BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q46856 (387 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 4QGS-A nrPDB 793 0.0 1VLJ-A nrPDB 220 1e-57 3OX4-A nrPDB 96 3e-20 3BFJ-A nrPDB 94 1e-19 3ZDR-A nrPDB 91 6e-19 2BI4-A nrPDB 89 2e-18 3IV7-A nrPDB 44 9e-05 5FB3-A nrPDB 34 0.084 1TA9-A nrPDB 34 0.11 3B52-X nrPDB 32 0.65 1B9C-A nrPDB 31 0.81 1JPU-A nrPDB 31 0.82 1KQ3-A nrPDB 31 0.89 3P28-A nrPDB 31 0.96 6C5C-A nrPDB 30 1.5 6OSU-A nrPDB 30 2.5 1XAI-A nrPDB 28 6.1 5GUW-B nrPDB 28 6.6 1MXS-A nrPDB 28 6.7 4BWR-A nrPDB 28 7.3 3OKF-A nrPDB 28 9.7 >4QGS-A nrPDB Length = 398 Score = 793 bits (2047), Expect = 0.0, Method: Compositional matrix adjust. Identities = 386/387 (99%), Positives = 386/387 (99%) Query: 1 MNNFNLHTPTRILFGKGAIAGLREQIPHDARVLITYGGGSVKKTGVLDQVLDALKGMDVL 60 MNNFNLHTPTRILFGKGAIAGLREQIPHDARVLITYGGGSVKKTGVLDQVLDALKGMDVL Sbjct: 12 MNNFNLHTPTRILFGKGAIAGLREQIPHDARVLITYGGGSVKKTGVLDQVLDALKGMDVL 71 Query: 61 EFGGIEPNPAYETLMNAVKLVREQKVTFLLAVGGGSVLDGTKFIAAAANYPENIDPWHIL 120 EFGGIEPNPAYETLMNAVKLVREQKVTFLLAVGGGSVLDGTKFIAAAANYPENIDPWHIL Sbjct: 72 EFGGIEPNPAYETLMNAVKLVREQKVTFLLAVGGGSVLDGTKFIAAAANYPENIDPWHIL 131 Query: 121 QTGGKEIKSAIPMGCVLTLPATGSESNAGAVISRKTTGDKQAFHSAHVQPVFAVLDPVYT 180 QTGGKEIKSAIPMGCVLTLPATGSESNAGAVISRKTTGDKQAFHSAHVQPVFAVLDPVYT Sbjct: 132 QTGGKEIKSAIPMGCVLTLPATGSESNAGAVISRKTTGDKQAFHSAHVQPVFAVLDPVYT 191 Query: 181 YTLPPRQVANGVVDAFVHTVEQYVTKPVDAKIQDRFAEGILLTLIEDGPKALKEPENYDV 240 YTLPPRQVANGVVDAFVHTVEQYVTKPVDAKIQDRFAEGILLTLIEDGPKALKEPENYDV Sbjct: 192 YTLPPRQVANGVVDAFVHTVEQYVTKPVDAKIQDRFAEGILLTLIEDGPKALKEPENYDV 251 Query: 241 RANVMWAATQALNGLIGAGVPQDWATHMLGHELTAMHGLDHAQTLAIVLPALWNEKRDTK 300 RANVMWAATQA NGLIGAGVPQDWATHMLGHELTAMHGLDHAQTLAIVLPALWNEKRDTK Sbjct: 252 RANVMWAATQAENGLIGAGVPQDWATHMLGHELTAMHGLDHAQTLAIVLPALWNEKRDTK 311 Query: 301 RAKLLQYAERVWNITEGSDDERIDAAIAATRNFFEQLGVPTHLSDYGLDGSSIPALLKKL 360 RAKLLQYAERVWNITEGSDDERIDAAIAATRNFFEQLGVPTHLSDYGLDGSSIPALLKKL Sbjct: 312 RAKLLQYAERVWNITEGSDDERIDAAIAATRNFFEQLGVPTHLSDYGLDGSSIPALLKKL 371 Query: 361 EEHGMTQLGENHDITLDVSRRIYEAAR 387 EEHGMTQLGENHDITLDVSRRIYEAAR Sbjct: 372 EEHGMTQLGENHDITLDVSRRIYEAAR 398 >1VLJ-A nrPDB Length = 407 Score = 220 bits (560), Expect = 1e-57, Method: Compositional matrix adjust. Identities = 133/362 (36%), Positives = 211/362 (58%), Gaps = 10/362 (2%) Query: 1 MNNFNLHTPTRILFGKGAIAGLREQIPHDA--RVLITYGGGSVKKTGVLDQVLDALK--G 56 M NF H PT+I+FG+G I + E+I + +VL YGGGS+KK GV DQV+D+LK G Sbjct: 13 MENFVFHNPTKIVFGRGTIPKIGEEIKNAGIRKVLFLYGGGSIKKNGVYDQVVDSLKKHG 72 Query: 57 MDVLEFGGIEPNPAYETLMNAVKLVREQKVTFLLAVGGGSVLDGTKFIAAAANYPENIDP 116 ++ +E G++PNP + AV++ +++KV +L VGGGSV+D K +AA A Y +I Sbjct: 73 IEWVEVSGVKPNPVLSKVHEAVEVAKKEKVEAVLGVGGGSVVDSAKAVAAGALYEGDI-- 130 Query: 117 WHILQTGGKEIKSAIPMGCVLTLPATGSESNAGAVISRKTTGDKQAFHSAHVQPVFAVLD 176 W G +I+ A+P+ VLT+ ATG+E N AVI+ + T +K S + P +++D Sbjct: 131 WDAF-IGKYQIEKALPIFDVLTISATGTEMNGNAVITNEKTKEKYGVSSKALYPKVSIID 189 Query: 177 PVYTYTLPPRQVANGVVDAFVHTVEQYVTKPVDAKIQDRFAEGILLTLIEDGPKALKEPE 236 P +TLP Q G VDA H +E Y +I + AEG + T+++ + +++P+ Sbjct: 190 PSVQFTLPKEQTVYGAVDAISHILEYYFDGS-SPEISNEIAEGTIRTIMKMTERLIEKPD 248 Query: 237 NYDVRANVMWAATQALNGLIGAGVP-QDWATHMLGHELTAMHGLDHAQTLAIVLPALWNE 295 +Y+ RAN+ W+AT ALNG + G +WA H + H L+A++ + H LAIV PA Sbjct: 249 DYEARANLAWSATIALNGTMAVGRRGGEWACHRIEHSLSALYDIAHGAGLAIVFPAWMKY 308 Query: 296 KRDTKRAKLLQYAERVWNITEGSDDERIDAAIAATRNFFEQLGVPTHLSDYGLDGSSIPA 355 A+ ++A++++ EG +E I I A +N+ +++G P L D G+ I Sbjct: 309 VYRKNPAQFERFAKKIFGF-EGEGEELILKGIEAFKNWLKKVGAPVSLKDAGIPEEDIDK 367 Query: 356 LL 357 ++ Sbjct: 368 IV 369 >3OX4-A nrPDB Length = 383 Score = 95.5 bits (236), Expect = 3e-20, Method: Compositional matrix adjust. Identities = 82/320 (25%), Positives = 142/320 (44%), Gaps = 12/320 (3%) Query: 41 VKKTGVLDQVLDALK--GMDVLEFGGIEPNPAYETLMNAVKLVREQKVTFLLAVGGGSVL 98 + K+GV+ QV D LK G++ + G+ PNP ++ +K++++ F++++GGGS Sbjct: 42 MNKSGVVKQVADLLKAQGINSAVYDGVMPNPTVTAVLEGLKILKDNNSDFVISLGGGSPH 101 Query: 99 DGTKFIAAAANYPENIDPWHILQTGGKEIKSAIPMGCVLTLPATGSESNAGAVISRKTTG 158 D K IA A + + + K K A+P+ + T T SE +I+ + Sbjct: 102 DCAKAIALVATNGGEVKDYEGID---KSKKPALPLMSINTTAGTASEMTRFCIITDEVRH 158 Query: 159 DKQAFHSAHVQPVFAVLDPVYTYTLPPRQVANGVVDAFVHTVEQYVTKPVDAKIQDRFAE 218 K A HV P+ +V DP+ +P A +DA H E Y + I D A Sbjct: 159 VKMAIVDRHVTPMVSVNDPLLMVGMPKGLTAATGMDALTHAFEAY-SSTAATPITDACAL 217 Query: 219 GILLTLIEDGPKALKEPENYDVRANVMWAATQALNGLIGAGVPQDWATHMLGHELTAMHG 278 + ++ A ++ R + +A Q L G+ + H + H+L + Sbjct: 218 KAASMIAKNLKTACDNGKDMPAREAMAYA--QFLAGMAFNNASLGY-VHAMAHQLGGYYN 274 Query: 279 LDHAQTLAIVLPAL--WNEKRDTKRAKLLQYAERVWNITEGSDDERIDAAIAATRNFFEQ 336 L H A++LP + +N R K + A + +I D E +A I A R+ Sbjct: 275 LPHGVCNAVLLPHVLAYNASVVAGRLKDVGVAMGL-DIANLGDKEGAEATIQAVRDLAAS 333 Query: 337 LGVPTHLSDYGLDGSSIPAL 356 +G+P +L++ G +P L Sbjct: 334 IGIPANLTELGAKKEDVPLL 353 >3BFJ-A nrPDB Length = 387 Score = 94.0 bits (232), Expect = 1e-19, Method: Compositional matrix adjust. Identities = 92/359 (25%), Positives = 155/359 (43%), Gaps = 13/359 (3%) Query: 4 FNLHTPTRILFGKGAIA--GLREQIPHDAR-VLITYGGGSVKKTGVLDQVLDALK--GMD 58 F+ P FG AI+ G R Q+ + +L+T G K G +D+ L L+ G++ Sbjct: 6 FDYLVPNVNFFGPNAISVVGERCQLLGGKKALLVTDKGLRAIKDGAVDKTLHYLREAGIE 65 Query: 59 VLEFGGIEPNPAYETLMNAVKLVREQKVTFLLAVGGGSVLDGTKFIAAAANYPENIDPWH 118 V F G+EPNP + + + + R ++ ++ VGGGS D K I AA + ++ + Sbjct: 66 VAIFDGVEPNPKDTNVRDGLAVFRREQCDIIVTVGGGSPHDCGKGIGIAATHEGDLYQYA 125 Query: 119 ILQTGGKEIKSAIPMGCVLTLPATGSESNAGAVISRKTTGDKQAFHSAHVQPVFAVLDPV 178 ++T + P+ V T T SE V++ T K S P ++ DP+ Sbjct: 126 GIETLTNPLP---PIVAVNTTAGTASEVTRHCVLTNTETKVKFVIVSWRNLPSVSINDPL 182 Query: 179 YTYTLPPRQVANGVVDAFVHTVEQYVTKPVDAKIQDRFAEGILLTLIEDGPKALKEPENY 238 P A +DA H VE Y++K + + D A + + + +A+ N Sbjct: 183 LMIGKPAALTAATGMDALTHAVEAYISKDAN-PVTDAAAMQAIRLIARNLRQAVALGSNL 241 Query: 239 DVRANVMWAATQALNGLIGAGVPQDWATHMLGHELTAMHGLDHAQTLAIVLPALWNEKRD 298 R + +A+ A A + H + H+L ++ + H A++LP + Sbjct: 242 QAREYMAYASLLAGMAFNNANL---GYVHAMAHQLGGLYDMPHGVANAVLLPHVARYNLI 298 Query: 299 TKRAKLLQYAERVW-NITEGSDDERIDAAIAATRNFFEQLGVPTHLSDYGLDGSSIPAL 356 K AE + NIT S + + AIAA +G+P HL D G+ + P + Sbjct: 299 ANPEKFADIAELMGENITGLSTLDAAEKAIAAITRLSMDIGIPQHLRDLGVKETDFPYM 357 >3ZDR-A nrPDB Length = 433 Score = 91.3 bits (225), Expect = 6e-19, Method: Compositional matrix adjust. Identities = 100/396 (25%), Positives = 170/396 (42%), Gaps = 49/396 (12%) Query: 1 MNNFNLHTPTRILFGKGAIAGLREQIPHDARVLITYGGGSVKKTGVLDQVLDALKGM-DV 59 MN P +I F K A+ L ++P +R I G VK G +D+VL L+ D Sbjct: 22 MNMQWFKVPPKIYFEKNAVQYL-AKMPDISRAFIVTDPGMVK-LGYVDKVLYYLRRRPDY 79 Query: 60 LE---FGGIEPNPAYETLMNAVKLVREQKVTFLLAVGGGSVLDGTKFIAAAANYP----- 111 + F +EP+P+ ET+M V ++R + ++A+GGGS +D K + +P Sbjct: 80 VHSEIFSEVEPDPSIETVMKGVDMMRSFEPDVIIALGGGSPMDAAKAMWLFYEHPTADFN 139 Query: 112 ----ENID----PWHILQTGGKEIKSAIPMGCVLTLPATGSESNAGAVISRKTTGDKQAF 163 + +D + + G K AIP T TGSE + AVI+ K T K Sbjct: 140 ALKQKFLDIRKRVYKYPKLGQKAKFVAIP-----TTSGTGSEVTSFAVITDKKTNIKYPL 194 Query: 164 HSAHVQPVFAVLDPVYTYTLPPRQVANGVVDAFVHTVEQYVTKPVDAKIQDRFAEGILLT 223 + P A++DP + T+P A+ +D H +E YV+ + D A + Sbjct: 195 ADYELTPDVAIVDPQFVMTVPKHVTADTGMDVLTHAIEAYVSNMAN-DYTDGLAMKAIQL 253 Query: 224 LIEDGPKALKEPENYDVRANVMWAATQA----LNGLIGAGVPQDWATHMLGHELTAMHGL 279 + E P+A + + R + A+T A N +G H L H+L A + Sbjct: 254 VFEYLPRAYQNGADELAREKMHNASTIAGMAFANAFLGIN-------HSLAHKLGAEFHI 306 Query: 280 DHAQTLAIVLPAL--WNEKRDTKRAKL---------LQYAE--RVWNITEGSDDERIDAA 326 H + I++P + +N + K +YAE R+ + + +E +++ Sbjct: 307 PHGRANTILMPHVIRYNAAKPKKFTAFPKYEYFKADQRYAEIARMLGLPARTTEEGVESL 366 Query: 327 IAATRNFFEQLGVPTHLSDYGLDGSSIPALLKKLEE 362 + A +QL +P + G+ + ++KL E Sbjct: 367 VQAIIKLAKQLDMPLSIEACGVSKQEFESKVEKLAE 402 >2BI4-A nrPDB Length = 392 Score = 89.4 bits (220), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 99/382 (25%), Positives = 159/382 (41%), Gaps = 22/382 (5%) Query: 14 FGKGAIAGLREQIPHDA--RVLITYGGGSVKKTGVLDQVLDALK--GMDVLEFGGIEPNP 69 FG+GA+ L +++ + LI ++ + GV+ +V D + G+ + G+ PNP Sbjct: 23 FGRGAVGALTDEVKRRGYQKALIVTDK-TLVQCGVVAKVTDKMDAAGLAWAIYDGVVPNP 81 Query: 70 AYETLMNAVKLVREQKVTFLLAVGGGSVLDGTKFIAAAANYPENIDPWHILQTGGKEIKS 129 + + + + +L+A+GGGS D K I +N PE D L+ K Sbjct: 82 TITVVKEGLGVFQNSGADYLIAIGGGSPQDTCKAIGIISNNPEFAD-VRSLEGLSPTNKP 140 Query: 130 AIPMGCVLTLPATGSESNAGAVISRKTTGDKQAFHSAHVQPVFAVLDPVYTYTLPPRQVA 189 ++P+ + T T +E VI+ + K H P A +D +PP A Sbjct: 141 SVPILAIPTTAGTAAEVTINYVITDEEKRRKFVCVDPHDIPQVAFIDADMMDGMPPALKA 200 Query: 190 NGVVDAFVHTVEQYVTKPVDAKIQDRFAEGILLTLIEDGPKALKEPENYDVRANVMWAAT 249 VDA H +E Y+T+ A + + + IE AL+ D A A Sbjct: 201 ATGVDALTHAIEGYITRGAWA-----LTDALHIKAIEIIAGALRGSVAGDKDAGEEMALG 255 Query: 250 QALNGL----IGAGVPQDWATHMLGHELTAMHGLDHAQTLAIVLPALWNEKRDTKRAKLL 305 Q + G+ +G G+ H + H L A + H AI+LP + D K Sbjct: 256 QYVAGMGFSNVGLGL-----VHGMAHPLGAFYNTPHGVANAILLPHVMRYNADFTGEKYR 310 Query: 306 QYAERVWNITEG-SDDERIDAAIAATRNFFEQLGVPTHLSDYGLDGSSIPALLKKLEEHG 364 A + EG S +E +AA+ A +G+P HL D G+ IPAL + + Sbjct: 311 DIARVMGVKVEGMSLEEARNAAVEAVFALNRDVGIPPHLRDVGVRKEDIPALAQAALDDV 370 Query: 365 MTQLGENHDITLDVSRRIYEAA 386 T G + TL+ +Y A Sbjct: 371 CTG-GNPREATLEDIVELYHTA 391 >3IV7-A nrPDB Length = 364 Score = 44.3 bits (103), Expect = 9e-05, Method: Compositional matrix adjust. Identities = 86/369 (23%), Positives = 140/369 (37%), Gaps = 68/369 (18%) Query: 1 MNN---FNLHT-PTRILFGKG-AIAGLREQIPH--DARVLITYGGGSVKKT-GVLDQVLD 52 MNN FN T P +++FG G + A L++++ A+V++ G + V ++ Sbjct: 2 MNNSLAFNHDTLPQKVMFGYGKSSAFLKQEVERRGSAKVMVIAGEREMSIAHKVASEIEV 61 Query: 53 ALKGMDVLEFGGIEPNPAYETLMNAVKLVREQKVTFLLAVGGGSVLDGTKFIAAAANYPE 112 A+ +V+ IE A + + ++ L+ VGGGS + K IA Sbjct: 62 AIWHDEVVMHVPIE------VAERARAVATDNEIDLLVCVGGGSTIGLAKAIA------- 108 Query: 113 NIDPWHILQTGGKEIKSAIPMGCVLTLPATGSESNAGAV-----ISRKTTGDKQAFHSAH 167 + +A+P ++ +P T + S A V +RKTTG Sbjct: 109 --------------MTTALP---IVAIPTTYAGSEATNVWGLTEAARKTTGVDL-----K 146 Query: 168 VQPVFAVLDPVYTYTLPPRQVANGVVDAFVHTVEQY---VTKPVDAKIQDRFAEGILLTL 224 V P + D T +LP ++ H ++ P++A + AEGI L Sbjct: 147 VLPETVIYDSELTMSLPVEMSVASGLNGLAHCIDSLWGPNADPINAVLA---AEGIR-AL 202 Query: 225 IEDGPKALKEPENYDVRANVMWAATQALNGLIGAGVPQDWATHMLGHELTAMHGLDHAQT 284 + PK + P + + R ++ A A AG H + H L L HAQT Sbjct: 203 NQGLPKIVANPHSIEGRDEALYGAYLAAVSFASAG---SGLHHKICHTLGGTFNLPHAQT 259 Query: 285 LAIVLPALWNEKRDTKRAKLLQYAERVWNITEGSDDERIDAAIAATRNFFEQLGVPTHLS 344 A VLP + + + D A+ + + P LS Sbjct: 260 HATVLPYVL----------AFNAGDAPEAERRAAAAFGTDTALEGLQRLRLSVNAPKRLS 309 Query: 345 DYGLDGSSI 353 DYG + S I Sbjct: 310 DYGFEASGI 318 >5FB3-A nrPDB Length = 338 Score = 34.3 bits (77), Expect = 0.084, Method: Compositional matrix adjust. Identities = 27/100 (27%), Positives = 43/100 (43%), Gaps = 19/100 (19%) Query: 5 NLHTPTRILFGKGAIAGLREQIPHDARVLITYGGGSVKKTGVLDQVLDALK-GMDVLEFG 63 P I+FG GA+ E IP RVLI G S +K ++V + LK +++ + Sbjct: 6 RFEVPRTIIFGPGALEKTPEVIPPSGRVLIITGKSSTRKYA--ERVAELLKQNCEIISYD 63 Query: 64 GIE-PNPAYETLMNAVKLVREQKVTFLLAVGGGSVLDGTK 102 +E P ++ ++ +GGG LD K Sbjct: 64 QVELEKPGFD---------------LVIGIGGGRPLDMAK 88 >1TA9-A nrPDB Length = 450 Score = 33.9 bits (76), Expect = 0.11, Method: Compositional matrix adjust. Identities = 61/256 (23%), Positives = 95/256 (37%), Gaps = 56/256 (21%) Query: 48 DQVLDALK--GMDV--LEFGGIEPNPAYETLMNAVKLVREQ---KVTFLLAVGGGSVLDG 100 ++++D+L GM V L FGG E + + +R+Q ++ VGGG +D Sbjct: 108 NKIVDSLSQNGMTVTKLVFGG-------EASLVELDKLRKQCPDDTQVIIGVGGGKTMDS 160 Query: 101 TKFIAAAANYPENIDPWHILQTGGKEIKSAIPMGCVLTLPATGSESNAGAVISRKTT--G 158 K+IA + N P I P T S A + +S T G Sbjct: 161 AKYIAHSMNLPSII------------------------CPTTASSDAATSSLSVIYTPDG 196 Query: 159 DKQAFHSAHVQPVFAVLDPVYTYTLPPRQVANGVVDAFVHTVEQYVTKPVDAKIQDRFAE 218 Q + + P +D P R + +G+ DA VE T+ V FA Sbjct: 197 QFQKYSFYPLNPNLIFIDTDVIVRAPVRFLISGIGDALSTWVE---TESVIRSNSTSFAG 253 Query: 219 GILLTLIEDGPKALKEP-ENYDVRA---NVMWAATQALNGLIGAGVPQD---------WA 265 G+ +A K+ E Y + A N T+A ++ A A Sbjct: 254 GVASIAGRYIARACKDTLEKYALSAILSNTRGVCTEAFENVVEANTLMSGLGFENGGLAA 313 Query: 266 THMLGHELTAMHGLDH 281 H + + +TA+HG H Sbjct: 314 AHAIHNGMTAIHGPVH 329 Score = 28.5 bits (62), Expect = 4.8, Method: Compositional matrix adjust. Identities = 16/39 (41%), Positives = 23/39 (58%), Gaps = 4/39 (10%) Query: 5 NLHTPTRILFGKGA----IAGLREQIPHDARVLITYGGG 39 N T T+++FG A + LR+Q P D +V+I GGG Sbjct: 117 NGMTVTKLVFGGEASLVELDKLRKQCPDDTQVIIGVGGG 155 >3B52-X nrPDB Length = 656 Score = 31.6 bits (70), Expect = 0.65, Method: Compositional matrix adjust. Identities = 39/126 (30%), Positives = 55/126 (43%), Gaps = 18/126 (14%) Query: 255 LIGAGVPQDWATHMLGHELTAMHGLDHAQTLAIVLPALWNEKRDTKRAKLLQYAERVWNI 314 ++ G+ + A GH A H L H A+ A +D R KL A+R+ Sbjct: 97 IVARGLDRSIAAGAAGHSGHAKH-LAHTLKKAVQGKAASYMIKD--RTKLHSIAKRLGIP 153 Query: 315 TEGSDDERI--DAAIAATRNFFEQ----LGVPTHLSDYGLDGSSIPALLKKLEEHGMTQL 368 TEG DE I + A AA +F E+ L V T L P+ +K L HG+ Sbjct: 154 TEGQKDEDIALEVAKAALADFHEKDTPVLWVTTVLP---------PSRVKVLSAHGLIPA 204 Query: 369 GENHDI 374 G +H+I Sbjct: 205 GIDHEI 210 >1B9C-A nrPDB Length = 238 Score = 31.2 bits (69), Expect = 0.81, Method: Compositional matrix adjust. Identities = 19/82 (23%), Positives = 36/82 (43%) Query: 192 VVDAFVHTVEQYVTKPVDAKIQDRFAEGILLTLIEDGPKALKEPENYDVRANVMWAATQA 251 +V F + V+ + P K D F + +++ + K+ NY RA V + Sbjct: 60 LVTTFTYGVQCFSRYPDHMKQHDFFKSAMPEGYVQERTISFKDDGNYKTRAEVKFEGDTL 119 Query: 252 LNGLIGAGVPQDWATHMLGHEL 273 +N + G+ ++LGH+L Sbjct: 120 VNRIELKGIDFKEDGNILGHKL 141 >1JPU-A nrPDB Length = 370 Score = 31.2 bits (69), Expect = 0.82, Method: Compositional matrix adjust. Identities = 32/140 (22%), Positives = 57/140 (40%), Gaps = 25/140 (17%) Query: 62 FGGIEPNPAYETLMNAVKLVREQKVTFLLAVGGGSVLDGTKFIAAAANYPENIDPWHILQ 121 F G E + N + R+ + ++ VGGG LD K +A + +D + ++ Sbjct: 66 FSGEASRNEVERIAN---IARKAEAAIVIGVGGGKTLDTAKAVA------DELDAYIVI- 115 Query: 122 TGGKEIKSAIPMGCVLTLPATGSESNAGAVISRKTTGDKQAFHSAHVQPVFAVLDPVYTY 181 V T +T + ++A +VI G +++ P ++D Sbjct: 116 --------------VPTAASTDAPTSALSVI-YSDDGVFESYRFYKKNPDLVLVDTKIIA 160 Query: 182 TLPPRQVANGVVDAFVHTVE 201 PPR +A+G+ DA VE Sbjct: 161 NAPPRLLASGIADALATWVE 180 >1KQ3-A nrPDB Length = 376 Score = 31.2 bits (69), Expect = 0.89, Method: Compositional matrix adjust. Identities = 15/36 (41%), Positives = 23/36 (63%) Query: 327 IAATRNFFEQLGVPTHLSDYGLDGSSIPALLKKLEE 362 I +F E++G+PT L++ GLDG S L+K E+ Sbjct: 303 IEEVYSFCEEVGLPTTLAEIGLDGVSDEDLMKVAEK 338 >3P28-A nrPDB Length = 241 Score = 30.8 bits (68), Expect = 0.96, Method: Compositional matrix adjust. Identities = 19/82 (23%), Positives = 36/82 (43%) Query: 192 VVDAFVHTVEQYVTKPVDAKIQDRFAEGILLTLIEDGPKALKEPENYDVRANVMWAATQA 251 +V F + V+ + P K D F + +++ + K+ NY RA V + Sbjct: 12 LVTTFSYGVQCFSRYPDHMKRHDFFKSAMPEGYVQERTISFKDDGNYKTRAEVKFEGDTL 71 Query: 252 LNGLIGAGVPQDWATHMLGHEL 273 +N + G+ ++LGH+L Sbjct: 72 VNRIELKGIDFKEDGNILGHKL 93 >6C5C-A nrPDB Length = 390 Score = 30.4 bits (67), Expect = 1.5, Method: Compositional matrix adjust. Identities = 28/108 (25%), Positives = 45/108 (41%), Gaps = 20/108 (18%) Query: 87 TFLLAVGGGSVLDGTKFIAAAANYPENIDPWHILQTGGKEIKSAIPMGCVLTLPATGSES 146 T +LAVGGG + D F+AA + + + T + S++ G ++ Sbjct: 107 TVILAVGGGVIGDMIGFVAA--TFMRGVRVVQVPTTLLAMVDSSV-----------GGKT 153 Query: 147 NAGAVISRKTTGDKQAFHSAHVQPVFAVLDPVYTYTLPPRQVANGVVD 194 + + G AFH QP + D + TLP RQ NG+ + Sbjct: 154 AIDTPLGKNFIG---AFH----QPEYVFCDVSFLETLPARQFINGMAE 194 >6OSU-A nrPDB Length = 427 Score = 29.6 bits (65), Expect = 2.5, Method: Compositional matrix adjust. Identities = 15/43 (34%), Positives = 25/43 (58%) Query: 266 THMLGHELTAMHGLDHAQTLAIVLPALWNEKRDTKRAKLLQYA 308 T G+ L + D + +++VL + KRD++ AKLL+YA Sbjct: 282 TDAAGYCLVSSAKQDGERFISVVLGTTSSAKRDSESAKLLRYA 324 >1XAI-A nrPDB Length = 354 Score = 28.1 bits (61), Expect = 6.1, Method: Compositional matrix adjust. Identities = 48/252 (19%), Positives = 90/252 (35%), Gaps = 42/252 (16%) Query: 66 EPNPAYETLMNAVKLVREQKVT---FLLAVGGGSVLDGTKFIAAAANYPENIDPWHILQT 122 E +E ++ + VT ++AVGGG+ D F+AA + H +Q Sbjct: 68 EKTKTFEQYQETLEYILSHHVTRNTAIIAVGGGATGDFAGFVAATL-----LRGVHFIQ- 121 Query: 123 GGKEIKSAIPMGCVLTLPATGSESNAGAVISRKTTGDKQAFHSAHVQPVFAVLDPVYTYT 182 +P + + G + + + G A +P + D + T Sbjct: 122 --------VPTTILAHDSSVGGKVGINSKQGKNLIG-------AFYRPTAVIYDLDFLKT 166 Query: 183 LPPRQVANGVVDAFVHTVEQYVTKPVDAKIQDRFAEGILLTLIEDGPKALKEPENYDVRA 242 LP +Q+ +G + + H + + D I+ F + +L + K + + + Sbjct: 167 LPFKQILSGYAEVYKHALLNGESATQD--IEQHFKDREILQSLNGMDKYIAKGIETKLDI 224 Query: 243 NVMWAATQALNGLIGAGVPQDWATHMLGHELTAMHGLDHAQTLA-------IVLPALWNE 295 V Q + + G H GH + H + H + IV AL++ Sbjct: 225 VVADEKEQGVRKFLNLG-------HTFGHAVEYYHKIPHGHAVMVGIIYQFIVANALFDS 277 Query: 296 KRDTKRAKLLQY 307 K D + +QY Sbjct: 278 KHDI--SHYIQY 287 >5GUW-B nrPDB Length = 465 Score = 28.1 bits (61), Expect = 6.6, Method: Compositional matrix adjust. Identities = 18/54 (33%), Positives = 26/54 (48%), Gaps = 10/54 (18%) Query: 233 KEPENYDVRANVMWAATQALNGLIGAGV--------PQDWATHMLGHELTAMHG 278 + +Y RA +WA + +GAGV P ++ TH G +LTA HG Sbjct: 297 RRRRDYPNRAVALWAMGTTVMAFLGAGVWGFMHTLAPVNYYTH--GTQLTAAHG 348 >1MXS-A nrPDB Length = 225 Score = 28.1 bits (61), Expect = 6.7, Method: Compositional matrix adjust. Identities = 22/60 (36%), Positives = 31/60 (51%), Gaps = 5/60 (8%) Query: 52 DALKGMDVLEFGGI---EPNPAYETLMNAVKLVREQKVTFLLAVGGGSVLDGTKFIAAAA 108 D L D L GGI E + + A++++REQ+ L VG G+VLD + F A A Sbjct: 39 DILPLADALAAGGIRTLEVTLRSQHGLKAIQVLREQRPE--LCVGAGTVLDRSMFAAVEA 96 >4BWR-A nrPDB Length = 467 Score = 28.1 bits (61), Expect = 7.3, Method: Compositional matrix adjust. Identities = 13/32 (40%), Positives = 20/32 (62%) Query: 252 LNGLIGAGVPQDWATHMLGHELTAMHGLDHAQ 283 L + G GVPQD+A ++ ++ A+ GL AQ Sbjct: 60 LRYMNGEGVPQDYAQAVIWYKKAALKGLPQAQ 91 >3OKF-A nrPDB Length = 390 Score = 27.7 bits (60), Expect = 9.7, Method: Compositional matrix adjust. Identities = 34/139 (24%), Positives = 56/139 (40%), Gaps = 23/139 (16%) Query: 59 VLEFGGIEPNPAYETLMNAVKLVREQKVT---FLLAVGGGSVLDGTKFIAAAANYPENID 115 +LE E ET + + E + ++A+GGG + D F AAA Y +D Sbjct: 94 LLELPDGEQYKTLETFNTVMSFLLEHNYSRDVVVIALGGGVIGDLVGF--AAACYQRGVD 151 Query: 116 PWHILQTGGKEIKSAIPMGCVLTLPATGSESNAGAVISRKTTGDKQAFHSAHVQPVFAVL 175 I T ++ S++ G ++ + + G AF+ QP V+ Sbjct: 152 FIQIPTTLLSQVDSSV-----------GGKTAVNHPLGKNMIG---AFY----QPKAVVI 193 Query: 176 DPVYTYTLPPRQVANGVVD 194 D TLP R+ A G+ + Sbjct: 194 DTDCLTTLPAREFAAGMAE 212 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 4QGS-A nrPDB 512 e-146 3BFJ-A nrPDB 389 e-108 2BI4-A nrPDB 381 e-106 1VLJ-A nrPDB 371 e-103 3ZDR-A nrPDB 359 1e-99 3OX4-A nrPDB 346 9e-96 3IV7-A nrPDB 256 1e-68 Sequences not found previously or not previously below threshold: 5K8C-A nrPDB 110 1e-24 1JPU-A nrPDB 74 1e-13 1KQ3-A nrPDB 73 2e-13 5ZXL-A nrPDB 63 2e-10 5FB3-A nrPDB 63 3e-10 4MCA-A nrPDB 61 1e-09 3UHJ-A nrPDB 60 2e-09 5XN8-A nrPDB 58 6e-09 1TA9-A nrPDB 53 3e-07 1XAI-A nrPDB 52 5e-07 4RGQ-A nrPDB 44 1e-04 4RFL-A nrPDB 43 2e-04 3CE9-A nrPDB 41 8e-04 5HUQ-A nrPDB 34 0.13 3NDA-A nrPDB 31 1.2 5EZ7-A nrPDB 30 1.4 1NLT-A nrPDB 30 1.5 3LCV-B nrPDB 30 1.8 5GUW-B nrPDB 30 2.1 4P63-A nrPDB 29 3.1 3THU-A nrPDB 29 4.0 >4QGS-A nrPDB Length = 398 Score = 512 bits (1319), Expect = e-146, Method: Composition-based stats. Identities = 386/387 (99%), Positives = 386/387 (99%) Query: 1 MNNFNLHTPTRILFGKGAIAGLREQIPHDARVLITYGGGSVKKTGVLDQVLDALKGMDVL 60 MNNFNLHTPTRILFGKGAIAGLREQIPHDARVLITYGGGSVKKTGVLDQVLDALKGMDVL Sbjct: 12 MNNFNLHTPTRILFGKGAIAGLREQIPHDARVLITYGGGSVKKTGVLDQVLDALKGMDVL 71 Query: 61 EFGGIEPNPAYETLMNAVKLVREQKVTFLLAVGGGSVLDGTKFIAAAANYPENIDPWHIL 120 EFGGIEPNPAYETLMNAVKLVREQKVTFLLAVGGGSVLDGTKFIAAAANYPENIDPWHIL Sbjct: 72 EFGGIEPNPAYETLMNAVKLVREQKVTFLLAVGGGSVLDGTKFIAAAANYPENIDPWHIL 131 Query: 121 QTGGKEIKSAIPMGCVLTLPATGSESNAGAVISRKTTGDKQAFHSAHVQPVFAVLDPVYT 180 QTGGKEIKSAIPMGCVLTLPATGSESNAGAVISRKTTGDKQAFHSAHVQPVFAVLDPVYT Sbjct: 132 QTGGKEIKSAIPMGCVLTLPATGSESNAGAVISRKTTGDKQAFHSAHVQPVFAVLDPVYT 191 Query: 181 YTLPPRQVANGVVDAFVHTVEQYVTKPVDAKIQDRFAEGILLTLIEDGPKALKEPENYDV 240 YTLPPRQVANGVVDAFVHTVEQYVTKPVDAKIQDRFAEGILLTLIEDGPKALKEPENYDV Sbjct: 192 YTLPPRQVANGVVDAFVHTVEQYVTKPVDAKIQDRFAEGILLTLIEDGPKALKEPENYDV 251 Query: 241 RANVMWAATQALNGLIGAGVPQDWATHMLGHELTAMHGLDHAQTLAIVLPALWNEKRDTK 300 RANVMWAATQA NGLIGAGVPQDWATHMLGHELTAMHGLDHAQTLAIVLPALWNEKRDTK Sbjct: 252 RANVMWAATQAENGLIGAGVPQDWATHMLGHELTAMHGLDHAQTLAIVLPALWNEKRDTK 311 Query: 301 RAKLLQYAERVWNITEGSDDERIDAAIAATRNFFEQLGVPTHLSDYGLDGSSIPALLKKL 360 RAKLLQYAERVWNITEGSDDERIDAAIAATRNFFEQLGVPTHLSDYGLDGSSIPALLKKL Sbjct: 312 RAKLLQYAERVWNITEGSDDERIDAAIAATRNFFEQLGVPTHLSDYGLDGSSIPALLKKL 371 Query: 361 EEHGMTQLGENHDITLDVSRRIYEAAR 387 EEHGMTQLGENHDITLDVSRRIYEAAR Sbjct: 372 EEHGMTQLGENHDITLDVSRRIYEAAR 398 >3BFJ-A nrPDB Length = 387 Score = 389 bits (999), Expect = e-108, Method: Composition-based stats. Identities = 94/390 (24%), Positives = 159/390 (40%), Gaps = 14/390 (3%) Query: 3 NFNLHTPTRILFGKGAIA--GLREQIPHDARVLITYGGG-SVKKTGVLDQVLDALK--GM 57 F+ P FG AI+ G R Q+ + L+ G K G +D+ L L+ G+ Sbjct: 5 MFDYLVPNVNFFGPNAISVVGERCQLLGGKKALLVTDKGLRAIKDGAVDKTLHYLREAGI 64 Query: 58 DVLEFGGIEPNPAYETLMNAVKLVREQKVTFLLAVGGGSVLDGTKFIAAAANYPENIDPW 117 +V F G+EPNP + + + + R ++ ++ VGGGS D K I AA + ++ + Sbjct: 65 EVAIFDGVEPNPKDTNVRDGLAVFRREQCDIIVTVGGGSPHDCGKGIGIAATHEGDLYQY 124 Query: 118 HILQTGGKEIKSAIPMGCVLTLPATGSESNAGAVISRKTTGDKQAFHSAHVQPVFAVLDP 177 ++T + P+ V T T SE V++ T K S P ++ DP Sbjct: 125 AGIETLTNPLP---PIVAVNTTAGTASEVTRHCVLTNTETKVKFVIVSWRNLPSVSINDP 181 Query: 178 VYTYTLPPRQVANGVVDAFVHTVEQYVTKPVDAKIQDRFAEGILLTLIEDGPKALKEPEN 237 + P A +DA H VE Y++K + + D A + + + +A+ N Sbjct: 182 LLMIGKPAALTAATGMDALTHAVEAYISKDAN-PVTDAAAMQAIRLIARNLRQAVALGSN 240 Query: 238 YDVRANVMWAATQALNGLIGAGVPQDWATHMLGHELTAMHGLDHAQTLAIVLPALWNEKR 297 R + +A+ A A + H + H+L ++ + H A++LP + Sbjct: 241 LQAREYMAYASLLAGMAFNNANL---GYVHAMAHQLGGLYDMPHGVANAVLLPHVARYNL 297 Query: 298 DTKRAKLLQYAERVW-NITEGSDDERIDAAIAATRNFFEQLGVPTHLSDYGLDGSSIPAL 356 K AE + NIT S + + AIAA +G+P HL D G+ + P + Sbjct: 298 IANPEKFADIAELMGENITGLSTLDAAEKAIAAITRLSMDIGIPQHLRDLGVKETDFPYM 357 Query: 357 LKKLEEHGMTQLGENHDITLDVSRRIYEAA 386 + + G I+ A Sbjct: 358 AEMALKDG-NAFSNPRKGNEQEIAAIFRQA 386 >2BI4-A nrPDB Length = 392 Score = 381 bits (978), Expect = e-106, Method: Composition-based stats. Identities = 98/378 (25%), Positives = 157/378 (41%), Gaps = 14/378 (3%) Query: 14 FGKGAIAGLREQIPHDA--RVLITYGGGSVKKTGVLDQVLDALK--GMDVLEFGGIEPNP 69 FG+GA+ L +++ + LI ++ + GV+ +V D + G+ + G+ PNP Sbjct: 23 FGRGAVGALTDEVKRRGYQKALIVTDK-TLVQCGVVAKVTDKMDAAGLAWAIYDGVVPNP 81 Query: 70 AYETLMNAVKLVREQKVTFLLAVGGGSVLDGTKFIAAAANYPENIDPWHILQTGGKEIKS 129 + + + + +L+A+GGGS D K I +N PE D L+ K Sbjct: 82 TITVVKEGLGVFQNSGADYLIAIGGGSPQDTCKAIGIISNNPEFAD-VRSLEGLSPTNKP 140 Query: 130 AIPMGCVLTLPATGSESNAGAVISRKTTGDKQAFHSAHVQPVFAVLDPVYTYTLPPRQVA 189 ++P+ + T T +E VI+ + K H P A +D +PP A Sbjct: 141 SVPILAIPTTAGTAAEVTINYVITDEEKRRKFVCVDPHDIPQVAFIDADMMDGMPPALKA 200 Query: 190 NGVVDAFVHTVEQYVTKPVDAKIQDRFAEGILLTLIEDGPKALKEPENYDVRANVMWAAT 249 VDA H +E Y+T+ A + + + IE AL+ D A A Sbjct: 201 ATGVDALTHAIEGYITRGAWA-----LTDALHIKAIEIIAGALRGSVAGDKDAGEEMALG 255 Query: 250 QALNGLIGAGVPQDWATHMLGHELTAMHGLDHAQTLAIVLPALWNEKRDTKRAKLLQYAE 309 Q + G+ + V H + H L A + H AI+LP + D K A Sbjct: 256 QYVAGMGFSNV-GLGLVHGMAHPLGAFYNTPHGVANAILLPHVMRYNADFTGEKYRDIAR 314 Query: 310 RVWNITEG-SDDERIDAAIAATRNFFEQLGVPTHLSDYGLDGSSIPALLKKLEEHGMTQL 368 + EG S +E +AA+ A +G+P HL D G+ IPAL + + T Sbjct: 315 VMGVKVEGMSLEEARNAAVEAVFALNRDVGIPPHLRDVGVRKEDIPALAQAALDDVCTG- 373 Query: 369 GENHDITLDVSRRIYEAA 386 G + TL+ +Y A Sbjct: 374 GNPREATLEDIVELYHTA 391 >1VLJ-A nrPDB Length = 407 Score = 371 bits (952), Expect = e-103, Method: Composition-based stats. Identities = 140/398 (35%), Positives = 222/398 (55%), Gaps = 17/398 (4%) Query: 1 MNNFNLHTPTRILFGKGAIAGLREQIPHDA--RVLITYGGGSVKKTGVLDQVLDALK--G 56 M NF H PT+I+FG+G I + E+I + +VL YGGGS+KK GV DQV+D+LK G Sbjct: 13 MENFVFHNPTKIVFGRGTIPKIGEEIKNAGIRKVLFLYGGGSIKKNGVYDQVVDSLKKHG 72 Query: 57 MDVLEFGGIEPNPAYETLMNAVKLVREQKVTFLLAVGGGSVLDGTKFIAAAANYPENIDP 116 ++ +E G++PNP + AV++ +++KV +L VGGGSV+D K +AA A Y +I Sbjct: 73 IEWVEVSGVKPNPVLSKVHEAVEVAKKEKVEAVLGVGGGSVVDSAKAVAAGALYEGDI-- 130 Query: 117 WHILQTGGKEIKSAIPMGCVLTLPATGSESNAGAVISRKTTGDKQAFHSAHVQPVFAVLD 176 W G +I+ A+P+ VLT+ ATG+E N AVI+ + T +K S + P +++D Sbjct: 131 WDAF-IGKYQIEKALPIFDVLTISATGTEMNGNAVITNEKTKEKYGVSSKALYPKVSIID 189 Query: 177 PVYTYTLPPRQVANGVVDAFVHTVEQYVTKPVDAKIQDRFAEGILLTLIEDGPKALKEPE 236 P +TLP Q G VDA H +E Y +I + AEG + T+++ + +++P+ Sbjct: 190 PSVQFTLPKEQTVYGAVDAISHILEYYFDGS-SPEISNEIAEGTIRTIMKMTERLIEKPD 248 Query: 237 NYDVRANVMWAATQALNGLIGAGVP-QDWATHMLGHELTAMHGLDHAQTLAIVLPALWNE 295 +Y+ RAN+ W+AT ALNG + G +WA H + H L+A++ + H LAIV PA Sbjct: 249 DYEARANLAWSATIALNGTMAVGRRGGEWACHRIEHSLSALYDIAHGAGLAIVFPAWMKY 308 Query: 296 KRDTKRAKLLQYAERVWNITEGSDDERIDAAIAATRNFFEQLGVPTHLSDYGLDGSSIPA 355 A+ ++A++++ EG +E I I A +N+ +++G P L D G+ I Sbjct: 309 VYRKNPAQFERFAKKIFGF-EGEGEELILKGIEAFKNWLKKVGAPVSLKDAGIPEEDIDK 367 Query: 356 -------LLKKLEEHGMTQLGENHDITLDVSRRIYEAA 386 L++K + LG + + R I + A Sbjct: 368 IVDNVMLLVEKNLKPKGASLGRIMVLEREDVREILKLA 405 >3ZDR-A nrPDB Length = 433 Score = 359 bits (921), Expect = 1e-99, Method: Composition-based stats. Identities = 102/420 (24%), Positives = 174/420 (41%), Gaps = 46/420 (10%) Query: 1 MNNFNLHTPTRILFGKGAIAGLREQIPHDARVLITYGGGSVKKTGVLDQVLDALKGM-DV 59 MN P +I F K A+ L ++P +R I G + K G +D+VL L+ D Sbjct: 22 MNMQWFKVPPKIYFEKNAVQYL-AKMPDISRAFIVTDPG-MVKLGYVDKVLYYLRRRPDY 79 Query: 60 LE---FGGIEPNPAYETLMNAVKLVREQKVTFLLAVGGGSVLDGTKFIAAAANYP----- 111 + F +EP+P+ ET+M V ++R + ++A+GGGS +D K + +P Sbjct: 80 VHSEIFSEVEPDPSIETVMKGVDMMRSFEPDVIIALGGGSPMDAAKAMWLFYEHPTADFN 139 Query: 112 ----ENID----PWHILQTGGKEIKSAIPMGCVLTLPATGSESNAGAVISRKTTGDKQAF 163 + +D + + G K AIP T TGSE + AVI+ K T K Sbjct: 140 ALKQKFLDIRKRVYKYPKLGQKAKFVAIP-----TTSGTGSEVTSFAVITDKKTNIKYPL 194 Query: 164 HSAHVQPVFAVLDPVYTYTLPPRQVANGVVDAFVHTVEQYVTKPVDAKIQDRFAEGILLT 223 + P A++DP + T+P A+ +D H +E YV+ + D A + Sbjct: 195 ADYELTPDVAIVDPQFVMTVPKHVTADTGMDVLTHAIEAYVSNMAN-DYTDGLAMKAIQL 253 Query: 224 LIEDGPKALKEPENYDVRANVMWAATQALNGLIGAGVPQDWATHMLGHELTAMHGLDHAQ 283 + E P+A + + R + A+T A A + H L H+L A + H + Sbjct: 254 VFEYLPRAYQNGADELAREKMHNASTIAGMAFANAFL---GINHSLAHKLGAEFHIPHGR 310 Query: 284 TLAIVLPAL--WNEKRDTKRAKL---------LQYAE--RVWNITEGSDDERIDAAIAAT 330 I++P + +N + K +YAE R+ + + +E +++ + A Sbjct: 311 ANTILMPHVIRYNAAKPKKFTAFPKYEYFKADQRYAEIARMLGLPARTTEEGVESLVQAI 370 Query: 331 RNFFEQLGVPTHLSDYGLDGSSIPALLKKLE----EHGMTQLGENHDITLDVSRRIYEAA 386 +QL +P + G+ + ++KL E T + IY A Sbjct: 371 IKLAKQLDMPLSIEACGVSKQEFESKVEKLAELAFEDQCT-TANPKLPLVSDLVHIYRQA 429 >3OX4-A nrPDB Length = 383 Score = 346 bits (887), Expect = 9e-96, Method: Composition-based stats. Identities = 89/392 (22%), Positives = 159/392 (40%), Gaps = 16/392 (4%) Query: 1 MNNFNLHTPTRILFGKGAIAGLREQIPHDA--RVLITYGGGSVKKTGVLDQVLDALK--G 56 M + + P G+G++ + + LI + K+GV+ QV D LK G Sbjct: 1 MASSTFYIPFVNEMGEGSLEKAIKDLNGSGFKNALIVSDAF-MNKSGVVKQVADLLKAQG 59 Query: 57 MDVLEFGGIEPNPAYETLMNAVKLVREQKVTFLLAVGGGSVLDGTKFIAAAANYPENIDP 116 ++ + G+ PNP ++ +K++++ F++++GGGS D K IA A + Sbjct: 60 INSAVYDGVMPNPTVTAVLEGLKILKDNNSDFVISLGGGSPHDCAKAIALVATNGGEVKD 119 Query: 117 WHILQTGGKEIKSAIPMGCVLTLPATGSESNAGAVISRKTTGDKQAFHSAHVQPVFAVLD 176 + + K K A+P+ + T T SE +I+ + K A HV P+ +V D Sbjct: 120 YEGID---KSKKPALPLMSINTTAGTASEMTRFCIITDEVRHVKMAIVDRHVTPMVSVND 176 Query: 177 PVYTYTLPPRQVANGVVDAFVHTVEQYVTKPVDAKIQDRFAEGILLTLIEDGPKALKEPE 236 P+ +P A +DA H E Y + I D A + ++ A + Sbjct: 177 PLLMVGMPKGLTAATGMDALTHAFEAY-SSTAATPITDACALKAASMIAKNLKTACDNGK 235 Query: 237 NYDVRANVMWAATQALNGLIGAGVPQDWATHMLGHELTAMHGLDHAQTLAIVLPAL--WN 294 + R + +A A A + H + H+L + L H A++LP + +N Sbjct: 236 DMPAREAMAYAQFLAGMAFNNASL---GYVHAMAHQLGGYYNLPHGVCNAVLLPHVLAYN 292 Query: 295 EKRDTKRAKLLQYAERVWNITEGSDDERIDAAIAATRNFFEQLGVPTHLSDYGLDGSSIP 354 R K + A + +I D E +A I A R+ +G+P +L++ G +P Sbjct: 293 ASVVAGRLKDVGVAMGL-DIANLGDKEGAEATIQAVRDLAASIGIPANLTELGAKKEDVP 351 Query: 355 ALLKKLEEHGMTQLGENHDITLDVSRRIYEAA 386 L + L ++ +A Sbjct: 352 LLADHALKDACA-LTNPRQGDQKEVEELFLSA 382 >3IV7-A nrPDB Length = 364 Score = 256 bits (654), Expect = 1e-68, Method: Composition-based stats. Identities = 85/394 (21%), Positives = 139/394 (35%), Gaps = 54/394 (13%) Query: 1 MNN---FNLHT-PTRILFGKG-AIAGLREQIPHDA--RVLITYGGGSVKKT-GVLDQVLD 52 MNN FN T P +++FG G + A L++++ +V++ G + V ++ Sbjct: 2 MNNSLAFNHDTLPQKVMFGYGKSSAFLKQEVERRGSAKVMVIAGEREMSIAHKVASEIEV 61 Query: 53 ALKGMDVLEFGGIEPNPAYETLMNAVKLVREQKVTFLLAVGGGSVLDGTKFIAAAANYPE 112 A+ +V+ IE A + + ++ L+ VGGGS + K IA Sbjct: 62 AIWHDEVVMHVPIE------VAERARAVATDNEIDLLVCVGGGSTIGLAKAIA------- 108 Query: 113 NIDPWHILQTGGKEIKSAIPMGCVLTLPATGSESNAGAVISRKTTGDKQAFHSAHVQPVF 172 + +A+P+ + T T + S A V K V P Sbjct: 109 --------------MTTALPIVAIPT---TYAGSEATNVWGLTEAARKTTGVDLKVLPET 151 Query: 173 AVLDPVYTYTLPPRQVANGVVDAFVHTVEQYVTKPVDAKIQDRFAEGILLTLIEDGPKAL 232 + D T +LP ++ H ++ D AEG + L + PK + Sbjct: 152 VIYDSELTMSLPVEMSVASGLNGLAHCIDSLWGPNADPINAVLAAEG-IRALNQGLPKIV 210 Query: 233 KEPENYDVRANVMWAATQALNGLIGAGVPQDWATHMLGHELTAMHGLDHAQTLAIVLPAL 292 P + + R ++ A A AG H + H L L HAQT A VLP + Sbjct: 211 ANPHSIEGRDEALYGAYLAAVSFASAG---SGLHHKICHTLGGTFNLPHAQTHATVLPYV 267 Query: 293 WNEKRDTKRAKLLQYAERVWNITEGSDDERIDAAIAATRNFFEQLGVPTHLSDYGLDGSS 352 + + D A+ + + P LSDYG + S Sbjct: 268 L----------AFNAGDAPEAERRAAAAFGTDTALEGLQRLRLSVNAPKRLSDYGFEASG 317 Query: 353 IPALLKKLEEHGMTQLGENHDITLDVSRRIYEAA 386 I + E +T + R+ EAA Sbjct: 318 IAEAVDVTLEKV--PANNPRPVTRENLSRLLEAA 349 >5K8C-A nrPDB Length = 358 Score = 110 bits (274), Expect = 1e-24, Method: Composition-based stats. Identities = 63/378 (16%), Positives = 136/378 (35%), Gaps = 36/378 (9%) Query: 1 MNNFNLHTPTRILFGKGAIAGLREQIPHDAR------VLITYGGGSVKKTGVLDQVLDAL 54 M+ N +++FG+G+ L + + + V + G + + Sbjct: 3 MSFKNFKVVEKMIFGRGSFVQLDDVLAAQRKADDDFVVFLVDD----VHQGKPLEARIPV 58 Query: 55 KGMDVLEFGGIEPNPA---YETLMNAVKLVREQKVTFLLAVGGGSVLDGTKFIAAAANYP 111 K D+L + ++ P+ + L V+ + ++ +GGGS +D K ++ P Sbjct: 59 KAQDLLIWVNVDEEPSTIQIDALTEQVQAFNGKLPVSVVGLGGGSTMDVAKAVSLMLTNP 118 Query: 112 ENIDPWHILQTGGKEIKSAIPMGCVLTLPATGSESNAGAVISRKTTGDKQAFHSAHVQPV 171 + K A+ + T+ TG+E++ AV+ K +S + Sbjct: 119 GGSAMYQGWDLI---KKPAVHHIGIPTISGTGAEASRTAVLCGPVR--KLGLNSDYTVFD 173 Query: 172 FAVLDPVYTYTLPPRQVANGVVDAFVHTVEQYVTKPVDAKIQDRFAEGILLTLIEDGPKA 231 ++D + Q +D ++H VE ++ + +AE + D + Sbjct: 174 QIIMDSELIDGVETDQWFYTGMDCYIHCVESLEGTFLN-EFSKAYAEKAM-----DLCRQ 227 Query: 232 LKEPENYDVRANVMWAATQALNGLIGAGVPQDWATHMLGHELTAMHGLDHAQTLAIVLPA 291 + ++ + +M A+ G + Q A H + + L+ + G H I Sbjct: 228 VYLEDHPEKDDKLMMASF---MGGMSIAYSQVGACHAVSYGLSYILGYHHGIGNCIAF-D 283 Query: 292 LWNEKRDTKRAKLLQYAERV-WNITEGSDDERIDAAIAATRNFFEQLGVPTHLSDYGLDG 350 + E A+ ++ + + + D IA + +G P + YG Sbjct: 284 VLEEFYPEGVAEFRLMMKKHNITLPKNICKDLPDETIAKMVAVTKSMG-PLWANVYG--- 339 Query: 351 SSIPALLKKLEEHGMTQL 368 P +K+ + +T L Sbjct: 340 ---PTWEEKVTDEMLTAL 354 >1JPU-A nrPDB Length = 370 Score = 73.7 bits (179), Expect = 1e-13, Method: Composition-based stats. Identities = 69/402 (17%), Positives = 131/402 (32%), Gaps = 70/402 (17%) Query: 5 NLHTPTRILFGKGAIAGLREQIPHDA-RVLITYGGGSVKKTG--VLDQVLDALKGMDVLE 61 +P + + GK I + + + ++ K G +++++ + + Sbjct: 6 VFISPAKYVQGKNVITKIANYLEGIGNKTVVIADEIVWKIAGHTIVNELKKGNIAAEEVV 65 Query: 62 FGGIEPNPAYETLMNAVKLVREQKVTFLLAVGGGSVLDGTKFIAAAANYPENIDPWHILQ 121 F G + + + R+ + ++ VGGG LD K +A + +D + Sbjct: 66 FSG---EASRNEVERIANIARKAEAAIVIGVGGGKTLDTAKAVA------DELDAY---- 112 Query: 122 TGGKEIKSAIPMGCVLTLPATGSESNAGAVISRKTTGDKQAFHSAHVQPVFAVLDPVYTY 181 + V T +T + ++A +VI G +++ P ++D Sbjct: 113 -----------IVIVPTAASTDAPTSALSVIYSDD-GVFESYRFYKKNPDLVLVDTKIIA 160 Query: 182 TLPPRQVANGVVDAFVHTVEQ---------YVTKPVDAKIQDRFAEGILLTLIEDGPKAL 232 PPR +A+G+ DA VE + + + AE TL + G A Sbjct: 161 NAPPRLLASGIADALATWVEARSVIKSGGKTMAGGIPTIAAEAIAEKCEQTLFKYGKLAY 220 Query: 233 KEPEN---YDVRANVMWAAT-QALNGLIGAGVPQDWATHMLGHEL-TAMHGLDHAQTLAI 287 + + V+ A T + G G+ A H L +H L H + +A Sbjct: 221 ESVKAKVVTPALEAVVEANTLLSGLGFESGGLAAAHAIHNGFTALEGEIHHLTHGEKVA- 279 Query: 288 VLPALWNEKRDTKRAKLLQYAERVWNITEGSDDERIDAAIAATRNFFEQLGVPTHLSDYG 347 + + + +E I + L +P L D Sbjct: 280 -----------------------FGTLVQLALEEHSQQEIERYIELYLCLDLPVTLEDIK 316 Query: 348 LD---GSSIPALLKKLEEHGMTQLGENHDITLDVSRRIYEAA 386 L I + K G T + ++T D AA Sbjct: 317 LKDASREDILKVAKAATAEGET-IHNAFNVTADDVADAIFAA 357 >1KQ3-A nrPDB Length = 376 Score = 72.9 bits (177), Expect = 2e-13, Method: Composition-based stats. Identities = 76/389 (19%), Positives = 126/389 (32%), Gaps = 68/389 (17%) Query: 9 PTRILFGKGAIAGLREQIPHDARVLITYGGGSVKKTGVLDQVLDALKGMDV--LEFGGIE 66 P R + G GAI L E++ V K + + + + V FGG Sbjct: 20 PGRYVQGAGAINILEEELSRFGERAFVVIDDFVDKNVLGENFFSSFTKVRVNKQIFGGEC 79 Query: 67 PNPAYETLMNAVKLVREQKVTFLLAVGGGSVLDGTKFIAAAANYPENIDPWHILQTGGKE 126 + E L V E++ ++ +GGG LD K +A Sbjct: 80 SDEEIERLSGLV----EEETDVVVGIGGGKTLDTAKAVAY-------------------- 115 Query: 127 IKSAIPMGCVLTLPATGSESNAGAVISRKTTGDKQAFHSAHVQPVFAVLDPVYTYTLPPR 186 K P+ V T+ +T + +A +VI K+ P ++D P R Sbjct: 116 -KLKKPVVIVPTIASTDAPCSALSVIYTPNGEFKRYLFLPRN-PDVVLVDTEIVAKAPAR 173 Query: 187 QVANGVVDAFVHTVEQYVTKPVDAK---------IQDRFAEGILLTLIEDG---PKALKE 234 + G+ DA E K A A TL+E G ++++E Sbjct: 174 FLVAGMGDALATWFEAESCKQKYAPNMTGRLGSMTAYALARLCYETLLEYGVLAKRSVEE 233 Query: 235 PENYDVRANVMWAAT-QALNGLIGAGVPQDWATHMLGHELTAMHGLDHAQTLAIVLPALW 293 ++ A T + G G+ A H L H H + +AI Sbjct: 234 KSVTPALEKIVEANTLLSGLGFESGGLAAAHAIHNGLTVLENTHKYLHGEKVAI------ 287 Query: 294 NEKRDTKRAKLLQYAERVWNITEGSDDERIDAAIAATRNFFEQLGVPTHLSDYGLDG--- 350 + ++ I +F E++G+PT L++ GLDG Sbjct: 288 ------------------GVLASLFLTDKPRKMIEEVYSFCEEVGLPTTLAEIGLDGVSD 329 Query: 351 SSIPALLKKLEEHGMTQLGENHDITLDVS 379 + + +K + T E +T Sbjct: 330 EDLMKVAEKACDKNETIHNEPQPVTSKDV 358 >5ZXL-A nrPDB Length = 367 Score = 63.3 bits (152), Expect = 2e-10, Method: Composition-based stats. Identities = 64/378 (16%), Positives = 119/378 (31%), Gaps = 68/378 (17%) Query: 7 HTPTRILFGKGAIAGLREQIPHDARVLITYGGGSV---KKTGVLDQVLDALKGMDVLEFG 63 +P + + G I L E + A + G V ++ V DA +++ FG Sbjct: 6 QSPGKYIQGADVINRLGEYLKPLAERWLVVGDKFVLGFAQSTVEKSFKDAGLVVEIAPFG 65 Query: 64 GIEPNPAYETLMNAVKLVREQKVTFLLAVGGGSVLDGTKFIAAAANYPENIDPWHILQTG 123 G + + + + +L +GGG LD K +A Sbjct: 66 G---ECSQNEIDRLRGIAETAQCGAILGIGGGKTLDTAKALAHFM--------------- 107 Query: 124 GKEIKSAIPMGCVLTLPATGSESNAGAVI-SRKTTGDKQAFHSAHVQPVFAVLDPVYTYT 182 +P+ T+ +T + +A +VI + + D+ P ++D Sbjct: 108 ------GVPVAIAPTIASTDAPCSALSVIYTDEGEFDRYLLLP--NNPNMVIVDTKIVAG 159 Query: 183 LPPRQVANGVVDAFVHTVEQ---------YVTKPVDAKIQDRFAEGILLTLIEDGPKALK 233 P R +A G+ DA E + + AE TL+E+G KA+ Sbjct: 160 APARLLAAGIGDALATWFEARACSRSGATTMAGGKCTQAALALAELCYNTLLEEGEKAML 219 Query: 234 EPENY---DVRANVMWA-ATQALNGLIGAGVPQDWATHMLGHELTAMHGLDHAQTLAIVL 289 E + V+ A + G G+ A H + H H + +A Sbjct: 220 AAEQHVVTPALERVIEANTYLSGVGFESGGLAAAHAVHNGLTAIPDAHHYYHGEKVA--- 276 Query: 290 PALWNEKRDTKRAKLLQYAERVWNITEGSDDERIDAAIAATRNFFEQLGVPTHLSDYGLD 349 +T+ + I +G+P L+ + Sbjct: 277 ---------------------FGTLTQLVLENAPVEEIETVAALSHAVGLPITLAQLDI- 314 Query: 350 GSSIPALLKKLEEHGMTQ 367 +PA ++ + E + Sbjct: 315 KEDVPAKMRIVAEAACAE 332 >5FB3-A nrPDB Length = 338 Score = 62.9 bits (151), Expect = 3e-10, Method: Composition-based stats. Identities = 51/278 (18%), Positives = 91/278 (32%), Gaps = 50/278 (17%) Query: 6 LHTPTRILFGKGAIAGLREQIPHDARVLITYGGGSVKKTGVLDQVLDALK-GMDVLEFGG 64 P I+FG GA+ E IP RVLI G S +K ++V + LK +++ + Sbjct: 7 FEVPRTIIFGPGALEKTPEVIPPSGRVLIITGKSSTRK--YAERVAELLKQNCEIISYDQ 64 Query: 65 IEPNPAYETLMNAVKLVREQKVTFLLAVGGGSVLDGTKFIAAAANYPENIDPWHILQTGG 124 +E + + ++ +GGG LD K + P Sbjct: 65 VE--------------LEKPGFDLVIGIGGGRPLDMAKVYSYIHKKP------------- 97 Query: 125 KEIKSAIPMGCVLTLPATGSESNAGAV-ISRKTTGDKQAFHSAHVQPVFAVLDPVYTYTL 183 AIP A+ + V S K S+ PV + D + Sbjct: 98 ---FVAIP------TSASHDGIASPYVSFSLTQRFSKYGKISSS--PVAIIADTSIILSA 146 Query: 184 PPRQVANGVVDAFVHTVEQYVTKPVDAKIQDRFAEGILLTLIEDGPKALKEPENYD--VR 241 P R + G+ D + + + ++E + A+ + +R Sbjct: 147 PSRLLKAGIGDLLGKIIAVRDWQLAHRLKGEEYSEYAAHLSLTSYKIAVGNAQKIKNFIR 206 Query: 242 ANVMWAATQA------LNGLIGAGVPQDWATHMLGHEL 273 + +A G+ G+ P + H+ H + Sbjct: 207 EEDVRVLVKALIGCGVAMGIAGSSRPCSGSEHLFAHAI 244 >4MCA-A nrPDB Length = 367 Score = 60.6 bits (145), Expect = 1e-09, Method: Composition-based stats. Identities = 58/366 (15%), Positives = 115/366 (31%), Gaps = 63/366 (17%) Query: 7 HTPTRILFGKGAIAGLREQIPHDA-RVLITYGGGSVKKTGVLDQVLDALKGMDVLEFGGI 65 +P + + G A+A + + A L+ +K G D ++ +L+ V + Sbjct: 6 QSPGKYIQGANALAAVGQYAKSLADHYLVIADDFVMKLAG--DTLMGSLQQHGVKHHAAL 63 Query: 66 EPNPAYETLMNAVKL-VREQKVTFLLAVGGGSVLDGTKFIAAAANYPENIDPWHILQTGG 124 ++ + ++ ++ VGGG LD K IA Sbjct: 64 FNGECCHKEIDRLGRELKAHGCRGVIGVGGGKTLDTAKAIAHYQQ--------------- 108 Query: 125 KEIKSAIPMGCVLTLPATGSESNAGAVISRKTTGDKQAFHSAHVQPVFAVLDPVYTYTLP 184 +P+ + T+ +T + ++A +VI + + P V+D P Sbjct: 109 ------LPVVLIPTIASTDAPTSALSVIYTEQGEFAEYLIYPRN-PDMVVMDVAIIAKAP 161 Query: 185 PRQVANGVVDAFV------HTVEQYVTKPVDAKIQDRFAEGILL----TLIEDGPK--AL 232 R + G+ DA + T K L L E A+ Sbjct: 162 VRLLVAGMGDALSTYFEAQACFDAQATSMAGGKSTLAALSLARLCYDTLLAEGVKAKLAV 221 Query: 233 KEPENYDVRANVMWA-ATQALNGLIGAGVPQDWATHMLGHELTAMHGLDHAQTLAIVLPA 291 + + ++ A + G +G+ A H L H L H + +A Sbjct: 222 EAGVVTEAVERIIEANTYLSGIGFESSGLAAAHAIHNGFTVLEECHHLYHGEKVA----- 276 Query: 292 LWNEKRDTKRAKLLQYAERVWNITEGSDDERIDAAIAATRNFFEQLGVPTHLSDYGLDGS 351 + + A I F ++G+P L++ G+ G Sbjct: 277 -------------------FGTLAQLVLQNSPMAQIETVLAFCHRIGLPITLAEMGVSGD 317 Query: 352 SIPALL 357 ++ ++ Sbjct: 318 AVEKIM 323 >3UHJ-A nrPDB Length = 387 Score = 59.8 bits (143), Expect = 2e-09, Method: Composition-based stats. Identities = 54/297 (18%), Positives = 91/297 (30%), Gaps = 38/297 (12%) Query: 72 ETLMNAVKLVREQKVTFLLAVGGGSVLDGTKFIAAAANYPENIDPWHILQTGGKEIKSAI 131 + K+ E L+ VGGG D K +A + TG + Sbjct: 93 SEIERVRKVAIEHGSDILVGVGGGKTADTAKIVA--------------IDTGAR------ 132 Query: 132 PMGCVLTLPATGSESNAGAVISRKTTGDKQAFHSAHVQPVFAVLDPVYTYTLPPRQVANG 191 + T+ +T + +A AV + ++A P V+D P R + G Sbjct: 133 -IVIAPTIASTDAPCSAIAVRYTEHGVYEEALRLPRN-PDAVVVDSALVAAAPARFLVAG 190 Query: 192 VVDAFVHTVEQ---YVTKPVDAKIQDRFAEGILLTLIEDGPKALKEPENYDVRANVMWAA 248 + DA E ++ + A + + L A Sbjct: 191 IGDALSTWFEARSNIESRTDNYVAGGFPATEAGMAIARHCQDVLTRDAVKAKIAVEAGLL 250 Query: 249 TQALNGLIGAGVPQDWATHMLGHELTAMHGLDHAQTLAIVLPALWNEKRDTKRAKLLQYA 308 T A+ +I A +A HG+ T VL + Sbjct: 251 TPAVENIIEANTLLSGLGFENC-GCSAAHGIHDGLT---VLEEVHGY--------FHGEK 298 Query: 309 ERVWNITEGSDDERIDAAIAATRNFFEQLGVPTHLSDYGLDGSSIPALLKKLEEHGM 365 + + R A I A F +G+PT L+D G+ +PA + ++ E Sbjct: 299 VAFGTLCLLMLENRDRAEIEAMIRFCRSVGLPTKLADLGI-VDDVPAKIGRVAEAAC 354 >5XN8-A nrPDB Length = 365 Score = 58.3 bits (139), Expect = 6e-09, Method: Composition-based stats. Identities = 64/395 (16%), Positives = 124/395 (31%), Gaps = 64/395 (16%) Query: 7 HTPTRILFGKGAIAGLREQIPHDARVL-ITYGGGSVKKTGVLDQVLDALKGMDVLEFGG- 64 +P + L G A + A + +K G D+VL+ L D+ Sbjct: 6 QSPGKYLQGPDASTLFGAYAKNLAESFFVIADDFVMKLAG--DKVLNGLHSHDISLHAER 63 Query: 65 IEPNPAYETLMNAVKLVREQKVTFLLAVGGGSVLDGTKFIAAAANYPENIDPWHILQTGG 124 ++ + + ++++ ++ VGGG LD K I Sbjct: 64 FNGECSHVEIRRLIAILKQHGCRGVVGVGGGKTLDTAKAIGYYQK--------------- 108 Query: 125 KEIKSAIPMGCVLTLPATGSESNAGAVISRKTTGDKQAFHSAHVQPVFAVLDPVYTYTLP 184 +P+ + T+ +T + ++A +VI + ++ P V+D P Sbjct: 109 ------LPVVVIPTIASTDAPTSALSVIYTEAGEFEEYLIYPKN-PDMVVMDTAIIAKAP 161 Query: 185 PRQVANGVVDAFVHTVEQ---------YVTKPVDAKIQDRFAEGILLTLIEDGPKA---L 232 R + +G+ DA E + + A TL+ +G KA Sbjct: 162 VRLLVSGMGDALSTWFEAKACYDARATSMAGGQSTEAALSLARLCYDTLLAEGEKARLAA 221 Query: 233 KEPENYDVRANVMWA-ATQALNGLIGAGVPQDWATHMLGHELTAMHGLDHAQTLAIVLPA 291 + D ++ A + G +G+ A H L H L H + +A Sbjct: 222 QAGVVTDALERIIEANTYLSGIGFESSGLAAAHAIHNGFTILEECHHLYHGEKVA----- 276 Query: 292 LWNEKRDTKRAKLLQYAERVWNITEGSDDERIDAAIAATRNFFEQLGVPTHLSDYGLDGS 351 + + I F E++G+P L+ G+ Sbjct: 277 -------------------FGTLAQLVLQNSPMEEIETVLGFCEKVGLPVTLAQMGV-KE 316 Query: 352 SIPALLKKLEEHGMTQLGENHDITLDVSRRIYEAA 386 I + + + + H++ V+ AA Sbjct: 317 GIDDKIAAVAKATCAEGETIHNMPFAVTPEQVHAA 351 >1TA9-A nrPDB Length = 450 Score = 52.5 bits (124), Expect = 3e-07, Method: Composition-based stats. Identities = 58/308 (18%), Positives = 108/308 (35%), Gaps = 62/308 (20%) Query: 6 LHTPTRILFGKGAI--AGLREQIPHDARVLITYGGGSVKKTGVLDQVLDAL--KGMDV-- 59 +P + + G+ A + + + ++ ++++D+L GM V Sbjct: 66 FTSPQKYVQGRHAFTRSYMYVKKWATKSAVVLADQNVWNIC--ANKIVDSLSQNGMTVTK 123 Query: 60 LEFGGIEPNPAYETLMNAVKLVREQKVT---FLLAVGGGSVLDGTKFIAAAANYPENIDP 116 L FGG E + + +R+Q ++ VGGG +D K+IA + N Sbjct: 124 LVFGG-------EASLVELDKLRKQCPDDTQVIIGVGGGKTMDSAKYIAHSMN------- 169 Query: 117 WHILQTGGKEIKSAIPMGCVLTLPATGSESNAGAVI-SRKTTGDKQAFHSAHVQPVFAVL 175 +P T ++ + +++ +VI + K +F + P + Sbjct: 170 --------------LPSIICPTTASSDAATSSLSVIYTPDGQFQKYSF--YPLNPNLIFI 213 Query: 176 DPVYTYTLPPRQVANGVVDAFVHTVEQYVTKPVDAKIQDRFAEGILLTLIEDGPKALKE- 234 D P R + +G+ DA VE T+ V FA G+ +A K+ Sbjct: 214 DTDVIVRAPVRFLISGIGDALSTWVE---TESVIRSNSTSFAGGVASIAGRYIARACKDT 270 Query: 235 --------------PENYDVRANVMWAATQ-ALNGLIGAGVPQDWATH-MLGHELTAMHG 278 + NV+ A T + G G+ A H + +H Sbjct: 271 LEKYALSAILSNTRGVCTEAFENVVEANTLMSGLGFENGGLAAAHAIHNGMTAIHGPVHR 330 Query: 279 LDHAQTLA 286 L H + +A Sbjct: 331 LMHGEKVA 338 >1XAI-A nrPDB Length = 354 Score = 51.7 bits (122), Expect = 5e-07, Method: Composition-based stats. Identities = 47/289 (16%), Positives = 90/289 (31%), Gaps = 39/289 (13%) Query: 12 ILFGKGAIAGLREQIPHDARVLITYGGGSVKKTGVLDQVLDALKGMDV--LEFGGIEPNP 69 I GAI + + + + ++ D L +V + E Sbjct: 14 IYVEHGAIKYIGTYLNQFDQSFLLID--EYVNQYFANKFDDILSYENVHKVIIPAGEKTK 71 Query: 70 AYETLMNAVKLVREQKVT---FLLAVGGGSVLDGTKFIAAAANYPENIDPWHILQTGGKE 126 +E ++ + VT ++AVGGG+ D F+AA Sbjct: 72 TFEQYQETLEYILSHHVTRNTAIIAVGGGATGDFAGFVAA-------------------T 112 Query: 127 IKSAIPMGCVLTLPATGSESNAGAVISRKTTGDKQAFHSAHVQPVFAVLDPVYTYTLPPR 186 + + V T S G V G P + D + TLP + Sbjct: 113 LLRGVHFIQVPTTILAHDSSVGGKVGINSKQGKNLIGAFYR--PTAVIYDLDFLKTLPFK 170 Query: 187 QVANGVVDAFVHTVEQYVTKPVDAKIQDRFAEGILLTLIEDGPKALKEPENYDVRANVMW 246 Q+ +G + + H + + I+ F + +L + K + + + V Sbjct: 171 QILSGYAEVYKHAL--LNGESATQDIEQHFKDREILQSLNGMDKYIAKGIETKLDIVVAD 228 Query: 247 AATQALNGLIGAGVPQDWATHMLGHELTAMHGLDHAQTLAIVLPALWNE 295 Q + + G H GH + H + H A+++ ++ Sbjct: 229 EKEQGVRKFLNLG-------HTFGHAVEYYHKIPHG--HAVMVGIIYQF 268 >4RGQ-A nrPDB Length = 368 Score = 43.6 bits (101), Expect = 1e-04, Method: Composition-based stats. Identities = 49/353 (13%), Positives = 108/353 (30%), Gaps = 65/353 (18%) Query: 8 TPTRILFGKGAIAGLREQIP--HDARVLITYGGGSVKKTGVLDQVLDALKGMDVLEFGGI 65 TP + GAI + E + + L+ G + K D++ + I Sbjct: 38 TPRYTIIEDGAINKIEEILKKLNLKNPLVITGKNTKKYCRFF---------YDIVYYDEI 88 Query: 66 EPNPAYETLMNAVKLVREQKVTFLLAVGGGSVLDGTKFIAAAANYPENIDPWHILQTGGK 125 N E L + ++ +GGG +D K++A Sbjct: 89 LNNLEIE-------LKKYTAYDCVIGIGGGRSIDTGKYLAY------------------- 122 Query: 126 EIKSAIPMGCVLTLPATGSESNAGAVISRKTTGDKQAFHSAHVQPVFAVLDPVYTYTLPP 185 K IP V T + I+ +Q P+ + D P Sbjct: 123 --KLGIPFISVPTTA-------SNDGIASPIVSIRQP-SFMVDAPIAIIADTEIIKKSPR 172 Query: 186 RQVANGVVDAFVHTVEQYVTKPVDAKIQDRFAEGILL---TLIEDGPKALKEPENYDVRA 242 R ++ G+ D + K + ++++E + T+ ++ + + + Sbjct: 173 RLLSAGMGDIVSNITAVLDWKLAYKEKGEKYSESSAIFSKTIAKELISYVLNSDLSEYHN 232 Query: 243 NVMWAATQALNGLIGAG--VPQDWATHMLGHELTAMHGLDHAQTLAIVLPALWNEKRDTK 300 ++ A + + A P + H+ H L L +N ++ Sbjct: 233 KLVKALVGSGIAIAIANSSRPASGSEHLFSHALDK-------------LKEEYNLNINSL 279 Query: 301 RAKLLQYAERVWNITEGSDDERIDAAIAATRNFFEQLGVPTHLSDYGLDGSSI 353 + + + +++++ + +++ PT + G D I Sbjct: 280 HGEQCGIGTIMMSYLHEKENKKLSGLHEKIKMSLKKVDAPTTAKELGFDEDII 332 >4RFL-A nrPDB Length = 371 Score = 43.3 bits (100), Expect = 2e-04, Method: Composition-based stats. Identities = 49/353 (13%), Positives = 108/353 (30%), Gaps = 65/353 (18%) Query: 8 TPTRILFGKGAIAGLREQIP--HDARVLITYGGGSVKKTGVLDQVLDALKGMDVLEFGGI 65 TP + GAI + E + + L+ G + K D++ + I Sbjct: 41 TPRYTIIEDGAINKIEEILKKLNLKNPLVITGKNTKKYCRFF---------YDIVYYDEI 91 Query: 66 EPNPAYETLMNAVKLVREQKVTFLLAVGGGSVLDGTKFIAAAANYPENIDPWHILQTGGK 125 N E L + ++ +GGG +D K++A Sbjct: 92 LNNLEIE-------LKKYTAYDCVIGIGGGRSIDTGKYLAY------------------- 125 Query: 126 EIKSAIPMGCVLTLPATGSESNAGAVISRKTTGDKQAFHSAHVQPVFAVLDPVYTYTLPP 185 K IP V T + I+ +Q P+ + D P Sbjct: 126 --KLGIPFISVPTTA-------SNDGIASPIVSIRQP-SFMVDAPIAIIADTEIIKKSPR 175 Query: 186 RQVANGVVDAFVHTVEQYVTKPVDAKIQDRFAEGILL---TLIEDGPKALKEPENYDVRA 242 R ++ G+ D + K + ++++E + T+ ++ + + + Sbjct: 176 RLLSAGMGDIVSNITAVLDWKLAYKEKGEKYSESSAIFSKTIAKELISYVLNSDLSEYHN 235 Query: 243 NVMWAATQALNGLIGAG--VPQDWATHMLGHELTAMHGLDHAQTLAIVLPALWNEKRDTK 300 ++ A + + A P + H+ H L L +N ++ Sbjct: 236 KLVKALVGSGIAIAIANSSRPASGSEHLFSHALDK-------------LKEEYNLNINSL 282 Query: 301 RAKLLQYAERVWNITEGSDDERIDAAIAATRNFFEQLGVPTHLSDYGLDGSSI 353 + + + +++++ + +++ PT + G D I Sbjct: 283 HGEQCGIGTIMMSYLHEKENKKLSGLHEKIKMSLKKVDAPTTAKELGFDEDII 335 >3CE9-A nrPDB Length = 354 Score = 41.3 bits (95), Expect = 8e-04, Method: Composition-based stats. Identities = 49/290 (16%), Positives = 91/290 (31%), Gaps = 41/290 (14%) Query: 8 TPTRILFGKGAIAGLREQIPHD--ARVLITYGGGSVKKTGVLDQVLDALKGMDVLEFGGI 65 P + G I + + I RV + +G G + G + +++ + Sbjct: 11 IPLILEVGNNKIYNIGQIIKKGNFKRVSLYFGEGIYELFGETIEKSIKSSNIEIEAVETV 70 Query: 66 EPNPAYETLMNAVKLVREQKVTFLLAVGGGSVLDGTKFIAAAANYPENIDPWHILQTGGK 125 + E NA K+ +V L+ +GGG +D K++A Sbjct: 71 KNIDFDEIGTNAFKI--PAEVDALIGIGGGKAIDAVKYMAFL------------------ 110 Query: 126 EIKSAIPMGCVLTLPAT--GSESNAGAVISRKTTGDKQAFHSAHVQPVFAVLDPVYTYTL 183 +P V T + S A +I+ K T P V+D Sbjct: 111 ---RKLPFISVPTSTSNDGFSSPVASLLINGKRTSV------PAKTPDGIVVDIDVIKGS 161 Query: 184 PPRQVANGVVDAFVHTVEQYV----TKPVDAKIQDRFAEGILLTLIEDGPKALKEPENYD 239 P + + +G+ D + Y + + I D ++ K ++ Sbjct: 162 PEKFIYSGIGDLVSNITALYDWKFEEENHKSIIDDFAVMISKKSVNSFVRTDFKSIKDEV 221 Query: 240 VRANVMWAATQALNGL--IGAGVPQDWATHMLGHELTAMHGLDHAQTLAI 287 ++ + T + G P A H++ H L L + Q I Sbjct: 222 FLKELVDSLTMNGIAMEIAGNSSPASGAEHLISHALDKF--LPNPQLHGI 269 >5HUQ-A nrPDB Length = 433 Score = 33.6 bits (75), Expect = 0.13, Method: Composition-based stats. Identities = 29/191 (15%), Positives = 55/191 (28%), Gaps = 18/191 (9%) Query: 78 VKLVREQKVTFLLAVGGGSVLDGTKFIAAAANYPENIDPWHILQTGGKEIKSAIPMGCVL 137 ++ + F+ + +D I+ YP + + + ++ + G ++ Sbjct: 255 MEAAHKVGCDFVKELSSVPAIDCDIAISTNGGYPLDQNIYQAVKGMTAAEATNKEGGTII 314 Query: 138 TLPAT--GSESNAGAVISRKTTGDKQAFHSAHVQPVFAVLDPVYTYTLPPRQVANGVVDA 195 + G + A+ P T+P + A Sbjct: 315 MVAGARDGHGGEGFY-------HNLADVDDPKEFLDQAINTPRLK-TIPDQWTAQIFARI 366 Query: 196 FVHTVEQYVTKPVDAKIQDRFAEGILLTLIEDGPKALKEPENYDVRANVMWAATQALNGL 255 VH +V+ VD + + TL E KA R T +GL Sbjct: 367 LVHHHVIFVSDLVDPDLITNMHMELAKTLDEAMEKAY-------AREGQAAKVTVIPDGL 419 Query: 256 IGAGVPQDWAT 266 G V W+ Sbjct: 420 -GVIVKASWSH 429 >3NDA-A nrPDB Length = 377 Score = 30.6 bits (67), Expect = 1.2, Method: Composition-based stats. Identities = 20/131 (15%), Positives = 39/131 (29%), Gaps = 13/131 (9%) Query: 185 PRQVANGVVDAFVHTVEQYVTKPVDA--KIQDRFAEGILLTLIEDGPKALKEPENYDVRA 242 GV+DA+ H E+ + P ++ + + A L L+ AL+ ++ Sbjct: 65 VDLTDAGVLDAYTHHTERLKSTPSNSTLDVANAAAIQRTLALLNSYESALQSSFGAELHK 124 Query: 243 NVMWAATQALNGLIGAGVPQDWATHMLGHELTAMHGLDHA------QTLAIVLPALWNEK 296 QA + W ++ + AI WN Sbjct: 125 VDFAGEPQAAVDFVNN-----WVKRKTHDKIEKLFNEPLDPDTLLVLLNAIYFKGEWNTA 179 Query: 297 RDTKRAKLLQY 307 + + Q+ Sbjct: 180 FVKEHTEKRQF 190 >5EZ7-A nrPDB Length = 392 Score = 30.2 bits (66), Expect = 1.4, Method: Composition-based stats. Identities = 24/138 (17%), Positives = 41/138 (29%), Gaps = 23/138 (16%) Query: 246 WAATQALNGLIGAG--VPQDWATHMLGHELTAMHGLDHAQTLAIV-LPALWNEKRDTKRA 302 +A + +G G V H A+HG + AI +P W + Sbjct: 31 YATVLVESASLGGGQSVKSQGIIHGGAKY--ALHGALTGASEAIADMPRRWRACLGSDGE 88 Query: 303 KLLQ---------YAERVWNITEGSDDERIDAAIAATRNFFEQLGVPTHLSDYGLDGS-- 351 L+ Y + A+ + + +P L D G G Sbjct: 89 LDLRGVRLLSEAHYLWSPGGLAGSLTSFFASKAVRSRVEQAKGEDLPPALRDKGFKGKAY 148 Query: 352 -------SIPALLKKLEE 362 +P L+++L E Sbjct: 149 RLTEIVFDVPDLIRRLAE 166 >1NLT-A nrPDB Length = 248 Score = 30.2 bits (66), Expect = 1.5, Method: Composition-based stats. Identities = 16/79 (20%), Positives = 30/79 (37%), Gaps = 9/79 (11%) Query: 23 REQIPHDARVLITY------GGGSVKKTGVLDQVLDALKGMDVLEFGGIEPNPAYETLMN 76 +++ ++ ++L + G + G DQ D + G V P + Sbjct: 104 GKKVENERKILEVHVEPGMKDGQRIVFKGEADQAPDVIPGDVVFIVSE---RPHKSFKRD 160 Query: 77 AVKLVREQKVTFLLAVGGG 95 LV E ++ L A+ GG Sbjct: 161 GDDLVYEAEIDLLTAIAGG 179 >3LCV-B nrPDB Length = 281 Score = 30.2 bits (66), Expect = 1.8, Method: Composition-based stats. Identities = 24/129 (18%), Positives = 35/129 (27%), Gaps = 19/129 (14%) Query: 271 HELTAMHGLDHAQTLAIVLPALWNEKRDTKRAKLLQYAERVWNITEGSDDERIDAAIAAT 330 HE+ A +L L + D + ++ A S ER+ Sbjct: 65 HEIYGAFLPPSPPNYAALLRHL-DSAVDAGDDEAVRAALLRAMSVHISTRERLPHLDEFY 123 Query: 331 RNFFEQLGVPTHLSDY------------GLDGS------SIPALLKKLEEHGMTQLGENH 372 R F L P L D GL I A L + +T+L H Sbjct: 124 RELFRHLPRPNTLRDLACGLNPLAAPWMGLPAETVYIASDIDARLVGFVDEALTRLNVPH 183 Query: 373 DITLDVSRR 381 + Sbjct: 184 RTNVADLLE 192 >5GUW-B nrPDB Length = 465 Score = 29.8 bits (65), Expect = 2.1, Method: Composition-based stats. Identities = 20/86 (23%), Positives = 35/86 (40%), Gaps = 15/86 (17%) Query: 237 NYDVRANVMWAATQALNGLIGAGV--------PQDWATHMLGHELTAMH-GLDHAQTLAI 287 +Y RA +WA + +GAGV P ++ TH +LTA H + A+ Sbjct: 301 DYPNRAVALWAMGTTVMAFLGAGVWGFMHTLAPVNYYTHGT--QLTAAHGHMAFYGAYAM 358 Query: 288 VLPALWNEKRDTKRAKLLQYAERVWN 313 ++ + + +L E + N Sbjct: 359 IVMTIISYAMP----RLRGIGEAMDN 380 >4P63-A nrPDB Length = 342 Score = 29.0 bits (63), Expect = 3.1, Method: Composition-based stats. Identities = 17/74 (22%), Positives = 29/74 (39%), Gaps = 1/74 (1%) Query: 55 KGMDVLEFGGIEPNPAYETLMNAVK-LVREQKVTFLLAVGGGSVLDGTKFIAAAANYPEN 113 +G ++ F G N L + LV+E+KV ++ GG D K + Sbjct: 63 RGEEIRVFLGYTSNIISSGLREIIAWLVKEKKVDVIVTTAGGVEEDFIKSLKPFILGDWE 122 Query: 114 IDPWHILQTGGKEI 127 +D + + G I Sbjct: 123 VDDAELRKKGVNRI 136 >3THU-A nrPDB Length = 426 Score = 29.0 bits (63), Expect = 4.0, Method: Composition-based stats. Identities = 19/99 (19%), Positives = 34/99 (34%), Gaps = 3/99 (3%) Query: 289 LPALWNEKRDTKRAKLLQYAERVWNITEGSDDERIDAAIAATRNFFEQLGVPTHLSDYGL 348 LP ++ R ++ Y E + +D + Q GVP S YG+ Sbjct: 127 LP-VYQLLGGASREGVMVYGHANGTTIEDTVKVALDYQAQGYKAIRLQCGVPGMASTYGV 185 Query: 349 DGSSIPALLKKLEEHGMTQLGENHDITLDVSRRIYEAAR 387 + + T+ N L + +++AAR Sbjct: 186 SKDK--YFYEPADADLPTENIWNTSKYLRIVPELFKAAR 222 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.311 0.122 0.288 Lambda K H 0.267 0.0373 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 12,615,697 Number of Sequences: 36641 Number of extensions: 466973 Number of successful extensions: 1613 Number of sequences better than 10.0: 29 Number of HSP's better than 10.0 without gapping: 32 Number of HSP's successfully gapped in prelim test: 22 Number of HSP's that attempted gapping in prelim test: 1502 Number of HSP's gapped (non-prelim): 57 length of query: 387 length of database: 10,336,785 effective HSP length: 99 effective length of query: 288 effective length of database: 6,709,326 effective search space: 1932285888 effective search space used: 1932285888 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.5 bits) S2: 60 (27.9 bits)