BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q16831 (310 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 3EUF-A nrPDB 641 0.0 3KUK-A nrPDB 520 e-148 3P0E-A nrPDB 398 e-111 4TXN-A nrPDB 249 1e-66 5CYF-A nrPDB 233 1e-61 1U1E-A nrPDB 59 2e-09 4R31-A nrPDB 59 4e-09 4I2V-A nrPDB 57 9e-09 3PNS-A nrPDB 57 1e-08 4R2W-A nrPDB 51 5e-07 3TL6-A nrPDB 45 4e-05 1ODL-A nrPDB 44 1e-04 3BJE-A nrPDB 43 1e-04 4M3N-A nrPDB 41 6e-04 2ISC-A nrPDB 41 7e-04 3QPB-A nrPDB 38 0.006 3MB8-A nrPDB 35 0.046 1VHW-A nrPDB 33 0.13 4TYM-A nrPDB 33 0.16 1PR2-A nrPDB 33 0.22 4LDN-A nrPDB 33 0.22 4LKR-A nrPDB 32 0.24 3OCC-A nrPDB 32 0.31 4M7W-A nrPDB 32 0.38 3UAY-A nrPDB 32 0.41 4LNH-A nrPDB 32 0.43 1JE0-A nrPDB 31 0.80 4DAO-A nrPDB 30 1.1 6F5I-A nrPDB 30 1.2 6DZ3-A nrPDB 30 1.2 1P88-A nrPDB 30 1.4 6A9U-A nrPDB 30 1.4 3FJZ-A nrPDB 29 2.6 1NRK-A nrPDB 29 2.6 5VM8-A nrPDB 29 3.0 1NXZ-A nrPDB 27 8.5 >3EUF-A nrPDB Length = 328 Score = 641 bits (1653), Expect = 0.0, Method: Compositional matrix adjust. Identities = 310/310 (100%), Positives = 310/310 (100%) Query: 1 MAATGANAEKAESHNDCPVRLLNPNIAKMKEDILYHFNLTTSRHNFPALFGDVKFVCVGG 60 MAATGANAEKAESHNDCPVRLLNPNIAKMKEDILYHFNLTTSRHNFPALFGDVKFVCVGG Sbjct: 19 MAATGANAEKAESHNDCPVRLLNPNIAKMKEDILYHFNLTTSRHNFPALFGDVKFVCVGG 78 Query: 61 SPSRMKAFIRCVGAELGLDCPGRDYPNICAGTDRYAMYKVGPVLSVSHGMGIPSISIMLH 120 SPSRMKAFIRCVGAELGLDCPGRDYPNICAGTDRYAMYKVGPVLSVSHGMGIPSISIMLH Sbjct: 79 SPSRMKAFIRCVGAELGLDCPGRDYPNICAGTDRYAMYKVGPVLSVSHGMGIPSISIMLH 138 Query: 121 ELIKLLYYARCSNVTIIRIGTSGGIGLEPGTVVITEQAVDTCFKAEFEQIVLGKRVIRKT 180 ELIKLLYYARCSNVTIIRIGTSGGIGLEPGTVVITEQAVDTCFKAEFEQIVLGKRVIRKT Sbjct: 139 ELIKLLYYARCSNVTIIRIGTSGGIGLEPGTVVITEQAVDTCFKAEFEQIVLGKRVIRKT 198 Query: 181 DLNKKLVQELLLCSAELSEFTTVVGNTMCTLDFYEGQGRLDGALCSYTEKDKQAYLEAAY 240 DLNKKLVQELLLCSAELSEFTTVVGNTMCTLDFYEGQGRLDGALCSYTEKDKQAYLEAAY Sbjct: 199 DLNKKLVQELLLCSAELSEFTTVVGNTMCTLDFYEGQGRLDGALCSYTEKDKQAYLEAAY 258 Query: 241 AAGVRNIEMESSVFAAMCSACGLQAAVVCVTLLNRLEGDQISSPRNVLSEYQQRPQRLVS 300 AAGVRNIEMESSVFAAMCSACGLQAAVVCVTLLNRLEGDQISSPRNVLSEYQQRPQRLVS Sbjct: 259 AAGVRNIEMESSVFAAMCSACGLQAAVVCVTLLNRLEGDQISSPRNVLSEYQQRPQRLVS 318 Query: 301 YFIKKKLSKA 310 YFIKKKLSKA Sbjct: 319 YFIKKKLSKA 328 >3KUK-A nrPDB Length = 309 Score = 520 bits (1338), Expect = e-148, Method: Compositional matrix adjust. Identities = 249/310 (80%), Positives = 275/310 (88%), Gaps = 1/310 (0%) Query: 1 MAATGANAEKAESHNDCPVRLLNPNIAKMKEDILYHFNLTTSRHNFPALFGDVKFVCVGG 60 MA+T A EK E HND V+L NP+IA MKEDILYHF+L+TS H+FPA+FGDVKFVCVGG Sbjct: 1 MASTAAETEKPEDHNDL-VQLCNPHIAAMKEDILYHFSLSTSTHDFPAMFGDVKFVCVGG 59 Query: 61 SPSRMKAFIRCVGAELGLDCPGRDYPNICAGTDRYAMYKVGPVLSVSHGMGIPSISIMLH 120 SPSRMKAFI+ V ELG PG DYPNIC GTDRYAM+KVGPVLSVSHGMG+PSI+IMLH Sbjct: 60 SPSRMKAFIKYVAMELGFAHPGADYPNICEGTDRYAMFKVGPVLSVSHGMGVPSIAIMLH 119 Query: 121 ELIKLLYYARCSNVTIIRIGTSGGIGLEPGTVVITEQAVDTCFKAEFEQIVLGKRVIRKT 180 ELIKLLY+A CS VT+IRIGTSGGIGLEPG+VVIT QAVD CFK EFEQIVLGKR +R T Sbjct: 120 ELIKLLYHAHCSGVTLIRIGTSGGIGLEPGSVVITRQAVDPCFKPEFEQIVLGKREVRNT 179 Query: 181 DLNKKLVQELLLCSAELSEFTTVVGNTMCTLDFYEGQGRLDGALCSYTEKDKQAYLEAAY 240 DL+++LVQEL CSAEL EF TVVGNTMCTLDFYEGQGRLDGALCSYTEKDKQ YL AAY Sbjct: 180 DLDEQLVQELARCSAELGEFPTVVGNTMCTLDFYEGQGRLDGALCSYTEKDKQDYLRAAY 239 Query: 241 AAGVRNIEMESSVFAAMCSACGLQAAVVCVTLLNRLEGDQISSPRNVLSEYQQRPQRLVS 300 AAG+RNIEME+SVFAAMC+ACGL+AAVVCVTLLNRLEGDQISSP +VL+EYQQRPQRLV Sbjct: 240 AAGIRNIEMEASVFAAMCNACGLRAAVVCVTLLNRLEGDQISSPHDVLAEYQQRPQRLVG 299 Query: 301 YFIKKKLSKA 310 FIKK+L +A Sbjct: 300 QFIKKRLMQA 309 >3P0E-A nrPDB Length = 297 Score = 398 bits (1023), Expect = e-111, Method: Compositional matrix adjust. Identities = 191/289 (66%), Positives = 231/289 (79%) Query: 19 VRLLNPNIAKMKEDILYHFNLTTSRHNFPALFGDVKFVCVGGSPSRMKAFIRCVGAELGL 78 V + NP + M EDILYH +L T HN PA+FGDVKFVCVGGSP+RMKAF + ELG Sbjct: 8 VHVKNPYLDLMDEDILYHLDLGTKTHNLPAMFGDVKFVCVGGSPNRMKAFALFMHKELGF 67 Query: 79 DCPGRDYPNICAGTDRYAMYKVGPVLSVSHGMGIPSISIMLHELIKLLYYARCSNVTIIR 138 + D +ICAGTDRY MYK GPVL++SHGMGIPSISIMLHELIKLL++ARC +VTIIR Sbjct: 68 EEAEEDIKDICAGTDRYCMYKTGPVLAISHGMGIPSISIMLHELIKLLHHARCCDVTIIR 127 Query: 139 IGTSGGIGLEPGTVVITEQAVDTCFKAEFEQIVLGKRVIRKTDLNKKLVQELLLCSAELS 198 IGTSGGIG+ PGTVVIT+ AVD+ FK FEQ++L V R T+L+K+L +EL CS E+ Sbjct: 128 IGTSGGIGIAPGTVVITDIAVDSFFKPRFEQVILDNIVTRSTELDKELSEELFNCSKEIP 187 Query: 199 EFTTVVGNTMCTLDFYEGQGRLDGALCSYTEKDKQAYLEAAYAAGVRNIEMESSVFAAMC 258 F T+VG+TMCT DFYEGQGRLDGALCS++ + K YL+ A+ AGVRNIEMES+VFAAMC Sbjct: 188 NFPTLVGHTMCTYDFYEGQGRLDGALCSFSREKKLDYLKRAFKAGVRNIEMESTVFAAMC 247 Query: 259 SACGLQAAVVCVTLLNRLEGDQISSPRNVLSEYQQRPQRLVSYFIKKKL 307 CGL+AAVVCVTLL+RL+ DQI+ P +VL EYQQRPQ L+S FI+++L Sbjct: 248 GLCGLKAAVVCVTLLDRLDCDQINLPHDVLVEYQQRPQLLISNFIRRRL 296 >4TXN-A nrPDB Length = 296 Score = 249 bits (635), Expect = 1e-66, Method: Compositional matrix adjust. Identities = 125/287 (43%), Positives = 186/287 (64%), Gaps = 4/287 (1%) Query: 21 LLNPNIAKMKEDILYHFNLTTSRHNFPALFGDVKFVCVGGSPSRMKAFIRCVGAELGLDC 80 ++N +++++ ED+ +HF TT +F FGDVKFVCV GS R+ F + GL Sbjct: 7 IVNSHLSELDEDVFHHFGFTTKSFDFKEKFGDVKFVCVCGSSGRIHNFAISMAKLAGLAL 66 Query: 81 PGRDYPNICAGTDRYAMYKVGPVLSVSHGMGIPSISIMLHELIKLLYYARCSNVTIIRIG 140 P NI R+ +YKV +L HGMGIPS IMLHE+ KLL+YA C +V IR+G Sbjct: 67 P---VENIAGSHARFVLYKVDHILFADHGMGIPSALIMLHEVTKLLHYAGCKDVLFIRLG 123 Query: 141 TSGGIGLEPGTVVITEQAVDTCFKAEFEQIVLGKRVIRKTDLNKKLVQELLLCSAELS-E 199 TSGG+G++PGT+V++++ V+T + E +LGK V R+T ++ V EL S LS E Sbjct: 124 TSGGLGVKPGTIVLSDRCVNTKLEPYNELCILGKPVRRQTIVDLNTVNELKKLSENLSLE 183 Query: 200 FTTVVGNTMCTLDFYEGQGRLDGALCSYTEKDKQAYLEAAYAAGVRNIEMESSVFAAMCS 259 + VVG T+ DFYE QGRLDG++C++++++K A+L++AY G+RN+EME + + C Sbjct: 184 CSVVVGGTIAANDFYEEQGRLDGSICTFSKEEKLAFLQSAYEHGIRNMEMEGTAITSHCY 243 Query: 260 ACGLQAAVVCVTLLNRLEGDQISSPRNVLSEYQQRPQRLVSYFIKKK 306 G +A +VCVT +NRLEGDQI+ + + + QRP +LV ++K+ Sbjct: 244 LTGHRAILVCVTAVNRLEGDQITISTDEFTLFAQRPGQLVGEYLKRN 290 >5CYF-A nrPDB Length = 296 Score = 233 bits (593), Expect = 1e-61, Method: Compositional matrix adjust. Identities = 114/286 (39%), Positives = 184/286 (64%), Gaps = 4/286 (1%) Query: 21 LLNPNIAKMKEDILYHFNLTTSRHNFPALFGDVKFVCVGGSPSRMKAFIRCVGAELGLDC 80 ++N +++++ ED+ +HF TT +F FGDVKFVCV GS R+ F + GL Sbjct: 7 IVNSHLSELDEDVFHHFGFTTKSFDFKEKFGDVKFVCVCGSSGRIHNFAISMAKLAGLAL 66 Query: 81 PGRDYPNICAGTDRYAMYKVGPVLSVSHGMGIPSISIMLHELIKLLYYARCSNVTIIRIG 140 P NI R+ +YKV +L HG+GIPS I++HE+ KLLYYA C +V IR+G Sbjct: 67 P---VENIAGSHARFVLYKVDHILFADHGIGIPSTLILMHEVTKLLYYAGCKDVLFIRLG 123 Query: 141 TSGGIGLEPGTVVITEQAVDTCFKAEFEQIVLGKRVIRKTDLNKKLVQELLLCSAELS-E 199 TS G+G++PGT+V++++ V+T + E +LGK V R+T ++ V EL S LS + Sbjct: 124 TSDGLGVKPGTIVLSDRCVNTKLEPYNELCILGKPVRRQTKVDSNAVNELKKLSENLSLK 183 Query: 200 FTTVVGNTMCTLDFYEGQGRLDGALCSYTEKDKQAYLEAAYAAGVRNIEMESSVFAAMCS 259 + VVG T+ DFYE GRL+G++C++++++K A+L++ Y G+RN+EME + + C+ Sbjct: 184 CSVVVGGTITANDFYEELGRLNGSICTFSKEEKLAFLQSVYDHGIRNMEMEGAAITSHCN 243 Query: 260 ACGLQAAVVCVTLLNRLEGDQISSPRNVLSEYQQRPQRLVSYFIKK 305 G +A +VCVT++NRLE D++++ + ++Q P +LV ++K+ Sbjct: 244 LTGHRAILVCVTVVNRLETDEVTTSTDEFKLFEQLPGQLVGEYLKR 289 >1U1E-A nrPDB Length = 256 Score = 59.3 bits (142), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 56/178 (31%), Positives = 83/178 (46%), Gaps = 15/178 (8%) Query: 102 PVLSVSHGMGIPSISIMLHELIKLLYYARCSNVTIIRIGTSGGI--GLEPGTVVITEQAV 159 PV+ S G+G PS SI + EL +L T +RIGT+G I + G V++T +V Sbjct: 64 PVIVCSTGIGGPSTSIAVEELAQLGIR------TFLRIGTTGAIQPHINVGDVLVTTASV 117 Query: 160 DTCFKAEFEQIVLGKRVIRKTDLNKKLVQELLLCSAELSEFTTVVGNTMCTLDFYEGQGR 219 A L + + LV+ +A+ TT VG T + FY GQ R Sbjct: 118 R-LDGASLHFAPLEFPAVADFECTTALVE-----AAKSIGATTHVGVTASSDTFYPGQER 171 Query: 220 LDGALCSYTEKDKQAYLEAAYAAGVRNIEMESSVFAAMCSACGLQAAVVCVTLLNRLE 277 D + + +E A GV N EMES+ MC++ GL+A +V ++NR + Sbjct: 172 YD-TYSGRVVRHFKGSMEEWQAMGVMNYEMESATLLTMCASQGLRAGMVAGVIVNRTQ 228 >4R31-A nrPDB Length = 279 Score = 58.5 bits (140), Expect = 4e-09, Method: Compositional matrix adjust. Identities = 69/258 (26%), Positives = 105/258 (40%), Gaps = 52/258 (20%) Query: 34 LYHFNLTTSRHNFPALFGDVKFVCVGGSPSRMKAFIRCVGAELGLDCPGRDYPNICAGTD 93 ++H LT A+ K + G P+R + + + D P A + Sbjct: 26 VFHLGLTK------AMLKGAKIAVIPGDPARSERIAQRM-----------DKPEFLASSR 68 Query: 94 RYAMY----KVGPVLSVSHGMGIPSISIMLHELIKLLYYARCSNVTIIRIGTSGGIG--L 147 + + + PV+ S G+G PS+SI + EL A+ T +RIGT+G I + Sbjct: 69 EFTSWLGYLENEPVVVCSTGIGGPSVSICVEEL------AQLGVGTFLRIGTTGAIQPYI 122 Query: 148 EPGTVVITEQAVDTCFKAEFEQIVLGKRVIRKTDLNKKLVQEL-----LLCSAELSEFTT 202 G V++T AV L L V + L +A T Sbjct: 123 NVGDVLVTTGAVR-----------LDGASRHFAPLEYPAVADFSCTNALYSAAVAQGITP 171 Query: 203 VVGNTMCTLDFYEGQGRLDGALCSYTEKDKQAY---LEAAYAAGVRNIEMESSVFAAMCS 259 VG T + FY GQ R D +++ K AY L+ V N EMES+ MC+ Sbjct: 172 YVGITASSDTFYPGQERYD----TFSGKVYPAYQGSLKQWQDLNVMNYEMESATLFTMCA 227 Query: 260 ACGLQAAVVCVTLLNRLE 277 A GL+A +V ++NR + Sbjct: 228 ALGLKAGMVAGVIVNRTQ 245 >4I2V-A nrPDB Length = 253 Score = 57.0 bits (136), Expect = 9e-09, Method: Compositional matrix adjust. Identities = 66/256 (25%), Positives = 107/256 (41%), Gaps = 38/256 (14%) Query: 29 MKEDILYHFNLTTSRHNFPALFGDVKFVCVGGSPSRMKAFIRCVGAELGLDCPGRDYPNI 88 M + ++H LT + V G P R++ + + + L R++ + Sbjct: 1 MAKSDVFHLGLTKND------LQGATLAIVPGDPQRVEKIAKLMDNPVHL-ASHREFTSW 53 Query: 89 CAGTDRYAMYKVGPVLSVSHGMGIPSISIMLHELIKLLYYARCSNVTIIRIGTSGGI--G 146 A D A V+ S G+G PS SI + EL +L T +RIGT+G I Sbjct: 54 RAELDGKA------VIVCSTGIGGPSTSIAVEELAQLGVR------TFLRIGTTGAIQPH 101 Query: 147 LEPGTVVITEQAVDTCFKAEFEQIVLGKRVIRKTDLNKKLVQEL-----LLCSAELSEFT 201 + G V++T AV L + + V + L+ +A+ T Sbjct: 102 INVGDVLVTTAAVR-----------LDGASLHFAPMEFPAVADFSCTTALVNAAKSVGAT 150 Query: 202 TVVGNTMCTLDFYEGQGRLDGALCSYTEKDKQAYLEAAYAAGVRNIEMESSVFAAMCSAC 261 T +G T + FY GQ R D + + +E + GV N EMES+ MC++ Sbjct: 151 THIGITASSDTFYPGQERYD-TFSGRVVRHFKGSMEEWQSMGVMNYEMESATLLTMCASQ 209 Query: 262 GLQAAVVCVTLLNRLE 277 GL+A +V ++NR + Sbjct: 210 GLRAGMVAGVIVNRTQ 225 >3PNS-A nrPDB Length = 261 Score = 56.6 bits (135), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 70/280 (25%), Positives = 115/280 (41%), Gaps = 38/280 (13%) Query: 34 LYHFNLTTSRHNFPALFGDVKFVCVGGSPSRMKAFIRCVGAELGLDCPGRDYPNICAGTD 93 ++H +T + N L + G P+R++ AEL D P A Sbjct: 13 VFHLGVTEADLNGATL------AIIPGDPARVQKI-----AEL------MDNPVFLASHR 55 Query: 94 RYAMYKV----GPVLSVSHGMGIPSISIMLHELIKLLYYARCSNVTIIRIGTSGGIG--L 147 Y +Y+ V+ S G+G PS SI + EL +L T +R+GT+G I + Sbjct: 56 EYTVYRAELDGQSVVVCSTGIGGPSTSIAVEELAQLGVR------TFLRVGTTGAIQPHV 109 Query: 148 EPGTVVITEQAVDTCFKAEFEQIVLGKRVIRKTDLNKKLVQELLLCSAELSEFTTVVGNT 207 G +++T +V + L + + V + +A+ S T +G T Sbjct: 110 NVGDMIVTTGSV------RLDGASLHFAPMEFPAVPDFDVATAMKAAAQESGATVHMGVT 163 Query: 208 MCTLDFYEGQGRLDGALCSYTEKDKQAYLEAAYAAGVRNIEMESSVFAAMCSACGLQAAV 267 + FY GQ R D + Q ++ GV N EMES+ MC++ GL+A Sbjct: 164 ASSDTFYPGQERYD-TFTGRVVRRFQGSMKEWQDMGVLNFEMESATLLTMCASSGLKAGC 222 Query: 268 VCVTLLNRLEGDQISSPRNVLSEYQQRPQRLVSYFIKKKL 307 V ++NR + + L E + R ++V +K L Sbjct: 223 VAGVIINRTQKE--IPDHATLKETEARSIKVVVEAARKML 260 >4R2W-A nrPDB Length = 252 Score = 51.2 bits (121), Expect = 5e-07, Method: Compositional matrix adjust. Identities = 66/246 (26%), Positives = 99/246 (40%), Gaps = 28/246 (11%) Query: 34 LYHFNLTTSRHNFPALFGDVKFVCVGGSPSRMKAFIRCVGAELGLDCPGRDYPNICAGTD 93 ++H LT A+ V G P R+K + L R+Y + A Sbjct: 4 VFHLGLTK------AMLDGATLAIVPGDPERVKRIAELMDNATFL-ASHREYTSYLA--- 53 Query: 94 RYAMYKVGPVLSVSHGMGIPSISIMLHELIKLLYYARCSNVTIIRIGTSGGI--GLEPGT 151 YA K PV+ S G+G PS SI + EL +L T +R+GT+G I + G Sbjct: 54 -YADGK--PVVICSTGIGGPSTSIAVEELAQLGVN------TFLRVGTTGAIQPHVNVGD 104 Query: 152 VVITEQAVDTCFKAEFEQIVLGKRVIRKTDLNKKLVQELLLCSAELSEFTTVVGNTMCTL 211 V++T+ +V A + + + +V E +G T + Sbjct: 105 VIVTQASVR-LDGASLHFAPMEFPAVANFECTTAMVAACRDAGVEPH-----IGVTASSD 158 Query: 212 DFYEGQGRLDGALCSYTEKDKQAYLEAAYAAGVRNIEMESSVFAAMCSACGLQAAVVCVT 271 FY GQ R D T + + E GV N EMES+ MC+ G +AA V Sbjct: 159 TFYPGQERYDTVTGRVTRRFAGSMKEW-QDMGVLNYEMESATLFTMCATQGWRAACVAGV 217 Query: 272 LLNRLE 277 ++NR + Sbjct: 218 IVNRTQ 223 >3TL6-A nrPDB Length = 242 Score = 45.1 bits (105), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 44/139 (31%), Positives = 61/139 (43%), Gaps = 27/139 (19%) Query: 87 NICAGTDRYAMYKVGPVLSV-SHGMGIPSISIMLHELIKLLYYARCSNVTIIRIGTSGGI 145 N G Y Y G LSV +HGMG+PSI I +EL R IIRIG++G Sbjct: 49 NSVRGAVGYTGYYKGVKLSVQAHGMGMPSIGIYAYELFNFYGVKR-----IIRIGSAGAF 103 Query: 146 --GLEPGTVVITEQAVDTCFKAEFEQIVLGKRVIRKTDLNKKL--VQELLLC-----SAE 196 L+ G +VI + C+ + FE R+ D+ K + + LC +AE Sbjct: 104 DESLKLGDIVI---GMGACYDSNFE---------RQYDIPGKYSCIADFQLCREAVDAAE 151 Query: 197 LSEFTTVVGNTMCTLDFYE 215 + VGN FY+ Sbjct: 152 KLGYRYKVGNIYSANYFYD 170 >1ODL-A nrPDB Length = 235 Score = 43.5 bits (101), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 67/250 (26%), Positives = 106/250 (42%), Gaps = 43/250 (17%) Query: 51 GDV-KFVCVGGSPSRMKAFIRCVGAELGLDCPGR--DYPNICAGTDRYAMYKVGPVLSVS 107 GDV + V + G P R + + L P R D+ + T +YK PV + Sbjct: 11 GDVAERVLLPGDPGRAEWIAKTF-----LQNPRRYNDHRGLWGYT---GLYKGVPVSVQT 62 Query: 108 HGMGIPSISIMLHELIKLLYYARCSNVTIIRIGTSGGIG--LEPGTVVITEQAVDTCFKA 165 GMG PS +I++ EL++L ++R+GT+G L PG +++ + AV Sbjct: 63 TGMGTPSAAIVVEELVRL------GARVLVRVGTAGAASSDLAPGELIVAQGAV--PLDG 114 Query: 166 EFEQIVLGKRVIRKTDLNKKLVQELLLCSAELSEFTTVVGNTMCTLDFYEGQGRLDGALC 225 Q + G+ D V L AE + VG FY Sbjct: 115 TTRQYLEGRPYAPVPDPE---VFRALWRRAEALGYPHRVGLVASEDAFY----------- 160 Query: 226 SYTEKDKQAYLEAAYAAGVRNIEMESSVFAAMCSACGLQ-AAVVCVTLLNRLEGDQISSP 284 + T ++ +A+ A Y GV EME+S + G++ A++ V+ NR+ GD +P Sbjct: 161 ATTPEEARAW--ARY--GVLAFEMEASALFLLGRMRGVRTGAILAVS--NRI-GDPELAP 213 Query: 285 RNVLSEYQQR 294 VL E +R Sbjct: 214 PEVLQEGVRR 223 >3BJE-A nrPDB Length = 349 Score = 43.1 bits (100), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 64/266 (24%), Positives = 100/266 (37%), Gaps = 68/266 (25%) Query: 83 RDYPNICAGTDRYAMYKVGPVLSVSHGMGIPSISIMLHELIKLLYYA------------- 129 RD+ I T YK PV +S GMG+ +I I+L+E+ L Y Sbjct: 71 RDHREIRFAT---GTYKGTPVTVISTGMGVDNIEIVLNEIHALKEYDMERGQWRHRKGDA 127 Query: 130 ---------RCSNVTIIRIGTSGGIG--LEPGTVVITEQAV---DTCF------------ 163 S + IIR+GT G + P + +T A+ +T Sbjct: 128 DAPSAGPFFDPSTMKIIRLGTCGSPAESVPPLALAVTRHAIGMDNTSLYYSAGTRETSKD 187 Query: 164 KAEFEQIVLGKRVIRKTDLNKKLVQELL---LCSA----------ELSEFTTVVGNTMCT 210 + E +IV + +R D+ + + +C+A E + V+G T Sbjct: 188 QQEIRRIVREQTGLRAIDIYTSMAHPNITKSICAACDAHNAATGSEADKQQYVIGTTATA 247 Query: 211 LDFYEGQGRLDGALCSY----TEKDKQAYLEAAYAAGVR---NIEMESSVFAAMCSACGL 263 FY QGR G + ++ L+ + GV NIEME+S + G Sbjct: 248 SGFYGCQGRRVGRFMKHLTVPNMVEELGSLKFNLSNGVEVVTNIEMETSAICYLSDMLGY 307 Query: 264 QAAVVCVTLLNRLE------GDQISS 283 QA CV + R+ GDQ+ + Sbjct: 308 QAGAACVVVSKRVGEKKMFLGDQLDA 333 >4M3N-A nrPDB Length = 254 Score = 41.2 bits (95), Expect = 6e-04, Method: Compositional matrix adjust. Identities = 49/191 (25%), Positives = 84/191 (43%), Gaps = 36/191 (18%) Query: 109 GMGIPSISIMLHELIKLLYYARCSNVTIIRIGTSGGIG--LEPGTVVITEQAVDTCFKAE 166 GMGIPS SI +HEL++ +Y C T+IR+GT+G I L+ +VI + A C + Sbjct: 85 GMGIPSASIYIHELVQ--FYG-CK--TLIRVGTAGAITERLKLRDLVIAQAA---CTDSS 136 Query: 167 FEQIVLGKR---VIRKTDLNKKLVQELLLCSAELSEFTTVVGNTMCTLDFYEGQGRLDGA 223 + + I DL ++ ++ A+ VGN + T FY Q Sbjct: 137 INNLRFAGQNYAPIATFDLLRRAYEQ-----AQSRGMPVHVGNVLSTDTFYHDQPNPYQL 191 Query: 224 LCSYTEKDKQAYLEAAYAAGVRNIEMESSVFAAMCSACGLQAAVVCV-TLLNRLEGDQIS 282 + GV +EME++ + + G+QA +C+ T+ + L + + Sbjct: 192 WAQF---------------GVLAVEMEAAGLYTLAAKFGVQA--LCILTISDHLITGEKT 234 Query: 283 SPRNVLSEYQQ 293 +P+ + Q Sbjct: 235 TPQERQETFDQ 245 >2ISC-A nrPDB Length = 239 Score = 40.8 bits (94), Expect = 7e-04, Method: Compositional matrix adjust. Identities = 36/103 (34%), Positives = 46/103 (44%), Gaps = 15/103 (14%) Query: 50 FGDVKFVCVGGSPSRMKAFIRCVGAELGLDCPGRDYPNICAGTDRY-AMYKVGPVLSVSH 108 F + +C G P R K AE L+ P N G Y YK P+ + H Sbjct: 12 FAETVLMC--GDPLRAKLI-----AETYLENP--KLVNNVRGIQGYTGTYKGKPISVMGH 62 Query: 109 GMGIPSISIMLHELIKLLYYARCSNVTIIRIGTSGGIGLEPGT 151 GMG+PSI I EL Y+ TIIR+GT G I ++ T Sbjct: 63 GMGLPSICIYAEEL-----YSTYKVKTIIRVGTCGAIDMDIHT 100 >3QPB-A nrPDB Length = 282 Score = 37.7 bits (86), Expect = 0.006, Method: Compositional matrix adjust. Identities = 51/161 (31%), Positives = 69/161 (42%), Gaps = 20/161 (12%) Query: 107 SHGMGIPSISIMLHELIKLLYYARCSNVTIIRIGTSGGIGLE--PGTVVITEQAVD-TCF 163 S G+G PS SI + EL KL C T IR+GT GGI L+ G +VI A+ Sbjct: 92 STGIGGPSASIAMEEL-KL-----CGADTFIRVGTCGGIELDVKGGDIVIATGAIRMEGT 145 Query: 164 KAEFEQIVLGKRVIRKTDLNKKLVQELLLCSAELSEFTTVVGNTMCTLDFYEGQGRLDGA 223 E+ I DL V L+ +A+ +T+ G C FY GQ + Sbjct: 146 SKEYAPI----EFPAVADLE---VTNALVNAAKKLGYTSHAGVVQCKDAFY-GQHEPERM 197 Query: 224 LCSYTEKDKQAYLEAAYAAGVRNIEMESSVFAAMCSACGLQ 264 SY +K EA G + EMES+ S G++ Sbjct: 198 PVSYELLNK---WEAWKRLGTKASEMESAALFVAASHLGVR 235 >3MB8-A nrPDB Length = 279 Score = 35.0 bits (79), Expect = 0.046, Method: Compositional matrix adjust. Identities = 24/67 (35%), Positives = 33/67 (49%), Gaps = 9/67 (13%) Query: 97 MYKVGPVLSVSHGMGIPSISIMLHELIKLLYYARCSNVTIIRIGTSGGIG---LEPGTVV 153 +Y P+ +SHG+G P SI + EL L IIR GT G + L+ G V Sbjct: 58 VYDSQPITVISHGIGCPGTSIAIEELAYL------GAKVIIRAGTCGSLKPKTLKQGDVC 111 Query: 154 ITEQAVD 160 +T AV+ Sbjct: 112 VTYAAVN 118 >1VHW-A nrPDB Length = 253 Score = 33.5 bits (75), Expect = 0.13, Method: Compositional matrix adjust. Identities = 24/59 (40%), Positives = 33/59 (55%), Gaps = 7/59 (11%) Query: 98 YKVGPVLSVSHGMGIPSISIMLHELIKLLYYARCSNVTIIRIGTSGGI--GLEPGTVVI 154 YK + + HGMGIPS SI + ELIK + IIR+G+ G + G++ VVI Sbjct: 55 YKGRRISVMGHGMGIPSCSIYVTELIKDYGVKK-----IIRVGSCGAVNEGIKVRDVVI 108 >4TYM-A nrPDB Length = 258 Score = 33.1 bits (74), Expect = 0.16, Method: Compositional matrix adjust. Identities = 22/48 (45%), Positives = 29/48 (60%), Gaps = 5/48 (10%) Query: 98 YKVGPVLSVSHGMGIPSISIMLHELIKLLYYARCSNVTIIRIGTSGGI 145 YK V + GMG+PSISI ELI + Y + T+IR+GT+G I Sbjct: 74 YKGHRVSVMGTGMGMPSISIYARELI-VDYGVK----TLIRVGTAGAI 116 >1PR2-A nrPDB Length = 239 Score = 32.7 bits (73), Expect = 0.22, Method: Compositional matrix adjust. Identities = 32/96 (33%), Positives = 42/96 (43%), Gaps = 13/96 (13%) Query: 50 FGDVKFVCVGGSPSRMKAFIRCVGAELGLDCPGRDYPNICAGTDRYAMYKVGPVLSVSHG 109 F DV V + G P R K AE L+ R+ N+ YK + + HG Sbjct: 13 FADV--VLMPGDPLRAKYI-----AETFLE-DAREVNNVRGMLGFTGTYKGRKISVMGHG 64 Query: 110 MGIPSISIMLHELIKLLYYARCSNVTIIRIGTSGGI 145 MGIPS SI ELI + IIR+G+ G + Sbjct: 65 MGIPSCSIYTKELITDFGVKK-----IIRVGSCGAV 95 >4LDN-A nrPDB Length = 261 Score = 32.7 bits (73), Expect = 0.22, Method: Compositional matrix adjust. Identities = 37/119 (31%), Positives = 50/119 (42%), Gaps = 26/119 (21%) Query: 34 LYHFNLTTSRHNFP-ALFGDVKFVCVGGSPSRMKAFIRCVGAELGLDCPGRDYPNICAGT 92 LY +++T N P F D + + G P R K AE L+ N+ T Sbjct: 18 LYFQSMSTPHINAPLDAFADT--ILMPGDPLRAKLI-----AETYLE-------NVVQVT 63 Query: 93 DRYAM------YKVGPVLSVSHGMGIPSISIMLHELIKLLYYARCSNVTIIRIGTSGGI 145 D M +K + + HGMG PS SI HEL+ + N IRIG+ G I Sbjct: 64 DVRGMLGFTGEFKGRKISVMGHGMGAPSASIYFHELMTTY---KVKN--FIRIGSCGAI 117 >4LKR-A nrPDB Length = 256 Score = 32.3 bits (72), Expect = 0.24, Method: Compositional matrix adjust. Identities = 22/50 (44%), Positives = 26/50 (52%), Gaps = 6/50 (12%) Query: 95 YAMYKVGPVLSV-SHGMGIPSISIMLHELIKLLYYARCSNVTIIRIGTSG 143 Y Y G +SV HGMGI S+ + HELI R IIRIG+ G Sbjct: 70 YTGYYQGQRISVMGHGMGISSMVLYGHELINFFGVKR-----IIRIGSLG 114 >3OCC-A nrPDB Length = 239 Score = 32.0 bits (71), Expect = 0.31, Method: Compositional matrix adjust. Identities = 19/48 (39%), Positives = 25/48 (52%), Gaps = 5/48 (10%) Query: 98 YKVGPVLSVSHGMGIPSISIMLHELIKLLYYARCSNVTIIRIGTSGGI 145 YK + + HGMGIPS SI ELI + IIR+G+ G + Sbjct: 53 YKGRKISVMGHGMGIPSCSIYAKELITDFGVKK-----IIRVGSCGAV 95 >4M7W-A nrPDB Length = 258 Score = 32.0 bits (71), Expect = 0.38, Method: Compositional matrix adjust. Identities = 21/59 (35%), Positives = 26/59 (44%), Gaps = 5/59 (8%) Query: 85 YPNICAGTDRYAMYKVGPVLSVSHGMGIPSISIMLHELIKLLYYARCSNVTIIRIGTSG 143 Y N+ YK V GMG+PSI I HELI +IR+GT+G Sbjct: 62 YNNVRGMLGFTGTYKGKKVSVQGTGMGVPSIGIYSHELI-----TEFGVKNLIRVGTAG 115 >3UAY-A nrPDB Length = 235 Score = 31.6 bits (70), Expect = 0.41, Method: Compositional matrix adjust. Identities = 18/37 (48%), Positives = 25/37 (67%), Gaps = 5/37 (13%) Query: 109 GMGIPSISIMLHELIKLLYYARCSNVTIIRIGTSGGI 145 GMG+PSISI ++ELI+ Y + +IR+GT G I Sbjct: 63 GMGVPSISIYVNELIQ-SYGVK----NLIRVGTCGAI 94 >4LNH-A nrPDB Length = 266 Score = 31.6 bits (70), Expect = 0.43, Method: Compositional matrix adjust. Identities = 30/107 (28%), Positives = 52/107 (48%), Gaps = 15/107 (14%) Query: 55 FVCVGGSPSRMKAFIRCVGAELGLDCPGRDYPNICAGTDRYAMYKVGPVLSVSHGMGIPS 114 +V V G P R+ + + + L R+Y + G +YK + S G+G PS Sbjct: 39 YVIVCGEPDRVNRIVELMD-NVELLAENREY-RVFNG-----VYKGTTITICSTGIGAPS 91 Query: 115 ISIMLHELIKLLYYARCSNVTIIRIGTSGGI--GLEPGTVVITEQAV 159 + I + EL KL C +IR+G++G + ++ G +++ E AV Sbjct: 92 MIIAVEEL-KL-----CGATHVIRVGSAGAMQDHIQLGELIVAEGAV 132 >1JE0-A nrPDB Length = 236 Score = 30.8 bits (68), Expect = 0.80, Method: Compositional matrix adjust. Identities = 20/46 (43%), Positives = 29/46 (63%), Gaps = 7/46 (15%) Query: 101 GPVLSV-SHGMGIPSISIMLHELIKLLYYARCSNVTIIRIGTSGGI 145 G +S+ +HG+G PSI+I+L EL L +NV IR GT+G + Sbjct: 54 GETVSIATHGIGGPSIAIVLEELAML-----GANV-FIRYGTTGAL 93 >4DAO-A nrPDB Length = 253 Score = 30.4 bits (67), Expect = 1.1, Method: Compositional matrix adjust. Identities = 16/37 (43%), Positives = 23/37 (62%), Gaps = 5/37 (13%) Query: 109 GMGIPSISIMLHELIKLLYYARCSNVTIIRIGTSGGI 145 GMG+PSISI ++ELI+ +IR+G+ G I Sbjct: 83 GMGVPSISIYVNELIQ-----SYDVQNLIRVGSCGAI 114 >6F5I-A nrPDB Length = 233 Score = 30.0 bits (66), Expect = 1.2, Method: Compositional matrix adjust. Identities = 21/53 (39%), Positives = 29/53 (54%), Gaps = 5/53 (9%) Query: 98 YKVGPVLSVSHGMGIPSISIMLHELIKLLYYARCSNVTIIRIGTSGGIGLEPG 150 YK + + HGMGI S +I + ELIK Y + ++RIGT G I + G Sbjct: 52 YKGRGISLMGHGMGIASCTIYVTELIK-TYQVK----ELLRIGTCGAISPKVG 99 >6DZ3-A nrPDB Length = 297 Score = 30.0 bits (66), Expect = 1.2, Method: Compositional matrix adjust. Identities = 19/54 (35%), Positives = 30/54 (55%), Gaps = 5/54 (9%) Query: 126 LYY---ARCSNVTIIRIGTSGGIGLEPGTVV--ITEQAVDTCFKAEFEQIVLGK 174 LY+ A + T ++IG GG GL+ ++ TE+ VDT F + ++LGK Sbjct: 10 LYFQSMASGTTTTAVKIGIIGGTGLDDPEILEGRTEKYVDTPFGKPSDALILGK 63 >1P88-A nrPDB Length = 216 Score = 30.0 bits (66), Expect = 1.4, Method: Compositional matrix adjust. Identities = 18/68 (26%), Positives = 35/68 (51%), Gaps = 4/68 (5%) Query: 219 RLDGALCSYTEKDKQA--YLEAAYAAGVRNIEMESSVFAAMCSACGLQAAVVCVTLLNRL 276 RL GA +Y E++ L+ + G N++++ SV + +A + A + + R+ Sbjct: 110 RLGGAKITYLEQENYPPLRLQGGFTGG--NVDVDGSVSSQFLTALLMTAPLAPEDTVIRI 167 Query: 277 EGDQISSP 284 +GD +S P Sbjct: 168 KGDLVSKP 175 >6A9U-A nrPDB Length = 455 Score = 30.0 bits (66), Expect = 1.4, Method: Compositional matrix adjust. Identities = 17/49 (34%), Positives = 25/49 (51%), Gaps = 6/49 (12%) Query: 66 KAFIRCVGAELGLDCPGRDYPNICAGTDRYAMYKVGPVLSVSHGMGIPS 114 K + +G LGLD D P + RY KVG V+++ G+ IP+ Sbjct: 353 KLYPHYIGHNLGLDV--HDVPKVS----RYEPLKVGQVITIEPGLYIPN 395 >3FJZ-A nrPDB Length = 427 Score = 29.3 bits (64), Expect = 2.6, Method: Compositional matrix adjust. Identities = 18/68 (26%), Positives = 35/68 (51%), Gaps = 4/68 (5%) Query: 219 RLDGALCSYTEKDKQA--YLEAAYAAGVRNIEMESSVFAAMCSACGLQAAVVCVTLLNRL 276 RL GA +Y E++ L+ + G N++++ SV + +A + A + + R+ Sbjct: 134 RLGGAKITYLEQENYPPLRLQGGFTGG--NVDVDGSVSSQFLTALLMTAPLAPEDTVIRI 191 Query: 277 EGDQISSP 284 +GD +S P Sbjct: 192 KGDLVSKP 199 >1NRK-A nrPDB Length = 328 Score = 29.3 bits (64), Expect = 2.6, Method: Compositional matrix adjust. Identities = 17/56 (30%), Positives = 25/56 (44%), Gaps = 8/56 (14%) Query: 207 TMCTLDFYEGQGRLDGALCSYTEKDKQAYLEAAYAAGVRNIEMESSVFAAMCSACG 262 T+ TLD D AL + T D + Y++ A V + + + AA C A G Sbjct: 23 TLMTLD--------DWALATITGADSEKYMQGQVTADVSQMAEDQHLLAAHCDAKG 70 >5VM8-A nrPDB Length = 249 Score = 28.9 bits (63), Expect = 3.0, Method: Compositional matrix adjust. Identities = 15/47 (31%), Positives = 22/47 (46%), Gaps = 9/47 (19%) Query: 132 SNVTIIRIGTSGGIGLEPGTVVITEQAVDTCFKAEFEQIVLGKRVIR 178 S + +G GG TEQ F+A F+ + LGKR++R Sbjct: 192 SGAIVFMVGPEGGW---------TEQEEQQAFEAGFQAVTLGKRILR 229 >1NXZ-A nrPDB Length = 246 Score = 27.3 bits (59), Expect = 8.5, Method: Compositional matrix adjust. Identities = 17/61 (27%), Positives = 29/61 (47%), Gaps = 9/61 (14%) Query: 139 IGTSGGIGLEPGTVVITEQAVDTCFKAEFEQIVLGKRVIRKTDLNKKLVQELLLCSAELS 198 IG+ GG+ + Q + + F +I+LGKRV+R + + L +C +L Sbjct: 193 IGSEGGL---------SAQEIAQTEQQGFTEILLGKRVLRTETASLAAISALQICFGDLG 243 Query: 199 E 199 E Sbjct: 244 E 244 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 3EUF-A nrPDB 449 e-127 3KUK-A nrPDB 437 e-123 3P0E-A nrPDB 390 e-109 4TXN-A nrPDB 359 1e-99 5CYF-A nrPDB 353 6e-98 1U1E-A nrPDB 252 2e-67 4I2V-A nrPDB 250 6e-67 3PNS-A nrPDB 249 2e-66 4R2W-A nrPDB 240 7e-64 4R31-A nrPDB 235 2e-62 3BJE-A nrPDB 180 1e-45 1ODL-A nrPDB 179 1e-45 4M3N-A nrPDB 169 1e-42 2ISC-A nrPDB 144 4e-35 3TL6-A nrPDB 124 3e-29 Sequences not found previously or not previously below threshold: 3UAY-A nrPDB 134 5e-32 1PR2-A nrPDB 127 7e-30 3OCC-A nrPDB 125 2e-29 3QPB-A nrPDB 124 5e-29 4DAO-A nrPDB 120 6e-28 4M7W-A nrPDB 119 1e-27 1VHW-A nrPDB 115 2e-26 6F5I-A nrPDB 110 9e-25 4LDN-A nrPDB 109 2e-24 1JE0-A nrPDB 109 2e-24 4TYM-A nrPDB 108 2e-24 4LNH-A nrPDB 104 5e-23 4LKR-A nrPDB 96 2e-20 3MB8-A nrPDB 86 1e-17 3EMV-A nrPDB 82 3e-16 5ZNI-A nrPDB 75 6e-14 1NW4-A nrPDB 75 6e-14 6IF8-A nrPDB 49 3e-06 4G41-A nrPDB 46 2e-05 4WKO-A nrPDB 45 3e-05 1ZOS-A nrPDB 45 4e-05 4KN5-A nrPDB 45 5e-05 4WKB-A nrPDB 41 5e-04 5UE1-A nrPDB 36 0.020 4YML-A nrPDB 35 0.046 5DK6-A nrPDB 34 0.067 1TQY-B nrPDB 34 0.080 2J98-A nrPDB 31 0.98 1O4S-A nrPDB 30 1.1 3C8E-A nrPDB 29 1.8 3LGS-A nrPDB 29 2.7 3EEI-A nrPDB 28 5.9 6DZ3-A nrPDB 28 7.1 >3EUF-A nrPDB Length = 328 Score = 449 bits (1154), Expect = e-127, Method: Composition-based stats. Identities = 310/310 (100%), Positives = 310/310 (100%) Query: 1 MAATGANAEKAESHNDCPVRLLNPNIAKMKEDILYHFNLTTSRHNFPALFGDVKFVCVGG 60 MAATGANAEKAESHNDCPVRLLNPNIAKMKEDILYHFNLTTSRHNFPALFGDVKFVCVGG Sbjct: 19 MAATGANAEKAESHNDCPVRLLNPNIAKMKEDILYHFNLTTSRHNFPALFGDVKFVCVGG 78 Query: 61 SPSRMKAFIRCVGAELGLDCPGRDYPNICAGTDRYAMYKVGPVLSVSHGMGIPSISIMLH 120 SPSRMKAFIRCVGAELGLDCPGRDYPNICAGTDRYAMYKVGPVLSVSHGMGIPSISIMLH Sbjct: 79 SPSRMKAFIRCVGAELGLDCPGRDYPNICAGTDRYAMYKVGPVLSVSHGMGIPSISIMLH 138 Query: 121 ELIKLLYYARCSNVTIIRIGTSGGIGLEPGTVVITEQAVDTCFKAEFEQIVLGKRVIRKT 180 ELIKLLYYARCSNVTIIRIGTSGGIGLEPGTVVITEQAVDTCFKAEFEQIVLGKRVIRKT Sbjct: 139 ELIKLLYYARCSNVTIIRIGTSGGIGLEPGTVVITEQAVDTCFKAEFEQIVLGKRVIRKT 198 Query: 181 DLNKKLVQELLLCSAELSEFTTVVGNTMCTLDFYEGQGRLDGALCSYTEKDKQAYLEAAY 240 DLNKKLVQELLLCSAELSEFTTVVGNTMCTLDFYEGQGRLDGALCSYTEKDKQAYLEAAY Sbjct: 199 DLNKKLVQELLLCSAELSEFTTVVGNTMCTLDFYEGQGRLDGALCSYTEKDKQAYLEAAY 258 Query: 241 AAGVRNIEMESSVFAAMCSACGLQAAVVCVTLLNRLEGDQISSPRNVLSEYQQRPQRLVS 300 AAGVRNIEMESSVFAAMCSACGLQAAVVCVTLLNRLEGDQISSPRNVLSEYQQRPQRLVS Sbjct: 259 AAGVRNIEMESSVFAAMCSACGLQAAVVCVTLLNRLEGDQISSPRNVLSEYQQRPQRLVS 318 Query: 301 YFIKKKLSKA 310 YFIKKKLSKA Sbjct: 319 YFIKKKLSKA 328 >3KUK-A nrPDB Length = 309 Score = 437 bits (1124), Expect = e-123, Method: Composition-based stats. Identities = 249/310 (80%), Positives = 275/310 (88%), Gaps = 1/310 (0%) Query: 1 MAATGANAEKAESHNDCPVRLLNPNIAKMKEDILYHFNLTTSRHNFPALFGDVKFVCVGG 60 MA+T A EK E HND V+L NP+IA MKEDILYHF+L+TS H+FPA+FGDVKFVCVGG Sbjct: 1 MASTAAETEKPEDHNDL-VQLCNPHIAAMKEDILYHFSLSTSTHDFPAMFGDVKFVCVGG 59 Query: 61 SPSRMKAFIRCVGAELGLDCPGRDYPNICAGTDRYAMYKVGPVLSVSHGMGIPSISIMLH 120 SPSRMKAFI+ V ELG PG DYPNIC GTDRYAM+KVGPVLSVSHGMG+PSI+IMLH Sbjct: 60 SPSRMKAFIKYVAMELGFAHPGADYPNICEGTDRYAMFKVGPVLSVSHGMGVPSIAIMLH 119 Query: 121 ELIKLLYYARCSNVTIIRIGTSGGIGLEPGTVVITEQAVDTCFKAEFEQIVLGKRVIRKT 180 ELIKLLY+A CS VT+IRIGTSGGIGLEPG+VVIT QAVD CFK EFEQIVLGKR +R T Sbjct: 120 ELIKLLYHAHCSGVTLIRIGTSGGIGLEPGSVVITRQAVDPCFKPEFEQIVLGKREVRNT 179 Query: 181 DLNKKLVQELLLCSAELSEFTTVVGNTMCTLDFYEGQGRLDGALCSYTEKDKQAYLEAAY 240 DL+++LVQEL CSAEL EF TVVGNTMCTLDFYEGQGRLDGALCSYTEKDKQ YL AAY Sbjct: 180 DLDEQLVQELARCSAELGEFPTVVGNTMCTLDFYEGQGRLDGALCSYTEKDKQDYLRAAY 239 Query: 241 AAGVRNIEMESSVFAAMCSACGLQAAVVCVTLLNRLEGDQISSPRNVLSEYQQRPQRLVS 300 AAG+RNIEME+SVFAAMC+ACGL+AAVVCVTLLNRLEGDQISSP +VL+EYQQRPQRLV Sbjct: 240 AAGIRNIEMEASVFAAMCNACGLRAAVVCVTLLNRLEGDQISSPHDVLAEYQQRPQRLVG 299 Query: 301 YFIKKKLSKA 310 FIKK+L +A Sbjct: 300 QFIKKRLMQA 309 >3P0E-A nrPDB Length = 297 Score = 390 bits (1000), Expect = e-109, Method: Composition-based stats. Identities = 191/289 (66%), Positives = 231/289 (79%) Query: 19 VRLLNPNIAKMKEDILYHFNLTTSRHNFPALFGDVKFVCVGGSPSRMKAFIRCVGAELGL 78 V + NP + M EDILYH +L T HN PA+FGDVKFVCVGGSP+RMKAF + ELG Sbjct: 8 VHVKNPYLDLMDEDILYHLDLGTKTHNLPAMFGDVKFVCVGGSPNRMKAFALFMHKELGF 67 Query: 79 DCPGRDYPNICAGTDRYAMYKVGPVLSVSHGMGIPSISIMLHELIKLLYYARCSNVTIIR 138 + D +ICAGTDRY MYK GPVL++SHGMGIPSISIMLHELIKLL++ARC +VTIIR Sbjct: 68 EEAEEDIKDICAGTDRYCMYKTGPVLAISHGMGIPSISIMLHELIKLLHHARCCDVTIIR 127 Query: 139 IGTSGGIGLEPGTVVITEQAVDTCFKAEFEQIVLGKRVIRKTDLNKKLVQELLLCSAELS 198 IGTSGGIG+ PGTVVIT+ AVD+ FK FEQ++L V R T+L+K+L +EL CS E+ Sbjct: 128 IGTSGGIGIAPGTVVITDIAVDSFFKPRFEQVILDNIVTRSTELDKELSEELFNCSKEIP 187 Query: 199 EFTTVVGNTMCTLDFYEGQGRLDGALCSYTEKDKQAYLEAAYAAGVRNIEMESSVFAAMC 258 F T+VG+TMCT DFYEGQGRLDGALCS++ + K YL+ A+ AGVRNIEMES+VFAAMC Sbjct: 188 NFPTLVGHTMCTYDFYEGQGRLDGALCSFSREKKLDYLKRAFKAGVRNIEMESTVFAAMC 247 Query: 259 SACGLQAAVVCVTLLNRLEGDQISSPRNVLSEYQQRPQRLVSYFIKKKL 307 CGL+AAVVCVTLL+RL+ DQI+ P +VL EYQQRPQ L+S FI+++L Sbjct: 248 GLCGLKAAVVCVTLLDRLDCDQINLPHDVLVEYQQRPQLLISNFIRRRL 296 >4TXN-A nrPDB Length = 296 Score = 359 bits (920), Expect = 1e-99, Method: Composition-based stats. Identities = 125/287 (43%), Positives = 186/287 (64%), Gaps = 4/287 (1%) Query: 21 LLNPNIAKMKEDILYHFNLTTSRHNFPALFGDVKFVCVGGSPSRMKAFIRCVGAELGLDC 80 ++N +++++ ED+ +HF TT +F FGDVKFVCV GS R+ F + GL Sbjct: 7 IVNSHLSELDEDVFHHFGFTTKSFDFKEKFGDVKFVCVCGSSGRIHNFAISMAKLAGLAL 66 Query: 81 PGRDYPNICAGTDRYAMYKVGPVLSVSHGMGIPSISIMLHELIKLLYYARCSNVTIIRIG 140 P NI R+ +YKV +L HGMGIPS IMLHE+ KLL+YA C +V IR+G Sbjct: 67 P---VENIAGSHARFVLYKVDHILFADHGMGIPSALIMLHEVTKLLHYAGCKDVLFIRLG 123 Query: 141 TSGGIGLEPGTVVITEQAVDTCFKAEFEQIVLGKRVIRKTDLNKKLVQELLLCSAELS-E 199 TSGG+G++PGT+V++++ V+T + E +LGK V R+T ++ V EL S LS E Sbjct: 124 TSGGLGVKPGTIVLSDRCVNTKLEPYNELCILGKPVRRQTIVDLNTVNELKKLSENLSLE 183 Query: 200 FTTVVGNTMCTLDFYEGQGRLDGALCSYTEKDKQAYLEAAYAAGVRNIEMESSVFAAMCS 259 + VVG T+ DFYE QGRLDG++C++++++K A+L++AY G+RN+EME + + C Sbjct: 184 CSVVVGGTIAANDFYEEQGRLDGSICTFSKEEKLAFLQSAYEHGIRNMEMEGTAITSHCY 243 Query: 260 ACGLQAAVVCVTLLNRLEGDQISSPRNVLSEYQQRPQRLVSYFIKKK 306 G +A +VCVT +NRLEGDQI+ + + + QRP +LV ++K+ Sbjct: 244 LTGHRAILVCVTAVNRLEGDQITISTDEFTLFAQRPGQLVGEYLKRN 290 >5CYF-A nrPDB Length = 296 Score = 353 bits (905), Expect = 6e-98, Method: Composition-based stats. Identities = 114/287 (39%), Positives = 184/287 (64%), Gaps = 4/287 (1%) Query: 21 LLNPNIAKMKEDILYHFNLTTSRHNFPALFGDVKFVCVGGSPSRMKAFIRCVGAELGLDC 80 ++N +++++ ED+ +HF TT +F FGDVKFVCV GS R+ F + GL Sbjct: 7 IVNSHLSELDEDVFHHFGFTTKSFDFKEKFGDVKFVCVCGSSGRIHNFAISMAKLAGLAL 66 Query: 81 PGRDYPNICAGTDRYAMYKVGPVLSVSHGMGIPSISIMLHELIKLLYYARCSNVTIIRIG 140 P NI R+ +YKV +L HG+GIPS I++HE+ KLLYYA C +V IR+G Sbjct: 67 P---VENIAGSHARFVLYKVDHILFADHGIGIPSTLILMHEVTKLLYYAGCKDVLFIRLG 123 Query: 141 TSGGIGLEPGTVVITEQAVDTCFKAEFEQIVLGKRVIRKTDLNKKLVQELLLCSAELS-E 199 TS G+G++PGT+V++++ V+T + E +LGK V R+T ++ V EL S LS + Sbjct: 124 TSDGLGVKPGTIVLSDRCVNTKLEPYNELCILGKPVRRQTKVDSNAVNELKKLSENLSLK 183 Query: 200 FTTVVGNTMCTLDFYEGQGRLDGALCSYTEKDKQAYLEAAYAAGVRNIEMESSVFAAMCS 259 + VVG T+ DFYE GRL+G++C++++++K A+L++ Y G+RN+EME + + C+ Sbjct: 184 CSVVVGGTITANDFYEELGRLNGSICTFSKEEKLAFLQSVYDHGIRNMEMEGAAITSHCN 243 Query: 260 ACGLQAAVVCVTLLNRLEGDQISSPRNVLSEYQQRPQRLVSYFIKKK 306 G +A +VCVT++NRLE D++++ + ++Q P +LV ++K+ Sbjct: 244 LTGHRAILVCVTVVNRLETDEVTTSTDEFKLFEQLPGQLVGEYLKRN 290 >1U1E-A nrPDB Length = 256 Score = 252 bits (642), Expect = 2e-67, Method: Composition-based stats. Identities = 71/283 (25%), Positives = 116/283 (40%), Gaps = 30/283 (10%) Query: 27 AKMKEDILYHFNLTTSRHNFPALFGDVKFVCVGGSPSRMKAFIRCVGAELGLDCPGRDYP 86 + M + ++H LT + V G P R++ + + L R++ Sbjct: 2 SHMSKSDVFHLGLTKND------LQGATLAIVPGDPDRVEKIAALMDKPVKLA-SHREFT 54 Query: 87 NICAGTDRYAMYKVGPVLSVSHGMGIPSISIMLHELIKLLYYARCSNVTIIRIGTSGGI- 145 A D PV+ S G+G PS SI + EL +L T +RIGT+G I Sbjct: 55 TWRAELD------GKPVIVCSTGIGGPSTSIAVEELAQLGIR------TFLRIGTTGAIQ 102 Query: 146 -GLEPGTVVITEQAVDTCFKAEFEQIVLGKRVIRKTDLNKKLVQELLLCSAELSEFTTVV 204 + G V++T +V A L + + LV+ +A+ TT V Sbjct: 103 PHINVGDVLVTTASVR-LDGASLHFAPLEFPAVADFECTTALVE-----AAKSIGATTHV 156 Query: 205 GNTMCTLDFYEGQGRLDGALCSYTEKDKQAYLEAAYAAGVRNIEMESSVFAAMCSACGLQ 264 G T + FY GQ R D + + +E A GV N EMES+ MC++ GL+ Sbjct: 157 GVTASSDTFYPGQERYD-TYSGRVVRHFKGSMEEWQAMGVMNYEMESATLLTMCASQGLR 215 Query: 265 AAVVCVTLLNRLEGDQISSPRNVLSEYQQRPQRLVSYFIKKKL 307 A +V ++NR + Q + + + ++V ++ L Sbjct: 216 AGMVAGVIVNRTQ--QEIPNAETMKQTESHAVKIVVEAARRLL 256 >4I2V-A nrPDB Length = 253 Score = 250 bits (637), Expect = 6e-67, Method: Composition-based stats. Identities = 69/281 (24%), Positives = 113/281 (40%), Gaps = 30/281 (10%) Query: 29 MKEDILYHFNLTTSRHNFPALFGDVKFVCVGGSPSRMKAFIRCVGAELGLDCPGRDYPNI 88 M + ++H LT + V G P R++ + + + L R++ + Sbjct: 1 MAKSDVFHLGLTKND------LQGATLAIVPGDPQRVEKIAKLMDNPVHLA-SHREFTSW 53 Query: 89 CAGTDRYAMYKVGPVLSVSHGMGIPSISIMLHELIKLLYYARCSNVTIIRIGTSGGI--G 146 A D A V+ S G+G PS SI + EL +L T +RIGT+G I Sbjct: 54 RAELDGKA------VIVCSTGIGGPSTSIAVEELAQLGVR------TFLRIGTTGAIQPH 101 Query: 147 LEPGTVVITEQAVDTCFKAEFEQIVLGKRVIRKTDLNKKLVQELLLCSAELSEFTTVVGN 206 + G V++T AV A + + LV +A+ TT +G Sbjct: 102 INVGDVLVTTAAVR-LDGASLHFAPMEFPAVADFSCTTALVN-----AAKSVGATTHIGI 155 Query: 207 TMCTLDFYEGQGRLDGALCSYTEKDKQAYLEAAYAAGVRNIEMESSVFAAMCSACGLQAA 266 T + FY GQ R D + + +E + GV N EMES+ MC++ GL+A Sbjct: 156 TASSDTFYPGQERYD-TFSGRVVRHFKGSMEEWQSMGVMNYEMESATLLTMCASQGLRAG 214 Query: 267 VVCVTLLNRLEGDQISSPRNVLSEYQQRPQRLVSYFIKKKL 307 +V ++NR + Q + + ++V + L Sbjct: 215 MVAGVIVNRTQ--QEIPNEETMKATESHAVKIVVEAARHLL 253 >3PNS-A nrPDB Length = 261 Score = 249 bits (634), Expect = 2e-66, Method: Composition-based stats. Identities = 67/276 (24%), Positives = 112/276 (40%), Gaps = 30/276 (10%) Query: 34 LYHFNLTTSRHNFPALFGDVKFVCVGGSPSRMKAFIRCVGAELGLDCPGRDYPNICAGTD 93 ++H +T + N + G P+R++ + + L R+Y A D Sbjct: 13 VFHLGVTEADLN------GATLAIIPGDPARVQKIAELMDNPVFLA-SHREYTVYRAELD 65 Query: 94 RYAMYKVGPVLSVSHGMGIPSISIMLHELIKLLYYARCSNVTIIRIGTSGGI--GLEPGT 151 V+ S G+G PS SI + EL +L T +R+GT+G I + G Sbjct: 66 ------GQSVVVCSTGIGGPSTSIAVEELAQLGVR------TFLRVGTTGAIQPHVNVGD 113 Query: 152 VVITEQAVDTCFKAEFEQIVLGKRVIRKTDLNKKLVQELLLCSAELSEFTTVVGNTMCTL 211 +++T +V A + + D V + +A+ S T +G T + Sbjct: 114 MIVTTGSVR-LDGASLHFAPMEFPAVPDFD-----VATAMKAAAQESGATVHMGVTASSD 167 Query: 212 DFYEGQGRLDGALCSYTEKDKQAYLEAAYAAGVRNIEMESSVFAAMCSACGLQAAVVCVT 271 FY GQ R D + Q ++ GV N EMES+ MC++ GL+A V Sbjct: 168 TFYPGQERYD-TFTGRVVRRFQGSMKEWQDMGVLNFEMESATLLTMCASSGLKAGCVAGV 226 Query: 272 LLNRLEGDQISSPRNVLSEYQQRPQRLVSYFIKKKL 307 ++NR + + L E + R ++V +K L Sbjct: 227 IINRTQKE--IPDHATLKETEARSIKVVVEAARKML 260 >4R2W-A nrPDB Length = 252 Score = 240 bits (611), Expect = 7e-64, Method: Composition-based stats. Identities = 67/278 (24%), Positives = 107/278 (38%), Gaps = 30/278 (10%) Query: 33 ILYHFNLTTSRHNFPALFGDVKFVCVGGSPSRMKAFIRCVGAELGLDCPGRDYPNICAGT 92 ++H LT A+ V G P R+K + L R+Y + A Sbjct: 3 DVFHLGLTK------AMLDGATLAIVPGDPERVKRIAELMDNATFLA-SHREYTSYLAYA 55 Query: 93 DRYAMYKVGPVLSVSHGMGIPSISIMLHELIKLLYYARCSNVTIIRIGTSGGI--GLEPG 150 D PV+ S G+G PS SI + EL +L T +R+GT+G I + G Sbjct: 56 D------GKPVVICSTGIGGPSTSIAVEELAQLGVN------TFLRVGTTGAIQPHVNVG 103 Query: 151 TVVITEQAVDTCFKAEFEQIVLGKRVIRKTDLNKKLVQELLLCSAELSEFTTVVGNTMCT 210 V++T+ +V A + + + +V E +G T + Sbjct: 104 DVIVTQASVR-LDGASLHFAPMEFPAVANFECTTAMVAACRDAGVEP-----HIGVTASS 157 Query: 211 LDFYEGQGRLDGALCSYTEKDKQAYLEAAYAAGVRNIEMESSVFAAMCSACGLQAAVVCV 270 FY GQ R D + + ++ GV N EMES+ MC+ G +AA V Sbjct: 158 DTFYPGQERYD-TVTGRVTRRFAGSMKEWQDMGVLNYEMESATLFTMCATQGWRAACVAG 216 Query: 271 TLLNRLEGDQISSPRNVLSEYQQRPQRLVSYFIKKKLS 308 ++NR + Q + + + +V KK L+ Sbjct: 217 VIVNRTQ--QEIPDEATMKKTEVSAVSIVVAAAKKLLA 252 >4R31-A nrPDB Length = 279 Score = 235 bits (599), Expect = 2e-62, Method: Composition-based stats. Identities = 72/288 (25%), Positives = 112/288 (38%), Gaps = 32/288 (11%) Query: 23 NPNIAKMKEDILYHFNLTTSRHNFPALFGDVKFVCVGGSPSRMKAFIRCVGAELGLDCPG 82 N M E ++H LT A+ K + G P+R + + + L Sbjct: 17 NLYFQSMSE--VFHLGLTK------AMLKGAKIAVIPGDPARSERIAQRMDKPEFLASS- 67 Query: 83 RDYPNICAGTDRYAMYKVGPVLSVSHGMGIPSISIMLHELIKLLYYARCSNVTIIRIGTS 142 R++ + + PV+ S G+G PS+SI + EL +L T +RIGT+ Sbjct: 68 REFTSWLGYL------ENEPVVVCSTGIGGPSVSICVEELAQLG------VGTFLRIGTT 115 Query: 143 GGIG--LEPGTVVITEQAVDTCFKAEFEQIVLGKRVIRKTDLNKKLVQELLLCSAELSEF 200 G I + G V++T AV A L + L +A Sbjct: 116 GAIQPYINVGDVLVTTGAVR-LDGASRHFAPLEYPAVADFSCT-----NALYSAAVAQGI 169 Query: 201 TTVVGNTMCTLDFYEGQGRLDGALCSYTEKDKQAYLEAAYAAGVRNIEMESSVFAAMCSA 260 T VG T + FY GQ R D Q L+ V N EMES+ MC+A Sbjct: 170 TPYVGITASSDTFYPGQERYD-TFSGKVYPAYQGSLKQWQDLNVMNYEMESATLFTMCAA 228 Query: 261 CGLQAAVVCVTLLNRLEGDQISSPRNVLSEYQQRPQRLVSYFIKKKLS 308 GL+A +V ++NR + Q + +Q+ +V ++ +S Sbjct: 229 LGLKAGMVAGVIVNRTQ--QEIPNEATIKSTEQKAVAVVIEAARRLIS 274 >3BJE-A nrPDB Length = 349 Score = 180 bits (455), Expect = 1e-45, Method: Composition-based stats. Identities = 66/310 (21%), Positives = 111/310 (35%), Gaps = 65/310 (20%) Query: 53 VKFVCVGGSPSRMKAFIRCVGAELGLDCPGRDYPNICAGTDRYAMYKVGPVLSVSHGMGI 112 + G P R+ + RD+ I T YK PV +S GMG+ Sbjct: 43 ADRIIFVGDPGRVDVISGYFDKDS--IRASRDHREIRFAT---GTYKGTPVTVISTGMGV 97 Query: 113 PSISIMLHELIKLLYYA----------------------RCSNVTIIRIGTSGGI--GLE 148 +I I+L+E+ L Y S + IIR+GT G + Sbjct: 98 DNIEIVLNEIHALKEYDMERGQWRHRKGDADAPSAGPFFDPSTMKIIRLGTCGSPAESVP 157 Query: 149 PGTVVITEQAVD---------------TCFKAEFEQIVLGKRVIRKTDLNKKLVQELL-- 191 P + +T A+ + + E +IV + +R D+ + + Sbjct: 158 PLALAVTRHAIGMDNTSLYYSAGTRETSKDQQEIRRIVREQTGLRAIDIYTSMAHPNITK 217 Query: 192 -LCSA----------ELSEFTTVVGNTMCTLDFYEGQGRLDGALCSY----TEKDKQAYL 236 +C+A E + V+G T FY QGR G + ++ L Sbjct: 218 SICAACDAHNAATGSEADKQQYVIGTTATASGFYGCQGRRVGRFMKHLTVPNMVEELGSL 277 Query: 237 EAAYAAGVR---NIEMESSVFAAMCSACGLQAAVVCVTLLNRLEGDQISSPRNVLSEYQQ 293 + + GV NIEME+S + G QA CV + R+ G++ + L + Sbjct: 278 KFNLSNGVEVVTNIEMETSAICYLSDMLGYQAGAACVVVSKRV-GEKKMFLGDQLDAAMK 336 Query: 294 RPQRLVSYFI 303 R +++ + Sbjct: 337 RCIKIILEAL 346 >1ODL-A nrPDB Length = 235 Score = 179 bits (453), Expect = 1e-45, Method: Composition-based stats. Identities = 60/255 (23%), Positives = 101/255 (39%), Gaps = 40/255 (15%) Query: 53 VKFVCVGGSPSRMKAFIRCVGAELGLDCPGR--DYPNICAGTDRYAMYKVGPVLSVSHGM 110 + V + G P R + + L P R D+ + T +YK PV + GM Sbjct: 14 AERVLLPGDPGRAEWIAK-----TFLQNPRRYNDHRGLWGYT---GLYKGVPVSVQTTGM 65 Query: 111 GIPSISIMLHELIKLLYYARCSNVTIIRIGTSGGIG--LEPGTVVITEQAVDTCFKAEFE 168 G PS +I++ EL++L ++R+GT+G L PG +++ + AV Sbjct: 66 GTPSAAIVVEELVRL------GARVLVRVGTAGAASSDLAPGELIVAQGAV--PLDGTTR 117 Query: 169 QIVLGKRVIRKTDLNKKLVQELLLCSAELSEFTTVVGNTMCTLDFYEGQGRLDGALCSYT 228 Q + G+ D V L AE + VG FY + T Sbjct: 118 QYLEGRPYAPVPDPE---VFRALWRRAEALGYPHRVGLVASEDAFY-----------ATT 163 Query: 229 EKDKQAYLEAAYAAGVRNIEMESSVFAAMCSACGLQAAVVCVTLLNRLEGDQISSPRNVL 288 ++ +A+ GV EME+S + G++ + + + NR+ GD +P VL Sbjct: 164 PEEARAWARY----GVLAFEMEASALFLLGRMRGVRTGAI-LAVSNRI-GDPELAPPEVL 217 Query: 289 SEYQQRPQRLVSYFI 303 E +R + + Sbjct: 218 QEGVRRMVEVALEAV 232 >4M3N-A nrPDB Length = 254 Score = 169 bits (427), Expect = 1e-42, Method: Composition-based stats. Identities = 57/245 (23%), Positives = 93/245 (37%), Gaps = 38/245 (15%) Query: 53 VKFVCVGGSPSRMKAFIRCVGAELGLDCP--GRDYPNICAGTDRYAMYKVGPVLSVSHGM 110 + + + G P R K E L+ P N+ T YK V GM Sbjct: 35 AEAILLPGDPLRAKYIA-----ENFLENPVLYNQVRNMFGYT---GTYKGKRVSVQGTGM 86 Query: 111 GIPSISIMLHELIKLLYYARCSNVTIIRIGTSGGIG--LEPGTVVITEQAVDTCFKAEFE 168 GIPS SI +HEL++ T+IR+GT+G I L+ +VI + A Sbjct: 87 GIPSASIYIHELVQFY-----GCKTLIRVGTAGAITERLKLRDLVIAQAACTDSSINNLR 141 Query: 169 QIVLGKRVIRKTDLNKKLVQELLLCSAELSEFTTVVGNTMCTLDFYEGQGRLDGALCSYT 228 I DL ++ ++ A+ VGN + T FY Q + Sbjct: 142 FAGQNYAPIATFDLLRRAYEQ-----AQSRGMPVHVGNVLSTDTFYHDQPNPYQLWAQF- 195 Query: 229 EKDKQAYLEAAYAAGVRNIEMESSVFAAMCSACGLQAAVVCVTLLNRLEGDQISSPRNVL 288 GV +EME++ + + G+QA + +T+ + L + ++P+ Sbjct: 196 --------------GVLAVEMEAAGLYTLAAKFGVQALCI-LTISDHLITGEKTTPQERQ 240 Query: 289 SEYQQ 293 + Q Sbjct: 241 ETFDQ 245 >2ISC-A nrPDB Length = 239 Score = 144 bits (363), Expect = 4e-35, Method: Composition-based stats. Identities = 58/252 (23%), Positives = 89/252 (35%), Gaps = 36/252 (14%) Query: 44 HNFPALFGDVKFVCVGGSPSRMKAFIRCVGAELGLDCPGRDYPNICAGTDRY-AMYKVGP 102 HN + + V + G P R K E L+ P N G Y YK P Sbjct: 4 HNSAQVGDFAETVLMCGDPLRAKLIA-----ETYLENP--KLVNNVRGIQGYTGTYKGKP 56 Query: 103 VLSVSHGMGIPSISIMLHELIKLLYYARCSNVTIIRIGTSGGIGLEPG--TVVITEQAVD 160 + + HGMG+PSI I EL Y+ TIIR+GT G I ++ +VI A Sbjct: 57 ISVMGHGMGLPSICIYAEEL-----YSTYKVKTIIRVGTCGAIDMDIHTRDIVIFTSAGT 111 Query: 161 TCFKAEFEQIVLGKRVIRKTDLNKKLVQELLLCSAELSEFTTVVGNTMCTLDFYEGQGRL 220 + D+ LV +A+ VG T FY Q L Sbjct: 112 NSKINRIRFMDHDYPATASFDVVCALVD-----AAKELNIPAKVGKGFSTDLFYNPQTEL 166 Query: 221 DGALCSYTEKDKQAYLEAAYAAGVRNIEMESSVFAAMCSACGLQAAVVCVTLLNRLEGDQ 280 + + +EMES+ + G +A +C T+ + + + Sbjct: 167 AQLMNKFH---------------FLAVEMESAGLFPIADLYGARAGCIC-TVSDHILHHE 210 Query: 281 ISSPRNVLSEYQ 292 ++ + +Q Sbjct: 211 ETTAEERQNSFQ 222 >3UAY-A nrPDB Length = 235 Score = 134 bits (336), Expect = 5e-32, Method: Composition-based stats. Identities = 48/243 (19%), Positives = 84/243 (34%), Gaps = 34/243 (13%) Query: 53 VKFVCVGGSPSRMKAFIRCVGAELGLDCPGRDYPNICAGTDRYAMYKVGPVLSVSHGMGI 112 + + + G P R K ++ Y N+ YK V GMG+ Sbjct: 13 AESILLPGDPLRAKYIAETFLEDVTC------YNNVRGMLGFTGTYKGKRVSVQGTGMGV 66 Query: 113 PSISIMLHELIKLLYYARCSNVTIIRIGTSGGIG--LEPGTVVITEQAVDTCFKAEFEQI 170 PSISI ++ELI+ +IR+GT G I ++ V+I A Sbjct: 67 PSISIYVNELIQ-----SYGVKNLIRVGTCGAIQKDVKVRDVIIAMTACTDSNMNRLTFP 121 Query: 171 VLGKRVIRKTDLNKKLVQELLLCSAELSEFTTVVGNTMCTLDFYEGQGRLDGALCSYTEK 230 DL KK + VGN + FY + Sbjct: 122 GFDFAPAANFDLLKKAYD-----AGTEKGLHVRVGNVLTADVFY---------------R 161 Query: 231 DKQAYLEAAYAAGVRNIEMESSVFAAMCSACGLQAAVVCVTLLNRLEGDQISSPRNVLSE 290 + ++ GV +EME++ + + G+ A V +T+ N + + ++ + Sbjct: 162 ESMDMVKKLGDYGVLAVEMETTALYTLAAKYGVNALSV-LTVSNHIFTGEETTSEERQTT 220 Query: 291 YQQ 293 + + Sbjct: 221 FNE 223 >1PR2-A nrPDB Length = 239 Score = 127 bits (318), Expect = 7e-30, Method: Composition-based stats. Identities = 50/250 (20%), Positives = 83/250 (33%), Gaps = 34/250 (13%) Query: 44 HNFPALFGDVKFVCVGGSPSRMKAFIRCVGAELGLDCPGRDYPNICAGTDRYAMYKVGPV 103 H + V + G P R K + R+ N+ YK + Sbjct: 5 HINAEMGDFADVVLMPGDPLRAKYIAETFLEDA------REVNNVRGMLGFTGTYKGRKI 58 Query: 104 LSVSHGMGIPSISIMLHELIKLLYYARCSNVTIIRIGTSGG--IGLEPGTVVITEQAVDT 161 + HGMGIPS SI ELI IIR+G+ G ++ VVI A Sbjct: 59 SVMGHGMGIPSCSIYTKELI-----TDFGVKKIIRVGSCGAVLPHVKLRDVVIGMGACTD 113 Query: 162 CFKAEFEQIVLGKRVIRKTDLNKKLVQELLLCSAELSEFTTVVGNTMCTLDFYEGQGRLD 221 I D+ + V +A+ VGN FY G + Sbjct: 114 SKVNRIRFKDHDFAAIADFDMVRNAVD-----AAKALGIDARVGNLFSADLFYSPDGEMF 168 Query: 222 GALCSYTEKDKQAYLEAAYAAGVRNIEMESSVFAAMCSACGLQAAVVCVTLLNRLEGDQI 281 + Y G+ +EME++ + + G +A +C T+ + + + Sbjct: 169 DVMEKY---------------GILGVEMEAAGIYGVAAEFGAKALTIC-TVSDHIRTHEQ 212 Query: 282 SSPRNVLSEY 291 ++ + + Sbjct: 213 TTAAERQTTF 222 >3OCC-A nrPDB Length = 239 Score = 125 bits (314), Expect = 2e-29, Method: Composition-based stats. Identities = 48/250 (19%), Positives = 85/250 (34%), Gaps = 34/250 (13%) Query: 44 HNFPALFGDVKFVCVGGSPSRMKAFIRCVGAELGLDCPGRDYPNICAGTDRYAMYKVGPV 103 H + V + G P R K ++ R+ N+ YK + Sbjct: 5 HINAEMGDFADVVLMPGDPLRAKFIAETFLQDV------REVNNVRGMLGFTGTYKGRKI 58 Query: 104 LSVSHGMGIPSISIMLHELIKLLYYARCSNVTIIRIGTSGGI--GLEPGTVVITEQAVDT 161 + HGMGIPS SI ELI IIR+G+ G + ++ VVI A Sbjct: 59 SVMGHGMGIPSCSIYAKELI-----TDFGVKKIIRVGSCGAVRTDVKLRDVVIGMGACTD 113 Query: 162 CFKAEFEQIVLGKRVIRKTDLNKKLVQELLLCSAELSEFTTVVGNTMCTLDFYEGQGRLD 221 I ++ + V +A+ VGN FY ++ Sbjct: 114 SKVNRMRFKDHDYAAIADFEMTRNAVD-----AAKAKGVNVRVGNLFSADLFYTPDPQMF 168 Query: 222 GALCSYTEKDKQAYLEAAYAAGVRNIEMESSVFAAMCSACGLQAAVVCVTLLNRLEGDQI 281 + Y G+ +EME++ + + G +A +C T+ + + + Sbjct: 169 DVMEKY---------------GILGVEMEAAGIYGVAAEFGAKALTIC-TVSDHIRTGEQ 212 Query: 282 SSPRNVLSEY 291 ++ + + Sbjct: 213 TTAAERQTTF 222 >3TL6-A nrPDB Length = 242 Score = 124 bits (312), Expect = 3e-29, Method: Composition-based stats. Identities = 61/261 (23%), Positives = 98/261 (37%), Gaps = 52/261 (19%) Query: 44 HNFPALFGDVKFVCVGGSPSRMKAFIRCVGAELGLDCPGRDYPNICAGTDRYAMYKVGPV 103 HN + V + G P R+K ++ N G Y Y G Sbjct: 13 HNGAKYGEIAETVLMAGDPLRVKLLADTYLTDVVQY-------NSVRGAVGYTGYYKGVK 65 Query: 104 L-SVSHGMGIPSISIMLHELIKLLYYARCSNVTIIRIGTSGGI--GLEPGTVVITEQAVD 160 L +HGMG+PSI I +EL R IIRIG++G L+ G +VI + Sbjct: 66 LSVQAHGMGMPSIGIYAYELFNFYGVKR-----IIRIGSAGAFDESLKLGDIVI---GMG 117 Query: 161 TCFKAEFEQIVLGKRVIRKTDLNKKL--VQELLLC-----SAELSEFTTVVGNTMCTLDF 213 C+ + FE R+ D+ K + + LC +AE + VGN F Sbjct: 118 ACYDSNFE---------RQYDIPGKYSCIADFQLCREAVDAAEKLGYRYKVGNIYSANYF 168 Query: 214 YEGQGRLDGALCSYTEKDKQAYLEAAYAAGVRNIEMESSVFAAMCSACGLQAAVVCVTLL 273 Y+ + A GV +EME++ M +A + A+ +T+ Sbjct: 169 YDD----------------GDHSGAWKKMGVLAVEMEAAALY-MIAARARKQALCMLTIS 211 Query: 274 NRLEG-DQISSPRNVLSEYQQ 293 + G + + +++ Q Sbjct: 212 DLCYGSGEKMTAEERRTKFTQ 232 >3QPB-A nrPDB Length = 282 Score = 124 bits (310), Expect = 5e-29, Method: Composition-based stats. Identities = 56/228 (24%), Positives = 84/228 (36%), Gaps = 26/228 (11%) Query: 51 GDV-KFVCVGGSPSRMKAFIRCVGAELGLDCPGRDYPNICAGTDRYAMYKVGPVLSVSHG 109 GDV ++V + G P R + + D T V S G Sbjct: 42 GDVGRYVIMPGDPKRCAKIAEHFDNAVLVA----DSREYVTYT---GTLNGEKVSVTSTG 94 Query: 110 MGIPSISIMLHELIKLLYYARCSNVTIIRIGTSGGIGLEP--GTVVITEQAVDTCFKAEF 167 +G PS SI + EL C T IR+GT GGI L+ G +VI A+ Sbjct: 95 IGGPSASIAMEEL------KLCGADTFIRVGTCGGIELDVKGGDIVIATGAIRM-EGTSK 147 Query: 168 EQIVLGKRVIRKTDLNKKLVQELLLCSAELSEFTTVVGNTMCTLDFYEGQGRLDGALCSY 227 E + + ++ LV +A+ +T+ G C FY GQ + SY Sbjct: 148 EYAPIEFPAVADLEVTNALVN-----AAKKLGYTSHAGVVQCKDAFY-GQHEPERMPVSY 201 Query: 228 TEKDKQAYLEAAYAAGVRNIEMESSVFAAMCSACGLQAAVVCVTLLNR 275 + EA G + EMES+ S G++ + + N+ Sbjct: 202 ---ELLNKWEAWKRLGTKASEMESAALFVAASHLGVRCGSDFLVVGNQ 246 >4DAO-A nrPDB Length = 253 Score = 120 bits (301), Expect = 6e-28, Method: Composition-based stats. Identities = 46/252 (18%), Positives = 86/252 (34%), Gaps = 35/252 (13%) Query: 42 SRHNFPALFGDVKFVCVGGSPSRMKAFIRCVGAELGLDCPGRDYPNICAGTDRYAMYKVG 101 S H V + G P R K E L+ Y + YK Sbjct: 22 SVHIGAEKGQIADTVLLPGDPLRAKFIA-----ETYLENVEC-YNEVRGMYGFTGTYKGK 75 Query: 102 PVLSVSHGMGIPSISIMLHELIKLLYYARCSNVTIIRIGTSGGI--GLEPGTVVITEQAV 159 + GMG+PSISI ++ELI+ +IR+G+ G I ++ V++ + Sbjct: 76 KISVQGTGMGVPSISIYVNELIQ-----SYDVQNLIRVGSCGAIRKDVKVRDVILAMTSS 130 Query: 160 DTCFKAEFEQIVLGKRVIRKTDLNKKLVQELLLCSAELSEFTTVVGNTMCTLDFYEGQGR 219 + +L K +A+ VG+ FY Sbjct: 131 TDSQMNRVAFGSVDFAPCADFELLKNAYD-----AAKDKGVPVTVGSVFTADQFYNDD-- 183 Query: 220 LDGALCSYTEKDKQAYLEAAYAAGVRNIEMESSVFAAMCSACGLQAAVVCVTLLNRLEGD 279 ++ +K A GV +EME++ + + G +A + +T+ + + Sbjct: 184 --------SQIEKLA------KYGVLGVEMETTALYTLAAKHGRKALSI-LTVSDHVLTG 228 Query: 280 QISSPRNVLSEY 291 + ++ + + Sbjct: 229 EETTAEERQTTF 240 >4M7W-A nrPDB Length = 258 Score = 119 bits (298), Expect = 1e-27, Method: Composition-based stats. Identities = 46/243 (18%), Positives = 79/243 (32%), Gaps = 34/243 (13%) Query: 53 VKFVCVGGSPSRMKAFIRCVGAELGLDCPGRDYPNICAGTDRYAMYKVGPVLSVSHGMGI 112 + + + G P R K ++ Y N+ YK V GMG+ Sbjct: 36 AETILLPGDPLRAKYIAETFLEDV------VQYNNVRGMLGFTGTYKGKKVSVQGTGMGV 89 Query: 113 PSISIMLHELIKLLYYARCSNVTIIRIGTSGGIG--LEPGTVVITEQAVDTCFKAEFEQI 170 PSI I HELI +IR+GT+G ++ VVI A + Sbjct: 90 PSIGIYSHELI-----TEFGVKNLIRVGTAGSYQEDVKVRDVVIAMSASTDSAINKLRFN 144 Query: 171 VLGKRVIRKTDLNKKLVQELLLCSAELSEFTTVVGNTMCTLDFYEGQGRLDGALCSYTEK 230 +DL K + A+ GN + FY Sbjct: 145 GADYAPTASSDLVFKAYE-----IAKAKGLNVKAGNVFTSDTFYGDDPN----------- 188 Query: 231 DKQAYLEAAYAAGVRNIEMESSVFAAMCSACGLQAAVVCVTLLNRLEGDQISSPRNVLSE 290 + GV +EME++ + G+ A + +T+ + +++S + Sbjct: 189 ----AWKKWAEFGVLCVEMETAQLYTTAAKLGVNALTL-LTISDSFITHEVTSAEERQTT 243 Query: 291 YQQ 293 + + Sbjct: 244 FNE 246 >1VHW-A nrPDB Length = 253 Score = 115 bits (288), Expect = 2e-26, Method: Composition-based stats. Identities = 55/263 (20%), Positives = 99/263 (37%), Gaps = 45/263 (17%) Query: 39 LTTSRHNFPALFGD-VKFVCVGGSPSRMKAFIRCVGAELGLDCPGRDYPNICAGTDRYAM 97 ++ + + A GD V + G P R K C D N+ T Sbjct: 1 MSLATPHINAQMGDFADVVLMPGDPLRAKYIAENFLDNAVQVC---DVRNMFGYT---GT 54 Query: 98 YKVGPVLSVSHGMGIPSISIMLHELIKLLYYARCSNVTIIRIGTSGGI--GLEPGTVVIT 155 YK + + HGMGIPS SI + ELIK IIR+G+ G + G++ VVI Sbjct: 55 YKGRRISVMGHGMGIPSCSIYVTELIK-----DYGVKKIIRVGSCGAVNEGIKVRDVVI- 108 Query: 156 EQAVDTCFKAEFEQIVLGKRVIRKTDLNKKLVQELLL-----CSAELSEFTTVVGNTMCT 210 + C ++ +I R D + + + + +A+ VGN Sbjct: 109 --GMGACTDSKVNRI-------RFKDHDFAAIADYKMVKAAEEAAKARGIDVKVGNLFSA 159 Query: 211 LDFYEGQGRLDGALCSYTEKDKQAYLEAAYAAGVRNIEMESSVFAAMCSACGLQAAVVCV 270 FY + + Y G+ +EME++ + + G +A +C Sbjct: 160 ELFYTPDPSMFDVMDKY---------------GIVGVEMEAAGIYGVAAEYGAKALAIC- 203 Query: 271 TLLNRLEGDQISSPRNVLSEYQQ 293 T+ + ++ + ++ + + + Sbjct: 204 TVSDHIKTGEQTTSEERQNTFNE 226 >6F5I-A nrPDB Length = 233 Score = 110 bits (274), Expect = 9e-25, Method: Composition-based stats. Identities = 48/248 (19%), Positives = 84/248 (33%), Gaps = 35/248 (14%) Query: 48 ALFGDVKFVCV-GGSPSRMKAFIRCVGAELGLDCPGRDYPNICAGTDRYAMYKVGPVLSV 106 A GD C+ G P R+ + + ++ N+ YK + + Sbjct: 7 AKIGDFYPQCLLCGDPLRVSYIAKKFLQDA------KEITNVRNMLGFSGKYKGRGISLM 60 Query: 107 SHGMGIPSISIMLHELIKLLYYARCSNVTIIRIGTSGGIGLEPG--TVVITEQAVDTCFK 164 HGMGI S +I + ELIK ++RIGT G I + G +++ A Sbjct: 61 GHGMGIASCTIYVTELIK-----TYQVKELLRIGTCGAISPKVGLKDIIMATGASTDSKT 115 Query: 165 AEFEQIVLGKRVIRKTDLNKKLVQELLLCSAELSEFTTVVGNTMCTLDFYEGQGRLDGAL 224 + +L+ + Q A+ VGN + FY + + Sbjct: 116 NRVRFLNHDLSATPDFELSLRAYQT-----AKRLGIDLKVGNVFSSDFFYSFETHAFDLM 170 Query: 225 CSYTEKDKQAYLEAAYAAGVRNIEMESSVFAAMCSACGLQAAVVCVTLLNRLEGDQISSP 284 Y IEME++ A +A +C ++ + L + SP Sbjct: 171 AKYNH---------------LAIEMEAAGLYATAMELNAKALCLC-SVSDHLITKEALSP 214 Query: 285 RNVLSEYQ 292 + + + Sbjct: 215 KERVESFD 222 >4LDN-A nrPDB Length = 261 Score = 109 bits (271), Expect = 2e-24, Method: Composition-based stats. Identities = 50/266 (18%), Positives = 93/266 (34%), Gaps = 39/266 (14%) Query: 29 MKEDILYHFNLTTSRHNFP-ALFGDVKFVCVGGSPSRMKAFIRCVGAELGLDCPGRDYPN 87 + + LY +++T N P F D + G P R K E L+ + Sbjct: 13 LGTENLYFQSMSTPHINAPLDAFADTILM--PGDPLRAKLIA-----ETYLEN-VVQVTD 64 Query: 88 ICAGTDRYAMYKVGPVLSVSHGMGIPSISIMLHELIKLLYYARCSNVTIIRIGTSGGIG- 146 + +K + + HGMG PS SI HEL+ IRIG+ G I Sbjct: 65 VRGMLGFTGEFKGRKISVMGHGMGAPSASIYFHELM-----TTYKVKNFIRIGSCGAIHD 119 Query: 147 -LEPGTVVITEQAVDTCFKAEFEQIVLGKRVIRKTDLNKKLVQELLLCSAELSEFTTVVG 205 ++ +++ A ++ + V L + ++ +VG Sbjct: 120 DVKLKDLIVAIGASTDSKMNRIRFKDNDFAATANYNMLSECVNTL-----KTTDINYLVG 174 Query: 206 NTMCTLDFY-EGQGRLDGALCSYTEKDKQAYLEAAYAAGVRNIEMESSVFAAMCSACGLQ 264 N + FY + + D + A Y G+ +EME + + + Sbjct: 175 NVFSSDLFYRPDEEQYD--------------MMARY--GILGVEMEVNALYSAAAENHCN 218 Query: 265 AAVVCVTLLNRLEGDQISSPRNVLSE 290 A +C T+ + ++ + + +E Sbjct: 219 AVALC-TVTDHIKNHEHLTADERRTE 243 >1JE0-A nrPDB Length = 236 Score = 109 bits (271), Expect = 2e-24, Method: Composition-based stats. Identities = 50/242 (20%), Positives = 74/242 (30%), Gaps = 39/242 (16%) Query: 53 VKFVCVGGSPSRMKAFIRCVGAELGLDCPGRDYPNICAGTDRYAMYKVGPVLSVSHGMGI 112 + V V G P R + L P N Y V +HG+G Sbjct: 14 AERVLVVGDPGRARLLS------TLLQNPKLTNEN-RGFLVYTGKYNGETVSIATHGIGG 66 Query: 113 PSISIMLHELIKLLYYARCSNVTIIRIGTSGG--IGLEPGTVVITEQAVDTCFKAEFEQI 170 PSI+I+L EL L IR GT+G + G +I A F Q Sbjct: 67 PSIAIVLEELAML------GANVFIRYGTTGALVPYINLGEYIIVTGA-SYNQGGLFYQY 119 Query: 171 VLGK---RVIRKTDLNKKLVQELLLCSAELSEFTTVVGNTMCTLDFYEGQGRLDGALCSY 227 + +L KLV VGN + FY Sbjct: 120 LRDNACVASTPDFELTNKLVTSFSKR-----NLKYYVGNVFSSDAFYAEDEE-------- 166 Query: 228 TEKDKQAYLEAAYAAGVRNIEMESSVFAAMCSACGLQAAVVCVTLLNRLEGDQISSPRNV 287 +++ + G +EME + + G ++A V V N +G + + Sbjct: 167 -------FVKKWSSRGNIAVEMECATLFTLSKVKGWKSATVLVVSDNLAKGGIWITKEEL 219 Query: 288 LS 289 Sbjct: 220 EK 221 >4TYM-A nrPDB Length = 258 Score = 108 bits (270), Expect = 2e-24, Method: Composition-based stats. Identities = 51/238 (21%), Positives = 82/238 (34%), Gaps = 34/238 (14%) Query: 56 VCVGGSPSRMKAFIRCVGAELGLDCPGRDYPNICAGTDRYAMYKVGPVLSVSHGMGIPSI 115 + + G P R K + N+ T YK V + GMG+PSI Sbjct: 38 ILLPGDPLRAKFIAENFLEDAVCFNT---VRNMFGYT---GTYKGHRVSVMGTGMGMPSI 91 Query: 116 SIMLHELIKLLYYARCSNVTIIRIGTSGGI--GLEPGTVVITEQAVDTCFKAEFEQIVLG 173 SI ELI T+IR+GT+G I + +V+ + A + Sbjct: 92 SIYARELI-----VDYGVKTLIRVGTAGAINPDIHVRELVLAQAAATNSNIIRNDWPEFD 146 Query: 174 KRVIRKTDLNKKLVQELLLCSAELSEFTTVVGNTMCTLDFYEGQGRLDGALCSYTEKDKQ 233 I L K A+ + TT VG+ + + FY Q + AL Sbjct: 147 FPQIADFKLLDKAYH-----IAKEMDITTHVGSVLSSDVFYSNQPDRNMALGK------- 194 Query: 234 AYLEAAYAAGVRNIEMESSVFAAMCSACGLQAAVVCVTLLNRLEGDQISSPRNVLSEY 291 GV IEME++ + + + A + +T+ + L + + Sbjct: 195 --------LGVHAIEMEAAALYYLAAQHNVNA-LAMMTISDNLNNPEEDTSAEERQTT 243 >4LNH-A nrPDB Length = 266 Score = 104 bits (259), Expect = 5e-23, Method: Composition-based stats. Identities = 49/242 (20%), Positives = 83/242 (34%), Gaps = 35/242 (14%) Query: 29 MKEDILYHFNLTTSRHNFPALFGDVKFVCVGGSPSRMKAFIRCVGAELGLDCPGRDYPNI 88 + + LY +++ H +V V G P R+ + + + L R+Y Sbjct: 13 LGTENLYFQSMSKQPHICVDENQVSPYVIVCGEPDRVNRIVELMDN-VELLAENREYRVF 71 Query: 89 CAGTDRYAMYKVGPVLSVSHGMGIPSISIMLHELIKLLYYARCSNVTIIRIGTSGGI--G 146 +YK + S G+G PS+ I + EL C +IR+G++G + Sbjct: 72 ------NGVYKGTTITICSTGIGAPSMIIAVEEL------KLCGATHVIRVGSAGAMQDH 119 Query: 147 LEPGTVVITEQAVDTCFKAEFEQIVLGKRVIRKTDLNKKLVQELLLCSAELSEFTTVVGN 206 ++ G +++ E AV I L K++ L E G Sbjct: 120 IQLGELIVAEGAVRD-EGGSKAYISSAYPAYASFALLKEISHFL-----ENQSVKYYFGV 173 Query: 207 TMCTLDFYEGQGRLDGALCSYTEKDKQAYLEAAYAAGVRNIEMESSVFAAMCSACGLQAA 266 FY + LC Y G+ +ME+S + GLQ A Sbjct: 174 VRSHDSFYTDEE---DQLCQY-----------WNKKGILGADMETSALFTVGRLRGLQVA 219 Query: 267 VV 268 + Sbjct: 220 SI 221 >4LKR-A nrPDB Length = 256 Score = 96.1 bits (237), Expect = 2e-20, Method: Composition-based stats. Identities = 48/265 (18%), Positives = 89/265 (33%), Gaps = 36/265 (13%) Query: 29 MKEDILYHFNLTTSRHNFPALFGDVKFVCVGGSPSRMKAFIRCVGAELGLDCPGRDYPNI 88 + + LY ++T + P F + V + G P R K + + N+ Sbjct: 13 LGTENLYFQSMTAHINAQPTDFAET--VIMPGDPLRAKYIAETYLTDA------VEVTNV 64 Query: 89 CAGTDRYAMYKVGPVLSVSHGMGIPSISIMLHELIKLLYYARCSNVTIIRIGTSGGI--G 146 Y+ + + HGMGI S+ + HELI R IIRIG+ G Sbjct: 65 RNMLGYTGYYQGQRISVMGHGMGISSMVLYGHELINFFGVKR-----IIRIGSLGATQQH 119 Query: 147 LEPGTVVITEQAVDTCFKAEFEQIVLGKRVIRKTDLNKKLVQELLLCSAELSEFTTVVGN 206 +E V++ + A L K + A + VGN Sbjct: 120 VEMRDVILAQAAGTDSPTNAKRSSGYHMATSATFSLLHKAYTK-----ANEKGISVKVGN 174 Query: 207 TMCTLDFYEGQGRLDGALCSYTEKDKQAYLEAAYAAGVRNIEMESSVFAAMCSACGLQAA 266 +Y+ + AL + GV I+ME + + G+++ Sbjct: 175 VFSGDLYYDPDEDMIPALERF---------------GVLGIDMEVAGLYGLAHQQGIESL 219 Query: 267 VVCVTLLNRLEGDQISSPRNVLSEY 291 + +T+ + + ++ + + Sbjct: 220 AI-LTVSDHCLTGEETTAQERQLSF 243 >3MB8-A nrPDB Length = 279 Score = 86.5 bits (212), Expect = 1e-17, Method: Composition-based stats. Identities = 48/229 (20%), Positives = 79/229 (34%), Gaps = 36/229 (15%) Query: 55 FVCVGGSPSRMKAFIRCVGAELGLDCPGRDYPNICAGTDRYAMYKVGPVLSVSHGMGIPS 114 V + G P+R + + L R+Y + +Y P+ +SHG+G P Sbjct: 23 VVIIVGDPARTEEVANMCEKKQELAY-NREYRSFR------VVYDSQPITVISHGIGCPG 75 Query: 115 ISIMLHELIKLLYYARCSNVTIIRIGTSGGI---GLEPGTVVITEQAVDTCFKAEFEQIV 171 SI + EL L IIR GT G + L+ G V +T AV+ + Sbjct: 76 TSIAIEELAYLG------AKVIIRAGTCGSLKPKTLKQGDVCVTYAAVNE-TGLISNILP 128 Query: 172 LGKRVIRKTDLNKKLVQELLLCSAELSEFTTVVGNTMCTLDFYEGQGRLDGALCSYTEKD 231 G + V + L+ +A+ G + FY+ Sbjct: 129 EGFPCVA-----TPHVYQALMDAAKELGIEAASGIGVTQDYFYQN--------------G 169 Query: 232 KQAYLEAAYAAGVRNIEMESSVFAAMCSACGLQAAVVCVTLLNRLEGDQ 280 Y+ I+ME S +C A G+ + + L+ D+ Sbjct: 170 ILPSKLEMYSKCCDVIDMEMSGVLGLCQARGIATCGILAVDGSPLQWDE 218 >3EMV-A nrPDB Length = 253 Score = 82.2 bits (201), Expect = 3e-16, Method: Composition-based stats. Identities = 53/286 (18%), Positives = 91/286 (31%), Gaps = 47/286 (16%) Query: 29 MKEDILYHFNLTTSRHNFPALFGDVKFVCVGGSPSRMKAFIRCVGAELGLDCPGRDYPNI 88 M+ ++ H LT + V V G P R+ + + L R+Y ++ Sbjct: 1 MEGEMQRHIKLTKA--------QTTPVVLVVGDPGRVDKVKVLCDSYVDLAY-NREYKSV 51 Query: 89 CAGTDRYAMYKVGPVLSVSHGMGIPSISIMLHELIKLLYYARCSNVTIIRIGTSGGI--- 145 YK L VSHG+G +I EL+ IIR G+ G + Sbjct: 52 ------ECTYKGQKFLCVSHGVGSAGCAICFEELMN------NGAKVIIRAGSCGSLQPT 99 Query: 146 GLEPGTVVITEQAVDTCFKAEFEQIVLGKRVIRKTDLNKKLVQELLLCSAELSEFTTVVG 205 ++ G + I AV + I + ++ L AE + G Sbjct: 100 QMKRGDICICNAAVREDRVSHL-MIYSDFPAVADYEVYAT-----LNQVAEELKVPVFNG 153 Query: 206 NTMCTLDFYEGQGRLDGALCSYTEKDKQAYLEAAYAAGVRNIEMESSVFAAMCSACGLQA 265 ++ + +Y K LE A V +EME + M + ++ Sbjct: 154 ISLSSDMYYP-------------HKIIPTRLEDYSKANVAVVEMEVATLMVMGTLRKVKT 200 Query: 266 AVVCVTLLNRLEGDQISSP----RNVLSEYQQRPQRLVSYFIKKKL 307 + + L+ D+ L + + KK L Sbjct: 201 GGIFIVDGCPLKWDEGDFDNNLVPERLENMIKISLETCARLAKKYL 246 >5ZNI-A nrPDB Length = 245 Score = 74.5 bits (181), Expect = 6e-14, Method: Composition-based stats. Identities = 42/244 (17%), Positives = 81/244 (33%), Gaps = 43/244 (17%) Query: 31 EDILYHFNLTTSRHNFPALFGDVKFVCVGGSPSRMKAFIRCVGAELGLDCPGRDYPNICA 90 +++L H ++ + V V G P R+ + + L R+Y ++ Sbjct: 2 DNLLRHLKISKEQI--------TPVVLVVGDPGRVDKIKVVCDSYVDLAY-NREYKSV-- 50 Query: 91 GTDRYAMYKVGPVLSVSHGMGIPSISIMLHELIKLLYYARCSNVTIIRIGTSGGIG---L 147 YK L VSHG+G ++ EL + IIR G+ G + + Sbjct: 51 ----ECHYKGQKFLCVSHGVGSAGCAVCFEELCQ------NGAKVIIRAGSCGSLQPDLI 100 Query: 148 EPGTVVITEQAVDTCFKAEFEQIVLGKRVIRKTDLNKKLVQELLLCSAELSEFTTVVGNT 207 + G + I AV + I + D+ + L A+ G + Sbjct: 101 KRGDICICNAAVREDRVSHL-LIHGDFPAVGDFDVY-----DTLNKCAQELNVPVFNGIS 154 Query: 208 MCTLDFYEGQGRLDGALCSYTEKDKQAYLEAAYAAGVRNIEMESSVFAAMCSACGLQAAV 267 + + +Y K + LE A +EME + + + ++ Sbjct: 155 VSSDMYYPN-------------KIIPSRLEDYSKANAAVVEMELATLMVIGTLRKVKTGG 201 Query: 268 VCVT 271 + + Sbjct: 202 ILIV 205 >1NW4-A nrPDB Length = 276 Score = 74.5 bits (181), Expect = 6e-14, Method: Composition-based stats. Identities = 42/244 (17%), Positives = 81/244 (33%), Gaps = 43/244 (17%) Query: 31 EDILYHFNLTTSRHNFPALFGDVKFVCVGGSPSRMKAFIRCVGAELGLDCPGRDYPNICA 90 +++L H ++ + V V G P R+ + + L R+Y ++ Sbjct: 4 DNLLRHLKISKEQI--------TPVVLVVGDPGRVDKIKVVCDSYVDLAY-NREYKSV-- 52 Query: 91 GTDRYAMYKVGPVLSVSHGMGIPSISIMLHELIKLLYYARCSNVTIIRIGTSGGIG---L 147 YK L VSHG+G ++ EL + IIR G+ G + + Sbjct: 53 ----ECHYKGQKFLCVSHGVGSAGCAVCFEELCQ------NGAKVIIRAGSCGSLQPDLI 102 Query: 148 EPGTVVITEQAVDTCFKAEFEQIVLGKRVIRKTDLNKKLVQELLLCSAELSEFTTVVGNT 207 + G + I AV + I + D+ + L A+ G + Sbjct: 103 KRGDICICNAAVREDRVSHL-LIHGDFPAVGDFDVY-----DTLNKCAQELNVPVFNGIS 156 Query: 208 MCTLDFYEGQGRLDGALCSYTEKDKQAYLEAAYAAGVRNIEMESSVFAAMCSACGLQAAV 267 + + +Y K + LE A +EME + + + ++ Sbjct: 157 VSSDMYYPN-------------KIIPSRLEDYSKANAAVVEMELATLMVIGTLRKVKTGG 203 Query: 268 VCVT 271 + + Sbjct: 204 ILIV 207 >6IF8-A nrPDB Length = 260 Score = 48.7 bits (114), Expect = 3e-06, Method: Composition-based stats. Identities = 46/257 (17%), Positives = 82/257 (31%), Gaps = 32/257 (12%) Query: 61 SPSRMK-AFIRCVGAELGLDCPGRDYPNIC--AGTDRY-AMYKVGPVLSVSHGMGIPSIS 116 P MK I + E+ L P G + Y V+ G+G + S Sbjct: 27 DPEFMKVGIIGAMEQEVALLRSQMSNPTTLQLGGCEFYQGTLAGKEVILTRSGIGKVAAS 86 Query: 117 IMLHELIKLLYYARCSNVTIIRIGTSGGIG--LEPGTVVITEQAVDTCFKAEFEQIVLGK 174 + L++ + C +I G++GG L G VVI + +G+ Sbjct: 87 VATSLLLE-KFAPDC----VINTGSAGGFAQDLHIGDVVIASEMRFHDVDVTAFGYEMGQ 141 Query: 175 RVI--RKTDLNKKLVQELLLCSAELSEFTTVVGNTMCTLDFYEGQGRLDGALCSYTEKDK 232 ++ L+ C AE + T VG F + D Sbjct: 142 MAQQPAAFPCDETLIAVAQDCIAEQGKHQTKVGLICTGDQF-------------MCKPDA 188 Query: 233 QAYLEAAYAAGVRNIEMESSVFAAMCSACGLQAAVVCVTLLNRLEGDQISSPRNVLSEYQ 292 A A + + +EME + +C + +V + + +Q+ + Sbjct: 189 IAKARADFPQ-MLAVEMEGAAIGQVCHMFKV-PYLVVRAMSDIAGKEQV----ESFDAFI 242 Query: 293 QRPQRLVSYFIKKKLSK 309 + + + I K L K Sbjct: 243 EVAGKHSAEVIIKMLGK 259 >4G41-A nrPDB Length = 236 Score = 46.4 bits (108), Expect = 2e-05, Method: Composition-based stats. Identities = 30/179 (16%), Positives = 60/179 (33%), Gaps = 20/179 (11%) Query: 130 RCSNVTIIRIGTSGGI--GLEPGTVVITEQAVDTCFKAEFEQIVLGKRVIR--KTDLNKK 185 II G++G + L G VV+ ++ V A G+ + D + + Sbjct: 70 HFKAQAIINTGSAGAVASHLAIGDVVVADRLVYHDVDATAFGYAYGQMAGQPLYYDCDPQ 129 Query: 186 LVQELLLCSAELSEFTTVVGNTMCTLDFYEGQGRLDGALCSYTEKDKQAYLEAAYAAGVR 245 V + VG F GQ ++D +++ V Sbjct: 130 FVAIFKQVLKHE-KTNGQVGLIATGDSFVAGQDKIDQIKTAFS--------------NVL 174 Query: 246 NIEMESSVFAAMCSACGLQAAVVCVTLLNRLEGDQISSPRNVLSEYQQRPQRLVSYFIK 304 +EME + A G + +V + + D + + E +R +++ F++ Sbjct: 175 AVEMEGAAIAQAAHTAG-KPFIVVRAMSDTAAHDANITFDQFIIEAGKRSAQILMTFLE 232 >4WKO-A nrPDB Length = 245 Score = 45.3 bits (105), Expect = 3e-05, Method: Composition-based stats. Identities = 34/238 (14%), Positives = 73/238 (30%), Gaps = 32/238 (13%) Query: 78 LDCPGRDYPNICAGTDRY--AMYKVGPVLSVSHGMG-IPSISIMLHELIKLLYYARCSNV 134 L+ G D+ I G + + +Y ++ +G + S ++ Sbjct: 33 LELFGVDFEEIPLGGNVFHKGVYHNKEIIVAYSKIGKVHSTLTTTSMILAFG------VQ 86 Query: 135 TIIRIGTSGGI--GLEPGTVVITEQAVDTCFKAEFEQIVLGKRVIRKTDLNKK-LVQELL 191 ++ G +G + L+ +++ Q V LG + + L Sbjct: 87 KVLFSGVAGSLVKDLKINDLLVATQLVQHDVDLSAFDHPLGFIPESAIFIETSGSLNALA 146 Query: 192 LCSAELSEFTTVVGNTMCTLDFYEGQGRLDGALCSYTEKDKQAYLEAAYAAGVRNIEMES 251 A G F + R + + + +A +EME Sbjct: 147 KKIANEQHIALKEGVIASGDQFVHSKERKE-----FLVSEFKAS----------AVEMEG 191 Query: 252 SVFAAMCSACGLQAAVVCVTLLNRLEGDQISSPRNVLSEYQQRPQRLVSYFIKKKLSK 309 + A +C G+ V+ N E +S E+ ++ + F+K + + Sbjct: 192 ASVAFVCQKFGVPCCVLRSISDNADEKAGMS-----FDEFLEKSAHTSAKFLKSMVDE 244 >1ZOS-A nrPDB Length = 230 Score = 44.9 bits (104), Expect = 4e-05, Method: Composition-based stats. Identities = 37/244 (15%), Positives = 76/244 (31%), Gaps = 28/244 (11%) Query: 68 FIRCVGAELGLDCPGRDYPN---ICAGTDRYAMYKVGPVLSVSHGMGIPSISIMLHELIK 124 I + EL D + T V+ V G+G ++ + L Sbjct: 5 IIAAMPEELAYLVQHLDNTQEQVVLGNTYHTGTIASHEVVLVESGIGKVMSAMSVAILA- 63 Query: 125 LLYYARCSNVTIIRIGTSGGI--GLEPGTVVITEQAVDTCFKAEFEQIVLGKRVIR--KT 180 +I G++G + G+ G VVI ++ G+ + Sbjct: 64 ----DHFQVDALINTGSAGAVAEGIAVGDVVIADKLAYHDVDVTAFGYAYGQMAQQPLYF 119 Query: 181 DLNKKLVQELLLCSAELSEFTTVVGNTMCTLDFYEGQGRLDGALCSYTEKDKQAYLEAAY 240 + +K V ++ ++L +G F G +++ + E Sbjct: 120 ESDKTFVAQIQESLSQLD-QNWHLGLIATGDSFVAGNDKIEAIKSHFPE----------- 167 Query: 241 AAGVRNIEMESSVFAAMCSACGLQAAVVCVTLLNRLEGDQISSPRNVLSEYQQRPQRLVS 300 V +EME + A L +V + + + + E +R +++ Sbjct: 168 ---VLAVEMEGAAIAQAAHTLNL-PVLVIRAMSDNANHEANIFFDEFIIEAGRRSAQVLL 223 Query: 301 YFIK 304 F+K Sbjct: 224 AFLK 227 >4KN5-A nrPDB Length = 253 Score = 44.9 bits (104), Expect = 5e-05, Method: Composition-based stats. Identities = 34/204 (16%), Positives = 69/204 (33%), Gaps = 24/204 (11%) Query: 103 VLSVSHGMGIPSISIMLHELIKLLYYARCSNVTIIRIGTSGGIG--LEPGTVVITEQAVD 160 V+ V G+G + L L +I G++G +G L G +VI + Sbjct: 65 VVVVESGIGK-----VASALTTTLLITNFGVDAVINSGSAGALGTDLRIGDIVIADYLAY 119 Query: 161 TCFKAEFEQIVLGKRVI--RKTDLNKKLVQELLLCSAELSEFTTVVGNTMCTLDFYEGQG 218 A G+ + + L +L ++++ V G + + F Sbjct: 120 ADADARAFGYAYGQVPQQPARFKADTDLSNDLSESYEKVTDARLVRGLVVTSDSFIASNE 179 Query: 219 RLDGALCSYTEKDKQAYLEAAYAAGVRNIEMESSVFAAMCSACGLQAAVVCVTLLNRLEG 278 + L + E EME + A + + + AVV + + G Sbjct: 180 QKQTILTHFPEAQSA--------------EMEGASIAQVANYFDVPFAVV-RAISDNANG 224 Query: 279 DQISSPRNVLSEYQQRPQRLVSYF 302 + + + + E Q+ +++ F Sbjct: 225 EAGMTFDDFIVEAGQQSAQVLINF 248 >4WKB-A nrPDB Length = 244 Score = 41.4 bits (95), Expect = 5e-04, Method: Composition-based stats. Identities = 40/228 (17%), Positives = 73/228 (32%), Gaps = 27/228 (11%) Query: 87 NICAGTDRYAMYKVGPVLSVSHGMGIPSISIMLHELIKLLYYARCSNVTIIRIGTSGGI- 145 N T + V+ + G+G S + L L ++ + +I G++GG Sbjct: 27 NQAGCTFYSGQIQGVDVVLLQSGIGKVSAA-----LGTALLISQYAPDVVINTGSAGGFD 81 Query: 146 -GLEPGTVVITEQAVDTCFKAEFEQIVLGKRV--IRKTDLNKKLVQELLLCSAELSEFTT 202 L G VVI+ + +G+ ++KL+ A+L Sbjct: 82 ASLNVGDVVISSEVRHHDADVTAFGYEIGQMAGQPAAFKADEKLMTVAEQALAQLPNTHA 141 Query: 203 VVGNTMCTLDFYEGQGRLDGALCSYTEKDKQAYLEAAYAAGVRNIEMESSVFAAMCSACG 262 V G F R + + + V +EME+S A C Sbjct: 142 VRGLICTGDAFVCTAERQ-----QFIRQHFPS---------VVAVEMEASAIAQTCHQFK 187 Query: 263 LQAAVVCVTLLNRLEGDQISSPRNVLSEYQQRPQRLV---SYFIKKKL 307 + VV + + + + S L + +V +K+ L Sbjct: 188 V-PFVVVRAISDVADKESPLSFEEFLPLAAKSSSAMVLKMVELLKENL 234 >5UE1-A nrPDB Length = 234 Score = 36.0 bits (81), Expect = 0.020, Method: Composition-based stats. Identities = 36/212 (16%), Positives = 67/212 (31%), Gaps = 24/212 (11%) Query: 96 AMYKVGPVLSVSHGMGIPSISIMLHELIKLLYYARCSNVTIIRIGTSGGI--GLEPGTVV 153 V+ + G+G + ++ LI A + ++ G++GG L G VV Sbjct: 39 GTLNGADVVLLQSGIGKVAAAVGTTLLI-----AEHNVDVVLNTGSAGGFDSSLNLGDVV 93 Query: 154 ITEQAVDTCFKAEFEQIVLGKRVI--RKTDLNKKLVQELLLCSAELSEFTTVVGNTMCTL 211 I+ + +G+ ++KL+ E+S+ V G Sbjct: 94 ISTEVRHHDADVTAFGYEMGQMAQQPAAFIADEKLITTAEQALTEMSDKHAVRGLICTGD 153 Query: 212 DFYEGQGRLDGALCSYTEKDKQAYLEAAYAAGVRNIEMESSVFAAMCSACGLQAAVVCVT 271 F R + + + V +EME+S A C VV Sbjct: 154 VFVCTPERQE-----FIRTHFPS---------VIAVEMEASAIAQTCHQFN-TPFVVVRA 198 Query: 272 LLNRLEGDQISSPRNVLSEYQQRPQRLVSYFI 303 + + + + S L Q +V + Sbjct: 199 ISDVADKESPMSFDEFLPLAAQSSSEMVLNMV 230 >4YML-A nrPDB Length = 245 Score = 34.9 bits (78), Expect = 0.046, Method: Composition-based stats. Identities = 26/184 (14%), Positives = 54/184 (29%), Gaps = 19/184 (10%) Query: 130 RCSNVTIIRIGTSG--GIGLEPGTVVITEQAVDTCFKAEFEQIVLGK-RVIRKTDLNKKL 186 C II G++G L+ G +V++++A G+ Sbjct: 65 HCKPDVIINTGSAGGLAPTLKVGDIVVSDEARYHDADVTAFGYEYGQLPGCPAGFKADDK 124 Query: 187 VQELLLCSAELSEFTTVVGNTMCTLDFYEGQGRLDGALCSYTEKDKQAYLEAAYAAGVRN 246 + V G + F G A + + + Sbjct: 125 LIAAAEACIAELNLNAVRGLIVSGDAFING-------------SVGLAKIRHNFPQAI-A 170 Query: 247 IEMESSVFAAMCSACGLQAAVVCVTLLNRLEGDQISSPRNVLSEYQQRPQRLVSYFIKKK 306 +EME++ A +C + V V ++ + Q + + L+ + +K Sbjct: 171 VEMEATAIAHVCHNFNV--PFVVVRAISDVADQQSHLSFDEFLAVAAKQSSLMVESLVQK 228 Query: 307 LSKA 310 L+ Sbjct: 229 LAHG 232 >5DK6-A nrPDB Length = 265 Score = 34.5 bits (77), Expect = 0.067, Method: Composition-based stats. Identities = 37/233 (15%), Positives = 70/233 (30%), Gaps = 33/233 (14%) Query: 86 PNICAGTDRYAMYKVGPVLSVSHGMGIPSISIMLHELIKLLYYARCSNVTIIRIGTSGGI 145 T V+ V G+G + L + R ++ G++GG Sbjct: 48 TEHAGYTFHQGQLDGSDVVIVQSGIGK-----VAAALATAILIDRFQVDYVVNTGSAGGF 102 Query: 146 --GLEPGTVVITEQAVDTCFKAEFEQIVLGKRVI--RKTDLNKKLVQELLLCSAELS--- 198 L+ G +V++ + +G+ + LV +LS Sbjct: 103 DASLKVGDIVVSSEVRYHDVDLTAFGYEIGQLPANPAAFMPHDDLVAAAKKGIEQLSQTA 162 Query: 199 --EFTTVVGNTMCTLDFYEGQGRLDGALCSYTEKDKQAYLEAAYAAGVRNIEMESSVFAA 256 V G F T+++ A A + + +EME + A Sbjct: 163 GENIKAVTGLITTGDTF-------------MTKEEDVAKARANFPT-MAAVEMEGAAIAQ 208 Query: 257 MCSACGLQAAVVCVTLLNRLEGDQISSPRNVLSEYQQRPQRLVSYFIKKKLSK 309 C L+ V + L+ + G + + EY + S + L + Sbjct: 209 AC--LQLKTPFVVIRSLSDIAGKE---SPHTFEEYLETAAVNSSQLVLNMLGQ 256 >1TQY-B nrPDB Length = 415 Score = 34.1 bits (76), Expect = 0.080, Method: Composition-based stats. Identities = 35/168 (20%), Positives = 56/168 (33%), Gaps = 23/168 (13%) Query: 77 GLDCPGRDYPNICA-GTDRYAMYK--------VGPVLSVSHGMGIPSISIMLHELIKLLY 127 G D R++ + + G ++Y+ +S+ HGM PS +++ + L Sbjct: 116 GFDFTHREFRKLWSEGPKSVSVYESFAWFYAVNTGQISIRHGMRGPSSALVAEQAGGLDA 175 Query: 128 YARCSNVTIIRIGT----SGGI--GLEPGTVV--ITEQAVDTCFKAEFEQIVLGKRVIRK 179 IR GT SGG+ L+P V I + T + + +R Sbjct: 176 LGH--ARRTIRRGTPLVVSGGVDSALDPWGWVSQIASGRISTATDPDRAYLPFDERAAGY 233 Query: 180 TDLNKKLVQELLL-CSAELSEFTTVVGNTM-CTLDF--YEGQGRLDGA 223 + L +AE G C F G GR G Sbjct: 234 VPGEGGAILVLEDSAAAEARGRHDAYGELAGCASTFDPAPGSGRPAGL 281 >2J98-A nrPDB Length = 109 Score = 30.6 bits (67), Expect = 0.98, Method: Composition-based stats. Identities = 13/60 (21%), Positives = 22/60 (36%) Query: 205 GNTMCTLDFYEGQGRLDGALCSYTEKDKQAYLEAAYAAGVRNIEMESSVFAAMCSACGLQ 264 G T Y +G T K Y++ + +GV +E+E + + G Q Sbjct: 21 GITSEGNALYNNEGGRAFMYAYVTTKPGMKYVKWEHDSGVVTVELEPPARFVIDTPTGPQ 80 >1O4S-A nrPDB Length = 389 Score = 30.2 bits (66), Expect = 1.1, Method: Composition-based stats. Identities = 26/128 (20%), Positives = 48/128 (37%), Gaps = 16/128 (12%) Query: 113 PSISIMLHELIKLLY-----YARCSNVTIIRIGTSGGIG------LEPGTVVITEQAVDT 161 P+ ++ E ++ L Y + +R G + IG + P VV+T A Sbjct: 54 PTPEPVVEEAVRFLQKGEVKYTDPRGIYELREGIAKRIGERYKKDISPDQVVVTNGAKQA 113 Query: 162 CFKAEFEQIVLGKRVIRKTDLNKKLVQELLLCSAELSEFTTVVGNTMCTLDFYEGQGRLD 221 F A + G VI + + + +++L T V T + +F ++ Sbjct: 114 LFNAFMALLDPGDEVIVFSPVWVSYIPQIILA-----GGTVNVVETFMSKNFQPSLEEVE 168 Query: 222 GALCSYTE 229 G L T+ Sbjct: 169 GLLVGKTK 176 >3C8E-A nrPDB Length = 288 Score = 29.5 bits (64), Expect = 1.8, Method: Composition-based stats. Identities = 15/52 (28%), Positives = 27/52 (51%), Gaps = 8/52 (15%) Query: 110 MGIPS---ISIMLHELIKLLYYARCSNVTIIRIG-----TSGGIGLEPGTVV 153 +G P+ ++IML EL+ L + +IRIG +SG + + P + + Sbjct: 50 LGTPNGQKVTIMLEELLALGVTGAEYDAWLIRIGDGDQFSSGFVEVNPNSKI 101 >3LGS-A nrPDB Length = 267 Score = 29.1 bits (63), Expect = 2.7, Method: Composition-based stats. Identities = 19/87 (21%), Positives = 29/87 (33%), Gaps = 3/87 (3%) Query: 107 SHGMGIPSISIMLHELIKLLYYARCSNVTIIRIGTSGGIGL---EPGTVVITEQAVDTCF 163 +GI S+ + LI II GT GG + G V + V Sbjct: 82 DAALGIDSVGTVPASLITFASIQALKPDIIINAGTCGGFKVKGANIGDVFLVSDVVFHDR 141 Query: 164 KAEFEQIVLGKRVIRKTDLNKKLVQEL 190 + L +R+ L++EL Sbjct: 142 RIPIPMFDLYGVGLRQAFSTPNLLKEL 168 >3EEI-A nrPDB Length = 233 Score = 27.9 bits (60), Expect = 5.9, Method: Composition-based stats. Identities = 35/250 (14%), Positives = 80/250 (32%), Gaps = 31/250 (12%) Query: 65 MKAFIRCVGAELGLDCPGRDYPNICA-GTDRYAMYKVG----PVLSVSHGMGIPSISIML 119 +K E ++ N+ A R++ Y+ ++ G+G + ++ Sbjct: 3 LKTVAVIGAMEQEIELLREMMENVKAVSFGRFSAYEGELAGKRMVLALSGIGKVNAAVAT 62 Query: 120 HELIKLLYYARCSNVTIIRIGTSGGIGLEPG--TVVITEQAVDTCFKAEFEQIVLGKRVI 177 +I+ + A C +I G++GG+G VVI + G+ Sbjct: 63 AWIIR-EFAADC----VINTGSAGGLGKGLKVGDVVIGTETAHHDVDVTAFGYAWGQVPQ 117 Query: 178 --RKTDLNKKLVQELLLCSAELSEFTTVVGNTMCTLDFYEGQGRLDGALCSYTEKDKQAY 235 + + L++ + G + F + + K Sbjct: 118 LPARFASDGILIEAAKRAARTFEGAAVEQGLIVSGDRFVHSSEGV-----AEIRKHFPE- 171 Query: 236 LEAAYAAGVRNIEMESSVFAAMCSACGLQAAVVCVTLLNRLEGDQISSPRNV-LSEYQQR 294 V+ +EME++ A C L+ V + ++ ++ + L Sbjct: 172 --------VKAVEMEAAAIAQTCHQ--LETPFVIIRAVSDSADEKADISFDEFLKTAAAN 221 Query: 295 PQRLVSYFIK 304 ++V+ +K Sbjct: 222 SAKMVAEIVK 231 >6DZ3-A nrPDB Length = 297 Score = 27.5 bits (59), Expect = 7.1, Method: Composition-based stats. Identities = 23/94 (24%), Positives = 41/94 (43%), Gaps = 13/94 (13%) Query: 129 ARCSNVTIIRIGTSGGIGLEPGTVV--ITEQAVDTCFKAEFEQIVLGKR----------- 175 A + T ++IG GG GL+ ++ TE+ VDT F + ++LGK Sbjct: 16 ASGTTTTAVKIGIIGGTGLDDPEILEGRTEKYVDTPFGKPSDALILGKIKNVDCVLLARH 75 Query: 176 VIRKTDLNKKLVQELLLCSAELSEFTTVVGNTMC 209 + T + K+ + + + + T V+ T C Sbjct: 76 GRQHTIMPSKVNYQANIWALKEEGCTHVIVTTAC 109 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.308 0.117 0.280 Lambda K H 0.267 0.0360 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 9,086,151 Number of Sequences: 36641 Number of extensions: 303653 Number of successful extensions: 949 Number of sequences better than 10.0: 49 Number of HSP's better than 10.0 without gapping: 58 Number of HSP's successfully gapped in prelim test: 28 Number of HSP's that attempted gapping in prelim test: 758 Number of HSP's gapped (non-prelim): 94 length of query: 310 length of database: 10,336,785 effective HSP length: 97 effective length of query: 213 effective length of database: 6,782,608 effective search space: 1444695504 effective search space used: 1444695504 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 58 (27.1 bits)