BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q43866 (584 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 2AC1-A nrPDB 1123 0.0 2ADD-A nrPDB 609 e-175 3UGH-A nrPDB 431 e-121 1UYP-A nrPDB 140 1e-33 1Y4W-A nrPDB 136 2e-32 3PIG-A nrPDB 132 6e-31 3SC7-X nrPDB 105 6e-23 3U14-A nrPDB 91 1e-18 4EQV-A nrPDB 90 3e-18 5FMB-A nrPDB 65 7e-11 4FFH-A nrPDB 60 2e-09 4IED-A nrPDB 31 1.3 2Z1Q-A nrPDB 30 2.9 2IO3-A nrPDB 29 5.1 2XI1-A nrPDB 29 6.0 6CA8-A nrPDB 29 7.0 >2AC1-A nrPDB Length = 541 Score = 1123 bits (2905), Expect = 0.0, Method: Compositional matrix adjust. Identities = 541/541 (100%), Positives = 541/541 (100%) Query: 44 SPSVNQPYRTGFHFQPPKNWMNDPNGPMIYKGIYHLFYQWNPKGAVWGNIVWAHSTSTDL 103 SPSVNQPYRTGFHFQPPKNWMNDPNGPMIYKGIYHLFYQWNPKGAVWGNIVWAHSTSTDL Sbjct: 1 SPSVNQPYRTGFHFQPPKNWMNDPNGPMIYKGIYHLFYQWNPKGAVWGNIVWAHSTSTDL 60 Query: 104 INWDPHPPAIFPSAPFDINGCWSGSATILPNGKPVILYTGIDPKNQQVQNIAEPKNLSDP 163 INWDPHPPAIFPSAPFDINGCWSGSATILPNGKPVILYTGIDPKNQQVQNIAEPKNLSDP Sbjct: 61 INWDPHPPAIFPSAPFDINGCWSGSATILPNGKPVILYTGIDPKNQQVQNIAEPKNLSDP 120 Query: 164 YLREWKKSPLNPLMAPDAVNGINASSFRDPTTAWLGQDKKWRVIIGSKIHRRGLAITYTS 223 YLREWKKSPLNPLMAPDAVNGINASSFRDPTTAWLGQDKKWRVIIGSKIHRRGLAITYTS Sbjct: 121 YLREWKKSPLNPLMAPDAVNGINASSFRDPTTAWLGQDKKWRVIIGSKIHRRGLAITYTS 180 Query: 224 KDFLKWEKSPEPLHYDDGSGMWECPDFFPVTRFGSNGVETSSFGEPNEILKHVLKISLDD 283 KDFLKWEKSPEPLHYDDGSGMWECPDFFPVTRFGSNGVETSSFGEPNEILKHVLKISLDD Sbjct: 181 KDFLKWEKSPEPLHYDDGSGMWECPDFFPVTRFGSNGVETSSFGEPNEILKHVLKISLDD 240 Query: 284 TKHDYYTIGTYDRVKDKFVPDNGFKMDGTAPRYDYGKYYASKTFFDSAKNRRILWGWTNE 343 TKHDYYTIGTYDRVKDKFVPDNGFKMDGTAPRYDYGKYYASKTFFDSAKNRRILWGWTNE Sbjct: 241 TKHDYYTIGTYDRVKDKFVPDNGFKMDGTAPRYDYGKYYASKTFFDSAKNRRILWGWTNE 300 Query: 344 SSSVEDDVEKGWSGIQTIPRKIWLDRSGKQLIQWPVREVERLRTKQVKNLRNKVLKSGSR 403 SSSVEDDVEKGWSGIQTIPRKIWLDRSGKQLIQWPVREVERLRTKQVKNLRNKVLKSGSR Sbjct: 301 SSSVEDDVEKGWSGIQTIPRKIWLDRSGKQLIQWPVREVERLRTKQVKNLRNKVLKSGSR 360 Query: 404 LEVYGVTAAQADVEVLFKVRDLEKADVIEPSWTDPQLICSKMNVSVKSGLGPFGLMVLAS 463 LEVYGVTAAQADVEVLFKVRDLEKADVIEPSWTDPQLICSKMNVSVKSGLGPFGLMVLAS Sbjct: 361 LEVYGVTAAQADVEVLFKVRDLEKADVIEPSWTDPQLICSKMNVSVKSGLGPFGLMVLAS 420 Query: 464 KNLEEYTSVYFRIFKARQNSNKYVVLMCSDQSRSSLKEDNDKTTYGAFVDINPHQPLSLR 523 KNLEEYTSVYFRIFKARQNSNKYVVLMCSDQSRSSLKEDNDKTTYGAFVDINPHQPLSLR Sbjct: 421 KNLEEYTSVYFRIFKARQNSNKYVVLMCSDQSRSSLKEDNDKTTYGAFVDINPHQPLSLR 480 Query: 524 ALIDHSVVESFGGKGRACITSRVYPKLAIGKSSHLFAFNYGYQSVDVLNLNAWSMNSAQI 583 ALIDHSVVESFGGKGRACITSRVYPKLAIGKSSHLFAFNYGYQSVDVLNLNAWSMNSAQI Sbjct: 481 ALIDHSVVESFGGKGRACITSRVYPKLAIGKSSHLFAFNYGYQSVDVLNLNAWSMNSAQI 540 Query: 584 S 584 S Sbjct: 541 S 541 >2ADD-A nrPDB Length = 543 Score = 609 bits (1571), Expect = e-175, Method: Compositional matrix adjust. Identities = 281/541 (51%), Positives = 389/541 (71%), Gaps = 14/541 (2%) Query: 47 VNQPYRTGFHFQPPKNWMNDPNGPMIYKGIYHLFYQWNPKGAVWGN-IVWAHSTSTDLIN 105 + QPYRTG+HFQPP NWMNDPNGPM+Y+G+YH FYQ+NP A +G+ I+W H+ S DL+N Sbjct: 3 IEQPYRTGYHFQPPSNWMNDPNGPMLYQGVYHFFYQYNPYAATFGDVIIWGHAVSYDLVN 62 Query: 106 WDPHPPAIFPSAPFDINGCWSGSATILPNGKPVILYTGIDPKNQQVQNIAEPKNLSDPYL 165 W PAI+P+ D CWSGSATILP P +LYTG D K++QVQ++A PKNLSDP+L Sbjct: 63 WIHLDPAIYPTQEADSKSCWSGSATILPGNIPAMLYTGSDSKSRQVQDLAWPKNLSDPFL 122 Query: 166 REWKKSPLNPLMAPDAVNGINASSFRDPTTAWLGQDKKWRVIIGSKIHRRGLAITYTSKD 225 REW K P NPL+ P G+ FRDP+TAWLG D WR+++G G+A Y S D Sbjct: 123 REWVKHPKNPLITPP--EGVKDDCFRDPSTAWLGPDGVWRIVVGGDRDNNGMAFLYQSTD 180 Query: 226 FLKWEKSPEPLHYDDGSGMWECPDFFPVTRFGSNGVETSSFGEPNEILKHVLKISLDDTK 285 F+ W++ +PL D +G WECPDF+PV +NG++TS +G ++HV+K + Sbjct: 181 FVNWKRYDQPLSSADATGTWECPDFYPVPLNSTNGLDTSVYGGS---VRHVMKAGFE--G 235 Query: 286 HDYYTIGTYDRVKDKFVPDNGFKMDGTAP--RYDYGKYYASKTFFDSAKNRRILWGWTNE 343 HD+YTIGTY ++ F+P NG + G+ RYDYG++YASK+FFD AKNRR+LW W E Sbjct: 236 HDWYTIGTYSPDRENFLPQNGLSLTGSTLDLRYDYGQFYASKSFFDDAKNRRVLWAWVPE 295 Query: 344 SSSVEDDVEKGWSGIQTIPRKIWLDRSGKQLIQWPVREVERLRTKQVKNLRNKVLKSGSR 403 + S DD+EKGW+G+Q+ PR +W+DR+GKQLIQWPV E+E LR QV NL+NK LK GS Sbjct: 296 TDSQADDIEKGWAGLQSFPRALWIDRNGKQLIQWPVEEIEELRQNQV-NLQNKNLKPGSV 354 Query: 404 LEVYGVTAAQADVEVLFKVRDLEKADVIEPSWTDPQLICSKMNVSVKSGLGPFGLMVLAS 463 LE++G+ A+QADV + FK+ L++A+V++ + DPQ +C++ S + LGPFGL+ +AS Sbjct: 355 LEIHGIAASQADVTISFKLEGLKEAEVLDTTLVDPQALCNERGASSRGALGPFGLLAMAS 414 Query: 464 KNLEEYTSVYFRIFKARQNSNKYVVLMCSDQSRSSLKEDNDKTTYGAFVDINPH-QPLSL 522 K+L+E ++++FR+F+ + +Y VLMCSD SRS+++ + D T+YGAFVDI+P + +SL Sbjct: 415 KDLKEQSAIFFRVFQNQL--GRYSVLMCSDLSRSTVRSNIDTTSYGAFVDIDPRSEEISL 472 Query: 523 RALIDHSVVESFGGKGRACITSRVYPKLAIGKSSHLFAFNYGYQSVDVLNLNAWSMNSAQ 582 R LIDHS++ESFG G+ CITSR+YPK + +HLF FN G Q+V + ++AWSM +A+ Sbjct: 473 RNLIDHSIIESFGAGGKTCITSRIYPKFVNNEEAHLFVFNNGTQNVKISEMSAWSMKNAK 532 Query: 583 I 583 Sbjct: 533 F 533 >3UGH-A nrPDB Length = 546 Score = 431 bits (1107), Expect = e-121, Method: Compositional matrix adjust. Identities = 231/534 (43%), Positives = 319/534 (59%), Gaps = 13/534 (2%) Query: 52 RTGFHFQPPKNWMNDPNGPMIYKGIYHLFYQWNPKGAVWGNIVWAHSTSTDLINWDPHPP 111 RT FHFQP ++WM+DP+GP+ YKG YH FYQ+NP VWGN W H+ S DLI+W P Sbjct: 19 RTAFHFQPERSWMSDPDGPIFYKGWYHFFYQYNPDNPVWGNNTWGHTVSRDLIHWLYLPL 78 Query: 112 AIFPSAPFDINGCWSGSATILPNGKPVILYTGIDPKNQQVQNIAEPKNLSDPYLREWKKS 171 A+ +D+ G +SGSAT LP+G+ ++LYTG+ + ++ ++A P +LSDP L EW K Sbjct: 79 ALAADQWYDMQGVFSGSATCLPDGRIMMLYTGVTKEMVEMLSLAYPADLSDPLLVEWVKY 138 Query: 172 PLNPLMAPDAVNGINASSFRDPTTAWLGQDKKWRVIIGSKIHRRGLAITYTSKDFLKWEK 231 P NP+++ A G++ + FRD +T W + WR+ IG+K + G+A+ Y +KDF ++ Sbjct: 139 PGNPILS--APPGVSPTEFRDASTGWYVSNGTWRIAIGAKYNTTGIAMVYETKDFKSFKL 196 Query: 232 SPEPLHYDDGSGMWECPDFFPVTRFGSNGVETSSFGEPNEILKHVLKISLDDTKHDYYTI 291 E LH +G+WEC D +PV+ G G+ETS G +KHVLK S+D+ + DYY I Sbjct: 197 LEELLHAVPDTGLWECVDLYPVSTTGEKGLETSVNGPK---VKHVLKASIDEQQRDYYAI 253 Query: 292 GTYDRVKDKFVPDNGFKMDGTAPRYDYGKYYASKTFFDSAKNRRILWGWTNESSSVEDDV 351 GTYD +K+ PDN + G RYD+GKYYASKTF+D K RR++W WT E S D Sbjct: 254 GTYDLGTNKWTPDNPEEDVGIGLRYDWGKYYASKTFYDPKKQRRVVWAWTKELDSEVADR 313 Query: 352 EKGWSGIQTIPRKIWLD-RSGKQLIQWPVREVERLRTKQVKNLRNKVLKSGSRLEVYGVT 410 EKGW+ +QTIPR + LD ++G ++ WPV EVE LR K +GS + + T Sbjct: 314 EKGWANVQTIPRTVLLDQKTGTNVLLWPVEEVESLRLSS-KEFSKVKAGAGSVVPLDVGT 372 Query: 411 AAQADVEVLFKVRDLEKADVIEPSWTDPQLICSKMNVSVKSG-LGPFGLMVLASKNLEEY 469 A Q D+ F++ IE D C+ + + G LGPFGL+V A++NL E Sbjct: 373 ATQLDIIAEFEIDKEALEGTIE---ADMGYNCTTSGGAAERGVLGPFGLLVSATENLSEQ 429 Query: 470 TSVYFRIFKARQNSNKYVVLMCSDQSRSSLKEDNDKTTYGAFVDINPHQPLSLRALIDHS 529 T VYF I A+ + C D+SRSS D K G V + + ++R L+DHS Sbjct: 430 TPVYFYI--AKGTDGNFKTFFCLDESRSSKASDVSKQVKGFTVPVLDGEKFTMRLLVDHS 487 Query: 530 VVESFGGKGRACITSRVYPKLAIGKSSHLFAFNYGYQSVDVLNLNAWSMNSAQI 583 +VESF GR+CITSRVYP AI ++ LF FN + +L W MNSA I Sbjct: 488 IVESFAQGGRSCITSRVYPTEAIYGAAKLFLFNNATGASITASLKIWEMNSAFI 541 >1UYP-A nrPDB Length = 432 Score = 140 bits (354), Expect = 1e-33, Method: Compositional matrix adjust. Identities = 103/344 (29%), Positives = 175/344 (50%), Gaps = 43/344 (12%) Query: 51 YRTGFHFQPPKNWMNDPNGPMIYKGIYHLFYQWNPKGAVWGNIVWAHSTSTDLINWDPHP 110 ++ +HF P WMNDPNG + +KG YH+FYQ+NP+ WGNI W H+ S DL++W P Sbjct: 2 FKPNYHFFPITGWMNDPNGLIFWKGKYHMFYQYNPRKPEWGNICWGHAVSDDLVHWRHLP 61 Query: 111 PAIFPSAPFDINGCWSGSATILPNGKPVILYTGI-DPKNQQVQNIAEPKNLSDPYLREWK 169 A++P + +G +SGSA + +GK ++YT DP + + + + +S+ L ++ Sbjct: 62 VALYPDD--ETHGVFSGSA-VEKDGKMFLVYTYYRDPTHNKGEKETQCVVMSENGL-DFV 117 Query: 170 KSPLNPLMAPDAVNGINASSFRDPTTAWLGQDKKWRVIIGS-KIHRRGLAITYTSKDFLK 228 K NP+++ G +A FRDP + +WR+++GS K + G + YTS D Sbjct: 118 KYDGNPVISKPPEEGTHA--FRDPKVN--RSNGEWRMVLGSGKDEKIGRVLLYTSDDLFH 173 Query: 229 WEKSPEPLHYDDGSGMWECPDFFPVTRFGSNGVETSSFGEPNEILKHVLKISLDDTKHDY 288 W K + D+ + ECPD + R G K +L S+ T Sbjct: 174 W-KYEGAIFEDETTKEIECPD---LVRIGE---------------KDILIYSITSTNSVL 214 Query: 289 YTIGTYDRVKDKFVPDNGFKMDGTAPRYDYGKYYASKTFFDSAKNRRILWGWTNE--SSS 346 +++G K V G GT +YA++TFF + +R ++ GW + Sbjct: 215 FSMGELKEGKLN-VEKRGLLDHGT-------DFYAAQTFFGT--DRVVVIGWLQSWLRTG 264 Query: 347 VEDDVEKGWSGIQTIPRKIWLDRSGKQLIQWPVREVERLRTKQV 390 + +GW+G+ ++PR+++++ + +L PV E+ LR ++V Sbjct: 265 LYPTKREGWNGVMSLPRELYVENN--ELKVKPVDELLALRKRKV 306 >1Y4W-A nrPDB Length = 518 Score = 136 bits (343), Expect = 2e-32, Method: Compositional matrix adjust. Identities = 138/533 (25%), Positives = 216/533 (40%), Gaps = 81/533 (15%) Query: 48 NQPYRTGFHFQPPKNWMNDPNGPMIYKGIYHLFYQWNPKGAVWGNIVWAHSTSTDLINWD 107 +QPYR +HF P KNWMNDPNG + + G YHLF+Q+NP G WGNI W H+ S DL +W+ Sbjct: 4 DQPYRGQYHFSPQKNWMNDPNGLLYHNGTYHLFFQYNPGGIEWGNISWGHAISEDLTHWE 63 Query: 108 PHPPAIFPSA-PFDINGCW-SGSATILPN--------GKP--VILYTG------IDPKNQ 149 P A+ D+ + SGSA N GK V +YT P Q Sbjct: 64 EKPVALLARGFGSDVTEMYFSGSAVADVNNTSGFGKDGKTPLVAMYTSYYPVAQTLPSGQ 123 Query: 150 QVQNIAEPKNLS---DPYLREWKKSPLNPLMA-PDAVNGINASSFRDPTTAWLGQDKKWR 205 VQ + ++++ D L NP++ P + +FRDP W + +KW Sbjct: 124 TVQEDQQSQSIAYSLDDGLTWTTYDAANPVIPNPPSPYEAEYQNFRDPFVFWHDESQKWV 183 Query: 206 VIIG-SKIHRRGLAITYTSKDFLKWEKSPEPLHYDDGSGMWECPDFFPVTRFGSNG---V 261 V+ +++H+ LAI YTS + W+ E Y+ G+WECP + N V Sbjct: 184 VVTSIAELHK--LAI-YTSDNLKDWKLVSEFGPYNAQGGVWECPGLVKLPLDSGNSTKWV 240 Query: 262 ETSSF---GEPNEILKHVLKISLDDTKHDYYTIGTYDRVKDKFVPDNGFKMDGTAPRYDY 318 TS G P + Y +G +D D + + TA D+ Sbjct: 241 ITSGLNPGGPPGTVGSGTQ-----------YFVGEFDGTTFTPDADTVYPGNSTANWMDW 289 Query: 319 G-KYYASKTFFDSAKNRRILWGWTNESSSVEDDVEKGWSGIQTIPRKIWLDRSGKQ--LI 375 G +YA+ + + N + GW N + W IPR + L G + L+ Sbjct: 290 GPDFYAAAGYNGLSLNDHVHIGWMNNWQYGANIPTYPWRSAMAIPRHMALKTIGSKATLV 349 Query: 376 QWPVREVERLRTKQVKNLRNKVLKSGSRLEVYGVTAAQADVEVLFKVRDLEKADVIEPSW 435 Q P + K + + ++ K+ + + FKV Sbjct: 350 QQPQEAWSSISNK--RPIYSRTFKT-----LSEGSTNTTTTGETFKV------------- 389 Query: 436 TDPQLICSKMNVSVKSGLGPFGLMVLASKNLEEYTSVYFRIFKARQNSNKYVVLMCSDQS 495 ++ S KS F + + AS N E T V + K + + + S Sbjct: 390 --------DLSFSAKSKASTFAIALRASANFTEQTLVGYDFAKQQ-------IFLDRTHS 434 Query: 496 RSSLKEDNDKTTYGAFVDINPHQPLSLRALIDHSVVESFGGKGRACITSRVYP 548 ++ + Y + + + L +D S VE FGG+G +T++++P Sbjct: 435 GDVSFDETFASVYHGPLTPDSTGVVKLSIFVDRSSVEVFGGQGETTLTAQIFP 487 >3PIG-A nrPDB Length = 526 Score = 132 bits (331), Expect = 6e-31, Method: Compositional matrix adjust. Identities = 112/392 (28%), Positives = 171/392 (43%), Gaps = 47/392 (11%) Query: 55 FHFQPPKNWMNDPNGPMIYKGIYHLFYQWNPKGAVWGNIVWAHSTSTDLINWDPHPPAIF 114 +H W+NDPNG YKG +H+FYQ +P G WG + W H +STD++NW P Sbjct: 43 YHIASNGGWINDPNGLCFYKGRWHVFYQLHPYGTQWGPMHWGHVSSTDMLNWKREPIMFA 102 Query: 115 PSAPFDINGCWSGSATILPNGKPVILYTGIDPKNQ--------QVQNIAEPKNLSDPYLR 166 PS + +G +SGSA I NG YTG N QVQ A P N Sbjct: 103 PSLEQEKDGVFSGSAVIDDNGDLRFYYTGHRWANGHDNTGGDWQVQMTALPDN------- 155 Query: 167 EWKKSPLNPLMAPDAVNGINASSFRDPTTAWLGQDKKWRVIIGSKIHRRGLAITYTSKDF 226 + S M D +RDP W D + S +RG ++SKD Sbjct: 156 DELTSATKQGMIIDCPTDKVDHHYRDPKV-WKTGDTWYMTFGVSSADKRGQMWLFSSKDM 214 Query: 227 LKWE------KSPEPLHYDDGSGMWECPDFFPVTRFGSNGVETSSFGEPNEILKHVLKIS 280 ++WE + P+P + M ECPDF P+ N F + + Sbjct: 215 VRWEYERVLFQHPDPDVF-----MLECPDFSPIKDKDGNEKWVIGFSAMGSKPSGFMNRN 269 Query: 281 LDDTKHDYYTIGTYDRVKDKFVPDNGFKMDGTAPRYDYG-KYYASKTFFDSAKNRRILWG 339 + + Y IGT++ +F P+ F++ +D G YYA ++F + R+I++G Sbjct: 270 VSNAG---YMIGTWEP-GGEFKPETEFRL------WDCGHNYYAPQSF--NVDGRQIVYG 317 Query: 340 WTN---ESSSVEDDVEKGWSGIQTIPRKIWLDRSGKQLIQWPVREVERLRTKQVKNLRNK 396 W + + +EDD GW G T+PR+I L G ++ PV E+E LR + + Sbjct: 318 WMSPFVQPIPMEDD---GWCGQLTLPREITLGDDG-DVVTAPVAEMEGLREDTLDHGSVT 373 Query: 397 VLKSGSRLEVYGVTAAQADVEVLFKVRDLEKA 428 + G ++ A + ++ + E+A Sbjct: 374 LDMDGEQIIADDAEAVEIEMTIDLAASTAERA 405 >3SC7-X nrPDB Length = 516 Score = 105 bits (261), Expect = 6e-23, Method: Compositional matrix adjust. Identities = 142/558 (25%), Positives = 223/558 (39%), Gaps = 105/558 (18%) Query: 51 YRTGFHFQPPKNWMNDPNGPMIYKGIYHLFYQWNPKGAVWGNIVWAHSTSTDLINWDPHP 110 YR +HF P + WMN+PNG + +HLF+Q NP VWGNI W H+TSTDL++W P Sbjct: 28 YRPSYHFTPDQYWMNEPNGLIKIGSTWHLFFQHNPTANVWGNICWGHATSTDLMHWAHKP 87 Query: 111 PAIFPSAPFDING--CWSGSATILPN--------GKPVIL--YTGIDPKNQ-QVQNIAEP 157 AI D NG ++G+A PN P L +TG +Q Q Q +A Sbjct: 88 TAI-----ADENGVEAFTGTAYYDPNNTSGLGDSANPPYLAWFTGYTTSSQTQDQRLA-- 140 Query: 158 KNLSDPYLREWKKSPLNPLM-----APDAVNGINASSFRDPTTAWLGQDKKWRVIIGSKI 212 S W K NP++ AP + G S RDP + Q W +++ Sbjct: 141 --FSVDNGATWTKFQGNPIISTSQEAPHDITGGLES--RDPKVFFHRQSGNWIMVLAHGG 196 Query: 213 HRRGLAITYTSKDFLKWE-----KSPEPLHYDDGSGMWECPDFFPVTRFGSNGVETSSFG 267 + L+ +TS D + W KS WE PD F + G+ Sbjct: 197 QDK-LSF-WTSADTINWTWQSDLKSTSINGLSSDITGWEVPDMFELPVEGTEETTWVVMM 254 Query: 268 EPNEIL----KHVLKISLDDTKHDYYTIGTYDRVKDKFVPDNGFKMDGTAPRYDYGKYY- 322 P E VL I+ G++D F D +D + D G+ + Sbjct: 255 TPAEGSPAGGNGVLAIT-----------GSFD--GKSFTAD---PVDASTMWLDNGRDFD 298 Query: 323 --ASKTFFDSAKNRRILWGWTNESSSVEDDVEKGWSGIQTIPRKIWLDRSGKQ--LIQWP 378 S ++ RRI+ N S + W G+ + PR + L + G Q +Q P Sbjct: 299 GALSWVNVPASDGRRIIAAVMNSYGS--NPPTTTWKGMLSFPRTLSLKKVGTQQHFVQQP 356 Query: 379 VREVERLRTKQVKNLRNKVLKSGSRLEVYGVTAAQADVEVLFKVRDLEKADVIEPSWTDP 438 + E++ + T ++ L N+ + G L + + DV V F Sbjct: 357 ITELDTISTS-LQILANQTITPGQTL-LSSIRGTALDVRVAFYPD--------------- 399 Query: 439 QLICSKMNVSVKSGLGPFGLMVLASKNLEEYTSVYFRIFKARQNSNKYVVLMCSDQSRSS 498 S ++++V+ G + + + +YT + R S + ++ Sbjct: 400 --AGSVLSLAVRKG--------ASEQTVIKYTQSDATLSVDRTESGDISYDPAAGGVHTA 449 Query: 499 -LKEDNDKTTYGAFVDINPHQPLSLRALIDHSVVESFGGKGRACITSRVYPK-LAIGKSS 556 L+ED +S+R L+D VE FGG+G A I+ ++P + G + Sbjct: 450 KLEEDGTGL-------------VSIRVLVDTCSVEVFGGQGEAVISDLIFPSDSSDGLAL 496 Query: 557 HLFAFNYGYQSVDVLNLN 574 + N QSVDV +++ Sbjct: 497 EVTGGNAVLQSVDVRSVS 514 >3U14-A nrPDB Length = 535 Score = 91.3 bits (225), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 122/440 (27%), Positives = 185/440 (42%), Gaps = 89/440 (20%) Query: 52 RTGFHFQPPKNWMNDPNGPMIYKG--IYHLFYQWNPKGAVWGN-IVWAHSTSTDLINWDP 108 R HF P K WMN PNG K ++HL++Q+NP WG + W H+TS DL++WD Sbjct: 36 RPLIHFTPEKGWMNAPNGLFYDKTAKLWHLYFQYNPNATAWGQPLYWGHATSNDLVHWDE 95 Query: 109 HPPAIFPSAPFDINGCWSGS-------------ATILPNGKPVILYTGIDPKNQQVQNIA 155 H AI P D G +SGS ++I PN + V +YT P N Q Q+IA Sbjct: 96 HEIAIGPEH--DNEGIFSGSIVVDHNNTSGFFNSSIDPNQRIVAIYTNNIPDN-QTQDIA 152 Query: 156 EPKNLSDPYLREWKKSPLNPLMAPDAVNGINASSFRDPTTAWLGQDKKWRVIIGSKIHRR 215 +L Y + K NP++ ++++ FRDP W +W +++ SK Sbjct: 153 --FSLDGGY--TFTKYENNPVI------DVSSNQFRDPKVFWHEDSNQW-IMVVSKSQEY 201 Query: 216 GLAITYTSKDFLKWEKSPEPLHYDDGSG----MWECPDFFPVTRFGSNGVETSSF----- 266 + I + S + W L+ + SG +ECP V S+ + F Sbjct: 202 KIQI-FGSANLKNW-----VLNSNFSSGYYGNQYECPGLIEVPIENSDKSKWVMFLAINP 255 Query: 267 GEPNEILKHVLKISLDDTKHDYYTIGTYDRVKDKFVPDNGFKMDGTAPRYDYGK-YYASK 325 G P L S++ Y +G +D +FVPD D D GK +YA + Sbjct: 256 GSP-------LGGSINQ-----YFVGDFDGF--QFVPD-----DSQTRFVDIGKDFYAFQ 296 Query: 326 TFFDSAKNRRILWGWTNESSSVEDDVEKGWSGIQTIPRKIWL-----DRSGKQ--LIQWP 378 T F ++ + W + + W ++ R L + KQ LIQ P Sbjct: 297 T-FSEVEHGVLGLAWASNWQYADQVPTNPWRSSTSLARNYTLRYVHTNAETKQLTLIQNP 355 Query: 379 V-----REVERLRTKQVKNLRNKVLKSGSRLEVYGVTAAQADVEVLFKVRDLEKADVIEP 433 V V++L+ K VK K +K+ + + D + FKV +L + P Sbjct: 356 VLPDSINVVDKLKKKNVKLTNKKPIKTN-----FKGSTGLFDFNITFKVLNLN----VSP 406 Query: 434 SWT--DPQLICSKMNVSVKS 451 T D + ++N SV S Sbjct: 407 GKTHFDILINSQELNSSVDS 426 >4EQV-A nrPDB Length = 512 Score = 89.7 bits (221), Expect = 3e-18, Method: Compositional matrix adjust. Identities = 83/296 (28%), Positives = 132/296 (44%), Gaps = 53/296 (17%) Query: 56 HFQPPKNWMNDPNGPMIYK---GIYHLFYQWNPKGAVWGN-IVWAHSTSTDLINWDPHPP 111 HF P K WMNDPNG + Y +HL++Q+NP VWG + W H+TS DL NW+ P Sbjct: 12 HFTPNKGWMNDPNG-LWYDEKDAKWHLYFQYNPNDTVWGTPLFWGHATSDDLTNWEDQPI 70 Query: 112 AIFPSAPFDINGCWSGSATILPNGKPVILYTGIDPKNQQVQ----NIAEPKNLSDPY--- 164 AI P + +G +SGS + N IDP+ + V N E + Y Sbjct: 71 AIAPKR--NDSGAFSGSMVVDYNNTSGFFNDTIDPRQRCVAIWTYNTPESEEQYISYSLD 128 Query: 165 ----LREWKKSPLNPLMAPDAVNGINASSFRDPTTAWLGQDKKWRVIIGSKIHRRGLAIT 220 E++K NP++A N++ FRDP W +KW ++ +K + I Sbjct: 129 GGYTFTEYQK---NPVLA------ANSTQFRDPKVFWYEPSQKW-IMTAAKSQDYKIEI- 177 Query: 221 YTSKDFLKWEKSPEPLHYDDGSGMWECPDFFPVTRFGSNGVETSSFGEPNEILKHVLKIS 280 Y+S D W+ + +ECP +E + +P++ V+ IS Sbjct: 178 YSSDDLKSWKLESAFANEGFLGYQYECPGL----------IEVPTEQDPSKSY-WVMFIS 226 Query: 281 LD-----DTKHDYYTIGTYDRVKDKFVPDNGFKMDGTAPRYDYGK-YYASKTFFDS 330 ++ + Y +G+++ + D + D+GK YYA +TFF++ Sbjct: 227 INPGAPAGGSFNQYFVGSFNGTHFE-------AFDNQSRVVDFGKDYYALQTFFNT 275 >5FMB-A nrPDB Length = 665 Score = 65.1 bits (157), Expect = 7e-11, Method: Compositional matrix adjust. Identities = 137/585 (23%), Positives = 216/585 (36%), Gaps = 110/585 (18%) Query: 51 YRTGFHFQPPKNWMNDPNGPMIYK---GIYHLFYQWNPKGAVWGNIVWAHSTSTDLINWD 107 +R F P+ WMN P G +Y+ G H YQ +PK WGNI + S+D +W Sbjct: 65 FRPKARFIAPEGWMNAPMG--LYQRADGSIHAGYQSHPKHIQWGNISQGAAYSSDFTSWT 122 Query: 108 PHPPA-----IFPSAPFDINGCWSGSATILP---NGKPVILYTGI----------DPKNQ 149 + I+PS +DI G + GS I+ +G P ILYT + + Sbjct: 123 DFNGSEGYKTIWPSQIYDIRGVFDGS--IIKEGIDGYPTILYTSTSFGPLGATLNEAEGT 180 Query: 150 QVQNIAEPKNLSDPYLREWKKSPLNPLMA--PDAVNGINASSFRDP-------------- 193 + Q++A + +++ + NP++ P+ N + FRDP Sbjct: 181 ETQSLAYTTDDGASWIKLGYGAGQNPVIYEWPE----TNLTGFRDPYVFQSPRLEALLAN 236 Query: 194 TTAWLGQDKKWRVIIGSKIHRRG----LAITYTSKDFLKWEKSPEPL---HYDDGSGMWE 246 TT+ I +H G L +T+ +F+KW PL Y + G W Sbjct: 237 TTSITNATGDHFATISGGVHGDGARLFLYRQHTTGEFIKWTY-LGPLVTTGYKESYGEWS 295 Query: 247 CPDFFPVTRFGSNGVETSSFGEPNEILKHVLKISLDDTKHDYYTIGTYD----------- 295 +G N ET+ N D T D+ T GT Sbjct: 296 G-------NYGIN-FETAGVTRLNPA-GAAWDNGSDTTAVDFVTFGTEQGRADHQNHWPL 346 Query: 296 -RVKDKFVPDNGF--KMDGTAPRYDYGKYYASKTFFDSAKNRRILWGWTNESSSVEDDV- 351 D V DNG + + D+G+ YA + F R++ GW E +D+V Sbjct: 347 WAAVDYEVRDNGSIEAVIAYSGVQDWGRSYAYAS-FPVEGYRQVSVGWIYED---DDNVI 402 Query: 352 ---EKGWSGIQTIPRKIW------LDRSGKQLIQ---WPVREVERLRTKQVKNLRNKVLK 399 + G+ G T+ R ++ + S L + W + + V L +V+ Sbjct: 403 LAKQFGYQGAFTLFRDLFVKVVENVSPSTPGLFEQASWSTKNSTDGMSVTVTTLGQRVVP 462 Query: 400 SGSRLEVYGVTAAQADVEVLFKVRDLEKADVIEPSWTDPQLICSKMNVSVKSGL---GPF 456 E + V L V E A P + P + S + GL Sbjct: 463 -----ETLAAYKGNSTVSTLAPVMLNESAAAYTPFSSQPTDRFYALTGSFEFGLNTTAKA 517 Query: 457 GLMVLASKNLEEYTSVYFRIFKARQNSNKYVVLMCSDQSRSSLKEDNDKTTYGAFVDINP 516 G VLAS+ EEYT ++F S V+ + S D + + + Sbjct: 518 GFRVLASE--EEYTDIWF-----DPASENLTVVRTASSLIKSFGNDTELAKVKLYEIVGA 570 Query: 517 H-QPLSLRALIDHSVVESFGGKGRACITSRVYPKLAIGKSSHLFA 560 + L+L +D SV+E + +++R YP LA + L A Sbjct: 571 ESKTLNLTVFVDGSVIEIYAND-EVALSTRAYPWLANSTGAGLLA 614 >4FFH-A nrPDB Length = 492 Score = 60.5 bits (145), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 87/346 (25%), Positives = 136/346 (39%), Gaps = 68/346 (19%) Query: 55 FHFQPPKNWMNDPNGPMIYKGIYHLFY----QWNPKGAVWGNIVWAHSTSTDLINWDPHP 110 +H PP W+ +P P+ G Y L+Y Q N G W H+++TD + + H Sbjct: 4 YHMTPPSGWLCNPQRPVTTHGAYQLYYLHSDQNNGPGG------WDHASTTDGVAFTHHG 57 Query: 111 PAIFPSAP-FDINGCWSGSATI-------LPNGKPVILYT----GIDPKNQQVQNIAEPK 158 + P P F + WSGSA + G V L T G+ +Q + Sbjct: 58 -TVMPLRPDFPV---WSGSAVVDTANTAGFGAGAVVALATQPTDGVRKYQEQYLYWSTDG 113 Query: 159 NLSDPYLREWKKSPLNPLMAPDAVNGINASSFRDPTTAWLGQDKKWRVIIGSKIHRRGLA 218 + L + + A NA FRDP W +W +IG R A Sbjct: 114 GFTFTALPDPVIVNTDGRAATTPAEIENAEWFRDPKIHWDTARGEWVCVIG----RLRYA 169 Query: 219 ITYTSKDFLKWEKSPEPLHYDDGSGMWECPDFFPVTRFGSNGVETSSFGEPNEILKH-VL 277 YTS + W + + G ECPD F +T ++ +H VL Sbjct: 170 AFYTSPNLRDWTLRRNFDYPNHALGGIECPDLFEITA--------------DDGTRHWVL 215 Query: 278 KISLDD------TKHDYYTIGTYDRVKDKFVPDNGFKMDGTAPRY-DYG-KYYASKTF-- 327 S+D + Y+T GT+D + F D P++ D+G +YA+ T+ Sbjct: 216 AASMDAYGIGLPMTYAYWT-GTWDGEQ--------FHADDLTPQWLDWGWDWYAAVTWPS 266 Query: 328 FDSAKNRRILWGWTN----ESSSVEDDVEKGWSGIQTIPRKIWLDR 369 D+ + +R+ W N + V D G++G +I R++ L R Sbjct: 267 IDAPETKRLAIAWMNNWKYAARDVPTDASDGYNGQNSIVRELRLAR 312 >4IED-A nrPDB Length = 254 Score = 31.2 bits (69), Expect = 1.3, Method: Compositional matrix adjust. Identities = 25/86 (29%), Positives = 36/86 (41%), Gaps = 23/86 (26%) Query: 265 SFGEPNEILKHVLK----------ISLDDTKHDYYTIGTYDRVKDKFVPDNGFKM----- 309 SFG N+ +K + + L + K DYY + DR ++F P + FK+ Sbjct: 10 SFGNENQFMKEIFERKGLNGTFVVYDLKNDKIDYYNL---DRANERFYPASSFKIFNTLI 66 Query: 310 ---DGTAPRYDYGKYY--ASKTFFDS 330 +G D YY SK F DS Sbjct: 67 GLENGIVKNVDEMFYYYDGSKVFLDS 92 >2Z1Q-A nrPDB Length = 577 Score = 30.0 bits (66), Expect = 2.9, Method: Compositional matrix adjust. Identities = 35/129 (27%), Positives = 58/129 (44%), Gaps = 11/129 (8%) Query: 301 FVPDNGFKMDGTAPRYDYGKYYASKTFFDSAKNRRILWGWTNESSSVEDD---VEKGWSG 357 +V D G ++ G Y Y + Y + + A+ RI G TNE + + + + G Sbjct: 364 YVVDEGVQIHGG---YGYSQEYPIERAYRDARINRIFEG-TNEINRLLIPGMLLRRALKG 419 Query: 358 IQTIPRKIWLDRSGKQLIQWPVREVERLRTKQVKNLRNKVLK-SGSRLEVYGVTAAQADV 416 +P R K+L++ E E L QV+NL+ L +G ++ YG + + Sbjct: 420 --QLPLMQAAQRLQKELLEPSFEEPEDLELHQVQNLKKLALMVAGLAVQKYG-QGVEEEQ 476 Query: 417 EVLFKVRDL 425 EVL V D+ Sbjct: 477 EVLGAVADI 485 >2IO3-A nrPDB Length = 232 Score = 29.3 bits (64), Expect = 5.1, Method: Compositional matrix adjust. Identities = 15/54 (27%), Positives = 26/54 (48%) Query: 149 QQVQNIAEPKNLSDPYLREWKKSPLNPLMAPDAVNGINASSFRDPTTAWLGQDK 202 Q +Q+ ++ K SD L EW + P P +NG ++ F ++ +DK Sbjct: 153 QYLQDESKTKRNSDLNLLEWTHHSMKPHEIPQQLNGSDSGMFTCKYADYISRDK 206 >2XI1-A nrPDB Length = 208 Score = 28.9 bits (63), Expect = 6.0, Method: Compositional matrix adjust. Identities = 22/77 (28%), Positives = 33/77 (42%), Gaps = 6/77 (7%) Query: 39 STNTKSPSVNQPYRTGFHFQPPKNWMNDPNGPMIYKGIYHLFYQWNPKGAVWGNIVWAHS 98 S+NT + + ++ GF +P P PM YKG L + KG + G +V++ Sbjct: 54 SSNTDTTNADEEEEVGFPVRP-----QVPLRPMTYKGAVDLSFFLKEKGGLEG-LVYSQR 107 Query: 99 TSTDLINWDPHPPAIFP 115 L W H FP Sbjct: 108 EKEILDLWVYHTQGYFP 124 >6CA8-A nrPDB Length = 751 Score = 28.9 bits (63), Expect = 7.0, Method: Compositional matrix adjust. Identities = 24/106 (22%), Positives = 51/106 (48%), Gaps = 14/106 (13%) Query: 267 GEPNEILKHVLKISLDDTKHDYYTIGTYDRVKDKFVPDNGFKMD-----GTAPRYDYGKY 321 G +E + ++K+ ++ ++TI Y++ K+ G+K+ GT+ ++ Sbjct: 138 GFLSEFVTPIVKVQKGSQEYSFFTIAEYEQWKEN-TNLLGWKIKYYKGLGTSTDREF--- 193 Query: 322 YASKTFFDSAKNRRILWGWTNESSSVEDDVEKGWSGIQTIPRKIWL 367 K +F KN +I++ WT + D ++ +S + RK+WL Sbjct: 194 ---KQYFSDIKNHKIMFLWTGDRDG--DSIDMAFSKKRIEDRKLWL 234 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 2AC1-A nrPDB 754 0.0 2ADD-A nrPDB 651 0.0 3UGH-A nrPDB 600 e-172 1Y4W-A nrPDB 417 e-117 3SC7-X nrPDB 384 e-107 3PIG-A nrPDB 380 e-105 5FMB-A nrPDB 357 1e-98 1UYP-A nrPDB 333 2e-91 3U14-A nrPDB 321 4e-88 4EQV-A nrPDB 285 4e-77 4FFH-A nrPDB 258 6e-69 Sequences not found previously or not previously below threshold: 5XH8-A nrPDB 115 4e-26 3LFI-A nrPDB 97 2e-20 3R4Z-A nrPDB 40 0.005 5A7V-A nrPDB 38 0.014 3P2N-A nrPDB 38 0.015 2YFT-A nrPDB 37 0.027 3LV4-A nrPDB 36 0.040 4AK7-A nrPDB 35 0.12 2UYT-A nrPDB 34 0.15 3QEF-A nrPDB 34 0.17 3GHG-A nrPDB 34 0.23 3ZXJ-A nrPDB 33 0.27 4B2O-A nrPDB 33 0.30 2WLX-A nrPDB 33 0.31 3C7F-A nrPDB 33 0.33 3IB3-A nrPDB 33 0.41 6EUG-A nrPDB 33 0.44 6FRW-A nrPDB 33 0.45 4D47-A nrPDB 33 0.50 5TA9-A nrPDB 32 0.62 3R67-A nrPDB 32 0.64 5A8D-A nrPDB 32 0.75 4NOV-A nrPDB 32 0.82 4KCA-A nrPDB 32 0.89 5HX2-G nrPDB 31 1.4 3OM6-A nrPDB 31 1.8 3KST-A nrPDB 31 1.8 3BYN-A nrPDB 30 2.2 6A8I-A nrPDB 30 2.6 5JOY-A nrPDB 30 2.8 3MUN-A nrPDB 30 2.9 4KC7-A nrPDB 30 3.1 4YHG-A nrPDB 29 5.4 3WPZ-A nrPDB 29 5.6 4N4B-A nrPDB 28 10.0 >2AC1-A nrPDB Length = 541 Score = 754 bits (1946), Expect = 0.0, Method: Composition-based stats. Identities = 541/541 (100%), Positives = 541/541 (100%) Query: 44 SPSVNQPYRTGFHFQPPKNWMNDPNGPMIYKGIYHLFYQWNPKGAVWGNIVWAHSTSTDL 103 SPSVNQPYRTGFHFQPPKNWMNDPNGPMIYKGIYHLFYQWNPKGAVWGNIVWAHSTSTDL Sbjct: 1 SPSVNQPYRTGFHFQPPKNWMNDPNGPMIYKGIYHLFYQWNPKGAVWGNIVWAHSTSTDL 60 Query: 104 INWDPHPPAIFPSAPFDINGCWSGSATILPNGKPVILYTGIDPKNQQVQNIAEPKNLSDP 163 INWDPHPPAIFPSAPFDINGCWSGSATILPNGKPVILYTGIDPKNQQVQNIAEPKNLSDP Sbjct: 61 INWDPHPPAIFPSAPFDINGCWSGSATILPNGKPVILYTGIDPKNQQVQNIAEPKNLSDP 120 Query: 164 YLREWKKSPLNPLMAPDAVNGINASSFRDPTTAWLGQDKKWRVIIGSKIHRRGLAITYTS 223 YLREWKKSPLNPLMAPDAVNGINASSFRDPTTAWLGQDKKWRVIIGSKIHRRGLAITYTS Sbjct: 121 YLREWKKSPLNPLMAPDAVNGINASSFRDPTTAWLGQDKKWRVIIGSKIHRRGLAITYTS 180 Query: 224 KDFLKWEKSPEPLHYDDGSGMWECPDFFPVTRFGSNGVETSSFGEPNEILKHVLKISLDD 283 KDFLKWEKSPEPLHYDDGSGMWECPDFFPVTRFGSNGVETSSFGEPNEILKHVLKISLDD Sbjct: 181 KDFLKWEKSPEPLHYDDGSGMWECPDFFPVTRFGSNGVETSSFGEPNEILKHVLKISLDD 240 Query: 284 TKHDYYTIGTYDRVKDKFVPDNGFKMDGTAPRYDYGKYYASKTFFDSAKNRRILWGWTNE 343 TKHDYYTIGTYDRVKDKFVPDNGFKMDGTAPRYDYGKYYASKTFFDSAKNRRILWGWTNE Sbjct: 241 TKHDYYTIGTYDRVKDKFVPDNGFKMDGTAPRYDYGKYYASKTFFDSAKNRRILWGWTNE 300 Query: 344 SSSVEDDVEKGWSGIQTIPRKIWLDRSGKQLIQWPVREVERLRTKQVKNLRNKVLKSGSR 403 SSSVEDDVEKGWSGIQTIPRKIWLDRSGKQLIQWPVREVERLRTKQVKNLRNKVLKSGSR Sbjct: 301 SSSVEDDVEKGWSGIQTIPRKIWLDRSGKQLIQWPVREVERLRTKQVKNLRNKVLKSGSR 360 Query: 404 LEVYGVTAAQADVEVLFKVRDLEKADVIEPSWTDPQLICSKMNVSVKSGLGPFGLMVLAS 463 LEVYGVTAAQADVEVLFKVRDLEKADVIEPSWTDPQLICSKMNVSVKSGLGPFGLMVLAS Sbjct: 361 LEVYGVTAAQADVEVLFKVRDLEKADVIEPSWTDPQLICSKMNVSVKSGLGPFGLMVLAS 420 Query: 464 KNLEEYTSVYFRIFKARQNSNKYVVLMCSDQSRSSLKEDNDKTTYGAFVDINPHQPLSLR 523 KNLEEYTSVYFRIFKARQNSNKYVVLMCSDQSRSSLKEDNDKTTYGAFVDINPHQPLSLR Sbjct: 421 KNLEEYTSVYFRIFKARQNSNKYVVLMCSDQSRSSLKEDNDKTTYGAFVDINPHQPLSLR 480 Query: 524 ALIDHSVVESFGGKGRACITSRVYPKLAIGKSSHLFAFNYGYQSVDVLNLNAWSMNSAQI 583 ALIDHSVVESFGGKGRACITSRVYPKLAIGKSSHLFAFNYGYQSVDVLNLNAWSMNSAQI Sbjct: 481 ALIDHSVVESFGGKGRACITSRVYPKLAIGKSSHLFAFNYGYQSVDVLNLNAWSMNSAQI 540 Query: 584 S 584 S Sbjct: 541 S 541 >2ADD-A nrPDB Length = 543 Score = 651 bits (1678), Expect = 0.0, Method: Composition-based stats. Identities = 281/541 (51%), Positives = 389/541 (71%), Gaps = 14/541 (2%) Query: 47 VNQPYRTGFHFQPPKNWMNDPNGPMIYKGIYHLFYQWNPKGAVWGN-IVWAHSTSTDLIN 105 + QPYRTG+HFQPP NWMNDPNGPM+Y+G+YH FYQ+NP A +G+ I+W H+ S DL+N Sbjct: 3 IEQPYRTGYHFQPPSNWMNDPNGPMLYQGVYHFFYQYNPYAATFGDVIIWGHAVSYDLVN 62 Query: 106 WDPHPPAIFPSAPFDINGCWSGSATILPNGKPVILYTGIDPKNQQVQNIAEPKNLSDPYL 165 W PAI+P+ D CWSGSATILP P +LYTG D K++QVQ++A PKNLSDP+L Sbjct: 63 WIHLDPAIYPTQEADSKSCWSGSATILPGNIPAMLYTGSDSKSRQVQDLAWPKNLSDPFL 122 Query: 166 REWKKSPLNPLMAPDAVNGINASSFRDPTTAWLGQDKKWRVIIGSKIHRRGLAITYTSKD 225 REW K P NPL+ P G+ FRDP+TAWLG D WR+++G G+A Y S D Sbjct: 123 REWVKHPKNPLITP--PEGVKDDCFRDPSTAWLGPDGVWRIVVGGDRDNNGMAFLYQSTD 180 Query: 226 FLKWEKSPEPLHYDDGSGMWECPDFFPVTRFGSNGVETSSFGEPNEILKHVLKISLDDTK 285 F+ W++ +PL D +G WECPDF+PV +NG++TS +G ++HV+K + Sbjct: 181 FVNWKRYDQPLSSADATGTWECPDFYPVPLNSTNGLDTSVYGG---SVRHVMKAGFE--G 235 Query: 286 HDYYTIGTYDRVKDKFVPDNGFKMDGTA--PRYDYGKYYASKTFFDSAKNRRILWGWTNE 343 HD+YTIGTY ++ F+P NG + G+ RYDYG++YASK+FFD AKNRR+LW W E Sbjct: 236 HDWYTIGTYSPDRENFLPQNGLSLTGSTLDLRYDYGQFYASKSFFDDAKNRRVLWAWVPE 295 Query: 344 SSSVEDDVEKGWSGIQTIPRKIWLDRSGKQLIQWPVREVERLRTKQVKNLRNKVLKSGSR 403 + S DD+EKGW+G+Q+ PR +W+DR+GKQLIQWPV E+E LR QV NL+NK LK GS Sbjct: 296 TDSQADDIEKGWAGLQSFPRALWIDRNGKQLIQWPVEEIEELRQNQV-NLQNKNLKPGSV 354 Query: 404 LEVYGVTAAQADVEVLFKVRDLEKADVIEPSWTDPQLICSKMNVSVKSGLGPFGLMVLAS 463 LE++G+ A+QADV + FK+ L++A+V++ + DPQ +C++ S + LGPFGL+ +AS Sbjct: 355 LEIHGIAASQADVTISFKLEGLKEAEVLDTTLVDPQALCNERGASSRGALGPFGLLAMAS 414 Query: 464 KNLEEYTSVYFRIFKARQNSNKYVVLMCSDQSRSSLKEDNDKTTYGAFVDINPH-QPLSL 522 K+L+E ++++FR+F+ + +Y VLMCSD SRS+++ + D T+YGAFVDI+P + +SL Sbjct: 415 KDLKEQSAIFFRVFQNQL--GRYSVLMCSDLSRSTVRSNIDTTSYGAFVDIDPRSEEISL 472 Query: 523 RALIDHSVVESFGGKGRACITSRVYPKLAIGKSSHLFAFNYGYQSVDVLNLNAWSMNSAQ 582 R LIDHS++ESFG G+ CITSR+YPK + +HLF FN G Q+V + ++AWSM +A+ Sbjct: 473 RNLIDHSIIESFGAGGKTCITSRIYPKFVNNEEAHLFVFNNGTQNVKISEMSAWSMKNAK 532 Query: 583 I 583 Sbjct: 533 F 533 >3UGH-A nrPDB Length = 546 Score = 600 bits (1545), Expect = e-172, Method: Composition-based stats. Identities = 231/534 (43%), Positives = 319/534 (59%), Gaps = 13/534 (2%) Query: 52 RTGFHFQPPKNWMNDPNGPMIYKGIYHLFYQWNPKGAVWGNIVWAHSTSTDLINWDPHPP 111 RT FHFQP ++WM+DP+GP+ YKG YH FYQ+NP VWGN W H+ S DLI+W P Sbjct: 19 RTAFHFQPERSWMSDPDGPIFYKGWYHFFYQYNPDNPVWGNNTWGHTVSRDLIHWLYLPL 78 Query: 112 AIFPSAPFDINGCWSGSATILPNGKPVILYTGIDPKNQQVQNIAEPKNLSDPYLREWKKS 171 A+ +D+ G +SGSAT LP+G+ ++LYTG+ + ++ ++A P +LSDP L EW K Sbjct: 79 ALAADQWYDMQGVFSGSATCLPDGRIMMLYTGVTKEMVEMLSLAYPADLSDPLLVEWVKY 138 Query: 172 PLNPLMAPDAVNGINASSFRDPTTAWLGQDKKWRVIIGSKIHRRGLAITYTSKDFLKWEK 231 P NP+++ A G++ + FRD +T W + WR+ IG+K + G+A+ Y +KDF ++ Sbjct: 139 PGNPILS--APPGVSPTEFRDASTGWYVSNGTWRIAIGAKYNTTGIAMVYETKDFKSFKL 196 Query: 232 SPEPLHYDDGSGMWECPDFFPVTRFGSNGVETSSFGEPNEILKHVLKISLDDTKHDYYTI 291 E LH +G+WEC D +PV+ G G+ETS G +KHVLK S+D+ + DYY I Sbjct: 197 LEELLHAVPDTGLWECVDLYPVSTTGEKGLETSVNGP---KVKHVLKASIDEQQRDYYAI 253 Query: 292 GTYDRVKDKFVPDNGFKMDGTAPRYDYGKYYASKTFFDSAKNRRILWGWTNESSSVEDDV 351 GTYD +K+ PDN + G RYD+GKYYASKTF+D K RR++W WT E S D Sbjct: 254 GTYDLGTNKWTPDNPEEDVGIGLRYDWGKYYASKTFYDPKKQRRVVWAWTKELDSEVADR 313 Query: 352 EKGWSGIQTIPRKIWLD-RSGKQLIQWPVREVERLRTKQVKNLRNKVLKSGSRLEVYGVT 410 EKGW+ +QTIPR + LD ++G ++ WPV EVE LR K +GS + + T Sbjct: 314 EKGWANVQTIPRTVLLDQKTGTNVLLWPVEEVESLRLSS-KEFSKVKAGAGSVVPLDVGT 372 Query: 411 AAQADVEVLFKVRDLEKADVIEPSWTDPQLICSKMNVSVKSG-LGPFGLMVLASKNLEEY 469 A Q D+ F++ IE D C+ + + G LGPFGL+V A++NL E Sbjct: 373 ATQLDIIAEFEIDKEALEGTIE---ADMGYNCTTSGGAAERGVLGPFGLLVSATENLSEQ 429 Query: 470 TSVYFRIFKARQNSNKYVVLMCSDQSRSSLKEDNDKTTYGAFVDINPHQPLSLRALIDHS 529 T VYF I A+ + C D+SRSS D K G V + + ++R L+DHS Sbjct: 430 TPVYFYI--AKGTDGNFKTFFCLDESRSSKASDVSKQVKGFTVPVLDGEKFTMRLLVDHS 487 Query: 530 VVESFGGKGRACITSRVYPKLAIGKSSHLFAFNYGYQSVDVLNLNAWSMNSAQI 583 +VESF GR+CITSRVYP AI ++ LF FN + +L W MNSA I Sbjct: 488 IVESFAQGGRSCITSRVYPTEAIYGAAKLFLFNNATGASITASLKIWEMNSAFI 541 >1Y4W-A nrPDB Length = 518 Score = 417 bits (1072), Expect = e-117, Method: Composition-based stats. Identities = 129/529 (24%), Positives = 208/529 (39%), Gaps = 69/529 (13%) Query: 48 NQPYRTGFHFQPPKNWMNDPNGPMIYKGIYHLFYQWNPKGAVWGNIVWAHSTSTDLINWD 107 +QPYR +HF P KNWMNDPNG + + G YHLF+Q+NP G WGNI W H+ S DL +W+ Sbjct: 4 DQPYRGQYHFSPQKNWMNDPNGLLYHNGTYHLFFQYNPGGIEWGNISWGHAISEDLTHWE 63 Query: 108 PHPPAIFPSA-PFDINGC-WSGSATILPNGK----------PVILYTGI------DPKNQ 149 P A+ D+ +SGSA N V +YT P Q Sbjct: 64 EKPVALLARGFGSDVTEMYFSGSAVADVNNTSGFGKDGKTPLVAMYTSYYPVAQTLPSGQ 123 Query: 150 QVQNIAEPKNLS---DPYLREWKKSPLNPLMA-PDAVNGINASSFRDPTTAWLGQDKKWR 205 VQ + ++++ D L NP++ P + +FRDP W + +KW Sbjct: 124 TVQEDQQSQSIAYSLDDGLTWTTYDAANPVIPNPPSPYEAEYQNFRDPFVFWHDESQKWV 183 Query: 206 VIIG-SKIHRRGLAITYTSKDFLKWEKSPEPLHYDDGSGMWECPDFFPVTRFGSNGVETS 264 V+ +++H+ + YTS + W+ E Y+ G+WECP + N + Sbjct: 184 VVTSIAELHKLAI---YTSDNLKDWKLVSEFGPYNAQGGVWECPGLVKLPLDSGNSTKWV 240 Query: 265 SFGEPNEILKHVLKISLDDTKHDYYTIGTYDRVKDKFVPDNGFKMDGTAPRYDYG-KYYA 323 N Y +G +D D + + TA D+G +YA Sbjct: 241 ITSGLNPGGP-----PGTVGSGTQYFVGEFDGTTFTPDADTVYPGNSTANWMDWGPDFYA 295 Query: 324 SKTFFDSAKNRRILWGWTNESSSVEDDVEKGWSGIQTIPRKIWLDRSGKQ--LIQWPVRE 381 + + + N + GW N + W IPR + L G + L+Q P Sbjct: 296 AAGYNGLSLNDHVHIGWMNNWQYGANIPTYPWRSAMAIPRHMALKTIGSKATLVQQPQEA 355 Query: 382 VERLRTKQVKNLRNKVLKSGSRLEVYGVTAAQADVEVLFKVRDLEKADVIEPSWTDPQLI 441 + K + + ++ K+ + + FKV Sbjct: 356 WSSISNK--RPIYSRTFKT-----LSEGSTNTTTTGETFKVD------------------ 390 Query: 442 CSKMNVSVKSGLGPFGLMVLASKNLEEYTSVYFRIFKARQNSNKYVVLMCSDQSRSSLKE 501 ++ S KS F + + AS N E T V + K + + + S + Sbjct: 391 ---LSFSAKSKASTFAIALRASANFTEQTLVGYDFAKQQ-------IFLDRTHSGDVSFD 440 Query: 502 DNDKTTYGAFVDINPHQPLSLRALIDHSVVESFGGKGRACITSRVYPKL 550 + + Y + + + L +D S VE FGG+G +T++++P Sbjct: 441 ETFASVYHGPLTPDSTGVVKLSIFVDRSSVEVFGGQGETTLTAQIFPSS 489 >3SC7-X nrPDB Length = 516 Score = 384 bits (985), Expect = e-107, Method: Composition-based stats. Identities = 133/551 (24%), Positives = 214/551 (38%), Gaps = 91/551 (16%) Query: 51 YRTGFHFQPPKNWMNDPNGPMIYKGIYHLFYQWNPKGAVWGNIVWAHSTSTDLINWDPHP 110 YR +HF P + WMN+PNG + +HLF+Q NP VWGNI W H+TSTDL++W P Sbjct: 28 YRPSYHFTPDQYWMNEPNGLIKIGSTWHLFFQHNPTANVWGNICWGHATSTDLMHWAHKP 87 Query: 111 PAIFPSAPFDINGCWSGSATILPNG--------KPVIL--YTGIDPKNQ-QVQNIAEPKN 159 AI + ++G+A PN P L +TG +Q Q Q +A Sbjct: 88 TAIADENGVE---AFTGTAYYDPNNTSGLGDSANPPYLAWFTGYTTSSQTQDQRLA---- 140 Query: 160 LSDPYLREWKKSPLNPLM-----APDAVNGINASSFRDPTTAWLGQDKKWRVIIGSKIHR 214 S W K NP++ AP + G S RDP + Q W +++ Sbjct: 141 FSVDNGATWTKFQGNPIISTSQEAPHDITGGLES--RDPKVFFHRQSGNWIMVLAHGGQD 198 Query: 215 RGLAITYTSKDFLKWE-----KSPEPLHYDDGSGMWECPDFFPVTRFGSNGVETSSFGEP 269 + +TS D + W KS WE PD F + G+ P Sbjct: 199 K--LSFWTSADTINWTWQSDLKSTSINGLSSDITGWEVPDMFELPVEGTEETTWVVMMTP 256 Query: 270 NEILKHVLKISLDDTKHDYYTIGTYDRVKDKFVPDNGFKMDGTAPRYDYGKYY---ASKT 326 E S G++D P +D + D G+ + S Sbjct: 257 AEG-------SPAGGNGVLAITGSFDGKSFTADP-----VDASTMWLDNGRDFDGALSWV 304 Query: 327 FFDSAKNRRILWGWTNESSSVEDDVEKGWSGIQTIPRKIWLDRSGKQ--LIQWPVREVER 384 ++ RRI+ N S + W G+ + PR + L + G Q +Q P+ E++ Sbjct: 305 NVPASDGRRIIAAVMNSYGS--NPPTTTWKGMLSFPRTLSLKKVGTQQHFVQQPITELDT 362 Query: 385 LRTKQVKNLRNKVLKSGSRLEVYGVTAAQADVEVLFKVRDLEKADVIEPSWTDPQLICSK 444 + T ++ L N+ + G L + + DV V F S Sbjct: 363 ISTS-LQILANQTITPGQTL-LSSIRGTALDVRVAFYPD-----------------AGSV 403 Query: 445 MNVSVKSGLGPFGLMVLASKNLEEYTSVYFRIFKARQNSNKYVVLMCSDQSRSSLKEDND 504 ++++V+ G + + + +YT + R S + ++ E+ Sbjct: 404 LSLAVRKG--------ASEQTVIKYTQSDATLSVDRTESGDISYDPAAGGVHTAKLEE-- 453 Query: 505 KTTYGAFVDINPHQPLSLRALIDHSVVESFGGKGRACITSRVYPK-LAIGKSSHLFAFNY 563 + +S+R L+D VE FGG+G A I+ ++P + G + + N Sbjct: 454 ----------DGTGLVSIRVLVDTCSVEVFGGQGEAVISDLIFPSDSSDGLALEVTGGNA 503 Query: 564 GYQSVDVLNLN 574 QSVDV +++ Sbjct: 504 VLQSVDVRSVS 514 >3PIG-A nrPDB Length = 526 Score = 380 bits (974), Expect = e-105, Method: Composition-based stats. Identities = 133/543 (24%), Positives = 208/543 (38%), Gaps = 74/543 (13%) Query: 48 NQPYRTGFHFQPPKNWMNDPNGPMIYKGIYHLFYQWNPKGAVWGNIVWAHSTSTDLINWD 107 N + +H W+NDPNG YKG +H+FYQ +P G WG + W H +STD++NW Sbjct: 36 NNRWYPKYHIASNGGWINDPNGLCFYKGRWHVFYQLHPYGTQWGPMHWGHVSSTDMLNWK 95 Query: 108 PHPPAIFPSAPFDINGCWSGSATILPNGKPVILYTGIDPKNQ--------QVQNIAEPKN 159 P PS + +G +SGSA I NG YTG N QVQ A P N Sbjct: 96 REPIMFAPSLEQEKDGVFSGSAVIDDNGDLRFYYTGHRWANGHDNTGGDWQVQMTALPDN 155 Query: 160 LSDPYLREWKKSPLNPLMAPDAVNGINASSFRDPTTAWLGQDKKWRVIIGSKIHRRGLAI 219 + S M D +RDP W D + S +RG Sbjct: 156 -------DELTSATKQGMIIDCPTDKVDHHYRDPKV-WKTGDTWYMTFGVSSADKRGQMW 207 Query: 220 TYTSKDFLKWEKSPE-PLHYDDGSGMWECPDFFPVTRFGSNGVETSSFGEPNEILKHVLK 278 ++SKD ++WE H D M ECPDF P+ N F + Sbjct: 208 LFSSKDMVRWEYERVLFQHPDPDVFMLECPDFSPIKDKDGNEKWVIGFSAMGSKPSGFMN 267 Query: 279 ISLDDTKHDYYTIGTYDRVKDKFVPDNGFKMDGTAPRYDYG-KYYASKTFFDSAKNRRIL 337 ++ + Y IGT++ +F P+ F++ +D G YYA ++F + R+I+ Sbjct: 268 RNVSNAG---YMIGTWEPGG-EFKPETEFRL------WDCGHNYYAPQSF--NVDGRQIV 315 Query: 338 WGWTNESSSVEDDVEKGWSGIQTIPRKIWLDRSGKQLIQWPVREVERLRTKQVKNLRNKV 397 +GW + + GW G T+PR+I L G ++ PV E+E LR + + + Sbjct: 316 YGWMSPFVQPIPMEDDGWCGQLTLPREITLGDDG-DVVTAPVAEMEGLREDTLDHGSVTL 374 Query: 398 LKSGSRLEVYGVTAAQADVEVLFKVRDLEKADVIEPSWTDPQLICSKMNVSVKSGLGPFG 457 G ++ A + ++ + E+A G Sbjct: 375 DMDGEQIIADDAEAVEIEMTIDLAASTAERA----------------------------G 406 Query: 458 LMVLASKNLEEYTSVYFRIFKARQNSNKYVVLMCSDQSRSSLKEDNDKTTYGAFVDINPH 517 L + A+++ YT V + R ++ + R++ D + + Sbjct: 407 LKIHATEDGA-YTYVAYDGQIGRVVVDRQAMANGDRGYRAAPLTDAELAS---------- 455 Query: 518 QPLSLRALIDHSVVESFGGKGRACITSRVYPKLAIGKSSHLFAFNYGYQSVDVLNLNAWS 577 L LR +D VE + G ++S Y + S+ V +L Sbjct: 456 GKLDLRVFVDRGSVEVYVNGGHQVLSSYSYAS----EGPRAIKLVAESGSLKVDSLKLHH 511 Query: 578 MNS 580 M S Sbjct: 512 MKS 514 >5FMB-A nrPDB Length = 665 Score = 357 bits (915), Expect = 1e-98, Method: Composition-based stats. Identities = 135/594 (22%), Positives = 207/594 (34%), Gaps = 93/594 (15%) Query: 51 YRTGFHFQPPKNWMNDPNGPM-IYKGIYHLFYQWNPKGAVWGNIVWAHSTSTDLINWDPH 109 +R F P+ WMN P G G H YQ +PK WGNI + S+D +W Sbjct: 65 FRPKARFIAPEGWMNAPMGLYQRADGSIHAGYQSHPKHIQWGNISQGAAYSSDFTSWTDF 124 Query: 110 PPA-----IFPSAPFDINGCWSGSATILP-NGKPVILYTGI----------DPKNQQVQN 153 + I+PS +DI G + GS +G P ILYT + + + Q+ Sbjct: 125 NGSEGYKTIWPSQIYDIRGVFDGSIIKEGIDGYPTILYTSTSFGPLGATLNEAEGTETQS 184 Query: 154 IAEPKNLSDPYLREWKKSPLNPLMAPDAVNGINASSFRDPTTA--------------WLG 199 +A + +++ + NP++ N + FRDP Sbjct: 185 LAYTTDDGASWIKLGYGAGQNPVIYEWP--ETNLTGFRDPYVFQSPRLEALLANTTSITN 242 Query: 200 QDKKWRVIIGSKIHRRG----LAITYTSKDFLKWEKSPEPL---HYDDGSGMWECPDFFP 252 I +H G L +T+ +F+KW PL Y + G W Sbjct: 243 ATGDHFATISGGVHGDGARLFLYRQHTTGEFIKWT-YLGPLVTTGYKESYGEWSG----- 296 Query: 253 VTRFGSNGVETSSFGEPNEILKHVLKISLDDTKHDYYTIGTYDR------------VKDK 300 +G N ET+ N D T D+ T GT D Sbjct: 297 --NYGIN-FETAGVTRLNPA-GAAWDNGSDTTAVDFVTFGTEQGRADHQNHWPLWAAVDY 352 Query: 301 FVPDNGF--KMDGTAPRYDYGKYYASKTFFDSAKNRRILWGWTNESSS-VEDDVEKGWSG 357 V DNG + + D+G+ YA +F R++ GW E V + G+ G Sbjct: 353 EVRDNGSIEAVIAYSGVQDWGRSYAYASF-PVEGYRQVSVGWIYEDDDNVILAKQFGYQG 411 Query: 358 IQTIPRKIWLD------RSGKQLIQ---WPVREVERLRTKQVKNLRNKVLKSGSRLEVYG 408 T+ R +++ S L + W + + V L +V+ E Sbjct: 412 AFTLFRDLFVKVVENVSPSTPGLFEQASWSTKNSTDGMSVTVTTLGQRVVP-----ETLA 466 Query: 409 VTAAQADVEVLFKVRDLEKADVIEPSWTDPQLICSKMNVSVKSGL---GPFGLMVLASKN 465 + V L V E A P + P + S + GL G VLAS+ Sbjct: 467 AYKGNSTVSTLAPVMLNESAAAYTPFSSQPTDRFYALTGSFEFGLNTTAKAGFRVLASE- 525 Query: 466 LEEYTSVYFRIFKARQNSNKYVVLMCSDQSRSSLKEDNDKTTYGAFVDINPH-QPLSLRA 524 EEYT ++F S V+ + S D + + + + L+L Sbjct: 526 -EEYTDIWF-----DPASENLTVVRTASSLIKSFGNDTELAKVKLYEIVGAESKTLNLTV 579 Query: 525 LIDHSVVESFGGKGRACITSRVYPKLAIGKSSHLFA-FNYGYQSVDVLNLNAWS 577 +D SV+E + +++R YP LA + L A V V L W Sbjct: 580 FVDGSVIEIYAND-EVALSTRAYPWLANSTGAGLLADGTTAGDVVGVSGLELWD 632 >1UYP-A nrPDB Length = 432 Score = 333 bits (852), Expect = 2e-91, Method: Composition-based stats. Identities = 106/406 (26%), Positives = 188/406 (46%), Gaps = 54/406 (13%) Query: 51 YRTGFHFQPPKNWMNDPNGPMIYKGIYHLFYQWNPKGAVWGNIVWAHSTSTDLINWDPHP 110 ++ +HF P WMNDPNG + +KG YH+FYQ+NP+ WGNI W H+ S DL++W P Sbjct: 2 FKPNYHFFPITGWMNDPNGLIFWKGKYHMFYQYNPRKPEWGNICWGHAVSDDLVHWRHLP 61 Query: 111 PAIFPSAPFDINGCWSGSATILPNGKPVILYTGI-DPKNQQVQNIAEPKNLSDPYLREWK 169 A++P + +G +SGSA + +GK ++YT DP + + + + +S+ L ++ Sbjct: 62 VALYPDD--ETHGVFSGSA-VEKDGKMFLVYTYYRDPTHNKGEKETQCVVMSENGL-DFV 117 Query: 170 KSPLNPLMAPDAVNGINASSFRDPTTAWLGQDKKWRVIIGS-KIHRRGLAITYTSKDFLK 228 K NP+++ G +A FRDP + +WR+++GS K + G + YTS D Sbjct: 118 KYDGNPVISKPPEEGTHA--FRDPKVN--RSNGEWRMVLGSGKDEKIGRVLLYTSDDLFH 173 Query: 229 WEKSPEPLHYDDGSGMWECPDFFPVTRFGSNGVETSSFGEPNEILKHVLKISLDDTKHDY 288 W+ + D+ + ECPD + K +L S+ T Sbjct: 174 WK-YEGAIFEDETTKEIECPDLVRI------------------GEKDILIYSITSTNSVL 214 Query: 289 YTIGTYDRVKDKFVPDNGFKMDGTAPRYDYGKYYASKTFFDSAKNRRILWGWTNES--SS 346 +++G K V G GT +YA++TFF + +R ++ GW + Sbjct: 215 FSMGELKEGKLN-VEKRGLLDHGT-------DFYAAQTFFGT--DRVVVIGWLQSWLRTG 264 Query: 347 VEDDVEKGWSGIQTIPRKIWLDRSGKQLIQWPVREVERLRTKQVKNLRNKVLKSGSRLEV 406 + +GW+G+ ++PR+++++ + +L PV E+ LR ++V S + Sbjct: 265 LYPTKREGWNGVMSLPRELYVENN--ELKVKPVDELLALRKRKVFETAK------SGTFL 316 Query: 407 YGVTAAQADVEVLFK-----VRDLEKADVIEPSWTDPQLICSKMNV 447 V ++ F E +V+ D ++ + + Sbjct: 317 LDVKENSYEIVCEFSGEIELRMGNESEEVVITKSRDELIVDTTRSG 362 >3U14-A nrPDB Length = 535 Score = 321 bits (823), Expect = 4e-88, Method: Composition-based stats. Identities = 125/525 (23%), Positives = 197/525 (37%), Gaps = 87/525 (16%) Query: 52 RTGFHFQPPKNWMNDPNGPMIYKGI--YHLFYQWNPKGAVWG-NIVWAHSTSTDLINWDP 108 R HF P K WMN PNG K +HL++Q+NP WG + W H+TS DL++WD Sbjct: 36 RPLIHFTPEKGWMNAPNGLFYDKTAKLWHLYFQYNPNATAWGQPLYWGHATSNDLVHWDE 95 Query: 109 HPPAIFPSAPFDINGCWSGS-------------ATILPNGKPVILYTGIDPKNQQVQNIA 155 H AI P D G +SGS ++I PN + V +YT P N Q Q+IA Sbjct: 96 HEIAIGPEH--DNEGIFSGSIVVDHNNTSGFFNSSIDPNQRIVAIYTNNIPDN-QTQDIA 152 Query: 156 EPKNLSDPYLREWKKSPLNPLMAPDAVNGINASSFRDPTTAWLGQDKKWRVIIGSKIHRR 215 S + K NP++ ++++ FRDP W +W +++ SK Sbjct: 153 ----FSLDGGYTFTKYENNPVI------DVSSNQFRDPKVFWHEDSNQWIMVV-SKSQEY 201 Query: 216 GLAITYTSKDFLKWEKSPEPLHYDDGSGMWECPDFFPVTRFGSNGVETSSFGEPNEILKH 275 + I + S + W + +ECP V S+ + F N Sbjct: 202 KIQI-FGSANLKNWVLNSNF-SSGYYGNQYECPGLIEVPIENSDKSKWVMFLAINPG--- 256 Query: 276 VLKISLDDTKHDYYTIGTYDRVKDKFVPDNGFKMDGTAPRYDYG-KYYASKTFFDSAKNR 334 S + Y +G +D +FVPD D D G +YA +TF ++ Sbjct: 257 ----SPLGGSINQYFVGDFDG--FQFVPD-----DSQTRFVDIGKDFYAFQTF-SEVEHG 304 Query: 335 RILWGWTNESSSVEDDVEKGWSGIQTIPRKIWL-----DRSGKQ--LIQWPV-----REV 382 + W + + W ++ R L + KQ LIQ PV V Sbjct: 305 VLGLAWASNWQYADQVPTNPWRSSTSLARNYTLRYVHTNAETKQLTLIQNPVLPDSINVV 364 Query: 383 ERLRTKQVKNLRNKVLKSGSRLEVYGVTAAQADVEVLFKVRDLEKADVIEPSWTDPQLIC 442 ++L+ K VK K +K+ + + D + FKV +L + D + Sbjct: 365 DKLKKKNVKLTNKKPIKTN-----FKGSTGLFDFNITFKVLNLNVSPGKTHF--DILINS 417 Query: 443 SKMNVSVKSGLGPFGLMVLASKNLEEYTSVYFRIFKARQNSNKYVVLMCSDQSRSSLKED 502 ++N SV S F + + F I + N R D Sbjct: 418 QELNSSVDSIKIGF-----------DSSQSSFYIDRHIPNVE---------FPRKQFFTD 457 Query: 503 NDKTTYGAFVDINPHQPLSLRALIDHSVVESFGGKGRACITSRVY 547 + SL ++D +++E + G +T+ + Sbjct: 458 KLAAYLEPLDYDQDLRVFSLYGIVDKNIIELYFNDGTVAMTNTFF 502 >4EQV-A nrPDB Length = 512 Score = 285 bits (728), Expect = 4e-77, Method: Composition-based stats. Identities = 110/526 (20%), Positives = 183/526 (34%), Gaps = 64/526 (12%) Query: 52 RTGFHFQPPKNWMNDPNGPMIY--KGIYHLFYQWNPKGAVWG-NIVWAHSTSTDLINWDP 108 R HF P K WMNDPNG +HL++Q+NP VWG + W H+TS DL NW+ Sbjct: 8 RPLVHFTPNKGWMNDPNGLWYDEKDAKWHLYFQYNPNDTVWGTPLFWGHATSDDLTNWED 67 Query: 109 HPPAIFPSAPFDINGCWSGSATILPNGKPVILYTGIDPKNQQVQNIAEPK--------NL 160 P AI P + +G +SGS + N IDP+ + V + Sbjct: 68 QPIAIAPKR--NDSGAFSGSMVVDYNNTSGFFNDTIDPRQRCVAIWTYNTPESEEQYISY 125 Query: 161 SDPYLREWKKSPLNPLMAPDAVNGINASSFRDPTTAWLGQDKKWRVIIGSKIHRRGLAIT 220 S + + NP++A N++ FRDP W +KW ++ +K + I Sbjct: 126 SLDGGYTFTEYQKNPVLA------ANSTQFRDPKVFWYEPSQKW-IMTAAKSQDYKIEI- 177 Query: 221 YTSKDFLKWEKSPEPLHYDDGSGMWECPDFFPVTRF-GSNGVETSSFGEPNEILKHVLKI 279 Y+S D W+ + +ECP V + F N Sbjct: 178 YSSDDLKSWKLESAFANEGFLGYQYECPGLIEVPTEQDPSKSYWVMFISINPGAPA---- 233 Query: 280 SLDDTKHDYYTIGTYDRVKDKFVPDNGFKMDGTAPRYDYG-KYYASKTFF--DSAKNRRI 336 + Y +G+++ + D + D+G YYA +TFF D + Sbjct: 234 ---GGSFNQYFVGSFNGTHFE-------AFDNQSRVVDFGKDYYALQTFFNTDPTYGSAL 283 Query: 337 LWGWTNESSSVEDDVEKGWSGIQTIPRKIWLDRSGKQLIQWPVREVERLRTKQVKNLRNK 396 W + W ++ RK L+ + P E+ L+ + + N+ N Sbjct: 284 GIAWASNWEYSAFVPTNPWRSSMSLVRKFSLN---TEYQANPETELINLKAEPILNISN- 339 Query: 397 VLKSGSRLEVYGVTAAQADVEVLFKVRDLEKADVIEPSWTDPQLICSKMNVSVKSGLGPF 456 SR T + V +E ++ SV Sbjct: 340 -AGPWSRF----ATNTTLTKANSYNVDLSNSTGTLEFELVYAVNTTQTISKSV---FADL 391 Query: 457 GLMVLASKNLEEYTSVYFRIFKARQNSNKYVVLMCSDQSRSSLKEDNDKTTYGAFVDINP 516 L ++ EEY + F + + + S+ ++N T V+ P Sbjct: 392 SLWFKGLEDPEEYLRMGFEVSAS-------SFFLDRGNSKVKFVKENPYFTNRMSVNNQP 444 Query: 517 HQP------LSLRALIDHSVVESFGGKGRACITSRVYPKLAIGKSS 556 + + L+D +++E + G T+ + S Sbjct: 445 FKSENDLSYYKVYGLLDQNILELYFNDGDVVSTNTYFMTTGNALGS 490 >4FFH-A nrPDB Length = 492 Score = 258 bits (658), Expect = 6e-69, Method: Composition-based stats. Identities = 110/527 (20%), Positives = 182/527 (34%), Gaps = 99/527 (18%) Query: 55 FHFQPPKNWMNDPNGPMIYKGIYHLFY----QWNPKGAVWGNIVWAHSTSTDLINWDPHP 110 +H PP W+ +P P+ G Y L+Y Q N G W H+++TD + + H Sbjct: 4 YHMTPPSGWLCNPQRPVTTHGAYQLYYLHSDQNNGPGG------WDHASTTDGVAFTHHG 57 Query: 111 PAIFPSAPFDINGCWSGSATIL-------PNGKPVILYT----GIDPKNQQVQNIAEPKN 159 + P P WSGSA + G V L T G+ +Q + Sbjct: 58 -TVMPLRP--DFPVWSGSAVVDTANTAGFGAGAVVALATQPTDGVRKYQEQYLYWSTDGG 114 Query: 160 LSDPYLREWKKSPLNPLMAPDAVNGINASSFRDPTTAWLGQDKKWRVIIGSKIHRRGLAI 219 + L + + A NA FRDP W +W +IG R A Sbjct: 115 FTFTALPDPVIVNTDGRAATTPAEIENAEWFRDPKIHWDTARGEWVCVIG----RLRYAA 170 Query: 220 TYTSKDFLKWEKSPEPLHYDDGSGMWECPDFFPVTRFGSNGVETSSFGEPNEILKHVLKI 279 YTS + W + + G ECPD F +T + + + Sbjct: 171 FYTSPNLRDWTLRRNFDYPNHALGGIECPDLFEITADDGTRHWVLAASMDAYGIGLPM-- 228 Query: 280 SLDDTKHDYYTIGTYDRVKDKFVPDNGFKMDGTAPRY-DYG-KYYASKTF--FDSAKNRR 335 + Y+T GT+D + F D P++ D+G +YA+ T+ D+ + +R Sbjct: 229 -----TYAYWT-GTWDGEQ--------FHADDLTPQWLDWGWDWYAAVTWPSIDAPETKR 274 Query: 336 ILWGWTNESSS----VEDDVEKGWSGIQTIPRKIWLDRSGKQ---LIQWPVREVERLRTK 388 + W N V D G++G +I R++ L R L+ PV + T Sbjct: 275 LAIAWMNNWKYAARDVPTDASDGYNGQNSIVRELRLARQPGGWYTLLSTPVAALTNYVTA 334 Query: 389 QVKNLRNKVLKSGSRLEVYGVTAAQADVEVLFKVRDLEKADVIEPSWTDPQLICSKMNVS 448 V GS + + A + ++++ + Sbjct: 335 TTTLPDRTV--DGSAVLPWNGRAYEIELDIAWDTATN----------------------- 369 Query: 449 VKSGLGPFGLMVLASKNLEEYTSVYFRIFKARQNSNKYVVLMCSDQSRSSLKEDNDKTTY 508 G+ V S + +T++ KY + D+ S L + Sbjct: 370 -------VGISVGRSPDGTRHTNI-----------GKYGADLYVDRGPSDLAGYSLAPYS 411 Query: 509 GAFVDINPH-QPLSLRALIDHSVVESFGGKGRACITSRVYPKLAIGK 554 A I+P + + LR L+D VE F G ++ +V+ Sbjct: 412 RAAAPIDPGARSVHLRILVDTQSVEVFVNAGHTVLSQQVHFAEGDTG 458 >5XH8-A nrPDB Length = 605 Score = 115 bits (288), Expect = 4e-26, Method: Composition-based stats. Identities = 105/602 (17%), Positives = 199/602 (33%), Gaps = 102/602 (16%) Query: 46 SVNQPYRTGFHFQPPKNWMNDPNGPMIY-----KGIYHLFYQWNPKGAVWGNIVWAHSTS 100 S+ + +R H PP + DP ++ G++H+ + + G +T+ Sbjct: 21 SLFETWRPRAHVLPPNGQIGDP---CLHYTDPATGLFHVGFLHDGSGIS-------SATT 70 Query: 101 TDLINWDPHPP---AIFPSAPFDINGCWSGSATILP-NGKPVILYTGID----------P 146 DL + I P D + GS NG P +LYT + Sbjct: 71 DDLATYQDLNQGNQVIVPGGINDPVAVFDGSVIPNGINGLPTLLYTSVSYLPIHWSIPYT 130 Query: 147 KNQQVQNIAEPKNLSDPYLREWKKSPLNPLMAPDAVNGINASSFRDPTTA--------WL 198 + + Q++A +S + K P++ P N ++FRDP Sbjct: 131 RGSETQSLA----VSSDGGSNFTKLDQGPVI-PGPPFAYNVTAFRDPYVFQNPTLDSLLH 185 Query: 199 GQDKKWRVIIGSKIHRRG----LAITYTSKDFLKWEKS----PEPLHYDDGSGMW----- 245 ++ W +I +H +G L Y S DF WE EP + G+G W Sbjct: 186 SKNNTWYTVISGGLHEKGPAQFLYRQYDS-DFQYWEYLGQWWHEPTNSTWGNGTWAGRWA 244 Query: 246 ---ECPDFFPVTRFGSNGVETSSFGEPNEILKHVLKISLDDTKHDYYTIGTYDRVKD-KF 301 E + F + +G N E + L + GT R F Sbjct: 245 FNFETGNVFSLDEYGYNPHGQIFTTIGTEGSDLPVVPQLTSIHDMLWVSGTVSRNGSVSF 304 Query: 302 VPDNGFKMDGTAPRYDYG-KYYASKTFF----------DSAKNRRILWGWTN----ESSS 346 P A D+G YA+ A +R I + W + E + Sbjct: 305 NP-------NMAGFLDWGFSSYAAAGKVLPSTSLPSTKSGAPDRFISYVWLSGDLFEQAE 357 Query: 347 VEDDVEKGWSGIQTIPRKIWLDRSGKQLIQWPVREVERLRTKQVKNLRNKVLKSGSRLEV 406 ++ W+G +PR++ + ++ + + V + + L + Sbjct: 358 GFPTNQQNWTGTLLLPRELRVLYI-PNVVDNALARESGASWQVVSSDGSAGTVELQTLGI 416 Query: 407 YGVTAAQADV--EVLFKVRDLEK-ADVIEPSWTDPQLICSKMNV------SVKSGLGPFG 457 +A + F + + P P ++ S + G Sbjct: 417 SIARETKAALLSGTSFTESGRTLNSSGVVPFKRSPSEKFFVLSAQLSFPASARGSGLKSG 476 Query: 458 LMVLASKNLEEYTSVYFRIFKARQNSNKYVVLMCSDQSRSSLKEDNDKTTYGAFVDINPH 517 +L+S++ E T+VY++ ++ + ++ + + F +N Sbjct: 477 FQILSSEH--ESTTVYYQFSNESIIVDRSNT-SAAARTTDGIDSSAEAGKLRLFDVLNGG 533 Query: 518 Q----PLSLRALIDHSVVESFGGKGRACITSRVYPKLAIGKSSHLFAFNYGYQSVDVLNL 573 + L L ++D+SV+E + GR +++ V A ++ F+ G V + Sbjct: 534 EQAIETLDLTLVVDNSVLEVYAN-GRFALSTWVRSWYANST--NISFFHNGVGGVAFSKV 590 Query: 574 NA 575 Sbjct: 591 TV 592 >3LFI-A nrPDB Length = 634 Score = 96.9 bits (239), Expect = 2e-20, Method: Composition-based stats. Identities = 97/621 (15%), Positives = 190/621 (30%), Gaps = 119/621 (19%) Query: 51 YRTGFHFQPPKNWMNDPNGPMIY--KGIYHLFYQWNPKGAVWGNIVWAHSTSTDLINWDP 108 +R H P + + DP G++H+ + + G G +T TD D Sbjct: 26 WRPRAHILPAEGQIGDPCAHYTDPSTGLFHVGFLHDGDGIA-GATTANLATYTDTS--DN 82 Query: 109 HPPAIFPSAPFDINGCWSGSAT-ILPNGKPVILYTGID----------PKNQQVQNIAEP 157 I P D + G+ + N P +LYT + + + Q++A Sbjct: 83 GSFLIQPGGKNDPVAVFDGAVIPVGVNNTPTLLYTSVSFLPIHWSIPYTRGSETQSLA-- 140 Query: 158 KNLSDPYLREWKKSPLNPLMAPDAVNGINASSFRDPTTA--------------------- 196 ++ R + K P++A ++ ++FRDP Sbjct: 141 --VARDGGRRFDKLDQGPVIADH-PFAVDVTAFRDPFVFRSARLDVLLSLDEEVARNETA 197 Query: 197 -------WLGQDKKWRVIIGSKIHRRGLA-ITY-----TSKDFLKWEK-----SPEPLHY 238 W ++ W V + +H G A Y + +F WE Sbjct: 198 VQQAVDGWTEKNAPWYVAVSGGVHGVGPAQFLYRQNGGNASEFQYWEYLGEWWQEATNSS 257 Query: 239 DDGSGMW--------ECPDFFPVTRFGSNGVETSSFGEPNEILKHVLKISLDDTKHD-YY 289 G W E + +T G + F + + + HD + Sbjct: 258 WGDEGTWAGRWGFNFETGNVLFLTEEGHDPQTGEVFVTLGTEGSGLPIVPQVSSIHDMLW 317 Query: 290 TIGTYDRVKDKFVPDNGFKMDGTAPRYDYG-KYYASKTFF-----------DSAKNRRIL 337 G ++ F A D+G YA+ +R + Sbjct: 318 AAGEVGVGSEQEGAKVEFS-PSMAGFLDWGFSAYAAAGKVLPASSAVSKTSGVEVDRYVS 376 Query: 338 WGWTNESSSVEDD----VEKGWSGIQTIPRKIWLDRSGKQL---------IQWPVREVER 384 + W + D ++GW+G +PR++ + + + W V E + Sbjct: 377 FVWLTGDQYEQADGFPTAQQGWTGSLLLPRELKVQTVENVVDNELVREEGVSWVVGESDN 436 Query: 385 LRTKQVKNLRNKVLKSGSRLEVYGVTAAQADVEVLFKVRDLEKADVIEPSWTDPQLICSK 444 +T ++ L + + + + V + + + P P Sbjct: 437 -QTATLRTLGITIARETKAALLANGS-------VTAEEDRTLQTAAVVPFAQSPSSKFFV 488 Query: 445 MN------VSVKSGLGPFGLMVLASKNLEEYTSVYFRIFKARQNSNKYVVLMCSDQSRSS 498 + S +S G +LAS+ E T++Y++ ++ + + Sbjct: 489 LTAQLEFPASARSSPLQSGFEILASE--LERTAIYYQFSNESLVVDRSQT-SAAAPTNPG 545 Query: 499 LKEDNDKTTYGAFVDINPH----QPLSLRALIDHSVVESFGGKGRACITSRVYPKLAIGK 554 L + F I + L L ++D++VVE + GR +++ Sbjct: 546 LDSFTESGKLRLFDVIENGQEQVETLDLTVVVDNAVVEVYAN-GRFALSTWARSWYDNST 604 Query: 555 SSHLFAFNYGYQSVDVLNLNA 575 F+ G V N++ Sbjct: 605 QIRF--FHNGEGEVQFRNVSV 623 >3R4Z-A nrPDB Length = 374 Score = 39.5 bits (90), Expect = 0.005, Method: Composition-based stats. Identities = 29/130 (22%), Positives = 47/130 (36%), Gaps = 17/130 (13%) Query: 66 DPNGPMIYKGIYHLFY-----------QWNPKGAV--WGNIVWAHSTSTDLINWDPHPPA 112 DP+ + YH++Y NP+ V W H+TS D I W PA Sbjct: 52 DPSAVLKVDDEYHVWYTKGEGETVGFGSDNPEDKVFPWDKTEVWHATSKDKITWKEIGPA 111 Query: 113 I--FPSAPFDINGCWSGSATILPNGKPVILYTGIDPKNQQVQNIAEPKNLSDPYLREWKK 170 I + +D ++ + NG ++Y + SD W K Sbjct: 112 IQRGAAGAYDDRAVFT-PEVLRHNGTYYLVYQTVKAPYLNRSLEHIAIAYSDSPFGPWTK 170 Query: 171 SPLNPLMAPD 180 S P+++P+ Sbjct: 171 SDA-PILSPE 179 >5A7V-A nrPDB Length = 388 Score = 37.6 bits (85), Expect = 0.014, Method: Composition-based stats. Identities = 31/232 (13%), Positives = 59/232 (25%), Gaps = 32/232 (13%) Query: 96 AHSTSTDLINWD-PHPPAIFPSAPFDINGCWSGSATILPNGKPVILYTGIDPKNQQVQNI 154 ++TS+D I++ P +P W G P + Q ++I Sbjct: 110 GYATSSDGIHFKREKTPVFYPDNDTQKKLEWPGGCE-DPRIAVTAEGLYVMTYTQWNRHI 168 Query: 155 AEPKNLSDPYLREWKKSPLNPLMAPD---------AVNGINASSFRDPTTAWLGQDKKWR 205 + L++W K P A +G + + D K+ Sbjct: 169 PRLAIATSRNLKDWTKHG--PAFAKAYDGKFFNLGCKSGSILTEVVNGKQVIKKIDGKYF 226 Query: 206 VIIGSKIHRRGLAITYTSKDFLKWEKSPEPLHY----------DDGSGMWECPDFFPVTR 255 + G + TS+D + W S + EC Sbjct: 227 MYWGEEH-----VFAATSEDLVNWTPYVNTDGSLRKLFSPRDGHFDSQLTEC----GPPA 277 Query: 256 FGSNGVETSSFGEPNEILKHVLKISLDDTKHDYYTIGTYDRVKDKFVPDNGF 307 + + N + + + + D + D F Sbjct: 278 IYTPKGIVLLYNGKNSASRGDKRYTANVYAAGQALFDANDPTRFITRLDEPF 329 Score = 30.3 bits (66), Expect = 2.5, Method: Composition-based stats. Identities = 32/164 (19%), Positives = 53/164 (32%), Gaps = 27/164 (16%) Query: 73 YKGIYHLFYQWNPKGAVWGNIVWAHSTSTDLINWDPHPPAIFPSAP--FDINGCWSGS-- 128 G Y ++ WG +TS DL+NW P+ +G + Sbjct: 221 IDGKYFMY---------WGEEHVFAATSEDLVNWTPYVNTDGSLRKLFSPRDGHFDSQLT 271 Query: 129 -----ATILPNGKPVILYTGIDPKNQQVQN-----IAEPKNLSDPYLREWKKSPLNPLMA 178 A P G V+LY G + ++ + A + L D + L+ Sbjct: 272 ECGPPAIYTPKG-IVLLYNGKNSASRGDKRYTANVYAAGQALFDANDPTRFITRLDEPFF 330 Query: 179 PDAVNGINASSFRDPTTAWLGQ---DKKWRVIIGSKIHRRGLAI 219 + + + D T G KW + G + G+AI Sbjct: 331 RPMDSFEKSGQYVDGTVFIEGMVYYKDKWYLYYGCADSKVGMAI 374 >3P2N-A nrPDB Length = 408 Score = 37.6 bits (85), Expect = 0.015, Method: Composition-based stats. Identities = 55/321 (17%), Positives = 98/321 (30%), Gaps = 52/321 (16%) Query: 66 DPNGPMIYKGIYHLFYQWN--PKGAVWGNIV------WA-----HSTSTDLINWDPHPPA 112 DP+ + G Y+++Y + P G+I W ++TS D W PA Sbjct: 97 DPSAIIKENGKYYVWYSKSTGPTQGFGGDIEKDKVFPWDRCDIWYATSEDGWTWKEEGPA 156 Query: 113 I--FPSAPFDINGCWSGSATILPNGKPVILYTGIDPKNQQVQN---IAEPKNLSDPYLR- 166 + +D ++ + + T P N +V+N +A + P+ + Sbjct: 157 VTRGEKGAYDDRSVFTVEIMKWEDKYYLCYQTVKSPYNVRVKNQVGLAWADSPDGPWTKS 216 Query: 167 -EWKKSPLNPLMAPDAVNGI---------NASSFRDPTT------AWLGQDKKWR---VI 207 E SP + + ++ DP +L + + Sbjct: 217 EEPILSPADNGVWKGEEQDRFAVIKKGDFDSHKVHDPCIIPYKGKFYLYYKGEQMGEAIT 276 Query: 208 IGSKIHRRGLAITYTSKDFLKWEKSPEPLHYDDGSGMWECPDFFPVTRFGSNGVETSSFG 267 G + R G+AI D K P + SG C G ++ G Sbjct: 277 FGGRQIRHGVAI----ADNPKGPYVKSPYNPISNSGHEICV----WPYNGGIASLITTDG 328 Query: 268 EPNEILKHV-----LKISLDDTKHDYYTIGTYDRVKDKFVPDNGFKMDGTAPRYDYGKYY 322 ++ +I + + IG +R D G Y+ G Y Sbjct: 329 PEKNTIQWAPDGINFEIKSVIPGVNAHAIG-LNRTADVEKEPTEILRWGLTHIYNNGDYQ 387 Query: 323 ASKTFFDSAKNRRILWGWTNE 343 + F K R + G + Sbjct: 388 SIMRFSSERKTRHVAKGVKKQ 408 >2YFT-A nrPDB Length = 571 Score = 36.8 bits (83), Expect = 0.027, Method: Composition-based stats. Identities = 16/74 (21%), Positives = 26/74 (35%), Gaps = 14/74 (18%) Query: 78 HLFYQWNPKGAVWGNIVWAHSTSTDLINWDPHPPAIFPSAPFDINGCWSGSATILPNGKP 137 H++ +N G D +W P + WSGSAT+ +G Sbjct: 163 HIYLLYNKYG------------DNDFNHWKNAGPIFG--LGTPVIQQWSGSATLNKDGSI 208 Query: 138 VILYTGIDPKNQQV 151 + YT +D + Sbjct: 209 QLYYTKVDTSDNNT 222 >3LV4-A nrPDB Length = 456 Score = 36.1 bits (81), Expect = 0.040, Method: Composition-based stats. Identities = 28/148 (18%), Positives = 51/148 (34%), Gaps = 20/148 (13%) Query: 84 NPKGAVWGNIVWAHSTSTDLINWD------PHPPAIFPS---------APFDINGCWSGS 128 N V+G+ A + STDL+NW + P+ + + W+ Sbjct: 22 NGTYYVFGS-HLASAKSTDLMNWTQISSSVHDGNPLIPNVYEELKETFEWAESDTLWAPD 80 Query: 129 ATILPNGKPVILYTGIDPKN-QQVQNIAEPKNLSDPYLRE--WKKSPLNPLMAPDAVNGI 185 T L +GK + Y + + +A ++ PY + + KS ++ + Sbjct: 81 VTQLEDGKFYMYYNACRGDSPRSALGLAVADDIEGPYKNKGIFLKSGMDGISNDGTPYDA 140 Query: 186 NAS-SFRDPTTAWLGQDKKWRVIIGSKI 212 + DP T + K W V Sbjct: 141 TKHPNVVDPHTFFDQNGKLWMVYGSYSG 168 >4AK7-A nrPDB Length = 404 Score = 34.5 bits (77), Expect = 0.12, Method: Composition-based stats. Identities = 24/144 (16%), Positives = 47/144 (32%), Gaps = 20/144 (13%) Query: 66 DPNGPMIYKGIYHLFYQ--WNPKGAVWGNIV------WA-----HSTSTDLINWDPHPPA 112 DP+ + Y+++Y + P G+I W ++TS D + W A Sbjct: 92 DPSAMLKIGDTYYVWYSKSYGPTQGFAGDIEKDKVFPWDRCDIWYATSKDGLTWKEQGIA 151 Query: 113 I--FPSAPFDINGCWSGSATILPNGKPVILYTGIDPKNQQVQNIAEPKNLSDPYLREWKK 170 + +D ++ + GK + Y + +D W K Sbjct: 152 VKRGEKGAYDDRSVFT-PEVMEWKGKYYLCYQAVKSPYTVRVKNTIGMACADSPEGLWTK 210 Query: 171 SPLNPLMAPDAV---NGINASSFR 191 + P++ P G + F+ Sbjct: 211 TD-KPVLEPSDTGEWEGDEDNRFK 233 >2UYT-A nrPDB Length = 489 Score = 34.1 bits (76), Expect = 0.15, Method: Composition-based stats. Identities = 23/148 (15%), Positives = 44/148 (29%), Gaps = 15/148 (10%) Query: 194 TTAWLGQDKKWRVIIGSKIHRRGLAITYTSKDFLKWEKSPEPLHYDDGSGMWECPDFFPV 253 W + ++ ++ S W P H + G W CP + Sbjct: 171 KMNWEYTNATTTQLVNINSDDWDESLLAWSGANKAW--FGRPTHPGNVIGHWICPQGNEI 228 Query: 254 TRFGSNGVETSSFGEPNEILKHVLKISLDDTKHDYYTIGTYDRVKDK----FVPDNGFKM 309 +T+ V+ L+ ++ Y + GT+ + + F D Sbjct: 229 PVVAVASHDTA---------SAVIASPLNGSRAAYLSSGTWSLMGFESQTPFTNDTALAA 279 Query: 310 DGTAPRYDYGKYYASKTFFDSAKNRRIL 337 + T G+Y K +R+L Sbjct: 280 NITNEGGAEGRYRVLKNIMGLWLLQRVL 307 >3QEF-A nrPDB Length = 307 Score = 34.1 bits (76), Expect = 0.17, Method: Composition-based stats. Identities = 25/138 (18%), Positives = 48/138 (34%), Gaps = 6/138 (4%) Query: 71 MIYKGIYHLFYQWN--PKGAVWGNIV-WAHSTSTDLINWDPHPPAIFPSAPFDINGCWSG 127 +++KG +L+ + P + + W +S D+ NW+ H P + G Sbjct: 18 LVHKGRVYLYAGRDEAPDNTTFFVMNEWLVYSSDDMANWEAHGPGLRAKDFTWAKGDAWA 77 Query: 128 SATILPNGKPVILYTGIDPKNQQVQNIAEPKNLSDPYLREWKKSPLNPLMAPDAVNGINA 187 S I NGK Y + + + A + D + +K + L+ D Sbjct: 78 SQVIERNGK-FYWYVTVRHDDTK-PGFAIGVAVGDSPIGPFKDALGKALITNDMTTDTPI 135 Query: 188 SSFR-DPTTAWLGQDKKW 204 DP+ + + Sbjct: 136 DWDDIDPSVFIDDDGQAY 153 >3GHG-A nrPDB Length = 562 Score = 33.8 bits (75), Expect = 0.23, Method: Composition-based stats. Identities = 12/68 (17%), Positives = 20/68 (29%), Gaps = 6/68 (8%) Query: 254 TRFGSNGVETSSFGEPNEILKHVLKISLDDTKHDYYTIGTYDRVKDKFVPDNGFKMDGTA 313 R GS G E + S+ + G + F PD+ + Sbjct: 333 PRPGSTGTWNPGSSERGSAGHWTSESSVSGST------GQWHSESGSFRPDSPGSGNARP 386 Query: 314 PRYDYGKY 321 D+G + Sbjct: 387 NNPDWGTF 394 >3ZXJ-A nrPDB Length = 542 Score = 33.4 bits (74), Expect = 0.27, Method: Composition-based stats. Identities = 81/524 (15%), Positives = 147/524 (28%), Gaps = 80/524 (15%) Query: 52 RTGFHFQPPKNWMNDPNGPMIYKGIYHLF----YQWNPKGAVWGNIVWAHSTSTDLINWD 107 R F P W + P+ + G + + ++P V S DL++W Sbjct: 3 RQASTFTNPVLWEDHPDLEVFRVGSVFYYSSSTFAYSPGAPV--------LKSYDLVHWT 54 Query: 108 PHPPAIFPSAPFDINGCWSGSATILPNGKPVILYTGIDPKNQQVQNIA---EPKNLSDPY 164 P ++ P F GS LP+G P GI + + + Sbjct: 55 PVTHSV-PRLNF-------GSNYDLPSGTPGAYVKGIWASTLRYRRSNDRFYWYGCVEGR 106 Query: 165 LREWKKSPLNPLM----APDAV-----NGINASSFRDPTTAWLGQDKKWRVIIGSKIHRR 215 W N L P + + + D D + I+ Sbjct: 107 TYLWTSPGGNALANNGEVPPSAWNWQHTATIDNCYYDAGLLIDDDDTMYIAYGNPTINVA 166 Query: 216 GLAITYTSKDFLKWEKSPEPLHYDDGSGMWECPDFFPVTRFGSNGVETSSFGEPNEILKH 275 L S D + + + ++ E + + G P + Sbjct: 167 QL-----SPDGTRQVRVQQRVYAHPQGQTVEGARMYKI-----RGNYYILVTRPADA--E 214 Query: 276 VLKISLDDTKHDYYTIGTYDRVKDKFVPDNGFKMDGTAPRYDYGKYYASKTFFDSAKNRR 335 + S + Y T + + GF G G ++ F D+ R Sbjct: 215 YVLRSTTGSPFGPYEARTLVSRIQGPLANAGFAHQGGIVDAPDGTWH-YVAFMDAYPGGR 273 Query: 336 ILWG----WTNE-SSSVEDDVEKGWSGIQTIPRKIWLDRSGKQLIQWPVREVERLRTKQV 390 I WT + V D + W IP ++ E L + + Sbjct: 274 IPVVAPLRWTADGWPEVVTDSQGRWGTSYPIP------------VRGAKNATEGLASTDL 321 Query: 391 KNLRNKVLKSGSRLEVYGVTAAQADVEVLFKVRDLEKADVIEPSWTDPQLICSKMNVSVK 450 R G+R + D F + + +I + T + + N + Sbjct: 322 DEFR------GTRFSEHWEWNHNPDTS-KFTLLGGNEGGLILRTATVTGDLFAARNTLTR 374 Query: 451 SGLGP-----FGLMVLASKNLEEYTSVYFRIFKA------RQNSNKYVVLMCSDQSRSSL 499 GP F L V ++ + +V FR A + N + V++ + Sbjct: 375 RIAGPKASGIFRLDVRGMRDGDRAGAVLFRDRAAYIGVWKQGNEARIVMVDDLRLNEDGW 434 Query: 500 KEDNDKTTYGAFVDINPHQPLSLRALIDHSVVESFGGKGRACIT 543 + + I+ + + ID + +FG T Sbjct: 435 RTASTGRVAANGPVIDTNAQQDIWLRIDADITPAFGTNTERTTT 478 >4B2O-A nrPDB Length = 286 Score = 33.4 bits (74), Expect = 0.30, Method: Composition-based stats. Identities = 23/96 (23%), Positives = 33/96 (34%), Gaps = 6/96 (6%) Query: 45 PSVNQPYRTGFHFQPPKNWMNDPNGPMIYKGIYHLFYQWNPKGAVWGNIVWAHSTSTDLI 104 P + Y+ HF N +G + + IYH Q GN W D I Sbjct: 23 PKLKTKYKP--HFTIING-ENAAHGKGLTEKIYHSLIQSGADAITMGNHTWDKKEIFDFI 79 Query: 105 NWDPHPPAIFPSAPFDINGCWSGSATILPNGKPVIL 140 D P + P+ F G + NGK + + Sbjct: 80 --DDVPNLVRPAN-FPEGTPGKGITYVKANGKELAV 112 >2WLX-A nrPDB Length = 423 Score = 33.4 bits (74), Expect = 0.31, Method: Composition-based stats. Identities = 21/113 (18%), Positives = 36/113 (31%), Gaps = 9/113 (7%) Query: 80 FYQWNPKGAVWGNIVWAHSTSTDLINWDP-HPPAIFPSAPFDINGCWSGSATILPNGKPV 138 Y + W H+ S D + + H P + DI W A + + V Sbjct: 305 GYSYIKPKGEIAGARWGHAGS-DSTHMEDFHNPDGTMRSADDITAMWK--AWNIKPEQQV 361 Query: 139 ILYTGIDPKNQQVQNIA-----EPKNLSDPYLREWKKSPLNPLMAPDAVNGIN 186 Y G + + A + ++ D EW P NP+ + + Sbjct: 362 SFYCGTGWRASETFMYARAMGWKNVSVYDGGWYEWSSDPKNPVATGERGPDSS 414 >3C7F-A nrPDB Length = 487 Score = 33.0 bits (73), Expect = 0.33, Method: Composition-based stats. Identities = 37/241 (15%), Positives = 58/241 (24%), Gaps = 51/241 (21%) Query: 71 MIYKGIYHLF-----YQWNPKGAVWGNIVWA-----HSTSTDLINWDPHP----PAIFPS 116 + Y G +++ Y++N G + N +S D++NW H + Sbjct: 28 LTYNGRVYIYMSSDDYEYNSNGTIKDNSFANLNRVFVISSADMVNWTDHGAIPVAGANGA 87 Query: 117 APFDINGCWSGS------ATILPNGK-PVILYTGIDPKNQQVQNIAEPKNLSDPYLREWK 169 W+G+ A NGK LY V +D + W Sbjct: 88 NGGRGIAKWAGASWAPSIAVKKINGKDKFFLYFANSGGGIGVLT-------ADSPIGPWT 140 Query: 170 KSPLNPLMAPDAVNGINASSFRDPTTAWLGQDKKWRVIIGSKIHRRGLAITYTSKDFLKW 229 PL+ P DP + G Sbjct: 141 DPIGKPLVTPSTPGMSGVVWLFDPAVFVDDDGTGYLYAGGG------------------- 181 Query: 230 EKSPEPLHYDDGSGMWECPDFFPVTRFGSNGVETSSFGEPNEILKHVLKISLDDTKHDYY 289 P + G W P V + G + + L YY Sbjct: 182 ----VPGVSNPTQGQWANPKTARVIKLGPDMTSVVGSASTIDAPFMFEDSGLHKYNGTYY 237 Query: 290 T 290 Sbjct: 238 Y 238 >3IB3-A nrPDB Length = 560 Score = 33.0 bits (73), Expect = 0.41, Method: Composition-based stats. Identities = 25/205 (12%), Positives = 56/205 (27%), Gaps = 21/205 (10%) Query: 140 LYTGIDPKNQQVQNIAEPKNLSDPYLR---EWKKSPLNPLMAPDAVNGINASSFRDPTTA 196 Y I+ Q + YL W S P + +R+ A Sbjct: 146 YYEVIEWAANQSWSNGNIGTNGVSYLAVTQWWVASLNPPHLKAMIPWEGLNDMYRE--VA 203 Query: 197 WLGQDKKWRVIIGSKIHRRGLAITYTSKDFLKWEKSPEPLHYDDGSGMWECP---DFFPV 253 + I G +T F +W P D E P DF+ Sbjct: 204 FH-----------GGIPDTGFYRFWTQGIFARWT--DNPNIEDLIQAQQEHPLFDDFWKQ 250 Query: 254 TRFGSNGVETSSFGEPNEILKHVLKISLDDTKHDYYTIGTYDRVKDKFVPDNGFKMDGTA 313 + + ++T + + + + + + V + ++ + + Sbjct: 251 RQVPLSQIKTPLLTCASWSTQGLHNRGSFEGFKQAASEEKWLYVHGRKEWESYYARENLE 310 Query: 314 PRYDYGKYYASKTFFDSAKNRRILW 338 + + +Y + D +++ Sbjct: 311 RQKSFFDFYLKEENNDWKDTPHVIY 335 >6EUG-A nrPDB Length = 374 Score = 32.6 bits (72), Expect = 0.44, Method: Composition-based stats. Identities = 14/53 (26%), Positives = 22/53 (41%), Gaps = 6/53 (11%) Query: 69 GPMIYKGIYHLFYQWNPKG---AVWGNIVWAHSTSTDLINWDPHPPAIFPSAP 118 G + ++G Y+ F + P G + +STDL NW A+ S Sbjct: 49 GILFHEGKYYWFGEHRPASGFVTEKGINCY---SSTDLYNWKSEGIALAVSEE 98 >6FRW-A nrPDB Length = 411 Score = 32.6 bits (72), Expect = 0.45, Method: Composition-based stats. Identities = 22/170 (12%), Positives = 46/170 (27%), Gaps = 10/170 (5%) Query: 99 TSTDLINWDPHPPAIFPSAPFDINGCWSGSATILPN-GKPVILYTGIDP----KNQQVQN 153 S +W + W+G+ +L + G + YT + P + + Sbjct: 102 YSRTGKDWI-FGGRVMAEGVSPTTREWAGTPILLNDEGDIDLYYTCVTPGATIAKVRGKI 160 Query: 154 IAEPKNLSDPYLREWKK-SPLNPLMAPDAVNGINASSFRDPTTAWLGQDKKWRVIIGSKI 212 + + +S + K + + +FRDP+ D K ++ + Sbjct: 161 VTSDEGVSLEGFQHVKSLFSADGKIYQTEEQNA-YWNFRDPSPFIDKNDGKLYMLFEGNV 219 Query: 213 HRRGLAITYTSKDFLKWEKSPEPLHYDDGSGMWECPDFFPVTRFGSNGVE 262 T +D P + C + E Sbjct: 220 AGSRGTHEITQEDMGS--VPPGYENVGGARYQVGCIGLAVAKDLSGDEWE 267 >4D47-A nrPDB Length = 415 Score = 32.6 bits (72), Expect = 0.50, Method: Composition-based stats. Identities = 22/181 (12%), Positives = 50/181 (27%), Gaps = 10/181 (5%) Query: 99 TSTDLINWDPHPPAIFPSAPFDINGCWSGSATILPN-GKPVILYTGIDP----KNQQVQN 153 S +W + W+G+ +L + G + YT + P + + Sbjct: 106 YSRTGKDWI-FGGRVMAEGVSPTTREWAGTPILLNDRGDIDLYYTCVTPGATIAKVRGKI 164 Query: 154 IAEPKNLSDPYLREWKKSPLNPLMAPDAVNGINASSFRDPTTAWLGQDKKWRVIIGSKIH 213 + +++S ++ +FRDP+ D K ++ + Sbjct: 165 VTSDQSVSLEGFQQVTSLFSADGTIYQTEEQNAFWNFRDPSPFIDRNDGKLYMLFEGNVA 224 Query: 214 RRGLAITYTSKDFLKWEKSPEPLHYDDGSGMWECPDFFPVTRFGSNGVETSSFGEPNEIL 273 + T + P + D G ++ +G E + Sbjct: 225 GPRGSHEITQAEMGN----VPPGYEDVGGAKYQAGCVGLAVAKDLSGSEWQILPPLITAV 280 Query: 274 K 274 Sbjct: 281 G 281 >5TA9-A nrPDB Length = 400 Score = 32.2 bits (71), Expect = 0.62, Method: Composition-based stats. Identities = 38/241 (15%), Positives = 75/241 (31%), Gaps = 50/241 (20%) Query: 66 DPNGPMIYKGIYHLFYQ--WNPKGAVWGNIV------WA-----HSTSTDLINWDPHPPA 112 DP+ + Y+++Y + G++ W ++TS D I W A Sbjct: 88 DPSAMIKVGDKYYVWYSKSYGETQGFAGDVENEKVFPWDRCDIWYATSKDGITWKEEGVA 147 Query: 113 I--FPSAPFDINGCWSGSATILPNGKPVILY-TGIDPKNQQVQN---IAEPKNLSDPYLR 166 + +D ++ + NGK + Y T P +V+ +A + P+ + Sbjct: 148 VKRGEKGAYDDRSVFT-PEVMQWNGKYYLCYQTVKSPYTVRVKENVAMAWADSPDGPWEK 206 Query: 167 EWKKSPLNPLMAPDAV---NGINASSFR-------------DPTTAWLGQDKKWRVIIGS 210 P++ P G + F+ DP + + Sbjct: 207 T-----DKPVLTPSDNGVWEGEEDNRFKVKAKGDFDSHKVHDPCIIPYNG----KFYLYY 257 Query: 211 KIHRRGLAITYTSKDFLKWEKSPEPLHYDDGSGMWECPDFFPVTRFGSNGVETSSFGEPN 270 K R G IT+ ++ D+ G + ++ P++ G G Sbjct: 258 KGERMGEEITWGGREIKH-----GVAIADNPLGPYTKSEYNPISNSGHEICVWPYKGGIA 312 Query: 271 E 271 Sbjct: 313 S 313 >3R67-A nrPDB Length = 356 Score = 32.2 bits (71), Expect = 0.64, Method: Composition-based stats. Identities = 28/147 (19%), Positives = 51/147 (34%), Gaps = 17/147 (11%) Query: 90 WGNIVWAHSTSTDLINWD-------PHPPAIFPSAP-FDINGCWSGSATILPNGKPVILY 141 WG +TSTDLINW+ I P FD + G I+ + ++LY Sbjct: 204 WGEKFVNVATSTDLINWEPMLDEKGDFLKVITPREGKFDSDLTECGPPAIMTDKGILLLY 263 Query: 142 TGIDPKNQQVQNI----AEPKNLSDPYLREWKK--SPLNPLMAPDAVNGINASSFRDPTT 195 G + + + + + ++ K L+ + + + T Sbjct: 264 NGKNKSGAEGDTLYTANSYCAGQALFDAKDPTKLIDRLDKPFYIPESDFEKSGQYPAGTV 323 Query: 196 AWLG---QDKKWRVIIGSKIHRRGLAI 219 G ++KW + G R +A+ Sbjct: 324 FIEGLVFHNQKWYLYYGCADSRVAVAV 350 Score = 31.4 bits (69), Expect = 1.0, Method: Composition-based stats. Identities = 28/130 (21%), Positives = 47/130 (36%), Gaps = 10/130 (7%) Query: 119 FDINGCWSGSATILPNGKPVILYTGIDPKNQQVQNIAEPKNLSDPYLREWKKSP--LNPL 176 ++ + ++ +ATI +GK V+LY D N V + L Y + P+ Sbjct: 46 WESSDTFNPAATI-YDGKVVVLYRAED--NSAVGIGSRTSRLGYAYSDDGLHFNRMTVPV 102 Query: 177 MAPDAVNGINASS---FRDPTTAWLGQDKKWRVIIGSKIHRRGLAITYTSKDFLKWEKSP 233 P N DP A + +D + ++ ++ TS+D WEK Sbjct: 103 FYPADDNQKELEWPGGCEDPRVA-VTEDGLYVMLYTQWNRKQARLAVATSRDLQIWEKY- 160 Query: 234 EPLHYDDGSG 243 P G Sbjct: 161 GPAFAKAYGG 170 >5A8D-A nrPDB Length = 326 Score = 31.8 bits (70), Expect = 0.75, Method: Composition-based stats. Identities = 19/119 (15%), Positives = 30/119 (25%), Gaps = 6/119 (5%) Query: 99 TSTDLINWDPHPPAIFPSAPFDINGCWSGSATILPNGKPVILYTGIDPKNQQVQNIAEPK 158 ++ DL NW H S + +I+ LY G V P Sbjct: 75 STDDLKNWTDHGEVFNAKRDSRWASV-SWAPSIVYRNNKFYLYYGNGGNGIGVAVSDSPT 133 Query: 159 NLSDPYLREWKKSPLNPLMAPDAVNGINASSFRDPTTAWLGQDKKWRVIIGSKIHRRGL 217 L S P + P DP + + G+ + + Sbjct: 134 GPFKDPLPGPLVSWNTPGVQP-----AQNMWLFDPGVFVDDDGQAYMYFGGNGQNNIRV 187 >4NOV-A nrPDB Length = 345 Score = 31.8 bits (70), Expect = 0.82, Method: Composition-based stats. Identities = 41/209 (19%), Positives = 68/209 (32%), Gaps = 33/209 (15%) Query: 66 DPNGPMIYKGIYHLFYQWNPKGAV---WGNIVWAHSTSTDLINWDPHPPAIFPSA--PFD 120 DP PM+Y +L+ + V + W ++ D++NW H D Sbjct: 56 DP-APMVYGDTLYLYTTHDEDELVNDFYTMNDWRCFSTKDMVNWTDHGAIFSLDDIGWAD 114 Query: 121 INGCWSGSATILPNGKPVILYTGIDPKNQQVQNIAEPKNLSDPYLREWKKSPLNPLMAPD 180 W+ A + NGK LY + +N + A +SD K PL+ Sbjct: 115 AR-AWAPQA-VERNGK-FYLYCPVHKRNGGM---AIAVGISDS-PTGPFKDLGYPLVDEG 167 Query: 181 AVNGINASSFRDPTTAWLGQDKKWRVIIGSKIHRRGLAITYTSKDFLKWEKSPEPLHYDD 240 N I DPT + + + + + + + + YD Sbjct: 168 DWNDI------DPTVFIDDDGQAY--------------LYFGNPELRYVLLNENMITYDK 207 Query: 241 GSGMWECPDFFPVTRFGSNGVETSSFGEP 269 G+ + P GS+ TS P Sbjct: 208 EVGIVKVPMTEEAFAKGSHDTGTSYGEGP 236 >4KCA-A nrPDB Length = 692 Score = 31.8 bits (70), Expect = 0.89, Method: Composition-based stats. Identities = 22/131 (16%), Positives = 41/131 (31%), Gaps = 13/131 (9%) Query: 158 KNLSDPYLREWKKSPLNPLMAPDAVNGINASSFRDPTTAWLGQDKKWRVIIGSKIHRRGL 217 LS L+E+ + L + + + S DP+ W K + + + + Sbjct: 93 GALSKGQLKEFLDANLAGSGSGPSTYELKRVSVHDPSIVWDPSSKTYYIFGSHRAAAK-- 150 Query: 218 AITYTSKDFLKWEKSPEP-----LHYDDGSGMWECPDFFPVTRFGSNGVETSSFGEPNEI 272 + D + W P + + +E P V G V+ +F Sbjct: 151 -----TTDLMSWTAFTAPWKTATSNNAANNVAFETPAVKKVK-KGGVDVDFPAFSATKWS 204 Query: 273 LKHVLKISLDD 283 K S+D Sbjct: 205 AKGGSGYSVDG 215 >5HX2-G nrPDB Length = 602 Score = 31.1 bits (68), Expect = 1.4, Method: Composition-based stats. Identities = 26/181 (14%), Positives = 54/181 (29%), Gaps = 17/181 (9%) Query: 288 YYTIGTYDRVKDKFVPDNGFKMDGTAPRYDYGKYYASKT----------------FFDSA 331 YY +G D G ++GK YA T + Sbjct: 34 YYELGDGDVPYSAGAWKTYNASSGQTLTAEWGKSYAINTSSGRVTINLPKGTVNDYNKVI 93 Query: 332 KNRRILWGWTNESSSVEDDVEKGWSGIQTIPRKIWLDRSGKQLIQWPVREVERLRTKQVK 391 + R + W ++ G +P +I + S +L+ E ++ KQ+ Sbjct: 94 RARDVFATWNVNPVTLVAASGDTIKGS-AVPVEINVRFSDLELVYCAPGRWEYVKNKQID 152 Query: 392 NLRNKVLKSGSRLEVYGVTAAQADVEVLFKVRDLEKADVIEPSWTDPQLICSKMNVSVKS 451 + + + + +R E Q D +F+ ++ + + + Sbjct: 153 KITSSDISNVARKEFLVEVQGQTDFLDVFRGTSYNVNNIRVKHRGNELYYGDVFSENSDF 212 Query: 452 G 452 G Sbjct: 213 G 213 >3OM6-A nrPDB Length = 456 Score = 30.7 bits (67), Expect = 1.8, Method: Composition-based stats. Identities = 19/113 (16%), Positives = 37/113 (32%), Gaps = 21/113 (18%) Query: 125 WSGSATILPNGKPVILYTGI--DPKNQQVQNIAE-------PKNLSDPYLREWK-KSPLN 174 WSGS T+ +GK + YT +Q A+ L + ++K + Sbjct: 144 WSGSGTLTKDGKVRLFYTDYSGKQYGKQTLTTAQVNMSQPNDNTLKVDGVEDYKSIFDGD 203 Query: 175 PLMAPD--------AVNGINASSFRDPTTAWLGQDK-KWRVIIGSKIHRRGLA 218 + + + + RDP ++ + K+ V + G Sbjct: 204 GKIYQTVQQFIDEGGADTGDNHTLRDP--HYIEDNGHKYLVFEANTGTEDGYQ 254 >3KST-A nrPDB Length = 306 Score = 30.7 bits (67), Expect = 1.8, Method: Composition-based stats. Identities = 7/25 (28%), Positives = 12/25 (48%) Query: 221 YTSKDFLKWEKSPEPLHYDDGSGMW 245 ++S D W++ + L D G W Sbjct: 53 FSSDDLKNWKREGQALSATDSYGTW 77 Score = 30.3 bits (66), Expect = 2.2, Method: Composition-based stats. Identities = 14/69 (20%), Positives = 25/69 (36%), Gaps = 10/69 (14%) Query: 99 TSTDLINWDPHPPAIFPSAPFDINGCWSGSATILPNGKPVILY----------TGIDPKN 148 +S DL NW A+ + + G W+ + + K L+ T P+ Sbjct: 54 SSDDLKNWKREGQALSATDSYGTWGFWAPEVYYVESKKKFYLFYSAEEHICVATSTTPEG 113 Query: 149 QQVQNIAEP 157 Q + +P Sbjct: 114 PFRQEVKQP 122 Score = 29.5 bits (64), Expect = 3.8, Method: Composition-based stats. Identities = 24/118 (20%), Positives = 46/118 (38%), Gaps = 10/118 (8%) Query: 91 GNIVWAHSTSTDLINW--DPHPPAIFPSAPFDI--NGCWSGSATILPNGKPVILYTGIDP 146 GN++W + DL++ + I +++ G + + NG ++Y+ Sbjct: 151 GNVIWVAQMTDDLMSIKTETLNQCIKAEVSWELLQGKVAEGPSLLKKNGVYYLIYSANHY 210 Query: 147 KNQQVQNIAEPKNLSDPYLREWKKSPLNPLMAPDAVNGINASSFRDPTTAWLGQDKKW 204 +N+ SD + W K NPL+ DA G+ + P + +D W Sbjct: 211 ENKGY---GVGYATSDTPMGPWVKYSKNPLLQGDAATGLVGTGHGAP---FQCKDGSW 262 >3BYN-A nrPDB Length = 473 Score = 30.3 bits (66), Expect = 2.2, Method: Composition-based stats. Identities = 22/117 (18%), Positives = 39/117 (33%), Gaps = 20/117 (17%) Query: 120 DINGCWSGSATILPNGKPVILYTGIDPKN--------QQVQNIAEPKNLSDPYLREW--- 168 D WSGSAT +GK + YT K+ QV A +L+ + ++ Sbjct: 158 DQTQEWSGSATFTSDGKIRLFYTDFSGKHYGKQTLTTAQVNVSASDSSLNINGVEDYKSI 217 Query: 169 ------KKSPLNPLMAPDAVNGINASSFRDPTTAWLGQDK-KWRVIIGSKIHRRGLA 218 + + + + + RDP ++ K+ V + G Sbjct: 218 FDGDGKTYQNVQQFIDEGNYSSGDNHTLRDP--HYVEDKGHKYLVFEANTGTEDGYQ 272 >6A8I-A nrPDB Length = 321 Score = 30.3 bits (66), Expect = 2.6, Method: Composition-based stats. Identities = 31/157 (19%), Positives = 56/157 (35%), Gaps = 26/157 (16%) Query: 63 WMNDPNGPMIYKGIYHLFYQWNPKGAVWGNIVWAHSTSTDLINWDPHPPAIFPSAP---- 118 W +DP +++F G TS D ++W+ +FPS P Sbjct: 24 WAHDPV-IAKEGSRWYVF--HTGSGIQI-------KTSEDGVHWENMG-RVFPSLPDWCK 72 Query: 119 -----FDINGCWSGSATILPNGKPVILYT-GIDPKNQQVQNIAEPKNLSDPYLREWKKSP 172 D + W+ NG + Y+ KN V +A + L DP +++ Sbjct: 73 QYVPEKDEDHLWA-PDICFYNGIYYLYYSVSTFGKNTSVIGLATNRTL-DPRDPDYEWKD 130 Query: 173 LNPLMAPDAVNGINASSFRDPTTAWLGQDKKWRVIIG 209 + P++ A + NA + P + + + W Sbjct: 131 MGPVIHSTASDNYNAIN---PNVVFDQEGQPWLSFGS 164 >5JOY-A nrPDB Length = 516 Score = 29.9 bits (65), Expect = 2.8, Method: Composition-based stats. Identities = 26/192 (13%), Positives = 52/192 (27%), Gaps = 42/192 (21%) Query: 81 YQWNPKGAVWGNIVWAHSTSTDLINWDPHPPAIFPSAPFDINGCWSGSATILP-----NG 135 +Q+ P ++ S DL++W+ + + D+ SGS P +G Sbjct: 41 FQYFPGVPLF--------HSKDLVHWEQIGNCLTRPSQLDLTNANSGSGIFAPTIRYNDG 92 Query: 136 KPVILYTGIDPKNQQV-------QNIAEPKNLSDPYLREWKKSPLNPLMAPDAVNGINAS 188 ++ T + K + +EP L + +G Sbjct: 93 VFYMITTNVSGKGNFLVHTTDPRSEWSEPVWLEQGGIDPSLYFEDGKCFMVSNPDGYINL 152 Query: 189 SFRDPTT----------------------AWLGQDKKWRVIIGSKIHRRGLAITYTSKDF 226 DP T +D + ++I G +T + Sbjct: 153 CEIDPMTGKQLSSSKRIWNGTGGRYAEGPHIYKKDGWYYLLISEGGTELGHKVTIARSRY 212 Query: 227 LKWEKSPEPLHY 238 + P + Sbjct: 213 IDGPYQGNPANP 224 >3MUN-A nrPDB Length = 693 Score = 29.9 bits (65), Expect = 2.9, Method: Composition-based stats. Identities = 13/58 (22%), Positives = 23/58 (39%), Gaps = 2/58 (3%) Query: 38 QSTNTKSPSVNQPYRTGFHFQPPKNWMNDPNGPMIYKGIYHLFYQWNPKGAVWGNIVW 95 Q+ T+ PYR + +W G + G YH F++ + N++W Sbjct: 51 QNAVTQDYLAQIPYRAAIKEKLAASWNYAKEGAPFWWGRYHYFFKNDGLQNQ--NVLW 106 >4KC7-A nrPDB Length = 474 Score = 29.9 bits (65), Expect = 3.1, Method: Composition-based stats. Identities = 24/157 (15%), Positives = 46/157 (29%), Gaps = 30/157 (19%) Query: 83 WNPKGAVWGNIVW---AH---STSTDLINWDPHPPA------IFPSAPFDING------- 123 +P GN+ + H + S DL++W+ + I P+ ++ Sbjct: 34 HDPSIIKVGNMYYVFGTHLQVAKSKDLMHWEQINTSAHDKNPIIPNINEELKETLSWART 93 Query: 124 ---CWSGSATILPNGKPVILY-TGIDPKNQQVQNIAEPKNLSDPYLREWKKSPLNPLMAP 179 W+ L +G+ + Y + IA ++ PY + + Sbjct: 94 RNDIWAPQVIQLSDGRYYMYYCASTFGSPRSAIGIAVSDDIEGPYKHYAVIVKSGQVYSV 153 Query: 180 DAV-NGINASSFR------DPTTAWLGQDKKWRVIIG 209 D R DP + + W V Sbjct: 154 DGPSEDGTPYDSRKHPNALDPGVFYDKEGNLWMVYGS 190 >4YHG-A nrPDB Length = 389 Score = 29.1 bits (63), Expect = 5.4, Method: Composition-based stats. Identities = 20/74 (27%), Positives = 27/74 (36%), Gaps = 1/74 (1%) Query: 454 GPFGLMVLASKNLEEYTSVYFRIFKARQNSNKYVVLMCSDQSRSSLKEDNDKTTYGAFVD 513 G FG + ASK EE+ YFR + L D S D A Sbjct: 294 GEFGAVRRASKADEEFRLYYFRYICKAMRDRRISALY-WDNGNSKAGNDGFGVIDHATGR 352 Query: 514 INPHQPLSLRALID 527 + ++RA+ID Sbjct: 353 FIGNGEQAVRAMID 366 >3WPZ-A nrPDB Length = 542 Score = 29.1 bits (63), Expect = 5.6, Method: Composition-based stats. Identities = 18/100 (18%), Positives = 30/100 (30%), Gaps = 16/100 (16%) Query: 113 IFPSAPFDINGCWSGSATILPNGKPVILYTGIDPKNQQVQNIAEPKNLSDPYLREWKKSP 172 IF F W+GSA + NG+ + +T + +P + K+ Sbjct: 151 IFEDQSFSHQTQWTGSARVSKNGEIKLFFTDVAFYRNSDGTNIKPYDPRIALSVGKVKAN 210 Query: 173 LNPLMAPD--------AVNGINAS--------SFRDPTTA 196 + +G +FRDP T Sbjct: 211 KKGVTLTGFNKVTDLLQADGTYYQTGAQNEFFNFRDPFTF 250 >4N4B-A nrPDB Length = 360 Score = 28.4 bits (61), Expect = 10.0, Method: Composition-based stats. Identities = 37/277 (13%), Positives = 63/277 (22%), Gaps = 38/277 (13%) Query: 106 WDPHPPAIFPSAPFDINGCWSGSATILPNGKPVILYTGIDPKNQQVQNIAEPKNLSDPYL 165 W P + P IL NG + + + P Sbjct: 28 WTSTGPLVGPKNDGRGIAGIKDPTIILINGTHHVFASTAQSAGYNLVYFTFADWADAPN- 86 Query: 166 REWKKSPLNPLMAPDAVNGINASSFRD-PTTAWLGQDKKWRVIIGSKIHRRGLAITYTSK 224 + PL + +R P W K W ++ ++ G A T+ Sbjct: 87 ATFYYLDQAPL----------GTGYRAAPQVFWFAPHKLWYLV-----YQNGNAAYSTNP 131 Query: 225 DFLKWEKSPEPLHYDDGSGMWECPDFFPVTRFGSNGVETSSFGEPNEILKHVLKISLDD- 283 D + P + + + L S D+ Sbjct: 132 DINNPKGWTAPKVFYPD-------GMPKIIEQNIGEGYWVDMWVICDSASCHLFSSDDNG 184 Query: 284 ------TKHDYYTIGTYDRVKDKFVPDNGFKMDGTAPRYDYGKYYASKTFFDSAKNRRIL 337 T + + G V N GKY + +R Sbjct: 185 QLYRSETSLEQFPNGMSQPVIAMQDNRNDLFEAACVYSLPDGKYLLLVEAIGTDGHR--- 241 Query: 338 WGWTNESSSVEDDVEKGWSGIQTIPRKIWLDRSGKQL 374 W + D + W G+ + W + Q Sbjct: 242 --WFRSWT--ADSIRGPWQGLANTEQNPWARSNNVQF 274 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.305 0.112 0.293 Lambda K H 0.267 0.0346 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 20,155,067 Number of Sequences: 36641 Number of extensions: 813064 Number of successful extensions: 2351 Number of sequences better than 10.0: 52 Number of HSP's better than 10.0 without gapping: 30 Number of HSP's successfully gapped in prelim test: 39 Number of HSP's that attempted gapping in prelim test: 2175 Number of HSP's gapped (non-prelim): 92 length of query: 584 length of database: 10,336,785 effective HSP length: 102 effective length of query: 482 effective length of database: 6,599,403 effective search space: 3180912246 effective search space used: 3180912246 T: 11 A: 40 X1: 16 ( 7.0 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 61 (28.4 bits)