BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q24940 (326 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 2O6X-A nrPDB 632 0.0 7PCK-A nrPDB 271 2e-73 2C0Y-A nrPDB 271 4e-73 3QT4-A nrPDB 265 2e-71 1CJL-A nrPDB 264 3e-71 3QJ3-A nrPDB 246 1e-65 3HWN-A nrPDB 229 1e-60 6CZS-A nrPDB 221 3e-58 3KFQ-A nrPDB 220 5e-58 3OF9-A nrPDB 218 2e-57 4BS5-A nrPDB 218 4e-57 4P6E-A nrPDB 215 2e-56 5JA7-A nrPDB 214 5e-56 6BKI-A nrPDB 208 2e-54 2VHS-A nrPDB 206 8e-54 1NB3-A nrPDB 194 5e-50 3P5W-A nrPDB 186 8e-48 2PNS-A nrPDB 183 7e-47 1CQD-A nrPDB 182 1e-46 5EF4-A nrPDB 179 1e-45 1PCI-A nrPDB 179 2e-45 1S4V-A nrPDB 179 2e-45 3F75-A nrPDB 176 9e-45 3BCN-A nrPDB 176 1e-44 4YYR-A nrPDB 176 2e-44 2FO5-A nrPDB 175 3e-44 4QRX-A nrPDB 174 7e-44 4YYW-A nrPDB 172 1e-43 1O0E-A nrPDB 172 2e-43 2ACT-A nrPDB 171 3e-43 1ICF-A nrPDB 171 4e-43 1AEC-A nrPDB 171 5e-43 1IWD-A nrPDB 168 3e-42 6MIS-A nrPDB 162 2e-40 2B1M-A nrPDB 158 4e-39 5A24-A nrPDB 158 4e-39 1YAL-A nrPDB 158 4e-39 3U8E-A nrPDB 157 7e-39 4YYQ-A nrPDB 155 2e-38 4PI3-A nrPDB 154 4e-38 6EXO-A nrPDB 153 1e-37 2BDZ-A nrPDB 152 2e-37 1PPO-A nrPDB 151 4e-37 1M6D-A nrPDB 150 1e-36 3BPF-A nrPDB 144 4e-35 2CIO-A nrPDB 143 1e-34 1GEC-E nrPDB 139 2e-33 3BPM-A nrPDB 133 9e-32 3PDF-A nrPDB 130 6e-31 1JQP-A nrPDB 129 1e-30 3IOQ-A nrPDB 129 2e-30 5I4H-A nrPDB 127 6e-30 5JT8-A nrPDB 126 1e-29 1XKG-A nrPDB 123 1e-28 5VPK-A nrPDB 121 4e-28 5VCN-A nrPDB 110 8e-25 3PBH-A nrPDB 104 4e-23 1CPJ-A nrPDB 102 2e-22 3CBK-A nrPDB 100 7e-22 1MIR-A nrPDB 100 2e-21 5I4H-B nrPDB 89 2e-18 4HWY-A nrPDB 89 3e-18 4I05-A nrPDB 88 7e-18 1DEU-A nrPDB 87 1e-17 1EF7-A nrPDB 87 1e-17 5OGQ-A nrPDB 86 2e-17 2DCB-A nrPDB 86 3e-17 4I04-A nrPDB 85 5e-17 4OEL-A nrPDB 78 5e-15 1CSB-B nrPDB 77 1e-14 4CDF-B nrPDB 76 2e-14 1SP4-B nrPDB 70 2e-12 4OEM-B nrPDB 66 2e-11 3CH2-X nrPDB 59 2e-09 2L95-A nrPDB 55 5e-08 5FPW-A nrPDB 54 7e-08 3OIS-A nrPDB 39 0.003 2POC-A nrPDB 33 0.20 4D59-A nrPDB 32 0.25 4CI7-A nrPDB 32 0.28 5WDK-A nrPDB 30 1.6 4V0R-A nrPDB 30 1.6 1Z5U-A nrPDB 30 1.9 4K7C-A nrPDB 30 2.1 4C11-A nrPDB 28 5.3 4Z04-A nrPDB 28 7.3 >2O6X-A nrPDB Length = 310 Score = 632 bits (1631), Expect = 0.0, Method: Compositional matrix adjust. Identities = 301/310 (97%), Positives = 302/310 (97%) Query: 17 NDDLWHQWKRMYNKEYNGADDQHRRNIWEKNVKHIQEHNLRHDLGLVTYTLGLNQFTDMT 76 NDDLWHQWKRMYNKEYNGADDQHRRNIWEKNVKHIQEHNLRHDLGLVTYTLGLNQFTDMT Sbjct: 1 NDDLWHQWKRMYNKEYNGADDQHRRNIWEKNVKHIQEHNLRHDLGLVTYTLGLNQFTDMT 60 Query: 77 FEEFKAKYLTEMSRASDILSHGVPYEANNRAVPDKIDWRESGYVTEVKDQGNCGSCWAFS 136 FEEFKAKYLTEMSRASDILSHGVPYEANNRAVPDKIDWRESGYVTEVKDQGNCGS WAFS Sbjct: 61 FEEFKAKYLTEMSRASDILSHGVPYEANNRAVPDKIDWRESGYVTEVKDQGNCGSGWAFS 120 Query: 137 TTGTMEGQYMKNERTSISFSEQQLVDCSGPWGNNGCSGGLMENAYQYLKQFGLETESSYP 196 TTGTMEGQYMKNERTSISFSEQQLVDCS PWGNNGC GGLMENAYQYLKQFGLETESSYP Sbjct: 121 TTGTMEGQYMKNERTSISFSEQQLVDCSRPWGNNGCGGGLMENAYQYLKQFGLETESSYP 180 Query: 197 YTAVEGQCRYNKQLGVAKVTGYYTVHSGSEVELKNLVGARRPAAVAVDVESDFMMYRSGI 256 YTAVEGQCRYNKQLGVAKVTG+YTVHSGSEVELKNLVGA PAAVAVDVESDFMMYRSGI Sbjct: 181 YTAVEGQCRYNKQLGVAKVTGFYTVHSGSEVELKNLVGAEGPAAVAVDVESDFMMYRSGI 240 Query: 257 YQSQTCSPLRVNHAVLAVGYGTQGGTDYWIVKNSWGTYWGERGYIRMARNRGNMCGIASL 316 YQSQTCSPLRVNHAVLAVGYGTQGGTDYWIVKNSWG WGERGYIRM RNRGNMCGIASL Sbjct: 241 YQSQTCSPLRVNHAVLAVGYGTQGGTDYWIVKNSWGLSWGERGYIRMVRNRGNMCGIASL 300 Query: 317 ASLPMVARFP 326 ASLPMVARFP Sbjct: 301 ASLPMVARFP 310 >7PCK-A nrPDB Length = 314 Score = 271 bits (693), Expect = 2e-73, Method: Compositional matrix adjust. Identities = 146/311 (46%), Positives = 187/311 (60%), Gaps = 14/311 (4%) Query: 18 DDLWHQWKRMYNKEYNG-ADDQHRRNIWEKNVKHIQEHNLRHDLGLVTYTLGLNQFTDMT 76 D W WK+ + K+YN D+ RR IWEKN+K+I HNL LG+ TY L +N DMT Sbjct: 8 DTHWELWKKTHRKQYNNKVDEISRRLIWEKNLKYISIHNLEASLGVHTYELAMNHLGDMT 67 Query: 77 FEEFKAKYL-----TEMSRASDILSHGVPYEANNRAVPDKIDWRESGYVTEVKDQGNCGS 131 EE K SR++D L +P E RA PD +D+R+ GYVT VK+QG CGS Sbjct: 68 SEEVVQKMTGLKVPLSHSRSNDTLY--IP-EWEGRA-PDSVDYRKKGYVTPVKNQGQCGS 123 Query: 132 CWAFSTTGTMEGQYMKNERTSISFSEQQLVDCSGPWGNNGCSGGLMENAYQYL-KQFGLE 190 CWAFS+ G +EGQ K ++ S Q LVDC N+GC GG M NA+QY+ K G++ Sbjct: 124 CWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSE--NDGCGGGYMTNAFQYVQKNRGID 181 Query: 191 TESSYPYTAVEGQCRYNKQLGVAKVTGYYTVHSGSEVELKNLVGARRPAAVAVDVE-SDF 249 +E +YPY E C YN AK GY + G+E LK V P +VA+D + F Sbjct: 182 SEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKALKRAVARVGPVSVAIDASLTSF 241 Query: 250 MMYRSGIYQSQTCSPLRVNHAVLAVGYGTQGGTDYWIVKNSWGTYWGERGYIRMARNRGN 309 Y G+Y ++C+ +NHAVLAVGYG Q G +WI+KNSWG WG +GYI MARN+ N Sbjct: 242 QFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILMARNKNN 301 Query: 310 MCGIASLASLP 320 CGIA+LAS P Sbjct: 302 ACGIANLASFP 312 >2C0Y-A nrPDB Length = 315 Score = 271 bits (692), Expect = 4e-73, Method: Compositional matrix adjust. Identities = 140/310 (45%), Positives = 189/310 (60%), Gaps = 8/310 (2%) Query: 18 DDLWHQWKRMYNKEYNGADDQH-RRNIWEKNVKHIQEHNLRHDLGLVTYTLGLNQFTDMT 76 D WH WK+ Y K+Y +++ RR IWEKN+K + HNL H +G+ +Y LG+N DMT Sbjct: 9 DHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFVMLHNLEHSMGMHSYDLGMNHLGDMT 68 Query: 77 FEEFKAKYLTEMSRASDILSHGVPYEAN-NRAVPDKIDWRESGYVTEVKDQGNCGSCWAF 135 EE + L R + Y++N NR +PD +DWRE G VTEVK QG+CG+ WAF Sbjct: 69 SEEVMS--LMSSLRVPSQWQRNITYKSNPNRILPDSVDWREKGCVTEVKYQGSCGAAWAF 126 Query: 136 STTGTMEGQYMKNERTSISFSEQQLVDCSG-PWGNNGCSGGLMENAYQYL-KQFGLETES 193 S G +E Q +S S Q LVDCS +GN GC+GG M A+QY+ G+++++ Sbjct: 127 SAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDA 186 Query: 194 SYPYTAVEGQCRYNKQLGVAKVTGYYTVHSGSEVELKNLVGARRPAAVAVDV-ESDFMMY 252 SYPY A++ +C+Y+ + A + Y + G E LK V + P +V VD F +Y Sbjct: 187 SYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKEAVANKGPVSVGVDARHPSFFLY 246 Query: 253 RSGIYQSQTCSPLRVNHAVLAVGYGTQGGTDYWIVKNSWGTYWGERGYIRMARNRGNMCG 312 RSG+Y +C+ VNH VL VGYG G +YW+VKNSWG +GE GYIRMARN+GN CG Sbjct: 247 RSGVYYEPSCTQ-NVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARNKGNHCG 305 Query: 313 IASLASLPMV 322 IAS S P + Sbjct: 306 IASFPSYPEI 315 >3QT4-A nrPDB Length = 329 Score = 265 bits (677), Expect = 2e-71, Method: Compositional matrix adjust. Identities = 134/305 (43%), Positives = 186/305 (60%), Gaps = 5/305 (1%) Query: 21 WHQWKRMYNKEYNGADDQHRRN-IWEKNVKHIQEHNLRHDLGLVTYTLGLNQFTDMTFEE 79 W Q+K + K Y+ ++ RR I++ NV I EHN + + G VTY+ +NQF DM+ EE Sbjct: 27 WSQFKLTHKKSYSSPIEEIRRQLIFKDNVAKIAEHNAKFEKGEVTYSKAMNQFGDMSKEE 86 Query: 80 FKAKYLT--EMSRASDILSHGVPYEANNRAVPDKIDWRESGYVTEVKDQGNCGSCWAFST 137 F A Y+ + + + +PY ++ + + +DWR S V+EVKDQG CGS W+FST Sbjct: 87 FLA-YVNRGKAQKPKHPENLRMPYVSSKKPLAASVDWR-SNAVSEVKDQGQCGSSWSFST 144 Query: 138 TGTMEGQYMKNERTSISFSEQQLVDCSGPWGNNGCSGGLMENAYQYLKQFGLETESSYPY 197 TG +EGQ S SEQ L+DCS +GN GC GG M++A+ Y+ +G+ +ES+YPY Sbjct: 145 TGAVEGQLALQRGRLTSLSEQNLIDCSSSYGNAGCDGGWMDSAFSYIHDYGIMSESAYPY 204 Query: 198 TAVEGQCRYNKQLGVAKVTGYYTVHSGSEVELKNLVGARRPAAVAVDVESDFMMYRSGIY 257 A CR++ V ++GYY + SG E L + VG P AVA+D + Y G++ Sbjct: 205 EAQGDYCRFDSSQSVTTLSGYYDLPSGDENSLADAVGQAGPVAVAIDATDELQFYSGGLF 264 Query: 258 QSQTCSPLRVNHAVLAVGYGTQGGTDYWIVKNSWGTYWGERGYIRMARNRGNMCGIASLA 317 QTC+ +NH VL VGYG+ G DYWI+KNSWG+ WGE GY R RN GN CGIA+ A Sbjct: 265 YDQTCNQSDLNHGVLVVGYGSDNGQDYWILKNSWGSGWGESGYWRQVRNYGNNCGIATAA 324 Query: 318 SLPMV 322 S P + Sbjct: 325 SYPAL 329 >1CJL-A nrPDB Length = 312 Score = 264 bits (675), Expect = 3e-71, Method: Compositional matrix adjust. Identities = 140/311 (45%), Positives = 183/311 (58%), Gaps = 15/311 (4%) Query: 21 WHQWKRMYNKEYNGADDQHRRNIWEKNVKHIQEHNLRHDLGLVTYTLGLNQFTDMTFEEF 80 W +WK M+N+ Y ++ RR +WEKN+K I+ HN + G ++T+ +N F DMT EEF Sbjct: 8 WTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIELHNQEYREGKHSFTMAMNAFGDMTSEEF 67 Query: 81 KA---KYLTEMSRASDILSHGVPYEANNRAVPDKIDWRESGYVTEVKDQGNCGSCWAFST 137 + R + + YEA P +DWRE GYVT VK+QG CGS WAFS Sbjct: 68 RQVMNGLQNRKPRKGKVFQEPLFYEA-----PRSVDWREKGYVTPVKNQGQCGSSWAFSA 122 Query: 138 TGTMEGQYMKNERTSISFSEQQLVDCSGPWGNNGCSGGLMENAYQYLKQF-GLETESSYP 196 TG +EGQ + IS SEQ LVDCSGP GN GC+GGLM+ A+QY++ GL++E SYP Sbjct: 123 TGALEGQMFRKTGRLISLSEQNLVDCSGPEGNEGCNGGLMDYAFQYVQDNGGLDSEESYP 182 Query: 197 YTAVEGQCRYNKQLGVAKVTGYYTVHSGSEVELKNLVGARRPAAVAVDV-ESDFMMYRSG 255 Y A E C+YN + VA G+ + E L V P +VA+D F+ Y+ G Sbjct: 183 YEATEESCKYNPKYSVANDAGFVDIPK-QEKALMKAVATVGPISVAIDAGHESFLFYKEG 241 Query: 256 IYQSQTCSPLRVNHAVLAVGYGTQG----GTDYWIVKNSWGTYWGERGYIRMARNRGNMC 311 IY CS ++H VL VGYG + G YW+VKNSWG WG GY++MA++R N C Sbjct: 242 IYFEPDCSSEDMDHGVLVVGYGFESTESDGNKYWLVKNSWGEEWGMGGYVKMAKDRRNHC 301 Query: 312 GIASLASLPMV 322 GIAS AS P V Sbjct: 302 GIASAASYPTV 312 >3QJ3-A nrPDB Length = 331 Score = 246 bits (627), Expect = 1e-65, Method: Compositional matrix adjust. Identities = 133/314 (42%), Positives = 188/314 (59%), Gaps = 16/314 (5%) Query: 21 WHQWKRMYNKEY-NGADDQHRRNIWEKNVKHIQEHNLRHDLGLVTYTLGLNQFTDMTFEE 79 W +K Y + Y N ++ R+ I++K ++ +EHN ++ GLV+YTLG+N FTDMT EE Sbjct: 22 WENFKTTYARSYVNAKEETFRKQIFQKKLETFEEHNEKYRQGLVSYTLGVNLFTDMTPEE 81 Query: 80 FKAKYLTEMSRASDILSHGVPYEAN-----NRAV--PDKIDWRESGYVTEVKDQGNCGSC 132 KA Y + +D+ +G+P + N +V P DWR+ G V+ VK+QG+CGS Sbjct: 82 MKA-YTHGLIMPADLHKNGIPIKTREDLGLNASVRYPASFDWRDQGMVSPVKNQGSCGSS 140 Query: 133 WAFSTTGTMEGQYMKNERTS---ISFSEQQLVDCSGPWGNNGCSGGLMENAYQYLKQFG- 188 WAFS+TG +E Q MK + S SEQQLVDC GCSGG M +A+ Y+ Q G Sbjct: 141 WAFSSTGAIESQ-MKIANGAGYDSSVSEQQLVDCVP--NALGCSGGWMNDAFTYVAQNGG 197 Query: 189 LETESSYPYTAVEGQCRYNKQLGVAKVTGYYTVHSGSEVELKNLVGARRPAAVAVDVESD 248 +++E +YPY +G C Y+ A+++GY + E L ++V + P AVA D + Sbjct: 198 IDSEGAYPYEMADGNCHYDPNQVAARLSGYVYLSGPDENMLADMVATKGPVAVAFDADDP 257 Query: 249 FMMYRSGIYQSQTCSPLRVNHAVLAVGYGTQGGTDYWIVKNSWGTYWGERGYIRMARNRG 308 F Y G+Y + TC + HAVL VGYG + G DYW+VKNSWG WG GY ++ARN Sbjct: 258 FGSYSGGVYYNPTCETNKFTHAVLIVGYGNENGQDYWLVKNSWGDGWGLDGYFKIARNAN 317 Query: 309 NMCGIASLASLPMV 322 N CGIA +AS+P + Sbjct: 318 NHCGIAGVASVPTL 331 >3HWN-A nrPDB Length = 258 Score = 229 bits (584), Expect = 1e-60, Method: Compositional matrix adjust. Identities = 122/263 (46%), Positives = 154/263 (58%), Gaps = 15/263 (5%) Query: 69 LNQFTDMTFEEFKA---KYLTEMSRASDILSHGVPYEANNRAVPDKIDWRESGYVTEVKD 125 +N F DMT EEF+ + R + + YEA P +DWRE GYVT VK+ Sbjct: 2 MNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEA-----PRSVDWREKGYVTPVKN 56 Query: 126 QGNCGSCWAFSTTGTMEGQYMKNERTSISFSEQQLVDCSGPWGNNGCSGGLMENAYQYLK 185 QG CGSCWAFS TG +EGQ + IS SEQ LVDCSGP GN GC+GGLM+ A+QY++ Sbjct: 57 QGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQ 116 Query: 186 Q-FGLETESSYPYTAVEGQCRYNKQLGVAKVTGYYTVHSGSEVELKNLVGARRPAAVAVD 244 GL++E SYPY A E C+YN + VA G+ + E L V P +VA+D Sbjct: 117 DNGGLDSEESYPYEATEESCKYNPKYSVANDAGFVDIPK-QEKALMKAVATVGPISVAID 175 Query: 245 V-ESDFMMYRSGIYQSQTCSPLRVNHAVLAVGYGTQG----GTDYWIVKNSWGTYWGERG 299 F+ Y+ GIY CS ++H VL VGYG + YW+VKNSWG WG G Sbjct: 176 AGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGG 235 Query: 300 YIRMARNRGNMCGIASLASLPMV 322 Y++MA++R N CGIAS AS P V Sbjct: 236 YVKMAKDRRNHCGIASAASYPTV 258 >6CZS-A nrPDB Length = 335 Score = 221 bits (563), Expect = 3e-58, Method: Compositional matrix adjust. Identities = 126/305 (41%), Positives = 171/305 (56%), Gaps = 17/305 (5%) Query: 24 WKRMYNKEYNGADDQHRRNIWEKNVKHIQEHNLRHDLGLVTYTLGLNQFTDMTFEEFKAK 83 W + K Y+ + HR + N + I HN G T+ + LNQF+DM+F E K K Sbjct: 38 WMSKHRKTYSTEEYHHRLQTFASNWRKINAHNN----GNHTFKMALNQFSDMSFAEIKHK 93 Query: 84 YL-TEMSRASDILSHGVPYEANNRAVPDKIDWRESG-YVTEVKDQGNCGSCWAFSTTGTM 141 YL +E S S+ Y P +DWR+ G +V+ VK+QG CGS W FSTTG + Sbjct: 94 YLWSEPQNCSATKSN---YLRGTGPYPPSVDWRKKGNFVSPVKNQGACGSSWTFSTTGAL 150 Query: 142 EGQYMKNERTSISFSEQQLVDCSGPWGNNGCSGGLMENAYQY-LKQFGLETESSYPYTAV 200 E +S +EQQLVDC+ + N+GC GGL A++Y L G+ E +YPY Sbjct: 151 ESAIAIATGKMLSLAEQQLVDCAQDFNNHGCQGGLPSQAFEYILYNKGIMGEDTYPYQGK 210 Query: 201 EGQCRYN--KQLGVAKVTGYYTVHSGSEVELKNLVGARRPAAVAVDVESDFMMYRSGIYQ 258 +G C++ K +G K T++ E + V P + A +V DFMMYR+GIY Sbjct: 211 DGYCKFQPGKAIGFVKDVANITIY--DEEAMVEAVALYNPVSFAFEVTQDFMMYRTGIYS 268 Query: 259 SQTC--SPLRVNHAVLAVGYGTQGGTDYWIVKNSWGTYWGERGYIRMARNRGNMCGIASL 316 S +C +P +VNHAVLAVGYG + G YWIVKNSWG WG GY + R + NMCG+A+ Sbjct: 269 STSCHKTPDKVNHAVLAVGYGEKNGIPYWIVKNSWGPQWGMNGYFLIERGK-NMCGLAAC 327 Query: 317 ASLPM 321 AS P+ Sbjct: 328 ASYPI 332 >3KFQ-A nrPDB Length = 221 Score = 220 bits (561), Expect = 5e-58, Method: Compositional matrix adjust. Identities = 108/221 (48%), Positives = 141/221 (63%), Gaps = 6/221 (2%) Query: 108 VPDKIDWRESGYVTEVKDQGNCGSCWAFSTTGTMEGQYMKNERTSISFSEQQLVDCSGPW 167 +P +DWR+ GYVT VK+Q CGSCWAFS TG +EGQ + +S SEQ LVDCS P Sbjct: 1 LPKSVDWRKKGYVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQ 60 Query: 168 GNNGCSGGLMENAYQYLKQ-FGLETESSYPYTAVEGQCRYNKQLGVAKVTGYYTVHSGSE 226 GN GC+GG M A+QY+K+ GL++E SYPY AV+ C+Y + VA+ TG+ V G E Sbjct: 61 GNQGCNGGFMARAFQYVKENGGLDSEESYPYVAVDEICKYRPENSVAQDTGFTVVAPGKE 120 Query: 227 VELKNLVGARRPAAVAVDV-ESDFMMYRSGIYQSQTCSPLRVNHAVLAVGYGTQGG---- 281 L V P +VA+D S F Y+SGIY CS ++H VL VGYG +G Sbjct: 121 KALMKAVATVGPISVAMDAGHSSFQFYKSGIYFEPDCSSKNLDHGVLVVGYGFEGANSDN 180 Query: 282 TDYWIVKNSWGTYWGERGYIRMARNRGNMCGIASLASLPMV 322 + YW+VKNSWG WG GY+++A+++ N CGIA+ AS P V Sbjct: 181 SKYWLVKNSWGPEWGSNGYVKIAKDKNNHCGIATAASYPNV 221 >3OF9-A nrPDB Length = 221 Score = 218 bits (556), Expect = 2e-57, Method: Compositional matrix adjust. Identities = 111/221 (50%), Positives = 138/221 (62%), Gaps = 7/221 (3%) Query: 108 VPDKIDWRESGYVTEVKDQGNCGSCWAFSTTGTMEGQYMKNERTSISFSEQQLVDCSGPW 167 P +DWRE GYVT VK+QG CGSCWAFS TG +EGQ + IS SEQ LVDCSGP Sbjct: 2 APRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQ 61 Query: 168 GNNGCSGGLMENAYQYLKQ-FGLETESSYPYTAVEGQCRYNKQLGVAKVTGYYTVHSGSE 226 GN GC+GGLM+ A+QY++ GL++E SYPY A E C+YN + VA TG+ + E Sbjct: 62 GNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPK-QE 120 Query: 227 VELKNLVGARRPAAVAVDV-ESDFMMYRSGIYQSQTCSPLRVNHAVLAVGYGTQG----G 281 L V P +VA+D F+ Y+ GIY CS ++H VL VGYG + Sbjct: 121 KALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDN 180 Query: 282 TDYWIVKNSWGTYWGERGYIRMARNRGNMCGIASLASLPMV 322 YW+VKNSWG WG GY++MA++R N CGIAS AS P V Sbjct: 181 NKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV 221 >4BS5-A nrPDB Length = 225 Score = 218 bits (554), Expect = 4e-57, Method: Compositional matrix adjust. Identities = 110/223 (49%), Positives = 140/223 (62%), Gaps = 5/223 (2%) Query: 104 NNRAVPDKIDWRESGYVTEVKDQGNCGSCWAFSTTGTMEGQYMKNERTSISFSEQQLVDC 163 +NR +PD +DWRE G VTEVK QG+CG+CWAFS G +EGQ IS S Q LVDC Sbjct: 4 SNRTLPDTVDWREKGCVTEVKYQGSCGACWAFSAVGALEGQLKLKTGKLISLSAQNLVDC 63 Query: 164 SG--PWGNNGCSGGLMENAYQYL-KQFGLETESSYPYTAVEGQCRYNKQLGVAKVTGYYT 220 S +GN GC GG M A+QY+ G+E ++SYPY A++ +C YN + A + Y Sbjct: 64 SNEEKYGNKGCGGGYMTEAFQYIIDNGGIEADASYPYKAMDEKCHYNSKNRAATCSRYIQ 123 Query: 221 VHSGSEVELKNLVGARRPAAVAVDV-ESDFMMYRSGIYQSQTCSPLRVNHAVLAVGYGTQ 279 + G E LK V + P +V +D S F Y+SG+Y +C+ VNH VL VGYGT Sbjct: 124 LPFGDEDALKEAVATKGPVSVGIDASHSSFFFYKSGVYDDPSCTG-NVNHGVLVVGYGTL 182 Query: 280 GGTDYWIVKNSWGTYWGERGYIRMARNRGNMCGIASLASLPMV 322 G DYW+VKNSWG +G++GYIRMARN N CGIAS S P + Sbjct: 183 DGKDYWLVKNSWGLNFGDQGYIRMARNNKNHCGIASYCSYPEI 225 >4P6E-A nrPDB Length = 230 Score = 215 bits (548), Expect = 2e-56, Method: Compositional matrix adjust. Identities = 107/221 (48%), Positives = 141/221 (63%), Gaps = 4/221 (1%) Query: 105 NRAVPDKIDWRESGYVTEVKDQGNCGSCWAFSTTGTMEGQYMKNERTSISFSEQQLVDCS 164 NR +PD +DWRE G VTEVK QG+CG+CWAFS G +E Q +S S Q LVDCS Sbjct: 4 NRILPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCS 63 Query: 165 G-PWGNNGCSGGLMENAYQYL-KQFGLETESSYPYTAVEGQCRYNKQLGVAKVTGYYTVH 222 +GN GC+GG M A+QY+ G+++++SYPY A++ +C+Y+ + A + Y + Sbjct: 64 TEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELP 123 Query: 223 SGSEVELKNLVGARRPAAVAVDV-ESDFMMYRSGIYQSQTCSPLRVNHAVLAVGYGTQGG 281 G E LK V + P +V VD F +YRSG+Y +C+ VNH VL VGYG G Sbjct: 124 YGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCT-QNVNHGVLVVGYGDLNG 182 Query: 282 TDYWIVKNSWGTYWGERGYIRMARNRGNMCGIASLASLPMV 322 +YW+VKNSWG +GE GYIRMARN+GN CGIAS S P + Sbjct: 183 KEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIASFPSYPEI 223 >5JA7-A nrPDB Length = 223 Score = 214 bits (544), Expect = 5e-56, Method: Compositional matrix adjust. Identities = 105/217 (48%), Positives = 136/217 (62%), Gaps = 4/217 (1%) Query: 108 VPDKIDWRESGYVTEVKDQGNCGSCWAFSTTGTMEGQYMKNERTSISFSEQQLVDCSGPW 167 PD +D+R+ GYVT VK+QG CGS WAFS+ G +EGQ K ++ S Q LVDC Sbjct: 9 APDSVDYRKKGYVTPVKNQGQCGSSWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSE- 67 Query: 168 GNNGCSGGLMENAYQYL-KQFGLETESSYPYTAVEGQCRYNKQLGVAKVTGYYTVHSGSE 226 N+GC GG M NA+QY+ K G+++E +YPY E C YN AK GY + G+E Sbjct: 68 -NDGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNE 126 Query: 227 VELKNLVGARRPAAVAVDVE-SDFMMYRSGIYQSQTCSPLRVNHAVLAVGYGTQGGTDYW 285 LK V P +VA+D + F Y G+Y ++C+ +NHAVLAVGYG Q G +W Sbjct: 127 KALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHW 186 Query: 286 IVKNSWGTYWGERGYIRMARNRGNMCGIASLASLPMV 322 I+KNSWG WG +GYI MARN+ N CGIA+LAS P + Sbjct: 187 IIKNSWGENWGNKGYILMARNKNNACGIANLASFPKM 223 >6BKI-A nrPDB Length = 215 Score = 208 bits (530), Expect = 2e-54, Method: Compositional matrix adjust. Identities = 102/215 (47%), Positives = 133/215 (61%), Gaps = 4/215 (1%) Query: 108 VPDKIDWRESGYVTEVKDQGNCGSCWAFSTTGTMEGQYMKNERTSISFSEQQLVDCSGPW 167 VPD ID+R+ GYVT VK+QG CGSCWAFS+ G +EGQ K ++ S Q LVDC Sbjct: 1 VPDSIDYRKKGYVTPVKNQGQCGSCWAFSSAGALEGQLKKKTGKLLALSPQNLVDCVTE- 59 Query: 168 GNNGCSGGLMENAYQYLKQ-FGLETESSYPYTAVEGQCRYNKQLGVAKVTGYYTVHSGSE 226 N GC GG M A+QY++Q G+++E +YPY + C YN AK GY + G+E Sbjct: 60 -NYGCGGGYMTTAFQYVQQNGGIDSEDAYPYVGQDESCMYNAAAKAAKCRGYREIPVGNE 118 Query: 227 VELKNLVGARRPAAVAVDVE-SDFMMYRSGIYQSQTCSPLRVNHAVLAVGYGTQGGTDYW 285 LK V P +V++D + F Y G+Y + C VNHAVL VGYGTQ G+ +W Sbjct: 119 KALKRAVARVGPISVSIDASLASFQFYSRGVYYDENCDRDNVNHAVLVVGYGTQKGSKHW 178 Query: 286 IVKNSWGTYWGERGYIRMARNRGNMCGIASLASLP 320 I+KNSWG WG +GY +ARN+ N CGI ++AS P Sbjct: 179 IIKNSWGESWGNKGYALLARNKNNACGITNMASFP 213 >2VHS-A nrPDB Length = 217 Score = 206 bits (525), Expect = 8e-54, Method: Compositional matrix adjust. Identities = 109/218 (50%), Positives = 137/218 (62%), Gaps = 4/218 (1%) Query: 108 VPDKIDWRESGYVTEVKDQGNCGSCWAFSTTGTMEGQYMKNERTSISFSEQQLVDCSGPW 167 P +DWRE GYVT VK+QG CG+ +AFS TG +EGQ + IS SEQ LVDCSGP Sbjct: 1 APRSVDWREKGYVTPVKNQGQCGASYAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQ 60 Query: 168 GNNGCSGGLMENAYQYLKQ-FGLETESSYPYTAVEGQCRYNKQLGVAKVTGYYTVHSGSE 226 GN GC+GGLM+ A+QY++ GL++E SYPY A E C+YN + VA G+ + E Sbjct: 61 GNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDVGFVDIPK-QE 119 Query: 227 VELKNLVGARRPAAVAVDV-ESDFMMYRSGIYQSQTCSPLRVNHAVLAVGYG-TQGGTDY 284 L V P +VA+D F+ Y+ GIY S CS +NHA+L VGYG Y Sbjct: 120 KALMKAVATVGPISVAIDAGHESFLFYKEGIYFSSDCSSSSLNHAMLVVGYGFISNNQKY 179 Query: 285 WIVKNSWGTYWGERGYIRMARNRGNMCGIASLASLPMV 322 W+VKNSWG WG GY++MA++R N CGIAS AS P V Sbjct: 180 WLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV 217 >1NB3-A nrPDB Length = 220 Score = 194 bits (493), Expect = 5e-50, Method: Compositional matrix adjust. Identities = 95/217 (43%), Positives = 132/217 (60%), Gaps = 5/217 (2%) Query: 109 PDKIDWRESG-YVTEVKDQGNCGSCWAFSTTGTMEGQYMKNERTSISFSEQQLVDCSGPW 167 P +DWR+ G +V+ VK+QG+CGSCW FSTTG +E +S +EQQLVDC+ + Sbjct: 2 PPSMDWRKKGNFVSPVKNQGSCGSCWTFSTTGALESAVAIATGKMLSLAEQQLVDCAQNF 61 Query: 168 GNNGCSGGLMENAYQYLK-QFGLETESSYPYTAVEGQCRYNKQLGVAKVTGYYTVHSGSE 226 N+GC GGL A++Y++ G+ E +YPY + C++ +A V + E Sbjct: 62 NNHGCQGGLPSQAFEYIRYNKGIMGEDTYPYKGQDDHCKFQPDKAIAFVKDVANITMNDE 121 Query: 227 VELKNLVGARRPAAVAVDVESDFMMYRSGIYQSQTC--SPLRVNHAVLAVGYGTQGGTDY 284 + V P + A +V +DF+MYR GIY S +C +P +VNHAVLAVGYG + G Y Sbjct: 122 EAMVEAVALYNPVSFAFEVTNDFLMYRKGIYSSTSCHKTPDKVNHAVLAVGYGEENGIPY 181 Query: 285 WIVKNSWGTYWGERGYIRMARNRGNMCGIASLASLPM 321 WIVKNSWG WG GY + R + NMCG+A+ AS P+ Sbjct: 182 WIVKNSWGPQWGMNGYFLIERGK-NMCGLAACASYPI 217 >3P5W-A nrPDB Length = 220 Score = 186 bits (473), Expect = 8e-48, Method: Compositional matrix adjust. Identities = 103/219 (47%), Positives = 134/219 (61%), Gaps = 8/219 (3%) Query: 108 VPDKIDWRESGYVTEVKDQGNCGSCWAFSTTGTMEGQYMKNERTSISFSEQQLVDCSGPW 167 +PD +DWR SG V ++KDQG CGSCWAFST +EG IS SEQ+LVDC Sbjct: 1 LPDYVDWRSSGAVVDIKDQGQCGSCWAFSTIAAVEGINKIATGDLISLSEQELVDCGRTQ 60 Query: 168 GNNGCSGGLMENAYQYL-KQFGLETESSYPYTAVEGQCRYN-KQLGVAKVTGYYTVHSGS 225 GC GG M + +Q++ G+ TE++YPYTA EGQC + +Q + Y V + Sbjct: 61 NTRGCDGGFMTDGFQFIINNGGINTEANYPYTAEEGQCNLDLQQEKYVSIDTYENVPYNN 120 Query: 226 EVELKNLVGARRPAAVAVDVES-DFMMYRSGIYQSQTCSPLRVNHAVLAVGYGTQGGTDY 284 E L+ V A +P +VA++ +F Y SGI+ + V+HAV VGYGT+GG DY Sbjct: 121 EWALQTAV-AYQPVSVALEAAGYNFQHYSSGIFTGPCGTA--VDHAVTIVGYGTEGGIDY 177 Query: 285 WIVKNSWGTYWGERGYIRMARNRGNM--CGIASLASLPM 321 WIVKNSWGT WGE GY+R+ RN G + CGIA AS P+ Sbjct: 178 WIVKNSWGTTWGEEGYMRIQRNVGGVGQCGIAKKASYPV 216 >2PNS-A nrPDB Length = 208 Score = 183 bits (465), Expect = 7e-47, Method: Compositional matrix adjust. Identities = 108/219 (49%), Positives = 137/219 (62%), Gaps = 14/219 (6%) Query: 108 VPDKIDWRESGYVTEVKDQGNCGSCWAFSTTGTMEGQYMKNERTSISFSEQQLVDCSGPW 167 +P++IDWR+ G VT VK+QG CGSCWAFST T+E IS SEQQLVDC+ Sbjct: 1 LPEQIDWRKKGAVTPVKNQGKCGSCWAFSTVSTVESINQIRTGNLISLSEQQLVDCNKK- 59 Query: 168 GNNGCSGGLMENAYQY-LKQFGLETESSYPYTAVEGQCRYNKQLGVAKVTGYYTVHSGSE 226 N+GC GG AYQY + G++TE++YPY AV+G CR K+ V ++ GY V +E Sbjct: 60 -NHGCKGGAFVYAYQYIIDNGGIDTEANYPYKAVQGPCRAAKK--VVRIDGYKGVPHCNE 116 Query: 227 VELKNLVGARRPAAVAVDVES-DFMMYRSGIYQSQTCSPLRVNHAVLAVGYGTQGGTDYW 285 LK V A +P+ VA+D S F Y+SGI+ S C ++NH V+ VGY DYW Sbjct: 117 NALKKAV-ASQPSVVAIDASSKQFQHYKSGIF-SGPCG-TKLNHGVVIVGY----WKDYW 169 Query: 286 IVKNSWGTYWGERGYIRMARNRG-NMCGIASLASLPMVA 323 IV+NSWG YWGE+GYIRM R G +CGIA L P A Sbjct: 170 IVRNSWGRYWGEQGYIRMKRVGGCGLCGIARLPYYPTKA 208 >1CQD-A nrPDB Length = 221 Score = 182 bits (463), Expect = 1e-46, Method: Compositional matrix adjust. Identities = 101/219 (46%), Positives = 130/219 (59%), Gaps = 10/219 (4%) Query: 108 VPDKIDWRESGYVTEVKDQGNCGSCWAFSTTGTMEGQYMKNERTSISFSEQQLVDCSGPW 167 +PD IDWRE+G V VK+QG CGSCWAFST +EG IS SEQQLVDC+ Sbjct: 3 LPDSIDWRENGAVVPVKNQGGCGSCWAFSTVAAVEGINQIVTGDLISLSEQQLVDCTT-- 60 Query: 168 GNNGCSGGLMENAYQYL-KQFGLETESSYPYTAVEGQCRYNKQLGVAKVTGYYTVHSGSE 226 N+GC GG M A+Q++ G+ +E +YPY +G C V + Y V S +E Sbjct: 61 ANHGCRGGWMNPAFQFIVNNGGINSEETYPYRGQDGICNSTVNAPVVSIDSYENVPSHNE 120 Query: 227 VELKNLVGARRPAAVAVDVES-DFMMYRSGIYQSQTCSPLRVNHAVLAVGYGTQGGTDYW 285 L+ V A +P +V +D DF +YRSGI+ + +C+ + NHA+ VGYGT+ D+W Sbjct: 121 QSLQKAV-ANQPVSVTMDAAGRDFQLYRSGIF-TGSCN-ISANHALTVVGYGTENDKDFW 177 Query: 286 IVKNSWGTYWGERGYIRMARNRGN---MCGIASLASLPM 321 IVKNSWG WGE GYIR RN N CGI AS P+ Sbjct: 178 IVKNSWGKNWGESGYIRAERNIENPDGKCGITRFASYPV 216 >5EF4-A nrPDB Length = 385 Score = 179 bits (455), Expect = 1e-45, Method: Compositional matrix adjust. Identities = 114/319 (35%), Positives = 153/319 (47%), Gaps = 28/319 (8%) Query: 20 LWHQWKRMYNKEYNGADDQHRRNIWEKNVKHIQEHNLRHDLGLVTYTLGLNQFTDMTFEE 79 ++ +W+ +N E + R N+++ NV+ I E N Y L +N+F DMT E Sbjct: 38 MYDRWREQHNIEMRSPE---RFNVFKYNVRRIHESNKMDK----PYKLKVNEFADMTNLE 90 Query: 80 FKAKYLTEMSRASDILSHGVPYE-----------ANNRAVPDKIDWRESGYVTEVKDQGN 128 F Y L P AN +PDK+DWRE VT+VK QG Sbjct: 91 FVNTYANSKISHFQALRGSAPGSIDTDPNKDFIYANVTKIPDKVDWREKNAVTDVKGQGG 150 Query: 129 CGSCWAFSTTGTMEGQYMKNERTSISFSEQQLVDCSGPWGNNGCSGGLMENAYQY-LKQF 187 CGSCWAF+ +EG + FSEQQLVDC N GC GGLME A+ Y +K Sbjct: 151 CGSCWAFAAVVALEGINAIRTGKLVKFSEQQLVDCD--MTNAGCDGGLMEPAFTYVIKHG 208 Query: 188 GLETESSYPYTAVEGQCRYNKQLGVAKVTGYYTVHSGSEVELKNLVGARRPAAVAVDVES 247 G+ E+SYPY C K V K+ G V E L+ V A +P A + + Sbjct: 209 GIAPEASYPYVGKRETCDKAKIKDVLKIDGRQNVPGLDEEALRKAV-AHQPVATGIQLSG 267 Query: 248 D-FMMYRSGIYQSQTCSPLRVNHAVLAVGYG-TQGGTDYWIVKNSWGTYWGERGYIRMAR 305 Y G+Y + NH V VGYG + G +W VKNSWG WGE+GYI + R Sbjct: 268 HGLQFYSEGVYTGDCGT--EPNHGVGIVGYGENEKGIKFWTVKNSWGPTWGEKGYIHLQR 325 Query: 306 --NRGNMCGIASLASLPMV 322 + +CG+A +S P++ Sbjct: 326 GARKEGLCGVAMHSSFPIM 344 >1PCI-A nrPDB Length = 322 Score = 179 bits (454), Expect = 2e-45, Method: Compositional matrix adjust. Identities = 114/302 (37%), Positives = 176/302 (58%), Gaps = 15/302 (4%) Query: 20 LWHQWKRMYNKEYNGADDQ-HRRNIWEKNVKHIQEHNLRHDLGLVTYTLGLNQFTDMTFE 78 L++ W +NK Y D++ +R I++ N+ +I E N +++ +Y LGLN+F D++ + Sbjct: 21 LFNSWMLNHNKFYENVDEKLYRFEIFKDNLNYIDETNKKNN----SYWLGLNEFADLSND 76 Query: 79 EFKAKYLTEMSRASDILSHGVPYEANNRA-VPDKIDWRESGYVTEVKDQGNCGSCWAFST 137 EF KY+ + A+ S+ + + +P+ +DWR+ G VT V+ QG+CGSCWAFS Sbjct: 77 EFNEKYVGSLIDATIEQSYDEEFINEDIVNLPENVDWRKKGAVTPVRHQGSCGSCWAFSA 136 Query: 138 TGTMEGQYMKNERTSISFSEQQLVDCSGPWGNNGCSGGLMENAYQYLKQFGLETESSYPY 197 T+EG + SEQ+LVDC ++GC GG A +Y+ + G+ S YPY Sbjct: 137 VATVEGINKIRTGKLVELSEQELVDCE--RRSHGCKGGYPPYALEYVAKNGIHLRSKYPY 194 Query: 198 TAVEGQCRYNKQLG--VAKVTGYYTVHSGSEVELKNLVGARRPAAVAVDVES-DFMMYRS 254 A +G CR KQ+G + K +G V +E L N + A++P +V V+ + F +Y+ Sbjct: 195 KAKQGTCRA-KQVGGPIVKTSGVGRVQPNNEGNLLNAI-AKQPVSVVVESKGRPFQLYKG 252 Query: 255 GIYQSQTCSPLRVNHAVLAVGYGTQGGTDYWIVKNSWGTYWGERGYIRMARNRGNMCGIA 314 GI++ + +V+ AV AVGYG GG Y ++KNSWGT WGE+GYIR+ R GN G+ Sbjct: 253 GIFEGPCGT--KVDGAVTAVGYGKSGGKGYILIKNSWGTAWGEKGYIRIKRAPGNSPGVC 310 Query: 315 SL 316 L Sbjct: 311 GL 312 >1S4V-A nrPDB Length = 229 Score = 179 bits (453), Expect = 2e-45, Method: Compositional matrix adjust. Identities = 102/221 (46%), Positives = 133/221 (60%), Gaps = 11/221 (4%) Query: 108 VPDKIDWRESGYVTEVKDQGNCGSCWAFSTTGTMEGQYMKNERTSISFSEQQLVDCSGPW 167 VP +DWR+ G VT VKDQG CGSCWAFST +EG +S SEQ+LVDC Sbjct: 2 VPASVDWRKKGAVTSVKDQGQCGSCWAFSTIVAVEGINQIKTNKLVSLSEQELVDCDTDQ 61 Query: 168 GNNGCSGGLMENAYQYLKQ-FGLETESSYPYTAVEGQCRYNKQLGVA-KVTGYYTVHSGS 225 N GC+GGLM+ A++++KQ G+ TE++YPY A +G C +K+ A + G+ V Sbjct: 62 -NQGCNGGLMDYAFEFIKQRGGITTEANYPYEAYDGTCDVSKENAPAVSIDGHENVPEND 120 Query: 226 EVELKNLVGARRPAAVAVDV-ESDFMMYRSGIYQSQTCSPLRVNHAVLAVGYGTQ-GGTD 283 E L V A +P +VA+D SDF Y G++ + L +H V VGYGT GT Sbjct: 121 ENALLKAV-ANQPVSVAIDAGGSDFQFYSEGVFTGSCGTEL--DHGVAIVGYGTTIDGTK 177 Query: 284 YWIVKNSWGTYWGERGYIRMAR---NRGNMCGIASLASLPM 321 YW VKNSWG WGE+GYIRM R ++ +CGIA AS P+ Sbjct: 178 YWTVKNSWGPEWGEKGYIRMERGISDKEGLCGIAMEASYPI 218 >3F75-A nrPDB Length = 224 Score = 176 bits (447), Expect = 9e-45, Method: Compositional matrix adjust. Identities = 94/221 (42%), Positives = 133/221 (60%), Gaps = 9/221 (4%) Query: 108 VPDKIDWRESGYVTEVKDQGNCGSCWAFSTTGTMEGQYMKNERTSISFSEQQLVDCSGPW 167 +P +DWR G VT VKDQ +CGSCWAFSTTG +EG + +S SEQ+L+DCS Sbjct: 7 LPAGVDWRSRGCVTPVKDQRDCGSCWAFSTTGALEGAHCAKTGKLVSLSEQELMDCSRAE 66 Query: 168 GNNGCSGGLMENAYQY-LKQFGLETESSYPYTAVEGQCRYNKQLGVAKVTGYYTVHSGSE 226 GN CSGG M +A+QY L G+ +E +YPY A + +CR V K+ G+ V SE Sbjct: 67 GNQSCSGGEMNDAFQYVLDSGGICSEDAYPYLARDEECRAQSCEKVVKILGFKDVPRRSE 126 Query: 227 VELKNLVGARRPAAVAVDVES-DFMMYRSGIYQSQTCSPLRVNHAVLAVGYGT--QGGTD 283 +K + A+ P ++A++ + F Y G++ + + L +H VL VGYGT + D Sbjct: 127 AAMKAAL-AKSPVSIAIEADQMPFQFYHEGVFDASCGTDL--DHGVLLVGYGTDKESKKD 183 Query: 284 YWIVKNSWGTYWGERGYIRMARNRGN--MCGIASLASLPMV 322 +WI+KNSWGT WG GY+ MA ++G CG+ AS P++ Sbjct: 184 FWIMKNSWGTGWGRDGYMYMAMHKGEEGQCGLLLDASFPVM 224 >3BCN-A nrPDB Length = 209 Score = 176 bits (447), Expect = 1e-44, Method: Compositional matrix adjust. Identities = 101/219 (46%), Positives = 132/219 (60%), Gaps = 14/219 (6%) Query: 108 VPDKIDWRESGYVTEVKDQGNCGSCWAFSTTGTMEGQYMKNERTSISFSEQQLVDCSGPW 167 +P+ +DWR G V +K+QG CGSCWAFST T+E IS SEQQLVDCS Sbjct: 1 LPEHVDWRAKGAVIPLKNQGKCGSCWAFSTVTTVESINQIRTGNLISLSEQQLVDCSKK- 59 Query: 168 GNNGCSGGLMENAYQY-LKQFGLETESSYPYTAVEGQCRYNKQLGVAKVTGYYTVHSGSE 226 N+GC GG + AYQY + G++TE++YPY A +G CR K+ V ++ G V +E Sbjct: 60 -NHGCKGGYFDRAYQYIIANGGIDTEANYPYKAFQGPCRAAKK--VVRIDGCKGVPQCNE 116 Query: 227 VELKNLVGARRPAAVAVDVES-DFMMYRSGIYQSQTCSPLRVNHAVLAVGYGTQGGTDYW 285 LKN V A +P+ VA+D S F Y+ GI+ + ++NH V+ VGY G DYW Sbjct: 117 NALKNAV-ASQPSVVAIDASSKQFQHYKGGIFTGPCGT--KLNHGVVIVGY----GKDYW 169 Query: 286 IVKNSWGTYWGERGYIRMARNRG-NMCGIASLASLPMVA 323 IV+NSWG +WGE+GY RM R G +CGIA L P A Sbjct: 170 IVRNSWGRHWGEQGYTRMKRVGGCGLCGIARLPFYPTKA 208 >4YYR-A nrPDB Length = 222 Score = 176 bits (445), Expect = 2e-44, Method: Compositional matrix adjust. Identities = 97/222 (43%), Positives = 138/222 (62%), Gaps = 13/222 (5%) Query: 108 VPDKIDWRESGYVTEVKDQGNCGSCWAFSTTGTMEGQYMKNERTSISFSEQQLVDCSGPW 167 +P+ +DWR G V +++QG CGSCWAFS +EG S SEQQLVDC+ + Sbjct: 1 LPETVDWRIQGAVNPIRNQGRCGSCWAFSVVVVVEGITKIVTDELPSLSEQQLVDCATSY 60 Query: 168 GNNGCSGGLMENAYQYL-KQFGLETESSYPYTAVEGQCRYNKQLG---VAKVTGYYTVHS 223 N GCSGG M AY Y+ K G+ ++S+YPYTA +G+C NK L VA + Y V Sbjct: 61 KNLGCSGGWMTKAYDYIIKNGGITSQSNYPYTAKKGEC--NKDLASQIVATIDSYEHVPR 118 Query: 224 GSEVELKNLVGARRPAAVAVDVES-DFMMYRSGIYQSQTCSPLRVNHAVLAVGYGTQGGT 282 +E LKN V A +P +V ++ F +Y+SG++ +C +++HAV+A+GYG++ Sbjct: 119 NNENALKNAV-ANQPVSVTIEAGGRAFELYKSGVFVG-SCG-TKLDHAVVAIGYGSENDV 175 Query: 283 DYWIVKNSWGTYWGERGYIRMARNRGN---MCGIASLASLPM 321 DYW+V+NSWGT WGERGYI++ RN CGIA ++ P+ Sbjct: 176 DYWLVRNSWGTNWGERGYIKLQRNVAEPTGKCGIAMQSTYPV 217 >2FO5-A nrPDB Length = 262 Score = 175 bits (443), Expect = 3e-44, Method: Compositional matrix adjust. Identities = 98/224 (43%), Positives = 134/224 (59%), Gaps = 14/224 (6%) Query: 108 VPDKIDWRESGYVTEVKDQGNCGSCWAFSTTGTMEGQYMKNERTSISFSEQQLVDCSGPW 167 +P +DWR+ G VT VKDQG CGSCWAFST ++EG + +S SEQ+L+DC Sbjct: 4 LPPSVDWRQKGAVTGVKDQGKCGSCWAFSTVVSVEGINAIRTGSLVSLSEQELIDCDTA- 62 Query: 168 GNNGCSGGLMENAYQYLK-QFGLETESSYPYTAVEGQCRYNKQLG----VAKVTGYYTVH 222 N+GC GGLM+NA++Y+K GL TE++YPY A G C + V + G+ V Sbjct: 63 DNDGCQGGLMDNAFEYIKNNGGLITEAAYPYRAARGTCNVARAAQNSPVVVHIDGHQDVP 122 Query: 223 SGSEVELKNLVGARRPAAVAVDVESD-FMMYRSGIYQSQTCSPLRVNHAVLAVGYG-TQG 280 + SE +L V A +P +VAV+ FM Y G++ + + L +H V VGYG + Sbjct: 123 ANSEEDLARAV-ANQPVSVAVEASGKAFMFYSEGVFTGECGTEL--DHGVAVVGYGVAED 179 Query: 281 GTDYWIVKNSWGTYWGERGYIRMARN---RGNMCGIASLASLPM 321 G YW VKNSWG WGE+GYIR+ ++ G +CGIA AS P+ Sbjct: 180 GKAYWTVKNSWGPSWGEQGYIRVEKDSGASGGLCGIAMEASYPV 223 >4QRX-A nrPDB Length = 363 Score = 174 bits (440), Expect = 7e-44, Method: Compositional matrix adjust. Identities = 111/303 (36%), Positives = 170/303 (56%), Gaps = 20/303 (6%) Query: 20 LWHQWKRMYNKEYNGADDQ-HRRNIWEKNVKHIQEHNLRHDLGLVTYTLGLNQFTDMTFE 78 L+ W +NK Y D++ +R I++ N+K+I E N +++ +Y LGLN F DM+ + Sbjct: 65 LFESWMLKHNKIYKNIDEKIYRFEIFKDNLKYIDETNKKNN----SYWLGLNVFADMSND 120 Query: 79 EFKAKYLTEMS--RASDILSHGVPYEANNRAVPDKIDWRESGYVTEVKDQGNCGSCWAFS 136 EFK KY ++ + LS+ + +P+ +DWR+ G VT VK+QG+CGS WAFS Sbjct: 121 EFKEKYTGSIAGNYTTTELSYEEVLNDGDVNIPEYVDWRQKGAVTPVKNQGSCGSAWAFS 180 Query: 137 TTGTMEGQYMKNERTSISFSEQQLVDCSGPWGNNGCSGGLMENAYQYLKQFGLETESSYP 196 T+E +SEQ+L+DC + GC+GG +A Q + Q+G+ ++YP Sbjct: 181 AVSTIESIIKIRTGNLNEYSEQELLDCDRR--SYGCNGGYPWSALQLVAQYGIHYRNTYP 238 Query: 197 YTAVEGQCRYNKQLG--VAKVTGYYTVHSGSEVELKNLVGARRPAAVAVDVE-SDFMMYR 253 Y V+ CR +++ G AK G V +E L + A +P +V ++ DF +YR Sbjct: 239 YEGVQRYCR-SREKGPYAAKTDGVRQVQPYNEGALLYSI-ANQPVSVVLEAAGKDFQLYR 296 Query: 254 SGIYQSQTCSPLRVNHAVLAVGYGTQGGTDYWIVKNSWGTYWGERGYIRMARNRGNMCGI 313 GI+ + +V+HAV AVGY G +Y +++NSWGT WGE GYIR+ R GN G+ Sbjct: 297 GGIFVGPCGN--KVDHAVAAVGY----GPNYILIRNSWGTGWGENGYIRIKRGTGNSYGV 350 Query: 314 ASL 316 L Sbjct: 351 CGL 353 >4YYW-A nrPDB Length = 220 Score = 172 bits (437), Expect = 1e-43, Method: Compositional matrix adjust. Identities = 94/222 (42%), Positives = 136/222 (61%), Gaps = 9/222 (4%) Query: 108 VPDKIDWRESGYVTEVKDQGNCGSCWAFSTTGTMEGQYMKNERTSISFSEQQLVDCSGPW 167 +P+ +DWR G V ++DQG CGSCW FS T +EG T S SEQ+L+DC+ + Sbjct: 1 LPETVDWRSKGAVDPIRDQGKCGSCWVFSVTVVVEGIVKIVTDTLPSLSEQELLDCAPSY 60 Query: 168 GNNGCSGGLMENAYQY-LKQFGLETESSYPYTAVEGQCRYNKQLG-VAKVTGYYTVHSGS 225 + GC GG M+ AY Y +K G+ +ES YPYTA +G C K VA ++ Y V + + Sbjct: 61 KDLGCKGGWMDKAYDYIIKDRGITSESDYPYTARKGACDSRKATEVVATISSYEDVPADN 120 Query: 226 EVELKNLVGARRPAAVAVDVESDFMM-YRSGIYQSQTCSPLRVNHAVLAVGYGTQGGTDY 284 E LK V A +P +VA+D S + Y SG++ +C + +HAV+ VGYGT+ G +Y Sbjct: 121 EDALKKAV-ANQPVSVAIDASSAAVKEYSSGVFVG-SCG-VANDHAVVVVGYGTESGVNY 177 Query: 285 WIVKNSWGTYWGERGYIRMARNRGN---MCGIASLASLPMVA 323 W+V+NSWGT WGE GY+++ R+ + CGIA ++ P+ A Sbjct: 178 WLVRNSWGTKWGEEGYMKLERDTAHPAGKCGIAMESTYPVKA 219 >1O0E-A nrPDB Length = 208 Score = 172 bits (437), Expect = 2e-43, Method: Compositional matrix adjust. Identities = 103/219 (47%), Positives = 133/219 (60%), Gaps = 14/219 (6%) Query: 108 VPDKIDWRESGYVTEVKDQGNCGSCWAFSTTGTMEGQYMKNERTSISFSEQQLVDCSGPW 167 +P++IDWR+ G VT VK+QG+CGSCWAFST T+E IS SEQ+LVDC Sbjct: 1 LPEQIDWRKKGAVTPVKNQGSCGSCWAFSTVSTVESINQIRTGNLISLSEQELVDCDKK- 59 Query: 168 GNNGCSGGLMENAYQY-LKQFGLETESSYPYTAVEGQCRYNKQLGVAKVTGYYTVHSGSE 226 N+GC GG AYQY + G++T+++YPY AV+G C+ + V + GY V +E Sbjct: 60 -NHGCLGGAFVFAYQYIINNGGIDTQANYPYKAVQGPCQAASK--VVSIDGYNGVPFCNE 116 Query: 227 VELKNLVGARRPAAVAVDVES-DFMMYRSGIYQSQTCSPLRVNHAVLAVGYGTQGGTDYW 285 LK V A +P+ VA+D S F Y SGI+ S C ++NH V VGY +YW Sbjct: 117 XALKQAV-AVQPSTVAIDASSAQFQQYSSGIF-SGPCG-TKLNHGVTIVGY----QANYW 169 Query: 286 IVKNSWGTYWGERGYIRMARNRG-NMCGIASLASLPMVA 323 IV+NSWG YWGE+GYIRM R G +CGIA L P A Sbjct: 170 IVRNSWGRYWGEKGYIRMLRVGGCGLCGIARLPYYPTKA 208 >2ACT-A nrPDB Length = 220 Score = 171 bits (434), Expect = 3e-43, Method: Compositional matrix adjust. Identities = 93/219 (42%), Positives = 127/219 (57%), Gaps = 8/219 (3%) Query: 108 VPDKIDWRESGYVTEVKDQGNCGSCWAFSTTGTMEGQYMKNERTSISFSEQQLVDCSGPW 167 +P +DWR +G V ++K QG CG CWAFS T+EG + IS SEQ+L+DC Sbjct: 1 LPSYVDWRSAGAVVDIKSQGECGGCWAFSAIATVEGINKITSGSLISLSEQELIDCGRTQ 60 Query: 168 GNNGCSGGLMENAYQY-LKQFGLETESSYPYTAVEGQCRYNKQ-LGVAKVTGYYTVHSGS 225 GC GG + + +Q+ + G+ TE +YPYTA +G C Q + Y V + Sbjct: 61 NTRGCDGGYITDGFQFIINDGGINTEENYPYTAQDGDCDVALQDQKYVTIDTYENVPYNN 120 Query: 226 EVELKNLVGARRPAAVAVDVESD-FMMYRSGIYQSQTCSPLRVNHAVLAVGYGTQGGTDY 284 E L+ V +P +VA+D D F Y SGI+ + V+HA++ VGYGT+GG DY Sbjct: 121 EWALQTAV-TYQPVSVALDAAGDAFKQYASGIFTGPCGT--AVDHAIVIVGYGTEGGVDY 177 Query: 285 WIVKNSWGTYWGERGYIRMARNRG--NMCGIASLASLPM 321 WIVKNSW T WGE GY+R+ RN G CGIA++ S P+ Sbjct: 178 WIVKNSWDTTWGEEGYMRILRNVGGAGTCGIATMPSYPV 216 >1ICF-A nrPDB Length = 175 Score = 171 bits (433), Expect = 4e-43, Method: Compositional matrix adjust. Identities = 86/172 (50%), Positives = 107/172 (62%), Gaps = 3/172 (1%) Query: 108 VPDKIDWRESGYVTEVKDQGNCGSCWAFSTTGTMEGQYMKNERTSISFSEQQLVDCSGPW 167 P +DWRE GYVT VK+QG CGSCWAFS TG +EGQ + IS SEQ LVDCSGP Sbjct: 1 APRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQ 60 Query: 168 GNNGCSGGLMENAYQYLKQ-FGLETESSYPYTAVEGQCRYNKQLGVAKVTGYYTVHSGSE 226 GN GC+GGLM+ A+QY++ GL++E SYPY A E C+YN + VA TG+ + E Sbjct: 61 GNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPK-QE 119 Query: 227 VELKNLVGARRPAAVAVDV-ESDFMMYRSGIYQSQTCSPLRVNHAVLAVGYG 277 L V P +VA+D F+ Y+ GIY CS ++H VL VGYG Sbjct: 120 KALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYG 171 >1AEC-A nrPDB Length = 218 Score = 171 bits (432), Expect = 5e-43, Method: Compositional matrix adjust. Identities = 93/219 (42%), Positives = 128/219 (58%), Gaps = 8/219 (3%) Query: 108 VPDKIDWRESGYVTEVKDQGNCGSCWAFSTTGTMEGQYMKNERTSISFSEQQLVDCSGPW 167 +P +DWR +G V ++K QG CG CWAFS T+EG IS SEQ+L+DC Sbjct: 1 LPSYVDWRSAGAVVDIKSQGECGGCWAFSAIATVEGINKIVTGVLISLSEQELIDCGRTQ 60 Query: 168 GNNGCSGGLMENAYQYL-KQFGLETESSYPYTAVEGQCRYNKQ-LGVAKVTGYYTVHSGS 225 GC+GG + + +Q++ G+ TE +YPYTA +G+C + Q + Y V + Sbjct: 61 NTRGCNGGYITDGFQFIINNGGINTEENYPYTAQDGECNVDLQNEKYVTIDTYENVPYNN 120 Query: 226 EVELKNLVGARRPAAVAVDVESD-FMMYRSGIYQSQTCSPLRVNHAVLAVGYGTQGGTDY 284 E L+ V +P +VA+D D F Y SGI+ + ++HAV VGYGT+GG DY Sbjct: 121 EWALQTAV-TYQPVSVALDAAGDAFKQYSSGIFTGPCGT--AIDHAVTIVGYGTEGGIDY 177 Query: 285 WIVKNSWGTYWGERGYIRMARNRG--NMCGIASLASLPM 321 WIVKNSW T WGE GY+R+ RN G CGIA++ S P+ Sbjct: 178 WIVKNSWDTTWGEEGYMRILRNVGGAGTCGIATMPSYPV 216 >1IWD-A nrPDB Length = 215 Score = 168 bits (425), Expect = 3e-42, Method: Compositional matrix adjust. Identities = 95/221 (42%), Positives = 131/221 (59%), Gaps = 11/221 (4%) Query: 108 VPDKIDWRESGYVTEVKDQGNCGSCWAFSTTGTMEGQYMKNERTSISFSEQQLVDCSGPW 167 +P +DWR G V +K+Q CGSCWAFS +E IS SEQ+LVDC Sbjct: 1 LPSFVDWRSKGAVNSIKNQKQCGSCWAFSAVAAVESINKIRTGQLISLSEQELVDCDT-- 58 Query: 168 GNNGCSGGLMENAYQYL-KQFGLETESSYPYTAVEGQCRYNKQLGVAKVTGYYTVHSGSE 226 ++GC+GG M NA+QY+ G++T+ +YPY+AV+G C+ + L V + G+ V +E Sbjct: 59 ASHGCNGGWMNNAFQYIITNGGIDTQQNYPYSAVQGSCKPYR-LRVVSINGFQRVTRNNE 117 Query: 227 VELKNLVGARRPAAVAVDVE-SDFMMYRSGIYQSQTCSPLRVNHAVLAVGYGTQGGTDYW 285 L++ V A +P +V V+ + F Y SGI+ + C + NH V+ VGYGTQ G +YW Sbjct: 118 SALQSAV-ASQPVSVTVEAAGAPFQHYSSGIF-TGPCGTAQ-NHGVVIVGYGTQSGKNYW 174 Query: 286 IVKNSWGTYWGERGYIRMARN---RGNMCGIASLASLPMVA 323 IV+NSWG WG +GYI M RN +CGIA L S P A Sbjct: 175 IVRNSWGQNWGNQGYIWMERNVASSAGLCGIAQLPSYPTKA 215 >6MIS-A nrPDB Length = 215 Score = 162 bits (410), Expect = 2e-40, Method: Compositional matrix adjust. Identities = 85/216 (39%), Positives = 126/216 (58%), Gaps = 8/216 (3%) Query: 108 VPDKIDWRESGYVTEVKDQGNCGSCWAFSTTGTMEGQYMKNERTSISFSEQQLVDCSGPW 167 VP IDWR+SG VT VK+QG CGSCWAF++ T+E Y +S SEQQ++DC+ + Sbjct: 1 VPQSIDWRDSGAVTSVKNQGRCGSCWAFASIATVESIYKIKRGNLVSLSEQQVLDCAVSY 60 Query: 168 GNNGCSGGLMENAYQY-LKQFGLETESSYPYTAVEGQCRYNKQLGVAKVTGYYTVHSGSE 226 GC GG + AY + + G+ + + YPY A +G C+ N A +T Y V +E Sbjct: 61 ---GCKGGWINKAYSFIISNKGVASAAIYPYKAAKGTCKTNGVPNSAYITRYTYVQRNNE 117 Query: 227 VELKNLVGARRPAAVAVDVESDFMMYRSGIYQSQTCSPLRVNHAVLAVGYGT-QGGTDYW 285 + V + +P A A+D +F Y+ G++ + R+NHA++ +GYG G +W Sbjct: 118 RNMMYAV-SNQPIAAALDASGNFQHYKRGVFTGPCGT--RLNHAIVIIGYGQDSSGKKFW 174 Query: 286 IVKNSWGTYWGERGYIRMARNRGNMCGIASLASLPM 321 IV+NSWG WGE GYIR+AR+ + G+ +A P+ Sbjct: 175 IVRNSWGAGWGEGGYIRLARDVSSSFGLCGIAMDPL 210 >2B1M-A nrPDB Length = 246 Score = 158 bits (399), Expect = 4e-39, Method: Compositional matrix adjust. Identities = 89/228 (39%), Positives = 130/228 (57%), Gaps = 16/228 (7%) Query: 109 PDKIDWRESGYVTEVKDQGNCGSCWAFSTTGTMEGQYMKNERTSISFSEQQLVDCSGPWG 168 P+ DW + G +T+VK QG CGS WAFS TG +E + +S SEQ+L+DC Sbjct: 3 PESWDWSKKGVITKVKFQGQCGSGWAFSATGAIEAAHAIATGNLVSLSEQELIDCVDE-- 60 Query: 169 NNGCSGGLMENAYQYL-KQFGLETESSYPYTAVEGQCRYNKQLGVAKVTGY-------YT 220 + GC G +++++ K G+ +E+ YPY A +G+C+ N+ + Y + Sbjct: 61 SEGCYNGWHYQSFEWVVKHGGIASEADYPYKARDGKCKANEIQDKVTIDNYGVQILSNES 120 Query: 221 VHSGSEVELKNLVGARRPAAVAVDVESDFMMYRSGIYQSQTCS-PLRVNHAVLAVGYGTQ 279 S +E L++ V +P +V++D + DF Y GIY CS P +NH VL VGYG++ Sbjct: 121 TESEAESSLQSFV-LEQPISVSIDAK-DFHFYSGGIYDGGNCSSPYGINHFVLIVGYGSE 178 Query: 280 GGTDYWIVKNSWGTYWGERGYIRMARNRGNM---CGIASLASLPMVAR 324 G DYWI KNSWG WG GYIR+ RN GN+ CG+ AS P++ + Sbjct: 179 DGVDYWIAKNSWGEDWGIDGYIRIQRNTGNLLGVCGMNYFASYPIIEK 226 >5A24-A nrPDB Length = 222 Score = 158 bits (399), Expect = 4e-39, Method: Compositional matrix adjust. Identities = 99/225 (44%), Positives = 127/225 (56%), Gaps = 13/225 (5%) Query: 108 VPDKIDWRESGYVTEVKDQGNCGSCWAFSTTGTMEGQYMKNERTSISFSEQQLVDCSGPW 167 VP +DWR +G VT VK+Q CG CWAFS +EG T S SE+Q+VDC Sbjct: 1 VPAAVDWRTAGAVTPVKNQQQCGCCWAFSAVAAIEGATQIKTGTLTSLSEEQIVDCDTNG 60 Query: 168 GNNGCSGGLMENAYQY-LKQFGLETESSYPYTA---VEGQCRYNKQLGVAKVTGYYTVHS 223 + GC+GG + A+QY + G++TES YPYTA G C + A +TGY V + Sbjct: 61 NDKGCNGGTPDGAFQYVVNNQGIDTESDYPYTAGGGSPGTCSASSYQPAASITGYQDVPA 120 Query: 224 GSEVELKNLVGARRPAAVAVDV-ESDFMMYRSGIYQSQTCSPLRVNHAVLAVGYGTQ--G 280 +E L+ A +P +VA+D + F Y SGIY S C+ ++HAV VGYGT Sbjct: 121 NNEQALQQAA-ATQPISVAIDASDPSFQSYSSGIY-SGPCN-TNLDHAVTVVGYGTDPNS 177 Query: 281 GTDYWIVKNSWGTYWGERGYI--RMARNRG-NMCGIASLASLPMV 322 G YWIVKNSWGT WG+ GYI +M N +CGIA AS P Sbjct: 178 GNSYWIVKNSWGTSWGQEGYIWMQMGLNAPYGVCGIAMQASYPTA 222 >1YAL-A nrPDB Length = 218 Score = 158 bits (399), Expect = 4e-39, Method: Compositional matrix adjust. Identities = 90/218 (41%), Positives = 121/218 (55%), Gaps = 10/218 (4%) Query: 109 PDKIDWRESGYVTEVKDQGNCGSCWAFSTTGTMEGQYMKNERTSISFSEQQLVDCSGPWG 168 P IDWR G VT VK+QG CGSCWAFST T+EG + SEQ+LVDC Sbjct: 2 PQSIDWRAKGAVTPVKNQGACGSCWAFSTIATVEGINKIVTGNLLELSEQELVDCDK--H 59 Query: 169 NNGCSGGLMENAYQYLKQFGLETESSYPYTAVEGQCRYNKQLGV-AKVTGYYTVHSGSEV 227 + GC GG + QY+ G+ T YPY A + +CR + G K+TGY V S E Sbjct: 60 SYGCKGGYQTTSLQYVANNGVHTSKVYPYQAKQYKCRATDKPGPKVKITGYKRVPSNCET 119 Query: 228 ELKNLVGARRPAAVAVDVE-SDFMMYRSGIYQSQTCSPLRVNHAVLAVGYGTQGGTDYWI 286 + A +P +V V+ F +Y+SG++ + +++HAV AVGYGT G +Y I Sbjct: 120 SFLGAL-ANQPLSVLVEAGGKPFQLYKSGVFDGPCGT--KLDHAVTAVGYGTSDGKNYII 176 Query: 287 VKNSWGTYWGERGYIRMARNRGN---MCGIASLASLPM 321 +KNSWG WGE+GY+R+ R GN CG+ + P Sbjct: 177 IKNSWGPNWGEKGYMRLKRQSGNSQGTCGVYKSSYYPF 214 >3U8E-A nrPDB Length = 222 Score = 157 bits (396), Expect = 7e-39, Method: Compositional matrix adjust. Identities = 93/221 (42%), Positives = 125/221 (56%), Gaps = 14/221 (6%) Query: 109 PDKIDWRESGYVTEVKDQGNCGSCWAFSTTGTMEGQYMKNERTSISFSEQQLVDCSGPWG 168 P IDWR+ G VT VKDQG CG CWAF TG +EG IS SEQQ+VDC Sbjct: 2 PASIDWRKKGAVTSVKDQGACGMCWAFGATGAIEGIDAITTGRLISVSEQQIVDCDT--X 59 Query: 169 NNGCSGGLMENAYQY-LKQFGLETESSYPYTAVEGQCRYNKQLGVAKVTGYYTVHSGSEV 227 GG ++A+++ + G+ ++++YPYT V+G C NK + A++ GY V + S Sbjct: 60 XXXXXGGDADDAFRWVITNGGIASDANYPYTGVDGTCDLNKPI-AARIDGYTNVPNSSSA 118 Query: 228 ELKNLVGARRPAAVAVDVES-DFMMYR-SGIYQSQTCS--PLRVNHAVLAVGYGTQG-GT 282 L + A++P +V + S F +Y GI+ +CS P V+H VL VGYG+ G Sbjct: 119 LLDAV--AKQPVSVNIYTSSTSFQLYTGPGIFAGSSCSDDPATVDHTVLIVGYGSNGTNA 176 Query: 283 DYWIVKNSWGTYWGERGYIRMARNRG---NMCGIASLASLP 320 DYWIVKNSWGT WG GYI + RN +C I + S P Sbjct: 177 DYWIVKNSWGTEWGIDGYILIRRNTNRPDGVCAIDAWGSYP 217 >4YYQ-A nrPDB Length = 217 Score = 155 bits (393), Expect = 2e-38, Method: Compositional matrix adjust. Identities = 89/219 (40%), Positives = 135/219 (61%), Gaps = 9/219 (4%) Query: 108 VPDKIDWRESGYVTEVKDQGNCGSCWAFSTTGTMEGQYMKNERTSISFSEQQLVDCSGPW 167 +P+ +DWR G V +++QG CGSCWAFS +E +S SEQQL+DC+ + Sbjct: 1 LPETVDWRSKGAVNPIRNQGQCGSCWAFSAVAAVESINKIVTGQLLSLSEQQLLDCAQSY 60 Query: 168 GNNGCSGGLMENAYQYLKQ-FGLETESSYPYTAVEGQCRYNKQLGVAKVTGYYTVHSGSE 226 N GC GG + A++Y+ Q G+ ++S+YPYT +GQCR +A + Y V S +E Sbjct: 61 KNLGCQGGWVNKAFEYIIQNRGITSQSNYPYTGHKGQCR-TGLASIATIDSYQYVPSNNE 119 Query: 227 VELKNLVGARRPAAVAVDVES-DFMMYRSGIYQSQTCSPLRVNHAVLAVGYGTQGGTDYW 285 LKN V A +P +VAV+ F +Y+SG++ + +C + ++HAV+ +GYG G DYW Sbjct: 120 NALKNAV-ANQPVSVAVEAAGRAFQLYKSGVF-TGSCG-VAIDHAVVLIGYGKYNGVDYW 176 Query: 286 IVKNSWGTYWGERGYIRMARN---RGNMCGIASLASLPM 321 +++NSWGT WGE+GY+++ RN CG+A L P+ Sbjct: 177 LLRNSWGTNWGEQGYMKLQRNVAQSAGKCGVARLCLYPV 215 >4PI3-A nrPDB Length = 216 Score = 154 bits (390), Expect = 4e-38, Method: Compositional matrix adjust. Identities = 91/220 (41%), Positives = 120/220 (54%), Gaps = 13/220 (5%) Query: 109 PDKIDWRESGYVTEVKDQGNCGSCWAFSTTGTMEGQYMKNERTSISFSEQQLVDCSGPWG 168 P +DWR G VT VKDQG CGSCWAFS G +E Q+ + SEQ LV C Sbjct: 3 PAAVDWRARGAVTAVKDQGQCGSCWAFSAIGNVECQWFLAGHPLTNLSEQMLVSCDKT-- 60 Query: 169 NNGCSGGLMENAYQYLKQ---FGLETESSYPYTAVEG---QCRYNKQLGVAKVTGYYTVH 222 ++GCSGGLM NA++++ Q + TE SYPY + EG C + A +TG+ + Sbjct: 61 DSGCSGGLMNNAFEWIVQENNGAVYTEDSYPYASGEGISPPCTTSGHTVGATITGHVELP 120 Query: 223 SGSEVELKNLVGARRPAAVAVDVESDFMMYRSGIYQSQTCSPLRVNHAVLAVGYGTQGGT 282 E ++ + P AVAVD S +M Y G+ S C +++H VL VGY Sbjct: 121 Q-DEAQIAAWLAVNGPVAVAVDA-SSWMTYTGGVMTS--CVSEQLDHGVLLVGYNDSAAV 176 Query: 283 DYWIVKNSWGTYWGERGYIRMARNRGNMCGIASLASLPMV 322 YWI+KNSW T WGE GYIR+A+ N C + AS +V Sbjct: 177 PYWIIKNSWTTQWGEEGYIRIAKGS-NQCLVKEEASSAVV 215 >6EXO-A nrPDB Length = 215 Score = 153 bits (386), Expect = 1e-37, Method: Compositional matrix adjust. Identities = 89/209 (42%), Positives = 115/209 (55%), Gaps = 13/209 (6%) Query: 109 PDKIDWRESGYVTEVKDQGNCGSCWAFSTTGTMEGQYMKNERTSISFSEQQLVDCSGPWG 168 P +DWRE G VT VKDQG CGSCWAFST G +EGQ+ +S SEQ LV C Sbjct: 2 PAAVDWREKGAVTPVKDQGQCGSCWAFSTIGNIEGQWQVAGNPLVSLSEQMLVSCDTI-- 59 Query: 169 NNGCSGGLMENAYQYLKQF---GLETESSYPYTAVEG---QCRYNKQLGVAKVTGYYTVH 222 + GC GGLM+NA+ ++ + TE+SYPY + G QC+ N A +T + + Sbjct: 60 DFGCGGGLMDNAFNWIVNSNGGNVFTEASYPYVSGNGEQPQCQMNGHEIGAAITDHVDLP 119 Query: 223 SGSEVELKNLVGARRPAAVAVDVESDFMMYRSGIYQSQTCSPLRVNHAVLAVGYGTQGGT 282 E + + P A+AVD S FM Y GI S C+ +++H VL VGY Sbjct: 120 Q-DEDAIAAYLAENGPLAIAVDATS-FMDYNGGILTS--CTSEQLDHGVLLVGYNDASNP 175 Query: 283 DYWIVKNSWGTYWGERGYIRMARNRGNMC 311 YWI+KNSW WGE GYIR+ + N C Sbjct: 176 PYWIIKNSWSNMWGEDGYIRIEKGT-NQC 203 >2BDZ-A nrPDB Length = 214 Score = 152 bits (384), Expect = 2e-37, Method: Compositional matrix adjust. Identities = 89/218 (40%), Positives = 120/218 (55%), Gaps = 14/218 (6%) Query: 109 PDKIDWRESGYVTEVKDQGNCGSCWAFSTTGTMEGQYMKNERTSISFSEQQLVDCSGPWG 168 P+ IDWRE G VT VK+Q CGSCWAFST T+EG IS SEQ+L+DC Sbjct: 2 PESIDWREKGAVTPVKNQNPCGSCWAFSTVATIEGINKIITGQLISLSEQELLDCE--RR 59 Query: 169 NNGCSGGLMENAYQYLKQFGLETESSYPYTAVEGQCRYNKQLGV-AKVTGYYTVHSGSEV 227 ++GC GG + QY+ G+ TE YPY +G+CR + G +TGY V + E+ Sbjct: 60 SHGCDGGYQTTSLQYVVDNGVHTEREYPYEKKQGRCRAKDKKGPKVYITGYKYVPANDEI 119 Query: 228 ELKNLVGARRPAAVAVDVES-DFMMYRSGIYQSQTCSPLRVNHAVLAVGYGTQGGTDYWI 286 L + A +P +V D F Y+ GIY+ + +HAV AVGYG Y + Sbjct: 120 SLIQAI-ANQPVSVVTDSRGRGFQFYKGGIYEGPCGT--NTDHAVTAVGYGKT----YLL 172 Query: 287 VKNSWGTYWGERGYIRMARNRG---NMCGIASLASLPM 321 +KNSWG WGE+GYIR+ R G CG+ + + P+ Sbjct: 173 LKNSWGPNWGEKGYIRIKRASGRSKGTCGVYTSSFFPI 210 >1PPO-A nrPDB Length = 216 Score = 151 bits (382), Expect = 4e-37, Method: Compositional matrix adjust. Identities = 90/212 (42%), Positives = 128/212 (60%), Gaps = 9/212 (4%) Query: 108 VPDKIDWRESGYVTEVKDQGNCGSCWAFSTTGTMEGQYMKNERTSISFSEQQLVDCSGPW 167 +P+ +DWR+ G VT V+ QG+CGSCWAFS T+EG + SEQ+LVDC Sbjct: 1 LPENVDWRKKGAVTPVRHQGSCGSCWAFSAVATVEGINKIRTGKLVELSEQELVDCE--R 58 Query: 168 GNNGCSGGLMENAYQYLKQFGLETESSYPYTAVEGQCRYNKQLG--VAKVTGYYTVHSGS 225 ++GC GG A +Y+ + G+ S YPY A +G CR KQ+G + K +G V + Sbjct: 59 RSHGCKGGYPPYALEYVAKNGIHLRSKYPYKAKQGTCR-AKQVGGPIVKTSGVGRVQPNN 117 Query: 226 EVELKNLVGARRPAAVAVDVES-DFMMYRSGIYQSQTCSPLRVNHAVLAVGYGTQGGTDY 284 E L N + A++P +V V+ + F +Y+ GI++ + +V+HAV AVGYG GG Y Sbjct: 118 EGNLLNAI-AKQPVSVVVESKGRPFQLYKGGIFEGPCGT--KVDHAVTAVGYGKSGGKGY 174 Query: 285 WIVKNSWGTYWGERGYIRMARNRGNMCGIASL 316 ++KNSWGT WGE+GYIR+ R GN G+ L Sbjct: 175 ILIKNSWGTAWGEKGYIRIKRAPGNSPGVCGL 206 >1M6D-A nrPDB Length = 214 Score = 150 bits (378), Expect = 1e-36, Method: Compositional matrix adjust. Identities = 95/219 (43%), Positives = 128/219 (58%), Gaps = 10/219 (4%) Query: 108 VPDKIDWRESGYVTEVKDQGNCGSCWAFSTTGTMEGQYMKNERTSISFSEQQLVDCSGPW 167 P + DWR G VT+VKDQG CGSCWAFS TG +EGQ+ N+ T +S SEQ+L+DC Sbjct: 1 APPEWDWRSKGAVTKVKDQGMCGSCWAFSVTGNVEGQWFLNQGTLLSLSEQELLDCDKM- 59 Query: 168 GNNGCSGGLMENAYQYLKQF-GLETESSYPYTAVEGQCRYNKQLGVAKVTGYYTVH-SGS 225 + C GGL NAY +K GLETE Y Y C+++ + AKV +V S + Sbjct: 60 -DKACMGGLPSNAYSAIKNLGGLETEDDYSYQGHMQSCQFSAE--KAKVYIQDSVELSQN 116 Query: 226 EVELKNLVGARRPAAVAVDVESDFMMYRSGIYQS--QTCSPLRVNHAVLAVGYGTQGGTD 283 E +L + R P +VA++ YR GI + CSP ++HAVL VGYG + Sbjct: 117 EQKLAAWLAKRGPISVAINAFG-MQFYRHGISRPLRPLCSPWLIDHAVLLVGYGQRSDVP 175 Query: 284 YWIVKNSWGTYWGERGYIRMARNRGNMCGIASLASLPMV 322 +W +KNSWGT WGE+GY + R G CG+ ++AS +V Sbjct: 176 FWAIKNSWGTDWGEKGYYYLHRGSG-ACGVNTMASSAVV 213 >3BPF-A nrPDB Length = 241 Score = 144 bits (364), Expect = 4e-35, Method: Compositional matrix adjust. Identities = 83/225 (36%), Positives = 124/225 (55%), Gaps = 22/225 (9%) Query: 113 DWRESGYVTEVKDQGNCGSCWAFSTTGTMEGQYMKNERTSISFSEQQLVDCSGPWGNNGC 172 DWR VT VKDQ NCGSCWAFS+ G++E QY + I+ SEQ+LVDCS + N GC Sbjct: 23 DWRLHSGVTPVKDQKNCGSCWAFSSIGSVESQYAIRKNKLITLSEQELVDCS--FKNYGC 80 Query: 173 SGGLMENAYQYLKQF-GLETESSYPYTA-VEGQCRYNKQLGVAKVTGYYTVHSGSEVELK 230 +GGL+ NA++ + + G+ + YPY + C ++ + Y +V E Sbjct: 81 NGGLINNAFEDMIELGGICPDGDYPYVSDAPNLCNIDRCTEKYGIKNYLSVPDNKLKEAL 140 Query: 231 NLVGARRPAAVAVDVESDFMMYRSGIYQSQTCSPLRVNHAVLAVGYG--------TQGGT 282 +G P +++V V DF Y+ GI+ + L NHAV+ VG+G T+ G Sbjct: 141 RFLG---PISISVAVSDDFAFYKEGIFDGECGDQL--NHAVMLVGFGMKEIVNPLTKKGE 195 Query: 283 D--YWIVKNSWGTYWGERGYIRMARNRGNM---CGIASLASLPMV 322 Y+I+KNSWG WGERG+I + + + CG+ + A +P++ Sbjct: 196 KHYYYIIKNSWGQQWGERGFINIETDESGLMRKCGLGTDAFIPLI 240 >2CIO-A nrPDB Length = 212 Score = 143 bits (360), Expect = 1e-34, Method: Compositional matrix adjust. Identities = 86/212 (40%), Positives = 124/212 (58%), Gaps = 13/212 (6%) Query: 108 VPDKIDWRESGYVTEVKDQGNCGSCWAFSTTGTMEGQYMKNERTSISFSEQQLVDCSGPW 167 +P+ +DWR+ G VT VK+QG+CGSCWAFS T+EG +SEQ+L+DC Sbjct: 1 IPEYVDWRQKGAVTPVKNQGSCGSCWAFSAVVTIEGIIKIRTGNLNQYSEQELLDCDRR- 59 Query: 168 GNNGCSGGLMENAYQYLKQFGLETESSYPYTAVEGQCRYNKQLG--VAKVTGYYTVHSGS 225 + GC+GG +A Q + Q+G+ ++YPY V+ CR +++ G AK G V + Sbjct: 60 -SYGCNGGYPWSALQLVAQYGIHYRNTYPYEGVQRYCR-SREKGPYAAKTDGVRQVQPYN 117 Query: 226 EVELKNLVGARRPAAVAVDVE-SDFMMYRSGIYQSQTCSPLRVNHAVLAVGYGTQGGTDY 284 E L + A +P +V ++ DF +YR GI+ + +V+HAV AVGY G +Y Sbjct: 118 EGALLYSI-ANQPVSVVLEAAGKDFQLYRGGIFVGPCGN--KVDHAVAAVGY----GPNY 170 Query: 285 WIVKNSWGTYWGERGYIRMARNRGNMCGIASL 316 ++KNSWGT WGE GYIR+ R GN G+ L Sbjct: 171 ILIKNSWGTGWGENGYIRIKRGTGNSYGVCGL 202 >1GEC-E nrPDB Length = 216 Score = 139 bits (349), Expect = 2e-33, Method: Compositional matrix adjust. Identities = 93/220 (42%), Positives = 125/220 (56%), Gaps = 12/220 (5%) Query: 108 VPDKIDWRESGYVTEVKDQGNCGSCWAFSTTGTMEGQYMKNERTSISFSEQQLVDCSGPW 167 +P+ +DWR G VT VK QG C SCWAFST T+EG + SEQ+LVDC Sbjct: 1 LPESVDWRAKGAVTPVKHQGYCESCWAFSTVATVEGINKIKTGNLVELSEQELVDCD--L 58 Query: 168 GNNGCSGGLMENAYQYLKQFGLETESSYPYTAVEGQCRYNKQLGVAKV--TGYYTVHSGS 225 + GC+ G + QY+ Q G+ + YPY A + CR N Q+G KV G V S + Sbjct: 59 QSYGCNRGYQSTSLQYVAQNGIHLRAKYPYIAKQQTCRAN-QVGGPKVKTNGVGRVQSNN 117 Query: 226 EVELKNLVGARRPAAVAVDVES-DFMMYRSGIYQSQTCSPLRVNHAVLAVGYGTQGGTDY 284 E L N + A +P +V V+ DF Y+ GI++ +C +V+HAV AVGYG GG Y Sbjct: 118 EGSLLNAI-AHQPVSVVVESAGRDFQNYKGGIFEG-SCG-TKVDHAVTAVGYGKSGGKGY 174 Query: 285 WIVKNSWGTYWGERGYIRMARNRGN---MCGIASLASLPM 321 ++KNSWG WGE GYIR+ R GN +CG+ + P+ Sbjct: 175 ILIKNSWGPGWGENGYIRIRRASGNSPGVCGVYRSSYYPI 214 >3BPM-A nrPDB Length = 243 Score = 133 bits (335), Expect = 9e-32, Method: Compositional matrix adjust. Identities = 82/228 (35%), Positives = 117/228 (51%), Gaps = 28/228 (12%) Query: 113 DWRESGYVTEVKDQGNCGSCWAFSTTGTMEGQYMKNERTSISFSEQQLVDCSGPWGNNGC 172 DWR G VT VKDQ CGSCWAFS+ G++E QY ++ FSEQ+LVDCS NNGC Sbjct: 25 DWRLHGGVTPVKDQALCGSCWAFSSVGSVESQYAIRKKALFLFSEQELVDCSVK--NNGC 82 Query: 173 SGGLMENAYQYLKQF-GLETESSYPYTAVEGQCRYNKQLGVAKVTGYYTVHSGSEVELKN 231 GG + NA+ + GL ++ YPY + + + + YT+ S + Sbjct: 83 YGGYITNAFDDMIDLGGLCSQDDYPYVS-----NLPETCNLKRCNERYTIKSYVSIPDDK 137 Query: 232 LVGARR---PAAVAVDVESDFMMYRSGIYQSQT-CSPLRVNHAVLAVGYGTQGGTD---- 283 A R P ++++ DF YR G Y + +P NHAV+ VGYG + + Sbjct: 138 FKEALRYLGPISISIAASDDFAFYRGGFYDGECGAAP---NHAVILVGYGMKDIYNEDTG 194 Query: 284 ------YWIVKNSWGTYWGERGYIRMARNRG---NMCGIASLASLPMV 322 Y+I+KNSWG+ WGE GYI + + C I + A +P++ Sbjct: 195 RMEKFYYYIIKNSWGSDWGEGGYINLETDENGYKKTCSIGTEAYVPLL 242 >3PDF-A nrPDB Length = 441 Score = 130 bits (328), Expect = 6e-31, Method: Compositional matrix adjust. Identities = 100/308 (32%), Positives = 149/308 (48%), Gaps = 37/308 (12%) Query: 39 HRRNIWEK--NVKHIQEHNLRHDLGLVTYTLGLNQFTDMTFEEFKAKYLTEMSRASDILS 96 H +N EK N + +HN + + +T T+ E++ L +M R S S Sbjct: 131 HLKNSQEKYSNRLYKYDHNFVKAINAIQ-----KSWTATTYMEYETLTLGDMIRRSGGHS 185 Query: 97 HGVP----------YEANNRAVPDKIDWRES---GYVTEVKDQGNCGSCWAFSTTGTMEG 143 +P + +P DWR +V+ V++Q +CGSC++F++ G +E Sbjct: 186 RKIPRPKPAPLTAEIQQKILFLPTSWDWRNVHGINFVSPVRNQASCGSCYSFASMGMLEA 245 Query: 144 QY--MKNERTSISFSEQQLVDCSGPWGNNGCSGGL-MENAYQYLKQFGLETESSYPYTAV 200 + + N + S Q++V CS GC GG A +Y + FGL E+ +PYT Sbjct: 246 RIRILTNNSQTPILSPQEVVSCSQ--YAQGCEGGFPYLIAGKYAQDFGLVEEACFPYTGT 303 Query: 201 EGQCRYNKQLGVAKVTGYYTV---HSG-SEVELKNLVGARRPAAVAVDVESDFMMYRSGI 256 + C+ + + Y+ V + G +E +K + P AVA +V DF+ Y+ GI Sbjct: 304 DSPCKMKEDCFRYYSSEYHYVGGFYGGCNEALMKLELVHHGPMAVAFEVYDDFLHYKKGI 363 Query: 257 YQS----QTCSPLRV-NHAVLAVGYGTQG--GTDYWIVKNSWGTYWGERGYIRMARNRGN 309 Y +P + NHAVL VGYGT G DYWIVKNSWGT WGE GY R+ R + Sbjct: 364 YHHTGLRDPFNPFELTNHAVLLVGYGTDSASGMDYWIVKNSWGTGWGENGYFRIRRGT-D 422 Query: 310 MCGIASLA 317 C I S+A Sbjct: 423 ECAIESIA 430 >1JQP-A nrPDB Length = 438 Score = 129 bits (325), Expect = 1e-30, Method: Compositional matrix adjust. Identities = 82/228 (35%), Positives = 120/228 (52%), Gaps = 20/228 (8%) Query: 107 AVPDKIDWRES---GYVTEVKDQGNCGSCWAFSTTGTMEGQY--MKNERTSISFSEQQLV 161 ++P+ DWR +V+ V++Q +CGSC++F++ G +E + + N + S Q++V Sbjct: 205 SLPESWDWRNVRGINFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEVV 264 Query: 162 DCSGPWGNNGCSGGL-MENAYQYLKQFGLETESSYPYTAVEGQCRYNKQL----GVAKVT 216 CS P+ GC GG A +Y + FG+ E+ +PYTA + C+ + Sbjct: 265 SCS-PYAQ-GCDGGFPYLIAGKYAQDFGVVEENCFPYTATDAPCKPKENCLRYYSSEYYY 322 Query: 217 GYYTVHSGSEVELKNLVGARRPAAVAVDVESDFMMYRSGIYQ----SQTCSPLRV-NHAV 271 +E +K + P AVA +V DF+ Y SGIY S +P + NHAV Sbjct: 323 VGGFYGGCNEALMKLELVKHGPMAVAFEVHDDFLHYHSGIYHHTGLSDPFNPFELTNHAV 382 Query: 272 LAVGYGTQG--GTDYWIVKNSWGTYWGERGYIRMARNRGNMCGIASLA 317 L VGYG G DYWIVKNSWG+ WGE GY R+ R + C I S+A Sbjct: 383 LLVGYGKDPVTGLDYWIVKNSWGSQWGESGYFRIRRGT-DECAIESIA 429 >3IOQ-A nrPDB Length = 213 Score = 129 bits (323), Expect = 2e-30, Method: Compositional matrix adjust. Identities = 88/222 (39%), Positives = 119/222 (53%), Gaps = 14/222 (6%) Query: 108 VPDKIDWRESGYVTEVKDQGNCGSCWAFSTTGTMEGQYMKNERTSISFSEQQLVDCSGPW 167 +P IDWR+ G VT V++QG CGSCW FS+ +EG +S SEQ+L+DC Sbjct: 1 IPTSIDWRQKGAVTPVRNQGGCGSCWTFSSVAAVEGINKIVTGQLLSLSEQELLDCE--R 58 Query: 168 GNNGCSGGLMENAYQYLKQFGLETESSYPYTAVEGQCRYNKQLGV-AKVTGYYTVHSGSE 226 + GC GG A QY+ G+ YPY V+ QCR ++ G K G V +E Sbjct: 59 RSYGCRGGFPLYALQYVANSGIHLRQYYPYEGVQRQCRASQAKGPKVKTDGVGRVPRNNE 118 Query: 227 VELKNLVGARRPAAVAVDVES-DFMMYRSGIYQSQTCSPLRVNHAVLAVGYGTQGGTDYW 285 L + A +P ++ V+ + F YR GI+ + C ++HAV AVGY G DY Sbjct: 119 QALIQRI-AIQPVSIVVEAKGRAFQNYRGGIF-AGPCG-TSIDHAVAAVGY----GNDYI 171 Query: 286 IVKNSWGTYWGERGYIRMARNRGN---MCGIASLASLPMVAR 324 ++KNSWGT WGE GYIR+ R GN CG+ S + P R Sbjct: 172 LIKNSWGTGWGEGGYIRIKRGSGNPQGACGVLSDSVFPTKNR 213 >5I4H-A nrPDB Length = 106 Score = 127 bits (320), Expect = 6e-30, Method: Compositional matrix adjust. Identities = 60/103 (58%), Positives = 73/103 (70%), Gaps = 1/103 (0%) Query: 108 VPDKIDWRESGYVTEVKDQGNCGSCWAFSTTGTMEGQYMKNERTSISFSEQQLVDCSGPW 167 P +DWRE GYVT VK+QG CGS WAFS TG +EGQ + IS SEQ LVDCSGP Sbjct: 2 APRSVDWREKGYVTPVKNQGQCGSSWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQ 61 Query: 168 GNNGCSGGLMENAYQYLKQ-FGLETESSYPYTAVEGQCRYNKQ 209 GN GC+GGLM+ A+QY++ GL++E SYPY A E C+YN + Sbjct: 62 GNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPK 104 >5JT8-A nrPDB Length = 333 Score = 126 bits (316), Expect = 1e-29, Method: Compositional matrix adjust. Identities = 87/315 (27%), Positives = 158/315 (50%), Gaps = 38/315 (12%) Query: 1 MRLFILAVLTVGV-LGSND------DLWHQWKRMYNKEYNGADDQHRR-NIWEKNVKHIQ 52 M+ ++A L V +GS + Q+K+++ K Y A+++ RR + +++ +K ++ Sbjct: 1 MKFLLVAALCALVAIGSCKPTREEIKTFEQFKKVFGKVYRNAEEEARREHHFKEQLKWVE 60 Query: 53 EHNLRHDLGLVTYTLGLNQFTDMTFEEFKAK---------YLT-EMSRASDILSHGVPYE 102 EHN G+ +N+++DM+ +EF Y+ E ++ I ++G Sbjct: 61 EHN-----GIDGVEYAINEYSDMSEQEFSFHLSGGGLNFTYMKMEAAKEPLINTYG---- 111 Query: 103 ANNRAVPDKIDWRESGYVTEVKDQGNCGSCWAFSTTGTMEGQYMKNERTSISFSEQQLVD 162 ++P DWR+ +T ++ QG+CGSCWAF+ G E Y ++ SI SEQ+LVD Sbjct: 112 ----SLPQNFDWRQKARLTRIRQQGSCGSCWAFAAAGVAESLYSIQKQQSIELSEQELVD 167 Query: 163 CS-----GPWGNNGCSGGLMENAYQYLKQFGLETESSYPYTAVEGQCRYNKQLGVAKVTG 217 C+ + NGC G A++Y+ + GL E +YPY C + + V+G Sbjct: 168 CTYNRYDPSYQCNGCGSGYSTEAFKYMIRTGLVEERNYPYNMRTQWCDPDVEGQRYHVSG 227 Query: 218 YYTV-HSGSEVELKNLVGARRPAAVAVDVESD-FMMYRSGIYQSQTCSPLRVNHAVLAVG 275 Y + + S+ ++ + P + + ++ F +G+ + + +HAV+ VG Sbjct: 228 YQQLRYHSSDEDVMYTIQQHGPVVIYMHGSNNYFRNLGNGVLRGVAYNDAYTDHAVILVG 287 Query: 276 YGTQGGTDYWIVKNS 290 +GT G DYWI++NS Sbjct: 288 WGTVQGVDYWIIRNS 302 >1XKG-A nrPDB Length = 312 Score = 123 bits (308), Expect = 1e-28, Method: Compositional matrix adjust. Identities = 90/298 (30%), Positives = 140/298 (46%), Gaps = 30/298 (10%) Query: 21 WHQWKRMYNKEYNGADDQH--RRNIWEKNVKHIQEHNLRHDLGLVTYTLGLNQFTDMTFE 78 + ++K+ +NK Y +D+ R+N E +VK++Q + +N +D++ + Sbjct: 8 FEEYKKAFNKSYATFEDEEAARKNFLE-SVKYVQSNGG-----------AINHLSDLSLD 55 Query: 79 EFKAKYLTEMSRASDILSHGVPYEANNRA------VPDKIDWRESGYVTEVKDQGNCGSC 132 EFK ++L + A + L A A P +ID R+ VT ++ QG CGS Sbjct: 56 EFKNRFLMS-AEAFEHLKTQFDLNAETNACSINGNAPAEIDLRQMRTVTPIRMQGGCGSA 114 Query: 133 WAFSTTGTMEGQYMKNERTSISFSEQQLVDCSGPWGNNGCSGGLMENAYQYLKQFGLETE 192 WAFS E Y+ S+ +EQ+LVDC+ +GC G + +Y++ G+ E Sbjct: 115 WAFSGVAATESAYLAYRDQSLDLAEQELVDCA---SQHGCHGDTIPRGIEYIQHNGVVQE 171 Query: 193 SSYPYTAVEGQCRY--NKQLGVAKVTGYYTVHSGSEVELKNLVGARRPAAVAVDVES-DF 249 S Y Y A E CR ++ G++ Y ++ E L AV + ++ D Sbjct: 172 SYYRYVAREQSCRRPNAQRFGISNYCQIYPPNANKIREA--LAQTHSAIAVIIGIKDLDA 229 Query: 250 MMYRSGIYQSQTCSPLRVN-HAVLAVGYGTQGGTDYWIVKNSWGTYWGERGYIRMARN 306 + G Q + + N HAV VGY G DYWIV+NSW T WG+ GY A N Sbjct: 230 FRHYDGRTIIQRDNGYQPNYHAVNIVGYSNAQGVDYWIVRNSWDTNWGDNGYGYFAAN 287 >5VPK-A nrPDB Length = 223 Score = 121 bits (304), Expect = 4e-28, Method: Compositional matrix adjust. Identities = 71/202 (35%), Positives = 100/202 (49%), Gaps = 11/202 (5%) Query: 104 NNRAVPDKIDWRESGYVTEVKDQGNCGSCWAFSTTGTMEGQYMKNERTSISFSEQQLVDC 163 N+ VP ++D R VT ++ QG CGSCWAFS E Y+ TS+ SEQ+LVDC Sbjct: 7 NSVNVPSELDLRSLRTVTPIRMQGGCGSCWAFSGVAATESAYLAYRNTSLDLSEQELVDC 66 Query: 164 SGPWGNNGCSGGLMENAYQYLKQFGLETESSYPYTAVEGQCRYNKQLGVAKVTGYYTVHS 223 + +GC G + +Y++Q G+ E SYPY A E QCR ++ Y ++ Sbjct: 67 A---SQHGCHGDTIPRGIEYIQQNGVVEERSYPYVAREQQCRRPNSQHYG-ISNYCQIYP 122 Query: 224 GSEVELKNLVGARRPAAVAVDVESDFMMY-----RSGIYQSQTCSPLRVNHAVLAVGYGT 278 +++ + A + D + R+ I P HAV VGYG+ Sbjct: 123 PDVKQIREALTQTHTAIAVIIGIKDLRAFQHYDGRTIIQHDNGYQPNY--HAVNIVGYGS 180 Query: 279 QGGTDYWIVKNSWGTYWGERGY 300 G DYWIV+NSW T WG+ GY Sbjct: 181 TQGVDYWIVRNSWDTTWGDSGY 202 >5VCN-A nrPDB Length = 222 Score = 110 bits (275), Expect = 8e-25, Method: Compositional matrix adjust. Identities = 71/206 (34%), Positives = 100/206 (48%), Gaps = 9/206 (4%) Query: 105 NRAVPDKIDWRESGYVTEVKDQGNCGSCWAFSTTGTMEGQYMKNERTSISFSEQQLVDCS 164 N P +ID R+ VT ++ QG CGSCWAFS E Y+ S+ +EQ+LVDC+ Sbjct: 7 NGNAPAEIDLRQMRTVTPIRMQGGCGSCWAFSGVAATESAYLAYRNQSLDLAEQELVDCA 66 Query: 165 GPWGNNGCSGGLMENAYQYLKQFGLETESSYPYTAVEGQCRYN--KQLGVAKVTGYYTVH 222 +GC G + +Y++ G+ ES Y Y A E CR ++ G++ Y + Sbjct: 67 ---SQHGCHGDTIPRGIEYIQHNGVVQESYYRYVAREQSCRRPNAQRFGISNYCQIYPPN 123 Query: 223 SGSEVELKNLVGARRPAAVAVDVES-DFMMYRSGIYQSQTCSPLRVN-HAVLAVGYGTQG 280 + E L AV + ++ D + G Q + + N HAV VGY Sbjct: 124 ANKIREA--LAQTHSAIAVIIGIKDLDAFRHYDGRTIIQRDNGYQPNYHAVNIVGYSNAQ 181 Query: 281 GTDYWIVKNSWGTYWGERGYIRMARN 306 G DYWIV+NSW T WG+ GY A N Sbjct: 182 GVDYWIVRNSWDTNWGDNGYGYFAAN 207 >3PBH-A nrPDB Length = 317 Score = 104 bits (260), Expect = 4e-23, Method: Compositional matrix adjust. Identities = 74/244 (30%), Positives = 113/244 (46%), Gaps = 40/244 (16%) Query: 114 WRESGYVTEVKDQGNCGSCWAFSTTGTMEGQYM--KNERTSISFSEQQLVDCSGPWGNNG 171 W + + E++DQG+CGSCWAF + + N S+ S + L+ C G +G Sbjct: 74 WPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLTCCGSMCGDG 133 Query: 172 CSGGLMENAYQYLKQFGL----------------------ETESSYPYTAVEG---QCR- 205 C+GG A+ + + GL S P EG +C Sbjct: 134 CNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCTGEGDTPKCSK 193 Query: 206 -----YNKQLGVAKVTGY--YTVHSGSEVELKNLVGARRPAAVAVDVESDFMMYRSGIYQ 258 Y+ K GY Y+V S SE ++ + P A V SDF++Y+SG+YQ Sbjct: 194 ICEPGYSPTYKQDKHYGYNSYSV-SNSEKDIMAEIYKNGPVEGAFSVYSDFLLYKSGVYQ 252 Query: 259 SQTCSPLRVNHAVLAVGYGTQGGTDYWIVKNSWGTYWGERGYIRMARNRGNMCGIAS--L 316 T + HA+ +G+G + GT YW+V NSW T WG+ G+ ++ R + + CGI S + Sbjct: 253 HVT-GEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRGQ-DHCGIESEVV 310 Query: 317 ASLP 320 A +P Sbjct: 311 AGIP 314 >1CPJ-A nrPDB Length = 260 Score = 102 bits (254), Expect = 2e-22, Method: Compositional matrix adjust. Identities = 74/253 (29%), Positives = 113/253 (44%), Gaps = 42/253 (16%) Query: 108 VPDKID----WRESGYVTEVKDQGNCGSCWAFSTTGTMEGQYM--KNERTSISFSEQQLV 161 +P+ D W + +++DQG+CGSCWAF M + N R ++ S + L+ Sbjct: 7 LPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDLL 66 Query: 162 DCSGPWGNNGCSGGLMENAYQYLKQFGLETESSY-------PYT---------AVEGQC- 204 C G +GC+GG A+ + + GL + Y PYT C Sbjct: 67 TCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNGARPPCT 126 Query: 205 ------RYNKQLGVAKVTGY-------YTVHS--GSEVELKNLVGARRPAAVAVDVESDF 249 + NK T Y YT +S SE E+ + P A V SDF Sbjct: 127 GEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTVFSDF 186 Query: 250 MMYRSGIYQSQTCSPLRVNHAVLAVGYGTQGGTDYWIVKNSWGTYWGERGYIRMARNRGN 309 + Y+SG+Y+ + + HA+ +G+G + G YW+V NSW WG+ G+ ++ R N Sbjct: 187 LTYKSGVYKHEA-GDVMGGHAIRILGWGIENGVPYWLVANSWNADWGDNGFFKILRGE-N 244 Query: 310 MCGIAS--LASLP 320 CGI S +A +P Sbjct: 245 HCGIESEIVAGIP 257 >3CBK-A nrPDB Length = 266 Score = 100 bits (250), Expect = 7e-22, Method: Compositional matrix adjust. Identities = 71/249 (28%), Positives = 114/249 (45%), Gaps = 40/249 (16%) Query: 114 WRESGYVTEVKDQGNCGSCWAFSTTGTMEGQYM--KNERTSISFSEQQLVDCSGPWGNNG 171 W + + E++DQG+CGS WAF + + N S+ S + L+ C G +G Sbjct: 17 WPQCPTIKEIRDQGSCGSAWAFGAVEAISDRICIHTNAHVSVEVSAEDLLTCCGSMCGDG 76 Query: 172 CSGGLMENAYQYLKQFGLETESSY-------PYTAVEGQCR------------------- 205 C+GG A+ + + GL + Y PY+ + Sbjct: 77 CNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEAHVNGARPPCTGEGDTPKCSK 136 Query: 206 -----YNKQLGVAKVTGY--YTVHSGSEVELKNLVGARRPAAVAVDVESDFMMYRSGIYQ 258 Y+ K GY Y+V S SE ++ + P A V SDF++Y+SG+YQ Sbjct: 137 ICEPGYSPTYKQDKHYGYNSYSV-SNSEKDIMAEIYKNGPVEGAFSVYSDFLLYKSGVYQ 195 Query: 259 SQTCSPLRVNHAVLAVGYGTQGGTDYWIVKNSWGTYWGERGYIRMARNRGNMCGIAS--L 316 T + HA+ +G+G + GT YW+V NSW T WG+ G+ ++ R + + CGI S + Sbjct: 196 HVT-GEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRGQ-DHCGIESEVV 253 Query: 317 ASLPMVARF 325 A +P ++ Sbjct: 254 AGIPRTDQY 262 >1MIR-A nrPDB Length = 322 Score = 99.8 bits (247), Expect = 2e-21, Method: Compositional matrix adjust. Identities = 73/258 (28%), Positives = 114/258 (44%), Gaps = 42/258 (16%) Query: 108 VPDKID----WRESGYVTEVKDQGNCGSCWAFSTTGTMEGQYM--KNERTSISFSEQQLV 161 +P+ D W + +++DQG+CGS WAF M + N R ++ S + L+ Sbjct: 63 LPESFDAREQWSNCPTIAQIRDQGSCGSSWAFGAVEAMSDRICIHTNGRVNVEVSAEDLL 122 Query: 162 DCSGPWGNNGCSGGLMENAYQYLKQFGLETESSY-------PYT---------AVEGQC- 204 C G +GC+GG A+ + + GL + Y PYT C Sbjct: 123 TCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNGARPPCT 182 Query: 205 ------RYNKQLGVAKVTGY-------YTVHS--GSEVELKNLVGARRPAAVAVDVESDF 249 + NK T Y YT +S SE E+ + P A V SDF Sbjct: 183 GEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTVFSDF 242 Query: 250 MMYRSGIYQSQTCSPLRVNHAVLAVGYGTQGGTDYWIVKNSWGTYWGERGYIRMARNRGN 309 + Y+SG+Y+ + + HA+ +G+G + G YW+V NSW WG+ G+ ++ R N Sbjct: 243 LTYKSGVYKHEA-GDVMGGHAIRILGWGIENGVPYWLVANSWNADWGDNGFFKILRGE-N 300 Query: 310 MCGIAS--LASLPMVARF 325 CGI S +A +P ++ Sbjct: 301 HCGIESEIVAGIPRTQQY 318 >5I4H-B nrPDB Length = 112 Score = 89.4 bits (220), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 46/102 (45%), Positives = 58/102 (56%), Gaps = 5/102 (4%) Query: 226 EVELKNLVGARRPAAVAVDV-ESDFMMYRSGIYQSQTCSPLRVNHAVLAVGYGTQG---- 280 E L V P +VA+D F+ Y+ GIY CS ++H VL VGYG + Sbjct: 11 EKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESD 70 Query: 281 GTDYWIVKNSWGTYWGERGYIRMARNRGNMCGIASLASLPMV 322 YW+VKNSWG WG GY++MA++R N CGIAS AS P V Sbjct: 71 NNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV 112 >4HWY-A nrPDB Length = 340 Score = 88.6 bits (218), Expect = 3e-18, Method: Compositional matrix adjust. Identities = 69/242 (28%), Positives = 96/242 (39%), Gaps = 34/242 (14%) Query: 102 EANNRAVPDKID----WRESGYVTEVKDQGNCGSCWAFSTTGTMEGQYMK-NERTSISFS 156 E +P D W + ++ DQ CGSCWA + M ++ + S Sbjct: 88 EEARAPLPSSFDSAEAWPNCPTIPQIADQSACGSCWAVAAASAMSDRFCTMGGVQDVHIS 147 Query: 157 EQQLVDCSGPWGNNGCSGGLMENAYQYLKQFGLETESSYPYTAVE--------------- 201 L+ C G+ GC+GG + A+ Y GL ++ PY Sbjct: 148 AGDLLACCSDCGD-GCNGGDPDRAWAYFSSTGLVSDYCQPYPFPHCSHHSKSKNGYPPCS 206 Query: 202 ------GQCRYNKQLGVAKVTGYYTVHS----GSEVELKNLVGARRPAAVAVDVESDFMM 251 +C Y V Y + S G + ++ L R P VA DV DF+ Sbjct: 207 QFNFDTPKCNYTCDDPTIPVVNYRSWTSYALQGEDDYMRELF-FRGPFEVAFDVYEDFIA 265 Query: 252 YRSGIYQSQTCSPLRVNHAVLAVGYGTQGGTDYWIVKNSWGTYWGERGYIRMARNRGNMC 311 Y SG+Y + L HAV VG+GT G YW + NSW T WG GY + R + C Sbjct: 266 YNSGVYHHVSGQYLG-GHAVRLVGWGTSNGVPYWKIANSWNTEWGMDGYF-LIRRGSSEC 323 Query: 312 GI 313 GI Sbjct: 324 GI 325 >4I05-A nrPDB Length = 285 Score = 87.8 bits (216), Expect = 7e-18, Method: Compositional matrix adjust. Identities = 70/250 (28%), Positives = 100/250 (40%), Gaps = 42/250 (16%) Query: 105 NRAVPDKID----WRESGYVTEVKDQGNCGSCWAFSTTGTMEGQ--YMKNERTSISFSEQ 158 N +P D W + ++DQ CGSCWAF M + + ++ S Sbjct: 31 NVEIPSSFDSRKKWPRCKSIATIRDQSRCGSCWAFGAVEAMSDRSCIQSGGKQNVELSAV 90 Query: 159 QLVDCSGPWGNNGCSGGLMENAYQYLKQFGLETESS---------YPYTAVEGQCRYN-- 207 L+ C G GC GG++ A+ Y + G+ T SS YP+ E + Sbjct: 91 DLLSCCESCGL-GCEGGILGPAWDYWVKEGIVTGSSKENHAGCEPYPFPKCEHHTKGKYP 149 Query: 208 ------------KQLGVAKVTGYYT--VHSGS--------EVELKNLVGARRPAAVAVDV 245 KQ K YT H G E ++ + P V Sbjct: 150 PCGSKIYKTPRCKQTCQKKYKTPYTQDKHRGKSSYNVKNDEKAIQKEIMKYGPVEAGFTV 209 Query: 246 ESDFMMYRSGIYQSQTCSPLRVNHAVLAVGYGTQGGTDYWIVKNSWGTYWGERGYIRMAR 305 DF+ Y+SGIY+ T L HA+ +G+G + YW++ NSW WGE GY R+ R Sbjct: 210 YEDFLNYKSGIYKHITGETLG-GHAIRIIGWGVENKAPYWLIANSWNEDWGENGYFRIVR 268 Query: 306 NRGNMCGIAS 315 R + C I S Sbjct: 269 GR-DECSIES 277 >1DEU-A nrPDB Length = 277 Score = 87.0 bits (214), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 67/220 (30%), Positives = 95/220 (43%), Gaps = 30/220 (13%) Query: 108 VPDKIDWRES---GYVTEVKDQ---GNCGSCWAFSTTGTMEGQY---MKNERTSISFSEQ 158 +P DWR Y + ++Q CGSCWA ++T M + K S S Q Sbjct: 36 LPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQ 95 Query: 159 QLVDCSGPWGNNG-CSGGLMENAYQYLKQFGLETESSYPYTAVEGQCRYNKQLGVAKV-- 215 ++DC GN G C GG + + Y Q G+ E+ Y A + +C Q G Sbjct: 96 NVIDC----GNAGSCEGGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFK 151 Query: 216 ------------TGYYTVHSGSEVELKNLVGARRPAAVAVDVESDFMMYRSGIYQSQTCS 263 G Y SG E + + A P + + Y GIY ++ Sbjct: 152 ECHAIRNYTLWRVGDYGSLSGREKMMAEIY-ANGPISCGIMATERLANYTGGIY-AEYQD 209 Query: 264 PLRVNHAVLAVGYGTQGGTDYWIVKNSWGTYWGERGYIRM 303 +NH V G+G GT+YWIV+NSWG WGERG++R+ Sbjct: 210 TTYINHVVSVAGWGISDGTEYWIVRNSWGEPWGERGWLRI 249 >1EF7-A nrPDB Length = 242 Score = 87.0 bits (214), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 67/220 (30%), Positives = 95/220 (43%), Gaps = 30/220 (13%) Query: 108 VPDKIDWRES---GYVTEVKDQ---GNCGSCWAFSTTGTMEGQY---MKNERTSISFSEQ 158 +P DWR Y + ++Q CGSCWA ++T M + K S S Q Sbjct: 1 LPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQ 60 Query: 159 QLVDCSGPWGNNG-CSGGLMENAYQYLKQFGLETESSYPYTAVEGQCRYNKQLGVAKV-- 215 ++DC GN G C GG + + Y Q G+ E+ Y A + +C Q G Sbjct: 61 NVIDC----GNAGSCEGGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFK 116 Query: 216 ------------TGYYTVHSGSEVELKNLVGARRPAAVAVDVESDFMMYRSGIYQSQTCS 263 G Y SG E + + A P + + Y GIY ++ Sbjct: 117 ECHAIRNYTLWRVGDYGSLSGREKMMAEIY-ANGPISCGIMATERLANYTGGIY-AEYQD 174 Query: 264 PLRVNHAVLAVGYGTQGGTDYWIVKNSWGTYWGERGYIRM 303 +NH V G+G GT+YWIV+NSWG WGERG++R+ Sbjct: 175 TTYINHVVSVAGWGISDGTEYWIVRNSWGEPWGERGWLRI 214 >5OGQ-A nrPDB Length = 254 Score = 86.3 bits (212), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 69/247 (27%), Positives = 99/247 (40%), Gaps = 42/247 (17%) Query: 108 VPDKID----WRESGYVTEVKDQGNCGSCWAFSTTGTMEGQ--YMKNERTSISFSEQQLV 161 +P D W + ++DQ CGSCWAF M + + ++ S L+ Sbjct: 3 IPSSFDSRKKWPRCKSIATIRDQSRCGSCWAFGAVEAMSDRSCIQSGGKQNVELSAVDLL 62 Query: 162 DCSGPWGNNGCSGGLMENAYQYLKQFGLETESS---------YPYTAVEGQCRYN----- 207 C G GC GG++ A+ Y + G+ T SS YP+ E + Sbjct: 63 SCCESCGL-GCEGGILGPAWDYWVKEGIVTGSSKENHAGCEPYPFPKCEHHTKGKYPPCG 121 Query: 208 ---------KQLGVAKVTGYYT--VHSGS--------EVELKNLVGARRPAAVAVDVESD 248 KQ K YT H G E ++ + P V D Sbjct: 122 SKIYKTPRCKQTCQKKYKTPYTQDKHRGKSSYNVKNDEKAIQKEIMKYGPVEAGFTVYED 181 Query: 249 FMMYRSGIYQSQTCSPLRVNHAVLAVGYGTQGGTDYWIVKNSWGTYWGERGYIRMARNRG 308 F+ Y+SGIY+ T L HA+ +G+G + YW++ NSW WGE GY R+ R R Sbjct: 182 FLNYKSGIYKHITGETLG-GHAIRIIGWGVENKAPYWLIANSWNEDWGENGYFRIVRGR- 239 Query: 309 NMCGIAS 315 + C I S Sbjct: 240 DECSIES 246 >2DCB-A nrPDB Length = 256 Score = 85.5 bits (210), Expect = 3e-17, Method: Compositional matrix adjust. Identities = 68/259 (26%), Positives = 115/259 (44%), Gaps = 44/259 (16%) Query: 108 VPDKID----WRESGYVTEVKDQGNCGSCWAFSTTGTMEGQYM--KNERTSISFSEQQLV 161 +P+ D W + E++DQG+CGSCWAF + + N R ++ S + ++ Sbjct: 1 LPESFDAREQWPNCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHSNGRVNVEVSAEDML 60 Query: 162 DC--------------SGPWG---NNGCSGGLMENAYQYLKQFGL-----ETESSYPYTA 199 C SG W G G + N++ + + + S P Sbjct: 61 TCCGGECGDGCNGGFPSGAWNFWTKKGLVSGGLYNSHVGCRPYSIPPCEHHVNGSRPPCT 120 Query: 200 VEG---QCRYNKQLGVAKV--------TGYYTVHSGSEVELKNLVGARRPAAVAVDVESD 248 EG +C + G + Y+V + +E E+ + P A V SD Sbjct: 121 GEGDTPKCSKTCEPGYSPSYKEDKHFGCSSYSV-ANNEKEIMAEIYKNGPVEGAFSVYSD 179 Query: 249 FMMYRSGIYQSQTCSPLRVNHAVLAVGYGTQGGTDYWIVKNSWGTYWGERGYIRMARNRG 308 F++Y+SG+YQ + HA+ +G+G + GT YW+V NSW T WG+ G+ ++ R + Sbjct: 180 FLLYKSGVYQ-HVSGEIMGGHAIRILGWGVENGTPYWLVGNSWNTDWGDNGFFKILRGQ- 237 Query: 309 NMCGIAS--LASLPMVARF 325 + CGI S +A +P ++ Sbjct: 238 DHCGIESEIVAGMPCTHQY 256 >4I04-A nrPDB Length = 323 Score = 84.7 bits (208), Expect = 5e-17, Method: Compositional matrix adjust. Identities = 72/250 (28%), Positives = 101/250 (40%), Gaps = 42/250 (16%) Query: 105 NRAVPDKID----WRESGYVTEVKDQGNCGSCWAFSTTGTMEGQ--YMKNERTSISFSEQ 158 N +P D W + ++DQ CGS WAF M + + ++ S Sbjct: 69 NVEIPSSFDSRKKWPRCKSIATIRDQSRCGSSWAFGAVEAMSDRSCIQSGGKQNVELSAV 128 Query: 159 QLVDCSGPWGNNGCSGGLMENAYQYLKQFGLETESS---------YPYTAVEGQCRYN-- 207 L+ C G GC GG++ A+ Y + G+ T SS YP+ E + Sbjct: 129 DLLSCCESCGL-GCEGGILGPAWDYWVKEGIVTGSSKENHAGCEPYPFPKCEHHTKGKYP 187 Query: 208 ------------KQLGVAKVTGYYT--VHSG-SEVELKNLVGARR-------PAAVAVDV 245 KQ K YT H G S +KN A + P V Sbjct: 188 PCGSKIYKTPRCKQTCQKKYKTPYTQDKHRGKSSYNVKNDEKAIQKEIMKYGPVEAGFTV 247 Query: 246 ESDFMMYRSGIYQSQTCSPLRVNHAVLAVGYGTQGGTDYWIVKNSWGTYWGERGYIRMAR 305 DF+ Y+SGIY+ T L HA+ +G+G + YW++ NSW WGE GY R+ R Sbjct: 248 YEDFLNYKSGIYKHITGETLG-GHAIRIIGWGVENKAPYWLIANSWNEDWGENGYFRIVR 306 Query: 306 NRGNMCGIAS 315 R + C I S Sbjct: 307 GR-DECSIES 315 >4OEL-A nrPDB Length = 370 Score = 77.8 bits (190), Expect = 5e-15, Method: Compositional matrix adjust. Identities = 66/242 (27%), Positives = 110/242 (45%), Gaps = 29/242 (11%) Query: 39 HRRNIWEK--NVKHIQEHNLRHDLGLVTYTLGLNQFTDMTFEEFKAKYLTEMSRASDILS 96 H +N EK N + +HN + + +T T+ E++ L +M R S S Sbjct: 131 HLKNSQEKYSNRLYKYDHNFVKAINAIQ-----KSWTATTYMEYETLTLGDMIRRSGGHS 185 Query: 97 HGVP----------YEANNRAVPDKIDWRES---GYVTEVKDQGNCGSCWAFSTTGTMEG 143 +P + +P DWR +V+ V++Q +CGSC++F++ G +E Sbjct: 186 RKIPRPKPAPLTAEIQQKILHLPTSWDWRNVHGINFVSPVRNQASCGSCYSFASMGMLEA 245 Query: 144 --QYMKNERTSISFSEQQLVDCSGPWGNNGCSGGL-MENAYQYLKQFGLETESSYPYTAV 200 + + N + S Q++V CS GC GG A +Y + FGL E+ +PYT Sbjct: 246 RIRILTNNSQTPILSPQEVVSCSQ--YAQGCEGGFPYLIAGKYAQDFGLVEEACFPYTGT 303 Query: 201 EGQCRYNKQLGVAKVTGYYTV---HSG-SEVELKNLVGARRPAAVAVDVESDFMMYRSGI 256 + C+ + + Y+ V + G +E +K + P AVA +V DF+ Y+ GI Sbjct: 304 DSPCKMKEDCFRYYSSEYHYVGGFYGGCNEALMKLELVHHGPMAVAFEVYDDFLHYKKGI 363 Query: 257 YQ 258 Y Sbjct: 364 YH 365 >1CSB-B nrPDB Length = 205 Score = 77.0 bits (188), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 61/205 (29%), Positives = 93/205 (45%), Gaps = 38/205 (18%) Query: 151 TSISFSEQQLVDCSGPWGNNGCSGGLMENAYQYLKQFGL--------------------- 189 S+ S + L+ C G +GC+GG A+ + + GL Sbjct: 1 VSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCE 60 Query: 190 -ETESSYPYTAVEG---QCR------YNKQLGVAKVTGY--YTVHSGSEVELKNLVGARR 237 S P EG +C Y+ K GY Y+V S SE ++ + Sbjct: 61 HHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSV-SNSEKDIMAEIYKNG 119 Query: 238 PAAVAVDVESDFMMYRSGIYQSQTCSPLRVNHAVLAVGYGTQGGTDYWIVKNSWGTYWGE 297 P A V SDF++Y+SG+YQ T + HA+ +G+G + GT YW+V NSW T WG+ Sbjct: 120 PVEGAFSVYSDFLLYKSGVYQHVT-GEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGD 178 Query: 298 RGYIRMARNRGNMCGIAS--LASLP 320 G+ ++ R + + CGI S +A +P Sbjct: 179 NGFFKILRGQ-DHCGIESEVVAGIP 202 >4CDF-B nrPDB Length = 166 Score = 75.9 bits (185), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 50/161 (31%), Positives = 82/161 (50%), Gaps = 12/161 (7%) Query: 108 VPDKIDWRES---GYVTEVKDQGNCGSCWAFSTTGTMEG--QYMKNERTSISFSEQQLVD 162 +P DWR +V+ V++Q +CGSC++F++ G +E + + N + S Q++V Sbjct: 3 LPTSWDWRNVHGINFVSPVRNQASCGSCYSFASMGMLEARIRILTNNSQTPILSPQEVVS 62 Query: 163 CSGPWGNNGCSGGL-MENAYQYLKQFGLETESSYPYTAVEGQCRYNKQLGVAKVTGYYTV 221 CS GC GG A +Y + FGL E+ +PYT + C+ + + Y+ V Sbjct: 63 CS--QYAQGCEGGFPYLIAGKYAQDFGLVEEACFPYTGTDSPCKMKEDCFRYYSSEYHYV 120 Query: 222 ---HSG-SEVELKNLVGARRPAAVAVDVESDFMMYRSGIYQ 258 + G +E +K + P AVA +V DF+ Y+ GIY Sbjct: 121 GGFYGGCNEALMKLELVHHGPMAVAFEVYDDFLHYKKGIYH 161 >1SP4-B nrPDB Length = 205 Score = 69.7 bits (169), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 36/98 (36%), Positives = 57/98 (58%), Gaps = 4/98 (4%) Query: 225 SEVELKNLVGARRPAAVAVDVESDFMMYRSGIYQSQTCSPLRVNHAVLAVGYGTQGGTDY 284 +E E+ + P A V SDF++Y+SG+YQ + HA+ +G+G + GT Y Sbjct: 108 NEKEIMAEIYKNGPVEGAFSVYSDFLLYKSGVYQ-HVSGEIMGGHAIRILGWGVENGTPY 166 Query: 285 WIVKNSWGTYWGERGYIRMARNRGNMCGIAS--LASLP 320 W+V NSW T WG+ G+ ++ R + + CGI S +A +P Sbjct: 167 WLVGNSWNTDWGDNGFFKILRGQ-DHCGIESEIVAGMP 203 >4OEM-B nrPDB Length = 70 Score = 65.9 bits (159), Expect = 2e-11, Method: Composition-based stats. Identities = 33/52 (63%), Positives = 36/52 (69%), Gaps = 3/52 (5%) Query: 268 NHAVLAVGYGTQG--GTDYWIVKNSWGTYWGERGYIRMARNRGNMCGIASLA 317 NHAVL VGYGT G DYWIVKNSWGT WGE GY R+ R + C I S+A Sbjct: 10 NHAVLLVGYGTDSASGMDYWIVKNSWGTGWGENGYFRIRRGT-DECAIESIA 60 >3CH2-X nrPDB Length = 265 Score = 59.3 bits (142), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 54/216 (25%), Positives = 86/216 (39%), Gaps = 34/216 (15%) Query: 122 EVKDQGNCGSCWAFSTTGTMEGQYMKNERTSISFSEQQLVDCSGPWGNNGCSGGLMENAY 181 +V+DQGNC + W F++ +E S + +C + C G + Sbjct: 23 QVEDQGNCDTSWIFASKYHLETIRCMKGYEPTKISALYVANCYKGEHKDRCDEGSSPMEF 82 Query: 182 -QYLKQFG-LETESSYPYTAVE------------------GQCRYNKQLGVAKVTGYYTV 221 Q ++ +G L ES+YPY V+ G+ +NK + YT Sbjct: 83 LQIIEDYGFLPAESNYPYNYVKVGEQCPKVEDHWMNLWDNGKILHNKNEPNSLDGKGYTA 142 Query: 222 HSGSE--------VELKNLVGARRPAAVAVDVESDFMMYR-SGIYQSQTCSPLRVNHAVL 272 + V++ + + +A + M Y SG C +HAV Sbjct: 143 YESERFHDNMDAFVKIIKTEVMNKGSVIAYIKAENVMGYEFSGKKVQNLCGDDTADHAVN 202 Query: 273 AVGYGTQGGTD-----YWIVKNSWGTYWGERGYIRM 303 VGYG ++ YWIV+NSWG YWG+ GY ++ Sbjct: 203 IVGYGNYVNSEGEKKSYWIVRNSWGPYWGDEGYFKV 238 >2L95-A nrPDB Length = 80 Score = 55.1 bits (131), Expect = 5e-08, Method: Composition-based stats. Identities = 23/67 (34%), Positives = 41/67 (61%) Query: 17 NDDLWHQWKRMYNKEYNGADDQHRRNIWEKNVKHIQEHNLRHDLGLVTYTLGLNQFTDMT 76 +D+ W ++K ++K Y +D RR I+ ++ I+EHN + + G VT+ +G+N D+T Sbjct: 6 SDEEWVEYKSKFDKNYEAEEDLMRRRIYAESKARIEEHNRKFEKGEVTWKMGINHLADLT 65 Query: 77 FEEFKAK 83 EEF + Sbjct: 66 PEEFAQR 72 >5FPW-A nrPDB Length = 321 Score = 54.3 bits (129), Expect = 7e-08, Method: Compositional matrix adjust. Identities = 70/277 (25%), Positives = 107/277 (38%), Gaps = 36/277 (12%) Query: 71 QFTDMTFEEFKAKYLTEMSRASDILSHGVPYEANNRAVPDKID----WRESGYVTEVKDQ 126 + ++TF E K + + S + E +P+ D W + E+ DQ Sbjct: 38 KMQNITFAEAKRLTGAWIQKTSSLPPVRFTEEQLRTELPESFDSAEKWPNCPTIREIADQ 97 Query: 127 GNCGSCWAFSTTGTMEGQYMK-NERTSISFSEQQLVDCSGPWGNNGCSGGLMENAYQYLK 185 C + WA ST + +Y + S L+ C GC GG A++Y Sbjct: 98 SACRASWAVSTASVISDRYCTVGGVQQLRISAAHLLSCCKQ-CGGGCKGGFPGFAWRYYV 156 Query: 186 QFGLETE--SSYPYTAVEGQ---------CRYN------------KQLGVAKVTG---YY 219 ++G+ + YP+ E + +YN K + + K G Y Sbjct: 157 EYGIASSYCQPYPFPHCEHRGAQGNKTPCSKYNFDTPKCQATCTDKSIPLVKYRGSATYL 216 Query: 220 TVHSGSEVELKNLVGARRPAAVAVDVESDFMMYRSGIYQSQTCSPLRVNHAVLAVGYGTQ 279 +H E + K + P V +D Y+SG+Y+ L AV VG+G Sbjct: 217 LLHG--EEDYKRELYFNGPFVAVFYVYTDLFAYKSGVYRHVDGDFLG-GTAVKVVGWGKL 273 Query: 280 GGTDYWIVKNSWGTYWGERGYIRMARNRGNMCGIASL 316 GT YW V N+W T WG GY+ + R N C I L Sbjct: 274 NGTPYWKVANTWDTDWGMDGYLLILRGN-NECNIEHL 309 >3OIS-A nrPDB Length = 291 Score = 38.9 bits (89), Expect = 0.003, Method: Compositional matrix adjust. Identities = 50/227 (22%), Positives = 87/227 (38%), Gaps = 41/227 (18%) Query: 107 AVPDKIDWRESGYVTEVKDQGNCGSCWAFSTTGTMEGQYMKNE--------RTSISFSEQ 158 A+P K+D +V DQG GSC A + ++ + + ++ R I ++E+ Sbjct: 56 ALPPKVDLTPP---FQVYDQGRIGSCTANALAAAIQFERIHDKQSPEFIPSRLFIYYNER 112 Query: 159 QLVDCSGPWGNNGCSGGLMENAYQYLKQFGLETESSYPYTAVEGQCRYNKQLGVAKVTGY 218 ++ N SG ++ + + L + G+ E +PY R + A + Sbjct: 113 KIEGHV-----NYDSGAMIRDGIKVLHKLGVCPEKEWPYGDTPADPRTEEFPPGAPASKK 167 Query: 219 YTVHSGSEVELKNLVGARRPA----------AVAVDVESDFMMYRSGIYQSQTCSPLRV- 267 + + + + R A AV F +Y S + P+R+ Sbjct: 168 PSDQCYKDAQNYKITEYSRVAQDIDHLKACLAVGSPFVFGFSVYNSWV--GNNSLPVRIP 225 Query: 268 ----------NHAVLAVGYGTQGGTDYWIVKNSWGTYWGERGYIRMA 304 HAVL VGY + ++ ++NSWG GE GY M Sbjct: 226 LPTKNDTLEGGHAVLCVGYDDE--IRHFRIRNSWGNNVGEDGYFWMP 270 >2POC-A nrPDB Length = 367 Score = 32.7 bits (73), Expect = 0.20, Method: Compositional matrix adjust. Identities = 21/79 (26%), Positives = 39/79 (49%), Gaps = 4/79 (5%) Query: 241 VAVDVESDFMMYRSGIYQSQTCSPL----RVNHAVLAVGYGTQGGTDYWIVKNSWGTYWG 296 V+V++ SDF+ RS +++ TC + ++LA+ Y + G + NS G+ Sbjct: 80 VSVELASDFLDRRSPVFRDDTCVFVSQSGETADSILALQYCLERGALTVGIVNSVGSSMS 139 Query: 297 ERGYIRMARNRGNMCGIAS 315 + + + N G G+AS Sbjct: 140 RQTHCGVHINAGPEIGVAS 158 >4D59-A nrPDB Length = 406 Score = 32.3 bits (72), Expect = 0.25, Method: Compositional matrix adjust. Identities = 51/212 (24%), Positives = 79/212 (37%), Gaps = 35/212 (16%) Query: 118 GYVTEVKDQGNCGSCWAFSTTGTMEGQYMKNERTSISFSEQQL----VDCSGPWGNNGCS 173 G T K+QG+ + W+FS T+E + SE+ L W + S Sbjct: 11 GLTTPAKNQGSLNTAWSFSGMSTLEAYLKLKGYGTYDLSEEHLRWWATGGKYGWNLDDMS 70 Query: 174 GGLMENAYQYLKQF-GLETESSYPYT-AVEGQCRYNKQLGVAKVTGYYTVHSGSEV-ELK 230 G A YL + G + E PY E Q G K + T + V ++ Sbjct: 71 GSSNVTAIGYLTAWAGPKLEKDIPYNLKSEAQ-------GATKPSNMDTAPTQFNVTDVV 123 Query: 231 NLVGARRPAAVAV----DVESDFMMYRSGIYQSQT---CSPLR--VNHAVLAVGYGTQGG 281 L + A+ V S + Y + + +T C+ R +NHAV VG+ Sbjct: 124 RLNKDKETVKNAIMQYGSVTSGYAHYSTYFNKDETAYNCTNKRAPLNHAVAIVGWDDNYS 183 Query: 282 TD------------YWIVKNSWGTYWGERGYI 301 D W+VK+SWG + +G+ Sbjct: 184 KDNFASDVKPESNGAWLVKSSWGEFNSMKGFF 215 >4CI7-A nrPDB Length = 470 Score = 32.3 bits (72), Expect = 0.28, Method: Compositional matrix adjust. Identities = 51/212 (24%), Positives = 79/212 (37%), Gaps = 35/212 (16%) Query: 118 GYVTEVKDQGNCGSCWAFSTTGTMEGQYMKNERTSISFSEQQL----VDCSGPWGNNGCS 173 G T K+QG+ + W+FS T+E + SE+ L W + S Sbjct: 75 GLTTPAKNQGSLNTAWSFSGMSTLEAYLKLKGYGTYDLSEEHLRWWATGGKYGWNLDDMS 134 Query: 174 GGLMENAYQYLKQF-GLETESSYPYT-AVEGQCRYNKQLGVAKVTGYYTVHSGSEV-ELK 230 G A YL + G + E PY E Q G K + T + V ++ Sbjct: 135 GSSNVTAIGYLTAWAGPKLEKDIPYNLKSEAQ-------GATKPSNMDTAPTQFNVTDVV 187 Query: 231 NLVGARRPAAVAV----DVESDFMMYRSGIYQSQT---CSPLR--VNHAVLAVGYGTQGG 281 L + A+ V S + Y + + +T C+ R +NHAV VG+ Sbjct: 188 RLNKDKETVKNAIMQYGSVTSGYAHYSTYFNKDETAYNCTNKRAPLNHAVAIVGWDDNYS 247 Query: 282 TD------------YWIVKNSWGTYWGERGYI 301 D W+VK+SWG + +G+ Sbjct: 248 KDNFASDVKPESNGAWLVKSSWGEFNSMKGFF 279 >5WDK-A nrPDB Length = 401 Score = 30.0 bits (66), Expect = 1.6, Method: Compositional matrix adjust. Identities = 11/38 (28%), Positives = 21/38 (55%) Query: 120 VTEVKDQGNCGSCWAFSTTGTMEGQYMKNERTSISFSE 157 +T VK+Q G+CW +S+ +E + ++ + SE Sbjct: 40 ITSVKNQNRAGTCWCYSSYSFLESELLRMGKGEYDLSE 77 >4V0R-A nrPDB Length = 892 Score = 30.0 bits (66), Expect = 1.6, Method: Compositional matrix adjust. Identities = 21/68 (30%), Positives = 32/68 (47%), Gaps = 2/68 (2%) Query: 66 TLGLNQFTDM-TFEEFKAKYLTEMSRASDILSHGVPYEANNRAVPDKIDWRESGYVTEVK 124 TLG N+ + T EEF K T + + + + Y++ AV D+ W+ E+ Sbjct: 380 TLGRNKRPRLCTREEFTKKVRTNAAMGA-VFTEENQYDSAKAAVEDEEFWKLVDRERELH 438 Query: 125 DQGNCGSC 132 G CGSC Sbjct: 439 KLGKCGSC 446 >1Z5U-A nrPDB Length = 214 Score = 29.6 bits (65), Expect = 1.9, Method: Compositional matrix adjust. Identities = 18/66 (27%), Positives = 29/66 (43%), Gaps = 1/66 (1%) Query: 200 VEGQCRYNKQLGVAKVTGYYTVHSGSEVELKNLVGARRPAAVAVDVESDFMMYRSGIYQ- 258 V N VAK+ VH S +++N + R P AV D++ + G ++ Sbjct: 2 VSSPSTLNPGTNVAKLAEQAPVHWVSVAQIENSLTGRPPMAVGFDIDDTVLFSSPGFWRG 61 Query: 259 SQTCSP 264 +T SP Sbjct: 62 KKTYSP 67 >4K7C-A nrPDB Length = 446 Score = 29.6 bits (65), Expect = 2.1, Method: Compositional matrix adjust. Identities = 14/36 (38%), Positives = 19/36 (52%), Gaps = 1/36 (2%) Query: 267 VNHAVLAVGYG-TQGGTDYWIVKNSWGTYWGERGYI 301 + HA++ G G W V+NSWG GE+GY Sbjct: 362 MTHAMVLTGVDLVDGKPTKWKVENSWGEKVGEKGYF 397 >4C11-A nrPDB Length = 638 Score = 28.1 bits (61), Expect = 5.3, Method: Compositional matrix adjust. Identities = 20/68 (29%), Positives = 32/68 (47%), Gaps = 2/68 (2%) Query: 66 TLGLNQFTDM-TFEEFKAKYLTEMSRASDILSHGVPYEANNRAVPDKIDWRESGYVTEVK 124 TLG N+ + T EEF K T + + + + +++ AV D+ W+ E+ Sbjct: 121 TLGRNKRPRLCTREEFTKKVRTNAAMGA-VFTEENQWDSAKAAVEDEEFWKLVDRERELH 179 Query: 125 DQGNCGSC 132 G CGSC Sbjct: 180 KLGKCGSC 187 >4Z04-A nrPDB Length = 131 Score = 27.7 bits (60), Expect = 7.3, Method: Compositional matrix adjust. Identities = 14/39 (35%), Positives = 20/39 (51%), Gaps = 3/39 (7%) Query: 251 MYRSGIYQSQTCSPLRVNHAVLA---VGYGTQGGTDYWI 286 M +S + SPL + HA+ VGYG G ++WI Sbjct: 20 MKKSRAFYDAALSPLGIGHAMEFGDWVGYGRNGKPEFWI 58 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 2O6X-A nrPDB 459 e-130 1CJL-A nrPDB 396 e-111 2C0Y-A nrPDB 395 e-110 7PCK-A nrPDB 393 e-110 3QT4-A nrPDB 380 e-106 3QJ3-A nrPDB 368 e-102 6CZS-A nrPDB 359 e-99 4QRX-A nrPDB 349 9e-97 5EF4-A nrPDB 342 1e-94 1PCI-A nrPDB 341 2e-94 3HWN-A nrPDB 340 7e-94 3OF9-A nrPDB 315 2e-86 3KFQ-A nrPDB 313 7e-86 4P6E-A nrPDB 308 2e-84 4BS5-A nrPDB 305 2e-83 5JA7-A nrPDB 303 5e-83 1S4V-A nrPDB 301 3e-82 2VHS-A nrPDB 300 6e-82 6BKI-A nrPDB 296 6e-81 3P5W-A nrPDB 295 2e-80 2FO5-A nrPDB 292 1e-79 1CQD-A nrPDB 291 2e-79 1NB3-A nrPDB 291 2e-79 1AEC-A nrPDB 288 3e-78 3PDF-A nrPDB 288 3e-78 5JT8-A nrPDB 286 7e-78 4YYR-A nrPDB 285 2e-77 1IWD-A nrPDB 284 4e-77 4YYW-A nrPDB 283 8e-77 2ACT-A nrPDB 283 8e-77 2PNS-A nrPDB 282 1e-76 3F75-A nrPDB 281 2e-76 3BCN-A nrPDB 281 3e-76 1YAL-A nrPDB 277 4e-75 1O0E-A nrPDB 276 1e-74 2BDZ-A nrPDB 272 1e-73 1PPO-A nrPDB 269 1e-72 6MIS-A nrPDB 269 1e-72 2CIO-A nrPDB 266 1e-71 1XKG-A nrPDB 265 2e-71 5A24-A nrPDB 263 8e-71 4YYQ-A nrPDB 263 1e-70 1GEC-E nrPDB 259 1e-69 2B1M-A nrPDB 258 2e-69 1JQP-A nrPDB 254 4e-68 1ICF-A nrPDB 252 1e-67 3U8E-A nrPDB 250 7e-67 3PBH-A nrPDB 249 2e-66 6EXO-A nrPDB 248 3e-66 3IOQ-A nrPDB 245 2e-65 4PI3-A nrPDB 244 5e-65 3CBK-A nrPDB 243 6e-65 4HWY-A nrPDB 242 1e-64 1MIR-A nrPDB 239 9e-64 1CPJ-A nrPDB 237 4e-63 3BPF-A nrPDB 237 6e-63 3BPM-A nrPDB 228 3e-60 5VPK-A nrPDB 226 1e-59 4I05-A nrPDB 223 8e-59 1M6D-A nrPDB 222 1e-58 4I04-A nrPDB 221 3e-58 5OGQ-A nrPDB 217 4e-57 5VCN-A nrPDB 217 5e-57 4OEL-A nrPDB 217 6e-57 2DCB-A nrPDB 214 5e-56 5FPW-A nrPDB 208 3e-54 1DEU-A nrPDB 189 2e-48 1EF7-A nrPDB 185 2e-47 1CSB-B nrPDB 174 4e-44 4CDF-B nrPDB 172 1e-43 5I4H-A nrPDB 171 3e-43 3CH2-X nrPDB 153 9e-38 1SP4-B nrPDB 142 2e-34 5I4H-B nrPDB 140 6e-34 2L95-A nrPDB 86 2e-17 4OEM-B nrPDB 82 2e-16 Sequences not found previously or not previously below threshold: 4CI7-A nrPDB 65 4e-11 4D59-A nrPDB 65 5e-11 3OIS-A nrPDB 63 1e-10 4K7C-A nrPDB 43 2e-04 5WDK-A nrPDB 38 0.004 2QGM-A nrPDB 36 0.021 2CB5-A nrPDB 34 0.091 5L22-B nrPDB 31 0.66 1QHM-A nrPDB 31 0.67 1H18-A nrPDB 31 0.67 1A6R-A nrPDB 30 1.3 2Z51-A nrPDB 30 1.5 1V9N-A nrPDB 29 3.0 1L9N-A nrPDB 29 3.1 3B55-A nrPDB 29 3.1 1G0D-A nrPDB 29 3.2 2G7H-A nrPDB 28 3.9 4G6U-A nrPDB 28 4.0 1UT9-A nrPDB 28 4.1 2HCZ-X nrPDB 28 4.3 2JNV-A nrPDB 28 7.3 3S9V-A nrPDB 27 8.7 >2O6X-A nrPDB Length = 310 Score = 459 bits (1180), Expect = e-130, Method: Composition-based stats. Identities = 301/310 (97%), Positives = 302/310 (97%) Query: 17 NDDLWHQWKRMYNKEYNGADDQHRRNIWEKNVKHIQEHNLRHDLGLVTYTLGLNQFTDMT 76 NDDLWHQWKRMYNKEYNGADDQHRRNIWEKNVKHIQEHNLRHDLGLVTYTLGLNQFTDMT Sbjct: 1 NDDLWHQWKRMYNKEYNGADDQHRRNIWEKNVKHIQEHNLRHDLGLVTYTLGLNQFTDMT 60 Query: 77 FEEFKAKYLTEMSRASDILSHGVPYEANNRAVPDKIDWRESGYVTEVKDQGNCGSCWAFS 136 FEEFKAKYLTEMSRASDILSHGVPYEANNRAVPDKIDWRESGYVTEVKDQGNCGS WAFS Sbjct: 61 FEEFKAKYLTEMSRASDILSHGVPYEANNRAVPDKIDWRESGYVTEVKDQGNCGSGWAFS 120 Query: 137 TTGTMEGQYMKNERTSISFSEQQLVDCSGPWGNNGCSGGLMENAYQYLKQFGLETESSYP 196 TTGTMEGQYMKNERTSISFSEQQLVDCS PWGNNGC GGLMENAYQYLKQFGLETESSYP Sbjct: 121 TTGTMEGQYMKNERTSISFSEQQLVDCSRPWGNNGCGGGLMENAYQYLKQFGLETESSYP 180 Query: 197 YTAVEGQCRYNKQLGVAKVTGYYTVHSGSEVELKNLVGARRPAAVAVDVESDFMMYRSGI 256 YTAVEGQCRYNKQLGVAKVTG+YTVHSGSEVELKNLVGA PAAVAVDVESDFMMYRSGI Sbjct: 181 YTAVEGQCRYNKQLGVAKVTGFYTVHSGSEVELKNLVGAEGPAAVAVDVESDFMMYRSGI 240 Query: 257 YQSQTCSPLRVNHAVLAVGYGTQGGTDYWIVKNSWGTYWGERGYIRMARNRGNMCGIASL 316 YQSQTCSPLRVNHAVLAVGYGTQGGTDYWIVKNSWG WGERGYIRM RNRGNMCGIASL Sbjct: 241 YQSQTCSPLRVNHAVLAVGYGTQGGTDYWIVKNSWGLSWGERGYIRMVRNRGNMCGIASL 300 Query: 317 ASLPMVARFP 326 ASLPMVARFP Sbjct: 301 ASLPMVARFP 310 >1CJL-A nrPDB Length = 312 Score = 396 bits (1018), Expect = e-111, Method: Composition-based stats. Identities = 141/316 (44%), Positives = 185/316 (58%), Gaps = 15/316 (4%) Query: 16 SNDDLWHQWKRMYNKEYNGADDQHRRNIWEKNVKHIQEHNLRHDLGLVTYTLGLNQFTDM 75 S + W +WK M+N+ Y ++ RR +WEKN+K I+ HN + G ++T+ +N F DM Sbjct: 3 SLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIELHNQEYREGKHSFTMAMNAFGDM 62 Query: 76 TFEEFKAKY---LTEMSRASDILSHGVPYEANNRAVPDKIDWRESGYVTEVKDQGNCGSC 132 T EEF+ R + + YEA P +DWRE GYVT VK+QG CGS Sbjct: 63 TSEEFRQVMNGLQNRKPRKGKVFQEPLFYEA-----PRSVDWREKGYVTPVKNQGQCGSS 117 Query: 133 WAFSTTGTMEGQYMKNERTSISFSEQQLVDCSGPWGNNGCSGGLMENAYQYLK-QFGLET 191 WAFS TG +EGQ + IS SEQ LVDCSGP GN GC+GGLM+ A+QY++ GL++ Sbjct: 118 WAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPEGNEGCNGGLMDYAFQYVQDNGGLDS 177 Query: 192 ESSYPYTAVEGQCRYNKQLGVAKVTGYYTVHSGSEVELKNLVGARRPAAVAVDV-ESDFM 250 E SYPY A E C+YN + VA G+ + E L V P +VA+D F+ Sbjct: 178 EESYPYEATEESCKYNPKYSVANDAGFVDIPK-QEKALMKAVATVGPISVAIDAGHESFL 236 Query: 251 MYRSGIYQSQTCSPLRVNHAVLAVGYGTQ----GGTDYWIVKNSWGTYWGERGYIRMARN 306 Y+ GIY CS ++H VL VGYG + G YW+VKNSWG WG GY++MA++ Sbjct: 237 FYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDGNKYWLVKNSWGEEWGMGGYVKMAKD 296 Query: 307 RGNMCGIASLASLPMV 322 R N CGIAS AS P V Sbjct: 297 RRNHCGIASAASYPTV 312 >2C0Y-A nrPDB Length = 315 Score = 395 bits (1014), Expect = e-110, Method: Composition-based stats. Identities = 140/310 (45%), Positives = 189/310 (60%), Gaps = 8/310 (2%) Query: 18 DDLWHQWKRMYNKEYNGADDQH-RRNIWEKNVKHIQEHNLRHDLGLVTYTLGLNQFTDMT 76 D WH WK+ Y K+Y +++ RR IWEKN+K + HNL H +G+ +Y LG+N DMT Sbjct: 9 DHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFVMLHNLEHSMGMHSYDLGMNHLGDMT 68 Query: 77 FEEFKAKYLTEMSRASDILSHGVPYEAN-NRAVPDKIDWRESGYVTEVKDQGNCGSCWAF 135 EE + L R + Y++N NR +PD +DWRE G VTEVK QG+CG+ WAF Sbjct: 69 SEEVMS--LMSSLRVPSQWQRNITYKSNPNRILPDSVDWREKGCVTEVKYQGSCGAAWAF 126 Query: 136 STTGTMEGQYMKNERTSISFSEQQLVDCSG-PWGNNGCSGGLMENAYQYL-KQFGLETES 193 S G +E Q +S S Q LVDCS +GN GC+GG M A+QY+ G+++++ Sbjct: 127 SAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDA 186 Query: 194 SYPYTAVEGQCRYNKQLGVAKVTGYYTVHSGSEVELKNLVGARRPAAVAVDV-ESDFMMY 252 SYPY A++ +C+Y+ + A + Y + G E LK V + P +V VD F +Y Sbjct: 187 SYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKEAVANKGPVSVGVDARHPSFFLY 246 Query: 253 RSGIYQSQTCSPLRVNHAVLAVGYGTQGGTDYWIVKNSWGTYWGERGYIRMARNRGNMCG 312 RSG+Y +C+ VNH VL VGYG G +YW+VKNSWG +GE GYIRMARN+GN CG Sbjct: 247 RSGVYYEPSCTQ-NVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARNKGNHCG 305 Query: 313 IASLASLPMV 322 IAS S P + Sbjct: 306 IASFPSYPEI 315 >7PCK-A nrPDB Length = 314 Score = 393 bits (1011), Expect = e-110, Method: Composition-based stats. Identities = 140/309 (45%), Positives = 181/309 (58%), Gaps = 6/309 (1%) Query: 18 DDLWHQWKRMYNKEYNGA-DDQHRRNIWEKNVKHIQEHNLRHDLGLVTYTLGLNQFTDMT 76 D W WK+ + K+YN D+ RR IWEKN+K+I HNL LG+ TY L +N DMT Sbjct: 8 DTHWELWKKTHRKQYNNKVDEISRRLIWEKNLKYISIHNLEASLGVHTYELAMNHLGDMT 67 Query: 77 FEEFKAKYLTEMSRASDILSHGVPYEAN-NRAVPDKIDWRESGYVTEVKDQGNCGSCWAF 135 EE K S S+ Y PD +D+R+ GYVT VK+QG CGSCWAF Sbjct: 68 SEEVVQKMTGLKVPLSHSRSNDTLYIPEWEGRAPDSVDYRKKGYVTPVKNQGQCGSCWAF 127 Query: 136 STTGTMEGQYMKNERTSISFSEQQLVDCSGPWGNNGCSGGLMENAYQYLK-QFGLETESS 194 S+ G +EGQ K ++ S Q LVDC N+GC GG M NA+QY++ G+++E + Sbjct: 128 SSVGALEGQLKKKTGKLLNLSPQNLVDCVSE--NDGCGGGYMTNAFQYVQKNRGIDSEDA 185 Query: 195 YPYTAVEGQCRYNKQLGVAKVTGYYTVHSGSEVELKNLVGARRPAAVAVDVE-SDFMMYR 253 YPY E C YN AK GY + G+E LK V P +VA+D + F Y Sbjct: 186 YPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKALKRAVARVGPVSVAIDASLTSFQFYS 245 Query: 254 SGIYQSQTCSPLRVNHAVLAVGYGTQGGTDYWIVKNSWGTYWGERGYIRMARNRGNMCGI 313 G+Y ++C+ +NHAVLAVGYG Q G +WI+KNSWG WG +GYI MARN+ N CGI Sbjct: 246 KGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILMARNKNNACGI 305 Query: 314 ASLASLPMV 322 A+LAS P + Sbjct: 306 ANLASFPKM 314 >3QT4-A nrPDB Length = 329 Score = 380 bits (975), Expect = e-106, Method: Composition-based stats. Identities = 132/306 (43%), Positives = 184/306 (60%), Gaps = 3/306 (0%) Query: 19 DLWHQWKRMYNKEYNGADDQHRRN-IWEKNVKHIQEHNLRHDLGLVTYTLGLNQFTDMTF 77 + W Q+K + K Y+ ++ RR I++ NV I EHN + + G VTY+ +NQF DM+ Sbjct: 25 EQWSQFKLTHKKSYSSPIEEIRRQLIFKDNVAKIAEHNAKFEKGEVTYSKAMNQFGDMSK 84 Query: 78 EEFKAKY-LTEMSRASDILSHGVPYEANNRAVPDKIDWRESGYVTEVKDQGNCGSCWAFS 136 EEF A + + + +PY ++ + + +DWR V+EVKDQG CGS W+FS Sbjct: 85 EEFLAYVNRGKAQKPKHPENLRMPYVSSKKPLAASVDWRS-NAVSEVKDQGQCGSSWSFS 143 Query: 137 TTGTMEGQYMKNERTSISFSEQQLVDCSGPWGNNGCSGGLMENAYQYLKQFGLETESSYP 196 TTG +EGQ S SEQ L+DCS +GN GC GG M++A+ Y+ +G+ +ES+YP Sbjct: 144 TTGAVEGQLALQRGRLTSLSEQNLIDCSSSYGNAGCDGGWMDSAFSYIHDYGIMSESAYP 203 Query: 197 YTAVEGQCRYNKQLGVAKVTGYYTVHSGSEVELKNLVGARRPAAVAVDVESDFMMYRSGI 256 Y A CR++ V ++GYY + SG E L + VG P AVA+D + Y G+ Sbjct: 204 YEAQGDYCRFDSSQSVTTLSGYYDLPSGDENSLADAVGQAGPVAVAIDATDELQFYSGGL 263 Query: 257 YQSQTCSPLRVNHAVLAVGYGTQGGTDYWIVKNSWGTYWGERGYIRMARNRGNMCGIASL 316 + QTC+ +NH VL VGYG+ G DYWI+KNSWG+ WGE GY R RN GN CGIA+ Sbjct: 264 FYDQTCNQSDLNHGVLVVGYGSDNGQDYWILKNSWGSGWGESGYWRQVRNYGNNCGIATA 323 Query: 317 ASLPMV 322 AS P + Sbjct: 324 ASYPAL 329 >3QJ3-A nrPDB Length = 331 Score = 368 bits (945), Expect = e-102, Method: Composition-based stats. Identities = 128/315 (40%), Positives = 184/315 (58%), Gaps = 14/315 (4%) Query: 19 DLWHQWKRMYNKEY-NGADDQHRRNIWEKNVKHIQEHNLRHDLGLVTYTLGLNQFTDMTF 77 + W +K Y + Y N ++ R+ I++K ++ +EHN ++ GLV+YTLG+N FTDMT Sbjct: 20 EKWENFKTTYARSYVNAKEETFRKQIFQKKLETFEEHNEKYRQGLVSYTLGVNLFTDMTP 79 Query: 78 EEFKAKYLTEMSRASDILSHGVPYEAN-------NRAVPDKIDWRESGYVTEVKDQGNCG 130 EE KA Y + +D+ +G+P + + P DWR+ G V+ VK+QG+CG Sbjct: 80 EEMKA-YTHGLIMPADLHKNGIPIKTREDLGLNASVRYPASFDWRDQGMVSPVKNQGSCG 138 Query: 131 SCWAFSTTGTMEGQYMKNERT--SISFSEQQLVDCSGPWGNNGCSGGLMENAYQYL-KQF 187 S WAFS+TG +E Q S SEQQLVDC GCSGG M +A+ Y+ + Sbjct: 139 SSWAFSSTGAIESQMKIANGAGYDSSVSEQQLVDCVP--NALGCSGGWMNDAFTYVAQNG 196 Query: 188 GLETESSYPYTAVEGQCRYNKQLGVAKVTGYYTVHSGSEVELKNLVGARRPAAVAVDVES 247 G+++E +YPY +G C Y+ A+++GY + E L ++V + P AVA D + Sbjct: 197 GIDSEGAYPYEMADGNCHYDPNQVAARLSGYVYLSGPDENMLADMVATKGPVAVAFDADD 256 Query: 248 DFMMYRSGIYQSQTCSPLRVNHAVLAVGYGTQGGTDYWIVKNSWGTYWGERGYIRMARNR 307 F Y G+Y + TC + HAVL VGYG + G DYW+VKNSWG WG GY ++ARN Sbjct: 257 PFGSYSGGVYYNPTCETNKFTHAVLIVGYGNENGQDYWLVKNSWGDGWGLDGYFKIARNA 316 Query: 308 GNMCGIASLASLPMV 322 N CGIA +AS+P + Sbjct: 317 NNHCGIAGVASVPTL 331 >6CZS-A nrPDB Length = 335 Score = 359 bits (921), Expect = e-99, Method: Composition-based stats. Identities = 126/320 (39%), Positives = 172/320 (53%), Gaps = 15/320 (4%) Query: 7 AVLTVGVLGSNDDLWHQWKRMYNKEYNGADDQHRRNIWEKNVKHIQEHNLRHDLGLVTYT 66 A L V L + W + K Y+ + HR + N + I HN G T+ Sbjct: 23 AELCVNSL--EKFHFKSWMSKHRKTYSTEEYHHRLQTFASNWRKINAHNN----GNHTFK 76 Query: 67 LGLNQFTDMTFEEFKAKYL-TEMSRASDILSHGVPYEANNRAVPDKIDWRESG-YVTEVK 124 + LNQF+DM+F E K KYL +E S S+ Y P +DWR+ G +V+ VK Sbjct: 77 MALNQFSDMSFAEIKHKYLWSEPQNCSATKSN---YLRGTGPYPPSVDWRKKGNFVSPVK 133 Query: 125 DQGNCGSCWAFSTTGTMEGQYMKNERTSISFSEQQLVDCSGPWGNNGCSGGLMENAYQYL 184 +QG CGS W FSTTG +E +S +EQQLVDC+ + N+GC GGL A++Y+ Sbjct: 134 NQGACGSSWTFSTTGALESAIAIATGKMLSLAEQQLVDCAQDFNNHGCQGGLPSQAFEYI 193 Query: 185 -KQFGLETESSYPYTAVEGQCRYNKQLGVAKVTGYYTVHSGSEVELKNLVGARRPAAVAV 243 G+ E +YPY +G C++ + V + E + V P + A Sbjct: 194 LYNKGIMGEDTYPYQGKDGYCKFQPGKAIGFVKDVANITIYDEEAMVEAVALYNPVSFAF 253 Query: 244 DVESDFMMYRSGIYQSQTC--SPLRVNHAVLAVGYGTQGGTDYWIVKNSWGTYWGERGYI 301 +V DFMMYR+GIY S +C +P +VNHAVLAVGYG + G YWIVKNSWG WG GY Sbjct: 254 EVTQDFMMYRTGIYSSTSCHKTPDKVNHAVLAVGYGEKNGIPYWIVKNSWGPQWGMNGYF 313 Query: 302 RMARNRGNMCGIASLASLPM 321 + R + NMCG+A+ AS P+ Sbjct: 314 LIERGK-NMCGLAACASYPI 332 >4QRX-A nrPDB Length = 363 Score = 349 bits (896), Expect = 9e-97, Method: Composition-based stats. Identities = 111/313 (35%), Positives = 172/313 (54%), Gaps = 21/313 (6%) Query: 19 DLWHQWKRMYNKEYNGADDQ-HRRNIWEKNVKHIQEHNLRHDLGLVTYTLGLNQFTDMTF 77 L+ W +NK Y D++ +R I++ N+K+I E N +++ +Y LGLN F DM+ Sbjct: 64 QLFESWMLKHNKIYKNIDEKIYRFEIFKDNLKYIDETNKKNN----SYWLGLNVFADMSN 119 Query: 78 EEFKAKYLTEMS--RASDILSHGVPYEANNRAVPDKIDWRESGYVTEVKDQGNCGSCWAF 135 +EFK KY ++ + LS+ + +P+ +DWR+ G VT VK+QG+CGS WAF Sbjct: 120 DEFKEKYTGSIAGNYTTTELSYEEVLNDGDVNIPEYVDWRQKGAVTPVKNQGSCGSAWAF 179 Query: 136 STTGTMEGQYMKNERTSISFSEQQLVDCSGPWGNNGCSGGLMENAYQYLKQFGLETESSY 195 S T+E +SEQ+L+DC + GC+GG +A Q + Q+G+ ++Y Sbjct: 180 SAVSTIESIIKIRTGNLNEYSEQELLDCDRR--SYGCNGGYPWSALQLVAQYGIHYRNTY 237 Query: 196 PYTAVEGQCRYNKQLGV-AKVTGYYTVHSGSEVELKNLVGARRPAAVAVDVES-DFMMYR 253 PY V+ CR ++ AK G V +E L + A +P +V ++ DF +YR Sbjct: 238 PYEGVQRYCRSREKGPYAAKTDGVRQVQPYNEGALLYSI-ANQPVSVVLEAAGKDFQLYR 296 Query: 254 SGIYQSQTCSPLRVNHAVLAVGYGTQGGTDYWIVKNSWGTYWGERGYIRMARNRGNM--- 310 GI+ + +V+HAV AVGYG +Y +++NSWGT WGE GYIR+ R GN Sbjct: 297 GGIFVGPCGN--KVDHAVAAVGYG----PNYILIRNSWGTGWGENGYIRIKRGTGNSYGV 350 Query: 311 CGIASLASLPMVA 323 CG+ + + P+ Sbjct: 351 CGLYTSSFYPVKN 363 >5EF4-A nrPDB Length = 385 Score = 342 bits (877), Expect = 1e-94, Method: Composition-based stats. Identities = 114/320 (35%), Positives = 153/320 (47%), Gaps = 28/320 (8%) Query: 20 LWHQWKRMYNKEYNGADDQHRRNIWEKNVKHIQEHNLRHDLGLVTYTLGLNQFTDMTFEE 79 ++ +W+ +N E + R N+++ NV+ I E N Y L +N+F DMT E Sbjct: 38 MYDRWREQHNIEMRSPE---RFNVFKYNVRRIHESNKMDK----PYKLKVNEFADMTNLE 90 Query: 80 FKAKYLTEMSRASDILSHGVPYE-----------ANNRAVPDKIDWRESGYVTEVKDQGN 128 F Y L P AN +PDK+DWRE VT+VK QG Sbjct: 91 FVNTYANSKISHFQALRGSAPGSIDTDPNKDFIYANVTKIPDKVDWREKNAVTDVKGQGG 150 Query: 129 CGSCWAFSTTGTMEGQYMKNERTSISFSEQQLVDCSGPWGNNGCSGGLMENAYQY-LKQF 187 CGSCWAF+ +EG + FSEQQLVDC N GC GGLME A+ Y +K Sbjct: 151 CGSCWAFAAVVALEGINAIRTGKLVKFSEQQLVDCD--MTNAGCDGGLMEPAFTYVIKHG 208 Query: 188 GLETESSYPYTAVEGQCRYNKQLGVAKVTGYYTVHSGSEVELKNLVGARRPAAVAVDVES 247 G+ E+SYPY C K V K+ G V E L+ V A +P A + + Sbjct: 209 GIAPEASYPYVGKRETCDKAKIKDVLKIDGRQNVPGLDEEALRKAV-AHQPVATGIQLSG 267 Query: 248 D-FMMYRSGIYQSQTCSPLRVNHAVLAVGYG-TQGGTDYWIVKNSWGTYWGERGYIRMAR 305 Y G+Y + NH V VGYG + G +W VKNSWG WGE+GYI + R Sbjct: 268 HGLQFYSEGVYTGDCGTE--PNHGVGIVGYGENEKGIKFWTVKNSWGPTWGEKGYIHLQR 325 Query: 306 N--RGNMCGIASLASLPMVA 323 + +CG+A +S P++ Sbjct: 326 GARKEGLCGVAMHSSFPIMN 345 >1PCI-A nrPDB Length = 322 Score = 341 bits (876), Expect = 2e-94, Method: Composition-based stats. Identities = 113/312 (36%), Positives = 175/312 (56%), Gaps = 16/312 (5%) Query: 19 DLWHQWKRMYNKEYNGADDQ-HRRNIWEKNVKHIQEHNLRHDLGLVTYTLGLNQFTDMTF 77 L++ W +NK Y D++ +R I++ N+ +I E N +++ +Y LGLN+F D++ Sbjct: 20 QLFNSWMLNHNKFYENVDEKLYRFEIFKDNLNYIDETNKKNN----SYWLGLNEFADLSN 75 Query: 78 EEFKAKYLTEMSRASDILSH-GVPYEANNRAVPDKIDWRESGYVTEVKDQGNCGSCWAFS 136 +EF KY+ + A+ S+ + +P+ +DWR+ G VT V+ QG+CGSCWAFS Sbjct: 76 DEFNEKYVGSLIDATIEQSYDEEFINEDIVNLPENVDWRKKGAVTPVRHQGSCGSCWAFS 135 Query: 137 TTGTMEGQYMKNERTSISFSEQQLVDCSGPWGNNGCSGGLMENAYQYLKQFGLETESSYP 196 T+EG + SEQ+LVDC ++GC GG A +Y+ + G+ S YP Sbjct: 136 AVATVEGINKIRTGKLVELSEQELVDCERR--SHGCKGGYPPYALEYVAKNGIHLRSKYP 193 Query: 197 YTAVEGQCRYNKQLG-VAKVTGYYTVHSGSEVELKNLVGARRPAAVAVDVES-DFMMYRS 254 Y A +G CR + G + K +G V +E L N + A++P +V V+ + F +Y+ Sbjct: 194 YKAKQGTCRAKQVGGPIVKTSGVGRVQPNNEGNLLNAI-AKQPVSVVVESKGRPFQLYKG 252 Query: 255 GIYQSQTCSPLRVNHAVLAVGYGTQGGTDYWIVKNSWGTYWGERGYIRMARNRGNM---C 311 GI++ + +V+ AV AVGYG GG Y ++KNSWGT WGE+GYIR+ R GN C Sbjct: 253 GIFEGPCGT--KVDGAVTAVGYGKSGGKGYILIKNSWGTAWGEKGYIRIKRAPGNSPGVC 310 Query: 312 GIASLASLPMVA 323 G+ + P Sbjct: 311 GLYKSSYYPTKN 322 >3HWN-A nrPDB Length = 258 Score = 340 bits (871), Expect = 7e-94, Method: Composition-based stats. Identities = 122/264 (46%), Positives = 154/264 (58%), Gaps = 15/264 (5%) Query: 68 GLNQFTDMTFEEFKA---KYLTEMSRASDILSHGVPYEANNRAVPDKIDWRESGYVTEVK 124 +N F DMT EEF+ + R + + YEA P +DWRE GYVT VK Sbjct: 1 AMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEA-----PRSVDWREKGYVTPVK 55 Query: 125 DQGNCGSCWAFSTTGTMEGQYMKNERTSISFSEQQLVDCSGPWGNNGCSGGLMENAYQYL 184 +QG CGSCWAFS TG +EGQ + IS SEQ LVDCSGP GN GC+GGLM+ A+QY+ Sbjct: 56 NQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYV 115 Query: 185 K-QFGLETESSYPYTAVEGQCRYNKQLGVAKVTGYYTVHSGSEVELKNLVGARRPAAVAV 243 + GL++E SYPY A E C+YN + VA G+ + E L V P +VA+ Sbjct: 116 QDNGGLDSEESYPYEATEESCKYNPKYSVANDAGFVDIPK-QEKALMKAVATVGPISVAI 174 Query: 244 DV-ESDFMMYRSGIYQSQTCSPLRVNHAVLAVGYGTQ----GGTDYWIVKNSWGTYWGER 298 D F+ Y+ GIY CS ++H VL VGYG + YW+VKNSWG WG Sbjct: 175 DAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMG 234 Query: 299 GYIRMARNRGNMCGIASLASLPMV 322 GY++MA++R N CGIAS AS P V Sbjct: 235 GYVKMAKDRRNHCGIASAASYPTV 258 >3OF9-A nrPDB Length = 221 Score = 315 bits (806), Expect = 2e-86, Method: Composition-based stats. Identities = 111/222 (50%), Positives = 138/222 (62%), Gaps = 7/222 (3%) Query: 107 AVPDKIDWRESGYVTEVKDQGNCGSCWAFSTTGTMEGQYMKNERTSISFSEQQLVDCSGP 166 P +DWRE GYVT VK+QG CGSCWAFS TG +EGQ + IS SEQ LVDCSGP Sbjct: 1 EAPRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGP 60 Query: 167 WGNNGCSGGLMENAYQYLK-QFGLETESSYPYTAVEGQCRYNKQLGVAKVTGYYTVHSGS 225 GN GC+GGLM+ A+QY++ GL++E SYPY A E C+YN + VA TG+ + Sbjct: 61 QGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPK-Q 119 Query: 226 EVELKNLVGARRPAAVAVDV-ESDFMMYRSGIYQSQTCSPLRVNHAVLAVGYGTQ----G 280 E L V P +VA+D F+ Y+ GIY CS ++H VL VGYG + Sbjct: 120 EKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESD 179 Query: 281 GTDYWIVKNSWGTYWGERGYIRMARNRGNMCGIASLASLPMV 322 YW+VKNSWG WG GY++MA++R N CGIAS AS P V Sbjct: 180 NNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV 221 >3KFQ-A nrPDB Length = 221 Score = 313 bits (802), Expect = 7e-86, Method: Composition-based stats. Identities = 107/221 (48%), Positives = 139/221 (62%), Gaps = 6/221 (2%) Query: 108 VPDKIDWRESGYVTEVKDQGNCGSCWAFSTTGTMEGQYMKNERTSISFSEQQLVDCSGPW 167 +P +DWR+ GYVT VK+Q CGSCWAFS TG +EGQ + +S SEQ LVDCS P Sbjct: 1 LPKSVDWRKKGYVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQ 60 Query: 168 GNNGCSGGLMENAYQYLK-QFGLETESSYPYTAVEGQCRYNKQLGVAKVTGYYTVHSGSE 226 GN GC+GG M A+QY+K GL++E SYPY AV+ C+Y + VA+ TG+ V G E Sbjct: 61 GNQGCNGGFMARAFQYVKENGGLDSEESYPYVAVDEICKYRPENSVAQDTGFTVVAPGKE 120 Query: 227 VELKNLVGARRPAAVAVDV-ESDFMMYRSGIYQSQTCSPLRVNHAVLAVGYGTQ----GG 281 L V P +VA+D S F Y+SGIY CS ++H VL VGYG + Sbjct: 121 KALMKAVATVGPISVAMDAGHSSFQFYKSGIYFEPDCSSKNLDHGVLVVGYGFEGANSDN 180 Query: 282 TDYWIVKNSWGTYWGERGYIRMARNRGNMCGIASLASLPMV 322 + YW+VKNSWG WG GY+++A+++ N CGIA+ AS P V Sbjct: 181 SKYWLVKNSWGPEWGSNGYVKIAKDKNNHCGIATAASYPNV 221 >4P6E-A nrPDB Length = 230 Score = 308 bits (789), Expect = 2e-84, Method: Composition-based stats. Identities = 107/222 (48%), Positives = 141/222 (63%), Gaps = 4/222 (1%) Query: 105 NRAVPDKIDWRESGYVTEVKDQGNCGSCWAFSTTGTMEGQYMKNERTSISFSEQQLVDCS 164 NR +PD +DWRE G VTEVK QG+CG+CWAFS G +E Q +S S Q LVDCS Sbjct: 4 NRILPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCS 63 Query: 165 G-PWGNNGCSGGLMENAYQYL-KQFGLETESSYPYTAVEGQCRYNKQLGVAKVTGYYTVH 222 +GN GC+GG M A+QY+ G+++++SYPY A++ +C+Y+ + A + Y + Sbjct: 64 TEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELP 123 Query: 223 SGSEVELKNLVGARRPAAVAVDV-ESDFMMYRSGIYQSQTCSPLRVNHAVLAVGYGTQGG 281 G E LK V + P +V VD F +YRSG+Y +C+ VNH VL VGYG G Sbjct: 124 YGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQ-NVNHGVLVVGYGDLNG 182 Query: 282 TDYWIVKNSWGTYWGERGYIRMARNRGNMCGIASLASLPMVA 323 +YW+VKNSWG +GE GYIRMARN+GN CGIAS S P + Sbjct: 183 KEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIASFPSYPEIE 224 >4BS5-A nrPDB Length = 225 Score = 305 bits (780), Expect = 2e-83, Method: Composition-based stats. Identities = 110/223 (49%), Positives = 140/223 (62%), Gaps = 5/223 (2%) Query: 104 NNRAVPDKIDWRESGYVTEVKDQGNCGSCWAFSTTGTMEGQYMKNERTSISFSEQQLVDC 163 +NR +PD +DWRE G VTEVK QG+CG+CWAFS G +EGQ IS S Q LVDC Sbjct: 4 SNRTLPDTVDWREKGCVTEVKYQGSCGACWAFSAVGALEGQLKLKTGKLISLSAQNLVDC 63 Query: 164 S--GPWGNNGCSGGLMENAYQYL-KQFGLETESSYPYTAVEGQCRYNKQLGVAKVTGYYT 220 S +GN GC GG M A+QY+ G+E ++SYPY A++ +C YN + A + Y Sbjct: 64 SNEEKYGNKGCGGGYMTEAFQYIIDNGGIEADASYPYKAMDEKCHYNSKNRAATCSRYIQ 123 Query: 221 VHSGSEVELKNLVGARRPAAVAVDV-ESDFMMYRSGIYQSQTCSPLRVNHAVLAVGYGTQ 279 + G E LK V + P +V +D S F Y+SG+Y +C+ VNH VL VGYGT Sbjct: 124 LPFGDEDALKEAVATKGPVSVGIDASHSSFFFYKSGVYDDPSCTG-NVNHGVLVVGYGTL 182 Query: 280 GGTDYWIVKNSWGTYWGERGYIRMARNRGNMCGIASLASLPMV 322 G DYW+VKNSWG +G++GYIRMARN N CGIAS S P + Sbjct: 183 DGKDYWLVKNSWGLNFGDQGYIRMARNNKNHCGIASYCSYPEI 225 >5JA7-A nrPDB Length = 223 Score = 303 bits (777), Expect = 5e-83, Method: Composition-based stats. Identities = 104/217 (47%), Positives = 136/217 (62%), Gaps = 4/217 (1%) Query: 108 VPDKIDWRESGYVTEVKDQGNCGSCWAFSTTGTMEGQYMKNERTSISFSEQQLVDCSGPW 167 PD +D+R+ GYVT VK+QG CGS WAFS+ G +EGQ K ++ S Q LVDC Sbjct: 9 APDSVDYRKKGYVTPVKNQGQCGSSWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSE- 67 Query: 168 GNNGCSGGLMENAYQYLK-QFGLETESSYPYTAVEGQCRYNKQLGVAKVTGYYTVHSGSE 226 N+GC GG M NA+QY++ G+++E +YPY E C YN AK GY + G+E Sbjct: 68 -NDGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNE 126 Query: 227 VELKNLVGARRPAAVAVDVE-SDFMMYRSGIYQSQTCSPLRVNHAVLAVGYGTQGGTDYW 285 LK V P +VA+D + F Y G+Y ++C+ +NHAVLAVGYG Q G +W Sbjct: 127 KALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHW 186 Query: 286 IVKNSWGTYWGERGYIRMARNRGNMCGIASLASLPMV 322 I+KNSWG WG +GYI MARN+ N CGIA+LAS P + Sbjct: 187 IIKNSWGENWGNKGYILMARNKNNACGIANLASFPKM 223 >1S4V-A nrPDB Length = 229 Score = 301 bits (770), Expect = 3e-82, Method: Composition-based stats. Identities = 100/222 (45%), Positives = 131/222 (59%), Gaps = 11/222 (4%) Query: 108 VPDKIDWRESGYVTEVKDQGNCGSCWAFSTTGTMEGQYMKNERTSISFSEQQLVDCSGPW 167 VP +DWR+ G VT VKDQG CGSCWAFST +EG +S SEQ+LVDC Sbjct: 2 VPASVDWRKKGAVTSVKDQGQCGSCWAFSTIVAVEGINQIKTNKLVSLSEQELVDCDTDQ 61 Query: 168 GNNGCSGGLMENAYQYLKQ-FGLETESSYPYTAVEGQCRYNKQ-LGVAKVTGYYTVHSGS 225 N GC+GGLM+ A++++KQ G+ TE++YPY A +G C +K+ + G+ V Sbjct: 62 -NQGCNGGLMDYAFEFIKQRGGITTEANYPYEAYDGTCDVSKENAPAVSIDGHENVPEND 120 Query: 226 EVELKNLVGARRPAAVAVDV-ESDFMMYRSGIYQSQTCSPLRVNHAVLAVGYGTQ-GGTD 283 E L V A +P +VA+D SDF Y G++ + ++H V VGYGT GT Sbjct: 121 ENALLKAV-ANQPVSVAIDAGGSDFQFYSEGVFTGSCGTE--LDHGVAIVGYGTTIDGTK 177 Query: 284 YWIVKNSWGTYWGERGYIRMARN---RGNMCGIASLASLPMV 322 YW VKNSWG WGE+GYIRM R + +CGIA AS P+ Sbjct: 178 YWTVKNSWGPEWGEKGYIRMERGISDKEGLCGIAMEASYPIK 219 >2VHS-A nrPDB Length = 217 Score = 300 bits (768), Expect = 6e-82, Method: Composition-based stats. Identities = 109/218 (50%), Positives = 137/218 (62%), Gaps = 4/218 (1%) Query: 108 VPDKIDWRESGYVTEVKDQGNCGSCWAFSTTGTMEGQYMKNERTSISFSEQQLVDCSGPW 167 P +DWRE GYVT VK+QG CG+ +AFS TG +EGQ + IS SEQ LVDCSGP Sbjct: 1 APRSVDWREKGYVTPVKNQGQCGASYAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQ 60 Query: 168 GNNGCSGGLMENAYQYLK-QFGLETESSYPYTAVEGQCRYNKQLGVAKVTGYYTVHSGSE 226 GN GC+GGLM+ A+QY++ GL++E SYPY A E C+YN + VA G+ + E Sbjct: 61 GNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDVGFVDIPK-QE 119 Query: 227 VELKNLVGARRPAAVAVDV-ESDFMMYRSGIYQSQTCSPLRVNHAVLAVGYG-TQGGTDY 284 L V P +VA+D F+ Y+ GIY S CS +NHA+L VGYG Y Sbjct: 120 KALMKAVATVGPISVAIDAGHESFLFYKEGIYFSSDCSSSSLNHAMLVVGYGFISNNQKY 179 Query: 285 WIVKNSWGTYWGERGYIRMARNRGNMCGIASLASLPMV 322 W+VKNSWG WG GY++MA++R N CGIAS AS P V Sbjct: 180 WLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV 217 >6BKI-A nrPDB Length = 215 Score = 296 bits (759), Expect = 6e-81, Method: Composition-based stats. Identities = 101/217 (46%), Positives = 133/217 (61%), Gaps = 4/217 (1%) Query: 108 VPDKIDWRESGYVTEVKDQGNCGSCWAFSTTGTMEGQYMKNERTSISFSEQQLVDCSGPW 167 VPD ID+R+ GYVT VK+QG CGSCWAFS+ G +EGQ K ++ S Q LVDC Sbjct: 1 VPDSIDYRKKGYVTPVKNQGQCGSCWAFSSAGALEGQLKKKTGKLLALSPQNLVDCVTE- 59 Query: 168 GNNGCSGGLMENAYQYLK-QFGLETESSYPYTAVEGQCRYNKQLGVAKVTGYYTVHSGSE 226 N GC GG M A+QY++ G+++E +YPY + C YN AK GY + G+E Sbjct: 60 -NYGCGGGYMTTAFQYVQQNGGIDSEDAYPYVGQDESCMYNAAAKAAKCRGYREIPVGNE 118 Query: 227 VELKNLVGARRPAAVAVDVE-SDFMMYRSGIYQSQTCSPLRVNHAVLAVGYGTQGGTDYW 285 LK V P +V++D + F Y G+Y + C VNHAVL VGYGTQ G+ +W Sbjct: 119 KALKRAVARVGPISVSIDASLASFQFYSRGVYYDENCDRDNVNHAVLVVGYGTQKGSKHW 178 Query: 286 IVKNSWGTYWGERGYIRMARNRGNMCGIASLASLPMV 322 I+KNSWG WG +GY +ARN+ N CGI ++AS P + Sbjct: 179 IIKNSWGESWGNKGYALLARNKNNACGITNMASFPKM 215 >3P5W-A nrPDB Length = 220 Score = 295 bits (755), Expect = 2e-80, Method: Composition-based stats. Identities = 103/220 (46%), Positives = 133/220 (60%), Gaps = 8/220 (3%) Query: 108 VPDKIDWRESGYVTEVKDQGNCGSCWAFSTTGTMEGQYMKNERTSISFSEQQLVDCSGPW 167 +PD +DWR SG V ++KDQG CGSCWAFST +EG IS SEQ+LVDC Sbjct: 1 LPDYVDWRSSGAVVDIKDQGQCGSCWAFSTIAAVEGINKIATGDLISLSEQELVDCGRTQ 60 Query: 168 GNNGCSGGLMENAYQY-LKQFGLETESSYPYTAVEGQCRYN-KQLGVAKVTGYYTVHSGS 225 GC GG M + +Q+ + G+ TE++YPYTA EGQC + +Q + Y V + Sbjct: 61 NTRGCDGGFMTDGFQFIINNGGINTEANYPYTAEEGQCNLDLQQEKYVSIDTYENVPYNN 120 Query: 226 EVELKNLVGARRPAAVAVDVES-DFMMYRSGIYQSQTCSPLRVNHAVLAVGYGTQGGTDY 284 E L+ V A +P +VA++ +F Y SGI+ + V+HAV VGYGT+GG DY Sbjct: 121 EWALQTAV-AYQPVSVALEAAGYNFQHYSSGIFTGPCGT--AVDHAVTIVGYGTEGGIDY 177 Query: 285 WIVKNSWGTYWGERGYIRMARNRG--NMCGIASLASLPMV 322 WIVKNSWGT WGE GY+R+ RN G CGIA AS P+ Sbjct: 178 WIVKNSWGTTWGEEGYMRIQRNVGGVGQCGIAKKASYPVK 217 >2FO5-A nrPDB Length = 262 Score = 292 bits (748), Expect = 1e-79, Method: Composition-based stats. Identities = 97/225 (43%), Positives = 133/225 (59%), Gaps = 14/225 (6%) Query: 108 VPDKIDWRESGYVTEVKDQGNCGSCWAFSTTGTMEGQYMKNERTSISFSEQQLVDCSGPW 167 +P +DWR+ G VT VKDQG CGSCWAFST ++EG + +S SEQ+L+DC Sbjct: 4 LPPSVDWRQKGAVTGVKDQGKCGSCWAFSTVVSVEGINAIRTGSLVSLSEQELIDCDTA- 62 Query: 168 GNNGCSGGLMENAYQYLK-QFGLETESSYPYTAVEGQCR----YNKQLGVAKVTGYYTVH 222 N+GC GGLM+NA++Y+K GL TE++YPY A G C V + G+ V Sbjct: 63 DNDGCQGGLMDNAFEYIKNNGGLITEAAYPYRAARGTCNVARAAQNSPVVVHIDGHQDVP 122 Query: 223 SGSEVELKNLVGARRPAAVAVDVES-DFMMYRSGIYQSQTCSPLRVNHAVLAVGYGT-QG 280 + SE +L V A +P +VAV+ FM Y G++ + + ++H V VGYG + Sbjct: 123 ANSEEDLARAV-ANQPVSVAVEASGKAFMFYSEGVFTGECGTE--LDHGVAVVGYGVAED 179 Query: 281 GTDYWIVKNSWGTYWGERGYIRMARN---RGNMCGIASLASLPMV 322 G YW VKNSWG WGE+GYIR+ ++ G +CGIA AS P+ Sbjct: 180 GKAYWTVKNSWGPSWGEQGYIRVEKDSGASGGLCGIAMEASYPVK 224 >1CQD-A nrPDB Length = 221 Score = 291 bits (746), Expect = 2e-79, Method: Composition-based stats. Identities = 100/220 (45%), Positives = 126/220 (57%), Gaps = 10/220 (4%) Query: 108 VPDKIDWRESGYVTEVKDQGNCGSCWAFSTTGTMEGQYMKNERTSISFSEQQLVDCSGPW 167 +PD IDWRE+G V VK+QG CGSCWAFST +EG IS SEQQLVDC+ Sbjct: 3 LPDSIDWRENGAVVPVKNQGGCGSCWAFSTVAAVEGINQIVTGDLISLSEQQLVDCTTA- 61 Query: 168 GNNGCSGGLMENAYQYL-KQFGLETESSYPYTAVEGQCRYNKQLGVAKVTGYYTVHSGSE 226 N+GC GG M A+Q++ G+ +E +YPY +G C V + Y V S +E Sbjct: 62 -NHGCRGGWMNPAFQFIVNNGGINSEETYPYRGQDGICNSTVNAPVVSIDSYENVPSHNE 120 Query: 227 VELKNLVGARRPAAVAVDVES-DFMMYRSGIYQSQTCSPLRVNHAVLAVGYGTQGGTDYW 285 L+ V A +P +V +D DF +YRSGI+ + NHA+ VGYGT+ D+W Sbjct: 121 QSLQKAV-ANQPVSVTMDAAGRDFQLYRSGIFTGSC--NISANHALTVVGYGTENDKDFW 177 Query: 286 IVKNSWGTYWGERGYIRMARNRGN---MCGIASLASLPMV 322 IVKNSWG WGE GYIR RN N CGI AS P+ Sbjct: 178 IVKNSWGKNWGESGYIRAERNIENPDGKCGITRFASYPVK 217 >1NB3-A nrPDB Length = 220 Score = 291 bits (746), Expect = 2e-79, Method: Composition-based stats. Identities = 95/217 (43%), Positives = 132/217 (60%), Gaps = 5/217 (2%) Query: 109 PDKIDWRESG-YVTEVKDQGNCGSCWAFSTTGTMEGQYMKNERTSISFSEQQLVDCSGPW 167 P +DWR+ G +V+ VK+QG+CGSCW FSTTG +E +S +EQQLVDC+ + Sbjct: 2 PPSMDWRKKGNFVSPVKNQGSCGSCWTFSTTGALESAVAIATGKMLSLAEQQLVDCAQNF 61 Query: 168 GNNGCSGGLMENAYQYLK-QFGLETESSYPYTAVEGQCRYNKQLGVAKVTGYYTVHSGSE 226 N+GC GGL A++Y++ G+ E +YPY + C++ +A V + E Sbjct: 62 NNHGCQGGLPSQAFEYIRYNKGIMGEDTYPYKGQDDHCKFQPDKAIAFVKDVANITMNDE 121 Query: 227 VELKNLVGARRPAAVAVDVESDFMMYRSGIYQSQTC--SPLRVNHAVLAVGYGTQGGTDY 284 + V P + A +V +DF+MYR GIY S +C +P +VNHAVLAVGYG + G Y Sbjct: 122 EAMVEAVALYNPVSFAFEVTNDFLMYRKGIYSSTSCHKTPDKVNHAVLAVGYGEENGIPY 181 Query: 285 WIVKNSWGTYWGERGYIRMARNRGNMCGIASLASLPM 321 WIVKNSWG WG GY + R + NMCG+A+ AS P+ Sbjct: 182 WIVKNSWGPQWGMNGYFLIERGK-NMCGLAACASYPI 217 >1AEC-A nrPDB Length = 218 Score = 288 bits (736), Expect = 3e-78, Method: Composition-based stats. Identities = 92/220 (41%), Positives = 128/220 (58%), Gaps = 8/220 (3%) Query: 108 VPDKIDWRESGYVTEVKDQGNCGSCWAFSTTGTMEGQYMKNERTSISFSEQQLVDCSGPW 167 +P +DWR +G V ++K QG CG CWAFS T+EG IS SEQ+L+DC Sbjct: 1 LPSYVDWRSAGAVVDIKSQGECGGCWAFSAIATVEGINKIVTGVLISLSEQELIDCGRTQ 60 Query: 168 GNNGCSGGLMENAYQY-LKQFGLETESSYPYTAVEGQCRYN-KQLGVAKVTGYYTVHSGS 225 GC+GG + + +Q+ + G+ TE +YPYTA +G+C + + + Y V + Sbjct: 61 NTRGCNGGYITDGFQFIINNGGINTEENYPYTAQDGECNVDLQNEKYVTIDTYENVPYNN 120 Query: 226 EVELKNLVGARRPAAVAVDVESD-FMMYRSGIYQSQTCSPLRVNHAVLAVGYGTQGGTDY 284 E L+ V +P +VA+D D F Y SGI+ + ++HAV VGYGT+GG DY Sbjct: 121 EWALQTAV-TYQPVSVALDAAGDAFKQYSSGIFTGPCGT--AIDHAVTIVGYGTEGGIDY 177 Query: 285 WIVKNSWGTYWGERGYIRMARNRG--NMCGIASLASLPMV 322 WIVKNSW T WGE GY+R+ RN G CGIA++ S P+ Sbjct: 178 WIVKNSWDTTWGEEGYMRILRNVGGAGTCGIATMPSYPVK 217 >3PDF-A nrPDB Length = 441 Score = 288 bits (736), Expect = 3e-78, Method: Composition-based stats. Identities = 99/308 (32%), Positives = 146/308 (47%), Gaps = 37/308 (12%) Query: 39 HRRNIWEK--NVKHIQEHNLRHDLGLVTYTLGLNQFTDMTFEEFKAKYLTEMSRASDILS 96 H +N EK N + +HN + + +T T+ E++ L +M R S S Sbjct: 131 HLKNSQEKYSNRLYKYDHNFVKAINAIQ-----KSWTATTYMEYETLTLGDMIRRSGGHS 185 Query: 97 HGVP----------YEANNRAVPDKIDWRES---GYVTEVKDQGNCGSCWAFSTTGTMEG 143 +P + +P DWR +V+ V++Q +CGSC++F++ G +E Sbjct: 186 RKIPRPKPAPLTAEIQQKILFLPTSWDWRNVHGINFVSPVRNQASCGSCYSFASMGMLEA 245 Query: 144 QYMK--NERTSISFSEQQLVDCSGPWGNNGCSGGLME-NAYQYLKQFGLETESSYPYTAV 200 + N + S Q++V CS GC GG A +Y + FGL E+ +PYT Sbjct: 246 RIRILTNNSQTPILSPQEVVSCS--QYAQGCEGGFPYLIAGKYAQDFGLVEEACFPYTGT 303 Query: 201 EGQCRYNKQLGVAKVTGYYTVHS----GSEVELKNLVGARRPAAVAVDVESDFMMYRSGI 256 + C+ + + Y+ V +E +K + P AVA +V DF+ Y+ GI Sbjct: 304 DSPCKMKEDCFRYYSSEYHYVGGFYGGCNEALMKLELVHHGPMAVAFEVYDDFLHYKKGI 363 Query: 257 YQS----QTCSPLRV-NHAVLAVGYGTQG--GTDYWIVKNSWGTYWGERGYIRMARNRGN 309 Y +P + NHAVL VGYGT G DYWIVKNSWGT WGE GY R+ R + Sbjct: 364 YHHTGLRDPFNPFELTNHAVLLVGYGTDSASGMDYWIVKNSWGTGWGENGYFRIRRGT-D 422 Query: 310 MCGIASLA 317 C I S+A Sbjct: 423 ECAIESIA 430 >5JT8-A nrPDB Length = 333 Score = 286 bits (733), Expect = 7e-78, Method: Composition-based stats. Identities = 95/339 (28%), Positives = 167/339 (49%), Gaps = 23/339 (6%) Query: 1 MRLFILAVLTVGV-LGSND------DLWHQWKRMYNKEYNGADDQHRR-NIWEKNVKHIQ 52 M+ ++A L V +GS + Q+K+++ K Y A+++ RR + +++ +K ++ Sbjct: 1 MKFLLVAALCALVAIGSCKPTREEIKTFEQFKKVFGKVYRNAEEEARREHHFKEQLKWVE 60 Query: 53 EHNLRHDLGLVTYTLGLNQFTDMTFEEFKAKYLTEMSRAS--DILSHGVPYEANNRAVPD 110 EHN G+ +N+++DM+ +EF + + + P ++P Sbjct: 61 EHN-----GIDGVEYAINEYSDMSEQEFSFHLSGGGLNFTYMKMEAAKEPLINTYGSLPQ 115 Query: 111 KIDWRESGYVTEVKDQGNCGSCWAFSTTGTMEGQYMKNERTSISFSEQQLVDC-----SG 165 DWR+ +T ++ QG+CGSCWAF+ G E Y ++ SI SEQ+LVDC Sbjct: 116 NFDWRQKARLTRIRQQGSCGSCWAFAAAGVAESLYSIQKQQSIELSEQELVDCTYNRYDP 175 Query: 166 PWGNNGCSGGLMENAYQYLKQFGLETESSYPYTAVEGQCRYNKQLGVAKVTGYYTV-HSG 224 + NGC G A++Y+ + GL E +YPY C + + V+GY + + Sbjct: 176 SYQCNGCGSGYSTEAFKYMIRTGLVEERNYPYNMRTQWCDPDVEGQRYHVSGYQQLRYHS 235 Query: 225 SEVELKNLVGARRPAAVAVDVESD-FMMYRSGIYQSQTCSPLRVNHAVLAVGYGTQGGTD 283 S+ ++ + P + + ++ F +G+ + + +HAV+ VG+GT G D Sbjct: 236 SDEDVMYTIQQHGPVVIYMHGSNNYFRNLGNGVLRGVAYNDAYTDHAVILVGWGTVQGVD 295 Query: 284 YWIVKNSWGTYWGERGYIRMARNRGNMCGIASLASLPMV 322 YWI++NSWGT WG GY + R N GI + + + Sbjct: 296 YWIIRNSWGTGWGNGGYGYVERG-HNSLGINNYVTYATL 333 >4YYR-A nrPDB Length = 222 Score = 285 bits (730), Expect = 2e-77, Method: Composition-based stats. Identities = 93/221 (42%), Positives = 135/221 (61%), Gaps = 9/221 (4%) Query: 108 VPDKIDWRESGYVTEVKDQGNCGSCWAFSTTGTMEGQYMKNERTSISFSEQQLVDCSGPW 167 +P+ +DWR G V +++QG CGSCWAFS +EG S SEQQLVDC+ + Sbjct: 1 LPETVDWRIQGAVNPIRNQGRCGSCWAFSVVVVVEGITKIVTDELPSLSEQQLVDCATSY 60 Query: 168 GNNGCSGGLMENAYQY-LKQFGLETESSYPYTAVEGQCRYN-KQLGVAKVTGYYTVHSGS 225 N GCSGG M AY Y +K G+ ++S+YPYTA +G+C + VA + Y V + Sbjct: 61 KNLGCSGGWMTKAYDYIIKNGGITSQSNYPYTAKKGECNKDLASQIVATIDSYEHVPRNN 120 Query: 226 EVELKNLVGARRPAAVAVDVES-DFMMYRSGIYQSQTCSPLRVNHAVLAVGYGTQGGTDY 284 E LKN V A +P +V ++ F +Y+SG++ + +++HAV+A+GYG++ DY Sbjct: 121 ENALKNAV-ANQPVSVTIEAGGRAFELYKSGVFVGSCGT--KLDHAVVAIGYGSENDVDY 177 Query: 285 WIVKNSWGTYWGERGYIRMARNRG---NMCGIASLASLPMV 322 W+V+NSWGT WGERGYI++ RN CGIA ++ P+ Sbjct: 178 WLVRNSWGTNWGERGYIKLQRNVAEPTGKCGIAMQSTYPVK 218 >1IWD-A nrPDB Length = 215 Score = 284 bits (727), Expect = 4e-77, Method: Composition-based stats. Identities = 94/221 (42%), Positives = 128/221 (57%), Gaps = 11/221 (4%) Query: 108 VPDKIDWRESGYVTEVKDQGNCGSCWAFSTTGTMEGQYMKNERTSISFSEQQLVDCSGPW 167 +P +DWR G V +K+Q CGSCWAFS +E IS SEQ+LVDC Sbjct: 1 LPSFVDWRSKGAVNSIKNQKQCGSCWAFSAVAAVESINKIRTGQLISLSEQELVDCDTA- 59 Query: 168 GNNGCSGGLMENAYQY-LKQFGLETESSYPYTAVEGQCRYNKQLGVAKVTGYYTVHSGSE 226 ++GC+GG M NA+QY + G++T+ +YPY+AV+G C+ + L V + G+ V +E Sbjct: 60 -SHGCNGGWMNNAFQYIITNGGIDTQQNYPYSAVQGSCKPYR-LRVVSINGFQRVTRNNE 117 Query: 227 VELKNLVGARRPAAVAVDVES-DFMMYRSGIYQSQTCSPLRVNHAVLAVGYGTQGGTDYW 285 L++ V A +P +V V+ F Y SGI+ + NH V+ VGYGTQ G +YW Sbjct: 118 SALQSAV-ASQPVSVTVEAAGAPFQHYSSGIFTGPCGTAQ--NHGVVIVGYGTQSGKNYW 174 Query: 286 IVKNSWGTYWGERGYIRMARN---RGNMCGIASLASLPMVA 323 IV+NSWG WG +GYI M RN +CGIA L S P A Sbjct: 175 IVRNSWGQNWGNQGYIWMERNVASSAGLCGIAQLPSYPTKA 215 >4YYW-A nrPDB Length = 220 Score = 283 bits (724), Expect = 8e-77, Method: Composition-based stats. Identities = 93/222 (41%), Positives = 131/222 (59%), Gaps = 9/222 (4%) Query: 108 VPDKIDWRESGYVTEVKDQGNCGSCWAFSTTGTMEGQYMKNERTSISFSEQQLVDCSGPW 167 +P+ +DWR G V ++DQG CGSCW FS T +EG T S SEQ+L+DC+ + Sbjct: 1 LPETVDWRSKGAVDPIRDQGKCGSCWVFSVTVVVEGIVKIVTDTLPSLSEQELLDCAPSY 60 Query: 168 GNNGCSGGLMENAYQY-LKQFGLETESSYPYTAVEGQCRYNK-QLGVAKVTGYYTVHSGS 225 + GC GG M+ AY Y +K G+ +ES YPYTA +G C K VA ++ Y V + + Sbjct: 61 KDLGCKGGWMDKAYDYIIKDRGITSESDYPYTARKGACDSRKATEVVATISSYEDVPADN 120 Query: 226 EVELKNLVGARRPAAVAVDVES-DFMMYRSGIYQSQTCSPLRVNHAVLAVGYGTQGGTDY 284 E LK V A +P +VA+D S Y SG++ +HAV+ VGYGT+ G +Y Sbjct: 121 EDALKKAV-ANQPVSVAIDASSAAVKEYSSGVFVGSCGVAN--DHAVVVVGYGTESGVNY 177 Query: 285 WIVKNSWGTYWGERGYIRMARNR---GNMCGIASLASLPMVA 323 W+V+NSWGT WGE GY+++ R+ CGIA ++ P+ A Sbjct: 178 WLVRNSWGTKWGEEGYMKLERDTAHPAGKCGIAMESTYPVKA 219 >2ACT-A nrPDB Length = 220 Score = 283 bits (724), Expect = 8e-77, Method: Composition-based stats. Identities = 92/220 (41%), Positives = 127/220 (57%), Gaps = 8/220 (3%) Query: 108 VPDKIDWRESGYVTEVKDQGNCGSCWAFSTTGTMEGQYMKNERTSISFSEQQLVDCSGPW 167 +P +DWR +G V ++K QG CG CWAFS T+EG + IS SEQ+L+DC Sbjct: 1 LPSYVDWRSAGAVVDIKSQGECGGCWAFSAIATVEGINKITSGSLISLSEQELIDCGRTQ 60 Query: 168 GNNGCSGGLMENAYQYLKQ-FGLETESSYPYTAVEGQCRYN-KQLGVAKVTGYYTVHSGS 225 GC GG + + +Q++ G+ TE +YPYTA +G C + + Y V + Sbjct: 61 NTRGCDGGYITDGFQFIINDGGINTEENYPYTAQDGDCDVALQDQKYVTIDTYENVPYNN 120 Query: 226 EVELKNLVGARRPAAVAVDVESD-FMMYRSGIYQSQTCSPLRVNHAVLAVGYGTQGGTDY 284 E L+ V +P +VA+D D F Y SGI+ + V+HA++ VGYGT+GG DY Sbjct: 121 EWALQTAV-TYQPVSVALDAAGDAFKQYASGIFTGPCGT--AVDHAIVIVGYGTEGGVDY 177 Query: 285 WIVKNSWGTYWGERGYIRMARNRG--NMCGIASLASLPMV 322 WIVKNSW T WGE GY+R+ RN G CGIA++ S P+ Sbjct: 178 WIVKNSWDTTWGEEGYMRILRNVGGAGTCGIATMPSYPVK 217 >2PNS-A nrPDB Length = 208 Score = 282 bits (722), Expect = 1e-76, Method: Composition-based stats. Identities = 106/219 (48%), Positives = 136/219 (62%), Gaps = 14/219 (6%) Query: 108 VPDKIDWRESGYVTEVKDQGNCGSCWAFSTTGTMEGQYMKNERTSISFSEQQLVDCSGPW 167 +P++IDWR+ G VT VK+QG CGSCWAFST T+E IS SEQQLVDC+ Sbjct: 1 LPEQIDWRKKGAVTPVKNQGKCGSCWAFSTVSTVESINQIRTGNLISLSEQQLVDCNKK- 59 Query: 168 GNNGCSGGLMENAYQY-LKQFGLETESSYPYTAVEGQCRYNKQLGVAKVTGYYTVHSGSE 226 N+GC GG AYQY + G++TE++YPY AV+G CR K+ V ++ GY V +E Sbjct: 60 -NHGCKGGAFVYAYQYIIDNGGIDTEANYPYKAVQGPCRAAKK--VVRIDGYKGVPHCNE 116 Query: 227 VELKNLVGARRPAAVAVDVES-DFMMYRSGIYQSQTCSPLRVNHAVLAVGYGTQGGTDYW 285 LK V A +P+ VA+D S F Y+SGI+ + ++NH V+ VGY DYW Sbjct: 117 NALKKAV-ASQPSVVAIDASSKQFQHYKSGIFSGPCGT--KLNHGVVIVGY----WKDYW 169 Query: 286 IVKNSWGTYWGERGYIRMARNRG-NMCGIASLASLPMVA 323 IV+NSWG YWGE+GYIRM R G +CGIA L P A Sbjct: 170 IVRNSWGRYWGEQGYIRMKRVGGCGLCGIARLPYYPTKA 208 >3F75-A nrPDB Length = 224 Score = 281 bits (720), Expect = 2e-76, Method: Composition-based stats. Identities = 91/222 (40%), Positives = 131/222 (59%), Gaps = 9/222 (4%) Query: 107 AVPDKIDWRESGYVTEVKDQGNCGSCWAFSTTGTMEGQYMKNERTSISFSEQQLVDCSGP 166 +P +DWR G VT VKDQ +CGSCWAFSTTG +EG + +S SEQ+L+DCS Sbjct: 6 ELPAGVDWRSRGCVTPVKDQRDCGSCWAFSTTGALEGAHCAKTGKLVSLSEQELMDCSRA 65 Query: 167 WGNNGCSGGLMENAYQYLKQ-FGLETESSYPYTAVEGQCRYNKQLGVAKVTGYYTVHSGS 225 GN CSGG M +A+QY+ G+ +E +YPY A + +CR V K+ G+ V S Sbjct: 66 EGNQSCSGGEMNDAFQYVLDSGGICSEDAYPYLARDEECRAQSCEKVVKILGFKDVPRRS 125 Query: 226 EVELKNLVGARRPAAVAVDVES-DFMMYRSGIYQSQTCSPLRVNHAVLAVGYGT--QGGT 282 E +K + A+ P ++A++ + F Y G++ + + ++H VL VGYGT + Sbjct: 126 EAAMKAAL-AKSPVSIAIEADQMPFQFYHEGVFDASCGTD--LDHGVLLVGYGTDKESKK 182 Query: 283 DYWIVKNSWGTYWGERGYIRMA--RNRGNMCGIASLASLPMV 322 D+WI+KNSWGT WG GY+ MA + CG+ AS P++ Sbjct: 183 DFWIMKNSWGTGWGRDGYMYMAMHKGEEGQCGLLLDASFPVM 224 >3BCN-A nrPDB Length = 209 Score = 281 bits (719), Expect = 3e-76, Method: Composition-based stats. Identities = 101/219 (46%), Positives = 132/219 (60%), Gaps = 14/219 (6%) Query: 108 VPDKIDWRESGYVTEVKDQGNCGSCWAFSTTGTMEGQYMKNERTSISFSEQQLVDCSGPW 167 +P+ +DWR G V +K+QG CGSCWAFST T+E IS SEQQLVDCS Sbjct: 1 LPEHVDWRAKGAVIPLKNQGKCGSCWAFSTVTTVESINQIRTGNLISLSEQQLVDCSKK- 59 Query: 168 GNNGCSGGLMENAYQY-LKQFGLETESSYPYTAVEGQCRYNKQLGVAKVTGYYTVHSGSE 226 N+GC GG + AYQY + G++TE++YPY A +G CR K+ V ++ G V +E Sbjct: 60 -NHGCKGGYFDRAYQYIIANGGIDTEANYPYKAFQGPCRAAKK--VVRIDGCKGVPQCNE 116 Query: 227 VELKNLVGARRPAAVAVDVES-DFMMYRSGIYQSQTCSPLRVNHAVLAVGYGTQGGTDYW 285 LKN V A +P+ VA+D S F Y+ GI+ + ++NH V+ VGYG DYW Sbjct: 117 NALKNAV-ASQPSVVAIDASSKQFQHYKGGIFTGPCGT--KLNHGVVIVGYG----KDYW 169 Query: 286 IVKNSWGTYWGERGYIRMARNRG-NMCGIASLASLPMVA 323 IV+NSWG +WGE+GY RM R G +CGIA L P A Sbjct: 170 IVRNSWGRHWGEQGYTRMKRVGGCGLCGIARLPFYPTKA 208 >1YAL-A nrPDB Length = 218 Score = 277 bits (709), Expect = 4e-75, Method: Composition-based stats. Identities = 90/219 (41%), Positives = 121/219 (55%), Gaps = 10/219 (4%) Query: 109 PDKIDWRESGYVTEVKDQGNCGSCWAFSTTGTMEGQYMKNERTSISFSEQQLVDCSGPWG 168 P IDWR G VT VK+QG CGSCWAFST T+EG + SEQ+LVDC Sbjct: 2 PQSIDWRAKGAVTPVKNQGACGSCWAFSTIATVEGINKIVTGNLLELSEQELVDCDK--H 59 Query: 169 NNGCSGGLMENAYQYLKQFGLETESSYPYTAVEGQCRY-NKQLGVAKVTGYYTVHSGSEV 227 + GC GG + QY+ G+ T YPY A + +CR +K K+TGY V S E Sbjct: 60 SYGCKGGYQTTSLQYVANNGVHTSKVYPYQAKQYKCRATDKPGPKVKITGYKRVPSNCET 119 Query: 228 ELKNLVGARRPAAVAVDVES-DFMMYRSGIYQSQTCSPLRVNHAVLAVGYGTQGGTDYWI 286 + A +P +V V+ F +Y+SG++ + +++HAV AVGYGT G +Y I Sbjct: 120 SFLGAL-ANQPLSVLVEAGGKPFQLYKSGVFDGPCGT--KLDHAVTAVGYGTSDGKNYII 176 Query: 287 VKNSWGTYWGERGYIRMARNRGN---MCGIASLASLPMV 322 +KNSWG WGE+GY+R+ R GN CG+ + P Sbjct: 177 IKNSWGPNWGEKGYMRLKRQSGNSQGTCGVYKSSYYPFK 215 >1O0E-A nrPDB Length = 208 Score = 276 bits (705), Expect = 1e-74, Method: Composition-based stats. Identities = 101/219 (46%), Positives = 132/219 (60%), Gaps = 14/219 (6%) Query: 108 VPDKIDWRESGYVTEVKDQGNCGSCWAFSTTGTMEGQYMKNERTSISFSEQQLVDCSGPW 167 +P++IDWR+ G VT VK+QG+CGSCWAFST T+E IS SEQ+LVDC Sbjct: 1 LPEQIDWRKKGAVTPVKNQGSCGSCWAFSTVSTVESINQIRTGNLISLSEQELVDCDKK- 59 Query: 168 GNNGCSGGLMENAYQY-LKQFGLETESSYPYTAVEGQCRYNKQLGVAKVTGYYTVHSGSE 226 N+GC GG AYQY + G++T+++YPY AV+G C+ + V + GY V +E Sbjct: 60 -NHGCLGGAFVFAYQYIINNGGIDTQANYPYKAVQGPCQAASK--VVSIDGYNGVPFCNE 116 Query: 227 VELKNLVGARRPAAVAVDVES-DFMMYRSGIYQSQTCSPLRVNHAVLAVGYGTQGGTDYW 285 LK V A +P+ VA+D S F Y SGI+ + ++NH V VGY +YW Sbjct: 117 XALKQAV-AVQPSTVAIDASSAQFQQYSSGIFSGPCGT--KLNHGVTIVGY----QANYW 169 Query: 286 IVKNSWGTYWGERGYIRMARNRG-NMCGIASLASLPMVA 323 IV+NSWG YWGE+GYIRM R G +CGIA L P A Sbjct: 170 IVRNSWGRYWGEKGYIRMLRVGGCGLCGIARLPYYPTKA 208 >2BDZ-A nrPDB Length = 214 Score = 272 bits (696), Expect = 1e-73, Method: Composition-based stats. Identities = 89/219 (40%), Positives = 121/219 (55%), Gaps = 14/219 (6%) Query: 109 PDKIDWRESGYVTEVKDQGNCGSCWAFSTTGTMEGQYMKNERTSISFSEQQLVDCSGPWG 168 P+ IDWRE G VT VK+Q CGSCWAFST T+EG IS SEQ+L+DC Sbjct: 2 PESIDWREKGAVTPVKNQNPCGSCWAFSTVATIEGINKIITGQLISLSEQELLDCERR-- 59 Query: 169 NNGCSGGLMENAYQYLKQFGLETESSYPYTAVEGQCRY-NKQLGVAKVTGYYTVHSGSEV 227 ++GC GG + QY+ G+ TE YPY +G+CR +K+ +TGY V + E+ Sbjct: 60 SHGCDGGYQTTSLQYVVDNGVHTEREYPYEKKQGRCRAKDKKGPKVYITGYKYVPANDEI 119 Query: 228 ELKNLVGARRPAAVAVDVESD-FMMYRSGIYQSQTCSPLRVNHAVLAVGYGTQGGTDYWI 286 L + A +P +V D F Y+ GIY+ + +HAV AVGYG Y + Sbjct: 120 SLIQAI-ANQPVSVVTDSRGRGFQFYKGGIYEGPCGT--NTDHAVTAVGYGKT----YLL 172 Query: 287 VKNSWGTYWGERGYIRMARNRG---NMCGIASLASLPMV 322 +KNSWG WGE+GYIR+ R G CG+ + + P+ Sbjct: 173 LKNSWGPNWGEKGYIRIKRASGRSKGTCGVYTSSFFPIK 211 >1PPO-A nrPDB Length = 216 Score = 269 bits (689), Expect = 1e-72, Method: Composition-based stats. Identities = 89/221 (40%), Positives = 128/221 (57%), Gaps = 10/221 (4%) Query: 108 VPDKIDWRESGYVTEVKDQGNCGSCWAFSTTGTMEGQYMKNERTSISFSEQQLVDCSGPW 167 +P+ +DWR+ G VT V+ QG+CGSCWAFS T+EG + SEQ+LVDC Sbjct: 1 LPENVDWRKKGAVTPVRHQGSCGSCWAFSAVATVEGINKIRTGKLVELSEQELVDCERR- 59 Query: 168 GNNGCSGGLMENAYQYLKQFGLETESSYPYTAVEGQCRYNKQLG-VAKVTGYYTVHSGSE 226 ++GC GG A +Y+ + G+ S YPY A +G CR + G + K +G V +E Sbjct: 60 -SHGCKGGYPPYALEYVAKNGIHLRSKYPYKAKQGTCRAKQVGGPIVKTSGVGRVQPNNE 118 Query: 227 VELKNLVGARRPAAVAVDVES-DFMMYRSGIYQSQTCSPLRVNHAVLAVGYGTQGGTDYW 285 L N + A++P +V V+ + F +Y+ GI++ + +V+HAV AVGYG GG Y Sbjct: 119 GNLLNAI-AKQPVSVVVESKGRPFQLYKGGIFEGPCGT--KVDHAVTAVGYGKSGGKGYI 175 Query: 286 IVKNSWGTYWGERGYIRMARNRGNM---CGIASLASLPMVA 323 ++KNSWGT WGE+GYIR+ R GN CG+ + P Sbjct: 176 LIKNSWGTAWGEKGYIRIKRAPGNSPGVCGLYKSSYYPTKN 216 >6MIS-A nrPDB Length = 215 Score = 269 bits (688), Expect = 1e-72, Method: Composition-based stats. Identities = 87/220 (39%), Positives = 125/220 (56%), Gaps = 11/220 (5%) Query: 108 VPDKIDWRESGYVTEVKDQGNCGSCWAFSTTGTMEGQYMKNERTSISFSEQQLVDCSGPW 167 VP IDWR+SG VT VK+QG CGSCWAF++ T+E Y +S SEQQ++DC+ + Sbjct: 1 VPQSIDWRDSGAVTSVKNQGRCGSCWAFASIATVESIYKIKRGNLVSLSEQQVLDCAVSY 60 Query: 168 GNNGCSGGLMENAYQY-LKQFGLETESSYPYTAVEGQCRYNKQLGVAKVTGYYTVHSGSE 226 GC GG + AY + + G+ + + YPY A +G C+ N A +T Y V +E Sbjct: 61 ---GCKGGWINKAYSFIISNKGVASAAIYPYKAAKGTCKTNGVPNSAYITRYTYVQRNNE 117 Query: 227 VELKNLVGARRPAAVAVDVESDFMMYRSGIYQSQTCSPLRVNHAVLAVGYG-TQGGTDYW 285 + V +P A A+D +F Y+ G++ + R+NHA++ +GYG G +W Sbjct: 118 RNMMYAVS-NQPIAAALDASGNFQHYKRGVFTGPCGT--RLNHAIVIIGYGQDSSGKKFW 174 Query: 286 IVKNSWGTYWGERGYIRMARNRG---NMCGIASLASLPMV 322 IV+NSWG WGE GYIR+AR+ +CGIA P + Sbjct: 175 IVRNSWGAGWGEGGYIRLARDVSSSFGLCGIAMDPLYPTL 214 >2CIO-A nrPDB Length = 212 Score = 266 bits (679), Expect = 1e-71, Method: Composition-based stats. Identities = 86/221 (38%), Positives = 126/221 (57%), Gaps = 14/221 (6%) Query: 108 VPDKIDWRESGYVTEVKDQGNCGSCWAFSTTGTMEGQYMKNERTSISFSEQQLVDCSGPW 167 +P+ +DWR+ G VT VK+QG+CGSCWAFS T+EG +SEQ+L+DC Sbjct: 1 IPEYVDWRQKGAVTPVKNQGSCGSCWAFSAVVTIEGIIKIRTGNLNQYSEQELLDCDRR- 59 Query: 168 GNNGCSGGLMENAYQYLKQFGLETESSYPYTAVEGQCRYNKQLGV-AKVTGYYTVHSGSE 226 + GC+GG +A Q + Q+G+ ++YPY V+ CR ++ AK G V +E Sbjct: 60 -SYGCNGGYPWSALQLVAQYGIHYRNTYPYEGVQRYCRSREKGPYAAKTDGVRQVQPYNE 118 Query: 227 VELKNLVGARRPAAVAVDVES-DFMMYRSGIYQSQTCSPLRVNHAVLAVGYGTQGGTDYW 285 L + A +P +V ++ DF +YR GI+ + +V+HAV AVGYG +Y Sbjct: 119 GALLYSI-ANQPVSVVLEAAGKDFQLYRGGIFVGPCGN--KVDHAVAAVGYG----PNYI 171 Query: 286 IVKNSWGTYWGERGYIRMARNRGNM---CGIASLASLPMVA 323 ++KNSWGT WGE GYIR+ R GN CG+ + + P+ Sbjct: 172 LIKNSWGTGWGENGYIRIKRGTGNSYGVCGLYTSSFYPVKN 212 >1XKG-A nrPDB Length = 312 Score = 265 bits (677), Expect = 2e-71, Method: Composition-based stats. Identities = 88/302 (29%), Positives = 142/302 (47%), Gaps = 28/302 (9%) Query: 16 SNDDLWHQWKRMYNKEYNGADDQ--HRRNIWEKNVKHIQEHNLRHDLGLVTYTLGLNQFT 73 S+ + ++K+ +NK Y +D+ R+N E +VK++Q + +N + Sbjct: 3 SSIKTFEEYKKAFNKSYATFEDEEAARKNFLE-SVKYVQSNGG-----------AINHLS 50 Query: 74 DMTFEEFKAKYLTEMSRASDILSHGVPYEAN------NRAVPDKIDWRESGYVTEVKDQG 127 D++ +EFK ++L + A + L A N P +ID R+ VT ++ QG Sbjct: 51 DLSLDEFKNRFLMS-AEAFEHLKTQFDLNAETNACSINGNAPAEIDLRQMRTVTPIRMQG 109 Query: 128 NCGSCWAFSTTGTMEGQYMKNERTSISFSEQQLVDCSGPWGNNGCSGGLMENAYQYLKQF 187 CGS WAFS E Y+ S+ +EQ+LVDC+ +GC G + +Y++ Sbjct: 110 GCGSAWAFSGVAATESAYLAYRDQSLDLAEQELVDCAS---QHGCHGDTIPRGIEYIQHN 166 Query: 188 GLETESSYPYTAVEGQCRYNKQLGVAKVTGYYTVHSGSEVELKNLVGA-RRPAAVAVDVE 246 G+ ES Y Y A E CR ++ Y ++ + +++ + AV + ++ Sbjct: 167 GVVQESYYRYVAREQSCRRPNAQRFG-ISNYCQIYPPNANKIREALAQTHSAIAVIIGIK 225 Query: 247 S-DFMMYRSGIYQSQTCSPLRVN-HAVLAVGYGTQGGTDYWIVKNSWGTYWGERGYIRMA 304 D + G Q + + N HAV VGY G DYWIV+NSW T WG+ GY A Sbjct: 226 DLDAFRHYDGRTIIQRDNGYQPNYHAVNIVGYSNAQGVDYWIVRNSWDTNWGDNGYGYFA 285 Query: 305 RN 306 N Sbjct: 286 AN 287 >5A24-A nrPDB Length = 222 Score = 263 bits (672), Expect = 8e-71, Method: Composition-based stats. Identities = 95/224 (42%), Positives = 119/224 (53%), Gaps = 13/224 (5%) Query: 108 VPDKIDWRESGYVTEVKDQGNCGSCWAFSTTGTMEGQYMKNERTSISFSEQQLVDCSGPW 167 VP +DWR +G VT VK+Q CG CWAFS +EG T S SE+Q+VDC Sbjct: 1 VPAAVDWRTAGAVTPVKNQQQCGCCWAFSAVAAIEGATQIKTGTLTSLSEEQIVDCDTNG 60 Query: 168 GNNGCSGGLMENAYQYLKQF-GLETESSYPYTAV---EGQCRYNKQLGVAKVTGYYTVHS 223 + GC+GG + A+QY+ G++TES YPYTA G C + A +TGY V + Sbjct: 61 NDKGCNGGTPDGAFQYVVNNQGIDTESDYPYTAGGGSPGTCSASSYQPAASITGYQDVPA 120 Query: 224 GSEVELKNLVGARRPAAVAVDVES-DFMMYRSGIYQSQTCSPLRVNHAVLAVGYGTQ--G 280 +E A +P +VA+D F Y SGIY ++HAV VGYGT Sbjct: 121 NNEQA-LQQAAATQPISVAIDASDPSFQSYSSGIYSGPC--NTNLDHAVTVVGYGTDPNS 177 Query: 281 GTDYWIVKNSWGTYWGERGYIRMARNRG---NMCGIASLASLPM 321 G YWIVKNSWGT WG+ GYI M +CGIA AS P Sbjct: 178 GNSYWIVKNSWGTSWGQEGYIWMQMGLNAPYGVCGIAMQASYPT 221 >4YYQ-A nrPDB Length = 217 Score = 263 bits (671), Expect = 1e-70, Method: Composition-based stats. Identities = 87/220 (39%), Positives = 132/220 (60%), Gaps = 9/220 (4%) Query: 108 VPDKIDWRESGYVTEVKDQGNCGSCWAFSTTGTMEGQYMKNERTSISFSEQQLVDCSGPW 167 +P+ +DWR G V +++QG CGSCWAFS +E +S SEQQL+DC+ + Sbjct: 1 LPETVDWRSKGAVNPIRNQGQCGSCWAFSAVAAVESINKIVTGQLLSLSEQQLLDCAQSY 60 Query: 168 GNNGCSGGLMENAYQY-LKQFGLETESSYPYTAVEGQCRYNKQLGVAKVTGYYTVHSGSE 226 N GC GG + A++Y ++ G+ ++S+YPYT +GQCR +A + Y V S +E Sbjct: 61 KNLGCQGGWVNKAFEYIIQNRGITSQSNYPYTGHKGQCR-TGLASIATIDSYQYVPSNNE 119 Query: 227 VELKNLVGARRPAAVAVDVES-DFMMYRSGIYQSQTCSPLRVNHAVLAVGYGTQGGTDYW 285 LKN V A +P +VAV+ F +Y+SG++ + ++HAV+ +GYG G DYW Sbjct: 120 NALKNAV-ANQPVSVAVEAAGRAFQLYKSGVFTGSCG--VAIDHAVVLIGYGKYNGVDYW 176 Query: 286 IVKNSWGTYWGERGYIRMARN---RGNMCGIASLASLPMV 322 +++NSWGT WGE+GY+++ RN CG+A L P+ Sbjct: 177 LLRNSWGTNWGEQGYMKLQRNVAQSAGKCGVARLCLYPVK 216 >1GEC-E nrPDB Length = 216 Score = 259 bits (662), Expect = 1e-69, Method: Composition-based stats. Identities = 90/221 (40%), Positives = 121/221 (54%), Gaps = 10/221 (4%) Query: 108 VPDKIDWRESGYVTEVKDQGNCGSCWAFSTTGTMEGQYMKNERTSISFSEQQLVDCSGPW 167 +P+ +DWR G VT VK QG C SCWAFST T+EG + SEQ+LVDC Sbjct: 1 LPESVDWRAKGAVTPVKHQGYCESCWAFSTVATVEGINKIKTGNLVELSEQELVDCD--L 58 Query: 168 GNNGCSGGLMENAYQYLKQFGLETESSYPYTAVEGQCRYNKQLGV-AKVTGYYTVHSGSE 226 + GC+ G + QY+ Q G+ + YPY A + CR N+ G K G V S +E Sbjct: 59 QSYGCNRGYQSTSLQYVAQNGIHLRAKYPYIAKQQTCRANQVGGPKVKTNGVGRVQSNNE 118 Query: 227 VELKNLVGARRPAAVAVDVES-DFMMYRSGIYQSQTCSPLRVNHAVLAVGYGTQGGTDYW 285 L N + A +P +V V+ DF Y+ GI++ + +V+HAV AVGYG GG Y Sbjct: 119 GSLLNAI-AHQPVSVVVESAGRDFQNYKGGIFEGSCGT--KVDHAVTAVGYGKSGGKGYI 175 Query: 286 IVKNSWGTYWGERGYIRMARNRGNM---CGIASLASLPMVA 323 ++KNSWG WGE GYIR+ R GN CG+ + P+ Sbjct: 176 LIKNSWGPGWGENGYIRIRRASGNSPGVCGVYRSSYYPIKN 216 >2B1M-A nrPDB Length = 246 Score = 258 bits (659), Expect = 2e-69, Method: Composition-based stats. Identities = 85/228 (37%), Positives = 121/228 (53%), Gaps = 14/228 (6%) Query: 108 VPDKIDWRESGYVTEVKDQGNCGSCWAFSTTGTMEGQYMKNERTSISFSEQQLVDCSGPW 167 P+ DW + G +T+VK QG CGS WAFS TG +E + +S SEQ+L+DC Sbjct: 2 APESWDWSKKGVITKVKFQGQCGSGWAFSATGAIEAAHAIATGNLVSLSEQELIDCVDE- 60 Query: 168 GNNGCSGGLMENAYQY-LKQFGLETESSYPYTAVEGQCRYNKQLGVAKVTGY------YT 220 + GC G ++++ +K G+ +E+ YPY A +G+C+ N+ + Y Sbjct: 61 -SEGCYNGWHYQSFEWVVKHGGIASEADYPYKARDGKCKANEIQDKVTIDNYGVQILSNE 119 Query: 221 VHSGSEVELKNLVGARRPAAVAVDVESDFMMYRSGIYQSQTC-SPLRVNHAVLAVGYGTQ 279 +P +V++D DF Y GIY C SP +NH VL VGYG++ Sbjct: 120 STESEAESSLQSFVLEQPISVSIDA-KDFHFYSGGIYDGGNCSSPYGINHFVLIVGYGSE 178 Query: 280 GGTDYWIVKNSWGTYWGERGYIRMARNRGNM---CGIASLASLPMVAR 324 G DYWI KNSWG WG GYIR+ RN GN+ CG+ AS P++ + Sbjct: 179 DGVDYWIAKNSWGEDWGIDGYIRIQRNTGNLLGVCGMNYFASYPIIEK 226 >1JQP-A nrPDB Length = 438 Score = 254 bits (649), Expect = 4e-68, Method: Composition-based stats. Identities = 97/335 (28%), Positives = 148/335 (44%), Gaps = 42/335 (12%) Query: 18 DDLWHQWKRMYNKEYNGADDQ------HRRNIWEK--NVKHIQEHNLRHDLGLVTYTLGL 69 D L W K+ ++ H + EK + HN + V Sbjct: 104 DVLGRNWACFVGKKMANHSEKVYVNVAHLGGLQEKYSERLYSHHHNFVKAINSVQ----- 158 Query: 70 NQFTDMTFEEFKAKYLTEMSRASDIL---------SHGVPYEANNRAVPDKIDWRES--- 117 +T T+ ++ + ++ R S + ++P+ DWR Sbjct: 159 KSWTATTYRRYEKLSIRDLIRRSGHSGRILRPKPAPITDEIQQQILSLPESWDWRNVRGI 218 Query: 118 GYVTEVKDQGNCGSCWAFSTTGTMEGQYMK--NERTSISFSEQQLVDCSGPWGNNGCSGG 175 +V+ V++Q +CGSC++F++ G +E + N + S Q++V CS GC GG Sbjct: 219 NFVSPVRNQESCGSCYSFASLGMLEARIRILTNNSQTPILSPQEVVSCSP--YAQGCDGG 276 Query: 176 LME-NAYQYLKQFGLETESSYPYTAVEGQCRYNKQLGVAKVTGYYTVHS----GSEVELK 230 A +Y + FG+ E+ +PYTA + C+ + + YY V +E +K Sbjct: 277 FPYLIAGKYAQDFGVVEENCFPYTATDAPCKPKENCLRYYSSEYYYVGGFYGGCNEALMK 336 Query: 231 NLVGARRPAAVAVDVESDFMMYRSGIYQS----QTCSPLRV-NHAVLAVGYGTQ--GGTD 283 + P AVA +V DF+ Y SGIY +P + NHAVL VGYG G D Sbjct: 337 LELVKHGPMAVAFEVHDDFLHYHSGIYHHTGLSDPFNPFELTNHAVLLVGYGKDPVTGLD 396 Query: 284 YWIVKNSWGTYWGERGYIRMARNRGNMCGIASLAS 318 YWIVKNSWG+ WGE GY R+ R + C I S+A Sbjct: 397 YWIVKNSWGSQWGESGYFRIRRGT-DECAIESIAM 430 >1ICF-A nrPDB Length = 175 Score = 252 bits (644), Expect = 1e-67, Method: Composition-based stats. Identities = 86/175 (49%), Positives = 108/175 (61%), Gaps = 3/175 (1%) Query: 108 VPDKIDWRESGYVTEVKDQGNCGSCWAFSTTGTMEGQYMKNERTSISFSEQQLVDCSGPW 167 P +DWRE GYVT VK+QG CGSCWAFS TG +EGQ + IS SEQ LVDCSGP Sbjct: 1 APRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQ 60 Query: 168 GNNGCSGGLMENAYQYLK-QFGLETESSYPYTAVEGQCRYNKQLGVAKVTGYYTVHSGSE 226 GN GC+GGLM+ A+QY++ GL++E SYPY A E C+YN + VA TG+ + E Sbjct: 61 GNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPK-QE 119 Query: 227 VELKNLVGARRPAAVAVDV-ESDFMMYRSGIYQSQTCSPLRVNHAVLAVGYGTQG 280 L V P +VA+D F+ Y+ GIY CS ++H VL VGYG + Sbjct: 120 KALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFES 174 >3U8E-A nrPDB Length = 222 Score = 250 bits (638), Expect = 7e-67, Method: Composition-based stats. Identities = 93/225 (41%), Positives = 125/225 (55%), Gaps = 14/225 (6%) Query: 108 VPDKIDWRESGYVTEVKDQGNCGSCWAFSTTGTMEGQYMKNERTSISFSEQQLVDCSGPW 167 P IDWR+ G VT VKDQG CG CWAF TG +EG IS SEQQ+VDC Sbjct: 1 APASIDWRKKGAVTSVKDQGACGMCWAFGATGAIEGIDAITTGRLISVSEQQIVDCDTXX 60 Query: 168 GNNGCSGGLMENAYQY-LKQFGLETESSYPYTAVEGQCRYNKQLGVAKVTGYYTVHSGSE 226 GG ++A+++ + G+ ++++YPYT V+G C NK + A++ GY V S Sbjct: 61 XXX--XGGDADDAFRWVITNGGIASDANYPYTGVDGTCDLNKPI-AARIDGYTNVP-NSS 116 Query: 227 VELKNLVGARRPAAVAVDVES-DFMMYRS-GIYQSQTC--SPLRVNHAVLAVGYGTQG-G 281 L + V A++P +V + S F +Y GI+ +C P V+H VL VGYG+ G Sbjct: 117 SALLDAV-AKQPVSVNIYTSSTSFQLYTGPGIFAGSSCSDDPATVDHTVLIVGYGSNGTN 175 Query: 282 TDYWIVKNSWGTYWGERGYIRMARNRG---NMCGIASLASLPMVA 323 DYWIVKNSWGT WG GYI + RN +C I + S P + Sbjct: 176 ADYWIVKNSWGTEWGIDGYILIRRNTNRPDGVCAIDAWGSYPTKS 220 >3PBH-A nrPDB Length = 317 Score = 249 bits (635), Expect = 2e-66, Method: Composition-based stats. Identities = 82/317 (25%), Positives = 132/317 (41%), Gaps = 55/317 (17%) Query: 48 VKHIQEHNLRHDLGLVTYTLGLNQFTDMTFEEFKAKYLTEMSRASDILSHGVPYEANNRA 107 V ++ + N G Y + DM++ + + + Sbjct: 15 VNYVNKRNTTWQAGHNFYNV------DMSYLKRLCGTFLGGPKPP-----QRVMFTEDLK 63 Query: 108 VPDKID----WRESGYVTEVKDQGNCGSCWAFSTTGTMEGQYMK--NERTSISFSEQQLV 161 +P D W + + E++DQG+CGSCWAF + + N S+ S + L+ Sbjct: 64 LPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLL 123 Query: 162 DCSGPWGNNGCSGGLMENAYQYLKQFGLETESSY----------------------PYTA 199 C G +GC+GG A+ + + GL + Y P Sbjct: 124 TCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCT 183 Query: 200 VEG---QCR------YNKQLGVAKVTGY--YTVHSGSEVELKNLVGARRPAAVAVDVESD 248 EG +C Y+ K GY Y+V S SE ++ + P A V SD Sbjct: 184 GEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSV-SNSEKDIMAEIYKNGPVEGAFSVYSD 242 Query: 249 FMMYRSGIYQSQTCSPLRVNHAVLAVGYGTQGGTDYWIVKNSWGTYWGERGYIRMARNRG 308 F++Y+SG+YQ T + HA+ +G+G + GT YW+V NSW T WG+ G+ ++ R + Sbjct: 243 FLLYKSGVYQHVTG-EMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRGQ- 300 Query: 309 NMCGIAS--LASLPMVA 323 + CGI S +A +P Sbjct: 301 DHCGIESEVVAGIPRTD 317 >6EXO-A nrPDB Length = 215 Score = 248 bits (633), Expect = 3e-66, Method: Composition-based stats. Identities = 90/221 (40%), Positives = 119/221 (53%), Gaps = 13/221 (5%) Query: 108 VPDKIDWRESGYVTEVKDQGNCGSCWAFSTTGTMEGQYMKNERTSISFSEQQLVDCSGPW 167 P +DWRE G VT VKDQG CGSCWAFST G +EGQ+ +S SEQ LV C Sbjct: 1 APAAVDWREKGAVTPVKDQGQCGSCWAFSTIGNIEGQWQVAGNPLVSLSEQMLVSCDTI- 59 Query: 168 GNNGCSGGLMENAYQYLKQ---FGLETESSYPYTAVEG---QCRYNKQLGVAKVTGYYTV 221 + GC GGLM+NA+ ++ + TE+SYPY + G QC+ N A +T + + Sbjct: 60 -DFGCGGGLMDNAFNWIVNSNGGNVFTEASYPYVSGNGEQPQCQMNGHEIGAAITDHVDL 118 Query: 222 HSGSEVELKNLVGARRPAAVAVDVESDFMMYRSGIYQSQTCSPLRVNHAVLAVGYGTQGG 281 E + + P A+AVD S FM Y GI +C+ +++H VL VGY Sbjct: 119 PQ-DEDAIAAYLAENGPLAIAVDATS-FMDYNGGILT--SCTSEQLDHGVLLVGYNDASN 174 Query: 282 TDYWIVKNSWGTYWGERGYIRMARNRGNMCGIASLASLPMV 322 YWI+KNSW WGE GYIR+ + N C + S +V Sbjct: 175 PPYWIIKNSWSNMWGEDGYIRIEKGT-NQCLMNQAVSSAVV 214 >3IOQ-A nrPDB Length = 213 Score = 245 bits (625), Expect = 2e-65, Method: Composition-based stats. Identities = 86/222 (38%), Positives = 118/222 (53%), Gaps = 14/222 (6%) Query: 108 VPDKIDWRESGYVTEVKDQGNCGSCWAFSTTGTMEGQYMKNERTSISFSEQQLVDCSGPW 167 +P IDWR+ G VT V++QG CGSCW FS+ +EG +S SEQ+L+DC Sbjct: 1 IPTSIDWRQKGAVTPVRNQGGCGSCWTFSSVAAVEGINKIVTGQLLSLSEQELLDCERR- 59 Query: 168 GNNGCSGGLMENAYQYLKQFGLETESSYPYTAVEGQCRYNK-QLGVAKVTGYYTVHSGSE 226 + GC GG A QY+ G+ YPY V+ QCR ++ + K G V +E Sbjct: 60 -SYGCRGGFPLYALQYVANSGIHLRQYYPYEGVQRQCRASQAKGPKVKTDGVGRVPRNNE 118 Query: 227 VELKNLVGARRPAAVAVDVES-DFMMYRSGIYQSQTCSPLRVNHAVLAVGYGTQGGTDYW 285 L + A +P ++ V+ + F YR GI+ + ++HAV AVGYG DY Sbjct: 119 QALIQRI-AIQPVSIVVEAKGRAFQNYRGGIFAGPCGTS--IDHAVAAVGYGN----DYI 171 Query: 286 IVKNSWGTYWGERGYIRMARNRGN---MCGIASLASLPMVAR 324 ++KNSWGT WGE GYIR+ R GN CG+ S + P R Sbjct: 172 LIKNSWGTGWGEGGYIRIKRGSGNPQGACGVLSDSVFPTKNR 213 >4PI3-A nrPDB Length = 216 Score = 244 bits (622), Expect = 5e-65, Method: Composition-based stats. Identities = 89/221 (40%), Positives = 119/221 (53%), Gaps = 13/221 (5%) Query: 108 VPDKIDWRESGYVTEVKDQGNCGSCWAFSTTGTMEGQYMKNERTSISFSEQQLVDCSGPW 167 P +DWR G VT VKDQG CGSCWAFS G +E Q+ + SEQ LV C Sbjct: 2 APAAVDWRARGAVTAVKDQGQCGSCWAFSAIGNVECQWFLAGHPLTNLSEQMLVSCDKT- 60 Query: 168 GNNGCSGGLMENAYQYL---KQFGLETESSYPYTAVEG---QCRYNKQLGVAKVTGYYTV 221 ++GCSGGLM NA++++ + TE SYPY + EG C + A +TG+ + Sbjct: 61 -DSGCSGGLMNNAFEWIVQENNGAVYTEDSYPYASGEGISPPCTTSGHTVGATITGHVEL 119 Query: 222 HSGSEVELKNLVGARRPAAVAVDVESDFMMYRSGIYQSQTCSPLRVNHAVLAVGYGTQGG 281 E ++ + P AVAVD S +M Y G+ +C +++H VL VGY Sbjct: 120 PQ-DEAQIAAWLAVNGPVAVAVDASS-WMTYTGGVMT--SCVSEQLDHGVLLVGYNDSAA 175 Query: 282 TDYWIVKNSWGTYWGERGYIRMARNRGNMCGIASLASLPMV 322 YWI+KNSW T WGE GYIR+A+ N C + AS +V Sbjct: 176 VPYWIIKNSWTTQWGEEGYIRIAKGS-NQCLVKEEASSAVV 215 >3CBK-A nrPDB Length = 266 Score = 243 bits (621), Expect = 6e-65, Method: Composition-based stats. Identities = 73/263 (27%), Positives = 117/263 (44%), Gaps = 42/263 (15%) Query: 103 ANNRAVPDKID----WRESGYVTEVKDQGNCGSCWAFSTTGTMEGQYMK--NERTSISFS 156 + +P D W + + E++DQG+CGS WAF + + N S+ S Sbjct: 2 TEDLKLPASFDAREQWPQCPTIKEIRDQGSCGSAWAFGAVEAISDRICIHTNAHVSVEVS 61 Query: 157 EQQLVDCSGPWGNNGCSGGLMENAYQYLKQFGLETESSY--------------------- 195 + L+ C G +GC+GG A+ + + GL + Y Sbjct: 62 AEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEAHVNGA 121 Query: 196 -PYTAVEG---QCR------YNKQLGVAKVTGYYTVH-SGSEVELKNLVGARRPAAVAVD 244 P EG +C Y+ K GY + S SE ++ + P A Sbjct: 122 RPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFS 181 Query: 245 VESDFMMYRSGIYQSQTCSPLRVNHAVLAVGYGTQGGTDYWIVKNSWGTYWGERGYIRMA 304 V SDF++Y+SG+YQ T + HA+ +G+G + GT YW+V NSW T WG+ G+ ++ Sbjct: 182 VYSDFLLYKSGVYQHVTG-EMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKIL 240 Query: 305 RNRGNMCGIAS--LASLPMVARF 325 R + + CGI S +A +P ++ Sbjct: 241 RGQ-DHCGIESEVVAGIPRTDQY 262 >4HWY-A nrPDB Length = 340 Score = 242 bits (619), Expect = 1e-64, Method: Composition-based stats. Identities = 75/283 (26%), Positives = 109/283 (38%), Gaps = 36/283 (12%) Query: 72 FTDMTFEEFKAK--YLTEMSRASDILSHGVPYEANNRAVPDKID----WRESGYVTEVKD 125 ++T E K + + + AS + E +P D W + ++ D Sbjct: 56 MQNITLREAKRLNGVIKKNNNASILPKRRFTEEEARAPLPSSFDSAEAWPNCPTIPQIAD 115 Query: 126 QGNCGSCWAFSTTGTMEGQYMKNER-TSISFSEQQLVDCSGPWGNNGCSGGLMENAYQYL 184 Q CGSCWA + M ++ + S L+ C G +GC+GG + A+ Y Sbjct: 116 QSACGSCWAVAAASAMSDRFCTMGGVQDVHISAGDLLACCSDCG-DGCNGGDPDRAWAYF 174 Query: 185 KQFGLETESSYPYTAVE---------------------GQCRYNKQLGVAKVTGYYTVHS 223 GL ++ PY +C Y V Y + S Sbjct: 175 SSTGLVSDYCQPYPFPHCSHHSKSKNGYPPCSQFNFDTPKCNYTCDDPTIPVVNYRSWTS 234 Query: 224 GS---EVELKNLVGARRPAAVAVDVESDFMMYRSGIYQSQTCSPLRVNHAVLAVGYGTQG 280 + E + + R P VA DV DF+ Y SG+Y + L HAV VG+GT Sbjct: 235 YALQGEDDYMRELFFRGPFEVAFDVYEDFIAYNSGVYHHVSGQYLG-GHAVRLVGWGTSN 293 Query: 281 GTDYWIVKNSWGTYWGERGYIRMARNRGNMCGIA--SLASLPM 321 G YW + NSW T WG GY + R CGI A +P+ Sbjct: 294 GVPYWKIANSWNTEWGMDGYFLIRRGSS-ECGIEDGGSAGIPL 335 >1MIR-A nrPDB Length = 322 Score = 239 bits (611), Expect = 9e-64, Method: Composition-based stats. Identities = 71/263 (26%), Positives = 116/263 (44%), Gaps = 42/263 (15%) Query: 103 ANNRAVPDKID----WRESGYVTEVKDQGNCGSCWAFSTTGTMEGQYMK--NERTSISFS 156 + + +P+ D W + +++DQG+CGS WAF M + N R ++ S Sbjct: 58 SEDINLPESFDAREQWSNCPTIAQIRDQGSCGSSWAFGAVEAMSDRICIHTNGRVNVEVS 117 Query: 157 EQQLVDCSGPWGNNGCSGGLMENAYQYLKQFGLETESSY--------------------- 195 + L+ C G +GC+GG A+ + + GL + Y Sbjct: 118 AEDLLTCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNGA 177 Query: 196 -PYTAVEG---QCRYNKQLGVA------KVTGYYTVH-SGSEVELKNLVGARRPAAVAVD 244 P EG +C + G + K GY + S SE E+ + P A Sbjct: 178 RPPCTGEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFT 237 Query: 245 VESDFMMYRSGIYQSQTCSPLRVNHAVLAVGYGTQGGTDYWIVKNSWGTYWGERGYIRMA 304 V SDF+ Y+SG+Y+ + + HA+ +G+G + G YW+V NSW WG+ G+ ++ Sbjct: 238 VFSDFLTYKSGVYKHEAGD-VMGGHAIRILGWGIENGVPYWLVANSWNADWGDNGFFKIL 296 Query: 305 RNRGNMCGIAS--LASLPMVARF 325 R N CGI S +A +P ++ Sbjct: 297 RGE-NHCGIESEIVAGIPRTQQY 318 >1CPJ-A nrPDB Length = 260 Score = 237 bits (605), Expect = 4e-63, Method: Composition-based stats. Identities = 72/260 (27%), Positives = 115/260 (44%), Gaps = 42/260 (16%) Query: 103 ANNRAVPDKID----WRESGYVTEVKDQGNCGSCWAFSTTGTMEGQYMK--NERTSISFS 156 + + +P+ D W + +++DQG+CGSCWAF M + N R ++ S Sbjct: 2 SEDINLPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVS 61 Query: 157 EQQLVDCSGPWGNNGCSGGLMENAYQYLKQFGLETESSY--------------------- 195 + L+ C G +GC+GG A+ + + GL + Y Sbjct: 62 AEDLLTCCGIQCGDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIPPCEHHVNGA 121 Query: 196 -PYTAVEG---QCRYNKQLGVA------KVTGYYTVH-SGSEVELKNLVGARRPAAVAVD 244 P EG +C + G + K GY + S SE E+ + P A Sbjct: 122 RPPCTGEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFT 181 Query: 245 VESDFMMYRSGIYQSQTCSPLRVNHAVLAVGYGTQGGTDYWIVKNSWGTYWGERGYIRMA 304 V SDF+ Y+SG+Y+ + + HA+ +G+G + G YW+V NSW WG+ G+ ++ Sbjct: 182 VFSDFLTYKSGVYKHEAGD-VMGGHAIRILGWGIENGVPYWLVANSWNADWGDNGFFKIL 240 Query: 305 RNRGNMCGIAS--LASLPMV 322 R N CGI S +A +P Sbjct: 241 RGE-NHCGIESEIVAGIPRT 259 >3BPF-A nrPDB Length = 241 Score = 237 bits (604), Expect = 6e-63, Method: Composition-based stats. Identities = 80/229 (34%), Positives = 124/229 (54%), Gaps = 22/229 (9%) Query: 110 DKIDWRESGYVTEVKDQGNCGSCWAFSTTGTMEGQYMKNERTSISFSEQQLVDCSGPWGN 169 DWR VT VKDQ NCGSCWAFS+ G++E QY + I+ SEQ+LVDCS + N Sbjct: 20 AAYDWRLHSGVTPVKDQKNCGSCWAFSSIGSVESQYAIRKNKLITLSEQELVDCS--FKN 77 Query: 170 NGCSGGLMENAYQYLKQ-FGLETESSYPYTA-VEGQCRYNKQLGVAKVTGYYTVHSGSEV 227 GC+GGL+ NA++ + + G+ + YPY + C ++ + Y +V Sbjct: 78 YGCNGGLINNAFEDMIELGGICPDGDYPYVSDAPNLCNIDRCTEKYGIKNYLSVPDNK-- 135 Query: 228 ELKNLVGARRPAAVAVDVESDFMMYRSGIYQSQTCSPLRVNHAVLAVGYGTQGGTD---- 283 LK + P +++V V DF Y+ GI+ + ++NHAV+ VG+G + + Sbjct: 136 -LKEALRFLGPISISVAVSDDFAFYKEGIFDGECGD--QLNHAVMLVGFGMKEIVNPLTK 192 Query: 284 ------YWIVKNSWGTYWGERGYIRMARNRGNM---CGIASLASLPMVA 323 Y+I+KNSWG WGERG+I + + + CG+ + A +P++ Sbjct: 193 KGEKHYYYIIKNSWGQQWGERGFINIETDESGLMRKCGLGTDAFIPLIE 241 >3BPM-A nrPDB Length = 243 Score = 228 bits (581), Expect = 3e-60, Method: Composition-based stats. Identities = 79/228 (34%), Positives = 115/228 (50%), Gaps = 22/228 (9%) Query: 111 KIDWRESGYVTEVKDQGNCGSCWAFSTTGTMEGQYMKNERTSISFSEQQLVDCSGPWGNN 170 DWR G VT VKDQ CGSCWAFS+ G++E QY ++ FSEQ+LVDCS NN Sbjct: 23 AYDWRLHGGVTPVKDQALCGSCWAFSSVGSVESQYAIRKKALFLFSEQELVDCSVK--NN 80 Query: 171 GCSGGLMENAYQYLKQ-FGLETESSYPYTAV-EGQCRYNKQLGVAKVTGYYTVHSGSEVE 228 GC GG + NA+ + GL ++ YPY + C + + Y ++ + + Sbjct: 81 GCYGGYITNAFDDMIDLGGLCSQDDYPYVSNLPETCNLKRCNERYTIKSYVSIP---DDK 137 Query: 229 LKNLVGARRPAAVAVDVESDFMMYRSGIYQSQTCSPLRVNHAVLAVGYGTQGGTD----- 283 K + P ++++ DF YR G Y + NHAV+ VGYG + + Sbjct: 138 FKEALRYLGPISISIAASDDFAFYRGGFYDGECG--AAPNHAVILVGYGMKDIYNEDTGR 195 Query: 284 -----YWIVKNSWGTYWGERGYIRMARNRGN---MCGIASLASLPMVA 323 Y+I+KNSWG+ WGE GYI + + C I + A +P++ Sbjct: 196 MEKFYYYIIKNSWGSDWGEGGYINLETDENGYKKTCSIGTEAYVPLLE 243 >5VPK-A nrPDB Length = 223 Score = 226 bits (575), Expect = 1e-59, Method: Composition-based stats. Identities = 73/210 (34%), Positives = 101/210 (48%), Gaps = 11/210 (5%) Query: 104 NNRAVPDKIDWRESGYVTEVKDQGNCGSCWAFSTTGTMEGQYMKNERTSISFSEQQLVDC 163 N+ VP ++D R VT ++ QG CGSCWAFS E Y+ TS+ SEQ+LVDC Sbjct: 7 NSVNVPSELDLRSLRTVTPIRMQGGCGSCWAFSGVAATESAYLAYRNTSLDLSEQELVDC 66 Query: 164 SGPWGNNGCSGGLMENAYQYLKQFGLETESSYPYTAVEGQCRYNKQLGVAKVTGYYTVHS 223 + +GC G + +Y++Q G+ E SYPY A E QCR ++ Y ++ Sbjct: 67 AS---QHGCHGDTIPRGIEYIQQNGVVEERSYPYVAREQQCRRPNSQHYG-ISNYCQIYP 122 Query: 224 GSEVELKNLVGARRPAAVAVDVESD---FMMY--RSGIYQSQTCSPLRVNHAVLAVGYGT 278 +++ + A + D F Y R+ I P HAV VGYG+ Sbjct: 123 PDVKQIREALTQTHTAIAVIIGIKDLRAFQHYDGRTIIQHDNGYQPNY--HAVNIVGYGS 180 Query: 279 QGGTDYWIVKNSWGTYWGERGYIRMARNRG 308 G DYWIV+NSW T WG+ GY Sbjct: 181 TQGVDYWIVRNSWDTTWGDSGYGYFQAGNN 210 >4I05-A nrPDB Length = 285 Score = 223 bits (569), Expect = 8e-59, Method: Composition-based stats. Identities = 67/257 (26%), Positives = 101/257 (39%), Gaps = 42/257 (16%) Query: 99 VPYEANNRAVPDKID----WRESGYVTEVKDQGNCGSCWAFSTTGTMEGQYMK--NERTS 152 V + N +P D W + ++DQ CGSCWAF M + + + Sbjct: 25 VDHNDWNVEIPSSFDSRKKWPRCKSIATIRDQSRCGSCWAFGAVEAMSDRSCIQSGGKQN 84 Query: 153 ISFSEQQLVDCSGPWGNNGCSGGLMENAYQYLKQFGLETESS---------YPYTAVEGQ 203 + S L+ C G GC GG++ A+ Y + G+ T SS YP+ E Sbjct: 85 VELSAVDLLSCCESCG-LGCEGGILGPAWDYWVKEGIVTGSSKENHAGCEPYPFPKCEHH 143 Query: 204 CRYNKQLGVAKVTG-----------YYTVH-------------SGSEVELKNLVGARRPA 239 + +K+ Y T + E ++ + P Sbjct: 144 TKGKYPPCGSKIYKTPRCKQTCQKKYKTPYTQDKHRGKSSYNVKNDEKAIQKEIMKYGPV 203 Query: 240 AVAVDVESDFMMYRSGIYQSQTCSPLRVNHAVLAVGYGTQGGTDYWIVKNSWGTYWGERG 299 V DF+ Y+SGIY+ T L HA+ +G+G + YW++ NSW WGE G Sbjct: 204 EAGFTVYEDFLNYKSGIYKHITGETLG-GHAIRIIGWGVENKAPYWLIANSWNEDWGENG 262 Query: 300 YIRMARNRGNMCGIASL 316 Y R+ R R + C I S Sbjct: 263 YFRIVRGR-DECSIESE 278 >1M6D-A nrPDB Length = 214 Score = 222 bits (566), Expect = 1e-58, Method: Composition-based stats. Identities = 91/219 (41%), Positives = 125/219 (57%), Gaps = 8/219 (3%) Query: 108 VPDKIDWRESGYVTEVKDQGNCGSCWAFSTTGTMEGQYMKNERTSISFSEQQLVDCSGPW 167 P + DWR G VT+VKDQG CGSCWAFS TG +EGQ+ N+ T +S SEQ+L+DC Sbjct: 1 APPEWDWRSKGAVTKVKDQGMCGSCWAFSVTGNVEGQWFLNQGTLLSLSEQELLDCDKM- 59 Query: 168 GNNGCSGGLMENAYQYLKQ-FGLETESSYPYTAVEGQCRYNKQLGVAKVTGYYTVHSGSE 226 + C GGL NAY +K GLETE Y Y C+++ + + + S +E Sbjct: 60 -DKACMGGLPSNAYSAIKNLGGLETEDDYSYQGHMQSCQFSAEKAKVYIQDSVEL-SQNE 117 Query: 227 VELKNLVGARRPAAVAVDVESDFMMYRSGIYQS--QTCSPLRVNHAVLAVGYGTQGGTDY 284 +L + R P +VA++ YR GI + CSP ++HAVL VGYG + + Sbjct: 118 QKLAAWLAKRGPISVAINAFG-MQFYRHGISRPLRPLCSPWLIDHAVLLVGYGQRSDVPF 176 Query: 285 WIVKNSWGTYWGERGYIRMARNRGNMCGIASLASLPMVA 323 W +KNSWGT WGE+GY + R G CG+ ++AS +V Sbjct: 177 WAIKNSWGTDWGEKGYYYLHRGSG-ACGVNTMASSAVVD 214 >4I04-A nrPDB Length = 323 Score = 221 bits (563), Expect = 3e-58, Method: Composition-based stats. Identities = 66/257 (25%), Positives = 100/257 (38%), Gaps = 42/257 (16%) Query: 99 VPYEANNRAVPDKID----WRESGYVTEVKDQGNCGSCWAFSTTGTMEGQYMK--NERTS 152 V + N +P D W + ++DQ CGS WAF M + + + Sbjct: 63 VDHNDWNVEIPSSFDSRKKWPRCKSIATIRDQSRCGSSWAFGAVEAMSDRSCIQSGGKQN 122 Query: 153 ISFSEQQLVDCSGPWGNNGCSGGLMENAYQYLKQFGLETESS---------YPYTAVEGQ 203 + S L+ C G GC GG++ A+ Y + G+ T SS YP+ E Sbjct: 123 VELSAVDLLSCCESCG-LGCEGGILGPAWDYWVKEGIVTGSSKENHAGCEPYPFPKCEHH 181 Query: 204 CRYNKQLGVAKVTG-----------YYTVH-------------SGSEVELKNLVGARRPA 239 + +K+ Y T + E ++ + P Sbjct: 182 TKGKYPPCGSKIYKTPRCKQTCQKKYKTPYTQDKHRGKSSYNVKNDEKAIQKEIMKYGPV 241 Query: 240 AVAVDVESDFMMYRSGIYQSQTCSPLRVNHAVLAVGYGTQGGTDYWIVKNSWGTYWGERG 299 V DF+ Y+SGIY+ T L HA+ +G+G + YW++ NSW WGE G Sbjct: 242 EAGFTVYEDFLNYKSGIYKHITGETLG-GHAIRIIGWGVENKAPYWLIANSWNEDWGENG 300 Query: 300 YIRMARNRGNMCGIASL 316 Y R+ R R + C I S Sbjct: 301 YFRIVRGR-DECSIESE 316 >5OGQ-A nrPDB Length = 254 Score = 217 bits (554), Expect = 4e-57, Method: Composition-based stats. Identities = 65/250 (26%), Positives = 98/250 (39%), Gaps = 42/250 (16%) Query: 106 RAVPDKID----WRESGYVTEVKDQGNCGSCWAFSTTGTMEGQYMK--NERTSISFSEQQ 159 +P D W + ++DQ CGSCWAF M + + ++ S Sbjct: 1 VEIPSSFDSRKKWPRCKSIATIRDQSRCGSCWAFGAVEAMSDRSCIQSGGKQNVELSAVD 60 Query: 160 LVDCSGPWGNNGCSGGLMENAYQYLKQFGLETESS---------YPYTAVEGQCRYNKQL 210 L+ C G GC GG++ A+ Y + G+ T SS YP+ E + Sbjct: 61 LLSCCESCG-LGCEGGILGPAWDYWVKEGIVTGSSKENHAGCEPYPFPKCEHHTKGKYPP 119 Query: 211 GVAKVTG-----------YYTVH-------------SGSEVELKNLVGARRPAAVAVDVE 246 +K+ Y T + E ++ + P V Sbjct: 120 CGSKIYKTPRCKQTCQKKYKTPYTQDKHRGKSSYNVKNDEKAIQKEIMKYGPVEAGFTVY 179 Query: 247 SDFMMYRSGIYQSQTCSPLRVNHAVLAVGYGTQGGTDYWIVKNSWGTYWGERGYIRMARN 306 DF+ Y+SGIY+ T L HA+ +G+G + YW++ NSW WGE GY R+ R Sbjct: 180 EDFLNYKSGIYKHITGETLG-GHAIRIIGWGVENKAPYWLIANSWNEDWGENGYFRIVRG 238 Query: 307 RGNMCGIASL 316 R + C I S Sbjct: 239 R-DECSIESE 247 >5VCN-A nrPDB Length = 222 Score = 217 bits (553), Expect = 5e-57, Method: Composition-based stats. Identities = 68/205 (33%), Positives = 100/205 (48%), Gaps = 7/205 (3%) Query: 105 NRAVPDKIDWRESGYVTEVKDQGNCGSCWAFSTTGTMEGQYMKNERTSISFSEQQLVDCS 164 N P +ID R+ VT ++ QG CGSCWAFS E Y+ S+ +EQ+LVDC+ Sbjct: 7 NGNAPAEIDLRQMRTVTPIRMQGGCGSCWAFSGVAATESAYLAYRNQSLDLAEQELVDCA 66 Query: 165 GPWGNNGCSGGLMENAYQYLKQFGLETESSYPYTAVEGQCRYNKQLGVAKVTGYYTVHSG 224 +GC G + +Y++ G+ ES Y Y A E CR ++ Y ++ Sbjct: 67 S---QHGCHGDTIPRGIEYIQHNGVVQESYYRYVAREQSCRRPNAQRFG-ISNYCQIYPP 122 Query: 225 SEVELKNLVGA-RRPAAVAVDVES-DFMMYRSGIYQSQTCSPLRVN-HAVLAVGYGTQGG 281 + +++ + AV + ++ D + G Q + + N HAV VGY G Sbjct: 123 NANKIREALAQTHSAIAVIIGIKDLDAFRHYDGRTIIQRDNGYQPNYHAVNIVGYSNAQG 182 Query: 282 TDYWIVKNSWGTYWGERGYIRMARN 306 DYWIV+NSW T WG+ GY A N Sbjct: 183 VDYWIVRNSWDTNWGDNGYGYFAAN 207 >4OEL-A nrPDB Length = 370 Score = 217 bits (552), Expect = 6e-57, Method: Composition-based stats. Identities = 65/243 (26%), Positives = 107/243 (44%), Gaps = 29/243 (11%) Query: 39 HRRNIWEK--NVKHIQEHNLRHDLGLVTYTLGLNQFTDMTFEEFKAKYLTEMSRASDILS 96 H +N EK N + +HN + + +T T+ E++ L +M R S S Sbjct: 131 HLKNSQEKYSNRLYKYDHNFVKAINAIQ-----KSWTATTYMEYETLTLGDMIRRSGGHS 185 Query: 97 HGVP----------YEANNRAVPDKIDWRES---GYVTEVKDQGNCGSCWAFSTTGTMEG 143 +P + +P DWR +V+ V++Q +CGSC++F++ G +E Sbjct: 186 RKIPRPKPAPLTAEIQQKILHLPTSWDWRNVHGINFVSPVRNQASCGSCYSFASMGMLEA 245 Query: 144 QYMK--NERTSISFSEQQLVDCSGPWGNNGCSGGLME-NAYQYLKQFGLETESSYPYTAV 200 + N + S Q++V CS GC GG A +Y + FGL E+ +PYT Sbjct: 246 RIRILTNNSQTPILSPQEVVSCS--QYAQGCEGGFPYLIAGKYAQDFGLVEEACFPYTGT 303 Query: 201 EGQCRYNKQLGVAKVTGYYTV----HSGSEVELKNLVGARRPAAVAVDVESDFMMYRSGI 256 + C+ + + Y+ V +E +K + P AVA +V DF+ Y+ GI Sbjct: 304 DSPCKMKEDCFRYYSSEYHYVGGFYGGCNEALMKLELVHHGPMAVAFEVYDDFLHYKKGI 363 Query: 257 YQS 259 Y Sbjct: 364 YHH 366 >2DCB-A nrPDB Length = 256 Score = 214 bits (545), Expect = 5e-56, Method: Composition-based stats. Identities = 70/259 (27%), Positives = 118/259 (45%), Gaps = 44/259 (16%) Query: 108 VPDKID----WRESGYVTEVKDQGNCGSCWAFSTTGTMEGQYMK--NERTSISFSEQQLV 161 +P+ D W + E++DQG+CGSCWAF + + N R ++ S + ++ Sbjct: 1 LPESFDAREQWPNCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHSNGRVNVEVSAEDML 60 Query: 162 DCSGPWGNNGCSGGLMENAYQYLKQFGLETESSY----------------------PYTA 199 C G +GC+GG A+ + + GL + Y P Sbjct: 61 TCCGGECGDGCNGGFPSGAWNFWTKKGLVSGGLYNSHVGCRPYSIPPCEHHVNGSRPPCT 120 Query: 200 VEG---QCRYNKQLGVAKV--------TGYYTVHSGSEVELKNLVGARRPAAVAVDVESD 248 EG +C + G + Y+V + +E E+ + P A V SD Sbjct: 121 GEGDTPKCSKTCEPGYSPSYKEDKHFGCSSYSV-ANNEKEIMAEIYKNGPVEGAFSVYSD 179 Query: 249 FMMYRSGIYQSQTCSPLRVNHAVLAVGYGTQGGTDYWIVKNSWGTYWGERGYIRMARNRG 308 F++Y+SG+YQ + + HA+ +G+G + GT YW+V NSW T WG+ G+ ++ R + Sbjct: 180 FLLYKSGVYQHVSG-EIMGGHAIRILGWGVENGTPYWLVGNSWNTDWGDNGFFKILRGQ- 237 Query: 309 NMCGIAS--LASLPMVARF 325 + CGI S +A +P ++ Sbjct: 238 DHCGIESEIVAGMPCTHQY 256 >5FPW-A nrPDB Length = 321 Score = 208 bits (529), Expect = 3e-54, Method: Composition-based stats. Identities = 65/285 (22%), Positives = 102/285 (35%), Gaps = 34/285 (11%) Query: 71 QFTDMTFEEFKAKYLTEMSRASDILSHGVPYEANNRAVPDKID----WRESGYVTEVKDQ 126 + ++TF E K + + S + E +P+ D W + E+ DQ Sbjct: 38 KMQNITFAEAKRLTGAWIQKTSSLPPVRFTEEQLRTELPESFDSAEKWPNCPTIREIADQ 97 Query: 127 GNCGSCWAFSTTGTMEGQYMKNER-TSISFSEQQLVDCSGPWGNNGCSGGLMENAYQYLK 185 C + WA ST + +Y + S L+ GC GG A++Y Sbjct: 98 SACRASWAVSTASVISDRYCTVGGVQQLRISAAHLLS-CCKQCGGGCKGGFPGFAWRYYV 156 Query: 186 QFGLETESSYPYTAVE--------------------GQCRYNKQLGVAKVTGYY----TV 221 ++G+ + PY +C+ + Y + Sbjct: 157 EYGIASSYCQPYPFPHCEHRGAQGNKTPCSKYNFDTPKCQATCTDKSIPLVKYRGSATYL 216 Query: 222 HSGSEVELKNLVGARRPAAVAVDVESDFMMYRSGIYQSQTCSPLRVNHAVLAVGYGTQGG 281 E + K + P V +D Y+SG+Y+ L AV VG+G G Sbjct: 217 LLHGEEDYKRELYFNGPFVAVFYVYTDLFAYKSGVYRHVDGDFLG-GTAVKVVGWGKLNG 275 Query: 282 TDYWIVKNSWGTYWGERGYIRMARNRGNMCGIASL--ASLPMVAR 324 T YW V N+W T WG GY+ + R N C I L A P ++ Sbjct: 276 TPYWKVANTWDTDWGMDGYLLILRG-NNECNIEHLGFAGTPETSQ 319 >1DEU-A nrPDB Length = 277 Score = 189 bits (479), Expect = 2e-48, Method: Composition-based stats. Identities = 63/225 (28%), Positives = 94/225 (41%), Gaps = 28/225 (12%) Query: 106 RAVPDKIDWRES---GYVTEVKDQ---GNCGSCWAFSTTGTMEGQYMKNE---RTSISFS 156 +P DWR Y + ++Q CGSCWA ++T M + S S Sbjct: 34 ADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLS 93 Query: 157 EQQLVDCSGPWGNNG-CSGGLMENAYQYLKQFGLETESSYPYTAVEGQCRYNKQLGVAK- 214 Q ++DC GN G C GG + + Y Q G+ E+ Y A + +C Q G Sbjct: 94 VQNVIDC----GNAGSCEGGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNE 149 Query: 215 ------VTGYYTVHSGS------EVELKNLVGARRPAAVAVDVESDFMMYRSGIYQSQTC 262 + Y G ++ + A P + + Y GIY ++ Sbjct: 150 FKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIY-AEYQ 208 Query: 263 SPLRVNHAVLAVGYGTQGGTDYWIVKNSWGTYWGERGYIRMARNR 307 +NH V G+G GT+YWIV+NSWG WGERG++R+ + Sbjct: 209 DTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWGERGWLRIVTST 253 >1EF7-A nrPDB Length = 242 Score = 185 bits (471), Expect = 2e-47, Method: Composition-based stats. Identities = 63/223 (28%), Positives = 94/223 (42%), Gaps = 28/223 (12%) Query: 108 VPDKIDWRES---GYVTEVKDQ---GNCGSCWAFSTTGTMEGQYMKNE---RTSISFSEQ 158 +P DWR Y + ++Q CGSCWA ++T M + S S Q Sbjct: 1 LPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQ 60 Query: 159 QLVDCSGPWGNNG-CSGGLMENAYQYLKQFGLETESSYPYTAVEGQCRYNKQLGVAK--- 214 ++DC GN G C GG + + Y Q G+ E+ Y A + +C Q G Sbjct: 61 NVIDC----GNAGSCEGGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFK 116 Query: 215 ----VTGYYTVHSGS------EVELKNLVGARRPAAVAVDVESDFMMYRSGIYQSQTCSP 264 + Y G ++ + A P + + Y GIY ++ Sbjct: 117 ECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIY-AEYQDT 175 Query: 265 LRVNHAVLAVGYGTQGGTDYWIVKNSWGTYWGERGYIRMARNR 307 +NH V G+G GT+YWIV+NSWG WGERG++R+ + Sbjct: 176 TYINHVVSVAGWGISDGTEYWIVRNSWGEPWGERGWLRIVTST 218 >1CSB-B nrPDB Length = 205 Score = 174 bits (441), Expect = 4e-44, Method: Composition-based stats. Identities = 59/207 (28%), Positives = 92/207 (44%), Gaps = 36/207 (17%) Query: 151 TSISFSEQQLVDCSGPWGNNGCSGGLMENAYQYLKQFGLETESSY--------------- 195 S+ S + L+ C G +GC+GG A+ + + GL + Y Sbjct: 1 VSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCE 60 Query: 196 -------PYTAVEG---QCR------YNKQLGVAKVTGYYTVH-SGSEVELKNLVGARRP 238 P EG +C Y+ K GY + S SE ++ + P Sbjct: 61 HHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGP 120 Query: 239 AAVAVDVESDFMMYRSGIYQSQTCSPLRVNHAVLAVGYGTQGGTDYWIVKNSWGTYWGER 298 A V SDF++Y+SG+YQ T + HA+ +G+G + GT YW+V NSW T WG+ Sbjct: 121 VEGAFSVYSDFLLYKSGVYQHVTG-EMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDN 179 Query: 299 GYIRMARNRGNMCGIAS--LASLPMVA 323 G+ ++ R + + CGI S +A +P Sbjct: 180 GFFKILRGQ-DHCGIESEVVAGIPRTD 205 >4CDF-B nrPDB Length = 166 Score = 172 bits (437), Expect = 1e-43, Method: Composition-based stats. Identities = 49/164 (29%), Positives = 79/164 (48%), Gaps = 12/164 (7%) Query: 106 RAVPDKIDWRES---GYVTEVKDQGNCGSCWAFSTTGTMEGQYMK--NERTSISFSEQQL 160 +P DWR +V+ V++Q +CGSC++F++ G +E + N + S Q++ Sbjct: 1 LHLPTSWDWRNVHGINFVSPVRNQASCGSCYSFASMGMLEARIRILTNNSQTPILSPQEV 60 Query: 161 VDCSGPWGNNGCSGGLME-NAYQYLKQFGLETESSYPYTAVEGQCRYNKQLGVAKVTGYY 219 V CS GC GG A +Y + FGL E+ +PYT + C+ + + Y+ Sbjct: 61 VSCS--QYAQGCEGGFPYLIAGKYAQDFGLVEEACFPYTGTDSPCKMKEDCFRYYSSEYH 118 Query: 220 TV----HSGSEVELKNLVGARRPAAVAVDVESDFMMYRSGIYQS 259 V +E +K + P AVA +V DF+ Y+ GIY Sbjct: 119 YVGGFYGGCNEALMKLELVHHGPMAVAFEVYDDFLHYKKGIYHH 162 >5I4H-A nrPDB Length = 106 Score = 171 bits (434), Expect = 3e-43, Method: Composition-based stats. Identities = 60/106 (56%), Positives = 73/106 (68%), Gaps = 1/106 (0%) Query: 107 AVPDKIDWRESGYVTEVKDQGNCGSCWAFSTTGTMEGQYMKNERTSISFSEQQLVDCSGP 166 P +DWRE GYVT VK+QG CGS WAFS TG +EGQ + IS SEQ LVDCSGP Sbjct: 1 EAPRSVDWREKGYVTPVKNQGQCGSSWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGP 60 Query: 167 WGNNGCSGGLMENAYQYLK-QFGLETESSYPYTAVEGQCRYNKQLG 211 GN GC+GGLM+ A+QY++ GL++E SYPY A E C+YN + Sbjct: 61 QGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYS 106 >3CH2-X nrPDB Length = 265 Score = 153 bits (387), Expect = 9e-38, Method: Composition-based stats. Identities = 55/224 (24%), Positives = 87/224 (38%), Gaps = 34/224 (15%) Query: 122 EVKDQGNCGSCWAFSTTGTMEGQYMKNERTSISFSEQQLVDCSGPWGNNGCSGGLMENAY 181 +V+DQGNC + W F++ +E S + +C + C G + Sbjct: 23 QVEDQGNCDTSWIFASKYHLETIRCMKGYEPTKISALYVANCYKGEHKDRCDEGSSPMEF 82 Query: 182 -QYLKQFG-LETESSYPYTAVE------------------GQCRYNKQLGVAKVTGYYTV 221 Q ++ +G L ES+YPY V+ G+ +NK + YT Sbjct: 83 LQIIEDYGFLPAESNYPYNYVKVGEQCPKVEDHWMNLWDNGKILHNKNEPNSLDGKGYTA 142 Query: 222 HSGSE--------VELKNLVGARRPAAVAVDVESDFMMYR-SGIYQSQTCSPLRVNHAVL 272 + V++ + + +A + M Y SG C +HAV Sbjct: 143 YESERFHDNMDAFVKIIKTEVMNKGSVIAYIKAENVMGYEFSGKKVQNLCGDDTADHAVN 202 Query: 273 AVGYGTQGGTD-----YWIVKNSWGTYWGERGYIRMARNRGNMC 311 VGYG ++ YWIV+NSWG YWG+ GY ++ C Sbjct: 203 IVGYGNYVNSEGEKKSYWIVRNSWGPYWGDEGYFKVDMYGPTHC 246 >1SP4-B nrPDB Length = 205 Score = 142 bits (358), Expect = 2e-34, Method: Composition-based stats. Identities = 55/208 (26%), Positives = 93/208 (44%), Gaps = 38/208 (18%) Query: 150 RTSISFSEQQLVDCSGPWGNNGCSGGLMENAYQYLKQFGLETESSY-------------- 195 R ++ S + ++ C G +GC+GG A+ + + GL + Y Sbjct: 1 RVNVEVSAEDMLTCCGGECGDGCNGGFPSGAWNFWTKKGLVSGGLYNSHVGCRPYSIPPC 60 Query: 196 --------PYTAVEG---QCRYNKQLGVAKV--------TGYYTVHSGSEVELKNLVGAR 236 P EG +C + G + Y+V + +E E+ + Sbjct: 61 EHHVNGSRPPCTGEGDTPKCNKTCEPGYSPSYKEDKHFGCSSYSV-ANNEKEIMAEIYKN 119 Query: 237 RPAAVAVDVESDFMMYRSGIYQSQTCSPLRVNHAVLAVGYGTQGGTDYWIVKNSWGTYWG 296 P A V SDF++Y+SG+YQ + + HA+ +G+G + GT YW+V NSW T WG Sbjct: 120 GPVEGAFSVYSDFLLYKSGVYQHVSG-EIMGGHAIRILGWGVENGTPYWLVGNSWNTDWG 178 Query: 297 ERGYIRMARNRGNMCGIAS--LASLPMV 322 + G+ ++ R + + CGI S +A +P Sbjct: 179 DNGFFKILRGQ-DHCGIESEIVAGMPCT 205 >5I4H-B nrPDB Length = 112 Score = 140 bits (354), Expect = 6e-34, Method: Composition-based stats. Identities = 47/113 (41%), Positives = 61/113 (53%), Gaps = 6/113 (5%) Query: 215 VTGYYTVHSGSEVELKNLVGARRPAAVAVDV-ESDFMMYRSGIYQSQTCSPLRVNHAVLA 273 G+ + E L V P +VA+D F+ Y+ GIY CS ++H VL Sbjct: 1 DAGFVDIPK-QEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLV 59 Query: 274 VGYGTQ----GGTDYWIVKNSWGTYWGERGYIRMARNRGNMCGIASLASLPMV 322 VGYG + YW+VKNSWG WG GY++MA++R N CGIAS AS P V Sbjct: 60 VGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV 112 >2L95-A nrPDB Length = 80 Score = 86.2 bits (212), Expect = 2e-17, Method: Composition-based stats. Identities = 23/73 (31%), Positives = 43/73 (58%) Query: 17 NDDLWHQWKRMYNKEYNGADDQHRRNIWEKNVKHIQEHNLRHDLGLVTYTLGLNQFTDMT 76 +D+ W ++K ++K Y +D RR I+ ++ I+EHN + + G VT+ +G+N D+T Sbjct: 6 SDEEWVEYKSKFDKNYEAEEDLMRRRIYAESKARIEEHNRKFEKGEVTWKMGINHLADLT 65 Query: 77 FEEFKAKYLTEMS 89 EEF + ++ Sbjct: 66 PEEFAQRSGKKVP 78 >4OEM-B nrPDB Length = 70 Score = 82.4 bits (202), Expect = 2e-16, Method: Composition-based stats. Identities = 33/53 (62%), Positives = 36/53 (67%), Gaps = 3/53 (5%) Query: 267 VNHAVLAVGYGTQG--GTDYWIVKNSWGTYWGERGYIRMARNRGNMCGIASLA 317 NHAVL VGYGT G DYWIVKNSWGT WGE GY R+ R + C I S+A Sbjct: 9 TNHAVLLVGYGTDSASGMDYWIVKNSWGTGWGENGYFRIRRGT-DECAIESIA 60 >4CI7-A nrPDB Length = 470 Score = 65.4 bits (158), Expect = 4e-11, Method: Composition-based stats. Identities = 46/215 (21%), Positives = 72/215 (33%), Gaps = 37/215 (17%) Query: 118 GYVTEVKDQGNCGSCWAFSTTGTMEGQYMKNERTSISFSEQQLVDCSGPWGNNGCSGGLM 177 G T K+QG+ + W+FS T+E + SE+ L W G G + Sbjct: 75 GLTTPAKNQGSLNTAWSFSGMSTLEAYLKLKGYGTYDLSEEHL----RWWATGGKYGWNL 130 Query: 178 EN--------AYQYLKQ-FGLETESSYPY------TAVEGQCRYNKQLGVAKVTGYYTVH 222 ++ A YL G + E PY + VT ++ Sbjct: 131 DDMSGSSNVTAIGYLTAWAGPKLEKDIPYNLKSEAQGATKPSNMDTAPTQFNVTDVVRLN 190 Query: 223 SGSEVELKNLVGARRPAAVAVDVESDFMMYRSGIYQSQTCSPLR--VNHAVLAVGYGTQG 280 E +KN + S + Y C+ R +NHAV VG+ Sbjct: 191 KDKET-VKNAIMQYGSVTSGYAHYSTYFNKDETAY---NCTNKRAPLNHAVAIVGWDDNY 246 Query: 281 GTD------------YWIVKNSWGTYWGERGYIRM 303 D W+VK+SWG + +G+ + Sbjct: 247 SKDNFASDVKPESNGAWLVKSSWGEFNSMKGFFWI 281 >4D59-A nrPDB Length = 406 Score = 64.6 bits (156), Expect = 5e-11, Method: Composition-based stats. Identities = 46/215 (21%), Positives = 72/215 (33%), Gaps = 37/215 (17%) Query: 118 GYVTEVKDQGNCGSCWAFSTTGTMEGQYMKNERTSISFSEQQLVDCSGPWGNNGCSGGLM 177 G T K+QG+ + W+FS T+E + SE+ L W G G + Sbjct: 11 GLTTPAKNQGSLNTAWSFSGMSTLEAYLKLKGYGTYDLSEEHL----RWWATGGKYGWNL 66 Query: 178 EN--------AYQYLKQ-FGLETESSYPY------TAVEGQCRYNKQLGVAKVTGYYTVH 222 ++ A YL G + E PY + VT ++ Sbjct: 67 DDMSGSSNVTAIGYLTAWAGPKLEKDIPYNLKSEAQGATKPSNMDTAPTQFNVTDVVRLN 126 Query: 223 SGSEVELKNLVGARRPAAVAVDVESDFMMYRSGIYQSQTCSPLR--VNHAVLAVGYGTQG 280 E +KN + S + Y C+ R +NHAV VG+ Sbjct: 127 KDKET-VKNAIMQYGSVTSGYAHYSTYFNKDETAY---NCTNKRAPLNHAVAIVGWDDNY 182 Query: 281 GTD------------YWIVKNSWGTYWGERGYIRM 303 D W+VK+SWG + +G+ + Sbjct: 183 SKDNFASDVKPESNGAWLVKSSWGEFNSMKGFFWI 217 >3OIS-A nrPDB Length = 291 Score = 63.1 bits (152), Expect = 1e-10, Method: Composition-based stats. Identities = 53/231 (22%), Positives = 86/231 (37%), Gaps = 37/231 (16%) Query: 100 PYEANNRAVPDKIDWRESGYVTE---VKDQGNCGSCWAFSTTGTMEGQYMKNERTSISFS 156 P ++ A+P K+D +T V DQG GSC A + ++ +++ S F Sbjct: 49 PEKSVIAALPPKVD------LTPPFQVYDQGRIGSCTANALAAAIQ-FERIHDKQSPEFI 101 Query: 157 EQQLVDCSGPWGNNGC----SGGLMENAYQYLKQFGLETESSYPY--------------- 197 +L G SG ++ + + L + G+ E +PY Sbjct: 102 PSRLFIYYNERKIEGHVNYDSGAMIRDGIKVLHKLGVCPEKEWPYGDTPADPRTEEFPPG 161 Query: 198 --TAVEGQCRYNKQLGVAKVTGYYTVHSGSEVELKNLVGARRPAAVAVDVESDFMMYRS- 254 + + + K K+T Y V + LK + P V + ++ S Sbjct: 162 APASKKPSDQCYKDAQNYKITEYSRV-AQDIDHLKACLAVGSPFVFGFSVYNSWVGNNSL 220 Query: 255 --GIYQSQTCSPLRVNHAVLAVGYGTQGGTDYWIVKNSWGTYWGERGYIRM 303 I L HAVL VGY + ++ ++NSWG GE GY M Sbjct: 221 PVRIPLPTKNDTLEGGHAVLCVGYDDE--IRHFRIRNSWGNNVGEDGYFWM 269 >4K7C-A nrPDB Length = 446 Score = 42.7 bits (99), Expect = 2e-04, Method: Composition-based stats. Identities = 14/42 (33%), Positives = 19/42 (45%), Gaps = 1/42 (2%) Query: 261 TCSPLRVNHAVLAVGYGTQGGTDY-WIVKNSWGTYWGERGYI 301 + HA++ G G W V+NSWG GE+GY Sbjct: 356 DYGESLMTHAMVLTGVDLVDGKPTKWKVENSWGEKVGEKGYF 397 >5WDK-A nrPDB Length = 401 Score = 38.5 bits (88), Expect = 0.004, Method: Composition-based stats. Identities = 20/84 (23%), Positives = 34/84 (40%), Gaps = 10/84 (11%) Query: 120 VTEVKDQGNCGSCWAFSTTGTMEGQYMKNERTSISFSEQ------QLVDCSGPWGNNG-- 171 +T VK+Q G+CW +S+ +E + ++ + SE L +G Sbjct: 40 ITSVKNQNRAGTCWCYSSYSFLESELLRMGKGEYDLSEMFTVYNTYLDRADAAVRTHGDV 99 Query: 172 --CSGGLMENAYQYLKQFGLETES 193 GG +A ++ FGL E Sbjct: 100 SFSQGGSFYDALYGMETFGLVPEE 123 Score = 35.4 bits (80), Expect = 0.035, Method: Composition-based stats. Identities = 11/28 (39%), Positives = 16/28 (57%), Gaps = 1/28 (3%) Query: 268 NHAVLAVGYGTQG-GTDYWIVKNSWGTY 294 +H + G G +Y++VKNSWGT Sbjct: 335 DHGMQIYGIAKDQEGNEYYMVKNSWGTN 362 >2QGM-A nrPDB Length = 445 Score = 36.1 bits (82), Expect = 0.021, Method: Composition-based stats. Identities = 37/199 (18%), Positives = 69/199 (34%), Gaps = 42/199 (21%) Query: 23 QWKRMYNKEYNGADDQH---------RRNIWEKNVKHIQEHN-------LRHDLGLVTYT 66 +W + YN + + + + K + +++ H + L ++T Sbjct: 150 EWMKDYNADPSNKKKIQFIGLDLKALDQGSFNKVIDYVRLHRPDLLAEVEENYKELSSFT 209 Query: 67 LGLNQFTDMTFEEFKAKYLTEMSRASDILSHGVPYEANNRAVPDKIDWRESGYVTEVKDQ 126 + ++ +T + K K+ R + +L +AN +P + Y+ Sbjct: 210 GSIQEYMKLTP-KLKEKFKANAERVARLLK-DENEQANTEIIPSE-------YI------ 254 Query: 127 GNCGSCWAFSTTGTME---GQYMKNERTSI-SFSEQQLVDCSGPWGNNGCSGGLMENAYQ 182 WA +T +E + N+ SI EQ L D W G M A+ Sbjct: 255 ------WAKATASAIEKFTTMLLPNDYPSIIKLHEQYLAD-HAMWAQETFGGKTMVWAHN 307 Query: 183 YLKQFGLETESSYPYTAVE 201 G+ E YPY A + Sbjct: 308 IHIAKGIIDEKLYPYVAGQ 326 >2CB5-A nrPDB Length = 453 Score = 33.8 bits (76), Expect = 0.091, Method: Composition-based stats. Identities = 14/47 (29%), Positives = 20/47 (42%), Gaps = 4/47 (8%) Query: 261 TCSPLRVNHAVLAVGYGTQGGTD----YWIVKNSWGTYWGERGYIRM 303 T + HA+ + D W V+NSWG G +GY+ M Sbjct: 363 TFGESLMTHAMTFTAVSEKDDQDGAFTKWRVENSWGEDHGHKGYLCM 409 >5L22-B nrPDB Length = 572 Score = 31.1 bits (69), Expect = 0.66, Method: Composition-based stats. Identities = 12/47 (25%), Positives = 23/47 (48%) Query: 5 ILAVLTVGVLGSNDDLWHQWKRMYNKEYNGADDQHRRNIWEKNVKHI 51 +L V LG ++L+ +W Y+K + ++ RN + N+ I Sbjct: 201 LLNAEVVEALGMRNNLYKKWMNFYSKHLSAFEEATDRNNFLSNLTRI 247 >1QHM-A nrPDB Length = 624 Score = 31.1 bits (69), Expect = 0.67, Method: Composition-based stats. Identities = 18/88 (20%), Positives = 28/88 (31%), Gaps = 5/88 (5%) Query: 78 EEFKAKYLTEMSRASDILSHGVPYEANNRAVPDKIDWRESGYVTEVKDQGNCGSCWAFST 137 EE ++ +G + I W GY+ VK Q G+ +F Sbjct: 221 EEIAEQHRALGQMKEMAAKYGYDISGPATNAQEAIQWTYFGYLAAVKSQN--GAAMSFGR 278 Query: 138 TGTMEGQYM---KNERTSISFSEQQLVD 162 T T Y+ Q++VD Sbjct: 279 TSTFLDVYIERDLKAGKITEQEAQEMVD 306 >1H18-A nrPDB Length = 759 Score = 31.1 bits (69), Expect = 0.67, Method: Composition-based stats. Identities = 18/88 (20%), Positives = 28/88 (31%), Gaps = 5/88 (5%) Query: 78 EEFKAKYLTEMSRASDILSHGVPYEANNRAVPDKIDWRESGYVTEVKDQGNCGSCWAFST 137 EE ++ +G + I W GY+ VK Q G+ +F Sbjct: 221 EEIAEQHRALGQMKEMAAKYGYDISGPATNAQEAIQWTYFGYLAAVKSQN--GAAMSFGR 278 Query: 138 TGTMEGQYM---KNERTSISFSEQQLVD 162 T T Y+ Q++VD Sbjct: 279 TSTFLDVYIERDLKAGKITEQEAQEMVD 306 >1A6R-A nrPDB Length = 471 Score = 30.0 bits (66), Expect = 1.3, Method: Composition-based stats. Identities = 18/98 (18%), Positives = 32/98 (32%), Gaps = 19/98 (19%) Query: 68 GLNQFTDMTFEEFKAKYLTEMSRASDILSHGVPYEANNRAVPDKIDWRESGYV-----TE 122 +N + +EF++ +++ + N + K D R V T Sbjct: 26 KINSW----NKEFQSDLTHQLATTVLKNYNADDALLNKTRL-QKQDNRVFNTVVSTDSTP 80 Query: 123 VKDQGNCGSCWAFSTTGTMEGQYMKNERTSISFSEQQL 160 V +Q + G W F+ T + SE L Sbjct: 81 VTNQKSSGRAWLFAATNQL---------RLNVLSELNL 109 >2Z51-A nrPDB Length = 154 Score = 30.0 bits (66), Expect = 1.5, Method: Composition-based stats. Identities = 10/15 (66%), Positives = 10/15 (66%) Query: 118 GYVTEVKDQGNCGSC 132 G V VK QG CGSC Sbjct: 34 GNVVRVKLQGACGSC 48 >1V9N-A nrPDB Length = 360 Score = 28.8 bits (63), Expect = 3.0, Method: Composition-based stats. Identities = 18/78 (23%), Positives = 30/78 (38%), Gaps = 12/78 (15%) Query: 256 IYQSQTCSPLRVNHAV-LAVGY---------GTQGGTDYWIVKNSWGTYWGERGYIRMAR 305 I + + + + + + VGY G I +NS ++G GY + Sbjct: 81 IREGPSYALIDGDEGLGQVVGYRSMKLAIKKAKDTGIGIVIARNS--NHYGIAGYYALMA 138 Query: 306 NRGNMCGIASLASLPMVA 323 M GI+ S P+VA Sbjct: 139 AEEGMIGISMTNSRPLVA 156 >1L9N-A nrPDB Length = 692 Score = 28.8 bits (63), Expect = 3.1, Method: Composition-based stats. Identities = 11/38 (28%), Positives = 17/38 (44%), Gaps = 13/38 (34%) Query: 109 PDKID--------WRESGYVTEVKDQGNCGSCWAFSTT 138 P D W++SG ++ V+ G CW F+ T Sbjct: 246 PRSWDGSVEILKNWKKSG-LSPVRY----GQCWVFAGT 278 >3B55-A nrPDB Length = 451 Score = 28.8 bits (63), Expect = 3.1, Method: Composition-based stats. Identities = 18/85 (21%), Positives = 33/85 (38%), Gaps = 11/85 (12%) Query: 42 NIWEKNVKHIQEHN-------LRHDLGLVTYTLGLNQFTDMTFEEFKAKYLTEMSRASDI 94 N++ +++I+ +N GL+ T +N F +T EE K KY+ + S + Sbjct: 179 NVYNNIIEYIKANNSKLLPRVEEKIKGLIPVTKDMNTFESLTKEE-KEKYVLDAKTISAL 237 Query: 95 LSHGVPYEANNRAVPDKIDWRESGY 119 L Y + W + Sbjct: 238 LEENKSYLNGKS---KEFAWIKQNA 259 >1G0D-A nrPDB Length = 695 Score = 28.8 bits (63), Expect = 3.2, Method: Composition-based stats. Identities = 13/40 (32%), Positives = 17/40 (42%), Gaps = 6/40 (15%) Query: 100 PYEANNRAVPDKIDWRESGYVTEVKDQGNCGSCWAFSTTG 139 PY +VP W ++G V VK G CW F+ Sbjct: 246 PYRW-TGSVPILQQWSKAG-VRPVKY----GQCWVFAAVA 279 >2G7H-A nrPDB Length = 167 Score = 28.4 bits (62), Expect = 3.9, Method: Composition-based stats. Identities = 15/94 (15%), Positives = 36/94 (38%), Gaps = 6/94 (6%) Query: 22 HQWKRMYNKEYNGADDQHRRNIWEKNVKHIQEHNLRHDLGLVTYTLGLNQFT----DMTF 77 + M + + +D+H + + E + + L++Y L + +FT D+ Sbjct: 30 EIFNFMDGEVVSNPEDEHLKVAEIILKLYFAEIDDKKVRELISYKLEVPEFTKKVLDIVK 89 Query: 78 E-EF-KAKYLTEMSRASDILSHGVPYEANNRAVP 109 + EF K ++++ + V +P Sbjct: 90 DIEFGKTLTYGDIAKKLNTSPRAVGMALKRNPLP 123 >4G6U-A nrPDB Length = 292 Score = 28.4 bits (62), Expect = 4.0, Method: Composition-based stats. Identities = 16/76 (21%), Positives = 31/76 (40%) Query: 15 GSNDDLWHQWKRMYNKEYNGADDQHRRNIWEKNVKHIQEHNLRHDLGLVTYTLGLNQFTD 74 G+ D+ +W+++ +++ D + + N E V + +D+ LG Sbjct: 21 GNCQDIIDKWEKISDEQSAEIDQKLKDNPLEAQVIDKEVAKGGYDMTQRPGWLGNIGVEV 80 Query: 75 MTFEEFKAKYLTEMSR 90 MT +E KA R Sbjct: 81 MTSDEAKAYVQKWNGR 96 >1UT9-A nrPDB Length = 609 Score = 28.4 bits (62), Expect = 4.1, Method: Composition-based stats. Identities = 12/47 (25%), Positives = 17/47 (36%), Gaps = 2/47 (4%) Query: 176 LMENAYQYLKQFGLETESSYPYTAVEGQCRYNKQLGVAKVTGYYTVH 222 A+ Y K+ G+ E PY E R +G+ G V Sbjct: 106 YDALAFFYHKRSGIPIEM--PYAGGEQWTRPAGHIGIEPNKGDTNVP 150 >2HCZ-X nrPDB Length = 245 Score = 28.4 bits (62), Expect = 4.3, Method: Composition-based stats. Identities = 10/30 (33%), Positives = 12/30 (40%) Query: 104 NNRAVPDKIDWRESGYVTEVKDQGNCGSCW 133 N +P G V KD CGSC+ Sbjct: 45 KNVNLPPYSGMTACGNVPIFKDGKGCGSCY 74 >2JNV-A nrPDB Length = 91 Score = 27.7 bits (60), Expect = 7.3, Method: Composition-based stats. Identities = 9/15 (60%), Positives = 10/15 (66%) Query: 118 GYVTEVKDQGNCGSC 132 G V +K QG CGSC Sbjct: 35 GNVVRLKLQGACGSC 49 >3S9V-A nrPDB Length = 785 Score = 27.3 bits (59), Expect = 8.7, Method: Composition-based stats. Identities = 12/85 (14%), Positives = 32/85 (37%), Gaps = 4/85 (4%) Query: 17 NDDLWHQWKRMYNKEYNGADDQHRRNIWEKNVKHIQEHNLRHDLGLVTYTLG--LNQFTD 74 N D + +W + K G + + W K++ ++ + + G LG + Sbjct: 400 NVDAFDKW--AFKKNIRGEVEYALKYPWHKSMPRLEARSYIENYGPDDVWLGKTVYMMPY 457 Query: 75 MTFEEFKAKYLTEMSRASDILSHGV 99 ++ E++ + ++ I + Sbjct: 458 ISNEKYLELAKLDFNKVQSIHQTEL 482 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.311 0.139 0.455 Lambda K H 0.267 0.0429 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 13,714,920 Number of Sequences: 36641 Number of extensions: 570218 Number of successful extensions: 2269 Number of sequences better than 10.0: 98 Number of HSP's better than 10.0 without gapping: 172 Number of HSP's successfully gapped in prelim test: 19 Number of HSP's that attempted gapping in prelim test: 1458 Number of HSP's gapped (non-prelim): 219 length of query: 326 length of database: 10,336,785 effective HSP length: 97 effective length of query: 229 effective length of database: 6,782,608 effective search space: 1553217232 effective search space used: 1553217232 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 59 (27.3 bits)