BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q16836 (314 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 1F14-A nrPDB 610 e-175 3HDH-A nrPDB 573 e-164 4J0E-A nrPDB 303 8e-83 4KUG-A nrPDB 242 1e-64 6ACQ-A nrPDB 234 4e-62 4PZE-A nrPDB 221 4e-58 3MOG-A nrPDB 211 3e-55 6HRD-A nrPDB 210 6e-55 2WTB-A nrPDB 162 2e-40 4DYD-A nrPDB 160 9e-40 5ZRV-A nrPDB 159 1e-39 4B3J-A nrPDB 157 7e-39 4OM8-A nrPDB 146 1e-35 3ZWA-A nrPDB 143 9e-35 1ZCJ-A nrPDB 143 1e-34 2D3T-A nrPDB 142 1e-34 6IUM-B nrPDB 141 5e-34 3K6J-A nrPDB 129 1e-30 1ZEJ-A nrPDB 123 1e-28 3F3S-A nrPDB 90 1e-18 3ADO-A nrPDB 87 1e-17 3CTV-A nrPDB 46 3e-05 5ER0-A nrPDB 37 0.008 2CDU-A nrPDB 34 0.067 3KVE-A nrPDB 33 0.11 1F8S-A nrPDB 33 0.13 2BC1-A nrPDB 33 0.14 4MO2-B nrPDB 33 0.21 1REO-A nrPDB 32 0.24 3KYB-A nrPDB 32 0.43 2EL7-A nrPDB 31 0.61 5X1Y-B nrPDB 31 0.84 3CGD-A nrPDB 31 0.90 1PS9-A nrPDB 30 1.7 2EQ6-A nrPDB 29 2.3 2NQR-A nrPDB 29 2.6 3ICS-A nrPDB 28 3.8 3FG2-P nrPDB 28 4.1 5Y77-A nrPDB 28 4.3 4FS8-A nrPDB 28 4.8 2UYY-A nrPDB 28 6.4 1LSS-A nrPDB 27 7.9 3KKJ-A nrPDB 27 9.1 >1F14-A nrPDB Length = 310 Score = 610 bits (1573), Expect = e-175, Method: Compositional matrix adjust. Identities = 300/302 (99%), Positives = 300/302 (99%) Query: 13 SSSSTASASAKKIIVKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEE 72 SSSSTASASAKKIIVKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEE Sbjct: 1 SSSSTASASAKKIIVKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEE 60 Query: 73 SLRKVAKKKFAENLKAGDEFVEKTLSTIATSTDAASVVHSTDLVVEAIVENLKVKNELFK 132 SLRKVAKKKFAEN KAGDE VEKTLSTIATSTDAASVVHSTDLVVEAIVENLKVKNELFK Sbjct: 61 SLRKVAKKKFAENPKAGDECVEKTLSTIATSTDAASVVHSTDLVVEAIVENLKVKNELFK 120 Query: 133 RLDKFAAEHTIFASNTSSLQITSIANATTRQDRFAGLHFFNPVPVMKLVEVIKTPMTSQK 192 RLDKFAAEHTIFASNTSSLQITSIANATTRQDRFAGLHFFNPVPVMKLVEVIKTPMTSQK Sbjct: 121 RLDKFAAEHTIFASNTSSLQITSIANATTRQDRFAGLHFFNPVPVMKLVEVIKTPMTSQK 180 Query: 193 TFESLVDFSKALGKHPVSCKDTPGFIVNRLLVPYLMEAIRLYERGDASKEDIDTAMKLGA 252 TFESLVDFSKALGKHPVSCKDTPGFIVNRLLVPYLMEAIRLYERGDASKEDIDTAMKLGA Sbjct: 181 TFESLVDFSKALGKHPVSCKDTPGFIVNRLLVPYLMEAIRLYERGDASKEDIDTAMKLGA 240 Query: 253 GYPMGPFELLDYVGLDTTKFIVDGWHEMDAENPLHQPSPSLNKLVAENKFGKKTGEGFYK 312 GYPMGPFELLDYVGLDTTKFIVDGWHEMDAENPLHQPSPSLNKLVAENKFGKKTGEGFYK Sbjct: 241 GYPMGPFELLDYVGLDTTKFIVDGWHEMDAENPLHQPSPSLNKLVAENKFGKKTGEGFYK 300 Query: 313 YK 314 YK Sbjct: 301 YK 302 >3HDH-A nrPDB Length = 302 Score = 573 bits (1476), Expect = e-164, Method: Compositional matrix adjust. Identities = 274/292 (93%), Positives = 288/292 (98%) Query: 23 KKIIVKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKKF 82 KKI+VKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKKF Sbjct: 11 KKILVKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKKF 70 Query: 83 AENLKAGDEFVEKTLSTIATSTDAASVVHSTDLVVEAIVENLKVKNELFKRLDKFAAEHT 142 AEN KAGDEFVEKTLS+I+TSTDAASVVHSTDLVVEAIVENLKVK+ELFKRLDKFAAEHT Sbjct: 71 AENPKAGDEFVEKTLSSISTSTDAASVVHSTDLVVEAIVENLKVKSELFKRLDKFAAEHT 130 Query: 143 IFASNTSSLQITSIANATTRQDRFAGLHFFNPVPVMKLVEVIKTPMTSQKTFESLVDFSK 202 IFASNTSSLQITS+ANATTRQDRFAGLHFFNPVP+MKLVEV+KTPMTSQKT ESLVDFSK Sbjct: 131 IFASNTSSLQITSLANATTRQDRFAGLHFFNPVPLMKLVEVVKTPMTSQKTLESLVDFSK 190 Query: 203 ALGKHPVSCKDTPGFIVNRLLVPYLMEAIRLYERGDASKEDIDTAMKLGAGYPMGPFELL 262 LGKHPVSCKDTPGFIVNRLLVPYL+EA+RLYERGDASKEDIDTAMKLGAGYPMGPFELL Sbjct: 191 TLGKHPVSCKDTPGFIVNRLLVPYLIEAVRLYERGDASKEDIDTAMKLGAGYPMGPFELL 250 Query: 263 DYVGLDTTKFIVDGWHEMDAENPLHQPSPSLNKLVAENKFGKKTGEGFYKYK 314 DYVGLDTTKFI+DGWHEMD++NPL QPSP++NKLVAENKFGKKTGEGFYKYK Sbjct: 251 DYVGLDTTKFIIDGWHEMDSQNPLFQPSPAMNKLVAENKFGKKTGEGFYKYK 302 >4J0E-A nrPDB Length = 320 Score = 303 bits (775), Expect = 8e-83, Method: Compositional matrix adjust. Identities = 141/288 (48%), Positives = 201/288 (69%), Gaps = 1/288 (0%) Query: 27 VKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKKFAENL 86 +++V ++G G MG+GIAQV A++G V+L D + L ++ K I +S+ ++KK+ + Sbjct: 14 IRNVAIVGSGQMGSGIAQVTASSGFNVMLADVNKKALDRAMKAISQSVTHLSKKQKGTD- 72 Query: 87 KAGDEFVEKTLSTIATSTDAASVVHSTDLVVEAIVENLKVKNELFKRLDKFAAEHTIFAS 146 K +FV T+S I T + ++ V DL++EA +EN+ +K +F ++++ + +I + Sbjct: 73 KEKSDFVTLTMSRIKTCNNVSTAVADADLIIEAAIENIDLKRGIFAQIEQSCKKDSILTT 132 Query: 147 NTSSLQITSIANATTRQDRFAGLHFFNPVPVMKLVEVIKTPMTSQKTFESLVDFSKALGK 206 NTSS + +A + RF GLHFFNPVPVMKL+EVI++ TS +T+ +L+ F A+GK Sbjct: 133 NTSSFLLEDVAKGLQDKTRFGGLHFFNPVPVMKLLEVIRSDDTSDETYATLIKFGTAVGK 192 Query: 207 HPVSCKDTPGFIVNRLLVPYLMEAIRLYERGDASKEDIDTAMKLGAGYPMGPFELLDYVG 266 V+CKD+PGFIVNRLL+PY EA R+YERGDAS DID AMKLGAG+PMGPFEL DY+G Sbjct: 193 TTVACKDSPGFIVNRLLIPYFFEAARMYERGDASMTDIDEAMKLGAGHPMGPFELADYIG 252 Query: 267 LDTTKFIVDGWHEMDAENPLHQPSPSLNKLVAENKFGKKTGEGFYKYK 314 LDT KF++DGW E L + SP ++KLVAE K G+KTG+GFY YK Sbjct: 253 LDTVKFVMDGWAAKYPEVQLFEASPLVDKLVAEGKLGRKTGDGFYSYK 300 >4KUG-A nrPDB Length = 290 Score = 242 bits (618), Expect = 1e-64, Method: Compositional matrix adjust. Identities = 133/288 (46%), Positives = 180/288 (62%), Gaps = 9/288 (3%) Query: 27 VKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRK-VAKKKFAEN 85 +K V V+G G MGAGI Q AA G V++ D E+ + + I +SL K VAK+K E Sbjct: 1 MKKVFVLGAGTMGAGIVQAFAAKGCEVIVRDIKEEFVDRGIATITKSLSKLVAKEKITEA 60 Query: 86 LKAGDEFVEKTLSTIATSTDAASVVHSTDLVVEAIVENLKVKNELFKRLDKFAAEHTIFA 145 K E+ LS I+ +TD + DLVVEA +EN+K+K E+F LD TI A Sbjct: 61 DK------EEILSRISGTTDM-KLAADCDLVVEAAIENMKIKKEIFAELDGICKPETILA 113 Query: 146 SNTSSLQITSIANATTRQDRFAGLHFFNPVPVMKLVEVIKTPMTSQKTFESLVDFSKALG 205 SNTSSL IT +A+AT R D+ G+HFFNP PVMKLVEVI+ TSQ+TF+++ + S+++G Sbjct: 114 SNTSSLSITEVASATKRADKVIGMHFFNPAPVMKLVEVIRGAATSQETFDAVKEMSESIG 173 Query: 206 KHPVSCKDTPGFIVNRLLVPYLMEAIRLYERGDASKEDIDTAMKLGAGYPMGPFELLDYV 265 K PV + PGF+VNR+L+P + EA + + G A +EDID AMKLGA +PMGP L D + Sbjct: 174 KTPVEVAEAPGFVVNRILIPMINEATFILQEGVAKEEDIDAAMKLGANHPMGPLALGDLI 233 Query: 266 GLDTTKFIVDGWHEMDAENPLHQPSPSLNKLVAENKFGKKTGEGFYKY 313 GLD I+D + + ++ S L K V G+KTG+GFY Y Sbjct: 234 GLDVCLAIMDVLYNETGDTK-YRASSLLRKYVRAGWLGRKTGKGFYDY 280 >6ACQ-A nrPDB Length = 302 Score = 234 bits (597), Expect = 4e-62, Method: Compositional matrix adjust. Identities = 129/288 (44%), Positives = 179/288 (62%), Gaps = 9/288 (3%) Query: 27 VKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKK-KFAEN 85 +K V VIG G MG+GIAQ AA G VVL D ++ + + I ++L K+ KK K E Sbjct: 21 MKKVCVIGAGTMGSGIAQAFAAKGFEVVLRDIKDEFVDRGLDFINKNLSKLVKKGKIEEA 80 Query: 86 LKAGDEFVEKTLSTIATSTDAASVVHSTDLVVEAIVENLKVKNELFKRLDKFAAEHTIFA 145 K + L+ I+ + D ++ DLV+EA VE + +K ++F LD TI A Sbjct: 81 TKV------EILTRISGTVDL-NMAADCDLVIEAAVERMDIKKQIFADLDNICKPETILA 133 Query: 146 SNTSSLQITSIANATTRQDRFAGLHFFNPVPVMKLVEVIKTPMTSQKTFESLVDFSKALG 205 SNTSSL IT +A+AT R D+ G+HFFNP PVMKLVEVI+ TSQ+TF+++ + S A+G Sbjct: 134 SNTSSLSITEVASATKRPDKVIGMHFFNPAPVMKLVEVIRGIATSQETFDAVKETSIAIG 193 Query: 206 KHPVSCKDTPGFIVNRLLVPYLMEAIRLYERGDASKEDIDTAMKLGAGYPMGPFELLDYV 265 K PV + PGF+VNR+L+P + EA+ + G AS EDID AMKLGA +PMGP EL D++ Sbjct: 194 KDPVEVAEAPGFVVNRILIPMINEAVGILAEGIASVEDIDKAMKLGANHPMGPLELGDFI 253 Query: 266 GLDTTKFIVDGWHEMDAENPLHQPSPSLNKLVAENKFGKKTGEGFYKY 313 GLD I+D + ++ ++P L K V G+K+G+GFY Y Sbjct: 254 GLDICLAIMDVLYSETGDSK-YRPHTLLKKYVRAGWLGRKSGKGFYDY 300 >4PZE-A nrPDB Length = 284 Score = 221 bits (562), Expect = 4e-58, Method: Compositional matrix adjust. Identities = 117/287 (40%), Positives = 174/287 (60%), Gaps = 7/287 (2%) Query: 27 VKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKKFAENL 86 ++ V ++G G MG GIAQ A G VV+VD ++ + K + SL ++ KK E L Sbjct: 3 IRTVGIVGAGTMGNGIAQACAVVGLNVVMVDISDAAVQKGVATVASSLDRLIKK---EKL 59 Query: 87 KAGDEFVEKTLSTIATSTDAASVVHSTDLVVEAIVENLKVKNELFKRLDKFAAEHTIFAS 146 D+ L+ I ST + +TD+V+EA EN +K ++ K++D E+ I AS Sbjct: 60 TEADK--ASALARIKGSTSYDDL-KATDIVIEAATENYDLKVKILKQIDGIVGENVIIAS 116 Query: 147 NTSSLQITSIANATTRQDRFAGLHFFNPVPVMKLVEVIKTPMTSQKTFESLVDFSKALGK 206 NTSS+ IT +A T+R DRF G+HFFNPVPVM LVE+I+ TS T ++ SK LGK Sbjct: 117 NTSSISITKLAAVTSRADRFIGMHFFNPVPVMALVELIRGLQTSDTTHAAVEALSKQLGK 176 Query: 207 HPVSCKDTPGFIVNRLLVPYLMEAIRLYERGDASKEDIDTAMKLGAGYPMGPFELLDYVG 266 +P++ K++PGF+VNR+L P + EA + G AS E+ID MKLG +P+GP L D +G Sbjct: 177 YPITVKNSPGFVVNRILCPMINEAFCVLGEGLASPEEIDEGMKLGCNHPIGPLALADMIG 236 Query: 267 LDTTKFIVDGWHEMDAENPLHQPSPSLNKLVAENKFGKKTGEGFYKY 313 LDT +++ + + +P ++P+ + ++VA G+KTG G Y Y Sbjct: 237 LDTMLAVMEVLYT-EFADPKYRPAMLMREMVAAGYLGRKTGRGVYVY 282 >3MOG-A nrPDB Length = 483 Score = 211 bits (538), Expect = 3e-55, Method: Compositional matrix adjust. Identities = 122/294 (41%), Positives = 163/294 (55%), Gaps = 18/294 (6%) Query: 27 VKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLR-KVAKKKFAEN 85 V+ V VIG G MGAGIA+VAA+ GH V+L D + + L ++ GI L +V + K Sbjct: 5 VQTVAVIGSGTMGAGIAEVAASHGHQVLLYDISAEALTRAIDGIHARLNSRVTRGKLTA- 63 Query: 86 LKAGDEFVEKTLSTIATSTDAASVVHSTDLVVEAIVENLKVKNELFKRLDKFAAEHTIFA 145 E E+TL + TD ++ + DLV+EA E L+VK LF +L + T+ Sbjct: 64 -----ETCERTLKRLIPVTDIHALA-AADLVIEAASERLEVKKALFAQLAEVCPPQTLLT 117 Query: 146 SNTSSLQITSIANATTRQDRFAGLHFFNPVPVMKLVEVIKTPMTSQKTFESLVDFSKALG 205 +NTSS+ IT+IA +R AGLHFFNP PVMKLVEV+ T+ + E L + + + G Sbjct: 118 TNTSSISITAIAAEIKNPERVAGLHFFNPAPVMKLVEVVSGLATAAEVVEQLCELTLSWG 177 Query: 206 KHPVSCKDTPGFIVNRLLVPYLMEAIRLYERGDASKEDIDTAMKLGAGYPMGPFELLDYV 265 K PV C TPGFIVNR+ PY EA R E A+ E ID A++ GAG+PMGP EL D + Sbjct: 178 KQPVRCHSTPGFIVNRVARPYYSEAWRALEEQVAAPEVIDAALRDGAGFPMGPLELTDLI 237 Query: 266 GLD-----TTKFIVDGWHEMDAENPLHQPSPSLNKLVAENKFGKKTGEGFYKYK 314 G D T W E PS +LV + GKK+G G Y ++ Sbjct: 238 GQDVNFAVTCSVFNAFWQERR-----FLPSLVQQELVIGGRLGKKSGLGVYDWR 286 Score = 52.8 bits (125), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 23/55 (41%), Positives = 34/55 (61%) Query: 205 GKHPVSCKDTPGFIVNRLLVPYLMEAIRLYERGDASKEDIDTAMKLGAGYPMGPF 259 GK + D PG ++ R + + EA+ ++G AS++DIDTAM+LG YP GP Sbjct: 376 GKTVLQIADYPGMLIWRTVAMIINEALDALQKGVASEQDIDTAMRLGVNYPYGPL 430 >6HRD-A nrPDB Length = 317 Score = 210 bits (535), Expect = 6e-55, Method: Compositional matrix adjust. Identities = 119/290 (41%), Positives = 170/290 (58%), Gaps = 11/290 (3%) Query: 27 VKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESL-RKVAKKKFAEN 85 ++ V V+G G MG+GIA+V+A G V + + E ++ + I +SL R V+ K E Sbjct: 25 IQRVGVVGAGQMGSGIAEVSARAGVEVTVFEPAEALITAGRNRIVKSLERAVSAGKVTER 84 Query: 86 LKAGDEFVEKTLSTIATSTDAASVVHSTDLVVEAIVENLKVKNELFKRLDKFAAE-HTIF 144 + ++ L + +TD + LV+EA+VE+ VK+E+F LD+ + + Sbjct: 85 ER------DRALGLLTFTTDLNDL-SDRQLVIEAVVEDEAVKSEIFAELDRVVTDPDAVL 137 Query: 145 ASNTSSLQITSIANATTRQDRFAGLHFFNPVPVMKLVEVIKTPMTSQKTFESLVDF-SKA 203 ASNTSS+ I +A AT + R GLHFFNPVPV+ LVE+++T +T + +F S Sbjct: 138 ASNTSSIPIMKVAAATKQPQRVLGLHFFNPVPVLPLVELVRTLVTDEAAAARTEEFASTV 197 Query: 204 LGKHPVSCKDTPGFIVNRLLVPYLMEAIRLYERGDASKEDIDTAMKLGAGYPMGPFELLD 263 LGK V C D GF+VN LLVPYL+ AIR+ E G A+ ED+D A+ G +PMGP L D Sbjct: 198 LGKQVVRCSDRSGFVVNALLVPYLLSAIRMVEAGFATVEDVDKAVVAGLSHPMGPLRLSD 257 Query: 264 YVGLDTTKFIVDGWHEMDAENPLHQPSPSLNKLVAENKFGKKTGEGFYKY 313 VGLDT K I D E + + P + P P L ++V + GKK+G GFY Y Sbjct: 258 LVGLDTLKLIADKMFE-EFKEPHYGPPPLLLRMVEAGQLGKKSGRGFYTY 306 >2WTB-A nrPDB Length = 725 Score = 162 bits (409), Expect = 2e-40, Method: Compositional matrix adjust. Identities = 105/301 (34%), Positives = 158/301 (52%), Gaps = 38/301 (12%) Query: 27 VKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDIL----AKSKKGIEESLRK--VAKK 80 +K V +IGGGLMG+GIA + + V+L + E L + K ++ +RK ++++ Sbjct: 312 IKKVAIIGGGLMGSGIATALILSNYPVILKEVNEKFLEAGIGRVKANLQSRVRKGSMSQE 371 Query: 81 KFAENLKAGDEFVEKTLSTIATSTDAASVVHSTDLVVEAIVENLKVKNELFKRLDKFAAE 140 KF EKT+S + S D S D+V+EA++EN+ +K ++F L+K+ + Sbjct: 372 KF-----------EKTMSLLKGSLDYESF-RDVDMVIEAVIENISLKQQIFADLEKYCPQ 419 Query: 141 HTIFASNTSSLQITSIANATTRQDRFAGLHFFNPVPVMKLVEVIKTPMTSQKTFESLVDF 200 H I ASNTS++ + I T QDR G HFF+P +M L+E+++T TS + L+D Sbjct: 420 HCILASNTSTIDLNKIGERTKSQDRIVGAHFFSPAHIMPLLEIVRTNHTSAQVIVDLLDV 479 Query: 201 SKALGKHPVSCKDTPGFIVNRLLVPYLMEAIRLYERGDASKEDIDTAMKLGAGYPMGPFE 260 K + K PV + GF VNR+ PY A+ L E G A ID A+ G PMGPF Sbjct: 480 GKKIKKTPVVVGNCTGFAVNRMFFPYTQAAMFLVECG-ADPYLIDRAIS-KFGMPMGPFR 537 Query: 261 LLDYVGLDT-----TKFIVDGWHEMDAEN---PLHQPSPSLNKLVAENKFGKKTGEGFYK 312 L D VG T+FI + + E ++ PL Q + + G+ T +GFY Sbjct: 538 LCDLVGFGVAIATATQFI-ENFSERTYKSMIIPLMQ---------EDKRAGEATRKGFYL 587 Query: 313 Y 313 Y Sbjct: 588 Y 588 >4DYD-A nrPDB Length = 283 Score = 160 bits (404), Expect = 9e-40, Method: Compositional matrix adjust. Identities = 106/290 (36%), Positives = 153/290 (52%), Gaps = 13/290 (4%) Query: 27 VKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKKFAENL 86 + +VTV+G G++G+ IA A G V D D L +KK E L V +K+ A Sbjct: 4 ITNVTVLGTGVLGSQIAFQTAFHGFAVTAYDINTDALDAAKKRFE-GLAAVYEKEVA--- 59 Query: 87 KAGDEFVEKTLSTIATSTDAASVVHSTDLVVEAIVENLKVKNELFKRLDKFAAEHTIFAS 146 A D +K L I S D A V DLV+EA+ E+L +K +++ +L + A TIFA+ Sbjct: 60 GAADGAAQKALGGIRYSDDLAQAVKDADLVIEAVPESLDLKRDIYTKLGELAPAKTIFAT 119 Query: 147 NTSSLQITSIANATTRQDRFAGLHFFNPVPVMKLVEVIKTPMTSQKTFESLVDFSKALGK 206 N+S+L + + T R D+F LHF N V V EV+ T T + ++ +V+F+ A+G Sbjct: 120 NSSTLLPSDLVGYTGRGDKFLALHFANHVWVNNTAEVMGTTKTDPEVYQQVVEFASAIGM 179 Query: 207 HPVSC-KDTPGFIVNRLLVPYLMEAIRLYERGDASKEDIDTAMKLGAGYPMGPFELLDYV 265 P+ K+ G+++N LLVP L A L G A E ID ++G G P GPFE+ D V Sbjct: 180 VPIELKKEKAGYVLNSLLVPLLDAAAELLVDGIADPETIDKTWRIGTGAPKGPFEIFDIV 239 Query: 266 GLDTTKFI--VDGWHEMDAENPLHQPSPSLNKLVAENKFGKKTGEGFYKY 313 GL T I V G + + L + + + K G TGEGFY+Y Sbjct: 240 GLTTAYNISSVSGPKQREFAAYLKE------NYIDKGKLGLATGEGFYRY 283 >5ZRV-A nrPDB Length = 763 Score = 159 bits (403), Expect = 1e-39, Method: Compositional matrix adjust. Identities = 98/289 (33%), Positives = 155/289 (53%), Gaps = 10/289 (3%) Query: 27 VKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKKFAENL 86 VKH+ ++G GLMGAGIAQV+ G +L D T L + ++ + + L KKK + Sbjct: 361 VKHLAILGAGLMGAGIAQVSVDKGLKTILKDATLTALDRGQQQVFKGLNDKVKKKALTSF 420 Query: 87 KAGDEFVEKTLSTIATSTDAASVVHSTDLVVEAIVENLKVKNELFKRLDKFAAEHTIFAS 146 + F S + D D+V+EA+ E+L +K+ + K ++ +H IFAS Sbjct: 421 ERDSIF-----SNLTGQLDYQGF-EKADMVIEAVFEDLSLKHRVLKEVEAVIPDHCIFAS 474 Query: 147 NTSSLQITSIANATTRQDRFAGLHFFNPVPVMKLVEVIKTPMTSQKTFESLVDFSKALGK 206 NTS+L I+ IA + R ++ G+H+F+PV M+L+E+I T TS+ T S V GK Sbjct: 475 NTSALPISEIAAVSKRPEKVIGMHYFSPVDKMQLLEIITTEKTSKDTSASAVAVGLKQGK 534 Query: 207 HPVSCKDTPGFIVNRLLVPYLMEAIRLYERG-DASKEDIDTAMKLGAGYPMGPFELLDYV 265 + KD PGF R L P + E IR+ + G D K D ++ G+P+G L+D V Sbjct: 535 VIIVVKDGPGFYTTRCLAPMMSEVIRILQEGVDPKKLD---SLTTSFGFPVGAATLVDEV 591 Query: 266 GLDTTKFIVDGWHEMDAENPLHQPSPSLNKLVAENKFGKKTGEGFYKYK 314 G+D K + + ++ E L ++V++ G+K+G+GFY Y+ Sbjct: 592 GVDVAKHVAEDLGKVFGERFGGGNPELLTQMVSKGFLGRKSGKGFYIYQ 640 >4B3J-A nrPDB Length = 736 Score = 157 bits (396), Expect = 7e-39, Method: Compositional matrix adjust. Identities = 101/311 (32%), Positives = 165/311 (53%), Gaps = 16/311 (5%) Query: 9 MRSVSSSSTASASAKKIIVKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKK 68 ++++++ + K +K + V+G G+MGAGIA V+A G+ VVL D + + AK K Sbjct: 323 LQAINAGGSRPEGIGKTPIKRIGVLGAGMMGAGIAYVSAKAGYEVVLKDVSLEAAAKGK- 381 Query: 69 GIEESLRKVAKKKFAENLKAGDEFVEKTLSTIATSTDAASVVHSTDLVVEAIVENLKVKN 128 G E L + K E + E + L+ I + DAA D V+EA+ EN ++K+ Sbjct: 382 GYSEKL----EAKALERGRTTQERSDALLARITPTADAADF-KGVDFVIEAVFENQELKH 436 Query: 129 ELFKRLDKFAAEHTIFASNTSSLQITSIANATTRQDRFAGLHFFNPVPVMKLVEVIKTPM 188 ++F ++ + I SNTS+L IT +A RQ+ F G+HFF+PV M LVE+IK Sbjct: 437 KVFGEIEDIVEPNAILGSNTSTLPITGLATGVKRQEDFIGIHFFSPVDKMPLVEIIKGEK 496 Query: 189 TSQKTFESLVDFSKALGKHPVSCKDTPGFIVNRLLVPYLMEAIRLYERG--DASKEDIDT 246 TS + + D++ A+GK P+ D+ GF +R++ ++ EA+ + G AS E + Sbjct: 497 TSDEALARVFDYTLAIGKTPIVVNDSRGFFTSRVIGTFVNEALAMLGEGVEPASIEQAGS 556 Query: 247 AMKLGAGYPMGPFELLDYVGLDTT-KFIVDGWHEMDAENPLHQPSPS---LNKLVAENKF 302 AGYP P +L D + L+ K V ++ +QP P+ + K++ + Sbjct: 557 Q----AGYPAPPLQLSDELNLELMHKIAVATRKGVEDAGGTYQPHPAEAVVEKMIELGRS 612 Query: 303 GKKTGEGFYKY 313 G+ G GFY+Y Sbjct: 613 GRLKGAGFYEY 623 >4OM8-A nrPDB Length = 309 Score = 146 bits (368), Expect = 1e-35, Method: Compositional matrix adjust. Identities = 92/292 (31%), Positives = 150/292 (51%), Gaps = 14/292 (4%) Query: 26 IVKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKKFAEN 85 +++++ +IG G MG G+A A G VV D + +++ S+ VA+ Sbjct: 1 MIRNIAIIGLGTMGPGMAARLARGGLQVVAYDVAPAAIERAR-----SMLSVAETVLD-- 53 Query: 86 LKAGDEFVEKTLSTIATSTDAASVVHSTDLVVEAIVENLKVKNELFKRLDKFAAEHTIFA 145 G + T+ + D V DLV+E + EN+ +K ++++ +D + TI A Sbjct: 54 -ALGIALPSAGVGTVRFTDDIGDAVSGADLVIENVPENISIKADVYRTIDGLIGQDTIVA 112 Query: 146 SNTSSLQITSIANATTRQDRFAGLHFFNPVPVMKLVEVIKTPMTSQKTFESLVDFSKALG 205 S+TS + IT + + +R G+H+ NP ++ ++EVI T+ +T ++ D +++G Sbjct: 113 SDTSGIPITKLQAHISYPERMVGMHWSNPPHIIPMIEVIAGEKTAPQTVATIRDLIRSIG 172 Query: 206 KHPVSC-KDTPGFIVNRLLVPYLMEAIRLYERGDASKEDIDTAMKLGAGYP---MGPFEL 261 PV KD PGF+ NR+L L EA+ L ERG ED+DT + G GY +GP L Sbjct: 173 LLPVVVKKDVPGFVENRVLYALLREAVDLVERGVIDPEDLDTCVSWGIGYKIAVIGPMAL 232 Query: 262 LDYVGLDTTKFIVDGWHEMDAENPLHQPSPSLNKLVAENKFGKKTGEGFYKY 313 LD GLD K V + D N +P + + + +KFG K+GEG + Y Sbjct: 233 LDMAGLDIYKS-VSSFLNADLSN-RDDVAPMVLEKTSASKFGIKSGEGMFCY 282 >3ZWA-A nrPDB Length = 742 Score = 143 bits (361), Expect = 9e-35, Method: Compositional matrix adjust. Identities = 104/310 (33%), Positives = 152/310 (49%), Gaps = 21/310 (6%) Query: 13 SSSSTASASAKKIIVKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEE 72 S +S +ASA+ V V V+G G MG GIA A G +VV V+ L +KK I Sbjct: 304 SGASWKTASAQP--VSSVGVLGLGTMGRGIAISFARVGISVVAVESDPKQLDAAKKIITF 361 Query: 73 SLRKVAKKKFAENLKAGDEFVEKTLSTIATSTDAASVVHSTDLVVEAIVENLKVKNELFK 132 +L K A + + + + ST ST DLVVEA+ E++ +K ++F Sbjct: 362 TLEKEASRAHQNGQASAKPKLRFSSSTKELST--------VDLVVEAVFEDMNLKKKVFA 413 Query: 133 RLDKFAAEHTIFASNTSSLQITSIANATTRQDRFAGLHFFNPVPVMKLVEVIKTPMTSQK 192 L +NTS+L + IA++T R G HFF+P VM+L+EVI + +S Sbjct: 414 ELSALCKPGAFLCTNTSALNVDDIASSTDRPQLVIGTHFFSPAHVMRLLEVIPSRYSSPT 473 Query: 193 TFESLVDFSKALGKHPVSCKDTPGFIVNRLLVPYLMEAIRLYERGDASKEDIDTAMKLGA 252 T +++ SK +GK V + GF+ NR+L PY + L E G + ED+D ++ Sbjct: 474 TIATVMSLSKKIGKIGVVVGNCYGFVGNRMLAPYYNQGFFLLEEG-SKPEDVDGVLE-EF 531 Query: 253 GYPMGPFELLDYVGLDTTKFIVDGWHEMDAENPLHQP---------SPSLNKLVAENKFG 303 G+ MGPF + D GLD I G P P SP + L +FG Sbjct: 532 GFKMGPFRVSDLAGLDVGWKIRKGQGLTGPSLPPGTPVRKRGNSRYSPLGDMLCEAGRFG 591 Query: 304 KKTGEGFYKY 313 +KTG+G+Y+Y Sbjct: 592 QKTGKGWYQY 601 Score = 39.7 bits (91), Expect = 0.002, Method: Compositional matrix adjust. Identities = 28/87 (32%), Positives = 42/87 (48%), Gaps = 4/87 (4%) Query: 218 IVNRLLVPYLMEAIRLYERGDASK-EDIDTAMKLGAGYPM---GPFELLDYVGLDTTKFI 273 I+ R L + EA R+ E G A++ E ID G G+P GP VGL T Sbjct: 638 ILERCLYSLINEAFRILEEGMAARPEHIDVIYLHGYGWPRHKGGPMFYAASVGLPTVLEK 697 Query: 274 VDGWHEMDAENPLHQPSPSLNKLVAEN 300 + ++ + + P +PS L +LVA+ Sbjct: 698 LQKYYRQNPDIPQLEPSDYLRRLVAQG 724 >1ZCJ-A nrPDB Length = 463 Score = 143 bits (360), Expect = 1e-34, Method: Compositional matrix adjust. Identities = 107/310 (34%), Positives = 156/310 (50%), Gaps = 21/310 (6%) Query: 13 SSSSTASASAKKIIVKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEE 72 S +S +ASA+ V V V+G G MG GIA A G +VV V+ L +KK I Sbjct: 25 SGASWKTASAQP--VSSVGVLGLGTMGRGIAISFARVGISVVAVESDPKQLDAAKKIITF 82 Query: 73 SLRKVAKKKFAENLKAGDEFVEKTLSTIATSTDAASVVHSTDLVVEAIVENLKVKNELFK 132 +L K A + +N +A K ++ST S V DLVVEA+ E++ +K ++F Sbjct: 83 TLEKEASRAH-QNGQAS----AKPKLRFSSSTKELSTV---DLVVEAVFEDMNLKKKVFA 134 Query: 133 RLDKFAAEHTIFASNTSSLQITSIANATTRQDRFAGLHFFNPVPVMKLVEVIKTPMTSQK 192 L +NTS+L + IA++T R G HFF+P VM+L+EVI + +S Sbjct: 135 ELSALCKPGAFLCTNTSALNVDDIASSTDRPQLVIGTHFFSPAHVMRLLEVIPSRYSSPT 194 Query: 193 TFESLVDFSKALGKHPVSCKDTPGFIVNRLLVPYLMEAIRLYERGDASKEDIDTAMKLGA 252 T +++ SK +GK V + GF+ NR+L PY + L E G + ED+D ++ Sbjct: 195 TIATVMSLSKKIGKIGVVVGNCYGFVGNRMLAPYYNQGFFLLEEG-SKPEDVDGVLE-EF 252 Query: 253 GYPMGPFELLDYVGLDTTKFIVDGWHEMDAENPLHQP---------SPSLNKLVAENKFG 303 G+ MGPF + D GLD I G P P SP + L +FG Sbjct: 253 GFKMGPFRVSDLAGLDVGWKIRKGQGLTGPSLPPGTPVRKRGNSRYSPLGDMLCEAGRFG 312 Query: 304 KKTGEGFYKY 313 +KTG+G+Y+Y Sbjct: 313 QKTGKGWYQY 322 Score = 39.7 bits (91), Expect = 0.002, Method: Compositional matrix adjust. Identities = 28/87 (32%), Positives = 42/87 (48%), Gaps = 4/87 (4%) Query: 218 IVNRLLVPYLMEAIRLYERGDASK-EDIDTAMKLGAGYPM---GPFELLDYVGLDTTKFI 273 I+ R L + EA R+ E G A++ E ID G G+P GP VGL T Sbjct: 359 ILERCLYSLINEAFRILEEGMAARPEHIDVIYLHGYGWPRHKGGPMFYAASVGLPTVLEK 418 Query: 274 VDGWHEMDAENPLHQPSPSLNKLVAEN 300 + ++ + + P +PS L +LVA+ Sbjct: 419 LQKYYRQNPDIPQLEPSDYLRRLVAQG 445 >2D3T-A nrPDB Length = 715 Score = 142 bits (359), Expect = 1e-34, Method: Compositional matrix adjust. Identities = 80/204 (39%), Positives = 116/204 (56%), Gaps = 4/204 (1%) Query: 112 STDLVVEAIVENLKVKNELFKRLDKFAAEHTIFASNTSSLQITSIANATTRQDRFAGLHF 171 + DLVVEA+VEN KVK + ++ E I ASNTS++ I+ +A A R + F G+HF Sbjct: 393 NVDLVVEAVVENPKVKQAVLAEVENHVREDAILASNTSTISISLLAKALKRPENFVGMHF 452 Query: 172 FNPVPVMKLVEVIKTPMTSQKTFESLVDFSKALGKHPVSCKDTPGFIVNRLLVPYLMEAI 231 FNPV +M LVEVI+ +S + V ++K +GK+P+ D PGF+VNR+L PY Sbjct: 453 FNPVHMMPLVEVIRGEKSSDLAVATTVAYAKKMGKNPIVVNDCPGFLVNRVLFPYFGGFA 512 Query: 232 RLYERG-DASKEDIDTAMKLGAGYPMGPFELLDYVGLDTTKFIVDGWHEMDAENPLHQPS 290 +L G D + ID M+ G+PMGP L+D VG+DT D E + Sbjct: 513 KLVSAGVDFVR--IDKVME-KFGWPMGPAYLMDVVGIDTGHHGRDVMAEGFPDRMKDDRR 569 Query: 291 PSLNKLVAENKFGKKTGEGFYKYK 314 +++ L + G+K G+GFY Y+ Sbjct: 570 SAIDALYEAKRLGQKNGKGFYAYE 593 Score = 37.7 bits (86), Expect = 0.006, Method: Compositional matrix adjust. Identities = 23/98 (23%), Positives = 46/98 (46%), Gaps = 14/98 (14%) Query: 218 IVNRLLVPYLMEAIRLYERGDA-SKEDIDTAMKLGAGYPM---GPFELLDYVGLDTTKFI 273 I+N +++P +E +R E G + + D + G G+P+ G +D +G+ + Sbjct: 627 IINWMMIPLCLETVRCLEDGIVETAAEADMGLVYGIGFPLFRGGALRYIDSIGVAEFVAL 686 Query: 274 VDGWHEMDAENPLHQPSPSLNKLVAENKFGKKTGEGFY 311 D + E+ A L+ P+ L ++ K G+ F+ Sbjct: 687 ADQYAELGA---LYHPTAKLREMA-------KNGQSFF 714 >6IUM-B nrPDB Length = 701 Score = 141 bits (355), Expect = 5e-34, Method: Compositional matrix adjust. Identities = 96/291 (32%), Positives = 149/291 (51%), Gaps = 17/291 (5%) Query: 27 VKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKKFAENL 86 ++ V VIG G MG GI+ G V +++ ++ L + I ++ AKK Sbjct: 292 IEKVAVIGAGTMGGGISMNFLNAGIPVTILETKQEALDRGVGIIRKNYENSAKKG----- 346 Query: 87 KAGDEFVEKTLSTIATSTDAASVVHSTDLVVEAIVENLKVKNELFKRLDKFAAEHTIFAS 146 K E VE+ + ++T T + + DL++EA+ E + VK +FK+LD+ A + I AS Sbjct: 347 KLTQEKVEQRMGLLST-TLSYDDLKDADLIIEAVFEEMGVKETVFKKLDEVAKQGAILAS 405 Query: 147 NTSSLQITSIANATTRQDRFAGLHFFNPVPVMKLVEVIKTPMTSQKTFESLVDFSKALGK 206 NTS+L + IA+ T R G+HFF+P VMKL+EV++ T + +++ K + K Sbjct: 406 NTSTLDVNKIASFTKRPQDVVGMHFFSPANVMKLLEVVRGEKTGKDVLATVMQVGKKIKK 465 Query: 207 HPVSCKDTPGFIVNRLLVPYLMEAIRLYERGDASKEDIDTAMKLGAGYPMGPFELLDYVG 266 V GFI NR++ Y +A L + G A E +D A++ G+ MGPF + D G Sbjct: 466 TAVVSGVCDGFIGNRMIEQYSRQAGYLLDEG-ALPEQVDKAIEK-FGFAMGPFRMGDLAG 523 Query: 267 LDTTKFIVDGW---HEMDAENPLHQPSPSLNKLVAENKFGKKTGEGFYKYK 314 D GW + P Q S + + L +FG+KTG G+Y YK Sbjct: 524 NDI------GWAIRKRRAVDKPEIQYSKTADLLCEMGRFGQKTGAGWYDYK 568 Score = 44.7 bits (104), Expect = 6e-05, Method: Compositional matrix adjust. Identities = 41/127 (32%), Positives = 58/127 (45%), Gaps = 19/127 (14%) Query: 185 KTPMTSQKTFESLVDFSKALG--KHPVSCKDTPGFIVNRLLVPYLMEAIRLYERGDASK- 241 + P +Q+ + +V SK LG + +S ++ IV RL+ + E R+ E G ASK Sbjct: 572 RKPYPNQQVNDMIVQHSKDLGITRRKISDEE----IVERLVFALVNEGARILEEGIASKA 627 Query: 242 EDIDTAMKLGAGYPM---GPFELLDYVGLD----TTKFIVDGWHEMDAENPLHQPSPSLN 294 DID G G+P+ GP D VGL + K G+H Q +P L Sbjct: 628 SDIDMVYLTGYGFPLFRGGPMLYADQVGLYNVALSMKRYAKGYH-----GEAWQVAPLLQ 682 Query: 295 KLVAENK 301 KL E K Sbjct: 683 KLADEGK 689 >3K6J-A nrPDB Length = 460 Score = 129 bits (325), Expect = 1e-30, Method: Compositional matrix adjust. Identities = 88/288 (30%), Positives = 146/288 (50%), Gaps = 20/288 (6%) Query: 27 VKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKKFAENL 86 V V +IGGG MG +A G LV + E + K+ +E + +K F Sbjct: 54 VNSVAIIGGGTMGKAMAICFGLAGIETFLVVRNEQ---RCKQELE--VMYAREKSFK--- 105 Query: 87 KAGDEFVEKTLSTIATSTDAASVVHSTDLVVEAIVENLKVKNELFKRLDKFAAEHTIFAS 146 + D+ +EK + + ++D + + DL+VE+++E++K+K ELF L+ IF + Sbjct: 106 RLNDKRIEKINANLKITSDFHKL-SNCDLIVESVIEDMKLKKELFANLENICKSTCIFGT 164 Query: 147 NTSSLQITSIANATTRQDRFAGLHFFNPVPVMKLVEVIKTPMTSQKTFESLVDFSKALGK 206 NTSSL + I++ G+HFFNP V++LVE+I TS + + +++ K Sbjct: 165 NTSSLDLNEISSVLRDPSNLVGIHFFNPANVIRLVEIIYGSHTSSQAIATAFQACESIKK 224 Query: 207 HPVSCKDTPGFIVNRLLVPYLMEAIRL-YERGDASKEDIDTAMKLGAGYPMGPFELLDYV 265 PV + F+ NRLL Y ++ +L YE G + ID + G+ MGP + D Sbjct: 225 LPVLVGNCKSFVFNRLLHVYFDQSQKLMYEYGYLPHQ-IDKIIT-NFGFLMGPMTVADMN 282 Query: 266 GLDTTKFIVDGWHEMDAENPLHQPSPSLNKLVAENKFGKKTGEGFYKY 313 G D + ++ EN L +P+P ++ ++G+KT +GFYKY Sbjct: 283 GFDVME-------KLKKENGL-EPNPIEKEMWRLKRYGRKTNKGFYKY 322 Score = 34.3 bits (77), Expect = 0.074, Method: Compositional matrix adjust. Identities = 21/68 (30%), Positives = 31/68 (45%), Gaps = 4/68 (5%) Query: 218 IVNRLLVPYLMEAIRLYERGDASKED-IDTAMKLGAGYPM---GPFELLDYVGLDTTKFI 273 ++N +L P + E R E G S E ID LG G+P+ GP GLD + Sbjct: 358 VINFMLYPTVNEGYRCIEEGVISNESLIDIMFILGFGWPIHSGGPMRFGKTEGLDKIANM 417 Query: 274 VDGWHEMD 281 + W ++ Sbjct: 418 LVHWSSLE 425 >1ZEJ-A nrPDB Length = 293 Score = 123 bits (308), Expect = 1e-28, Method: Compositional matrix adjust. Identities = 94/287 (32%), Positives = 139/287 (48%), Gaps = 33/287 (11%) Query: 30 VTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKKFAENLKAG 89 V VIG GLMG GIA +A A+ H VVL D +E L +++ I E L ++K +F L+ Sbjct: 15 VFVIGAGLMGRGIA-IAIASKHEVVLQDVSEKALEAAREQIPEEL--LSKIEFTTTLEK- 70 Query: 90 DEFVEKTLSTIATSTDAASVVHSTDLVVEAIVENLKVKNELFKRLDKFAAEHTIFASNTS 149 V D+V+EA+ E+L K E+ + +++ + SNTS Sbjct: 71 --------------------VKDCDIVMEAVFEDLNTKVEVLREVERLT--NAPLCSNTS 108 Query: 150 SLQITSIANATTRQDRFAGLHFFNPVPVMKLVEVIKTPMTSQKTFESLVDFSKALGKHPV 209 + + IA RF G+H+ NP VM LVE++ + T KT + F + LGK V Sbjct: 109 VISVDDIAERLDSPSRFLGVHWMNPPHVMPLVEIVISRFTDSKTVAFVEGFLRELGKEVV 168 Query: 210 SCKDTPGFIVNRLLVPYLMEAIRLYERGDASKEDIDTAMK--LGAGYPM-GPFELLDYVG 266 CK +VNR L EA R+ E G ED+D K LG Y + GP LDY+G Sbjct: 169 VCKGQS--LVNRFNAAVLSEASRMIEEG-VRAEDVDRVWKHHLGLLYTLFGPLGNLDYIG 225 Query: 267 LDTTKFIVDGWHEMDAENPLHQPSPSLNKLVAENKFGKKTGEGFYKY 313 LD + ++ + +P L + + + + G K G+G Y+Y Sbjct: 226 LDVAYYASLYLYKRFGDEKF-KPPEWLQEKIKKGEVGVKAGKGIYEY 271 >3F3S-A nrPDB Length = 313 Score = 90.1 bits (222), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 66/235 (28%), Positives = 113/235 (48%), Gaps = 8/235 (3%) Query: 30 VTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKKFAENLKAG 89 V ++G G++G A + A+ G V L D + + + + I + ++ + + A +LK G Sbjct: 6 VVIVGSGVIGRSWAMLFASGGFQVKLYDIEQQQIRNALENIRKEMKLLEQ---AGSLK-G 61 Query: 90 DEFVEKTLSTIATSTDAASVVHSTDLVVEAIVENLKVKNELFKRLDKFAAEHTIFASNTS 149 VE+ LS I+ + V + E + E+L++K ++F +LD + I +S+TS Sbjct: 62 SLSVEEQLSLISGCPNIQEAVEGAMHIQECVPEDLELKKKIFAQLDSIIDDRVILSSSTS 121 Query: 150 SLQITSIANATTRQDRFAGLHFFNPVPVMKLVEVIKTPMTSQKTFESLVDFSKALGKHPV 209 L + + + H NP + LVE++ P T+ T + K +G+ P+ Sbjct: 122 CLMPSKLFAGLVHVKQCIVAHPVNPPYYIPLVELVPHPETAPTTVDRTHALMKKIGQCPM 181 Query: 210 SC-KDTPGFIVNRLLVPYLMEAIRLYERGDASKEDIDTAMKLGAGYP---MGPFE 260 K+ GF++NRL + EA RL E G S D+D M G G +GP E Sbjct: 182 RVQKEVAGFVLNRLQYAIISEAWRLVEEGIVSPSDLDLVMSEGLGMRYAFIGPLE 236 >3ADO-A nrPDB Length = 319 Score = 86.7 bits (213), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 70/237 (29%), Positives = 110/237 (46%), Gaps = 8/237 (3%) Query: 30 VTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKKFAENLKAG 89 V ++G GL+G A + A+ G V L D I + G E++RK K G Sbjct: 9 VLIVGSGLVGRSWAMLFASGGFRVKLYD----IEPRQITGALENIRKEMKSLQQSGSLKG 64 Query: 90 DEFVEKTLSTIATSTDAASVVHSTDLVVEAIVENLKVKNELFKRLDKFAAEHTIFASNTS 149 E+ LS I++ T+ A V + E + ENL +K ++F +LD + + +S++S Sbjct: 65 SLSAEEQLSLISSCTNLAEAVEGVVHIQECVPENLDLKRKIFAQLDSIVDDRVVLSSSSS 124 Query: 150 SLQITSIANATTRQDRFAGLHFFNPVPVMKLVEVIKTPMTSQKTFESLVDFSKALGKHPV 209 L + + + H NP + LVE++ P TS T + + +G+ PV Sbjct: 125 CLLPSKLFTGLAHVKQCIVAHPVNPPYYIPLVELVPHPETSPATVDRTHALMRKIGQSPV 184 Query: 210 SC-KDTPGFIVNRLLVPYLMEAIRLYERGDASKEDIDTAMKLGAGYP---MGPFELL 262 K+ GF++NRL + EA RL E G S D+D M G G +GP E + Sbjct: 185 RVLKEIDGFVLNRLQYAIISEAWRLVEEGIVSPSDLDLVMSDGLGMRYAFIGPLETM 241 >3CTV-A nrPDB Length = 110 Score = 45.8 bits (107), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 21/40 (52%), Positives = 27/40 (67%) Query: 229 EAIRLYERGDASKEDIDTAMKLGAGYPMGPFELLDYVGLD 268 EA++L E G A+ +DIDTA+KLG P GPFEL G + Sbjct: 30 EAVKLVEMGVATPQDIDTAIKLGLNRPFGPFELAKQFGAE 69 >5ER0-A nrPDB Length = 518 Score = 37.4 bits (85), Expect = 0.008, Method: Compositional matrix adjust. Identities = 16/38 (42%), Positives = 24/38 (63%) Query: 28 KHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAK 65 K +TVIG G +GA +A+ + TGH V L+D ++ K Sbjct: 198 KRITVIGAGYIGAELAEAYSTTGHDVTLIDAMARVMPK 235 >2CDU-A nrPDB Length = 452 Score = 34.3 bits (77), Expect = 0.067, Method: Compositional matrix adjust. Identities = 43/167 (25%), Positives = 72/167 (43%), Gaps = 25/167 (14%) Query: 28 KHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTE------------DILAKSKKGIEESLR 75 K +T+IG G +GA +A+ + + V L+D E DILAK + + Sbjct: 150 KTITIIGSGYIGAELAEAYSNQNYNVNLIDGHERVLYKYFDKEFTDILAKDYEA--HGVN 207 Query: 76 KVAKKKFAENLKAGDEFVEKTLSTIATSTDAASVV----HSTDLVVE--AIVENLKVKNE 129 V K A + DE + KTL +D A + +T+L+ A+++N + + Sbjct: 208 LVLGSKVAAFEEVDDEIITKTLDGKEIKSDIAILCIGFRPNTELLKGKVAMLDNGAIITD 267 Query: 130 LF---KRLDKFAAEHT--IFASNTSSLQITSIANATTRQDRFAGLHF 171 + D FAA + + + T+S +A RQ R GL+ Sbjct: 268 EYMHSSNRDIFAAGDSAAVHYNPTNSNAYIPLATNAVRQGRLVGLNL 314 >3KVE-A nrPDB Length = 486 Score = 33.5 bits (75), Expect = 0.11, Method: Compositional matrix adjust. Identities = 14/33 (42%), Positives = 20/33 (60%) Query: 28 KHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTE 60 KHV V+G G+ G A V A GH V +++ +E Sbjct: 34 KHVVVVGAGMSGLSAAYVLAGAGHKVTVLEASE 66 >1F8S-A nrPDB Length = 498 Score = 33.5 bits (75), Expect = 0.13, Method: Compositional matrix adjust. Identities = 13/33 (39%), Positives = 20/33 (60%) Query: 28 KHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTE 60 KHV ++G G+ G A V A GH V +++ +E Sbjct: 34 KHVVIVGAGMAGLSAAYVLAGAGHQVTVLEASE 66 >2BC1-A nrPDB Length = 490 Score = 33.5 bits (75), Expect = 0.14, Method: Compositional matrix adjust. Identities = 30/103 (29%), Positives = 49/103 (47%), Gaps = 14/103 (13%) Query: 7 QFMRSVSSSSTASASAKKIIVKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKS 66 QF++ +S+ A + +K V V+G G +G +A+ G VVL+D + LA Sbjct: 174 QFVKLYQNSADVIAKLENKDIKRVAVVGAGYIGVELAEAFQRKGKEVVLIDVVDTCLAGY 233 Query: 67 ---------KKGIEESLRKVAKKKFAENLK--AGDEFVEKTLS 98 K +EE ++A F E +K AG+ VEK ++ Sbjct: 234 YDRDLTDLMAKNMEEHGIQLA---FGETVKEVAGNGKVEKIIT 273 >4MO2-B nrPDB Length = 368 Score = 32.7 bits (73), Expect = 0.21, Method: Compositional matrix adjust. Identities = 44/215 (20%), Positives = 78/215 (36%), Gaps = 60/215 (27%) Query: 32 VIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKKFAENLKAGDE 91 ++G GL G+ A A G+T ++V+Q E I + EN+K Sbjct: 6 IVGSGLFGSIFAYEATEKGYTCLVVEQREHIGGNC---------------YTENIK---- 46 Query: 92 FVEKTLSTIATSTDAASVVHSTDLVVEAIVENLKVKNELFKRLDKFAAEHTIFASNTSSL 151 I A + ++D ++ +++F E F ++ ++ Sbjct: 47 -------NINVHKYGAHIFRTSD-------------QNIWDYMNQF-CEFNHFINSPIAI 85 Query: 152 QITSIANATTRQDRFAGLHFF-NPVPVMKLVE----VIKTP----------MTSQKTFES 196 I N + F+ L P K++E +I+ P + +E Sbjct: 86 YKDEIYNLPFNMNTFSKLWGIKTPNEARKIIEMQKQIIQHPPKNLEEQAISLVGTDVYEK 145 Query: 197 LVD--FSKALGKHPVSCKDTPGFIVNRLLVPYLME 229 L+ K G+ SCKD P I+ RL V Y+ + Sbjct: 146 LIKGYTEKQWGR---SCKDLPASIIRRLPVRYIYD 177 >1REO-A nrPDB Length = 486 Score = 32.3 bits (72), Expect = 0.24, Method: Compositional matrix adjust. Identities = 13/33 (39%), Positives = 20/33 (60%) Query: 28 KHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTE 60 KHV V+G G+ G A V + GH V +++ +E Sbjct: 34 KHVVVVGAGMSGLSAAYVLSGAGHQVTVLEASE 66 >3KYB-A nrPDB Length = 390 Score = 31.6 bits (70), Expect = 0.43, Method: Compositional matrix adjust. Identities = 14/39 (35%), Positives = 21/39 (53%) Query: 28 KHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKS 66 K + ++G G GA I + A GH V ++DQ + I S Sbjct: 4 KKILIVGAGFSGAVIGRQLAEKGHQVHIIDQRDHIGGNS 42 >2EL7-A nrPDB Length = 337 Score = 31.2 bits (69), Expect = 0.61, Method: Compositional matrix adjust. Identities = 15/33 (45%), Positives = 23/33 (69%), Gaps = 1/33 (3%) Query: 217 FIVNRLLVPYLMEAIR-LYERGDASKEDIDTAM 248 ++V R+L +LMEA+R + ER +A K+D D M Sbjct: 268 YVVKRILFDHLMEALRPIRERAEALKKDPDYVM 300 >5X1Y-B nrPDB Length = 554 Score = 30.8 bits (68), Expect = 0.84, Method: Compositional matrix adjust. Identities = 18/53 (33%), Positives = 29/53 (54%) Query: 24 KIIVKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRK 76 K I K +TVIG G +G + Q+ G + L+ ++E +L + I ES+ K Sbjct: 246 KKIPKRLTVIGSGYIGMELGQLFHHLGSEITLMQRSERLLKEYDPEISESVEK 298 >3CGD-A nrPDB Length = 480 Score = 30.8 bits (68), Expect = 0.90, Method: Compositional matrix adjust. Identities = 30/101 (29%), Positives = 49/101 (48%), Gaps = 15/101 (14%) Query: 27 VKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKKF---- 82 V+ VT+IGGG +G +A+ G V ++++ + I + E + K A K Sbjct: 186 VEDVTIIGGGAIGLEMAETFVELGKKVRMIERNDHIGTIYDGDMAEYIYKEADKHHIEIL 245 Query: 83 -AENLKA--GDEFVEKTLSTIATSTDAASVVHSTDLVVEAI 120 EN+KA G+E VE A TD + + DLV+ ++ Sbjct: 246 TNENVKAFKGNERVE------AVETDKGT--YKADLVLVSV 278 >1PS9-A nrPDB Length = 671 Score = 29.6 bits (65), Expect = 1.7, Method: Compositional matrix adjust. Identities = 26/78 (33%), Positives = 34/78 (43%), Gaps = 14/78 (17%) Query: 28 KHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDI-----LAKSKKGIEESLRKVAKKKF 82 K++ V+G G G A AAA GH V L D +I +AK G EE F Sbjct: 374 KNLAVVGAGPAGLAFAINAAARGHQVTLFDAHSEIGGQFNIAKQIPGKEE---------F 424 Query: 83 AENLKAGDEFVEKTLSTI 100 E L+ +E T T+ Sbjct: 425 YETLRYYRRMIEVTGVTL 442 >2EQ6-A nrPDB Length = 464 Score = 29.3 bits (64), Expect = 2.3, Method: Compositional matrix adjust. Identities = 19/66 (28%), Positives = 33/66 (50%) Query: 16 STASASAKKIIVKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLR 75 ST + ++ + K + VIGGG +G + QV G V L++ +IL + LR Sbjct: 158 STRALKVEEGLPKRLLVIGGGAVGLELGQVYRRLGAEVTLIEYMPEILPQGDPETAALLR 217 Query: 76 KVAKKK 81 + +K+ Sbjct: 218 RALEKE 223 >2NQR-A nrPDB Length = 411 Score = 29.3 bits (64), Expect = 2.6, Method: Compositional matrix adjust. Identities = 25/70 (35%), Positives = 35/70 (50%), Gaps = 6/70 (8%) Query: 186 TPMTSQKTFESLVDFSKALGKHPVSCKDTPGFIVNRLLVPYLMEAIRLYERGDASKEDID 245 TP+T+Q+T + F + L VS D PGF N + Y A+RL + AS + + Sbjct: 22 TPLTAQETLPLVQCFGRILASDVVSPLDVPGFD-NSAMDGY---AVRLAD--IASGQPLP 75 Query: 246 TAMKLGAGYP 255 A K AG P Sbjct: 76 VAGKSFAGQP 85 >3ICS-A nrPDB Length = 588 Score = 28.5 bits (62), Expect = 3.8, Method: Compositional matrix adjust. Identities = 15/55 (27%), Positives = 26/55 (47%) Query: 9 MRSVSSSSTASASAKKIIVKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDIL 63 +R+V + A + +H TVIGGG +G + + G V LV+ ++ Sbjct: 169 LRNVPDTDRIKAYIDEKKPRHATVIGGGFIGVEMVENLRERGIEVTLVEMANQVM 223 >3FG2-P nrPDB Length = 404 Score = 28.5 bits (62), Expect = 4.1, Method: Compositional matrix adjust. Identities = 15/38 (39%), Positives = 21/38 (55%) Query: 28 KHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAK 65 KHV VIG G +G A A A G V +V+ ++A+ Sbjct: 143 KHVVVIGAGFIGLEFAATARAKGLEVDVVELAPRVMAR 180 >5Y77-A nrPDB Length = 473 Score = 28.5 bits (62), Expect = 4.3, Method: Compositional matrix adjust. Identities = 13/34 (38%), Positives = 20/34 (58%) Query: 28 KHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTED 61 + VT+IG GL G +A++ A G V L ++ D Sbjct: 9 RQVTIIGAGLAGTLVARLLARNGWQVNLFERRPD 42 >4FS8-A nrPDB Length = 383 Score = 28.1 bits (61), Expect = 4.8, Method: Compositional matrix adjust. Identities = 29/116 (25%), Positives = 48/116 (41%), Gaps = 18/116 (15%) Query: 35 GGLMGAGIAQVAAATGHTVVL-------------VDQTEDILAKSKKGIEESLRKVAKKK 81 G L GA + + TG V L VD ++ L ++K +E A+K Sbjct: 80 GSLEGATVLDLGCGTGRDVYLASKLVGEHGKVIGVDMLDNQLEVARKYVEYH----AEKF 135 Query: 82 FAENLKAGDEFVEKTLSTIATSTDAASVVHSTDLVVEAIVENLKV-KNELFKRLDK 136 F ++ F++ + +AT+ S D+V+ V NL K LFK + + Sbjct: 136 FGSPSRSNVRFLKGFIENLATAEPEGVPDSSVDIVISNCVCNLSTNKLALFKEIHR 191 >2UYY-A nrPDB Length = 316 Score = 27.7 bits (60), Expect = 6.4, Method: Compositional matrix adjust. Identities = 17/48 (35%), Positives = 25/48 (52%), Gaps = 3/48 (6%) Query: 28 KHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLR 75 K + +G GLMG+GI GHTV + ++T + K I+E R Sbjct: 31 KKIGFLGLGLMGSGIVSNLLKMGHTVTVWNRTAE---KCDLFIQEGAR 75 >1LSS-A nrPDB Length = 140 Score = 27.3 bits (59), Expect = 7.9, Method: Compositional matrix adjust. Identities = 13/43 (30%), Positives = 25/43 (58%) Query: 29 HVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIE 71 ++ + G G +G +A+ + GH +VL+D +DI K+ I+ Sbjct: 6 YIIIAGIGRVGYTLAKSLSEKGHDIVLIDIDKDICKKASAEID 48 >3KKJ-A nrPDB Length = 336 Score = 27.3 bits (59), Expect = 9.1, Method: Compositional matrix adjust. Identities = 12/31 (38%), Positives = 17/31 (54%) Query: 30 VTVIGGGLMGAGIAQVAAATGHTVVLVDQTE 60 + +IG G+ G AQ A GH V L D++ Sbjct: 5 IAIIGTGIAGLSAAQALTAAGHQVHLFDKSR 35 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 1F14-A nrPDB 424 e-119 3HDH-A nrPDB 403 e-113 4J0E-A nrPDB 365 e-101 6ACQ-A nrPDB 354 2e-98 1ZCJ-A nrPDB 349 7e-97 4KUG-A nrPDB 349 1e-96 3ZWA-A nrPDB 347 3e-96 4PZE-A nrPDB 330 3e-91 3MOG-A nrPDB 329 1e-90 5ZRV-A nrPDB 314 4e-86 4B3J-A nrPDB 312 1e-85 6HRD-A nrPDB 310 4e-85 6IUM-B nrPDB 310 4e-85 2WTB-A nrPDB 296 1e-80 4OM8-A nrPDB 288 2e-78 4DYD-A nrPDB 285 1e-77 3K6J-A nrPDB 285 2e-77 2D3T-A nrPDB 269 9e-73 1ZEJ-A nrPDB 264 3e-71 3F3S-A nrPDB 258 3e-69 3ADO-A nrPDB 233 1e-61 3CTV-A nrPDB 59 3e-09 Sequences not found previously or not previously below threshold: 2BC1-A nrPDB 48 7e-06 3PLN-A nrPDB 44 8e-05 4R16-A nrPDB 44 1e-04 1MV8-A nrPDB 42 3e-04 2GF2-A nrPDB 42 3e-04 4WJI-A nrPDB 42 4e-04 4A7P-A nrPDB 42 4e-04 5U8W-A nrPDB 41 5e-04 5ER0-A nrPDB 41 6e-04 3OJO-A nrPDB 41 7e-04 3KVE-A nrPDB 40 0.002 5X6R-A nrPDB 39 0.002 4D3F-A nrPDB 39 0.004 1REO-A nrPDB 39 0.004 1F8S-A nrPDB 39 0.004 6ABJ-A nrPDB 37 0.008 3X2F-A nrPDB 37 0.009 3GGO-A nrPDB 37 0.009 6AON-A nrPDB 37 0.009 5JE8-A nrPDB 37 0.010 4XRR-A nrPDB 37 0.011 1PS9-A nrPDB 37 0.013 3G5Q-A nrPDB 37 0.013 3H2Z-A nrPDB 37 0.013 4OQZ-A nrPDB 37 0.013 2G5C-A nrPDB 37 0.014 1VPD-A nrPDB 37 0.015 6BZ0-A nrPDB 37 0.015 3VTF-A nrPDB 36 0.016 3FG2-P nrPDB 36 0.019 2VHY-A nrPDB 36 0.021 2UYY-A nrPDB 36 0.021 3LAD-A nrPDB 36 0.022 6CI9-A nrPDB 36 0.022 3ZHB-A nrPDB 36 0.023 5JFC-L nrPDB 36 0.025 2EQ6-A nrPDB 36 0.025 3DC2-A nrPDB 36 0.026 2HMT-A nrPDB 36 0.026 5BUT-A nrPDB 35 0.027 4DLA-A nrPDB 35 0.027 5MH6-A nrPDB 35 0.029 4J90-A nrPDB 35 0.030 5ZIK-A nrPDB 35 0.036 3G0O-A nrPDB 35 0.036 5DT9-A nrPDB 35 0.038 3LXD-A nrPDB 35 0.040 2YQ5-A nrPDB 35 0.041 3NJ4-A nrPDB 35 0.047 4E21-A nrPDB 35 0.048 5Y77-A nrPDB 35 0.048 5JXW-A nrPDB 35 0.048 4PRK-A nrPDB 35 0.049 6C6P-A nrPDB 35 0.055 1HL3-A nrPDB 35 0.058 1QO8-A nrPDB 34 0.061 4A6N-B nrPDB 34 0.065 5N2I-A nrPDB 34 0.067 2W8Z-A nrPDB 34 0.068 3DAF-A nrPDB 34 0.071 5UYY-A nrPDB 34 0.077 1SEZ-A nrPDB 34 0.083 3ZZN-A nrPDB 34 0.084 4FFM-A nrPDB 34 0.085 1CF2-P nrPDB 34 0.091 5TR3-A nrPDB 34 0.11 4OQY-A nrPDB 34 0.11 3K30-A nrPDB 34 0.11 4OH1-A nrPDB 34 0.12 1LTH-T nrPDB 33 0.14 4HTF-A nrPDB 33 0.14 2EEZ-A nrPDB 33 0.15 3WFI-A nrPDB 33 0.15 2DFV-A nrPDB 33 0.15 2PA3-A nrPDB 33 0.15 1AHH-A nrPDB 33 0.15 3H5A-A nrPDB 33 0.15 3WSV-A nrPDB 33 0.16 4ND4-A nrPDB 33 0.16 3HWR-A nrPDB 33 0.16 5OCM-A nrPDB 33 0.16 2EW2-A nrPDB 33 0.17 3PEF-A nrPDB 33 0.18 2AVN-A nrPDB 33 0.18 1Q1R-A nrPDB 33 0.20 1V9L-A nrPDB 33 0.20 2CZG-A nrPDB 33 0.20 2V3B-A nrPDB 33 0.21 4UEJ-A nrPDB 33 0.21 4ZGS-A nrPDB 33 0.22 3Q3C-A nrPDB 33 0.22 4ZCC-A nrPDB 33 0.22 3KKJ-A nrPDB 33 0.23 3TL2-A nrPDB 32 0.23 1A5Z-A nrPDB 32 0.25 3UPY-A nrPDB 32 0.27 5VJ7-A nrPDB 32 0.31 3KB6-A nrPDB 32 0.32 3DOJ-A nrPDB 32 0.35 4JJI-A nrPDB 32 0.36 3ATQ-A nrPDB 32 0.38 5X68-A nrPDB 32 0.39 3ETH-A nrPDB 32 0.39 3PDU-A nrPDB 32 0.41 1YB4-A nrPDB 32 0.42 4TSK-A nrPDB 32 0.44 4K28-A nrPDB 32 0.44 1C0L-A nrPDB 32 0.45 4MIE-A nrPDB 32 0.46 2R9Z-A nrPDB 32 0.47 3D2L-A nrPDB 32 0.49 2OME-A nrPDB 31 0.53 3KYB-A nrPDB 31 0.55 1GPJ-A nrPDB 31 0.56 6APH-A nrPDB 31 0.58 4PLF-A nrPDB 31 0.63 3BHF-A nrPDB 31 0.63 6IHE-A nrPDB 31 0.70 5A9T-A nrPDB 31 0.72 1PZF-A nrPDB 31 0.74 4K22-A nrPDB 31 0.77 3N58-A nrPDB 31 0.77 3L6D-A nrPDB 31 0.78 3G79-A nrPDB 31 0.84 3QHA-A nrPDB 31 0.85 6FQY-A nrPDB 30 0.91 5T5Q-A nrPDB 30 0.94 6GGU-A nrPDB 30 0.96 5O3Z-A nrPDB 30 0.99 5J7X-A nrPDB 30 1.1 2P4Q-A nrPDB 30 1.2 1ZOV-A nrPDB 30 1.2 3IHG-A nrPDB 30 1.2 5G6R-A nrPDB 30 1.2 3ICS-A nrPDB 30 1.2 1X0X-A nrPDB 30 1.3 5VDN-A nrPDB 30 1.3 3DO5-A nrPDB 30 1.3 3OC4-A nrPDB 30 1.3 2HQM-A nrPDB 30 1.3 1X14-A nrPDB 30 1.4 4EMJ-A nrPDB 30 1.4 1LSS-A nrPDB 30 1.5 3VH2-A nrPDB 30 1.6 3T7E-A nrPDB 30 1.6 3CKY-A nrPDB 30 1.7 2RIR-A nrPDB 30 1.7 5W4C-A nrPDB 30 1.7 4D3S-A nrPDB 30 1.7 4IV9-A nrPDB 30 1.8 1J49-A nrPDB 30 1.8 5EVY-X nrPDB 30 1.8 1OOE-A nrPDB 30 1.8 5NMX-A nrPDB 30 1.9 3FR8-A nrPDB 30 1.9 5MIU-A nrPDB 29 2.0 3ENK-A nrPDB 29 2.0 5YEQ-A nrPDB 29 2.1 5FLX-A nrPDB 29 2.1 4UJC-CA nrPDB 29 2.1 3BCH-A nrPDB 29 2.1 1UZM-A nrPDB 29 2.2 3I83-A nrPDB 29 2.3 3WTC-A nrPDB 29 2.3 5XVH-A nrPDB 29 2.4 3GVH-A nrPDB 29 2.4 4MOP-A nrPDB 29 2.4 4WEQ-A nrPDB 29 2.4 4RQU-A nrPDB 29 2.4 2HJR-A nrPDB 29 2.5 2ZYA-A nrPDB 29 2.5 3L76-A nrPDB 29 2.6 5INT-A nrPDB 29 2.6 5VVW-A nrPDB 29 2.8 6JCV-A nrPDB 29 2.8 3G1U-A nrPDB 29 2.8 4IZO-A nrPDB 29 2.9 5AYV-A nrPDB 29 3.0 5U1O-A nrPDB 29 3.1 3FCA-A nrPDB 29 3.1 5Y8M-A nrPDB 29 3.3 4GBJ-A nrPDB 29 3.4 3X0V-A nrPDB 29 3.5 1K4P-A nrPDB 29 3.5 4IQE-A nrPDB 29 3.6 6EOI-A nrPDB 29 3.8 5FDN-A nrPDB 29 3.9 3PII-A nrPDB 29 3.9 1XDW-A nrPDB 29 3.9 4CPD-A nrPDB 29 4.1 2EKL-A nrPDB 28 4.5 4Z6K-A nrPDB 28 4.9 4DGS-A nrPDB 28 5.0 3IK4-A nrPDB 28 5.7 1QYC-A nrPDB 28 5.9 3VPX-A nrPDB 28 6.3 4EEZ-A nrPDB 28 6.7 4E4T-A nrPDB 28 6.8 4AVY-A nrPDB 28 7.1 4DIO-A nrPDB 27 7.5 2IZ1-A nrPDB 27 7.5 3RWB-A nrPDB 27 8.4 1JAY-A nrPDB 27 8.6 3A28-C nrPDB 27 8.7 >1F14-A nrPDB Length = 310 Score = 424 bits (1090), Expect = e-119, Method: Composition-based stats. Identities = 300/302 (99%), Positives = 300/302 (99%) Query: 13 SSSSTASASAKKIIVKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEE 72 SSSSTASASAKKIIVKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEE Sbjct: 1 SSSSTASASAKKIIVKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEE 60 Query: 73 SLRKVAKKKFAENLKAGDEFVEKTLSTIATSTDAASVVHSTDLVVEAIVENLKVKNELFK 132 SLRKVAKKKFAEN KAGDE VEKTLSTIATSTDAASVVHSTDLVVEAIVENLKVKNELFK Sbjct: 61 SLRKVAKKKFAENPKAGDECVEKTLSTIATSTDAASVVHSTDLVVEAIVENLKVKNELFK 120 Query: 133 RLDKFAAEHTIFASNTSSLQITSIANATTRQDRFAGLHFFNPVPVMKLVEVIKTPMTSQK 192 RLDKFAAEHTIFASNTSSLQITSIANATTRQDRFAGLHFFNPVPVMKLVEVIKTPMTSQK Sbjct: 121 RLDKFAAEHTIFASNTSSLQITSIANATTRQDRFAGLHFFNPVPVMKLVEVIKTPMTSQK 180 Query: 193 TFESLVDFSKALGKHPVSCKDTPGFIVNRLLVPYLMEAIRLYERGDASKEDIDTAMKLGA 252 TFESLVDFSKALGKHPVSCKDTPGFIVNRLLVPYLMEAIRLYERGDASKEDIDTAMKLGA Sbjct: 181 TFESLVDFSKALGKHPVSCKDTPGFIVNRLLVPYLMEAIRLYERGDASKEDIDTAMKLGA 240 Query: 253 GYPMGPFELLDYVGLDTTKFIVDGWHEMDAENPLHQPSPSLNKLVAENKFGKKTGEGFYK 312 GYPMGPFELLDYVGLDTTKFIVDGWHEMDAENPLHQPSPSLNKLVAENKFGKKTGEGFYK Sbjct: 241 GYPMGPFELLDYVGLDTTKFIVDGWHEMDAENPLHQPSPSLNKLVAENKFGKKTGEGFYK 300 Query: 313 YK 314 YK Sbjct: 301 YK 302 >3HDH-A nrPDB Length = 302 Score = 403 bits (1035), Expect = e-113, Method: Composition-based stats. Identities = 274/292 (93%), Positives = 288/292 (98%) Query: 23 KKIIVKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKKF 82 KKI+VKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKKF Sbjct: 11 KKILVKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKKF 70 Query: 83 AENLKAGDEFVEKTLSTIATSTDAASVVHSTDLVVEAIVENLKVKNELFKRLDKFAAEHT 142 AEN KAGDEFVEKTLS+I+TSTDAASVVHSTDLVVEAIVENLKVK+ELFKRLDKFAAEHT Sbjct: 71 AENPKAGDEFVEKTLSSISTSTDAASVVHSTDLVVEAIVENLKVKSELFKRLDKFAAEHT 130 Query: 143 IFASNTSSLQITSIANATTRQDRFAGLHFFNPVPVMKLVEVIKTPMTSQKTFESLVDFSK 202 IFASNTSSLQITS+ANATTRQDRFAGLHFFNPVP+MKLVEV+KTPMTSQKT ESLVDFSK Sbjct: 131 IFASNTSSLQITSLANATTRQDRFAGLHFFNPVPLMKLVEVVKTPMTSQKTLESLVDFSK 190 Query: 203 ALGKHPVSCKDTPGFIVNRLLVPYLMEAIRLYERGDASKEDIDTAMKLGAGYPMGPFELL 262 LGKHPVSCKDTPGFIVNRLLVPYL+EA+RLYERGDASKEDIDTAMKLGAGYPMGPFELL Sbjct: 191 TLGKHPVSCKDTPGFIVNRLLVPYLIEAVRLYERGDASKEDIDTAMKLGAGYPMGPFELL 250 Query: 263 DYVGLDTTKFIVDGWHEMDAENPLHQPSPSLNKLVAENKFGKKTGEGFYKYK 314 DYVGLDTTKFI+DGWHEMD++NPL QPSP++NKLVAENKFGKKTGEGFYKYK Sbjct: 251 DYVGLDTTKFIIDGWHEMDSQNPLFQPSPAMNKLVAENKFGKKTGEGFYKYK 302 >4J0E-A nrPDB Length = 320 Score = 365 bits (937), Expect = e-101, Method: Composition-based stats. Identities = 143/300 (47%), Positives = 204/300 (68%), Gaps = 1/300 (0%) Query: 15 SSTASASAKKIIVKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESL 74 S +A +++V ++G G MG+GIAQV A++G V+L D + L ++ K I +S+ Sbjct: 2 GSMFTAKCAMQNIRNVAIVGSGQMGSGIAQVTASSGFNVMLADVNKKALDRAMKAISQSV 61 Query: 75 RKVAKKKFAENLKAGDEFVEKTLSTIATSTDAASVVHSTDLVVEAIVENLKVKNELFKRL 134 ++KK+ + K +FV T+S I T + ++ V DL++EA +EN+ +K +F ++ Sbjct: 62 THLSKKQKGTD-KEKSDFVTLTMSRIKTCNNVSTAVADADLIIEAAIENIDLKRGIFAQI 120 Query: 135 DKFAAEHTIFASNTSSLQITSIANATTRQDRFAGLHFFNPVPVMKLVEVIKTPMTSQKTF 194 ++ + +I +NTSS + +A + RF GLHFFNPVPVMKL+EVI++ TS +T+ Sbjct: 121 EQSCKKDSILTTNTSSFLLEDVAKGLQDKTRFGGLHFFNPVPVMKLLEVIRSDDTSDETY 180 Query: 195 ESLVDFSKALGKHPVSCKDTPGFIVNRLLVPYLMEAIRLYERGDASKEDIDTAMKLGAGY 254 +L+ F A+GK V+CKD+PGFIVNRLL+PY EA R+YERGDAS DID AMKLGAG+ Sbjct: 181 ATLIKFGTAVGKTTVACKDSPGFIVNRLLIPYFFEAARMYERGDASMTDIDEAMKLGAGH 240 Query: 255 PMGPFELLDYVGLDTTKFIVDGWHEMDAENPLHQPSPSLNKLVAENKFGKKTGEGFYKYK 314 PMGPFEL DY+GLDT KF++DGW E L + SP ++KLVAE K G+KTG+GFY YK Sbjct: 241 PMGPFELADYIGLDTVKFVMDGWAAKYPEVQLFEASPLVDKLVAEGKLGRKTGDGFYSYK 300 >6ACQ-A nrPDB Length = 302 Score = 354 bits (909), Expect = 2e-98, Method: Composition-based stats. Identities = 127/287 (44%), Positives = 178/287 (62%), Gaps = 7/287 (2%) Query: 27 VKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKKFAENL 86 +K V VIG G MG+GIAQ AA G VVL D ++ + + I ++L K+ KK Sbjct: 21 MKKVCVIGAGTMGSGIAQAFAAKGFEVVLRDIKDEFVDRGLDFINKNLSKLVKK-----G 75 Query: 87 KAGDEFVEKTLSTIATSTDAASVVHSTDLVVEAIVENLKVKNELFKRLDKFAAEHTIFAS 146 K + + L+ I+ + D ++ DLV+EA VE + +K ++F LD TI AS Sbjct: 76 KIEEATKVEILTRISGTVDL-NMAADCDLVIEAAVERMDIKKQIFADLDNICKPETILAS 134 Query: 147 NTSSLQITSIANATTRQDRFAGLHFFNPVPVMKLVEVIKTPMTSQKTFESLVDFSKALGK 206 NTSSL IT +A+AT R D+ G+HFFNP PVMKLVEVI+ TSQ+TF+++ + S A+GK Sbjct: 135 NTSSLSITEVASATKRPDKVIGMHFFNPAPVMKLVEVIRGIATSQETFDAVKETSIAIGK 194 Query: 207 HPVSCKDTPGFIVNRLLVPYLMEAIRLYERGDASKEDIDTAMKLGAGYPMGPFELLDYVG 266 PV + PGF+VNR+L+P + EA+ + G AS EDID AMKLGA +PMGP EL D++G Sbjct: 195 DPVEVAEAPGFVVNRILIPMINEAVGILAEGIASVEDIDKAMKLGANHPMGPLELGDFIG 254 Query: 267 LDTTKFIVDGWHEMDAENPLHQPSPSLNKLVAENKFGKKTGEGFYKY 313 LD I+D + ++ ++P L K V G+K+G+GFY Y Sbjct: 255 LDICLAIMDVLYSETGDSK-YRPHTLLKKYVRAGWLGRKSGKGFYDY 300 >1ZCJ-A nrPDB Length = 463 Score = 349 bits (896), Expect = 7e-97, Method: Composition-based stats. Identities = 104/310 (33%), Positives = 152/310 (49%), Gaps = 21/310 (6%) Query: 13 SSSSTASASAKKIIVKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEE 72 S +S +ASA+ V V V+G G MG GIA A G +VV V+ L +KK I Sbjct: 25 SGASWKTASAQP--VSSVGVLGLGTMGRGIAISFARVGISVVAVESDPKQLDAAKKIITF 82 Query: 73 SLRKVAKKKFAENLKAGDEFVEKTLSTIATSTDAASVVHSTDLVVEAIVENLKVKNELFK 132 +L K A + + + + ST ST DLVVEA+ E++ +K ++F Sbjct: 83 TLEKEASRAHQNGQASAKPKLRFSSSTKELST--------VDLVVEAVFEDMNLKKKVFA 134 Query: 133 RLDKFAAEHTIFASNTSSLQITSIANATTRQDRFAGLHFFNPVPVMKLVEVIKTPMTSQK 192 L +NTS+L + IA++T R G HFF+P VM+L+EVI + +S Sbjct: 135 ELSALCKPGAFLCTNTSALNVDDIASSTDRPQLVIGTHFFSPAHVMRLLEVIPSRYSSPT 194 Query: 193 TFESLVDFSKALGKHPVSCKDTPGFIVNRLLVPYLMEAIRLYERGDASKEDIDTAMKLGA 252 T +++ SK +GK V + GF+ NR+L PY + L E G + ED+D ++ Sbjct: 195 TIATVMSLSKKIGKIGVVVGNCYGFVGNRMLAPYYNQGFFLLEEG-SKPEDVDGVLE-EF 252 Query: 253 GYPMGPFELLDYVGLDTTKFIVDGWHEMDAENPLHQP---------SPSLNKLVAENKFG 303 G+ MGPF + D GLD I G P P SP + L +FG Sbjct: 253 GFKMGPFRVSDLAGLDVGWKIRKGQGLTGPSLPPGTPVRKRGNSRYSPLGDMLCEAGRFG 312 Query: 304 KKTGEGFYKY 313 +KTG+G+Y+Y Sbjct: 313 QKTGKGWYQY 322 Score = 58.2 bits (139), Expect = 4e-09, Method: Composition-based stats. Identities = 28/87 (32%), Positives = 40/87 (45%), Gaps = 4/87 (4%) Query: 218 IVNRLLVPYLMEAIRLYERGD-ASKEDIDTAMKLGAGYPM---GPFELLDYVGLDTTKFI 273 I+ R L + EA R+ E G A E ID G G+P GP VGL T Sbjct: 359 ILERCLYSLINEAFRILEEGMAARPEHIDVIYLHGYGWPRHKGGPMFYAASVGLPTVLEK 418 Query: 274 VDGWHEMDAENPLHQPSPSLNKLVAEN 300 + ++ + + P +PS L +LVA+ Sbjct: 419 LQKYYRQNPDIPQLEPSDYLRRLVAQG 445 >4KUG-A nrPDB Length = 290 Score = 349 bits (895), Expect = 1e-96, Method: Composition-based stats. Identities = 129/287 (44%), Positives = 178/287 (62%), Gaps = 7/287 (2%) Query: 27 VKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKKFAENL 86 +K V V+G G MGAGI Q AA G V++ D E+ + + I +SL K+ K+ Sbjct: 1 MKKVFVLGAGTMGAGIVQAFAAKGCEVIVRDIKEEFVDRGIATITKSLSKLVAKE----- 55 Query: 87 KAGDEFVEKTLSTIATSTDAASVVHSTDLVVEAIVENLKVKNELFKRLDKFAAEHTIFAS 146 K + E+ LS I+ +TD + DLVVEA +EN+K+K E+F LD TI AS Sbjct: 56 KITEADKEEILSRISGTTDM-KLAADCDLVVEAAIENMKIKKEIFAELDGICKPETILAS 114 Query: 147 NTSSLQITSIANATTRQDRFAGLHFFNPVPVMKLVEVIKTPMTSQKTFESLVDFSKALGK 206 NTSSL IT +A+AT R D+ G+HFFNP PVMKLVEVI+ TSQ+TF+++ + S+++GK Sbjct: 115 NTSSLSITEVASATKRADKVIGMHFFNPAPVMKLVEVIRGAATSQETFDAVKEMSESIGK 174 Query: 207 HPVSCKDTPGFIVNRLLVPYLMEAIRLYERGDASKEDIDTAMKLGAGYPMGPFELLDYVG 266 PV + PGF+VNR+L+P + EA + + G A +EDID AMKLGA +PMGP L D +G Sbjct: 175 TPVEVAEAPGFVVNRILIPMINEATFILQEGVAKEEDIDAAMKLGANHPMGPLALGDLIG 234 Query: 267 LDTTKFIVDGWHEMDAENPLHQPSPSLNKLVAENKFGKKTGEGFYKY 313 LD I+D + + ++ S L K V G+KTG+GFY Y Sbjct: 235 LDVCLAIMDVLYNETGDTK-YRASSLLRKYVRAGWLGRKTGKGFYDY 280 >3ZWA-A nrPDB Length = 742 Score = 347 bits (891), Expect = 3e-96, Method: Composition-based stats. Identities = 104/310 (33%), Positives = 152/310 (49%), Gaps = 21/310 (6%) Query: 13 SSSSTASASAKKIIVKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEE 72 S +S +ASA+ V V V+G G MG GIA A G +VV V+ L +KK I Sbjct: 304 SGASWKTASAQP--VSSVGVLGLGTMGRGIAISFARVGISVVAVESDPKQLDAAKKIITF 361 Query: 73 SLRKVAKKKFAENLKAGDEFVEKTLSTIATSTDAASVVHSTDLVVEAIVENLKVKNELFK 132 +L K A + + + + ST ST DLVVEA+ E++ +K ++F Sbjct: 362 TLEKEASRAHQNGQASAKPKLRFSSSTKELST--------VDLVVEAVFEDMNLKKKVFA 413 Query: 133 RLDKFAAEHTIFASNTSSLQITSIANATTRQDRFAGLHFFNPVPVMKLVEVIKTPMTSQK 192 L +NTS+L + IA++T R G HFF+P VM+L+EVI + +S Sbjct: 414 ELSALCKPGAFLCTNTSALNVDDIASSTDRPQLVIGTHFFSPAHVMRLLEVIPSRYSSPT 473 Query: 193 TFESLVDFSKALGKHPVSCKDTPGFIVNRLLVPYLMEAIRLYERGDASKEDIDTAMKLGA 252 T +++ SK +GK V + GF+ NR+L PY + L E G + ED+D ++ Sbjct: 474 TIATVMSLSKKIGKIGVVVGNCYGFVGNRMLAPYYNQGFFLLEEG-SKPEDVDGVLE-EF 531 Query: 253 GYPMGPFELLDYVGLDTTKFIVDGWHEMDAENPLHQP---------SPSLNKLVAENKFG 303 G+ MGPF + D GLD I G P P SP + L +FG Sbjct: 532 GFKMGPFRVSDLAGLDVGWKIRKGQGLTGPSLPPGTPVRKRGNSRYSPLGDMLCEAGRFG 591 Query: 304 KKTGEGFYKY 313 +KTG+G+Y+Y Sbjct: 592 QKTGKGWYQY 601 Score = 58.2 bits (139), Expect = 5e-09, Method: Composition-based stats. Identities = 28/87 (32%), Positives = 40/87 (45%), Gaps = 4/87 (4%) Query: 218 IVNRLLVPYLMEAIRLYERGD-ASKEDIDTAMKLGAGYPM---GPFELLDYVGLDTTKFI 273 I+ R L + EA R+ E G A E ID G G+P GP VGL T Sbjct: 638 ILERCLYSLINEAFRILEEGMAARPEHIDVIYLHGYGWPRHKGGPMFYAASVGLPTVLEK 697 Query: 274 VDGWHEMDAENPLHQPSPSLNKLVAEN 300 + ++ + + P +PS L +LVA+ Sbjct: 698 LQKYYRQNPDIPQLEPSDYLRRLVAQG 724 >4PZE-A nrPDB Length = 284 Score = 330 bits (847), Expect = 3e-91, Method: Composition-based stats. Identities = 114/287 (39%), Positives = 171/287 (59%), Gaps = 7/287 (2%) Query: 27 VKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKKFAENL 86 ++ V ++G G MG GIAQ A G VV+VD ++ + K + SL ++ KK+ Sbjct: 3 IRTVGIVGAGTMGNGIAQACAVVGLNVVMVDISDAAVQKGVATVASSLDRLIKKEKLTEA 62 Query: 87 KAGDEFVEKTLSTIATSTDAASVVHSTDLVVEAIVENLKVKNELFKRLDKFAAEHTIFAS 146 L+ I ST + +TD+V+EA EN +K ++ K++D E+ I AS Sbjct: 63 DKAS-----ALARIKGSTSYDDL-KATDIVIEAATENYDLKVKILKQIDGIVGENVIIAS 116 Query: 147 NTSSLQITSIANATTRQDRFAGLHFFNPVPVMKLVEVIKTPMTSQKTFESLVDFSKALGK 206 NTSS+ IT +A T+R DRF G+HFFNPVPVM LVE+I+ TS T ++ SK LGK Sbjct: 117 NTSSISITKLAAVTSRADRFIGMHFFNPVPVMALVELIRGLQTSDTTHAAVEALSKQLGK 176 Query: 207 HPVSCKDTPGFIVNRLLVPYLMEAIRLYERGDASKEDIDTAMKLGAGYPMGPFELLDYVG 266 +P++ K++PGF+VNR+L P + EA + G AS E+ID MKLG +P+GP L D +G Sbjct: 177 YPITVKNSPGFVVNRILCPMINEAFCVLGEGLASPEEIDEGMKLGCNHPIGPLALADMIG 236 Query: 267 LDTTKFIVDGWHEMDAENPLHQPSPSLNKLVAENKFGKKTGEGFYKY 313 LDT +++ + + +P ++P+ + ++VA G+KTG G Y Y Sbjct: 237 LDTMLAVMEVLY-TEFADPKYRPAMLMREMVAAGYLGRKTGRGVYVY 282 >3MOG-A nrPDB Length = 483 Score = 329 bits (843), Expect = 1e-90, Method: Composition-based stats. Identities = 118/288 (40%), Positives = 158/288 (54%), Gaps = 6/288 (2%) Query: 27 VKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKKFAENL 86 V+ V VIG G MGAGIA+VAA+ GH V+L D + + L ++ GI L Sbjct: 5 VQTVAVIGSGTMGAGIAEVAASHGHQVLLYDISAEALTRAIDGIHARLNSRV-----TRG 59 Query: 87 KAGDEFVEKTLSTIATSTDAASVVHSTDLVVEAIVENLKVKNELFKRLDKFAAEHTIFAS 146 K E E+TL + TD + + DLV+EA E L+VK LF +L + T+ + Sbjct: 60 KLTAETCERTLKRLIPVTDIH-ALAAADLVIEAASERLEVKKALFAQLAEVCPPQTLLTT 118 Query: 147 NTSSLQITSIANATTRQDRFAGLHFFNPVPVMKLVEVIKTPMTSQKTFESLVDFSKALGK 206 NTSS+ IT+IA +R AGLHFFNP PVMKLVEV+ T+ + E L + + + GK Sbjct: 119 NTSSISITAIAAEIKNPERVAGLHFFNPAPVMKLVEVVSGLATAAEVVEQLCELTLSWGK 178 Query: 207 HPVSCKDTPGFIVNRLLVPYLMEAIRLYERGDASKEDIDTAMKLGAGYPMGPFELLDYVG 266 PV C TPGFIVNR+ PY EA R E A+ E ID A++ GAG+PMGP EL D +G Sbjct: 179 QPVRCHSTPGFIVNRVARPYYSEAWRALEEQVAAPEVIDAALRDGAGFPMGPLELTDLIG 238 Query: 267 LDTTKFIVDGWHEMDAENPLHQPSPSLNKLVAENKFGKKTGEGFYKYK 314 D + + PS +LV + GKK+G G Y ++ Sbjct: 239 QDVNFAVTCSVFNAFWQERRFLPSLVQQELVIGGRLGKKSGLGVYDWR 286 Score = 67.8 bits (164), Expect = 6e-12, Method: Composition-based stats. Identities = 39/183 (21%), Positives = 74/183 (40%), Gaps = 16/183 (8%) Query: 117 VEAIVENLKVKNELFKRLDKFAAEHTIFASNTSSLQITSIANATTRQ----DRFAGLHFF 172 +EA+ ++ ++ K+ D + T ++A R D+ AG Sbjct: 295 LEAVSDSFS-PMKVEKKSDGVTEIDDVLLIETQGETAQALAIRLARPVVVIDKMAG---- 349 Query: 173 NPVPVMKLVEVIKTPMTSQKTFESLVDFSKALGKHPVSCKDTPGFIVNRLLVPYLMEAIR 232 K+V + + + + + GK + D PG ++ R + + EA+ Sbjct: 350 ------KVVTIAAAAVNPDSATRKAIYYLQQQGKTVLQIADYPGMLIWRTVAMIINEALD 403 Query: 233 LYERGDASKEDIDTAMKLGAGYPMGPFELLDYVGLDTTKFIVDGWHEMDAENPLHQPSPS 292 ++G AS++DIDTAM+LG YP GP +G +++ E ++P Sbjct: 404 ALQKGVASEQDIDTAMRLGVNYPYGPLAWGAQLGWQRILRLLENLQHHYGEE-RYRPCSL 462 Query: 293 LNK 295 L + Sbjct: 463 LRQ 465 >5ZRV-A nrPDB Length = 763 Score = 314 bits (804), Expect = 4e-86, Method: Composition-based stats. Identities = 97/294 (32%), Positives = 157/294 (53%), Gaps = 8/294 (2%) Query: 21 SAKKIIVKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKK 80 A + VKH+ ++G GLMGAGIAQV+ G +L D T L + ++ + + L KK Sbjct: 355 GAPQKDVKHLAILGAGLMGAGIAQVSVDKGLKTILKDATLTALDRGQQQVFKGLNDKVKK 414 Query: 81 KFAENLKAGDEFVEKTLSTIATSTDAASVVHSTDLVVEAIVENLKVKNELFKRLDKFAAE 140 K + + F S + D D+V+EA+ E+L +K+ + K ++ + Sbjct: 415 KALTSFERDSIF-----SNLTGQLDYQGF-EKADMVIEAVFEDLSLKHRVLKEVEAVIPD 468 Query: 141 HTIFASNTSSLQITSIANATTRQDRFAGLHFFNPVPVMKLVEVIKTPMTSQKTFESLVDF 200 H IFASNTS+L I+ IA + R ++ G+H+F+PV M+L+E+I T TS+ T S V Sbjct: 469 HCIFASNTSALPISEIAAVSKRPEKVIGMHYFSPVDKMQLLEIITTEKTSKDTSASAVAV 528 Query: 201 SKALGKHPVSCKDTPGFIVNRLLVPYLMEAIRLYERGDASKEDIDTAMKLGAGYPMGPFE 260 GK + KD PGF R L P + E IR+ + G + +D ++ G+P+G Sbjct: 529 GLKQGKVIIVVKDGPGFYTTRCLAPMMSEVIRILQEGV-DPKKLD-SLTTSFGFPVGAAT 586 Query: 261 LLDYVGLDTTKFIVDGWHEMDAENPLHQPSPSLNKLVAENKFGKKTGEGFYKYK 314 L+D VG+D K + + ++ E L ++V++ G+K+G+GFY Y+ Sbjct: 587 LVDEVGVDVAKHVAEDLGKVFGERFGGGNPELLTQMVSKGFLGRKSGKGFYIYQ 640 >4B3J-A nrPDB Length = 736 Score = 312 bits (799), Expect = 1e-85, Method: Composition-based stats. Identities = 98/311 (31%), Positives = 163/311 (52%), Gaps = 16/311 (5%) Query: 9 MRSVSSSSTASASAKKIIVKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKK 68 ++++++ + K +K + V+G G+MGAGIA V+A G+ VVL D + + AK K Sbjct: 323 LQAINAGGSRPEGIGKTPIKRIGVLGAGMMGAGIAYVSAKAGYEVVLKDVSLEAAAKGK- 381 Query: 69 GIEESLRKVAKKKFAENLKAGDEFVEKTLSTIATSTDAASVVHSTDLVVEAIVENLKVKN 128 + + K E + E + L+ I + DAA D V+EA+ EN ++K+ Sbjct: 382 ----GYSEKLEAKALERGRTTQERSDALLARITPTADAADF-KGVDFVIEAVFENQELKH 436 Query: 129 ELFKRLDKFAAEHTIFASNTSSLQITSIANATTRQDRFAGLHFFNPVPVMKLVEVIKTPM 188 ++F ++ + I SNTS+L IT +A RQ+ F G+HFF+PV M LVE+IK Sbjct: 437 KVFGEIEDIVEPNAILGSNTSTLPITGLATGVKRQEDFIGIHFFSPVDKMPLVEIIKGEK 496 Query: 189 TSQKTFESLVDFSKALGKHPVSCKDTPGFIVNRLLVPYLMEAIRLYERG--DASKEDIDT 246 TS + + D++ A+GK P+ D+ GF +R++ ++ EA+ + G AS E + Sbjct: 497 TSDEALARVFDYTLAIGKTPIVVNDSRGFFTSRVIGTFVNEALAMLGEGVEPASIEQAGS 556 Query: 247 AMKLGAGYPMGPFELLDYVGLDTTKFI-VDGWHEMDAENPLHQPSPS---LNKLVAENKF 302 AGYP P +L D + L+ I V ++ +QP P+ + K++ + Sbjct: 557 Q----AGYPAPPLQLSDELNLELMHKIAVATRKGVEDAGGTYQPHPAEAVVEKMIELGRS 612 Query: 303 GKKTGEGFYKY 313 G+ G GFY+Y Sbjct: 613 GRLKGAGFYEY 623 >6HRD-A nrPDB Length = 317 Score = 310 bits (795), Expect = 4e-85, Method: Composition-based stats. Identities = 119/290 (41%), Positives = 169/290 (58%), Gaps = 11/290 (3%) Query: 27 VKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESL-RKVAKKKFAEN 85 ++ V V+G G MG+GIA+V+A G V + + E ++ + I +SL R V+ K E Sbjct: 25 IQRVGVVGAGQMGSGIAEVSARAGVEVTVFEPAEALITAGRNRIVKSLERAVSAGKVTER 84 Query: 86 LKAGDEFVEKTLSTIATSTDAASVVHSTDLVVEAIVENLKVKNELFKRLDKFA-AEHTIF 144 + ++ L + +TD + LV+EA+VE+ VK+E+F LD+ + Sbjct: 85 ER------DRALGLLTFTTDLNDL-SDRQLVIEAVVEDEAVKSEIFAELDRVVTDPDAVL 137 Query: 145 ASNTSSLQITSIANATTRQDRFAGLHFFNPVPVMKLVEVIKTPMTSQKTFESLVDF-SKA 203 ASNTSS+ I +A AT + R GLHFFNPVPV+ LVE+++T +T + +F S Sbjct: 138 ASNTSSIPIMKVAAATKQPQRVLGLHFFNPVPVLPLVELVRTLVTDEAAAARTEEFASTV 197 Query: 204 LGKHPVSCKDTPGFIVNRLLVPYLMEAIRLYERGDASKEDIDTAMKLGAGYPMGPFELLD 263 LGK V C D GF+VN LLVPYL+ AIR+ E G A+ ED+D A+ G +PMGP L D Sbjct: 198 LGKQVVRCSDRSGFVVNALLVPYLLSAIRMVEAGFATVEDVDKAVVAGLSHPMGPLRLSD 257 Query: 264 YVGLDTTKFIVDGWHEMDAENPLHQPSPSLNKLVAENKFGKKTGEGFYKY 313 VGLDT K I D E + + P + P P L ++V + GKK+G GFY Y Sbjct: 258 LVGLDTLKLIADKMFE-EFKEPHYGPPPLLLRMVEAGQLGKKSGRGFYTY 306 >6IUM-B nrPDB Length = 701 Score = 310 bits (795), Expect = 4e-85, Method: Composition-based stats. Identities = 96/305 (31%), Positives = 150/305 (49%), Gaps = 11/305 (3%) Query: 10 RSVSSSSTASASAKKIIVKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKG 69 R+ S ++ V VIG G MG GI+ G V +++ ++ L + Sbjct: 275 RAASKIPDVPEGTPTRKIEKVAVIGAGTMGGGISMNFLNAGIPVTILETKQEALDRGVGI 334 Query: 70 IEESLRKVAKKKFAENLKAGDEFVEKTLSTIATSTDAASVVHSTDLVVEAIVENLKVKNE 129 I ++ AKK K E VE+ + ++T+ + DL++EA+ E + VK Sbjct: 335 IRKNYENSAKK-----GKLTQEKVEQRMGLLSTTLSYDDL-KDADLIIEAVFEEMGVKET 388 Query: 130 LFKRLDKFAAEHTIFASNTSSLQITSIANATTRQDRFAGLHFFNPVPVMKLVEVIKTPMT 189 +FK+LD+ A + I ASNTS+L + IA+ T R G+HFF+P VMKL+EV++ T Sbjct: 389 VFKKLDEVAKQGAILASNTSTLDVNKIASFTKRPQDVVGMHFFSPANVMKLLEVVRGEKT 448 Query: 190 SQKTFESLVDFSKALGKHPVSCKDTPGFIVNRLLVPYLMEAIRLYERGDASKEDIDTAMK 249 + +++ K + K V GFI NR++ Y +A L + G A E +D A++ Sbjct: 449 GKDVLATVMQVGKKIKKTAVVSGVCDGFIGNRMIEQYSRQAGYLLDEG-ALPEQVDKAIE 507 Query: 250 LGAGYPMGPFELLDYVGLDTTKFIVDGWHEMDAENPLHQPSPSLNKLVAENKFGKKTGEG 309 G+ MGPF + D G D I + P Q S + + L +FG+KTG G Sbjct: 508 -KFGFAMGPFRMGDLAGNDIGWAIR---KRRAVDKPEIQYSKTADLLCEMGRFGQKTGAG 563 Query: 310 FYKYK 314 +Y YK Sbjct: 564 WYDYK 568 Score = 57.4 bits (137), Expect = 8e-09, Method: Composition-based stats. Identities = 38/121 (31%), Positives = 51/121 (42%), Gaps = 7/121 (5%) Query: 185 KTPMTSQKTFESLVDFSKALGKHPVSCKDTPGFIVNRLLVPYLMEAIRLYERGDASK-ED 243 + P +Q+ + +V SK LG D IV RL+ + E R+ E G ASK D Sbjct: 572 RKPYPNQQVNDMIVQHSKDLGITRRKISDEE--IVERLVFALVNEGARILEEGIASKASD 629 Query: 244 IDTAMKLGAGYPM---GPFELLDYVGLDTTKFIVDGWHEMDAENPLHQPSPSLNKLVAEN 300 ID G G+P+ GP D VGL + + Q +P L KL E Sbjct: 630 IDMVYLTGYGFPLFRGGPMLYADQVGLYNVALSMK-RYAKGYHGEAWQVAPLLQKLADEG 688 Query: 301 K 301 K Sbjct: 689 K 689 >2WTB-A nrPDB Length = 725 Score = 296 bits (757), Expect = 1e-80, Method: Composition-based stats. Identities = 99/293 (33%), Positives = 148/293 (50%), Gaps = 10/293 (3%) Query: 21 SAKKIIVKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKK 80 +K V +IGGGLMG+GIA + + V+L + E L ++ +L+ +K Sbjct: 306 GLVPRKIKKVAIIGGGLMGSGIATALILSNYPVILKEVNEKFLEAGIGRVKANLQSRVRK 365 Query: 81 KFAENLKAGDEFVEKTLSTIATSTDAASVVHSTDLVVEAIVENLKVKNELFKRLDKFAAE 140 E EKT+S + S D S D+V+EA++EN+ +K ++F L+K+ + Sbjct: 366 -----GSMSQEKFEKTMSLLKGSLDYESF-RDVDMVIEAVIENISLKQQIFADLEKYCPQ 419 Query: 141 HTIFASNTSSLQITSIANATTRQDRFAGLHFFNPVPVMKLVEVIKTPMTSQKTFESLVDF 200 H I ASNTS++ + I T QDR G HFF+P +M L+E+++T TS + L+D Sbjct: 420 HCILASNTSTIDLNKIGERTKSQDRIVGAHFFSPAHIMPLLEIVRTNHTSAQVIVDLLDV 479 Query: 201 SKALGKHPVSCKDTPGFIVNRLLVPYLMEAIRLYERGDASKEDIDTAMKLGAGYPMGPFE 260 K + K PV + GF VNR+ PY A+ L E G A ID A+ G PMGPF Sbjct: 480 GKKIKKTPVVVGNCTGFAVNRMFFPYTQAAMFLVECG-ADPYLIDRAIS-KFGMPMGPFR 537 Query: 261 LLDYVGLDTTKFIVDGWHEMDAENPLHQPSPSLNKLVAENKFGKKTGEGFYKY 313 L D VG + E +E S + + + + G+ T +GFY Y Sbjct: 538 LCDLVGFGVAIATATQFIENFSERTYK--SMIIPLMQEDKRAGEATRKGFYLY 588 Score = 34.3 bits (77), Expect = 0.077, Method: Composition-based stats. Identities = 20/84 (23%), Positives = 33/84 (39%), Gaps = 6/84 (7%) Query: 223 LVPYLMEAIRLYERGDA-SKEDIDTAMKLGAGYPM---GPFELLDYVGLDTTKFIVDGWH 278 P + EA R++ G A D+D A +G G+P G D +G +D W Sbjct: 632 FFPVVNEACRVFAEGIAVKAADLDIAGIMGMGFPPYRGGIMFWADSIGSKYIYSRLDEWS 691 Query: 279 EMDAENPLHQPSPSLNKLVAENKF 302 + E +P L + ++ Sbjct: 692 KAYGE--FFKPCAFLAERGSKGVL 713 >4OM8-A nrPDB Length = 309 Score = 288 bits (738), Expect = 2e-78, Method: Composition-based stats. Identities = 91/292 (31%), Positives = 149/292 (51%), Gaps = 14/292 (4%) Query: 26 IVKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKKFAEN 85 +++++ +IG G MG G+A A G VV D + +++ S+ VA+ Sbjct: 1 MIRNIAIIGLGTMGPGMAARLARGGLQVVAYDVAPAAIERAR-----SMLSVAETVLD-- 53 Query: 86 LKAGDEFVEKTLSTIATSTDAASVVHSTDLVVEAIVENLKVKNELFKRLDKFAAEHTIFA 145 G + T+ + D V DLV+E + EN+ +K ++++ +D + TI A Sbjct: 54 -ALGIALPSAGVGTVRFTDDIGDAVSGADLVIENVPENISIKADVYRTIDGLIGQDTIVA 112 Query: 146 SNTSSLQITSIANATTRQDRFAGLHFFNPVPVMKLVEVIKTPMTSQKTFESLVDFSKALG 205 S+TS + IT + + +R G+H+ NP ++ ++EVI T+ +T ++ D +++G Sbjct: 113 SDTSGIPITKLQAHISYPERMVGMHWSNPPHIIPMIEVIAGEKTAPQTVATIRDLIRSIG 172 Query: 206 KHPVSC-KDTPGFIVNRLLVPYLMEAIRLYERGDASKEDIDTAMKLGAGYP---MGPFEL 261 PV KD PGF+ NR+L L EA+ L ERG ED+DT + G GY +GP L Sbjct: 173 LLPVVVKKDVPGFVENRVLYALLREAVDLVERGVIDPEDLDTCVSWGIGYKIAVIGPMAL 232 Query: 262 LDYVGLDTTKFIVDGWHEMDAENPLHQPSPSLNKLVAENKFGKKTGEGFYKY 313 LD GLD K + D N +P + + + +KFG K+GEG + Y Sbjct: 233 LDMAGLDIYKSVSSFL-NADLSN-RDDVAPMVLEKTSASKFGIKSGEGMFCY 282 >4DYD-A nrPDB Length = 283 Score = 285 bits (730), Expect = 1e-77, Method: Composition-based stats. Identities = 106/292 (36%), Positives = 153/292 (52%), Gaps = 13/292 (4%) Query: 25 IIVKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKKFAE 84 + +VTV+G G++G+ IA A G V D D L +KK E L V +K+ A Sbjct: 2 TGITNVTVLGTGVLGSQIAFQTAFHGFAVTAYDINTDALDAAKKRF-EGLAAVYEKEVAG 60 Query: 85 NLKAGDEFVEKTLSTIATSTDAASVVHSTDLVVEAIVENLKVKNELFKRLDKFAAEHTIF 144 A D +K L I S D A V DLV+EA+ E+L +K +++ +L + A TIF Sbjct: 61 ---AADGAAQKALGGIRYSDDLAQAVKDADLVIEAVPESLDLKRDIYTKLGELAPAKTIF 117 Query: 145 ASNTSSLQITSIANATTRQDRFAGLHFFNPVPVMKLVEVIKTPMTSQKTFESLVDFSKAL 204 A+N+S+L + + T R D+F LHF N V V EV+ T T + ++ +V+F+ A+ Sbjct: 118 ATNSSTLLPSDLVGYTGRGDKFLALHFANHVWVNNTAEVMGTTKTDPEVYQQVVEFASAI 177 Query: 205 GKHPVSC-KDTPGFIVNRLLVPYLMEAIRLYERGDASKEDIDTAMKLGAGYPMGPFELLD 263 G P+ K+ G+++N LLVP L A L G A E ID ++G G P GPFE+ D Sbjct: 178 GMVPIELKKEKAGYVLNSLLVPLLDAAAELLVDGIADPETIDKTWRIGTGAPKGPFEIFD 237 Query: 264 YVGLDTTKFI--VDGWHEMDAENPLHQPSPSLNKLVAENKFGKKTGEGFYKY 313 VGL T I V G + + L + + + K G TGEGFY+Y Sbjct: 238 IVGLTTAYNISSVSGPKQREFAAYLKE------NYIDKGKLGLATGEGFYRY 283 >3K6J-A nrPDB Length = 460 Score = 285 bits (728), Expect = 2e-77, Method: Composition-based stats. Identities = 87/288 (30%), Positives = 145/288 (50%), Gaps = 20/288 (6%) Query: 27 VKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKKFAENL 86 V V +IGGG MG +A G LV + E + K+ +E + +K F Sbjct: 54 VNSVAIIGGGTMGKAMAICFGLAGIETFLVVRNEQ---RCKQELE--VMYAREKSFK--- 105 Query: 87 KAGDEFVEKTLSTIATSTDAASVVHSTDLVVEAIVENLKVKNELFKRLDKFAAEHTIFAS 146 + D+ +EK + + ++D + + DL+VE+++E++K+K ELF L+ IF + Sbjct: 106 RLNDKRIEKINANLKITSDFHKL-SNCDLIVESVIEDMKLKKELFANLENICKSTCIFGT 164 Query: 147 NTSSLQITSIANATTRQDRFAGLHFFNPVPVMKLVEVIKTPMTSQKTFESLVDFSKALGK 206 NTSSL + I++ G+HFFNP V++LVE+I TS + + +++ K Sbjct: 165 NTSSLDLNEISSVLRDPSNLVGIHFFNPANVIRLVEIIYGSHTSSQAIATAFQACESIKK 224 Query: 207 HPVSCKDTPGFIVNRLLVPYLMEAIR-LYERGDASKEDIDTAMKLGAGYPMGPFELLDYV 265 PV + F+ NRLL Y ++ + +YE G ID + G+ MGP + D Sbjct: 225 LPVLVGNCKSFVFNRLLHVYFDQSQKLMYEYGYL-PHQIDKIIT-NFGFLMGPMTVADMN 282 Query: 266 GLDTTKFIVDGWHEMDAENPLHQPSPSLNKLVAENKFGKKTGEGFYKY 313 G D + ++ EN L +P+P ++ ++G+KT +GFYKY Sbjct: 283 GFDVME-------KLKKENGL-EPNPIEKEMWRLKRYGRKTNKGFYKY 322 Score = 50.1 bits (118), Expect = 1e-06, Method: Composition-based stats. Identities = 22/81 (27%), Positives = 36/81 (44%), Gaps = 4/81 (4%) Query: 218 IVNRLLVPYLMEAIRLYERGDASKED-IDTAMKLGAGYPM---GPFELLDYVGLDTTKFI 273 ++N +L P + E R E G S E ID LG G+P+ GP GLD + Sbjct: 358 VINFMLYPTVNEGYRCIEEGVISNESLIDIMFILGFGWPIHSGGPMRFGKTEGLDKIANM 417 Query: 274 VDGWHEMDAENPLHQPSPSLN 294 + W ++ + + + +L Sbjct: 418 LVHWSSLEPKESAYIVADALK 438 >2D3T-A nrPDB Length = 715 Score = 269 bits (688), Expect = 9e-73, Method: Composition-based stats. Identities = 97/288 (33%), Positives = 147/288 (51%), Gaps = 8/288 (2%) Query: 27 VKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKKFAENL 86 VK V+G G+MG GIA +A+ G +++ D E + + + L K Sbjct: 314 VKQAAVLGAGIMGGGIAYQSASKGTPILMKDINEHGIEQGLAEAAKLLVGRVDK-----G 368 Query: 87 KAGDEFVEKTLSTIATSTDAASVVHSTDLVVEAIVENLKVKNELFKRLDKFAAEHTIFAS 146 + + + L+ I + + DLVVEA+VEN KVK + ++ E I AS Sbjct: 369 RMTPAKMAEVLNGIRPTLSYGDF-GNVDLVVEAVVENPKVKQAVLAEVENHVREDAILAS 427 Query: 147 NTSSLQITSIANATTRQDRFAGLHFFNPVPVMKLVEVIKTPMTSQKTFESLVDFSKALGK 206 NTS++ I+ +A A R + F G+HFFNPV +M LVEVI+ +S + V ++K +GK Sbjct: 428 NTSTISISLLAKALKRPENFVGMHFFNPVHMMPLVEVIRGEKSSDLAVATTVAYAKKMGK 487 Query: 207 HPVSCKDTPGFIVNRLLVPYLMEAIRLYERGDASKEDIDTAMKLGAGYPMGPFELLDYVG 266 +P+ D PGF+VNR+L PY +L G ID M+ G+PMGP L+D VG Sbjct: 488 NPIVVNDCPGFLVNRVLFPYFGGFAKLVSAGV-DFVRIDKVME-KFGWPMGPAYLMDVVG 545 Query: 267 LDTTKFIVDGWHEMDAENPLHQPSPSLNKLVAENKFGKKTGEGFYKYK 314 +DT D E + +++ L + G+K G+GFY Y+ Sbjct: 546 IDTGHHGRDVMAEGFPDRMKDDRRSAIDALYEAKRLGQKNGKGFYAYE 593 Score = 37.0 bits (84), Expect = 0.012, Method: Composition-based stats. Identities = 20/88 (22%), Positives = 42/88 (47%), Gaps = 7/88 (7%) Query: 218 IVNRLLVPYLMEAIRLYERGDA-SKEDIDTAMKLGAGYPM---GPFELLDYVGLDTTKFI 273 I+N +++P +E +R E G + + D + G G+P+ G +D +G+ + Sbjct: 627 IINWMMIPLCLETVRCLEDGIVETAAEADMGLVYGIGFPLFRGGALRYIDSIGVAEFVAL 686 Query: 274 VDGWHEMDAENPLHQPSPSLNKLVAENK 301 D + E+ A L+ P+ L ++ + Sbjct: 687 ADQYAELGA---LYHPTAKLREMAKNGQ 711 >1ZEJ-A nrPDB Length = 293 Score = 264 bits (675), Expect = 3e-71, Method: Composition-based stats. Identities = 92/288 (31%), Positives = 132/288 (45%), Gaps = 33/288 (11%) Query: 29 HVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKKFAENLKA 88 V VIG GLMG GIA A+ H VVL D +E L +++ I E L Sbjct: 14 KVFVIGAGLMGRGIAIAIASK-HEVVLQDVSEKALEAAREQIPEEL-------------- 58 Query: 89 GDEFVEKTLSTIATSTDAASVVHSTDLVVEAIVENLKVKNELFKRLDKFAAEHTIFASNT 148 LS I +T V D+V+EA+ E+L K E+ + +++ + SNT Sbjct: 59 --------LSKIEFTTTLEK-VKDCDIVMEAVFEDLNTKVEVLREVERLT--NAPLCSNT 107 Query: 149 SSLQITSIANATTRQDRFAGLHFFNPVPVMKLVEVIKTPMTSQKTFESLVDFSKALGKHP 208 S + + IA RF G+H+ NP VM LVE++ + T KT + F + LGK Sbjct: 108 SVISVDDIAERLDSPSRFLGVHWMNPPHVMPLVEIVISRFTDSKTVAFVEGFLRELGKEV 167 Query: 209 VSCKDTPGFIVNRLLVPYLMEAIRLYERGDASKEDIDTAMKLGAGY---PMGPFELLDYV 265 V CK +VNR L EA R+ E G ED+D K G GP LDY+ Sbjct: 168 VVCKGQS--LVNRFNAAVLSEASRMIEEGV-RAEDVDRVWKHHLGLLYTLFGPLGNLDYI 224 Query: 266 GLDTTKFIVDGWHEMDAENPLHQPSPSLNKLVAENKFGKKTGEGFYKY 313 GLD + ++ + +P L + + + + G K G+G Y+Y Sbjct: 225 GLDVAYYASLYLYKRFGDEK-FKPPEWLQEKIKKGEVGVKAGKGIYEY 271 >3F3S-A nrPDB Length = 313 Score = 258 bits (658), Expect = 3e-69, Method: Composition-based stats. Identities = 67/275 (24%), Positives = 118/275 (42%), Gaps = 8/275 (2%) Query: 30 VTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKKFAENLKAG 89 V ++G G++G A + A+ G V L D + + + + I + ++ + + G Sbjct: 6 VVIVGSGVIGRSWAMLFASGGFQVKLYDIEQQQIRNALENIRKEMKLLEQ----AGSLKG 61 Query: 90 DEFVEKTLSTIATSTDAASVVHSTDLVVEAIVENLKVKNELFKRLDKFAAEHTIFASNTS 149 VE+ LS I+ + V + E + E+L++K ++F +LD + I +S+TS Sbjct: 62 SLSVEEQLSLISGCPNIQEAVEGAMHIQECVPEDLELKKKIFAQLDSIIDDRVILSSSTS 121 Query: 150 SLQITSIANATTRQDRFAGLHFFNPVPVMKLVEVIKTPMTSQKTFESLVDFSKALGKHPV 209 L + + + H NP + LVE++ P T+ T + K +G+ P+ Sbjct: 122 CLMPSKLFAGLVHVKQCIVAHPVNPPYYIPLVELVPHPETAPTTVDRTHALMKKIGQCPM 181 Query: 210 SC-KDTPGFIVNRLLVPYLMEAIRLYERGDASKEDIDTAMKLGAGYP---MGPFELLDYV 265 K+ GF++NRL + EA RL E G S D+D M G G +GP E + Sbjct: 182 RVQKEVAGFVLNRLQYAIISEAWRLVEEGIVSPSDLDLVMSEGLGMRYAFIGPLETMHLN 241 Query: 266 GLDTTKFIVDGWHEMDAENPLHQPSPSLNKLVAEN 300 + + P P ++ AE Sbjct: 242 AEGMLSYCDRYSEGIKHVLQTFGPIPEFSRATAEK 276 >3ADO-A nrPDB Length = 319 Score = 233 bits (593), Expect = 1e-61, Method: Composition-based stats. Identities = 66/237 (27%), Positives = 108/237 (45%), Gaps = 8/237 (3%) Query: 30 VTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKKFAENLKAG 89 V ++G GL+G A + A+ G V L D + + + I + + K G Sbjct: 9 VLIVGSGLVGRSWAMLFASGGFRVKLYDIEPRQITGALENIRKEM----KSLQQSGSLKG 64 Query: 90 DEFVEKTLSTIATSTDAASVVHSTDLVVEAIVENLKVKNELFKRLDKFAAEHTIFASNTS 149 E+ LS I++ T+ A V + E + ENL +K ++F +LD + + +S++S Sbjct: 65 SLSAEEQLSLISSCTNLAEAVEGVVHIQECVPENLDLKRKIFAQLDSIVDDRVVLSSSSS 124 Query: 150 SLQITSIANATTRQDRFAGLHFFNPVPVMKLVEVIKTPMTSQKTFESLVDFSKALGKHPV 209 L + + + H NP + LVE++ P TS T + + +G+ PV Sbjct: 125 CLLPSKLFTGLAHVKQCIVAHPVNPPYYIPLVELVPHPETSPATVDRTHALMRKIGQSPV 184 Query: 210 SC-KDTPGFIVNRLLVPYLMEAIRLYERGDASKEDIDTAMKLGAGYP---MGPFELL 262 K+ GF++NRL + EA RL E G S D+D M G G +GP E + Sbjct: 185 RVLKEIDGFVLNRLQYAIISEAWRLVEEGIVSPSDLDLVMSDGLGMRYAFIGPLETM 241 >3CTV-A nrPDB Length = 110 Score = 59.0 bits (141), Expect = 3e-09, Method: Composition-based stats. Identities = 28/83 (33%), Positives = 44/83 (53%), Gaps = 3/83 (3%) Query: 227 LMEAIRLYERGDASKEDIDTAMKLGAGYPMGPFELLDYVGLDTTKFIVDGWHEMDAENPL 286 + EA++L E G A+ +DIDTA+KLG P GPFEL G + ++ + + + Sbjct: 28 INEAVKLVEMGVATPQDIDTAIKLGLNRPFGPFELAKQFGAEQIAKRLEELAKQFGK-KI 86 Query: 287 HQPSPSLNK--LVAENKFGKKTG 307 +P+ +L + L K GK G Sbjct: 87 FEPAKTLKEGKLEELLKAGKAEG 109 >2BC1-A nrPDB Length = 490 Score = 47.8 bits (112), Expect = 7e-06, Method: Composition-based stats. Identities = 25/114 (21%), Positives = 45/114 (39%) Query: 7 QFMRSVSSSSTASASAKKIIVKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKS 66 QF++ +S+ A + +K V V+G G +G +A+ G VVL+D + LA Sbjct: 174 QFVKLYQNSADVIAKLENKDIKRVAVVGAGYIGVELAEAFQRKGKEVVLIDVVDTCLAGY 233 Query: 67 KKGIEESLRKVAKKKFAENLKAGDEFVEKTLSTIATSTDAASVVHSTDLVVEAI 120 L ++ L G+ E + + D+V+ A+ Sbjct: 234 YDRDLTDLMAKNMEEHGIQLAFGETVKEVAGNGKVEKIITDKNEYDVDMVILAV 287 >3PLN-A nrPDB Length = 424 Score = 43.9 bits (102), Expect = 8e-05, Method: Composition-based stats. Identities = 24/132 (18%), Positives = 44/132 (33%), Gaps = 19/132 (14%) Query: 29 HVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKKFAENLKA 88 +T+ G G +G V A H VV +D + + + I + K ++ AE Sbjct: 38 KITISGTGYVGLS-NGVLIAQNHEVVALDIVQAKVDMLNQKISPIVDKEIQEYLAEKPL- 95 Query: 89 GDEFVEKTLSTIATSTDAASVVHSTDLVVEAIVENLKVKNELF--KRLDKFAAEHTIFAS 146 +TD + D V+ A + K F ++ + T Sbjct: 96 ----------NFRATTDKHDAYRNADYVIIATPTDYDPKTNYFNTSTVEAVIRDVTEINP 145 Query: 147 NT-----SSLQI 153 N S++ + Sbjct: 146 NAVMIIKSTIPV 157 >4R16-A nrPDB Length = 418 Score = 43.6 bits (101), Expect = 1e-04, Method: Composition-based stats. Identities = 17/76 (22%), Positives = 33/76 (43%) Query: 29 HVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKKFAENLKA 88 + V+G G +G A + A++G+ VV D +++ K G+ + ++ E L Sbjct: 2 RIAVLGLGYIGLPTAIMFASSGYDVVGYDIRSEVIKKINSGVAHIIEPEIDRRLKEVLSL 61 Query: 89 GDEFVEKTLSTIATST 104 G V + + S Sbjct: 62 GKLKVTDRVEDLKGSN 77 >1MV8-A nrPDB Length = 436 Score = 42.0 bits (97), Expect = 3e-04, Method: Composition-based stats. Identities = 18/92 (19%), Positives = 33/92 (35%), Gaps = 9/92 (9%) Query: 29 HVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKKFAENLKA 88 +++ G G +GA A +A GH V+ VD + + L K E Sbjct: 2 RISIFGLGYVGAVCAGCLSARGHEVIGVDVSSTKID---------LINQGKSPIVEPGLE 52 Query: 89 GDEFVEKTLSTIATSTDAASVVHSTDLVVEAI 120 + ++ +TD V +D+ + Sbjct: 53 ALLQQGRQTGRLSGTTDFKKAVLDSDVSFICV 84 >2GF2-A nrPDB Length = 296 Score = 42.0 bits (97), Expect = 3e-04, Method: Composition-based stats. Identities = 22/111 (19%), Positives = 44/111 (39%), Gaps = 5/111 (4%) Query: 30 VTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDI---LAKSKKGIEESLRKVAKKKFAENL 86 V IG G MG +A+ G+ +++ D D + + + S VA+K A+ + Sbjct: 3 VGFIGLGNMGNPMAKNLMKHGYPLIIYDVFPDACKEFQDAGEQVVSSPADVAEK--ADRI 60 Query: 87 KAGDEFVEKTLSTIATSTDAASVVHSTDLVVEAIVENLKVKNELFKRLDKF 137 + + + V L++++ + V EL K ++K Sbjct: 61 ITMLPTSINAIEAYSGANGILKKVKKGSLLIDSSTIDPAVSKELAKEVEKM 111 >4WJI-A nrPDB Length = 293 Score = 41.6 bits (96), Expect = 4e-04, Method: Composition-based stats. Identities = 31/166 (18%), Positives = 49/166 (29%), Gaps = 36/166 (21%) Query: 28 KHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKKFAENLK 87 + + +IG GL+G+ IA D E LA I + R A K A L Sbjct: 5 QTIALIGIGLIGSSIA------------RDIREKQLA---GTIVVTTRSEATLKRAGELG 49 Query: 88 AGDEFVEKTLSTIATSTDAASVVHSTDLVVEAIVENLKVKNELFKRLDKFAAEHTIFASN 147 GD + AA V DLVV ++ + + + I Sbjct: 50 LGD----------RYTLSAAEAVEGADLVVVSVP--VGASGAVAAEIAAHLKPGAI---- 93 Query: 148 TSSLQITSIANATTRQDRFAGLHFFNPVPVMKLVEVIKTPMTSQKT 193 +T + + H V + + T + Sbjct: 94 -----VTDVGSTKGSVIAQMAPHLPKDVHFVPGHPIAGTEHSGPDA 134 >4A7P-A nrPDB Length = 446 Score = 41.6 bits (96), Expect = 4e-04, Method: Composition-based stats. Identities = 18/92 (19%), Positives = 38/92 (41%), Gaps = 9/92 (9%) Query: 29 HVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKKFAENLKA 88 + +IG G +G + GH VV VD+ A+ + + +++ + + + + Sbjct: 10 RIAMIGTGYVGLVSGACFSDFGHEVVCVDKD----ARKIELLHQNVMPIYEPGLDALVAS 65 Query: 89 GDEFVEKTLSTIATSTDAASVVHSTDLVVEAI 120 + ++ +TD A V D V A+ Sbjct: 66 NVKA-----GRLSFTTDLAEGVKDADAVFIAV 92 >5U8W-A nrPDB Length = 481 Score = 41.3 bits (95), Expect = 5e-04, Method: Composition-based stats. Identities = 20/96 (20%), Positives = 40/96 (41%), Gaps = 3/96 (3%) Query: 28 KHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKKFAE--- 84 K + VIG G++G + V A G V +++ + L + + I + KV K+ Sbjct: 185 KKLGVIGAGVIGLELGSVWARLGAEVTVLEALDKFLPAADEQIAKEALKVLTKQGLNIRL 244 Query: 85 NLKAGDEFVEKTLSTIATSTDAASVVHSTDLVVEAI 120 + V+K T+ + + D ++ A+ Sbjct: 245 GARVTASEVKKKQVTVTFTDANGEQKETFDKLIVAV 280 >5ER0-A nrPDB Length = 518 Score = 41.3 bits (95), Expect = 6e-04, Method: Composition-based stats. Identities = 35/157 (22%), Positives = 55/157 (35%), Gaps = 10/157 (6%) Query: 28 KHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKKFAENLK 87 K +TVIG G +GA +A+ + TGH V L+D ++ K + + + L Sbjct: 198 KRITVIGAGYIGAELAEAYSTTGHDVTLIDAMARVMPKYFDADFTDVIEQDYRDHGVQLA 257 Query: 88 AGDEFVEKTLSTIATSTDAASVVHSTDLVVEAIVENLKVKNELFKRLDKFAAEHTIFASN 147 G+ T S + + TDL + I +L K A I + Sbjct: 258 LGETVESFTDSATGLTIKTDKNSYETDLAILCIGFRPNT--DLLKGKVDMAPNGAIITDD 315 Query: 148 TSSLQITSIANATTRQDRFAGLHFFNPVP---VMKLV 181 I A A +H+ NP + L Sbjct: 316 YMRSSNPDIFAAGDS----AAVHY-NPTHQNAYIPLA 347 >3OJO-A nrPDB Length = 431 Score = 40.9 bits (94), Expect = 7e-04, Method: Composition-based stats. Identities = 22/105 (20%), Positives = 39/105 (37%), Gaps = 18/105 (17%) Query: 28 KHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAK-----------SKKGIEESLRK 76 +TV+G G +G + + A G V+ VD + + K + + E + Sbjct: 12 SKLTVVGLGYIGLPTSIMFAKHGVDVLGVDINQQTIDKLQNGQISIEEPGLQEVYEEVLS 71 Query: 77 VAKKKFAENLKAGDEFVEKTLSTIATSTDAASVVHSTD--LVVEA 119 K K + +A D F+ + + S D LV+ A Sbjct: 72 SGKLKVSTTPEASDVFIIAV-----PTPNNDDQYRSCDISLVMRA 111 >3KVE-A nrPDB Length = 486 Score = 39.7 bits (91), Expect = 0.002, Method: Composition-based stats. Identities = 14/41 (34%), Positives = 22/41 (53%) Query: 28 KHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKK 68 KHV V+G G+ G A V A GH V +++ +E + + Sbjct: 34 KHVVVVGAGMSGLSAAYVLAGAGHKVTVLEASERAGGRVRT 74 >5X6R-A nrPDB Length = 420 Score = 39.3 bits (90), Expect = 0.002, Method: Composition-based stats. Identities = 18/70 (25%), Positives = 32/70 (45%), Gaps = 1/70 (1%) Query: 23 KKIIVKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTED-ILAKSKKGIEESLRKVAKKK 81 + + + V +IG GL+G A + G+ V L D +D L +K +S+ + Sbjct: 24 QGSMSESVAIIGAGLVGCLAALAFSKEGYNVTLYDFRQDPRLDTTKNKNLKSINLAISAR 83 Query: 82 FAENLKAGDE 91 + LK+ D Sbjct: 84 GIDALKSIDP 93 >4D3F-A nrPDB Length = 310 Score = 38.6 bits (88), Expect = 0.004, Method: Composition-based stats. Identities = 27/115 (23%), Positives = 42/115 (36%), Gaps = 18/115 (15%) Query: 28 KHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKKFAENLK 87 K VTVIG G MG +A V G++V + ++T + + V + A L Sbjct: 22 KSVTVIGLGPMGQAMADVFLEYGYSVTVWNRTSSKADQLVAKGAIRVSTVNEALAANEL- 80 Query: 88 AGDEFVEKTLSTIATSTDAASVVHSTDLVVEAIVENLKVKNELFKRLDKFAAEHT 142 I + TD + ++E + ENL K + L E Sbjct: 81 -----------VILSLTDYNVMYS----ILEPVSENLFGK--VLVNLSSDTPEKA 118 >1REO-A nrPDB Length = 486 Score = 38.6 bits (88), Expect = 0.004, Method: Composition-based stats. Identities = 13/41 (31%), Positives = 22/41 (53%) Query: 28 KHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKK 68 KHV V+G G+ G A V + GH V +++ +E + + Sbjct: 34 KHVVVVGAGMSGLSAAYVLSGAGHQVTVLEASERAGGRVRT 74 >1F8S-A nrPDB Length = 498 Score = 38.6 bits (88), Expect = 0.004, Method: Composition-based stats. Identities = 13/41 (31%), Positives = 22/41 (53%) Query: 28 KHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKK 68 KHV ++G G+ G A V A GH V +++ +E + + Sbjct: 34 KHVVIVGAGMAGLSAAYVLAGAGHQVTVLEASERPGGRVRT 74 >6ABJ-A nrPDB Length = 345 Score = 37.4 bits (85), Expect = 0.008, Method: Composition-based stats. Identities = 28/152 (18%), Positives = 51/152 (33%), Gaps = 10/152 (6%) Query: 28 KHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTE----DILAKSKKGIEESLRKVAKKKFA 83 K V VIG G +G A++ A G ++ D L + ++L + Sbjct: 161 KRVGVIGTGQIGETFARIMAGFGCELLAYDPYPNPRIQALG-GRYLALDALLAESDIVSL 219 Query: 84 ENLKAGDEF---VEKTLSTIATSTDAASVVHSTDLVVEAIVENLKVKNELFKRLDKFAAE 140 D + L+T+ + + A++E LK + LD + E Sbjct: 220 HCPLTADTRHLIDAQRLATMKPGAMLINTGRGALVNAAALIEALKSGQLGYLGLDVYEEE 279 Query: 141 HTIFASNTSSLQITS--IANATTRQDRFAGLH 170 IF + S + +A + + H Sbjct: 280 ADIFFEDRSDQPLQDDVLARLLSFPNVVVTAH 311 >3X2F-A nrPDB Length = 411 Score = 37.4 bits (85), Expect = 0.009, Method: Composition-based stats. Identities = 23/106 (21%), Positives = 40/106 (37%), Gaps = 6/106 (5%) Query: 28 KHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTE-DILAKSKKGIE----ESLRKVAKKKF 82 K+V V G G G GIA AA G V++ + + G + K+A Sbjct: 198 KNVVVAGYGWCGRGIALRAAGLGARVIVTEVDPVKAVEAIMDGFTVMPMKEAVKIADFVI 257 Query: 83 AENLKAGDEFVEKTLSTIATSTDAASVVHSTDLVVEAIVENLKVKN 128 + E LS + A + + ++ V ++E + V+ Sbjct: 258 TASGNTDVLSKEDILSLKDGAVLANAGHFNVEIPVR-VLEEIAVEK 302 >3GGO-A nrPDB Length = 314 Score = 37.4 bits (85), Expect = 0.009, Method: Composition-based stats. Identities = 21/123 (17%), Positives = 44/123 (35%), Gaps = 10/123 (8%) Query: 23 KKIIVKHVTVIGGGLMGAGIAQVAAATGHTVVL--VDQTEDILAKSKK--GIEESLRKVA 78 K + +++V ++G G MG A+ +G + D + ++K+ I+E +A Sbjct: 29 KSLSMQNVLIVGVGFMGGSFAKSLRRSGFKGKIYGYDINPESISKAVDLGIIDEGTTSIA 88 Query: 79 KKKFAENLKAGDEFVEKTLSTIATSTDAASVVHSTDLVVEAIVENLKVKNELFKRLDKFA 138 K + +T IA + + + VK +L L+ Sbjct: 89 KVEDFSPDFVMLSSPVRTFREIAKKLSYI-LSEDA-----TVTDQGSVKGKLVYDLENIL 142 Query: 139 AEH 141 + Sbjct: 143 GKR 145 >6AON-A nrPDB Length = 478 Score = 37.0 bits (84), Expect = 0.009, Method: Composition-based stats. Identities = 15/75 (20%), Positives = 32/75 (42%), Gaps = 1/75 (1%) Query: 28 KHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEES-LRKVAKKKFAENL 86 K + VIG G++G + V G V +++ + LA + + + + L+ AK+ Sbjct: 187 KKLGVIGAGVIGLEMGSVWRRLGAEVTILEAMPEFLAAADQQVAKEALKSFAKQGLDIQT 246 Query: 87 KAGDEFVEKTLSTIA 101 ++ +I Sbjct: 247 GVKIGEIKAAAKSIT 261 >5JE8-A nrPDB Length = 302 Score = 37.0 bits (84), Expect = 0.010, Method: Composition-based stats. Identities = 17/63 (26%), Positives = 30/63 (47%), Gaps = 3/63 (4%) Query: 21 SAKKIIVKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDI---LAKSKKGIEESLRKV 77 + K +K + IG G MG +++ +G+TV VD ++ K I S+ K+ Sbjct: 1 GSAKDPMKKIGFIGLGNMGLPMSKNLVKSGYTVYGVDLNKEAEASFEKEGGIIGLSISKL 60 Query: 78 AKK 80 A+ Sbjct: 61 AET 63 >4XRR-A nrPDB Length = 456 Score = 37.0 bits (84), Expect = 0.011, Method: Composition-based stats. Identities = 22/102 (21%), Positives = 36/102 (35%), Gaps = 11/102 (10%) Query: 19 SASAKKIIVKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVA 78 + +K V + G G +G +A A G VV VD +A + G Sbjct: 8 PDPGEPSPLK-VVIAGAGYVGTCLAVTLAGRGAEVVAVDSDPGTVADLRAG--------- 57 Query: 79 KKKFAENLKAGDEFVEKTLSTIATSTDAASVVHSTDLVVEAI 120 + + E AG + ST V + D+V+ + Sbjct: 58 RCRLPEPGLAGAVRDLAATGRLTASTSY-DPVGAADVVIVTV 98 >1PS9-A nrPDB Length = 671 Score = 36.6 bits (83), Expect = 0.013, Method: Composition-based stats. Identities = 23/74 (31%), Positives = 35/74 (47%), Gaps = 4/74 (5%) Query: 28 KHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKKFAENLK 87 K++ V+G G G A AAA GH V L D +I + I + + K++F E L+ Sbjct: 374 KNLAVVGAGPAGLAFAINAAARGHQVTLFDAHSEI--GGQFNIAKQIP--GKEEFYETLR 429 Query: 88 AGDEFVEKTLSTIA 101 +E T T+ Sbjct: 430 YYRRMIEVTGVTLK 443 >3G5Q-A nrPDB Length = 443 Score = 36.6 bits (83), Expect = 0.013, Method: Composition-based stats. Identities = 36/158 (22%), Positives = 56/158 (35%), Gaps = 18/158 (11%) Query: 27 VKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDIL--AKSKKGIEESLRKVAKKKFAE 84 ++ V V+G GL G+ A G V L + + A E + + E Sbjct: 1 MERVNVVGAGLAGSEAAWTLLRLGVPVRLFEMRPKRMTPAHGTDRFAEIVCSNSLGGEGE 60 Query: 85 NLKAGDEFVE--KTLSTIATSTDAASVVHSTDLVVEA------IVENLK---VKNELFKR 133 G E + S + + D A V L V+ I E L + + + Sbjct: 61 TNAKGLLQAEMRRAGSLVMEAADLARVPAGGALAVDREEFSGYITERLTGHPLLEVVREE 120 Query: 134 LDKFAAEHTIFASNTSSLQITSIANATTRQDRFAGLHF 171 + + T+ A T L ++A A R RF G HF Sbjct: 121 VREIPPGITVLA--TGPLTSEALAEALKR--RF-GDHF 153 >3H2Z-A nrPDB Length = 382 Score = 36.6 bits (83), Expect = 0.013, Method: Composition-based stats. Identities = 16/88 (18%), Positives = 31/88 (35%), Gaps = 8/88 (9%) Query: 34 GGGLMGAG-IAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKKFAENLKAGDEF 92 G G +G G I ++ A G + D + +L + V + + + Sbjct: 7 GAGNIGRGFIGKLLADAGIQLTFADVNQVVLDALNARHSYQVHVVGETEQV-------DT 59 Query: 93 VEKTLSTIATSTDAASVVHSTDLVVEAI 120 V + + D ++ DLV A+ Sbjct: 60 VSGVNAVSSIGDDVVDLIAQVDLVTTAV 87 >4OQZ-A nrPDB Length = 289 Score = 36.6 bits (83), Expect = 0.013, Method: Composition-based stats. Identities = 13/38 (34%), Positives = 18/38 (47%) Query: 28 KHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAK 65 + VTVIG G MG +A G+ V L ++T Sbjct: 3 QSVTVIGLGPMGQAMAAAYLDRGYEVTLWNRTASRADA 40 >2G5C-A nrPDB Length = 281 Score = 36.6 bits (83), Expect = 0.014, Method: Composition-based stats. Identities = 20/119 (16%), Positives = 42/119 (35%), Gaps = 10/119 (8%) Query: 27 VKHVTVIGGGLMGAGIAQVAAATGHTVVL--VDQTEDILAKSKK--GIEESLRKVAKKKF 82 +++V ++G G MG A+ +G + D + ++K+ I+E +AK + Sbjct: 1 MQNVLIVGVGFMGGSFAKSLRRSGFKGKIYGYDINPESISKAVDLGIIDEGTTSIAKVED 60 Query: 83 AENLKAGDEFVEKTLSTIATSTDAASVVHSTDLVVEAIVENLKVKNELFKRLDKFAAEH 141 +T IA + + + VK +L L+ + Sbjct: 61 FSPDFVMLSSPVRTFREIAKKLSYI-LSEDA-----TVTDQGSVKGKLVYDLENILGKR 113 >1VPD-A nrPDB Length = 299 Score = 36.6 bits (83), Expect = 0.015, Method: Composition-based stats. Identities = 18/92 (19%), Positives = 37/92 (40%), Gaps = 9/92 (9%) Query: 29 HVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKKFAENLKA 88 V IG G+MG +++ G+++V+ D+ + +A A + A KA Sbjct: 7 KVGFIGLGIMGKPMSKNLLKAGYSLVVSDRNPEAIADVIA---------AGAETASTAKA 57 Query: 89 GDEFVEKTLSTIATSTDAASVVHSTDLVVEAI 120 E + ++ + S V + ++E Sbjct: 58 IAEQCDVIITMLPNSPHVKEVALGENGIIEGA 89 >6BZ0-A nrPDB Length = 480 Score = 36.6 bits (83), Expect = 0.015, Method: Composition-based stats. Identities = 15/100 (15%), Positives = 37/100 (37%), Gaps = 3/100 (3%) Query: 24 KIIVKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKKFA 83 + K + VIG G++G + V G VV+ + + L + K + + +K+ K+ Sbjct: 180 PEVPKRLGVIGAGVIGLELGSVWRRLGAEVVVFEAMDAFLPMADKALSKEYQKILTKQGL 239 Query: 84 ENLKAGDEFVEKTLST---IATSTDAASVVHSTDLVVEAI 120 + + + + + D ++ + Sbjct: 240 DIRIGAKVSGTEVNGREVTVKYTQAGEDKEQTFDKLIVCV 279 >3VTF-A nrPDB Length = 444 Score = 36.2 bits (82), Expect = 0.016, Method: Composition-based stats. Identities = 18/80 (22%), Positives = 32/80 (40%) Query: 27 VKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKKFAENL 86 + ++V+G G +G A A GH VV D I+ + + G ++ L Sbjct: 21 MASLSVLGLGYVGVVHAVGFALLGHRVVGYDVNPSIVERLRAGRPHIYEPGLEEALGRAL 80 Query: 87 KAGDEFVEKTLSTIATSTDA 106 +G ++ +TDA Sbjct: 81 SSGRLSFAESAEEAVAATDA 100 >3FG2-P nrPDB Length = 404 Score = 36.2 bits (82), Expect = 0.019, Method: Composition-based stats. Identities = 22/95 (23%), Positives = 32/95 (33%), Gaps = 2/95 (2%) Query: 28 KHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKKFAENLK 87 KHV VIG G +G A A A G V +V+ ++A+ S + Sbjct: 143 KHVVVIGAGFIGLEFAATARAKGLEVDVVELAPRVMARVVTPEISSYFHDRHSGAGIRMH 202 Query: 88 AGDEFVEKTLS--TIATSTDAASVVHSTDLVVEAI 120 G E + + DLVV + Sbjct: 203 YGVRATEIAAEGDRVTGVVLSDGNTLPCDLVVVGV 237 >2VHY-A nrPDB Length = 377 Score = 36.2 bits (82), Expect = 0.021, Method: Composition-based stats. Identities = 23/114 (20%), Positives = 38/114 (33%), Gaps = 22/114 (19%) Query: 7 QFMRSVSSSSTASASAKKIIVKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKS 66 MR+ + V VIG G G A++A G TV ++D D L Sbjct: 148 HLMRTQGGRGVLMGGVPGVEPADVVVIGAGTAGYNAARIANGMGATVTVLDINIDKLR-- 205 Query: 67 KKGIEESLRKVAKKKFAENLKAGDEFVEKTLSTIATSTDAASVVHSTDLVVEAI 120 + EF + + +++ + V DLV+ A+ Sbjct: 206 --------------------QLDAEFCGRIHTRYSSAYELEGAVKRADLVIGAV 239 >2UYY-A nrPDB Length = 316 Score = 36.2 bits (82), Expect = 0.021, Method: Composition-based stats. Identities = 13/37 (35%), Positives = 20/37 (54%) Query: 28 KHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILA 64 K + +G GLMG+GI GHTV + ++T + Sbjct: 31 KKIGFLGLGLMGSGIVSNLLKMGHTVTVWNRTAEKCD 67 >3LAD-A nrPDB Length = 476 Score = 35.9 bits (81), Expect = 0.022, Method: Composition-based stats. Identities = 17/95 (17%), Positives = 37/95 (38%), Gaps = 3/95 (3%) Query: 29 HVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKK---KFAEN 85 + VIG G++G + V A G V +++ + L + + + +K+ K K Sbjct: 182 KLGVIGAGVIGLELGSVWARLGAEVTVLEAMDKFLPAVDEQVAKEAQKILTKQGLKILLG 241 Query: 86 LKAGDEFVEKTLSTIATSTDAASVVHSTDLVVEAI 120 + V+ T+ + D ++ A+ Sbjct: 242 ARVTGTEVKNKQVTVKFVDAEGEKSQAFDKLIVAV 276 >6CI9-A nrPDB Length = 259 Score = 35.9 bits (81), Expect = 0.022, Method: Composition-based stats. Identities = 17/72 (23%), Positives = 33/72 (45%), Gaps = 3/72 (4%) Query: 31 TVIGGGL--MGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKKFA-ENLK 87 ++ GG +G GIA+ A G VV+ + +D L ++ + + KV + + + Sbjct: 12 AIVTGGSKGIGRGIAETFANAGVDVVITGRNQDDLDRTVADLSGTRGKVTAVRADVTDPE 71 Query: 88 AGDEFVEKTLST 99 V +T+S Sbjct: 72 DARRTVAETVSR 83 >3ZHB-A nrPDB Length = 309 Score = 35.9 bits (81), Expect = 0.023, Method: Composition-based stats. Identities = 18/57 (31%), Positives = 24/57 (42%) Query: 30 VTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKKFAENL 86 VTVIG GLMG +A GH + ++T +S VA+ A L Sbjct: 22 VTVIGLGLMGQALAGAFLGAGHPTTVWNRTAAKAEPLVARGAKSAGSVAEAVAASPL 78 >5JFC-L nrPDB Length = 474 Score = 35.9 bits (81), Expect = 0.025, Method: Composition-based stats. Identities = 23/90 (25%), Positives = 33/90 (36%), Gaps = 2/90 (2%) Query: 28 KHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEE-SLRKVAKKKFAENL 86 K V +IG G G A A G+ V + + GI E L K KK ENL Sbjct: 155 KKVAIIGAGPAGLTCAADLAKMGYEVTIYEALHQPGGVLIYGIPEFRLPKEIVKKELENL 214 Query: 87 KAGDEFVEKTLSTIATSTDAASVVHSTDLV 116 + +E T + + + D + Sbjct: 215 RRLGVKIE-TNVLVGKTITFEELREEYDAI 243 >2EQ6-A nrPDB Length = 464 Score = 35.9 bits (81), Expect = 0.025, Method: Composition-based stats. Identities = 19/66 (28%), Positives = 33/66 (50%) Query: 16 STASASAKKIIVKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLR 75 ST + ++ + K + VIGGG +G + QV G V L++ +IL + LR Sbjct: 158 STRALKVEEGLPKRLLVIGGGAVGLELGQVYRRLGAEVTLIEYMPEILPQGDPETAALLR 217 Query: 76 KVAKKK 81 + +K+ Sbjct: 218 RALEKE 223 >3DC2-A nrPDB Length = 529 Score = 35.9 bits (81), Expect = 0.026, Method: Composition-based stats. Identities = 26/122 (21%), Positives = 45/122 (36%), Gaps = 10/122 (8%) Query: 11 SVSSSSTASASAKKIIV--KHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKK 68 S+ + +S + K V V+G G +G +AQ AA G VV D ++ Sbjct: 124 SLREHTWKRSSFSGTEIFGKTVGVVGLGRIGQLVAQRIAAFGAYVVAYDPYVSPARAAQL 183 Query: 69 GIE-ESLRKVAKKK------FAENLKAGDEFVEKTLSTIATSTDAASVVHSTDLVVEAIV 121 GIE SL + + + + ++ L+ + LV EA + Sbjct: 184 GIELLSLDDLLARADFISVHLPKTPETAGLIDKEALAKTKPGVIIVNAARGG-LVDEAAL 242 Query: 122 EN 123 + Sbjct: 243 AD 244 >2HMT-A nrPDB Length = 144 Score = 35.9 bits (81), Expect = 0.026, Method: Composition-based stats. Identities = 14/43 (32%), Positives = 19/43 (44%) Query: 23 KKIIVKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAK 65 +I K VIG G G I + GH V+ VD E+ + Sbjct: 2 GRIKNKQFAVIGLGRFGGSIVKELHRMGHEVLAVDINEEKVNA 44 >5BUT-A nrPDB Length = 288 Score = 35.5 bits (80), Expect = 0.027, Method: Composition-based stats. Identities = 14/43 (32%), Positives = 19/43 (44%) Query: 23 KKIIVKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAK 65 +I K VIG G G I + GH V+ VD E+ + Sbjct: 2 GRIKNKQFAVIGLGRFGGSIVKELHRMGHEVLAVDINEEKVNA 44 Score = 35.1 bits (79), Expect = 0.036, Method: Composition-based stats. Identities = 13/38 (34%), Positives = 17/38 (44%) Query: 28 KHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAK 65 K VIG G G I + GH V+ VD E+ + Sbjct: 149 KQFAVIGLGRFGGSIVKELHRMGHEVLAVDINEEKVNA 186 >4DLA-A nrPDB Length = 396 Score = 35.5 bits (80), Expect = 0.027, Method: Composition-based stats. Identities = 12/56 (21%), Positives = 24/56 (42%), Gaps = 3/56 (5%) Query: 14 SSSTASASAKKIIVKHVTVIGGGLMGAGIAQVAAATGH-TVVLVDQTEDILAKSKK 68 + +A + + V V G G +G +A+ A A G ++ +D ++K Sbjct: 201 GAVWNTAKVEPGSI--VAVFGLGTVGLAVAEGAKAAGASRIIGIDIDSKKFDRAKN 254 >5MH6-A nrPDB Length = 308 Score = 35.5 bits (80), Expect = 0.029, Method: Composition-based stats. Identities = 16/89 (17%), Positives = 32/89 (35%), Gaps = 2/89 (2%) Query: 28 KHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKKFAENLK 87 + V V+G G +G G+ AAA G VV V ++ D + ++ + Sbjct: 136 ERVCVVGLGTLGRGVVDRAAALGMEVVGVRRSGDPVDNVSTVYTP--DRLHEAIADARFV 193 Query: 88 AGDEFVEKTLSTIATSTDAASVVHSTDLV 116 + + + + ++ LV Sbjct: 194 VLATPLTDETEGMVAAPEFETMREDASLV 222 >4J90-A nrPDB Length = 222 Score = 35.5 bits (80), Expect = 0.030, Method: Composition-based stats. Identities = 14/43 (32%), Positives = 19/43 (44%) Query: 23 KKIIVKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAK 65 +I K VIG G G I + GH V+ VD E+ + Sbjct: 2 GRIKNKQFAVIGLGRFGGSICKELHRMGHEVLAVDINEEKVNA 44 >5ZIK-A nrPDB Length = 303 Score = 35.1 bits (79), Expect = 0.036, Method: Composition-based stats. Identities = 21/122 (17%), Positives = 42/122 (34%), Gaps = 5/122 (4%) Query: 32 VIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKKFAENLKAGDE 91 ++G G +G+ A G V L+ + L + ++ SL + + + Sbjct: 5 ILGAGSLGSLWAARLGRAGLPVRLILRDRQRLRRYQQAGGLSLVEDGQASLYPIAAETPD 64 Query: 92 FVEKTLSTIATST--DAASVVHSTDLVVEAIVENLKVKNELFKR---LDKFAAEHTIFAS 146 + + DA S + E L ++N L + + +FAS Sbjct: 65 GGQPIQRLLLACKAYDAEEAASSVAHRLAGNAELLLLQNGLGSQQAVAARLPRSRCLFAS 124 Query: 147 NT 148 +T Sbjct: 125 ST 126 >3G0O-A nrPDB Length = 303 Score = 35.1 bits (79), Expect = 0.036, Method: Composition-based stats. Identities = 10/34 (29%), Positives = 14/34 (41%) Query: 29 HVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDI 62 HV ++G G MG G A+ G + D Sbjct: 9 HVGIVGLGSMGMGAARSCLRAGLSTWGADLNPQA 42 >5DT9-A nrPDB Length = 387 Score = 35.1 bits (79), Expect = 0.038, Method: Composition-based stats. Identities = 11/35 (31%), Positives = 19/35 (54%) Query: 28 KHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDI 62 K V +IG G +G+ +A+ + G V+L D + Sbjct: 124 KTVGIIGAGQVGSYLAKCLSGIGMKVLLNDPPKQA 158 >3LXD-A nrPDB Length = 415 Score = 35.1 bits (79), Expect = 0.040, Method: Composition-based stats. Identities = 20/92 (21%), Positives = 36/92 (39%), Gaps = 2/92 (2%) Query: 28 KHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKKFAENLK 87 K+ VIGGG +G A V G V L++ +LA+ + + +L+ Sbjct: 153 KNAVVIGGGYIGLEAAAVLTKFGVNVTLLEALPRVLARVAGEALSEFYQAEHRAHGVDLR 212 Query: 88 AGD--EFVEKTLSTIATSTDAASVVHSTDLVV 117 G + +E + + V D+V+ Sbjct: 213 TGAAMDCIEGDGTKVTGVRMQDGSVIPADIVI 244 >2YQ5-A nrPDB Length = 343 Score = 35.1 bits (79), Expect = 0.041, Method: Composition-based stats. Identities = 10/31 (32%), Positives = 18/31 (58%) Query: 29 HVTVIGGGLMGAGIAQVAAATGHTVVLVDQT 59 V +IG G +G+ +A++ +A G V+ D Sbjct: 150 TVGLIGVGHIGSAVAEIFSAMGAKVIAYDVA 180 >3NJ4-A nrPDB Length = 435 Score = 34.7 bits (78), Expect = 0.047, Method: Composition-based stats. Identities = 30/173 (17%), Positives = 57/173 (32%), Gaps = 31/173 (17%) Query: 29 HVTVI-GGGLMGAGIAQVAAATGHTVVLVDQTE-DILAKSKKGIEESLRKVAKKKFAENL 86 V V+ G G +G G AQ G V++ + + L + +G E + A ++ Sbjct: 217 KVAVVAGYGDVGKGCAQALRGFGARVIITEIDPINALQAAMEGYEVTTMDEACQE-GNIF 275 Query: 87 KAGDEFVEKTLST---------IATSTDAASVVHSTDLVVEAIVENLKVKNEL------- 130 ++ L I + V + E VE + +K ++ Sbjct: 276 VTTTGCIDIILGRHFEQMKDDAIVCNIGHFDVEIDVKWLNENAVEKVNIKPQVDRYRLKN 335 Query: 131 -----------FKRLDKFAAEHTIFASNTSSLQITSIANATTRQDRF-AGLHF 171 L + SN+ + Q+ + T D++ G+HF Sbjct: 336 GRRIILLAEGRLVNLGCAMGHPSFVMSNSFTNQVMAQIELWTHPDKYPVGVHF 388 >4E21-A nrPDB Length = 358 Score = 34.7 bits (78), Expect = 0.048, Method: Composition-based stats. Identities = 20/91 (21%), Positives = 33/91 (36%), Gaps = 8/91 (8%) Query: 29 HVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILA-------KSKKGIEESLRKVAKKK 81 + +IG G MGA + + GH V+ D + + + IEE K+ K + Sbjct: 24 QIGMIGLGRMGADMVRRLRKGGHECVVYDLNVNAVQALEREGIAGARSIEEFCAKLVKPR 83 Query: 82 FAENLKAGDEFVEKTLSTIATSTDAASVVHS 112 L V+ L + A +V Sbjct: 84 VV-WLMVPAAVVDSMLQRMTPLLAANDIVID 113 >5Y77-A nrPDB Length = 473 Score = 34.7 bits (78), Expect = 0.048, Method: Composition-based stats. Identities = 17/61 (27%), Positives = 28/61 (45%), Gaps = 1/61 (1%) Query: 28 KHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTED-ILAKSKKGIEESLRKVAKKKFAENL 86 + VT+IG GL G +A++ A G V L ++ D + +G +L + A L Sbjct: 9 RQVTIIGAGLAGTLVARLLARNGWQVNLFERRPDPRIETGARGRSINLALAERGAHALRL 68 Query: 87 K 87 Sbjct: 69 A 69 >5JXW-A nrPDB Length = 498 Score = 34.7 bits (78), Expect = 0.048, Method: Composition-based stats. Identities = 33/159 (20%), Positives = 60/159 (37%), Gaps = 15/159 (9%) Query: 28 KHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTE-DILAKSKKGIEES-LRKVAKKK--FA 83 K + V+G G +G G AQ + G V++ + L S +G + S L V + F Sbjct: 272 KKIVVLGYGEVGKGCAQGLSGVGARVIVTEIDPICALQASMEGYQVSVLEDVVSEADIFI 331 Query: 84 ENLKAGDEFVEKTLSTIATSTDAASVVHSTDLVVEAIVENL-KVKN-ELFKRLDKFAAEH 141 D + + + + A++ H D + +EN +K E+ + + KF Sbjct: 332 TATGNKDVITVEHMRKMKENAYIANIGHFDDEIDVYGLENYPGIKVIEVKQNVHKFTFPD 391 Query: 142 TIFASNTSSLQITS-----IANATTRQDRFAGLHFFNPV 175 + S + + + AT + F N V Sbjct: 392 ----TQKSVILLCKGRLVNLGCATGHPPLVMSMSFTNQV 426 >4PRK-A nrPDB Length = 336 Score = 34.7 bits (78), Expect = 0.049, Method: Composition-based stats. Identities = 11/31 (35%), Positives = 19/31 (61%) Query: 28 KHVTVIGGGLMGAGIAQVAAATGHTVVLVDQ 58 K + +IG G +G+ +AQ+ +A G V+ D Sbjct: 147 KTIGLIGVGHIGSAVAQIFSAMGAKVLAYDV 177 >6C6P-A nrPDB Length = 458 Score = 34.7 bits (78), Expect = 0.055, Method: Composition-based stats. Identities = 8/43 (18%), Positives = 21/43 (48%) Query: 30 VTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEE 72 V ++G G++G+ +A V + G V ++++ + + Sbjct: 10 VIIVGAGVLGSALAAVLSRDGRKVTVIERDLKEPDRIVGEFLQ 52 >1HL3-A nrPDB Length = 358 Score = 34.7 bits (78), Expect = 0.058, Method: Composition-based stats. Identities = 14/50 (28%), Positives = 25/50 (50%) Query: 9 MRSVSSSSTASASAKKIIVKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQ 58 ++SV ++ A +I + + +IG G +G +A A A G V+ D Sbjct: 153 VQSVEQIREVASGAARIRGETLGIIGLGRVGQAVALRAKAFGFNVLFYDP 202 >1QO8-A nrPDB Length = 566 Score = 34.3 bits (77), Expect = 0.061, Method: Composition-based stats. Identities = 27/134 (20%), Positives = 43/134 (32%), Gaps = 12/134 (8%) Query: 18 ASASAKKIIVKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKV 77 + +A V V+G G G + A G V+LVD+ + I Sbjct: 112 KAIAAGPSETTQVLVVGAGSAGFNASLAAKKAGANVILVDKAP--FSGGNSMISAGGMNA 169 Query: 78 AKKKFAENLKAGDE---FVEKTLST------IATSTDAASVVHSTDLVVEAIVENL-KVK 127 K D+ F+E + I T A +E++ NL +K Sbjct: 170 VGTKQQTAHGVEDKVEWFIEDAMKGGRQQNDIKLVTILAEQSADGVQWLESLGANLDDLK 229 Query: 128 NELFKRLDKFAAEH 141 R+D+ H Sbjct: 230 RSGGARVDRTHRPH 243 >4A6N-B nrPDB Length = 398 Score = 34.3 bits (77), Expect = 0.065, Method: Composition-based stats. Identities = 16/62 (25%), Positives = 28/62 (45%), Gaps = 4/62 (6%) Query: 28 KHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKKFAENLK 87 K+V +IGGG +G +A++ G V + ++ D A+ I + K E +K Sbjct: 27 KNVAIIGGGPVGLTMAKLLQQNGIDVSVYERDNDREAR----IFGGTLDLHKGSGQEAMK 82 Query: 88 AG 89 Sbjct: 83 KA 84 >5N2I-A nrPDB Length = 232 Score = 34.3 bits (77), Expect = 0.067, Method: Composition-based stats. Identities = 16/67 (23%), Positives = 30/67 (44%), Gaps = 1/67 (1%) Query: 9 MRSVSSSSTASASAKKIIVKHVTVIGG-GLMGAGIAQVAAATGHTVVLVDQTEDILAKSK 67 M + +S ++ + + V+GG G G G+A+ A GH V+L ++ + Sbjct: 1 MIMIMASKSSPHDLPDVSGLSIAVLGGTGDQGRGLARRFAMAGHEVILGSRSAERAQAVA 60 Query: 68 KGIEESL 74 + E L Sbjct: 61 AELGEGL 67 >2W8Z-A nrPDB Length = 470 Score = 34.3 bits (77), Expect = 0.068, Method: Composition-based stats. Identities = 22/115 (19%), Positives = 47/115 (40%), Gaps = 8/115 (6%) Query: 29 HVTVIGGGLMGAGIAQVAAATGHTVVLV----DQTEDILAKSK-KGIEESLRKVAKKKFA 83 + VIG +MG +A + G++V + ++T++ L ++K K I + Sbjct: 6 QIGVIGLAVMGKNLALNIESKGYSVAVYNRLREKTDEFLQEAKGKNIVGTYSIEEFVNAL 65 Query: 84 ENLKAGDEFVEKTLSTIATSTDAASVVHSTDLVVE---AIVENLKVKNELFKRLD 135 E + V+ T AT + D+V++ ++ + +N+ L Sbjct: 66 EKPRKILLMVKAGAPTDATIEQLKPHLEKGDIVIDGGNTYFKDTQRRNKELAELG 120 >3DAF-A nrPDB Length = 358 Score = 34.3 bits (77), Expect = 0.071, Method: Composition-based stats. Identities = 28/153 (18%), Positives = 55/153 (35%), Gaps = 8/153 (5%) Query: 56 VDQTEDILAKSKKGIEESLRKVAKKKFAENLKAGDEFVEKTLS---TIATSTDAASVVHS 112 + E L+ + + I +R+V K K E K + + ++D V Sbjct: 82 KEVMEAHLSGNPESIMPKIREVVKAKAKELPKPPKACIHLVHPEDVGLKVTSDDREAVEG 141 Query: 113 TDLVVEAIVENLKVKNELFKRLDKFAAEHTIFASNTSSLQIT---SIANATTRQDRFAGL 169 D+V+ + + + ++ K+ E I ++ ++ T I R+D Sbjct: 142 ADIVITWLPKG-NKQPDIIKKFADAIPEGAIV-THACTIPTTKFAKIFKDLGREDLNITS 199 Query: 170 HFFNPVPVMKLVEVIKTPMTSQKTFESLVDFSK 202 + VP MK I S++ L + K Sbjct: 200 YHPGCVPEMKGQVYIAEGYASEEAVNKLYEIGK 232 >5UYY-A nrPDB Length = 381 Score = 34.3 bits (77), Expect = 0.077, Method: Composition-based stats. Identities = 19/82 (23%), Positives = 37/82 (45%), Gaps = 8/82 (9%) Query: 28 KHVTVIGGGLMGAGIAQVAAATGHTVVL--VDQTEDILAKSKK-----GIEESLRKVAKK 80 K V +IG GL+G +A +A H V + D ++ + ++K+ I L+ ++ Sbjct: 18 KKVVLIGTGLIGGSLA-LAIKKDHDVTITGYDIFQEQVERAKELHVVDEIAVDLQHACEE 76 Query: 81 KFAENLKAGDEFVEKTLSTIAT 102 + E +K L +A+ Sbjct: 77 AHLIVFASPVEETKKLLHKLAS 98 >1SEZ-A nrPDB Length = 504 Score = 33.9 bits (76), Expect = 0.083, Method: Composition-based stats. Identities = 15/64 (23%), Positives = 24/64 (37%), Gaps = 5/64 (7%) Query: 11 SVSSSSTASASAKKIIVKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGI 70 + S+ +SA K V VIG G+ G A G V + + K + Sbjct: 2 APSAGEDKHSSA-----KRVAVIGAGVSGLAAAYKLKIHGLNVTVFEAEGKAGGKLRSVS 56 Query: 71 EESL 74 ++ L Sbjct: 57 QDGL 60 >3ZZN-A nrPDB Length = 310 Score = 33.9 bits (76), Expect = 0.084, Method: Composition-based stats. Identities = 13/44 (29%), Positives = 20/44 (45%), Gaps = 2/44 (4%) Query: 29 HVTVIGGGLMGAGIAQVAAATGH--TVVLVDQTEDILAKSKKGI 70 V ++G G++G+ A A G VVLVD + + I Sbjct: 2 KVGIVGSGMVGSATAYALALLGVAREVVLVDLDRKLAQAHAEDI 45 >4FFM-A nrPDB Length = 363 Score = 33.9 bits (76), Expect = 0.085, Method: Composition-based stats. Identities = 13/39 (33%), Positives = 21/39 (53%) Query: 27 VKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAK 65 +K + ++GG L G A ++ G VVLVD+ L + Sbjct: 1 MKTICLVGGKLQGFEAAYLSKKAGMKVVLVDKNPQALIR 39 >1CF2-P nrPDB Length = 337 Score = 33.9 bits (76), Expect = 0.091, Method: Composition-based stats. Identities = 18/108 (16%), Positives = 40/108 (37%), Gaps = 9/108 (8%) Query: 27 VKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKKFAENL 86 +K V + G G +G +A + ++ SK + R KK + + Sbjct: 1 MKAVAINGYGTVGKRVADA--------IAQQDDMKVIGVSKTRPDFEARMALKKGYDLYV 52 Query: 87 KAGDEFVEKTLSTIATSTDAASVVHSTDLVVEAIVENLKVKN-ELFKR 133 + + I + ++ D+V++ E + KN +++K Sbjct: 53 AIPERVKLFEKAGIEVAGTVDDMLDEADIVIDCTPEGIGAKNLKMYKE 100 >5TR3-A nrPDB Length = 481 Score = 33.5 bits (75), Expect = 0.11, Method: Composition-based stats. Identities = 14/72 (19%), Positives = 28/72 (38%) Query: 28 KHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKKFAENLK 87 K + VIG G++G + V A G V +++ + L + + + +K K+ + Sbjct: 185 KRLGVIGAGVIGLELGSVWARLGAEVTVLEALDTFLMAADTAVSKEAQKTLTKQGLDIKL 244 Query: 88 AGDEFVEKTLST 99 K Sbjct: 245 GARVTGSKVNGN 256 >4OQY-A nrPDB Length = 290 Score = 33.5 bits (75), Expect = 0.11, Method: Composition-based stats. Identities = 12/38 (31%), Positives = 17/38 (44%) Query: 28 KHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAK 65 + VTVIG G MG + GH V + ++T Sbjct: 4 QSVTVIGLGPMGQAMVNTFLDNGHEVTVWNRTASKAEA 41 >3K30-A nrPDB Length = 690 Score = 33.5 bits (75), Expect = 0.11, Method: Composition-based stats. Identities = 30/154 (19%), Positives = 49/154 (31%), Gaps = 15/154 (9%) Query: 16 STASASAK-KIIVKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESL 74 + K V V+G G G A+ G+ VVL + D+ + + Sbjct: 379 GWHPERIRAKESDARVLVVGAGPSGLEAARALGVRGYDVVLAEAGRDLGGR--------V 430 Query: 75 RKVAKKKFAENLKAGDEFVEKTLSTIATSTDAASVVHSTDLVVEAIVENLKVKNELFKRL 134 + + E+ E L+ + + D +VE E++ R Sbjct: 431 TQESALPGLSAWGRVKEYREAVLAELPNVEIYRESPMTGDDIVEFGFEHVITATGATWRT 490 Query: 135 DKFAAEHTIFASNTSSLQITSIANATTRQDRFAG 168 D A H T++L I D FAG Sbjct: 491 DGVARFH------TTALPIAEGMQVLGPDDLFAG 518 >4OH1-A nrPDB Length = 351 Score = 33.5 bits (75), Expect = 0.12, Method: Composition-based stats. Identities = 21/115 (18%), Positives = 46/115 (40%), Gaps = 6/115 (5%) Query: 8 FMRSVSSSSTASASAKKIIVKHVTVIGGGLMGAGIAQVAAATGHTVV-LVDQTEDILAKS 66 + ++ + +++ AK K V ++G G +G + Q+A G + + + D + L + Sbjct: 155 LVEPLTVALSSAEQAKISYGKSVAIMGAGGLGMMLVQLARLAGASTITVFDIVPEKLELA 214 Query: 67 KKG-----IEESLRKVAKKKFAENLKAGDEFVEKTLSTIATSTDAASVVHSTDLV 116 + + + VA++ D +E T +T A + D V Sbjct: 215 LENGADYALNSAEEGVAERAIELAGGRYDCVLEGTGATAAAKLGLQLLARDGDAV 269 >1LTH-T nrPDB Length = 319 Score = 33.2 bits (74), Expect = 0.14, Method: Composition-based stats. Identities = 12/40 (30%), Positives = 20/40 (50%), Gaps = 2/40 (5%) Query: 28 KHVTVIGGGLMGAGIAQVAAATGH--TVVLVDQTEDILAK 65 + VIG G +G+ +A AA G +VL D ++ + Sbjct: 8 TKLAVIGAGAVGSTLAFAAAQRGIAREIVLEDIAKERVEA 47 >4HTF-A nrPDB Length = 285 Score = 33.2 bits (74), Expect = 0.14, Method: Composition-based stats. Identities = 19/118 (16%), Positives = 44/118 (37%), Gaps = 15/118 (12%) Query: 28 KHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKKFAENLK 87 + + V+ G A A GH V+L D + ++ ++K+ E K ++N++ Sbjct: 68 QKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEA-------KGVSDNMQ 120 Query: 88 AGDEFVEKTLSTIATSTDAASVVHSTDLVVEAIVENLKVKNELFKRLDKFAAEHTIFA 145 + S + T D ++ A++E + + + L + + Sbjct: 121 FIHCAAQDVASHLETPVDL--------ILFHAVLEWVADPRSVLQTLWSVLRPGGVLS 170 >2EEZ-A nrPDB Length = 369 Score = 33.2 bits (74), Expect = 0.15, Method: Composition-based stats. Identities = 19/92 (20%), Positives = 33/92 (35%), Gaps = 22/92 (23%) Query: 29 HVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKKFAENLKA 88 V ++GGG +G A++A G V ++D L Sbjct: 168 SVVILGGGTVGTNAAKIALGMGAQVTILDVNHKRLQ----------------------YL 205 Query: 89 GDEFVEKTLSTIATSTDAASVVHSTDLVVEAI 120 D F + ++ AT + V DL++ A+ Sbjct: 206 DDVFGGRVITLTATEANIKKSVQHADLLIGAV 237 >3WFI-A nrPDB Length = 312 Score = 33.2 bits (74), Expect = 0.15, Method: Composition-based stats. Identities = 23/126 (18%), Positives = 54/126 (42%), Gaps = 6/126 (4%) Query: 29 HVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKK-GIEESLR-KVAKKKFAENL 86 + + G G MG+ + +G+ V+L+D + + + K+ G++ + K + K L Sbjct: 2 KIAIAGAGAMGSRFGLMLHQSGNEVLLIDGWAEHVQQIKEHGLQANFNGKEVEAKLPIVL 61 Query: 87 KAGDEFVEKTLSTIATS--TDAASVVHSTDLVVEAIVENLKVKNELFKR--LDKFAAEHT 142 ++ E ++ I + ++ +++ E L + N + ++KF Sbjct: 62 QSEVEKEDQVDLIILFTKAMQLEKMLQDIQSLIKKDTEVLCLLNGIGHEDIIEKFVPMEN 121 Query: 143 IFASNT 148 I+ NT Sbjct: 122 IYIGNT 127 >2DFV-A nrPDB Length = 347 Score = 33.2 bits (74), Expect = 0.15, Method: Composition-based stats. Identities = 14/61 (22%), Positives = 29/61 (47%), Gaps = 1/61 (1%) Query: 9 MRSVSSSSTASASAKKIIVKHVTVIGGGLMG-AGIAQVAAATGHTVVLVDQTEDILAKSK 67 ++ ++ + A I K V + G G +G GIA A+ + V++ + ++ +K Sbjct: 149 LQEPLGNAVDTVLAGPISGKSVLITGAGPLGLLGIAVAKASGAYPVIVSEPSDFRRELAK 208 Query: 68 K 68 K Sbjct: 209 K 209 >2PA3-A nrPDB Length = 410 Score = 33.2 bits (74), Expect = 0.15, Method: Composition-based stats. Identities = 27/155 (17%), Positives = 53/155 (34%), Gaps = 13/155 (8%) Query: 28 KHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEE-----SLRKVAKKKF 82 K + +IG G +G + +A + G V D + + ++ ++ V Sbjct: 152 KKLGIIGYGHIGTQLGILAESLGMYVYFYDIENKLPLGNATQVQHLSDLLNMSDVVSLHV 211 Query: 83 AENLKAGDEFVEKTLSTIATSTDAASVVHSTDLVVEAIVENLKVKNELFKRLDKFAAE-- 140 EN + K +S + + + T + + A+ + L K+ +D F E Sbjct: 212 PENPSTKNMMGAKEISLMKPGSLLINASRGTVVDIPALADALASKHLAGAAIDVFPTEPA 271 Query: 141 ------HTIFASNTSSLQITSIANATTRQDRFAGL 169 + A + L I +T GL Sbjct: 272 TNSDPFTSPLAEFDNVLLTPHIGGSTQEAQENIGL 306 >1AHH-A nrPDB Length = 255 Score = 33.2 bits (74), Expect = 0.15, Method: Composition-based stats. Identities = 12/42 (28%), Positives = 18/42 (42%), Gaps = 1/42 (2%) Query: 32 VIGGGL-MGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEE 72 + G G +G IA A G +VV+ D D I++ Sbjct: 16 ITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQ 57 >3H5A-A nrPDB Length = 358 Score = 33.2 bits (74), Expect = 0.15, Method: Composition-based stats. Identities = 24/121 (19%), Positives = 45/121 (37%), Gaps = 6/121 (4%) Query: 5 TRQFMRSVSSSSTASASAKKIIVKHVTVIGGGLMGAGIAQVAAATGH-TVVLVDQTEDIL 63 +R F+ S + K+ V ++G G +G ++ + A +G ++L+D + Sbjct: 93 SRNFLHYQSYGANPVLVQDKLKNAKVVILGCGGIGNHVSVILATSGIGEIILIDNDQIEN 152 Query: 64 AKSKKGIEESLRKVAKKKFAENLKA-----GDEFVEKTLSTIATSTDAASVVHSTDLVVE 118 + + S V K K + + V + I TD V + VV Sbjct: 153 TNLTRQVLFSEDDVGKNKTEVIKRELLKRNSEISVSEIALNINDYTDLHKVPEADIWVVS 212 Query: 119 A 119 A Sbjct: 213 A 213 >3WSV-A nrPDB Length = 322 Score = 33.2 bits (74), Expect = 0.16, Method: Composition-based stats. Identities = 17/107 (15%), Positives = 37/107 (34%), Gaps = 3/107 (2%) Query: 28 KHVTVIGGGLMGAGIAQVAAATGH--TVVLVDQTEDILAKSKKGIEESLRKVAKKKFAEN 85 + V ++G G +G IA G +VL+D ++ + + + +K + Sbjct: 6 RKVVIVGTGFVGTSIAYAMINQGVANELVLIDVNQEKAEGEALDLLDGMAW-GEKNVSVW 64 Query: 86 LKAGDEFVEKTLSTIATSTDAASVVHSTDLVVEAIVENLKVKNELFK 132 +E + L + + DLV ++ E+ Sbjct: 65 SGTYEECQDANLVILTAGVNQKPGQTRLDLVKTNATITRQIVKEVMA 111 >4ND4-A nrPDB Length = 321 Score = 33.2 bits (74), Expect = 0.16, Method: Composition-based stats. Identities = 20/91 (21%), Positives = 31/91 (34%), Gaps = 19/91 (20%) Query: 28 KHVTVIGGGLMGAGIAQVAAATGHT-VVLVDQTEDILAKSKKGIEESLRKVAKKKFAENL 86 + + VIG G +G IA + VVL D E I I S+ Sbjct: 5 RKIAVIGSGQIGGNIAYIVGKDNLADVVLFDIAEGIPQGKALDITHSMVMFGST------ 58 Query: 87 KAGDEFVEKTLSTIATSTDAASVVHSTDLVV 117 S + + D A + +D+V+ Sbjct: 59 -----------SKVIGTNDYAD-ISGSDVVI 77 >3HWR-A nrPDB Length = 318 Score = 33.2 bits (74), Expect = 0.16, Method: Composition-based stats. Identities = 21/92 (22%), Positives = 39/92 (42%), Gaps = 18/92 (19%) Query: 29 HVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKKFAENLKA 88 V ++G G +G + A GH V+L+ + + IE + ++ + F E +K Sbjct: 21 KVAIMGAGAVGCYYGGMLARAGHEVILI-----ARPQHVQAIEATGLRLETQSFDEQVK- 74 Query: 89 GDEFVEKTLSTIATSTDAASVVHSTDLVVEAI 120 ++ S+D S V DLV+ + Sbjct: 75 -----------VSASSD-PSAVQGADLVLFCV 94 >5OCM-A nrPDB Length = 291 Score = 33.2 bits (74), Expect = 0.16, Method: Composition-based stats. Identities = 19/87 (21%), Positives = 33/87 (37%), Gaps = 2/87 (2%) Query: 30 VTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKKFAENLKAG 89 VTV+G GLMG +A GH + +++E + + ++ + + AE Sbjct: 6 VTVLGLGLMGQALAGAFLKDGHATTVWNRSEG--KAGQLAEQGAVLASSARDAAEASPLV 63 Query: 90 DEFVEKTLSTIATSTDAASVVHSTDLV 116 V + A V+ LV Sbjct: 64 VVCVSDHAAVRAVLDPLGDVLAGRVLV 90 >2EW2-A nrPDB Length = 316 Score = 33.2 bits (74), Expect = 0.17, Method: Composition-based stats. Identities = 10/41 (24%), Positives = 19/41 (46%) Query: 29 HVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKG 69 + + G G MG+ + + G+ V L+DQ + +K Sbjct: 5 KIAIAGAGAMGSRLGIMLHQGGNDVTLIDQWPAHIEAIRKN 45 >3PEF-A nrPDB Length = 287 Score = 32.8 bits (73), Expect = 0.18, Method: Composition-based stats. Identities = 8/37 (21%), Positives = 19/37 (51%) Query: 28 KHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILA 64 + IG G+MG+ +A+ G +V + +++ + Sbjct: 2 QKFGFIGLGIMGSAMAKNLVKAGCSVTIWNRSPEKAE 38 >2AVN-A nrPDB Length = 260 Score = 32.8 bits (73), Expect = 0.18, Method: Composition-based stats. Identities = 24/116 (20%), Positives = 44/116 (37%), Gaps = 24/116 (20%) Query: 29 HVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKKFAENLKA 88 V +GGG + G VVLVD ++++L ++ E+ ++ V + K AE+L Sbjct: 57 RVLDLGGGT--GKWSLFLQERGFEVVLVDPSKEMLEVAR---EKGVKNVVEAK-AEDLPF 110 Query: 89 GDEFVEKTLSTIATSTDAASVVHSTDLVVEAIVENLKVKNELFKRLDKFAAEHTIF 144 E L+ D S V + K++ F + + + Sbjct: 111 PSGAFEAVLAL----GDVLSYVEN--------------KDKAFSEIRRVLVPDGLL 148 >1Q1R-A nrPDB Length = 431 Score = 32.8 bits (73), Expect = 0.20, Method: Composition-based stats. Identities = 18/94 (19%), Positives = 35/94 (37%), Gaps = 4/94 (4%) Query: 28 KHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKKFAENLK 87 + VIGGG +G +A A V L+D +L + + + ++ +++ Sbjct: 150 NRLVVIGGGYIGLEVAATAIKANMHVTLLDTAARVLERVTAPPVSAFYEHLHREAGVDIR 209 Query: 88 AGDEFVEKTLST----IATSTDAASVVHSTDLVV 117 G + +ST + DLV+ Sbjct: 210 TGTQVCGFEMSTDQQKVTAVLCEDGTRLPADLVI 243 >1V9L-A nrPDB Length = 421 Score = 32.8 bits (73), Expect = 0.20, Method: Composition-based stats. Identities = 23/98 (23%), Positives = 37/98 (37%), Gaps = 6/98 (6%) Query: 28 KHVTVIGGGLMGAGIAQVAAATGHTVVLV-DQTEDILAKSKKGIEESLRKVAKKKFAENL 86 K V + G G +G A G V+ V D K+G+ ++ + K K Sbjct: 211 KTVAIQGMGNVGRWTAYWLEKMGAKVIAVSDINGVAYR--KEGL--NVELIQKNKGLTGP 266 Query: 87 KAGDEFVEKTLSTIATSTDAASVVHSTDLVVEAIVENL 124 + F K + + D A D+ V A +EN+ Sbjct: 267 ALVELFTTKDNAEFVKNPD-AIFKLDVDIFVPAAIENV 303 >2CZG-A nrPDB Length = 433 Score = 32.8 bits (73), Expect = 0.20, Method: Composition-based stats. Identities = 15/48 (31%), Positives = 24/48 (50%), Gaps = 5/48 (10%) Query: 15 SSTASASAKKIIVKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDI 62 + + SA+KI++ +G G +G IA A G VV VD+ + Sbjct: 12 GTATTDSAQKILL-----LGSGELGKEIAIEAQRLGVEVVAVDRYANA 54 >2V3B-A nrPDB Length = 384 Score = 32.8 bits (73), Expect = 0.21, Method: Composition-based stats. Identities = 22/111 (19%), Positives = 46/111 (41%), Gaps = 12/111 (10%) Query: 15 SSTASASAKKIIVKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDIL-----AKSKKG 69 + A+A K + V ++G GL+G A ++ G+ + +V E ++ + K Sbjct: 136 ARFRQAAAGK---RRVLLLGAGLIGCEFANDLSSGGYQLDVVAPCEQVMPGLLHPAAAKA 192 Query: 70 IEESLRKVAKKKFAENLKAGDEFVEKTLSTIATSTDAASVVHSTDLVVEAI 120 ++ L + + + A + + L + + V DLVV A+ Sbjct: 193 VQAGLEGLGVRFHLGPVLASLKKAGEGLE----AHLSDGEVIPCDLVVSAV 239 >4UEJ-A nrPDB Length = 346 Score = 32.8 bits (73), Expect = 0.21, Method: Composition-based stats. Identities = 16/61 (26%), Positives = 28/61 (45%), Gaps = 1/61 (1%) Query: 8 FMRSVSSSSTASASAKKIIVKHVTVIGGGLMG-AGIAQVAAATGHTVVLVDQTEDILAKS 66 F+ ++ A A+ K+V +IG G +G I A +V +D + + LA + Sbjct: 142 FIEPITVGLHAFHLAQGCENKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLALA 201 Query: 67 K 67 K Sbjct: 202 K 202 >4ZGS-A nrPDB Length = 386 Score = 32.8 bits (73), Expect = 0.22, Method: Composition-based stats. Identities = 12/50 (24%), Positives = 21/50 (42%) Query: 28 KHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKV 77 K V V+G G +G A++ G V D + ++ SL ++ Sbjct: 179 KVVGVVGTGAIGQQAARILKGIGCKVFAYDIKPNPAVEAMGIPYVSLDEL 228 >3Q3C-A nrPDB Length = 299 Score = 32.8 bits (73), Expect = 0.22, Method: Composition-based stats. Identities = 10/38 (26%), Positives = 18/38 (47%) Query: 27 VKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILA 64 +K + IG G MGA +A G+ + + D + + Sbjct: 2 MKQIAFIGLGHMGAPMATNLLKAGYLLNVFDLVQSAVD 39 >4ZCC-A nrPDB Length = 336 Score = 32.8 bits (73), Expect = 0.22, Method: Composition-based stats. Identities = 11/30 (36%), Positives = 17/30 (56%) Query: 30 VTVIGGGLMGAGIAQVAAATGHTVVLVDQT 59 + +IG G+ G AQ + GH V L D++ Sbjct: 5 IAIIGTGIAGLSAAQALTSAGHQVHLFDKS 34 >3KKJ-A nrPDB Length = 336 Score = 32.8 bits (73), Expect = 0.23, Method: Composition-based stats. Identities = 12/30 (40%), Positives = 17/30 (56%) Query: 30 VTVIGGGLMGAGIAQVAAATGHTVVLVDQT 59 + +IG G+ G AQ A GH V L D++ Sbjct: 5 IAIIGTGIAGLSAAQALTAAGHQVHLFDKS 34 >3TL2-A nrPDB Length = 315 Score = 32.4 bits (72), Expect = 0.23, Method: Composition-based stats. Identities = 35/157 (22%), Positives = 55/157 (35%), Gaps = 31/157 (19%) Query: 28 KHVTVIGGGLMGAGIAQVAAATGHT-VVLVDQTEDILAKSKKGIEESLRKVAKKKFAENL 86 K V+VIG G GA A + A VVLVD + L K K + L Sbjct: 9 KKVSVIGAGFTGATTAFLLAQKELADVVLVDIPQ-------------LENPTKGKALDML 55 Query: 87 KAGDEFVEKTLSTIATSTDAASVVHSTDLVVEA-------------IVENLKVKNELFKR 133 +A V+ + I ++D A S +V+ A + N K+ + + Sbjct: 56 EASP--VQGFDANIIGTSDYADTADSDVVVITAGIARKPGMSRDDLVATNSKIMKSITRD 113 Query: 134 LDKFAAEHTIFA-SNTSSLQITSIANATTRQ-DRFAG 168 + K + I +N S+ +R G Sbjct: 114 IAKHSPNAIIVVLTNPVDAMTYSVFKEAGFPKERVIG 150 >1A5Z-A nrPDB Length = 319 Score = 32.4 bits (72), Expect = 0.25, Method: Composition-based stats. Identities = 26/147 (17%), Positives = 51/147 (34%), Gaps = 25/147 (17%) Query: 29 HVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKKFAENLKA 88 + ++G G +G+ A G +++ + + K + A +L Sbjct: 2 KIGIVGLGRVGSSTAFALLMKGF--------------AREMVLIDVDKKRAEGDALDLIH 47 Query: 89 GDEFVEKTLSTIATSTDAASVVHSTDLVVEA--IVENL-KVKNELFKRLDKFAAEHTIFA 145 G F + + D A + +D+V+ A + + + + +L R + E A Sbjct: 48 GTPFTRRAN---IYAGDYADL-KGSDVVIVAAGVPQKPGETRLQLLGRNARVMKE---IA 100 Query: 146 SNTSSLQITSIANATTRQDRFAGLHFF 172 N S SI T +FF Sbjct: 101 RNVSKYAPDSIVIVVTNPVDVL-TYFF 126 >3UPY-A nrPDB Length = 445 Score = 32.4 bits (72), Expect = 0.27, Method: Composition-based stats. Identities = 20/105 (19%), Positives = 35/105 (33%), Gaps = 6/105 (5%) Query: 16 STASASAKKIIVKHVTVIGGGLMGAGIAQVAAA-TGHTVVLVDQTEDILAKSKKGIEESL 74 + + + K I + +IG G MG I A G V + L + K I + Sbjct: 15 AARAETGKPI---RIGLIGAGEMGTDIVTQVARMQGIEVGA--LSARRLPNTFKAIRTAY 69 Query: 75 RKVAKKKFAENLKAGDEFVEKTLSTIATSTDAASVVHSTDLVVEA 119 + A A +E + D D++++A Sbjct: 70 GDEENAREATTESAMTRAIEAGKIAVTDDNDLILSNPLIDVIIDA 114 >5VJ7-A nrPDB Length = 476 Score = 32.0 bits (71), Expect = 0.31, Method: Composition-based stats. Identities = 10/31 (32%), Positives = 14/31 (45%) Query: 28 KHVTVIGGGLMGAGIAQVAAATGHTVVLVDQ 58 K V +IG G G A A G+ V + + Sbjct: 155 KKVAIIGAGPAGLTCAADLAKMGYEVTIYEA 185 >3KB6-A nrPDB Length = 334 Score = 32.0 bits (71), Expect = 0.32, Method: Composition-based stats. Identities = 15/53 (28%), Positives = 25/53 (47%) Query: 29 HVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKK 81 + VIG G +G+ +A A G V+ D + K K + SL ++ K+ Sbjct: 143 TLGVIGTGRIGSRVAMYGLAFGMKVLCYDVVKREDLKEKGCVYTSLDELLKES 195 >3DOJ-A nrPDB Length = 310 Score = 32.0 bits (71), Expect = 0.35, Method: Composition-based stats. Identities = 21/96 (21%), Positives = 40/96 (41%), Gaps = 9/96 (9%) Query: 27 VKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKKFAENL 86 + V +G G+MG ++ G V + ++T L+K + +E E+ Sbjct: 21 MMEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRT---LSKCDELVEHG------ASVCESP 71 Query: 87 KAGDEFVEKTLSTIATSTDAASVVHSTDLVVEAIVE 122 + + T++ ++ A SVV V+E I E Sbjct: 72 AEVIKKCKYTIAMLSDPCAALSVVFDKGGVLEQICE 107 >4JJI-A nrPDB Length = 378 Score = 32.0 bits (71), Expect = 0.36, Method: Composition-based stats. Identities = 11/56 (19%), Positives = 23/56 (41%), Gaps = 3/56 (5%) Query: 14 SSSTASASAKKIIVKHVTVIGGGLMGAGIAQVAAATGH-TVVLVDQTEDILAKSKK 68 + +A + +V + G G +G +A+ A G ++ +D +KK Sbjct: 183 GAVWNTAKVEPG--SNVAIFGLGTVGLAVAEGAKTAGASRIIGIDIDSKKYETAKK 236 >3ATQ-A nrPDB Length = 453 Score = 32.0 bits (71), Expect = 0.38, Method: Composition-based stats. Identities = 11/31 (35%), Positives = 16/31 (51%) Query: 30 VTVIGGGLMGAGIAQVAAATGHTVVLVDQTE 60 V +IGGG G+ A + G ++LVD Sbjct: 9 VLIIGGGFAGSSAAYQLSRRGLKILLVDSKP 39 >5X68-A nrPDB Length = 391 Score = 32.0 bits (71), Expect = 0.39, Method: Composition-based stats. Identities = 13/34 (38%), Positives = 18/34 (52%) Query: 28 KHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTED 61 K V VIGGGL+G+ A A + + + ED Sbjct: 15 KKVAVIGGGLVGSLQACFLAKRNFQIDVYEARED 48 >3ETH-A nrPDB Length = 355 Score = 31.6 bits (70), Expect = 0.39, Method: Composition-based stats. Identities = 15/71 (21%), Positives = 26/71 (36%), Gaps = 2/71 (2%) Query: 27 VKHVTVIGGGLMGAGIAQVAAATGHTV--VLVDQTEDILAKSKKGIEESLRKVAKKKFAE 84 +K V V+G G +G + Q G V V +D + + I + + + Sbjct: 1 MKQVCVLGNGQLGRMLRQAGEPLGIAVWPVGLDAEPAAVPFQQSVITAEIERWPETALTR 60 Query: 85 NLKAGDEFVEK 95 L FV + Sbjct: 61 QLARHPAFVNR 71 >3PDU-A nrPDB Length = 287 Score = 31.6 bits (70), Expect = 0.41, Method: Composition-based stats. Identities = 7/35 (20%), Positives = 14/35 (40%) Query: 27 VKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTED 61 + +G G+MG +A G V + ++ Sbjct: 1 MTTYGFLGLGIMGGPMAANLVRAGFDVTVWNRNPA 35 >1YB4-A nrPDB Length = 295 Score = 31.6 bits (70), Expect = 0.42, Method: Composition-based stats. Identities = 9/34 (26%), Positives = 15/34 (44%) Query: 29 HVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDI 62 + IG G+MG+ +A A GH + + Sbjct: 5 KLGFIGLGIMGSPMAINLARAGHQLHVTTIGPVA 38 >4TSK-A nrPDB Length = 350 Score = 31.6 bits (70), Expect = 0.44, Method: Composition-based stats. Identities = 12/35 (34%), Positives = 17/35 (48%) Query: 21 SAKKIIVKHVTVIGGGLMGAGIAQVAAATGHTVVL 55 S + + K + VIG G G AQ +G VV+ Sbjct: 11 SIQPLADKRIAVIGYGSQGHAHAQNLRDSGFDVVI 45 >4K28-A nrPDB Length = 269 Score = 31.6 bits (70), Expect = 0.44, Method: Composition-based stats. Identities = 14/59 (23%), Positives = 22/59 (37%), Gaps = 7/59 (11%) Query: 8 FMRSVSSSSTASASAKKIIVKHVTVIGGGLMGAGIAQVAAATGH-TVVLVDQTEDILAK 65 F+ + A K VIG G +G+ IA A G ++ L D + + Sbjct: 112 FLGAAHKHGFEPAG------KRALVIGCGGVGSAIAYALAEAGIASITLCDPSTARMGA 164 >1C0L-A nrPDB Length = 363 Score = 31.6 bits (70), Expect = 0.45, Method: Composition-based stats. Identities = 13/36 (36%), Positives = 20/36 (55%), Gaps = 2/36 (5%) Query: 28 KHVTVIGGGLMGAGIAQVAAATGHTV--VLVDQTED 61 K V V+G G++G A + A G++V + D ED Sbjct: 7 KRVVVLGSGVIGLSSALILARKGYSVHILARDLPED 42 >4MIE-A nrPDB Length = 351 Score = 31.6 bits (70), Expect = 0.46, Method: Composition-based stats. Identities = 15/51 (29%), Positives = 22/51 (43%), Gaps = 3/51 (5%) Query: 26 IVKHVTVIGGGLMGAG-IAQVA-AATGHTVVLV-DQTEDILAKSKKGIEES 73 +V V VIG G MG I ++ TG VV V D + + + + Sbjct: 13 MVVKVGVIGTGAMGRAHIDRLTNVLTGAEVVAVTDIDHEAAEAAVRDFHLN 63 >2R9Z-A nrPDB Length = 463 Score = 31.6 bits (70), Expect = 0.47, Method: Composition-based stats. Identities = 17/94 (18%), Positives = 38/94 (40%), Gaps = 1/94 (1%) Query: 28 KHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESL-RKVAKKKFAENL 86 K V +IG G +G +A + + G V +V + +L + + +L + + +L Sbjct: 167 KRVAIIGAGYIGIELAGLLRSFGSEVTVVALEDRLLFQFDPLLSATLAENMHAQGIETHL 226 Query: 87 KAGDEFVEKTLSTIATSTDAASVVHSTDLVVEAI 120 + +E+ + + D V+ A+ Sbjct: 227 EFAVAALERDAQGTTLVAQDGTRLEGFDSVIWAV 260 >3D2L-A nrPDB Length = 243 Score = 31.6 bits (70), Expect = 0.49, Method: Composition-based stats. Identities = 19/77 (24%), Positives = 36/77 (46%), Gaps = 4/77 (5%) Query: 2 AFVTRQFMRSVSSSSTASASAKKI-IVKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTE 60 A+V + M+ V + +++ K + IG G G A + A + V VD +E Sbjct: 8 AYVYDELMQDVPYPEWVAWVLEQVEPGKRIADIGCGT---GTATLLLADHYEVTGVDLSE 64 Query: 61 DILAKSKKGIEESLRKV 77 ++L +++ E+ R V Sbjct: 65 EMLEIAQEKAMETNRHV 81 >2OME-A nrPDB Length = 336 Score = 31.2 bits (69), Expect = 0.53, Method: Composition-based stats. Identities = 19/66 (28%), Positives = 30/66 (45%), Gaps = 6/66 (9%) Query: 9 MRSVSSSSTASASAKKIIVKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKK 68 ++SV ++ A +I + + +IG G G +A A A G +V+ D Sbjct: 134 VQSVEQIREVASGAARIRGETLGLIGFGRTGQAVAVRAKAFGFSVIFYDPYLQ------D 187 Query: 69 GIEESL 74 GIE SL Sbjct: 188 GIERSL 193 >3KYB-A nrPDB Length = 390 Score = 31.2 bits (69), Expect = 0.55, Method: Composition-based stats. Identities = 12/33 (36%), Positives = 19/33 (57%) Query: 28 KHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTE 60 K + ++G G GA I + A GH V ++DQ + Sbjct: 4 KKILIVGAGFSGAVIGRQLAEKGHQVHIIDQRD 36 >1GPJ-A nrPDB Length = 404 Score = 31.2 bits (69), Expect = 0.56, Method: Composition-based stats. Identities = 19/56 (33%), Positives = 26/56 (46%), Gaps = 4/56 (7%) Query: 5 TRQFMRSVSSSSTASASAKKII----VKHVTVIGGGLMGAGIAQVAAATGHTVVLV 56 TR +VS S A A++ + K V V+G G MG +A+ G VLV Sbjct: 141 TRISEGAVSIGSAAVELAERELGSLHDKTVLVVGAGEMGKTVAKSLVDRGVRAVLV 196 >6APH-A nrPDB Length = 445 Score = 31.2 bits (69), Expect = 0.58, Method: Composition-based stats. Identities = 13/45 (28%), Positives = 18/45 (40%), Gaps = 1/45 (2%) Query: 28 KHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTE-DILAKSKKGIE 71 K V V G G +G G A G V + + L + +G E Sbjct: 227 KRVVVCGFGDVGKGTAASFRGAGSIVTVTEIDPICALQAAMEGYE 271 >4PLF-A nrPDB Length = 334 Score = 31.2 bits (69), Expect = 0.63, Method: Composition-based stats. Identities = 25/150 (16%), Positives = 49/150 (32%), Gaps = 12/150 (8%) Query: 28 KHVTVIGGGLMGAGIAQVAAATGH-TVVLVDQTE-----DILAKSKKGIEESLRKVAKKK 81 K +++IG G++G +A + A VVL D + L S Sbjct: 9 KKISLIGSGMIGGTMAYLCAQKELGDVVLFDVVKNMPQGKALDLSHSSSIADTNVKVTGT 68 Query: 82 FAENLKAGDEFVEKTLSTIATSTDAASVVHSTDLVVEAIVENLKVKNELFKRLDKFAAEH 141 + G + V T + DL+ N K+ E+ + + K+ Sbjct: 69 NSYEDIKGSDVVIITAGLTKAPGKSDKEWSRDDLL----PFNAKIMREVGENIKKYCPNA 124 Query: 142 -TIFASNTSSLQITSIANATTRQD-RFAGL 169 I +N + + + + + G+ Sbjct: 125 FVIVITNPLDVMVKVLHEHSGLPKNKVCGM 154 >3BHF-A nrPDB Length = 390 Score = 31.2 bits (69), Expect = 0.63, Method: Composition-based stats. Identities = 11/29 (37%), Positives = 13/29 (44%) Query: 30 VTVIGGGLMGAGIAQVAAATGHTVVLVDQ 58 V V+G G MG A G +LVD Sbjct: 7 VIVVGAGSMGMAAGYQLAKQGVKTLLVDA 35 >6IHE-A nrPDB Length = 303 Score = 30.9 bits (68), Expect = 0.70, Method: Composition-based stats. Identities = 22/91 (24%), Positives = 31/91 (34%), Gaps = 20/91 (21%) Query: 29 HVTVIGGGLMGAGIAQVAAATGH--TVVLVDQTEDILAKSKKGIEESLRKVAKKKFAENL 86 V IG G +G IA A +G V+ D ++ K E LR K + Sbjct: 2 KVGFIGAGKIGQTIAYSALVSGAVDEAVIYDIIPELPDK----FEHELRHAFATKGIKAN 57 Query: 87 KAGDEFVEKTLSTIATSTDAASVVHSTDLVV 117 G T++ V D+VV Sbjct: 58 VLG--------------TNSLDDVSGMDIVV 74 >5A9T-A nrPDB Length = 290 Score = 30.9 bits (68), Expect = 0.72, Method: Composition-based stats. Identities = 11/31 (35%), Positives = 17/31 (54%) Query: 30 VTVIGGGLMGAGIAQVAAATGHTVVLVDQTE 60 VTV G G MG+ +A GH V + +++ Sbjct: 8 VTVAGLGPMGSALAAALLDRGHDVTVWNRSP 38 >1PZF-A nrPDB Length = 331 Score = 30.9 bits (68), Expect = 0.74, Method: Composition-based stats. Identities = 28/148 (18%), Positives = 50/148 (33%), Gaps = 12/148 (8%) Query: 28 KHVTVIGGGLMGAGIAQVAAATGHT-VVLVDQTE-----DILAKS-KKGIEESLRKVAKK 80 K V +IG G++G + + A VVL D + L S + ++ V + Sbjct: 10 KKVAMIGSGMIGGTMGYLCALRELADVVLYDVVKGMPEGKALDLSHVTSVVDTNVSVRAE 69 Query: 81 KFAENLKAGDEFVEKTLSTIATSTDAASVVHSTDLVVEAIVENLKVKNELFKRLDKFAAE 140 E G + V T S DL+ N K+ E+ + + K+ + Sbjct: 70 YSYEAALTGADCVIVTAGLTKVPGKPDSEWSRNDLL----PFNSKIIREIGQNIKKYCPK 125 Query: 141 H-TIFASNTSSLQITSIANATTRQDRFA 167 I +N + + A+ Sbjct: 126 TFIIVVTNPLDCMVKVMCEASGVPTNMI 153 >4K22-A nrPDB Length = 365 Score = 30.9 bits (68), Expect = 0.77, Method: Composition-based stats. Identities = 15/71 (21%), Positives = 31/71 (43%), Gaps = 2/71 (2%) Query: 30 VTVIGGGLMGAGIAQVAAATGHTVVLVD--QTEDILAKSKKGIEESLRKVAKKKFAENLK 87 V ++GGG++G +A +G V +++ E + A + + S A +K L Sbjct: 6 VAIVGGGMVGLAVACGLQGSGLRVAVLEQRVQEPLAANAPPQLRVSAINAASEKLLTRLG 65 Query: 88 AGDEFVEKTLS 98 + + + S Sbjct: 66 VWQDILSRRAS 76 >3N58-A nrPDB Length = 464 Score = 30.9 bits (68), Expect = 0.77, Method: Composition-based stats. Identities = 14/45 (31%), Positives = 19/45 (42%), Gaps = 2/45 (4%) Query: 29 HVTVI-GGGLMGAGIAQVAAATGHTVVLVDQTE-DILAKSKKGIE 71 V V+ G G +G G AQ A G V + + L + G E Sbjct: 248 KVAVVCGYGDVGKGSAQSLAGAGARVKVTEVDPICALQAAMDGFE 292 >3L6D-A nrPDB Length = 306 Score = 30.9 bits (68), Expect = 0.78, Method: Composition-based stats. Identities = 12/31 (38%), Positives = 18/31 (58%) Query: 30 VTVIGGGLMGAGIAQVAAATGHTVVLVDQTE 60 V+VIG G MG +AQV G V + +++ Sbjct: 12 VSVIGLGAMGTIMAQVLLKQGKRVAIWNRSP 42 >3G79-A nrPDB Length = 478 Score = 30.9 bits (68), Expect = 0.84, Method: Composition-based stats. Identities = 33/184 (17%), Positives = 71/184 (38%), Gaps = 25/184 (13%) Query: 23 KKIIVKHVTVIGGGLMGAGIAQVAA----------------ATGHTVVLVDQTEDILAKS 66 ++ +K + V+G G +G A + A ++G+ + ++++ E L Sbjct: 14 ERGPIKKIGVLGMGYVGIPAAVLFADAPCFEKVLGFQRNSKSSGYKIEMLNRGESPLKGE 73 Query: 67 KKGIEESLRKVAKK---KFAENLKAGDEFVEKTLSTIATSTDAASVVHSTDLVVEAIVEN 123 + G+EE + KV K + + E TL+ + + +++ I N Sbjct: 74 EPGLEELIGKVVKAGKFECTPDFSRISELDAVTLAIQTPFANPKDLEPDFSALIDGI-RN 132 Query: 124 LK--VKNELFKRLDKFAAEHTIFASNTSSLQITSIANATTRQDRFAGLHFFNPVPVMKLV 181 + +K + L+ T + + QI + + FA H V V +L+ Sbjct: 133 VGKYLKPGMLVVLESTITPGT---TEGMAKQILEEESGLKAGEDFALAHAPERVMVGRLL 189 Query: 182 EVIK 185 + I+ Sbjct: 190 KNIR 193 >3QHA-A nrPDB Length = 296 Score = 30.9 bits (68), Expect = 0.85, Method: Composition-based stats. Identities = 42/290 (14%), Positives = 85/290 (29%), Gaps = 60/290 (20%) Query: 15 SSTASASAKKIIVKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESL 74 S + +A + IG G MGA +A V + D + + Sbjct: 3 GSMTTNAAHTTEQLKLGYIGLGNMGAPMATRMTEWPGGVTVYDIRIEA-----------M 51 Query: 75 RKVAKKKFAENLKAGDEFVEKTLSTIATSTDAASVVHSTDLVVEAIVENLKVKNELFKRL 134 +A+ A + + L I DA E+ L Sbjct: 52 TPLAEAG-ATLADSVADVAAADLIHITVLDDAQV-------------------REVVGEL 91 Query: 135 DKFAAEHTIFASNTSSLQITSIANATTRQDRFAGLHFFNPVPVMKLVEVIKTPM-----T 189 A T+ A + S++ + A R + +H + + + Sbjct: 92 AGHAKPGTVIAIH-STIS-DTTAVELARDLKARDIHIVDAPVSGGAAAAARGELATMVGA 149 Query: 190 SQKTFESLVDFSKALGKHPVSCKDTPGFIVNRL----------LVPYLMEAIRLYERGDA 239 ++ +E + K + + PG R+ EA++L E Sbjct: 150 DREVYERIKPAFKHWAAVVIHAGE-PG-AGTRMKLARNMLTFTSYAAACEAMKLAEAAGL 207 Query: 240 SKEDIDTAMKLGAGYPMGPFELLDYVGLDTTKFIVDGWHEMDAENPLHQP 289 + + ++ GP ++ + D +++ +N L+QP Sbjct: 208 DLQALGRVVRHTDALTGGPGAIM----------VRDNMKDLEPDNFLYQP 247 >6FQY-A nrPDB Length = 468 Score = 30.5 bits (67), Expect = 0.91, Method: Composition-based stats. Identities = 14/83 (16%), Positives = 33/83 (39%) Query: 30 VTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKKFAENLKAG 89 + +IG +MG ++ ++ G + + ++T + ++ K +E V K E L Sbjct: 4 IGLIGLAVMGQNLSLNISSKGFKIGVYNRTYERTEETMKRAKEENLVVYGYKTVEELINN 63 Query: 90 DEFVEKTLSTIATSTDAASVVHS 112 + K + I + + Sbjct: 64 LKKPRKVILLIKAGPAVDENISN 86 >5T5Q-A nrPDB Length = 247 Score = 30.5 bits (67), Expect = 0.94, Method: Composition-based stats. Identities = 15/78 (19%), Positives = 29/78 (37%), Gaps = 1/78 (1%) Query: 28 KHVTVIGG-GLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKKFAENL 86 + + + G G +G IA++ A+G +VL D + L + R K A + Sbjct: 10 RTLVLTGANGGIGRAIAELFHASGANLVLTDLDREGLDAFAASLGSPERIATIKADASSA 69 Query: 87 KAGDEFVEKTLSTIATST 104 ++ V + Sbjct: 70 DDAEKTVALAMERFGGID 87 >6GGU-A nrPDB Length = 344 Score = 30.5 bits (67), Expect = 0.96, Method: Composition-based stats. Identities = 24/159 (15%), Positives = 52/159 (32%), Gaps = 14/159 (8%) Query: 55 LVDQTEDILAKSKKGIEESLRKVAKKKFAENLKAGDEFVEKTLSTIATSTDAASVVHSTD 114 +++ ++ K I E + +VAK+ A + L +TD V D Sbjct: 81 VIEAHKEDPEKIMPQIREKVNEVAKELPKPPEGAIHFTHPEDLG-FEITTDDREAVADAD 139 Query: 115 LVVEAIVENLKVKNELFKRLDKFAAEHTIFASNTSSLQITSIANA--------TTRQD-- 164 ++ + ++ ++ + I ++ ++ T T+ + Sbjct: 140 FIMTWFPKG-DMQPDIINKFIDDIKPGAIV-THACTIPTTKFYKIFEQKHGDLVTKPETL 197 Query: 165 RFAGLHFFNPVPVMKLVEVIKTPMTSQKTFESLVDFSKA 203 H VP MK I S+ E+L + + Sbjct: 198 NVTSYHP-GAVPEMKGQVYIAEGYASEDAIETLFELGQK 235 >5O3Z-A nrPDB Length = 263 Score = 30.5 bits (67), Expect = 0.99, Method: Composition-based stats. Identities = 18/79 (22%), Positives = 33/79 (41%), Gaps = 4/79 (5%) Query: 23 KKIIVKHVTVI--GGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKK 80 + ++ V V+ GG +GA + + A G+ V + D E + I R A + Sbjct: 1 GAMAMEQVAVVIGGGQTLGAFLCEGLAQAGYHVAVADLNESNANRLADTINS--RYGAGR 58 Query: 81 KFAENLKAGDEFVEKTLST 99 + + A DE + L+ Sbjct: 59 AYGFKVDATDEASVEALAR 77 >5J7X-A nrPDB Length = 549 Score = 30.5 bits (67), Expect = 1.1, Method: Composition-based stats. Identities = 23/112 (20%), Positives = 41/112 (36%), Gaps = 5/112 (4%) Query: 14 SSSTASASAKKIIVKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDI-LAKSKKGIEE 72 S+ A + K V VIG G G I Q A L +T ++ L ++ + Sbjct: 170 SAHWPEAEEISVKGKKVAVIGTGSTGIQIFQEWAREAEEAFLFQRTPNLCLPMRQQELHA 229 Query: 73 SLRKVAKKKFAENLKAGDEFVEKTLSTIATSTDAASVVHSTDLVVEAIVENL 124 + K ++A+ L T + + +++ EA E+L Sbjct: 230 GYQVKDKGEYADYLAE----CALTFGGLEYQQTPKNTFDASEEEREAFWEDL 277 >2P4Q-A nrPDB Length = 497 Score = 30.1 bits (66), Expect = 1.2, Method: Composition-based stats. Identities = 20/91 (21%), Positives = 33/91 (36%), Gaps = 8/91 (8%) Query: 31 TVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKKFAENLKAGD 90 +IG +MG + AA G TV ++T+ + L AK K + + Sbjct: 14 GLIGLAVMGQNLILNAADHGFTVCAYNRTQSKVD-------HFLANEAKGKSIIGATSIE 66 Query: 91 EFVEKTLSTIATSTDAASVVHSTDLVVEAIV 121 +F+ K L D ++ IV Sbjct: 67 DFISK-LKRPRKVMLLVKAGAPVDALINQIV 96 >1ZOV-A nrPDB Length = 386 Score = 30.1 bits (66), Expect = 1.2, Method: Composition-based stats. Identities = 11/29 (37%), Positives = 13/29 (44%) Query: 30 VTVIGGGLMGAGIAQVAAATGHTVVLVDQ 58 V V+G G MG A G +LVD Sbjct: 6 VIVVGAGSMGMAAGYYLAKQGVKTLLVDS 34 >3IHG-A nrPDB Length = 535 Score = 30.1 bits (66), Expect = 1.2, Method: Composition-based stats. Identities = 11/31 (35%), Positives = 16/31 (51%) Query: 30 VTVIGGGLMGAGIAQVAAATGHTVVLVDQTE 60 V V+G GL G A A G V++V++ Sbjct: 8 VLVVGAGLGGLSTAMFLARQGVRVLVVERRP 38 >5G6R-A nrPDB Length = 295 Score = 30.1 bits (66), Expect = 1.2, Method: Composition-based stats. Identities = 9/34 (26%), Positives = 16/34 (47%) Query: 28 KHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTED 61 KH+ + G G MG +A G+ + ++T Sbjct: 3 KHIGIFGLGAMGTALAAKYLEHGYKTSVWNRTTA 36 >3ICS-A nrPDB Length = 588 Score = 30.1 bits (66), Expect = 1.2, Method: Composition-based stats. Identities = 12/37 (32%), Positives = 19/37 (51%) Query: 28 KHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILA 64 +H TVIGGG +G + + G V LV+ ++ Sbjct: 188 RHATVIGGGFIGVEMVENLRERGIEVTLVEMANQVMP 224 >1X0X-A nrPDB Length = 354 Score = 30.1 bits (66), Expect = 1.3, Method: Composition-based stats. Identities = 14/96 (14%), Positives = 31/96 (32%), Gaps = 7/96 (7%) Query: 28 KHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESL--RKVAKKKFAEN 85 K V ++G G G+ IA++ + D EE + +K+ + ++ Sbjct: 9 KKVCIVGSGNWGSAIAKIVGGNAAQLAQFDPRVT-----MWVFEEDIGGKKLTEIINTQH 63 Query: 86 LKAGDEFVEKTLSTIATSTDAASVVHSTDLVVEAIV 121 K + D D+++ + Sbjct: 64 ENVKYLPGHKLPPNVVAVPDVVQAAEDADILIFVVP 99 >5VDN-A nrPDB Length = 463 Score = 30.1 bits (66), Expect = 1.3, Method: Composition-based stats. Identities = 28/152 (18%), Positives = 52/152 (34%), Gaps = 17/152 (11%) Query: 28 KHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKKFAENLK 87 K V V+G G + IA V G L + L I E+L +V + + Sbjct: 181 KRVAVVGAGYIAVEIAGVLNGLGTETHLFVRKHAPLRTFDPLIVETLLEVMNTEGPKLHT 240 Query: 88 AGDEFVEKTLSTIATSTDAASVVH-STDLVV-----EAIVENLKVKN-------ELFKRL 134 + + + + + D ++ E +NL + + + + Sbjct: 241 ESVPKAVIKNADGSLTLQLENGTEVTVDHLIWAIGREPATDNLNLSVTGVKTNDKGYIEV 300 Query: 135 DKFAAEHT----IFASNTSSLQITSIANATTR 162 DKF + NT +++T +A A R Sbjct: 301 DKFQNTNVKGIYAVGDNTGVVELTPVAVAAGR 332 >3DO5-A nrPDB Length = 327 Score = 30.1 bits (66), Expect = 1.3, Method: Composition-based stats. Identities = 17/122 (13%), Positives = 44/122 (36%), Gaps = 13/122 (10%) Query: 29 HVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKKFAENLKA 88 + ++G G +G G+A++ + + K+ + + +K + + Sbjct: 4 KIAIVGFGTVGQGVAELLIR----------KREEIEKAIGEFKVTAVADSKSSISGDFSL 53 Query: 89 GD-EFVEKTLSTIATSTDAASVVHST--DLVVEAIVENLKVKNELFKRLDKFAAEHTIFA 145 + +++ + A VV S D+++EA V + + + + Sbjct: 54 VEALRMKRETGMLRDDAKAIEVVRSADYDVLIEASVTRVDGGEGVNYIREALKRGKHVVT 113 Query: 146 SN 147 SN Sbjct: 114 SN 115 >3OC4-A nrPDB Length = 452 Score = 30.1 bits (66), Expect = 1.3, Method: Composition-based stats. Identities = 41/239 (17%), Positives = 83/239 (34%), Gaps = 28/239 (11%) Query: 28 KHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAK--SKKGIEESLRKVAKKKFAEN 85 + V VIG G +G TV + + E++L K K+ + E + + K+ + Sbjct: 148 QTVAVIGAGPIGMEAIDFLVKMKKTVHVFESLENLLPKYFDKEMVAEVQKSLEKQAVIFH 207 Query: 86 LKAGDEFVEKTLSTIATSTDAASVVHSTDLVVEAI---VENLKVKNELFKRLDKFAAEHT 142 + +E+T + I T + S D + A+ + + ++ + LD+ A Sbjct: 208 FEETVLGIEETANGIVLETSEQEI--SCDSGIFALNLHPQLAYLDKKIQRNLDQTIAVDA 265 Query: 143 IFASNTSSLQITSIANATTRQDRFAGLHFFNPVPVMKLVEVIKTPMTSQKTFESLVDFSK 202 TS + +I + + + F+ P+ V V + + E F Sbjct: 266 YL--QTSVPNVFAIGDCISVMNEPVAETFYAPL-VNNAVR--TGLVVANNLEEKTHRFIG 320 Query: 203 ALGKHPVSCKDTPGFIVNRLLVPYLMEAIRLYE-RGDASKEDIDTAMKLGAGYPMGPFE 260 +L D Y + + L E G + + + + P P + Sbjct: 321 SLRTMGTKVGD------------YYLASTGLTETEGLFFPQTLASIIVRQ---PAPPLQ 364 >2HQM-A nrPDB Length = 479 Score = 30.1 bits (66), Expect = 1.3, Method: Composition-based stats. Identities = 22/93 (23%), Positives = 39/93 (41%), Gaps = 3/93 (3%) Query: 28 KHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKKFAENLK 87 K V V+G G +G +A V G LV + E +L K + I+ ++ K+ K Sbjct: 186 KKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGINVHK 245 Query: 88 AGDE-FVEKTLST--IATSTDAASVVHSTDLVV 117 VEK + T + + + + D ++ Sbjct: 246 LSKIVKVEKNVETDKLKIHMNDSKSIDDVDELI 278 >1X14-A nrPDB Length = 401 Score = 30.1 bits (66), Expect = 1.4, Method: Composition-based stats. Identities = 19/97 (19%), Positives = 34/97 (35%), Gaps = 2/97 (2%) Query: 21 SAKKIIVKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKK 80 +A K+ V VIG G+ G A + G V D ++ + + E L K+ Sbjct: 166 AAGKVPPAKVMVIGAGVAGLAAIGAANSLGAIVRAFDTRPEVKEQVQSMGAEFLELDFKE 225 Query: 81 KFAENLKAGDEFVEKTLSTIATSTDAASVVHSTDLVV 117 + + + A A+ D++V Sbjct: 226 EAGSGDGYAKVMSDAFIK--AEMELFAAQAKEVDIIV 260 >4EMJ-A nrPDB Length = 410 Score = 30.1 bits (66), Expect = 1.4, Method: Composition-based stats. Identities = 10/42 (23%), Positives = 23/42 (54%) Query: 28 KHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKG 69 + ++GGGL+G +A A G +V +++ +++L + Sbjct: 144 TRLLIVGGGLIGCEVATTARKLGLSVTILEAGDELLVRVLGR 185 >1LSS-A nrPDB Length = 140 Score = 30.1 bits (66), Expect = 1.5, Method: Composition-based stats. Identities = 17/65 (26%), Positives = 30/65 (46%) Query: 30 VTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKKFAENLKAG 89 + + G G +G +A+ + GH +VL+D +DI K+ I+ + K AG Sbjct: 7 IIIAGIGRVGYTLAKSLSEKGHDIVLIDIDKDICKKASAEIDALVINGDCTKIKTLEDAG 66 Query: 90 DEFVE 94 E + Sbjct: 67 IEDAD 71 >3VH2-A nrPDB Length = 616 Score = 29.7 bits (65), Expect = 1.6, Method: Composition-based stats. Identities = 25/117 (21%), Positives = 44/117 (37%), Gaps = 8/117 (6%) Query: 28 KHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKKFAENLK 87 V ++G G +G +++ A G + + +R+ A F + K Sbjct: 328 TKVLLLGAGTLGCYVSRALIAWGVRKI------TFVDNGTVSYSNPVRQ-ALYNFEDCGK 380 Query: 88 AGDEFVEKTLSTIATSTDAASVVHSTDLVVEAIVENLKVKNELFKRLDKFAAEHTIF 144 E +L I DA V S ++ +V N + +++ F RL EH I Sbjct: 381 PKAELAAASLKRIFPLMDATGVKLSIPMIGHKLV-NEEAQHKDFDRLRALIKEHDII 436 >3T7E-A nrPDB Length = 344 Score = 29.7 bits (65), Expect = 1.6, Method: Composition-based stats. Identities = 25/117 (21%), Positives = 44/117 (37%), Gaps = 8/117 (6%) Query: 28 KHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKKFAENLK 87 V ++G G +G +++ A G + + +R+ A F + K Sbjct: 39 TKVLLLGAGTLGCYVSRALIAWGVRKI------TFVDNGTVSYSNPVRQ-ALYNFEDCGK 91 Query: 88 AGDEFVEKTLSTIATSTDAASVVHSTDLVVEAIVENLKVKNELFKRLDKFAAEHTIF 144 E +L I DA V S ++ +V N + +++ F RL EH I Sbjct: 92 PKAELAAASLKRIFPLMDATGVKLSIPMIGHKLV-NEEAQHKDFDRLRALIKEHDII 147 >3CKY-A nrPDB Length = 301 Score = 29.7 bits (65), Expect = 1.7, Method: Composition-based stats. Identities = 11/32 (34%), Positives = 13/32 (40%) Query: 29 HVTVIGGGLMGAGIAQVAAATGHTVVLVDQTE 60 + IG G MG +A G TV D E Sbjct: 6 KIGFIGLGAMGKPMAINLLKEGVTVYAFDLME 37 >2RIR-A nrPDB Length = 300 Score = 29.7 bits (65), Expect = 1.7, Method: Composition-based stats. Identities = 13/38 (34%), Positives = 19/38 (50%) Query: 28 KHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAK 65 V V+G G G IA+ AA G V + ++ LA+ Sbjct: 158 SQVAVLGLGRTGMTIARTFAALGANVKVGARSSAHLAR 195 >5W4C-A nrPDB Length = 371 Score = 29.7 bits (65), Expect = 1.7, Method: Composition-based stats. Identities = 10/40 (25%), Positives = 14/40 (35%) Query: 18 ASASAKKIIVKHVTVIGGGLMGAGIAQVAAATGHTVVLVD 57 + K + V +IG G G A A VL + Sbjct: 21 RTGEVSKKMHSKVVIIGSGPGGHTAAIYLARANLEPVLYE 60 >4D3S-A nrPDB Length = 293 Score = 29.7 bits (65), Expect = 1.7, Method: Composition-based stats. Identities = 12/71 (16%), Positives = 24/71 (33%) Query: 30 VTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKKFAENLKAG 89 VT+IG G MG +A G+ + + ++T+ + A+ A Sbjct: 11 VTLIGLGPMGQAMAGALLEAGYELTVWNRTKAKAEALAERGAAVADSPAEALRAGGPVLL 70 Query: 90 DEFVEKTLSTI 100 + + Sbjct: 71 SLTEHAVMYRV 81 >4IV9-A nrPDB Length = 557 Score = 29.7 bits (65), Expect = 1.8, Method: Composition-based stats. Identities = 12/69 (17%), Positives = 25/69 (36%), Gaps = 1/69 (1%) Query: 8 FMRSVSSSSTASASAKKIIVKHVTVIGGGLMGAGIAQVAAATGHT-VVLVDQTEDILAKS 66 F++ + + + V ++G G+ G A G VVL + + I + Sbjct: 19 FLKKCEMTGGIGSYSAGTPTPRVAIVGAGISGLVAATELLRAGVKDVVLYESRDRIGGRV 78 Query: 67 KKGIEESLR 75 + + R Sbjct: 79 WSQVFDQTR 87 >1J49-A nrPDB Length = 333 Score = 29.7 bits (65), Expect = 1.8, Method: Composition-based stats. Identities = 19/104 (18%), Positives = 39/104 (37%), Gaps = 5/104 (4%) Query: 17 TASASAKKIIVKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRK 76 A +++ + V V+G G +G Q+ G V+ D + + K +SL Sbjct: 136 WAPTIGREVRDQVVGVVGTGHIGQVFMQIMEGFGAKVITYDIFRNPELEKKGYYVDSLDD 195 Query: 77 VAKKKFAENLKAGDEFVEKTLSTIATSTDAASVVHSTDLVVEAI 120 + K+ +L D + + D + D+V+ + Sbjct: 196 LYKQADVISLHVPDVP-----ANVHMINDESIAKMKQDVVIVNV 234 >5EVY-X nrPDB Length = 438 Score = 29.7 bits (65), Expect = 1.8, Method: Composition-based stats. Identities = 14/69 (20%), Positives = 24/69 (34%), Gaps = 2/69 (2%) Query: 29 HVTVIGGGLMGAGIAQVAAATGH-TVVLVDQTEDILAKSKKGIEESLRKVAKKKFAENLK 87 V VIGGG+ G +A + + H V L + G+ + V + + Sbjct: 24 RVAVIGGGIAGTALALGLSKSSHVNVKLFETAPAFGEIG-AGVSFGVNAVEAIQRLGIGE 82 Query: 88 AGDEFVEKT 96 + T Sbjct: 83 LYKSVADST 91 >1OOE-A nrPDB Length = 236 Score = 29.7 bits (65), Expect = 1.8, Method: Composition-based stats. Identities = 18/97 (18%), Positives = 37/97 (38%), Gaps = 8/97 (8%) Query: 29 HVTVIGG-GLMGAGIAQVAAATGHTVVLVDQTED-------ILAKSKKGIEESLRKVAKK 80 V V GG G +G+ I + G+TV+ +D + + ++ +K E+ + + Sbjct: 5 KVIVYGGKGALGSAILEFFKKNGYTVLNIDLSANDQADSNILVDGNKNWTEQEQSILEQT 64 Query: 81 KFAENLKAGDEFVEKTLSTIATSTDAASVVHSTDLVV 117 + D S + V + DL++ Sbjct: 65 ASSLQGSQVDGVFCVAGGWAGGSASSKDFVKNADLMI 101 >5NMX-A nrPDB Length = 425 Score = 29.7 bits (65), Expect = 1.9, Method: Composition-based stats. Identities = 8/32 (25%), Positives = 16/32 (50%) Query: 27 VKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQ 58 ++ V V+G G G A+ G V++ ++ Sbjct: 1 MRRVAVLGAGPSGLTAARYLKQAGFEVMVFER 32 >3FR8-A nrPDB Length = 525 Score = 29.7 bits (65), Expect = 1.9, Method: Composition-based stats. Identities = 26/141 (18%), Positives = 48/141 (34%), Gaps = 22/141 (15%) Query: 27 VKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKKFAENL 86 +K + VIG G G AQ D LA++K I V K + Sbjct: 54 IKQIGVIGWGSQGPAQAQNL-------------RDSLAEAKSDI------VVKIGLRKGS 94 Query: 87 KAGDEFVEKTLSTIATST-DAASVVHSTDLVVEAIVENLKVKNELFKRLDKFAAEHTIFA 145 K+ DE + + + D V +DLV+ I + + + ++++ ++I Sbjct: 95 KSFDEARAAGFTEESGTLGDIWETVSGSDLVLLLISD--AAQADNYEKIFSHMKPNSILG 152 Query: 146 SNTSSLQITSIANATTRQDRF 166 + L + Sbjct: 153 LSHGFLLGHLQSAGLDFPKNI 173 >5MIU-A nrPDB Length = 535 Score = 29.3 bits (64), Expect = 2.0, Method: Composition-based stats. Identities = 21/100 (21%), Positives = 39/100 (39%), Gaps = 7/100 (7%) Query: 27 VKHVTVIGGGLMGAGIAQVAAA----TGHTVVLVDQTEDILAKSKKGIEES--LRKVAKK 80 VK +TVIG G +G+ +A +G V+ + + + K + + KV ++ Sbjct: 222 VKSITVIGEGFLGSELACALGRKSQASGIEVIQLFPEKGNMGKILPQYLSNWTMEKVKRE 281 Query: 81 KFAENLKAGDEFVEKTLSTIATSTDAASVVHSTDLVVEAI 120 A + V + + V TD +V A+ Sbjct: 282 GVKVMPNAIVQSVGVSGGRLLIKLKDGRKVE-TDHIVTAV 320 >3ENK-A nrPDB Length = 341 Score = 29.3 bits (64), Expect = 2.0, Method: Composition-based stats. Identities = 18/67 (26%), Positives = 27/67 (40%), Gaps = 6/67 (8%) Query: 34 GGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKKFAENLKAGDEFV 93 G G +G+ A A G+ VV+ D L SK+ + K+ K D Sbjct: 13 GAGYIGSHTAVELLAHGYDVVIADN----LVNSKREAIARIEKITGK--TPAFHETDVSD 66 Query: 94 EKTLSTI 100 E+ L+ I Sbjct: 67 ERALARI 73 >5YEQ-A nrPDB Length = 340 Score = 29.3 bits (64), Expect = 2.1, Method: Composition-based stats. Identities = 9/26 (34%), Positives = 11/26 (42%) Query: 28 KHVTVIGGGLMGAGIAQVAAATGHTV 53 K V V+G G G A +G V Sbjct: 18 KRVAVLGYGSQGRAWALNLRDSGIKV 43 >5FLX-A nrPDB Length = 295 Score = 29.3 bits (64), Expect = 2.1, Method: Composition-based stats. Identities = 17/75 (22%), Positives = 32/75 (42%), Gaps = 7/75 (9%) Query: 173 NPVPVMKLVEVIKTPMTSQKTFESLVDFSKALGKHPVSCKDTPGFIVNRLLVPYLMEAIR 232 NP V VI + T Q+ ++ F+ A G P++ + TPG N++ + + Sbjct: 70 NPAD----VSVISSRNTGQRA---VLKFAAATGATPIAGRFTPGTFTNQIQAAFREPRLL 122 Query: 233 LYERGDASKEDIDTA 247 + A + + A Sbjct: 123 VVTDPRADHQPLTEA 137 >4UJC-CA nrPDB Length = 263 Score = 29.3 bits (64), Expect = 2.1, Method: Composition-based stats. Identities = 17/75 (22%), Positives = 32/75 (42%), Gaps = 7/75 (9%) Query: 173 NPVPVMKLVEVIKTPMTSQKTFESLVDFSKALGKHPVSCKDTPGFIVNRLLVPYLMEAIR 232 NP V VI + T Q+ ++ F+ A G P++ + TPG N++ + + Sbjct: 70 NPAD----VSVISSRNTGQRA---VLKFAAATGATPIAGRFTPGTFTNQIQAAFREPRLL 122 Query: 233 LYERGDASKEDIDTA 247 + A + + A Sbjct: 123 VVTDPRADHQPLTEA 137 >3BCH-A nrPDB Length = 253 Score = 29.3 bits (64), Expect = 2.1, Method: Composition-based stats. Identities = 17/75 (22%), Positives = 32/75 (42%), Gaps = 7/75 (9%) Query: 173 NPVPVMKLVEVIKTPMTSQKTFESLVDFSKALGKHPVSCKDTPGFIVNRLLVPYLMEAIR 232 NP V VI + T Q+ ++ F+ A G P++ + TPG N++ + + Sbjct: 103 NPAD----VSVISSRNTGQRA---VLKFAAATGATPIAGRFTPGTFTNQIQAAFREPRLL 155 Query: 233 LYERGDASKEDIDTA 247 + A + + A Sbjct: 156 VVTDPRADHQPLTEA 170 >1UZM-A nrPDB Length = 247 Score = 29.3 bits (64), Expect = 2.2, Method: Composition-based stats. Identities = 17/43 (39%), Positives = 23/43 (53%), Gaps = 2/43 (4%) Query: 15 SSTASASAKKIIVKHVTVIGGGLMGAG--IAQVAAATGHTVVL 55 ++TA+ AK V ++ GG G G IAQ AA GH V + Sbjct: 2 TATATEGAKPPFVSRSVLVTGGNRGIGLAIAQRLAADGHKVAV 44 >3I83-A nrPDB Length = 320 Score = 29.3 bits (64), Expect = 2.3, Method: Composition-based stats. Identities = 19/88 (21%), Positives = 34/88 (38%), Gaps = 3/88 (3%) Query: 29 HVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKKFAENLKA 88 ++ VIG G +G+ + A TGH V +V +++ K+K +R + A Sbjct: 4 NILVIGTGAIGSFYGALLAKTGHCVSVVSRSDYETVKAKGI---RIRSATLGDYTFRPAA 60 Query: 89 GDEFVEKTLSTIATSTDAASVVHSTDLV 116 + + + VV D V Sbjct: 61 VVRSAAELETKPDCTLLCIKVVEGADRV 88 >3WTC-A nrPDB Length = 262 Score = 29.3 bits (64), Expect = 2.3, Method: Composition-based stats. Identities = 19/75 (25%), Positives = 32/75 (42%), Gaps = 5/75 (6%) Query: 31 TVIGGGL-MGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIE----ESLRKVAKKKFAEN 85 V G +G IA A G V+L+D +D LA++ K +E ++ A + Sbjct: 12 AVTGAAQGIGKAIALRLAKDGADVILLDVKQDTLAETAKEVEALGRRAVALTADISNRDQ 71 Query: 86 LKAGDEFVEKTLSTI 100 ++ KTL + Sbjct: 72 FRSTLADAAKTLGGL 86 >5XVH-A nrPDB Length = 306 Score = 29.3 bits (64), Expect = 2.4, Method: Composition-based stats. Identities = 20/92 (21%), Positives = 36/92 (39%), Gaps = 9/92 (9%) Query: 29 HVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKKFAENLKA 88 V IG G+MG +A G + ++T + K+K E + AE+ Sbjct: 22 RVGFIGLGIMGGPMATHLLKAGFLAAVYNRTRE---KTKPFAEAGVY------VAESPAD 72 Query: 89 GDEFVEKTLSTIATSTDAASVVHSTDLVVEAI 120 + V+ + ++ + D V+ VVE Sbjct: 73 LAKRVDVVIVMVSDAPDVEQVLFGPSGVVEGA 104 >3GVH-A nrPDB Length = 324 Score = 29.3 bits (64), Expect = 2.4, Method: Composition-based stats. Identities = 27/146 (18%), Positives = 48/146 (32%), Gaps = 9/146 (6%) Query: 28 KHVTVIGGGLMGAGIAQVAAATGH-TVVLVDQTE-DILAKSKKGIEESLRKVAKKKFAEN 85 + +IG G++G +A +A VVL D E K E S KF Sbjct: 8 NKIALIGSGMIGGTLAHLAGLKELGDVVLFDIAEGTPQGKGLDIAESSPVDGFDAKFTGA 67 Query: 86 LKAGDEFVEKTLSTIATSTDAASVVHSTDLVVEAIVENLKVKNELFKRLDKFAAEHTIFA 145 + A + L + NLKV ++ + K+A E + Sbjct: 68 NDYAAIEGADVVIVTAGVPRKPGMSRDDLLGI-----NLKVMEQVGAGIKKYAPEAFVIC 122 Query: 146 -SNTSSLQITSIANATTRQ-DRFAGL 169 +N + ++ + + G+ Sbjct: 123 ITNPLDAMVWALQKFSGLPAHKVVGM 148 >4MOP-A nrPDB Length = 633 Score = 29.3 bits (64), Expect = 2.4, Method: Composition-based stats. Identities = 10/40 (25%), Positives = 17/40 (42%), Gaps = 2/40 (5%) Query: 30 VTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKG 69 V ++G G +G A+ G+ V + D E + K Sbjct: 49 VVIVGSGPIGCTYARELVGAGYKVAMFDIGE--IDSGLKI 86 >4WEQ-A nrPDB Length = 341 Score = 29.3 bits (64), Expect = 2.4, Method: Composition-based stats. Identities = 10/48 (20%), Positives = 22/48 (45%) Query: 17 TASASAKKIIVKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILA 64 S + V ++G G++G A+ AA G V+ +++ ++ Sbjct: 151 WRDLSQPEAADVTVGIMGMGVLGQDAARKLAAMGFKVIGWSRSKRVIE 198 >4RQU-A nrPDB Length = 375 Score = 29.3 bits (64), Expect = 2.4, Method: Composition-based stats. Identities = 13/48 (27%), Positives = 22/48 (45%), Gaps = 1/48 (2%) Query: 22 AKKIIVKHVTVIGGGLMGAGIAQVAAATGH-TVVLVDQTEDILAKSKK 68 AK + V + G G +G G A+ A G ++ VD ++K+ Sbjct: 186 AKPKKGQSVAIFGLGAVGLGAAEGARIAGASRIIGVDFNSKRFDQAKE 233 >2HJR-A nrPDB Length = 328 Score = 29.3 bits (64), Expect = 2.5, Method: Composition-based stats. Identities = 11/37 (29%), Positives = 19/37 (51%), Gaps = 1/37 (2%) Query: 25 IIVKHVTVIGGGLMGAGIAQVAAATGH-TVVLVDQTE 60 I+ K +++IG G +G+ IA + V + D E Sbjct: 12 IMRKKISIIGAGQIGSTIALLLGQKDLGDVYMFDIIE 48 >2ZYA-A nrPDB Length = 480 Score = 29.3 bits (64), Expect = 2.5, Method: Composition-based stats. Identities = 8/34 (23%), Positives = 20/34 (58%) Query: 28 KHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTED 61 + + V+G +MG +A + G+TV + +++ + Sbjct: 16 QQIGVVGMAVMGRNLALNIESRGYTVSIFNRSRE 49 >3L76-A nrPDB Length = 600 Score = 28.9 bits (63), Expect = 2.6, Method: Composition-based stats. Identities = 19/133 (14%), Positives = 47/133 (35%), Gaps = 6/133 (4%) Query: 9 MRSVSSSSTASASAKKIIVKHVTVIGGGLMGA-GIAQ----VAAATGHTVVLVDQTEDIL 63 +RS + + + + + + G G++G GIA A G + ++ +E + Sbjct: 337 LRSYPEADQEAEIIVEKGIAKIAIAGAGMIGRPGIAAKMFKTLADVGVNIEMISTSEVKV 396 Query: 64 AKSKKGIEESLRKVAKKKFAENLKAGDEFVEKTLSTIATSTDAASVVHSTDLVVEAIVEN 123 + ++ R +A A + + S + A + + + + Sbjct: 397 SCVIDQ-RDADRAIAALSNAFGVTLSPPKNQTDTSHLPAVRGVALDQDQAQIAIRHVPDR 455 Query: 124 LKVKNELFKRLDK 136 + +LF L + Sbjct: 456 PGMAAQLFTALAE 468 >5INT-A nrPDB Length = 220 Score = 28.9 bits (63), Expect = 2.6, Method: Composition-based stats. Identities = 26/152 (17%), Positives = 46/152 (30%), Gaps = 11/152 (7%) Query: 19 SASAKKIIVKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRK-- 76 K V+ +T G MG IA+VA G V+LV L + Sbjct: 15 PTREKIDPVRFMTNFSSGKMGYAIAEVAVNLGAEVILV-SGPTALNPPLHVTTVQVESAQ 73 Query: 77 ---VAKKKFAENLKAGDEFVEKTLSTIATSTDAASVVHSTDLVVEAIVENLKVKNELFKR 133 A + +N+ + D + D V+E L+ ++ K Sbjct: 74 DMLEAVIQHYQNVDVVIKTAAVADYRPKYVHDNKMKKKNGDAVIE-----LERTVDILKT 128 Query: 134 LDKFAAEHTIFASNTSSLQITSIANATTRQDR 165 L + + + + + A R+ Sbjct: 129 LGEMKDKQLLIGFAAETTNVEEYATKKLREKN 160 >5VVW-A nrPDB Length = 315 Score = 28.9 bits (63), Expect = 2.8, Method: Composition-based stats. Identities = 25/139 (17%), Positives = 47/139 (33%), Gaps = 10/139 (7%) Query: 30 VTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKKFAENLKAG 89 V + G G+ G IA+V G+ V D + E L K + F + Sbjct: 14 VGIGGAGMCG--IAEVLLNLGYEVSGSDLKASA-------VTERLEKFGAQIFIGHQAEN 64 Query: 90 DEFVEKTLSTIATSTDAASVVHSTDLVVEAIVENLKVKNELFKRLDKFAAEHTIFASNTS 149 + + + + A + V + + + + ++ EL + A T + T+ Sbjct: 65 ADGADVLVVSSAINRANPEVASALERRIPVVP-RAEMLAELMRYRHGIAVAGTHGKTTTT 123 Query: 150 SLQITSIANATTRQDRFAG 168 SL + A G Sbjct: 124 SLIASVFAAGGLDPTFVIG 142 >6JCV-A nrPDB Length = 333 Score = 28.9 bits (63), Expect = 2.8, Method: Composition-based stats. Identities = 12/50 (24%), Positives = 21/50 (42%) Query: 20 ASAKKIIVKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKG 69 A+ + K + VIG G G A + G V++ + + +KK Sbjct: 8 ANLDPLKGKTIGVIGYGNQGRVQATIMRENGLNVIVGNVKDKYYELAKKE 57 >3G1U-A nrPDB Length = 437 Score = 28.9 bits (63), Expect = 2.8, Method: Composition-based stats. Identities = 15/48 (31%), Positives = 22/48 (45%), Gaps = 1/48 (2%) Query: 28 KHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTE-DILAKSKKGIEESL 74 K V G G +G G A A G VV+ + + L S +G + +L Sbjct: 213 KTCCVCGYGDVGKGCAAALRAFGARVVVTEVDPINALQASMEGYQVAL 260 >4IZO-A nrPDB Length = 419 Score = 28.9 bits (63), Expect = 2.9, Method: Composition-based stats. Identities = 16/77 (20%), Positives = 28/77 (36%) Query: 30 VTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKKFAENLKAG 89 + ++GGG +G A A G+ V ++D A + + AE + Sbjct: 38 LGMVGGGQLGRMFCFAAQAMGYRVAVLDPDPTSPAGAVADKHLRAAYDDEAALAELAQLC 97 Query: 90 DEFVEKTLSTIATSTDA 106 D + + A S D Sbjct: 98 DAVSTEFENVPAASLDF 114 >5AYV-A nrPDB Length = 309 Score = 28.9 bits (63), Expect = 3.0, Method: Composition-based stats. Identities = 17/72 (23%), Positives = 31/72 (43%), Gaps = 4/72 (5%) Query: 29 HVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKKFAENLKA 88 + V+G G +G+ + A G+ V L+ + E + A +K G L ++F KA Sbjct: 2 RIYVLGAGSIGSLFGALLARAGNDVTLIGRREQVDAINKNG----LHVFGAEEFTVKPKA 57 Query: 89 GDEFVEKTLSTI 100 E+ + Sbjct: 58 TIYAPEEPPDLL 69 >5U1O-A nrPDB Length = 458 Score = 28.9 bits (63), Expect = 3.1, Method: Composition-based stats. Identities = 16/54 (29%), Positives = 24/54 (44%) Query: 28 KHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKK 81 K V V+G G + IA V A G L + E L I ++L +V + + Sbjct: 175 KRVAVVGAGYIAVEIAGVLHALGTETHLFVRKESPLRSFDPMIIDTLVEVMEAE 228 >3FCA-A nrPDB Length = 291 Score = 28.9 bits (63), Expect = 3.1, Method: Composition-based stats. Identities = 11/33 (33%), Positives = 15/33 (45%) Query: 35 GGLMGAGIAQVAAATGHTVVLVDQTEDILAKSK 67 G MG IA + A GH V+L + + K Sbjct: 61 SGNMGIAIAMIGAKRGHRVILTMPETMSVERRK 93 >5Y8M-A nrPDB Length = 295 Score = 28.9 bits (63), Expect = 3.3, Method: Composition-based stats. Identities = 9/33 (27%), Positives = 15/33 (45%) Query: 26 IVKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQ 58 ++ + +G G MGA ++ GH V D Sbjct: 1 MMTTIAFLGLGNMGAPMSANLVGAGHVVRGFDP 33 >4GBJ-A nrPDB Length = 297 Score = 28.5 bits (62), Expect = 3.4, Method: Composition-based stats. Identities = 14/75 (18%), Positives = 32/75 (42%), Gaps = 4/75 (5%) Query: 28 KHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAK----SKKGIEESLRKVAKKKFA 83 + + +G G +G IA++ G+ +V+ ++T +E ++ + Sbjct: 6 EKIAFLGLGNLGTPIAEILLEAGYELVVWNRTASKAEPLTKLGATVVENAIDAITPGGIV 65 Query: 84 ENLKAGDEFVEKTLS 98 ++ A D VE+ S Sbjct: 66 FSVLADDAAVEELFS 80 >3X0V-A nrPDB Length = 541 Score = 28.5 bits (62), Expect = 3.5, Method: Composition-based stats. Identities = 8/38 (21%), Positives = 17/38 (44%) Query: 23 KKIIVKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTE 60 +++ + V ++G G+ G IA + + D E Sbjct: 3 EELPPRKVCIVGAGVSGLYIAMILDDLKIPNLTYDIFE 40 >1K4P-A nrPDB Length = 233 Score = 28.5 bits (62), Expect = 3.5, Method: Composition-based stats. Identities = 12/42 (28%), Positives = 17/42 (40%) Query: 170 HFFNPVPVMKLVEVIKTPMTSQKTFESLVDFSKALGKHPVSC 211 HF P V L V + E+ V+ + GK PV+ Sbjct: 130 HFRRPGHVFPLRAVAGGVRARRGHTEAGVELCRLAGKRPVAV 171 >4IQE-A nrPDB Length = 305 Score = 28.5 bits (62), Expect = 3.6, Method: Composition-based stats. Identities = 16/74 (21%), Positives = 27/74 (36%), Gaps = 8/74 (10%) Query: 186 TPMTSQKTFESLVDFSKALGKHPVSCKDTPGF--IVNRLLVPYLMEAIRLYERGDASKED 243 +TS + E D +A PV GF ++N A+ + E A+ + Sbjct: 70 GIVTSTEVAERARDLVRAT-DLPVLVDIDTGFGGVLN-----VARTAVEMVEAKVAAVQI 123 Query: 244 IDTAMKLGAGYPMG 257 D + G+ G Sbjct: 124 EDQQLPKKCGHLNG 137 >6EOI-A nrPDB Length = 298 Score = 28.5 bits (62), Expect = 3.8, Method: Composition-based stats. Identities = 10/33 (30%), Positives = 16/33 (48%) Query: 29 HVTVIGGGLMGAGIAQVAAATGHTVVLVDQTED 61 +T+ G G MG +A GHT + ++T Sbjct: 9 KLTIFGLGAMGTAMATQFLKQGHTPTVWNRTAA 41 >5FDN-A nrPDB Length = 987 Score = 28.5 bits (62), Expect = 3.9, Method: Composition-based stats. Identities = 12/72 (16%), Positives = 21/72 (29%), Gaps = 6/72 (8%) Query: 129 ELFKRLDKFAAEHTIFASNTSSLQITSIANATTRQDRFAGLHFFNPVPVMKLVEVIKTPM 188 ++ L I + TS + + Q H NP+ V+ L E + Sbjct: 535 KVISELPSDCFGAYIISMATS---PSDVLAVELLQREC---HVKNPLRVVPLFEKLADLE 588 Query: 189 TSQKTFESLVDF 200 + L Sbjct: 589 AAPAAVARLFSI 600 >3PII-A nrPDB Length = 339 Score = 28.5 bits (62), Expect = 3.9, Method: Composition-based stats. Identities = 14/39 (35%), Positives = 19/39 (48%) Query: 30 VTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKK 68 V + G G G Q A A G VV VD ++ L +K+ Sbjct: 168 VAIYGIGGFGHVAVQYAKAMGLNVVAVDIGDEKLELAKE 206 >1XDW-A nrPDB Length = 331 Score = 28.5 bits (62), Expect = 3.9, Method: Composition-based stats. Identities = 25/108 (23%), Positives = 39/108 (36%), Gaps = 17/108 (15%) Query: 29 HVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKKFAENLKA 88 V V+G G +G AQ+ G TV+ D E KGIE+ +V+ + E Sbjct: 148 TVGVVGLGRIGRVAAQIFHGMGATVIGEDVFE------IKGIEDYCTQVSLDEVLEKSDI 201 Query: 89 GDEFVE--KTLSTIATSTDAASVVHSTDLV---------VEAIVENLK 125 K + T + LV EA++E ++ Sbjct: 202 ITIHAPYIKENGAVVTRDFLKKMKDGAILVNCARGQLVDTEAVIEAVE 249 >4CPD-A nrPDB Length = 347 Score = 28.5 bits (62), Expect = 4.1, Method: Composition-based stats. Identities = 22/95 (23%), Positives = 32/95 (33%), Gaps = 24/95 (25%) Query: 29 HVTVIGG---GLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKKFAEN 85 V VIG GLM +AQV A+ + I E L + A Sbjct: 171 SVAVIGAGPVGLMAIEVAQVLGASKI-------------LAIDRIPERLERAASLGAIPI 217 Query: 86 LKAGDEFVEKTLSTIATSTDAASVVHSTDLVVEAI 120 E + + + T+ DLV+EA+ Sbjct: 218 NAEQ----ENPVRRVRSETN----DEGPDLVLEAV 244 >2EKL-A nrPDB Length = 313 Score = 28.2 bits (61), Expect = 4.5, Method: Composition-based stats. Identities = 9/31 (29%), Positives = 16/31 (51%) Query: 28 KHVTVIGGGLMGAGIAQVAAATGHTVVLVDQ 58 K + ++G G +G + +A A G V+ D Sbjct: 143 KTIGIVGFGRIGTKVGIIANAMGMKVLAYDI 173 >4Z6K-A nrPDB Length = 346 Score = 28.2 bits (61), Expect = 4.9, Method: Composition-based stats. Identities = 16/39 (41%), Positives = 20/39 (51%) Query: 30 VTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKK 68 V + G G +G Q A A G V VD +D LA +KK Sbjct: 168 VVISGIGGLGHMAVQYAIAMGLNVAAVDIDDDKLAFAKK 206 >4DGS-A nrPDB Length = 340 Score = 28.2 bits (61), Expect = 5.0, Method: Composition-based stats. Identities = 10/26 (38%), Positives = 15/26 (57%) Query: 28 KHVTVIGGGLMGAGIAQVAAATGHTV 53 K + V+G G +G +A A A G +V Sbjct: 172 KRIGVLGLGQIGRALASRAEAFGMSV 197 >3IK4-A nrPDB Length = 365 Score = 27.8 bits (60), Expect = 5.7, Method: Composition-based stats. Identities = 17/67 (25%), Positives = 26/67 (38%), Gaps = 4/67 (5%) Query: 40 AGIAQVAAATGHTVVLVDQTEDI---LAKSKKGIEESLR-KVAKKKFAENLKAGDEFVEK 95 AG+AQV A +G V + L +++G + K+ K AE LK Sbjct: 230 AGMAQVTAQSGFAVAADESARSAHDVLRIAREGTASVINIKLMKAGVAEGLKMIAIAQAA 289 Query: 96 TLSTIAT 102 L + Sbjct: 290 GLGLMIG 296 >1QYC-A nrPDB Length = 308 Score = 27.8 bits (60), Expect = 5.9, Method: Composition-based stats. Identities = 17/94 (18%), Positives = 34/94 (36%), Gaps = 14/94 (14%) Query: 28 KHVTVIGG-GLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKKFAENL 86 + +IG G +G +A+ + GH L+ + + S K + E+ Sbjct: 5 SRILLIGATGYIGRHVAKASLDLGHPTFLLVRESTASSNS-----------EKAQLLESF 53 Query: 87 KAGDEFVEKTLSTIATSTDAASVVHSTDLVVEAI 120 KA + +I V + D+V+ + Sbjct: 54 KASGANI--VHGSIDDHASLVEAVKNVDVVISTV 85 >3VPX-A nrPDB Length = 364 Score = 27.8 bits (60), Expect = 6.3, Method: Composition-based stats. Identities = 8/43 (18%), Positives = 18/43 (41%) Query: 28 KHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGI 70 K V V G G + + + G +++ D E+ + ++ Sbjct: 174 KTVAVQGVGNVAYALCEYLHEEGAKLIITDINEEAVQRAVDAF 216 >4EEZ-A nrPDB Length = 348 Score = 27.8 bits (60), Expect = 6.7, Method: Composition-based stats. Identities = 21/98 (21%), Positives = 36/98 (36%), Gaps = 9/98 (9%) Query: 32 VIGGGLMGAGIAQVAAAT--GHTVVLVDQTEDILAKSKKGIEE------SLRKVAKKKFA 83 + G G +G +A A G V+ VD +D L +KK + + V + K Sbjct: 169 IFGAGGLGN-LAIQYAKNVFGAKVIAVDINQDKLNLAKKIGADVTINSGDVNPVDEIKKI 227 Query: 84 ENLKAGDEFVEKTLSTIATSTDAASVVHSTDLVVEAIV 121 + ++ IA AS+ +V A+ Sbjct: 228 TGGLGVQSAIVCAVARIAFEQAVASLKPMGKMVAVAVP 265 >4E4T-A nrPDB Length = 419 Score = 27.8 bits (60), Expect = 6.8, Method: Composition-based stats. Identities = 14/77 (18%), Positives = 27/77 (35%) Query: 30 VTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKKFAENLKAG 89 + ++GGG +G A + G+ V ++D A + + AE Sbjct: 38 LGMVGGGQLGRMFCFAAQSMGYRVAVLDPDPASPAGAVADRHLRAAYDDEAALAELAGLC 97 Query: 90 DEFVEKTLSTIATSTDA 106 + + + A S D Sbjct: 98 EAVSTEFENVPAASLDF 114 >4AVY-A nrPDB Length = 242 Score = 27.8 bits (60), Expect = 7.1, Method: Composition-based stats. Identities = 20/113 (17%), Positives = 40/113 (35%), Gaps = 7/113 (6%) Query: 28 KHVTVIGGGL-MGAGIAQVAAATGHTVVLVDQTEDILAKS------KKGIEESLRKVAKK 80 + V V GG +GA IA A G VV + D + ++ ++ + + ++ Sbjct: 12 QQVLVTGGSSGIGAAIAMQFAELGAEVVALGLDADGVHAPRHPRIRREELDITDSQRLQR 71 Query: 81 KFAENLKAGDEFVEKTLSTIATSTDAASVVHSTDLVVEAIVENLKVKNELFKR 133 F + +S D A+ L + A + ++ L + Sbjct: 72 LFEALPRLDVLVNNAGISRDREEYDLATFERVLRLNLSAAMLASQLARPLLAQ 124 >4DIO-A nrPDB Length = 405 Score = 27.4 bits (59), Expect = 7.5, Method: Composition-based stats. Identities = 14/97 (14%), Positives = 29/97 (29%) Query: 21 SAKKIIVKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKK 80 +A + + V+G G+ G A G V D + + + ++ Sbjct: 184 AAGTVPAAKIFVMGAGVAGLQAIATARRLGAVVSATDVRPAAKEQVASLGAKFIAVEDEE 243 Query: 81 KFAENLKAGDEFVEKTLSTIATSTDAASVVHSTDLVV 117 A G + + A + D+V+ Sbjct: 244 FKAAETAGGYAKEMSGEYQVKQAALVAEHIAKQDIVI 280 >2IZ1-A nrPDB Length = 474 Score = 27.4 bits (59), Expect = 7.5, Method: Composition-based stats. Identities = 9/32 (28%), Positives = 18/32 (56%) Query: 29 HVTVIGGGLMGAGIAQVAAATGHTVVLVDQTE 60 + V+G +MG +A + G+TV + ++T Sbjct: 7 NFGVVGMAVMGKNLALNVESRGYTVAIYNRTT 38 >3RWB-A nrPDB Length = 247 Score = 27.4 bits (59), Expect = 8.4, Method: Composition-based stats. Identities = 40/230 (17%), Positives = 72/230 (31%), Gaps = 21/230 (9%) Query: 28 KHVTVIGGGL-MGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKKFAENL 86 K V G +G IA AA G TV++ D + + I + R +A Sbjct: 7 KTALVTGAAQGIGKAIAARLAADGATVIVSDINAEGAKAAAASIGKKARAIAADISDPGS 66 Query: 87 KAGDEFVEKTLSTIATSTDAASVVHSTDLVVEAIVENLKVKNELFKRLDKFAAEHTIFAS 146 + L + +V++ +V +++ + + ++++ T + Sbjct: 67 VKALFAEIQAL-----TGGIDILVNNASIVPFVAWDDVDLDH--WRKIIDVNLTGTFIVT 119 Query: 147 NTSSLQITSIANATTRQDRFAGLHFFNPVPVMKLVEVIKTPMTSQKTFESLVDFSKALGK 206 + A R A FF P M K + LGK Sbjct: 120 RAGT-DQMRAAGKAGRVISIASNTFFAGTPNMAAYVAAKG-----GVIGFTRALATELGK 173 Query: 207 HPVSCKD-TPGFIVNR-LLVPYLMEAIRLYE-----RGDASKEDIDTAMK 249 + ++ TPG I + + EA E +G E I + Sbjct: 174 YNITANAVTPGLIESDGVKASPHNEAFGFVEMLQAMKGKGQPEHIADVVS 223 >1JAY-A nrPDB Length = 212 Score = 27.4 bits (59), Expect = 8.6, Method: Composition-based stats. Identities = 11/28 (39%), Positives = 17/28 (60%), Gaps = 1/28 (3%) Query: 29 HVTVIGG-GLMGAGIAQVAAATGHTVVL 55 V ++GG G +G G+A A GH +V+ Sbjct: 2 RVALLGGTGNLGKGLALRLATLGHEIVV 29 >3A28-C nrPDB Length = 258 Score = 27.4 bits (59), Expect = 8.7, Method: Composition-based stats. Identities = 10/42 (23%), Positives = 20/42 (47%), Gaps = 2/42 (4%) Query: 27 VKHVTVIGGGL--MGAGIAQVAAATGHTVVLVDQTEDILAKS 66 + V ++ GG +G GI++ AA G + + D + + Sbjct: 1 MSKVAMVTGGAQGIGRGISEKLAADGFDIAVADLPQQEEQAA 42 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.308 0.130 0.330 Lambda K H 0.267 0.0399 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 10,146,204 Number of Sequences: 36641 Number of extensions: 366775 Number of successful extensions: 2160 Number of sequences better than 10.0: 271 Number of HSP's better than 10.0 without gapping: 246 Number of HSP's successfully gapped in prelim test: 109 Number of HSP's that attempted gapping in prelim test: 1769 Number of HSP's gapped (non-prelim): 386 length of query: 314 length of database: 10,336,785 effective HSP length: 97 effective length of query: 217 effective length of database: 6,782,608 effective search space: 1471825936 effective search space used: 1471825936 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 59 (27.4 bits)