BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q16853 (763 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 1US1-A nrPDB 1578 0.0 2PNC-A nrPDB 1274 0.0 3K5T-A nrPDB 522 e-148 3PGB-A nrPDB 276 2e-74 1RKY-A nrPDB 218 1e-56 1D6Z-A nrPDB 136 3e-32 2CG0-A nrPDB 123 3e-28 3LOY-A nrPDB 123 3e-28 1KSI-A nrPDB 110 3e-24 3NBJ-A nrPDB 100 4e-21 >1US1-A nrPDB Length = 763 Score = 1578 bits (4085), Expect = 0.0, Method: Compositional matrix adjust. Identities = 763/763 (100%), Positives = 763/763 (100%) Query: 1 MNQKTILVLLILAVITIFALVCVLLVGRGGDGGEPSQLPHCPSVSPSAQPWTHPGQSQLF 60 MNQKTILVLLILAVITIFALVCVLLVGRGGDGGEPSQLPHCPSVSPSAQPWTHPGQSQLF Sbjct: 1 MNQKTILVLLILAVITIFALVCVLLVGRGGDGGEPSQLPHCPSVSPSAQPWTHPGQSQLF 60 Query: 61 ADLSREELTAVMRFLTQRLGPGLVDAAQARPSDNCVFSVELQLPPKAAALAHLDRGSPPP 120 ADLSREELTAVMRFLTQRLGPGLVDAAQARPSDNCVFSVELQLPPKAAALAHLDRGSPPP Sbjct: 61 ADLSREELTAVMRFLTQRLGPGLVDAAQARPSDNCVFSVELQLPPKAAALAHLDRGSPPP 120 Query: 121 AREALAIVFFGRQPQPNVSELVVGPLPHPSYMRDVTVERHGGPLPYHRRPVLFQEYLDID 180 AREALAIVFFGRQPQPNVSELVVGPLPHPSYMRDVTVERHGGPLPYHRRPVLFQEYLDID Sbjct: 121 AREALAIVFFGRQPQPNVSELVVGPLPHPSYMRDVTVERHGGPLPYHRRPVLFQEYLDID 180 Query: 181 QMIFNRELPQASGLLHHCCFYKHRGRNLVTMTTAPRGLQSGDRATWFGLYYNISGAGFFL 240 QMIFNRELPQASGLLHHCCFYKHRGRNLVTMTTAPRGLQSGDRATWFGLYYNISGAGFFL Sbjct: 181 QMIFNRELPQASGLLHHCCFYKHRGRNLVTMTTAPRGLQSGDRATWFGLYYNISGAGFFL 240 Query: 241 HHVGLELLVNHKALDPARWTIQKVFYQGRYYDSLAQLEAQFEAGLVNVVLIPDNGTGGSW 300 HHVGLELLVNHKALDPARWTIQKVFYQGRYYDSLAQLEAQFEAGLVNVVLIPDNGTGGSW Sbjct: 241 HHVGLELLVNHKALDPARWTIQKVFYQGRYYDSLAQLEAQFEAGLVNVVLIPDNGTGGSW 300 Query: 301 SLKSPVPPGPAPPLQFYPQGPRFSVQGSRVASSLWTFSFGLGAFSGPRIFDVRFQGERLV 360 SLKSPVPPGPAPPLQFYPQGPRFSVQGSRVASSLWTFSFGLGAFSGPRIFDVRFQGERLV Sbjct: 301 SLKSPVPPGPAPPLQFYPQGPRFSVQGSRVASSLWTFSFGLGAFSGPRIFDVRFQGERLV 360 Query: 361 YEISLQEALAIYGGNSPAAMTTRYVDGGFGMGKYTTPLTRGVDCPYLATYVDWHFLLESQ 420 YEISLQEALAIYGGNSPAAMTTRYVDGGFGMGKYTTPLTRGVDCPYLATYVDWHFLLESQ Sbjct: 361 YEISLQEALAIYGGNSPAAMTTRYVDGGFGMGKYTTPLTRGVDCPYLATYVDWHFLLESQ 420 Query: 421 APKTIRDAFCVFEQNQGLPLRRHHSDLYSHYFGGLAETVLVVRSMSTLLNYDYVWDTVFH 480 APKTIRDAFCVFEQNQGLPLRRHHSDLYSHYFGGLAETVLVVRSMSTLLNYDYVWDTVFH Sbjct: 421 APKTIRDAFCVFEQNQGLPLRRHHSDLYSHYFGGLAETVLVVRSMSTLLNYDYVWDTVFH 480 Query: 481 PSGAIEIRFYATGYISSAFLFGATGKYGNQVSEHTLGTVHTHSAHFKVDLDVAGLENWVW 540 PSGAIEIRFYATGYISSAFLFGATGKYGNQVSEHTLGTVHTHSAHFKVDLDVAGLENWVW Sbjct: 481 PSGAIEIRFYATGYISSAFLFGATGKYGNQVSEHTLGTVHTHSAHFKVDLDVAGLENWVW 540 Query: 541 AEDMVFVPMAVPWSPEHQLQRLQVTRKLLEMEEQAAFLVGSATPRYLYLASNHSNKWGHP 600 AEDMVFVPMAVPWSPEHQLQRLQVTRKLLEMEEQAAFLVGSATPRYLYLASNHSNKWGHP Sbjct: 541 AEDMVFVPMAVPWSPEHQLQRLQVTRKLLEMEEQAAFLVGSATPRYLYLASNHSNKWGHP 600 Query: 601 RGYRIQMLSFAGEPLPQNSSMARGFSWERYQLAVTQRKEEEPSSSSVFNQNDPWAPTVDF 660 RGYRIQMLSFAGEPLPQNSSMARGFSWERYQLAVTQRKEEEPSSSSVFNQNDPWAPTVDF Sbjct: 601 RGYRIQMLSFAGEPLPQNSSMARGFSWERYQLAVTQRKEEEPSSSSVFNQNDPWAPTVDF 660 Query: 661 SDFINNETIAGKDLVAWVTAGFLHIPHAEDIPNTVTVGNGVGFFLRPYNFFDEDPSFYSA 720 SDFINNETIAGKDLVAWVTAGFLHIPHAEDIPNTVTVGNGVGFFLRPYNFFDEDPSFYSA Sbjct: 661 SDFINNETIAGKDLVAWVTAGFLHIPHAEDIPNTVTVGNGVGFFLRPYNFFDEDPSFYSA 720 Query: 721 DSIYFRGDQDAGACEVNPLACLPQAAACAPDLPAFSHGGFSHN 763 DSIYFRGDQDAGACEVNPLACLPQAAACAPDLPAFSHGGFSHN Sbjct: 721 DSIYFRGDQDAGACEVNPLACLPQAAACAPDLPAFSHGGFSHN 763 >2PNC-A nrPDB Length = 746 Score = 1274 bits (3298), Expect = 0.0, Method: Compositional matrix adjust. Identities = 602/726 (82%), Positives = 658/726 (90%) Query: 35 PSQLPHCPSVSPSAQPWTHPGQSQLFADLSREELTAVMRFLTQRLGPGLVDAAQARPSDN 94 PS P CPS SPS QPWTHP QSQLFADLSREELT VM FLTQ+LGP LVDAAQARPSDN Sbjct: 18 PSLPPRCPSRSPSDQPWTHPDQSQLFADLSREELTTVMSFLTQQLGPDLVDAAQARPSDN 77 Query: 95 CVFSVELQLPPKAAALAHLDRGSPPPAREALAIVFFGRQPQPNVSELVVGPLPHPSYMRD 154 CVFSVELQLPPKAAALAHLDRGSPPPAREALAIVFFG QPQPNV+ELVVGPLP PSYMRD Sbjct: 78 CVFSVELQLPPKAAALAHLDRGSPPPAREALAIVFFGGQPQPNVTELVVGPLPQPSYMRD 137 Query: 155 VTVERHGGPLPYHRRPVLFQEYLDIDQMIFNRELPQASGLLHHCCFYKHRGRNLVTMTTA 214 VTVERHGGPLPY+RRPVL +EYLDIDQMIFNRELPQA+G+LHHCC YK G+ L+TM +A Sbjct: 138 VTVERHGGPLPYYRRPVLLREYLDIDQMIFNRELPQAAGVLHHCCSYKQGGQKLLTMNSA 197 Query: 215 PRGLQSGDRATWFGLYYNISGAGFFLHHVGLELLVNHKALDPARWTIQKVFYQGRYYDSL 274 PRG+QSGDR+TWFG+YYNI+ G +LH VGLELLV+HKALDPA WT+QKVF+QGRYY++L Sbjct: 198 PRGVQSGDRSTWFGIYYNITKGGPYLHPVGLELLVDHKALDPADWTVQKVFFQGRYYENL 257 Query: 275 AQLEAQFEAGLVNVVLIPDNGTGGSWSLKSPVPPGPAPPLQFYPQGPRFSVQGSRVASSL 334 AQLE QFEAG VNVV+IPD+GTGG WSLKS VPPGP PPLQF+PQGPRFSVQG+RVASSL Sbjct: 258 AQLEEQFEAGQVNVVVIPDDGTGGFWSLKSQVPPGPTPPLQFHPQGPRFSVQGNRVASSL 317 Query: 335 WTFSFGLGAFSGPRIFDVRFQGERLVYEISLQEALAIYGGNSPAAMTTRYVDGGFGMGKY 394 WTFSFGLGAFSGPR+FDVRFQGERL YEISLQEA A+YGGN+PAAM TRY+D GFGMG + Sbjct: 318 WTFSFGLGAFSGPRVFDVRFQGERLAYEISLQEAGAVYGGNTPAAMLTRYMDSGFGMGYF 377 Query: 395 TTPLTRGVDCPYLATYVDWHFLLESQAPKTIRDAFCVFEQNQGLPLRRHHSDLYSHYFGG 454 TPL RGVDCPYLATY+DWHF++ESQ PKT+ DAFCVFEQN+GLPLRRHHSD SHYFGG Sbjct: 378 ATPLIRGVDCPYLATYMDWHFVVESQTPKTLHDAFCVFEQNKGLPLRRHHSDFLSHYFGG 437 Query: 455 LAETVLVVRSMSTLLNYDYVWDTVFHPSGAIEIRFYATGYISSAFLFGATGKYGNQVSEH 514 +A+TVLV RS+ST+LNYDYVWD VF+P+GAIE++ +ATGYISSAFLFGA +YGNQV EH Sbjct: 438 VAQTVLVFRSVSTMLNYDYVWDMVFYPNGAIEVKLHATGYISSAFLFGAARRYGNQVGEH 497 Query: 515 TLGTVHTHSAHFKVDLDVAGLENWVWAEDMVFVPMAVPWSPEHQLQRLQVTRKLLEMEEQ 574 TLG VHTHSAH+KVDLDV GLENWVWAEDM FVP A+PWSPEHQ+QRLQVTRK LE EEQ Sbjct: 498 TLGPVHTHSAHYKVDLDVGGLENWVWAEDMAFVPTAIPWSPEHQIQRLQVTRKQLETEEQ 557 Query: 575 AAFLVGSATPRYLYLASNHSNKWGHPRGYRIQMLSFAGEPLPQNSSMARGFSWERYQLAV 634 AAF +G A+PRYLYLAS SNKWGHPRGYRIQ +SFAG P+PQNS M R FSW RYQLA+ Sbjct: 558 AAFPLGGASPRYLYLASKQSNKWGHPRGYRIQTVSFAGGPMPQNSPMERAFSWGRYQLAI 617 Query: 635 TQRKEEEPSSSSVFNQNDPWAPTVDFSDFINNETIAGKDLVAWVTAGFLHIPHAEDIPNT 694 TQRKE EPSSSSVFNQNDPW PTVDFSDFINNETIAGKDLVAWVTAGFLHIPHAEDIPNT Sbjct: 618 TQRKETEPSSSSVFNQNDPWTPTVDFSDFINNETIAGKDLVAWVTAGFLHIPHAEDIPNT 677 Query: 695 VTVGNGVGFFLRPYNFFDEDPSFYSADSIYFRGDQDAGACEVNPLACLPQAAACAPDLPA 754 VTVGNGVGFFLRPYNFFD++PS SADSIYFR QDAG+CE+NPLACLPQAA CAPDLP Sbjct: 678 VTVGNGVGFFLRPYNFFDQEPSMDSADSIYFREGQDAGSCEINPLACLPQAATCAPDLPV 737 Query: 755 FSHGGF 760 FSHGG+ Sbjct: 738 FSHGGY 743 >3K5T-A nrPDB Length = 731 Score = 522 bits (1345), Expect = e-148, Method: Compositional matrix adjust. Identities = 293/736 (39%), Positives = 417/736 (56%), Gaps = 38/736 (5%) Query: 50 PWTHPGQSQLFADLSREELTAVMRFLTQRLGPGLVDAAQARPSDNCVFSVELQLPPKAAA 109 P T P ++ +F+DLS +EL AV FL + L ++ + N VF +E+ LP K Sbjct: 3 PGTLPRKAGVFSDLSNQELKAVHSFLWSKKELRLQPSSTTTMAKNTVFLIEMLLPKKYHV 62 Query: 110 LAHLDRGSPPPAREALAIVFFGRQPQPNVSELVVGPLPHPSYMRDVTVERHGGPLPYHRR 169 L LD+G P REA A++FFG Q PNV+E VGPLP P YMR ++ R G + R Sbjct: 63 LRFLDKGERHPVREARAVIFFGDQEHPNVTEFAVGPLPGPCYMRALS-PRPGYQSSWASR 121 Query: 170 PVLFQEYLDIDQMIFNRELPQASGLLHHC-------CFYKHRGRNLVTMTTAPRGLQSGD 222 P+ EY + L +A+ LH F R L APRG+ SG Sbjct: 122 PISTAEY-----ALLYHTLQEATKPLHQFFLNTTGFSFQDCHDRCLAFTDVAPRGVASGQ 176 Query: 223 RATWFGLYYNISGAGFFLHHVGLELLVNHKALDPARWTIQKVFYQGRYYDSLAQLEAQFE 282 R +W + + G +FLH GLELLV+H + D W +++V+Y G++Y S +L ++ Sbjct: 177 RRSWLIIQRYVEG--YFLHPTGLELLVDHGSTDAGHWAVEQVWYNGKFYGSPEELARKYA 234 Query: 283 AGLVNVVLIPDNGTGGSWSLKSPVPP----------GPAP-----PLQFYPQGPRFSVQG 327 G V+VV++ D GG + PP P+P P P GPRF ++G Sbjct: 235 DGEVDVVVLEDPLPGGKGHDSTEEPPLFSSHKPRGDFPSPIHVSGPRLVQPHGPRFRLEG 294 Query: 328 SRVASSLWTFSFGLGAFSGPRIFDVRFQGERLVYEISLQEALAIYGGNSPAAMTTRYVDG 387 + V W+F+F L + SG ++ +V F GER+ YE+S+QEA+A+YGG++PA M T+Y+D Sbjct: 295 NAVLYGGWSFAFRLRSSSGLQVLNVHFGGERIAYEVSVQEAVALYGGHTPAGMQTKYLDV 354 Query: 388 GFGMGKYTTPLTRGVDCPYLATYVDWHFLLESQAPKTIRDAFCVFEQNQGLPLRRHHSDL 447 G+G+G T L G+DCP AT++D ++ P A C+FE G+PLRRH + Sbjct: 355 GWGLGSVTHELAPGIDCPETATFLDTFHYYDADDPVHYPRALCLFEMPTGVPLRRHFNSN 414 Query: 448 YS---HYFGGLAETVLVVRSMSTLLNYDYVWDTVFHPSGAIEIRFYATGYISSAFLFGAT 504 + +++ GL VLV+R+ ST+ NYDY+WD +F+P+G +E + +ATGY+ + F Sbjct: 415 FKGGFNFYAGLKGQVLVLRTTSTVYNYDYIWDFIFYPNGVMEAKMHATGYVHATFYTPEG 474 Query: 505 GKYGNQVSEHTLGTVHTHSAHFKVDLDVAGLENWVWAEDMVFVPMAVPWSPEHQLQRLQV 564 ++G ++ H +G +HTH H++VDLDVAG +N M + PWSP H++ + + Sbjct: 475 LRHGTRLHTHLIGNIHTHLVHYRVDLDVAGTKNSFQTLQMKLENITNPWSPRHRVVQPTL 534 Query: 565 TRKLLEMEEQAAFLVGSATPRYLYLASNHSNKWGHPRGYRIQMLSFAGEPLPQNSSMARG 624 + E QAAF P+YL S N WGH R YR+Q+ S A + LP + Sbjct: 535 EQTQYSWERQAAFRFKRKLPKYLLFTSPQENPWGHKRSYRLQIHSMADQVLPPGWQEEQA 594 Query: 625 FSWERYQLAVTQRKEEEPSSSSVFNQNDPWAPTVDFSDFI-NNETIAGKDLVAWVTAGFL 683 +W RY LAVT+ +E E SSS+++QNDPW P V F F+ NNE I +DLVAWVT GFL Sbjct: 595 ITWARYPLAVTKYRESELCSSSIYHQNDPWDPPVVFEQFLHNNENIENEDLVAWVTVGFL 654 Query: 684 HIPHAEDIPNTVTVGNGVGFFLRPYNFFDEDPSFYSADSIYFRGDQDAGACEVNPLACLP 743 HIPH+EDIPNT T GN VGF LRP+NFF EDPS S D++ +D G V +P Sbjct: 655 HIPHSEDIPNTATPGNSVGFLLRPFNFFPEDPSLASRDTVIV-WPRDNGPNYVQ--RWIP 711 Query: 744 QAAACAPDLPAFSHGG 759 + C+ P FS+ G Sbjct: 712 EDRDCSMP-PPFSYNG 726 >3PGB-A nrPDB Length = 797 Score = 276 bits (706), Expect = 2e-74, Method: Compositional matrix adjust. Identities = 204/703 (29%), Positives = 329/703 (46%), Gaps = 44/703 (6%) Query: 56 QSQLFADLSREELTAVMRFLTQRLGPGLVDAAQARPSDNCVFSVELQLPPKAAALAHLDR 115 + ++ L+ +E V ++L R L A DN + +EL P K+ A+ +LD Sbjct: 64 KENVWYGLTDDETADVAKWLFGRPELNLTTTENAGEWDNTIALIELHRPNKSEAIPYLDG 123 Query: 116 GSPPPAREALAIVFFGRQPQPNVSELVVGPLPHPSYMRDVTVERHGGPL--PYHRRPVLF 173 P P R A + P ++++VGPLP V+ PL PY R+ Sbjct: 124 SGPAPTRHAHVRLNNRATTDPYFADILVGPLP-------VSNATTWEPLEFPYTRKTQGQ 176 Query: 174 QEYLDID-QMIFNRELPQASGLLHHCCFYKHRGR--NLVTMTTAPRGL----QSGDRATW 226 ++ D + +++ L + S + G L T G+ Q R Sbjct: 177 VRNVEPDGETVYSEWLFKISASIADITLDLWNGTALGLENDTLDIWGIDPLWQDDGRIIR 236 Query: 227 FGLYYNISGAGF---FLHHVGLELLVNHKALDPARWTIQKVFYQGRYYDSLAQL-EAQFE 282 + +++N++ F L +GL L + DP++W + Y +Y++ + +A + Sbjct: 237 WDMFWNMADDEFDSETLLPLGLYLKSDVTGRDPSQWKLLGWMYNDIFYETTEEFRKAYWS 296 Query: 283 AGLVNVVLIPDNGTGGSWS---LKSPVPPG--PAPPLQFYPQGPRFSVQGSRVASSLWTF 337 G V L P+ G+W+ + PVPP PP+ P G R+SV R + F Sbjct: 297 PGFVK--LKPN--VDGAWAHTEQRGPVPPQDRKQPPVMIAPDGARYSVDAERKYVTWMDF 352 Query: 338 SF--GLGAFSGPRIFDVRFQGERLVYEISLQEALAIYGGNSPAAMTTRYVDGGFGMGKYT 395 SF +G +FD++++G+R++YE+ LQEALA Y N P + Y+D +G G Y Sbjct: 353 SFYIAFNRDTGLSLFDIKYKGQRVLYELGLQEALAHYAANDPVQSSVAYLDSYYGFGPYA 412 Query: 396 TPLTRGVDCPYLATYVDWHFLLESQAPKTIRDAFCVFEQNQGLPLRRHHSDLYSHYFGGL 455 L +G DCP A+Y++ F + + T D+ C+FE + P+ RH + S + Sbjct: 413 FELLKGYDCPSYASYLNTSFYKDEET-HTHVDSLCLFEFDADYPMARHST---SEFVSVT 468 Query: 456 AETVLVVRSMSTLLNYDYVWDTVFHPSGAIEIRFYATGYISSAFLFGATGKYGNQVSEHT 515 +RS+ST+ NYDY++ FH G I + A+GYI SA+ + +G Q+ + Sbjct: 469 KNVYFTLRSVSTIGNYDYMFSYNFHMDGTIGVEVRASGYIQSAY-YANNQDFGYQIHDSL 527 Query: 516 LGTVHTHSAHFKVDLDVAGLENWVWAEDMVFVPMAVPWSPEHQLQRLQVTRKLLEMEEQA 575 G++H H +FK D D+ G N + +V V WS +Q+ R + E++A Sbjct: 528 SGSMHDHVLNFKADFDILGPNNTIELVSVVPVTKQFSWSGNKTRNTMQLGRSFIHSEDEA 587 Query: 576 AFLVGSATPRYLYLAS-NHSNKWGHPRGYRIQMLSFAGEP---LPQNSSMARGFSWERYQ 631 G L++ + + NK+G PRGYRI L AG + +S++ W Y Sbjct: 588 RLNWGFNGQTQLHVVNQDKPNKFGEPRGYRI--LPSAGTAHLTVLNSSNLVHAAHWAEYD 645 Query: 632 LAVTQRKEEEPSSSSVFNQNDPWAPTVDFSDFINNETIAGKDLVAWVTAGFLHIPHAEDI 691 + VT++ + EP+S+ +N D P VDFS F N E++ DLV W+ G H+PH D+ Sbjct: 646 VQVTRQHDFEPTSAHPYNSQDIHNPPVDFSTFFNGESLNQTDLVVWLNLGMHHVPHTGDL 705 Query: 692 PNTVTVGNGVGFFLRPYNFFDEDPSFYSADSIYFRGDQDAGAC 734 PNTV G P N+ DPS + + + R D GA Sbjct: 706 PNTVFTTAHSGVAFTPLNYLPGDPSRETVNMV--RVDYSDGAA 746 >1RKY-A nrPDB Length = 747 Score = 218 bits (554), Expect = 1e-56, Method: Compositional matrix adjust. Identities = 194/719 (26%), Positives = 309/719 (42%), Gaps = 77/719 (10%) Query: 56 QSQLFADLSREELTAVMRFLTQRLGPGLVDAAQARPSDNCVFSVELQLPPKAAALAHLDR 115 ++ ++ L++EE+ V+ L + + +A N V +E P K AL +LD Sbjct: 17 KTNIWTSLAKEEVQEVLDLLHSTYN--ITEVTKADFFSNYVLWIETLKPNKTEALTYLDE 74 Query: 116 GSPPPAREALAIVFFGRQPQPNVSELVVGPLPHPSYMRDVTVERHGGPLPYHRRPVLFQE 175 P R A +V+FG + EL VGPLP V+ E PL ++ + Sbjct: 75 DGDLPPRNARTVVYFGEGEEGYFEELKVGPLP-------VSDETTIEPLSFYNTNGKSKL 127 Query: 176 YLDIDQMIFNRELPQASGLLHHCCFYKHRGRNLVTMTTAPRGL---------------QS 220 ++ + + ++S L ++ N M GL Q Sbjct: 128 PFEVGHLDRIKSAAKSSFL--------NKNLNTTIMRDVLEGLIGVPYEDMGCHSAAPQL 179 Query: 221 GDRATWFGLYY-----NISGAGFFLHHVGLELLVNHKALDPARWTIQKVFYQGRYYDSLA 275 D AT + Y N L G + D ++W + + Y + Y S Sbjct: 180 HDPATGATVDYGTCNINTENDAENLVPTGFFFKFDMTGRDVSQWKMLEYIYNNKVYTSAE 239 Query: 276 QL-EAQFEAGLVNVVLIPDNGTGGSWSLKSPVPPGPA-------PPLQFYPQGPRFSVQG 327 +L EA + V + I + W++ P P P+G R++ G Sbjct: 240 ELYEAMQKDDFVTLPKIDVDNL--DWTVIQRNDSAPVRHLDDRKSPRLVEPEGRRWAYDG 297 Query: 328 SRVASSL--WTFSFGLGAFSGPRIFDVRFQGERLVYEISLQEALAIYGGNSPAAMTTRYV 385 S W F +G +D+ F+GER+VYE+SLQE +A YG + P T Y Sbjct: 298 DEEYFSWMDWGFYTSWSRDTGISFYDITFKGERIVYELSLQELIAEYGSDDPFNQHTFYS 357 Query: 386 DGGFGMGKYTTPLTRGVDCPYLATYVDWH-FLLESQAPKTIRDAFCVFEQNQGLPLRRHH 444 D +G+G + L G DCP A Y F + +T+ ++CVFE + L RH Sbjct: 358 DISYGVGNRFS-LVPGYDCPSTAGYFTTDTFEYDEFYNRTL--SYCVFENQEDYSLLRHT 414 Query: 445 SDLYSHYFGGLAETVLVVRSMSTLLNYDYVWDTVFHPSGAIEIRFYATGYISSAFLFGAT 504 YS L VR +ST+ NYDY + F G +E+ A GYI + + T Sbjct: 415 GASYS---AITQNPTLNVRFISTIGNYDYNFLYKFFLDGTLEVSVRAAGYIQAGYWNPET 471 Query: 505 GK-YGNQVSEHTLGTVHTHSAHFKVDLDVAGLENWVWAEDMVFVPMAVPWSPEHQLQRLQ 563 YG ++ + G+ H H ++KVDLDV G +N M V + PW+P Q Sbjct: 472 SAPYGLKIHDVLSGSFHDHVLNYKVDLDVGGTKNRASQYVMKDVDVEYPWAPGTVYNTKQ 531 Query: 564 VTRKLLEMEE----------QAAFLVGSATPRYLYLASNHSNKWGHPRGYRIQMLSFAGE 613 + R++ E E+ Q L+ SA +N +G+PR Y I Sbjct: 532 IAREVFENEDFNGINWPENGQGILLIESA---------EETNSFGNPRAYNIMPGGGGVH 582 Query: 614 PLPQNS-SMARGFSWERYQLAVTQRKEEEPSSSSVFNQNDPWAPTVDFSDFINNETIAGK 672 + +NS S +W R L +T+ K+ E SS+ N N + P V+F+ F+++E++ G+ Sbjct: 583 RIVKNSRSGPETQNWARSNLFLTKHKDTELRSSTALNTNALYDPPVNFNAFLDDESLDGE 642 Query: 673 DLVAWVTAGFLHIPHAEDIPNTVTVGNGVGFFLRPYNFFDEDPSFYSADSIYFRGDQDA 731 D+VAWV G H+P++ D+PNT+ F L P+N+FD + S + +++ D + Sbjct: 643 DIVAWVNLGLHHLPNSNDLPNTIFSTAHASFMLTPFNYFDSENSRDTTQQVFYTYDDET 701 >1D6Z-A nrPDB Length = 727 Score = 136 bits (343), Expect = 3e-32, Method: Compositional matrix adjust. Identities = 123/436 (28%), Positives = 191/436 (43%), Gaps = 32/436 (7%) Query: 303 KSPVPPGPAPPLQFYPQGPRFSVQGSRVASSLWTFSFGLGAFSGPRIFDVRFQGE----R 358 + V P P P+G +++ G + W F + + GP I V + + Sbjct: 296 RDRVAPAVKPMQIIEPEGKNYTITGDMIHWRNWDFHLSMNSRVGPMISTVTYNDNGTKRK 355 Query: 359 LVYEISLQEALAIYGGNSPAAMTTRYVDGG-FGMGKYTTPLTRGVDCPYLATYVDWHFLL 417 ++YE SL + YG Y+D G +GMG T+P+ RG D P A ++ Sbjct: 356 VMYEGSLGGMIVPYGDPDIGWYFKAYLDSGDYGMGTLTSPIARGKDAPSNAVLLNETIAD 415 Query: 418 ESQAPKTIRDAFCVFEQNQGLPLRRHHSDLYSHYFGGLAETVLVVRSMSTLLNYDYVWDT 477 + P I A VFE+ G P +H + E LVVR +ST+ NYDY++D Sbjct: 416 YTGVPMEIPRAIAVFERYAG-PEYKHQEMGQPNVSTERRE--LVVRWISTVGNYDYIFDW 472 Query: 478 VFHPSGAIEIRFYATGY-----ISSAFLFGATGK----YGNQVSEHTLGTVHTHSAHFKV 528 +FH +G I I ATG + + + T K YG + + +GT H H +F++ Sbjct: 473 IFHENGTIGIDAGATGIEAVKGVKAKTMHDETAKDDTRYGTLIDHNIVGTTHQHIYNFRL 532 Query: 529 DLDVAGLENWVWAEDMVFVPMAVPWSPEHQLQRLQVTRKLLEMEEQAAFLVGSATPRYLY 588 DLDV G N + A D V P + + +QV + + E+ AA T R L Sbjct: 533 DLDVDGENNSLVAMDPVVKPNT---AGGPRTSTMQVNQYNIGNEQDAAQKFDPGTIRLLS 589 Query: 589 LASNHSNKWGHPRGYRIQMLSFAGEPLPQNSSMA------RGFSWERYQLAVTQRKEEEP 642 N N+ G+P Y+I + P+ + + A S+ QL VT+ E Sbjct: 590 -NPNKENRMGNPVSYQIIPYAGGTHPVAKGAQFAPDEWIYHRLSFMDKQLWVTRYHPGER 648 Query: 643 SSSSVF-NQNDPWAPTVDFSDFINNETIAGKDLVAWVTAGFLHIPHAEDIPNTVTVGNGV 701 + N++ +S +NE++ D V W+T G H+ AE+ P + V Sbjct: 649 FPEGKYPNRSTHDTGLGQYSK--DNESLDNTDAVVWMTTGTTHVARAEEWP--IMPTEWV 704 Query: 702 GFFLRPYNFFDEDPSF 717 L+P+NFFDE P+ Sbjct: 705 HTLLKPWNFFDETPTL 720 >2CG0-A nrPDB Length = 646 Score = 123 bits (309), Expect = 3e-28, Method: Compositional matrix adjust. Identities = 117/423 (27%), Positives = 185/423 (43%), Gaps = 19/423 (4%) Query: 302 LKSPVPPGPAPPLQFYPQGPRFSVQG-SRVASSLWTFSFGLGAFSGPRIFDVRFQ-GERL 359 L P+ P P+GP F+V G + + W+ G G + ++ F+ G+RL Sbjct: 207 LTGPLRTTQKPISITQPEGPSFTVTGGNHIEWEKWSLDVGFDVREGVVLHNIAFRDGDRL 266 Query: 360 ---VYEISLQEALAIYGGNSPAAMTTRYVDGG-FGMGKYTTPLTRGVDCPYLATYVDWHF 415 + S+ E + YG SP Y D G + +G+Y L G DC TY+ Sbjct: 267 RPIINRASIAEMVVPYGDPSPIRSWQNYFDTGEYLVGQYANSLELGCDCLGDITYLSPVI 326 Query: 416 LLESQAPKTIRDAFCVFEQNQGLPLRRHHSDLYSHYFGGLAETVLVVRSMSTLLNYDYVW 475 P+ IR+ C+ E++ G+ + HSDL+S +V+ +T+ NYDY + Sbjct: 327 SDAFGNPREIRNGICMHEEDWGILAK--HSDLWSGINYTRRNRRMVISFFTTIGNYDYGF 384 Query: 476 DTVFHPSGAIEIRFYATGYI-SSAFLFGATGKYGNQVSEHTLGTVHTHSAHFKVDLDVAG 534 + G IE ATG + +SAF G + +Q++ H H ++D+ + G Sbjct: 385 YWYLYLDGTIEFEAKATGVVFTSAFPEGGSDNI-SQLAPGLGAPFHQHIFSARLDMAIDG 443 Query: 535 LENWVWAEDMVFVPMAVPWSPEHQLQRLQVTRKLLEMEEQAAFLVGSATPRYLYLASNHS 594 N V ED+V M + R R +L E +A + T R +++ S Sbjct: 444 FTNRVEEEDVVRQTMGPGNERGNAFSR---KRTVLTRESEAVREADARTGRTWIISNPES 500 Query: 595 -NKWGHPRGYRIQMLSFAGEPLPQNSSMARGFSWERYQLAVTQRKEEEPSSSSVF-NQND 652 N+ P GY++ + SS+AR ++ L VT+ ++E + F NQ+ Sbjct: 501 KNRLNEPVGYKLHAHNQPTLLADPGSSIARRAAFATKDLWVTRYADDERYPTGDFVNQHS 560 Query: 653 PWAPTVDFSDFINNETIAGKDLVAWVTAGFLHIPHAEDIPNTVTVGNGVGFFLRPYNFFD 712 A + + I G+D+V W T G H P ED P + + VGF LRP FFD Sbjct: 561 GGAGLPSY--IAQDRDIDGQDIVVWHTFGLTHFPRVEDWP--IMPVDTVGFKLRPEGFFD 616 Query: 713 EDP 715 P Sbjct: 617 RSP 619 >3LOY-A nrPDB Length = 633 Score = 123 bits (309), Expect = 3e-28, Method: Compositional matrix adjust. Identities = 107/413 (25%), Positives = 179/413 (43%), Gaps = 31/413 (7%) Query: 318 PQGPRFSVQGSRVASSLWTFSFGLGAFSGPRIFDVRFQGERLVYEISLQEALAIYGG-NS 376 P+GP F+V G +++ W F G I+D+ F+G +VY +SL E YG + Sbjct: 233 PEGPSFNVDGHKISWQGWEFFVIPTVREGFAIYDIHFKGRSVVYRLSLSEMTVPYGDPRA 292 Query: 377 PAAMTTRYVDGGFGMGKYTTPLTRGVDCPYLATYVDWHFLLESQAPKTIRDAFCVFEQNQ 436 P + G G G L G DC + Y+D + + I + C+ EQ+ Sbjct: 293 PFHRKQAFDLGDCGFGATGNSLALGCDCLGVIKYMDCRRVNTNGDSVLIPNTVCLHEQDG 352 Query: 437 GLPLRRHHSDLYSHYFGGLAETVLVVRSMSTLLNYDYVWDTVFHPSGAIEIRFYATGYIS 496 GL + H++ ++ VV++++T+ NY+Y+ + +F +G I I ATG +S Sbjct: 353 GLLYK--HTNYRTNVPVIARRREFVVQTIATVANYEYMLNIIFDQAGEIRIHVRATGILS 410 Query: 497 SAFL-FGATGKYGNQVSEHTLGTVHTHSAHFKVDLDVAGLENWVWAEDMVFVPMAVPWSP 555 + L T +G V + H H F++D V G EN V +D++ + +P Sbjct: 411 TMPLDKDVTVPWGTNVGPRVMAAYHQHMLSFRIDPAVDGYENTVVFDDVIRMEKNTKLNP 470 Query: 556 EHQLQRLQVTRKLLEME---EQAAFLVGSATPRYLYLASNHSNKWG-HPRGYRIQMLSFA 611 + R ++E EQ+ F S Y + N N P Y+I M + Sbjct: 471 YN--VGFVTERTVVEKPGYVEQSPFTNRS----YKIINENKINPISKKPVAYKIMMPARQ 524 Query: 612 GEPLPQNSSMARGFSWERYQLAVTQRKEEEPSSSSVF---NQNDP----WAPTVDFSDFI 664 ++S + + Q+ VT+ ++ E ++ F +Q D WA Sbjct: 525 MLLADEDSYNNKRAQFATQQVWVTKYRDNELYAAGEFTNQSQTDTGLGVWAR-------- 576 Query: 665 NNETIAGKDLVAWVTAGFLHIPHAEDIPNTVTVGNGVGFFLRPYNFFDEDPSF 717 +E + + V W T GF HIP ED P + + L P+ FFD++P+ Sbjct: 577 RDENVRNDNPVVWATLGFTHIPRVEDFPVMPVEAHEIA--LVPFGFFDKNPAL 627 >1KSI-A nrPDB Length = 642 Score = 110 bits (274), Expect = 3e-24, Method: Compositional matrix adjust. Identities = 102/417 (24%), Positives = 172/417 (41%), Gaps = 29/417 (6%) Query: 318 PQGPRFSVQGSRVASSLWTFSFGLGAFSG-----PRIFDV-RFQGERLVYEISLQEALAI 371 PQGP F + G V+ + W F G +G I+D+ + + R++Y+ + E Sbjct: 221 PQGPGFQINGHSVSWANWKFHIGFDVRAGIVISLASIYDLEKHKSRRVLYKGYISELFVP 280 Query: 372 YGGNSPAAMTTRYVDGG-FGMGKYTTPLTRGVDCPYLATYVDWHFLLESQAPKTIRDAFC 430 Y + + D G FG G T L DCP A ++D + + P +++A C Sbjct: 281 YQDPTEEFYFKTFFDSGEFGFGLSTVSLIPNRDCPPHAQFIDTYVHSANGTPILLKNAIC 340 Query: 431 VFEQNQGLPLRRHHSDLYSHYF-GGLAETVLVVRSMSTLLNYDYVWDTVFHPSGAIEIRF 489 VFEQ + R + + + E L+VR++ T+ NYD V D F SG+I+ Sbjct: 341 VFEQYGNIMWRHTENGIPNESIEESRTEVNLIVRTIVTVGNYDNVIDWEFKASGSIKPSI 400 Query: 490 YATGYISSAFLFGATGKYGNQVSE---------HTLGTVHTHSAHFKVDLDVAGLENWVW 540 +G + + G K+ +++ E +++G H H + +D D+ G N Sbjct: 401 ALSGILE---IKGTNIKHKDEIKEDLHGKLVSANSIGIYHDHFYIYYLDFDIDGTHNSF- 456 Query: 541 AEDMVFVPMAVPWSPEHQLQRLQVTRKLLEMEEQAAFLVGSATPRYLYLASNHSNKWGHP 600 E + + + + + E A +G A + + N G+ Sbjct: 457 -EKTSLKTVRIKDGSSKRKSYWTTETQTAKTESDAKITIGLAPAELVVVNPNIKTAVGNE 515 Query: 601 RGYRIQMLSFAGEPL--PQNSSMARGFSWERYQLAVTQRKEEEPSSSSVFNQNDPWAPTV 658 GYR+ + + PL + RG ++ Y + VT E + ++ + T+ Sbjct: 516 VGYRL-IPAIPAHPLLTEDDYPQIRG-AFTNYNVWVTAYNRTEKWAGGLYVDHSRGDDTL 573 Query: 659 DFSDFINNETIAGKDLVAWVTAGFLHIPHAEDIPNTVTVGNGVGFFLRPYNFFDEDP 715 N E I KD+V W G H+P ED P + F LRP NFF+ +P Sbjct: 574 AVWTKQNRE-IVNKDIVMWHVVGIHHVPAQEDFPIMPLL--STSFELRPTNFFERNP 627 >3NBJ-A nrPDB Length = 692 Score = 99.8 bits (247), Expect = 4e-21, Method: Compositional matrix adjust. Identities = 111/424 (26%), Positives = 176/424 (41%), Gaps = 24/424 (5%) Query: 311 APPLQF-YPQGPRFSVQGSRVASSLWTFSFGLGAFSGPRIFDVRFQGERLV----YEISL 365 APP+ P+G F + G+ + S + F G G + DV + V + ISL Sbjct: 239 APPINVTQPEGVSFKMTGNVMEWSNFKFHIGFNYREGIVLSDVSYNDHGNVRPIFHRISL 298 Query: 366 QEALAIYGGNSPAAMTTRYVD-GGFGMGKYTTPLTRGVDCPYLATYVDWHFLLESQAPKT 424 E + +G +D G +G G T PL+ G DC + Y+D HF + P T Sbjct: 299 SEMIVPFGSPEFPHQRKHALDIGEYGAGYMTNPLSLGCDCKGVIHYLDAHFSDRAGDPIT 358 Query: 425 IRDAFCVFEQNQGLPLRRHHSDLYSHYFGGLAE--TVLVVRSMSTLLNYDYVWDTVFHPS 482 +++A C+ E++ GL + HSD ++ L T LVV + T N +Y VF Sbjct: 359 VKNAVCIHEEDDGLLFK--HSDFRDNFATSLVTRATKLVVSQIFTAANXEYCLYWVFMQD 416 Query: 483 GAIEIRFYATGYISSAFLFG--ATGKYGNQVSEHTLGTVHTHSAHFKVDLDVAGLENWVW 540 GAI + TG +++ L G +G +V + H H ++D + G N Sbjct: 417 GAIRLDIRLTGILNTYILGDDEEAGPWGTRVYPNVNAHNHQHLFSLRIDPRIDGDGNSAA 476 Query: 541 AEDMVFVPMAVPWSPEHQLQRLQVTRK-LLEMEEQAAFLVGSATPR-YLYLASNHSNKW- 597 A D P + SPE+ + K + + + SAT R + N N + Sbjct: 477 ACDAKSSPYPL-GSPENMYGNAFYSEKTTFKTVKDSLTNYESATGRSWDIFNPNKVNPYS 535 Query: 598 GHPRGYRIQMLSFAGEPL--PQNSSMARGFSWERYQLAVTQRKEEE--PSSSSVFNQNDP 653 G P Y+ ++S PL + S +A+ W + + V K+ PS V + Sbjct: 536 GKPPSYK--LVSTQCPPLLAKEGSLVAKRAPWASHSVNVVPYKDNRLYPSGDHVPQWSGD 593 Query: 654 WAPTVDFSDFINNETIAGKDLVAWVTAGFLHIPHAEDIPNTVTVGNGVGFFLRPYNFFDE 713 + +E I D++ + T G H P ED P + + LRP +FF E Sbjct: 594 GVRGMREWIGDGSENIDNTDILFFHTFGITHFPAPEDFP--LXPAEPITLMLRPRHFFTE 651 Query: 714 DPSF 717 +P Sbjct: 652 NPGL 655 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 1US1-A nrPDB 1165 0.0 2PNC-A nrPDB 1063 0.0 3K5T-A nrPDB 889 0.0 3PGB-A nrPDB 773 0.0 1RKY-A nrPDB 718 0.0 1D6Z-A nrPDB 488 e-138 2CG0-A nrPDB 479 e-135 3NBJ-A nrPDB 472 e-133 3LOY-A nrPDB 465 e-131 1KSI-A nrPDB 449 e-126 Sequences not found previously or not previously below threshold: 2GVU-A nrPDB 34 0.26 4C9T-A nrPDB 33 0.56 4Q2R-A nrPDB 32 0.68 3PKO-A nrPDB 31 2.3 3IHG-A nrPDB 30 3.7 CONVERGED! >1US1-A nrPDB Length = 763 Score = 1165 bits (3013), Expect = 0.0, Method: Composition-based stats. Identities = 763/763 (100%), Positives = 763/763 (100%) Query: 1 MNQKTILVLLILAVITIFALVCVLLVGRGGDGGEPSQLPHCPSVSPSAQPWTHPGQSQLF 60 MNQKTILVLLILAVITIFALVCVLLVGRGGDGGEPSQLPHCPSVSPSAQPWTHPGQSQLF Sbjct: 1 MNQKTILVLLILAVITIFALVCVLLVGRGGDGGEPSQLPHCPSVSPSAQPWTHPGQSQLF 60 Query: 61 ADLSREELTAVMRFLTQRLGPGLVDAAQARPSDNCVFSVELQLPPKAAALAHLDRGSPPP 120 ADLSREELTAVMRFLTQRLGPGLVDAAQARPSDNCVFSVELQLPPKAAALAHLDRGSPPP Sbjct: 61 ADLSREELTAVMRFLTQRLGPGLVDAAQARPSDNCVFSVELQLPPKAAALAHLDRGSPPP 120 Query: 121 AREALAIVFFGRQPQPNVSELVVGPLPHPSYMRDVTVERHGGPLPYHRRPVLFQEYLDID 180 AREALAIVFFGRQPQPNVSELVVGPLPHPSYMRDVTVERHGGPLPYHRRPVLFQEYLDID Sbjct: 121 AREALAIVFFGRQPQPNVSELVVGPLPHPSYMRDVTVERHGGPLPYHRRPVLFQEYLDID 180 Query: 181 QMIFNRELPQASGLLHHCCFYKHRGRNLVTMTTAPRGLQSGDRATWFGLYYNISGAGFFL 240 QMIFNRELPQASGLLHHCCFYKHRGRNLVTMTTAPRGLQSGDRATWFGLYYNISGAGFFL Sbjct: 181 QMIFNRELPQASGLLHHCCFYKHRGRNLVTMTTAPRGLQSGDRATWFGLYYNISGAGFFL 240 Query: 241 HHVGLELLVNHKALDPARWTIQKVFYQGRYYDSLAQLEAQFEAGLVNVVLIPDNGTGGSW 300 HHVGLELLVNHKALDPARWTIQKVFYQGRYYDSLAQLEAQFEAGLVNVVLIPDNGTGGSW Sbjct: 241 HHVGLELLVNHKALDPARWTIQKVFYQGRYYDSLAQLEAQFEAGLVNVVLIPDNGTGGSW 300 Query: 301 SLKSPVPPGPAPPLQFYPQGPRFSVQGSRVASSLWTFSFGLGAFSGPRIFDVRFQGERLV 360 SLKSPVPPGPAPPLQFYPQGPRFSVQGSRVASSLWTFSFGLGAFSGPRIFDVRFQGERLV Sbjct: 301 SLKSPVPPGPAPPLQFYPQGPRFSVQGSRVASSLWTFSFGLGAFSGPRIFDVRFQGERLV 360 Query: 361 YEISLQEALAIYGGNSPAAMTTRYVDGGFGMGKYTTPLTRGVDCPYLATYVDWHFLLESQ 420 YEISLQEALAIYGGNSPAAMTTRYVDGGFGMGKYTTPLTRGVDCPYLATYVDWHFLLESQ Sbjct: 361 YEISLQEALAIYGGNSPAAMTTRYVDGGFGMGKYTTPLTRGVDCPYLATYVDWHFLLESQ 420 Query: 421 APKTIRDAFCVFEQNQGLPLRRHHSDLYSHYFGGLAETVLVVRSMSTLLNYDYVWDTVFH 480 APKTIRDAFCVFEQNQGLPLRRHHSDLYSHYFGGLAETVLVVRSMSTLLNYDYVWDTVFH Sbjct: 421 APKTIRDAFCVFEQNQGLPLRRHHSDLYSHYFGGLAETVLVVRSMSTLLNYDYVWDTVFH 480 Query: 481 PSGAIEIRFYATGYISSAFLFGATGKYGNQVSEHTLGTVHTHSAHFKVDLDVAGLENWVW 540 PSGAIEIRFYATGYISSAFLFGATGKYGNQVSEHTLGTVHTHSAHFKVDLDVAGLENWVW Sbjct: 481 PSGAIEIRFYATGYISSAFLFGATGKYGNQVSEHTLGTVHTHSAHFKVDLDVAGLENWVW 540 Query: 541 AEDMVFVPMAVPWSPEHQLQRLQVTRKLLEMEEQAAFLVGSATPRYLYLASNHSNKWGHP 600 AEDMVFVPMAVPWSPEHQLQRLQVTRKLLEMEEQAAFLVGSATPRYLYLASNHSNKWGHP Sbjct: 541 AEDMVFVPMAVPWSPEHQLQRLQVTRKLLEMEEQAAFLVGSATPRYLYLASNHSNKWGHP 600 Query: 601 RGYRIQMLSFAGEPLPQNSSMARGFSWERYQLAVTQRKEEEPSSSSVFNQNDPWAPTVDF 660 RGYRIQMLSFAGEPLPQNSSMARGFSWERYQLAVTQRKEEEPSSSSVFNQNDPWAPTVDF Sbjct: 601 RGYRIQMLSFAGEPLPQNSSMARGFSWERYQLAVTQRKEEEPSSSSVFNQNDPWAPTVDF 660 Query: 661 SDFINNETIAGKDLVAWVTAGFLHIPHAEDIPNTVTVGNGVGFFLRPYNFFDEDPSFYSA 720 SDFINNETIAGKDLVAWVTAGFLHIPHAEDIPNTVTVGNGVGFFLRPYNFFDEDPSFYSA Sbjct: 661 SDFINNETIAGKDLVAWVTAGFLHIPHAEDIPNTVTVGNGVGFFLRPYNFFDEDPSFYSA 720 Query: 721 DSIYFRGDQDAGACEVNPLACLPQAAACAPDLPAFSHGGFSHN 763 DSIYFRGDQDAGACEVNPLACLPQAAACAPDLPAFSHGGFSHN Sbjct: 721 DSIYFRGDQDAGACEVNPLACLPQAAACAPDLPAFSHGGFSHN 763 >2PNC-A nrPDB Length = 746 Score = 1063 bits (2750), Expect = 0.0, Method: Composition-based stats. Identities = 602/726 (82%), Positives = 658/726 (90%) Query: 35 PSQLPHCPSVSPSAQPWTHPGQSQLFADLSREELTAVMRFLTQRLGPGLVDAAQARPSDN 94 PS P CPS SPS QPWTHP QSQLFADLSREELT VM FLTQ+LGP LVDAAQARPSDN Sbjct: 18 PSLPPRCPSRSPSDQPWTHPDQSQLFADLSREELTTVMSFLTQQLGPDLVDAAQARPSDN 77 Query: 95 CVFSVELQLPPKAAALAHLDRGSPPPAREALAIVFFGRQPQPNVSELVVGPLPHPSYMRD 154 CVFSVELQLPPKAAALAHLDRGSPPPAREALAIVFFG QPQPNV+ELVVGPLP PSYMRD Sbjct: 78 CVFSVELQLPPKAAALAHLDRGSPPPAREALAIVFFGGQPQPNVTELVVGPLPQPSYMRD 137 Query: 155 VTVERHGGPLPYHRRPVLFQEYLDIDQMIFNRELPQASGLLHHCCFYKHRGRNLVTMTTA 214 VTVERHGGPLPY+RRPVL +EYLDIDQMIFNRELPQA+G+LHHCC YK G+ L+TM +A Sbjct: 138 VTVERHGGPLPYYRRPVLLREYLDIDQMIFNRELPQAAGVLHHCCSYKQGGQKLLTMNSA 197 Query: 215 PRGLQSGDRATWFGLYYNISGAGFFLHHVGLELLVNHKALDPARWTIQKVFYQGRYYDSL 274 PRG+QSGDR+TWFG+YYNI+ G +LH VGLELLV+HKALDPA WT+QKVF+QGRYY++L Sbjct: 198 PRGVQSGDRSTWFGIYYNITKGGPYLHPVGLELLVDHKALDPADWTVQKVFFQGRYYENL 257 Query: 275 AQLEAQFEAGLVNVVLIPDNGTGGSWSLKSPVPPGPAPPLQFYPQGPRFSVQGSRVASSL 334 AQLE QFEAG VNVV+IPD+GTGG WSLKS VPPGP PPLQF+PQGPRFSVQG+RVASSL Sbjct: 258 AQLEEQFEAGQVNVVVIPDDGTGGFWSLKSQVPPGPTPPLQFHPQGPRFSVQGNRVASSL 317 Query: 335 WTFSFGLGAFSGPRIFDVRFQGERLVYEISLQEALAIYGGNSPAAMTTRYVDGGFGMGKY 394 WTFSFGLGAFSGPR+FDVRFQGERL YEISLQEA A+YGGN+PAAM TRY+D GFGMG + Sbjct: 318 WTFSFGLGAFSGPRVFDVRFQGERLAYEISLQEAGAVYGGNTPAAMLTRYMDSGFGMGYF 377 Query: 395 TTPLTRGVDCPYLATYVDWHFLLESQAPKTIRDAFCVFEQNQGLPLRRHHSDLYSHYFGG 454 TPL RGVDCPYLATY+DWHF++ESQ PKT+ DAFCVFEQN+GLPLRRHHSD SHYFGG Sbjct: 378 ATPLIRGVDCPYLATYMDWHFVVESQTPKTLHDAFCVFEQNKGLPLRRHHSDFLSHYFGG 437 Query: 455 LAETVLVVRSMSTLLNYDYVWDTVFHPSGAIEIRFYATGYISSAFLFGATGKYGNQVSEH 514 +A+TVLV RS+ST+LNYDYVWD VF+P+GAIE++ +ATGYISSAFLFGA +YGNQV EH Sbjct: 438 VAQTVLVFRSVSTMLNYDYVWDMVFYPNGAIEVKLHATGYISSAFLFGAARRYGNQVGEH 497 Query: 515 TLGTVHTHSAHFKVDLDVAGLENWVWAEDMVFVPMAVPWSPEHQLQRLQVTRKLLEMEEQ 574 TLG VHTHSAH+KVDLDV GLENWVWAEDM FVP A+PWSPEHQ+QRLQVTRK LE EEQ Sbjct: 498 TLGPVHTHSAHYKVDLDVGGLENWVWAEDMAFVPTAIPWSPEHQIQRLQVTRKQLETEEQ 557 Query: 575 AAFLVGSATPRYLYLASNHSNKWGHPRGYRIQMLSFAGEPLPQNSSMARGFSWERYQLAV 634 AAF +G A+PRYLYLAS SNKWGHPRGYRIQ +SFAG P+PQNS M R FSW RYQLA+ Sbjct: 558 AAFPLGGASPRYLYLASKQSNKWGHPRGYRIQTVSFAGGPMPQNSPMERAFSWGRYQLAI 617 Query: 635 TQRKEEEPSSSSVFNQNDPWAPTVDFSDFINNETIAGKDLVAWVTAGFLHIPHAEDIPNT 694 TQRKE EPSSSSVFNQNDPW PTVDFSDFINNETIAGKDLVAWVTAGFLHIPHAEDIPNT Sbjct: 618 TQRKETEPSSSSVFNQNDPWTPTVDFSDFINNETIAGKDLVAWVTAGFLHIPHAEDIPNT 677 Query: 695 VTVGNGVGFFLRPYNFFDEDPSFYSADSIYFRGDQDAGACEVNPLACLPQAAACAPDLPA 754 VTVGNGVGFFLRPYNFFD++PS SADSIYFR QDAG+CE+NPLACLPQAA CAPDLP Sbjct: 678 VTVGNGVGFFLRPYNFFDQEPSMDSADSIYFREGQDAGSCEINPLACLPQAATCAPDLPV 737 Query: 755 FSHGGF 760 FSHGG+ Sbjct: 738 FSHGGY 743 >3K5T-A nrPDB Length = 731 Score = 889 bits (2298), Expect = 0.0, Method: Composition-based stats. Identities = 293/736 (39%), Positives = 417/736 (56%), Gaps = 38/736 (5%) Query: 50 PWTHPGQSQLFADLSREELTAVMRFLTQRLGPGLVDAAQARPSDNCVFSVELQLPPKAAA 109 P T P ++ +F+DLS +EL AV FL + L ++ + N VF +E+ LP K Sbjct: 3 PGTLPRKAGVFSDLSNQELKAVHSFLWSKKELRLQPSSTTTMAKNTVFLIEMLLPKKYHV 62 Query: 110 LAHLDRGSPPPAREALAIVFFGRQPQPNVSELVVGPLPHPSYMRDVTVERHGGPLPYHRR 169 L LD+G P REA A++FFG Q PNV+E VGPLP P YMR ++ R G + R Sbjct: 63 LRFLDKGERHPVREARAVIFFGDQEHPNVTEFAVGPLPGPCYMRALS-PRPGYQSSWASR 121 Query: 170 PVLFQEYLDIDQMIFNRELPQASGLLHHC-------CFYKHRGRNLVTMTTAPRGLQSGD 222 P+ EY + L +A+ LH F R L APRG+ SG Sbjct: 122 PISTAEY-----ALLYHTLQEATKPLHQFFLNTTGFSFQDCHDRCLAFTDVAPRGVASGQ 176 Query: 223 RATWFGLYYNISGAGFFLHHVGLELLVNHKALDPARWTIQKVFYQGRYYDSLAQLEAQFE 282 R +W + + G +FLH GLELLV+H + D W +++V+Y G++Y S +L ++ Sbjct: 177 RRSWLIIQRYVEG--YFLHPTGLELLVDHGSTDAGHWAVEQVWYNGKFYGSPEELARKYA 234 Query: 283 AGLVNVVLIPDNGTGGSWSLKSPVPP----------GPAP-----PLQFYPQGPRFSVQG 327 G V+VV++ D GG + PP P+P P P GPRF ++G Sbjct: 235 DGEVDVVVLEDPLPGGKGHDSTEEPPLFSSHKPRGDFPSPIHVSGPRLVQPHGPRFRLEG 294 Query: 328 SRVASSLWTFSFGLGAFSGPRIFDVRFQGERLVYEISLQEALAIYGGNSPAAMTTRYVDG 387 + V W+F+F L + SG ++ +V F GER+ YE+S+QEA+A+YGG++PA M T+Y+D Sbjct: 295 NAVLYGGWSFAFRLRSSSGLQVLNVHFGGERIAYEVSVQEAVALYGGHTPAGMQTKYLDV 354 Query: 388 GFGMGKYTTPLTRGVDCPYLATYVDWHFLLESQAPKTIRDAFCVFEQNQGLPLRRHHSDL 447 G+G+G T L G+DCP AT++D ++ P A C+FE G+PLRRH + Sbjct: 355 GWGLGSVTHELAPGIDCPETATFLDTFHYYDADDPVHYPRALCLFEMPTGVPLRRHFNSN 414 Query: 448 YS---HYFGGLAETVLVVRSMSTLLNYDYVWDTVFHPSGAIEIRFYATGYISSAFLFGAT 504 + +++ GL VLV+R+ ST+ NYDY+WD +F+P+G +E + +ATGY+ + F Sbjct: 415 FKGGFNFYAGLKGQVLVLRTTSTVYNYDYIWDFIFYPNGVMEAKMHATGYVHATFYTPEG 474 Query: 505 GKYGNQVSEHTLGTVHTHSAHFKVDLDVAGLENWVWAEDMVFVPMAVPWSPEHQLQRLQV 564 ++G ++ H +G +HTH H++VDLDVAG +N M + PWSP H++ + + Sbjct: 475 LRHGTRLHTHLIGNIHTHLVHYRVDLDVAGTKNSFQTLQMKLENITNPWSPRHRVVQPTL 534 Query: 565 TRKLLEMEEQAAFLVGSATPRYLYLASNHSNKWGHPRGYRIQMLSFAGEPLPQNSSMARG 624 + E QAAF P+YL S N WGH R YR+Q+ S A + LP + Sbjct: 535 EQTQYSWERQAAFRFKRKLPKYLLFTSPQENPWGHKRSYRLQIHSMADQVLPPGWQEEQA 594 Query: 625 FSWERYQLAVTQRKEEEPSSSSVFNQNDPWAPTVDFSDFI-NNETIAGKDLVAWVTAGFL 683 +W RY LAVT+ +E E SSS+++QNDPW P V F F+ NNE I +DLVAWVT GFL Sbjct: 595 ITWARYPLAVTKYRESELCSSSIYHQNDPWDPPVVFEQFLHNNENIENEDLVAWVTVGFL 654 Query: 684 HIPHAEDIPNTVTVGNGVGFFLRPYNFFDEDPSFYSADSIYFRGDQDAGACEVNPLACLP 743 HIPH+EDIPNT T GN VGF LRP+NFF EDPS S D++ +D G V +P Sbjct: 655 HIPHSEDIPNTATPGNSVGFLLRPFNFFPEDPSLASRDTVIV-WPRDNGPNYVQ--RWIP 711 Query: 744 QAAACAPDLPAFSHGG 759 + C+ P FS+ G Sbjct: 712 EDRDCSMP-PPFSYNG 726 >3PGB-A nrPDB Length = 797 Score = 773 bits (1995), Expect = 0.0, Method: Composition-based stats. Identities = 199/701 (28%), Positives = 324/701 (46%), Gaps = 40/701 (5%) Query: 56 QSQLFADLSREELTAVMRFLTQRLGPGLVDAAQARPSDNCVFSVELQLPPKAAALAHLDR 115 + ++ L+ +E V ++L R L A DN + +EL P K+ A+ +LD Sbjct: 64 KENVWYGLTDDETADVAKWLFGRPELNLTTTENAGEWDNTIALIELHRPNKSEAIPYLDG 123 Query: 116 GSPPPAREALAIVFFGRQPQPNVSELVVGPLPHPSYMRDVTVERHGGPL--PYHRRPVLF 173 P P R A + P ++++VGPLP V+ PL PY R+ Sbjct: 124 SGPAPTRHAHVRLNNRATTDPYFADILVGPLP-------VSNATTWEPLEFPYTRKTQGQ 176 Query: 174 QEYLDID-QMIFNRELPQASGLLHHCCFYKHRGR--NLVTMTTAPRGL----QSGDRATW 226 ++ D + +++ L + S + G L T G+ Q R Sbjct: 177 VRNVEPDGETVYSEWLFKISASIADITLDLWNGTALGLENDTLDIWGIDPLWQDDGRIIR 236 Query: 227 FGLYYNISGAGF---FLHHVGLELLVNHKALDPARWTIQKVFYQGRYYDSLAQL-EAQFE 282 + +++N++ F L +GL L + DP++W + Y +Y++ + +A + Sbjct: 237 WDMFWNMADDEFDSETLLPLGLYLKSDVTGRDPSQWKLLGWMYNDIFYETTEEFRKAYWS 296 Query: 283 AGLVNVVLIPDNGTGGSWS---LKSPVPPG--PAPPLQFYPQGPRFSVQGSRVASSLWTF 337 G V + G+W+ + PVPP PP+ P G R+SV R + F Sbjct: 297 PGFVKL----KPNVDGAWAHTEQRGPVPPQDRKQPPVMIAPDGARYSVDAERKYVTWMDF 352 Query: 338 SF--GLGAFSGPRIFDVRFQGERLVYEISLQEALAIYGGNSPAAMTTRYVDGGFGMGKYT 395 SF +G +FD++++G+R++YE+ LQEALA Y N P + Y+D +G G Y Sbjct: 353 SFYIAFNRDTGLSLFDIKYKGQRVLYELGLQEALAHYAANDPVQSSVAYLDSYYGFGPYA 412 Query: 396 TPLTRGVDCPYLATYVDWHFLLESQAPKTIRDAFCVFEQNQGLPLRRHHSDLYSHYFGGL 455 L +G DCP A+Y++ F + + T D+ C+FE + P+ RH + S + Sbjct: 413 FELLKGYDCPSYASYLNTSFYKDEET-HTHVDSLCLFEFDADYPMARHST---SEFVSVT 468 Query: 456 AETVLVVRSMSTLLNYDYVWDTVFHPSGAIEIRFYATGYISSAFLFGATGKYGNQVSEHT 515 +RS+ST+ NYDY++ FH G I + A+GYI SA+ + +G Q+ + Sbjct: 469 KNVYFTLRSVSTIGNYDYMFSYNFHMDGTIGVEVRASGYIQSAY-YANNQDFGYQIHDSL 527 Query: 516 LGTVHTHSAHFKVDLDVAGLENWVWAEDMVFVPMAVPWSPEHQLQRLQVTRKLLEMEEQA 575 G++H H +FK D D+ G N + +V V WS +Q+ R + E++A Sbjct: 528 SGSMHDHVLNFKADFDILGPNNTIELVSVVPVTKQFSWSGNKTRNTMQLGRSFIHSEDEA 587 Query: 576 AFLVGSATPRYLYL-ASNHSNKWGHPRGYRIQMLSFAGEP-LPQNSSMARGFSWERYQLA 633 G L++ + NK+G PRGYRI + + +S++ W Y + Sbjct: 588 RLNWGFNGQTQLHVVNQDKPNKFGEPRGYRILPSAGTAHLTVLNSSNLVHAAHWAEYDVQ 647 Query: 634 VTQRKEEEPSSSSVFNQNDPWAPTVDFSDFINNETIAGKDLVAWVTAGFLHIPHAEDIPN 693 VT++ + EP+S+ +N D P VDFS F N E++ DLV W+ G H+PH D+PN Sbjct: 648 VTRQHDFEPTSAHPYNSQDIHNPPVDFSTFFNGESLNQTDLVVWLNLGMHHVPHTGDLPN 707 Query: 694 TVTVGNGVGFFLRPYNFFDEDPSFYSADSIYFRGDQDAGAC 734 TV G P N+ DPS + + + R D GA Sbjct: 708 TVFTTAHSGVAFTPLNYLPGDPSRETVNMV--RVDYSDGAA 746 >1RKY-A nrPDB Length = 747 Score = 718 bits (1854), Expect = 0.0, Method: Composition-based stats. Identities = 191/710 (26%), Positives = 307/710 (43%), Gaps = 59/710 (8%) Query: 56 QSQLFADLSREELTAVMRFLTQRLGPGLVDAAQARPSDNCVFSVELQLPPKAAALAHLDR 115 ++ ++ L++EE+ V+ L + + +A N V +E P K AL +LD Sbjct: 17 KTNIWTSLAKEEVQEVLDLLHSTY--NITEVTKADFFSNYVLWIETLKPNKTEALTYLDE 74 Query: 116 GSPPPAREALAIVFFGRQPQPNVSELVVGPLPHPSYMRDVTVERHGGPLPYHRRPVLFQE 175 P R A +V+FG + EL VGPLP V+ E PL ++ + Sbjct: 75 DGDLPPRNARTVVYFGEGEEGYFEELKVGPLP-------VSDETTIEPLSFYNTNGKSKL 127 Query: 176 YLDIDQMIFNRELPQASGLLHHCCFYKHRGRNLVTMTTAPRGL---------------QS 220 ++ + + ++S L ++ N M GL Q Sbjct: 128 PFEVGHLDRIKSAAKSSFL--------NKNLNTTIMRDVLEGLIGVPYEDMGCHSAAPQL 179 Query: 221 GDRATWFGLYY-----NISGAGFFLHHVGLELLVNHKALDPARWTIQKVFYQGRYYDSLA 275 D AT + Y N L G + D ++W + + Y + Y S Sbjct: 180 HDPATGATVDYGTCNINTENDAENLVPTGFFFKFDMTGRDVSQWKMLEYIYNNKVYTSAE 239 Query: 276 QL-EAQFEAGLVNVVLIPDNGTGGSWSLKSPVPPGP-------APPLQFYPQGPRFSVQG 327 +L EA + V + I + W++ P P P+G R++ G Sbjct: 240 ELYEAMQKDDFVTLPKIDVDNLD--WTVIQRNDSAPVRHLDDRKSPRLVEPEGRRWAYDG 297 Query: 328 SRVASSL--WTFSFGLGAFSGPRIFDVRFQGERLVYEISLQEALAIYGGNSPAAMTTRYV 385 S W F +G +D+ F+GER+VYE+SLQE +A YG + P T Y Sbjct: 298 DEEYFSWMDWGFYTSWSRDTGISFYDITFKGERIVYELSLQELIAEYGSDDPFNQHTFYS 357 Query: 386 DGGFGMGKYTTPLTRGVDCPYLATYVDWH-FLLESQAPKTIRDAFCVFEQNQGLPLRRHH 444 D +G+G L G DCP A Y F + +T+ ++CVFE + L RH Sbjct: 358 DISYGVGNRF-SLVPGYDCPSTAGYFTTDTFEYDEFYNRTL--SYCVFENQEDYSLLRHT 414 Query: 445 SDLYSHYFGGLAETVLVVRSMSTLLNYDYVWDTVFHPSGAIEIRFYATGYISSAFLFGAT 504 YS L VR +ST+ NYDY + F G +E+ A GYI + + T Sbjct: 415 GASYS---AITQNPTLNVRFISTIGNYDYNFLYKFFLDGTLEVSVRAAGYIQAGYWNPET 471 Query: 505 -GKYGNQVSEHTLGTVHTHSAHFKVDLDVAGLENWVWAEDMVFVPMAVPWSPEHQLQRLQ 563 YG ++ + G+ H H ++KVDLDV G +N M V + PW+P Q Sbjct: 472 SAPYGLKIHDVLSGSFHDHVLNYKVDLDVGGTKNRASQYVMKDVDVEYPWAPGTVYNTKQ 531 Query: 564 VTRKLLEMEEQAAFLV-GSATPRYLYLASNHSNKWGHPRGYRIQMLSFAGEPLPQNS-SM 621 + R++ E E+ + L ++ +N +G+PR Y I + +NS S Sbjct: 532 IAREVFENEDFNGINWPENGQGILLIESAEETNSFGNPRAYNIMPGGGGVHRIVKNSRSG 591 Query: 622 ARGFSWERYQLAVTQRKEEEPSSSSVFNQNDPWAPTVDFSDFINNETIAGKDLVAWVTAG 681 +W R L +T+ K+ E SS+ N N + P V+F+ F+++E++ G+D+VAWV G Sbjct: 592 PETQNWARSNLFLTKHKDTELRSSTALNTNALYDPPVNFNAFLDDESLDGEDIVAWVNLG 651 Query: 682 FLHIPHAEDIPNTVTVGNGVGFFLRPYNFFDEDPSFYSADSIYFRGDQDA 731 H+P++ D+PNT+ F L P+N+FD + S + +++ D + Sbjct: 652 LHHLPNSNDLPNTIFSTAHASFMLTPFNYFDSENSRDTTQQVFYTYDDET 701 >1D6Z-A nrPDB Length = 727 Score = 488 bits (1256), Expect = e-138, Method: Composition-based stats. Identities = 162/656 (24%), Positives = 257/656 (39%), Gaps = 73/656 (11%) Query: 87 AQARPSDNCVFS-VELQLPPKAAALAHLDRGSPP-PAREALAIVFFGRQPQPNVSELVVG 144 A A N F+ + L P K A A P R+A I+ G+ V +L Sbjct: 113 ASADFKPNTRFTEISLLPPDKEAVWAFALENKPVDQPRKADVIMLDGKHIIEAVVDLQNN 172 Query: 145 PLPHPSYMRDVTVERHGGPLPYHRRPVLFQEYLDIDQMIFNRELPQASGLLHHCCFYKHR 204 L P+ VL ++ + +I N E A+ K Sbjct: 173 KL------------LSWQPIKDAHGMVLLDDFASVQNIINNSEEFAAAVKKRGITDAKKV 220 Query: 205 GRNLVTMT--TAPRGLQSGDRATWFGLYYNISGAGFFLHHVGLELLVNHKALDPARWTIQ 262 +T+ GL+ R Y ++ ++ H + + V +D + I Sbjct: 221 ITTPLTVGYFDGKDGLKQDARLLKVISYLDVGDGNYWAHPIENLVAV----VDLEQKKIV 276 Query: 263 KVFYQGRYYDSLAQLEAQFEAGLVNVVLIPDNGTGGSWSLKSPVPPGPAPPLQFYPQGPR 322 K+ E G ++P T + + V P P P+G Sbjct: 277 KI-----------------EEG----PVVPVPMTARPFDGRDRVAPAVKPMQIIEPEGKN 315 Query: 323 FSVQGSRVASSLWTFSFGLGAFSGPRIFDVRFQG----ERLVYEISLQEALAIYGGNSPA 378 +++ G + W F + + GP I V + +++YE SL + YG Sbjct: 316 YTITGDMIHWRNWDFHLSMNSRVGPMISTVTYNDNGTKRKVMYEGSLGGMIVPYGDPDIG 375 Query: 379 AMTTRYVDGG-FGMGKYTTPLTRGVDCPYLATYVDWHFLLESQAPKTIRDAFCVFEQNQG 437 Y+D G +GMG T+P+ RG D P A ++ + P I A VFE+ G Sbjct: 376 WYFKAYLDSGDYGMGTLTSPIARGKDAPSNAVLLNETIADYTGVPMEIPRAIAVFERYAG 435 Query: 438 LPLRRHHSDLYSHYFGGLAETVLVVRSMSTLLNYDYVWDTVFHPSGAIEIRFYATGY--- 494 P +H + E LVVR +ST+ NYDY++D +FH +G I I ATG Sbjct: 436 -PEYKHQEMGQPNVSTERRE--LVVRWISTVGNYDYIFDWIFHENGTIGIDAGATGIEAV 492 Query: 495 --ISSAFLFGATGK----YGNQVSEHTLGTVHTHSAHFKVDLDVAGLENWVWAEDMVFVP 548 + + + T K YG + + +GT H H +F++DLDV G N + A D V P Sbjct: 493 KGVKAKTMHDETAKDDTRYGTLIDHNIVGTTHQHIYNFRLDLDVDGENNSLVAMDPVVKP 552 Query: 549 MAVPWSPEHQLQRLQVTRKLLEMEEQAAFLVGSATPRYLYLASNHSNKWGHPRGYRIQML 608 + + +QV + + E+ AA T R L N N+ G+P Y+I Sbjct: 553 NT---AGGPRTSTMQVNQYNIGNEQDAAQKFDPGTIRLLS-NPNKENRMGNPVSYQIIPY 608 Query: 609 SFAGEPLPQNSSMA------RGFSWERYQLAVTQRKEEEPSSSSVF-NQNDPWAPTVDFS 661 + P+ + + A S+ QL VT+ E + N++ +S Sbjct: 609 AGGTHPVAKGAQFAPDEWIYHRLSFMDKQLWVTRYHPGERFPEGKYPNRSTHDTGLGQYS 668 Query: 662 DFINNETIAGKDLVAWVTAGFLHIPHAEDIPNTVTVGNGVGFFLRPYNFFDEDPSF 717 +NE++ D V W+T G H+ AE+ P + V L+P+NFFDE P+ Sbjct: 669 K--DNESLDNTDAVVWMTTGTTHVARAEEWP--IMPTEWVHTLLKPWNFFDETPTL 720 >2CG0-A nrPDB Length = 646 Score = 479 bits (1233), Expect = e-135, Method: Composition-based stats. Identities = 119/465 (25%), Positives = 196/465 (42%), Gaps = 22/465 (4%) Query: 286 VNVVLIPDNGTGGSWS---LKSPVPPGPAPPLQFYPQGPRFSVQG-SRVASSLWTFSFGL 341 ++ + P G+++ L P+ P P+GP F+V G + + W+ G Sbjct: 188 IDTGVFPVPAEHGNYTDPELTGPLRTTQKPISITQPEGPSFTVTGGNHIEWEKWSLDVGF 247 Query: 342 GAFSGPRIFDVRFQG----ERLVYEISLQEALAIYGGNSPAAMTTRYVDGG-FGMGKYTT 396 G + ++ F+ ++ S+ E + YG SP Y D G + +G+Y Sbjct: 248 DVREGVVLHNIAFRDGDRLRPIINRASIAEMVVPYGDPSPIRSWQNYFDTGEYLVGQYAN 307 Query: 397 PLTRGVDCPYLATYVDWHFLLESQAPKTIRDAFCVFEQNQGLPLRRHHSDLYSHYFGGLA 456 L G DC TY+ P+ IR+ C+ E++ G+ + HSDL+S Sbjct: 308 SLELGCDCLGDITYLSPVISDAFGNPREIRNGICMHEEDWGILAK--HSDLWSGINYTRR 365 Query: 457 ETVLVVRSMSTLLNYDYVWDTVFHPSGAIEIRFYATGYI-SSAFLFGATGKYGNQVSEHT 515 +V+ +T+ NYDY + + G IE ATG + +SAF G + +Q++ Sbjct: 366 NRRMVISFFTTIGNYDYGFYWYLYLDGTIEFEAKATGVVFTSAFPEGGSDNI-SQLAPGL 424 Query: 516 LGTVHTHSAHFKVDLDVAGLENWVWAEDMVFVPMAVPWSPEHQLQRLQVTRKLLEMEEQA 575 H H ++D+ + G N V ED+V M + R R +L E +A Sbjct: 425 GAPFHQHIFSARLDMAIDGFTNRVEEEDVVRQTMGPGNERGNAFSR---KRTVLTRESEA 481 Query: 576 AFLVGSATPRYLYLASNHS-NKWGHPRGYRIQMLSFAGEPLPQNSSMARGFSWERYQLAV 634 + T R +++ S N+ P GY++ + SS+AR ++ L V Sbjct: 482 VREADARTGRTWIISNPESKNRLNEPVGYKLHAHNQPTLLADPGSSIARRAAFATKDLWV 541 Query: 635 TQRKEEEPSSSSVF-NQNDPWAPTVDFSDFINNETIAGKDLVAWVTAGFLHIPHAEDIPN 693 T+ ++E + F NQ+ A + + I G+D+V W T G H P ED P Sbjct: 542 TRYADDERYPTGDFVNQHSGGAGLPSY--IAQDRDIDGQDIVVWHTFGLTHFPRVEDWP- 598 Query: 694 TVTVGNGVGFFLRPYNFFDEDPSFYSADSIYFRGDQDAGACEVNP 738 + + VGF LRP FFD P + G G+ +P Sbjct: 599 -IMPVDTVGFKLRPEGFFDRSPVLDVPANPSQSGSHCHGSNWSHP 642 >3NBJ-A nrPDB Length = 692 Score = 472 bits (1214), Expect = e-133, Method: Composition-based stats. Identities = 135/642 (21%), Positives = 233/642 (36%), Gaps = 61/642 (9%) Query: 99 VELQLPPKAAALAHLDRGSPPPAREALAIVFFGRQPQPNVSELVVGPLPHPSYMRDVTVE 158 V L+ P + A + ++G P P R A ++ +P V E +V L S + +E Sbjct: 54 VTLREPARKAYIQWKEQGGPLPPRLAYYVIL--EAGKPGVKEGLVD-LASLSVIETRALE 110 Query: 159 RHGGPLPYHRRPVLFQEYL-DIDQMIFNRELPQASGLLHHCCFYKHRGRNLVTMTTAPRG 217 +P+L E L +++I N ++ C + + P Sbjct: 111 TV--------QPILTVEDLCSTEEVIRND-----PAVIEQCVLSGIPANEMHKVYCDPWT 157 Query: 218 LQSGDR-------ATWFGLYYNISGAGFFLHHVGLELLVNHKALDPARWTIQKVFYQGRY 270 + +R Y + + H + +V+ + + Sbjct: 158 IGYDERWGTGKRLQQALVYYRSDEDDSQYSHPLDFCPIVDTEEKKV------------IF 205 Query: 271 YDSLAQLEAQFEAGLVNVVLIPDNGTGGSWSLKSPVPPGPAPPLQFYPQGPRFSVQGSRV 330 D + + N P + +++ P P P+G F + G+ + Sbjct: 206 IDIPNRRRKVSKHKHANFY--PKHMIEKVGAMRPEAP----PINVTQPEGVSFKMTGNVM 259 Query: 331 ASSLWTFSFGLGAFSGPRIFDVRFQGERLV----YEISLQEALAIYGGNSPAAMTTRYVD 386 S + F G G + DV + V + ISL E + +G +D Sbjct: 260 EWSNFKFHIGFNYREGIVLSDVSYNDHGNVRPIFHRISLSEMIVPFGSPEFPHQRKHALD 319 Query: 387 GG-FGMGKYTTPLTRGVDCPYLATYVDWHFLLESQAPKTIRDAFCVFEQNQGLPLRRHHS 445 G +G G T PL+ G DC + Y+D HF + P T+++A C+ E++ GL + HS Sbjct: 320 IGEYGAGYMTNPLSLGCDCKGVIHYLDAHFSDRAGDPITVKNAVCIHEEDDGLLFK--HS 377 Query: 446 DLYSHYFGG--LAETVLVVRSMSTLLNYDYVWDTVFHPSGAIEIRFYATGYISSAFLFG- 502 D ++ T LVV + T N +Y VF GAI + TG +++ L Sbjct: 378 DFRDNFATSLVTRATKLVVSQIFTAANXEYCLYWVFMQDGAIRLDIRLTGILNTYILGDD 437 Query: 503 -ATGKYGNQVSEHTLGTVHTHSAHFKVDLDVAGLENWVWAEDMVFVPMAVPWSPEHQLQR 561 G +G +V + H H ++D + G N A D P + SPE+ Sbjct: 438 EEAGPWGTRVYPNVNAHNHQHLFSLRIDPRIDGDGNSAAACDAKSSPYPLG-SPENMYGN 496 Query: 562 LQV-TRKLLEMEEQAAFLVGSATPR-YLYLASNHSNKW-GHPRGYRIQMLSFAGEPLPQN 618 + + + + SAT R + N N + G P Y++ + Sbjct: 497 AFYSEKTTFKTVKDSLTNYESATGRSWDIFNPNKVNPYSGKPPSYKLVSTQCPPLLAKEG 556 Query: 619 SSMARGFSWERYQLAVTQRKEEEPSSS--SVFNQNDPWAPTVDFSDFINNETIAGKDLVA 676 S +A+ W + + V K+ S V + + +E I D++ Sbjct: 557 SLVAKRAPWASHSVNVVPYKDNRLYPSGDHVPQWSGDGVRGMREWIGDGSENIDNTDILF 616 Query: 677 WVTAGFLHIPHAEDIPNTVTVGNGVGFFLRPYNFFDEDPSFY 718 + T G H P ED P + + LRP +FF E+P Sbjct: 617 FHTFGITHFPAPEDFP--LXPAEPITLMLRPRHFFTENPGLD 656 >3LOY-A nrPDB Length = 633 Score = 465 bits (1195), Expect = e-131, Method: Composition-based stats. Identities = 138/629 (21%), Positives = 233/629 (37%), Gaps = 63/629 (10%) Query: 134 PQPNVSELVVGPLPHPSYMRDVTVERHGGPLPYHRRPVLFQEYLDIDQMIFNRELPQASG 193 +P+ ++ P +R + ER G PLP+ R + Y I + F + L S Sbjct: 27 ERPHFIQIDRLDPPKKDMIRYLEAERTGKPLPHISR--MTYVYYYIG-LDFYKALVNVSY 83 Query: 194 LLHHCCFYKHR----GRNLVTMTTAPRGLQSGDRATWFGLYYNISGAGFFLHHVGLELLV 249 H K G + L + + + ++ Sbjct: 84 G-HIITNQKQPKGVIGPLIAEDIQEIEELATTHPIVKAEI-------EKLKLPPHVRVVC 135 Query: 250 N--HKALDPA--RWTIQKVFY-------QGRYYDSLAQLEAQFEAGLVNVVLIPDNGTGG 298 + D R IQ Y + +Y + FE L + D GG Sbjct: 136 DPWMNGTDSKEDRMLIQCYMYLASAAHPESNHYSLPLKFSPVFEC-LTKKFVRMDYLPGG 194 Query: 299 S---------WS----------LKSPVPPGPAPPLQFYPQGPRFSVQGSRVASSLWTFSF 339 + W L P + P+GP F+V G +++ W F Sbjct: 195 ADETVTETQAWDEFPFVEYHPDLNGETIVPLKPLIVQQPEGPSFNVDGHKISWQGWEFFV 254 Query: 340 GLGAFSGPRIFDVRFQGERLVYEISLQEALAIYGGN-SPAAMTTRYVDGGFGMGKYTTPL 398 G I+D+ F+G +VY +SL E YG +P + G G G L Sbjct: 255 IPTVREGFAIYDIHFKGRSVVYRLSLSEMTVPYGDPRAPFHRKQAFDLGDCGFGATGNSL 314 Query: 399 TRGVDCPYLATYVDWHFLLESQAPKTIRDAFCVFEQNQGLPLRRHHSDLYSHYFGGLAET 458 G DC + Y+D + + I + C+ EQ+ GL + H++ ++ Sbjct: 315 ALGCDCLGVIKYMDCRRVNTNGDSVLIPNTVCLHEQDGGLLYK--HTNYRTNVPVIARRR 372 Query: 459 VLVVRSMSTLLNYDYVWDTVFHPSGAIEIRFYATGYISSAFL-FGATGKYGNQVSEHTLG 517 VV++++T+ NY+Y+ + +F +G I I ATG +S+ L T +G V + Sbjct: 373 EFVVQTIATVANYEYMLNIIFDQAGEIRIHVRATGILSTMPLDKDVTVPWGTNVGPRVMA 432 Query: 518 TVHTHSAHFKVDLDVAGLENWVWAEDMVFVPMAVPWSPEHQLQRLQVTRKLLEME---EQ 574 H H F++D V G EN V +D++ + +P + R ++E EQ Sbjct: 433 AYHQHMLSFRIDPAVDGYENTVVFDDVIRMEKNTKLNPYN--VGFVTERTVVEKPGYVEQ 490 Query: 575 AAFLVGSATPRYLYLASNHSNKWG-HPRGYRIQMLSFAGEPLPQNSSMARGFSWERYQLA 633 + F S Y + N N P Y+I M + ++S + + Q+ Sbjct: 491 SPFTNRS----YKIINENKINPISKKPVAYKIMMPARQMLLADEDSYNNKRAQFATQQVW 546 Query: 634 VTQRKEEEPSSSSVFNQNDPWAPTVDFSDFINNETIAGKDLVAWVTAGFLHIPHAEDIPN 693 VT+ ++ E ++ F + +E + + V W T GF HIP ED P Sbjct: 547 VTKYRDNELYAAGEFTNQSQTDTGLGVWA-RRDENVRNDNPVVWATLGFTHIPRVEDFPV 605 Query: 694 TVTVGNGVGFFLRPYNFFDEDPSFYSADS 722 + + L P+ FFD++P+ S Sbjct: 606 MPVEAHEIA--LVPFGFFDKNPALSVPQS 632 >1KSI-A nrPDB Length = 642 Score = 449 bits (1156), Expect = e-126, Method: Composition-based stats. Identities = 104/446 (23%), Positives = 174/446 (39%), Gaps = 29/446 (6%) Query: 302 LKSPVPPGPAPPLQFYPQGPRFSVQGSRVASSLWTFSFGLGAFSGP-----RIFDV-RFQ 355 P P PQGP F + G V+ + W F G +G I+D+ + + Sbjct: 205 QSPPFGPKQHSLTSHQPQGPGFQINGHSVSWANWKFHIGFDVRAGIVISLASIYDLEKHK 264 Query: 356 GERLVYEISLQEALAIYGGNSPAAMTTRYVDGG-FGMGKYTTPLTRGVDCPYLATYVDWH 414 R++Y+ + E Y + + D G FG G T L DCP A ++D + Sbjct: 265 SRRVLYKGYISELFVPYQDPTEEFYFKTFFDSGEFGFGLSTVSLIPNRDCPPHAQFIDTY 324 Query: 415 FLLESQAPKTIRDAFCVFEQNQGLPLRRHHSDLYSHYFG-GLAETVLVVRSMSTLLNYDY 473 + P +++A CVFEQ + R + + + E L+VR++ T+ NYD Sbjct: 325 VHSANGTPILLKNAICVFEQYGNIMWRHTENGIPNESIEESRTEVNLIVRTIVTVGNYDN 384 Query: 474 VWDTVFHPSGAIEIRFYATGYISSAFLFGATGKYGNQVSE---------HTLGTVHTHSA 524 V D F SG+I+ +G + + G K+ +++ E +++G H H Sbjct: 385 VIDWEFKASGSIKPSIALSGILE---IKGTNIKHKDEIKEDLHGKLVSANSIGIYHDHFY 441 Query: 525 HFKVDLDVAGLENWVWAEDMVFVPMAVPWSPEHQLQRLQVTRKLLEMEEQAAFLVGSATP 584 + +D D+ G N E + + + + + E A +G A Sbjct: 442 IYYLDFDIDGTHNSF--EKTSLKTVRIKDGSSKRKSYWTTETQTAKTESDAKITIGLAPA 499 Query: 585 RYLYLASNHSNKWGHPRGYRIQMLSFAGEPL--PQNSSMARGFSWERYQLAVTQRKEEEP 642 + + N G+ GYR+ + + PL + RG + Y + VT E Sbjct: 500 ELVVVNPNIKTAVGNEVGYRL-IPAIPAHPLLTEDDYPQIRGA-FTNYNVWVTAYNRTEK 557 Query: 643 SSSSVFNQNDPWAPTVDFSDFINNETIAGKDLVAWVTAGFLHIPHAEDIPNTVTVGNGVG 702 + ++ + T+ N E I KD+V W G H+P ED P + Sbjct: 558 WAGGLYVDHSRGDDTLAVWTKQNRE-IVNKDIVMWHVVGIHHVPAQEDFPIMPLL--STS 614 Query: 703 FFLRPYNFFDEDPSFYSADSIYFRGD 728 F LRP NFF+ +P + Sbjct: 615 FELRPTNFFERNPVLKTLSPRDVAWP 640 >2GVU-A nrPDB Length = 314 Score = 34.0 bits (76), Expect = 0.26, Method: Composition-based stats. Identities = 18/52 (34%), Positives = 24/52 (46%), Gaps = 3/52 (5%) Query: 29 GGDGGEPSQLPHCPSVSPSAQPWTHPGQSQLFADLSREELTAVMRFLTQRLG 80 G DGG+P CP PS + P +F ++ E AV +F QR G Sbjct: 253 GPDGGQPKMRIRCPFEKPSNLHFK-PQTKTIF--VTEHENNAVWKFEWQRNG 301 >4C9T-A nrPDB Length = 282 Score = 32.8 bits (73), Expect = 0.56, Method: Composition-based stats. Identities = 34/204 (16%), Positives = 61/204 (29%), Gaps = 18/204 (8%) Query: 62 DLSREELTAVMRFLTQRLGPGLVDAAQARPSDNCVFSVELQLPPKAAALAHLDRGSPPPA 121 +R +LT +L L P L A A V + Q+P A A +D A Sbjct: 64 GYARMQLTE-HHWLVSDLDPRLEIKAIAETFPMDVLVWQGQIPAAAHTDAQIDSDGD--A 120 Query: 122 REALAIVFFGRQPQPNVSELVVGPLPHPSYMRDVTVERHGGPLPYHRRPVLFQEYLDIDQ 181 A P + LP R +R + +D+ Sbjct: 121 GNAARKSNNAEG-NPFIFAF----LPMWWEKDLKGKGRTIEDGANYRFNMTIGFPEGVDK 175 Query: 182 MIFNRELPQASGLLHHCCFYKHRGRNLVTMTTAPRGLQSGDRATWFGLYYNISGAGFFLH 241 + L + + + +A + +G W + + +G++ Sbjct: 176 AEGEKWLFEKVVPILQAAPE-----CTRVLASAVKKDINGCVMDWVLEIWFENQSGWYKV 230 Query: 242 HVGLELLVNHKALDPARWTIQKVF 265 ++ + KAL+ W Q F Sbjct: 231 -----MVDDMKALEKPSWAQQDAF 249 >4Q2R-A nrPDB Length = 381 Score = 32.4 bits (72), Expect = 0.68, Method: Composition-based stats. Identities = 12/72 (16%), Positives = 25/72 (34%), Gaps = 4/72 (5%) Query: 678 VTAGFLHIPHAEDIPNTVTVGNGVGFFLRPYNFFD----EDPSFYSADSIYFRGDQDAGA 733 L P ++ P+ N + L P + + PS ++ D + G + G Sbjct: 7 HNTLKLRFPAEDEFPDLSGHNNHMAKVLTPELYAELRAKSTPSGFTVDDVIQTGVDNPGH 66 Query: 734 CEVNPLACLPQA 745 + + C+ Sbjct: 67 PYIMTVGCVAGD 78 >3PKO-A nrPDB Length = 334 Score = 30.9 bits (68), Expect = 2.3, Method: Composition-based stats. Identities = 10/99 (10%), Positives = 29/99 (29%), Gaps = 14/99 (14%) Query: 444 HSDLYSHYFG--GLAETVLVVRSMSTLLNYDYVWDTVFHPSGAIEIRFYATGYISSAFLF 501 H D+ G+ + + + D+++ F + S Sbjct: 95 HDDVIDDSPTRRGVRTIQMTYGQRNAIYAGDFMFTVYFDQ------------VLKSTTDR 142 Query: 502 GATGKYGNQVSEHTLGTVHTHSAHFKVDLDVAGLENWVW 540 + + + G +H +++ D+ + N + Sbjct: 143 SLIQNHIDAMHRILQGELHQMDLNYREDITLDAYLNEIA 181 >3IHG-A nrPDB Length = 535 Score = 30.1 bits (66), Expect = 3.7, Method: Composition-based stats. Identities = 16/77 (20%), Positives = 28/77 (36%), Gaps = 6/77 (7%) Query: 335 WTFSFGLGAFSGPRIFDVRFQGERLVYEISLQEALAIYGGNSPAAMTTRYVDG-GF---- 389 W + L +G + D ++ E+ + EALAIY M + G+ Sbjct: 333 WKLAAVLQGQAGAGLLDTYEDERKVAAELVVAEALAIYAQRMAPHMAEVWDKSVGYPETL 392 Query: 390 -GMGKYTTPLTRGVDCP 405 G ++ + D P Sbjct: 393 LGFRYRSSAVLATDDDP 409 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.305 0.126 0.334 Lambda K H 0.267 0.0388 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 28,791,105 Number of Sequences: 36641 Number of extensions: 1158430 Number of successful extensions: 2861 Number of sequences better than 10.0: 18 Number of HSP's better than 10.0 without gapping: 22 Number of HSP's successfully gapped in prelim test: 10 Number of HSP's that attempted gapping in prelim test: 2722 Number of HSP's gapped (non-prelim): 44 length of query: 763 length of database: 10,336,785 effective HSP length: 105 effective length of query: 658 effective length of database: 6,489,480 effective search space: 4270077840 effective search space used: 4270077840 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.1 bits) S2: 63 (29.0 bits)