BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q53FA7 (332 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 2OBY-A nrPDB 675 0.0 1WLY-A nrPDB 139 1e-33 4A27-A nrPDB 133 1e-31 5K1S-A nrPDB 120 1e-27 4RVS-A nrPDB 118 4e-27 1QOR-A nrPDB 118 5e-27 3QWB-A nrPDB 113 9e-26 1YB5-A nrPDB 112 3e-25 2WEK-A nrPDB 110 7e-25 3TQH-A nrPDB 107 1e-23 4J6F-A nrPDB 105 3e-23 3UOG-A nrPDB 100 6e-22 3JYN-A nrPDB 96 2e-20 3SLK-A nrPDB 94 1e-19 4EYE-A nrPDB 85 4e-17 4IDE-A nrPDB 80 1e-15 3PII-A nrPDB 80 1e-15 5A3V-A nrPDB 77 7e-15 3FBG-A nrPDB 74 1e-13 5ENV-A nrPDB 74 1e-13 1LLU-A nrPDB 73 2e-13 3B70-A nrPDB 72 2e-13 4DVJ-A nrPDB 71 7e-13 3MEQ-A nrPDB 68 6e-12 2VN8-A nrPDB 67 1e-11 4Z6K-A nrPDB 64 7e-11 4A10-A nrPDB 64 7e-11 2DFV-A nrPDB 64 1e-10 1H2B-A nrPDB 62 3e-10 3S2F-A nrPDB 61 6e-10 2EER-A nrPDB 61 7e-10 4EJ6-A nrPDB 60 1e-09 4Y1B-A nrPDB 59 3e-09 2J3K-A nrPDB 58 5e-09 5YAT-A nrPDB 58 6e-09 2VCY-A nrPDB 57 1e-08 3HZZ-A nrPDB 56 2e-08 3GFB-A nrPDB 56 3e-08 6FG0-A nrPDB 55 5e-08 1V3V-A nrPDB 53 1e-07 6N7L-A nrPDB 53 2e-07 5VM2-A nrPDB 52 3e-07 2Y05-A nrPDB 52 4e-07 4EEZ-A nrPDB 50 9e-07 1R37-A nrPDB 50 2e-06 3FPC-A nrPDB 49 4e-06 4GKV-A nrPDB 48 5e-06 3FSR-A nrPDB 47 1e-05 3IP1-A nrPDB 47 2e-05 2DQ4-A nrPDB 45 4e-05 1MC5-A nrPDB 45 5e-05 1KEV-A nrPDB 43 2e-04 5LB9-A nrPDB 41 6e-04 2OUI-A nrPDB 40 0.001 2H6E-A nrPDB 40 0.001 3COS-A nrPDB 38 0.006 1YKF-A nrPDB 37 0.016 2VNA-A nrPDB 36 0.024 4ILK-A nrPDB 35 0.034 1HSO-A nrPDB 34 0.076 1F8F-A nrPDB 34 0.082 1HSZ-A nrPDB 34 0.089 4OH1-A nrPDB 33 0.16 1PL8-A nrPDB 33 0.19 1U3W-A nrPDB 33 0.23 2CF5-A nrPDB 32 0.26 3FPL-A nrPDB 32 0.28 3WLE-A nrPDB 32 0.30 1P0F-A nrPDB 32 0.38 5TNX-A nrPDB 32 0.43 5GXF-A nrPDB 32 0.49 1CDO-A nrPDB 31 0.91 1O89-A nrPDB 31 0.92 1Q1N-A nrPDB 31 0.96 3QE3-A nrPDB 30 1.1 1EE2-A nrPDB 30 1.5 4JLW-A nrPDB 29 3.2 1LTX-R nrPDB 28 5.3 4OAQ-A nrPDB 28 5.5 >2OBY-A nrPDB Length = 338 Score = 675 bits (1741), Expect = 0.0, Method: Compositional matrix adjust. Identities = 332/332 (100%), Positives = 332/332 (100%) Query: 1 MLAVHFDKPGGPENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNI 60 MLAVHFDKPGGPENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNI Sbjct: 7 MLAVHFDKPGGPENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNI 66 Query: 61 LGLEASGHVAELGPGCQGHWKIGDTAMALLPGGGQAQYVTVPEGLLMPIPEGLTLTQAAA 120 LGLEASGHVAELGPGCQGHWKIGDTAMALLPGGGQAQYVTVPEGLLMPIPEGLTLTQAAA Sbjct: 67 LGLEASGHVAELGPGCQGHWKIGDTAMALLPGGGQAQYVTVPEGLLMPIPEGLTLTQAAA 126 Query: 121 IPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQM 180 IPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQM Sbjct: 127 IPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQM 186 Query: 181 AEKLGAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIGGSYWEKNVNCLALDGRWVLYGL 240 AEKLGAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIGGSYWEKNVNCLALDGRWVLYGL Sbjct: 187 AEKLGAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIGGSYWEKNVNCLALDGRWVLYGL 246 Query: 241 MGGGDINGPLFSKLLFKRGSLITSLLRSRDNKYKQMLVNAFTEQILPHFSTEGPQRLLPV 300 MGGGDINGPLFSKLLFKRGSLITSLLRSRDNKYKQMLVNAFTEQILPHFSTEGPQRLLPV Sbjct: 247 MGGGDINGPLFSKLLFKRGSLITSLLRSRDNKYKQMLVNAFTEQILPHFSTEGPQRLLPV 306 Query: 301 LDRIYPVTEIQEAHKYMEANKNIGKIVLELPQ 332 LDRIYPVTEIQEAHKYMEANKNIGKIVLELPQ Sbjct: 307 LDRIYPVTEIQEAHKYMEANKNIGKIVLELPQ 338 >1WLY-A nrPDB Length = 333 Score = 139 bits (351), Expect = 1e-33, Method: Compositional matrix adjust. Identities = 113/349 (32%), Positives = 165/349 (47%), Gaps = 35/349 (10%) Query: 1 MLAVHFDKPGGPENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDP-----PP 55 ++A K GGP+N +EV SPG G+V L+ A +N D R G P PP Sbjct: 2 VMAAVIHKKGGPDNFVWEEVKVGSPGPGQVRLRNTAIGVNFLDTYHRAGIPHPLVVGEPP 61 Query: 56 GASNILGLEASGHVAELGPGCQGHWKIGDTAMALLPG-GGQAQYVTVPEGLLMPIPEGLT 114 ++G EA+ V E+GPG + +G+ LP G +Q P L+ +P+ L Sbjct: 62 ---IVVGFEAAAVVEEVGPGVTD-FTVGERVCTCLPPLGAYSQERLYPAEKLIKVPKDLD 117 Query: 115 LTQA--AAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTA 172 L A + +TA LLH V+ GDYVLIHA G+G + R GA + T Sbjct: 118 LDDVHLAGLMLKGMTAQYLLHQTHKVKPGDYVLIHAAAGGMGHIMVPWARHLGATVIGTV 177 Query: 173 GSQKKLQMAEKLGAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIGGSYWEKNVNCLALD 232 +++K + A KLG NY +DF+E + T G GV+++ D IG +K+++CL Sbjct: 178 STEEKAETARKLGCHHTINYSTQDFAEVVREITGGKGVDVVYDSIGKDTLQKSLDCLRPR 237 Query: 233 GRWVLYGLMGGGDINGPL-FSKLLFKRGSLITSLL--------RSRDNKYKQMLVNAFTE 283 G YG G + P+ + L RGSL + RS ++ + L +A Sbjct: 238 GMCAAYGHASG--VADPIRVVEDLGVRGSLFITRPALWHYMSNRSEIDEGSKCLFDAVKA 295 Query: 284 QILPHFSTEGPQRLLPVLDRIYPVTEIQEAHKYMEANKNIGKIVLELPQ 332 +L H S + + +P+ E AHKYM + IG IVL LPQ Sbjct: 296 GVL-HSS----------VAKTFPLREAAAAHKYMGGRQTIGSIVL-LPQ 332 >4A27-A nrPDB Length = 349 Score = 133 bits (335), Expect = 1e-31, Method: Compositional matrix adjust. Identities = 99/348 (28%), Positives = 169/348 (48%), Gaps = 23/348 (6%) Query: 1 MLAVHFDKPGGPENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNI 60 M AV GG L + A P P +GE+ ++V A LN DLM RQG D PP + Sbjct: 4 MRAVVLAGFGGLNKLRLFRKAMPEPQDGELKIRVKACGLNFIDLMVRQGNIDNPPKTPLV 63 Query: 61 LGLEASGHVAELGPGCQGHWKIGDTAMALLPGGGQAQYVTVPEGLLMPIPEGLTLTQAAA 120 G E SG V LG +G ++IGD MA + A+ V P + IP+ ++ ++AAA Sbjct: 64 PGFECSGIVEALGDSVKG-YEIGDRVMAFVNYNAWAEVVCTPVEFVYKIPDDMSFSEAAA 122 Query: 121 IPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQM 180 P ++TA+ +L V N++ G VL+H+ GVG A QL +P VT Sbjct: 123 FPMNFVTAYVMLFEVANLREGMSVLVHSAGGGVGQAVAQL---CSTVPNVTVFGTASTFK 179 Query: 181 AEKLGAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIGGSYWEKNVNCLALDGRWVLYG- 239 E + + + + +K GV+++LDC+ G K ++ L G ++LYG Sbjct: 180 HEAIKDSVTHLFDRNADYVQEVKRISAEGVDIVLDCLCGDNTGKGLSLLKPLGTYILYGS 239 Query: 240 --LMGGGDINGPLFSKL-----------LFKRGSLIT--SLLRSRDNKYKQMLVNAFTEQ 284 ++ G + F+K L++ +I SLL + + L+ E+ Sbjct: 240 SNMVTGETKSFFSFAKSWWQVEKVNPIKLYEENKVIAGFSLLNLLFKQGRAGLIRGVVEK 299 Query: 285 ILPHFSTEGPQRLLPVLDRIYPVTEIQEAHKYMEANKNIGKIVLELPQ 332 ++ ++ +++ PV+D ++ + E++EA + + NIGK++L++ + Sbjct: 300 LIGLYNQ---KKIKPVVDSLWALEEVKEAMQRIHDRGNIGKLILDVEK 344 >5K1S-A nrPDB Length = 362 Score = 120 bits (300), Expect = 1e-27, Method: Compositional matrix adjust. Identities = 107/364 (29%), Positives = 167/364 (45%), Gaps = 52/364 (14%) Query: 1 MLAVHFDKPGGPENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNI 60 M AV G NL ++ + P PG GEVLL+V A + D++ R+G P I Sbjct: 18 MKAVVLRSFGEAGNLKMETMPMPRPGRGEVLLRVHACGVCYHDVINRRGNL-PRTSVPAI 76 Query: 61 LGLEASGHVAELGPGCQGHWKIGDTAMAL-----------------------------LP 91 LG EA+G V E+GP G WK GD A L LP Sbjct: 77 LGHEAAGEVIEVGPDTPG-WKTGDRAATLQRMSCGDCALCRSGRNSLCKTDNRFFGEELP 135 Query: 92 GGGQAQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLS 151 GG AQ++ P G L +P L +AA + TA + G V+AG+ VLI Sbjct: 136 GG-YAQFMVAPVGGLGRVPASLPWNEAATVCCTTGTAVHTVRTRGKVRAGETVLITGASG 194 Query: 152 GVGTAAIQLTRMAGAIPLVTAGSQKKLQMAEKLGAAAGFNYKKEDFSEATLKFTKGAGVN 211 GVG +++QL R+ GA + S+ K+Q ++ GA + DF+ K T+GAGV+ Sbjct: 195 GVGLSSVQLARLDGARVIAVTSSEAKVQALKEAGADEVIVSRGLDFASDVRKRTQGAGVD 254 Query: 212 LILDCIGGSYWEKNVNCLALDGRWVLYGLMGGGDIN---GPLFSKLLFKRGSLITSLLRS 268 + ++ +G + +++ + +A GR V+ G + G + G + K L G+ T+ Sbjct: 255 VAVEIVGSATFDQTLKSMAPGGRVVVVGNLESGMVQLNPGLVIVKELEILGAYATT---- 310 Query: 269 RDNKYKQMLVNAFTEQILPHFSTEGPQRLLPVLDRIYPVTEIQEAHKYMEANKNIGKIVL 328 A ++ L +T G ++ V D + P+ E +AH +E + G++VL Sbjct: 311 ----------QAELDEALRLTATGGVRQF--VTDAV-PLAEAAKAHFRLENREVAGRLVL 357 Query: 329 ELPQ 332 P+ Sbjct: 358 VPPE 361 >4RVS-A nrPDB Length = 329 Score = 118 bits (295), Expect = 4e-27, Method: Compositional matrix adjust. Identities = 95/333 (28%), Positives = 153/333 (45%), Gaps = 12/333 (3%) Query: 1 MLAVHFDKPGGPENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNI 60 M A+ + GGP L + +P PG GE+L+K A +N D R GQY P + Sbjct: 2 MHAIEVTETGGPGVLRHVDQPQPQPGHGELLIKAEAIGVNFIDTYFRSGQY--PRELPFV 59 Query: 61 LGLEASGHVAELGPGCQGH---WKIGDTAMALLPGGGQAQYVTVPEGLLMPIPEGLTLTQ 117 +G E G V +GPG +GD ++ G A++ T P L +P+ +T Sbjct: 60 IGSEVCGTVEAVGPGVTAADTAISVGDRVVSASANGAYAEFCTAPASLTAKVPDDVTSEV 119 Query: 118 AAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKK 177 AA+ LTA LL V V+ GD VL+HAG GVG Q G + T + +K Sbjct: 120 AASALLKGLTAHYLLKSVYPVKRGDTVLVHAGAGGVGLILTQWATHLGVRVITTVSTAEK 179 Query: 178 LQMAEKLGAAAGFNYKKE--DFSEATLKFTKGAGVNLILDCIGGSYWEKNVNCLALDGRW 235 ++++ GA +Y ++ F+ + T G GV + D +G + ++ ++ LA+ G Sbjct: 180 AKLSKDAGADVVLDYPEDAWQFAGRVRELTGGTGVQAVYDGVGATTFDASLASLAVRGTL 239 Query: 236 VLYGLMGGGDINGPLFSKLLFKRGSLITSLLRSRDNKYKQMLVNAFTEQILPHFSTEGPQ 295 L+G G P+ + L GS+ L R + + F+ + F G + Sbjct: 240 ALFGAASGP--VPPVDPQRLNAAGSVY--LTRPSLFHFTRTG-EEFSWRAAELFDAIGNE 294 Query: 296 RLLPVLDRIYPVTEIQEAHKYMEANKNIGKIVL 328 + + YP+ + AH+ +EA K +G +VL Sbjct: 295 AITVAVGGRYPLADALRAHQDLEARKTVGSVVL 327 >1QOR-A nrPDB Length = 327 Score = 118 bits (295), Expect = 5e-27, Method: Compositional matrix adjust. Identities = 99/331 (29%), Positives = 152/331 (45%), Gaps = 16/331 (4%) Query: 4 VHFDKPGGPENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNILGL 63 + F K GGPE L E P E E+ ++ A +N D R G Y PPP + LG Sbjct: 5 IEFHKHGGPEVLQAVEFTPADPAENEIQVENKAIGINFIDTYIRSGLY-PPPSLPSGLGT 63 Query: 64 EASGHVAELGPGCQGHWKIGDT---AMALLPGGGQAQYVTVPEGLLMPIPEGLTLTQAAA 120 EA+G V+++G G + H K GD A + L + + ++P ++ QAAA Sbjct: 64 EAAGIVSKVGSGVK-HIKAGDRVVYAQSALGAYSSVHNIIADKAAILP--AAISFEQAAA 120 Query: 121 IPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQM 180 LT + LL ++ + L HA GVG A Q + GA + T G+ +K Q Sbjct: 121 SFLKGLTVYYLLRKTYEIKPDEQFLFHAAAGGVGLIACQWAKALGAKLIGTVGTAQKAQS 180 Query: 181 AEKLGAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIGGSYWEKNVNCLALDGRWVLYGL 240 A K GA NY++ED E + T G V ++ D +G WE++++CL G V +G Sbjct: 181 ALKAGAWQVINYREEDLVERLKEITGGKKVRVVYDSVGRDTWERSLDCLQRRGLMVSFG- 239 Query: 241 MGGGDINGPLFSKLLFKRGSLITSLLRSRDNKY---KQMLVNAFTEQILPHFSTEGPQRL 297 G + G +L ++GSL + R Y ++ L A E L G ++ Sbjct: 240 NSSGAVTGVNLG-ILNQKGSLYVT--RPSLQGYITTREELTEASNE--LFSLIASGVIKV 294 Query: 298 LPVLDRIYPVTEIQEAHKYMEANKNIGKIVL 328 + YP+ + Q AH+ +E+ G +L Sbjct: 295 DVAEQQKYPLKDAQRAHEILESRATQGSSLL 325 >3QWB-A nrPDB Length = 334 Score = 113 bits (283), Expect = 9e-26, Method: Compositional matrix adjust. Identities = 100/337 (29%), Positives = 162/337 (48%), Gaps = 28/337 (8%) Query: 7 DKPGGPENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNILGLEAS 66 D+ GG + + ++ PS E E+L+K + +N + R+G Y P +LG EAS Sbjct: 15 DEIGGYDVIKYEDYPVPSISEEELLIKNKYTGVNYIESYFRKGIY--PCEKPYVLGREAS 72 Query: 67 GHVAELGPGCQGHWKIGDTAMALLPGGGQAQYVTVP-EGLLMPIPEGLT---LTQAAAIP 122 G V G G ++++GD +A + AQY + +G +M +P+G + L AA Sbjct: 73 GTVVAKGKGVT-NFEVGDQ-VAYISNSTFAQYSKISSQGPVMKLPKGTSDEELKLYAAGL 130 Query: 123 EAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQMAE 182 LTA + +V+ GDYVL+ A GVG QL +M GA + A + +KL++A+ Sbjct: 131 LQVLTALSFTNEAYHVKKGDYVLLFAAAGGVGLILNQLLKMKGAHTIAVASTDEKLKIAK 190 Query: 183 KLGAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIGGSYWEKNVNCLALDGRWVLYGLMG 242 + GA N KED LKFT G GV+ D +G +E ++ L G +V +G Sbjct: 191 EYGAEYLINASKEDILRQVLKFTNGKGVDASFDSVGKDTFEISLAALKRKGVFVSFGNAS 250 Query: 243 GGDINGPLFS-------KLLFKRGSLITSLLRSRDNKYKQMLVNAFTEQILPHFSTEGPQ 295 G P FS + R L + + KY ++++ F + Sbjct: 251 GLI---PPFSITRLSPKNITLVRPQLYGYIADPEEWKY-------YSDEF---FGLVNSK 297 Query: 296 RLLPVLDRIYPVTEIQEAHKYMEANKNIGKIVLELPQ 332 +L + + YP+ + + A +E+ K +GK+VLE+PQ Sbjct: 298 KLNIKIYKTYPLRDYRTAAADIESRKTVGKLVLEIPQ 334 >1YB5-A nrPDB Length = 351 Score = 112 bits (279), Expect = 3e-25, Method: Compositional matrix adjust. Identities = 92/332 (27%), Positives = 158/332 (47%), Gaps = 12/332 (3%) Query: 1 MLAVHFDKPGGPENLYVK-EVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASN 59 M AV + GGPE L ++ ++A P P + +VL+KV A +N + R G Y P Sbjct: 30 MRAVRVFEFGGPEVLKLRSDIAVPIPKDHQVLIKVHACGVNPVETYIRSGTYSRKPLLPY 89 Query: 60 ILGLEASGHVAELGPGCQGHWKIGDTAMALLPGGGQAQYVTVPEGLLMPIPEGLTLTQAA 119 G + +G + +G K + GG A+Y + + +PE L Q A Sbjct: 90 TPGSDVAGVIEAVGDNASAFKKGDRVFTSSTISGGYAEYALAADHTVYKLPEKLDFKQGA 149 Query: 120 AIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQ 179 AI + TA++ L V+AG+ VL+H GVG AA Q+ R G L TAG+++ + Sbjct: 150 AIGIPYFTAYRALIHSACVKAGESVLVHGASGGVGLAACQIARAYGLKILGTAGTEEGQK 209 Query: 180 MAEKLGAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIGGSYWEKNVNCLALDGRWVLYG 239 + + GA FN+++ ++ + K+ G+++I++ + K+++ L+ GR ++ G Sbjct: 210 IVLQNGAHEVFNHREVNYIDKIKKYVGEKGIDIIIEMLANVNLSKDLSLLSHGGRVIVVG 269 Query: 240 LMGGGDINGPLFSKLLFKRGSLITSLLRSRDNKYKQMLVNAFTEQILPHFSTEGPQRLLP 299 G +IN P + K S+I L S + Q A + + L P Sbjct: 270 SRGTIEIN-P--RDTMAKESSIIGVTLFSSTKEEFQQYAAALQAGMEIGW-------LKP 319 Query: 300 VLDRIYPVTEIQEAHK-YMEANKNIGKIVLEL 330 V+ YP+ ++ EAH+ + + GK++L L Sbjct: 320 VIGSQYPLEKVAEAHENIIHGSGATGKMILLL 351 >2WEK-A nrPDB Length = 341 Score = 110 bits (276), Expect = 7e-25, Method: Compositional matrix adjust. Identities = 98/336 (29%), Positives = 148/336 (44%), Gaps = 38/336 (11%) Query: 18 KEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNILGLEASGHVAELGPGCQ 77 ++ P PG+G++L++ +N +D+ G+YDP +G E G V LG Sbjct: 23 RDCPVPLPGDGDLLVRNRFVGVNASDINYSAGRYDPSVKPPFDIGFEGIGEVVALGLSAS 82 Query: 78 GHWKIGDTAMALLPGGGQAQYVTVPEGLLMPI----PEGLTLTQAAAIPEAWLTAFQLLH 133 + +G A+A + G A+Y VP + P+ PE LTL + TA+ L Sbjct: 83 ARYTVGQ-AVAYMAPGSFAEYTVVPASIATPVPSVKPEYLTLLVSGT------TAYISLK 135 Query: 134 LVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQMAEKLGAAAGFNYK 193 +G + G VL+ A G G A+QL++ A + T S +K + LG NYK Sbjct: 136 ELGGLSEGKKVLVTAAAGGTGQFAMQLSKKAKCHVIGTCSSDEKSAFLKSLGCDRPINYK 195 Query: 194 KEDFSEATLKFTKGAGVNLILDCIGGSYWEKNVNCLALDGRWVLYGLMGGGDI------- 246 E LK GV+++ + +GG+ ++ V+ LA GR ++ G + G Sbjct: 196 TEPVG-TVLKQEYPEGVDVVYESVGGAMFDLAVDALATKGRLIVIGFISGYQTPTGLSPV 254 Query: 247 -NGPLFSKLLFKRGSLITSLLRSRDNKYK-------QMLVNA--FTEQILPHFSTEGPQR 296 G L +KLL K S+ L +KY+ +M V+ E L S EG Sbjct: 255 KAGTLPAKLLKKSASVQGFFLNHYLSKYQAAMSHLLEMCVSGDLVCEVDLGDLSPEG--- 311 Query: 297 LLPVLDRIYPVTEIQEAHKYMEANKNIGKIVLELPQ 332 R + I A YM KN GKIV+ELP Sbjct: 312 ------RFTGLESIFRAVNYMYMGKNTGKIVVELPH 341 >3TQH-A nrPDB Length = 321 Score = 107 bits (266), Expect = 1e-23, Method: Compositional matrix adjust. Identities = 99/342 (28%), Positives = 155/342 (45%), Gaps = 40/342 (11%) Query: 1 MLAVHFDKPGGPENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQG--------QYD 52 M A+ FD+ G P+ L + + P + ++L+KV A++LN D R G + + Sbjct: 7 MKAIQFDQFGPPKVLKLVDTPTPEYRKNQMLIKVHAASLNPIDYKTRNGSGFVAKKLKNN 66 Query: 53 PPPGASNILGLEASGHVAELGPGCQGHWKIGDTAMAL--LPG--GGQAQYVTVPEGLLMP 108 P G LG + SG V ELG + IGD M + P A+YV ++ Sbjct: 67 LPSG----LGYDFSGEVIELGSDVN-NVNIGDKVMGIAGFPDHPCCYAEYVCASPDTIIQ 121 Query: 109 IPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIP 168 E L+ QAA++P A LTA Q L+ V+ GD VLIHAG GVG AIQL + G Sbjct: 122 KLEKLSFLQAASLPTAGLTALQALNQ-AEVKQGDVVLIHAGAGGVGHLAIQLAKQKGT-T 179 Query: 169 LVTAGSQKKLQMAEKLGAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIGGSYWEKNVNC 228 ++T S++ + LGA NY +EDF A V+ ++D +GG ++++C Sbjct: 180 VITTASKRNHAFLKALGAEQCINYHEEDFLLAI-----STPVDAVIDLVGGDVGIQSIDC 234 Query: 229 LALDGRWVLYGLMGGGDINGPLFSKLLFKRGSLITSLLRSRDNKYKQMLVNAFTEQILPH 288 L G V + G + +K +R + + Y LV+ Sbjct: 235 LKETGCIVSVPTITAGRVIE--VAKQKHRRAFGLLKQFNIEELHYLGKLVS--------- 283 Query: 289 FSTEGPQRLLPVLDRIYPVTEIQEAHKYMEANKNIGKIVLEL 330 +L + RI+ ++E AH+ +E GK+V ++ Sbjct: 284 -----EDKLRIEISRIFQLSEAVTAHELLETGHVRGKLVFKV 320 >4J6F-A nrPDB Length = 382 Score = 105 bits (261), Expect = 3e-23, Method: Compositional matrix adjust. Identities = 99/363 (27%), Positives = 158/363 (43%), Gaps = 52/363 (14%) Query: 1 MLAVHFDKPGGPENL-YVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQY---DPPPG 56 M AV GG E L Y ++V P+P GEVL+KV A +N D+ R+G Y D P Sbjct: 34 MTAVLLTGHGGLEKLVYSRDVPVPAPAAGEVLIKVTACGMNNTDVWVREGAYGTEDDPSA 93 Query: 57 ASN------------ILGLEASGHVAELGPGCQGHWKIGDTAMALLP------------- 91 S I G + GH+ +G G +IG+ M Sbjct: 94 VSTWRRHGNTLTFPRIQGTDTVGHIVAVGEGVD-RARIGERVMVDFSIYNRDDDSLADID 152 Query: 92 ------GGGQAQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVL 145 GG A+Y+ +P + LT + A A+LT ++L + AG+ VL Sbjct: 153 YMGHGRDGGYAEYMALPAENAHVVATDLTDIELATFCCAYLTGERMLER-ARLAAGETVL 211 Query: 146 IHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQMAEKLGAAAGFNYKKEDFSEATLKFT 205 + GVG+A IQL R GA+P+ AG K+ M + +GA A + D +EA + Sbjct: 212 VTGASGGVGSAIIQLARARGAVPIAVAGPGKEAAMLD-IGAQAVVTRGQGDLAEAVEAAS 270 Query: 206 KGAGVNLILDCIGGSYWEKNVNCLALDGRWVLYGLMGGGDINGPLFSKLLFKRGSLITSL 265 G ++++ D +GG + + L +GR+ G + G + L + + K+ L S Sbjct: 271 GGRPIDVVADLVGGPLFNDLLKILRPEGRYTTAGAIAGPVVQLDLRT-MYLKQLELHGSS 329 Query: 266 LRSRDNKYKQMLVNAFTEQILPHFSTEGPQRLLPVLDRIYPVTEIQEAHKYMEANKNIGK 325 SR + + LV E +++ P++ +YP++E A A +GK Sbjct: 330 QGSRADFRR--LVRYIEE-----------KKIRPLVGGVYPLSEFHRAQTDFMAKNFVGK 376 Query: 326 IVL 328 +V+ Sbjct: 377 LVV 379 >3UOG-A nrPDB Length = 363 Score = 100 bits (250), Expect = 6e-22, Method: Compositional matrix adjust. Identities = 93/343 (27%), Positives = 159/343 (46%), Gaps = 41/343 (11%) Query: 12 PENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNILGLEASGHVAE 71 P +L + E P GE +++++ A +LN D + + + + SG V Sbjct: 38 PHDLKLAERPVPEAGEHDIIVRTLAVSLNYRDKLVLETGMGLDLAFPFVPASDMSGVVEA 97 Query: 72 LGPGCQGHWKIGDTAMA---------LLPGGGQ---------------AQYVTVPEGLLM 107 +G ++ GD ++ L PG G+ ++YV +PEG + Sbjct: 98 VGKSVT-RFRPGDRVISTFAPGWLDGLRPGTGRTPAYETLGGAHPGVLSEYVVLPEGWFV 156 Query: 108 PIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAI 167 P+ L +A+ +P A LTA+ L G+++AGD V++ G GV +Q+ + GA Sbjct: 157 AAPKSLDAAEASTLPCAGLTAWFALVEKGHLRAGDRVVVQ-GTGGVALFGLQIAKATGAE 215 Query: 168 PLVTAGSQKKLQMAEKLGAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIGGSYWEKNVN 227 +VT+ S++KL A LGA G N +ED+ E T G + IL+ GG+ +++ Sbjct: 216 VIVTSSSREKLDRAFALGADHGINRLEEDWVERVYALTGDRGADHILEIAGGAGLGQSLK 275 Query: 228 CLALDGRWVLYGLMGGGDINGPLFSKLLFKRGSLITSLLRSRDNKYKQMLVNAFTEQILP 287 +A DGR + G++ G +++GP+ LL K S + + + + LV A Sbjct: 276 AVAPDGRISVIGVLEGFEVSGPV-GPLLLK--SPVVQGISVGHRRALEDLVGAVDR---- 328 Query: 288 HFSTEGPQRLLPVLDRIYPVTEIQEAHKYMEANKNIGKIVLEL 330 L PV+D Y TE+ EA +++ GK+V+E Sbjct: 329 -------LGLKPVIDMRYKFTEVPEALAHLDRGP-FGKVVIEF 363 >3JYN-A nrPDB Length = 325 Score = 96.3 bits (238), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 74/241 (30%), Positives = 114/241 (47%), Gaps = 3/241 (1%) Query: 4 VHFDKPGGPENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNILGL 63 + F GGPE L + +PG V+++ A LN D R G Y P P + LG Sbjct: 5 IQFSTVGGPEVLEYVDFEPEAPGPQAVVVRNKAIGLNFIDTYYRSGLY-PAPFLPSGLGA 63 Query: 64 EASGHVAELGPGCQGHWKIGD-TAMALLPGGGQAQYVTVPEGLLMPIPEGLTLTQAAAIP 122 E +G V +G +K+GD A P G ++ +PE L+ + + ++ QAAA+ Sbjct: 64 EGAGVVEAVGDEVT-RFKVGDRVAYGTGPLGAYSEVHVLPEANLVKLADSVSFEQAAALM 122 Query: 123 EAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQMAE 182 LT LL V+ G+ +L HA GVG+ A Q + GA + T S +K A+ Sbjct: 123 LKGLTVQYLLRQTYQVKPGEIILFHAAAGGVGSLACQWAKALGAKLIGTVSSPEKAAHAK 182 Query: 183 KLGAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIGGSYWEKNVNCLALDGRWVLYGLMG 242 LGA +Y ED ++ L+ T G ++ D +G W +++ +A G V +G Sbjct: 183 ALGAWETIDYSHEDVAKRVLELTDGKKCPVVYDGVGQDTWLTSLDSVAPRGLVVSFGNAS 242 Query: 243 G 243 G Sbjct: 243 G 243 >3SLK-A nrPDB Length = 795 Score = 93.6 bits (231), Expect = 1e-19, Method: Compositional matrix adjust. Identities = 95/334 (28%), Positives = 155/334 (46%), Gaps = 36/334 (10%) Query: 8 KPGGPENL-YVKEVAKPSP-GEGEVLLKVAASALNRADLMQRQGQYDPPPGASNILGLEA 65 +PG + L V E +P G+GEV + + A+ +N D + G Y PG ++ LG E Sbjct: 217 RPGSLDGLALVDEPTATAPLGDGEVRIAMRAAGVNFRDALIALGMY---PGVAS-LGSEG 272 Query: 66 SGHVAELGPGCQGHWKIGDTAMALLPGGGQAQYVTVPEGLLMPIPEGLTLTQAAAIPEAW 125 +G V E GPG G GD M ++P ++ IP G + +AA++P + Sbjct: 273 AGVVVETGPGVTG-LAPGDRVMGMIPKA-FGPLAVADHRMVTRIPAGWSFARAASVPIVF 330 Query: 126 LTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQMAEKLG 185 LTA+ L + ++ G+ +L+H+ GVG AAIQL R GA TA S+ K Q E L Sbjct: 331 LTAYYALVDLAGLRPGESLLVHSAAGGVGMAAIQLARHLGAEVYATA-SEDKWQAVE-LS 388 Query: 186 AAAGFNYKKEDFSEATLKFTKGAGVNLILDCIGGSYWEKNVNCLALDGRWVLYGLMGGGD 245 + + DF + L T G GV+++L+ + G + + ++ L GR++ +G D Sbjct: 389 REHLASSRTCDFEQQFLGATGGRGVDVVLNSLAGEFADASLRMLPRGGRFL---ELGKTD 445 Query: 246 INGPL--------FSKLLFKRGSLITSLLRSRDNKYKQMLVNAFTEQILPHFSTEGPQRL 297 + P+ S F R + LV F ++L Sbjct: 446 VRDPVEVADAHPGVSYQAFD----TVEAGPQRIGEMLHELVELFEGRVL---------EP 492 Query: 298 LPVLDRIYPVTEIQEAHKYMEANKNIGKIVLELP 331 LPV + V + EA +++ +++GK+VL +P Sbjct: 493 LPVT--AWDVRQAPEALRHLSQARHVGKLVLTMP 524 >4EYE-A nrPDB Length = 342 Score = 85.1 bits (209), Expect = 4e-17, Method: Compositional matrix adjust. Identities = 97/336 (28%), Positives = 156/336 (46%), Gaps = 25/336 (7%) Query: 1 MLAVHFDKPGGPENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQY----DPPPG 56 M A+ GPE L +V P G V++ V A+ + D + +G+Y +PP Sbjct: 22 MKAIQAQSLSGPEGLVYTDVETPGAGPNVVVVDVKAAGVCFPDYLMTKGEYQLKMEPP-- 79 Query: 57 ASNILGLEASGHVAELGPGCQGHWKIGDTAMALLPGGGQAQYVTVPEGLLMPIPEGLTLT 116 + G+E +G V G K GD MA GG A+ V V ++P P L Sbjct: 80 --FVPGIETAGVVRSAPEGS--GIKPGDRVMAFNFIGGYAERVAVAPSNILPTPPQLDDA 135 Query: 117 QAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQK 176 +A A+ + T + G ++AG+ VL+ G+GTAAIQ+ + GA + Sbjct: 136 EAVALIANYHTMYFAYARRGQLRAGETVLVLGAAGGIGTAAIQIAKGMGAKVIAVVNRTA 195 Query: 177 KLQMAEKLGAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIGGSYWEKNVNCLALDGRWV 236 + + +GA +E +++A + T GAGV++++D IGG ++ V LA +GR + Sbjct: 196 ATEFVKSVGADIVLPL-EEGWAKAVREATGGAGVDMVVDPIGGPAFDDAVRTLASEGRLL 254 Query: 237 LYGLMGGGDINGPLFSKLLFKRGSLI----TSLLRSRDNKYKQMLVNAFTEQILPHFSTE 292 + G GG I ++LL + SLI LR+ + + T+ L E Sbjct: 255 VVGFAAGG-IPTIKVNRLLLRNASLIGVAWGEFLRTHADYLYE------TQAGLEKLVAE 307 Query: 293 GPQRLLPVLDRIYPVTEIQEAHKYMEANKNIGKIVL 328 G + PV RI P++E ++A + K GK+VL Sbjct: 308 GMRP--PVSARI-PLSEGRQALQDFADGKVYGKMVL 340 >4IDE-A nrPDB Length = 332 Score = 80.1 bits (196), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 92/322 (28%), Positives = 149/322 (46%), Gaps = 50/322 (15%) Query: 20 VAKPSPGEGEVLLKVAASALNRADLMQRQGQY-DPPPGASNILGLEASGHVAELGPGCQG 78 VA P E +VL+KV A++LN D + G + D I G + +G V ++G Sbjct: 45 VAVPEIKEDQVLIKVVAASLNPVDFKRALGYFKDTDSPLPTIPGYDVAGVVVKVGSQVT- 103 Query: 79 HWKIGDTAMALLPG---------GGQAQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAF 129 +K+GD L G A+Y E +L P+ L+ +AA++P A TA Sbjct: 104 KFKVGDEVYGDLNETALVNPTRFGSLAEYTAADERVLAHKPKNLSFIEAASLPLAIETAH 163 Query: 130 QLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTR-MAGAIPLVTAGSQKKLQMAEKLGAAA 188 + L + AG VL+ G GVGT IQL + + GA + S KKL + LGA Sbjct: 164 EGLER-AELSAGKSVLVLGGAGGVGTHIIQLAKHVFGASKVAATASTKKLDLLRTLGADL 222 Query: 189 GFNYKKEDFSEATLKFTKGAGVNLILDCIGGSYWEKNVNCLALDGRWVLYGLMGGGDING 248 +Y KE+F + KF +++ D +G + +K V + G+ V ++G Sbjct: 223 AIDYTKENFEDLPEKF------DVVYDAVGET--DKAVKAVKEGGKVVT--IVGPATPPA 272 Query: 249 PLFSKLLFKRGSLITSLLRSRDNKYKQMLVNAFTEQILPHFSTEGPQRLLPVLDRI--YP 306 LF +L +GS++ E++ P+ + ++ PVLD YP Sbjct: 273 ILF--VLTSKGSVL--------------------EKLKPYLES---GKVKPVLDPTSPYP 307 Query: 307 VTEIQEAHKYMEANKNIGKIVL 328 T++ EA Y+E+++ GK+V+ Sbjct: 308 FTKVVEAFGYLESSRATGKVVV 329 >3PII-A nrPDB Length = 339 Score = 80.1 bits (196), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 91/347 (26%), Positives = 150/347 (43%), Gaps = 50/347 (14%) Query: 13 ENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNILGLEASGHVAEL 72 E L +KEV KP+ GEVL+++ A + DL G + P I G E G V E+ Sbjct: 11 EPLKIKEVEKPTISYGEVLVRIKACGVCHTDLHAAHGDWPVKPKLPLIPGHEGVGIVEEV 70 Query: 73 GPGCQGHWKIGDT------------AMALLPG----------------GGQAQYVTVPEG 104 GPG H K+GD L G GG A+Y Sbjct: 71 GPGVT-HLKVGDRVGIPWLYSACGHCDYCLSGQETLCEHQKNAGYSVDGGYAEYCRAAAD 129 Query: 105 LLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMA 164 ++ IP+ L+ +AA I A +T ++ L + G + G++V I+ G+ G G A+Q + Sbjct: 130 YVVKIPDNLSFEEAAPIFCAGVTTYKALKVTG-AKPGEWVAIY-GIGGFGHVAVQYAKAM 187 Query: 165 GAIPLVTAGSQKKLQMAEKLGAAAGFNYKKEDFSEATLKFTKGAGVN-LILDCIGGSYWE 223 G + +KL++A++LGA N KED A K GV+ ++ + ++ Sbjct: 188 GLNVVAVDIGDEKLELAKELGADLVVNPLKED--AAKFMKEKVGGVHAAVVTAVSKPAFQ 245 Query: 224 KNVNCLALDGRWVLYGLMGGGDINGPLFSKLLFKRGSLITSLLRSRDNKYKQMLVNAFTE 283 N + G VL GL ++ P+F +L +I S++ +R + + + Sbjct: 246 SAYNSIRRGGACVLVGLP-PEEMPIPIFDTVL-NGIKIIGSIVGTRKDLQEAL------- 296 Query: 284 QILPHFSTEGPQRLLPVLDRIYPVTEIQEAHKYMEANKNIGKIVLEL 330 F+ EG + + + P+ +I E M + G++VL L Sbjct: 297 ----QFAAEGKVK---TIIEVQPLEKINEVFDRMLKGQINGRVVLTL 336 >5A3V-A nrPDB Length = 329 Score = 77.4 bits (189), Expect = 7e-15, Method: Compositional matrix adjust. Identities = 94/341 (27%), Positives = 155/341 (45%), Gaps = 49/341 (14%) Query: 10 GGPENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDP--PPGASNILGLEASG 67 GG L +V P+P EV LK+ A++LN D ++G P P I + +G Sbjct: 16 GGAAGLEHVQVPVPTPKSNEVCLKLEATSLNPVDWKIQKGMIRPFLPRKFPCIPATDVAG 75 Query: 68 HVAELGPGCQGHWKIGDTAMALLP---GGGQAQYVTVPEGLLMPIPEGLTLTQAAAIPEA 124 V E+G G + ++K GD +A+L GGG A++ E L + P+ + +AAA+P A Sbjct: 76 EVVEVGSGVK-NFKAGDKVVAVLSHLGGGGLAEFAVATEKLTVKRPQEVGAAEAAALPVA 134 Query: 125 WLTAFQL------LHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKL 178 LTA Q L L G + + +L+ A GVG A+QL ++A A T G+ + + Sbjct: 135 GLTALQALTNPAGLKLDGTGKKAN-ILVTAASGGVGHYAVQLAKLANAHVTATCGA-RNI 192 Query: 179 QMAEKLGAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIGG---SYWEKNVNCLALDGRW 235 + + LGA +YK + A LK G + ++ C G S +E N L+ +G+ Sbjct: 193 EFVKSLGADEVLDYKTPE--GAALKSPSGKKYDAVVHCANGIPFSVFEPN---LSENGKV 247 Query: 236 VLYGLMGGGDIN-GP------LFSKLLFKRGSLITSLLRSRDNKYKQMLVNAFTEQILPH 288 + DI GP K+ + L+ LL + + +VN E Sbjct: 248 I--------DITPGPNAMWTYAVKKITMSKKQLVPLLLIPKAENL-EFMVNLVKE----- 293 Query: 289 FSTEGPQRLLPVLDRIYPVTEIQEAHKYMEANKNIGKIVLE 329 ++ V+D +P+++ ++A GKI++E Sbjct: 294 ------GKVKTVIDSKHPLSKAEDAWAKSIDGHATGKIIVE 328 >3FBG-A nrPDB Length = 346 Score = 73.9 bits (180), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 79/337 (23%), Positives = 141/337 (41%), Gaps = 52/337 (15%) Query: 23 PSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNILGLEASGHVAELGPGCQGHWKI 82 P P E+L+K+ + ++N D QR P +LG +A G V +G + Sbjct: 28 PEPKVHEILVKIQSISVNPVDTKQRLMDVSKAP---RVLGFDAIGVVESVGNEVT-MFNQ 83 Query: 83 GDTAM---ALLPGGGQAQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLV---- 135 GD + G A+Y + E L+ P+ ++ QA ++P +TA++ L V Sbjct: 84 GDIVYYSGSPDQNGSNAEYQLINERLVAKAPKNISAEQAVSLPLTGITAYETLFDVFGIS 143 Query: 136 --GNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQMAEKLGAAAGFNYK 193 N G +LI G GVG+ A Q+ + G + TA + ++ +K+GA N+K Sbjct: 144 RNRNENEGKTLLIINGAGGVGSIATQIAKAYGLRVITTASRNETIEWTKKMGADIVLNHK 203 Query: 194 KEDFSEATLKFTKGAGVNLI--LDCIGGS--YWEKNVNCLALDGRW-VLYGLMGGGDING 248 E+ L K G+ L+ + C + Y++ + + G + D+N Sbjct: 204 -----ESLLNQFKTQGIELVDYVFCTFNTDMYYDDMIQLVKPRGHIATIVAFENDQDLNA 258 Query: 249 P-----------LFSKLLFKRGSLIT--SLLRSRDNKYKQMLVNAFTEQILPHFSTEGPQ 295 +F++ L + +I L NK +Q + T +++ +TE Sbjct: 259 LKPKSLSFSHEFMFARPLNQTDDMIKHHEYLEDITNKVEQNIYQPTTTKVIEGLTTEN-- 316 Query: 296 RLLPVLDRIYPVTEIQEAHKYMEANKNIGKIVLELPQ 332 I +AH+ +E+N IGK+V+ L + Sbjct: 317 --------------IYQAHQILESNTMIGKLVINLNE 339 >5ENV-A nrPDB Length = 347 Score = 73.6 bits (179), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 85/347 (24%), Positives = 144/347 (41%), Gaps = 46/347 (13%) Query: 15 LYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNILGLEASGHVAELGP 74 L K++ P P E+L+ V S + DL G + P + G E +G V +G Sbjct: 18 LEYKDIPVPKPKANELLINVKYSGVCHTDLHAWHGDWPLPVKLPLVGGHEGAGVVVGMGE 77 Query: 75 GCQGHWKIGDTA------------------------MALLPG----GGQAQYVTVPEGLL 106 +G WKIGD A A L G G QY T Sbjct: 78 NVKG-WKIGDYAGIKWLNGSCMACEYCELGNESNCPHADLSGYTHDGSFQQYATADAVQA 136 Query: 107 MPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGA 166 IP+G L Q A I A +T ++ L N+ AG +V I G+G+ A+Q + G Sbjct: 137 AHIPQGTDLAQVAPILCAGITVYKALK-SANLMAGHWVAISGAAGGLGSLAVQYAKAMGY 195 Query: 167 IPLVTAGSQKKLQMAEKLGAAAGFNYKKE-DFSEATLKFTKGAGVNLILDCIGGSYWEKN 225 L G + K ++ +G ++ KE D A LK T G +I + + E + Sbjct: 196 RVLGIDGGEGKEELFRSIGGEVFIDFTKEKDIVGAVLKATDGGAHGVINVSVSEAAIEAS 255 Query: 226 VNCLALDGRWVLYGLMGGGDINGPLFSKLLFKRGSLITSLLRSRDNKYKQMLVNAFTEQI 285 + +G VL G+ G +F++++ K S++ S + +R A T + Sbjct: 256 TRYVRANGTTVLVGMPAGAKCCSDVFNQVV-KSISIVGSYVGNR----------ADTREA 304 Query: 286 LPHFSTEGPQRLLPVLDRIYPVTEIQEAHKYMEANKNIGKIVLELPQ 332 L F+ + L+ ++ ++ + E ++ ME + +G+ V++ + Sbjct: 305 LDFFA----RGLVKSPIKVVGLSTLPEIYEKMEKGQIVGRYVVDTSK 347 >1LLU-A nrPDB Length = 342 Score = 72.8 bits (177), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 90/347 (25%), Positives = 149/347 (42%), Gaps = 54/347 (15%) Query: 15 LYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNILGLEASGHVAELGP 74 L ++EV P PG G+VL+K+ AS + DL +G + P I G E G+VA +G Sbjct: 19 LRIEEVKVPLPGPGQVLVKIEASGVCHTDLHAAEGDWPVKPPLPFIPGHEGVGYVAAVGS 78 Query: 75 G--------------------CQGHWKIG---------DTAMALLPGGGQAQYVTVPEGL 105 G C H G +T ++ GG A+YV Sbjct: 79 GVTRVKEGDRVGIPWLYTACGCCEHCLTGWETLCESQQNTGYSV--NGGYAEYVLADPNY 136 Query: 106 LMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAG 165 + +P+ + + A I A +T ++ L N + G +V I +G+ G+G A+Q R G Sbjct: 137 VGILPKNVEFAEIAPILCAGVTVYKGLKQT-NARPGQWVAI-SGIGGLGHVAVQYARAMG 194 Query: 166 AIPLVTAGSQKKLQMAEKLGAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIGGSYWEKN 225 KL++A KLGA+ N ++ED EA + GA +++ + S + + Sbjct: 195 LHVAAIDIDDAKLELARKLGASLTVNARQEDPVEAIQRDIGGAH-GVLVTAVSNSAFGQA 253 Query: 226 VNCLALDGRWVLYGLMGGGDINGPLFSKLLFKRGSLITSLLRSRDNKYKQMLVNAFTEQI 285 + G L GL GD P+F ++ K + S++ +R + + + Sbjct: 254 IGMARRGGTIALVGLP-PGDFPTPIFD-VVLKGLHIAGSIVGTRADLQEAL--------- 302 Query: 286 LPHFSTEGPQRLLPVLDRIYP--VTEIQEAHKYMEANKNIGKIVLEL 330 F+ EG V I+P + +I + M A + G+IVLE+ Sbjct: 303 --DFAGEG-----LVKATIHPGKLDDINQILDQMRAGQIEGRIVLEM 342 >3B70-A nrPDB Length = 371 Score = 72.4 bits (176), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 68/236 (28%), Positives = 104/236 (44%), Gaps = 31/236 (13%) Query: 21 AKPSP--GEGEVLLKVAASALNRADLMQRQGQYDPPPGASNILGLEASGHVAELGPGCQG 78 A P P +V ++V A A+N +D R GQ+ P LG + +G V +G Sbjct: 28 AAPCPMLPRDQVYVRVEAVAINPSDTKMR-GQFATP---WAFLGTDYAGTVVAVGSDVT- 82 Query: 79 HWKIGDTAMA----LLPG----GGQAQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTA-- 128 H ++GD + P G +QY + IP+GL+ QAAA+P TA Sbjct: 83 HIQVGDRVYGAQNEMCPRTPDQGAFSQYTVTRGRVWAKIPKGLSFEQAAALPAGISTAGL 142 Query: 129 -FQLLHLVGNVQAGD---------YVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKL 178 +LL L + D YVL++ G + T +Q+ R++G IP+ T S Sbjct: 143 AMKLLGLPLPSPSADQPPTHSKPVYVLVYGGSTATATVTMQMLRLSGYIPIATC-SPHNF 201 Query: 179 QMAEKLGAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIGGSYWEKNVNCLALDGR 234 +A+ GA F+Y+ + ++ +TK + LDCI E C A GR Sbjct: 202 DLAKSRGAEEVFDYRAPNLAQTIRTYTKN-NLRYALDCITNV--ESTTFCFAAIGR 254 >4DVJ-A nrPDB Length = 363 Score = 70.9 bits (172), Expect = 7e-13, Method: Compositional matrix adjust. Identities = 91/353 (25%), Positives = 161/353 (45%), Gaps = 42/353 (11%) Query: 1 MLAVHFDKPG---GPENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGA 57 M AV ++KP +L E+ KP+P ++L++V A ++N D R+ PP G Sbjct: 23 MKAVGYNKPAPITDDASLLDIELPKPAPAGHDILVEVKAVSVNPVDYKVRRST--PPDGT 80 Query: 58 S-NILGLEASGHVAELGPGCQGHWKIGDT---AMALLPGGGQAQYVTVPEGLLMPIPEGL 113 ++G +A+G V+ +GP ++ GD A +++ G A++ V E ++ P+ L Sbjct: 81 DWKVIGYDAAGIVSAVGPDVT-LFRPGDEVFYAGSIIRPGTNAEFHLVDERIVGRKPKTL 139 Query: 114 TLTQAAAIP----EAWLTAFQLLHLVGNVQ-AGDYVLIHAGLSGVGTAAIQLTRMAGAIP 168 +AAA+P AW F L + V A +LI G GVG+ A+Q+ R + Sbjct: 140 DWAEAAALPLTSITAWEAFFDRLDVNKPVPGAAPAILIVGGAGGVGSIAVQIARQRTDLT 199 Query: 169 LVTAGSQKKLQ-MAEKLGAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIGGSYWEKNVN 227 ++ S+ + Q + LGA ++ K +E GA + + + + Sbjct: 200 VIATASRPETQEWVKSLGAHHVIDHSKPLAAEVA-ALGLGAPAFVFSTTHTDKHAAEIAD 258 Query: 228 CLALDGRWVLYGLMGGGDINGP-LFSKLLFKRG--SLITSLLRSR------DNKYKQMLV 278 +A GR+ L I+ P F +LFKR S+ L+ +R D + L+ Sbjct: 259 LIAPQGRFCL--------IDDPSAFDIMLFKRKAVSIHHELMFTRPMFGTPDMSEQGRLL 310 Query: 279 NAFTEQILPHFSTEGPQRLLPVLDRIYPVT--EIQEAHKYMEANKNIGKIVLE 329 N + + EG R + +R+ P+ +++AH +E+ GK+V+E Sbjct: 311 NDVSRLV-----DEGRLRTT-LTNRLSPINAANLKQAHALVESGTARGKVVIE 357 >3MEQ-A nrPDB Length = 365 Score = 67.8 bits (164), Expect = 6e-12, Method: Compositional matrix adjust. Identities = 86/324 (26%), Positives = 134/324 (41%), Gaps = 48/324 (14%) Query: 6 FDKPGGPENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNILGLEA 65 F KP L + EV P PG G++ + + AS + DL +G + P I G E Sbjct: 34 FGKP-----LTIDEVPIPQPGPGQIQVAIQASGVCHTDLHAAEGDWPVKPNPPFIPGHEG 88 Query: 66 SGHVAELGPGCQGHWKIGD--------TAMA----LLPG----------------GGQAQ 97 G V+ +G G + H K GD TA L G GG A+ Sbjct: 89 VGFVSAVGSGVK-HVKEGDRVGIPWLYTACGHCRHCLGGWETLCEEQLNTGYSVNGGFAE 147 Query: 98 YVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAA 157 YV + +P+ + + A + A +T ++ L V + + GD+V+I +G+ G+G A Sbjct: 148 YVVADPNFVGHLPKNIDFNEIAPVLCAGVTVYKGLK-VTDTKPGDWVVI-SGIGGLGHMA 205 Query: 158 IQLTRMAGAIPLVTAGSQKKLQMAEKLGAAAGFNYKK-EDFSEATLKFTKGAGVNLILDC 216 +Q R G +KL +A +LGA N K D + K T G +++ Sbjct: 206 VQYARAMGLNVAAVDIDDRKLDLARRLGATVTVNAKTVADPAAYIRKETDGGAQGVLVTA 265 Query: 217 IGGSYWEKNVNCLALDGRWVLYGLMGGGDINGPLFSKLL---FKRGSLI-------TSLL 266 + +E+ + +A G L GL GD +F+ +L RGS++ SL Sbjct: 266 VSPKAFEQALGMVARGGTVSLNGLP-PGDFPLSIFNMVLNGVTVRGSIVGTRLDLQESLD 324 Query: 267 RSRDNKYKQMLVNAFTEQILPHFS 290 + D K K + E I F Sbjct: 325 FAADGKVKATIQTGKLEDINAIFD 348 >2VN8-A nrPDB Length = 375 Score = 66.6 bits (161), Expect = 1e-11, Method: Compositional matrix adjust. Identities = 69/213 (32%), Positives = 100/213 (46%), Gaps = 26/213 (12%) Query: 29 EVLLKVAASALNRADLMQRQG--------QYDPPPGASN------ILGLEASGHVAELGP 74 EV++KV A+++N D+ R G + DP LG + SG V E G Sbjct: 52 EVIVKVHAASVNPIDVNMRSGYGATALNMKRDPLHVKIKGEEFPLTLGRDVSGVVMECGL 111 Query: 75 GCQGHWKIGDTAMALLP---GGGQAQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQL 131 + ++K GD A +P G +++V V + P+ LT TQAA++P LTA+ Sbjct: 112 DVK-YFKPGDEVWAAVPPWKQGTLSEFVVVSGNEVSHKPKSLTHTQAASLPYVALTAWSA 170 Query: 132 LHLVGNVQ----AGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQMAEKLGAA 187 ++ VG + G VLI GVGT AIQ+ + A + SQ ++ KLGA Sbjct: 171 INKVGGLNDKNCTGKRVLILGASGGVGTFAIQVMKAWDA-HVTAVCSQDASELVRKLGAD 229 Query: 188 AGFNYKKEDFSEATLKFTKGAGVNLILDCIGGS 220 +YK E LK K + ILD +GGS Sbjct: 230 DVIDYKSGSVEE-QLKSLK--PFDFILDNVGGS 259 >4Z6K-A nrPDB Length = 346 Score = 64.3 bits (155), Expect = 7e-11, Method: Compositional matrix adjust. Identities = 73/289 (25%), Positives = 122/289 (42%), Gaps = 34/289 (11%) Query: 13 ENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNILGLEASGHVAEL 72 ++L ++EV P+PG GE+++K+ AS + DL +G + P I G E G + + Sbjct: 11 QSLQIEEVDIPTPGAGEIVVKMQASGVCHTDLHAVEGDWPVKPSPPFIPGHEGVGLITAV 70 Query: 73 GPG------------------------CQGHWKI---GDTAMALLPGGGQAQYVTVPEGL 105 G G C G W+ G A+YV Sbjct: 71 GEGVTHVKEGDRVGVAWLYSACGHCTHCLGGWETLCESQQNSGYSVNGSFAEYVLANANY 130 Query: 106 LMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAG 165 + IPE + + A + A +T ++ L + + + GD+V+I +G+ G+G A+Q G Sbjct: 131 VGIIPESVDSIEIAPVLCAGVTVYKGLKMT-DTKPGDWVVI-SGIGGLGHMAVQYAIAMG 188 Query: 166 AIPLVTAGSQKKLQMAEKLGAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIGGSYWEKN 225 KL A+KLGA N K D +E K GA L+ + +++ Sbjct: 189 LNVAAVDIDDDKLAFAKKLGAKVTVNAKNTDPAEYLQKEIGGAHGALVT-AVSAKAFDQA 247 Query: 226 VNCLALDGRWVLYGLMGGGDINGPLFSKLL---FKRGSLITSLLRSRDN 271 ++ L G V GL GD +F +L RGS++ + L +++ Sbjct: 248 LSMLRRGGTLVCNGLP-PGDFPVSIFDTVLNGITIRGSIVGTRLDLQES 295 >4A10-A nrPDB Length = 447 Score = 64.3 bits (155), Expect = 7e-11, Method: Compositional matrix adjust. Identities = 90/383 (23%), Positives = 150/383 (39%), Gaps = 86/383 (22%) Query: 13 ENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQ----------------RQG----QYD 52 ++L + EV P EVL+ V AS++N + RQG ++D Sbjct: 48 KSLRLGEVPMPELAPDEVLVAVMASSINYNTVWSAMFEPIPTFHFLKQNARQGGWATRHD 107 Query: 53 PPPGASNILGLEASGHVAELGPGCQGHWKIGDTAMALLPG-------------------- 92 P ++LG + SG V G G + WK GD + + P Sbjct: 108 QP---YHVLGSDCSGVVVRTGIGVR-RWKPGDHVI-VHPAHVDEQEPATHGDGMLGTEQR 162 Query: 93 --------GGQAQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLL--HLVGNVQAGD 142 GG A+Y V L+P P LT +AA P TA+++L ++ GD Sbjct: 163 AWGFETNFGGLAEYGVVRASQLLPKPAHLTWEEAAVSPLCAGTAYRMLVSDRGAQMKQGD 222 Query: 143 YVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQMAEKLGAAAGFNYKK----EDFS 198 VLI G+G+ AIQ + G IP+ S +K LG N + +D + Sbjct: 223 IVLIWGASGGLGSYAIQFVKNGGGIPVAVVSSAQKEAAVRALGCDLVINRAELGITDDIA 282 Query: 199 EATLKFTKGAGVNLILDCIGGSYWEKNVNCLALDGRWVLYGLMGGGDINGPLFSKLLFKR 258 + + + G L + + E ++ GR V +GL S ++ +R Sbjct: 283 DDPRRVVE-TGRKLAKLVVEKAGREPDI-VFEHTGR-VTFGL-----------SVIVARR 328 Query: 259 GSLITSL------LRSRDNKYKQMLVNAFT-EQILPHFSTEGPQRL------LPVLDRIY 305 G + + L + DN+Y M + H + RL +P + +Y Sbjct: 329 GGTVVTCGSSSGYLHTFDNRYLWMKLKKIVGSHGANHEEQQATNRLFESGAVVPAMSAVY 388 Query: 306 PVTEIQEAHKYMEANKNIGKIVL 328 P+ E EA + ++ ++ +GK+ + Sbjct: 389 PLAEAAEACRVVQTSRQVGKVAV 411 >2DFV-A nrPDB Length = 347 Score = 63.5 bits (153), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 82/293 (27%), Positives = 126/293 (43%), Gaps = 49/293 (16%) Query: 1 MLAVHFDKPGGPENLYVKEVAKPSPGEGEVLLKVAASALNRADLM------QRQGQYDPP 54 M+A+ KPG L EV P PG GEVL+KV A+++ DL Q + PP Sbjct: 4 MVAIMKTKPGYGAELV--EVDVPKPGPGEVLIKVLATSICGTDLHIYEWNEWAQSRIKPP 61 Query: 55 PGASNILGLEASGHVAELGPGCQGHWKIGDTA---------------------------M 87 I+G E +G V E+GPG +G ++GD Sbjct: 62 ----QIMGHEVAGEVVEIGPGVEG-IEVGDYVSVETHIVCGKCYACRRGQYHVCQNTKIF 116 Query: 88 ALLPGGGQAQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIH 147 + G A+Y VP + P+ + + A + E A + L G + +G VLI Sbjct: 117 GVDTDGVFAEYAVVPAQNIWKNPKSIP-PEYATLQEPLGNAVDTV-LAGPI-SGKSVLI- 172 Query: 148 AGLSGVGTAAIQLTRMAGAIP-LVTAGSQKKLQMAEKLGAAAGFNYKKEDFSEATLKFTK 206 G +G I + + +GA P +V+ S + ++A+K+GA N +ED + + T Sbjct: 173 TGAGPLGLLGIAVAKASGAYPVIVSEPSDFRRELAKKVGADYVINPFEEDVVKEVMDITD 232 Query: 207 GAGVNLILDCIGG-SYWEKNVNCLALDGRWVLYGLMGGG---DINGPLFSKLL 255 G GV++ L+ G E+ + + GR L GL G D N + K L Sbjct: 233 GNGVDVFLEFSGAPKALEQGLQAVTPAGRVSLLGLYPGKVTIDFNNLIIFKAL 285 >1H2B-A nrPDB Length = 359 Score = 62.4 bits (150), Expect = 3e-10, Method: Compositional matrix adjust. Identities = 83/358 (23%), Positives = 159/358 (44%), Gaps = 59/358 (16%) Query: 6 FDKPGGPENLYVKEVAKPS-PGEGEVLLKVAASALNRADLMQRQGQYDP--PPGASNILG 62 ++KP L +++V P G +V++++A + + DL QG + P LG Sbjct: 24 YNKP-----LRIEDVDYPRLEGRFDVIVRIAGAGVCHTDLHLVQGMWHELLQPKLPYTLG 78 Query: 63 LEASGHVAELGPGCQG---------HWKIGD-TAMALLPG----------------GGQA 96 E G++ E+ G +G H + D T +A G GG A Sbjct: 79 HENVGYIEEVAEGVEGLEKGDPVILHPAVTDGTCLACRAGEDMHCENLEFPGLNIDGGFA 138 Query: 97 QYVTVPEGLLMPIPEGLT---LTQAAAIPEAWLTAFQLLHLVG-NVQAGDYVLIHAGLSG 152 +++ ++ +P+ ++ L + A + +A +TA++ + + G YV I G+ G Sbjct: 139 EFMRTSHRSVIKLPKDISREKLVEMAPLADAGITAYRAVKKAARTLYPGAYVAI-VGVGG 197 Query: 153 VGTAAIQLTR-MAGAIPLVTAGSQKKLQMAEKLGAAAGFNYKKEDFSEATLKFTKGAGVN 211 +G A+QL + M A + ++KL++AE+LGA + ++ D + ++ T+G GVN Sbjct: 198 LGHIAVQLLKVMTPATVIALDVKEEKLKLAERLGADHVVDARR-DPVKQVMELTRGRGVN 256 Query: 212 LILDCIGG-SYWEKNVNCLALDGRWVLYGLMGGGDINGPLFSKLLFKRGSLITSLLRSRD 270 + +D +G + + L GR ++ G GG++ P + S + Sbjct: 257 VAMDFVGSQATVDYTPYLLGRMGRLIIVGY--GGELRFPTIRVI-------------SSE 301 Query: 271 NKYKQMLVNAFTEQILPHFSTEGPQRLLPVLDRIYPVTEIQEAHKYMEANKNIGKIVL 328 ++ LV + E L T Q + V I+ + EI + + +E + +G+ VL Sbjct: 302 VSFEGSLVGNYVE--LHELVTLALQGKVRVEVDIHKLDEINDVLERLEKGEVLGRAVL 357 >3S2F-A nrPDB Length = 340 Score = 61.2 bits (147), Expect = 6e-10, Method: Compositional matrix adjust. Identities = 70/280 (25%), Positives = 115/280 (41%), Gaps = 38/280 (13%) Query: 15 LYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNILGLEASGHVAELGP 74 L + EV P PG G+V +K+ AS + DL G + P I G E G+V+ +G Sbjct: 15 LTIDEVPVPQPGPGQVQVKIEASGVCHTDLHAADGDWPVKPTLPFIPGHEGVGYVSAVGS 74 Query: 75 G------------------------CQGHW-----KIGDTAMALLPGGGQAQYVTVPEGL 105 G C W K +T ++ GG +YV Sbjct: 75 GVSRVKEGDRVGVPWLYSACGYCEHCLQGWETLCEKQQNTGYSV--NGGYGEYVVADPNY 132 Query: 106 LMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAG 165 + +P+ + + A I A +T ++ L V + + G +V+I +G+ G+G A+Q R G Sbjct: 133 VGLLPDKVGFVEIAPILCAGVTVYKGLK-VTDTRPGQWVVI-SGIGGLGHVAVQYARAMG 190 Query: 166 AIPLVTAGSQKKLQMAEKLGAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIGGSYWEKN 225 KL +A +LGA N + D A L+ G +++ + + + Sbjct: 191 LRVAAVDIDDAKLNLARRLGAEVAVNARDTD-PAAWLQKEIGGAHGVLVTAVSPKAFSQA 249 Query: 226 VNCLALDGRWVLYGLMGGGDINGPLFSKLL---FKRGSLI 262 + + G L GL GD P+F +L RGS++ Sbjct: 250 IGMVRRGGTIALNGLP-PGDFGTPIFDVVLKGITIRGSIV 288 >2EER-A nrPDB Length = 347 Score = 60.8 bits (146), Expect = 7e-10, Method: Compositional matrix adjust. Identities = 83/367 (22%), Positives = 157/367 (42%), Gaps = 61/367 (16%) Query: 1 MLAVHFDKPGGPENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNI 60 M A+ + G P L ++++ P P +VL+K+ A+ + +D+ RQG++ ++ Sbjct: 1 MRAMRLVEIGKP--LKLEDIPIPKPKGSQVLIKIEAAGVCHSDVHMRQGRFGNLRIVEDL 58 Query: 61 -------LGLEASGHVAELGPGCQGH----------W---------KIGDTAMALLP--- 91 LG E +G + E+G G+ W +IG+ + P Sbjct: 59 GVKLPVTLGHEIAGRIEEVGDEVVGYSKGDLVAVNPWEGEGNCYYCRIGEEHLCDSPRWL 118 Query: 92 ----GGGQAQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIH 147 G A+YV VP + L+ +AA + + +T ++ + + V+I Sbjct: 119 GINYDGAYAEYVLVPHYKYLYKLRRLSAVEAAPLTCSGVTTYRAVRKASLDPSKTLVVIG 178 Query: 148 AGLSGVGTAAIQLTR-MAGAIPLVTAGSQKKLQMAEKLGAAAGFNYKKEDFSEATLKFTK 206 AG G+GT AIQ+ + ++GA + ++ L+ A++ GA N +D + T+ Sbjct: 179 AG-GGLGTMAIQIAKAVSGATIIGVDVREEALEAAKRAGADYVINASSQDPVSEIRRITQ 237 Query: 207 GAGVNLILDCIGGSYWEKNVN----CLALDGRWVLYGLMGGG-DINGPLFSKLLFKRGSL 261 G G + ++D + EK ++ LA G++V+ GL G + PL + Sbjct: 238 GKGADAVIDL---NNSEKTLSIYPYVLAKQGKYVMVGLFGADLKYHAPLIT---LNEVQF 291 Query: 262 ITSLLRSRDNKYKQMLVNAFTEQILPHFSTEGPQRLLPVLDRIYPVTEIQEAHKYMEANK 321 I SL+ ++ + L S ++ P++ + + E EA +E K Sbjct: 292 IGSLVGNQSD-------------FLGIMSLAEAGKVKPMVTKTMKLEEANEAIDNLENFK 338 Query: 322 NIGKIVL 328 +G+ VL Sbjct: 339 AVGRQVL 345 >4EJ6-A nrPDB Length = 370 Score = 60.1 bits (144), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 85/305 (27%), Positives = 127/305 (41%), Gaps = 46/305 (15%) Query: 1 MLAVHFDKPGGPENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNI 60 M AV + G N+ V+ V P PG ++L+KV A + D G++ P + Sbjct: 24 MKAVRLESVG---NISVRNVGIPEPGPDDLLVKVEACGICGTDRHLLHGEFPSTPPVT-- 78 Query: 61 LGLEASGHVAELG-----------------------PGCQ-GHWKIGDT--AMALLPGGG 94 LG E G V E G P CQ G + A+ + GG Sbjct: 79 LGHEFCGIVVEAGSAVRDIAPGARITGDPNISCGRCPQCQAGRVNLCRNLRAIGIHRDGG 138 Query: 95 QAQYVTVPEGLLMPIPEGLTLTQA-AAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGV 153 A+YV VP IP LTL A E + L G ++AG V I G + Sbjct: 139 FAEYVLVPRKQAFEIP--LTLDPVHGAFCEPLACCLHGVDLSG-IKAGSTVAILGG-GVI 194 Query: 154 GTAAIQLTRMAGAIPLVTAGSQ-KKLQMAEKLGAAAGFNYKKEDFSEAT---LKFTKGAG 209 G +QL R+AGA ++ + Q K ++AE++GA A + D EA + G G Sbjct: 195 GLLTVQLARLAGATTVILSTRQATKRRLAEEVGATATVDPSAGDVVEAIAGPVGLVPG-G 253 Query: 210 VNLILDCIGGSYWEKNVNCLA-LDGRWVLYGLMGGGDINGPLFSKLLFKR----GSLITS 264 V+++++C G + K LA G V+ G++ G+ +LF+ GS I Sbjct: 254 VDVVIECAGVAETVKQSTRLAKAGGTVVILGVLPQGEKVEIEPFDILFRELRVLGSFINP 313 Query: 265 LLRSR 269 + R Sbjct: 314 FVHRR 318 >4Y1B-A nrPDB Length = 425 Score = 58.5 bits (140), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 69/261 (26%), Positives = 106/261 (40%), Gaps = 46/261 (17%) Query: 7 DKPGGPENLYVKEVAKPSP-GEGEVLLKVAASALNRADLM-------------QRQGQY- 51 ++ G P + + EV P G G+VL+KV A+ +N ++ Q+QG Sbjct: 49 ERYGRPVDAFRTEVVDVPPVGPGQVLVKVMAAGVNYNNVWAALGEPLDVIAARQKQGATE 108 Query: 52 DPPPGASNILGL-EASGHVAELGPG-------CQGHWKIGDTAMALLP------------ 91 D G S++ G+ A G L PG C+ D + P Sbjct: 109 DFHIGGSDLSGIVWAVGDGVRLKPGAEVVVLACRWDESAQDIRLGADPVTSSTQRVWGYE 168 Query: 92 --GGGQAQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVG----NVQAGDYVL 145 G AQ+ V E + P P+ L+ A+ TA++ L G V+ GD VL Sbjct: 169 ENYGSFAQFAVVDEYMCHPKPQRLSWAAASCYMATAATAYR--QLFGWEPHTVRPGDPVL 226 Query: 146 IHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQMAEKLGAAAGFNYKKEDFSEATLKFT 205 I G G+G+ AIQL R G IP+ S+++ + +LGA + ++ D T Sbjct: 227 IWGGAGGLGSIAIQLVRHVGGIPVAVVSSEERGEFCMRLGAKGWIDRREFDHWGRLPDTT 286 Query: 206 KGAGVNLILD---CIGGSYWE 223 + LD G +WE Sbjct: 287 DEEAMKQWLDGARAFGRRFWE 307 >2J3K-A nrPDB Length = 345 Score = 58.2 bits (139), Expect = 5e-09, Method: Compositional matrix adjust. Identities = 53/208 (25%), Positives = 99/208 (47%), Gaps = 13/208 (6%) Query: 126 LTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQMAE-KL 184 +TA+ + V + + G+ V + A VG QL +M G + +AGS++K+ + + K Sbjct: 141 MTAYAGFYEVCSPKEGETVYVSAASGAVGQLVGQLAKMMGCYVVGSAGSKEKVDLLKTKF 200 Query: 185 GAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIGGSYWEKNVNCLALDGRWVLYGLMGGG 244 G FNYK+E A LK G+++ + +GG + + + + GR + G++ Sbjct: 201 GFDDAFNYKEESDLTAALKRCFPNGIDIYFENVGGKMLDAVLVNMNMHGRIAVCGMISQY 260 Query: 245 DINGPL----FSKLLFKRGSLITSLLRSRDNKYKQMLVNAFTEQILPHFSTEGPQRLLPV 300 ++ S +++KR + ++ +KY + F E +LPH EG ++ V Sbjct: 261 NLENQEGVHNLSNIIYKRNRIQGFVVSDFYDKYSK-----FLEFVLPHIR-EG--KITYV 312 Query: 301 LDRIYPVTEIQEAHKYMEANKNIGKIVL 328 D + + EA + KN+GK V+ Sbjct: 313 EDVADGLEKAPEALVGLFHGKNVGKQVV 340 >5YAT-A nrPDB Length = 350 Score = 58.2 bits (139), Expect = 6e-09, Method: Compositional matrix adjust. Identities = 87/359 (24%), Positives = 147/359 (40%), Gaps = 48/359 (13%) Query: 3 AVHFDKPGGPENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNILG 62 AV F+ GGP L K++ P P E+L+ V S + DL +G + + G Sbjct: 11 AVIFETNGGP--LEYKDIPVPKPKSNELLINVKYSGVCHTDLHAWKGDWPLDNKLPLVGG 68 Query: 63 LEASGHVAELGPGCQGHWKIGD------------------------TAMALLPG----GG 94 E +G V G G W+IGD A A L G G Sbjct: 69 HEGAGVVVAYGENVTG-WEIGDYAGIKWLNGSCLNCEYCIQGAESSCAKADLSGFTHDGS 127 Query: 95 QAQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVG 154 QY T IP+ L + A I A +T ++ L +++ G +V I G+G Sbjct: 128 FQQYATADATQAARIPKEADLAEVAPILCAGITVYKALK-TADLRIGQWVAISGAGGGLG 186 Query: 155 TAAIQLTRMAGAIPLVTAGSQKKLQMAEKLGAAAGFNY-KKEDFSEATLKFTKGAGVNLI 213 + A+Q + G L G K + + LGA ++ K +D K T G +I Sbjct: 187 SLAVQYAKALGLRVLGIDGGADKGEFVKSLGAEVFVDFTKTKDVVAEVQKLTNGGPHGVI 246 Query: 214 LDCIGGSYWEKNVNCLALDGRWVLYGLMGGGDINGPLFSKLLFKRGSLITSLLRSRDNKY 273 + ++V + G+ VL GL G +N +F +L K + S + +R++ Sbjct: 247 NVSVSPHAINQSVQYVRTLGKVVLVGLPSGAVVNSDVFWHVL-KSIEIKGSYVGNREDSA 305 Query: 274 KQMLVNAFTEQILPHFSTEGPQRLLPVLDRIYPVTEIQEAHKYMEANKNIGKIVLELPQ 332 + ++ FT ++ P+ +I ++E+ + ++ MEA IG+ V++ + Sbjct: 306 EA--IDLFTRGLVK----------API--KIIGLSELAKVYEQMEAGAIIGRYVVDTSK 350 >2VCY-A nrPDB Length = 344 Score = 57.0 bits (136), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 64/235 (27%), Positives = 104/235 (44%), Gaps = 7/235 (2%) Query: 28 GEVLLKVAASALNRADLMQRQGQYDPPPGASNILGLEASGHVAELGPGCQGHWKIGDTAM 87 +V +K+ A+ +N +D+ QG Y P + G E V +G G K GD + Sbjct: 42 SDVRVKMLAAPINPSDINMIQGNYGLLPELPAVGGNEGVAQVVAVGSNVTG-LKPGDWVI 100 Query: 88 ALLPGGGQAQYVTV-PEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLI 146 G G + V E L+ +P + L AA + TA+++L +Q GD V+ Sbjct: 101 PANAGLGTWRTEAVFSEEALIQVPSDIPLQSAATLGVNPCTAYRMLMDFEQLQPGDSVIQ 160 Query: 147 HAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQ-MAEKLGA-AAGFNYKKEDFSEATLK- 203 +A SGVG A IQ+ G + + +Q ++++L + A +E+ +K Sbjct: 161 NASNSGVGQAVIQIAAALGLRTINVVRDRPDIQKLSDRLKSLGAEHVITEEELRRPEMKN 220 Query: 204 -FTKGAGVNLILDCIGGSYWEKNVNCLALDGRWVLYGLMGGGDINGPLFSKLLFK 257 F L L+C+GG + + LA G V YG M + + S L+FK Sbjct: 221 FFKDMPQPRLALNCVGGKSSTELLRQLARGGTMVTYGGMAKQPVVASV-SLLIFK 274 >3HZZ-A nrPDB Length = 467 Score = 56.2 bits (134), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 63/231 (27%), Positives = 97/231 (41%), Gaps = 47/231 (20%) Query: 13 ENLYVKEVAKPSPGEGEVLLKVAASALNRADL-------------MQRQGQYDPPPGASN 59 +++++ EV P G GE L+ V AS++N + ++R G+ P + Sbjct: 74 KSIHLDEVPVPELGPGEALVAVMASSVNYNSVWTSIFEPVSTFAFLERYGKLSPLTKRHD 133 Query: 60 ----ILGLEASGHVAELGPGCQGHWKIGDTAMA-----------------LLPG------ 92 I+G + +G V GPG W+ GD +A L P Sbjct: 134 LPYHIIGSDLAGVVLRTGPGVNA-WQPGDEVVAHCLSVELESPDGHDDTMLDPEQRIWGF 192 Query: 93 ----GGQAQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAF-QLLHLVGN-VQAGDYVLI 146 GG A+ V LMP P+ LT +AAA TA+ QL+ G ++ GD VLI Sbjct: 193 ETNFGGLAEIALVKTNQLMPKPKHLTWEEAAAPGLVNSTAYRQLVSRNGAAMKQGDNVLI 252 Query: 147 HAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQMAEKLGAAAGFNYKKEDF 197 G+G+ A Q GA P+ S +K ++ +GA A + E + Sbjct: 253 WGASGGLGSYATQFALAGGANPICVVSSPQKAEICRSMGAEAIIDRNAEGY 303 >3GFB-A nrPDB Length = 350 Score = 55.8 bits (133), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 73/258 (28%), Positives = 112/258 (43%), Gaps = 44/258 (17%) Query: 19 EVAKPSPGEGEVLLKVAASALNRADLM------QRQGQYDPPPGASNILGLEASGHVAEL 72 EV P PG GEVL+KV A+++ DL Q + PP I+G E +G V E+ Sbjct: 21 EVDVPKPGPGEVLIKVLATSICGTDLHIYEWNEWAQSRIKPP----QIMGHEVAGEVVEV 76 Query: 73 GPGCQGHWKIGD---TAMALLPG------------------------GGQAQYVTVPEGL 105 GPG + ++GD ++ G G A Y VP Sbjct: 77 GPGVE-DLQVGDYISVETHIVCGKCYACKHNRYHVCQNTKIFGVDMDGVFAHYAIVPAKN 135 Query: 106 LMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAG 165 P+ + + AA+ E A + L G + AG LI G +G I + + +G Sbjct: 136 AWKNPKDMP-PEYAALQEPLGNAVDTV-LAGPI-AGRSTLI-TGAGPLGLLGIAVAKASG 191 Query: 166 AIP-LVTAGSQKKLQMAEKLGAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIGG-SYWE 223 A P +V+ S+ + ++A+K+GA N +ED + + T GAGV + L+ G E Sbjct: 192 AYPVIVSEPSEFRRKLAKKVGADYVVNPFEEDPVKFVMDITDGAGVEVFLEFSGAPKALE 251 Query: 224 KNVNCLALDGRWVLYGLM 241 + + + GR L GL Sbjct: 252 QGLKAVTPGGRVSLLGLF 269 >6FG0-A nrPDB Length = 352 Score = 55.1 bits (131), Expect = 5e-08, Method: Compositional matrix adjust. Identities = 74/281 (26%), Positives = 113/281 (40%), Gaps = 45/281 (16%) Query: 1 MLAVHFDKPGGPENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQ---GQYDPPPGA 57 M AV + + G V ++ P+PG GE+LLKV A+ L +D+ QY G Sbjct: 1 MKAVQYTEIG--SEPVVVDIPTPTPGPGEILLKVTAAGLCHSDITVMDMPAAQY--AGGL 56 Query: 58 SNILGLEASGHVAELGPGCQGHWKIGDTAMALLPGG---------GQAQYVT-------V 101 LG E G VAELG G G + +GD P G G+ Y T Sbjct: 57 PLTLGHEGVGTVAELGEGVTG-FGVGDAVAVYGPWGCGACHACARGRENYCTRAADLGIT 115 Query: 102 PEGL-----------------LMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYV 144 P G L+PI + L AA + +A LT + + V + Sbjct: 116 PPGYGSPGSMAEYMIVDSARHLVPIGD-LDPVAAAPLTDAGLTPYHAISRVLPLLGPGST 174 Query: 145 LIHAGLSGVGTAAIQLTRMAGAIPLVTAG-SQKKLQMAEKLGAAAGFNYKKEDFSEATLK 203 + G+ G+G IQ+ R A ++ +L +A ++GA A ++A + Sbjct: 175 AVVIGVGGLGHVGIQILRAVSAARVIAVDLDDDRLALAREVGADAAVK-SGAGAADAIRE 233 Query: 204 FTKGAGVNLILDCIGG-SYWEKNVNCLALDGRWVLYGLMGG 243 T G G + D +G S + +A+DG + G+ G Sbjct: 234 LTGGQGATAVFDFVGAQSTIDTAQQVVAVDGHISVVGIHAG 274 >1V3V-A nrPDB Length = 333 Score = 53.1 bits (126), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 39/120 (32%), Positives = 59/120 (49%), Gaps = 1/120 (0%) Query: 103 EGLLMPIPEGLTLTQA-AAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLT 161 E LL P+ L L+ A I LTA+ L V V+ G+ VL+ A VG+ Q+ Sbjct: 107 EKLLTEWPDKLPLSLALGTIGMPGLTAYFGLLEVCGVKGGETVLVSAAAGAVGSVVGQIA 166 Query: 162 RMAGAIPLVTAGSQKKLQMAEKLGAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIGGSY 221 ++ G + AGS +K+ +++G A FNYK + E LK G + D +GG + Sbjct: 167 KLKGCKVVGAAGSDEKIAYLKQIGFDAAFNYKTVNSLEEALKKASPDGYDCYFDNVGGEF 226 >6N7L-A nrPDB Length = 353 Score = 52.8 bits (125), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 82/344 (23%), Positives = 135/344 (39%), Gaps = 45/344 (13%) Query: 13 ENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNILGLEASGHVAEL 72 E L ++EV PG EVL+KV A + DL G + P I G E G V Sbjct: 24 EPLKIQEVPVREPGRYEVLVKVMACGVCHTDLHAVDGDWPAKPKMPLIPGHEGVGIVVAC 83 Query: 73 GP-------------------GCQGHWKIGDTAMA-------LLPGGGQAQYVTVPEGLL 106 GP GC + G + GG A+YV + Sbjct: 84 GPDAMVKEGDAVGVPWLYSACGCCDYCITGWETLCEAQQNGGYSVDGGFAEYVIADSRYV 143 Query: 107 MPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGA 166 + + + A I A +T ++ L + G++V I +G+ G+G A+Q + G Sbjct: 144 GHLKSNVNFLEIAPILCAGVTVYKGLKET-ETKPGEWVAI-SGIGGLGHVAVQYAKAMGM 201 Query: 167 IPLVTAGSQKKLQMAEKLGAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIGGSYWEKNV 226 + KL++A+KLGA N K D K G LI + +++ + Sbjct: 202 HVAAIDVADDKLELAKKLGADLTVNAKTTDPGTYLHKEVGGMHGALIT-AVSPIAFKQGI 260 Query: 227 NCLALDGRWVLYGLMGGGDINGPLFSKLLFKRGSLITSLLRSRDNKYKQMLVNAFTEQIL 286 + L G L GL G P+F +L KR ++ S++ +R + + + Sbjct: 261 DVLRRKGTIALNGLP-PGSFELPIFETVL-KRITVRGSIVGTRKDLQEAL---------- 308 Query: 287 PHFSTEGPQRLLPVLDRIYPVTEIQEAHKYMEANKNIGKIVLEL 330 F+ EG L+ + +I + M+ + G+IVL++ Sbjct: 309 -DFANEG---LVKATVTSAKLEDINDVFDKMKKGQIDGRIVLDI 348 >5VM2-A nrPDB Length = 347 Score = 52.4 bits (124), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 60/249 (24%), Positives = 102/249 (40%), Gaps = 39/249 (15%) Query: 23 PSPGEGEVLLKVAASALNRADLMQ-RQGQYDPPPGASNILGL--EASGHVAELG------ 73 P P E EVL+KV + +D+ G + PP + +GL E +G V +G Sbjct: 22 PVPKEDEVLIKVEYVGICGSDVHGFESGPFIPPKDPNQEIGLGHECAGTVVAVGSRVRKF 81 Query: 74 ---------PG--------C-QGHWKIGDTA--MALLPG--GGQAQYVTVPEGLLMPIPE 111 PG C +G + I MA P G Y+ PE +P+ Sbjct: 82 KPGDRVNIEPGVPCGHCRYCLEGKYNICPDVDFMATQPNYRGALTHYLCHPESFTYKLPD 141 Query: 112 GLTLTQAAAIPEAWLTAFQLLH--LVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPL 169 + + + A + +H ++ +V+ G ++I G +G +Q + GA + Sbjct: 142 NMDTMEGTLVEPAAVG----MHAAMLADVKPGKKIII-LGAGCIGLMTLQACKCLGATEI 196 Query: 170 VTAGS-QKKLQMAEKLGAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIGGSYWEKNVNC 228 +K+L MAE+LGA N KED +FT+ G +++ + G + K Sbjct: 197 AVVDVLEKRLAMAEQLGATVVINGAKEDTIARCQQFTEDMGADIVFETAGSAVTVKQAPY 256 Query: 229 LALDGRWVL 237 L + G ++ Sbjct: 257 LVMRGGKIM 265 >2Y05-A nrPDB Length = 328 Score = 52.0 bits (123), Expect = 4e-07, Method: Compositional matrix adjust. Identities = 42/139 (30%), Positives = 67/139 (48%), Gaps = 3/139 (2%) Query: 103 EGLLMPIPEGLTLTQA-AAIPEAWLTA-FQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQL 160 E LL P+ + L+ A + LTA F LL + G V+ G+ V+++A VG+ Q+ Sbjct: 102 EKLLTEWPDTIPLSLALGTVGMPGLTAYFGLLEICG-VKGGETVMVNAAAGAVGSVVGQI 160 Query: 161 TRMAGAIPLVTAGSQKKLQMAEKLGAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIGGS 220 ++ G + GS +K+ +KLG FNYK + E TLK G + D +GG Sbjct: 161 AKLKGCKVVGAVGSDEKVAYLQKLGFDVVFNYKTVESLEETLKKASPDGYDCYFDNVGGE 220 Query: 221 YWEKNVNCLALDGRWVLYG 239 + + + GR + G Sbjct: 221 FSNTVIGQMKKFGRIAICG 239 >4EEZ-A nrPDB Length = 348 Score = 50.4 bits (119), Expect = 9e-07, Method: Compositional matrix adjust. Identities = 64/243 (26%), Positives = 99/243 (40%), Gaps = 36/243 (14%) Query: 3 AVHFDKPGGPENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNILG 62 AV P G +L KE+ P E LL + + DL G + G +LG Sbjct: 4 AVVRHNPDGYADLVEKELRAIKPNEA--LLDMEYCGVCHTDLHVAAGDFGNKAG--TVLG 59 Query: 63 LEASGHVAELGP------------------GCQGHWKIGDTAMALLP----------GGG 94 E G V E+G GC GH + + GG Sbjct: 60 HEGIGIVKEIGADVSSLQVGDRVSVAWFFEGC-GHCEYCVSGNETFCREVKNAGYSVDGG 118 Query: 95 QAQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVG 154 A+ V + +P+GL +A++I A +T ++ + + G V+ GD+ +I G G+G Sbjct: 119 MAEEAIVVADYAVKVPDGLDPIEASSITCAGVTTYKAIKVSG-VKPGDWQVIF-GAGGLG 176 Query: 155 TAAIQLTR-MAGAIPLVTAGSQKKLQMAEKLGAAAGFNYKKEDFSEATLKFTKGAGVNLI 213 AIQ + + GA + +Q KL +A+K+GA N + + K T G GV Sbjct: 177 NLAIQYAKNVFGAKVIAVDINQDKLNLAKKIGADVTINSGDVNPVDEIKKITGGLGVQSA 236 Query: 214 LDC 216 + C Sbjct: 237 IVC 239 >1R37-A nrPDB Length = 347 Score = 49.7 bits (117), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 66/281 (23%), Positives = 124/281 (44%), Gaps = 44/281 (15%) Query: 1 MLAVHFDKPGGPENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNI 60 M AV + G P L ++E+ P P +VL+KV A+ + +D+ RQG++ ++ Sbjct: 1 MRAVRLVEIGKP--LSLQEIGVPKPKGPQVLIKVEAAGVCHSDVHMRQGRFGNLRIVEDL 58 Query: 61 -------LGLEASGHVAELGPGCQGH----------W---------KIGDTAMALLP--- 91 LG E +G + E+G G+ W +IG+ + P Sbjct: 59 GVKLPVTLGHEIAGKIEEVGDEVVGYSKGDLVAVNPWQGEGNCYYCRIGEEHLCDSPRWL 118 Query: 92 ----GGGQAQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIH 147 G A+YV VP M L +AA + + +T ++ + ++ +L+ Sbjct: 119 GINFDGAYAEYVIVPHYKYMYKLRRLNAVEAAPLTCSGITTYRAVRK-ASLDPTKTLLVV 177 Query: 148 AGLSGVGTAAIQLTR-MAGAIPLVTAGSQKKLQMAEKLGAAAGFNYKKEDFSEATLKFTK 206 G+GT A+Q+ + ++GA + ++ ++ A++ GA N +D + T+ Sbjct: 178 GAGGGLGTMAVQIAKAVSGATIIGVDVREEAVEAAKRAGADYVINASMQDPLAEIRRITE 237 Query: 207 GAGVNLILDCIGGSYWEKNVNC----LALDGRWVLYGLMGG 243 GV+ ++D + EK ++ LA G++V+ GL G Sbjct: 238 SKGVDAVIDL---NNSEKTLSVYPKALAKQGKYVMVGLFGA 275 >3FPC-A nrPDB Length = 352 Score = 48.5 bits (114), Expect = 4e-06, Method: Compositional matrix adjust. Identities = 63/231 (27%), Positives = 99/231 (42%), Gaps = 41/231 (17%) Query: 19 EVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASN--ILGLEASGHVAELGPGC 76 E KP+PG + +++ A A +D+ ++ G + ILG EA G V E+G Sbjct: 16 EKEKPAPGPFDAIVRPLAVAPCTSDI---HTVFEGAIGERHNMILGHEAVGEVVEVGSEV 72 Query: 77 QGHWKIGDTAM--ALLP---------------GGGQA--QYVTVPEGL------------ 105 + +K GD + A+ P GG A ++ V +G+ Sbjct: 73 K-DFKPGDRVVVPAITPDWRTSEVQRGYHQHSGGMLAGWKFSNVKDGVFGEFFHVNDADM 131 Query: 106 -LMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMA 164 L +P+ + L A IP+ T F L N++ GD V + G+ VG ++ Sbjct: 132 NLAHLPKEIPLEAAVMIPDMMTTGFHGAEL-ANIKLGDTVCV-IGIGPVGLMSVAGANHL 189 Query: 165 GAIPLVTAGSQKKL-QMAEKLGAAAGFNYKKEDFSEATLKFTKGAGVNLIL 214 GA + GS+K +A + GA NYK D E LK T G GV+ ++ Sbjct: 190 GAGRIFAVGSRKHCCDIALEYGATDIINYKNGDIVEQILKATDGKGVDKVV 240 >4GKV-A nrPDB Length = 336 Score = 48.1 bits (113), Expect = 5e-06, Method: Compositional matrix adjust. Identities = 75/331 (22%), Positives = 137/331 (41%), Gaps = 49/331 (14%) Query: 28 GEVLLKVAASALNRADLMQRQGQYDPPPGASNILGLEASGHVAELGPGCQ---------- 77 GE LLK+ + DL + G + G ILG E G VAE+GPG Sbjct: 25 GEALLKMECCGVCHTDLHVKNGDFGDKTGV--ILGHEGIGVVAEVGPGVTSLKPGDRASV 82 Query: 78 -------GHWKIGDTAMALLP----------GGGQAQYVTVPEGLLMPIPEGLTLTQAAA 120 GH + ++ L GG A+ V + +P+GL A++ Sbjct: 83 AWFYEGCGHCEYCNSGNETLCRSVKNAGYSVDGGMAEECIVVADYAVKVPDGLDSAAASS 142 Query: 121 IPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQM 180 I A +T ++ + L ++ G ++ I+ A + A + + ++L++ Sbjct: 143 ITCAGVTTYKAVKL-SKIRPGQWIAIYGLGGLGNLALQYAKNVFNAKVIAIDVNDEQLKL 201 Query: 181 AEKLGAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIGGSYWEKNVNCLALDGRWVLYGL 240 A ++GA N ED ++ + T GA ++ + + + V+ + GR V GL Sbjct: 202 ATEMGADLAINSHTEDAAKIVQEKTGGAHAAVVTA-VAKAAFNSAVDAVRAGGRVVAVGL 260 Query: 241 -MGGGDINGPLFSKLLFKRGSLITSLLRSRDNKYKQMLVNAFTEQILPHFSTEGPQRLLP 299 ++ P +L+ ++ SL+ +R Q L AF F+ EG +++P Sbjct: 261 PPESMSLDIP---RLVLDGIEVVGSLVGTR-----QDLTEAF------QFAAEG--KVVP 304 Query: 300 VLDRIYPVTEIQEAHKYMEANKNIGKIVLEL 330 + + P+ +I ME K G++V++ Sbjct: 305 KV-ALRPLADINTIFTEMEEGKIRGRMVIDF 334 >3FSR-A nrPDB Length = 352 Score = 47.4 bits (111), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 63/237 (26%), Positives = 101/237 (42%), Gaps = 41/237 (17%) Query: 19 EVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASN--ILGLEASGHVAELGPGC 76 E KP+PG + +++ A A +D+ ++ G + ILG EA G V E+G Sbjct: 16 EKEKPAPGPFDAIVRPLAVAPCTSDI---HTVFEGAIGERHNMILGHEAVGEVVEVGSEV 72 Query: 77 QGHWKIGDTAM--ALLP---------------GGGQA--QYVTVPEGL------------ 105 + +K GD + A+ P GG A ++ V +G+ Sbjct: 73 K-DFKPGDRVVVPAITPDWRTSEVQRGYHQHSGGMLAGWKFSNVKDGVFGEFFHVNDADM 131 Query: 106 -LMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMA 164 L +P+ + L A IP+ T F L ++Q G V++ G+ VG I ++ Sbjct: 132 NLAHLPKEIPLEAAVMIPDMMTTGFHGAEL-ADIQMGSSVVV-IGIGAVGLMGIAGAKLR 189 Query: 165 GAIPLVTAGSQKKLQMAEKL-GAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIGGS 220 GA ++ GS+ A K GA NYK + +K T G GV+ ++ GGS Sbjct: 190 GAGRIIGVGSRPICVEAAKFYGATDILNYKNGHIVDQVMKLTNGKGVDRVIMAGGGS 246 >3IP1-A nrPDB Length = 404 Score = 46.6 bits (109), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 29/84 (34%), Positives = 48/84 (57%), Gaps = 2/84 (2%) Query: 136 GNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLV-TAGSQKKLQMAEKLGAAAGFNYKK 194 G ++ GD V+I G +G AA+ + + AGA ++ + S+ + +A++LGA + K Sbjct: 209 GGIRPGDNVVILGG-GPIGLAAVAILKHAGASKVILSEPSEVRRNLAKELGADHVIDPTK 267 Query: 195 EDFSEATLKFTKGAGVNLILDCIG 218 E+F EA L +T G G L L+ G Sbjct: 268 ENFVEAVLDYTNGLGAKLFLEATG 291 >2DQ4-A nrPDB Length = 343 Score = 45.1 bits (105), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 66/239 (27%), Positives = 101/239 (42%), Gaps = 42/239 (17%) Query: 13 ENLYVKEVAKPSPGEGEVLLKVAASALNRADL------MQRQGQYDPPPGASNILGLEAS 66 E L + + P PG GE+L++V A+++ DL +G+ PP + G E S Sbjct: 11 EGLTLVDRPVPEPGPGEILVRVEAASICGTDLHIWKWDAWARGRIRPP----LVTGHEFS 66 Query: 67 GHVAELGPG-----------------CQG---------HWKIGDTAMALLPGGGQAQYVT 100 G V +GPG C H + + + GG A+YV Sbjct: 67 GVVEAVGPGVRRPQVGDHVSLESHIVCHACPACRTGNYHVCLNTQILGVDRDGGFAEYVV 126 Query: 101 VPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQL 160 VP P+ L + AAI E + A ++ G+ +G VLI G +G A + Sbjct: 127 VPAENAWVNPKDLPF-EVAAILEPFGNAVHTVY-AGSGVSGKSVLI-TGAGPIGLMAAMV 183 Query: 161 TRMAGAIP-LVTAGSQKKLQMAEKLGAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIG 218 R +GA P LV+ + +L A A N +ED E + T G+GV ++L+ G Sbjct: 184 VRASGAGPILVSDPNPYRLAFARPY-ADRLVNPLEEDLLEVVRRVT-GSGVEVLLEFSG 240 >1MC5-A nrPDB Length = 374 Score = 44.7 bits (104), Expect = 5e-05, Method: Compositional matrix adjust. Identities = 63/259 (24%), Positives = 99/259 (38%), Gaps = 63/259 (24%) Query: 15 LYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNILGLEASGHVAELGP 74 L ++E+ P EV +K+ A+A+ D G DP ILG E +G V +G Sbjct: 20 LSIEEIEVAPPKAHEVRIKIIATAVCHTDAYTLSGA-DPEGCFPVILGHEGAGIVESVGE 78 Query: 75 GCQGHWKIGDTAMAL-LPGGGQAQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQ--- 130 G K GDT + L +P G+ ++ P+ L + + +TQ + + F Sbjct: 79 GVT-KLKAGDTVIPLYIPQCGECKFCLNPKTNLC---QKIRVTQGKGLMPDGTSRFTCKG 134 Query: 131 --LLHLVGNVQAGDYVLIHA---------------------------------------- 148 +LH +G +Y ++ Sbjct: 135 KTILHYMGTSTFSEYTVVADISVAKIDPLAPLDKVCLLGCGISTGYGAAVNTAKLEPGSV 194 Query: 149 ----GLSGVGTAAIQLTRMAGAIPLVTAGSQK-KLQMAEKLGAAAGFNYKKEDFS----E 199 GL GVG A I ++AGA ++ K K A++ GA N +DFS E Sbjct: 195 CAVFGLGGVGLAVIMGCKVAGASRIIGVDINKDKFARAKEFGATECIN--PQDFSKPIQE 252 Query: 200 ATLKFTKGAGVNLILDCIG 218 ++ T G GV+ +CIG Sbjct: 253 VLIEMTDG-GVDYSFECIG 270 >1KEV-A nrPDB Length = 351 Score = 42.7 bits (99), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 36/128 (28%), Positives = 58/128 (45%), Gaps = 3/128 (2%) Query: 94 GQAQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGV 153 G+ +V + L +P+ + L A I + T F L ++Q G V++ G+ V Sbjct: 121 GEYFHVNDADMNLAILPKDMPLENAVMITDMMTTGFHGAEL-ADIQMGSSVVV-IGIGAV 178 Query: 154 GTAAIQLTRMAGAIPLVTAGSQKKLQMAEKL-GAAAGFNYKKEDFSEATLKFTKGAGVNL 212 G I ++ GA ++ GS+ A K GA NYK + +K T G GV+ Sbjct: 179 GLMGIAGAKLRGAGRIIGVGSRPICVEAAKFYGATDILNYKNGHIVDQVMKLTNGKGVDR 238 Query: 213 ILDCIGGS 220 ++ GGS Sbjct: 239 VIMAGGGS 246 >5LB9-A nrPDB Length = 385 Score = 41.2 bits (95), Expect = 6e-04, Method: Compositional matrix adjust. Identities = 69/306 (22%), Positives = 117/306 (38%), Gaps = 42/306 (13%) Query: 3 AVHFDKPGGPENLYVK---EVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASN 59 AV + + G P+++ E+ + EV++K S +N +D+ Q QG Y P + Sbjct: 27 AVLYTQHGEPKDVLFTQSFEIDDDNLAPNEVIVKTLGSPVNPSDINQIQGVYPSKPAKTT 86 Query: 60 ILG----------------LEASGHVAELGPG---CQGHWKIGDTAMALLPGGGQAQYVT 100 G ++ +V+ L G H G L G ++ Sbjct: 87 GFGTTEPAAPCGNEGLFEVIKVGSNVSSLEAGDWVIPSHVNFGTWRTHAL--GNDDDFIK 144 Query: 101 VP---EGLLMPIPEGLTLTQAAAIPEAWLTAFQLL-HLVGNVQAGDYVLIHAGLSGVGTA 156 +P + P GLT+ Q A I L A+ +L H V D+ + + G S VG Sbjct: 145 LPNPAQSKANGKPNGLTINQGATISVNPLVAYLMLTHYVKLTPGKDWFIQNGGTSAVGKY 204 Query: 157 AIQLTRMAGAIPLVTAGSQKKLQMA----EKLGAAAGFNYKK---EDFSEATLKFTKGAG 209 A Q+ ++ + + L ++LGA + +F ++ K +G Sbjct: 205 ASQIGKLLNFNSISVIRDRPNLDEVVASLKELGATQVITEDQNNSREFGPTIKEWIKQSG 264 Query: 210 --VNLILDCIGGSYWEKNVNCLALDGRWVLYGLMGGGDINGPLFSKLLFKR----GSLIT 263 L L+C+GG L +G + YG M + P S +FK G +T Sbjct: 265 GEAKLALNCVGGKSSTGIARKLNNNGLMLTYGGMSFQPVTIPT-SLYIFKNFTSAGFWVT 323 Query: 264 SLLRSR 269 LL++ Sbjct: 324 ELLKNN 329 >2OUI-A nrPDB Length = 360 Score = 40.4 bits (93), Expect = 0.001, Method: Compositional matrix adjust. Identities = 37/141 (26%), Positives = 59/141 (41%), Gaps = 6/141 (4%) Query: 75 GCQGHWKIGDTAMALLPGGGQAQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHL 134 G G WK + + + +V + L +P + A + + T F L Sbjct: 105 GMLGGWKFSNFKDGVFS---EVFHVNEADANLALLPRDIKPEDAVMLSDMVTTGFHGAEL 161 Query: 135 VGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKL-QMAEKLGAAAGFNYK 193 N++ GD V + G+ VG ++ GA + GS+K +A + GA NYK Sbjct: 162 A-NIKLGDTVCV-IGIGPVGLMSVAGANHLGAGRIFAVGSRKHCCDIALEYGATDIINYK 219 Query: 194 KEDFSEATLKFTKGAGVNLIL 214 D E LK T G GV+ ++ Sbjct: 220 NGDIVEQILKATDGKGVDKVV 240 >2H6E-A nrPDB Length = 344 Score = 40.0 bits (92), Expect = 0.001, Method: Compositional matrix adjust. Identities = 64/270 (23%), Positives = 111/270 (41%), Gaps = 51/270 (18%) Query: 13 ENLYVKEVAKPSPGEGEVLLKVAASALNRADLM------QRQGQYDPPPGASNILGLEAS 66 E L +++V P P EVL+++ + + R DL +QG P ILG E + Sbjct: 14 EPLSIEDVNIPEPQGEEVLIRIGGAGVCRTDLRVWKGVEAKQGFRLPI-----ILGHENA 68 Query: 67 GHVAELGPGCQGHWKIGDTAMA-----------------------LLPG----GGQAQYV 99 G + E+G K GD + ++PG GG ++Y+ Sbjct: 69 GTIVEVGE--LAKVKKGDNVVVYATWGDLTCRYCREGKFNICKNQIIPGQTTNGGFSEYM 126 Query: 100 TVPEGLLMPIPEGLTLTQAAAIPEAWLTAF----QLLHLVGNVQAGDYVLIHAGLSGVGT 155 V + L+ +AA + +A T+ Q L + + + V+I G+ G+ Sbjct: 127 LVKSSRWLVKLNSLSPVEAAPLADAGTTSMGAIRQALPFIS--KFAEPVVIVNGIGGLAV 184 Query: 156 AAIQLTR--MAGAIPLVTAGSQKKLQMAEKLGAAAGFNYKKEDFSEATLKFTKGAGVNLI 213 IQ+ + M + + S+K A +LG A + + +D K T G G ++ Sbjct: 185 YTIQILKALMKNITIVGISRSKKHRDFALELG--ADYVSEMKDAESLINKLTDGLGASIA 242 Query: 214 LDCIGGSYWEKNV-NCLALDGRWVLYGLMG 242 +D +G N+ LA +G +L G+ G Sbjct: 243 IDLVGTEETTYNLGKLLAQEGAIILVGMEG 272 >3COS-A nrPDB Length = 381 Score = 38.1 bits (87), Expect = 0.006, Method: Compositional matrix adjust. Identities = 36/128 (28%), Positives = 57/128 (44%), Gaps = 5/128 (3%) Query: 96 AQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGT 155 +QY V + L I + L + + + T + V G + GL GVG Sbjct: 154 SQYTVVSDINLAKIDDDANLERVCLLGCGFSTGYGAAINNAKVTPGSTCAVF-GLGGVGL 212 Query: 156 AAIQLTRMAGAIPLVTAG-SQKKLQMAEKLGAAAGFNYKK--EDFSEATLKFTKGAGVNL 212 +A+ + AGA ++ + +K A+ LGA N + + E ++ TKG GV+ Sbjct: 213 SAVMGCKAAGASRIIGIDINSEKFVKAKALGATDCLNPRDLHKPIQEVIIELTKG-GVDF 271 Query: 213 ILDCIGGS 220 LDC GGS Sbjct: 272 ALDCAGGS 279 >1YKF-A nrPDB Length = 352 Score = 36.6 bits (83), Expect = 0.016, Method: Compositional matrix adjust. Identities = 57/228 (25%), Positives = 96/228 (42%), Gaps = 41/228 (17%) Query: 19 EVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASN--ILGLEASGHVAELGPGC 76 E KP+PG + +++ A A +D+ ++ G + ILG EA G V E+G Sbjct: 16 EKEKPAPGPFDAIVRPLAVAPCTSDI---HTVFEGAIGERHNMILGHEAVGEVVEVGSEV 72 Query: 77 QGHWKIGDTAM--ALLP---------------GGGQA--QYVTVPEGL------------ 105 + +K GD + A+ P GG A ++ V +G+ Sbjct: 73 K-DFKPGDRVVVPAITPDWRTSEVQRGYHQHSGGMLAGWKFSNVKDGVFGEFFHVNDADM 131 Query: 106 -LMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMA 164 L +P+ + L A IP+ T F L +++ G V + G+ VG A+ ++ Sbjct: 132 NLAHLPKEIPLEAAVMIPDMMTTGFHGAEL-ADIELGATVAV-LGIGPVGLMAVAGAKLR 189 Query: 165 GAIPLVTAGSQKK-LQMAEKLGAAAGFNYKKEDFSEATLKFTKGAGVN 211 GA ++ GS+ + A+ GA NYK + T+G GV+ Sbjct: 190 GAGRIIAVGSRPVCVDAAKYYGATDIVNYKDGPIESQIMNLTEGKGVD 237 >2VNA-A nrPDB Length = 357 Score = 35.8 bits (81), Expect = 0.024, Method: Compositional matrix adjust. Identities = 31/118 (26%), Positives = 63/118 (53%), Gaps = 5/118 (4%) Query: 126 LTAFQLLHLVGNVQAG-DYVLIHAGLSG-VGTAAIQLTRMAGAIPLV-TAGSQKK-LQMA 181 LT+ + G++ AG + ++ +G +G G+ A Q+ G +V G+ +K + + Sbjct: 139 LTSLIGIQEKGHITAGSNKTMVVSGAAGACGSVAGQIGHFLGCSRVVGICGTHEKCILLT 198 Query: 182 EKLGAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIGGSYWEKNVNCLALDGRWVLYG 239 +LG A NYKK++ +E L+ + AGV++ D +GG+ + ++ + + +L G Sbjct: 199 SELGFDAAINYKKDNVAEQ-LRESCPAGVDVYFDNVGGNISDTVISQMNENSHIILCG 255 >4ILK-A nrPDB Length = 359 Score = 35.4 bits (80), Expect = 0.034, Method: Compositional matrix adjust. Identities = 56/232 (24%), Positives = 93/232 (40%), Gaps = 34/232 (14%) Query: 12 PENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNILGLEASGHVAE 71 P L + E P+P GEV +KV + + +D +G ++P ++G E G + Sbjct: 29 PNQLSIIEREIPTPSAGEVRVKVKLAGICGSDSHIYRG-HNPFAKYPRVIGHEFFGVIDA 87 Query: 72 LGPGCQ----------------GH---WKIGD----TAMALL---PGGGQAQYVTVPEGL 105 +G G + GH IG T +A+L GG ++Y VP Sbjct: 88 VGEGVESARVGERVAVDPVVSCGHCYPCSIGKPNVCTTLAVLGVHADGGFSEYAVVPAKN 147 Query: 106 LMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAG 165 IPE + A I + A H G D VL++ G +G +Q+ + Sbjct: 148 AWKIPEAVADQYAVMIEPFTIAANVTGH--GQPTENDTVLVY-GAGPIGLTIVQVLKGVY 204 Query: 166 AIPLVTAGSQ--KKLQMAEKLGAAAGFNYKKEDFSEATLKFTKGAGVNLILD 215 + V + ++L+ A++ GA N + E+ + KG LI+D Sbjct: 205 NVKNVIVADRIDERLEKAKESGADWAINNSQTPLGESFAE--KGIKPTLIID 254 >1HSO-A nrPDB Length = 374 Score = 34.3 bits (77), Expect = 0.076, Method: Compositional matrix adjust. Identities = 37/127 (29%), Positives = 52/127 (40%), Gaps = 7/127 (5%) Query: 96 AQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGT 155 +QY V E + I L + I + T + V V G + GL GVG Sbjct: 147 SQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVF-GLGGVGL 205 Query: 156 AAIQLTRMAGAIPLVTAGSQK-KLQMAEKLGAAAGFN---YKKEDFSEATLKFTKGAGVN 211 +AI + AGA ++ K K A++LGA N YKK + LK GV+ Sbjct: 206 SAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKP--IQEVLKEMTDGGVD 263 Query: 212 LILDCIG 218 + IG Sbjct: 264 FSFEVIG 270 >1F8F-A nrPDB Length = 371 Score = 34.3 bits (77), Expect = 0.082, Method: Compositional matrix adjust. Identities = 22/60 (36%), Positives = 32/60 (53%), Gaps = 3/60 (5%) Query: 25 PGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNILGLEASGHVAELGPGCQGHWKIGD 84 P EVL+KV A+ + DL+ R +Y P A +LG E SG + +GP ++GD Sbjct: 29 PQGDEVLVKVVATGMCHTDLIVRDQKYPVPLPA--VLGHEGSGIIEAIGPNVT-ELQVGD 85 >1HSZ-A nrPDB Length = 374 Score = 33.9 bits (76), Expect = 0.089, Method: Compositional matrix adjust. Identities = 36/127 (28%), Positives = 52/127 (40%), Gaps = 7/127 (5%) Query: 96 AQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGT 155 +QY V E + I L + I + T + V V G + GL GVG Sbjct: 147 SQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVF-GLGGVGL 205 Query: 156 AAIQLTRMAGAIPLVTAGSQK-KLQMAEKLGAAAGFN---YKKEDFSEATLKFTKGAGVN 211 +A+ + AGA ++ K K A++LGA N YKK + LK GV+ Sbjct: 206 SAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKP--IQEVLKEMTDGGVD 263 Query: 212 LILDCIG 218 + IG Sbjct: 264 FSFEVIG 270 >4OH1-A nrPDB Length = 351 Score = 33.1 bits (74), Expect = 0.16, Method: Compositional matrix adjust. Identities = 39/151 (25%), Positives = 64/151 (42%), Gaps = 6/151 (3%) Query: 94 GQAQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGV 153 G ++Y + PIP+ L A + LT + G V I G G+ Sbjct: 129 GFSEYAVYHMSQIFPIPDDADLKDYALVEP--LTVALSSAEQAKISYGKSVAI-MGAGGL 185 Query: 154 GTAAIQLTRMAGAIPLVTAG-SQKKLQMAEKLGAAAGFNYKKEDFSEATLKFTKGAGVNL 212 G +QL R+AGA + +KL++A + GA N +E +E ++ G + Sbjct: 186 GMMLVQLARLAGASTITVFDIVPEKLELALENGADYALNSAEEGVAERAIELA-GGRYDC 244 Query: 213 ILDCIGGSYWEK-NVNCLALDGRWVLYGLMG 242 +L+ G + K + LA DG V + + G Sbjct: 245 VLEGTGATAAAKLGLQLLARDGDAVYFAMYG 275 >1PL8-A nrPDB Length = 356 Score = 33.1 bits (74), Expect = 0.19, Method: Compositional matrix adjust. Identities = 59/253 (23%), Positives = 95/253 (37%), Gaps = 48/253 (18%) Query: 2 LAVHFDKPGGPENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQ----RQGQYDPPPGA 57 L VH GP +L ++ P PG EVLL++ + + +D+ R G + Sbjct: 11 LVVH-----GPGDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFI--VKK 63 Query: 58 SNILGLEASGHVAELGPGCQGHWKIGDTAMALLPG------------------------- 92 +LG EASG V ++G + H K GD +A+ PG Sbjct: 64 PMVLGHEASGTVEKVGSSVK-HLKPGDR-VAIEPGAPRENDEFCKMGRYNLSPSIFFCAT 121 Query: 93 ----GGQAQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHA 148 G ++ +P+ +T + A I + G V G VL+ Sbjct: 122 PPDDGNLCRFYKHNAAFCYKLPDNVTFEEGALIEPLSVGIHACRR--GGVTLGHKVLV-C 178 Query: 149 GLSGVGTAAIQLTRMAGAIP-LVTAGSQKKLQMAEKLGAAAGFNYKKEDFSEATLKFTKG 207 G +G + + + GA +VT S +L A+++GA KE E K Sbjct: 179 GAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQ 238 Query: 208 AGVN--LILDCIG 218 G + ++C G Sbjct: 239 LGCKPEVTIECTG 251 >1U3W-A nrPDB Length = 374 Score = 32.7 bits (73), Expect = 0.23, Method: Compositional matrix adjust. Identities = 35/127 (27%), Positives = 51/127 (40%), Gaps = 7/127 (5%) Query: 96 AQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGT 155 +QY V E + I L + I + T + V V G + GL GVG Sbjct: 147 SQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTPGSTCAVF-GLGGVGL 205 Query: 156 AAIQLTRMAGAIPLVTAGSQK-KLQMAEKLGAAAGFN---YKKEDFSEATLKFTKGAGVN 211 + + + AGA ++ K K A++LGA N YKK + LK GV+ Sbjct: 206 SVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKP--IQEVLKEMTDGGVD 263 Query: 212 LILDCIG 218 + IG Sbjct: 264 FSFEVIG 270 >2CF5-A nrPDB Length = 357 Score = 32.3 bits (72), Expect = 0.26, Method: Compositional matrix adjust. Identities = 40/176 (22%), Positives = 74/176 (42%), Gaps = 18/176 (10%) Query: 80 WKIGDTAMALLPG-GGQAQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNV 138 W D + P GG A+ V + ++ IPEG+ + QAA + A +T + L G Sbjct: 119 WSYNDVYINGQPTQGGFAKATVVHQKFVVKIPEGMAVEQAAPLLCAGVTVYSPLSHFGLK 178 Query: 139 QAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQMAEKLGAAAGFNYKKEDF- 197 Q G I M + ++++ ++K+ + + LGA +D+ Sbjct: 179 QPGLRGGILGLGGVGHMGVKIAKAMGHHVTVISSSNKKREEALQDLGA--------DDYV 230 Query: 198 --SEATLKFTKGAGVNLILDCIGGSY-WEKNVNCLALDGRWVLYGLMGGGDINGPL 250 S+ ++ ++D + + E ++ L LDG+ +L G+ IN PL Sbjct: 231 IGSDQAKMSELADSLDYVIDTVPVHHALEPYLSLLKLDGKLILMGV-----INNPL 281 >3FPL-A nrPDB Length = 351 Score = 32.3 bits (72), Expect = 0.28, Method: Compositional matrix adjust. Identities = 30/119 (25%), Positives = 53/119 (44%), Gaps = 3/119 (2%) Query: 94 GQAQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGV 153 G+ +V + L +P+ + L A I + T F L +++ G V + G+ V Sbjct: 121 GEYFHVNDADMNLAILPKDMPLENAVMITDMMTTGFHGAEL-ADIELGATVAV-LGIGPV 178 Query: 154 GTAAIQLTRMAGAIPLVTAGSQKK-LQMAEKLGAAAGFNYKKEDFSEATLKFTKGAGVN 211 G A+ ++ GA ++ GS+ + A+ GA NYK + T+G GV+ Sbjct: 179 GLMAVAGAKLRGAGRIIAVGSRPVCVDAAKYYGATDIVNYKDGPIESQIMNLTEGKGVD 237 >3WLE-A nrPDB Length = 341 Score = 32.3 bits (72), Expect = 0.30, Method: Compositional matrix adjust. Identities = 55/209 (26%), Positives = 85/209 (40%), Gaps = 37/209 (17%) Query: 25 PGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNILGLEASGHVAELGPGCQGHWKIGD 84 P G++LLKV A L +DL D G + ++G E +G VA +G ++K+GD Sbjct: 34 PKAGQLLLKVDAVGLCHSDLHVIYEGLD--CGDNYVMGHEIAGTVAAVGDDVI-NYKVGD 90 Query: 85 TAMALLPG-----------------------------GGQAQY--VTVPEGLLMPIPEGL 113 + P GG QY VT P L IP+ + Sbjct: 91 RVACVGPNGCGGCKYCRGAIDNVCKNAFGDWFGLGYDGGYQQYLLVTRPRNLSR-IPDNV 149 Query: 114 TLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAG 173 + AAA +A LT + + + + ++ G G+G AIQ+ + GA V Sbjct: 150 SADVAAASTDAVLTPYHAIKMAQVSPTSN--ILLIGAGGLGGNAIQVAKAFGAKVTVLDK 207 Query: 174 SQKKLQMAEKLGAAAGFNYKKEDFSEATL 202 ++ A+KLGA A + E S + Sbjct: 208 KKEARDQAKKLGADAVYETLPESISPGSF 236 >1P0F-A nrPDB Length = 373 Score = 32.0 bits (71), Expect = 0.38, Method: Compositional matrix adjust. Identities = 27/73 (36%), Positives = 37/73 (50%), Gaps = 4/73 (5%) Query: 149 GLSGVGTAAIQLTRMAGAIPLVTAGSQK-KLQMAEKLGAAAGFNYKKED--FSEATLKFT 205 GL GVG +AI + AGA ++ G+ K K A +LGA N K D E + T Sbjct: 199 GLGGVGFSAIVGCKAAGASRIIGVGTHKDKFPKAIELGATECLNPKDYDKPIYEVICEKT 258 Query: 206 KGAGVNLILDCIG 218 G GV+ ++C G Sbjct: 259 NG-GVDYAVECAG 270 >5TNX-A nrPDB Length = 383 Score = 32.0 bits (71), Expect = 0.43, Method: Compositional matrix adjust. Identities = 21/51 (41%), Positives = 29/51 (56%), Gaps = 2/51 (3%) Query: 24 SPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNILGLEASGHVAELGP 74 +P EVL++V A+ L DL+ R QY P P +LG E +G V +GP Sbjct: 39 APRGDEVLVRVVATGLCHTDLIVRD-QYYPVP-LPAVLGHEGAGVVEAVGP 87 >5GXF-A nrPDB Length = 330 Score = 31.6 bits (70), Expect = 0.49, Method: Compositional matrix adjust. Identities = 39/140 (27%), Positives = 57/140 (40%), Gaps = 21/140 (15%) Query: 2 LAVHFDKPGGPENLYVKEVAKPSPGEGEVLLKVAASALNRAD---------LMQRQGQYD 52 L V D+ G VK+++ GEV + V S +N D L+++ Y Sbjct: 5 LVVDKDEESGKTQAAVKQLSLTDLPVGEVTVAVEYSTVNYKDGLCIGPGGGLVRK---YP 61 Query: 53 PPPGASNILGLEASGHVAELGPGCQ---GHWKIGDTAMALLPGGGQAQYVTVPEGLLMPI 109 PG +E S PG + W++G+ GG +Q V L+P+ Sbjct: 62 HVPGIDFAGTVENSSD-ERYKPGDKVVLTGWRVGEAHW-----GGYSQKANVRADWLVPL 115 Query: 110 PEGLTLTQAAAIPEAWLTAF 129 PEGL QA A+ A TA Sbjct: 116 PEGLDTRQAMAVGTAGFTAM 135 >1CDO-A nrPDB Length = 374 Score = 30.8 bits (68), Expect = 0.91, Method: Compositional matrix adjust. Identities = 62/284 (21%), Positives = 98/284 (34%), Gaps = 56/284 (19%) Query: 15 LYVKEVAKPSPGEGEVLLKVAASALNRADLMQR-QGQYDPPPGASNILGLEASGHVAELG 73 L ++E+ P E+ +K+ A+ + DL +G++ G +LG E +G V +G Sbjct: 21 LVIEEIEVDVPHANEIRIKIIATGVCHTDLYHLFEGKHKD--GFPVVLGHEGAGIVESVG 78 Query: 74 PG-------------------------------CQGHWK----------------IGDTA 86 PG C W G Sbjct: 79 PGVTEFQPGEKVIPLFISQCGECRFCQSPKTNQCVKGWANESPDVMSPKETRFTCKGRKV 138 Query: 87 MALLPGGGQAQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLI 146 + L +QY V + + I L + T F V+ G + Sbjct: 139 LQFLGTSTFSQYTVVNQIAVAKIDPSAPLDTVCLLGCGVSTGFGAAVNTAKVEPGSTCAV 198 Query: 147 HAGLSGVGTAAIQLTRMAGAIPLVTAG-SQKKLQMAEKLGAA--AGFNYKKEDFSEATLK 203 GL VG AA+ AGA ++ + K + A+ GA N E S+ K Sbjct: 199 F-GLGAVGLAAVMGCHSAGAKRIIAVDLNPDKFEKAKVFGATDFVNPNDHSEPISQVLSK 257 Query: 204 FTKGAGVNLILDCIGGSYWEKNVNCLALDGRWVLYGLMGGGDIN 247 T G GV+ L+C+G +N L G W + L+G D++ Sbjct: 258 MTNG-GVDFSLECVGNVGVMRNALESCLKG-WGVSVLVGWTDLH 299 >1O89-A nrPDB Length = 345 Score = 30.8 bits (68), Expect = 0.92, Method: Compositional matrix adjust. Identities = 45/187 (24%), Positives = 79/187 (42%), Gaps = 22/187 (11%) Query: 27 EGEVLLKVAASALNRADLMQRQGQYDPPPGASNILGLEASGHVAELGPGCQGH------- 79 EG+V + V S+LN D + G+ I G++ +G V + H Sbjct: 48 EGDVTVDVHWSSLNYKDALAITGKGKIIRNFPMIPGIDFAGTV-RTSEDPRFHAGQEVLL 106 Query: 80 --WKIGDTAMALLPGGGQAQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGN 137 W +G+ GG A+ V L+ +P+GL +A I A TA + + + Sbjct: 107 TGWGVGENHW-----GGLAEQARVKGDWLVAMPQGLDARKAMIIGTAGFTAMLCVMALED 161 Query: 138 V----QAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQMAEKLGAAAGFNYK 193 Q G+ V+ A GVG+ A+ L G + +G + + + LGA+ Sbjct: 162 AGVRPQDGEIVVTGAS-GGVGSTAVALLHKLGYQVVAVSGRESTHEYLKSLGASRVL--P 218 Query: 194 KEDFSEA 200 +++F+E+ Sbjct: 219 RDEFAES 225 >1Q1N-A nrPDB Length = 360 Score = 30.8 bits (68), Expect = 0.96, Method: Compositional matrix adjust. Identities = 31/94 (32%), Positives = 46/94 (48%), Gaps = 2/94 (2%) Query: 93 GGQAQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSG 152 GG A YV V E ++PIPE + AA + LT + LV N + GL G Sbjct: 133 GGYANYVRVHEHFVVPIPENIPSHLAAPLLCGGLTVYSP--LVRNGCGPGKKVGIVGLGG 190 Query: 153 VGTAAIQLTRMAGAIPLVTAGSQKKLQMAEKLGA 186 +G+ +++ GA V + S +K + A K+GA Sbjct: 191 IGSMGTLISKAMGAETYVISRSSRKREDAMKMGA 224 >3QE3-A nrPDB Length = 355 Score = 30.4 bits (67), Expect = 1.1, Method: Compositional matrix adjust. Identities = 29/84 (34%), Positives = 45/84 (53%), Gaps = 4/84 (4%) Query: 11 GPENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQ-GQY-DPPPGASNILGLEASGH 68 GP +L ++ P PG EVLLK+ + + +D+ Q G+ D +LG EASG Sbjct: 14 GPGDLRLENYPIPEPGPNEVLLKMHSVGICGSDVHYWQHGRIGDFVVKKPMVLGHEASGT 73 Query: 69 VAELGPGCQGHWKIGDTAMALLPG 92 V ++G + H + GD +A+ PG Sbjct: 74 VVKVGSLVR-HLQPGDR-VAIQPG 95 >1EE2-A nrPDB Length = 373 Score = 30.0 bits (66), Expect = 1.5, Method: Compositional matrix adjust. Identities = 62/255 (24%), Positives = 95/255 (37%), Gaps = 57/255 (22%) Query: 15 LYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNILGLEASGHVAELGP 74 ++EV P EV +K+ A+ + R+D G P I G EA+G V +G Sbjct: 21 FSIEEVEVAPPKAHEVRIKMVAAGICRSDDHVVSGTLVAP--LPVIAGHEAAGIVESIGE 78 Query: 75 GCQGHWKIGDTAMAL-LPGGGQAQYVTVPEGLL----MPIPEGL---------------- 113 G + GD + L +P G+ PEG L + +P G Sbjct: 79 GVT-TVRPGDKVIPLFIPQCGKCSVCKHPEGNLCLKNLSMPRGTMQDGTSRFTCRGKPIH 137 Query: 114 ------TLTQAAAIPEAWL------TAFQLLHLVG--------------NVQAGDYVLIH 147 T +Q + E + + + + LVG V G + Sbjct: 138 HFLGTSTFSQYTVVDEISVAKIDAASPLEKVCLVGCGFSTGYGSAVKVAKVTQGSTCAVF 197 Query: 148 AGLSGVGTAAIQLTRMAGAIPLVTAGSQK-KLQMAEKLGAAAGFN---YKKEDFSEATLK 203 GL GVG + I + AGA ++ K K A+++GA N YKK E + Sbjct: 198 -GLGGVGLSVIMGCKAAGAARIIGVDINKDKFAKAKEVGATECVNPQDYKKP-IQEVLTE 255 Query: 204 FTKGAGVNLILDCIG 218 + G GV+ + IG Sbjct: 256 MSNG-GVDFSFEVIG 269 >4JLW-A nrPDB Length = 399 Score = 28.9 bits (63), Expect = 3.2, Method: Compositional matrix adjust. Identities = 19/55 (34%), Positives = 31/55 (56%), Gaps = 3/55 (5%) Query: 30 VLLKVAASALNRADLMQRQGQYDPPPGASNILGLEASGHVAELGPGCQGHWKIGD 84 V+L+V ++ + +D +G+ P G +LG E +G V E+G G + KIGD Sbjct: 37 VILRVVSTNICGSDQHMVRGRTTAPEGL--VLGHEITGEVVEIGRGVE-TMKIGD 88 >1LTX-R nrPDB Length = 650 Score = 28.1 bits (61), Expect = 5.3, Method: Compositional matrix adjust. Identities = 14/34 (41%), Positives = 20/34 (58%) Query: 243 GGDINGPLFSKLLFKRGSLITSLLRSRDNKYKQM 276 G N L SKLL+ RG LI L++S ++Y + Sbjct: 221 GRRFNIDLVSKLLYSRGLLIDLLIKSNVSRYAEF 254 >4OAQ-A nrPDB Length = 367 Score = 28.1 bits (61), Expect = 5.5, Method: Compositional matrix adjust. Identities = 53/198 (26%), Positives = 80/198 (40%), Gaps = 8/198 (4%) Query: 93 GGQAQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSG 152 GG + + E + IPE L + A + A +T F L + A + G+ G Sbjct: 137 GGYSSHSIADEKFVFAIPEDLPSSYGAPLMCAGITVFSPLIRNLGLDARGKNVGIIGIGG 196 Query: 153 VGTAAIQLTRMAGAIPLVTAGSQKKLQMAEKLGAAAGFNYKKEDFSEATLKFTKGAGVNL 212 +G A+Q GA + S K + A KLG A F ED T + Sbjct: 197 LGHLALQFANAMGANVTAFSRSSSKKEQAMKLG-AHDFVATGED---KTWYKNYDDHFDF 252 Query: 213 ILDC---IGGSYWEKNVNCLALDGRWVLYGLMGGGDINGPLFSKLLFKRGSLITSLLRSR 269 IL+C I G + ++ L +D ++V GL D L + S +SLL S+ Sbjct: 253 ILNCASGIDGLNLSEYLSTLKVDKKFVSVGLPPSEDKFEVSPFTFLQQGASFGSSLLGSK 312 Query: 270 DNKYKQMLVNAFTEQILP 287 + K+ML A + P Sbjct: 313 -TEVKEMLNLAAKHNVRP 329 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 2OBY-A nrPDB 390 e-109 4A27-A nrPDB 273 5e-74 4RVS-A nrPDB 273 9e-74 1YB5-A nrPDB 272 2e-73 3PII-A nrPDB 270 4e-73 3QWB-A nrPDB 264 4e-71 1WLY-A nrPDB 263 6e-71 1QOR-A nrPDB 263 9e-71 1LLU-A nrPDB 261 4e-70 3MEQ-A nrPDB 260 5e-70 5K1S-A nrPDB 257 6e-69 4Z6K-A nrPDB 256 1e-68 6N7L-A nrPDB 251 4e-67 5ENV-A nrPDB 249 8e-67 3JYN-A nrPDB 249 1e-66 2WEK-A nrPDB 248 2e-66 3S2F-A nrPDB 248 3e-66 2EER-A nrPDB 246 1e-65 3TQH-A nrPDB 245 2e-65 5YAT-A nrPDB 241 3e-64 3UOG-A nrPDB 230 7e-61 4J6F-A nrPDB 228 3e-60 4EYE-A nrPDB 226 1e-59 1R37-A nrPDB 223 1e-58 1H2B-A nrPDB 213 8e-56 4EEZ-A nrPDB 213 9e-56 3FBG-A nrPDB 213 1e-55 2DFV-A nrPDB 210 9e-55 2VCY-A nrPDB 209 1e-54 3SLK-A nrPDB 209 1e-54 4DVJ-A nrPDB 206 1e-53 3GFB-A nrPDB 202 1e-52 2VN8-A nrPDB 202 2e-52 5A3V-A nrPDB 202 2e-52 4GKV-A nrPDB 199 2e-51 3HZZ-A nrPDB 191 3e-49 2H6E-A nrPDB 189 1e-48 4A10-A nrPDB 187 4e-48 4IDE-A nrPDB 183 8e-47 4EJ6-A nrPDB 181 3e-46 2DQ4-A nrPDB 179 2e-45 5LB9-A nrPDB 174 4e-44 6FG0-A nrPDB 174 5e-44 5VM2-A nrPDB 171 3e-43 4Y1B-A nrPDB 169 1e-42 2J3K-A nrPDB 167 8e-42 3B70-A nrPDB 157 4e-39 3FPC-A nrPDB 155 3e-38 3FSR-A nrPDB 154 4e-38 1V3V-A nrPDB 153 1e-37 3IP1-A nrPDB 152 2e-37 1MC5-A nrPDB 152 2e-37 1KEV-A nrPDB 150 8e-37 2Y05-A nrPDB 144 4e-35 2OUI-A nrPDB 140 6e-34 Sequences not found previously or not previously below threshold: 1HSO-A nrPDB 156 1e-38 1PL8-A nrPDB 155 2e-38 4CPD-A nrPDB 155 2e-38 1U3W-A nrPDB 153 9e-38 1HSZ-A nrPDB 151 3e-37 3COS-A nrPDB 150 5e-37 5KIA-A nrPDB 150 7e-37 5TNX-A nrPDB 148 3e-36 4OH1-A nrPDB 147 5e-36 3QE3-A nrPDB 147 6e-36 1F8F-A nrPDB 144 4e-35 1YKF-A nrPDB 144 5e-35 4RQU-A nrPDB 141 4e-34 1E3J-A nrPDB 141 4e-34 1E3E-A nrPDB 140 5e-34 3FPL-A nrPDB 140 6e-34 4DLA-A nrPDB 140 6e-34 1EE2-A nrPDB 139 2e-33 5YLN-A nrPDB 139 2e-33 1D1T-A nrPDB 137 5e-33 4JJI-A nrPDB 136 2e-32 1CDO-A nrPDB 135 2e-32 4ILK-A nrPDB 134 8e-32 1UUF-A nrPDB 133 9e-32 3WLE-A nrPDB 130 9e-31 1P0F-A nrPDB 130 9e-31 4OAQ-A nrPDB 129 2e-30 1Q1N-A nrPDB 125 2e-29 2VNA-A nrPDB 125 3e-29 4UEJ-A nrPDB 124 6e-29 3TWO-A nrPDB 122 2e-28 1YQX-A nrPDB 121 5e-28 2ZB3-A nrPDB 118 3e-27 5Z0C-A nrPDB 118 3e-27 1O89-A nrPDB 117 8e-27 5FI5-A nrPDB 117 1e-26 5VKT-A nrPDB 116 2e-26 6C49-A nrPDB 113 1e-25 5GXF-A nrPDB 112 2e-25 3M6I-A nrPDB 105 4e-23 5H82-A nrPDB 102 3e-22 2CF5-A nrPDB 94 7e-20 6DKH-A nrPDB 92 3e-19 5H83-A nrPDB 92 4e-19 2VWH-A nrPDB 78 7e-15 2DPH-A nrPDB 78 7e-15 4JLW-A nrPDB 77 1e-14 1KOL-A nrPDB 67 1e-11 2CDC-A nrPDB 59 4e-09 3WID-A nrPDB 50 1e-06 3D3W-A nrPDB 39 0.002 4INE-A nrPDB 39 0.002 3RSH-A nrPDB 38 0.005 5TQV-A nrPDB 38 0.006 4X3Q-A nrPDB 38 0.006 3PWS-A nrPDB 36 0.019 3F9I-A nrPDB 36 0.021 4ER3-A nrPDB 36 0.029 3UWP-A nrPDB 36 0.029 3PPI-A nrPDB 35 0.037 1XLT-A nrPDB 35 0.042 5JJC-A nrPDB 35 0.046 3DWF-A nrPDB 35 0.051 4AEC-A nrPDB 35 0.055 1Q7C-A nrPDB 35 0.063 5PGZ-A nrPDB 34 0.074 5YWN-A nrPDB 34 0.081 5ILO-A nrPDB 34 0.085 3DLC-A nrPDB 34 0.092 4KRI-A nrPDB 34 0.11 1X14-A nrPDB 34 0.12 5B6K-A nrPDB 34 0.13 5ITV-A nrPDB 34 0.14 3NJ4-A nrPDB 34 0.14 3T4P-A nrPDB 33 0.16 3EMK-A nrPDB 33 0.19 5T5Q-A nrPDB 33 0.20 4AVY-A nrPDB 33 0.21 5CDY-A nrPDB 33 0.23 2ISQ-A nrPDB 33 0.24 4EUF-A nrPDB 32 0.26 1DIR-A nrPDB 32 0.27 6FOC-D nrPDB 32 0.29 1HXH-A nrPDB 32 0.33 4DIO-A nrPDB 32 0.37 5IJZ-A nrPDB 32 0.38 1BDB-A nrPDB 32 0.41 4OAU-C nrPDB 32 0.45 2YFH-A nrPDB 32 0.45 1AE1-A nrPDB 32 0.46 3WMF-A nrPDB 32 0.50 3UXA-A nrPDB 32 0.50 3VPX-A nrPDB 32 0.54 3OND-A nrPDB 32 0.55 3GDF-A nrPDB 32 0.55 3VZS-A nrPDB 31 0.59 4M8S-A nrPDB 31 0.61 2NNL-D nrPDB 31 0.70 5B1I-A nrPDB 31 0.77 4K2X-A nrPDB 31 0.78 4HP8-A nrPDB 31 0.84 6GBN-A nrPDB 31 0.88 6GCS-E nrPDB 31 0.89 4LIS-A nrPDB 31 0.92 4FIO-A nrPDB 31 0.92 5EES-A nrPDB 31 0.95 2Q2Q-A nrPDB 30 1.00 3F4W-A nrPDB 30 1.1 3GRP-A nrPDB 30 1.1 6C55-A nrPDB 30 1.1 3RWB-A nrPDB 30 1.1 2B4Q-A nrPDB 30 1.2 4FHN-X nrPDB 30 1.2 1V9L-A nrPDB 30 1.3 4R1U-A nrPDB 30 1.3 6GME-A nrPDB 30 1.3 1URG-A nrPDB 30 1.4 3L9X-A nrPDB 30 1.7 3TC6-A nrPDB 30 1.8 2UVD-A nrPDB 30 1.8 4R1T-A nrPDB 29 2.2 5YSS-A nrPDB 29 2.3 2O23-A nrPDB 29 2.3 2XOK-D nrPDB 29 2.4 4B4O-A nrPDB 29 2.5 1CYD-A nrPDB 29 2.8 3ORF-A nrPDB 29 2.9 2VHY-A nrPDB 29 3.0 1BW9-B nrPDB 29 3.0 3EZL-A nrPDB 29 3.2 5FL7-D nrPDB 29 3.4 5UJU-A nrPDB 29 3.5 2P91-A nrPDB 29 3.5 2DVL-A nrPDB 29 3.7 2EEZ-A nrPDB 28 3.8 4OMU-A nrPDB 28 4.0 1ZZE-A nrPDB 28 4.1 1OOE-A nrPDB 28 4.4 3QVK-A nrPDB 28 4.4 2C82-A nrPDB 28 5.1 3ZV3-A nrPDB 28 5.5 4IIN-A nrPDB 28 6.0 2YVG-A nrPDB 28 6.0 6J0Z-C nrPDB 28 6.1 1W1U-A nrPDB 28 6.2 4GBJ-A nrPDB 28 6.3 2EXX-A nrPDB 28 6.6 5XA2-A nrPDB 28 6.7 4BO1-A nrPDB 28 6.7 4NBT-A nrPDB 28 6.7 4LZJ-A nrPDB 28 7.1 5VMT-A nrPDB 27 8.3 1YXM-A nrPDB 27 8.4 1LU9-A nrPDB 27 9.7 >2OBY-A nrPDB Length = 338 Score = 390 bits (1003), Expect = e-109, Method: Composition-based stats. Identities = 332/332 (100%), Positives = 332/332 (100%) Query: 1 MLAVHFDKPGGPENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNI 60 MLAVHFDKPGGPENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNI Sbjct: 7 MLAVHFDKPGGPENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNI 66 Query: 61 LGLEASGHVAELGPGCQGHWKIGDTAMALLPGGGQAQYVTVPEGLLMPIPEGLTLTQAAA 120 LGLEASGHVAELGPGCQGHWKIGDTAMALLPGGGQAQYVTVPEGLLMPIPEGLTLTQAAA Sbjct: 67 LGLEASGHVAELGPGCQGHWKIGDTAMALLPGGGQAQYVTVPEGLLMPIPEGLTLTQAAA 126 Query: 121 IPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQM 180 IPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQM Sbjct: 127 IPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQM 186 Query: 181 AEKLGAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIGGSYWEKNVNCLALDGRWVLYGL 240 AEKLGAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIGGSYWEKNVNCLALDGRWVLYGL Sbjct: 187 AEKLGAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIGGSYWEKNVNCLALDGRWVLYGL 246 Query: 241 MGGGDINGPLFSKLLFKRGSLITSLLRSRDNKYKQMLVNAFTEQILPHFSTEGPQRLLPV 300 MGGGDINGPLFSKLLFKRGSLITSLLRSRDNKYKQMLVNAFTEQILPHFSTEGPQRLLPV Sbjct: 247 MGGGDINGPLFSKLLFKRGSLITSLLRSRDNKYKQMLVNAFTEQILPHFSTEGPQRLLPV 306 Query: 301 LDRIYPVTEIQEAHKYMEANKNIGKIVLELPQ 332 LDRIYPVTEIQEAHKYMEANKNIGKIVLELPQ Sbjct: 307 LDRIYPVTEIQEAHKYMEANKNIGKIVLELPQ 338 >4A27-A nrPDB Length = 349 Score = 273 bits (699), Expect = 5e-74, Method: Composition-based stats. Identities = 99/348 (28%), Positives = 169/348 (48%), Gaps = 23/348 (6%) Query: 1 MLAVHFDKPGGPENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNI 60 M AV GG L + A P P +GE+ ++V A LN DLM RQG D PP + Sbjct: 4 MRAVVLAGFGGLNKLRLFRKAMPEPQDGELKIRVKACGLNFIDLMVRQGNIDNPPKTPLV 63 Query: 61 LGLEASGHVAELGPGCQGHWKIGDTAMALLPGGGQAQYVTVPEGLLMPIPEGLTLTQAAA 120 G E SG V LG +G ++IGD MA + A+ V P + IP+ ++ ++AAA Sbjct: 64 PGFECSGIVEALGDSVKG-YEIGDRVMAFVNYNAWAEVVCTPVEFVYKIPDDMSFSEAAA 122 Query: 121 IPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQM 180 P ++TA+ +L V N++ G VL+H+ GVG A QL +P VT Sbjct: 123 FPMNFVTAYVMLFEVANLREGMSVLVHSAGGGVGQAVAQLC---STVPNVTVFGTASTFK 179 Query: 181 AEKLGAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIGGSYWEKNVNCLALDGRWVLYG- 239 E + + + + +K GV+++LDC+ G K ++ L G ++LYG Sbjct: 180 HEAIKDSVTHLFDRNADYVQEVKRISAEGVDIVLDCLCGDNTGKGLSLLKPLGTYILYGS 239 Query: 240 --LMGGGDINGPLFSKL-----------LFKRGSLIT--SLLRSRDNKYKQMLVNAFTEQ 284 ++ G + F+K L++ +I SLL + + L+ E+ Sbjct: 240 SNMVTGETKSFFSFAKSWWQVEKVNPIKLYEENKVIAGFSLLNLLFKQGRAGLIRGVVEK 299 Query: 285 ILPHFSTEGPQRLLPVLDRIYPVTEIQEAHKYMEANKNIGKIVLELPQ 332 ++ ++ +++ PV+D ++ + E++EA + + NIGK++L++ + Sbjct: 300 LIGLYNQ---KKIKPVVDSLWALEEVKEAMQRIHDRGNIGKLILDVEK 344 >4RVS-A nrPDB Length = 329 Score = 273 bits (698), Expect = 9e-74, Method: Composition-based stats. Identities = 93/333 (27%), Positives = 150/333 (45%), Gaps = 12/333 (3%) Query: 1 MLAVHFDKPGGPENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNI 60 M A+ + GGP L + +P PG GE+L+K A +N D R GQY P + Sbjct: 2 MHAIEVTETGGPGVLRHVDQPQPQPGHGELLIKAEAIGVNFIDTYFRSGQY--PRELPFV 59 Query: 61 LGLEASGHVAELGPGCQGH---WKIGDTAMALLPGGGQAQYVTVPEGLLMPIPEGLTLTQ 117 +G E G V +GPG +GD ++ G A++ T P L +P+ +T Sbjct: 60 IGSEVCGTVEAVGPGVTAADTAISVGDRVVSASANGAYAEFCTAPASLTAKVPDDVTSEV 119 Query: 118 AAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKK 177 AA+ LTA LL V V+ GD VL+HAG GVG Q G + T + +K Sbjct: 120 AASALLKGLTAHYLLKSVYPVKRGDTVLVHAGAGGVGLILTQWATHLGVRVITTVSTAEK 179 Query: 178 LQMAEKLGAAAGFNYKKE--DFSEATLKFTKGAGVNLILDCIGGSYWEKNVNCLALDGRW 235 ++++ GA +Y ++ F+ + T G GV + D +G + ++ ++ LA+ G Sbjct: 180 AKLSKDAGADVVLDYPEDAWQFAGRVRELTGGTGVQAVYDGVGATTFDASLASLAVRGTL 239 Query: 236 VLYGLMGGGDINGPLFSKLLFKRGSLITSLLRSRDNKYKQMLVNAFTEQILPHFSTEGPQ 295 L+G G P+ + L GS+ + F+ + F G + Sbjct: 240 ALFGAASGP--VPPVDPQRLNAAGSVYLTRPSLFHFTRTG---EEFSWRAAELFDAIGNE 294 Query: 296 RLLPVLDRIYPVTEIQEAHKYMEANKNIGKIVL 328 + + YP+ + AH+ +EA K +G +VL Sbjct: 295 AITVAVGGRYPLADALRAHQDLEARKTVGSVVL 327 >1YB5-A nrPDB Length = 351 Score = 272 bits (695), Expect = 2e-73, Method: Composition-based stats. Identities = 93/333 (27%), Positives = 160/333 (48%), Gaps = 14/333 (4%) Query: 1 MLAVHFDKPGGPENLYVK-EVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASN 59 M AV + GGPE L ++ ++A P P + +VL+KV A +N + R G Y P Sbjct: 30 MRAVRVFEFGGPEVLKLRSDIAVPIPKDHQVLIKVHACGVNPVETYIRSGTYSRKPLLPY 89 Query: 60 ILGLEASGHVAELGPGCQGHWKIGDTA-MALLPGGGQAQYVTVPEGLLMPIPEGLTLTQA 118 G + +G + +G +K GD + GG A+Y + + +PE L Q Sbjct: 90 TPGSDVAGVIEAVGDNASA-FKKGDRVFTSSTISGGYAEYALAADHTVYKLPEKLDFKQG 148 Query: 119 AAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKL 178 AAI + TA++ L V+AG+ VL+H GVG AA Q+ R G L TAG+++ Sbjct: 149 AAIGIPYFTAYRALIHSACVKAGESVLVHGASGGVGLAACQIARAYGLKILGTAGTEEGQ 208 Query: 179 QMAEKLGAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIGGSYWEKNVNCLALDGRWVLY 238 ++ + GA FN+++ ++ + K+ G+++I++ + K+++ L+ GR ++ Sbjct: 209 KIVLQNGAHEVFNHREVNYIDKIKKYVGEKGIDIIIEMLANVNLSKDLSLLSHGGRVIVV 268 Query: 239 GLMGGGDINGPLFSKLLFKRGSLITSLLRSRDNKYKQMLVNAFTEQILPHFSTEGPQRLL 298 G G +IN + K S+I L S + Q A + + L Sbjct: 269 GSRGTIEIN---PRDTMAKESSIIGVTLFSSTKEEFQQYAAALQAGMEIGW-------LK 318 Query: 299 PVLDRIYPVTEIQEAHK-YMEANKNIGKIVLEL 330 PV+ YP+ ++ EAH+ + + GK++L L Sbjct: 319 PVIGSQYPLEKVAEAHENIIHGSGATGKMILLL 351 >3PII-A nrPDB Length = 339 Score = 270 bits (691), Expect = 4e-73, Method: Composition-based stats. Identities = 88/359 (24%), Positives = 151/359 (42%), Gaps = 50/359 (13%) Query: 1 MLAVHFDKPGGPENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNI 60 M A ++ P L +KEV KP+ GEVL+++ A + DL G + P I Sbjct: 1 MKAAVVEQFKEP--LKIKEVEKPTISYGEVLVRIKACGVCHTDLHAAHGDWPVKPKLPLI 58 Query: 61 LGLEASGHVAELGPGCQGHWKIGDTA----------------------------MALLPG 92 G E G V E+GPG H K+GD Sbjct: 59 PGHEGVGIVEEVGPGVT-HLKVGDRVGIPWLYSACGHCDYCLSGQETLCEHQKNAGYSVD 117 Query: 93 GGQAQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSG 152 GG A+Y ++ IP+ L+ +AA I A +T ++ L + G + G++V I+ G+ G Sbjct: 118 GGYAEYCRAAADYVVKIPDNLSFEEAAPIFCAGVTTYKALKVTGA-KPGEWVAIY-GIGG 175 Query: 153 VGTAAIQLTRMAGAIPLVTAGSQKKLQMAEKLGAAAGFNYKKEDFSEATLKFTKGAGVNL 212 G A+Q + G + +KL++A++LGA N KED ++ + G + Sbjct: 176 FGHVAVQYAKAMGLNVVAVDIGDEKLELAKELGADLVVNPLKEDAAKFMKEKVGGVHAAV 235 Query: 213 ILDCIGGSYWEKNVNCLALDGRWVLYGLMGGGDINGPLFSKLLFKRGSLITSLLRSRDNK 272 + + ++ N + G VL GL ++ P+F +L +I S++ +R + Sbjct: 236 V-TAVSKPAFQSAYNSIRRGGACVLVGLP-PEEMPIPIFDTVLN-GIKIIGSIVGTRKDL 292 Query: 273 YKQMLVNAFTEQILPHFSTEGPQRLLPVLDRIYPVTEIQEAHKYMEANKNIGKIVLELP 331 + + F+ EG + + + P+ +I E M + G++VL L Sbjct: 293 QEAL-----------QFAAEGKVKT---IIEVQPLEKINEVFDRMLKGQINGRVVLTLE 337 >3QWB-A nrPDB Length = 334 Score = 264 bits (675), Expect = 4e-71, Method: Composition-based stats. Identities = 96/339 (28%), Positives = 156/339 (46%), Gaps = 22/339 (6%) Query: 2 LAVHFDKPGGPENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNIL 61 + D+ GG + + ++ PS E E+L+K + +N + R+G Y P +L Sbjct: 10 KVILIDEIGGYDVIKYEDYPVPSISEEELLIKNKYTGVNYIESYFRKGIY--PCEKPYVL 67 Query: 62 GLEASGHVAELGPGCQGHWKIGDTAMALLPGGGQAQYVTVP-EGLLMPIPEGLTLTQ--- 117 G EASG V G G ++++GD A + AQY + +G +M +P+G + + Sbjct: 68 GREASGTVVAKGKGVT-NFEVGDQV-AYISNSTFAQYSKISSQGPVMKLPKGTSDEELKL 125 Query: 118 AAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKK 177 AA LTA + +V+ GDYVL+ A GVG QL +M GA + A + +K Sbjct: 126 YAAGLLQVLTALSFTNEAYHVKKGDYVLLFAAAGGVGLILNQLLKMKGAHTIAVASTDEK 185 Query: 178 LQMAEKLGAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIGGSYWEKNVNCLALDGRWVL 237 L++A++ GA N KED LKFT G GV+ D +G +E ++ L G +V Sbjct: 186 LKIAKEYGAEYLINASKEDILRQVLKFTNGKGVDASFDSVGKDTFEISLAALKRKGVFVS 245 Query: 238 YGLMGGGDINGPL----FSKLLFKRGSLITSLLRSRDNKYKQMLVNAFTEQILPHFSTEG 293 +G G + + R L + + KY F Sbjct: 246 FGNASGLIPPFSITRLSPKNITLVRPQLYGYIADPEEWKYYSD----------EFFGLVN 295 Query: 294 PQRLLPVLDRIYPVTEIQEAHKYMEANKNIGKIVLELPQ 332 ++L + + YP+ + + A +E+ K +GK+VLE+PQ Sbjct: 296 SKKLNIKIYKTYPLRDYRTAAADIESRKTVGKLVLEIPQ 334 >1WLY-A nrPDB Length = 333 Score = 263 bits (673), Expect = 6e-71, Method: Composition-based stats. Identities = 108/337 (32%), Positives = 153/337 (45%), Gaps = 11/337 (3%) Query: 1 MLAVHFDKPGGPENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPP--PGAS 58 ++A K GGP+N +EV SPG G+V L+ A +N D R G P Sbjct: 2 VMAAVIHKKGGPDNFVWEEVKVGSPGPGQVRLRNTAIGVNFLDTYHRAGIPHPLVVGEPP 61 Query: 59 NILGLEASGHVAELGPGCQGHWKIGDTAMALLPG-GGQAQYVTVPEGLLMPIPEGLTLTQ 117 ++G EA+ V E+GPG + +G+ LP G +Q P L+ +P+ L L Sbjct: 62 IVVGFEAAAVVEEVGPGVT-DFTVGERVCTCLPPLGAYSQERLYPAEKLIKVPKDLDLDD 120 Query: 118 A--AAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQ 175 A + +TA LLH V+ GDYVLIHA G+G + R GA + T ++ Sbjct: 121 VHLAGLMLKGMTAQYLLHQTHKVKPGDYVLIHAAAGGMGHIMVPWARHLGATVIGTVSTE 180 Query: 176 KKLQMAEKLGAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIGGSYWEKNVNCLALDGRW 235 +K + A KLG NY +DF+E + T G GV+++ D IG +K+++CL G Sbjct: 181 EKAETARKLGCHHTINYSTQDFAEVVREITGGKGVDVVYDSIGKDTLQKSLDCLRPRGMC 240 Query: 236 VLYGLMGGGDINGPLFSKLLFKRGSLITSLLRSRDNKYKQMLVNAFTEQILPHFSTEGPQ 295 YG G + L RGSL + R Y E F Sbjct: 241 AAYGHASGVADPIRVVED-LGVRGSL--FITRPALWHYMSNRSE-IDEGSKCLFDAVKAG 296 Query: 296 RLLPVLDRIYPVTEIQEAHKYMEANKNIGKIVLELPQ 332 L + + +P+ E AHKYM + IG IVL LPQ Sbjct: 297 VLHSSVAKTFPLREAAAAHKYMGGRQTIGSIVL-LPQ 332 >1QOR-A nrPDB Length = 327 Score = 263 bits (672), Expect = 9e-71, Method: Composition-based stats. Identities = 96/327 (29%), Positives = 148/327 (45%), Gaps = 8/327 (2%) Query: 4 VHFDKPGGPENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNILGL 63 + F K GGPE L E P E E+ ++ A +N D R G Y PPP + LG Sbjct: 5 IEFHKHGGPEVLQAVEFTPADPAENEIQVENKAIGINFIDTYIRSGLY-PPPSLPSGLGT 63 Query: 64 EASGHVAELGPGCQGHWKIGDTAMALLPG-GGQAQYVTVPEGLLMPIPEGLTLTQAAAIP 122 EA+G V+++G G + H K GD + G + + +P ++ QAAA Sbjct: 64 EAAGIVSKVGSGVK-HIKAGDRVVYAQSALGAYSSVHNIIADKAAILPAAISFEQAAASF 122 Query: 123 EAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQMAE 182 LT + LL ++ + L HA GVG A Q + GA + T G+ +K Q A Sbjct: 123 LKGLTVYYLLRKTYEIKPDEQFLFHAAAGGVGLIACQWAKALGAKLIGTVGTAQKAQSAL 182 Query: 183 KLGAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIGGSYWEKNVNCLALDGRWVLYGLMG 242 K GA NY++ED E + T G V ++ D +G WE++++CL G V +G Sbjct: 183 KAGAWQVINYREEDLVERLKEITGGKKVRVVYDSVGRDTWERSLDCLQRRGLMVSFGNSS 242 Query: 243 GGDINGPLFSKLLFKRGSLITSLLRSR-DNKYKQMLVNAFTEQILPHFSTEGPQRLLPVL 301 G L +L ++GSL + + ++ L A E L G ++ Sbjct: 243 GAVTGVNL--GILNQKGSLYVTRPSLQGYITTREELTEASNE--LFSLIASGVIKVDVAE 298 Query: 302 DRIYPVTEIQEAHKYMEANKNIGKIVL 328 + YP+ + Q AH+ +E+ G +L Sbjct: 299 QQKYPLKDAQRAHEILESRATQGSSLL 325 >1LLU-A nrPDB Length = 342 Score = 261 bits (666), Expect = 4e-70, Method: Composition-based stats. Identities = 91/358 (25%), Positives = 147/358 (41%), Gaps = 50/358 (13%) Query: 1 MLAVHFDKPGGPENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNI 60 M A G P L ++EV P PG G+VL+K+ AS + DL +G + P I Sbjct: 7 MKAAVVHAYGAP--LRIEEVKVPLPGPGQVLVKIEASGVCHTDLHAAEGDWPVKPPLPFI 64 Query: 61 LGLEASGHVAELGPGCQGHWKIGDTA----------------------------MALLPG 92 G E G+VA +G G K GD Sbjct: 65 PGHEGVGYVAAVGSGVT-RVKEGDRVGIPWLYTACGCCEHCLTGWETLCESQQNTGYSVN 123 Query: 93 GGQAQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSG 152 GG A+YV + +P+ + + A I A +T ++ L N + G +V I +G+ G Sbjct: 124 GGYAEYVLADPNYVGILPKNVEFAEIAPILCAGVTVYKGLKQT-NARPGQWVAI-SGIGG 181 Query: 153 VGTAAIQLTRMAGAIPLVTAGSQKKLQMAEKLGAAAGFNYKKEDFSEATLKFTKGAGVNL 212 +G A+Q R G KL++A KLGA+ N ++ED EA + GA + Sbjct: 182 LGHVAVQYARAMGLHVAAIDIDDAKLELARKLGASLTVNARQEDPVEAIQRDIGGAH-GV 240 Query: 213 ILDCIGGSYWEKNVNCLALDGRWVLYGLMGGGDINGPLFSKLLFKRGSLITSLLRSRDNK 272 ++ + S + + + G L GL GD P+F +L K + S++ +R + Sbjct: 241 LVTAVSNSAFGQAIGMARRGGTIALVGLP-PGDFPTPIFDVVL-KGLHIAGSIVGTRADL 298 Query: 273 YKQMLVNAFTEQILPHFSTEGPQRLLPVLDRIYPVTEIQEAHKYMEANKNIGKIVLEL 330 + + F+ EG + + + +I + M A + G+IVLE+ Sbjct: 299 QEAL-----------DFAGEGLVKATIHPGK---LDDINQILDQMRAGQIEGRIVLEM 342 >3MEQ-A nrPDB Length = 365 Score = 260 bits (665), Expect = 5e-70, Method: Composition-based stats. Identities = 83/361 (22%), Positives = 144/361 (39%), Gaps = 50/361 (13%) Query: 1 MLAVHFDKPGGPENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNI 60 M A G P L + EV P PG G++ + + AS + DL +G + P I Sbjct: 26 MKAAVVRAFGKP--LTIDEVPIPQPGPGQIQVAIQASGVCHTDLHAAEGDWPVKPNPPFI 83 Query: 61 LGLEASGHVAELGPGCQGHWKIGDTA----------------------------MALLPG 92 G E G V+ +G G + H K GD Sbjct: 84 PGHEGVGFVSAVGSGVK-HVKEGDRVGIPWLYTACGHCRHCLGGWETLCEEQLNTGYSVN 142 Query: 93 GGQAQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSG 152 GG A+YV + +P+ + + A + A +T ++ L V + + GD+V+I +G+ G Sbjct: 143 GGFAEYVVADPNFVGHLPKNIDFNEIAPVLCAGVTVYKGLK-VTDTKPGDWVVI-SGIGG 200 Query: 153 VGTAAIQLTRMAGAIPLVTAGSQKKLQMAEKLGAAAGFNYKK-EDFSEATLKFTKGAGVN 211 +G A+Q R G +KL +A +LGA N K D + K T G Sbjct: 201 LGHMAVQYARAMGLNVAAVDIDDRKLDLARRLGATVTVNAKTVADPAAYIRKETDGGAQG 260 Query: 212 LILDCIGGSYWEKNVNCLALDGRWVLYGLMGGGDINGPLFSKLLFKRGSLITSLLRSRDN 271 +++ + +E+ + +A G L GL GD +F+ +L ++ S++ +R + Sbjct: 261 VLVTAVSPKAFEQALGMVARGGTVSLNGLP-PGDFPLSIFNMVLN-GVTVRGSIVGTRLD 318 Query: 272 KYKQMLVNAFTEQILPHFSTEGPQRLLPVLDRIYPVTEIQEAHKYMEANKNIGKIVLELP 331 + + F+ +G + + + +I M G+IV++L Sbjct: 319 LQESL-----------DFAADGKVKATIQTGK---LEDINAIFDDMRQGNIEGRIVMDLT 364 Query: 332 Q 332 Q Sbjct: 365 Q 365 >5K1S-A nrPDB Length = 362 Score = 257 bits (656), Expect = 6e-69, Method: Composition-based stats. Identities = 95/360 (26%), Positives = 156/360 (43%), Gaps = 44/360 (12%) Query: 1 MLAVHFDKPGGPENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNI 60 M AV G NL ++ + P PG GEVLL+V A + D++ R+G P I Sbjct: 18 MKAVVLRSFGEAGNLKMETMPMPRPGRGEVLLRVHACGVCYHDVINRRGNL-PRTSVPAI 76 Query: 61 LGLEASGHVAELGPGCQGHWKIGDTAMALLP----------------------------G 92 LG EA+G V E+GP G WK GD A L Sbjct: 77 LGHEAAGEVIEVGPDTPG-WKTGDRAATLQRMSCGDCALCRSGRNSLCKTDNRFFGEELP 135 Query: 93 GGQAQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSG 152 GG AQ++ P G L +P L +AA + TA + G V+AG+ VLI G Sbjct: 136 GGYAQFMVAPVGGLGRVPASLPWNEAATVCCTTGTAVHTVRTRGKVRAGETVLITGASGG 195 Query: 153 VGTAAIQLTRMAGAIPLVTAGSQKKLQMAEKLGAAAGFNYKKEDFSEATLKFTKGAGVNL 212 VG +++QL R+ GA + S+ K+Q ++ GA + DF+ K T+GAGV++ Sbjct: 196 VGLSSVQLARLDGARVIAVTSSEAKVQALKEAGADEVIVSRGLDFASDVRKRTQGAGVDV 255 Query: 213 ILDCIGGSYWEKNVNCLALDGRWVLYGLMGGGDINGPLFSKLLFKRGSLITSLLRSRDNK 272 ++ +G + +++ + +A GR V+ G + G + ++ K ++ + ++ Sbjct: 256 AVEIVGSATFDQTLKSMAPGGRVVVVGNLESGMVQ-LNPGLVIVKELEILGAYATTQAEL 314 Query: 273 YKQMLVNAFTEQILPHFSTEGPQRLLPVLDRIYPVTEIQEAHKYMEANKNIGKIVLELPQ 332 + + + P+ E +AH +E + G++VL P+ Sbjct: 315 DEA-------------LRLTATGGVRQFVTDAVPLAEAAKAHFRLENREVAGRLVLVPPE 361 >4Z6K-A nrPDB Length = 346 Score = 256 bits (654), Expect = 1e-68, Method: Composition-based stats. Identities = 82/357 (22%), Positives = 140/357 (39%), Gaps = 50/357 (14%) Query: 1 MLAVHFDKPGGPENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNI 60 M A + G ++L ++EV P+PG GE+++K+ AS + DL +G + P I Sbjct: 1 MKAAVLHEFG--QSLQIEEVDIPTPGAGEIVVKMQASGVCHTDLHAVEGDWPVKPSPPFI 58 Query: 61 LGLEASGHVAELGPGCQGHWKIGDTA----------------------------MALLPG 92 G E G + +G G H K GD Sbjct: 59 PGHEGVGLITAVGEGVT-HVKEGDRVGVAWLYSACGHCTHCLGGWETLCESQQNSGYSVN 117 Query: 93 GGQAQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSG 152 G A+YV + IPE + + A + A +T ++ L + + + GD+V+I +G+ G Sbjct: 118 GSFAEYVLANANYVGIIPESVDSIEIAPVLCAGVTVYKGLKMT-DTKPGDWVVI-SGIGG 175 Query: 153 VGTAAIQLTRMAGAIPLVTAGSQKKLQMAEKLGAAAGFNYKKEDFSEATLKFTKGAGVNL 212 +G A+Q G KL A+KLGA N K D +E K GA L Sbjct: 176 LGHMAVQYAIAMGLNVAAVDIDDDKLAFAKKLGAKVTVNAKNTDPAEYLQKEIGGAHGAL 235 Query: 213 ILDCIGGSYWEKNVNCLALDGRWVLYGLMGGGDINGPLFSKLLFKRGSLITSLLRSRDNK 272 + + +++ ++ L G V GL GD +F +L ++ S++ +R + Sbjct: 236 V-TAVSAKAFDQALSMLRRGGTLVCNGLP-PGDFPVSIFDTVLN-GITIRGSIVGTRLDL 292 Query: 273 YKQMLVNAFTEQILPHFSTEGPQRLLPVLDRIYPVTEIQEAHKYMEANKNIGKIVLE 329 + + + P+ I + + M K G+IV++ Sbjct: 293 QESL--------------DMAAAGKVKATVTAEPLENINDIFERMRQGKIEGRIVID 335 >6N7L-A nrPDB Length = 353 Score = 251 bits (640), Expect = 4e-67, Method: Composition-based stats. Identities = 83/356 (23%), Positives = 138/356 (38%), Gaps = 47/356 (13%) Query: 1 MLAVHFDKPGGPENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNI 60 M A G P L ++EV PG EVL+KV A + DL G + P I Sbjct: 14 MKAAVVQGYGEP--LKIQEVPVREPGRYEVLVKVMACGVCHTDLHAVDGDWPAKPKMPLI 71 Query: 61 LGLEASGHVAELGP-------------------GCQGHWKIGDTAM-------ALLPGGG 94 G E G V GP GC + G + GG Sbjct: 72 PGHEGVGIVVACGPDAMVKEGDAVGVPWLYSACGCCDYCITGWETLCEAQQNGGYSVDGG 131 Query: 95 QAQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVG 154 A+YV + + + + A I A +T ++ L + G++V I +G+ G+G Sbjct: 132 FAEYVIADSRYVGHLKSNVNFLEIAPILCAGVTVYKGLKET-ETKPGEWVAI-SGIGGLG 189 Query: 155 TAAIQLTRMAGAIPLVTAGSQKKLQMAEKLGAAAGFNYKKEDFSEATLKFTKGAGVNLIL 214 A+Q + G + KL++A+KLGA N K D K G ++ Sbjct: 190 HVAVQYAKAMGMHVAAIDVADDKLELAKKLGADLTVNAKTTDPGTYLHKEVGGMH-GALI 248 Query: 215 DCIGGSYWEKNVNCLALDGRWVLYGLMGGGDINGPLFSKLLFKRGSLITSLLRSRDNKYK 274 + +++ ++ L G L GL G P+F +L KR ++ S++ +R + + Sbjct: 249 TAVSPIAFKQGIDVLRRKGTIALNGLP-PGSFELPIFETVL-KRITVRGSIVGTRKDLQE 306 Query: 275 QMLVNAFTEQILPHFSTEGPQRLLPVLDRIYPVTEIQEAHKYMEANKNIGKIVLEL 330 + F+ EG L+ + +I + M+ + G+IVL++ Sbjct: 307 AL-----------DFANEG---LVKATVTSAKLEDINDVFDKMKKGQIDGRIVLDI 348 >5ENV-A nrPDB Length = 347 Score = 249 bits (637), Expect = 8e-67, Method: Composition-based stats. Identities = 82/358 (22%), Positives = 145/358 (40%), Gaps = 49/358 (13%) Query: 4 VHFDKPGGPENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNILGL 63 + ++ G L K++ P P E+L+ V S + DL G + P + G Sbjct: 10 IFYESHG---KLEYKDIPVPKPKANELLINVKYSGVCHTDLHAWHGDWPLPVKLPLVGGH 66 Query: 64 EASGHVAELGPGCQGHWKIGDTA----------------------------MALLPGGGQ 95 E +G V +G +G WKIGD A G Sbjct: 67 EGAGVVVGMGENVKG-WKIGDYAGIKWLNGSCMACEYCELGNESNCPHADLSGYTHDGSF 125 Query: 96 AQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGT 155 QY T IP+G L Q A I A +T ++ L N+ AG +V I G+G+ Sbjct: 126 QQYATADAVQAAHIPQGTDLAQVAPILCAGITVYKALK-SANLMAGHWVAISGAAGGLGS 184 Query: 156 AAIQLTRMAGAIPLVTAGSQKKLQMAEKLGAAAGFNYKKE-DFSEATLKFTKGAGVNLIL 214 A+Q + G L G + K ++ +G ++ KE D A LK T G +I Sbjct: 185 LAVQYAKAMGYRVLGIDGGEGKEELFRSIGGEVFIDFTKEKDIVGAVLKATDGGAHGVIN 244 Query: 215 DCIGGSYWEKNVNCLALDGRWVLYGLMGGGDINGPLFSKLLFKRGSLITSLLRSRDNKYK 274 + + E + + +G VL G+ G +F++++ K S++ S + +R + Sbjct: 245 VSVSEAAIEASTRYVRANGTTVLVGMPAGAKCCSDVFNQVV-KSISIVGSYVGNRAD--- 300 Query: 275 QMLVNAFTEQILPHFSTEGPQRLLPVLDRIYPVTEIQEAHKYMEANKNIGKIVLELPQ 332 T + L F+ + L+ ++ ++ + E ++ ME + +G+ V++ + Sbjct: 301 -------TREALDFFA----RGLVKSPIKVVGLSTLPEIYEKMEKGQIVGRYVVDTSK 347 >3JYN-A nrPDB Length = 325 Score = 249 bits (636), Expect = 1e-66, Method: Composition-based stats. Identities = 83/328 (25%), Positives = 137/328 (41%), Gaps = 8/328 (2%) Query: 2 LAVHFDKPGGPENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNIL 61 + F GGPE L + +PG V+++ A LN D R G Y P P + L Sbjct: 3 KRIQFSTVGGPEVLEYVDFEPEAPGPQAVVVRNKAIGLNFIDTYYRSGLY-PAPFLPSGL 61 Query: 62 GLEASGHVAELGPGCQGHWKIGDTA-MALLPGGGQAQYVTVPEGLLMPIPEGLTLTQAAA 120 G E +G V +G +K+GD P G ++ +PE L+ + + ++ QAAA Sbjct: 62 GAEGAGVVEAVGDEVT-RFKVGDRVAYGTGPLGAYSEVHVLPEANLVKLADSVSFEQAAA 120 Query: 121 IPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQM 180 + LT LL V+ G+ +L HA GVG+ A Q + GA + T S +K Sbjct: 121 LMLKGLTVQYLLRQTYQVKPGEIILFHAAAGGVGSLACQWAKALGAKLIGTVSSPEKAAH 180 Query: 181 AEKLGAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIGGSYWEKNVNCLALDGRWVLYGL 240 A+ LGA +Y ED ++ L+ T G ++ D +G W +++ +A G V +G Sbjct: 181 AKALGAWETIDYSHEDVAKRVLELTDGKKCPVVYDGVGQDTWLTSLDSVAPRGLVVSFGN 240 Query: 241 MGGGDINGPLFSKLLFKRGSLITSLLRSRDNKYKQMLVNAFTEQILPHFSTEGPQRLLPV 300 G ++G +L ++ S+ + F +L Sbjct: 241 ASG-PVSGVNLG-ILAQKDSVYVTRP---TLGSYANNAQNLQTMADELFDMLASGKLKVD 295 Query: 301 LDRIYPVTEIQEAHKYMEANKNIGKIVL 328 Y + + +A + A + G +L Sbjct: 296 GIEQYALKDAAKAQIELSARRTTGSTIL 323 >2WEK-A nrPDB Length = 341 Score = 248 bits (633), Expect = 2e-66, Method: Composition-based stats. Identities = 89/323 (27%), Positives = 142/323 (43%), Gaps = 12/323 (3%) Query: 18 KEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNILGLEASGHVAELGPGCQ 77 ++ P PG+G++L++ +N +D+ G+YDP +G E G V LG Sbjct: 23 RDCPVPLPGDGDLLVRNRFVGVNASDINYSAGRYDPSVKPPFDIGFEGIGEVVALGLSAS 82 Query: 78 GHWKIGDTAMALLPGGGQAQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGN 137 + +G A+A + G A+Y VP + P+P + + + TA+ L +G Sbjct: 83 ARYTVG-QAVAYMAPGSFAEYTVVPASIATPVPSVKP--EYLTLLVSGTTAYISLKELGG 139 Query: 138 VQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQMAEKLGAAAGFNYKKEDF 197 + G VL+ A G G A+QL++ A + T S +K + LG NYK E Sbjct: 140 LSEGKKVLVTAAAGGTGQFAMQLSKKAKCHVIGTCSSDEKSAFLKSLGCDRPINYKTE-P 198 Query: 198 SEATLKFTKGAGVNLILDCIGGSYWEKNVNCLALDGRWVLYGLMGGGDIN--------GP 249 LK GV+++ + +GG+ ++ V+ LA GR ++ G + G G Sbjct: 199 VGTVLKQEYPEGVDVVYESVGGAMFDLAVDALATKGRLIVIGFISGYQTPTGLSPVKAGT 258 Query: 250 LFSKLLFKRGSLITSLLRSRDNKYKQMLVNAFTEQILPHFSTEGPQRLLPVLDRIYPVTE 309 L +KLL K S+ L +KY+ + + + E L R + Sbjct: 259 LPAKLLKKSASVQGFFLNHYLSKYQAAMSHLLEMCVSGDLVCEVDLGDLSPEGRFTGLES 318 Query: 310 IQEAHKYMEANKNIGKIVLELPQ 332 I A YM KN GKIV+ELP Sbjct: 319 IFRAVNYMYMGKNTGKIVVELPH 341 >3S2F-A nrPDB Length = 340 Score = 248 bits (632), Expect = 3e-66, Method: Composition-based stats. Identities = 79/360 (21%), Positives = 138/360 (38%), Gaps = 50/360 (13%) Query: 1 MLAVHFDKPGGPENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNI 60 M A G P L + EV P PG G+V +K+ AS + DL G + P I Sbjct: 3 MKAAVVRAFGAP--LTIDEVPVPQPGPGQVQVKIEASGVCHTDLHAADGDWPVKPTLPFI 60 Query: 61 LGLEASGHVAELGPGCQGHWKIGDTA----------------------------MALLPG 92 G E G+V+ +G G K GD Sbjct: 61 PGHEGVGYVSAVGSGVS-RVKEGDRVGVPWLYSACGYCEHCLQGWETLCEKQQNTGYSVN 119 Query: 93 GGQAQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSG 152 GG +YV + +P+ + + A I A +T ++ L V + + G +V+I +G+ G Sbjct: 120 GGYGEYVVADPNYVGLLPDKVGFVEIAPILCAGVTVYKGLK-VTDTRPGQWVVI-SGIGG 177 Query: 153 VGTAAIQLTRMAGAIPLVTAGSQKKLQMAEKLGAAAGFNYKKEDFSEATLKFTKGAGVNL 212 +G A+Q R G KL +A +LGA N + D + K GA + Sbjct: 178 LGHVAVQYARAMGLRVAAVDIDDAKLNLARRLGAEVAVNARDTDPAAWLQKEIGGAH-GV 236 Query: 213 ILDCIGGSYWEKNVNCLALDGRWVLYGLMGGGDINGPLFSKLLFKRGSLITSLLRSRDNK 272 ++ + + + + + G L GL GD P+F +L K ++ S++ +R + Sbjct: 237 LVTAVSPKAFSQAIGMVRRGGTIALNGLP-PGDFGTPIFDVVL-KGITIRGSIVGTRSDL 294 Query: 273 YKQMLVNAFTEQILPHFSTEGPQRLLPVLDRIYPVTEIQEAHKYMEANKNIGKIVLELPQ 332 + + F+ G + + ++ + + K G++VL+ + Sbjct: 295 QESL-----------DFAAHGDVK---ATVSTAKLDDVNDVFGRLREGKVEGRVVLDFSR 340 >2EER-A nrPDB Length = 347 Score = 246 bits (627), Expect = 1e-65, Method: Composition-based stats. Identities = 76/364 (20%), Positives = 147/364 (40%), Gaps = 55/364 (15%) Query: 1 MLAVHFDKPGGPENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPP----- 55 M A+ + G P L ++++ P P +VL+K+ A+ + +D+ RQG++ Sbjct: 1 MRAMRLVEIGKP--LKLEDIPIPKPKGSQVLIKIEAAGVCHSDVHMRQGRFGNLRIVEDL 58 Query: 56 --GASNILGLEASGHVAELGPGCQGH-------------------WKIGDTAMALLP--- 91 LG E +G + E+G G+ +IG+ + P Sbjct: 59 GVKLPVTLGHEIAGRIEEVGDEVVGYSKGDLVAVNPWEGEGNCYYCRIGEEHLCDSPRWL 118 Query: 92 ----GGGQAQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIH 147 G A+YV VP + L+ +AA + + +T ++ + ++ +++ Sbjct: 119 GINYDGAYAEYVLVPHYKYLYKLRRLSAVEAAPLTCSGVTTYRAVRK-ASLDPSKTLVVI 177 Query: 148 AGLSGVGTAAIQLTRM-AGAIPLVTAGSQKKLQMAEKLGAAAGFNYKKEDFSEATLKFTK 206 G+GT AIQ+ + +GA + ++ L+ A++ GA N +D + T+ Sbjct: 178 GAGGGLGTMAIQIAKAVSGATIIGVDVREEALEAAKRAGADYVINASSQDPVSEIRRITQ 237 Query: 207 GAGVNLILD-CIGGSYWEKNVNCLALDGRWVLYGLMGGG-DINGPLFSKLLFKRGSLITS 264 G G + ++D LA G++V+ GL G + PL + I S Sbjct: 238 GKGADAVIDLNNSEKTLSIYPYVLAKQGKYVMVGLFGADLKYHAPL---ITLNEVQFIGS 294 Query: 265 LLRSRDNKYKQMLVNAFTEQILPHFSTEGPQRLLPVLDRIYPVTEIQEAHKYMEANKNIG 324 L+ ++ + L S ++ P++ + + E EA +E K +G Sbjct: 295 LVGNQSD-------------FLGIMSLAEAGKVKPMVTKTMKLEEANEAIDNLENFKAVG 341 Query: 325 KIVL 328 + VL Sbjct: 342 RQVL 345 >3TQH-A nrPDB Length = 321 Score = 245 bits (625), Expect = 2e-65, Method: Composition-based stats. Identities = 97/338 (28%), Positives = 151/338 (44%), Gaps = 32/338 (9%) Query: 1 MLAVHFDKPGGPENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQG----QYDPPPG 56 M A+ FD+ G P+ L + + P + ++L+KV A++LN D R G Sbjct: 7 MKAIQFDQFGPPKVLKLVDTPTPEYRKNQMLIKVHAASLNPIDYKTRNGSGFVAKKLKNN 66 Query: 57 ASNILGLEASGHVAELGPGCQGHWKIGDTAMAL----LPGGGQAQYVTVPEGLLMPIPEG 112 + LG + SG V ELG + IGD M + A+YV ++ E Sbjct: 67 LPSGLGYDFSGEVIELGSDVN-NVNIGDKVMGIAGFPDHPCCYAEYVCASPDTIIQKLEK 125 Query: 113 LTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTA 172 L+ QAA++P A LTA Q L+ V+ GD VLIHAG GVG AIQL + G + TA Sbjct: 126 LSFLQAASLPTAGLTALQALNQ-AEVKQGDVVLIHAGAGGVGHLAIQLAKQKGTTVITTA 184 Query: 173 GSQKKLQMAEKLGAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIGGSYWEKNVNCLALD 232 S++ + LGA NY +EDF A V+ ++D +GG ++++CL Sbjct: 185 -SKRNHAFLKALGAEQCINYHEEDFLLAI-----STPVDAVIDLVGGDVGIQSIDCLKET 238 Query: 233 GRWVLYGLMGGGDINGPLFSKLLFKRGSLITSLLRSRDNKYKQMLVNAFTEQILPHFSTE 292 G V + G + +K +R + + Y LV+ Sbjct: 239 GCIVSVPTITAGRV--IEVAKQKHRRAFGLLKQFNIEELHYLGKLVS------------- 283 Query: 293 GPQRLLPVLDRIYPVTEIQEAHKYMEANKNIGKIVLEL 330 +L + RI+ ++E AH+ +E GK+V ++ Sbjct: 284 -EDKLRIEISRIFQLSEAVTAHELLETGHVRGKLVFKV 320 >5YAT-A nrPDB Length = 350 Score = 241 bits (616), Expect = 3e-64, Method: Composition-based stats. Identities = 82/360 (22%), Positives = 139/360 (38%), Gaps = 48/360 (13%) Query: 2 LAVHFDKPGGPENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNIL 61 AV F+ GGP L K++ P P E+L+ V S + DL +G + + Sbjct: 10 KAVIFETNGGP--LEYKDIPVPKPKSNELLINVKYSGVCHTDLHAWKGDWPLDNKLPLVG 67 Query: 62 GLEASGHVAELGPGCQGHWKIGDTA----------------------------MALLPGG 93 G E +G V G G W+IGD A G Sbjct: 68 GHEGAGVVVAYGENVTG-WEIGDYAGIKWLNGSCLNCEYCIQGAESSCAKADLSGFTHDG 126 Query: 94 GQAQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGV 153 QY T IP+ L + A I A +T ++ L +++ G +V I G+ Sbjct: 127 SFQQYATADATQAARIPKEADLAEVAPILCAGITVYKALK-TADLRIGQWVAISGAGGGL 185 Query: 154 GTAAIQLTRMAGAIPLVTAGSQKKLQMAEKLGAAAGFNY-KKEDFSEATLKFTKGAGVNL 212 G+ A+Q + G L G K + + LGA ++ K +D K T G + Sbjct: 186 GSLAVQYAKALGLRVLGIDGGADKGEFVKSLGAEVFVDFTKTKDVVAEVQKLTNGGPHGV 245 Query: 213 ILDCIGGSYWEKNVNCLALDGRWVLYGLMGGGDINGPLFSKLLFKRGSLITSLLRSRDNK 272 I + ++V + G+ VL GL G +N +F +L K + S + +R++ Sbjct: 246 INVSVSPHAINQSVQYVRTLGKVVLVGLPSGAVVNSDVFWHVL-KSIEIKGSYVGNREDS 304 Query: 273 YKQMLVNAFTEQILPHFSTEGPQRLLPVLDRIYPVTEIQEAHKYMEANKNIGKIVLELPQ 332 + + L+ +I ++E+ + ++ MEA IG+ V++ + Sbjct: 305 AEA--------------IDLFTRGLVKAPIKIIGLSELAKVYEQMEAGAIIGRYVVDTSK 350 >3UOG-A nrPDB Length = 363 Score = 230 bits (586), Expect = 7e-61, Method: Composition-based stats. Identities = 90/343 (26%), Positives = 155/343 (45%), Gaps = 41/343 (11%) Query: 12 PENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNILGLEASGHVAE 71 P +L + E P GE +++++ A +LN D + + + + SG V Sbjct: 38 PHDLKLAERPVPEAGEHDIIVRTLAVSLNYRDKLVLETGMGLDLAFPFVPASDMSGVVEA 97 Query: 72 LGPGCQGHWKIGDTAMALLPGG------------------------GQAQYVTVPEGLLM 107 +G ++ GD ++ G ++YV +PEG + Sbjct: 98 VGKSVT-RFRPGDRVISTFAPGWLDGLRPGTGRTPAYETLGGAHPGVLSEYVVLPEGWFV 156 Query: 108 PIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAI 167 P+ L +A+ +P A LTA+ L G+++AGD V++ G GV +Q+ + GA Sbjct: 157 AAPKSLDAAEASTLPCAGLTAWFALVEKGHLRAGDRVVVQ-GTGGVALFGLQIAKATGAE 215 Query: 168 PLVTAGSQKKLQMAEKLGAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIGGSYWEKNVN 227 +VT+ S++KL A LGA G N +ED+ E T G + IL+ GG+ +++ Sbjct: 216 VIVTSSSREKLDRAFALGADHGINRLEEDWVERVYALTGDRGADHILEIAGGAGLGQSLK 275 Query: 228 CLALDGRWVLYGLMGGGDINGPLFSKLLFKRGSLITSLLRSRDNKYKQMLVNAFTEQILP 287 +A DGR + G++ G +++GP+ LL K + + R + + LV A Sbjct: 276 AVAPDGRISVIGVLEGFEVSGPV-GPLLLKSPVVQGISVGHR--RALEDLVGAVDR---- 328 Query: 288 HFSTEGPQRLLPVLDRIYPVTEIQEAHKYMEANKNIGKIVLEL 330 L PV+D Y TE+ EA +++ GK+V+E Sbjct: 329 -------LGLKPVIDMRYKFTEVPEALAHLDRGP-FGKVVIEF 363 >4J6F-A nrPDB Length = 382 Score = 228 bits (581), Expect = 3e-60, Method: Composition-based stats. Identities = 95/363 (26%), Positives = 153/363 (42%), Gaps = 52/363 (14%) Query: 1 MLAVHFDKPGGPENLYV-KEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGA-- 57 M AV GG E L ++V P+P GEVL+KV A +N D+ R+G Y Sbjct: 34 MTAVLLTGHGGLEKLVYSRDVPVPAPAAGEVLIKVTACGMNNTDVWVREGAYGTEDDPSA 93 Query: 58 -------------SNILGLEASGHVAELGPGCQGHWKIGDTAMALLP------------- 91 I G + GH+ +G G +IG+ M Sbjct: 94 VSTWRRHGNTLTFPRIQGTDTVGHIVAVGEGV-DRARIGERVMVDFSIYNRDDDSLADID 152 Query: 92 ------GGGQAQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVL 145 GG A+Y+ +P + LT + A A+LT ++L + AG+ VL Sbjct: 153 YMGHGRDGGYAEYMALPAENAHVVATDLTDIELATFCCAYLTGERMLER-ARLAAGETVL 211 Query: 146 IHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQMAEKLGAAAGFNYKKEDFSEATLKFT 205 + GVG+A IQL R GA+P+ AG K+ M + +GA A + D +EA + Sbjct: 212 VTGASGGVGSAIIQLARARGAVPIAVAGPGKEAAMLD-IGAQAVVTRGQGDLAEAVEAAS 270 Query: 206 KGAGVNLILDCIGGSYWEKNVNCLALDGRWVLYGLMGGGDINGPLFSKLLFKRGSLITSL 265 G ++++ D +GG + + L +GR+ G + G + L + K+ L S Sbjct: 271 GGRPIDVVADLVGGPLFNDLLKILRPEGRYTTAGAIAGPVVQLDL-RTMYLKQLELHGSS 329 Query: 266 LRSRDNKYKQMLVNAFTEQILPHFSTEGPQRLLPVLDRIYPVTEIQEAHKYMEANKNIGK 325 SR + + LV E+ ++ P++ +YP++E A A +GK Sbjct: 330 QGSRADFRR--LVRYIEEK-----------KIRPLVGGVYPLSEFHRAQTDFMAKNFVGK 376 Query: 326 IVL 328 +V+ Sbjct: 377 LVV 379 >4EYE-A nrPDB Length = 342 Score = 226 bits (576), Expect = 1e-59, Method: Composition-based stats. Identities = 91/328 (27%), Positives = 148/328 (45%), Gaps = 9/328 (2%) Query: 1 MLAVHFDKPGGPENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNI 60 M A+ GPE L +V P G V++ V A+ + D + +G+Y + Sbjct: 22 MKAIQAQSLSGPEGLVYTDVETPGAGPNVVVVDVKAAGVCFPDYLMTKGEYQLKMEPPFV 81 Query: 61 LGLEASGHVAELGPGCQGHWKIGDTAMALLPGGGQAQYVTVPEGLLMPIPEGLTLTQAAA 120 G+E +G V G K GD MA GG A+ V V ++P P L +A A Sbjct: 82 PGIETAGVVRSAPEG--SGIKPGDRVMAFNFIGGYAERVAVAPSNILPTPPQLDDAEAVA 139 Query: 121 IPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQM 180 + + T + G ++AG+ VL+ G+GTAAIQ+ + GA + + Sbjct: 140 LIANYHTMYFAYARRGQLRAGETVLVLGAAGGIGTAAIQIAKGMGAKVIAVVNRTAATEF 199 Query: 181 AEKLGAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIGGSYWEKNVNCLALDGRWVLYGL 240 + +GA +E +++A + T GAGV++++D IGG ++ V LA +GR ++ G Sbjct: 200 VKSVGADIVL-PLEEGWAKAVREATGGAGVDMVVDPIGGPAFDDAVRTLASEGRLLVVGF 258 Query: 241 MGGGDINGPLFSKLLFKRGSLITSLLRSRDNKYKQMLVNAFTEQILPHFSTEGPQRLLPV 300 GG I ++LL + SLI + L T+ L EG + P Sbjct: 259 AAGG-IPTIKVNRLLLRNASLIGVAWGEFLRTHADYLYE--TQAGLEKLVAEGMR---PP 312 Query: 301 LDRIYPVTEIQEAHKYMEANKNIGKIVL 328 + P++E ++A + K GK+VL Sbjct: 313 VSARIPLSEGRQALQDFADGKVYGKMVL 340 >1R37-A nrPDB Length = 347 Score = 223 bits (568), Expect = 1e-58, Method: Composition-based stats. Identities = 78/364 (21%), Positives = 145/364 (39%), Gaps = 55/364 (15%) Query: 1 MLAVHFDKPGGPENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPP----- 55 M AV + G P L ++E+ P P +VL+KV A+ + +D+ RQG++ Sbjct: 1 MRAVRLVEIGKP--LSLQEIGVPKPKGPQVLIKVEAAGVCHSDVHMRQGRFGNLRIVEDL 58 Query: 56 --GASNILGLEASGHVAELGPGCQGH-------------------WKIGDTAMALLP--- 91 LG E +G + E+G G+ +IG+ + P Sbjct: 59 GVKLPVTLGHEIAGKIEEVGDEVVGYSKGDLVAVNPWQGEGNCYYCRIGEEHLCDSPRWL 118 Query: 92 ----GGGQAQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIH 147 G A+YV VP M L +AA + + +T ++ + ++ +L+ Sbjct: 119 GINFDGAYAEYVIVPHYKYMYKLRRLNAVEAAPLTCSGITTYRAVRK-ASLDPTKTLLVV 177 Query: 148 AGLSGVGTAAIQLTRM-AGAIPLVTAGSQKKLQMAEKLGAAAGFNYKKEDFSEATLKFTK 206 G+GT A+Q+ + +GA + ++ ++ A++ GA N +D + T+ Sbjct: 178 GAGGGLGTMAVQIAKAVSGATIIGVDVREEAVEAAKRAGADYVINASMQDPLAEIRRITE 237 Query: 207 GAGVNLILD-CIGGSYWEKNVNCLALDGRWVLYGLMGGG-DINGPLFSKLLFKRGSLITS 264 GV+ ++D LA G++V+ GL G + PL + + S Sbjct: 238 SKGVDAVIDLNNSEKTLSVYPKALAKQGKYVMVGLFGADLHYHAPL---ITLSEIQFVGS 294 Query: 265 LLRSRDNKYKQMLVNAFTEQILPHFSTEGPQRLLPVLDRIYPVTEIQEAHKYMEANKNIG 324 L+ ++ + L ++ P++ + + E EA +E K IG Sbjct: 295 LVGNQSD-------------FLGIMRLAEAGKVKPMITKTMKLEEANEAIDNLENFKAIG 341 Query: 325 KIVL 328 + VL Sbjct: 342 RQVL 345 >1H2B-A nrPDB Length = 359 Score = 213 bits (542), Expect = 8e-56, Method: Composition-based stats. Identities = 79/364 (21%), Positives = 156/364 (42%), Gaps = 58/364 (15%) Query: 1 MLAVHFDKPGGPENLYVKEVAKPSP-GEGEVLLKVAASALNRADLMQRQGQYD--PPPGA 57 + A + P L +++V P G +V++++A + + DL QG + P Sbjct: 16 LKAARLHEYNKP--LRIEDVDYPRLEGRFDVIVRIAGAGVCHTDLHLVQGMWHELLQPKL 73 Query: 58 SNILGLEASGHVAELGPGCQGHWKIGDTAM---------------------------ALL 90 LG E G++ E+ G +G + GD + L Sbjct: 74 PYTLGHENVGYIEEVAEGVEG-LEKGDPVILHPAVTDGTCLACRAGEDMHCENLEFPGLN 132 Query: 91 PGGGQAQYVTVPEGLLMPIPEGLT---LTQAAAIPEAWLTAFQLLHLVG-NVQAGDYVLI 146 GG A+++ ++ +P+ ++ L + A + +A +TA++ + + G YV I Sbjct: 133 IDGGFAEFMRTSHRSVIKLPKDISREKLVEMAPLADAGITAYRAVKKAARTLYPGAYVAI 192 Query: 147 HAGLSGVGTAAIQLTRMAG-AIPLVTAGSQKKLQMAEKLGAAAGFNYKKEDFSEATLKFT 205 G+ G+G A+QL ++ A + ++KL++AE+LGA + ++ D + ++ T Sbjct: 193 V-GVGGLGHIAVQLLKVMTPATVIALDVKEEKLKLAERLGADHVVDARR-DPVKQVMELT 250 Query: 206 KGAGVNLILDCIGG-SYWEKNVNCLALDGRWVLYGLMGGGDINGPLFSKLLFKRGSLITS 264 +G GVN+ +D +G + + L GR ++ G GG++ P +++ S S Sbjct: 251 RGRGVNVAMDFVGSQATVDYTPYLLGRMGRLIIVGY--GGELRFPTI-RVISSEVSFEGS 307 Query: 265 LLRSRDNKYKQMLVNAFTEQILPHFSTEGPQRLLPVLDRIYPVTEIQEAHKYMEANKNIG 324 L+ + L T Q + V I+ + EI + + +E + +G Sbjct: 308 LVGNYVE--------------LHELVTLALQGKVRVEVDIHKLDEINDVLERLEKGEVLG 353 Query: 325 KIVL 328 + VL Sbjct: 354 RAVL 357 >4EEZ-A nrPDB Length = 348 Score = 213 bits (542), Expect = 9e-56, Method: Composition-based stats. Identities = 79/360 (21%), Positives = 139/360 (38%), Gaps = 53/360 (14%) Query: 3 AVHFDKPGGPENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNILG 62 AV P G +L KE+ + E LL + + DL G + G +LG Sbjct: 4 AVVRHNPDGYADLVEKELR--AIKPNEALLDMEYCGVCHTDLHVAAGDFGNKAG--TVLG 59 Query: 63 LEASGHVAELGPGCQGHWKIGDTA----------------------------MALLPGGG 94 E G V E+G ++GD GG Sbjct: 60 HEGIGIVKEIGADVSS-LQVGDRVSVAWFFEGCGHCEYCVSGNETFCREVKNAGYSVDGG 118 Query: 95 QAQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVG 154 A+ V + +P+GL +A++I A +T ++ + + G V+ GD+ +I G G+G Sbjct: 119 MAEEAIVVADYAVKVPDGLDPIEASSITCAGVTTYKAIKVSG-VKPGDWQVIF-GAGGLG 176 Query: 155 TAAIQLTR-MAGAIPLVTAGSQKKLQMAEKLGAAAGFNYKKEDFSEATLKFTKGAGVNLI 213 AIQ + + GA + +Q KL +A+K+GA N + + K T G GV Sbjct: 177 NLAIQYAKNVFGAKVIAVDINQDKLNLAKKIGADVTINSGDVNPVDEIKKITGGLGVQSA 236 Query: 214 LDC-IGGSYWEKNVNCLALDGRWVLYGLMGGGDINGPLFSKLLFKRGSLITSLLRSRDNK 272 + C + +E+ V L G+ V + ++F + SL+ +R + Sbjct: 237 IVCAVARIAFEQAVASLKPMGKMVAVAVPNTEM--TLSVPTVVFDGVEVAGSLVGTRLDL 294 Query: 273 YKQMLVNAFTEQILPHFSTEGPQRLLPVLDRIYPVTEIQEAHKYMEANKNIGKIVLELPQ 332 + F ++ P++ + EI + M+A K G++V++ + Sbjct: 295 AEA-------------FQFGAEGKVKPIV-ATRKLEEINDIIDEMKAGKIEGRMVIDFTK 340 >3FBG-A nrPDB Length = 346 Score = 213 bits (541), Expect = 1e-55, Method: Composition-based stats. Identities = 81/362 (22%), Positives = 150/362 (41%), Gaps = 55/362 (15%) Query: 1 MLAVHFDKPGGPEN---LYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGA 57 + A+ F++P + + P P E+L+K+ + ++N D QR A Sbjct: 3 LKAIGFEQPFKLSDGNLFKTFNLDIPEPKVHEILVKIQSISVNPVDTKQRLMDVS---KA 59 Query: 58 SNILGLEASGHVAELGPGCQGHWKIGDTAM---ALLPGGGQAQYVTVPEGLLMPIPEGLT 114 +LG +A G V +G + GD + G A+Y + E L+ P+ ++ Sbjct: 60 PRVLGFDAIGVVESVGNEVT-MFNQGDIVYYSGSPDQNGSNAEYQLINERLVAKAPKNIS 118 Query: 115 LTQAAAIPEAWLTAFQLLHLVGNV------QAGDYVLIHAGLSGVGTAAIQLTRMAGAIP 168 QA ++P +TA++ L V + G +LI G GVG+ A Q+ + G Sbjct: 119 AEQAVSLPLTGITAYETLFDVFGISRNRNENEGKTLLIINGAGGVGSIATQIAKAYGLRV 178 Query: 169 LVTAGSQKKLQMAEKLGAAAGFNYKKEDFSEATLKFTKGAGVNLI--LDCIGGS--YWEK 224 + TA + ++ +K+GA N+K E+ L K G+ L+ + C + Y++ Sbjct: 179 ITTASRNETIEWTKKMGADIVLNHK-----ESLLNQFKTQGIELVDYVFCTFNTDMYYDD 233 Query: 225 NVNCLALDGRWV-LYGLMGGGDINGP-----------LFSKLLFKRGSLI--TSLLRSRD 270 + + G + D+N +F++ L + +I L Sbjct: 234 MIQLVKPRGHIATIVAFENDQDLNALKPKSLSFSHEFMFARPLNQTDDMIKHHEYLEDIT 293 Query: 271 NKYKQMLVNAFTEQILPHFSTEGPQRLLPVLDRIYPVTEIQEAHKYMEANKNIGKIVLEL 330 NK +Q + T +++ +TE I +AH+ +E+N IGK+V+ L Sbjct: 294 NKVEQNIYQPTTTKVIEGLTTEN----------------IYQAHQILESNTMIGKLVINL 337 Query: 331 PQ 332 + Sbjct: 338 NE 339 >2DFV-A nrPDB Length = 347 Score = 210 bits (534), Expect = 9e-55, Method: Composition-based stats. Identities = 93/366 (25%), Positives = 150/366 (40%), Gaps = 59/366 (16%) Query: 1 MLAVHFDKPGGPENLYVKEVAKPSPGEGEVLLKVAASALNRADLM------QRQGQYDPP 54 M+A+ KPG L EV P PG GEVL+KV A+++ DL Q + P Sbjct: 4 MVAIMKTKPGYGAEL--VEVDVPKPGPGEVLIKVLATSICGTDLHIYEWNEWAQSRIKP- 60 Query: 55 PGASNILGLEASGHVAELGPGCQGHWKIGDTA---------------------------M 87 I+G E +G V E+GPG +G ++GD Sbjct: 61 ---PQIMGHEVAGEVVEIGPGVEG-IEVGDYVSVETHIVCGKCYACRRGQYHVCQNTKIF 116 Query: 88 ALLPGGGQAQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIH 147 + G A+Y VP + P+ + + A + E A + L G + +G VLI Sbjct: 117 GVDTDGVFAEYAVVPAQNIWKNPKSIPP-EYATLQEPLGNAVDTV-LAGPI-SGKSVLIT 173 Query: 148 AGLSGVGTAAIQLTRMAGAIPLVTA-GSQKKLQMAEKLGAAAGFNYKKEDFSEATLKFTK 206 G +G I + + +GA P++ + S + ++A+K+GA N +ED + + T Sbjct: 174 -GAGPLGLLGIAVAKASGAYPVIVSEPSDFRRELAKKVGADYVINPFEEDVVKEVMDITD 232 Query: 207 GAGVNLILDCIG-GSYWEKNVNCLALDGRWVLYGLMGGGDINGPLFSKLLFKRGSLITSL 265 G GV++ L+ G E+ + + GR L GL G + + ++FK ++ Sbjct: 233 GNGVDVFLEFSGAPKALEQGLQAVTPAGRVSLLGLY-PGKVTIDFNNLIIFKALTIYGIT 291 Query: 266 LRSRDNKYKQMLVNAFTEQILPHFSTEGPQRLLPVLDRIYP-VTEIQEAHKYMEANKNIG 324 R T + G L P++ Y + +EA + M A K G Sbjct: 292 GRHLWE----------TWYTVSRLLQSGKLNLDPIITHKYKGFDKYEEAFELMRAGKT-G 340 Query: 325 KIVLEL 330 K+V L Sbjct: 341 KVVFML 346 >2VCY-A nrPDB Length = 344 Score = 209 bits (533), Expect = 1e-54, Method: Composition-based stats. Identities = 79/338 (23%), Positives = 130/338 (38%), Gaps = 15/338 (4%) Query: 1 MLAVHFDKPGGP-ENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASN 59 + A+ + G P + + +K + + +V +K+ A+ +N +D+ QG Y P Sbjct: 14 VRALVYGHHGDPAKVVELKNLELAAVRGSDVRVKMLAAPINPSDINMIQGNYGLLPELPA 73 Query: 60 ILGLEASGHVAELGPGCQGHWKIGDTAMALLPG-GGQAQYVTVPEGLLMPIPEGLTLTQA 118 + G E V +G G K GD + G G E L+ +P + L A Sbjct: 74 VGGNEGVAQVVAVGSNVTG-LKPGDWVIPANAGLGTWRTEAVFSEEALIQVPSDIPLQSA 132 Query: 119 AAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKL 178 A + TA+++L +Q GD V+ +A SGVG A IQ+ G + + + Sbjct: 133 ATLGVNPCTAYRMLMDFEQLQPGDSVIQNASNSGVGQAVIQIAAALGLRTINVVRDRPDI 192 Query: 179 ----QMAEKLGAAAGFNYKKEDFSEATLK--FTKGAGVNLILDCIGGSYWEKNVNCLALD 232 + LGA +E+ +K F L L+C+GG + + LA Sbjct: 193 QKLSDRLKSLGAEHVI--TEEELRRPEMKNFFKDMPQPRLALNCVGGKSSTELLRQLARG 250 Query: 233 GRWVLYGLMGGGDINGPLFSKLLFKRGSLITSLLRSRDNKYKQMLVNAFTEQILPHFSTE 292 G V YG M + + S L+FK L L + + F E IL Sbjct: 251 GTMVTYGGMAKQPVVASV-SLLIFKDLKLRGFWLSQWKKDHS---PDQFKELILTLCDLI 306 Query: 293 GPQRLLPVLDRIYPVTEIQEAHKYMEANKNIGKIVLEL 330 +L P+ + Q A + K +L + Sbjct: 307 RRGQLTAPACSQVPLQDYQSALEASMKPFISSKQILTM 344 >3SLK-A nrPDB Length = 795 Score = 209 bits (532), Expect = 1e-54, Method: Composition-based stats. Identities = 86/331 (25%), Positives = 146/331 (44%), Gaps = 28/331 (8%) Query: 7 DKPGGPENLYVKEVAKP--SPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNILGLE 64 +PG + L + + G+GEV + + A+ +N D + G Y LG E Sbjct: 216 TRPGSLDGLALVDEPTATAPLGDGEVRIAMRAAGVNFRDALIALGMYPGVAS----LGSE 271 Query: 65 ASGHVAELGPGCQGHWKIGDTAMALLPGGGQAQYVTVPEGLLMPIPEGLTLTQAAAIPEA 124 +G V E GPG G GD M ++P ++ IP G + +AA++P Sbjct: 272 GAGVVVETGPGVTG-LAPGDRVMGMIPK-AFGPLAVADHRMVTRIPAGWSFARAASVPIV 329 Query: 125 WLTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQMAEKL 184 +LTA+ L + ++ G+ +L+H+ GVG AAIQL R GA TA S+ K Q +L Sbjct: 330 FLTAYYALVDLAGLRPGESLLVHSAAGGVGMAAIQLARHLGAEVYATA-SEDKWQAV-EL 387 Query: 185 GAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIGGSYWEKNVNCLALDGRWVLYGLMGGG 244 + + DF + L T G GV+++L+ + G + + ++ L GR++ G Sbjct: 388 SREHLASSRTCDFEQQFLGATGGRGVDVVLNSLAGEFADASLRMLPRGGRFLELG---KT 444 Query: 245 DINGPLFSKLLFKRGSLI----TSLLRSRDNKYKQMLVNAFTEQILPHFSTEGPQRLLPV 300 D+ P+ S R + LV F ++L P+ Sbjct: 445 DVRDPVEVADAHPGVSYQAFDTVEAGPQRIGEMLHELVELFEGRVLE-----------PL 493 Query: 301 LDRIYPVTEIQEAHKYMEANKNIGKIVLELP 331 + V + EA +++ +++GK+VL +P Sbjct: 494 PVTAWDVRQAPEALRHLSQARHVGKLVLTMP 524 >4DVJ-A nrPDB Length = 363 Score = 206 bits (525), Expect = 1e-53, Method: Composition-based stats. Identities = 80/346 (23%), Positives = 146/346 (42%), Gaps = 28/346 (8%) Query: 1 MLAVHFDKPG---GPENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGA 57 M AV ++KP +L E+ KP+P ++L++V A ++N D R+ P Sbjct: 23 MKAVGYNKPAPITDDASLLDIELPKPAPAGHDILVEVKAVSVNPVDYKVRRST-PPDGTD 81 Query: 58 SNILGLEASGHVAELGPGCQGHWKIGDTAM---ALLPGGGQAQYVTVPEGLLMPIPEGLT 114 ++G +A+G V+ +GP ++ GD +++ G A++ V E ++ P+ L Sbjct: 82 WKVIGYDAAGIVSAVGPDVT-LFRPGDEVFYAGSIIRPGTNAEFHLVDERIVGRKPKTLD 140 Query: 115 LTQAAAIPEAWLTAFQLLHLVGNVQ-----AGDYVLIHAGLSGVGTAAIQLTRMA-GAIP 168 +AAA+P +TA++ +V A +LI G GVG+ A+Q+ R Sbjct: 141 WAEAAALPLTSITAWEAFFDRLDVNKPVPGAAPAILIVGGAGGVGSIAVQIARQRTDLTV 200 Query: 169 LVTAGSQKKLQMAEKLGAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIGGSYWEKNVNC 228 + TA + + + LGA ++ K + GA + + + + Sbjct: 201 IATASRPETQEWVKSLGAHHVIDHSKP-LAAEVAALGLGAPAFVFSTTHTDKHAAEIADL 259 Query: 229 LALDGRWVLYGLMGGGDINGPLFSKLLFKRG--SLITSLLRSRDNKYKQMLVN-AFTEQI 285 +A GR+ L F +LFKR S+ L+ +R + Sbjct: 260 IAPQGRFCLIDDPSA-------FDIMLFKRKAVSIHHELMFTRPMFGTPDMSEQGRLLND 312 Query: 286 LPHFSTEGPQRLLPVLDRIYPVTEIQ--EAHKYMEANKNIGKIVLE 329 + EG R + +R+ P+ +AH +E+ GK+V+E Sbjct: 313 VSRLVDEGRLRTT-LTNRLSPINAANLKQAHALVESGTARGKVVIE 357 >3GFB-A nrPDB Length = 350 Score = 202 bits (515), Expect = 1e-52, Method: Composition-based stats. Identities = 91/364 (25%), Positives = 144/364 (39%), Gaps = 59/364 (16%) Query: 1 MLAVHFDKPGGPENLYVKEVAKPSPGEGEVLLKVAASALNRADLM------QRQGQYDPP 54 M A+ KP L EV P PG GEVL+KV A+++ DL Q + P Sbjct: 5 MQAIMKTKPAYGAEL--VEVDVPKPGPGEVLIKVLATSICGTDLHIYEWNEWAQSRIKP- 61 Query: 55 PGASNILGLEASGHVAELGPGCQGHWKIGD---------------------------TAM 87 I+G E +G V E+GPG + ++GD Sbjct: 62 ---PQIMGHEVAGEVVEVGPGVE-DLQVGDYISVETHIVCGKCYACKHNRYHVCQNTKIF 117 Query: 88 ALLPGGGQAQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIH 147 + G A Y VP P+ + + AA+ E A + L G + AG LI Sbjct: 118 GVDMDGVFAHYAIVPAKNAWKNPKDMPP-EYAALQEPLGNAVDTV-LAGPI-AGRSTLIT 174 Query: 148 AGLSGVGTAAIQLTRMAGAIPLVTA-GSQKKLQMAEKLGAAAGFNYKKEDFSEATLKFTK 206 G +G I + + +GA P++ + S+ + ++A+K+GA N +ED + + T Sbjct: 175 -GAGPLGLLGIAVAKASGAYPVIVSEPSEFRRKLAKKVGADYVVNPFEEDPVKFVMDITD 233 Query: 207 GAGVNLILDCIG-GSYWEKNVNCLALDGRWVLYGLMGGGDINGPLFSKLLFKRGSLITSL 265 GAGV + L+ G E+ + + GR L GL ++ + ++FK + Sbjct: 234 GAGVEVFLEFSGAPKALEQGLKAVTPGGRVSLLGLF-PREVTIDFNNLIIFKALEVHGIT 292 Query: 266 LRSRDNKYKQMLVNAFTEQILPHFSTEGPQRLLPVLDRIYP-VTEIQEAHKYMEANKNIG 324 R T + G L P++ Y + +EA + M A K G Sbjct: 293 GRHLWE----------TWYTVSSLIQSGKLNLDPIITHKYKGFDKFEEAFELMRAGKT-G 341 Query: 325 KIVL 328 K+V Sbjct: 342 KVVF 345 >2VN8-A nrPDB Length = 375 Score = 202 bits (514), Expect = 2e-52, Method: Composition-based stats. Identities = 89/357 (24%), Positives = 145/357 (40%), Gaps = 33/357 (9%) Query: 2 LAVHFDKPGGPENLYVKE-VAKPSPG-EGEVLLKVAASALNRADLMQRQG--------QY 51 +A DK G E L + + P EV++KV A+++N D+ R G + Sbjct: 23 MAWVIDKYGKNEVLRFTQNMMMPIIHYPNEVIVKVHAASVNPIDVNMRSGYGATALNMKR 82 Query: 52 DPPP------GASNILGLEASGHVAELGPGCQGHWKIGDTAMALLPG---GGQAQYVTVP 102 DP LG + SG V E G + ++K GD A +P G +++V V Sbjct: 83 DPLHVKIKGEEFPLTLGRDVSGVVMECGLDVK-YFKPGDEVWAAVPPWKQGTLSEFVVVS 141 Query: 103 EGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQ----AGDYVLIHAGLSGVGTAAI 158 + P+ LT TQAA++P LTA+ ++ VG + G VLI GVGT AI Sbjct: 142 GNEVSHKPKSLTHTQAASLPYVALTAWSAINKVGGLNDKNCTGKRVLILGASGGVGTFAI 201 Query: 159 QLTRMAGAIPLVTAGSQKKLQMAEKLGAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIG 218 Q+ + A SQ ++ KLGA +YK E + ILD +G Sbjct: 202 QVMKAWDAHVTAVC-SQDASELVRKLGADDVIDYKSGSVEEQLKSL---KPFDFILDNVG 257 Query: 219 GSYWEKNVNCLAL--DGRWVLYGLMGGGDINGPLFSKLLFKRGSLITSLLRSRDNK---Y 273 GS + L +V +++ + + + G + S K Y Sbjct: 258 GSTETWAPDFLKKWSGATYVTLVTPFLLNMDRLGIADGMLQTGVTVGSKALKHFWKGVHY 317 Query: 274 KQMLVNAFTEQILPHFSTEGPQRLLPVLDRIYPVTEIQEAHKYMEANKNIGKIVLEL 330 + A + ++ PV+++ +P +++ EA +E GK V+ + Sbjct: 318 RWAFFMASGPCLDDIAELVDAGKIRPVIEQTFPFSKVPEAFLKVERGHARGKTVINV 374 >5A3V-A nrPDB Length = 329 Score = 202 bits (513), Expect = 2e-52, Method: Composition-based stats. Identities = 88/341 (25%), Positives = 153/341 (44%), Gaps = 28/341 (8%) Query: 1 MLAVHFDKPGG-PENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDP--PPGA 57 M A+ ++ GG L +V P+P EV LK+ A++LN D ++G P P Sbjct: 6 MHALQYNSYGGGAAGLEHVQVPVPTPKSNEVCLKLEATSLNPVDWKIQKGMIRPFLPRKF 65 Query: 58 SNILGLEASGHVAELGPGCQGHWKIGDTAMALLP---GGGQAQYVTVPEGLLMPIPEGLT 114 I + +G V E+G G + ++K GD +A+L GGG A++ E L + P+ + Sbjct: 66 PCIPATDVAGEVVEVGSGVK-NFKAGDKVVAVLSHLGGGGLAEFAVATEKLTVKRPQEVG 124 Query: 115 LTQAAAIPEAWLTAFQLLHLVGNVQAGDY-----VLIHAGLSGVGTAAIQLTRMAGAIPL 169 +AAA+P A LTA Q L ++ +L+ A GVG A+QL ++A A Sbjct: 125 AAEAAALPVAGLTALQALTNPAGLKLDGTGKKANILVTAASGGVGHYAVQLAKLANAHVT 184 Query: 170 VTAGSQKKLQMAEKLGAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIGGSYWEKNVNCL 229 T G++ ++ + LGA +YK + A LK G + ++ C G + L Sbjct: 185 ATCGAR-NIEFVKSLGADEVLDYKTPE--GAALKSPSGKKYDAVVHCANGIPFSVFEPNL 241 Query: 230 ALDGRWVLYGLMGGGDINGPLFSKLLFKRGSLITSLLRSRDNKYKQMLVNAFTEQILPHF 289 + +G+ + G + K+ + L+ LL + + +VN E Sbjct: 242 SENGKVIDI-TPGPNAMWTYAVKKITMSKKQLVPLLLIPKAEN-LEFMVNLVKE------ 293 Query: 290 STEGPQRLLPVLDRIYPVTEIQEAHKYMEANKNIGKIVLEL 330 ++ V+D +P+++ ++A GKI++E Sbjct: 294 -----GKVKTVIDSKHPLSKAEDAWAKSIDGHATGKIIVEP 329 >4GKV-A nrPDB Length = 336 Score = 199 bits (505), Expect = 2e-51, Method: Composition-based stats. Identities = 74/360 (20%), Positives = 135/360 (37%), Gaps = 52/360 (14%) Query: 1 MLAVHFDKPGGPENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNI 60 M A K ++ V S GE LLK+ + DL + G + G I Sbjct: 1 MKAAVVTK---DHHVDVTYKTLRSLKHGEALLKMECCGVCHTDLHVKNGDFGDKTGV--I 55 Query: 61 LGLEASGHVAELGPGCQGHWKIGDTA----------------------------MALLPG 92 LG E G VAE+GPG K GD A Sbjct: 56 LGHEGIGVVAEVGPGVTS-LKPGDRASVAWFYEGCGHCEYCNSGNETLCRSVKNAGYSVD 114 Query: 93 GGQAQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSG 152 GG A+ V + +P+GL A++I A +T ++ + L ++ G ++ I+ Sbjct: 115 GGMAEECIVVADYAVKVPDGLDSAAASSITCAGVTTYKAVKL-SKIRPGQWIAIYGLGGL 173 Query: 153 VGTAAIQLTRMAGAIPLVTAGSQKKLQMAEKLGAAAGFNYKKEDFSEATLKFTKGAGVNL 212 A + A + + ++L++A ++GA N ED ++ + T GA Sbjct: 174 GNLALQYAKNVFNAKVIAIDVNDEQLKLATEMGADLAINSHTEDAAKIVQEKTGGA-HAA 232 Query: 213 ILDCIGGSYWEKNVNCLALDGRWVLYGLMGGGDINGPLFSKLLFKRGSLITSLLRSRDNK 272 ++ + + + V+ + GR V GL + +L+ ++ SL+ +R + Sbjct: 233 VVTAVAKAAFNSAVDAVRAGGRVVAVGLPP--ESMSLDIPRLVLDGIEVVGSLVGTRQDL 290 Query: 273 YKQMLVNAFTEQILPHFSTEGPQRLLPVLDRIYPVTEIQEAHKYMEANKNIGKIVLELPQ 332 + F +++P + + P+ +I ME K G++V++ Sbjct: 291 TEA-------------FQFAAEGKVVPKV-ALRPLADINTIFTEMEEGKIRGRMVIDFRH 336 >3HZZ-A nrPDB Length = 467 Score = 191 bits (486), Expect = 3e-49, Method: Composition-based stats. Identities = 80/377 (21%), Positives = 131/377 (34%), Gaps = 78/377 (20%) Query: 13 ENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQ-------------RQGQYDPPPG--- 56 +++++ EV P G GE L+ V AS++N + R G+ P Sbjct: 74 KSIHLDEVPVPELGPGEALVAVMASSVNYNSVWTSIFEPVSTFAFLERYGKLSPLTKRHD 133 Query: 57 -ASNILGLEASGHVAELGPGCQGHWKIGDTAMA-----------------LLPG------ 92 +I+G + +G V GPG W+ GD +A L P Sbjct: 134 LPYHIIGSDLAGVVLRTGPGVNA-WQPGDEVVAHCLSVELESPDGHDDTMLDPEQRIWGF 192 Query: 93 ----GGQAQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLL--HLVGNVQAGDYVLI 146 GG A+ V LMP P+ LT +AAA TA++ L ++ GD VLI Sbjct: 193 ETNFGGLAEIALVKTNQLMPKPKHLTWEEAAAPGLVNSTAYRQLVSRNGAAMKQGDNVLI 252 Query: 147 HAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQMAEKLGAAAGFNYKKED---------- 196 G+G+ A Q GA P+ S +K ++ +GA A + E Sbjct: 253 WGASGGLGSYATQFALAGGANPICVVSSPQKAEICRSMGAEAIIDRNAEGYKFWKDEHTQ 312 Query: 197 -------FSEATLKFTKGAGVNLILDCIGGSYWEKNVNCLALDGRWVLYGLMGGGDINGP 249 F + + T G ++++ + G + +V G G Sbjct: 313 DPKEWKRFGKRIRELTGGEDIDIVFEHPGRETFGASVYVTRKGGTITTCASTSGYMHEYD 372 Query: 250 LFSKLLFKRGSLITSLLRSRDNKYKQMLVNAFTEQILPHFSTEGPQRLLPVLDRIYPVTE 309 L +I S + Y+ ++ P L + Y + E Sbjct: 373 N-RYLWMSLKRIIGSHFANYREAYEAN-------------RLIAKGKIHPTLSKTYSLEE 418 Query: 310 IQEAHKYMEANKNIGKI 326 +A + N + GK+ Sbjct: 419 TGQAAYDVHRNLHQGKV 435 >2H6E-A nrPDB Length = 344 Score = 189 bits (481), Expect = 1e-48, Method: Composition-based stats. Identities = 70/362 (19%), Positives = 128/362 (35%), Gaps = 55/362 (15%) Query: 2 LAVHFDKPGGPENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPP-GASNI 60 A K P L +++V P P EVL+++ + + R DL +G I Sbjct: 5 KAALLKKFSEP--LSIEDVNIPEPQGEEVLIRIGGAGVCRTDLRVWKGVEAKQGFRLPII 62 Query: 61 LGLEASGHVAELGPGCQGHWKIGDTAMAL---------------------------LPGG 93 LG E +G + E+G K GD + G Sbjct: 63 LGHENAGTIVEVGE--LAKVKKGDNVVVYATWGDLTCRYCREGKFNICKNQIIPGQTTNG 120 Query: 94 GQAQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGN--VQAGDYVLIHAGLS 151 G ++Y+ V + L+ +AA + +A T+ + + + V+I G+ Sbjct: 121 GFSEYMLVKSSRWLVKLNSLSPVEAAPLADAGTTSMGAIRQALPFISKFAEPVVIVNGIG 180 Query: 152 GVGTAAIQLTRMA--GAIPLVTAGSQKKLQMAEKLGAAAGFNYKKEDFSEATLKFTKGAG 209 G+ IQ+ + + + S+K A +LGA + +D K T G G Sbjct: 181 GLAVYTIQILKALMKNITIVGISRSKKHRDFALELGADYV--SEMKDAESLINKLTDGLG 238 Query: 210 VNLILDCIGGSYWEKNV-NCLALDGRWVLYGLMGGGDINGPLFSKLLFKRGSLITSLLRS 268 ++ +D +G N+ LA +G +L G+ G S F LL S Sbjct: 239 ASIAIDLVGTEETTYNLGKLLAQEGAIILVGMEGKR------VSLEAFDTAVWNKKLLGS 292 Query: 269 RDNKYKQMLVNAFTEQILPHFSTEGPQRLLPVLDRIYPVTEIQEAHKYMEANKNIGKIVL 328 + ++ P + ++ P+ +I +A ++ + G+ V+ Sbjct: 293 NYGS---------LNDLEDVVRLSESGKIKPYIIKV-PLDDINKAFTNLDEGRVDGRQVI 342 Query: 329 EL 330 Sbjct: 343 TP 344 >4A10-A nrPDB Length = 447 Score = 187 bits (476), Expect = 4e-48, Method: Composition-based stats. Identities = 82/379 (21%), Positives = 138/379 (36%), Gaps = 78/379 (20%) Query: 13 ENLYVKEVAKPSPGEGEVLLKVAASALNRADLM----------------QRQGQYDPPPG 56 ++L + EV P EVL+ V AS++N + RQG + Sbjct: 48 KSLRLGEVPMPELAPDEVLVAVMASSINYNTVWSAMFEPIPTFHFLKQNARQGGWATRHD 107 Query: 57 AS-NILGLEASGHVAELGPGCQGHWKIGDTAMAL-------------------------- 89 ++LG + SG V G G + WK GD + Sbjct: 108 QPYHVLGSDCSGVVVRTGIGVR-RWKPGDHVIVHPAHVDEQEPATHGDGMLGTEQRAWGF 166 Query: 90 -LPGGGQAQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLL--HLVGNVQAGDYVLI 146 GG A+Y V L+P P LT +AA P TA+++L ++ GD VLI Sbjct: 167 ETNFGGLAEYGVVRASQLLPKPAHLTWEEAAVSPLCAGTAYRMLVSDRGAQMKQGDIVLI 226 Query: 147 HAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQMAEKLGAAAGFNYKK----EDFSEATL 202 G+G+ AIQ + G IP+ S +K LG N + +D ++ Sbjct: 227 WGASGGLGSYAIQFVKNGGGIPVAVVSSAQKEAAVRALGCDLVINRAELGITDDIADDPR 286 Query: 203 KFTK-------------GAGVNLILDCIGGSYWEKNVNCLALDGRWVLYGLMGGGDINGP 249 + + G +++ + G + +V G V G G ++ Sbjct: 287 RVVETGRKLAKLVVEKAGREPDIVFEHTGRVTFGLSVIVARRGGTVVTCGSSSGY-LHTF 345 Query: 250 LFSKLLFKRGSLITSLLRSRDNKYKQMLVNAFTEQILPHFSTEGPQRLLPVLDRIYPVTE 309 L K ++ S N +Q N E ++P + +YP+ E Sbjct: 346 DNRYLWMKLKKIVGS---HGANHEEQQATNRLFE----------SGAVVPAMSAVYPLAE 392 Query: 310 IQEAHKYMEANKNIGKIVL 328 EA + ++ ++ +GK+ + Sbjct: 393 AAEACRVVQTSRQVGKVAV 411 >4IDE-A nrPDB Length = 332 Score = 183 bits (465), Expect = 8e-47, Method: Composition-based stats. Identities = 92/342 (26%), Positives = 150/342 (43%), Gaps = 52/342 (15%) Query: 2 LAVHFDKPGGPENLYVKE--VAKPSPGEGEVLLKVAASALNRADLMQRQGQY-DPPPGAS 58 A + + G ++ + VA P E +VL+KV A++LN D + G + D Sbjct: 25 KAWVYSEYGKTSDVLKFDPSVAVPEIKEDQVLIKVVAASLNPVDFKRALGYFKDTDSPLP 84 Query: 59 NILGLEASGHVAELGPGCQGHWKIGDTAMALLPG---------GGQAQYVTVPEGLLMPI 109 I G + +G V ++G +K+GD L G A+Y E +L Sbjct: 85 TIPGYDVAGVVVKVGSQVT-KFKVGDEVYGDLNETALVNPTRFGSLAEYTAADERVLAHK 143 Query: 110 PEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRM-AGAIP 168 P+ L+ +AA++P A TA + L + AG VL+ G GVGT IQL + GA Sbjct: 144 PKNLSFIEAASLPLAIETAHEGLER-AELSAGKSVLVLGGAGGVGTHIIQLAKHVFGASK 202 Query: 169 LVTAGSQKKLQMAEKLGAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIGGSYWEKNVNC 228 + S KKL + LGA +Y KE+F + KF +++ D +G +K V Sbjct: 203 VAATASTKKLDLLRTLGADLAIDYTKENFEDLPEKF------DVVYDAVG--ETDKAVKA 254 Query: 229 LALDGRWVLYGLMGGGDINGPLFSKLLFKRGSLITSLLRSRDNKYKQMLVNAFTEQILPH 288 + G+ V P +L +GS++ E++ P+ Sbjct: 255 VKEGGKVVTIVGPA----TPPAILFVLTSKGSVL--------------------EKLKPY 290 Query: 289 FSTEGPQRLLPVLDRI--YPVTEIQEAHKYMEANKNIGKIVL 328 + ++ PVLD YP T++ EA Y+E+++ GK+V+ Sbjct: 291 LES---GKVKPVLDPTSPYPFTKVVEAFGYLESSRATGKVVV 329 >4EJ6-A nrPDB Length = 370 Score = 181 bits (460), Expect = 3e-46, Method: Composition-based stats. Identities = 80/358 (22%), Positives = 135/358 (37%), Gaps = 50/358 (13%) Query: 1 MLAVHFDKPGGPENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNI 60 M AV + G N+ V+ V P PG ++L+KV A + D G++ P Sbjct: 24 MKAVRLESVG---NISVRNVGIPEPGPDDLLVKVEACGICGTDRHLLHGEFPSTP--PVT 78 Query: 61 LGLEASGHVAELGPGCQ------------------------GHWKIGD--TAMALLPGGG 94 LG E G V E G + G + A+ + GG Sbjct: 79 LGHEFCGIVVEAGSAVRDIAPGARITGDPNISCGRCPQCQAGRVNLCRNLRAIGIHRDGG 138 Query: 95 QAQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVG 154 A+YV VP IP L A E + L G ++AG V I G +G Sbjct: 139 FAEYVLVPRKQAFEIPLTLDPVHGA-FCEPLACCLHGVDLSG-IKAGSTVAILGG-GVIG 195 Query: 155 TAAIQLTRMAGAIPLVTAGSQK-KLQMAEKLGAAAGFNYKKEDFSEATLKFTK--GAGVN 211 +QL R+AGA ++ + Q K ++AE++GA A + D EA GV+ Sbjct: 196 LLTVQLARLAGATTVILSTRQATKRRLAEEVGATATVDPSAGDVVEAIAGPVGLVPGGVD 255 Query: 212 LILDCIG-GSYWEKNVNCLALDGRWVLYGLMGGGDINGPLFSKLLFKRGSLITSLLRSRD 270 ++++C G +++ G V+ G++ G+ +LF+ ++ S + Sbjct: 256 VVIECAGVAETVKQSTRLAKAGGTVVILGVLPQGEKVEIEPFDILFRELRVLGSFINPFV 315 Query: 271 NKYKQMLVNAFTEQILPHFSTEGPQRLLPVLDRIYPVTEIQEAHKYMEANKNIGKIVL 328 ++ LV G + ++ R + E + A + +V+ Sbjct: 316 HRRAADLV------------ATGAIEIDRMISRRISLDEAPDVISNPAAAGEVKVLVI 361 >2DQ4-A nrPDB Length = 343 Score = 179 bits (454), Expect = 2e-45, Method: Composition-based stats. Identities = 84/365 (23%), Positives = 143/365 (39%), Gaps = 59/365 (16%) Query: 1 MLAVHFDKPGGPENLYVKEVAKPSPGEGEVLLKVAASALNRADLM------QRQGQYDPP 54 M A K E L + + P PG GE+L++V A+++ DL +G+ P Sbjct: 1 MRA--LAKLAPEEGLTLVDRPVPEPGPGEILVRVEAASICGTDLHIWKWDAWARGRIRP- 57 Query: 55 PGASNILGLEASGHVAELGPGCQGHWKIGDTA---------------------------M 87 + G E SG V +GPG + ++GD + Sbjct: 58 ---PLVTGHEFSGVVEAVGPGVR-RPQVGDHVSLESHIVCHACPACRTGNYHVCLNTQIL 113 Query: 88 ALLPGGGQAQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIH 147 + GG A+YV VP P+ L + AAI E + A + G+ +G VLI Sbjct: 114 GVDRDGGFAEYVVVPAENAWVNPKDLPF-EVAAILEPFGNAVHTV-YAGSGVSGKSVLIT 171 Query: 148 AGLSGVGTAAIQLTRMAGAIPL-VTAGSQKKLQMAEKLGAAAGFNYKKEDFSEATLKFTK 206 G +G A + R +GA P+ V+ + +L A A N +ED E + T Sbjct: 172 -GAGPIGLMAAMVVRASGAGPILVSDPNPYRLAFARPY-ADRLVNPLEEDLLEVVRRVT- 228 Query: 207 GAGVNLILDCIGG-SYWEKNVNCLALDGRWVLYGLMGGGDINGPLFSKLLFKRGSLITSL 265 G+GV ++L+ G + + + L G + G+ I L +L+ + + + Sbjct: 229 GSGVEVLLEFSGNEAAIHQGLMALIPGGEARILGIPSD-PIRFDLAGELVMRGITAFG-I 286 Query: 266 LRSRDNKYKQMLVNAFTEQILPHFSTEGPQRLLPVLDRIYPVTEIQEAHKYMEANKNIGK 325 R + T G L P+L P++ +EA + + + + K Sbjct: 287 AGRRLWQ---------TWMQGTALVYSGRVDLSPLLTHRLPLSRYREAFGLLASGQAV-K 336 Query: 326 IVLEL 330 ++L+ Sbjct: 337 VILDP 341 >5LB9-A nrPDB Length = 385 Score = 174 bits (442), Expect = 4e-44, Method: Composition-based stats. Identities = 69/348 (19%), Positives = 124/348 (35%), Gaps = 40/348 (11%) Query: 2 LAVHFDKPGGPENLYVK---EVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGAS 58 AV + + G P+++ E+ + EV++K S +N +D+ Q QG Y P + Sbjct: 26 QAVLYTQHGEPKDVLFTQSFEIDDDNLAPNEVIVKTLGSPVNPSDINQIQGVYPSKPAKT 85 Query: 59 NILGL---------EASGHVAELGPGCQGHWKIGDTAMALLPG---------GGQAQYVT 100 G E V ++G + GD + G ++ Sbjct: 86 TGFGTTEPAAPCGNEGLFEVIKVGSNVSS-LEAGDWVIPSHVNFGTWRTHALGNDDDFIK 144 Query: 101 VP---EGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAG-DYVLIHAGLSGVGTA 156 +P + P GLT+ Q A I L A+ +L + G D+ + + G S VG Sbjct: 145 LPNPAQSKANGKPNGLTINQGATISVNPLVAYLMLTHYVKLTPGKDWFIQNGGTSAVGKY 204 Query: 157 AIQLTRMAGAIPLVTAGSQKKLQMA----EKLGAAAGFNYKKED---FSEATLKFTKGAG 209 A Q+ ++ + + L ++LGA + + F ++ K +G Sbjct: 205 ASQIGKLLNFNSISVIRDRPNLDEVVASLKELGATQVITEDQNNSREFGPTIKEWIKQSG 264 Query: 210 --VNLILDCIGGSYWEKNVNCLALDGRWVLYGLMGGGDINGPL---FSKLLFKRGSLITS 264 L L+C+GG L +G + YG M + P K G +T Sbjct: 265 GEAKLALNCVGGKSSTGIARKLNNNGLMLTYGGMSFQPVTIPTSLYIFKNFTSAGFWVTE 324 Query: 265 LLRSRDNKYKQMLVNAFTEQILPHFSTEGPQRLLPVLDRIYPVTEIQE 312 LL++ L + + + + D P+ E+ + Sbjct: 325 LLKNNKELKTSTLNQIIAWYEEGKLTD--AKSIETLYDGTKPLHELYQ 370 >6FG0-A nrPDB Length = 352 Score = 174 bits (441), Expect = 5e-44, Method: Composition-based stats. Identities = 75/363 (20%), Positives = 129/363 (35%), Gaps = 55/363 (15%) Query: 1 MLAVHFDKPGGPENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDP-PPGASN 59 M AV + + G V ++ P+PG GE+LLKV A+ L +D+ G Sbjct: 1 MKAVQYTEIG--SEPVVVDIPTPTPGPGEILLKVTAAGLCHSDITVMDMPAAQYAGGLPL 58 Query: 60 ILGLEASGHVAELGPGCQGHWKIGDTAMALLPGG-------------------------- 93 LG E G VAELG G G + +GD P G Sbjct: 59 TLGHEGVGTVAELGEGVTG-FGVGDAVAVYGPWGCGACHACARGRENYCTRAADLGITPP 117 Query: 94 ------GQAQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIH 147 A+Y+ V + L AA + +A LT + + V + + Sbjct: 118 GYGSPGSMAEYMIVDSARHLVPIGDLDPVAAAPLTDAGLTPYHAISRVLPLLGPGSTAVV 177 Query: 148 AGLSGVGTAAIQLTRMAG-AIPLVTAGSQKKLQMAEKLGAAAGFNYKKEDFSEATLKFTK 206 G+ G+G IQ+ R A + +L +A ++GA A ++A + T Sbjct: 178 IGVGGLGHVGIQILRAVSAARVIAVDLDDDRLALAREVGADAAVKSGAG-AADAIRELTG 236 Query: 207 GAGVNLILDCIGG-SYWEKNVNCLALDGRWVLYGLMGGGDINGPLFSKLLFKRGSLITSL 265 G G + D +G S + +A+DG + G+ G + + ++ S++T Sbjct: 237 GQGATAVFDFVGAQSTIDTAQQVVAVDGHISVVGIHAGA--HAKVGFWMIPFGASVVTPY 294 Query: 266 LRSRDNKYKQMLVNAFTEQILPHFSTEGPQRLLPVLDRIYPVTEIQEAHKYMEANKNIGK 325 +R + L + + + E A++ + G+ Sbjct: 295 WGTRSELME--------------VVALARAGRLDIHTETFTLDEGPAAYRRLREGSIRGR 340 Query: 326 IVL 328 V+ Sbjct: 341 GVV 343 >5VM2-A nrPDB Length = 347 Score = 171 bits (434), Expect = 3e-43, Method: Composition-based stats. Identities = 71/344 (20%), Positives = 125/344 (36%), Gaps = 53/344 (15%) Query: 12 PENLYVKEVAKPSPGEGEVLLKVAASALNRADLM-QRQGQYDPP--PGASNILGLEASGH 68 P + + P P E EVL+KV + +D+ G + PP P LG E +G Sbjct: 11 PGTMKIISAEIPVPKEDEVLIKVEYVGICGSDVHGFESGPFIPPKDPNQEIGLGHECAGT 70 Query: 69 VAELGPGCQGHWKIGDTA---------------------------MALLPG--GGQAQYV 99 V +G + +K GD MA P G Y+ Sbjct: 71 VVAVGSRVR-KFKPGDRVNIEPGVPCGHCRYCLEGKYNICPDVDFMATQPNYRGALTHYL 129 Query: 100 TVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQ 159 PE +P+ + + + A + + + +V+ G ++I G +G +Q Sbjct: 130 CHPESFTYKLPDNMDTMEGTLVEPAAVGMHAAM--LADVKPGKKIIIL-GAGCIGLMTLQ 186 Query: 160 LTRMAGAIPLVTAGS-QKKLQMAEKLGAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIG 218 + GA + +K+L MAE+LGA N KED +FT+ G +++ + G Sbjct: 187 ACKCLGATEIAVVDVLEKRLAMAEQLGATVVINGAKEDTIARCQQFTEDMGADIVFETAG 246 Query: 219 GSYWEKNVNCLA-LDGRWVLYGLMGGGDINGPLFSKLLFKRGSLITSLLRSRDNKYKQML 277 + K L G+ ++ G + G L + + N+Y Sbjct: 247 SAVTVKQAPYLVMRGGKIMIVGTVPGASAINF-----LKINREVTIQTVFRYANRY---- 297 Query: 278 VNAFTEQILPHFSTEGPQRLLPVLDRIYPVTEIQEAHKYMEANK 321 + + G + ++ IY ++Q+A + NK Sbjct: 298 ------PVTIEAISSGRFDVKSMVTHIYDYRDVQQAFEESVNNK 335 >4Y1B-A nrPDB Length = 425 Score = 169 bits (429), Expect = 1e-42, Method: Composition-based stats. Identities = 81/384 (21%), Positives = 133/384 (34%), Gaps = 81/384 (21%) Query: 4 VHFDKPGGPENLYVKEV-AKPSPGEGEVLLKVAASALNRADLMQRQGQY---------DP 53 + ++ G P + + EV P G G+VL+KV A+ +N ++ G+ Sbjct: 46 IRQERYGRPVDAFRTEVVDVPPVGPGQVLVKVMAAGVNYNNVWAALGEPLDVIAARQKQG 105 Query: 54 PPGASNILGLEASGHVAELGPGCQGHWKIG---------------DTAMALLP------- 91 +I G + SG V +G G K G D + P Sbjct: 106 ATEDFHIGGSDLSGIVWAVGDGV--RLKPGAEVVVLACRWDESAQDIRLGADPVTSSTQR 163 Query: 92 -------GGGQAQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLH--LVGNVQAGD 142 G AQ+ V E + P P+ L+ A+ TA++ L V+ GD Sbjct: 164 VWGYEENYGSFAQFAVVDEYMCHPKPQRLSWAAASCYMATAATAYRQLFGWEPHTVRPGD 223 Query: 143 YVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQMAEKLGAAAGFNYKKEDFSEATL 202 VLI G G+G+ AIQL R G IP+ S+++ + +LGA + ++ D Sbjct: 224 PVLIWGGAGGLGSIAIQLVRHVGGIPVAVVSSEERGEFCMRLGAKGWIDRREFDHWGRLP 283 Query: 203 KFTKGAGV------------------------NLILDCIGGSYWEKNVNCLALDGRWVLY 238 T + ++L+ G ++ G V+ Sbjct: 284 DTTDEEAMKQWLDGARAFGRRFWEVLGERRAPRIVLEHSGADTIPTSIYMADNAGMVVIC 343 Query: 239 GLMGGGDINGPLFSKLLFKRGSLITSLLRSRDNKYKQMLVNAFTEQILPHFSTEGPQRLL 298 G G NG + + L+ R K Q A + + Sbjct: 344 GGTTGY--NGDVDLRFLWMR------------QKRLQGSHAASAREAREITRLIDQGAID 389 Query: 299 PVLDRIYPVTEIQEAHKYMEANKN 322 P L R + EI AH+ + N++ Sbjct: 390 PCLSRTFGFEEIGLAHQLIHDNQH 413 >2J3K-A nrPDB Length = 345 Score = 167 bits (422), Expect = 8e-42, Method: Composition-based stats. Identities = 71/326 (21%), Positives = 135/326 (41%), Gaps = 26/326 (7%) Query: 18 KEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGA---SNILGLEASGH-VAELG 73 E+ P G VL+K + + R G+ DP A + G G+ V+ + Sbjct: 30 VELRVPE-GTNSVLVKNLYLS-CDPYMRIRMGKPDPSTAALAQAYTPGQPIQGYGVSRII 87 Query: 74 PGCQGHWKIGDTAMALLPGGGQAQY-VTVPEGLLMPIPEGLTLTQA---AAIPEAWLTAF 129 +K GD ++ +Y V P + + + + +TA+ Sbjct: 88 ESGHPDYKKGDLLWGIV---AWEEYSVITPMTHAHFKIQHTDVPLSYYTGLLGMPGMTAY 144 Query: 130 QLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQMAE-KLGAAA 188 + V + + G+ V + A VG QL +M G + +AGS++K+ + + K G Sbjct: 145 AGFYEVCSPKEGETVYVSAASGAVGQLVGQLAKMMGCYVVGSAGSKEKVDLLKTKFGFDD 204 Query: 189 GFNYKKEDFSEATLKFTKGAGVNLILDCIGGSYWEKNVNCLALDGRWVLYGLMGGGDING 248 FNYK+E A LK G+++ + +GG + + + + GR + G++ ++ Sbjct: 205 AFNYKEESDLTAALKRCFPNGIDIYFENVGGKMLDAVLVNMNMHGRIAVCGMISQYNLEN 264 Query: 249 PL----FSKLLFKRGSLITSLLRSRDNKYKQMLVNAFTEQILPHFSTEGPQRLLPVLDRI 304 S +++KR + ++ +KY + F E +LPH ++ V D Sbjct: 265 QEGVHNLSNIIYKRNRIQGFVVSDFYDKYSK-----FLEFVLPHIR---EGKITYVEDVA 316 Query: 305 YPVTEIQEAHKYMEANKNIGKIVLEL 330 + + EA + KN+GK V+ + Sbjct: 317 DGLEKAPEALVGLFHGKNVGKQVVVV 342 >3B70-A nrPDB Length = 371 Score = 157 bits (398), Expect = 4e-39, Method: Composition-based stats. Identities = 78/342 (22%), Positives = 128/342 (37%), Gaps = 41/342 (11%) Query: 21 AKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNILGLEASGHVAELGPGCQGHW 80 P +V ++V A A+N +D R GQ+ P LG + +G V +G H Sbjct: 30 PCPMLPRDQVYVRVEAVAINPSDTKMR-GQFATP---WAFLGTDYAGTVVAVGSDVT-HI 84 Query: 81 KIGDTAMALLP--------GGGQAQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLT---AF 129 ++GD G +QY + IP+GL+ QAAA+P T A Sbjct: 85 QVGDRVYGAQNEMCPRTPDQGAFSQYTVTRGRVWAKIPKGLSFEQAAALPAGISTAGLAM 144 Query: 130 QLLHLVGNVQAGD---------YVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQM 180 +LL L + D YVL++ G + T +Q+ R++G IP+ T S + Sbjct: 145 KLLGLPLPSPSADQPPTHSKPVYVLVYGGSTATATVTMQMLRLSGYIPIATC-SPHNFDL 203 Query: 181 AEKLGAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIGGSYWEKNVNCLALDGR-----W 235 A+ GA F+Y+ + ++ +TK + LDCI + E C A GR Sbjct: 204 AKSRGAEEVFDYRAPNLAQTIRTYTKNN-LRYALDCI--TNVESTTFCFAAIGRAGGHYV 260 Query: 236 VLYGLMG-----GGDINGPLFSKLLFKRGSLITSLLRSRDNKYKQMLVNAFTEQILPHFS 290 L +F GS + R ++ +I Sbjct: 261 SLNPFPEHAATRKMVTTDWTLGPTIFGEGSTWPAPYG-RPGSEEERQFGEDLWRIAGQLV 319 Query: 291 TEGPQRLLPVLDRIYPVTEIQEAHKYMEANKNIG-KIVLELP 331 +G P+ I++ + + + G K+V+ L Sbjct: 320 EDGRLVHHPLRVVQGGFDHIKQGMELVRKGELSGEKLVVRLE 361 >1HSO-A nrPDB Length = 374 Score = 156 bits (394), Expect = 1e-38, Method: Composition-based stats. Identities = 76/364 (20%), Positives = 124/364 (34%), Gaps = 67/364 (18%) Query: 13 ENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNILGLEASGHVAEL 72 + ++EV P EV +K+ A + D G P ILG EA+G V + Sbjct: 19 KPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTMVTP--LPVILGHEAAGIVESV 76 Query: 73 GPGCQGHWKIGDTAMA-LLPGGG------------------------------------- 94 G G K GD + +P G Sbjct: 77 GEGVTT-VKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDGTSRFTCRRK 135 Query: 95 ----------QAQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYV 144 +QY V E + I L + I + T + V V G Sbjct: 136 PIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTC 195 Query: 145 LIHAGLSGVGTAAIQLTRMAGA-IPLVTAGSQKKLQMAEKLGAAAGFNYK--KEDFSEAT 201 + GL GVG +AI + AGA + ++ K A++LGA N + K+ E Sbjct: 196 AVF-GLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVL 254 Query: 202 LKFTKGAGVNLILDCIGG--SYWEKNVNCLALDGRWVLYGLMGGGDINGPLFSKLLFKRG 259 + T G GV+ + IG + + C G V+ G+ N + LL Sbjct: 255 KEMTDG-GVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQ-NLSMNPMLLLTGR 312 Query: 260 SLITSLLRSRDNKYKQMLVNAFTEQILPHFSTEGPQRLLPVLDRIYPVTEIQEAHKYMEA 319 + ++L +K + + + + FS L ++ + P +I E + + Sbjct: 313 TWKGAILGGFKSK--ECVPKLVADFMAKKFS------LDALITHVLPFEKINEGFDLLHS 364 Query: 320 NKNI 323 K+I Sbjct: 365 GKSI 368 >1PL8-A nrPDB Length = 356 Score = 155 bits (393), Expect = 2e-38, Method: Composition-based stats. Identities = 66/344 (19%), Positives = 116/344 (33%), Gaps = 52/344 (15%) Query: 11 GPENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQ-GQYDP-PPGASNILGLEASGH 68 GP +L ++ P PG EVLL++ + + +D+ + G+ +LG EASG Sbjct: 15 GPGDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEASGT 74 Query: 69 VAELGPGCQGHWKIGDTA--------------------------MALLP--GGGQAQYVT 100 V ++G + H K GD P G ++ Sbjct: 75 VEKVGSSVK-HLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPPDDGNLCRFYK 133 Query: 101 VPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQL 160 +P+ +T + A + E G V G VL+ G +G + + Sbjct: 134 HNAAFCYKLPDNVTFEEGA-LIEPLSVGIHACRR-GGVTLGHKVLVC-GAGPIGMVTLLV 190 Query: 161 TRMAG-AIPLVTAGSQKKLQMAEKLGAAAGFNYKKEDFSEATLKFTKGAGVN--LILDCI 217 + G A +VT S +L A+++GA KE E K G + ++C Sbjct: 191 AKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLGCKPEVTIECT 250 Query: 218 GGSYWEKN-VNCLALDGRWVLYGLMGGGDINGPLFSKLLFKRGSLITSLLRSRDNKYKQM 276 G + + G VL GL L + + R+ K + Sbjct: 251 GAEASIQAGIYATRSGGTLVLVGLGSEMTTVPLLHAAI--------------REVDIKGV 296 Query: 277 LVNAFTEQILPHFSTEGPQRLLPVLDRIYPVTEIQEAHKYMEAN 320 T + + P++ +P+ + EA + + Sbjct: 297 FRYCNTWPVAISMLASKSVNVKPLVTHRFPLEKALEAFETFKKG 340 >4CPD-A nrPDB Length = 347 Score = 155 bits (393), Expect = 2e-38, Method: Composition-based stats. Identities = 76/368 (20%), Positives = 136/368 (36%), Gaps = 61/368 (16%) Query: 1 MLAVHFDKPGGPENLYVKEVAKPSPG-EGEVLLKVAASALNRADLMQRQGQYDPPPGASN 59 M AV F+ E + VKEV P + L++V + + +DL G+ PG + Sbjct: 1 MRAVVFENK---ERVAVKEVNAPRLQHPLDALVRVHLAGICGSDLHLYHGKIPVLPG--S 55 Query: 60 ILGLEASGHVAELGPGCQGHWKIGDTAMALLP---------------------------- 91 +LG E G V +G G Q + GD + Sbjct: 56 VLGHEFVGQVEAVGEGIQ-DLQPGDWVVGPFHIACGTCPYCRRHQYNLCERGGVYGYGPM 114 Query: 92 ----GGGQAQYVTVPEGLLM--PIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVL 145 G QA+ + VP + +P L+ +A + TA+ L G ++ GD V Sbjct: 115 FGNLQGAQAEILRVPFSNVNLRKLPPNLSPERAIFAGDILSTAYGGLIQ-GQLRPGDSVA 173 Query: 146 IHAGLSGVGTAAIQLTRMAGAIPL-VTAGSQKKLQMAEKLGAAAGFNYKKEDFSEATLKF 204 + G VG AI++ ++ GA + ++L+ A LGA N ++E+ Sbjct: 174 V-IGAGPVGLMAIEVAQVLGASKILAIDRIPERLERAASLGA-IPINAEQENPVRRVRSE 231 Query: 205 TKGAGVNLILDCIGGSYWEK-NVNCLALDGRWVLYGLMGGGDINGPLFSKLLFKRGSLIT 263 T G +L+L+ +GG+ + + GR G+ PL S L+ I Sbjct: 232 TNDEGPDLVLEAVGGAATLSLALEMVRPGGRVSAVGVDNAPSFPFPLASGLVKDLTFRIG 291 Query: 264 SL-LRSRDNKYKQMLVNAFTEQILPHFSTEGPQRLLPVLDRIYPVTEIQEAHKYMEANKN 322 + + +L G + ++ P+ E ++ + + Sbjct: 292 LANVHLYIDAVLALL-------------ASGRLQPERIVSHYLPLEEAPRGYELFDRKEA 338 Query: 323 IGKIVLEL 330 + K++L + Sbjct: 339 L-KVLLVV 345 >3FPC-A nrPDB Length = 352 Score = 155 bits (391), Expect = 3e-38, Method: Composition-based stats. Identities = 71/338 (21%), Positives = 117/338 (34%), Gaps = 47/338 (13%) Query: 17 VKEVAKPSPGEGEVLLKVAASALNRADLMQR-QGQYDPPPGASNILGLEASGHVAELGPG 75 E KP+PG + +++ A A +D+ +G ILG EA G V E+G Sbjct: 14 WIEKEKPAPGPFDAIVRPLAVAPCTSDIHTVFEGAIGERHNM--ILGHEAVGEVVEVGSE 71 Query: 76 CQGHWKIGDTAM--ALLPG----------------------------GGQAQY--VTVPE 103 + +K GD + A+ P G ++ V + Sbjct: 72 VK-DFKPGDRVVVPAITPDWRTSEVQRGYHQHSGGMLAGWKFSNVKDGVFGEFFHVNDAD 130 Query: 104 GLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRM 163 L +P+ + L A IP+ T F L N++ GD V + G+ VG ++ Sbjct: 131 MNLAHLPKEIPLEAAVMIPDMMTTGFHGAEL-ANIKLGDTVCV-IGIGPVGLMSVAGANH 188 Query: 164 AGAIPLVTAGSQKKL-QMAEKLGAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIGG-SY 221 GA + GS+K +A + GA NYK D E LK T G GV+ ++ G Sbjct: 189 LGAGRIFAVGSRKHCCDIALEYGATDIINYKNGDIVEQILKATDGKGVDKVVIAGGDVHT 248 Query: 222 WEKNVNCLALDGRWVLYGLMGGGDINGPLFSKLLFKRGSLITSLLRSRDNKYKQMLVNAF 281 + + V + +G GD R + + Sbjct: 249 FAQAVKMIKPGSDIGNVNYLGEGDNIDIP-------RSEWGVGMGHKHIHGGLCPGGRLR 301 Query: 282 TEQILPHFSTEGPQRLLPVLDRIYPVTEIQEAHKYMEA 319 E+++ + V I++A M+ Sbjct: 302 MERLIDLVFYKRVDPSKLVTHVFRGFDNIEKAFMLMKD 339 >3FSR-A nrPDB Length = 352 Score = 154 bits (390), Expect = 4e-38, Method: Composition-based stats. Identities = 72/338 (21%), Positives = 120/338 (35%), Gaps = 47/338 (13%) Query: 17 VKEVAKPSPGEGEVLLKVAASALNRADLMQR-QGQYDPPPGASNILGLEASGHVAELGPG 75 E KP+PG + +++ A A +D+ +G ILG EA G V E+G Sbjct: 14 WIEKEKPAPGPFDAIVRPLAVAPCTSDIHTVFEGAIGERHNM--ILGHEAVGEVVEVGSE 71 Query: 76 CQGHWKIGDTAM--ALLPG----------------------------GGQAQY--VTVPE 103 + +K GD + A+ P G ++ V + Sbjct: 72 VK-DFKPGDRVVVPAITPDWRTSEVQRGYHQHSGGMLAGWKFSNVKDGVFGEFFHVNDAD 130 Query: 104 GLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRM 163 L +P+ + L A IP+ T F L ++Q G V++ G+ VG I ++ Sbjct: 131 MNLAHLPKEIPLEAAVMIPDMMTTGFHGAEL-ADIQMGSSVVV-IGIGAVGLMGIAGAKL 188 Query: 164 AGAIPLVTAGSQKKL-QMAEKLGAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIGGS-Y 221 GA ++ GS+ + A+ GA NYK + +K T G GV+ ++ GGS Sbjct: 189 RGAGRIIGVGSRPICVEAAKFYGATDILNYKNGHIVDQVMKLTNGKGVDRVIMAGGGSET 248 Query: 222 WEKNVNCLALDGRWVLYGLMGGGDINGPLFSKLLFKRGSLITSLLRSRDNKYKQMLVNAF 281 + V+ + G G GD LL R + Sbjct: 249 LSQAVSMVKPGGIISNINYHGSGD-------ALLIPRVEWGCGMAHKTIKGGLCPGGRLR 301 Query: 282 TEQILPHFSTEGPQRLLPVLDRIYPVTEIQEAHKYMEA 319 E+++ + V I++A M+ Sbjct: 302 MERLIDLVFYKRVDPSKLVTHVFRGFDNIEKAFMLMKD 339 >1U3W-A nrPDB Length = 374 Score = 153 bits (387), Expect = 9e-38, Method: Composition-based stats. Identities = 77/371 (20%), Positives = 128/371 (34%), Gaps = 68/371 (18%) Query: 13 ENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNILGLEASGHVAEL 72 + ++EV P EV +K+ A+ + R+D G P ILG EA+G V + Sbjct: 19 KPFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNLVTP--LPVILGHEAAGIVESV 76 Query: 73 GPGCQGHWKIGDTAMALL-PGGG------------------------------------- 94 G G K GD + L P G Sbjct: 77 GEGVTT-VKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDGTRRFTCSGK 135 Query: 95 ----------QAQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYV 144 +QY V E + I L + I + T + V V G Sbjct: 136 PIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTPGSTC 195 Query: 145 LIHAGLSGVGTAAIQLTRMAGA-IPLVTAGSQKKLQMAEKLGAAAGFNYK--KEDFSEAT 201 + GL GVG + + + AGA + ++ K A++LGA N + K+ E Sbjct: 196 AVF-GLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVL 254 Query: 202 LKFTKGAGVNLILDCIG--GSYWEKNVNCLALDGRWVLYGLMGGGDINGPLFSKLLFKRG 259 + T G GV+ + IG + + C G V+ G+ N + LL Sbjct: 255 KEMTDG-GVDFSFEVIGQLDTMMASLLCCHEACGTSVIVGVPPDSQ-NLSINPMLLLTGR 312 Query: 260 SLITSLLRSRDNKYKQMLVNAFTEQILPHFSTEGPQRLLPVLDRIYPVTEIQEAHKYMEA 319 + ++ +K + + + + FS L ++ + P +I E + + Sbjct: 313 TWKGAIFGGFKSK--ESVPKLVADFMAKKFS------LDALITNVLPFEKINEGFDLLRS 364 Query: 320 NKNIGKIVLEL 330 K+I + VL Sbjct: 365 GKSI-RTVLTF 374 >1V3V-A nrPDB Length = 333 Score = 153 bits (386), Expect = 1e-37, Method: Composition-based stats. Identities = 68/327 (20%), Positives = 123/327 (37%), Gaps = 28/327 (8%) Query: 13 ENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNILGLEASGHVAEL 72 + +K V P GEVLL+ ++ D R GA ++G + + V Sbjct: 24 SDFELKTVELPPLKNGEVLLEALFLSV---DPYMRIASKRLKEGA-VMMGQQVARVVESK 79 Query: 73 GPGCQGHWKIGDTAMALLPGGGQAQYVTVP----EGLLMPIPEGLTLTQA-AAIPEAWLT 127 + G +A G + E LL P+ L L+ A I LT Sbjct: 80 ----NSAFPAGSIVLA---QSGWTTHFISDGKGLEKLLTEWPDKLPLSLALGTIGMPGLT 132 Query: 128 AFQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQMAEKLGAA 187 A+ L V V+ G+ VL+ A VG+ Q+ ++ G + AGS +K+ +++G Sbjct: 133 AYFGLLEVCGVKGGETVLVSAAAGAVGSVVGQIAKLKGCKVVGAAGSDEKIAYLKQIGFD 192 Query: 188 AGFNYKKEDFSEATLKFTKGAGVNLILDCIGGSYWEKNVNCLALDGRWVLYGLMG----- 242 A FNYK + E LK G + D +GG + ++ + G+ + G + Sbjct: 193 AAFNYKTVNSLEEALKKASPDGYDCYFDNVGGEFLNTVLSQMKDFGKIAICGAISVYNRM 252 Query: 243 GGDINGPLFSKLLFKRGSLITSLLRSRDNKYKQMLVNAFTEQILPHFSTEGPQRLLPVLD 302 GP +++K+ + ++ ++ + + +L ++ Sbjct: 253 DQLPPGPSPESIIYKQLRIEGFIVYRWQGDVREKALRDLMKWVLE-------GKIQYHEH 305 Query: 303 RIYPVTEIQEAHKYMEANKNIGKIVLE 329 + A M N+GK V+ Sbjct: 306 VTKGFENMPAAFIEMLNGANLGKAVVT 332 >3IP1-A nrPDB Length = 404 Score = 152 bits (384), Expect = 2e-37, Method: Composition-based stats. Identities = 78/367 (21%), Positives = 138/367 (37%), Gaps = 63/367 (17%) Query: 11 GPENLYVKEVAKPSP-GEGEVLLKVAASALNRADLMQRQGQ------YDPPPGASNILGL 63 + V+EV +P E+++KV A + +D+ Q Y G LG Sbjct: 38 RYPEVRVEEVPEPRIEKPTEIIIKVKACGICGSDVHMAQTDEEGYILYPGLTGFPVTLGH 97 Query: 64 EASGHVAELGPGC----------------------QGHWKIGDTA----------MALLP 91 E SG V E GP GH + + Sbjct: 98 EFSGVVVEAGPEAINRRTNKRFEIGEPVCAEEMLWCGHCRPCAEGFPNHCENLNELGFNV 157 Query: 92 GGGQAQYVTVPEGLLMPIPE------GLTLTQAAAIPEAWLTAFQLL-HLVGNVQAGDYV 144 G A+YV V + E G L A ++ E A+ + G ++ GD V Sbjct: 158 DGAFAEYVKVDAKYAWSLRELEGVYEGDRLFLAGSLVEPTSVAYNAVIVRGGGIRPGDNV 217 Query: 145 LIHAGLSGVGTAAIQLTRMAGA-IPLVTAGSQKKLQMAEKLGAAAGFNYKKEDFSEATLK 203 +I G +G AA+ + + AGA +++ S+ + +A++LGA + KE+F EA L Sbjct: 218 VILGG-GPIGLAAVAILKHAGASKVILSEPSEVRRNLAKELGADHVIDPTKENFVEAVLD 276 Query: 204 FTKGAGVNLILDCIGGS--YWEKNVNCL-ALDGRWVLYGLMGGGDINGPLFSKLL-FKRG 259 +T G G L L+ G W + + G ++ D PL ++ +R Sbjct: 277 YTNGLGAKLFLEATGVPQLVWPQIEEVIWRARGINATVAIVARADAKIPLTGEVFQVRRA 336 Query: 260 SLITSLLRSRDNKYKQMLVNAFTEQILPHFSTEGPQRLLPVLDRIYPVTEIQEAHKYMEA 319 ++ S S + +++ G + ++ + + EI E K ++ Sbjct: 337 QIVGSQGHSGHGTFPRVI----------SLMASGMD-MTKIISKTVSMEEIPEYIKRLQT 385 Query: 320 NKNIGKI 326 +K++ K+ Sbjct: 386 DKSLVKV 392 >1MC5-A nrPDB Length = 374 Score = 152 bits (383), Expect = 2e-37, Method: Composition-based stats. Identities = 75/379 (19%), Positives = 127/379 (33%), Gaps = 68/379 (17%) Query: 2 LAVHFDKPGGPENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNIL 61 A + G P L ++E+ P EV +K+ A+A+ D G DP IL Sbjct: 9 KAAVAWEAGKP--LSIEEIEVAPPKAHEVRIKIIATAVCHTDAYTLSGA-DPEGCFPVIL 65 Query: 62 GLEASGHVAELGPGCQGHWKIGDTAMA-LLPGGGQAQYVTVPEGLLMPI----------P 110 G E +G V +G G K GDT + +P G+ ++ P+ L P Sbjct: 66 GHEGAGIVESVGEGVT-KLKAGDTVIPLYIPQCGECKFCLNPKTNLCQKIRVTQGKGLMP 124 Query: 111 EGL-------------------------------------TLTQAAAIPEAWLTAFQLLH 133 +G L + + T + Sbjct: 125 DGTSRFTCKGKTILHYMGTSTFSEYTVVADISVAKIDPLAPLDKVCLLGCGISTGYGAAV 184 Query: 134 LVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGA-IPLVTAGSQKKLQMAEKLGAAAGFNY 192 ++ G V GL GVG A I ++AGA + ++ K A++ GA N Sbjct: 185 NTAKLEPG-SVCAVFGLGGVGLAVIMGCKVAGASRIIGVDINKDKFARAKEFGATECINP 243 Query: 193 K--KEDFSEATLKFTKGAGVNLILDCIGGSYWEKNVNCLALDGRWVLYGLMGGGDINGPL 250 + + E ++ T G GV+ +CIG V + G + Sbjct: 244 QDFSKPIQEVLIEMTDG-GVDYSFECIGN------VKVMRAALEACHKGWGVSVVVGVAA 296 Query: 251 FSKLLFKRGSLITSLLRSRDNKYKQMLVNAFTEQILPHFSTEGPQRLLPVLDRIYPVT-- 308 + + R L+ R K E + S +++ + ++ Sbjct: 297 SGEEIATRPF---QLVTGRTWKGTAFGGWKSVESVPKLVSEYMSKKIKVDEFVTHNLSFD 353 Query: 309 EIQEAHKYMEANKNIGKIV 327 EI +A + M + K+I +V Sbjct: 354 EINKAFELMHSGKSIRTVV 372 >1HSZ-A nrPDB Length = 374 Score = 151 bits (382), Expect = 3e-37, Method: Composition-based stats. Identities = 79/382 (20%), Positives = 129/382 (33%), Gaps = 70/382 (18%) Query: 2 LAVHFDKPGGPENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNIL 61 A + P +++V P EV +K+ A + R D G P IL Sbjct: 10 KAAVLWEVKKP--FSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVSGNLVTP--LPVIL 65 Query: 62 GLEASGHVAELGPGCQGHWKIGDTAMALL-PGGG-------------------------- 94 G EA+G V +G G K GD + L P G Sbjct: 66 GHEAAGIVESVGEGVTT-VKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQ 124 Query: 95 ---------------------QAQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLH 133 +QY V E + I L + I + T + Sbjct: 125 DGTRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAV 184 Query: 134 LVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGA-IPLVTAGSQKKLQMAEKLGAAAGFNY 192 V V G + GL GVG +A+ + AGA + ++ K A++LGA N Sbjct: 185 NVAKVTPGSTCAVF-GLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINP 243 Query: 193 K--KEDFSEATLKFTKGAGVNLILDCIGG--SYWEKNVNCLALDGRWVLYGLMGGGDING 248 + K+ E + T G GV+ + IG + + C G V+ G+ N Sbjct: 244 QDYKKPIQEVLKEMTDG-GVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQ-NL 301 Query: 249 PLFSKLLFKRGSLITSLLRSRDNKYKQMLVNAFTEQILPHFSTEGPQRLLPVLDRIYPVT 308 + LL + ++ +K + + + + FS L ++ + P Sbjct: 302 SINPMLLLTGRTWKGAVYGGFKSK--EGIPKLVADFMAKKFS------LDALITHVLPFE 353 Query: 309 EIQEAHKYMEANKNIGKIVLEL 330 +I E + + K+I + VL Sbjct: 354 KINEGFDLLHSGKSI-RTVLTF 374 >3COS-A nrPDB Length = 381 Score = 150 bits (380), Expect = 5e-37, Method: Composition-based stats. Identities = 77/378 (20%), Positives = 129/378 (34%), Gaps = 70/378 (18%) Query: 2 LAVHFDKPGGPENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNIL 61 A + G P L ++EV P EV +++ A++L D +++ I+ Sbjct: 12 KAAIAWEAGKP--LCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEGL-AFPVIV 68 Query: 62 GLEASGHVAELGPGCQGHWKIGDTAMALLPG----------------------------- 92 G EA+G V +GPG + K GD + L Sbjct: 69 GHEAAGIVESIGPGVT-NVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLKSPASDQ 127 Query: 93 -----------------------GGQAQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAF 129 +QY V + L I + L + + + T + Sbjct: 128 QLMEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGCGFSTGY 187 Query: 130 QLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGA-IPLVTAGSQKKLQMAEKLGAAA 188 V G + GL GVG +A+ + AGA + + +K A+ LGA Sbjct: 188 GAAINNAKVTPGSTCAVF-GLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKALGATD 246 Query: 189 GFNYKK--EDFSEATLKFTKGAGVNLILDCIGGSYWEK-NVNCLALDGRWVLYGLMGGGD 245 N + + E ++ TKG GV+ LDC GGS K ++C + + G Sbjct: 247 CLNPRDLHKPIQEVIIELTKG-GVDFALDCAGGSETMKAALDCTTAGWGSCTFIGVAAGS 305 Query: 246 INGPLFSKLLFKRGSLITSLLRSRDNKYKQMLVNAFTEQILPHFSTEGPQRLLPVLDRIY 305 +F + L ++ + K + T+ F+ L ++ Sbjct: 306 KGLTVFPEELIIGRTINGTFFG--GWKSVDSIPKLVTDYKNKKFN------LDALVTHTL 357 Query: 306 PVTEIQEAHKYMEANKNI 323 P +I EA M K+I Sbjct: 358 PFDKISEAFDLMNQGKSI 375 >5KIA-A nrPDB Length = 351 Score = 150 bits (379), Expect = 7e-37, Method: Composition-based stats. Identities = 66/360 (18%), Positives = 132/360 (36%), Gaps = 52/360 (14%) Query: 1 MLAVHFDKPGGPENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQ-GQYDPPP-GAS 58 M A+ + G L + V KP G +VL+K+ +A+ D+ + + Sbjct: 9 MKALAKLERGP--GLTLTRVKKPEVGHNDVLIKIRRTAICGTDIHIWKWDDWAQKTIPVP 66 Query: 59 NILGLEASGHVAELGPGCQGHWKIGDTA---------------------------MALLP 91 +G E G + E+G +G + IGD + + Sbjct: 67 MHVGHEYVGEIVEMGQEVRG-FSIGDRVSGEGHITCGFCRNCRAGRRHLCRNTVGVGVNR 125 Query: 92 GGGQAQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLS 151 G A+Y+ +P IP ++ AA L G+ VLI G Sbjct: 126 EGAFAEYLAIPAFNAFKIPPEISDDLAAIFDPFGNATHTALSFNLV---GEDVLIT-GAG 181 Query: 152 GVGTAAIQLTRMAGAI-PLVTAGSQKKLQMAEKLGAAAGFNYKKEDFSEATLKFTKGAGV 210 +G A+ + + GA ++T + +L +A ++GA N +E + G Sbjct: 182 PIGVMAVAIAKHVGARNVVITDINDYRLDLARRMGATRAVNVSRESLRDVMADLHMTEGF 241 Query: 211 NLILDCIG-GSYWEKNVNCLALDGRWVLYGLMGGGDINGPLFSKLLFKRGSLITSLLRSR 269 ++ L+ G S + + + G+ L G+ +++++FK + R Sbjct: 242 DVGLEMSGVPSAFTSLLESMNHGGKVALLGIPPAQ--TAIDWNQVIFKGLEIKGIYG--R 297 Query: 270 DNKYKQMLVNAFTEQILPHFSTEGPQRLLPVLDRIYPVTEIQEAHKYMEANKNIGKIVLE 329 + + A + L L P++ + V + ++ M + ++ GK++L+ Sbjct: 298 EMFETWYKMVAMLQSGLD---------LSPIITHRFAVDDYEKGFAAMLSGES-GKVILD 347 >1KEV-A nrPDB Length = 351 Score = 150 bits (379), Expect = 8e-37, Method: Composition-based stats. Identities = 61/270 (22%), Positives = 102/270 (37%), Gaps = 40/270 (14%) Query: 11 GPENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQR-QGQYDPPPGASNILGLEASGHV 69 G L E +P G + +++ A + +D+ +G + ILG EA G V Sbjct: 8 GINKLGWIEKERPVAGSYDAIVRPLAVSPCTSDIHTVFEGALGD--RKNMILGHEAVGEV 65 Query: 70 AELGPGCQGHWKIGDTAM------------------------------ALLPGGGQAQY- 98 E+G + +K GD + + G +Y Sbjct: 66 VEVGSEVK-DFKPGDRVIVPCTTPDWRSLEVQAGFQQHSNGMLAGWKFSNFKDGVFGEYF 124 Query: 99 -VTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAA 157 V + L +P+ + L A I + T F L ++Q G V++ G+ VG Sbjct: 125 HVNDADMNLAILPKDMPLENAVMITDMMTTGFHGAEL-ADIQMGSSVVV-IGIGAVGLMG 182 Query: 158 IQLTRMAGAIPLVTAGSQKKL-QMAEKLGAAAGFNYKKEDFSEATLKFTKGAGVNLILDC 216 I ++ GA ++ GS+ + A+ GA NYK + +K T G GV+ ++ Sbjct: 183 IAGAKLRGAGRIIGVGSRPICVEAAKFYGATDILNYKNGHIVDQVMKLTNGKGVDRVIMA 242 Query: 217 IGGS-YWEKNVNCLALDGRWVLYGLMGGGD 245 GGS + V+ + G G GD Sbjct: 243 GGGSETLSQAVSMVKPGGIISNINYHGSGD 272 >5TNX-A nrPDB Length = 383 Score = 148 bits (374), Expect = 3e-36, Method: Composition-based stats. Identities = 74/372 (19%), Positives = 121/372 (32%), Gaps = 68/372 (18%) Query: 13 ENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNILGLEASGHVAEL 72 ++ +P EVL++V A+ L DL+ R Y P +LG E +G V + Sbjct: 28 APFSIEPARIRAPRGDEVLVRVVATGLCHTDLIVRDQYYPVP--LPAVLGHEGAGVVEAV 85 Query: 73 GPGCQ-----------------------GHWKIGDTAMALLPGGG--------------- 94 GP + GH AL GG Sbjct: 86 GPNVKTLAAGDHVVLTYGACGHCASCAGGHGAYCRQFFALNFGGADADGQTALRDAAGEP 145 Query: 95 ----------QAQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYV 144 A Y E + +P+ L + T + V+ G Sbjct: 146 LHDHFFAQSSFASYALARENNAIKVPKEAPLELLGPLGCGIQTGAGAVINSLAVRTGSSF 205 Query: 145 LIHAGLSGVGTAAIQLTRMAGAI-PLVTAGSQKKLQMAEKLGAAAGFNYKKEDFSEATLK 203 G VG +A+ R+AGA + +L +A +LGA N K+ D +A + Sbjct: 206 A-SFGAGAVGMSAVMAARIAGATTIIAVDIVPSRLALALELGATHAINSKEVDVVDAIRE 264 Query: 204 FTKGAGVNLILDCIG-GSYWEKNVNCLALDGRWVLYGLMGGGDINGPLFSKLLFKRGSLI 262 T G GV+ L+ G + + ++ L G + G G + LL ++ Sbjct: 265 ITGG-GVDYALESTGLPAVLSQGIDALGSRGTMGVVGAPKLGTKAEFDVNSLLLGGHTIR 323 Query: 263 TSLLRSRDNKYKQMLVNAFTEQILPHFSTEGPQRLLPV--LDRIYPVTEIQEAHKYMEAN 320 + + +P Q P L + YP+ +I +A + Sbjct: 324 GIVEGDS-----------VPQTFIPQLVQLHLQGRFPFDRLVKFYPLEQINQAAADSSSG 372 Query: 321 KNIGKIVLELPQ 332 + K +L LP Sbjct: 373 ITL-KPILRLPH 383 >4OH1-A nrPDB Length = 351 Score = 147 bits (372), Expect = 5e-36, Method: Composition-based stats. Identities = 66/346 (19%), Positives = 122/346 (35%), Gaps = 51/346 (14%) Query: 19 EVAKPSPGEGEVLLKVAASALNRADLMQRQGQYD-----PPPGASNILGLEASGHVAELG 73 E P P + E+ +KV +++ +D G G E SG + ++G Sbjct: 25 EAPMPEPKDEEIRIKVVYASICGSDTHILTGNLGEMESTTRSMLPMSFGHELSGVIDKVG 84 Query: 74 PGC-QGHWKIGDTAMALLPG-----------------------GGQAQYVTVPEGLLMPI 109 + +K+G +A G ++Y + PI Sbjct: 85 STAEKMGFKVGQKVVANYAKYCGCCENCREGKVNLCSNMGYRMNGFSEYAVYHMSQIFPI 144 Query: 110 PEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPL 169 P+ L A LT + G V I G G+G +QL R+AGA + Sbjct: 145 PDDADLKDYA--LVEPLTVALSSAEQAKISYGKSVAIM-GAGGLGMMLVQLARLAGASTI 201 Query: 170 VT-AGSQKKLQMAEKLGAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIGGSYWEK-NVN 227 +KL++A + GA N +E +E ++ G + +L+ G + K + Sbjct: 202 TVFDIVPEKLELALENGADYALNSAEEGVAERAIELAGGR-YDCVLEGTGATAAAKLGLQ 260 Query: 228 CLALDGRWVLYGLMGGGDI-NGPLFSKLLFKRGSLITSLLRSRDNKYKQMLVNAFTEQIL 286 LA DG V + + G I L S L + + + + Q Sbjct: 261 LLARDGDAVYFAMYGKDPILPVNLQSDLYWDQKHIHGMIQG--------------AWQFP 306 Query: 287 PHFSTEGPQRLLPVLDRIYPVTEIQEAHKYMEANKNIGKIVLELPQ 332 ++ + + +T ++A + + + K KIV+++ + Sbjct: 307 KSIRMIPRMDFSKIIQKEHTLTNYKQAFEDLYSKK-YAKIVIKMDE 351 >3QE3-A nrPDB Length = 355 Score = 147 bits (371), Expect = 6e-36, Method: Composition-based stats. Identities = 65/344 (18%), Positives = 115/344 (33%), Gaps = 52/344 (15%) Query: 11 GPENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQ-GQY-DPPPGASNILGLEASGH 68 GP +L ++ P PG EVLLK+ + + +D+ Q G+ D +LG EASG Sbjct: 14 GPGDLRLENYPIPEPGPNEVLLKMHSVGICGSDVHYWQHGRIGDFVVKKPMVLGHEASGT 73 Query: 69 VAELGPGCQGHWKIGDTA--------------------------MALLP--GGGQAQYVT 100 V ++G + H + GD P G ++ Sbjct: 74 VVKVGSLVR-HLQPGDRVAIQPGAPRQTDEFCKIGRYNLSPTIFFCATPPDDGNLCRFYK 132 Query: 101 VPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQL 160 +P+ +T + A + E G V G+ VL+ G +G + Sbjct: 133 HNANFCYKLPDNVTFEEGA-LIEPLSVGIHACRRAG-VTLGNKVLVC-GAGPIGLVNLLA 189 Query: 161 TRMAG-AIPLVTAGSQKKLQMAEKLGAAAGFNYKKEDFSEATLKFTK--GAGVNLILDCI 217 + G A +VT S +L A+++GA E E K G+ + ++C Sbjct: 190 AKAMGAAQVVVTDLSASRLSKAKEVGADFILEISNESPEEIAKKVEGLLGSKPEVTIECT 249 Query: 218 GGSYWEKN-VNCLALDGRWVLYGLMGGGDINGPLFSKLLFKRGSLITSLLRSRDNKYKQM 276 G + + G VL GL G ++ + + Sbjct: 250 GVETSIQAGIYATHSGGTLVLVGL--GSEMTSVPLVHAATREVDIKGVFRYCN------- 300 Query: 277 LVNAFTEQILPHFSTEGPQRLLPVLDRIYPVTEIQEAHKYMEAN 320 T + + P++ +P+ + EA + + Sbjct: 301 -----TWPMAISMLASKSVNVKPLVTHRFPLEKALEAFETSKKG 339 >2Y05-A nrPDB Length = 328 Score = 144 bits (364), Expect = 4e-35, Method: Composition-based stats. Identities = 67/322 (20%), Positives = 117/322 (36%), Gaps = 18/322 (5%) Query: 13 ENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNILGLEASGHV--- 69 + +K P GEVLL+ + D R G ++G + + V Sbjct: 19 SDFELKTSELPPLKNGEVLLEALFLTV---DPYMRVAAKRLKEG-DTMMGQQVAKVVESK 74 Query: 70 -AELGPGCQGHWKIGDTAMALLPGGGQAQYVTVPEGLLMPIPEGLTLTQA-AAIPEAWLT 127 L G G + G + LL P+ + L+ A + LT Sbjct: 75 NVALPKGTIVLASPG-WTTHSISDGKDLE------KLLTEWPDTIPLSLALGTVGMPGLT 127 Query: 128 AFQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQMAEKLGAA 187 A+ L + V+ G+ V+++A VG+ Q+ ++ G + GS +K+ +KLG Sbjct: 128 AYFGLLEICGVKGGETVMVNAAAGAVGSVVGQIAKLKGCKVVGAVGSDEKVAYLQKLGFD 187 Query: 188 AGFNYKKEDFSEATLKFTKGAGVNLILDCIGGSYWEKNVNCLALDGRWVLYGLMGGGDIN 247 FNYK + E TLK G + D +GG + + + GR + G + + Sbjct: 188 VVFNYKTVESLEETLKKASPDGYDCYFDNVGGEFSNTVIGQMKKFGRIAICGAISTYNRT 247 Query: 248 GPLFSKLLFKRGSLITSLLRSRDNKYKQMLVNAFTEQILPHFSTEGPQRLLPVLDRIYPV 307 GPL + + + Q + L + EG ++ I Sbjct: 248 GPLPPGPPPEIVIYQELRMEAFVVYRWQGDARQKALKDLLKWVLEG--KIQYKEYIIEGF 305 Query: 308 TEIQEAHKYMEANKNIGKIVLE 329 + A M N+GK +++ Sbjct: 306 ENMPAAFMGMLKGDNLGKTIVK 327 >1F8F-A nrPDB Length = 371 Score = 144 bits (364), Expect = 4e-35, Method: Composition-based stats. Identities = 66/369 (17%), Positives = 119/369 (32%), Gaps = 67/369 (18%) Query: 4 VHFDKPGGPENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNILGL 63 + P + ++ + P EVL+KV A+ + DL+ R +Y P +LG Sbjct: 8 IAAVTPCKGADFELQALKIRQPQGDEVLVKVVATGMCHTDLIVRDQKYPVP--LPAVLGH 65 Query: 64 EASGHVAELGPGCQGHWKIGDTAM------------------------------------ 87 E SG + +GP ++GD + Sbjct: 66 EGSGIIEAIGPNVTE-LQVGDHVVLSYGYCGKCTQCNTGNPAYCSEFFGRNFSGADSEGN 124 Query: 88 -------------ALLPGGGQAQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHL 134 A Y E + + + + + + T Sbjct: 125 HALCTHDQGVVNDHFFAQSSFATYALSRENNTVKVTKDVPIELLGPLGCGIQTGAGACIN 184 Query: 135 VGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPL-VTAGSQKKLQMAEKLGAAAGFNYK 193 V + G VG +A+ ++ GA + + +L++A++LGA N K Sbjct: 185 ALKVTPASSFVTW-GAGAVGLSALLAAKVCGASIIIAVDIVESRLELAKQLGATHVINSK 243 Query: 194 KEDFSEATLKFTKGAGVNLILDCIGGSY-WEKNVNCLALDGRWVLYGLMGGGDINGPLFS 252 +D A + T G GVN L+ G ++ V+ L + G+ + G G + Sbjct: 244 TQDPVAAIKEITDG-GVNFALESTGSPEILKQGVDALGILGKIAVVGAPQLGTTAQFDVN 302 Query: 253 KLLFKRGSLITSLLRS-RDNKYKQMLVNAFTEQILPHFSTEGPQRLLPVLDRIYPVTEIQ 311 LL +++ + S K+ LV + + P L + Y EI Sbjct: 303 DLLLGGKTILGVVEGSGSPKKFIPELVRLYQQGKFPFDQ----------LVKFYAFDEIN 352 Query: 312 EAHKYMEAN 320 +A Sbjct: 353 QAAIDSRKG 361 >1YKF-A nrPDB Length = 352 Score = 144 bits (363), Expect = 5e-35, Method: Composition-based stats. Identities = 59/265 (22%), Positives = 99/265 (37%), Gaps = 40/265 (15%) Query: 17 VKEVAKPSPGEGEVLLKVAASALNRADLMQR-QGQYDPPPGASNILGLEASGHVAELGPG 75 E KP+PG + +++ A A +D+ +G ILG EA G V E+G Sbjct: 14 WIEKEKPAPGPFDAIVRPLAVAPCTSDIHTVFEGAIGERHNM--ILGHEAVGEVVEVGSE 71 Query: 76 CQGHWKIGDTAM--ALLPG----------------------------GGQAQY--VTVPE 103 + +K GD + A+ P G ++ V + Sbjct: 72 VK-DFKPGDRVVVPAITPDWRTSEVQRGYHQHSGGMLAGWKFSNVKDGVFGEFFHVNDAD 130 Query: 104 GLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRM 163 L +P+ + L A IP+ T F L +++ G V + G+ VG A+ ++ Sbjct: 131 MNLAHLPKEIPLEAAVMIPDMMTTGFHGAEL-ADIELGATVAVL-GIGPVGLMAVAGAKL 188 Query: 164 AGAIPLVTAGSQKKL-QMAEKLGAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIGGSYW 222 GA ++ GS+ A+ GA NYK + T+G GV+ + G + Sbjct: 189 RGAGRIIAVGSRPVCVDAAKYYGATDIVNYKDGPIESQIMNLTEGKGVDAAIIAGGNADI 248 Query: 223 -EKNVNCLALDGRWVLYGLMGGGDI 246 V + G G G++ Sbjct: 249 MATAVKIVKPGGTIANVNYFGEGEV 273 >4RQU-A nrPDB Length = 375 Score = 141 bits (356), Expect = 4e-34, Method: Composition-based stats. Identities = 76/376 (20%), Positives = 124/376 (32%), Gaps = 69/376 (18%) Query: 2 LAVHFDKPGGPENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNIL 61 A + G P L ++EV P + EV +K+ ++L D+ + + P I Sbjct: 7 KAAVAWEAGKP--LVIEEVEVAPPQKHEVRIKILFTSLCHTDVYFWEAK-GQTPLFPRIF 63 Query: 62 GLEASGHVAELGPGCQGHWKIGDTAMALLPG-------------------------GG-- 94 G EA G V +G G + GD + + G GG Sbjct: 64 GHEAGGIVESVGEGVT-DLQPGDHVLPIFTGECGECRHCHSEESNMCDLLRINTERGGMI 122 Query: 95 ----------------------QAQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLL 132 ++Y V G + I L + + T Sbjct: 123 HDGESRFSINGKPIYHFLGTSTFSEYTVVHSGQVAKINPDAPLDKVCIVSCGLSTGLGAT 182 Query: 133 HLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGA-IPLVTAGSQKKLQMAEKLGAAAGFN 191 V + G V I GL VG A + R+AGA + + K+ A++ G N Sbjct: 183 LNVAKPKKGQSVAIF-GLGAVGLGAAEGARIAGASRIIGVDFNSKRFDQAKEFGVTECVN 241 Query: 192 YKKED--FSEATLKFTKGAGVNLILDCIGG-SYWEKNVNCLALD-GRWVLYGLMGGGDIN 247 K D + + T G GV+ ++C G + C+ G VL G+ D Sbjct: 242 PKDHDKPIQQVIAEMTDG-GVDRSVECTGSVQAMIQAFECVHDGWGVAVLVGVPSKDDAF 300 Query: 248 GPLFSKLLFKRGSLITSLLRSRDNKYKQMLVNAFTEQILPHFSTEGPQRLLPVLDRIYPV 307 L +R +L + + K + E+ + L + P Sbjct: 301 KTHPMNFLNER-TLKGTFFGNYKPK---TDIPGVVEKYMNK-----ELELEKFITHTVPF 351 Query: 308 TEIQEAHKYMEANKNI 323 +EI +A YM ++I Sbjct: 352 SEINKAFDYMLKGESI 367 >1E3J-A nrPDB Length = 352 Score = 141 bits (355), Expect = 4e-34, Method: Composition-based stats. Identities = 65/285 (22%), Positives = 110/285 (38%), Gaps = 44/285 (15%) Query: 3 AVHFDKPGGPENLYVKEVAKPSPGEGEVLLKVAASALNRADLM-QRQGQY-DPPPGASNI 60 AV + + +L +++ P P E EVLL++A + +D+ G+ D + Sbjct: 8 AVLYKQ----NDLRLEQRPIPEPKEDEVLLQMAYVGICGSDVHYYEHGRIADFIVKDPMV 63 Query: 61 LGLEASGHVAELGPGCQGHWKIGDTA--------------------------MALLP--G 92 +G EASG V ++G + H K GD P Sbjct: 64 IGHEASGTVVKVGKNVK-HLKKGDRVAVEPGVPCRRCQFCKEGKYNLCPDLTFCATPPDD 122 Query: 93 GGQAQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSG 152 G A+Y +P+ ++L + A + E G VQ G VL+ G Sbjct: 123 GNLARYYVHAADFCHKLPDNVSLEEGA-LLEPLSVGVHACRRAG-VQLGTTVLV-IGAGP 179 Query: 153 VGTAAIQLTRMAGAIPLVTAGSQKKLQMAEKLGAAA--GFNYKKEDFSEATLKFTKGAG- 209 +G ++ + GA + TA S ++L++A+ GA + KE+ S + G Sbjct: 180 IGLVSVLAAKAYGAFVVCTARSPRRLEVAKNCGADVTLVVDPAKEEESSIIERIRSAIGD 239 Query: 210 -VNLILDCIGG-SYWEKNVNCLALDGRWVLYGLMGGGDINGPLFS 252 N+ +DC G +N G +L G+ G + PL + Sbjct: 240 LPNVTIDCSGNEKCITIGINITRTGGTLMLVGM-GSQMVTVPLVN 283 >1E3E-A nrPDB Length = 376 Score = 140 bits (354), Expect = 5e-34, Method: Composition-based stats. Identities = 73/385 (18%), Positives = 127/385 (32%), Gaps = 74/385 (19%) Query: 2 LAVHFDKPGGPENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNIL 61 A K G P L ++E+ P EV ++V A+ + D+ +L Sbjct: 10 KAAIAWKTGSP--LCIEEIEVSPPKACEVRIQVIATCVCPTDINA--TDPKKKALFPVVL 65 Query: 62 GLEASGHVAELGPGCQGHWKIGDTAMALLPG----------------------------- 92 G E +G V +GPG ++K GD + Sbjct: 66 GHECAGIVESVGPGVT-NFKPGDKVIPFFAPQCKRCKLCLSPLTNLCGKLRNFKYPTIDQ 124 Query: 93 -----------------------GGQAQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAF 129 +QY V E L + + L + I + + + Sbjct: 125 ELMEDRTSRFTCKGRSIYHFMGVSSFSQYTVVSEANLARVDDEANLERVCLIGCGFSSGY 184 Query: 130 QLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGA-IPLVTAGSQKKLQMAEKLGAAA 188 V G + GL VG +AI ++AGA + + +K A+ LGA Sbjct: 185 GAAINTAKVTPGSTCAVF-GLGCVGLSAIIGCKIAGASRIIAIDINGEKFPKAKALGATD 243 Query: 189 GFNYKKED-FSEATLKFTKGAGVNLILDCIGGS-YWEKNVNCLALD-GRWVLYGLMGGGD 245 N ++ D + + GV+ LDC G + + V+C L G + G + Sbjct: 244 CLNPRELDKPVQDVITELTAGGVDYSLDCAGTAQTLKAAVDCTVLGWGSCTVVG-AKVDE 302 Query: 246 INGPLFSKLLFKRGSLITSLLRSRDNKYKQMLVNAFTEQILPHFSTEGPQRLLPVLDRIY 305 + P +L + S+ + K + N ++ F L ++ Sbjct: 303 MTIPTVDVILGR--SINGTFFG--GWKSVDSVPNLVSDYKNKKFD------LDLLVTHAL 352 Query: 306 PVTEIQEAHKYMEANKNIGKIVLEL 330 P I +A M+ K+I + +L Sbjct: 353 PFESINDAIDLMKEGKSI-RTILTF 376 >3FPL-A nrPDB Length = 351 Score = 140 bits (354), Expect = 6e-34, Method: Composition-based stats. Identities = 56/271 (20%), Positives = 97/271 (35%), Gaps = 40/271 (14%) Query: 11 GPENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQR-QGQYDPPPGASNILGLEASGHV 69 G L E +P G + +++ A + +D+ +G + ILG EA G V Sbjct: 8 GINKLGWIEKERPVAGSYDAIVRPLAVSPCTSDIHTVFEGALGD--RKNMILGHEAVGEV 65 Query: 70 AELGPGCQGHWKIGDTAM------------------------------ALLPGGGQAQY- 98 E+G + +K GD + + G +Y Sbjct: 66 VEVGSEVK-DFKPGDRVIVPCTTPDWRSLEVQAGFQQHSNGMLAGWKFSNFKDGVFGEYF 124 Query: 99 -VTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAA 157 V + L +P+ + L A I + T F L +++ G V + G+ VG A Sbjct: 125 HVNDADMNLAILPKDMPLENAVMITDMMTTGFHGAEL-ADIELGATVAVL-GIGPVGLMA 182 Query: 158 IQLTRMAGAIPLVTAGSQKKL-QMAEKLGAAAGFNYKKEDFSEATLKFTKGAGVNLILDC 216 + ++ GA ++ GS+ A+ GA NYK + T+G GV+ + Sbjct: 183 VAGAKLRGAGRIIAVGSRPVCVDAAKYYGATDIVNYKDGPIESQIMNLTEGKGVDAAIIA 242 Query: 217 IGGSYW-EKNVNCLALDGRWVLYGLMGGGDI 246 G + V + G G G++ Sbjct: 243 GGNADIMATAVKIVKPGGTIANVNYFGEGEV 273 >4DLA-A nrPDB Length = 396 Score = 140 bits (354), Expect = 6e-34, Method: Composition-based stats. Identities = 73/383 (19%), Positives = 127/383 (33%), Gaps = 70/383 (18%) Query: 2 LAVHFDKPGGPENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNIL 61 A +P P L +++V P GEV +KV +AL D G+ DP +L Sbjct: 28 KAAVAWEPNKP--LVIEDVQVAPPQAGEVRVKVLYTALCHTDAYTWSGK-DPEGLFPCVL 84 Query: 62 GLEASGHVAELGPGCQGHWKIGDTAMAL-------------------------------- 89 G EA+G V +G G + GD + Sbjct: 85 GHEAAGIVESVGEGVTE-VQPGDHVIPCYQAECRECKFCKSGKTNLCGKVRAATGVGVMM 143 Query: 90 -----------------LPGGGQAQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLL 132 + +QY V + + I L + + T + Sbjct: 144 NDRKSRFSINGKPIYHFMGTSTFSQYTVVHDVSVAKIDPVAPLEKVCLLGCGVPTGLGAV 203 Query: 133 HLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGA-IPLVTAGSQKKLQMAEKLGAAAGFN 191 V+ G V + GL VG A + + AGA + KK A+ G N Sbjct: 204 WNTAKVEPGSIVAVF-GLGTVGLAVAEGAKAAGASRIIGIDIDSKKFDRAKNFGVTEFIN 262 Query: 192 YK--KEDFSEATLKFTKGAGVNLILDCIGG-SYWEKNVNCLALD-GRWVLYGLMGGGDIN 247 K ++ + + T G GV+ +CIG S + C G V+ G+ G Sbjct: 263 PKEHEQPIQQVIVDLTDG-GVDYSFECIGNVSVMRSALECCHKGWGTSVIVGVAASGQEI 321 Query: 248 GPLFSKLLFKRGSLITSLLRSRDNKYKQMLVNAFTEQILPHFSTEGPQRLLPVLDRIYPV 307 +L+ R T+ + LV+ + ++ + ++ + + Sbjct: 322 STRPFQLVTGRVWKGTAFGGFKSRSQVPSLVDKYLKKEI---------KVDEYITHNMTL 372 Query: 308 TEIQEAHKYMEANKNIGKIVLEL 330 +I +A M + ++VL++ Sbjct: 373 ADINKAFDLMHDGDCL-RVVLDM 394 >2OUI-A nrPDB Length = 360 Score = 140 bits (354), Expect = 6e-34, Method: Composition-based stats. Identities = 70/357 (19%), Positives = 120/357 (33%), Gaps = 50/357 (14%) Query: 1 MLAVHFDKPGGPENLYVKEVAKPSPGEGEVLLKVAASALNRADLM-QRQGQYDPPPGASN 59 M + G + E P G + L++ A A +D G Sbjct: 1 MKGLAMLGIGR---IGWIEKKIPECGPLDALVRPLALAPCTSDTHTVWAGAIGDRHDM-- 55 Query: 60 ILGLEASGHVAELGPGCQGHWKIGDTAM--ALLPG------------------------- 92 ILG EA G + ++G + K+GD + A+ P Sbjct: 56 ILGHEAVGQIVKVGSLVK-RLKVGDKVIVPAITPDWGEEESQRGYPMHSGGMLGGWKFSN 114 Query: 93 ---GGQAQ--YVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIH 147 G ++ +V + L +P + A + + T F L N++ GD V + Sbjct: 115 FKDGVFSEVFHVNEADANLALLPRDIKPEDAVMLSDMVTTGFHGAEL-ANIKLGDTVCV- 172 Query: 148 AGLSGVGTAAIQLTRMAGAIPLVTAGSQKKL-QMAEKLGAAAGFNYKKEDFSEATLKFTK 206 G+ VG ++ GA + GS+K +A + GA NYK D E LK T Sbjct: 173 IGIGPVGLMSVAGANHLGAGRIFAVGSRKHCCDIALEYGATDIINYKNGDIVEQILKATD 232 Query: 207 GAGVNLILDCIGG-SYWEKNVNCLALDGRWVLYGLMGGGDINGPLFSKLLFKRGSLITSL 265 G GV+ ++ G + + V + +G GD N P+ R + Sbjct: 233 GKGVDKVVIAGGDVHTFAQAVKMIKPGSDIGNVNYLGEGD-NIPIP------RSEWGVGM 285 Query: 266 LRSRDNKYKQMLVNAFTEQILPHFSTEGPQRLLPVLDRIYPVTEIQEAHKYMEANKN 322 + E++ ST + R + ++++A M+ Sbjct: 286 GHKHIHGGLTPGGRVRMEKLASLISTGKLDTSKLITHRFEGLEKVEDALMLMKNKPA 342 >1EE2-A nrPDB Length = 373 Score = 139 bits (349), Expect = 2e-33, Method: Composition-based stats. Identities = 69/369 (18%), Positives = 124/369 (33%), Gaps = 65/369 (17%) Query: 13 ENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNILGLEASGHVAEL 72 + ++EV P EV +K+ A+ + R+D G P I G EA+G V + Sbjct: 19 KPFSIEEVEVAPPKAHEVRIKMVAAGICRSDDHVVSGTLVAP--LPVIAGHEAAGIVESI 76 Query: 73 GPGCQGHWKIGDTAMA-LLPGGG------------------------------------- 94 G G + GD + +P G Sbjct: 77 GEGVTT-VRPGDKVIPLFIPQCGKCSVCKHPEGNLCLKNLSMPRGTMQDGTSRFTCRGKP 135 Query: 95 ---------QAQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVL 145 +QY V E + I L + + + T + V V G Sbjct: 136 IHHFLGTSTFSQYTVVDEISVAKIDAASPLEKVCLVGCGFSTGYGSAVKVAKVTQGSTCA 195 Query: 146 IHAGLSGVGTAAIQLTRMAGA-IPLVTAGSQKKLQMAEKLGAAAGFNYKK-EDFSEATLK 203 + GL GVG + I + AGA + ++ K A+++GA N + + + L Sbjct: 196 VF-GLGGVGLSVIMGCKAAGAARIIGVDINKDKFAKAKEVGATECVNPQDYKKPIQEVLT 254 Query: 204 FTKGAGVNLILDCIGG-SYWEKNVNCLALD-GRWVLYGLMGGGDINGPLFSKLLFKRGSL 261 GV+ + IG ++C G V+ G+ N + LL + Sbjct: 255 EMSNGGVDFSFEVIGRLDTMVAALSCCQEAYGVSVIVGVPPDSQ-NLSMNPMLLLSGRTW 313 Query: 262 ITSLLRSRDNKYKQMLVNAFTEQILPHFSTEGPQRLLPVLDRIYPVTEIQEAHKYMEANK 321 ++ +K + + + F+ L P++ + P +I E + + K Sbjct: 314 KGAIFGGFKSK--DSVPKLVADFMAKKFA------LDPLITHVLPFEKINEGFDLLRSGK 365 Query: 322 NIGKIVLEL 330 +I + +L Sbjct: 366 SI-RTILTF 373 >5YLN-A nrPDB Length = 356 Score = 139 bits (349), Expect = 2e-33, Method: Composition-based stats. Identities = 74/364 (20%), Positives = 135/364 (37%), Gaps = 53/364 (14%) Query: 1 MLAVHFDKPGGPENLYVKEVAKPSP-GEGEVLLKVAASALNRADLMQRQGQYDPPPGASN 59 M A + KPG +V KP + ++++ + + DL +G P + Sbjct: 5 MKAYTYVKPGLA---SFVDVDKPVIRKPTDAIVRIVKTTICGTDLHIIKGDV-PTCQSGT 60 Query: 60 ILGLEASGHVAELGPGCQGHWKIGDTAM-----------------------------ALL 90 ILG E G V E+G G ++K GD + L Sbjct: 61 ILGHEGIGIVEEVGEGVS-NFKKGDKVLISCVCACGKCYYCKKGIYAHCEDEGGWIFGHL 119 Query: 91 PGGGQAQYVTVPE--GLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHA 148 G QA+Y+ VP L PE L+ + + T +++ L G V+ G V I Sbjct: 120 IDGMQAEYLRVPHADNTLYHTPEDLSDEALVMLSDILPTGYEIGVLKGKVEPGCSVAI-I 178 Query: 149 GLSGVGTAAIQLTRMAG-AIPLVTAGSQKKLQMAEKLGAAAGFNYKKED-FSEATLKFTK 206 G VG AA+ + A ++ +L+ A GA N + + T Sbjct: 179 GSGPVGLAALLTAQFYSPAKLIMVDLDDNRLETALSFGATHKVNSSDPEKAIKEIYDLTD 238 Query: 207 GAGVNLILDCIG-GSYWEKNVNCLALDGRWVLYGLMGGGDINGPLFSKLLFKRGSLITSL 265 G GV++ ++ +G + ++ + +DG G+ G KL + ++ T L Sbjct: 239 GRGVDVAIEAVGIPATFDFCQKIIGVDGTVANCGVHGKP--VEFDLDKLWIRNINVTTGL 296 Query: 266 LRSRDNKYKQMLVNAFTEQILPHFSTEGPQRLLPVLDRIYPVTEIQEAHKYMEANKNIGK 325 + + L+ A + P++L+ ++ + + E + I K Sbjct: 297 VSTNT---TPQLLKALESHKIE------PEKLVTHYFKLSEIEKAYEVFSKAADHHAI-K 346 Query: 326 IVLE 329 +++E Sbjct: 347 VIIE 350 >1D1T-A nrPDB Length = 373 Score = 137 bits (346), Expect = 5e-33, Method: Composition-based stats. Identities = 69/371 (18%), Positives = 122/371 (32%), Gaps = 69/371 (18%) Query: 13 ENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNILGLEASGHVAEL 72 + ++E+ P EV +K+ A+ + R D +G I+G EA+G V + Sbjct: 19 QPFSIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGTMVSK--FPVIVGHEATGIVESI 76 Query: 73 GPGCQGHWKIGDTAMALL------------PGG--------------------------- 93 G G K GD + L P G Sbjct: 77 GEGVTT-VKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDITGRGVLADGTTRFTCKGKP 135 Query: 94 --------GQAQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVL 145 +Y V E + I + + I + T + G V+ G + Sbjct: 136 VHHFLNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTGKVKPGSTCV 195 Query: 146 IHAGLSGVGTAAIQLTRMAGA-IPLVTAGSQKKLQMAEKLGAAAGFNYK-KEDFSEATLK 203 + GL GVG + I + AGA + ++ K + A +GA + K L Sbjct: 196 VF-GLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKDSTKPISEVLS 254 Query: 204 FTKGAGVNLILDCIGGSYWEKNVNCLA----LDGRWVLYGLMGGGDINGPLFSKLLFKRG 259 G V + IG + E ++ LA G V+ G+ + + +L G Sbjct: 255 EMTGNNVGYTFEVIG--HLETMIDALASCHMNYGTSVVVGVPPSAKM--LTYDPMLLFTG 310 Query: 260 SLITSLLRSRDNKYKQMLVNAFTEQILPHFSTEGPQRLLPVLDRIYPVTEIQEAHKYMEA 319 + + + TE + F L ++ + P +I E + + + Sbjct: 311 RTWKGCVFGGLKS-RDDVPKLVTEFLAKKFD------LDQLITHVLPFKKISEGFELLNS 363 Query: 320 NKNIGKIVLEL 330 ++I + VL Sbjct: 364 GQSI-RTVLTF 373 >4JJI-A nrPDB Length = 378 Score = 136 bits (342), Expect = 2e-32, Method: Composition-based stats. Identities = 77/385 (20%), Positives = 125/385 (32%), Gaps = 70/385 (18%) Query: 2 LAVHFDKPGGPENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNIL 61 A +P P L +++V P GEV +K+ +AL D G+ DP IL Sbjct: 10 KAAVAYEPNKP--LVIEDVQVAPPQAGEVRIKILYTALCHTDAYTWSGK-DPEGLFPCIL 66 Query: 62 GLEASGHVAELGPGCQGHWKIGDTAMAL-------------------------------- 89 G EA+G V +G G + GD + Sbjct: 67 GHEAAGIVESVGEGVTE-VQAGDHVIPCYQAECRECKFCKSGKTNLCGKVRSATGVGIMM 125 Query: 90 -----------------LPGGGQAQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLL 132 + +QY V + + I L + + T + Sbjct: 126 NDRKSRFSVNGKPIYHFMGTSTFSQYTVVHDVSVAKIDPTAPLDKVCLLGCGVPTGLGAV 185 Query: 133 HLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGA-IPLVTAGSQKKLQMAEKLGAAAGFN 191 V+ G V I GL VG A + + AGA + KK + A+K G N Sbjct: 186 WNTAKVEPGSNVAIF-GLGTVGLAVAEGAKTAGASRIIGIDIDSKKYETAKKFGVNEFVN 244 Query: 192 YKKED--FSEATLKFTKGAGVNLILDCIGG-SYWEKNVNCLALD-GRWVLYGLMGGGDIN 247 K D E + T G GV+ +CIG S + C G V+ G+ G Sbjct: 245 PKDHDKPIQEVIVDLTDG-GVDYSFECIGNVSVMRAALECCHKGWGTSVIVGVAASGQEI 303 Query: 248 GPLFSKLLFKRGSLITSLLRSRDNKYKQMLVNAFTEQILPHFSTEGPQRLLPVLDRIYPV 307 +L+ R T+ + LV + + + ++ + + Sbjct: 304 STRPFQLVTGRVWKGTAFGGFKSRTQVPWLVEKYMNKEI---------KVDEYITHNLTL 354 Query: 308 TEIQEAHKYMEANKNIGKIVLELPQ 332 EI +A + + + VL+ + Sbjct: 355 GEINKAFDLLHEGTCL-RCVLDTSK 378 >1CDO-A nrPDB Length = 374 Score = 135 bits (340), Expect = 2e-32, Method: Composition-based stats. Identities = 74/373 (19%), Positives = 126/373 (33%), Gaps = 72/373 (19%) Query: 13 ENLYVKEVAKPSPGEGEVLLKVAASALNRADL-MQRQGQYDPPPGASNILGLEASGHVAE 71 + L ++E+ P E+ +K+ A+ + DL +G++ G +LG E +G V Sbjct: 19 KPLVIEEIEVDVPHANEIRIKIIATGVCHTDLYHLFEGKH--KDGFPVVLGHEGAGIVES 76 Query: 72 LGPGCQGHWKIGDTAMA-LLPGGG------------------------------------ 94 +GPG ++ G+ + + G Sbjct: 77 VGPGVTE-FQPGEKVIPLFISQCGECRFCQSPKTNQCVKGWANESPDVMSPKETRFTCKG 135 Query: 95 -----------QAQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDY 143 +QY V + + I L + T F V+ G Sbjct: 136 RKVLQFLGTSTFSQYTVVNQIAVAKIDPSAPLDTVCLLGCGVSTGFGAAVNTAKVEPGST 195 Query: 144 VLIHAGLSGVGTAAIQLTRMAGA-IPLVTAGSQKKLQMAEKLGAAAGFNY--KKEDFSEA 200 + GL VG AA+ AGA + + K + A+ GA N E S+ Sbjct: 196 CAVF-GLGAVGLAAVMGCHSAGAKRIIAVDLNPDKFEKAKVFGATDFVNPNDHSEPISQV 254 Query: 201 TLKFTKGAGVNLILDCIG--GSYWEKNVNCLALDGRWVLYGLMGGGDINGPLFSKLLFKR 258 K T G GV+ L+C+G G +CL G VL G D+ + + Sbjct: 255 LSKMTNG-GVDFSLECVGNVGVMRNALESCLKGWGVSVLVGWTDLHDVATRPIQLIAGR- 312 Query: 259 GSLITSLLRSRDNK-YKQMLVNAFTEQILPHFSTEGPQRLLPVLDRIYPVTEIQEAHKYM 317 + S+ K +V A+ ++ +L + P+ + +A M Sbjct: 313 -TWKGSMFGGFKGKDGVPKMVKAYLDK---------KVKLDEFITHRMPLESVNDAIDLM 362 Query: 318 EANKNIGKIVLEL 330 + K I + VL L Sbjct: 363 KHGKCI-RTVLSL 374 >4ILK-A nrPDB Length = 359 Score = 134 bits (336), Expect = 8e-32, Method: Composition-based stats. Identities = 69/362 (19%), Positives = 134/362 (37%), Gaps = 53/362 (14%) Query: 1 MLAVHFDKPGGPENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNI 60 M ++ +K P L + E P+P GEV +KV + + +D +G ++P + Sbjct: 21 MKSILIEK---PNQLSIIEREIPTPSAGEVRVKVKLAGICGSDSHIYRG-HNPFAKYPRV 76 Query: 61 LGLEASGHVAELGPGCQ----------------GHWKIGDT----------AMALLPGGG 94 +G E G + +G G + GH + + GG Sbjct: 77 IGHEFFGVIDAVGEGVESARVGERVAVDPVVSCGHCYPCSIGKPNVCTTLAVLGVHADGG 136 Query: 95 QAQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVG 154 ++Y VP IPE + A I + A H G D VL++ G +G Sbjct: 137 FSEYAVVPAKNAWKIPEAVADQYAVMIEPFTIAANVTGH--GQPTENDTVLVY-GAGPIG 193 Query: 155 TAAIQLTR-MAGAI-PLVTAGSQKKLQMAEKLGAAAGFNYKKEDFSEATLKFTKGAGVNL 212 +Q+ + + +V ++L+ A++ GA N + E+ + KG L Sbjct: 194 LTIVQVLKGVYNVKNVIVADRIDERLEKAKESGADWAINNSQTPLGESFAE--KGIKPTL 251 Query: 213 ILDCIG-GSYWEKNVNCLALDGRWVLYGLMGGGDINGPLFSKLLFKRGSLITSLLRSRDN 271 I+D S ++ V + R VL G + + + + K S+ +S L + Sbjct: 252 IIDAACHPSILKEAVTLASPAARIVLMGFSS--EPSEVIQQGITGKELSIFSSRLNANKF 309 Query: 272 KYKQMLVNAFTEQILPHFSTEGPQRLLPVLDRIYPVTEIQEAHKYME-ANKNIGKIVLEL 330 ++ + ++G + ++ + + +A E K+ K++L Sbjct: 310 ------------PVVIDWLSKGLIKPEKLITHTFDFQHVADAISLFELDQKHCCKVLLTF 357 Query: 331 PQ 332 + Sbjct: 358 SE 359 >1UUF-A nrPDB Length = 369 Score = 133 bits (335), Expect = 9e-32, Method: Composition-based stats. Identities = 64/356 (17%), Positives = 123/356 (34%), Gaps = 64/356 (17%) Query: 13 ENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNILGLEASGHVAEL 72 + L ++ + PG +V +++A + +DL Q + ++ + G E G V + Sbjct: 33 QPLEPMDITRREPGPNDVKIEIAYCGVCHSDLHQVRSEWAG-TVYPCVPGHEIVGRVVAV 91 Query: 73 GPGCQGHWKIGDTA-MALLPG-----------------------------------GGQA 96 G + + GD + + GG + Sbjct: 92 GDQVE-KYAPGDLVGVGCIVDSCKHCEECEDGLENYCDHMTGTYNSPTPDEPGHTLGGYS 150 Query: 97 QYVTVPEGLLMPI--PEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVG 154 Q + V E ++ I P+ L A + A +T + L ++ G +G Sbjct: 151 QQIVVHERYVLRIRHPQE-QLAAVAPLLCAGITTYSPLRHWQAGPGKKVGVVGIGG--LG 207 Query: 155 TAAIQLTRMAGAIPLVTAGSQKKLQMAEKLGAAAGFNYKKEDFSEATLKFTKGAGVNLIL 214 I+L GA + S+ K + A+ LGA N + D A LK + IL Sbjct: 208 HMGIKLAHAMGAHVVAFTTSEAKREAAKALGADEVVNSRNADEMAAHLKS-----FDFIL 262 Query: 215 DCIGGS-YWEKNVNCLALDGRWVLYGLMGGGDINGPLFSKLLFKRGSLITSLLRSRDNKY 273 + + + L DG L G + P L+ KR ++ S++ Sbjct: 263 NTVAAPHNLDDFTTLLKRDGTMTLVGAPATPHKS-PEVFNLIMKRRAIAGSMIGGI---- 317 Query: 274 KQMLVNAFTEQILPHFSTEGPQRLLPVLDRIYPVTEIQEAHKYMEANKNIGKIVLE 329 T+++L + G + ++ +I EA++ M + V++ Sbjct: 318 ------PETQEMLDFCAEHGIVADIEMIRA----DQINEAYERMLRGDVKYRFVID 363 >3WLE-A nrPDB Length = 341 Score = 130 bits (327), Expect = 9e-31, Method: Composition-based stats. Identities = 67/343 (19%), Positives = 122/343 (35%), Gaps = 60/343 (17%) Query: 19 EVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNILGLEASGHVAELGPGCQG 78 ++ P G++LLKV A L +DL G + ++G E +G VA +G Sbjct: 28 DLPVHKPKAGQLLLKVDAVGLCHSDLHVIY--EGLDCGDNYVMGHEIAGTVAAVGDDV-I 84 Query: 79 HWKIGDTAMALLP-----------------------------GGGQAQYVTV-PEGLLMP 108 ++K+GD + P GG QY+ V L Sbjct: 85 NYKVGDRVACVGPNGCGGCKYCRGAIDNVCKNAFGDWFGLGYDGGYQQYLLVTRPRNLSR 144 Query: 109 IPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIP 168 IP+ ++ AAA +A LT + + + V +L+ G+G AIQ+ + GA Sbjct: 145 IPDNVSADVAAASTDAVLTPYHAIKM-AQVSPTSNILLIGAG-GLGGNAIQVAKAFGAKV 202 Query: 169 LVTAGSQKKLQMAEKLGAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIG-GSYWEKNVN 227 V ++ A+KLGA A + E + + D + + ++ Sbjct: 203 TVLDKKKEARDQAKKLGADAVY--------ETLPESISPGSFSACFDFVSVQATFDVCQK 254 Query: 228 CLALDGRWVLYGLMGGGDINGPLFSKLLFKRGSLITSLLRSRDNKYKQMLVNAFTEQILP 287 + G + GL G L + ++ S + ++ + Sbjct: 255 YVEPKGVIMPVGL--GAPNLSFNLGDLALREIRILGSFWGTTND-------------LDD 299 Query: 288 HFSTEGPQRLLPVLDRIYPVTEIQEAHKYMEANKNIGKIVLEL 330 ++ PV+ R + E+ E + + N G++V Sbjct: 300 VLKLVSEGKVKPVV-RSAKLKELPEYIEKLRNNAYEGRVVFNP 341 >1P0F-A nrPDB Length = 373 Score = 130 bits (326), Expect = 9e-31, Method: Composition-based stats. Identities = 79/382 (20%), Positives = 132/382 (34%), Gaps = 75/382 (19%) Query: 2 LAVHFDKPGGPENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNIL 61 A +P P L ++ + P EV +K+ AS + +D + P IL Sbjct: 11 KAAVAWEPHKP--LSLETITVAPPKAHEVRIKILASGICGSDSSVLKEII--PSKFPVIL 66 Query: 62 GLEASGHVAELGPGCQGHWKIGDTAMALL-PGGG-------------------------- 94 G EA G V +G G K GD + L P G Sbjct: 67 GHEAVGVVESIGAGVTC-VKPGDKVIPLFVPQCGSCRACKSSNSNFCEKNDMGAKTGLMA 125 Query: 95 ---------------------QAQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLH 133 +Y V + + I L ++ I + T + Sbjct: 126 DMTSRFTCRGKPIYNLMGTSTFTEYTVVADIAVAKIDPKAPL-ESCLIGCGFATGYGAAV 184 Query: 134 LVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGS-QKKLQMAEKLGAAAGFNY 192 V G + GL GVG +AI + AGA ++ G+ + K A +LGA N Sbjct: 185 NTAKVTPGSTCAVF-GLGGVGFSAIVGCKAAGASRIIGVGTHKDKFPKAIELGATECLNP 243 Query: 193 KKED--FSEATLKFTKGAGVNLILDCIGGSYWEKNVNCLALD----GRWVLYGLMGGGDI 246 K D E + T G GV+ ++C G E +N L G V+ GL + Sbjct: 244 KDYDKPIYEVICEKTNG-GVDYAVECAGR--IETMMNALQSTYCGSGVTVVLGLASPNER 300 Query: 247 NGPLFSKLLFKRGSLITSLLRSRDNKYKQMLVNAFTEQILPHFSTEGPQRLLPVLDRIYP 306 LL R SL S+ + LV+ + ++ + + ++ Sbjct: 301 LPLDPLLLLTGR-SLKGSVFGGFKGEEVSRLVDDYMKKKIN---------VNFLVSTKLT 350 Query: 307 VTEIQEAHKYMEANKNIGKIVL 328 + +I +A + + + + + I++ Sbjct: 351 LDQINKAFELLSSGQGVRSIMI 372 >4OAQ-A nrPDB Length = 367 Score = 129 bits (323), Expect = 2e-30, Method: Composition-based stats. Identities = 66/345 (19%), Positives = 115/345 (33%), Gaps = 61/345 (17%) Query: 27 EGEVLLKVAASALNRADLMQRQGQYDPPPGASNILGLEASGHVAELGPGCQGHWKIGDTA 86 +V+LK L +D+ + P + ++G E G V +G +K+GD Sbjct: 35 PHDVVLKNEVCGLCYSDIHTLSAGWQPLQRDNLVVGHEIIGEVIAVGDEVTE-FKVGDRV 93 Query: 87 -------------------------------------MALLPGGGQAQYVTVPEGLLMPI 109 + GG + + E + I Sbjct: 94 GIGAASSSCRSCQRCDSDNEQYCKQGAATYNSKDVRSNNYVTQGGYSSHSIADEKFVFAI 153 Query: 110 PEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPL 169 PE L + A + A +T F L + A + G+ G+G A+Q GA Sbjct: 154 PEDLPSSYGAPLMCAGITVFSPLIRNLGLDARGKNVGIIGIGGLGHLALQFANAMGANVT 213 Query: 170 VTAGSQKKLQMAEKLGAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIGGS---YWEKNV 226 + S K + A KLGA ED + K + IL+C G + + Sbjct: 214 AFSRSSSKKEQAMKLGAHDFV-ATGED--KTWYKNYD-DHFDFILNCASGIDGLNLSEYL 269 Query: 227 NCLALDGRWVLYGLMGGGDINGPLFSKLLFKRGSLITSLLRSRDNKYKQMLVNAFTEQIL 286 + L +D ++V GL D L + S +SLL S+ ++ Sbjct: 270 STLKVDKKFVSVGLPPSEDKFEVSPFTFLQQGASFGSSLLGSKT-------------EVK 316 Query: 287 PHFSTEGPQRLLPVLDRIYPVTEIQ--EAHKYMEANKNIGKIVLE 329 + + P+++ + P++E +A A + V Sbjct: 317 EMLNLAAKHNVRPMIEEV-PISEENCAKALDRCHAGDVRYRFVFT 360 >1Q1N-A nrPDB Length = 360 Score = 125 bits (315), Expect = 2e-29, Method: Composition-based stats. Identities = 67/348 (19%), Positives = 114/348 (32%), Gaps = 64/348 (18%) Query: 22 KPSP-GEGEVLLKVAASALNRADLMQRQGQYDPPPGASNILGLEASGHVAELGPGCQGHW 80 P P + ++ +K+ A + +D+ G + ++G E G V +LGP Sbjct: 27 DPKPFYDHDIDIKIEACGVCGSDIHCAAGHWGN-MKMPLVVGHEIVGKVVKLGPKSNSGL 85 Query: 81 KIGDTA-----------------------------------MALLPGGGQAQYVTVPEGL 105 K+G + GG A YV V E Sbjct: 86 KVGQRVGVGAQVFSCLECDRCKNDNEPYCTKFVTTYSQPYEDGYVSQGGYANYVRVHEHF 145 Query: 106 LMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAG 165 ++PIPE + AA + LT + L G ++ G +G+ +++ G Sbjct: 146 VVPIPENIPSHLAAPLLCGGLTVYSPLVRNGCGPGKKVGIVGLGG--IGSMGTLISKAMG 203 Query: 166 AIPLVTAGSQKKLQMAEKLGAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIGGSY---W 222 A V + S +K + A K+GA +E T +LI+ C + Sbjct: 204 AETYVISRSSRKREDAMKMGADHYIATLEEGDWGEKYFDT----FDLIVVCASSLTDIDF 259 Query: 223 EKNVNCLALDGRWVLYGLMGGGDINGPLFSKLLFKRGSLITSLLRSRDNKYKQMLVNAFT 282 + + GR V + ++ K S+ S L S K L+ + Sbjct: 260 NIMPKAMKVGGRIVSISIPEQHEM--LSLKPYGLKAVSISYSALGSI--KELNQLLKLVS 315 Query: 283 EQILPHFSTEGPQRLLPVLDRIYPVTEI--QEAHKYMEANKNIGKIVL 328 E+ + + PV E EA + ME + L Sbjct: 316 EKDIKIWV------------ETLPVGEAGVHEAFERMEKGDVRYRFTL 351 >2VNA-A nrPDB Length = 357 Score = 125 bits (313), Expect = 3e-29, Method: Composition-based stats. Identities = 66/352 (18%), Positives = 129/352 (36%), Gaps = 30/352 (8%) Query: 2 LAVHFDKPGG-----PENLYVKEVAKP-SPGEGEVLLKVAASALNRADLMQR-------Q 48 V +PG EN ++EV P + EG+V ++ ++ D R Sbjct: 6 RVVLNSRPGKNGNPVAENFRMEEVYLPDNINEGQVQVRTLYLSV---DPYMRCRMNEDTG 62 Query: 49 GQYDPPPGASNILGLEASGHVAELGPGCQGHWKIGDTAMALLPGGGQAQYVTVPEGLLMP 108 Y P S ++ G + E + GD + V + L Sbjct: 63 TDYITPWQLSQVVDGGGIGIIEE---SKHTNLTKGDFVTSFYWP--WQTKVILDGNSLEK 117 Query: 109 I-PEGLTLTQA---AAIPEAWLTAFQLLHLVGNVQAG--DYVLIHAGLSGVGTAAIQLTR 162 + P+ + + AI LT+ + G++ AG +++ G+ A Q+ Sbjct: 118 VDPQLVDGHLSYFLGAIGMPGLTSLIGIQEKGHITAGSNKTMVVSGAAGACGSVAGQIGH 177 Query: 163 MAGA-IPLVTAGSQKKLQMAE-KLGAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIGGS 220 G + G+ +K + +LG A NYKK++ +E + AGV++ D +GG+ Sbjct: 178 FLGCSRVVGICGTHEKCILLTSELGFDAAINYKKDNVAEQLRESC-PAGVDVYFDNVGGN 236 Query: 221 YWEKNVNCLALDGRWVLYGLMGGGDINGPLFSKLLFKRGSLITSLLRSRDNKYKQMLVNA 280 + ++ + + +L G + + + P L ++ +R+ + Sbjct: 237 ISDTVISQMNENSHIILCGQISQYNKDVPYPPPLSPAIEAIQKERNITRERFLVLNYKDK 296 Query: 281 FTEQILPHFSTEGPQRLLPVLDRIYPVTEIQEAHKYMEANKNIGKIVLELPQ 332 F IL +L I + + A + M NIGK ++ + + Sbjct: 297 FEPGILQLSQWFKEGKLKIKETVINGLENMGAAFQSMMTGGNIGKQIVCISE 348 >4UEJ-A nrPDB Length = 346 Score = 124 bits (311), Expect = 6e-29, Method: Composition-based stats. Identities = 75/361 (20%), Positives = 120/361 (33%), Gaps = 50/361 (13%) Query: 1 MLAVHFDKPGGPENLYVKEVAKPSPGE-GEVLLKVAASALNRADL--MQRQGQYDPPPGA 57 M +V D G + V E P EV +K+A+S L +DL + + G + Sbjct: 1 MKSVVNDTDG---IVRVAESVIPEIKHQDEVRVKIASSGLCGSDLPRIFKNGAH----YY 53 Query: 58 SNILGLEASGHVAELGPGCQGHWKIGDTA---------------------------MALL 90 LG E SG++ +G G GD + Sbjct: 54 PITLGHEFSGYIDAVGSGV-DDLHPGDAVACVPLLPCFTCPECLKGFYSQCAKYDFIGSR 112 Query: 91 PGGGQAQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGL 150 GG A+Y+ V + +P + + A E HL + + ++I G Sbjct: 113 RDGGFAEYIVVKRKNVFALPTDMPIEDGA-FIEPITVGLHAFHLAQGCENKNVIII--GA 169 Query: 151 SGVGTAAIQLTRMAGAI-PLVTAGSQKKLQMAEKLGAAAGFNYKKEDFSEATLKFTKGAG 209 +G AIQ GA S +KL +A+ GA FN + + + Sbjct: 170 GTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRF 229 Query: 210 VNLILDCIG-GSYWEKNVNCLALDGRWVLYG-LMGGGDINGPLFSKLLFKRGSLITSLLR 267 LIL+ G E V + L G L + F K+L K ++I S + Sbjct: 230 NQLILETAGVPQTVELAVEIAGPHAQLALVGTLHQDLHLTSATFGKILRKELTVIGSWMN 289 Query: 268 SRDNKYKQMLVNAFTEQILPHFSTEGPQRLLPVLDRIYPVTEIQEAHKYMEANKNIGKIV 327 + TE L P++ +A + + N GK++ Sbjct: 290 ------YSSPWPGQEWETASRLLTERKLSLEPLIAHRGSFESFAQAVRDIARNAMPGKVL 343 Query: 328 L 328 L Sbjct: 344 L 344 >3TWO-A nrPDB Length = 348 Score = 122 bits (306), Expect = 2e-28, Method: Composition-based stats. Identities = 61/346 (17%), Positives = 119/346 (34%), Gaps = 67/346 (19%) Query: 26 GEGEVLLKVAASALNRADLMQRQGQYDPPPGASNILGLEASGHVAELGPGCQGHWKIGDT 85 G +VL+ + + + +D+ ++ I G E +G + E+G G + +KIGD Sbjct: 28 GPRDVLIDILYAGICHSDIHSAYSEWK-EGIYPMIPGHEIAGIIKEVGKGVK-KFKIGDV 85 Query: 86 A-MALLPG------------------------------------GGQAQYVTVPEGLLMP 108 + GG + + V E ++ Sbjct: 86 VGVGCFVNSCKACKPCKEHQEQFCTKVVFTYDCLDSFHDNEPHMGGYSNNIVVDENYVIS 145 Query: 109 IPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIP 168 + + L + A + A +T + L V G V + AG G+G+ A++ GA Sbjct: 146 VDKNAPLEKVAPLLCAGITTYSPLK-FSKVTKGTKVGV-AGFGGLGSMAVKYAVAMGAEV 203 Query: 169 LVTAGSQKKLQMAEKLGAAAGF-NYKKEDFSEATLKFTKGAGVNLILDCIGGSYWEKNVN 227 V A ++ K Q A +G + + K+ + T +L + + Sbjct: 204 SVFARNEHKKQDALSMGVKHFYTDPKQCKEELDFIISTIPTHYDL----------KDYLK 253 Query: 228 CLALDGRWVLYGLMGGGDIN-GPLFSKLLFKRGSLITSLLRSRDNKYKQMLVNAFTEQIL 286 L +G L GL +F + + SL+ K Q +V+ + Sbjct: 254 LLTYNGDLALVGLPPVEVAPVLSVFDFIHLGNRKVYGSLIGGI--KETQEMVDFSIKH-- 309 Query: 287 PHFSTEGPQRLLPVLDRIYPVTEIQEAHKYMEANKNIGKIVLELPQ 332 + P +D I +I A+ + K + V+++ + Sbjct: 310 ---------NIYPEIDLILG-KDIDTAYHNLTHGKAKFRYVIDMKK 345 >1YQX-A nrPDB Length = 366 Score = 121 bits (303), Expect = 5e-28, Method: Composition-based stats. Identities = 53/342 (15%), Positives = 113/342 (33%), Gaps = 61/342 (17%) Query: 26 GEGEVLLKVAASALNRADLMQRQGQYDPPPGASNILGLEASGHVAELGPGCQGHWKIGDT 85 GE +V KV + +DL + + + G E G V E+G + +GD Sbjct: 40 GEEDVRFKVLYCGVCHSDLHSIKNDWGF-SMYPLVPGHEIVGEVTEVGSKVK-KVNVGDK 97 Query: 86 A-----------------------------------MALLPGGGQAQYVTVPEGLLMPIP 110 + GG + ++ E ++ P Sbjct: 98 VGVGCLVGACHSCESCANDLENYCPKMILTYASIYHDGTITYGGYSNHMVANERYIIRFP 157 Query: 111 EGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLV 170 + + L A + A +T + L G + G ++ I A++ + G+ V Sbjct: 158 DNMPLDGGAPLLCAGITVYSPLKYFGLDEPGKHIGIVGLGGLG-HVAVKFAKAFGSKVTV 216 Query: 171 TAGSQ-KKLQMAEKLGAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIGGSY-WEKNVNC 228 + S KK + + GA + + ++ +A G I+D + + Sbjct: 217 ISTSPSKKEEALKNFGADSFLVSRDQEQMQAAAGTLDG-----IIDTVSAVHPLLPLFGL 271 Query: 229 LALDGRWVLYGLMGGGDINGPLFSKLLFKRGSLITSLLRSRDNKYKQMLVNAFTEQILPH 288 L G+ +L G + P FS + ++ + S + T++++ Sbjct: 272 LKSHGKLILVGAPEK-PLELPAFSLIAGRKI-VAGSGIGGMKE----------TQEMIDF 319 Query: 289 FSTEGPQRLLPVLDRIYPVTEIQEAHKYMEANKNIGKIVLEL 330 + + V+ Y + A + + N + V+++ Sbjct: 320 AAKHNITADIEVISTDY----LNTAMERLAKNDVRYRFVIDV 357 >2ZB3-A nrPDB Length = 353 Score = 118 bits (296), Expect = 3e-27, Method: Composition-based stats. Identities = 64/352 (18%), Positives = 123/352 (34%), Gaps = 30/352 (8%) Query: 2 LAVHFDKPGG-----PENLYVKEVAKP-SPGEGEVLLKVAASALNRADLMQR-------Q 48 V +PG EN V+E + P + EG+V ++ ++ D R Sbjct: 7 RVVLNSRPGKNGNTVAENFRVEEFSLPDALNEGQVQVRTLYLSV---DPYMRCKMNEDTG 63 Query: 49 GQYDPPPGASNILGLEASGHVAELGPGCQGHWKIGDTAMALLPGGGQAQYVTVPEGLLMP 108 Y P + + G V E GD + + L Sbjct: 64 TDYLAPWQLAQVADGGGIGVVEE---SKHQKLTKGDFVTSFYWP--WQTKAILDGNGLEK 118 Query: 109 I-PEGLTLTQA---AAIPEAWLTAFQLLHLVGNVQAG--DYVLIHAGLSGVGTAAIQLTR 162 + P+ + + AI LT+ + G++ AG +++ G+ A Q+ Sbjct: 119 VDPQLVDGHLSYFLGAIGMPGLTSLIGVQEKGHISAGSNQTMVVSGAAGACGSLAGQIGH 178 Query: 163 MAGA-IPLVTAGSQKK-LQMAEKLGAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIGGS 220 + G + G+Q+K L + +LG A NYK + +E + G GV++ D +GG Sbjct: 179 LLGCSRVVGICGTQEKCLFLTSELGFDAAVNYKTGNVAEQLREACPG-GVDVYFDNVGGD 237 Query: 221 YWEKNVNCLALDGRWVLYGLMGGGDINGPLFSKLLFKRGSLITSLLRSRDNKYKQMLVNA 280 ++ + + +L G + + P L ++ +R+ + Sbjct: 238 ISNAVISQMNENSHIILCGQISQYSNDVPYPPPLPPAVEAIRKERNITRERFTVLNYKDK 297 Query: 281 FTEQILPHFSTEGPQRLLPVLDRIYPVTEIQEAHKYMEANKNIGKIVLELPQ 332 F IL +L + + A + M N+GK ++ + + Sbjct: 298 FEPGILQLSQWFKEGKLKVKETMAKGLENMGVAFQSMMTGGNVGKQIVCISE 349 >5Z0C-A nrPDB Length = 374 Score = 118 bits (296), Expect = 3e-27, Method: Composition-based stats. Identities = 63/342 (18%), Positives = 122/342 (35%), Gaps = 61/342 (17%) Query: 26 GEGEVLLKVAASALNRADLMQRQGQYDPPPGASNILGLEASGHVAELGPGCQGHWKIGDT 85 GE +V KV + +DL + ++ + G E G V E+G +K+GD Sbjct: 37 GELDVTFKVLYCGICHSDLHYIKNEWSN-TIYPALPGHEIVGEVTEVGSKVN-KFKVGDK 94 Query: 86 A-----------------------------------MALLPGGGQAQYVTVPEGLLMPIP 110 L GG + + V E + IP Sbjct: 95 VGVGCIVGSCHSCPNCNNHLENYCPNRILTFGSRYYDGTLNHGGYSDLMVVQEHFAVRIP 154 Query: 111 EGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLV 170 + L L AA + A +T + L G + G +V + A++ + G V Sbjct: 155 DALPLDSAAPLLCAGITVYSPLRYYGLDKPGLHVGVVGLGGLG-HMAVKFAKAFGVKVTV 213 Query: 171 TAGSQKKLQMAEK-LGAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIGGSY-WEKNVNC 228 + S K + A LGA + + +A + G I+D + S+ ++ Sbjct: 214 VSTSPAKKEDAISGLGAHSFILSTDAEQMQAAVGTMDG-----IIDTVSASHPLPPLISL 268 Query: 229 LALDGRWVLYGLMGGGDINGPLFSKLLFKRGSLITSLLRSRDNKYKQMLVNAFTEQILPH 288 L G+ V+ G + P+F LL ++ + S + T++++ Sbjct: 269 LKSHGKLVMVGDP-PKPLELPVFPLLLGRKM-VAGSAIGGMKE----------TQEMIDF 316 Query: 289 FSTEGPQRLLPVLDRIYPVTEIQEAHKYMEANKNIGKIVLEL 330 + EG + + V+ P+ + A + + + + V+++ Sbjct: 317 AAKEGVRADVEVI----PMDYVNTAMQRVSKSDVKYRFVIDI 354 >1O89-A nrPDB Length = 345 Score = 117 bits (292), Expect = 8e-27, Method: Composition-based stats. Identities = 60/341 (17%), Positives = 121/341 (35%), Gaps = 27/341 (7%) Query: 1 MLAVHFDKPGGPENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNI 60 + A+ ++ G V+ + + EG+V + V S+LN D + G+ I Sbjct: 22 LQALLLEQQDGKTLASVQTLDESRLPEGDVTVDVHWSSLNYKDALAITGKGKIIRNFPMI 81 Query: 61 LGLEASGHVAELGPGCQGHWKIGDTA------MALLPGGGQAQYVTVPEGLLMPIPEGLT 114 G++ +G V + G + GG A+ V L+ +P+GL Sbjct: 82 PGIDFAGTVRTSED---PRFHAGQEVLLTGWGVGENHWGGLAEQARVKGDWLVAMPQGLD 138 Query: 115 LTQAAAIPEAWLTAFQ---LLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVT 171 +A I A TA L G +++ GVG+ A+ L G + Sbjct: 139 ARKAMIIGTAGFTAMLCVMALEDAGVRPQDGEIVVTGASGGVGSTAVALLHKLGYQVVAV 198 Query: 172 AGSQKKLQMAEKLGAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIGGSYWEKNVNCLAL 231 +G + + + LGA+ + S K +D +G K + + Sbjct: 199 SGRESTHEYLKSLGASRVLPRDEFAESRPLEKQVWAG----AIDTVGDKVLAKVLAQMNY 254 Query: 232 DGRWVLYGLMGGGDINGPLFSKLL-FKRGSLITSLLRSRDNKYKQMLVNAFTEQILPHFS 290 G GL GG + + +L R + S++ + + + + F Sbjct: 255 GGCVAACGLAGGFTLPTTVMPFILRNVRLQGVDSVMTPPERRAQA--WQRLVADLPESFY 312 Query: 291 TEGPQRLLPVLDRIYPVTEIQEAHKYMEANKNIGKIVLELP 331 T+ + + ++E + + N+ G+ ++++ Sbjct: 313 TQAAKEIS--------LSEAPNFAEAIINNQIQGRTLVKVN 345 >5FI5-A nrPDB Length = 357 Score = 117 bits (292), Expect = 1e-26, Method: Composition-based stats. Identities = 58/334 (17%), Positives = 113/334 (33%), Gaps = 53/334 (15%) Query: 26 GEGEVLLKVAASALNRADLMQRQGQYDPPPGASNILGLEASGHVAELGPGCQGHWKIGDT 85 GE +V LKV + D + ++ +LG E G V E+G Q +K+GD Sbjct: 41 GEHDVQLKVLYCGTCQYDREMSKNKFGF-TSYPYVLGHEIVGEVTEVGSKVQ-KFKVGDK 98 Query: 86 AMALL---------------------------PGGGQAQYVTVPEGLLMPIPEGLTLTQA 118 G + + E ++ PE L L Sbjct: 99 VGVASIIETCGKCEMCTNEVENYCPEAGSIDSNYGACSNIAVINENFVIRWPENLPLDSG 158 Query: 119 AAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGS-QKK 177 + A +TA+ + G + G + I A++ + GA V + S +KK Sbjct: 159 VPLLCAGITAYSPMKRYGLDKPGKRIGIAGLGGLG-HVALRFAKAFGAKVTVISSSLKKK 217 Query: 178 LQMAEKLGAAAGFNYKKEDFSEATLKFTKGAGVNLILDCI-GGSYWEKNVNCLALDGRWV 236 + EK GA + + + G I+D I G E + L G+ + Sbjct: 218 REAFEKFGADSFLVSSNPEEMQGAAGTLDG-----IIDTIPGNHSLEPLLALLKPLGKLI 272 Query: 237 LYGLMGGGDINGPLFSKLLFKRGSLITSLLRSRDNKYKQMLVNAFTEQILPHFSTEGPQR 296 + G ++ + + L G ++ + + ++M+ F+ E Sbjct: 273 ILGAP---EMPFEVPAPSLLMGGKVMAASTAGSMKEIQEMI----------EFAAEHNIV 319 Query: 297 LLPVLDRIYPVTEIQEAHKYMEANKNIGKIVLEL 330 + I + A + ++ + + V+++ Sbjct: 320 ADVEVISI---DYVNTAMERLDNSDVRYRFVIDI 350 >5VKT-A nrPDB Length = 362 Score = 116 bits (290), Expect = 2e-26, Method: Composition-based stats. Identities = 57/344 (16%), Positives = 113/344 (32%), Gaps = 63/344 (18%) Query: 26 GEGEVLLKVAASALNRADLMQRQGQYDPPPGASNILGLEASGHVAELGPGCQGHWKIGDT 85 G+ +V +KV + DL + ++ + G E G V ++G G +K GDT Sbjct: 33 GDADVTIKVLFCGICHTDLHVIKNEWGNA-MYPVVPGHEVVGVVTDVGHGVT-KFKAGDT 90 Query: 86 A-------------------------------------MALLPGGGQAQYVTVPEGLLMP 108 GG + + V + ++ Sbjct: 91 VGVGYFVDSCRTCESCSTGHENYCPDLVLTSNGVDHHHHGATTKGGFSDVLVVSQDFVVR 150 Query: 109 IPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIP 168 +PE L L AA + A +T + + + G ++ + A++ + G Sbjct: 151 VPESLPLDGAAPLLCAGVTVYSPMAQYALNEPGKHLGVVGLGGLG-HMAVKFAKAFGMTV 209 Query: 169 LVTAGSQKKLQMAE-KLGAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIG-GSYWEKNV 226 V + S K A +LGA A +A G I+D + G + Sbjct: 210 TVISSSPGKRDEALGRLGADAFLVSHDAAQMKAAAATLDG-----IIDTVSAGHQIVPLL 264 Query: 227 NCLALDGRWVLYGLMGGGDINGPLFSKLLFKRGSLITSLLRSRDNKYKQMLVNAFTEQIL 286 L G+ V+ G + P ++ ++ + + + S + + +L Sbjct: 265 ALLKPMGQMVVVGAPS-TPLELPAYA-IITGGKRVAGNGVGSVAD----------CQAML 312 Query: 287 PHFSTEGPQRLLPVLDRIYPVTEIQEAHKYMEANKNIGKIVLEL 330 G + V+ Y + A + +E N + V+++ Sbjct: 313 DFAGEHGVTADIEVVQMDY----VNTAIERLEKNDVRYRFVIDV 352 >6C49-A nrPDB Length = 350 Score = 113 bits (283), Expect = 1e-25, Method: Composition-based stats. Identities = 60/346 (17%), Positives = 118/346 (34%), Gaps = 53/346 (15%) Query: 13 ENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNILGLEASGHVAEL 72 E L + +V +KV L +D+ ++ + G E G + L Sbjct: 24 EKLVPYKFDAGELQPHQVEVKVEYCGLCHSDISVLNNEWHS-TVYPVVAGHEIIGRIVAL 82 Query: 73 GPGCQG--------------HWKIGDTAMA--------------LLPGGGQAQYVTVPEG 104 G +G + D + + GG A V Sbjct: 83 GSEAKGLQIGQRVGIGWTAESCQACDECIGGQQVLCTGENIATIVGHAGGFADKVRAGWQ 142 Query: 105 LLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMA 164 +P+PE L A + +T F L L +QA +V + G+G AI+L + Sbjct: 143 WAIPLPEDLDPESAGPLLCGGITVFDPL-LKHKIQATHHVGVIGIG-GLGHIAIKLLKAW 200 Query: 165 GAIPLVTAGSQKKLQMAEKLGAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIGGS-YWE 223 G + + K + + +GA N + + +A +L+L + + W Sbjct: 201 GCEITAFSSNPDKTEELKAMGADHVVNSRDTEAVKAQK-----GKFDLLLSTVNVTLNWR 255 Query: 224 KNVNCLALDGRWVLYGLMGGGDINGPLFSKLLFKRGSLITSLLRSRDNKYKQMLVNAFTE 283 ++ LA +G GL + L+ S+ S S Sbjct: 256 AFISTLAPNGSLHFLGL--TLEPVPVSVGSLIDGAKSVTGSPTGS-------------PA 300 Query: 284 QILPHFSTEGPQRLLPVLDRIYPVTEIQEAHKYMEANKNIGKIVLE 329 + +++ P + ++P++++ EA + + + + +IVL+ Sbjct: 301 ALRQLLKFAARKKIAPQI-ELFPMSQLNEAIERLHSGQARYRIVLK 345 >5GXF-A nrPDB Length = 330 Score = 112 bits (281), Expect = 2e-25, Method: Composition-based stats. Identities = 59/329 (17%), Positives = 112/329 (34%), Gaps = 30/329 (9%) Query: 13 ENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNILGLEASGHVAEL 72 + L + ++ GEV + V S +N D + ++ G++ +G V Sbjct: 21 KQLSLTDLPV-----GEVTVAVEYSTVNYKDGLCIGPGGGLVRKYPHVPGIDFAGTVE-- 73 Query: 73 GPGCQGHWKIGDTAM------ALLPGGGQAQYVTVPEGLLMPIPEGLTLTQAAAIPEAWL 126 +K GD + GG +Q V L+P+PEGL QA A+ A Sbjct: 74 -NSSDERYKPGDKVVLTGWRVGEAHWGGYSQKANVRADWLVPLPEGLDTRQAMAVGTAGF 132 Query: 127 TAFQLLH--LVGNVQAGD-YVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQMAEK 183 TA + + G VL+ GVG+ A + G G + Sbjct: 133 TAMLAVMALEDHGLTPGHGPVLVTGAAGGVGSVATAILAHLGYEVAAVTGRPETADYLTS 192 Query: 184 LGAAAGFNYKK-EDFSEATLKFTKGAGVNLILDCIGGSYWEKNVNCLALDGRWVLYGLMG 242 LGA + + + L+ AG +D +GG+ + + + GL G Sbjct: 193 LGATQIVARDEINETVKRPLESEIWAGC---VDAVGGAMLARVLGQMKYGASVAAVGLAG 249 Query: 243 GGDINGPLFSKLLFKRGSLITSLLRSRDNKYKQMLVNAFTEQILPHFSTEGPQRLLPVLD 302 G + + LL + L + + A+ + + P Sbjct: 250 GAGLPATVIPFLL----RGVNLLGIDSVMQPYANRLRAWERIARDLPMDKLEAMIRPAT- 304 Query: 303 RIYPVTEIQEAHKYMEANKNIGKIVLELP 331 ++++ + + G++V+++ Sbjct: 305 ----LSDLPGLGADILKGQVQGRVVVDVN 329 >3M6I-A nrPDB Length = 363 Score = 105 bits (261), Expect = 4e-23, Method: Composition-based stats. Identities = 65/329 (19%), Positives = 119/329 (36%), Gaps = 57/329 (17%) Query: 24 SPGEGEVLLKVAASALNRADLM-QRQGQYDP-PPGASNILGLEASGHVAELGPGCQGHWK 81 EGEV + V ++ + +D+ + G P ++LG E++G V + P + K Sbjct: 37 ELKEGEVTVAVRSTGICGSDVHFWKHGCIGPMIVECDHVLGHESAGEVIAVHPSVKS-IK 95 Query: 82 IGDTA--------MALLP--------------------GGGQAQYVTVPEGLLMPIPEGL 113 +GD A P G +YV P I + Sbjct: 96 VGDRVAIEPQVICNACEPCLTGRYNGCERVDFLSTPPVPGLLRRYVNHPAVWCHKIG-NM 154 Query: 114 TLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIP-LVTA 172 + A + E A L G V+ GD VLI G +G + + AGA P ++T Sbjct: 155 SYENGAML-EPLSVALAGLQRAG-VRLGDPVLIC-GAGPIGLITMLCAKAAGACPLVITD 211 Query: 173 GSQKKLQMAEKLGAAAGFNYK-----KEDFSEATLKFTKGAGVNLILDCIG-GSYWEKNV 226 + +L+ A+++ +K E+ ++ ++ G + L+C G S + Sbjct: 212 IDEGRLKFAKEI-CPEVVTHKVERLSAEESAKKIVESFGGIEPAVALECTGVESSIAAAI 270 Query: 227 NCLALDGRWVLYGLMGGGDINGPLFSKLLFKRGSLITSLLRSRDNKYKQMLVNAFTEQIL 286 + G+ + G +G +I P F R S+ R+ + T Sbjct: 271 WAVKFGGKVFVIG-VGKNEIQIP------FMRASV-------REVDLQFQYRYCNTWPRA 316 Query: 287 PHFSTEGPQRLLPVLDRIYPVTEIQEAHK 315 G L ++ +P+ + +A + Sbjct: 317 IRLVENGLVDLTRLVTHRFPLEDALKAFE 345 >5H82-A nrPDB Length = 389 Score = 102 bits (253), Expect = 3e-22, Method: Composition-based stats. Identities = 59/356 (16%), Positives = 112/356 (31%), Gaps = 74/356 (20%) Query: 26 GEGEVLLKVAASALNRADLMQRQGQYDPPPGASNILGLEASGHVAELGPGCQGHWKIGD- 84 GE +V KV L D++ + Y + G E G V E+G + +K+GD Sbjct: 52 GEHDVQFKVLYCGLCDWDVITTKNTYGT-TKYPFVPGHEIMGIVTEIGNKVK-KFKVGDK 109 Query: 85 ----------------------------------------TAMALLPG-------GGQAQ 97 T + G GG + Sbjct: 110 VGVGNFIGSCGKCERCNEGLEPYCPKVIYTDGTAFSDENNTVYGDVSGDGEDRIYGGYSN 169 Query: 98 YVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAA 157 + E ++ PE L L I + + + G + G + + G +G A Sbjct: 170 IMVANEYVVFRWPENLPLAAGVPILCGGIVPYSPMRHFGLDKPGLSIGVV-GFGRIGKLA 228 Query: 158 IQLTRMAGAIP-LVTAGSQKKLQMAEKLGAAAGFNYKKEDFSEATLKFTKGAGVNLILDC 216 ++ + GA +++ KK + EK G K+ + +A G I DC Sbjct: 229 VKFAKAFGANVTVISTSISKKQEAIEKYGVDRFLISKEPEEMKAAESTLDG-----IFDC 283 Query: 217 I-GGSYWEKNVNCLALDGRWVLYGLMGGGDINGPLFSKLLFKRGSLITSLLRSRDNKYKQ 275 + +N L +G +V+ G+ + S LL R + S+ + + Sbjct: 284 VPSVHPLHPLLNLLKFEGTFVMLGVA--VEAYELPVSPLLMGRRKFVGSISGTMKETQEM 341 Query: 276 MLVNAFTEQILPHFSTEGPQRLLPVLDRIYPVTEIQEAHKYMEANKNIGKIVLELP 331 + A + + P+ + A + + + V+++ Sbjct: 342 LDFAAKHNIVSDI--------------ELIPMDYVNTALERIAKGNHKDAFVIDIE 383 >2CF5-A nrPDB Length = 357 Score = 94.4 bits (233), Expect = 7e-20, Method: Composition-based stats. Identities = 63/344 (18%), Positives = 120/344 (34%), Gaps = 63/344 (18%) Query: 26 GEGEVLLKVAASALNRADLMQRQGQYDPPPGASNILGLEASGHVAELGPGCQGHWKIGD- 84 G +V +++ + DL Q + + G E G V E+G + +GD Sbjct: 33 GPEDVNIRIICCGICHTDLHQTKNDLGM-SNYPMVPGHEVVGEVVEVGSDVS-KFTVGDI 90 Query: 85 ----------------------------------TAMALLPGGGQAQYVTVPEGLLMPIP 110 GG A+ V + ++ IP Sbjct: 91 VGVGCLVGCCGGCSPCERDLEQYCPKKIWSYNDVYINGQPTQGGFAKATVVHQKFVVKIP 150 Query: 111 EGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLV 170 EG+ + QAA + A +T + L G ++ GL GVG +++ + G V Sbjct: 151 EGMAVEQAAPLLCAGVTVYSPLSHFG-LKQPGLRGGILGLGGVGHMGVKIAKAMGHHVTV 209 Query: 171 TAGSQKKLQMAEK-LGAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIG-GSYWEKNVNC 228 + S KK + A + LGA + ++ ++D + E ++ Sbjct: 210 ISSSNKKREEALQDLGADDYVIGS-----DQAKMSELADSLDYVIDTVPVHHALEPYLSL 264 Query: 229 LALDGRWVLYGLM-GGGDINGPLFSKLLFKRGSLITSLLRSRDNKYKQMLVNAFTEQILP 287 L LDG+ +L G++ PL L+ R + S + S K + ++ E+ L Sbjct: 265 LKLDGKLILMGVINNPLQFLTPL---LMLGRKVITGSFIGS--MKETEEMLEFCKEKGLS 319 Query: 288 HFSTEGPQRLLPVLDRIYPVTEIQEAHKYMEANKNIGKIVLELP 331 + + + + A + +E N + V+++ Sbjct: 320 S------------IIEVVKMDYVNTAFERLEKNDVRYRFVVDVE 351 >6DKH-A nrPDB Length = 346 Score = 92.1 bits (227), Expect = 3e-19, Method: Composition-based stats. Identities = 68/333 (20%), Positives = 110/333 (33%), Gaps = 53/333 (15%) Query: 31 LLKVAASALNRADLMQRQ-GQYDP-PPGASNILGLEASGHV-----AELGPGCQ------ 77 L+++ + +DL Q G+ A +LG E G V +EL G Sbjct: 34 LVQITRGGICGSDLHYYQEGKVGNFMIKAPMVLGHEVIGKVIHSDSSELHEGQTVAINPS 93 Query: 78 ---GHWKIGDTAMALLP---------------GGGQAQYVTVPEGLLMPIPEGLTLTQAA 119 GH K GG +Y V +P P + Sbjct: 94 KPCGHCKYCIEHNENQCTDMRFFGSAMYFPHVDGGFTRYKMVETSQCVPYPAKAD-EKVM 152 Query: 120 AIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGA-IPLVTAGSQKKL 178 A E A H G +Q G V I +G+ +G + + GA + S + L Sbjct: 153 AFAEPLAVAIHAAHQAGELQ-GKRVFI-SGVGPIGCLIVSAVKTLGAAEIVCADVSPRSL 210 Query: 179 QMAEKLGAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIG-GSYWEKNVNCLALDGRWVL 237 + +++GA N + +D K KG ++ + G S + G V Sbjct: 211 SLGKEMGADVLVNPQNDDM--DHWKAEKGY-FDVSFEVSGHPSSVNTCLEVTRARGVMVQ 267 Query: 238 YGLMGGGDINGPLFSKLLFKRGSLITSLLRSRDNKYKQMLVNAFTEQILPHFSTEGPQRL 297 G+ GG + L+ K SL S + + + G Sbjct: 268 VGM--GGAMAEFPMMTLIGKEISLRGSFRFTSEFN------------TAVSWLANGVINP 313 Query: 298 LPVLDRIYPVTEIQEAHKYMEANKNIGKIVLEL 330 LP+L YP T+++EA ++ K+ L Sbjct: 314 LPLLSAEYPFTDLEEALRFAGDKTQAAKVQLVF 346 >5H83-A nrPDB Length = 360 Score = 91.7 bits (226), Expect = 4e-19, Method: Composition-based stats. Identities = 59/338 (17%), Positives = 109/338 (32%), Gaps = 57/338 (16%) Query: 26 GEGEVLLKVAASALNRADLMQRQGQYDPPPGASNILGLEASGHVAELGPGCQGHWKIGDT 85 GE +V KV DL ++ ++G E G V E+G Q +K+GD Sbjct: 38 GENDVQFKVLYCGTCNYDLEMSTNKFGM-TKYPFVIGHEIVGVVTEIGSKVQ-KFKVGDK 95 Query: 86 A----------------MALLPG---------------GGQAQYVTVPEGLLMPIPEGLT 114 + GG + V E + PE L Sbjct: 96 VGVGGFVGACEKCEMCVNGVENNCSKVESTDGHFGNNFGGCCNIMVVNEKYAVVWPENLP 155 Query: 115 LTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGS 174 L + A +T + L G + G + I G+G AI+ + GA + + S Sbjct: 156 LHSGVPLLCAGITTYSPLRRYGLDKPGLNIGIAGLG-GLGHLAIRFAKAFGAKVTLISSS 214 Query: 175 -QKKLQMAEKLGAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIGGSYWEKNVNCLALDG 233 +KK + EK G + + + G +I + L G Sbjct: 215 VKKKREALEKFGVDSFLLNSNPEEMQGAYGTLDG----IIDTMPVAHSIVPFLALLKPLG 270 Query: 234 RWVLYGLM-GGGDINGPLFSKLLFKRGSLITSLLRSRDNKYKQMLVNAFTEQILPHFSTE 292 + ++ G+ ++ P L G LI + ++M+ A I+ Sbjct: 271 KLIILGVPEEPFEVPAPA----LLMGGKLIAGSAAGSMKETQEMIDFAAKHNIVADVE-- 324 Query: 293 GPQRLLPVLDRIYPVTEIQEAHKYMEANKNIGKIVLEL 330 + P+ + A + ++ + + V+++ Sbjct: 325 -----------VIPIDYLNTAMERIKNSDVKYRFVIDV 351 >2VWH-A nrPDB Length = 357 Score = 77.8 bits (190), Expect = 7e-15, Method: Composition-based stats. Identities = 57/363 (15%), Positives = 118/363 (32%), Gaps = 67/363 (18%) Query: 1 MLAVHFDKPGGPENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYD--PPPGAS 58 M A+ + G + V E +P P GE L++ ++ D G + P Sbjct: 1 MKAIAVKR--GEDRPVVIEKPRPEPESGEALVRTLRVGVDGTDHEVIAGGHGGFPEGEDH 58 Query: 59 NILGLEASGHVAELGPGCQGHWKIGDTAMALL--------------------PGGGQ--- 95 +LG EA G V + P + GD + + P G Sbjct: 59 LVLGHEAVGVVVD--PNDTE-LEEGDIVVPTVRRPPASGTNEYFERDQPDMAPDGMYFER 115 Query: 96 ---------AQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAG----D 142 +++ T PE L+ IP + + + E + L ++ Sbjct: 116 GIVGAHGYMSEFFTSPEKYLVRIPR--SQAELGFLIEPISITEKALEHAYASRSAFDWDP 173 Query: 143 YVLIHAGLSGVGTAAIQLTRM--AGAIPLVTAGSQKK----LQMAEKLGAAAGFNYKKED 196 G +G + + ++ G L G + + + + E+L A ++ Sbjct: 174 SSAFVLGNGSLGLLTLAMLKVDDKGYENLYCLGRRDRPDPTIDIIEELDATYV--DSRQT 231 Query: 197 FSEATLKFTKGAGVNLILDCIG-GSYWEKNVNCLALDGRWVLYGLMG--GGDINGPLFSK 253 E ++ I + G + ++V LA +G L G+ +++ F + Sbjct: 232 PVEDVPDVY--EQMDFIYEATGFPKHAIQSVQALAPNGVGALLGVPSDWAFEVDAGAFHR 289 Query: 254 LLFKRGSLITSLLRSRDNKYKQMLVNAFTEQILPHFSTEGPQRLLPVLDRIYPVTEIQEA 313 + + + S ++ V F+ L ++ ++P++E + A Sbjct: 290 EMVLHNKALVGSVNSHVEHFEAATVT---------FTKLPKWFLEDLVTGVHPLSEFEAA 340 Query: 314 HKY 316 Sbjct: 341 FDD 343 >2DPH-A nrPDB Length = 398 Score = 77.8 bits (190), Expect = 7e-15, Method: Composition-based stats. Identities = 73/411 (17%), Positives = 132/411 (32%), Gaps = 105/411 (25%) Query: 2 LAVHFDKPGGPENLYVKEVAKPSPG------EGEVLLKVAASALNRADLMQRQGQYDPPP 55 +V + G +L V+ V P E V+LKV ++ + +D +G++ P Sbjct: 4 KSVVYH---GTRDLRVETVPYPKLEHNNRKLEHAVILKVVSTNICGSDQHIYRGRFIVPK 60 Query: 56 GASNILGLEASGHVAELGPGCQ----------------GHWKIGDTAMALLPG------- 92 G ++LG E +G V E G + G + A + + Sbjct: 61 G--HVLGHEITGEVVEKGSDVELMDIGDLVSVPFNVACGRCRNCKEARSDVCENNLVNPD 118 Query: 93 --------------GGQAQYVTVP-----------EGLLMPIPEGLTLTQAAAIPEAWLT 127 GGQA+YV VP + M + LTL I + T Sbjct: 119 ADLGAFGFDLKGWSGGQAEYVLVPYADYMLLKFGDKEQAMEKIKDLTL-----ISDILPT 173 Query: 128 AFQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAI-PLVTAGSQKKLQMAEKLGA 186 F + V+ G +V I AG VG A R+ GA +V + ++L++ G Sbjct: 174 GFHGC-VSAGVKPGSHVYI-AGAGPVGRCAAAGARLLGAACVIVGDQNPERLKLLSDAGF 231 Query: 187 AAGFNYKKEDFSEATLKFTKGAGVNLILDCIG---------------GSYWEKNVNCLAL 231 + + V+ +D +G + + Sbjct: 232 ETIDLRNSAPLRDQIDQILGKPEVDCGVDAVGFEAHGLGDEANTETPNGALNSLFDVVRA 291 Query: 232 DGRWVLYGLMGGGDINGPL------------FSKLLFKRGSLITSLLRSRDNKYKQMLVN 279 G + G+ G D P+ F K+ K ++T + Y + L Sbjct: 292 GGAIGIPGIYVGSD-PDPVNKDAGSGRLHLDFGKMWTKSIRIMTGMAPV--TNYNRHLTE 348 Query: 280 AFTEQILPHFSTEGPQRLLPVLDRIYPVTEIQEAHKYMEANKNIGKIVLEL 330 A +P+ S + + + + + + + K V++ Sbjct: 349 AILWDQMPYLS-------KVMNIEVITLDQAPDGYAKFDKGSPA-KFVIDP 391 >4JLW-A nrPDB Length = 399 Score = 76.6 bits (187), Expect = 1e-14, Method: Composition-based stats. Identities = 53/258 (20%), Positives = 89/258 (34%), Gaps = 54/258 (20%) Query: 11 GPENLYVKEVAKPSPGEGE-------VLLKVAASALNRADLMQRQGQYDPPPGASNILGL 63 GP + V+ + P + + V+L+V ++ + +D +G+ P G +LG Sbjct: 11 GPGKVEVQNIPYPKMQDPQGRQIDHGVILRVVSTNICGSDQHMVRGRTTAPEGL--VLGH 68 Query: 64 EASGHVAELGPGCQ----------------GHWKIGDT--------AMALLPGGGQ---- 95 E +G V E+G G + GH + GG Sbjct: 69 EITGEVVEIGRGVETMKIGDLVSVPFNVACGHCRTCKEQHTGVCLTVNPARAGGAYGYVD 128 Query: 96 --------AQYVTVP--EGLLMPIPEGLTLTQ----AAAIPEAWLTAFQLLHLVGNVQAG 141 A+YV VP + L+ +P + + + T + + V G Sbjct: 129 MGGWVGGQAEYVLVPYADFNLLKLPNREAAMEKIRDLTCLSDILPTGYHGA-VTAGVGPG 187 Query: 142 DYVLIHAGLSGVGTAAIQLTRMAGAIPLVT-AGSQKKLQMAEKLGAAAGFNYKKEDFSEA 200 V I AG VG AA R+ GA ++ + +L A+K G K E Sbjct: 188 STVYI-AGAGPVGLAAAASARLLGAAVVIVGDVNPTRLAHAKKQGFEIADLSKDTPLHEQ 246 Query: 201 TLKFTKGAGVNLILDCIG 218 V+ +D +G Sbjct: 247 IAALLGEPEVDCAVDAVG 264 >1KOL-A nrPDB Length = 398 Score = 67.0 bits (162), Expect = 1e-11, Method: Composition-based stats. Identities = 67/399 (16%), Positives = 120/399 (30%), Gaps = 77/399 (19%) Query: 2 LAVHFDKPGGPENLYVKEVAKPSPG----EGEVLLKVAASALNRADLMQRQGQYDPPPGA 57 V + G E + P E V+LKV ++ + +D +G+ G Sbjct: 4 RGVVYLGSGKVEVQKIDYPKMQDPRGKKIEHGVILKVVSTNICGSDQHMVRGRTTAQVGL 63 Query: 58 SNILGLEASGHVAELGPGCQGHWKIGD-------------------------TAMALLPG 92 +LG E +G V E G + + +IGD T G Sbjct: 64 --VLGHEITGEVIEKGRDVE-NLQIGDLVSVPFNVACGRCRSCKEMHTGVCLTVNPARAG 120 Query: 93 GGQ------------AQYVTVP--EGLLMPIPEGLTLTQ----AAAIPEAWLTAFQLLHL 134 G A+YV VP + L+ +P+ + + + T + + Sbjct: 121 GAYGYVDMGDWTGGQAEYVLVPYADFNLLKLPDRDKAMEKIRDLTCLSDILPTGYHGA-V 179 Query: 135 VGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVT-AGSQKKLQMAEKLGAAAGFNYK 193 V G V + AG VG AA R+ GA ++ + +L A+ G Sbjct: 180 TAGVGPGSTVYV-AGAGPVGLAAAASARLLGAAVVIVGDLNPARLAHAKAQGFEIADLSL 238 Query: 194 KEDFSEATLKFTKGAGVNLILDCIG----------------GSYWEKNVNCLALDGRWVL 237 E V+ +D +G + + + G+ Sbjct: 239 DTPLHEQIAALLGEPEVDCAVDAVGFEARGHGHEGAKHEAPATVLNSLMQVTRVAGKI-- 296 Query: 238 YGLMGGGDINGPLFSKLLFKRGSLITSL----LRSRDNKYKQMLVNAFTEQILPHFSTEG 293 G+ G P K GSL +S Q V + ++ + Sbjct: 297 -GIPGLYVTEDPGAVDAAAKIGSLSIRFGLGWAKSHSFHTGQTPVMKYNRALMQAIMWDR 355 Query: 294 PQRLLPVLDRIYPVTEIQEAHKYMEANKNIGKIVLELPQ 332 V ++ + + + +A K V++ + Sbjct: 356 INIAEVVGVQVISLDDAPRGYGEFDAG-VPKKFVIDPHK 393 >2CDC-A nrPDB Length = 366 Score = 58.5 bits (140), Expect = 4e-09, Method: Composition-based stats. Identities = 59/380 (15%), Positives = 118/380 (31%), Gaps = 65/380 (17%) Query: 1 MLAVHFDKPGGPENLYVKEVAKPSP-GEGEVLLKVAASALNRADLMQRQGQYD----PPP 55 M A+ P + VK+V + G++ ++ + + AD G+ P Sbjct: 1 MKAIIVKPPN--AGVQVKDVDEKKLDSYGKIKIRTIYNGICGADREIVNGKLTLSTLPKG 58 Query: 56 GASNILGLEASGHVAELGPGCQGHWKIGDTAMALLPGG-GQAQYVTV------------- 101 +LG EA G V E G + GD M + G G + V Sbjct: 59 KDFLVLGHEAIGVVEESYHG----FSQGDLVMPVNRRGCGICRNCLVGRPDFCETGEFGE 114 Query: 102 ----------------PEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYV- 144 L+ IP+ + A P A + + + + VQ V Sbjct: 115 AGIHKMDGFMREWWYDDPKYLVKIPKSIEDIGILAQPLADI--EKSIEEILEVQKRVPVW 172 Query: 145 -----------LIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQMAEKLGAAAGFNYK 193 ++ G +G L R G + + + Y Sbjct: 173 TCDDGTLNCRKVLVVGTGPIGVLFTLLFRTYGLEVWMANRREPTEVEQTVIEETKTNYYN 232 Query: 194 KEDFSEATLKFTKGAGVNLILDCIGGSY--WEKNVNCLALDGRWVLYGLMGGGDINGP-- 249 + + ++I+D G + L +G L+G G + Sbjct: 233 SSNGYDKLKDSVG--KFDVIIDATGADVNILGNVIPLLGRNGVLGLFGFSTSGSVPLDYK 290 Query: 250 LFSKLLFKRGSLITSLLRSRDNKYKQMLVNAFTEQILPHFSTEGPQRLLPVLDRIYPVTE 309 +++ ++I L+ + ++Q +V+ + + L + + L+ I E Sbjct: 291 TLQEIVHTNKTIIG-LVNGQKPHFQQAVVHLASWKTLY---PKAAKMLITKTVSINDEKE 346 Query: 310 IQEAHKYMEANKNIGKIVLE 329 + + + E + +I+ E Sbjct: 347 LLKVLREKEHGEIKIRILWE 366 >3WID-A nrPDB Length = 369 Score = 50.5 bits (119), Expect = 1e-06, Method: Composition-based stats. Identities = 51/314 (16%), Positives = 98/314 (31%), Gaps = 65/314 (20%) Query: 3 AVHFDKPGGPENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQ----YDPPPGAS 58 A+ D P G + ++ P P + E LK + D + G Y+P Sbjct: 6 AIVTDAPKG--GVKYTKIDMPEPEKYEAKLKPVYIGICGTDRGEVAGALSFTYNPEGENF 63 Query: 59 NILGLEASGHVAELGPGCQGHWKIGDTAMALL-PGG------------------------ 93 +LG EA V ++ + K GD + L+ G Sbjct: 64 LVLGHEALLQVLDVSDN--NYIKRGDFVVPLVRRPGKCVNCRIGRQDNCSIGDPDKHEAG 121 Query: 94 -----GQAQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHA 148 G + V + + L + A + E + V +V + + + Sbjct: 122 ITGLHGFMRDVIYDDIQNLVKVNDPDLGKIAVLTEPLKNVMKA-FEVFDVVSKRSIFQND 180 Query: 149 GLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQMAEKLGAAAGFNYKKEDFSEATLKFTKGA 208 + +G + + + A G + G + D +E +K Sbjct: 181 DSTFIGKKMVVIGSGSEAFLYSFVG--------KDRGFDVTMVNRH-DETENKMKMMDDF 231 Query: 209 GV-------------NLILDCIGGSYWE-KNVNCLALDGRWVLYGL---MGGGDINGPLF 251 GV +L++D G K V + +G +L+G G +NG Sbjct: 232 GVGFSNYLKDMPDKIDLLVDTSGDPSTIFKFVKKVNNNGVVILFGFNGKAPGYPVNGEDI 291 Query: 252 SKLLFKRGSLITSL 265 ++ + ++ S+ Sbjct: 292 DYIVERNITIAGSV 305 >3D3W-A nrPDB Length = 244 Score = 39.3 bits (90), Expect = 0.002, Method: Composition-based stats. Identities = 14/93 (15%), Positives = 30/93 (32%), Gaps = 1/93 (1%) Query: 140 AGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQ-MAEKLGAAAGFNYKKEDFS 198 AG VL+ G+G +Q GA + + +Q L + + D+ Sbjct: 6 AGRRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQADLDSLVRECPGIEPVCVDLGDWE 65 Query: 199 EATLKFTKGAGVNLILDCIGGSYWEKNVNCLAL 231 V+L+++ + + + Sbjct: 66 ATERALGSVGPVDLLVNNAAVALLQPFLEVTKE 98 >4INE-A nrPDB Length = 454 Score = 39.3 bits (90), Expect = 0.002, Method: Composition-based stats. Identities = 31/168 (18%), Positives = 58/168 (34%), Gaps = 11/168 (6%) Query: 130 QLLHLVGNVQAGDYVL-IHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQMAEKLGAAA 188 +++ G+ + G +L I G+ G A Q+ G S L +A + Sbjct: 231 KIIKRFGDFKPGQTMLDIGVGIGGG---ARQVADEFGVHVHGIDLSSNMLAIALERLHEE 287 Query: 189 GFNYKKEDFSEATLKFTKGAGVNLIL--DCI-----GGSYWEKNVNCLALDGRWVLYGLM 241 + K ++A + + + + DCI + + L G+ ++ Sbjct: 288 KDSRVKYSITDALVYQFEDNSFDYVFSRDCIQHIPDTEKLFSRIYKALKPGGKVLITMYG 347 Query: 242 GGGDINGPLFSKLLFKRGSLITSLLRSRDNKYKQMLVNAFTEQILPHF 289 G F + +R + +L D K VN TE + P F Sbjct: 348 KGYGEQSDKFKTYVAQRAYFLKNLKEIADIANKTGFVNVQTENMTPRF 395 >3RSH-A nrPDB Length = 251 Score = 38.1 bits (87), Expect = 0.005, Method: Composition-based stats. Identities = 21/85 (24%), Positives = 32/85 (37%), Gaps = 6/85 (7%) Query: 140 AGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQMAEKL----GAAAGFNYKKE 195 G L+ G+G A +L GA + TA S+ Q G N Sbjct: 11 EGKVALVTGASRGIGKAIAELLAERGAKVIGTATSESGAQAISDYLGDNGKGMALNVTNP 70 Query: 196 DFSEATLKFTKGA--GVNLILDCIG 218 + EA LK GV+++++ G Sbjct: 71 ESIEAVLKAITDEFGGVDILVNNAG 95 >5TQV-A nrPDB Length = 233 Score = 38.1 bits (87), Expect = 0.006, Method: Composition-based stats. Identities = 17/79 (21%), Positives = 26/79 (32%), Gaps = 3/79 (3%) Query: 142 DYVLIHAGLSGVG-TAAIQLTRMAGAIPLVTAGSQKKLQMAEKLGAA-AGFNYKKEDFSE 199 VLI G+G Q R G + TA L LGA + + + Sbjct: 10 KTVLIVGASRGLGREFVRQYQR-DGWNVIATARDDASLAALRALGAHAHALDITQPEQIA 68 Query: 200 ATLKFTKGAGVNLILDCIG 218 A G +++ + G Sbjct: 69 ALGWKLDGERLDVAVVVSG 87 >4X3Q-A nrPDB Length = 355 Score = 38.1 bits (87), Expect = 0.006, Method: Composition-based stats. Identities = 25/150 (16%), Positives = 47/150 (31%), Gaps = 12/150 (8%) Query: 146 IHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQMAEKLGAAAGFNYKKEDFSEATLKFT 205 + G A+ L R ++ + L++A K A AG + + + Sbjct: 174 VLDVGGGDAVNAVALARAHPSLRVTVLDRPGALEVARKTIAEAGLEERVRTHAADIFTDS 233 Query: 206 KGAGVNLILDCIGGSYWE---------KNVNCLALDGRWVLYGLMGGGDINGPL---FSK 253 AG + +L W K + + GR +++ D GPL Sbjct: 234 YPAGHDCVLFAHQLVIWSPEQNLTLLRKAYDAVEPGGRVLVFNAFTDDDRTGPLYAALDN 293 Query: 254 LLFKRGSLITSLLRSRDNKYKQMLVNAFTE 283 + F S + + + FT+ Sbjct: 294 VYFTTLPFRHSTIHRWADCESWLREAGFTD 323 >3PWS-A nrPDB Length = 366 Score = 36.2 bits (82), Expect = 0.019, Method: Composition-based stats. Identities = 20/97 (20%), Positives = 31/97 (31%), Gaps = 6/97 (6%) Query: 141 GDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQMAEKLGAAAGFNYKKEDFSEA 200 G V + VG Q+ +M L + +A A +K +D + Sbjct: 2 GYTVAVVGATGAVG---AQMIKMLEESTLPIDKIRY---LASARSAGKSLKFKDQDITIE 55 Query: 201 TLKFTKGAGVNLILDCIGGSYWEKNVNCLALDGRWVL 237 T GV++ L G S K G V+ Sbjct: 56 ETTETAFEGVDIALFSAGSSTSAKYAPYAVKAGVVVV 92 >3F9I-A nrPDB Length = 249 Score = 36.2 bits (82), Expect = 0.021, Method: Composition-based stats. Identities = 17/55 (30%), Positives = 28/55 (50%), Gaps = 3/55 (5%) Query: 141 GDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQMAEKLGAAAGFNYKKE 195 G LI SG+G+A +L G+ +++ +++KL + LG A NY E Sbjct: 14 GKTSLITGASSGIGSAIARLLHKLGSKVIISGSNEEKL---KSLGNALKDNYTIE 65 >4ER3-A nrPDB Length = 352 Score = 35.8 bits (81), Expect = 0.029, Method: Composition-based stats. Identities = 34/233 (14%), Positives = 74/233 (31%), Gaps = 27/233 (11%) Query: 110 PEGLTLTQAAAIPEAWLTAFQLL-HLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIP 168 PE L + + T+F L+ ++ ++ D L SGVG +Q+ Sbjct: 123 PEKLNNYEPFSPEVYGETSFDLVAQMIDEIKMTDDDLFVDLGSGVGQVVLQVAAATNCKH 182 Query: 169 ------------LVTAGSQKKLQMAEKLGAAAG-FNYKKEDFS-EATLKFTKGAGVNLIL 214 ++ + + G + ++ DF E + V + Sbjct: 183 HYGVEKADIPAKYAETMDREFRKWMKWYGKKHAEYTLERGDFLSEEWRERIANTSVIFVN 242 Query: 215 DCIGGSYWEKNVN----CLALDGRWVLYGLMGGGDINGPLFSKLLFKRGSLITSLLRSRD 270 + G + + + GR V PL ++ + S I +++R + Sbjct: 243 NFAFGPEVDHQLKERFANMKEGGRIV------SSKPFAPLNFRINSRNLSDIGTIMRVVE 296 Query: 271 NKYKQMLVNAFTEQILPHFSTEGPQRLLPVLDRIY--PVTEIQEAHKYMEANK 321 + V+ + + + T L + + E QEA + + + Sbjct: 297 LSPLKGSVSWTGKPVSYYLHTIDRTILENYFSSLKNPKLREEQEAARRRQQRE 349 >3UWP-A nrPDB Length = 438 Score = 35.8 bits (81), Expect = 0.029, Method: Composition-based stats. Identities = 34/233 (14%), Positives = 74/233 (31%), Gaps = 27/233 (11%) Query: 110 PEGLTLTQAAAIPEAWLTAFQLL-HLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIP 168 PE L + + T+F L+ ++ ++ D L SGVG +Q+ Sbjct: 140 PEKLNNYEPFSPEVYGETSFDLVAQMIDEIKMTDDDLFVDLGSGVGQVVLQVAAATNCKH 199 Query: 169 ------------LVTAGSQKKLQMAEKLGAAAG-FNYKKEDFS-EATLKFTKGAGVNLIL 214 ++ + + G + ++ DF E + V + Sbjct: 200 HYGVEKADIPAKYAETMDREFRKWMKWYGKKHAEYTLERGDFLSEEWRERIANTSVIFVN 259 Query: 215 DCIGGSYWEKNVN----CLALDGRWVLYGLMGGGDINGPLFSKLLFKRGSLITSLLRSRD 270 + G + + + GR V PL ++ + S I +++R + Sbjct: 260 NFAFGPEVDHQLKERFANMKEGGRIV------SSKPFAPLNFRINSRNLSDIGTIMRVVE 313 Query: 271 NKYKQMLVNAFTEQILPHFSTEGPQRLLPVLDRIY--PVTEIQEAHKYMEANK 321 + V+ + + + T L + + E QEA + + + Sbjct: 314 LSPLKGSVSWTGKPVSYYLHTIDRTILENYFSSLKNPKLREEQEAARRRQQRE 366 >3PPI-A nrPDB Length = 281 Score = 35.4 bits (80), Expect = 0.037, Method: Composition-based stats. Identities = 22/109 (20%), Positives = 40/109 (36%), Gaps = 7/109 (6%) Query: 140 AGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKL-QMAEKLGAAAGF---NYKKE 195 G ++ G G+G A ++ G ++ + +K +A++LG A F N E Sbjct: 29 EGASAIVSGGAGGLGEATVRRLHADGLGVVIADLAAEKGKALADELGNRAEFVSTNVTSE 88 Query: 196 DFSEATLKFTKGAG-VNLILDCIGGSYWEKNVNCLALDGRWVLYGLMGG 243 D A ++ G + + GG + + DG G Sbjct: 89 DSVLAAIEAANQLGRLRYAVVAHGG--FGVAQRIVQRDGSPADMGGFTK 135 >1XLT-A nrPDB Length = 384 Score = 35.0 bits (79), Expect = 0.042, Method: Composition-based stats. Identities = 22/130 (16%), Positives = 39/130 (30%), Gaps = 5/130 (3%) Query: 128 AFQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQMAEKLGAA 187 AF ++ VL+ G+ G AI + GA+ + T + E LG Sbjct: 159 AFPMMMTAAGTVPPARVLVF-GVGVAGLQAIATAKRLGAVVMATDVRAATKEQVESLGGK 217 Query: 188 AGFNYKKEDFSEATLKFTKGAGVNLILDCIGGSYWEKNVNCLALDGRWVLYGLMGGGDIN 247 D T G + + E + L + L+ G Sbjct: 218 FI----TVDDEAMKTAETAGGYAKEMGEEFRKKQAEAVLKELVKTDIAITTALIPGKPAP 273 Query: 248 GPLFSKLLFK 257 + +++ K Sbjct: 274 VLITEEMVTK 283 >5JJC-A nrPDB Length = 342 Score = 35.0 bits (79), Expect = 0.046, Method: Composition-based stats. Identities = 11/60 (18%), Positives = 19/60 (31%), Gaps = 4/60 (6%) Query: 133 HLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAG---SQKKLQMAEKLGAAAG 189 G ++ G V++ G + + G + SQ+K LGA Sbjct: 54 EKRGLLRPGG-VIVEGTAGNTGIGLTMVAKALGYRTAIVIPETASQEKKDALRLLGAELI 112 >3DWF-A nrPDB Length = 276 Score = 35.0 bits (79), Expect = 0.051, Method: Composition-based stats. Identities = 16/55 (29%), Positives = 24/55 (43%), Gaps = 4/55 (7%) Query: 140 AGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQMA----EKLGAAAGF 190 G V++ G+G GA +VTA S++ LQ +LGAA+ Sbjct: 10 QGKKVIVTGASKGIGREIAYHLAKMGAHVVVTARSKEALQKVVARCLELGAASAH 64 >4AEC-A nrPDB Length = 430 Score = 34.7 bits (78), Expect = 0.055, Method: Composition-based stats. Identities = 17/79 (21%), Positives = 32/79 (40%), Gaps = 7/79 (8%) Query: 133 HLVGNVQAGDYVLI--HAGLSGVGTAAIQLTRMAGAIPLVTAG---SQKKLQMAEKLGAA 187 G + G VL+ +G +G+G A I +R G ++T S ++ + + GA Sbjct: 166 EQKGFISPGKSVLVEPTSGNTGIGLAFIAASR--GYRLILTMPASMSMERRVLLKAFGAE 223 Query: 188 AGFNYKKEDFSEATLKFTK 206 + + A K + Sbjct: 224 LVLTDPAKGMTGAVQKAEE 242 >1Q7C-A nrPDB Length = 244 Score = 34.7 bits (78), Expect = 0.063, Method: Composition-based stats. Identities = 20/87 (22%), Positives = 33/87 (37%), Gaps = 8/87 (9%) Query: 140 AGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQMAEKLGAAAGFNYKKEDFSE 199 G L+ G+G A + GA + TA S+ GA A +Y + Sbjct: 4 EGKIALVTGASRGIGRAIAETLAARGAKVIGTATSEN--------GAQAISDYLGANGKG 55 Query: 200 ATLKFTKGAGVNLILDCIGGSYWEKNV 226 L T A + +L+ I + E ++ Sbjct: 56 LMLNVTDPASIESVLEKIRAEFGEVDI 82 >5PGZ-A nrPDB Length = 276 Score = 34.3 bits (77), Expect = 0.074, Method: Composition-based stats. Identities = 15/55 (27%), Positives = 24/55 (43%), Gaps = 4/55 (7%) Query: 140 AGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQMA----EKLGAAAGF 190 G V++ G+G GA ++TA S++ LQ +LGAA+ Sbjct: 17 QGKKVIVTGASKGIGREMAYHLSKMGAHVVLTARSEEGLQKVVSRCLELGAASAH 71 >5YWN-A nrPDB Length = 334 Score = 34.3 bits (77), Expect = 0.081, Method: Composition-based stats. Identities = 13/68 (19%), Positives = 22/68 (32%), Gaps = 8/68 (11%) Query: 143 YVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQMAEKLGAAAGFNYKKEDFSEATL 202 V + + I L G + + S++K +KL DFS + Sbjct: 4 SVFVSGATGYLAQQIIALVLSKGYKVVGSVRSEEKGANLKKLYGD--------DFSYEVV 55 Query: 203 KFTKGAGV 210 K + G Sbjct: 56 KVLEQKGA 63 >5ILO-A nrPDB Length = 271 Score = 34.3 bits (77), Expect = 0.085, Method: Composition-based stats. Identities = 26/133 (19%), Positives = 42/133 (31%), Gaps = 15/133 (11%) Query: 135 VGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQMAEKLGAAAGFNYKK 194 VG G ++ G G+G + AGA + Q L+ KL AA Sbjct: 9 VGTSFRGKNAVVTGGAGGIGLQVSKQLLAAGAAKVAIIDLQDNLEEFVKLRAAH----PT 64 Query: 195 EDFSEATLKFTKGAGVNLILDCIGGSYWEKNVNCLALDGRWVLYGLMGGGDINGPLFSKL 254 + + GV + I ++ G + + G + + L Sbjct: 65 QSVMIIKMDVANKKGVEATYEEIAKTF-----------GNIDIVVNVAGIFNDKDVQRTL 113 Query: 255 LFKRGSLITSLLR 267 L G +I S L Sbjct: 114 LVNLGGIINSTLS 126 >3DLC-A nrPDB Length = 219 Score = 33.9 bits (76), Expect = 0.092, Method: Composition-based stats. Identities = 19/155 (12%), Positives = 47/155 (30%), Gaps = 9/155 (5%) Query: 144 VLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQMAEKLGAAAGFNYKKEDFSEATLK 203 I G G +I L + + S+ ++A K A A N + + Sbjct: 46 TCIDIGSGP-GALSIALAKQSDFSIRALDFSKHMNEIALKNIADANLNDRIQIVQGDVHN 104 Query: 204 FTKGAGVNLILDCIG--------GSYWEKNVNCLALDGRWVLYGLMGGGDINGPLFSKLL 255 ++ G + + + L G+ + G G ++ + ++++ Sbjct: 105 IPIEDNYADLIVSRGSVFFWEDVATAFREIYRILKSGGKTYIGGGFGNKELRDSISAEMI 164 Query: 256 FKRGSLITSLLRSRDNKYKQMLVNAFTEQILPHFS 290 K ++ + + N E + + Sbjct: 165 RKNPDWKEFNRKNISQENVERFQNVLDEIGISSYE 199 >4KRI-A nrPDB Length = 433 Score = 33.9 bits (76), Expect = 0.11, Method: Composition-based stats. Identities = 22/117 (18%), Positives = 36/117 (30%), Gaps = 17/117 (14%) Query: 132 LHLVGNVQAGDYVL-IHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQMAEKL---GAA 187 L G ++ G +L I G+ G A Q G S L +A + Sbjct: 214 LKRFGPMKTGQRMLDIGVGIGGG---ARQAASEFGLQVHGVDLSTNMLAVALERVHKEKD 270 Query: 188 AGFNYKKEDFSEATLKFTKGAGVNLIL--DCI-----GGSYWEKNVNCLALDGRWVL 237 A Y D E + + + DCI + + L G+ ++ Sbjct: 271 ARVTYAVCDACEYEFE---PNSFDYVFSRDCIQHIKDTDKLFSRIYRALKPGGKVLI 324 >1X14-A nrPDB Length = 401 Score = 33.5 bits (75), Expect = 0.12, Method: Composition-based stats. Identities = 28/134 (20%), Positives = 46/134 (34%), Gaps = 12/134 (8%) Query: 135 VGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQMAEKLGAAAGFNYKK 194 G V ++I G G AAI GAI + + + +GA + + Sbjct: 167 AGKVPPAKVMVI--GAGVAGLAAIGAANSLGAIVRAFDTRPEVKEQVQSMGAE----FLE 220 Query: 195 EDFSEATLKFTKGAG-VNLILDCIGGSYWEKNVNCLALDGRWVLYGLMGGGDINGPLFSK 253 DF E + G G ++ D + E V L+ G + + Sbjct: 221 LDFKE---EAGSGDGYAKVMSDAFIKAEMELFAAQAKEVDIIVTTALIPGKPAPKLITRE 277 Query: 254 LL--FKRGSLITSL 265 ++ K GS+I L Sbjct: 278 MVDSMKAGSVIVDL 291 >5B6K-A nrPDB Length = 366 Score = 33.5 bits (75), Expect = 0.13, Method: Composition-based stats. Identities = 8/79 (10%), Positives = 21/79 (26%), Gaps = 7/79 (8%) Query: 143 YVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQMAEKLGAAAGFNYKKEDF-SEAT 201 V + + ++ + + S +K + +K DF E Sbjct: 23 TVFVSGATGFIAQHVVRQLLDQNYKVIGSVRSAEKGDHLKN------VIFKGGDFNYEIV 76 Query: 202 LKFTKGAGVNLILDCIGGS 220 + + + + G Sbjct: 77 KDISDPTAFDHVFEKHGKD 95 >5ITV-A nrPDB Length = 255 Score = 33.5 bits (75), Expect = 0.14, Method: Composition-based stats. Identities = 12/38 (31%), Positives = 18/38 (47%) Query: 142 DYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQ 179 VLI G SG+G AA+Q A +V + + + Sbjct: 8 KTVLITGGASGIGYAAVQAFLGQQANVVVADIDEAQGE 45 >3NJ4-A nrPDB Length = 435 Score = 33.5 bits (75), Expect = 0.14, Method: Composition-based stats. Identities = 11/46 (23%), Positives = 16/46 (34%) Query: 130 QLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQ 175 + +V V + AG VG Q R GA ++T Sbjct: 204 DGIKRATDVMIAGKVAVVAGYGDVGKGCAQALRGFGARVIITEIDP 249 >3T4P-A nrPDB Length = 334 Score = 33.1 bits (74), Expect = 0.16, Method: Composition-based stats. Identities = 9/71 (12%), Positives = 22/71 (30%), Gaps = 3/71 (4%) Query: 125 WLTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAG---SQKKLQMA 181 + G + G +++ + G + L + G ++T S ++ + Sbjct: 55 GFAIYDKAEKEGKLIPGKSIVVESSSGNTGVSLAHLGAIRGYKVIITMPESMSLERRCLL 114 Query: 182 EKLGAAAGFNY 192 GA Sbjct: 115 RIFGAEVILTP 125 >3EMK-A nrPDB Length = 246 Score = 33.1 bits (74), Expect = 0.19, Method: Composition-based stats. Identities = 18/84 (21%), Positives = 33/84 (39%), Gaps = 6/84 (7%) Query: 141 GDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKL-QMAEKLGAAAGFNYKKEDFSE 199 G L+ G+G A + GAI + ++KL ++A +LG E Sbjct: 7 GRKALVTGATGGLGEAIARALHAQGAIVGLHGTREEKLKELAAELGERIFVFPANLSDRE 66 Query: 200 ATLKF-----TKGAGVNLILDCIG 218 A + GV+++++ G Sbjct: 67 AVKALGQKAEEEMGGVDILVNNAG 90 >5T5Q-A nrPDB Length = 247 Score = 32.7 bits (73), Expect = 0.20, Method: Composition-based stats. Identities = 17/84 (20%), Positives = 34/84 (40%), Gaps = 8/84 (9%) Query: 143 YVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQ-MAEKLG-----AAAGFNYKKED 196 +++ G+G A +L +GA ++T ++ L A LG A + D Sbjct: 11 TLVLTGANGGIGRAIAELFHASGANLVLTDLDREGLDAFAASLGSPERIATIKADASSAD 70 Query: 197 FSE--ATLKFTKGAGVNLILDCIG 218 +E L + G++ ++ G Sbjct: 71 DAEKTVALAMERFGGIDFLVPSAG 94 >4AVY-A nrPDB Length = 242 Score = 32.7 bits (73), Expect = 0.21, Method: Composition-based stats. Identities = 17/88 (19%), Positives = 29/88 (32%), Gaps = 13/88 (14%) Query: 131 LLHLVGNVQAGDYVLIHAGLSGVG-TAAIQLTRMAGAIPLVTAGSQKKLQMAEKLGAAAG 189 + ++ AG VL+ G SG+G A+Q GA + A L A Sbjct: 1 GMVFQHDIYAGQQVLVTGGSSGIGAAIAMQFAE-LGAEVV-----------ALGLDADGV 48 Query: 190 FNYKKEDFSEATLKFTKGAGVNLILDCI 217 + L T + + + + Sbjct: 49 HAPRHPRIRREELDITDSQRLQRLFEAL 76 >5CDY-A nrPDB Length = 244 Score = 32.7 bits (73), Expect = 0.23, Method: Composition-based stats. Identities = 21/87 (24%), Positives = 33/87 (37%), Gaps = 8/87 (9%) Query: 140 AGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQMAEKLGAAAGFNYKKEDFSE 199 G L+ G+G A +L GA + TA S+K GA A Y E+ Sbjct: 4 EGKIALVTGASRGIGRAIAELLVERGACVIGTATSEK--------GAEAISAYLGENGKG 55 Query: 200 ATLKFTKGAGVNLILDCIGGSYWEKNV 226 L ++ +L I + E ++ Sbjct: 56 LMLNVVDPTSIDTVLATIRAEFGEVDI 82 >2ISQ-A nrPDB Length = 320 Score = 32.7 bits (73), Expect = 0.24, Method: Composition-based stats. Identities = 16/79 (20%), Positives = 29/79 (36%), Gaps = 7/79 (8%) Query: 133 HLVGNVQAGDYVLI--HAGLSGVGTAAIQLTRMAGAIPLVTAG---SQKKLQMAEKLGAA 187 G ++ G+ VLI +G +GVG A + G ++T S ++ + G Sbjct: 56 EKKGLIKPGESVLIEPTSGNTGVGLAFTAAAK--GYKLIITMPASMSTERRIILLAFGVE 113 Query: 188 AGFNYKKEDFSEATLKFTK 206 + A K + Sbjct: 114 LVLTDPAKGMKGAIAKAEE 132 >4EUF-A nrPDB Length = 418 Score = 32.3 bits (72), Expect = 0.26, Method: Composition-based stats. Identities = 27/188 (14%), Positives = 64/188 (34%), Gaps = 14/188 (7%) Query: 133 HLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAG---AIPLVTAGSQKKLQMAEKLGAAAG 189 + VLI SG G A +++ G A + S + ++G A Sbjct: 52 KKAIGFRGPKKVLIVGASSGFGL-ATRISVAFGGPEAHTIGV--SYETGATDRRIGTAGW 108 Query: 190 FNYKKEDFSEATLKFTKGAGVNLILDCIGGSYWEKNVNCLALDGRWVLYGLMGGGDINGP 249 +N F + K N I D +K + + + +G + + Sbjct: 109 YN---NIFFKEFAKKKGLVAKNFIEDAFSNETKDKVIKYIKDE-----FGKIDLFVYSLA 160 Query: 250 LFSKLLFKRGSLITSLLRSRDNKYKQMLVNAFTEQILPHFSTEGPQRLLPVLDRIYPVTE 309 + +K G++ TS +++ ++ ++ ++I + + ++ + Sbjct: 161 APRRKDYKTGNVYTSRIKTILGDFEGPTIDVERDEITLKKVSSASIEEIEETRKVMGGED 220 Query: 310 IQEAHKYM 317 QE + + Sbjct: 221 WQEWCEEL 228 >1DIR-A nrPDB Length = 241 Score = 32.3 bits (72), Expect = 0.27, Method: Composition-based stats. Identities = 14/81 (17%), Positives = 26/81 (32%), Gaps = 1/81 (1%) Query: 140 AGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQMAEKL-GAAAGFNYKKEDFS 198 VL++ G +G+ +Q R + + A + F + + + Sbjct: 6 EARRVLVYGGRGALGSRCVQAFRARNWWVASIDVVENEEASASVIVKMTDSFTEQADQVT 65 Query: 199 EATLKFTKGAGVNLILDCIGG 219 K V+ IL GG Sbjct: 66 AEVGKLLGDQKVDAILCVAGG 86 >6FOC-D nrPDB Length = 475 Score = 32.3 bits (72), Expect = 0.29, Method: Composition-based stats. Identities = 20/122 (16%), Positives = 39/122 (31%), Gaps = 15/122 (12%) Query: 65 ASGHVAELGPGCQGHW--KIGDTAMALLPGGGQAQYVTVPEGLLMPIPEGLTLTQAAAIP 122 + +G G +GH +GD PG G+ + P + + Sbjct: 83 GASISVPVGDGVKGHVFNALGD--CLDDPGYGKDFE----HWSIHRKPPAFSDLE--PRT 134 Query: 123 EAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQ-----LTRMAGAIPLVTAGSQKK 177 E T +++ L+ G + + G T IQ + R G + ++ Sbjct: 135 EMLETGLKVVDLLTPYVRGGKIALFGGAGVGKTVLIQEMINRIARNFGGTSVFAGVGERT 194 Query: 178 LQ 179 + Sbjct: 195 RE 196 >1HXH-A nrPDB Length = 253 Score = 32.3 bits (72), Expect = 0.33, Method: Composition-based stats. Identities = 14/47 (29%), Positives = 22/47 (46%), Gaps = 1/47 (2%) Query: 140 AGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKK-LQMAEKLG 185 G L+ G SGVG ++L GA + ++ Q+A +LG Sbjct: 5 QGKVALVTGGASGVGLEVVKLLLGEGAKVAFSDINEAAGQQLAAELG 51 >4DIO-A nrPDB Length = 405 Score = 32.0 bits (71), Expect = 0.37, Method: Composition-based stats. Identities = 13/68 (19%), Positives = 20/68 (29%), Gaps = 1/68 (1%) Query: 128 AFQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQMAEKLGAA 187 A ++ + + G G AI R GA+ T + LGA Sbjct: 177 ALPMMMTAAGTVPAAKIFVM-GAGVAGLQAIATARRLGAVVSATDVRPAAKEQVASLGAK 235 Query: 188 AGFNYKKE 195 +E Sbjct: 236 FIAVEDEE 243 >5IJZ-A nrPDB Length = 447 Score = 32.0 bits (71), Expect = 0.38, Method: Composition-based stats. Identities = 36/201 (17%), Positives = 67/201 (33%), Gaps = 33/201 (16%) Query: 78 GHWKIGDTAMALLPGGGQAQY--VTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLV 135 G +G + L Y + + +GLT ++ T + ++ V Sbjct: 167 GDIGVGGREIGYL----FGHYRRMANQHESGVLTGKGLTW--GGSLVRTEATGYGCVYFV 220 Query: 136 GNV--QAGDYV----LIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQ-----------KKL 178 + G+ + +I +G V T AI+ + GA + + S KL Sbjct: 221 SEMIKAKGESISGQKIIVSGSGNVATYAIEKAQELGATVIGFSDSSGWVHTPNGVDVAKL 280 Query: 179 QMAEKLGAAAGFNYKKEDFSEATLKFTKGA----GVNLILDCIGGSYWE-KNVNCLALDG 233 + +++ A Y E E T G+ ++ L C + +N LA +G Sbjct: 281 REIKEVRRARVSVYADE--VEGATYHTDGSIWDLKCDIALPCATQNELNGENAKTLADNG 338 Query: 234 -RWVLYGLMGGGDINGPLFSK 253 R+V G + Sbjct: 339 CRFVAEGANMPSTPEAVEVFR 359 >1BDB-A nrPDB Length = 277 Score = 32.0 bits (71), Expect = 0.41, Method: Composition-based stats. Identities = 15/42 (35%), Positives = 20/42 (47%) Query: 141 GDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQMAE 182 G+ VLI G SG+G A + GA V S ++L E Sbjct: 5 GEAVLITGGASGLGRALVDRFVAEGAKVAVLDKSAERLAELE 46 >4OAU-C nrPDB Length = 699 Score = 31.6 bits (70), Expect = 0.45, Method: Composition-based stats. Identities = 24/175 (13%), Positives = 60/175 (34%), Gaps = 23/175 (13%) Query: 164 AGAIPLVTAGSQKKLQMAEKLGAAAGFNYKKEDFSEATLKFTKGAGVNL-ILDCIGGSYW 222 GA + +++ + K GA A + ++ E G ++ D +G + Sbjct: 127 RGANVNLRRKTKEDQERLRKGGATALMDAAEKGHVEVLKILLDEMGADVNACDNMGRNAL 186 Query: 223 EKNVNCLALDGRWVLYGLMGGGDINGPLFSKLLFKRGSLI--------TSLLRSRDNKYK 274 + + D + + LL G+ + T L+ + + K+ Sbjct: 187 IHAL--------------LSSDDSDVEAITHLLLDHGADVNVRGERGKTPLILAVEKKHL 232 Query: 275 QMLVNAFTEQILPHFSTEGPQRLLPVLDRIYPVTEIQEAHKYMEANKNIGKIVLE 329 ++ ++ + T+ + +L + +I E A+ + G +V+ Sbjct: 233 GLVQRLLEQEHIEINDTDSDGKTALLLAVELKLKKIAELLCKRGASTDCGDLVMT 287 >2YFH-A nrPDB Length = 448 Score = 31.6 bits (70), Expect = 0.45, Method: Composition-based stats. Identities = 35/215 (16%), Positives = 71/215 (33%), Gaps = 30/215 (13%) Query: 72 LGPGCQGHWKIGDTAMALLPGG-GQAQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAF- 129 +GP GD + G QY + G + G + ++ T + Sbjct: 156 IGPDI--DVPAGDLGVGAREIGYMYGQYRKIVGGFYNGVLTGKARSFGGSLIRPEATGYG 213 Query: 130 ------QLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGS--------- 174 +L G G V + +G V AI+ GA + + S Sbjct: 214 LVYFTEAMLKRHGMGFEGMRVSV-SGSGNVAQYAIEKAMEFGARVITASDSSGTVVDESG 272 Query: 175 --QKKLQMAEKLGAA---AGFNYKKE-DFSEATLKFTKGAGVNLILDCIGGSYWE-KNVN 227 ++KL ++ A+ +Y KE + V++ L C + + + Sbjct: 273 FTKEKLARLIEIKASRDGRVADYAKEFGLVYLEGQQPWSLPVDIALPCATQNELDVDAAH 332 Query: 228 CLALDGRWVLYGLMGGGDINGPLFSKLLFKRGSLI 262 L +G + G ++ + + LF++ ++ Sbjct: 333 QLIANGVKAV---AEGANMPTTIEATELFQQAGVL 364 >1AE1-A nrPDB Length = 273 Score = 31.6 bits (70), Expect = 0.46, Method: Composition-based stats. Identities = 16/77 (20%), Positives = 28/77 (36%), Gaps = 2/77 (2%) Query: 141 GDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQMAEKLGAAAGFN--YKKEDFS 198 G L+ G G+G A ++ GA + ++K+L ++ G N D Sbjct: 21 GTTALVTGGSKGIGYAIVEELAGLGARVYTCSRNEKELDECLEIWREKGLNVEGSVCDLL 80 Query: 199 EATLKFTKGAGVNLILD 215 T + V + D Sbjct: 81 SRTERDKLMQTVAHVFD 97 >3WMF-A nrPDB Length = 621 Score = 31.6 bits (70), Expect = 0.50, Method: Composition-based stats. Identities = 22/112 (19%), Positives = 33/112 (29%), Gaps = 11/112 (9%) Query: 57 ASNILGLEASGHVAELGPGCQGHWKIG-------DTAMALLPGGGQAQYVTVPEGLLMPI 109 S ILG G A++ P G D A+ VT P + + Sbjct: 292 FSAILGFMGVGQAAQVWPDVTRGLGAGGELFAMIDRVPQYRRPDPGAEVVTQP----LVL 347 Query: 110 PEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLT 161 +G+ + L + + G V I G + IQL Sbjct: 348 KQGIVFENVHFRYPTRMNVEVLRGISLTIPNGKTVAIVGGSGAGKSTIIQLL 399 >3UXA-A nrPDB Length = 252 Score = 31.6 bits (70), Expect = 0.50, Method: Composition-based stats. Identities = 14/79 (17%), Positives = 24/79 (30%), Gaps = 5/79 (6%) Query: 160 LTRMAGAIPLVTAGSQKKLQMAEKLGAAAGFNYKK-----EDFSEATLKFTKGAGVNLIL 214 R G P + ++ L +A ++GA + E E K N++ Sbjct: 148 YARSYGMEPAIVINDEEDLDIALRIGARIIIISSRDLETLEINKENQRKLISMIPSNVVK 207 Query: 215 DCIGGSYWEKNVNCLALDG 233 G + L G Sbjct: 208 VAASGISERNEIEELRKLG 226 >3VPX-A nrPDB Length = 364 Score = 31.6 bits (70), Expect = 0.54, Method: Composition-based stats. Identities = 14/51 (27%), Positives = 24/51 (47%), Gaps = 2/51 (3%) Query: 140 AGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQMA-EKLGAAAG 189 AG V + G+ V A + GA ++T +++ +Q A + GA A Sbjct: 172 AGKTVAVQ-GVGNVAYALCEYLHEEGAKLIITDINEEAVQRAVDAFGATAV 221 >3OND-A nrPDB Length = 488 Score = 31.6 bits (70), Expect = 0.55, Method: Composition-based stats. Identities = 12/46 (26%), Positives = 16/46 (34%) Query: 130 QLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQ 175 L +V V + AG VG + AGA +VT Sbjct: 253 DGLMRATDVMIAGKVAVVAGYGDVGKGCAAALKQAGARVIVTEIDP 298 >3GDF-A nrPDB Length = 267 Score = 31.6 bits (70), Expect = 0.55, Method: Composition-based stats. Identities = 22/115 (19%), Positives = 41/115 (35%), Gaps = 13/115 (11%) Query: 127 TAFQLLHLVGNVQAGDYVLIHAGLS--GVGTAAIQLTRMAGAIPLVTAGSQKKLQM--AE 182 T + L +++ G V++ G+G A + GA +T S+ + + Sbjct: 7 TKHESLLDQLSLK-GKVVVVTGASGPKGMGIEAARGCAEMGAAVAITYASRAQGAEENVK 65 Query: 183 KLGAAAGFNYK----KEDFSEATLKFTKGAGVNLILDCIGGSYWEKNVNCLALDG 233 +L G K + D E+ K K +++ D + N A G Sbjct: 66 ELEKTYGIKAKAYKCQVDSYESCEKLVK----DVVADFGQIDAFIANAGATADSG 116 >3VZS-A nrPDB Length = 257 Score = 31.2 bits (69), Expect = 0.59, Method: Composition-based stats. Identities = 15/83 (18%), Positives = 30/83 (36%), Gaps = 10/83 (12%) Query: 146 IHAGLSGVGTAAIQLTRMAGAIPLVTAG-----SQKKLQMAEKLGAAAGFNYKKEDFSEA 200 + G+ G+GTA Q G + G +K L+ + LG + ++ Sbjct: 19 VTGGMGGIGTAICQRLAKDGFRVVAGCGPNSPRREKWLEQQKALGFDFIASEGNVADWDS 78 Query: 201 TLKFTKGAG-----VNLILDCIG 218 T V+++++ G Sbjct: 79 TKTAFDKVKSEVGEVDVLINNAG 101 >4M8S-A nrPDB Length = 248 Score = 31.2 bits (69), Expect = 0.61, Method: Composition-based stats. Identities = 18/87 (20%), Positives = 35/87 (40%), Gaps = 9/87 (10%) Query: 140 AGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQ-----MAEKLGAAAGFNYKK 194 +G L+ G+G A AGA + TA S+ +A+ G N + Sbjct: 7 SGKIALVTGASRGIGAAIADTLAAAGAKVIGTATSESGAAAISERLAQWGGEGRVLNSAE 66 Query: 195 EDFSEAT---LKFTKGAGVNLILDCIG 218 + E ++ T G ++++++ G Sbjct: 67 PETVENLIADIEKTFGK-LDILVNNAG 92 >2NNL-D nrPDB Length = 337 Score = 31.2 bits (69), Expect = 0.70, Method: Composition-based stats. Identities = 5/43 (11%), Positives = 13/43 (30%) Query: 142 DYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQMAEKL 184 + V + +G+ + G T ++ + L Sbjct: 6 ETVCVTGASGFIGSWLVMRLLERGYTVRATVRDPTNVKKVKHL 48 >5B1I-A nrPDB Length = 311 Score = 30.8 bits (68), Expect = 0.77, Method: Composition-based stats. Identities = 15/59 (25%), Positives = 24/59 (40%), Gaps = 1/59 (1%) Query: 147 HAGLSGVGTA-AIQLTRMAGAIPLVTAGSQKKLQMAEKLGAAAGFNYKKEDFSEATLKF 204 AG +G+G A A Q + + + S +K + + LGA +E A K Sbjct: 69 TAGNTGIGLALATQAHHLRTILVVPEKFSMEKQVLMQALGAEIVHTPSEEGIKGAIRKA 127 >4K2X-A nrPDB Length = 523 Score = 30.8 bits (68), Expect = 0.78, Method: Composition-based stats. Identities = 12/44 (27%), Positives = 19/44 (43%) Query: 145 LIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQMAEKLGAAA 188 ++ AG G R+AGA LV + + ++ LG A Sbjct: 25 VVIAGAGPTGLMLACELRLAGARTLVLERLAEPVDFSKALGVHA 68 >4HP8-A nrPDB Length = 247 Score = 30.8 bits (68), Expect = 0.84, Method: Composition-based stats. Identities = 19/82 (23%), Positives = 31/82 (37%), Gaps = 4/82 (4%) Query: 140 AGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQM---AEKLGAAAGFNYKKED 196 G L+ +G+G A AGA + A + A+ G A+ D Sbjct: 8 EGRKALVTGANTGLGQAIAVGLAAAGAEVVCAARRAPDETLDIIAKDGGNASALLIDFAD 67 Query: 197 FSEATLKFTKGAGVNLILDCIG 218 A FT AG +++++ G Sbjct: 68 PLAAKDSFTD-AGFDILVNNAG 88 >6GBN-A nrPDB Length = 438 Score = 30.8 bits (68), Expect = 0.88, Method: Composition-based stats. Identities = 16/107 (14%), Positives = 33/107 (30%), Gaps = 12/107 (11%) Query: 132 LHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQMAEKLGAAAGFN 191 + +V V + AG VG + R AGA +VT + + Sbjct: 209 IRRATDVMMAGKVAVVAGYGDVGKGSAASLRGAGARVIVTEI-DPICALQAAMDGYEV-- 265 Query: 192 YKKEDFSEATLKFTKGAGVNLILDCIGGSYWEKNVNCLALDGRWVLY 238 K D + ++++ G + A+ + ++ Sbjct: 266 KKMADAVKR---------ADIVVTATGNKNIITGEHFKAMRDKVIVC 303 >6GCS-E nrPDB Length = 375 Score = 30.8 bits (68), Expect = 0.89, Method: Composition-based stats. Identities = 14/91 (15%), Positives = 30/91 (32%), Gaps = 2/91 (2%) Query: 139 QAGDYVLIHAGLSGVGTAAIQ-LTRMAGAIPLVTAGSQKKLQMAEKLGAAAGFNYKKEDF 197 + G + +G+ L + G +V + + + G N+ + D Sbjct: 51 RTGYTATVFGANGFLGSYLTAKLAKH-GTTVVVPYREEMAKRHLKVTGDLGVVNFLEMDL 109 Query: 198 SEATLKFTKGAGVNLILDCIGGSYWEKNVNC 228 +++++ IG Y KN N Sbjct: 110 RNLESIDEAVRHSDIVVNLIGREYETKNFNY 140 >4LIS-A nrPDB Length = 371 Score = 30.8 bits (68), Expect = 0.92, Method: Composition-based stats. Identities = 16/77 (20%), Positives = 27/77 (35%), Gaps = 4/77 (5%) Query: 140 AGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQMAEKLGAAAGFNYKKEDFSE 199 VL+ G +G+ AG +V AE L + KK +F++ Sbjct: 2 PSGSVLVTGGTGYIGSFTTLALLEAGYKVVVADNLYNSS--AEALNRIELISGKKAEFAQ 59 Query: 200 ATLKFTKGAGVNLILDC 216 L T A + + + Sbjct: 60 --LDVTDEAAFDKVFEA 74 >4FIO-A nrPDB Length = 354 Score = 30.8 bits (68), Expect = 0.92, Method: Composition-based stats. Identities = 34/203 (16%), Positives = 60/203 (29%), Gaps = 29/203 (14%) Query: 64 EASGHVAELGPGCQGHWKIGDTAMALLPGGGQAQYVTVPEGLLMPIPEGLTLTQAAAIPE 123 E V + G G +K G + GG A IP L+ + A Sbjct: 63 ENGATVIDCGVNVAGSFKAG-ELYTKVCLGGLADVGIS-------IPGDLS-EKFALPSV 113 Query: 124 AWLTAFQLLHLVGNVQAGDYVLIHA----GLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQ 179 T F + +G +AG V + G R P A + +++ Sbjct: 114 KIKTDFPAISTLGAQKAGWSVSVGDFFALGSGP--------ARALSLKP---AETYEEID 162 Query: 180 MAEKLGAAAGFNYKKEDFS---EATLKFTKGAGVNLILDCIGGSYWEKNVNCLALDGRWV 236 ++ A + D + GV++ + + V + + GR V Sbjct: 163 YKDE--ADLAILTLEADVLPGEDVAQYIADECGVDVANVFLLVAPTASLVGSIQIAGRVV 220 Query: 237 LYGLMGGGDINGPLFSKLLFKRG 259 G + K++ G Sbjct: 221 ENGTYKMLEFLKFDVKKVVHAAG 243 >5EES-A nrPDB Length = 247 Score = 30.8 bits (68), Expect = 0.95, Method: Composition-based stats. Identities = 12/86 (13%), Positives = 28/86 (32%), Gaps = 4/86 (4%) Query: 141 GDYVLIHAGLSGVGTAAIQLTRMAG-AIPLVTAGSQKKLQMAEKLGAAAGFNYKKEDFSE 199 G V + VG + + + G L + GA ++ + Sbjct: 1 GIKVGVLGAKGRVGQTIVAAVNESDDLELVAEIGVDDDLSLLVDNGAEVVVDFTTPNAVM 60 Query: 200 ATLKFTKGAGVNLILDCIGGSYWEKN 225 L+F G++ + +G + ++ Sbjct: 61 GNLEFCINNGISAV---VGTTGFDDA 83 >2Q2Q-A nrPDB Length = 255 Score = 30.4 bits (67), Expect = 1.00, Method: Composition-based stats. Identities = 16/85 (18%), Positives = 30/85 (35%), Gaps = 7/85 (8%) Query: 141 GDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQMAE--KLGAAAGFNYKKEDFS 198 G L+ SG+G Q+ AGA ++ +AE + G A + Sbjct: 4 GKTALVTGSTSGIGLGIAQVLARAGANIVLNGFGDPAPALAEIARHGVKAVHHPADLSDV 63 Query: 199 EATLKFT-----KGAGVNLILDCIG 218 + GV+++++ G Sbjct: 64 AQIEALFALAEREFGGVDILVNNAG 88 >3F4W-A nrPDB Length = 211 Score = 30.4 bits (67), Expect = 1.1, Method: Composition-based stats. Identities = 22/158 (13%), Positives = 49/158 (31%), Gaps = 20/158 (12%) Query: 108 PIPEGLTLTQAAA--IPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAG 165 + + + + + + + A + + + VL A + G QL AG Sbjct: 21 KVVDDVDIIEVGTPFLIREGVNAIKAIKEKYPHKE---VLADAKIMDGGHFESQLLFDAG 77 Query: 166 AIPLVTAGSQKKL------QMAEKLGAAAGFNYKKEDFSEATLKFTKGAGVNLIL----- 214 A + G L + A++ G + D A ++ + AG +++ Sbjct: 78 ADYVTVLGVTDVLTIQSCIRAAKEAGKQVVVDMICVDDLPARVRLLEEAGADMLAVHTGT 137 Query: 215 --DCIGGSYWEKNVNCL--ALDGRWVLYGLMGGGDING 248 G + + L R + G + + Sbjct: 138 DQQAAGRKPIDDLITMLKVRRKARIAVAGGISSQTVKD 175 >3GRP-A nrPDB Length = 266 Score = 30.4 bits (67), Expect = 1.1, Method: Composition-based stats. Identities = 15/84 (17%), Positives = 32/84 (38%), Gaps = 6/84 (7%) Query: 141 GDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKL-QMAEKLGAAAGFNYKKEDFSE 199 G L+ G+G A + GAI + + KL ++A LG + Sbjct: 27 GRKALVTGATGGIGEAIARCFHAQGAIVGLHGTREDKLKEIAADLGKDVFVFSANLSDRK 86 Query: 200 ATLKFT-----KGAGVNLILDCIG 218 + + + G++++++ G Sbjct: 87 SIKQLAEVAEREMEGIDILVNNAG 110 >6C55-A nrPDB Length = 340 Score = 30.4 bits (67), Expect = 1.1, Method: Composition-based stats. Identities = 9/78 (11%), Positives = 24/78 (30%), Gaps = 1/78 (1%) Query: 125 WLTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQMAEKL 184 T + + + G + + G G A Q + G ++ + A++ Sbjct: 1 MTTVYYDQDVKTDALQGKKIAVV-GYGSQGHAHAQNLKDNGYDVVIGIRPGRSFDKAKED 59 Query: 185 GAAAGFNYKKEDFSEATL 202 G + ++ + Sbjct: 60 GFDVFPVAEAVKQADVIM 77 >3RWB-A nrPDB Length = 247 Score = 30.4 bits (67), Expect = 1.1, Method: Composition-based stats. Identities = 13/87 (14%), Positives = 28/87 (32%), Gaps = 10/87 (11%) Query: 140 AGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKL--------QMAEKLGAAAGFN 191 AG L+ G+G A GA +V+ + + + A + A Sbjct: 5 AGKTALVTGAAQGIGKAIAARLAADGATVIVSDINAEGAKAAAASIGKKARAIAADISDP 64 Query: 192 YKKEDFSEATLKFTKGAGVNLILDCIG 218 + T G++++++ Sbjct: 65 GSVKALFAEIQALTG--GIDILVNNAS 89 >2B4Q-A nrPDB Length = 276 Score = 30.4 bits (67), Expect = 1.2, Method: Composition-based stats. Identities = 14/48 (29%), Positives = 19/48 (39%), Gaps = 1/48 (2%) Query: 140 AGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKL-QMAEKLGA 186 AG L+ G G+G Q AGA + A + A +L A Sbjct: 28 AGRIALVTGGSRGIGQMIAQGLLEAGARVFICARDAEACADTATRLSA 75 >4FHN-X nrPDB Length = 450 Score = 30.4 bits (67), Expect = 1.2, Method: Composition-based stats. Identities = 26/162 (16%), Positives = 57/162 (35%), Gaps = 21/162 (12%) Query: 117 QAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGS-- 174 +A + T +L G G V + +G V AI+ GA + + S Sbjct: 212 EATGYGLVYFT-EAMLKRHGMGFEGMRVSV-SGSGNVAQYAIEKAMEFGARVITASDSSG 269 Query: 175 ---------QKKLQMAEKLGAA---AGFNYKKE-DFSEATLKFTKGAGVNLILDCIGGSY 221 ++KL ++ ++ +Y KE + V++ L C + Sbjct: 270 TVVDESGFTKEKLARLIEIKSSRDGRVADYAKEFGLVYLEGQQPWSVPVDIALPCATQNE 329 Query: 222 WE-KNVNCLALDGRWVLYGLMGGGDINGPLFSKLLFKRGSLI 262 + + L +G + G ++ + + LF++ ++ Sbjct: 330 LDVDAAHQLIANGVKAV---AEGANMPTTIEATELFQQAGVL 368 >1V9L-A nrPDB Length = 421 Score = 30.4 bits (67), Expect = 1.3, Method: Composition-based stats. Identities = 13/76 (17%), Positives = 22/76 (28%), Gaps = 3/76 (3%) Query: 100 TVPEGLLMPIPEGL--TLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAA 157 VP PE + + A + ++ + G V I G+ VG Sbjct: 167 NVPGVFTSKPPELWGNPVREYATGFGVAVATREMAKKLWGGIEGKTVAIQ-GMGNVGRWT 225 Query: 158 IQLTRMAGAIPLVTAG 173 GA + + Sbjct: 226 AYWLEKMGAKVIAVSD 241 >4R1U-A nrPDB Length = 349 Score = 30.0 bits (66), Expect = 1.3, Method: Composition-based stats. Identities = 14/72 (19%), Positives = 24/72 (33%), Gaps = 4/72 (5%) Query: 132 LHLVGNVQAGD-YVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGS--QKKLQMAEKL-GAA 187 L +V GD V + + + ++L G T + K ++L GA Sbjct: 17 LDNTSSVSGGDQTVCVTGAGGFIASWLVKLLLERGYTVRGTVRNPEDPKNGHLKELEGAR 76 Query: 188 AGFNYKKEDFSE 199 K D + Sbjct: 77 ERLTLHKVDLLD 88 >6GME-A nrPDB Length = 201 Score = 30.0 bits (66), Expect = 1.3, Method: Composition-based stats. Identities = 19/100 (19%), Positives = 35/100 (35%), Gaps = 11/100 (11%) Query: 130 QLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQMAEKLGAAAG 189 Q ++ + GD V+I G + +++ I ++ + A LGA Sbjct: 23 QAEKMMETMDQGD-VIIRPSSKGENHLTVTW-KVSDGIYQHVDVREEGKENAFSLGATLW 80 Query: 190 FNYKK-EDFSEATLKFTKGAG--------VNLILDCIGGS 220 N ++ ED E ++ + DC GG Sbjct: 81 INSEEFEDLDEIVARYVQPMASFARDLLNHKYYQDCSGGD 120 >1URG-A nrPDB Length = 402 Score = 30.0 bits (66), Expect = 1.4, Method: Composition-based stats. Identities = 19/132 (14%), Positives = 38/132 (28%), Gaps = 26/132 (19%) Query: 134 LVGNVQAGDYVLIHAGLSG-----VGTAAIQLTRMAGAIPLVTAGSQKKLQMAEKLGAAA 188 + G + + + +G V A Q + G +V S Sbjct: 22 EASALPKGQTITVWSWQTGPELQDVKQIAAQWAKAHGDKVIVVDQSS------------- 68 Query: 189 GFNYKKEDFSEATLKFTKGAGVNLIL---DCIGGSYWEKNVNCLALDGRWVLYGLMGGGD 245 N K F + G G +++ G + E+ + G + GL Sbjct: 69 --NPKGFQFYATAART--GKGPDVVFGMPHDNNGVFAEEGLMAPVPSG-VLNTGLYAPNT 123 Query: 246 INGPLFSKLLFK 257 I+ + ++ Sbjct: 124 IDAIKVNGTMYS 135 >3L9X-A nrPDB Length = 413 Score = 29.6 bits (65), Expect = 1.7, Method: Composition-based stats. Identities = 15/93 (16%), Positives = 32/93 (34%), Gaps = 6/93 (6%) Query: 141 GDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQMAEKLGAAAGF-NYKKEDFSE 199 G V+I AG G +L +G +V ++ K G + + + D Sbjct: 4 GMRVII-AGFGRFGQITGRLLLSSGVKMVVLDHDPDHIETLRKFGMKVFYGDATRMD--- 59 Query: 200 ATLKFTKGAGVNLILDCIGGSYWEKNVNCLALD 232 L+ A ++++ I + + + Sbjct: 60 -LLESAGAAKAEVLINAIDDPQTNLQLTEMVKE 91 >3TC6-A nrPDB Length = 258 Score = 29.6 bits (65), Expect = 1.8, Method: Composition-based stats. Identities = 16/80 (20%), Positives = 26/80 (32%), Gaps = 7/80 (8%) Query: 160 LTRMAGAIPLVTAGSQKKLQMAEKLGAAAGFNYKKEDFS------EATLKFTKGAGVNLI 213 R G PL+ + L +A ++GA + D+ E K N++ Sbjct: 148 YARSYGMEPLIVINDENDLDIALRIGA-RFIGIESRDWETLEINKENQRKLISMIPSNVV 206 Query: 214 LDCIGGSYWEKNVNCLALDG 233 I G + L G Sbjct: 207 KVAIAGISERNEIEELRKLG 226 >2UVD-A nrPDB Length = 246 Score = 29.6 bits (65), Expect = 1.8, Method: Composition-based stats. Identities = 19/88 (21%), Positives = 36/88 (40%), Gaps = 10/88 (11%) Query: 141 GDYVLIHAGLSGVG-TAAIQLTRMAGAIPLVTAGSQKKLQMA----EKLGAAAGFNY--- 192 G L+ G+G AI L + + + AG+++K +KLG+ A Sbjct: 4 GKVALVTGASRGIGRAIAIDLAKQGANVVVNYAGNEQKANEVVDEIKKLGSDAIAVRADV 63 Query: 193 -KKEDFSEATLKFTKGAG-VNLILDCIG 218 ED + + G V+++++ G Sbjct: 64 ANAEDVTNMVKQTVDVFGQVDILVNNAG 91 >4R1T-A nrPDB Length = 337 Score = 29.3 bits (64), Expect = 2.2, Method: Composition-based stats. Identities = 11/88 (12%), Positives = 23/88 (26%), Gaps = 3/88 (3%) Query: 140 AGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAG--SQKKLQMAEKL-GAAAGFNYKKED 196 +G V + + + +++ G T K +L GA K D Sbjct: 9 SGQVVCVTGAGGFIASWLVKILLEKGYTVRGTVRNPDDPKNGHLRELEGAKERLTLCKAD 68 Query: 197 FSEATLKFTKGAGVNLILDCIGGSYWEK 224 + G + + + Sbjct: 69 LLDYQSLREAINGCDGVFHTASPVTDDP 96 >5YSS-A nrPDB Length = 256 Score = 29.3 bits (64), Expect = 2.3, Method: Composition-based stats. Identities = 15/85 (17%), Positives = 30/85 (35%), Gaps = 7/85 (8%) Query: 141 GDYVLIHAGLSGVGTAAIQLTRMAGAIPL--VTAGSQKKLQMAEKLGAA---AGFNYKKE 195 G L+ SG+G Q+ AGA + + G G + E Sbjct: 5 GKTALVTGSTSGIGLGIAQVLAQAGATLILNGFGDVDAAKDAVAQYGKTPGYHGADLSDE 64 Query: 196 DFSEATLKFTKGA--GVNLILDCIG 218 +++ + GV+++++ G Sbjct: 65 AQIADMMRYAESEFGGVDILINNAG 89 >2O23-A nrPDB Length = 265 Score = 29.3 bits (64), Expect = 2.3, Method: Composition-based stats. Identities = 22/90 (24%), Positives = 36/90 (40%), Gaps = 6/90 (6%) Query: 145 LIHAGLSGVGTAAIQLTRMAGAIPLVTA-GSQKKLQMAEKLGAAAGF---NYKKEDFSEA 200 +I G SG+G A + GA ++ + A+KLG F + E + Sbjct: 16 VITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTSEKDVQT 75 Query: 201 TLKFTKGA--GVNLILDCIGGSYWEKNVNC 228 L KG V++ ++C G + K N Sbjct: 76 ALALAKGKFGRVDVAVNCAGIAVASKTYNL 105 >2XOK-D nrPDB Length = 511 Score = 29.3 bits (64), Expect = 2.4, Method: Composition-based stats. Identities = 12/96 (12%), Positives = 31/96 (32%), Gaps = 8/96 (8%) Query: 114 TLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQ-----LTRMAGAIP 168 + + + E T +++ L+ G + + G T IQ + + G Sbjct: 156 SFAEQSTSAEILETGIKVVDLLAPYARGGKIGLFGGAGVGKTVFIQELINNIAKAHGGFS 215 Query: 169 LVT---AGSQKKLQMAEKLGAAAGFNYKKEDFSEAT 201 + T +++ + ++ N + E Sbjct: 216 VFTGVGERTREGNDLYREMKETGVINLEGESKVALV 251 >4B4O-A nrPDB Length = 298 Score = 29.3 bits (64), Expect = 2.5, Method: Composition-based stats. Identities = 13/68 (19%), Positives = 22/68 (32%), Gaps = 7/68 (10%) Query: 144 VLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQ-------KKLQMAEKLGAAAGFNYKKED 196 VL+ G +GTA QL G + + +L + A N E+ Sbjct: 3 VLVGGGTGFIGTALTQLLNARGHEVTLVSRKPGPGRITWDELAASGLPSCDAAVNLAGEN 62 Query: 197 FSEATLKF 204 ++ Sbjct: 63 ILNPLRRW 70 >1CYD-A nrPDB Length = 244 Score = 28.9 bits (63), Expect = 2.8, Method: Composition-based stats. Identities = 11/80 (13%), Positives = 27/80 (33%), Gaps = 1/80 (1%) Query: 140 AGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKL-QMAEKLGAAAGFNYKKEDFS 198 +G L+ G+G ++ +GA + + L +A++ D+ Sbjct: 6 SGLRALVTGAGKGIGRDTVKALHASGAKVVAVTRTNSDLVSLAKECPGIEPVCVDLGDWD 65 Query: 199 EATLKFTKGAGVNLILDCIG 218 V+L+++ Sbjct: 66 ATEKALGGIGPVDLLVNNAA 85 >3ORF-A nrPDB Length = 251 Score = 28.9 bits (63), Expect = 2.9, Method: Composition-based stats. Identities = 20/155 (12%), Positives = 49/155 (31%), Gaps = 16/155 (10%) Query: 142 DYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQ-KKLQMAEKLGAAAGFNYKKEDFSEA 200 +L+ G +G ++ + + + + + + +E+ Sbjct: 23 KNILVLGGSGALGAEVVKFFKSKSWNTISIDFRENPNADHSFTIK-----DSGEEEIKSV 77 Query: 201 TLKF-TKGAGVNLILDCIGG-----SYWEKNVNCLALDGRWVLYGLMGGGDINGPLFSKL 254 K +K V+ + GG + ++ + + LY I +KL Sbjct: 78 IEKINSKSIKVDTFVCAAGGWSGGNASSDEFLKSVKGMIDMNLYSAFASAHIG----AKL 133 Query: 255 LFKRGSLITSLLRSRDNKYKQMLVNAFTEQILPHF 289 L + G + + + N+ M+ T+ H Sbjct: 134 LNQGGLFVLTGASAALNRTSGMIAYGATKAATHHI 168 >2VHY-A nrPDB Length = 377 Score = 28.9 bits (63), Expect = 3.0, Method: Composition-based stats. Identities = 18/80 (22%), Positives = 30/80 (37%), Gaps = 12/80 (15%) Query: 109 IPEGLTLTQAAAIPEAWLTAFQLLHLVGN----------VQAGDYVLIHAGLSGVGTAAI 158 +P +++ A A + A+ L+ G V+ D V+I G G A Sbjct: 127 LPLLAPMSEVAGRLAAQVGAYHLMRTQGGRGVLMGGVPGVEPADVVVI--GAGTAGYNAA 184 Query: 159 QLTRMAGAIPLVTAGSQKKL 178 ++ GA V + KL Sbjct: 185 RIANGMGATVTVLDINIDKL 204 >1BW9-B nrPDB Length = 356 Score = 28.9 bits (63), Expect = 3.0, Method: Composition-based stats. Identities = 17/49 (34%), Positives = 22/49 (44%), Gaps = 1/49 (2%) Query: 141 GDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQMAEKLGAAAG 189 G VL+ GL VG + L AGA LV +++ A LG A Sbjct: 176 GLTVLVQ-GLGAVGGSLASLAAEAGAQLLVADTDTERVAHAVALGHTAV 223 >3EZL-A nrPDB Length = 256 Score = 28.9 bits (63), Expect = 3.2, Method: Composition-based stats. Identities = 10/47 (21%), Positives = 20/47 (42%), Gaps = 5/47 (10%) Query: 146 IHAGLSGVGTAAIQLTRMAGAIPLVTAG--SQKKLQMA---EKLGAA 187 + G+ G+GT+ Q G + G S ++++ + LG Sbjct: 18 VTGGMGGIGTSICQRLHKDGFRVVAGCGPNSPRRVKWLEDQKALGFD 64 >5FL7-D nrPDB Length = 509 Score = 28.9 bits (63), Expect = 3.4, Method: Composition-based stats. Identities = 13/96 (13%), Positives = 31/96 (32%), Gaps = 8/96 (8%) Query: 114 TLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQ-----LTRMAGAIP 168 T + + E T +++ L+ G + + G T IQ + + G Sbjct: 154 TFAEQSTTAEVLETGIKVVDLLAPYARGGKIGLFGGAGVGKTVFIQELINNIAKAHGGFS 213 Query: 169 L---VTAGSQKKLQMAEKLGAAAGFNYKKEDFSEAT 201 + V +++ + ++ N + E Sbjct: 214 VFCGVGERTREGNDLYREMKETGVINLEGESKVTLV 249 >5UJU-A nrPDB Length = 576 Score = 28.9 bits (63), Expect = 3.5, Method: Composition-based stats. Identities = 11/64 (17%), Positives = 25/64 (39%), Gaps = 5/64 (7%) Query: 168 PLVTAGSQKKLQMAEKLGAAA-----GFNYKKEDFSEATLKFTKGAGVNLILDCIGGSYW 222 + T + + L +A ++ A +D +A + GV L ++ GG + Sbjct: 463 VIATDSTAQSLDLAGEIAAEHGALTLSVYSTADDVIDAAHEAAVRGGVALSINLTGGVFV 522 Query: 223 EKNV 226 ++ Sbjct: 523 NQSA 526 >2P91-A nrPDB Length = 285 Score = 28.9 bits (63), Expect = 3.5, Method: Composition-based stats. Identities = 11/68 (16%), Positives = 27/68 (39%), Gaps = 7/68 (10%) Query: 169 LVTAGSQKKLQ--MAEKL---GAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIGGSYWE 223 + +++ + +A+ GA F Y + + KG G +L++ C + Sbjct: 26 ITGVANERSIAYGIAKSFHREGAQLAFTYATPKLEKRVREIAKGFGSDLVVKC--DVSLD 83 Query: 224 KNVNCLAL 231 +++ L Sbjct: 84 EDIKNLKK 91 >2DVL-A nrPDB Length = 372 Score = 28.9 bits (63), Expect = 3.7, Method: Composition-based stats. Identities = 12/47 (25%), Positives = 20/47 (42%) Query: 150 LSGVGTAAIQLTRMAGAIPLVTAGSQKKLQMAEKLGAAAGFNYKKED 196 VG AA + GA + A ++++ Q +KL +K D Sbjct: 234 SGRVGVAAQAVGIARGAFEIAKAYAEEREQFGKKLKEHQAIAFKIAD 280 >2EEZ-A nrPDB Length = 369 Score = 28.5 bits (62), Expect = 3.8, Method: Composition-based stats. Identities = 17/97 (17%), Positives = 36/97 (37%), Gaps = 3/97 (3%) Query: 143 YVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQMAEKL--GAAAGFNYKKEDFSEA 200 V+I G VGT A ++ GA + + K+LQ + + G + + ++ Sbjct: 168 SVVILGG-GTVGTNAAKIALGMGAQVTILDVNHKRLQYLDDVFGGRVITLTATEANIKKS 226 Query: 201 TLKFTKGAGVNLILDCIGGSYWEKNVNCLALDGRWVL 237 G L+ +++ L +G ++ Sbjct: 227 VQHADLLIGAVLVPGAKAPKLVTRDMLSLMKEGAVIV 263 >4OMU-A nrPDB Length = 283 Score = 28.5 bits (62), Expect = 4.0, Method: Composition-based stats. Identities = 17/112 (15%), Positives = 36/112 (32%), Gaps = 12/112 (10%) Query: 140 AGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQ-MAEKLGAAAGFNYKKEDFS 198 AG +LI V + ++ + +K + +A + + Sbjct: 118 AGKRILILGAGGAVRGVLEPILAHKPQSLVIANRTVEKAEQLAREFDELGPVVASGFAWL 177 Query: 199 EATLKFTKGAGVNLILDCIGGSYWEK---NVNCLALDGRWVLYGLMGGGDIN 247 + V++I++ S + + L GR V Y +M G + Sbjct: 178 QE--------PVDVIINATSASLAGELPPIADSLVEAGRTVCYDMMYGKEPT 221 >1ZZE-A nrPDB Length = 342 Score = 28.5 bits (62), Expect = 4.1, Method: Composition-based stats. Identities = 11/50 (22%), Positives = 17/50 (34%) Query: 134 LVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQMAEK 183 + G VL+ V + ++ G TA S KL +K Sbjct: 4 DNAVLPEGSLVLVTGANGFVASHVVEQLLEHGYKVRGTARSASKLANLQK 53 >1OOE-A nrPDB Length = 236 Score = 28.5 bits (62), Expect = 4.4, Method: Composition-based stats. Identities = 15/78 (19%), Positives = 32/78 (41%), Gaps = 3/78 (3%) Query: 144 VLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQMAEKLGAAAGFNYKKED--FSEAT 201 V+++ G +G+A ++ + G L S + L N+ +++ E T Sbjct: 6 VIVYGGKGALGSAILEFFKKNGYTVLNIDLSANDQADSNIL-VDGNKNWTEQEQSILEQT 64 Query: 202 LKFTKGAGVNLILDCIGG 219 +G+ V+ + GG Sbjct: 65 ASSLQGSQVDGVFCVAGG 82 >3QVK-A nrPDB Length = 245 Score = 28.5 bits (62), Expect = 4.4, Method: Composition-based stats. Identities = 19/71 (26%), Positives = 25/71 (35%), Gaps = 2/71 (2%) Query: 138 VQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQMAEKLGAAAGFNYKKEDF 197 ++ I G G+ T A QLTR V G ++M E L A K D Sbjct: 170 LKEDGSGAIVLGSGGMATLAQQLTREL--RVPVIDGVSAAVKMVESLVALGLATSKHGDL 227 Query: 198 SEATLKFTKGA 208 + K G Sbjct: 228 AFPEKKALSGQ 238 >2C82-A nrPDB Length = 413 Score = 28.1 bits (61), Expect = 5.1, Method: Composition-based stats. Identities = 29/190 (15%), Positives = 58/190 (30%), Gaps = 30/190 (15%) Query: 144 VLIHAGLSGVGTAAIQL------------TRMAGAIPLVTAGSQK-----KLQMAEKLGA 186 V++ +GT A+Q+ GA + + +A++ A Sbjct: 15 VVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEHAA 74 Query: 187 AAG--FNYKKEDFSEATLKFTKGAGVNLILDC-IGGSYWEKNVNCLALDGRWVLY---GL 240 Y D + ++ T+ +++L+ +G + L R L L Sbjct: 75 QRVGDIPYHGSDAATRLVEQTE---ADVVLNALVGALGLRPTLAALKTGARLALANKESL 131 Query: 241 MGGGDING----PLFSKLLFKRGSLITSLLRSRDNKYKQMLVNAFTEQILPHFSTEGPQR 296 + GG + P + S + LR LV + +S + Sbjct: 132 VAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWSAADLEH 191 Query: 297 LLPVLDRIYP 306 + P +P Sbjct: 192 VTPEQAGAHP 201 >3ZV3-A nrPDB Length = 281 Score = 28.1 bits (61), Expect = 5.5, Method: Composition-based stats. Identities = 14/42 (33%), Positives = 20/42 (47%) Query: 141 GDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQMAE 182 G+ LI G SG+G A + GA V S ++L+ E Sbjct: 5 GEVALITGGASGLGRALVDRFVAEGARVAVLDKSAERLRELE 46 >4IIN-A nrPDB Length = 271 Score = 28.1 bits (61), Expect = 6.0, Method: Composition-based stats. Identities = 21/101 (20%), Positives = 32/101 (31%), Gaps = 9/101 (8%) Query: 141 GDYVLIHAGLSGVG-----TAAIQLTRMA-GAIPLVTAGSQKKLQMAEKLGAAAGFNY-- 192 G VLI G+G T A ++ K ++ EK AA + Sbjct: 29 GKNVLITGASKGIGAEIAKTLASMGLKVWINYRSNAEVADALKNELEEKGYKAAVIKFDA 88 Query: 193 -KKEDFSEATLKFTKGAGVNLILDCIGGSYWEKNVNCLALD 232 + DF EA + G L G +K + + Sbjct: 89 ASESDFIEAIQTIVQSDGGLSYLVNNAGVVRDKLAIKMKTE 129 >2YVG-A nrPDB Length = 408 Score = 28.1 bits (61), Expect = 6.0, Method: Composition-based stats. Identities = 14/60 (23%), Positives = 20/60 (33%), Gaps = 2/60 (3%) Query: 110 PEGLTLTQAAAIPEAWL-TAFQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIP 168 P L Q A +P L T + ++ +LI G +G R AG Sbjct: 113 PRALPTLQGATMPVHTLRTLEDARRIQAGLRPQSRLLIVGG-GVIGLELAATARTAGVHV 171 >6J0Z-C nrPDB Length = 491 Score = 28.1 bits (61), Expect = 6.1, Method: Composition-based stats. Identities = 10/47 (21%), Positives = 19/47 (40%) Query: 142 DYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQMAEKLGAAA 188 D ++ G G R+AG +V + ++ + LG +A Sbjct: 5 DSDVVVVGAGPTGLMLAGELRLAGVSVVVLDKLAEPIKESRALGFSA 51 >1W1U-A nrPDB Length = 557 Score = 28.1 bits (61), Expect = 6.2, Method: Composition-based stats. Identities = 23/103 (22%), Positives = 42/103 (40%), Gaps = 9/103 (8%) Query: 133 HLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQMAEKLGAAAGFNY 192 H G+++ G +VL AGL G+G A +AGA L Q ++ + + Sbjct: 160 HYGGSLK-GKWVL-TAGLGGMGGAQPLAATLAGACSLNIESQQSRIDFRLE---TRYVDE 214 Query: 193 KKEDFSEATLKFTK--GAGVNLILDCIGGSYWEKNVNCLALDG 233 + D +A ++ K G + + G + + + L G Sbjct: 215 QATDLDDALVRIAKYTAEGKAISIALHGNAA--EILPELVKRG 255 >4GBJ-A nrPDB Length = 297 Score = 28.1 bits (61), Expect = 6.3, Method: Composition-based stats. Identities = 26/153 (16%), Positives = 49/153 (32%), Gaps = 11/153 (7%) Query: 149 GLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQMAEKLGAAAGFNYKKEDFSEATLKFTKGA 208 GL +GT ++ AG +V + K + KLGA N A T G Sbjct: 12 GLGNLGTPIAEILLEAGYELVVWNRTASKAEPLTKLGATVVEN--------AIDAITPGG 63 Query: 209 GVNLILDCIGGSYWEKNVNCLALDGRWVLYGLMGGGDINGPLFSKLLFKRGSLITSLLRS 268 ++ + + + + L + G+ P S+ L + + Sbjct: 64 ---IVFSVLADDAAVEELFSMELVEKLGKDGVHVSMSTISPETSRQLAQVHEWYGAHYVG 120 Query: 269 RDNKYKQMLVNAFTEQILPHFSTEGPQRLLPVL 301 + V A I + +R+ P++ Sbjct: 121 APIFARPEAVRAKVGNICLSGNAGAKERIKPIV 153 >2EXX-A nrPDB Length = 306 Score = 27.7 bits (60), Expect = 6.6, Method: Composition-based stats. Identities = 10/62 (16%), Positives = 20/62 (32%), Gaps = 3/62 (4%) Query: 131 LLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQMAEKL---GAA 187 L G + V++ G G + + G + + + A++L GA Sbjct: 1 LYKKAGLMVDKKLVVVFGGTGAQGGSVARTLLEDGTFKVRVVTRNPRKKAAKELRLQGAE 60 Query: 188 AG 189 Sbjct: 61 VV 62 >5XA2-A nrPDB Length = 309 Score = 27.7 bits (60), Expect = 6.7, Method: Composition-based stats. Identities = 13/77 (16%), Positives = 24/77 (31%), Gaps = 4/77 (5%) Query: 133 HLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAG---SQKKLQMAEKLGAAAG 189 G ++ G +V + G A + G +T S ++ M + GA Sbjct: 56 EQSGKLKPGMHV-VEPTSGNTGIALAFVCAARGYKLTLTMPETMSIERRMMLKSFGADLV 114 Query: 190 FNYKKEDFSEATLKFTK 206 + A K + Sbjct: 115 LTPGADGMKGAISKAEE 131 >4BO1-A nrPDB Length = 269 Score = 27.7 bits (60), Expect = 6.7, Method: Composition-based stats. Identities = 17/71 (23%), Positives = 27/71 (38%), Gaps = 7/71 (9%) Query: 140 AGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGS---QKKLQMAEKL----GAAAGFNY 192 G L+ G+G A GA+ + TA S +K+ K GA + Sbjct: 26 QGKVALVTGASRGIGQAIALELGRLGAVVIGTATSASGAEKIAETLKANGVEGAGLVLDV 85 Query: 193 KKEDFSEATLK 203 ++ ATL+ Sbjct: 86 SSDESVAATLE 96 >4NBT-A nrPDB Length = 240 Score = 27.7 bits (60), Expect = 6.7, Method: Composition-based stats. Identities = 13/78 (16%), Positives = 18/78 (23%), Gaps = 14/78 (17%) Query: 140 AGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQMAEKLGAAAGFNYKKEDFSE 199 G +I G G+G A GA + Y + Sbjct: 5 EGKVAVITGGAKGLGQAIALAYAEEGAKVIAGDLGD--------------LTYSHPNVEG 50 Query: 200 ATLKFTKGAGVNLILDCI 217 L T GV + Sbjct: 51 MYLNVTDVTGVEKFYQSV 68 >4LZJ-A nrPDB Length = 303 Score = 27.7 bits (60), Expect = 7.1, Method: Composition-based stats. Identities = 17/82 (20%), Positives = 30/82 (36%), Gaps = 7/82 (8%) Query: 144 VLIHAGLSGVGTAAI---QLTRMAGAIPLVTAGSQKKLQMAEKLGAAAGF-NYKKEDFSE 199 VL+ SG I Q + GA+ + A S K +MAE A + Sbjct: 140 VLVGIAASGRTPYVIAGLQYAKSLGALTISIA-SNPKSEMAEI--ADIAIETIVGPEILT 196 Query: 200 ATLKFTKGAGVNLILDCIGGSY 221 + + G ++L+ + + Sbjct: 197 GSSRLKSGTAQKMVLNMLTTAS 218 >5VMT-A nrPDB Length = 342 Score = 27.3 bits (59), Expect = 8.3, Method: Composition-based stats. Identities = 24/132 (18%), Positives = 46/132 (34%), Gaps = 24/132 (18%) Query: 144 VLIHAGLSGVGTAAI-QLTRMAGAIPLVT---------------AGSQKKLQMAEKLGAA 187 V I+ G +G A+ Q+ + G +Q + Q +L Sbjct: 13 VAIN-GFGRIGRLALRQIEKAHGIEVAAVNDLTPAEMLLHLFKYDSTQGRFQGTAELKDD 71 Query: 188 AGFNYKKE-----DFSEATLKFTKGAGVNLILDCIG-GSYWEKNVNCLALDGRWVLYGLM 241 A +E + + L + GV+++L+C G + K + R V+ Sbjct: 72 AIVVNGREIKVFANPNPEELPW-GELGVDVVLECTGFFTNKTKAEAHIRAGARKVVISAP 130 Query: 242 GGGDINGPLFSK 253 GG D+ ++ Sbjct: 131 GGNDVKTVVYGV 142 >1YXM-A nrPDB Length = 303 Score = 27.3 bits (59), Expect = 8.4, Method: Composition-based stats. Identities = 9/49 (18%), Positives = 24/49 (48%) Query: 133 HLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQMA 181 +L + G ++ G +G+G A ++ G+ ++ + ++L+ A Sbjct: 10 YLAPGLLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSA 58 >1LU9-A nrPDB Length = 287 Score = 27.3 bits (59), Expect = 9.7, Method: Composition-based stats. Identities = 15/90 (16%), Positives = 28/90 (31%), Gaps = 9/90 (10%) Query: 132 LHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQMAEKLGAAAG-- 189 + G G ++ AG VG + L GA ++ K Q A A + Sbjct: 110 VKAAGGSVKGKKAVVLAGTGPVGMRSAALLAGEGAEVVLCGRKLDKAQAA----ADSVNK 165 Query: 190 ---FNYKKEDFSEATLKFTKGAGVNLILDC 216 N + ++ + G + + Sbjct: 166 RFKVNVTAAETADDASRAEAVKGAHFVFTA 195 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.311 0.134 0.337 Lambda K H 0.267 0.0408 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 12,291,594 Number of Sequences: 36641 Number of extensions: 519996 Number of successful extensions: 2642 Number of sequences better than 10.0: 266 Number of HSP's better than 10.0 without gapping: 223 Number of HSP's successfully gapped in prelim test: 134 Number of HSP's that attempted gapping in prelim test: 1895 Number of HSP's gapped (non-prelim): 401 length of query: 332 length of database: 10,336,785 effective HSP length: 97 effective length of query: 235 effective length of database: 6,782,608 effective search space: 1593912880 effective search space used: 1593912880 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 59 (27.3 bits)