BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q53079 (294 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 1Q5R-H nrPDB 579 e-166 1Q5Q-H nrPDB 446 e-126 2JAY-A nrPDB 317 5e-87 5LZP-A nrPDB 282 1e-76 3H4P-a nrPDB 75 3e-14 6HEC-1 nrPDB 75 5e-14 3IPM-H nrPDB 72 4e-13 6EPF-5 nrPDB 69 2e-12 5LN3-5 nrPDB 69 3e-12 3NZW-K nrPDB 62 4e-10 5L64-K nrPDB 62 4e-10 3UNB-K nrPDB 61 5e-10 5CZ8-K nrPDB 58 5e-09 6EPF-2 nrPDB 53 2e-07 6HUB-H nrPDB 51 5e-07 5L4G-8 nrPDB 51 6e-07 5FMG-L nrPDB 51 6e-07 3H4P-A nrPDB 51 6e-07 6AVO-A nrPDB 49 3e-06 5MPC-h nrPDB 47 1e-05 6AVO-C nrPDB 45 3e-05 3UNF-K nrPDB 44 6e-05 5FMG-N nrPDB 43 1e-04 5FGI-H nrPDB 42 2e-04 5L4G-U nrPDB 42 2e-04 6EPF-6 nrPDB 42 3e-04 3UNH-H nrPDB 41 6e-04 5GJQ-a nrPDB 40 0.001 5VFT-S nrPDB 40 0.001 5JI2-A nrPDB 40 0.001 5FMG-I nrPDB 40 0.001 6AVO-B nrPDB 39 0.002 6EPC-1 nrPDB 39 0.002 3TY6-A nrPDB 39 0.004 6HV7-H nrPDB 38 0.004 5LEZ-N nrPDB 38 0.006 2KU2-A nrPDB 38 0.006 5FMG-E nrPDB 37 0.011 3UNF-N nrPDB 37 0.014 5FMG-H nrPDB 36 0.017 6J30-C nrPDB 36 0.023 3UNE-I nrPDB 36 0.024 2Z3B-A nrPDB 35 0.035 4Y8P-I nrPDB 34 0.095 6GOP-M nrPDB 33 0.15 5FMG-C nrPDB 33 0.18 6HE5-A nrPDB 33 0.19 1OFH-G nrPDB 32 0.37 5DT9-A nrPDB 31 0.56 3NZW-L nrPDB 30 0.86 5GJQ-g nrPDB 30 0.88 5LF6-M nrPDB 30 1.1 5LE5-B nrPDB 30 1.3 5FGG-F nrPDB 30 1.6 6FVW-g nrPDB 30 1.8 3N5I-A nrPDB 30 1.8 4FZC-A nrPDB 29 2.2 2Z5C-C nrPDB 29 3.0 1VH3-A nrPDB 29 3.0 2YWH-A nrPDB 28 3.2 4HO7-A nrPDB 28 3.4 1G0U-D nrPDB 28 5.9 6EPE-7 nrPDB 28 6.0 >1Q5R-H nrPDB Length = 294 Score = 579 bits (1493), Expect = e-166, Method: Compositional matrix adjust. Identities = 293/294 (99%), Positives = 293/294 (99%) Query: 1 MTADRPALRTGDRDTRLSFGSNLSSFTDYLRGHAPELLPENRIGHRSHSTRGGDGMESGD 60 MTADRPALRTGDRDTRLSFGSNLSSFTDYLRGHAPELLPENRIGHRSHSTRGGDGMESGD Sbjct: 1 MTADRPALRTGDRDTRLSFGSNLSSFTDYLRGHAPELLPENRIGHRSHSTRGGDGMESGD 60 Query: 61 LAPHGTTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAGTAGIAIEL 120 LAPHGTTIVALTYKGGVLLAGDRRATQGNLIASRDVE VYVTDEYSAAGIAGTAGIAIEL Sbjct: 61 LAPHGTTIVALTYKGGVLLAGDRRATQGNLIASRDVEAVYVTDEYSAAGIAGTAGIAIEL 120 Query: 121 VRLFAVELEHYEKIEGVPLTFDGKANRLASMVRGNLGAAMQGLAVVPLLVGYDLDADDES 180 VRLFAVELEHYEKIEGVPLTFDGKANRLASMVRGNLGAAMQGLAVVPLLVGYDLDADDES Sbjct: 121 VRLFAVELEHYEKIEGVPLTFDGKANRLASMVRGNLGAAMQGLAVVPLLVGYDLDADDES 180 Query: 181 RAGRIVSYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDSDEETALRAAIESLYDAA 240 RAGRIVSYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDSDEETALRAAIESLYDAA Sbjct: 181 RAGRIVSYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDSDEETALRAAIESLYDAA 240 Query: 241 DDDSATGGPDLTRGIYPTAVTITQAGAVHVSEETTSELARRIVAERTEQGGSAR 294 DDDSATGGPDLTRGIYPTAVTITQAGAVHVSEETTSELARRIVAERTEQGGSAR Sbjct: 241 DDDSATGGPDLTRGIYPTAVTITQAGAVHVSEETTSELARRIVAERTEQGGSAR 294 >1Q5Q-H nrPDB Length = 235 Score = 446 bits (1148), Expect = e-126, Method: Compositional matrix adjust. Identities = 229/229 (100%), Positives = 229/229 (100%) Query: 66 TTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAGTAGIAIELVRLFA 125 TTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAGTAGIAIELVRLFA Sbjct: 1 TTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAGTAGIAIELVRLFA 60 Query: 126 VELEHYEKIEGVPLTFDGKANRLASMVRGNLGAAMQGLAVVPLLVGYDLDADDESRAGRI 185 VELEHYEKIEGVPLTFDGKANRLASMVRGNLGAAMQGLAVVPLLVGYDLDADDESRAGRI Sbjct: 61 VELEHYEKIEGVPLTFDGKANRLASMVRGNLGAAMQGLAVVPLLVGYDLDADDESRAGRI 120 Query: 186 VSYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDSDEETALRAAIESLYDAADDDSA 245 VSYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDSDEETALRAAIESLYDAADDDSA Sbjct: 121 VSYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDSDEETALRAAIESLYDAADDDSA 180 Query: 246 TGGPDLTRGIYPTAVTITQAGAVHVSEETTSELARRIVAERTEQGGSAR 294 TGGPDLTRGIYPTAVTITQAGAVHVSEETTSELARRIVAERTEQGGSAR Sbjct: 181 TGGPDLTRGIYPTAVTITQAGAVHVSEETTSELARRIVAERTEQGGSAR 229 >2JAY-A nrPDB Length = 291 Score = 317 bits (811), Expect = 5e-87, Method: Compositional matrix adjust. Identities = 171/267 (64%), Positives = 201/267 (75%), Gaps = 9/267 (3%) Query: 22 NLSSFTDYLRGHAPELLPENRIGHRSHSTRGGDGMESGDLA-PHGTTIVALTYKGGVLLA 80 +LSSFTD+LR APELLP S GG + GD PHGTTIVAL Y GGV++A Sbjct: 21 DLSSFTDFLRRQAPELLPA--------SISGGAPLAGGDAQLPHGTTIVALKYPGGVVMA 72 Query: 81 GDRRATQGNLIASRDVEKVYVTDEYSAAGIAGTAGIAIELVRLFAVELEHYEKIEGVPLT 140 GDRR+TQGN+I+ RDV KVY+TD+Y+A GIAGTA +A+E RL+AVELEHYEK+EGVPLT Sbjct: 73 GDRRSTQGNMISGRDVRKVYITDDYTATGIAGTAAVAVEFARLYAVELEHYEKLEGVPLT 132 Query: 141 FDGKANRLASMVRGNLGAAMQGLAVVPLLVGYDLDADDESRAGRIVSYDVVGGRYEERAG 200 F GK NRLA MVRGNL AAMQGL +PLL GYD+ A D AGRIVS+D GG E G Sbjct: 133 FAGKINRLAIMVRGNLAAAMQGLLALPLLAGYDIHASDPQSAGRIVSFDAAGGWNIEEEG 192 Query: 201 YHAVGSGSLFAKSALKKIYSPDSDEETALRAAIESLYDAADDDSATGGPDLTRGIYPTAV 260 Y AVGSGSLFAKS++KK+YS +D ++ LR A+E+LYDAADDDSATGGPDL RGI+PTAV Sbjct: 193 YQAVGSGSLFAKSSMKKLYSQVTDGDSGLRVAVEALYDAADDDSATGGPDLVRGIFPTAV 252 Query: 261 TITQAGAVHVSEETTSELARRIVAERT 287 I GAV V E +ELAR I+ R+ Sbjct: 253 IIDADGAVDVPESRIAELARAIIESRS 279 >5LZP-A nrPDB Length = 242 Score = 282 bits (721), Expect = 1e-76, Method: Compositional matrix adjust. Identities = 148/221 (66%), Positives = 175/221 (79%) Query: 67 TIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAGTAGIAIELVRLFAV 126 TIVAL Y GGV++AGDRR+TQGN+I+ RDV KVY+TD+Y+A GIAGTA +A+E RL+AV Sbjct: 2 TIVALKYPGGVVMAGDRRSTQGNMISGRDVRKVYITDDYTATGIAGTAAVAVEFARLYAV 61 Query: 127 ELEHYEKIEGVPLTFDGKANRLASMVRGNLGAAMQGLAVVPLLVGYDLDADDESRAGRIV 186 ELEHYEK+EGVPLTF GK NRLA MVRGNL AAMQGL +PLL GYD+ A D AGRIV Sbjct: 62 ELEHYEKLEGVPLTFAGKINRLAIMVRGNLAAAMQGLLALPLLAGYDIHASDPQSAGRIV 121 Query: 187 SYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDSDEETALRAAIESLYDAADDDSAT 246 S+D GG E GY AVGSGSLFAKS++KK+YS +D ++ LR A+E+LYDAADDDSAT Sbjct: 122 SFDAAGGWNIEEEGYQAVGSGSLFAKSSMKKLYSQVTDGDSGLRVAVEALYDAADDDSAT 181 Query: 247 GGPDLTRGIYPTAVTITQAGAVHVSEETTSELARRIVAERT 287 GGPDL RGI+PTAV I GAV V E +ELAR I+ R+ Sbjct: 182 GGPDLVRGIFPTAVIIDADGAVDVPESRIAELARAIIESRS 222 >3H4P-a nrPDB Length = 219 Score = 75.1 bits (183), Expect = 3e-14, Method: Compositional matrix adjust. Identities = 58/182 (31%), Positives = 92/182 (50%), Gaps = 9/182 (4%) Query: 66 TTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAGTAGIAIELVRLFA 125 TT V L V+LA D+RA+ GNL+A ++ +K+Y D+Y A IAG+ G A +VRL Sbjct: 2 TTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIVRLLI 61 Query: 126 VELEHYEKIEGVPLTFDGKANRLASMVRGNLGAAMQGLAVVPLLVGYDLDADDESRAGRI 185 E + Y+ G + A L++++ + M ++ GYDL ++ Sbjct: 62 AEAKLYKMRTGRNIPPLACATLLSNILH---SSRMFPFLTQIIIGGYDL-----LEGAKL 113 Query: 186 VSYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDSDEETALRAAIESLYDAADDDSA 245 S D +GG EE+ + A GSGS A L+ Y D E ++ A+ +L A + D+ Sbjct: 114 FSLDPLGGMNEEKT-FTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERDTF 172 Query: 246 TG 247 +G Sbjct: 173 SG 174 >6HEC-1 nrPDB Length = 202 Score = 74.7 bits (182), Expect = 5e-14, Method: Compositional matrix adjust. Identities = 64/190 (33%), Positives = 100/190 (52%), Gaps = 13/190 (6%) Query: 66 TTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAGTAGIAIELVRLFA 125 TT V L K GV++A ++RAT GN IAS+ +K+Y + A AG+ G A L R+ Sbjct: 1 TTTVGLVCKDGVVMATEKRATMGNFIASKAAKKIYQIADRMAMTTAGSVGDAQFLARIIK 60 Query: 126 VELEHYE-KIEGVPLTFDGKANRLASMVRGNLGAAMQGLAVVPLLVGYDLDADDESRAGR 184 +E YE + E P +A++ L + +V LL+G +D++ +S Sbjct: 61 IEANLYEIRRERKP-----TVRAIATLTSNLLNSYRYFPYLVQLLIG-GIDSEGKS---- 110 Query: 185 IVSYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDSDEETALRAAIESLYDAADDDS 244 I S D +GG EE+ A GSGSL A L+ ++P+ + A+ A+ ++Y A DS Sbjct: 111 IYSIDPIGGAIEEK-DIVATGSGSLTAYGVLEDRFTPEIGVDEAVELAVRAIYSAMKRDS 169 Query: 245 ATG-GPDLTR 253 A+G G D+ + Sbjct: 170 ASGDGIDVVK 179 >3IPM-H nrPDB Length = 217 Score = 71.6 bits (174), Expect = 4e-13, Method: Compositional matrix adjust. Identities = 61/184 (33%), Positives = 86/184 (46%), Gaps = 12/184 (6%) Query: 65 GTTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAGTAGIAIELVRLF 124 GTT V +T K V++A +RR T N I ++ +K++ D Y+ IAG G A LVR Sbjct: 8 GTTTVGITLKDAVIMATERRVTMENFIMHKNGKKLFQIDTYTGMTIAGLVGDAQVLVRYM 67 Query: 125 AVELEHYEKIEGVPLTFDGKANRLASMVRGNLGAAMQGLAVVPLLVGYDLDADDESRAGR 184 ELE Y V + + A L++M L +V LLVG +D A Sbjct: 68 KAELELYRLQRRVNMPIEAVATLLSNM----LNQVKYMPYMVQLLVG-GIDT-----APH 117 Query: 185 IVSYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDSDEETALRAAIESLYDAADDDS 244 + S D GG E+ Y + GSGS F L+ YS + + I ++ A DS Sbjct: 118 VFSIDAAGGSVEDI--YASTGSGSPFVYGVLESQYSEKMTVDEGVDLVIRAISAAKQRDS 175 Query: 245 ATGG 248 A+GG Sbjct: 176 ASGG 179 >6EPF-5 nrPDB Length = 263 Score = 69.3 bits (168), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 59/185 (31%), Positives = 88/185 (47%), Gaps = 11/185 (5%) Query: 64 HGTTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAGTAGIAIELVRL 123 HGTT +A ++ GV++A D RAT G IAS+ V+KV + Y +AG A RL Sbjct: 58 HGTTTLAFKFQHGVIVAADSRATAGPYIASQTVKKVIEINPYLLGTMAGGAADCSFWERL 117 Query: 124 FAVELEHYEKIEGVPLTFDGKANRLASMVRGNLGAAMQGLAVVPLLVGYDLDADDESRAG 183 A + YE ++ + LA+MV G GL++ ++ G+D R Sbjct: 118 LARQCRIYELRNKERISVAAASKLLANMVYQYKG---MGLSMGTMICGWD------KRGP 168 Query: 184 RIVSYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDSDEETALRAAIESLYDAADDD 243 + D G R A +VGSGS++A + + YS D E A A ++Y A D Sbjct: 169 GLYYVDSEGNRISGTA--FSVGSGSVYAFGVMDRGYSYDLQVEEAYDLARRAIYQATYRD 226 Query: 244 SATGG 248 + +GG Sbjct: 227 AYSGG 231 >5LN3-5 nrPDB Length = 263 Score = 68.6 bits (166), Expect = 3e-12, Method: Compositional matrix adjust. Identities = 58/185 (31%), Positives = 88/185 (47%), Gaps = 11/185 (5%) Query: 64 HGTTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAGTAGIAIELVRL 123 HGTT +A ++ GV++A D RAT G IAS+ V+KV + Y +AG A RL Sbjct: 58 HGTTTLAFKFRHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAADCSFWERL 117 Query: 124 FAVELEHYEKIEGVPLTFDGKANRLASMVRGNLGAAMQGLAVVPLLVGYDLDADDESRAG 183 A + YE ++ + LA+MV G GL++ ++ G+D R Sbjct: 118 LARQCRIYELRNKERISVAAASKLLANMVYQYKG---MGLSMGTMICGWD------KRGP 168 Query: 184 RIVSYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDSDEETALRAAIESLYDAADDD 243 + D G R +VGSGS++A + + YS D + E A A ++Y A D Sbjct: 169 GLYYVDSEGNRIS--GATFSVGSGSVYAYGVMDRGYSYDLEVEQAYDLARRAIYQATYRD 226 Query: 244 SATGG 248 + +GG Sbjct: 227 AYSGG 231 >3NZW-K nrPDB Length = 287 Score = 61.6 bits (148), Expect = 4e-10, Method: Compositional matrix adjust. Identities = 61/223 (27%), Positives = 99/223 (44%), Gaps = 19/223 (8%) Query: 64 HGTTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAGTAGIAIELVRL 123 HGTT +A ++GG+++A D RAT GN +AS+ V+KV + + +AG A Sbjct: 74 HGTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWETW 133 Query: 124 FAVELEHYEKIEGVPLTFDGKANRLASMVRGNLGAAMQGLAVVPLLVGYDLDADDESRAG 183 + +E E ++ + L+++V GA GL++ ++ GY + G Sbjct: 134 LGSQCRLHELREKERISVAAASKILSNLVYQYKGA---GLSMGTMICGY------TRKEG 184 Query: 184 RIVSY-DVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDSDEETALRAAIESLYDAADD 242 + Y D G R + VGSG FA L Y D E AL S+ AA Sbjct: 185 PTIYYVDSDGTRL--KGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHR 242 Query: 243 DSATGGPDLTRGIYPTAVTITQAGAVHVSEETTSELARRIVAE 285 D+ +GG + +Y +T+ G ++ EL ++ E Sbjct: 243 DAYSGG---SVNLY----HVTEDGWIYHGNHDVGELFWKVKEE 278 >5L64-K nrPDB Length = 211 Score = 61.6 bits (148), Expect = 4e-10, Method: Compositional matrix adjust. Identities = 62/220 (28%), Positives = 94/220 (42%), Gaps = 18/220 (8%) Query: 66 TTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAGTAGIAIELVRLFA 125 TT +A ++ GV++A D RAT G IAS+ V+KV + Y +AG A RL A Sbjct: 1 TTTLAFKFRHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAADCSFWERLLA 60 Query: 126 VELEHYEKIEGVPLTFDGKANRLASMVRGNLGAAMQGLAVVPLLVGYDLDADDESRAGRI 185 + YE ++ + LA+MV G GL++ ++ G+D R + Sbjct: 61 RQCRIYELRNKERISVAAASKLLANMVYQYKG---MGLSMGTMICGWD------KRGPGL 111 Query: 186 VSYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDSDEETALRAAIESLYDAADDDSA 245 D G R +VGSGS++A L Y D E AL S+ AA D+ Sbjct: 112 YYVDSEGNRIS--GATFSVGSGSVYAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAY 169 Query: 246 TGGPDLTRGIYPTAVTITQAGAVHVSEETTSELARRIVAE 285 +GG +T+ G ++ EL ++ E Sbjct: 170 SGGS-------VNLYHVTEDGWIYHGNHDVGELFWKVKEE 202 >3UNB-K nrPDB Length = 205 Score = 61.2 bits (147), Expect = 5e-10, Method: Compositional matrix adjust. Identities = 61/213 (28%), Positives = 95/213 (44%), Gaps = 18/213 (8%) Query: 66 TTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAGTAGIAIELVRLFA 125 TT +A + GV++A D RAT G IAS+ V+KV + Y +AG A RL A Sbjct: 1 TTTLAFKFLHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAADCSFWERLLA 60 Query: 126 VELEHYEKIEGVPLTFDGKANRLASMVRGNLGAAMQGLAVVPLLVGYDLDADDESRAGRI 185 + YE ++ + LA+MV G GL++ ++ G+D R + Sbjct: 61 RQCRIYELRNKERISVAAASKLLANMVYQYKG---MGLSMGTMICGWD------KRGPGL 111 Query: 186 VSYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDSDEETALRAAIESLYDAADDDSA 245 D G R A +VGSGS++A + + YS D E A A ++Y A D+ Sbjct: 112 YYVDSEGNRISGTA--FSVGSGSVYAYGVMDRGYSYDLKVEEAYDLARRAIYQATYRDAY 169 Query: 246 TGGPDLTRGIYPTAVTITQAGAVHVSEETTSEL 278 +GG + + G + VS + ++L Sbjct: 170 SGGA-------VNLYHVREDGWIRVSSDNVADL 195 >5CZ8-K nrPDB Length = 221 Score = 57.8 bits (138), Expect = 5e-09, Method: Compositional matrix adjust. Identities = 60/223 (26%), Positives = 98/223 (43%), Gaps = 19/223 (8%) Query: 64 HGTTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAGTAGIAIELVRL 123 HGTT +A ++GG+++A D RAT GN +AS+ V+ V + + +AG A Sbjct: 8 HGTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKAVIEINPFLLGTMAGGAADCQFWETW 67 Query: 124 FAVELEHYEKIEGVPLTFDGKANRLASMVRGNLGAAMQGLAVVPLLVGYDLDADDESRAG 183 + +E E ++ + L+++V GA GL++ ++ GY + G Sbjct: 68 LGSQCRLHELREKERISVAAASKILSNLVYQYKGA---GLSMGTMICGY------TRKEG 118 Query: 184 RIVSY-DVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDSDEETALRAAIESLYDAADD 242 + Y D G R + VGSG FA L Y D E AL S+ AA Sbjct: 119 PTIYYVDSDGTRL--KGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHR 176 Query: 243 DSATGGPDLTRGIYPTAVTITQAGAVHVSEETTSELARRIVAE 285 D+ +GG + +Y +T+ G ++ EL ++ E Sbjct: 177 DAYSGG---SVNLYH----VTEDGWIYHGNHDVGELFWKVKEE 212 >6EPF-2 nrPDB Length = 277 Score = 52.8 bits (125), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 50/188 (26%), Positives = 84/188 (44%), Gaps = 22/188 (11%) Query: 65 GTTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAGTAGIAIELVRLF 124 GTTI + YK G++L D RAT+G ++A ++ K++ AGTA +L Sbjct: 43 GTTIAGVVYKDGIVLGADTRATEGMVVADKNCSKIHFISPNIYCCGAGTAADTDMTTQLI 102 Query: 125 AVELEHYEKIEG-VPLTFDGKANRLASMV----RGNLGAAMQGLAVVPLLVGYDLDADDE 179 + LE + G +P ANR+ + +G +GAA+ +L G D+ Sbjct: 103 SSNLELHSLTTGRLPRVV--TANRMLKQMLFRYQGYIGAAL-------VLGGVDVTGPH- 152 Query: 180 SRAGRIVSYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDSDEETALRAAIESLYDA 239 Y + ++ Y +GSGSL A + + + PD +EE A + E++ Sbjct: 153 -------LYSIYPHGSTDKLPYVTMGSGSLAAMAVFEDKFRPDMEEEEAKKLVSEAIAAG 205 Query: 240 ADDDSATG 247 +D +G Sbjct: 206 IFNDLGSG 213 >6HUB-H nrPDB Length = 234 Score = 51.2 bits (121), Expect = 5e-07, Method: Compositional matrix adjust. Identities = 50/188 (26%), Positives = 83/188 (44%), Gaps = 22/188 (11%) Query: 66 TTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAGTAGIAIELVRLFA 125 TTI + YK G++L D RAT+G ++A ++ K++ AGTA +L + Sbjct: 1 TTIAGVVYKDGIVLGADTRATEGMVVADKNCSKIHFISPNIYCCGAGTAADTDMTTQLIS 60 Query: 126 VELEHYEKIEG-VPLTFDGKANRLASMV----RGNLGAAMQGLAVVPLLVGYDLDADDES 180 LE + G +P ANR+ + +G +GAA+ +L G D+ Sbjct: 61 SNLELHSLSTGRLPRVV--TANRMLKQMLFRYQGYIGAAL-------VLGGVDVTGPH-- 109 Query: 181 RAGRIVSYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDSDEETALRAAIESLYDAA 240 Y + ++ Y +GSGSL A + + + PD +EE A E++ Sbjct: 110 ------LYSIYPHGSTDKLPYVTMGSGSLAAMAVFEDKFRPDMEEEEAKNLVSEAIAAGI 163 Query: 241 DDDSATGG 248 +D +GG Sbjct: 164 FNDLGSGG 171 >5L4G-8 nrPDB Length = 277 Score = 51.2 bits (121), Expect = 6e-07, Method: Compositional matrix adjust. Identities = 50/188 (26%), Positives = 83/188 (44%), Gaps = 22/188 (11%) Query: 65 GTTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAGTAGIAIELVRLF 124 GTTI + YK G++L D RAT+G ++A ++ K++ AGTA +L Sbjct: 43 GTTIAGVVYKDGIVLGADTRATEGMVVADKNCSKIHFISPNIYCCGAGTAADTDMTTQLI 102 Query: 125 AVELEHYEKIEG-VPLTFDGKANRLASMV----RGNLGAAMQGLAVVPLLVGYDLDADDE 179 + LE + G +P ANR+ + +G +GAA+ +L G D+ Sbjct: 103 SSNLELHSLSTGRLPRVV--TANRMLKQMLFRYQGYIGAAL-------VLGGVDVTGPH- 152 Query: 180 SRAGRIVSYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDSDEETALRAAIESLYDA 239 Y + ++ Y +GSGSL A + + + PD +EE A E++ Sbjct: 153 -------LYSIYPHGSTDKLPYVTMGSGSLAAMAVFEDKFRPDMEEEEAKNLVSEAIAAG 205 Query: 240 ADDDSATG 247 +D +G Sbjct: 206 IFNDLGSG 213 >5FMG-L nrPDB Length = 211 Score = 50.8 bits (120), Expect = 6e-07, Method: Compositional matrix adjust. Identities = 53/194 (27%), Positives = 91/194 (46%), Gaps = 31/194 (15%) Query: 66 TTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAGTAGIAI------- 118 TT +A +K G+++A D RA+ G+ I+S++VEK+ ++ +AG A + Sbjct: 1 TTTLAFKFKDGIIVAVDSRASMGSFISSQNVEKIIEINKNILGTMAGGAADCLYWEKYLG 60 Query: 119 ELVRLFAVELEHYEKIEGVPLTFDGKANRLASMVRGNLGAAMQ--GLAVVPLLVGYDLDA 176 ++++++ EL + EKI + R AS + N+ + GL +L GYD Sbjct: 61 KIIKIY--ELRNNEKI----------SVRAASTILSNILYQYKGYGLCCGIILSGYD--- 105 Query: 177 DDESRAGRIVSY-DVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDSDEETALRAAIES 235 G + Y D G + E + GSGS +A S L Y + + + A+ A + Sbjct: 106 ----HTGFNMFYVDDSGKKVE--GNLFSCGSGSTYAYSILDSAYDYNLNLDQAVELARNA 159 Query: 236 LYDAADDDSATGGP 249 +Y A D +GG Sbjct: 160 IYHATFRDGGSGGK 173 >3H4P-A nrPDB Length = 264 Score = 50.8 bits (120), Expect = 6e-07, Method: Compositional matrix adjust. Identities = 52/179 (29%), Positives = 82/179 (45%), Gaps = 8/179 (4%) Query: 64 HGTTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAGTAGIAIELVRL 123 GTT + + K GV+LA DRR T L+ R +EK++ D++ AA +G A L+ Sbjct: 37 RGTTAIGIACKDGVVLAVDRRIT-SKLVKIRSIEKIFQIDDHVAAATSGLVADARVLIDR 95 Query: 124 FAVELEHYEKIEGVPLTFDGKANRLASMVRGNLGAAMQGLAVVPLLVGYDLDADDESRAG 183 +E + Y G ++ + A ++ + + A Q V P V + D++ A Sbjct: 96 ARLEAQIYRLTYGEEISIEMLAKKICDIKQ----AYTQHGGVRPFGVSLLIAGIDKNEA- 150 Query: 184 RIVSYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDSDEETALRAAIESLYDAADD 242 R+ D G E +A A+GSG L+K Y D + L AI +L A +D Sbjct: 151 RLFETDPSGALIEYKAT--AIGSGRPVVMELLEKEYRDDITLDEGLELAITALTKANED 207 >6AVO-A nrPDB Length = 199 Score = 48.5 bits (114), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 56/205 (27%), Positives = 92/205 (44%), Gaps = 21/205 (10%) Query: 66 TTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAGTAGIAIELVRLFA 125 TTI+A+ + GGV++ D R + G + +R +K+ E ++G+A A + + A Sbjct: 1 TTIMAVEFDGGVVMGSDSRVSAGEAVVNRVFDKLSPLHERIYCALSGSAADAQAVADMAA 60 Query: 126 VELE-HYEKIEGVPLTFDGKANRLASMVRGNLGAAMQGLAVVPLLVGYDLDADDESRAGR 184 +LE H ++E PL A++VR + L+ ++ G+ D+ G+ Sbjct: 61 YQLELHGIELEEPPLVLAA-----ANVVRNISYKYREDLSAHLMVAGW-----DQREGGQ 110 Query: 185 IVSYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDSDEETALRAAIESLYDAADDDS 244 + Y +GG R + GSGS F + Y P E R +++ A D Sbjct: 111 V--YGTLGGML-TRQPFAIGGSGSTFIYGYVDAAYKPGMSPEECRRFTTDAIALAMSRDG 167 Query: 245 ATGGPDLTRGIYPTAVTITQAGAVH 269 ++GG IY VTIT AG H Sbjct: 168 SSGGV-----IY--LVTITAAGVDH 185 >5MPC-h nrPDB Length = 215 Score = 47.0 bits (110), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 48/184 (26%), Positives = 77/184 (41%), Gaps = 12/184 (6%) Query: 65 GTTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAGTAGIAIELVRLF 124 GT+I+A+T+K GV+L D R T G IA+R +K+ + +G+A + + Sbjct: 19 GTSIMAVTFKDGVILGADSRTTTGAYIANRVTDKLTRVHDKIWCCRSGSAADTQAIADIV 78 Query: 125 AVELEHYEKIEGVPLTFDGKANRLASMVRGNLGAAMQGLAVVPLLVGYDLDADDESRAGR 184 LE Y G P T + A+ + N G+ ++ GY D+ G Sbjct: 79 QYHLELYTSQYGTPST-ETAASVFKELCYENKDNLTAGI----IVAGY-----DDKNKGE 128 Query: 185 IVSYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDSDEETALRAAIESLYDAADDDS 244 + Y + G + Y GSGS F K + + +E + SL A D Sbjct: 129 V--YTIPLGGSVHKLPYAIAGSGSTFIYGYCDKNFRENMSKEETVDFIKHSLSQAIKWDG 186 Query: 245 ATGG 248 ++GG Sbjct: 187 SSGG 190 >6AVO-C nrPDB Length = 204 Score = 45.4 bits (106), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 48/184 (26%), Positives = 80/184 (43%), Gaps = 13/184 (7%) Query: 66 TTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAGTAGIAIELVRLFA 125 TT +A ++ GV+ A D RA+ G+ I++ V KV + Y ++G A RL A Sbjct: 1 TTTLAFKFQHGVIAAVDSRASAGSYISALRVNKVIEINPYLLGTMSGCAADCQYWERLLA 60 Query: 126 VELEHYEKIEGVPLTFDGKANRLASMVRGNLGAAMQGLAVVPLLVGYDLDADDESRAGRI 185 E Y G ++ + L++M+ G GL++ ++ G+D + G Sbjct: 61 KECRLYYLRNGERISVSAASKLLSNMMCQYRG---MGLSMGSMICGWD-------KKGPG 110 Query: 186 VSY-DVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDSDEETALRAAIESLYDAADDDS 244 + Y D G R + GSG+ +A + Y P+ E A ++ A DS Sbjct: 111 LYYVDEHGTRLS--GNMFSTGSGNTYAYGVMDSGYRPNLSPEEAYDLGRRAIAYATHRDS 168 Query: 245 ATGG 248 +GG Sbjct: 169 YSGG 172 >3UNF-K nrPDB Length = 204 Score = 44.3 bits (103), Expect = 6e-05, Method: Compositional matrix adjust. Identities = 31/108 (28%), Positives = 53/108 (49%), Gaps = 3/108 (2%) Query: 66 TTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAGTAGIAIELVRLFA 125 TT +A ++ GV++A D RAT G+ I+S + KV + Y ++G A RL A Sbjct: 1 TTTLAFKFQHGVIVAVDSRATAGSYISSLRMNKVIEINPYLLGTMSGCAADCQYWERLLA 60 Query: 126 VELEHYEKIEGVPLTFDGKANRLASMVRGNLGAAMQGLAVVPLLVGYD 173 E Y G ++ + L++M+ G GL++ ++ G+D Sbjct: 61 KECRLYYLRNGERISVSAASKLLSNMMLQYRG---MGLSMGSMICGWD 105 >5FMG-N nrPDB Length = 265 Score = 43.1 bits (100), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 15/48 (31%), Positives = 33/48 (68%) Query: 65 GTTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAG 112 GT+++A+ YK G+++A DR+A+ G+ ++VE+++ + + G +G Sbjct: 9 GTSVIAIKYKHGIMIAADRKASYGSYAKFQNVERIFKINNKTVMGFSG 56 >5FGI-H nrPDB Length = 244 Score = 42.4 bits (98), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 46/188 (24%), Positives = 87/188 (46%), Gaps = 22/188 (11%) Query: 65 GTTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVY-VTDEYSAAGIAGTAGIAIELVRL 123 G TIV + + GV++A D R+TQG ++A ++ K++ ++ + AG AGTA + +L Sbjct: 12 GATIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAG-AGTAADTEAVTQL 70 Query: 124 FAVELEHYEKIEGVPLTFDGKANRLAS---MVRGNLGAAMQGLAVVPLLVGYDLDADDES 180 +E + + + R+ S M++ +L + ++ G D Sbjct: 71 IGSNIELHS-------LYTSREPRVVSALQMLKQHLFKYQGHIGAYLIVAGVDPTGSHLF 123 Query: 181 RAGRIVSYDVVGGRYEERAGYH-AVGSGSLFAKSALKKIYSPDSDEETALRAAIESLYDA 239 S DV GY+ ++GSGSL A + L+ + D +E A++ A +++ Sbjct: 124 SIHAHGSTDV---------GYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAG 174 Query: 240 ADDDSATG 247 +D +G Sbjct: 175 IWNDLGSG 182 >5L4G-U nrPDB Length = 241 Score = 42.4 bits (98), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 41/177 (23%), Positives = 71/177 (40%), Gaps = 10/177 (5%) Query: 39 PENRIGHRSHSTRGGDGMESGDLAPHGTTIVALTYKGGVLLAGDRRATQGNLIASRDVEK 98 P +G H G + +G TI+A+ + ++A D R ++G I +RD K Sbjct: 11 PGRDLGMEPHRAAGPLQLRFSPYVFNGGTILAIAGEDFAIVASDTRLSEGFSIHTRDSPK 70 Query: 99 VYVTDEYSAAGIAGTAGIAIELVRLFAVELEHYEKIEGVPLTFDGKANRLASMVRGNLGA 158 Y + + G +G G + L ++ L+ Y+ +T A L++++ Sbjct: 71 CYKLTDKTVIGCSGFHGDCLTLTKIIEARLKMYKHSNNKAMTTGAIAAMLSTILYSR--- 127 Query: 159 AMQGLAVVPLLVGYDLDADDESRAGRIVSYDVVGGRYEERAGYHAVGSGSLFAKSAL 215 P V + DE G + S+D VG +R + A GS S + L Sbjct: 128 -----RFFPYYVYNIIGGLDEEGKGAVYSFDPVGSY--QRDSFKAGGSASAMLQPLL 177 >6EPF-6 nrPDB Length = 240 Score = 42.0 bits (97), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 38/160 (23%), Positives = 68/160 (42%), Gaps = 10/160 (6%) Query: 56 MESGDLAPHGTTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAGTAG 115 M A +G T++A+ + ++A D R ++G I +RD K Y + + G +G G Sbjct: 27 MRFSPYAFNGGTVLAIAGEDFSIVASDTRLSEGFSIHTRDSPKCYKLTDKTVIGCSGFHG 86 Query: 116 IAIELVRLFAVELEHYEKIEGVPLTFDGKANRLASMVRGNLGAAMQGLAVVPLLVGYDLD 175 + L ++ L+ Y+ +T A L++++ P V ++ Sbjct: 87 DCLTLTKIIEARLKMYKHSNNKAMTTGAIAAMLSTILYSR--------RFFPYYVYNIIE 138 Query: 176 ADDESRAGRIVSYDVVGGRYEERAGYHAVGSGSLFAKSAL 215 DE G + S+D VG +R + A GS S + L Sbjct: 139 GLDEEGKGAVYSFDPVGSY--QRDSFKAGGSASAMLQPLL 176 >3UNH-H nrPDB Length = 234 Score = 41.2 bits (95), Expect = 6e-04, Method: Compositional matrix adjust. Identities = 47/194 (24%), Positives = 84/194 (43%), Gaps = 34/194 (17%) Query: 66 TTIVALTYKGGVLLAGDRRATQGNLIASRDVEKV-YVTDEYSAAGIAGTAGIAIELVRLF 124 TTI L ++ GV+L D RAT +++A + EK+ ++ + G AG A R+ Sbjct: 1 TTIAGLVFRDGVILGADTRATNDSVVADKSCEKIHFIAPKIYCCG-AGVAADTEMTTRMA 59 Query: 125 AVELEHYEKIEGVPLTFDGKANRLASMVR----------GNLGAAMQGLAVVPLLVGYDL 174 A ++E + G+ R+A++ R G++GA++ ++ G DL Sbjct: 60 ASKMELHA-------LSTGREPRVATVTRILRQTLFRYQGHVGASL-------VVGGVDL 105 Query: 175 DADDESRAGRIVSYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDSDEETALRAAIE 234 + Y+V R + A+GSG A + L+ + P+ E A +E Sbjct: 106 NGPQ--------LYEVHPHGSYSRLPFTALGSGQGAAVALLEDRFQPNMTLEAAQELLVE 157 Query: 235 SLYDAADDDSATGG 248 ++ D +GG Sbjct: 158 AITAGILSDLGSGG 171 >5GJQ-a nrPDB Length = 239 Score = 40.0 bits (92), Expect = 0.001, Method: Compositional matrix adjust. Identities = 47/191 (24%), Positives = 76/191 (39%), Gaps = 25/191 (13%) Query: 65 GTTIVALTYKGGVLLAGDRRATQGNLIASRDVEK-------VYVTDEYSAAGIAGTAGIA 117 GTTI+A+ + GGV+L D R T G+ IA+R +K ++ SAA A Sbjct: 34 GTTIMAVQFDGGVVLGADSRTTTGSYIANRVTDKLTPIHDRIFCCRSGSAADTQAVADAV 93 Query: 118 IELVRLFAVELEHYEKIEGVPLTFDGKANRLASMVRGNLGAAMQGLAVVPLLVGYDLDAD 177 + ++EL + F R R +L A + ++ G+ Sbjct: 94 TYQLGFHSIELNEPPLVHTAASLFKEMCYRY----REDLMAGI-------IIAGW----- 137 Query: 178 DESRAGRIVSYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDSDEETALRAAIESLY 237 D G++ Y V G R + GSGS + + Y +E L+ +L Sbjct: 138 DPQEGGQV--YSVPMGGMMVRQSFAIGGSGSSYIYGYVDATYREGMTKEECLQFTANALA 195 Query: 238 DAADDDSATGG 248 A + D ++GG Sbjct: 196 LAMERDGSSGG 206 >5VFT-S nrPDB Length = 213 Score = 40.0 bits (92), Expect = 0.001, Method: Compositional matrix adjust. Identities = 38/152 (25%), Positives = 65/152 (42%), Gaps = 10/152 (6%) Query: 64 HGTTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAGTAGIAIELVRL 123 +G TI+A+ + ++A D R ++G I +RD K Y + + G +G G + L ++ Sbjct: 8 NGGTILAIAGEDFAIVASDTRLSEGFSIHTRDSPKCYKLTDKTVIGCSGFHGDCLTLTKI 67 Query: 124 FAVELEHYEKIEGVPLTFDGKANRLASMVRGNLGAAMQGLAVVPLLVGYDLDADDESRAG 183 L+ Y+ +T +A+M L + P V + DE G Sbjct: 68 IEARLKMYKHSNNKAMT----TGAIAAM----LSTILYSRRFFPYYVYNIIGGLDEEGKG 119 Query: 184 RIVSYDVVGGRYEERAGYHAVGSGSLFAKSAL 215 + S+D VG +R + A GS S + L Sbjct: 120 AVYSFDPVGSY--QRDSFKAGGSASAMLQPLL 149 >5JI2-A nrPDB Length = 184 Score = 40.0 bits (92), Expect = 0.001, Method: Compositional matrix adjust. Identities = 26/68 (38%), Positives = 40/68 (58%), Gaps = 1/68 (1%) Query: 66 TTIVALTYKGGVLLAGDRRATQGNLIASRDVEKV-YVTDEYSAAGIAGTAGIAIELVRLF 124 TTIV++ G V++AGD +AT GN + +V+KV + ++ AG AG A L LF Sbjct: 2 TTIVSVRRNGHVVIAGDGQATLGNTVMKGNVKKVRRLYNDKVIAGFAGGTADAFTLFELF 61 Query: 125 AVELEHYE 132 +LE ++ Sbjct: 62 ERKLEMHQ 69 >5FMG-I nrPDB Length = 229 Score = 40.0 bits (92), Expect = 0.001, Method: Compositional matrix adjust. Identities = 46/184 (25%), Positives = 80/184 (43%), Gaps = 14/184 (7%) Query: 66 TTIVALTYKGGVLLAGDRRATQGNLIASRDVEKV-YVTDEYSAAGIAGTAGIAIELVRLF 124 TTI L + V+L D RAT+G ++A ++ K+ Y++ AG AG AG +E L+ Sbjct: 1 TTICGLVCQNAVILGADTRATEGPIVADKNCSKLHYISKNIWCAG-AGVAG-DLEHTTLW 58 Query: 125 AVELEHYEKIEGVPLTFDGKANRLASMVRGNLGAAMQGLAVVPLLVGYDLDADDESRAGR 184 L+H ++ + + + S + L QG V +++G +D + Sbjct: 59 ---LQHNVELHRLNTNTQPRVSMCVSRLTQEL-FKYQGYKVCAIVLG-GVDVNGPQL--- 110 Query: 185 IVSYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDSDEETALRAAIESLYDAADDDS 244 Y + + A+GSGSL A + L+ Y + E E++ +D Sbjct: 111 ---YGIHPHGSSCLLPFTALGSGSLNAMAVLEAKYRDNMTIEEGKNLVCEAICAGIFNDL 167 Query: 245 ATGG 248 +GG Sbjct: 168 GSGG 171 >6AVO-B nrPDB Length = 234 Score = 39.3 bits (90), Expect = 0.002, Method: Compositional matrix adjust. Identities = 48/194 (24%), Positives = 83/194 (42%), Gaps = 34/194 (17%) Query: 66 TTIVALTYKGGVLLAGDRRATQGNLIASRDVEKV-YVTDEYSAAGIAGTAGIAIELVRLF 124 TTI L ++ GV+L D RAT +++A + EK+ ++ + G AG A A R+ Sbjct: 1 TTIAGLVFQDGVILGADTRATNDSVVADKSCEKIHFIAPKIYCCG-AGVAADAEMTTRMV 59 Query: 125 AVELEHYEKIEGVPLTFDGKANRLASMVR----------GNLGAAMQGLAVVPLLVGYDL 174 A ++E + G+ R+A++ R G++GA++ ++ G DL Sbjct: 60 ASKMELHA-------LSTGREPRVATVTRILRQTLFRYQGHVGASL-------IVGGVDL 105 Query: 175 DADDESRAGRIVSYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDSDEETALRAAIE 234 Y V R + A+GSG A + L+ + P+ E A +E Sbjct: 106 TGPQ--------LYGVHPHGSYSRLPFTALGSGQDAALAVLEDRFQPNMTLEAAQGLLVE 157 Query: 235 SLYDAADDDSATGG 248 ++ D +GG Sbjct: 158 AVTAGILGDLGSGG 171 >6EPC-1 nrPDB Length = 238 Score = 38.9 bits (89), Expect = 0.002, Method: Compositional matrix adjust. Identities = 46/191 (24%), Positives = 76/191 (39%), Gaps = 25/191 (13%) Query: 65 GTTIVALTYKGGVLLAGDRRATQGNLIASRDVEK-------VYVTDEYSAAGIAGTAGIA 117 GTTI+A+ + GGV+L D R T G+ IA+R +K ++ SAA A Sbjct: 33 GTTIMAVQFDGGVVLGADSRTTTGSYIANRVTDKLTPIHDHIFCCRSGSAADTQAVADAV 92 Query: 118 IELVRLFAVELEHYEKIEGVPLTFDGKANRLASMVRGNLGAAMQGLAVVPLLVGYDLDAD 177 + ++EL + F R R +L A + ++ G+ Sbjct: 93 TYQLGFHSIELNEPPLVHTAASLFKEMCYRY----REDLMAGI-------IIAGW----- 136 Query: 178 DESRAGRIVSYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDSDEETALRAAIESLY 237 D G++ Y V G R + GSGS + + Y ++ L+ +L Sbjct: 137 DPQEGGQV--YSVPMGGMMVRQSFAIGGSGSSYIYGYVDATYREGMTKDECLQFTANALA 194 Query: 238 DAADDDSATGG 248 A + D ++GG Sbjct: 195 LAMERDGSSGG 205 >3TY6-A nrPDB Length = 183 Score = 38.5 bits (88), Expect = 0.004, Method: Compositional matrix adjust. Identities = 25/72 (34%), Positives = 36/72 (50%), Gaps = 6/72 (8%) Query: 64 HGTTIVALTYKGGVLLAGDRRATQGNLIA----SRDVEKVYVTDEYSAAGIAGTAGIAIE 119 H TTI A+ + G +AGD + T GN + +R V K++ AG AG+ A Sbjct: 8 HATTIFAVHHNGECAMAGDGQVTMGNAVVMKHTARKVRKLF--QGKVLAGFAGSVADAFT 65 Query: 120 LVRLFAVELEHY 131 L +F +LE Y Sbjct: 66 LFEMFEGKLEEY 77 >6HV7-H nrPDB Length = 226 Score = 38.1 bits (87), Expect = 0.004, Method: Compositional matrix adjust. Identities = 44/187 (23%), Positives = 83/187 (44%), Gaps = 22/187 (11%) Query: 66 TTIVALTYKGGVLLAGDRRATQGNLIASRDVEKV-YVTDEYSAAGIAGTAGIAIELVRLF 124 TTI L ++ GV+L D RAT +++A + EK+ ++ + G AG A A + +L Sbjct: 1 TTIAGLVFQDGVILGADTRATNDSVVADKSCEKIHFIAPKIYCCG-AGVAADAEAVTQLI 59 Query: 125 AVELEHYEKIEGVPLTFDGKANRLAS---MVRGNLGAAMQGLAVVPLLVGYDLDADDESR 181 +E + + + R+ S M++ +L + ++ G D Sbjct: 60 GSNIELHS-------LYTSREPRVVSALQMLKQHLFKYQGHIGAYLIVAGVD------PT 106 Query: 182 AGRIVSYDVVGGRYEERAGYH-AVGSGSLFAKSALKKIYSPDSDEETALRAAIESLYDAA 240 + S G GY+ ++GSGSL A + L+ + D +E A++ A +++ Sbjct: 107 GSHLFSIHAHGST---DVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGI 163 Query: 241 DDDSATG 247 +D +G Sbjct: 164 WNDLGSG 170 >5LEZ-N nrPDB Length = 205 Score = 37.7 bits (86), Expect = 0.006, Method: Compositional matrix adjust. Identities = 46/190 (24%), Positives = 75/190 (39%), Gaps = 25/190 (13%) Query: 66 TTIVALTYKGGVLLAGDRRATQGNLIASRDVEK-------VYVTDEYSAAGIAGTAGIAI 118 TTI+A+ + GGV+L D R T G+ IA+R +K ++ SAA A Sbjct: 1 TTIMAVQFDGGVVLGADSRTTTGSYIANRVTDKLTPIHDRIFCCRSGSAADTQAVADAVT 60 Query: 119 ELVRLFAVELEHYEKIEGVPLTFDGKANRLASMVRGNLGAAMQGLAVVPLLVGYDLDADD 178 + ++EL + F R R +L A + ++ G+ D Sbjct: 61 YQLGFHSIELNEPPLVHTAASLFKEMCYRY----REDLMAGI-------IIAGW-----D 104 Query: 179 ESRAGRIVSYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDSDEETALRAAIESLYD 238 G++ Y V G R + GSGS + + Y +E L+ +L Sbjct: 105 PQEGGQV--YSVPMGGMMVRQSFAIGGSGSSYIYGYVDATYREGMTKEECLQFTANALAL 162 Query: 239 AADDDSATGG 248 A + D ++GG Sbjct: 163 AMERDGSSGG 172 >2KU2-A nrPDB Length = 237 Score = 37.7 bits (86), Expect = 0.006, Method: Compositional matrix adjust. Identities = 43/189 (22%), Positives = 80/189 (42%), Gaps = 10/189 (5%) Query: 64 HGTTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAGTAGIAIELVRL 123 G+T + + + GVLL D++ + LI +EK+ + D+Y AA +G A LV Sbjct: 37 KGSTALGMKFANGVLLISDKK-VRSRLIEQNSIEKIQLIDDYVAAVTSGLVADARVLVDF 95 Query: 124 FAVELEHYEKIEGVPLTFDGKANRLA-SMVRGNLGAAMQGLAVVPLLVGYDLDADDESRA 182 + + + G + + R+A M + ++ V + G D Sbjct: 96 ARISAQQEKVTYGSLVNIENLVKRVADQMQQYTQYGGVRPYGVSLIFAGID------QIG 149 Query: 183 GRIVSYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDSDEETALRAAIESLYDAADD 242 R+ D G E +A A+GSG S L++ Y + E+ A+ I++L + ++ Sbjct: 150 PRLFDCDPAGTINEYKA--TAIGSGKDAVVSFLEREYKENLPEKEAVTLGIKALKSSLEE 207 Query: 243 DSATGGPDL 251 P++ Sbjct: 208 GEELKAPEI 216 >5FMG-E nrPDB Length = 256 Score = 37.0 bits (84), Expect = 0.011, Method: Compositional matrix adjust. Identities = 23/70 (32%), Positives = 35/70 (50%), Gaps = 1/70 (1%) Query: 65 GTTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAGTAGIAIELVRLF 124 G+T V + GV+LA +RR + LI VEK+ D++ ++G A L+ Sbjct: 34 GSTAVGICVNDGVILASERRIS-STLIEKDSVEKLLSIDDHIGCAMSGLMADARTLIDYA 92 Query: 125 AVELEHYEKI 134 VE HY+ I Sbjct: 93 RVECNHYKFI 102 >3UNF-N nrPDB Length = 199 Score = 36.6 bits (83), Expect = 0.014, Method: Compositional matrix adjust. Identities = 52/207 (25%), Positives = 90/207 (43%), Gaps = 25/207 (12%) Query: 66 TTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAGTAGIAIELVRLFA 125 TTI+A+ + GGV++ D R + G + +R +K+ + ++G+A A + + A Sbjct: 1 TTIMAVEFDGGVVVGSDSRVSAGTAVVNRVFDKLSPLHQRIFCALSGSAADAQAIADMAA 60 Query: 126 VELEHYEKIEGVPLTFDGKANRLASM---VRGNLGAAMQGLAVVPLLVGYDLDADDESRA 182 +LE + P AN + ++ R +L A + ++ G+ D+ Sbjct: 61 YQLELHGLELEEPPLVLAAANVVKNISYKYREDLLAHL-------IVAGW-----DQREG 108 Query: 183 GRIVSYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDSDEETALRAAIESLYDAADD 242 G++ Y +GG R + GSGS + + Y P E R ++ A + Sbjct: 109 GQV--YGTMGGML-IRQPFTIGGSGSSYIYGYVDAAYKPGMTPEECRRFTTNAITLAMNR 165 Query: 243 DSATGGPDLTRGIYPTAVTITQAGAVH 269 D ++GG IY VTIT AG H Sbjct: 166 DGSSGGV-----IY--LVTITAAGVDH 185 >5FMG-H nrPDB Length = 252 Score = 36.2 bits (82), Expect = 0.017, Method: Compositional matrix adjust. Identities = 18/68 (26%), Positives = 37/68 (54%), Gaps = 3/68 (4%) Query: 66 TTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDE---YSAAGIAGTAGIAIELVR 122 TTI+ + Y GV+LA D R + G I+++ K+ +E +G + + IE+++ Sbjct: 1 TTIIGIIYDNGVMLACDSRTSSGTFISNKCSRKINRINENLYVCRSGASAHSQKIIEIIK 60 Query: 123 LFAVELEH 130 + V +++ Sbjct: 61 HYCVSMKN 68 >6J30-C nrPDB Length = 258 Score = 35.8 bits (81), Expect = 0.023, Method: Compositional matrix adjust. Identities = 42/186 (22%), Positives = 77/186 (41%), Gaps = 12/186 (6%) Query: 64 HGTTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAGTAGIAIELVRL 123 H T + + G++LA +R+ T L EK+Y ++ A +AG A L+ Sbjct: 31 HAGTAIGIMASDGIVLAAERKVTSTLLEQDTSTEKLYKLNDKIAVAVAGLTADAEILINT 90 Query: 124 FAVELEHYEKIEGVPLTFDGKANRLASMVRG-NLGAAMQGLAVVPLLVGYDLDADDESRA 182 + ++Y K + + RL+ + +G ++ V + GYD R Sbjct: 91 ARIHAQNYLKTYNEDIPVEILVRRLSDIKQGYTQHGGLRPFGVSFIYAGYD------DRY 144 Query: 183 GRIVSYDVVGGRYEERAGYHA--VGSGSLFAKSALKKIYSPDSDEETALRAAIESLYDAA 240 G + G Y G+ A VG+ + A++ L+ Y D + A+ A+++L Sbjct: 145 GYQLYTSNPSGNY---TGWKAISVGANTSAAQTLLQMDYKDDMKVDDAIELALKTLSKTT 201 Query: 241 DDDSAT 246 D + T Sbjct: 202 DSSALT 207 >3UNE-I nrPDB Length = 205 Score = 35.8 bits (81), Expect = 0.024, Method: Compositional matrix adjust. Identities = 42/185 (22%), Positives = 75/185 (40%), Gaps = 10/185 (5%) Query: 64 HGTTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAGTAGIAIELVRL 123 +G ++A+ K V +A DRR + + D +K++ + G+AG A + + Sbjct: 7 NGGAVMAMKGKNCVAIAADRRFGIQAQMVTTDFQKIFPMGDRLYIGLAGLATDVQTVAQR 66 Query: 124 FAVELEHYEKIEGVPLTFDGKANRLASMVRGNLGAAMQGLAVV-PLLVGYDLDADDESRA 182 L YE EG + K L SMV L G P++ G D ++ Sbjct: 67 LKFRLNLYELKEGRQI----KPYTLMSMVANLLYEKRFGPYYTEPVIAG----LDPKTFK 118 Query: 183 GRIVSYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDSDEETALRAAIESLYDAADD 242 I S D++G + G+ S + ++ P+ D E +++ +A D Sbjct: 119 PFICSLDLIGCPMVTD-DFVVSGTCSEQMYGMCESLWEPNMDPEHLFETISQAMLNAVDR 177 Query: 243 DSATG 247 D+ +G Sbjct: 178 DAVSG 182 >2Z3B-A nrPDB Length = 180 Score = 35.0 bits (79), Expect = 0.035, Method: Compositional matrix adjust. Identities = 24/72 (33%), Positives = 36/72 (50%), Gaps = 6/72 (8%) Query: 64 HGTTIVALTYKGGVLLAGDRRATQGNLIA----SRDVEKVYVTDEYSAAGIAGTAGIAIE 119 H TTI A+ +KG ++GD + T G + +R V K++ + AG AG+ A Sbjct: 4 HATTIFAVQHKGRSAMSGDGQVTFGQAVVMKHTARKVRKLF--NGKVLAGFAGSVADAFT 61 Query: 120 LVRLFAVELEHY 131 L F +LE Y Sbjct: 62 LFEKFEAKLEEY 73 >4Y8P-I nrPDB Length = 205 Score = 33.9 bits (76), Expect = 0.095, Method: Compositional matrix adjust. Identities = 46/189 (24%), Positives = 81/189 (42%), Gaps = 19/189 (10%) Query: 64 HGTTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAGTAGIAIELVRL 123 +G +VA+T K V +A D R +L S EK++ + GI G A L + Sbjct: 8 NGGIVVAMTGKDCVAIACDLRLGSQSLGVSNKFEKIFHYG-HVFLGITGLATDVTTLNEM 66 Query: 124 FAVELEHYEKIEG---VPLTFDGKANRLASMVRGNLGAAMQGLAVVPLLVGYDLDADDES 180 F + Y+ E P TF + +S+ G G P++ G + S Sbjct: 67 FRYKTNLYKLKEERAIEPETFTQLVS--SSLYERRFGPYFVG----PVVAGIN------S 114 Query: 181 RAGR--IVSYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDSDEETALRAAIESLYD 238 ++G+ I +D++G +E + G+ S + +Y P+ + E ++L + Sbjct: 115 KSGKPFIAGFDLIGC-IDEAKDFIVSGTASDQLFGMCESLYEPNLEPEDLFETISQALLN 173 Query: 239 AADDDSATG 247 AAD D+ +G Sbjct: 174 AADRDALSG 182 >6GOP-M nrPDB Length = 246 Score = 33.1 bits (74), Expect = 0.15, Method: Compositional matrix adjust. Identities = 14/48 (29%), Positives = 29/48 (60%) Query: 65 GTTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAG 112 GT+++++ Y GV++A D + G+L+ VE++ + + GI+G Sbjct: 21 GTSVISMKYDNGVIIAADNLGSYGSLLRFNGVERLIPVGDNTVVGISG 68 >5FMG-C nrPDB Length = 246 Score = 32.7 bits (73), Expect = 0.18, Method: Compositional matrix adjust. Identities = 40/165 (24%), Positives = 73/165 (44%), Gaps = 18/165 (10%) Query: 64 HGTTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAGT---AGIAIEL 120 + + + L K GV+L D+ + + + EK+Y D++ G+AG A I I Sbjct: 30 NASITIGLITKDGVILGADKVFISKLIDKANNYEKIYKIDKHIFCGVAGLNADANILINQ 89 Query: 121 VRLFAVE-LEHYEKIEGVPLTFDGKANRLASMVRGNLGAAMQGLAVVPLLVGYDLDADDE 179 RL+A L +Y +++ V + S + ++ V L+ GYD Sbjct: 90 SRLYAQRYLYNYNEVQPVSQLVVQICDIKQSYTQ---YGGLRPYGVSFLIGGYD------ 140 Query: 180 SRAGRIVSYDVVGGRYEERAGYH--AVGSGSLFAKSALKKIYSPD 222 ++ G + + G Y +G+ A+G+ +L A S LK+ + D Sbjct: 141 TKDGYQLYHTDPSGNY---SGWFATAIGTNNLTASSVLKQEWKND 182 >6HE5-A nrPDB Length = 247 Score = 32.7 bits (73), Expect = 0.19, Method: Compositional matrix adjust. Identities = 22/81 (27%), Positives = 37/81 (45%), Gaps = 1/81 (1%) Query: 32 GHAPELLPENRIGHRSHSTRGGDGMESGDLAPHGTTIVALTYKGGVLLAGDRRATQGNLI 91 GH P++ + I S R + + G T + + K GV+L D+R L+ Sbjct: 2 GHLPQMGYDRAITVFSPDGRLFQVEYAREAVKRGATAIGIKCKEGVILIADKRVG-SKLL 60 Query: 92 ASRDVEKVYVTDEYSAAGIAG 112 + +EK+Y DE+ A +G Sbjct: 61 EADTIEKIYKIDEHICAATSG 81 >1OFH-G nrPDB Length = 174 Score = 31.6 bits (70), Expect = 0.37, Method: Compositional matrix adjust. Identities = 23/70 (32%), Positives = 37/70 (52%), Gaps = 5/70 (7%) Query: 66 TTIVALTYKGGVLLAGDRRATQGNLIA---SRDVEKVYVTDEYSAAGIAGTAGIAIELVR 122 TTIV++ G V++ GD + + GN + +R V ++Y + AG AG A L Sbjct: 1 TTIVSVRRNGQVVVGGDGQVSLGNTVMKGNARKVRRLY--NGKVLAGFAGGTADAFTLFE 58 Query: 123 LFAVELEHYE 132 LF +LE ++ Sbjct: 59 LFERKLEMHQ 68 >5DT9-A nrPDB Length = 387 Score = 31.2 bits (69), Expect = 0.56, Method: Compositional matrix adjust. Identities = 30/118 (25%), Positives = 47/118 (39%), Gaps = 20/118 (16%) Query: 167 PLLVGYDLDADDESRAGRIVSYDVVGGRYEERAGY-HAVGSGSLFAKSALKKIYSPDSDE 225 P + GY L+ G+ ++ Y E G H SL K+ + K+Y + + Sbjct: 260 PHIAGYGLE-------GKARGTTMIFNSYCEFLGSAHCANPASLLPKAPVPKVYLERAWD 312 Query: 226 ETALRAAIESLYDAADDDS-------ATGGPDLTRGIYP-----TAVTITQAGAVHVS 271 E LR + +YD DD+ G DL R Y +AVT+ H++ Sbjct: 313 EETLRTLTQIIYDVRKDDAQFRREIHQPGAFDLMRKHYWDRREYSAVTLAGGADCHLA 370 >3NZW-L nrPDB Length = 241 Score = 30.4 bits (67), Expect = 0.86, Method: Compositional matrix adjust. Identities = 39/141 (27%), Positives = 57/141 (40%), Gaps = 13/141 (9%) Query: 64 HGTTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAGTAGIAIELVRL 123 +G TI+ + + +LAGD R I SR KV+ + G A LV+ Sbjct: 27 NGGTILGIAGEDFAVLAGDTRNITDYSINSRYEPKVFDCGDNIVMSANGFAADGDALVKR 86 Query: 124 FAVELEHYEKIEGVPLTFDGKANRLA--SMVRGNLGAAMQGLAVVPLLVGYDLDADDESR 181 F ++ Y FD +L+ S R N+ + G P V + DE Sbjct: 87 FKNSVKWYH--------FDHNDKKLSINSAAR-NIQHLLYGKRFFPYYVHTIIAGLDEDG 137 Query: 182 AGRIVSYDVVGG--RYEERAG 200 G + S+D VG R + RAG Sbjct: 138 KGAVYSFDPVGSYEREQCRAG 158 >5GJQ-g nrPDB Length = 264 Score = 30.4 bits (67), Expect = 0.88, Method: Compositional matrix adjust. Identities = 12/48 (25%), Positives = 29/48 (60%) Query: 65 GTTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAG 112 GT+++ + ++GGV++A D + G+L R++ ++ + + G +G Sbjct: 53 GTSVLGVKFEGGVVIAADMLGSYGSLARFRNISRIMRVNNSTMLGASG 100 >5LF6-M nrPDB Length = 219 Score = 30.0 bits (66), Expect = 1.1, Method: Compositional matrix adjust. Identities = 12/48 (25%), Positives = 29/48 (60%) Query: 65 GTTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAG 112 GT+++ + ++GGV++A D + G+L R++ ++ + + G +G Sbjct: 8 GTSVLGVKFEGGVVIAADMLGSYGSLARFRNISRIMRVNNSTMLGASG 55 >5LE5-B nrPDB Length = 261 Score = 30.0 bits (66), Expect = 1.3, Method: Compositional matrix adjust. Identities = 22/65 (33%), Positives = 29/65 (44%), Gaps = 3/65 (4%) Query: 64 HGTTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDE---YSAAGIAGTAGIAIEL 120 H T + + GVLLA +RR L EK+Y +E S AGI A + Sbjct: 30 HAGTCLGILANDGVLLAAERRNIHKLLDEVFFSEKIYKLNEDMACSVAGITSDANVLTNE 89 Query: 121 VRLFA 125 +RL A Sbjct: 90 LRLIA 94 >5FGG-F nrPDB Length = 288 Score = 29.6 bits (65), Expect = 1.6, Method: Compositional matrix adjust. Identities = 42/186 (22%), Positives = 79/186 (42%), Gaps = 17/186 (9%) Query: 64 HGTTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAGTAGIAIELVRL 123 +GTT + + GV+ A ++ T L+ ++V K+ V D + +G LV Sbjct: 33 NGTTSIGIKCNDGVVFAVEKLITSKLLVPQKNV-KIQVVDRHIGCVYSGLIPDGRHLVNR 91 Query: 124 FAVELEHYEKIEGVPLTFDGKANRLASMVRGN-LGAAMQGLAVVPLLVGYDLDADDESRA 182 E ++K+ P+ A+RL V+ + L +++ V + G D Sbjct: 92 GREEAASFKKLYKTPIPIPAFADRLGQYVQAHTLYNSVRPFGVSTIFGGVD------KNG 145 Query: 183 GRIVSYDVVGGRYEERAGYH--AVGSGSLFAKSALKKI--YSPDS-DEETALRAAIESLY 237 + + G + GY A G G AK+ L+K+ + P+ A++ A + +Y Sbjct: 146 AHLYMLEPSGSYW----GYKGAATGKGRQSAKAELEKLVDHHPEGLSAREAVKQAAKIIY 201 Query: 238 DAADDD 243 A +D+ Sbjct: 202 LAHEDN 207 >6FVW-g nrPDB Length = 245 Score = 29.6 bits (65), Expect = 1.8, Method: Compositional matrix adjust. Identities = 22/92 (23%), Positives = 41/92 (44%), Gaps = 1/92 (1%) Query: 64 HGTTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAGTAGIAIELVRL 123 +GTT + + GV+ A ++ T L+ ++V K+ V D + +G LV Sbjct: 30 NGTTSIGIKCNDGVVFAVEKLITSKLLVPQKNV-KIQVVDRHIGCVYSGLIPDGRHLVNR 88 Query: 124 FAVELEHYEKIEGVPLTFDGKANRLASMVRGN 155 E ++K+ P+ A+RL V+ + Sbjct: 89 GREEAASFKKLYKTPIPIPAFADRLGQYVQAH 120 >3N5I-A nrPDB Length = 373 Score = 29.6 bits (65), Expect = 1.8, Method: Compositional matrix adjust. Identities = 33/97 (34%), Positives = 43/97 (44%), Gaps = 29/97 (29%) Query: 24 SSFTDYLRGHAPE------LLP------ENRI----GH---RSHSTRGGDGMESGDLAPH 64 S D+ G PE LLP +NR+ GH R H DG + G +A Sbjct: 108 QSMMDWSVGKVPEEALFSRLLPVVAETLDNRLNDVFGHGLTRDHVFAALDGAKGGPVAEG 167 Query: 65 ----GTTIVALTYKGG------VLLAGDRRATQGNLI 91 GT ++A T+KGG V+ AGD R T G L+ Sbjct: 168 NVGGGTGMIAYTFKGGIGTSSRVVSAGDTRYTVGVLV 204 >4FZC-A nrPDB Length = 250 Score = 29.3 bits (64), Expect = 2.2, Method: Compositional matrix adjust. Identities = 25/94 (26%), Positives = 44/94 (46%), Gaps = 2/94 (2%) Query: 148 LASMVRGNLGAAMQGLAVVPLLVGYDLDADDESRAGRIVSYDVVGGRYEERAGYHAVGSG 207 L S V + A Q V P V + DE + D G + +A A+G G Sbjct: 110 LVSEVAKIMQEATQSGGVRPFGVSLLIAGHDEFNGFSLYQVDPSGSYFPWKA--TAIGKG 167 Query: 208 SLFAKSALKKIYSPDSDEETALRAAIESLYDAAD 241 S+ AK+ L+K ++ + + E A+ A+ +L ++ + Sbjct: 168 SVAAKTFLEKRWNDELELEDAIHIALLTLKESVE 201 >2Z5C-C nrPDB Length = 262 Score = 28.9 bits (63), Expect = 3.0, Method: Compositional matrix adjust. Identities = 26/93 (27%), Positives = 45/93 (48%), Gaps = 11/93 (11%) Query: 20 GSNLSSFTDYLRGHAPELLPENRIGHRSHSTRGGDGMESGDLAPHGTTIVALTYKGGVLL 79 GS + ++Y RG PE R+ +S +E+ L G+T + + K GV+L Sbjct: 1 GSMFLTRSEYDRG-VSTFSPEGRLFQVEYS------LEAIKL---GSTAIGIATKEGVVL 50 Query: 80 AGDRRATQGNLIASRDVEKVYVTDEYSAAGIAG 112 ++RAT L+ S +EK+ D + ++G Sbjct: 51 GVEKRAT-SPLLESDSIEKIVEIDRHIGCAMSG 82 >1VH3-A nrPDB Length = 262 Score = 28.9 bits (63), Expect = 3.0, Method: Compositional matrix adjust. Identities = 24/80 (30%), Positives = 41/80 (51%), Gaps = 5/80 (6%) Query: 70 ALTYKGGVLLAGDRRAT---QGNLIASRDVEKVYVTDEY-SAAGI-AGTAGIAIELVRLF 124 LT K G +L R + + +DV+KV ++D Y GI A AG + V+ Sbjct: 144 VLTDKDGYVLYFSRSVIPYDRDQFMNLQDVQKVQLSDAYLRHIGIYAYRAGFIKQYVQWA 203 Query: 125 AVELEHYEKIEGVPLTFDGK 144 +LE+ EK+E + + ++G+ Sbjct: 204 PTQLENLEKLEQLRVLYNGE 223 >2YWH-A nrPDB Length = 600 Score = 28.5 bits (62), Expect = 3.2, Method: Compositional matrix adjust. Identities = 28/108 (25%), Positives = 47/108 (43%), Gaps = 6/108 (5%) Query: 135 EGVPLTFDGKANRLASMVRGNLGAAMQGLAVVPLLVGYDLDADDESRAGRIVSYDVVGGR 194 EG L D A V A Q L ++P++ DL + D R + + +V+G Sbjct: 98 EGALLLIDASQGIEAQTVANFWKAVEQDLVIIPVINKIDLPSADVDRVKKQIE-EVLGLD 156 Query: 195 YEE---RAGYHAVGSGSLFAKSALKKIYSPDSDEETALRAAI-ESLYD 238 EE + +G + ++ + +I P D + L+A I +S YD Sbjct: 157 PEEAILASAKEGIGIEEIL-EAIVNRIPPPKGDPQKPLKALIFDSYYD 203 >4HO7-A nrPDB Length = 179 Score = 28.5 bits (62), Expect = 3.4, Method: Compositional matrix adjust. Identities = 45/170 (26%), Positives = 73/170 (42%), Gaps = 19/170 (11%) Query: 66 TTIVALTYKGGVLLAGDRRATQGN-LIASRDVEKVYVTDEYSAAGIAGTAGIAIELVRLF 124 TTI+++ V+L GDR+ T G ++A K+ ++ G AG+ AI L+ Sbjct: 1 TTILSVRKGDTVVLLGDRQVTLGERIVAKSSACKLRRINDDVVIGFAGSTADAISLME-- 58 Query: 125 AVELEHYEKIEGVPLTFDGKANRLASMVRGNLGAAMQGLAVVPLLVGYDLDADDESRAGR 184 +LE+ KI P A LA R + +++ L+ D + G Sbjct: 59 --KLEN--KIGEFPNQLTRAAVELAKEWRTDRALRRLEASLIVCSAEETLEIDGQ---GN 111 Query: 185 IVSYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDS-DEETALRAAI 233 +++ E G A+GSG FAK+A + + D D E R A+ Sbjct: 112 VIT--------PEADGIVAIGSGGTFAKAAARALIDVDGYDAEKIARKAM 153 >1G0U-D nrPDB Length = 241 Score = 27.7 bits (60), Expect = 5.9, Method: Compositional matrix adjust. Identities = 15/48 (31%), Positives = 27/48 (56%), Gaps = 1/48 (2%) Query: 65 GTTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAG 112 G+T + + K GV+L ++RAT L+ S +EK+ D + ++G Sbjct: 34 GSTAIGIATKEGVVLGVEKRAT-SPLLESDSIEKIVEIDRHIGCAMSG 80 >6EPE-7 nrPDB Length = 263 Score = 27.7 bits (60), Expect = 6.0, Method: Compositional matrix adjust. Identities = 11/48 (22%), Positives = 28/48 (58%) Query: 65 GTTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAG 112 GT+++ + + GV++A D + G+L R++ ++ ++ + G +G Sbjct: 52 GTSVLGVKFDCGVVIAADMLGSYGSLARFRNISRIMRVNDSTMLGASG 99 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 1Q5R-H nrPDB 365 e-101 2JAY-A nrPDB 270 7e-73 1Q5Q-H nrPDB 260 4e-70 3NZW-K nrPDB 238 3e-63 5L64-K nrPDB 233 5e-62 5CZ8-K nrPDB 231 3e-61 5LZP-A nrPDB 225 2e-59 6EPF-5 nrPDB 218 2e-57 5LN3-5 nrPDB 216 7e-57 3UNB-K nrPDB 211 4e-55 6AVO-C nrPDB 208 2e-54 3UNF-K nrPDB 205 2e-53 5L4G-U nrPDB 191 2e-49 5FMG-L nrPDB 184 5e-47 3IPM-H nrPDB 180 7e-46 6EPF-6 nrPDB 180 7e-46 3H4P-a nrPDB 177 6e-45 5MPC-h nrPDB 173 8e-44 5FMG-I nrPDB 169 1e-42 6EPF-2 nrPDB 168 3e-42 5GJQ-a nrPDB 168 3e-42 5L4G-8 nrPDB 167 6e-42 6HEC-1 nrPDB 167 7e-42 6HUB-H nrPDB 166 7e-42 5VFT-S nrPDB 166 2e-41 5FGI-H nrPDB 164 4e-41 6AVO-A nrPDB 163 7e-41 6AVO-B nrPDB 162 2e-40 3UNH-H nrPDB 160 5e-40 3H4P-A nrPDB 149 1e-36 5FMG-N nrPDB 102 2e-22 5JI2-A nrPDB 77 1e-14 Sequences not found previously or not previously below threshold: 5L5A-K nrPDB 229 1e-60 6EPC-1 nrPDB 168 4e-42 5LEZ-N nrPDB 165 2e-41 6HV7-H nrPDB 163 6e-41 3UNF-N nrPDB 154 5e-38 5FMG-M nrPDB 116 2e-26 6HE5-A nrPDB 109 1e-24 5FMG-E nrPDB 104 4e-23 3NZW-L nrPDB 104 4e-23 3UNE-I nrPDB 104 6e-23 6J30-C nrPDB 99 2e-21 5FMG-H nrPDB 98 6e-21 2KU2-A nrPDB 97 9e-21 5FGE-J nrPDB 93 2e-19 4Y8P-I nrPDB 91 6e-19 3WXR-K nrPDB 90 9e-19 5FMG-C nrPDB 87 1e-17 5FMG-J nrPDB 86 2e-17 5LEZ-C nrPDB 85 4e-17 5LE5-B nrPDB 84 7e-17 5GJR-F nrPDB 84 7e-17 2Z5C-C nrPDB 84 8e-17 1G0U-D nrPDB 81 4e-16 4YA5-C nrPDB 79 2e-15 6FVW-g nrPDB 79 3e-15 5FGG-F nrPDB 78 5e-15 5FMG-D nrPDB 74 6e-14 4FZC-A nrPDB 74 6e-14 5LF3-J nrPDB 74 9e-14 5FMG-B nrPDB 71 8e-13 6GOP-M nrPDB 69 3e-12 5LF0-A nrPDB 68 4e-12 5GJQ-g nrPDB 67 8e-12 5LF6-M nrPDB 67 9e-12 1OFH-G nrPDB 66 1e-11 6EPE-7 nrPDB 66 2e-11 5FMG-K nrPDB 64 7e-11 6EPD-G nrPDB 63 1e-10 3TY6-A nrPDB 61 5e-10 5FMG-F nrPDB 61 7e-10 4HO7-A nrPDB 59 2e-09 5T0I-L nrPDB 59 2e-09 2Z3B-A nrPDB 59 2e-09 3NZW-E nrPDB 58 4e-09 5FMG-G nrPDB 56 2e-08 1M4Y-A nrPDB 55 5e-08 5LOY-A nrPDB 52 2e-07 5NYW-A nrPDB 47 9e-06 5LOX-A nrPDB 45 4e-05 5NYF-A nrPDB 42 4e-04 1Q5Q-A nrPDB 37 0.007 6JO3-A nrPDB 31 0.82 5GZU-A nrPDB 28 6.5 5HH3-A nrPDB 27 9.6 >1Q5R-H nrPDB Length = 294 Score = 365 bits (936), Expect = e-101, Method: Composition-based stats. Identities = 293/294 (99%), Positives = 293/294 (99%) Query: 1 MTADRPALRTGDRDTRLSFGSNLSSFTDYLRGHAPELLPENRIGHRSHSTRGGDGMESGD 60 MTADRPALRTGDRDTRLSFGSNLSSFTDYLRGHAPELLPENRIGHRSHSTRGGDGMESGD Sbjct: 1 MTADRPALRTGDRDTRLSFGSNLSSFTDYLRGHAPELLPENRIGHRSHSTRGGDGMESGD 60 Query: 61 LAPHGTTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAGTAGIAIEL 120 LAPHGTTIVALTYKGGVLLAGDRRATQGNLIASRDVE VYVTDEYSAAGIAGTAGIAIEL Sbjct: 61 LAPHGTTIVALTYKGGVLLAGDRRATQGNLIASRDVEAVYVTDEYSAAGIAGTAGIAIEL 120 Query: 121 VRLFAVELEHYEKIEGVPLTFDGKANRLASMVRGNLGAAMQGLAVVPLLVGYDLDADDES 180 VRLFAVELEHYEKIEGVPLTFDGKANRLASMVRGNLGAAMQGLAVVPLLVGYDLDADDES Sbjct: 121 VRLFAVELEHYEKIEGVPLTFDGKANRLASMVRGNLGAAMQGLAVVPLLVGYDLDADDES 180 Query: 181 RAGRIVSYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDSDEETALRAAIESLYDAA 240 RAGRIVSYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDSDEETALRAAIESLYDAA Sbjct: 181 RAGRIVSYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDSDEETALRAAIESLYDAA 240 Query: 241 DDDSATGGPDLTRGIYPTAVTITQAGAVHVSEETTSELARRIVAERTEQGGSAR 294 DDDSATGGPDLTRGIYPTAVTITQAGAVHVSEETTSELARRIVAERTEQGGSAR Sbjct: 241 DDDSATGGPDLTRGIYPTAVTITQAGAVHVSEETTSELARRIVAERTEQGGSAR 294 >2JAY-A nrPDB Length = 291 Score = 270 bits (689), Expect = 7e-73, Method: Composition-based stats. Identities = 171/267 (64%), Positives = 201/267 (75%), Gaps = 9/267 (3%) Query: 22 NLSSFTDYLRGHAPELLPENRIGHRSHSTRGGDGMESGDLA-PHGTTIVALTYKGGVLLA 80 +LSSFTD+LR APELLP S GG + GD PHGTTIVAL Y GGV++A Sbjct: 21 DLSSFTDFLRRQAPELLPA--------SISGGAPLAGGDAQLPHGTTIVALKYPGGVVMA 72 Query: 81 GDRRATQGNLIASRDVEKVYVTDEYSAAGIAGTAGIAIELVRLFAVELEHYEKIEGVPLT 140 GDRR+TQGN+I+ RDV KVY+TD+Y+A GIAGTA +A+E RL+AVELEHYEK+EGVPLT Sbjct: 73 GDRRSTQGNMISGRDVRKVYITDDYTATGIAGTAAVAVEFARLYAVELEHYEKLEGVPLT 132 Query: 141 FDGKANRLASMVRGNLGAAMQGLAVVPLLVGYDLDADDESRAGRIVSYDVVGGRYEERAG 200 F GK NRLA MVRGNL AAMQGL +PLL GYD+ A D AGRIVS+D GG E G Sbjct: 133 FAGKINRLAIMVRGNLAAAMQGLLALPLLAGYDIHASDPQSAGRIVSFDAAGGWNIEEEG 192 Query: 201 YHAVGSGSLFAKSALKKIYSPDSDEETALRAAIESLYDAADDDSATGGPDLTRGIYPTAV 260 Y AVGSGSLFAKS++KK+YS +D ++ LR A+E+LYDAADDDSATGGPDL RGI+PTAV Sbjct: 193 YQAVGSGSLFAKSSMKKLYSQVTDGDSGLRVAVEALYDAADDDSATGGPDLVRGIFPTAV 252 Query: 261 TITQAGAVHVSEETTSELARRIVAERT 287 I GAV V E +ELAR I+ R+ Sbjct: 253 IIDADGAVDVPESRIAELARAIIESRS 279 >1Q5Q-H nrPDB Length = 235 Score = 260 bits (665), Expect = 4e-70, Method: Composition-based stats. Identities = 229/229 (100%), Positives = 229/229 (100%) Query: 66 TTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAGTAGIAIELVRLFA 125 TTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAGTAGIAIELVRLFA Sbjct: 1 TTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAGTAGIAIELVRLFA 60 Query: 126 VELEHYEKIEGVPLTFDGKANRLASMVRGNLGAAMQGLAVVPLLVGYDLDADDESRAGRI 185 VELEHYEKIEGVPLTFDGKANRLASMVRGNLGAAMQGLAVVPLLVGYDLDADDESRAGRI Sbjct: 61 VELEHYEKIEGVPLTFDGKANRLASMVRGNLGAAMQGLAVVPLLVGYDLDADDESRAGRI 120 Query: 186 VSYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDSDEETALRAAIESLYDAADDDSA 245 VSYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDSDEETALRAAIESLYDAADDDSA Sbjct: 121 VSYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDSDEETALRAAIESLYDAADDDSA 180 Query: 246 TGGPDLTRGIYPTAVTITQAGAVHVSEETTSELARRIVAERTEQGGSAR 294 TGGPDLTRGIYPTAVTITQAGAVHVSEETTSELARRIVAERTEQGGSAR Sbjct: 181 TGGPDLTRGIYPTAVTITQAGAVHVSEETTSELARRIVAERTEQGGSAR 229 >3NZW-K nrPDB Length = 287 Score = 238 bits (606), Expect = 3e-63, Method: Composition-based stats. Identities = 59/222 (26%), Positives = 93/222 (41%), Gaps = 17/222 (7%) Query: 64 HGTTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAGTAGIAIELVRL 123 HGTT +A ++GG+++A D RAT GN +AS+ V+KV + + +AG A Sbjct: 74 HGTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWETW 133 Query: 124 FAVELEHYEKIEGVPLTFDGKANRLASMVRGNLGAAMQGLAVVPLLVGYDLDADDESRAG 183 + +E E ++ + L+++V GA GL++ ++ GY Sbjct: 134 LGSQCRLHELREKERISVAAASKILSNLVYQYKGA---GLSMGTMICGY-----TRKEGP 185 Query: 184 RIVSYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDSDEETALRAAIESLYDAADDD 243 I D G R + VGSG FA L Y D E AL S+ AA D Sbjct: 186 TIYYVDSDGTRL--KGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRD 243 Query: 244 SATGGPDLTRGIYPTAVTITQAGAVHVSEETTSELARRIVAE 285 + +GG +T+ G ++ EL ++ E Sbjct: 244 AYSGGS-------VNLYHVTEDGWIYHGNHDVGELFWKVKEE 278 >5L64-K nrPDB Length = 211 Score = 233 bits (595), Expect = 5e-62, Method: Composition-based stats. Identities = 62/220 (28%), Positives = 94/220 (42%), Gaps = 18/220 (8%) Query: 66 TTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAGTAGIAIELVRLFA 125 TT +A ++ GV++A D RAT G IAS+ V+KV + Y +AG A RL A Sbjct: 1 TTTLAFKFRHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAADCSFWERLLA 60 Query: 126 VELEHYEKIEGVPLTFDGKANRLASMVRGNLGAAMQGLAVVPLLVGYDLDADDESRAGRI 185 + YE ++ + LA+MV G GL++ ++ G+D R + Sbjct: 61 RQCRIYELRNKERISVAAASKLLANMVYQYKG---MGLSMGTMICGWD------KRGPGL 111 Query: 186 VSYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDSDEETALRAAIESLYDAADDDSA 245 D G R +VGSGS++A L Y D E AL S+ AA D+ Sbjct: 112 YYVDSEGNRIS--GATFSVGSGSVYAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAY 169 Query: 246 TGGPDLTRGIYPTAVTITQAGAVHVSEETTSELARRIVAE 285 +GG +T+ G ++ EL ++ E Sbjct: 170 SGGS-------VNLYHVTEDGWIYHGNHDVGELFWKVKEE 202 >5CZ8-K nrPDB Length = 221 Score = 231 bits (589), Expect = 3e-61, Method: Composition-based stats. Identities = 58/222 (26%), Positives = 92/222 (41%), Gaps = 17/222 (7%) Query: 64 HGTTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAGTAGIAIELVRL 123 HGTT +A ++GG+++A D RAT GN +AS+ V+ V + + +AG A Sbjct: 8 HGTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKAVIEINPFLLGTMAGGAADCQFWETW 67 Query: 124 FAVELEHYEKIEGVPLTFDGKANRLASMVRGNLGAAMQGLAVVPLLVGYDLDADDESRAG 183 + +E E ++ + L+++V GA GL++ ++ GY Sbjct: 68 LGSQCRLHELREKERISVAAASKILSNLVYQYKGA---GLSMGTMICGY-----TRKEGP 119 Query: 184 RIVSYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDSDEETALRAAIESLYDAADDD 243 I D G R + VGSG FA L Y D E AL S+ AA D Sbjct: 120 TIYYVDSDGTRL--KGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRD 177 Query: 244 SATGGPDLTRGIYPTAVTITQAGAVHVSEETTSELARRIVAE 285 + +GG +T+ G ++ EL ++ E Sbjct: 178 AYSGGS-------VNLYHVTEDGWIYHGNHDVGELFWKVKEE 212 >5L5A-K nrPDB Length = 211 Score = 229 bits (584), Expect = 1e-60, Method: Composition-based stats. Identities = 53/220 (24%), Positives = 89/220 (40%), Gaps = 18/220 (8%) Query: 66 TTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAGTAGIAIELVRLFA 125 TT +A ++ GV+ A D RA+ G+ I++ V KV + Y ++G A L A Sbjct: 1 TTTLAFKFQHGVIAAVDSRASAGSYISALRVNKVIEINPYLLGTMSGCAADCQYWETLLA 60 Query: 126 VELEHYEKIEGVPLTFDGKANRLASMVRGNLGAAMQGLAVVPLLVGYDLDADDESRAGRI 185 E Y G ++ + L++M+ G GL++ ++ G+D + + Sbjct: 61 KECRLYYLRNGERISVSAASKLLSNMMCQYRG---MGLSMGSMICGWD------KKGPGL 111 Query: 186 VSYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDSDEETALRAAIESLYDAADDDSA 245 D G R + GSG+ +A L Y D E AL S+ AA D+ Sbjct: 112 YYVDEHGTRLS--GNMFSTGSGNTYAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAY 169 Query: 246 TGGPDLTRGIYPTAVTITQAGAVHVSEETTSELARRIVAE 285 +GG +T+ G ++ EL ++ E Sbjct: 170 SGGS-------VNLYHVTEDGWIYHGNHDVGELFWKVKEE 202 >5LZP-A nrPDB Length = 242 Score = 225 bits (573), Expect = 2e-59, Method: Composition-based stats. Identities = 148/221 (66%), Positives = 175/221 (79%) Query: 67 TIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAGTAGIAIELVRLFAV 126 TIVAL Y GGV++AGDRR+TQGN+I+ RDV KVY+TD+Y+A GIAGTA +A+E RL+AV Sbjct: 2 TIVALKYPGGVVMAGDRRSTQGNMISGRDVRKVYITDDYTATGIAGTAAVAVEFARLYAV 61 Query: 127 ELEHYEKIEGVPLTFDGKANRLASMVRGNLGAAMQGLAVVPLLVGYDLDADDESRAGRIV 186 ELEHYEK+EGVPLTF GK NRLA MVRGNL AAMQGL +PLL GYD+ A D AGRIV Sbjct: 62 ELEHYEKLEGVPLTFAGKINRLAIMVRGNLAAAMQGLLALPLLAGYDIHASDPQSAGRIV 121 Query: 187 SYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDSDEETALRAAIESLYDAADDDSAT 246 S+D GG E GY AVGSGSLFAKS++KK+YS +D ++ LR A+E+LYDAADDDSAT Sbjct: 122 SFDAAGGWNIEEEGYQAVGSGSLFAKSSMKKLYSQVTDGDSGLRVAVEALYDAADDDSAT 181 Query: 247 GGPDLTRGIYPTAVTITQAGAVHVSEETTSELARRIVAERT 287 GGPDL RGI+PTAV I GAV V E +ELAR I+ R+ Sbjct: 182 GGPDLVRGIFPTAVIIDADGAVDVPESRIAELARAIIESRS 222 >6EPF-5 nrPDB Length = 263 Score = 218 bits (556), Expect = 2e-57, Method: Composition-based stats. Identities = 63/215 (29%), Positives = 98/215 (45%), Gaps = 18/215 (8%) Query: 64 HGTTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAGTAGIAIELVRL 123 HGTT +A ++ GV++A D RAT G IAS+ V+KV + Y +AG A RL Sbjct: 58 HGTTTLAFKFQHGVIVAADSRATAGPYIASQTVKKVIEINPYLLGTMAGGAADCSFWERL 117 Query: 124 FAVELEHYEKIEGVPLTFDGKANRLASMVRGNLGAAMQGLAVVPLLVGYDLDADDESRAG 183 A + YE ++ + LA+MV G GL++ ++ G+D R Sbjct: 118 LARQCRIYELRNKERISVAAASKLLANMVYQYKG---MGLSMGTMICGWD------KRGP 168 Query: 184 RIVSYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDSDEETALRAAIESLYDAADDD 243 + D G R A +VGSGS++A + + YS D E A A ++Y A D Sbjct: 169 GLYYVDSEGNRISGTA--FSVGSGSVYAFGVMDRGYSYDLQVEEAYDLARRAIYQATYRD 226 Query: 244 SATGGPDLTRGIYPTAVTITQAGAVHVSEETTSEL 278 + +GG + + G + VS + ++L Sbjct: 227 AYSGGA-------VNLYHVREDGWIRVSSDNVADL 254 >5LN3-5 nrPDB Length = 263 Score = 216 bits (551), Expect = 7e-57, Method: Composition-based stats. Identities = 65/229 (28%), Positives = 102/229 (44%), Gaps = 18/229 (7%) Query: 53 GDGMESGDLAPHGTTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAG 112 G E G HGTT +A ++ GV++A D RAT G IAS+ V+KV + Y +AG Sbjct: 47 GVPEEPGIEMLHGTTTLAFKFRHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAG 106 Query: 113 TAGIAIELVRLFAVELEHYEKIEGVPLTFDGKANRLASMVRGNLGAAMQGLAVVPLLVGY 172 A RL A + YE ++ + LA+MV G GL++ ++ G+ Sbjct: 107 GAADCSFWERLLARQCRIYELRNKERISVAAASKLLANMVYQYKG---MGLSMGTMICGW 163 Query: 173 DLDADDESRAGRIVSYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDSDEETALRAA 232 D R + D G R +VGSGS++A + + YS D + E A A Sbjct: 164 D------KRGPGLYYVDSEGNRIS--GATFSVGSGSVYAYGVMDRGYSYDLEVEQAYDLA 215 Query: 233 IESLYDAADDDSATGGPDLTRGIYPTAVTITQAGAVHVSEETTSELARR 281 ++Y A D+ +GG + + G + VS + ++L + Sbjct: 216 RRAIYQATYRDAYSGGA-------VNLYHVREDGWIRVSSDNVADLHEK 257 >3UNB-K nrPDB Length = 205 Score = 211 bits (536), Expect = 4e-55, Method: Composition-based stats. Identities = 61/213 (28%), Positives = 95/213 (44%), Gaps = 18/213 (8%) Query: 66 TTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAGTAGIAIELVRLFA 125 TT +A + GV++A D RAT G IAS+ V+KV + Y +AG A RL A Sbjct: 1 TTTLAFKFLHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAADCSFWERLLA 60 Query: 126 VELEHYEKIEGVPLTFDGKANRLASMVRGNLGAAMQGLAVVPLLVGYDLDADDESRAGRI 185 + YE ++ + LA+MV G GL++ ++ G+D R + Sbjct: 61 RQCRIYELRNKERISVAAASKLLANMVYQYKG---MGLSMGTMICGWD------KRGPGL 111 Query: 186 VSYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDSDEETALRAAIESLYDAADDDSA 245 D G R A +VGSGS++A + + YS D E A A ++Y A D+ Sbjct: 112 YYVDSEGNRISGTA--FSVGSGSVYAYGVMDRGYSYDLKVEEAYDLARRAIYQATYRDAY 169 Query: 246 TGGPDLTRGIYPTAVTITQAGAVHVSEETTSEL 278 +GG + + G + VS + ++L Sbjct: 170 SGGA-------VNLYHVREDGWIRVSSDNVADL 195 >6AVO-C nrPDB Length = 204 Score = 208 bits (530), Expect = 2e-54, Method: Composition-based stats. Identities = 51/219 (23%), Positives = 87/219 (39%), Gaps = 18/219 (8%) Query: 66 TTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAGTAGIAIELVRLFA 125 TT +A ++ GV+ A D RA+ G+ I++ V KV + Y ++G A RL A Sbjct: 1 TTTLAFKFQHGVIAAVDSRASAGSYISALRVNKVIEINPYLLGTMSGCAADCQYWERLLA 60 Query: 126 VELEHYEKIEGVPLTFDGKANRLASMVRGNLGAAMQGLAVVPLLVGYDLDADDESRAGRI 185 E Y G ++ + L++M+ G GL++ ++ G+D + + Sbjct: 61 KECRLYYLRNGERISVSAASKLLSNMMCQYRG---MGLSMGSMICGWD------KKGPGL 111 Query: 186 VSYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDSDEETALRAAIESLYDAADDDSA 245 D G R + GSG+ +A + Y P+ E A ++ A DS Sbjct: 112 YYVDEHGTRLS--GNMFSTGSGNTYAYGVMDSGYRPNLSPEEAYDLGRRAIAYATHRDSY 169 Query: 246 TGGPDLTRGIYPTAVTITQAGAVHVSEETTSELARRIVA 284 +GG + + G V V S+L + Sbjct: 170 SGGV-------VNMYHMKEDGWVKVESTDVSDLLHQYRE 201 >3UNF-K nrPDB Length = 204 Score = 205 bits (521), Expect = 2e-53, Method: Composition-based stats. Identities = 51/219 (23%), Positives = 87/219 (39%), Gaps = 18/219 (8%) Query: 66 TTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAGTAGIAIELVRLFA 125 TT +A ++ GV++A D RAT G+ I+S + KV + Y ++G A RL A Sbjct: 1 TTTLAFKFQHGVIVAVDSRATAGSYISSLRMNKVIEINPYLLGTMSGCAADCQYWERLLA 60 Query: 126 VELEHYEKIEGVPLTFDGKANRLASMVRGNLGAAMQGLAVVPLLVGYDLDADDESRAGRI 185 E Y G ++ + L++M+ G GL++ ++ G+D + + Sbjct: 61 KECRLYYLRNGERISVSAASKLLSNMMLQYRG---MGLSMGSMICGWD------KKGPGL 111 Query: 186 VSYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDSDEETALRAAIESLYDAADDDSA 245 D G R + GSG+ +A + Y D E A ++ A D+ Sbjct: 112 YYVDDNGTRLS--GQMFSTGSGNTYAYGVMDSGYRQDLSPEEAYDLGRRAIAYATHRDNY 169 Query: 246 TGGPDLTRGIYPTAVTITQAGAVHVSEETTSELARRIVA 284 +GG + + G V V S+L + Sbjct: 170 SGGV-------VNMYHMKEDGWVKVESSDVSDLLYKYGE 201 >5L4G-U nrPDB Length = 241 Score = 191 bits (486), Expect = 2e-49, Method: Composition-based stats. Identities = 48/218 (22%), Positives = 82/218 (37%), Gaps = 19/218 (8%) Query: 39 PENRIGHRSHSTRGGDGMESGDLAPHGTTIVALTYKGGVLLAGDRRATQGNLIASRDVEK 98 P +G H G + +G TI+A+ + ++A D R ++G I +RD K Sbjct: 11 PGRDLGMEPHRAAGPLQLRFSPYVFNGGTILAIAGEDFAIVASDTRLSEGFSIHTRDSPK 70 Query: 99 VYVTDEYSAAGIAGTAGIAIELVRLFAVELEHYEKIEGVPLTFDGKANRLASMVRGNLGA 158 Y + + G +G G + L ++ L+ Y+ +T A L++++ Sbjct: 71 CYKLTDKTVIGCSGFHGDCLTLTKIIEARLKMYKHSNNKAMTTGAIAAMLSTILYSR--- 127 Query: 159 AMQGLAVVPLLVGYDLDADDESRAGRIVSYDVVGGRYEERAGYHAVGSGSLFAKSALKKI 218 P V + DE G + S+D VG +R + A GS S + L Sbjct: 128 -----RFFPYYVYNIIGGLDEEGKGAVYSFDPVGSY--QRDSFKAGGSASAMLQPLLDNQ 180 Query: 219 YSPD---------SDEETALRAAIESLYDAADDDSATG 247 + A+R + AA+ D TG Sbjct: 181 VGFKNMQNVEHVPLSLDRAMRLVKDVFISAAERDVYTG 218 >5FMG-L nrPDB Length = 211 Score = 184 bits (466), Expect = 5e-47, Method: Composition-based stats. Identities = 47/195 (24%), Positives = 86/195 (44%), Gaps = 11/195 (5%) Query: 66 TTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAGTAGIAIELVRLFA 125 TT +A +K G+++A D RA+ G+ I+S++VEK+ ++ +AG A + + Sbjct: 1 TTTLAFKFKDGIIVAVDSRASMGSFISSQNVEKIIEINKNILGTMAGGAADCLYWEKYLG 60 Query: 126 VELEHYEKIEGVPLTFDGKANRLASMVRGNLGAAMQGLAVVPLLVGYDLDADDESRAGRI 185 ++ YE ++ + L++++ G GL +L GYD + + Sbjct: 61 KIIKIYELRNNEKISVRAASTILSNILYQYKG---YGLCCGIILSGYDHTGFN------M 111 Query: 186 VSYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDSDEETALRAAIESLYDAADDDSA 245 D G + E + GSGS +A S L Y + + + A+ A ++Y A D Sbjct: 112 FYVDDSGKKVE--GNLFSCGSGSTYAYSILDSAYDYNLNLDQAVELARNAIYHATFRDGG 169 Query: 246 TGGPDLTRGIYPTAV 260 +GG I+ Sbjct: 170 SGGKVRVFHIHKNGY 184 >3IPM-H nrPDB Length = 217 Score = 180 bits (456), Expect = 7e-46, Method: Composition-based stats. Identities = 65/218 (29%), Positives = 94/218 (43%), Gaps = 18/218 (8%) Query: 65 GTTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAGTAGIAIELVRLF 124 GTT V +T K V++A +RR T N I ++ +K++ D Y+ IAG G A LVR Sbjct: 8 GTTTVGITLKDAVIMATERRVTMENFIMHKNGKKLFQIDTYTGMTIAGLVGDAQVLVRYM 67 Query: 125 AVELEHYEKIEGVPLTFDGKANRLASMVRGNLGAAMQGLAVVPLLVGYDLDADDESRAGR 184 ELE Y V + + A L++M L +V LLVG A Sbjct: 68 KAELELYRLQRRVNMPIEAVATLLSNM----LNQVKYMPYMVQLLVG------GIDTAPH 117 Query: 185 IVSYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDSDEETALRAAIESLYDAADDDS 244 + S D GG E+ Y + GSGS F L+ YS + + I ++ A DS Sbjct: 118 VFSIDAAGGSVEDI--YASTGSGSPFVYGVLESQYSEKMTVDEGVDLVIRAISAAKQRDS 175 Query: 245 ATGGPDLTRGIYPTAVTITQAGAVHVSEETTSELARRI 282 A+GG AV + G V + + R++ Sbjct: 176 ASGGMIDV------AVITRKDGYVQLPTDQIESRIRKL 207 >6EPF-6 nrPDB Length = 240 Score = 180 bits (456), Expect = 7e-46, Method: Composition-based stats. Identities = 47/218 (21%), Positives = 84/218 (38%), Gaps = 19/218 (8%) Query: 39 PENRIGHRSHSTRGGDGMESGDLAPHGTTIVALTYKGGVLLAGDRRATQGNLIASRDVEK 98 P+ + + G M A +G T++A+ + ++A D R ++G I +RD K Sbjct: 10 PDRELVMGPQGSAGPVQMRFSPYAFNGGTVLAIAGEDFSIVASDTRLSEGFSIHTRDSPK 69 Query: 99 VYVTDEYSAAGIAGTAGIAIELVRLFAVELEHYEKIEGVPLTFDGKANRLASMVRGNLGA 158 Y + + G +G G + L ++ L+ Y+ +T A L++++ Sbjct: 70 CYKLTDKTVIGCSGFHGDCLTLTKIIEARLKMYKHSNNKAMTTGAIAAMLSTILYSR--- 126 Query: 159 AMQGLAVVPLLVGYDLDADDESRAGRIVSYDVVGGRYEERAGYHAVGSGSLFAKSALKKI 218 P V ++ DE G + S+D VG +R + A GS S + L Sbjct: 127 -----RFFPYYVYNIIEGLDEEGKGAVYSFDPVGSY--QRDSFKAGGSASAMLQPLLDNQ 179 Query: 219 YSPD---------SDEETALRAAIESLYDAADDDSATG 247 + A+R + AA+ D TG Sbjct: 180 VGFKNMQNVEHVPLTLDRAMRLVKDVFISAAERDVYTG 217 >3H4P-a nrPDB Length = 219 Score = 177 bits (448), Expect = 6e-45, Method: Composition-based stats. Identities = 59/200 (29%), Positives = 94/200 (47%), Gaps = 9/200 (4%) Query: 66 TTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAGTAGIAIELVRLFA 125 TT V L V+LA D+RA+ GNL+A ++ +K+Y D+Y A IAG+ G A +VRL Sbjct: 2 TTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIVRLLI 61 Query: 126 VELEHYEKIEGVPLTFDGKANRLASMVRGNLGAAMQGLAVVPLLVGYDLDADDESRAGRI 185 E + Y+ G + A L++++ + + P L + D ++ Sbjct: 62 AEAKLYKMRTGRNIPPLACATLLSNILHSS--------RMFPFLTQIIIGGYDLLEGAKL 113 Query: 186 VSYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDSDEETALRAAIESLYDAADDDSA 245 S D +GG EE+ + A GSGS A L+ Y D E ++ A+ +L A + D+ Sbjct: 114 FSLDPLGGMNEEK-TFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERDTF 172 Query: 246 TGGPDLTRGIYPTAVTITQA 265 +G I V I + Sbjct: 173 SGNGISLAVITKDGVKIFED 192 >5MPC-h nrPDB Length = 215 Score = 173 bits (438), Expect = 8e-44, Method: Composition-based stats. Identities = 52/203 (25%), Positives = 82/203 (40%), Gaps = 19/203 (9%) Query: 65 GTTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAGTAGIAIELVRLF 124 GT+I+A+T+K GV+L D R T G IA+R +K+ + +G+A + + Sbjct: 19 GTSIMAVTFKDGVILGADSRTTTGAYIANRVTDKLTRVHDKIWCCRSGSAADTQAIADIV 78 Query: 125 AVELEHYEKIEGVPLTFDGKANRLASMVRGNLGAAMQGLAVVPLLVGYDLDADDESRAGR 184 LE Y G P T + A+ + N G+ ++ GY D+ G Sbjct: 79 QYHLELYTSQYGTPST-ETAASVFKELCYENKDNLTAGI----IVAGY-----DDKNKGE 128 Query: 185 IVSYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDSDEETALRAAIESLYDAADDDS 244 + Y + G + Y GSGS F K + + +E + SL A D Sbjct: 129 V--YTIPLGGSVHKLPYAIAGSGSTFIYGYCDKNFRENMSKEETVDFIKHSLSQAIKWDG 186 Query: 245 ATGGPDLTRGIYPTAVTITQAGA 267 ++GG V +T AG Sbjct: 187 SSGGV-------IRMVVLTAAGV 202 >5FMG-I nrPDB Length = 229 Score = 169 bits (428), Expect = 1e-42, Method: Composition-based stats. Identities = 44/205 (21%), Positives = 78/205 (38%), Gaps = 19/205 (9%) Query: 66 TTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAGTAGIAIELVRLFA 125 TTI L + V+L D RAT+G ++A ++ K++ + AG AG +E L+ Sbjct: 1 TTICGLVCQNAVILGADTRATEGPIVADKNCSKLHYISKNIWCAGAGVAGD-LEHTTLW- 58 Query: 126 VELEHYEKIEGVPLTFDGKANRLASMVRGNLGAAMQGLAVVPLLVGYDLDADDESRAGRI 185 L+H ++ + + + S + L +L G D++ Sbjct: 59 --LQHNVELHRLNTNTQPRVSMCVSRLTQELFKYQGYKVCAIVLGGVDVNGPQ------- 109 Query: 186 VSYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDSDEETALRAAIESLYDAADDDSA 245 Y + + A+GSGSL A + L+ Y + E E++ +D Sbjct: 110 -LYGIHPHGSSCLLPFTALGSGSLNAMAVLEAKYRDNMTIEEGKNLVCEAICAGIFNDLG 168 Query: 246 TGGPDLTRGIYPTAVTITQAGAVHV 270 +GG IT+ H+ Sbjct: 169 SGGN-------VDICVITKDSYQHI 186 >6EPF-2 nrPDB Length = 277 Score = 168 bits (425), Expect = 3e-42, Method: Composition-based stats. Identities = 48/183 (26%), Positives = 79/183 (43%), Gaps = 12/183 (6%) Query: 65 GTTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAGTAGIAIELVRLF 124 GTTI + YK G++L D RAT+G ++A ++ K++ AGTA +L Sbjct: 43 GTTIAGVVYKDGIVLGADTRATEGMVVADKNCSKIHFISPNIYCCGAGTAADTDMTTQLI 102 Query: 125 AVELEHYEKIEGVPLTFDGKANRLASMVRGNLGAAMQGLAVVPLLVGYDLDADDESRAGR 184 + LE + G L ANR M++ L + +L G D+ Sbjct: 103 SSNLELHSLTTG-RLPRVVTANR---MLKQMLFRYQGYIGAALVLGGVDVTGPH------ 152 Query: 185 IVSYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDSDEETALRAAIESLYDAADDDS 244 Y + ++ Y +GSGSL A + + + PD +EE A + E++ +D Sbjct: 153 --LYSIYPHGSTDKLPYVTMGSGSLAAMAVFEDKFRPDMEEEEAKKLVSEAIAAGIFNDL 210 Query: 245 ATG 247 +G Sbjct: 211 GSG 213 >5GJQ-a nrPDB Length = 239 Score = 168 bits (425), Expect = 3e-42, Method: Composition-based stats. Identities = 45/196 (22%), Positives = 76/196 (38%), Gaps = 11/196 (5%) Query: 65 GTTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAGTAGIAIELVRLF 124 GTTI+A+ + GGV+L D R T G+ IA+R +K+ + +G+A + Sbjct: 34 GTTIMAVQFDGGVVLGADSRTTTGSYIANRVTDKLTPIHDRIFCCRSGSAADTQAVADAV 93 Query: 125 AVELEHYEKIEGVPLTFDGKANRLASMVRGNLGAAMQGLAVVPLLVGYDLDADDESRAGR 184 +L + P A+ M + L ++ G+ D G+ Sbjct: 94 TYQLGFHSIELNEPPLVHTAASLFKEMCYR----YREDLMAGIIIAGW-----DPQEGGQ 144 Query: 185 IVSYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDSDEETALRAAIESLYDAADDDS 244 + Y V G R + GSGS + + Y +E L+ +L A + D Sbjct: 145 V--YSVPMGGMMVRQSFAIGGSGSSYIYGYVDATYREGMTKEECLQFTANALALAMERDG 202 Query: 245 ATGGPDLTRGIYPTAV 260 ++GG I + V Sbjct: 203 SSGGVIRLAAIAESGV 218 >6EPC-1 nrPDB Length = 238 Score = 168 bits (424), Expect = 4e-42, Method: Composition-based stats. Identities = 47/214 (21%), Positives = 82/214 (38%), Gaps = 11/214 (5%) Query: 65 GTTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAGTAGIAIELVRLF 124 GTTI+A+ + GGV+L D R T G+ IA+R +K+ ++ +G+A + Sbjct: 33 GTTIMAVQFDGGVVLGADSRTTTGSYIANRVTDKLTPIHDHIFCCRSGSAADTQAVADAV 92 Query: 125 AVELEHYEKIEGVPLTFDGKANRLASMVRGNLGAAMQGLAVVPLLVGYDLDADDESRAGR 184 +L + P A+ M + L ++ G+ D G+ Sbjct: 93 TYQLGFHSIELNEPPLVHTAASLFKEMCYR----YREDLMAGIIIAGW-----DPQEGGQ 143 Query: 185 IVSYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDSDEETALRAAIESLYDAADDDS 244 + Y V G R + GSGS + + Y ++ L+ +L A + D Sbjct: 144 V--YSVPMGGMMVRQSFAIGGSGSSYIYGYVDATYREGMTKDECLQFTANALALAMERDG 201 Query: 245 ATGGPDLTRGIYPTAVTITQAGAVHVSEETTSEL 278 ++GG I + V + + T S L Sbjct: 202 SSGGVIRLAAIQQSGVERQVLLGDQIPKVTISTL 235 >5L4G-8 nrPDB Length = 277 Score = 167 bits (422), Expect = 6e-42, Method: Composition-based stats. Identities = 48/183 (26%), Positives = 78/183 (42%), Gaps = 12/183 (6%) Query: 65 GTTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAGTAGIAIELVRLF 124 GTTI + YK G++L D RAT+G ++A ++ K++ AGTA +L Sbjct: 43 GTTIAGVVYKDGIVLGADTRATEGMVVADKNCSKIHFISPNIYCCGAGTAADTDMTTQLI 102 Query: 125 AVELEHYEKIEGVPLTFDGKANRLASMVRGNLGAAMQGLAVVPLLVGYDLDADDESRAGR 184 + LE + G L ANR M++ L + +L G D+ Sbjct: 103 SSNLELHSLSTG-RLPRVVTANR---MLKQMLFRYQGYIGAALVLGGVDVTGPH------ 152 Query: 185 IVSYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDSDEETALRAAIESLYDAADDDS 244 Y + ++ Y +GSGSL A + + + PD +EE A E++ +D Sbjct: 153 --LYSIYPHGSTDKLPYVTMGSGSLAAMAVFEDKFRPDMEEEEAKNLVSEAIAAGIFNDL 210 Query: 245 ATG 247 +G Sbjct: 211 GSG 213 >6HEC-1 nrPDB Length = 202 Score = 167 bits (422), Expect = 7e-42, Method: Composition-based stats. Identities = 65/220 (29%), Positives = 99/220 (45%), Gaps = 19/220 (8%) Query: 66 TTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAGTAGIAIELVRLFA 125 TT V L K GV++A ++RAT GN IAS+ +K+Y + A AG+ G A L R+ Sbjct: 1 TTTVGLVCKDGVVMATEKRATMGNFIASKAAKKIYQIADRMAMTTAGSVGDAQFLARIIK 60 Query: 126 VELEHYEKIEGVPLTFDGKANRLASMVRGNLGAAMQGLAVVPLLVGYDLDADDESRAGRI 185 +E YE T A ++++ P LV + D S I Sbjct: 61 IEANLYEIRRERKPTVRAIATLTSNLLNSYRY--------FPYLVQLLIGGID-SEGKSI 111 Query: 186 VSYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDSDEETALRAAIESLYDAADDDSA 245 S D +GG EE+ A GSGSL A L+ ++P+ + A+ A+ ++Y A DSA Sbjct: 112 YSIDPIGGAIEEKD-IVATGSGSLTAYGVLEDRFTPEIGVDEAVELAVRAIYSAMKRDSA 170 Query: 246 TG-GPDLTRGIYPTAVTITQAGAVHVSEETTSELARRIVA 284 +G G D+ + IT+ S E ++ + Sbjct: 171 SGDGIDVVK--------ITEDEFYQYSPEEVEQILAKFRK 202 >6HUB-H nrPDB Length = 234 Score = 166 bits (421), Expect = 7e-42, Method: Composition-based stats. Identities = 48/183 (26%), Positives = 78/183 (42%), Gaps = 12/183 (6%) Query: 66 TTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAGTAGIAIELVRLFA 125 TTI + YK G++L D RAT+G ++A ++ K++ AGTA +L + Sbjct: 1 TTIAGVVYKDGIVLGADTRATEGMVVADKNCSKIHFISPNIYCCGAGTAADTDMTTQLIS 60 Query: 126 VELEHYEKIEGVPLTFDGKANRLASMVRGNLGAAMQGLAVVPLLVGYDLDADDESRAGRI 185 LE + G L ANR M++ L + +L G D+ Sbjct: 61 SNLELHSLSTG-RLPRVVTANR---MLKQMLFRYQGYIGAALVLGGVDVTGPH------- 109 Query: 186 VSYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDSDEETALRAAIESLYDAADDDSA 245 Y + ++ Y +GSGSL A + + + PD +EE A E++ +D Sbjct: 110 -LYSIYPHGSTDKLPYVTMGSGSLAAMAVFEDKFRPDMEEEEAKNLVSEAIAAGIFNDLG 168 Query: 246 TGG 248 +GG Sbjct: 169 SGG 171 >5VFT-S nrPDB Length = 213 Score = 166 bits (419), Expect = 2e-41, Method: Composition-based stats. Identities = 44/200 (22%), Positives = 76/200 (38%), Gaps = 19/200 (9%) Query: 57 ESGDLAPHGTTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAGTAGI 116 +G TI+A+ + ++A D R ++G I +RD K Y + + G +G G Sbjct: 1 RFSPYVFNGGTILAIAGEDFAIVASDTRLSEGFSIHTRDSPKCYKLTDKTVIGCSGFHGD 60 Query: 117 AIELVRLFAVELEHYEKIEGVPLTFDGKANRLASMVRGNLGAAMQGLAVVPLLVGYDLDA 176 + L ++ L+ Y+ +T A L++++ P V + Sbjct: 61 CLTLTKIIEARLKMYKHSNNKAMTTGAIAAMLSTILYSR--------RFFPYYVYNIIGG 112 Query: 177 DDESRAGRIVSYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPD---------SDEET 227 DE G + S+D VG +R + A GS S + L + Sbjct: 113 LDEEGKGAVYSFDPVGSY--QRDSFKAGGSASAMLQPLLDNQVGFKNMQNVEHVPLSLDR 170 Query: 228 ALRAAIESLYDAADDDSATG 247 A+R + AA+ D TG Sbjct: 171 AMRLVKDVFISAAERDVYTG 190 >5LEZ-N nrPDB Length = 205 Score = 165 bits (417), Expect = 2e-41, Method: Composition-based stats. Identities = 44/195 (22%), Positives = 75/195 (38%), Gaps = 11/195 (5%) Query: 66 TTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAGTAGIAIELVRLFA 125 TTI+A+ + GGV+L D R T G+ IA+R +K+ + +G+A + Sbjct: 1 TTIMAVQFDGGVVLGADSRTTTGSYIANRVTDKLTPIHDRIFCCRSGSAADTQAVADAVT 60 Query: 126 VELEHYEKIEGVPLTFDGKANRLASMVRGNLGAAMQGLAVVPLLVGYDLDADDESRAGRI 185 +L + P A+ M + L ++ G+ D G++ Sbjct: 61 YQLGFHSIELNEPPLVHTAASLFKEMCYR----YREDLMAGIIIAGW-----DPQEGGQV 111 Query: 186 VSYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDSDEETALRAAIESLYDAADDDSA 245 Y V G R + GSGS + + Y +E L+ +L A + D + Sbjct: 112 --YSVPMGGMMVRQSFAIGGSGSSYIYGYVDATYREGMTKEECLQFTANALALAMERDGS 169 Query: 246 TGGPDLTRGIYPTAV 260 +GG I + V Sbjct: 170 SGGVIRLAAIAESGV 184 >5FGI-H nrPDB Length = 244 Score = 164 bits (415), Expect = 4e-41, Method: Composition-based stats. Identities = 39/184 (21%), Positives = 76/184 (41%), Gaps = 14/184 (7%) Query: 65 GTTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAGTAGIAIELVRLF 124 G TIV + + GV++A D R+TQG ++A ++ K++ AGTA + +L Sbjct: 12 GATIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEAVTQLI 71 Query: 125 AVELEHYEK-IEGVPLTFDGKANRLASMVRGNLGAAMQGLAVVPLLVGYDLDADDESRAG 183 +E + P M++ +L + ++ G D Sbjct: 72 GSNIELHSLYTSREPRVVSAL-----QMLKQHLFKYQGHIGAYLIVAGVDPTGSH----- 121 Query: 184 RIVSYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDSDEETALRAAIESLYDAADDD 243 + + + Y ++GSGSL A + L+ + D +E A++ A +++ +D Sbjct: 122 ---LFSIHAHGSTDVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWND 178 Query: 244 SATG 247 +G Sbjct: 179 LGSG 182 >6HV7-H nrPDB Length = 226 Score = 163 bits (413), Expect = 6e-41, Method: Composition-based stats. Identities = 39/183 (21%), Positives = 74/183 (40%), Gaps = 14/183 (7%) Query: 66 TTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAGTAGIAIELVRLFA 125 TTI L ++ GV+L D RAT +++A + EK++ AG A A + +L Sbjct: 1 TTIAGLVFQDGVILGADTRATNDSVVADKSCEKIHFIAPKIYCCGAGVAADAEAVTQLIG 60 Query: 126 VELEHYEK-IEGVPLTFDGKANRLASMVRGNLGAAMQGLAVVPLLVGYDLDADDESRAGR 184 +E + P M++ +L + ++ G D Sbjct: 61 SNIELHSLYTSREPRVVSAL-----QMLKQHLFKYQGHIGAYLIVAGVDPTGSH------ 109 Query: 185 IVSYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDSDEETALRAAIESLYDAADDDS 244 + + + Y ++GSGSL A + L+ + D +E A++ A +++ +D Sbjct: 110 --LFSIHAHGSTDVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDL 167 Query: 245 ATG 247 +G Sbjct: 168 GSG 170 >6AVO-A nrPDB Length = 199 Score = 163 bits (413), Expect = 7e-41, Method: Composition-based stats. Identities = 49/204 (24%), Positives = 83/204 (40%), Gaps = 19/204 (9%) Query: 66 TTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAGTAGIAIELVRLFA 125 TTI+A+ + GGV++ D R + G + +R +K+ E ++G+A A + + A Sbjct: 1 TTIMAVEFDGGVVMGSDSRVSAGEAVVNRVFDKLSPLHERIYCALSGSAADAQAVADMAA 60 Query: 126 VELEHYEKIEGVPLTFDGKANRLASMVRGNLGAAMQGLAVVPLLVGYDLDADDESRAGRI 185 +LE + P A++VR + L+ ++ G+ D+ G++ Sbjct: 61 YQLELHGIELEEPPLVLAA----ANVVRNISYKYREDLSAHLMVAGW-----DQREGGQV 111 Query: 186 VSYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDSDEETALRAAIESLYDAADDDSA 245 G R + GSGS F + Y P E R +++ A D + Sbjct: 112 YGT---LGGMLTRQPFAIGGSGSTFIYGYVDAAYKPGMSPEECRRFTTDAIALAMSRDGS 168 Query: 246 TGGPDLTRGIYPTAVTITQAGAVH 269 +GG VTIT AG H Sbjct: 169 SGGV-------IYLVTITAAGVDH 185 >6AVO-B nrPDB Length = 234 Score = 162 bits (409), Expect = 2e-40, Method: Composition-based stats. Identities = 43/183 (23%), Positives = 74/183 (40%), Gaps = 12/183 (6%) Query: 66 TTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAGTAGIAIELVRLFA 125 TTI L ++ GV+L D RAT +++A + EK++ AG A A R+ A Sbjct: 1 TTIAGLVFQDGVILGADTRATNDSVVADKSCEKIHFIAPKIYCCGAGVAADAEMTTRMVA 60 Query: 126 VELEHYEKIEGVPLTFDGKANRLASMVRGNLGAAMQGLAVVPLLVGYDLDADDESRAGRI 185 ++E + G + + + ++R L + ++ G DL Sbjct: 61 SKMELHALSTGR----EPRVATVTRILRQTLFRYQGHVGASLIVGGVDLTGPQ------- 109 Query: 186 VSYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDSDEETALRAAIESLYDAADDDSA 245 Y V R + A+GSG A + L+ + P+ E A +E++ D Sbjct: 110 -LYGVHPHGSYSRLPFTALGSGQDAALAVLEDRFQPNMTLEAAQGLLVEAVTAGILGDLG 168 Query: 246 TGG 248 +GG Sbjct: 169 SGG 171 >3UNH-H nrPDB Length = 234 Score = 160 bits (405), Expect = 5e-40, Method: Composition-based stats. Identities = 47/202 (23%), Positives = 80/202 (39%), Gaps = 19/202 (9%) Query: 66 TTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAGTAGIAIELVRLFA 125 TTI L ++ GV+L D RAT +++A + EK++ AG A R+ A Sbjct: 1 TTIAGLVFRDGVILGADTRATNDSVVADKSCEKIHFIAPKIYCCGAGVAADTEMTTRMAA 60 Query: 126 VELEHYEKIEGVPLTFDGKANRLASMVRGNLGAAMQGLAVVPLLVGYDLDADDESRAGRI 185 ++E + G + + + ++R L + ++ G DL+ Sbjct: 61 SKMELHALSTGR----EPRVATVTRILRQTLFRYQGHVGASLVVGGVDLNGPQ------- 109 Query: 186 VSYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDSDEETALRAAIESLYDAADDDSA 245 Y+V R + A+GSG A + L+ + P+ E A +E++ D Sbjct: 110 -LYEVHPHGSYSRLPFTALGSGQGAAVALLEDRFQPNMTLEAAQELLVEAITAGILSDLG 168 Query: 246 TGGPDLTRGIYPTAVTITQAGA 267 +GG A IT GA Sbjct: 169 SGGN-------VDACVITAGGA 183 >3UNF-N nrPDB Length = 199 Score = 154 bits (388), Expect = 5e-38, Method: Composition-based stats. Identities = 46/204 (22%), Positives = 82/204 (40%), Gaps = 19/204 (9%) Query: 66 TTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAGTAGIAIELVRLFA 125 TTI+A+ + GGV++ D R + G + +R +K+ + ++G+A A + + A Sbjct: 1 TTIMAVEFDGGVVVGSDSRVSAGTAVVNRVFDKLSPLHQRIFCALSGSAADAQAIADMAA 60 Query: 126 VELEHYEKIEGVPLTFDGKANRLASMVRGNLGAAMQGLAVVPLLVGYDLDADDESRAGRI 185 +LE + P AN + ++ + L ++ G+ D+ G++ Sbjct: 61 YQLELHGLELEEPPLVLAAANVVKNISY----KYREDLLAHLIVAGW-----DQREGGQV 111 Query: 186 VSYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDSDEETALRAAIESLYDAADDDSA 245 G R + GSGS + + Y P E R ++ A + D + Sbjct: 112 YGT---MGGMLIRQPFTIGGSGSSYIYGYVDAAYKPGMTPEECRRFTTNAITLAMNRDGS 168 Query: 246 TGGPDLTRGIYPTAVTITQAGAVH 269 +GG VTIT AG H Sbjct: 169 SGGV-------IYLVTITAAGVDH 185 >3H4P-A nrPDB Length = 264 Score = 149 bits (377), Expect = 1e-36, Method: Composition-based stats. Identities = 52/183 (28%), Positives = 83/183 (45%), Gaps = 8/183 (4%) Query: 60 DLAPHGTTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAGTAGIAIE 119 + GTT + + K GV+LA DRR T L+ R +EK++ D++ AA +G A Sbjct: 33 EAVRRGTTAIGIACKDGVVLAVDRRIT-SKLVKIRSIEKIFQIDDHVAAATSGLVADARV 91 Query: 120 LVRLFAVELEHYEKIEGVPLTFDGKANRLASMVRGNLGAAMQGLAVVPLLVGYDLDADDE 179 L+ +E + Y G ++ + A ++ + + A Q V P V + D+ Sbjct: 92 LIDRARLEAQIYRLTYGEEISIEMLAKKICDIKQ----AYTQHGGVRPFGVSLLIAGIDK 147 Query: 180 SRAGRIVSYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDSDEETALRAAIESLYDA 239 + A R+ D G E +A A+GSG L+K Y D + L AI +L A Sbjct: 148 NEA-RLFETDPSGALIEYKA--TAIGSGRPVVMELLEKEYRDDITLDEGLELAITALTKA 204 Query: 240 ADD 242 +D Sbjct: 205 NED 207 >5FMG-M nrPDB Length = 240 Score = 116 bits (289), Expect = 2e-26, Method: Composition-based stats. Identities = 41/207 (19%), Positives = 67/207 (32%), Gaps = 18/207 (8%) Query: 57 ESGDLAPHGTTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAGTAGI 116 +G T++ LT K V+LA D R + I +R K+ + G +G Sbjct: 29 RWYPYIDNGGTVIGLTGKDYVILAADTRLSLSYSIYTRFCPKISKLTDKCIIGSSGMQSD 88 Query: 117 AIELVRLFAVELEHYEKIEGVPLTFDGKANRLASMVRGNLGAAMQGLAVVPLLVGYDLDA 176 L L +++ + A L ++ P L Sbjct: 89 IKTLHSLLQKKIQLFVLEHSHYPDIHVIARLLCVILYSR--------RFFPYYAFNILAG 140 Query: 177 DDESRAGRIVSYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSP--------DSDEETA 228 DE+ G + +YD VG A + VGSGS L + + Sbjct: 141 VDENNKGVLYNYDSVGSY--CEATHSCVGSGSQLILPILDNRVEQKNQLIKNTNFNLGDD 198 Query: 229 LRAAIESLYDAADDDSATGGPDLTRGI 255 + +++ A + D TG L I Sbjct: 199 INFVKDAITSATERDIYTGDKTLIYVI 225 >6HE5-A nrPDB Length = 247 Score = 109 bits (272), Expect = 1e-24, Method: Composition-based stats. Identities = 45/215 (20%), Positives = 78/215 (36%), Gaps = 13/215 (6%) Query: 32 GHAPELLPENRIGHRSHSTRGGD-GMESG-DLAPHGTTIVALTYKGGVLLAGDRRATQGN 89 GH P++ S G +E + G T + + K GV+L D+R Sbjct: 2 GHLPQM--GYDRAITVFSPDGRLFQVEYAREAVKRGATAIGIKCKEGVILIADKRVGSKL 59 Query: 90 LIASRDVEKVYVTDEYSAAGIAGTAGIAIELVRLFAVELEHYEKIEGVPLTFDGKANRLA 149 L A +EK+Y DE+ A +G A L+ +E + P+T A ++ Sbjct: 60 LEAD-TIEKIYKIDEHICAATSGLVADARVLIDRARIEAQINRLTYDEPITVKELAKKIC 118 Query: 150 SMVRGNLGAAMQGLAVVPLLVGYDLDADDESRAGRIVSYDVVGGRYEERAGYHAVGSGSL 209 + Q V P V + D ++ D G E +A A+G G Sbjct: 119 DFKQQ----YTQYGGVRPFGVSLLIAGVD--EVPKLYETDPSGALLEYKA--TAIGMGRN 170 Query: 210 FAKSALKKIYSPDSDEETALRAAIESLYDAADDDS 244 +K Y D + A+ + ++ + + + Sbjct: 171 AVTEFFEKEYRDDLSFDDAMVLGLVAMGLSIESEL 205 >5FMG-E nrPDB Length = 256 Score = 104 bits (260), Expect = 4e-23, Method: Composition-based stats. Identities = 40/190 (21%), Positives = 72/190 (37%), Gaps = 7/190 (3%) Query: 65 GTTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAGTAGIAIELVRLF 124 G+T V + GV+LA +RR + LI VEK+ D++ ++G A L+ Sbjct: 34 GSTAVGICVNDGVILASERRIS-STLIEKDSVEKLLSIDDHIGCAMSGLMADARTLIDYA 92 Query: 125 AVELEHYEKIEGVPLTFDGKANRLASMV---RGNLGAAMQGLAVVPLLVGYDLDADDESR 181 VE HY+ I + ++ + + + + P V + D Sbjct: 93 RVECNHYKFIYNENINIKSCVELISELALDFSNLSDSKRKKIMSRPFGVALLIGGVD-KN 151 Query: 182 AGRIVSYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDSDEETALRAAIESLYDAAD 241 + + G R ++GS A+ L++ Y D E A A+ L + Sbjct: 152 GPCLWYTEPSGT--NTRFSAASIGSAQEGAELLLQENYKKDMTFEQAEILALTVLRQVME 209 Query: 242 DDSATGGPDL 251 D +T ++ Sbjct: 210 DKLSTSNVEI 219 >3NZW-L nrPDB Length = 241 Score = 104 bits (259), Expect = 4e-23, Method: Composition-based stats. Identities = 46/240 (19%), Positives = 75/240 (31%), Gaps = 33/240 (13%) Query: 45 HRSHSTRGGDGMESGDLAPHGTTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDE 104 + S ++ + +G TI+ + + +LAGD R I SR KV+ + Sbjct: 8 YSSEASNTPIEHQFNPYGDNGGTILGIAGEDFAVLAGDTRNITDYSINSRYEPKVFDCGD 67 Query: 105 YSAAGIAGTAGIAIELVRLFAVELEHYEKIEGVPLTFDGKANRLASMVRGNLGAAMQGLA 164 G A LV+ F ++ Y A R N+ + G Sbjct: 68 NIVMSANGFAADGDALVKRFKNSVKWYHFDHNDKKLSINSAAR-------NIQHLLYGKR 120 Query: 165 VVPLLVGYDLDADDESRAGRIVSYDVVGGRYEERAGYHAVGSGSLFAKSALK------KI 218 P V + DE G + S+D VG ER A G+ + L Sbjct: 121 FFPYYVHTIIAGLDEDGKGAVYSFDPVGSY--EREQCRAGGAAASLIMPFLDNQVNFKNQ 178 Query: 219 YSPD-----------SDEETALRAAIESLYDAADDDSATGGPDLTRGIYPTAVTITQAGA 267 Y P E ++ +S A + + G + +T+ G Sbjct: 179 YEPGTNGKVKKPLKYLSVEEVIKLVRDSFTSATER-------HIQVGDGLEILIVTKDGV 231 >3UNE-I nrPDB Length = 205 Score = 104 bits (258), Expect = 6e-23, Method: Composition-based stats. Identities = 36/187 (19%), Positives = 74/187 (39%), Gaps = 8/187 (4%) Query: 61 LAPHGTTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAGTAGIAIEL 120 ++ +G ++A+ K V +A DRR + + D +K++ + G+AG A + Sbjct: 4 MSYNGGAVMAMKGKNCVAIAADRRFGIQAQMVTTDFQKIFPMGDRLYIGLAGLATDVQTV 63 Query: 121 VRLFAVELEHYEKIEGVPLTFDGKANRLASMVRGNLGAAMQGLAVVPLLVGYDLDADDES 180 + L YE EG + + +A+++ P++ G D Sbjct: 64 AQRLKFRLNLYELKEGRQIKPYTLMSMVANLLYE---KRFGPYYTEPVIAGLDPKTF--- 117 Query: 181 RAGRIVSYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDSDEETALRAAIESLYDAA 240 I S D++G + G+ S + ++ P+ D E +++ +A Sbjct: 118 -KPFICSLDLIGCPMVT-DDFVVSGTCSEQMYGMCESLWEPNMDPEHLFETISQAMLNAV 175 Query: 241 DDDSATG 247 D D+ +G Sbjct: 176 DRDAVSG 182 >5FMG-N nrPDB Length = 265 Score = 102 bits (254), Expect = 2e-22, Method: Composition-based stats. Identities = 43/244 (17%), Positives = 81/244 (33%), Gaps = 38/244 (15%) Query: 56 MESGDLAPHGTTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAGTAG 115 M G + GT+++A+ YK G+++A DR+A+ G+ ++VE+++ + + G +G Sbjct: 1 MTLGPVV-TGTSVIAIKYKHGIMIAADRKASYGSYAKFQNVERIFKINNKTVMGFSGELA 59 Query: 116 IAIELVRLFAVEL--EHYEKIEGVPLTFDGKANRLASMVRGNLGAAMQGLAVVPLLVGYD 173 A L L + EK + + S V + L ++ G + Sbjct: 60 DAQYLHELLTRKNINNLSEKKRKEDMYTPQHYHSYVSRVFYVRKNRIDPLFNNIIIAGIN 119 Query: 174 LDADDESRAGRIVSYD----------------------------VVGGRYEERAGYHAVG 205 D + ++ + V Y G Sbjct: 120 SQKYDNNDDNVLLYTNKNNDDEQNEYKNNEEYKEIHKDDLYIGFVDMHGTNFCDDYITTG 179 Query: 206 SGSLFAKSALKKIYSPDSDEETALRAAIESLYDAADDDSATGGPDLTRGIYPTAVTITQA 265 FA + L+ Y + EE A E L D+ + + V +T Sbjct: 180 YARYFALTLLRDHYKDNMTEEEARILINECLRILYFRDATS-------SNFIQIVKVTSK 232 Query: 266 GAVH 269 G + Sbjct: 233 GVEY 236 >6J30-C nrPDB Length = 258 Score = 99.5 bits (246), Expect = 2e-21, Method: Composition-based stats. Identities = 37/178 (20%), Positives = 75/178 (42%), Gaps = 6/178 (3%) Query: 64 HGTTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAGTAGIAIELVRL 123 H T + + G++LA +R+ T L EK+Y ++ A +AG A L+ Sbjct: 31 HAGTAIGIMASDGIVLAAERKVTSTLLEQDTSTEKLYKLNDKIAVAVAGLTADAEILINT 90 Query: 124 FAVELEHYEKIEGVPLTFDGKANRLASMVRGNLGAAMQGLAVVPLLVGYDLDADDESRAG 183 + ++Y K + + RL+ + +G Q + P V + D+ Sbjct: 91 ARIHAQNYLKTYNEDIPVEILVRRLSDIKQG----YTQHGGLRPFGVSFIYAGYDDRYGY 146 Query: 184 RIVSYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDSDEETALRAAIESLYDAAD 241 ++ + + G +A +VG+ + A++ L+ Y D + A+ A+++L D Sbjct: 147 QLYTSNPSGNYTGWKA--ISVGANTSAAQTLLQMDYKDDMKVDDAIELALKTLSKTTD 202 >5FMG-H nrPDB Length = 252 Score = 97.5 bits (241), Expect = 6e-21, Method: Composition-based stats. Identities = 33/239 (13%), Positives = 75/239 (31%), Gaps = 45/239 (18%) Query: 66 TTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAGTAGIAIELVRLFA 125 TTI+ + Y GV+LA D R + G I+++ K+ +E +G + + +++ + Sbjct: 1 TTIIGIIYDNGVMLACDSRTSSGTFISNKCSRKINRINENLYVCRSGASAHSQKIIEIIK 60 Query: 126 VELEHYEKIEGVPLTFDGKANRLASMVRG------------------------------- 154 + F Sbjct: 61 HYCVSMKNENRKKGRFHEGETIYDETTYDEEIDIDSINYLDYNNNNDNNLVTKNKYFYED 120 Query: 155 -------------NLGAAMQGLAVVPLLVGYDLDADDESRAGRIVSYDVVGGRYEERAGY 201 ++ + L D+ + ++ + ++ G E+ + Sbjct: 121 KFNDYNPLVENVAHITKKIIYTNNNFLSCALIFGGYDKIKKQQLYAVNLNGS-IIEKHDF 179 Query: 202 HAVGSGSLFAKSALKKIYSPDSDEETALRAAIESLYDAADDDSATGGPDLTRGIYPTAV 260 GSGS++ +S L+ Y ++ + + A +D+++GG I + V Sbjct: 180 AVSGSGSIYIQSYLQDKYKKFMTKKECFNLILNCVKYAMHNDNSSGGLIRIVNITKSFV 238 >2KU2-A nrPDB Length = 237 Score = 96.8 bits (239), Expect = 9e-21, Method: Composition-based stats. Identities = 43/182 (23%), Positives = 76/182 (41%), Gaps = 8/182 (4%) Query: 60 DLAPHGTTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAGTAGIAIE 119 + G+T + + + GVLL D++ + LI +EK+ + D+Y AA +G A Sbjct: 33 EAVKKGSTALGMKFANGVLLISDKKV-RSRLIEQNSIEKIQLIDDYVAAVTSGLVADARV 91 Query: 120 LVRLFAVELEHYEKIEGVPLTFDGKANRLASMVRGNLGAAMQGLAVVPLLVGYDLDADDE 179 LV + + + G + + R+A ++ Q V P V D Sbjct: 92 LVDFARISAQQEKVTYGSLVNIENLVKRVADQMQQ----YTQYGGVRPYGVSLIFAGID- 146 Query: 180 SRAGRIVSYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDSDEETALRAAIESLYDA 239 R+ D G E +A A+GSG S L++ Y + E+ A+ I++L + Sbjct: 147 QIGPRLFDCDPAGTINEYKA--TAIGSGKDAVVSFLEREYKENLPEKEAVTLGIKALKSS 204 Query: 240 AD 241 + Sbjct: 205 LE 206 >5FGE-J nrPDB Length = 198 Score = 92.5 bits (228), Expect = 2e-19, Method: Composition-based stats. Identities = 35/169 (20%), Positives = 61/169 (36%), Gaps = 13/169 (7%) Query: 68 IVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAGTAGIAIELVRLFAVE 127 I+ + + V+LA + T+G + +K ++ AG AG ++ Sbjct: 4 ILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQAN 63 Query: 128 LEHYEKIEGVPLTFDGKANRLASMVRGNLGAAMQGLAVVP---LLVGYDLDADDESRAGR 184 ++ Y E L+ ++S VR L +++ L+ GYD + Sbjct: 64 IQLYSIREDYELSPQA----VSSFVRQELAKSIRSRRPYQVNVLIGGYD----KKKNKPE 115 Query: 185 IVSYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDSDEETALRAAI 233 + D +G + E Y A G + S L Y PD E L Sbjct: 116 LYQIDYLGTKVE--LPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLK 162 >4Y8P-I nrPDB Length = 205 Score = 90.6 bits (223), Expect = 6e-19, Method: Composition-based stats. Identities = 42/190 (22%), Positives = 78/190 (41%), Gaps = 9/190 (4%) Query: 58 SGDLAPHGTTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAGTAGIA 117 S + +G +VA+T K V +A D R +L S EK++ + GI G A Sbjct: 2 SDPSSINGGIVVAMTGKDCVAIACDLRLGSQSLGVSNKFEKIFHYG-HVFLGITGLATDV 60 Query: 118 IELVRLFAVELEHYEKIEGVPLTFDGKANRLASMVRGNLGAAMQGLAVVPLLVGYDLDAD 177 L +F + Y+ E + + ++S + V P++ G + Sbjct: 61 TTLNEMFRYKTNLYKLKEERAIEPETFTQLVSSSLYERRF---GPYFVGPVVAGI----N 113 Query: 178 DESRAGRIVSYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDSDEETALRAAIESLY 237 +S I +D++G E + + G+ S + +Y P+ + E ++L Sbjct: 114 SKSGKPFIAGFDLIGCIDEAKD-FIVSGTASDQLFGMCESLYEPNLEPEDLFETISQALL 172 Query: 238 DAADDDSATG 247 +AAD D+ +G Sbjct: 173 NAADRDALSG 182 >3WXR-K nrPDB Length = 238 Score = 90.2 bits (222), Expect = 9e-19, Method: Composition-based stats. Identities = 35/169 (20%), Positives = 61/169 (36%), Gaps = 13/169 (7%) Query: 68 IVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAGTAGIAIELVRLFAVE 127 I+ + + V+LA + T+G + +K ++ AG AG ++ Sbjct: 4 ILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQAN 63 Query: 128 LEHYEKIEGVPLTFDGKANRLASMVRGNLGAAMQGLAVVP---LLVGYDLDADDESRAGR 184 ++ Y E L+ ++S VR L +++ L+ GYD + Sbjct: 64 IQLYSIREDYELSPQA----VSSFVRQELAKSIRSRRPYQVNVLIGGYD----KKKNKPE 115 Query: 185 IVSYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDSDEETALRAAI 233 + D +G + E Y A G + S L Y PD E L Sbjct: 116 LYQIDYLGTKVE--LPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLK 162 >5FMG-C nrPDB Length = 246 Score = 86.8 bits (213), Expect = 1e-17, Method: Composition-based stats. Identities = 33/165 (20%), Positives = 62/165 (37%), Gaps = 6/165 (3%) Query: 64 HGTTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAGTAGIAIELVRL 123 + + + L K GV+L D+ + + + EK+Y D++ G+AG A L+ Sbjct: 30 NASITIGLITKDGVILGADKVFISKLIDKANNYEKIYKIDKHIFCGVAGLNADANILIN- 88 Query: 124 FAVELEHYEKIEGVPLTFDGKANRLASMVRGNLGAAMQGLAVVPLLVGYDLDADDESRAG 183 + Y + ++L + + Q + P V + + D Sbjct: 89 ---QSRLYAQRYLYNYNEVQPVSQLVVQICDIKQSYTQYGGLRPYGVSFLIGGYDTKDGY 145 Query: 184 RIVSYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDSDEETA 228 ++ D G A A+G+ +L A S LK+ + D E Sbjct: 146 QLYHTDPSGNYSGWFA--TAIGTNNLTASSVLKQEWKNDMTLEEG 188 >5FMG-J nrPDB Length = 218 Score = 85.6 bits (210), Expect = 2e-17, Method: Composition-based stats. Identities = 39/198 (19%), Positives = 73/198 (36%), Gaps = 12/198 (6%) Query: 58 SGDLAPHGTTIVALTYKGGVLLAGDRRATQGNLI-ASRDVEKVYVTDEYSAAGIAGTAGI 116 +G ++ ++ V +A D R S K++ + G++G A Sbjct: 2 GSIYNYNGGCVLGMSGSNCVAIACDLRLGANTFTTVSTKFSKIFKMNNNVYVGLSGLATD 61 Query: 117 AIELVRLFAVELEHYEKIEGVPLTFDGKANRLASMVRGNLGAAMQGLAVVPLLVGYDLDA 176 L + + YE + + + AN L+S++ N + V P++VG+ L Sbjct: 62 IQTLYEILRYRVNLYEVRQDAEMDVECFANMLSSILYSNRFSPYF---VNPIVVGFKLKH 118 Query: 177 DDESRA-------GRIVSYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDSDEETAL 229 + + +YD++G + E R + G S + +Y D DE Sbjct: 119 YVDEEGEKKVNYEPYLTAYDLIGAKCETRD-FVVNGVTSEQLFGMCESLYVKDQDENGLF 177 Query: 230 RAAIESLYDAADDDSATG 247 + L A D D +G Sbjct: 178 ETISQCLLSALDRDCISG 195 >5LEZ-C nrPDB Length = 248 Score = 84.8 bits (208), Expect = 4e-17, Method: Composition-based stats. Identities = 38/199 (19%), Positives = 83/199 (41%), Gaps = 15/199 (7%) Query: 60 DLAPHGTTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAGTAGIAIE 119 + G+T V + + V+L +++ + L R V K+ D+ AG A Sbjct: 24 EAVKKGSTAVGVRGRDIVVLGVEKK-SVAKLQDERTVRKICALDDNVCMAFAGLTADARI 82 Query: 120 LVRLFAVELEHYEKIEGVPLTFDGKANRLASMVRGNL-GAAMQGLAVVPLLVGYDLDADD 178 ++ VE + + P+T + +AS+ + + + L+VG+D D Sbjct: 83 VINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSNGRRPFGISALIVGFDFDG-- 140 Query: 179 ESRAGRIVSYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDS--DEETALRAAIESL 236 R+ D G + +A A+G G+ + L+K Y+ ++ ++ ++ I++L Sbjct: 141 ---TPRLYQTDPSGTYHAWKAN--AIGRGAKSVREFLEKNYTDEAIETDDLTIKLVIKAL 195 Query: 237 YDAADDDSATGGPDLTRGI 255 + +GG ++ + Sbjct: 196 LEVVQ----SGGKNIELAV 210 >5LE5-B nrPDB Length = 261 Score = 84.1 bits (206), Expect = 7e-17, Method: Composition-based stats. Identities = 43/179 (24%), Positives = 65/179 (36%), Gaps = 7/179 (3%) Query: 64 HGTTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAGTAGIAIELVRL 123 H T + + GVLLA +RR L EK+Y +E A +AG A L Sbjct: 30 HAGTCLGILANDGVLLAAERRNIHKLLDEVFFSEKIYKLNEDMACSVAGITSDANVLTNE 89 Query: 124 FAVELEHYEKIEGVPLTFDGKANRLASMVRGNLGAAMQGLAVVPLLVGYDLDADDESRAG 183 + + Y P+ + L + + A Q P V D+ Sbjct: 90 LRLIAQRYLLQYQEPIPCEQLVTALCDIKQ----AYTQFGGKRPFGVSLLYIGWDKHYGF 145 Query: 184 RIVSYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPD-SDEETALRAAIESLYDAAD 241 ++ D G +A +G+ S A S LK+ Y ++AL AI+ L D Sbjct: 146 QLYQSDPSGNYGGWKA--TCIGNNSAAAVSMLKQDYKEGEMTLKSALALAIKVLNKTMD 202 >5GJR-F nrPDB Length = 241 Score = 84.1 bits (206), Expect = 7e-17, Method: Composition-based stats. Identities = 37/183 (20%), Positives = 77/183 (42%), Gaps = 15/183 (8%) Query: 65 GTTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAGTAGIAIELVRLF 124 G+T + + GV LA ++R T L+ +EK+ D + ++G A L+ Sbjct: 34 GSTAIGIQTSEGVCLAVEKRIT-SPLMEPSSIEKIVEIDAHIGCAMSGLIADAKTLIDKA 92 Query: 125 AVELEHYEKIEGVPLTFDGKANRLASMVRG------NLGAAMQGLAVVPLLVGYDLDADD 178 VE +++ +T + ++++ + GA + V L G D Sbjct: 93 RVETQNHWFTYNETMTVESVTQAVSNLALQFGEEDADPGAMSRPFGVALLFGGVD----- 147 Query: 179 ESRAGRIVSYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDSDEETALRAAIESLYD 238 + ++ D G + A A+GS S A+S+L+++Y + A+++++ L Sbjct: 148 -EKGPQLFHMDPSGTFVQCDA--RAIGSASEGAQSSLQEVYHKSMTLKEAIKSSLIILKQ 204 Query: 239 AAD 241 + Sbjct: 205 VME 207 >2Z5C-C nrPDB Length = 262 Score = 83.7 bits (205), Expect = 8e-17, Method: Composition-based stats. Identities = 39/227 (17%), Positives = 79/227 (34%), Gaps = 12/227 (5%) Query: 65 GTTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAGTAGIAIELVRLF 124 G+T + + K GV+L ++RAT L+ S +EK+ D + ++G A ++ Sbjct: 36 GSTAIGIATKEGVVLGVEKRAT-SPLLESDSIEKIVEIDRHIGCAMSGLTADARSMIEHA 94 Query: 125 AVELEHYEKIEGVPLTFDGKANRLASMV--RGNLGAAMQGLAVVPLLVGYDLDADDESRA 182 + + + + + G + + L P V + D Sbjct: 95 RTAAVTHNLYYDEDINVESLTQSVCDLALRFGEGASGEERLMSRPFGVALLIAGHDADDG 154 Query: 183 GRIVSYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDSDEETALRAAIESLYDAADD 242 ++ + G R A+GSGS A++ L + + A ++ L ++ Sbjct: 155 YQLFHAEPSGTF--YRYNAKAIGSGSEGAQAELLNEWHSSLTLKEAELLVLKILKQVMEE 212 Query: 243 DSATGGPDLTRGIYPTAVTITQAGAVHVSEETTSELARRIVAERTEQ 289 L+ Q G E T+EL + + + + Sbjct: 213 KLDENNAQLS-------CITKQDGFKIYDNEKTAELIKELKEKEAAE 252 >1G0U-D nrPDB Length = 241 Score = 81.4 bits (199), Expect = 4e-16, Method: Composition-based stats. Identities = 38/225 (16%), Positives = 76/225 (33%), Gaps = 17/225 (7%) Query: 65 GTTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAGTAGIAIELVRLF 124 G+T + + K GV+L ++RAT L+ S +EK+ D + ++G A ++ Sbjct: 34 GSTAIGIATKEGVVLGVEKRAT-SPLLESDSIEKIVEIDRHIGCAMSGLTADARSMIEHA 92 Query: 125 AVELEHYEKIEGVPLTFDGKANRLASMVRGNLGAAMQGLAVVPLLVGYDLDADDESRAGR 184 + + + + + A P V + D + Sbjct: 93 RTAAVTHNLYYDEDINVESLTQSVCDL-------AAAAAMSRPFGVALLIAGHDADDGYQ 145 Query: 185 IVSYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDSDEETALRAAIESLYDAADDDS 244 + + G R A+GSGS A++ L + + A ++ L ++ Sbjct: 146 LFHAEPSGTF--YRYNAKAIGSGSEGAQAELLNEWHSSLTLKEAELLVLKILKQVMEEKL 203 Query: 245 ATGGPDLTRGIYPTAVTITQAGAVHVSEETTSELARRIVAERTEQ 289 L+ Q G E T+EL + + + + Sbjct: 204 DENNAQLS-------CITKQDGFKIYDNEKTAELIKELKEKEAAE 241 >4YA5-C nrPDB Length = 254 Score = 79.4 bits (194), Expect = 2e-15, Method: Composition-based stats. Identities = 34/180 (18%), Positives = 58/180 (32%), Gaps = 8/180 (4%) Query: 60 DLAPHGTTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAGTAGIAIE 119 + GT V + K V+L +RR+T KV D + +G + Sbjct: 25 EAVKRGTCAVGVKGKNCVVLGCERRSTLKLQDTRITPSKVSKIDSHVVLSFSGLNADSRI 84 Query: 120 LVRLFAVELEHYEKIEGVPLTFDGKANRLASMVRGNLGAAMQGLAVVPLLVGYDLDADDE 179 L+ VE + + P+T + +A + + Q V P V + D Sbjct: 85 LIEKARVEAQSHRLTLEDPVTVEYLTRYVAGVQQR----YTQSGGVRPFGVSTLIAGFDP 140 Query: 180 SRAGRIVSYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYS---PDSDEETALRAAIESL 236 Y +G S + L+K Y P + E ++ + SL Sbjct: 141 RDDEP-KLYQTEPSGIYSSWSAQTIGRNSKTVREFLEKNYDRKEPPATVEECVKLTVRSL 199 >6FVW-g nrPDB Length = 245 Score = 78.7 bits (192), Expect = 3e-15, Method: Composition-based stats. Identities = 39/184 (21%), Positives = 75/184 (40%), Gaps = 13/184 (7%) Query: 64 HGTTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAGTAGIAIELVRL 123 +GTT + + GV+ A ++ T L+ ++V K+ V D + +G LV Sbjct: 30 NGTTSIGIKCNDGVVFAVEKLITSKLLVPQKNV-KIQVVDRHIGCVYSGLIPDGRHLVNR 88 Query: 124 FAVELEHYEKIEGVPLTFDGKANRLASMVRGN-LGAAMQGLAVVPLLVGYDLDADDESRA 182 E ++K+ P+ A+RL V+ + L +++ V + G D Sbjct: 89 GREEAASFKKLYKTPIPIPAFADRLGQYVQAHTLYNSVRPFGVSTIFGGVD------KNG 142 Query: 183 GRIVSYDVVGGRYEERAGYHAVGSGSLFAKSALKK---IYSPDSDEETALRAAIESLYDA 239 + + G + + A G G AK+ L+K + A++ A + +Y A Sbjct: 143 AHLYMLEPSGSYWGYKG--AATGKGRQSAKAELEKLVDHHPEGLSAREAVKQAAKIIYLA 200 Query: 240 ADDD 243 +D+ Sbjct: 201 HEDN 204 >5FGG-F nrPDB Length = 288 Score = 77.9 bits (190), Expect = 5e-15, Method: Composition-based stats. Identities = 39/187 (20%), Positives = 75/187 (40%), Gaps = 13/187 (6%) Query: 61 LAPHGTTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAGTAGIAIEL 120 +GTT + + GV+ A ++ T L+ ++V K+ V D + +G L Sbjct: 30 AVENGTTSIGIKCNDGVVFAVEKLITSKLLVPQKNV-KIQVVDRHIGCVYSGLIPDGRHL 88 Query: 121 VRLFAVELEHYEKIEGVPLTFDGKANRLASMVRGN-LGAAMQGLAVVPLLVGYDLDADDE 179 V E ++K+ P+ A+RL V+ + L +++ V + G D Sbjct: 89 VNRGREEAASFKKLYKTPIPIPAFADRLGQYVQAHTLYNSVRPFGVSTIFGGVD------ 142 Query: 180 SRAGRIVSYDVVGGRYEERAGYHAVGSGSLFAKSALKK---IYSPDSDEETALRAAIESL 236 + + G + + A G G AK+ L+K + A++ A + + Sbjct: 143 KNGAHLYMLEPSGSYWGYKG--AATGKGRQSAKAELEKLVDHHPEGLSAREAVKQAAKII 200 Query: 237 YDAADDD 243 Y A +D+ Sbjct: 201 YLAHEDN 207 >5JI2-A nrPDB Length = 184 Score = 76.7 bits (187), Expect = 1e-14, Method: Composition-based stats. Identities = 44/176 (25%), Positives = 71/176 (40%), Gaps = 23/176 (13%) Query: 66 TTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVT-DEYSAAGIAGTAGIAIELVRLF 124 TTIV++ G V++AGD +AT GN + +V+KV ++ AG AG A L LF Sbjct: 2 TTIVSVRRNGHVVIAGDGQATLGNTVMKGNVKKVRRLYNDKVIAGFAGGTADAFTLFELF 61 Query: 125 AVELEHYEKIEGVPLTFDGKANRLASMVRG-NLGAAMQGLAVVPLLVGYDLDADDESRAG 183 +LE ++ K R M+R A+ ++ G Sbjct: 62 ERKLEMHQGHLVKAAVELAKDWRTDRMLRKLEALLAVADETASLIITGN----------- 110 Query: 184 RIVSYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDSDEETALRAAIESLYDA 239 G + A+GSG +A++A + + E +A A ++L A Sbjct: 111 --------GDVVQPENDLIAIGSGGPYAQAAARALLEN--TELSAREIAEKALDIA 156 >5FMG-D nrPDB Length = 241 Score = 74.4 bits (181), Expect = 6e-14, Method: Composition-based stats. Identities = 38/229 (16%), Positives = 86/229 (37%), Gaps = 17/229 (7%) Query: 60 DLAPHGTTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAGTAGIAIE 119 + G VA+ +LA +++ L + EK+ DE++ AG A Sbjct: 24 EAVKKGGCAVAIKSSNFAVLAVEKK-NIPKLQNPKTTEKLIKLDEHNCLAFAGLNADARV 82 Query: 120 LVRLFAVELEHYEKIEGVPLTFDGKANRLASMVRGNLGAAMQGLAVVPLLVGYDLDADDE 179 LV +E + Y P D A +A + + V P + + Sbjct: 83 LVNKTRLECQRYYLNMDEPAPVDYIAKYVAKVQQ----KFTHRGGVRPFGIATLIAGFKN 138 Query: 180 SRAGRIVSYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDSDEETALRAAIESLYDA 239 ++ I + G +A A+G + + L+K Y + +++ + A++++++ Sbjct: 139 NKEICIYQTEPSGIYAAWKA--QAIGKNAKIVQEFLEKNYQENMEQKDCIFLALKAIFEV 196 Query: 240 ADDDSATGGPDLTRGIYPTAVTITQAGAVHVSEETTSELARRIVAERTE 288 + ++ ++ +T+ + E+ + + I ERT+ Sbjct: 197 VE--LSSKNVEVA--------LLTEKDLTFIEEQEINSMVELIDQERTK 235 >4FZC-A nrPDB Length = 250 Score = 74.0 bits (180), Expect = 6e-14, Method: Composition-based stats. Identities = 40/183 (21%), Positives = 80/183 (43%), Gaps = 10/183 (5%) Query: 61 LAPHGTTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAGTAGIAIEL 120 G T + + GV++A +++++ L S + KV + A +G L Sbjct: 27 AVKQGVTSLGIKATNGVVIATEKKSS-SPLAMSETLSKVSLLTPDIGAVYSGMGPDYRVL 85 Query: 121 VRLFAVELEH--YEKIEGVPLTFDGKANRLASMVRGNLGAAMQGLAVVPLLVGYDLDADD 178 V + ++ H Y++I G + +A +++ A Q V P V + D Sbjct: 86 VDK-SRKVAHTSYKRIYGEYPPTKLLVSEVAKIMQE----ATQSGGVRPFGVSLLIAGHD 140 Query: 179 ESRAGRIVSYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDSDEETALRAAIESLYD 238 E + D G + +A A+G GS+ AK+ L+K ++ + + E A+ A+ +L + Sbjct: 141 EFNGFSLYQVDPSGSYFPWKA--TAIGKGSVAAKTFLEKRWNDELELEDAIHIALLTLKE 198 Query: 239 AAD 241 + + Sbjct: 199 SVE 201 >5LF3-J nrPDB Length = 201 Score = 73.7 bits (179), Expect = 9e-14, Method: Composition-based stats. Identities = 35/169 (20%), Positives = 60/169 (35%), Gaps = 8/169 (4%) Query: 68 IVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAGTAGIAIELVRLFAVE 127 ++ + VL+A DR A + D +K++ E G AG ++ Sbjct: 4 LIGIQGPDYVLVASDRVAASNIVQMKDDHDKMFKMSEKILLLCVGEAGDTVQFAEYIQKN 63 Query: 128 LEHYEKIEGVPLTFDGKANRLASMVRGNLGAAMQGLAVVPLLVGYDLDADDESRAGRIVS 187 ++ Y+ G L+ A+ R NL ++ P V L DE + Sbjct: 64 VQLYKMRNGYELSPTAA----ANFTRRNLADCLRSRT--PYHVNLLLAGYDEHEGPALYY 117 Query: 188 YDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDSDEETALRAAIESL 236 D + + H G G+ S L + Y+P E A+ + L Sbjct: 118 MDYLAALAKAPFAAH--GYGAFLTLSILDRYYTPTISRERAVELLRKCL 164 >5FMG-B nrPDB Length = 235 Score = 70.6 bits (171), Expect = 8e-13, Method: Composition-based stats. Identities = 35/166 (21%), Positives = 63/166 (37%), Gaps = 10/166 (6%) Query: 69 VALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAGTAGIAIELVRLFAVEL 128 + + K GV++A +++ + LI + K+ E+ AG G L++ E Sbjct: 36 LGIRAKNGVIIATEKK-SPNELIEENSIFKIQQISEHIGIVYAGMPGDFRVLLKRARKEA 94 Query: 129 EHYEKIEGVPLTFDGKANRLASMVRGNLGAA-MQGLAVVPLLVGYDLDADDESRAGRIVS 187 Y G + +AS+V+ ++ + L+ G D+ + Sbjct: 95 IRYSLQYGSEILVKELVKIIASIVQEFTQTGGVRPFGLSLLICGVDVYGYH------LYQ 148 Query: 188 YDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDSDEETALRAAI 233 D G + A VG S L+K Y+ D + E A+ AI Sbjct: 149 IDPSGCYFNWMA--TCVGKDYQNNMSFLEKRYNKDIEIEDAIHTAI 192 >6GOP-M nrPDB Length = 246 Score = 68.7 bits (166), Expect = 3e-12, Method: Composition-based stats. Identities = 36/192 (18%), Positives = 76/192 (39%), Gaps = 18/192 (9%) Query: 65 GTTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAGTAGIAIELVRLF 124 GT+++++ Y GV++A D + G+L+ VE++ + + GI+G + RL Sbjct: 21 GTSVISMKYDNGVIIAADNLGSYGSLLRFNGVERLIPVGDNTVVGISGDISDMQHIERLL 80 Query: 125 AVELEHYEKIEGVPLTFDGKANR-----LASMVRGNLGAAMQGLAVVPLLVGYDLDADDE 179 + + + LA+++ M L ++ G + D Sbjct: 81 KDLVTENAYDNPLADAEEALEPSYIFEYLATVMYQRRSK-MNPLWNAIIVAGVQSNGDQF 139 Query: 180 SRAGRIVSYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDSD-EETALRAAIESLYD 238 R ++ + A G G+ A L+K+ +SD +T ++ A E++ + Sbjct: 140 LRYVNLL-------GVTYSSPTLATGFGAHMANPLLRKVVDRESDIPKTTVQVAEEAIVN 192 Query: 239 AA----DDDSAT 246 A D+ + Sbjct: 193 AMRVLYYRDARS 204 >5LF0-A nrPDB Length = 234 Score = 68.3 bits (165), Expect = 4e-12, Method: Composition-based stats. Identities = 36/170 (21%), Positives = 68/170 (40%), Gaps = 10/170 (5%) Query: 65 GTTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAGTAGIAIELVRLF 124 G V + GV+LA +++ + L R V KV ++ +G LV Sbjct: 32 GAPSVGIKAANGVVLATEKK-QKSILYDERSVHKVEPITKHIGLVYSGMGPDYRVLVHRA 90 Query: 125 AVELEHYEKIEGVPLTFDGKANRLASMVRGNLGAA-MQGLAVVPLLVGYDLDADDESRAG 183 + Y + P+ R+AS+++ + ++ V L+ G++ Sbjct: 91 RKLAQQYYLVYQEPIPTAQLVQRVASVMQEYTQSGGVRPFGVSLLICGWN------EGRP 144 Query: 184 RIVSYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDSDEETALRAAI 233 + D G + +A A+G + K+ L+K Y+ D + E A+ AI Sbjct: 145 YLFQSDPSGAYFAWKA--TAMGKNYVNGKTFLEKRYNEDLELEDAIHTAI 192 >5GJQ-g nrPDB Length = 264 Score = 67.1 bits (162), Expect = 8e-12, Method: Composition-based stats. Identities = 33/210 (15%), Positives = 79/210 (37%), Gaps = 11/210 (5%) Query: 39 PENRIGHRSHSTRGGDGMESGDLAPHGTTIVALTYKGGVLLAGDRRATQGNLIASRDVEK 98 P++ + S RG + GT+++ + ++GGV++A D + G+L R++ + Sbjct: 28 PDSFMDPASALYRGPITRTQNPMV-TGTSVLGVKFEGGVVIAADMLGSYGSLARFRNISR 86 Query: 99 VYVTDEYSAAGIAGTAGIAIELVRLFAVELEHYEKIEGVPLTFDGKANRLASMVRGNLGA 158 + + + G +G L ++ ++ E++ G ++ +A Sbjct: 87 IMRVNNSTMLGASGDYADFQYLKQVLG-QMVIDEELLGDGHSYSPRAIHSWLTRAMYSRR 145 Query: 159 AMQGLAVVPLLVGYDLDADDESRAGRIVSYDVVGGRYEERAGYHAVGSGSLFAKSALKK- 217 + +++G D + + D++G A A G G+ A+ L++ Sbjct: 146 SKMNPLWNTMVIGGYADGE-----SFLGYVDMLG--VAYEAPSLATGYGAYLAQPLLREV 198 Query: 218 -IYSPDSDEETALRAAIESLYDAADDDSAT 246 P + A + D+ + Sbjct: 199 LEKQPVLSQTEARDLVERCMRVLYYRDARS 228 >5LF6-M nrPDB Length = 219 Score = 67.1 bits (162), Expect = 9e-12, Method: Composition-based stats. Identities = 29/184 (15%), Positives = 71/184 (38%), Gaps = 10/184 (5%) Query: 65 GTTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAGTAGIAIELVRLF 124 GT+++ + ++GGV++A D + G+L R++ ++ + + G +G L ++ Sbjct: 8 GTSVLGVKFEGGVVIAADMLGSYGSLARFRNISRIMRVNNSTMLGASGDYADFQYLKQVL 67 Query: 125 AVELEHYEKIEGVPLTFDGKANRLASMVRGNLGAAMQGLAVVPLLVGYDLDADDESRAGR 184 ++ E++ G ++ +A + +++G D + Sbjct: 68 G-QMVIDEELLGDGHSYSPRAIHSWLTRAMYSRRSKMNPLWNTMVIGGYADGE-----SF 121 Query: 185 IVSYDVVGGRYEERAGYHAVGSGSLFAKSALKK--IYSPDSDEETALRAAIESLYDAADD 242 + D++G A A G G+ A+ L++ P + A + Sbjct: 122 LGYVDMLG--VAYEAPSLATGYGAYLAQPLLREVLEKQPVLSQTEARDLVERCMRVLYYR 179 Query: 243 DSAT 246 D+ + Sbjct: 180 DARS 183 >1OFH-G nrPDB Length = 174 Score = 66.3 bits (160), Expect = 1e-11, Method: Composition-based stats. Identities = 22/68 (32%), Positives = 34/68 (50%), Gaps = 1/68 (1%) Query: 66 TTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVT-DEYSAAGIAGTAGIAIELVRLF 124 TTIV++ G V++ GD + + GN + + KV + AG AG A L LF Sbjct: 1 TTIVSVRRNGQVVVGGDGQVSLGNTVMKGNARKVRRLYNGKVLAGFAGGTADAFTLFELF 60 Query: 125 AVELEHYE 132 +LE ++ Sbjct: 61 ERKLEMHQ 68 >6EPE-7 nrPDB Length = 263 Score = 65.6 bits (158), Expect = 2e-11, Method: Composition-based stats. Identities = 31/186 (16%), Positives = 69/186 (37%), Gaps = 14/186 (7%) Query: 65 GTTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAGTAGIAIELVRLF 124 GT+++ + + GV++A D + G+L R++ ++ ++ + G +G L ++ Sbjct: 52 GTSVLGVKFDCGVVIAADMLGSYGSLARFRNISRIMRVNDSTMLGASGDYADFQYLKQVL 111 Query: 125 AVELEHYEKIEGVPLTFDGKANRLASMVRGNLGAAMQGLA--VVPLLVGYDLDADDESRA 182 ++ E++ G ++ +A + L AM + PL ++ Sbjct: 112 G-QMVIDEELFGDGHSYSPRA------IHSWLTRAMYSRRSKMNPL---WNTKVIGGYAG 161 Query: 183 GRIVSYDVVGGRYEERAGYHAVGSGSLFAKSALKK--IYSPDSDEETALRAAIESLYDAA 240 G V A A G G+ A+ L++ P + A + Sbjct: 162 GESFLGYVDMLGVAYEAPSLATGYGAYLAQPLLREVLEKQPVLSQTEARELVERCMRVLY 221 Query: 241 DDDSAT 246 D+ + Sbjct: 222 YRDARS 227 >5FMG-K nrPDB Length = 195 Score = 64.0 bits (154), Expect = 7e-11, Method: Composition-based stats. Identities = 30/167 (17%), Positives = 55/167 (32%), Gaps = 12/167 (7%) Query: 67 TIVALTYKGGVLLAGDRRATQGNLIASRDVE--KVYVTDEYSAAGIAGTAGIAIELVRLF 124 T++ L V+LA D + ++I ++ + K Y + G+ G ++ Sbjct: 3 TLIGLRGNNFVVLAADT-YSINSIIKLKNDDNTKFYDIHGNKCLLLGGSIGDRLQFGEFI 61 Query: 125 AVELEHYEKIEGVPLTFDGKANRLASMVRGNLGAAMQGLAVVPLLVGYDLDADDESRAGR 184 + Y+ + A R NL L P V + D+ + Sbjct: 62 RKNVHLYQYQNNTDMFVKS----FAFFTRKNLAYY---LRRNPFEVNCLIAGYDKKDGYQ 114 Query: 185 IVSYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDSDEETALRA 231 + D + G A G G+ + L K Y + + AL Sbjct: 115 LYWCDYLSNMDSVNKG--AHGYGAYLVSAILDKYYHENLTVDEALDI 159 >6EPD-G nrPDB Length = 255 Score = 62.9 bits (151), Expect = 1e-10, Method: Composition-based stats. Identities = 29/174 (16%), Positives = 64/174 (36%), Gaps = 7/174 (4%) Query: 64 HGTTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAGTAGIAIELVRL 123 + +T + + K GV+ + + L ++++ D + +AG A L + Sbjct: 33 NSSTAIGIRCKDGVVFGVE-KLVLSKLYEEGSNKRLFNVDRHVGMAVAGLLADARSLADI 91 Query: 124 FAVELEHYEKIEGVPLTFDGKANRLASMVRGNLGAAMQGLAVVPLLVGYDLDADDESRAG 183 E ++ G + A+R+A + A AV P + L + + Sbjct: 92 AREEASNFRSNFGYNIPLKHLADRVA----MYVHAYTLYSAVRPFGCSFMLGSYSVNDGA 147 Query: 184 RIVSYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDSDEETALRAAIESLY 237 ++ D G Y A+G AK+ ++K+ + ++ + +Y Sbjct: 148 QLYMIDPSGVSYGYWG--CAIGKARQAAKTEIEKLQMKEMTCRDVVKEVAKIIY 199 >3TY6-A nrPDB Length = 183 Score = 61.3 bits (147), Expect = 5e-10, Method: Composition-based stats. Identities = 49/181 (27%), Positives = 68/181 (37%), Gaps = 24/181 (13%) Query: 63 PHGTTIVALTYKGGVLLAGDRRATQGNLIA----SRDVEKVYVTDEYSAAGIAGTAGIAI 118 H TTI A+ + G +AGD + T GN + +R V K++ AG AG+ A Sbjct: 7 FHATTIFAVHHNGECAMAGDGQVTMGNAVVMKHTARKVRKLFQ--GKVLAGFAGSVADAF 64 Query: 119 ELVRLFAVELEHYEKIEGVPLTFDGKANRLASMVRGNLGAAMQGLAVVPLLVGYDLDADD 178 L +F +LE Y K R M+R + LLV Sbjct: 65 TLFEMFEGKLEEYNGNLQRAAVEMAKQWRGDKMLRQLEAMLIVMDKTTMLLV-------- 116 Query: 179 ESRAGRIVSYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDSDEETALRAAIESLYD 238 G E G A+GSG +A SA + + S+ TA + A SL Sbjct: 117 ----------SGTGEVIEPDDGILAIGSGGNYALSAGRALKQYASEHLTAKQIAKASLEI 166 Query: 239 A 239 A Sbjct: 167 A 167 >5FMG-F nrPDB Length = 254 Score = 60.6 bits (145), Expect = 7e-10, Method: Composition-based stats. Identities = 40/235 (17%), Positives = 83/235 (35%), Gaps = 22/235 (9%) Query: 59 GDLAPHGTTIVALTYKGGVLLAGDRRATQGNLIASRDV--EKVYVTDEYSAAGIAGTAGI 116 + GT VA+ K V+++G ++ I+ EK++ D+Y ++G Sbjct: 26 SEAIKQGTCAVAIKSKDYVVVSGLKKC-----ISKLSFPQEKIFKIDDYIGISMSGITSD 80 Query: 117 AIELVRLFAVELEHYEKIEGVPLTFDGKANRLASMVRGNLGAAMQGLAVVPLLVGYDLDA 176 A L + E ++ + + + +A + N Q + VG + A Sbjct: 81 AKVLTKFMQNECLSHKFLYNENINIESLVRSVADKYQKN----TQKSSKRAFGVGLMIAA 136 Query: 177 DDESRAGRIVSYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYS--PDSDEETALRAAIE 234 I G +E A + G+ S +K+ L+K + E + ++ Sbjct: 137 YHNE--PCIFETRPNGSYFEYDA--LSFGARSHASKTYLEKNLHLFEECSLEELILHCLK 192 Query: 235 SLYDAADDDSATGGPDLTRGIYPTAVTITQAGAVHVSEETTSELARRIVAERTEQ 289 +L + +S +LT AV +S E ++ + ++ Sbjct: 193 ALKCSLSSES-----ELTISNTALAVVGKNHPWQEISSLQLEEYLSKVKMDAEQE 242 >4HO7-A nrPDB Length = 179 Score = 59.4 bits (142), Expect = 2e-09, Method: Composition-based stats. Identities = 42/183 (22%), Positives = 70/183 (38%), Gaps = 22/183 (12%) Query: 66 TTIVALTYKGGVLLAGDRRATQGNLIASRDVE-KVYVTDEYSAAGIAGTAGIAIELVRLF 124 TTI+++ V+L GDR+ T G I ++ K+ ++ G AG+ AI L+ Sbjct: 1 TTILSVRKGDTVVLLGDRQVTLGERIVAKSSACKLRRINDDVVIGFAGSTADAISLMEKL 60 Query: 125 AVELEHYEKIEGVPLTFDGKANRLASMVRGNLGAAMQGLAVVPLLVGYDLDADDESRAGR 184 ++ + K R +R L ++ A Sbjct: 61 ENKIGEFPNQLTRAAVELAKEWRTDRALRR--------LEASLIVC----------SAEE 102 Query: 185 IVSYDVVGGRYE-ERAGYHAVGSGSLFAKSALKKIYSPDSDEETALRAAIESLYDAADDD 243 + D G E G A+GSG FAK+A + + D D A + A +++ A D D Sbjct: 103 TLEIDGQGNVITPEADGIVAIGSGGTFAKAAARALI--DVDGYDAEKIARKAMRIATDID 160 Query: 244 SAT 246 + Sbjct: 161 VFS 163 >5T0I-L nrPDB Length = 268 Score = 59.0 bits (141), Expect = 2e-09, Method: Composition-based stats. Identities = 45/208 (21%), Positives = 74/208 (35%), Gaps = 21/208 (10%) Query: 60 DLAPHGTTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAGTAGIAIE 119 + G+ V L K +L +RA Q L A + +K+ D + IAG A Sbjct: 32 EAVKQGSATVGLKSKTHAVLVALKRA-QSELAAHQ--KKILHVDNHIGISIAGLTADARL 88 Query: 120 LVRLFAVELEHYEKIEGVPLTFDGKANRLASMVRGNLGAAMQGLAVVPLLVGYDLDADDE 179 L E + PL +RL S++ Q P VG + D+ Sbjct: 89 LCNFMRQECLDSRFVFDRPLPV----SRLVSLIGSKTQIPTQRYGRRPYGVGLLIAGYDD 144 Query: 180 SRAGRIVSYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDS--DEETALRAAIESL- 236 I ++ RA ++G+ S A++ L++ S + ++ + +L Sbjct: 145 M-GPHIFQTCPSANYFDCRA--MSIGARSQSARTYLERHMSEFMECNLNELVKHGLRALR 201 Query: 237 -YDAADDDSATG-------GPDLTRGIY 256 A+ D T G DL IY Sbjct: 202 ETLPAEQDLTTKNVSIGIVGKDLEFTIY 229 >2Z3B-A nrPDB Length = 180 Score = 59.0 bits (141), Expect = 2e-09, Method: Composition-based stats. Identities = 44/178 (24%), Positives = 67/178 (37%), Gaps = 23/178 (12%) Query: 62 APHGTTIVALTYKGGVLLAGDRRATQG-NLIASRDVEKVYVT-DEYSAAGIAGTAGIAIE 119 + H TTI A+ +KG ++GD + T G ++ KV + AG AG+ A Sbjct: 2 SFHATTIFAVQHKGRSAMSGDGQVTFGQAVVMKHTARKVRKLFNGKVLAGFAGSVADAFT 61 Query: 120 LVRLFAVELEHYEKIEGVPLTFDGKANRLASMVRGNLGAAMQGLAVVPLLVGYDLDADDE 179 L F +LE Y K R ++R L + +++ D Sbjct: 62 LFEKFEAKLEEYNGNLKRAAVELAKEWRSDKVLRK--------LEAMLIVMNQDT----- 108 Query: 180 SRAGRIVSYDVVGGRYEERAGYHAVGSGSLFAKS---ALKKIYSPDSDEETALRAAIE 234 ++ G E G A+GSG +A + ALKK RAA+E Sbjct: 109 -----LLLVSGTGEVIEPDDGILAIGSGGNYALAAGRALKKHAGESMSASEIARAALE 161 >3NZW-E nrPDB Length = 234 Score = 58.3 bits (139), Expect = 4e-09, Method: Composition-based stats. Identities = 37/186 (19%), Positives = 69/186 (37%), Gaps = 16/186 (8%) Query: 64 HGTTIVALTYK-GGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAGTAGIAIELVR 122 G+ V L VL+A R A + + +K+ DE+ +AG A A L Sbjct: 31 QGSVTVGLRSNTHAVLVALKRNADELSSYQ----KKIIKCDEHMGLSLAGLAPDARVLSN 86 Query: 123 LFAVELEHYEKIEGVPLTFDGKANRLASMVRGNLGAAMQGLAVVPLLVGYDLDADDESRA 182 + + + L + + L + N Q P VG + D Sbjct: 87 YLRQQCNYSSLVFNRKLAVERAGHLLCDKAQKN----TQSYGGRPYGVGLLIIGYD-KSG 141 Query: 183 GRIVSYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSP----DSDEETALRAAIESLYD 238 ++ + G E A+G+ S AK+ L++ D + + ++A +E++ Sbjct: 142 AHLLEFQPSGNVTELYG--TAIGARSQGAKTYLERTLDTFIKIDGNPDELIKAGVEAISQ 199 Query: 239 AADDDS 244 + D+S Sbjct: 200 SLRDES 205 >5FMG-G nrPDB Length = 252 Score = 56.3 bits (134), Expect = 2e-08, Method: Composition-based stats. Identities = 25/168 (14%), Positives = 54/168 (32%), Gaps = 7/168 (4%) Query: 64 HGTTIVALTYKGGVLLA-GDRRATQGNLIASRDVEKVYVTDEYSAAGIAGTAGIAIELVR 122 + T + L K G++ + + +I ++Y + +G G A ++ Sbjct: 33 NNNTALCLECKDGIICCCINSNMDKNKMIKKNSYNRIYHVNNNIIITYSGFDGDARNIID 92 Query: 123 LFAVELEHYEKIEGVPLTFDGKANRLASMVRGNLGAAMQGLAVVPLLVGYDLDADDESRA 182 E Y + NR++ + A + P + + +E Sbjct: 93 RARSEANTYYYNFHTNIPLHILVNRISL----YIHAYTLYWHMRPFAASIIISSFNEKDK 148 Query: 183 GRIVSYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDSDEETALR 230 G I + G Y+ +G K+ ++K D + A+ Sbjct: 149 GDIYCIEPNGACYKYSG--IVIGKNKEMFKTEIEKKDYKDINVRDAIE 194 >1M4Y-A nrPDB Length = 171 Score = 54.8 bits (130), Expect = 5e-08, Method: Composition-based stats. Identities = 30/146 (20%), Positives = 49/146 (33%), Gaps = 19/146 (13%) Query: 66 TTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDE-YSAAGIAGTAGIAIELVRLF 124 TTI+ + G ++ GD + T G+ + + KV E AG AG+ A+ L F Sbjct: 1 TTILVVRRNGQTVMGGDGQVTFGSTVLKGNARKVRKLGEGKVLAGFAGSVADAMTLFDRF 60 Query: 125 AVELEHYEKIEGVPLTFDGKANRLASMVRGNLGAAMQGLAVVPLLVGYDLDADDESRAGR 184 +L + K R ++R L + L+ Sbjct: 61 EAKLREWGGNLTKAAVELAKDWRTDRVLRR--------LEALLLVA----------DKEN 102 Query: 185 IVSYDVVGGRYEERAGYHAVGSGSLF 210 I G + A+GSG + Sbjct: 103 IFIISGNGEVIQPDDDAAAIGSGGPY 128 >5LOY-A nrPDB Length = 240 Score = 52.5 bits (124), Expect = 2e-07, Method: Composition-based stats. Identities = 32/189 (16%), Positives = 60/189 (31%), Gaps = 8/189 (4%) Query: 66 TTIVALTYKGGVLLAGDRRATQG-NLIASRDVEKVYVTD--EYSAAGIAGTAGIAIELVR 122 T V + G++ A D R G + I++ V+ AG ++ Sbjct: 1 TYCVGIRLDEGLVFASDSRTNAGVDNISTFRKMHVFEVPGERVIVLLTAGNLATTQAVIS 60 Query: 123 LFAVELEHYEKIEGVPLTFDGKANRLASMVRGNLGAAMQGLAV--VPLLVGYDLDADDES 180 L L+ E+ + A + +R L V + L Sbjct: 61 LLEERLKDPEERLLTAPSMFEAARLVGEALREVQARDAPALEADGVDFNASFILGGQIAG 120 Query: 181 RAGRIVSYDVVGGRYEER--AGYHAVGSGSLFAKSALKKIYSPDSDEETALRAAIESLYD 238 R+ G E + +G + + K L ++ +PD+ E A + A+ S Sbjct: 121 EPPRLFLIYPAGNFIEATPDTPFFQIGE-TKYGKPILDRVITPDTSLEDAAKCALVSFDS 179 Query: 239 AADDDSATG 247 + + G Sbjct: 180 TMRSNLSVG 188 >5NYW-A nrPDB Length = 251 Score = 47.1 bits (110), Expect = 9e-06, Method: Composition-based stats. Identities = 39/202 (19%), Positives = 68/202 (33%), Gaps = 13/202 (6%) Query: 66 TTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDE----YSAAGIAGTAGIAIELV 121 T VA+ G+ A D R G + K+++ + AG +V Sbjct: 1 TYCVAMRLSSGLAFASDSRTNAG-VDHISTFRKLHLFQQPGERTLVVQSAGNLATTQSIV 59 Query: 122 RLFAVELEHYEKIEGVPL-TFDGKANRLASMVRGNLGA---AMQGLAVVPLLVGYDLDAD 177 L E+ + + + A L VR + A Q L Sbjct: 60 SLLQRRCLDPEQTNLMNVASMYEAATLLGETVREVINRDSGAQQNSHGTDFNCNLLLGGQ 119 Query: 178 DESRAGRIVSYDVVGGRYEERA--GYHAVGSGSLFAKSALKKIYSPDSDEETALRAAIES 235 + R+ G E Y +G S + K + ++ S D+ + A++ A+ S Sbjct: 120 IKGEGLRLFHIYPQGNFIEATQDTPYFQIGE-SKYGKPIIDRVLSYDTPLDQAMQCALIS 178 Query: 236 LYDAADDDSATGGPDLTRGIYP 257 + D+ + + G L IYP Sbjct: 179 M-DSTLRSNLSVGLPLDVMIYP 199 >5LOX-A nrPDB Length = 242 Score = 44.8 bits (104), Expect = 4e-05, Method: Composition-based stats. Identities = 40/221 (18%), Positives = 71/221 (32%), Gaps = 27/221 (12%) Query: 66 TTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVT----DEYSAAGIAGTAGIAIELV 121 T VA+ G++ A D R G + K++ + AG + ++ Sbjct: 1 TYCVAMHLADGLVFASDSRTNAG-IDHIATFRKLFTFGTPGERLLVVQTAGNLATSQSVI 59 Query: 122 RLFAVELEH-YEKIEGVPLTFDGKANRLASMVRGNLG------AAMQGLAVVPLLVGYDL 174 L + + VP +D A +A R + A L+ ++ G Sbjct: 60 NLLQQRIRRDGASLLNVPSVYDATA-LVAETTREVMARDSGNLAGNTDLSCSFMVGGQIA 118 Query: 175 DADDESRAGRIVSYDVVGGRYEER--AGYHAVGSGSLFAKSALKKIYSPDSDEETALRAA 232 + S G + + +G S + K L + + D+ E ALR A Sbjct: 119 GGP-----PALYSIYPQGNFIQATPDTPFLQLGE-SKYGKPILDRNLTFDTPLEQALRCA 172 Query: 233 IESLYDAADDDSATGGP------DLTRGIYPTAVTITQAGA 267 + S + + G P I P +T+ A Sbjct: 173 LVSFDSTIRSNLSVGMPLDLLVYHRDSLILPEGYRVTEDDA 213 >5NYF-A nrPDB Length = 245 Score = 41.7 bits (96), Expect = 4e-04, Method: Composition-based stats. Identities = 36/197 (18%), Positives = 60/197 (30%), Gaps = 14/197 (7%) Query: 65 GTTIVALTYKGGVLLAGDRRATQG--NLIASRDVEKVYVTDEYS-AAGIAGTAGIAIELV 121 GT VA + G++ A D R G N+ + ++ E AG +V Sbjct: 2 GTYAVAFRLERGLVFAADTRTNAGVDNIAQYKKLQLWRQPGERVFVLLSAGNLAATQAVV 61 Query: 122 RLFAVELEHYEKIEGVPLTFDGKANRLASMV-------RGNLGAAMQGLAVVPLLVGYDL 174 L L E L R A +V R GAA++ + + Sbjct: 62 SLINEHLSQETDDEVTTLFTAPNMYRAARVVGDAVREARSIDGAALEASKLG-FNTNFIF 120 Query: 175 DADDESRAGRIVSYDVVGGRYEERA--GYHAVGSGSLFAKSALKKIYSPDSDEETALRAA 232 + R+ G E + +G + K L ++ D A + Sbjct: 121 GGQIKGERPRLFQIYPEGNFIEATDDTPFFQIGE-HKYGKPILDRVARSDMRLGEAAKLM 179 Query: 233 IESLYDAADDDSATGGP 249 + S + + G P Sbjct: 180 LLSFDSTLRSNLSVGMP 196 >1Q5Q-A nrPDB Length = 259 Score = 37.4 bits (85), Expect = 0.007, Method: Composition-based stats. Identities = 29/176 (16%), Positives = 54/176 (30%), Gaps = 10/176 (5%) Query: 64 HGTTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAGTAGIAIELVRL 123 G ++V LT++ GVL + +T + KV + G L R Sbjct: 26 RGRSVVVLTFRDGVLFVAENPSTA--------LHKVSELYDRLGFAAVGKYNEFENLRRA 77 Query: 124 FAVELEHYEKIEGVPLTFDGKANRLASMVRGNLGAAMQGLAVVPLLVGYDLDADDESRAG 183 V + + G + V + V ++ +A Sbjct: 78 GIVHADMRGYSYDRRDVTGRSLANAYAQTLGTIFTEQPKPYEVEICVA-EVGRVGSPKAP 136 Query: 184 RIVSYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDSDEETALRAAIESLYDA 239 ++ G +E+ G+ A + + Y D D E A+ A+ +L Sbjct: 137 QLYRITYDGSIVDEQHFVVMGGTTEPIATAMRES-YRADLDLEAAVGIAVNALRQG 191 >6JO3-A nrPDB Length = 253 Score = 30.5 bits (67), Expect = 0.82, Method: Composition-based stats. Identities = 32/177 (18%), Positives = 50/177 (28%), Gaps = 19/177 (10%) Query: 39 PENRIGHRSHSTRGGDGMESGDLAPHGTTIVALTYKGGVLLAGDRRATQG--NLIASRDV 96 P + M D G + D RA + I ++ Sbjct: 24 PGAKPPQECARIAEEAEMAGTDFIMVGGST-----------DIDSRAMDEAISAIKAKTD 72 Query: 97 EKVYVTDEYSAAGIAGTAGIAIELVRLFAVELEHYEKIEGVPLTFDGKANRLASMVRGNL 156 KV + S AI + L Y V A ++ + L Sbjct: 73 LKVIIFPGSSLMISP--KADAIFFMSLLNSGSLEYVVGHQVKAAIPLSAMKIEKIPMAYL 130 Query: 157 GAAMQGLAVVPLLVGYDLDADDESRAGRIVSYDVVGGRYEERAGYHAVGSGSLFAKS 213 G+ V + + + DDE A +SY + + R Y GSGS + Sbjct: 131 VFD-PGMTVGRVGKAHLIPRDDEKTA---LSYALAAQYFGFRLVYFEAGSGSPYHVG 183 >5GZU-A nrPDB Length = 885 Score = 27.8 bits (60), Expect = 6.5, Method: Composition-based stats. Identities = 27/137 (19%), Positives = 42/137 (30%), Gaps = 13/137 (9%) Query: 50 TRGGDGMESGDLAPHGTTIVAL--TYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSA 107 + G + G GT +A G + + T +I++ DV T Sbjct: 393 AKSGTPLSVGTSVYAGTVTMATYTQLPAGTFILPLTQGTLKPVISASDV-----TVSGIP 447 Query: 108 AGIAGTAGIAIELVRLFAVELEHYEKIEGV------PLTFDGKANRLASMVRGNLGAAMQ 161 AGI T A + AV + V + A A+M + Sbjct: 448 AGITYTVANAADHRNAVAVYVNGGTVASNVYDPIDVRVVVKASAVLEANMTDSAPASVTI 507 Query: 162 GLAVVPLLVGYDLDADD 178 P+L+GY D Sbjct: 508 MPKFGPILLGYVPGWVD 524 >5HH3-A nrPDB Length = 397 Score = 27.0 bits (58), Expect = 9.6, Method: Composition-based stats. Identities = 14/49 (28%), Positives = 23/49 (46%), Gaps = 1/49 (2%) Query: 247 GGPDLTRGIYPTAVTITQA-GAVHVSEETTSELARRIVAERTEQGGSAR 294 GGP + +V T + + + ++LAR + A RTE+ G R Sbjct: 137 GGPVDFVPRFGWSVATTATCDFLGIPRDDQADLARSLHASRTERSGKRR 185 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.309 0.125 0.310 Lambda K H 0.267 0.0379 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 9,988,927 Number of Sequences: 36641 Number of extensions: 382560 Number of successful extensions: 1122 Number of sequences better than 10.0: 90 Number of HSP's better than 10.0 without gapping: 128 Number of HSP's successfully gapped in prelim test: 36 Number of HSP's that attempted gapping in prelim test: 861 Number of HSP's gapped (non-prelim): 168 length of query: 294 length of database: 10,336,785 effective HSP length: 96 effective length of query: 198 effective length of database: 6,819,249 effective search space: 1350211302 effective search space used: 1350211302 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.7 bits) S2: 58 (27.1 bits)