BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q38802 (802 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 4LIX-A nrPDB 1503 0.0 3S9V-A nrPDB 506 e-143 3SDU-A nrPDB 422 e-118 3P5P-A nrPDB 393 e-109 3M02-A nrPDB 113 3e-25 2J5C-A nrPDB 113 4e-25 5JO7-A nrPDB 112 7e-25 3N0G-A nrPDB 108 6e-24 2ONH-A nrPDB 105 7e-23 4GAX-A nrPDB 105 1e-22 6O9P-A nrPDB 102 5e-22 5UV2-A nrPDB 99 1e-20 1N1Z-A nrPDB 94 2e-19 3G4D-A nrPDB 89 9e-18 5C05-A nrPDB 85 1e-16 3HW4-A nrPDB 31 2.6 4KIL-A nrPDB 30 2.9 4AWK-A nrPDB 30 3.1 4MK5-A nrPDB 30 3.3 3OQC-A nrPDB 30 3.5 2W69-A nrPDB 30 6.0 2DER-A nrPDB 29 8.8 4TXE-A nrPDB 29 9.3 >4LIX-A nrPDB Length = 727 Score = 1503 bits (3892), Expect = 0.0, Method: Compositional matrix adjust. Identities = 718/718 (100%), Positives = 718/718 (100%) Query: 85 ISVGSNSNAFKEAVKSVKTILRNLTDGEITISAYDTAWVALIDAGDKTPAFPSAVKWIAE 144 ISVGSNSNAFKEAVKSVKTILRNLTDGEITISAYDTAWVALIDAGDKTPAFPSAVKWIAE Sbjct: 2 ISVGSNSNAFKEAVKSVKTILRNLTDGEITISAYDTAWVALIDAGDKTPAFPSAVKWIAE 61 Query: 145 NQLSDGSWGDAYLFSYHDRLINTLACVVALRSWNLFPHQCNKGITFFRENIGKLEDENDE 204 NQLSDGSWGDAYLFSYHDRLINTLACVVALRSWNLFPHQCNKGITFFRENIGKLEDENDE Sbjct: 62 NQLSDGSWGDAYLFSYHDRLINTLACVVALRSWNLFPHQCNKGITFFRENIGKLEDENDE 121 Query: 205 HMPIGFEVAFPSLLEIARGINIDVPYDSPVLKDIYAKKELKLTRIPKEIMHKIPTTLLHS 264 HMPIGFEVAFPSLLEIARGINIDVPYDSPVLKDIYAKKELKLTRIPKEIMHKIPTTLLHS Sbjct: 122 HMPIGFEVAFPSLLEIARGINIDVPYDSPVLKDIYAKKELKLTRIPKEIMHKIPTTLLHS 181 Query: 265 LEGMRDLDWEKLLKLQSQDGSFLFSPSSTAFAFMQTRDSNCLEYLRNAVKRFNGGVPNVF 324 LEGMRDLDWEKLLKLQSQDGSFLFSPSSTAFAFMQTRDSNCLEYLRNAVKRFNGGVPNVF Sbjct: 182 LEGMRDLDWEKLLKLQSQDGSFLFSPSSTAFAFMQTRDSNCLEYLRNAVKRFNGGVPNVF 241 Query: 325 PVDLFEHIWIVDRLQRLGISRYFEEEIKECLDYVHRYWTDNGICWARCSHVQDIDDTAMA 384 PVDLFEHIWIVDRLQRLGISRYFEEEIKECLDYVHRYWTDNGICWARCSHVQDIDDTAMA Sbjct: 242 PVDLFEHIWIVDRLQRLGISRYFEEEIKECLDYVHRYWTDNGICWARCSHVQDIDDTAMA 301 Query: 385 FRLLRQHGYQVSADVFKNFEKEGEFFCFVGQSNQAVTGMFNLYRASQLAFPREEILKNAK 444 FRLLRQHGYQVSADVFKNFEKEGEFFCFVGQSNQAVTGMFNLYRASQLAFPREEILKNAK Sbjct: 302 FRLLRQHGYQVSADVFKNFEKEGEFFCFVGQSNQAVTGMFNLYRASQLAFPREEILKNAK 361 Query: 445 EFSYNYLLEKREREELIDKWIIMKDLPGEIGFALEIPWYASLPRVETRFYIDQYGGENDV 504 EFSYNYLLEKREREELIDKWIIMKDLPGEIGFALEIPWYASLPRVETRFYIDQYGGENDV Sbjct: 362 EFSYNYLLEKREREELIDKWIIMKDLPGEIGFALEIPWYASLPRVETRFYIDQYGGENDV 421 Query: 505 WIGKTLYRMPYVNNNGYLELAKQDYNNCQAQHQLEWDIFQKWYEENRLSEWGVRRSELLE 564 WIGKTLYRMPYVNNNGYLELAKQDYNNCQAQHQLEWDIFQKWYEENRLSEWGVRRSELLE Sbjct: 422 WIGKTLYRMPYVNNNGYLELAKQDYNNCQAQHQLEWDIFQKWYEENRLSEWGVRRSELLE 481 Query: 565 CYYLAAATIFESERSHERMVWAKSSVLVKAISSSFGESSDSRRSFSDQFHEYIANARRSD 624 CYYLAAATIFESERSHERMVWAKSSVLVKAISSSFGESSDSRRSFSDQFHEYIANARRSD Sbjct: 482 CYYLAAATIFESERSHERMVWAKSSVLVKAISSSFGESSDSRRSFSDQFHEYIANARRSD 541 Query: 625 HHFNDRNMRLDRPGSVQASRLAGVLIGTLNQMSFDLFMSHGRDVNNLLYLSWGDWMEKWK 684 HHFNDRNMRLDRPGSVQASRLAGVLIGTLNQMSFDLFMSHGRDVNNLLYLSWGDWMEKWK Sbjct: 542 HHFNDRNMRLDRPGSVQASRLAGVLIGTLNQMSFDLFMSHGRDVNNLLYLSWGDWMEKWK 601 Query: 685 LYGDEGEGELMVKMIILMKNNDLTNFFTHTHFVRLAEIINRICLPRQYLKARRNDEKEKT 744 LYGDEGEGELMVKMIILMKNNDLTNFFTHTHFVRLAEIINRICLPRQYLKARRNDEKEKT Sbjct: 602 LYGDEGEGELMVKMIILMKNNDLTNFFTHTHFVRLAEIINRICLPRQYLKARRNDEKEKT 661 Query: 745 IKSMEKEMGKMVELALSESDTFRDVSITFLDVAKAFYYFALCGDHLQTHISKVLFQKV 802 IKSMEKEMGKMVELALSESDTFRDVSITFLDVAKAFYYFALCGDHLQTHISKVLFQKV Sbjct: 662 IKSMEKEMGKMVELALSESDTFRDVSITFLDVAKAFYYFALCGDHLQTHISKVLFQKV 719 >3S9V-A nrPDB Length = 785 Score = 506 bits (1304), Expect = e-143, Method: Compositional matrix adjust. Identities = 242/507 (47%), Positives = 339/507 (66%), Gaps = 5/507 (0%) Query: 87 VGSNSNAFKEAVKSVKTILRNLTDGEITISAYDTAWVALIDA--GDKTPAFPSAVKWIAE 144 S+ + + +K + R + GE SAYDTAWVA I A G P FP V+WI + Sbjct: 26 AASDEKRIETLISEIKNMFRCMGYGETNPSAYDTAWVARIPAVDGSDNPHFPETVEWILQ 85 Query: 145 NQLSDGSWGDAYLFSYHDRLINTLACVVALRSWNLFPHQCNKGITFFRENIGKLEDENDE 204 NQL DGSWG+ + F +DR++ TLAC++ L W Q KGI FFR GK+EDE D Sbjct: 86 NQLKDGSWGEGFYFLAYDRILATLACIITLTLWRTGETQVQKGIEFFRTQAGKMEDEADS 145 Query: 205 HMPIGFEVAFPSLLEIARGINIDVPYDSPVLKDIYAKKELKLTRIPKEIMHKIPTTLLHS 264 H P GFE+ FP++L+ A+ + +D+PYD P LK I K+E KL RIP ++++ +PTTLL+S Sbjct: 146 HRPSGFEIVFPAMLKEAKILGLDLPYDLPFLKQIIEKREAKLKRIPTDVLYALPTTLLYS 205 Query: 265 LEGMRDL-DWEKLLKLQSQDGSFLFSPSSTAFAFMQTRDSNCLEYLRNAVKRFNGGVPNV 323 LEG++++ DW+K++KLQS+DGSFL SP+STA FM+T + CL++L +K+F VP Sbjct: 206 LEGLQEIVDWQKIMKLQSKDGSFLSSPASTAAVFMRTGNKKCLDFLNFVLKKFGNHVPCH 265 Query: 324 FPVDLFEHIWIVDRLQRLGISRYFEEEIKECLDYVHRYWTDNGICWARCSHVQDIDDTAM 383 +P+DLFE +W VD ++RLGI R+F+EEIKE LDYV+ +W + GI WAR + V DIDDTAM Sbjct: 266 YPLDLFERLWAVDTVERLGIDRHFKEEIKEALDYVYSHWDERGIGWARENPVPDIDDTAM 325 Query: 384 AFRLLRQHGYQVSADVFKNFEKE-GEFFCFVGQSNQAVTGMFNLYRASQLAFPREEILKN 442 R+LR HGY VS+DV K F E GEFFCF+GQ+ + VT M N+ R S ++FP E I++ Sbjct: 326 GLRILRLHGYNVSSDVLKTFRDENGEFFCFLGQTQRGVTDMLNVNRCSHVSFPGETIMEE 385 Query: 443 AKEFSYNYLLEKREREELIDKWIIMKDLPGEIGFALEIPWYASLPRVETRFYIDQYGGEN 502 AK + YL E + DKW K++ GE+ +AL+ PW+ S+PR+E R YI+ Y G + Sbjct: 386 AKLCTERYLRNALENVDAFDKWAFKKNIRGEVEYALKYPWHKSMPRLEARSYIENY-GPD 444 Query: 503 DVWIGKTLYRMPYVNNNGYLELAKQDYNNCQAQHQLEWDIFQKWYEENRLSEWGVRRSEL 562 DVW+GKT+Y MPY++N YLELAK D+N Q+ HQ E ++W++ + ++ R + Sbjct: 445 DVWLGKTVYMMPYISNEKYLELAKLDFNKVQSIHQTELQDLRRWWKSSGFTDLNFTRERV 504 Query: 563 LECYYLAAATIFESERSHERMVWAKSS 589 E Y+ A+ IFE E S R V+ K+S Sbjct: 505 TEIYFSPASFIFEPEFSKCREVYTKTS 531 >3SDU-A nrPDB Length = 817 Score = 422 bits (1086), Expect = e-118, Method: Compositional matrix adjust. Identities = 225/541 (41%), Positives = 326/541 (60%), Gaps = 15/541 (2%) Query: 98 VKSVKTILRNLTDGE----ITISAYDTAWVALIDA--GDKTPAFPSAVKWIAENQLSDGS 151 V +K +L G+ IT SAYDTAWVA + A G P FP V WI +NQL DGS Sbjct: 60 VSEIKAMLNPAITGDGESMITPSAYDTAWVARVPAIDGSARPQFPQTVDWILKNQLKDGS 119 Query: 152 WGDAYLFSYHDRLINTLACVVALRSWNLFPHQCNKGITFFRENIGKLEDENDE-HMPIGF 210 WG F DRL+ TL+CV+ L WN+ Q +GI F + N+ ++DE D+ + F Sbjct: 120 WGIQSHFLLSDRLLATLSCVLVLLKWNVGDLQVEQGIEFIKSNLELVKDETDQDSLVTDF 179 Query: 211 EVAFPSLLEIARGINIDVPYDSPVLKDIYAKKELKLTRIPKEIMHKIPTTLLHSLEGMRD 270 E+ FPSLL A+ + + +PYD P + + K++ +L ++ +E ++ +P+ LL+SLEG++D Sbjct: 180 EIIFPSLLREAQSLRLGLPYDLPYIHLLQTKRQERLAKLSREEIYAVPSPLLYSLEGIQD 239 Query: 271 L-DWEKLLKLQSQDGSFLFSPSSTAFAFMQTRDSNCLEYLRNAVKRFNGGVPNVFPVDLF 329 + +WE+++++QSQDGSFL SP+STA FM T D+ CLE+L + + +F VP ++PVDL Sbjct: 240 IVEWERIMEVQSQDGSFLSSPASTACVFMHTGDAKCLEFLNSVMIKFGNFVPCLYPVDLL 299 Query: 330 EHIWIVDRLQRLGISRYFEEEIKECLDYVHRYWTDNGICWARCSHVQDIDDTAMAFRLLR 389 E + IVD + RLGI R+FE+EIKE LDYV+R+W + GI W R + + D++ TA+ FRLLR Sbjct: 300 ERLLIVDNIVRLGIYRHFEKEIKEALDYVYRHWNERGIGWGRLNPIADLETTALGFRLLR 359 Query: 390 QHGYQVSADVFKNF-EKEGEFFCFVGQSNQAVTGMFNLYRASQLAFPREEILKNAKEFSY 448 H Y VS +F NF + G+F C GQ N+ V M NLYRASQLAFP E IL AK F+ Sbjct: 360 LHRYNVSPAIFDNFKDANGKFICSTGQFNKDVASMLNLYRASQLAFPGENILDEAKSFAT 419 Query: 449 NYLLEKREREELIDKWIIMKDLPGEIGFALEIPWYASLPRVETRFYIDQYGGENDVWIGK 508 YL E E+ E W ++L EI +AL+ W+AS+PRVE + Y Y + I K Sbjct: 420 KYLREALEKSETSSAWNNKQNLSQEIKYALKTSWHASVPRVEAKRYCQVYRPDY-ARIAK 478 Query: 509 TLYRMPYVNNNGYLELAKQDYNNCQAQHQLEWDIFQKWYEENRLSEWGVRRSELLECYYL 568 +Y++PYVNN +LEL K D+N Q+ HQ E W+ ++ L + R LE Y+L Sbjct: 479 CVYKLPYVNNEKFLELGKLDFNIIQSIHQEEMKNVTSWFRDSGLPLFTFARERPLEFYFL 538 Query: 569 AAATIFESERSHERMVWAKSSVLVKAISSSFGESSDSRRSFSDQFHEYIANARRSDHHFN 628 AA +E + + R ++ K + L + + D+ + D+ + RR D F Sbjct: 539 VAAGTYEPQYAKCRFLFTKVACLQTVLDDMY----DTYGTL-DELKLFTEAVRRWDLSFT 593 Query: 629 D 629 + Sbjct: 594 E 594 >3P5P-A nrPDB Length = 764 Score = 393 bits (1010), Expect = e-109, Method: Compositional matrix adjust. Identities = 211/502 (42%), Positives = 305/502 (60%), Gaps = 17/502 (3%) Query: 96 EAVKSVKTILRNLTDGEITISAYDTAWVALIDA----GDKTPAFPSAVKWIAENQLSDGS 151 E V +K + L DG+I+ SAYDTAWVA + G + P FP A+ W+ NQL DGS Sbjct: 12 ELVVKIKDMFNALGDGDISPSAYDTAWVARLATISSDGSEKPRFPQALNWVFNNQLQDGS 71 Query: 152 WGDAYLFSYHDRLINTLACVVALRSWNLFPHQCNKGITFFRENIGKLEDENDEHMPIGFE 211 WG FS DRL+NT V+AL W Q +G F EN+ +L +E DE P F+ Sbjct: 72 WGIESHFSLCDRLLNTTNSVIALSVWKTGHSQVQQGAEFIAENL-RLLNEEDELSP-DFQ 129 Query: 212 VAFPSLLEIARGINIDVPYDSPVLKDIYAKKELKLTRIPKEIMHKIPTTLLHSLEGMRD- 270 + FP+LL+ A+ + I++PYD P +K + +E +LT + IP +L++LEG+ + Sbjct: 130 IIFPALLQKAKALGINLPYDLPFIKYLSTTREARLTDV-SAAADNIPANMLNALEGLEEV 188 Query: 271 LDWEKLLKLQSQDGSFLFSPSSTAFAFMQTRDSNCLEYLRNAVKRFNGGVPNVFPVDLFE 330 +DW K+++ QS+DGSFL SP+STA M T D C +L N + +F G VP ++ +DL E Sbjct: 189 IDWNKIMRFQSKDGSFLSSPASTACVLMNTGDEKCFTFLNNLLDKFGGCVPCMYSIDLLE 248 Query: 331 HIWIVDRLQRLGISRYFEEEIKECLDYVHRYWTDNGICWARCSHVQDIDDTAMAFRLLRQ 390 + +VD ++ LGI R+F++EIK LDYV+R+W++ GI W R S V D++ TA+ R LR Sbjct: 249 RLSLVDNIEHLGIGRHFKQEIKGALDYVYRHWSERGIGWGRDSLVPDLNTTALGLRTLRM 308 Query: 391 HGYQVSADVFKNFEKE-GEFFCFVGQSNQAVTGMFNLYRASQLAFPREEILKNAKEFSYN 449 HGY VS+DV NF+ E G FF GQ++ + + NL+RAS LAFP E + +A++F+ Sbjct: 309 HGYNVSSDVLNNFKDENGRFFSSAGQTHVELRSVVNLFRASDLAFPDERAMDDARKFAEP 368 Query: 450 YLLEKREREELIDKWIIMKDLPGEIGFALEIPWYASLPRVETRFYIDQYGGENDVWIGKT 509 YL RE L K L EI + +E PW+ S+PR+E R YID Y +N VW KT Sbjct: 369 YL-----REALATKISTNTKLFKEIEYVVEYPWHMSIPRLEARSYIDSY-DDNYVWQRKT 422 Query: 510 LYRMPYVNNNGYLELAKQDYNNCQAQHQLEWDIFQKWYEENRLSEWGVRRSELLECYYLA 569 LYRMP ++N+ LELAK D+N Q+ HQ E + +W++E+ +++ R + E Y+ + Sbjct: 423 LYRMPSLSNSKCLELAKLDFNIVQSLHQEELKLLTRWWKESGMADINFTRHRVAEVYFSS 482 Query: 570 AATIFESERSHERMVWAKSSVL 591 A FE E S R+ + K L Sbjct: 483 AT--FEPEYSATRIAFTKIGCL 502 >3M02-A nrPDB Length = 550 Score = 113 bits (283), Expect = 3e-25, Method: Compositional matrix adjust. Identities = 78/267 (29%), Positives = 131/267 (49%), Gaps = 33/267 (12%) Query: 334 IVDRLQRLGISRYFEEEIKECLDYVHRYWTDNGICWARCSHVQDIDDTAMAFRLLRQHGY 393 ++D ++RLGIS +FE+EI + LD + + N C C+ +A+ FRLLRQHG+ Sbjct: 72 LIDTIERLGISYHFEKEIDDILDQI---YNQNSNCNDLCT-------SALQFRLLRQHGF 121 Query: 394 QVSADVFKNFEKEGEFFCFVGQSNQAVTGMFNLYRASQLAFPREEILKNAKEFSYNYLLE 453 +S ++F F+ E F S+ V G+ NLY AS + ++IL++A FS +L Sbjct: 122 NISPEIFSKFQDENGKFKESLASD--VLGLLNLYEASHVRTHADDILEDALAFSTIHLES 179 Query: 454 KREREELIDKWIIMKDLPGEIGFALEIPWYASLPRVETRFYIDQYGGENDVWIGKTLYRM 513 + L ++ ALE + +PRVETRF+I ++Y Sbjct: 180 AAPH--------LKSPLREQVTHALEQCLHKGVPRVETRFFI------------SSIYDK 219 Query: 514 PYVNNNGYLELAKQDYNNCQAQHQLEWDIFQKWYEE-NRLSEWGVRRSELLECYYLAAAT 572 NN L AK D+N Q H+ E +W+++ + ++ R ++ECY+ A Sbjct: 220 EQSKNNVLLRFAKLDFNLLQMLHKQELAQVSRWWKDLDFVTTLPYARDRVVECYFWALGV 279 Query: 573 IFESERSHERMVWAKSSVLVKAISSSF 599 FE + S R++ K+ ++ + +F Sbjct: 280 YFEPQYSQARVMLVKTISMISIVDDTF 306 >2J5C-A nrPDB Length = 569 Score = 113 bits (282), Expect = 4e-25, Method: Compositional matrix adjust. Identities = 101/320 (31%), Positives = 150/320 (46%), Gaps = 41/320 (12%) Query: 288 FSPSSTAFAFMQTRDSNCLEYLRNAVKRFNGGVPNVF-----PVDLFEHIWIVDRLQRLG 342 + P+ F+ +Q+ DS E + R G + V VD + ++D L+RLG Sbjct: 40 YQPTLWDFSTIQSFDSEYKE--EKHLMRAAGMIDQVKMMLQEEVDSIRRLELIDDLRRLG 97 Query: 343 ISRYFEEEIKECLDYVHRYWTDNGICWARCSHVQDIDDTAMAFRLLRQHGYQVSADVFKN 402 IS +FE EI E L+ +Y+T+N I +D+ TA+ FRLLRQ+ + VS +VF Sbjct: 98 ISCHFEREIVEILN--SKYYTNNEI------DERDLYSTALRFRLLRQYDFSVSQEVFDC 149 Query: 403 FEKEGEFFCFVGQSNQAVTGMFNLYRASQLAFPREEILKNAKEFSYNYLLEKREREELID 462 F K + F G+ LY AS L+ EE L+ A++F+ +L ++ L+D Sbjct: 150 F-KNAKGTDFKPSLVDDTRGLLQLYEASFLSAQGEETLRLARDFATKFL----QKRVLVD 204 Query: 463 KWIIMKDLPGEIGFALEIP--WYASLPRVETRFYIDQYGGENDVWIGKTLYRMPYVNNNG 520 K I +L I ALE+P W +P R +ID Y D+ N Sbjct: 205 KDI---NLLSSIERALELPTHWRVQMP--NARSFIDAYKRRPDM-------------NPT 246 Query: 521 YLELAKQDYNNCQAQHQLEWDIFQKWYEENRL-SEWGVRRSELLECYYLAAATIFESERS 579 LELAK D+N QAQ Q E +W+ L E R ++ECYY + + Sbjct: 247 VLELAKLDFNMVQAQFQQELKEASRWWNSTGLVHELPFVRDRIVECYYWTTGVVERRQHG 306 Query: 580 HERMVWAKSSVLVKAISSSF 599 +ER++ K + LV I F Sbjct: 307 YERIMLTKINALVTTIDDVF 326 >5JO7-A nrPDB Length = 538 Score = 112 bits (280), Expect = 7e-25, Method: Compositional matrix adjust. Identities = 76/273 (27%), Positives = 134/273 (49%), Gaps = 29/273 (10%) Query: 328 LFEHIWIVDRLQRLGISRYFEEEIKECLDYVHRYWTDNGICWARCSHVQDIDDTAMAFRL 387 L E + ++D ++RLGI+ +FE++I++ LD+++R + D++ +++ FRL Sbjct: 50 LTEKLNLIDIIERLGIAYHFEKQIEDMLDHIYR-----ADPYFEAHEYNDLNTSSVQFRL 104 Query: 388 LRQHGYQVSADVFKNFEKEGEFFCFVGQSNQAVTGMFNLYRASQLAFPREEILKNAKEFS 447 LRQHGY VS ++F F+ F +S+ + G+ NLY AS + +E+IL+ A FS Sbjct: 105 LRQHGYNVSPNIFSRFQDANGKFKESLRSD--IRGLLNLYEASHVRTHKEDILEEALVFS 162 Query: 448 YNYLLEKREREELIDKWIIMKDLPGEIGFALEIPWYASLPRVETRFYIDQYGGENDVWIG 507 +L + L ++ ALE + S+PRVE R++I Y E Sbjct: 163 VGHLESAAPH--------LKSPLSKQVTHALEQSLHKSIPRVEIRYFISIYEEEE----- 209 Query: 508 KTLYRMPYVNNNGYLELAKQDYNNCQAQHQLEWDIFQKWYEE-NRLSEWGVRRSELLECY 566 N+ L AK DYN Q H+ E +W+++ + ++ R +ECY Sbjct: 210 --------FKNDLLLRFAKLDYNLLQMLHKHELSEVSRWWKDLDFVTTLPYARDRAVECY 261 Query: 567 YLAAATIFESERSHERMVWAKSSVLVKAISSSF 599 + E + S R++ AK+ ++ + +F Sbjct: 262 FWTMGVYAEPQYSQARVMLAKTIAMISIVDDTF 294 >3N0G-A nrPDB Length = 555 Score = 108 bits (271), Expect = 6e-24, Method: Compositional matrix adjust. Identities = 105/399 (26%), Positives = 178/399 (44%), Gaps = 51/399 (12%) Query: 288 FSPSSTAFAFMQTRDSN-CLEYLRNAVKRFNGGVP---NVFPVDLFEHIWIVDRLQRLGI 343 + P+S + F+ + D++ +E ++ K+ V N + + ++D +QRLG+ Sbjct: 20 YEPNSWDYDFLLSSDTDESIEVYKDKAKKLEAEVRREINNEKAEFLTLLELIDNVQRLGL 79 Query: 344 SRYFEEEIKECLDYVHRYWTDNGICWARCSHVQDIDDTAMAFRLLRQHGYQVSADVFKNF 403 FE +I+ LD R+ + G + + TA++FRLLRQHG++VS + F F Sbjct: 80 GYRFESDIRRALD---RFVSSGGFDGVTKTSLHA---TALSFRLLRQHGFEVSQEAFSGF 133 Query: 404 -EKEGEFFCFVGQSNQAVTGMFNLYRASQLAFPREEILKNAKEFSYNYLLEKREREELID 462 ++ G F + + +A+ +LY AS LA E IL A+ F+ ++L E E + Sbjct: 134 KDQNGNFLENLKEDTKAI---LSLYEASFLALEGENILDEARVFAISHLKELSEEK---- 186 Query: 463 KWIIMKDLPGEIGFALEIPWYASLPRVETRFYIDQYGGENDVWIGKTLYRMPYVNNNGYL 522 I K+L ++ ALE+P + R+E + I+ Y + D N L Sbjct: 187 ---IGKELAEQVNHALELPLHRRTQRLEAVWSIEAYRKKEDA-------------NQVLL 230 Query: 523 ELAKQDYNNCQAQHQLEWDIFQKWYEENRL-SEWGVRRSELLECYYLAAATIFESERSHE 581 ELA DYN Q+ +Q + +W+ L ++ R L+E +Y A FE + S Sbjct: 231 ELAILDYNMIQSVYQRDLRETSRWWRRVGLATKLHFARDRLIESFYWAVGVAFEPQYSDC 290 Query: 582 RMVWAKSSVLVKAISSSFG--ESSDSRRSFSDQFHEYIANARRSDHHFNDRNMRLDRPGS 639 R AK V I + + D F+D + NA D P Sbjct: 291 RNSVAKMFSFVTIIDDIYDVYGTLDELELFTDAVERWDVNAIN------------DLPDY 338 Query: 640 VQASRLAGVLIGTLNQMSFDLFMSHGRDVNNLLYLSWGD 678 ++ LA L T+N++++D G ++ L +W D Sbjct: 339 MKLCFLA--LYNTINEIAYDNLKDKGENILPYLTKAWAD 375 >2ONH-A nrPDB Length = 543 Score = 105 bits (262), Expect = 7e-23, Method: Compositional matrix adjust. Identities = 102/363 (28%), Positives = 168/363 (46%), Gaps = 44/363 (12%) Query: 326 VDLFEHIWIVDRLQRLGISRYFEEEIKECLDYV---HRYWTDNGICWARCSHVQDIDDTA 382 D + ++D LQR+G+S +F+ E KE L + H Y+ + +D+ T+ Sbjct: 48 TDQIRQLELIDDLQRMGLSDHFQNEFKEILSSIYLDHHYYKN-----PFPKEERDLYSTS 102 Query: 383 MAFRLLRQHGYQVSADVFKNFE-KEGEFFCFVGQSNQAVTGMFNLYRASQLAFPREEILK 441 +AFRLLR+HG+QV+ +VF +F+ +EGEF + + G+ LY AS L E L+ Sbjct: 103 LAFRLLREHGFQVAQEVFDSFKNEEGEFKESLSDDTR---GLLQLYEASFLLTEGETTLE 159 Query: 442 NAKEFSYNYLLEKREREELIDKWIIMKDLPGEIGFALEIPWYASLPRVETRFYIDQYGGE 501 +A+EF+ +L EE +++ + DL I ++L+IP + + R +I+ Y Sbjct: 160 SAREFATKFL------EEKVNEGGVDGDLLTRIAYSLDIPLHWRIKRPNAPVWIEWYRKR 213 Query: 502 NDVWIGKTLYRMPYVNNNGYLELAKQDYNNCQAQHQLEW-DIFQKWYEENRLSEWGVRRS 560 D+ N LELA D N QAQ Q E + F+ W + + R Sbjct: 214 PDM-------------NPVVLELAILDLNIVQAQFQEELKESFRWWRNTGFVEKLPFARD 260 Query: 561 ELLECYYLAAATIFESERSHERMVWAKSSVLVKAISSSFGESSDSRRSFSDQFHEYIANA 620 L+ECY+ I + + R++ K + L+ I + +QF + I Sbjct: 261 RLVECYFWNTGIIEPRQHASARIMMGKVNALITVIDDIYDVYGTLEE--LEQFTDLI--- 315 Query: 621 RRSDHHFNDRNMRLDRPGSVQASRLAGVLIGTLNQMSFDLFMSHGRDVNNLLYLSWGDWM 680 RR D + D+ P +Q LA L ++ S+D+ G +V L SW D Sbjct: 316 RRWDINSIDQ-----LPDYMQLCFLA--LNNFVDDTSYDVMKEKGVNVIPYLRQSWVDLA 368 Query: 681 EKW 683 +K+ Sbjct: 369 DKY 371 >4GAX-A nrPDB Length = 563 Score = 105 bits (261), Expect = 1e-22, Method: Compositional matrix adjust. Identities = 85/271 (31%), Positives = 130/271 (47%), Gaps = 47/271 (17%) Query: 334 IVDRLQRLGISRYFEEEIKECLDYVHRYWTDNGICWARCSHVQDIDDTAMAFRLLRQHGY 393 +VD +QRLGIS FE+EI L +++ + DN W+ +++ FRL+R+ GY Sbjct: 83 LVDEIQRLGISYLFEQEIDHALQHIYETYGDN---WSGAR-------SSLWFRLMRKQGY 132 Query: 394 QVSADVFKNFEKEGEFFCFVGQS-NQAVTGMFNLYRASQLAFPREEILKNAKEFSYNYLL 452 V+ DVF N + E F QS V G+ LY A+ + P E IL++A F+ ++L Sbjct: 133 FVTCDVFNNHKDESGVF---KQSLKNHVEGLLELYEATSMRVPGEIILEDALVFTQSHLS 189 Query: 453 EKREREELIDKWIIMKD-------LPGEIGFALEIPWYASLPRVETRFYIDQYGGENDVW 505 II KD L EI AL+ P + LPR+E YI Y ++ Sbjct: 190 ------------IIAKDTLSINPALSTEIQRALKKPLWKRLPRIEAVQYIPFYEQQDS-- 235 Query: 506 IGKTLYRMPYVNNNGYLELAKQDYNNCQAQHQLEWDIFQKWYEE-NRLSEWGVRRSELLE 564 +N ++LAK ++N Q+ H+ E KW++ + + R ++E Sbjct: 236 -----------HNKTLIKLAKLEFNLLQSLHREELSQLSKWWKAFDVKNNAPYSRDRIVE 284 Query: 565 CYYLAAATIFESERSHERMVWAKSSVLVKAI 595 CY+ A A+ FE + S R+ AK LV I Sbjct: 285 CYFWALASRFEPQYSRARIFLAKVIALVTLI 315 >6O9P-A nrPDB Length = 566 Score = 102 bits (255), Expect = 5e-22, Method: Compositional matrix adjust. Identities = 87/314 (27%), Positives = 143/314 (45%), Gaps = 42/314 (13%) Query: 295 FAFMQT--RDSNCLEYLRNAVKRFNGGVPNVF--PVDLFEHIWIVDRLQRLGISRYFEEE 350 + F+Q+ R S+ E ++ G V ++ P++ + +D ++RLG+ FE E Sbjct: 39 YDFLQSLGRHSSVTEEHVGLAEKLKGEVKSLITGPMEPLAKLEFIDSVRRLGLKYQFETE 98 Query: 351 IKECLDYVHR-----YWTDNGICWARCSHVQDIDDTAMAFRLLRQHGYQVSADVFKNFEK 405 +KE L + + +W DN + TA+ FRLLR++G V DVF+ F+ Sbjct: 99 MKEALANISKDGYDSWWVDN------------LRATALRFRLLRENGIFVPQDVFERFQN 146 Query: 406 EGEFFCFVGQSNQAVTGMFNLYRASQLAFPREEILKNAKEFSYNYLLEKREREELIDKWI 465 + E F + + V G+ NLY AS L + E+IL A+ FS L + ++ I Sbjct: 147 K-ETGKFKNELCEDVKGLLNLYEASFLGWEGEDILDEARTFSTAQL-------KNVEGKI 198 Query: 466 IMKDLPGEIGFALEIPWYASLPRVETRFYIDQYGGENDVWIGKTLYRMPYVNNNGYLELA 525 +L + AL++P + R E R++ID Y E D+ N L+ A Sbjct: 199 SSPNLAKIVHHALDLPLHWRAIRYEARWFIDIYEDEEDM-------------NPTLLKYA 245 Query: 526 KQDYNNCQAQHQLEWDIFQKWYEENRLSEWGVRRSELLECYYLAAATIFESERSHERMVW 585 K D+N Q+ HQ E +W+ L + R+ L++ Y A +FE R + Sbjct: 246 KLDFNIVQSFHQAEIGRLARWWVGTGLDKLPFARNGLIQSYMYAIGMLFEPHLGEVREME 305 Query: 586 AKSSVLVKAISSSF 599 AK L+ I + Sbjct: 306 AKVGALITTIDDVY 319 >5UV2-A nrPDB Length = 607 Score = 98.6 bits (244), Expect = 1e-20, Method: Compositional matrix adjust. Identities = 86/315 (27%), Positives = 145/315 (46%), Gaps = 37/315 (11%) Query: 288 FSPSSTAFAFMQTRDSNCL-EYLRNAVKRFNGGVPNVF-----PVDLFEHIWIVDRLQRL 341 + PS F+Q+ +SN E + + G V P+D E ++D LQRL Sbjct: 58 YQPSIWDHDFLQSLNSNYTDETYKRRAEELKGKVKTAIKDVTEPLDQLE---LIDNLQRL 114 Query: 342 GISRYFEEEIKECLDYVHRYWTDNGICWARCSHVQDIDDTAMAFRLLRQHGYQVSADVFK 401 G++ +FE EI+ L +H + D W + +++ T++ FRLLRQHGY VS +VF Sbjct: 115 GLAYHFEPEIRNILRNIHNHNKDYN--WRK----ENLYATSLEFRLLRQHGYPVSQEVFS 168 Query: 402 NFEKEGEFFCFVGQSNQAVTGMFNLYRASQLAFPREEILKNAKEFSYNYLLEKREREELI 461 F+ + VG G+ +L+ AS + E I++ A +F+ +L E Sbjct: 169 GFKDDK-----VGFICDDFKGILSLHEASYYSLEGESIMEEAWQFTSKHLKEMMITSNSK 223 Query: 462 DKWIIMKDLPGEIGFALEIPWYASLPRVETRFYIDQYGGENDVWIGKTLYRMPYVNNNGY 521 ++ + + + + ALE+P + P +E R++I Y D N+ Sbjct: 224 EEDVFVAE---QAKRALELPLHWKAPMLEARWFIHVYEKRED-------------KNHLL 267 Query: 522 LELAKQDYNNCQAQHQLEWDIFQKWYEENRLSE-WGVRRSELLECYYLAAATIFESERSH 580 LELAK ++N QA +Q E W+++ L E R+ L+ + + FE + ++ Sbjct: 268 LELAKLEFNTLQAIYQEELKDISGWWKDTGLGEKLSFARNRLVASFLWSMGIAFEPQFAY 327 Query: 581 ERMVWAKSSVLVKAI 595 R V S L+ I Sbjct: 328 CRRVLTISIALITVI 342 >1N1Z-A nrPDB Length = 549 Score = 94.4 bits (233), Expect = 2e-19, Method: Compositional matrix adjust. Identities = 87/296 (29%), Positives = 136/296 (45%), Gaps = 35/296 (11%) Query: 325 PVDLFEHIWIVDRLQRLGISRYFEEEIKECLDYV---HRYWTDNGICWARCSHVQDIDDT 381 PV E ++ L+ LG+S +F++EIKE L + H+ + +N + D+ T Sbjct: 54 PVQQLE---LIHDLKYLGLSDFFQDEIKEILGVIYNEHKCFHNNEV------EKMDLYFT 104 Query: 382 AMAFRLLRQHGYQVSADVFKNFEKEGEFFCFVGQSNQAVTGMFNLYRASQLAFPREEILK 441 A+ FRLLRQHG+ +S DVF F+ E + F Q GM LY AS L E+ L+ Sbjct: 105 ALGFRLLRQHGFNISQDVFNCFKNE-KGIDFKASLAQDTKGMLQLYEASFLLRKGEDTLE 163 Query: 442 NAKEFSYNYLLEK-REREELIDKWIIMKDLPGEIGFALEIPWYASLPRVETRFYIDQYGG 500 A+EF+ L +K E ID+ +++ I +L++P + + VE R++ID Y Sbjct: 164 LAREFATKCLQKKLDEGGNEIDENLLLW-----IRHSLDLPLHWRIQSVEARWFIDAYAR 218 Query: 501 ENDVWIGKTLYRMPYVNNNGYLELAKQDYNNCQAQHQLEWDIFQKWYEENRLSE-WGVRR 559 D+ N ELAK ++N QA HQ E +W+ E R Sbjct: 219 RPDM-------------NPLIFELAKLNFNIIQATHQQELKDLSRWWSRLCFPEKLPFVR 265 Query: 560 SELLECYYLAAATIFESERSHERMVWAKSSVLVKAISSSFG--ESSDSRRSFSDQF 613 L+E ++ A + ++R + A VL I + + D F+D F Sbjct: 266 DRLVESFFWAVGMFEPHQHGYQRKMAATIIVLATVIDDIYDVYGTLDELELFTDTF 321 >3G4D-A nrPDB Length = 554 Score = 88.6 bits (218), Expect = 9e-18, Method: Compositional matrix adjust. Identities = 80/279 (28%), Positives = 131/279 (46%), Gaps = 39/279 (13%) Query: 335 VDRLQRLGISRYFEEEIKECLDYVHRYWTDNGICWARCSHVQDIDDTAMAFRLLRQHGYQ 394 +D +QRLG+S +F +EI++ L+ ++ D D+ T++ FRLLR+HGY Sbjct: 77 IDSVQRLGVSYHFTKEIEDELENIYHNNNDAE---------NDLYTTSIRFRLLREHGYN 127 Query: 395 VSADVFKNFEKE-GEFFCFVGQSNQAVTGMFNLYRASQLAFPREEILKNAKEFSYNYLLE 453 VS DVF F+ E G F V V G+ LY+AS L E+IL A F+ ++L Sbjct: 128 VSCDVFNKFKDEQGNFKSSVTSD---VRGLLELYQASYLRVHGEDILDEAISFTTHHL-- 182 Query: 454 KREREELIDKWIIMKDLPGEIGFALEIPWYASLPRVETRFYIDQYGGENDVWIGKTLYRM 513 + + L E+ AL+ LPRVE R Y+ ++Y+ Sbjct: 183 ------SLAVASLDHPLSEEVSHALKQSIRRGLPRVEARHYL-------------SVYQD 223 Query: 514 PYVNNNGYLELAKQDYNNCQAQHQLEWDIFQKWYEE-NRLSEWGVRRSELLECYYLAAAT 572 +N LE AK D+N Q H+ E +W+++ + + R ++E Y+ + Sbjct: 224 IESHNKALLEFAKIDFNMLQFLHRKELSEICRWWKDLDFQRKLPYARDRVVEGYFWISGV 283 Query: 573 IFESERSHERMVWAKSSVLVKAISSSFGESSDSRRSFSD 611 FE + S R + K V A++S ++ DS ++ + Sbjct: 284 YFEPQYSLGRKMLTK----VIAMASIVDDTYDSYATYEE 318 >5C05-A nrPDB Length = 559 Score = 85.1 bits (209), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 80/283 (28%), Positives = 132/283 (46%), Gaps = 32/283 (11%) Query: 334 IVDRLQRLGISRYFEEEIKECLDYVHRYWTDNGICWARCSHVQDIDDTAMAFRLLRQHGY 393 +++ L+ LG++ YFE+E K+ L ++ N + V D+ T++AFRLLR HG+ Sbjct: 74 LIEDLRNLGLTYYFEDEFKKILTSIY-----NEHKGFKNEQVGDLYFTSLAFRLLRLHGF 128 Query: 394 QVSADVFKNFEKE--GEFFCFVGQSNQAVTGMFNLYRASQLAFPREEILKNAKEFSYNYL 451 VS DVF F+ E +F +G++ + V LY AS L E L+ A+ FS + Sbjct: 129 DVSEDVFNFFKNEDGSDFKASLGENTKDV---LELYEASFLIRVGEVTLEQARVFSTK-I 184 Query: 452 LEKREREELIDKWIIMKDLPGEIGFALEIPWYASLPRVETRFYIDQYGGENDVWIGKTLY 511 LEK+ E + D + L I +L +P + + R+E R+++D Y D+ Sbjct: 185 LEKKVEEGIKD-----EKLLAWIQHSLALPLHWRIQRLEARWFLDAYKARKDM------- 232 Query: 512 RMPYVNNNGYLELAKQDYNNCQ-AQHQLEWDIFQKWYEENRLSEWGVRRSELLECYYLAA 570 N EL K D++ Q Q Q ++ Q W N + R ++ECY+ A Sbjct: 233 ------NPIIYELGKIDFHIIQETQLQEVQEVSQWWTNTNLAEKLPFVRDRIVECYFWAL 286 Query: 571 ATIFESERSHERMVWAKSSVLVKAISSSFG--ESSDSRRSFSD 611 E ++R + A V I + ++ D + F+D Sbjct: 287 GLFEPHEYGYQRKMAAIIITFVTIIDDVYDVYDTLDELQLFTD 329 >3HW4-A nrPDB Length = 261 Score = 30.8 bits (68), Expect = 2.6, Method: Compositional matrix adjust. Identities = 16/34 (47%), Positives = 21/34 (61%), Gaps = 1/34 (2%) Query: 547 YEENRLSEWGVRRSELLECYYLAAATIFESERSH 580 Y+ENR E GV R E + YYL A +SE++H Sbjct: 117 YKENRFIEIGVTRRE-VHTYYLEKANKIKSEKTH 149 >4KIL-A nrPDB Length = 213 Score = 30.4 bits (67), Expect = 2.9, Method: Compositional matrix adjust. Identities = 16/34 (47%), Positives = 21/34 (61%), Gaps = 1/34 (2%) Query: 547 YEENRLSEWGVRRSELLECYYLAAATIFESERSH 580 Y+ENR E GV R E + YYL A +SE++H Sbjct: 121 YKENRFIEIGVTRRE-VHIYYLEKANKIKSEKTH 153 >4AWK-A nrPDB Length = 183 Score = 30.4 bits (67), Expect = 3.1, Method: Compositional matrix adjust. Identities = 16/34 (47%), Positives = 21/34 (61%), Gaps = 1/34 (2%) Query: 547 YEENRLSEWGVRRSELLECYYLAAATIFESERSH 580 Y+ENR E GV R E + YYL A +SE++H Sbjct: 97 YKENRFIEIGVTRRE-VHIYYLEKANKIKSEKTH 129 >4MK5-A nrPDB Length = 241 Score = 30.4 bits (67), Expect = 3.3, Method: Compositional matrix adjust. Identities = 16/34 (47%), Positives = 21/34 (61%), Gaps = 1/34 (2%) Query: 547 YEENRLSEWGVRRSELLECYYLAAATIFESERSH 580 Y+ENR E GV R E + YYL A +SE++H Sbjct: 149 YKENRFIEIGVTRRE-VHIYYLEKANKIKSEKTH 181 >3OQC-A nrPDB Length = 481 Score = 30.4 bits (67), Expect = 3.5, Method: Compositional matrix adjust. Identities = 18/57 (31%), Positives = 29/57 (50%), Gaps = 3/57 (5%) Query: 90 NSNAFKEAVKSVKTI---LRNLTDGEITISAYDTAWVALIDAGDKTPAFPSAVKWIA 143 + N + A +S++TI R+ E +I + AL+DAGDK F + +WI Sbjct: 308 DDNGWGSAYRSLQTICSWFRHQGYTERSIPTHREIQQALVDAGDKPATFVGSRQWIG 364 >2W69-A nrPDB Length = 216 Score = 29.6 bits (65), Expect = 6.0, Method: Compositional matrix adjust. Identities = 16/34 (47%), Positives = 20/34 (58%), Gaps = 1/34 (2%) Query: 547 YEENRLSEWGVRRSELLECYYLAAATIFESERSH 580 Y+ENR E GV R E + YYL A +SE +H Sbjct: 119 YKENRFIEIGVTRRE-VHIYYLEKANKIKSENTH 151 >2DER-A nrPDB Length = 380 Score = 28.9 bits (63), Expect = 8.8, Method: Compositional matrix adjust. Identities = 14/33 (42%), Positives = 23/33 (69%), Gaps = 1/33 (3%) Query: 380 DTAMAFRLLRQHGYQVSADVFKNFEK-EGEFFC 411 D++++ LL+Q GYQV KN+E+ +GE +C Sbjct: 29 DSSVSAWLLQQQGYQVEGLFMKNWEEDDGEEYC 61 >4TXE-A nrPDB Length = 294 Score = 28.9 bits (63), Expect = 9.3, Method: Compositional matrix adjust. Identities = 26/104 (25%), Positives = 43/104 (41%), Gaps = 8/104 (7%) Query: 259 TTLLHSLEGMRDLDWEKLLKLQSQDGSFLFSPSSTAFAFMQTRDSNCLEYLRNAVKRFNG 318 T + +E + L + LL L GS+LFS S A F QT E + + F+ Sbjct: 66 TQIAEDIETCQSLGKKVLLSLGGASGSYLFSDDSQAETFAQTLWDTFGEGTGASERPFDS 125 Query: 319 GVPNVFPVDL-----FEHIWIVDRLQRL---GISRYFEEEIKEC 354 V + F D+ + + +L+ L G +Y+ +C Sbjct: 126 AVVDGFDFDIENNNEVGYSALATKLRTLFAEGTKQYYLSAAPQC 169 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 4LIX-A nrPDB 1122 0.0 3S9V-A nrPDB 792 0.0 3SDU-A nrPDB 773 0.0 3P5P-A nrPDB 716 0.0 2ONH-A nrPDB 406 e-113 3N0G-A nrPDB 405 e-113 5UV2-A nrPDB 397 e-111 2J5C-A nrPDB 391 e-109 1N1Z-A nrPDB 388 e-108 6O9P-A nrPDB 372 e-103 5C05-A nrPDB 351 6e-97 5JO7-A nrPDB 347 8e-96 3M02-A nrPDB 342 3e-94 3G4D-A nrPDB 336 2e-92 4GAX-A nrPDB 309 3e-84 Sequences not found previously or not previously below threshold: 2FFQ-A nrPDB 39 0.007 5LEF-A nrPDB 37 0.022 2GIL-A nrPDB 37 0.029 4K0R-A nrPDB 34 0.24 2GLX-A nrPDB 32 0.80 4Z2M-B nrPDB 32 1.1 3K1D-A nrPDB 32 1.5 1D5C-A nrPDB 32 1.5 1VZO-A nrPDB 31 2.5 1UMP-A nrPDB 30 3.3 5NZU-C nrPDB 30 4.6 3KR9-A nrPDB 30 4.8 4N0I-A nrPDB 29 7.0 CONVERGED! >4LIX-A nrPDB Length = 727 Score = 1122 bits (2902), Expect = 0.0, Method: Composition-based stats. Identities = 718/718 (100%), Positives = 718/718 (100%) Query: 85 ISVGSNSNAFKEAVKSVKTILRNLTDGEITISAYDTAWVALIDAGDKTPAFPSAVKWIAE 144 ISVGSNSNAFKEAVKSVKTILRNLTDGEITISAYDTAWVALIDAGDKTPAFPSAVKWIAE Sbjct: 2 ISVGSNSNAFKEAVKSVKTILRNLTDGEITISAYDTAWVALIDAGDKTPAFPSAVKWIAE 61 Query: 145 NQLSDGSWGDAYLFSYHDRLINTLACVVALRSWNLFPHQCNKGITFFRENIGKLEDENDE 204 NQLSDGSWGDAYLFSYHDRLINTLACVVALRSWNLFPHQCNKGITFFRENIGKLEDENDE Sbjct: 62 NQLSDGSWGDAYLFSYHDRLINTLACVVALRSWNLFPHQCNKGITFFRENIGKLEDENDE 121 Query: 205 HMPIGFEVAFPSLLEIARGINIDVPYDSPVLKDIYAKKELKLTRIPKEIMHKIPTTLLHS 264 HMPIGFEVAFPSLLEIARGINIDVPYDSPVLKDIYAKKELKLTRIPKEIMHKIPTTLLHS Sbjct: 122 HMPIGFEVAFPSLLEIARGINIDVPYDSPVLKDIYAKKELKLTRIPKEIMHKIPTTLLHS 181 Query: 265 LEGMRDLDWEKLLKLQSQDGSFLFSPSSTAFAFMQTRDSNCLEYLRNAVKRFNGGVPNVF 324 LEGMRDLDWEKLLKLQSQDGSFLFSPSSTAFAFMQTRDSNCLEYLRNAVKRFNGGVPNVF Sbjct: 182 LEGMRDLDWEKLLKLQSQDGSFLFSPSSTAFAFMQTRDSNCLEYLRNAVKRFNGGVPNVF 241 Query: 325 PVDLFEHIWIVDRLQRLGISRYFEEEIKECLDYVHRYWTDNGICWARCSHVQDIDDTAMA 384 PVDLFEHIWIVDRLQRLGISRYFEEEIKECLDYVHRYWTDNGICWARCSHVQDIDDTAMA Sbjct: 242 PVDLFEHIWIVDRLQRLGISRYFEEEIKECLDYVHRYWTDNGICWARCSHVQDIDDTAMA 301 Query: 385 FRLLRQHGYQVSADVFKNFEKEGEFFCFVGQSNQAVTGMFNLYRASQLAFPREEILKNAK 444 FRLLRQHGYQVSADVFKNFEKEGEFFCFVGQSNQAVTGMFNLYRASQLAFPREEILKNAK Sbjct: 302 FRLLRQHGYQVSADVFKNFEKEGEFFCFVGQSNQAVTGMFNLYRASQLAFPREEILKNAK 361 Query: 445 EFSYNYLLEKREREELIDKWIIMKDLPGEIGFALEIPWYASLPRVETRFYIDQYGGENDV 504 EFSYNYLLEKREREELIDKWIIMKDLPGEIGFALEIPWYASLPRVETRFYIDQYGGENDV Sbjct: 362 EFSYNYLLEKREREELIDKWIIMKDLPGEIGFALEIPWYASLPRVETRFYIDQYGGENDV 421 Query: 505 WIGKTLYRMPYVNNNGYLELAKQDYNNCQAQHQLEWDIFQKWYEENRLSEWGVRRSELLE 564 WIGKTLYRMPYVNNNGYLELAKQDYNNCQAQHQLEWDIFQKWYEENRLSEWGVRRSELLE Sbjct: 422 WIGKTLYRMPYVNNNGYLELAKQDYNNCQAQHQLEWDIFQKWYEENRLSEWGVRRSELLE 481 Query: 565 CYYLAAATIFESERSHERMVWAKSSVLVKAISSSFGESSDSRRSFSDQFHEYIANARRSD 624 CYYLAAATIFESERSHERMVWAKSSVLVKAISSSFGESSDSRRSFSDQFHEYIANARRSD Sbjct: 482 CYYLAAATIFESERSHERMVWAKSSVLVKAISSSFGESSDSRRSFSDQFHEYIANARRSD 541 Query: 625 HHFNDRNMRLDRPGSVQASRLAGVLIGTLNQMSFDLFMSHGRDVNNLLYLSWGDWMEKWK 684 HHFNDRNMRLDRPGSVQASRLAGVLIGTLNQMSFDLFMSHGRDVNNLLYLSWGDWMEKWK Sbjct: 542 HHFNDRNMRLDRPGSVQASRLAGVLIGTLNQMSFDLFMSHGRDVNNLLYLSWGDWMEKWK 601 Query: 685 LYGDEGEGELMVKMIILMKNNDLTNFFTHTHFVRLAEIINRICLPRQYLKARRNDEKEKT 744 LYGDEGEGELMVKMIILMKNNDLTNFFTHTHFVRLAEIINRICLPRQYLKARRNDEKEKT Sbjct: 602 LYGDEGEGELMVKMIILMKNNDLTNFFTHTHFVRLAEIINRICLPRQYLKARRNDEKEKT 661 Query: 745 IKSMEKEMGKMVELALSESDTFRDVSITFLDVAKAFYYFALCGDHLQTHISKVLFQKV 802 IKSMEKEMGKMVELALSESDTFRDVSITFLDVAKAFYYFALCGDHLQTHISKVLFQKV Sbjct: 662 IKSMEKEMGKMVELALSESDTFRDVSITFLDVAKAFYYFALCGDHLQTHISKVLFQKV 719 >3S9V-A nrPDB Length = 785 Score = 792 bits (2044), Expect = 0.0, Method: Composition-based stats. Identities = 255/601 (42%), Positives = 367/601 (61%), Gaps = 17/601 (2%) Query: 87 VGSNSNAFKEAVKSVKTILRNLTDGEITISAYDTAWVALIDA--GDKTPAFPSAVKWIAE 144 S+ + + +K + R + GE SAYDTAWVA I A G P FP V+WI + Sbjct: 26 AASDEKRIETLISEIKNMFRCMGYGETNPSAYDTAWVARIPAVDGSDNPHFPETVEWILQ 85 Query: 145 NQLSDGSWGDAYLFSYHDRLINTLACVVALRSWNLFPHQCNKGITFFRENIGKLEDENDE 204 NQL DGSWG+ + F +DR++ TLAC++ L W Q KGI FFR GK+EDE D Sbjct: 86 NQLKDGSWGEGFYFLAYDRILATLACIITLTLWRTGETQVQKGIEFFRTQAGKMEDEADS 145 Query: 205 HMPIGFEVAFPSLLEIARGINIDVPYDSPVLKDIYAKKELKLTRIPKEIMHKIPTTLLHS 264 H P GFE+ FP++L+ A+ + +D+PYD P LK I K+E KL RIP ++++ +PTTLL+S Sbjct: 146 HRPSGFEIVFPAMLKEAKILGLDLPYDLPFLKQIIEKREAKLKRIPTDVLYALPTTLLYS 205 Query: 265 LEGMRDL-DWEKLLKLQSQDGSFLFSPSSTAFAFMQTRDSNCLEYLRNAVKRFNGGVPNV 323 LEG++++ DW+K++KLQS+DGSFL SP+STA FM+T + CL++L +K+F VP Sbjct: 206 LEGLQEIVDWQKIMKLQSKDGSFLSSPASTAAVFMRTGNKKCLDFLNFVLKKFGNHVPCH 265 Query: 324 FPVDLFEHIWIVDRLQRLGISRYFEEEIKECLDYVHRYWTDNGICWARCSHVQDIDDTAM 383 +P+DLFE +W VD ++RLGI R+F+EEIKE LDYV+ +W + GI WAR + V DIDDTAM Sbjct: 266 YPLDLFERLWAVDTVERLGIDRHFKEEIKEALDYVYSHWDERGIGWARENPVPDIDDTAM 325 Query: 384 AFRLLRQHGYQVSADVFKNFEKE-GEFFCFVGQSNQAVTGMFNLYRASQLAFPREEILKN 442 R+LR HGY VS+DV K F E GEFFCF+GQ+ + VT M N+ R S ++FP E I++ Sbjct: 326 GLRILRLHGYNVSSDVLKTFRDENGEFFCFLGQTQRGVTDMLNVNRCSHVSFPGETIMEE 385 Query: 443 AKEFSYNYLLEKREREELIDKWIIMKDLPGEIGFALEIPWYASLPRVETRFYIDQYGGEN 502 AK + YL E + DKW K++ GE+ +AL+ PW+ S+PR+E R YI+ Y G + Sbjct: 386 AKLCTERYLRNALENVDAFDKWAFKKNIRGEVEYALKYPWHKSMPRLEARSYIENY-GPD 444 Query: 503 DVWIGKTLYRMPYVNNNGYLELAKQDYNNCQAQHQLEWDIFQKWYEENRLSEWGVRRSEL 562 DVW+GKT+Y MPY++N YLELAK D+N Q+ HQ E ++W++ + ++ R + Sbjct: 445 DVWLGKTVYMMPYISNEKYLELAKLDFNKVQSIHQTELQDLRRWWKSSGFTDLNFTRERV 504 Query: 563 LECYYLAAATIFESERSHERMVWAKSSVLVKAISSSFGESSDSRRSFSDQFHEYIANARR 622 E Y+ A+ IFE E S R V+ K+S + + D + + +R Sbjct: 505 TEIYFSPASFIFEPEFSKCREVYTKTSNFTVILDDLYDAHGS-----LDDLKLFTESVKR 559 Query: 623 SDHHFNDRNMRLDRPGSVQASRLAGVLIGTLNQMSFDLFMSHGRDVNNLLYLSWGDWMEK 682 D D+ P ++ + T N ++ + GRDV + W +E Sbjct: 560 WDLSLVDQ-----MPQQMKICFVG--FYNTFNDIAKEGRERQGRDVLGYIQNVWKVQLEA 612 Query: 683 W 683 + Sbjct: 613 Y 613 >3SDU-A nrPDB Length = 817 Score = 773 bits (1995), Expect = 0.0, Method: Composition-based stats. Identities = 239/650 (36%), Positives = 362/650 (55%), Gaps = 25/650 (3%) Query: 43 SRSGSIHCSKLRTQEYINSQEVQHDLPLIHEWQQLQGEDAPQISVGSNSNAFKEAVKSVK 102 S+ S+ C T I H P + + + +P I A + V +K Sbjct: 8 SKVSSLVCDLSSTSGLIRRTANPH--PNVWGYDLVHSLKSPYIDSSYRERA-EVLVSEIK 64 Query: 103 TILRNLTDGE----ITISAYDTAWVALIDA--GDKTPAFPSAVKWIAENQLSDGSWGDAY 156 +L G+ IT SAYDTAWVA + A G P FP V WI +NQL DGSWG Sbjct: 65 AMLNPAITGDGESMITPSAYDTAWVARVPAIDGSARPQFPQTVDWILKNQLKDGSWGIQS 124 Query: 157 LFSYHDRLINTLACVVALRSWNLFPHQCNKGITFFRENIGKLEDENDE-HMPIGFEVAFP 215 F DRL+ TL+CV+ L WN+ Q +GI F + N+ ++DE D+ + FE+ FP Sbjct: 125 HFLLSDRLLATLSCVLVLLKWNVGDLQVEQGIEFIKSNLELVKDETDQDSLVTDFEIIFP 184 Query: 216 SLLEIARGINIDVPYDSPVLKDIYAKKELKLTRIPKEIMHKIPTTLLHSLEGMRDL-DWE 274 SLL A+ + + +PYD P + + K++ +L ++ +E ++ +P+ LL+SLEG++D+ +WE Sbjct: 185 SLLREAQSLRLGLPYDLPYIHLLQTKRQERLAKLSREEIYAVPSPLLYSLEGIQDIVEWE 244 Query: 275 KLLKLQSQDGSFLFSPSSTAFAFMQTRDSNCLEYLRNAVKRFNGGVPNVFPVDLFEHIWI 334 +++++QSQDGSFL SP+STA FM T D+ CLE+L + + +F VP ++PVDL E + I Sbjct: 245 RIMEVQSQDGSFLSSPASTACVFMHTGDAKCLEFLNSVMIKFGNFVPCLYPVDLLERLLI 304 Query: 335 VDRLQRLGISRYFEEEIKECLDYVHRYWTDNGICWARCSHVQDIDDTAMAFRLLRQHGYQ 394 VD + RLGI R+FE+EIKE LDYV+R+W + GI W R + + D++ TA+ FRLLR H Y Sbjct: 305 VDNIVRLGIYRHFEKEIKEALDYVYRHWNERGIGWGRLNPIADLETTALGFRLLRLHRYN 364 Query: 395 VSADVFKNFEK-EGEFFCFVGQSNQAVTGMFNLYRASQLAFPREEILKNAKEFSYNYLLE 453 VS +F NF+ G+F C GQ N+ V M NLYRASQLAFP E IL AK F+ YL E Sbjct: 365 VSPAIFDNFKDANGKFICSTGQFNKDVASMLNLYRASQLAFPGENILDEAKSFATKYLRE 424 Query: 454 KREREELIDKWIIMKDLPGEIGFALEIPWYASLPRVETRFYIDQYGGENDVWIGKTLYRM 513 E+ E W ++L EI +AL+ W+AS+PRVE + Y Y + I K +Y++ Sbjct: 425 ALEKSETSSAWNNKQNLSQEIKYALKTSWHASVPRVEAKRYCQVYRP-DYARIAKCVYKL 483 Query: 514 PYVNNNGYLELAKQDYNNCQAQHQLEWDIFQKWYEENRLSEWGVRRSELLECYYLAAATI 573 PYVNN +LEL K D+N Q+ HQ E W+ ++ L + R LE Y+L AA Sbjct: 484 PYVNNEKFLELGKLDFNIIQSIHQEEMKNVTSWFRDSGLPLFTFARERPLEFYFLVAAGT 543 Query: 574 FESERSHERMVWAKSSVLVKAISSSFGESSDSRRSFSDQFHEYIANARRSDHHFNDRNMR 633 +E + + R ++ K + L + + D+ + RR D F + Sbjct: 544 YEPQYAKCRFLFTKVACLQTVLDDMYDTYGT-----LDELKLFTEAVRRWDLSFTE---- 594 Query: 634 LDRPGSVQASRLAGVLIGTLNQMSFDLFMSHGRDVNNLLYLSWGDWMEKW 683 + P ++ + +++++++ GR++ + W D++ + Sbjct: 595 -NLPDYMKLCY--QIYYDIVHEVAWEAEKEQGRELVSFFRKGWEDYLLGY 641 >3P5P-A nrPDB Length = 764 Score = 716 bits (1847), Expect = 0.0, Method: Composition-based stats. Identities = 222/600 (37%), Positives = 334/600 (55%), Gaps = 33/600 (5%) Query: 85 ISVGSNSNAFKEAVKSVKTILRNLTDGEITISAYDTAWVALIDA----GDKTPAFPSAVK 140 + + E V +K + L DG+I+ SAYDTAWVA + G + P FP A+ Sbjct: 1 MESSTYQERADELVVKIKDMFNALGDGDISPSAYDTAWVARLATISSDGSEKPRFPQALN 60 Query: 141 WIAENQLSDGSWGDAYLFSYHDRLINTLACVVALRSWNLFPHQCNKGITFFRENIGKLED 200 W+ NQL DGSWG FS DRL+NT V+AL W Q +G F EN+ +L + Sbjct: 61 WVFNNQLQDGSWGIESHFSLCDRLLNTTNSVIALSVWKTGHSQVQQGAEFIAENL-RLLN 119 Query: 201 ENDEHMPIGFEVAFPSLLEIARGINIDVPYDSPVLKDIYAKKELKLTRIPKEIMHKIPTT 260 E DE P F++ FP+LL+ A+ + I++PYD P +K + +E +LT + IP Sbjct: 120 EEDELSP-DFQIIFPALLQKAKALGINLPYDLPFIKYLSTTREARLTDV-SAAADNIPAN 177 Query: 261 LLHSLEGMRD-LDWEKLLKLQSQDGSFLFSPSSTAFAFMQTRDSNCLEYLRNAVKRFNGG 319 +L++LEG+ + +DW K+++ QS+DGSFL SP+STA M T D C +L N + +F G Sbjct: 178 MLNALEGLEEVIDWNKIMRFQSKDGSFLSSPASTACVLMNTGDEKCFTFLNNLLDKFGGC 237 Query: 320 VPNVFPVDLFEHIWIVDRLQRLGISRYFEEEIKECLDYVHRYWTDNGICWARCSHVQDID 379 VP ++ +DL E + +VD ++ LGI R+F++EIK LDYV+R+W++ GI W R S V D++ Sbjct: 238 VPCMYSIDLLERLSLVDNIEHLGIGRHFKQEIKGALDYVYRHWSERGIGWGRDSLVPDLN 297 Query: 380 DTAMAFRLLRQHGYQVSADVFKNFEKE-GEFFCFVGQSNQAVTGMFNLYRASQLAFPREE 438 TA+ R LR HGY VS+DV NF+ E G FF GQ++ + + NL+RAS LAFP E Sbjct: 298 TTALGLRTLRMHGYNVSSDVLNNFKDENGRFFSSAGQTHVELRSVVNLFRASDLAFPDER 357 Query: 439 ILKNAKEFSYNYLLEKREREELIDKWIIMKDLPGEIGFALEIPWYASLPRVETRFYIDQY 498 + +A++F+ YL E L K L EI + +E PW+ S+PR+E R YID Y Sbjct: 358 AMDDARKFAEPYLREA-----LATKISTNTKLFKEIEYVVEYPWHMSIPRLEARSYIDSY 412 Query: 499 GGENDVWIGKTLYRMPYVNNNGYLELAKQDYNNCQAQHQLEWDIFQKWYEENRLSEWGVR 558 +N VW KTLYRMP ++N+ LELAK D+N Q+ HQ E + +W++E+ +++ Sbjct: 413 -DDNYVWQRKTLYRMPSLSNSKCLELAKLDFNIVQSLHQEELKLLTRWWKESGMADINFT 471 Query: 559 RSELLECYYLAAATIFESERSHERMVWAKSSVLVKAISSSFG--ESSDSRRSFSDQFHEY 616 R + E Y+ +A FE E S R+ + K L + D +SF++ + Sbjct: 472 RHRVAEVYFSSAT--FEPEYSATRIAFTKIGCLQVLFDDMADIFATLDELKSFTEGVKRW 529 Query: 617 IANARRSDHHFNDRNMRLDRPGSVQASRLAGVLIGTLNQMSFDLFMSHGRDVNNLLYLSW 676 D ++ + P +Q V + +++ D+ GRD+ + W Sbjct: 530 ------------DTSLLHEIPECMQTCF--KVWFKLMEEVNNDVVKVQGRDMLAHIRKPW 575 >2ONH-A nrPDB Length = 543 Score = 406 bits (1042), Expect = e-113, Method: Composition-based stats. Identities = 108/404 (26%), Positives = 178/404 (44%), Gaps = 47/404 (11%) Query: 288 FSPSSTAFAFMQTRDSNCLEYLRNAVKRFNGGVPNVF-----PVDLFEHIWIVDRLQRLG 342 ++PS F+Q+ S+ E V R + V V D + ++D LQR+G Sbjct: 7 YNPSRWDVNFIQSLLSDYKE--DKHVIRASELVTLVKMELEKETDQIRQLELIDDLQRMG 64 Query: 343 ISRYFEEEIKECLDYVH--RYWTDNGICWARCSHVQDIDDTAMAFRLLRQHGYQVSADVF 400 +S +F+ E KE L ++ ++ N +D+ T++AFRLLR+HG+QV+ +VF Sbjct: 65 LSDHFQNEFKEILSSIYLDHHYYKN----PFPKEERDLYSTSLAFRLLREHGFQVAQEVF 120 Query: 401 KNFEKEGEFFCFVGQSNQAVTGMFNLYRASQLAFPREEILKNAKEFSYNYLLEKREREEL 460 +F+ E F + G+ LY AS L E L++A+EF+ +L EK Sbjct: 121 DSFKNEEG--EFKESLSDDTRGLLQLYEASFLLTEGETTLESAREFATKFLEEK------ 172 Query: 461 IDKWIIMKDLPGEIGFALEIPWYASLPRVETRFYIDQYGGENDVWIGKTLYRMPYVNNNG 520 +++ + DL I ++L+IP + + R +I+ Y D+ N Sbjct: 173 VNEGGVDGDLLTRIAYSLDIPLHWRIKRPNAPVWIEWYRKRPDM-------------NPV 219 Query: 521 YLELAKQDYNNCQAQHQLEWDIFQKWYEENRL-SEWGVRRSELLECYYLAAATIFESERS 579 LELA D N QAQ Q E +W+ + R L+ECY+ I + + Sbjct: 220 VLELAILDLNIVQAQFQEELKESFRWWRNTGFVEKLPFARDRLVECYFWNTGIIEPRQHA 279 Query: 580 HERMVWAKSSVLVKAISSSFGESSDSRRSFSDQFHEYIANARRSDHHFNDRNMRLDRPGS 639 R++ K + L+ I + +QF + I RR D + D+ P Sbjct: 280 SARIMMGKVNALITVIDDIYDVYGTLEEL--EQFTDLI---RRWDINSIDQ-----LPDY 329 Query: 640 VQASRLAGVLIGTLNQMSFDLFMSHGRDVNNLLYLSWGDWMEKW 683 +Q LA L ++ S+D+ G +V L SW D +K+ Sbjct: 330 MQLCFLA--LNNFVDDTSYDVMKEKGVNVIPYLRQSWVDLADKY 371 >3N0G-A nrPDB Length = 555 Score = 405 bits (1040), Expect = e-113, Method: Composition-based stats. Identities = 103/403 (25%), Positives = 176/403 (43%), Gaps = 49/403 (12%) Query: 288 FSPSSTAFAFMQTRDSN-CLEYLRNAVKRFNGGVP---NVFPVDLFEHIWIVDRLQRLGI 343 + P+S + F+ + D++ +E ++ K+ V N + + ++D +QRLG+ Sbjct: 20 YEPNSWDYDFLLSSDTDESIEVYKDKAKKLEAEVRREINNEKAEFLTLLELIDNVQRLGL 79 Query: 344 SRYFEEEIKECLDYVHRYWTDNGICWARCSHVQDIDDTAMAFRLLRQHGYQVSADVFKNF 403 FE +I+ LD R+ + G + + TA++FRLLRQHG++VS + F F Sbjct: 80 GYRFESDIRRALD---RFVSSGGFDGVTKTS---LHATALSFRLLRQHGFEVSQEAFSGF 133 Query: 404 EKEGEFFCFVGQSNQAVTGMFNLYRASQLAFPREEILKNAKEFSYNYLLEKREREELIDK 463 + + F+ + + +LY AS LA E IL A+ F+ ++L E E + Sbjct: 134 KDQNG--NFLENLKEDTKAILSLYEASFLALEGENILDEARVFAISHLKELSEEK----- 186 Query: 464 WIIMKDLPGEIGFALEIPWYASLPRVETRFYIDQYGGENDVWIGKTLYRMPYVNNNGYLE 523 I K+L ++ ALE+P + R+E + I+ Y + D N LE Sbjct: 187 --IGKELAEQVNHALELPLHRRTQRLEAVWSIEAYRKKEDA-------------NQVLLE 231 Query: 524 LAKQDYNNCQAQHQLEWDIFQKWYEENRL-SEWGVRRSELLECYYLAAATIFESERSHER 582 LA DYN Q+ +Q + +W+ L ++ R L+E +Y A FE + S R Sbjct: 232 LAILDYNMIQSVYQRDLRETSRWWRRVGLATKLHFARDRLIESFYWAVGVAFEPQYSDCR 291 Query: 583 MVWAKSSVLVKAISSSFG--ESSDSRRSFSDQFHEYIANARRSDHHFNDRNMRLDRPGSV 640 AK V I + + D F+D + NA D P + Sbjct: 292 NSVAKMFSFVTIIDDIYDVYGTLDELELFTDAVERWDVNAIN------------DLPDYM 339 Query: 641 QASRLAGVLIGTLNQMSFDLFMSHGRDVNNLLYLSWGDWMEKW 683 + LA L T+N++++D G ++ L +W D + Sbjct: 340 KLCFLA--LYNTINEIAYDNLKDKGENILPYLTKAWADLCNAF 380 >5UV2-A nrPDB Length = 607 Score = 397 bits (1020), Expect = e-111, Method: Composition-based stats. Identities = 95/402 (23%), Positives = 175/402 (43%), Gaps = 46/402 (11%) Query: 288 FSPSSTAFAFMQTRDSNCL-EYLRNAVKRFNGGVPNVFP--VDLFEHIWIVDRLQRLGIS 344 + PS F+Q+ +SN E + + G V + + + ++D LQRLG++ Sbjct: 58 YQPSIWDHDFLQSLNSNYTDETYKRRAEELKGKVKTAIKDVTEPLDQLELIDNLQRLGLA 117 Query: 345 RYFEEEIKECLDYVHRYWTDNGICWARCSHVQDIDDTAMAFRLLRQHGYQVSADVFKNFE 404 +FE EI+ L +H + D W + + + T++ FRLLRQHGY VS +VF F+ Sbjct: 118 YHFEPEIRNILRNIHNHNKDYN--WRKEN----LYATSLEFRLLRQHGYPVSQEVFSGFK 171 Query: 405 KEGEFFCFVGQSNQAVTGMFNLYRASQLAFPREEILKNAKEFSYNYLLEKREREELIDKW 464 + VG G+ +L+ AS + E I++ A +F+ +L E ++ Sbjct: 172 DDK-----VGFICDDFKGILSLHEASYYSLEGESIMEEAWQFTSKHLKEMMITSNSKEED 226 Query: 465 IIMKDLPGEIGFALEIPWYASLPRVETRFYIDQYGGENDVWIGKTLYRMPYVNNNGYLEL 524 + + + ALE+P + P +E R++I Y D N+ LEL Sbjct: 227 VF---VAEQAKRALELPLHWKAPMLEARWFIHVYEKRED-------------KNHLLLEL 270 Query: 525 AKQDYNNCQAQHQLEWDIFQKWYEENRL-SEWGVRRSELLECYYLAAATIFESERSHERM 583 AK ++N QA +Q E W+++ L + R+ L+ + + FE + ++ R Sbjct: 271 AKLEFNTLQAIYQEELKDISGWWKDTGLGEKLSFARNRLVASFLWSMGIAFEPQFAYCRR 330 Query: 584 VWAKSSVLVKAISSSFG--ESSDSRRSFSDQFHEYIANARRSDHHFNDRNMRLDRPGSVQ 641 V S L+ I + + D F+D R D ++ ++ PG ++ Sbjct: 331 VLTISIALITVIDDIYDVYGTLDELEIFTDAVA-------RWDINYALKH----LPGYMK 379 Query: 642 ASRLAGVLIGTLNQMSFDLFMSHGRDVNNLLYLSWGDWMEKW 683 LA L +N+ ++ + D+ + +W ++ + Sbjct: 380 MCFLA--LYNFVNEFAYYVLKQQDFDMLLSIKHAWLGLIQAY 419 >2J5C-A nrPDB Length = 569 Score = 391 bits (1005), Expect = e-109, Method: Composition-based stats. Identities = 113/402 (28%), Positives = 175/402 (43%), Gaps = 49/402 (12%) Query: 288 FSPSSTAFAFMQTRDSNCLEYLRNAVKRFNGGVPNV-----FPVDLFEHIWIVDRLQRLG 342 + P+ F+ +Q+ DS E + R G + V VD + ++D L+RLG Sbjct: 40 YQPTLWDFSTIQSFDSEYKE--EKHLMRAAGMIDQVKMMLQEEVDSIRRLELIDDLRRLG 97 Query: 343 ISRYFEEEIKECLDYVHRYWTDNGICWARCSHVQDIDDTAMAFRLLRQHGYQVSADVFKN 402 IS +FE EI E L+ +Y+T+N I +D+ TA+ FRLLRQ+ + VS +VF Sbjct: 98 ISCHFEREIVEILNS--KYYTNNEI------DERDLYSTALRFRLLRQYDFSVSQEVFDC 149 Query: 403 FEKEGEFFCFVGQSNQAVTGMFNLYRASQLAFPREEILKNAKEFSYNYLLEKREREELID 462 F+ + F G+ LY AS L+ EE L+ A++F+ +L + L+D Sbjct: 150 FKN-AKGTDFKPSLVDDTRGLLQLYEASFLSAQGEETLRLARDFATKFLQ----KRVLVD 204 Query: 463 KWIIMKDLPGEIGFALEIPWYASLPRVETRFYIDQYGGENDVWIGKTLYRMPYVNNNGYL 522 K I +L I ALE+P + + R +ID Y D+ N L Sbjct: 205 KDI---NLLSSIERALELPTHWRVQMPNARSFIDAYKRRPDM-------------NPTVL 248 Query: 523 ELAKQDYNNCQAQHQLEWDIFQKWYEENRL-SEWGVRRSELLECYYLAAATIFESERSHE 581 ELAK D+N QAQ Q E +W+ L E R ++ECYY + + +E Sbjct: 249 ELAKLDFNMVQAQFQQELKEASRWWNSTGLVHELPFVRDRIVECYYWTTGVVERRQHGYE 308 Query: 582 RMVWAKSSVLVKAISSSFGESSDSRRSFSDQFHEYIANARRSDHHFNDRNMRLDRPGSVQ 641 R++ K + LV I F ++ + +R D + P +Q Sbjct: 309 RIMLTKINALVTTIDDVFDIYGT-----LEELQLFTTAIQRWDIESMKQ-----LPPYMQ 358 Query: 642 ASRLAGVLIGTLNQMSFDLFMSHGRDVNNLLYLSWGDWMEKW 683 LA L +N+M++D G D L W +E + Sbjct: 359 ICYLA--LFNFVNEMAYDTLRDKGFDSTPYLRKVWVGLIESY 398 >1N1Z-A nrPDB Length = 549 Score = 388 bits (996), Expect = e-108, Method: Composition-based stats. Identities = 98/407 (24%), Positives = 170/407 (41%), Gaps = 51/407 (12%) Query: 288 FSPSSTAFAFMQTRDSNCLEYLRNAVKRFNGGVPNV-----FPVDLFEHIWIVDRLQRLG 342 + P+ ++Q+ ++ E + R + V ++ + + ++ L+ LG Sbjct: 11 YQPALWDSNYIQSLNTPYTE--ERHLDRKAELIVQVRILLKEKMEPVQQLELIHDLKYLG 68 Query: 343 ISRYFEEEIKECLDYVH---RYWTDNGICWARCSHVQDIDDTAMAFRLLRQHGYQVSADV 399 +S +F++EIKE L ++ + + +N + D+ TA+ FRLLRQHG+ +S DV Sbjct: 69 LSDFFQDEIKEILGVIYNEHKCFHNNEV------EKMDLYFTALGFRLLRQHGFNISQDV 122 Query: 400 FKNFEKEGEFFCFVGQSNQAVTGMFNLYRASQLAFPREEILKNAKEFSYNYLLEKREREE 459 F F+ E + F Q GM LY AS L E+ L+ A+EF+ L +K + Sbjct: 123 FNCFKNE-KGIDFKASLAQDTKGMLQLYEASFLLRKGEDTLELAREFATKCLQKKLDEGG 181 Query: 460 LIDKWIIMKDLPGEIGFALEIPWYASLPRVETRFYIDQYGGENDVWIGKTLYRMPYVNNN 519 I ++L I +L++P + + VE R++ID Y D+ N Sbjct: 182 NE----IDENLLLWIRHSLDLPLHWRIQSVEARWFIDAYARRPDM-------------NP 224 Query: 520 GYLELAKQDYNNCQAQHQLEWDIFQKWYEENRLS-EWGVRRSELLECYYLAAATIFESER 578 ELAK ++N QA HQ E +W+ + R L+E ++ A + Sbjct: 225 LIFELAKLNFNIIQATHQQELKDLSRWWSRLCFPEKLPFVRDRLVESFFWAVGMFEPHQH 284 Query: 579 SHERMVWAKSSVLVKAISSSFG--ESSDSRRSFSDQFHEYIANARRSDHHFNDRNMRLDR 636 ++R + A VL I + + D F+D F R D R Sbjct: 285 GYQRKMAATIIVLATVIDDIYDVYGTLDELELFTDTFK-------RWDTESITR-----L 332 Query: 637 PGSVQASRLAGVLIGTLNQMSFDLFMSHGRDVNNLLYLSWGDWMEKW 683 P +Q + ++ ++D+ HG L S D +E + Sbjct: 333 PYYMQLCY--WGVHNYISDAAYDILKEHGFFCLQYLRKSVVDLVEAY 377 >6O9P-A nrPDB Length = 566 Score = 372 bits (954), Expect = e-103, Method: Composition-based stats. Identities = 99/402 (24%), Positives = 171/402 (42%), Gaps = 48/402 (11%) Query: 288 FSPSSTAFAFMQT--RDSNCLEYLRNAVKRFNGGVPNVF--PVDLFEHIWIVDRLQRLGI 343 + + + F+Q+ R S+ E ++ G V ++ P++ + +D ++RLG+ Sbjct: 32 YPANLWDYDFLQSLGRHSSVTEEHVGLAEKLKGEVKSLITGPMEPLAKLEFIDSVRRLGL 91 Query: 344 SRYFEEEIKECLDYVHRYWTDNGICWARCSHVQDIDDTAMAFRLLRQHGYQVSADVFKNF 403 FE E+KE L + + D W V ++ TA+ FRLLR++G V DVF+ F Sbjct: 92 KYQFETEMKEALANISK---DGYDSWW----VDNLRATALRFRLLRENGIFVPQDVFERF 144 Query: 404 EKEGEFFCFVGQSNQAVTGMFNLYRASQLAFPREEILKNAKEFSYNYLLEKREREELIDK 463 + + E F + + V G+ NLY AS L + E+IL A+ FS L ++ Sbjct: 145 QNK-ETGKFKNELCEDVKGLLNLYEASFLGWEGEDILDEARTFSTAQLKN-------VEG 196 Query: 464 WIIMKDLPGEIGFALEIPWYASLPRVETRFYIDQYGGENDVWIGKTLYRMPYVNNNGYLE 523 I +L + AL++P + R E R++ID Y E D+ N L+ Sbjct: 197 KISSPNLAKIVHHALDLPLHWRAIRYEARWFIDIYEDEEDM-------------NPTLLK 243 Query: 524 LAKQDYNNCQAQHQLEWDIFQKWYEENRLSEWGVRRSELLECYYLAAATIFESERSHERM 583 AK D+N Q+ HQ E +W+ L + R+ L++ Y A +FE R Sbjct: 244 YAKLDFNIVQSFHQAEIGRLARWWVGTGLDKLPFARNGLIQSYMYAIGMLFEPHLGEVRE 303 Query: 584 VWAKSSVLVKAISSSFG--ESSDSRRSFSDQFHEYIANARRSDHHFNDRNMRLDRPGSVQ 641 + AK L+ I + + + F+D R D + D+ P +++ Sbjct: 304 MEAKVGALITTIDDVYDVYGTMEELELFTDITE-------RWDINRVDQ-----LPRNIR 351 Query: 642 ASRLAGVLIGTLNQMSFDLFMSHGRDVNNLLYLSWGDWMEKW 683 L + T N + + G + W D ++ + Sbjct: 352 MPLL--TMFNTSNDIGYWALKERGFNGIPYTAKVWADQLKSY 391 >5C05-A nrPDB Length = 559 Score = 351 bits (901), Expect = 6e-97, Method: Composition-based stats. Identities = 92/405 (22%), Positives = 170/405 (41%), Gaps = 50/405 (12%) Query: 288 FSPSSTAFAFMQTRDSNCLEYLRNAVKR----FNGGVPNVFPVDLFEHIWIVDRLQRLGI 343 + F+Q+ ++ + + K+ V ++ + + +++ L+ LG+ Sbjct: 24 YQAPVWNNDFIQSFSTDKYKDEKFLKKKEELIAQVKVLLNTKMEAVKQLELIEDLRNLGL 83 Query: 344 SRYFEEEIKECLDYVHRYWTDNGICWARCSHVQDIDDTAMAFRLLRQHGYQVSADVFKNF 403 + YFE+E K+ L ++ N + V D+ T++AFRLLR HG+ VS DVF F Sbjct: 84 TYYFEDEFKKILTSIY-----NEHKGFKNEQVGDLYFTSLAFRLLRLHGFDVSEDVFNFF 138 Query: 404 EKE--GEFFCFVGQSNQAVTGMFNLYRASQLAFPREEILKNAKEFSYNYLLEKREREELI 461 + E +F +G++ + V LY AS L E L+ A+ FS L +K + Sbjct: 139 KNEDGSDFKASLGENTKDV---LELYEASFLIRVGEVTLEQARVFSTKILEKK------V 189 Query: 462 DKWIIMKDLPGEIGFALEIPWYASLPRVETRFYIDQYGGENDVWIGKTLYRMPYVNNNGY 521 ++ I + L I +L +P + + R+E R+++D Y D+ N Sbjct: 190 EEGIKDEKLLAWIQHSLALPLHWRIQRLEARWFLDAYKARKDM-------------NPII 236 Query: 522 LELAKQDYNNCQAQHQLEWDIFQKWY-EENRLSEWGVRRSELLECYYLAAATIFESERSH 580 EL K D++ Q E +W+ N + R ++ECY+ A E + Sbjct: 237 YELGKIDFHIIQETQLQEVQEVSQWWTNTNLAEKLPFVRDRIVECYFWALGLFEPHEYGY 296 Query: 581 ERMVWAKSSVLVKAISSSFG--ESSDSRRSFSDQFHEYIANARRSDHHFNDRNMRLDRPG 638 +R + A V I + ++ D + F+D R+ D P Sbjct: 297 QRKMAAIIITFVTIIDDVYDVYDTLDELQLFTDAI-------RKWDVESIST-----LPY 344 Query: 639 SVQASRLAGVLIGTLNQMSFDLFMSHGRDVNNLLYLSWGDWMEKW 683 +Q LA + +++++D+ G + + L SW +E + Sbjct: 345 YMQVCYLA--VFTYASELAYDILKDQGFNSISYLQRSWLSLVEGF 387 >5JO7-A nrPDB Length = 538 Score = 347 bits (891), Expect = 8e-96, Method: Composition-based stats. Identities = 96/406 (23%), Positives = 170/406 (41%), Gaps = 46/406 (11%) Query: 284 GSFLFSPSSTAFAFMQ-TRDSNCLEYLRNAVKRFNGGVPNVFP----VDLFEHIWIVDRL 338 GS + SPS F + D+ E ++ + L E + ++D + Sbjct: 1 GSHMASPSLWGDRFHSFSVDNQVAEKYAQEIETLKEQTSTMLSAACGTTLTEKLNLIDII 60 Query: 339 QRLGISRYFEEEIKECLDYVHRYWTDNGICWARCSHVQDIDDTAMAFRLLRQHGYQVSAD 398 +RLGI+ +FE++I++ LD+++R + D++ +++ FRLLRQHGY VS + Sbjct: 61 ERLGIAYHFEKQIEDMLDHIYR-----ADPYFEAHEYNDLNTSSVQFRLLRQHGYNVSPN 115 Query: 399 VFKNFEKEGEFFCFVGQSNQAVTGMFNLYRASQLAFPREEILKNAKEFSYNYLLEKRERE 458 +F F+ F +S + G+ NLY AS + +E+IL+ A FS +L Sbjct: 116 IFSRFQDANGKFKESLRS--DIRGLLNLYEASHVRTHKEDILEEALVFSVGHLESAAPH- 172 Query: 459 ELIDKWIIMKDLPGEIGFALEIPWYASLPRVETRFYIDQYGGENDVWIGKTLYRMPYVNN 518 + L ++ ALE + S+PRVE R++I Y E N Sbjct: 173 -------LKSPLSKQVTHALEQSLHKSIPRVEIRYFISIYEEEE-------------FKN 212 Query: 519 NGYLELAKQDYNNCQAQHQLEWDIFQKWYEE-NRLSEWGVRRSELLECYYLAAATIFESE 577 + L AK DYN Q H+ E +W+++ + ++ R +ECY+ E + Sbjct: 213 DLLLRFAKLDYNLLQMLHKHELSEVSRWWKDLDFVTTLPYARDRAVECYFWTMGVYAEPQ 272 Query: 578 RSHERMVWAKSSVLVKAISSSFGESSDSRRSFSDQFHEYIANARRSDHHFNDRNMRLDRP 637 S R++ AK+ ++ + +F + Y +R D DR P Sbjct: 273 YSQARVMLAKTIAMISIVDDTFDAYG-----IVKELEVYTDAIQRWDISQIDR-----LP 322 Query: 638 GSVQASRLAGVLIGTLNQMSFDLFMSHGRDVNNLLYLSWGDWMEKW 683 ++ S A L+ + +L DV + + + + Sbjct: 323 EYMKISYKA--LLDLYDDYEKELSKDGRSDVVHYAKERMKEIVRNY 366 >3M02-A nrPDB Length = 550 Score = 342 bits (878), Expect = 3e-94, Method: Composition-based stats. Identities = 92/364 (25%), Positives = 160/364 (43%), Gaps = 47/364 (12%) Query: 288 FSPSSTAFAFMQ-TRDSNCLEYLRNAVKRFNGGVPNVF---PVDLFEHIWIVDRLQRLGI 343 FSPS F+ + + E ++ N+ + L + + ++D ++RLGI Sbjct: 22 FSPSLWGDQFLSFSIKNQVAEKYAKEIEALKEQTRNMLLATGMKLADTLNLIDTIERLGI 81 Query: 344 SRYFEEEIKECLDYVHRYWTDNGICWARCSHVQDIDDTAMAFRLLRQHGYQVSADVFKNF 403 S +FE+EI + LD ++ ++ D+ +A+ FRLLRQHG+ +S ++F F Sbjct: 82 SYHFEKEIDDILDQIYNQNSN----------CNDLCTSALQFRLLRQHGFNISPEIFSKF 131 Query: 404 EKEGEFFCFVGQSNQAVTGMFNLYRASQLAFPREEILKNAKEFSYNYLLEKREREELIDK 463 + E F S V G+ NLY AS + ++IL++A FS +L Sbjct: 132 QDENGKFKESLAS--DVLGLLNLYEASHVRTHADDILEDALAFSTIHLESAAPH------ 183 Query: 464 WIIMKDLPGEIGFALEIPWYASLPRVETRFYIDQYGGENDVWIGKTLYRMPYVNNNGYLE 523 + L ++ ALE + +PRVETRF+I ++Y NN L Sbjct: 184 --LKSPLREQVTHALEQCLHKGVPRVETRFFI------------SSIYDKEQSKNNVLLR 229 Query: 524 LAKQDYNNCQAQHQLEWDIFQKWYEE-NRLSEWGVRRSELLECYYLAAATIFESERSHER 582 AK D+N Q H+ E +W+++ + ++ R ++ECY+ A FE + S R Sbjct: 230 FAKLDFNLLQMLHKQELAQVSRWWKDLDFVTTLPYARDRVVECYFWALGVYFEPQYSQAR 289 Query: 583 MVWAKSSVLVKAISSSFGESSDSRRSFSDQFHEYIANARRSDHHFNDRNMRLDRPGSVQA 642 ++ K+ ++ + +F + Y +R D + DR P ++ Sbjct: 290 VMLVKTISMISIVDDTFDAYGTVKEL-----EAYTDAIQRWDINEIDR-----LPDYMKI 339 Query: 643 SRLA 646 S A Sbjct: 340 SYKA 343 >3G4D-A nrPDB Length = 554 Score = 336 bits (862), Expect = 2e-92, Method: Composition-based stats. Identities = 93/402 (23%), Positives = 161/402 (40%), Gaps = 42/402 (10%) Query: 288 FSPSSTAFAFMQTRDSNCLEYLRNAVKRFNGGVPNVF--PV-DLFEHIWIVDRLQRLGIS 344 F PS F+ D N ++ V + P+ + + + +D +QRLG+S Sbjct: 27 FQPSIWGDLFLNCPDKNIDAETEKRHQQLKEEVRKMIVAPMANSTQKLAFIDSVQRLGVS 86 Query: 345 RYFEEEIKECLDYVHRYWTDNGICWARCSHVQDIDDTAMAFRLLRQHGYQVSADVFKNFE 404 +F +EI++ L+ ++ D D+ T++ FRLLR+HGY VS DVF F+ Sbjct: 87 YHFTKEIEDELENIYHNNNDAE---------NDLYTTSIRFRLLREHGYNVSCDVFNKFK 137 Query: 405 KEGEFFCFVGQSNQAVTGMFNLYRASQLAFPREEILKNAKEFSYNYLLEKREREELIDKW 464 E F V G+ LY+AS L E+IL A F+ ++L + Sbjct: 138 DEQGNFKS--SVTSDVRGLLELYQASYLRVHGEDILDEAISFTTHHL--------SLAVA 187 Query: 465 IIMKDLPGEIGFALEIPWYASLPRVETRFYIDQYGGENDVWIGKTLYRMPYVNNNGYLEL 524 + L E+ AL+ LPRVE R Y+ Y +N LE Sbjct: 188 SLDHPLSEEVSHALKQSIRRGLPRVEARHYLSVYQD-------------IESHNKALLEF 234 Query: 525 AKQDYNNCQAQHQLEWDIFQKWYEE-NRLSEWGVRRSELLECYYLAAATIFESERSHERM 583 AK D+N Q H+ E +W+++ + + R ++E Y+ + FE + S R Sbjct: 235 AKIDFNMLQFLHRKELSEICRWWKDLDFQRKLPYARDRVVEGYFWISGVYFEPQYSLGRK 294 Query: 584 VWAKSSVLVKAISSSFGESSDSRRSFSDQFHEYIANARRSDHHFNDRNMRLDRPGSVQAS 643 + K + + ++ DS ++ ++ Y R D D +P Sbjct: 295 MLTKVIAMASIVDDTY----DSYATY-EELIPYTNAIERWDIKCIDEIPEYMKPSYKALL 349 Query: 644 RLAGVLIGTLNQMSFDLFMSHGRDVNNLLYLSWGDWMEKWKL 685 + ++ + + + + ++ L S+ KW L Sbjct: 350 DVYEEMVQLVAEHGRQYRVEYAKNAMIRLAQSYL-VEAKWTL 390 >4GAX-A nrPDB Length = 563 Score = 309 bits (791), Expect = 3e-84, Method: Composition-based stats. Identities = 98/390 (25%), Positives = 161/390 (41%), Gaps = 50/390 (12%) Query: 288 FSPSSTAFAFMQTRDSNCLEYLRNAVKRFNGGVPNV------FPVDLFEHIWIVDRLQRL 341 FSPS F+ D+ + + VK V + P+ + +VD +QRL Sbjct: 32 FSPSIWGDQFLIV-DNQVEQGVEQIVKDLKKEVRQLLKEALDIPMKHANLLKLVDEIQRL 90 Query: 342 GISRYFEEEIKECLDYVHRYWTDNGICWARCSHVQDIDDTAMAFRLLRQHGYQVSADVFK 401 GIS FE+EI L +++ + DN W+ +++ FRL+R+ GY V+ DVF Sbjct: 91 GISYLFEQEIDHALQHIYETYGDN---WSGAR-------SSLWFRLMRKQGYFVTCDVFN 140 Query: 402 NFEKEGEFFCFVGQSNQAVTGMFNLYRASQLAFPREEILKNAKEFSYNYLLEKREREELI 461 N + E F V G+ LY A+ + P E IL++A F+ ++L Sbjct: 141 NHKDESGVFKQ--SLKNHVEGLLELYEATSMRVPGEIILEDALVFTQSHLSIIA-----K 193 Query: 462 DKWIIMKDLPGEIGFALEIPWYASLPRVETRFYIDQYGGENDVWIGKTLYRMPYVNNNGY 521 D I L EI AL+ P + LPR+E YI Y ++ +N Sbjct: 194 DTLSINPALSTEIQRALKKPLWKRLPRIEAVQYIPFYEQQD-------------SHNKTL 240 Query: 522 LELAKQDYNNCQAQHQLEWDIFQKWYEE-NRLSEWGVRRSELLECYYLAAATIFESERSH 580 ++LAK ++N Q+ H+ E KW++ + + R ++ECY+ A A+ FE + S Sbjct: 241 IKLAKLEFNLLQSLHREELSQLSKWWKAFDVKNNAPYSRDRIVECYFWALASRFEPQYSR 300 Query: 581 ERMVWAKSSVLVKAISSSFGESSDSRRSFSDQFHEYIANARRSDHHFNDRNMRLDRPGSV 640 R+ AK LV I + ++ + R D P + Sbjct: 301 ARIFLAKVIALVTLIDDIYDAYGT-----YEELKIFTEAIERWSITCLDM-----IPEYM 350 Query: 641 QASRLAGVLIGTLNQMSFDLFMSHGRDVNN 670 + + + T +M L ++ N Sbjct: 351 KPIY--KLFMDTYTEMEEILAKEGKTNIFN 378 >2FFQ-A nrPDB Length = 171 Score = 39.3 bits (90), Expect = 0.007, Method: Composition-based stats. Identities = 29/152 (19%), Positives = 58/152 (38%), Gaps = 14/152 (9%) Query: 585 WAKSSVLVKAISSSFGESSD-----SRRSFSDQFHEYIANARRSDHHFNDRNMRLDRPGS 639 K+S++ + + SF + S + + + D +R R P Sbjct: 13 VGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTVRLQLWDTAGQER-FRSLIPSY 71 Query: 640 VQASRLAGVLIGTLNQMSF--------DLFMSHGRDVNNLLYLSWGDWMEKWKLYGDEGE 691 ++ S +A V+ N SF D+ G DV +L + D +K ++ +EGE Sbjct: 72 IRDSTVAVVVYDITNLNSFQQTSKWIDDVRTERGSDVIIMLVGNKTDLADKRQITIEEGE 131 Query: 692 GELMVKMIILMKNNDLTNFFTHTHFVRLAEII 723 ++ ++ + T + F R+A + Sbjct: 132 QRAKELSVMFIETSAKTGYNVKQLFRRVASAL 163 >5LEF-A nrPDB Length = 191 Score = 37.4 bits (85), Expect = 0.022, Method: Composition-based stats. Identities = 25/120 (20%), Positives = 46/120 (38%), Gaps = 14/120 (11%) Query: 585 WAKSSVLVKAISSSFGESSD-----SRRSFSDQFHEYIANARRSDHHFNDRNMRLDRPGS 639 K+S++ + + SF + S + + + D +R R P Sbjct: 20 VGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTVRLQLWDTAGLER-FRSLIPSY 78 Query: 640 VQASRLAGVLIGTLNQMSF--------DLFMSHGRDVNNLLYLSWGDWMEKWKLYGDEGE 691 ++ S +A V+ N SF D+ G DV +L + D +K ++ +EGE Sbjct: 79 IRDSTVAVVVYDITNVNSFQQTTKWIDDVRTERGSDVIIMLVGNKTDLADKRQVSIEEGE 138 >2GIL-A nrPDB Length = 162 Score = 37.0 bits (84), Expect = 0.029, Method: Composition-based stats. Identities = 25/120 (20%), Positives = 46/120 (38%), Gaps = 14/120 (11%) Query: 585 WAKSSVLVKAISSSFGESSD-----SRRSFSDQFHEYIANARRSDHHFNDRNMRLDRPGS 639 K+S++ + + SF + S + + + D +R R P Sbjct: 12 VGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTVRLQLWDTAGQER-FRSLIPSY 70 Query: 640 VQASRLAGVLIGTLNQMSF--------DLFMSHGRDVNNLLYLSWGDWMEKWKLYGDEGE 691 ++ S +A V+ N SF D+ G DV +L + D +K ++ +EGE Sbjct: 71 IRDSTVAVVVYDITNVNSFQQTTKWIDDVRTERGSDVIIMLVGNKTDLADKRQVSIEEGE 130 >4K0R-A nrPDB Length = 617 Score = 34.3 bits (77), Expect = 0.24, Method: Composition-based stats. Identities = 39/192 (20%), Positives = 70/192 (36%), Gaps = 32/192 (16%) Query: 166 NTLACVVALRSWNLFPHQCNKGITFFRENIGKLEDENDEHMPIGFEV---------AFPS 216 +T+ CV L W GI +R + LED + + + FP Sbjct: 29 DTIRCVYILDPWFAGSSNV--GINRWRFLLQCLEDLDANLRKLNSRLFVIRGQPADVFPR 86 Query: 217 LLEIARGINIDVPYDS-PVLKDIYAKKELKLTRIPKEIMHKIPTTLLHSLEGMRDLDWEK 275 L + + + YDS P K +++ + ++ E ++ + H+L D +K Sbjct: 87 LFKEWNITKLSIEYDSEPFGK----ERDAAIKKLATEAGVEVIVRISHTL-----YDLDK 137 Query: 276 LLKLQSQDGSFLFSPSSTAFAFMQTRDSNCLEYLRNAVKRFNGGV--PNVFPV-DLFEHI 332 +++L P T + QT S +E L V + P+ D + Sbjct: 138 IIELNGG------QPPLT-YKRFQTLVSK-MEPLEMPADTITSDVIGKCMTPLSDDHDEK 189 Query: 333 WIVDRLQRLGIS 344 + V L+ LG Sbjct: 190 YGVPSLEELGFD 201 >2GLX-A nrPDB Length = 332 Score = 32.4 bits (72), Expect = 0.80, Method: Composition-based stats. Identities = 11/71 (15%), Positives = 25/71 (35%), Gaps = 18/71 (25%) Query: 439 ILKNAKEF------------SYNYLLEKREREELID---KWIIMKDLPGEIGFALEIPWY 483 L++A+E + ++L + D + I + + + A+ +P + Sbjct: 98 TLEDAREMVVAAREAGVVLGTNHHLRNAAAHRAMRDAIAEGRIGRPIAARVFHAVYLPPH 157 Query: 484 ---ASLPRVET 491 L R E Sbjct: 158 LQGWRLERPEA 168 >4Z2M-B nrPDB Length = 287 Score = 32.0 bits (71), Expect = 1.1, Method: Composition-based stats. Identities = 18/70 (25%), Positives = 30/70 (42%), Gaps = 4/70 (5%) Query: 230 YDSPVLKDIYAKKELKLTRIPKEIMHKIPTTL----LHSLEGMRDLDWEKLLKLQSQDGS 285 +D ++ Y+KK + IP + I L L EG++ L+W K++K D Sbjct: 212 FDMVIVYKDYSKKVTMINAIPVASLDPIKEWLNSCDLKYTEGVQSLNWTKIMKTIVDDPE 271 Query: 286 FLFSPSSTAF 295 F +F Sbjct: 272 GFFEQGGWSF 281 >3K1D-A nrPDB Length = 722 Score = 31.6 bits (70), Expect = 1.5, Method: Composition-based stats. Identities = 14/54 (25%), Positives = 23/54 (42%), Gaps = 5/54 (9%) Query: 73 EWQQLQGEDAPQISVGSNSNAFKEAVKSVKTILRN---LTDGEITISAYDTAWV 123 EW + +G D Q+ SN + V+ + I R L + T Y +W+ Sbjct: 574 EWSEQRGLDWFQLDENGFSNGIQRLVRDINDIYRCHPALWSLDTTPEGY--SWI 625 >1D5C-A nrPDB Length = 162 Score = 31.6 bits (70), Expect = 1.5, Method: Composition-based stats. Identities = 25/120 (20%), Positives = 44/120 (36%), Gaps = 14/120 (11%) Query: 584 VWAKSSVLVKAISSSFGESSDSRR--SFSDQFHEYIANARR---SDHHFNDRNMRLDRPG 638 K+S++ + + +F + S F + R D +R R P Sbjct: 11 AVGKTSIITRFMYDTFDNNYQSTIGIDFLSKTLYLDEGPVRLQLWDTAGQER-FRSLIPS 69 Query: 639 SVQASRLAGVLIGTLNQMSF--------DLFMSHGRDVNNLLYLSWGDWMEKWKLYGDEG 690 ++ S A V+ N+ SF D+ G+DV L + D + K+ +EG Sbjct: 70 YIRDSAAAIVVYDITNRQSFENTTKWIQDILNERGKDVIIALVGNKTDLGDLRKVTYEEG 129 >1VZO-A nrPDB Length = 355 Score = 30.8 bits (68), Expect = 2.5, Method: Composition-based stats. Identities = 21/97 (21%), Positives = 35/97 (36%), Gaps = 10/97 (10%) Query: 271 LDWEKLLKLQSQDGSFLFSPSSTAFAFMQTRDSNCLEYLRNAVKRFNGGVPNVFPV---D 327 +DW L G ++ + A F + N + + + P D Sbjct: 243 VDWWSL-------GVLMYELLTGASPFTVDGEKNSQAEISRRILKSEPPYPQEMSALAKD 295 Query: 328 LFEHIWIVDRLQRLGISRYFEEEIKECLDYVHRYWTD 364 L + + + D +RLG +EIKE L + W D Sbjct: 296 LIQRLLMKDPKKRLGCGPRDADEIKEHLFFQKINWDD 332 >1UMP-A nrPDB Length = 631 Score = 30.5 bits (67), Expect = 3.3, Method: Composition-based stats. Identities = 18/53 (33%), Positives = 25/53 (47%), Gaps = 5/53 (9%) Query: 108 LTDGEITISAYDTAW--VALIDAG-DKTPAFPSAVKWIAENQLSDGSWGDAYL 157 G T S TAW +ALI G ++ A V+++ E Q DG W + Y Sbjct: 546 AGKGASTPS--QTAWALMALIAGGRAESEAARRGVQYLVETQRPDGGWDEPYY 596 Score = 30.1 bits (66), Expect = 4.2, Method: Composition-based stats. Identities = 8/25 (32%), Positives = 14/25 (56%) Query: 130 DKTPAFPSAVKWIAENQLSDGSWGD 154 + P A+ W+ ++Q DG WG+ Sbjct: 511 TREPYIQKALDWVEQHQNPDGGWGE 535 Score = 29.7 bits (65), Expect = 4.7, Method: Composition-based stats. Identities = 9/17 (52%), Positives = 11/17 (64%) Query: 137 SAVKWIAENQLSDGSWG 153 A+ W+ E Q DGSWG Sbjct: 243 RALDWLLERQAGDGSWG 259 >5NZU-C nrPDB Length = 905 Score = 29.7 bits (65), Expect = 4.6, Method: Composition-based stats. Identities = 13/41 (31%), Positives = 22/41 (53%), Gaps = 2/41 (4%) Query: 181 PHQCNKGITFFRENIGKLEDENDEHM--PIGFEVAFPSLLE 219 P Q ++ + +REN+ K+ + E + P +E FP L E Sbjct: 763 PSQVSRVVKLWRENLSKVNQKAAESLADPTEYENLFPGLKE 803 >3KR9-A nrPDB Length = 225 Score = 29.7 bits (65), Expect = 4.8, Method: Composition-based stats. Identities = 10/55 (18%), Positives = 19/55 (34%) Query: 436 REEILKNAKEFSYNYLLEKREREELIDKWIIMKDLPGEIGFALEIPWYASLPRVE 490 E IL+ A +F ++E + + L E+ W ++E Sbjct: 139 AESILEEAGKFYEILVVEAGQMKLSASDVRFGPFLSKEVSPVFVQKWQKEAEKLE 193 >4N0I-A nrPDB Length = 464 Score = 29.3 bits (64), Expect = 7.0, Method: Composition-based stats. Identities = 14/44 (31%), Positives = 25/44 (56%), Gaps = 1/44 (2%) Query: 194 NIGKLEDENDEHMPIGFEVAFPSLLEIARGINIDV-PYDSPVLK 236 +G +++ + E MPIGF + SLLE + +++ P P +K Sbjct: 236 KVGIVKEFSHESMPIGFHRLYLSLLEKLINLGLEIYPVSIPSVK 279 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.315 0.130 0.365 Lambda K H 0.267 0.0399 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 31,589,848 Number of Sequences: 36641 Number of extensions: 1293605 Number of successful extensions: 3793 Number of sequences better than 10.0: 34 Number of HSP's better than 10.0 without gapping: 35 Number of HSP's successfully gapped in prelim test: 30 Number of HSP's that attempted gapping in prelim test: 3572 Number of HSP's gapped (non-prelim): 76 length of query: 802 length of database: 10,336,785 effective HSP length: 105 effective length of query: 697 effective length of database: 6,489,480 effective search space: 4523167560 effective search space used: 4523167560 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 63 (28.9 bits)