BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q25519 (695 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 3HHS-A nrPDB 1454 0.0 3HHS-B nrPDB 678 0.0 1NOL-A nrPDB 438 e-123 3IXV-A nrPDB 426 e-119 1HC1-A nrPDB 256 2e-68 3GWJ-A nrPDB 164 1e-40 4BIK-A nrPDB 36 0.055 5IMW-A nrPDB 36 0.056 1PE9-A nrPDB 31 2.2 4M0G-A nrPDB 29 6.8 >3HHS-A nrPDB Length = 694 Score = 1454 bits (3764), Expect = 0.0, Method: Compositional matrix adjust. Identities = 694/694 (100%), Positives = 694/694 (100%) Query: 2 ADIFDSFELLYDRPGEPMINTKGEDKVLFELTEQFLTPEYANNGLELNNRFGDEEEVSRK 61 ADIFDSFELLYDRPGEPMINTKGEDKVLFELTEQFLTPEYANNGLELNNRFGDEEEVSRK Sbjct: 1 ADIFDSFELLYDRPGEPMINTKGEDKVLFELTEQFLTPEYANNGLELNNRFGDEEEVSRK 60 Query: 62 IILKNLDKIPEFPKAKQLPNDADFSLFLPSHQEMANEVIDVLMSVTENQLQELLSTCVYA 121 IILKNLDKIPEFPKAKQLPNDADFSLFLPSHQEMANEVIDVLMSVTENQLQELLSTCVYA Sbjct: 61 IILKNLDKIPEFPKAKQLPNDADFSLFLPSHQEMANEVIDVLMSVTENQLQELLSTCVYA 120 Query: 122 RINLNPQLFNYCYTVAIMHRRDTGKVRVQNYAEIFPAKFLDSQVFTQAREAAAVIPKTIP 181 RINLNPQLFNYCYTVAIMHRRDTGKVRVQNYAEIFPAKFLDSQVFTQAREAAAVIPKTIP Sbjct: 121 RINLNPQLFNYCYTVAIMHRRDTGKVRVQNYAEIFPAKFLDSQVFTQAREAAAVIPKTIP 180 Query: 182 RTPIIIPRDYTATDLEEEHRLAYWREDLGINLHHWHWHLVYPFSASDEKIVAKDRRGELF 241 RTPIIIPRDYTATDLEEEHRLAYWREDLGINLHHWHWHLVYPFSASDEKIVAKDRRGELF Sbjct: 181 RTPIIIPRDYTATDLEEEHRLAYWREDLGINLHHWHWHLVYPFSASDEKIVAKDRRGELF 240 Query: 242 FYMHQQIIARYNCERLCNSLKRVKKFSDWREPIPEAYYPKLDSLTSARGWPPRQAGMRWQ 301 FYMHQQIIARYNCERLCNSLKRVKKFSDWREPIPEAYYPKLDSLTSARGWPPRQAGMRWQ Sbjct: 241 FYMHQQIIARYNCERLCNSLKRVKKFSDWREPIPEAYYPKLDSLTSARGWPPRQAGMRWQ 300 Query: 302 DLKRPVDGLNVTIDDMERYRRNIEEAIATGNVILPDKSTKKLDIDMLGNMMEASVLSPNR 361 DLKRPVDGLNVTIDDMERYRRNIEEAIATGNVILPDKSTKKLDIDMLGNMMEASVLSPNR Sbjct: 301 DLKRPVDGLNVTIDDMERYRRNIEEAIATGNVILPDKSTKKLDIDMLGNMMEASVLSPNR 360 Query: 362 DLYGSIHNNMHSFSAYMHDPEHRYLESFGVIADEATTMRDPFFYRVHAWVDDIFQSFKEA 421 DLYGSIHNNMHSFSAYMHDPEHRYLESFGVIADEATTMRDPFFYRVHAWVDDIFQSFKEA Sbjct: 361 DLYGSIHNNMHSFSAYMHDPEHRYLESFGVIADEATTMRDPFFYRVHAWVDDIFQSFKEA 420 Query: 422 PHNVRPYSRSQLENPGVQVTSVAVESAGGQQNVLNTFWMQSDVNLSKGLDFSDRGPVYAR 481 PHNVRPYSRSQLENPGVQVTSVAVESAGGQQNVLNTFWMQSDVNLSKGLDFSDRGPVYAR Sbjct: 421 PHNVRPYSRSQLENPGVQVTSVAVESAGGQQNVLNTFWMQSDVNLSKGLDFSDRGPVYAR 480 Query: 482 FTHLNHRPFRYVIKANNTASARRTTVRIFIAPKTDERNLPWALSDQRKMFIEMDRFVVPL 541 FTHLNHRPFRYVIKANNTASARRTTVRIFIAPKTDERNLPWALSDQRKMFIEMDRFVVPL Sbjct: 481 FTHLNHRPFRYVIKANNTASARRTTVRIFIAPKTDERNLPWALSDQRKMFIEMDRFVVPL 540 Query: 542 SAGENTITRQSTESSLTIPFEQTFRDLSIQGSDPRRSELAAFNYCGCGWPQHMLVPKGTV 601 SAGENTITRQSTESSLTIPFEQTFRDLSIQGSDPRRSELAAFNYCGCGWPQHMLVPKGTV Sbjct: 541 SAGENTITRQSTESSLTIPFEQTFRDLSIQGSDPRRSELAAFNYCGCGWPQHMLVPKGTV 600 Query: 602 GGVAYQLFVMLSNYELDKIEQPDGRELSCVEASMFCGLKDKKYPDARPMGYPFDRPSNSA 661 GGVAYQLFVMLSNYELDKIEQPDGRELSCVEASMFCGLKDKKYPDARPMGYPFDRPSNSA Sbjct: 601 GGVAYQLFVMLSNYELDKIEQPDGRELSCVEASMFCGLKDKKYPDARPMGYPFDRPSNSA 660 Query: 662 TNIEDFSAMSNMGLQDIVIKLSDVTEPNPRNPPA 695 TNIEDFSAMSNMGLQDIVIKLSDVTEPNPRNPPA Sbjct: 661 TNIEDFSAMSNMGLQDIVIKLSDVTEPNPRNPPA 694 >3HHS-B nrPDB Length = 684 Score = 678 bits (1749), Expect = 0.0, Method: Compositional matrix adjust. Identities = 333/682 (48%), Positives = 459/682 (67%), Gaps = 20/682 (2%) Query: 11 LYDRPGEPMINTKGEDKVLFELTEQFLTPEYANNGLELNNRFGDEEEVSRKIILKNLDKI 70 +DRP EP KGEDKV+FE+ + + +Y + L+NRFG+E +++I ++N+ + Sbjct: 10 FFDRPNEPCFMQKGEDKVVFEIPDHYYPDKYKSLSNTLSNRFGNE--ATKRIPIRNI-TL 66 Query: 71 PEFPKAKQLPNDADFSLFLPSHQEMANEVIDVLMSVTENQLQELLSTCVYARINLNPQLF 130 P QLP + FSLF+P H+ MA ++ID+ M + + +++L S C Y ++ +NP +F Sbjct: 67 PNLEVPMQLPYNDQFSLFVPKHRTMAAKLIDIFMGMRD--VEDLQSVCSYCQLRINPYMF 124 Query: 131 NYCYTVAIMHRRDTGKVRVQNYAEIFPAKFLDSQVFTQAREAAAVIPKTIPRTPIIIPRD 190 NYC +VAI+HR DT + + +AE FP KF+DS+VF +ARE + V+ + R P+ +P + Sbjct: 125 NYCLSVAILHRPDTKGLSIPTFAETFPDKFMDSKVFLRAREVSNVV-ISGSRMPVNVPIN 183 Query: 191 YTATDLEEEHRLAYWREDLGINLHHWHWHLVYPFSASDEKIVAKDRRGELFFYMHQQIIA 250 YTA E E R+AY+RED+GINLHHWHWHLVYPF ++D IV KDRRGELF+YMHQQII Sbjct: 184 YTANTTEPEQRVAYFREDIGINLHHWHWHLVYPFDSADRSIVNKDRRGELFYYMHQQIIG 243 Query: 251 RYNCERLCNSLKRVKKFSDWREPIPEAYYPKLDSLTSARGWPPRQAGMRWQDLKRPVDGL 310 RYN ER+CN L +VK FSD+ PI E Y+PKLDS ++R WPPR AG +++L R VD + Sbjct: 244 RYNVERMCNGLPQVKPFSDFSAPIEEGYFPKLDSQVASRTWPPRFAGSVFRNLDRTVDQV 303 Query: 311 NVTIDDMERYRRNIEEAIATGNVILPDKSTKKLD----IDMLGNMMEASVLSPNRDLYGS 366 + + + +R EAI + +P+ LD IDMLGN+ME+S++SPNR YG Sbjct: 304 KIDVRKLFTWRDQFLEAIQKMAIKMPNGRELPLDEVTGIDMLGNLMESSIISPNRGYYGD 363 Query: 367 IHNNMHSFSAYMHDPEHRYLESFGVIADEATTMRDPFFYRVHAWVDDIFQSFKEAPHNVR 426 +HN H F+AY HDP+HR+LE FGV+ D AT MRDPFFYR H +VDD+F +KE + Sbjct: 364 LHNMGHVFAAYTHDPDHRHLEQFGVMGDSATAMRDPFFYRWHRFVDDVFNIYKE---KLT 420 Query: 427 PYSRSQLENPGVQVTSVAVESAGGQQNVLNTFWMQSDVNLSKGLDFSDRGPVYARFTHLN 486 PY+ +L+ PGV+V+SV +E G + N L T W QS V L +GLDF+ RG V ARFTHL Sbjct: 421 PYTNERLDFPGVRVSSVGIE--GARPNTLRTLWQQSTVELGRGLDFTPRGSVLARFTHLQ 478 Query: 487 HRPFRYVIKANNTASAR-RTTVRIFIAPKTDERNLPWALSDQRKMFIEMDRFVVPLSAGE 545 H F+YVI+ NNT TVRIF+APK D+ P + + QR++ IE+D+F L G Sbjct: 479 HDEFQYVIEVNNTTGGNLMGTVRIFMAPKVDDNGQPMSFNKQRRLMIELDKFSQALRPGT 538 Query: 546 NTITRQSTESSLTIPFEQTFRDLSIQGSDPRRSELAAFNYCGCGWPQHMLVPKGTVGGVA 605 NTI R+S +SS+TIP+E+TFR+ S + DP + A F++CGCGWP HML+PKGT G Sbjct: 539 NTIRRRSVDSSVTIPYERTFRNQSERPGDPGTAGAAEFDFCGCGWPHHMLIPKGTAQGYP 598 Query: 606 YQLFVMLSNYELDKIEQPDGRELSCVEASMFCGLKDKKYPDARPMGYPFDRP-SNSATNI 664 LFVM+SN+ D+IEQ SC +A+ +CG++D+KYPD + MGYPFDR +N A + Sbjct: 599 VVLFVMISNWNNDRIEQ--DLVGSCNDAASYCGIRDRKYPDKQAMGYPFDRKMANDAATL 656 Query: 665 EDFSAMSNMGLQDIVIKLSDVT 686 DF NM ++D I+ SD T Sbjct: 657 SDF-LRPNMAVRDCSIQFSDTT 677 >1NOL-A nrPDB Length = 628 Score = 438 bits (1127), Expect = e-123, Method: Compositional matrix adjust. Identities = 250/641 (39%), Positives = 373/641 (58%), Gaps = 38/641 (5%) Query: 56 EEVSRKIILKNLDKIPEFPKAK---QLPNDADFSLFLPSHQEMANEVIDVLMSVTENQLQ 112 E++S ++ + DK + K +L A FS F P H E A + +V + Sbjct: 14 EQLSSATVIGDGDKHKHSDRLKNVGKLQPGAIFSCFHPDHLEEARHLYEVFWEAGD--FN 71 Query: 113 ELLSTCVYARINLNPQLFNYCYTVAIMHRRDTGKVRVQNYAEIFPAKFLDSQVFTQAREA 172 + + AR +N LF + VA++HR D + V EIFP KF+ S +A + Sbjct: 72 DFIEIAKEARTFVNEGLFAFAAEVAVLHRDDCKGLYVPPVQEIFPDKFIPSAAINEAFKK 131 Query: 173 AAVIPKTIPRTPIIIPRDYTATDLEEEHRLAYWREDLGINLHHWHWHLVYPFSASDEKIV 232 A V P+ +PI++ T L+ E+RLAY+RED+GIN HHWHWHLVYP S + K Sbjct: 132 AHVRPE-FDESPILVDVQDTGNILDPEYRLAYYREDVGINAHHWHWHLVYP-STWNPKYF 189 Query: 233 AK--DRRGELFFYMHQQIIARYNCERLCNSLKRVKKFSDWREPIPEAYYPKLDSLTSARG 290 K DR+GELF+YMHQQ+ ARY+CERL N + R+ F+++ EP+ Y P L + S + Sbjct: 190 GKKKDRKGELFYYMHQQMCARYDCERLSNGMHRMLPFNNFDEPLA-GYAPHLTHVASGKY 248 Query: 291 WPPRQAGMRWQDLKRPVDGLNVTIDDMERYRRNIEEAIATGNVILPDKSTKKLD----ID 346 + PR G++ +DL ++ I +M R R I ++I G VI D S K LD D Sbjct: 249 YSPRPDGLKLRDLG------DIEISEMVRMRERILDSIHLGYVISEDGSHKTLDELHGTD 302 Query: 347 MLGNMMEASVLSPNRDLYGSIHNNMHSFSAYMHDPEHRYLESFGVIADEATTMRDPFFYR 406 +LG ++E+S S N + YG++HN H A +HDP+ R+ E GV++D +T++RDP FY Sbjct: 303 ILGALVESSYESVNHEYYGNLHNWGHVTMARIHDPDGRFHEEPGVMSDTSTSLRDPIFYN 362 Query: 407 VHAWVDDIFQSFKEAPHNVRPYSRSQLENPGVQVTSVAVESAGGQQNVLNTFWMQSDVNL 466 H ++D+IF +K ++PY L P +QV V + + NV++TF + ++ L Sbjct: 363 WHRFIDNIFHEYKNT---LKPYDHDVLNFPDIQVQDVTLHAR--VDNVVHTFMREQELEL 417 Query: 467 SKGLDFSDRGPVYARFTHLNHRPFRYVIKA-NNTASARRTTVRIFIAPKTDERNLPWALS 525 G++ + + AR+ HL+H PF Y + NN+AS + TVRIF+APK DE Sbjct: 418 KHGINPGNARSIKARYYHLDHEPFSYAVNVQNNSASDKHATVRIFLAPKYDELGNEIKAD 477 Query: 526 DQRKMFIEMDRFVVPLSAGENTITRQSTESSLTIPFEQTFRD-LSIQGSDPRRSELAAFN 584 + R+ IE+D+F L G+NT+ R S +SS+T+ + TF D L G + +SE Sbjct: 478 ELRRTAIELDKFKTDLHPGKNTVVRHSLDSSVTLSHQPTFEDLLHGVGLNEHKSE----- 532 Query: 585 YCGCGWPQHMLVPKGTVGGVAYQLFVMLSNYELDKIEQPDGRE-LSCVEASMFCGLKDKK 643 YC CGWP H+LVPKG + G+ Y LFVML++++ DK+ DG E ++CV+A +CG +D K Sbjct: 533 YCSCGWPSHLLVPKGNIKGMEYHLFVMLTDWDKDKV---DGSESVACVDAVSYCGARDHK 589 Query: 644 YPDARPMGYPFDRPSNSATNIEDFSAMSNMGLQDIVIKLSD 684 YPD +PMG+PFDRP ++ +I DF +NM ++DI IK + Sbjct: 590 YPDKKPMGFPFDRPIHTE-HISDF-LTNNMFIKDIKIKFHE 628 >3IXV-A nrPDB Length = 626 Score = 426 bits (1095), Expect = e-119, Method: Compositional matrix adjust. Identities = 235/610 (38%), Positives = 358/610 (58%), Gaps = 30/610 (4%) Query: 79 LPNDADFSLFLPSHQEMANEVIDVLMSVTENQLQELLSTCVYARINLNPQLFNYCYTVAI 138 LP FS F H A E+ L + + + C AR +N +F Y +VA+ Sbjct: 39 LPRGTLFSCFHARHLAEATELYVALYGAKD--FNDFIHLCEQARQIVNEGMFVYAVSVAV 96 Query: 139 MHRRDTGKVRVQNYAEIFPAKFLDSQVFTQAREAAAVIPKTIPRTPIIIPRDYTATDLEE 198 +HR D + V E+FP +F+ ++ +A + A+ P + I++ + T L+ Sbjct: 97 LHREDCKGITVPPIQEVFPDRFVPAETINRANKEASNHPD---QQSIVVEAEETGNILDP 153 Query: 199 EHRLAYWREDLGINLHHWHWHLVYPFSASDEKIVA-KDRRGELFFYMHQQIIARYNCERL 257 E++L+Y+RED+GIN HHWHWH+VYP + + + KDR+GELFFYMHQQ+ ARY+ ERL Sbjct: 154 EYKLSYFREDIGINAHHWHWHIVYPATWNPTVMGKEKDRKGELFFYMHQQMCARYDSERL 213 Query: 258 CNSLKRVKKFSDWREPIPEAYYPKLDSLTSARGWPPRQAGMRWQDLKRPVDGLNVTIDDM 317 N L+R+ F ++ EP+ E Y P L SL S + R G DL +V + DM Sbjct: 214 SNGLQRMIPFHNFDEPL-EGYAPHLTSLVSGLQYASRPEGYSIHDLS------DVDVQDM 266 Query: 318 ERYRRNIEEAIATGNVILPDKSTKKLDI----DMLGNMMEASVLSPNRDLYGSIHNNMHS 373 R+R I +AI ++ D + LDI D+LG+++E+S S N + YGS+HN H Sbjct: 267 VRWRERILDAINMHYIVDKDNNKIPLDIEHGTDILGDIIESSDESKNVEYYGSLHNWGHV 326 Query: 374 FSAYMHDPEHRYLESFGVIADEATTMRDPFFYRVHAWVDDIFQSFKEAPHNVRPYSRSQL 433 A + DP+HR+ E+ GV++D +T++RDP FYR H ++D+IFQ K++ H PY++ +L Sbjct: 327 MMANITDPDHRFQENPGVMSDTSTSLRDPIFYRWHRFIDNIFQEHKKSFH---PYTKEEL 383 Query: 434 ENPGVQVTSVAVESAGGQQNVLNTFWMQSDVNLSKGLDFSDRGPVYARFTHLNHRPFRY- 492 PGV+V V++ S NV+ T +S + LS G++F V ++ HL+H PF Y Sbjct: 384 SFPGVEVVGVSINSKTA--NVITTLIKESLLELSHGINFGTDQSVKVKYHHLDHEPFTYN 441 Query: 493 VIKANNTASARRTTVRIFIAPKTDERNLPWALSDQRKMFIEMDRFVVPLSAGENTITRQS 552 ++ NN+ + + +TVRIF+APK DE N +QR++FIE+D+F L+ G+NTI R Sbjct: 442 IVVENNSGAEKHSTVRIFLAPKYDELNNKLEPDEQRRLFIELDKFFYTLTPGKNTIVRNH 501 Query: 553 TESSLTIPFEQTFRDLSIQGSDPRRSELAAFNYCGCGWPQHMLVPKGTVGGVAYQLFVML 612 +SS+TI +TF L G+ SE + YC CGWP+HML+P+G+ G+ ++LFVML Sbjct: 502 QDSSVTISKVRTFDQL---GAGEGVSEDST-EYCSCGWPEHMLIPRGSHKGMEFELFVML 557 Query: 613 SNYELDKIEQPDGRELSCVEASMFCGLKDKKYPDARPMGYPFDRPSNSATNIEDFSAMSN 672 ++++ D + + C +A +CG +D +YPD + MG+PFDR + T E + N Sbjct: 558 TDHDEDTVAGLSENAV-CSDAVSYCGARDDRYPDKKAMGFPFDRKIEARTAAEFLTP--N 614 Query: 673 MGLQDIVIKL 682 MGL DI IK Sbjct: 615 MGLTDIKIKF 624 >1HC1-A nrPDB Length = 657 Score = 256 bits (655), Expect = 2e-68, Method: Compositional matrix adjust. Identities = 181/587 (30%), Positives = 282/587 (48%), Gaps = 45/587 (7%) Query: 85 FSLFLPSHQEMANEVIDVLMSVTENQLQE---LLSTCVYARINLNPQLFNYCYTVAIMHR 141 +SLF ++ A + VL NQ +E S Y R +N F Y V+++H Sbjct: 72 YSLFNTRQRKEALMLFAVL-----NQCKEWYCFRSNAAYFRERMNEGEFVYALYVSVIHS 126 Query: 142 RDTGKVRVQNYAEIFPAKFLDSQVFTQAREAAAVIPKTIPRTPIIIPRDYTATDLEEEHR 201 + + + +I P F +S+V +A A + + P +T T E R Sbjct: 127 KLGDGIVLPPLYQITPHMFTNSEVIDKAYSAK------MTQKPGTFNVSFTGTKKNREQR 180 Query: 202 LAYWREDLGINLHHWHWHLVYPFSASDEKIVAKDRRGELFFYMHQQIIARYNCERLCNSL 261 +AY+ ED+G+N+HH WH+ +PF D DR+GELFF++H Q+ AR++ ERL N L Sbjct: 181 VAYFGEDIGMNIHHVTWHMDFPFWWEDSYGYHLDRKGELFFWVHHQLTARFDFERLSNWL 240 Query: 262 KRVKKFSDWREPIPEAYYPKLDSLTSARGWPPRQAGMRWQDLKRPVDGLNVTIDDMERYR 321 V + W I E + P L S +P R + ++D VDG+ + D+E Sbjct: 241 DPVDELH-WDRIIREGFAP-LTSYKYGGEFPVRPDNIHFED----VDGV-AHVHDLEITE 293 Query: 322 RNIEEAIATGNVILPDKSTKKL----DIDMLGNMMEASVLSPNRDLYGSIHNNMHSFSAY 377 I EAI G + D T + I++LG+++E+S S N YGS+HN H Sbjct: 294 SRIHEAIDHGYITDSDGHTIDIRQPKGIELLGDIIESSKYSSNVQYYGSLHNTAHVMLGR 353 Query: 378 MHDPEHRYLESFGVIADEATTMRDPFFYRVHAWVDDIFQSFKEAPHNVRPYSRSQLENPG 437 DP ++ GV+ T RDP F+R+H ++D+IF+ ++ PY+ LE G Sbjct: 354 QGDPHGKFNLPPGVMEHFETATRDPSFFRLHKYMDNIFKKHTDS---FPPYTHDNLEFSG 410 Query: 438 VQVTSVAVESAGGQQNVLNTFWMQSDVNLSKGLDFSDR---GPVYARFTHLNHRPFRYVI 494 + V VA++ L TF+ + +L +D + + AR LNH F Y I Sbjct: 411 MVVNGVAIDGE------LITFFDEFQYSLINAVDSGENIEDVEINARVHRLNHNEFTYKI 464 Query: 495 K-ANNTASARRTTVRIFIAPKTDERNLPWALSDQRKMFIEMDRFVVPLSAGENTITRQST 553 +NN R T RIF+ P D + L + R IE+D+F + +G TI R S Sbjct: 465 TMSNNNDGERLATFRIFLCPIEDNNGITLTLDEARWFCIELDKFFQKVPSGPETIERSSK 524 Query: 554 ESSLTIPFEQTFRDLSIQGSDPRRS----ELAAFNYCGCGWPQHMLVPKGTVGGVAYQLF 609 +SS+T+P +F+ L Q + +L+A+ CG P ML+PK G+ + L+ Sbjct: 525 DSSVTVPDMPSFQSLKEQADNAVNGGHDLDLSAYERS-CGIPDRMLLPKSKPEGMEFNLY 583 Query: 610 VMLSNYELDKIEQPDGRELSCVEASMFCGLKDKKYPDARPMGYPFDR 656 V +++ + D G + A CG+ + YPD RP+GYP +R Sbjct: 584 VAVTDGDKDTEGHNGGHDYGGTHAQ--CGVHGEAYPDNRPLGYPLER 628 >3GWJ-A nrPDB Length = 674 Score = 164 bits (414), Expect = 1e-40, Method: Compositional matrix adjust. Identities = 160/619 (25%), Positives = 271/619 (43%), Gaps = 82/619 (13%) Query: 79 LPNDADFSLFLPSHQEMANEVIDVL-MSVTENQLQELLSTCVYARINLNPQLFNYCYTVA 137 LP +FS+F H ++ +E I + + + +AR++LN F Y Y +A Sbjct: 69 LPKYNEFSVF---HDKLRDEAIALFHLFYYAKDFDTFYKSAAFARVHLNQGQFLYAYYIA 125 Query: 138 IMHRRDTGKVRVQNYAEIFPAKFLD----SQVFTQAREAAAVIPKTIPRTPIIIPRDYTA 193 I+ R+DT + + EI+P F++ ++F + + P+ I+ ++ Sbjct: 126 IIQRKDTYGIVLPAPYEIYPELFVNIDTTYKMFRTKMQNGLINPEAAVEYGIVKEDNHYV 185 Query: 194 ---------TDLEEEHRLAYWREDLGINLHHWHWHLVYPFSASDEKIV-AKDRRGELFFY 243 T EE RLAY+ ED+G+N +++ +H+ PF + EK K+RRGE++ Y Sbjct: 186 YYSNYSNAITYYNEEQRLAYFTEDIGLNAYYFFFHIHLPFWWTAEKYGNLKERRGEMYHY 245 Query: 244 MHQQIIARYNCERLCNSLKRVKKFSDWREPIPEAYYPKLDSLTSARGWPPRQAGMRWQDL 303 + Q++ RY ERL N L + +FS W P+ +YP L S + P + ++ Sbjct: 246 FYDQLLTRYYFERLTNGLGTIPEFS-WYSPVKTGHYPLLTSYYTPFSQRPNFYNVHSEEN 304 Query: 304 KRPVDGLNVTIDDMERYRRNIEEAIATGNVILPDKSTKKLDIDMLGNMMEASVLSPNRDL 363 + L+ Y +A+ G V T L+ D N + N DL Sbjct: 305 YEKIRFLDA-------YENYFVQALQKG-VFEGFGQTIYLN-DSKANSFVGNYWQDNADL 355 Query: 364 YGS--IHNNMHSFSAYMHD-------PEHRYLESFGVIADEATTMRDPFFYRVHAWVDDI 414 YG + S+ P +Y + T++RDP FY+++ + Sbjct: 356 YGEEVTKDYQRSYEIVARQVLGAAPKPFDKYTFMPSALDFYQTSLRDPTFYQLYNRIIGY 415 Query: 415 FQSFKEAPHNVRPYSRSQLENPGVQVTSVAVESAGGQQNVLNTFWMQSDVNLSKGLDFSD 474 F FK+ + P+S+ +L GV+V +V V+ L TF+ D + + + F Sbjct: 416 FNQFKQY---LEPHSQEKLHFVGVKVNNVVVDK-------LVTFFEYYDFDATNTV-FLT 464 Query: 475 RGPVYARFTH--------LNHRPFRYVIKANNTASARRTTVRIFIAPKTDERNLPWALSD 526 + ++ H LNH+PF I A V+IF+ PK +E P L + Sbjct: 465 EEELKTKYPHNLKVRQPRLNHQPFNINIDIKADV-ATDAVVKIFMGPKYNENGFPITLEN 523 Query: 527 QRKMFIEMDRFVVPLSAGENTITRQSTESSL----TIPFEQTFRDLSIQGSDPRRSELAA 582 F EMD F ++ G+NTI R S E + ++P + ++ L +G P Sbjct: 524 DWMKFFEMDWFTHKITPGQNTIVRNSNEFVIFKEDSLPSTELYKLLE-KGKVPFDMS-ED 581 Query: 583 FNYCGCGWPQHMLVPKGTVGGVAYQLFVMLSNYELDKIEQPDGRELSCVEASMFCGLKDK 642 F Y P+ +++P+GT GG +Q V + +E + L+ E M Sbjct: 582 FGYL----PKRLMLPRGTKGGFPFQFVVFVYPFE------STTKNLTPYEKFMI------ 625 Query: 643 KYPDARPMGYPFDRPSNSA 661 D +P+GYPFDRP +++ Sbjct: 626 ---DNKPLGYPFDRPVDTS 641 >4BIK-A nrPDB Length = 535 Score = 36.2 bits (82), Expect = 0.055, Method: Compositional matrix adjust. Identities = 24/87 (27%), Positives = 42/87 (48%), Gaps = 7/87 (8%) Query: 487 HRPFRYVIKANNTASARRTTVRIFIAPKTDERNLPWALSDQRKMFIEMDRFVVPLSAGEN 546 HRP YV+ S T ++ ++ D+R P AL + +E ++P++ G+ Sbjct: 99 HRPGEYVVIEKKKQSISNATSKLSVSSANDDRIFPGALLKADQSLLENLPTLIPVNRGKT 158 Query: 547 TIT-----RQSTESSLTI--PFEQTFR 566 TI+ ++ ES+LT+ P T R Sbjct: 159 TISVNLPGLKNGESNLTVENPSNSTVR 185 >5IMW-A nrPDB Length = 471 Score = 36.2 bits (82), Expect = 0.056, Method: Compositional matrix adjust. Identities = 24/87 (27%), Positives = 42/87 (48%), Gaps = 7/87 (8%) Query: 487 HRPFRYVIKANNTASARRTTVRIFIAPKTDERNLPWALSDQRKMFIEMDRFVVPLSAGEN 546 HRP YV+ S T ++ ++ D+R P AL + +E ++P++ G+ Sbjct: 40 HRPGEYVVIEKKKQSISNATSKLSVSSANDDRIFPGALLKADQSLLENLPTLIPVNRGKT 99 Query: 547 TIT-----RQSTESSLTI--PFEQTFR 566 TI+ ++ ES+LT+ P T R Sbjct: 100 TISVNLPGLKNGESNLTVENPSNSTVR 126 >1PE9-A nrPDB Length = 361 Score = 30.8 bits (68), Expect = 2.2, Method: Compositional matrix adjust. Identities = 17/50 (34%), Positives = 24/50 (48%) Query: 342 KLDIDMLGNMMEASVLSPNRDLYGSIHNNMHSFSAYMHDPEHRYLESFGV 391 KL + + N+ R YGSIH+ + F DP +RY SFG+ Sbjct: 225 KLHVTLFNNVFNRVTERAPRVRYGSIHSFNNVFKGDAKDPVYRYQYSFGI 274 >4M0G-A nrPDB Length = 432 Score = 29.3 bits (64), Expect = 6.8, Method: Compositional matrix adjust. Identities = 16/61 (26%), Positives = 27/61 (44%), Gaps = 2/61 (3%) Query: 401 DPFFYRVHAWVDDI--FQSFKEAPHNVRPYSRSQLENPGVQVTSVAVESAGGQQNVLNTF 458 +P + W +DI +S E P N R Y E G+Q++ +V Q N++ Sbjct: 370 EPVCEELPGWTEDITGVRSLDELPENARKYVERVSELTGIQLSMFSVGPDRNQTNIVRNV 429 Query: 459 W 459 + Sbjct: 430 Y 430 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 3HHS-A nrPDB 1049 0.0 3HHS-B nrPDB 945 0.0 1NOL-A nrPDB 818 0.0 3IXV-A nrPDB 814 0.0 1HC1-A nrPDB 688 0.0 3GWJ-A nrPDB 576 e-165 Sequences not found previously or not previously below threshold: 6ELS-A nrPDB 42 7e-04 6HQJ-A nrPDB 39 0.010 1PE9-A nrPDB 35 0.12 4Z13-A nrPDB 35 0.12 2P3X-A nrPDB 35 0.16 4Z0Z-A nrPDB 34 0.20 5CE9-A nrPDB 33 0.37 3BSH-A nrPDB 32 0.63 5TX1-M nrPDB 32 0.99 6M9Z-A nrPDB 32 1.1 5MWC-D nrPDB 30 2.9 2WC7-A nrPDB 30 3.8 6CGV-M nrPDB 29 7.2 4HU8-A nrPDB 29 7.4 >3HHS-A nrPDB Length = 694 Score = 1049 bits (2713), Expect = 0.0, Method: Composition-based stats. Identities = 694/694 (100%), Positives = 694/694 (100%) Query: 2 ADIFDSFELLYDRPGEPMINTKGEDKVLFELTEQFLTPEYANNGLELNNRFGDEEEVSRK 61 ADIFDSFELLYDRPGEPMINTKGEDKVLFELTEQFLTPEYANNGLELNNRFGDEEEVSRK Sbjct: 1 ADIFDSFELLYDRPGEPMINTKGEDKVLFELTEQFLTPEYANNGLELNNRFGDEEEVSRK 60 Query: 62 IILKNLDKIPEFPKAKQLPNDADFSLFLPSHQEMANEVIDVLMSVTENQLQELLSTCVYA 121 IILKNLDKIPEFPKAKQLPNDADFSLFLPSHQEMANEVIDVLMSVTENQLQELLSTCVYA Sbjct: 61 IILKNLDKIPEFPKAKQLPNDADFSLFLPSHQEMANEVIDVLMSVTENQLQELLSTCVYA 120 Query: 122 RINLNPQLFNYCYTVAIMHRRDTGKVRVQNYAEIFPAKFLDSQVFTQAREAAAVIPKTIP 181 RINLNPQLFNYCYTVAIMHRRDTGKVRVQNYAEIFPAKFLDSQVFTQAREAAAVIPKTIP Sbjct: 121 RINLNPQLFNYCYTVAIMHRRDTGKVRVQNYAEIFPAKFLDSQVFTQAREAAAVIPKTIP 180 Query: 182 RTPIIIPRDYTATDLEEEHRLAYWREDLGINLHHWHWHLVYPFSASDEKIVAKDRRGELF 241 RTPIIIPRDYTATDLEEEHRLAYWREDLGINLHHWHWHLVYPFSASDEKIVAKDRRGELF Sbjct: 181 RTPIIIPRDYTATDLEEEHRLAYWREDLGINLHHWHWHLVYPFSASDEKIVAKDRRGELF 240 Query: 242 FYMHQQIIARYNCERLCNSLKRVKKFSDWREPIPEAYYPKLDSLTSARGWPPRQAGMRWQ 301 FYMHQQIIARYNCERLCNSLKRVKKFSDWREPIPEAYYPKLDSLTSARGWPPRQAGMRWQ Sbjct: 241 FYMHQQIIARYNCERLCNSLKRVKKFSDWREPIPEAYYPKLDSLTSARGWPPRQAGMRWQ 300 Query: 302 DLKRPVDGLNVTIDDMERYRRNIEEAIATGNVILPDKSTKKLDIDMLGNMMEASVLSPNR 361 DLKRPVDGLNVTIDDMERYRRNIEEAIATGNVILPDKSTKKLDIDMLGNMMEASVLSPNR Sbjct: 301 DLKRPVDGLNVTIDDMERYRRNIEEAIATGNVILPDKSTKKLDIDMLGNMMEASVLSPNR 360 Query: 362 DLYGSIHNNMHSFSAYMHDPEHRYLESFGVIADEATTMRDPFFYRVHAWVDDIFQSFKEA 421 DLYGSIHNNMHSFSAYMHDPEHRYLESFGVIADEATTMRDPFFYRVHAWVDDIFQSFKEA Sbjct: 361 DLYGSIHNNMHSFSAYMHDPEHRYLESFGVIADEATTMRDPFFYRVHAWVDDIFQSFKEA 420 Query: 422 PHNVRPYSRSQLENPGVQVTSVAVESAGGQQNVLNTFWMQSDVNLSKGLDFSDRGPVYAR 481 PHNVRPYSRSQLENPGVQVTSVAVESAGGQQNVLNTFWMQSDVNLSKGLDFSDRGPVYAR Sbjct: 421 PHNVRPYSRSQLENPGVQVTSVAVESAGGQQNVLNTFWMQSDVNLSKGLDFSDRGPVYAR 480 Query: 482 FTHLNHRPFRYVIKANNTASARRTTVRIFIAPKTDERNLPWALSDQRKMFIEMDRFVVPL 541 FTHLNHRPFRYVIKANNTASARRTTVRIFIAPKTDERNLPWALSDQRKMFIEMDRFVVPL Sbjct: 481 FTHLNHRPFRYVIKANNTASARRTTVRIFIAPKTDERNLPWALSDQRKMFIEMDRFVVPL 540 Query: 542 SAGENTITRQSTESSLTIPFEQTFRDLSIQGSDPRRSELAAFNYCGCGWPQHMLVPKGTV 601 SAGENTITRQSTESSLTIPFEQTFRDLSIQGSDPRRSELAAFNYCGCGWPQHMLVPKGTV Sbjct: 541 SAGENTITRQSTESSLTIPFEQTFRDLSIQGSDPRRSELAAFNYCGCGWPQHMLVPKGTV 600 Query: 602 GGVAYQLFVMLSNYELDKIEQPDGRELSCVEASMFCGLKDKKYPDARPMGYPFDRPSNSA 661 GGVAYQLFVMLSNYELDKIEQPDGRELSCVEASMFCGLKDKKYPDARPMGYPFDRPSNSA Sbjct: 601 GGVAYQLFVMLSNYELDKIEQPDGRELSCVEASMFCGLKDKKYPDARPMGYPFDRPSNSA 660 Query: 662 TNIEDFSAMSNMGLQDIVIKLSDVTEPNPRNPPA 695 TNIEDFSAMSNMGLQDIVIKLSDVTEPNPRNPPA Sbjct: 661 TNIEDFSAMSNMGLQDIVIKLSDVTEPNPRNPPA 694 >3HHS-B nrPDB Length = 684 Score = 945 bits (2442), Expect = 0.0, Method: Composition-based stats. Identities = 333/682 (48%), Positives = 459/682 (67%), Gaps = 20/682 (2%) Query: 11 LYDRPGEPMINTKGEDKVLFELTEQFLTPEYANNGLELNNRFGDEEEVSRKIILKNLDKI 70 +DRP EP KGEDKV+FE+ + + +Y + L+NRFG+E +++I ++N+ + Sbjct: 10 FFDRPNEPCFMQKGEDKVVFEIPDHYYPDKYKSLSNTLSNRFGNE--ATKRIPIRNI-TL 66 Query: 71 PEFPKAKQLPNDADFSLFLPSHQEMANEVIDVLMSVTENQLQELLSTCVYARINLNPQLF 130 P QLP + FSLF+P H+ MA ++ID+ M + + +++L S C Y ++ +NP +F Sbjct: 67 PNLEVPMQLPYNDQFSLFVPKHRTMAAKLIDIFMGMRD--VEDLQSVCSYCQLRINPYMF 124 Query: 131 NYCYTVAIMHRRDTGKVRVQNYAEIFPAKFLDSQVFTQAREAAAVIPKTIPRTPIIIPRD 190 NYC +VAI+HR DT + + +AE FP KF+DS+VF +ARE + V+ + R P+ +P + Sbjct: 125 NYCLSVAILHRPDTKGLSIPTFAETFPDKFMDSKVFLRAREVSNVV-ISGSRMPVNVPIN 183 Query: 191 YTATDLEEEHRLAYWREDLGINLHHWHWHLVYPFSASDEKIVAKDRRGELFFYMHQQIIA 250 YTA E E R+AY+RED+GINLHHWHWHLVYPF ++D IV KDRRGELF+YMHQQII Sbjct: 184 YTANTTEPEQRVAYFREDIGINLHHWHWHLVYPFDSADRSIVNKDRRGELFYYMHQQIIG 243 Query: 251 RYNCERLCNSLKRVKKFSDWREPIPEAYYPKLDSLTSARGWPPRQAGMRWQDLKRPVDGL 310 RYN ER+CN L +VK FSD+ PI E Y+PKLDS ++R WPPR AG +++L R VD + Sbjct: 244 RYNVERMCNGLPQVKPFSDFSAPIEEGYFPKLDSQVASRTWPPRFAGSVFRNLDRTVDQV 303 Query: 311 NVTIDDMERYRRNIEEAIATGNVILPDKSTKKLD----IDMLGNMMEASVLSPNRDLYGS 366 + + + +R EAI + +P+ LD IDMLGN+ME+S++SPNR YG Sbjct: 304 KIDVRKLFTWRDQFLEAIQKMAIKMPNGRELPLDEVTGIDMLGNLMESSIISPNRGYYGD 363 Query: 367 IHNNMHSFSAYMHDPEHRYLESFGVIADEATTMRDPFFYRVHAWVDDIFQSFKEAPHNVR 426 +HN H F+AY HDP+HR+LE FGV+ D AT MRDPFFYR H +VDD+F +KE + Sbjct: 364 LHNMGHVFAAYTHDPDHRHLEQFGVMGDSATAMRDPFFYRWHRFVDDVFNIYKE---KLT 420 Query: 427 PYSRSQLENPGVQVTSVAVESAGGQQNVLNTFWMQSDVNLSKGLDFSDRGPVYARFTHLN 486 PY+ +L+ PGV+V+SV +E G + N L T W QS V L +GLDF+ RG V ARFTHL Sbjct: 421 PYTNERLDFPGVRVSSVGIE--GARPNTLRTLWQQSTVELGRGLDFTPRGSVLARFTHLQ 478 Query: 487 HRPFRYVIKANNTASAR-RTTVRIFIAPKTDERNLPWALSDQRKMFIEMDRFVVPLSAGE 545 H F+YVI+ NNT TVRIF+APK D+ P + + QR++ IE+D+F L G Sbjct: 479 HDEFQYVIEVNNTTGGNLMGTVRIFMAPKVDDNGQPMSFNKQRRLMIELDKFSQALRPGT 538 Query: 546 NTITRQSTESSLTIPFEQTFRDLSIQGSDPRRSELAAFNYCGCGWPQHMLVPKGTVGGVA 605 NTI R+S +SS+TIP+E+TFR+ S + DP + A F++CGCGWP HML+PKGT G Sbjct: 539 NTIRRRSVDSSVTIPYERTFRNQSERPGDPGTAGAAEFDFCGCGWPHHMLIPKGTAQGYP 598 Query: 606 YQLFVMLSNYELDKIEQPDGRELSCVEASMFCGLKDKKYPDARPMGYPFDRP-SNSATNI 664 LFVM+SN+ D+IEQ SC +A+ +CG++D+KYPD + MGYPFDR +N A + Sbjct: 599 VVLFVMISNWNNDRIEQ--DLVGSCNDAASYCGIRDRKYPDKQAMGYPFDRKMANDAATL 656 Query: 665 EDFSAMSNMGLQDIVIKLSDVT 686 DF NM ++D I+ SD T Sbjct: 657 SDF-LRPNMAVRDCSIQFSDTT 677 >1NOL-A nrPDB Length = 628 Score = 818 bits (2113), Expect = 0.0, Method: Composition-based stats. Identities = 245/639 (38%), Positives = 372/639 (58%), Gaps = 34/639 (5%) Query: 56 EEVSRKIILKNLDKIPEFPKAK---QLPNDADFSLFLPSHQEMANEVIDVLMSVTENQLQ 112 E++S ++ + DK + K +L A FS F P H E A + +V + Sbjct: 14 EQLSSATVIGDGDKHKHSDRLKNVGKLQPGAIFSCFHPDHLEEARHLYEVFWEAGD--FN 71 Query: 113 ELLSTCVYARINLNPQLFNYCYTVAIMHRRDTGKVRVQNYAEIFPAKFLDSQVFTQAREA 172 + + AR +N LF + VA++HR D + V EIFP KF+ S +A + Sbjct: 72 DFIEIAKEARTFVNEGLFAFAAEVAVLHRDDCKGLYVPPVQEIFPDKFIPSAAINEAFKK 131 Query: 173 AAVIPKTIPRTPIIIPRDYTATDLEEEHRLAYWREDLGINLHHWHWHLVYPFSASDEKIV 232 A V P+ +PI++ T L+ E+RLAY+RED+GIN HHWHWHLVYP + + + Sbjct: 132 AHVRPE-FDESPILVDVQDTGNILDPEYRLAYYREDVGINAHHWHWHLVYPSTWNPKYFG 190 Query: 233 AK-DRRGELFFYMHQQIIARYNCERLCNSLKRVKKFSDWREPIPEAYYPKLDSLTSARGW 291 K DR+GELF+YMHQQ+ ARY+CERL N + R+ F+++ EP+ Y P L + S + + Sbjct: 191 KKKDRKGELFYYMHQQMCARYDCERLSNGMHRMLPFNNFDEPLA-GYAPHLTHVASGKYY 249 Query: 292 PPRQAGMRWQDLKRPVDGLNVTIDDMERYRRNIEEAIATGNVILPDKSTKKLD----IDM 347 PR G++ +DL ++ I +M R R I ++I G VI D S K LD D+ Sbjct: 250 SPRPDGLKLRDLG------DIEISEMVRMRERILDSIHLGYVISEDGSHKTLDELHGTDI 303 Query: 348 LGNMMEASVLSPNRDLYGSIHNNMHSFSAYMHDPEHRYLESFGVIADEATTMRDPFFYRV 407 LG ++E+S S N + YG++HN H A +HDP+ R+ E GV++D +T++RDP FY Sbjct: 304 LGALVESSYESVNHEYYGNLHNWGHVTMARIHDPDGRFHEEPGVMSDTSTSLRDPIFYNW 363 Query: 408 HAWVDDIFQSFKEAPHNVRPYSRSQLENPGVQVTSVAVESAGGQQNVLNTFWMQSDVNLS 467 H ++D+IF +K ++PY L P +QV V + + NV++TF + ++ L Sbjct: 364 HRFIDNIFHEYKNT---LKPYDHDVLNFPDIQVQDVTLHAR--VDNVVHTFMREQELELK 418 Query: 468 KGLDFSDRGPVYARFTHLNHRPFRYVIKA-NNTASARRTTVRIFIAPKTDERNLPWALSD 526 G++ + + AR+ HL+H PF Y + NN+AS + TVRIF+APK DE + Sbjct: 419 HGINPGNARSIKARYYHLDHEPFSYAVNVQNNSASDKHATVRIFLAPKYDELGNEIKADE 478 Query: 527 QRKMFIEMDRFVVPLSAGENTITRQSTESSLTIPFEQTFRD-LSIQGSDPRRSELAAFNY 585 R+ IE+D+F L G+NT+ R S +SS+T+ + TF D L G + +SE Y Sbjct: 479 LRRTAIELDKFKTDLHPGKNTVVRHSLDSSVTLSHQPTFEDLLHGVGLNEHKSE-----Y 533 Query: 586 CGCGWPQHMLVPKGTVGGVAYQLFVMLSNYELDKIEQPDGRELSCVEASMFCGLKDKKYP 645 C CGWP H+LVPKG + G+ Y LFVML++++ DK++ + ++CV+A +CG +D KYP Sbjct: 534 CSCGWPSHLLVPKGNIKGMEYHLFVMLTDWDKDKVDGSES--VACVDAVSYCGARDHKYP 591 Query: 646 DARPMGYPFDRPSNSATNIEDFSAMSNMGLQDIVIKLSD 684 D +PMG+PFDRP ++ +I DF +NM ++DI IK + Sbjct: 592 DKKPMGFPFDRPIHTE-HISDF-LTNNMFIKDIKIKFHE 628 >3IXV-A nrPDB Length = 626 Score = 814 bits (2102), Expect = 0.0, Method: Composition-based stats. Identities = 236/611 (38%), Positives = 356/611 (58%), Gaps = 30/611 (4%) Query: 79 LPNDADFSLFLPSHQEMANEVIDVLMSVTENQLQELLSTCVYARINLNPQLFNYCYTVAI 138 LP FS F H A E+ L + + + C AR +N +F Y +VA+ Sbjct: 39 LPRGTLFSCFHARHLAEATELYVALYGAKD--FNDFIHLCEQARQIVNEGMFVYAVSVAV 96 Query: 139 MHRRDTGKVRVQNYAEIFPAKFLDSQVFTQAREAAAVIPKTIPRTPIIIPRDYTATDLEE 198 +HR D + V E+FP +F+ ++ +A + A+ P + I++ + T L+ Sbjct: 97 LHREDCKGITVPPIQEVFPDRFVPAETINRANKEASNHPD---QQSIVVEAEETGNILDP 153 Query: 199 EHRLAYWREDLGINLHHWHWHLVYPFSASDEKIVA-KDRRGELFFYMHQQIIARYNCERL 257 E++L+Y+RED+GIN HHWHWH+VYP + + + KDR+GELFFYMHQQ+ ARY+ ERL Sbjct: 154 EYKLSYFREDIGINAHHWHWHIVYPATWNPTVMGKEKDRKGELFFYMHQQMCARYDSERL 213 Query: 258 CNSLKRVKKFSDWREPIPEAYYPKLDSLTSARGWPPRQAGMRWQDLKRPVDGLNVTIDDM 317 N L+R+ F ++ EP+ E Y P L SL S + R G DL +V + DM Sbjct: 214 SNGLQRMIPFHNFDEPL-EGYAPHLTSLVSGLQYASRPEGYSIHDLS------DVDVQDM 266 Query: 318 ERYRRNIEEAIATGNVILPDKSTKKLDI----DMLGNMMEASVLSPNRDLYGSIHNNMHS 373 R+R I +AI ++ D + LDI D+LG+++E+S S N + YGS+HN H Sbjct: 267 VRWRERILDAINMHYIVDKDNNKIPLDIEHGTDILGDIIESSDESKNVEYYGSLHNWGHV 326 Query: 374 FSAYMHDPEHRYLESFGVIADEATTMRDPFFYRVHAWVDDIFQSFKEAPHNVRPYSRSQL 433 A + DP+HR+ E+ GV++D +T++RDP FYR H ++D+IFQ K++ H PY++ +L Sbjct: 327 MMANITDPDHRFQENPGVMSDTSTSLRDPIFYRWHRFIDNIFQEHKKSFH---PYTKEEL 383 Query: 434 ENPGVQVTSVAVESAGGQQNVLNTFWMQSDVNLSKGLDFSDRGPVYARFTHLNHRPFRYV 493 PGV+V V++ S NV+ T +S + LS G++F V ++ HL+H PF Y Sbjct: 384 SFPGVEVVGVSINSKTA--NVITTLIKESLLELSHGINFGTDQSVKVKYHHLDHEPFTYN 441 Query: 494 IKA-NNTASARRTTVRIFIAPKTDERNLPWALSDQRKMFIEMDRFVVPLSAGENTITRQS 552 I NN+ + + +TVRIF+APK DE N +QR++FIE+D+F L+ G+NTI R Sbjct: 442 IVVENNSGAEKHSTVRIFLAPKYDELNNKLEPDEQRRLFIELDKFFYTLTPGKNTIVRNH 501 Query: 553 TESSLTIPFEQTFRDLSIQGSDPRRSELAAFNYCGCGWPQHMLVPKGTVGGVAYQLFVML 612 +SS+TI +TF L G+ SE + YC CGWP+HML+P+G+ G+ ++LFVML Sbjct: 502 QDSSVTISKVRTFDQL---GAGEGVSEDST-EYCSCGWPEHMLIPRGSHKGMEFELFVML 557 Query: 613 SNYELDKIEQPDGRELSCVEASMFCGLKDKKYPDARPMGYPFDRPSNSATNIEDFSAMSN 672 ++++ D + + C +A +CG +D +YPD + MG+PFDR + T E N Sbjct: 558 TDHDEDTVAGLSENAV-CSDAVSYCGARDDRYPDKKAMGFPFDRKIEARTAAEF--LTPN 614 Query: 673 MGLQDIVIKLS 683 MGL DI IK Sbjct: 615 MGLTDIKIKFH 625 >1HC1-A nrPDB Length = 657 Score = 688 bits (1776), Expect = 0.0, Method: Composition-based stats. Identities = 183/619 (29%), Positives = 291/619 (47%), Gaps = 39/619 (6%) Query: 70 IPEFPKAKQLPNDADFSLFLPSHQEMANEVIDVLMSVTENQLQELLSTCVYARINLNPQL 129 + E + L +SLF ++ A + VL E S Y R +N Sbjct: 57 MKELNDHRLLEQRHWYSLFNTRQRKEALMLFAVLNQCKEWYC--FRSNAAYFRERMNEGE 114 Query: 130 FNYCYTVAIMHRRDTGKVRVQNYAEIFPAKFLDSQVFTQAREAAAVIPKTIPRTPIIIPR 189 F Y V+++H + + + +I P F +S+V +A A + + P Sbjct: 115 FVYALYVSVIHSKLGDGIVLPPLYQITPHMFTNSEVIDKAYSAK------MTQKPGTFNV 168 Query: 190 DYTATDLEEEHRLAYWREDLGINLHHWHWHLVYPFSASDEKIVAKDRRGELFFYMHQQII 249 +T T E R+AY+ ED+G+N+HH WH+ +PF D DR+GELFF++H Q+ Sbjct: 169 SFTGTKKNREQRVAYFGEDIGMNIHHVTWHMDFPFWWEDSYGYHLDRKGELFFWVHHQLT 228 Query: 250 ARYNCERLCNSLKRVKKFSDWREPIPEAYYPKLDSLTSARGWPPRQAGMRWQDLKRPVDG 309 AR++ ERL N L V + W I E + P L S +P R + ++D VDG Sbjct: 229 ARFDFERLSNWLDPVDELH-WDRIIREGFAP-LTSYKYGGEFPVRPDNIHFED----VDG 282 Query: 310 LNVTIDDMERYRRNIEEAIATGNVILPDKSTKKL----DIDMLGNMMEASVLSPNRDLYG 365 + + D+E I EAI G + D T + I++LG+++E+S S N YG Sbjct: 283 V-AHVHDLEITESRIHEAIDHGYITDSDGHTIDIRQPKGIELLGDIIESSKYSSNVQYYG 341 Query: 366 SIHNNMHSFSAYMHDPEHRYLESFGVIADEATTMRDPFFYRVHAWVDDIFQSFKEAPHNV 425 S+HN H DP ++ GV+ T RDP F+R+H ++D+IF+ ++ Sbjct: 342 SLHNTAHVMLGRQGDPHGKFNLPPGVMEHFETATRDPSFFRLHKYMDNIFKKHTDS---F 398 Query: 426 RPYSRSQLENPGVQVTSVAVESAGGQQNVLNTFWMQSDVNLSKGLDFSDR---GPVYARF 482 PY+ LE G+ V VA++ L TF+ + +L +D + + AR Sbjct: 399 PPYTHDNLEFSGMVVNGVAIDGE------LITFFDEFQYSLINAVDSGENIEDVEINARV 452 Query: 483 THLNHRPFRYVIK-ANNTASARRTTVRIFIAPKTDERNLPWALSDQRKMFIEMDRFVVPL 541 LNH F Y I +NN R T RIF+ P D + L + R IE+D+F + Sbjct: 453 HRLNHNEFTYKITMSNNNDGERLATFRIFLCPIEDNNGITLTLDEARWFCIELDKFFQKV 512 Query: 542 SAGENTITRQSTESSLTIPFEQTFRDLSIQGSDPRRS----ELAAFNYCGCGWPQHMLVP 597 +G TI R S +SS+T+P +F+ L Q + +L+A+ CG P ML+P Sbjct: 513 PSGPETIERSSKDSSVTVPDMPSFQSLKEQADNAVNGGHDLDLSAYER-SCGIPDRMLLP 571 Query: 598 KGTVGGVAYQLFVMLSNYELDKIEQPDGRELSCVEASMFCGLKDKKYPDARPMGYPFDRP 657 K G+ + L+V +++ + D G + A CG+ + YPD RP+GYP +R Sbjct: 572 KSKPEGMEFNLYVAVTDGDKDTEGHNGGHDYGGTHAQ--CGVHGEAYPDNRPLGYPLERR 629 Query: 658 SNSATNIEDFSAMSNMGLQ 676 I+ S + ++ ++ Sbjct: 630 IPDERVIDGVSNIKHVVVK 648 >3GWJ-A nrPDB Length = 674 Score = 576 bits (1485), Expect = e-165, Method: Composition-based stats. Identities = 165/653 (25%), Positives = 280/653 (42%), Gaps = 87/653 (13%) Query: 79 LPNDADFSLFLPSHQEMANEVIDVL-MSVTENQLQELLSTCVYARINLNPQLFNYCYTVA 137 LP +FS+F H ++ +E I + + + +AR++LN F Y Y +A Sbjct: 69 LPKYNEFSVF---HDKLRDEAIALFHLFYYAKDFDTFYKSAAFARVHLNQGQFLYAYYIA 125 Query: 138 IMHRRDTGKVRVQNYAEIFPAKFLD----SQVFTQAREAAAVIPKTIPRTPIIIPRDYTA 193 I+ R+DT + + EI+P F++ ++F + + P+ I+ ++ Sbjct: 126 IIQRKDTYGIVLPAPYEIYPELFVNIDTTYKMFRTKMQNGLINPEAAVEYGIVKEDNHYV 185 Query: 194 ---------TDLEEEHRLAYWREDLGINLHHWHWHLVYPFSASDEKIVA-KDRRGELFFY 243 T EE RLAY+ ED+G+N +++ +H+ PF + EK K+RRGE++ Y Sbjct: 186 YYSNYSNAITYYNEEQRLAYFTEDIGLNAYYFFFHIHLPFWWTAEKYGNLKERRGEMYHY 245 Query: 244 MHQQIIARYNCERLCNSLKRVKKFSDWREPIPEAYYPKLDSLTSARGWPPRQAGMRWQDL 303 + Q++ RY ERL N L + +FS W P+ +YP L S + P + ++ Sbjct: 246 FYDQLLTRYYFERLTNGLGTIPEFS-WYSPVKTGHYPLLTSYYTPFSQRPNFYNVHSEEN 304 Query: 304 KRPVDGLNVTIDDMERYRRNIEEAIATGNVILPDKSTKKLDIDMLGNMMEASVLSPNRDL 363 + L+ Y +A+ G V T L+ D N + N DL Sbjct: 305 YEKIRFLDA-------YENYFVQALQKG-VFEGFGQTIYLN-DSKANSFVGNYWQDNADL 355 Query: 364 YGS--IHNNMHSFSAYMHD-------PEHRYLESFGVIADEATTMRDPFFYRVHAWVDDI 414 YG + S+ P +Y + T++RDP FY+++ + Sbjct: 356 YGEEVTKDYQRSYEIVARQVLGAAPKPFDKYTFMPSALDFYQTSLRDPTFYQLYNRIIGY 415 Query: 415 FQSFKEAPHNVRPYSRSQLENPGVQVTSVAVESAGGQQNVLNTFWMQSDVNLSKGLDFSD 474 F FK+ + P+S+ +L GV+V +V V+ L TF+ D + + + F Sbjct: 416 FNQFKQY---LEPHSQEKLHFVGVKVNNVVVDK-------LVTFFEYYDFDATNTV-FLT 464 Query: 475 RGPVYARFTH--------LNHRPFRYVIKANNTASARRTTVRIFIAPKTDERNLPWALSD 526 + ++ H LNH+PF I A V+IF+ PK +E P L + Sbjct: 465 EEELKTKYPHNLKVRQPRLNHQPFNINIDIKADV-ATDAVVKIFMGPKYNENGFPITLEN 523 Query: 527 QRKMFIEMDRFVVPLSAGENTITRQSTESSL----TIPFEQTFRDLSIQGSDPRRSELAA 582 F EMD F ++ G+NTI R S E + ++P + ++ L +G P Sbjct: 524 DWMKFFEMDWFTHKITPGQNTIVRNSNEFVIFKEDSLPSTELYKLL-EKGKVPFDMS-ED 581 Query: 583 FNYCGCGWPQHMLVPKGTVGGVAYQLFVMLSNYELDKIEQPDGRELSCVEASMFCGLKDK 642 F Y P+ +++P+GT GG +Q V + +E + L+ E M Sbjct: 582 FGYL----PKRLMLPRGTKGGFPFQFVVFVYPFE------STTKNLTPYEKFMI------ 625 Query: 643 KYPDARPMGYPFDRPSNSATNIEDFSAMSNMGLQDIVIKLSDVTEPNPRNPPA 695 D +P+GYPFDRP +++ N+ +D+ + N PA Sbjct: 626 ---DNKPLGYPFDRPVDTSC-----FKQPNIFFRDVSVYHEGEYHAYEYNVPA 670 >6ELS-A nrPDB Length = 506 Score = 42.4 bits (98), Expect = 7e-04, Method: Composition-based stats. Identities = 38/192 (19%), Positives = 67/192 (34%), Gaps = 31/192 (16%) Query: 240 LFFYMHQQIIARYNCER----LCNSLKRVKKFSDWREP----IPEAYY----PKLDSLTS 287 LFF H+ + Y E+ L N F +W P +P Y P D L S Sbjct: 113 LFFPFHRYYL--YFFEKILGKLINDPTFALPFWNWDSPAGMPLPAIYADPKSPLYDKLRS 170 Query: 288 ARGWPPRQAGMRWQDLKRPVDGLNVTIDDMERYRRNIEEAIATGNVILPDKSTKKLDIDM 347 A PP + + + V +++ R + + + + D Sbjct: 171 ANHQPPTLVDLDYNGTEDNVSKETTINANLKIMYRQMVSNSKNAKLFFGNPYRAGDEPDP 230 Query: 348 LGNMMEASVLSPNRDLYGSIHNNMHSFSAYMHDPEHRYLESFGVIADEATTMRDPFFYRV 407 G +E G+ H +H ++ P +F + + + RDP F+ Sbjct: 231 GGGSIE-----------GTPHAPVHLWTGDNTQP------NFEDMGNFYSAGRDPIFFAH 273 Query: 408 HAWVDDIFQSFK 419 H+ VD ++ +K Sbjct: 274 HSNVDRMWSIWK 285 >6HQJ-A nrPDB Length = 506 Score = 38.6 bits (88), Expect = 0.010, Method: Composition-based stats. Identities = 39/199 (19%), Positives = 65/199 (32%), Gaps = 28/199 (14%) Query: 240 LFFYMHQQIIARYNCERLCNSLKRVK----KFSDWREPIPEAYYPKLDSLTSARGWPPRQ 295 LFF H+ + Y ER+ SL F +W P + P D +A R Sbjct: 115 LFFPFHRWYL--YFYERILGSLIDDPTFGLPFWNWDHPKGMRFPPMFDVPGTALYDERRG 172 Query: 296 AGMR---WQDLKRPVDGLNVTIDDMERYRRNIEEAIATGNVILPDKSTKKL----DIDML 348 + + DL D + T + + L S L L Sbjct: 173 DQIHNGNFIDLGSFGDQVETTQLQLMT------NNLTLMYRQLVTNSPCPLMFFGGPYTL 226 Query: 349 GNMMEASVLSPNRDLYGSIHNNMHSFSAYMHD---PEHRYLESFGVIADEATTMRDPFFY 405 G+ +EA+ N H+ +H + P+ + + + + DP FY Sbjct: 227 GSTVEAAGTVENIP-----HSPVHIWVGTRRGSVLPDGKISNGEDMGNFYSAGL-DPLFY 280 Query: 406 RVHAWVDDIFQSFKEAPHN 424 H+ VD ++ +K Sbjct: 281 CHHSNVDRMWNEWKATGGK 299 >1PE9-A nrPDB Length = 361 Score = 35.1 bits (79), Expect = 0.12, Method: Composition-based stats. Identities = 20/82 (24%), Positives = 32/82 (39%), Gaps = 5/82 (6%) Query: 315 DDMERYRRNIEEAIATGNVI---LPDKS--TKKLDIDMLGNMMEASVLSPNRDLYGSIHN 369 D ++ + +I + S KL + + N+ R YGSIH+ Sbjct: 193 SDYVTISNSLIDQHDKTMLIGHSDSNGSQDKGKLHVTLFNNVFNRVTERAPRVRYGSIHS 252 Query: 370 NMHSFSAYMHDPEHRYLESFGV 391 + F DP +RY SFG+ Sbjct: 253 FNNVFKGDAKDPVYRYQYSFGI 274 >4Z13-A nrPDB Length = 520 Score = 34.7 bits (78), Expect = 0.12, Method: Composition-based stats. Identities = 41/195 (21%), Positives = 68/195 (34%), Gaps = 30/195 (15%) Query: 240 LFFYMHQQIIARYNCERLCNSLKRVKKFS----DWREP---------IPEAYYPKLDSLT 286 LFF H+ + Y ER+ SL F+ W EP + +A P D Sbjct: 123 LFFPFHRWYL--YFYERILGSLIDEPNFALPYWKWDEPKGMPISNIFLGDASNPLYDQYR 180 Query: 287 SARGWPPRQAGMRWQDLKRPV-DGLNVTIDDMERYRRNIEEAIATGNVILPDKSTKKLDI 345 A R + + + + D V + YR + + + K + Sbjct: 181 DANHIEDRIVDLDYDGKDKDIPDQQQVACNLSTVYRDLVRNGVDPTSFFGG----KYVAG 236 Query: 346 DMLGNMMEASVLSPNRDLYGSIHNNMHSFSAYMHDPEHRYLESFGVIADEATTMRDPFFY 405 D + SV S + ++H + DP E + + + DP FY Sbjct: 237 DSPVANGDPSVGSVEAGSHTAVHRW-------VGDPTQPNNED---MGNFYSAGYDPVFY 286 Query: 406 RVHAWVDDIFQSFKE 420 HA VD +++ +KE Sbjct: 287 IHHANVDRMWKLWKE 301 >2P3X-A nrPDB Length = 339 Score = 34.7 bits (78), Expect = 0.16, Method: Composition-based stats. Identities = 34/187 (18%), Positives = 65/187 (34%), Gaps = 31/187 (16%) Query: 241 FFYMHQQIIARYNCERLCNSLKRVKKFSDWREP----IPEAYYPKLDSLT----SARGWP 292 + Y +++I+A+ L + + W P +P Y SL +A+ P Sbjct: 120 YLYFNERILAK-----LIDDPTFALPYWAWDNPDGMYMPTIYASSPSSLYDEKRNAKHLP 174 Query: 293 PRQAGMRWQDLKRPVDGLNVTIDDMERYRRNIEEAIATGNVILPDKSTKKLDIDMLGNMM 352 P + + + + + D++ + I T + L ID + Sbjct: 175 PTVIDLDYDGTEPTIPDDELKTDNLAIMYKQIVSGATTPKLFLGYPYRAGDAIDPGAGTL 234 Query: 353 EASVLSPNRDLYGSIHNNMHSFSAYMHDPEHRYLESFGVIADEATTMRDPFFYRVHAWVD 412 E + HN +H ++ P + + T RDP F+ HA VD Sbjct: 235 EHAP-----------HNIVHKWTGLADKPSED-------MGNFYTAGRDPIFFGHHANVD 276 Query: 413 DIFQSFK 419 ++ +K Sbjct: 277 RMWNIWK 283 >4Z0Z-A nrPDB Length = 350 Score = 34.3 bits (77), Expect = 0.20, Method: Composition-based stats. Identities = 40/195 (20%), Positives = 67/195 (34%), Gaps = 30/195 (15%) Query: 240 LFFYMHQQIIARYNCERLCNSL----KRVKKFSDWREP---------IPEAYYPKLDSLT 286 LFF H+ + Y ER+ SL + W EP + +A P D Sbjct: 120 LFFPFHRWYL--YFYERILGSLIDEPNFALPYWKWDEPKGMPISNIFLGDASNPLYDQYR 177 Query: 287 SARGWPPRQAGMRWQDLKRPV-DGLNVTIDDMERYRRNIEEAIATGNVILPDKSTKKLDI 345 A R + + + + D V + YR + + + K + Sbjct: 178 DANHIEDRIVDLDYDGKDKDIPDQQQVACNLSTVYRDLVRNGVDPTSFFGG----KYVAG 233 Query: 346 DMLGNMMEASVLSPNRDLYGSIHNNMHSFSAYMHDPEHRYLESFGVIADEATTMRDPFFY 405 D + SV S + ++H + DP E + + + DP FY Sbjct: 234 DSPVANGDPSVGSVEAGSHTAVHRW-------VGDPTQPNNED---MGNFYSAGYDPVFY 283 Query: 406 RVHAWVDDIFQSFKE 420 HA VD +++ +KE Sbjct: 284 IHHANVDRMWKLWKE 298 >5CE9-A nrPDB Length = 339 Score = 33.2 bits (74), Expect = 0.37, Method: Composition-based stats. Identities = 30/192 (15%), Positives = 63/192 (32%), Gaps = 31/192 (16%) Query: 240 LFFYMHQQIIARYNCERLCNSL----KRVKKFSDWREP----IPEAYYPKLDSLTSAR-- 289 LFF H+ + Y E++ L F +W P +P Y ++ Sbjct: 112 LFFPFHRYYV--YFFEKILGKLIGDPTFALPFWNWDSPPGMQLPSLYAVSNSAIYDPLRN 169 Query: 290 --GWPPRQAGMRWQDLKRPVDGLNVTIDDMERYRRNIEEAIATGNVILPDKSTKKLDIDM 347 PP + + + + +++ R + + + D Sbjct: 170 ANHQPPTIIDLDYGETSESTTTTDQVPSNLKIMYRQMVSGAKNPTLFFGSPYRAGDEPDP 229 Query: 348 LGNMMEASVLSPNRDLYGSIHNNMHSFSAYMHDPEHRYLESFGVIADEATTMRDPFFYRV 407 +E++ HNN+H ++ P + + + + RDP F+ Sbjct: 230 GAGTIESTP-----------HNNIHLWTGDDTQP------NIENMGNFYSAGRDPIFFAH 272 Query: 408 HAWVDDIFQSFK 419 H+ VD ++ +K Sbjct: 273 HSNVDRMWTIWK 284 >3BSH-A nrPDB Length = 414 Score = 32.4 bits (72), Expect = 0.63, Method: Composition-based stats. Identities = 14/81 (17%), Positives = 25/81 (30%), Gaps = 5/81 (6%) Query: 260 SLKRVKKFSDWREPIPEAYYPKLDSLTSARGWPPRQAGMRWQDLKRPVDG-----LNVTI 314 LK F WR Y P++ + P W ++ DG + Sbjct: 167 WLKSDLGFDAWRLDFARGYSPEMAKVYIDGTSPSLAVAEVWDNMATGGDGKPNYDQDAHR 226 Query: 315 DDMERYRRNIEEAIATGNVIL 335 ++ + + A + G V Sbjct: 227 QNLVNWVDKVGGAASAGMVFD 247 >5TX1-M nrPDB Length = 388 Score = 32.0 bits (71), Expect = 0.99, Method: Composition-based stats. Identities = 13/71 (18%), Positives = 27/71 (38%), Gaps = 2/71 (2%) Query: 321 RRNIEEAIAT--GNVILPDKSTKKLDIDMLGNMMEASVLSPNRDLYGSIHNNMHSFSAYM 378 I + G ++ + +T +DM ME S+ + NR + + +H +A Sbjct: 314 EERILRYVQQSVGLFLMQEGATPSAALDMTARNMEPSMYAANRPFINKLMDYLHRAAAMN 373 Query: 379 HDPEHRYLESF 389 D + + Sbjct: 374 TDYFTNAILNP 384 >6M9Z-A nrPDB Length = 230 Score = 31.6 bits (70), Expect = 1.1, Method: Composition-based stats. Identities = 36/210 (17%), Positives = 68/210 (32%), Gaps = 18/210 (8%) Query: 337 DKSTKKLDIDMLGNMMEASVLSPNRDLYGSIHNNMHSFSAYMHDPEHRYLESFGVIADEA 396 + + + GN E S + G + + + ++ ++YL ++ Sbjct: 16 NGVKFDMVGEGTGNPNEGSEELKLKSTNGPLKFSPYILVPHLGYGFNQYLPFPDGMSPFQ 75 Query: 397 TTMRDPFFYRVHA---WVDDIFQSFKEAPHNVRPYSRSQLENPG-VQVTSVAVESAGGQQ 452 M+D Y+VH + D F N+R Y+ G QV G Sbjct: 76 AAMQDESGYQVHRTLQYEDGAF-----VTANLR-YTYEGSHIKGEFQVIGTGFPPDGPVM 129 Query: 453 NVLNTFWMQSDVNLSKGLDFSDRGPVYARFTHLNHRPFRYVIKANNTASARRTT-----V 507 T S V D + +T + + ++ + NNT + Sbjct: 130 TNKLTALDWSVVKFVYPNDKTILSTFDKTYTTTDGKRYQCTFRENNTFAKPMAADILQKQ 189 Query: 508 RIFIAPKTD---ERNLPWALSDQRKMFIEM 534 +FI KT+ N +++ F +M Sbjct: 190 PMFIFHKTELQHSNNAELTFKEKQTAFSDM 219 >5MWC-D nrPDB Length = 311 Score = 30.5 bits (67), Expect = 2.9, Method: Composition-based stats. Identities = 29/140 (20%), Positives = 45/140 (32%), Gaps = 16/140 (11%) Query: 337 DKSTKKLDIDMLGNMMEASVLSPNRDL--------YGSIHNNMHSFSAYMHDPEHRYLES 388 S +D DM+G +PN G + + ++ H+YL Sbjct: 22 FGSINGVDFDMVGQ----GSGNPNVGYEELNLKSTKGDLQFSPWILVPHIGYGFHQYLPY 77 Query: 389 FGVIADEATTMRDPFFYRVHAWVDDIFQSFKEAPHNVRPYSRSQLENPG-VQVTSVAVES 447 ++ M D Y+VH V F+ N R Y+ G QV + Sbjct: 78 PDGMSPFQAAMVDGSGYQVHRTVQ--FEDGASLTVNYR-YTYEGSHIKGEAQVKGTGFPA 134 Query: 448 AGGQQNVLNTFWMQSDVNLS 467 G T + S+ LS Sbjct: 135 DGPVMANSLTAMVPSEEELS 154 >2WC7-A nrPDB Length = 488 Score = 30.1 bits (66), Expect = 3.8, Method: Composition-based stats. Identities = 33/216 (15%), Positives = 64/216 (29%), Gaps = 32/216 (14%) Query: 152 YAEIFPAKFLDSQVFTQA--REAAAVIPKTIPRTPIIIPRDYTATDLEEEHRLAYWREDL 209 + +IFP +F S+ + +EA ++P D + ++ ++L Sbjct: 14 FYQIFPDRFARSKQPRKRLLQEARWEDWDSMPTLQGYKGGDLWGIMEDLDY-----IQNL 68 Query: 210 GINL------------HHWHWHLVYPFSASDEKIVAKDRRGELFFYMHQQIIARYNCERL 257 GIN H +H H Y D + + EL HQ+ N + + Sbjct: 69 GINAIYFTPIFQSASNHRYHTHDYYQV---DPMLGGNEAFKELLDAAHQR-----NIKVV 120 Query: 258 CNSL--KRVKKFSDWREPIPEAYYPKLDSLTSARGWPPRQAGMRWQDLKRPVDGLNVTI- 314 + + + F + + + + + GWP + G Sbjct: 121 LDGVFNHSSRGFFFFHDVLENGPHSPWVNWFKIEGWPLSPYNGEFPANYVGWAGNRALPE 180 Query: 315 --DDMERYRRNIEEAIATGNVILPDKSTKKLDIDML 348 D R I E D + ++ Sbjct: 181 FNHDNPEVREYIMEIAEYWLKFGIDGWRLDVPFEIK 216 >6CGV-M nrPDB Length = 585 Score = 28.9 bits (63), Expect = 7.2, Method: Composition-based stats. Identities = 14/93 (15%), Positives = 39/93 (41%), Gaps = 2/93 (2%) Query: 297 GMRWQDLKRPVDGLNVTIDDMERYRRNIEEAIATGNVILPDKSTKKLDIDMLGNMMEASV 356 + ++ + L+ + ER R ++++++ ++ D T + +DM ME + Sbjct: 298 NYLLTNRRQKIPSLHSLNSEEERILRYVQQSVSLN--LMRDGVTPSVALDMTARNMEPGM 355 Query: 357 LSPNRDLYGSIHNNMHSFSAYMHDPEHRYLESF 389 + NR + + +H +A + + + Sbjct: 356 YASNRPFINRLMDYLHRAAAVNPEYFTNAILNP 388 >4HU8-A nrPDB Length = 456 Score = 28.9 bits (63), Expect = 7.4, Method: Composition-based stats. Identities = 33/207 (15%), Positives = 62/207 (29%), Gaps = 41/207 (19%) Query: 149 VQNYAEIFPAKFLDSQVFTQAREAAAV--IPKTIPRTPIIIPRDY------TATDLEEEH 200 + + F FL +F + ++ I+ P ++ T E Sbjct: 96 LPPLKDHFKDYFLIGNIFNNRDVSGSMMDNDWLAHHYAILTPENHMKPSNLTNNRNETTG 155 Query: 201 RLAY------------WREDLGINLHHWHWHLVYPFSASDEKIVAKDR------------ 236 + Y E L I+ H WH P + AKD Sbjct: 156 EITYTFSTADRMVNAAIAEGLKIHGHTLLWHQQIPPWQRSMESAAKDAALSVMKKYITEV 215 Query: 237 ----RGELFFYMHQQIIARYNCERLCNSLKRVKKFSDWREPIPEAYYPKLDSLTSARGWP 292 +G+++ + + + R N ++ + W + I + ++ +AR Sbjct: 216 MTHYKGKIYSW--DVLNEIFPDGRGDNWTTAMRPENPWFKSIGSDFV--YEAYLAARQAD 271 Query: 293 PRQAGMRWQDLKRPVDGLNVTIDDMER 319 P A + + D G I M R Sbjct: 272 PN-AILYYNDYNMDQAGKAALIAAMVR 297 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.310 0.129 0.348 Lambda K H 0.267 0.0392 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 25,830,894 Number of Sequences: 36641 Number of extensions: 1024437 Number of successful extensions: 2689 Number of sequences better than 10.0: 24 Number of HSP's better than 10.0 without gapping: 18 Number of HSP's successfully gapped in prelim test: 18 Number of HSP's that attempted gapping in prelim test: 2570 Number of HSP's gapped (non-prelim): 38 length of query: 695 length of database: 10,336,785 effective HSP length: 104 effective length of query: 591 effective length of database: 6,526,121 effective search space: 3856937511 effective search space used: 3856937511 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 62 (28.6 bits)