVMRQH 157 Query: 143 PGHTDDHMALLLEEENAIFSGDCILGEGTTVFEDL------------YDYMNSLKELLKI 190 PGHT + L + ++A+ + ++ ++ D DY +LK + + Sbjct: 158 PGHTPGANSFLFDVKDAVRTYKVLIANIPSILNDTKLSGMPLYPEVGKDYAYTLKAMKAL 217 Query: 191 KADIIYPGHGP 201 K D+ H Sbjct: 218 KFDLWLAPHAG 228 >3ADR-A nrPDB Length = 261 Score = 146 bits (368), Expect = 9e-36, Method: Composition-based stats. Identities = 50/233 (21%), Positives = 99/233 (42%), Gaps = 50/233 (21%) Query: 24 GPMTLQGTNTYLVGTGPR-RILIDTGEPAIPEYISCLKQALTEFN--TAIQEIVVTHWHR 80 GP+ T V G + ++ID G + ++ +F+ + IV+TH H Sbjct: 12 GPVEFPEIATVYVMCGEKLTVMIDAG----------VSNSIADFSFLDKLDYIVLTHLHI 61 Query: 81 DHSGGIGDICKSINNDTTY------------CIKKLPRNPQREEIIGN------------ 116 DH G + ++ + +KKL N E+++G+ Sbjct: 62 DHIGLLPELLQVYKAKVLVKSGFKKYLTSEDGLKKL--NESAEKVLGDLYYVYGGLEKKL 119 Query: 117 GEQQYVYLKDGDVIKTEGATLRVLYTPGHTDDHMALLLEEENAIFSGDC-------ILGE 169 + + + ++ + G +R++YTPGH HM++L+++ +F+GD ++ Sbjct: 120 DQDKVIEVEGNEEFDLGGYRMRLIYTPGHARHHMSVLVDD--FLFTGDSAGAYFNGVVIP 177 Query: 170 GTTVFEDLYDYMNSLKELLKIKADIIYPGHGPVIHN--AEAKIQQYISHRNIR 220 T D YM SLK +++K ++ HG ++ E ++Q +S I+ Sbjct: 178 TTPPVIDYKMYMESLKRQIELKPKVVGFAHGGLVSPKIMEEHLKQMLSKEEIQ 230 >2OHJ-A nrPDB Length = 404 Score = 146 bits (367), Expect = 1e-35, Method: Composition-based stats. Identities = 50/179 (27%), Positives = 81/179 (45%), Gaps = 10/179 (5%) Query: 27 TLQGT--NTYLVGTGPRRILIDTGEPAI-PEYISCLKQALTEFNT-AIQEIVVTHWHRDH 82 TLQGT N YLV LID P E ++ ++ AL + + I+ H +DH Sbjct: 29 TLQGTTYNAYLVCGDEGVALIDNSYPGTFDELMARVEDALQQVGMERVDYIIQNHVEKDH 88 Query: 83 SGGIGDICKSINNDTTYCIKKLPRNPQREEIIGNGEQQYVYLKDGDVIKTEGATLRVLYT 142 SG + ++ + YC + + + E +++ +K GDV+ G TL L T Sbjct: 89 SGVLVELHRRFPEAPIYCTEVAVKGLLKHYPSL-REAEFMTVKTGDVLDLGGKTLTFLET 147 Query: 143 P-GHTDDHMALLLEEENAIFSGDCI---LGEGTTVFEDLYDYMNSLKELLKIKADIIYP 197 P H D M LL+E+ +FS D L + ++ +Y+ + K A++I P Sbjct: 148 PLLHWPDSMFTLLDEDGILFSNDAFGQHLCCPQRLDREIPEYI-LMDAARKFYANLITP 205 >4CHL-A nrPDB Length = 238 Score = 141 bits (355), Expect = 3e-34, Method: Composition-based stats. Identities = 50/181 (27%), Positives = 79/181 (43%), Gaps = 28/181 (15%) Query: 31 TNTYLVGTGPRR--ILIDTGEPAIPEYISCLKQALTEFNTAIQEIVVTHWHRDHSGGIGD 88 T TYL+G R +LID P Q + E + V TH H DH G G Sbjct: 19 TFTYLLGDRESREAVLIDPVLETAPRD----AQLIKELGLRLLYAVNTHCHADHITGSG- 73 Query: 89 ICKSINNDTTYCIKKLPRNPQREEIIGNGEQQYVYLKDGDVIKTEGATLRVLYTPGHTDD 148 + +S+ I +L +G Q ++++DGD I+ L +PGHT Sbjct: 74 LLRSLLPGCQSVISRL-----------SGAQADLHIEDGDSIRFGRFALETRASPGHTPG 122 Query: 149 HMALLLEEENAIFSGDCIL--GEGTTVFED-----LYDYMNSLKELLKIKAD-IIYPGHG 200 + +L + + F+GD +L G G T F+ LY ++ +++ + D +IYP H Sbjct: 123 CVTFVLNDHSMAFTGDALLIRGCGRTDFQQGCAKTLYHSVH--EKIFTLPGDCLIYPAHD 180 Query: 201 P 201 Sbjct: 181 Y 181 >6FRM-A nrPDB Length = 410 Score = 132 bits (332), Expect = 2e-31, Method: Composition-based stats. Identities = 43/146 (29%), Positives = 56/146 (38%), Gaps = 7/146 (4%) Query: 27 TLQGT--NTYLVGTGPRRILIDTGEPAIPEYI-SCLKQALTEFNT--AIQEIVVTHWHRD 81 TL GT N YLV + LID P + +K A + I IV H +D Sbjct: 29 TLNGTTYNAYLVFGDDKVALIDNTYPGTSAQMWGRIKDACEKEGREFKIDVIVQNHVEKD 88 Query: 82 HSGGIGDICKSINNDTTYCIKKLPRNPQREEIIGNGEQQYVYLKDGDVIKTEGATLRVLY 141 HSG + +I K YC + + G + +K + I G TL L Sbjct: 89 HSGALPEIHKKFPEAPIYCTEVAVEGLVKHFPSLKG-APFKVVKSLESIDLGGKTLTFLE 147 Query: 142 TP-GHTDDHMALLLEEENAIFSGDCI 166 P H D M L EE +FS D Sbjct: 148 APLLHWPDSMFTLYAEEGILFSNDAF 173 >6DJA-A nrPDB Length = 222 Score = 131 bits (328), Expect = 5e-31, Method: Composition-based stats. Identities = 41/183 (22%), Positives = 85/183 (46%), Gaps = 21/183 (11%) Query: 31 TNTYLVGTGPRRILIDTG--EPAIPEYISCLKQALTEFNTAIQEIVVTHWHRDHSGGIGD 88 +N ++ T +L+D+ + E I +++ +F + ++++TH H D GG+ Sbjct: 36 SNGLVLNTSKGLVLVDSSWDDKLTKELIEMVEK---KFKKRVTDVIITHAHADRIGGMKT 92 Query: 89 IC-KSINNDTTYCIKKLPRNPQREEIIGNGEQQYVYLKDGDVIKTEGATLRVLYTPGHTD 147 + + I +T +L + EE +G+ Q LK G++ GHT+ Sbjct: 93 LKERGIKAHSTALTAELAKKNGYEEPLGD-LQSVTNLKFGNM-----KVETFYPGKGHTE 146 Query: 148 DHMALLLEEENAIFSGDCILGEGTTV----FEDLY--DYMNSLKELLKIKADI--IYPGH 199 D++ + L + + +G C++ ++ D Y ++ S++ +LK +I + PGH Sbjct: 147 DNIVVWLPQYQIL-AGGCLVKSASSKDLGNVADAYVNEWSTSIENVLKRYGNINLVVPGH 205 Query: 200 GPV 202 G V Sbjct: 206 GEV 208 >1X8H-A nrPDB Length = 228 Score = 129 bits (325), Expect = 9e-31, Method: Composition-based stats. Identities = 44/198 (22%), Positives = 76/198 (38%), Gaps = 31/198 (15%) Query: 32 NTYLVGTGPRRILIDTGEPAIPEYISCLKQALTEFNTA-IQEIVVTHWHRDHSGGIG--- 87 N+ + ++ G P+ L + + + + E++ T++H D +GG Sbjct: 24 NSMVYFGAKGVTVV--GATWTPDTARELHKLIKRVSRKPVLEVINTNYHTDRAGGNAYWK 81 Query: 88 -------------DICKSINND-TTYCIKKLPRNPQREEIIGNGEQQYVYLKDGDVIKTE 133 D+ KS + + K LP P ++ N + DGD E Sbjct: 82 SIGAKVVSTRQTRDLMKSDWAEIVAFTRKGLPEYPDLPLVLPN------VVHDGDFTLQE 135 Query: 134 GATLRVLYTPGHTDDHMALLLEEENAIFSGDCILGE--GTTVFEDLYDYMNSLKEL--LK 189 G P HT D + + +E ++ G CIL E G F D+ Y +L+ L +K Sbjct: 136 GKVRAFYAGPAHTPDGIFVYFPDEQVLY-GGCILKEKLGNLSFADVKAYPQTLERLKAMK 194 Query: 190 IKADIIYPGHGPVIHNAE 207 + + GH +H E Sbjct: 195 LPIKTVIGGHDSPLHGPE 212 >2UYX-A nrPDB Length = 228 Score = 121 bits (302), Expect = 5e-28, Method: Composition-based stats. Identities = 42/183 (22%), Positives = 83/183 (45%), Gaps = 21/183 (11%) Query: 31 TNTYLVGTGPRRILIDTG--EPAIPEYISCLKQALTEFNTAIQEIVVTHWHRDHSGGIGD 88 +N ++ T +L+D+ + E I +++ +F + ++++TH H GGI Sbjct: 42 SNGLVLNTSKGLVLVDSSWDDKLTKELIEMVEK---KFQKRVTDVIITHAHASRIGGIKT 98 Query: 89 IC-KSINNDTTYCIKKLPRNPQREEIIGNGEQQYVYLKDGDVIKTEGATLRVLYTPGHTD 147 + + I +T +L + EE +G+ Q LK G++ GHT+ Sbjct: 99 LKERGIKAHSTALTAELAKKNGYEEPLGD-LQTVTNLKFGNM-----KVETFYPGKGHTE 152 Query: 148 DHMALLLEEENAIFSGDCILGEGTTV----FEDLY--DYMNSLKELLKIKADI--IYPGH 199 D++ + L + N + G C++ + D Y ++ S++ +LK +I + PGH Sbjct: 153 DNIVVWLPQYNIL-VGGCLVKSTSAKDLGNVADAYVNEWSTSIENVLKRYRNINAVVPGH 211 Query: 200 GPV 202 G V Sbjct: 212 GEV 214 >6ETB-A nrPDB Length = 412 Score = 88.3 bits (217), Expect = 4e-18, Method: Composition-based stats. Identities = 41/177 (23%), Positives = 69/177 (38%), Gaps = 10/177 (5%) Query: 27 TLQGT--NTYLVGTGPRRILIDTGEPAIPEYISCLKQALTEFNTAIQEIVVTHWHRDHSG 84 TL+G+ N+YL+ + +LIDT + + + I IV+ H DH+G Sbjct: 29 TLRGSSYNSYLIR-EEKNVLIDTVDHKFSREFVQNLRNEIDLA-DIDYIVINHAEEDHAG 86 Query: 85 GIGDICKSINNDTTYCIKKLPRNPQREEIIGNGEQQYVYLKDGDVIKTE-GATLRVLYTP 143 + ++ I + YC + E + +K GD + G L + TP Sbjct: 87 ALTELMAQIPDTPIYCTANAIDSINGHHHHP--EWNFNVVKTGDTLDIGNGKQLIFVETP 144 Query: 144 -GHTDDHMALLLEEENAIFSGDCILG--EGTTVFEDLYDYMNSLKELLKIKADIIYP 197 H D M L + +FS D +F D D ++ + A+I+ P Sbjct: 145 MLHWPDSMMTYLTGDAVLFSNDAFGQHYCDEHLFNDEVDQTELFEQCQRYYANILTP 201 >4D02-A nrPDB Length = 479 Score = 88.3 bits (217), Expect = 4e-18, Method: Composition-based stats. Identities = 41/177 (23%), Positives = 69/177 (38%), Gaps = 10/177 (5%) Query: 27 TLQGT--NTYLVGTGPRRILIDTGEPAIPEYISCLKQALTEFNTAIQEIVVTHWHRDHSG 84 TL+G+ N+YL+ + +LIDT + + + I IV+ H DH+G Sbjct: 29 TLRGSSYNSYLIR-EEKNVLIDTVDHKFSREFVQNLRNEIDLA-DIDYIVINHAEEDHAG 86 Query: 85 GIGDICKSINNDTTYCIKKLPRNPQREEIIGNGEQQYVYLKDGDVIKTE-GATLRVLYTP 143 + ++ I + YC + E + +K GD + G L + TP Sbjct: 87 ALTELMAQIPDTPIYCTANAIDSINGHHHHP--EWNFNVVKTGDTLDIGNGKQLIFVETP 144 Query: 144 -GHTDDHMALLLEEENAIFSGDCILG--EGTTVFEDLYDYMNSLKELLKIKADIIYP 197 H D M L + +FS D +F D D ++ + A+I+ P Sbjct: 145 MLHWPDSMMTYLTGDAVLFSNDAFGQHYCDEHLFNDEVDQTELFEQCQRYYANILTP 201 >1YCF-A nrPDB Length = 398 Score = 86.4 bits (212), Expect = 1e-17, Method: Composition-based stats. Identities = 39/180 (21%), Positives = 67/180 (37%), Gaps = 9/180 (5%) Query: 23 PGPMTLQGT--NTYLVGTGPRRILIDTGEPAIPEYISCLKQALTEFNTAIQEIVVTHWHR 80 P T +GT N YL+ + L+DT E + + + + + +VV H Sbjct: 26 PAFSTHRGTTYNAYLIV-DDKTALVDTVYEPFKEELIAKLKQIKD-PVKLDYLVVNHTES 83 Query: 81 DHSGGIGDICKSINNDTTYCIKKLPRNPQREEIIGNGEQQYVYLKDGDVIKTEGATLRVL 140 DH+G I + + C ++ + + + Y +K G + +L + Sbjct: 84 DHAGAFPAIMELCPDAHVLCTQRAFDSLKAHYSHIDFN--YTIVKTGTSVSLGKRSLTFI 141 Query: 141 YTP-GHTDDHMALLLEEENAIFSGDCILGEGTTV--FEDLYDYMNSLKELLKIKADIIYP 197 P H D M + EE + D T F+D D + E K A+I+ P Sbjct: 142 EAPMLHWPDSMFTYVPEEALLLPNDAFGQHIATSVRFDDQVDAGLIMDEAAKYYANILMP 201 >2QED-A nrPDB Length = 258 Score = 81.0 bits (198), Expect = 5e-16, Method: Composition-based stats. Identities = 43/214 (20%), Positives = 80/214 (37%), Gaps = 33/214 (15%) Query: 28 LQGTNTYLVGTGPRR-ILIDTGEPAIPEYISCLKQALTEFNTAIQEIVVTHWHRDHSGGI 86 Q +++ R +++D G + + +A+ E + I +TH H DH GG+ Sbjct: 16 FQDNYIWVLTNDEGRCVIVDPG------EAAPVLKAIAEHKWMPEAIFLTHHHHDHVGGV 69 Query: 87 GDICKSINNDTTYCIKKLPRNPQREEIIGNGEQQYVYLKDGDVIKTEGATLRVLYTPGHT 146 ++ + T Y + + DGD I+ G + TPGHT Sbjct: 70 KELLQHFPQMTVYGPAETQDKGATHL-----------VGDGDTIRVLGEKFTLFATPGHT 118 Query: 147 DDHMALLLEEENAIFSGDCIL-GEGTTVFEDLYDYMN-SLKELLKIKADIIY-PGHGPVI 203 H+ +F GD + G +FE M SL ++ + D + H + Sbjct: 119 LGHVCYF--SRPYLFCGDTLFSGGCGRLFEGTPSQMYQSLMKINSLPDDTLICCAHEYTL 176 Query: 204 HNAEAKI----------QQYISHRNIREQQILTL 227 N + + + Y + +R ++ +TL Sbjct: 177 ANIKFALSILPHDSFINEYYRKVKELRVKKQMTL 210 >3SD9-A nrPDB Length = 233 Score = 80.2 bits (196), Expect = 9e-16, Method: Composition-based stats. Identities = 42/200 (21%), Positives = 76/200 (38%), Gaps = 35/200 (17%) Query: 32 NTYLVGTGPRRILIDTGEPAIPEYISCLKQALTEFN-TAIQEIVVTHWHRDHSGGIG--- 87 N+ + +I G PE L + + + + I E++ T++H D +GG Sbjct: 27 NSMVYIGTDGITII--GATWTPETAETLYKEIRKVSPLPINEVINTNYHTDRAGGNAYWK 84 Query: 88 -------------DICKSINND-TTYCIKKLPRNPQREEIIGNGEQQYVYLKDGDVIKTE 133 D+ KS + + + P E+ + + GD Sbjct: 85 TLGAKIVATQMTYDLQKSQWGSIVNFTRQGNNKYPNLEKSLPDTVFP------GDFNLQN 138 Query: 134 GATLRVLYTPGHTDDHMALLLEEENAIFSGDCILGE--GTTVFEDLYDYMNSLKELL--- 188 G+ + HT D + + E ++ G+CIL E G F + +Y +L++L Sbjct: 139 GSIRAMYLGEAHTKDGIFVYFPAERVLY-GNCILKENLGNMSFANRTEYPKTLEKLKGLI 197 Query: 189 ---KIKADIIYPGHGPVIHN 205 ++K D I GH IH+ Sbjct: 198 EQGELKVDSIIAGHDTPIHD 217 >1E5D-A nrPDB Length = 402 Score = 79.4 bits (194), Expect = 1e-15, Method: Composition-based stats. Identities = 39/241 (16%), Positives = 79/241 (32%), Gaps = 34/241 (14%) Query: 32 NTYLVGTGPRRILIDTGEPAIPEYISCLKQALTEFNTAIQEIVVTHWHRDHSGGIGDICK 91 N YLV + L DT + + C ++ + I +V+ H DH+G + + + Sbjct: 36 NAYLV-EDEKTTLFDTVKAEYKGELLCGIASVID-PKKIDYLVIQHLELDHAGALPALIE 93 Query: 92 SINNDTTYCIKKLPRNPQREEIIGNGEQQYVYLKDGDVIKTEGATLRVLYTP-GHTDDHM 150 + + + + + + +K G+ + T+ T H D M Sbjct: 94 ACQPEKIFTSSLGQKAMESHFHYKDW--PVQVVKHGETLSLGKRTVTFYETRMLHWPDSM 151 Query: 151 ALLLEEENAIFSGDCILGE--GTTVFEDL-------------------YDYMNSLKELLK 189 +E + S D + F D +LK + Sbjct: 152 VSWFADEKVLISNDIFGQNIAASERFSDQIPVHTLERAMREYYANIVNPYAPQTLKAIET 211 Query: 190 I-----KADIIYPGHGPVIHNAE---AKIQQYISHRNIREQQILTLFRENFEKSFTVMEL 241 + + I P HG + A+ +Q+Y+ + + + +F ++ S M Sbjct: 212 LVGAGVAPEFICPDHGVIFRGADQCTFAVQKYVEYAEQKPTNKVVIFYDSMWHSTEKMAR 271 Query: 242 V 242 V Sbjct: 272 V 272 >1QH5-A nrPDB Length = 260 Score = 75.6 bits (184), Expect = 2e-14, Method: Composition-based stats. Identities = 43/206 (20%), Positives = 76/206 (36%), Gaps = 29/206 (14%) Query: 28 LQGTNTYLVGTGPRR--ILIDTGEPAIPEYISCLKQALTEFNTAIQEIVVTHWHRDHSGG 85 L YLV + ++D +P + A + + ++ TH H DH+GG Sbjct: 9 LTDNYMYLVIDDETKEAAIVDPVQP------QKVVDAARKHGVKLTTVLTTHHHWDHAGG 62 Query: 86 IGDICKSINNDTTYCIKKLPRNPQREEIIGNGEQQYVYLKDGDVIKTEGATLRVLYTPGH 145 + K L + I G + +L ++ ++ L TP H Sbjct: 63 NEKLVK--------LESGLKVYGGDDRI-GALTHKITHLST---LQVGSLNVKCLATPCH 110 Query: 146 TDDHMALLLEEEN-----AIFSGDC-ILGEGTTVFEDLYDYM--NSLKELLKIKADI-IY 196 T H+ + + A+F+GD + +E D M L+ L ++ D +Y Sbjct: 111 TSGHICYFVSKPGGSEPPAVFTGDTLFVAGCGKFYEGTADEMCKALLEVLGRLPPDTRVY 170 Query: 197 PGHGPVIHNAEAKIQQYISHRNIREQ 222 GH I+N + + IRE+ Sbjct: 171 CGHEYTINNLKFARHVEPGNAAIREK 196 >2Y8B-A nrPDB Length = 265 Score = 72.1 bits (175), Expect = 2e-13, Method: Composition-based stats. Identities = 31/184 (16%), Positives = 69/184 (37%), Gaps = 13/184 (7%) Query: 27 TLQGTNTYLVGTGPRRILIDTGEPAIPEYISCLKQALTEFNTAIQEIVVTHWHRDHSGGI 86 T+ +N +V +LIDT ++ L + + + + TH+H D GG+ Sbjct: 64 TVYSSNGLIVRDADELLLIDTAW-GAKNTVALLAEIEKQIGLPVTRSISTHFHDDRVGGV 122 Query: 87 GDICKSINNDTTY-CIKKLPRNPQREEIIGNGEQQYVYLKDGDVIKTEGATLRVLYTPGH 145 + + T ++L E + + GDV++ + H Sbjct: 123 DVLRAAGVATYTSPLTRQLAEAAGNEVPAHSLKALS---SSGDVVRFGPVEV-FYPGAAH 178 Query: 146 TDDHMALLLEEENAIFSGDCIL-----GEGTTVFEDLYDYMNSLKELLKIKA--DIIYPG 198 + D++ + + +F G + G +L ++ ++K + + +++ PG Sbjct: 179 SGDNLVVYVPAVRVLFGGCAVHEASRESAGNVADANLAEWPATIKRIQQRYPEAEVVIPG 238 Query: 199 HGPV 202 HG Sbjct: 239 HGLP 242 >2YNV-A nrPDB Length = 233 Score = 71.7 bits (174), Expect = 3e-13, Method: Composition-based stats. Identities = 45/207 (21%), Positives = 76/207 (36%), Gaps = 21/207 (10%) Query: 28 LQGTNTYLVGTGPRRILIDTGEPAIPEYISCLKQALTEFNTAIQEIVVTHWHRDHSGGIG 87 L +N +V + +IDT P E L T+ + + TH H D + GI Sbjct: 30 LVDSNGLVVLDNNQAYIIDT--PWSEEDTKLLLSWATDRGYQVMASISTHSHEDRTAGIK 87 Query: 88 DI-CKSINNDTTYCIKKLPRNPQREEIIGNGEQQYVYLKDGDVIKTEGATLRVLYTPGHT 146 + KSI T+ KKL + Y KD + G GHT Sbjct: 88 LLNSKSIPTYTSELTKKLLAREGKPVPTH-------YFKDDEFTLGNGLIELYYPGAGHT 140 Query: 147 DDHMALLLEEENAIFSGDCILGE------GTTVFEDLYDYMNSLKEL--LKIKADIIYPG 198 +D++ L + +F G C++ G + + +S+K + K ++ PG Sbjct: 141 EDNIVAWLPKSKILF-GGCLVRSHEWEGLGYVGDASISSWADSIKNIVSKKYPIQMVVPG 199 Query: 199 HGPVIHNAEAKIQQYISHRNIREQQIL 225 HG V + + I +++ Sbjct: 200 HGKV--GSSDILDHTIDLAESASNKLM 224 >5HH5-A nrPDB Length = 271 Score = 71.0 bits (172), Expect = 5e-13, Method: Composition-based stats. Identities = 33/189 (17%), Positives = 66/189 (34%), Gaps = 21/189 (11%) Query: 33 TYLVGTGPRRILIDTGEPAIPEYISCLKQALTEFNTAIQEIVVTHWHRDHSGGIGDICKS 92 LV T +L+D G P + ++ +A ++ I+++H H DH+G + ++ + Sbjct: 42 ALLVQTPDGAVLLDGGMPQMASHLLDNMKARGVTPRDLRLILLSHAHADHAGPVAELKRR 101 Query: 93 INNDTTYCIKK---LPRNPQREEIIGNG-----EQQYVYLKDGDVIKTEGATLRVLYTPG 144 + L R + G+G + DG+VI G + G Sbjct: 102 TGAKVAANAESAVLLARGGSDDLHFGDGITYPPANADRIVMDGEVITVGGIVFTAHFMAG 161 Query: 145 HTDDHMALLLEEEN-----AIFSGDCILGEGTTVFEDLYDYMNSLKE-------LLKIKA 192 HT A + I D + G + Y + +++ + + Sbjct: 162 HTPGSTAWTWTDTRNGKPVRIAYADSLSAPG-YQLQGNPRYPHLIEDYRRSFATVRALPC 220 Query: 193 DIIYPGHGP 201 D++ H Sbjct: 221 DVLLTPHPG 229 >2P18-A nrPDB Length = 311 Score = 68.7 bits (166), Expect = 3e-12, Method: Composition-based stats. Identities = 51/267 (19%), Positives = 94/267 (35%), Gaps = 45/267 (16%) Query: 27 TLQGTNTYLVGTGPRRIL--IDTGEPAIPEYISCLKQALTEFNTAIQE----IVVTHWHR 80 TL+ +YL+ L +D P + + N + I+ TH H Sbjct: 36 TLKDNFSYLINDHTTHTLAAVDVNADYKPILTYIEEHLKQQGNADVTYTFSTILSTHKHW 95 Query: 81 DHSGGIGDICKSINNDTTYCIKKLPRNPQREEIIGNGEQQYVYLKDGDVIKTEGATLRVL 140 DHSGG + K+ + + + I +++GD ++ ++ V+ Sbjct: 96 DHSGGNAKL-KAELEAMNSTVPVVVVGGANDSIP----AVTKPVREGDRVQVGDLSVEVI 150 Query: 141 YTPGHTDDHMALLL------EEENAIFSGDCILGEGTTVF--EDLYDYMNSLKELLKI-- 190 P HT H+ + + A+F+GD + G F D D +++++ I Sbjct: 151 DAPCHTRGHVLYKVQHPQHPNDGVALFTGDTMFIAGIGAFFEGDEKDMCRAMEKVYHIHK 210 Query: 191 -------KADIIYPGHGPVIHNAEAKIQQYISHRN-----IREQQILTLFRENFEKSFTV 238 K I+PGH + + + I+ Q R + + Sbjct: 211 GNDYALDKVTFIFPGHEYTSGFMTFSEKTFPDRASDDLAFIQAQ------RAKYAAA--- 261 Query: 239 MELVKIIYKNTPENLHEMAKHNLLLHL 265 VK + P +L E + NL L + Sbjct: 262 ---VKTGDPSVPSSLAEEKRQNLFLRV 285 >2Q0J-A nrPDB Length = 321 Score = 67.9 bits (164), Expect = 5e-12, Method: Composition-based stats. Identities = 34/167 (20%), Positives = 63/167 (37%), Gaps = 30/167 (17%) Query: 69 AIQEIVVTHWHRDHSGGIGDICKSINNDTTYCIKK---------------------LPRN 107 + ++TH H DH G + +C + N ++ L Sbjct: 81 QVHYWLITHKHYDHCGLLPYLCPRLPNVQVLASERTCQAWKSESAVRVVERLNRQLLRAE 140 Query: 108 PQREEIIGNGEQQYVYLKDGDVIKTE-GATLRVLYTPGHTDDHMALLLEEENAIFSGDCI 166 + E + DG+ ++ L+V+ GH+DDH+ +F GD + Sbjct: 141 QRLPEACAWDALPVRAVADGEWLELGPRHRLQVIEAHGHSDDHVVFYDVRRRRLFCGDAL 200 Query: 167 --LGEG-----TTVFEDLYDYMNSLKELLKIKADI-IYPGHGPVIHN 205 E VF+D+ Y+ SL+ L ++ + + PGHG ++ Sbjct: 201 GEFDEAEGVWRPLVFDDMEAYLESLERLQRLPTLLQLIPGHGGLLRG 247 >4F6Z-A nrPDB Length = 236 Score = 67.1 bits (162), Expect = 8e-12, Method: Composition-based stats. Identities = 39/199 (19%), Positives = 70/199 (35%), Gaps = 14/199 (7%) Query: 33 TYLVGTGPRRILIDTGEPAIPEYISCLKQALTEFNTAIQEIVVTHWHRDHSGGIGDI-CK 91 +V LIDT P + L E I+ + +H+H D +GGI + + Sbjct: 35 GLVVLVNAEAYLIDT--PFTAKDTEKLVTWFVERGYKIKGSISSHFHSDSTGGIEWLNSR 92 Query: 92 SINNDTTYCIKKLPRNPQREEIIGNGEQQYVYLKDGDVIKTEGATLRVLYTPGHTDDHMA 151 SI + +L + + Q + + PGHT D++ Sbjct: 93 SIPTYASELTNELLKKDGK-------VQATNSFSGVNYWLVKNKIEVFYPGPGHTPDNVV 145 Query: 152 LLLEEENAIFSGDCI--LGEGTTVFEDLYDYMNSLKELLKIKA--DIIYPGHGPVIHNAE 207 + L E +F G I G G ++ + S K L ++ P H V + Sbjct: 146 VWLPERKILFGGGFIKPYGLGNLGDANIEAWPKSAKLLKSKYGKAKLVVPSHSEVGDASL 205 Query: 208 AKIQQYISHRNIREQQILT 226 K+ + + + E + + Sbjct: 206 LKLTLEQAVKGLNESKKPS 224 >3ZNB-A nrPDB Length = 232 Score = 66.7 bits (161), Expect = 1e-11, Method: Composition-based stats. Identities = 41/200 (20%), Positives = 80/200 (40%), Gaps = 26/200 (13%) Query: 31 TNTYLVGTGPRRILIDT--GEPAIPEYISCLKQALTEFNTAIQEIVVTHWHRDHSGGIGD 88 +N +V + L+DT + ++ + +L + + HWH D GG+G Sbjct: 37 SNGMIVINNHQAALLDTPINDAQTETLVNWVADSLH---AKVTTFIPNHWHGDCIGGLGY 93 Query: 89 ICKSINNDTTYCIKKLPRNPQREEIIGNGEQQYVYLKDGDVIKTEGATLRVLY-TPGHTD 147 + K ++ + +E+ + E + D + +G L+ Y GH Sbjct: 94 LQKK---GVQSYANQMTIDLAKEKGLPVPEHGFT---DSLTVSLDGMPLQCYYLGGGHAT 147 Query: 148 DHMALLLEEENAIFSGDCILGE------GTTVFEDLYDYMNSLKELLKIKADI--IYPGH 199 D++ + L EN +F G C+L + G D+ + +L ++ + PGH Sbjct: 148 DNIVVWLPTENILF-GGCMLKDNQATSIGNISDADVTAWPKTLDKVKAKFPSARYVVPGH 206 Query: 200 G-----PVIHNAEAKIQQYI 214 G +I + + + QYI Sbjct: 207 GDYGGTELIEHTKQIVNQYI 226 >4BP0-A nrPDB Length = 250 Score = 66.0 bits (159), Expect = 2e-11, Method: Composition-based stats. Identities = 33/201 (16%), Positives = 68/201 (33%), Gaps = 31/201 (15%) Query: 28 LQGTNTYLVGTGPRRILIDTG---EPAIPEYISCLKQALTEFNTAIQEIVVTHWHRDHSG 84 +N + ++I + + + + + + TH+H D +G Sbjct: 31 FYSSNVLVAKMLDGTVVIVSSPFENLGTQTLMDWVAKTMKPKKV---VAINTHFHLDGTG 87 Query: 85 G------------IGDICKSI----NNDTTYCIKKLPRNPQREEIIGNG----EQQYVYL 124 G D+ K + N + +N + I + L Sbjct: 88 GNEIYKKMGAETWSSDLTKQLRLEENKKDRIKAAEFYKNEDLKRRILSSHPVPADNVFDL 147 Query: 125 KDGDVIKTEGATLRV-LYTPGHTDDHMALLLEEENAIFSGDCILGEGTTVF---EDLYDY 180 K G V + V P H+ D++ + ++ +F G C++ + ++ + Sbjct: 148 KQGKVFSFSNELVEVSFPGPAHSPDNVVVYFPKKKLLF-GGCMIKPKELGYLGDANVKAW 206 Query: 181 MNSLKELLKIKADIIYPGHGP 201 +S + L K A I+ PGHG Sbjct: 207 PDSARRLKKFDAKIVIPGHGE 227 >1M2X-A nrPDB Length = 223 Score = 65.2 bits (157), Expect = 3e-11, Method: Composition-based stats. Identities = 35/188 (18%), Positives = 65/188 (34%), Gaps = 23/188 (12%) Query: 27 TLQGT----NTYLVGTGPRRILIDTGEPAIPEYISCLKQALTEFNTAIQEIVVTHWHRDH 82 T GT N + T ++ID ++ S + + + + TH H D Sbjct: 19 TFNGTKYAANAVYLVTDKGVVVIDCPW-GEDKFKSFTDEIYKKHGKKVIMNIATHSHDDR 77 Query: 83 SGGIGDICKSINNDTTYCIKKLPRNPQREEIIGNGEQQYVYLKDGDVIKTEGATLRVLY- 141 +GG+ K TY K +E N + + K + +V Y Sbjct: 78 AGGLEYFGK--IGAKTYSTKMTDSILAKE----NKPRAQYTFDNNKSFKVGKSEFQVYYP 131 Query: 142 TPGHTDDHMALLLEEENAIFSGDCILGEGTTV---------FEDLYDYMNSLKELLKIKA 192 GHT D++ + +E + G CI+ + D ++++++ A Sbjct: 132 GKGHTADNVVVWFPKEKVL-VGGCIIKSADSKDLGYIGEAYVNDWTQSVHNIQQKFS-GA 189 Query: 193 DIIYPGHG 200 + GH Sbjct: 190 QYVVAGHD 197 >4UBQ-A nrPDB Length = 229 Score = 64.4 bits (155), Expect = 5e-11, Method: Composition-based stats. Identities = 42/191 (21%), Positives = 73/191 (38%), Gaps = 26/191 (13%) Query: 27 TLQGTNTYLVGTGPRRI--------LIDTGEPAIPEYISCLKQALTEFNTAIQEIVVTHW 78 + + N + V + + LIDT P L E I+ + +H+ Sbjct: 22 SFEEVNGWGVVSKHGLVVLVNTDAYLIDT--PFTATDTEKLVNWFVERGYKIKGTISSHF 79 Query: 79 HRDHSGGIGDI-CKSINNDTTYCIKKLPRNPQREEIIGNGEQQYVYLKDGDVIKTEGATL 137 H D +GGI + +SI + +L + +G+ Q G + Sbjct: 80 HSDSTGGIEWLNSQSIPTYASELTNELLKK--------DGKVQAKNSFSGVSYWLVKNKI 131 Query: 138 RVLY-TPGHTDDHMALLLEEENAIFSGDCILGE---GTTVFEDLYDYMNSLKELLK--IK 191 V Y PGHT D++ + L E+ +F G C + G +L + S K L+ +K Sbjct: 132 EVFYPGPGHTQDNVVVWLPEKKILF-GGCFVKPDGLGNLGDANLEAWPKSAKILMSKYVK 190 Query: 192 ADIIYPGHGPV 202 A ++ H + Sbjct: 191 AKLVVSSHSEI 201 >4DIK-A nrPDB Length = 410 Score = 64.4 bits (155), Expect = 5e-11, Method: Composition-based stats. Identities = 50/222 (22%), Positives = 85/222 (38%), Gaps = 39/222 (17%) Query: 32 NTYLVGTGPRRILIDTGEPA--IPEYISCLKQALTEFNTAIQEIVVTHWHRDHSGGIGDI 89 N YLV +LID G E+I L + + I I+V H D SG + Sbjct: 53 NAYLVKLNGANVLID-GWKGNYAKEFIDALSKIVDP--KEITHIIVNHTEPDASGSLPAT 109 Query: 90 CKSINNDTTYCIKKLPRNPQREEIIG-NGEQQYVYLKDGDVIKTEGATLRVLYTP-GHTD 147 K+I +D ++ + N + + G G + +KDG+ + G + + TP H Sbjct: 110 LKTIGHD----VEIIASNFGKRLLEGFYGIKDVTVVKDGEEREIGGKKFKFVMTPWLHWP 165 Query: 148 DHMALLLEEENAIFSGDC--------ILGEGTTVFEDLY-------------DYMNSL-- 184 D M L+ +FS D IL + + Y Y N + Sbjct: 166 DTMVTYLD--GILFSCDVGGGYLLPEILDDSNESVVERYLPHVTKYIVTVIGHYKNYILE 223 Query: 185 --KELLKIKADIIYPGHGPVI-HNAEAKIQQYISHRNIREQQ 223 ++L +K + PGHG + + + + Y+S ++ Sbjct: 224 GAEKLSSLKIKALLPGHGLIWKKDPQRLLNHYVSVAKGDPKK 265 >2Q9U-A nrPDB Length = 414 Score = 63.7 bits (153), Expect = 1e-10, Method: Composition-based stats. Identities = 28/136 (20%), Positives = 52/136 (38%), Gaps = 5/136 (3%) Query: 32 NTYLVGTGPRRILIDTGEPAIPEYISCLKQALTEFNTAIQEIVVTHWHRDHSGGIGDICK 91 N+Y + ++ P E++S + I+ +V+ H DH+ + D Sbjct: 42 NSYFIDDECPTVIDSVKYPFAEEWLSRIAACCPL--DKIKYVVMNHAEGDHASSLKDHYH 99 Query: 92 SINNDTTYCIKKLPRNPQREEIIGNGEQQYVYLKDGDVIKTEGATLRVLYTP-GHTDDHM 150 N T C KK + + + G + ++ + D +K TL+ + P H D Sbjct: 100 KFTNATFVCTKKCQEH--LKILYGMEKATWLIVDDKYTLKIGKRTLKFIPVPLLHWPDST 157 Query: 151 ALLLEEENAIFSGDCI 166 E+ +FS D Sbjct: 158 FTYCPEDKILFSNDGF 173 >3L6N-A nrPDB Length = 219 Score = 63.3 bits (152), Expect = 1e-10, Method: Composition-based stats. Identities = 32/180 (17%), Positives = 62/180 (34%), Gaps = 19/180 (10%) Query: 32 NTYLVGTGPRRILIDTGEPAIPEYISCLKQALTEF-NTAIQEIVVTHWHRDHSGGIGDIC 90 N+ + T +L D P L + + N + + TH H D +G + Sbjct: 32 NSMYLVTKKGVVLFD--VPWEKVQYQSLMDTIKKRHNLPVVAVFATHSHDDRAGDLSFF- 88 Query: 91 KSINNDTTYCIKKLPRNPQREEIIGNGEQQYVYLKDGDVIKTEGATLRV-LYTPGHTDDH 149 + TY K +++ +K G + G V GHT D+ Sbjct: 89 -NNKGIKTYATAKTNEFLKKD----GKATSTEIIKTGKPYRIGGEEFVVDFLGEGHTADN 143 Query: 150 MALLLEEENAIFSGDCILGE------GTTVFEDLYDYMNSLKELLKIKAD--IIYPGHGP 201 + + + N + G C++ G ++ + ++ +L + +I PGH Sbjct: 144 VVVWFPKYNVL-DGGCLVKSNSATDLGYIKEANVEQWPKTINKLKAKYSKATLIIPGHDE 202 >5B3R-A nrPDB Length = 228 Score = 60.2 bits (144), Expect = 9e-10, Method: Composition-based stats. Identities = 37/176 (21%), Positives = 60/176 (34%), Gaps = 16/176 (9%) Query: 33 TYLVGTGPRRILIDTGEPAIPEYISCLKQALTEFNTAIQEIVVTHWHRDHSGGIGDICKS 92 +V LIDT P + L E I+ + TH+H D + GI + Sbjct: 35 GLVVLVKNDAYLIDT--PITAKDTEKLVNWFIEHGYRIKGSISTHFHGDSTAGIEWLNSQ 92 Query: 93 INNDTTYCIKKLPRNPQREEIIGNGEQQYVYLKDGDVIKTEGATLRVLY-TPGHTDDHMA 151 I E + + + Q G + V Y PGHT D++ Sbjct: 93 -------SISTYASELTNELLKKDNKVQATNSFSGVSYSLIKNKIEVFYPGPGHTQDNVV 145 Query: 152 LLLEEENAIFSGDCILGE---GTTVFEDLYDYMNSLKELLKIKA--DIIYPGHGPV 202 + L E+ +F G C + G +L + S K L+ ++ H + Sbjct: 146 VWLPEKKILF-GGCFVKPDGLGNLGDANLEAWPKSAKILMSKYGKAKLVVSSHSEI 200 >5K4M-A nrPDB Length = 245 Score = 59.0 bits (141), Expect = 2e-09, Method: Composition-based stats. Identities = 30/169 (17%), Positives = 58/169 (34%), Gaps = 21/169 (12%) Query: 31 TNTYLVGTGPRRILIDTGEPAIPEYISCLKQALT-EFNTAIQEIVVTHWHRDHSGGIGDI 89 +N +V G R +++DT + + + + E N + VVTH H+D GG+ + Sbjct: 50 SNGLIVRDGGRVLMVDT--AGTDAQTAQILKWIKQEINLPVALAVVTHAHQDKMGGMDAL 107 Query: 90 CKSINNDTTYCIKKLPRNPQREEIIGNGEQQYVY------LKDGDVIKTEGATLRVLYTP 143 N Q + ++ + P Sbjct: 108 H----AAGIATYANALSNQLAPREGVVAAQHSLTFAATGWVEPATAPNFGPLKV-FYPGP 162 Query: 144 GHTDDHMALLLEEENAIFSGDCILGE------GTTVFEDLYDYMNSLKE 186 GHT D++ + ++ + F G C++ + G D Y S++ Sbjct: 163 GHTSDNITVGIDGTDIAF-GGCLIRDSKAKSLGNLDEADTEHYAASVRA 210 >3DHA-A nrPDB Length = 254 Score = 57.9 bits (138), Expect = 5e-09, Method: Composition-based stats. Identities = 50/217 (23%), Positives = 76/217 (35%), Gaps = 46/217 (21%) Query: 23 PGPMTLQGTNTYLVGTGPRRILIDTGEPAIP--------------------EYISCLKQA 62 PG + YL+ T IL+DTG P + Sbjct: 31 PGKLLNLPVWCYLLETEEGPILVDTGMPESAVNNEGLFNGTFVEGQILPKMTEEDRIVNI 90 Query: 63 LTEFN---TAIQEIVVTHWHRDHSGGIGDICKSINNDTTYCIKKLPRNPQREEIIGNGEQ 119 L + I+ +H H DH+GG G N + REE + Sbjct: 91 LKRVGYEPDDLLYIISSHLHFDHAGGNGAFT---NTPIIVQRTEYEAALHREEYMKECIL 147 Query: 120 QYVYLK--DGDVIKTEGATLRVLYTPGHTDDHMALLLEEEN---AIFSGDCILGEGTTVF 174 ++ K +GD G +++LYTPGH+ H +L +E E + + D F Sbjct: 148 PHLNYKIIEGDYEVVPG--VQLLYTPGHSPGHQSLFIETEQSGSVLLTIDA--SYTKENF 203 Query: 175 ED-----------LYDYMNSLKELLKIKADIIYPGHG 200 ED + LKE++K + II+ GH Sbjct: 204 EDEVPFAGFDPELALSSIKRLKEVVKKEKPIIFFGHD 240 >3IEL-A nrPDB Length = 431 Score = 53.3 bits (126), Expect = 1e-07, Method: Composition-based stats. Identities = 25/155 (16%), Positives = 52/155 (33%), Gaps = 20/155 (12%) Query: 27 TLQGTNTYLVGTGPRRILIDTGEPAIPEYISCLKQALTEFNTAIQEIVVTHWHRDHSGGI 86 + G+ L+ G RR+L+D G E + +++TH H DH G + Sbjct: 11 EVTGSAHLLLAGG-RRVLLDCGMFQGKEEARNHA-PFGFDPKEVDAVLLTHAHLDHVGRL 68 Query: 87 GDICKSINNDTTYCI-----------KKLPRNPQREEIIGNGEQQYV----YLKDGDVIK 131 + + Y + + ++ + L+ G+ ++ Sbjct: 69 PKLFREGYRGPVYATRATVLLMEIVLEDALKVMDEPFFGPEDVEEALGHLRPLEYGEWLR 128 Query: 132 TEGATLRVLYTPGHTDDHMALLLEEEN--AIFSGD 164 +L GH ++ + E ++SGD Sbjct: 129 LGALSLAFGQA-GHLPGSAFVVAQGEGRTLVYSGD 162 >5NBK-A nrPDB Length = 251 Score = 51.3 bits (121), Expect = 4e-07, Method: Composition-based stats. Identities = 26/153 (16%), Positives = 53/153 (34%), Gaps = 21/153 (13%) Query: 31 TNTYLVGTGPRRILIDTGEPAIPEYISCLKQALT-EFNTAIQEIVVTHWHRDHSGGIGDI 89 +N +V G R +++DT + + + + E N + VVTH H+D GG+ + Sbjct: 48 SNGLIVRDGGRVLVVDTAW--TDDQTAQILNWIKQEINLPVALAVVTHAHQDKMGGMDAL 105 Query: 90 CKSINNDTTYCIKKLPRNPQREEIIGNGEQQYVY---------LKDGDVIKTEGATLRVL 140 I + G + ++ + Sbjct: 106 H-------AAGIATYANALSNQLAPQEGMVAAQHSLTFAANGWVEPATAPNFGPLKV-FY 157 Query: 141 YTPGHTDDHMALLLEEENAIFSGDCILGEGTTV 173 PGHT D++ + ++ + F G C++ + Sbjct: 158 PGPGHTSDNITVGIDGTDIAF-GGCLIKDSKAK 189 >2XR1-A nrPDB Length = 640 Score = 50.9 bits (120), Expect = 6e-07, Method: Composition-based stats. Identities = 31/126 (24%), Positives = 43/126 (34%), Gaps = 18/126 (14%) Query: 14 RVVRVLGCNPGPMTLQGTNTYLVGTGPRRILIDTGE-PAIPEYISCLKQALTEFNTA-IQ 71 RV + GC G + +L+ T RILID G E ++ F I Sbjct: 185 RVTALGGCKE-----VGRSCFLLSTPESRILIDCGVNVGSDENMTPYLYVPEVFPLNQID 239 Query: 72 EIVVTHWHRDHSGGIGDICKSINNDTTYCIKKLPRNPQREEIIGNGEQQYVYLKDGDVIK 131 ++VTH H DH G + + K YC + L DV Sbjct: 240 AVIVTHAHLDHQGLVPLLFKYGYEGPVYCT-----------PPTRDLMVLLQLDYIDVAA 288 Query: 132 TEGATL 137 EG + Sbjct: 289 KEGKKI 294 >2YCB-A nrPDB Length = 636 Score = 50.6 bits (119), Expect = 8e-07, Method: Composition-based stats. Identities = 32/199 (16%), Positives = 59/199 (29%), Gaps = 30/199 (15%) Query: 30 GTNTYLVGTGPRRILIDTGEP---AIPEYISCLKQALTEFNTAIQEIVVTHWHRDHSGGI 86 G + + T R+L+D G + ++ +++TH H DHSG + Sbjct: 192 GRSCLYLQTPNSRVLLDCGVNVAGGDDKNSYPYLNVPEFTLDSLDAVIITHAHLDHSGFL 251 Query: 87 GDICKSINNDTTYCIKKLPRNPQR------------EEIIG-------NGEQQYVYLKDG 127 + + YC +E + + + L G Sbjct: 252 PYLYHYGYDGPVYCTAPTRDLMTLLQLDHIDIAHREDEPLPFNVKHVKKSVKHTITLDYG 311 Query: 128 DVIKTEGATLRVLYTPGHTDDHMALLLE----EENAIFSGDCILGEGTTVFEDLYDYMNS 183 +V L+ GH L + N +++GD + L N Sbjct: 312 EVTDIAPDIRLTLHNAGHILGSAMAHLHIGDGQHNMVYTGDFKYEQSRL----LEAAANR 367 Query: 184 LKELLKIKADIIYPGHGPV 202 + + + Y GH V Sbjct: 368 FPRIETLVMESTYGGHEDV 386 >3ZQ4-A nrPDB Length = 555 Score = 48.6 bits (114), Expect = 3e-06, Method: Composition-based stats. Identities = 29/144 (20%), Positives = 54/144 (37%), Gaps = 9/144 (6%) Query: 30 GTNTYLVGTGPRRILIDTGEPAIPEYISCLKQALTEFN------TAIQEIVVTHWHRDHS 83 G NTY V +LID G + + + + ++ I+ + +TH H DH Sbjct: 21 GKNTYAVQFQDEIVLIDAGIKFPEDELLGIDYVIPDYTYLVKNEDKIKGLFITHGHEDHI 80 Query: 84 GGIGDICKSINNDTTYCIKKLPRNPQREEIIGNGEQQYVY-LKDGDVIKTEGATLRVLYT 142 GGI + + +N + + E G Q + + + D++K + T Sbjct: 81 GGIPYLLRQVNIPVYGGKLAIGLLRNKLEEHGLLRQTKLNIIGEDDIVKFRKTAVSFFRT 140 Query: 143 PGHTDDH--MALLLEEENAIFSGD 164 D + + N + +GD Sbjct: 141 THSIPDSYGIVVKTPPGNIVHTGD 164 >4XWT-A nrPDB Length = 559 Score = 46.3 bits (108), Expect = 2e-05, Method: Composition-based stats. Identities = 30/146 (20%), Positives = 54/146 (36%), Gaps = 12/146 (8%) Query: 30 GTNTYLVGTGPRRILIDTGEPAIPE------YISCLKQALTEFNTAIQEIVVTHWHRDHS 83 G N + G +++D G I L E I+ ++TH H DH Sbjct: 31 GKNITVFRYGDEIVVVDGGLAFPKAHQMGIDLIVPRIDYLLEHQDKIKGWILTHGHEDHI 90 Query: 84 GGIGDICKSINNDTTYCIKKLPRNPQREEIIGNGEQQY--VYLKDGDVIKTEGATLRVLY 141 GG+ I + Y + L RE++ G Q + GD ++ + + + Sbjct: 91 GGLPYIFARLPRVPVYGLP-LTLALVREKLSEFGLQDVDLREVTYGDEVRFGQSFVAEFF 149 Query: 142 TPGHT-DDHMALLL--EEENAIFSGD 164 H+ D+ +L + + +GD Sbjct: 150 CMTHSIPDNAGYILKTPVGDVLHTGD 175 >5A0V-A nrPDB Length = 561 Score = 44.8 bits (104), Expect = 5e-05, Method: Composition-based stats. Identities = 32/203 (15%), Positives = 69/203 (33%), Gaps = 9/203 (4%) Query: 26 MTLQGTNTYLVGTGPRRILIDTGEPAIPEYISCLKQALTEFNTAIQEIVVTHWHRDHSGG 85 MT+ L+ + + +P I I ++ + I+ IV+TH H DH GG Sbjct: 34 MTVFEYGGRLLIVDCGVLFPEEEQPGID-LILPDFTSIRDRLDDIEGIVLTHGHEDHIGG 92 Query: 86 IGDICKSINNDTTYCIKKLPRNPQREEIIGNGEQQYVYLKDGDVIKTEGATLRVLYTPGH 145 + + + + K + + + + +G + + Sbjct: 93 VPFLLREKPDIPLIGSKLTLALIEAKLQEHRIRPYTLEVAEGHRERVGPFDCEFVAVNHS 152 Query: 146 TDDHMALLL--EEENAIFSGDCILGEGTTV--FEDLYDYMNSLKE----LLKIKADIIYP 197 D +A+ + + +GD + + DL+ + +E LL + P Sbjct: 153 IPDALAVAIRTPAGMVVHTGDFKMDQLPLDGRLTDLHAFARLSEEGIDLLLADSTNAEVP 212 Query: 198 GHGPVIHNAEAKIQQYISHRNIR 220 G P + ++Q ++ R Sbjct: 213 GFVPPERDISNVLRQVFANARKR 235 >3AF5-A nrPDB Length = 651 Score = 44.4 bits (103), Expect = 6e-05, Method: Composition-based stats. Identities = 42/243 (17%), Positives = 75/243 (30%), Gaps = 40/243 (16%) Query: 5 LQRVERLSNRVVRVLGCNPGPMTLQGTNTYLVGTGPRRILIDTG---------EPAIPEY 55 + R +R +R+ G G G + LV T +L+D G A P + Sbjct: 178 IYRKPEYKSRWIRITGL--GGFREVGRSALLVQTDESFVLVDFGVNVAMLNDPYKAFPHF 235 Query: 56 ISCLKQALTEFNTAIQEIVVTHWHRDHSGGIGDICK-SINNDTTYCIK------KLPRNP 108 + Q + + I++TH H DH G + + + ++ + Y L + Sbjct: 236 DAPEFQYVLREGL-LDAIIITHAHLDHCGMLPYLFRYNLFDGPIYTTPPTRDLMVLLQKD 294 Query: 109 QREEIIGNGEQQY-------------VYLKDGDVIKTEGATLRVLYTPGHTDDHMALLLE 155 E NG+ + L G+V L+ GH + L Sbjct: 295 FIEIQQSNGQDPLYRPRDIKEVIKHTITLDYGEVRDISPDIRLTLHNAGHILGSAIVHLH 354 Query: 156 E----ENAIFSGDCILGEGTTVFEDLYDYMNSLKELLKIKADIIYPGHGPVIHNAEAKIQ 211 N +GD + + L + + Y G + E + Sbjct: 355 IGNGLHNIAITGDFKFIPTRLLEPANAKFP----RLETLVMESTYGGANDIQMPREEAEK 410 Query: 212 QYI 214 + I Sbjct: 411 RLI 413 >3T3N-A nrPDB Length = 562 Score = 39.8 bits (91), Expect = 0.001, Method: Composition-based stats. Identities = 27/145 (18%), Positives = 45/145 (31%), Gaps = 11/145 (7%) Query: 39 GPRRILIDTGEPAIPEYISCLKQALTEFNTAIQEIVVTHWHRDHSGGIGDICKSINND-- 96 + G P + I + L E I+ V+TH DH GG+ + I Sbjct: 46 DGGLAFPEEGMPGVDLLIPRV-DYLIEHRHKIKAWVLTHGAEDHIGGLPFLLPMIFGKES 104 Query: 97 --TTYCIK---KLPRNPQREEIIGNGEQQYVYLKDGDVIKTEGA-TLRVLYTPGHTDDHM 150 Y + L R E + G + D I+ TL + D+ Sbjct: 105 PVPIYGARLTLGLLRGKLEEFGLRPGAFNLKEISPDDRIQVGRYFTLDLFRMTHSIPDNS 164 Query: 151 ALLL--EEENAIFSGDCILGEGTTV 173 +++ + +GD L Sbjct: 165 GVVIRTPIGTIVHTGDFKLDPTPID 189 >3AJ3-A nrPDB Length = 274 Score = 39.4 bits (90), Expect = 0.002, Method: Composition-based stats. Identities = 49/222 (22%), Positives = 77/222 (34%), Gaps = 59/222 (26%) Query: 24 GPMTLQGTNTYLVGTGPRRILIDTGE------------PAIPEYISCLKQALTEFN---T 68 G + + L+ R LIDTG I E + AL Sbjct: 29 GEVRFP-VYSILIEHAEGRFLIDTGYDYDHVMKVLPFEKPIQEKHQTIPGALGLLGLEPR 87 Query: 69 AIQEIVVTHWHRDHSGGIGDICKSINNDTTYC-IKKLPR--NPQREEIIGNGEQQYVYLK 125 I +V +H+H DH GG K + C ++P+ NPQ E +G + + Sbjct: 88 DIDVVVNSHFHFDHCGG----NKYFPHAKKICHRSEVPQACNPQPFEHLGYSDLSFSAEA 143 Query: 126 ------------------------DGDVIKTEGATLRVLYTPGHTDDHMALLLE------ 155 DGDV G L + TPGH+ H +LL+E Sbjct: 144 AEARGATAQLLEGTTRANSTFEGIDGDVDLARGVKL--ISTPGHSIGHYSLLVEFPRRKP 201 Query: 156 ---EENAIFSGDCILGEGTTVF-EDLYDYMNSLKELLKIKAD 193 +A ++ + F D +NS++++ K+ D Sbjct: 202 ILFTIDAAYTQKSLETLCQAAFHIDPVAGVNSMRKVKKLAED 243 >5HAA-A nrPDB Length = 470 Score = 37.5 bits (85), Expect = 0.007, Method: Composition-based stats. Identities = 23/114 (20%), Positives = 37/114 (32%), Gaps = 15/114 (13%) Query: 63 LTEFNTAIQEIVVTHWHRDHSGGIGDICKSINN---DTTYCIKKLPRNPQREEIIGNGEQ 119 + E N ++ IV TH H DH G I + T Y + E G Sbjct: 90 MNEVNGNVRAIVCTHGHLDHIGAIPKLAHRYAAPIIATPYTTALIKHQIDSERKFGVKNN 149 Query: 120 QYVYLKDG-----------DVIKTEGATLRVLYTPGHTDDHMALLLEEENAIFS 162 V LK G + I T+ + + ++ HT + + + Sbjct: 150 -IVALKAGETLEITKDITIEFINTQHSIIDTVFVAIHTPSGAVVYACDFKFDRT 202 >4PDX-A nrPDB Length = 640 Score = 37.1 bits (84), Expect = 0.008, Method: Composition-based stats. Identities = 36/239 (15%), Positives = 64/239 (26%), Gaps = 54/239 (22%) Query: 31 TNTYLVGTGPRRILIDTGEPAIPEYISCLKQALTEFNTAIQEIVVTHWHRDHSGGIG--- 87 +N V I+ID + I ++ TH H DH GG+ Sbjct: 105 SNITFVEGEKGIIVIDPLVTPPAAKAALDLYFQHRPQKPIVAVIYTHSHTDHYGGVKGII 164 Query: 88 ---------------------DICKSINNDTTYCIKKLPRNP-----QREEIIGNGEQQY 121 I +++ + L + +GNG Sbjct: 165 SEADVKSGKVQVIAPAGFMDEAISENVLAGNIMSRRALYSYGLLLPHNAQGNVGNGLGVT 224 Query: 122 VY-------------LKDGDVIKTEGATLRVLYTPG-HTDDHMALLLE-------EENAI 160 + ++ G+ + +G L TPG M + ENA Sbjct: 225 LATGDPSIIAPTKTIVRTGEKMIIDGLEFDFLMTPGSEAPAEMHFYIPALKALCTAENAT 284 Query: 161 FSGDCILGEGTTVFEDLYDYMNSLKELLKIKAD---IIYPGHGPVIHNAEAKIQQYISH 216 + D + L E L + + +++ H + + I YI Sbjct: 285 HTLHNFYTLRGAKTRDTSKWTEYLNETLDMWGNDAEVLFMPHTWPVWGNK-HINDYIGK 342 >4AXH-A nrPDB Length = 668 Score = 36.3 bits (82), Expect = 0.017, Method: Composition-based stats. Identities = 18/72 (25%), Positives = 28/72 (38%), Gaps = 7/72 (9%) Query: 14 RVVRVLGCNPGPMTLQGTNTYLVGTGPRRILIDTGEPAIPEYISCLKQALTEFNTAIQEI 73 ++ +V G +P MT ++ +LIDT A + I + Sbjct: 123 KLYQVRGLDPANMT-------IIEGDSGLVLIDTLTTAETARAALDLYFQHRPKKPIVAV 175 Query: 74 VVTHWHRDHSGG 85 V +H H DH GG Sbjct: 176 VYSHSHIDHFGG 187 >4NUR-A nrPDB Length = 633 Score = 34.8 bits (78), Expect = 0.045, Method: Composition-based stats. Identities = 31/242 (12%), Positives = 64/242 (26%), Gaps = 53/242 (21%) Query: 31 TNTYLVGTGPRRILIDTGEPAIPEYISCLKQALTEFNTAIQEIVVTHWHRDHSGGIGDIC 90 +N +V + D + + ++ TH H DH GG+ + Sbjct: 105 SNMTIVEGKDGITIFDPLISQETAKAALDLYYKHRPKKPVVAVIYTHSHVDHYGGVRGVV 164 Query: 91 KSINND----TTYCIKKLPRNPQREEIIGNGEQQ-------------------------- 120 + Y + E ++ Sbjct: 165 DEADVKAGKVKIYAPLGFLEHAVAENVMAGTAMSRRASYMYGNLLPPDAKGQLGAGLGTT 224 Query: 121 ------------YVYLKDGDVIKTEGATLRVLYTPG-HTDDHMALLLEEENAIFSGD--- 164 + + G+ +G T +Y PG M ++E+ A+ + + Sbjct: 225 TSAGTVTLIPPTDIIKETGETHVIDGLTYEFMYAPGSEAPAEMLYYIKEKKALNAAEDST 284 Query: 165 ----CILGEGTTVFEDLYDYMNSLKELLKIKAD---IIYPGHGPVIHNAEAKIQQYISHR 217 D + L E LK+ D ++Y H + + +Q R Sbjct: 285 HTLHNTYSLRGAKIRDPLAWSKYLNEALKLWGDDVQVMYAMHHWPVWGNKEVREQLSLQR 344 Query: 218 NI 219 ++ Sbjct: 345 DM 346 >4B09-A nrPDB Length = 240 Score = 33.6 bits (75), Expect = 0.11, Method: Composition-based stats. Identities = 27/169 (15%), Positives = 50/169 (29%), Gaps = 27/169 (15%) Query: 34 YLVGTGPRRILIDTGEPAIPEYISCLKQALTEFNTAIQEIVVTHW-HRDH-----SGGIG 87 Y+ T P IL+D P + C + + F+ +V D G Sbjct: 49 YVRQTPPDLILLDLMLPGTDGLMLCRE--IRRFSDIPIVMVTAKIEEIDRLLGLEIGADD 106 Query: 88 DICKSINNDTTYCI----------KKLPRNPQREEIIGNGEQQYVYLKDGDVIKTEGATL 137 ICK + ++ + E + E ++ G ++ A Sbjct: 107 YICKPYSPREVVARVKTILRRCKPQRELQQQDAESPLIIDEGRFQASWRGKMLDLTPAEF 166 Query: 138 RVLYTPGHTDDHMAL-------LLEEENAI--FSGDCILGEGTTVFEDL 177 R+L T H + L ++ + + D + E L Sbjct: 167 RLLKTLSHEPGKVFSREQLLNHLYDDYRVVTDRTIDSHIKNLRRKLESL 215 >3ZWF-A nrPDB Length = 368 Score = 33.2 bits (74), Expect = 0.13, Method: Composition-based stats. Identities = 18/81 (22%), Positives = 33/81 (40%), Gaps = 5/81 (6%) Query: 25 PMTLQGTNTYLVGTGPRRILIDTGEPAIPEYISCLKQALTEFNTAIQEIVVTHWHRDHSG 84 P +G + ++ L D GE + + +A I +I +TH H DH Sbjct: 13 PSPTRGASAVVLRCEGECWLFDCGEGTQTQLMKSQLKA-----GRITKIFITHLHGDHFF 67 Query: 85 GIGDICKSINNDTTYCIKKLP 105 G+ + +I+ + + K P Sbjct: 68 GLPGLLCTISLQSGSMVSKQP 88 >2CG3-A nrPDB Length = 658 Score = 32.8 bits (73), Expect = 0.16, Method: Composition-based stats. Identities = 24/180 (13%), Positives = 53/180 (29%), Gaps = 43/180 (23%) Query: 32 NTYLVGTGPRRILIDTGEPAIPEYISCLKQALTEFNTAIQEIVVTHWHRDHSGGIGDICK 91 N + I++DT + + I+ ++ +H H DH GG+ + + Sbjct: 124 NITFIRGDSGWIVVDTLTTPATARAAYELVSRELGERPIRTVIYSHAHADHFGGVRGLVE 183 Query: 92 --------------------SINNDTTYCIKKLPRNP---QREEIIGNGEQQYVYL---- 124 +I + + R + G Q + + Sbjct: 184 PQQVASGAVQIIAPAGFMEAAIKENVLAGNAMMRRATYQYGTQLPKGPQGQVDMAIGKGL 243 Query: 125 ---------------KDGDVIKTEGATLRVLYTPG-HTDDHMALLLEEENAIFSGDCILG 168 +G+ + +G TPG + M + L + A+ + ++G Sbjct: 244 ARGPLSLLAPTRLIEGEGEDLVLDGVPFTFQNTPGTESPAEMNIWLPRQKALLMAENVVG 303 >4GBM-A nrPDB Length = 323 Score = 31.7 bits (70), Expect = 0.38, Method: Composition-based stats. Identities = 13/68 (19%), Positives = 30/68 (44%), Gaps = 2/68 (2%) Query: 194 IIYPGHGPVIHNAEAKIQQYISHRNIREQQILTLFRENFEKSFTVMELVKIIYKNTPENL 253 ++ GH + E + + + + +EQ L+ E +K+F ME+ + + + Sbjct: 50 VMLAGHSSLFSPPELHLLPFNTMKERQEQLNLSYLGEGLQKTF--MEVKNLDATASQALI 107 Query: 254 HEMAKHNL 261 ++ NL Sbjct: 108 KDLESQNL 115 >3BDD-A nrPDB Length = 142 Score = 31.7 bits (70), Expect = 0.43, Method: Composition-based stats. Identities = 20/82 (24%), Positives = 37/82 (45%), Gaps = 10/82 (12%) Query: 210 IQQYISHRNIREQQILTLFRENFEKSFTVMELVKIIYKNTPENLHEMAKHNLLL------ 263 ++ + + ++ I LF + S T +++ + K+ P LH++A L Sbjct: 5 MEDLLYRLKVADETISNLFEKQLGISLTRYSILQTLLKDAP--LHQLALQERLQIDRAAV 62 Query: 264 --HLKKLEKEGKIFSNTDPDKK 283 HLK LE+ G I +PD + Sbjct: 63 TRHLKLLEESGYIIRKRNPDNQ 84 >2N7L-C nrPDB Length = 141 Score = 31.3 bits (69), Expect = 0.54, Method: Composition-based stats. Identities = 12/59 (20%), Positives = 22/59 (37%) Query: 14 RVVRVLGCNPGPMTLQGTNTYLVGTGPRRILIDTGEPAIPEYISCLKQALTEFNTAIQE 72 +V+R+LG NP P LQ + G + D + + + L ++ Sbjct: 58 KVMRMLGQNPTPEELQEMIDEVDEDGSGTVDFDEFLVMMVRXMKDDSENLYFQGRRVRI 116 >4V7O-A5 nrPDB Length = 799 Score = 29.8 bits (65), Expect = 1.6, Method: Composition-based stats. Identities = 25/131 (19%), Positives = 51/131 (38%), Gaps = 18/131 (13%) Query: 19 LGCNPGPMTLQGTNTYLVGTGPRRILIDTGEPAIPEYIS---CLKQALTEFNTAIQEIVV 75 + C + L +N YL+ +ILID + ++I+ + +L +F I+ IV+ Sbjct: 360 ISCFAYLLELDPSNAYLIYD---KILIDLYDTLADQFINSRHRIISSLKQFTRVIRFIVM 416 Query: 76 THWHRDHSG-GIGDICKSINNDTTYCIKKLPRNPQREEIIGNGEQQYVYLKD----GDVI 130 +R H + + ++ + T L ++ ++D D I Sbjct: 417 DKLYRVHITNVLSMLVSKLDMNDTNLTSNLINGIVS-------IAAFIPIQDLTGEDDYI 469 Query: 131 KTEGATLRVLY 141 E TL ++ Sbjct: 470 SFESDTLPLVQ 480 >4GCW-A nrPDB Length = 320 Score = 29.4 bits (64), Expect = 1.9, Method: Composition-based stats. Identities = 14/58 (24%), Positives = 23/58 (39%), Gaps = 5/58 (8%) Query: 35 LVGTGPRRILIDTGEPAIPEYISCLKQALTEFNTAIQEIVVTHWHRDHSGGIGDICKS 92 L+ L D GE + + + I++I +TH H DH G+ + S Sbjct: 26 LLEERRSVWLFDCGEATQHQMLHTTIKP-----RKIEKIFITHMHGDHVYGLPGLLGS 78 >2WJ4-A nrPDB Length = 276 Score = 29.4 bits (64), Expect = 1.9, Method: Composition-based stats. Identities = 28/154 (18%), Positives = 48/154 (31%), Gaps = 8/154 (5%) Query: 27 TLQGTNTYLVGTGPRRILIDTGEP--AIPEYISCLKQALTEFNTAIQEIVVTHWHRDHSG 84 L +V L + P E + + L + + V+H H G Sbjct: 49 ELDADFRVIVPNWRGHGLSPSEVPDFGYQEQVKDALEILDQLGVE-TFLPVSHSH----G 103 Query: 85 GIGDICKSINNDTTYCIKKLPRNPQREEIIGNGEQQYVYLKDGDVIKTEGATLRVLYTPG 144 G + + + + + + LKD + + L ++ G Sbjct: 104 GWVLVELLEQAGPERAPRGIIMDWLMWAPKPDFAKSLTLLKDPERWREGTHGLFDVWLDG 163 Query: 145 HTDDHMALLLEEENAIFSGDCILGEGTTVFEDLY 178 H + + L EE A + DC G V ED Y Sbjct: 164 HDEKRVRHHLLEEMADYGYDCWGRSGR-VIEDAY 196 >5MTZ-A nrPDB Length = 874 Score = 29.4 bits (64), Expect = 2.0, Method: Composition-based stats. Identities = 15/55 (27%), Positives = 24/55 (43%), Gaps = 1/55 (1%) Query: 37 GTGPRRILIDTGEPAIPEYISCLKQ-ALTEFNTAIQEIVVTHWHRDHSGGIGDIC 90 T R I++D GE + Q A+ ++ I ++H H DH GI + Sbjct: 535 NTINRNIMLDAGENTLGTIHRMFSQLAVKSIFQDLKMIYLSHLHADHHLGIISVL 589 >3RHD-A nrPDB Length = 486 Score = 29.0 bits (63), Expect = 2.4, Method: Composition-based stats. Identities = 15/52 (28%), Positives = 27/52 (51%), Gaps = 4/52 (7%) Query: 222 QQILTLFRENFEKSFTVMELVKIIYKNTPENLHEMAKHNLLLHLKKLEKEGK 273 ++I L RE +++ E K + KN P ++N+L+++ K KE K Sbjct: 26 KKIPALSREEAKEAIDTAEKYKEVMKNLPIT----KRYNILMNIAKQIKEKK 73 >2I3C-A nrPDB Length = 315 Score = 29.0 bits (63), Expect = 2.8, Method: Composition-based stats. Identities = 11/48 (22%), Positives = 18/48 (37%) Query: 143 PGHTDDHMALLLEEENAIFSGDCILGEGTTVFEDLYDYMNSLKELLKI 190 P H D M L L+ + GDC + Y+ + + K+ Sbjct: 256 PLHPGDPMFLTLDGKTIPLGGDCTVYPVFVNEAAYYEKKEAFAKTTKL 303 >2R2D-A nrPDB Length = 276 Score = 28.6 bits (62), Expect = 3.5, Method: Composition-based stats. Identities = 24/125 (19%), Positives = 43/125 (34%), Gaps = 31/125 (24%) Query: 31 TNTYLVGTGPRRILIDTG-----------EPAIPEYISCLK--------QALTEFN---T 68 + YL+ +L DTG PA + + + L + Sbjct: 43 VSAYLIQCTDATVLYDTGCHPECMGTNGRWPAQSQLNAPYIGASECNLPERLRQLGLSPD 102 Query: 69 AIQEIVVTHWHRDHSGGIGDICKS--INNDTTYCIKKLPRNPQREEIIGNGEQQYVYLKD 126 I +V++H H DH+G + KS I ++ + R G+ Y+ +KD Sbjct: 103 DISTVVLSHLHNDHAGCVEYFGKSRLIAHEDEFATAV------RYFATGDHSSPYI-VKD 155 Query: 127 GDVIK 131 + Sbjct: 156 IEAWL 160 >4XHZ-A nrPDB Length = 338 Score = 28.2 bits (61), Expect = 3.8, Method: Composition-based stats. Identities = 31/199 (15%), Positives = 67/199 (33%), Gaps = 18/199 (9%) Query: 89 ICKSINNDTTYCIKKLPRNPQREEIIGNGEQQYVYLKDGDVIKTEGATLRVL--YTPGHT 146 I K +N+ K++ + + + VY +D D + +R Sbjct: 101 IVKDMNDYPPVFSKRIYKGMVAPDAVKGTPITTVYAEDADPPGLPASRVRYRVDDVQFPY 160 Query: 147 DDHMALLLEEENAIFSGDCILGEGTTVF----------EDLYDYMNSLKELLKIKADIIY 196 + + E+ + + + E TT+F E + ++K L+ +I Sbjct: 161 PASIFEVEEDSGRVITRVNLNEEPTTIFKLVVVAFDDGEPVMSSSATVKILVLHPGEIPR 220 Query: 197 PGHGPVIHNAEAKIQQ------YISHRNIREQQILTLFRENFEKSFTVMELVKIIYKNTP 250 +++ IS I + + ++ N E +F + + +IY N P Sbjct: 221 FTQEEYRPPPVSELATKGTMVGVISAAAINQSIVYSIVSGNEEDTFGINNITGVIYVNGP 280 Query: 251 ENLHEMAKHNLLLHLKKLE 269 + + L + LE Sbjct: 281 LDYETRTSYVLRVQADSLE 299 >1YQ9-A nrPDB Length = 264 Score = 27.4 bits (59), Expect = 7.1, Method: Composition-based stats. Identities = 10/30 (33%), Positives = 16/30 (53%) Query: 10 RLSNRVVRVLGCNPGPMTLQGTNTYLVGTG 39 +L + + + GC P PM GT +L+ G Sbjct: 137 KLGVKAINIAGCPPNPMNFVGTVVHLLTKG 166 >5TEK-A nrPDB Length = 250 Score = 27.1 bits (58), Expect = 8.9, Method: Composition-based stats. Identities = 16/84 (19%), Positives = 26/84 (30%), Gaps = 4/84 (4%) Query: 28 LQGTNTYLVGTGPRRILIDTGEPAIPEYISCLKQALTEFNTAIQEIVVTHWHR-DHSGGI 86 Q ++LV +LI + F + + I + H H+ D G Sbjct: 89 FQQVESWLVAKPNTSVLIAPNFAIGAVLSMHFAKQAARFFDSAEVIELHHPHKADAPSGT 148 Query: 87 GDICKSINNDTTYCIKKLPRNPQR 110 + + K LP NP Sbjct: 149 AARTAKLIAE---ARKGLPPNPDA 169 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.312 0.124 0.310 Lambda K H 0.267 0.0387 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 10,245,892 Number of Sequences: 36641 Number of extensions: 390483 Number of successful extensions: 1456 Number of sequences better than 10.0: 74 Number of HSP's better than 10.0 without gapping: 66 Number of HSP's successfully gapped in prelim test: 54 Number of HSP's that attempted gapping in prelim test: 1312 Number of HSP's gapped (non-prelim): 126 length of query: 288 length of database: 10,336,785 effective HSP length: 96 effective length of query: 192 effective length of database: 6,819,249 effective search space: 1309295808 effective search space used: 1309295808 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.5 bits) S2: 58 (27.0 bits)