BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q41951 (250 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 5I32-A nrPDB 477 e-135 2ZZ9-A nrPDB 154 2e-38 3IYZ-A nrPDB 154 3e-38 1IH5-A nrPDB 145 1e-35 3GD8-A nrPDB 144 3e-35 1YMG-A nrPDB 139 1e-33 3M9I-A nrPDB 139 1e-33 4OJ2-X nrPDB 136 7e-33 1J4N-A nrPDB 136 9e-33 4NEF-A nrPDB 136 1e-32 3D9S-A nrPDB 131 3e-31 3CLL-A nrPDB 125 2e-29 2W1P-A nrPDB 91 4e-19 2EVU-A nrPDB 88 4e-18 3LLQ-A nrPDB 69 2e-12 3NE2-A nrPDB 66 2e-11 1LDI-A nrPDB 62 2e-10 2O9F-A nrPDB 59 2e-09 6F7H-A nrPDB 52 3e-07 3C02-A nrPDB 42 2e-04 5D68-A nrPDB 33 0.15 4HDO-A nrPDB 33 0.16 4ZB4-A nrPDB 29 1.6 5LJ5-t nrPDB 29 1.6 3TDO-A nrPDB 28 5.0 >5I32-A nrPDB Length = 275 Score = 477 bits (1227), Expect = e-135, Method: Compositional matrix adjust. Identities = 249/249 (100%), Positives = 249/249 (100%) Query: 2 AGVAFGSFDDSFSLASLRAYLAEFISTLLFVFAGVGSAIAYAKLTSDAALDTPGLVAIAV 61 AGVAFGSFDDSFSLASLRAYLAEFISTLLFVFAGVGSAIAYAKLTSDAALDTPGLVAIAV Sbjct: 27 AGVAFGSFDDSFSLASLRAYLAEFISTLLFVFAGVGSAIAYAKLTSDAALDTPGLVAIAV 86 Query: 62 CHGFALFVAVAIGANISGGHVNPAVTFGLAVGGQITVITGVFYWIAQLLGSTAACFLLKY 121 CHGFALFVAVAIGANISGGHVNPAVTFGLAVGGQITVITGVFYWIAQLLGSTAACFLLKY Sbjct: 87 CHGFALFVAVAIGANISGGHVNPAVTFGLAVGGQITVITGVFYWIAQLLGSTAACFLLKY 146 Query: 122 VTGGLAVPTHSVAAGLGSIEGVVMEIIITFALVYTVYATAADPKKGSLGTIAPLAIGLIV 181 VTGGLAVPTHSVAAGLGSIEGVVMEIIITFALVYTVYATAADPKKGSLGTIAPLAIGLIV Sbjct: 147 VTGGLAVPTHSVAAGLGSIEGVVMEIIITFALVYTVYATAADPKKGSLGTIAPLAIGLIV 206 Query: 182 GANILAAGPFSGGSMNPARSFGPAVAAGDFSGHWVYWVGPLIGGGLAGLIYGNVFMGSSE 241 GANILAAGPFSGGSMNPARSFGPAVAAGDFSGHWVYWVGPLIGGGLAGLIYGNVFMGSSE Sbjct: 207 GANILAAGPFSGGSMNPARSFGPAVAAGDFSGHWVYWVGPLIGGGLAGLIYGNVFMGSSE 266 Query: 242 HVPLASADF 250 HVPLASADF Sbjct: 267 HVPLASADF 275 >2ZZ9-A nrPDB Length = 301 Score = 154 bits (390), Expect = 2e-38, Method: Compositional matrix adjust. Identities = 97/239 (40%), Positives = 139/239 (58%), Gaps = 11/239 (4%) Query: 8 SFDDSFSLASLRAYLAEFISTLLFVFAGVGSAIAYAKLTSDAALDTPGLVAIAVCHGFAL 67 +F ++ A +A AEF++ L+FV VGS I + + +D +V I++C G ++ Sbjct: 3 AFKGVWTQAFWKAVTAEFLAMLIFVLLSVGSTINWGGSENPLPVD---MVLISLCFGLSI 59 Query: 68 FVAVAIGANISGGHVNPAVTFGLAVGGQITVITGVFYWIAQLLGSTAACFLLKYVT---- 123 V +ISGGH+NPAVT + +I++ VFY AQ LG+ +L VT Sbjct: 60 ATMVQCFGHISGGHINPAVTVAMVCTRKISIAKSVFYITAQCLGAIIGAGILYLVTPPSV 119 Query: 124 -GGLAVPTHSVAAGLGSIEGVVMEIIITFALVYTVYATAADPKKGSLGTIAPLAIGLIVG 182 GGL V T V L + G+++E+IITF LV+T++A+ D + G++A LAIG V Sbjct: 120 VGGLGVTT--VHGNLTAGHGLLVELIITFQLVFTIFASCDDKRTDVTGSVA-LAIGFSVA 176 Query: 183 ANILAAGPFSGGSMNPARSFGPAVAAGDFSGHWVYWVGPLIGGGLAGLIYGNVFMGSSE 241 L A ++G SMNPARSFGPAV G++ HW+YWVGP+IG LAG +Y VF E Sbjct: 177 IGHLFAINYTGASMNPARSFGPAVIMGNWENHWIYWVGPIIGAVLAGALYEYVFCPDVE 235 >3IYZ-A nrPDB Length = 340 Score = 154 bits (389), Expect = 3e-38, Method: Compositional matrix adjust. Identities = 97/239 (40%), Positives = 139/239 (58%), Gaps = 11/239 (4%) Query: 8 SFDDSFSLASLRAYLAEFISTLLFVFAGVGSAIAYAKLTSDAALDTPGLVAIAVCHGFAL 67 +F ++ A +A AEF++ L+FV VGS I + + +D +V I++C G ++ Sbjct: 42 AFKGVWTQAFWKAVTAEFLAMLIFVLLSVGSTINWGGSENPLPVD---MVLISLCFGLSI 98 Query: 68 FVAVAIGANISGGHVNPAVTFGLAVGGQITVITGVFYWIAQLLGSTAACFLLKYVT---- 123 V +ISGGH+NPAVT + +I++ VFY AQ LG+ +L VT Sbjct: 99 ATMVQCFGHISGGHINPAVTVAMVCTRKISIAKSVFYITAQCLGAIIGAGILYLVTPPSV 158 Query: 124 -GGLAVPTHSVAAGLGSIEGVVMEIIITFALVYTVYATAADPKKGSLGTIAPLAIGLIVG 182 GGL V T V L + G+++E+IITF LV+T++A+ D + G++A LAIG V Sbjct: 159 VGGLGVTT--VHGNLTAGHGLLVELIITFQLVFTIFASCDDKRTDVTGSVA-LAIGFSVA 215 Query: 183 ANILAAGPFSGGSMNPARSFGPAVAAGDFSGHWVYWVGPLIGGGLAGLIYGNVFMGSSE 241 L A ++G SMNPARSFGPAV G++ HW+YWVGP+IG LAG +Y VF E Sbjct: 216 IGHLFAINYTGASMNPARSFGPAVIMGNWENHWIYWVGPIIGAVLAGALYEYVFCPDVE 274 >1IH5-A nrPDB Length = 269 Score = 145 bits (367), Expect = 1e-35, Method: Compositional matrix adjust. Identities = 89/217 (41%), Positives = 127/217 (58%), Gaps = 4/217 (1%) Query: 19 RAYLAEFISTLLFVFAGVGSAIAYAKLTSDAALDTPGLVAIAVCHGFALFVAVAIGANIS 78 RA +AEF++T LFVF +GSA+ + + V +++ G ++ +IS Sbjct: 12 RAVVAEFLATTLFVFISIGSALGFKYPVGNNQTAVQDNVKVSLAFGLSIATLAQSVGHIS 71 Query: 79 GGHVNPAVTFGLAVGGQITVITGVFYWIAQLLGSTAACFLLKYVTGGL---AVPTHSVAA 135 G H+NPAVT GL + QI++ + Y IAQ +G+ A +L +T L ++ + +A Sbjct: 72 GAHLNPAVTLGLLLSCQISIFRALMYIIAQCVGAIVATAILSGITSSLTGNSLGRNDLAD 131 Query: 136 GLGSIEGVVMEIIITFALVYTVYATAADPKKGSLGTIAPLAIGLIVGANILAAGPFSGGS 195 G+ S +G+ +EII T LV V AT D ++ LG APLAIGL V L A ++G Sbjct: 132 GVNSGQGLGIEIIGTLQLVLCVLATT-DRRRRDLGGSAPLAIGLSVALGHLLAIDYTGCG 190 Query: 196 MNPARSFGPAVAAGDFSGHWVYWVGPLIGGGLAGLIY 232 +NPARSFG AV +FS HW++WVGP IGG LA LIY Sbjct: 191 INPARSFGSAVITHNFSNHWIFWVGPFIGGALAVLIY 227 >3GD8-A nrPDB Length = 223 Score = 144 bits (364), Expect = 3e-35, Method: Compositional matrix adjust. Identities = 92/223 (41%), Positives = 130/223 (58%), Gaps = 11/223 (4%) Query: 19 RAYLAEFISTLLFVFAGVGSAIAYAKLTSDAALDTPGLVAIAVCHGFALFVAVAIGANIS 78 +A AEF++ L+FV +GS I + +D +V I++C G ++ V +IS Sbjct: 5 KAVTAEFLAMLIFVLLSLGSTINWGGTEKPLPVD---MVLISLCFGLSIATMVQCFGHIS 61 Query: 79 GGHVNPAVTFGLAVGGQITVITGVFYWIAQLLGSTAACFLLKYVT-----GGLAVPTHSV 133 GGH+NPAVT + +I++ VFY AQ LG+ +L VT GGL V V Sbjct: 62 GGHINPAVTVAMVCTRKISIAKSVFYIAAQCLGAIIGAGILYLVTPPSVVGGLGVTM--V 119 Query: 134 AAGLGSIEGVVMEIIITFALVYTVYATAADPKKGSLGTIAPLAIGLIVGANILAAGPFSG 193 L + G+++E+IITF LV+T++A+ + G+IA LAIG V L A ++G Sbjct: 120 HGNLTAGHGLLVELIITFQLVFTIFASCDSKRTDVTGSIA-LAIGFSVAIGHLFAINYTG 178 Query: 194 GSMNPARSFGPAVAAGDFSGHWVYWVGPLIGGGLAGLIYGNVF 236 SMNPARSFGPAV G++ HW+YWVGP+IG LAG +Y VF Sbjct: 179 ASMNPARSFGPAVIMGNWENHWIYWVGPIIGAVLAGGLYEYVF 221 >1YMG-A nrPDB Length = 263 Score = 139 bits (350), Expect = 1e-33, Method: Compositional matrix adjust. Identities = 86/222 (38%), Positives = 128/222 (57%), Gaps = 21/222 (9%) Query: 19 RAYLAEFISTLLFVFAGVGSAIAYAKLTSDAALDTPG---LVAIAVCHGFALFVAVAIGA 75 RA AEF ++L +VF G+G+++ +A PG ++ +A+ G AL V Sbjct: 11 RAICAEFFASLFYVFFGLGASLRWA----------PGPLHVLQVALAFGLALATLVQAVG 60 Query: 76 NISGGHVNPAVTFGLAVGGQITVITGVFYWIAQLLGSTAACFLLKYVT-----GGLAVPT 130 +ISG HVNPAVTF VG Q++++ + Y +AQLLG+ A +L VT G LA+ T Sbjct: 61 HISGAHVNPAVTFAFLVGSQMSLLRAICYMVAQLLGAVAGAAVLYSVTPPAVRGNLALNT 120 Query: 131 HSVAAGLGSIEGVVMEIIITFALVYTVYATAADPKKGSLGTIAPLAIGLIVGANILAAGP 190 +G + ++EI +T V ++AT + + G LG++A LA+G + L Sbjct: 121 LHPGVSVG--QATIVEIFLTLQFVLCIFATYDERRNGRLGSVA-LAVGFSLTLGHLFGMY 177 Query: 191 FSGGSMNPARSFGPAVAAGDFSGHWVYWVGPLIGGGLAGLIY 232 ++G MNPARSF PA+ +F+ HWVYWVGP+IG GL L+Y Sbjct: 178 YTGAGMNPARSFAPAILTRNFTNHWVYWVGPVIGAGLGSLLY 219 >3M9I-A nrPDB Length = 220 Score = 139 bits (350), Expect = 1e-33, Method: Compositional matrix adjust. Identities = 87/222 (39%), Positives = 128/222 (57%), Gaps = 21/222 (9%) Query: 19 RAYLAEFISTLLFVFAGVGSAIAYAKLTSDAALDTPG---LVAIAVCHGFALFVAVAIGA 75 RA AEF +TL +VF G+G+++ +A PG ++ +A+ G AL V Sbjct: 5 RAIFAEFFATLFYVFFGLGASLRWA----------PGPLHVLQVALAFGLALATLVQAVG 54 Query: 76 NISGGHVNPAVTFGLAVGGQITVITGVFYWIAQLLGSTAACFLLKYVT-----GGLAVPT 130 +ISG HVNPAVTF VG Q++++ + Y +AQLLG+ A +L VT G LA+ T Sbjct: 55 HISGAHVNPAVTFAFLVGSQMSLLRAICYVVAQLLGAVAGAAVLYSVTPPAVRGNLALNT 114 Query: 131 HSVAAGLGSIEGVVMEIIITFALVYTVYATAADPKKGSLGTIAPLAIGLIVGANILAAGP 190 +G + ++EI +T V ++AT + + G LG++A LA+G + L Sbjct: 115 LHPGVSVG--QATIVEIFLTLQFVLCIFATYDERRNGRLGSVA-LAVGFSLTLGHLFGMY 171 Query: 191 FSGGSMNPARSFGPAVAAGDFSGHWVYWVGPLIGGGLAGLIY 232 ++G MNPARSF PA+ +F+ HWVYWVGP+IG GL L+Y Sbjct: 172 YTGAGMNPARSFAPAILTRNFTNHWVYWVGPVIGAGLGSLLY 213 >4OJ2-X nrPDB Length = 274 Score = 136 bits (343), Expect = 7e-33, Method: Compositional matrix adjust. Identities = 91/230 (39%), Positives = 128/230 (55%), Gaps = 19/230 (8%) Query: 14 SLASLRAYLAEFISTLLFVFAGVGSAIAYAKLTSDAALDTPGLVAIAVCHGFALFVAVAI 73 S+A RA AEF++TLLFVF G+GSA+ + + P ++ IA+ G + V Sbjct: 9 SIAFSRAVFAEFLATLLFVFFGLGSALNWPQ-------ALPSVLQIAMAFGLGIGTLVQA 61 Query: 74 GANISGGHVNPAVTFGLAVGGQITVITGVFYWIAQLLGSTAACFLLKYVT-----GGLAV 128 +ISG H+NPAVT VG ++V+ FY AQLLG+ A LL +T G LAV Sbjct: 62 LGHISGAHINPAVTVACLVGCHVSVLRAAFYVAAQLLGAVAGAALLHEITPADIRGDLAV 121 Query: 129 P--THSVAAGLGSIEGVVMEIIITFALVYTVYATAADPKKGSLGTIAPLAIGLIVGANIL 186 ++S AG + V +E+ +T LV ++A+ + + + GT A L+IG V L Sbjct: 122 NALSNSTTAG----QAVTVELFLTLQLVLCIFASTDERRGENPGTPA-LSIGFSVALGHL 176 Query: 187 AAGPFSGGSMNPARSFGPAVAAGDFSGHWVYWVGPLIGGGLAGLIYGNVF 236 ++G SMNPARS PAV G F HWV+W+GPL+G L L+Y V Sbjct: 177 LGIHYTGCSMNPARSLAPAVVTGKFDDHWVFWIGPLVGAILGSLLYNYVL 226 >1J4N-A nrPDB Length = 271 Score = 136 bits (342), Expect = 9e-33, Method: Compositional matrix adjust. Identities = 86/222 (38%), Positives = 129/222 (58%), Gaps = 12/222 (5%) Query: 19 RAYLAEFISTLLFVFAGVGSAIAY-----AKLTSDAALDTPGLVAIAVCHGFALFVAVAI 73 RA +AEF++ +LF+F +GSA+ + + T+ A D V +++ G ++ Sbjct: 12 RAVVAEFLAMILFIFISIGSALGFHYPIKSNQTTGAVQDN---VKVSLAFGLSIATLAQS 68 Query: 74 GANISGGHVNPAVTFGLAVGGQITVITGVFYWIAQLLGSTAACFLLKYVTGGL---AVPT 130 +ISG H+NPAVT GL + QI+V+ + Y IAQ +G+ A +L +T L ++ Sbjct: 69 VGHISGAHLNPAVTLGLLLSCQISVLRAIMYIIAQCVGAIVATAILSGITSSLPDNSLGL 128 Query: 131 HSVAAGLGSIEGVVMEIIITFALVYTVYATAADPKKGSLGTIAPLAIGLIVGANILAAGP 190 +++A G+ S +G+ +EII T LV V AT D ++ LG PLAIG V L A Sbjct: 129 NALAPGVNSGQGLGIEIIGTLQLVLCVLATT-DRRRRDLGGSGPLAIGFSVALGHLLAID 187 Query: 191 FSGGSMNPARSFGPAVAAGDFSGHWVYWVGPLIGGGLAGLIY 232 ++G +NPARSFG +V +F HW++WVGP IG LA LIY Sbjct: 188 YTGCGINPARSFGSSVITHNFQDHWIFWVGPFIGAALAVLIY 229 >4NEF-A nrPDB Length = 242 Score = 136 bits (342), Expect = 1e-32, Method: Compositional matrix adjust. Identities = 91/230 (39%), Positives = 128/230 (55%), Gaps = 19/230 (8%) Query: 14 SLASLRAYLAEFISTLLFVFAGVGSAIAYAKLTSDAALDTPGLVAIAVCHGFALFVAVAI 73 S+A RA AEF++TLLFVF G+GSA+ + + P ++ IA+ G + V Sbjct: 6 SIAFSRAVFAEFLATLLFVFFGLGSALNWPQ-------ALPSVLQIAMAFGLGIGTLVQA 58 Query: 74 GANISGGHVNPAVTFGLAVGGQITVITGVFYWIAQLLGSTAACFLLKYVT-----GGLAV 128 +ISG H+NPAVT VG ++V+ FY AQLLG+ A LL +T G LAV Sbjct: 59 LGHISGAHINPAVTVACLVGCHVSVLRAAFYVAAQLLGAVAGAALLHEITPADIRGDLAV 118 Query: 129 P--THSVAAGLGSIEGVVMEIIITFALVYTVYATAADPKKGSLGTIAPLAIGLIVGANIL 186 ++S AG + V +E+ +T LV ++A+ + + + GT A L+IG V L Sbjct: 119 NALSNSTTAG----QAVTVELFLTLQLVLCIFASTDERRGENPGTPA-LSIGFSVALGHL 173 Query: 187 AAGPFSGGSMNPARSFGPAVAAGDFSGHWVYWVGPLIGGGLAGLIYGNVF 236 ++G SMNPARS PAV G F HWV+W+GPL+G L L+Y V Sbjct: 174 LGIHYTGCSMNPARSLAPAVVTGKFDDHWVFWIGPLVGAILGSLLYNYVL 223 >3D9S-A nrPDB Length = 266 Score = 131 bits (329), Expect = 3e-31, Method: Compositional matrix adjust. Identities = 96/232 (41%), Positives = 140/232 (60%), Gaps = 18/232 (7%) Query: 8 SFDDSFSLASLRAYLAEFISTLLFVFAGVGSAIAYAKLTSDAALDTPGLVAIAVCHGFAL 67 S + S+A L+A AEF++TL+FVF G+GSA+ + +AL P ++ IA+ G A+ Sbjct: 2 SKKEVCSVAFLKAVFAEFLATLIFVFFGLGSALKW-----PSAL--PTILQIALAFGLAI 54 Query: 68 -FVAVAIGANISGGHVNPAVTFGLAVGGQITVITGVFYWIAQLLGSTAACFLLKYV---- 122 +A A+G +SGGH+NPA+T L VG QI+++ FY AQL+G+ A +L V Sbjct: 55 GTLAQALGP-VSGGHINPAITLALLVGNQISLLRAFFYVAAQLVGAIAGAGILYGVAPLN 113 Query: 123 -TGGLAVPTHSVAAGLGSIEGVVMEIIITFALVYTVYATAADPKKGSLGTIAPLAIGLIV 181 G LAV + G + +V+E+I+TF L ++A+ + +G+ A L+IGL V Sbjct: 114 ARGNLAVNALNNNTTQG--QAMVVELILTFQLALCIFASTDSRRTSPVGSPA-LSIGLSV 170 Query: 182 GANILAAGPFSGGSMNPARSFGPAVAAGDFS-GHWVYWVGPLIGGGLAGLIY 232 L F+G SMNPARSFGPAV FS HWV+WVGP++G LA ++Y Sbjct: 171 TLGHLVGIYFTGCSMNPARSFGPAVVMNRFSPAHWVFWVGPIVGAVLAAILY 222 >3CLL-A nrPDB Length = 300 Score = 125 bits (313), Expect = 2e-29, Method: Compositional matrix adjust. Identities = 90/221 (40%), Positives = 124/221 (56%), Gaps = 14/221 (6%) Query: 19 RAYLAEFISTLLFVFAGVGSAIAYAKLTSDAALDTPGLVAIAVCHGFALFVAVAIGANIS 78 RA +AEFI+TLLF++ V + I ++K T + GL+ IA G +FV V A IS Sbjct: 58 RAAIAEFIATLLFLYITVATVIGHSKET--VVCGSVGLLGIAWAFGGMIFVLVYCTAGIS 115 Query: 79 GGHVNPAVTFGLAVGGQITVITGVFYWIAQLLGSTAACFLLKYVTGGLAVP----THSVA 134 GGH+NPAVTFGL + ++ ++ + Y IAQ LG+ L+K G +SVA Sbjct: 116 GGHINPAVTFGLFLARKVELLRALVYMIAQCLGAICGVGLVKAFMKGPYNQFGGGANSVA 175 Query: 135 AGLGSIEGVVMEIIITFALVYTVYATAADPKKGSLGT----IAPLAIGLIVGANILAAGP 190 G + EII TF LVYTV+ +A DPK+ + + +APL IG V LA P Sbjct: 176 LGYNKGTALGAEIIGTFVLVYTVF-SATDPKRSARDSHVPILAPLPIGFAVFMVHLATIP 234 Query: 191 FSGGSMNPARSFGPAV---AAGDFSGHWVYWVGPLIGGGLA 228 +G +NPARSFG AV + + W++WVGP IG +A Sbjct: 235 ITGTGINPARSFGAAVIFNSNKVWDDQWIFWVGPFIGAAVA 275 >2W1P-A nrPDB Length = 279 Score = 91.3 bits (225), Expect = 4e-19, Method: Compositional matrix adjust. Identities = 68/212 (32%), Positives = 103/212 (48%), Gaps = 5/212 (2%) Query: 24 EFISTLLFVFAG--VGSAIAYAKLTSDAALDTPGLVAIAVCHGFALFVAVAIGANISGGH 81 EF+ T LF+++ + A T D + L+ I+ GF + V V I +SGG+ Sbjct: 51 EFVGTFLFLWSAFVIAQIANQAPETPDGGSNPAQLIMISFGFGFGVMVGVFITYRVSGGN 110 Query: 82 VNPAVTFGLAVGGQITVITGVFYWIAQLLGSTAACFLLKYVTGGLAVPTHSVAAGLGSIE 141 +NPAVT L + I G+ Q++ AA +T G +++ G Sbjct: 111 LNPAVTLALVLARAIPPFRGILMAFTQIVAGMAAAGAASAMTPGEIAFANALGGGASRTR 170 Query: 142 GVVMEIIITFALVYTVYATAADPKKGSLGTIAPLAIGLIVGANILAAGPFSGGSMNPARS 201 G+ +E T L TV A + + + AP IG+ + L ++G +NPARS Sbjct: 171 GLFLEAFGTAILCLTVLMLAVEKHRATW--FAPFVIGIALLIAHLICIYYTGAGLNPARS 228 Query: 202 FGPAVAAGDFSG-HWVYWVGPLIGGGLAGLIY 232 FGPAVAA F HW+YW+GP++G LA I+ Sbjct: 229 FGPAVAARSFPNYHWIYWLGPILGAFLAYSIW 260 >2EVU-A nrPDB Length = 246 Score = 87.8 bits (216), Expect = 4e-18, Method: Compositional matrix adjust. Identities = 82/239 (34%), Positives = 112/239 (46%), Gaps = 29/239 (12%) Query: 19 RAYLAEFISTLLFVFAGVGSAIAYAKLTSDAALDTP------------GLVAIAVCHGFA 66 + +AEFI T + VF G GSA + S P VAI + GFA Sbjct: 6 KRCIAEFIGTFILVFFGAGSAAVTLMIASGGTSPNPFNIGIGLLGGLGDWVAIGLAFGFA 65 Query: 67 LFVAVAIGANISGGHVNPAVTFGLAVGGQITVITGVFYWIAQLLGSTAACFLLKYVTGGL 126 + ++ NISG H+NPAVT GL + V Y IAQLLG+ F+ G Sbjct: 66 IAASIYALGNISGCHINPAVTIGLWSVKKFPGREVVPYIIAQLLGAAFGSFIFLQCAGIG 125 Query: 127 AVPTHSVAA-----GLGSIEGVVMEIIITFALVYTVYATAADPK--KGSLGTIAPLAIGL 179 A + A G+ + ++ E++ TF L+ T+ A D + KG G I IGL Sbjct: 126 AATVGGLGATAPFPGISYWQAMLAEVVGTFLLMITIMGIAVDERAPKGFAGII----IGL 181 Query: 180 IVGANILAAGPFSGGSMNPARSFGPAVAAGDFSGH--WVYW----VGPLIGGGLAGLIY 232 V I G SG S+NPAR+FGP + F+G W Y+ +GP++G LA L Y Sbjct: 182 TVAGIITTLGNISGSSLNPARTFGPYLNDMIFAGTDLWNYYSIYVIGPIVGAVLAALTY 240 >3LLQ-A nrPDB Length = 256 Score = 68.6 bits (166), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 77/229 (33%), Positives = 111/229 (48%), Gaps = 25/229 (10%) Query: 19 RAYLAEFISTLLFVFAGVGSAIAYAKLTSDAALDTPGLVAIAVCHGFA-LFVAVAIGANI 77 R LAEF T VF G GSA+ A G +A+ G L +A A+G I Sbjct: 31 RKLLAEFFGTFWLVFGGCGSAVFAAAFPELGI----GFTGVALAFGLTVLTMAYAVG-GI 85 Query: 78 SGGHVNPAVTFGLAVGGQITVITGVFYWIAQLLGSTAACFLLKYVTGGLA---------- 127 SGGH NPAV+ GL V G+ + V Y IAQ+ G+ A L + G A Sbjct: 86 SGGHFNPAVSVGLTVAGRFPASSLVPYVIAQVAGAIVAAAALYVIATGKAGIDLGGFASN 145 Query: 128 -VPTHSVAAGLGSIEGVVMEIIIT-FALVYTVYATAADPKKGSLGTIAPLAIGLIVGANI 185 HS G + +++EII+T F L+ + +T G AP+AIGL + Sbjct: 146 GYGEHS-PGGYSLVSALLIEIILTAFFLIVILGSTHGRVPAG----FAPIAIGLALTLIH 200 Query: 186 LAAGPFSGGSMNPARSFGPAVAAGDFSGH--WVYWVGPLIGGGLAGLIY 232 L + P + S+NPARS G A+ G ++ W++W+ P++GG +I+ Sbjct: 201 LISIPVTNTSVNPARSTGQALFVGGWALQQLWLFWLAPIVGGAAGAVIW 249 >3NE2-A nrPDB Length = 246 Score = 65.9 bits (159), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 72/240 (30%), Positives = 106/240 (44%), Gaps = 32/240 (13%) Query: 19 RAYLAEFISTLLFVFAGVGSAIAYAKLTSDAALDTPGLVA------------IAVCHGFA 66 + + AE + T + VF G G+A+ + + A D P A+ FA Sbjct: 7 KRFTAEVVGTFILVFFGPGAAVITLMIANGA--DKPNEFNIGIGALGGLGDWFAIGMAFA 64 Query: 67 LFVAVAIGA--NISGGHVNPAVTFGLAVGGQITVITGVFYWIAQLLGSTAACFLLKYVTG 124 L +A I + ISG H+NPAVT L G+ V Y +AQ +G+ L G Sbjct: 65 LAIAAVIYSLGRISGAHINPAVTIALWSIGRFPGREVVPYIVAQFIGAALGSLLFLACVG 124 Query: 125 GLAVPTHSVAA-----GLGSIEGVVMEIIITFALVYTVYATAADPKKGSLGTIAPLAIGL 179 A + A G+G + ++ E I TF L+ + A D + A L IGL Sbjct: 125 PAAATVGGLGATAPFPGIGYGQAILTEAIGTFLLMLVIMGVAVDERAPP--GFAGLVIGL 182 Query: 180 IVGANILAAGPFSGGSMNPARSFGPAVAAGD-------FSGHWVYWVGPLIGGGLAGLIY 232 VG I G +G S+NPAR+FGP + GD + +Y +GP++G A +Y Sbjct: 183 TVGGIITTIGNITGSSLNPARTFGPYL--GDSLMGINLWQYFPIYVIGPIVGAVAAAWLY 240 >1LDI-A nrPDB Length = 281 Score = 62.4 bits (150), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 62/208 (29%), Positives = 93/208 (44%), Gaps = 26/208 (12%) Query: 22 LAEFISTLLFVFAGVGSAIAYAKLTSDAALDTPGLVAIAVCHGFALFVAVAIGANISGGH 81 +AEF+ T L +F GVG A A + G I+V G + +A+ + A +SG H Sbjct: 12 IAEFLGTGLLIFFGVGCVAAL-----KVAGASFGQWEISVIWGLGVAMAIYLTAGVSGAH 66 Query: 82 VNPAVTFGL---AVGGQITVITGVFYWIAQLLGSTAACFLLKYVTGGLAVPTHSVAAG-- 136 +NPAVT L A + VI + +A + A + L Y TH + G Sbjct: 67 LNPAVTIALWLFACFDKRKVIPFIVSQVAGAFCAAALVYGLYYNLFFDFEQTHHIVRGSV 126 Query: 137 ----------------LGSIEGVVMEIIITFALVYTVYATAADPKKGSLGTIAPLAIGLI 180 + ++ +E++IT L+ + A D G +APL IGL+ Sbjct: 127 ESVDLAGTFSTYPNPHINFVQAFAVEMVITAILMGLILALTDDGNGVPRGPLAPLLIGLL 186 Query: 181 VGANILAAGPFSGGSMNPARSFGPAVAA 208 + + GP +G +MNPAR FGP V A Sbjct: 187 IAVIGASMGPLTGFAMNPARDFGPKVFA 214 >2O9F-A nrPDB Length = 234 Score = 58.9 bits (141), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 68/217 (31%), Positives = 99/217 (45%), Gaps = 25/217 (11%) Query: 18 LRAYLAEFISTLLFVFAGVGSAIAYAKLTSDAALDTPGLVAIAVCHGFA-LFVAVAIGAN 76 R AE T VF G GSA+ A G +A+ G L +A A+G + Sbjct: 5 FRKLAAESFGTFWLVFGGSGSAVLAAGFPELGI----GFAGVALAFGLTVLTMAFAVG-H 59 Query: 77 ISGGHVNPAVTFGLAVGGQITVITGVFYWIAQLLGSTAACFLLKYVTGGLAVPTHSVAAG 136 ISGGH NPAVT GL GG+ V Y IAQ++G A LL + G + A+G Sbjct: 60 ISGGHFNPAVTIGLWAGGRFPAKEVVGYVIAQVVGGIVAAALLYLIASG-KTGFDAAASG 118 Query: 137 LGS-------------IEGVVMEIIITFALVYTVYATAADPKKGSLGTIAPLAIGLIVGA 183 S + +V+E++++ + ++ A D K + AP+AIGL Sbjct: 119 FASNGYGEHSPGGYSMLSALVVELVLSAGFLLVIHG-ATD--KFAPAGFAPIAIGLACTL 175 Query: 184 NILAAGPFSGGSMNPARSFGPAVAAGDFSGH--WVYW 218 L + P + S+NPARS A+ G ++ W +W Sbjct: 176 IHLISIPVTNTSVNPARSTAVAIFQGGWALEQLWFFW 212 >6F7H-A nrPDB Length = 301 Score = 51.6 bits (122), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 60/236 (25%), Positives = 103/236 (43%), Gaps = 35/236 (14%) Query: 19 RAYLAEFISTLLFVFAGVGSAIAYAKLTSDAALDTPGLVAIAVCHGFALFVAVAIGANIS 78 R LAEF+ + + G A+A A + + + + + A+ +A+ +G N+S Sbjct: 22 RQCLAEFLGVFVLMLLTQG-AVAQAVTSGETKGN---FFTMFLAGSLAVTIAIYVGGNVS 77 Query: 79 GGHVNPAVTFGLAVGGQITVITGVFYWIAQLL------GSTAACF---LLKYVTGGLAV- 128 G H+NPA + + + G++ + Y + QLL G+T + L Y G L V Sbjct: 78 GAHLNPAFSLAMCIVGRLPWVKLPIYILVQLLSAFCASGATYVLYHDALQNYTGGNLTVT 137 Query: 129 -PTHSV-------AAGLGSIEGVVMEIIITFALVYTVYATAADPKKGSLGTIAPLAIGLI 180 P + A L G + +++ T L+ + A KG + P+ +G++ Sbjct: 138 GPKETASIFATYPAPYLSLNNGFLDQVLGTGMLIVGLLAILDRRNKGVPAGLEPVVVGML 197 Query: 181 VGANILAAGPFSGGSMNPARSFGPAV------------AAGDFSGHWVYWVGPLIG 224 + A L+ G G +NPAR GP + +AG+ WV V PL+G Sbjct: 198 ILALGLSMGANCGIPLNPARDLGPRLFTYVAGWGPEVFSAGN-GWWWVPVVAPLVG 252 >3C02-A nrPDB Length = 258 Score = 42.4 bits (98), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 59/248 (23%), Positives = 98/248 (39%), Gaps = 36/248 (14%) Query: 13 FSLASLRAYLAEFISTLLFVFAGVGSAIAYAKLTSDAALDTPGL----VAIAVCHGFALF 68 F + +R ++ EF+ T + +F G G+ A T GL + + G A+F Sbjct: 5 FYKSYVREFIGEFLGTFVLMFLGEGAT---------ANFHTTGLSGDWYKLCLGWGLAVF 55 Query: 69 VAVAIGANISGGHVNPAVTFGLAVGGQITVITGVFYWIAQLLGS---TAACFLLKY-VTG 124 + + A +SG H+N AV+ GL+ + + Y+ AQLLG+ T+ + L + Sbjct: 56 FGILVSAKLSGAHLNLAVSIGLSSINKFDLKKIPVYFFAQLLGAFVGTSTVYGLYHGFIS 115 Query: 125 GLAVPTHSVAAGLG---SIEGVVMEIIITFALVYTVYATAADPKKGSLGTIAPLAIGLIV 181 +P + S+ G +I ++ V D + G L + +V Sbjct: 116 NSKIPQFAWETSRNPSISLTGAFFNELILTGILLLVILVVVD--ENICGKFHILKLSSVV 173 Query: 182 GANILAAGPFSGGS----MNPARS----------FGPAVAAGDFSGHWVYWVGPLIGGGL 227 G IL G GG+ +NP+R +G D WV V P +G + Sbjct: 174 GLIILCIGITFGGNTGFALNPSRDLGSRFLSLIAYGKDTFTKDNFYFWVPLVAPCVGSVV 233 Query: 228 AGLIYGNV 235 Y V Sbjct: 234 FCQFYDKV 241 >5D68-A nrPDB Length = 486 Score = 32.7 bits (73), Expect = 0.15, Method: Compositional matrix adjust. Identities = 21/69 (30%), Positives = 31/69 (44%), Gaps = 7/69 (10%) Query: 69 VAVAIGANISGGHVNPAVTFGLAVGGQITVITGVFYWIAQLLGSTAACFLLKYVTGGLAV 128 + V +G NI G H+ T L I++ G F W LG T CF + + ++ Sbjct: 406 IPVYVGVNIKGLHLLNMETKALL----ISLKYGCFMW---QLGDTDTCFQIHSMENKMSF 458 Query: 129 PTHSVAAGL 137 H+ AGL Sbjct: 459 IVHTKQAGL 467 >4HDO-A nrPDB Length = 322 Score = 32.7 bits (73), Expect = 0.16, Method: Compositional matrix adjust. Identities = 21/69 (30%), Positives = 31/69 (44%), Gaps = 7/69 (10%) Query: 69 VAVAIGANISGGHVNPAVTFGLAVGGQITVITGVFYWIAQLLGSTAACFLLKYVTGGLAV 128 + V +G NI G H+ T L I++ G F W LG T CF + + ++ Sbjct: 242 IPVYVGVNIKGLHLLNMETKALL----ISLKYGCFMW---QLGDTDTCFQIHSMENKMSF 294 Query: 129 PTHSVAAGL 137 H+ AGL Sbjct: 295 IVHTKQAGL 303 >4ZB4-A nrPDB Length = 360 Score = 29.3 bits (64), Expect = 1.6, Method: Compositional matrix adjust. Identities = 11/30 (36%), Positives = 16/30 (53%) Query: 104 YWIAQLLGSTAACFLLKYVTGGLAVPTHSV 133 YW+ T CF L+ G LA PT+++ Sbjct: 244 YWMVVECDQTVVCFDLRKDVGTLAYPTYTI 273 >5LJ5-t nrPDB Length = 503 Score = 29.3 bits (64), Expect = 1.6, Method: Compositional matrix adjust. Identities = 11/30 (36%), Positives = 16/30 (53%) Query: 104 YWIAQLLGSTAACFLLKYVTGGLAVPTHSV 133 YW+ T CF L+ G LA PT+++ Sbjct: 387 YWMVVECDQTVVCFDLRKDVGTLAYPTYTI 416 >3TDO-A nrPDB Length = 268 Score = 27.7 bits (60), Expect = 5.0, Method: Compositional matrix adjust. Identities = 17/44 (38%), Positives = 23/44 (52%), Gaps = 2/44 (4%) Query: 191 FSGGSM-NPARSFGPAVAAGDFSGHWVY-WVGPLIGGGLAGLIY 232 F+G +M A V+ D S W Y WVG LIG + G+I+ Sbjct: 86 FTGNNMVMSAGMLNKGVSIKDTSKIWAYSWVGNLIGALVLGIIF 129 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 3IYZ-A nrPDB 266 5e-72 2ZZ9-A nrPDB 264 2e-71 5I32-A nrPDB 254 3e-68 1IH5-A nrPDB 244 3e-65 1J4N-A nrPDB 239 1e-63 4OJ2-X nrPDB 227 3e-60 3GD8-A nrPDB 222 1e-58 3D9S-A nrPDB 215 2e-56 1YMG-A nrPDB 212 1e-55 4NEF-A nrPDB 211 2e-55 3CLL-A nrPDB 195 2e-50 3M9I-A nrPDB 195 2e-50 2W1P-A nrPDB 182 1e-46 2EVU-A nrPDB 169 2e-42 3C02-A nrPDB 162 1e-40 3NE2-A nrPDB 162 1e-40 1LDI-A nrPDB 159 9e-40 6F7H-A nrPDB 157 3e-39 3LLQ-A nrPDB 147 4e-36 2O9F-A nrPDB 142 1e-34 Sequences not found previously or not previously below threshold: 4AGS-A nrPDB 30 1.4 6BH8-A nrPDB 27 7.8 3NWO-A nrPDB 27 9.9 CONVERGED! >3IYZ-A nrPDB Length = 340 Score = 266 bits (681), Expect = 5e-72, Method: Composition-based stats. Identities = 93/237 (39%), Positives = 136/237 (57%), Gaps = 7/237 (2%) Query: 8 SFDDSFSLASLRAYLAEFISTLLFVFAGVGSAIAYAKLTSDAALDTPGLVAIAVCHGFAL 67 +F ++ A +A AEF++ L+FV VGS I + + +D +V I++C G ++ Sbjct: 42 AFKGVWTQAFWKAVTAEFLAMLIFVLLSVGSTINWGGSENPLPVD---MVLISLCFGLSI 98 Query: 68 FVAVAIGANISGGHVNPAVTFGLAVGGQITVITGVFYWIAQLLGSTAACFLLKYVTGGLA 127 V +ISGGH+NPAVT + +I++ VFY AQ LG+ +L VT Sbjct: 99 ATMVQCFGHISGGHINPAVTVAMVCTRKISIAKSVFYITAQCLGAIIGAGILYLVTPPSV 158 Query: 128 VP---THSVAAGLGSIEGVVMEIIITFALVYTVYATAADPKKGSLGTIAPLAIGLIVGAN 184 V +V L + G+++E+IITF LV+T++A+ D + G++A LAIG V Sbjct: 159 VGGLGVTTVHGNLTAGHGLLVELIITFQLVFTIFASCDDKRTDVTGSVA-LAIGFSVAIG 217 Query: 185 ILAAGPFSGGSMNPARSFGPAVAAGDFSGHWVYWVGPLIGGGLAGLIYGNVFMGSSE 241 L A ++G SMNPARSFGPAV G++ HW+YWVGP+IG LAG +Y VF E Sbjct: 218 HLFAINYTGASMNPARSFGPAVIMGNWENHWIYWVGPIIGAVLAGALYEYVFCPDVE 274 >2ZZ9-A nrPDB Length = 301 Score = 264 bits (676), Expect = 2e-71, Method: Composition-based stats. Identities = 93/237 (39%), Positives = 136/237 (57%), Gaps = 7/237 (2%) Query: 8 SFDDSFSLASLRAYLAEFISTLLFVFAGVGSAIAYAKLTSDAALDTPGLVAIAVCHGFAL 67 +F ++ A +A AEF++ L+FV VGS I + + +D +V I++C G ++ Sbjct: 3 AFKGVWTQAFWKAVTAEFLAMLIFVLLSVGSTINWGGSENPLPVD---MVLISLCFGLSI 59 Query: 68 FVAVAIGANISGGHVNPAVTFGLAVGGQITVITGVFYWIAQLLGSTAACFLLKYVTGGLA 127 V +ISGGH+NPAVT + +I++ VFY AQ LG+ +L VT Sbjct: 60 ATMVQCFGHISGGHINPAVTVAMVCTRKISIAKSVFYITAQCLGAIIGAGILYLVTPPSV 119 Query: 128 VP---THSVAAGLGSIEGVVMEIIITFALVYTVYATAADPKKGSLGTIAPLAIGLIVGAN 184 V +V L + G+++E+IITF LV+T++A+ D + G++A LAIG V Sbjct: 120 VGGLGVTTVHGNLTAGHGLLVELIITFQLVFTIFASCDDKRTDVTGSVA-LAIGFSVAIG 178 Query: 185 ILAAGPFSGGSMNPARSFGPAVAAGDFSGHWVYWVGPLIGGGLAGLIYGNVFMGSSE 241 L A ++G SMNPARSFGPAV G++ HW+YWVGP+IG LAG +Y VF E Sbjct: 179 HLFAINYTGASMNPARSFGPAVIMGNWENHWIYWVGPIIGAVLAGALYEYVFCPDVE 235 >5I32-A nrPDB Length = 275 Score = 254 bits (648), Expect = 3e-68, Method: Composition-based stats. Identities = 249/249 (100%), Positives = 249/249 (100%) Query: 2 AGVAFGSFDDSFSLASLRAYLAEFISTLLFVFAGVGSAIAYAKLTSDAALDTPGLVAIAV 61 AGVAFGSFDDSFSLASLRAYLAEFISTLLFVFAGVGSAIAYAKLTSDAALDTPGLVAIAV Sbjct: 27 AGVAFGSFDDSFSLASLRAYLAEFISTLLFVFAGVGSAIAYAKLTSDAALDTPGLVAIAV 86 Query: 62 CHGFALFVAVAIGANISGGHVNPAVTFGLAVGGQITVITGVFYWIAQLLGSTAACFLLKY 121 CHGFALFVAVAIGANISGGHVNPAVTFGLAVGGQITVITGVFYWIAQLLGSTAACFLLKY Sbjct: 87 CHGFALFVAVAIGANISGGHVNPAVTFGLAVGGQITVITGVFYWIAQLLGSTAACFLLKY 146 Query: 122 VTGGLAVPTHSVAAGLGSIEGVVMEIIITFALVYTVYATAADPKKGSLGTIAPLAIGLIV 181 VTGGLAVPTHSVAAGLGSIEGVVMEIIITFALVYTVYATAADPKKGSLGTIAPLAIGLIV Sbjct: 147 VTGGLAVPTHSVAAGLGSIEGVVMEIIITFALVYTVYATAADPKKGSLGTIAPLAIGLIV 206 Query: 182 GANILAAGPFSGGSMNPARSFGPAVAAGDFSGHWVYWVGPLIGGGLAGLIYGNVFMGSSE 241 GANILAAGPFSGGSMNPARSFGPAVAAGDFSGHWVYWVGPLIGGGLAGLIYGNVFMGSSE Sbjct: 207 GANILAAGPFSGGSMNPARSFGPAVAAGDFSGHWVYWVGPLIGGGLAGLIYGNVFMGSSE 266 Query: 242 HVPLASADF 250 HVPLASADF Sbjct: 267 HVPLASADF 275 >1IH5-A nrPDB Length = 269 Score = 244 bits (623), Expect = 3e-65, Method: Composition-based stats. Identities = 89/227 (39%), Positives = 128/227 (56%), Gaps = 4/227 (1%) Query: 17 SLRAYLAEFISTLLFVFAGVGSAIAYAKLTSDAALDTPGLVAIAVCHGFALFVAVAIGAN 76 RA +AEF++T LFVF +GSA+ + + V +++ G ++ + Sbjct: 10 FWRAVVAEFLATTLFVFISIGSALGFKYPVGNNQTAVQDNVKVSLAFGLSIATLAQSVGH 69 Query: 77 ISGGHVNPAVTFGLAVGGQITVITGVFYWIAQLLGSTAACFLLKYVTGGL---AVPTHSV 133 ISG H+NPAVT GL + QI++ + Y IAQ +G+ A +L +T L ++ + + Sbjct: 70 ISGAHLNPAVTLGLLLSCQISIFRALMYIIAQCVGAIVATAILSGITSSLTGNSLGRNDL 129 Query: 134 AAGLGSIEGVVMEIIITFALVYTVYATAADPKKGSLGTIAPLAIGLIVGANILAAGPFSG 193 A G+ S +G+ +EII T LV V AT ++ LG APLAIGL V L A ++G Sbjct: 130 ADGVNSGQGLGIEIIGTLQLVLCVLATTDRRRRD-LGGSAPLAIGLSVALGHLLAIDYTG 188 Query: 194 GSMNPARSFGPAVAAGDFSGHWVYWVGPLIGGGLAGLIYGNVFMGSS 240 +NPARSFG AV +FS HW++WVGP IGG LA LIY + S Sbjct: 189 CGINPARSFGSAVITHNFSNHWIFWVGPFIGGALAVLIYDFILAPRS 235 >1J4N-A nrPDB Length = 271 Score = 239 bits (609), Expect = 1e-63, Method: Composition-based stats. Identities = 84/229 (36%), Positives = 127/229 (55%), Gaps = 6/229 (2%) Query: 17 SLRAYLAEFISTLLFVFAGVGSAIA--YAKLTSDAALDTPGLVAIAVCHGFALFVAVAIG 74 RA +AEF++ +LF+F +GSA+ Y ++ V +++ G ++ Sbjct: 10 FWRAVVAEFLAMILFIFISIGSALGFHYPIKSNQTTGAVQDNVKVSLAFGLSIATLAQSV 69 Query: 75 ANISGGHVNPAVTFGLAVGGQITVITGVFYWIAQLLGSTAACFLLKYVTGGL---AVPTH 131 +ISG H+NPAVT GL + QI+V+ + Y IAQ +G+ A +L +T L ++ + Sbjct: 70 GHISGAHLNPAVTLGLLLSCQISVLRAIMYIIAQCVGAIVATAILSGITSSLPDNSLGLN 129 Query: 132 SVAAGLGSIEGVVMEIIITFALVYTVYATAADPKKGSLGTIAPLAIGLIVGANILAAGPF 191 ++A G+ S +G+ +EII T LV V AT ++ LG PLAIG V L A + Sbjct: 130 ALAPGVNSGQGLGIEIIGTLQLVLCVLATTDRRRRD-LGGSGPLAIGFSVALGHLLAIDY 188 Query: 192 SGGSMNPARSFGPAVAAGDFSGHWVYWVGPLIGGGLAGLIYGNVFMGSS 240 +G +NPARSFG +V +F HW++WVGP IG LA LIY + S Sbjct: 189 TGCGINPARSFGSSVITHNFQDHWIFWVGPFIGAALAVLIYDFILAPRS 237 >4OJ2-X nrPDB Length = 274 Score = 227 bits (579), Expect = 3e-60, Method: Composition-based stats. Identities = 84/231 (36%), Positives = 125/231 (54%), Gaps = 11/231 (4%) Query: 14 SLASLRAYLAEFISTLLFVFAGVGSAIAYAKLTSDAALDTPGLVAIAVCHGFALFVAVAI 73 S+A RA AEF++TLLFVF G+GSA+ + P ++ IA+ G + V Sbjct: 9 SIAFSRAVFAEFLATLLFVFFGLGSALNW-------PQALPSVLQIAMAFGLGIGTLVQA 61 Query: 74 GANISGGHVNPAVTFGLAVGGQITVITGVFYWIAQLLGSTAACFLLKYVTGGLAVP---T 130 +ISG H+NPAVT VG ++V+ FY AQLLG+ A LL +T Sbjct: 62 LGHISGAHINPAVTVACLVGCHVSVLRAAFYVAAQLLGAVAGAALLHEITPADIRGDLAV 121 Query: 131 HSVAAGLGSIEGVVMEIIITFALVYTVYATAADPKKGSLGTIAPLAIGLIVGANILAAGP 190 ++++ + + V +E+ +T LV ++A+ + + + GT A L+IG V L Sbjct: 122 NALSNSTTAGQAVTVELFLTLQLVLCIFASTDERRGENPGTPA-LSIGFSVALGHLLGIH 180 Query: 191 FSGGSMNPARSFGPAVAAGDFSGHWVYWVGPLIGGGLAGLIYGNVFMGSSE 241 ++G SMNPARS PAV G F HWV+W+GPL+G L L+Y V ++ Sbjct: 181 YTGCSMNPARSLAPAVVTGKFDDHWVFWIGPLVGAILGSLLYNYVLFPPAK 231 >3GD8-A nrPDB Length = 223 Score = 222 bits (566), Expect = 1e-58, Method: Composition-based stats. Identities = 90/227 (39%), Positives = 128/227 (56%), Gaps = 7/227 (3%) Query: 15 LASLRAYLAEFISTLLFVFAGVGSAIAYAKLTSDAALDTPGLVAIAVCHGFALFVAVAIG 74 A +A AEF++ L+FV +GS I + +D +V I++C G ++ V Sbjct: 1 QAFWKAVTAEFLAMLIFVLLSLGSTINWGGTEKPLPVD---MVLISLCFGLSIATMVQCF 57 Query: 75 ANISGGHVNPAVTFGLAVGGQITVITGVFYWIAQLLGSTAACFLLKYVTGGLAVPTHSV- 133 +ISGGH+NPAVT + +I++ VFY AQ LG+ +L VT V V Sbjct: 58 GHISGGHINPAVTVAMVCTRKISIAKSVFYIAAQCLGAIIGAGILYLVTPPSVVGGLGVT 117 Query: 134 --AAGLGSIEGVVMEIIITFALVYTVYATAADPKKGSLGTIAPLAIGLIVGANILAAGPF 191 L + G+++E+IITF LV+T++A+ + G+IA LAIG V L A + Sbjct: 118 MVHGNLTAGHGLLVELIITFQLVFTIFASCDSKRTDVTGSIA-LAIGFSVAIGHLFAINY 176 Query: 192 SGGSMNPARSFGPAVAAGDFSGHWVYWVGPLIGGGLAGLIYGNVFMG 238 +G SMNPARSFGPAV G++ HW+YWVGP+IG LAG +Y VF Sbjct: 177 TGASMNPARSFGPAVIMGNWENHWIYWVGPIIGAVLAGGLYEYVFCP 223 >3D9S-A nrPDB Length = 266 Score = 215 bits (547), Expect = 2e-56, Method: Composition-based stats. Identities = 89/237 (37%), Positives = 132/237 (55%), Gaps = 12/237 (5%) Query: 8 SFDDSFSLASLRAYLAEFISTLLFVFAGVGSAIAYAKLTSDAALDTPGLVAIAVCHGFAL 67 S + S+A L+A AEF++TL+FVF G+GSA+ + P ++ IA+ G A+ Sbjct: 2 SKKEVCSVAFLKAVFAEFLATLIFVFFGLGSALKW-------PSALPTILQIALAFGLAI 54 Query: 68 FVAVAIGANISGGHVNPAVTFGLAVGGQITVITGVFYWIAQLLGSTAACFLLKYVTGGLA 127 +SGGH+NPA+T L VG QI+++ FY AQL+G+ A +L V A Sbjct: 55 GTLAQALGPVSGGHINPAITLALLVGNQISLLRAFFYVAAQLVGAIAGAGILYGVAPLNA 114 Query: 128 VPTHSVAAGL---GSIEGVVMEIIITFALVYTVYATAADPKKGSLGTIAPLAIGLIVGAN 184 +V A + +V+E+I+TF L ++A+ + +G+ A L+IGL V Sbjct: 115 RGNLAVNALNNNTTQGQAMVVELILTFQLALCIFASTDSRRTSPVGSPA-LSIGLSVTLG 173 Query: 185 ILAAGPFSGGSMNPARSFGPAVAAGDF-SGHWVYWVGPLIGGGLAGLIYGNVFMGSS 240 L F+G SMNPARSFGPAV F HWV+WVGP++G LA ++Y + +S Sbjct: 174 HLVGIYFTGCSMNPARSFGPAVVMNRFSPAHWVFWVGPIVGAVLAAILYFYLLFPNS 230 >1YMG-A nrPDB Length = 263 Score = 212 bits (540), Expect = 1e-55, Method: Composition-based stats. Identities = 82/233 (35%), Positives = 129/233 (55%), Gaps = 11/233 (4%) Query: 14 SLASLRAYLAEFISTLLFVFAGVGSAIAYAKLTSDAALDTPGLVAIAVCHGFALFVAVAI 73 S + RA AEF ++L +VF G+G+++ +A ++ +A+ G AL V Sbjct: 6 SASFWRAICAEFFASLFYVFFGLGASLRWAP-------GPLHVLQVALAFGLALATLVQA 58 Query: 74 GANISGGHVNPAVTFGLAVGGQITVITGVFYWIAQLLGSTAACFLLKYVTGGLAVP---T 130 +ISG HVNPAVTF VG Q++++ + Y +AQLLG+ A +L VT Sbjct: 59 VGHISGAHVNPAVTFAFLVGSQMSLLRAICYMVAQLLGAVAGAAVLYSVTPPAVRGNLAL 118 Query: 131 HSVAAGLGSIEGVVMEIIITFALVYTVYATAADPKKGSLGTIAPLAIGLIVGANILAAGP 190 +++ G+ + ++EI +T V ++AT + + G LG++A LA+G + L Sbjct: 119 NTLHPGVSVGQATIVEIFLTLQFVLCIFATYDERRNGRLGSVA-LAVGFSLTLGHLFGMY 177 Query: 191 FSGGSMNPARSFGPAVAAGDFSGHWVYWVGPLIGGGLAGLIYGNVFMGSSEHV 243 ++G MNPARSF PA+ +F+ HWVYWVGP+IG GL L+Y + + V Sbjct: 178 YTGAGMNPARSFAPAILTRNFTNHWVYWVGPVIGAGLGSLLYDFLLFPRLKSV 230 >4NEF-A nrPDB Length = 242 Score = 211 bits (538), Expect = 2e-55, Method: Composition-based stats. Identities = 84/231 (36%), Positives = 125/231 (54%), Gaps = 11/231 (4%) Query: 14 SLASLRAYLAEFISTLLFVFAGVGSAIAYAKLTSDAALDTPGLVAIAVCHGFALFVAVAI 73 S+A RA AEF++TLLFVF G+GSA+ + P ++ IA+ G + V Sbjct: 6 SIAFSRAVFAEFLATLLFVFFGLGSALNW-------PQALPSVLQIAMAFGLGIGTLVQA 58 Query: 74 GANISGGHVNPAVTFGLAVGGQITVITGVFYWIAQLLGSTAACFLLKYVTGGLAVP---T 130 +ISG H+NPAVT VG ++V+ FY AQLLG+ A LL +T Sbjct: 59 LGHISGAHINPAVTVACLVGCHVSVLRAAFYVAAQLLGAVAGAALLHEITPADIRGDLAV 118 Query: 131 HSVAAGLGSIEGVVMEIIITFALVYTVYATAADPKKGSLGTIAPLAIGLIVGANILAAGP 190 ++++ + + V +E+ +T LV ++A+ + + + GT A L+IG V L Sbjct: 119 NALSNSTTAGQAVTVELFLTLQLVLCIFASTDERRGENPGTPA-LSIGFSVALGHLLGIH 177 Query: 191 FSGGSMNPARSFGPAVAAGDFSGHWVYWVGPLIGGGLAGLIYGNVFMGSSE 241 ++G SMNPARS PAV G F HWV+W+GPL+G L L+Y V ++ Sbjct: 178 YTGCSMNPARSLAPAVVTGKFDDHWVFWIGPLVGAILGSLLYNYVLFPPAK 228 >3CLL-A nrPDB Length = 300 Score = 195 bits (495), Expect = 2e-50, Method: Composition-based stats. Identities = 87/231 (37%), Positives = 121/231 (52%), Gaps = 12/231 (5%) Query: 16 ASLRAYLAEFISTLLFVFAGVGSAIAYAKLTSDAALDTPGLVAIAVCHGFALFVAVAIGA 75 + RA +AEFI+TLLF++ V + I ++K T + GL+ IA G +FV V A Sbjct: 55 SFWRAAIAEFIATLLFLYITVATVIGHSKET--VVCGSVGLLGIAWAFGGMIFVLVYCTA 112 Query: 76 NISGGHVNPAVTFGLAVGGQITVITGVFYWIAQLLGSTAACFLLKYVTGGLAV----PTH 131 ISGGH+NPAVTFGL + ++ ++ + Y IAQ LG+ L+K G + Sbjct: 113 GISGGHINPAVTFGLFLARKVELLRALVYMIAQCLGAICGVGLVKAFMKGPYNQFGGGAN 172 Query: 132 SVAAGLGSIEGVVMEIIITFALVYTVYATAADPKKGS---LGTIAPLAIGLIVGANILAA 188 SVA G + EII TF LVYTV++ + + +APL IG V LA Sbjct: 173 SVALGYNKGTALGAEIIGTFVLVYTVFSATDPKRSARDSHVPILAPLPIGFAVFMVHLAT 232 Query: 189 GPFSGGSMNPARSFGPAVA---AGDFSGHWVYWVGPLIGGGLAGLIYGNVF 236 P +G +NPARSFG AV + W++WVGP IG +A + V Sbjct: 233 IPITGTGINPARSFGAAVIFNSNKVWDDQWIFWVGPFIGAAVAAAYHQYVL 283 >3M9I-A nrPDB Length = 220 Score = 195 bits (495), Expect = 2e-50, Method: Composition-based stats. Identities = 81/226 (35%), Positives = 126/226 (55%), Gaps = 11/226 (4%) Query: 16 ASLRAYLAEFISTLLFVFAGVGSAIAYAKLTSDAALDTPGLVAIAVCHGFALFVAVAIGA 75 + RA AEF +TL +VF G+G+++ +A ++ +A+ G AL V Sbjct: 2 SFWRAIFAEFFATLFYVFFGLGASLRWAP-------GPLHVLQVALAFGLALATLVQAVG 54 Query: 76 NISGGHVNPAVTFGLAVGGQITVITGVFYWIAQLLGSTAACFLLKYVTGGLAVP---THS 132 +ISG HVNPAVTF VG Q++++ + Y +AQLLG+ A +L VT ++ Sbjct: 55 HISGAHVNPAVTFAFLVGSQMSLLRAICYVVAQLLGAVAGAAVLYSVTPPAVRGNLALNT 114 Query: 133 VAAGLGSIEGVVMEIIITFALVYTVYATAADPKKGSLGTIAPLAIGLIVGANILAAGPFS 192 + G+ + ++EI +T V ++AT + + G LG++A LA+G + L ++ Sbjct: 115 LHPGVSVGQATIVEIFLTLQFVLCIFATYDERRNGRLGSVA-LAVGFSLTLGHLFGMYYT 173 Query: 193 GGSMNPARSFGPAVAAGDFSGHWVYWVGPLIGGGLAGLIYGNVFMG 238 G MNPARSF PA+ +F+ HWVYWVGP+IG GL L+Y + Sbjct: 174 GAGMNPARSFAPAILTRNFTNHWVYWVGPVIGAGLGSLLYDFLLFP 219 >2W1P-A nrPDB Length = 279 Score = 182 bits (462), Expect = 1e-46, Method: Composition-based stats. Identities = 69/217 (31%), Positives = 103/217 (47%), Gaps = 5/217 (2%) Query: 20 AYLAEFISTLLFVF--AGVGSAIAYAKLTSDAALDTPGLVAIAVCHGFALFVAVAIGANI 77 A EF+ T LF++ + A T D + L+ I+ GF + V V I + Sbjct: 47 AMSGEFVGTFLFLWSAFVIAQIANQAPETPDGGSNPAQLIMISFGFGFGVMVGVFITYRV 106 Query: 78 SGGHVNPAVTFGLAVGGQITVITGVFYWIAQLLGSTAACFLLKYVTGGLAVPTHSVAAGL 137 SGG++NPAVT L + I G+ Q++ AA +T G +++ G Sbjct: 107 SGGNLNPAVTLALVLARAIPPFRGILMAFTQIVAGMAAAGAASAMTPGEIAFANALGGGA 166 Query: 138 GSIEGVVMEIIITFALVYTVYATAADPKKGSLGTIAPLAIGLIVGANILAAGPFSGGSMN 197 G+ +E T L TV A + + + AP IG+ + L ++G +N Sbjct: 167 SRTRGLFLEAFGTAILCLTVLMLAVEKHRATW--FAPFVIGIALLIAHLICIYYTGAGLN 224 Query: 198 PARSFGPAVAAGDFSG-HWVYWVGPLIGGGLAGLIYG 233 PARSFGPAVAA F HW+YW+GP++G LA I+ Sbjct: 225 PARSFGPAVAARSFPNYHWIYWLGPILGAFLAYSIWQ 261 >2EVU-A nrPDB Length = 246 Score = 169 bits (427), Expect = 2e-42, Method: Composition-based stats. Identities = 75/244 (30%), Positives = 112/244 (45%), Gaps = 25/244 (10%) Query: 15 LASLRAYLAEFISTLLFVFAGVGSAIAYAKLTSDAALDTP------------GLVAIAVC 62 ++ + +AEFI T + VF G GSA + S P VAI + Sbjct: 2 VSLTKRCIAEFIGTFILVFFGAGSAAVTLMIASGGTSPNPFNIGIGLLGGLGDWVAIGLA 61 Query: 63 HGFALFVAVAIGANISGGHVNPAVTFGLAVGGQITVITGVFYWIAQLLGSTAACFLLKYV 122 GFA+ ++ NISG H+NPAVT GL + V Y IAQLLG+ F+ Sbjct: 62 FGFAIAASIYALGNISGCHINPAVTIGLWSVKKFPGREVVPYIIAQLLGAAFGSFIFLQC 121 Query: 123 TGGLAVPTHSVA-----AGLGSIEGVVMEIIITFALVYTVYATAADPKKGSLGTIAPLAI 177 G A + G+ + ++ E++ TF L+ T+ A D + + A + I Sbjct: 122 AGIGAATVGGLGATAPFPGISYWQAMLAEVVGTFLLMITIMGIAVDER--APKGFAGIII 179 Query: 178 GLIVGANILAAGPFSGGSMNPARSFGPAVAAGD------FSGHWVYWVGPLIGGGLAGLI 231 GL V I G SG S+NPAR+FGP + ++ + +Y +GP++G LA L Sbjct: 180 GLTVAGIITTLGNISGSSLNPARTFGPYLNDMIFAGTDLWNYYSIYVIGPIVGAVLAALT 239 Query: 232 YGNV 235 Y + Sbjct: 240 YQYL 243 >3C02-A nrPDB Length = 258 Score = 162 bits (411), Expect = 1e-40, Method: Composition-based stats. Identities = 52/251 (20%), Positives = 93/251 (37%), Gaps = 30/251 (11%) Query: 13 FSLASLRAYLAEFISTLLFVFAGVGSAIAYAKLTSDAALDTPGLVAIAVCHGFALFVAVA 72 F + +R ++ EF+ T + +F G G+ + + + + G A+F + Sbjct: 5 FYKSYVREFIGEFLGTFVLMFLGEGATANF-----HTTGLSGDWYKLCLGWGLAVFFGIL 59 Query: 73 IGANISGGHVNPAVTFGLAVGGQITVITGVFYWIAQLLGSTAAC----FLLKYVTGGLAV 128 + A +SG H+N AV+ GL+ + + Y+ AQLLG+ L + Sbjct: 60 VSAKLSGAHLNLAVSIGLSSINKFDLKKIPVYFFAQLLGAFVGTSTVYGLYHGFISNSKI 119 Query: 129 PTHSVA----AGLGSIEGVVMEIIITFALVYTVYATAADPKKGSLGTIAPLAIGLIVGAN 184 P + + E+I+T L+ + + G L + +VG Sbjct: 120 PQFAWETSRNPSISLTGAFFNELILTGILLLVILVVVDE---NICGKFHILKLSSVVGLI 176 Query: 185 ILAAGPF----SGGSMNPARS----------FGPAVAAGDFSGHWVYWVGPLIGGGLAGL 230 IL G +G ++NP+R +G D WV V P +G + Sbjct: 177 ILCIGITFGGNTGFALNPSRDLGSRFLSLIAYGKDTFTKDNFYFWVPLVAPCVGSVVFCQ 236 Query: 231 IYGNVFMGSSE 241 Y V + Sbjct: 237 FYDKVICPLVD 247 >3NE2-A nrPDB Length = 246 Score = 162 bits (410), Expect = 1e-40, Method: Composition-based stats. Identities = 64/244 (26%), Positives = 101/244 (41%), Gaps = 24/244 (9%) Query: 14 SLASLRAYLAEFISTLLFVFAGVGSAIAYAKLTSDAALDT------------PGLVAIAV 61 ++ + + AE + T + VF G G+A+ + + A AI + Sbjct: 2 TMTLAKRFTAEVVGTFILVFFGPGAAVITLMIANGADKPNEFNIGIGALGGLGDWFAIGM 61 Query: 62 CHGFALFVAVAIGANISGGHVNPAVTFGLAVGGQITVITGVFYWIAQLLGSTAACFLLKY 121 A+ + ISG H+NPAVT L G+ V Y +AQ +G+ L Sbjct: 62 AFALAIAAVIYSLGRISGAHINPAVTIALWSIGRFPGREVVPYIVAQFIGAALGSLLFLA 121 Query: 122 VTGGLAVPTHSVA-----AGLGSIEGVVMEIIITFALVYTVYATAADPKKGSLGTIAPLA 176 G A + G+G + ++ E I TF L+ + A D + A L Sbjct: 122 CVGPAAATVGGLGATAPFPGIGYGQAILTEAIGTFLLMLVIMGVAVDERAPP--GFAGLV 179 Query: 177 IGLIVGANILAAGPFSGGSMNPARSFGPAVAA-----GDFSGHWVYWVGPLIGGGLAGLI 231 IGL VG I G +G S+NPAR+FGP + + +Y +GP++G A + Sbjct: 180 IGLTVGGIITTIGNITGSSLNPARTFGPYLGDSLMGINLWQYFPIYVIGPIVGAVAAAWL 239 Query: 232 YGNV 235 Y + Sbjct: 240 YNYL 243 Score = 36.5 bits (83), Expect = 0.010, Method: Composition-based stats. Identities = 28/113 (24%), Positives = 45/113 (39%), Gaps = 14/113 (12%) Query: 15 LASLRAYLAEFISTLLFVFAGVGSAIAYAKLTSDAALDTPGLVAIAVCHGFALFVAVAIG 74 + +A L E I T L + +G A+ A + G + + Sbjct: 142 IGYGQAILTEAIGTFLLMLVIMGVAVDERAPPGFAG----------LVIGLTVGGIITTI 191 Query: 75 ANISGGHVNPAVTFGLAVGGQITVITG----VFYWIAQLLGSTAACFLLKYVT 123 NI+G +NPA TFG +G + I Y I ++G+ AA +L Y+ Sbjct: 192 GNITGSSLNPARTFGPYLGDSLMGINLWQYFPIYVIGPIVGAVAAAWLYNYLA 244 >1LDI-A nrPDB Length = 281 Score = 159 bits (403), Expect = 9e-40, Method: Composition-based stats. Identities = 66/251 (26%), Positives = 104/251 (41%), Gaps = 39/251 (15%) Query: 20 AYLAEFISTLLFVFAGVGSAIAYAKLTSDAALDTPGLVAIAVCHGFALFVAVAIGANISG 79 +AEF+ T L +F GVG A A + G I+V G + +A+ + A +SG Sbjct: 10 QCIAEFLGTGLLIFFGVGCVAAL-----KVAGASFGQWEISVIWGLGVAMAIYLTAGVSG 64 Query: 80 GHVNPAVTFGLAVGGQITVITGVFYWIAQLLGSTAAC---FLLKYVTGGLAVPTHSVAAG 136 H+NPAVT L + + + ++Q+ G+ A + L Y TH + G Sbjct: 65 AHLNPAVTIALWLFACFDKRKVIPFIVSQVAGAFCAAALVYGLYYNLFFDFEQTHHIVRG 124 Query: 137 ------------------LGSIEGVVMEIIITFALVYTVYATAADPKKGSLGTIAPLAIG 178 + ++ +E++IT L+ + A D G +APL IG Sbjct: 125 SVESVDLAGTFSTYPNPHINFVQAFAVEMVITAILMGLILALTDDGNGVPRGPLAPLLIG 184 Query: 179 LIVGANILAAGPFSGGSMNPARSFGPAVAA-------------GDFSGHWVYWVGPLIGG 225 L++ + GP +G +MNPAR FGP V A D V GP++G Sbjct: 185 LLIAVIGASMGPLTGFAMNPARDFGPKVFAWLAGWGNVAFTGGRDIPYFLVPLFGPIVGA 244 Query: 226 GLAGLIYGNVF 236 + Y + Sbjct: 245 IVGAFAYRKLI 255 >6F7H-A nrPDB Length = 301 Score = 157 bits (398), Expect = 3e-39, Method: Composition-based stats. Identities = 56/244 (22%), Positives = 96/244 (39%), Gaps = 33/244 (13%) Query: 19 RAYLAEFISTLLFVFAGVGSAIAYAKLTSDAALDTPGLVAIAVCHGFALFVAVAIGANIS 78 R LAEF+ + + G A+A A + + + + + A+ +A+ +G N+S Sbjct: 22 RQCLAEFLGVFVLMLLTQG-AVAQAVTSGETKGN---FFTMFLAGSLAVTIAIYVGGNVS 77 Query: 79 GGHVNPAVTFGLAVGGQITVITGVFYWIAQLLGSTAACFLLK---------YVTGGLAVP 129 G H+NPA + + + G++ + Y + QLL + A Y G L V Sbjct: 78 GAHLNPAFSLAMCIVGRLPWVKLPIYILVQLLSAFCASGATYVLYHDALQNYTGGNLTVT 137 Query: 130 ---------THSVAAGLGSIEGVVMEIIITFALVYTVYATAADPKKGSLGTIAPLAIGLI 180 A L G + +++ T L+ + A KG + P+ +G++ Sbjct: 138 GPKETASIFATYPAPYLSLNNGFLDQVLGTGMLIVGLLAILDRRNKGVPAGLEPVVVGML 197 Query: 181 VGANILAAGPFSGGSMNPARSFGPAVAA-----------GDFSGHWVYWVGPLIGGGLAG 229 + A L+ G G +NPAR GP + WV V PL+G + Sbjct: 198 ILALGLSMGANCGIPLNPARDLGPRLFTYVAGWGPEVFSAGNGWWWVPVVAPLVGATVGT 257 Query: 230 LIYG 233 Y Sbjct: 258 ATYQ 261 >3LLQ-A nrPDB Length = 256 Score = 147 bits (371), Expect = 4e-36, Method: Composition-based stats. Identities = 67/226 (29%), Positives = 100/226 (44%), Gaps = 19/226 (8%) Query: 19 RAYLAEFISTLLFVFAGVGSAIAYAKLTSDAALDTPGLVAIAVCHGFALFVAVAIGANIS 78 R LAEF T VF G GSA+ A G +A+ G + IS Sbjct: 31 RKLLAEFFGTFWLVFGGCGSAVFAAAFPELGI----GFTGVALAFGLTVLTMAYAVGGIS 86 Query: 79 GGHVNPAVTFGLAVGGQITVITGVFYWIAQLLGSTAACFLLKYVTGGLA----------V 128 GGH NPAV+ GL V G+ + V Y IAQ+ G+ A L + G A Sbjct: 87 GGHFNPAVSVGLTVAGRFPASSLVPYVIAQVAGAIVAAAALYVIATGKAGIDLGGFASNG 146 Query: 129 PTHSVAAGLGSIEGVVMEIIITFALVYTVYATAADPKKGSLGTIAPLAIGLIVGANILAA 188 G + +++EII+T + + + AP+AIGL + L + Sbjct: 147 YGEHSPGGYSLVSALLIEIILTAFFLIVILGST---HGRVPAGFAPIAIGLALTLIHLIS 203 Query: 189 GPFSGGSMNPARSFGPAVAAGDFSGH--WVYWVGPLIGGGLAGLIY 232 P + S+NPARS G A+ G ++ W++W+ P++GG +I+ Sbjct: 204 IPVTNTSVNPARSTGQALFVGGWALQQLWLFWLAPIVGGAAGAVIW 249 >2O9F-A nrPDB Length = 234 Score = 142 bits (359), Expect = 1e-34, Method: Composition-based stats. Identities = 60/215 (27%), Positives = 88/215 (40%), Gaps = 21/215 (9%) Query: 18 LRAYLAEFISTLLFVFAGVGSAIAYAKLTSDAALDTPGLVAIAVCHGFALFVAVAIGANI 77 R AE T VF G GSA+ A G +A+ G + +I Sbjct: 5 FRKLAAESFGTFWLVFGGSGSAVLAAGFPELGI----GFAGVALAFGLTVLTMAFAVGHI 60 Query: 78 SGGHVNPAVTFGLAVGGQITVITGVFYWIAQLLGSTAACFLLKYVTGGLAVPT------- 130 SGGH NPAVT GL GG+ V Y IAQ++G A LL + G Sbjct: 61 SGGHFNPAVTIGLWAGGRFPAKEVVGYVIAQVVGGIVAAALLYLIASGKTGFDAAASGFA 120 Query: 131 -----HSVAAGLGSIEGVVMEIIITFALVYTVYATAADPKKGSLGTIAPLAIGLIVGANI 185 G + +V+E++++ + ++ K + AP+AIGL Sbjct: 121 SNGYGEHSPGGYSMLSALVVELVLSAGFLLVIHGATD---KFAPAGFAPIAIGLACTLIH 177 Query: 186 LAAGPFSGGSMNPARSFGPAVAAGDFSGH--WVYW 218 L + P + S+NPARS A+ G ++ W +W Sbjct: 178 LISIPVTNTSVNPARSTAVAIFQGGWALEQLWFFW 212 >4AGS-A nrPDB Length = 471 Score = 29.6 bits (65), Expect = 1.4, Method: Composition-based stats. Identities = 10/34 (29%), Positives = 16/34 (47%) Query: 214 HWVYWVGPLIGGGLAGLIYGNVFMGSSEHVPLAS 247 H V P++G ++Y N+F + LAS Sbjct: 238 HLVPESAPMMGANGGHVLYSNLFCPFVDRARLAS 271 >6BH8-A nrPDB Length = 483 Score = 26.9 bits (58), Expect = 7.8, Method: Composition-based stats. Identities = 24/177 (13%), Positives = 47/177 (26%), Gaps = 32/177 (18%) Query: 14 SLASLRAYLAEFISTLLFVFAGVGSAIAYAK-LTSDAALDTPGLVAIAVCHGFALFVAVA 72 + + +E TL+ +F G+ + A + ++ L + Sbjct: 76 TFSFWSGLYSETEGTLILLFGGIPYLWRLSGRFCGYAGFGPEYEITQSLVF-LLLATLFS 134 Query: 73 IGANISGGHVNPAV----------TFGLAVGGQITVITGVFYWIAQLLGSTAACFLLKYV 122 A + N V T G + I + + Q + + LL + Sbjct: 135 ALAGLPWSLYNTFVIEEKHGFNQQTLGFFMKDAIKK-----FVVTQCILLPVSSLLLYII 189 Query: 123 -TGGLAVPTHSVAAGLGSIEGVVMEIIITFALVYTVYATAADPKKGSLGTIAPLAIG 178 GG ++ + T + + AD PL G Sbjct: 190 KIGGDYFFIYAW--------------LFTLVVSLVLVTIYADYIAPLFDKFTPLPEG 232 >3NWO-A nrPDB Length = 330 Score = 26.5 bits (57), Expect = 9.9, Method: Composition-based stats. Identities = 10/19 (52%), Positives = 12/19 (63%) Query: 232 YGNVFMGSSEHVPLASADF 250 Y V G+S H+P A ADF Sbjct: 88 YDQVGCGNSTHLPDAPADF 106 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.318 0.139 0.376 Lambda K H 0.267 0.0424 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 9,197,139 Number of Sequences: 36641 Number of extensions: 352048 Number of successful extensions: 1192 Number of sequences better than 10.0: 47 Number of HSP's better than 10.0 without gapping: 55 Number of HSP's successfully gapped in prelim test: 33 Number of HSP's that attempted gapping in prelim test: 952 Number of HSP's gapped (non-prelim): 98 length of query: 250 length of database: 10,336,785 effective HSP length: 95 effective length of query: 155 effective length of database: 6,855,890 effective search space: 1062662950 effective search space used: 1062662950 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 58 (26.9 bits)