BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q39172 (345 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 2J3K-A nrPDB 714 0.0 1V3V-A nrPDB 236 9e-63 2Y05-A nrPDB 226 1e-59 2VNA-A nrPDB 179 2e-45 2ZB3-A nrPDB 174 4e-44 2WEK-A nrPDB 107 9e-24 1YB5-A nrPDB 64 1e-10 2OBY-A nrPDB 57 2e-08 5K1S-A nrPDB 55 6e-08 4RVS-A nrPDB 53 2e-07 3QWB-A nrPDB 53 2e-07 5A3V-A nrPDB 49 4e-06 1WLY-A nrPDB 48 5e-06 1O89-A nrPDB 48 6e-06 2VCY-A nrPDB 48 7e-06 3UOG-A nrPDB 47 1e-05 3TQH-A nrPDB 45 3e-05 3FBG-A nrPDB 45 5e-05 4A27-A nrPDB 45 5e-05 3SLK-A nrPDB 44 1e-04 1QOR-A nrPDB 42 4e-04 4J6F-A nrPDB 41 7e-04 5ENV-A nrPDB 40 0.001 2DFV-A nrPDB 38 0.006 3JYN-A nrPDB 37 0.009 3HZZ-A nrPDB 32 0.27 4EYE-A nrPDB 32 0.31 4PVC-A nrPDB 32 0.33 3RSH-A nrPDB 32 0.37 5B6K-A nrPDB 32 0.43 1WZA-A nrPDB 32 0.50 5YWN-A nrPDB 31 0.72 3DAF-A nrPDB 30 1.1 4IDE-A nrPDB 30 1.3 4RJ9-A nrPDB 30 2.0 4A10-A nrPDB 28 6.0 5D6S-A nrPDB 28 7.2 6F3T-A nrPDB 28 7.6 3FPC-A nrPDB 28 8.0 2OUI-A nrPDB 28 8.0 6MZM-G nrPDB 27 9.1 >2J3K-A nrPDB Length = 345 Score = 714 bits (1843), Expect = 0.0, Method: Compositional matrix adjust. Identities = 344/345 (99%), Positives = 344/345 (99%) Query: 1 MTATNKQVILKDYVSGFPTESDFDFTTTTVELRVPEGTNSVLVKNLYLSCDPYMRIRMGK 60 MTATNKQVILKDYVSGFPTESDFDFTTTTVELRVPEGTNSVLVKNLYLSCDPYMRIRMGK Sbjct: 1 MTATNKQVILKDYVSGFPTESDFDFTTTTVELRVPEGTNSVLVKNLYLSCDPYMRIRMGK 60 Query: 61 PDPSTAALAQAYTPGQPIQGYGVSRIIESGHPDYKKGDLLWGIVAWEEYSVITPMTHAHF 120 PDPSTAALAQAYTPGQPIQGYGVSRIIESGHPDYKKGDLLWGIVAWEEYSVITPMTHAHF Sbjct: 61 PDPSTAALAQAYTPGQPIQGYGVSRIIESGHPDYKKGDLLWGIVAWEEYSVITPMTHAHF 120 Query: 121 KIQHTDVPLSYYTGLLGMPGMTAYAGFYEVCSPKEGETVYVSAASGAVGQLVGQLAKMMG 180 KIQHTDVPLSYYTGLLGMPGMTAYAGFYEVCSPKEGETVYVSAASGAVGQLVGQLAKMMG Sbjct: 121 KIQHTDVPLSYYTGLLGMPGMTAYAGFYEVCSPKEGETVYVSAASGAVGQLVGQLAKMMG 180 Query: 181 CYVVGSAGSKEKVDLLKTKFGFDDAFNYKEESDLTAALKRCFPNGIDIYFENVGGKMLDA 240 CYVVGSAGSKEKVDLLKTKFGFDDAFNYKEESDLTAALKRCFPNGIDIYFENVGGKMLDA Sbjct: 181 CYVVGSAGSKEKVDLLKTKFGFDDAFNYKEESDLTAALKRCFPNGIDIYFENVGGKMLDA 240 Query: 241 VLVNMNMHGRIAVCGMISQYNLENQEGVHNLSNIIYKRIRIQGFVVSDFYDKYSKFLEFV 300 VLVNMNMHGRIAVCGMISQYNLENQEGVHNLSNIIYKR RIQGFVVSDFYDKYSKFLEFV Sbjct: 241 VLVNMNMHGRIAVCGMISQYNLENQEGVHNLSNIIYKRNRIQGFVVSDFYDKYSKFLEFV 300 Query: 301 LPHIREGKITYVEDVADGLEKAPEALVGLFHGKNVGKQVVVVARE 345 LPHIREGKITYVEDVADGLEKAPEALVGLFHGKNVGKQVVVVARE Sbjct: 301 LPHIREGKITYVEDVADGLEKAPEALVGLFHGKNVGKQVVVVARE 345 >1V3V-A nrPDB Length = 333 Score = 236 bits (603), Expect = 9e-63, Method: Compositional matrix adjust. Identities = 143/338 (42%), Positives = 195/338 (57%), Gaps = 18/338 (5%) Query: 6 KQVILKDYVSGFPTESDFDFTTTTVELRVPEGTNSVLVKNLYLSCDPYMRIRMGKPDPST 65 K LK + G PT+SDF+ T VEL P VL++ L+LS DPYMRI Sbjct: 9 KSWTLKKHFQGKPTQSDFELKT--VELP-PLKNGEVLLEALFLSVDPYMRIA-------- 57 Query: 66 AALAQAYTPGQPIQGYGVSRIIESGHPDYKKGDLLWGIVAWEEYSVITPMTHAHFKIQHT 125 ++ G + G V+R++ES + + G ++ W + + + Sbjct: 58 ---SKRLKEGAVMMGQQVARVVESKNSAFPAGSIVLAQSGWTTHFISDGKGLEKLLTEWP 114 Query: 126 D-VPLSYYTGLLGMPGMTAYAGFYEVCSPKEGETVYVSAASGAVGQLVGQLAKMMGCYVV 184 D +PLS G +GMPG+TAY G EVC K GETV VSAA+GAVG +VGQ+AK+ GC VV Sbjct: 115 DKLPLSLALGTIGMPGLTAYFGLLEVCGVKGGETVLVSAAAGAVGSVVGQIAKLKGCKVV 174 Query: 185 GSAGSKEKVDLLKTKFGFDDAFNYKEESDLTAALKRCFPNGIDIYFENVGGKMLDAVLVN 244 G+AGS EK+ LK + GFD AFNYK + L ALK+ P+G D YF+NVGG+ L+ VL Sbjct: 175 GAAGSDEKIAYLK-QIGFDAAFNYKTVNSLEEALKKASPDGYDCYFDNVGGEFLNTVLSQ 233 Query: 245 MNMHGRIAVCGMISQYNLENQ-EGVHNLSNIIYKRIRIQGFVVSDFY-DKYSKFLEFVLP 302 M G+IA+CG IS YN +Q + +IIYK++RI+GF+V + D K L ++ Sbjct: 234 MKDFGKIAICGAISVYNRMDQLPPGPSPESIIYKQLRIEGFIVYRWQGDVREKALRDLMK 293 Query: 303 HIREGKITYVEDVADGLEKAPEALVGLFHGKNVGKQVV 340 + EGKI Y E V G E P A + + +G N+GK VV Sbjct: 294 WVLEGKIQYHEHVTKGFENMPAAFIEMLNGANLGKAVV 331 >2Y05-A nrPDB Length = 328 Score = 226 bits (576), Expect = 1e-59, Method: Compositional matrix adjust. Identities = 132/341 (38%), Positives = 187/341 (54%), Gaps = 18/341 (5%) Query: 3 ATNKQVILKDYVSGFPTESDFDFTTTTVELRVPEGTNSVLVKNLYLSCDPYMRIRMGKPD 62 + K LK + G+PT SDF+ T+ + P VL++ L+L+ DPYMR+ Sbjct: 1 SMTKTWTLKKHFVGYPTNSDFELKTSELP---PLKNGEVLLEALFLTVDPYMRVA----- 52 Query: 63 PSTAALAQAYTPGQPIQGYGVSRIIESGHPDYKKGDLLWGIVAWEEYSVITPMTHAHFKI 122 A+ G + G V++++ES + KG ++ W +S+ Sbjct: 53 ------AKRLKEGDTMMGQQVAKVVESKNVALPKGTIVLASPGWTTHSISDGKDLEKLLT 106 Query: 123 QHTD-VPLSYYTGLLGMPGMTAYAGFYEVCSPKEGETVYVSAASGAVGQLVGQLAKMMGC 181 + D +PLS G +GMPG+TAY G E+C K GETV V+AA+GAVG +VGQ+AK+ GC Sbjct: 107 EWPDTIPLSLALGTVGMPGLTAYFGLLEICGVKGGETVMVNAAAGAVGSVVGQIAKLKGC 166 Query: 182 YVVGSAGSKEKVDLLKTKFGFDDAFNYKEESDLTAALKRCFPNGIDIYFENVGGKMLDAV 241 VVG+ GS EKV L+ K GFD FNYK L LK+ P+G D YF+NVGG+ + V Sbjct: 167 KVVGAVGSDEKVAYLQ-KLGFDVVFNYKTVESLEETLKKASPDGYDCYFDNVGGEFSNTV 225 Query: 242 LVNMNMHGRIAVCGMISQYNLENQEGVHNLSNI-IYKRIRIQGFVVSDFY-DKYSKFLEF 299 + M GRIA+CG IS YN I IY+ +R++ FVV + D K L+ Sbjct: 226 IGQMKKFGRIAICGAISTYNRTGPLPPGPPPEIVIYQELRMEAFVVYRWQGDARQKALKD 285 Query: 300 VLPHIREGKITYVEDVADGLEKAPEALVGLFHGKNVGKQVV 340 +L + EGKI Y E + +G E P A +G+ G N+GK +V Sbjct: 286 LLKWVLEGKIQYKEYIIEGFENMPAAFMGMLKGDNLGKTIV 326 >2VNA-A nrPDB Length = 357 Score = 179 bits (453), Expect = 2e-45, Method: Compositional matrix adjust. Identities = 118/347 (34%), Positives = 176/347 (50%), Gaps = 29/347 (8%) Query: 15 SGFPTESDFDFTTTTVELRVPEGTNSVLVKNLYLSCDPYMRIRMGKPDPSTAALAQAYTP 74 +G P +F + + EG V V+ LYLS DPYMR RM + D T + + Sbjct: 16 NGNPVAENFRMEEVYLPDNINEG--QVQVRTLYLSVDPYMRCRMNE-DTGTDYIT-PWQL 71 Query: 75 GQPIQGYGVSRIIESGHPDYKKGDLL----WGIVAWEEYSVITPMTHAHFKIQHTDVPLS 130 Q + G G+ I ES H + KGD + W W+ ++ + Q D LS Sbjct: 72 SQVVDGGGIGIIEESKHTNLTKGDFVTSFYW---PWQTKVILDGNSLEKVDPQLVDGHLS 128 Query: 131 YYTGLLGMPGMTAYAGFYEVCSPKEG--ETVYVSAASGAVGQLVGQLAKMMGC-YVVGSA 187 Y+ G +GMPG+T+ G E G +T+ VS A+GA G + GQ+ +GC VVG Sbjct: 129 YFLGAIGMPGLTSLIGIQEKGHITAGSNKTMVVSGAAGACGSVAGQIGHFLGCSRVVGIC 188 Query: 188 GSKEKVDLLKTKFGFDDAFNYKEESDLTAALKRCFPNGIDIYFENVGGKMLDAVLVNMNM 247 G+ EK LL ++ GFD A NYK++ ++ L+ P G+D+YF+NVGG + D V+ MN Sbjct: 189 GTHEKCILLTSELGFDAAINYKKD-NVAEQLRESCPAGVDVYFDNVGGNISDTVISQMNE 247 Query: 248 HGRIAVCGMISQYNLE---------NQEGVHNLSNIIYKRIRIQGFVVSDFYDKYSKFLE 298 + I +CG ISQYN + E + NI +R F+V ++ DK+ + Sbjct: 248 NSHIILCGQISQYNKDVPYPPPLSPAIEAIQKERNITRER-----FLVLNYKDKFEPGIL 302 Query: 299 FVLPHIREGKITYVEDVADGLEKAPEALVGLFHGKNVGKQVVVVARE 345 + +EGK+ E V +GLE A + G N+GKQ+V ++ E Sbjct: 303 QLSQWFKEGKLKIKETVINGLENMGAAFQSMMTGGNIGKQIVCISEE 349 >2ZB3-A nrPDB Length = 353 Score = 174 bits (442), Expect = 4e-44, Method: Compositional matrix adjust. Identities = 115/333 (34%), Positives = 170/333 (51%), Gaps = 29/333 (8%) Query: 31 ELRVPEGTN--SVLVKNLYLSCDPYMRIRMGKPDPSTAALAQAYTPGQPIQGYGVSRIIE 88 E +P+ N V V+ LYLS DPYMR +M + D T LA + Q G G+ + E Sbjct: 29 EFSLPDALNEGQVQVRTLYLSVDPYMRCKMNE-DTGTDYLA-PWQLAQVADGGGIGVVEE 86 Query: 89 SGHPDYKKGDLL----WGIVAWEEYSVITPMTHAHFKIQHTDVPLSYYTGLLGMPGMTAY 144 S H KGD + W W+ +++ Q D LSY+ G +GMPG+T+ Sbjct: 87 SKHQKLTKGDFVTSFYW---PWQTKAILDGNGLEKVDPQLVDGHLSYFLGAIGMPGLTSL 143 Query: 145 AGFYEV--CSPKEGETVYVSAASGAVGQLVGQLAKMMGC-YVVGSAGSKEKVDLLKTKFG 201 G E S +T+ VS A+GA G L GQ+ ++GC VVG G++EK L ++ G Sbjct: 144 IGVQEKGHISAGSNQTMVVSGAAGACGSLAGQIGHLLGCSRVVGICGTQEKCLFLTSELG 203 Query: 202 FDDAFNYKEESDLTAALKRCFPNGIDIYFENVGGKMLDAVLVNMNMHGRIAVCGMISQYN 261 FD A NYK ++ L+ P G+D+YF+NVGG + +AV+ MN + I +CG ISQY+ Sbjct: 204 FDAAVNYKT-GNVAEQLREACPGGVDVYFDNVGGDISNAVISQMNENSHIILCGQISQYS 262 Query: 262 LENQ---------EGVHNLSNIIYKRIRIQGFVVSDFYDKYSKFLEFVLPHIREGKITYV 312 + E + NI +R F V ++ DK+ + + +EGK+ Sbjct: 263 NDVPYPPPLPPAVEAIRKERNITRER-----FTVLNYKDKFEPGILQLSQWFKEGKLKVK 317 Query: 313 EDVADGLEKAPEALVGLFHGKNVGKQVVVVARE 345 E +A GLE A + G NVGKQ+V ++ + Sbjct: 318 ETMAKGLENMGVAFQSMMTGGNVGKQIVCISED 350 >2WEK-A nrPDB Length = 341 Score = 107 bits (266), Expect = 9e-24, Method: Compositional matrix adjust. Identities = 83/264 (31%), Positives = 124/264 (46%), Gaps = 27/264 (10%) Query: 101 WGIVAWEEYSV---ITPMTHAHFKIQHTDVPLSYYTGL---------LGMPGMTAYAGFY 148 G+ A Y+V + M F ++T VP S T + L + G TAY Sbjct: 77 LGLSASARYTVGQAVAYMAPGSFA-EYTVVPASIATPVPSVKPEYLTLLVSGTTAYISLK 135 Query: 149 EVCSPKEGETVYVSAASGAVGQLVGQLAKMMGCYVVGSAGSKEKVDLLKTKFGFDDAFNY 208 E+ EG+ V V+AA+G GQ QL+K C+V+G+ S EK LK+ G D NY Sbjct: 136 ELGGLSEGKKVLVTAAAGGTGQFAMQLSKKAKCHVIGTCSSDEKSAFLKS-LGCDRPINY 194 Query: 209 KEESDLTAALKRCFPNGIDIYFENVGGKMLDAVLVNMNMHGRIAVCGMISQYN----LEN 264 K E + LK+ +P G+D+ +E+VGG M D + + GR+ V G IS Y L Sbjct: 195 KTEP-VGTVLKQEYPEGVDVVYESVGGAMFDLAVDALATKGRLIVIGFISGYQTPTGLSP 253 Query: 265 QEGVHNLSNIIYKRIRIQGFVVSDFYDKYSKFLEFVLPHIREGKITYVEDVAD------- 317 + + ++ K +QGF ++ + KY + +L G + D+ D Sbjct: 254 VKAGTLPAKLLKKSASVQGFFLNHYLSKYQAAMSHLLEMCVSGDLVCEVDLGDLSPEGRF 313 Query: 318 -GLEKAPEALVGLFHGKNVGKQVV 340 GLE A+ ++ GKN GK VV Sbjct: 314 TGLESIFRAVNYMYMGKNTGKIVV 337 >1YB5-A nrPDB Length = 351 Score = 63.5 bits (153), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 71/280 (25%), Positives = 122/280 (43%), Gaps = 26/280 (9%) Query: 72 YTPGQPIQGYGVSRIIESGHPDYKKGDLLWGIV----AWEEYSVITPMTHAHFKIQHTDV 127 YTPG + G V + +KKGD ++ + EY++ H +K+ Sbjct: 89 YTPGSDVAG--VIEAVGDNASAFKKGDRVFTSSTISGGYAEYAL--AADHTVYKLPEK-- 142 Query: 128 PLSYYTGL-LGMPGMTAYAGFYEVCSPKEGETVYVSAASGAVGQLVGQLAKMMGCYVVGS 186 L + G +G+P TAY K GE+V V ASG VG Q+A+ G ++G+ Sbjct: 143 -LDFKQGAAIGIPYFTAYRALIHSACVKAGESVLVHGASGGVGLAACQIARAYGLKILGT 201 Query: 187 AGSKEKVDLLKTKFGFDDAFNYKEESDLTAALKRCFPNGIDIYFENVGGKMLDAVLVNMN 246 AG++E ++ + G + FN++E + + K GIDI E + L L ++ Sbjct: 202 AGTEEGQKIV-LQNGAHEVFNHREVNYIDKIKKYVGEKGIDIIIEMLANVNLSKDLSLLS 260 Query: 247 MHGRIAVCGMISQYNLENQEGVHNLSNIIYKRIRIQGFVVSDFYDKYSKFLEFVLPHIRE 306 GR+ V G + ++ + S+II V+ F +F ++ Sbjct: 261 HGGRVIVVGSRGTIEINPRDTMAKESSIIG---------VTLFSSTKEEFQQYAAALQAG 311 Query: 307 GKITYVEDVADG---LEKAPEALVGLFHGKN-VGKQVVVV 342 +I +++ V LEK EA + HG GK ++++ Sbjct: 312 MEIGWLKPVIGSQYPLEKVAEAHENIIHGSGATGKMILLL 351 >2OBY-A nrPDB Length = 338 Score = 56.6 bits (135), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 53/208 (25%), Positives = 99/208 (47%), Gaps = 13/208 (6%) Query: 141 MTAYAGFYEVCSPKEGETVYVSAASGAVGQLVGQLAKMMGCYVVGSAGSKEKVDLLKTKF 200 +TA+ + V + + G+ V + A VG QL +M G + +AGS++K+ + + K Sbjct: 132 LTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQMAE-KL 190 Query: 201 GFDDAFNYKEESDLTAALKRCFPNGIDIYFENVGGKMLDAVLVNMNMHGRIAVCGMISQY 260 G FNYK+E A LK G+++ + +GG + + + + GR + G++ Sbjct: 191 GAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIGGSYWEKNVNCLALDGRWVLYGLMGGG 250 Query: 261 NLENQEGVHNLSNIIYKRIRIQGFVVSDFYDKYSK-----FLEFVLPHIR-EG--KITYV 312 ++ S +++KR + ++ +KY + F E +LPH EG ++ V Sbjct: 251 DINGPL----FSKLLFKRGSLITSLLRSRDNKYKQMLVNAFTEQILPHFSTEGPQRLLPV 306 Query: 313 EDVADGLEKAPEALVGLFHGKNVGKQVV 340 D + + EA + KN+GK V+ Sbjct: 307 LDRIYPVTEIQEAHKYMEANKNIGKIVL 334 >5K1S-A nrPDB Length = 362 Score = 54.7 bits (130), Expect = 6e-08, Method: Compositional matrix adjust. Identities = 43/130 (33%), Positives = 61/130 (46%), Gaps = 6/130 (4%) Query: 154 KEGETVYVSAASGAVGQLVGQLAKMMGCYVVGSAGSKEKVDLLKTKFGFDDAFNYKEESD 213 + GETV ++ ASG VG QLA++ G V+ S+ KV LK + G D+ + Sbjct: 182 RAGETVLITGASGGVGLSSVQLARLDGARVIAVTSSEAKVQALK-EAGADEVIVSRGLDF 240 Query: 214 LTAALKRCFPNGIDIYFENVGGKMLDAVLVNMNMHGRIAVCGMISQYNLENQEGVHNLSN 273 + KR G+D+ E VG D L +M GR+ V G NLE+ N Sbjct: 241 ASDVRKRTQGAGVDVAVEIVGSATFDQTLKSMAPGGRVVVVG-----NLESGMVQLNPGL 295 Query: 274 IIYKRIRIQG 283 +I K + I G Sbjct: 296 VIVKELEILG 305 >4RVS-A nrPDB Length = 329 Score = 52.8 bits (125), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 37/123 (30%), Positives = 59/123 (47%), Gaps = 3/123 (2%) Query: 138 MPGMTAYAGFYEVCSPKEGETVYVSAASGAVGQLVGQLAKMMGCYVVGSAGSKEKVDLLK 197 + G+TA+ V K G+TV V A +G VG ++ Q A +G V+ + + EK L K Sbjct: 125 LKGLTAHYLLKSVYPVKRGDTVLVHAGAGGVGLILTQWATHLGVRVITTVSTAEKAKLSK 184 Query: 198 TKFGFDDAFNYKEESDLTAALKRCFP--NGIDIYFENVGGKMLDAVLVNMNMHGRIAVCG 255 G D +Y E++ A R G+ ++ VG DA L ++ + G +A+ G Sbjct: 185 DA-GADVVLDYPEDAWQFAGRVRELTGGTGVQAVYDGVGATTFDASLASLAVRGTLALFG 243 Query: 256 MIS 258 S Sbjct: 244 AAS 246 >3QWB-A nrPDB Length = 334 Score = 52.8 bits (125), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 39/128 (30%), Positives = 62/128 (48%), Gaps = 3/128 (2%) Query: 131 YYTGLLGMPGMTAYAGFYEVCSPKEGETVYVSAASGAVGQLVGQLAKMMGCYVVGSAGSK 190 Y GLL + +TA + E K+G+ V + AA+G VG ++ QL KM G + + A + Sbjct: 126 YAAGLLQV--LTALSFTNEAYHVKKGDYVLLFAAAGGVGLILNQLLKMKGAHTIAVASTD 183 Query: 191 EKVDLLKTKFGFDDAFNYKEESDLTAALKRCFPNGIDIYFENVGGKMLDAVLVNMNMHGR 250 EK+ + K ++G + N +E L LK G+D F++VG + L + G Sbjct: 184 EKLKIAK-EYGAEYLINASKEDILRQVLKFTNGKGVDASFDSVGKDTFEISLAALKRKGV 242 Query: 251 IAVCGMIS 258 G S Sbjct: 243 FVSFGNAS 250 >5A3V-A nrPDB Length = 329 Score = 48.5 bits (114), Expect = 4e-06, Method: Compositional matrix adjust. Identities = 52/209 (24%), Positives = 91/209 (43%), Gaps = 16/209 (7%) Query: 133 TGLLGMPGMTAYAGFYEVCSPKEGETVYVSAASGAVGQLVGQLAKMMGCYVVGSAGSKEK 192 GL + +T AG + K+ + V+AASG VG QLAK+ +V + G++ Sbjct: 134 AGLTALQALTNPAGLKLDGTGKKA-NILVTAASGGVGHYAVQLAKLANAHVTATCGARN- 191 Query: 193 VDLLKTKFGFDDAFNYKEESDLTAALKRCFPNGIDIYFENVGGKMLDAVLVNMNMHGRIA 252 ++ +K+ G D+ +YK AALK D G N++ +G++ Sbjct: 192 IEFVKS-LGADEVLDYKTPEG--AALKSPSGKKYDAVVHCANGIPFSVFEPNLSENGKV- 247 Query: 253 VCGMISQYNLENQEGVHNLSNIIYKRIRI-QGFVVSDFYDKYSKFLEFVLPHIREGKITY 311 ++ G + + K+I + + +V ++ LEF++ ++EGK+ Sbjct: 248 ---------IDITPGPNAMWTYAVKKITMSKKQLVPLLLIPKAENLEFMVNLVKEGKVKT 298 Query: 312 VEDVADGLEKAPEALVGLFHGKNVGKQVV 340 V D L KA +A G GK +V Sbjct: 299 VIDSKHPLSKAEDAWAKSIDGHATGKIIV 327 >1WLY-A nrPDB Length = 333 Score = 48.1 bits (113), Expect = 5e-06, Method: Compositional matrix adjust. Identities = 32/128 (25%), Positives = 60/128 (46%), Gaps = 2/128 (1%) Query: 131 YYTGLLGMPGMTAYAGFYEVCSPKEGETVYVSAASGAVGQLVGQLAKMMGCYVVGSAGSK 190 + GL+ + GMTA ++ K G+ V + AA+G +G ++ A+ +G V+G+ ++ Sbjct: 122 HLAGLM-LKGMTAQYLLHQTHKVKPGDYVLIHAAAGGMGHIMVPWARHLGATVIGTVSTE 180 Query: 191 EKVDLLKTKFGFDDAFNYKEESDLTAALKRCFPNGIDIYFENVGGKMLDAVLVNMNMHGR 250 EK + + K G NY + + G+D+ ++++G L L + G Sbjct: 181 EKAETAR-KLGCHHTINYSTQDFAEVVREITGGKGVDVVYDSIGKDTLQKSLDCLRPRGM 239 Query: 251 IAVCGMIS 258 A G S Sbjct: 240 CAAYGHAS 247 >1O89-A nrPDB Length = 345 Score = 48.1 bits (113), Expect = 6e-06, Method: Compositional matrix adjust. Identities = 39/131 (29%), Positives = 59/131 (45%), Gaps = 11/131 (8%) Query: 153 PKEGETVYVSAASGAVGQLVGQLAKMMGCYVVGSAGSKEKVDLLKTKFGFDDAFNYKEES 212 P++GE V V+ ASG VG L +G VV +G + + LK+ G E + Sbjct: 166 PQDGEIV-VTGASGGVGSTAVALLHKLGYQVVAVSGRESTHEYLKS-LGASRVLPRDEFA 223 Query: 213 DLTAALKRCFPNGIDIYFENVGGKMLDAVLVNMNMHGRIAVCGMISQYNLENQEGVHNLS 272 + K+ + ID VG K+L VL MN G +A CG+ + L + Sbjct: 224 ESRPLEKQVWAGAID----TVGDKVLAKVLAQMNYGGCVAACGLAGGFTLPT-----TVM 274 Query: 273 NIIYKRIRIQG 283 I + +R+QG Sbjct: 275 PFILRNVRLQG 285 >2VCY-A nrPDB Length = 344 Score = 47.8 bits (112), Expect = 7e-06, Method: Compositional matrix adjust. Identities = 57/245 (23%), Positives = 107/245 (43%), Gaps = 27/245 (11%) Query: 82 GVSRIIESGH--PDYKKGDLLW------GIVAWEEYSVITPMTHAHFKIQHTDVPLSYYT 133 GV++++ G K GD W G+ W +V + A ++ +D+PL Sbjct: 79 GVAQVVAVGSNVTGLKPGD--WVIPANAGLGTWRTEAVFS--EEALIQV-PSDIPLQS-A 132 Query: 134 GLLGMPGMTAYAGFYEVCSPKEGETVYVSAASGAVGQLVGQLAKMMGCYVVGSAGSKEKV 193 LG+ TAY + + G++V +A++ VGQ V Q+A +G + + + Sbjct: 133 ATLGVNPCTAYRMLMDFEQLQPGDSVIQNASNSGVGQAVIQIAAALGLRTINVVRDRPDI 192 Query: 194 DLLKTKFGFDDAFNYKEESDLTAALKRCFPNGI---DIYFENVGGKMLDAVLVNMNMHGR 250 L + A + E +L + F + + VGGK +L + G Sbjct: 193 QKLSDRLKSLGAEHVITEEELRRPEMKNFFKDMPQPRLALNCVGGKSSTELLRQLARGGT 252 Query: 251 IAVCGMISQYNLENQEGVHNLSNIIYKRIRIQGFVVSDFYDKYS--KFLEFVLP---HIR 305 M++ + Q V ++S +I+K ++++GF +S + +S +F E +L IR Sbjct: 253 -----MVTYGGMAKQPVVASVSLLIFKDLKLRGFWLSQWKKDHSPDQFKELILTLCDLIR 307 Query: 306 EGKIT 310 G++T Sbjct: 308 RGQLT 312 >3UOG-A nrPDB Length = 363 Score = 47.4 bits (111), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 53/201 (26%), Positives = 83/201 (41%), Gaps = 13/201 (6%) Query: 140 GMTAYAGFYEVCSPKEGETVYVSAASGAVGQLVGQLAKMMGCYVVGSAGSKEKVDLLKTK 199 G+TA+ E + G+ V V +G V Q+AK G V+ ++ S+EK+D Sbjct: 174 GLTAWFALVEKGHLRAGDRVVVQG-TGGVALFGLQIAKATGAEVIVTSSSREKLDR-AFA 231 Query: 200 FGFDDAFNYKEESDLTAALKRCFPNGIDIYFENVGGKMLDAVLVNMNMHGRIAVCGMISQ 259 G D N EE + G D E GG L L + GRI+V G++ Sbjct: 232 LGADHGINRLEEDWVERVYALTGDRGADHILEIAGGAGLGQSLKAVAPDGRISVIGVLEG 291 Query: 260 YNLENQEGVHNLSNIIYKRIRIQGFVVSDFYDKYSKFLEFVLPHIREGKITYVEDVADGL 319 + + G ++ K +QG V + + LE ++ + + V D+ Sbjct: 292 FEVSGPVG-----PLLLKSPVVQGISVG-----HRRALEDLVGAVDRLGLKPVIDMRYKF 341 Query: 320 EKAPEALVGLFHGKNVGKQVV 340 + PEAL L G GK V+ Sbjct: 342 TEVPEALAHLDRGP-FGKVVI 361 >3TQH-A nrPDB Length = 321 Score = 45.4 bits (106), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 55/210 (26%), Positives = 88/210 (41%), Gaps = 35/210 (16%) Query: 97 GDLLWGIVAWEEYSVITPMTHAHFKIQHTDVPLSYYTGL-------LGMPGMTAYAGFYE 149 GD + GI + ++ P +A + D + L L G+TA + Sbjct: 92 GDKVMGIAGFPDH----PCCYAEYVCASPDTIIQKLEKLSFLQAASLPTAGLTALQALNQ 147 Query: 150 VCSPKEGETVYVSAASGAVGQLVGQLAKMMGCYVVGSAGSKEKVDLLKTKFGFDDAFNYK 209 K+G+ V + A +G VG L QLAK G V+ +A SK LK G + NY Sbjct: 148 A-EVKQGDVVLIHAGAGGVGHLAIQLAKQKGTTVITTA-SKRNHAFLKA-LGAEQCINYH 204 Query: 210 EESDLTAALKRCFPNGIDIYFENVGGKMLDA-------VLVNMNMHGRI---------AV 253 EE D A+ ID+ +VG + +D V V GR+ Sbjct: 205 EE-DFLLAISTPVDAVIDLVGGDVGIQSIDCLKETGCIVSVPTITAGRVIEVAKQKHRRA 263 Query: 254 CGMISQYNLENQEGVHNLSNIIYK-RIRIQ 282 G++ Q+N+E +H L ++ + ++RI+ Sbjct: 264 FGLLKQFNIEE---LHYLGKLVSEDKLRIE 290 >3FBG-A nrPDB Length = 346 Score = 45.1 bits (105), Expect = 5e-05, Method: Compositional matrix adjust. Identities = 26/81 (32%), Positives = 42/81 (51%), Gaps = 7/81 (8%) Query: 136 LGMPGMTAYAGFYEVC------SPKEGETVYVSAASGAVGQLVGQLAKMMGCYVVGSAGS 189 L + G+TAY ++V + EG+T+ + +G VG + Q+AK G V+ +A Sbjct: 125 LPLTGITAYETLFDVFGISRNRNENEGKTLLIINGAGGVGSIATQIAKAYGLRVITTASR 184 Query: 190 KEKVDLLKTKFGFDDAFNYKE 210 E ++ K K G D N+KE Sbjct: 185 NETIEWTK-KMGADIVLNHKE 204 >4A27-A nrPDB Length = 349 Score = 45.1 bits (105), Expect = 5e-05, Method: Compositional matrix adjust. Identities = 52/171 (30%), Positives = 76/171 (44%), Gaps = 19/171 (11%) Query: 74 PGQP-IQGYGVSRIIES---GHPDYKKGDLLWGIV---AWEEYSVITPMTHAHFKIQHTD 126 P P + G+ S I+E+ Y+ GD + V AW E V TP+ +KI D Sbjct: 58 PKTPLVPGFECSGIVEALGDSVKGYEIGDRVMAFVNYNAWAEV-VCTPVEFV-YKIPD-D 114 Query: 127 VPLSYYTGLLGMPGMTAYAGFYEVCSPKEGETVYVSAASGAVGQLVGQLAKMMGCYVVGS 186 + S M +TAY +EV + +EG +V V +A G VGQ V QL + V Sbjct: 115 MSFSEAAAF-PMNFVTAYVMLFEVANLREGMSVLVHSAGGGVGQAVAQLCSTVPNVTVFG 173 Query: 187 AGSKEKVDLLKTKFG--FDDAFNYKEESDLTAALKRCFPNGIDIYFENVGG 235 S K + +K FD +Y +E +KR G+DI + + G Sbjct: 174 TASTFKHEAIKDSVTHLFDRNADYVQE------VKRISAEGVDIVLDCLCG 218 >3SLK-A nrPDB Length = 795 Score = 43.9 bits (102), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 46/205 (22%), Positives = 89/205 (43%), Gaps = 15/205 (7%) Query: 141 MTAYAGFYEVCSPKEGETVYVSAASGAVGQLVGQLAKMMGC--YVVGSAGSKEKVDLLKT 198 +TAY ++ + GE++ V +A+G VG QLA+ +G Y S + V+L + Sbjct: 331 LTAYYALVDLAGLRPGESLLVHSAAGGVGMAAIQLARHLGAEVYATASEDKWQAVELSRE 390 Query: 199 KFGFDDAFNYKEESDLTAALKRCFPNGIDIYFENVGGKMLDAVLVNMNMHGRIAVCGMIS 258 +++++ L G+D+ ++ G+ DA L + GR G Sbjct: 391 HLASSRTCDFEQQF-----LGATGGRGVDVVLNSLAGEFADASLRMLPRGGRFLELG--- 442 Query: 259 QYNLENQEGVHNLSNIIYKRIRIQGFVVSDFYDKYSKFLEFVLPHIREGKITYVEDV-AD 317 + ++ + V + + + Q F + + + L + EG++ V A Sbjct: 443 KTDVRDPVEVAD----AHPGVSYQAFDTVEAGPQRIGEMLHELVELFEGRVLEPLPVTAW 498 Query: 318 GLEKAPEALVGLFHGKNVGKQVVVV 342 + +APEAL L ++VGK V+ + Sbjct: 499 DVRQAPEALRHLSQARHVGKLVLTM 523 >1QOR-A nrPDB Length = 327 Score = 42.0 bits (97), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 40/156 (25%), Positives = 68/156 (43%), Gaps = 12/156 (7%) Query: 138 MPGMTAYAGFYEVCSPKEGETVYVSAASGAVGQLVGQLAKMMGCYVVGSAGSKEKVDLLK 197 + G+T Y + K E AA+G VG + Q AK +G ++G+ G+ +K Sbjct: 123 LKGLTVYYLLRKTYEIKPDEQFLFHAAAGGVGLIACQWAKALGAKLIGTVGTAQKAQ-SA 181 Query: 198 TKFGFDDAFNYKEESDLTAALKRCF-PNGIDIYFENVGGKMLDAVLVNMNMHGRIA---- 252 K G NY+EE DL LK + + +++VG + L + G + Sbjct: 182 LKAGAWQVINYREE-DLVERLKEITGGKKVRVVYDSVGRDTWERSLDCLQRRGLMVSFGN 240 Query: 253 VCGMISQYNLENQEGVHNLSNIIY-KRIRIQGFVVS 287 G ++ NL G+ N +Y R +QG++ + Sbjct: 241 SSGAVTGVNL----GILNQKGSLYVTRPSLQGYITT 272 >4J6F-A nrPDB Length = 382 Score = 41.2 bits (95), Expect = 7e-04, Method: Compositional matrix adjust. Identities = 31/104 (29%), Positives = 49/104 (47%), Gaps = 4/104 (3%) Query: 156 GETVYVSAASGAVGQLVGQLAKMMGCYVVGSAGSKEKVDLLKTKFGFDDAFNYKEESDLT 215 GETV V+ ASG VG + QLA+ G + AG ++ +L A + + DL Sbjct: 207 GETVLVTGASGGVGSAIIQLARARGAVPIAVAGPGKEAAMLDIGA---QAVVTRGQGDLA 263 Query: 216 AALKRCF-PNGIDIYFENVGGKMLDAVLVNMNMHGRIAVCGMIS 258 A++ ID+ + VGG + + +L + GR G I+ Sbjct: 264 EAVEAASGGRPIDVVADLVGGPLFNDLLKILRPEGRYTTAGAIA 307 >5ENV-A nrPDB Length = 347 Score = 40.4 bits (93), Expect = 0.001, Method: Compositional matrix adjust. Identities = 58/237 (24%), Positives = 104/237 (43%), Gaps = 18/237 (7%) Query: 105 AWEEYSVITPMTHAHFKIQHTDVPLSYYTGLLGMPGMTAYAGFYEVCSPKEGETVYVSAA 164 ++++Y+ + AH Q TD L+ +L G+T Y + + G V +S A Sbjct: 124 SFQQYATADAVQAAHIP-QGTD--LAQVAPIL-CAGITVYKAL-KSANLMAGHWVAISGA 178 Query: 165 SGAVGQLVGQLAKMMGCYVVGSAGSKEKVDLLKTKFGFDDAFNYKEESDLTAALKRCFPN 224 +G +G L Q AK MG V+G G + K +L ++ G + ++ +E D+ A+ + Sbjct: 179 AGGLGSLAVQYAKAMGYRVLGIDGGEGKEELFRS-IGGEVFIDFTKEKDIVGAVLKATDG 237 Query: 225 GID-IYFENVGGKMLDAVLVNMNMHGRIAVCGMISQYNLENQEGVHNLSNIIYKRIRIQG 283 G + +V ++A + +G + GM + + ++ N + K I I G Sbjct: 238 GAHGVINVSVSEAAIEASTRYVRANGTTVLVGMPA-----GAKCCSDVFNQVVKSISIVG 292 Query: 284 FVVSDFYDKYSKFLEFVLPHIREGKITYVEDVADGLEKAPEALVGLFHGKNVGKQVV 340 V + D + L+F + + I V GL PE + G+ VG+ VV Sbjct: 293 SYVGNRADT-REALDFFARGLVKSPIKVV-----GLSTLPEIYEKMEKGQIVGRYVV 343 >2DFV-A nrPDB Length = 347 Score = 37.7 bits (86), Expect = 0.006, Method: Compositional matrix adjust. Identities = 43/154 (27%), Positives = 73/154 (47%), Gaps = 12/154 (7%) Query: 150 VCSPKEGETVYVSAASGAVGQLVGQLAKMMGCY-VVGSAGSKEKVDLLKTKFGFDDAFNY 208 + P G++V ++ A G +G L +AK G Y V+ S S + +L K K G D N Sbjct: 161 LAGPISGKSVLITGA-GPLGLLGIAVAKASGAYPVIVSEPSDFRRELAK-KVGADYVINP 218 Query: 209 KEESDLTAALKRCFPNGIDIYFENVGG-KMLDAVLVNMNMHGRIAVCGMISQYNLENQEG 267 EE + + NG+D++ E G K L+ L + GR+++ G+ Y + Sbjct: 219 FEEDVVKEVMDITDGNGVDVFLEFSGAPKALEQGLQAVTPAGRVSLLGL---YPGKVTID 275 Query: 268 VHNLSNIIYKRIRIQGFVVSDFYDKY---SKFLE 298 +NL II+K + I G ++ + S+ L+ Sbjct: 276 FNNL--IIFKALTIYGITGRHLWETWYTVSRLLQ 307 >3JYN-A nrPDB Length = 325 Score = 37.4 bits (85), Expect = 0.009, Method: Compositional matrix adjust. Identities = 35/134 (26%), Positives = 55/134 (41%), Gaps = 3/134 (2%) Query: 79 QGYGVSRIIESGHPDYKKGD-LLWGIVAWEEYSVITPMTHAHFKIQHTDVPLSYYTGLLG 137 +G GV + +K GD + +G YS + + A+ V L+ Sbjct: 64 EGAGVVEAVGDEVTRFKVGDRVAYGTGPLGAYSEVHVLPEANLVKLADSVSFEQAAALM- 122 Query: 138 MPGMTAYAGFYEVCSPKEGETVYVSAASGAVGQLVGQLAKMMGCYVVGSAGSKEKVDLLK 197 + G+T + K GE + AA+G VG L Q AK +G ++G+ S EK K Sbjct: 123 LKGLTVQYLLRQTYQVKPGEIILFHAAAGGVGSLACQWAKALGAKLIGTVSSPEKAAHAK 182 Query: 198 TKFGFDDAFNYKEE 211 G + +Y E Sbjct: 183 A-LGAWETIDYSHE 195 >3HZZ-A nrPDB Length = 467 Score = 32.3 bits (72), Expect = 0.27, Method: Compositional matrix adjust. Identities = 34/146 (23%), Positives = 53/146 (36%), Gaps = 21/146 (14%) Query: 139 PGMTAYAGFYEVCSP-----KEGETVYVSAASGAVGQLVGQLAKMMGCYVVGSAGSKEKV 193 PG+ + ++ S K+G+ V + ASG +G Q A G + S +K Sbjct: 225 PGLVNSTAYRQLVSRNGAAMKQGDNVLIWGASGGLGSYATQFALAGGANPICVVSSPQKA 284 Query: 194 DLLKT--------------KFGFDDAFNYKEESDLTAALKRCFPNG--IDIYFENVGGKM 237 ++ ++ KF D+ +E R G IDI FE+ G + Sbjct: 285 EICRSMGAEAIIDRNAEGYKFWKDEHTQDPKEWKRFGKRIRELTGGEDIDIVFEHPGRET 344 Query: 238 LDAVLVNMNMHGRIAVCGMISQYNLE 263 A + G I C S Y E Sbjct: 345 FGASVYVTRKGGTITTCASTSGYMHE 370 >4EYE-A nrPDB Length = 342 Score = 32.3 bits (72), Expect = 0.31, Method: Compositional matrix adjust. Identities = 29/102 (28%), Positives = 45/102 (44%), Gaps = 2/102 (1%) Query: 154 KEGETVYVSAASGAVGQLVGQLAKMMGCYVVGSAGSKEKVDLLKTKFGFDDAFNYKEESD 213 + GETV V A+G +G Q+AK MG V+ + +K+ G D EE Sbjct: 158 RAGETVLVLGAAGGIGTAAIQIAKGMGAKVIAVVNRTAATEFVKS-VGADIVLPL-EEGW 215 Query: 214 LTAALKRCFPNGIDIYFENVGGKMLDAVLVNMNMHGRIAVCG 255 A + G+D+ + +GG D + + GR+ V G Sbjct: 216 AKAVREATGGAGVDMVVDPIGGPAFDDAVRTLASEGRLLVVG 257 >4PVC-A nrPDB Length = 342 Score = 32.3 bits (72), Expect = 0.33, Method: Compositional matrix adjust. Identities = 19/58 (32%), Positives = 32/58 (55%) Query: 158 TVYVSAASGAVGQLVGQLAKMMGCYVVGSAGSKEKVDLLKTKFGFDDAFNYKEESDLT 215 +V+VS A+G + Q + L V+GSA S+EK + L FG + F+ + D++ Sbjct: 2 SVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDIS 59 >3RSH-A nrPDB Length = 251 Score = 32.0 bits (71), Expect = 0.37, Method: Compositional matrix adjust. Identities = 23/85 (27%), Positives = 36/85 (42%), Gaps = 5/85 (5%) Query: 155 EGETVYVSAASGAVGQLVGQLAKMMGCYVVGSAGSKEKVDLLKTKFGFDD---AFNYKEE 211 EG+ V+ AS +G+ + +L G V+G+A S+ + G + A N Sbjct: 11 EGKVALVTGASRGIGKAIAELLAERGAKVIGTATSESGAQAISDYLGDNGKGMALNVTNP 70 Query: 212 SDLTAALKRCFPN--GIDIYFENVG 234 + A LK G+DI N G Sbjct: 71 ESIEAVLKAITDEFGGVDILVNNAG 95 >5B6K-A nrPDB Length = 366 Score = 32.0 bits (71), Expect = 0.43, Method: Compositional matrix adjust. Identities = 29/85 (34%), Positives = 38/85 (44%), Gaps = 7/85 (8%) Query: 158 TVYVSAASGAVGQLVGQLAKMMGCYVVGSAGSKEKVDLLKTKFGFDDAFNYKEESDLTAA 217 TV+VS A+G + Q V + V+GS S EK D LK FNY+ D++ Sbjct: 23 TVFVSGATGFIAQHVVRQLLDQNYKVIGSVRSAEKGDHLKNVIFKGGDFNYEIVKDISD- 81 Query: 218 LKRCFPNGIDIYFENVGGKMLDAVL 242 P D FE GK + VL Sbjct: 82 -----PTAFDHVFEK-HGKDIKVVL 100 >1WZA-A nrPDB Length = 488 Score = 31.6 bits (70), Expect = 0.50, Method: Compositional matrix adjust. Identities = 23/87 (26%), Positives = 37/87 (42%), Gaps = 9/87 (10%) Query: 174 QLAKMMGCYVVGSAGSKEKVDLLKTKFGFDDAFNYKEESDLTAALKRCFPNGID------ 227 ++ ++ Y+VG + K+GFD FN+K + A K FP G + Sbjct: 221 EIEEVKPVYLVGEVWDISETVAPYFKYGFDSTFNFKLAEAVIATAKAGFPFGFNKKAKHI 280 Query: 228 --IYFENVG-GKMLDAVLVNMNMHGRI 251 +Y VG G +DA + + RI Sbjct: 281 YGVYDREVGFGNYIDAPFLTNHDQNRI 307 >5YWN-A nrPDB Length = 334 Score = 31.2 bits (69), Expect = 0.72, Method: Compositional matrix adjust. Identities = 21/52 (40%), Positives = 30/52 (57%), Gaps = 2/52 (3%) Query: 158 TVYVSAASGAVGQLVGQLAKMMGCYVVGSAGSKEKVDLLKTKFGFDDAFNYK 209 +V+VS A+G + Q + L G VVGS S+EK LK +G D F+Y+ Sbjct: 4 SVFVSGATGYLAQQIIALVLSKGYKVVGSVRSEEKGANLKKLYG--DDFSYE 53 >3DAF-A nrPDB Length = 358 Score = 30.4 bits (67), Expect = 1.1, Method: Compositional matrix adjust. Identities = 24/70 (34%), Positives = 33/70 (47%), Gaps = 11/70 (15%) Query: 283 GFVVSDFYDK-------YSKFLEFVLPHIREGKITYVEDVADGLEKAPEALVGLFHGKNV 335 G VV D +D S E ++P IRE V+ A L K P+A + L H ++V Sbjct: 72 GLVVIDEFDPKEVMEAHLSGNPESIMPKIRE----VVKAKAKELPKPPKACIHLVHPEDV 127 Query: 336 GKQVVVVARE 345 G +V RE Sbjct: 128 GLKVTSDDRE 137 >4IDE-A nrPDB Length = 332 Score = 30.4 bits (67), Expect = 1.3, Method: Compositional matrix adjust. Identities = 23/64 (35%), Positives = 34/64 (53%), Gaps = 12/64 (18%) Query: 174 QLAK-MMGCYVVGSAGSKEKVDLLKTKFGFDDAFNYKEES--DLTAALKRCFPNGIDIYF 230 QLAK + G V + S +K+DLL+T G D A +Y +E+ DL P D+ + Sbjct: 192 QLAKHVFGASKVAATASTKKLDLLRT-LGADLAIDYTKENFEDL--------PEKFDVVY 242 Query: 231 ENVG 234 + VG Sbjct: 243 DAVG 246 >4RJ9-A nrPDB Length = 165 Score = 29.6 bits (65), Expect = 2.0, Method: Compositional matrix adjust. Identities = 17/45 (37%), Positives = 26/45 (57%), Gaps = 2/45 (4%) Query: 30 VELRVPEGTNSVLVKNLYLSCDPYMRIRMGKPDPSTAALAQAYTP 74 V++RV G N + V++L S DPY+ +RMGK T + + P Sbjct: 9 VKVRVVRGVN-LAVRDLR-SSDPYVIVRMGKQKLKTRVIKKTTNP 51 >4A10-A nrPDB Length = 447 Score = 28.1 bits (61), Expect = 6.0, Method: Compositional matrix adjust. Identities = 30/124 (24%), Positives = 43/124 (34%), Gaps = 18/124 (14%) Query: 154 KEGETVYVSAASGAVGQLVGQLAKMMGCYVVGSAGSKEKVDLLKTKFGFDDAFNYKE--- 210 K+G+ V + ASG +G Q K G V S +K ++ G D N E Sbjct: 219 KQGDIVLIWGASGGLGSYAIQFVKNGGGIPVAVVSSAQKEAAVRA-LGCDLVINRAELGI 277 Query: 211 ESDLTAALKRCFPNGI--------------DIYFENVGGKMLDAVLVNMNMHGRIAVCGM 256 D+ +R G DI FE+ G ++ G + CG Sbjct: 278 TDDIADDPRRVVETGRKLAKLVVEKAGREPDIVFEHTGRVTFGLSVIVARRGGTVVTCGS 337 Query: 257 ISQY 260 S Y Sbjct: 338 SSGY 341 >5D6S-A nrPDB Length = 399 Score = 27.7 bits (60), Expect = 7.2, Method: Compositional matrix adjust. Identities = 20/63 (31%), Positives = 26/63 (41%), Gaps = 1/63 (1%) Query: 16 GFPTESDFDFTTTTVELRVPEG-TNSVLVKNLYLSCDPYMRIRMGKPDPSTAALAQAYTP 74 GF T DFD+ ++ L V EG T KN+ P + + K S A P Sbjct: 47 GFTTADDFDYLEKSLRLGVEEGRTTGFEHKNIEERIYPKLSLESAKTIISIAVAYPHKLP 106 Query: 75 GQP 77 QP Sbjct: 107 QQP 109 >6F3T-A nrPDB Length = 608 Score = 27.7 bits (60), Expect = 7.6, Method: Compositional matrix adjust. Identities = 18/72 (25%), Positives = 31/72 (43%), Gaps = 2/72 (2%) Query: 3 ATNKQVILKDYVSGFPTESDFDFTTTTVELRVPEGTNSVLVKNLYLSCDPYMRIRMGKPD 62 + + V L D + F DFTT T + +PE + +L+ P + + + + Sbjct: 538 SMDNTVRLWDAIKAFEDLETDDFTTATGHINLPENSQELLLGTYMTKSTPVVHLHFTRRN 597 Query: 63 PSTAALAQAYTP 74 A A AY+P Sbjct: 598 LVLA--AGAYSP 607 >3FPC-A nrPDB Length = 352 Score = 27.7 bits (60), Expect = 8.0, Method: Compositional matrix adjust. Identities = 34/152 (22%), Positives = 63/152 (41%), Gaps = 18/152 (11%) Query: 92 PDYKKGDLLWG--------IVAWEEYSVITPMTHAHFKIQHTDVPLSYY------TGLLG 137 PD++ ++ G + W+ +V + F + D+ L++ + Sbjct: 88 PDWRTSEVQRGYHQHSGGMLAGWKFSNVKDGVFGEFFHVNDADMNLAHLPKEIPLEAAVM 147 Query: 138 MPGMTAYAGFY--EVCSPKEGETVYVSAASGAVGQLVGQLAKMMGCYVVGSAGSKEKVDL 195 +P M GF+ E+ + K G+TV V G VG + A +G + + GS++ Sbjct: 148 IPDMMT-TGFHGAELANIKLGDTVCVIGI-GPVGLMSVAGANHLGAGRIFAVGSRKHCCD 205 Query: 196 LKTKFGFDDAFNYKEESDLTAALKRCFPNGID 227 + ++G D NYK + LK G+D Sbjct: 206 IALEYGATDIINYKNGDIVEQILKATDGKGVD 237 >2OUI-A nrPDB Length = 360 Score = 27.7 bits (60), Expect = 8.0, Method: Compositional matrix adjust. Identities = 24/84 (28%), Positives = 39/84 (46%), Gaps = 3/84 (3%) Query: 146 GFY--EVCSPKEGETVYVSAASGAVGQLVGQLAKMMGCYVVGSAGSKEKVDLLKTKFGFD 203 GF+ E+ + K G+TV V G VG + A +G + + GS++ + ++G Sbjct: 155 GFHGAELANIKLGDTVCVIGI-GPVGLMSVAGANHLGAGRIFAVGSRKHCCDIALEYGAT 213 Query: 204 DAFNYKEESDLTAALKRCFPNGID 227 D NYK + LK G+D Sbjct: 214 DIINYKNGDIVEQILKATDGKGVD 237 >6MZM-G nrPDB Length = 800 Score = 27.3 bits (59), Expect = 9.1, Method: Compositional matrix adjust. Identities = 18/72 (25%), Positives = 31/72 (43%), Gaps = 2/72 (2%) Query: 3 ATNKQVILKDYVSGFPTESDFDFTTTTVELRVPEGTNSVLVKNLYLSCDPYMRIRMGKPD 62 + + V L D + F DFTT T + +PE + +L+ P + + + + Sbjct: 730 SMDNTVRLWDAIKAFEDLETDDFTTATGHINLPENSQELLLGTYMTKSTPVVHLHFTRRN 789 Query: 63 PSTAALAQAYTP 74 A A AY+P Sbjct: 790 LVLA--AGAYSP 799 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 2J3K-A nrPDB 476 e-135 1V3V-A nrPDB 354 4e-98 2Y05-A nrPDB 345 1e-95 2VNA-A nrPDB 344 3e-95 2ZB3-A nrPDB 324 4e-89 2WEK-A nrPDB 205 2e-53 1YB5-A nrPDB 202 2e-52 2OBY-A nrPDB 186 8e-48 3UOG-A nrPDB 186 2e-47 2VCY-A nrPDB 181 2e-46 3SLK-A nrPDB 177 7e-45 4A27-A nrPDB 172 2e-43 1WLY-A nrPDB 168 2e-42 5A3V-A nrPDB 162 2e-40 1QOR-A nrPDB 161 3e-40 5ENV-A nrPDB 160 8e-40 3QWB-A nrPDB 158 3e-39 3TQH-A nrPDB 151 4e-37 4RVS-A nrPDB 145 2e-35 5K1S-A nrPDB 136 2e-32 4J6F-A nrPDB 127 9e-30 3FBG-A nrPDB 116 1e-26 1O89-A nrPDB 106 2e-23 Sequences not found previously or not previously below threshold: 3JYN-A nrPDB 144 3e-35 2VN8-A nrPDB 116 1e-26 4EYE-A nrPDB 114 5e-26 3PII-A nrPDB 108 3e-24 5YAT-A nrPDB 107 8e-24 5LB9-A nrPDB 105 2e-23 1LLU-A nrPDB 104 7e-23 3MEQ-A nrPDB 104 8e-23 2EER-A nrPDB 103 1e-22 3HZZ-A nrPDB 101 5e-22 6N7L-A nrPDB 98 4e-21 4Z6K-A nrPDB 98 7e-21 4EEZ-A nrPDB 95 4e-20 3S2F-A nrPDB 93 2e-19 4Y1B-A nrPDB 93 2e-19 4A10-A nrPDB 93 2e-19 4DVJ-A nrPDB 92 3e-19 4IDE-A nrPDB 92 4e-19 1H2B-A nrPDB 91 9e-19 1R37-A nrPDB 85 5e-17 4CPD-A nrPDB 81 6e-16 5GXF-A nrPDB 80 1e-15 2DFV-A nrPDB 79 2e-15 4GKV-A nrPDB 78 4e-15 3FPC-A nrPDB 77 1e-14 3GFB-A nrPDB 76 1e-14 4OH1-A nrPDB 76 2e-14 5VM2-A nrPDB 75 5e-14 3FSR-A nrPDB 73 2e-13 1HSO-A nrPDB 72 3e-13 3COS-A nrPDB 72 3e-13 4EJ6-A nrPDB 72 3e-13 5TNX-A nrPDB 71 5e-13 1KEV-A nrPDB 71 6e-13 1HSZ-A nrPDB 71 7e-13 1U3W-A nrPDB 71 1e-12 5KIA-A nrPDB 70 2e-12 2OUI-A nrPDB 69 2e-12 1UUF-A nrPDB 69 3e-12 1CDO-A nrPDB 66 2e-11 1P0F-A nrPDB 66 2e-11 1YKF-A nrPDB 66 2e-11 2H6E-A nrPDB 65 4e-11 4DLA-A nrPDB 65 5e-11 1Q1N-A nrPDB 64 6e-11 5YLN-A nrPDB 64 6e-11 1F8F-A nrPDB 64 7e-11 1EE2-A nrPDB 64 8e-11 4RQU-A nrPDB 64 8e-11 3FPL-A nrPDB 64 1e-10 4JJI-A nrPDB 63 1e-10 1MC5-A nrPDB 63 1e-10 6FG0-A nrPDB 63 2e-10 1D1T-A nrPDB 63 3e-10 3IP1-A nrPDB 60 1e-09 4UEJ-A nrPDB 60 1e-09 5FI5-A nrPDB 59 3e-09 1E3E-A nrPDB 56 3e-08 2CF5-A nrPDB 55 4e-08 1PL8-A nrPDB 54 9e-08 3RSH-A nrPDB 52 4e-07 3WLE-A nrPDB 50 1e-06 3TWO-A nrPDB 50 2e-06 1YQX-A nrPDB 49 3e-06 6DKH-A nrPDB 48 5e-06 6C49-A nrPDB 48 6e-06 3QE3-A nrPDB 48 9e-06 1Q7C-A nrPDB 48 9e-06 5Z0C-A nrPDB 46 3e-05 4OAQ-A nrPDB 45 5e-05 3D3W-A nrPDB 44 1e-04 3F9I-A nrPDB 43 3e-04 5CDY-A nrPDB 42 5e-04 5VKT-A nrPDB 41 8e-04 3EMK-A nrPDB 41 8e-04 4M8S-A nrPDB 39 0.002 3PWS-A nrPDB 39 0.003 5T5Q-A nrPDB 39 0.004 1BDB-A nrPDB 38 0.004 3PPI-A nrPDB 38 0.005 3GRP-A nrPDB 38 0.005 5E4R-A nrPDB 38 0.005 4XDZ-A nrPDB 38 0.006 3VZS-A nrPDB 38 0.009 4BO1-A nrPDB 37 0.013 3EZL-A nrPDB 37 0.016 3DWF-A nrPDB 36 0.024 2UVD-A nrPDB 36 0.024 5PGZ-A nrPDB 36 0.026 2DPH-A nrPDB 36 0.033 5YWN-A nrPDB 35 0.052 4PVC-A nrPDB 35 0.054 5YSS-A nrPDB 34 0.069 1ZZE-A nrPDB 34 0.076 5H83-A nrPDB 34 0.082 5B6K-A nrPDB 34 0.12 2Q2Q-A nrPDB 34 0.14 4HP8-A nrPDB 33 0.15 1YXM-A nrPDB 33 0.15 1AE1-A nrPDB 33 0.16 2PNF-A nrPDB 33 0.18 1KOL-A nrPDB 33 0.19 3L07-A nrPDB 33 0.23 1HXH-A nrPDB 33 0.26 4JLW-A nrPDB 33 0.27 3UF0-A nrPDB 33 0.27 4CQM-B nrPDB 33 0.29 1OOE-A nrPDB 33 0.29 3LYL-A nrPDB 33 0.29 4FHN-X nrPDB 33 0.30 3ZV3-A nrPDB 32 0.33 1CYD-A nrPDB 32 0.33 2B4Q-A nrPDB 32 0.36 1E3W-A nrPDB 32 0.39 2ZAT-A nrPDB 32 0.42 3C3P-A nrPDB 32 0.43 3RWB-A nrPDB 32 0.46 4IIN-A nrPDB 32 0.46 2YFH-A nrPDB 31 0.55 5ILO-A nrPDB 31 0.65 3X43-A nrPDB 31 0.69 3GDF-A nrPDB 31 0.78 2R6H-A nrPDB 31 0.80 6EOT-A nrPDB 31 0.82 6DLL-A nrPDB 31 0.82 5TQV-A nrPDB 31 0.87 5JJC-A nrPDB 31 0.91 2CDH-G nrPDB 31 0.95 5ITV-A nrPDB 31 0.97 1YS4-A nrPDB 31 1.1 4DBZ-A nrPDB 30 1.2 1NPY-A nrPDB 30 1.2 4AVY-A nrPDB 30 1.4 5IJZ-A nrPDB 30 1.4 2C07-A nrPDB 30 1.7 3D2A-A nrPDB 30 1.8 3W8F-A nrPDB 30 1.8 4ZZA-A nrPDB 30 1.9 1O5I-A nrPDB 30 1.9 4R1T-A nrPDB 29 2.1 6DTT-A nrPDB 29 2.4 5TC4-A nrPDB 29 2.4 1DIR-A nrPDB 29 2.4 4B4O-A nrPDB 29 2.6 1URG-A nrPDB 29 2.8 1DOH-A nrPDB 29 2.8 3OML-A nrPDB 29 2.9 1W1U-A nrPDB 29 3.1 3O4R-A nrPDB 29 3.3 6MDV-A nrPDB 29 3.6 4MOW-A nrPDB 29 3.8 4R1U-A nrPDB 29 3.9 2PTG-A nrPDB 29 4.0 2JC3-A nrPDB 29 4.1 2BHS-A nrPDB 29 4.3 2VHY-A nrPDB 28 5.6 1UZM-A nrPDB 28 6.2 2HSD-A nrPDB 28 7.6 5HPZ-A nrPDB 28 7.7 1X1T-A nrPDB 27 7.8 4EJ0-A nrPDB 27 8.3 >2J3K-A nrPDB Length = 345 Score = 476 bits (1224), Expect = e-135, Method: Composition-based stats. Identities = 344/345 (99%), Positives = 344/345 (99%) Query: 1 MTATNKQVILKDYVSGFPTESDFDFTTTTVELRVPEGTNSVLVKNLYLSCDPYMRIRMGK 60 MTATNKQVILKDYVSGFPTESDFDFTTTTVELRVPEGTNSVLVKNLYLSCDPYMRIRMGK Sbjct: 1 MTATNKQVILKDYVSGFPTESDFDFTTTTVELRVPEGTNSVLVKNLYLSCDPYMRIRMGK 60 Query: 61 PDPSTAALAQAYTPGQPIQGYGVSRIIESGHPDYKKGDLLWGIVAWEEYSVITPMTHAHF 120 PDPSTAALAQAYTPGQPIQGYGVSRIIESGHPDYKKGDLLWGIVAWEEYSVITPMTHAHF Sbjct: 61 PDPSTAALAQAYTPGQPIQGYGVSRIIESGHPDYKKGDLLWGIVAWEEYSVITPMTHAHF 120 Query: 121 KIQHTDVPLSYYTGLLGMPGMTAYAGFYEVCSPKEGETVYVSAASGAVGQLVGQLAKMMG 180 KIQHTDVPLSYYTGLLGMPGMTAYAGFYEVCSPKEGETVYVSAASGAVGQLVGQLAKMMG Sbjct: 121 KIQHTDVPLSYYTGLLGMPGMTAYAGFYEVCSPKEGETVYVSAASGAVGQLVGQLAKMMG 180 Query: 181 CYVVGSAGSKEKVDLLKTKFGFDDAFNYKEESDLTAALKRCFPNGIDIYFENVGGKMLDA 240 CYVVGSAGSKEKVDLLKTKFGFDDAFNYKEESDLTAALKRCFPNGIDIYFENVGGKMLDA Sbjct: 181 CYVVGSAGSKEKVDLLKTKFGFDDAFNYKEESDLTAALKRCFPNGIDIYFENVGGKMLDA 240 Query: 241 VLVNMNMHGRIAVCGMISQYNLENQEGVHNLSNIIYKRIRIQGFVVSDFYDKYSKFLEFV 300 VLVNMNMHGRIAVCGMISQYNLENQEGVHNLSNIIYKR RIQGFVVSDFYDKYSKFLEFV Sbjct: 241 VLVNMNMHGRIAVCGMISQYNLENQEGVHNLSNIIYKRNRIQGFVVSDFYDKYSKFLEFV 300 Query: 301 LPHIREGKITYVEDVADGLEKAPEALVGLFHGKNVGKQVVVVARE 345 LPHIREGKITYVEDVADGLEKAPEALVGLFHGKNVGKQVVVVARE Sbjct: 301 LPHIREGKITYVEDVADGLEKAPEALVGLFHGKNVGKQVVVVARE 345 >1V3V-A nrPDB Length = 333 Score = 354 bits (907), Expect = 4e-98, Method: Composition-based stats. Identities = 140/339 (41%), Positives = 193/339 (56%), Gaps = 18/339 (5%) Query: 6 KQVILKDYVSGFPTESDFDFTTTTVELRVPEGTNSVLVKNLYLSCDPYMRIRMGKPDPST 65 K LK + G PT+SDF+ T + P VL++ L+LS DPYMRI Sbjct: 9 KSWTLKKHFQGKPTQSDFELKTVELP---PLKNGEVLLEALFLSVDPYMRIA-------- 57 Query: 66 AALAQAYTPGQPIQGYGVSRIIESGHPDYKKGDLLWGIVAWEEYSVITPMTHAHFKIQHT 125 ++ G + G V+R++ES + + G ++ W + + + Sbjct: 58 ---SKRLKEGAVMMGQQVARVVESKNSAFPAGSIVLAQSGWTTHFISDGKGLEKLLTEWP 114 Query: 126 D-VPLSYYTGLLGMPGMTAYAGFYEVCSPKEGETVYVSAASGAVGQLVGQLAKMMGCYVV 184 D +PLS G +GMPG+TAY G EVC K GETV VSAA+GAVG +VGQ+AK+ GC VV Sbjct: 115 DKLPLSLALGTIGMPGLTAYFGLLEVCGVKGGETVLVSAAAGAVGSVVGQIAKLKGCKVV 174 Query: 185 GSAGSKEKVDLLKTKFGFDDAFNYKEESDLTAALKRCFPNGIDIYFENVGGKMLDAVLVN 244 G+AGS EK+ LK + GFD AFNYK + L ALK+ P+G D YF+NVGG+ L+ VL Sbjct: 175 GAAGSDEKIAYLK-QIGFDAAFNYKTVNSLEEALKKASPDGYDCYFDNVGGEFLNTVLSQ 233 Query: 245 MNMHGRIAVCGMISQYNLENQ-EGVHNLSNIIYKRIRIQGFVVSDFY-DKYSKFLEFVLP 302 M G+IA+CG IS YN +Q + +IIYK++RI+GF+V + D K L ++ Sbjct: 234 MKDFGKIAICGAISVYNRMDQLPPGPSPESIIYKQLRIEGFIVYRWQGDVREKALRDLMK 293 Query: 303 HIREGKITYVEDVADGLEKAPEALVGLFHGKNVGKQVVV 341 + EGKI Y E V G E P A + + +G N+GK VV Sbjct: 294 WVLEGKIQYHEHVTKGFENMPAAFIEMLNGANLGKAVVT 332 >2Y05-A nrPDB Length = 328 Score = 345 bits (885), Expect = 1e-95, Method: Composition-based stats. Identities = 132/341 (38%), Positives = 187/341 (54%), Gaps = 18/341 (5%) Query: 3 ATNKQVILKDYVSGFPTESDFDFTTTTVELRVPEGTNSVLVKNLYLSCDPYMRIRMGKPD 62 + K LK + G+PT SDF+ T+ + P VL++ L+L+ DPYMR+ Sbjct: 1 SMTKTWTLKKHFVGYPTNSDFELKTSELP---PLKNGEVLLEALFLTVDPYMRVA----- 52 Query: 63 PSTAALAQAYTPGQPIQGYGVSRIIESGHPDYKKGDLLWGIVAWEEYSVITPMTHAHFKI 122 A+ G + G V++++ES + KG ++ W +S+ Sbjct: 53 ------AKRLKEGDTMMGQQVAKVVESKNVALPKGTIVLASPGWTTHSISDGKDLEKLLT 106 Query: 123 QHTD-VPLSYYTGLLGMPGMTAYAGFYEVCSPKEGETVYVSAASGAVGQLVGQLAKMMGC 181 + D +PLS G +GMPG+TAY G E+C K GETV V+AA+GAVG +VGQ+AK+ GC Sbjct: 107 EWPDTIPLSLALGTVGMPGLTAYFGLLEICGVKGGETVMVNAAAGAVGSVVGQIAKLKGC 166 Query: 182 YVVGSAGSKEKVDLLKTKFGFDDAFNYKEESDLTAALKRCFPNGIDIYFENVGGKMLDAV 241 VVG+ GS EKV L+ K GFD FNYK L LK+ P+G D YF+NVGG+ + V Sbjct: 167 KVVGAVGSDEKVAYLQ-KLGFDVVFNYKTVESLEETLKKASPDGYDCYFDNVGGEFSNTV 225 Query: 242 LVNMNMHGRIAVCGMISQYNLENQEGVHNLSNI-IYKRIRIQGFVVSDFY-DKYSKFLEF 299 + M GRIA+CG IS YN I IY+ +R++ FVV + D K L+ Sbjct: 226 IGQMKKFGRIAICGAISTYNRTGPLPPGPPPEIVIYQELRMEAFVVYRWQGDARQKALKD 285 Query: 300 VLPHIREGKITYVEDVADGLEKAPEALVGLFHGKNVGKQVV 340 +L + EGKI Y E + +G E P A +G+ G N+GK +V Sbjct: 286 LLKWVLEGKIQYKEYIIEGFENMPAAFMGMLKGDNLGKTIV 326 >2VNA-A nrPDB Length = 357 Score = 344 bits (883), Expect = 3e-95, Method: Composition-based stats. Identities = 114/339 (33%), Positives = 172/339 (50%), Gaps = 13/339 (3%) Query: 15 SGFPTESDFDFTTTTVELRVPEGTNSVLVKNLYLSCDPYMRIRMGKPDPSTAALAQAYTP 74 +G P +F + + EG V V+ LYLS DPYMR RM + D T + + Sbjct: 16 NGNPVAENFRMEEVYLPDNINEG--QVQVRTLYLSVDPYMRCRMNE-DTGTDYIT-PWQL 71 Query: 75 GQPIQGYGVSRIIESGHPDYKKGDLLWGIV-AWEEYSVITPMTHAHFKIQHTDVPLSYYT 133 Q + G G+ I ES H + KGD + W+ ++ + Q D LSY+ Sbjct: 72 SQVVDGGGIGIIEESKHTNLTKGDFVTSFYWPWQTKVILDGNSLEKVDPQLVDGHLSYFL 131 Query: 134 GLLGMPGMTAYAGFYEVCSPKEG--ETVYVSAASGAVGQLVGQLAKMMGC-YVVGSAGSK 190 G +GMPG+T+ G E G +T+ VS A+GA G + GQ+ +GC VVG G+ Sbjct: 132 GAIGMPGLTSLIGIQEKGHITAGSNKTMVVSGAAGACGSVAGQIGHFLGCSRVVGICGTH 191 Query: 191 EKVDLLKTKFGFDDAFNYKEESDLTAALKRCFPNGIDIYFENVGGKMLDAVLVNMNMHGR 250 EK LL ++ GFD A NYK+ ++ L+ P G+D+YF+NVGG + D V+ MN + Sbjct: 192 EKCILLTSELGFDAAINYKK-DNVAEQLRESCPAGVDVYFDNVGGNISDTVISQMNENSH 250 Query: 251 IAVCGMISQYNLE----NQEGVHNLSNIIYKRIRIQGFVVSDFYDKYSKFLEFVLPHIRE 306 I +CG ISQYN + + + I + F+V ++ DK+ + + +E Sbjct: 251 IILCGQISQYNKDVPYPPPLSPAIEAIQKERNITRERFLVLNYKDKFEPGILQLSQWFKE 310 Query: 307 GKITYVEDVADGLEKAPEALVGLFHGKNVGKQVVVVARE 345 GK+ E V +GLE A + G N+GKQ+V ++ E Sbjct: 311 GKLKIKETVINGLENMGAAFQSMMTGGNIGKQIVCISEE 349 >2ZB3-A nrPDB Length = 353 Score = 324 bits (829), Expect = 4e-89, Method: Composition-based stats. Identities = 115/344 (33%), Positives = 173/344 (50%), Gaps = 23/344 (6%) Query: 15 SGFPTESDFDFTTTTVELRVPEGTNSVLVKNLYLSCDPYMRIRMGKPDPSTAALAQAYTP 74 +G +F ++ + EG V V+ LYLS DPYMR +M + D T LA + Sbjct: 17 NGNTVAENFRVEEFSLPDALNEG--QVQVRTLYLSVDPYMRCKMNE-DTGTDYLA-PWQL 72 Query: 75 GQPIQGYGVSRIIESGHPDYKKGDLLWGIV-AWEEYSVITPMTHAHFKIQHTDVPLSYYT 133 Q G G+ + ES H KGD + W+ +++ Q D LSY+ Sbjct: 73 AQVADGGGIGVVEESKHQKLTKGDFVTSFYWPWQTKAILDGNGLEKVDPQLVDGHLSYFL 132 Query: 134 GLLGMPGMTAYAGFYEVCSPKEG--ETVYVSAASGAVGQLVGQLAKMMGC-YVVGSAGSK 190 G +GMPG+T+ G E G +T+ VS A+GA G L GQ+ ++GC VVG G++ Sbjct: 133 GAIGMPGLTSLIGVQEKGHISAGSNQTMVVSGAAGACGSLAGQIGHLLGCSRVVGICGTQ 192 Query: 191 EKVDLLKTKFGFDDAFNYKEESDLTAALKRCFPNGIDIYFENVGGKMLDAVLVNMNMHGR 250 EK L ++ GFD A NYK ++ L+ P G+D+YF+NVGG + +AV+ MN + Sbjct: 193 EKCLFLTSELGFDAAVNYKT-GNVAEQLREACPGGVDVYFDNVGGDISNAVISQMNENSH 251 Query: 251 IAVCGMISQYNLE---------NQEGVHNLSNIIYKRIRIQGFVVSDFYDKYSKFLEFVL 301 I +CG ISQY+ + E + NI +R F V ++ DK+ + + Sbjct: 252 IILCGQISQYSNDVPYPPPLPPAVEAIRKERNITRER-----FTVLNYKDKFEPGILQLS 306 Query: 302 PHIREGKITYVEDVADGLEKAPEALVGLFHGKNVGKQVVVVARE 345 +EGK+ E +A GLE A + G NVGKQ+V ++ + Sbjct: 307 QWFKEGKLKVKETMAKGLENMGVAFQSMMTGGNVGKQIVCISED 350 >2WEK-A nrPDB Length = 341 Score = 205 bits (522), Expect = 2e-53, Method: Composition-based stats. Identities = 93/328 (28%), Positives = 145/328 (44%), Gaps = 34/328 (10%) Query: 31 ELRVPEGTNSVLVKNLYLSCDPY-MRIRMGKPDPSTAALAQAYTPGQPIQGYGVSRIIES 89 + +P G +LV+N ++ + + G+ DPS P I G+ ++ Sbjct: 26 PVPLP-GDGDLLVRNRFVGVNASDINYSAGRYDPSV-------KPPFDIGFEGIGEVVAL 77 Query: 90 GHPD---YKKGDLL--WGIVAWEEYSVITPMTHAHFKIQHTDVPLSYYTGLLGMPGMTAY 144 G Y G + ++ EY+V+ A V Y L + G TAY Sbjct: 78 GLSASARYTVGQAVAYMAPGSFAEYTVV----PASIATPVPSVKPEYL--TLLVSGTTAY 131 Query: 145 AGFYEVCSPKEGETVYVSAASGAVGQLVGQLAKMMGCYVVGSAGSKEKVDLLKTKFGFDD 204 E+ EG+ V V+AA+G GQ QL+K C+V+G+ S EK LK+ G D Sbjct: 132 ISLKELGGLSEGKKVLVTAAAGGTGQFAMQLSKKAKCHVIGTCSSDEKSAFLKS-LGCDR 190 Query: 205 AFNYKEESDLTAALKRCFPNGIDIYFENVGGKMLDAVLVNMNMHGRIAVCGMISQYN--- 261 NYK E + LK+ +P G+D+ +E+VGG M D + + GR+ V G IS Y Sbjct: 191 PINYKTEP-VGTVLKQEYPEGVDVVYESVGGAMFDLAVDALATKGRLIVIGFISGYQTPT 249 Query: 262 -LENQEGVHNLSNIIYKRIRIQGFVVSDFYDKYSKFLEFVLPHIREGKITYVEDVAD--- 317 L + + ++ K +QGF ++ + KY + +L G + D+ D Sbjct: 250 GLSPVKAGTLPAKLLKKSASVQGFFLNHYLSKYQAAMSHLLEMCVSGDLVCEVDLGDLSP 309 Query: 318 -----GLEKAPEALVGLFHGKNVGKQVV 340 GLE A+ ++ GKN GK VV Sbjct: 310 EGRFTGLESIFRAVNYMYMGKNTGKIVV 337 >1YB5-A nrPDB Length = 351 Score = 202 bits (513), Expect = 2e-52, Method: Composition-based stats. Identities = 79/327 (24%), Positives = 138/327 (42%), Gaps = 35/327 (10%) Query: 28 TTVELRVPEGTNSVLVKNLYLSCDP---YMRIRMGKPDPSTAALAQAYTPGQPIQGYGVS 84 + + + +P + VL+K +P Y+R P YTPG + G V Sbjct: 48 SDIAVPIP-KDHQVLIKVHACGVNPVETYIRSGTYSRKPLL-----PYTPGSDVAG--VI 99 Query: 85 RIIESGHPDYKKGDLLWGIV----AWEEYSVITPMTHAHFKIQHTDVPLSYYTGL-LGMP 139 + +KKGD ++ + EY++ H +K+ L + G +G+P Sbjct: 100 EAVGDNASAFKKGDRVFTSSTISGGYAEYAL--AADHTVYKLPEK---LDFKQGAAIGIP 154 Query: 140 GMTAYAGFYEVCSPKEGETVYVSAASGAVGQLVGQLAKMMGCYVVGSAGSKEKVDLLKTK 199 TAY K GE+V V ASG VG Q+A+ G ++G+AG++E ++ + Sbjct: 155 YFTAYRALIHSACVKAGESVLVHGASGGVGLAACQIARAYGLKILGTAGTEEGQKIV-LQ 213 Query: 200 FGFDDAFNYKEESDLTAALKRCFPNGIDIYFENVGGKMLDAVLVNMNMHGRIAVCGMISQ 259 G + FN++E + + K GIDI E + L L ++ GR+ V G Sbjct: 214 NGAHEVFNHREVNYIDKIKKYVGEKGIDIIIEMLANVNLSKDLSLLSHGGRVIVVGSRGT 273 Query: 260 YNLENQEGVHNLSNIIYKRIRIQGFVVSDFYDKYSKFLEFVLPHIREGKITYVEDVA--- 316 + ++ + S+II V+ F +F ++ +I +++ V Sbjct: 274 IEINPRDTMAKESSIIG---------VTLFSSTKEEFQQYAAALQAGMEIGWLKPVIGSQ 324 Query: 317 DGLEKAPEALVGLFHGKN-VGKQVVVV 342 LEK EA + HG GK ++++ Sbjct: 325 YPLEKVAEAHENIIHGSGATGKMILLL 351 >2OBY-A nrPDB Length = 338 Score = 186 bits (473), Expect = 8e-48, Method: Composition-based stats. Identities = 65/297 (21%), Positives = 123/297 (41%), Gaps = 24/297 (8%) Query: 66 AALAQAYTPGQPIQGYG-VSRIIESGHPD---------YKKGDLLWGIVAWEEYSVITPM 115 A L Q P G + + SGH +K GD ++ + + Sbjct: 48 ADLMQRQGQYDPPPGASNILGLEASGHVAELGPGCQGHWKIGDTAMALLPGGGQAQYVTV 107 Query: 116 THAHFKIQHTDVPLSYYTGLLGMPGMTAYAGFYEVCSPKEGETVYVSAASGAVGQLVGQL 175 + L+ + +TA+ + V + + G+ V + A VG QL Sbjct: 108 PEGLLMPIPEGLTLTQAAA-IPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQL 166 Query: 176 AKMMGCYVVGSAGSKEKVDLLKTKFGFDDAFNYKEESDLTAALKRCFPNGIDIYFENVGG 235 +M G + +AGS++K+ + + K G FNYK+E A LK G+++ + +GG Sbjct: 167 TRMAGAIPLVTAGSQKKLQMAE-KLGAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIGG 225 Query: 236 KMLDAVLVNMNMHGRIAVCGMISQYNLENQEGVHNLSNIIYKRIRIQGFVVSDFYDKYSK 295 + + + + GR + G++ ++ S +++KR + ++ +KY + Sbjct: 226 SYWEKNVNCLALDGRWVLYGLMGGGDINGPL----FSKLLFKRGSLITSLLRSRDNKYKQ 281 Query: 296 -----FLEFVLPHIR-EG--KITYVEDVADGLEKAPEALVGLFHGKNVGKQVVVVAR 344 F E +LPH EG ++ V D + + EA + KN+GK V+ + + Sbjct: 282 MLVNAFTEQILPHFSTEGPQRLLPVLDRIYPVTEIQEAHKYMEANKNIGKIVLELPQ 338 >3UOG-A nrPDB Length = 363 Score = 186 bits (471), Expect = 2e-47, Method: Composition-based stats. Identities = 75/358 (20%), Positives = 128/358 (35%), Gaps = 41/358 (11%) Query: 7 QVILKDYVSGFPTESDFDFTTTTVELRVPE-GTNSVLVKNLYLSCDPYMRIRMGKPDPST 65 Q ++ ++ + TE+ E VPE G + ++V+ L +S + R ++ Sbjct: 21 QSMMSKWMQEWSTETVAPHDLKLAERPVPEAGEHDIIVRTLAVSLN--YRDKLVLETGMG 78 Query: 66 AALAQAYTPGQPIQGYGVSRIIESGHPDYKKGDLLWGI--VAW-----------EEYSVI 112 LA + P + G V + ++ GD + W Y + Sbjct: 79 LDLAFPFVPASDMSG--VVEAVGKSVTRFRPGDRVISTFAPGWLDGLRPGTGRTPAYETL 136 Query: 113 TPMTHAHFK----------IQHTDVPLSYYTGLLGMPGMTAYAGFYEVCSPKEGETVYVS 162 + + L G+TA+ E + G+ V V Sbjct: 137 GGAHPGVLSEYVVLPEGWFVAAPKSLDAAEASTLPCAGLTAWFALVEKGHLRAGDRVVVQ 196 Query: 163 AASGAVGQLVGQLAKMMGCYVVGSAGSKEKVDLLKTKFGFDDAFNYKEESDLTAALKRCF 222 +G V Q+AK G V+ ++ S+EK+D G D N EE + Sbjct: 197 G-TGGVALFGLQIAKATGAEVIVTSSSREKLDRA-FALGADHGINRLEEDWVERVYALTG 254 Query: 223 PNGIDIYFENVGGKMLDAVLVNMNMHGRIAVCGMISQYNLENQEGVHNLSNIIYKRIRIQ 282 G D E GG L L + GRI+V G++ + + G ++ K +Q Sbjct: 255 DRGADHILEIAGGAGLGQSLKAVAPDGRISVIGVLEGFEVSGPVG-----PLLLKSPVVQ 309 Query: 283 GFVVSDFYDKYSKFLEFVLPHIREGKITYVEDVADGLEKAPEALVGLFHGKNVGKQVV 340 G V + + LE ++ + + V D+ + PEAL L G GK V+ Sbjct: 310 GISVG-----HRRALEDLVGAVDRLGLKPVIDMRYKFTEVPEALAHLDRGP-FGKVVI 361 >2VCY-A nrPDB Length = 344 Score = 181 bits (460), Expect = 2e-46, Method: Composition-based stats. Identities = 63/285 (22%), Positives = 117/285 (41%), Gaps = 25/285 (8%) Query: 74 PGQPIQGY--GVSRII--ESGHPDYKKGDLLW----GIVAWEEYSVITPMTHAHFKIQHT 125 P P G GV++++ S K GD + G+ W +V + A ++ + Sbjct: 69 PELPAVGGNEGVAQVVAVGSNVTGLKPGDWVIPANAGLGTWRTEAVFS--EEALIQVP-S 125 Query: 126 DVPLSYYTGLLGMPGMTAYAGFYEVCSPKEGETVYVSAASGAVGQLVGQLAKMMGCYVVG 185 D+PL LG+ TAY + + G++V +A++ VGQ V Q+A +G + Sbjct: 126 DIPLQSAA-TLGVNPCTAYRMLMDFEQLQPGDSVIQNASNSGVGQAVIQIAAALGLRTIN 184 Query: 186 SAGSKEKVDLLKTKFGFDDAFNYKEESDLTAALKRCFPNGI---DIYFENVGGKMLDAVL 242 + + L + A + E +L + F + + VGGK +L Sbjct: 185 VVRDRPDIQKLSDRLKSLGAEHVITEEELRRPEMKNFFKDMPQPRLALNCVGGKSSTELL 244 Query: 243 VNMNMHGRIAVCGMISQYNLENQEGVHNLSNIIYKRIRIQGFVVSDFYDKYS--KFLEFV 300 + G + G + Q V ++S +I+K ++++GF +S + +S +F E + Sbjct: 245 RQLARGGTMVTYG-----GMAKQPVVASVSLLIFKDLKLRGFWLSQWKKDHSPDQFKELI 299 Query: 301 LPHI---REGKITYVEDVADGLEKAPEALVGLFHGKNVGKQVVVV 342 L R G++T L+ AL KQ++ + Sbjct: 300 LTLCDLIRRGQLTAPACSQVPLQDYQSALEASMKPFISSKQILTM 344 >3SLK-A nrPDB Length = 795 Score = 177 bits (448), Expect = 7e-45, Method: Composition-based stats. Identities = 61/314 (19%), Positives = 116/314 (36%), Gaps = 31/314 (9%) Query: 35 PEGTNSVLVKNLYLSCDPYMRIR-MGKPDPSTAALAQAYTPGQPIQGYGVSRIIESGHPD 93 P G V + MR + D A +G GV G Sbjct: 235 PLGDGEVRIA---------MRAAGVNFRDALIALGMYPGVASLGSEGAGVVVETGPGVTG 285 Query: 94 YKKGDLLWGIVA--WEEYSVITPMTHAHFKIQHTDVPLSYYTGLLGMPGMTAYAGFYEVC 151 GD + G++ + +V + + + +TAY ++ Sbjct: 286 LAPGDRVMGMIPKAFGPLAVADHRMVTRIPAGWSFA----RAASVPIVFLTAYYALVDLA 341 Query: 152 SPKEGETVYVSAASGAVGQLVGQLAKMMGCYVVGSAG--SKEKVDLLKTKFGFDDAFNYK 209 + GE++ V +A+G VG QLA+ +G V +A + V+L + +++ Sbjct: 342 GLRPGESLLVHSAAGGVGMAAIQLARHLGAEVYATASEDKWQAVELSREHLASSRTCDFE 401 Query: 210 EESDLTAALKRCFPNGIDIYFENVGGKMLDAVLVNMNMHGRIAVCGMISQYNLENQEGVH 269 ++ L G+D+ ++ G+ DA L + GR G + ++ + V Sbjct: 402 QQF-----LGATGGRGVDVVLNSLAGEFADASLRMLPRGGRFLELG---KTDVRDPVEVA 453 Query: 270 NLSNIIYKRIRIQGFVVSDFYDKYSKFLEFVLPHIREGKITYVEDV-ADGLEKAPEALVG 328 + + + Q F + + + L + EG++ V A + +APEAL Sbjct: 454 D----AHPGVSYQAFDTVEAGPQRIGEMLHELVELFEGRVLEPLPVTAWDVRQAPEALRH 509 Query: 329 LFHGKNVGKQVVVV 342 L ++VGK V+ + Sbjct: 510 LSQARHVGKLVLTM 523 >4A27-A nrPDB Length = 349 Score = 172 bits (435), Expect = 2e-43, Method: Composition-based stats. Identities = 75/297 (25%), Positives = 117/297 (39%), Gaps = 36/297 (12%) Query: 74 PGQP-IQGYGVSRIIE---SGHPDYKKGDLLWGIV---AWEEYSVITPMTHAHFKIQHTD 126 P P + G+ S I+E Y+ GD + V AW E V TP+ +KI D Sbjct: 58 PKTPLVPGFECSGIVEALGDSVKGYEIGDRVMAFVNYNAWAE-VVCTPVEFV-YKIPD-D 114 Query: 127 VPLSYYTGLLGMPGMTAYAGFYEVCSPKEGETVYVSAASGAVGQLVGQLAKMMGCYVVGS 186 + S M +TAY +EV + +EG +V V +A G VGQ V QL + V Sbjct: 115 MSFSEAAAF-PMNFVTAYVMLFEVANLREGMSVLVHSAGGGVGQAVAQLCSTVPNVTVFG 173 Query: 187 AGSKEKVDLLKTKFG--FDDAFNYKEESDLTAALKRCFPNGIDIYFENVGGKMLDAVLVN 244 S K + +K FD +Y +E +KR G+DI + + G L Sbjct: 174 TASTFKHEAIKDSVTHLFDRNADYVQE------VKRISAEGVDIVLDCLCGDNTGKGLSL 227 Query: 245 MNMHGRIAVCGMISQYNLEN-----------QEGVHNLSNIIYKRIRIQGFVVSDFYDKY 293 + G + G + E Q N + + I GF + + K Sbjct: 228 LKPLGTYILYGSSNMVTGETKSFFSFAKSWWQVEKVNPIKLYEENKVIAGFSLLNLLFKQ 287 Query: 294 SKF------LEFVLPHIREGKITYVEDVADGLEKAPEALVGLFHGKNVGKQVVVVAR 344 + +E ++ + KI V D LE+ EA+ + N+GK ++ V + Sbjct: 288 GRAGLIRGVVEKLIGLYNQKKIKPVVDSLWALEEVKEAMQRIHDRGNIGKLILDVEK 344 >1WLY-A nrPDB Length = 333 Score = 168 bits (426), Expect = 2e-42, Method: Composition-based stats. Identities = 60/343 (17%), Positives = 130/343 (37%), Gaps = 34/343 (9%) Query: 13 YVSGFPTESDFDFTTTTVELRVPEGTNSVLVKNLYLSC---DPYMRIRMGKPDPSTAALA 69 + G P +F + V P V ++N + D Y R A + Sbjct: 8 HKKGGP--DNFVWEEVKVGSPGP---GQVRLRNTAIGVNFLDTYHR----------AGIP 52 Query: 70 QAYTPGQP--IQGYGVSRIIES---GHPDYKKGDLLWG----IVAWEEYSVITPMTHAHF 120 G+P + G+ + ++E G D+ G+ + + A+ + + Sbjct: 53 HPLVVGEPPIVVGFEAAAVVEEVGPGVTDFTVGERVCTCLPPLGAYSQERLYPAEKLIKV 112 Query: 121 KIQHTDVPLSYYTGLLGMPGMTAYAGFYEVCSPKEGETVYVSAASGAVGQLVGQLAKMMG 180 + D+ + GL+ + GMTA ++ K G+ V + AA+G +G ++ A+ +G Sbjct: 113 -PKDLDLDDVHLAGLM-LKGMTAQYLLHQTHKVKPGDYVLIHAAAGGMGHIMVPWARHLG 170 Query: 181 CYVVGSAGSKEKVDLLKTKFGFDDAFNYKEESDLTAALKRCFPNGIDIYFENVGGKMLDA 240 V+G+ ++EK + + K G NY + + G+D+ ++++G L Sbjct: 171 ATVIGTVSTEEKAETAR-KLGCHHTINYSTQDFAEVVREITGGKGVDVVYDSIGKDTLQK 229 Query: 241 VLVNMNMHGRIAVCGMISQYN--LENQEGVHNLSNIIYKRIRIQGFVVSDFYDKYSKFLE 298 L + G A G S + E + ++ R + ++ + + + Sbjct: 230 SLDCLRPRGMCAAYGHASGVADPIRVVEDLGVRGSLFITRPALWHYMSNRSEID--EGSK 287 Query: 299 FVLPHIREGKITYVEDVADGLEKAPEALVGLFHGKNVGKQVVV 341 + ++ G + L +A A + + +G V++ Sbjct: 288 CLFDAVKAGVLHSSVAKTFPLREAAAAHKYMGGRQTIGSIVLL 330 >5A3V-A nrPDB Length = 329 Score = 162 bits (410), Expect = 2e-40, Method: Composition-based stats. Identities = 74/329 (22%), Positives = 127/329 (38%), Gaps = 35/329 (10%) Query: 25 FTTTTVELRVPEGTNSVLVKNLYLSCDPY-MRIRMGKPDPSTAALAQAYTPGQPIQGYGV 83 V + P +N V +K S +P +I+ G P P + G V Sbjct: 21 LEHVQVPVPTP-KSNEVCLKLEATSLNPVDWKIQKGMIRPFLPR-KFPCIPATDVAGEVV 78 Query: 84 SRIIESGHPDYKKGDLL------WGIVAWEEYSVITPMTHAHFKIQHTDVPLSYYTGLLG 137 + SG ++K GD + G E++V T ++ + L Sbjct: 79 E--VGSGVKNFKAGDKVVAVLSHLGGGGLAEFAVAT----EKLTVKRPQEVGAAEAAALP 132 Query: 138 MPGMTAYAGFYEVCSPKEGET-----VYVSAASGAVGQLVGQLAKMMGCYVVGSAGSKEK 192 + G+TA K T + V+AASG VG QLAK+ +V + G++ Sbjct: 133 VAGLTALQALTNPAGLKLDGTGKKANILVTAASGGVGHYAVQLAKLANAHVTATCGAR-N 191 Query: 193 VDLLKTKFGFDDAFNYKEESDLTAALKRCFPNGIDIYFENVGGKMLDAVLVNMNMHGRIA 252 ++ +K+ G D+ +YK AALK D G N++ +G++ Sbjct: 192 IEFVKS-LGADEVLDYKTPEG--AALKSPSGKKYDAVVHCANGIPFSVFEPNLSENGKV- 247 Query: 253 VCGMISQYNLENQEGVHNLSNIIYKRIRI-QGFVVSDFYDKYSKFLEFVLPHIREGKITY 311 ++ G + + K+I + + +V ++ LEF++ ++EGK+ Sbjct: 248 ---------IDITPGPNAMWTYAVKKITMSKKQLVPLLLIPKAENLEFMVNLVKEGKVKT 298 Query: 312 VEDVADGLEKAPEALVGLFHGKNVGKQVV 340 V D L KA +A G GK +V Sbjct: 299 VIDSKHPLSKAEDAWAKSIDGHATGKIIV 327 >1QOR-A nrPDB Length = 327 Score = 161 bits (408), Expect = 3e-40, Method: Composition-based stats. Identities = 62/310 (20%), Positives = 109/310 (35%), Gaps = 15/310 (4%) Query: 37 GTNSVLVKNLYLSC---DPYMRIRMGKPDPSTAALAQAYTPGQPIQGYGVSRIIESGHPD 93 N + V+N + D Y+R + P + G G + + SG Sbjct: 27 AENEIQVENKAIGINFIDTYIRSGLYPPP------SLPSGLGTEAAG--IVSKVGSGVKH 78 Query: 94 YKKGDLL-WGIVAWEEYSVITPMTHAHFKIQHTDVPLSYYTGLLGMPGMTAYAGFYEVCS 152 K GD + + A YS + + I + + G+T Y + Sbjct: 79 IKAGDRVVYAQSALGAYSSVHNIIADKAAILPAAISFEQAAASF-LKGLTVYYLLRKTYE 137 Query: 153 PKEGETVYVSAASGAVGQLVGQLAKMMGCYVVGSAGSKEKVDLLKTKFGFDDAFNYKEES 212 K E AA+G VG + Q AK +G ++G+ G+ +K K G NY+EE Sbjct: 138 IKPDEQFLFHAAAGGVGLIACQWAKALGAKLIGTVGTAQKAQ-SALKAGAWQVINYREED 196 Query: 213 DLTAALKRCFPNGIDIYFENVGGKMLDAVLVNMNMHGRIAVCGMISQYNLENQEGVHNLS 272 + + + + +++VG + L + G + G S G+ N Sbjct: 197 LVERLKEITGGKKVRVVYDSVGRDTWERSLDCLQRRGLMVSFGNSSGAVTGVNLGILNQK 256 Query: 273 NIIY-KRIRIQGFVVSDFYDKYSKFLEFVLPHIREGKITYVEDVADGLEKAPEALVGLFH 331 +Y R +QG++ + + F L K+ E L+ A A L Sbjct: 257 GSLYVTRPSLQGYITTREELTEASNELFSLIASGVIKVDVAEQQKYPLKDAQRAHEILES 316 Query: 332 GKNVGKQVVV 341 G +++ Sbjct: 317 RATQGSSLLI 326 >5ENV-A nrPDB Length = 347 Score = 160 bits (404), Expect = 8e-40, Method: Composition-based stats. Identities = 58/242 (23%), Positives = 106/242 (43%), Gaps = 18/242 (7%) Query: 104 VAWEEYSVITPMTHAHFKIQHTDVPLSYYTGLLGMPGMTAYAGFYEVCSPKEGETVYVSA 163 ++++Y+ + AH Q TD L+ +L G+T Y + + G V +S Sbjct: 123 GSFQQYATADAVQAAHI-PQGTD--LAQVAPIL-CAGITVYKAL-KSANLMAGHWVAISG 177 Query: 164 ASGAVGQLVGQLAKMMGCYVVGSAGSKEKVDLLKTKFGFDDAFNYKEESDLTAALKRCFP 223 A+G +G L Q AK MG V+G G + K +L ++ G + ++ +E D+ A+ + Sbjct: 178 AAGGLGSLAVQYAKAMGYRVLGIDGGEGKEELFRS-IGGEVFIDFTKEKDIVGAVLKATD 236 Query: 224 NGID-IYFENVGGKMLDAVLVNMNMHGRIAVCGMISQYNLENQEGVHNLSNIIYKRIRIQ 282 G + +V ++A + +G + GM + + ++ N + K I I Sbjct: 237 GGAHGVINVSVSEAAIEASTRYVRANGTTVLVGMPAG-----AKCCSDVFNQVVKSISIV 291 Query: 283 GFVVSDFYDKYSKFLEFVLPHIREGKITYVEDVADGLEKAPEALVGLFHGKNVGKQVVVV 342 G V + D + L+F + + I V GL PE + G+ VG+ VV Sbjct: 292 GSYVGNRADTR-EALDFFARGLVKSPIKVV-----GLSTLPEIYEKMEKGQIVGRYVVDT 345 Query: 343 AR 344 ++ Sbjct: 346 SK 347 >3QWB-A nrPDB Length = 334 Score = 158 bits (400), Expect = 3e-39, Method: Composition-based stats. Identities = 79/347 (22%), Positives = 135/347 (38%), Gaps = 29/347 (8%) Query: 6 KQVILKDYVSGFPTESDFDFTTTTVELRVP-EGTNSVLVKNLYLSC---DPYMRIRMGKP 61 ++VIL D + G+ + VP +L+KN Y + Y R Sbjct: 9 QKVILIDEIGGYDV-------IKYEDYPVPSISEEELLIKNKYTGVNYIESYFR------ 55 Query: 62 DPSTAALAQAYTPGQPIQGYGVSRIIESGHPDYKKGDLL--WGIVAWEEYSVITPMTHAH 119 + Y G+ G V++ G +++ GD + + +YS I+ Sbjct: 56 -KGIYPCEKPYVLGREASGTVVAK--GKGVTNFEVGDQVAYISNSTFAQYSKISSQGPVM 112 Query: 120 FKIQHT-DVPLS-YYTGLLGMPGMTAYAGFYEVCSPKEGETVYVSAASGAVGQLVGQLAK 177 + T D L Y GLL + +TA + E K+G+ V + AA+G VG ++ QL K Sbjct: 113 KLPKGTSDEELKLYAAGLLQV--LTALSFTNEAYHVKKGDYVLLFAAAGGVGLILNQLLK 170 Query: 178 MMGCYVVGSAGSKEKVDLLKTKFGFDDAFNYKEESDLTAALKRCFPNGIDIYFENVGGKM 237 M G + + A + EK+ + K ++G + N +E L LK G+D F++VG Sbjct: 171 MKGAHTIAVASTDEKLKIAK-EYGAEYLINASKEDILRQVLKFTNGKGVDASFDSVGKDT 229 Query: 238 LDAVLVNMNMHGRIAVCGMISQYNLENQEGVHNLSNIIYKRIRIQGFVVSDFYDKYSKFL 297 + L + G G S + NI R ++ G++ KY + Sbjct: 230 FEISLAALKRKGVFVSFGNASGLIPPFSITRLSPKNITLVRPQLYGYIADPEEWKY--YS 287 Query: 298 EFVLPHIREGKITYVEDVADGLEKAPEALVGLFHGKNVGKQVVVVAR 344 + + K+ L A + K VGK V+ + + Sbjct: 288 DEFFGLVNSKKLNIKIYKTYPLRDYRTAAADIESRKTVGKLVLEIPQ 334 >3TQH-A nrPDB Length = 321 Score = 151 bits (381), Expect = 4e-37, Method: Composition-based stats. Identities = 70/322 (21%), Positives = 112/322 (34%), Gaps = 40/322 (12%) Query: 30 VELRVPE-GTNSVLVKNLYLSCDPYMRIRMGKPDPSTAALAQAYTPGQPI-QGYGVSRII 87 V+ PE N +L+K S +P K + +A+ P GY S + Sbjct: 24 VDTPTPEYRKNQMLIKVHAASLNPI----DYKTRNGSGFVAKKLKNNLPSGLGYDFSGEV 79 Query: 88 ---ESGHPDYKKGDLLWGIVAWEEYSVITPMTHAHFKIQHTDVPLSYY-------TGLLG 137 S + GD + GI + ++ P +A + D + L Sbjct: 80 IELGSDVNNVNIGDKVMGIAGFPDH----PCCYAEYVCASPDTIIQKLEKLSFLQAASLP 135 Query: 138 MPGMTAYAGFYEVCSPKEGETVYVSAASGAVGQLVGQLAKMMGCYVVGSAGSKEKVDLLK 197 G+TA + K+G+ V + A +G VG L QLAK G V+ +A + LK Sbjct: 136 TAGLTALQALNQ-AEVKQGDVVLIHAGAGGVGHLAIQLAKQKGTTVITTASKR-NHAFLK 193 Query: 198 TKFGFDDAFNYKEESDLTAALKRCFPNGIDIYFENVGGKMLDAVLVNMNMHGRIAVCGMI 257 G + NY EE L A +D + VGG + + + G I I Sbjct: 194 -ALGAEQCINYHEEDFLLAI-----STPVDAVIDLVGGDVGIQSIDCLKETGCIVSVPTI 247 Query: 258 SQYNLENQEGVHNLSNIIYKRIRIQGFVVSDFYDKYSKFLEFVLPHIREGKITYVEDVAD 317 + + + K+ + F + L ++ + E K+ Sbjct: 248 TAGRVIE----------VAKQKHRRAF--GLLKQFNIEELHYLGKLVSEDKLRIEISRIF 295 Query: 318 GLEKAPEALVGLFHGKNVGKQV 339 L +A A L G GK V Sbjct: 296 QLSEAVTAHELLETGHVRGKLV 317 >4RVS-A nrPDB Length = 329 Score = 145 bits (366), Expect = 2e-35, Method: Composition-based stats. Identities = 65/327 (19%), Positives = 104/327 (31%), Gaps = 24/327 (7%) Query: 25 FTTTTVELRVPEGTNSVLVKNLYLSC---DPYMRIRMGKPDPSTAALAQAYTPGQPIQG- 80 P G +L+K + D Y R + G + G Sbjct: 16 LRHVDQPQPQP-GHGELLIKAEAIGVNFIDTYFR-------SGQYPRELPFVIGSEVCGT 67 Query: 81 -YGVSRIIESGHPDYKKGDLLWGIVAWEEYSVITPMTHAHFKIQHTDVPLSYYTGLLGMP 139 V + + GD + A Y+ A + D S + Sbjct: 68 VEAVGPGVTAADTAISVGDRVVSASANGAYAEFC-TAPASLTAKVPDDVTSEVAASALLK 126 Query: 140 GMTAYAGFYEVCSPKEGETVYVSAASGAVGQLVGQLAKMMGCYVVGSAGSKEKVDLLKTK 199 G+TA+ V K G+TV V A +G VG ++ Q A +G V+ + + EK L K Sbjct: 127 GLTAHYLLKSVYPVKRGDTVLVHAGAGGVGLILTQWATHLGVRVITTVSTAEKAKLSKDA 186 Query: 200 FGFDDAFNYKEESD--LTAALKRCFPNGIDIYFENVGGKMLDAVLVNMNMHGRIAVCGMI 257 G D +Y E++ + G+ ++ VG DA L ++ + G +A+ G Sbjct: 187 -GADVVLDYPEDAWQFAGRVRELTGGTGVQAVYDGVGATTFDASLASLAVRGTLALFGAA 245 Query: 258 SQYNLENQEGVHNLSNIIYKRIRIQGFVVSDFYDKYSKFLEFVLPHIREGK---ITYVED 314 S V + + + F +F IT Sbjct: 246 SG----PVPPVDPQRLNAAGSVYLTRPSLFHFTRTGEEFSWRAAELFDAIGNEAITVAVG 301 Query: 315 VADGLEKAPEALVGLFHGKNVGKQVVV 341 L A A L K VG V++ Sbjct: 302 GRYPLADALRAHQDLEARKTVGSVVLL 328 >3JYN-A nrPDB Length = 325 Score = 144 bits (364), Expect = 3e-35, Method: Composition-based stats. Identities = 54/276 (19%), Positives = 99/276 (35%), Gaps = 4/276 (1%) Query: 67 ALAQAYTPGQPIQGYGVSRIIESGHPDYKKGDLL-WGIVAWEEYSVITPMTHAHFKIQHT 125 A G +G GV + +K GD + +G YS + + A+ Sbjct: 52 YPAPFLPSGLGAEGAGVVEAVGDEVTRFKVGDRVAYGTGPLGAYSEVHVLPEANLVKLAD 111 Query: 126 DVPLSYYTGLLGMPGMTAYAGFYEVCSPKEGETVYVSAASGAVGQLVGQLAKMMGCYVVG 185 V L+ + G+T + K GE + AA+G VG L Q AK +G ++G Sbjct: 112 SVSFEQAAALM-LKGLTVQYLLRQTYQVKPGEIILFHAAAGGVGSLACQWAKALGAKLIG 170 Query: 186 SAGSKEKVDLLKTKFGFDDAFNYKEESDLTAALKRCFPNGIDIYFENVGGKMLDAVLVNM 245 + S EK K G + +Y E L+ + ++ VG L ++ Sbjct: 171 TVSSPEKAAHAK-ALGAWETIDYSHEDVAKRVLELTDGKKCPVVYDGVGQDTWLTSLDSV 229 Query: 246 NMHGRIAVCGMISQYNLENQEGVHNLSNIIYKRIRIQGFVVSDFYDKYSKFLEFVLPHIR 305 G + G S G+ + +Y G ++ + + + + + Sbjct: 230 APRGLVVSFGNASGPVSGVNLGILAQKDSVYVTRPTLGSYANNAQNLQTMA-DELFDMLA 288 Query: 306 EGKITYVEDVADGLEKAPEALVGLFHGKNVGKQVVV 341 GK+ L+ A +A + L + G +++ Sbjct: 289 SGKLKVDGIEQYALKDAAKAQIELSARRTTGSTILI 324 >5K1S-A nrPDB Length = 362 Score = 136 bits (341), Expect = 2e-32, Method: Composition-based stats. Identities = 64/284 (22%), Positives = 102/284 (35%), Gaps = 18/284 (6%) Query: 61 PDPSTAALAQAYTPGQPIQGYGVSRIIESGHPDYKKGDLLWGI---VAWEEYSVITPMTH 117 PD Q + + + K + +G + ++ V Sbjct: 90 PDTPGWKTGDRAATLQRMSCGDCALCRSGRNSLCKTDNRFFGEELPGGYAQFMVAPVGGL 149 Query: 118 AHFKIQHTDVPLSYYTGLLGMPGMTAYAGFYEVCSPKEGETVYVSAASGAVGQLVGQLAK 177 +P + + G TA + GETV ++ ASG VG QLA+ Sbjct: 150 GRV---PASLPWNEAATVCCTTG-TAVHTVRTRGKVRAGETVLITGASGGVGLSSVQLAR 205 Query: 178 MMGCYVVGSAGSKEKVDLLKTKFGFDDAFNYKEESDLTAALKRCFPNGIDIYFENVGGKM 237 + G V+ S+ KV LK + G D+ + + KR G+D+ E VG Sbjct: 206 LDGARVIAVTSSEAKVQALK-EAGADEVIVSRGLDFASDVRKRTQGAGVDVAVEIVGSAT 264 Query: 238 LDAVLVNMNMHGRIAVCGMISQYNLENQEGVHNLSNIIYKRIRIQGFVVSDFYDKYSKFL 297 D L +M GR+ V G NLE+ N +I K + I G + L Sbjct: 265 FDQTLKSMAPGGRVVVVG-----NLESGMVQLNPGLVIVKELEILGAYATT-----QAEL 314 Query: 298 EFVLPHIREGKITYVEDVADGLEKAPEALVGLFHGKNVGKQVVV 341 + L G + A L +A +A L + + G+ V+V Sbjct: 315 DEALRLTATGGVRQFVTDAVPLAEAAKAHFRLENREVAGRLVLV 358 >4J6F-A nrPDB Length = 382 Score = 127 bits (318), Expect = 9e-30, Method: Composition-based stats. Identities = 52/238 (21%), Positives = 81/238 (34%), Gaps = 17/238 (7%) Query: 104 VAWEEYSVITPMTHAHFKIQHTDVPLSYYTGLLGMPGMTAYAGFYEVCSPKEGETVYVSA 163 + EY + TD+ L +T E GETV V+ Sbjct: 160 GGYAEYMALPAENAHVVATDLTDIEL----ATFCCAYLTGERML-ERARLAAGETVLVTG 214 Query: 164 ASGAVGQLVGQLAKMMGCYVVGSAGSKEKVDLLKTKFGFDDAFNYKEESDLTAALKRCFP 223 ASG VG + QLA+ G + AG ++ +L G + A Sbjct: 215 ASGGVGSAIIQLARARGAVPIAVAGPGKEAAMLD--IGAQAVVTRGQGDLAEAVEAASGG 272 Query: 224 NGIDIYFENVGGKMLDAVLVNMNMHGRIAVCGMISQYNLENQEGVHNLSNIIYKRIRIQG 283 ID+ + VGG + + +L + GR G I+ +L + K++ + G Sbjct: 273 RPIDVVADLVGGPLFNDLLKILRPEGRYTTAGAIAG-----PVVQLDLRTMYLKQLELHG 327 Query: 284 FVVSDFYDKYSKFLEFVLPHIREGKITYVEDVADGLEKAPEALVGLFHGKNVGKQVVV 341 D ++ +I E KI + L + A VGK VVV Sbjct: 328 SSQGSRADFRR-----LVRYIEEKKIRPLVGGVYPLSEFHRAQTDFMAKNFVGKLVVV 380 >3FBG-A nrPDB Length = 346 Score = 116 bits (291), Expect = 1e-26, Method: Composition-based stats. Identities = 62/334 (18%), Positives = 120/334 (35%), Gaps = 28/334 (8%) Query: 25 FTTTTVELRVPEGTNSVLVKNLYLSCDPYMRIRMGKPDPSTAALAQAYTPGQPIQGYGVS 84 F T +++ P + +LVK +S +P + G GV Sbjct: 20 FKTFNLDIPEP-KVHEILVKIQSISVNP-----VDTKQRLMDVSKAPRVLG--FDAIGVV 71 Query: 85 RIIESGHPDYKKGDLLWGIVAWEEYSVITPMTH--AHFKIQHTDVPLSYYTGLLGMPGMT 142 + + + +GD+++ + ++ + + L + G+T Sbjct: 72 ESVGNEVTMFNQGDIVYYSGSPDQNGSNAEYQLINERLVAKAPKNISAEQAVSLPLTGIT 131 Query: 143 AYAGFYEVCSP------KEGETVYVSAASGAVGQLVGQLAKMMGCYVVGSAGSKEKVDLL 196 AY ++V EG+T+ + +G VG + Q+AK G V+ +A E ++ Sbjct: 132 AYETLFDVFGISRNRNENEGKTLLIINGAGGVGSIATQIAKAYGLRVITTASRNETIEWT 191 Query: 197 KTKFGFDDAFNYKEESDLTAALKRCFPNGIDIYFENVGGKM-LDAVLVNMNMHGRIAVCG 255 K K G D N+KE L K +D F M D ++ + G IA Sbjct: 192 K-KMGADIVLNHKE--SLLNQFKTQGIELVDYVFCTFNTDMYYDDMIQLVKPRGHIAT-- 246 Query: 256 MISQYNLENQEGVHNLSNIIYKRIRIQGFVVSDFYD--KYSKFLEFVLPHIREGKITYVE 313 I + + ++ + + ++ D K+ ++LE + + + Sbjct: 247 -IVAFENDQDLNALKPKSLSFSHEFMFARPLNQTDDMIKHHEYLEDITNKVEQNIYQPTT 305 Query: 314 D-VADGL--EKAPEALVGLFHGKNVGKQVVVVAR 344 V +GL E +A L +GK V+ + Sbjct: 306 TKVIEGLTTENIYQAHQILESNTMIGKLVINLNE 339 >2VN8-A nrPDB Length = 375 Score = 116 bits (291), Expect = 1e-26, Method: Composition-based stats. Identities = 70/343 (20%), Positives = 125/343 (36%), Gaps = 34/343 (9%) Query: 27 TTTVELRVPEGTNSVLVKNLYLSCDPY---MRIRMG------KPDPSTAALAQ---AYTP 74 T + + + N V+VK S +P MR G K DP + T Sbjct: 39 TQNMMMPIIHYPNEVIVKVHAASVNPIDVNMRSGYGATALNMKRDPLHVKIKGEEFPLTL 98 Query: 75 GQPIQGYGVSRIIESGHPDYKKGDLLWG-IVAWEEYSVITPMTHAHFKIQHTDVPLSYY- 132 G+ + G V +K GD +W + W++ ++ + + ++ H L++ Sbjct: 99 GRDVSG--VVMECGLDVKYFKPGDEVWAAVPPWKQGTLSEFVVVSGNEVSHKPKSLTHTQ 156 Query: 133 TGLLGMPGMTAYAGFYEVCSPKE----GETVYVSAASGAVGQLVGQLAKMMGCYVVGSAG 188 L +TA++ +V + G+ V + ASG VG Q+ K +V Sbjct: 157 AASLPYVALTAWSAINKVGGLNDKNCTGKRVLILGASGGVGTFAIQVMKAWDAHVTAVCS 216 Query: 189 SKEKVDLLKTKFGFDDAFNYKEESDLTAALKRCFPNGIDIYFENVGGKMLDAVLVNMNMH 248 + L K G DD +YK + LK D +NVGG + Sbjct: 217 --QDASELVRKLGADDVIDYKS-GSVEEQLKSL--KPFDFILDNVGGSTETWAPDFLKKW 271 Query: 249 GRIAVCGMISQYNLE-NQEGVHN---LSNIIYKRIRIQGFVVS-----DFYDKYSKFLEF 299 +++ + L ++ G+ + + + ++ F F+ L+ Sbjct: 272 SGATYVTLVTPFLLNMDRLGIADGMLQTGVTVGSKALKHFWKGVHYRWAFFMASGPCLDD 331 Query: 300 VLPHIREGKITYVEDVADGLEKAPEALVGLFHGKNVGKQVVVV 342 + + GKI V + K PEA + + G GK V+ V Sbjct: 332 IAELVDAGKIRPVIEQTFPFSKVPEAFLKVERGHARGKTVINV 374 >4EYE-A nrPDB Length = 342 Score = 114 bits (286), Expect = 5e-26, Method: Composition-based stats. Identities = 52/270 (19%), Positives = 98/270 (36%), Gaps = 15/270 (5%) Query: 78 IQGYGVSRIIESG--HPDYKKGDLLWGIVAWEEYSVITPMTHAHFKIQHTDVPLSYYTGL 135 + G + ++ S K GD + Y+ + ++ + + L Sbjct: 81 VPGIETAGVVRSAPEGSGIKPGDRVMAFNFIGGYAERVAVAPSNILPTPPQLDDAEAVAL 140 Query: 136 LGMPGMTAYAGFYEVCSPKEGETVYVSAASGAVGQLVGQLAKMMGCYVVGSAGSKEKVDL 195 + T Y + + GETV V A+G +G Q+AK MG V+ + Sbjct: 141 IA-NYHTMYFAYARRGQLRAGETVLVLGAAGGIGTAAIQIAKGMGAKVIAVVNRTAATEF 199 Query: 196 LKTKFGFDDAFNYKEESDLTAALKRCFPNGIDIYFENVGGKMLDAVLVNMNMHGRIAVCG 255 +K+ G D EE A + G+D+ + +GG D + + GR+ V G Sbjct: 200 VKS-VGADIVLP-LEEGWAKAVREATGGAGVDMVVDPIGGPAFDDAVRTLASEGRLLVVG 257 Query: 256 MISQYNLENQEGVHNLSNIIYKRIRIQGFVVSDFYDKYSKFLEF----VLPHIREGKITY 311 + ++ ++ + + G +F ++ +L + + EG + Sbjct: 258 FAAGG-----IPTIKVNRLLLRNASLIGVAWGEFLRTHADYLYETQAGLEKLVAEG-MRP 311 Query: 312 VEDVADGLEKAPEALVGLFHGKNVGKQVVV 341 L + +AL GK GK V+V Sbjct: 312 PVSARIPLSEGRQALQDFADGKVYGKMVLV 341 >3PII-A nrPDB Length = 339 Score = 108 bits (270), Expect = 3e-24, Method: Composition-based stats. Identities = 62/321 (19%), Positives = 102/321 (31%), Gaps = 47/321 (14%) Query: 56 IRMGKPDPSTAALAQAYTPGQPI----QGYGVSRIIESGHPDYKKGDLLWGIVAWEEYSV 111 + D A P P+ +G G+ + G K GD + + Sbjct: 35 CGVCHTDLHAAHGDWPVKPKLPLIPGHEGVGIVEEVGPGVTHLKVGDRVGIPWLYSACGH 94 Query: 112 ITPM---------------------------THAHFKIQHTDVPLSYYTGLLGMPGMTAY 144 A + ++ D + G+T Y Sbjct: 95 CDYCLSGQETLCEHQKNAGYSVDGGYAEYCRAAADYVVKIPDNLSFEEAAPIFCAGVTTY 154 Query: 145 AGFYEVCSPKEGETVYVSAASGAVGQLVGQLAKMMGCYVVGSAGSKEKVDLLKTKFGFDD 204 +V K GE V + G G + Q AK MG VV EK++L K + G D Sbjct: 155 KAL-KVTGAKPGEWVAIYG-IGGFGHVAVQYAKAMGLNVVAVDIGDEKLELAK-ELGADL 211 Query: 205 AFNYKEESDLTAALKRCFPNGIDIYFENVGGKMLDAVLVNMNMHGRIAVCGMISQYNLEN 264 N +E D +K V + ++ G + G L Sbjct: 212 VVNPLKE-DAAKFMKEKVGGVHAAVVTAVSKPAFQSAYNSIRRGGACVLVG------LPP 264 Query: 265 QEGVHNLSNIIYKRIRIQGFVVSDFYDKYSKFLEFVLPHIREGKITYVEDVADGLEKAPE 324 +E + + + I+I G +V D L+ L EGK+ + +V LEK E Sbjct: 265 EEMPIPIFDTVLNGIKIIGSIVGTRKD-----LQEALQFAAEGKVKTIIEV-QPLEKINE 318 Query: 325 ALVGLFHGKNVGKQVVVVARE 345 + G+ G+ V+ + + Sbjct: 319 VFDRMLKGQINGRVVLTLEDK 339 >5YAT-A nrPDB Length = 350 Score = 107 bits (266), Expect = 8e-24, Method: Composition-based stats. Identities = 43/242 (17%), Positives = 98/242 (40%), Gaps = 18/242 (7%) Query: 104 VAWEEYSVITPMTHAHFKIQHTDVPLSYYTGLLGMPGMTAYAGFYEVCSPKEGETVYVSA 163 ++++Y+ A + L+ +L G+T Y + + G+ V +S Sbjct: 126 GSFQQYATADATQAARI---PKEADLAEVAPIL-CAGITVYKAL-KTADLRIGQWVAISG 180 Query: 164 ASGAVGQLVGQLAKMMGCYVVGSAGSKEKVDLLKTKFGFDDAFNY-KEESDLTAALKRCF 222 A G +G L Q AK +G V+G G +K + +K+ G + ++ K + + K Sbjct: 181 AGGGLGSLAVQYAKALGLRVLGIDGGADKGEFVKS-LGAEVFVDFTKTKDVVAEVQKLTN 239 Query: 223 PNGIDIYFENVGGKMLDAVLVNMNMHGRIAVCGMISQYNLENQEGVHNLSNIIYKRIRIQ 282 + +V ++ + + G++ + G+ S + ++ + K I I+ Sbjct: 240 GGPHGVINVSVSPHAINQSVQYVRTLGKVVLVGLPSGAVVN-----SDVFWHVLKSIEIK 294 Query: 283 GFVVSDFYDKYSKFLEFVLPHIREGKITYVEDVADGLEKAPEALVGLFHGKNVGKQVVVV 342 G V + D ++ ++ + + I + GL + + + G +G+ VV Sbjct: 295 GSYVGNREDS-AEAIDLFTRGLVKAPIKII-----GLSELAKVYEQMEAGAIIGRYVVDT 348 Query: 343 AR 344 ++ Sbjct: 349 SK 350 >1O89-A nrPDB Length = 345 Score = 106 bits (263), Expect = 2e-23, Method: Composition-based stats. Identities = 49/217 (22%), Positives = 87/217 (40%), Gaps = 15/217 (6%) Query: 130 SYYTGLLGMPGMTAY--AGFYEVCSPKEGE-TVYVSAASGAVGQLVGQLAKMMGCYVVGS 186 + ++G G TA E + + + V+ ASG VG L +G VV Sbjct: 139 ARKAMIIGTAGFTAMLCVMALEDAGVRPQDGEIVVTGASGGVGSTAVALLHKLGYQVVAV 198 Query: 187 AGSKEKVDLLKTKFGFDDAFNYKEESDLTAALKRCFPNGIDIYFENVGGKMLDAVLVNMN 246 +G + + LK+ G E ++ K+ + ID VG K+L VL MN Sbjct: 199 SGRESTHEYLKS-LGASRVLPRDEFAESRPLEKQVWAGAID----TVGDKVLAKVLAQMN 253 Query: 247 MHGRIAVCGMISQYNLENQEGVHNLSNIIYKRIRIQGFV-VSDFYDKYSKFLEFVLPHIR 305 G +A CG+ + L + I + +R+QG V ++ ++ + ++ + Sbjct: 254 YGGCVAACGLAGGFTL-----PTTVMPFILRNVRLQGVDSVMTPPERRAQAWQRLVADLP 308 Query: 306 EGKITYVEDVADGLEKAPEALVGLFHGKNVGKQVVVV 342 E T L +AP + + + G+ +V V Sbjct: 309 ESFYTQAAKEI-SLSEAPNFAEAIINNQIQGRTLVKV 344 >5LB9-A nrPDB Length = 385 Score = 105 bits (262), Expect = 2e-23, Method: Composition-based stats. Identities = 58/358 (16%), Positives = 107/358 (29%), Gaps = 39/358 (10%) Query: 16 GFPTESDFDFTTTTVELRVPEGTNSVLVKNLYLSCDPYMRIRMGKPDPSTAALAQAY--- 72 G P D FT + N V+VK L +P ++ PS A + Sbjct: 34 GEP--KDVLFTQSFEIDDDNLAPNEVIVKTLGSPVNPSDINQIQGVYPSKPAKTTGFGTT 91 Query: 73 TPGQPIQGYGVSRI--IESGHPDYKKGDLLW----GIVAWEEYSVITPMTHAHFKIQH-- 124 P P G+ + + S + GD + W +++ Sbjct: 92 EPAAPCGNEGLFEVIKVGSNVSSLEAGDWVIPSHVNFGTWRTHALGNDDDFIKLPNPAQS 151 Query: 125 -----TDVPLSYYTGLLGMPGMTAYAGFYEVCSPKEG-ETVYVSAASGAVGQLVGQLAKM 178 + + + + AY G + + + AVG+ Q+ K+ Sbjct: 152 KANGKPNGLTINQGATISVNPLVAYLMLTHYVKLTPGKDWFIQNGGTSAVGKYASQIGKL 211 Query: 179 MGCYVVGSAGSKEKVD---LLKTKFGFDDAF-----NYKEESDLTAALKRCFPNGIDIYF 230 + + + +D + G N +E + + Sbjct: 212 LNFNSISVIRDRPNLDEVVASLKELGATQVITEDQNNSREFGPTIKEWIKQSGGEAKLAL 271 Query: 231 ENVGGKMLDAVLVNMNMHGRIAVCGMISQYNLENQEGVHNLSNIIYKRIRIQGFVVSDFY 290 VGGK + +N +G + G + Q S I+K GF V++ Sbjct: 272 NCVGGKSSTGIARKLNNNGLMLTYG-----GMSFQPVTIPTSLYIFKNFTSAGFWVTELL 326 Query: 291 DKYSK----FLEFVLPHIREGKI---TYVEDVADGLEKAPEALVGLFHGKNVGKQVVV 341 + L ++ EGK+ +E + DG + E GKQ++ Sbjct: 327 KNNKELKTSTLNQIIAWYEEGKLTDAKSIETLYDGTKPLHELYQDGVANSKDGKQLIT 384 >1LLU-A nrPDB Length = 342 Score = 104 bits (258), Expect = 7e-23, Method: Composition-based stats. Identities = 65/362 (17%), Positives = 116/362 (32%), Gaps = 64/362 (17%) Query: 13 YVSGFPTESDFDFTTTTVELRVPEGTNSVLVKNLYLSCDPYMRIRMGKPDPSTAALAQAY 72 + G P V L P VLVK + + Sbjct: 13 HAYGAP----LRIEEVKVPLPGP---GQVLVK-----IEASGVCHTDLHAAEGDWPVKPP 60 Query: 73 TPGQPI-QGYGVSRIIESGHPDYKKGDLL------------------WGI---------- 103 P P +G G + SG K+GD + W Sbjct: 61 LPFIPGHEGVGYVAAVGSGVTRVKEGDRVGIPWLYTACGCCEHCLTGWETLCESQQNTGY 120 Query: 104 ---VAWEEYSVITPMTHAHFKIQHTDVPLSYYTGLLGMPGMTAYAGFYEVCSPKEGETVY 160 + EY + P + I +V + +L G+T Y G + + + G+ V Sbjct: 121 SVNGGYAEYVLADPN---YVGILPKNVEFAEIAPIL-CAGVTVYKGLKQT-NARPGQWVA 175 Query: 161 VSAASGAVGQLVGQLAKMMGCYVVGSAGSKEKVDLLKTKFGFDDAFNYKEESDLTAALKR 220 +S G +G + Q A+ MG +V K++L + K G N ++E + A + Sbjct: 176 ISG-IGGLGHVAVQYARAMGLHVAAIDIDDAKLELAR-KLGASLTVNARQEDPVEAIQRD 233 Query: 221 CFPNGIDIYFENVGGKMLDAVLVNMNMHGRIAVCGMISQYNLENQEGVHNLSNIIYKRIR 280 + V + G IA+ G L + + +++ K + Sbjct: 234 IGGA-HGVLVTAVSNSAFGQAIGMARRGGTIALVG------LPPGDFPTPIFDVVLKGLH 286 Query: 281 IQGFVVSDFYDKYSKFLEFVLPHIREGKITYVEDVADGLEKAPEALVGLFHGKNVGKQVV 340 I G +V D + L+F + + I L+ + L + G+ G+ V+ Sbjct: 287 IAGSIVGTRAD-LQEALDFAGEGLVKATIHP-----GKLDDINQILDQMRAGQIEGRIVL 340 Query: 341 VV 342 + Sbjct: 341 EM 342 >3MEQ-A nrPDB Length = 365 Score = 104 bits (258), Expect = 8e-23, Method: Composition-based stats. Identities = 50/242 (20%), Positives = 91/242 (37%), Gaps = 20/242 (8%) Query: 104 VAWEEYSVITPMTHAHFKIQHTDVPLSYYTGLLGMPGMTAYAGFYEVCSPKEGETVYVSA 163 + EY V P H ++ + +L G+T Y G +V K G+ V +S Sbjct: 143 GGFAEYVVADPNFVGHL---PKNIDFNEIAPVL-CAGVTVYKGL-KVTDTKPGDWVVISG 197 Query: 164 ASGAVGQLVGQLAKMMGCYVVGSAGSKEKVDLLKTKFGFDDAFNYKEESDLTAALKRCFP 223 G +G + Q A+ MG V K+DL + + G N K +D A +++ Sbjct: 198 -IGGLGHMAVQYARAMGLNVAAVDIDDRKLDLAR-RLGATVTVNAKTVADPAAYIRKETD 255 Query: 224 NGIDIYFEN-VGGKMLDAVLVNMNMHGRIAVCGMISQYNLENQEGVHNLSNIIYKRIRIQ 282 G V K + L + G +++ G L + ++ N++ + ++ Sbjct: 256 GGAQGVLVTAVSPKAFEQALGMVARGGTVSLNG------LPPGDFPLSIFNMVLNGVTVR 309 Query: 283 GFVVSDFYDKYSKFLEFVLPHIREGKITYVEDVADGLEKAPEALVGLFHGKNVGKQVVVV 342 G +V D L+ L +GK+ LE + G G+ V+ + Sbjct: 310 GSIVGTRLD-----LQESLDFAADGKVKATIQ-TGKLEDINAIFDDMRQGNIEGRIVMDL 363 Query: 343 AR 344 + Sbjct: 364 TQ 365 >2EER-A nrPDB Length = 347 Score = 103 bits (257), Expect = 1e-22, Method: Composition-based stats. Identities = 70/351 (19%), Positives = 121/351 (34%), Gaps = 51/351 (14%) Query: 25 FTTTTVELRVPEGTNSVLVKNLYLSC---DPYMRI-RMGKPDPSTAALAQ-AYTPGQPIQ 79 + + P+G+ VL+K D +MR R G + T G I Sbjct: 13 LKLEDIPIPKPKGS-QVLIKIEAAGVCHSDVHMRQGRFGNLRIVEDLGVKLPVTLGHEIA 71 Query: 80 GYGVSRIIESGHPDYKKGDLLWGIVAWEEYSVITPMTHA--------------------- 118 G + Y KGDL+ + WE Sbjct: 72 GR--IEEVGDEVVGYSKGDLV-AVNPWEGEGNCYYCRIGEEHLCDSPRWLGINYDGAYAE 128 Query: 119 -----HFKIQHTDVPLSYYTGL-LGMPGMTAYAGFYEVCSPKEGETVYVSAASGAVGQLV 172 H+K + LS L G+T Y + S +T+ V A G +G + Sbjct: 129 YVLVPHYKYLYKLRRLSAVEAAPLTCSGVTTYRAVRK-ASLDPSKTLVVIGAGGGLGTMA 187 Query: 173 GQLAKMM-GCYVVGSAGSKEKVDLLKTKFGFDDAFNYKEESDLTAALKRCFPNGIDIYFE 231 Q+AK + G ++G +E ++ K + G D N + ++ + G D + Sbjct: 188 IQIAKAVSGATIIGVDVREEALEAAK-RAGADYVINASSQDPVSEIRRITQGKGADAVID 246 Query: 232 -NVGGKMLDAVLVNMNMHGRIAVCGMISQYNLENQEGVHNLSNIIYKRIRIQGFVVSDFY 290 N K L + G+ + G+ + ++ I ++ G +V + Sbjct: 247 LNNSEKTLSIYPYVLAKQGKYVMVGLF------GADLKYHAPLITLNEVQFIGSLVGNQS 300 Query: 291 DKYSKFLEFVLPHIREGKITYVEDVADGLEKAPEALVGLFHGKNVGKQVVV 341 D ++ GK+ + LE+A EA+ L + K VG+QV+V Sbjct: 301 D-----FLGIMSLAEAGKVKPMVTKTMKLEEANEAIDNLENFKAVGRQVLV 346 >3HZZ-A nrPDB Length = 467 Score = 101 bits (251), Expect = 5e-22, Method: Composition-based stats. Identities = 57/309 (18%), Positives = 99/309 (32%), Gaps = 43/309 (13%) Query: 65 TAALAQAYTPGQPIQGYGVSRIIES----GHPDYKKGDLLWGI----VAWEEYSVITPMT 116 T A+ PG + + +S +ES +WG E +++ Sbjct: 150 TGPGVNAWQPGDEVVAHCLSVELESPDGHDDTMLDPEQRIWGFETNFGGLAEIALVKTNQ 209 Query: 117 HAHFKIQHTDVPLSYYTGLLGMPGMTAYAGFYEV--CSPKEGETVYVSAASGAVGQLVGQ 174 + G+ TAY + K+G+ V + ASG +G Q Sbjct: 210 L----MPKPKHLTWEEAAAPGLVNSTAYRQLVSRNGAAMKQGDNVLIWGASGGLGSYATQ 265 Query: 175 LAKMMGCYVVGSAGSKEKVDLLKTKFGFDDAFNYKEES-----------------DLTAA 217 A G + S +K ++ ++ G + + E Sbjct: 266 FALAGGANPICVVSSPQKAEICRS-MGAEAIIDRNAEGYKFWKDEHTQDPKEWKRFGKRI 324 Query: 218 LKRCFPNGIDIYFENVGGKMLDAVLVNMNMHGRIAVCGMISQYNLENQEGVHNLSNIIYK 277 + IDI FE+ G + A + G I C S Y E ++ + Sbjct: 325 RELTGGEDIDIVFEHPGRETFGASVYVTRKGGTITTCASTSGYMHE-----YDNRYLWMS 379 Query: 278 RIRIQGFVVSDFYDKYSKFLEFVLPHIREGKITYVEDVADGLEKAPEALVGLFHGKNVGK 337 RI G +++ + Y I +GKI LE+ +A + + GK Sbjct: 380 LKRIIGSHFANYREAYEAN-----RLIAKGKIHPTLSKTYSLEETGQAAYDVHRNLHQGK 434 Query: 338 Q-VVVVARE 345 V+ +A E Sbjct: 435 VGVLCLAPE 443 >6N7L-A nrPDB Length = 353 Score = 98.4 bits (243), Expect = 4e-21, Method: Composition-based stats. Identities = 58/241 (24%), Positives = 90/241 (37%), Gaps = 22/241 (9%) Query: 104 VAWEEYSVITPMTHAHFKIQHTDVPLSYYTGLLGMPGMTAYAGFYEVCSPKEGETVYVSA 163 + EY + H K ++V +L G+T Y G E + K GE V +S Sbjct: 130 GGFAEYVIADSRYVGHLK---SNVNFLEIAPIL-CAGVTVYKGLKETET-KPGEWVAISG 184 Query: 164 ASGAVGQLVGQLAKMMGCYVVGSAGSKEKVDLLKTKFGFDDAFNYKEESDLTAALKRCFP 223 G +G + Q AK MG +V + +K++L K K G D N K T K Sbjct: 185 -IGGLGHVAVQYAKAMGMHVAAIDVADDKLELAK-KLGADLTVNAKTTDPGTYLHKEVG- 241 Query: 224 NGID-IYFENVGGKMLDAVLVNMNMHGRIAVCGMISQYNLENQEGVHNLSNIIYKRIRIQ 282 G+ V + + G IA+ G L + + KRI ++ Sbjct: 242 -GMHGALITAVSPIAFKQGIDVLRRKGTIALNG------LPPGSFELPIFETVLKRITVR 294 Query: 283 GFVVSDFYDKYSKFLEFVLPHIREGKITYVEDVADGLEKAPEALVGLFHGKNVGKQVVVV 342 G +V D L+ L EG + A LE + + G+ G+ V+ + Sbjct: 295 GSIVGTRKD-----LQEALDFANEGLVKATVTSAK-LEDINDVFDKMKKGQIDGRIVLDI 348 Query: 343 A 343 A Sbjct: 349 A 349 >4Z6K-A nrPDB Length = 346 Score = 97.6 bits (241), Expect = 7e-21, Method: Composition-based stats. Identities = 59/302 (19%), Positives = 94/302 (31%), Gaps = 51/302 (16%) Query: 69 AQAYTPGQPIQGYGVSRIIESGHPDYKKGDLL---W----------GIVAWEE------- 108 + + PG +G G+ + G K+GD + W + WE Sbjct: 54 SPPFIPGH--EGVGLITAVGEGVTHVKEGDRVGVAWLYSACGHCTHCLGGWETLCESQQN 111 Query: 109 ----------YSVITPMTHAHFKIQHTDVPLSYYTGLLGMPGMTAYAGFYEVCSPKEGET 158 V+ + + D S + G+T Y G K G+ Sbjct: 112 SGYSVNGSFAEYVLANANYVGIIPESVD---SIEIAPVLCAGVTVYKGLKMT-DTKPGDW 167 Query: 159 VYVSAASGAVGQLVGQLAKMMGCYVVGSAGSKEKVDLLKTKFGFDDAFNYKEESDLTAAL 218 V +S G +G + Q A MG V +K+ K K G N K Sbjct: 168 VVISG-IGGLGHMAVQYAIAMGLNVAAVDIDDDKLAFAK-KLGAKVTVNAKNTDPAEYLQ 225 Query: 219 KRCFPNGIDIYFENVGGKMLDAVLVNMNMHGRIAVCGMISQYNLENQEGVHNLSNIIYKR 278 K V K D L + G + G L + ++ + + Sbjct: 226 KEIGGA-HGALVTAVSAKAFDQALSMLRRGGTLVCNG------LPPGDFPVSIFDTVLNG 278 Query: 279 IRIQGFVVSDFYDKYSKFLEFVLPHIREGKITYVEDVADGLEKAPEALVGLFHGKNVGKQ 338 I I+G +V D L+ L GK+ A+ LE + + GK G+ Sbjct: 279 ITIRGSIVGTRLD-----LQESLDMAAAGKVKATVT-AEPLENINDIFERMRQGKIEGRI 332 Query: 339 VV 340 V+ Sbjct: 333 VI 334 >4EEZ-A nrPDB Length = 348 Score = 94.9 bits (234), Expect = 4e-20, Method: Composition-based stats. Identities = 54/293 (18%), Positives = 101/293 (34%), Gaps = 48/293 (16%) Query: 79 QGYGVSRIIESGHPDYKKGDLLWGIVAW------------------------EEYSVITP 114 +G G+ + I + + GD + VAW YSV Sbjct: 61 EGIGIVKEIGADVSSLQVGDRV--SVAWFFEGCGHCEYCVSGNETFCREVKNAGYSVDGG 118 Query: 115 MTHAHFKIQH-----TDVPLSYYTGLLGMPGMTAYAGFYEVCSPKEGETVYVSAASGAVG 169 M + D + G+T Y +V K G+ + A G +G Sbjct: 119 MAEEAIVVADYAVKVPDGLDPIEASSITCAGVTTYKAI-KVSGVKPGDWQVIFGA-GGLG 176 Query: 170 QLVGQLAKMM-GCYVVGSAGSKEKVDLLKTKFGFDDAFNYKEESDLTAALKRCFPNGIDI 228 L Q AK + G V+ +++K++L K K G D N + + + K G+ Sbjct: 177 NLAIQYAKNVFGAKVIAVDINQDKLNLAK-KIGADVTINSGDVNPVDEIKKITGGLGVQS 235 Query: 229 YFEN-VGGKMLDAVLVNMNMHGRIAVCGMISQYNLENQEGVHNLSNIIYKRIRIQGFVVS 287 V + + ++ G++ + N E ++ +++ + + G +V Sbjct: 236 AIVCAVARIAFEQAVASLKPMGKMVAVA------VPNTEMTLSVPTVVFDGVEVAGSLVG 289 Query: 288 DFYDKYSKFLEFVLPHIREGKITYVEDVADGLEKAPEALVGLFHGKNVGKQVV 340 D F EGK+ + LE+ + + + GK G+ V+ Sbjct: 290 TRLDLAEAF-----QFGAEGKVKPIVATRK-LEEINDIIDEMKAGKIEGRMVI 336 >3S2F-A nrPDB Length = 340 Score = 93.0 bits (229), Expect = 2e-19, Method: Composition-based stats. Identities = 71/348 (20%), Positives = 116/348 (33%), Gaps = 50/348 (14%) Query: 25 FTTTTVELRVPEGTNSVLVKNLYLSCDPYMRIRMGKPDPSTAALAQAYTPGQPI-QGYGV 83 T V + P G V VK + + P P +G G Sbjct: 15 LTIDEVPVPQP-GPGQVQVK-----IEASGVCHTDLHAADGDWPVKPTLPFIPGHEGVGY 68 Query: 84 SRIIESGHPDYKKGDLL---WGIV----------AWEE---------YSVITPMTHAHFK 121 + SG K+GD + W WE YSV Sbjct: 69 VSAVGSGVSRVKEGDRVGVPWLYSACGYCEHCLQGWETLCEKQQNTGYSVNGGYGEYVVA 128 Query: 122 IQHTDVPLSYYTGL-----LGMPGMTAYAGFYEVCSPKEGETVYVSAASGAVGQLVGQLA 176 + L G + G+T Y G +V + G+ V +S G +G + Q A Sbjct: 129 DPNYVGLLPDKVGFVEIAPILCAGVTVYKGL-KVTDTRPGQWVVISG-IGGLGHVAVQYA 186 Query: 177 KMMGCYVVGSAGSKEKVDLLKTKFGFDDAFNYKEESDLTAALKRCFPNGIDIYFENVGGK 236 + MG V K++L + + G + A N + ++D A L++ + V K Sbjct: 187 RAMGLRVAAVDIDDAKLNLAR-RLGAEVAVNAR-DTDPAAWLQKEIGGAHGVLVTAVSPK 244 Query: 237 MLDAVLVNMNMHGRIAVCGMISQYNLENQEGVHNLSNIIYKRIRIQGFVVSDFYDKYSKF 296 + + G IA+ G L + + +++ K I I+G +V D Sbjct: 245 AFSQAIGMVRRGGTIALNG------LPPGDFGTPIFDVVLKGITIRGSIVGTRSD----- 293 Query: 297 LEFVLPHIREGKITYVEDVADGLEKAPEALVGLFHGKNVGKQVVVVAR 344 L+ L G + A L+ + L GK G+ V+ +R Sbjct: 294 LQESLDFAAHGDVKATVSTAK-LDDVNDVFGRLREGKVEGRVVLDFSR 340 >4Y1B-A nrPDB Length = 425 Score = 92.6 bits (228), Expect = 2e-19, Method: Composition-based stats. Identities = 65/395 (16%), Positives = 123/395 (31%), Gaps = 92/395 (23%) Query: 16 GFPTESDFDFTTTTVELRVPEGTNSVLVKNLYLSCDPYMRI--RMGKPDPSTAALAQAYT 73 G P ++ F V P G VLVK + + Y + +G+P +A Sbjct: 52 GRPVDA-FRTEVVDVP---PVGPGQVLVKVMAAGVN-YNNVWAALGEP---LDVIAARQK 103 Query: 74 PGQP----IQGYGVSRIIESGHPD--YKKG----------------------------DL 99 G I G +S I+ + K G Sbjct: 104 QGATEDFHIGGSDLSGIVWAVGDGVRLKPGAEVVVLACRWDESAQDIRLGADPVTSSTQR 163 Query: 100 LWGI----VAWEEYSVITPMTHAHFKIQHTDVPLSYYTGLLGMP-GMTAYAGFY--EVCS 152 +WG ++ +++V+ + LS+ M TAY + E + Sbjct: 164 VWGYEENYGSFAQFAVVD-----EYMCHPKPQRLSWAAASCYMATAATAYRQLFGWEPHT 218 Query: 153 PKEGETVYVSAASGAVGQLVGQLAKMMGCYVVGSAGSKEKVDLLKTKFGFDDAFNYKEES 212 + G+ V + +G +G + QL + +G V S+E+ + + G + +E Sbjct: 219 VRPGDPVLIWGGAGGLGSIAIQLVRHVGGIPVAVVSSEERGEFC-MRLGAKGWIDRREFD 277 Query: 213 DLTAALKRCFPNGI------------------------DIYFENVGGKMLDAVLVNMNMH 248 + I E+ G + + + Sbjct: 278 HWGRLPDTTDEEAMKQWLDGARAFGRRFWEVLGERRAPRIVLEHSGADTIPTSIYMADNA 337 Query: 249 GRIAVCGMISQYNLENQEGVHNLSNIIYKRIRIQGFVVSDFYDKYSKFLEFVLPHIREGK 308 G + +CG + YN G +L + ++ R+QG + + + I +G Sbjct: 338 GMVVICGGTTGYN-----GDVDLRFLWMRQKRLQGSHAASAREARE-----ITRLIDQGA 387 Query: 309 ITYVEDVADGLEKAPEALVGLFHGKN-VGKQVVVV 342 I G E+ A + ++ G V+V Sbjct: 388 IDPCLSRTFGFEEIGLAHQLIHDNQHPSGNMAVLV 422 >4A10-A nrPDB Length = 447 Score = 92.6 bits (228), Expect = 2e-19, Method: Composition-based stats. Identities = 57/309 (18%), Positives = 89/309 (28%), Gaps = 43/309 (13%) Query: 65 TAALAQAYTPGQ--PIQGYGVSRIIESGHPDYKKGD--LLWGI----VAWEEYSVITPMT 116 T + + PG + V + H D G WG EY V+ Sbjct: 124 TGIGVRRWKPGDHVIVHPAHVDEQEPATHGDGMLGTEQRAWGFETNFGGLAEYGVVRASQ 183 Query: 117 HAHFKIQHTDVPLSYYTGLLGMPGMTAYAGFYEV--CSPKEGETVYVSAASGAVGQLVGQ 174 + + + TAY K+G+ V + ASG +G Q Sbjct: 184 L----LPKPAHLTWEEAAVSPLCAGTAYRMLVSDRGAQMKQGDIVLIWGASGGLGSYAIQ 239 Query: 175 LAKMMGCYVVGSAGSKEKVDLLKTKFGFDDAFNYKEESD-----------------LTAA 217 K G V S +K ++ G D N E L Sbjct: 240 FVKNGGGIPVAVVSSAQKEAAVR-ALGCDLVINRAELGITDDIADDPRRVVETGRKLAKL 298 Query: 218 LKRCFPNGIDIYFENVGGKMLDAVLVNMNMHGRIAVCGMISQYNLENQEGVHNLSNIIYK 277 + DI FE+ G ++ G + CG S Y + L + K Sbjct: 299 VVEKAGREPDIVFEHTGRVTFGLSVIVARRGGTVVTCGSSSGY--LHTFDNRYLWMKLKK 356 Query: 278 RIRIQGFVVSDFYDKYSKFLEFVLPHIREGKITYVEDVADGLEKAPEALVGLFHGKNVGK 337 +V + + + G + L +A EA + + VGK Sbjct: 357 -------IVGSHGANHEE-QQATNRLFESGAVVPAMSAVYPLAEAAEACRVVQTSRQVGK 408 Query: 338 Q-VVVVARE 345 V+ +A E Sbjct: 409 VAVLCMAPE 417 >4DVJ-A nrPDB Length = 363 Score = 92.2 bits (227), Expect = 3e-19, Method: Composition-based stats. Identities = 45/338 (13%), Positives = 106/338 (31%), Gaps = 29/338 (8%) Query: 18 PTESDFDFTTTTVELRVPEGTNSVLVKNLYLSCDPY-MRIRMGKPDPSTAALAQAYTPGQ 76 P D + P G + +LV+ +S +P ++R P T Y Sbjct: 33 PITDDASLLDIELPKPAPAG-HDILVEVKAVSVNPVDYKVRRSTPPDGTDWKVIGY---- 87 Query: 77 PIQGYGVSRIIESGHPDYKKGDLLWGIVAW---EEYSVITPMTHAHFKIQHTDVPLSYYT 133 G+ + ++ GD ++ + + + + + + Sbjct: 88 --DAAGIVSAVGPDVTLFRPGDEVFYAGSIIRPGTNAEFHLVDERIVGRKPKTLDWAEAA 145 Query: 134 GLLGMPGMTAYAGFYEVCSPK-----EGETVYVSAASGAVGQLVGQLAKMM-GCYVVGSA 187 L + +TA+ F++ + + +G VG + Q+A+ V+ +A Sbjct: 146 A-LPLTSITAWEAFFDRLDVNKPVPGAAPAILIVGGAGGVGSIAVQIARQRTDLTVIATA 204 Query: 188 GSKEKVDLLKTKFGFDDAFNYKEESDLTAALKRCFPNGIDIYFENVGGKMLDAVLVNMNM 247 E + +K+ G ++ + ++ K + + Sbjct: 205 SRPETQEWVKS-LGAHHVIDHSKP-LAAEVAALGLGAPAFVFSTTHTDKHAAEIADLIAP 262 Query: 248 HGRIAVCGMISQYNLE--NQEGVHNLSNIIYKRIRIQGFVVSDFYDKYSKFLEFVLPHIR 305 GR + S +++ ++ V +++ R +S+ + L V + Sbjct: 263 QGRFCLIDDPSAFDIMLFKRKAVSIHHELMFTRPMFGTPDMSEQG----RLLNDVSRLVD 318 Query: 306 EGKITYVEDVADG---LEKAPEALVGLFHGKNVGKQVV 340 EG++ +A + G GK V+ Sbjct: 319 EGRLRTTLTNRLSPINAANLKQAHALVESGTARGKVVI 356 >4IDE-A nrPDB Length = 332 Score = 91.8 bits (226), Expect = 4e-19, Method: Composition-based stats. Identities = 80/359 (22%), Positives = 131/359 (36%), Gaps = 68/359 (18%) Query: 1 MTATNKQVILKDYVSGFPTESDFDFTTTTVELRVPE-GTNSVLVKNLYLSCDPYMRIRMG 59 + + NK + +Y T F + + VPE + VL+K + S +P Sbjct: 20 IPSVNKAWVYSEY---GKTSDVLKFDPS---VAVPEIKEDQVLIKVVAASLNPV------ 67 Query: 60 KPDPSTAALAQAYTPGQPIQGYGVSRI---IESGHPDYKKGDLLWG------------IV 104 + +P I GY V+ + + S +K GD ++G Sbjct: 68 DFKRALGYFKDTDSPLPTIPGYDVAGVVVKVGSQVTKFKVGDEVYGDLNETALVNPTRFG 127 Query: 105 AWEEYSVITPMTHAHFKIQHTDVPLSYYTGLLGMPGMTAYAGFYEVCSPKEGETVYVSAA 164 + EY+ AH + + L + TA+ G E G++V V Sbjct: 128 SLAEYTAADERVLAHKPKNLSFIE----AASLPLAIETAHEGL-ERAELSAGKSVLVLGG 182 Query: 165 SGAVGQLVGQLAKMM-GCYVVGSAGSKEKVDLLKTKFGFDDAFNYKEESDLTAALKRCFP 223 +G VG + QLAK + G V + S +K+DLL+T G D A +Y +E+ K Sbjct: 183 AGGVGTHIIQLAKHVFGASKVAATASTKKLDLLRT-LGADLAIDYTKENFEDLPEKF--- 238 Query: 224 NGIDIYFENVGGKMLDAVLVNMNMHGRIAVCGMISQYNLENQEGVHNLSNIIYKRIRIQG 283 D+ ++ VG D + + G++ G I+ Sbjct: 239 ---DVVYDAVGET--DKAVKAVKEGGKVVTI-----------VGPATPPAIL-------- 274 Query: 284 FVVSDFYDKYSKFLEFVLPHIREGKITYVED--VADGLEKAPEALVGLFHGKNVGKQVV 340 FV++ LE + P++ GK+ V D K EA L + GK VV Sbjct: 275 FVLTSKGSV----LEKLKPYLESGKVKPVLDPTSPYPFTKVVEAFGYLESSRATGKVVV 329 >1H2B-A nrPDB Length = 359 Score = 90.7 bits (223), Expect = 9e-19, Method: Composition-based stats. Identities = 49/303 (16%), Positives = 103/303 (33%), Gaps = 50/303 (16%) Query: 71 AYTPGQPIQGYGVSRIIESGHPDYKKGDLLWGIVAWEEYSVITPMTHAHFKIQ------- 123 YT G GY + G +KGD + A + + + + Sbjct: 74 PYTLGHENVGY--IEEVAEGVEGLEKGDPVILHPAVTDGTCLACRAGEDMHCENLEFPGL 131 Query: 124 --------------------HTDVPLSYYTGLLGMP--GMTAYAGFYEVC-SPKEGETVY 160 D+ + + G+TAY + + G V Sbjct: 132 NIDGGFAEFMRTSHRSVIKLPKDISREKLVEMAPLADAGITAYRAVKKAARTLYPGAYVA 191 Query: 161 VSAASGAVGQLVGQLAK-MMGCYVVGSAGSKEKVDLLKTKFGFDDAFNYKEESDLTAALK 219 + G +G + QL K M V+ +EK+ L + G D + + + + ++ Sbjct: 192 IVGV-GGLGHIAVQLLKVMTPATVIALDVKEEKLK-LAERLGADHVVDARRDP-VKQVME 248 Query: 220 RCFPNGIDIYFENVGG-KMLDAVLVNMNMHGRIAVCGMISQYNLENQEGVHNLSNIIYKR 278 G+++ + VG +D + GR+ + G L +I Sbjct: 249 LTRGRGVNVAMDFVGSQATVDYTPYLLGRMGRLIIVGY--GGELRFPTI-----RVISSE 301 Query: 279 IRIQGFVVSDFYDKYSKFLEFVLPHIREGKITYVEDVADGLEKAPEALVGLFHGKNVGKQ 338 + +G +V ++ + + ++ +GK+ D L++ + L L G+ +G+ Sbjct: 302 VSFEGSLVGNYVELHE-----LVTLALQGKVRVEVD-IHKLDEINDVLERLEKGEVLGRA 355 Query: 339 VVV 341 V++ Sbjct: 356 VLI 358 >1R37-A nrPDB Length = 347 Score = 84.9 bits (208), Expect = 5e-17, Method: Composition-based stats. Identities = 59/300 (19%), Positives = 104/300 (34%), Gaps = 45/300 (15%) Query: 71 AYTPGQPIQGYGVSRIIESGHPDYKKGDLLWGIVAWEEYSVITPMTHA------------ 118 T G I G + Y KGDL+ + W+ Sbjct: 63 PVTLGHEIAGK--IEEVGDEVVGYSKGDLV-AVNPWQGEGNCYYCRIGEEHLCDSPRWLG 119 Query: 119 --------------HFKIQHTDVPLSYYTGL-LGMPGMTAYAGFYEVCSPKEGETVYVSA 163 H+K + L+ L G+T Y + S +T+ V Sbjct: 120 INFDGAYAEYVIVPHYKYMYKLRRLNAVEAAPLTCSGITTYRAVRK-ASLDPTKTLLVVG 178 Query: 164 ASGAVGQLVGQLAKMM-GCYVVGSAGSKEKVDLLKTKFGFDDAFNYKEESDLTAALKRCF 222 A G +G + Q+AK + G ++G +E V+ K + G D N + L + Sbjct: 179 AGGGLGTMAVQIAKAVSGATIIGVDVREEAVEAAK-RAGADYVINASMQDPLAEIRRITE 237 Query: 223 PNGIDIYFE-NVGGKMLDAVLVNMNMHGRIAVCGMISQYNLENQEGVHNLSNIIYKRIRI 281 G+D + N K L + G+ + G+ + ++ I I+ Sbjct: 238 SKGVDAVIDLNNSEKTLSVYPKALAKQGKYVMVGLF------GADLHYHAPLITLSEIQF 291 Query: 282 QGFVVSDFYDKYSKFLEFVLPHIREGKITYVEDVADGLEKAPEALVGLFHGKNVGKQVVV 341 G +V + D ++ GK+ + LE+A EA+ L + K +G+QV++ Sbjct: 292 VGSLVGNQSD-----FLGIMRLAEAGKVKPMITKTMKLEEANEAIDNLENFKAIGRQVLI 346 >4CPD-A nrPDB Length = 347 Score = 81.0 bits (198), Expect = 6e-16, Method: Composition-based stats. Identities = 46/205 (22%), Positives = 85/205 (41%), Gaps = 19/205 (9%) Query: 142 TAYAGFYEVCSPKEGETVYVSAASGAVGQLVGQLAKMMGC-YVVGSAGSKEKVDLLKTKF 200 TAY G + + G++V V A G VG + ++A+++G ++ E+++ + Sbjct: 156 TAYGGLIQ-GQLRPGDSVAVIGA-GPVGLMAIEVAQVLGASKILAIDRIPERLERAAS-L 212 Query: 201 GFDDAFNYKEESDLTAALKRCFPNGIDIYFENVGG-KMLDAVLVNMNMHGRIAVCGMISQ 259 G N ++E+ + G D+ E VGG L L + GR++ G+ + Sbjct: 213 GA-IPINAEQENPVRRVRSETNDEGPDLVLEAVGGAATLSLALEMVRPGGRVSAVGVDNA 271 Query: 260 YNLENQEGVHNLSNIIYKRIRIQGFVVSDFYDKYSKFLEFVLPHIREGKITYVEDVAD-- 317 + + ++ + RI V + D VL + G++ V+ Sbjct: 272 PSFPFPLASGLVKDLTF---RIGLANVHLYIDA-------VLALLASGRLQPERIVSHYL 321 Query: 318 GLEKAPEALVGLFHGKNVGKQVVVV 342 LE+AP LF K K ++VV Sbjct: 322 PLEEAPRGYE-LFDRKEALKVLLVV 345 >5GXF-A nrPDB Length = 330 Score = 80.3 bits (196), Expect = 1e-15, Method: Composition-based stats. Identities = 54/276 (19%), Positives = 87/276 (31%), Gaps = 25/276 (9%) Query: 78 IQGYGVSRIIE-SGHPDYKKGDLLW------GIVAWEEYSVITPMTHAHFKIQHTDVPLS 130 + G + +E S YK GD + G W YS A + + + + Sbjct: 63 VPGIDFAGTVENSSDERYKPGDKVVLTGWRVGEAHWGGYS-QKANVRADWLVPLPEGLDT 121 Query: 131 YYTGLLGMPGMTAYAGFY--EVCSPKEGET-VYVSAASGAVGQLVGQLAKMMGCYVVGSA 187 +G G TA E G V V+ A+G VG + + +G V Sbjct: 122 RQAMAVGTAGFTAMLAVMALEDHGLTPGHGPVLVTGAAGGVGSVATAILAHLGYEVAAVT 181 Query: 188 GSKEKVDLLKTKFGFDDAFNYKE--ESDLTAALKRCFPNGIDIYFENVGGKMLDAVLVNM 245 G E D L + G E E+ + +D VGG ML VL M Sbjct: 182 GRPETADYLTS-LGATQIVARDEINETVKRPLESEIWAGCVDA----VGGAMLARVLGQM 236 Query: 246 NMHGRIAVCGMISQYNLENQEGVHNLSNIIYKRIRIQGFV-VSDFYDKYSKFLEFVLPHI 304 + + + + + + + G V Y + E + + Sbjct: 237 KYG-----ASVAAVGLAGGAGLPATVIPFLLRGVNLLGIDSVMQPYANRLRAWERIARDL 291 Query: 305 REGKITYVEDVADGLEKAPEALVGLFHGKNVGKQVV 340 K+ + A L P + G+ G+ VV Sbjct: 292 PMDKLEAMIRPA-TLSDLPGLGADILKGQVQGRVVV 326 >2DFV-A nrPDB Length = 347 Score = 79.5 bits (194), Expect = 2e-15, Method: Composition-based stats. Identities = 72/358 (20%), Positives = 123/358 (34%), Gaps = 55/358 (15%) Query: 19 TESDFDFTTTTVELRVPEGTNSVLVKNLYLSCDPYMRIRMGKPDPSTAALAQ-AYTPGQP 77 T+ + V++ P G VL+K L S AQ P Q Sbjct: 10 TKPGYGAELVEVDVPKP-GPGEVLIKVLATSI-----CGTDLHIYEWNEWAQSRIKPPQI 63 Query: 78 IQGYGVSRIIESG--HPDYKKGDLLWGIVAWEEYSVITPM-----------THAHFKIQH 124 + ++E G + GD + + E + V + Sbjct: 64 MGHEVAGEVVEIGPGVEGIEVGDYV----SVETHIVCGKCYACRRGQYHVCQNTKIFGVD 119 Query: 125 TDVPLSYYTGLLGMPGMTA-------YAGFYE---------VCSPKEGETVYVSAASGAV 168 TD + Y + YA E + P G++V ++ A G + Sbjct: 120 TDGVFAEYAVVPAQNIWKNPKSIPPEYATLQEPLGNAVDTVLAGPISGKSVLITGA-GPL 178 Query: 169 GQLVGQLAKMMGCYVVGSAGSKEKVDLLKTKFGFDDAFNYKEESDLTAALKRCFPNGIDI 228 G L +AK G Y V + + L K G D N EE + + NG+D+ Sbjct: 179 GLLGIAVAKASGAYPVIVSEPSDFRRELAKKVGADYVINPFEEDVVKEVMDITDGNGVDV 238 Query: 229 YFENVGG-KMLDAVLVNMNMHGRIAVCGMISQYNLENQEGVHNLSNIIYKRIRIQGFVVS 287 + E G K L+ L + GR+++ G+ + + + II+K + I G Sbjct: 239 FLEFSGAPKALEQGLQAVTPAGRVSLLGLY-----PGKVTIDFNNLIIFKALTIYGITGR 293 Query: 288 DFYDKYSKFLEFVLPHIREGKIT---YVEDVADGLEKAPEALVGLFHGKNVGKQVVVV 342 ++ + V ++ GK+ + G +K EA + GK GK V ++ Sbjct: 294 HLWETWYT----VSRLLQSGKLNLDPIITHKYKGFDKYEEAFELMRAGK-TGKVVFML 346 >4GKV-A nrPDB Length = 336 Score = 78.3 bits (191), Expect = 4e-15, Method: Composition-based stats. Identities = 53/292 (18%), Positives = 91/292 (31%), Gaps = 48/292 (16%) Query: 79 QGYGVSRIIESGHPDYKKGDLLWGIVAW------------------------EEYSVITP 114 +G GV + G K GD VAW YSV Sbjct: 59 EGIGVVAEVGPGVTSLKPGDR--ASVAWFYEGCGHCEYCNSGNETLCRSVKNAGYSVDGG 116 Query: 115 MTH-----AHFKIQHTDVPLSYYTGLLGMPGMTAYAGFYEVCSPKEGETVYVSAASGAVG 169 M A + ++ D S + G+T Y ++ + G+ + + G Sbjct: 117 MAEECIVVADYAVKVPDGLDSAAASSITCAGVTTYKAV-KLSKIRPGQWIAIYGLGGLG- 174 Query: 170 QLVGQLAKMM-GCYVVGSAGSKEKVDLLKTKFGFDDAFNYKEESDLTAALKRCFPNGIDI 228 L Q AK + V+ + E++ L T+ G D A N E ++ Sbjct: 175 NLALQYAKNVFNAKVIAIDVNDEQLK-LATEMGADLAINSHTEDAAKIVQEKTGGAHA-A 232 Query: 229 YFENVGGKMLDAVLVNMNMHGRIAVCGMISQYNLENQEGVHNLSNIIYKRIRIQGFVVSD 288 V ++ + + GR+ G L + ++ ++ I + G +V Sbjct: 233 VVTAVAKAAFNSAVDAVRAGGRVVAVG------LPPESMSLDIPRLVLDGIEVVGSLVGT 286 Query: 289 FYDKYSKFLEFVLPHIREGKITYVEDVADGLEKAPEALVGLFHGKNVGKQVV 340 D F EGK+ + L + GK G+ V+ Sbjct: 287 RQDLTEAF-----QFAAEGKVVPKVALR-PLADINTIFTEMEEGKIRGRMVI 332 >3FPC-A nrPDB Length = 352 Score = 76.8 bits (187), Expect = 1e-14, Method: Composition-based stats. Identities = 53/296 (17%), Positives = 102/296 (34%), Gaps = 40/296 (13%) Query: 83 VSRIIESGH--PDYKKGDLLWG-----------------------IVAWEEYSVITPMTH 117 V ++E G D+K GD + + W+ +V + Sbjct: 62 VGEVVEVGSEVKDFKPGDRVVVPAITPDWRTSEVQRGYHQHSGGMLAGWKFSNVKDGVFG 121 Query: 118 AHFKIQHTDVPLSYYTGLLGMPG-------MTAYAGFYEVCSPKEGETVYVSAASGAVGQ 170 F + D+ L++ + + MT E+ + K G+TV V G VG Sbjct: 122 EFFHVNDADMNLAHLPKEIPLEAAVMIPDMMTTGFHGAELANIKLGDTVCVIG-IGPVGL 180 Query: 171 LVGQLAKMMGCYVVGSAGSKEKVDLLKTKFGFDDAFNYKEESDLTAALKRCFPNGIDIYF 230 + A +G + + GS++ + ++G D NYK + LK G+D Sbjct: 181 MSVAGANHLGAGRIFAVGSRKHCCDIALEYGATDIINYKNGDIVEQILKATDGKGVDKVV 240 Query: 231 ENVGGK--MLDAVLVNMNMHGRIAVCGMISQYNLENQEGVHNLSNIIYKRIRIQGFVVSD 288 GG + + I + + +N + + + I G + Sbjct: 241 -IAGGDVHTFAQAVKMIKPGSDIGNVNYLGEG--DNIDIPRSEWGVGMGHKHIHGGLCPG 297 Query: 289 FYDKYSKFLEFVLPHIREGKITYVEDVADGLEKAPEALVGL-FHGKNVGKQVVVVA 343 + L ++ + R V V G + +A + + K++ K VV++A Sbjct: 298 -GRLRMERLIDLVFYKRVDPSKLVTHVFRGFDNIEKAFMLMKDKPKDLIKPVVILA 352 >3GFB-A nrPDB Length = 350 Score = 76.4 bits (186), Expect = 1e-14, Method: Composition-based stats. Identities = 67/346 (19%), Positives = 115/346 (33%), Gaps = 49/346 (14%) Query: 24 DFTTTTVELRVPEGTNSVLVKNLYLSCDPYMRIRMGKPDPSTAALAQ-AYTPGQPIQGYG 82 + V P VL+K L S AQ P Q + Sbjct: 18 ELVEVDVPKPGP---GEVLIKVLATSI-----CGTDLHIYEWNEWAQSRIKPPQIMGHEV 69 Query: 83 VSRIIESG--HPDYKKGD-------LLWGIVAWEEYSVITPMTHAHFKIQHTDVPLSYYT 133 ++E G D + GD ++ G +++ + D ++Y Sbjct: 70 AGEVVEVGPGVEDLQVGDYISVETHIVCGKCYACKHNRYHVCQNTKIFGVDMDGVFAHYA 129 Query: 134 GLLGMPGMTA-------YAGFYE---------VCSPKEGETVYVSAASGAVGQLVGQLAK 177 + YA E + P G + ++ A G +G L +AK Sbjct: 130 IVPAKNAWKNPKDMPPEYAALQEPLGNAVDTVLAGPIAGRSTLITGA-GPLGLLGIAVAK 188 Query: 178 MMGCYVVGSAGSKEKVDLLKTKFGFDDAFNYKEESDLTAALKRCFPNGIDIYFENVGG-K 236 G Y V + E L K G D N EE + + G++++ E G K Sbjct: 189 ASGAYPVIVSEPSEFRRKLAKKVGADYVVNPFEEDPVKFVMDITDGAGVEVFLEFSGAPK 248 Query: 237 MLDAVLVNMNMHGRIAVCGMISQYNLENQEGVHNLSNIIYKRIRIQGFVVSDFYDKYSKF 296 L+ L + GR+++ G+ + + + II+K + + G ++ + Sbjct: 249 ALEQGLKAVTPGGRVSLLGL-----FPREVTIDFNNLIIFKALEVHGITGRHLWETWYT- 302 Query: 297 LEFVLPHIREGKIT---YVEDVADGLEKAPEALVGLFHGKNVGKQV 339 V I+ GK+ + G +K EA + GK GK V Sbjct: 303 ---VSSLIQSGKLNLDPIITHKYKGFDKFEEAFELMRAGK-TGKVV 344 >4OH1-A nrPDB Length = 351 Score = 76.4 bits (186), Expect = 2e-14, Method: Composition-based stats. Identities = 44/241 (18%), Positives = 79/241 (32%), Gaps = 19/241 (7%) Query: 105 AWEEYSVITPMTHAHFKIQHTDVPLSYYTGLLGMPGMTAYAGFYEVCSPKEGETVYVSAA 164 + EY+V + D L Y + +T E G++V + A Sbjct: 129 GFSEYAVYH---MSQIFPIPDDADLKDYA---LVEPLTVALSSAEQAKISYGKSVAIMGA 182 Query: 165 SGAVGQLVGQLAKMMGCYVVGSAGSKEKVDLLKTKFGFDDAFNYKEESDLTAALKRCFPN 224 G +G ++ QLA++ G + + L + G D A N EE A++ Sbjct: 183 -GGLGMMLVQLARLAGASTITVFDIVPEKLELALENGADYALNSAEEGVAERAIELAGGR 241 Query: 225 GIDIYFENVGGKMLDAV-LVNMNMHGRIAVCGMISQYNLENQEGVHNLSNIIYKRIRIQG 283 D E G + L + G M Y + V+ S++ + + I G Sbjct: 242 -YDCVLEGTGATAAAKLGLQLLARDGDAVYFAM---YGKDPILPVNLQSDLYWDQKHIHG 297 Query: 284 FVVSDFYDKYSKFLEFVLPHIREGKITYVEDVADGLEKAPEALVGLFHGKNVGKQVVVVA 343 + + S + I + + L +A L+ K K V+ + Sbjct: 298 MIQGAWQFPKS------IRMIPRMDFSKIIQKEHTLTNYKQAFEDLYS-KKYAKIVIKMD 350 Query: 344 R 344 Sbjct: 351 E 351 >5VM2-A nrPDB Length = 347 Score = 74.9 bits (182), Expect = 5e-14, Method: Composition-based stats. Identities = 51/349 (14%), Positives = 102/349 (29%), Gaps = 44/349 (12%) Query: 25 FTTTTVELRVPEGTNSVLVKNLYLSC-----------------DPYMRIRMGKPDPST-- 65 + E+ VP + VL+K Y+ DP I +G T Sbjct: 14 MKIISAEIPVP-KEDEVLIKVEYVGICGSDVHGFESGPFIPPKDPNQEIGLGHECAGTVV 72 Query: 66 --AALAQAYTPGQPI------QGYGVSRIIESGHPDYKKGDLLWGIVAWEEYSVITPMTH 117 + + + PG + +E + D + + Sbjct: 73 AVGSRVRKFKPGDRVNIEPGVPCGHCRYCLEGKYNICPDVDFMATQPNYRGALTHYLCHP 132 Query: 118 AHFKIQHTDVPLSYYTGLLGMPGMTAYAGFYEVCSPKEGETVYVSAASGAVGQLVGQLAK 177 F + D + G L P + K G+ + + A G +G + Q K Sbjct: 133 ESFTYKLPD-NMDTMEGTLVEPAAVGMHAAM-LADVKPGKKIIILGA-GCIGLMTLQACK 189 Query: 178 MMGCYVVGSAGSKEKVDLLKTKFGFDDAFNYKEESDLTAALKRCFPNGIDIYFENVGGKM 237 +G + EK + + G N +E + + G DI FE G + Sbjct: 190 CLGATEIAVVDVLEKRLAMAEQLGATVVINGAKEDTIARCQQFTEDMGADIVFETAGSAV 249 Query: 238 LDAVLVNMN-MHGRIAVCGMISQYNLENQEGVHNLSNIIYKRIRIQGFVVSDFYDKYSKF 296 + G+I + G + + N + + V + ++Y Sbjct: 250 TVKQAPYLVMRGGKIMIVGTVPG---------ASAINFLKINREVTIQTVFRYANRYPVT 300 Query: 297 LEFVLPHIREGKITYVEDVADGLEKAPEALVGLFHGK-NVGKQVVVVAR 344 +E + + + +A + K ++ K V+ ++ Sbjct: 301 IEAISSG--RFDVKSMVTHIYDYRDVQQAFEESVNNKRDIIKGVIKISD 347 >3FSR-A nrPDB Length = 352 Score = 72.9 bits (177), Expect = 2e-13, Method: Composition-based stats. Identities = 54/295 (18%), Positives = 101/295 (34%), Gaps = 38/295 (12%) Query: 83 VSRIIESGH--PDYKKGDLLWG-----------------------IVAWEEYSVITPMTH 117 V ++E G D+K GD + + W+ +V + Sbjct: 62 VGEVVEVGSEVKDFKPGDRVVVPAITPDWRTSEVQRGYHQHSGGMLAGWKFSNVKDGVFG 121 Query: 118 AHFKIQHTDVPLSYYTGLLGMPG-------MTAYAGFYEVCSPKEGETVYVSAASGAVGQ 170 F + D+ L++ + + MT E+ + G +V V GAVG Sbjct: 122 EFFHVNDADMNLAHLPKEIPLEAAVMIPDMMTTGFHGAELADIQMGSSVVVIG-IGAVGL 180 Query: 171 LVGQLAKMMGCYVVGSAGSKEKVDLLKTKFGFDDAFNYKEESDLTAALKRCFPNGID-IY 229 + AK+ G + GS+ +G D NYK + +K G+D + Sbjct: 181 MGIAGAKLRGAGRIIGVGSRPICVEAAKFYGATDILNYKNGHIVDQVMKLTNGKGVDRVI 240 Query: 230 FENVGGKMLDAVLVNMNMHGRIAVCGMISQYNLENQEGVHNLSNIIYKRIRIQGFVVSDF 289 G + L + + G I+ + V + +K I+G + Sbjct: 241 MAGGGSETLSQAVSMVKPGGIISNINYHGSGDALLIPRVEWGCGMAHK--TIKGGLCPG- 297 Query: 290 YDKYSKFLEFVLPHIREGKITYVEDVADGLEKAPEALVGL-FHGKNVGKQVVVVA 343 + L ++ + R V V G + +A + + K++ K VV++A Sbjct: 298 GRLRMERLIDLVFYKRVDPSKLVTHVFRGFDNIEKAFMLMKDKPKDLIKPVVILA 352 >1HSO-A nrPDB Length = 374 Score = 72.2 bits (175), Expect = 3e-13, Method: Composition-based stats. Identities = 47/241 (19%), Positives = 81/241 (33%), Gaps = 19/241 (7%) Query: 101 WGIVAWEEYSVITPMTHAHFKIQHTDVPLSYYTGLLGMPGMTAYAGFYEVCSPKEGETVY 160 GI + +Y+V+ A PL L+G T Y V G T Sbjct: 141 LGISTFSQYTVVDENAVAKIDAAS---PLEKVC-LIGCGFSTGYGSAVNVAKVTPGSTCA 196 Query: 161 VSAASGAVGQLVGQLAKMMG-CYVVGSAGSKEKVDLLKTKFGFDDAFN---YKEESDLTA 216 V G VG K G ++ +K+K K + G + N YK+ + Sbjct: 197 VFG-LGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAK-ELGATECINPQDYKKP--IQE 252 Query: 217 ALKRCFPNGIDIYFENVG--GKMLDAVLVNMNMHGRIAVCGMISQYNLENQEGVHNLSNI 274 LK G+D FE +G M+ ++L G + G+ + + + + Sbjct: 253 VLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVP-----PDSQNLSMNPML 307 Query: 275 IYKRIRIQGFVVSDFYDKYSKFLEFVLPHIREGKITYVEDVADGLEKAPEALVGLFHGKN 334 + +G ++ F K ++ + + EK E L GK+ Sbjct: 308 LLTGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLHSGKS 367 Query: 335 V 335 + Sbjct: 368 I 368 >3COS-A nrPDB Length = 381 Score = 72.2 bits (175), Expect = 3e-13, Method: Composition-based stats. Identities = 48/264 (18%), Positives = 85/264 (32%), Gaps = 19/264 (7%) Query: 85 RIIESGHPDYK-KGDLL---WGIVAWEEYSVITPMTHAHFKIQHTDVPLSYYTGLLGMPG 140 +++E + KG + +G + +Y+V++ + A D L LLG Sbjct: 128 QLMEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKID---DDANLERVC-LLGCGF 183 Query: 141 MTAYAGFYEVCSPKEGETVYVSAASGAVGQLVGQLAKMMGC-YVVGSAGSKEKVDLLKTK 199 T Y G T V G VG K G ++G + EK K Sbjct: 184 STGYGAAINNAKVTPGSTCAVFG-LGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAK-A 241 Query: 200 FGFDDAFNYKE-ESDLTAALKRCFPNGIDIYFENVGG-KMLDAVLVNMNMH-GRIAVCGM 256 G D N ++ + + G+D + GG + + A L G G+ Sbjct: 242 LGATDCLNPRDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGV 301 Query: 257 ISQYNLENQEGVHNLSNIIYKRIRIQGFVVSDFYDKYSKFLEFVLPHIREGKITYVEDVA 316 + V II + I G + S ++ + + Sbjct: 302 AAG---SKGLTVFPEELIIGR--TINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHT 356 Query: 317 DGLEKAPEALVGLFHGKNVGKQVV 340 +K EA + GK++ ++ Sbjct: 357 LPFDKISEAFDLMNQGKSIRTILI 380 >4EJ6-A nrPDB Length = 370 Score = 72.2 bits (175), Expect = 3e-13, Method: Composition-based stats. Identities = 43/245 (17%), Positives = 87/245 (35%), Gaps = 19/245 (7%) Query: 104 VAWEEYSVITPMTHAHFKIQHTDVPLSYYTGLLGMPGMTAYAGFYEVCSPKEGETVYVSA 163 + EY ++ + V ++ L G ++ K G TV + Sbjct: 137 GGFAEYVLVPRKQAFEIPLTLDPVHGAFCEPLACC-----LHGV-DLSGIKAGSTVAILG 190 Query: 164 ASGAVGQLVGQLAKMMGCYVVGSAGSKEKVDLLKTKFGFDDAFNYKEESDLTAALKRCF- 222 G +G L QLA++ G V + + L + G + + A Sbjct: 191 G-GVIGLLTVQLARLAGATTVILSTRQATKRRLAEEVGATATVDPSAGDVVEAIAGPVGL 249 Query: 223 -PNGIDIYFENVG-GKMLDAVLVNMNMHGRIAVCGMISQYNLENQEGVHNLSNIIYKRIR 280 P G+D+ E G + + G + + G++ Q E +I+++ +R Sbjct: 250 VPGGVDVVIECAGVAETVKQSTRLAKAGGTVVILGVLPQGEKVEIE----PFDILFRELR 305 Query: 281 IQGFVVSDFYDKYSKFLEFVLPHIREGKITYVEDVADGLEKAPEALVGLFHGKNVGKQVV 340 + G ++ F + + + V E I + L++AP+ + V K +V Sbjct: 306 VLGSFINPF--VHRRAADLVATGAIE--IDRMISRRISLDEAPDVISNPAAAGEV-KVLV 360 Query: 341 VVARE 345 + + E Sbjct: 361 IPSAE 365 >5TNX-A nrPDB Length = 383 Score = 71.4 bits (173), Expect = 5e-13, Method: Composition-based stats. Identities = 44/260 (16%), Positives = 83/260 (31%), Gaps = 18/260 (6%) Query: 75 GQPIQGYGVSRIIESGHPDYKKGDLLWGIVAWEEYSVITPMTHAHFKIQHTDVPLSYYTG 134 G G R D + ++ Y++ + G Sbjct: 129 GADADGQTALR----DAAGEPLHDHFFAQSSFASYALARENNAIKVPKEAPL----ELLG 180 Query: 135 LLGMPGMTAYAGFYEVCSPKEGETVYVSAASGAVGQLVGQLAKMMGCYVVGSAGSKEKVD 194 LG T + + G + A GAVG A++ G + + Sbjct: 181 PLGCGIQTGAGAVINSLAVRTGSSFASFGA-GAVGMSAVMAARIAGATTIIAVDIVPSRL 239 Query: 195 LLKTKFGFDDAFNYKEESDLTAALKRCFPNGIDIYFENVG-GKMLDAVLVNMNMHGRIAV 253 L + G A N KE D+ A++ G+D E+ G +L + + G + V Sbjct: 240 ALALELGATHAINSKEV-DVVDAIREITGGGVDYALESTGLPAVLSQGIDALGSRGTMGV 298 Query: 254 CGMISQYNLENQEGVHNLSNIIYKRIRIQGFVVSDFYDKYSKFLEFVLPHIREGKITYVE 313 G + ++++++ I+G V D F+ ++ +G+ + Sbjct: 299 VGAPKL----GTKAEFDVNSLLLGGHTIRGIVEGDSVP--QTFIPQLVQLHLQGRFPFDR 352 Query: 314 DVA-DGLEKAPEALVGLFHG 332 V LE+ +A G Sbjct: 353 LVKFYPLEQINQAAADSSSG 372 >1KEV-A nrPDB Length = 351 Score = 71.4 bits (173), Expect = 6e-13, Method: Composition-based stats. Identities = 54/294 (18%), Positives = 101/294 (34%), Gaps = 38/294 (12%) Query: 83 VSRIIESGH--PDYKKGDLLWG-----------------------IVAWEEYSVITPMTH 117 V ++E G D+K GD + + W+ + + Sbjct: 62 VGEVVEVGSEVKDFKPGDRVIVPCTTPDWRSLEVQAGFQQHSNGMLAGWKFSNFKDGVFG 121 Query: 118 AHFKIQHTDVPLSYYTGLLGMPG-------MTAYAGFYEVCSPKEGETVYVSAASGAVGQ 170 +F + D+ L+ + + MT E+ + G +V V GAVG Sbjct: 122 EYFHVNDADMNLAILPKDMPLENAVMITDMMTTGFHGAELADIQMGSSVVVIG-IGAVGL 180 Query: 171 LVGQLAKMMGCYVVGSAGSKEKVDLLKTKFGFDDAFNYKEESDLTAALKRCFPNGID-IY 229 + AK+ G + GS+ +G D NYK + +K G+D + Sbjct: 181 MGIAGAKLRGAGRIIGVGSRPICVEAAKFYGATDILNYKNGHIVDQVMKLTNGKGVDRVI 240 Query: 230 FENVGGKMLDAVLVNMNMHGRIAVCGMISQYNLENQEGVHNLSNIIYKRIRIQGFVVSDF 289 G + L + + G I+ + V + +K I+G + Sbjct: 241 MAGGGSETLSQAVSMVKPGGIISNINYHGSGDALLIPRVEWGCGMAHK--TIKGGLCPG- 297 Query: 290 YDKYSKFLEFVLPHIREGKITYVEDVADGLEKAPEALVGL-FHGKNVGKQVVVV 342 ++ L ++ + R V V G + EAL+ + K++ K VV++ Sbjct: 298 GRLRAEMLRDMVVYNRVDLSKLVTHVYHGFDHIEEALLLMKDKPKDLIKAVVIL 351 >1HSZ-A nrPDB Length = 374 Score = 71.0 bits (172), Expect = 7e-13, Method: Composition-based stats. Identities = 49/249 (19%), Positives = 85/249 (34%), Gaps = 24/249 (9%) Query: 101 WGIVAWEEYSVITPMTHAHFKIQHTDVPLSYYTGLLGMPGMTAYAGFYEVCSPKEGETVY 160 G + +Y+V+ A PL L+G T Y V G T Sbjct: 141 LGTSTFSQYTVVDENAVAKIDAAS---PLEKVC-LIGCGFSTGYGSAVNVAKVTPGSTCA 196 Query: 161 VSAASGAVGQLVGQLAKMMG-CYVVGSAGSKEKVDLLKTKFGFDDAFN---YKEESDLTA 216 V G VG K G ++ +K+K K + G + N YK+ + Sbjct: 197 VFG-LGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAK-ELGATECINPQDYKKP--IQE 252 Query: 217 ALKRCFPNGIDIYFENVG--GKMLDAVLVNMNMHGRIAVCGMISQYNLENQEGVHNLSNI 274 LK G+D FE +G M+ ++L G + G+ + + L+ Sbjct: 253 VLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQNLSINPMLLLTGR 312 Query: 275 IYKRIRIQGFVVSDFYDKYSKFLEFVLPHI--REGKITYVEDVADGLEKAPEALVGLFHG 332 +K GF K + + ++ ++ + + EK E L G Sbjct: 313 TWKGAVYGGF-------KSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLHSG 365 Query: 333 KNVGKQVVV 341 K++ + V+ Sbjct: 366 KSI-RTVLT 373 >1U3W-A nrPDB Length = 374 Score = 70.6 bits (171), Expect = 1e-12, Method: Composition-based stats. Identities = 49/246 (19%), Positives = 86/246 (34%), Gaps = 20/246 (8%) Query: 102 GIVAWEEYSVITPMTHAHFKIQHTDVPLSYYTGLLGMPGMTAYAGFYEVCSPKEGETVYV 161 G+ + +Y+V+ A PL L+G T Y +V G T V Sbjct: 142 GVSTFSQYTVVDENAVAKIDAAS---PLEKVC-LIGCGFSTGYGSAVKVAKVTPGSTCAV 197 Query: 162 SAASGAVGQLVGQLAKMMG-CYVVGSAGSKEKVDLLKTKFGFDDAFN---YKEESDLTAA 217 G VG V K G ++ +K+K K + G + N YK+ + Sbjct: 198 FG-LGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAK-ELGATECINPQDYKKP--IQEV 253 Query: 218 LKRCFPNGIDIYFENVG--GKMLDAVLVNMNMHGRIAVCGMISQYNLENQEGVHNLSNII 275 LK G+D FE +G M+ ++L G + G+ + + + ++ Sbjct: 254 LKEMTDGGVDFSFEVIGQLDTMMASLLCCHEACGTSVIVGVP-----PDSQNLSINPMLL 308 Query: 276 YKRIRIQGFVVSDFYDKYSKFLEFVLPHIREGKITYVEDVADGLEKAPEALVGLFHGKNV 335 +G + F K S ++ + + EK E L GK++ Sbjct: 309 LTGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNVLPFEKINEGFDLLRSGKSI 368 Query: 336 GKQVVV 341 + V+ Sbjct: 369 -RTVLT 373 >5KIA-A nrPDB Length = 351 Score = 69.9 bits (169), Expect = 2e-12, Method: Composition-based stats. Identities = 42/238 (17%), Positives = 86/238 (36%), Gaps = 19/238 (7%) Query: 104 VAWEEYSVITPMTHAHFKIQHTDVPLSYYTGLLGMPGMTAYAGFYEVCSPKEGETVYVSA 163 A+ EY I + +D + + G TA + GE V ++ Sbjct: 127 GAFAEYLAIPAFNAFKIPPEISDDLAAIFDPF-GNATHTAL-----SFNL-VGEDVLITG 179 Query: 164 ASGAVGQLVGQLAKMMGCYVVGSAGSKEKVDLLKTKFGFDDAFNYKEESDLTAALKRCFP 223 A G +G + +AK +G V + L + G A N ES Sbjct: 180 A-GPIGVMAVAIAKHVGARNVVITDINDYRLDLARRMGATRAVNVSRESLRDVMADLHMT 238 Query: 224 NGIDIYFENVGGKM-LDAVLVNMNMHGRIAVCGMISQYNLENQEGVHNLSNIIYKRIRIQ 282 G D+ E G ++L +MN G++A+ G + + + + +I+K + I+ Sbjct: 239 EGFDVGLEMSGVPSAFTSLLESMNHGGKVALLG------IPPAQTAIDWNQVIFKGLEIK 292 Query: 283 GFVVSDFYDKYSKFLEFVLPHIREGKITYVEDVADGLEKAPEALVGLFHGKNVGKQVV 340 G + + + + V ++ + ++ + + G++ GK ++ Sbjct: 293 GIYGREM---FETWYKMVAMLQSGLDLSPIITHRFAVDDYEKGFAAMLSGES-GKVIL 346 >2OUI-A nrPDB Length = 360 Score = 69.5 bits (168), Expect = 2e-12, Method: Composition-based stats. Identities = 51/284 (17%), Positives = 95/284 (33%), Gaps = 45/284 (15%) Query: 83 VSRIIESGH--PDYKKGDLL--------WG---------------IVAWEEYSVITPMTH 117 V +I++ G K GD + WG + W+ + + Sbjct: 62 VGQIVKVGSLVKRLKVGDKVIVPAITPDWGEEESQRGYPMHSGGMLGGWKFSNFKDGVFS 121 Query: 118 AHFKIQHTDVPLSYYT-------GLLGMPGMTAYAGFYEVCSPKEGETVYVSAASGAVGQ 170 F + D L+ ++ +T E+ + K G+TV V G VG Sbjct: 122 EVFHVNEADANLALLPRDIKPEDAVMLSDMVTTGFHGAELANIKLGDTVCVIG-IGPVGL 180 Query: 171 LVGQLAKMMGCYVVGSAGSKEKVDLLKTKFGFDDAFNYKEESDLTAALKRCFPNGIDIYF 230 + A +G + + GS++ + ++G D NYK + LK G+D Sbjct: 181 MSVAGANHLGAGRIFAVGSRKHCCDIALEYGATDIINYKNGDIVEQILKATDGKGVDKVV 240 Query: 231 ENVGGK--MLDAVLVNMNMHGRIAVCGMISQYNLENQEGVHNLSNIIYKRIRIQGFVVSD 288 GG + + I + + +N + + I G + Sbjct: 241 -IAGGDVHTFAQAVKMIKPGSDIGNVNYLGEG--DNIPIPRSEWGVGMGHKHIHGGLTPG 297 Query: 289 FYDKYSKFLEFVLPHIREGKI---TYVEDVADGLEKAPEALVGL 329 + +E + I GK+ + +GLEK +AL+ + Sbjct: 298 GRVR----MEKLASLISTGKLDTSKLITHRFEGLEKVEDALMLM 337 >1UUF-A nrPDB Length = 369 Score = 69.1 bits (167), Expect = 3e-12, Method: Composition-based stats. Identities = 68/378 (17%), Positives = 117/378 (30%), Gaps = 67/378 (17%) Query: 2 TATNKQVILKDYVSGFPTESDFDFTTTTVELRVPEGTNSVLVKNLYLSCDPYMRIRMGKP 61 T+ K+ LK G + + R P G N V ++ Y + + Sbjct: 13 TSLYKKAGLKIKAVGAYSAKQ-PLEPMDITRREP-GPNDVKIEIAYCGV---CHSDLHQV 67 Query: 62 DPSTAALAQAYTPGQPIQGYGVSRIIESGHPDYKKGDLLW----------------GIVA 105 A PG I G V+ + Y GDL+ G+ Sbjct: 68 RSEWAGTVYPCVPGHEIVGRVVA--VGDQVEKYAPGDLVGVGCIVDSCKHCEECEDGLEN 125 Query: 106 WEEYSVITPMTHA---------------------HFKIQHTDVPLSYYTGLLGMPGMTAY 144 + ++ T + +I+H L+ LL G+T Y Sbjct: 126 YCDHMTGTYNSPTPDEPGHTLGGYSQQIVVHERYVLRIRHPQEQLAAVAPLL-CAGITTY 184 Query: 145 AGFYEVCSPKEG-ETVYVSAASGAVGQLVGQLAKMMGCYVVGSAGSKEKVDLLKTKFGFD 203 + + G G +G + +LA MG +VV S+ K + K G D Sbjct: 185 SPLR---HWQAGPGKKVGVVGIGGLGHMGIKLAHAMGAHVVAFTTSEAKREAAK-ALGAD 240 Query: 204 DAFNYKEESDLTAALKRCFPNGIDIYFENVGGK-MLDAVLVNMNMHGRIAVCGMISQYNL 262 + N + ++ A LK D V LD + G + + G + Sbjct: 241 EVVNSRNADEMAAHLKS-----FDFILNTVAAPHNLDDFTTLLKRDGTMTLVGAPAT--- 292 Query: 263 ENQEGVHNLSNIIYKRIRIQGFVVSDFYDKYSKFLEFVLPHIREGKITYVEDVADGLEKA 322 + N+I KR I G ++ + +L E I ++ ++ Sbjct: 293 --PHKSPEVFNLIMKRRAIAGSMIGG-----IPETQEMLDFCAEHGIVADIEMIRA-DQI 344 Query: 323 PEALVGLFHGKNVGKQVV 340 EA + G + V+ Sbjct: 345 NEAYERMLRGDVKYRFVI 362 >1CDO-A nrPDB Length = 374 Score = 66.4 bits (160), Expect = 2e-11, Method: Composition-based stats. Identities = 47/244 (19%), Positives = 82/244 (33%), Gaps = 17/244 (6%) Query: 96 KGDLLW---GIVAWEEYSVITPMTHAHFKIQHTDVPLSYYTGLLGMPGMTAYAGFYEVCS 152 KG + G + +Y+V+ + A PL LLG T + Sbjct: 134 KGRKVLQFLGTSTFSQYTVVNQIAVAKID---PSAPLDTVC-LLGCGVSTGFGAAVNTAK 189 Query: 153 PKEGETVYVSAASGAVGQLVGQLAKMMGC-YVVGSAGSKEKVDLLKTKFGFDDAFNYKEE 211 + G T V GAVG G ++ + +K + K D Sbjct: 190 VEPGSTCAVFG-LGAVGLAAVMGCHSAGAKRIIAVDLNPDKFEKAKVFGATDFVNPNDHS 248 Query: 212 SDLTAALKRCFPNGIDIYFENVG--GKMLDAVLVNMNMHGRIAVCGMISQYNLENQEGVH 269 ++ L + G+D E VG G M +A+ + G + G +++ + + Sbjct: 249 EPISQVLSKMTNGGVDFSLECVGNVGVMRNALESCLKGWGVSVLVGWTDLHDVATRP-IQ 307 Query: 270 NLSNIIYKRIRIQGFVVSDFYDKYSKFLEFVLPHIREGKITYVEDVADGLEKAPEALVGL 329 ++ +K GF D K K ++ K+ LE +A+ + Sbjct: 308 LIAGRTWKGSMFGGFKGKDGVPKMVKAYLD-----KKVKLDEFITHRMPLESVNDAIDLM 362 Query: 330 FHGK 333 HGK Sbjct: 363 KHGK 366 >1P0F-A nrPDB Length = 373 Score = 66.0 bits (159), Expect = 2e-11, Method: Composition-based stats. Identities = 46/247 (18%), Positives = 81/247 (32%), Gaps = 21/247 (8%) Query: 100 LWGIVAWEEYSVITPMTHAHFKIQHTDVPLSYYTGLLGMPGMTAYAGFYEVCSPKEGETV 159 L G + EY+V+ + A + + L+G T Y G T Sbjct: 141 LMGTSTFTEYTVVADIAVAKIDPKAP-----LESCLIGCGFATGYGAAVNTAKVTPGSTC 195 Query: 160 YVSAASGAVGQLVGQLAKMMGCYVVGSAGSKEKVDLLKTKFGFDDAFNYKE-ESDLTAAL 218 V G VG K G + G+ + + G + N K+ + + + Sbjct: 196 AVFG-LGGVGFSAIVGCKAAGASRIIGVGTHKDKFPKAIELGATECLNPKDYDKPIYEVI 254 Query: 219 KRCFPNGIDIYFENVG--GKMLDAVLVNMNMHGRIAVCGMISQYNLENQEGVHNLSNIIY 276 G+D E G M++A+ G V G+ S + + L+ Sbjct: 255 CEKTNGGVDYAVECAGRIETMMNALQSTYCGSGVTVVLGLASPNERLPLDPLLLLTGRSL 314 Query: 277 KRIRIQGF---VVSDFYDKYSKFLEFVLPHIREGKITYVEDVADGLEKAPEALVGLFHGK 333 K GF VS D Y K ++ + ++ L++ +A L G+ Sbjct: 315 KGSVFGGFKGEEVSRLVDDYMK---------KKINVNFLVSTKLTLDQINKAFELLSSGQ 365 Query: 334 NVGKQVV 340 V ++ Sbjct: 366 GVRSIMI 372 >1YKF-A nrPDB Length = 352 Score = 66.0 bits (159), Expect = 2e-11, Method: Composition-based stats. Identities = 52/295 (17%), Positives = 101/295 (34%), Gaps = 38/295 (12%) Query: 83 VSRIIESGH--PDYKKGDLLWG-----------------------IVAWEEYSVITPMTH 117 V ++E G D+K GD + + W+ +V + Sbjct: 62 VGEVVEVGSEVKDFKPGDRVVVPAITPDWRTSEVQRGYHQHSGGMLAGWKFSNVKDGVFG 121 Query: 118 AHFKIQHTDVPLSYYTGLLGMPG-------MTAYAGFYEVCSPKEGETVYVSAASGAVGQ 170 F + D+ L++ + + MT E+ + G TV V G VG Sbjct: 122 EFFHVNDADMNLAHLPKEIPLEAAVMIPDMMTTGFHGAELADIELGATVAVLG-IGPVGL 180 Query: 171 LVGQLAKMMGCYVVGSAGSKEKVDLLKTKFGFDDAFNYKEESDLTAALKRCFPNGIDIYF 230 + AK+ G + + GS+ +G D NYK+ + + G+D Sbjct: 181 MAVAGAKLRGAGRIIAVGSRPVCVDAAKYYGATDIVNYKDGPIESQIMNLTEGKGVDAAI 240 Query: 231 ENVGG-KMLDAVLVNMNMHGRIAVCGMISQYNLENQEGVHNLSNIIYKRIRIQGFVVSDF 289 G ++ + + G IA + + + + +K I+G + Sbjct: 241 IAGGNADIMATAVKIVKPGGTIANVNYFGEGEVLPVPRLEWGCGMAHK--TIKGGLCPG- 297 Query: 290 YDKYSKFLEFVLPHIREGKITYVEDVADGLEKAPEALVGL-FHGKNVGKQVVVVA 343 + L ++ + R V V G + +A + + K++ K VV++A Sbjct: 298 GRLRMERLIDLVFYKRVDPSKLVTHVFRGFDNIEKAFMLMKDKPKDLIKPVVILA 352 >2H6E-A nrPDB Length = 344 Score = 65.2 bits (157), Expect = 4e-11, Method: Composition-based stats. Identities = 55/297 (18%), Positives = 85/297 (28%), Gaps = 61/297 (20%) Query: 84 SRIIESGH-PDYKKGDLLWGIVAWEEYSVITPMTHAHFKI--------QHTDVPLSYY-- 132 I+E G KKGD + W + F I Q T+ S Y Sbjct: 69 GTIVEVGELAKVKKGDNVVVYATWGD-LTCRYCREGKFNICKNQIIPGQTTNGGFSEYML 127 Query: 133 -----------------TGLLGMPGMTAYAGFYEVCSP--KEGETVYVSAASGAVGQLVG 173 L G T+ + K E V + G + Sbjct: 128 VKSSRWLVKLNSLSPVEAAPLADAGTTSMGAIRQALPFISKFAEPVVIVNGIGGLAVYTI 187 Query: 174 QLAKMM-GCYVVGSAGSKEKVDLLKTKFGFDDAFNYKEESDLTAALKRCFPNGIDIYFEN 232 Q+ K + + +K + G D K+ L K G I + Sbjct: 188 QILKALMKNITIVGISRSKKHRDFALELGADYVSEMKDAESLIN--KLTDGLGASIAIDL 245 Query: 233 VGGKMLDAVL-VNMNMHGRIAVCGMISQYNLENQEGVHNLSNIIYKRIRIQGFVVSDFYD 291 VG + L + G I + GM KR+ ++ F + + Sbjct: 246 VGTEETTYNLGKLLAQEGAIILVGMEG------------------KRVSLEAFDTAVWNK 287 Query: 292 KYSKF-------LEFVLPHIREGKITYVEDVADGLEKAPEALVGLFHGKNVGKQVVV 341 K LE V+ GKI + L+ +A L G+ G+QV+ Sbjct: 288 KLLGSNYGSLNDLEDVVRLSESGKIKPYI-IKVPLDDINKAFTNLDEGRVDGRQVIT 343 >4DLA-A nrPDB Length = 396 Score = 64.9 bits (156), Expect = 5e-11, Method: Composition-based stats. Identities = 49/269 (18%), Positives = 89/269 (33%), Gaps = 23/269 (8%) Query: 75 GQPIQGYGVSRIIESGHPDYKKGDL----LWGIVAWEEYSVITPMTHAHFKIQHTDVPLS 130 G+ GV ++ + G + +Y+V+ ++ A PL Sbjct: 131 GKVRAATGVGVMMNDRKSRFSINGKPIYHFMGTSTFSQYTVVHDVSVAKID---PVAPLE 187 Query: 131 YYTGLLGMPGMTAYAGFYEVCSPKEGETVYVSAASGAVGQLVGQLAKMMGC-YVVGSAGS 189 LLG T + + G V V G VG V + AK G ++G Sbjct: 188 KVC-LLGCGVPTGLGAVWNTAKVEPGSIVAVFG-LGTVGLAVAEGAKAAGASRIIGIDID 245 Query: 190 KEKVDLLKTKFGFDDAFNYKE-ESDLTAALKRCFPNGIDIYFENVGGKMLDAV-LVNMNM 247 +K D K FG + N KE E + + G+D FE +G + L + Sbjct: 246 SKKFDRAKN-FGVTEFINPKEHEQPIQQVIVDLTDGGVDYSFECIGNVSVMRSALECCHK 304 Query: 248 H-GRIAVCGMISQYNLENQEGVHNLSNIIYKRIRIQGFVVSDFYDKYSKFLEFVLPHIRE 306 G + G+ + + ++ ++K GF K + ++ + Sbjct: 305 GWGTSVIVGVAASGQEISTRPFQLVTGRVWKGTAFGGF-------KSRSQVPSLVDKYLK 357 Query: 307 GKITYVEDVADGLE--KAPEALVGLFHGK 333 +I E + + +A + G Sbjct: 358 KEIKVDEYITHNMTLADINKAFDLMHDGD 386 >1Q1N-A nrPDB Length = 360 Score = 64.5 bits (155), Expect = 6e-11, Method: Composition-based stats. Identities = 46/255 (18%), Positives = 80/255 (31%), Gaps = 28/255 (10%) Query: 83 VSRIIESGHPDYKKGDLLWGIVAWEEYSVITPMTHAHFKIQHTDVPLSYYTGLLGMPGMT 142 ++ + + Y+ G + Y + H HF + + S+ L G+T Sbjct: 114 CTKFVTTYSQPYEDG--YVSQGGYANYVRV----HEHFVVPIPENIPSHLAAPLLCGGLT 167 Query: 143 AYAGFYEVCSPKEGETVYVSAASGAVGQLVGQLAKMMGCYVVGSAGSKEKVDLLKTKFGF 202 Y+ G+ V + G + ++K MG + S K + K G Sbjct: 168 VYSPLVRNGC-GPGKKVGIVGLGGIG-SMGTLISKAMGAETYVISRSSRKRE-DAMKMGA 224 Query: 203 DDAFNYKEESDLTAALKRCFPNGIDIYFENVGGKM---LDAVLVNMNMHGRIAVCGMISQ 259 D EE D F D+ + + M + GRI Sbjct: 225 DHYIATLEEGDWGEKYFDTF----DLIVVCASSLTDIDFNIMPKAMKVGGRIVSI----- 275 Query: 260 YNLENQEGVHNLSNIIYKRIRIQGFVVSDFYDKYSKFLEFVLPHIREGKIT-YVEDVADG 318 ++ Q + +L K + I + K L +L + E I +VE + G Sbjct: 276 -SIPEQHEMLSLKPYGLKAVSISYSALGS-----IKELNQLLKLVSEKDIKIWVETLPVG 329 Query: 319 LEKAPEALVGLFHGK 333 EA + G Sbjct: 330 EAGVHEAFERMEKGD 344 >5YLN-A nrPDB Length = 356 Score = 64.5 bits (155), Expect = 6e-11, Method: Composition-based stats. Identities = 48/302 (15%), Positives = 94/302 (31%), Gaps = 49/302 (16%) Query: 79 QGYGVSRIIESGHPDYKKGDLLWGI----------------------VAWEEYSVITPMT 116 +G G+ + G ++KKGD + W +I M Sbjct: 65 EGIGIVEEVGEGVSNFKKGDKVLISCVCACGKCYYCKKGIYAHCEDEGGWIFGHLIDGMQ 124 Query: 117 HAHFKIQHTDVPLSYY------TGLLGMPGM--TAYAGFYEVCSPKEGETVYVSAASGAV 168 + ++ H D L + L+ + + T Y + G +V + SG V Sbjct: 125 AEYLRVPHADNTLYHTPEDLSDEALVMLSDILPTGYEIGVLKGKVEPGCSVAIIG-SGPV 183 Query: 169 GQLVGQLAKMM-GCYVVGSAGSKEKVDLLKTKFGFDDAFNYKE-ESDLTAALKRCFPNGI 226 G A+ ++ +++ FG N + E + G+ Sbjct: 184 GLAALLTAQFYSPAKLIMVDLDDNRLE-TALSFGATHKVNSSDPEKAIKEIYDLTDGRGV 242 Query: 227 DIYFENVGG-KMLDAVLVNMNMHGRIAVCGMISQYNLENQEGVHNLSNIIYKRIRIQGFV 285 D+ E VG D + + G +A CG + + +L + + I + + Sbjct: 243 DVAIEAVGIPATFDFCQKIIGVDGTVANCG------VHGKPVEFDLDKLWIRNINVTTGL 296 Query: 286 VSDFYDKYSKFLEFVLPHIREGKITYVEDVAD--GLEKAPEALVGLFHGKNVGKQVVVVA 343 VS +L + KI + V L + +A + V++ Sbjct: 297 VSTNTTP------QLLKALESHKIEPEKLVTHYFKLSEIEKAYEVFSKAADHHAIKVIIE 350 Query: 344 RE 345 + Sbjct: 351 ND 352 >1F8F-A nrPDB Length = 371 Score = 64.1 bits (154), Expect = 7e-11, Method: Composition-based stats. Identities = 45/237 (18%), Positives = 88/237 (37%), Gaps = 14/237 (5%) Query: 98 DLLWGIVAWEEYSVITPMTHAHFKIQHTDVPLSYYTGLLGMPGMTAYAGFYEVCSPKEGE 157 D + ++ Y++ DVP+ G LG T Sbjct: 137 DHFFAQSSFATYALSRENNTVKVT---KDVPI-ELLGPLGCGIQTGAGACINALKVTPAS 192 Query: 158 TVYVSAASGAVGQLVGQLAKMMGCYVVGSAGSKEKVDLLKTKFGFDDAFNYKEESDLTAA 217 + V+ +GAVG AK+ G ++ + E L + G N K + + AA Sbjct: 193 SF-VTWGAGAVGLSALLAAKVCGASIIIAVDIVESRLELAKQLGATHVINSKTQDPV-AA 250 Query: 218 LKRCFPNGIDIYFENVGG-KMLDAVLVNMNMHGRIAVCGMISQYNLENQEGVHNLSNIIY 276 +K G++ E+ G ++L + + + G+IAV G ++++++ Sbjct: 251 IKEITDGGVNFALESTGSPEILKQGVDALGILGKIAVVGAPQL----GTTAQFDVNDLLL 306 Query: 277 KRIRIQGFVVSDFYDKYSKFLEFVLPHIREGKITYVEDVA-DGLEKAPEALVGLFHG 332 I G V K KF+ ++ ++GK + + V ++ +A + G Sbjct: 307 GGKTILGVVEGSGSPK--KFIPELVRLYQQGKFPFDQLVKFYAFDEINQAAIDSRKG 361 >1EE2-A nrPDB Length = 373 Score = 64.1 bits (154), Expect = 8e-11, Method: Composition-based stats. Identities = 50/241 (20%), Positives = 81/241 (33%), Gaps = 19/241 (7%) Query: 101 WGIVAWEEYSVITPMTHAHFKIQHTDVPLSYYTGLLGMPGMTAYAGFYEVCSPKEGETVY 160 G + +Y+V+ ++ A L+G T Y +V +G T Sbjct: 140 LGTSTFSQYTVVDEISVAKIDAASPL----EKVCLVGCGFSTGYGSAVKVAKVTQGSTCA 195 Query: 161 VSAASGAVGQLVGQLAKMMG-CYVVGSAGSKEKVDLLKTKFGFDDAFN---YKEESDLTA 216 V G VG V K G ++G +K+K K + G + N YK+ + Sbjct: 196 VFG-LGGVGLSVIMGCKAAGAARIIGVDINKDKFAKAK-EVGATECVNPQDYKKP--IQE 251 Query: 217 ALKRCFPNGIDIYFENVGG-KMLDAVLVNMNMH-GRIAVCGMISQYNLENQEGVHNLSNI 274 L G+D FE +G + A L G + G+ + + LS Sbjct: 252 VLTEMSNGGVDFSFEVIGRLDTMVAALSCCQEAYGVSVIVGVPPDSQNLSMNPMLLLSGR 311 Query: 275 IYKRIRIQGFVVSDFYDKYSKFLEFVLPHIREGKITYVEDVADGLEKAPEALVGLFHGKN 334 +K GF D K +F+ + + EK E L GK+ Sbjct: 312 TWKGAIFGGFKSKDSVPKLVA--DFMAKKFA---LDPLITHVLPFEKINEGFDLLRSGKS 366 Query: 335 V 335 + Sbjct: 367 I 367 >4RQU-A nrPDB Length = 375 Score = 64.1 bits (154), Expect = 8e-11, Method: Composition-based stats. Identities = 41/246 (16%), Positives = 92/246 (37%), Gaps = 16/246 (6%) Query: 101 WGIVAWEEYSVITPMTHAHFKIQHTDVPLSYYTGLLGMPGMTAYAGFYEVCSPKEGETVY 160 G + EY+V+ A D PL ++ T V PK+G++V Sbjct: 140 LGTSTFSEYTVVHSGQVAKIN---PDAPLDKVC-IVSCGLSTGLGATLNVAKPKKGQSVA 195 Query: 161 VSAASGAVGQLVGQLAKMMGC-YVVGSAGSKEKVDLLKTKFGFDDAFNYKEESD-LTAAL 218 + GAVG + A++ G ++G + ++ D K +FG + N K+ + + Sbjct: 196 IFG-LGAVGLGAAEGARIAGASRIIGVDFNSKRFDQAK-EFGVTECVNPKDHDKPIQQVI 253 Query: 219 KRCFPNGIDIYFENVGG-KMLDAVLVNMNMH-GRIAVCGMISQYNLENQEGVHNLSNIIY 276 G+D E G + + ++ G + G+ S+ + + N + Sbjct: 254 AEMTDGGVDRSVECTGSVQAMIQAFECVHDGWGVAVLVGVPSKDDAFKT----HPMNFLN 309 Query: 277 KRIRIQGFVVSDFYDKYSKFLEFVLPHIREGKITYVEDVADGLEKAPEALVGLFHGKNVG 336 +R ++G ++ K +E ++ + +A + G+++ Sbjct: 310 ER-TLKGTFFGNYKPKTDIPGVVEKYMNKELELEKFITHTVPFSEINKAFDYMLKGESI- 367 Query: 337 KQVVVV 342 + ++ + Sbjct: 368 RCIITM 373 >3FPL-A nrPDB Length = 351 Score = 64.1 bits (154), Expect = 1e-10, Method: Composition-based stats. Identities = 52/294 (17%), Positives = 101/294 (34%), Gaps = 38/294 (12%) Query: 83 VSRIIESGH--PDYKKGDLLWG-----------------------IVAWEEYSVITPMTH 117 V ++E G D+K GD + + W+ + + Sbjct: 62 VGEVVEVGSEVKDFKPGDRVIVPCTTPDWRSLEVQAGFQQHSNGMLAGWKFSNFKDGVFG 121 Query: 118 AHFKIQHTDVPLSYYTGLLGMPG-------MTAYAGFYEVCSPKEGETVYVSAASGAVGQ 170 +F + D+ L+ + + MT E+ + G TV V G VG Sbjct: 122 EYFHVNDADMNLAILPKDMPLENAVMITDMMTTGFHGAELADIELGATVAVLG-IGPVGL 180 Query: 171 LVGQLAKMMGCYVVGSAGSKEKVDLLKTKFGFDDAFNYKEESDLTAALKRCFPNGIDIYF 230 + AK+ G + + GS+ +G D NYK+ + + G+D Sbjct: 181 MAVAGAKLRGAGRIIAVGSRPVCVDAAKYYGATDIVNYKDGPIESQIMNLTEGKGVDAAI 240 Query: 231 ENVGG-KMLDAVLVNMNMHGRIAVCGMISQYNLENQEGVHNLSNIIYKRIRIQGFVVSDF 289 G ++ + + G IA + + + + +K I+G + Sbjct: 241 IAGGNADIMATAVKIVKPGGTIANVNYFGEGEVLPVPRLEWGCGMAHK--TIKGGLCPG- 297 Query: 290 YDKYSKFLEFVLPHIREGKITYVEDVADGLEKAPEALVGL-FHGKNVGKQVVVV 342 ++ L ++ + R V V G + EAL+ + K++ K VV++ Sbjct: 298 GRLRAEMLRDMVVYNRVDLSKLVTHVYHGFDHIEEALLLMKDKPKDLIKAVVIL 351 >4JJI-A nrPDB Length = 378 Score = 63.3 bits (152), Expect = 1e-10, Method: Composition-based stats. Identities = 49/259 (18%), Positives = 94/259 (36%), Gaps = 22/259 (8%) Query: 75 GQPIQGYGVSRIIESGHPDYKKGDL----LWGIVAWEEYSVITPMTHAHFKIQHTDVPLS 130 G+ GV ++ + G + +Y+V+ ++ A PL Sbjct: 113 GKVRSATGVGIMMNDRKSRFSVNGKPIYHFMGTSTFSQYTVVHDVSVAKID---PTAPLD 169 Query: 131 YYTGLLGMPGMTAYAGFYEVCSPKEGETVYVSAASGAVGQLVGQLAKMMGC-YVVGSAGS 189 LLG T + + G V + G VG V + AK G ++G Sbjct: 170 KVC-LLGCGVPTGLGAVWNTAKVEPGSNVAIFG-LGTVGLAVAEGAKTAGASRIIGIDID 227 Query: 190 KEKVDLLKTKFGFDDAFNYKEESD-LTAALKRCFPNGIDIYFENVGG-KMLDAVLVNMNM 247 +K + K KFG ++ N K+ + + G+D FE +G ++ A L + Sbjct: 228 SKKYETAK-KFGVNEFVNPKDHDKPIQEVIVDLTDGGVDYSFECIGNVSVMRAALECCHK 286 Query: 248 H-GRIAVCGMISQYNLENQEGVHNLSNIIYKRIRIQGF--------VVSDFYDKYSKFLE 298 G + G+ + + ++ ++K GF +V + +K K E Sbjct: 287 GWGTSVIVGVAASGQEISTRPFQLVTGRVWKGTAFGGFKSRTQVPWLVEKYMNKEIKVDE 346 Query: 299 FVLPHIREGKITYVEDVAD 317 ++ ++ G+I D+ Sbjct: 347 YITHNLTLGEINKAFDLLH 365 >1MC5-A nrPDB Length = 374 Score = 63.3 bits (152), Expect = 1e-10, Method: Composition-based stats. Identities = 46/243 (18%), Positives = 80/243 (32%), Gaps = 15/243 (6%) Query: 101 WGIVAWEEYSVITPMTHAHFKIQHTDVPLSYYTGLLGMPGMTAYAGFYEVCSPKEGETVY 160 G + EY+V+ ++ A PL LLG T Y + G Sbjct: 141 MGTSTFSEYTVVADISVAKID---PLAPLDKVC-LLGCGISTGYGAAVNTAKLEPGSVCA 196 Query: 161 VSAASGAVGQLVGQLAKMMGC-YVVGSAGSKEKVDLLKTKFGFDDAFNYKEESD-LTAAL 218 V G VG V K+ G ++G +K+K K +FG + N ++ S + L Sbjct: 197 VFG-LGGVGLAVIMGCKVAGASRIIGVDINKDKFARAK-EFGATECINPQDFSKPIQEVL 254 Query: 219 KRCFPNGIDIYFENVGGKMLDAVLVNMNMHGRIAVCGMISQYNLENQEGVHNLSNIIYKR 278 G+D FE +G V+ + + E + + Sbjct: 255 IEMTDGGVDYSFECIGNV---KVMRAALEACHKGWGVSVVVGVAASGEEIATRPFQLVTG 311 Query: 279 IRIQGFVVSDFYDKYSKFLEFVLPHIREGKITYVEDVADGLE--KAPEALVGLFHGKNVG 336 +G + + + ++ KI E V L + +A + GK++ Sbjct: 312 RTWKGTAFGGWKSV--ESVPKLVSEYMSKKIKVDEFVTHNLSFDEINKAFELMHSGKSIR 369 Query: 337 KQV 339 V Sbjct: 370 TVV 372 >6FG0-A nrPDB Length = 352 Score = 62.9 bits (151), Expect = 2e-10, Method: Composition-based stats. Identities = 48/241 (19%), Positives = 87/241 (36%), Gaps = 22/241 (9%) Query: 104 VAWEEYSVITPMTHAHFKIQHTDVPLSYYTGLLGMPGMTAYAGFYEVCSP-KEGETVYVS 162 + EY ++ H I D L G+T Y V G T V Sbjct: 123 GSMAEYMIVDSARH-LVPIGDLDPV---AAAPLTDAGLTPYHAISRVLPLLGPGSTAVVI 178 Query: 163 AASGAVGQLVGQLAKMM-GCYVVGSAGSKEKVDLLKTKFGFDDAFNYKEESDLTAALKRC 221 G +G + Q+ + + V+ +++ L + + G D A A + Sbjct: 179 GV-GGLGHVGIQILRAVSAARVIAVDLDDDRLALAR-EVGADAAVK-SGAGAADAIRELT 235 Query: 222 FPNGIDIYFENVGGK-MLDAVLVNMNMHGRIAVCGMISQYNLENQEGVHNLSNIIYKRIR 280 G F+ VG + +D + + G I+V G+ + + + + I Sbjct: 236 GGQGATAVFDFVGAQSTIDTAQQVVAVDGHISVVGIHAG----------AHAKVGFWMIP 285 Query: 281 IQGFVVSDFYDKYSKFLEFVLPHIREGKITYVEDVADGLEKAPEALVGLFHGKNVGKQVV 340 VV+ ++ S+ +E V+ R G++ + L++ P A L G G+ VV Sbjct: 286 FGASVVTPYWGTRSELME-VVALARAGRLDIHTE-TFTLDEGPAAYRRLREGSIRGRGVV 343 Query: 341 V 341 V Sbjct: 344 V 344 >1D1T-A nrPDB Length = 373 Score = 62.5 bits (150), Expect = 3e-10, Method: Composition-based stats. Identities = 52/274 (18%), Positives = 92/274 (33%), Gaps = 23/274 (8%) Query: 76 QPIQGYGVSRIIESGHPDYK-KGDLL---WGIVAWEEYSVITPMTHAHFKIQHTDVPLSY 131 I G GV + G + KG + + EY+V+ + A D Sbjct: 114 SDITGRGV---LADGTTRFTCKGKPVHHFLNTSTFTEYTVVDESSVAKID----DAAPPE 166 Query: 132 YTGLLGMPGMTAYAGFYEVCSPKEGETVYVSAASGAVGQLVGQLAKMMGC-YVVGSAGSK 190 L+G T Y + K G T V G VG V K G ++G +K Sbjct: 167 KVCLIGCGFSTGYGAAVKTGKVKPGSTCVVFG-LGGVGLSVIMGCKSAGASRIIGIDLNK 225 Query: 191 EKVDLLKTKFGFDDAFNYKEE-SDLTAALKRCFPNGIDIYFENVG--GKMLDAVLVNMNM 247 +K + G + + K+ ++ L N + FE +G M+DA+ Sbjct: 226 DKFEKA-MAVGATECISPKDSTKPISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMN 284 Query: 248 HGRIAVCGMISQYNLENQEGVHNLSNIIYKRIRIQGFVVSDFYDKYSKFLEFVLPHIREG 307 +G V G+ + + + + +K G + D EF+ Sbjct: 285 YGTSVVVGVPPSAKMLTYDPMLLFTGRTWKGCVFGG--LKSRDDVPKLVTEFLAKKF--- 339 Query: 308 KITYVEDVADGLEKAPEALVGLFHGKNVGKQVVV 341 + + +K E L G+++ + V+ Sbjct: 340 DLDQLITHVLPFKKISEGFELLNSGQSI-RTVLT 372 >3IP1-A nrPDB Length = 404 Score = 60.2 bits (144), Expect = 1e-09, Method: Composition-based stats. Identities = 38/215 (17%), Positives = 72/215 (33%), Gaps = 11/215 (5%) Query: 131 YYTGLLGMPGMTAYAG-FYEVCSPKEGETVYVSAASGAVGQLVGQLAKMMGCYVVGSAGS 189 + G L P AY + G+ V + G +G + K G V + Sbjct: 188 FLAGSLVEPTSVAYNAVIVRGGGIRPGDNVVILGG-GPIGLAAVAILKHAGASKVILSEP 246 Query: 190 KEKVDLLKTKFGFDDAFNYKEESDLTAALKRCFPNGIDIYFENVGGKML---DAVLVNMN 246 E L + G D + +E+ + A L G ++ E G L V Sbjct: 247 SEVRRNLAKELGADHVIDPTKENFVEAVLDYTNGLGAKLFLEATGVPQLVWPQIEEVIWR 306 Query: 247 MHGRIAVCGMISQYNLENQEGVHNLSNIIYKRIRIQGFVVSDFYDKYSKFLEFVLPHIRE 306 G A ++++ + + +R +I G S + + F + Sbjct: 307 ARGINATVAIVARADAKIPLTGEVFQ---VRRAQIVG---SQGHSGHGTFPRVISLMASG 360 Query: 307 GKITYVEDVADGLEKAPEALVGLFHGKNVGKQVVV 341 +T + +E+ PE + L K++ K ++ Sbjct: 361 MDMTKIISKTVSMEEIPEYIKRLQTDKSLVKVTML 395 >4UEJ-A nrPDB Length = 346 Score = 60.2 bits (144), Expect = 1e-09, Method: Composition-based stats. Identities = 44/242 (18%), Positives = 83/242 (34%), Gaps = 15/242 (6%) Query: 104 VAWEEYSVITPMTHAHFKIQHTDVPLSYYTGLLGMPGMTAYAGFYEVCSPKEGETVYVSA 163 + EY V+ TD+P+ + +T + + E + V + Sbjct: 115 GGFAEYIVVKRKNVFAL---PTDMPIEDGA---FIEPITVGLHAFHLAQGCENKNVIIIG 168 Query: 164 ASGAVGQLVGQLAKMMGCY-VVGSAGSKEKVDLLKTKFGFDDAFNYKEESDLTAALKRCF 222 A G +G L Q A +G V S EK+ L K+ FG FN E S Sbjct: 169 A-GTIGLLAIQCAVALGAKSVTAIDISSEKLALAKS-FGAMQTFNSSEMSAPQMQSVLRE 226 Query: 223 PNGIDIYFENVG-GKMLDAVLVNMNMHGRIAVCGMISQYNLENQEGVHNLSNIIYKRIRI 281 + E G + ++ + H ++A+ G + Q + I+ K + + Sbjct: 227 LRFNQLILETAGVPQTVELAVEIAGPHAQLALVGTLHQ---DLHLTSATFGKILRKELTV 283 Query: 282 QGFVVSDFYDKYSKFLEFVLPHIREGK--ITYVEDVADGLEKAPEALVGLFHGKNVGKQV 339 G ++ + E + E K + + E +A+ + GK + Sbjct: 284 IGSWMNYSSPWPGQEWETASRLLTERKLSLEPLIAHRGSFESFAQAVRDIARNAMPGKVL 343 Query: 340 VV 341 ++ Sbjct: 344 LI 345 >5FI5-A nrPDB Length = 357 Score = 58.7 bits (140), Expect = 3e-09, Method: Composition-based stats. Identities = 53/295 (17%), Positives = 94/295 (31%), Gaps = 47/295 (15%) Query: 37 GTNSVLVKNLYLSCDPYMRIRMGKPDPSTAALAQAYTPGQPIQGYGVSRIIESGHPDYKK 96 G + V +K LY Y R M K + Y G I G V+ + S +K Sbjct: 41 GEHDVQLKVLYCGTCQYDR-EMSKNKFG--FTSYPYVLGHEIVG-EVTE-VGSKVQKFKV 95 Query: 97 GDLLWGIVAWEEYSVITPMTHAH--------------------------FKIQHTD-VPL 129 GD + E T+ F I+ + +PL Sbjct: 96 GDKVGVASIIETCGKCEMCTNEVENYCPEAGSIDSNYGACSNIAVINENFVIRWPENLPL 155 Query: 130 SYYTGLLGMPGMTAYAGFYEVCSPKEGETVYVSAASGAVGQLVGQLAKMMGCYVVGSAGS 189 LL G+TAY+ K G+ + ++ G + + AK G V + S Sbjct: 156 DSGVPLL-CAGITAYSPMKRYGLDKPGKRIGIAGLGGLG-HVALRFAKAFGAKVTVISSS 213 Query: 190 KEKVDLLKTKFGFDDAFNYKEESDLTAALKRCFPNGIDIYFENV-GGKMLDAVLVNMNMH 248 +K KFG D ++ A +D + + G L+ +L + Sbjct: 214 LKKKREAFEKFGADSFLVSSNPEEMQGA-----AGTLDGIIDTIPGNHSLEPLLALLKPL 268 Query: 249 GRIAVCGMISQYNLENQEGVHNLSNIIYKRIRIQGFVVSDFYDKYSKFLEFVLPH 303 G++ + G + + + ++ + + + +EF H Sbjct: 269 GKLIILGA-------PEMPFEVPAPSLLMGGKVMAASTAGSMKEIQEMIEFAAEH 316 >1E3E-A nrPDB Length = 376 Score = 56.0 bits (133), Expect = 3e-08, Method: Composition-based stats. Identities = 40/239 (16%), Positives = 77/239 (32%), Gaps = 17/239 (7%) Query: 101 WGIVAWEEYSVITPMTHAHFKIQHTDVPLSYYTGLLGMPGMTAYAGFYEVCSPKEGETVY 160 G+ ++ +Y+V++ A D L+G + Y G T Sbjct: 145 MGVSSFSQYTVVSEANLARVD----DEANLERVCLIGCGFSSGYGAAINTAKVTPGSTCA 200 Query: 161 VSAASGAVGQLVGQLAKMMGC-YVVGSAGSKEKVDLLKTKFGFDDAFNYKEESD-LTAAL 218 V G VG K+ G ++ + EK K G D N +E + + Sbjct: 201 VFG-LGCVGLSAIIGCKIAGASRIIAIDINGEKFPKAK-ALGATDCLNPRELDKPVQDVI 258 Query: 219 KRCFPNGIDIYFENVG-GKMLDAVLVNMNMH-GRIAVCGMISQYNLENQEGVHNLSNIIY 276 G+D + G + L A + + G V G ++ + + I+ Sbjct: 259 TELTAGGVDYSLDCAGTAQTLKAAVDCTVLGWGSCTVVGA-----KVDEMTIPTVDVILG 313 Query: 277 KRIRIQGFVVSDFYDKYSKFLEFVLPHIREGKITYVEDVADGLEKAPEALVGLFHGKNV 335 + I G + S ++ + + A E +A+ + GK++ Sbjct: 314 R--SINGTFFGGWKSVDSVPNLVSDYKNKKFDLDLLVTHALPFESINDAIDLMKEGKSI 370 >2CF5-A nrPDB Length = 357 Score = 55.2 bits (131), Expect = 4e-08, Method: Composition-based stats. Identities = 39/240 (16%), Positives = 83/240 (34%), Gaps = 23/240 (9%) Query: 102 GIVAWEEYSVITPMTHAHFKIQHTDVPLSYYTGLLGMPGMTAYAGFYEVCSPKEGETVYV 161 + + +V+ H F ++ + L G+T Y+ K+ Sbjct: 131 TQGGFAKATVV----HQKFVVKIPEGMAVEQAAPLLCAGVTVYSPLSHFG-LKQPGLRGG 185 Query: 162 SAASGAVGQLVGQLAKMMGCYVVGSAGSKEKVDLLKTKFGFDDAFNYKEESDLTAALKRC 221 G VG + ++AK MG +V + S +K + G DD A Sbjct: 186 ILGLGGVGHMGVKIAKAMGHHVTVISSSNKKREEALQDLGADDYV-----IGSDQAKMSE 240 Query: 222 FPNGIDIYFENVG-GKMLDAVLVNMNMHGRIAVCGMISQYNLENQEGVHNLSNIIYKRIR 280 + +D + V L+ L + + G++ + G+ + N ++ +++ Sbjct: 241 LADSLDYVIDTVPVHHALEPYLSLLKLDGKLILMGV-----INNPLQFLTPLLMLGRKV- 294 Query: 281 IQGFVVSDFYDKYSKFLEFVLPHIREGKITYVEDVADGLEKAPEALVGLFHGKNVGKQVV 340 I G + + E +L +E ++ + +V ++ A L + VV Sbjct: 295 ITGSFIGSMKET-----EEMLEFCKEKGLSSIIEVVK-MDYVNTAFERLEKNDVRYRFVV 348 >1PL8-A nrPDB Length = 356 Score = 54.1 bits (128), Expect = 9e-08, Method: Composition-based stats. Identities = 52/342 (15%), Positives = 96/342 (28%), Gaps = 50/342 (14%) Query: 22 DFDFTTTTVELRVPEGTNSVLVKNLYLSCDPYMRIRMGKPDPSTAALAQAYTPGQPIQGY 81 D + P N VL++ + + + G G Sbjct: 18 DLRLENYPIPEPGP---NEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEASG- 73 Query: 82 GVSRIIESGHPDYKKGDLLWGIVAWEEYSVITPMTHAHF---------KIQHTDVPL--- 129 + S K GD + + + D L Sbjct: 74 -TVEKVGSSVKHLKPGDRVAIEPGAPREN-DEFCKMGRYNLSPSIFFCATPPDDGNLCRF 131 Query: 130 ---------------SYYTGLLGMPGMTAYAGFYEVCSPKEGETVYVSAASGAVGQLVGQ 174 ++ G L + ++ G V V A G +G + Sbjct: 132 YKHNAAFCYKLPDNVTFEEGAL-IEPLSVGIHACRRGGVTLGHKVLVCGA-GPIGMVTLL 189 Query: 175 LAKMMGC-YVVGSAGSKEKVDLLKTKFGFDDAFNYKEESDLTAALKRCFPNGI--DIYFE 231 +AK MG VV + S ++ K + G D +ES A K G ++ E Sbjct: 190 VAKAMGAAQVVVTDLSATRLSKAK-EIGADLVLQISKESPQEIARKVEGQLGCKPEVTIE 248 Query: 232 NVGGK-MLDAVLVNMNMHGRIAVCGMISQYNLENQEGVHNLSNIIYKRIRIQGFVVSDFY 290 G + + A + G + + G+ + +H + + I+G V + Sbjct: 249 CTGAEASIQAGIYATRSGGTLVLVGL--GSEMTTVPLLHA----AIREVDIKG--VFRYC 300 Query: 291 DKYSKFLEFVLPHIREGKITYVEDVADGLEKAPEALVGLFHG 332 + + + + + + + LEKA EA G Sbjct: 301 NTWPVAISMLAS--KSVNVKPLVTHRFPLEKALEAFETFKKG 340 >3RSH-A nrPDB Length = 251 Score = 52.1 bits (123), Expect = 4e-07, Method: Composition-based stats. Identities = 23/85 (27%), Positives = 36/85 (42%), Gaps = 5/85 (5%) Query: 155 EGETVYVSAASGAVGQLVGQLAKMMGCYVVGSAGSKEKVDLLKTKFGFDD---AFNYKEE 211 EG+ V+ AS +G+ + +L G V+G+A S+ + G + A N Sbjct: 11 EGKVALVTGASRGIGKAIAELLAERGAKVIGTATSESGAQAISDYLGDNGKGMALNVTNP 70 Query: 212 SDLTAALKRCFP--NGIDIYFENVG 234 + A LK G+DI N G Sbjct: 71 ESIEAVLKAITDEFGGVDILVNNAG 95 >3WLE-A nrPDB Length = 341 Score = 50.2 bits (118), Expect = 1e-06, Method: Composition-based stats. Identities = 51/238 (21%), Positives = 78/238 (32%), Gaps = 29/238 (12%) Query: 104 VAWEEYSVIT-PMTHAHFKIQHTDVPLSYYTGLLGMPGMTAYAGFYEVCSPKEGETVYVS 162 +++Y ++T P + D + +T Y ++ + + Sbjct: 128 GGYQQYLLVTRPRNLSRI----PDNVSADVAAASTDAVLTPYHAI-KMAQVSPTSNILLI 182 Query: 163 AASGAVGQLVGQLAKMMGCYVVGSAGSKEKVDLLKTKFGFDDAFNYKEESDLTAALKRCF 222 A G Q+AK G V KE D K K G D + ES Sbjct: 183 GAGGLG-GNAIQVAKAFGAKVTVLDKKKEARDQAK-KLGADAVYETLPES--------IS 232 Query: 223 PNGIDIYFENVG-GKMLDAVLVNMNMHGRIAVCGMISQYNLENQEGVHNLSNIIYKRIRI 281 P F+ V D + G I G L NL ++ + IRI Sbjct: 233 PGSFSACFDFVSVQATFDVCQKYVEPKGVIMPVG------LGAPNLSFNLGDLALREIRI 286 Query: 282 QGFVVSDFYDKYSKFLEFVLPHIREGKITYVEDVADGLEKAPEALVGLFHGKNVGKQV 339 G D L+ VL + EGK+ V A L++ PE + L + G+ V Sbjct: 287 LGSFWGTTND-----LDDVLKLVSEGKVKPVVRSAK-LKELPEYIEKLRNNAYEGRVV 338 >3TWO-A nrPDB Length = 348 Score = 49.8 bits (117), Expect = 2e-06, Method: Composition-based stats. Identities = 53/316 (16%), Positives = 100/316 (31%), Gaps = 66/316 (20%) Query: 72 YTPG--QPIQGYGVSRI---IESGHPDYKKGDLLWGIVAWE-----------------EY 109 + G I G+ ++ I + G +K GD++ G+ + Sbjct: 53 WKEGIYPMIPGHEIAGIIKEVGKGVKKFKIGDVV-GVGCFVNSCKACKPCKEHQEQFCTK 111 Query: 110 SVITPMTHAHFKIQHTDV---------------------PLSYYTGLLGMPGMTAYAGFY 148 V T F + PL LL G+T Y+ Sbjct: 112 VVFTYDCLDSFHDNEPHMGGYSNNIVVDENYVISVDKNAPLEKVAPLL-CAGITTYSPL- 169 Query: 149 EVCSPKEGETVYVSAASGAVGQLVGQLAKMMGCYVVGSAGSKEKVDLLKTKFGFDDAFNY 208 + +G V V A G +G + + A MG V A ++ K + + Sbjct: 170 KFSKVTKGTKVGV-AGFGGLGSMAVKYAVAMGAEVSVFARNEHKKQDALSMGVKHFYTDP 228 Query: 209 KEESDLTAALKRCFPNGIDIYFENVGGKMLDAVLVNMNMHGRIAVCGMISQYNLENQEGV 268 K+ + + P D L L + +G +A+ G+ +E + Sbjct: 229 KQCKEELDFIISTIPTHYD----------LKDYLKLLTYNGDLALVGLPP---VEVAPVL 275 Query: 269 HNLSNIIYKRIRIQGFVVSDFYDKYSKFLEFVLPHIREGKITYVEDVADGLEKAPEALVG 328 I ++ G ++ + + ++F + H I D+ G + A Sbjct: 276 SVFDFIHLGNRKVYGSLIGGIKET-QEMVDFSIKH----NIYPEIDLILG-KDIDTAYHN 329 Query: 329 LFHGKNVGKQVVVVAR 344 L HGK + V+ + + Sbjct: 330 LTHGKAKFRYVIDMKK 345 >1YQX-A nrPDB Length = 366 Score = 48.7 bits (114), Expect = 3e-06, Method: Composition-based stats. Identities = 38/217 (17%), Positives = 74/217 (34%), Gaps = 20/217 (9%) Query: 98 DLLWGIVAWEEYSVITPMTHAHFKIQHTD-VPLSYYTGLLGMPGMTAYAGFYEVCSPKEG 156 D + + V + I+ D +PL LL G+T Y+ + G Sbjct: 134 DGTITYGGYSNHMVAN----ERYIIRFPDNMPLDGGAPLL-CAGITVYSPLKYFGLDEPG 188 Query: 157 ETVYVSAASGAVGQLVGQLAKMMGCYVVGSAGSKEKVDLLKTKFGFDDAFNYKEESDLTA 216 + + + G + + AK G V + S K + FG D +++ + A Sbjct: 189 KHIGIVGLGGLG-HVAVKFAKAFGSKVTVISTSPSKKEEALKNFGADSFLVSRDQEQMQA 247 Query: 217 ALKRCFPNGIDIYFENVGGK-MLDAVLVNMNMHGRIAVCGMISQYNLENQEGVHNLSNII 275 A +D + V L + + HG++ + G E + S I Sbjct: 248 A-----AGTLDGIIDTVSAVHPLLPLFGLLKSHGKLILVGAP-----EKPLELPAFSLIA 297 Query: 276 YKRIRIQGFVVSDFYDKYSKFLEFVLPHIREGKITYV 312 ++I + G + + + ++F H I + Sbjct: 298 GRKI-VAGSGIGGMKET-QEMIDFAAKHNITADIEVI 332 >6DKH-A nrPDB Length = 346 Score = 48.3 bits (113), Expect = 5e-06, Method: Composition-based stats. Identities = 34/226 (15%), Positives = 72/226 (31%), Gaps = 23/226 (10%) Query: 104 VAWEEYSVITPMTHAHFKIQHTDVPLSYYTGLLGMPGMTAYAGFYEVCSPKEGETVYVSA 163 + Y ++ + + + +++ L A ++ + G+ V++S Sbjct: 127 GGFTRYKMVETSQCVPYPAKADEKVMAFAEPLA-----VAIHAAHQAGELQ-GKRVFISG 180 Query: 164 ASGAVGQLVGQLAKMMGCYVVGSAGSKEKVDLLKTKFGFDDAFNYKEESDLTAALKRCFP 223 G +G L+ K +G + A + L + G D N + D+ Sbjct: 181 V-GPIGCLIVSAVKTLGAAEIVCADVSPRSLSLGKEMGADVLVN-PQNDDMDHWKAE--- 235 Query: 224 NGI-DIYFENVGGKML-DAVLVNMNMHGRIAVCGMISQYNLENQEGVHNLSNIIYKRIRI 281 G D+ FE G + L G + GM + +I K I + Sbjct: 236 KGYFDVSFEVSGHPSSVNTCLEVTRARGVMVQVGM------GGAMAEFPMMTLIGKEISL 289 Query: 282 QGFVVSDFYDKYSKFLEFVLPHIREGKITYVEDVADGLEKAPEALV 327 +G F +++ + ++ + + EAL Sbjct: 290 RGSF--RFTSEFNTAVSWLANGVINP--LPLLSAEYPFTDLEEALR 331 >6C49-A nrPDB Length = 350 Score = 47.9 bits (112), Expect = 6e-06, Method: Composition-based stats. Identities = 41/270 (15%), Positives = 82/270 (30%), Gaps = 25/270 (9%) Query: 72 YTPGQPIQGYGVSRIIESGHPDYKKGDLLWGIVAWEEYSVITPMTHAHFKIQHTDVPLSY 131 +T + ++ + + V A + D Sbjct: 99 WTAESCQACDECIGGQQVLCTGENIATIVGHAGGFADK-VRAGWQWAIPLPEDLD---PE 154 Query: 132 YTGLLGMPGMTAYAGFYEVCSPKEGETVYVSAASGAVGQLVGQLAKMMGCYVVGSAGSKE 191 G L G+T + + + V V G + +L K GC + + + + Sbjct: 155 SAGPLLCGGITVFDPLLK-HKIQATHHVGVIGIGGLG-HIAIKLLKAWGCEITAFSSNPD 212 Query: 192 KVDLLKTKFGFDDAFNYKEESDLTAALKRCFPNGIDIYFENVGGK-MLDAVLVNMNMHGR 250 K + LK G D N ++ T A+K D+ V A + + +G Sbjct: 213 KTEELK-AMGADHVVNSRD----TEAVKAQKGK-FDLLLSTVNVTLNWRAFISTLAPNGS 266 Query: 251 IAVCGMISQYNLENQEGVHNLSNIIYKRIRIQGFVVSDFYDKYSKFLEFVLPHIREGKIT 310 + G L + ++ ++I + G L +L KI Sbjct: 267 LHFLG------LTLEPVPVSVGSLIDGAKSVTGSPTGS-----PAALRQLLKFAARKKIA 315 Query: 311 YVEDVADGLEKAPEALVGLFHGKNVGKQVV 340 ++ + + EA+ L G+ + V+ Sbjct: 316 PQIEL-FPMSQLNEAIERLHSGQARYRIVL 344 >3QE3-A nrPDB Length = 355 Score = 47.5 bits (111), Expect = 9e-06, Method: Composition-based stats. Identities = 37/195 (18%), Positives = 67/195 (34%), Gaps = 16/195 (8%) Query: 151 CSPKEGETVYVSAASGAVGQLVGQLAKMMGC-YVVGSAGSKEKVDLLKTKFGFDDAFNYK 209 G V V A G +G + AK MG VV + S ++ K + G D Sbjct: 166 AGVTLGNKVLVCGA-GPIGLVNLLAAKAMGAAQVVVTDLSASRLSKAK-EVGADFILEIS 223 Query: 210 EESDLTAALKRCF--PNGIDIYFENVG-GKMLDAVLVNMNMHGRIAVCGMISQYNLENQE 266 ES A K + ++ E G + A + + G + + G+ + + Sbjct: 224 NESPEEIAKKVEGLLGSKPEVTIECTGVETSIQAGIYATHSGGTLVLVGL--GSEMTSVP 281 Query: 267 GVHNLSNIIYKRIRIQGFVVSDFYDKYSKFLEFVLPHIREGKITYVEDVADGLEKAPEAL 326 VH + + I+G V + + + + + + + + LEKA EA Sbjct: 282 LVHA----ATREVDIKG--VFRYCNTWPMAISMLAS--KSVNVKPLVTHRFPLEKALEAF 333 Query: 327 VGLFHGKNVGKQVVV 341 G + + Sbjct: 334 ETSKKGLGLKVMIKC 348 >1Q7C-A nrPDB Length = 244 Score = 47.5 bits (111), Expect = 9e-06, Method: Composition-based stats. Identities = 19/85 (22%), Positives = 36/85 (42%), Gaps = 5/85 (5%) Query: 155 EGETVYVSAASGAVGQLVGQLAKMMGCYVVGSAGSKEKVDLLKTKFGFDD---AFNYKEE 211 EG+ V+ AS +G+ + + G V+G+A S+ + G + N + Sbjct: 4 EGKIALVTGASRGIGRAIAETLAARGAKVIGTATSENGAQAISDYLGANGKGLMLNVTDP 63 Query: 212 SDLTAALK--RCFPNGIDIYFENVG 234 + + + L+ R +DI N G Sbjct: 64 ASIESVLEKIRAEFGEVDILVNNAG 88 >5Z0C-A nrPDB Length = 374 Score = 45.6 bits (106), Expect = 3e-05, Method: Composition-based stats. Identities = 31/202 (15%), Positives = 66/202 (32%), Gaps = 17/202 (8%) Query: 118 AHFKIQHTD-VPLSYYTGLLGMPGMTAYAGFYEVCSPKEGETVYVSAASGAVGQLVGQLA 176 HF ++ D +PL LL G+T Y+ + G +G + + A Sbjct: 147 EHFAVRIPDALPLDSAAPLL-CAGITVYSPLR-YYGLDKPGLHVGVVGLGGLGHMAVKFA 204 Query: 177 KMMGCYVVGSAGSKEKVDLLKTKFGFDDAFNYKEESDLTAALKRCFPNGIDIYFENVGGK 236 K G V + S K + + G + + AA+ +D + V Sbjct: 205 KAFGVKVTVVSTSPAKKEDAISGLGAHSFILSTDAEQMQAAVGT-----MDGIIDTVSAS 259 Query: 237 -MLDAVLVNMNMHGRIAVCGMISQYNLENQEGVHNLSNIIYKRIRIQGFVVSDFYDKYSK 295 L ++ + HG++ + G + + ++ R + G + + + Sbjct: 260 HPLPPLISLLKSHGKLVMVGD------PPKPLELPVFPLLLGRKMVAGSAIGGMKET-QE 312 Query: 296 FLEFVLPHIREGKITYVEDVAD 317 ++F + V + Sbjct: 313 MIDFAAKEGVRADV-EVIPMDY 333 >4OAQ-A nrPDB Length = 367 Score = 44.8 bits (104), Expect = 5e-05, Method: Composition-based stats. Identities = 29/159 (18%), Positives = 48/159 (30%), Gaps = 12/159 (7%) Query: 102 GIVAWEEYSVITPMTHAHFKIQHTDVPLSYYTGLLGMPGMTAYAGFYEVCSPKEGETVYV 161 + +S+ F I D+P SY L+ G+T ++ Sbjct: 135 TQGGYSSHSIAD--EKFVFAIPE-DLPSSYGAPLM-CAGITVFSPLIRNLGLDARGKNVG 190 Query: 162 SAASGAVGQLVGQLAKMMGCYVVGSAGSKEKVDLLKTKFGFDDAFNYKEESDLTAALKRC 221 G +G L Q A MG V + S K + K G D E+ + Sbjct: 191 IIGIGGLGHLALQFANAMGANVTAFSRSSSKKEQA-MKLGAHDFVATGED----KTWYKN 245 Query: 222 FPNGIDIYFENVGGK---MLDAVLVNMNMHGRIAVCGMI 257 + + D G L L + + + G+ Sbjct: 246 YDDHFDFILNCASGIDGLNLSEYLSTLKVDKKFVSVGLP 284 >3D3W-A nrPDB Length = 244 Score = 43.7 bits (101), Expect = 1e-04, Method: Composition-based stats. Identities = 15/93 (16%), Positives = 27/93 (29%) Query: 155 EGETVYVSAASGAVGQLVGQLAKMMGCYVVGSAGSKEKVDLLKTKFGFDDAFNYKEESDL 214 G V V+ A +G+ Q G VV + ++ +D L + + Sbjct: 6 AGRRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQADLDSLVRECPGIEPVCVDLGDWE 65 Query: 215 TAALKRCFPNGIDIYFENVGGKMLDAVLVNMNM 247 +D+ N +L L Sbjct: 66 ATERALGSVGPVDLLVNNAAVALLQPFLEVTKE 98 >3F9I-A nrPDB Length = 249 Score = 42.5 bits (98), Expect = 3e-04, Method: Composition-based stats. Identities = 17/94 (18%), Positives = 37/94 (39%), Gaps = 6/94 (6%) Query: 156 GETVYVSAASGAVGQLVGQLAKMMGCYVVGSAGSKEKVDLLKTKFGFD---DAFNYKEES 212 G+T ++ AS +G + +L +G V+ S ++EK+ L + + N + Sbjct: 14 GKTSLITGASSGIGSAIARLLHKLGSKVIISGSNEEKLKSLGNALKDNYTIEVCNLANKE 73 Query: 213 DLTAALKRCFPNGIDIYFENVGGKMLDAVLVNMN 246 + + + + I G D + + M Sbjct: 74 ECSNLISKTSNLDI---LVCNAGITSDTLAIRMK 104 >5CDY-A nrPDB Length = 244 Score = 41.7 bits (96), Expect = 5e-04, Method: Composition-based stats. Identities = 19/86 (22%), Positives = 37/86 (43%), Gaps = 7/86 (8%) Query: 155 EGETVYVSAASGAVGQLVGQLAKMMGCYVVGSAGSKEKVDLLKTKFGFDD------AFNY 208 EG+ V+ AS +G+ + +L G V+G+A S++ + + G + + Sbjct: 4 EGKIALVTGASRGIGRAIAELLVERGACVIGTATSEKGAEAISAYLGENGKGLMLNVVDP 63 Query: 209 KEESDLTAALKRCFPNGIDIYFENVG 234 + A ++ F +DI N G Sbjct: 64 TSIDTVLATIRAEFGE-VDILVNNAG 88 >5VKT-A nrPDB Length = 362 Score = 41.0 bits (94), Expect = 8e-04, Method: Composition-based stats. Identities = 29/137 (21%), Positives = 50/137 (36%), Gaps = 8/137 (5%) Query: 124 HTDVPLSYYTGLLGMPGMTAYAGFYEVCSPKEGETVYVSAASGAVGQLVGQLAKMMGCYV 183 +PL LL G+T Y+ + + G+ + V G + + AK G V Sbjct: 152 PESLPLDGAAPLL-CAGVTVYSPMAQYALNEPGKHLGVVGLGGLG-HMAVKFAKAFGMTV 209 Query: 184 VGSAGSKEKVDLLKTKFGFDDAFNYKEESDLTAALKRCFPNGIDIYFENV-GGKMLDAVL 242 + S K D + G D + + + AA +D + V G + +L Sbjct: 210 TVISSSPGKRDEALGRLGADAFLVSHDAAQMKAAAAT-----LDGIIDTVSAGHQIVPLL 264 Query: 243 VNMNMHGRIAVCGMISQ 259 + G++ V G S Sbjct: 265 ALLKPMGQMVVVGAPST 281 >3EMK-A nrPDB Length = 246 Score = 41.0 bits (94), Expect = 8e-04, Method: Composition-based stats. Identities = 19/85 (22%), Positives = 32/85 (37%), Gaps = 7/85 (8%) Query: 156 GETVYVSAASGAVGQLVGQLAKMMGCYVVGSAGSKEKVDLLKTKFGFDDAFNYKEESDLT 215 G V+ A+G +G+ + + G V +EK+ L + G + F + Sbjct: 7 GRKALVTGATGGLGEAIARALHAQGAIVGLHGTREEKLKELAAELG-ERIFVFPANLSDR 65 Query: 216 AALKRCFPN------GIDIYFENVG 234 A+K G+DI N G Sbjct: 66 EAVKALGQKAEEEMGGVDILVNNAG 90 >4M8S-A nrPDB Length = 248 Score = 39.4 bits (90), Expect = 0.002, Method: Composition-based stats. Identities = 25/159 (15%), Positives = 49/159 (30%), Gaps = 29/159 (18%) Query: 155 EGETVYVSAASGAVGQLVGQLAKMMGCYVVGSAGSKEKVDLLKTKF----GFDDAFNYKE 210 G+ V+ AS +G + G V+G+A S+ + + G N E Sbjct: 7 SGKIALVTGASRGIGAAIADTLAAAGAKVIGTATSESGAAAISERLAQWGGEGRVLNSAE 66 Query: 211 ESDLTAALK--RCFPNGIDIYFENVG---------------GKMLDAVLVNMNMHGRIAV 253 + + +DI N G ++ L ++ + + Sbjct: 67 PETVENLIADIEKTFGKLDILVNNAGITRDNLLMRMKEEEWDDIMQVNLKSVFRASKAVL 126 Query: 254 CGMISQ--------YNLENQEGVHNLSNIIYKRIRIQGF 284 GM+ Q ++ G +N + + GF Sbjct: 127 RGMMKQRAGRIINITSVVGVMGNAGQTNYAAAKAGLIGF 165 >3PWS-A nrPDB Length = 366 Score = 39.1 bits (89), Expect = 0.003, Method: Composition-based stats. Identities = 21/98 (21%), Positives = 35/98 (35%), Gaps = 7/98 (7%) Query: 156 GETVYVSAASGAVGQLVGQLAKMMGCYVVGSAGSKEKVDLLKTKFGFDDAFNYKEESDLT 215 G TV V A+GAVG Q+ KM+ + +K+ L + + +K++ Sbjct: 2 GYTVAVVGATGAVG---AQMIKMLEESTLPI----DKIRYLASARSAGKSLKFKDQDITI 54 Query: 216 AALKRCFPNGIDIYFENVGGKMLDAVLVNMNMHGRIAV 253 G+DI + G G + V Sbjct: 55 EETTETAFEGVDIALFSAGSSTSAKYAPYAVKAGVVVV 92 >5T5Q-A nrPDB Length = 247 Score = 38.7 bits (88), Expect = 0.004, Method: Composition-based stats. Identities = 18/87 (20%), Positives = 34/87 (39%), Gaps = 7/87 (8%) Query: 155 EGETVYVSAASGAVGQLVGQLAKMMGCYVVGSAGSKEKVDLLKTKFGFDDAFNYKEESDL 214 E T+ ++ A+G +G+ + +L G +V + +E +D G + + Sbjct: 8 ENRTLVLTGANGGIGRAIAELFHASGANLVLTDLDREGLDAFAASLGSPERIATIKADAS 67 Query: 215 TA-------ALKRCFPNGIDIYFENVG 234 +A AL GID + G Sbjct: 68 SADDAEKTVALAMERFGGIDFLVPSAG 94 >1BDB-A nrPDB Length = 277 Score = 38.3 bits (87), Expect = 0.004, Method: Composition-based stats. Identities = 32/166 (19%), Positives = 58/166 (34%), Gaps = 15/166 (9%) Query: 155 EGETVYVSAASGAVGQLVGQLAKMMGCYVVGSAGSKEKVDLLKTKFGFDD---AFNYKEE 211 +GE V ++ + +G+ + G V S E++ L+T G + + + Sbjct: 4 KGEAVLITGGASGLGRALVDRFVAEGAKVAVLDKSAERLAELETDHGDNVLGIVGDVRSL 63 Query: 212 SDLTAALKRCFPN--GIDIYFENVGGKMLDAVLVNMNMHGRIAVCGMISQYNLEN----- 264 D A RC ID N G LV++ A + N++ Sbjct: 64 EDQKQAASRCVARFGKIDTLIPNAGIWDYSTALVDLPEESLDAAFDEVFHINVKGYIHAV 123 Query: 265 ----QEGVHNLSNIIYKRIRIQGFVVSDFYDKYSKFLEFVLPHIRE 306 V + N+I+ I GF + Y+ ++ +RE Sbjct: 124 KACLPALVASRGNVIFT-ISNAGFYPNGGGPLYTAAKHAIVGLVRE 168 >3PPI-A nrPDB Length = 281 Score = 38.3 bits (87), Expect = 0.005, Method: Composition-based stats. Identities = 23/104 (22%), Positives = 37/104 (35%), Gaps = 4/104 (3%) Query: 155 EGETVYVSAASGAVGQLVGQLAKMMGCYVVGSAGSKEKVDLLKTKFGFDDAF---NYKEE 211 EG + VS +G +G+ + G VV + + EK L + G F N E Sbjct: 29 EGASAIVSGGAGGLGEATVRRLHADGLGVVIADLAAEKGKALADELGNRAEFVSTNVTSE 88 Query: 212 SDLTAALKRCFPNGIDIYFENVGGKMLDAVLVNMNMHGRIAVCG 255 + AA++ G + + V + G A G Sbjct: 89 DSVLAAIEAANQLG-RLRYAVVAHGGFGVAQRIVQRDGSPADMG 131 >3GRP-A nrPDB Length = 266 Score = 38.3 bits (87), Expect = 0.005, Method: Composition-based stats. Identities = 22/86 (25%), Positives = 35/86 (40%), Gaps = 9/86 (10%) Query: 156 GETVYVSAASGAVGQLVGQLAKMMGCYVVGSAGSKE-KVDLLKTKFGFDDAF------NY 208 G V+ A+G +G+ + + G +VG G++E K+ + G D + Sbjct: 27 GRKALVTGATGGIGEAIARCFHAQGA-IVGLHGTREDKLKEIAADLGKDVFVFSANLSDR 85 Query: 209 KEESDLTAALKRCFPNGIDIYFENVG 234 K L +R GIDI N G Sbjct: 86 KSIKQLAEVAEREM-EGIDILVNNAG 110 >5E4R-A nrPDB Length = 490 Score = 38.3 bits (87), Expect = 0.005, Method: Composition-based stats. Identities = 40/213 (18%), Positives = 71/213 (33%), Gaps = 24/213 (11%) Query: 148 YEVCSPKEGETVYVSAASGAVGQLVGQLAKMMGCYVVGSAGSKEKVDLLKTKFGFDDAFN 207 YE+ SG Q +AK +GC G S K + FG Sbjct: 141 YEMGGGVPALVAVYQNVSGEALQKALAIAKGIGCARAGVIESTFKEETETDLFGEQVILV 200 Query: 208 -------------YKEESDLTAALKRCFPNGIDIYFENVGGKMLDAVLVNMNMHGRIAVC 254 EE N + + + + K L +L ++ A Sbjct: 201 GGIMELIKASFETLVEEGYQPEVAYFETVNELKLIVDLIYEKGLTGMLRAVSD---TAKY 257 Query: 255 GMISQYNLENQEGVHNLSNIIYKRIRIQGFVVSDFYDKYSKFLEFVLPHIREGKITYVED 314 G I+ + V + I+ +RIR G ++ +Y + + V + E + + +E Sbjct: 258 GGITVGKFIIDKSVRDKMKIVLERIR-SGEFAREWIKEYERGMPTVFKELSELEGSTIET 316 Query: 315 VADGLEKAPEALVGLFHGKN-----VGKQVVVV 342 V L + G+ + G+QV++V Sbjct: 317 VGRKLREM--MFRGMKQISSHETDLFGEQVILV 347 >4XDZ-A nrPDB Length = 343 Score = 37.9 bits (86), Expect = 0.006, Method: Composition-based stats. Identities = 35/188 (18%), Positives = 61/188 (32%), Gaps = 17/188 (9%) Query: 148 YEVCSPKEGETVYVSAASGAVGQLVGQLAKMMGCYVVGSAGSKEKVDLLKTKFGFDDAFN 207 YE+ SG Q +AK +GC G S K + FG Sbjct: 141 YEMGGGVPALVAVYQNVSGEALQKALAIAKGIGCARAGVIESTFKEETETDLFGEQVILV 200 Query: 208 -------------YKEESDLTAALKRCFPNGIDIYFENVGGKMLDAVLVNMNMHGRIAVC 254 EE N + + + + K L +L ++ A Sbjct: 201 GGIMELIKASFETLVEEGYQPEVAYFETVNELKLIVDLIYEKGLTGMLRAVSD---TAKY 257 Query: 255 GMISQYNLENQEGVHNLSNIIYKRIRIQGFVVSDFYDKYSKFLEFVLPHIREGKITYVED 314 G I+ + V + I+ +RIR G ++ +Y + + V + E + + +E Sbjct: 258 GGITVGKFIIDKSVRDKMKIVLERIR-SGEFAREWIKEYERGMPTVFKELSELEGSTIET 316 Query: 315 VADGLEKA 322 V L + Sbjct: 317 VGRKLREM 324 >3VZS-A nrPDB Length = 257 Score = 37.5 bits (85), Expect = 0.009, Method: Composition-based stats. Identities = 21/98 (21%), Positives = 32/98 (32%), Gaps = 12/98 (12%) Query: 160 YVSAASGAVGQLVGQLAKMMGCYVVGSAG----SKEKVDLLKTKFGFD------DAFNYK 209 YV+ G +G + Q G VV G +EK + GFD + ++ Sbjct: 18 YVTGGMGGIGTAICQRLAKDGFRVVAGCGPNSPRREKWLEQQKALGFDFIASEGNVADWD 77 Query: 210 EESDLTAALKRCFPNGIDIYFENVGGKMLDAVLVNMNM 247 +K +D+ N G D V M Sbjct: 78 STKTAFDKVKSEVGE-VDVLINNAG-ITRDVVFRKMTR 113 >4BO1-A nrPDB Length = 269 Score = 36.7 bits (83), Expect = 0.013, Method: Composition-based stats. Identities = 21/101 (20%), Positives = 38/101 (37%), Gaps = 7/101 (6%) Query: 155 EGETVYVSAASGAVGQLVGQLAKMMGCYVVGSAGSKEKVDLLKTKF------GFDDAFNY 208 +G+ V+ AS +GQ + +G V+G+A S + + G + Sbjct: 26 QGKVALVTGASRGIGQAIALELGRLGAVVIGTATSASGAEKIAETLKANGVEGAGLVLDV 85 Query: 209 KEESDLTAALKRCFPN-GIDIYFENVGGKMLDAVLVNMNMH 248 + + A L+ + G + N G D +LV M Sbjct: 86 SSDESVAATLEHIQQHLGQPLIVVNNAGITRDNLLVRMKDD 126 >3EZL-A nrPDB Length = 256 Score = 36.7 bits (83), Expect = 0.016, Method: Composition-based stats. Identities = 23/99 (23%), Positives = 34/99 (34%), Gaps = 12/99 (12%) Query: 160 YVSAASGAVGQLVGQLAKMMGCYVVGSAG--SKEKVDLLKTK--FGFD------DAFNYK 209 YV+ G +G + Q G VV G S +V L+ + GFD + ++ Sbjct: 17 YVTGGMGGIGTSICQRLHKDGFRVVAGCGPNSPRRVKWLEDQKALGFDFYASEGNVGDWD 76 Query: 210 EESDLTAALKRCFPNGIDIYFENVGGKMLDAVLVNMNMH 248 +K ID+ N G D V M Sbjct: 77 STKQAFDKVKAEVGE-IDVLVNNAG-ITRDVVFRKMTRE 113 >3DWF-A nrPDB Length = 276 Score = 36.0 bits (81), Expect = 0.024, Method: Composition-based stats. Identities = 17/43 (39%), Positives = 27/43 (62%), Gaps = 2/43 (4%) Query: 155 EGETVYVSAASGAVG-QLVGQLAKMMGCYVVGSAGSKEKVDLL 196 +G+ V V+ AS +G ++ LAKM G +VV +A SKE + + Sbjct: 10 QGKKVIVTGASKGIGREIAYHLAKM-GAHVVVTARSKEALQKV 51 >2UVD-A nrPDB Length = 246 Score = 36.0 bits (81), Expect = 0.024, Method: Composition-based stats. Identities = 23/89 (25%), Positives = 38/89 (42%), Gaps = 9/89 (10%) Query: 155 EGETVYVSAASGAVGQL-VGQLAKMMGCYVVGSAGSKEKVDLLKT---KFGFDDA---FN 207 +G+ V+ AS +G+ LAK VV AG+++K + + K G D + Sbjct: 3 KGKVALVTGASRGIGRAIAIDLAKQGANVVVNYAGNEQKANEVVDEIKKLGSDAIAVRAD 62 Query: 208 YKEESDLTAALKRCFP--NGIDIYFENVG 234 D+T +K+ +DI N G Sbjct: 63 VANAEDVTNMVKQTVDVFGQVDILVNNAG 91 >5PGZ-A nrPDB Length = 276 Score = 36.0 bits (81), Expect = 0.026, Method: Composition-based stats. Identities = 13/45 (28%), Positives = 26/45 (57%) Query: 155 EGETVYVSAASGAVGQLVGQLAKMMGCYVVGSAGSKEKVDLLKTK 199 +G+ V V+ AS +G+ + MG +VV +A S+E + + ++ Sbjct: 17 QGKKVIVTGASKGIGREMAYHLSKMGAHVVLTARSEEGLQKVVSR 61 >2DPH-A nrPDB Length = 398 Score = 35.6 bits (80), Expect = 0.033, Method: Composition-based stats. Identities = 31/197 (15%), Positives = 64/197 (32%), Gaps = 16/197 (8%) Query: 91 HPDYKKGDLLWGIVAW----EEYSVITPMTHAHFKIQHTDVPLSYYTGLLGMPGM--TAY 144 +PD G + + W EY ++ + K + + L + + T + Sbjct: 116 NPDADLGAFGFDLKGWSGGQAEYVLVPYADYMLLKFGDKEQAMEKIKDLTLISDILPTGF 175 Query: 145 AGFYEVCSPKEGETVYVSAASGAVGQLVGQLAKMMGCYVVGSAGSKEKVDLLKTKFGFDD 204 G K G VY+ A +G VG+ A+++G V + L + GF+ Sbjct: 176 HGCV-SAGVKPGSHVYI-AGAGPVGRCAAAGARLLGAACVIVGDQNPERLKLLSDAGFE- 232 Query: 205 AFNYKEESDLTAALKRCFPNG-IDIYFENVG------GKMLDAVLVNMNMHGRIAVCGMI 257 + + + L + + +D + VG G + N ++ V Sbjct: 233 TIDLRNSAPLRDQIDQILGKPEVDCGVDAVGFEAHGLGDEANTETPNGALNSLFDVVRAG 292 Query: 258 SQYNLENQEGVHNLSNI 274 + + + Sbjct: 293 GAIGIPGIYVGSDPDPV 309 >5YWN-A nrPDB Length = 334 Score = 34.8 bits (78), Expect = 0.052, Method: Composition-based stats. Identities = 19/46 (41%), Positives = 26/46 (56%) Query: 158 TVYVSAASGAVGQLVGQLAKMMGCYVVGSAGSKEKVDLLKTKFGFD 203 +V+VS A+G + Q + L G VVGS S+EK LK +G D Sbjct: 4 SVFVSGATGYLAQQIIALVLSKGYKVVGSVRSEEKGANLKKLYGDD 49 >4PVC-A nrPDB Length = 342 Score = 34.8 bits (78), Expect = 0.054, Method: Composition-based stats. Identities = 21/88 (23%), Positives = 33/88 (37%), Gaps = 5/88 (5%) Query: 157 ETVYVSAASGAVGQLVGQLAKMMGCYVVGSAGSKEKVDLLKTKFG-----FDDAFNYKEE 211 +V+VS A+G + Q + L V+GSA S+EK + L FG + + Sbjct: 1 MSVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISK 60 Query: 212 SDLTAALKRCFPNGIDIYFENVGGKMLD 239 D + + I I D Sbjct: 61 LDAFDHVFQKHGKDIKIVLHTASPFCFD 88 >5YSS-A nrPDB Length = 256 Score = 34.4 bits (77), Expect = 0.069, Method: Composition-based stats. Identities = 14/85 (16%), Positives = 32/85 (37%), Gaps = 6/85 (7%) Query: 156 GETVYVSAASGAVGQLVGQLAKMMGCYVV----GSAGSKEKVDLLKTKFGFDDAFNYKEE 211 G+T V+ ++ +G + Q+ G ++ G + + K + +E Sbjct: 5 GKTALVTGSTSGIGLGIAQVLAQAGATLILNGFGDVDAAKDAVAQYGKTPGYHGADLSDE 64 Query: 212 SDLTAALKRC--FPNGIDIYFENVG 234 + + ++ G+DI N G Sbjct: 65 AQIADMMRYAESEFGGVDILINNAG 89 >1ZZE-A nrPDB Length = 342 Score = 34.4 bits (77), Expect = 0.076, Method: Composition-based stats. Identities = 37/200 (18%), Positives = 56/200 (28%), Gaps = 21/200 (10%) Query: 148 YEVCSPKEGETVYVSAASGAVGQLVGQLAKMMGCYVVGSAGSKEKVDLLKTKFGFDDAFN 207 + EG V V+ A+G V V + G V G+A S K+ L+ ++ Sbjct: 3 IDNAVLPEGSLVLVTGANGFVASHVVEQLLEHGYKVRGTARSASKLANLQKRWDAK---- 58 Query: 208 YKEESDLTAALKRCFPNGIDIYFENVGGKMLDAVLVNMNMHGRIAVCGMISQYNLENQEG 267 Y + D + G A +V+ + V I + Sbjct: 59 YPGRFETAVVEDMLKQGAYDEVIKGAAGVAHIASVVSFSNKYDEVVTPAIGGTLNALRAA 118 Query: 268 VHNLSNIIYKRIRIQGFVVSDFYDK------YSKFLEFVLPHIREGKITYVEDVADGL-- 319 S KR + VS K Y + L I + K D L Sbjct: 119 AATPS---VKRFVLTSSTVSALIPKPNVEGIYLDEKSWNLESIDKAKTLPESDPQKSLWV 175 Query: 320 ------EKAPEALVGLFHGK 333 E A + K Sbjct: 176 YAASKTEAELAAWKFMDENK 195 >5H83-A nrPDB Length = 360 Score = 34.4 bits (77), Expect = 0.082, Method: Composition-based stats. Identities = 51/300 (17%), Positives = 95/300 (31%), Gaps = 53/300 (17%) Query: 37 GTNSVLVKNLYL-SCDPYMRIRMGKPDPSTAALAQAYTPGQPIQGYGVSRIIESGHPDYK 95 G N V K LY +C+ + + K + + G I G V I S +K Sbjct: 38 GENDVQFKVLYCGTCNYDLEMSTNKFGMTK----YPFVIGHEIVG--VVTEIGSKVQKFK 91 Query: 96 KGDLLWGIVAW-----EEYSVITPMTHAHFKIQHTDVPLSYYTG---------------- 134 GD + G+ + + + + + K++ TD G Sbjct: 92 VGDKV-GVGGFVGACEKCEMCVNGVENNCSKVESTDGHFGNNFGGCCNIMVVNEKYAVVW 150 Query: 135 ----------LLGMPGMTAYAGFYEVCSPKEGETVYVSAASGAVGQLVGQLAKMMGCYVV 184 L G+T Y+ K G + ++ G L + AK G V Sbjct: 151 PENLPLHSGVPLLCAGITTYSPLRRYGLDKPGLNIGIAGLGGLG-HLAIRFAKAFGAKVT 209 Query: 185 GSAGSKEKVDLLKTKFGFDDAFNYKEESDLTAALKRCFPNGIDIYFENVG-GKMLDAVLV 243 + S +K KFG D ++ A +D + + + L Sbjct: 210 LISSSVKKKREALEKFGVDSFLLNSNPEEMQGAYGT-----LDGIIDTMPVAHSIVPFLA 264 Query: 244 NMNMHGRIAVCGMISQYNLENQEGVHNLSNIIYKRIRIQGFVVSDFYDKYSKFLEFVLPH 303 + G++ + G+ E V + ++ ++ I G + + ++F H Sbjct: 265 LLKPLGKLIILGVP-----EEPFEVPAPALLMGGKL-IAGSAAGSMKET-QEMIDFAAKH 317 >5B6K-A nrPDB Length = 366 Score = 33.7 bits (75), Expect = 0.12, Method: Composition-based stats. Identities = 26/80 (32%), Positives = 35/80 (43%), Gaps = 6/80 (7%) Query: 158 TVYVSAASGAVGQLVGQLAKMMGCYVVGSAGSKEKVDLLKTKFGFDDAFNYKEESDLTAA 217 TV+VS A+G + Q V + V+GS S EK D LK FNY+ D++ Sbjct: 23 TVFVSGATGFIAQHVVRQLLDQNYKVIGSVRSAEKGDHLKNVIFKGGDFNYEIVKDISD- 81 Query: 218 LKRCFPNGIDIYFENVGGKM 237 P D FE G + Sbjct: 82 -----PTAFDHVFEKHGKDI 96 >2Q2Q-A nrPDB Length = 255 Score = 33.7 bits (75), Expect = 0.14, Method: Composition-based stats. Identities = 22/125 (17%), Positives = 45/125 (36%), Gaps = 21/125 (16%) Query: 155 EGETVYVSAASGAVGQLVGQLAKMMGCYVVGSAGSKEKVDLLKTKFGFDDAFNYKEESDL 214 +G+T V+ ++ +G + Q+ G +V + L + A ++ + Sbjct: 3 KGKTALVTGSTSGIGLGIAQVLARAGANIVLNGFGDPAPALAEIARHGVKAVHHPADLSD 62 Query: 215 TAALKRCFP------NGIDIYFENVG---------------GKMLDAVLVNMNMHGRIAV 253 A ++ F G+DI N G K++ L + R+A+ Sbjct: 63 VAQIEALFALAEREFGGVDILVNNAGIQHVAPVEQFPLESWDKIIALNLSAVFHGTRLAL 122 Query: 254 CGMIS 258 GM + Sbjct: 123 PGMRA 127 >4HP8-A nrPDB Length = 247 Score = 33.3 bits (74), Expect = 0.15, Method: Composition-based stats. Identities = 21/81 (25%), Positives = 31/81 (38%), Gaps = 1/81 (1%) Query: 155 EGETVYVSAASGAVGQLVGQLAKMMGCYVVGSAGSKEKVDL-LKTKFGFDDAFNYKEESD 213 EG V+ A+ +GQ + G VV +A L + K G + + + +D Sbjct: 8 EGRKALVTGANTGLGQAIAVGLAAAGAEVVCAARRAPDETLDIIAKDGGNASALLIDFAD 67 Query: 214 LTAALKRCFPNGIDIYFENVG 234 AA G DI N G Sbjct: 68 PLAAKDSFTDAGFDILVNNAG 88 >1YXM-A nrPDB Length = 303 Score = 33.3 bits (74), Expect = 0.15, Method: Composition-based stats. Identities = 15/101 (14%), Positives = 36/101 (35%), Gaps = 13/101 (12%) Query: 152 SPKEGETVYVSAASGAVGQLVGQLAKMMGCYVVGSAGSKEKVDLLKTKFGFDDA------ 205 +G+ V+ + +G+ + + +G VV ++ E++ + + Sbjct: 14 GLLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQAR 73 Query: 206 -----FNYKEESDLTAALKRC--FPNGIDIYFENVGGKMLD 239 N + E ++ +K I+ N GG+ L Sbjct: 74 VIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLS 114 >1AE1-A nrPDB Length = 273 Score = 33.3 bits (74), Expect = 0.16, Method: Composition-based stats. Identities = 16/90 (17%), Positives = 28/90 (31%), Gaps = 11/90 (12%) Query: 155 EGETVYVSAASGAVGQLVGQLAKMMGCYVVGSAGSKEKVDLLKTKFGFDDAFN------- 207 +G T V+ S +G + + +G V + EK + + N Sbjct: 20 KGTTALVTGGSKGIGYAIVEELAGLGARV-YTCSRNEKELDECLEIWREKGLNVEGSVCD 78 Query: 208 ---YKEESDLTAALKRCFPNGIDIYFENVG 234 E L + F ++I N G Sbjct: 79 LLSRTERDKLMQTVAHVFDGKLNILVNNAG 108 >2PNF-A nrPDB Length = 248 Score = 33.3 bits (74), Expect = 0.18, Method: Composition-based stats. Identities = 16/89 (17%), Positives = 34/89 (38%), Gaps = 9/89 (10%) Query: 155 EGETVYVSAASGAVGQLVGQLAKMMGCYVVGSAGSKEKVDLLKTKFGFDDAF-------N 207 +G+ V+ ++ +G+ + + G V+ + S E+ + + N Sbjct: 6 QGKVSLVTGSTRGIGRAIAEKLASAGSTVIITGTSGERAKAVAEEIANKYGVKAHGVEMN 65 Query: 208 YKEESDLTAALKRCFP--NGIDIYFENVG 234 E + A + + +GIDI N G Sbjct: 66 LLSEESINKAFEEIYNLVDGIDILVNNAG 94 >1KOL-A nrPDB Length = 398 Score = 32.9 bits (73), Expect = 0.19, Method: Composition-based stats. Identities = 28/134 (20%), Positives = 45/134 (33%), Gaps = 6/134 (4%) Query: 104 VAWEEYSVITPMTHAHFKIQHTDVPLSYYTGLLGMPGM--TAYAGFYEVCSPKEGETVYV 161 EY ++ K+ D + L + + T Y G G TVYV Sbjct: 133 GGQAEYVLVPYADFNLLKLPDRDKAMEKIRDLTCLSDILPTGYHGAV-TAGVGPGSTVYV 191 Query: 162 SAASGAVGQLVGQLAKMMGCYVVGSAGSKEKVDLLKTKFGFDDAFNYKEESDLTAALKRC 221 A +G VG A+++G VV G L K + + ++ L + Sbjct: 192 -AGAGPVGLAAAASARLLGAAVV-IVGDLNPARLAHAKAQGFEIADLSLDTPLHEQIAAL 249 Query: 222 FPNG-IDIYFENVG 234 +D + VG Sbjct: 250 LGEPEVDCAVDAVG 263 >3L07-A nrPDB Length = 285 Score = 32.9 bits (73), Expect = 0.23, Method: Composition-based stats. Identities = 22/97 (22%), Positives = 36/97 (37%), Gaps = 3/97 (3%) Query: 146 GFYEVCSPKEGETVYVSAASGAVGQLVGQLAKMMGCYVVGSAGSKEKVDLLKTKFGFDDA 205 E EG V AS VG+ V QL ++ + + DL D Sbjct: 151 MLREYGIKTEGAYAVVVGASNVVGKPVSQL--LLNAKATVTTCHRFTTDLKSHTTKADIL 208 Query: 206 FNYK-EESDLTAALKRCFPNGIDIYFENVGGKMLDAV 241 + + +TA + + ID+ +V GK++ V Sbjct: 209 IVAVGKPNFITADMVKEGAVVIDVGINHVDGKIVGDV 245 >1HXH-A nrPDB Length = 253 Score = 32.5 bits (72), Expect = 0.26, Method: Composition-based stats. Identities = 11/47 (23%), Positives = 19/47 (40%) Query: 155 EGETVYVSAASGAVGQLVGQLAKMMGCYVVGSAGSKEKVDLLKTKFG 201 +G+ V+ + VG V +L G V S ++ L + G Sbjct: 5 QGKVALVTGGASGVGLEVVKLLLGEGAKVAFSDINEAAGQQLAAELG 51 >4JLW-A nrPDB Length = 399 Score = 32.5 bits (72), Expect = 0.27, Method: Composition-based stats. Identities = 27/134 (20%), Positives = 45/134 (33%), Gaps = 4/134 (2%) Query: 103 IVAWEEYSVITPMTHAHFKIQHTDVPLSYYTGLLGMPGM--TAYAGFYEVCSPKEGETVY 160 + EY ++ K+ + + + L + + T Y G G TVY Sbjct: 133 VGGQAEYVLVPYADFNLLKLPNREAAMEKIRDLTCLSDILPTGYHGAV-TAGVGPGSTVY 191 Query: 161 VSAASGAVGQLVGQLAKMMGCYVVGSAGSKEKVDLLKTKFGFDDAFNYKEESDLTAALKR 220 + A +G VG A+++G VV K GF+ A K+ Sbjct: 192 I-AGAGPVGLAAAASARLLGAAVVIVGDVNPTRLAHAKKQGFEIADLSKDTPLHEQIAAL 250 Query: 221 CFPNGIDIYFENVG 234 +D + VG Sbjct: 251 LGEPEVDCAVDAVG 264 >3UF0-A nrPDB Length = 273 Score = 32.5 bits (72), Expect = 0.27, Method: Composition-based stats. Identities = 18/86 (20%), Positives = 30/86 (34%), Gaps = 6/86 (6%) Query: 155 EGETVYVSAASGAVGQLVGQLAKMMGCYVVG---SAGSKEKVDLLKTKFGFDDAFN---Y 208 G T V+ A +G+ + G +V+ + G KE D + G +A Sbjct: 30 AGRTAVVTGAGSGIGRAIAHGYARAGAHVLAWGRTDGVKEVADEIADGGGSAEAVVADLA 89 Query: 209 KEESDLTAALKRCFPNGIDIYFENVG 234 E A + +D+ N G Sbjct: 90 DLEGAANVAEELAATRRVDVLVNNAG 115 >4CQM-B nrPDB Length = 244 Score = 32.5 bits (72), Expect = 0.29, Method: Composition-based stats. Identities = 13/63 (20%), Positives = 22/63 (34%), Gaps = 3/63 (4%) Query: 161 VSAASGAVGQLVGQLAKMMGCYVVGSAGSKEKVDLLKTKFGFDD---AFNYKEESDLTAA 217 V S +G+ V QL G + A + E G D + + +E D+ Sbjct: 14 VFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHDVQNT 73 Query: 218 LKR 220 + Sbjct: 74 FEE 76 >1OOE-A nrPDB Length = 236 Score = 32.5 bits (72), Expect = 0.29, Method: Composition-based stats. Identities = 16/77 (20%), Positives = 26/77 (33%) Query: 159 VYVSAASGAVGQLVGQLAKMMGCYVVGSAGSKEKVDLLKTKFGFDDAFNYKEESDLTAAL 218 V V GA+G + + K G V+ S + + +E+S L Sbjct: 6 VIVYGGKGALGSAILEFFKKNGYTVLNIDLSANDQADSNILVDGNKNWTEQEQSILEQTA 65 Query: 219 KRCFPNGIDIYFENVGG 235 + +D F GG Sbjct: 66 SSLQGSQVDGVFCVAGG 82 >3LYL-A nrPDB Length = 247 Score = 32.5 bits (72), Expect = 0.29, Method: Composition-based stats. Identities = 27/141 (19%), Positives = 46/141 (32%), Gaps = 8/141 (5%) Query: 160 YVSAASGAVGQLVGQLAKMMGCYVVGSAGSKEKVDLLKTKF---GFDD---AFNYKEESD 213 V+ AS +G V G VVG+A S+ + + GF N + Sbjct: 9 LVTGASRGIGFEVAHALASKGATVVGTATSQASAEKFENSMKEKGFKARGLVLNISDIES 68 Query: 214 LTAALKRCFPN--GIDIYFENVGGKMLDAVLVNMNMHGRIAVCGMISQYNLENQEGVHNL 271 + IDI N G + ++ + + +S ++E V + Sbjct: 69 IQNFFAEIKAENLAIDILVNNAGITRDNLMMRMSEDEWQSVINTNLSSIFRMSKECVRGM 128 Query: 272 SNIIYKRIRIQGFVVSDFYDK 292 + RI G VV + Sbjct: 129 MKKRWGRIISIGSVVGSAGNP 149 >4FHN-X nrPDB Length = 450 Score = 32.5 bits (72), Expect = 0.30, Method: Composition-based stats. Identities = 27/124 (21%), Positives = 39/124 (31%), Gaps = 16/124 (12%) Query: 145 AGFYEVCSPKEGETVYVSAASGAVGQLVGQLAKMMGCYVVGSAGSKEKVD----LLKTKF 200 A EG V VS SG V Q + A G V+ ++ S V K K Sbjct: 224 AMLKRHGMGFEGMRVSVSG-SGNVAQYAIEKAMEFGARVITASDSSGTVVDESGFTKEKL 282 Query: 201 GFD---------DAFNYKEESDLTAAL-KRCFPNGIDIYFENVGGKMLDAVLV-NMNMHG 249 +Y +E L ++ + +DI LD + +G Sbjct: 283 ARLIEIKSSRDGRVADYAKEFGLVYLEGQQPWSVPVDIALPCATQNELDVDAAHQLIANG 342 Query: 250 RIAV 253 AV Sbjct: 343 VKAV 346 >3ZV3-A nrPDB Length = 281 Score = 32.1 bits (71), Expect = 0.33, Method: Composition-based stats. Identities = 27/165 (16%), Positives = 52/165 (31%), Gaps = 13/165 (7%) Query: 156 GETVYVSAASGAVGQLVGQLAKMMGCYVVGSAGSKEKVDLLKTKFGFDD---AFNYKEES 212 GE ++ + +G+ + G V S E++ L+ G + + + Sbjct: 5 GEVALITGGASGLGRALVDRFVAEGARVAVLDKSAERLRELEVAHGGNAVGVVGDVRSLQ 64 Query: 213 DLTAALKRCFP--NGIDIYFENVGGKMLDAVLVNMNMHGRIAVCGMISQYNLEN------ 264 D A +RC ID N G L ++ A I N++ Sbjct: 65 DQKRAAERCLAAFGKIDTLIPNAGIWDYSTALADLPEDKIDAAFDDIFHVNVKGYIHAVK 124 Query: 265 --QEGVHNLSNIIYKRIRIQGFVVSDFYDKYSKFLEFVLPHIREG 307 + + + I GF + Y+ V+ +R+ Sbjct: 125 ACLPALVSSRGSVVFTISNAGFYPNGGGPLYTATKHAVVGLVRQM 169 >1CYD-A nrPDB Length = 244 Score = 32.1 bits (71), Expect = 0.33, Method: Composition-based stats. Identities = 10/80 (12%), Positives = 20/80 (25%) Query: 155 EGETVYVSAASGAVGQLVGQLAKMMGCYVVGSAGSKEKVDLLKTKFGFDDAFNYKEESDL 214 G V+ A +G+ + G VV + + L + + Sbjct: 6 SGLRALVTGAGKGIGRDTVKALHASGAKVVAVTRTNSDLVSLAKECPGIEPVCVDLGDWD 65 Query: 215 TAALKRCFPNGIDIYFENVG 234 +D+ N Sbjct: 66 ATEKALGGIGPVDLLVNNAA 85 >2B4Q-A nrPDB Length = 276 Score = 32.1 bits (71), Expect = 0.36, Method: Composition-based stats. Identities = 17/101 (16%), Positives = 28/101 (27%), Gaps = 6/101 (5%) Query: 155 EGETVYVSAASGAVGQLVGQLAKMMGCYVVGSAGSKEKVDLLKTKFGF-----DDAFNYK 209 G V+ S +GQ++ Q G V A E T+ + Sbjct: 28 AGRIALVTGGSRGIGQMIAQGLLEAGARVFICARDAEACADTATRLSAYGDCQAIPADLS 87 Query: 210 EESDLTAALKRCFPNGIDI-YFENVGGKMLDAVLVNMNMHG 249 E+ + + N G A L + + G Sbjct: 88 SEAGARRLAQALGELSARLDILVNNAGTSWGAALESYPVSG 128 >1E3W-A nrPDB Length = 261 Score = 32.1 bits (71), Expect = 0.39, Method: Composition-based stats. Identities = 20/120 (16%), Positives = 37/120 (30%), Gaps = 12/120 (10%) Query: 155 EGETVYVSAASGAVGQ-----LVGQLAKMMGCYVVGSAGSKEKVDLLKTKFGFDDAFNYK 209 +G ++ + +G LVGQ A + V S G E L + Sbjct: 9 KGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVTSE 68 Query: 210 EESDLTAALKRCFPNGIDIYFENVGGKMLDAV-------LVNMNMHGRIAVCGMISQYNL 262 +E L + ID+ G + + + R+ +I +N+ Sbjct: 69 KEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTFNV 128 >2ZAT-A nrPDB Length = 260 Score = 31.7 bits (70), Expect = 0.42, Method: Composition-based stats. Identities = 18/99 (18%), Positives = 33/99 (33%), Gaps = 8/99 (8%) Query: 148 YEVCSPKEGETVYVSAASGAVGQLVGQLAKMMGCYVVGSAGSKEKVDLLKTKFGFDD--- 204 E P E + V+A++ +G + + G +VV S+ +E VD + Sbjct: 6 VERRKPLENKVALVTASTDGIGLAIARRLAQDGAHVVVSSRKQENVDRTVATLQGEGLSV 65 Query: 205 ---AFNYKEESDLTAALKRCFP--NGIDIYFENVGGKML 238 + + D + G+DI N Sbjct: 66 TGTVCHVGKAEDRERLVAMAVNLHGGVDILVSNAAVNPF 104 >3C3P-A nrPDB Length = 210 Score = 31.7 bits (70), Expect = 0.43, Method: Composition-based stats. Identities = 15/124 (12%), Positives = 36/124 (29%), Gaps = 4/124 (3%) Query: 145 AGFYEVCSPKEGETVYVSAASGAVGQLVGQLAKMMGCYVVGSAGSKEKVDLLKTKFGFDD 204 Y + K+ + V V A + VV ++ V+ + + Sbjct: 46 RLLYLLARIKQPQLVVVPGDGLGCASWWFARAISISSRVVMIDPDRDNVEHARRMLHDNG 105 Query: 205 AFNYKEESDLTAALKRCFPNGIDIYF-EN---VGGKMLDAVLVNMNMHGRIAVCGMISQY 260 + E IDI F + G +L+ + + + + + + Sbjct: 106 LIDRVELQVGDPLGIAAGQRDIDILFMDCDVFNGADVLERMNRCLAKNALLIAVNALRRG 165 Query: 261 NLEN 264 ++ Sbjct: 166 SVAE 169 >3RWB-A nrPDB Length = 247 Score = 31.7 bits (70), Expect = 0.46, Method: Composition-based stats. Identities = 18/89 (20%), Positives = 30/89 (33%), Gaps = 5/89 (5%) Query: 155 EGETVYVSAASGAVGQLVGQLAKMMGCYVVGSAGSKEKVDLLKTKFGFDD---AFNYKEE 211 G+T V+ A+ +G+ + G V+ S + E G A + + Sbjct: 5 AGKTALVTGAAQGIGKAIAARLAADGATVIVSDINAEGAKAAAASIGKKARAIAADISDP 64 Query: 212 SDLTA--ALKRCFPNGIDIYFENVGGKML 238 + A A + GIDI N Sbjct: 65 GSVKALFAEIQALTGGIDILVNNASIVPF 93 >4IIN-A nrPDB Length = 271 Score = 31.7 bits (70), Expect = 0.46, Method: Composition-based stats. Identities = 20/88 (22%), Positives = 33/88 (37%), Gaps = 9/88 (10%) Query: 156 GETVYVSAASGAVGQLVGQLAKMMGCYV-VGSAGSKEKVDLLKTKF------GFDDAFNY 208 G+ V ++ AS +G + + MG V + + E D LK + F+ Sbjct: 29 GKNVLITGASKGIGAEIAKTLASMGLKVWINYRSNAEVADALKNELEEKGYKAAVIKFDA 88 Query: 209 KEESDLTAALKRC--FPNGIDIYFENVG 234 ESD A++ G+ N G Sbjct: 89 ASESDFIEAIQTIVQSDGGLSYLVNNAG 116 >2YFH-A nrPDB Length = 448 Score = 31.3 bits (69), Expect = 0.55, Method: Composition-based stats. Identities = 28/125 (22%), Positives = 42/125 (33%), Gaps = 18/125 (14%) Query: 145 AGFYEVCSPKEGETVYVSAASGAVGQLVGQLAKMMGCYVVGSAGS-----------KEKV 193 A EG V VS SG V Q + A G V+ ++ S KEK+ Sbjct: 220 AMLKRHGMGFEGMRVSVSG-SGNVAQYAIEKAMEFGARVITASDSSGTVVDESGFTKEKL 278 Query: 194 DLLKTKFGFD---DAFNYKEESDLTAAL-KRCFPNGIDIYFENVGGKMLDAVLV-NMNMH 248 L + +Y +E L ++ + +DI LD + + Sbjct: 279 ARL-IEIKASRDGRVADYAKEFGLVYLEGQQPWSLPVDIALPCATQNELDVDAAHQLIAN 337 Query: 249 GRIAV 253 G AV Sbjct: 338 GVKAV 342 >5ILO-A nrPDB Length = 271 Score = 31.3 bits (69), Expect = 0.65, Method: Composition-based stats. Identities = 18/89 (20%), Positives = 28/89 (31%), Gaps = 11/89 (12%) Query: 156 GETVYVSAASGAVG-QLVGQLAKMMGCYVVGSAGSKEKVDLLKTKFG---------FDDA 205 G+ V+ +G +G Q+ QL V + +K + D Sbjct: 15 GKNAVVTGGAGGIGLQVSKQLLAAGAAKVAIIDLQDNLEEFVKLRAAHPTQSVMIIKMDV 74 Query: 206 FNYKEESDLTAALKRCFPNGIDIYFENVG 234 N K + + F N IDI G Sbjct: 75 ANKKGVEATYEEIAKTFGN-IDIVVNVAG 102 >3X43-A nrPDB Length = 332 Score = 31.3 bits (69), Expect = 0.69, Method: Composition-based stats. Identities = 14/48 (29%), Positives = 19/48 (39%), Gaps = 1/48 (2%) Query: 150 VCSPKEGETVYVSAASGAVGQLVGQLAKMMGCYVVGSAGSKEKVDLLK 197 K G+T+ V SG VG + +A G V G V+ K Sbjct: 57 KGLLKPGDTI-VECTSGNVGIALAMVAAARGYRFVAVMGDTYSVERRK 103 >3GDF-A nrPDB Length = 267 Score = 31.0 bits (68), Expect = 0.78, Method: Composition-based stats. Identities = 28/150 (18%), Positives = 48/150 (32%), Gaps = 10/150 (6%) Query: 138 MPG--MTAYAGFYEVCSPKEGETVYVSAASG--AVGQLVGQLAKMMGCYVVGS-----AG 188 MPG T + + S K G+ V V+ ASG +G + MG V + G Sbjct: 1 MPGQQATKHESLLDQLSLK-GKVVVVTGASGPKGMGIEAARGCAEMGAAVAITYASRAQG 59 Query: 189 SKEKVDLLKTKFGFDDAFNYKEESDLTAALKRCFPNGIDIYFENVGGKMLDAVLVNMNMH 248 ++E V L+ +G + + K D + A + + Sbjct: 60 AEENVKELEKTYGIKAKAYKCQVDSYESCEKLVKDVVADFGQIDAFIANAGATADSGILD 119 Query: 249 GRIAVCGMISQYNLENQEGVHNLSNIIYKR 278 G + + Q +L +K Sbjct: 120 GSVEAWNHVVQVDLNGTFHCAKAVGHHFKE 149 >2R6H-A nrPDB Length = 290 Score = 31.0 bits (68), Expect = 0.80, Method: Composition-based stats. Identities = 22/97 (22%), Positives = 30/97 (30%), Gaps = 18/97 (18%) Query: 63 PSTAALAQAYTPGQPIQGYGVSRIIESGHPDYKKGDLLWGIVAWEEYSVITPMTHAHFKI 122 P A + G G S I K GD + + + F I Sbjct: 110 PPFDRAANKWKAG-IKPGISSSYIF-----SLKPGDKVMMSGPYGD-----------FHI 152 Query: 123 QHTDVPLSYYTGLLGMPGMTAYAGFYEVCSPKEGETV 159 Q TD + Y G GM + A + + K G V Sbjct: 153 QDTDAEMLYIGGGAGMAPLRAQI-LHLFRTLKTGRKV 188 >6EOT-A nrPDB Length = 898 Score = 31.0 bits (68), Expect = 0.82, Method: Composition-based stats. Identities = 28/195 (14%), Positives = 48/195 (24%), Gaps = 23/195 (11%) Query: 123 QHTDVPLSYYTGLLGMPGMTAYAGFYEVCSPKEGETV-------------YVSAASGAVG 169 D G T Y Y+ + G+ V+ V Sbjct: 626 PLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVK 685 Query: 170 QLVGQLAKMMGCYVVGSAGSKEKVDLLKTKFGFDDAFNYKEESDLTAALKRCFPNGIDIY 229 +G VV LK + F E D L+ D Sbjct: 686 YFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASR-YDFI 744 Query: 230 -FENVGGKMLD----AVLVNMNMHG---RIAVCGMISQYNLENQEGVHNLSNIIYKRIRI 281 + VG L+ + R+A+ G + + + + + Sbjct: 745 DLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIF-YDTGYTERYMGHPDQNE 803 Query: 282 QGFVVSDFYDKYSKF 296 QG+ + + KF Sbjct: 804 QGYYLGSVAMQAEKF 818 >6DLL-A nrPDB Length = 398 Score = 31.0 bits (68), Expect = 0.82, Method: Composition-based stats. Identities = 23/123 (18%), Positives = 43/123 (34%), Gaps = 7/123 (5%) Query: 164 ASGAVGQLVGQLAKMMGCYVVGSAGSKEKVDLLKTKFGFDD--AFNYKEESDLTAALKRC 221 +G G L+GQL G + + L + + G + + E+ + + R Sbjct: 12 GAGPSGLLLGQLLHKAGIDNIIVERQTAEYVLGRIRAGVLEQGTVDLLREAGVAERMDRE 71 Query: 222 F--PNGIDIYFENVGGKMLDAVLVNMNMHGRIAVCGMISQYNLENQEGVHNLSNIIYKRI 279 G+++ VGG+ L + + V G Q + + IIY Sbjct: 72 GLVHEGVELL---VGGRRQRLDLKALTGGKTVMVYGQTEVTRDLMQAREASGAPIIYSAA 128 Query: 280 RIQ 282 +Q Sbjct: 129 NVQ 131 >5TQV-A nrPDB Length = 233 Score = 31.0 bits (68), Expect = 0.87, Method: Composition-based stats. Identities = 13/78 (16%), Positives = 29/78 (37%) Query: 157 ETVYVSAASGAVGQLVGQLAKMMGCYVVGSAGSKEKVDLLKTKFGFDDAFNYKEESDLTA 216 +TV + AS +G+ + + G V+ +A + L+ A + + + A Sbjct: 10 KTVLIVGASRGLGREFVRQYQRDGWNVIATARDDASLAALRALGAHAHALDITQPEQIAA 69 Query: 217 ALKRCFPNGIDIYFENVG 234 + +D+ G Sbjct: 70 LGWKLDGERLDVAVVVSG 87 >5JJC-A nrPDB Length = 342 Score = 31.0 bits (68), Expect = 0.91, Method: Composition-based stats. Identities = 29/147 (19%), Positives = 47/147 (31%), Gaps = 32/147 (21%) Query: 153 PKEGETVYVSAASGAVGQLVGQLAKMMGCY---VVGSAGSKEKVDLLKTKFGFDD----A 205 + G V V +G G + +AK +G V+ S+EK D L+ G + A Sbjct: 59 LRPG-GVIVEGTAGNTGIGLTMVAKALGYRTAIVIPETASQEKKDALRL-LGAELIEVPA 116 Query: 206 FNYKEESD-------LTAALKRCFPNGI------------DIYFENVGGKMLDAVLVNMN 246 Y+ ++ L L + PNG + E ++ + Sbjct: 117 APYRNPNNAVRLSGRLAEQLAKTEPNGAIWANQFDNTVNRQAHIETTAQEIWRDTSDQI- 175 Query: 247 MHGRIAVCGMISQYNLENQEGVHNLSN 273 G +A G S L N Sbjct: 176 -DGFVAAVG--SGGTLAGTAIGLKERN 199 >2CDH-G nrPDB Length = 244 Score = 30.6 bits (67), Expect = 0.95, Method: Composition-based stats. Identities = 19/85 (22%), Positives = 33/85 (38%), Gaps = 9/85 (10%) Query: 159 VYVSAASGAVGQLVGQLAKMMGCYV-VGSAGSKEKVDLLKTKFGFDDAF------NYKEE 211 V V+ AS +G+ + GC V V A S + + + + + +E Sbjct: 4 VVVTGASRGIGKAIALSLGKAGCKVLVNYARSAKAAEEVSKQIEAYGGQAITFGGDVSKE 63 Query: 212 SDLTAALKRCFP--NGIDIYFENVG 234 +D+ A +K ID+ N G Sbjct: 64 ADVEAMMKTAIDAWGTIDVVVNNAG 88 >5ITV-A nrPDB Length = 255 Score = 30.6 bits (67), Expect = 0.97, Method: Composition-based stats. Identities = 13/87 (14%), Positives = 32/87 (36%), Gaps = 6/87 (6%) Query: 157 ETVYVSAASGAVGQLVGQ--LAKMMGCYVVGSAGSKEKVDLLKTKFGFDDAF--NYKEES 212 +TV ++ + +G Q L + V ++ + + K + +E+ Sbjct: 8 KTVLITGGASGIGYAAVQAFLGQQANVVVADIDEAQGEAMVRKENNDRLHFVQTDITDEA 67 Query: 213 DLTAALKRC--FPNGIDIYFENVGGKM 237 A++ G+D+ N G ++ Sbjct: 68 ACQHAVESAVHTFGGLDVLINNAGIEI 94 >1YS4-A nrPDB Length = 354 Score = 30.6 bits (67), Expect = 1.1, Method: Composition-based stats. Identities = 19/119 (15%), Positives = 37/119 (31%), Gaps = 7/119 (5%) Query: 159 VYVSAASGAVGQLVGQLAKMMGCYVVGSAGSKEKVDLLKTKFGFDDAFNYKEESDLTAAL 218 V V A+G+VGQ QL + + + + E+ K K + ++ + Sbjct: 11 VGVLGATGSVGQRFVQLLADHPMFELTALAASERSAGKKYKDACYWFQDRDIPENIKDMV 70 Query: 219 KRCFP------NGIDIYFENVGGKMLDAVLVNMNMHGRIAVCGMISQYNLENQEGVHNL 271 +DI F + + G++ S Y +E + Sbjct: 71 VIPTDPKHEEFEDVDIVFSALPSDLAKKFEPEFAKEGKLI-FSNASAYRMEEDVPLVIP 128 >4DBZ-A nrPDB Length = 281 Score = 30.2 bits (66), Expect = 1.2, Method: Composition-based stats. Identities = 14/91 (15%), Positives = 32/91 (35%), Gaps = 8/91 (8%) Query: 154 KEGETVYVSAASGAVGQLVGQLAKMMGCYVVGSAGSKEKV-----DLLKTKFGFD-DAFN 207 ++ E V+ A+ +G + + G V A +E + +L + D + Sbjct: 24 QDSEVALVTGATSGIGLEIARRLGKEGLRVFVCARGEEGLRTTLKELREAGVEADGRTCD 83 Query: 208 YKEESDLTAALKRCFPN--GIDIYFENVGGK 236 + ++ A + +D+ N G Sbjct: 84 VRSVPEIEALVAAVVERYGPVDVLVNNAGRP 114 >1NPY-A nrPDB Length = 271 Score = 30.2 bits (66), Expect = 1.2, Method: Composition-based stats. Identities = 20/133 (15%), Positives = 36/133 (27%), Gaps = 19/133 (14%) Query: 143 AYAGFYEVCSPKEGETVYVSAASGAVGQLVGQLAKMMGCYVVGSAGSKEKV-DLLKTKFG 201 A E + V V SG + + V K G + K L +G Sbjct: 106 AIVKLIEKYHLNKNAKVIVHG-SGGMAKAVVAAFKNSGFEKLKIYARNVKTGQYLAALYG 164 Query: 202 -----------FDDAFNYK------EESDLTAALKRCFPNGIDIYFENVGGKMLDAVLVN 244 D N + ++ A + F + + F+ V + + Sbjct: 165 YAYINSLENQQADILVNVTSIGMKGGKEEMDLAFPKAFIDNASVAFDVVAMPVETPFIRY 224 Query: 245 MNMHGRIAVCGMI 257 G+ + G Sbjct: 225 AQARGKQTISGAA 237 >4AVY-A nrPDB Length = 242 Score = 30.2 bits (66), Expect = 1.4, Method: Composition-based stats. Identities = 10/32 (31%), Positives = 15/32 (46%), Gaps = 2/32 (6%) Query: 155 EGETVYVSAASGAVGQL-VGQLAKMMGCYVVG 185 G+ V V+ S +G Q A+ +G VV Sbjct: 10 AGQQVLVTGGSSGIGAAIAMQFAE-LGAEVVA 40 >5IJZ-A nrPDB Length = 447 Score = 30.2 bits (66), Expect = 1.4, Method: Composition-based stats. Identities = 19/94 (20%), Positives = 36/94 (38%), Gaps = 5/94 (5%) Query: 146 GFYEVCSPKEGETVYVSAASGAVGQLVGQLAKMMGCYVVGSAGSKEKVDLLKTKFGFDDA 205 G+ + VS SG V + A+ +G V+G + S + T G D A Sbjct: 223 MIKAKGESISGQKIIVSG-SGNVATYAIEKAQELGATVIGFSDSSG---WVHTPNGVDVA 278 Query: 206 FNYKEESDLTAALKRCFPNGIDIYFENVGGKMLD 239 +E ++ A + + ++ + G + D Sbjct: 279 -KLREIKEVRRARVSVYADEVEGATYHTDGSIWD 311 >2C07-A nrPDB Length = 285 Score = 29.8 bits (65), Expect = 1.7, Method: Composition-based stats. Identities = 12/98 (12%), Positives = 37/98 (37%), Gaps = 8/98 (8%) Query: 155 EGETVYVSAASGAVGQLVGQLAKMMGCYVVGSAGSKEKVDLLKTKFG------FDDAFNY 208 E + V+ A +G+ + ++ +V+ + +++ D + + A + Sbjct: 43 ENKVALVTGAGRGIGREIAKMLAKSVSHVICISRTQKSCDSVVDEIKSFGYESSGYAGDV 102 Query: 209 KEESDLTAALKRCFP--NGIDIYFENVGGKMLDAVLVN 244 ++ +++ + + +DI N G + L Sbjct: 103 SKKEEISEVINKILTEHKNVDILVNNAGITRDNLFLRM 140 >3D2A-A nrPDB Length = 181 Score = 29.8 bits (65), Expect = 1.8, Method: Composition-based stats. Identities = 14/104 (13%), Positives = 33/104 (31%), Gaps = 5/104 (4%) Query: 213 DLTAALKRCFPNGIDIYFENVGGKMLDAVLVNMNMHGRIAVCGMISQYNL----ENQEGV 268 + L +DI ++GG + N++ ++A + N + G Sbjct: 58 FVQKVLDETGAKKVDIVAHSMGGANTLYYIKNLDGGNKVANVVTLGGANRLTTGKAPPGT 117 Query: 269 HNLSNIIYKRI-RIQGFVVSDFYDKYSKFLEFVLPHIREGKITY 311 I+Y I +V ++ + + + + Y Sbjct: 118 DPNQKILYTSIYSSDDMIVMNYLSRLDGARNVQIHGVGHMGLLY 161 >3W8F-A nrPDB Length = 260 Score = 29.8 bits (65), Expect = 1.8, Method: Composition-based stats. Identities = 9/47 (19%), Positives = 21/47 (44%), Gaps = 1/47 (2%) Query: 155 EGETVYVSAASGAVGQL-VGQLAKMMGCYVVGSAGSKEKVDLLKTKF 200 +G+ V+ ++ +G +LAK V+ G E ++ ++ Sbjct: 3 KGKKAVVTGSTSGIGLAMATELAKAGADVVINGFGQPEDIERERSTL 49 >4ZZA-A nrPDB Length = 396 Score = 29.8 bits (65), Expect = 1.9, Method: Composition-based stats. Identities = 31/181 (17%), Positives = 57/181 (31%), Gaps = 17/181 (9%) Query: 55 RIRMGKPDPSTAALAQAYTPGQPIQGYGVSRIIESGHPDYKKGDLLWGIVAWEEYSVITP 114 + R +P A LA A+T P+ + + ES + K GD + + W E Sbjct: 158 KFRDAGINPVQATLADAWTTQAPLASLAGTLVPESEYAALKSGDTTFKQI-WTE---PIE 213 Query: 115 MTHAHFKIQHTDVPLSYYTGLLGMPGMTA------YAGFYEVCSPKEGETVYVSAASGAV 168 FK ++ ++Y G TA ++ + + A A Sbjct: 214 KEIELFKYADSEKGVTYQQGTQNFAKGTAAIIPLGTYAIPQITMVNK-DIDLGFAQMPAT 272 Query: 169 GQLVGQLAKMMGCYVVGSAGSKEKVD-----LLKTKFGFDDAFNYKEESDLTAALKRCFP 223 Q+ G V+ + G+ + ++ NY + LK + Sbjct: 273 NDASKQILTA-GDDVILTMGANSRHKEQSMRFIRFLMSKKQLENYADAQSAITPLKETYF 331 Query: 224 N 224 Sbjct: 332 G 332 >1O5I-A nrPDB Length = 249 Score = 29.8 bits (65), Expect = 1.9, Method: Composition-based stats. Identities = 18/78 (23%), Positives = 31/78 (39%), Gaps = 7/78 (8%) Query: 159 VYVSAASGAVGQLVGQLAKMMGCYVVGSAGSKEKVDLLKTKFGFDDAFNYKEESDLTAAL 218 V V AAS +G+ V + G V A ++E + ++ + +++ D L Sbjct: 22 VLVLAASRGIGRAVADVLSQEGAEVTICARNEELLKRSGHRY---VVCDLRKDLD----L 74 Query: 219 KRCFPNGIDIYFENVGGK 236 +DI N GG Sbjct: 75 LFEKVKEVDILVLNAGGP 92 >4R1T-A nrPDB Length = 337 Score = 29.4 bits (64), Expect = 2.1, Method: Composition-based stats. Identities = 17/82 (20%), Positives = 27/82 (32%), Gaps = 2/82 (2%) Query: 155 EGETVYVSAASGAVGQLVGQLAKMMGCYVVGSAG--SKEKVDLLKTKFGFDDAFNYKEES 212 G+ V V+ A G + + ++ G V G+ K L+ G + + Sbjct: 9 SGQVVCVTGAGGFIASWLVKILLEKGYTVRGTVRNPDDPKNGHLRELEGAKERLTLCKAD 68 Query: 213 DLTAALKRCFPNGIDIYFENVG 234 L R NG D F Sbjct: 69 LLDYQSLREAINGCDGVFHTAS 90 >6DTT-A nrPDB Length = 383 Score = 29.4 bits (64), Expect = 2.4, Method: Composition-based stats. Identities = 20/108 (18%), Positives = 37/108 (34%), Gaps = 4/108 (3%) Query: 215 TAALKRCFPNGIDIYFENVG--GKMLDAVLVNMNMHGRIAVCGMISQYNLENQEGVHNLS 272 +KR G+ +N G M L M ++G A+ + L Sbjct: 193 AKLIKRMIDEGVLTPGDNYGTMDSMFKEGLAAMIINGLWAIKSYKDAGINYGVAPIPELE 252 Query: 273 NIIYKRI--RIQGFVVSDFYDKYSKFLEFVLPHIREGKITYVEDVADG 318 + + +QGF+++ +EF+ I + Y +AD Sbjct: 253 PGVPAKPFVGVQGFMINAKSPNKVIAMEFLTNFIARKETMYKIYLADP 300 >5TC4-A nrPDB Length = 316 Score = 29.4 bits (64), Expect = 2.4, Method: Composition-based stats. Identities = 21/108 (19%), Positives = 31/108 (28%), Gaps = 9/108 (8%) Query: 135 LLGMPGMTAYAGFYEVCSPKEGETVYVSAASGAVGQLVGQLAKMMGCY--------VVGS 186 +L + P G+ V V+ S VG + L G + V S Sbjct: 138 MLPATPWGVWEIIKRTGIPTLGKNVVVAGRSKNVGMPIAMLLHTDGAHERPGGDATVTIS 197 Query: 187 AGSKEKVDLLKTKFGFDDAFNYKEESDLTAALK-RCFPNGIDIYFENV 233 K L K D + +L A + ID+ V Sbjct: 198 HRYTPKEQLKKHTILADIVISAAGIPNLITADMIKEGAAVIDVGINRV 245 >1DIR-A nrPDB Length = 241 Score = 29.4 bits (64), Expect = 2.4, Method: Composition-based stats. Identities = 14/81 (17%), Positives = 23/81 (28%) Query: 155 EGETVYVSAASGAVGQLVGQLAKMMGCYVVGSAGSKEKVDLLKTKFGFDDAFNYKEESDL 214 E V V GA+G Q + +V + + D+F + + Sbjct: 6 EARRVLVYGGRGALGSRCVQAFRARNWWVASIDVVENEEASASVIVKMTDSFTEQADQVT 65 Query: 215 TAALKRCFPNGIDIYFENVGG 235 K +D GG Sbjct: 66 AEVGKLLGDQKVDAILCVAGG 86 >4B4O-A nrPDB Length = 298 Score = 29.4 bits (64), Expect = 2.6, Method: Composition-based stats. Identities = 13/69 (18%), Positives = 21/69 (30%), Gaps = 6/69 (8%) Query: 157 ETVYVSAASGAVGQLVGQLAKMMGCYVVGSAGSKEKVDLLKTKFGF------DDAFNYKE 210 V V +G +G + QL G V + + + D A N Sbjct: 1 MRVLVGGGTGFIGTALTQLLNARGHEVTLVSRKPGPGRITWDELAASGLPSCDAAVNLAG 60 Query: 211 ESDLTAALK 219 E+ L + Sbjct: 61 ENILNPLRR 69 >1URG-A nrPDB Length = 402 Score = 29.0 bits (63), Expect = 2.8, Method: Composition-based stats. Identities = 28/156 (17%), Positives = 48/156 (30%), Gaps = 24/156 (15%) Query: 149 EVCSPKEGETVYVSAASGA-----VGQLVGQLAKMMGCYVVGSA-GSKEK-----VDLLK 197 E + +G+T+ V + V Q+ Q AK G V+ S K + Sbjct: 22 EASALPKGQTITVWSWQTGPELQDVKQIAAQWAKAHGDKVIVVDQSSNPKGFQFYATAAR 81 Query: 198 TKFGFDDAFNYKEES---DLTAALKRCFPNGIDIYFENVGGKMLDAVLVNMNMHGR---- 250 T G D F ++ L P+G+ G + + ++G Sbjct: 82 TGKGPDVVFGMPHDNNGVFAEEGLMAPVPSGV---LNT--GLYAPNTIDAIKVNGTMYSV 136 Query: 251 -IAVCGMISQYNLENQEGVHNLSNIIYKRIRIQGFV 285 ++V YN + K GF+ Sbjct: 137 PVSVQVAAIYYNKKLVPQPPQTWAEFVKDANAHGFM 172 >1DOH-A nrPDB Length = 283 Score = 29.0 bits (63), Expect = 2.8, Method: Composition-based stats. Identities = 30/147 (20%), Positives = 49/147 (33%), Gaps = 15/147 (10%) Query: 155 EGETVYVSAASGAVG-QLVGQLAKMMGCYVV----GSAGSKEKVDLLKTKFGFDDAF--- 206 EG+ V+ A +G ++ +L + GC V+ S S E+V K G D A Sbjct: 28 EGKVALVTGAGRGIGREMAMELGR-RGCKVIVNYANSTESAEEVVAAIKKNGSDAACVKA 86 Query: 207 NYKEESDLTAALKRCF--PNGIDIYFENVGGKMLDAVLVNMNMH-GRIAVCGMISQYNLE 263 N D+ + +DI N G V R+ Q+ + Sbjct: 87 NVGVVEDIVRMFEEAVKIFGKLDIVCSNSGVVSFGHVKDVTPEEFDRVFTINTRGQFFVA 146 Query: 264 NQEGVHNLSNIIYKRIRIQGFVVSDFY 290 + H I R+ + G + Sbjct: 147 REAYKHLE---IGGRLILMGSITGQAK 170 >3OML-A nrPDB Length = 613 Score = 29.0 bits (63), Expect = 2.9, Method: Composition-based stats. Identities = 17/94 (18%), Positives = 27/94 (28%), Gaps = 14/94 (14%) Query: 155 EGETVYVSAASGAVGQLVGQLAKMMGCYVV-----GSAGSKEKVDLLKT-------KFGF 202 +G V+ A +G+ L G VV G+ K G Sbjct: 18 DGRVAVVTGAGAGLGREYALLFAERGAKVVVNDLGGTHSGDGASQRAADIVVDEIRKAGG 77 Query: 203 DDAFNYKEESDLTAALKRC--FPNGIDIYFENVG 234 + +Y D ++ +DI N G Sbjct: 78 EAVADYNSVIDGAKVIETAIKAFGRVDILVNNAG 111 >1W1U-A nrPDB Length = 557 Score = 29.0 bits (63), Expect = 3.1, Method: Composition-based stats. Identities = 18/103 (17%), Positives = 32/103 (31%), Gaps = 14/103 (13%) Query: 137 GMPGMTAYAGFYEVCSPKEGETVYVSAASGAVGQLVGQLAKMMGCYVVGSAGSKEKVDLL 196 G ++ + + + G T G VG Q + M V+ G+ E + + Sbjct: 463 GSDAVSDWPLLNALLNTAGGATWVSLHHGGGVGMGFSQHSGM----VIVCDGTDEAAERI 518 Query: 197 KTKFGFDDAFNYKEESDLTAALKRCFPNGIDIYFENVGGKMLD 239 +D + R G DI + + LD Sbjct: 519 ARVLT----------NDPGTGVMRHADAGYDIAIDCAKEQGLD 551 >3O4R-A nrPDB Length = 261 Score = 29.0 bits (63), Expect = 3.3, Method: Composition-based stats. Identities = 15/92 (16%), Positives = 30/92 (32%), Gaps = 8/92 (8%) Query: 155 EGETVYVSAASGAVGQLVGQLAKMMGCYVVGSAGSKEKVDLLKTKFGFDD------AFNY 208 + V+A++ +G + + G +VV S+ ++ VD + + Sbjct: 14 ANKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCHV 73 Query: 209 KEESDLTAALKRCFP--NGIDIYFENVGGKML 238 + D + GIDI N Sbjct: 74 GKAEDRERLVATAVKLHGGIDILVSNAAVNPF 105 >6MDV-A nrPDB Length = 802 Score = 28.7 bits (62), Expect = 3.6, Method: Composition-based stats. Identities = 12/64 (18%), Positives = 24/64 (37%), Gaps = 2/64 (3%) Query: 153 PKEGETVYVSAASGAVGQLVGQLAK-MMGCYVVGSAGSKEKVDLLKTKFGFDDAFNYKEE 211 +GE V V +G + G V+G++G E+ + D F + + Sbjct: 615 VSDGEKV-VHHMKLNIGSGAIMMENLAKGAKVIGTSGDFEQAKKIFDGEKSDRFFTWGQT 673 Query: 212 SDLT 215 + + Sbjct: 674 NWIA 677 >4MOW-A nrPDB Length = 256 Score = 28.7 bits (62), Expect = 3.8, Method: Composition-based stats. Identities = 14/63 (22%), Positives = 23/63 (36%), Gaps = 8/63 (12%) Query: 155 EGETVYVSAASGAVGQLVGQLAKMMGCYVVGSAGSKEKVDLLKTKFGFDDAFNYKEESDL 214 G+ V+ AS +G + + G VV V+ +K G D + E+ Sbjct: 13 AGKVAIVTGASKGIGAAIAKALADEGAAVV--------VNYASSKAGADAVVSAITEAGG 64 Query: 215 TAA 217 A Sbjct: 65 RAV 67 >4R1U-A nrPDB Length = 349 Score = 28.7 bits (62), Expect = 3.9, Method: Composition-based stats. Identities = 18/91 (19%), Positives = 29/91 (31%), Gaps = 3/91 (3%) Query: 147 FYEVCSPKEGE-TVYVSAASGAVGQLVGQLAKMMGCYVVGSAGS--KEKVDLLKTKFGFD 203 S G+ TV V+ A G + + +L G V G+ + K LK G Sbjct: 17 LDNTSSVSGGDQTVCVTGAGGFIASWLVKLLLERGYTVRGTVRNPEDPKNGHLKELEGAR 76 Query: 204 DAFNYKEESDLTAALKRCFPNGIDIYFENVG 234 + + L + +G F Sbjct: 77 ERLTLHKVDLLDLQSIQSVVHGCHGVFHTAS 107 >2PTG-A nrPDB Length = 319 Score = 28.7 bits (62), Expect = 4.0, Method: Composition-based stats. Identities = 12/83 (14%), Positives = 30/83 (36%), Gaps = 7/83 (8%) Query: 156 GETVYVSAAS--GAVGQLVGQLAKMMGCYVVGSAGSKEKV-DLLKTKFGFDDAF--NYKE 210 G+T +V+ + G + +L + G V+ G+ V + K ++ Sbjct: 9 GKTAFVAGVADSNGYGWAICKLLRAAGARVL--VGTWPPVYSIFKKGLESSRFEQDSFYA 66 Query: 211 ESDLTAALKRCFPNGIDIYFENV 233 + + +D+ F+ + Sbjct: 67 QEPSSKVAAEAAEKPVDLVFDKI 89 >2JC3-A nrPDB Length = 303 Score = 28.7 bits (62), Expect = 4.1, Method: Composition-based stats. Identities = 11/43 (25%), Positives = 17/43 (39%), Gaps = 4/43 (9%) Query: 143 AYAGFYEV---CSPKEGETVYVSAASGAVGQLVGQLAKMMGCY 182 A + E K G+ V + A SG G + +A + G Sbjct: 45 ALSMIVEAEKRGEIKPGD-VLIEATSGNTGIALAMIAALKGYR 86 >2BHS-A nrPDB Length = 303 Score = 28.7 bits (62), Expect = 4.3, Method: Composition-based stats. Identities = 11/43 (25%), Positives = 17/43 (39%), Gaps = 4/43 (9%) Query: 143 AYAGFYEV---CSPKEGETVYVSAASGAVGQLVGQLAKMMGCY 182 A + E K G+ V + A SG G + +A + G Sbjct: 45 ALSMIVEAEKRGEIKPGD-VLIEATSGNTGIALAMIAALKGYR 86 >2VHY-A nrPDB Length = 377 Score = 28.3 bits (61), Expect = 5.6, Method: Composition-based stats. Identities = 23/113 (20%), Positives = 39/113 (34%), Gaps = 13/113 (11%) Query: 122 IQHTDVPLSYYTGLLGMPG-MTAYAGFYEVCSPKEGETVYVSA------------ASGAV 168 +Q D L + + G + A G Y + + G V + +G Sbjct: 120 VQTADGALPLLAPMSEVAGRLAAQVGAYHLMRTQGGRGVLMGGVPGVEPADVVVIGAGTA 179 Query: 169 GQLVGQLAKMMGCYVVGSAGSKEKVDLLKTKFGFDDAFNYKEESDLTAALKRC 221 G ++A MG V + +K+ L +F Y +L A+KR Sbjct: 180 GYNAARIANGMGATVTVLDINIDKLRQLDAEFCGRIHTRYSSAYELEGAVKRA 232 >1UZM-A nrPDB Length = 247 Score = 27.9 bits (60), Expect = 6.2, Method: Composition-based stats. Identities = 20/127 (15%), Positives = 33/127 (25%), Gaps = 25/127 (19%) Query: 158 TVYVSAASGAVGQLVGQLAKMMGCYVVGSAGSKEKVDLL-------KTKFGFDDAFNYKE 210 +V V+ + +G + Q G V + L D AF E Sbjct: 17 SVLVTGGNRGIGLAIAQRLAADGHKVAVTHRGSGAPKGLFGVEVDVTDSDAVDRAFTAVE 76 Query: 211 E-SDLTAALKRCFPNGIDIYFENVGGKMLDAVLV-----------------NMNMHGRIA 252 E L D + + + + V+ N GR+ Sbjct: 77 EHQGPVEVLVSNAGLSADAFLMRMTEEKFEKVINANLTGAFRVAQRASRSMQRNKFGRMI 136 Query: 253 VCGMISQ 259 G +S Sbjct: 137 FIGSVSG 143 >2HSD-A nrPDB Length = 253 Score = 27.9 bits (60), Expect = 7.6, Method: Composition-based stats. Identities = 17/88 (19%), Positives = 28/88 (31%), Gaps = 5/88 (5%) Query: 155 EGETVYVSAASGAVGQLVGQLAKMMGCYVVGSAGSKEKVDLLKTKFG----FDDAFNYKE 210 G+TV ++ + +G + A G VV + E+ + G + E Sbjct: 4 SGKTVIITGGARGLGAEAARQAVAAGARVVLADVLDEEGAATARELGDAARYQHLDVTIE 63 Query: 211 ESDLT-AALKRCFPNGIDIYFENVGGKM 237 E A R +D N G Sbjct: 64 EDWQRVVAYAREEFGSVDGLVNNAGIST 91 >5HPZ-A nrPDB Length = 179 Score = 27.9 bits (60), Expect = 7.7, Method: Composition-based stats. Identities = 26/130 (20%), Positives = 46/130 (35%), Gaps = 11/130 (8%) Query: 71 AYTPGQPIQGYGVSRIIESGHPDYKKGDLLWGIVAWEEYSVITPMTHAHFKIQHTDVPLS 130 Y PG P+ +G +I Y + S I P+ + K+ DV S Sbjct: 51 PYQPGLPVS-FGYEPVIAGTDYIYTSTTINIEF-----RSEIWPVCNELSKLWAVDVSSS 104 Query: 131 YY-TGLLGMPG-MTAYAGFYEVCSPKEGETVYVSAASGAVGQLVGQLAKMMGCYVVGSAG 188 + + G TA +++ T ++ +SG VG + G +G + + Sbjct: 105 AAKEPAIIIGGERTAPNSLFKIEEATGAHTYKLTTSSGTVGTIPGPW---LGAPQLIATN 161 Query: 189 SKEKVDLLKT 198 K +K Sbjct: 162 DDAKTLFVKF 171 >1X1T-A nrPDB Length = 260 Score = 27.5 bits (59), Expect = 7.8, Method: Composition-based stats. Identities = 7/53 (13%), Positives = 20/53 (37%), Gaps = 1/53 (1%) Query: 155 EGETVYVSAASGAVGQ-LVGQLAKMMGCYVVGSAGSKEKVDLLKTKFGFDDAF 206 +G+ V+ ++ +G + LA V+ G +++ ++ Sbjct: 3 KGKVAVVTGSTSGIGLGIATALAAQGADIVLNGFGDAAEIEKVRAGLAAQHGV 55 >4EJ0-A nrPDB Length = 342 Score = 27.5 bits (59), Expect = 8.3, Method: Composition-based stats. Identities = 13/93 (13%), Positives = 33/93 (35%), Gaps = 2/93 (2%) Query: 157 ETVYVSAASGAVGQLVGQLAKMMGCYVVGSAGSKEKVDLLKTKFGFDDAFNYKEESDLTA 216 T+ V+ A+G +G + + G + + + + D K + +Y ++++ Sbjct: 13 MTLIVTGAAGFIGANLVKALNERGETRIIAVDNLTRADKFKNLVDCE-IDDYLDKTEFVE 71 Query: 217 ALKRCFPNGIDIYF-ENVGGKMLDAVLVNMNMH 248 R + F E ++ M + Sbjct: 72 RFARGDFGKVRAVFHEGACSDTMETDGRYMMDN 104 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.308 0.120 0.279 Lambda K H 0.267 0.0367 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 10,939,293 Number of Sequences: 36641 Number of extensions: 417699 Number of successful extensions: 1661 Number of sequences better than 10.0: 205 Number of HSP's better than 10.0 without gapping: 150 Number of HSP's successfully gapped in prelim test: 108 Number of HSP's that attempted gapping in prelim test: 1352 Number of HSP's gapped (non-prelim): 268 length of query: 345 length of database: 10,336,785 effective HSP length: 98 effective length of query: 247 effective length of database: 6,745,967 effective search space: 1666253849 effective search space used: 1666253849 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 59 (27.5 bits)