BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q16773 (422 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 3FVS-A nrPDB 880 0.0 4WP0-A nrPDB 879 0.0 2ZJG-A nrPDB 479 e-136 1YIY-A nrPDB 407 e-114 3B46-A nrPDB 240 1e-63 1V2E-A nrPDB 216 2e-56 1U08-A nrPDB 214 4e-56 2O0R-A nrPDB 207 8e-54 1GC4-A nrPDB 187 1e-47 1GDE-A nrPDB 176 2e-44 5WMH-A nrPDB 159 3e-39 1O4S-A nrPDB 154 8e-38 6F35-A nrPDB 152 3e-37 6F77-B nrPDB 150 1e-36 1J32-A nrPDB 147 1e-35 4MY5-A nrPDB 137 8e-33 2Z61-A nrPDB 136 2e-32 1XI9-A nrPDB 122 4e-28 5YHV-A nrPDB 117 9e-27 2X5D-A nrPDB 110 1e-24 3H14-A nrPDB 105 3e-23 4IX8-A nrPDB 103 1e-22 2GB3-A nrPDB 101 5e-22 3ELE-A nrPDB 94 8e-20 1BW0-A nrPDB 91 7e-19 3PDX-A nrPDB 91 1e-18 4CVQ-A nrPDB 90 2e-18 3NRA-A nrPDB 88 7e-18 3DYD-A nrPDB 86 2e-17 3B1C-A nrPDB 84 9e-17 3T32-A nrPDB 84 1e-16 2ZC0-A nrPDB 83 3e-16 4DQ6-A nrPDB 79 3e-15 1IAY-A nrPDB 79 4e-15 2DOU-A nrPDB 78 9e-15 3L8A-A nrPDB 77 1e-14 3JTX-A nrPDB 73 2e-13 2O1B-A nrPDB 73 2e-13 1M4N-A nrPDB 70 1e-12 1X0M-A nrPDB 69 3e-12 3AV7-A nrPDB 69 3e-12 3OP7-A nrPDB 64 1e-10 1VP4-A nrPDB 64 1e-10 5Z0Q-C nrPDB 64 1e-10 3EZS-A nrPDB 61 1e-09 4FL0-A nrPDB 60 2e-09 4M2J-A nrPDB 60 3e-09 1C7O-A nrPDB 59 3e-09 3F6T-A nrPDB 58 9e-09 1WST-A nrPDB 56 3e-08 2ZY3-A nrPDB 55 6e-08 1D2F-A nrPDB 54 1e-07 3DZZ-A nrPDB 51 8e-07 3FDD-A nrPDB 51 9e-07 3IF2-A nrPDB 51 1e-06 4R2N-A nrPDB 50 1e-06 3ASB-A nrPDB 50 2e-06 3FDB-A nrPDB 49 6e-06 3EI8-A nrPDB 48 1e-05 3G0T-A nrPDB 47 1e-05 4GDY-A nrPDB 47 2e-05 3HDO-A nrPDB 47 2e-05 2ZY2-A nrPDB 46 2e-05 2ZYJ-A nrPDB 45 4e-05 3TCM-A nrPDB 45 6e-05 3G7Q-A nrPDB 44 2e-04 3QGU-A nrPDB 43 2e-04 1UU1-A nrPDB 42 4e-04 5DJ3-A nrPDB 42 4e-04 3GET-A nrPDB 41 0.001 1IJI-A nrPDB 40 0.002 1LC8-A nrPDB 40 0.003 6HNV-A nrPDB 38 0.008 3UWC-A nrPDB 38 0.008 3IHJ-A nrPDB 38 0.010 4K2M-A nrPDB 37 0.012 6HNB-A nrPDB 37 0.013 6C3C-A nrPDB 37 0.017 5K8B-A nrPDB 35 0.047 4JE5-A nrPDB 35 0.048 3P1T-A nrPDB 35 0.056 4L0O-H nrPDB 33 0.19 3MKJ-A nrPDB 33 0.21 3NYS-A nrPDB 32 0.36 2X5F-A nrPDB 32 0.37 2FNU-A nrPDB 32 0.39 6CJB-A nrPDB 32 0.44 4EMY-A nrPDB 32 0.55 3EUC-A nrPDB 32 0.68 6CC2-A nrPDB 32 0.73 3FTB-A nrPDB 31 0.89 3VK2-A nrPDB 30 1.3 1UTY-A nrPDB 30 1.5 5Y2C-A nrPDB 30 2.5 5ZVG-B nrPDB 29 3.1 4IYO-A nrPDB 29 4.9 5TSU-A nrPDB 28 5.9 3RQ1-A nrPDB 28 7.3 6ERK-A nrPDB 28 8.5 >3FVS-A nrPDB Length = 422 Score = 880 bits (2275), Expect = 0.0, Method: Compositional matrix adjust. Identities = 422/422 (100%), Positives = 422/422 (100%) Query: 1 MAKQLQARRLDGIDYNPWVEFVKLASEHDVVNLGQGFPDFPPPDFAVEAFQHAVSGDFML 60 MAKQLQARRLDGIDYNPWVEFVKLASEHDVVNLGQGFPDFPPPDFAVEAFQHAVSGDFML Sbjct: 1 MAKQLQARRLDGIDYNPWVEFVKLASEHDVVNLGQGFPDFPPPDFAVEAFQHAVSGDFML 60 Query: 61 NQYTKTFGYPPLTKILASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVII 120 NQYTKTFGYPPLTKILASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVII Sbjct: 61 NQYTKTFGYPPLTKILASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVII 120 Query: 121 IEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVL 180 IEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVL Sbjct: 121 IEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVL 180 Query: 181 NTPNNPLGKVFSREELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTL 240 NTPNNPLGKVFSREELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTL Sbjct: 181 NTPNNPLGKVFSREELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTL 240 Query: 241 TIGSAGKTFSATGWKVGWVLGPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFR 300 TIGSAGKTFSATGWKVGWVLGPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFR Sbjct: 241 TIGSAGKTFSATGWKVGWVLGPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFR 300 Query: 301 QPSSYFVQFPQAMQRCRDHMIRSLQSVGLKPIIPQGSYFLITDISDFKRKMPDLPGAVDE 360 QPSSYFVQFPQAMQRCRDHMIRSLQSVGLKPIIPQGSYFLITDISDFKRKMPDLPGAVDE Sbjct: 301 QPSSYFVQFPQAMQRCRDHMIRSLQSVGLKPIIPQGSYFLITDISDFKRKMPDLPGAVDE 360 Query: 361 PYDRRFVKWMIKNKGLVAIPVSIFYSVPHQKHFDHYIRFCFVKDEATLQAMDEKLRKWKV 420 PYDRRFVKWMIKNKGLVAIPVSIFYSVPHQKHFDHYIRFCFVKDEATLQAMDEKLRKWKV Sbjct: 361 PYDRRFVKWMIKNKGLVAIPVSIFYSVPHQKHFDHYIRFCFVKDEATLQAMDEKLRKWKV 420 Query: 421 EL 422 EL Sbjct: 421 EL 422 >4WP0-A nrPDB Length = 472 Score = 879 bits (2272), Expect = 0.0, Method: Compositional matrix adjust. Identities = 422/422 (100%), Positives = 422/422 (100%) Query: 1 MAKQLQARRLDGIDYNPWVEFVKLASEHDVVNLGQGFPDFPPPDFAVEAFQHAVSGDFML 60 MAKQLQARRLDGIDYNPWVEFVKLASEHDVVNLGQGFPDFPPPDFAVEAFQHAVSGDFML Sbjct: 1 MAKQLQARRLDGIDYNPWVEFVKLASEHDVVNLGQGFPDFPPPDFAVEAFQHAVSGDFML 60 Query: 61 NQYTKTFGYPPLTKILASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVII 120 NQYTKTFGYPPLTKILASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVII Sbjct: 61 NQYTKTFGYPPLTKILASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVII 120 Query: 121 IEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVL 180 IEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVL Sbjct: 121 IEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVL 180 Query: 181 NTPNNPLGKVFSREELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTL 240 NTPNNPLGKVFSREELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTL Sbjct: 181 NTPNNPLGKVFSREELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTL 240 Query: 241 TIGSAGKTFSATGWKVGWVLGPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFR 300 TIGSAGKTFSATGWKVGWVLGPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFR Sbjct: 241 TIGSAGKTFSATGWKVGWVLGPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFR 300 Query: 301 QPSSYFVQFPQAMQRCRDHMIRSLQSVGLKPIIPQGSYFLITDISDFKRKMPDLPGAVDE 360 QPSSYFVQFPQAMQRCRDHMIRSLQSVGLKPIIPQGSYFLITDISDFKRKMPDLPGAVDE Sbjct: 301 QPSSYFVQFPQAMQRCRDHMIRSLQSVGLKPIIPQGSYFLITDISDFKRKMPDLPGAVDE 360 Query: 361 PYDRRFVKWMIKNKGLVAIPVSIFYSVPHQKHFDHYIRFCFVKDEATLQAMDEKLRKWKV 420 PYDRRFVKWMIKNKGLVAIPVSIFYSVPHQKHFDHYIRFCFVKDEATLQAMDEKLRKWKV Sbjct: 361 PYDRRFVKWMIKNKGLVAIPVSIFYSVPHQKHFDHYIRFCFVKDEATLQAMDEKLRKWKV 420 Query: 421 EL 422 EL Sbjct: 421 EL 422 >2ZJG-A nrPDB Length = 410 Score = 479 bits (1234), Expect = e-136, Method: Compositional matrix adjust. Identities = 221/414 (53%), Positives = 292/414 (70%), Gaps = 4/414 (0%) Query: 6 QARRLDGIDYNPWVEFVKLASEHDVVNLGQGFPDFPPPDFAVEAFQHAVSGDFMLNQYTK 65 A+R++G+D N WVEF KLA++ VVNLGQGFPD PP + E A D M NQYT+ Sbjct: 1 NAKRIEGLDSNVWVEFTKLAADPSVVNLGQGFPDISPPSYVKEELSKAAFIDNM-NQYTR 59 Query: 66 TFGYPPLTKILASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFF 125 FG+P L K L+ +G++ ++IDP +LV VG YG+LF + Q LVD GDEVII+ PF+ Sbjct: 60 GFGHPALVKALSCLYGKIYQRQIDPNEEILVAVGAYGSLFNSIQGLVDPGDEVIIMVPFY 119 Query: 126 DCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNN 185 DCYEPM MAG PVF+ L+ P +G +SS+W DP EL KF+S+TKA++LNTP+N Sbjct: 120 DCYEPMVRMAGAVPVFIPLRSKP-TDGMKWTSSDWTFDPRELESKFSSKTKAIILNTPHN 178 Query: 186 PLGKVFSREELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTIGSA 245 PLGKV++R+EL+++A LC +HD +CI+DEVY+W+VY GH H+ IA+LPGMWERT+TIGSA Sbjct: 179 PLGKVYTRQELQVIADLCVKHDTLCISDEVYEWLVYTGHTHVKIATLPGMWERTITIGSA 238 Query: 246 GKTFSATGWKVGWVLGPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSY 305 GKTFS TGWK+GW +GP H++KHL+TV QNS + C T QAA+AE+F + P Y Sbjct: 239 GKTFSVTGWKLGWSIGPAHLIKHLQTVQQNSFYTCATPLQAALAEAFWIDIKRMDDPECY 298 Query: 306 FVQFPQAMQRCRDHMIRSLQSVGLKPIIPQGSYFLITDISDFKRKMPDLPGAVDEPYDRR 365 F P+ ++ RD M+R L SVGLKPI+P G YF+I D+S + D+ DEPYD + Sbjct: 299 FNSLPKELEVKRDRMVRLLNSVGLKPIVPDGGYFIIADVSSLGADLSDMNS--DEPYDYK 356 Query: 366 FVKWMIKNKGLVAIPVSIFYSVPHQKHFDHYIRFCFVKDEATLQAMDEKLRKWK 419 FVKWM K+K L AIPVS F + HF+ +RFCF+K ++TL A +E R W Sbjct: 357 FVKWMTKHKKLTAIPVSAFCDSKSKPHFEKLVRFCFIKKDSTLDAAEEIFRAWN 410 >1YIY-A nrPDB Length = 429 Score = 407 bits (1046), Expect = e-114, Method: Compositional matrix adjust. Identities = 200/413 (48%), Positives = 271/413 (65%), Gaps = 4/413 (0%) Query: 8 RRLDGIDYNPWVEFVKLASEHDVVNLGQGFPDFPPPDFAVEAFQHAV-SGDFMLNQYTKT 66 +R G + WVE+++LA+++ +NLGQGFPD+ P +A+ A A S D + NQYT+ Sbjct: 17 KRYQGSTKSVWVEYIQLAAQYKPLNLGQGFPDYHAPKYALNALAAAANSPDPLANQYTRG 76 Query: 67 FGYPPLTKILASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFD 126 FG+P L + L+ + +L+ + I+P+ VLVTVG Y AL+ Q VDEGDEVIIIEPFFD Sbjct: 77 FGHPRLVQALSKLYSQLVDRTINPMTEVLVTVGAYEALYATIQGHVDEGDEVIIIEPFFD 136 Query: 127 CYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNP 186 CYEPM AGG P F+ LKP + G SS++W LD EL F +TK +++NTP+NP Sbjct: 137 CYEPMVKAAGGIPRFIPLKPN--KTGGTISSADWVLDNNELEALFNEKTKMIIINTPHNP 194 Query: 187 LGKVFSREELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTIGSAG 246 LGKV R ELE+VA+LC++ +V+C++DEVY+ MV++ +HI I +LPGMWERT+TIGSAG Sbjct: 195 LGKVMDRAELEVVANLCKKWNVLCVSDEVYEHMVFEPFEHIRICTLPGMWERTITIGSAG 254 Query: 247 KTFSATGWKVGWVLGPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYF 306 KTFS TGWK+GW GP+ ++K+L+ VHQN V+ C T Q A+A FE E + P YF Sbjct: 255 KTFSLTGWKIGWAYGPEALLKNLQMVHQNCVYTCATPIQEAIAVGFETELKRLKSPECYF 314 Query: 307 VQFPQAMQRCRDHMIRSLQSVGLKPIIPQGSYFLITDISDFKRKMPDLPGAVDEPYDRRF 366 + RD+M L VG+ P +PQG YF++ D S K+ DL D D RF Sbjct: 315 NSISGELMAKRDYMASFLAEVGMNPTVPQGGYFMVADWSSLDSKV-DLTQETDARKDYRF 373 Query: 367 VKWMIKNKGLVAIPVSIFYSVPHQKHFDHYIRFCFVKDEATLQAMDEKLRKWK 419 KWM K+ GL IP S FYS P++ + ++R+CF K + LQ E LRKWK Sbjct: 374 TKWMTKSVGLQGIPPSAFYSEPNKHLGEDFVRYCFFKKDENLQKAAEILRKWK 426 >3B46-A nrPDB Length = 447 Score = 240 bits (612), Expect = 1e-63, Method: Compositional matrix adjust. Identities = 141/403 (34%), Positives = 214/403 (53%), Gaps = 26/403 (6%) Query: 28 HDVVNLGQGFPDFPPPDFAVEAFQHAVSGDFMLNQYTKTFGYPPLTKILASFFGELLGQE 87 +++NLGQGF + PP FA++ Q A+ M+NQY+ T G P L L + + E Sbjct: 57 RELINLGQGFFSYSPPQFAIKEAQKALDIP-MVNQYSPTRGRPSLINSLIKLYSPIYNTE 115 Query: 88 IDPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPG 147 + NV VT G + + L++ GDEVI+ EPFFD Y P + GG+ V+V + P Sbjct: 116 LKA-ENVTVTTGANEGILSCLMGLLNAGDEVIVFEPFFDQYIPNIELCGGKVVYVPINPP 174 Query: 148 PIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQQHD 207 + W +D + TS+TKA+++NTP+NP+GKVF+REEL + ++C +H+ Sbjct: 175 KELDQRNTRGEEWTIDFEQFEKAITSKTKAVIINTPHNPIGKVFTREELTTLGNICVKHN 234 Query: 208 VVCITDEVYQWMVY-DGHQHISIASLPGMWERTLTIGSAGKTFSATGWKVGWVLGPD-HI 265 VV I+DEVY+ + + D I+ S P + + TLT+GSAGK+F+ATGW++GWVL + + Sbjct: 235 VVIISDEVYEHLYFTDSFTRIATLS-PEIGQLTLTVGSAGKSFAATGWRIGWVLSLNAEL 293 Query: 266 MKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFPQAMQRCRDHMIRSLQ 325 + + H F P+ Q A A S + YF + Q Sbjct: 294 LSYAAKAHTRICFASPSPLQEACANSINDALKI-----GYFEKMRQEYINKFKIFTSIFD 348 Query: 326 SVGLKPIIPQGSYFLITDISDFKRKMPDLPGAVDEPY---------DRRFVKWMIKNKGL 376 +GL P+G+YF++ D S K K+P+ D PY D R W+I G+ Sbjct: 349 ELGLPYTAPEGTYFVLVDFS--KVKIPE-----DYPYPEEILNKGKDFRISHWLINELGV 401 Query: 377 VAIPVSIFYSVPHQKHFDHYIRFCFVKDEATLQAMDEKLRKWK 419 VAIP + FY H+K ++ +RF KD+A L+ E+L+ K Sbjct: 402 VAIPPTEFYIKEHEKAAENLLRFAVCKDDAYLENAVERLKLLK 444 >1V2E-A nrPDB Length = 381 Score = 216 bits (549), Expect = 2e-56, Method: Compositional matrix adjust. Identities = 142/396 (35%), Positives = 195/396 (49%), Gaps = 56/396 (14%) Query: 24 LASEHDVVNLGQGFPDFPPPDFAVEAFQHAVSGDFMLNQYTKTFGYPPLTKILASFFGEL 83 LA VNLGQGFP PPP F +EA + A+ +QY G P L + LA F Sbjct: 21 LAQRLGAVNLGQGFPSNPPPPFLLEAVRRALGRQ---DQYAPPAGLPALREALAEEFA-- 75 Query: 84 LGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVS 143 ++P +V+VT G AL+ Q+LV GDEV+++EPFFD Y P +AG + V Sbjct: 76 ----VEP-ESVVVTSGATEALYVLLQSLVGPGDEVVVLEPFFDVYLPDAFLAGAKARLVR 130 Query: 144 LKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASLC 203 L P ++LD L T RT+AL+LNTP NP G VF ELE +A L Sbjct: 131 LDLTP---------EGFRLDLSALEKALTPRTRALLLNTPMNPTGLVFGERELEAIARLA 181 Query: 204 QQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTIGSAGKTFSATGWKVGWVLGPD 263 + HD+ I+DEVY + Y P ERT T+GSAGK ATG++VGW++GP Sbjct: 182 RAHDLFLISDEVYDELYYGERPRRLREFAP---ERTFTVGSAGKRLEATGYRVGWIVGPK 238 Query: 264 HIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFPQAMQRCRDHMIRS 323 M L + Q + F PT QA VAE+ + L R+ ++ + +R RD + Sbjct: 239 EFMPRLAGMRQWTSFSAPTPLQAGVAEALK----LARR-EGFYEALREGYRRRRDLLAGG 293 Query: 324 LQSVGLKPIIPQGSYFLITDISDFKRKMPDLPGAVDEPYDRRFVKW----MIKNKGLVAI 379 L+++GL+ +P+G+YFL M +LPG W +++ + I Sbjct: 294 LRAMGLRVYVPEGTYFL----------MAELPG------------WDAFRLVEEARVALI 331 Query: 380 PVSIFYSVPHQKHFDHYIRFCFVKDEATLQAMDEKL 415 P S FY K RF F K E L E+L Sbjct: 332 PASAFYLEDPPKDL---FRFAFCKTEEELHLALERL 364 >1U08-A nrPDB Length = 386 Score = 214 bits (546), Expect = 4e-56, Method: Compositional matrix adjust. Identities = 128/401 (31%), Positives = 202/401 (50%), Gaps = 36/401 (8%) Query: 18 WVEFVKLASEHDVVNLGQGFPDFPPPDFAVEAFQHAVSGDFMLNQYTKTFGYPPLTKILA 77 + + LA +H +NL QGFPDF P + E H V+ NQY G L + +A Sbjct: 20 FTQMSALAQQHQAINLSQGFPDFDGPRYLQERLAHHVAQG--ANQYAPMTGVQALREAIA 77 Query: 78 SFFGELLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGG 137 L G + D ++ VT G AL+ A ALV GDEVI +P +D Y P ++GG Sbjct: 78 QKTERLYGYQPDADSDITVTAGATEALYAAITALVRNGDEVICFDPSYDSYAPAIALSGG 137 Query: 138 RPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELE 197 ++L+P ++++D E A + RT+ ++LNTP+NP V+ + + Sbjct: 138 IVKRMALQP-----------PHFRVDWQEFAALLSERTRLVILNTPHNPSATVWQQADFA 186 Query: 198 LVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTIGSAGKTFSATGWKVG 257 + H++ I+DEVY+ + + H S+ + P + ER + + S GKT+ TGWKVG Sbjct: 187 ALWQAIAGHEIFVISDEVYEHINFSQQGHASVLAHPQLRERAVAVSSFGKTYHMTGWKVG 246 Query: 258 WVLGPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFPQAMQRCR 317 + + P I +R VHQ F T +Q A+A+ + R +++ P ++ R Sbjct: 247 YCVAPAPISAEIRKVHQYLTFSVNTPAQLALAD-------MLRAEPEHYLALPDFYRQKR 299 Query: 318 DHMIRSLQSVGLKPIIPQGSYFLITDISDFKRKMPDLPGAVDEPYDRRFVKWMIKNKGLV 377 D ++ +L L+ + +G+YFL+ D S AV D F +W+ + G+ Sbjct: 300 DILVNALNESRLEILPCEGTYFLLVDYS-----------AVSTLDDVEFCQWLTQEHGVA 348 Query: 378 AIPVSIFYSVPHQKHFDH-YIRFCFVKDEATLQAMDEKLRK 417 AIP+S+F + P F H IR CF K E+TL A E+LR+ Sbjct: 349 AIPLSVFCADP----FPHKLIRLCFAKKESTLLAAAERLRQ 385 >2O0R-A nrPDB Length = 411 Score = 207 bits (527), Expect = 8e-54, Method: Compositional matrix adjust. Identities = 137/409 (33%), Positives = 199/409 (48%), Gaps = 38/409 (9%) Query: 18 WVEFVKLASEHDVVNLGQGFPDFPPPDFAVEAFQHAVSGDFMLNQYTKTFGYPPLTKILA 77 + E LA+ VNLGQGFPD P ++A Q A++G +NQY G PL + +A Sbjct: 15 FAEMSALATRIGAVNLGQGFPDEDGPPKMLQAAQDAIAGG--VNQYPPGPGSAPLRRAIA 72 Query: 78 SFFGELLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGG 137 + G + DP VLVTVG A+ A LV+ G EV++IEPF+D Y P+ MAG Sbjct: 73 AQRRRHFGVDYDPETEVLVTVGATEAIAAAVLGLVEPGSEVLLIEPFYDSYSPVVAMAGA 132 Query: 138 RPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELE 197 V V L P + LD L T RT+AL++N+P+NP G V S EL Sbjct: 133 HRVTVPLVP---------DGRGFALDADALRRAVTPRTRALIINSPHNPTGAVLSATELA 183 Query: 198 LVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTIGSAGKTFSATGWKVG 257 +A + ++V ITDEVY+ +V+D +H+ +A GM ERT+TI SA K F+ TGWK+G Sbjct: 184 AIAEIAVAANLVVITDEVYEHLVFDHARHLPLAGFDGMAERTITISSAAKMFNCTGWKIG 243 Query: 258 WVLGPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFPQAMQRCR 317 W GP ++ +R Q + Q AVA + + E ++ +++ R Sbjct: 244 WACGPAELIAGVRAAKQYLSYVGGAPFQPAVALALDTED-------AWVAALRNSLRARR 296 Query: 318 DHMIRSLQSVGLKPIIPQGSYFLITDISDFKRKMPDLPGAVDEPYDRRFVKWMIKNKGLV 377 D + L +G G+YFL D P + F + + G+ Sbjct: 297 DRLAAGLTEIGFAVHDSYGTYFLCAD-----------PRPLGYDDSTEFCAALPEKVGVA 345 Query: 378 AIPVSIFY------SVPHQKHFDHYIRFCFVKDEATLQAMDEKLRKWKV 420 AIP+S F + ++H +RF F K + TL DE +R+ V Sbjct: 346 AIPMSAFCDPAAGQASQQADVWNHLVRFTFCKRDDTL---DEAIRRLSV 391 >1GC4-A nrPDB Length = 385 Score = 187 bits (474), Expect = 1e-47, Method: Compositional matrix adjust. Identities = 124/392 (31%), Positives = 196/392 (50%), Gaps = 46/392 (11%) Query: 29 DVVNLGQGFPDFPPPDFAVEAFQHAVSGDFMLNQYTKTFGYPPLTKILASFFGELLGQEI 88 D+V L G PDF P+ EA + A++ +Y G P L + LA F G + Sbjct: 32 DLVALTAGEPDFDTPEHVKEAARRALAQG--KTKYAPPAGIPELREALAEKFRRENGLSV 89 Query: 89 DPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPGP 148 P +VTVGG ALF FQA++D GDEVI++ P++ Y M AGG V V P Sbjct: 90 TP-EETIVTVGGSQALFNLFQAILDPGDEVIVLSPYWVSYPEMVRFAGGVVVEVETLP-- 146 Query: 149 IQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQQHDV 208 + DP + T RTKALV+N+PNNP G V+ +E LE +A L +HD Sbjct: 147 --------EEGFVPDPERVRRAITPRTKALVVNSPNNPTGAVYPKEVLEALARLAVEHDF 198 Query: 209 VCITDEVYQWMVYDGHQHISIASLPGMW--ERTLTIGSAGKTFSATGWKVGWVLGPDHIM 266 ++DE+Y+ ++Y+G +H S PG E TLT+ A K F+ TGW++G+ GP ++ Sbjct: 199 YLVSDEIYEHLLYEG-EHFS----PGRVAPEHTLTVNGAAKAFAMTGWRIGYACGPKEVI 253 Query: 267 KHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFP-QAMQRCRDHMIRSLQ 325 K + +V + S T +Q A E+ L ++ S FV+ +A +R RD ++ L Sbjct: 254 KAMASVSRQSTTSPDTIAQWATLEA-----LTNQEASRAFVEMAREAYRRRRDLLLEGLT 308 Query: 326 SVGLKPIIPQGSYFLITDISDFKRKMPDLPGAVDEPYDRRFVKWMIKNKGLVAIPVSIFY 385 ++GLK + P G+++++ D S P + R + +++ G+ +P + F Sbjct: 309 ALGLKAVRPSGAFYVLMDTSPIA------------PDEVRAAERLLE-AGVAVVPGTDFA 355 Query: 386 SVPHQKHFDHYIRFCFVKDEATLQAMDEKLRK 417 + H +R + E L+ E+ + Sbjct: 356 AFGH-------VRLSYATSEENLRKALERFAR 380 >1GDE-A nrPDB Length = 389 Score = 176 bits (446), Expect = 2e-44, Method: Compositional matrix adjust. Identities = 119/397 (29%), Positives = 192/397 (48%), Gaps = 37/397 (9%) Query: 25 ASEHDVVNLGQGFPDFPPPDFAVEAFQHAVSGDFMLNQYTKTFGYPPLTKILASFFGELL 84 A DV++LG G PDF P E + A+ D L Y G L + +A + Sbjct: 23 AGMKDVISLGIGEPDFDTPQHIKEYAKEAL--DKGLTHYGPNIGLLELREAIAEKLKKQN 80 Query: 85 GQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVSL 144 G E DP ++V +G A A + +G+EV+I P F Y P ++AGG+PV V Sbjct: 81 GIEADPKTEIMVLLGANQAFLMGLSAFLKDGEEVLIPTPAFVSYAPAVILAGGKPVEVPT 140 Query: 145 KPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQ 204 ++L+ EL T +T+AL++N+P NP G V ++++LE +A Sbjct: 141 Y----------EEDEFRLNVDELKKYVTDKTRALIINSPCNPTGAVLTKKDLEEIADFVV 190 Query: 205 QHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTIGSAGKTFSATGWKVGWVLGPDH 264 +HD++ I+DEVY+ +YD +H SIASL GM+ERT+T+ KTF+ TGW++G+V P Sbjct: 191 EHDLIVISDEVYEHFIYDDARHYSIASLDGMFERTITVNGFSKTFAMTGWRLGFVAAPSW 250 Query: 265 IMKHLRTVHQNSVFHCP-TQSQAAVAESFEREQLLFRQPSSYFVQFPQAMQRCRDHMIRS 323 I++ + + CP T Q A A++ + E + + + R R + + Sbjct: 251 IIERMVKFQMYNA-TCPVTFIQYAAAKALKDE-----RSWKAVEEMRKEYDRRRKLVWKR 304 Query: 324 LQSVGLKPIIPQGSYFLITDISDFKRKMPDLPGAVDEPYDRRFVKWMIKNKGLVAIPVSI 383 L +GL + P+G++++ I D G ++F + M+K + +P S Sbjct: 305 LNEMGLPTVKPKGAFYIFPRIRD--------TGLT----SKKFSELMLKEARVAVVPGSA 352 Query: 384 FYSVPHQKHFDHYIRFCFVKD-EATLQAMDEKLRKWK 419 F K + Y+R + E +AMD R K Sbjct: 353 F-----GKAGEGYVRISYATAYEKLEEAMDRMERVLK 384 >5WMH-A nrPDB Length = 475 Score = 159 bits (401), Expect = 3e-39, Method: Compositional matrix adjust. Identities = 111/390 (28%), Positives = 181/390 (46%), Gaps = 28/390 (7%) Query: 30 VVNLGQGFPDFPPPDFAVEAFQHAVSGDFMLNQYTKTFGYPPLTKILASFFGELLGQEID 89 V+ L G PDF P EA +A+ F +YT G L + + E G Sbjct: 101 VIRLAAGEPDFDTPKVVAEAGINAIREGF--TRYTLNAGITELREAICRKLKEENGLSYA 158 Query: 90 PLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPI 149 P +LV+ G +L A A+ GDEVII P++ Y +A PV + P I Sbjct: 159 P-DQILVSNGAKQSLLQAVLAVCSPGDEVIIPAPYWVSYTEQARLADATPVVI---PTKI 214 Query: 150 QNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQQH-DV 208 N N+ LDP +L K T +++ L+L +P+NP G V+ + LE +A + +H + Sbjct: 215 SN-------NFLLDPKDLESKLTEKSRLLILCSPSNPTGSVYPKSLLEEIARIIAKHPRL 267 Query: 209 VCITDEVYQWMVYDGHQHISIASLPGMWERTLTIGSAGKTFSATGWKVGWVLGPDHIMKH 268 + ++DE+Y+ ++Y H S ASLP M+ERTLT+ K F+ TGW++G++ GP HI+ Sbjct: 268 LVLSDEIYEHIIYAPATHTSFASLPDMYERTLTVNGFSKAFAMTGWRLGYLAGPKHIVAA 327 Query: 269 LRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFPQAMQRCRDHMIRSLQSV- 327 + + +Q A + L + + +A + RD +++SL + Sbjct: 328 CSKLQGQVSSGASSIAQKAGVAALG----LGKAGGETVAEMVKAYRERRDFLVKSLGDIK 383 Query: 328 GLKPIIPQGSYFLITDISDFKRKMPDLPGAVDEPYDRRFVKWMIKNKGLVAIPVSIFYSV 387 G+K PQG+++L D S + + G +++ + + + +P F Sbjct: 384 GVKISEPQGAFYLFIDFSAYYGSEAEGFGLIND--SSSLALYFLDKFQVAMVPGDAFGD- 440 Query: 388 PHQKHFDHYIRFCFVKDEATLQAMDEKLRK 417 D IR + LQA EK+RK Sbjct: 441 ------DSCIRISYATSLDVLQAAVEKIRK 464 >1O4S-A nrPDB Length = 389 Score = 154 bits (389), Expect = 8e-38, Method: Compositional matrix adjust. Identities = 108/358 (30%), Positives = 180/358 (50%), Gaps = 41/358 (11%) Query: 28 HDVVNLGQGFPDFPPPDFAVE-AFQHAVSGDFMLNQYTKTFGYPPLTKILASFFGELLGQ 86 DV+NL G PDFP P+ VE A + G+ +YT G L + +A GE + Sbjct: 41 EDVINLTAGEPDFPTPEPVVEEAVRFLQKGEV---KYTDPRGIYELREGIAKRIGERYKK 97 Query: 87 EIDPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVSLKP 146 +I P V+VT G ALF AF AL+D GDEVI+ P + Y P ++AGG V Sbjct: 98 DISP-DQVVVTNGAKQALFNAFMALLDPGDEVIVFSPVWVSYIPQIILAGGTVNVV---- 152 Query: 147 GPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQQH 206 E S N+Q E+ G +TKA+++N+PNNP G V+ RE LE + L ++ Sbjct: 153 ------ETFMSKNFQPSLEEVEGLLVGKTKAVLINSPNNPTGVVYRREFLEGLVRLAKKR 206 Query: 207 DVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTIGSAGKTFSATGWKVGWVLGPDHIM 266 + I+DEVY +VY + SI + ++R + I K+ S TGW+VG+++ + + Sbjct: 207 NFYIISDEVYDSLVYT-DEFTSILDVSEGFDRIVYINGFSKSHSMTGWRVGYLISSEKVA 265 Query: 267 KHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFPQAMQRCRDHMIRSLQS 326 + + ++ T +Q A ++ E + +SY V Q + ++ ++ L+ Sbjct: 266 TAVSKIQSHTTSCINTVAQYAALKALEVD-------NSYMV---QTFKERKNFVVERLKK 315 Query: 327 VGLKPIIPQGSYFLITDISDFKRKMPDLPGAVDEPYDRRFVKWMIKNKGLVAIPVSIF 384 +G+K + P+G+++L FK + D+ +F + +++ K + +P S F Sbjct: 316 MGVKFVEPEGAFYLF-----FKVRGDDV----------KFCERLLEEKKVALVPGSAF 358 >6F35-A nrPDB Length = 410 Score = 152 bits (383), Expect = 3e-37, Method: Compositional matrix adjust. Identities = 108/391 (27%), Positives = 187/391 (47%), Gaps = 36/391 (9%) Query: 30 VVNLGQGFPDFPPPDFAVEAFQHAV-SGDFMLNQYTKTFGYPPLTKILASFFGELLGQEI 88 V+ LG G PDF P+ +A A+ G+ +YT G P L K + F G Sbjct: 43 VIILGAGEPDFDTPEHVKQAASDAIHRGE---TKYTALDGTPELKKAIREKFQRENGLAY 99 Query: 89 DPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPGP 148 + L + V G LF A A +D GDEVII P++ Y + + G+PV ++ Sbjct: 100 E-LDEITVATGAKQILFNAMMASLDPGDEVIIPTPYWTSYSDIVHICEGKPVLIACD--- 155 Query: 149 IQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELE-LVASLCQQHD 207 +SS ++L +L T RT+ ++LN+P+NP G +S + L+ L + Sbjct: 156 -------ASSGFRLTAEKLEAAITPRTRWVLLNSPSNPSGAAYSAADYRPLLEVLLRHPH 208 Query: 208 VVCITDEVYQWMVYDGHQHISIASL-PGMWERTLTIGSAGKTFSATGWKVGWVLGPDHIM 266 V + D++Y+ +VYDG + ++ A L PG+ RTLT+ K ++ TGW++G+ GP ++ Sbjct: 209 VWLLVDDMYEHIVYDGFRFVTPAQLEPGLKNRTLTVNGVSKAYAMTGWRIGYAGGPRELI 268 Query: 267 KHLRTVHQNSVFHCPTQ-SQAAVAESFEREQLLFRQPSSYFVQFPQAMQRCRDHMIRSLQ 325 K + V Q+ CP+ SQAA + P + + ++ QR RD ++ L Sbjct: 269 KAMAVV-QSQATSCPSSISQAASV-------VALNGPQDFLKERTESFQRRRDLVVNGLN 320 Query: 326 SV-GLKPIIPQGSYFLITDISDFKRKMPDLPGAVDEPYDRRFVKWMIKNKGLVAIPVSIF 384 ++ GL +P+G+++ + + K+ P D F +++++ + +P S F Sbjct: 321 AIDGLDCRVPEGAFYTFSGCAGVLGKV--TPSGKRIKTDTDFCAYLLEDAHVAVVPGSAF 378 Query: 385 YSVPHQKHFDHYIRFCFVKDEATLQAMDEKL 415 P + R + EA L+ E++ Sbjct: 379 GLSP-------FFRISYATSEAELKEALERI 402 >6F77-B nrPDB Length = 400 Score = 150 bits (379), Expect = 1e-36, Method: Compositional matrix adjust. Identities = 108/397 (27%), Positives = 187/397 (47%), Gaps = 32/397 (8%) Query: 25 ASEHDVVNLGQGFPDFPPPDFAVEAFQHAVSGDFMLNQYTKTFGYPPLTKILASFFGELL 84 A DV+ LG G PDF PD +A A+ D +YT G P L + +A F Sbjct: 28 AKGRDVIGLGAGEPDFDTPDNIKKAAIDAI--DRGETKYTPVSGIPELREAIAKKFKREN 85 Query: 85 GQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVSL 144 + + ++ T GG LF AF A ++ GDEV+I P++ Y M + GG PVFV Sbjct: 86 NLDYTAAQTIVGT-GGKQILFNAFMATLNPGDEVVIPAPYWVSYPEMVALCGGTPVFVPT 144 Query: 145 KPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQ 204 + +N++L +L T +TK V N+P+NP G +S EEL+ + + Sbjct: 145 R----------QENNFKLKAEDLDRAITPKTKWFVFNSPSNPSGAAYSHEELKALTDVLM 194 Query: 205 QH-DVVCITDEVYQWMVYDGHQHIS-IASLPGMWERTLTIGSAGKTFSATGWKVGWVLGP 262 +H V +TD++Y+ + Y + + + PG++ERTLT+ K ++ TGW++G+ GP Sbjct: 195 KHPHVWVLTDDMYEHLTYGDFRFATPVEVEPGLYERTLTMNGVSKAYAMTGWRIGYAAGP 254 Query: 263 DHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFPQAMQRCRDHMIR 322 H++K + + + +Q A E+ P + + + Q RD ++ Sbjct: 255 LHLIKAMDMIQGQQTSGAASIAQWAAVEA-------LNGPQDFIGRNKEIFQGRRDLVVS 307 Query: 323 SL-QSVGLKPIIPQGSYFLITDISDFKRKMPDLPGAVDEPYDRRFVKWMIKNKGLVAIPV 381 L Q+ G+ P+G++++ + K G V E D FV +++ +G+ + Sbjct: 308 MLNQAKGISCPTPEGAFYVYPSCAGLIGKTAP-SGKVIE-TDEDFVSELLETEGVAVVHG 365 Query: 382 SIFYSVPHQKHFDHYIRFCFVKDEATLQAMDEKLRKW 418 S F P+ R + EA L+ +++++ Sbjct: 366 SAFGLGPN-------FRISYATSEALLEEACRRIQRF 395 >1J32-A nrPDB Length = 388 Score = 147 bits (370), Expect = 1e-35, Method: Compositional matrix adjust. Identities = 106/396 (26%), Positives = 190/396 (47%), Gaps = 49/396 (12%) Query: 29 DVVNLGQGFPDFPPPDFAVEAFQHAVSGDFMLNQYTKTFGYPPLTKILASFF----GELL 84 DV + G PDF P VEA + A+ +Y G P L + +A G Sbjct: 31 DVCSFSAGEPDFNTPKHIVEAAKAALEQG--KTRYGPAAGEPRLREAIAQKLQRDNGLCY 88 Query: 85 GQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVSL 144 G + N+LVT GG ++F A+++ GDEVII PF+ Y M +A G PV + Sbjct: 89 GAD-----NILVTNGGKQSIFNLMLAMIEPGDEVIIPAPFWVSYPEMVKLAEGTPVIL-- 141 Query: 145 KPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQ 204 P ++ + +++ P ++ T +TK LV NTP+NP G V++ +E+ +A + Sbjct: 142 -PTTVE-------TQFKVSPEQIRQAITPKTKLLVFNTPSNPTGMVYTPDEVRAIAQVAV 193 Query: 205 QHDVVCITDEVYQWMVYDGHQHISI-ASLPGMWERTLTIGSAGKTFSATGWKVGWVLGPD 263 + + ++DE+Y+ ++YD QH+SI A+ P +ER++ KT++ TGW+VG++ GP Sbjct: 194 EAGLWVLSDEIYEKILYDDAQHLSIGAASPEAYERSVVCSGFAKTYAMTGWRVGFLAGPV 253 Query: 264 HIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFPQAMQRCRDHMIRS 323 ++K + +S + T +Q ++E Q ++ + F + R +M+ + Sbjct: 254 PLVKAATKIQGHSTSNVCTFAQYGAIAAYENSQDCVQEMLAAFAER-------RRYMLDA 306 Query: 324 LQSV-GLKPIIPQGSYFLITDISDFKRKMPDLPGAVDEPYDRRFVKWMIKNKGLVAIPVS 382 L ++ GL+ P G++++ I+ R D F ++ + +P + Sbjct: 307 LNAMPGLECPKPDGAFYMFPSIAKTGRSSLD------------FCSELLDQHQVATVPGA 354 Query: 383 IFYSVPHQKHFDHYIRFCFVKDEATLQAMDEKLRKW 418 F + D IR + D T++ E+L K+ Sbjct: 355 AFGA-------DDCIRLSYATDLDTIKRGMERLEKF 383 >4MY5-A nrPDB Length = 393 Score = 137 bits (345), Expect = 8e-33, Method: Compositional matrix adjust. Identities = 103/396 (26%), Positives = 185/396 (46%), Gaps = 48/396 (12%) Query: 29 DVVNLGQGFPDFPPPDFAVEAFQHAVSGDFMLNQYTKTFGYPPLTKILASFFGELLGQEI 88 DV+ L G PDF P EA + A+ D + YT G L + ++F E Sbjct: 33 DVLKLTLGEPDFATPKHIKEAAKRAIDAD--ESHYTGMAGLLALRQAASAFVKEKYHLTY 90 Query: 89 DPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPGP 148 +P +LVT+G AL + A+++ GD+V++ P + YEP+ + G V + + Sbjct: 91 NPDNEILVTIGATEALSASLTAILEPGDKVLLPAPAYPGYEPVVNLVGAEVVEIDTR--- 147 Query: 149 IQNGELGSSSNWQLDPM---ELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQQ 205 S+++ L P E K KA++LN P NP G +SR++++ +A + ++ Sbjct: 148 --------SNDFVLTPEMLEEAILKEGEALKAVILNYPTNPTGVTYSRQQIKNLAEVLKK 199 Query: 206 HDVVCITDEVYQWMVYDGHQHISIAS-LPGMWERTLTIGSAGKTFSATGWKVGWVLGPDH 264 + + I+DEVY + Y G H+SIA LP ++T+ I K+ + TGW++G + P Sbjct: 200 YPIFVISDEVYAELTYTGESHVSIAEYLP---DQTILISGLSKSHAMTGWRLGLIFAPAV 256 Query: 265 IMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFPQAMQRCRDHMIRSL 324 + L HQ V T Q A E+ + + + + RD++I + Sbjct: 257 LTAQLIKSHQYLVTAATTSVQFAAIEALTNGK-------DDALPMKEEYIKRRDYIIEKM 309 Query: 325 QSVGLKPIIPQGSYFLITDISDFKRKMPDLPGAVDEPYDR-RFVKWMIKNKGLVAIPVSI 383 +++ K I P G++++ K+P V + D +F++ K K + IP Sbjct: 310 EAMKFKIIKPDGAFYIFA-------KIP-----VAQGQDSFKFLQDFAKEKAVAFIP--- 354 Query: 384 FYSVPHQKHFDHYIRFCFVKDEATLQAMDEKLRKWK 419 V K+ + Y+R + A+++ + E +++ K Sbjct: 355 --GVAFGKYGEGYLRISYA---ASMETIKEAMKRLK 385 >2Z61-A nrPDB Length = 370 Score = 136 bits (342), Expect = 2e-32, Method: Compositional matrix adjust. Identities = 93/330 (28%), Positives = 166/330 (50%), Gaps = 35/330 (10%) Query: 23 KLASE-HDVVNLGQGFPDFPPPDFAV-EAFQHAVSGDFMLNQYTKTFGYPPLTKILASFF 80 KL SE V++L G PDF P V E + G YT + G L + ++ + Sbjct: 23 KLESEGKKVIHLEIGEPDFNTPKPIVDEGIKSLKEGK---THYTDSRGILELREKISELY 79 Query: 81 GELLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPV 140 + +I P N+++T G LF A +++D+GDEV+I P + CY+ G +PV Sbjct: 80 KDKYKADIIP-DNIIITGGSSLGLFFALSSIIDDGDEVLIQNPCYPCYKNFIRFLGAKPV 138 Query: 141 FVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVA 200 F ++ ++ +E A + +TKA+++N+P+NPLG+V RE + Sbjct: 139 FC----------------DFTVESLEEA--LSDKTKAIIINSPSNPLGEVIDRE----IY 176 Query: 201 SLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTIGSAGKTFSATGWKVGWVL 260 ++ I+DE+Y +VY+G + +I E+T+ I K ++ TGW++G+V+ Sbjct: 177 EFAYENIPYIISDEIYNGLVYEGKCYSAI-EFDENLEKTILINGFSKLYAMTGWRIGYVI 235 Query: 261 GPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFPQAMQRCRDHM 320 D I++ + + QN PT SQ A ++FE+E R+ +S +F R R + Sbjct: 236 SNDEIIEAILKLQQNLFISAPTISQYAALKAFEKETE--REINSMIKEF----DRRRRLV 289 Query: 321 IRSLQSVGLKPIIPQGSYFLITDISDFKRK 350 ++ ++ G + P G+Y++ +I + R+ Sbjct: 290 LKYVKDFGWEVNNPIGAYYVFPNIGEDGRE 319 >1XI9-A nrPDB Length = 406 Score = 122 bits (305), Expect = 4e-28, Method: Compositional matrix adjust. Identities = 91/327 (27%), Positives = 159/327 (48%), Gaps = 35/327 (10%) Query: 30 VVNLGQGFP---DFPPPDFAVEAFQHAVSGDFMLNQYTKTFGYPPLTKILASFFGELLGQ 86 V+ L G P DF PP+ EA+ A+ N Y + G P L K + G Sbjct: 40 VIRLNIGDPVKFDFQPPEHMKEAYCKAIKEGH--NYYGDSEGLPELRKAIVEREKRKNGV 97 Query: 87 EIDPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPV-FVSLK 145 +I P +V VT AL F AL+D GDE+++ P + Y + GG+PV + +++ Sbjct: 98 DITP-DDVRVTAAVTEALQLIFGALLDPGDEILVPGPSYPPYTGLVKFYGGKPVEYRTIE 156 Query: 146 PGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQQ 205 +WQ D ++ K T RTKA+ + PNNP G ++ ++ LE + ++ + Sbjct: 157 -----------EEDWQPDIDDIRKKITDRTKAIAVINPNNPTGALYDKKTLEEILNIAGE 205 Query: 206 HDVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTIGSAGKTFSATGWKVGWV--LGPD 263 +++ I+DE+Y M Y+G +HIS SL + + K + ATGW++G++ + P+ Sbjct: 206 YEIPVISDEIYDLMTYEG-EHISPGSLTKDVP-VIVMNGLSKVYFATGWRLGYMYFVDPE 263 Query: 264 HIMKHLRTVHQN--SVFHCP-TQSQ-AAVAESFEREQLLFRQPSSYFVQFPQAMQRCRDH 319 + + +R + CP T +Q AA+A P Y ++ + ++ RD+ Sbjct: 264 NKLSEVREAIDRLARIRLCPNTPAQFAAIAG--------LTGPMDYLKEYMKKLKERRDY 315 Query: 320 MIRSLQSV-GLKPIIPQGSYFLITDIS 345 + + L + G+ PQG++++ I Sbjct: 316 IYKRLNEIPGISTTKPQGAFYIFPKIE 342 >5YHV-A nrPDB Length = 394 Score = 117 bits (293), Expect = 9e-27, Method: Compositional matrix adjust. Identities = 103/410 (25%), Positives = 167/410 (40%), Gaps = 54/410 (13%) Query: 18 WVEFVKLASEH-DVVNLGQGFPDFPPPDFAVEAFQHAVSGDFMLNQ--YTKTFGYPPLTK 74 W+ + H D+VNL G P P E + A + LNQ Y+ G P L Sbjct: 26 WLAAAERQRTHGDLVNLSAGQPSAGAP----EPVRAAAAAALHLNQLGYSVALGIPELRD 81 Query: 75 ILASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTMM 134 +A+ + G ++P V++T G G AF A D GD V + P + CY + Sbjct: 82 AIAADYQRRHGITVEP-DAVVITTGSSGGFLLAFLACFDAGDRVAMASPGYPCYRNILSA 140 Query: 135 AGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSRE 194 G V + GP + + ++DP + +V+ +P NP G V E Sbjct: 141 LGCE--VVEIPCGPQTRFQPTAQMLAEIDP---------PLRGVVVASPANPTGTVIPPE 189 Query: 195 ELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERT---LTIGSAGKTFSA 251 EL +AS C DV I+DEVY +VY G S A W+ + + + S K ++ Sbjct: 190 ELAAIASWCDASDVRLISDEVYHGLVYQGAPQTSCA-----WQTSRNAVVVNSFSKYYAM 244 Query: 252 TGWKVGWVLGPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQP--SSYFVQF 309 TGW++GW+L P + + + + N P SQ A +F E +SY + Sbjct: 245 TGWRLGWLLVPTVLRRAVDCLTGNFTICPPVLSQIAAVSAFTPEATAEADGNLASYAIN- 303 Query: 310 PQAMQRCRDHMIRSLQSVGLKPIIP-QGSYFLITDISDFKRKMPDLPGAVDEPYDRRFVK 368 R ++ L+ +G+ + P G++++ D+SDF F Sbjct: 304 -------RSLLLDGLRRIGIDRLAPTDGAFYVYADVSDFTSD------------SLAFCS 344 Query: 369 WMIKNKGLVAIPVSIFYSVPHQKHFDHYIRFCFVKDEATLQAMDEKLRKW 418 ++ + G VAI I + F +R F ++ ++ W Sbjct: 345 KLLADTG-VAIAPGIDFDTARGGSF---VRISFAGPSGDIEEALRRIGSW 390 >2X5D-A nrPDB Length = 412 Score = 110 bits (275), Expect = 1e-24, Method: Compositional matrix adjust. Identities = 96/421 (22%), Positives = 182/421 (43%), Gaps = 49/421 (11%) Query: 1 MAKQLQARRLDGIDYNPWVEF-----VKLASEH---DVVNLGQGFPDFPPPDFAVEAFQH 52 MA+ ARR ID P F +K+A+ D+++L G PD P P VE Sbjct: 2 MAESRPARRFARIDRLPPYVFNITAELKMAARRRGEDIIDLSMGNPDGPTPPHIVEKL-C 60 Query: 53 AVSGDFMLNQYTKTFGYPPLTKILASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQALV 112 V+ + Y+ + G P L + ++ ++ + +IDP +VT+G L A + Sbjct: 61 TVAQREDTHGYSTSRGIPRLRRAISHWYRDRYDVQIDPESEAIVTIGSKEGLAHLMLATL 120 Query: 113 DEGDEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFT 172 D GD +++ P + + ++AG + V L PG EL + + Sbjct: 121 DHGDTILVPNPSYPIHIYGAVIAGAQVRSVPLVPGIDFFNELERAIRESI---------- 170 Query: 173 SRTKALVLNTPNNPLGKVFSREELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASL 232 + + ++L P+NP + + E V +L +Q+DV+ + D Y +VYDG + SI + Sbjct: 171 PKPRMMILGFPSNPTAQCVELDFFERVVALAKQYDVMVVHDLAYADIVYDGWKAPSIMQV 230 Query: 233 PGMWERTLTIGSAGKTFSATGWKVGWVLGPDHIMKHLRTVHQNSVFHCPTQSQAAVAESF 292 PG + + + K+++ GW++G+++G ++ L + + T Q A + Sbjct: 231 PGAKDIAVEFFTLSKSYNMAGWRIGFMVGNPELVSALARIKSYHDYGTFTPLQVAAIAAL 290 Query: 293 EREQLLFRQPSSYFVQFPQAMQRCRDHMIRSLQSVGLKPIIPQGSYFLITDISDFKRKMP 352 E +Q R + + Q+ RD +++ L+ G P+ S ++ I Sbjct: 291 EGDQQCVRDIARQY-------QQRRDVLVKGLREAGWMVENPKASMYVWAKIP------- 336 Query: 353 DLPGAVDEPYDR----RFVKWMIKNKGLVAIPVSIFYSVPHQKHFDHYIRFCFVKDEATL 408 EPY F K ++++ VS+ + + D ++RF +++ L Sbjct: 337 -------EPYAHLGSLEFAKKLLQDA-----KVSVSPGIGFGDYGDDHVRFALIENRDRL 384 Query: 409 Q 409 + Sbjct: 385 R 385 >3H14-A nrPDB Length = 391 Score = 105 bits (262), Expect = 3e-23, Method: Compositional matrix adjust. Identities = 93/390 (23%), Positives = 158/390 (40%), Gaps = 45/390 (11%) Query: 30 VVNLGQGFPDFPPPDFAVEAFQHAVSGDFMLNQYTKTFGYPPLTKILASFFGELLGQEID 89 ++++ G P P AVEA ++ D + YT G P L + +A +GE G ++D Sbjct: 33 IIHMEVGQPGTGAPRGAVEALAKSLETDAL--GYTVALGLPALRQRIARLYGEWYGVDLD 90 Query: 90 PLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPI 149 P R V++T G G AF AL D GD V I P + Y + G PV + P Sbjct: 91 PGR-VVITPGSSGGFLLAFTALFDSGDRVGIGAPGYPSYRQILRALGLVPVDLPTAP--- 146 Query: 150 QNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQQHDVV 209 + Q P + AG + L++ +P NP G + + + Q Sbjct: 147 -------ENRLQPVPADFAGLDLA---GLMVASPANPTGTMLDHAAMGALIEAAQAQGAS 196 Query: 210 CITDEVYQWMVYDGHQHISIASLPGMWERTLTIGSAGKTFSATGWKVGWVLGPDHIMKHL 269 I+DE+Y + Y+ ++ + + I S K FS TGW+VGW++ P+ ++ + Sbjct: 197 FISDEIYHGIEYEAKAVTALE----LTDECYVINSFSKYFSMTGWRVGWMVVPEDQVRVV 252 Query: 270 RTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFPQAMQRCRDHMIRSLQSVGL 329 + QN P SQ A + + + L Y + R M+ L G Sbjct: 253 ERIAQNMFICAPHASQVAALAALDCDAELQANLDVY--------KANRKLMLERLPKAGF 304 Query: 330 KPII-PQGSYFLITDISDFKRKMPDLPGAVDEPYDRRFVKWMIKNKGLVAIPVSIFYSVP 388 I P G++++ D+SD R F +++ G+ P F Sbjct: 305 TRIAPPDGAFYVYADVSDLTDD------------SRAFAAEILEKAGVAVTPGLDF---- 348 Query: 389 HQKHFDHYIRFCFVKDEATLQAMDEKLRKW 418 + +RF + + A ++ ++L + Sbjct: 349 DPERGAGTLRFSYARATADIEEGLDRLEAF 378 >4IX8-A nrPDB Length = 444 Score = 103 bits (258), Expect = 1e-22, Method: Compositional matrix adjust. Identities = 70/227 (30%), Positives = 102/227 (44%), Gaps = 18/227 (7%) Query: 39 DFPPPDFAVEAFQHAV-SGDFMLNQYTKTFGYPPLTKILASFFGELLG----QEIDPLRN 93 + PD EA V SG F N Y T G L +++++++ QE N Sbjct: 82 NLKTPDIVTEAMVDVVRSGKF--NGYPPTVGADNLRQVVSTYWRRFCQTKSRQEALKWEN 139 Query: 94 VLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGE 153 V++T G A+ A AL +EGD +++ P F Y+ + G + L P Sbjct: 140 VIITSGVSQAIVLALTALCNEGDNILVCAPSFPHYKSVCDSYGIECRYYYLDP------- 192 Query: 154 LGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQQHDVVCITD 213 S +W+ D AG S TKA V+ P+NP G FSR + + CQQH + I+D Sbjct: 193 ---SKSWECDLRAAAGMVDSHTKAFVIINPSNPCGSNFSRAHVSDIIDFCQQHQIPLISD 249 Query: 214 EVYQWMVYDGHQHISIASLPGMWERTLTIGSAGKTFSATGWKVGWVL 260 E+Y MV + S+A R L +G K GW+VGW + Sbjct: 250 EIYAEMVLNNGIFTSVADFDTNVPR-LILGGTAKYQVCPGWRVGWSI 295 >2GB3-A nrPDB Length = 409 Score = 101 bits (252), Expect = 5e-22, Method: Compositional matrix adjust. Identities = 90/349 (25%), Positives = 160/349 (45%), Gaps = 49/349 (14%) Query: 19 VEFVKLASEHDV----VNLGQGFPDFPPPDFAVEAFQHAVSGDFMLNQYTKTFGYPPLTK 74 V F ++A + V +N+GQ PD P+ F+ + Y+ + G L + Sbjct: 32 VPFAEMAKKRGVRIHHLNIGQ--PDLKTPEVF---FERIYENKPEVVYYSHSAGIWELRE 86 Query: 75 ILASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTMM 134 AS++ ++ P NVLVT GG A+ +F + + GDE++++EPF+ Y + Sbjct: 87 AFASYYKRRQRVDVKP-ENVLVTNGGSEAILFSFAVIANPGDEILVLEPFYANYNAFAKI 145 Query: 135 AGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSRE 194 AG + + V+ + E G + P L RTK +VL+ P NP G V+ ++ Sbjct: 146 AGVKLIPVT------RRMEEGFAI-----PQNLESFINERTKGIVLSNPCNPTGVVYGKD 194 Query: 195 ELELVASLCQQHDVVCITDEVYQWMVYDGH--QHISIASLPGMWERTLTIGSAGKTFSAT 252 E+ + + ++H + I DEVY +V+ G +SI S ++ + I S K FSA Sbjct: 195 EMRYLVEIAERHGLFLIVDEVYSEIVFRGEFASALSIES-----DKVVVIDSVSKKFSAC 249 Query: 253 GWKVGWVLGPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQL----LFRQPSSYFVQ 308 G +VG ++ T ++ + H +Q +A EQ+ L S+F Sbjct: 250 GARVGCLI----------TRNEELISHAMKLAQGRLAPPL-LEQIGSVGLLNLDDSFFDF 298 Query: 309 FPQAMQRCRDHMIRSLQSVGLKPII-PQGSYFL-----ITDISDFKRKM 351 + + + +++ L+ GLK P G++++ + D +F R M Sbjct: 299 VRETYRERVETVLKKLEEHGLKRFTKPSGAFYITAELPVEDAEEFARWM 347 >3ELE-A nrPDB Length = 398 Score = 94.4 bits (233), Expect = 8e-20, Method: Compositional matrix adjust. Identities = 78/326 (23%), Positives = 140/326 (42%), Gaps = 29/326 (8%) Query: 24 LASEHDVVNLGQGFPDFPPPDFAVEAFQHAVSG--DFMLNQYTKTFGYPPLTKILASFFG 81 + + +V + G P P P + + V+ L+ YT G +A F Sbjct: 31 IVGKENVYDFSIGNPSIPAPQIVNDTIKELVTDYDSVALHGYTSAQGDVETRAAIAEFLN 90 Query: 82 ELLGQEIDPLRNVLVTVGGYGALFTAFQALV-DEGDEVIIIEPFFDCYEPMTMMAGGRPV 140 G + N+ +T+G +L F+AL D DE I I P+F Y+ AG R V Sbjct: 91 NTHGTHFNA-DNLYMTMGAAASLSICFRALTSDAYDEFITIAPYFPEYKVFVNAAGARLV 149 Query: 141 FVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVA 200 V + ++Q+D L + + T+ +++N+PNNP G V+S E ++ ++ Sbjct: 150 EVP-----------ADTEHFQIDFDALEERINAHTRGVIINSPNNPSGTVYSEETIKKLS 198 Query: 201 SLCQQHD------VVCITDEVYQWMVYDGHQHISIASLPGMWERTLTIGSAGKTFSATGW 254 L ++ + I DE Y+ +VYDG I + + ++ TL S K+ S G Sbjct: 199 DLLEKKSKEIGRPIFIIADEPYREIVYDG---IKVPFVTKYYDNTLVCYSYSKSLSLPGE 255 Query: 255 KVGWVLGPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFPQAMQ 314 ++G+VL PD + +V A S ++ ++ Q ++ + A + Sbjct: 256 RIGYVLVPDEVYDKAELYA--AVCGAGRALGYVCAPSLFQKMIVKCQGATGDI---NAYK 310 Query: 315 RCRDHMIRSLQSVGLKPIIPQGSYFL 340 RD + L +G P G++++ Sbjct: 311 ENRDLLYEGLTRIGYHCFKPDGAFYM 336 >1BW0-A nrPDB Length = 416 Score = 91.3 bits (225), Expect = 7e-19, Method: Compositional matrix adjust. Identities = 66/263 (25%), Positives = 120/263 (45%), Gaps = 29/263 (11%) Query: 93 NVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNG 152 NV++ GG + A A+ D GD ++ +P F YE + G F + +P Sbjct: 106 NVVLCSGGSHGILMAITAICDAGDYALVPQPGFPHYETVCKAYGIGMHFYNCRP------ 159 Query: 153 ELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQQHDVVCIT 212 ++W+ D E+ +TK L++ P+NP G FSR+ +E + L ++ + + Sbjct: 160 ----ENDWEADLDEIRRLKDDKTKLLIVTNPSNPCGSNFSRKHVEDIVRLAEELRLPLFS 215 Query: 213 DEVYQWMVYDGHQHISIASLPGMWERT---LTIGSAGKTFSATGWKVGWVL-------GP 262 DE+Y MV+ G + + +E T + +G K GW++GW+L GP Sbjct: 216 DEIYAGMVFKGKDPNATFTSVADFETTVPRVILGGTAKNLVVPGWRLGWLLYVDPHGNGP 275 Query: 263 DHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFPQAMQRCRDHMIR 322 ++ L+ V C T QAA+ E+ L P + Q ++ ++ Sbjct: 276 S-FLEGLKRVGMLVCGPC-TVVQAALGEA------LLNTPQEHLDQIVAKIEESAMYLYN 327 Query: 323 SL-QSVGLKPIIPQGSYFLITDI 344 + + +GL P +P+G+ +L++ I Sbjct: 328 HIGECIGLAPTMPRGAMYLMSRI 350 >3PDX-A nrPDB Length = 402 Score = 90.9 bits (224), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 88/376 (23%), Positives = 162/376 (43%), Gaps = 43/376 (11%) Query: 22 VKLASEHDVVNLGQGFP----DFPPPDFAVEAFQHAV-SGDFMLNQYTKTFGYPPLTKIL 76 VK V++L G P + P +A + A+ SG + N Y + GY + + Sbjct: 25 VKPNPNKTVISLSIGDPTVFGNLPTDPEVTQAMKDALDSGKY--NGYAPSIGYLSSREEV 82 Query: 77 ASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAG 136 AS++ + ++V++T G A+ L + G ++I P F Y + G Sbjct: 83 ASYYH--CPEAPLEAKDVILTSGCSQAIELCLAVLANPGQNILIPRPGFSLYRTLAESMG 140 Query: 137 GRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREEL 196 +L P +W++D +L +T LV+N P+NP G VFS+ L Sbjct: 141 IEVKLYNLLP----------EKSWEIDLKQLESLIDEKTACLVVNNPSNPCGSVFSKRHL 190 Query: 197 ELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTIGSAGKTFSATGWKV 256 + + ++ ++ V + DE+Y MV+ ++ +A+L L+ G K + GW++ Sbjct: 191 QKILAVAERQCVPILADEIYGDMVFSDCKYEPMATL-STNVPILSCGGLAKRWLVPGWRL 249 Query: 257 GWVLGPD-------HIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQF 309 GW+L D I L + Q + C T Q A+ + +L R P ++ Sbjct: 250 GWILIHDRRDIFGNEIRDGLVKLSQRILGPC-TIVQGAL------KSILQRTPQEFYQDT 302 Query: 310 PQAMQRCRDHMIRSLQSV-GLKPIIPQGSYFLITDISDFKRKMPDLPGAVDEPYDRRFVK 368 ++ D +L ++ GL+P+ P G+ +L+ I +M P + D F + Sbjct: 303 LSFLKSNADLCYGALSAIPGLQPVRPSGAMYLMVGI-----EMEHFPEFEN---DVEFTE 354 Query: 369 WMIKNKGLVAIPVSIF 384 +I + + +P + F Sbjct: 355 RLIAEQSVHCLPATCF 370 >4CVQ-A nrPDB Length = 431 Score = 89.7 bits (221), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 49/171 (28%), Positives = 89/171 (52%), Gaps = 13/171 (7%) Query: 91 LRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPIQ 150 + ++ + G + A QAL++ GDE+++ P + + ++ G+ V Sbjct: 121 VEDIYIGNGVSELIVQAMQALLNSGDEMLVPAPDYPLWTAAVSLSSGKAVHYLCD----- 175 Query: 151 NGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQQHDVVC 210 SS+W D ++ K T RT+ +V+ PNNP G V+S+E L + + +QH+++ Sbjct: 176 -----ESSDWFPDLDDIRAKITPRTRGIVIINPNNPTGAVYSKELLMEIVEIARQHNLII 230 Query: 211 ITDEVYQWMVYDGHQHISIASL-PGMWERTLTIGSAGKTFSATGWKVGWVL 260 DE+Y ++YD +H SIA L P + T+T KT+ G++ GW++ Sbjct: 231 FADEIYDKILYDDAEHHSIAPLAPDLL--TITFNGLSKTYRVAGFRQGWMV 279 >3NRA-A nrPDB Length = 407 Score = 87.8 bits (216), Expect = 7e-18, Method: Compositional matrix adjust. Identities = 83/347 (23%), Positives = 136/347 (39%), Gaps = 32/347 (9%) Query: 60 LNQYTKTFGYPPLTKILASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVI 119 + YT+ G + +LA G +D +++T G GALF A A V GD+V Sbjct: 71 VQAYTEYRGDLGIRDLLAPRLAAFTGAPVDARDGLIITPGTQGALFLAVAATVARGDKVA 130 Query: 120 IIEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALV 179 I++P + + G V V L G LD L F + + + Sbjct: 131 IVQPDYFANRKLVEFFEGEMVPVQLDYVSADETRAG------LDLTGLEEAFKAGARVFL 184 Query: 180 LNTPNNPLGKVFSREELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGM-WER 238 + PNNP G V+S EE+ +A+L ++ I D++Y + Y G + + + + E Sbjct: 185 FSNPNNPAGVVYSAEEIGQIAALAARYGATVIADQLYSRLRYAGASYTHLRAEAAVDAEN 244 Query: 239 TLTIGSAGKTFSATGWKVGWVLGPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLL 298 +TI KT S +G+++G G I+ + + SQA + + Sbjct: 245 VVTIMGPSKTESLSGYRLGVAFGSRAIIARMEKLQAIVSLRAAGYSQAVL-------RGW 297 Query: 299 FRQPSSYFVQFPQAMQRCRDHMIRSLQSV-GLKPIIPQGSYFLITDISDFKRKMPDLPGA 357 F + + Q RD ++ L+ G+ PQ +L P LP Sbjct: 298 FDEAPGWMEDRIARHQAIRDELLHVLRGCEGVFARTPQAGSYL----------FPRLPKL 347 Query: 358 VDEPYDRRFVKWMIKNKGLVAIPVSIFYSVPHQKHFDHYIRFCFVKD 404 P + FVK + G+V P + F H +R F +D Sbjct: 348 AVAPAE--FVKILRLQAGVVVTPGTEF-----SPHTADSVRLNFSQD 387 >3DYD-A nrPDB Length = 427 Score = 86.3 bits (212), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 79/357 (22%), Positives = 155/357 (43%), Gaps = 39/357 (10%) Query: 37 FPDFPPPDFAVEAFQHAV-SGDFMLNQYTKTFGYPPLTKILASFFGELLGQEIDPLRNVL 95 F + P +A + A+ SG + N Y + G+ + +AS++ + ++V+ Sbjct: 67 FGNLPTDPEVTQAMKDALDSGKY--NGYAPSIGFLSSREEIASYYH--CPEAPLEAKDVI 122 Query: 96 VTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELG 155 +T G A+ L + G +++ P F Y+ + G +L P Sbjct: 123 LTSGCSQAIDLCLAVLANPGQNILVPRPGFSLYKTLAESMGIEVKLYNLLP--------- 173 Query: 156 SSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQQHDVVCITDEV 215 +W++D +L +T L++N P+NP G VFS+ L+ + ++ + V + DE+ Sbjct: 174 -EKSWEIDLKQLEYLIDEKTACLIVNNPSNPCGSVFSKRHLQKILAVAARQCVPILADEI 232 Query: 216 YQWMVYDGHQHISIASLPGMWERTLTIGSAGKTFSATGWKVGWVLGPDH-------IMKH 268 Y MV+ ++ +A+L L+ G K + GW++GW+L D I Sbjct: 233 YGDMVFSDCKYEPLATL-STDVPILSCGGLAKRWLVPGWRLGWILIHDRRDIFGNEIRDG 291 Query: 269 LRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFPQAMQRCRDHMIRSLQSV- 327 L + Q + C T Q A+ + +L R P ++ ++ D +L ++ Sbjct: 292 LVKLSQRILGPC-TIVQGAL------KSILCRTPGEFYHNTLSFLKSNADLCYGALAAIP 344 Query: 328 GLKPIIPQGSYFLITDISDFKRKMPDLPGAVDEPYDRRFVKWMIKNKGLVAIPVSIF 384 GL+P+ P G+ +L+ I +M P + D F + ++ + + +P + F Sbjct: 345 GLRPVRPSGAMYLMVGI-----EMEHFP---EFENDVEFTERLVAEQSVHCLPATCF 393 >3B1C-A nrPDB Length = 392 Score = 84.3 bits (207), Expect = 9e-17, Method: Compositional matrix adjust. Identities = 68/264 (25%), Positives = 121/264 (45%), Gaps = 26/264 (9%) Query: 92 RNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPIQN 151 +++ G A+ A QA EG+ V+I P + + + + V SLK +N Sbjct: 90 EDIVFVEGVVPAISIAIQAFTKEGEAVLINSPVYPPFARSVRLNNRKLVSNSLKE---EN 146 Query: 152 GELGSSSNWQLDPMELAGKFTSR-TKALVLNTPNNPLGKVFSREELELVASLCQQHDVVC 210 G +Q+D +L K +L P+NP G+V+ RE LE + LCQ+H V+ Sbjct: 147 GL------FQIDFEQLENDIVENDVKLYLLCNPHNPGGRVWEREVLEQIGHLCQKHHVIL 200 Query: 211 ITDEVYQWMVYDGHQHISIASL-PGMWERTLTIGSAGKTFSATGWKVGWVLGPDHIM--- 266 ++DE++Q + GH+H+S ++ P + L + SA KTF+ G K + + + + Sbjct: 201 VSDEIHQDLTLFGHEHVSFNTVSPDFKDFALVLSSATKTFNIAGTKNSYAIIENPTLCAQ 260 Query: 267 -KHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFPQAMQRCRDHMIR--S 323 KH + V+ H S +A + +R + V ++ + + Sbjct: 261 FKHQQLVNN----HHEVSSLGYIA-----TETAYRYGKPWLVALKAVLEENIQFAVEYFA 311 Query: 324 LQSVGLKPIIPQGSYFLITDISDF 347 ++ LK + PQG+Y + D SD+ Sbjct: 312 QEAPRLKVMKPQGTYLIWLDFSDY 335 >3T32-A nrPDB Length = 383 Score = 84.3 bits (207), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 65/261 (24%), Positives = 121/261 (46%), Gaps = 29/261 (11%) Query: 94 VLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGE 153 ++ + G AL T+ QA E + V++ P + + M + R + VS P+Q Sbjct: 85 IVFSAGIVPALSTSIQAFTKENESVLVQPPIYPPFFEM-VTTNNRQLCVS----PLQK-- 137 Query: 154 LGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQQHDVVCITD 213 + + +D L +F K ++L +P+NP+G+V+ +EEL + SLC +++V+ + D Sbjct: 138 --QNDTYAIDFEHLEKQFQQGVKLMLLCSPHNPIGRVWKKEELTKLGSLCTKYNVIVVAD 195 Query: 214 EVYQWMVYDGHQHISIASLP-GMWERTLTIGSAGKTFSATGWKVGWVLGPDHIMKHLRTV 272 E++ ++Y H H ASL + RT+T + KTF+ G + ++ P+ ++ T Sbjct: 196 EIHSDIIYADHTHTPFASLSEELAARTITCMAPSKTFNIAGLQASIIIIPNEKLRQAFTS 255 Query: 273 HQ--------NSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFPQAMQRCRDHMIRSL 324 Q N + QS + E + + ++ F A + +DH+ Sbjct: 256 IQYRQGFHGLNIFAYTAMQSAYTECNDWLNEIRFYIEDNAKF-----ACEYIKDHI---- 306 Query: 325 QSVGLKPIIPQGSYFLITDIS 345 L + P+GS+ L D S Sbjct: 307 --PTLSVMKPEGSFLLWIDCS 325 >2ZC0-A nrPDB Length = 407 Score = 82.8 bits (203), Expect = 3e-16, Method: Compositional matrix adjust. Identities = 81/344 (23%), Positives = 143/344 (41%), Gaps = 54/344 (15%) Query: 7 ARRLDGIDYNPWVEFVKLASEH-----DVVNLGQGFPDFPPPDFAVEAFQHAVSGDFMLN 61 A R + I + + +K ASE +++L G PD P+ A ++ + + Sbjct: 8 AGRANWIKGSALADVMKKASELQKKGVKLISLAAGDPD---PELIPRAVLGEIAKEVLEK 64 Query: 62 Q-----YTKTFGYPPLTKILASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGD 116 + YT G P L + LA+F + E+ P N+++T+GG GAL + L+D GD Sbjct: 65 EPKSVMYTPANGIPELREELAAFLKKYDHLEVSP-ENIVITIGGTGALDLLGRVLIDPGD 123 Query: 117 EVIIIEPFFD----CYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPME-----L 167 VI P + +E + G PV + ++D +E L Sbjct: 124 VVITENPSYINTLLAFEQLGAKIEGVPV---------------DNDGMRVDLLEEKIKEL 168 Query: 168 AGKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQQHDVVCITDEVYQWMVYDGHQHI 227 K + T NP+G S E + + + ++D++ I D Y +M Y+G + Sbjct: 169 KAKGQKVKLIYTIPTGQNPMGVTMSMERRKALLEIASKYDLLIIEDTAYNFMRYEGGDIV 228 Query: 228 SIASLPGMWERTLTIGSAGKTFSATGWKVGWVLGPDHIMKHLRTVHQNSVFHCPTQSQAA 287 + +L R + G+ K TG+++GW++ I+K + Q F P SQ Sbjct: 229 PLKALDNEG-RVIVAGTLSKVL-GTGFRIGWIIAEGEILKKVLMQKQPIDFCAPAISQYI 286 Query: 288 VAESFEREQLLFRQPSSYFVQFP-----QAMQRCRDHMIRSLQS 326 E +R YF ++ + RD M+++L++ Sbjct: 287 ALEYLKR---------GYFEKYHLEGALLGYKEKRDIMLKALEN 321 >4DQ6-A nrPDB Length = 391 Score = 79.0 bits (193), Expect = 3e-15, Method: Compositional matrix adjust. Identities = 63/253 (24%), Positives = 120/253 (47%), Gaps = 31/253 (12%) Query: 103 ALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQL 162 A+ L D+++I EP + + + + R + +S P+Q E G N+ + Sbjct: 102 AISLLINELTKANDKIMIQEPVYSPFNSV-VKNNNRELIIS----PLQKLENG---NYIM 153 Query: 163 DPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQQHDVVCITDEVYQWMVYD 222 D ++ K K +L P+NP+G+V++++EL+ + +C +H+V I+DE++ ++ Sbjct: 154 DYEDIENKIKD-VKLFILCNPHNPVGRVWTKDELKKLGDICLKHNVKIISDEIHSDIILK 212 Query: 223 GHQHISIASLPGMWER-TLTIGSAGKTFSATGWKVGWVLGPDHIMKHLR-------TVHQ 274 H+HI +AS+ +E+ T+T + KTF+ G + +V+ PD L + + Sbjct: 213 KHKHIPMASISKEFEKNTITCMAPTKTFNIAGLQSSYVVLPDEKDYKLLDDAFTRIDIKR 272 Query: 275 NSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFPQAMQRCRDHMIRSLQSV--GLKPI 332 N+ F S A S+ + S+ F + ++ D I+ + LK Sbjct: 273 NNCF-----SLVATEASYNNGE-------SWLESFLEYLESNIDFAIKYINENMPKLKVR 320 Query: 333 IPQGSYFLITDIS 345 P+G+Y L D S Sbjct: 321 KPEGTYLLWVDFS 333 >1IAY-A nrPDB Length = 428 Score = 78.6 bits (192), Expect = 4e-15, Method: Compositional matrix adjust. Identities = 87/370 (23%), Positives = 149/370 (40%), Gaps = 49/370 (13%) Query: 68 GYPPLTKILASFFGELLGQEI--DPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFF 125 G P K +A F + G + DP R V++ G GA T L D GD ++ P++ Sbjct: 84 GLPEFRKAIAKFMEKTRGGRVRFDPER-VVMAGGATGANETIIFCLADPGDAFLVPSPYY 142 Query: 126 DCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQL------DPMELAGKFTSRTKALV 179 + G V L P + SS+N+++ + E A K + K L+ Sbjct: 143 PAFNRDLRWRTG----VQLIPIHCE-----SSNNFKITSKAVKEAYENAQKSNIKVKGLI 193 Query: 180 LNTPNNPLGKVFSREELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERT 239 L P+NPLG ++ L+ V S QH++ + DE+Y V+D Q +SIA + E T Sbjct: 194 LTNPSNPLGTTLDKDTLKSVLSFTNQHNIHLVCDEIYAATVFDTPQFVSIAEILDEQEMT 253 Query: 240 LT-------IGSAGKTFSATGWKVGWVLG-PDHIMKHLRTVHQNSVFHCPTQSQAAVAES 291 + S K G++VG + D ++ R + +S TQ+Q +A Sbjct: 254 YCNKDLVHIVYSLSKDMGLPGFRVGIIYSFNDDVVNCARKM--SSFGLVSTQTQYFLAAM 311 Query: 292 FEREQLLFRQPSSYFVQFPQAMQRCRDHMIRSLQSVGLKPIIPQGSYFLITDISDFKRKM 351 E+ + ++ + + + H L+ VG+K + F D+ R Sbjct: 312 LSDEKFV----DNFLRESAMRLGKRHKHFTNGLEVVGIKCLKNNAGLFCWMDLRPLLR-- 365 Query: 352 PDLPGAVDEPYDRRFVKW--MIKNKGLVAIPVSIFYSVPHQKHFDHYIRFCFVK-DEATL 408 + +D W +I + L P S F + + R CF D+ T+ Sbjct: 366 -------ESTFDSEMSLWRVIINDVKLNVSPGSSF-----ECQEPGWFRVCFANMDDGTV 413 Query: 409 QAMDEKLRKW 418 ++R++ Sbjct: 414 DIALARIRRF 423 >2DOU-A nrPDB Length = 376 Score = 77.8 bits (190), Expect = 9e-15, Method: Compositional matrix adjust. Identities = 65/250 (26%), Positives = 106/250 (42%), Gaps = 26/250 (10%) Query: 30 VVNLGQGFPDFPPPDFAVEAFQHAVSGDFMLNQYTKTFGYP------PLTKILASFFGEL 83 +++L G D PPP+ ++A A LN T T+GY P + A ++ Sbjct: 27 LIDLSIGSTDLPPPEAPLKALAEA------LNDPT-TYGYCLKSCTLPFLEEAARWYEGR 79 Query: 84 LGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVS 143 G +DP R L +G L AL + D +++ E + Y +A R + Sbjct: 80 YGVGLDPRREALALIGSQEGLAHLLLALTEPEDLLLLPEVAYPSYFGAARVASLRTFLIP 139 Query: 144 LKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASLC 203 L+ + + + W+ K L+LN PNNP G V E L Sbjct: 140 LREDGLADLKAVPEGVWR------------EAKVLLLNYPNNPTGAVADWGYFEEALGLA 187 Query: 204 QQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTIGSAGKTFSATGWKVGWVLGPD 263 ++H + I D Y VY+G +A LPG ER + + S K+++ G+++G+ LG + Sbjct: 188 RKHGLWLIHDNPYVDQVYEGEAPSPLA-LPGAKERVVELFSLSKSYNLAGFRLGFALGSE 246 Query: 264 HIMKHLRTVH 273 + L V Sbjct: 247 EALARLERVK 256 >3L8A-A nrPDB Length = 421 Score = 77.4 bits (189), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 65/267 (24%), Positives = 128/267 (47%), Gaps = 21/267 (7%) Query: 93 NVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNG 152 ++L G A+ A QA ++GD V+I P + + + R V SL+ I NG Sbjct: 121 DILFIDGVVPAISIALQAFSEKGDAVLINSPVYYPFARTIRLNDHRLVENSLQ---IING 177 Query: 153 ELGSSSNWQLDPMELAGKFT-SRTKALVLNTPNNPLGKVFSREELELVASLCQQHDVVCI 211 +++D +L + K +L +P+NP G+V+ ++L +A LC++H V+ + Sbjct: 178 R------FEIDFEQLEKDIIDNNVKIYLLCSPHNPGGRVWDNDDLIKIAELCKKHGVILV 231 Query: 212 TDEVYQWMVYDGHQHISIASLPGMWER-TLTIGSAGKTFSATGWKVGWVLGPDHIMKHLR 270 +DE++Q + G+ H S+ +L ++ T+ + SA KTF+ G K + + + ++ Sbjct: 232 SDEIHQDLALFGNTHHSLNTLDASYKDFTIILSSATKTFNIAGTKNSFAIIQNESLRRKF 291 Query: 271 TVHQ--NSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFPQAMQRCRDHMIRSLQS-V 327 Q N+ PT A +F+ + +P + + ++ +I+ L++ Sbjct: 292 QYRQLANNQHEVPTVGMIATQAAFQ-----YGKP--WLEELKTVIEGNIKLVIKELEAKT 344 Query: 328 GLKPIIPQGSYFLITDISDFKRKMPDL 354 +K + P+G+Y + D S + P L Sbjct: 345 KIKVMEPEGTYLVWLDFSAYAIAQPQL 371 >3JTX-A nrPDB Length = 396 Score = 73.2 bits (178), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 93/401 (23%), Positives = 165/401 (41%), Gaps = 54/401 (13%) Query: 29 DVVNLGQGFPDFPPPDFAVEAFQHAVSGDFMLNQYTKTFGYPPLTKILASFFGELL-GQE 87 + V L G P P P +A ++ L +Y T G P L + A++ G Sbjct: 31 EAVPLHIGEPKHPTPKVITDALTASLH---ELEKYPLTAGLPELRQACANWLKRRYDGLT 87 Query: 88 IDPLRNVLVTVGGYGALFTAFQAL---VDEGDEVIII--EPFFDCYEPMTMMAGGRPVFV 142 +D +L +G ALF+ Q + V +G + I+ PF+ YE T++ GG F Sbjct: 88 VDADNEILPVLGSREALFSFVQTVLNPVSDGIKPAIVSPNPFYQIYEGATLLGGGEIHFA 147 Query: 143 SLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASL 202 + P P N +W+ ++ + RTK + + +PNNP G V + + V L Sbjct: 148 NC-PAPSFN------PDWR----SISEEVWKRTKLVFVCSPNNPSGSVLDLDGWKEVFDL 196 Query: 203 CQQHDVVCITDEVYQWMVYDGHQHI----SIASLPGMWERTLTIGSAGKTFSATGWKVGW 258 ++ + +DE Y + +DG++ + + A L ++ L S K + G + G+ Sbjct: 197 QDKYGFIIASDECYSEIYFDGNKPLGCLQAAAQLGRSRQKLLMFTSLSKRSNVPGLRSGF 256 Query: 259 VLGPDHIMKHL---RTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFPQAMQR 315 V G ++K+ RT H S P Q +A++A +++ EQ + Y +F Sbjct: 257 VAGDAELLKNFLLYRTYH-GSAMSIPVQ-RASIA-AWDDEQHVIDNRRLYQEKF------ 307 Query: 316 CRDHMIRSLQSVGLKPIIPQGSYFLITDISDFKRKMPDLPGAVDEPYDRRFVKWMIKNKG 375 + +I LQ V +P S+++ + D D F + + + Sbjct: 308 --ERVIPILQQV-FDVKLPDASFYIWLKVPDGD--------------DLAFARNLWQKAA 350 Query: 376 LVAIPVSIFYSVPHQKH-FDHYIRFCFVKDEATLQAMDEKL 415 + +P Q + + Y+R V D AT E + Sbjct: 351 IQVLPGRFLARDTEQGNPGEGYVRIALVADVATCVKAAEDI 391 >2O1B-A nrPDB Length = 404 Score = 72.8 bits (177), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 62/274 (22%), Positives = 117/274 (42%), Gaps = 21/274 (7%) Query: 30 VVNLGQGFPDFPPPDFAVEAFQHAVSGDFMLNQYTKTF-GYPPLTKILASFFGELLGQEI 88 ++N+ G PD P P ++ FQ A++ NQ F G + + F+ + Sbjct: 49 LINMAVGIPDGPTPQGIIDHFQKALT--IPENQKYGAFHGKEAFKQAIVDFYQRQYNVTL 106 Query: 89 DPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPGP 148 D V + G L +++ GD V++ +P + Y ++A G+PV ++L+P Sbjct: 107 DKEDEVCILYGTKNGLVAVPTCVINPGDYVLLPDPGYTDYLAGVLLADGKPVPLNLEP-- 164 Query: 149 IQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQQHDV 208 ++ D ++ + +TK + L PNNP G ++E + + + D Sbjct: 165 ---------PHYLPDWSKVDSQIIDKTKLIYLTYPNNPTGSTATKEVFDEAIAKFKGTDT 215 Query: 209 VCITDEVYQWMVYDGHQHISIASLPGMWERTLTIGSAGKTFSATGWKVGWVLGPDHIMKH 268 + D Y +D +AS G + + I S K ++ +G++VG+ +G +++ Sbjct: 216 KIVHDFAYGAFGFDAKNPSILASENGK-DVAIEIYSLSKGYNMSGFRVGFAVGNKDMIQA 274 Query: 269 LRT--VHQNSVFHCPTQSQAAVA----ESFEREQ 296 L+ H N+ Q A A + F EQ Sbjct: 275 LKKYQTHTNAGMFGALQDAAIYALNHYDDFLEEQ 308 >1M4N-A nrPDB Length = 435 Score = 70.5 bits (171), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 65/299 (21%), Positives = 123/299 (41%), Gaps = 32/299 (10%) Query: 68 GYPPLTKILASFFGELLGQEI--DPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFF 125 G P K + F E+ G ++ DP ++++T G A T L D G+ V+I P++ Sbjct: 87 GLPAFKKAMVDFMAEIRGNKVTFDP-NHLVLTAGATSANETFIFCLADPGEAVLIPTPYY 145 Query: 126 DCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMEL------AGKFTSRTKALV 179 ++ G + PI SS+ +Q+ L A K R K ++ Sbjct: 146 PGFDRDLKWRTGVEIV------PIH---CTSSNGFQITETALEEAYQEAEKRNLRVKGVL 196 Query: 180 LNTPNNPLGKVFSREELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASL------- 232 + P+NPLG +R EL L+ S + + I+DE+Y + IS+ + Sbjct: 197 VTNPSNPLGTTMTRNELYLLLSFVEDKGIHLISDEIYSGTAFSSPSFISVMEVLKDRNCD 256 Query: 233 --PGMWERTLTIGSAGKTFSATGWKVGWVLGPDHIMKHLRTVHQNSVFHCPTQSQAAVAE 290 +W+R + S K G++VG + D ++ T +S +Q+Q ++ Sbjct: 257 ENSEVWQRVHVVYSLSKDLGLPGFRVGAIYSNDDMVVAAAT-KMSSFGLVSSQTQHLLSA 315 Query: 291 SFEREQLLFRQPSSYFVQFPQAMQRCRDHMIRSLQSVGLKPIIPQGSYFLITDISDFKR 349 ++L +Y + + +++ + ++ LQ G+ + F D+ R Sbjct: 316 MLSDKKL----TKNYIAENHKRLKQRQKKLVSGLQKSGISCLNGNAGLFCWVDMRHLLR 370 >1X0M-A nrPDB Length = 403 Score = 69.3 bits (168), Expect = 3e-12, Method: Compositional matrix adjust. Identities = 91/422 (21%), Positives = 170/422 (40%), Gaps = 62/422 (14%) Query: 20 EFVKLASEHDVVNLGQGFPD---FPPP---DFAVEAFQHAVSGDFMLNQYTKTFGYPPLT 73 E +KL D+++L G P+ FP D VE + QY T G+ PL Sbjct: 23 ELLKLVETSDIISLAGGLPNPKTFPKEIIRDILVEIMEKYADKAL---QYGTTKGFTPLR 79 Query: 74 KILASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPF-------FD 126 + L + G+ G D ++++T G AL + ++ GD V++ P F+ Sbjct: 80 ETLMKWLGKRYGISQD--NDIMITSGSQQALDLIGRVFLNPGDIVVVEAPTYLAALQAFN 137 Query: 127 CYEPMTMMAGGRPVFVSLKPGPIQN-GELGSSSNWQLDPMELAGKFTSRTKALVLNTPN- 184 YEP + P+ + G +L ++ GK +V P Sbjct: 138 FYEPQYIQI------------PLDDEGMKVEILEEKLKELKSQGKKVK----VVYTVPTF 181 Query: 185 -NPLGKVFSREELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTIG 243 NP G + + + + L ++D + + D+ Y + Y G+ I +L R + +G Sbjct: 182 QNPAGVTMNEDRRKYLLELASEYDFIVVEDDPYGELRYSGNPEKKIKALDNEG-RVIYLG 240 Query: 244 SAGKTFSATGWKVGWVLGPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPS 303 + K A G+++GW++G I++ + Q++ C VA + L Sbjct: 241 TFSKIL-APGFRIGWMVGDPGIIRKMEIAKQSTDL-CTNVFGQVVAWRYVDGGYL----E 294 Query: 304 SYFVQFPQAMQRCRDHMIRSLQSV---GLKPIIPQGSYFLITDISDFKRKMPDLPGAVDE 360 + + + + RD M+ +L+ G+K P+G F+ LP +D Sbjct: 295 KHIPEIRKFYKPRRDAMLEALEEFMPEGVKWTKPEGGMFIWV----------TLPDGID- 343 Query: 361 PYDRRFVKWMIKNKGLVAIPVSIFYSVPHQKHFDHYIRFCFVKDEATLQAMDEKLRKWKV 420 ++ ++ IK KG+ +P FY+ K+ + F +V ++ ++ + K Sbjct: 344 --SKKMLERAIK-KGVAYVPGEAFYAHRDVKN-TMRLNFTYVDEDKIMEGIKRLAETIKE 399 Query: 421 EL 422 EL Sbjct: 400 EL 401 >3AV7-A nrPDB Length = 448 Score = 69.3 bits (168), Expect = 3e-12, Method: Compositional matrix adjust. Identities = 91/422 (21%), Positives = 170/422 (40%), Gaps = 62/422 (14%) Query: 20 EFVKLASEHDVVNLGQGFPD---FPPP---DFAVEAFQHAVSGDFMLNQYTKTFGYPPLT 73 E +KL D+++L G P+ FP D VE + QY T G+ PL Sbjct: 68 ELLKLVETSDIISLAGGLPNPKTFPKEIIRDILVEIMEKYADKAL---QYGTTKGFTPLR 124 Query: 74 KILASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPF-------FD 126 + L + G+ G D ++++T G AL + ++ GD V++ P F+ Sbjct: 125 ETLMKWLGKRYGISQD--NDIMITSGSQQALDLIGRVFLNPGDIVVVEAPTYLAALQAFN 182 Query: 127 CYEPMTMMAGGRPVFVSLKPGPIQN-GELGSSSNWQLDPMELAGKFTSRTKALVLNTPN- 184 YEP + P+ + G +L ++ GK +V P Sbjct: 183 FYEPQYIQI------------PLDDEGMKVEILEEKLKELKSQGKKVK----VVYTVPTF 226 Query: 185 -NPLGKVFSREELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTIG 243 NP G + + + + L ++D + + D+ Y + Y G+ I +L R + +G Sbjct: 227 QNPAGVTMNEDRRKYLLELASEYDFIVVEDDPYGELRYSGNPEKKIKALDNEG-RVIYLG 285 Query: 244 SAGKTFSATGWKVGWVLGPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPS 303 + K A G+++GW++G I++ + Q++ C VA + L Sbjct: 286 TFSKIL-APGFRIGWMVGDPGIIRKMEIAKQSTDL-CTNVFGQVVAWRYVDGGYL----E 339 Query: 304 SYFVQFPQAMQRCRDHMIRSLQSV---GLKPIIPQGSYFLITDISDFKRKMPDLPGAVDE 360 + + + + RD M+ +L+ G+K P+G F+ LP +D Sbjct: 340 KHIPEIRKFYKPRRDAMLEALEEFMPEGVKWTKPEGGMFIWV----------TLPDGID- 388 Query: 361 PYDRRFVKWMIKNKGLVAIPVSIFYSVPHQKHFDHYIRFCFVKDEATLQAMDEKLRKWKV 420 ++ ++ IK KG+ +P FY+ K+ + F +V ++ ++ + K Sbjct: 389 --SKKMLERAIK-KGVAYVPGEAFYAHRDVKN-TMRLNFTYVDEDKIMEGIKRLAETIKE 444 Query: 421 EL 422 EL Sbjct: 445 EL 446 >3OP7-A nrPDB Length = 375 Score = 64.3 bits (155), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 74/329 (22%), Positives = 134/329 (40%), Gaps = 49/329 (14%) Query: 94 VLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGE 153 +L T G GA +L++ GD VI + P Y+ + + V L +NG Sbjct: 84 ILQTNGATGANLLVLYSLIEPGDHVISLYP---TYQQLYDIPKSLGAEVDLWQIEEENG- 139 Query: 154 LGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQQHDVVCITD 213 W D +L TK + +N NNP G V R LE + + + ++D Sbjct: 140 ------WLPDLEKLRQLIRPTTKMICINNANNPTGAVMDRTYLEELVEIASEVGAYILSD 193 Query: 214 EVYQWMVYDGHQHISIASLPGMWERTLTIGSAGKTFSATGWKVGWVLGPDHIMKHLRTVH 273 EVY+ + + S+ ++++ + + S KT+S G ++GWV + LR + Sbjct: 194 EVYR-----SFSELDVPSIIEVYDKGIAVNSLSKTYSLPGIRIGWVAANHQVTDILRD-Y 247 Query: 274 QNSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFPQAMQRCRDHMIRSL----QSVGL 329 ++ C VA+ + + ++R R + +L Q + Sbjct: 248 RDYTMICAGVFDDLVAQLA-------------LAHYQEILERNRHILEENLAILDQWIEE 294 Query: 330 KPIIPQGSYFLITDISDFKRKMPDLPGAVDEPYDRRFVKWMIKNKGLVAIPVSIFYSVPH 389 +P++ SY +S K+ AVD P + F +++ G++ +P + F Sbjct: 295 EPLV---SYIRPAVVSTSFVKI-----AVDMPME-DFCLQLLQEHGVLLVPGNRF----- 340 Query: 390 QKHFDHYIRFCFVKDEATLQAMDEKLRKW 418 D Y+R F ++ TL EKL ++ Sbjct: 341 --ERDGYVRLGFACEQETLIKGLEKLSQF 367 >1VP4-A nrPDB Length = 425 Score = 64.3 bits (155), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 72/335 (21%), Positives = 144/335 (42%), Gaps = 31/335 (9%) Query: 20 EFVKLASEHDVVNLGQGFPD---FPPPDFAVEAFQHAVSGDFMLN-QYTKTFGYPPLT-- 73 E +K A++ D ++ G G PD FP + A E + + ++ QY+ T G P L Sbjct: 35 EILKFAADKDAISFGGGVPDPETFPRKELA-EIAKEIIEKEYHYTLQYSTTEGDPVLKQQ 93 Query: 74 --KILASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPM 131 K+L +G + G + D N++ TVG AL + +D+ ++ +P + + Sbjct: 94 ILKLLERMYG-ITGLDED---NLIFTVGSQQALDLIGKLFLDDESYCVLDDPAY-----L 144 Query: 132 TMMAGGRPVFVSLKPGPIQNGELGSSS-NWQLDPMELAGKFTSRTKALVLNTPNNPLGKV 190 + R + P+++ + + +L + GK V++ +NP G Sbjct: 145 GAINAFRQYLANFVVVPLEDDGMDLNVLERKLSEFDKNGKIKQVKFIYVVSNFHNPAGVT 204 Query: 191 FSREELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTIGSAGKTFS 250 S E+ + + + +++D+ + D+ Y + Y+G I + G ER + + + K Sbjct: 205 TSLEKRKALVEIAEKYDLFIVEDDPYGALRYEGETVDPIFKIGGP-ERVVLLNTFSKVL- 262 Query: 251 ATGWKVGWVLGPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFP 310 A G ++G V G ++ + Q++ P + A ER LL + + Sbjct: 263 APGLRIGMVAGSKEFIRKIVQAKQSADLCSPAITHRLAARYLERYDLLEQLKPTI----- 317 Query: 311 QAMQRCRDHMIRSLQSV-----GLKPIIPQGSYFL 340 + +R R M+ +L+ G+K + +G F+ Sbjct: 318 ELYRRKRTVMLNALEEYFSDIPGVKWVKSEGGLFI 352 >5Z0Q-C nrPDB Length = 389 Score = 63.9 bits (154), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 61/247 (24%), Positives = 105/247 (42%), Gaps = 24/247 (9%) Query: 23 KLASEHDVVNLGQGFPDFPPPDFAVEAFQHAVSGDFMLNQYTKTFGYPPLTKILASFFGE 82 K ++ D++ L DF D ++A Q V FGY ++ LA E Sbjct: 28 KKYADRDILPLWIADTDFRAADCIIDALQQRVQ--------QGVFGYGVTSEALAEVAIE 79 Query: 83 LL----GQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGR 138 + G +I P V + G + A +A + + P + + +AG + Sbjct: 80 RMESRFGWKIQPEWLVFLP-GVVTGINIAVRAFTEAHQSTVSATPIYPPFFLAPKLAGRQ 138 Query: 139 PVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELEL 198 + +L+ W LD + + K L+L P+NP G V+ R+ELE Sbjct: 139 HLSAALRL---------EQQRWVLDLDSHEDRMSGNEKLLLLCNPHNPGGTVYRRKELEA 189 Query: 199 VASLCQQHDVVCITDEVYQWMVYD-GHQHISIASLP-GMWERTLTIGSAGKTFSATGWKV 256 Q+HD++ +DE++ +V + G QHI ASL +R++T+ S K+F+ G Sbjct: 190 QLRFAQRHDLLVCSDEIHCDLVLEPGVQHIPFASLSDDAAQRSITLMSPSKSFNIAGLGA 249 Query: 257 GWVLGPD 263 + P+ Sbjct: 250 SLAVIPN 256 >3EZS-A nrPDB Length = 376 Score = 60.8 bits (146), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 62/248 (25%), Positives = 101/248 (40%), Gaps = 25/248 (10%) Query: 31 VNLGQGFPDFPPPDFAVEAFQHAVSGDFMLNQYTKTFGYPPLTKILASFFGELLGQEIDP 90 ++LG G P F P F +A ++ LN Y K+ L FF E+ Sbjct: 26 LDLGIGEPQFETPKFIQDALKNHTHS---LNIYPKSAFEESLRAAQRGFFKRRFKIELKE 82 Query: 91 LRNVLVTVGGYGALFT--AFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPGP 148 ++ T+G LF +F + + PF+ YE + + L P Sbjct: 83 -NELISTLGSREVLFNFPSFVLFDYQNPTIAYPNPFYQIYEGAAKFIKAKSL---LMPLT 138 Query: 149 IQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQQHDV 208 +N S + +L ++L ++LN+PNNP G+ S EEL L +HD Sbjct: 139 KENDFTPSLNEKELQEVDL----------VILNSPNNPTGRTLSLEELISWVKLALKHDF 188 Query: 209 VCITDEVYQWMVYDGHQHISIAS---LPG--MWERTLTIGSAGKTFSATGWKVGWVLGPD 263 + I DE Y +Y+ S+ L G ++ L I S K SA G + G++ G Sbjct: 189 ILINDECYS-EIYENTPPPSLLEACMLAGNEAFKNVLVIHSLSKRSSAPGLRSGFIAGDS 247 Query: 264 HIMKHLRT 271 +++ + Sbjct: 248 RLLEKYKA 255 >4FL0-A nrPDB Length = 456 Score = 60.1 bits (144), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 62/264 (23%), Positives = 108/264 (40%), Gaps = 16/264 (6%) Query: 4 QLQARRLDGIDYNPWVEFVKLASEHDVVNLGQGFPDFPPPDFAVEAFQHAVSGDFMLNQY 63 ++ R L+ I+ +P V+ +++LG G P P+ + G + Y Sbjct: 55 EINRRELEHIEKHPNVQ---------LISLGTGDTTEPIPEQITSHMSNFAHGLSTVEGY 105 Query: 64 TKTFGYPPLTKILASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEP 123 + +G K L E +++ N + G + + Q L+ + + +P Sbjct: 106 -RGYGLEQGNKTLRKAIAETFYRDLHVKSNEVFVSDGAQSDISRLQLLLGSNVTIAVQDP 164 Query: 124 FFDCYEPMTMMAGGRPVFVSLKPGPIQNG-ELGSSSNWQLDPMELAGKFTSRTKALVLNT 182 F Y +++ G F K QN + N P +LA T RT + + Sbjct: 165 TFPAYIDSSVIIGQTGHFHE-KTKKYQNVVYMPCGPNNSFFP-DLA--MTPRTDVIFFCS 220 Query: 183 PNNPLGKVFSREELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTI 242 PNNP G V SR++L + + + + I D Y + DG SI +PG E + + Sbjct: 221 PNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPR-SIYEIPGAREVAIEV 279 Query: 243 GSAGKTFSATGWKVGWVLGPDHIM 266 S K TG ++GW + PD ++ Sbjct: 280 SSFSKFAGFTGVRLGWSIIPDELL 303 >4M2J-A nrPDB Length = 406 Score = 59.7 bits (143), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 48/175 (27%), Positives = 76/175 (43%), Gaps = 15/175 (8%) Query: 93 NVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPG-PIQN 151 VLVT G A+ AL+ GD V++ E + AG V++ PG +++ Sbjct: 104 RVLVTHGSSEAIALTLNALLHRGDRVVVQEGIYHSLGHYPRAAG---CDVAVLPGRAVRD 160 Query: 152 GELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQQHDVVCI 211 GE+ DP LAG T T A+++N P+NP G S + L + V + Sbjct: 161 GEI--------DPDVLAGLVTPGTAAVIVNFPHNPTGVTLSPQGLRALKERTAATGAVLV 212 Query: 212 TDEVYQWMVYDGHQHISIASLPGMWERTLTIGSAGKTFSATGWKVGWVLGPDHIM 266 D + H+ +A T++ G+ KTF G +VGW + P ++ Sbjct: 213 WDAATAEIA---HRWEVLADPGADGGDTVSYGTLSKTFGLPGLRVGWAVAPKELL 264 >1C7O-A nrPDB Length = 399 Score = 59.3 bits (142), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 41/165 (24%), Positives = 82/165 (49%), Gaps = 17/165 (10%) Query: 94 VLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPGP---IQ 150 ++ T G A+F A + GD VIII P + P F+++K I+ Sbjct: 92 IINTAGVVPAVFNAVREFTKPGDGVIIITPVY------------YPFFMAIKNQERKIIE 139 Query: 151 NGELGSSSNWQLDPMELAGKFTSRT-KALVLNTPNNPLGKVFSREELELVASLCQQHDVV 209 L + +D +L + KAL+ +P+NP+G+V+ ++EL+ + + + D++ Sbjct: 140 CELLEKDGYYTIDFQKLEKLSKDKNNKALLFCSPHNPVGRVWKKDELQKIKDIVLKSDLM 199 Query: 210 CITDEVYQWMVYDGHQHISIASL-PGMWERTLTIGSAGKTFSATG 253 +DE++ ++ G++H S+ + ++T+T + KTF+ G Sbjct: 200 LWSDEIHFDLIMPGYEHTVFQSIDEQLADKTITFTAPSKTFNIAG 244 >3F6T-A nrPDB Length = 533 Score = 57.8 bits (138), Expect = 9e-09, Method: Compositional matrix adjust. Identities = 51/198 (25%), Positives = 85/198 (42%), Gaps = 29/198 (14%) Query: 74 KILASFFGEL------LGQEIDPLRNVLVTVGGYGALFTAFQALVD-----EGDEVIIIE 122 KI+ F EL L ++ D + T GG A+ AF +L + +GD++ I E Sbjct: 145 KIINYFLQELSYKDANLAEQTD----LFPTEGGTAAIVYAFHSLAENHLLKKGDKIAINE 200 Query: 123 PFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNT 182 P F Y + + V V L ++W+++P E+ KAL++ Sbjct: 201 PIFTPYLRIPELKDYELVEVDLHSY--------EKNDWEIEPNEIEKLKDPSIKALIVVN 252 Query: 183 PNNPLGKVFSREELELVASLCQQH-DVVCITDEVYQWMVYDGHQHISIASLPGMWERTLT 241 P NP K F L + +++ ++ I+DEVY V + S+ T+ Sbjct: 253 PTNPTSKEFDTNALNAIKQAVEKNPKLMIISDEVYGAFVPNFKSIYSVVPY-----NTML 307 Query: 242 IGSAGKTFSATGWKVGWV 259 + S K F TGW++G + Sbjct: 308 VYSYSKLFGCTGWRLGVI 325 >1WST-A nrPDB Length = 417 Score = 55.8 bits (133), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 86/405 (21%), Positives = 159/405 (39%), Gaps = 49/405 (12%) Query: 20 EFVKLASEHDVVNLGQGFPDFPPPDFAVEAFQHAV------SGDFMLNQYTKTFGYPPLT 73 E +KL DV++L G P P F VE + D L QY T G+ PL Sbjct: 33 ELLKLVETSDVISLAGGLP--APETFPVETIKKIAVEVLEEHADKAL-QYGTTKGFTPLR 89 Query: 74 KILASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTM 133 LA + + + + ++ G AL + ++ GD +++ P + + Sbjct: 90 LALARWMEKRYDIPMSKV-EIMTVAGSQQALDLIGRVFLNPGDPIVVEAPTYLA--AIQA 146 Query: 134 MAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKAL-VLNTPNNPLGKVFS 192 P F+S+ P+ + G + + +E K R K + ++T NP G S Sbjct: 147 FKYYDPEFISI---PLDDK--GMRVDLLEEKLEELRKQGKRVKIVYTVSTFQNPAGVTMS 201 Query: 193 REELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTIGSAGKTFSAT 252 + + + L ++D + + D Y + Y G I + R + +G+ K A Sbjct: 202 VDRRKKLLELANEYDFLIVEDGPYSELRYSGEPTPPIKHFDD-YGRVIYLGTFSKIL-AP 259 Query: 253 GWKVGWVLGPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFPQA 312 G+++GWV H+++ + Q S+ C A+A + L + + + Sbjct: 260 GFRIGWVAAHPHLIRKMEIAKQ-SIDLCTNTFGQAIAWKYVENGYL----DEHIPKIIEF 314 Query: 313 MQRCRDHMIRSLQSV---GLKPIIPQGSYFLITDISDFKRKMPDLPGAVDEPYDRRFVKW 369 + RD M+ +L+ G++ P+G F+ LP +D K Sbjct: 315 YKPRRDAMLEALEEYMPEGVEWTKPEGGMFVRV----------TLPEGID-------TKL 357 Query: 370 MIKN---KGLVAIPVSIFYSVPHQKHFDHYIRFCFVKDEATLQAM 411 M++ KG+ +P F+ V K + F +V +E + + Sbjct: 358 MMERAVAKGVAYVPGEAFF-VHRDKKNTMRLNFTYVPEETIREGV 401 >2ZY3-A nrPDB Length = 546 Score = 55.1 bits (131), Expect = 6e-08, Method: Compositional matrix adjust. Identities = 53/193 (27%), Positives = 77/193 (39%), Gaps = 31/193 (16%) Query: 93 NVLVTVGGYGALFTAFQAL-----VDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPG 147 N+ GG A+ F++L + GD+V I P F Y + +A V++ Sbjct: 167 NLFAVEGGTAAMAYIFESLKLNGLLKAGDKVAIGMPVFTPYIEIPELAQYALEEVAINAD 226 Query: 148 PIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQQH- 206 P S NWQ EL K P+NP + LE V ++ +H Sbjct: 227 P--------SLNWQYPDSELDKLKDPAIKIFFCVNPSNPPSVKMDQRSLERVRNIVAEHR 278 Query: 207 -DVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTIGSAGKTFSATGWKVGWVLGPDHI 265 D++ +TD+VY D +I E TL + S K F ATGW++G V Sbjct: 279 PDLMILTDDVYGTFADDFQSLFAICP-----ENTLLVYSFSKYFGATGWRLGVV------ 327 Query: 266 MKHLRTVHQNSVF 278 HQ +VF Sbjct: 328 -----AAHQQNVF 335 >1D2F-A nrPDB Length = 390 Score = 53.9 bits (128), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 31/76 (40%), Positives = 50/76 (65%), Gaps = 4/76 (5%) Query: 176 KALVLNTPNNPLGKVFSREELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLP-G 234 K ++L +P NP GKV++ +ELE++A LC++H V I+DE++ MV+ HI +++ G Sbjct: 164 KIMLLCSPQNPTGKVWTCDELEIMADLCERHGVRVISDEIHMDMVWGEQPHIPWSNVARG 223 Query: 235 MWERTLTIGSAGKTFS 250 W LT GS K+F+ Sbjct: 224 DWA-LLTSGS--KSFN 236 >3DZZ-A nrPDB Length = 391 Score = 51.2 bits (121), Expect = 8e-07, Method: Compositional matrix adjust. Identities = 27/103 (26%), Positives = 55/103 (53%), Gaps = 10/103 (9%) Query: 115 GDEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKF-TS 173 GD++++ EP ++ + + G R + L + +S + ++ +L K T Sbjct: 109 GDQILVQEPVYNMFYSVIEGNGRRVISSDL---------IYENSKYSVNWADLEEKLATP 159 Query: 174 RTKALVLNTPNNPLGKVFSREELELVASLCQQHDVVCITDEVY 216 + +V P+NP+G +S EE++ +A LC +H V+ I+DE++ Sbjct: 160 SVRMMVFCNPHNPIGYAWSEEEVKRIAELCAKHQVLLISDEIH 202 >3FDD-A nrPDB Length = 533 Score = 51.2 bits (121), Expect = 9e-07, Method: Compositional matrix adjust. Identities = 53/207 (25%), Positives = 82/207 (39%), Gaps = 26/207 (12%) Query: 93 NVLVTVGGYGALFTAFQA-----LVDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPG 147 N+ GG A+ F++ L+ GD+V I P F Y + +A V++ Sbjct: 167 NLFAVEGGTAAMAYIFESMKVNGLLKAGDKVAIGMPVFTPYIEIPELAQYALEEVAINAD 226 Query: 148 PIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQQH- 206 P + NWQ EL K P+NP LE V + +H Sbjct: 227 P--------ALNWQYPDSELDKLKDPAIKIFFCVNPSNPPSVKMDERSLERVRKIVAEHR 278 Query: 207 -DVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTIGSAGKTFSATGWKVGWVLGPDHI 265 D++ +TD+VY DG Q + A P TL + S K F ATGW++G V Sbjct: 279 PDLMILTDDVYGTFA-DGFQSL-FAICPA---NTLLVYSFSKYFGATGWRLGVVAA---- 329 Query: 266 MKHLRTVHQNSVFHCPTQSQAAVAESF 292 H + ++ P + A+ + + Sbjct: 330 --HKENIFDLALGRLPESEKTALDDRY 354 >3IF2-A nrPDB Length = 444 Score = 50.8 bits (120), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 54/247 (21%), Positives = 102/247 (41%), Gaps = 38/247 (15%) Query: 174 RTKALVLNTPNNPLGKVFSREELELVASLCQQHDVVCITDEVYQW----MVY-DGHQHIS 228 R A+ + P NP G V + EE+ +A + +++D+ I D Y ++Y D H + Sbjct: 206 RIGAICCSRPTNPTGNVLTDEEMAHLAEIAKRYDIPLIIDNAYGMPFPNIIYSDAHLN-- 263 Query: 229 IASLPGMWERTLTIGSAGKTFSATGWKVGWVLGPDHIMKHLRTVHQNSVFH-CPTQSQAA 287 W+ + + G + G ++ +++ + + N+V + PT+ AA Sbjct: 264 -------WDNNTILCFSLSKIGLPGMRTGIIVADAKVIEAVSAM--NAVVNLAPTRFGAA 314 Query: 288 VAESFEREQLLFRQPSSYFVQFPQAMQRCRDHMIRSLQSVGLKPII---PQGSYFLITDI 344 +A + + + F Q +++ Q++G P++ P+G+ FL Sbjct: 315 IATPLVANDRIKQLSDNEIKPFYQKQATLAVKLLK--QALGDYPLMIHKPEGAIFLWL-- 370 Query: 345 SDFKRKMPDLPGAVDEPYDRRFVKWMIKNKGLVAIPVSIFY---SVPHQKHFDHYIRFCF 401 DLP + + Y+R +K KG + +P F+ V +H IR Sbjct: 371 -----WFKDLPISTLDLYER------LKAKGTLIVPSEYFFPGVDVSDYQHAHECIRMSI 419 Query: 402 VKDEATL 408 DE TL Sbjct: 420 AADEQTL 426 >4R2N-A nrPDB Length = 367 Score = 50.4 bits (119), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 45/198 (22%), Positives = 75/198 (37%), Gaps = 16/198 (8%) Query: 76 LASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMA 135 L + LG + P +V V G Q GDEV+ F+ Y P +A Sbjct: 63 LKAALARHLGPDFAP-EHVAVGCGSVSLCQQLVQVTASVGDEVVFGWRSFELYPPQVRVA 121 Query: 136 GGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREE 195 G P+ V L ++ D + T RT+ + + PNNP V + Sbjct: 122 GAIPIQVPL-------------TDHTFDLYAMLATVTDRTRLIFVCNPNNPTSTVVGPDA 168 Query: 196 LELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTIGSAGKTFSATGWK 255 L H ++ I DE Y + DG + S+ L + + + K + G + Sbjct: 169 LARFVEAVPAHILIAI-DEAYVEYIRDGMRPDSL-GLVRAHNNVVVLRTFSKAYGLAGLR 226 Query: 256 VGWVLGPDHIMKHLRTVH 273 +G+ +G ++ L V+ Sbjct: 227 IGYAIGHPDVITALDKVY 244 >3ASB-A nrPDB Length = 400 Score = 50.1 bits (118), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 54/244 (22%), Positives = 94/244 (38%), Gaps = 26/244 (10%) Query: 27 EHDVVNLGQGFPDFPPPDFAVEAFQHAV---SGDFMLNQYTKTFGYPPLTKILASFF--G 81 +H V+NL G P EAF ++ S Y FG P L + L+ F G Sbjct: 32 QHTVINLSIGDTTQPLNASVAEAFASSIARLSSPTTCRGYGPDFGLPALRQKLSEDFYRG 91 Query: 82 ELLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPVF 141 + +EI ++ G LF + V I +P + Y + + G + + Sbjct: 92 FVDAKEI------FISDGAKVDLFRLL-SFFGPNQTVAIQDPSYPAYLDIARLTGAKEI- 143 Query: 142 VSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVAS 201 I L ++ + P + + L L +PNNP G V ++++L + Sbjct: 144 -------IALPCLQENAFFPEFPED------THIDILCLCSPNNPTGTVLNKDQLRAIVH 190 Query: 202 LCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTIGSAGKTFSATGWKVGWVLG 261 +H+++ + D Y + D SI +P + I S K G ++GW + Sbjct: 191 YAIEHEILILFDAAYSTFISDPSLPKSIFEIPDARFCAIEINSFSKPLGFAGIRLGWTVI 250 Query: 262 PDHI 265 P + Sbjct: 251 PQEL 254 >3FDB-A nrPDB Length = 377 Score = 48.5 bits (114), Expect = 6e-06, Method: Compositional matrix adjust. Identities = 41/202 (20%), Positives = 83/202 (41%), Gaps = 23/202 (11%) Query: 65 KTFGYPP----LTKILASFFGELLGQEIDP--LRNVLVTVGGYGALFTAFQALVDEGDEV 118 + FGY P L++ A F+ + G + P + + V G L+ A +V Sbjct: 52 EAFGYQPDGSLLSQATAEFYADRYGYQARPEWIFPIPDVVRG---LYIAIDHFTPAQSKV 108 Query: 119 IIIEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKAL 178 I+ P + + + +F+ G ++ ++ F + +++ Sbjct: 109 IVPTPAYPPFFHLLSATQREGIFIDATGG--------------INLHDVEKGFQAGARSI 154 Query: 179 VLNTPNNPLGKVFSREELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWER 238 +L P NPLG VF+ E L + L ++D + DE++ +V+DG ++ Sbjct: 155 LLCNPYNPLGMVFAPEWLNELCDLAHRYDARVLVDEIHAPLVFDGQHTVAAGVSDTAASV 214 Query: 239 TLTIGSAGKTFSATGWKVGWVL 260 +TI + K ++ G K ++ Sbjct: 215 CITITAPSKAWNIAGLKCAQII 236 >3EI8-A nrPDB Length = 432 Score = 47.8 bits (112), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 54/242 (22%), Positives = 96/242 (39%), Gaps = 15/242 (6%) Query: 30 VVNLGQGFPDFPPPDFAVEAFQ---HAVSGDFMLNQYTKTFGYPPLTKILASFFGELLGQ 86 V++LG G P P+ A H +S + Y G PL +A F LG Sbjct: 58 VISLGIGDTTEPIPEVITSAMAKKAHELSTIEGYSGYGAEQGAKPLRAAIAKTFYGGLGI 117 Query: 87 EIDPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVS--L 144 D +V V+ G + + Q + + + +P + Y +++ G F + Sbjct: 118 GDD---DVFVSDGAKCDI-SRLQVMFGSNVTIAVQDPSYPAYVDSSVIMGQTGQFNTDVQ 173 Query: 145 KPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQ 204 K G I+ + + D + RT + +PNNP G +RE+L + + Sbjct: 174 KYGNIEYMRCTPENGFFPDLSTVG-----RTDIIFFCSPNNPTGAAATREQLTQLVEFAK 228 Query: 205 QHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTIGSAGKTFSATGWKVGWVLGPDH 264 ++ + + D Y + D + SI +PG E + S TG ++GW + P Sbjct: 229 KNGSIIVYDSAYAMYMSDDNPR-SIFEIPGAEEVAMETASFSNYAGFTGVRLGWTVIPKK 287 Query: 265 IM 266 ++ Sbjct: 288 LL 289 >3G0T-A nrPDB Length = 437 Score = 47.4 bits (111), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 60/257 (23%), Positives = 102/257 (39%), Gaps = 23/257 (8%) Query: 14 DYNPWVEFVKLASEHDVVNLGQGFPDFPPPDFAVEA-FQHAVSGDFMLNQYTKTFGYPPL 72 D V ++ A+ + G P P P +E Q G + + Y G P L Sbjct: 30 DLVALVTNLEKATGTKFCRMEMGVPGLPAPQIGIETEIQKLREG--VASIYPNLDGLPEL 87 Query: 73 TKILASFFGELLGQEIDPLRNVLVTVGGYGALFTAF----QALVDEGDEVIIIEPFFDCY 128 K AS F +L P R + TVG F +F + + + I+P F+ Sbjct: 88 -KQEASRFAKLFVNIDIPARACVPTVGSMQGCFVSFLVANRTHKNREYGTLFIDPGFNLN 146 Query: 129 EPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLG 188 + + G + F S + G +L+ G+F S ++ + PNNP Sbjct: 147 KLQCRILGQK--FESFDLFEYR----GEKLREKLESYLQTGQFCS----IIYSNPNNPTW 196 Query: 189 KVFSREELELVASLCQQHDVVCITDEVYQWMVY-DGHQH----ISIASLPGMWERTLTIG 243 + + EEL ++ L +HDV+ I D Y M + + H + S+ + + Sbjct: 197 QCMTDEELRIIGELATKHDVIVIEDLAYFGMDFRKDYSHPGEPLYQPSVANYTDNYILAL 256 Query: 244 SAGKTFSATGWKVGWVL 260 S+ K FS G ++G ++ Sbjct: 257 SSSKAFSYAGQRIGVLM 273 >4GDY-A nrPDB Length = 439 Score = 47.0 bits (110), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 44/199 (22%), Positives = 91/199 (45%), Gaps = 4/199 (2%) Query: 93 NVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPVFV-SLKPGPIQN 151 ++ VT G L F+ +++ GD V++ EP + G + V S + G + + Sbjct: 110 DLCVTSGSQQGLCKVFEMIINPGDNVLLDEPAYSGTLQSLHPLGCNIINVASDESGIVPD 169 Query: 152 GELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQQHDVVCI 211 S W+ + + K T + V N NNP G + E + + L +++D + I Sbjct: 170 SLRDILSRWKPEDAKNPQKNTPKFLYTVPNG-NNPTGNSLTSERKKEIYELARKYDFLII 228 Query: 212 TDEVYQWMVYDGHQHISIASLPGMWERTLTIGSAGKTFSATGWKVGWVLGPDHIMKHLRT 271 D+ Y ++ ++ + + S+ + R + S K S +G ++G++ GP +++ + Sbjct: 229 EDDPYYFLQFNSGRVPTFLSM-DVDGRVIRADSFSKIIS-SGLRIGFLTGPKPLIERVIL 286 Query: 272 VHQNSVFHCPTQSQAAVAE 290 Q S H T +Q +++ Sbjct: 287 HIQVSTLHPSTFNQLMISQ 305 >3HDO-A nrPDB Length = 360 Score = 46.6 bits (109), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 61/272 (22%), Positives = 106/272 (38%), Gaps = 41/272 (15%) Query: 73 TKILASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMT 132 ++ L GEL G DP +++ G L +A EG+E+ + P + Y + Sbjct: 67 SQKLREVAGELYG--FDP-SWIIMANGSDEVLNNLIRAFAAEGEEIGYVHPSYSYYGTLA 123 Query: 133 MMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSR--TKALVLNTPNNPLGKV 190 + G R L G+ +AG F R K L TPN PLG Sbjct: 124 EVQGARVRTFGL------TGDF-----------RIAG-FPERYEGKVFFLTTPNAPLGPS 165 Query: 191 FSREELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTIGSAGKTFS 250 F E ++ +A C + + DE Y + + RTL+ K++S Sbjct: 166 FPLEYIDELARRCAG---MLVLDETYAEFAESNALELVRRHENVVVTRTLS-----KSYS 217 Query: 251 ATGWKVGWVLGPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFP 310 G ++G + ++ L + + ++ +QAA + R+Q +Y + Sbjct: 218 LAGMRIGLAIARPEVIAALDKIRDH--YNLDRLAQAACVAAL-RDQ-------AYLSECC 267 Query: 311 QAMQRCRDHMIRSLQSVGLKPIIPQGSYFLIT 342 + ++ R+ L+S+G I QG+Y T Sbjct: 268 RRIRETREWFTTELRSIGYDVIPSQGNYLFAT 299 >2ZY2-A nrPDB Length = 544 Score = 46.2 bits (108), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 73/350 (20%), Positives = 125/350 (35%), Gaps = 90/350 (25%) Query: 82 ELLGQEIDPLRNVLVTV-GGYGALFTAFQAL-----VDEGDEVIIIEPFFDCYEPMTMMA 135 E+ G + P L V GG A+ F++L + GD+V I P F Y + +A Sbjct: 154 EMAGGAVPPESVDLFAVEGGTAAMAYIFESLRISGLLKAGDKVAIGMPVFTPYIEIPELA 213 Query: 136 GGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREE 195 LK PI + WQ EL K P+NP + Sbjct: 214 Q-----YDLKEVPIHAD---PDNGWQYSDAELDKLKDPDVKIFFCVNPSNPPSVKMDQRS 265 Query: 196 LELVASLC--QQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTIGSAGKTFSATG 253 L+ V ++ Q+ D++ +TD+VY + S+ TL + S K F ATG Sbjct: 266 LDRVRAIVAEQRPDLLILTDDVYGTFADEFQSLFSVCP-----RNTLLVYSFSKYFGATG 320 Query: 254 WKVGWVLGPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFPQAM 313 W++G + H+++VF Q P++ Sbjct: 321 WRLGVI-----------AAHKDNVF------------------------DHALSQLPESA 345 Query: 314 QRCRDHMIRSLQSVGLKPIIPQGSYFLITDISDFKRKMPDLPGAVDEPYDRRFVKWMIKN 373 ++ DH RSL +PD+ +F+ ++ + Sbjct: 346 KKALDHRYRSL--------------------------LPDVRSL-------KFIDRLVAD 372 Query: 374 KGLVAIPVSIFYSVPHQKHFDHYIRFCFVKD-EATLQAMDEKLRKWKVEL 422 +VA+ + S P Q + F + + +A QA+ + +R+ + L Sbjct: 373 SRVVALNHTAGLSTPQQVQMVLFSLFALMDEADAYKQALKQLIRRREATL 422 >2ZYJ-A nrPDB Length = 397 Score = 45.4 bits (106), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 70/319 (21%), Positives = 125/319 (39%), Gaps = 47/319 (14%) Query: 20 EFVKLASEHDVVNLGQGFPD---FPPPDFAVEAFQHAVSGDFMLNQYTKTFGYPPLTKIL 76 E +KL +++ G P FP + A A + + QY+ T GY PL + Sbjct: 24 ELLKLTQRPGILSFAGGLPAPELFPKEEAAEAAARILREKGEVALQYSPTEGYAPLRAFV 83 Query: 77 ASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAG 136 A + G + P VL+T G AL + +DEG V++ P + + G Sbjct: 84 AEWIG------VRP-EEVLITTGSQQALDLVGKVFLDEGSPVLLEAPSYMGAIQAFRLQG 136 Query: 137 GRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREEL 196 P F++ + GE G LD +E K ++ + NP G + Sbjct: 137 --PRFLT-----VPAGEEGPD----LDALEEVLKRERPRFLYLIPSFQNPTGGLTPLPAR 185 Query: 197 ELVASLCQQHDVVCITDEVYQWMVYDGHQHISI------ASLPGMWERTLTIGSAGKTFS 250 + + + + +V + D+ Y+ + + + S+ A PG+ + +GS K S Sbjct: 186 KRLLQMVMERGLVVVEDDAYRELYFGEARLPSLFELAREAGYPGV----IYLGSFSKVLS 241 Query: 251 ATGWKVGWVLGPDHIMKHLRTVHQNSVFHCPTQSQAAV--------AESFEREQLLFRQP 302 G +V + + ++ L Q + H P +Q V +E ER + ++R+ Sbjct: 242 -PGLRVAFAVAHPEALQKLVQAKQGADLHTPMLNQMLVHELLKEGFSERLERVRRVYREK 300 Query: 303 SSYFVQFPQAMQRCRDHMI 321 + QAM D + Sbjct: 301 A-------QAMLHALDREV 312 >3TCM-A nrPDB Length = 500 Score = 45.1 bits (105), Expect = 6e-05, Method: Compositional matrix adjust. Identities = 69/336 (20%), Positives = 128/336 (38%), Gaps = 60/336 (17%) Query: 93 NVLVTVGGYGALFTAFQALV-DEGDEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPIQN 151 ++ +T G + Q L+ +E D +++ P + Y + GG +L P Sbjct: 159 DIFLTDGASPGVHLMMQLLIRNEKDGILVPIPQYPLYSASIALHGG-----ALVPY---- 209 Query: 152 GELGSSSNWQLDPMELAGKFTS------RTKALVLNTPNNPLGKVFSREELELVASLCQQ 205 L S+ W L+ ++ + +ALV+ P NP G+V + E + C+ Sbjct: 210 -YLNESTGWGLETSDVKKQLEDARSRGINVRALVVINPGNPTGQVLAEENQYDIVKFCKN 268 Query: 206 HDVVCITDEVYQWMVY----DGHQHISIASLPGMWERTLTI--------------GSAGK 247 +V + DEVYQ +Y H I G E L + G G Sbjct: 269 EGLVLLADEVYQENIYVDNKKFHSFKKIVRSLGYGEEDLPLVSYQSVSKGYYGECGKRGG 328 Query: 248 TFSATG---------WKVGWVLGPDHIMKHLRTVHQNSVFHCPTQSQAAVAE-SFEREQL 297 F TG +K+ V +I + + V + P S + A E++ + Sbjct: 329 YFEITGFSAPVREQIYKIASVNLCSNITGQILA---SLVMNPPKASDESYASYKAEKDGI 385 Query: 298 LFRQPSSYFVQFPQAMQRCRDHMIRSLQSVGLKPIIPQGSYFLITDISDFKRKMPDLPGA 357 L + + +A++ H L+ + +G+ ++ I +K + A Sbjct: 386 L-----ASLARRAKALE----HAFNKLEGITCNE--AEGAMYVFPQIC-LPQKAIEAAKA 433 Query: 358 VDEPYDRRFVKWMIKNKGLVAIPVSIFYSVPHQKHF 393 ++ D + ++++ G+V +P S F VP HF Sbjct: 434 ANKAPDAFYALRLLESTGIVVVPGSGFGQVPGTWHF 469 >3G7Q-A nrPDB Length = 417 Score = 43.5 bits (101), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 75/348 (21%), Positives = 134/348 (38%), Gaps = 32/348 (9%) Query: 82 ELLGQEIDPLRNVLVTVGGYGA---LFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGR 138 E LG +I+P +N+ +T G A LF F +G ++ P Y Sbjct: 90 ETLGWDIEP-QNIALTNGSQSAFFYLFNLFAGRRADGSTKKVLFPLAPEYIGYADSGLED 148 Query: 139 PVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELEL 198 +FVS +P N EL ++ T + ++ P NP G V + EEL Sbjct: 149 DLFVSARP----NIELLPEGQFKYHVDFEHLHIGEETGMICVSRPTNPTGNVITDEELMK 204 Query: 199 VASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTIGSAGKTFSATGWKVGW 258 + L QH++ + D Y + + G I + +W + + + G + G Sbjct: 205 LDRLANQHNIPLVIDNAYG-VPFPG---IIFSEARPLWNPNIILCMSLSKLGLPGSRCGI 260 Query: 259 VLGPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFPQAMQRCRD 318 ++ D + + ++ A + E +R LL + + Q +Q+ Sbjct: 261 IIANDKTITAIANMNGIISLAPGGMGPAMMCEMIKRNDLLRLSETVIKPFYYQRVQQTIA 320 Query: 319 HMIRSLQSVGLKPIIPQGSYFLITDISDFKRKMPDLPGAVDEPYDRRFVKWMIKNKGLVA 378 + R L P+G+ FL FK DLP + Y R +K +G++ Sbjct: 321 IIRRYLSEERCLIHKPEGAIFLWL---WFK----DLPITTELLYQR------LKARGVLM 367 Query: 379 IPVSIFYSVPHQ--KHFDHYIRFCFV----KDEATLQAMDEKL-RKWK 419 +P F+ + H +R +V K EA ++ + E++ R W+ Sbjct: 368 VPGHYFFPGLDKPWPHTHQCMRMNYVPEPDKIEAGVKILAEEIERAWR 415 >3QGU-A nrPDB Length = 449 Score = 43.1 bits (100), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 22/92 (23%), Positives = 42/92 (45%) Query: 174 RTKALVLNTPNNPLGKVFSREELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLP 233 RT + +PNNP G +R +L + + +++ + + D Y + + +I +P Sbjct: 209 RTDIIFFCSPNNPTGAAATRAQLTELVNFARKNGSILVYDAAYALYISNPDCPKTIYEIP 268 Query: 234 GMWERTLTIGSAGKTFSATGWKVGWVLGPDHI 265 G E + S K TG ++GW + P + Sbjct: 269 GADEVAIETCSFSKYAGFTGVRLGWTVVPKAL 300 >1UU1-A nrPDB Length = 335 Score = 42.4 bits (98), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 39/160 (24%), Positives = 65/160 (40%), Gaps = 19/160 (11%) Query: 182 TPNNPLGKVFSREELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTLT 241 PNNP G VF REE+E + + DE Y Y+ H S +E Sbjct: 146 NPNNPTGHVFEREEIERIL----KTGAFVALDEAY----YEFHGE-SYVDFLKKYENLAV 196 Query: 242 IGSAGKTFSATGWKVGWVLGPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQ 301 I + K FS +VG+V+ + + V +Q A VA RE +F + Sbjct: 197 IRTFSKAFSLAAQRVGYVVASEKFIDAYNRVRLPFNVSYVSQMFAKVALD-HRE--IFEE 253 Query: 302 PSSYFVQFPQAMQRCRDHMIRSLQSVGLKPIIPQGSYFLI 341 + + V+ R+ M +L+ +G + +G++ + Sbjct: 254 RTKFIVE-------ERERMKSALREMGYRITDSRGNFVFV 286 >5DJ3-A nrPDB Length = 376 Score = 42.0 bits (97), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 35/151 (23%), Positives = 59/151 (39%), Gaps = 18/151 (11%) Query: 116 DEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRT 175 D V ++ P FD + G L P++ L + +L+ + S Sbjct: 106 DRVALVHPTFDNIADLLRGNG-------LDLVPVEEDALHGA--------DLSAELLSSV 150 Query: 176 KALVLNTPNNPLGKVFSREELELVASLCQQHDVVCITDEVYQWMVYDGH-QHISIASLPG 234 + + TPNNP G+V + E L +A C +H V D ++ H H ++ G Sbjct: 151 GCVFVTTPNNPTGRVLAEERLRRLAEQCAEHGTVLALDTSFRGFDAAAHYDHYAVLQEAG 210 Query: 235 MWERTLTIGSAGKTFSATGWKVGWVLGPDHI 265 R + I GK + K G ++ + I Sbjct: 211 C--RWVVIEDTGKLWPTLDLKAGLLVFSEDI 239 >3GET-A nrPDB Length = 365 Score = 40.8 bits (94), Expect = 0.001, Method: Compositional matrix adjust. Identities = 45/224 (20%), Positives = 92/224 (41%), Gaps = 21/224 (9%) Query: 176 KALVLNTPNNPLGKVF-SREELELVASLCQQHDVVCITDEVYQWMVY--DGHQHISIASL 232 K + L PNNPLG+ + E E + + D + + D Y D +H+ L Sbjct: 155 KLIFLCLPNNPLGECLDASEATEFIKGV--NEDCLVVIDAAYNEFASFKDSKKHLEPCEL 212 Query: 233 PGMWERTLTIGSAGKTFSATGWKVGWVLGPDHIMKHLRTVHQNSVFHCPTQSQAAVAESF 292 ++ L +G+ K + G ++G+ + +I+ + + F+ + A + Sbjct: 213 IKEFDNVLYLGTFSKLYGLGGLRIGYGIANANIISAFYKLR--APFNVSNLALKAAVAAM 270 Query: 293 EREQLLFRQPSSYFVQFPQAMQRCRDHMIRSLQSVGLKPIIPQGSYFLITDISDFKRKMP 352 + ++ + + F Q + + H I+ II + F IT D ++ Sbjct: 271 DDDEFTEKTLENNFSQMELYKEFAKKHNIK---------IIDSYTNF-ITYFFD-EKNST 319 Query: 353 DLPGAVDEPYDRRFVKWMIKNKGLVAIPVSIFYSVPHQKHFDHY 396 DL ++ + + +K+ GL AI ++I S ++K F + Sbjct: 320 DLS---EKLLKKGIIIRNLKSYGLNAIRITIGTSYENEKFFTEF 360 >1IJI-A nrPDB Length = 356 Score = 40.0 bits (92), Expect = 0.002, Method: Compositional matrix adjust. Identities = 53/250 (21%), Positives = 99/250 (39%), Gaps = 24/250 (9%) Query: 44 DFAVEAFQHAVSGDFMLNQYTKTFGYPPLT-KILASFFGELLGQEIDPLRNVLVTVGGYG 102 D + A ++ + +F L Q T YP K + + + G + P VLV+ G Sbjct: 31 DVWLNANEYPTAVEFQLTQQTLN-RYPECQPKAVIENYAQYAG--VKP-EQVLVSRGADE 86 Query: 103 ALFTAFQALVDEG-DEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQ 161 + +A + G D ++ P + Y VS + ++ + + NWQ Sbjct: 87 GIELLIRAFCEPGKDAILYCPPTYGMYS------------VSAETIGVECRTVPTLDNWQ 134 Query: 162 LDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQQHDVVCITDEVYQWMVY 221 LD ++ K K + + +PNNP G++ + ++ + L + +V + DE Y Sbjct: 135 LDLQGISDKLDG-VKVVYVCSPNNPTGQLINPQDFRTLLELTRGKAIV-VADEAY----I 188 Query: 222 DGHQHISIASLPGMWERTLTIGSAGKTFSATGWKVGWVLGPDHIMKHLRTVHQNSVFHCP 281 + S+A + + + K F+ G + G+ L + ++ L V P Sbjct: 189 EFCPQASLAGWLAEYPHLAILRTLSKAFALAGLRCGFTLANEEVINLLMKVIAPYPLSTP 248 Query: 282 TQSQAAVAES 291 AA A S Sbjct: 249 VADIAAQALS 258 >1LC8-A nrPDB Length = 364 Score = 39.7 bits (91), Expect = 0.003, Method: Compositional matrix adjust. Identities = 42/173 (24%), Positives = 71/173 (41%), Gaps = 22/173 (12%) Query: 94 VLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGE 153 +L G ++FT L + +I+ P F Y +G I+ Sbjct: 79 ILAGNGETESIFTVASGL--KPRRAMIVTPGFAEYGRALAQSGCE----------IRRWS 126 Query: 154 LGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQQHDVVCITD 213 L + WQL L T L L TPNNP G + R L+ +A C+ ++ I D Sbjct: 127 LREADGWQLTDAILEA-LTPDLDCLFLCTPNNPTGLLPERPLLQAIADRCKSLNINLILD 185 Query: 214 EVYQWMVYDGHQHISIASL---PGMWERTLTIGSAGKTFSATGWKVGWVLGPD 263 E + + + H+ I +L P +W + S K ++ G ++G+++ D Sbjct: 186 EAF--IDFIPHETGFIPALKDNPHIW----VLRSLTKFYAIPGLRLGYLVNSD 232 >6HNV-A nrPDB Length = 524 Score = 38.1 bits (87), Expect = 0.008, Method: Compositional matrix adjust. Identities = 42/173 (24%), Positives = 68/173 (39%), Gaps = 8/173 (4%) Query: 62 QYTKTFGYPPLTKILASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVIII 121 QY G+ PL + F D NV +T G L A +D+GD +++ Sbjct: 129 QYAAVEGHAPLLQFARDFIIRTHKPNYDDW-NVFITTGASDGLNKAADVFLDDGDVILVE 187 Query: 122 EPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKF---TSRTKAL 178 E F + + AG + V V + N G +D +E K + KAL Sbjct: 188 EFTFSPFLRFSDNAGAKAVPVKIN---FDNDSDGIDLTQFVDLLENWEKHYPNLPKPKAL 244 Query: 179 -VLNTPNNPLGKVFSREELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIA 230 + T NP G S E + + L ++D I D+ Y ++ ++ +I Sbjct: 245 YTIATGQNPTGFTQSLEFRKKIYDLAVKYDFAIIEDDPYGYLTLPKYEKPNIG 297 >3UWC-A nrPDB Length = 374 Score = 38.1 bits (87), Expect = 0.008, Method: Compositional matrix adjust. Identities = 31/112 (27%), Positives = 47/112 (41%), Gaps = 19/112 (16%) Query: 100 GYGALFTAFQAL-VDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSS 158 G AL +F+ L + GDEVI F + AG PV V S + Sbjct: 62 GTDALAMSFKMLNIGAGDEVITCANTFIASVGAIVQAGATPVLVD------------SEN 109 Query: 159 NWQLDPMELAGKFTSRTKALV-----LNTPNNP-LGKVFSREELELVASLCQ 204 + +DP ++ T +TKA++ N + P L K+ + L +V CQ Sbjct: 110 GYVIDPEKIEAAITDKTKAIMPVHYTGNIADMPALAKIAKKHNLHIVEDACQ 161 >3IHJ-A nrPDB Length = 498 Score = 37.7 bits (86), Expect = 0.010, Method: Compositional matrix adjust. Identities = 47/193 (24%), Positives = 73/193 (37%), Gaps = 24/193 (12%) Query: 43 PDFAVEAFQHA-----VSGDFMLNQYTKTFGYPPLTKILASFFGELLGQEIDPLRNVLVT 97 P F +A + A G L Y+ + G + + +A++ G N+ +T Sbjct: 100 PSFPEDAKKRARRILQACGGNSLGSYSASQGVNCIREDVAAYITRRDGGVPADPDNIYLT 159 Query: 98 VGGYGALFTAFQALVDEGDE----VIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGE 153 G + T + LV G + V+I P + Y + V N Sbjct: 160 TGASDGISTILKILVSGGGKSRTGVMIPIPQYPLYSAVISELDAIQV----------NYY 209 Query: 154 LGSSSNWQLDPMEL-----AGKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQQHDV 208 L + W L+ EL K K L + P NP G+V SR+ +E V + + Sbjct: 210 LDEENCWALNVNELRRAVQEAKDHCDPKVLCIINPGNPTGQVQSRKCIEDVIHFAWEEKL 269 Query: 209 VCITDEVYQWMVY 221 + DEVYQ VY Sbjct: 270 FLLADEVYQDNVY 282 >4K2M-A nrPDB Length = 443 Score = 37.4 bits (85), Expect = 0.012, Method: Compositional matrix adjust. Identities = 31/123 (25%), Positives = 54/123 (43%), Gaps = 24/123 (19%) Query: 92 RNVLVTVGGYGALFTAFQAL-VDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPIQ 150 R V+ T G A+ AL ++ GDEVI+ F E + +GG P++V + P Sbjct: 119 RYVIATSSGTDAIMIGLLALGLNPGDEVIMPANSFSATENAVLASGGVPIYVDINP---- 174 Query: 151 NGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGK---------VFSREELELVAS 201 + +DP ++ T TK ++ P + GK + +R +L+++ Sbjct: 175 -------QTFCIDPDKIEEAITPYTKFIL---PVHLYGKHSDMQHIRQIANRYKLKVIED 224 Query: 202 LCQ 204 CQ Sbjct: 225 ACQ 227 >6HNB-A nrPDB Length = 491 Score = 37.4 bits (85), Expect = 0.013, Method: Compositional matrix adjust. Identities = 57/264 (21%), Positives = 100/264 (37%), Gaps = 51/264 (19%) Query: 62 QYTKTFGYPPLTKILASFFGELLGQEID-----PLRN--VLVTVGGYGALFTAFQALVDE 114 QY TFG P F + + + D P N V+V+VG A + + + Sbjct: 104 QYGSTFGLPE--------FLQFIKEHTDMVHKVPYENWDVIVSVGNTEAWDSTLRTFCSK 155 Query: 115 GDEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSR 174 GD +++ E F G V V++ I +L EL ++ Sbjct: 156 GDTILVEEYTFSSALESANGQGVNTVPVTMDEFGIIPEKL----------EELMSRWVGN 205 Query: 175 TKALV--LNTPNNPLGKVFSREELELVASLCQQHDVVCITDEVYQWM------------- 219 + + T NP G S E + + + ++D + I DE Y ++ Sbjct: 206 KPKFLYTICTGQNPTGSSLSAERRKQIYDIACKYDFLIIEDEPYYFLQMETYTKDKAARE 265 Query: 220 ---VYDGHQHISIASLPGMWE-----RTLTIGSAGKTFSATGWKVGWVLGPDHIMKHLRT 271 V+D H A +P R + + S K A G ++GW++G +++ Sbjct: 266 GKAVHD-HDEFLKALVPSFISLDVEGRVVRLDSFSKVL-APGLRLGWIVGQKDLLERYVR 323 Query: 272 VHQNSVFHCPTQSQAAVAESFERE 295 +H+ SV P+ A+A + R+ Sbjct: 324 LHEVSV-QNPSGFSEALANALLRK 346 >6C3C-A nrPDB Length = 413 Score = 37.0 bits (84), Expect = 0.017, Method: Compositional matrix adjust. Identities = 49/200 (24%), Positives = 79/200 (39%), Gaps = 37/200 (18%) Query: 97 TVGGYGALFTAFQA---LVDEGDEVIIIEPFFD-CYEPMTMMAGGRPVFVSLKPGPIQNG 152 T+ Y A + A L E V +IEP FD Y+ + M V L P Sbjct: 108 TMLSYAASISTMVAGMFLKKERLAVTLIEPCFDNLYDVLANMD------VPLYP------ 155 Query: 153 ELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFS-----REELELVASLCQQHD 207 + S + +D + + RT AL L PNNP G FS R+ E V C+ HD Sbjct: 156 -IDESVFYDVDRIYPELERRVRTDALFLVDPNNPTG--FSLLRHGRKGFEEVVRFCKDHD 212 Query: 208 VVCITDEVY--------QWMVYDGHQHISIASLPGMWERTLTIGSAGKTFSATGWKVGWV 259 + + D + + +D ++ + + + R L I GKT+ K + Sbjct: 213 KLLLIDFCFASFTLFEPELARFDMYELLENSGV-----RYLAIEDTGKTWPVQDAKCALI 267 Query: 260 LGPDHIMKHLRTVHQNSVFH 279 D I + + +H + + + Sbjct: 268 TASDDIWETVYNLHTSVLLN 287 >5K8B-A nrPDB Length = 403 Score = 35.4 bits (80), Expect = 0.047, Method: Compositional matrix adjust. Identities = 32/133 (24%), Positives = 59/133 (44%), Gaps = 20/133 (15%) Query: 82 ELLGQEIDPLRNVLVTVGGYGALFTAFQAL-VDEGDEVIIIEPFFDCYEPMTMMAGGRPV 140 +LL ++++ +++ + G AL TA A + GDEVI+ F MAG P+ Sbjct: 44 QLLCEKMN-VKHAHLLSSGTAALQTAMMAAGIGAGDEVIVPPFTFVASVEAIFMAGAVPI 102 Query: 141 FVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVA 200 F + L P + T RTKA+ N + S +++ + Sbjct: 103 FAEI------------DETLCLSPEGIEAVITPRTKAI------NLVHMCGSMAKMDEIK 144 Query: 201 SLCQQHDVVCITD 213 ++C++H++V + D Sbjct: 145 AICKKHNLVLLED 157 >4JE5-A nrPDB Length = 503 Score = 35.4 bits (80), Expect = 0.048, Method: Compositional matrix adjust. Identities = 47/225 (20%), Positives = 89/225 (39%), Gaps = 30/225 (13%) Query: 93 NVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNG 152 +VL T G A + + + GD VI++E + + +A V P PI Sbjct: 137 DVLATAGNTNAWESTLRVFCNRGD-VILVE----AHSFSSSLASAEAQGVITFPVPIDAD 191 Query: 153 ELGSSSNWQLDPMELAGKFTSRTKAL-VLNTPNNPLGKVFSREELELVASLCQQHDVVCI 211 + ++ ME + K L + T NP G + E + + Q++D + + Sbjct: 192 GIIPEKLAKV--MENWTPGAPKPKLLYTIPTGQNPTGTSIADHRKEAIYKIAQKYDFLIV 249 Query: 212 TDEVYQWM-----VYDGHQHISIASLP---------GMWERTLTIGSAGK-----TFS-- 250 DE Y ++ + D + S P + L++ + G+ +FS Sbjct: 250 EDEPYYFLQMNPYIKDLKEREKAQSSPKQDHDEFLKSLANTFLSLDTEGRVIRMDSFSKV 309 Query: 251 -ATGWKVGWVLGPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFER 294 A G ++GW+ G I+K ++H+ ++ +Q V + R Sbjct: 310 LAPGTRLGWITGSSKILKPYLSLHEMTIQAPAGFTQVLVNATLSR 354 >3P1T-A nrPDB Length = 337 Score = 35.0 bits (79), Expect = 0.056, Method: Compositional matrix adjust. Identities = 25/99 (25%), Positives = 44/99 (44%), Gaps = 10/99 (10%) Query: 172 TSRTKALVLNTPNNPLGKVFSREELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIAS 231 SR +VL P+NP G+ S EL+ + +Q + DE Y + Y + +A Sbjct: 133 VSRDDCVVLANPSNPTGQALSAGELDQL----RQRAGKLLIDETY--VDYSSFRARGLA- 185 Query: 232 LPGMWERTLTIGSAGKTFSATGWKVGWVLGPDHIMKHLR 270 E L S K++ G ++G + GP ++ ++ Sbjct: 186 ---YGENELVFRSFSKSYGLAGLRLGALFGPSELIAAMK 221 >4L0O-H nrPDB Length = 388 Score = 33.5 bits (75), Expect = 0.19, Method: Compositional matrix adjust. Identities = 18/48 (37%), Positives = 26/48 (54%), Gaps = 3/48 (6%) Query: 174 RTKALVLNTPNNPLGKVFSREELELVASLCQQHDVVCITDEVYQWMVY 221 TKAL L TP+NPL K+ +L AS+ + H ++ I D + Y Sbjct: 134 NTKALYLETPSNPLLKI---TDLAQCASVAKDHGLLTIVDNTFATPYY 178 >3MKJ-A nrPDB Length = 398 Score = 33.1 bits (74), Expect = 0.21, Method: Compositional matrix adjust. Identities = 26/122 (21%), Positives = 43/122 (35%), Gaps = 16/122 (13%) Query: 95 LVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGEL 154 L T G A+ T L +GD ++ + C ++ P F + Sbjct: 83 LATASGISAITTTLLTLCQQGDHIVSASAIYGCTH--AFLSHSMPKF-----------GI 129 Query: 155 GSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQQHDVVCITDE 214 S P E+ TK + + TP NP S ++E VA + Q + + D Sbjct: 130 NVSFVDAAKPEEIRAAMRPETKVVYIETPANP---TLSLVDIETVAGIAHQQGALLVVDN 186 Query: 215 VY 216 + Sbjct: 187 TF 188 >3NYS-A nrPDB Length = 367 Score = 32.3 bits (72), Expect = 0.36, Method: Compositional matrix adjust. Identities = 34/130 (26%), Positives = 50/130 (38%), Gaps = 25/130 (19%) Query: 83 LLGQEIDPLRNVLV----------TVGGYGALFTAFQAL-VDEGDEVIIIEPFFDCYEPM 131 +LG E+ L + L G AL AL V GDEVI + Sbjct: 32 ILGPEVTELEDRLADFVGAKYCISCANGTDALQIVQMALGVGPGDEVITPGFTYVATAET 91 Query: 132 TMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVF 191 + G +PV+V + P + LDP L T RTKA++ P + G+ Sbjct: 92 VALLGAKPVYVDIDP-----------RTYNLDPQLLEAAITPRTKAII---PVSLYGQCA 137 Query: 192 SREELELVAS 201 + + +AS Sbjct: 138 DFDAINAIAS 147 >2X5F-A nrPDB Length = 430 Score = 32.3 bits (72), Expect = 0.37, Method: Compositional matrix adjust. Identities = 23/91 (25%), Positives = 44/91 (48%), Gaps = 9/91 (9%) Query: 178 LVLNTPNNPLGKVFSREE----LELVASLCQQ-HDVVCITDEVYQWMVY-DGHQHISIAS 231 ++LN PNNP G + +E +E + +L + V+ + D+ Y + Y D + + Sbjct: 193 MILNYPNNPTGYTPTHKEVTTIVEAIKALANKGTKVIAVVDDAYYGLFYEDVYTQSLFTA 252 Query: 232 LPGMWERT---LTIGSAGKTFSATGWKVGWV 259 L + + + A K F A G++VG++ Sbjct: 253 LTNLHSNAILPIRLDGATKEFFAWGFRVGFM 283 >2FNU-A nrPDB Length = 375 Score = 32.3 bits (72), Expect = 0.39, Method: Compositional matrix adjust. Identities = 30/126 (23%), Positives = 54/126 (42%), Gaps = 21/126 (16%) Query: 91 LRNVLVTVGGYGALFTAFQALVD---EGDEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPG 147 +++ LV AL T ++ + + +E+I F M + +G PVF +K Sbjct: 47 VKHALVFNSATSALLTLYRNFSEFSADRNEIITTPISFVATANMLLESGYTPVFAGIK-- 104 Query: 148 PIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQQHD 207 ++ +D + L RTKA+V + GK E+E V LC++H Sbjct: 105 ----------NDGNIDELALEKLINERTKAIV---SVDYAGKSV---EVESVQKLCKKHS 148 Query: 208 VVCITD 213 + ++D Sbjct: 149 LSFLSD 154 >6CJB-A nrPDB Length = 391 Score = 32.3 bits (72), Expect = 0.44, Method: Compositional matrix adjust. Identities = 14/53 (26%), Positives = 30/53 (56%), Gaps = 3/53 (5%) Query: 164 PMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQQHDVVCITDEVY 216 P + T +TK L L TP+NP+ K+ L +A++ ++++++ + D + Sbjct: 136 PENIEAAITPKTKLLWLETPSNPMLKL---ANLRKIAAIAKKYNLITVADNTF 185 >4EMY-A nrPDB Length = 413 Score = 32.0 bits (71), Expect = 0.55, Method: Compositional matrix adjust. Identities = 38/178 (21%), Positives = 70/178 (39%), Gaps = 14/178 (7%) Query: 93 NVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNG 152 + + T GG GA+ +A + +DEGD +I + ++ Y + G + K Sbjct: 103 SAIATPGGTGAIRSAIFSYLDEGDPLICHDYYWAPYRKICEEFGR-----NFKTFEFFTD 157 Query: 153 ELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASLC------QQH 206 + + + + ++ + + R +L+ + NNP G S EE + V + + Sbjct: 158 DFAFNIDVYKEAIDEGIRDSDRIASLINSPGNNPTGYSLSDEEWDEVITFLKEKAEDKDK 217 Query: 207 DVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTIG---SAGKTFSATGWKVGWVLG 261 + I D Y DG Q R L + S K+ +A G + G +G Sbjct: 218 KITLIVDVAYLEFAGDGDQQRKFFEKFSNLPRNLFVVVAFSMSKSHTAYGLRSGAAVG 275 >3EUC-A nrPDB Length = 367 Score = 31.6 bits (70), Expect = 0.68, Method: Compositional matrix adjust. Identities = 52/246 (21%), Positives = 92/246 (37%), Gaps = 43/246 (17%) Query: 158 SNWQLDPMELAGKFTSRTKALV-LNTPNNPLGKVFSREELELVASLCQQHDVVC----IT 212 +++ LD + A+V L PNNP G +F ++E + Q VC + Sbjct: 140 ADFTLDRGAMLAAMAEHQPAIVYLAYPNNPTGNLFDAADMEAIVRAAQGS--VCRSLVVV 197 Query: 213 DEVYQ------WMVYDGHQHISIASLPGMWERTLTIGSAGKTFSATGWKVGWVLGPDHIM 266 DE YQ WM + +L M RT++ G ++G+V G + Sbjct: 198 DEAYQPFAQESWM----SRLTDFGNLLVM--RTVS------KLGLAGIRLGYVAGDPQWL 245 Query: 267 KHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFPQAMQRCRDHMIRSLQS 326 + L V + T++ A A E +L Q + + R + + + Sbjct: 246 EQLDKVRPPYNVNVLTEATALFA--LEHVAVLDEQAAQLRAE--------RSRVAEGMAA 295 Query: 327 VGLKPIIPQGSYFLITDISDFKRKMPDLPGAVDEPYDRR-FVKWMIKNKGLVAIPVSIFY 385 G + P + FL+ ++PD D R+ +K + K L+A + + Sbjct: 296 HGGVTVFPSAANFLLA-------RVPDAAQTFDRLLARKVLIKNVSKMHPLLANCLRVTV 348 Query: 386 SVPHQK 391 S P + Sbjct: 349 STPEEN 354 >6CC2-A nrPDB Length = 543 Score = 31.6 bits (70), Expect = 0.73, Method: Compositional matrix adjust. Identities = 19/52 (36%), Positives = 23/52 (44%), Gaps = 1/52 (1%) Query: 354 LPGAVDEPYDRRFVKWMIKNKGLVAIPVSIFYSVPHQKHFDHYIRFCFVKDE 405 L EPYD F K + NK LV + + S + Y RFC V DE Sbjct: 385 LSSTTAEPYDFGFAKCIESNKNLVETGIILLLSGSCFNEANKY-RFCSVSDE 435 >3FTB-A nrPDB Length = 361 Score = 31.2 bits (69), Expect = 0.89, Method: Compositional matrix adjust. Identities = 30/143 (20%), Positives = 56/143 (39%), Gaps = 15/143 (10%) Query: 116 DEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRT 175 ++++II P + YE G VF L N +D ++ K Sbjct: 99 EKILIIVPSYAEYEINAKKHGVSVVFSYL------------DENMCIDYEDIISKIDD-V 145 Query: 176 KALVLNTPNNPLGKVFSREELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGM 235 ++++ PNNP G + ++E+ V L ++ I DE + + + G S Sbjct: 146 DSVIIGNPNNPNGGLINKEKFIHVLKLAEEKKKTIIIDEAF--IEFTGDPSSSFVGEIKN 203 Query: 236 WERTLTIGSAGKTFSATGWKVGW 258 + I + K F+ G + G+ Sbjct: 204 YSCLFIIRAMTKFFAMPGIRFGY 226 >3VK2-A nrPDB Length = 398 Score = 30.4 bits (67), Expect = 1.3, Method: Compositional matrix adjust. Identities = 70/311 (22%), Positives = 105/311 (33%), Gaps = 69/311 (22%) Query: 43 PDFAVEAFQHAV-----SGDFMLNQY-TKTFGYPPLTKILASFFGELLG----QEIDPLR 92 P FA A H G + Y T TF +P + A F GE G + +P Sbjct: 8 PGFATRAIHHGYDPQDHGGALVPPVYQTATFTFPTVEYGAACFAGEQAGHFYSRISNPTL 67 Query: 93 NVL--------------VTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGR 138 N+L G GA+ + L+ GDEV++ + Sbjct: 68 NLLEARMASLEGGEAGLALASGMGAITSTLWTLLRPGDEVLLGNTLYG------------ 115 Query: 139 PVFVSLKPGPIQNGELGSSSNW--QLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREEL 196 F L G GE G D L T T+ + +P NP ++ Sbjct: 116 HTFAFLHHGI---GEFGVKLRHVDMADLQALEAAMTPATRVIYFESPANP---NMHMADI 169 Query: 197 ELVASLCQQHDVVCITDEVYQW--------MVYDGHQHISIASLPGMWERT--LTIGSAG 246 VA + ++H + D Y + D H + L G + T + +GS Sbjct: 170 AGVAKIARKHGATVVVDNTYCTPYLQRPLELGADLVVHSATKYLSGHGDITAGIVVGSQA 229 Query: 247 --KTFSATGWK--VGWVLGPDH---IMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLF 299 G K G VL P +M+ ++T++ HC + A V F L Sbjct: 230 LVDRIRLQGLKDMTGAVLSPHDAALLMRGIKTLNLRMDRHC---ANAQVLAEF-----LA 281 Query: 300 RQPSSYFVQFP 310 RQP + +P Sbjct: 282 RQPQVELIHYP 292 >1UTY-A nrPDB Length = 187 Score = 30.4 bits (67), Expect = 1.5, Method: Compositional matrix adjust. Identities = 15/31 (48%), Positives = 21/31 (67%), Gaps = 1/31 (3%) Query: 345 SDFKR-KMPDLPGAVDEPYDRRFVKWMIKNK 374 +DF R +MPDLPG + YD R ++ IKN+ Sbjct: 134 NDFDRNEMPDLPGVMRSNYDIRELRQKIKNE 164 >5Y2C-A nrPDB Length = 383 Score = 29.6 bits (65), Expect = 2.5, Method: Compositional matrix adjust. Identities = 15/35 (42%), Positives = 19/35 (54%) Query: 153 ELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPL 187 ELG S W LD + GK+ KA +L T N+ L Sbjct: 336 ELGGSMAWSLDLDDFTGKYCGCGKAPLLTTINHVL 370 >5ZVG-B nrPDB Length = 384 Score = 29.3 bits (64), Expect = 3.1, Method: Compositional matrix adjust. Identities = 17/61 (27%), Positives = 32/61 (52%), Gaps = 7/61 (11%) Query: 299 FRQPSSYFVQFPQAMQRCRDHMIRSLQSVGLKPI----IPQGSYFLITDIS---DFKRKM 351 R+P ++ ++ R+ +I L+ GLKP+ +P+G YF+ + DF+ K+ Sbjct: 29 LREPVEHYYIRVNTLKISREKLIGELKKEGLKPLRSPYLPEGLYFVREGPNFSDDFEPKL 88 Query: 352 P 352 P Sbjct: 89 P 89 >4IYO-A nrPDB Length = 397 Score = 28.9 bits (63), Expect = 4.9, Method: Compositional matrix adjust. Identities = 12/54 (22%), Positives = 27/54 (50%), Gaps = 3/54 (5%) Query: 163 DPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQQHDVVCITDEVY 216 DP + TK + + TP NP+ K+ ++ +A + ++H ++ + D + Sbjct: 138 DPAAFKAAIRADTKMVWIETPTNPMLKLV---DIAAIAVIARKHGLLTVVDNTF 188 >5TSU-A nrPDB Length = 422 Score = 28.5 bits (62), Expect = 5.9, Method: Compositional matrix adjust. Identities = 22/92 (23%), Positives = 39/92 (42%), Gaps = 19/92 (20%) Query: 167 LAGKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQQH-DVVCITDEVYQWMVYDGHQ 225 L T TK + + TP NP KV ++E A + +H D++ + D + Sbjct: 160 LEAAITPETKLVWIETPTNPTQKVI---DIEGCAHIVHKHGDIILVVDNTF--------- 207 Query: 226 HISIASLPGMWERTLTIGSAGKTFSATGWKVG 257 + ++R L +G+ +SAT + G Sbjct: 208 ------MSPYFQRPLALGADISMYSATKYMNG 233 >3RQ1-A nrPDB Length = 418 Score = 28.1 bits (61), Expect = 7.3, Method: Compositional matrix adjust. Identities = 42/168 (25%), Positives = 69/168 (41%), Gaps = 15/168 (8%) Query: 50 FQHAVSGDFMLNQYTKTFGYPPLTKI---LASFFGELLGQEIDPLRNV--LVTVGGYGAL 104 F V +++ ++ GY P+ I L + E G P ++ + T GG G + Sbjct: 57 FLKTVKEEYLSLSDSEHVGYAPIAGIPDFLCAAEKECFGN-FRPEGHIRSIATAGGTGGI 115 Query: 105 FTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDP 164 + GDEV+ + ++ Y + G V SL + +Q Sbjct: 116 HHLIHNYTEPGDEVLTADWYWGAYRVICSDTGRTLVTYSL----FDEHNNFNHEAFQNRV 171 Query: 165 MELAGKFTSRTKALVLNTP-NNPLGKVFSREELELVASLCQQHDVVCI 211 ELA K T+ ++ NTP NNP G +S E+ + + L D+V I Sbjct: 172 NELAAKQTNVV--VIFNTPGNNPTG--YSIEDKDWDSILNFLKDLVAI 215 >6ERK-A nrPDB Length = 451 Score = 28.1 bits (61), Expect = 8.5, Method: Compositional matrix adjust. Identities = 10/27 (37%), Positives = 19/27 (70%) Query: 189 KVFSREELELVASLCQQHDVVCITDEV 215 + +S + L+L+ LC ++DV+ I DE+ Sbjct: 243 RFYSPQYLQLLRKLCDEYDVLLIADEI 269 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 4WP0-A nrPDB 554 e-158 3FVS-A nrPDB 554 e-158 2ZJG-A nrPDB 455 e-128 1YIY-A nrPDB 416 e-116 1GDE-A nrPDB 371 e-103 1U08-A nrPDB 357 4e-99 6F77-B nrPDB 349 1e-96 6F35-A nrPDB 342 1e-94 2X5D-A nrPDB 341 3e-94 1J32-A nrPDB 341 3e-94 1GC4-A nrPDB 341 4e-94 5WMH-A nrPDB 341 5e-94 3B46-A nrPDB 338 3e-93 1O4S-A nrPDB 333 8e-92 2O0R-A nrPDB 324 3e-89 4MY5-A nrPDB 310 5e-85 2Z61-A nrPDB 310 5e-85 1V2E-A nrPDB 307 8e-84 5YHV-A nrPDB 292 1e-79 1XI9-A nrPDB 292 2e-79 3PDX-A nrPDB 278 3e-75 3H14-A nrPDB 277 8e-75 3DYD-A nrPDB 276 1e-74 3AV7-A nrPDB 274 4e-74 1X0M-A nrPDB 272 2e-73 3JTX-A nrPDB 266 2e-71 1WST-A nrPDB 256 1e-68 2O1B-A nrPDB 253 9e-68 2ZC0-A nrPDB 249 1e-66 3ELE-A nrPDB 248 3e-66 2GB3-A nrPDB 244 6e-65 1VP4-A nrPDB 243 2e-64 1BW0-A nrPDB 238 4e-63 1IAY-A nrPDB 236 1e-62 4FL0-A nrPDB 236 1e-62 4IX8-A nrPDB 235 3e-62 4CVQ-A nrPDB 234 6e-62 4DQ6-A nrPDB 234 7e-62 5Z0Q-C nrPDB 224 5e-59 2DOU-A nrPDB 223 1e-58 3L8A-A nrPDB 222 2e-58 3ASB-A nrPDB 222 2e-58 3T32-A nrPDB 221 5e-58 3B1C-A nrPDB 221 6e-58 3NRA-A nrPDB 220 1e-57 3G7Q-A nrPDB 214 5e-56 3OP7-A nrPDB 214 6e-56 1M4N-A nrPDB 213 1e-55 3EI8-A nrPDB 211 4e-55 3QGU-A nrPDB 210 7e-55 3EZS-A nrPDB 203 2e-52 2ZYJ-A nrPDB 202 2e-52 3FDB-A nrPDB 197 7e-51 4GDY-A nrPDB 196 1e-50 1C7O-A nrPDB 195 4e-50 3IF2-A nrPDB 188 5e-48 3TCM-A nrPDB 184 8e-47 4M2J-A nrPDB 183 1e-46 3DZZ-A nrPDB 182 2e-46 4R2N-A nrPDB 175 4e-44 3HDO-A nrPDB 171 4e-43 1IJI-A nrPDB 166 2e-41 2ZY3-A nrPDB 163 2e-40 3G0T-A nrPDB 161 7e-40 2ZY2-A nrPDB 161 7e-40 3FDD-A nrPDB 158 6e-39 3GET-A nrPDB 157 7e-39 1D2F-A nrPDB 155 3e-38 3F6T-A nrPDB 153 1e-37 1UU1-A nrPDB 138 3e-33 5DJ3-A nrPDB 112 2e-25 Sequences not found previously or not previously below threshold: 6HNV-A nrPDB 164 8e-41 3IHJ-A nrPDB 159 2e-39 6HNB-A nrPDB 147 9e-36 3CQ5-A nrPDB 134 9e-32 4JE5-A nrPDB 131 7e-31 4RAE-A nrPDB 124 8e-29 3FFH-A nrPDB 122 3e-28 3EUC-A nrPDB 122 4e-28 3FTB-A nrPDB 115 3e-26 3LY1-A nrPDB 111 7e-25 3P1T-A nrPDB 107 7e-24 4WBT-A nrPDB 106 2e-23 4N0B-A nrPDB 106 2e-23 3FKD-A nrPDB 106 2e-23 1LC8-A nrPDB 103 2e-22 3RQ1-A nrPDB 102 4e-22 5X03-B nrPDB 101 4e-22 2X5F-A nrPDB 100 1e-21 3FSL-A nrPDB 95 7e-20 4F5M-A nrPDB 91 7e-19 4EMY-A nrPDB 90 2e-18 6C3C-A nrPDB 89 3e-18 4WD2-A nrPDB 89 3e-18 3EZ1-A nrPDB 84 7e-17 1AY8-A nrPDB 82 5e-16 3PD6-B nrPDB 81 9e-16 4RKC-A nrPDB 81 9e-16 4W5K-A nrPDB 78 8e-15 1TAR-A nrPDB 76 3e-14 2CST-A nrPDB 76 3e-14 3BWN-A nrPDB 74 8e-14 4WB0-B nrPDB 74 1e-13 4H51-A nrPDB 71 8e-13 4K2M-A nrPDB 69 4e-12 2X8U-A nrPDB 68 9e-12 3MEB-A nrPDB 67 1e-11 1YAA-A nrPDB 67 2e-11 1M6S-A nrPDB 67 2e-11 5C6U-A nrPDB 66 2e-11 6EZL-A nrPDB 66 3e-11 4EFF-A nrPDB 66 3e-11 3NYS-A nrPDB 65 5e-11 3VK2-A nrPDB 65 6e-11 3DR4-A nrPDB 65 6e-11 3A2B-A nrPDB 64 9e-11 3II0-A nrPDB 64 1e-10 4PIW-A nrPDB 64 2e-10 2C81-A nrPDB 63 3e-10 5TON-A nrPDB 62 4e-10 3K7Y-A nrPDB 62 4e-10 4W91-A nrPDB 61 7e-10 4LW2-A nrPDB 61 7e-10 5XT5-A nrPDB 61 8e-10 6ONN-A nrPDB 61 8e-10 2OGE-A nrPDB 61 1e-09 4OC9-A nrPDB 60 2e-09 3UWC-A nrPDB 60 2e-09 3WGB-A nrPDB 59 3e-09 5JAY-A nrPDB 59 3e-09 1E5F-A nrPDB 59 3e-09 1MDZ-A nrPDB 59 4e-09 6CJB-A nrPDB 57 2e-08 2HOR-A nrPDB 56 3e-08 4L0O-H nrPDB 56 3e-08 1CS1-A nrPDB 56 4e-08 3BB8-A nrPDB 55 6e-08 6BLG-A nrPDB 55 7e-08 3QI6-A nrPDB 54 1e-07 5X5H-A nrPDB 54 1e-07 5W70-A nrPDB 54 1e-07 5K8B-A nrPDB 53 3e-07 3AEO-A nrPDB 53 3e-07 3WY7-A nrPDB 53 3e-07 1B9H-A nrPDB 52 4e-07 1N8P-A nrPDB 52 4e-07 5IJG-A nrPDB 52 5e-07 5TSU-A nrPDB 52 5e-07 5W1B-A nrPDB 52 6e-07 5I92-A nrPDB 51 7e-07 4BMK-A nrPDB 51 8e-07 2GMS-A nrPDB 51 1e-06 1IBJ-A nrPDB 50 2e-06 1FC4-A nrPDB 49 3e-06 5VC2-A nrPDB 49 3e-06 3G8M-A nrPDB 49 5e-06 2CTZ-A nrPDB 48 6e-06 2E7J-A nrPDB 47 1e-05 4U1T-A nrPDB 47 1e-05 4GSA-A nrPDB 47 2e-05 3GBX-A nrPDB 47 2e-05 4IYO-A nrPDB 47 2e-05 4ADC-A nrPDB 47 2e-05 5VPR-A nrPDB 46 2e-05 2CB1-A nrPDB 46 3e-05 4P3M-A nrPDB 45 8e-05 2DR1-A nrPDB 44 1e-04 3NDN-A nrPDB 44 1e-04 5VMB-A nrPDB 43 2e-04 4JF0-A nrPDB 43 3e-04 6FYQ-A nrPDB 42 4e-04 3N0L-A nrPDB 42 5e-04 4J5U-A nrPDB 41 8e-04 1SVV-A nrPDB 41 9e-04 4QGR-A nrPDB 41 0.001 4PPM-A nrPDB 41 0.001 3ISL-A nrPDB 41 0.001 3RUY-A nrPDB 41 0.001 3LVM-A nrPDB 41 0.001 5WGB-A nrPDB 41 0.001 3NTJ-A nrPDB 40 0.002 1VJO-A nrPDB 40 0.002 3GZD-A nrPDB 40 0.002 4OTL-A nrPDB 40 0.002 4Q6R-A nrPDB 40 0.003 3RI6-A nrPDB 39 0.003 4OBV-D nrPDB 39 0.004 3NNK-A nrPDB 39 0.004 2EH6-A nrPDB 39 0.004 5TXT-B nrPDB 39 0.004 5YKR-A nrPDB 39 0.004 3WKR-A nrPDB 39 0.005 2DKJ-A nrPDB 39 0.005 3HMU-A nrPDB 39 0.005 6JEQ-A nrPDB 38 0.008 6ERK-A nrPDB 38 0.009 2FNU-A nrPDB 38 0.009 1Z7D-A nrPDB 38 0.009 2E54-A nrPDB 38 0.010 5VYE-A nrPDB 37 0.010 1O69-A nrPDB 37 0.011 4EB7-A nrPDB 37 0.014 6G4F-A nrPDB 37 0.014 3MC6-C nrPDB 37 0.018 3ECD-A nrPDB 37 0.019 5VIU-A nrPDB 37 0.019 2CY8-A nrPDB 36 0.023 2EO5-A nrPDB 36 0.025 6CBN-A nrPDB 36 0.027 3HQT-A nrPDB 36 0.034 3I5T-A nrPDB 36 0.038 2FQ6-A nrPDB 36 0.042 5LH9-A nrPDB 36 0.042 2CH1-A nrPDB 36 0.047 1DJ9-A nrPDB 36 0.049 5M46-A nrPDB 35 0.060 5LL2-A nrPDB 35 0.069 3DOD-A nrPDB 35 0.081 4E3Q-A nrPDB 34 0.093 1I43-A nrPDB 34 0.099 4WXB-A nrPDB 34 0.12 1SFF-A nrPDB 34 0.14 3N5M-A nrPDB 34 0.18 2ZUK-A nrPDB 33 0.20 2JIS-A nrPDB 33 0.23 1ORD-A nrPDB 33 0.23 3GJU-A nrPDB 33 0.31 1EA9-C nrPDB 32 0.32 5KR6-A nrPDB 32 0.33 6GWI-A nrPDB 32 0.34 5EAV-A nrPDB 32 0.34 4BQ0-A nrPDB 32 0.41 5KR3-A nrPDB 32 0.46 6GIO-D nrPDB 32 0.53 2Z9W-A nrPDB 32 0.54 4WYG-A nrPDB 32 0.68 5KQW-A nrPDB 32 0.69 4IW7-A nrPDB 31 0.71 6IO1-A nrPDB 31 0.77 3DOR-A nrPDB 31 0.78 1W3H-A nrPDB 31 0.88 4LNN-A nrPDB 31 0.93 1J0H-A nrPDB 31 0.96 5KQT-A nrPDB 31 1.0 4UHN-A nrPDB 31 1.2 1SMA-A nrPDB 31 1.3 1SPI-A nrPDB 31 1.3 3FXW-A nrPDB 31 1.4 5IZ1-A nrPDB 31 1.4 4OKD-A nrPDB 31 1.5 5JZX-A nrPDB 30 1.9 4BA4-A nrPDB 30 2.2 5KQU-A nrPDB 30 2.3 5KR5-A nrPDB 30 2.4 1OAT-A nrPDB 29 2.8 2E8Y-A nrPDB 29 3.1 1WA5-C nrPDB 29 3.1 5OQM-k nrPDB 29 3.1 4RIT-B nrPDB 29 3.4 1V3M-A nrPDB 29 3.5 3A8U-X nrPDB 29 4.7 2D3T-A nrPDB 29 5.8 4ATY-A nrPDB 28 9.8 >4WP0-A nrPDB Length = 472 Score = 554 bits (1428), Expect = e-158, Method: Composition-based stats. Identities = 422/422 (100%), Positives = 422/422 (100%) Query: 1 MAKQLQARRLDGIDYNPWVEFVKLASEHDVVNLGQGFPDFPPPDFAVEAFQHAVSGDFML 60 MAKQLQARRLDGIDYNPWVEFVKLASEHDVVNLGQGFPDFPPPDFAVEAFQHAVSGDFML Sbjct: 1 MAKQLQARRLDGIDYNPWVEFVKLASEHDVVNLGQGFPDFPPPDFAVEAFQHAVSGDFML 60 Query: 61 NQYTKTFGYPPLTKILASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVII 120 NQYTKTFGYPPLTKILASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVII Sbjct: 61 NQYTKTFGYPPLTKILASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVII 120 Query: 121 IEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVL 180 IEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVL Sbjct: 121 IEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVL 180 Query: 181 NTPNNPLGKVFSREELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTL 240 NTPNNPLGKVFSREELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTL Sbjct: 181 NTPNNPLGKVFSREELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTL 240 Query: 241 TIGSAGKTFSATGWKVGWVLGPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFR 300 TIGSAGKTFSATGWKVGWVLGPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFR Sbjct: 241 TIGSAGKTFSATGWKVGWVLGPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFR 300 Query: 301 QPSSYFVQFPQAMQRCRDHMIRSLQSVGLKPIIPQGSYFLITDISDFKRKMPDLPGAVDE 360 QPSSYFVQFPQAMQRCRDHMIRSLQSVGLKPIIPQGSYFLITDISDFKRKMPDLPGAVDE Sbjct: 301 QPSSYFVQFPQAMQRCRDHMIRSLQSVGLKPIIPQGSYFLITDISDFKRKMPDLPGAVDE 360 Query: 361 PYDRRFVKWMIKNKGLVAIPVSIFYSVPHQKHFDHYIRFCFVKDEATLQAMDEKLRKWKV 420 PYDRRFVKWMIKNKGLVAIPVSIFYSVPHQKHFDHYIRFCFVKDEATLQAMDEKLRKWKV Sbjct: 361 PYDRRFVKWMIKNKGLVAIPVSIFYSVPHQKHFDHYIRFCFVKDEATLQAMDEKLRKWKV 420 Query: 421 EL 422 EL Sbjct: 421 EL 422 >3FVS-A nrPDB Length = 422 Score = 554 bits (1428), Expect = e-158, Method: Composition-based stats. Identities = 422/422 (100%), Positives = 422/422 (100%) Query: 1 MAKQLQARRLDGIDYNPWVEFVKLASEHDVVNLGQGFPDFPPPDFAVEAFQHAVSGDFML 60 MAKQLQARRLDGIDYNPWVEFVKLASEHDVVNLGQGFPDFPPPDFAVEAFQHAVSGDFML Sbjct: 1 MAKQLQARRLDGIDYNPWVEFVKLASEHDVVNLGQGFPDFPPPDFAVEAFQHAVSGDFML 60 Query: 61 NQYTKTFGYPPLTKILASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVII 120 NQYTKTFGYPPLTKILASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVII Sbjct: 61 NQYTKTFGYPPLTKILASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVII 120 Query: 121 IEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVL 180 IEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVL Sbjct: 121 IEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVL 180 Query: 181 NTPNNPLGKVFSREELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTL 240 NTPNNPLGKVFSREELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTL Sbjct: 181 NTPNNPLGKVFSREELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTL 240 Query: 241 TIGSAGKTFSATGWKVGWVLGPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFR 300 TIGSAGKTFSATGWKVGWVLGPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFR Sbjct: 241 TIGSAGKTFSATGWKVGWVLGPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFR 300 Query: 301 QPSSYFVQFPQAMQRCRDHMIRSLQSVGLKPIIPQGSYFLITDISDFKRKMPDLPGAVDE 360 QPSSYFVQFPQAMQRCRDHMIRSLQSVGLKPIIPQGSYFLITDISDFKRKMPDLPGAVDE Sbjct: 301 QPSSYFVQFPQAMQRCRDHMIRSLQSVGLKPIIPQGSYFLITDISDFKRKMPDLPGAVDE 360 Query: 361 PYDRRFVKWMIKNKGLVAIPVSIFYSVPHQKHFDHYIRFCFVKDEATLQAMDEKLRKWKV 420 PYDRRFVKWMIKNKGLVAIPVSIFYSVPHQKHFDHYIRFCFVKDEATLQAMDEKLRKWKV Sbjct: 361 PYDRRFVKWMIKNKGLVAIPVSIFYSVPHQKHFDHYIRFCFVKDEATLQAMDEKLRKWKV 420 Query: 421 EL 422 EL Sbjct: 421 EL 422 >2ZJG-A nrPDB Length = 410 Score = 455 bits (1170), Expect = e-128, Method: Composition-based stats. Identities = 221/414 (53%), Positives = 292/414 (70%), Gaps = 4/414 (0%) Query: 6 QARRLDGIDYNPWVEFVKLASEHDVVNLGQGFPDFPPPDFAVEAFQHAVSGDFMLNQYTK 65 A+R++G+D N WVEF KLA++ VVNLGQGFPD PP + E A D M NQYT+ Sbjct: 1 NAKRIEGLDSNVWVEFTKLAADPSVVNLGQGFPDISPPSYVKEELSKAAFIDNM-NQYTR 59 Query: 66 TFGYPPLTKILASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFF 125 FG+P L K L+ +G++ ++IDP +LV VG YG+LF + Q LVD GDEVII+ PF+ Sbjct: 60 GFGHPALVKALSCLYGKIYQRQIDPNEEILVAVGAYGSLFNSIQGLVDPGDEVIIMVPFY 119 Query: 126 DCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNN 185 DCYEPM MAG PVF+ L+ P +G +SS+W DP EL KF+S+TKA++LNTP+N Sbjct: 120 DCYEPMVRMAGAVPVFIPLRSKP-TDGMKWTSSDWTFDPRELESKFSSKTKAIILNTPHN 178 Query: 186 PLGKVFSREELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTIGSA 245 PLGKV++R+EL+++A LC +HD +CI+DEVY+W+VY GH H+ IA+LPGMWERT+TIGSA Sbjct: 179 PLGKVYTRQELQVIADLCVKHDTLCISDEVYEWLVYTGHTHVKIATLPGMWERTITIGSA 238 Query: 246 GKTFSATGWKVGWVLGPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSY 305 GKTFS TGWK+GW +GP H++KHL+TV QNS + C T QAA+AE+F + P Y Sbjct: 239 GKTFSVTGWKLGWSIGPAHLIKHLQTVQQNSFYTCATPLQAALAEAFWIDIKRMDDPECY 298 Query: 306 FVQFPQAMQRCRDHMIRSLQSVGLKPIIPQGSYFLITDISDFKRKMPDLPGAVDEPYDRR 365 F P+ ++ RD M+R L SVGLKPI+P G YF+I D+S + D+ DEPYD + Sbjct: 299 FNSLPKELEVKRDRMVRLLNSVGLKPIVPDGGYFIIADVSSLGADLSDMNS--DEPYDYK 356 Query: 366 FVKWMIKNKGLVAIPVSIFYSVPHQKHFDHYIRFCFVKDEATLQAMDEKLRKWK 419 FVKWM K+K L AIPVS F + HF+ +RFCF+K ++TL A +E R W Sbjct: 357 FVKWMTKHKKLTAIPVSAFCDSKSKPHFEKLVRFCFIKKDSTLDAAEEIFRAWN 410 >1YIY-A nrPDB Length = 429 Score = 416 bits (1068), Expect = e-116, Method: Composition-based stats. Identities = 200/413 (48%), Positives = 270/413 (65%), Gaps = 4/413 (0%) Query: 8 RRLDGIDYNPWVEFVKLASEHDVVNLGQGFPDFPPPDFAVEAFQHAV-SGDFMLNQYTKT 66 +R G + WVE+++LA+++ +NLGQGFPD+ P +A+ A A S D + NQYT+ Sbjct: 17 KRYQGSTKSVWVEYIQLAAQYKPLNLGQGFPDYHAPKYALNALAAAANSPDPLANQYTRG 76 Query: 67 FGYPPLTKILASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFD 126 FG+P L + L+ + +L+ + I+P+ VLVTVG Y AL+ Q VDEGDEVIIIEPFFD Sbjct: 77 FGHPRLVQALSKLYSQLVDRTINPMTEVLVTVGAYEALYATIQGHVDEGDEVIIIEPFFD 136 Query: 127 CYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNP 186 CYEPM AGG P F+ LKP G SS++W LD EL F +TK +++NTP+NP Sbjct: 137 CYEPMVKAAGGIPRFIPLKPNK--TGGTISSADWVLDNNELEALFNEKTKMIIINTPHNP 194 Query: 187 LGKVFSREELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTIGSAG 246 LGKV R ELE+VA+LC++ +V+C++DEVY+ MV++ +HI I +LPGMWERT+TIGSAG Sbjct: 195 LGKVMDRAELEVVANLCKKWNVLCVSDEVYEHMVFEPFEHIRICTLPGMWERTITIGSAG 254 Query: 247 KTFSATGWKVGWVLGPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYF 306 KTFS TGWK+GW GP+ ++K+L+ VHQN V+ C T Q A+A FE E + P YF Sbjct: 255 KTFSLTGWKIGWAYGPEALLKNLQMVHQNCVYTCATPIQEAIAVGFETELKRLKSPECYF 314 Query: 307 VQFPQAMQRCRDHMIRSLQSVGLKPIIPQGSYFLITDISDFKRKMPDLPGAVDEPYDRRF 366 + RD+M L VG+ P +PQG YF++ D S K+ DL D D RF Sbjct: 315 NSISGELMAKRDYMASFLAEVGMNPTVPQGGYFMVADWSSLDSKV-DLTQETDARKDYRF 373 Query: 367 VKWMIKNKGLVAIPVSIFYSVPHQKHFDHYIRFCFVKDEATLQAMDEKLRKWK 419 KWM K+ GL IP S FYS P++ + ++R+CF K + LQ E LRKWK Sbjct: 374 TKWMTKSVGLQGIPPSAFYSEPNKHLGEDFVRYCFFKKDENLQKAAEILRKWK 426 >1GDE-A nrPDB Length = 389 Score = 371 bits (952), Expect = e-103, Method: Composition-based stats. Identities = 114/411 (27%), Positives = 193/411 (46%), Gaps = 38/411 (9%) Query: 11 DGIDYNPWVEFVKL----ASEHDVVNLGQGFPDFPPPDFAVEAFQHAVSGDFMLNQYTKT 66 D ++ E KL A DV++LG G PDF P E + A+ L Y Sbjct: 5 DRLELVSASEIRKLFDIAAGMKDVISLGIGEPDFDTPQHIKEYAKEALDKG--LTHYGPN 62 Query: 67 FGYPPLTKILASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFD 126 G L + +A + G E DP ++V +G A A + +G+EV+I P F Sbjct: 63 IGLLELREAIAEKLKKQNGIEADPKTEIMVLLGANQAFLMGLSAFLKDGEEVLIPTPAFV 122 Query: 127 CYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNP 186 Y P ++AGG+PV V ++L+ EL T +T+AL++N+P NP Sbjct: 123 SYAPAVILAGGKPVEVP----------TYEEDEFRLNVDELKKYVTDKTRALIINSPCNP 172 Query: 187 LGKVFSREELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTIGSAG 246 G V ++++LE +A +HD++ I+DEVY+ +YD +H SIASL GM+ERT+T+ Sbjct: 173 TGAVLTKKDLEEIADFVVEHDLIVISDEVYEHFIYDDARHYSIASLDGMFERTITVNGFS 232 Query: 247 KTFSATGWKVGWVLGPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYF 306 KTF+ TGW++G+V P I++ + + T Q A A++ + E+ Sbjct: 233 KTFAMTGWRLGFVAAPSWIIERMVKFQMYNATCPVTFIQYAAAKALKDERSW-----KAV 287 Query: 307 VQFPQAMQRCRDHMIRSLQSVGLKPIIPQGSYFLITDISDFKRKMPDLPGAVDEPYDRRF 366 + + R R + + L +GL + P+G++++ I D ++F Sbjct: 288 EEMRKEYDRRRKLVWKRLNEMGLPTVKPKGAFYIFPRIRDTG------------LTSKKF 335 Query: 367 VKWMIKNKGLVAIPVSIFYSVPHQKHFDHYIRFCFVKDEATLQAMDEKLRK 417 + M+K + +P S F K + Y+R + L+ +++ + Sbjct: 336 SELMLKEARVAVVPGSAFG-----KAGEGYVRISYATAYEKLEEAMDRMER 381 >1U08-A nrPDB Length = 386 Score = 357 bits (917), Expect = 4e-99, Method: Composition-based stats. Identities = 127/414 (30%), Positives = 203/414 (49%), Gaps = 34/414 (8%) Query: 5 LQARRLDGIDYNPWVEFVKLASEHDVVNLGQGFPDFPPPDFAVEAFQHAVSGDFMLNQYT 64 + +L + + + LA +H +NL QGFPDF P + E H V+ NQY Sbjct: 7 IPQSKLPQLGTTIFTQMSALAQQHQAINLSQGFPDFDGPRYLQERLAHHVAQG--ANQYA 64 Query: 65 KTFGYPPLTKILASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPF 124 G L + +A L G + D ++ VT G AL+ A ALV GDEVI +P Sbjct: 65 PMTGVQALREAIAQKTERLYGYQPDADSDITVTAGATEALYAAITALVRNGDEVICFDPS 124 Query: 125 FDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPN 184 +D Y P ++GG ++L+P ++++D E A + RT+ ++LNTP+ Sbjct: 125 YDSYAPAIALSGGIVKRMALQP-----------PHFRVDWQEFAALLSERTRLVILNTPH 173 Query: 185 NPLGKVFSREELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTIGS 244 NP V+ + + + H++ I+DEVY+ + + H S+ + P + ER + + S Sbjct: 174 NPSATVWQQADFAALWQAIAGHEIFVISDEVYEHINFSQQGHASVLAHPQLRERAVAVSS 233 Query: 245 AGKTFSATGWKVGWVLGPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSS 304 GKT+ TGWKVG+ + P I +R VHQ F T +Q A+A+ R Sbjct: 234 FGKTYHMTGWKVGYCVAPAPISAEIRKVHQYLTFSVNTPAQLALADML-------RAEPE 286 Query: 305 YFVQFPQAMQRCRDHMIRSLQSVGLKPIIPQGSYFLITDISDFKRKMPDLPGAVDEPYDR 364 +++ P ++ RD ++ +L L+ + +G+YFL+ D S AV D Sbjct: 287 HYLALPDFYRQKRDILVNALNESRLEILPCEGTYFLLVDYS-----------AVSTLDDV 335 Query: 365 RFVKWMIKNKGLVAIPVSIFYSVPHQKHFDHYIRFCFVKDEATLQAMDEKLRKW 418 F +W+ + G+ AIP+S+F + P IR CF K E+TL A E+LR+ Sbjct: 336 EFCQWLTQEHGVAAIPLSVFCADPFP---HKLIRLCFAKKESTLLAAAERLRQL 386 >6F77-B nrPDB Length = 400 Score = 349 bits (896), Expect = 1e-96, Method: Composition-based stats. Identities = 106/398 (26%), Positives = 184/398 (46%), Gaps = 32/398 (8%) Query: 24 LASEHDVVNLGQGFPDFPPPDFAVEAFQHAVSGDFMLNQYTKTFGYPPLTKILASFFGEL 83 A DV+ LG G PDF PD +A A+ D +YT G P L + +A F Sbjct: 27 KAKGRDVIGLGAGEPDFDTPDNIKKAAIDAI--DRGETKYTPVSGIPELREAIAKKFKRE 84 Query: 84 LGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVS 143 + + ++ T GG LF AF A ++ GDEV+I P++ Y M + GG PVFV Sbjct: 85 NNLDYTAAQTIVGT-GGKQILFNAFMATLNPGDEVVIPAPYWVSYPEMVALCGGTPVFVP 143 Query: 144 LKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASLC 203 + +N++L +L T +TK V N+P+NP G +S EEL+ + + Sbjct: 144 TR----------QENNFKLKAEDLDRAITPKTKWFVFNSPSNPSGAAYSHEELKALTDVL 193 Query: 204 QQH-DVVCITDEVYQWMVYDGHQH-ISIASLPGMWERTLTIGSAGKTFSATGWKVGWVLG 261 +H V +TD++Y+ + Y + + PG++ERTLT+ K ++ TGW++G+ G Sbjct: 194 MKHPHVWVLTDDMYEHLTYGDFRFATPVEVEPGLYERTLTMNGVSKAYAMTGWRIGYAAG 253 Query: 262 PDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFPQAMQRCRDHMI 321 P H++K + + + +Q A E+ P + + + Q RD ++ Sbjct: 254 PLHLIKAMDMIQGQQTSGAASIAQWAAVEAL-------NGPQDFIGRNKEIFQGRRDLVV 306 Query: 322 RSL-QSVGLKPIIPQGSYFLITDISDFKRKMPDLPGAVDEPYDRRFVKWMIKNKGLVAIP 380 L Q+ G+ P+G++++ + K P D FV +++ +G+ + Sbjct: 307 SMLNQAKGISCPTPEGAFYVYPSCAGLIGKTA--PSGKVIETDEDFVSELLETEGVAVVH 364 Query: 381 VSIFYSVPHQKHFDHYIRFCFVKDEATLQAMDEKLRKW 418 S F P+ R + EA L+ +++++ Sbjct: 365 GSAFGLGPN-------FRISYATSEALLEEACRRIQRF 395 >6F35-A nrPDB Length = 410 Score = 342 bits (878), Expect = 1e-94, Method: Composition-based stats. Identities = 107/420 (25%), Positives = 191/420 (45%), Gaps = 37/420 (8%) Query: 6 QARRLDGIDYNPWVEFVKLAS-----EHDVVNLGQGFPDFPPPDFAVEAFQHAVSGDFML 60 A R+ I + ++ A+ V+ LG G PDF P+ +A A+ Sbjct: 14 PASRISSIGVSEILKIGARAAAMKREGKPVIILGAGEPDFDTPEHVKQAASDAIHRGE-- 71 Query: 61 NQYTKTFGYPPLTKILASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVII 120 +YT G P L K + F G + L + V G LF A A +D GDEVII Sbjct: 72 TKYTALDGTPELKKAIREKFQRENGLAYE-LDEITVATGAKQILFNAMMASLDPGDEVII 130 Query: 121 IEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVL 180 P++ Y + + G+PV ++ +SS ++L +L T RT+ ++L Sbjct: 131 PTPYWTSYSDIVHICEGKPVLIACD----------ASSGFRLTAEKLEAAITPRTRWVLL 180 Query: 181 NTPNNPLGKVFSREELELVASLCQQH-DVVCITDEVYQWMVYDGHQHISIASL-PGMWER 238 N+P+NP G +S + + + +H V + D++Y+ +VYDG + ++ A L PG+ R Sbjct: 181 NSPSNPSGAAYSAADYRPLLEVLLRHPHVWLLVDDMYEHIVYDGFRFVTPAQLEPGLKNR 240 Query: 239 TLTIGSAGKTFSATGWKVGWVLGPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLL 298 TLT+ K ++ TGW++G+ GP ++K + V + + SQAA + Sbjct: 241 TLTVNGVSKAYAMTGWRIGYAGGPRELIKAMAVVQSQATSCPSSISQAASVVAL------ 294 Query: 299 FRQPSSYFVQFPQAMQRCRDHMIRSLQSV-GLKPIIPQGSYFLITDISDFKRKMPDLPGA 357 P + + ++ QR RD ++ L ++ GL +P+G+++ + + K+ P Sbjct: 295 -NGPQDFLKERTESFQRRRDLVVNGLNAIDGLDCRVPEGAFYTFSGCAGVLGKVT--PSG 351 Query: 358 VDEPYDRRFVKWMIKNKGLVAIPVSIFYSVPHQKHFDHYIRFCFVKDEATLQAMDEKLRK 417 D F +++++ + +P S F P + R + EA L+ E++ Sbjct: 352 KRIKTDTDFCAYLLEDAHVAVVPGSAFGLSP-------FFRISYATSEAELKEALERIAA 404 >2X5D-A nrPDB Length = 412 Score = 341 bits (875), Expect = 3e-94, Method: Composition-based stats. Identities = 94/425 (22%), Positives = 180/425 (42%), Gaps = 41/425 (9%) Query: 1 MAKQLQARRLDGIDYNPWVEF-----VKLASEH---DVVNLGQGFPDFPPPDFAVEAFQH 52 MA+ ARR ID P F +K+A+ D+++L G PD P P VE Sbjct: 2 MAESRPARRFARIDRLPPYVFNITAELKMAARRRGEDIIDLSMGNPDGPTPPHIVEKL-C 60 Query: 53 AVSGDFMLNQYTKTFGYPPLTKILASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQALV 112 V+ + Y+ + G P L + ++ ++ + +IDP +VT+G L A + Sbjct: 61 TVAQREDTHGYSTSRGIPRLRRAISHWYRDRYDVQIDPESEAIVTIGSKEGLAHLMLATL 120 Query: 113 DEGDEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFT 172 D GD +++ P + + ++AG + V L PG EL + + Sbjct: 121 DHGDTILVPNPSYPIHIYGAVIAGAQVRSVPLVPGIDFFNELERAIRESI---------- 170 Query: 173 SRTKALVLNTPNNPLGKVFSREELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASL 232 + + ++L P+NP + + E V +L +Q+DV+ + D Y +VYDG + SI + Sbjct: 171 PKPRMMILGFPSNPTAQCVELDFFERVVALAKQYDVMVVHDLAYADIVYDGWKAPSIMQV 230 Query: 233 PGMWERTLTIGSAGKTFSATGWKVGWVLGPDHIMKHLRTVHQNSVFHCPTQSQAAVAESF 292 PG + + + K+++ GW++G+++G ++ L + + T Q A + Sbjct: 231 PGAKDIAVEFFTLSKSYNMAGWRIGFMVGNPELVSALARIKSYHDYGTFTPLQVAAIAAL 290 Query: 293 EREQLLFRQPSSYFVQFPQAMQRCRDHMIRSLQSVGLKPIIPQGSYFLITDISDFKRKMP 352 E +Q R + Q+ RD +++ L+ G P+ S ++ I Sbjct: 291 EGDQQCVRD-------IARQYQQRRDVLVKGLREAGWMVENPKASMYVWAKI-------- 335 Query: 353 DLPGAVDEPYDRRFVKWMIKNKGLVAIPVSIFYSVPHQKHFDHYIRFCFVKDEATLQAMD 412 P F K ++++ + P F + D ++RF +++ L+ Sbjct: 336 --PEPYAHLGSLEFAKKLLQDAKVSVSPGIGFGD-----YGDDHVRFALIENRDRLRQAV 388 Query: 413 EKLRK 417 ++ Sbjct: 389 RGIKA 393 >1J32-A nrPDB Length = 388 Score = 341 bits (875), Expect = 3e-94, Method: Composition-based stats. Identities = 105/397 (26%), Positives = 184/397 (46%), Gaps = 41/397 (10%) Query: 24 LASEHDVVNLGQGFPDFPPPDFAVEAFQHAVSGDFMLNQYTKTFGYPPLTKILASFFGEL 83 A DV + G PDF P VEA + A+ +Y G P L + +A Sbjct: 26 KAEGIDVCSFSAGEPDFNTPKHIVEAAKAALEQGK--TRYGPAAGEPRLREAIAQKLQRD 83 Query: 84 LGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVS 143 G N+LVT GG ++F A+++ GDEVII PF+ Y M +A G PV + Sbjct: 84 NGLCYGA-DNILVTNGGKQSIFNLMLAMIEPGDEVIIPAPFWVSYPEMVKLAEGTPVILP 142 Query: 144 LKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASLC 203 + +++ P ++ T +TK LV NTP+NP G V++ +E+ +A + Sbjct: 143 ----------TTVETQFKVSPEQIRQAITPKTKLLVFNTPSNPTGMVYTPDEVRAIAQVA 192 Query: 204 QQHDVVCITDEVYQWMVYDGHQHISI-ASLPGMWERTLTIGSAGKTFSATGWKVGWVLGP 262 + + ++DE+Y+ ++YD QH+SI A+ P +ER++ KT++ TGW+VG++ GP Sbjct: 193 VEAGLWVLSDEIYEKILYDDAQHLSIGAASPEAYERSVVCSGFAKTYAMTGWRVGFLAGP 252 Query: 263 DHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFPQAMQRCRDHMIR 322 ++K + +S + T +Q ++E Q + + A R +M+ Sbjct: 253 VPLVKAATKIQGHSTSNVCTFAQYGAIAAYENSQDCVQ-------EMLAAFAERRRYMLD 305 Query: 323 SLQSV-GLKPIIPQGSYFLITDISDFKRKMPDLPGAVDEPYDRRFVKWMIKNKGLVAIPV 381 +L ++ GL+ P G++++ I+ R D F ++ + +P Sbjct: 306 ALNAMPGLECPKPDGAFYMFPSIAKTGRSSLD------------FCSELLDQHQVATVPG 353 Query: 382 SIFYSVPHQKHFDHYIRFCFVKDEATLQAMDEKLRKW 418 + F + D IR + D T++ E+L K+ Sbjct: 354 AAFGA-------DDCIRLSYATDLDTIKRGMERLEKF 383 >1GC4-A nrPDB Length = 385 Score = 341 bits (873), Expect = 4e-94, Method: Composition-based stats. Identities = 120/416 (28%), Positives = 197/416 (47%), Gaps = 45/416 (10%) Query: 7 ARRLDGIDYNPWVEFVKLA-----SEHDVVNLGQGFPDFPPPDFAVEAFQHAVSGDFMLN 61 +RR+ + + V A D+V L G PDF P+ EA + A++ Sbjct: 5 SRRVQAMKPDAVVAVNAKALELRRQGVDLVALTAGEPDFDTPEHVKEAARRALAQGK--T 62 Query: 62 QYTKTFGYPPLTKILASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVIII 121 +Y G P L + LA F G + P + VTVGG ALF FQA++D GDEVI++ Sbjct: 63 KYAPPAGIPELREALAEKFRRENGLSVTPEETI-VTVGGSQALFNLFQAILDPGDEVIVL 121 Query: 122 EPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLN 181 P++ Y M AGG V V P + DP + T RTKALV+N Sbjct: 122 SPYWVSYPEMVRFAGGVVVEVETLP----------EEGFVPDPERVRRAITPRTKALVVN 171 Query: 182 TPNNPLGKVFSREELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTLT 241 +PNNP G V+ +E LE +A L +HD ++DE+Y+ ++Y+G P E TLT Sbjct: 172 SPNNPTGAVYPKEVLEALARLAVEHDFYLVSDEIYEHLLYEGEHFSPGRVAP---EHTLT 228 Query: 242 IGSAGKTFSATGWKVGWVLGPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQ 301 + A K F+ TGW++G+ GP ++K + +V + S T +Q A E+ ++ Sbjct: 229 VNGAAKAFAMTGWRIGYACGPKEVIKAMASVSRQSTTSPDTIAQWATLEALTNQE----A 284 Query: 302 PSSYFVQFPQAMQRCRDHMIRSLQSVGLKPIIPQGSYFLITDISDFKRKMPDLPGAVDEP 361 ++ +A +R RD ++ L ++GLK + P G+++++ D S P Sbjct: 285 SRAFVEMAREAYRRRRDLLLEGLTALGLKAVRPSGAFYVLMDTSPIA------------P 332 Query: 362 YDRRFVKWMIKNKGLVAIPVSIFYSVPHQKHFDHYIRFCFVKDEATLQAMDEKLRK 417 + R + +++ G+ +P + F + ++R + E L+ E+ + Sbjct: 333 DEVRAAERLLE-AGVAVVPGTDFAAF-------GHVRLSYATSEENLRKALERFAR 380 >5WMH-A nrPDB Length = 475 Score = 341 bits (873), Expect = 5e-94, Method: Composition-based stats. Identities = 110/390 (28%), Positives = 181/390 (46%), Gaps = 28/390 (7%) Query: 30 VVNLGQGFPDFPPPDFAVEAFQHAVSGDFMLNQYTKTFGYPPLTKILASFFGELLGQEID 89 V+ L G PDF P EA +A+ F +YT G L + + E G Sbjct: 101 VIRLAAGEPDFDTPKVVAEAGINAIREGF--TRYTLNAGITELREAICRKLKEENGLSYA 158 Query: 90 PLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPI 149 P +LV+ G +L A A+ GDEVII P++ Y +A PV + K Sbjct: 159 P-DQILVSNGAKQSLLQAVLAVCSPGDEVIIPAPYWVSYTEQARLADATPVVIPTK---- 213 Query: 150 QNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQQH-DV 208 S+N+ LDP +L K T +++ L+L +P+NP G V+ + LE +A + +H + Sbjct: 214 ------ISNNFLLDPKDLESKLTEKSRLLILCSPSNPTGSVYPKSLLEEIARIIAKHPRL 267 Query: 209 VCITDEVYQWMVYDGHQHISIASLPGMWERTLTIGSAGKTFSATGWKVGWVLGPDHIMKH 268 + ++DE+Y+ ++Y H S ASLP M+ERTLT+ K F+ TGW++G++ GP HI+ Sbjct: 268 LVLSDEIYEHIIYAPATHTSFASLPDMYERTLTVNGFSKAFAMTGWRLGYLAGPKHIVAA 327 Query: 269 LRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFPQAMQRCRDHMIRSLQSV- 327 + + +Q A + L + + +A + RD +++SL + Sbjct: 328 CSKLQGQVSSGASSIAQKAGVAAL----GLGKAGGETVAEMVKAYRERRDFLVKSLGDIK 383 Query: 328 GLKPIIPQGSYFLITDISDFKRKMPDLPGAVDEPYDRRFVKWMIKNKGLVAIPVSIFYSV 387 G+K PQG+++L D S + + G +++ + + + +P F Sbjct: 384 GVKISEPQGAFYLFIDFSAYYGSEAEGFGLIND--SSSLALYFLDKFQVAMVPGDAFGD- 440 Query: 388 PHQKHFDHYIRFCFVKDEATLQAMDEKLRK 417 D IR + LQA EK+RK Sbjct: 441 ------DSCIRISYATSLDVLQAAVEKIRK 464 >3B46-A nrPDB Length = 447 Score = 338 bits (866), Expect = 3e-93, Method: Composition-based stats. Identities = 138/401 (34%), Positives = 211/401 (52%), Gaps = 12/401 (2%) Query: 26 SEHDVVNLGQGFPDFPPPDFAVEAFQHAVSGDFMLNQYTKTFGYPPLTKILASFFGELLG 85 +++NLGQGF + PP FA++ Q A+ M+NQY+ T G P L L + + Sbjct: 55 QGRELINLGQGFFSYSPPQFAIKEAQKALDIP-MVNQYSPTRGRPSLINSLIKLYSPIYN 113 Query: 86 QEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVSLK 145 E+ NV VT G + + L++ GDEVI+ EPFFD Y P + GG+ V+V + Sbjct: 114 TELKA-ENVTVTTGANEGILSCLMGLLNAGDEVIVFEPFFDQYIPNIELCGGKVVYVPIN 172 Query: 146 PGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQQ 205 P + W +D + TS+TKA+++NTP+NP+GKVF+REEL + ++C + Sbjct: 173 PPKELDQRNTRGEEWTIDFEQFEKAITSKTKAVIINTPHNPIGKVFTREELTTLGNICVK 232 Query: 206 HDVVCITDEVYQWMVYDGHQHISIASL-PGMWERTLTIGSAGKTFSATGWKVGWVLG-PD 263 H+VV I+DEVY+ + + IA+L P + + TLT+GSAGK+F+ATGW++GWVL Sbjct: 233 HNVVIISDEVYEHLYFTD-SFTRIATLSPEIGQLTLTVGSAGKSFAATGWRIGWVLSLNA 291 Query: 264 HIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFPQAMQRCRDHMIRS 323 ++ + H F P+ Q A A S + YF + Q Sbjct: 292 ELLSYAAKAHTRICFASPSPLQEACANSINDALKI-----GYFEKMRQEYINKFKIFTSI 346 Query: 324 LQSVGLKPIIPQGSYFLITDISDFKR--KMPDLPGAVDEPYDRRFVKWMIKNKGLVAIPV 381 +GL P+G+YF++ D S K P +++ D R W+I G+VAIP Sbjct: 347 FDELGLPYTAPEGTYFVLVDFSKVKIPEDYPYPEEILNKGKDFRISHWLINELGVVAIPP 406 Query: 382 SIFYSVPHQKHFDHYIRFCFVKDEATLQAMDEKLRKWKVEL 422 + FY H+K ++ +RF KD+A L+ E+L+ K L Sbjct: 407 TEFYIKEHEKAAENLLRFAVCKDDAYLENAVERLKLLKDYL 447 >1O4S-A nrPDB Length = 389 Score = 333 bits (854), Expect = 8e-92, Method: Composition-based stats. Identities = 109/417 (26%), Positives = 189/417 (45%), Gaps = 51/417 (12%) Query: 7 ARRLDGIDYNPWVEFVKLAS-----EHDVVNLGQGFPDFPPPDFAVEAFQHAVSGDFMLN 61 +RR+ I + +E A DV+NL G PDFP P+ VE + + Sbjct: 15 SRRISEIPISKTMELDAKAKALIKKGEDVINLTAGEPDFPTPEPVVEEAVRFLQKGEV-- 72 Query: 62 QYTKTFGYPPLTKILASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVIII 121 +YT G L + +A GE ++I P V+VT G ALF AF AL+D GDEVI+ Sbjct: 73 KYTDPRGIYELREGIAKRIGERYKKDISP-DQVVVTNGAKQALFNAFMALLDPGDEVIVF 131 Query: 122 EPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLN 181 P + Y P ++AGG V E S N+Q E+ G +TKA+++N Sbjct: 132 SPVWVSYIPQIILAGGTVNVV----------ETFMSKNFQPSLEEVEGLLVGKTKAVLIN 181 Query: 182 TPNNPLGKVFSREELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTLT 241 +PNNP G V+ RE LE + L ++ + I+DEVY +VY + SI + ++R + Sbjct: 182 SPNNPTGVVYRREFLEGLVRLAKKRNFYIISDEVYDSLVYTD-EFTSILDVSEGFDRIVY 240 Query: 242 IGSAGKTFSATGWKVGWVLGPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQ 301 I K+ S TGW+VG+++ + + + + ++ T +Q A ++ E + Sbjct: 241 INGFSKSHSMTGWRVGYLISSEKVATAVSKIQSHTTSCINTVAQYAALKALEVDN----- 295 Query: 302 PSSYFVQFPQAMQRCRDHMIRSLQSVGLKPIIPQGSYFLITDISDFKRKMPDLPGAVDEP 361 Q + ++ ++ L+ +G+K + P+G+++L + Sbjct: 296 -----SYMVQTFKERKNFVVERLKKMGVKFVEPEGAFYLFFKVRG--------------- 335 Query: 362 YDRRFVKWMIKNKGLVAIPVSIFYSVPHQKHFDHYIRFCFVKDEATLQAMDEKLRKW 418 D +F + +++ K + +P S F ++R F L +++ + Sbjct: 336 DDVKFCERLLEEKKVALVPGSAFLK-------PGFVRLSFATSIERLTEALDRIEDF 385 >2O0R-A nrPDB Length = 411 Score = 324 bits (831), Expect = 3e-89, Method: Composition-based stats. Identities = 136/418 (32%), Positives = 196/418 (46%), Gaps = 35/418 (8%) Query: 9 RLDGIDYNPWVEFVKLASEHDVVNLGQGFPDFPPPDFAVEAFQHAVSGDFMLNQYTKTFG 68 RL + E LA+ VNLGQGFPD P ++A Q A++G +NQY G Sbjct: 6 RLRPYATTVFAEMSALATRIGAVNLGQGFPDEDGPPKMLQAAQDAIAGG--VNQYPPGPG 63 Query: 69 YPPLTKILASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCY 128 PL + +A+ G + DP VLVTVG A+ A LV+ G EV++IEPF+D Y Sbjct: 64 SAPLRRAIAAQRRRHFGVDYDPETEVLVTVGATEAIAAAVLGLVEPGSEVLLIEPFYDSY 123 Query: 129 EPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLG 188 P+ MAG V V L P + LD L T RT+AL++N+P+NP G Sbjct: 124 SPVVAMAGAHRVTVPLVPDG---------RGFALDADALRRAVTPRTRALIINSPHNPTG 174 Query: 189 KVFSREELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTIGSAGKT 248 V S EL +A + ++V ITDEVY+ +V+D +H+ +A GM ERT+TI SA K Sbjct: 175 AVLSATELAAIAEIAVAANLVVITDEVYEHLVFDHARHLPLAGFDGMAERTITISSAAKM 234 Query: 249 FSATGWKVGWVLGPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQ 308 F+ TGWK+GW GP ++ +R Q + Q AVA + + E ++ Sbjct: 235 FNCTGWKIGWACGPAELIAGVRAAKQYLSYVGGAPFQPAVALALDTE-------DAWVAA 287 Query: 309 FPQAMQRCRDHMIRSLQSVGLKPIIPQGSYFLITDISDFKRKMPDLPGAVDEPYDRRFVK 368 +++ RD + L +G G+YFL D P + F Sbjct: 288 LRNSLRARRDRLAAGLTEIGFAVHDSYGTYFLCAD-----------PRPLGYDDSTEFCA 336 Query: 369 WMIKNKGLVAIPVSIFYS------VPHQKHFDHYIRFCFVKDEATLQAMDEKLRKWKV 420 + + G+ AIP+S F ++H +RF F K + TL +L Sbjct: 337 ALPEKVGVAAIPMSAFCDPAAGQASQQADVWNHLVRFTFCKRDDTLDEAIRRLSVLAE 394 >4MY5-A nrPDB Length = 393 Score = 310 bits (795), Expect = 5e-85, Method: Composition-based stats. Identities = 100/418 (23%), Positives = 189/418 (45%), Gaps = 42/418 (10%) Query: 8 RRLDGIDYNPWVEFVKLASE-HDVVNLGQGFPDFPPPDFAVEAFQHAVSGDFMLNQYTKT 66 + L+ I+ + +F + S+ DV+ L G PDF P EA + A+ D + YT Sbjct: 11 KNLNKIEVSMIRQFDQSISDIPDVLKLTLGEPDFATPKHIKEAAKRAIDADE--SHYTGM 68 Query: 67 FGYPPLTKILASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFD 126 G L + ++F E +P +LVT+G AL + A+++ GD+V++ P + Sbjct: 69 AGLLALRQAASAFVKEKYHLTYNPDNEILVTIGATEALSASLTAILEPGDKVLLPAPAYP 128 Query: 127 CYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKF---TSRTKALVLNTP 183 YEP+ + G V + + S+++ L P L KA++LN P Sbjct: 129 GYEPVVNLVGAEVVEIDTR-----------SNDFVLTPEMLEEAILKEGEALKAVILNYP 177 Query: 184 NNPLGKVFSREELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTIG 243 NP G +SR++++ +A + +++ + I+DEVY + Y G H+SIA ++T+ I Sbjct: 178 TNPTGVTYSRQQIKNLAEVLKKYPIFVISDEVYAELTYTGESHVSIAEYLP--DQTILIS 235 Query: 244 SAGKTFSATGWKVGWVLGPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPS 303 K+ + TGW++G + P + L HQ V T Q A E+ Sbjct: 236 GLSKSHAMTGWRLGLIFAPAVLTAQLIKSHQYLVTAATTSVQFAAIEALTN-------GK 288 Query: 304 SYFVQFPQAMQRCRDHMIRSLQSVGLKPIIPQGSYFLITDISDFKRKMPDLPGAVDEPYD 363 + + + RD++I ++++ K I P G++++ I + + Sbjct: 289 DDALPMKEEYIKRRDYIIEKMEAMKFKIIKPDGAFYIFAKIPVAQGQ-----------DS 337 Query: 364 RRFVKWMIKNKGLVAIPVSIFYSVPHQKHFDHYIRFCFVKDEATLQAMDEKLRKWKVE 421 +F++ K K + IP F K+ + Y+R + T++ ++L+++ + Sbjct: 338 FKFLQDFAKEKAVAFIPGVAFG-----KYGEGYLRISYAASMETIKEAMKRLKEFMEQ 390 >2Z61-A nrPDB Length = 370 Score = 310 bits (795), Expect = 5e-85, Method: Composition-based stats. Identities = 95/414 (22%), Positives = 180/414 (43%), Gaps = 53/414 (12%) Query: 5 LQARRLDGIDYNPWVEFVKLASEHDVVNLGQGFPDFPPPDFAVEAFQHAVSGDFMLNQYT 64 L + +D + ++ + V++L G PDF P V+ ++ YT Sbjct: 7 LNFESFEVMDILALAQKLE-SEGKKVIHLEIGEPDFNTPKPIVDEGIKSLKEGK--THYT 63 Query: 65 KTFGYPPLTKILASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPF 124 + G L + ++ + + +I P N+++T G LF A +++D+GDEV+I P Sbjct: 64 DSRGILELREKISELYKDKYKADIIP-DNIIITGGSSLGLFFALSSIIDDGDEVLIQNPC 122 Query: 125 FDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPN 184 + CY+ G +PVF L + +TKA+++N+P+ Sbjct: 123 YPCYKNFIRFLGAKPVFCD------------------FTVESLEEALSDKTKAIIINSPS 164 Query: 185 NPLGKVFSREELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTIGS 244 NPLG+V RE + ++ I+DE+Y +VY+G + +I E+T+ I Sbjct: 165 NPLGEVIDRE----IYEFAYENIPYIISDEIYNGLVYEGKCYSAI-EFDENLEKTILING 219 Query: 245 AGKTFSATGWKVGWVLGPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSS 304 K ++ TGW++G+V+ D I++ + + QN PT SQ A ++FE+E Sbjct: 220 FSKLYAMTGWRIGYVISNDEIIEAILKLQQNLFISAPTISQYAALKAFEKE------TER 273 Query: 305 YFVQFPQAMQRCRDHMIRSLQSVGLKPIIPQGSYFLITDISDFKRKMPDLPGAVDEPYDR 364 + R R +++ ++ G + P G+Y++ +I + R Sbjct: 274 EINSMIKEFDRRRRLVLKYVKDFGWEVNNPIGAYYVFPNIGEDGR--------------- 318 Query: 365 RFVKWMIKNKGLVAIPVSIFYSVPHQKHFDHYIRFCFVKDEATLQAMDEKLRKW 418 F ++K K + P F S +YIR + ++ E+++++ Sbjct: 319 EFAYKLLKEKFVALTPGIGFGS-----KGKNYIRISYANSYENIKEGLERIKEF 367 >1V2E-A nrPDB Length = 381 Score = 307 bits (785), Expect = 8e-84, Method: Composition-based stats. Identities = 136/409 (33%), Positives = 195/409 (47%), Gaps = 48/409 (11%) Query: 9 RLDGIDYNPWVEFVKLASEHDVVNLGQGFPDFPPPDFAVEAFQHAVSGDFMLNQYTKTFG 68 R + + + LA VNLGQGFP PPP F +EA + A+ +QY G Sbjct: 6 RTEAAKESIFPRMSGLAQRLGAVNLGQGFPSNPPPPFLLEAVRRALGRQ---DQYAPPAG 62 Query: 69 YPPLTKILASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCY 128 P L + LA F ++P V+VT G AL+ Q+LV GDEV+++EPFFD Y Sbjct: 63 LPALREALAEEFA------VEPES-VVVTSGATEALYVLLQSLVGPGDEVVVLEPFFDVY 115 Query: 129 EPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLG 188 P +AG + V L P ++LD L T RT+AL+LNTP NP G Sbjct: 116 LPDAFLAGAKARLVRLDLTP---------EGFRLDLSALEKALTPRTRALLLNTPMNPTG 166 Query: 189 KVFSREELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTIGSAGKT 248 VF ELE +A L + HD+ I+DEVY + Y P ERT T+GSAGK Sbjct: 167 LVFGERELEAIARLARAHDLFLISDEVYDELYYGERPRRLREFAP---ERTFTVGSAGKR 223 Query: 249 FSATGWKVGWVLGPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQ 308 ATG++VGW++GP M L + Q + F PT QA VAE+ + + ++ Sbjct: 224 LEATGYRVGWIVGPKEFMPRLAGMRQWTSFSAPTPLQAGVAEALK-----LARREGFYEA 278 Query: 309 FPQAMQRCRDHMIRSLQSVGLKPIIPQGSYFLITDISDFKRKMPDLPGAVDEPYDRRFVK 368 + +R RD + L+++GL+ +P+G+YFL+ ++ + Sbjct: 279 LREGYRRRRDLLAGGLRAMGLRVYVPEGTYFLMAELPGWD------------------AF 320 Query: 369 WMIKNKGLVAIPVSIFYSVPHQKHFDHYIRFCFVKDEATLQAMDEKLRK 417 +++ + IP S FY K RF F K E L E+L + Sbjct: 321 RLVEEARVALIPASAFYLEDPPK---DLFRFAFCKTEEELHLALERLGR 366 >5YHV-A nrPDB Length = 394 Score = 292 bits (748), Expect = 1e-79, Method: Composition-based stats. Identities = 94/404 (23%), Positives = 157/404 (38%), Gaps = 40/404 (9%) Query: 17 PWVEFVKLASEH-DVVNLGQGFPDFPPPDFAVEAFQHAVSGDFMLNQYTKTFGYPPLTKI 75 W+ + H D+VNL G P P+ A A+ + + Y+ G P L Sbjct: 25 VWLAAAERQRTHGDLVNLSAGQPSAGAPEPVRAAAAAALHLNQL--GYSVALGIPELRDA 82 Query: 76 LASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMA 135 +A+ + G ++P V++T G G AF A D GD V + P + CY + Sbjct: 83 IAADYQRRHGITVEP-DAVVITTGSSGGFLLAFLACFDAGDRVAMASPGYPCYRNILSAL 141 Query: 136 GGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREE 195 G V + G + +Q LA + +V+ +P NP G V EE Sbjct: 142 GCEVVEIPC----------GPQTRFQPTAQMLAE-IDPPLRGVVVASPANPTGTVIPPEE 190 Query: 196 LELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTIGSAGKTFSATGWK 255 L +AS C DV I+DEVY +VY G S A + + S K ++ TGW+ Sbjct: 191 LAAIASWCDASDVRLISDEVYHGLVYQGAPQTSCAW--QTSRNAVVVNSFSKYYAMTGWR 248 Query: 256 VGWVLGPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFPQAMQR 315 +GW+L P + + + + N P SQ A +F E + + Sbjct: 249 LGWLLVPTVLRRAVDCLTGNFTICPPVLSQIAAVSAFTPEATAEADGN------LASYAI 302 Query: 316 CRDHMIRSLQSVGLKPIIP-QGSYFLITDISDFKRKMPDLPGAVDEPYDRRFVKWMIKNK 374 R ++ L+ +G+ + P G++++ D+SDF F ++ + Sbjct: 303 NRSLLLDGLRRIGIDRLAPTDGAFYVYADVSDFTSD------------SLAFCSKLLADT 350 Query: 375 GLVAIPVSIFYSVPHQKHFDHYIRFCFVKDEATLQAMDEKLRKW 418 G+ P F ++R F ++ ++ W Sbjct: 351 GVAIAPGIDF----DTARGGSFVRISFAGPSGDIEEALRRIGSW 390 >1XI9-A nrPDB Length = 406 Score = 292 bits (746), Expect = 2e-79, Method: Composition-based stats. Identities = 99/405 (24%), Positives = 175/405 (43%), Gaps = 47/405 (11%) Query: 26 SEHDVVNLGQGFP---DFPPPDFAVEAFQHAVSGDFMLNQYTKTFGYPPLTKILASFFGE 82 V+ L G P DF PP+ EA+ A+ N Y + G P L K + Sbjct: 36 KGIKVIRLNIGDPVKFDFQPPEHMKEAYCKAIKEGH--NYYGDSEGLPELRKAIVEREKR 93 Query: 83 LLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPVFV 142 G +I P +V VT AL F AL+D GDE+++ P + Y + GG+PV Sbjct: 94 KNGVDITP-DDVRVTAAVTEALQLIFGALLDPGDEILVPGPSYPPYTGLVKFYGGKPVEY 152 Query: 143 SLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASL 202 +WQ D ++ K T RTKA+ + PNNP G ++ ++ LE + ++ Sbjct: 153 ----------RTIEEEDWQPDIDDIRKKITDRTKAIAVINPNNPTGALYDKKTLEEILNI 202 Query: 203 CQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTIGSAGKTFSATGWKVGWV--L 260 ++++ I+DE+Y M Y+G +HIS SL + + K + ATGW++G++ + Sbjct: 203 AGEYEIPVISDEIYDLMTYEG-EHISPGSLTKDVP-VIVMNGLSKVYFATGWRLGYMYFV 260 Query: 261 GPDHIMKHLRTVHQNSV---FHCPTQSQAAVAESFEREQLLFRQPSSYFVQFPQAMQRCR 317 P++ + +R T +Q A P Y ++ + ++ R Sbjct: 261 DPENKLSEVREAIDRLARIRLCPNTPAQFAAIAGLT-------GPMDYLKEYMKKLKERR 313 Query: 318 DHMIRSLQSV-GLKPIIPQGSYFLITDISDFKRKMPDLPGAVDEPYDRRFVKWMIKNKGL 376 D++ + L + G+ PQG++++ I K D+ FV ++ N + Sbjct: 314 DYIYKRLNEIPGISTTKPQGAFYIFPKIEVGPWK-----------NDKEFVLDVLHNAHV 362 Query: 377 VAIPVSIFYSVPHQKHFDHYIRFCFVKDEATLQAMDEKLRKWKVE 421 + + S F ++ + R F+ L+ ++ K+ E Sbjct: 363 LFVHGSGFG-----EYGAGHFRAVFLPPIEILEEAMDRFEKFMKE 402 >3PDX-A nrPDB Length = 402 Score = 278 bits (710), Expect = 3e-75, Method: Composition-based stats. Identities = 88/409 (21%), Positives = 170/409 (41%), Gaps = 48/409 (11%) Query: 22 VKLASEHDVVNLGQGFP----DFPPPDFAVEAFQHAVSGDFMLNQYTKTFGYPPLTKILA 77 VK V++L G P + P +A + A+ N Y + GY + +A Sbjct: 25 VKPNPNKTVISLSIGDPTVFGNLPTDPEVTQAMKDALDSGK-YNGYAPSIGYLSSREEVA 83 Query: 78 SFFGELLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGG 137 S++ + ++V++T G A+ L + G ++I P F Y + G Sbjct: 84 SYY--HCPEAPLEAKDVILTSGCSQAIELCLAVLANPGQNILIPRPGFSLYRTLAESMGI 141 Query: 138 RPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELE 197 +L P +W++D +L +T LV+N P+NP G VFS+ L+ Sbjct: 142 EVKLYNLLP----------EKSWEIDLKQLESLIDEKTACLVVNNPSNPCGSVFSKRHLQ 191 Query: 198 LVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTIGSAGKTFSATGWKVG 257 + ++ ++ V + DE+Y MV+ ++ +A+L L+ G K + GW++G Sbjct: 192 KILAVAERQCVPILADEIYGDMVFSDCKYEPMATLSTNVP-ILSCGGLAKRWLVPGWRLG 250 Query: 258 WVLGPD-------HIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFP 310 W+L D I L + Q + C T Q A+ + +L R P ++ Sbjct: 251 WILIHDRRDIFGNEIRDGLVKLSQRILGPC-TIVQGAL------KSILQRTPQEFYQDTL 303 Query: 311 QAMQRCRDHMIRSLQSV-GLKPIIPQGSYFLITDISDFKRKMPDLPGAVDEPYDRRFVKW 369 ++ D +L ++ GL+P+ P G+ +L+ I +M P + D F + Sbjct: 304 SFLKSNADLCYGALSAIPGLQPVRPSGAMYLMVGI-----EMEHFPEFEN---DVEFTER 355 Query: 370 MIKNKGLVAIPVSIFYSVPHQKHFDHYIRFCFVKDEATLQAMDEKLRKW 418 +I + + +P + F + ++ R E + +++++ Sbjct: 356 LIAEQSVHCLPATCF-------EYPNFFRVVITVPEVMMLEACSRIQEF 397 >3H14-A nrPDB Length = 391 Score = 277 bits (707), Expect = 8e-75, Method: Composition-based stats. Identities = 91/394 (23%), Positives = 157/394 (39%), Gaps = 45/394 (11%) Query: 26 SEHDVVNLGQGFPDFPPPDFAVEAFQHAVSGDFMLNQYTKTFGYPPLTKILASFFGELLG 85 + ++++ G P P AVEA ++ D + YT G P L + +A +GE G Sbjct: 29 AGRRIIHMEVGQPGTGAPRGAVEALAKSLETDAL--GYTVALGLPALRQRIARLYGEWYG 86 Query: 86 QEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVSLK 145 ++DP R V++T G G AF AL D GD V I P + Y + G PV + Sbjct: 87 VDLDPGR-VVITPGSSGGFLLAFTALFDSGDRVGIGAPGYPSYRQILRALGLVPVDLPTA 145 Query: 146 PGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQQ 205 P + Q P + AG L++ +P NP G + + + Q Sbjct: 146 P----------ENRLQPVPADFAGL---DLAGLMVASPANPTGTMLDHAAMGALIEAAQA 192 Query: 206 HDVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTIGSAGKTFSATGWKVGWVLGPDHI 265 I+DE+Y + Y+ ++ + + I S K FS TGW+VGW++ P+ Sbjct: 193 QGASFISDEIYHGIEYEAKAVTAL----ELTDECYVINSFSKYFSMTGWRVGWMVVPEDQ 248 Query: 266 MKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFPQAMQRCRDHMIRSLQ 325 ++ + + QN P SQ A + + + L + R M+ L Sbjct: 249 VRVVERIAQNMFICAPHASQVAALAALDCDAELQANLD--------VYKANRKLMLERLP 300 Query: 326 SVGL-KPIIPQGSYFLITDISDFKRKMPDLPGAVDEPYDRRFVKWMIKNKGLVAIPVSIF 384 G + P G++++ D+SD R F +++ G+ P F Sbjct: 301 KAGFTRIAPPDGAFYVYADVSDLTDD------------SRAFAAEILEKAGVAVTPGLDF 348 Query: 385 YSVPHQKHFDHYIRFCFVKDEATLQAMDEKLRKW 418 + +RF + + A ++ ++L + Sbjct: 349 ----DPERGAGTLRFSYARATADIEEGLDRLEAF 378 >3DYD-A nrPDB Length = 427 Score = 276 bits (705), Expect = 1e-74, Method: Composition-based stats. Identities = 84/409 (20%), Positives = 171/409 (41%), Gaps = 48/409 (11%) Query: 22 VKLASEHDVVNLGQGFP----DFPPPDFAVEAFQHAVSGDFMLNQYTKTFGYPPLTKILA 77 VK +++L G P + P +A + A+ N Y + G+ + +A Sbjct: 48 VKPNPNKTMISLSIGDPTVFGNLPTDPEVTQAMKDALDSGK-YNGYAPSIGFLSSREEIA 106 Query: 78 SFFGELLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGG 137 S++ + ++V++T G A+ L + G +++ P F Y+ + G Sbjct: 107 SYY--HCPEAPLEAKDVILTSGCSQAIDLCLAVLANPGQNILVPRPGFSLYKTLAESMGI 164 Query: 138 RPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELE 197 +L P +W++D +L +T L++N P+NP G VFS+ L+ Sbjct: 165 EVKLYNLLP----------EKSWEIDLKQLEYLIDEKTACLIVNNPSNPCGSVFSKRHLQ 214 Query: 198 LVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTIGSAGKTFSATGWKVG 257 + ++ + V + DE+Y MV+ ++ +A+L L+ G K + GW++G Sbjct: 215 KILAVAARQCVPILADEIYGDMVFSDCKYEPLATLSTDVP-ILSCGGLAKRWLVPGWRLG 273 Query: 258 WVLGPD-------HIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFP 310 W+L D I L + Q + C T Q A+ + +L R P ++ Sbjct: 274 WILIHDRRDIFGNEIRDGLVKLSQRILGPC-TIVQGAL------KSILCRTPGEFYHNTL 326 Query: 311 QAMQRCRDHMIRSLQSV-GLKPIIPQGSYFLITDISDFKRKMPDLPGAVDEPYDRRFVKW 369 ++ D +L ++ GL+P+ P G+ +L+ I +M P + D F + Sbjct: 327 SFLKSNADLCYGALAAIPGLRPVRPSGAMYLMVGI-----EMEHFPEFEN---DVEFTER 378 Query: 370 MIKNKGLVAIPVSIFYSVPHQKHFDHYIRFCFVKDEATLQAMDEKLRKW 418 ++ + + +P + F + ++IR E + +++++ Sbjct: 379 LVAEQSVHCLPATCF-------EYPNFIRVVITVPEVMMLEACSRIQEF 420 >3AV7-A nrPDB Length = 448 Score = 274 bits (701), Expect = 4e-74, Method: Composition-based stats. Identities = 82/412 (19%), Positives = 162/412 (39%), Gaps = 42/412 (10%) Query: 20 EFVKLASEHDVVNLGQGFPD---FPPP---DFAVEAFQHAVSGDFMLNQYTKTFGYPPLT 73 E +KL D+++L G P+ FP D VE + QY T G+ PL Sbjct: 68 ELLKLVETSDIISLAGGLPNPKTFPKEIIRDILVEIMEKYADKAL---QYGTTKGFTPLR 124 Query: 74 KILASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTM 133 + L + G+ G D ++++T G AL + ++ GD V++ P + Sbjct: 125 ETLMKWLGKRYGISQD--NDIMITSGSQQALDLIGRVFLNPGDIVVVEAPTYLAALQAFN 182 Query: 134 MAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSR 193 + + + L ++ L EL + + T NP G + Sbjct: 183 FYEPQYIQIPLDDEGMKVEILEEK------LKELKSQGKKVKVVYTVPTFQNPAGVTMNE 236 Query: 194 EELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTIGSAGKTFSATG 253 + + + L ++D + + D+ Y + Y G+ I +L R + +G+ K + G Sbjct: 237 DRRKYLLELASEYDFIVVEDDPYGELRYSGNPEKKIKALDNEG-RVIYLGTFSKILA-PG 294 Query: 254 WKVGWVLGPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFPQAM 313 +++GW++G I++ + Q++ Q VA + L + + + Sbjct: 295 FRIGWMVGDPGIIRKMEIAKQSTDLCTNVFGQ-VVAWRYVDGGYL----EKHIPEIRKFY 349 Query: 314 QRCRDHMIRSLQSV---GLKPIIPQGSYFLITDISDFKRKMPDLPGAVDEPYDRRFVKWM 370 + RD M+ +L+ G+K P+G F+ + D ++ ++ Sbjct: 350 KPRRDAMLEALEEFMPEGVKWTKPEGGMFIWVTLPDGI-------------DSKKMLERA 396 Query: 371 IKNKGLVAIPVSIFYSVPHQKHFDHYIRFCFVKDEATLQAMDEKLRKWKVEL 422 IK KG+ +P FY+ K+ + F +V ++ ++ + K EL Sbjct: 397 IK-KGVAYVPGEAFYAHRDVKN-TMRLNFTYVDEDKIMEGIKRLAETIKEEL 446 >1X0M-A nrPDB Length = 403 Score = 272 bits (695), Expect = 2e-73, Method: Composition-based stats. Identities = 82/412 (19%), Positives = 162/412 (39%), Gaps = 42/412 (10%) Query: 20 EFVKLASEHDVVNLGQGFPD---FPPP---DFAVEAFQHAVSGDFMLNQYTKTFGYPPLT 73 E +KL D+++L G P+ FP D VE + QY T G+ PL Sbjct: 23 ELLKLVETSDIISLAGGLPNPKTFPKEIIRDILVEIMEKYADKAL---QYGTTKGFTPLR 79 Query: 74 KILASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTM 133 + L + G+ G D ++++T G AL + ++ GD V++ P + Sbjct: 80 ETLMKWLGKRYGISQD--NDIMITSGSQQALDLIGRVFLNPGDIVVVEAPTYLAALQAFN 137 Query: 134 MAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSR 193 + + + L ++ L EL + + T NP G + Sbjct: 138 FYEPQYIQIPLDDEGMKVEILEEK------LKELKSQGKKVKVVYTVPTFQNPAGVTMNE 191 Query: 194 EELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTIGSAGKTFSATG 253 + + + L ++D + + D+ Y + Y G+ I +L R + +G+ K + G Sbjct: 192 DRRKYLLELASEYDFIVVEDDPYGELRYSGNPEKKIKALDNEG-RVIYLGTFSKILA-PG 249 Query: 254 WKVGWVLGPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFPQAM 313 +++GW++G I++ + Q++ Q VA + L + + + Sbjct: 250 FRIGWMVGDPGIIRKMEIAKQSTDLCTNVFGQ-VVAWRYVDGGYL----EKHIPEIRKFY 304 Query: 314 QRCRDHMIRSLQSV---GLKPIIPQGSYFLITDISDFKRKMPDLPGAVDEPYDRRFVKWM 370 + RD M+ +L+ G+K P+G F+ + D ++ ++ Sbjct: 305 KPRRDAMLEALEEFMPEGVKWTKPEGGMFIWVTLPDGI-------------DSKKMLERA 351 Query: 371 IKNKGLVAIPVSIFYSVPHQKHFDHYIRFCFVKDEATLQAMDEKLRKWKVEL 422 IK KG+ +P FY+ K+ + F +V ++ ++ + K EL Sbjct: 352 IK-KGVAYVPGEAFYAHRDVKN-TMRLNFTYVDEDKIMEGIKRLAETIKEEL 401 >3JTX-A nrPDB Length = 396 Score = 266 bits (679), Expect = 2e-71, Method: Composition-based stats. Identities = 80/401 (19%), Positives = 152/401 (37%), Gaps = 48/401 (11%) Query: 26 SEHDVVNLGQGFPDFPPPDFAVEAFQHAVSGDFMLNQYTKTFGYPPLTKILASFFGELL- 84 + V L G P P P +A ++ L +Y T G P L + A++ Sbjct: 28 EGMEAVPLHIGEPKHPTPKVITDALTASLH---ELEKYPLTAGLPELRQACANWLKRRYD 84 Query: 85 GQEIDPLRNVLVTVGGYGALFTAFQALVDE-----GDEVIIIEPFFDCYEPMTMMAGGRP 139 G +D +L +G ALF+ Q +++ ++ PF+ YE T++ GG Sbjct: 85 GLTVDADNEILPVLGSREALFSFVQTVLNPVSDGIKPAIVSPNPFYQIYEGATLLGGGEI 144 Query: 140 VFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELV 199 F + + ++ D ++ + RTK + + +PNNP G V + + V Sbjct: 145 HFANC-----------PAPSFNPDWRSISEEVWKRTKLVFVCSPNNPSGSVLDLDGWKEV 193 Query: 200 ASLCQQHDVVCITDEVYQWMVYDGHQHI----SIASLPGMWERTLTIGSAGKTFSATGWK 255 L ++ + +DE Y + +DG++ + + A L ++ L S K + G + Sbjct: 194 FDLQDKYGFIIASDECYSEIYFDGNKPLGCLQAAAQLGRSRQKLLMFTSLSKRSNVPGLR 253 Query: 256 VGWVLGPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFPQAMQR 315 G+V G ++K+ Q A +++ EQ + + + Q Sbjct: 254 SGFVAGDAELLKNFLLYRTYHGSAMSIPVQRASIAAWDDEQ--------HVIDNRRLYQE 305 Query: 316 CRDHMIRSLQSVGLKPIIPQGSYFLITDISDFKRKMPDLPGAVDEPYDRRFVKWMIKNKG 375 + +I LQ V +P S+++ + D D F + + + Sbjct: 306 KFERVIPILQQV-FDVKLPDASFYIWLKVPDG--------------DDLAFARNLWQKAA 350 Query: 376 LVAIPVSIFYSVPHQKH-FDHYIRFCFVKDEATLQAMDEKL 415 + +P Q + + Y+R V D AT E + Sbjct: 351 IQVLPGRFLARDTEQGNPGEGYVRIALVADVATCVKAAEDI 391 >1WST-A nrPDB Length = 417 Score = 256 bits (653), Expect = 1e-68, Method: Composition-based stats. Identities = 77/410 (18%), Positives = 152/410 (37%), Gaps = 37/410 (9%) Query: 20 EFVKLASEHDVVNLGQGFP---DFPPPDFAVEAFQHAVSGDFMLNQYTKTFGYPPLTKIL 76 E +KL DV++L G P FP A + QY T G+ PL L Sbjct: 33 ELLKLVETSDVISLAGGLPAPETFPVETIKKIAVEVLEEHADKALQYGTTKGFTPLRLAL 92 Query: 77 ASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAG 136 A + + + + ++ G AL + ++ GD +++ P + Sbjct: 93 ARWMEKRYDIPMSKV-EIMTVAGSQQALDLIGRVFLNPGDPIVVEAPTYLAAIQAFKYYD 151 Query: 137 GRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALV-LNTPNNPLGKVFSREE 195 + + L + G + + +E K R K + ++T NP G S + Sbjct: 152 PEFISIPLD-------DKGMRVDLLEEKLEELRKQGKRVKIVYTVSTFQNPAGVTMSVDR 204 Query: 196 LELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTIGSAGKTFSATGWK 255 + + L ++D + + D Y + Y G I + R + +G+ K + G++ Sbjct: 205 RKKLLELANEYDFLIVEDGPYSELRYSGEPTPPIKHFDD-YGRVIYLGTFSKILA-PGFR 262 Query: 256 VGWVLGPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFPQAMQR 315 +GWV H+++ + Q+ T Q A+A + L + + + + Sbjct: 263 IGWVAAHPHLIRKMEIAKQSIDLCTNTFGQ-AIAWKYVENGYL----DEHIPKIIEFYKP 317 Query: 316 CRDHMIRSLQSV---GLKPIIPQGSYFLITDISDFKRKMPDLPGAVDEPYDRRFVKWMIK 372 RD M+ +L+ G++ P+G F+ + E D + + Sbjct: 318 RRDAMLEALEEYMPEGVEWTKPEGGMFVRVTLP--------------EGIDTKLMMERAV 363 Query: 373 NKGLVAIPVSIFYSVPHQKHFDHYIRFCFVKDEATLQAMDEKLRKWKVEL 422 KG+ +P F+ +K+ + F +V +E + + K E+ Sbjct: 364 AKGVAYVPGEAFFVHRDKKN-TMRLNFTYVPEETIREGVRRLAETIKEEM 412 >2O1B-A nrPDB Length = 404 Score = 253 bits (646), Expect = 9e-68, Method: Composition-based stats. Identities = 68/386 (17%), Positives = 147/386 (38%), Gaps = 38/386 (9%) Query: 30 VVNLGQGFPDFPPPDFAVEAFQHAVSGDFMLNQYTKTFGYPPLTKILASFFGELLGQEID 89 ++N+ G PD P P ++ FQ A++ +Y G + + F+ +D Sbjct: 49 LINMAVGIPDGPTPQGIIDHFQKALTIPEN-QKYGAFHGKEAFKQAIVDFYQRQYNVTLD 107 Query: 90 PLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPI 149 V + G L +++ GD V++ +P + Y ++A G+PV ++L+P Sbjct: 108 KEDEVCILYGTKNGLVAVPTCVINPGDYVLLPDPGYTDYLAGVLLADGKPVPLNLEP--- 164 Query: 150 QNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQQHDVV 209 ++ D ++ + +TK + L PNNP G ++E + + + D Sbjct: 165 --------PHYLPDWSKVDSQIIDKTKLIYLTYPNNPTGSTATKEVFDEAIAKFKGTDTK 216 Query: 210 CITDEVYQWMVYDGHQHISIASLPGMWERTLTIGSAGKTFSATGWKVGWVLGPDHIMKHL 269 + D Y +D +AS G + + I S K ++ +G++VG+ +G +++ L Sbjct: 217 IVHDFAYGAFGFDAKNPSILASENG-KDVAIEIYSLSKGYNMSGFRVGFAVGNKDMIQAL 275 Query: 270 RTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFPQAMQRCRDHMIRSLQSVGL 329 + ++ Q A + + + + RD L L Sbjct: 276 KKYQTHTNAGMFGALQDAAIYALNHY-------DDFLEEQSNVFKTRRDRFEAMLAKADL 328 Query: 330 KPIIPQGSYFLITDISDFKRKMPDLPGAVDEPYDRRFVKWMIKNKGLVAIPVSIFYSVPH 389 + +G ++ + +F +++++ K ++ P F Sbjct: 329 PFVHAKGGIYVWLETPPGY-------------DSEQFEQFLVQEKSILVAPGKPFG---- 371 Query: 390 QKHFDHYIRFCFVKDEATLQAMDEKL 415 ++ + Y+R D+ L +L Sbjct: 372 -ENGNRYVRISLALDDQKLDEAAIRL 396 >2ZC0-A nrPDB Length = 407 Score = 249 bits (636), Expect = 1e-66, Method: Composition-based stats. Identities = 93/428 (21%), Positives = 168/428 (39%), Gaps = 45/428 (10%) Query: 7 ARRLDGIDYNPWVEFVKLASEH-----DVVNLGQGFPDFPPPDFAV-----EAFQHAVSG 56 A R + I + + +K ASE +++L G PD P+ E + + Sbjct: 8 AGRANWIKGSALADVMKKASELQKKGVKLISLAAGDPD---PELIPRAVLGEIAKEVLEK 64 Query: 57 DFMLNQYTKTFGYPPLTKILASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGD 116 + YT G P L + LA+F + E+ P N+++T+GG GAL + L+D GD Sbjct: 65 EPKSVMYTPANGIPELREELAAFLKKYDHLEVSP-ENIVITIGGTGALDLLGRVLIDPGD 123 Query: 117 EVIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTK 176 VI P + G + V + ++ L EL K Sbjct: 124 VVITENPSYINTLLAFEQLGAKIEGVPVDNDGMRVDLLEEKI------KELKAKGQKVKL 177 Query: 177 ALVLNTPNNPLGKVFSREELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMW 236 + T NP+G S E + + + ++D++ I D Y +M Y+G + + +L Sbjct: 178 IYTIPTGQNPMGVTMSMERRKALLEIASKYDLLIIEDTAYNFMRYEGGDIVPLKALDNEG 237 Query: 237 ERTLTIGSAGKTFSATGWKVGWVLGPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQ 296 R + G+ K TG+++GW++ I+K + Q F P SQ E +R Sbjct: 238 -RVIVAGTLSKVLG-TGFRIGWIIAEGEILKKVLMQKQPIDFCAPAISQYIALEYLKRGY 295 Query: 297 LLFRQPSSYFVQFPQAMQRCRDHMIRSLQS--VGLKPIIPQGSYFLITDISDFKRKMPDL 354 + + RD M+++L++ + P F++ + + + Sbjct: 296 F----EKYHLEGALLGYKEKRDIMLKALENHLPNAEFTKPIAGMFVMFFLPEGADGIS-- 349 Query: 355 PGAVDEPYDRRFVKWMIKNKGLVAIPVSIFYSVPHQKHFDHYIRFCFVK-DEATLQAMDE 413 F +++ +G+V +P FY+ K+ IR F + + + + Sbjct: 350 -----------FANELMEREGVVVVPGKPFYTDESGKNA---IRLNFSRPSKEEIPIGIK 395 Query: 414 KLRKWKVE 421 KL K E Sbjct: 396 KLAKLYKE 403 >3ELE-A nrPDB Length = 398 Score = 248 bits (634), Expect = 3e-66, Method: Composition-based stats. Identities = 85/406 (20%), Positives = 155/406 (38%), Gaps = 51/406 (12%) Query: 22 VKLASEHDVVNLGQGFPDFPPPDFAVEAFQHAVSG--DFMLNQYTKTFGYPPLTKILASF 79 + + +V + G P P P + + V+ L+ YT G +A F Sbjct: 29 AAIVGKENVYDFSIGNPSIPAPQIVNDTIKELVTDYDSVALHGYTSAQGDVETRAAIAEF 88 Query: 80 FGELLGQEIDPLRNVLVTVGGYGALFTAFQALV-DEGDEVIIIEPFFDCYEPMTMMAGGR 138 G + N+ +T+G +L F+AL D DE I I P+F Y+ AG R Sbjct: 89 LNNTHGTHFNA-DNLYMTMGAAASLSICFRALTSDAYDEFITIAPYFPEYKVFVNAAGAR 147 Query: 139 PVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELEL 198 V V ++Q+D L + + T+ +++N+PNNP G V+S E ++ Sbjct: 148 LVEVPADT-----------EHFQIDFDALEERINAHTRGVIINSPNNPSGTVYSEETIKK 196 Query: 199 VASLCQQHD------VVCITDEVYQWMVYDGHQHISIASLPGMWERTLTIGSAGKTFSAT 252 ++ L ++ + I DE Y+ +VYDG I + + ++ TL S K+ S Sbjct: 197 LSDLLEKKSKEIGRPIFIIADEPYREIVYDG---IKVPFVTKYYDNTLVCYSYSKSLSLP 253 Query: 253 GWKVGWVLGPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFPQA 312 G ++G+VL PD + +V A S ++ ++ Q ++ A Sbjct: 254 GERIGYVLVPDEVYDKAELYA--AVCGAGRALGYVCAPSLFQKMIVKCQGATGD---INA 308 Query: 313 MQRCRDHMIRSLQSVGLKPIIPQGSYFLITDISDFKRKMPDLPGAVDEPYDRRFVKWMIK 372 + RD + L +G P G++++ E F + K Sbjct: 309 YKENRDLLYEGLTRIGYHCFKPDGAFYMFVK--------------ALEDDSNAFCEK-AK 353 Query: 373 NKGLVAIPVSIFYSVPHQKHFDHYIRFCFVKDEATLQAMDEKLRKW 418 + ++ + F ++R + D ++ K Sbjct: 354 EEDVLIVAADGFGC-------PGWVRISYCVDREMIKHSMPAFEKI 392 >2GB3-A nrPDB Length = 409 Score = 244 bits (622), Expect = 6e-65, Method: Composition-based stats. Identities = 93/422 (22%), Positives = 174/422 (41%), Gaps = 55/422 (13%) Query: 1 MAKQLQARRLDGIDYNPWVEFVKLASEHDVVNLGQGFPDFPPPDFAVEAFQHAVSGDFML 60 + ++ R+L P+ E K + +L G PD P+ F+ + Sbjct: 22 LTEESPIRKL-----VPFAEMAKKRGVR-IHHLNIGQPDLKTPEVF---FERIYENKPEV 72 Query: 61 NQYTKTFGYPPLTKILASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVII 120 Y+ + G L + AS++ ++ P NVLVT GG A+ +F + + GDE+++ Sbjct: 73 VYYSHSAGIWELREAFASYYKRRQRVDVKP-ENVLVTNGGSEAILFSFAVIANPGDEILV 131 Query: 121 IEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVL 180 +EPF+ Y +AG + + V+ + + + P L RTK +VL Sbjct: 132 LEPFYANYNAFAKIAGVKLIPVTRR----------MEEGFAI-PQNLESFINERTKGIVL 180 Query: 181 NTPNNPLGKVFSREELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTL 240 + P NP G V+ ++E+ + + ++H + I DEVY +V+ G + S S+ ++ + Sbjct: 181 SNPCNPTGVVYGKDEMRYLVEIAERHGLFLIVDEVYSEIVFRG-EFASALSI--ESDKVV 237 Query: 241 TIGSAGKTFSATGWKVGWVLG-PDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLF 299 I S K FSA G +VG ++ + ++ H + Q P Q L Sbjct: 238 VIDSVSKKFSACGARVGCLITRNEELISHAMKLAQGR-LAPPLLEQIGSV-------GLL 289 Query: 300 RQPSSYFVQFPQAMQRCRDHMIRSLQSVGLKP-IIPQGSYFLITDISDFKRKMPDLPGAV 358 S+F + + + +++ L+ GLK P G++++ ++ Sbjct: 290 NLDDSFFDFVRETYRERVETVLKKLEEHGLKRFTKPSGAFYITAELP------------- 336 Query: 359 DEPYDRRFVKWMIKNKG-----LVAIPVSIFYSVPHQKHFDHYIRFCFVKDEATLQAMDE 413 F +WM+ + + P+ FY P + IR V ++ L + Sbjct: 337 -VEDAEEFARWMLTDFNMDGETTMVAPLRGFYLTPGLGKKE--IRIACVLEKDLLSRAID 393 Query: 414 KL 415 L Sbjct: 394 VL 395 >1VP4-A nrPDB Length = 425 Score = 243 bits (619), Expect = 2e-64, Method: Composition-based stats. Identities = 81/413 (19%), Positives = 158/413 (38%), Gaps = 36/413 (8%) Query: 11 DGIDYNPWVEFVKLASEHDVVNLGQGFPD---FPPPDFAVEAFQHAVSGDFMLN-QYTKT 66 + + E +K A++ D ++ G G PD FP + A E + + ++ QY+ T Sbjct: 26 QNMKSSIIREILKFAADKDAISFGGGVPDPETFPRKELA-EIAKEIIEKEYHYTLQYSTT 84 Query: 67 FGYPPLTKILASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFD 126 G P L + + + G N++ TVG AL + +D+ ++ +P + Sbjct: 85 EGDPVLKQQILKLLERMYGITGLDEDNLIFTVGSQQALDLIGKLFLDDESYCVLDDPAYL 144 Query: 127 CYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNP 186 V V L+ +G + +L + GK V++ +NP Sbjct: 145 GAINAFRQYLANFVVVPLE----DDGMDLNVLERKLSEFDKNGKIKQVKFIYVVSNFHNP 200 Query: 187 LGKVFSREELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTIGSAG 246 G S E+ + + + +++D+ + D+ Y + Y+G I + G ER + + + Sbjct: 201 AGVTTSLEKRKALVEIAEKYDLFIVEDDPYGALRYEGETVDPIFKIGGP-ERVVLLNTFS 259 Query: 247 KTFSATGWKVGWVLGPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYF 306 K + G ++G V G ++ + Q++ P + A ER LL + Sbjct: 260 KVLA-PGLRIGMVAGSKEFIRKIVQAKQSADLCSPAITHRLAARYLERYDLLEQ-----L 313 Query: 307 VQFPQAMQRCRDHMIRSLQSV-----GLKPIIPQGSYFLITDISDFKRKMPDLPGAVDEP 361 + +R R M+ +L+ G+K + +G F+ LP D Sbjct: 314 KPTIELYRRKRTVMLNALEEYFSDIPGVKWVKSEGGLFIWL----------TLPEGFDTW 363 Query: 362 YDRRFVKWMIKNKGLVAIPVSIFYSVPHQKHFDHYIRFCFVKDEATLQAMDEK 414 + K K + +P +F V + + FC DE ++ + Sbjct: 364 EMFEYAKR----KKVFYVPGRVF-KVYDEPSPSMRLSFCLPPDEKIVEGIKRL 411 >1BW0-A nrPDB Length = 416 Score = 238 bits (607), Expect = 4e-63, Method: Composition-based stats. Identities = 86/409 (21%), Positives = 168/409 (41%), Gaps = 54/409 (13%) Query: 30 VVNLGQGFPDFP----PPDFAVEAFQHAVSGDFMLNQYTKTFGYPPLTKILASFFGELLG 85 ++ L G P ++ + A+ N Y T G P + +A+++ Sbjct: 35 IIKLSVGDPTLDKNLLTSAAQIKKLKEAIDSQE-CNGYFPTVGSPEAREAVATWWRNSFV 93 Query: 86 QEID-----PLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPV 140 + + NV++ GG + A A+ D GD ++ +P F YE + G Sbjct: 94 HKEELKSTIVKDNVVLCSGGSHGILMAITAICDAGDYALVPQPGFPHYETVCKAYGIGMH 153 Query: 141 FVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVA 200 F + +P ++W+ D E+ +TK L++ P+NP G FSR+ +E + Sbjct: 154 FYNCRP----------ENDWEADLDEIRRLKDDKTKLLIVTNPSNPCGSNFSRKHVEDIV 203 Query: 201 SLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERT---LTIGSAGKTFSATGWKVG 257 L ++ + +DE+Y MV+ G + + +E T + +G K GW++G Sbjct: 204 RLAEELRLPLFSDEIYAGMVFKGKDPNATFTSVADFETTVPRVILGGTAKNLVVPGWRLG 263 Query: 258 WVL-------GPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFP 310 W+L GP ++ L+ V C T QAA+ E+ P + Q Sbjct: 264 WLLYVDPHGNGPS-FLEGLKRVGMLVCGPC-TVVQAALGEAL------LNTPQEHLDQIV 315 Query: 311 QAMQRCRDHMIRSL-QSVGLKPIIPQGSYFLITDISDFKRKMPDLPGAVDEPYDRRFVKW 369 ++ ++ + + +GL P +P+G+ +L++ I DL D D F + Sbjct: 316 AKIEESAMYLYNHIGECIGLAPTMPRGAMYLMSRI--------DLEKYRDIKTDVEFFEK 367 Query: 370 MIKNKGLVAIPVSIFYSVPHQKHFDHYIRFCFVKDEATLQAMDEKLRKW 418 +++ + + +P +IF H + R + + E+++ + Sbjct: 368 LLEEENVQVLPGTIF-------HAPGFTRLTTTRPVEVYREAVERIKAF 409 >1IAY-A nrPDB Length = 428 Score = 236 bits (602), Expect = 1e-62, Method: Composition-based stats. Identities = 87/370 (23%), Positives = 148/370 (40%), Gaps = 49/370 (13%) Query: 68 GYPPLTKILASFFGELLG--QEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFF 125 G P K +A F + G DP R V++ G GA T L D GD ++ P++ Sbjct: 84 GLPEFRKAIAKFMEKTRGGRVRFDPER-VVMAGGATGANETIIFCLADPGDAFLVPSPYY 142 Query: 126 DCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQL------DPMELAGKFTSRTKALV 179 + G V L P + SS+N+++ + E A K + K L+ Sbjct: 143 PAFNRDLRWRTG----VQLIPIHCE-----SSNNFKITSKAVKEAYENAQKSNIKVKGLI 193 Query: 180 LNTPNNPLGKVFSREELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERT 239 L P+NPLG ++ L+ V S QH++ + DE+Y V+D Q +SIA + E T Sbjct: 194 LTNPSNPLGTTLDKDTLKSVLSFTNQHNIHLVCDEIYAATVFDTPQFVSIAEILDEQEMT 253 Query: 240 L-------TIGSAGKTFSATGWKVGWVLG-PDHIMKHLRTVHQNSVFHCPTQSQAAVAES 291 + S K G++VG + D ++ R + +S TQ+Q +A Sbjct: 254 YCNKDLVHIVYSLSKDMGLPGFRVGIIYSFNDDVVNCARKM--SSFGLVSTQTQYFLAAM 311 Query: 292 FEREQLLFRQPSSYFVQFPQAMQRCRDHMIRSLQSVGLKPIIPQGSYFLITDISDFKRKM 351 E+ + ++ + + + H L+ VG+K + F D+ R Sbjct: 312 LSDEKFV----DNFLRESAMRLGKRHKHFTNGLEVVGIKCLKNNAGLFCWMDLRPLLR-- 365 Query: 352 PDLPGAVDEPYDRRFVKW--MIKNKGLVAIPVSIFYSVPHQKHFDHYIRFCFVK-DEATL 408 + +D W +I + L P S F + + R CF D+ T+ Sbjct: 366 -------ESTFDSEMSLWRVIINDVKLNVSPGSSF-----ECQEPGWFRVCFANMDDGTV 413 Query: 409 QAMDEKLRKW 418 ++R++ Sbjct: 414 DIALARIRRF 423 >4FL0-A nrPDB Length = 456 Score = 236 bits (602), Expect = 1e-62, Method: Composition-based stats. Identities = 81/428 (18%), Positives = 146/428 (34%), Gaps = 57/428 (13%) Query: 4 QLQARRLDGIDYNPWVEFVKLASEHDVVNLGQGFPDFPPPDFAVEAFQHAVSGD---FML 60 ++ R L+ I+ +P V+ +++LG G P P+ + G Sbjct: 55 EINRRELEHIEKHPNVQ---------LISLGTGDTTEPIPEQITSHMSNFAHGLSTVEGY 105 Query: 61 NQYTKTFGYPPLTKILASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVII 120 Y G L K +A F L V V+ G + Q L+ + + Sbjct: 106 RGYGLEQGNKTLRKAIAETFYRDLHV---KSNEVFVSDGAQSDIS-RLQLLLGSNVTIAV 161 Query: 121 IEPFFDCYEPMTMMAGGRPVFV--SLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKAL 178 +P F Y +++ G F + K + G ++++ D T RT + Sbjct: 162 QDPTFPAYIDSSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDL-----AMTPRTDVI 216 Query: 179 VLNTPNNPLGKVFSREELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWER 238 +PNNP G V SR++L + + + + I D Y + DG SI +PG E Sbjct: 217 FFCSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDG-SPRSIYEIPGAREV 275 Query: 239 TLTIGSAGKTFSATGWKVGWVLGPDH--------IMKHLRTVHQNSVFHCPTQSQAAVAE 290 + + S K TG ++GW + PD I+ + S +QA Sbjct: 276 AIEVSSFSKFAGFTGVRLGWSIIPDELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGLA 335 Query: 291 SFEREQLLFRQPSSYFVQFPQAMQRCRDHMIRSLQSVGLKPIIPQGSYFLITDISDFKRK 350 L + R ++ +L S+GLK + +L K Sbjct: 336 CLSSGGL------KEIRSVNNYYKENRKILMDTLVSLGLKVYGGVNAPYLWVHFKGSKSW 389 Query: 351 MPDLPGAVDEPYDRRFVKWMIKNKGLVAIPVSIFYSVPHQKHFDHYIRFCFVKDEATLQA 410 +++N ++ +P S F + Y+R + Sbjct: 390 --------------DVFNEILENTHIITVPGSGFGPG-----GEEYLRISGFGRRDHIVE 430 Query: 411 MDEKLRKW 418 ++L+ + Sbjct: 431 ASKRLQNF 438 >4IX8-A nrPDB Length = 444 Score = 235 bits (599), Expect = 3e-62, Method: Composition-based stats. Identities = 94/403 (23%), Positives = 158/403 (39%), Gaps = 49/403 (12%) Query: 31 VNLGQGFP----DFPPPDFAVEAFQHAVSGDFMLNQYTKTFGYPPLTKILASFFGELLG- 85 + L G P + PD EA V N Y T G L +++++++ Sbjct: 70 LRLSIGDPTVDGNLKTPDIVTEAMVDVVRSGK-FNGYPPTVGADNLRQVVSTYWRRFCQT 128 Query: 86 ---QEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPVFV 142 QE NV++T G A+ A AL +EGD +++ P F Y+ + G + Sbjct: 129 KSRQEALKWENVIITSGVSQAIVLALTALCNEGDNILVCAPSFPHYKSVCDSYGIECRYY 188 Query: 143 SLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASL 202 L P S +W+ D AG S TKA V+ P+NP G FSR + + Sbjct: 189 YLDP----------SKSWECDLRAAAGMVDSHTKAFVIINPSNPCGSNFSRAHVSDIIDF 238 Query: 203 CQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTIGSAGKTFSATGWKVGWVLGP 262 CQQH + I+DE+Y MV + S+A R L +G K GW+VGW + Sbjct: 239 CQQHQIPLISDEIYAEMVLNNGIFTSVADFDTNVPR-LILGGTAKYQVCPGWRVGWSILI 297 Query: 263 DHIMKH------LRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFPQAMQRC 316 D + + + Q + Q A+A + L + P+ ++ Sbjct: 298 DPMNVAGDWAVGMERLTQLIAG-VNSICQEAIA------RTLLKCPTECTEHIVTQLEAG 350 Query: 317 RDHMIRSLQ-SVGLKPIIPQGSYFLITDISDFKRKMPDLPGAVDEPYDRRFVKWMIKNKG 375 R L+ +G+ PQ S F++ + +L D D F + ++ + Sbjct: 351 AKVYARLLEHDIGISMEAPQASMFVMLKL--------NLSYFQDLKSDMEFYEKLLDEEN 402 Query: 376 LVAIPVSIFYSVPHQKHFDHYIRFCFVKDEATLQAMDEKLRKW 418 + +P IF ++R + A L +++ ++ Sbjct: 403 VQVLPGEIFG-------MSGFLRATVSRPSAVLNEAVDRIIEF 438 >4CVQ-A nrPDB Length = 431 Score = 234 bits (596), Expect = 6e-62, Method: Composition-based stats. Identities = 75/403 (18%), Positives = 159/403 (39%), Gaps = 45/403 (11%) Query: 26 SEHDVVNLGQGFP---DFPPPDFAVEAFQHAVSGDFMLNQYTKTFGYPPLTKILASFFGE 82 + V+ L G P F PD E + Y + G K + + Sbjct: 57 EGNKVLKLNIGNPAPFGFDAPD---EILVDVIRNLPTAQGYCDSKGLYSARKAIMQHYQA 113 Query: 83 LLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPVFV 142 G + ++ + G + A QAL++ GDE+++ P + + ++ G+ V Sbjct: 114 R-GMRDVTVEDIYIGNGVSELIVQAMQALLNSGDEMLVPAPDYPLWTAAVSLSSGKAVHY 172 Query: 143 SLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASL 202 SS+W D ++ K T RT+ +V+ PNNP G V+S+E L + + Sbjct: 173 LCD----------ESSDWFPDLDDIRAKITPRTRGIVIINPNNPTGAVYSKELLMEIVEI 222 Query: 203 CQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTIGSAGKTFSATGWKVGWVLGP 262 +QH+++ DE+Y ++YD +H SIA L T+T KT+ G++ GW++ Sbjct: 223 ARQHNLIIFADEIYDKILYDDAEHHSIAPLAPDL-LTITFNGLSKTYRVAGFRQGWMVLN 281 Query: 263 DHI------MKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFPQAMQRC 316 ++ L + + +Q A+ + ++ S + + ++ Sbjct: 282 GPKKHAKGYIEGLEML-ASMRLCANVPAQHAIQTALGG----YQSISEFITPGGRLYEQ- 335 Query: 317 RDHMIRSLQSV-GLKPIIPQGSYFLITDISDFKRKMPDLPGAVDEPYDRRFVKWMIKNKG 375 R+ + + G+ + P+G+ ++ I + + D D++ V + + Sbjct: 336 RNRAWELINDIPGVSCVKPRGALYMFPKIDAKRFNIHD---------DQKMVLDFLLQEK 386 Query: 376 LVAIPVSIFYSVPHQKHFDHYIRFCFVKDEATLQAMDEKLRKW 418 ++ + + F + + R + ++ K ++ Sbjct: 387 VLLVQGTAF-----NWPWPDHFRIVTLPRVDDIELSLSKFARF 424 >4DQ6-A nrPDB Length = 391 Score = 234 bits (596), Expect = 7e-62, Method: Composition-based stats. Identities = 70/412 (16%), Positives = 155/412 (37%), Gaps = 53/412 (12%) Query: 15 YNPWVEFVKLASEHDVVNLGQGFPDFPPPDFAVEAFQHAVSGDFMLNQYTKTFGYPPLTK 74 + W E K +D++ + DF +++ ++ + + Y T + Sbjct: 19 SSKWSEMEKKYGTNDLLPMWVADMDFKAAPCIIDSLKNRLEQEI----YGYTTRPDSYNE 74 Query: 75 ILASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTMM 134 + ++ +I ++ + G A+ L D+++I EP + + + Sbjct: 75 SIVNWLYRRHNWKIK-SEWLIYSPGVIPAISLLINELTKANDKIMIQEPVYSPFNSVVKN 133 Query: 135 AGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSRE 194 + L + + N+ +D ++ K K +L P+NP+G+V++++ Sbjct: 134 NNRELIISPL--------QKLENGNYIMDYEDIENKIKD-VKLFILCNPHNPVGRVWTKD 184 Query: 195 ELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWE-RTLTIGSAGKTFSATG 253 EL+ + +C +H+V I+DE++ ++ H+HI +AS+ +E T+T + KTF+ G Sbjct: 185 ELKKLGDICLKHNVKIISDEIHSDIILKKHKHIPMASISKEFEKNTITCMAPTKTFNIAG 244 Query: 254 WKVGWVLGPDHIMKHLR-------TVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYF 306 + +V+ PD L + +N+ F + + S+ Sbjct: 245 LQSSYVVLPDEKDYKLLDDAFTRIDIKRNNCFS------------LVATEASYNNGESWL 292 Query: 307 VQFPQAMQRCRDHMIRSLQS--VGLKPIIPQGSYFLITDISDFKRKMPDLPGAVDEPYDR 364 F + ++ D I+ + LK P+G+Y L D S D Sbjct: 293 ESFLEYLESNIDFAIKYINENMPKLKVRKPEGTYLLWVDFSALG------------LSDE 340 Query: 365 RFVKWMIKNKGLVAIPVSIFYSVPHQKHFDHYIRFCFVKDEATLQAMDEKLR 416 +++ + + F Y R + L+ +++ Sbjct: 341 ELESILVQKGKVALNQGNSFGIG-----GSGYQRINLACPRSMLEEALIRIK 387 >5Z0Q-C nrPDB Length = 389 Score = 224 bits (571), Expect = 5e-59, Method: Composition-based stats. Identities = 82/414 (19%), Positives = 151/414 (36%), Gaps = 59/414 (14%) Query: 12 GIDYNPWVEFVKLASEHDVVNLGQGFPDFPPPDFAVEAFQHAVSGDFMLNQYTKTFGYPP 71 D W K ++ D++ L DF D ++A Q V FGY Sbjct: 21 HSDSLKW----KKYADRDILPLWIADTDFRAADCIIDALQQRVQQGV--------FGYGV 68 Query: 72 LTKILAS----FFGELLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDC 127 ++ LA G +I P ++ G + A +A + + P + Sbjct: 69 TSEALAEVAIERMESRFGWKIQP-EWLVFLPGVVTGINIAVRAFTEAHQSTVSATPIYPP 127 Query: 128 YEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPL 187 + +AG + + +L+ W LD + + K L+L P+NP Sbjct: 128 FFLAPKLAGRQHLSAALRL---------EQQRWVLDLDSHEDRMSGNEKLLLLCNPHNPG 178 Query: 188 GKVFSREELELVASLCQQHDVVCITDEVYQWMVYD-GHQHISIASL-PGMWERTLTIGSA 245 G V+ R+ELE Q+HD++ +DE++ +V + G QHI ASL +R++T+ S Sbjct: 179 GTVYRRKELEAQLRFAQRHDLLVCSDEIHCDLVLEPGVQHIPFASLSDDAAQRSITLMSP 238 Query: 246 GKTFSATGWKVGWVLGP-DHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSS 304 K+F+ G + P + + + V + A + ++ R+ Sbjct: 239 SKSFNIAGLGASLAVIPNPELRARFNRMRKGMVPDVDVLAYVAASAAW-------REGQP 291 Query: 305 YFVQFPQAMQRCRDHMIRSLQSV-GLKPIIPQGSYFLITDISDFKRKMPDLPGAVDEPYD 363 + ++ RD + + + + GL + P+ S+ D S P L Sbjct: 292 WLDAQLDYLRANRDMLAQHVNRLPGLSMVTPEASFLGWIDASGLGVADPAL--------- 342 Query: 364 RRFVKWMIKNKGLVAIPVSIFYSVPHQKHFDHYIRFCFVKDEATLQAMDEKLRK 417 + GL F D ++RF F L+ +++ + Sbjct: 343 ------FFEKHGLGFSSGRDFG-------NDRFVRFNFGCPRQLLEEALQRMTR 383 >2DOU-A nrPDB Length = 376 Score = 223 bits (568), Expect = 1e-58, Method: Composition-based stats. Identities = 87/399 (21%), Positives = 150/399 (37%), Gaps = 43/399 (10%) Query: 20 EFVKLASEHDV--VNLGQGFPDFPPPDFAVEAFQHAVSGDFMLNQYTKTFGYPPLTKILA 77 E + A E V ++L G D PPP+ ++A A+ D Y P + A Sbjct: 15 EAKRKARERGVGLIDLSIGSTDLPPPEAPLKALAEAL-NDPTTYGYCLKSCTLPFLEEAA 73 Query: 78 SFFGELLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGG 137 ++ G +DP R L +G L AL + D +++ E + Y +A Sbjct: 74 RWYEGRYGVGLDPRREALALIGSQEGLAHLLLALTEPEDLLLLPEVAYPSYFGAARVASL 133 Query: 138 RPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELE 197 R + L+ + + + W+ K L+LN PNNP G V E Sbjct: 134 RTFLIPLREDGLADLKAVPEGVWR------------EAKVLLLNYPNNPTGAVADWGYFE 181 Query: 198 LVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTIGSAGKTFSATGWKVG 257 L ++H + I D Y VY+G +A LPG ER + + S K+++ G+++G Sbjct: 182 EALGLARKHGLWLIHDNPYVDQVYEGEAPSPLA-LPGAKERVVELFSLSKSYNLAGFRLG 240 Query: 258 WVLGPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFPQAMQRCR 317 + LG + + L V F+ Q A E + P + + + Sbjct: 241 FALGSEEALARLERVKGVIDFN-----QYAGVLRMGVE--ALKTPKEVVRGYARVYRERA 293 Query: 318 DHMIRSLQSVGLKPIIPQGSYFLITDISDFKRKMPDLPGAVDEPYDRRFVKWMIKNKGLV 377 M +L+ V L + P+ + +L LP VD D F +++ +G+ Sbjct: 294 LGMAEALKGV-LSLLPPRATMYLW----------GRLPEGVD---DLEFGLRLVE-RGVA 338 Query: 378 AIPVSIFYSVPHQKHFDHYIRFCFVKDEATLQAMDEKLR 416 ++R V+ L +++R Sbjct: 339 LA-----PGRGFGPGGKGFVRIALVRPLEELLEAAKRIR 372 >3L8A-A nrPDB Length = 421 Score = 222 bits (566), Expect = 2e-58, Method: Composition-based stats. Identities = 75/394 (19%), Positives = 158/394 (40%), Gaps = 43/394 (10%) Query: 27 EHDVVNLGQGFPDFPPPDFAVEAFQHAVSGDFMLNQYTKTFGYPPLTKILASFFGELLGQ 86 +++ + DF P EA + G + Y + L + + + + Sbjct: 60 NPELLQMWVADMDFLPVPEIKEAIINY--GREHIFGY--NYFNDDLYQAVIDWERKEHDY 115 Query: 87 EIDPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVSLKP 146 + ++L G A+ A QA ++GD V+I P + + + R V SL+ Sbjct: 116 AV-VKEDILFIDGVVPAISIALQAFSEKGDAVLINSPVYYPFARTIRLNDHRLVENSLQI 174 Query: 147 GPIQNGELGSSSNWQLDPMELAGKFTSR-TKALVLNTPNNPLGKVFSREELELVASLCQQ 205 + +++D +L K +L +P+NP G+V+ ++L +A LC++ Sbjct: 175 I---------NGRFEIDFEQLEKDIIDNNVKIYLLCSPHNPGGRVWDNDDLIKIAELCKK 225 Query: 206 HDVVCITDEVYQWMVYDGHQHISIASLPGMW-ERTLTIGSAGKTFSATGWKVGWVLGPDH 264 H V+ ++DE++Q + G+ H S+ +L + + T+ + SA KTF+ G K + + + Sbjct: 226 HGVILVSDEIHQDLALFGNTHHSLNTLDASYKDFTIILSSATKTFNIAGTKNSFAIIQNE 285 Query: 265 IMKHLRTVHQ--NSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFPQAMQRCRDHMIR 322 ++ Q N+ PT A +F + + + ++ +I+ Sbjct: 286 SLRRKFQYRQLANNQHEVPTVGMIATQAAF-------QYGKPWLEELKTVIEGNIKLVIK 338 Query: 323 SLQS-VGLKPIIPQGSYFLITDISDFKRKMPDLPGAVDEPYDRRFVKWMIKNKGLVAIPV 381 L++ +K + P+G+Y + D S + P L + + +V Sbjct: 339 ELEAKTKIKVMEPEGTYLVWLDFSAYAIAQPQL------------SEKLQNEAKVVLNDG 386 Query: 382 SIFYSVPHQKHFDHYIRFCFVKDEATLQAMDEKL 415 + F K ++ R + T+Q ++ Sbjct: 387 AHFG-----KEGKYFARLNVATPKNTVQEALSRI 415 >3ASB-A nrPDB Length = 400 Score = 222 bits (566), Expect = 2e-58, Method: Composition-based stats. Identities = 69/403 (17%), Positives = 134/403 (33%), Gaps = 44/403 (10%) Query: 19 VEFVKLASEHDVVNLGQGFPDFPPPDFAVEAFQHAV---SGDFMLNQYTKTFGYPPLTKI 75 +F +H V+NL G P EAF ++ S Y FG P L + Sbjct: 24 AQFRLENPQHTVINLSIGDTTQPLNASVAEAFASSIARLSSPTTCRGYGPDFGLPALRQK 83 Query: 76 LASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMA 135 L+ F +D + ++ G LF + V I +P + Y + + Sbjct: 84 LSEDFYRGF---VDAKE-IFISDGAKVDLFRLL-SFFGPNQTVAIQDPSYPAYLDIARLT 138 Query: 136 GGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREE 195 G + + + + + E + L L +PNNP G V ++++ Sbjct: 139 GAKEIIA---------LPCLQENAFFPEFPE-----DTHIDILCLCSPNNPTGTVLNKDQ 184 Query: 196 LELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTIGSAGKTFSATGWK 255 L + +H+++ + D Y + D SI +P + I S K G + Sbjct: 185 LRAIVHYAIEHEILILFDAAYSTFISDPSLPKSIFEIPDARFCAIEINSFSKPLGFAGIR 244 Query: 256 VGWVLGPDHIMKH--LRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFPQAM 313 +GW + P + + F T + A++ L P ++ Sbjct: 245 LGWTVIPQELTYADGHFVIQDWERFLSTTFNGASIPAQEAGVAGLSILPQ---LEAIHYY 301 Query: 314 QRCRDHMIRSLQSVGLKPIIPQGSYFLITDISDFKRKMPDLPGAVDEPYDRRFVKWMIKN 373 + D + ++L + G + + + +L DR + ++ Sbjct: 302 RENSDLLRKALLATGFEVFGGEHAPYLWVK------------PTQANISDRDLFDFFLRE 349 Query: 374 KGLVAIPVSIFYSVPHQKHFDHYIRFCFVKDEATLQAMDEKLR 416 + P F ++RF + + A E+L+ Sbjct: 350 YHIAITPGIGFGRS-----GSGFVRFSSLGKREDILAACERLQ 387 >3T32-A nrPDB Length = 383 Score = 221 bits (563), Expect = 5e-58, Method: Composition-based stats. Identities = 69/397 (17%), Positives = 150/397 (37%), Gaps = 43/397 (10%) Query: 25 ASEHDVVNLGQGFPDFPPPDFAVEAFQHAVSGD-FMLNQYTKTFGYPPLTKILASFFGEL 83 ++++ DF P A + + F + G I+ ++ + Sbjct: 21 YKNEELIHAWIADMDFEVPQPIQTALKKRIEHPIFGYTLPPENIG-----DIICNWTKKQ 75 Query: 84 LGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVS 143 +I ++ + G AL T+ QA E + V++ P + + M + Sbjct: 76 YNWDIQK-EWIVFSAGIVPALSTSIQAFTKENESVLVQPPIYPPFFEMVTTNNRQLCVSP 134 Query: 144 LKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASLC 203 L+ + + +D L +F K ++L +P+NP+G+V+ +EEL + SLC Sbjct: 135 LQ---------KQNDTYAIDFEHLEKQFQQGVKLMLLCSPHNPIGRVWKKEELTKLGSLC 185 Query: 204 QQHDVVCITDEVYQWMVYDGHQHISIASLPGM-WERTLTIGSAGKTFSATGWKVGWVLGP 262 +++V+ + DE++ ++Y H H ASL RT+T + KTF+ G + ++ P Sbjct: 186 TKYNVIVVADEIHSDIIYADHTHTPFASLSEELAARTITCMAPSKTFNIAGLQASIIIIP 245 Query: 263 DHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFPQAMQRCRDHMIR 322 + ++ T Q ++ Q + + + + + ++ Sbjct: 246 NEKLRQAFTSIQYRQG-----FHGLNIFAYTAMQSAYTECNDWLNEIRFYIEDNAKFACE 300 Query: 323 SLQS--VGLKPIIPQGSYFLITDISDFKRKMPDLPGAVDEPYDRRFVKWMIKNKGLVAI- 379 ++ L + P+GS+ L D S + +++ KG + + Sbjct: 301 YIKDHIPTLSVMKPEGSFLLWIDCSALNLSQDERT-------------KLLEEKGKIIVE 347 Query: 380 PVSIFYSVPHQKHFDHYIRFCFVKDEATLQAMDEKLR 416 P + + +I + L+ + +LR Sbjct: 348 PGEKYGLG-----GEEHIGINIGCPRSVLEEILNRLR 379 >3B1C-A nrPDB Length = 392 Score = 221 bits (562), Expect = 6e-58, Method: Composition-based stats. Identities = 76/397 (19%), Positives = 150/397 (37%), Gaps = 40/397 (10%) Query: 23 KLASEHDVVNLGQGFPDFPPPDFAVEAFQHAVSGDFMLNQYTKTFGYPPLTKILASFFGE 82 + ++ ++ DF +A Y T+ L + + + Sbjct: 26 ETETDPQLLPAWIADMDFEVMPEVKQAIHDYAEQLV----YGYTYASDELLQAVLDWEKS 81 Query: 83 LLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPVFV 142 D +++ G A+ A QA EG+ V+I P + + + + V Sbjct: 82 EHQYSFDK-EDIVFVEGVVPAISIAIQAFTKEGEAVLINSPVYPPFARSVRLNNRKLVSN 140 Query: 143 SLKPGPIQNGELGSSSNWQLDPMELAGKFTSR-TKALVLNTPNNPLGKVFSREELELVAS 201 SLK + +Q+D +L K +L P+NP G+V+ RE LE + Sbjct: 141 SLK---------EENGLFQIDFEQLENDIVENDVKLYLLCNPHNPGGRVWEREVLEQIGH 191 Query: 202 LCQQHDVVCITDEVYQWMVYDGHQHISIASL-PGMWERTLTIGSAGKTFSATGWKVGWVL 260 LCQ+H V+ ++DE++Q + GH+H+S ++ P + L + SA KTF+ G K + + Sbjct: 192 LCQKHHVILVSDEIHQDLTLFGHEHVSFNTVSPDFKDFALVLSSATKTFNIAGTKNSYAI 251 Query: 261 GPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFPQAMQRCRDHM 320 + + Q H S +A + +R + V ++ Sbjct: 252 IENPTLCAQFKHQQLVNNHHEVSSLGYIA-----TETAYRYGKPWLVALKAVLEENIQFA 306 Query: 321 IRSL--QSVGLKPIIPQGSYFLITDISDFKRKMPDLPGAVDEPYDRRFVKWMIKNKGLVA 378 + ++ LK + PQG+Y + D SD+ D F + ++ Sbjct: 307 VEYFAQEAPRLKVMKPQGTYLIWLDFSDYG-----------LTDDALFTL-LHDQAKVIL 354 Query: 379 IPVSIFYSVPHQKHFDHYIRFCFVKDEATLQAMDEKL 415 S + S + + R ++ ++ + +++ Sbjct: 355 NRGSDYGS-----EGELHARLNIAAPKSLVEEICKRI 386 >3NRA-A nrPDB Length = 407 Score = 220 bits (560), Expect = 1e-57, Method: Composition-based stats. Identities = 90/387 (23%), Positives = 143/387 (36%), Gaps = 32/387 (8%) Query: 31 VNLGQGFPDFPPPDFAVEAFQHAVSGDFMLNQYTKTFGYPPLTKILASFFGELLGQEIDP 90 V+ G D P A + YT+ G + +LA G +D Sbjct: 42 VDFSHGDVDAHEPTPGAFDLFSAGVQSGGVQAYTEYRGDLGIRDLLAPRLAAFTGAPVDA 101 Query: 91 LRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPIQ 150 +++T G GALF A A V GD+V I++P + + G V V L Sbjct: 102 RDGLIITPGTQGALFLAVAATVARGDKVAIVQPDYFANRKLVEFFEGEMVPVQLDYVSAD 161 Query: 151 NGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQQHDVVC 210 G LD L F + + + + PNNP G V+S EE+ +A+L ++ Sbjct: 162 ETRAG------LDLTGLEEAFKAGARVFLFSNPNNPAGVVYSAEEIGQIAALAARYGATV 215 Query: 211 ITDEVYQWMVYDGHQHISI-ASLPGMWERTLTIGSAGKTFSATGWKVGWVLGPDHIMKHL 269 I D++Y + Y G + + A E +TI KT S +G+++G G I+ + Sbjct: 216 IADQLYSRLRYAGASYTHLRAEAAVDAENVVTIMGPSKTESLSGYRLGVAFGSRAIIARM 275 Query: 270 RTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFPQAMQRCRDHMIRSLQSV-G 328 + SQA + + F + + Q RD ++ L+ G Sbjct: 276 EKLQAIVSLRAAGYSQAVL-------RGWFDEAPGWMEDRIARHQAIRDELLHVLRGCEG 328 Query: 329 LKPIIPQGSYFLITDISDFKRKMPDLPGAVDEPYDRRFVKWMIKNKGLVAIPVSIFYSVP 388 + PQ +L P LP P FVK + G+V P + F Sbjct: 329 VFARTPQAGSYLF----------PRLPKLAVAP--AEFVKILRLQAGVVVTPGTEF---- 372 Query: 389 HQKHFDHYIRFCFVKDEATLQAMDEKL 415 H +R F +D A ++ Sbjct: 373 -SPHTADSVRLNFSQDHEAAVAAARRI 398 >3G7Q-A nrPDB Length = 417 Score = 214 bits (545), Expect = 5e-56, Method: Composition-based stats. Identities = 81/414 (19%), Positives = 141/414 (34%), Gaps = 45/414 (10%) Query: 26 SEHDVVNLGQGFPDFPPP--DFAVEAFQHAVSGDFMLNQ---YTKTFGYPPLTKILASFF 80 + LG G P P D+ V + Y G L LA Sbjct: 29 RTPGAIMLGGGNPAHIPAMQDYFQTLLTDMVESGKAADALCNYDGPQGKTALLNALAVLL 88 Query: 81 GELLGQEIDPLRNVLVTVGGYGALFTAFQALVD---EGDEVIIIEPFFDCYEPMTMMAGG 137 E LG +I+P +N+ +T G A F F +G ++ P Y Sbjct: 89 RETLGWDIEP-QNIALTNGSQSAFFYLFNLFAGRRADGSTKKVLFPLAPEYIGYADSGLE 147 Query: 138 RPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELE 197 +FVS +P N EL ++ T + ++ P NP G V + EEL Sbjct: 148 DDLFVSARP----NIELLPEGQFKYHVDFEHLHIGEETGMICVSRPTNPTGNVITDEELM 203 Query: 198 LVASLCQQHDVVCITDEVYQ----WMVYDGHQHISIASLPGMWERTLTIGSAGKTFSATG 253 + L QH++ + D Y +++ + + + S K G Sbjct: 204 KLDRLANQHNIPLVIDNAYGVPFPGIIFSEARPL-------WNPNIILCMSLSK-LGLPG 255 Query: 254 WKVGWVLGPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFPQAM 313 + G ++ D + + ++ A + E +R LL + + Q + Sbjct: 256 SRCGIIIANDKTITAIANMNGIISLAPGGMGPAMMCEMIKRNDLLRLSETVIKPFYYQRV 315 Query: 314 QRCRDHMIRSLQSVGLKPIIPQGSYFLITDISDFKRKMPDLPGAVDEPYDRRFVKWMIKN 373 Q+ + R L P+G+ FL DLP + Y R +K Sbjct: 316 QQTIAIIRRYLSEERCLIHKPEGAIFLWL-------WFKDLPITTELLYQR------LKA 362 Query: 374 KGLVAIPVSIFYSVPHQ--KHFDHYIRFCFVKDEATLQA-----MDEKLRKWKV 420 +G++ +P F+ + H +R +V + ++A +E R W+ Sbjct: 363 RGVLMVPGHYFFPGLDKPWPHTHQCMRMNYVPEPDKIEAGVKILAEEIERAWRE 416 >3OP7-A nrPDB Length = 375 Score = 214 bits (545), Expect = 6e-56, Method: Composition-based stats. Identities = 69/356 (19%), Positives = 135/356 (37%), Gaps = 47/356 (13%) Query: 63 YTKTFGYPPLTKILASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIE 122 Y G P K ++ + + P +L T G GA +L++ GD VI + Sbjct: 59 YGWIEGSPAFKKSVSQLY-----TGVKP-EQILQTNGATGANLLVLYSLIEPGDHVISLY 112 Query: 123 PFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNT 182 P + + G + ++ + W D +L TK + +N Sbjct: 113 PTYQQLYDIPKSLGAE----------VDLWQIEEENGWLPDLEKLRQLIRPTTKMICINN 162 Query: 183 PNNPLGKVFSREELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTI 242 NNP G V R LE + + + ++DEVY+ + + S+ ++++ + + Sbjct: 163 ANNPTGAVMDRTYLEELVEIASEVGAYILSDEVYRSF-----SELDVPSIIEVYDKGIAV 217 Query: 243 GSAGKTFSATGWKVGWVLGPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQP 302 S KT+S G ++GWV + LR ++ + Sbjct: 218 NSLSKTYSLPGIRIGWVAANHQVTDILRDYRDYTMICAGVFDDLVAQLAL---------- 267 Query: 303 SSYFVQFPQAMQRCRDHMIRSLQSVGLKPIIPQGSYFLITDISDFKRKMPDLPGAVDEPY 362 + + ++R R + +L ++ + I + L++ I + AVD P Sbjct: 268 ----AHYQEILERNRHILEENL-AILDQWIEEEP---LVSYIRPAVVSTSFVKIAVDMPM 319 Query: 363 DRRFVKWMIKNKGLVAIPVSIFYSVPHQKHFDHYIRFCFVKDEATLQAMDEKLRKW 418 + F +++ G++ +P + F D Y+R F ++ TL EKL ++ Sbjct: 320 E-DFCLQLLQEHGVLLVPGNRF-------ERDGYVRLGFACEQETLIKGLEKLSQF 367 >1M4N-A nrPDB Length = 435 Score = 213 bits (541), Expect = 1e-55, Method: Composition-based stats. Identities = 71/363 (19%), Positives = 139/363 (38%), Gaps = 33/363 (9%) Query: 68 GYPPLTKILASFFGELLG--QEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFF 125 G P K + F E+ G DP ++++T G A T L D G+ V+I P++ Sbjct: 87 GLPAFKKAMVDFMAEIRGNKVTFDP-NHLVLTAGATSANETFIFCLADPGEAVLIPTPYY 145 Query: 126 DCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNN 185 ++ G + V + ++ ++ + + A K R K +++ P+N Sbjct: 146 PGFDRDLKWRTGVEI-VPIHCTSSNGFQITETA--LEEAYQEAEKRNLRVKGVLVTNPSN 202 Query: 186 PLGKVFSREELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASL---------PGMW 236 PLG +R EL L+ S + + I+DE+Y + IS+ + +W Sbjct: 203 PLGTTMTRNELYLLLSFVEDKGIHLISDEIYSGTAFSSPSFISVMEVLKDRNCDENSEVW 262 Query: 237 ERTLTIGSAGKTFSATGWKVGWVLGPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQ 296 +R + S K G++VG + D ++ T +S +Q+Q ++ ++ Sbjct: 263 QRVHVVYSLSKDLGLPGFRVGAIYSNDDMVVAAAT-KMSSFGLVSSQTQHLLSAMLSDKK 321 Query: 297 LLFRQPSSYFVQFPQAMQRCRDHMIRSLQSVGLKPIIPQGSYFLITDISDFKRKMPDLPG 356 L +Y + + +++ + ++ LQ G+ + F D+ R Sbjct: 322 LT----KNYIAENHKRLKQRQKKLVSGLQKSGISCLNGNAGLFCWVDMRHLLRSNT---- 373 Query: 357 AVDEPYDRRFVKWMIKNKGLVAIPVSIFYSVPHQKHFDHYIRFCFVK-DEATLQAMDEKL 415 + K ++ L P S + R CF E TL ++L Sbjct: 374 ---FEAEMELWKKIVYEVHLNISPGS-----SCHCTEPGWFRVCFANLPERTLDLAMQRL 425 Query: 416 RKW 418 + + Sbjct: 426 KAF 428 >3EI8-A nrPDB Length = 432 Score = 211 bits (537), Expect = 4e-55, Method: Composition-based stats. Identities = 67/428 (15%), Positives = 135/428 (31%), Gaps = 57/428 (13%) Query: 4 QLQARRLDGIDYNPWVEFVKLASEHDVVNLGQGFPDFPPPDFAVEAFQH---AVSGDFML 60 ++ RR + P + V++LG G P P+ A +S Sbjct: 41 EIARRRSAHLLKYPDAQ---------VISLGIGDTTEPIPEVITSAMAKKAHELSTIEGY 91 Query: 61 NQYTKTFGYPPLTKILASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVII 120 + Y G PL +A F LG D +V V+ G + Q + + + Sbjct: 92 SGYGAEQGAKPLRAAIAKTFYGGLGIGDD---DVFVSDGAKCDIS-RLQVMFGSNVTIAV 147 Query: 121 IEPFFDCYEPMTMMAGGRPVFVSL--KPGPIQNGELGSSSNWQLDPMELAGKFTSRTKAL 178 +P + Y +++ G F + K G I+ + + D + RT + Sbjct: 148 QDPSYPAYVDSSVIMGQTGQFNTDVQKYGNIEYMRCTPENGFFPDLSTV-----GRTDII 202 Query: 179 VLNTPNNPLGKVFSREELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWER 238 +PNNP G +RE+L + +++ + + D Y + D + SI +PG E Sbjct: 203 FFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPR-SIFEIPGAEEV 261 Query: 239 TLTIGSAGKTFSATGWKVGWVLGPDHIM--------KHLRTVHQNSVFHCPTQSQAAVAE 290 + S TG ++GW + P ++ K + SQA Sbjct: 262 AMETASFSNYAGFTGVRLGWTVIPKKLLYSDGFPVAKDFNRIICTCFNGASNISQAGALA 321 Query: 291 SFEREQLLFRQPSSYFVQFPQAMQRCRDHMIRSLQSVGLKPIIPQGSYFLITDISDFKRK 350 E L + + + +I + S+G + + ++ + Sbjct: 322 CLTPEGL------EAMHKVIGFYKENTNIIIDTFTSLGYDVYGGKNAPYVWVHFPNQSSW 375 Query: 351 MPDLPGAVDEPYDRRFVKWMIKNKGLVAIPVSIFYSVPHQKHFDHYIRFCFVKDEATLQA 410 +++ +V + ++R + Sbjct: 376 --------------DVFAEILEKTHVVTT-----PGSGFGPGGEGFVRVSAFGHRENILE 416 Query: 411 MDEKLRKW 418 + ++ Sbjct: 417 ACRRFKQL 424 >3QGU-A nrPDB Length = 449 Score = 210 bits (535), Expect = 7e-55, Method: Composition-based stats. Identities = 62/428 (14%), Positives = 133/428 (31%), Gaps = 57/428 (13%) Query: 4 QLQARRLDGIDYNPWVEFVKLASEHDVVNLGQGFPDFPPPDFAVEAFQHAVS---GDFML 60 ++ RR + NP + +++LG G P P + +A A + Sbjct: 54 EIARRRKAHQEKNP---------DAKIISLGIGDTTEPLPKYIADAMAKAAAGLATREGY 104 Query: 61 NQYTKTFGYPPLTKILASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVII 120 + Y G L + +AS F G + ++ G + Q + V + Sbjct: 105 SGYGAEQGQGALREAVASTF---YGHAGRAADEIFISDGSKCDIA-RIQMMFGSKPTVAV 160 Query: 121 IEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVL 180 +P + Y ++M G I+ +++ D + RT + Sbjct: 161 QDPSYPVYVDTSVMMGMTGDHNGTGFDGIEYMVCNPDNHFFPDLSKA-----KRTDIIFF 215 Query: 181 NTPNNPLGKVFSREELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTL 240 +PNNP G +R +L + + +++ + + D Y + + +I +PG E + Sbjct: 216 CSPNNPTGAAATRAQLTELVNFARKNGSILVYDAAYALYISNPDCPKTIYEIPGADEVAI 275 Query: 241 TIGSAGKTFSATGWKVGWVLGPDHIMKH--------LRTVHQNSVFHCPTQSQAAVAESF 292 S K TG ++GW + P + V QA Sbjct: 276 ETCSFSKYAGFTGVRLGWTVVPKALKYANGEPVHADWNRVMTTCFNGASNIVQAGGLACL 335 Query: 293 EREQLLFRQPSSYFVQFPQAMQRCRDHMIRSLQSVGLKPIIPQGSYFLITDISDFKRKMP 352 + E L + + + + +G + ++ Sbjct: 336 QPEGL------KEMNAMIKFYKENAQILKTTFTEMGFSVYGGDDAPYIWVGFPGKPSW-- 387 Query: 353 DLPGAVDEPYDRRFVKWMIKNKGLVAIPVSIFYSVPHQKHFDHYIRFCFVKDEATLQAMD 412 +++ +V P S + + ++R + + + Sbjct: 388 ------------DVFAEILERCNIVTTPGSGYG-----PAGEGFVR---ASAFGSRENIL 427 Query: 413 EKLRKWKV 420 E +R++K Sbjct: 428 EAVRRFKE 435 >3EZS-A nrPDB Length = 376 Score = 203 bits (515), Expect = 2e-52, Method: Composition-based stats. Identities = 72/405 (17%), Positives = 142/405 (35%), Gaps = 56/405 (13%) Query: 23 KLASEHDVVNLGQGFPDFPPPDFAVEAFQHAVSGDFMLNQYTKTFGYPPLTKILASFFGE 82 ++ + ++LG G P F P F +A ++ LN Y K+ L FF Sbjct: 18 EITPKKRGLDLGIGEPQFETPKFIQDALKNHTHS---LNIYPKSAFEESLRAAQRGFFKR 74 Query: 83 LLGQEIDPLRNVLVTVGGYGALFT--AFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPV 140 E+ ++ T+G LF +F + + PF+ YE + + Sbjct: 75 RFKIELK-ENELISTLGSREVLFNFPSFVLFDYQNPTIAYPNPFYQIYEGAAKFIKAKSL 133 Query: 141 FVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVA 200 + L +++ E + ++LN+PNNP G+ S EEL Sbjct: 134 LMPL----------TKENDFTPSLNEKELQ---EVDLVILNSPNNPTGRTLSLEELISWV 180 Query: 201 SLCQQHDVVCITDEVYQWMVYDGHQHISIASL-----PGMWERTLTIGSAGKTFSATGWK 255 L +HD + I DE Y + Y+ S+ ++ L I S K SA G + Sbjct: 181 KLALKHDFILINDECYSEI-YENTPPPSLLEACMLAGNEAFKNVLVIHSLSKRSSAPGLR 239 Query: 256 VGWVLGPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFPQAMQR 315 G++ G +++ + + Q A ++ ++ + F Sbjct: 240 SGFIAGDSRLLEKYKAFRAYLGYTSANAIQKASEAAWLDDR--------HAEFFRNIYAN 291 Query: 316 CRDHMIRSLQSVGLKPIIPQGSYFLITDISDFKRKMPDLPGAVDEPYDRRFVKWMIKNKG 375 + ++ + P S+++ + + + F K + +N+G Sbjct: 292 NLKLARKIFKNTLIYP----YSFYVYLPVQNGEN----------------FAKTLYQNEG 331 Query: 376 LVAIPVSIFYSVPHQKHFDHYIRFCFVKDEATLQAMDEKLRKWKV 420 ++ +P + Y+R V D L+ E + ++ Sbjct: 332 IITLPALYLG---RNRIGADYVRLALVYDTPLLEKPLEIIETYRE 373 >2ZYJ-A nrPDB Length = 397 Score = 202 bits (514), Expect = 2e-52, Method: Composition-based stats. Identities = 72/415 (17%), Positives = 143/415 (34%), Gaps = 51/415 (12%) Query: 12 GIDYNPWVEFVKLASEHDVVNLGQGFPD---FPPPDFAVEAFQHAVSGDFMLNQYTKTFG 68 I + E +KL +++ G P FP + A A + + QY+ T G Sbjct: 16 RIQASTIRELLKLTQRPGILSFAGGLPAPELFPKEEAAEAAARILREKGEVALQYSPTEG 75 Query: 69 YPPLTKILASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCY 128 Y PL +A + G VL+T G AL + +DEG V++ P + Sbjct: 76 YAPLRAFVAEWIGVR-------PEEVLITTGSQQALDLVGKVFLDEGSPVLLEAPSYMGA 128 Query: 129 EPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLG 188 + G R + V LD +E K ++ + NP G Sbjct: 129 IQAFRLQGPRFLTVPAGEEGPD-----------LDALEEVLKRERPRFLYLIPSFQNPTG 177 Query: 189 KVFSREELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGM--WERTLTIGSAG 246 + + + + + +V + D+ Y+ + + + S+ L + + +GS Sbjct: 178 GLTPLPARKRLLQMVMERGLVVVEDDAYRELYFGEARLPSLFELAREAGYPGVIYLGSFS 237 Query: 247 KTFSATGWKVGWVLGPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYF 306 K S G +V + + ++ L Q + H P +Q V +LL S Sbjct: 238 KVLS-PGLRVAFAVAHPEALQKLVQAKQGADLHTPMLNQMLV------HELLKEGFSERL 290 Query: 307 VQFPQAMQRCRDHMIRSLQSV---GLKPIIPQGSYFLITDISDFKRKMPDLPGAVDEPYD 363 + + + M+ +L ++ P+G F+ ++ A++E Sbjct: 291 ERVRRVYREKAQAMLHALDREVPKEVRYTRPKGGMFVWMELPKGLSAEGLFRRALEEN-- 348 Query: 364 RRFVKWMIKNKGLVAIPVSIFYSVPHQKHFDHYIRFCFVK-DEATLQAMDEKLRK 417 + +P F++ ++ +R + D + +L + Sbjct: 349 ------------VAFVPGGPFFANGG---GENTLRLSYATLDREGIAEGVRRLGR 388 >3FDB-A nrPDB Length = 377 Score = 197 bits (501), Expect = 7e-51, Method: Composition-based stats. Identities = 63/397 (15%), Positives = 132/397 (33%), Gaps = 53/397 (13%) Query: 27 EHDVVNLGQGFPDFPPPDFAVEAFQHAVSGDFMLNQYTKTFGYPP----LTKILASFFGE 82 V+ L DF ++A AV + FGY P L++ A F+ + Sbjct: 22 GQGVLPLWVAESDFSTCPAVLQAITDAVQRE--------AFGYQPDGSLLSQATAEFYAD 73 Query: 83 LLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPVFV 142 G + P + L+ A +VI+ P + + + +F+ Sbjct: 74 RYGYQARP-EWIFPIPDVVRGLYIAIDHFTPAQSKVIVPTPAYPPFFHLLSATQREGIFI 132 Query: 143 SLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASL 202 G ++ ++ F + ++++L P NPLG VF+ E L + L Sbjct: 133 DATGG--------------INLHDVEKGFQAGARSILLCNPYNPLGMVFAPEWLNELCDL 178 Query: 203 CQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTIGSAGKTFSATGWKVGWVLGP 262 ++D + DE++ +V+DG ++ +TI + K ++ G K ++ Sbjct: 179 AHRYDARVLVDEIHAPLVFDGQHTVAAGVSDTAASVCITITAPSKAWNIAGLKCAQIIFS 238 Query: 263 DHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFPQAMQRCRDHMIR 322 + ++ P A + +R + + Q ++ D ++ Sbjct: 239 NPSDA------EHWQQLSPVIKDGASTLGLIAAEAAYRYGTDFLNQEVAYLKNNHDFLLH 292 Query: 323 SLQS--VGLKPIIPQGSYFLITDISDFKRKMPDLPGAVDEPYDRRFVKWMIKNKGLVAIP 380 + G K Q +Y + D D + ++ I+ + Sbjct: 293 EIPKRIPGAKITPMQATYLMWIDFRDTTIEGSP-------------SEFFIEKAKVAMND 339 Query: 381 VSIFYSVPHQKHFDHYIRFCFVKDEATLQAMDEKLRK 417 + F + R F L+ +++ K Sbjct: 340 GAWFGED-----GTGFCRLNFATSREVLEEAIDRMAK 371 >4GDY-A nrPDB Length = 439 Score = 196 bits (498), Expect = 1e-50, Method: Composition-based stats. Identities = 77/419 (18%), Positives = 150/419 (35%), Gaps = 48/419 (11%) Query: 28 HDVVNLGQGFPD-----FPPPDFAVEAFQHAVSGDFMLN---QYTKTFGYPPLTKILASF 79 +++L G P+ F VE + G+ M+ QY+ + G P L L Sbjct: 31 KSMISLAGGLPNPNMFPFKTAVITVENGKTIQFGEEMMKRALQYSPSAGIPELLSWLKQL 90 Query: 80 FGELLG---QEIDPLR---NVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTM 133 +L P + ++ VT G L F+ +++ GD V++ EP + Sbjct: 91 QIKLHNPPTIHYPPSQGQMDLCVTSGSQQGLCKVFEMIINPGDNVLLDEPAYSGTLQSLH 150 Query: 134 MAGGRPVFV-SLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFS 192 G + V S + G + + S W+ + + K T + + NNP G + Sbjct: 151 PLGCNIINVASDESGIVPDSLRDILSRWKPEDAKNPQKNTPKF-LYTVPNGNNPTGNSLT 209 Query: 193 REELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTIGSAGKTFSAT 252 E + + L +++D + I D+ Y ++ ++ + + S+ + R + S K S + Sbjct: 210 SERKKEIYELARKYDFLIIEDDPYYFLQFNSGRVPTFLSMD-VDGRVIRADSFSKIIS-S 267 Query: 253 GWKVGWVLGPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLL-----FRQPSSYFV 307 G ++G++ GP +++ + Q S H T +Q +++ + ++ Sbjct: 268 GLRIGFLTGPKPLIERVILHIQVSTLHPSTFNQLMISQLLHEWGEEGFMAHVDRVIDFYS 327 Query: 308 QFPQAMQRCRDHMIRSLQSVGLKPIIPQGSYFLITDISDFKRKMPDLPGAVDEPYDRRFV 367 A+ D + L +P FL + V Sbjct: 328 NQKDAILAAADKWLTGLAE----WHVPAAGMFLWIKVKGIND-----------------V 366 Query: 368 KWMIKNK----GLVAIPVSIFYSVPHQKHFDHYIRFCFVKDEATLQAMDEKLRKWKVEL 422 K +I+ K G++ +P + FY F E A + K L Sbjct: 367 KELIEEKAVKMGVLMLPGNAFYVDSSAPSPYLRASFSSASPEQMDVAFQVLAQLIKESL 425 >1C7O-A nrPDB Length = 399 Score = 195 bits (495), Expect = 4e-50, Method: Composition-based stats. Identities = 65/394 (16%), Positives = 141/394 (35%), Gaps = 42/394 (10%) Query: 29 DVVNLGQGFPDFPPPDFAVEAFQHAVSGDFMLNQYTKTFGYPPLTKILASFFGELLGQEI 88 +VV L +F P +E + + D + YT K + + + +I Sbjct: 32 EVVPLSVADMEFKNPPELIEGLKKYL--DETVLGYTGPT--EEYKKTVKKWMKDRHQWDI 87 Query: 89 DPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPGP 148 ++ T G A+F A + GD VIII P + + + + L Sbjct: 88 Q-TDWIINTAGVVPAVFNAVREFTKPGDGVIIITPVYYPFFMAIKNQERKIIECEL---- 142 Query: 149 IQNGELGSSSNWQLDPMELAGKFTSRT-KALVLNTPNNPLGKVFSREELELVASLCQQHD 207 L + +D +L + KAL+ +P+NP+G+V+ ++EL+ + + + D Sbjct: 143 -----LEKDGYYTIDFQKLEKLSKDKNNKALLFCSPHNPVGRVWKKDELQKIKDIVLKSD 197 Query: 208 VVCITDEVYQWMVYDGHQHISIASLPG-MWERTLTIGSAGKTFSATGWKVG-WVLGPDHI 265 ++ +DE++ ++ G++H S+ + ++T+T + KTF+ G + ++ I Sbjct: 198 LMLWSDEIHFDLIMPGYEHTVFQSIDEQLADKTITFTAPSKTFNIAGMGMSNIIIKNPDI 257 Query: 266 MKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFPQAMQRCRDHMIRSLQ 325 + + T E + +++ + + + + + + + Sbjct: 258 RERFTKSRDATSGMPFTTLGYKACE------ICYKECGKWLDGCIKVIDKNQRIVKDFFE 311 Query: 326 SVGLKPIIP--QGSYFLITDISDFKRKMPDLPGAVDEPYDRRFVKWMIKNKGLVAIPVSI 383 + P +G+Y D K + + F + I Sbjct: 312 VNHPEIKAPLIEGTYLQWIDFRALKMDHKAMEEFMIHKAQIFFDE------------GYI 359 Query: 384 FYSVPHQKHFDHYIRFCFVKDEATLQAMDEKLRK 417 F + R + +Q E+L K Sbjct: 360 FGDG-----GIGFERINLAAPSSVIQESLERLNK 388 >3IF2-A nrPDB Length = 444 Score = 188 bits (476), Expect = 5e-48, Method: Composition-based stats. Identities = 76/386 (19%), Positives = 134/386 (34%), Gaps = 50/386 (12%) Query: 63 YTKTFGYPPLTKILASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQ----ALVDEG--- 115 Y+ G L FF + N+ +T G A F F A V+E Sbjct: 79 YSNPQGDSAFIDALVGFFNRHYDWNLT-SENIALTNGSQNAFFYLFNLFGGAFVNEHSQD 137 Query: 116 ------DEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQL--DPMEL 167 D+ I++ P Y + + F ++ P + G ++ D L Sbjct: 138 KESKSVDKSILL-PLTPEYIGYSDVHVEGQHFAAVLPHIDEVTHDGEEGFFKYRVDFEAL 196 Query: 168 A---GKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQQHDVVCITDEVYQW----MV 220 R A+ + P NP G V + EE+ +A + +++D+ I D Y ++ Sbjct: 197 ENLPALKEGRIGAICCSRPTNPTGNVLTDEEMAHLAEIAKRYDIPLIIDNAYGMPFPNII 256 Query: 221 YDGHQHISIASLPGMWERTLTIGSAGKTFSATGWKVGWVLGPDHIMKHLRTVHQNSVFHC 280 Y T+ S K G + G ++ +++ + ++ Sbjct: 257 YSDAH-------LNWDNNTILCFSLSK-IGLPGMRTGIIVADAKVIEAVSAMNAVVNL-A 307 Query: 281 PTQSQAAVAESFEREQLLFRQPSSYFVQFPQAMQR-CRDHMIRSLQSVGLKPIIPQGSYF 339 PT+ AA+A + + + F Q + ++L L P+G+ F Sbjct: 308 PTRFGAAIATPLVANDRIKQLSDNEIKPFYQKQATLAVKLLKQALGDYPLMIHKPEGAIF 367 Query: 340 LITDISDFKRKMPDLPGAVDEPYDRRFVKWMIKNKGLVAIPVSIFY---SVPHQKHFDHY 396 L DLP + + Y+R +K KG + +P F+ V +H Sbjct: 368 LWL-------WFKDLPISTLDLYER------LKAKGTLIVPSEYFFPGVDVSDYQHAHEC 414 Query: 397 IRFCFVKDEATLQAMDEKLRKWKVEL 422 IR DE TL + + + EL Sbjct: 415 IRMSIAADEQTLIDGIKVIGEVVREL 440 >3TCM-A nrPDB Length = 500 Score = 184 bits (466), Expect = 8e-47, Method: Composition-based stats. Identities = 70/381 (18%), Positives = 140/381 (36%), Gaps = 41/381 (10%) Query: 63 YTKTFGYPPLTKILASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQALV-DEGDEVIII 121 Y+ + G L +AS G + ++ +T G + Q L+ +E D +++ Sbjct: 130 YSHSQGIHGLRDAIASGIASRDGFPANA-DDIFLTDGASPGVHLMMQLLIRNEKDGILVP 188 Query: 122 EPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTS------RT 175 P + Y + GG V L S+ W L+ ++ + Sbjct: 189 IPQYPLYSASIALHGGALVPYYLN----------ESTGWGLETSDVKKQLEDARSRGINV 238 Query: 176 KALVLNTPNNPLGKVFSREELELVASLCQQHDVVCITDEVYQWMVY----DGHQHISIAS 231 +ALV+ P NP G+V + E + C+ +V + DEVYQ +Y H I Sbjct: 239 RALVVINPGNPTGQVLAEENQYDIVKFCKNEGLVLLADEVYQENIYVDNKKFHSFKKIVR 298 Query: 232 LPGMWERTLTIGSA---GK-TFSATGWKVGW---VLGPDHIMKHLRTVHQ-NSVFHCPTQ 283 G E L + S K + G + G+ + + + + N + Q Sbjct: 299 SLGYGEEDLPLVSYQSVSKGYYGECGKRGGYFEITGFSAPVREQIYKIASVNLCSNITGQ 358 Query: 284 SQAAVA----ESFEREQLLFRQPSSYFVQFPQAMQRCRDHMIRSLQSVGLKPIIPQGSYF 339 A++ ++ + ++ + + +H L+ G+ +G+ + Sbjct: 359 ILASLVMNPPKASDESYASYKAEKDGILASLARRAKALEHAFNKLE--GITCNEAEGAMY 416 Query: 340 LITDISDFKRKMPDLPGAVDEPYDRRFVKWMIKNKGLVAIPVSIFYSVPHQKHFDHYIRF 399 + I +K + A ++ D + ++++ G+V +P S F VP HF R Sbjct: 417 VFPQIC-LPQKAIEAAKAANKAPDAFYALRLLESTGIVVVPGSGFGQVPGTWHF----RC 471 Query: 400 CFVKDEATLQAMDEKLRKWKV 420 + E + A+ + + Sbjct: 472 TILPQEDKIPAVISRFTVFHE 492 >4M2J-A nrPDB Length = 406 Score = 183 bits (464), Expect = 1e-46, Method: Composition-based stats. Identities = 63/357 (17%), Positives = 124/357 (34%), Gaps = 41/357 (11%) Query: 64 TKTFGYPPLTKILASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEP 123 + + G + + +A + G + D VLVT G A+ AL+ GD V++ E Sbjct: 81 SVSQGGEGVRRAIADRYA---GGDAD---RVLVTHGSSEAIALTLNALLHRGDRVVVQEG 134 Query: 124 FFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTP 183 + AG + + + ++DP LAG T T A+++N P Sbjct: 135 IYHSLGHYPRAAGCDVAVLPGRAV----------RDGEIDPDVLAGLVTPGTAAVIVNFP 184 Query: 184 NNPLGKVFSREELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTIG 243 +NP G S + L + V + D + H+ +A T++ G Sbjct: 185 HNPTGVTLSPQGLRALKERTAATGAVLVWDAATAEIA---HRWEVLADPGADGGDTVSYG 241 Query: 244 SAGKTFSATGWKVGWVLGPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPS 303 + KTF G +VGW + P ++ + + + + R Sbjct: 242 TLSKTFGLPGLRVGWAVAPKELLTATFPLRDRTTLFLSPLVELVA-------ERAVRHAD 294 Query: 304 SYFVQFPQAMQRCRDHMIRSLQSVG--LKPIIPQGSYFLITDISDFKRKMPDLPGAVDEP 361 + H+ + + ++ P+G + + +R P V+ Sbjct: 295 ELIGARAAEARHNLAHLTGWMAAHEELVRWTPPEGGVCALPVFRELERAAA-GPQEVE-- 351 Query: 362 YDRRFVKWMIKNKGLVAIPVSIFYSVPHQKHFDHYIRFCFVKDEATLQAMDEKLRKW 418 RF +++ + +P + F + H R F + +A + L ++ Sbjct: 352 ---RFCLELLERHRTLLVPGTAFGA-------PHGARLGFGGPQEDFRAGLDGLSRF 398 >3DZZ-A nrPDB Length = 391 Score = 182 bits (461), Expect = 2e-46, Method: Composition-based stats. Identities = 59/399 (14%), Positives = 140/399 (35%), Gaps = 48/399 (12%) Query: 27 EHDVVNLGQGFPDFPPPDFAVEAFQHAVSGDFMLNQYTKTFGYP----PLTKILASFFGE 82 + + + DF + + + + FGY K +A + E Sbjct: 26 KEKELPMWIAEMDFKIAPEIMASMEEKLKVA--------AFGYESVPAEYYKAVADW-EE 76 Query: 83 LLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPVFV 142 + + + G A+ + GD++++ EP ++ + + G R + Sbjct: 77 IEHRARPKEDWCVFASGVVPAISAMVRQFTSPGDQILVQEPVYNMFYSVIEGNGRRVISS 136 Query: 143 SLKPGPIQNGELGSSSNWQLDPMELAGKF-TSRTKALVLNTPNNPLGKVFSREELELVAS 201 L + +S + ++ +L K T + +V P+NP+G +S EE++ +A Sbjct: 137 DL---------IYENSKYSVNWADLEEKLATPSVRMMVFCNPHNPIGYAWSEEEVKRIAE 187 Query: 202 LCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTLT-IGSAGKTFSATGWKVGWVL 260 LC +H V+ I+DE++ +V ++ + + + S KTF+ + Sbjct: 188 LCAKHQVLLISDEIHGDLVLTDEDITPAFTVDWDAKNWVVSLISPSKTFNLAALHAACAI 247 Query: 261 GPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFPQAMQRCRDHM 320 P+ ++ F + + + + + + Q ++ + Sbjct: 248 IPNPDLRA----RAEESFFLAGIGEPNLLAI-PAAIAAYEEGHDWLRELKQVLRDNFAYA 302 Query: 321 IRSL--QSVGLKPIIPQGSYFLITDISDFKRKMPDLPGAVDEPYDRRFVKWMIKNKGLVA 378 L + +K + SY DIS D F K++ + GL+ Sbjct: 303 REFLAKEVPEVKVLDSNASYLAWVDISALGMNAED------------FCKYLREKTGLII 350 Query: 379 IPVSIFYSVPHQKHFDHYIRFCFVKDEATLQAMDEKLRK 417 + + + + ++R + + ++L++ Sbjct: 351 SAGNGY-----RGNGHEFVRINLACPKELVIDGMQRLKQ 384 >4R2N-A nrPDB Length = 367 Score = 175 bits (442), Expect = 4e-44, Method: Composition-based stats. Identities = 72/394 (18%), Positives = 124/394 (31%), Gaps = 63/394 (15%) Query: 28 HDVVNLGQGFPDFPPPDFAVEAFQHAVSGDFMLNQYTKTFGYPPLTKILASFFGELLGQE 87 + L F P A A +N+Y G L LA LG + Sbjct: 23 PGAIKLASNETVFGPLPSVRAAIDRATD---TVNRYPDN-GCVQLKAALA----RHLGPD 74 Query: 88 IDPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPG 147 P +V V G Q GDEV+ F+ Y P +AG P+ V L Sbjct: 75 FAP-EHVAVGCGSVSLCQQLVQVTASVGDEVVFGWRSFELYPPQVRVAGAIPIQVPL--- 130 Query: 148 PIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQQHD 207 ++ D + T RT+ + + PNNP V + L H Sbjct: 131 ----------TDHTFDLYAMLATVTDRTRLIFVCNPNNPTSTVVGPDALARFVEAVPAH- 179 Query: 208 VVCITDEVYQWMVYDGHQHISIASLPGMWERTLTIGSAGKTFSATGWKVGWVLGPDHIMK 267 ++ DE Y + DG + S+ L + + + K + G ++G+ +G ++ Sbjct: 180 ILIAIDEAYVEYIRDGMRPDSL-GLVRAHNNVVVLRTFSKAYGLAGLRIGYAIGHPDVIT 238 Query: 268 HLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFPQAMQRCRDHMIRSLQSV 327 L V F + QAA S + L + + + R + L++ Sbjct: 239 ALDKV--YVPFTVSSIGQAAAIASLDAADELLARTDTVVAE--------RARVSAELRAA 288 Query: 328 GLKPIIPQGSYFLITDISDFKRKMPDLPGAVDEPYDRRFVKWMIKNKGLVAIPVSIFYSV 387 G + P + F+ + + + + +V P Sbjct: 289 GF-TLPPSQANFVWLPLGSRTQDFVEQA----------------ADARIVVRP------- 324 Query: 388 PHQKHFDHYIRFCFVKDEATLQAMDEKLRKWKVE 421 + +R E A R+W+ + Sbjct: 325 ----YGTDGVRVTVAAPEEN-DAFLRFARRWRSD 353 >3HDO-A nrPDB Length = 360 Score = 171 bits (434), Expect = 4e-43, Method: Composition-based stats. Identities = 60/337 (17%), Positives = 109/337 (32%), Gaps = 43/337 (12%) Query: 37 FPDFPPPDFAVEAFQHAVSGDFMLNQYTKTFGYPPLTKILASFFGELLGQEIDPLRNVLV 96 P P P+ + L Y ++ L GEL G + +++ Sbjct: 36 NPYPPSPEVVKAILEELGPDGAALRIYPSAS-----SQKLREVAGELYGFDP---SWIIM 87 Query: 97 TVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGS 156 G L +A EG+E+ + P + Y + + G R L G Sbjct: 88 ANGSDEVLNNLIRAFAAEGEEIGYVHPSYSYYGTLAEVQGARVRTFGLTGDFRIAGFPER 147 Query: 157 SSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQQHDVVCITDEVY 216 K L TPN PLG F E ++ +A C + + DE Y Sbjct: 148 YEG----------------KVFFLTTPNAPLGPSFPLEYIDELARRCAG---MLVLDETY 188 Query: 217 QWMVYDGHQHISIASLPGMWERTLTIGSAGKTFSATGWKVGWVLGPDHIMKHLRTVHQNS 276 L E + + K++S G ++G + ++ L + + Sbjct: 189 AEFAESNA-----LELVRRHENVVVTRTLSKSYSLAGMRIGLAIARPEVIAALDKIRDH- 242 Query: 277 VFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFPQAMQRCRDHMIRSLQSVGLKPIIPQG 336 ++ +QAA + +Y + + ++ R+ L+S+G I QG Sbjct: 243 -YNLDRLAQAACVAALRD--------QAYLSECCRRIRETREWFTTELRSIGYDVIPSQG 293 Query: 337 SYFLITDISDFKRKMPDLPGAVDEPYDRRFVKWMIKN 373 + +L D K + R F ++ + Sbjct: 294 N-YLFATPPDRDGKRVYDGLYARKVLVRHFSDPLLAH 329 >1IJI-A nrPDB Length = 356 Score = 166 bits (420), Expect = 2e-41, Method: Composition-based stats. Identities = 57/301 (18%), Positives = 108/301 (35%), Gaps = 34/301 (11%) Query: 44 DFAVEAFQHAVSGDFMLNQYTKTFGYPPLT-KILASFFGELLGQEIDPLRNVLVTVGGYG 102 D + A ++ + +F L Q T YP K + + + G + VLV+ G Sbjct: 31 DVWLNANEYPTAVEFQLTQQTLNR-YPECQPKAVIENYAQYAGVKP---EQVLVSRGADE 86 Query: 103 ALFTAFQALVDEG-DEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQ 161 + +A + G D ++ P + Y G V NWQ Sbjct: 87 GIELLIRAFCEPGKDAILYCPPTYGMYSVSAETIGVECRTVPTL------------DNWQ 134 Query: 162 LDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQQHDVVCITDEVYQWMVY 221 LD ++ K K + + +PNNP G++ + ++ + L + + + DE Y Sbjct: 135 LDLQGISDKL-DGVKVVYVCSPNNPTGQLINPQDFRTLLELTRGK-AIVVADEAYIEF-- 190 Query: 222 DGHQHISIASLPGMWERTLTIGSAGKTFSATGWKVGWVLGPDHIMKHLRTVHQNSVFHCP 281 S+A + + + K F+ G + G+ L + ++ L V P Sbjct: 191 --CPQASLAGWLAEYPHLAILRTLSKAFALAGLRCGFTLANEEVINLLMKVIAPYPLSTP 248 Query: 282 TQSQAAVAESFEREQLLFRQPSSYFVQFPQAMQRCRDHMIRSLQSVGL--KPIIPQGSYF 339 AA A L Q + + R+++I +L+ + + + +Y Sbjct: 249 VADIAAQA--------LSPQGIVAMRERVAQIIAEREYLIAALKEIPCVEQVFDSETNYI 300 Query: 340 L 340 L Sbjct: 301 L 301 >6HNV-A nrPDB Length = 524 Score = 164 bits (414), Expect = 8e-41, Method: Composition-based stats. Identities = 70/392 (17%), Positives = 134/392 (34%), Gaps = 50/392 (12%) Query: 62 QYTKTFGYPPLTKILASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVIII 121 QY G+ PL + F D NV +T G L A +D+GD +++ Sbjct: 129 QYAAVEGHAPLLQFARDFIIRTHKPNYD-DWNVFITTGASDGLNKAADVFLDDGDVILVE 187 Query: 122 EPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALV-L 180 E F + + AG + V V + +G + L+ E + KAL + Sbjct: 188 EFTFSPFLRFSDNAGAKAVPVKINFDNDSDGIDLTQFVDLLENWEKHYPNLPKPKALYTI 247 Query: 181 NTPNNPLGKVFSREELELVASLCQQHDVVCITDEVYQWM--------------------- 219 T NP G S E + + L ++D I D+ Y ++ Sbjct: 248 ATGQNPTGFTQSLEFRKKIYDLAVKYDFAIIEDDPYGYLTLPKYEKPNIGGSGSGNNELK 307 Query: 220 -------VYDGHQHISIASLPGMWERTLTIGSAGKTFSATGWKVGWVLGPDHIMKHLRTV 272 H S L R L + + K F+ G ++G+++G ++ ++ Sbjct: 308 NDLEIDDYLKNHLTPSYLELDTTG-RVLRVETFSKLFA-PGLRLGFIVGHKEVIDAVKNY 365 Query: 273 HQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFPQAMQRCRDHMIRSLQSVG---- 328 +Q V + + ++ +D ++ S+ Sbjct: 366 SDVVNRGASGLTQTIVNNVIQENFKGVDGWLEWILKMRLNYSYRKDLLLYSIFESQAYKK 425 Query: 329 --LKPIIPQGSYFLITDISDFKRKMPDLPGAVDEPYDRRFVKWMIKNKGLVAIPV-SIFY 385 + I P+ F+ I +LP VD + + W + + G++ +P ++ Sbjct: 426 GYVDVIDPKAGMFVTFKI--------NLPKDVDVLQKMKLLLWKLISYGILVVPGYNMTV 477 Query: 386 SVPHQKHFDHYIRFCFV---KDEATLQAMDEK 414 + K ++ R C+ DE L++ Sbjct: 478 DLEFSKDRSNFFRLCYALANNDEEILESGKRL 509 >2ZY3-A nrPDB Length = 546 Score = 163 bits (411), Expect = 2e-40, Method: Composition-based stats. Identities = 88/427 (20%), Positives = 140/427 (32%), Gaps = 77/427 (18%) Query: 49 AFQHAVSGDFMLNQYTKTFGYPPLTKILASFFG-ELLGQEIDPLR--NVLVTVGGYGALF 105 AF H + + Y +++ + + +G + P N+ GG A+ Sbjct: 120 AFLHEMVDGILGCNYPVPPRMLNISEKIVRQYIIREMGADAIPSESVNLFAVEGGTAAMA 179 Query: 106 TAFQAL-----VDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNW 160 F++L + GD+V I P F Y + +A V++ P S NW Sbjct: 180 YIFESLKLNGLLKAGDKVAIGMPVFTPYIEIPELAQYALEEVAINADP--------SLNW 231 Query: 161 QLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQQH--DVVCITDEVYQW 218 Q EL K P+NP + LE V ++ +H D++ +TD+VY Sbjct: 232 QYPDSELDKLKDPAIKIFFCVNPSNPPSVKMDQRSLERVRNIVAEHRPDLMILTDDVYGT 291 Query: 219 MVYDGHQHISIASLPGMWERTLTIGSAGKTFSATGWKVGWVLGP---------------- 262 D +I E TL + S K F ATGW++G V Sbjct: 292 FADDFQSLFAICP-----ENTLLVYSFSKYFGATGWRLGVVAAHQQNVFDLALDKLQESE 346 Query: 263 ---------------------DHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQ 301 D ++ R V N T Q V + L + Sbjct: 347 KVALDHRYRSLLPDVRSLKFIDRLVADSRAVALNHTAGLSTPQQ--VQMALFSLFALMDE 404 Query: 302 PSSYFVQFPQAMQRCRDHMIRSLQSVGLKPIIPQGS--YFLITDISDFKRKM---PDLPG 356 Y Q ++R + R L G+ P+ + + Y+ + D+ D K+ Sbjct: 405 ADEYKHTLKQLIRRRETTLYREL---GMPPLRDENAVDYYTLIDLQDVTAKLYGEAFSEW 461 Query: 357 AVDEPYDRRFVKWMIKNKGLVAIPVSIFYSVPHQKHFDHYIRFCFVKDEATLQAMD-EKL 415 AV + + + G+V +P F S R A L Sbjct: 462 AVKQSSTGDMLFRIADETGIVLLPGRGFGSNRPSG------RASLANLNEYEYAAIGRAL 515 Query: 416 RKWKVEL 422 RK EL Sbjct: 516 RKMADEL 522 >3G0T-A nrPDB Length = 437 Score = 161 bits (406), Expect = 7e-40, Method: Composition-based stats. Identities = 66/392 (16%), Positives = 124/392 (31%), Gaps = 47/392 (11%) Query: 14 DYNPWVEFVKLASEHDVVNLGQGFPDFPPPDFAVEA-FQHAVSGDFMLNQYTKTFGYPPL 72 D V ++ A+ + G P P P +E Q G + + Y G P L Sbjct: 30 DLVALVTNLEKATGTKFCRMEMGVPGLPAPQIGIETEIQKLREG--VASIYPNLDGLPEL 87 Query: 73 TKILASFFGELLGQEIDPLRNVLVTVGGYGALFTAF----QALVDEGDEVIIIEPFFDCY 128 + + F + +I P R + TVG F +F + + + I+P F+ Sbjct: 88 KQEASRFAKLFVNIDI-PARACVPTVGSMQGCFVSFLVANRTHKNREYGTLFIDPGFNLN 146 Query: 129 EPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLG 188 + + G + L G +L+ G+F S ++ + PNNP Sbjct: 147 KLQCRILGQKFESFDL------FEYRGEKLREKLESYLQTGQFCS----IIYSNPNNPTW 196 Query: 189 KVFSREELELVASLCQQHDVVCITDEVYQWMVYD-----GHQHISIASLPGMWERTLTIG 243 + + EEL ++ L +HDV+ I D Y M + + + S+ + + Sbjct: 197 QCMTDEELRIIGELATKHDVIVIEDLAYFGMDFRKDYSHPGEPLYQPSVANYTDNYILAL 256 Query: 244 SAGKTFSATGWKVGWVLGPDHIMKH------------------LRTVHQNSVFHCPTQSQ 285 S+ K FS G ++G ++ + + + +Q Sbjct: 257 SSSKAFSYAGQRIGVLMISGKLYEREYPDLEESFGRLRFGEALSSSALYALSSGATHSAQ 316 Query: 286 AAVAESFEREQLLFRQPSSYFVQFPQAMQRCRDHMIRSLQSVGLKPIIPQGSYFLITD-- 343 +A + F R M + G + + + D Sbjct: 317 WGMAAMLK----ACNDGEYNFRDSVIEYGRKARIMKKMFLDNGFNIVYDKDGNEPLADGF 372 Query: 344 ISDFKRKMPDLPGAVDEPYDRRFVKWMIKNKG 375 K D +++ +K G Sbjct: 373 YFTVGYKGMDSSKLIEKFVRYGMCAITLKTTG 404 >2ZY2-A nrPDB Length = 544 Score = 161 bits (406), Expect = 7e-40, Method: Composition-based stats. Identities = 68/385 (17%), Positives = 127/385 (32%), Gaps = 92/385 (23%) Query: 49 AFQHAVSGDFMLNQYTKTFGYPPLTKILASFF--GELLGQEIDPLR-NVLVTVGGYGALF 105 AF H + + Y +++ + + E+ G + P ++ GG A+ Sbjct: 119 AFLHEMVDGILGCNYPVPPRMLTVSEQIVRQYIVREMAGGAVPPESVDLFAVEGGTAAMA 178 Query: 106 TAFQAL-----VDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNW 160 F++L + GD+V I P F Y + +A V + P + W Sbjct: 179 YIFESLRISGLLKAGDKVAIGMPVFTPYIEIPELAQYDLKEVPIHADP--------DNGW 230 Query: 161 QLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQQH--DVVCITDEVYQW 218 Q EL K P+NP + L+ V ++ + D++ +TD+VY Sbjct: 231 QYSDAELDKLKDPDVKIFFCVNPSNPPSVKMDQRSLDRVRAIVAEQRPDLLILTDDVYGT 290 Query: 219 MVYDGHQHISIASLPGMWERTLTIGSAGKTFSATGWKVGWVLGPDHIMKHLRTVHQNSVF 278 + S+ TL + S K F ATGW++G + Sbjct: 291 FADEFQSLFSVCP-----RNTLLVYSFSKYFGATGWRLGVIAAHKD-------------- 331 Query: 279 HCPTQSQAAVAESFEREQLLFRQPSSYFVQFPQAMQRCRDHMIRSLQSVGLKPIIPQGSY 338 Q P++ ++ DH RSL Sbjct: 332 ---------------------NVFDHALSQLPESAKKALDHRYRSL-------------- 356 Query: 339 FLITDISDFKRKMPDLPGAVDEPYDRRFVKWMIKNKGLVAIPVSIFYSVPHQKHFDHYIR 398 + D+ +F+ ++ + +VA+ + S P Q + Sbjct: 357 --LPDVRSL-----------------KFIDRLVADSRVVALNHTAGLSTPQQVQMVLFSL 397 Query: 399 FCFVKD-EATLQAMDEKLRKWKVEL 422 F + + +A QA+ + +R+ + L Sbjct: 398 FALMDEADAYKQALKQLIRRREATL 422 >3IHJ-A nrPDB Length = 498 Score = 159 bits (402), Expect = 2e-39, Method: Composition-based stats. Identities = 76/415 (18%), Positives = 142/415 (34%), Gaps = 51/415 (12%) Query: 38 PDFPPPDFAVEAFQHAVS--GDFMLNQYTKTFGYPPLTKILASFFGELLGQEIDPLRNVL 95 P F P+ A + + + G L Y+ + G + + +A++ G N+ Sbjct: 100 PSF--PEDAKKRARRILQACGGNSLGSYSASQGVNCIREDVAAYITRRDGGVPADPDNIY 157 Query: 96 VTVGGYGALFTAFQALVDEGDE----VIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPIQN 151 +T G + T + LV G + V+I P + Y + V L Sbjct: 158 LTTGASDGISTILKILVSGGGKSRTGVMIPIPQYPLYSAVISELDAIQVNYYLD------ 211 Query: 152 GELGSSSNWQLDPMELAGKFTSRT-----KALVLNTPNNPLGKVFSREELELVASLCQQH 206 + W L+ EL K L + P NP G+V SR+ +E V + Sbjct: 212 ----EENCWALNVNELRRAVQEAKDHCDPKVLCIINPGNPTGQVQSRKCIEDVIHFAWEE 267 Query: 207 DVVCITDEVYQWMVYD-GHQHISI----ASLPGMWERTLTIGSA---GKTF-SATGWKVG 257 + + DEVYQ VY + S + + + + S K + G++ G Sbjct: 268 KLFLLADEVYQDNVYSPDCRFHSFKKVLYEMGPEYSSNVELASFHSTSKGYMGECGYRGG 327 Query: 258 W---VLGPDHIMKHLRTVHQNSVFHCPTQSQAAV-------AESFEREQLLFRQPSSYFV 307 + + I L + + P QAA+ E + R+ S Sbjct: 328 YMEVINLHPEIKGQLVKL-LSVRLCPPVSGQAAMDIVVNPPVAGEESFEQFSREKESVLG 386 Query: 308 QFPQAMQRCRDHMIRSLQSVGLKPIIPQGSYFLITDISDFKRKMPDLPGAVDEPYDRRFV 367 + + D Q G+ QG+ + I K + A D + Sbjct: 387 NLAKKAKLTEDLFN---QVPGIHCNPLQGAMYAFPRIF-IPAKAVEAAQAHQMAPDMFYC 442 Query: 368 KWMIKNKGLVAIPVSIFYSVPHQKHFDHYIRFCFVKDEATLQAMDEKLRKWKVEL 422 +++ G+ +P S F Q+ ++ R + L+ + +K++ + + Sbjct: 443 MKLLEETGICVVPGSGFG----QREGTYHFRMTILPPVEKLKTVLQKVKDFHINF 493 >3FDD-A nrPDB Length = 533 Score = 158 bits (398), Expect = 6e-39, Method: Composition-based stats. Identities = 81/429 (18%), Positives = 133/429 (31%), Gaps = 81/429 (18%) Query: 49 AFQHAVSGDFMLNQYTKTFGYPPLTKILASFFG-ELLGQEIDPLR--NVLVTVGGYGALF 105 AF H + + Y +++ + + +G + P N+ GG A+ Sbjct: 120 AFLHEMVDGILGCNYPVPPRMLNISEKIVRQYIIREMGADAIPSESVNLFAVEGGTAAMA 179 Query: 106 TAFQA-----LVDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNW 160 F++ L+ GD+V I P F Y + +A V++ P + NW Sbjct: 180 YIFESMKVNGLLKAGDKVAIGMPVFTPYIEIPELAQYALEEVAINADP--------ALNW 231 Query: 161 QLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQQH--DVVCITDEVYQW 218 Q EL K P+NP LE V + +H D++ +TD+VY Sbjct: 232 QYPDSELDKLKDPAIKIFFCVNPSNPPSVKMDERSLERVRKIVAEHRPDLMILTDDVYGT 291 Query: 219 MVYDGHQHISIASLPGMWERTLTIGSAGKTFSATGWKVGWVLGPDHIM------------ 266 +I TL + S K F ATGW++G V + Sbjct: 292 FADGFQSLFAICPA-----NTLLVYSFSKYFGATGWRLGVVAAHKENIFDLALGRLPESE 346 Query: 267 ---------------------------KHLRTVHQNSVFHCPTQSQAAVAESFEREQLLF 299 ++ + P Q Q + F L Sbjct: 347 KTALDDRYRSLLPDVRSLKFLDRLVADSRAVALNHTAGLSTPQQVQMTLFSLF----ALM 402 Query: 300 RQPSSYFVQFPQAMQRCRDHMIRSLQSVGLKPIIPQGS--YFLITDISDFKRKM---PDL 354 + Y Q ++R + R L G P + + Y+ + D+ D K+ Sbjct: 403 DESDQYKHTLKQLIRRREATLYREL---GTPPQRDENAVDYYTLIDLQDVTSKLYGEAFS 459 Query: 355 PGAVDEPYDRRFVKWMIKNKGLVAIPVSIFYSVPHQKHFDHYIRFCFVKDEATLQAMD-E 413 AV + + + G+V +P F S R A Sbjct: 460 KWAVKQSSTGDMLFRIADETGIVLLPGRGFGSDRPSG------RASLANLNEYEYAAIGR 513 Query: 414 KLRKWKVEL 422 LR+ EL Sbjct: 514 ALRQMADEL 522 >3GET-A nrPDB Length = 365 Score = 157 bits (397), Expect = 7e-39, Method: Composition-based stats. Identities = 57/378 (15%), Positives = 125/378 (33%), Gaps = 42/378 (11%) Query: 21 FVKLASEHDVVNLGQGFPDFPPPDFAVEAFQHAVSGDFMLNQYTKTFGYPPLTKILASFF 80 K +V+ L F P A+E + + + L LA + Sbjct: 23 IAKEYGVKEVIKLASNENPFGTPPKAIECLRQNANKAHLY----PDDSMIELKSTLAQKY 78 Query: 81 GELLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPV 140 N+++ G + A + ++ + + F YE G + Sbjct: 79 KVQN-------ENIIIGAGSDQVIEFAIHSKLNSKNAFLQAGVTFAMYEIYAKQCGAK-- 129 Query: 141 FVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVA 200 + S ++ + +L K + L PNNPLG+ E Sbjct: 130 ----------CYKTQSITHNLDEFKKLYETHKDEIKLIFLCLPNNPLGECLDASEATEFI 179 Query: 201 SLCQQHDVVCITDEVYQWMVY--DGHQHISIASLPGMWERTLTIGSAGKTFSATGWKVGW 258 + D + + D Y D +H+ L ++ L +G+ K + G ++G+ Sbjct: 180 KGVNE-DCLVVIDAAYNEFASFKDSKKHLEPCELIKEFDNVLYLGTFSKLYGLGGLRIGY 238 Query: 259 VLGPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFPQAMQRCRD 318 + +I+ + + F+ + A + + ++ + + F Q + + Sbjct: 239 GIANANIISAFYKLR--APFNVSNLALKAAVAAMDDDEFTEKTLENNFSQMELYKEFAKK 296 Query: 319 HMIRSLQSVGLKPIIPQGSYFLITDISDFKRKMPDLPGAVDEPYDRRFVKWMIKNKGLVA 378 H I+ + S T+ + + ++ + + +K+ GL A Sbjct: 297 HNIKIIDS--------------YTNFITYFFDEKNSTDLSEKLLKKGIIIRNLKSYGLNA 342 Query: 379 IPVSIFYSVPHQKHFDHY 396 I ++I S ++K F + Sbjct: 343 IRITIGTSYENEKFFTEF 360 >1D2F-A nrPDB Length = 390 Score = 155 bits (391), Expect = 3e-38, Method: Composition-based stats. Identities = 65/401 (16%), Positives = 139/401 (34%), Gaps = 45/401 (11%) Query: 18 WVEFVKLASEHDVVNLGQGFPDFPPPDFAVEAF-QHAVSGDFMLNQYTKTFGYPPLTKIL 76 W D++ DF +EA Q + G F +++ + Sbjct: 18 WDYVADRFGTADLLPFTISDMDFATAPCIIEALNQRLMHGVFGYSRWKND----EFLAAI 73 Query: 77 ASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAG 136 A +F ID + V+ + + + G+ V+I P +D + Sbjct: 74 AHWFSTQHYTAID-SQTVVYGPSVIYMVSELIRQWSETGEGVVIHTPAYDAFYKAIEGNQ 132 Query: 137 GRPVFVSLKPGPIQNGELGSSSNWQLDPMELAG-KFTSRTKALVLNTPNNPLGKVFSREE 195 + V+L+ + W D +L K ++L +P NP GKV++ +E Sbjct: 133 RTVMPVALE---------KQADGWFCDMGKLEAVLAKPECKIMLLCSPQNPTGKVWTCDE 183 Query: 196 LELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTIGSAGKTFSATGWK 255 LE++A LC++H V I+DE++ MV+ HI +++ + S K+F+ Sbjct: 184 LEIMADLCERHGVRVISDEIHMDMVWGEQPHIPWSNV--ARGDWALLTSGSKSFNIPALT 241 Query: 256 VGWVLGPDHIMK--HLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFPQAM 313 + + + + +L + P+ + ++Q + + + Sbjct: 242 GAYGIIENSSSRDAYLSALKGRDGLSSPSVL------ALTAHIAAYQQGAPWLDALRIYL 295 Query: 314 QRCRDHMIRSLQS--VGLKPIIPQGSYFLITDISDFKRKMPDLPGAVDEPYDRRFVKWMI 371 + ++ + + L IPQ +Y D+ D K +I Sbjct: 296 KDNLTYIADKMNAAFPELNWQIPQSTYLAWLDLRPLNID------------DNALQKALI 343 Query: 372 KNKGLVAIPVSIFYSVPHQKHFDHYIRFCFVKDEATLQAMD 412 + + + +P + + ++R + L+ Sbjct: 344 EQEKVAIMPG-----YTYGEEGRGFVRLNAGCPRSKLEKGV 379 >3F6T-A nrPDB Length = 533 Score = 153 bits (387), Expect = 1e-37, Method: Composition-based stats. Identities = 77/419 (18%), Positives = 137/419 (32%), Gaps = 74/419 (17%) Query: 56 GDFMLNQYT-KTFGYPPLTKILASFFGELLGQEID--PLRNVLVTVGGYGALFTAFQAL- 111 + N Y KI+ F EL ++ + ++ T GG A+ AF +L Sbjct: 126 NGAVANNYPVPDRCLVNTEKIINYFLQELSYKDANLAEQTDLFPTEGGTAAIVYAFHSLA 185 Query: 112 ----VDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMEL 167 + +GD++ I EP F Y + + V V L ++W+++P E+ Sbjct: 186 ENHLLKKGDKIAINEPIFTPYLRIPELKDYELVEVDLHSY--------EKNDWEIEPNEI 237 Query: 168 AGKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQQH-DVVCITDEVYQWMVYDGHQH 226 KAL++ P NP K F L + +++ ++ I+DEVY V + Sbjct: 238 EKLKDPSIKALIVVNPTNPTSKEFDTNALNAIKQAVEKNPKLMIISDEVYGAFVPNFKSI 297 Query: 227 ISIASLPGMWERTLTIGSAGKTFSATGWKVGWVLGP-----DHIMKHLRTV--------- 272 S+ T+ + S K F TGW++G + D + HL V Sbjct: 298 YSVVPY-----NTMLVYSYSKLFGCTGWRLGVIALNEKNVFDDNIAHLDKVELRQLHKRY 352 Query: 273 --------------------HQNSVFHCPTQS--QAAVAESFEREQLLFRQ----PSSYF 306 ++H S Q + F LL Y Sbjct: 353 SSVVLDPDKMKFIDRLCADSRSIGLYHTAGLSTPQQIMEALFSMTHLLTSTNGGSDDPYI 412 Query: 307 VQFPQAMQRCRDHMIRSLQSVGLKPIIPQGSYFLITDISDFKRKM---PDLPGAVDEPYD 363 + + D + ++Q+ Y+ + DI K+ + Sbjct: 413 DIARKLVSERYDQLHDAMQAPK-DETDTNTHYYSLIDIYRLAEKIYGKEFRDYLTNNFEQ 471 Query: 364 RRFVKWMIKNKGLVAIPVSIFYSVPHQKHFDHYIRFCFVK--DEATLQAMDEKLRKWKV 420 F+ + + G+V + F + P + +R E + L K Sbjct: 472 VDFLLKLAEKNGVVLVDGVGFGAKPGE------LRVSQANLPTEDYALIGKQVLELLKE 524 >6HNB-A nrPDB Length = 491 Score = 147 bits (371), Expect = 9e-36, Method: Composition-based stats. Identities = 79/477 (16%), Positives = 143/477 (29%), Gaps = 94/477 (19%) Query: 16 NPWVEFVKLASEHDVVNLGQGFP------------DFPPPDF--------------AVEA 49 +P K + + LG G P D P P F +E Sbjct: 26 SPLKGIFKYYKQPGITFLGGGLPLSDYFPFEKVTADIPTPSFSGGIGAPIEGENKTTIEV 85 Query: 50 FQHAVSGDFM------LNQYTKTFGYPPLTKILASFFGELLGQEIDPLRNVLVTVGGYGA 103 F+ A QY TFG P + + + + +V+V+VG A Sbjct: 86 FKKAADNVPDQIELARSLQYGSTFGLPEFLQFIKEHTDMVHKVPYE-NWDVIVSVGNTEA 144 Query: 104 LFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLD 163 + + +GD +++ E F G V V++ + + Sbjct: 145 WDSTLRTFCSKGDTILVEEYTFSSALESANGQGVNTVPVTMD-------------EFGII 191 Query: 164 PMELAGKF-----TSRTKALVLNTPNNPLGKVFSREELELVASLCQQHDVVCITDEVYQW 218 P +L + T NP G S E + + + ++D + I DE Y + Sbjct: 192 PEKLEELMSRWVGNKPKFLYTICTGQNPTGSSLSAERRKQIYDIACKYDFLIIEDEPYYF 251 Query: 219 MVYDG-------------HQHISIAS-------LPGMWERTLTIGSAGKTFSATGWKVGW 258 + + H H + R + + S K + G ++GW Sbjct: 252 LQMETYTKDKAAREGKAVHDHDEFLKALVPSFISLDVEGRVVRLDSFSKVLA-PGLRLGW 310 Query: 259 VLGPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFPQAMQRCRD 318 ++G +++ +H+ SV + S A+A + R+ + + RD Sbjct: 311 IVGQKDLLERYVRLHEVSVQNPSGFS-EALANALLRKWGHSGYLD-WLIGLRAEYTHKRD 368 Query: 319 HMIRSLQSVGLKPI----IPQGSYFLITDISDFKRKMPDLPGAVDEPYDRRFV-KWMIKN 373 I +L K + P F ++ K P +++P Sbjct: 369 VAIDALDQFVPKEVSSFNPPVAGMFF--TVTLDASKHPKYKEFLEDPLKVEAAVHEQAIK 426 Query: 374 KGLVAIPVSIFYSVPH------------QKHFDHYIRFCFVK-DEATLQAMDEKLRK 417 +G + P S F + + R + L EK K Sbjct: 427 QGCLLAPGSWFKAEGQSSPPQKNLPANPSHKTHIFFRGTYAAVPLDQLVVGLEKFGK 483 >1UU1-A nrPDB Length = 335 Score = 138 bits (348), Expect = 3e-33, Method: Composition-based stats. Identities = 59/332 (17%), Positives = 108/332 (32%), Gaps = 47/332 (14%) Query: 25 ASEHDVVNLGQGFPDFPPPDFAVEAFQHAVSGDFMLNQYTKTFGYPPLTKILASFFGELL 84 + D L FP P+ V+ ++ D + Y + L L Sbjct: 16 TEKRDKTYLALNENPFPFPEDLVDEVFRRLNSDALRIYYDSPD------EELIEKILSYL 69 Query: 85 GQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVSL 144 + NV V G ++ D + P + CY G + + V L Sbjct: 70 DTDFLSKNNVSVGNGADEIIYVMMLMF----DRSVFFPPTYSCYRIFAKAVGAKFLEVPL 125 Query: 145 KPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQ 204 + + + PNNP G VF REE+E + Sbjct: 126 TKDLRIPEVNVGEGD-----------------VVFIPNPNNPTGHVFEREEIERIL---- 164 Query: 205 QHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTIGSAGKTFSATGWKVGWVLGPDH 264 + DE Y Y+ H S +E I + K FS +VG+V+ + Sbjct: 165 KTGAFVALDEAY----YEFHGE-SYVDFLKKYENLAVIRTFSKAFSLAAQRVGYVVASEK 219 Query: 265 IMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFPQAMQRCRDHMIRSL 324 + V F+ SQ + + ++ F + + + R+ M +L Sbjct: 220 FIDAYNRVR--LPFNVSYVSQMFAKVALDHREI--------FEERTKFIVEERERMKSAL 269 Query: 325 QSVGLKPIIPQGSY-FLITDISDFKRKMPDLP 355 + +G + +G++ F+ + + +R + L Sbjct: 270 REMGYRITDSRGNFVFVFMEKEEKERLLEHLR 301 >3CQ5-A nrPDB Length = 369 Score = 134 bits (336), Expect = 9e-32, Method: Composition-based stats. Identities = 52/347 (14%), Positives = 104/347 (29%), Gaps = 30/347 (8%) Query: 31 VNLGQGFPDFPPPDFAVEAFQHAVSGDFMLNQYTKTFGYPPLTKILASFFGELLGQEIDP 90 + L +PP + V V L LA++ + G + Sbjct: 33 IRLNTNENPYPPSEALVADLVATVDKIATELNRYPERDAVELRDELAAYITKQTGVAVT- 91 Query: 91 LRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPIQ 150 N+ G L QA G + +P + + + + VS Sbjct: 92 RDNLWAANGSNEILQQLLQAFGGPGRTALGFQPSYSMHPILAKGTHTEFIAVS------- 144 Query: 151 NGELGSSSNWQLDPM-ELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQQHDVV 209 +++++D L + + + TPNNP G V S +++E + ++ + Sbjct: 145 -----RGADFRIDMDVALEEIRAKQPDIVFVTTPNNPTGDVTSLDDVERIINVAPG---I 196 Query: 210 CITDEVYQWMVYDGHQHISIASLPGMWERTLTIGSAGKTFSATGWKVGWVLGPDHIMKHL 269 I DE Y + P + + + K F G ++G+ + + + Sbjct: 197 VIVDEAYAEFSPSPSATTLLEKYPT---KLVVSRTMSKAFDFAGGRLGYFVANPAFIDAV 253 Query: 270 RTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFPQAMQRCRDHMIRSLQSVGL 329 V +H SQAA + + + R + L+ +G Sbjct: 254 MLVR--LPYHLSALSQAAAIVALRHSADTLGT--------VEKLSVERVRVAARLEELGY 303 Query: 330 KPIIPQGSYFLITDISDFKRKMPDLPGAVDEPYDRRFVKWMIKNKGL 376 + + ++ D SD D + G+ Sbjct: 304 AVVPSESNFVFFGDFSDQHAAWQAFLDRGVLIRDVGIAGHLRTTIGV 350 >4JE5-A nrPDB Length = 503 Score = 131 bits (328), Expect = 7e-31, Method: Composition-based stats. Identities = 78/460 (16%), Positives = 144/460 (31%), Gaps = 92/460 (20%) Query: 2 AKQLQARRLDGIDYNPWVEFVKLASEHDVVNLGQGFP------------DFPPPDFAV-- 47 + + AR+ +P + L + +++ LG G P D P P F Sbjct: 17 SDETNARK-----PSPLKTCIHLFQDPNIIFLGGGLPLKDYFPWDNLSVDSPKPPFPQGI 71 Query: 48 -------EAFQHAVSGDFM--------------LNQYTKTFGYPPLTKILASFFGELLGQ 86 ++ V+ D+ QY + G P L + + Sbjct: 72 GAPIDEQNCIKYTVNKDYADKSANPSNDIPLSRALQYGFSAGQPELLNFIRDHTKIIHDL 131 Query: 87 EIDPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVSLKP 146 + +VL T G A + + + GD +++ F G V + Sbjct: 132 KYK-DWDVLATAGNTNAWESTLRVFCNRGDVILVEAHSFSSSLASAEAQGVITFPVPIDA 190 Query: 147 -GPIQNGELGSSSNWQLDPMELAGKFTSRTKALV-LNTPNNPLGKVFSREELELVASLCQ 204 G I NW + K L + T NP G + E + + Q Sbjct: 191 DGIIPEKLAKVMENWTPGA--------PKPKLLYTIPTGQNPTGTSIADHRKEAIYKIAQ 242 Query: 205 QHDVVCITDEVYQWMVYDG----------------HQHISIAS-------LPGMWERTLT 241 ++D + + DE Y ++ + H R + Sbjct: 243 KYDFLIVEDEPYYFLQMNPYIKDLKEREKAQSSPKQDHDEFLKSLANTFLSLDTEGRVIR 302 Query: 242 IGSAGKTFSATGWKVGWVLGPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQ 301 + S K + G ++GW+ G I+K ++H+ ++ +Q V + R + Sbjct: 303 MDSFSKVLA-PGTRLGWITGSSKILKPYLSLHEMTIQAPAGFTQVLVNATLSRWG--QKG 359 Query: 302 PSSYFVQFPQAMQRCRDHMIRSL-----QSVGLKPIIPQGSYFLITDI-----SDFKRKM 351 + + RD I +L QS P F +I +FK K Sbjct: 360 YLDWLLGLRHEYTLKRDCAIDALYKYLPQSDAFVINPPIAGMFFTVNIDASVHPEFKTKY 419 Query: 352 PDLPGAVDEPYDRRFVKWMIKNKGLVAIPVSIFYSVPHQK 391 P +++ + V+ G++ +P S F S + Sbjct: 420 NSDPYQLEQSLYHKVVER-----GVLVVPGSWFKSEGETE 454 >4RAE-A nrPDB Length = 394 Score = 124 bits (310), Expect = 8e-29, Method: Composition-based stats. Identities = 52/342 (15%), Positives = 109/342 (31%), Gaps = 31/342 (9%) Query: 37 FPDFPPPDFAVEAFQHAVSGDFMLNQYTKTFGYPPLTKILASFFGELLGQEIDPLRNVLV 96 P P + + L++Y L LA + G ++ + N+ Sbjct: 42 NPHPPTRALVDDVVRSVREAAIDLHRY-PDRDAVALRADLAGYLTAQTGIQLG-VENIWA 99 Query: 97 TVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGS 156 G L QA G I P + + + E Sbjct: 100 ANGSNEILQQLLQAFGGPGRSAIGFVPSYS------------MHPIISDGTHTEWIEASR 147 Query: 157 SSNWQLDPMELAGKFTSRT-KALVLNTPNNPLGKVFSREELELVASLCQQHDVVCITDEV 215 ++++ LD R + + +PNNP G+ S +L + + + I DE Sbjct: 148 ANDFGLDVDVAVAAVVDRKPDVVFIASPNNPSGQSVSLPDLCKLLDVAPG---IAIVDEA 204 Query: 216 YQWMVYDGHQHISIASLPGMWERTLTIGSAGKTFSATGWKVGWVLGPDHIMKHLRTVHQN 275 Y Q +++ + + + + K F+ G ++G+++ ++ + V Sbjct: 205 YGEF---SSQPSAVSLVEEYPSKLVVTRTMSKAFAFAGGRLGYLIATPAVIDAMLLVR-- 259 Query: 276 SVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFPQAMQRCRDHMIRSLQSVGLKPIIPQ 335 +H + +QAA + ++ + R+ + SL +G + I Sbjct: 260 LPYHLSSVTQAAARAALRHSDDTLSSVAALIAE--------RERVTTSLNDMGFRVIPSD 311 Query: 336 GSYFLITDISDFKRKMPDLPGAVDEPYDRRFVKWMIKNKGLV 377 ++ L + +D A D ++ GL Sbjct: 312 ANFVLFGEFADAPAAWRRYLEAGILIRDVGIPGYLRATTGLA 353 >3FFH-A nrPDB Length = 363 Score = 122 bits (306), Expect = 3e-28, Method: Composition-based stats. Identities = 45/271 (16%), Positives = 88/271 (32%), Gaps = 31/271 (11%) Query: 71 PLTKILASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEP 130 L K +A F+ ++ T G + + L+D ++ P F Y Sbjct: 71 SLRKEVADFYQ-------LEEEELIFTAGVDELIELLTRVLLDTTTNTVMATPTFVQYRQ 123 Query: 131 MTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKV 190 ++ G + L D + +T + + PNNP G Sbjct: 124 NALIEGAEVREIPLLQDGEH------------DLEGMLNAIDEKTTIVWICNPNNPTGNY 171 Query: 191 FSREELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTIGSAGKTFS 250 +++ DV+ + DE Y V Q L ++ + + K + Sbjct: 172 IELADIQAFLDRVP-SDVLVVLDEAYIEYV--TPQPEKHEKLVRTYKNLIITRTFSKIYG 228 Query: 251 ATGWKVGWVLGPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFP 310 +VG+ + I++ L V F+ + Q E+ + + + +S Sbjct: 229 LASARVGYGIADKEIIRQLNIVRPP--FNTTSIGQKLAIEAIKDQAFIGECRTSNANGIK 286 Query: 311 QAMQRCRDHMIRSLQSVGLKPIIPQGSYFLI 341 Q + + + V L P G++ LI Sbjct: 287 QY-----EAFAKRFEKVKLYP--ANGNFVLI 310 >3EUC-A nrPDB Length = 367 Score = 122 bits (305), Expect = 4e-28, Method: Composition-based stats. Identities = 60/330 (18%), Positives = 112/330 (33%), Gaps = 39/330 (11%) Query: 28 HDVVNLGQGFPDFPPPDFAVEAFQHAVSGDFMLNQYTKTFGYPPLTKILASFFGELLGQE 87 H +V L + P + G+ LN+Y P ++ L + E++ + Sbjct: 30 HGLVKLDAMENPYRLPPALRSELAARL-GEVALNRYPV-----PSSEALRAKLKEVM--Q 81 Query: 88 IDPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPG 147 + VL+ G + A G +V+ P F Y AG V V L+ Sbjct: 82 VPAGMEVLLGNGSDEIISMLALAAARPGAKVMAPVPGFVMYAMSAQFAGLEFVGVPLR-- 139 Query: 148 PIQNGELGSSSNWQLDPMELAGKFTSR-TKALVLNTPNNPLGKVFSREELELVASLCQQH 206 +++ LD + + L PNNP G +F ++E + Q Sbjct: 140 ----------ADFTLDRGAMLAAMAEHQPAIVYLAYPNNPTGNLFDAADMEAIVRAAQGS 189 Query: 207 --DVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTIGSAGKTFSATGWKVGWVLGPDH 264 + + DE YQ S S + L + + K G ++G+V G Sbjct: 190 VCRSLVVVDEAYQPFA-----QESWMSRLTDFGNLLVMRTVSK-LGLAGIRLGYVAGDPQ 243 Query: 265 IMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFPQAMQRCRDHMIRSL 324 ++ L V + T++ A A + + + ++ R + + Sbjct: 244 WLEQLDKVRPPYNVNVLTEATALFAL----------EHVAVLDEQAAQLRAERSRVAEGM 293 Query: 325 QSVGLKPIIPQGSYFLITDISDFKRKMPDL 354 + G + P + FL+ + D + L Sbjct: 294 AAHGGVTVFPSAANFLLARVPDAAQTFDRL 323 >3FTB-A nrPDB Length = 361 Score = 115 bits (288), Expect = 3e-26, Method: Composition-based stats. Identities = 46/300 (15%), Positives = 102/300 (34%), Gaps = 37/300 (12%) Query: 43 PDFAVEAFQHAVSGDFMLNQYTKTFGYPPLTKILASFFGELLGQEIDPLRNVLVTVGGYG 102 P ++F + + Y L K + ++ +++ G Sbjct: 37 PLGIPKSFLNNIDEGIKNLGVYPDVNYRRLNKSIENYLK-------LKDIGIVLGNGASE 89 Query: 103 ALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQL 162 + + ++++II P + YE G VF L N + Sbjct: 90 IIELSISLF----EKILIIVPSYAEYEINAKKHGVSVVFSYLD------------ENMCI 133 Query: 163 DPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQQHDVVCITDEVYQWMVYD 222 D ++ K ++++ PNNP G + ++E+ V L ++ I DE + + + Sbjct: 134 DYEDIISKIDD-VDSVIIGNPNNPNGGLINKEKFIHVLKLAEEKKKTIIIDEAF--IEFT 190 Query: 223 GHQHISIASLPGMWERTLTIGSAGKTFSATGWKVGWVLGPDHIMKHLRTVHQNSVFHCPT 282 G S + I + K F+ G + G+ + + + QN ++ Sbjct: 191 GDPSSSFVGEIKNYSCLFIIRAMTKFFAMPGIRFGYGITNNKEIAAKIKAKQN-PWNINC 249 Query: 283 QSQAAVAESFEREQLLFRQPSSYFVQFPQAMQRCRDHMIRSLQSVGL--KPIIPQGSYFL 340 ++ A + ++Y + +++ R I L +G + P ++ L Sbjct: 250 FAEMAAINCLKD--------TNYIEESLLWIKKERKRFIEELNKIGFIKRVFSPHANFVL 301 >5DJ3-A nrPDB Length = 376 Score = 112 bits (281), Expect = 2e-25, Method: Composition-based stats. Identities = 61/341 (17%), Positives = 112/341 (32%), Gaps = 41/341 (12%) Query: 83 LLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPVFV 142 G +P R VL ++ ++L D V ++ P FD + G V V Sbjct: 74 QHGYPAEPGR-VLSCYSSSVSMEILARSLSASVDRVALVHPTFDNIADLLRGNGLDLVPV 132 Query: 143 SLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASL 202 L +L+ + S + + TPNNP G+V + E L +A Sbjct: 133 EEDA---------------LHGADLSAELLSSVGCVFVTTPNNPTGRVLAEERLRRLAEQ 177 Query: 203 CQQHDVVCITDEVYQWMVYDGH-QHISIASLPGMWERTLTIGSAGKTFSATGWKVGWVLG 261 C +H V D ++ H H ++ G R + I GK + K G ++ Sbjct: 178 CAEHGTVLALDTSFRGFDAAAHYDHYAVLQEAGC--RWVVIEDTGKLWPTLDLKAGLLVF 235 Query: 262 PDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFPQAMQRCRDHMI 321 + I + ++ + + + A+ F R+ + R + Sbjct: 236 SEDIGLPVEKIYSDILLGV-SPLILALIREFSRDA-----ADGGLADLHAFILHNRSVVR 289 Query: 322 RSLQSV-GLKPIIPQGSYFLITDISDFKRKMPDLPGAVDEPYDRRFVKWMIKNKGLVAIP 380 R+L V G+ P+ S +R + + ++ + A+P Sbjct: 290 RALAGVEGVSFPDPE-------SRSSVERVAFAGRTGTEVWEE-------LQRHHVFALP 335 Query: 381 VSIFYSVPHQKHFDHYIRFCFVKDEATLQAMDEKLRKWKVE 421 F+ DH +R + L+ + LR Sbjct: 336 CRQFH-WAEPSDGDHMVRIALSRSTEPLEKSVQVLRTVLET 375 >3LY1-A nrPDB Length = 354 Score = 111 bits (277), Expect = 7e-25, Method: Composition-based stats. Identities = 49/329 (14%), Positives = 109/329 (33%), Gaps = 53/329 (16%) Query: 94 VLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGE 153 +L+T G + A +A +++I E + E +AG + V Sbjct: 71 ILLTAGSSEGIRAAIEAYASLEAQLVIPELTYGDGEHFAKIAGMKVTKV----------- 119 Query: 154 LGSSSNWQLDPMELAGKFT--SRTKALVLNTPNNPLGKVFSREELELVASLCQQH-DVVC 210 NW D L S + L PNNP G + + +E + + + + Sbjct: 120 -KMLDNWAFDIEGLKAAVAAYSGPSIVYLVNPNNPTGTITPADVIEPW--IASKPANTMF 176 Query: 211 ITDEVYQWMVYDGHQHISIASLPGMWERTLTIGSAGKTFSATGWKVGWVLGPDHIMKHLR 270 I DE Y V D + E + + + K + G +VG+ + ++ + Sbjct: 177 IVDEAYAEFVNDPRFRSISPMITQGAENIILLKTFSKIHAMAGMRVGYAVAHPTVIALMG 236 Query: 271 TVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFPQAMQRCRDHMIRSLQSVGLK 330 + AA+A S++ ++ R ++++L+ + L Sbjct: 237 RYVAGEKINFSGV-DAALASM---------NDSAFITYSKKSNDVSRQILLKALEDLKLP 286 Query: 331 PIIPQGSYFLITDISDFKRKMPDLPGAVDEPYDRRFVKWMIKNKGLVAIPVSIFYSVPHQ 390 + +G++ + K + + G++ F Sbjct: 287 YLPSEGNFVFHQLVVPLKDYQTH-----------------MADAGVLI--GRAFPP---- 323 Query: 391 KHFDHYIRFCFVKDEATLQAMDEKLRKWK 419 D++ R + +Q + + +R+++ Sbjct: 324 --ADNWCRISLGTPQE-MQWVADTMREFR 349 >3P1T-A nrPDB Length = 337 Score = 107 bits (268), Expect = 7e-24, Method: Composition-based stats. Identities = 48/318 (15%), Positives = 101/318 (31%), Gaps = 61/318 (19%) Query: 90 PLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPI 149 P N+++ G + P FD Y ++G R + L + Sbjct: 67 PEDNLMLVRGIDECFDRISAEFSSM--RFVTAWPGFDGYRARIAVSGLRHFEIGLTDDLL 124 Query: 150 QNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQQHDVV 209 + + SR +VL P+NP G+ S EL+ + + Sbjct: 125 LDPNDLAQV--------------SRDDCVVLANPSNPTGQALSAGELDQLRQRAGK---- 166 Query: 210 CITDEVYQWMVYDGHQHISIASLPGMWERTLTIGSAGKTFSATGWKVGWVLGPDHIMKHL 269 + DE Y Y + +A E L S K++ G ++G + GP ++ + Sbjct: 167 LLIDETYVD--YSSFRARGLA----YGENELVFRSFSKSYGLAGLRLGALFGPSELIAAM 220 Query: 270 RTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFPQAMQRCRDHMIRSLQSVGL 329 + Q + T A+ + + ++ + Q R + +L+ +G Sbjct: 221 KR-KQWFC-NVGTLDLHALEAALDNDRAREAHIAKTLAQ--------RRRVADALRGLGY 270 Query: 330 KPIIPQGSYFLITDISDFKRKMPDLPGAVDEPYDRRFVKWMIKNKGLVAIPVSIFYSVPH 389 + + ++ L+ + + ++ +G+ F Sbjct: 271 RVASSEANFVLVENAAG------------------ERTLRFLRERGIQVKDAGQFGL--- 309 Query: 390 QKHFDHYIRFCFVKDEAT 407 H+IR ++E Sbjct: 310 ----HHHIRISIGREEDN 323 >4WBT-A nrPDB Length = 376 Score = 106 bits (265), Expect = 2e-23, Method: Composition-based stats. Identities = 69/417 (16%), Positives = 124/417 (29%), Gaps = 70/417 (16%) Query: 15 YNPWV--EFVKLASEHDVV-NLGQGFPDFPPPDFAVEAFQHAVSGDFMLNQYTKTFGYPP 71 P+V E ++ + +G F P + A + A + +Y + Sbjct: 20 SVPFVGPEALERQHGRKIAARIGANESGFGPAPSVLLAIRQAAGDTW---KYADPENHD- 75 Query: 72 LTKILASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPM 131 L + LA G N+ + G G L + +V+ G V+ + + Sbjct: 76 LKQALARHLG-------TSPANIAIGEGIDGLLGQIVRLVVEAGAPVVTSLGGYPTFNYH 128 Query: 132 TMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTK----ALVLNTPNNPL 187 GGR V V + D +L G + + + L P+NP+ Sbjct: 129 VAGHGGRLVTVP----------------YADDREDLEGLLAAVGRENAPLVYLANPDNPM 172 Query: 188 GKVFSREELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTIGSAGK 247 G + E + A + + + DE Y I SL + + K Sbjct: 173 GSWWPAERVVAFAQALPET-TLLVLDEAYCETAPRDALP-PIESLID-KPNVIRARTFSK 229 Query: 248 TFSATGWKVGWVLGPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYFV 307 + G ++G+ L + + + + + Y Sbjct: 230 AYGLAGARIGYTLSTPGTAQAFDKIRNHFGMSRIGVA----------AAIAALADQDYLK 279 Query: 308 QFPQAMQRCRDHMIRSLQSVGLKPIIPQGSYFLITDISDFKRKMPDLPGAVDEPYDRRFV 367 + + R + R GL P+ P + F+ D D Y R V Sbjct: 280 EVTLKIANSRQRIGRIAADSGLAPL-PSATNFVAVDC------------GKDASYARAIV 326 Query: 368 KWMIKNKGLVAIPVSIFYSVPHQKHFDHYIRFCFVKD-EATLQAMD--EKLRKWKVE 421 ++ + G+ F +P + IR D E L A E +R Sbjct: 327 DRLMSDHGI-------FIRMPGVAPLNRCIRISTAPDAEMDLLAAALPEVIRSLAAT 376 >4N0B-A nrPDB Length = 479 Score = 106 bits (265), Expect = 2e-23, Method: Composition-based stats. Identities = 46/318 (14%), Positives = 108/318 (33%), Gaps = 39/318 (12%) Query: 12 GIDYNPWVEFVKLASEHDVVNLGQGFPDFPPPDFAVEAFQHAVSGDFMLNQYTKTFGYPP 71 ID + W+ F ++S+ D FP + + A L + G Sbjct: 103 HIDQSDWISFSHMSSDTD---------HFPIKSWFRCEQKAASRSYRTLGDMSHPQGIYE 153 Query: 72 LTKILASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPM 131 + + G + P + ++ G L L+ + + EP + + Sbjct: 154 VRAAITRLISLTRGVKCRPEQMIIGA--GTQVLMQLLTELLPKEAVYAMEEPGYRRMYQL 211 Query: 132 TMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNN--PLGK 189 AG + + L + E+ Q D +++ TP++ P G Sbjct: 212 LKNAGKQVKTIMLDEKGMSIAEITRQ---QPD--------------VLVTTPSHQFPSGT 254 Query: 190 VFSREELELVASLCQQH-DVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTIGSAGKT 248 + + + + I D+ YD ++ SL ++ + +G+ K+ Sbjct: 255 IMPVSRRIQLLNWAAEEPRRYIIEDDYDSEFTYDVDSIPALQSLDR-FQNVIYMGTFSKS 313 Query: 249 FSATGWKVGWVLGPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQ 308 G ++ +++ P +++ + C + +Q + E E + + + Sbjct: 314 L-LPGLRISYMVLPPELLRAY-KQRGYDLQTCSSLTQLTLQEFIESGEY-----QKHIKK 366 Query: 309 FPQAMQRCRDHMIRSLQS 326 Q + R+ +I +L++ Sbjct: 367 MKQHYKEKRERLITALEA 384 >3FKD-A nrPDB Length = 350 Score = 106 bits (264), Expect = 2e-23, Method: Composition-based stats. Identities = 48/321 (14%), Positives = 97/321 (30%), Gaps = 51/321 (15%) Query: 26 SEHDVVNLGQGFPDFPPPDFAVEAFQHAVSGDFMLN-----QYT-KTFGYPPLTKILASF 79 + + L +F + + + + N Y G L ++LA Sbjct: 6 GDEGITPLSSEIVNFST-TVWTDGDKDHLEKHLVENLNCIRHYPEPDAGT--LRQMLAKR 62 Query: 80 FGELLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRP 139 +D +LVT G A + QA G +I P F YE M Sbjct: 63 ------NSVD-NNAILVTNGPTAAFYQIAQAF--RGSRSLIAIPSFAEYEDACRMYEHEV 113 Query: 140 VFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELV 199 F + W L PNNP G++ R E+ + Sbjct: 114 CFYPSNEDIGEADFSNMDFCW-------------------LCNPNNPDGRLLQRTEILRL 154 Query: 200 ASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTIGSAGKTFSATGWKVGWV 259 + D + D+ Y + + + + + + S + G ++G++ Sbjct: 155 LN--DHPDTTFVLDQSYVSFT---TEEVIRPADIKGRKNLVMVYSFSHAYGIPGLRIGYI 209 Query: 260 LGPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFPQAMQRCRDH 319 + MK + + A + E + + P+ + + + + D Sbjct: 210 VANKDFMKRVAAFSTPWAVN---------ALAIEAAKFILIHPAQFTLPIRKWQRNTVDF 260 Query: 320 MIRSLQSVGLKPIIPQGSYFL 340 + + G++ ++FL Sbjct: 261 ITALNRLDGVEVHPSGTTFFL 281 >1LC8-A nrPDB Length = 364 Score = 103 bits (256), Expect = 2e-22, Method: Composition-based stats. Identities = 52/323 (16%), Positives = 100/323 (30%), Gaps = 36/323 (11%) Query: 29 DVVNLGQGFPDFPPPDFAVEAFQHAVSGDFMLNQYTKTFGYPPLTKILASFFGELLGQEI 88 +++ P A + + +Y Y L + LA Sbjct: 25 QLLDFSANINPLGMPVSVKRALIDNLD---CIERYPDAD-YFHLHQALARHHQ------- 73 Query: 89 DPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPGP 148 P +L G ++FT L +I+ P F Y +G SL+ Sbjct: 74 VPASWILAGNGETESIFTVASGLKPR--RAMIVTPGFAEYGRALAQSGCEIRRWSLR--- 128 Query: 149 IQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQQHDV 208 + WQL L T L L TPNNP G + R L+ +A C+ ++ Sbjct: 129 -------EADGWQLTDAILEAL-TPDLDCLFLCTPNNPTGLLPERPLLQAIADRCKSLNI 180 Query: 209 VCITDEVYQWMVYDGHQHISIASLPGMWERTLTIGSAGKTFSATGWKVGWVLGPDHIMKH 268 I DE + + I + S K ++ G ++G+++ D Sbjct: 181 NLILDEAFIDFIPHETGFIPAL---KDNPHIWVLRSLTKFYAIPGLRLGYLVNSDD--AA 235 Query: 269 LRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFPQAMQRCRDHMIRSLQSVG 328 + + + + A E ++ + + + ++L + Sbjct: 236 MARMRRQQMPWSVNALAALAGEVALQDSAWQQATWHWL-------REEGARFYQALCQLP 288 Query: 329 LKPIIPQGSYFLITDISDFKRKM 351 L + P + +L+ + Sbjct: 289 LLTVYPGRANYLLLRCEREDIDL 311 >3RQ1-A nrPDB Length = 418 Score = 102 bits (253), Expect = 4e-22, Method: Composition-based stats. Identities = 60/310 (19%), Positives = 114/310 (36%), Gaps = 42/310 (13%) Query: 56 GDFMLNQYTKTFGYPPLTKILASFFGELLGQEIDPLRNV--LVTVGGYGALFTAFQALVD 113 D Y G P L + E G P ++ + T GG G + + Sbjct: 69 SDSEHVGYAPIAGIPDF---LCAAEKECFGN-FRPEGHIRSIATAGGTGGIHHLIHNYTE 124 Query: 114 EGDEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTS 173 GDEV+ + ++ Y + G V SL + +Q ELA K T+ Sbjct: 125 PGDEVLTADWYWGAYRVICSDTGRTLVTYSL----FDEHNNFNHEAFQNRVNELAAKQTN 180 Query: 174 RTKALVLNTP-NNPLGKVFSREELELVASLCQ------QHDVVCITDEVYQWMVYDGHQ- 225 ++ NTP NNP G ++ + + + + +++V+ D Y + Y G + Sbjct: 181 VV--VIFNTPGNNPTGYSIEDKDWDSILNFLKDLVAIGRNNVIIGIDVAY--LDYSGEKD 236 Query: 226 -----HISIASLPGMWERTLTIGSAGKTFSATGWKVGWVLG---PDHIMKHLRTVHQ--- 274 + LP T S K F+ G +VG ++G + I V++ Sbjct: 237 EVRAFFNKFSHLPKEI-LTCVCYSLSKGFTMYGQRVGAMIGISDDEEIADEFFEVNKSTS 295 Query: 275 ----NSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFPQAMQRCRDHMIRSLQSVGLK 330 +++ ++ A + + + + + Y+ Q ++ D + VGL Sbjct: 296 RATWSNICRPAMRTMANIVADPAKFKEYEAERNCYY----QLIRDRADIFKQEAAQVGLP 351 Query: 331 PIIPQGSYFL 340 + +G +F+ Sbjct: 352 MLPYRGGFFI 361 >5X03-B nrPDB Length = 365 Score = 101 bits (252), Expect = 4e-22, Method: Composition-based stats. Identities = 36/266 (13%), Positives = 91/266 (34%), Gaps = 30/266 (11%) Query: 64 TKTFGYPPLTKILASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEP 123 + G + + G + P + ++ G L L+ + + EP Sbjct: 39 SHPQGIYEVRAAITRLISLTRGVKCRPEQMIIGA--GTQVLMQLLTELLPKEAVYAMEEP 96 Query: 124 FFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTP 183 + + AG + + L + E+ Q D +++ TP Sbjct: 97 GYRRMYQLLKNAGKQVKTIMLDEKGMSIAEITRQ---QPD--------------VLVTTP 139 Query: 184 NN--PLGKVFSREELELVASLCQQH-DVVCITDEVYQWMVYDGHQHISIASLPGMWERTL 240 ++ P G + + + + I D+ YD ++ SL ++ + Sbjct: 140 SHQFPSGTIMPVSRRIQLLNWAAEEPRRYIIEDDYDSEFTYDVDSIPALQSLDR-FQNVI 198 Query: 241 TIGSAGKTFSATGWKVGWVLGPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFR 300 +G+ K+ G ++ +++ P +++ + C + +Q + E E + Sbjct: 199 YMGTFSKSL-LPGLRISYMVLPPELLRAY-KQRGYDLQTCSSLTQLTLQEFIESGEY--- 253 Query: 301 QPSSYFVQFPQAMQRCRDHMIRSLQS 326 + + Q + R+ +I +L++ Sbjct: 254 --QKHIKKMKQHYKEKRERLITALEA 277 >2X5F-A nrPDB Length = 430 Score = 100 bits (249), Expect = 1e-21, Method: Composition-based stats. Identities = 45/306 (14%), Positives = 109/306 (35%), Gaps = 24/306 (7%) Query: 63 YTKTFGYPPLTKILASFFGELLG-QEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVIII 121 Y G L + ID + +VT L V++ D +++ Sbjct: 84 YAPPQGIEELRDLWQQKMLRDNPELSIDNMSRPIVTNALTHGLSLVGDLFVNQDDTILLP 143 Query: 122 EPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLN 181 E + Y+ + G +L+ PI + + +++ + L + ++LN Sbjct: 144 EHNWGNYKLVFNTRNG----ANLQTYPIFDKDGHYTTDSLV--EALQSYNKDKV-IMILN 196 Query: 182 TPNNPLGKVFSREELELVASLC-----QQHDVVCITDEVYQWMVYDGHQHISIAS-LPGM 235 PNNP G + +E+ + + V+ + D+ Y + Y+ S+ + L + Sbjct: 197 YPNNPTGYTPTHKEVTTIVEAIKALANKGTKVIAVVDDAYYGLFYEDVYTQSLFTALTNL 256 Query: 236 WERTLT---IGSAGKTFSATGWKVGWVLG------PDHIMKHLRT-VHQNSVFHCPTQSQ 285 + + A K F A G++VG++ +++ + ++++ P +Q Sbjct: 257 HSNAILPIRLDGATKEFFAWGFRVGFMTFGTSDQTTKEVLEAKVKGLIRSNISSGPLPTQ 316 Query: 286 AAVAESFEREQLLFRQPSSYFVQFPQAMQRCRDHMIRSLQSVGLKPIIPQGSYFLITDIS 345 +AV + + ++ + + ++ + + YF+ + Sbjct: 317 SAVKHVLKNNKQFDKEIEQNIQTLKERYEVTKEVVYADQYHSHWQAYDFNSGYFMAIKVH 376 Query: 346 DFKRKM 351 D + Sbjct: 377 DVDPEA 382 >3FSL-A nrPDB Length = 397 Score = 94.9 bits (234), Expect = 7e-20, Method: Composition-based stats. Identities = 66/401 (16%), Positives = 120/401 (29%), Gaps = 35/401 (8%) Query: 10 LDGIDYNPWVEFVKLASEHDVVNLGQG-----FPDFPPPDFAVEAFQHAVSGDFMLNQYT 64 G +E K D VNL G P EA + + Y Sbjct: 8 YAGDPILTLMERFKEDPRSDKVNLSIGLYYNEDGIIPQLQAVAEAEARLNAQPHGASLYL 67 Query: 65 KTFGYPPLTKILASFFGELLGQEIDPLRNVLV-TVGGYGALFTAFQALVD---EGDEVII 120 G +A + R + T+GG GAL + V + Sbjct: 68 PMEGLNCYRHAIAPLLFGADHPVLKQQRVATIQTLGGSGAL-KVGADFLKRYFPESGVWV 126 Query: 121 IEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVL 180 +P ++ + + AG VS P + ++ LA T + ++VL Sbjct: 127 SDPTWENHVAIFAGAG---FEVSTYPWYDEATNGVRFNDL------LATLKTLQAGSIVL 177 Query: 181 NTP--NNPLGKVFSREELELVASLCQQHDVVCITDEVYQWMVYD-GHQHISIASLPGMWE 237 P +NP G + ++ + V + + +++ D YQ +I ++ Sbjct: 178 LHPCCHNPTGADLTNDQWDAVIEILKARELIPFLDIAYQGFGAGMEEDAYAIRAIASAGL 237 Query: 238 RTLTIGSAGKTFSATGWKV-GWVLGPDH------IMKHLRTVHQNSVFHCPTQSQAAVAE 290 L S K FS G +V G + + ++ L+ + + P VA Sbjct: 238 PALVSNSFSKIFSLYGERVGGLSVMCEDAEAAGRVLGQLKATVRRNYSSPPNFGAQVVAA 297 Query: 291 SFEREQLLFRQPSSYFVQFPQAMQRCRDHMIRSLQ----SVGLKPIIPQGSYFLITDISD 346 E L + + R +++ L ++ Q F T +S Sbjct: 298 VLNDEA-LKASWLKEVEEMRTRILAMRQELVKVLSTEMPERNFDYLLNQRGMFSYTGLSA 356 Query: 347 FKRKMPDLPGAVDEPYDRRFVKWMIKNKGLVAIPVSIFYSV 387 + V R + + + F +V Sbjct: 357 AQVDRLREEFGVYLIASGRMCVAGLNTANVQRV-AKAFAAV 396 >4F5M-A nrPDB Length = 406 Score = 91.4 bits (225), Expect = 7e-19, Method: Composition-based stats. Identities = 69/402 (17%), Positives = 114/402 (28%), Gaps = 61/402 (15%) Query: 8 RRLDGIDYNPWVEFVKLA------SEHDVVNLGQG---FPDFPPP--DFAVEAFQHAVSG 56 + I P + LA +NLG G P +A Q+ + Sbjct: 10 GTFENITAAPADPILGLADLFRADERPGKINLGIGVYKDETGKTPVLTSVKKAEQYLLEN 69 Query: 57 DFMLNQYTKTFGYPPL-TKILASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQALVDEG 115 + N Y G P FG+ D T GG GAL A L Sbjct: 70 ETTKN-YLGIDGIPEFGRCTQELLFGKGSALINDKRARTAQTPGGTGALRVAADFLAKNT 128 Query: 116 D--EVIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTS 173 V + P + ++ + AG + + N LD L Sbjct: 129 SVKRVWVSNPSWPNHKSVFNSAGLEVREYA----------YYDAENHTLDFDALINSLNE 178 Query: 174 RTKALVL-----NTPNNPLGKVFSREELELVASLCQQHDVVCITDEVYQWMVYD-GHQHI 227 V+ +NP G + E+ + +A L + + + D YQ Sbjct: 179 AQAGDVVLFHGCC--HNPTGIDPTLEQWQTLAQLSVEKGWLPLFDFAYQGFARGLEEDAE 236 Query: 228 SIASLPGMWERTLTIGSAGKTFSATGWKVG---WVLGPDHIMKHL---RTVHQNSVFHCP 281 + + M + + S K F +VG V + + + P Sbjct: 237 GLRAFAAMHKELIVASSYSKNFGLYNERVGACTLVAADSETVDRAFSQMKAAIRANYSNP 296 Query: 282 TQSQAAVAESFEREQLLFRQPSSYFVQFPQAMQRCRDHMIRSLQSVG----LKPIIPQGS 337 A+V + L Q +QR R + +LQ G II Q Sbjct: 297 PAHGASVVATILSNDALRAIWEQELTDMRQRIQRMRQLFVNTLQEKGANRDFSFIIKQNG 356 Query: 338 YFLITDISDFKRKMPDLPGAVDEPYDRRFVKWMIKNKGLVAI 379 F + ++ + V + + G+ A+ Sbjct: 357 MFSFSGLT------------------KEQVLRLREEFGVYAV 380 >4EMY-A nrPDB Length = 413 Score = 89.9 bits (221), Expect = 2e-18, Method: Composition-based stats. Identities = 54/316 (17%), Positives = 96/316 (30%), Gaps = 37/316 (11%) Query: 63 YTKTFGYPPLTKILASFFGELLGQEIDPLRNV--LVTVGGYGALFTAFQALVDEGDEVII 120 Y G KI+ G P + + T GG GA+ +A + +DEGD +I Sbjct: 75 YAPIEGEKDYRKIVIDTL---FG-PYKPEGYISAIATPGGTGAIRSAIFSYLDEGDPLIC 130 Query: 121 IEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTK---- 176 + ++ Y + G + ++ + + Sbjct: 131 HDYYWAPYRKICEEFGRN-----------FKTFEFFTDDFAFNIDVYKEAIDEGIRDSDR 179 Query: 177 -ALVLNTP-NNPLGKVFSREELELVASLC------QQHDVVCITDEVYQWMVYDGHQHIS 228 A ++N+P NNP G S EE + V + + + I D Y DG Q Sbjct: 180 IASLINSPGNNPTGYSLSDEEWDEVITFLKEKAEDKDKKITLIVDVAYLEFAGDGDQQRK 239 Query: 229 IASLPGMWER---TLTIGSAGKTFSATGWKVGWVLG---PDHIMKHLRTVHQNSVFHCPT 282 R + S K+ +A G + G +G I++ +S + Sbjct: 240 FFEKFSNLPRNLFVVVAFSMSKSHTAYGLRSGAAVGISSSKEIIEEFEASLAHSARCNWS 299 Query: 283 QSQAAVAESFEREQLLFRQP--SSYFVQFPQAMQRCRDHMIRSLQSVGLKPIIPQGSYFL 340 A + + V ++ D + + + L I G +F Sbjct: 300 NGTHAAQNILIELERAENKKIYEQELVDLRNMLKSRADVFVTAAKENKLTMIPYFGGFFT 359 Query: 341 ITDISDFKRKMPDLPG 356 + DL Sbjct: 360 FIPTDKAFDIVKDLEK 375 >6C3C-A nrPDB Length = 413 Score = 89.1 bits (219), Expect = 3e-18, Method: Composition-based stats. Identities = 67/380 (17%), Positives = 120/380 (31%), Gaps = 41/380 (10%) Query: 47 VEAFQHAVSGDFMLNQYTKTFGYPPL--TKILASFFGELLGQEIDPLRNVLVTVGGYGAL 104 A Q ++ Y G + +FF +++ + Sbjct: 59 QSASQQSIVSRLPQLWYEAEEGLQATYEKRFTEAFFQLHRQPTALVKNKTMLSYAASIST 118 Query: 105 FTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDP 164 A L E V +IEP FD + V L P S + +D Sbjct: 119 MVAGMFLKKERLAVTLIEPCFDNLYDVLANMD-----VPLYPI-------DESVFYDVDR 166 Query: 165 MELAGKFTSRTKALVLNTPNNPLGKVF---SREELELVASLCQQHDVVCITDEVYQWMVY 221 + + RT AL L PNNP G R+ E V C+ HD + + D + Sbjct: 167 IYPELERRVRTDALFLVDPNNPTGFSLLRHGRKGFEEVVRFCKDHDKLLLIDFCFASFTL 226 Query: 222 DGHQHISIASLPGMWE----RTLTIGSAGKTFSATGWKVGWVLGPDHIMKHLRTVHQNSV 277 ++ + + E R L I GKT+ K + D I + + +H + + Sbjct: 227 -FEPELARFDMYELLENSGVRYLAIEDTGKTWPVQDAKCALITASDDIWETVYNLHTSVL 285 Query: 278 FHCPTQSQAAVAESFEREQLLFRQPSSYFVQFPQAMQRCRDHMIRSLQSVGLKPIIPQGS 337 + + Q + + + + R R+ ++L L+ P Sbjct: 286 LNVSPFVLNML------TQYVRDSAADRLASVREVLTRNRECARKTLDGSILEYQEP--- 336 Query: 338 YFLITDISDFKRKMPDLPGAVDEPYDRRFVKWMIKNKGLVAIPVSIFYSVPHQKHFDHYI 397 + ++ F+ P+L V ++ G+ +P FY K D Y+ Sbjct: 337 -VVKVSVAWFRVDHPELTATD--------VHRLLSADGVYVLPGRYFYWSEPSK-GDAYV 386 Query: 398 RFCFVKDEATLQAMDEKLRK 417 R ++ R+ Sbjct: 387 RMALAREPEMFADAMALTRQ 406 >4WD2-A nrPDB Length = 408 Score = 89.1 bits (219), Expect = 3e-18, Method: Composition-based stats. Identities = 67/404 (16%), Positives = 114/404 (28%), Gaps = 33/404 (8%) Query: 1 MAKQLQARRLDGIDYNP------WVEFVKLASEHDVVNLGQG---FPDFPPP-DFAVEAF 50 MA + ID P E + VNL G + P AV Sbjct: 1 MAHHHHHHMFEHIDAYPGDPILTLNENFQKDPRDQKVNLSIGIYFDAEGRIPVMGAVREA 60 Query: 51 QHAVSGDFMLNQYTKTFGYPPLTKILASF-FGELLGQEIDPLRNVLVTVGGYGALFTAFQ 109 + A+ D Y G + S FG L T+GG GAL Sbjct: 61 ETALQRDSGPKPYLPMVGLAAYRDAVQSLVFGADHPARAAGRIATLQTLGGSGAL-KVGA 119 Query: 110 ALVD---EGDEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPME 166 + +V + +P ++ + + AG E + Sbjct: 120 DFLKRYFPDSQVWLSDPSWENHRFIFERAGFTVNTYP------YYDEATGGLKFDAMLAA 173 Query: 167 LAGKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQQHDVVCITDEVYQWMVYD-GHQ 225 + L +NP G + E + + + +++ D YQ Sbjct: 174 IDALPARSIVLLHACC-HNPTGVDLDEGQWEKLIDVIEARELLPFVDMAYQGFGAGLDAD 232 Query: 226 HISIASLPGMWERTLTIGSAGKTFSATGWKV-GWVLGPDHIMKHLRTVHQ-----NSVFH 279 ++ L TL S K FS G +V G + + R + Q S + Sbjct: 233 AFAVRELARRGVPTLVANSFSKNFSLYGERVGGLSVVCEDAAAAERVLGQLAGAVRSNYS 292 Query: 280 CPTQSQAAVAESFEREQLLFRQPSSYFVQFPQAMQRCRDHMIRSLQSV----GLKPIIPQ 335 P A V + L +Q + + R R + L+ L + Q Sbjct: 293 NPQTYGAKVVAAVLGTPALRKQWEEELSAMCRRIARMRQSIHDGLRDHVSGEALTRYVKQ 352 Query: 336 GSYFLITDISDFKRKMPDLPGAVDEPYDRRFVKWMIKNKGLVAI 379 F T +++ + V R + + + + Sbjct: 353 RGMFTYTGLTESQVDALREVHGVYILRSGRMCVAGLNDSNVGIV 396 >3EZ1-A nrPDB Length = 423 Score = 84.5 bits (207), Expect = 7e-17, Method: Composition-based stats. Identities = 67/400 (16%), Positives = 117/400 (29%), Gaps = 65/400 (16%) Query: 31 VNLGQGFP---DFPPPDFAVE--AFQHAVSGDFMLNQYTKT-FGYPPLTKILASFFGELL 84 +N+ +G P DF + + + L Y G P + A Sbjct: 28 LNMQRGQPADADFDLSNGLLTVLGAEDVRMDGLDLRNYPGGVAGLPSARALFA------- 80 Query: 85 GQEIDPLRNVLVTVGGY---GALFTAFQAL----------VDEGDEVIIIEPFFDCYEPM 131 G NVLV L F L + + ++I+ P +D + + Sbjct: 81 GYLDVKAENVLVWNNSSLELQGLVLTFALLHGVRGSTGPWLSQTPKMIVTVPGYDRHFLL 140 Query: 132 TMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVF 191 G + V ++ + LAG S L + T +NP G+ Sbjct: 141 LQTLGFELLTVDMQSDGPDVDAV----------ERLAGTDPSVKGILFVPTYSNPGGETI 190 Query: 192 SREELELVASL-CQQHDVVCITDEVY--QWMVYDGH----QHISIASLPGMWERTLTIGS 244 S E+ +A L D D+ Y +V + + +A G +R S Sbjct: 191 SLEKARRLAGLQAAAPDFTIFADDAYRVHHLVEEDRAEPVNFVVLARDAGYPDRAFVFAS 250 Query: 245 AGK-TFSATGWKVGWVLGPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFERE-QLLFRQP 302 K TF+ G G+V + ++ L QA + L Sbjct: 251 TSKITFAGAGL--GFVASSEDNIRWLSKYLGAQSIGPNKVEQARHVKFLTEYPGGLEGLM 308 Query: 303 SSYFVQFPQAMQRCRDHMIRSLQSVGLK--PIIPQGSYFLITDISDFKRKMPDLPGAVDE 360 + + + + L G +P+G YF+ D ++ Sbjct: 309 RDHAAIIAPKFRAVDEVLRAELGEGGEYATWTLPKGGYFISLDTAEPVADR--------- 359 Query: 361 PYDRRFVKWMIKNKGLVAIPVSIFYSVPHQKHFDHYIRFC 400 V + + G+ P Y H + +R Sbjct: 360 ------VVKLAEAAGVSLTPAGATYPAGQDPHNRN-LRLA 392 >1AY8-A nrPDB Length = 394 Score = 81.8 bits (200), Expect = 5e-16, Method: Composition-based stats. Identities = 51/318 (16%), Positives = 96/318 (30%), Gaps = 28/318 (8%) Query: 26 SEHDVVNLGQG---FPDFPPP--DFAVEAFQHAVSGDFMLNQYTKTFGYPPLTKILASF- 79 ++LG G P A Q + + Y G P K + Sbjct: 24 PRQGKIDLGVGVYKDATGHTPIMRAVHAAEQRMLETETTKT-YAGLSGEPEFQKAMGELI 82 Query: 80 FGELLGQEIDPLRNVLVTVGGYGALFTAFQA--LVDEGDEVIIIEPFFDCYEPMTMMAGG 137 G+ L E L TVGG GAL A + + + V + +P + + + G Sbjct: 83 LGDGLKSETTAT---LATVGGTGALRQALELARMANPDLRVFVSDPTWPNHVSIMNFMG- 138 Query: 138 RPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELE 197 + ++ + E + A K +NP G + ++ Sbjct: 139 ----LPVQTYRYFDAETRGVDFEGMKADLAAAKKGDMVLLHGCC--HNPTGANLTLDQWA 192 Query: 198 LVASLCQQHDVVCITDEVYQWMVYDGHQHISIAS--LPGMWERTLTIGSAGKTFSATGWK 255 +AS+ ++ + + D YQ DG + + + + L S K F + Sbjct: 193 EIASILEKTGALPLIDLAYQGFG-DGLEEDAAGTRLIASRIPEVLIAASCSKNFGIYRER 251 Query: 256 VGWVL------GPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQF 309 G +L + + + P A + + L + Sbjct: 252 TGCLLALCADAATRELAQGAMAFLNRQTYSFPPFHGAKIVSTVLTTPELRADWMAELEAV 311 Query: 310 PQAMQRCRDHMIRSLQSV 327 M R R+ + L+ + Sbjct: 312 RSGMLRLREQLAGELRDL 329 >3PD6-B nrPDB Length = 401 Score = 81.0 bits (198), Expect = 9e-16, Method: Composition-based stats. Identities = 62/380 (16%), Positives = 119/380 (31%), Gaps = 37/380 (9%) Query: 19 VEFVKLASEHDVVNLGQG-FPDFPPPDFAVEAFQHA---VSGDFMLNQYTKTFGYPPLTK 74 E K + +NLG G + D + + + + A ++ + +Y G K Sbjct: 19 TEAFKRDTNSKKMNLGVGAYRDDNGKPYVLPSVRKAEAQIAAKNLDKEYLPIGGLAEFCK 78 Query: 75 ILASFFGELLGQEIDPLRNVLV-TVGGYGAL---FTAFQALVDEGDEVIIIEPFFDCYEP 130 A + + R V V T+ G GAL + Q +V + +P + + P Sbjct: 79 ASAELALGENNEVLKSGRFVTVQTISGTGALRVGASFLQRFFKFSRDVFLPKPSWGNHTP 138 Query: 131 MTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKV 190 + AG + G ++ +++ L +NP G Sbjct: 139 IFRDAGMQL------QGYRYYDPKTCGFDFSGALEDISKIPEQSVLLLHACA-HNPTGVD 191 Query: 191 FSREELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIA--SLPGMWERTLTIGSAGKT 248 E+ + +AS+ ++ ++ D YQ + A S K Sbjct: 192 PRPEQWKEIASVVKKKNLFAFFDMAYQGFASGDGDKDAWAVRHFIEQGINVCLCQSYAKN 251 Query: 249 FSATGWKVG-WVLGPDHIMKHLRTVHQ-----NSVFHCPTQSQAAVAESFEREQLLFRQP 302 G +VG + + + R Q ++ P + A +A + L +Q Sbjct: 252 MGLYGERVGAFTVVCKDAEEAKRVESQLKILIRPLYSNPPLNGARIAATILTSPDLRKQW 311 Query: 303 SSYFVQFPQAMQRCRDHMIRSLQSVG----LKPIIPQGSYFLITDISDFKRKMPDLPGAV 358 + R ++ +L+ G + I Q F T L Sbjct: 312 LQEVKGMADRIISMRTQLVSNLKKEGSSHNWQHITDQIGMFCFTG----------LKPEQ 361 Query: 359 DEPYDRRFVKWMIKNKGLVA 378 E + F +M K+ + Sbjct: 362 VERLTKEFSVYMTKDGRISV 381 >4RKC-A nrPDB Length = 398 Score = 81.0 bits (198), Expect = 9e-16, Method: Composition-based stats. Identities = 60/399 (15%), Positives = 110/399 (27%), Gaps = 41/399 (10%) Query: 10 LDGIDYNP------WVEFVKLASEHDVVNLGQGF--------PDFPPPDFAVEAFQHAVS 55 + IDY VE + D VNLG G P A + +S Sbjct: 2 FERIDYYAGDPILGLVEKFAADNNPDKVNLGIGIYYDESGVMPVLDCVKIAEQRIADPIS 61 Query: 56 GDFMLNQYTKTFGYPPLTKILASF-FGELLGQEIDPLRNVLVTVGGYGALFTAFQALVD- 113 Y G P K FG+ D L + T+GG GAL + Sbjct: 62 PRP----YLPMAGLPGHRKGCQELLFGKDAPVLKDGLVATIATIGGSGAL-KVGAEFIHE 116 Query: 114 --EGDEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKF 171 + + +P + + + + + Sbjct: 117 WFPQSKCYVSDPTWGNHIAIFEGCDIEVGKYPYYDTATGGIKFDEMIAF------FETLN 170 Query: 172 TSRTKALVLNTPNNPLGKVFSREELELVASLCQQHDVVCITDEVYQWMVYD-GHQHISIA 230 L +NP G +RE+ + V ++ Q+ +++ D YQ D +I Sbjct: 171 KDDVLLLHPCC-HNPTGVDLTREQWDTVLNVIQERELIPFMDIAYQGFGEDMDSDAYAIR 229 Query: 231 SLPGMWERTLTIGSAGKTFSATGWKVGWVLGPDHIMKHLRTVHQNS------VFHCPTQS 284 M S K S G +VG + + V ++ P Sbjct: 230 KAVDMGLPLFVSNSFSKNLSLYGERVGGLSVVCPTVDETERVFGQLNSTVRRIYSSPPSH 289 Query: 285 QAAVAESFEREQLLFRQPSSYFVQFPQAMQRCRDHMIRSLQSV----GLKPIIPQGSYFL 340 V + + L Q ++ R + L++ + Q F Sbjct: 290 GGRVVDIVMNDAALHEQWVGEVYAMRDRIKSMRTKLKSVLEAKISGRNFDYLTAQNGMFS 349 Query: 341 ITDISDFKRKMPDLPGAVDEPYDRRFVKWMIKNKGLVAI 379 T ++ + + + + R + + + + Sbjct: 350 FTGLTPEQVERLQSEFGIYMISNSRMCVAGLNSSNIDYV 388 >4W5K-A nrPDB Length = 396 Score = 77.9 bits (190), Expect = 8e-15, Method: Composition-based stats. Identities = 54/312 (17%), Positives = 92/312 (29%), Gaps = 24/312 (7%) Query: 31 VNLGQGFPDFPPPD-FAVEAFQHAVSGDFMLNQYTKTFGYPPLTKILASF-FGELLGQEI 88 VNL G F +E + A G M Y G + FG Sbjct: 31 VNLSIGVYRDDADQPFVLECVKQATLGTNM--DYAPVTGIASFVEEAQKLCFGPTCAALR 88 Query: 89 DPLRNVLVTVGGYGALFT---AFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVSLK 145 D T+GG GAL V + + + + +E + AG S Sbjct: 89 DGRIASCQTLGGTGALRIGGDLLNRFVANCNRIYGPDVGYPNHESIFAKAGMELTPYS-Y 147 Query: 146 PGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQQ 205 P G + LD K + LV +NP G + ++ V + ++ Sbjct: 148 YDPATKGLNLAGMLECLD------KAPEGSVILVHACAHNPTGVDPTHDDWRQVCDVIKR 201 Query: 206 HDVVCITDEVYQWMVYDGHQHISI--ASLPGMWERTLTIGSAGKTFSATGWKVGWVLGP- 262 + + D YQ + + L M + S F G + G + Sbjct: 202 RNHIPFVDMAYQGFATGQLDYDAFVPRHLVDMVPNLIVAQSFSANFGLYGHRCGALHIST 261 Query: 263 ------DHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFPQAMQRC 316 ++ L + + + P V+ + QL Q + Sbjct: 262 ASAEEAKRLVSQLALLIRPMYSNPPLYGAWVVSSILKDPQLTALWKKE-LKQMSSRIAEV 320 Query: 317 RDHMIRSLQSVG 328 R ++ L++ G Sbjct: 321 RKRLVSELKACG 332 >1TAR-A nrPDB Length = 401 Score = 76.0 bits (185), Expect = 3e-14, Method: Composition-based stats. Identities = 58/380 (15%), Positives = 116/380 (30%), Gaps = 37/380 (9%) Query: 19 VEFVKLASEHDVVNLGQG-FPDFPPPDFAVEAFQHA---VSGDFMLNQYTKTFGYPPLTK 74 E K + +NLG G + D + + + A ++ M +Y G T+ Sbjct: 19 TEAFKRDTNSKKMNLGVGAYRDDNGKPYVLNCVRKAEAMIAAKKMDKEYLPIAGLADFTR 78 Query: 75 ILASFFGELLGQEIDPLRNVLV----TVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEP 130 A + R V V G Q +V + +P + + P Sbjct: 79 ASAELALGENSEAFKSGRYVTVQGISGTGSLRVGANFLQRFFKFSRDVYLPKPSWGNHTP 138 Query: 131 MTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKV 190 + AG + S ++ ++ K ++ L+ +NP G Sbjct: 139 IFRDAGLQLQAY------RYYDPKTCSLDFTGAMEDI-SKIPEKSIILLHACAHNPTGVD 191 Query: 191 FSREELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIA--SLPGMWERTLTIGSAGKT 248 +E+ + +AS+ ++ +++ D YQ + A + S K Sbjct: 192 PRQEQWKELASVVKKRNLLAYFDMAYQGFASGDINRDAWALRHFIEQGIDVVLSQSYAKN 251 Query: 249 FSATGWKVG-WVLGPDHIMKHLRTVHQNSV-----FHCPTQSQAAVAESFEREQLLFRQP 302 G + G + + + R Q + + P + A +A L ++ Sbjct: 252 MGLYGERAGAFTVICRDAEEAKRVESQLKILIRPMYSNPPMNGARIASLILNTPELRKEW 311 Query: 303 SSYFVQFPQAMQRCRDHMIRSLQSVG----LKPIIPQGSYFLITDISDFKRKMPDLPGAV 358 + R ++ +L+ G + I Q F T L Sbjct: 312 LVEVKGMADRIISMRTQLVSNLKKEGSSHNWQHITDQIGMFCFTG----------LKPEQ 361 Query: 359 DEPYDRRFVKWMIKNKGLVA 378 E + F +M K+ + Sbjct: 362 VERLTKEFSIYMTKDGRISV 381 >2CST-A nrPDB Length = 411 Score = 76.0 bits (185), Expect = 3e-14, Method: Composition-based stats. Identities = 66/369 (17%), Positives = 113/369 (30%), Gaps = 39/369 (10%) Query: 10 LDGIDYNPWVEFVKLASE------HDVVNLGQG--FPDFPPPDF--AVEAFQHAVSGDFM 59 + P V KL ++ VNLG G D P V + ++GD Sbjct: 5 FAAVPRAPPVAVFKLTADFREDGDSRKVNLGVGAYRTDEGQPWVLPVVRKVEQLIAGDGS 64 Query: 60 LNQ-YTKTFGYPPLTKILASFFGELLGQEIDPLRNV--LVTVGGYGAL---FTAFQALVD 113 LN Y G P AS + V + +GG GAL + + Sbjct: 65 LNHEYLPILGLPEFR-ANASRIALGDDSPAIAQKRVGSVQGLGGTGALRIGAEFLRRWYN 123 Query: 114 EGDEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFT- 172 + Y VF+ I+ ++ LD L Sbjct: 124 GNNNTAT-----PVYVSSPTWENHNSVFMDAGFKDIRTYRYWDAAKRGLDLQGLLDDMEK 178 Query: 173 -SRTKALVL-NTPNNPLGKVFSREELELVASLCQQHDVVCITDEVYQWMVYD--GHQHIS 228 +L +NP G + +E + +A++ ++ + D YQ + Sbjct: 179 APEFSIFILHACAHNPTGTDPTPDEWKQIAAVMKRRCLFPFFDSAYQGFASGSLDKDAWA 238 Query: 229 IASLPGMWERTLTIGSAGKTFSATGWKVG--WVLGPDH-----IMKHLRTVHQNSVFHCP 281 + S K F +VG V+G D ++ + + + + + P Sbjct: 239 VRYFVSEGFELFCAQSFSKNFGLYNERVGNLSVVGKDEDNVQRVLSQMEKIVRTTWSNPP 298 Query: 282 TQSQAAVAESFEREQLLFRQPSSYFVQFPQAMQRCRDHMIRSLQSVG----LKPIIPQGS 337 +Q VA + Q LF + + R + L+S+G I Q Sbjct: 299 SQGARIVATTLTSPQ-LFAEWKDNVKTMADRVLLMRSELRSRLESLGTPGTWNHITDQIG 357 Query: 338 YFLITDISD 346 F T ++ Sbjct: 358 MFSFTGLNP 366 >3BWN-A nrPDB Length = 391 Score = 74.5 bits (181), Expect = 8e-14, Method: Composition-based stats. Identities = 46/359 (12%), Positives = 96/359 (26%), Gaps = 54/359 (15%) Query: 70 PPLTKILASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQAL--VDEGDEVIIIE--PFF 125 P L + ++G R ++V G A AL + V ++ PF+ Sbjct: 71 PELEDAI-KDLHGVVGNAATEDRYIVVGTGSTQLCQAAVHALSSLARSQPVSVVAAAPFY 129 Query: 126 DCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNN 185 Y V W D ++ +PNN Sbjct: 130 STY-------------VEETTYVRSGMYKWEGDAWGFD--------KKGPYIELVTSPNN 168 Query: 186 PLGKVFSREELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTIGSA 245 P G + E V + + I D Y H + + + + + + Sbjct: 169 PDGTI-----RETVVNRPDDDEAKVIHDFAYY------WPHYT--PITRRQDHDIMLFTF 215 Query: 246 GKTFSATGWKVGWVLG-PDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSS 304 K G ++GW L + K + + +SQ A+ + + Sbjct: 216 SKITGHAGSRIGWALVKDKEVAKKMVEYIIVNSIGVSKESQVRTAKILNVLKETCKSE-- 273 Query: 305 YFVQFPQAMQRCRDHMIRSLQSVGLKPIIPQGSY----FLITDISDFKRKMPDLPGAVDE 360 + + R+ M + + + + ++ + + F + + P Sbjct: 274 --SESENFFKYGREMMKNRWEKLR-EVVKESDAFTLPKYPEAFCNYFGKSLESYPAFAWL 330 Query: 361 PYDRRFVKWMIKNKGLVAIPVSIFYSVPHQKHFDHYIRFCFVKDEATLQAMDEKLRKWK 419 ++ + K ++R + E E+L K Sbjct: 331 GTKEE--TDLVSELRRHKVMSRAGERCGSDKK---HVRVSMLSREDVFNVFLERLANMK 384 >4WB0-B nrPDB Length = 414 Score = 74.1 bits (180), Expect = 1e-13, Method: Composition-based stats. Identities = 58/363 (15%), Positives = 106/363 (29%), Gaps = 35/363 (9%) Query: 9 RLDGIDYNPWVEFVKLASEHDVV-----NLGQG----FPDFPPPDFAVEAFQHAVSGDFM 59 R I +LA NL G P P V + + + Sbjct: 14 RWQKIQGRAPDPIFELAKRAAAAKGPKANLVIGAYRDEQGLPYPLRVVRKAEQLLLDMNL 73 Query: 60 LNQYTKTFGYPPLTKILASFFGELLGQEIDPLRNVLV-TVGGYGALFT---AFQALVDEG 115 +Y GY P + G ++ V V T+ G GAL + D Sbjct: 74 NYEYLPISGYQPF---IDEAVKMTYGDTVELENLVAVQTLSGTGALSLGAKLLTHVFDAE 130 Query: 116 DEVIII-EPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSR 174 I + +P + + + AG + + G +++ ++ Sbjct: 131 KTPIYLADPTWPNHYSIVKAAGWKDIRTYAYYDHKTLGL-----DFEGMKKDILAAPDGS 185 Query: 175 TKALVLNTPNNPLGKVFSREELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIAS--L 232 L +NP G S+E+ +ASL D YQ + A+ Sbjct: 186 VFLLHQCA-HNPTGVDPSQEQWNEIASLMLAKHHQVFFDSAYQGYASGSLDTDAYAARLF 244 Query: 233 PGMWERTLTIGSAGKTFSATGWKVG---WVLGPDHIMKHLRTVHQNSV---FHCPTQSQA 286 L S K + G +L +++V + + + CP A Sbjct: 245 ARRGIEVLLAQSFSKNMGLYSERAGTLSLLLKDKTKRADVKSVMDSLIRAEYTCPPAHGA 304 Query: 287 AVAESFEREQLLFRQPSSYFVQFPQAMQRCRDHMIRSLQSV----GLKPIIPQGSYFLIT 342 +A L ++ + + ++ R + L + + +I Q F Sbjct: 305 RLAHLILSNNELRKEWEAELSAMAERIRTMRRTVYDELLRLQTPGRWEHVINQIGMFSFL 364 Query: 343 DIS 345 +S Sbjct: 365 GLS 367 >4H51-A nrPDB Length = 420 Score = 71.0 bits (172), Expect = 8e-13, Method: Composition-based stats. Identities = 62/370 (16%), Positives = 111/370 (30%), Gaps = 35/370 (9%) Query: 2 AKQLQARRLDGIDYNPWVEFVKLASEHDVV-----NLGQG----FPDFPPPDFAVEAFQH 52 A A R I LA NL G P P V + Sbjct: 13 AAMTTAERWQKIQAQAPDVIFDLAKRAAAAKGPKANLVIGAYRDEQGRPYPLRVVRKAEQ 72 Query: 53 AVSGDFMLNQYTKTFGYPPLTKILASFFGELLGQEIDPLRNVLV-TVGGYGALFT----A 107 + + +Y GY P + + G ++ V V T+ G GA+ Sbjct: 73 LLLDMNLDYEYLPISGYQPF---IDEAVKIIYGNTVELENLVAVQTLSGTGAVSLGAKLL 129 Query: 108 FQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMEL 167 + E + + +P + + + AG + + P S N++ ++ Sbjct: 130 TRVFDAETTPIYLSDPTWPNHYGVVKAAGWKNICTYAYYDP-----KTVSLNFEGMKKDI 184 Query: 168 AGKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQQHDVVCITDEVYQWMVYDGHQHI 227 L +NP G S+E+ +ASL D YQ Sbjct: 185 LAAPDGSVFILHQCA-HNPTGVDPSQEQWNEIASLMLAKHHQVFFDSAYQGYASGSLDTD 243 Query: 228 SIAS--LPGMWERTLTIGSAGKTFSATGWKVG---WVLGPDHIMKHLRTVHQNSV---FH 279 + A+ L S K + G +L +++V + + + Sbjct: 244 AYAARLFARRGIEVLLAQSFSKNMGLYSERAGTLSLLLKDKTKRADVKSVMDSLIREEYT 303 Query: 280 CPTQSQAAVAESFEREQLLFRQPSSYFVQFPQAMQRCRDHMIR---SLQSVG-LKPIIPQ 335 CP A +A L ++ + + ++ R + LQ+ G + +I Q Sbjct: 304 CPPAHGARLAHLILSNNELRKEWEAELSAMAERIRTMRRTVYDELLRLQTPGSWEHVINQ 363 Query: 336 GSYFLITDIS 345 F +S Sbjct: 364 IGMFSFLGLS 373 >4K2M-A nrPDB Length = 443 Score = 68.7 bits (166), Expect = 4e-12, Method: Composition-based stats. Identities = 47/332 (14%), Positives = 109/332 (32%), Gaps = 39/332 (11%) Query: 47 VEAFQHAVSGDFMLNQYTKTFGYPPLTKILASFFGELLGQEIDPLRNVLVTVGGYGALFT 106 VE + ++ ++T K+L+++ + V+ T G A+ Sbjct: 83 VEDILNTLTEVLPTGKFTSGPYLEQFEKVLSTYLHKRY---------VIATSSGTDAIMI 133 Query: 107 AFQAL-VDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPM 165 AL ++ GDEVI+ F E + +GG P++V + P + +DP Sbjct: 134 GLLALGLNPGDEVIMPANSFSATENAVLASGGVPIYVDINPQT-----------FCIDPD 182 Query: 166 ELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQQHDVVCITDEVYQWMVYDGHQ 225 ++ T TK ++ P+ +++ + + ++ + I D Q Sbjct: 183 KIEEAITPYTKFIL------PVHLYGKHSDMQHIRQIANRYKLKVIED---------ACQ 227 Query: 226 HISIASLPGMWERTLTIGSAGKTFSATGWKVGWVLGPDHIMKHLRTVHQNSVFHCPTQSQ 285 I + L + T + K F G K G + + + F +++ Sbjct: 228 GIGLTDLGKYADITTLSFNPYKNFGVCG-KAGAIATDNEELAKKCIQFSYHGFEVNVKNK 286 Query: 286 AAVAESFEREQLLFRQPSSYFVQFPQAMQRCRDHMIRSLQSVGLKPIIPQGSYFLITDIS 345 + F + + + + + + + + Y + ++S Sbjct: 287 KVINFGFNSKMDNLQAAIG-LERMKYLSLNNFKRLFLADRYITQLAELQNKGYIELPELS 345 Query: 346 DFKRKMPDLPGAVDEPYDRRFVKWMIKNKGLV 377 + P V + + ++ G+ Sbjct: 346 EDHVWHL-FPIKVRTEDRADIMTKLNEDFGVQ 376 >2X8U-A nrPDB Length = 412 Score = 67.5 bits (163), Expect = 9e-12, Method: Composition-based stats. Identities = 38/288 (13%), Positives = 77/288 (26%), Gaps = 30/288 (10%) Query: 43 PDFAVEAFQHAVSGDFMLNQYTKTFGYPPLTKILASFFGELLGQEIDPLRNVLVTVGGYG 102 PD Q G K E G E ++ + G Y Sbjct: 61 PDVIAAGKQALDEFGSGTTGSRVLNGTYQGHKACEDALKEFYGTE----HAIVFSTG-YQ 115 Query: 103 ALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQL 162 A L +GD +I+ + V + LG Sbjct: 116 ANLGMISTLAGKGDYIILDADSHASIYDGCWLGDAEIVRFRHNSVEDLDKRLGRLPAEAG 175 Query: 163 DPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQQHDVVCITDEVYQWMVYD 222 + L G ++ + L+ + ++ ++H + + DE + + Sbjct: 176 KLVVLEGVYS----------------MMGDIAPLQEMVAVSKKHGAMILVDEAHGMGFFG 219 Query: 223 GHQHISIASLPGMWERTLTIGSAGKTFSATGWKVGWVLGPDHIMKHLRTVHQNSVFHCPT 282 H + +G+ K+ G G+ + + LR V + VF Sbjct: 220 EHGRGVFEEAGVEADVDFVVGTFSKSVGTVG---GFCVSNHPKFEVLRLVCRPYVFTASL 276 Query: 283 QSQAAVAESFEREQLLFRQPSSYFVQFPQAMQRCRDHMIRSLQSVGLK 330 + +L+ + + + + L+ +G K Sbjct: 277 PPSVVATAATSIRKLMHAGDK------RAHLWKNSRRLHQGLRDMGYK 318 >3MEB-A nrPDB Length = 448 Score = 67.1 bits (162), Expect = 1e-11, Method: Composition-based stats. Identities = 58/381 (15%), Positives = 119/381 (31%), Gaps = 40/381 (10%) Query: 26 SEHDVVNLGQG-FPDFPPPDFAVEAFQHA---VSGDFML--NQYTKTFGYPPLTKILASF 79 + VNLG G + D + + A + A +S D +Y G+P + A F Sbjct: 47 TNPKKVNLGVGAYRDESGKPWILPAVKEAEAIISSDLSKYNKEYPPVAGFPLFLEA-AQF 105 Query: 80 FGELLGQEIDPLRNVLVTV----GGYGALFTAFQ--ALVDEGDEVIIIEPFFDCYEPMTM 133 + G++ + + G G+L F+ L E + + + + Sbjct: 106 L--MFGKDSKAAQEGRIASCQSLSGTGSLHIGFEFLHLWMPKAEFYMPSTTWPNHYGIYD 163 Query: 134 MAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTS-RTKALVL--NTPNNPLGKV 190 VF LK + L ++D S K++ L +NP G Sbjct: 164 K-----VFNKLKVPYKEYTYLRKDGELEIDFSNTKKDIQSAPEKSIFLFHACAHNPSGID 218 Query: 191 FSREELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIAS--LPGMWERTLTIGSAGKT 248 F+ + + + + ++ + D YQ + + A L S K Sbjct: 219 FTEAQWKELLPIMKEKKHIAFFDSAYQGFATGSFEADAFAVRMFVDAGVEVLVAQSFSKN 278 Query: 249 FSATGWKVGWV-LGPDHIMKHLRT-------------VHQNSVFHCPTQSQAAVAESFER 294 F G ++G + + + + + + A + + Sbjct: 279 FGLYGERIGCLHVVHAGVEGSVEKNKALSAAMVSGMTLQIRKTWSMSAIHGAYIVQVIVH 338 Query: 295 EQLLFRQPSSYFVQFPQAMQRCRDHMIRSLQSVGLKPIIPQGSYFLITDISDFKRKMPDL 354 ++ L + + + R R + SL +G++ I Sbjct: 339 DKRLLQMFYDNVKEMSARIHRMRSLLHASLAKRKTPGPGSKGTWDHILTAIGMFTFTGLT 398 Query: 355 PGAVDEPYDRRFVKWMIKNKG 375 P VD + ++ +++K G Sbjct: 399 PEHVDYLKE-KWSIYLVKAGG 418 >1YAA-A nrPDB Length = 412 Score = 66.8 bits (161), Expect = 2e-11, Method: Composition-based stats. Identities = 63/404 (15%), Positives = 120/404 (29%), Gaps = 42/404 (10%) Query: 10 LDGIDYNPWVEFVKLASEHDV------VNLGQG--FPDFPPPDFA--VEAFQHAVSGDFM 59 + I+ P + + V+LG G D P V+A + + D Sbjct: 5 FNNIELLPPDALFGIKQRYGQDQRATKVDLGIGAYRDDNGKPWVLPSVKAAEKLIHNDSS 64 Query: 60 LNQ-YTKTFGYPPLTKILASFFGELLGQEIDPLRNV-LVTVGGYGALFTAFQALVD--EG 115 N Y G P LT A + R + + ++ G GAL + + Sbjct: 65 YNHEYLGITGLPSLTSNAAKIIFGTQSDALQEDRVISVQSLSGTGALHISAKFFSKFFPD 124 Query: 116 DEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRT 175 V + +P + + + G + ++ +L N A + Sbjct: 125 KLVYLSKPTWANHMAIFENQGLKTATYPYWANETKSLDLNGFLN--------AIQKAPEG 176 Query: 176 KALVLNT-PNNPLGKVFSREELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPG 234 VL++ +NP G + E+ + + + + D YQ + A G Sbjct: 177 SIFVLHSCAHNPTGLDPTSEQWVQIVDAIASKNHIALFDTAYQGFATGDLDKDAYAVRLG 236 Query: 235 M-----WERTLTIGSAGKTFSATGWKVGWV-----------LGPDHIMKHLRTVHQNSVF 278 + S K G +VG + L + ++ V Sbjct: 237 VEKLSTVSPVFVCQSFAKNAGMYGERVGCFHLALTKQAQNKTIKPAVTSQLAKIIRSEVS 296 Query: 279 HCPTQSQAAVAESFEREQLLFRQPSSYFVQFPQAMQRC---RDHMIRSLQSVGLKPIIPQ 335 + P VA+ E +L + + + RDH+++ I+ Q Sbjct: 297 NPPAYGAKIVAKLLETPELTEQWHKDMVTMSSRITKMRHALRDHLVKLGTPGNWDHIVNQ 356 Query: 336 GSYFLITDISDFKRKMPDLPGAVDEPYDRRFVKWMIKNKGLVAI 379 F T ++ K + AV R + + + Sbjct: 357 CGMFSFTGLTPQMVKRLEETHAVYLVASGRASIAGLNQGNVEYV 400 >1M6S-A nrPDB Length = 347 Score = 66.8 bits (161), Expect = 2e-11, Method: Composition-based stats. Identities = 46/301 (15%), Positives = 90/301 (29%), Gaps = 48/301 (15%) Query: 46 AVEAFQHAVSGDFMLNQYTKTFGYPPLTKILASFFGELLGQEIDPLRNVLVTVGGYGALF 105 E + A++ + + +G P L E G L G Sbjct: 16 PTEEMRKAMAQAEVGD---DVYGEDPTINELERLAAETFG-----KEAALFVPSGTMGNQ 67 Query: 106 TAFQALVDEGDEVIIIEP---FFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQL 162 + A GDEVI+ F+ M +++G P V K G + Sbjct: 68 VSIMAHTQRGDEVILEADSHIFWYEVGAMAVLSGVMPHPVPGKNGA-------------M 114 Query: 163 DPMELAGKFTSR------TKALVLNTPNNPLG-KVFSREELELVASLCQQHDVVCITDEV 215 DP ++ R T + + +N G +V E ++ + ++ ++H + D Sbjct: 115 DPDDVRKAIRPRNIHFPRTSLIAIENTHNRSGGRVVPLENIKEICTIAKEHGINVHIDGA 174 Query: 216 YQWMVYDGHQHISIASLPGMWERTLTIGSAGKTFSATGWKVG-WVLGPDHIMKHLRTVHQ 274 + + + G + + K A VG V+G ++ R + Sbjct: 175 -RIFNASIASGVPVKEYAGYADSVMFC--LSKGLCAP---VGSVVVGDRDFIERARKARK 228 Query: 275 NSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFPQAMQRCRDHMIRSLQSVGLKPIIP 334 A A +++ R + + L+ +G P Sbjct: 229 MLGGGMRQAGVLAAAGIIALTKMVDRLKEDH---------ENARFLALKLKEIGYSV-NP 278 Query: 335 Q 335 + Sbjct: 279 E 279 >5C6U-A nrPDB Length = 435 Score = 66.4 bits (160), Expect = 2e-11, Method: Composition-based stats. Identities = 56/435 (12%), Positives = 106/435 (24%), Gaps = 77/435 (17%) Query: 1 MAKQLQARRLDGIDYNPWVEFVKLASEHDVVNLGQGFPDFPPPDFAVEAFQHAVS----- 55 M L + L + ++ L ++L +G P D + + Sbjct: 1 MFDSLSPQELAALHARHQQDYAALQGMKLALDLTRGKPSAEQLDLSNQLLSLPGDDYRDP 60 Query: 56 GDFMLNQYTKTFGYPPLTKILASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQALV--- 112 Y G P L I A G + N++ L A Sbjct: 61 EGTDTRNYGGQHGLPGLRAIFAELLG-------IAVPNLIAGNNSSLELMHDIVAFSMLY 113 Query: 113 ------------DEGDEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNW 160 +G + + P +D + +T G + + + Sbjct: 114 GGVDSPRPWIQEQDGIKFLCPVPGYDRHFAITETMGIEMIPIPMLQDGPD---------- 163 Query: 161 QLDPMELAGKFTSRTKAL-VLNTPNNPLGKVFSREELELVASL-CQQHDVVCITDEVYQ- 217 +D +E K + + NP G +S E + + + D D Y Sbjct: 164 -VDLIEELVAVDPAIKGMWTVPVFGNPSGVTYSWETVRRLVQMRTAAPDFRLFWDNAYAV 222 Query: 218 -WMVYDGHQHISIASL---PGMWERTLTIGSAGKTFSATGWKVGWVLGPDHI-------M 266 + D + + + L G R S K + + G + Sbjct: 223 HTLTLDFPRQVDVLGLAAKAGNPNRPYVFASTSK--------ITFAGGGVSFFGGSLGNI 274 Query: 267 KHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFPQAMQRCRDHMIRSLQS 326 +Q F + + + + + L Sbjct: 275 AWYLQYAGKKSIGPDKVNQLRHLRFFGDADGVRLHMLRHQQILAPKFALVAEVLDQRLSE 334 Query: 327 VGL-KPIIPQGSYFLITDISDFKRKMPDLPGAVDEPYDRRFVKWMIKNKGLVAIPVSIFY 385 + P+G YF+ D+ P R + K+ G+ + Sbjct: 335 SKIASWTEPKGGYFISLDV---------------LPGTARRTVALAKDVGIAVTEAGASF 379 Query: 386 SVPHQKHFDHYIRFC 400 D IR Sbjct: 380 PYRKDPD-DKNIRIA 393 >6EZL-A nrPDB Length = 404 Score = 65.6 bits (158), Expect = 3e-11, Method: Composition-based stats. Identities = 55/325 (16%), Positives = 90/325 (27%), Gaps = 28/325 (8%) Query: 21 FVKLASEHDVVNLGQGF----PDFPPPDFAVEAFQHAVSGDFMLNQYTKTFGYPPLTKIL 76 K A E +L G P P V + + +Y GY P + Sbjct: 24 VAKKAPEPKA-DLIIGAYRDAEGHPYPLNVVRKAEQRLLEMNADKEYLPMSGYAPF---I 79 Query: 77 ASFFGELLGQEIDPLRNVLVTVG----GYGALFTAFQALVDEGDE-VIIIEPFFDCYEPM 131 G + NV+ G G ++ F A V D V I +P + + + Sbjct: 80 EESLKIAYGDSV-ARENVVGIQGLSGTGSLSIGACFLARVLSRDTPVYISDPTWPNHYAV 138 Query: 132 TMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVF 191 A L+ + ++ +L G L +NP G Sbjct: 139 MAAANLT----DLRKYRYYDNAKRC-IDFDGLLEDLNGAPEGSIVILHACA-HNPTGMDP 192 Query: 192 SREELELVASLCQQHDVVCITDEVYQWMVYD--GHQHISIASLPGMWERTLTIGSAGKTF 249 + E+ + + Q ++ D YQ + SI L S K Sbjct: 193 THEQWAKILEVFQARRLIPFFDSAYQGYATGSLDNDAYSIRLFARQGMEMLLAQSYSKNM 252 Query: 250 SATGWKVG---WVLGPDH---IMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPS 303 +VG V ++K S + P A VA + L Sbjct: 253 GLYAERVGVCSIVTANPKKAPLIKSQLETIVRSQYSTPPAHGARVAYLVLSDPELRAGWE 312 Query: 304 SYFVQFPQAMQRCRDHMIRSLQSVG 328 + R + L+ +G Sbjct: 313 QELRVMSTRVLEMRQALYDGLKRLG 337 >4EFF-A nrPDB Length = 420 Score = 65.6 bits (158), Expect = 3e-11, Method: Composition-based stats. Identities = 60/373 (16%), Positives = 115/373 (30%), Gaps = 27/373 (7%) Query: 26 SEHDVVNLGQGF-PDFPPPDFAVEAFQHAVSGDFML---NQYTKTFGYPPLTKILASFFG 81 + VNLG G + + A + A Y G + Sbjct: 47 TRPTKVNLGVGVYTNEDGKIPLLRAVRDAEKARVEAGLPRGYLPIDGIAAYDASVQKLLL 106 Query: 82 ELLGQEIDPLRNVLV-TVGGYGALFTA--FQALVDEGDEVIIIEPFFDCYEPMTMMAGGR 138 I R V +GG GAL F ++ +V I +P ++ + + MAG Sbjct: 107 GDDSPLIAAGRVVTAQALGGTGALKIGADFLRTLNPKAKVAISDPSWENHRALFDMAGFE 166 Query: 139 PVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELEL 198 V + N+ L G + T ++ +NP G + + Sbjct: 167 VVAYP------YYDAKTNGVNFDGMLAALNG-YEPGTIVVLHACCHNPTGVDLNDAQWAQ 219 Query: 199 VASLCQQHDVVCITDEVYQWMVYD-GHQHISIASLPGMWERTLTIGSAGKTFSATGWKVG 257 V + + +V D YQ ++ S K+FS G +VG Sbjct: 220 VVEVVKARRLVPFLDIAYQGFGESIEADAAAVRLFAAANLNVFVSSSFSKSFSLYGERVG 279 Query: 258 WVLG-------PDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFP 310 + ++ L+ V + + + PT A VA +L + Sbjct: 280 ALSIITDSKDEAARVLSQLKRVIRTNYSNPPTHGGAIVAAVLASPELRASWVQE-LGEMR 338 Query: 311 QAMQRCRDHMIRSLQSVGLKP----IIPQGSYFLITDISDFKRKMPDLPGAVDEPYDRRF 366 ++ R+ ++ L++ G++ I Q F + ++ + + R Sbjct: 339 DRIRAMRNGLVERLKAAGIERDFSFINAQRGMFSYSGLTSAQVDRLREEFGIYAVSTGRI 398 Query: 367 VKWMIKNKGLVAI 379 + + L + Sbjct: 399 CVAALNTRNLDVV 411 >3NYS-A nrPDB Length = 367 Score = 65.2 bits (157), Expect = 5e-11, Method: Composition-based stats. Identities = 35/171 (20%), Positives = 55/171 (32%), Gaps = 27/171 (15%) Query: 46 AVEAFQHAVSGDFMLNQYTKTFGYPPLTKILASFFGELLGQEIDPLRNVLVTVGGYGALF 105 + + QY L LA F G + G AL Sbjct: 14 IKDKIDAGIQRVLRHGQYILGPEVTELEDRLADFVGAKY---------CISCANGTDALQ 64 Query: 106 TAFQAL-VDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDP 164 AL V GDEVI + + G +PV+V + P + LDP Sbjct: 65 IVQMALGVGPGDEVITPGFTYVATAETVALLGAKPVYVDIDPRT-----------YNLDP 113 Query: 165 MELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQQHDVVCITDEV 215 L T RTKA++ P+ + + + ++ ++ + I D Sbjct: 114 QLLEAAITPRTKAII------PVSLYGQCADFDAINAIASKYGIPVIEDAA 158 >3VK2-A nrPDB Length = 398 Score = 64.8 bits (156), Expect = 6e-11, Method: Composition-based stats. Identities = 46/268 (17%), Positives = 77/268 (28%), Gaps = 38/268 (14%) Query: 39 DFPPPDFAVEAFQHAVSGDFMLNQYTKTFGYPPLTKILASFFGELLGQEIDPLRNVLVTV 98 FP ++ F +G F T +AS G G + Sbjct: 39 TFPTVEYGAACFAGEQAGHFYSRISNPTLNLLEAR--MASLEGGEAGLAL---------A 87 Query: 99 GGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSS 158 G GA+ + L+ GDEV++ + G V L+ + Sbjct: 88 SGMGAITSTLWTLLRPGDEVLLGNTLYGHTFAFLH-HGIGEFGVKLRHVDMA-------- 138 Query: 159 NWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQQHDVVCITDEVYQW 218 D L T T+ + +P NP ++ VA + ++H + D Y Sbjct: 139 ----DLQALEAAMTPATRVIYFESPANP---NMHMADIAGVAKIARKHGATVVVDNTYC- 190 Query: 219 MVYDGHQHISIASLPGMWERTLTIGSAGKTFSATG-WKVGWVLGPDHIMKHLRTVHQNSV 277 P L + SA K S G G V+G ++ + + Sbjct: 191 --------TPYLQRPLELGADLVVHSATKYLSGHGDITAGIVVGSQALVDRI-RLQGLKD 241 Query: 278 FHCPTQSQAAVAESFEREQLLFRQPSSY 305 S A + L + + Sbjct: 242 MTGAVLSPHDAALLMRGIKTLNLRMDRH 269 >3DR4-A nrPDB Length = 391 Score = 64.8 bits (156), Expect = 6e-11, Method: Composition-based stats. Identities = 49/329 (14%), Positives = 98/329 (29%), Gaps = 40/329 (12%) Query: 78 SFFGELLGQEIDPLRNVLVTVGGYGALFTAFQAL-VDEGDEVIIIEPFFDCYEPMTMMAG 136 F + G + + + G AL A A+ + GDEVI+ + G Sbjct: 63 KAFADYCGVK-----HAIACNNGTTALHLALVAMGIGPGDEVIVPSLTYIASANSVTYCG 117 Query: 137 GRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREEL 196 PV V P + LD +L T RTKA++ P + G++ + Sbjct: 118 ATPVLVDNDPRT-----------FNLDAAKLEALITPRTKAIM---PVHLYGQICD---M 160 Query: 197 ELVASLCQQHDVVCITDEVYQ-WMVYDGHQHISIASLPGMWERTLTIGSAGKTFSATGWK 255 + + + ++H+++ I D Y G + S+ T G TG Sbjct: 161 DPILEVARRHNLLVIEDAAEAVGATYRGKKSGSLGD-------CATFSFFGNAIITTGEG 213 Query: 256 VGWVLGPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFPQAMQR 315 G + D + + + + + R + ++ Sbjct: 214 -GMITTNDDDLAAKMRLLRGQGMDPNRRYWFPIVGFNYRMTNIQAAIGLAQLERVDEHLA 272 Query: 316 CRDHMIR----SLQSVGLKPIIPQ----GSYFLITDISDFKRKMPDLPGAVDEPYDRRFV 367 R+ ++ L +G + P G + + V + D + Sbjct: 273 ARERVVGWYEQKLARLGNRVTKPHVALTGRHVFWMYTVRLGEGLSTTRDQVIKDLDALGI 332 Query: 368 KWMIKNKGLVAIPVSIFYSVPHQKHFDHY 396 + + +P + K + Sbjct: 333 ESRPVFHPMHIMPPYAHLATDDLKIAEAC 361 >3A2B-A nrPDB Length = 398 Score = 64.4 bits (155), Expect = 9e-11, Method: Composition-based stats. Identities = 53/391 (13%), Positives = 124/391 (31%), Gaps = 64/391 (16%) Query: 42 PPDFAVEAFQHAVSG-DFMLNQYTKTFGYPPLTKILASFFGELLGQEIDPLRNVLVTVGG 100 ++A Q A+ G + L +G+E +L + G Sbjct: 58 TDTRIIKAAQDALEKYGTGCAGSRFLNGTLDIHVELEEKLSAYVGKEA----AILFSTG- 112 Query: 101 YGALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNW 160 + + L+ D +++ E + ++ + + Sbjct: 113 FQSNLGPLSCLMGRNDYILLDERDHASIIDGSRLSFSKVIKYGHNNMEDLR--------- 163 Query: 161 QLDPMELAGKFTSRTKALVLNTPNNPLGKVFSRE----ELELVASLCQQHDVVCITDEVY 216 +L+ K + +FS E L + S+ + D + D+ + Sbjct: 164 ----AKLSRLPEDSAKLIC-------TDGIFSMEGDIVNLPELTSIANEFDAAVMVDDAH 212 Query: 217 QWMVYDGHQHISIASLPGMWERTLTIGSAGKTFSATGWKVGWVLGPDHIMKHLRTVHQNS 276 V + + + L +G+ K+ ++ G G+V G ++ + S Sbjct: 213 SLGVIGHKGAGTASHFGLNDDVDLIMGTFSKSLASLG---GFVAGDADVID-FLKHNARS 268 Query: 277 VFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFPQAMQRCRDHMIRSLQSVGLKPIIPQG 336 V + + A+VA + + +++ +P + + + + D+ L G Sbjct: 269 VMFSASMTPASVASTLKALEIIQNEP-----EHIEKLWKNTDYAKAQLLDHGFDL----- 318 Query: 337 SYFLITDISDFKRKMPDLPGAVDEPYDRRFVKWMIKNKGLVAIPVSIFYSVPHQKHFDHY 396 + P LP + +V M+++ G+ PV P + Sbjct: 319 ----------GATESPILPIFIRSNEKTFWVTKMLQDDGVFVNPV----VSPAVPAEESL 364 Query: 397 IRFCFVKD------EATLQAMDEKLRKWKVE 421 IRF + + ++ M + ++ +VE Sbjct: 365 IRFSLMATHTYDQIDEAIEKMVKVFKQAEVE 395 >3II0-A nrPDB Length = 422 Score = 63.7 bits (153), Expect = 1e-10, Method: Composition-based stats. Identities = 59/345 (17%), Positives = 113/345 (32%), Gaps = 39/345 (11%) Query: 31 VNLGQGFPDFPPPDF------AVEAFQHAVSGDFMLNQ-YTKTFGYPPLTKILASFFGEL 83 VNLG G + D V+ + ++ D LN Y G AS Sbjct: 22 VNLGVG--AYRTDDCHPWVLPVVKKVEQKIANDNSLNHEYLPILGLAEFR-SCASRLALG 78 Query: 84 LGQEIDPLRNV--LVTVGGYGAL-----FTA--FQALVDEGDEVIIIEPFFDCYEPMTMM 134 + V + ++GG GAL F A + ++ V + P ++ + + Sbjct: 79 DDSPALKEKRVGGVQSLGGTGALRIGADFLARWYNGTNNKNTPVYVSSPTWENHNAVFSA 138 Query: 135 AGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSRE 194 AG + ++ + E + Q +L L +NP G + E Sbjct: 139 AGFK----DIRSYRYWDAEK-RGLDLQGFLNDLENAPEFSIVVLHACA-HNPTGIDPTPE 192 Query: 195 ELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIAS--LPGMWERTLTIGSAGKTFSAT 252 + + +AS+ + + D YQ + + A S K F Sbjct: 193 QWKQIASVMKHRFLFPFFDSAYQGFASGNLERDAWAIRYFVSEGFEFFCAQSFSKNFGLY 252 Query: 253 GWKVG--WVLGPDH-----IMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSY 305 +VG V+G + ++ + + + + + P Q VA + + LF + + Sbjct: 253 NERVGNLTVVGKEPESILQVLSQMEKIVRITWSNPPAQGARIVASTLSNPE-LFEEWTGN 311 Query: 306 FVQFPQAMQRCRDHMIRSLQSVG----LKPIIPQGSYFLITDISD 346 + R + L+++ I Q F T ++ Sbjct: 312 VKTMADRILTMRSELRARLEALKTPGTWNHITDQIGMFSFTGLNP 356 >4PIW-A nrPDB Length = 396 Score = 63.7 bits (153), Expect = 2e-10, Method: Composition-based stats. Identities = 63/387 (16%), Positives = 125/387 (32%), Gaps = 55/387 (14%) Query: 40 FPPPDFA---VEAFQHAVSGDFMLNQYTKTFGYPPLTKILASFFGELLGQEIDPLRNVLV 96 F P ++ Q A+ + G T+ + + G VL+ Sbjct: 24 FNAPPVVGTELDYMQSAMGSGKLC-------GDGGFTRRCQQWLEQRFGSA-----KVLL 71 Query: 97 TVGGYGALFTAFQAL-VDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELG 155 T +L A L + GDEVI+ F ++ G + VFV ++P + Sbjct: 72 TPSCTASLEMAALLLDIQPGDEVIMPSYTFVSTANAFVLRGAKIVFVDVRPDTMN----- 126 Query: 156 SSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQQHDVVCITDEV 215 +D + T +T+ +V P+ E++ + +L ++H++ + D Sbjct: 127 ------IDETLIEAAITDKTRVIV------PVHYAGVACEMDTIMALAKKHNLFVVEDAA 174 Query: 216 YQWM-VYDGHQHISIASLPGMWERTLTIGSA--GKTFSATGWKVGWVLGPDHIMKHLRTV 272 M Y G +I + S K ++A G G L D + + Sbjct: 175 QGVMSTYKGRALGTIGHIG--------CFSFHETKNYTAGGEG-GATLINDKALIERAEI 225 Query: 273 HQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFPQAMQRCRDHMIR---SLQSVGL 329 + + + V + R+ S + A D + + +L Sbjct: 226 IREKGTNRSQFFRGQVDKYTWRDIGSSYLMSDLQAAYLWAQLEAADRINQQRLALWQNYY 285 Query: 330 KPIIP--QGSYFLITDISDFKRKMPDLP-GAVDEPYDRRFVKWMIKNKGL----VAIPVS 382 + P + + I D + + + + DR + +K + IP+ Sbjct: 286 DALAPLAKAGRIELPSIPDGCVQNAHMFYIKLRDIDDRSALINFLKEAEIMAVFHYIPLH 345 Query: 383 IFYSVPHQKHFDHYIRFCFVKDEATLQ 409 + H F R+ + E L+ Sbjct: 346 GCPAGEHFGEFHGEDRYTTKESERLLR 372 >2C81-A nrPDB Length = 418 Score = 62.5 bits (150), Expect = 3e-10, Method: Composition-based stats. Identities = 33/147 (22%), Positives = 58/147 (39%), Gaps = 23/147 (15%) Query: 68 GYPPLTKILASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQAL-VDEGDEVIIIEPFFD 126 G + + A F + G + T G AL A +AL + EGDEVI+ + Sbjct: 39 GEESMERKFAKAFADFNGVPY-----CVPTTSGSTALMLALEALGIGEGDEVIVPSLTWI 93 Query: 127 CYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNP 186 + PVFV + + + +DP + T +TKA++ P Sbjct: 94 ATATAVLNVNALPVFVDV-----------EADTYCIDPQLIKSAITDKTKAII------P 136 Query: 187 LGKVFSREELELVASLCQQHDVVCITD 213 + S ++ + + Q+H++ I D Sbjct: 137 VHLFGSMANMDEINEIAQEHNLFVIED 163 >5TON-A nrPDB Length = 414 Score = 62.1 bits (149), Expect = 4e-10, Method: Composition-based stats. Identities = 58/344 (16%), Positives = 106/344 (30%), Gaps = 37/344 (10%) Query: 31 VNLGQGFPDFPPPDF------AVEAFQHAVSGDFMLNQ-YTKTFGYPPLTKILASFFGEL 83 VNLG G + D V + ++ + LN Y G AS Sbjct: 35 VNLGVG--AYRTDDCQPWVLPVVRKVEQRIANNSSLNHEYLPILGLAEFR-TCASRLALG 91 Query: 84 LGQEIDPLRNV--LVTVGGYGALFTAFQAL------VDEGDE-VIIIEPFFDCYEPMTMM 134 + V + ++GG GAL + L + D V + P ++ + Sbjct: 92 DDSPALQEKRVGGVQSLGGTGALRIGAEFLARWYNGTNNKDTPVYVSSPTWENLNGVFTT 151 Query: 135 AGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSRE 194 AG + ++ + E + Q +L L +NP G + E Sbjct: 152 AGFK----DIRSYRYWDTEK-RGLDLQGFLSDLENAPEFSIFVLHACA-HNPTGTDPTPE 205 Query: 195 ELELVASLCQQHDVVCITDEVYQWMVYDG--HQHISIASLPGMWERTLTIGSAGKTFSAT 252 + + +AS+ ++ + D YQ +I S K F Sbjct: 206 QWKQIASVMKRRFLFPFFDSAYQGFASGNLEKDAWAIRYFVSEGFELFCAQSFSKNFGLY 265 Query: 253 GWKVG----WVLGPDHIMKHLRTVHQ--NSVFHCPTQSQAAVAESFEREQLLFRQPSSYF 306 +VG PD I++ L + + + P A + + LF + + Sbjct: 266 NERVGNLTVVAKEPDSILRVLSQMQKIVRVTWSNPPAQGARIVARTLSDPELFHEWTGNV 325 Query: 307 VQFPQAMQRCRDHMIRSLQSVG----LKPIIPQGSYFLITDISD 346 + R + L+++ I Q F T ++ Sbjct: 326 KTMADRILSMRSELRARLEALKTPGTWNHITDQIGMFSFTGLNP 369 >3K7Y-A nrPDB Length = 405 Score = 62.1 bits (149), Expect = 4e-10, Method: Composition-based stats. Identities = 44/312 (14%), Positives = 89/312 (28%), Gaps = 27/312 (8%) Query: 31 VNLGQG-----FPDFPPPDFAVEAFQHAVSGDFMLNQYTKTFGYPPLTKILASFFGELLG 85 +NL G D D + A V+ ++ Y G + L Sbjct: 32 INLSIGVCCNDDGDLHIFDSVLNA-DKLVTENYKEKPYLLGNGTEDFS-TLTQNLIFGNN 89 Query: 86 QEIDPLRNV--LVTVGGYGALFTAFQALVDEGDEVIII-EPFFDCYEPMTMMAGGRPVFV 142 + + + + +GG GA+F + L E + + P + + M G ++ Sbjct: 90 SKYIEDKKICTIQCIGGTGAIFVLLEFLKMLNVETLYVTNPPYINHVNMIESRGFNLKYI 149 Query: 143 SLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASL 202 + N+ L +L + + ++ + NP + + + + Sbjct: 150 NF------FDYNLIDINYDLFLNDLRN-IPNGSSVILQISCYNPCSVNIEEKYFDEIIEI 202 Query: 203 CQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTL---TIGSAGKTFSATGWKVGWV 259 V I D YQ + + + + E+ + S K S G + G + Sbjct: 203 VLHKKHVIIFDIAYQGFGHTNLEEDVLL-IRKFEEKNIAFSVCQSFSKNMSLYGERAGAL 261 Query: 260 LG------PDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFPQAM 313 I+ + + P + Q L Q Q + Sbjct: 262 HIVCKNQEEKKIVFNNLCFIVRKFYSSPVIHTNRILCQLLNNQNLKLNWIKELSQLSQRI 321 Query: 314 QRCRDHMIRSLQ 325 R L+ Sbjct: 322 TNNRILFFNKLE 333 >4W91-A nrPDB Length = 422 Score = 61.4 bits (147), Expect = 7e-10, Method: Composition-based stats. Identities = 57/410 (13%), Positives = 124/410 (30%), Gaps = 75/410 (18%) Query: 43 PDFAVEAFQHAVSGDFMLNQYTKTFGYPPLTKILASFFGE-----LLGQEIDPLRNVLVT 97 P ++A HA + ++ G L+ + + + ++ T Sbjct: 52 PQSVIDAVTHAYANEYANVH----RGLHFLSNAATDAYEKSRETVRRFLNAGSVDEIVFT 107 Query: 98 VGGYGALFTA----FQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGE 153 A+ T + EGDE+++ M + P + + Sbjct: 108 KNATEAINTVAYGYGMPFIGEGDEILL--------SIMEHHSNIVPWHFIRERQGAKLVF 159 Query: 154 LGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQQHDVVCITD 213 N E + + RTK + + +N LG V ++ + L + + D Sbjct: 160 TPVDDNGVFHIEEFEKRLSERTKLVAITHMSNTLGTVVP---IKKIVELAHARGIPVLVD 216 Query: 214 EVYQWMVYDGHQHISIASLPGMWERTLTIGSAGKTFSATGWKVGWVLGPDHIMKHLRTVH 273 + H + + L W + + K + +G +G + G +++ +R Sbjct: 217 GSQGAV----HLPVDVQDLGCDW----YVFTGHKVYGPSG--IGVLYGRAQMLEKMR--- 263 Query: 274 QNSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFPQAMQRCRDH--MIRSLQSVGLKP 331 P Q + E E + + P F + + + ++ +G Sbjct: 264 -------PFQGGGEMIEEVTEENVTYNHPPHRFEAGTPPIVQAIGLGAALEYMEKIGRHA 316 Query: 332 IIPQGSYFLITDISDFK----RKMPDLPGAVDEPYDRRFVKWMIK------------NKG 375 I+ + D+ D+ ++ L + P + + ++ G Sbjct: 317 ILAHEA-----DLRDYAHERLGRINSLRIFGNAPDKGAIISFALEGIHAHDVSMVIDRAG 371 Query: 376 LVAIPVSIFYSVPHQKHF--DHYIRFCFV-----KDEATLQAMDEKLRKW 418 + + + P K F R F + L EK RK+ Sbjct: 372 VAVRAGTH-CAQPLLKRFGVTSTCRASFALYNTRAEVDALAEALEKARKF 420 >4LW2-A nrPDB Length = 404 Score = 61.4 bits (147), Expect = 7e-10, Method: Composition-based stats. Identities = 39/236 (16%), Positives = 77/236 (32%), Gaps = 34/236 (14%) Query: 43 PDFAVEAFQHAVS---GDFMLNQYTKTFGYPPLTKILASFFGELLGQEIDPLRNVLVTVG 99 P+ VEA Q S G+ +Q+ + + +LL D ++ T G Sbjct: 35 PEAVVEATQQFYSLSAGNVHRSQFAEAQRLTARYEAAREKVAQLLNAPDDKT--IVWTRG 92 Query: 100 GYGALFTAFQAL----VDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELG 155 ++ Q + GDE+I+ A P + + + +L Sbjct: 93 TTESINMVAQCYARPRLQPGDEIIV--------SVAEHHANLVPWLMVAQQTGAKVVKLP 144 Query: 156 SSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQQHDVVCITDEV 215 ++ D L T R++ L L +N G +L + +V + D Sbjct: 145 LNAQRLPDVDLLPELITPRSRILALGQMSNVTGGC---PDLARAITFAHSAGMVVMVDGA 201 Query: 216 YQWMVYDGHQHISIASLPGMWERTLTIGSAG--KTFSATGWKVGWVLGPDHIMKHL 269 G H + + + + K + TG +G + G +++ + Sbjct: 202 ------QGAVHFP----ADVQQLDIDFYAFSGHKLYGPTG--IGVLYGKSELLEAM 245 >5XT5-A nrPDB Length = 419 Score = 61.4 bits (147), Expect = 8e-10, Method: Composition-based stats. Identities = 49/328 (14%), Positives = 99/328 (30%), Gaps = 61/328 (18%) Query: 23 KLASEHDVVNLGQGFPDFPPPDFAVEAFQHA-------VSGDFMLNQYTKTFGYPPLTKI 75 + + HD+V L P +E V T GY + Sbjct: 18 QQVNGHDLVYLDSAATSQK-PRAVIETLDKYYNQYNSNVHRGVHTLGTRATDGYEGAREK 76 Query: 76 LASFFGELLGQEIDPLRNVLVTVGGYGALFTAF----QALVDEGDEVIIIEPFFD----- 126 + F + ++ T G +L +A + GDEV+I + Sbjct: 77 VRKF------INAKSMAEIIFTKGTTTSLNMVALSYARANLKPGDEVVI---TYMEHHAN 127 Query: 127 --CYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPN 184 ++ G ++ L+ + ++ TS TK + ++ + Sbjct: 128 IIPWQQAVKATGATLKYIPLQEDG------------TISLEDVRETVTSNTKIVAVSHVS 175 Query: 185 NPLGKVFSREELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTIGS 244 N LG V ++ +A + + V + D + + S Sbjct: 176 NVLGTVNP---IKEMAKIAHDNGAVIVVD--------GAQSTPHMKIDVQDLDCDFFALS 224 Query: 245 AGKTFSATGWKVGWVLGPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSS 304 + K TG VG + G +++++ + F + ES +E + + Sbjct: 225 SHKMCGPTG--VGVLYGKKALLENME----PAEFGGEMIDFVGLYESTWKELPWKFEAGT 278 Query: 305 YFVQFPQAMQRCRDHMIRSLQSVGLKPI 332 + + D L+ +GL I Sbjct: 279 PIIAGAIGLGAAIDF----LEEIGLDEI 302 >6ONN-A nrPDB Length = 402 Score = 61.4 bits (147), Expect = 8e-10, Method: Composition-based stats. Identities = 41/251 (16%), Positives = 80/251 (31%), Gaps = 29/251 (11%) Query: 74 KILASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTM 133 L E G +D R + + G Y A AL G + F D ++ Sbjct: 95 AQLEDDLAEFAGGFVDNPRALYFSTG-YMANLATLTALAGRGTTL-----FSDSLNHASL 148 Query: 134 MAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSR 193 + G R ++ P + E + + K +V VFS Sbjct: 149 IDGARLSRADIQIYPHADAEA---------LGAMLEASDAAVKLIV-------SDTVFSM 192 Query: 194 EE----LELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTIGSAGKTF 249 + L + L + H + D+ + + V ++A + +G+ GK Sbjct: 193 DGDIAPLARLLELAEHHGAWLVVDDAHGFGVLGPQGRGAVAEAALRSPHLIVVGTLGKAA 252 Query: 250 SATGWKVGWVLGPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQF 309 +G +V+ + +++ L + +F + AA A S + + Sbjct: 253 GVSG---AFVVAHETVIEWLVQRARPYIFTTASVPSAAHAVSASLRIIGGDEGEHRRAHL 309 Query: 310 PQAMQRCRDHM 320 + RD + Sbjct: 310 RSLIALTRDML 320 >2OGE-A nrPDB Length = 399 Score = 60.6 bits (145), Expect = 1e-09, Method: Composition-based stats. Identities = 44/275 (16%), Positives = 75/275 (27%), Gaps = 41/275 (14%) Query: 70 PPLTKILASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQAL-VDEGDEVIIIEPFFDCY 128 P L A F + + G AL A + L + GDEVI+ + Sbjct: 63 PELEGFEAEFAA------YCETDHAVGVNSGMDALQLALRGLGIGPGDEVIVPSHTYIAS 116 Query: 129 EPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLG 188 G PV V + LDP+ + T RT+AL+ P+ Sbjct: 117 WLAVSATGATPVPVE-----------PHEDHPTLDPLLVEKAITPRTRALL------PVH 159 Query: 189 KVFSREELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTIGSAGKT 248 +++ + L +H + + D G ++ G + GK Sbjct: 160 LYGHPADMDALRELADRHGLHIVEDAAQAH----GARYRGRRIGAGSSVAAFSFY-PGKN 214 Query: 249 FSATGWKVGWVLGPDHIMKHLRTVH--------QNSVFHCPTQSQAAVAESFEREQLLFR 300 G V G + + LR + + ++ A Sbjct: 215 LGCFGDGGAVVTGDPELAERLRMLRNYGSRQKYSHETKGTNSRLDEMQAAVLRIRLAHLD 274 Query: 301 QPSSYFVQFPQAMQRCRDHMIRSLQSVGLKPIIPQ 335 + + L +GL P Sbjct: 275 SWNGRRSALAAEYLSG----LAGLPGIGLPVTAPD 305 >4OC9-A nrPDB Length = 424 Score = 60.2 bits (144), Expect = 2e-09, Method: Composition-based stats. Identities = 43/290 (14%), Positives = 88/290 (30%), Gaps = 46/290 (15%) Query: 65 KTFGYPPLTKILASF----FGELLGQEIDPLRNV--------------LVTVGGYGALFT 106 + + L + A F G + + +P +V + G A F Sbjct: 31 TAYNFENLDQAAARFNLQELGNIYSRLSNPTSDVLGQRLANVEGGAFGIPVASGMAACFY 90 Query: 107 AFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPME 166 A L GD V + + +LK I+ E D Sbjct: 91 ALINLASSGDNVAYSNKIYGG--------TQTLISHTLKNFGIEAREFDID-----DLDS 137 Query: 167 LAGKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQQHDVVCITDEVYQWMVYDGHQH 226 L TKA+ + +NP + ++E + + ++H +V I D Sbjct: 138 LEKVIDQNTKAIFFESLSNPQ---IAIADIEKINQIAKKHKIVSICDNTVA--------- 185 Query: 227 ISIASLPGMWERTLTIGSAGKTFSATGWKVGWVLGPDHIMKHLRTVHQNS-VFHCPTQSQ 285 P + + S K S G +G L + L + F+ P S Sbjct: 186 TPFLLQPFKHGVDVIVHSLSKYVSGQGTALGGALIERKDLNDLLKNNDRYKAFNTPDPSY 245 Query: 286 AAV-AESFEREQLLFRQPSSYFVQFPQAMQ-RCRDHMIRSLQSVGLKPII 333 + + + R ++ ++ + +++ L+++ ++ Sbjct: 246 HGLNLNTLDLPIFSIRVIITWLRDLGASLAPQNAWLLLQGLETLAVRIEK 295 >3UWC-A nrPDB Length = 374 Score = 60.2 bits (144), Expect = 2e-09, Method: Composition-based stats. Identities = 29/139 (20%), Positives = 55/139 (39%), Gaps = 20/139 (14%) Query: 78 SFFGELLGQEIDPLRNVLVTVGGYGALFTAFQAL-VDEGDEVIIIEPFFDCYEPMTMMAG 136 F + + + V G AL +F+ L + GDEVI F + AG Sbjct: 41 EKFEKRFAALHNAPHAIGVGTG-TDALAMSFKMLNIGAGDEVITCANTFIASVGAIVQAG 99 Query: 137 GRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREEL 196 PV V S + + +DP ++ T +TKA++ P+ + ++ Sbjct: 100 ATPVLVD------------SENGYVIDPEKIEAAITDKTKAIM------PVHYTGNIADM 141 Query: 197 ELVASLCQQHDVVCITDEV 215 +A + ++H++ + D Sbjct: 142 PALAKIAKKHNLHIVEDAC 160 >3WGB-A nrPDB Length = 341 Score = 59.4 bits (142), Expect = 3e-09, Method: Composition-based stats. Identities = 44/270 (16%), Positives = 85/270 (31%), Gaps = 28/270 (10%) Query: 41 PPPDFAVEAF-QHAVSGDFMLNQYTKTFGYPPLTKILASFFGELLGQEIDPLRNVLVTVG 99 +A Q + + + Y + G L E G ++ L Sbjct: 12 DTVTQPTDAMRQCMLHAEVGDDVYGEDPGVNAL---------EAYGADLLGKEAALFVPS 62 Query: 100 GYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPV-FVSLKPGPIQNGELGSSS 158 G + A + G+ ++ + G + V+L+P P+Q + + Sbjct: 63 GTMSNLLAVMSHCQRGEGAVLGS---AAHIYRYEAQGSAVLGSVALQPVPMQADGSLALA 119 Query: 159 NWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQQHDVVCITDEV--Y 216 + + FT T+ + L +N GKV L + L +H + D + Sbjct: 120 DVRAAIAPDDVHFTP-TRLVCLENTHN--GKVLPLPYLREMRELVDEHGLQLHLDGARLF 176 Query: 217 QWMVYDGHQHISIASLPGMWERTLTIGSAGKTFSATGWKVG-WVLGPDHIMKHLRTVHQN 275 +V GH ++ L ++ K A VG ++G + R + + Sbjct: 177 NAVVASGH---TVRELVAPFDSVSIC--LSKGLGAP---VGSLLVGSHAFIARARRLRKM 228 Query: 276 SVFHCPTQSQAAVAESFEREQLLFRQPSSY 305 A A F +Q + R + Sbjct: 229 VGGGMRQAGILAQAGLFALQQHVVRLADDH 258 >5JAY-A nrPDB Length = 402 Score = 59.4 bits (142), Expect = 3e-09, Method: Composition-based stats. Identities = 47/297 (15%), Positives = 87/297 (29%), Gaps = 28/297 (9%) Query: 41 PPPDFAVEAFQHAVSGDFMLNQYTKTFGYPPLTKILASFFGELLGQEIDPLRNVLVTVGG 100 P A F N Y +P L +A + G + Sbjct: 35 DTPCAAHMTVDGRAIIGFASNDYLGLAAHPQLIAAIAEG-AQRYGAGSGGSHLLGGHSRA 93 Query: 101 YGALFTAFQALVD---EGDEVIIIEPFFDCYEP---MTMMAGGRPVFVSLKPGPIQNGEL 154 + L V E + + G +L + +G Sbjct: 94 HAQLEDDLAEFVGGFVENARALYFSTGYMANLATLTALAGRGTTLFSDALNHASLIDGAR 153 Query: 155 GSSSNWQL----DPMELAGKF---TSRTKALVLNTPNNPLGKVFSREE----LELVASLC 203 S ++ Q+ D L+ + K +V VFS + L + L Sbjct: 154 LSRADVQIYPHCDTDALSAMLEASDADVKVIV-------SDTVFSMDGDIAPLPRLLELA 206 Query: 204 QQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTIGSAGKTFSATGWKVGWVLGPD 263 +QH I D+ + + V +IA ++IG+ K +G +V + Sbjct: 207 EQHGAWLIVDDAHGFGVLGPQGRGAIAQAALRSPNLISIGTLDKAAGVSG---AFVAAHE 263 Query: 264 HIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFPQAMQRCRDHM 320 +++ L + +F + AA A S + + + Q + R R + Sbjct: 264 TVIEWLVQRARPYIFTTASVPAAAHAVSASLRIIGGEEGDARRAHLQQLIGRTRAML 320 >1E5F-A nrPDB Length = 404 Score = 59.1 bits (141), Expect = 3e-09, Method: Composition-based stats. Identities = 52/355 (14%), Positives = 107/355 (30%), Gaps = 56/355 (15%) Query: 88 IDPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDC----YEPMTMMAGGRPVFVS 143 ++ + T G GA+ ++ GD +I E + C +E G + F++ Sbjct: 74 LEKTEACVATSSGMGAIAATVLTILKAGDHLISDECLYGCTHALFEHALTKFGIQVDFIN 133 Query: 144 LKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASLC 203 P E+ TK + TP NP K+ E + Sbjct: 134 TAI-----------------PGEVKKHMKPNTKIVYFETPANPTLKIIDMERVCK--DAH 174 Query: 204 QQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTIGSAGKTFSA-TGWKVGWVLGP 262 Q V+ I D + + + P + + + SA K + T G + G Sbjct: 175 SQEGVLVIADNTFC---------SPMITNPVDFGVDVVVHSATKYINGHTDVVAGLICGK 225 Query: 263 DHIMKHLRTV-HQNSVFHCPTQSQAAVAES----FEREQLLFRQPSSYFVQFPQAMQRCR 317 +++ +R V ++ + A + + + ++ ++ Sbjct: 226 ADLLQQIRMVGIKDITGSVISPHDAWLITRGLSTLNIRMKAESENAMKVAEYLKSHPAVE 285 Query: 318 DHMIRSLQSV-GLKPIIPQ----GSY--FLITDISDFKRKMPDLPGAVDEPYDRRFVKWM 370 + G Q GS F++ + +K+ D + + + Sbjct: 286 KVYYPGFEDHEGHDIAKKQMRMYGSMITFILKSGFEGAKKLLDNLKLITLAVSLGGCESL 345 Query: 371 IKNKGL---VAIPVSIFYSVPHQKHFDHYIRFCFVKDEATLQAMDEKLRKWKVEL 422 I++ +P D IR ++ DE + +K L Sbjct: 346 IQHPASMTHAVVPKEE---REAAGITDGMIRLSV-----GIEDADELIADFKQGL 392 >1MDZ-A nrPDB Length = 393 Score = 59.1 bits (141), Expect = 4e-09, Method: Composition-based stats. Identities = 28/145 (19%), Positives = 55/145 (37%), Gaps = 23/145 (15%) Query: 74 KILASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQAL-VDEGDEVIIIEPFFDCYEPMT 132 + L + F L G + + + A AL + EGDEVI + M Sbjct: 42 QELEAAFCRLTGNQYA-----VAVSSATAGMHIALMALGIGEGDEVITPSMTWVSTLNMI 96 Query: 133 MMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFS 192 ++ G PV V + + + P + T +TKA++ P+ + Sbjct: 97 VLLGANPVMVDVDRDTLM-----------VTPEHIEAAITPQTKAII------PVHYAGA 139 Query: 193 REELELVASLCQQHDVVCITDEVYQ 217 +L+ + +L +++ + I D + Sbjct: 140 PADLDAIYALGERYGIPVIEDAAHA 164 >6CJB-A nrPDB Length = 391 Score = 56.7 bits (135), Expect = 2e-08, Method: Composition-based stats. Identities = 35/209 (16%), Positives = 74/209 (35%), Gaps = 32/209 (15%) Query: 42 PPDFAVEAFQHAVSGDFMLNQYTKTFGYPPLTKILASFFGELLGQEIDPLRNVLVTVGGY 101 P +A ++ G+ + +Y++T P K + + + + G Sbjct: 34 TPIYATSTYKQIAPGEHLGYEYSRTQN--PTRKA----YEDCIASLESGQKGFAFASG-M 86 Query: 102 GALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQ 161 A+ T L+ GD V+ ++ D Y + V + + + S Sbjct: 87 AAINTVID-LLGSGDHVVAMD---DLYGGTFRLFDK----VKTRTSNLSFSFIDMSV--- 135 Query: 162 LDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQQHDVVCITDEVYQWMVY 221 P + T +TK L L TP+NP + L +A++ ++++++ + D + Sbjct: 136 --PENIEAAITPKTKLLWLETPSNP---MLKLANLRKIAAIAKKYNLITVADNTFA---- 186 Query: 222 DGHQHISIASLPGMWERTLTIGSAGKTFS 250 P + + SA K + Sbjct: 187 -----TPWIQRPLELGFDIVLHSATKYLN 210 >2HOR-A nrPDB Length = 427 Score = 56.4 bits (134), Expect = 3e-08, Method: Composition-based stats. Identities = 34/262 (12%), Positives = 73/262 (27%), Gaps = 47/262 (17%) Query: 71 PLTKILASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQALV--------DEGDEVIIIE 122 L K + E++G R ++ VG + +L +V+ Sbjct: 104 ELEKTIKE-LHEVVGNAAAKDRYIVFGVGVTQLIHGLVISLSPNMTATPDAPESKVVAHA 162 Query: 123 PFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNT 182 PF+ + T + W + ++ + Sbjct: 163 PFYPVFREQTKYFDKKGYV------------------WAGNAANYVNVSNPEQYIEMVTS 204 Query: 183 PNNPLGKVFSREELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTI 242 PNNP G + I D VY W Y ++ + + + + Sbjct: 205 PNNPEG----------LLRHAVIKGCKSIYDMVYYWPHYTPIKYKA--------DEDILL 246 Query: 243 GSAGKTFSATGWKVGWVLGPDH-IMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQ 301 + K +G + GW L D + +L + P ++Q + + + + Sbjct: 247 FTMSKFTGHSGSRFGWALIKDESVYNNLLNYMTKNTEGTPRETQLRSLKVLKEVVAMVKT 306 Query: 302 PSSYFVQFPQA-MQRCRDHMIR 322 ++ R+ + Sbjct: 307 QKGTMRDLNTFGFKKLRERWVN 328 >4L0O-H nrPDB Length = 388 Score = 55.6 bits (132), Expect = 3e-08, Method: Composition-based stats. Identities = 40/222 (18%), Positives = 71/222 (31%), Gaps = 36/222 (16%) Query: 106 TAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPM 165 A +L+ GD V++ + D Y + V L I D Sbjct: 79 HAVFSLLQSGDHVLLGD---DVYGGTFRLFNQVLVKNGLSCTIIDTS----------DIS 125 Query: 166 ELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQQHDVVCITDEVYQWMVYDGHQ 225 ++ TKAL L TP+NPL +L AS+ + H ++ I D + Y Sbjct: 126 QIKKAIKPNTKALYLETPSNPL---LKITDLAQCASVAKDHGLLTIVDNTFATPYYQN-- 180 Query: 226 HISIASLPGMWERTLTIGSAGKTFSATGWKVGWVLGPDHIMKHLRTVHQNSVFHCPTQSQ 285 P + + S K G ++ L T + ++ Q Sbjct: 181 -------PLLLGADIVAHSGTKYLG----------GHSDVVAGLVTTNNEALAQEIAFFQ 223 Query: 286 AAVAESFE-REQLLFRQPSSYFVQFPQAMQRCRDHMIRSLQS 326 A+ ++ L ++ +A Q+ + L+ Sbjct: 224 NAIGGVLGPQDSWLLQRGIKTLGLRMEAHQKNALCVAEFLEK 265 >1CS1-A nrPDB Length = 386 Score = 55.6 bits (132), Expect = 4e-08, Method: Composition-based stats. Identities = 43/285 (15%), Positives = 83/285 (29%), Gaps = 43/285 (15%) Query: 42 PPDFAVEAFQHAVSGDFMLNQYTKTFGYPPLTKILASFFGELLGQEIDPLRNVLVTVGGY 101 PP + + + Y++ G P ++ EL G ++T G Sbjct: 25 PPIHLSSTYNFTGFNEPRAHDYSR-RGNP-TRDVVQRALAELEGGA-----GAVLTNTGM 77 Query: 102 GALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQ 161 A+ + GD +++ P DCY + F SL Sbjct: 78 SAIHLVTTVFLKPGD--LLVAP-HDCYGGSYRL------FDSLAKRGCYRVLFVDQG--- 125 Query: 162 LDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQQHDVVCITDEVYQWMVY 221 D L + K +++ +P+NPL +V + + L ++ V + D + Sbjct: 126 -DEQALRAALAEKPKLVLVESPSNPLLRVVD---IAKICHLAREVGAVSVVDNTF----- 176 Query: 222 DGHQHISIASLPGMWERTLTIGSAGKTFSATGWKVGWVLGPDHIMKHLRTVHQN-SVFHC 280 P L + S K + G ++ + V Sbjct: 177 ----LSPALQNPLALGADLVLHSCTKYLN----------GHSDVVAGVVIAKDPDVVTEL 222 Query: 281 PTQSQAAVAESFEREQLLFRQPSSYFVQFPQAMQRCRDHMIRSLQ 325 + + L + V + QR +++ LQ Sbjct: 223 AWWANNIGVTGGAFDSYLLLRGLRTLVPRMELAQRNAQAIVKYLQ 267 >3BB8-A nrPDB Length = 437 Score = 54.8 bits (130), Expect = 6e-08, Method: Composition-based stats. Identities = 35/152 (23%), Positives = 54/152 (35%), Gaps = 31/152 (20%) Query: 71 PLTKILASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQAL---------VDEGDEVIII 121 GE LG VL T G A A AL + GDEVI + Sbjct: 62 RFNDAFEKKLGEYLGVPY-----VLTTTSGSSANLLALTALTSPKLGVRALKPGDEVITV 116 Query: 122 EPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLN 181 F T+ G PVFV + + ++ + + +TKA+++ Sbjct: 117 AAGFPTTVNPTIQNGLIPVFVDVD-----------IPTYNVNASLIEAAVSDKTKAIMIA 165 Query: 182 TPNNPLGKVFSREELELVASLCQQHDVVCITD 213 LG +F E+ VA ++++ I D Sbjct: 166 HT---LGNLFDLAEVRRVAD---KYNLWLIED 191 >6BLG-A nrPDB Length = 379 Score = 54.8 bits (130), Expect = 7e-08, Method: Composition-based stats. Identities = 34/198 (17%), Positives = 70/198 (35%), Gaps = 34/198 (17%) Query: 40 FPPPDFA---VEAFQHAVSGDFMLNQYTKTFGYPPLTKILASFFGELLGQEIDPLRNVLV 96 F P ++ Q A++ + G T+ + + G L+ Sbjct: 7 FNAPPVVGTELDYMQSAMNSGKLC-------GDGGFTRRCQQWMEQRFGTA-----KALL 54 Query: 97 TVGGYGALFTAFQAL-VDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELG 155 T +L A L + GDEVI+ F ++ G + VFV ++ + Sbjct: 55 TPSCTASLEMAALLLDIQPGDEVIMPSYTFVSTANAFVLRGAKIVFVDIRRDTMN----- 109 Query: 156 SSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQQHDVVCITDEV 215 +D + T +T+A+V P+ E++ + ++ ++++ + D Sbjct: 110 ------IDETLIEAAITDKTRAIV------PVHYAGVACEMDTIMAIADKYNLFVVEDAA 157 Query: 216 YQWM-VYDGHQHISIASL 232 M Y G +I + Sbjct: 158 QGVMSTYKGRALGTIGHI 175 >3QI6-A nrPDB Length = 392 Score = 54.4 bits (129), Expect = 1e-07, Method: Composition-based stats. Identities = 35/229 (15%), Positives = 69/229 (30%), Gaps = 28/229 (12%) Query: 100 GYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSN 159 G A A +A++ GD V+I + D Y + +++ P+ Sbjct: 90 GMAAADCALRAMLRPGDHVVIPD---DAYGGTFRLIDKVFTGWNVEYTPVALA------- 139 Query: 160 WQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQQHDVVCITDEVYQWM 219 D + T+ + + TP NPL S ++ +A L + D + Sbjct: 140 ---DLDAVRAAIRPTTRLIWVETPTNPL---LSIADIAGIAQLGADSSAKVLVDNTFASP 193 Query: 220 VYDGHQHISIASLPGMWERTLTIGSAGKTFSATGWKVGWVLGPDHIMKHLRTVHQNSVFH 279 Q +S+ + + T IG G ++ D + QN Sbjct: 194 AL--QQPLSLGADVVLHSTTKYIGGHSDVVG------GALVTNDEELDQSFAFLQNGAGA 245 Query: 280 CPTQSQAAV----AESFEREQLLFRQPSSYFVQFPQAMQRCRDHMIRSL 324 P A + ++ + ++ +F + L Sbjct: 246 VPGPFDAYLTMRGLKTLVLRMQRHSENAAAVAEFLAEHPAISTVLYPGL 294 >5X5H-A nrPDB Length = 392 Score = 54.0 bits (128), Expect = 1e-07, Method: Composition-based stats. Identities = 49/394 (12%), Positives = 106/394 (26%), Gaps = 56/394 (14%) Query: 32 NLGQG-FPD-----FPPPDFAVEAFQHAVSGDFMLNQYTKTFGYP---PLTKILASFFGE 82 ++ G PD P +A F + G P L + +A+ G Sbjct: 14 SIHAGYEPDDYYGSINTPIYASTTFAQNAPNELRKGYEYTRVGNPTIVALEQTVAALEGA 73 Query: 83 LLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPVFV 142 G+ G A F+ ++ GD +++ D Y + Sbjct: 74 KYGRAFSS---------GMAATDILFRIILKPGDHIVLGN---DAYGGTYRLIDTVFTAW 121 Query: 143 SLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASL 202 ++ + + E+ TK + + TP NP ++E VA L Sbjct: 122 GVEYTVVDTSVV----------EEVKAAIKDNTKLIWVETPTNP---ALGITDIEAVAKL 168 Query: 203 CQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTIGSAGKTFSATGWKVGWVLGP 262 + + + D + Q + + + + T IG G V+ Sbjct: 169 TEGTNAKLVVDNTFASPYL--QQPLKLGAHAVLHSTTKYIGGHSDVVG------GLVVTN 220 Query: 263 D-HIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFPQAMQRCRD--- 318 D + + L + A + + + + + + + Sbjct: 221 DQEMDEELLFMQGGIGPIPSVFDAYLTARGLKTLAVRMDRHCDNAEKIAEFLDSRPEVST 280 Query: 319 HMIRSLQ-----SVGLKPIIPQGSYF--LITDISDFKRKMPDLPGAVDEPYDRRFVKWMI 371 + L+ V K + G + +K + V+ ++ Sbjct: 281 VLYPGLKNHPGHEVAAKQMKRFGGMISVRFAGGEEAAKKFCTSTKLICLAESLGGVESLL 340 Query: 372 KNKGLVAIPVSIFYSVPHQKHFDHYIRFCFVKDE 405 ++ S S +R ++ Sbjct: 341 EHPAT-MTHQSAAGSQLEVPR--DLVRISIGIED 371 >5W70-A nrPDB Length = 445 Score = 53.7 bits (127), Expect = 1e-07, Method: Composition-based stats. Identities = 27/170 (15%), Positives = 58/170 (34%), Gaps = 26/170 (15%) Query: 46 AVEAFQHAVSGDFMLNQYTKTFGYPPLTKILASFFGELLGQEIDPLRNVLVTVGGYGALF 105 +A + + G + A F G + + G +L Sbjct: 49 VPDAVADVLGSGRW-SISGPYRGTESYERRFARAFAAYNGVP-----HCVPAASGTASLM 102 Query: 106 TAFQAL-VDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDP 164 A +A + GDEVI+ + + P+F + P + L P Sbjct: 103 LALEACGIGAGDEVIVPGLSWVASGSTILGVNAVPIFCDVDPDTLC-----------LSP 151 Query: 165 MELAGKFTSRTKALVLNTPNNPLGKVFS-REELELVASLCQQHDVVCITD 213 + T T+A+V+ ++S +++ ++++ ++H + I D Sbjct: 152 EAVEAAITEHTRAIVVV-------HLYSALADMDALSAIAERHGLPLIED 194 >5K8B-A nrPDB Length = 403 Score = 52.9 bits (125), Expect = 3e-07, Method: Composition-based stats. Identities = 30/117 (25%), Positives = 48/117 (41%), Gaps = 19/117 (16%) Query: 100 GYGALFTAFQAL-VDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSS 158 G AL TA A + GDEVI+ F MAG P+F + Sbjct: 61 GTAALQTAMMAAGIGAGDEVIVPPFTFVASVEAIFMAGAVPIFAEIDETLC--------- 111 Query: 159 NWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQQHDVVCITDEV 215 L P + T RTKA+ N + S +++ + ++C++H++V + D Sbjct: 112 ---LSPEGIEAVITPRTKAI------NLVHMCGSMAKMDEIKAICKKHNLVLLEDAC 159 >3AEO-A nrPDB Length = 389 Score = 52.5 bits (124), Expect = 3e-07, Method: Composition-based stats. Identities = 49/336 (14%), Positives = 106/336 (31%), Gaps = 46/336 (13%) Query: 100 GYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSN 159 G GA+ ++ A + +GD +I + + C VSL + + Sbjct: 83 GMGAISSSTLAFLQKGDHLIAGDTLYGC-------------TVSLFTHWLPRFGIEVDLI 129 Query: 160 WQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQQHDVVCITDEVYQWM 219 D ++ + TK + L +P NP KV +++ +A +C + + D Sbjct: 130 DTSDVEKVKAAWKPNTKMVYLESPANPTCKV---SDIKGIAVVCHERGARLVVDA----- 181 Query: 220 VYDGHQHISIASLPGMWERTLTIGSAGKTFSATGWKVGWVLGPDHIMKHLRTVH--QNSV 277 + + L + + S K + G +G + + + T+ + Sbjct: 182 TFTSPCFLKPLELGAD----IALHSVSKYINGHGDVIG-GVSSAKTAEDIATIKFYRKDA 236 Query: 278 FHCPTQSQAAVAES----FEREQLLFRQPSSYFVQFPQAMQRCRDHMIRSLQSV-GLKPI 332 A + + + +F + ++ L+S G Sbjct: 237 GSLMAPMDAFLCARGMKTLPIRMQIHMENGLKVAKFLEQHEKIVKVNHPGLESFPGHDIA 296 Query: 333 IPQ----GSYFLI-TDISDFKRKMPDLPGAVDEPYDRRFVKWMIKNKGL---VAIPVSIF 384 Q GS FL + +K+ + V +I++ A+P +I Sbjct: 297 KKQMTGYGSTFLFEMKSFEAAKKLMEHLKVCTLAVSLGCVDTLIEHPASMTHAAVPENI- 355 Query: 385 YSVPHQKHFDHYIRFCFVKD--EATLQAMDEKLRKW 418 + Q +R + + + + + L W Sbjct: 356 --MRKQGITPELVRISVGIENVDDIIADLKQALELW 389 >3WY7-A nrPDB Length = 404 Score = 52.5 bits (124), Expect = 3e-07, Method: Composition-based stats. Identities = 50/288 (17%), Positives = 92/288 (31%), Gaps = 46/288 (15%) Query: 1 MAKQLQARRLDGIDYN----PWVEFVKLASEHDVVNLGQGFPDFPPPDFAVEAFQHAVSG 56 +A Q RR +G+ P V + +D + L Q PD + + Sbjct: 34 LADIEQRRRAEGLRRELRVRPPVAAELDLASNDYLGLSQ------HPDVLDGGVEALRTW 87 Query: 57 DFMLNQYTKTFGYPPLTKILASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGD 116 G L + LG ++ + G A A AL G Sbjct: 88 GGGAGGSRLVTGNTELHEAFEHQLASFLG----AESALVFSSGYT-ANLGALVALSGPGS 142 Query: 117 EVIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTK 176 ++ ++ R V + + L + + + Sbjct: 143 LIVSDALSHASLVDACRLSRARVVVSPHRDVDAVDAALAARTEE---------------R 187 Query: 177 ALVLNTPNNPLGKVFSREE----LELVASLCQQHDVVCITDEVYQWMVYD--GHQHISIA 230 A+V+ VFS + L + ++C++H + + DE + V G + Sbjct: 188 AVVV------TESVFSADGDLAPLRDLHAVCRRHGALLLVDEAHGLGVRGTRGQGLLHEV 241 Query: 231 SLPGMWERTLTIGSAGKTFSATGWKVGWVLGPDHIMKHLRTVHQNSVF 278 L G + +T + K + G G VLGP+ + HL ++ +F Sbjct: 242 GLAGAPDIVMT-TTLSKALGSQG---GAVLGPEAVRAHLIDTARSFIF 285 >1B9H-A nrPDB Length = 388 Score = 52.1 bits (123), Expect = 4e-07, Method: Composition-based stats. Identities = 35/182 (19%), Positives = 59/182 (32%), Gaps = 25/182 (13%) Query: 38 PDFPPPDFAVEAFQHAVSGDFMLNQYTKTFGYPPLTKILASFFGELLGQEIDPLRNVLVT 97 P+FP +A ++ + Q+ + G + F + VT Sbjct: 7 PEFPAWPQYDDAERNGLVRALEQGQWWRMGGDE------VNSFEREFAAHHGAAHALAVT 60 Query: 98 VGGYGALFTAFQAL-VDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGS 156 G AL A Q + V G EVI+ F G V V + Sbjct: 61 NG-THALELALQVMGVGPGTEVIVPAFTFISSSQAAQRLGAVTVPVDVDAAT-------- 111 Query: 157 SSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQQHDVVCITDEVY 216 + LDP +A T RTK ++ P+ +++ +A + V + D + Sbjct: 112 ---YNLDPEAVAAAVTPRTKVIM------PVHMAGLMADMDALAKISADTGVPLLQDAAH 162 Query: 217 QW 218 Sbjct: 163 AH 164 >1N8P-A nrPDB Length = 393 Score = 52.1 bits (123), Expect = 4e-07, Method: Composition-based stats. Identities = 39/275 (14%), Positives = 86/275 (31%), Gaps = 33/275 (12%) Query: 164 PMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQQH----DVVCITDEVYQWM 219 +L TK + + TP NP KV ++ VA L ++H DV+ + D + Sbjct: 128 LNDLPQLIKENTKLVWIETPTNPTLKVTD---IQKVADLIKKHAAGQDVILVVDNTF--- 181 Query: 220 VYDGHQHISIASLPGMWERTLTIGSAGKTFSA-TGWKVGWVLGPDHIMKHLRTVHQNSVF 278 S P + + + SA K + + +G + + + QN++ Sbjct: 182 ------LSPYISNPLNFGADIVVHSATKYINGHSDVVLGVLATNNKPLYERLQFLQNAIG 235 Query: 279 HCPTQSQAAVAESFEREQLLFRQPSSYFVQFPQAMQRCRDHMIRSLQSVGLKPIIPQ--- 335 P+ A + + L + ++ + ++ GLK Sbjct: 236 AIPSPFDAWLTHRGLKTLHLRVRQAALSANKIAEFLAADKENVVAVNYPGLKTHPNYDVV 295 Query: 336 ---------GSY--FLITDISDFKRKMPDLPGAVDEPYDRRFVKWMIKNKGLVAIPVSIF 384 G F I ++ K ++ +++ ++ Sbjct: 296 LKQHRDALGGGMISFRIKGGAEAASKFASSTRLFTLAESLGGIESLLEVPAVMTHGGIPK 355 Query: 385 YSVPHQKHFDHYIRFC--FVKDEATLQAMDEKLRK 417 + FD +R + L+ + + L++ Sbjct: 356 EAREASGVFDDLVRISVGIEDTDDLLEDIKQALKQ 390 >5IJG-A nrPDB Length = 427 Score = 52.1 bits (123), Expect = 5e-07, Method: Composition-based stats. Identities = 33/240 (13%), Positives = 71/240 (29%), Gaps = 17/240 (7%) Query: 77 ASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAG 136 + + L L + G A+ T A V GD ++ +P + E + Sbjct: 85 SEIVEDRLAVYEGAESAALFSSG-MSAIATTLFAFVRPGDVILHSQPLYGGTETLL---- 139 Query: 137 GRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREEL 196 + F + + ++ R +++ TP NP + + Sbjct: 140 AKTFFNFGVEAVAFADGVHEA---TIEKAAEEALAKGRVSVILIETPANPTNSIVDVAAV 196 Query: 197 ELVAS-LCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTIGSAGKTFSA-TGW 254 VA + + + + D + P L++ S K + Sbjct: 197 RRVAEKIEARQGSRPV-------IACDNTLLGPVFQKPLDHGADLSVYSLTKYVGGHSDL 249 Query: 255 KVGWVLGPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFPQAMQ 314 G VLG +++ ++ + S + S E L + S + ++ Sbjct: 250 IAGAVLGAKSVVRQVKALRGAIGTQLDPHSCWMLGRSLETLGLRMERADSNARAIAEFLR 309 >5TSU-A nrPDB Length = 422 Score = 52.1 bits (123), Expect = 5e-07, Method: Composition-based stats. Identities = 45/259 (17%), Positives = 81/259 (31%), Gaps = 49/259 (18%) Query: 42 PPDFAVEAFQHAVSGDFMLNQYTKTFGYPP---LTKILASFFGELLGQEIDPLRNVLVTV 98 PP F+ G Y+++ G P L K +A+ G VT Sbjct: 56 PPISLSTTFKQGAPGQHSGFNYSRS-GNPTRNCLEKAVAALDGAKYCLAFASGLAATVT- 113 Query: 99 GGYGALFTAFQALVDEGDEVIIIEPFFDC----YEPMTMMAGGRPVFVSLKPGPIQNGEL 154 L+ GD++I ++ + + + G + FV + Sbjct: 114 ---------ITHLLKAGDQIICMDDVYGGTNLYFRQVASEFGLKISFVDCSKIKL----- 159 Query: 155 GSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQQH-DVVCITD 213 L T TK + + TP NP KV +E A + +H D++ + D Sbjct: 160 ------------LEAAITPETKLVWIETPTNPTQKVID---IEGCAHIVHKHGDIILVVD 204 Query: 214 EVYQWMVYDGHQHISIASLPGMWERTLTIGSAGKTFSA-TGWKVGWVLGPDHIMKHLRTV 272 + P +++ SA K + + +G V + + Sbjct: 205 NTFM---------SPYFQRPLALGADISMYSATKYMNGHSDVVMGLVSVNCESLHNRLRF 255 Query: 273 HQNSVFHCPTQSQAAVAES 291 QNS+ P+ + Sbjct: 256 LQNSLGAVPSPIDCYLCNR 274 >5W1B-A nrPDB Length = 467 Score = 51.7 bits (122), Expect = 6e-07, Method: Composition-based stats. Identities = 42/384 (10%), Positives = 100/384 (26%), Gaps = 39/384 (10%) Query: 44 DFAVEAFQHA--VSGDFMLNQYTKTFGYPPLTKILASFFGELLGQEIDPLRNVLVTVGGY 101 D A + Y + Y L F ++ G Sbjct: 51 DSGTNAMSDHQWAAMITGDEAYAGSRNYYDLKDKAKELFNYDY---------IIPAHQGR 101 Query: 102 GALFTAFQALVD-------EGDEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGEL 154 GA F L+ + V I FD + G + + + + Sbjct: 102 GAENILFPVLLKYKQKEGKAKNPVFISNFHFDTTAAHVELNGCKAINIVTEKAFDSETYD 161 Query: 155 GSSSNWQLDP--MELAGKFTSRTKALVLNTPNNPLG-KVFSREELELVASLCQQHDVVCI 211 ++ + +A A+V N G + S L+ V + +QH + + Sbjct: 162 DWKGDFDIKKLKENIAQHGADNIVAIVSTVTCNSAGGQPVSMSNLKEVYEIAKQHGIFVV 221 Query: 212 TDEV-YQWMVYDGHQHISIASLPGMWERTLTIGSAGKTFSATG-----WKVGWVLGPDHI 265 D + Y + E + + + +G ++ Sbjct: 222 MDSARFCENAYFIKARDPKYKNATIKEVIFDMYKYADALTMSAKKDPLLNIGGLVAIRDN 281 Query: 266 MKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFPQAMQRCRDHMIRSLQ 325 + + T+ + + ++ ++ ++ L+ Sbjct: 282 -EEIFTLARQRCVPMEGFVTYGGLAGRDMAAMVQGLEEGTEEEYLHYRIGQVKYLGDRLR 340 Query: 326 SVGLKPIIPQGSYFLITDISDFKRKMPDLPGAVDEPYDRRFVKWMIKNKGLVAIPVSIFY 385 G+ P G + + D ++P D+ + + + G+ A+ + F Sbjct: 341 EAGIPIQYPTGGHAVFVDCKKLVPQIP-----GDQFPAQAVINALYLESGVRAVEIGSFL 395 Query: 386 SVPHQKHFD------HYIRFCFVK 403 + ++R + Sbjct: 396 LGRDPATGEQKHADMEFMRLTIAR 419 >5I92-A nrPDB Length = 435 Score = 51.4 bits (121), Expect = 7e-07, Method: Composition-based stats. Identities = 60/369 (16%), Positives = 114/369 (30%), Gaps = 43/369 (11%) Query: 64 TKTFGYPPLTKILASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQALVDEG----DEVI 119 ++G P L +L+ + + V + G A +A + + G D +I Sbjct: 90 GLSYGAPT---ALEVEMADLVCSMVPSMEMVRMVSSGTEATMSAIR--LARGYTGRDSII 144 Query: 120 IIEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELA------GKFTS 173 E + + ++ G P + L ++ G+ Sbjct: 145 KFEGCYHGHSDSLLVKAGSGALTFGVPNSPGVPAAFAKHTLTLPFNDIEAVRKTLGEVGK 204 Query: 174 RTKALVL--------NTPNNPLGKVFSREELELVASLCQQHDVVCITDEVYQWMVYDGHQ 225 +++ P P LE + C +H VV I DEV Sbjct: 205 EVACIIVEPVAGNMNCVPPAPG-------FLEGLREACDEHGVVLIFDEVMTGF------ 251 Query: 226 HISIASLPGMWERTLTIGSAGKTFSATGWKVGWVLGPDHIMKHLRTVHQNSVFHCPTQSQ 285 +++ + T + + GK G VG G IM+ + + V+ T S Sbjct: 252 RVALGGAQAYYGVTPDLSTFGKIIG-GGMPVGAFGGKREIMQQISPL--GPVYQAGTLSG 308 Query: 286 AAVAESFEREQLLFRQPSSYFVQFPQAMQRCRDHMIRSLQSVGLKPIIPQ-GSYF-LITD 343 +A + L + + R D + + + G+ + Q G F L Sbjct: 309 NPLAMAAGLTTLRLISRPGFHDELTAYTTRMLDGLQQRADAAGIPFVTTQAGGMFGLYFS 368 Query: 344 ISDFKRKMPDLPGAVDEPYDRRFVKWMIKNKGLVAIPVSIFYSVPHQKHFDHYIRFCFVK 403 +D D+ + E + R F ++ + G+ P + H D + Sbjct: 369 GADAIVTFEDVMASDVERFKRFF--HLMLDGGVYLAPSAFEAGFTSIAHGDKELEITLNA 426 Query: 404 DEATLQAMD 412 E A+ Sbjct: 427 AEKAFAALK 435 >4BMK-A nrPDB Length = 442 Score = 51.4 bits (121), Expect = 8e-07, Method: Composition-based stats. Identities = 33/260 (12%), Positives = 79/260 (30%), Gaps = 34/260 (13%) Query: 71 PLTKILASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEP 130 + + L F+G ++ + G Y A L +G+ VI+ Sbjct: 135 EVEQALRDFYGTT--------GAIVFSTG-YMANLGIISTLAGKGEYVILDADSHASIYD 185 Query: 131 MTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKV 190 V + LG K +VL + LG + Sbjct: 186 GCQQGNAEIVRFRHNSVEDLDKRLGRLP-------------KEPAKLVVLEGVYSMLGDI 232 Query: 191 FSREELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTIGSAGKTFS 250 L+ + ++ ++H + + DE + + + + + +G+ + Sbjct: 233 AP---LKEMVAVAKKHGAMVLVDEAHSMGFFGPNGRGVYEAQGLEGQIDFVVGTFSASVG 289 Query: 251 ATGWKVGWVLGPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFP 310 G G+V+ + +R + +F + VA + + L + Sbjct: 290 TVG---GFVVSNHPKFEAVRLACRPYIFTASLP-PSVVATATTSIRKLMTA-----HEKR 340 Query: 311 QAMQRCRDHMIRSLQSVGLK 330 + + + L+++G + Sbjct: 341 ERLWSNARALHGGLKAMGFR 360 >2GMS-A nrPDB Length = 390 Score = 51.0 bits (120), Expect = 1e-06, Method: Composition-based stats. Identities = 24/148 (16%), Positives = 44/148 (29%), Gaps = 31/148 (20%) Query: 78 SFFGELLGQEIDPLRNVLVTVGGYGALFTAFQAL------VDEGDEVIIIEPFFDCYEPM 131 + + V+V+ G L + +GDE+I+ + Sbjct: 37 KQYETQFAKTFGSKYAVMVSSGSTANLLMIAALFFTKKPRLKKGDEIIVPAVSWSTTYYP 96 Query: 132 TMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKAL----VLNTPNNPL 187 G R FV + + +D L T TKA+ +L PNN Sbjct: 97 LQQYGLRVKFVDIDINTLN-----------IDIESLKEAVTDSTKAILTVNLLGNPNN-- 143 Query: 188 GKVFSREELELVASLCQQHDVVCITDEV 215 + + + D++ + D Sbjct: 144 --------FDEINKIIGGRDIILLEDNC 163 >1IBJ-A nrPDB Length = 464 Score = 49.8 bits (117), Expect = 2e-06, Method: Composition-based stats. Identities = 37/233 (15%), Positives = 74/233 (31%), Gaps = 43/233 (18%) Query: 42 PPDFAVEAFQHAVSGDFMLNQYTKTFGYPPLTKILASFFGELLGQEIDPLRNVLVTVGGY 101 P + F+ + + YT++ G P L S +L + R T G Sbjct: 106 TPLYQTATFKQPSAIENGPYDYTRS-GNP-TRDALESLLAKLDKAD----RAFCFTSG-- 157 Query: 102 GALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQ 161 A +A L+ G+E++ + + GG L + + Sbjct: 158 MAALSAVTHLIKNGEEIVAGDDVY----------GGSDR---LLSQVVPRSGVVVKRVNT 204 Query: 162 LDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQQHDVVCITDEVYQWMVY 221 E+A +TK + L +P NP ++ ++ ++ + + + D Sbjct: 205 TKLDEVAAAIGPQTKLVWLESPTNPRQQI---SDIRKISEMAHAQGALVLVD-------- 253 Query: 222 DGHQHISIASLPGMWERTLTIGSAGKTFSATGWKVGWVLGPDHIMKHLRTVHQ 274 + S P + + SA K ++ G +M + V Sbjct: 254 -NSIMSPVLSRPLELGADIVMHSATK----------FIAGHSDVMAGVLAVKG 295 >1FC4-A nrPDB Length = 401 Score = 49.0 bits (115), Expect = 3e-06, Method: Composition-based stats. Identities = 52/380 (13%), Positives = 113/380 (29%), Gaps = 47/380 (12%) Query: 58 FMLNQYTKTFGYPPLTKILASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDE 117 F N Y +P L A + G + +R + T + L A + D Sbjct: 50 FCANNYLGLANHPDLIAA-AKAGMDSHGFGMASVRFICGTQDSHKELEQKLAAFLGMEDA 108 Query: 118 VIIIEPFFDCYEPMTM-MAGGRPVFVSL---KPGPIQNGELGSSSNWQL---DPMELAGK 170 ++ FD + + G +S I L + ++ D EL + Sbjct: 109 ILYSS-CFDANGGLFETLLGAEDAIISDALNHASIIDGVRLCKAKRYRYANNDMQELEAR 167 Query: 171 FTS----RTKALVLNTPNNPLGKVFSRE----ELELVASLCQQHDVVCITDEVYQWMVYD 222 + +++ VFS + L+ V L ++D + + D+ + Sbjct: 168 LKEAREAGARHVLIA-----TDGVFSMDGVIANLKGVCDLADKYDALVMVDDSHAVGFVG 222 Query: 223 GHQHISIASLPGMWERTLTIGSAGKTFSATGWKVGWVLGPDHIMKHLRTVHQNSVFHCPT 282 + S M + G+ GK G G+ +++ LR + +F + Sbjct: 223 ENGRGSHEYCDVMGRVDIITGTLGKALG--GASGGYTAARKEVVEWLRQRSRPYLFS-NS 279 Query: 283 QSQAAVAESFEREQLLFRQPSSYFVQFPQAMQRCRDHMIRSLQSVGLKPIIPQGSYFLIT 342 + A VA S + +++ + + + + G + + Sbjct: 280 LAPAIVAASIKVLEMVEAG-----SELRDRLWANARQFREQMSAAGFTLAGADHAIIPVM 334 Query: 343 DISDFKRKMPDLPGAVDEPYDRRFVKWMIKNKGLVAIPVSIFYSVPHQKHFDHYIRFCFV 402 D ++F + + + +G+ FY V + + Sbjct: 335 --------------LGDAVVAQKFAREL-QKEGIYVT--GFFYPVVPKGQARIRTQMSAA 377 Query: 403 KDEATLQAMDEKLRKWKVEL 422 + E + +L Sbjct: 378 HTPEQITRAVEAFTRIGKQL 397 >5VC2-A nrPDB Length = 424 Score = 49.0 bits (115), Expect = 3e-06, Method: Composition-based stats. Identities = 48/381 (12%), Positives = 102/381 (26%), Gaps = 56/381 (14%) Query: 44 DFAVEAFQHAVSGDFMLNQYT--KTFGYPPLTKILASFFGELLGQEIDPLRNVLVTVGGY 101 +EA ++ + Y + +G + + S E + + + G Sbjct: 46 PSVMEAMGSILTNKY-AEGYPNKRYYGGCEVVDKIESLAIERAKKLFNCQFANVQAHSGS 104 Query: 102 GALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPVF---VSLKPGPIQNGELGSSS 158 A + AL+ D+++ M + GG VSL Q+ G + Sbjct: 105 QANNAVYHALLKPYDKIL----------GMDLSCGGHLTHGAKVSLTGKHYQSFSYGVNL 154 Query: 159 NWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSRE-ELELVASLCQQHDVVCITDEVY- 216 + +D E S +++ + + RE + + + + + + D + Sbjct: 155 DGYIDYEEALKIAQSVKPEIIVCGFS-----AYPREIDFKKFREIADEVGALLLGDIAHV 209 Query: 217 QWMVYDGHQHISIASLPGMWERTLTIGSAGKTFSATGWKVGWVLGPDHIMKHLRTVHQNS 276 +V + + KT + G +L D + Sbjct: 210 AGLVVTNEHAHPFPHCH------VVSSTTHKTLRGP--RGGIILTNDEEIAAKID-KAIF 260 Query: 277 VFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFPQAMQRCRDHMIRSLQSVGLKPIIPQG 336 +A F + + ++ + ++L+ K Sbjct: 261 PGTQGGPLMHVIAAKAVG---FKENLKPEFKAYAKLVKSNMQVLAKALKEKNHKL----- 312 Query: 337 SYFLITDISDFKRKMPDLPGAVDEPYDRRFVKWMIKNKGLVA----IPVSIFYSVPHQKH 392 +S L +D+PY + + N G+ IP Sbjct: 313 -------VSGGTSNHLLLMDFLDKPYSGKDADIALGNAGITVNKNTIPGE-----TRSPF 360 Query: 393 FDHYIRFCFVKDEATLQAMDE 413 IR A E Sbjct: 361 VTSGIRIGSAALSARGMGAKE 381 >3G8M-A nrPDB Length = 417 Score = 48.7 bits (114), Expect = 5e-06, Method: Composition-based stats. Identities = 44/318 (13%), Positives = 91/318 (28%), Gaps = 37/318 (11%) Query: 23 KLASEHDVVNLGQGFPDFPPPDFAV---EAFQHAVSGDFMLNQYTKTFGYPPLTKILA-S 78 + + + + L ++ P + + + +Y Y + + LA Sbjct: 22 EKVRQEEHIEL-IASENYTSPRVMQAQGSQLTNKFAEGYPGKRYYGGCEYVDIVEQLAID 80 Query: 79 FFGELLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGR 138 EL G + NV G A F + AL++ GD V+ + + Sbjct: 81 RAKELFGADYA---NVQPHSGS-QANFAVYTALLEPGDTVLGMNLAHGGHLTHGSPVNFS 136 Query: 139 PVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELEL 198 ++ P I +D +L + +++ + G V + Sbjct: 137 GKLYNIVPYGIDATGH-------IDYADLEKQAKEHKPKMIIGGFSAYSGVV----DWAK 185 Query: 199 VASLCQQHDVVCITDEVY-QWMVYDGHQHISIASLPGMWERTLTIGSAGKTFSATGWKVG 257 + + D + +V G + + T + G + G Sbjct: 186 MREIADSIGAYLFVDMAHVAGLVAAGVYPNPVPHAHVVTTTT--------HKTLAGPRGG 237 Query: 258 WVL---GPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFPQAMQ 314 +L G + + K L NS Q + + L F + Q + Sbjct: 238 LILAKGGSEELYKKL-----NSAVFPGGQGGPLMHVIAGKAVALKEAMEPEFKTYQQQVA 292 Query: 315 RCRDHMIRSLQSVGLKPI 332 + M+ G K + Sbjct: 293 KNAKAMVEVFLERGYKVV 310 >2CTZ-A nrPDB Length = 421 Score = 48.3 bits (113), Expect = 6e-06, Method: Composition-based stats. Identities = 60/420 (14%), Positives = 117/420 (27%), Gaps = 71/420 (16%) Query: 9 RLDGIDYNPWVEFVKLASEHDVVNLGQGFPDFPPPDFA---VEAFQHAVSGDFMLNQYTK 65 R + + + E + L + P +P + E + + N Y++ Sbjct: 2 RFETLQLHAGYE-------PEPTTLSRQVPIYPTTSYVFKSPEHAANLFALKEFGNIYSR 54 Query: 66 TFGYPPLTKILASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFF 125 P +L L G + L T G+ A F A L GD ++ + Sbjct: 55 I--MNPTVDVLEKRLAALEGGKAA-----LATASGHAAQFLALTTLAQAGDNIVSTPNLY 107 Query: 126 DCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNN 185 V+LK I+ P E +T+A + + N Sbjct: 108 GGTFNQFK--------VTLKRLGIEVRFTSREER----PEEFLALTDEKTRAWWVESIGN 155 Query: 186 PLGKVFSREELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTIGSA 245 P + +LE +A ++ V I D + G+ +A W L S Sbjct: 156 P---ALNIPDLEALAQAAREKGVALIVDNTFGM---GGYLLRPLA-----WGAALVTHSL 204 Query: 246 GKTFSATGWKVGWVLGPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSY 305 K WV G ++ N + + L + Sbjct: 205 TK----------WVGGHGAVIAGAIVDGGNFPWEGGRYPLLTEPQPGYHGLRL----TEA 250 Query: 306 FVQFPQAMQRCRDHMIRSLQSVGLKPIIPQGSYFLITDISDFKRKMPDLPGAVDEPYDRR 365 F + ++ D + Q++G P ++ ++ + + Sbjct: 251 FGELAFIVKARVDGLRDQGQALG-----PFEAWVVLLGMETLSLRAERHVENTLHL---- 301 Query: 366 FVKWMIKNKGLVAIPVSIFYSVPHQKHFDHYIR------FCFVKDEATLQAMDEKLRKWK 419 W+++ + + PH Y + F +A + + K Sbjct: 302 -AHWLLEQPQVAWVNYPGLPHHPHHDRAQKYFKGKPGAVLTFGLKGGY-EAAKRFISRLK 359 >2E7J-A nrPDB Length = 371 Score = 47.5 bits (111), Expect = 1e-05, Method: Composition-based stats. Identities = 40/275 (14%), Positives = 96/275 (34%), Gaps = 27/275 (9%) Query: 70 PPLTKILASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYE 129 PP+ + + + LG ++ VT G A F +L + V++ E +C+ Sbjct: 53 PPIHDFIHNQLPKFLGCDVA-----RVTNGAREAKFAVMHSLAKKDAWVVMDE---NCHY 104 Query: 130 PMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGK 189 + A + ++L P + N+ E + + P G Sbjct: 105 SSYVAAERAGLNIALVPKTDYPDYAITPENFAQTIEETKKRGEVVLALITY-----PDGN 159 Query: 190 VFSREELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTIGSAGKTF 249 + +++ +A +C ++DV + + Y G +S+ + + +GS K+ Sbjct: 160 YGNLPDVKKIAKVCSEYDVPLLVNGAYAI----GRMPVSLKEIGADF----IVGSGHKSM 211 Query: 250 SATGWKVGWVLGPDH----IMKHLRTVHQNSV-FHCPTQSQAAVAESFEREQLLFRQPSS 304 +A+G +G + + +++ V T A + + + Sbjct: 212 AASG-PIGVMGMKEEWAEIVLRRSEKYKNKEVELLGCTARGATIITLMASFPHVRERIKR 270 Query: 305 YFVQFPQAMQRCRDHMIRSLQSVGLKPIIPQGSYF 339 + + +A + + ++ +G P +F Sbjct: 271 WDEEVEKARRFAAEMEKLGIKQLGDNPHNHDLMFF 305 >4U1T-A nrPDB Length = 389 Score = 47.5 bits (111), Expect = 1e-05, Method: Composition-based stats. Identities = 40/295 (13%), Positives = 81/295 (27%), Gaps = 47/295 (15%) Query: 34 GQGFPDFPPPDFAVEAFQHAVSGDFMLNQYTKTFGYPPLTKILASFFGELLGQEIDPLRN 93 G D PP ++ + +Y G P + L G E P Sbjct: 18 SAGTGDVVPPIHVSTTYERRAQDEP---RYFYGRGENPTREELEECLA---GLERAPFAT 71 Query: 94 VLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGE 153 V A +LV G V+ + + + + +A + V V G Sbjct: 72 VFS---SGQAAAATLLSLVRPGQCVVSTDDVYAGTDGLFDLAARQGVRVRYADLTTPEGI 128 Query: 154 LGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQQHDVVCITD 213 A + + TP NPL V + V+ + + D Sbjct: 129 A-------------AALAEPDLALVWIETPTNPLLTVVD---VAEVSRRAHERGARVVVD 172 Query: 214 EVYQWMVYDGHQHISIASLPGMWERTLTIGSAGKTFSATGWKVGWVLGPDHIMKHLRTVH 273 + + P +++ S K+ + G ++ V+ Sbjct: 173 NTFA---------SPVLQQPLALGADVSLYSTTKS----------IAGHADVLGGAL-VY 212 Query: 274 QNSVFHCPTQSQAAVAESFER--EQLLFRQPSSYFVQFPQAMQRCRDHMIRSLQS 326 +++ H ++ A + + L R+ ++ L++ Sbjct: 213 RDADLHAAVRAYRTTAGNVPGALDCFLVRRGLHTLSLRVHRQVATARVLVERLRA 267 >4GSA-A nrPDB Length = 432 Score = 47.1 bits (110), Expect = 2e-05, Method: Composition-based stats. Identities = 60/384 (15%), Positives = 113/384 (29%), Gaps = 43/384 (11%) Query: 44 DFAVEAFQHAVSGDFMLNQYTKTFGYPPLTKILASFFGELLGQEIDPLRNVLVTVGGYGA 103 +EA + A+ +FG P L + E++ + + V G A Sbjct: 76 PEVIEALKVAMEK-------GTSFGAPC---ALENVLAEMVNDAVPSIEMVRFVNSGTEA 125 Query: 104 L---FTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNW 160 +A D++I E + + M ++ G V P + +++ Sbjct: 126 CMAVLRLMRAYTGR-DKIIKFEGCYHGHADMFLVKAGSGVATLGLPSSPGVPKKTTANTL 184 Query: 161 QLDPMELAGKFTSRTKALVLNTPNNPLGKVF------------SREELELVASLCQQHDV 208 +L KAL P G + LE + + +HD Sbjct: 185 TTPYNDLEA-----VKALFAENPGEIAGVILEPIVGNSGFIVPDAGFLEGLREITLEHDA 239 Query: 209 VCITDEVYQWMVYDGHQHISIASLPGMWERTLTIGSAGKTFSATGWKVGWVLGPDHIMKH 268 + + DEV I+ + + T + + GK G VG G IM+ Sbjct: 240 LLVFDEVMTGF------RIAYGGVQEKFGVTPDLTTLGKIIG-GGLPVGAYGGKREIMQL 292 Query: 269 LRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFPQAMQRCRDHMIRSLQSVG 328 + ++ T S +A + + L + + Q +R D ++ Q G Sbjct: 293 VAPA--GPMYQAGTLSGNPLAMTAGIKTLELLRQPGTYEYLDQITKRLSDGLLAIAQETG 350 Query: 329 LKPIIPQ-GSYFLITDISDFKRKMPDLPGAVDEPYDRRFVKWMIKNKGLVAIPVSIFYSV 387 Q F D + + + R + +G+ P Sbjct: 351 HAACGGQVSGMFGFFFTEGPVHNYEDAKKSDLQKFSRF--HRGMLEQGIYLAPSQFEAGF 408 Query: 388 PHQKHFDHYIRFCFVKDEATLQAM 411 H + I + A+ Sbjct: 409 TSLAHTEEDIDATLAAARTVMSAL 432 >3GBX-A nrPDB Length = 420 Score = 46.7 bits (109), Expect = 2e-05, Method: Composition-based stats. Identities = 45/285 (15%), Positives = 83/285 (29%), Gaps = 32/285 (11%) Query: 52 HAVSGDFMLNQYTKTFGYPPLTKILASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQAL 111 G Y + ++ EL G + NV G A F + AL Sbjct: 57 KYAEGYPGKRYYGGCEYVDVVEQLAIDRAKELFGADYA---NVQPHSGS-QANFAVYTAL 112 Query: 112 VDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKF 171 + GD V+ + + G PV S K I + S ++D E+A Sbjct: 113 LQPGDTVLGMN-----LAQGGHLTHGSPVNFSGKLYNIVPYGIDESG--KIDYDEMAKLA 165 Query: 172 TSRTKALVLNTPNNPLGKVFSREELELVASLCQQHDVVCITDEVY-QWMVYDGHQHISIA 230 +++ + G V + + + D + ++ G + Sbjct: 166 KEHKPKMIIGGFSAYSGVV----DWAKMREIADSIGAYLFVDMAHVAGLIAAGVYPNPVP 221 Query: 231 SLPGMWERTLTIGSAGKTFSATGWKVGWVL---GPDHIMKHLRTVHQNSVFHCPTQSQAA 287 + T + G + G +L G + + K L NS Q Sbjct: 222 HAHVVTTTT--------HKTLAGPRGGLILAKGGDEELYKKL-----NSAVFPSAQGGPL 268 Query: 288 VAESFEREQLLFRQPSSYFVQFPQAMQRCRDHMIRSLQSVGLKPI 332 + + L F + Q + + M+ + G K + Sbjct: 269 MHVIAGKAVALKEAMEPEFKVYQQQVAKNAKAMVEVFLNRGYKVV 313 >4IYO-A nrPDB Length = 397 Score = 46.7 bits (109), Expect = 2e-05, Method: Composition-based stats. Identities = 47/297 (15%), Positives = 92/297 (30%), Gaps = 54/297 (18%) Query: 42 PPDFAVEAFQHAVSGDFMLNQYTKTFGYPPLTKILASFFGELLGQEIDPLRNVLVTVGGY 101 PP +A + + G+ +Y++T + P F E ++ G Sbjct: 37 PPIYATSTYAQSSPGEHQGFEYSRT--HNPTR-----FAYERCVAALEGGTRAFAFASGM 89 Query: 102 GALFTAFQALVDEGDEVIIIEPFFDCYEPMT-----MMAGGRPVFVSLKPGPIQNGELGS 156 A T + L+D G V+ ++ + + AG FV L Sbjct: 90 AATSTVME-LLDAGSHVVAMDDLYGGTFRLFERVRRRTAGLDFSFVDLT----------- 137 Query: 157 SSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQQHDVVCITDEVY 216 DP + TK + + TP NP + ++ +A + ++H ++ + D + Sbjct: 138 ------DPAAFKAAIRADTKMVWIETPTNP---MLKLVDIAAIAVIARKHGLLTVVDNTF 188 Query: 217 QWMVYDGHQHISIASLPGMWERTLTIGSAGKTFS----ATGWKVGW-VLGPDHIMKHLRT 271 + P L + SA K + G G V+G + + Sbjct: 189 A---------SPMLQRPLSLGADLVVHSATKYLNGHSDMVG---GIAVVGDNAELAEQMA 236 Query: 272 VHQNSVFHCPTQSQAAVAES----FEREQLLFRQPSSYFVQFPQAMQRCRDHMIRSL 324 QNS+ + +A + + Q+ + + L Sbjct: 237 FLQNSIGGVQGPFDSFLALRGLKTLPLRMRAHCENALALAQWLETHPAIEKVIYPGL 293 >4ADC-A nrPDB Length = 406 Score = 46.7 bits (109), Expect = 2e-05, Method: Composition-based stats. Identities = 48/285 (16%), Positives = 91/285 (31%), Gaps = 45/285 (15%) Query: 69 YPPLTKIL----ASFFGELLGQEIDP-------------LRNVLVTVGGYGALFTAFQAL 111 +P L + L + F+ G +P V G A A + Sbjct: 57 HPELREALNEQASKFWHTGNGYTNEPVLRLAKKLIDATFADRVFFCNSGAEANEAALKLA 116 Query: 112 VD-EGDE-------VIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLD 163 D ++ + F T+ AGG+P S P+ ++ N D Sbjct: 117 RKFAHDRYGSHKSGIVAFKNAFHGRTLFTVSAGGQPA-YSQDFAPLPADIRHAAYN---D 172 Query: 164 PMELAGKFTSRTKALVLNTPNNPLGKV-FSREELELVASLCQQHDVVCITDEVYQWMVYD 222 + T A+++ G V S L+ + LC +H+ + I DEV + Sbjct: 173 INSASALIDDSTCAVIVEPIQGEGGVVPASNAFLQGLRELCNRHNALLIFDEVQTGVGRT 232 Query: 223 GHQHISIASLPGMWERTLTIGSAGKTFSATGWKVGWVLGPDHIMKHLRTVHQNSVFHCPT 282 G + + + T + + K G+ VG +L + + TV + + Sbjct: 233 GELYAYM-----HYGVTPDLLTTAKALG-GGFPVGALLATEEC-ARVMTVGTHGTTYGGN 285 Query: 283 QSQAAVAESFEREQLLFRQPSSYFVQFPQAMQRCRDHMIRSLQSV 327 +AVA + +++ D + L ++ Sbjct: 286 PLASAVAGKVLELINT--------PEMLNGVKQRHDWFVERLNTI 322 >5VPR-A nrPDB Length = 414 Score = 46.3 bits (108), Expect = 2e-05, Method: Composition-based stats. Identities = 49/349 (14%), Positives = 100/349 (28%), Gaps = 62/349 (17%) Query: 15 YNPWVEFVKLASEHDVVNLGQGFPDFPPPDFAVEAFQHAVSGDFMLNQYTKT--FGYPPL 72 + + + + D+V L P ++A + Y G L Sbjct: 16 RSQFPILQEKVNGKDLVYLDNAATSQK-PKMVLDAINNYYE------HYNANVHRGIHTL 68 Query: 73 TKILASFFGELLG-----QEIDPLRNVLVTVGGYGALFT---AFQALVDEGDEVIIIEPF 124 +++ + VL T G + A L+ + DE+II Sbjct: 69 SQVATEMMEDARKKVQRFINAKHDYEVLFTKGTTEGINLVAYAMTDLIKKDDEIII---- 124 Query: 125 FDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPN 184 Y + P + + + + + + L L + +TK + +N + Sbjct: 125 --SYLE--HHSNIVPWQMLCQRTGAKLRVIPMNEDGTLQIDVLDEWLSEKTKLVSVNQVS 180 Query: 185 NPLGKVFSREELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTIGS 244 N LG V +E+ + + + + D H I + + Sbjct: 181 NALGIVNPIDEI--IRKVRAKSNAFIFIDGA------QAAPHFEI----DVQTMDCDFFA 228 Query: 245 AG--KTFSATGWKVGWVLGPDHIMKHLRTVHQ------------------NSVFHCPTQS 284 K + TG G + G +++ L H F T + Sbjct: 229 FSGHKMYGPTG--TGILYGKASVLEQLNPFHGGGEMIDHCTFEKTTYAGLPFRFEAGTPN 286 Query: 285 QA---AVAESFEREQLLFRQPSSYFVQFPQAMQRCRDHMIRSLQSVGLK 330 A A+ + + + + R + + + I L+ G K Sbjct: 287 IAGNIAIGTAVDFMEKVGRSNIAAHEHALLEYAQRKLLEIEGLKVYGEK 335 >2CB1-A nrPDB Length = 412 Score = 46.0 bits (107), Expect = 3e-05, Method: Composition-based stats. Identities = 44/235 (18%), Positives = 77/235 (32%), Gaps = 38/235 (16%) Query: 34 GQGFPDFPPPDFAVEAFQHAVSGDFMLNQYTKTFGYPPLTKILASFFGELLGQEIDPLRN 93 G P + + + + Y P K L L G L Sbjct: 19 AVGLPIYAVAAYGFKTLEEGQERFATGEGYVYARQKDPTAKALEERLKALEG----ALEA 74 Query: 94 VLVTVGGYGALFTAFQALVDEGDEVIIIEPFFD----CYEPMTMMAGGRPVFVSLKPGPI 149 V++ G A F A AL+ GDEV+ + F + + + G +V Sbjct: 75 VVLASG-QAATFAALLALLRPGDEVVAAKGLFGQTIGLFGQVLSLMGVTVRYVD------ 127 Query: 150 QNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQQHDVV 209 +P + +++T+A+ + T NP V +LE +A+L ++ V Sbjct: 128 ------------PEPEAVREALSAKTRAVFVETVANPALLV---PDLEALATLAEEAGVA 172 Query: 210 CITDEVYQWMVYDGHQHISIASLPGMWERTLTIGSAGKTFSATGWKVGWVLGPDH 264 + D + G +A W + + S K S G +G + Sbjct: 173 LVVDNTFGA---AGALCRPLA-----WGAHVVVESLTKWASGHGSVLGGAVLSRE 219 >4P3M-A nrPDB Length = 429 Score = 44.8 bits (104), Expect = 8e-05, Method: Composition-based stats. Identities = 43/292 (14%), Positives = 82/292 (28%), Gaps = 40/292 (13%) Query: 54 VSGDFMLNQYTKTFGYPPLT-----------KILA-SFFGELLGQEIDPLRNVLVTVGGY 101 G + N+Y GYP + LA L G + NV G Sbjct: 46 AQGSQLTNKY--AEGYPGKRYYGGCEYVDVAESLAIERAKSLFGADYA---NVQPHSGS- 99 Query: 102 GALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQ 161 A +QAL GD ++ + G V S K + + Sbjct: 100 QANAAVYQALCAPGDTILG-----MSLAHGGHLTHGSHVSFSGKMYNAVQYGITPETG-I 153 Query: 162 LDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQQHDVVCITDEVY-QWMV 220 LD E+ +++ + G V + + + D + +V Sbjct: 154 LDYAEIERLAVEHKPTMIIAGFSAYSGIV----DWAKFREIADKVGAYLFVDMAHVAGLV 209 Query: 221 YDGHQHISIASLPGMWERTLTIGSAGKTFSATGWKVGWVLGPDHIMKHLRTVHQNSVFHC 280 G + + + KT + G +L + + + ++VF Sbjct: 210 AAGLYPNPVPFAD------VVTTTTHKTLGGP--RGGLILAKAN--EAIEKKLNSAVFPG 259 Query: 281 PTQSQAAVAESFEREQLLFRQPSSYFVQFPQAMQRCRDHMIRSLQSVGLKPI 332 + + + V + Q + M++S + G K + Sbjct: 260 QQGGPLMHVIAAKAVAFKECAEPEFAV-YQQQVLDNAKAMVKSFLARGYKIV 310 >2DR1-A nrPDB Length = 386 Score = 44.0 bits (102), Expect = 1e-04, Method: Composition-based stats. Identities = 39/268 (14%), Positives = 86/268 (32%), Gaps = 41/268 (15%) Query: 86 QEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVII-IEPFFDC-YEPMTMMAGGRPVFVS 143 E++ +LV G G + + + V +G +V++ I F Y+ + G + V + Sbjct: 66 LEVEKGEVLLVPSSGTGIMEASIRNGVSKGGKVLVTIIGAFGKRYKEVVESNGRKAVVLE 125 Query: 144 LKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGK-VFSREELELVASL 202 +PG + + ++ A + +A+ + N V + L +A + Sbjct: 126 YEPGKAV----------KPEDLDDALRKNPDVEAVTITY--NETSTGVLNP--LPELAKV 171 Query: 203 CQQHDVVCITDEVY----QWMVYDGHQHISIASLPGMW---ERTLTIGSAGKTF-----S 250 ++HD + D V + +D + S L IG+ + F Sbjct: 172 AKEHDKLVFVDAVSAMGGADIKFDKWGLDVVFSSSQKAFGVPPGLAIGAFSERFLEIAEK 231 Query: 251 AT--GWKVGWVLGPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQ 308 GW + +++ P Q R + Sbjct: 232 MPERGW-----YFDIPLYVKYLKEKESTPSTPPMP-QVFGINVALRIIEKMGGKEKWL-- 283 Query: 309 FPQAMQRCRDHMIRSLQSVGLKPIIPQG 336 + ++ + ++ +GL + G Sbjct: 284 --EMYEKRAKMVREGVREIGLDILAEPG 309 >3NDN-A nrPDB Length = 414 Score = 43.6 bits (101), Expect = 1e-04, Method: Composition-based stats. Identities = 32/225 (14%), Positives = 71/225 (31%), Gaps = 35/225 (15%) Query: 95 LVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGEL 154 T G A+FT+ AL+ GD + R +F S + Sbjct: 100 FATASGMAAVFTSLGALLGAGD----------------RLVAARSLFGSCFVVCSEILPR 143 Query: 155 GSSSNWQLDPMEL---AGKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQQHDVVCI 211 +D +L + T+A+ TP+NP+ + + V L + Sbjct: 144 WGVQTVFVDGDDLSQWERALSVPTQAVFFETPSNPMQSLVD---IAAVTELAHAAGAKVV 200 Query: 212 TDEVYQWMVYDGHQHISIASLPGMWERTLTIGSAGKTFSATGWKV--GWVLGPDHIMKH- 268 D V+ + + + S K G +V G +LG + Sbjct: 201 LDNVFA---------TPLLQQGFPLGVDVVVYSGTKHIDGQG-RVLGGAILGDREYIDGP 250 Query: 269 LRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFPQAM 313 ++ + +++ + + + E + + ++ + + + Sbjct: 251 VQKLMRHTGPAMSAFNAWVLLKGLETLAIRVQHSNASAQRIAEFL 295 >5VMB-A nrPDB Length = 425 Score = 43.3 bits (100), Expect = 2e-04, Method: Composition-based stats. Identities = 39/284 (13%), Positives = 80/284 (28%), Gaps = 30/284 (10%) Query: 52 HAVSGDFMLNQYTKTFGYPPLTKILASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQAL 111 G Y + ++ EL G + NV G A + AL Sbjct: 61 KYAEGYPGKRYYGGCEFVDVIEQMAIDRAKELFGADYA---NVQPHAGS-QANSAVYLAL 116 Query: 112 VDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKF 171 ++ GD V+ + G + F +Q G + ++D E+ Sbjct: 117 LNPGDTVL----GMSLAHGGHLTHGAKVSFSGKTYNAVQYGLNAETG--EIDYEEVERLA 170 Query: 172 TSRTKALVLNTPNNPLGKVFSREELELVASLCQQHDVVCITDEVY-QWMVYDGHQHISIA 230 +++ + +V + +A + D + +V G + Sbjct: 171 LEHKPRMIVAGFSA-YSRVVDWQRFRDIAD---KVGAYLFVDMAHVAGLVAAGVYPNPVQ 226 Query: 231 SLPGMWERTLTIGSAGKTFSATGWKVGWVL--GPDHIMKHLRTVHQNSVFHCPTQSQAAV 288 +T + KT + G +L + I K L++ + A+ Sbjct: 227 IAD------VTTTTTHKTLRGP--RSGLILAKANEEIEKKLQSA--VFPGNQGGPLMHAI 276 Query: 289 AESFEREQLLFRQPSSYFVQFPQAMQRCRDHMIRSLQSVGLKPI 332 A + F + Q + + M + G + Sbjct: 277 AAKAICFKEAMSDD---FKAYQQQVVKNAQAMAEVFIARGYDVV 317 >4JF0-A nrPDB Length = 422 Score = 42.9 bits (99), Expect = 3e-04, Method: Composition-based stats. Identities = 60/383 (15%), Positives = 111/383 (28%), Gaps = 54/383 (14%) Query: 44 DFAVEAFQHAVSGDFMLNQYTKTFGYPPLTKILASFFGELLGQEIDPLRNVLVTVGGYGA 103 VEA + + ++ P L G L + VL G A Sbjct: 76 PALVEALKSQGETLWHTSRVFTNE--PALR------LGRKL-IDATFAERVLFMNSGTEA 126 Query: 104 LFTAFQALVDEGDEVIIIEPFFDCYEPMT-MMAGGRPVFVSLKPGPIQNGELGSSSNWQL 162 TAF+ + + PF G VS+ P + G + Sbjct: 127 NETAFK--LARHYACVRHSPFKTKIIAFHNAFHGRSLFTVSVGGQPKYSDGFGPKPADII 184 Query: 163 -----DPMELAGKFTSRTKALVLNTPNNPLGK-VFSREELELVASLCQQHDVVCITDEVY 216 D + T A+V+ G + E L+ + LC +H + + DEV Sbjct: 185 HVPFNDLHAVKAVMDDHTCAVVVEPIQGEGGVQAATPEFLKGLRDLCDEHQALLVFDEVQ 244 Query: 217 QWMVYDGHQHISIASLPGMWERTLTIGSAGKTFSATGWKVGWVLGPDHIMKHLRTVHQNS 276 M G + + T I ++ K G+ V +L I S Sbjct: 245 CGMGRTGDLFAYM-----HYGVTPDILTSAKALG-GGFPVSAMLTTQEIASAFHVGSHGS 298 Query: 277 VFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFPQAMQRCRDHMIRSLQSVGLKPIIPQG 336 + + A +F+ + Q + R ++ LQ++ Sbjct: 299 TYGGNPLACAVAGATFDIINT---------PEVLQGIHTKRQQFVQHLQAI-------DE 342 Query: 337 SYFLITDISDFKRKMPDLPGAVDEPYDRRFVKWMIKNKGLVAIPVSIFYSVPHQKHFDHY 396 + + +DI + + R F + G++ + Sbjct: 343 QFDIFSDIRGMGLLIGAELKPKYKGRARDF-LYAGAEAGVMVLNA-----------GADV 390 Query: 397 IRF--CFVKDEATLQAMDEKLRK 417 +RF V +EA + ++ + Sbjct: 391 MRFAPSLVVEEADIHEGMQRFAQ 413 >6FYQ-A nrPDB Length = 484 Score = 42.5 bits (98), Expect = 4e-04, Method: Composition-based stats. Identities = 39/299 (13%), Positives = 92/299 (30%), Gaps = 30/299 (10%) Query: 46 AVEAFQHAVSGDFMLNQYTKTFGYPPLTKILASFFGELLGQEIDPLRNVLVTVGGYGALF 105 EA + + ++ P + ++ + L V T GG + Sbjct: 102 LAEAAAQQMKKMAFSSAFSTFSHEPAIRLA-----EKIASITPEGLNAVFFTSGGSESND 156 Query: 106 TAFQALV-------DEGD-EVIIIEPFFDCYEPMTMMAGGRPVF------VSLKPGPIQN 151 +A + + ++I ++ + + G P F + + Sbjct: 157 SAVKLVRHYWKIQGKPNKRKIISLKRSYHGVAAASTSVTGIPEFWGMAGHMMTDFLHVDT 216 Query: 152 GELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVF--SREELELVASLCQQHDVV 209 ++ + + T A P G V + + +C + ++ Sbjct: 217 HYNNTTEQAVQSLCQAIEEAGPETIAAFFAEPVQGAGGVIIPPEDYFLRIREVCNAYGIL 276 Query: 210 CITDEVYQWMVYDGHQHISIASLPGMWERTLTIGSAGKTFSATGWKVGWVLGPDHIMKHL 269 + DEV G W+ + + K ++ + +G V+ D I + L Sbjct: 277 FVADEVITGFGRTGKMFGI-----ENWDVIPDVMTFAKGVTSGYFPLGGVVVSDPIHEVL 331 Query: 270 RTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFPQAMQRCRDHMIRSLQSVG 328 + ++FH T S A + + + + + + +R D ++ L+ V Sbjct: 332 KEKSVGTLFHGFTYSGHPTAAAVALKNIAIIKE----ERLVENSKRMGDALLHGLKKVK 386 >3N0L-A nrPDB Length = 417 Score = 42.1 bits (97), Expect = 5e-04, Method: Composition-based stats. Identities = 38/338 (11%), Positives = 103/338 (30%), Gaps = 35/338 (10%) Query: 6 QARRLDGIDYNPW-VEFVKLASEHDVVNLGQGFPDFPPPDFAVEAFQHAVSGDFMLNQYT 64 A L+ D + + +L + + + + +F P+ E ++ + Y Sbjct: 2 NAMSLEMFDKEIFDLTNKELERQCEGLEM-IASENFTLPEVM-EVMGSILTNKY-AEGYP 58 Query: 65 --KTFGYPPLTKILASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIE 122 + +G + + E + + + G A + AL++ GD+++ ++ Sbjct: 59 GKRYYGGCEFVDEIETLAIERCKKLFNCKFANVQPNSGSQANQGVYAALINPGDKILGMD 118 Query: 123 PFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAG-KFTSRTKALVLN 181 + G + VS ++ G + ++D ++ + K +V Sbjct: 119 LSHGGHLT----HGAK---VSSSGKMYESCFYGVELDGRIDYEKVREIAKKEKPKLIVC- 170 Query: 182 TPNNPLGKVFSRE-ELELVASLCQQHDVVCITDEVY-QWMVYDGHQHISIASLPGMWERT 239 ++R + + + D + +V G Sbjct: 171 -----GASAYARVIDFAKFREIADEIGAYLFADIAHIAGLVVAGEHPSPFPYAH------ 219 Query: 240 LTIGSAGKTFSATGWKVGWVLGPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLF 299 + + KT + G ++ D L +++F + + F Sbjct: 220 VVSSTTHKTLRGP--RGGIIMTNDE---ELAKKINSAIFPGIQGGPLMHVIAAKAVGFKF 274 Query: 300 RQPSSYFVQFPQAMQRCRDHMIRSLQSVGLKPIIPQGS 337 + V + + ++ + L K ++ G+ Sbjct: 275 NLSDEWKV-YAKQVRTNAQVLANVLMDRKFK-LVSDGT 310 >4J5U-A nrPDB Length = 420 Score = 41.3 bits (95), Expect = 8e-04, Method: Composition-based stats. Identities = 47/319 (14%), Positives = 89/319 (27%), Gaps = 38/319 (11%) Query: 23 KLASEHDVVNLGQGFPDFPPPDFAVEAFQHAVSGDFMLNQYTKTF---GYPPLTKILASF 79 + + V+ L +F P +EA Q A+ + Y G + K Sbjct: 22 EKLRQSSVIEL-IASENFVSP-AVLEA-QGALLTNKYAEGYPSKRFYNGCEEVDKAENLA 78 Query: 80 FGELLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVI---IIEPFFDCYEPMTMMAG 136 + NV G A + AL+ GD V+ + + M+G Sbjct: 79 IERVKKLFNCKYANVQPHSGS-QANQAVYLALLQPGDTVLGMSLDSGGHLTHGAAPNMSG 137 Query: 137 GRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSRE-E 195 VS + + +D E+ L++ + + R + Sbjct: 138 KWFNAVS---------YSVNKETYLIDYDEIERLADLHKPKLLIAGFS-----AYPRNID 183 Query: 196 LELVASLCQQHDVVCITDEVY-QWMVYDGHQHISIASLPGMWERTLTIGSAGKTFSATGW 254 + + + D + +V G I + +T + KT Sbjct: 184 FAKFREIVDKVGAYFMADIAHIAGLVATGEHQSPIP-----YAHAVT-STTHKTLRGP-- 235 Query: 255 KVGWVLGPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFPQAMQ 314 + G +L D + H NS Q + + + + Q + Sbjct: 236 RGGLILSNDEEIGH----KINSALFPGLQGGPLMHIIAAKAVAFLENLQPEYKSYIQQVI 291 Query: 315 RCRDHMIRSLQSVGLKPII 333 + SLQ G + Sbjct: 292 SNAKALASSLQERGYDILT 310 >1SVV-A nrPDB Length = 359 Score = 41.3 bits (95), Expect = 9e-04, Method: Composition-based stats. Identities = 51/335 (15%), Positives = 100/335 (29%), Gaps = 49/335 (14%) Query: 89 DPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCY--EPMTMMAGGRPVFVSLKP 146 P +V GG A + + VI + G + V Sbjct: 64 RPDADVHFISGGTQTNLIACSLALRPWEAVIATQLGHISTHETGAIEATGHKVVTAPCPD 123 Query: 147 GPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQQH 206 G ++ ++ S+ L K + ++ +G ++++ELE +++ C++H Sbjct: 124 GKLRVADIESA----LHENRSEHMVIP--KLVYISNTTE-VGTQYTKQELEDISASCKEH 176 Query: 207 DVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTIGSAGKTFSATGWKVGWVLGPDHIM 266 + D G + S S P I F K G + G I+ Sbjct: 177 GLYLFLD---------GARLASALSSPVNDLTLADIARLTDMFYIGATKAGGMFGEALII 227 Query: 267 KHLRTVHQNSVFHCPTQSQAAVAESFERE-QLLFRQPSSYFVQFPQAMQRCRDHMIRSLQ 325 L + + H Q A +A+ + Q + F + + + L+ Sbjct: 228 --LNDALKPNARHLIKQRGALMAKGWLLGIQFEVLMKDNLFFELGAHSNKMAAILKAGLE 285 Query: 326 SVGLKPIIPQGSYFLITDISDFKRKMPDLPGAVDEPYDRRFVKWMIKNKGLVAIPVSIFY 385 + G++ P S L + + + D Y Sbjct: 286 ACGIRLAWPSASNQLFP--------ILENTMIAELNNDFDM------------------Y 319 Query: 386 SVPHQKHFDHYIRFC--FVKDEATLQAMDEKLRKW 418 +V K +R C + +E E L++ Sbjct: 320 TVEPLKDGTCIMRLCTSWATEEKECHRFVEVLKRL 354 >4QGR-A nrPDB Length = 382 Score = 41.0 bits (94), Expect = 0.001, Method: Composition-based stats. Identities = 26/173 (15%), Positives = 47/173 (27%), Gaps = 24/173 (13%) Query: 46 AVEAFQHAVSGDFMLNQYTKTFGYPPLTKILASFFGELLGQEIDPLRNVLVTVGGYGALF 105 A+S +Y K L + G + +V+ G AL Sbjct: 21 IENRLNAAISKVVAEGRYILGPEVAEFEKKLGEYLG---------VEHVIACANGTDALQ 71 Query: 106 TAFQAL-VDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNG--ELGSSSNWQL 162 + G V + F + + G PVFV + P +L ++ + Sbjct: 72 MPLMTRGIGPGHAVFVPSFTFAATAEVVALVGAEPVFVDVDPDSYNMNVEQLEAAIAATI 131 Query: 163 DPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQQHDVVCITDEV 215 L K L N + ++ ++ + I D Sbjct: 132 KEGRLEPKAIIPVDLFGLAASYN------------RITAIAEREGLFIIEDAA 172 >4PPM-A nrPDB Length = 861 Score = 41.0 bits (94), Expect = 0.001, Method: Composition-based stats. Identities = 47/307 (15%), Positives = 89/307 (28%), Gaps = 35/307 (11%) Query: 21 FVKLASEHDVVNLGQGFPDFPPPDFAVEAFQHAV-SGDFMLNQYTKTFGYPPLTKILASF 79 F+ + + + +NLG P V A ++ + + QY P T LA Sbjct: 435 FLDMVAGYGCLNLG------HNPQPVVNALKNYLDAQGPNFIQY---ISIPEQTAKLAEV 485 Query: 80 FGELLGQEIDPLRNVLVTVGGYGALFTAFQ----ALVDEGDEVIIIEPFFDC-YEPMTMM 134 L + V + G A+ A + + G + + + + Sbjct: 486 LCRLAPGNM---GRVFFSNSGTEAVEAAMKIAKASTGKPG--IAYLRNSYHGKTLGALSI 540 Query: 135 AGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVF--S 192 G P E+ D L ++ P G V Sbjct: 541 TGRDKHRRYFTPLLDAMVEVPFG-----DLAALREALNREDVGALMIEPIQGEGGVHIPP 595 Query: 193 REELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTIGSAGKTFSAT 252 L+ V LC++ V+ + DEV + G G+ L + K+ S Sbjct: 596 AGYLQAVQQLCRETGVLLMVDEVQTGLGRTGKLFA--CEWDGIEPDVLML---SKSLSGG 650 Query: 253 GWKVGWVLGPDHIMKHLRTVHQNSVFHCPTQSQ---AAVAESFEREQLLFRQPSSYFVQF 309 +G L + + + H T A+V ++L + + + Sbjct: 651 LIPIGATLCRADLWQKAYGTADRFLVHSSTYGGGNLASVVALSALREILAQDLVGHAERM 710 Query: 310 PQAMQRC 316 ++ Sbjct: 711 GAYFKQA 717 >3ISL-A nrPDB Length = 416 Score = 40.6 bits (93), Expect = 0.001, Method: Composition-based stats. Identities = 40/285 (14%), Positives = 86/285 (30%), Gaps = 41/285 (14%) Query: 64 TKTFG--YPPLTKILASFFGELLGQEIDPLRNVLVTVG-GYGALFTAFQALVDEGDEVII 120 T G P T I+ L R G + ++++ D+V+I Sbjct: 32 TPVVGQFDPAFTGIMNETMEMLRELFQTKNRWAYPIDGTSRAGIEAVLASVIEPEDDVLI 91 Query: 121 IEPFFDCY----EPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTS-RT 175 P + + + G + + G + DP ++ + + Sbjct: 92 --PIYGRFGYLLTEIAERYGANVHMLECEWGTV------------FDPEDIIREIKKVKP 137 Query: 176 KALVLNTPNNPLGKVFSREELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGM 235 K + + G++ L+ + C+ D + I D V + G + + Sbjct: 138 KIVAMVHGETSTGRIHP---LKAIGEACRTEDALFIVDAV-ATI---GGCEVKV----DE 186 Query: 236 WERTLTIGSAGKTFSATGWKVGWV-LGPDHIMKHLRTVHQNSVFHCPTQSQAAVAE---S 291 W+ IG K S G + + + + + TQ+ A Sbjct: 187 WKIDAAIGGTQKCLSVP---SGMAPITYNERVADVIAARKKVERGIATQADRAALSGNRP 243 Query: 292 FEREQLLFRQPSSYFVQFPQAMQRCRDHMIRSLQSVGLKPIIPQG 336 Q Y+ + M+ +L+ G++ ++ +G Sbjct: 244 ITSNYFDLSQLEDYWSERRLNHHTEATTMLYALRE-GVRLVLEEG 287 >3RUY-A nrPDB Length = 392 Score = 40.6 bits (93), Expect = 0.001, Method: Composition-based stats. Identities = 27/173 (15%), Positives = 52/173 (30%), Gaps = 10/173 (5%) Query: 163 DPMELAGKFTSRTKALVLNTPNNPLGKVFSRE-ELELVASLCQQHDVVCITDEVYQWMVY 221 D L T T A +L G L+ +C++ +V+ + DE+ + Sbjct: 171 DLEALKAAITPNTAAFILEPIQGEAGINIPPAGFLKEALEVCKKENVLFVADEIQTGLGR 230 Query: 222 DGHQHISIASLPGMWERTLT-IGSAGKTFSATGWKVGWVLGPDHIMKHLRTVHQNSVFHC 280 G W+ + GK + + I+ S F Sbjct: 231 TGK------VFACDWDNVTPDMYILGKALGGGVFPISCAAANRDILGVFEPGSHGSTFGG 284 Query: 281 PTQSQAAVAESFE--REQLLFRQPSSYFVQFPQAMQRCRDHMIRSLQSVGLKP 331 + A + E E+ L + + ++ + MI ++ GL Sbjct: 285 NPLACAVSIAALEVLEEEKLTERSLQLGEKLVGQLKEIDNPMITEVRGKGLFI 337 >3LVM-A nrPDB Length = 423 Score = 40.6 bits (93), Expect = 0.001, Method: Composition-based stats. Identities = 44/347 (12%), Positives = 95/347 (27%), Gaps = 48/347 (13%) Query: 86 QEIDPLRNVLVTVGGYGALFTAFQALVD----EGDEVIIIEPFFDCYEPMTMMAGGRPVF 141 DP R ++ T G + A + + +G +I + Sbjct: 81 VGADP-REIVFTSGATESDNLAIKGAANFYQKKGKHIITSKTEHKAVLDTCRQLEREGFE 139 Query: 142 VSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVAS 201 V+ L N +D EL T + + NN +G V +++ + Sbjct: 140 VT---------YLAPQRNGIIDLKELEAAMRDDTILVSIMHVNNEIGVV---QDIAAIGE 187 Query: 202 LCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTIGSAG--KTFSATGWKVGWV 259 +C+ ++ D G I ++ L + + S K + G +G + Sbjct: 188 MCRARGIIYHVDAT----QSVGKLPIDLSQLK------VDLMSFSGHKIYGPKG--IGAL 235 Query: 260 LGPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFPQAMQRCRDH 319 + +S +R + ++ R+ Sbjct: 236 YVRRKPRVRIEAQMHGGGHERGMRSGTLPVHQIVGMGEAYRIAKEEMATEMERLRGLRNR 295 Query: 320 MIRSLQSVGLKPIIPQGSYFLITDISDFKRKMPDLPGAVDEPYDRRFVKWMIK-NKGLVA 378 + ++ + +L D+ + ++ E + + G Sbjct: 296 LWNGIKDIEE--------VYLNGDLEHGAPNILNVSFNYVEGESLIMALKDLAVSSGSAC 347 Query: 379 IPVSIFYSV------PHQKHFDHYIRFCF--VKDEATLQAMDEKLRK 417 S+ S + + IRF E + E +RK Sbjct: 348 TSASLEPSYVLRALGLNDELAHSSIRFSLGRFTTEEEIDYTIELVRK 394 >5WGB-A nrPDB Length = 426 Score = 40.6 bits (93), Expect = 0.001, Method: Composition-based stats. Identities = 37/260 (14%), Positives = 75/260 (28%), Gaps = 48/260 (18%) Query: 73 TKILASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMT 132 + +AS G DP R ++ T G + A + + F+ + Sbjct: 76 RQQVASLIG------ADP-REIIFTSGATESNNIAIKGVAR----------FYRSRKKHL 118 Query: 133 MMAGGRPVFV-----SLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPL 187 + V SL+ Q L + +D EL T + + T NN + Sbjct: 119 ITTQTEHKCVLDSCRSLEAEGFQVTYLPVQKSGIIDLKELEAAIQPDTSLVSVMTVNNEI 178 Query: 188 GKVFSREELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLP-GMWERTLTIGSAG 246 G ++ + + +C V TD ++ +P + + + + S Sbjct: 179 GV---KQPIAEIGRICSSRKVYFHTDAA-----------QAVGKIPLDVNDMKIDLMSIS 224 Query: 247 --KTFSATGWKVGWVLGPDHIMKHLRTVHQN-------SVFHCPTQSQAAVAESFEREQL 297 K + G VG + + + PT + + E Q Sbjct: 225 GHKIYGPKG--VGAIYIRRRPRVRVEALQSGGGQERGMRSGTVPTPLVVGLGAACEVAQQ 282 Query: 298 LFRQPSSYFVQFPQAMQRCR 317 + + + + Sbjct: 283 EMEYDHKRISKLSERLIQNI 302 >3NTJ-A nrPDB Length = 422 Score = 40.2 bits (92), Expect = 0.002, Method: Composition-based stats. Identities = 31/175 (17%), Positives = 63/175 (36%), Gaps = 11/175 (6%) Query: 163 DPMELAGKFTSRTKALVLNTP-NNPLGKVFSRE-ELELVASLCQQHDVVCITDEVYQWMV 220 D L + + P G + + VASLC++++V+ + DEV + Sbjct: 181 DLEALEKELQDPNVCAFIVEPVQGEAGVIVPSDSYFPGVASLCKKYNVLFVADEVQTGLG 240 Query: 221 YDGHQHISIASLPGMWERTLTIGSAGKTFSATGWKVGWVLGPDHIMKHLRTVHQNSVFHC 280 G + G+ + +G K S + + +L D +M L+ S + Sbjct: 241 RTGK--LLCTHHYGVKPDVILLG---KALSGGHYPISAILANDDVMLVLKPGEHGSTYGG 295 Query: 281 PTQSQAAVAESFE---REQLLFRQPSSYFVQFPQAMQRCRD-HMIRSLQSVGLKP 331 + A E+ + E+L ++ +D ++R ++ GL Sbjct: 296 NPLAAAICVEALKVLINEKLCENADKLGAPFLQNLKEQLKDSKVVREVRGKGLLC 350 >1VJO-A nrPDB Length = 393 Score = 40.2 bits (92), Expect = 0.002, Method: Composition-based stats. Identities = 41/268 (15%), Positives = 74/268 (27%), Gaps = 41/268 (15%) Query: 83 LLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPVFV 142 + + + V+ G A+ V+ GD V+I + + MAG V Sbjct: 77 RYVWQTENPLTIAVSGTGTAAMEATIANAVEPGDVVLIGVAGYFG-NRLVDMAGRYGADV 135 Query: 143 SLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASL 202 P L+ T R L L G R+ LE V L Sbjct: 136 RTISKPWGEVFSLEELRTALE--------THRPAILALVHAETSTGA---RQPLEGVGEL 184 Query: 203 CQQHDVVCITDEVYQ-------------WMVYDGHQHISIASLPGMWERTLTIGSAGKTF 249 C++ + + D V + Y + PG T++ + K Sbjct: 185 CREFGTLLLVDTVTSLGGVPIFLDAWGVDLAYS-CSQKGLGCSPGASPFTMSSRAIEKLQ 243 Query: 250 S----ATGWKVGWVLGPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSY 305 W +++ + P A+ E+ Sbjct: 244 RRRTKVANW-----YLDMNLLGKYWGSERVYHHTAPINLYYALREAL------RLIAQEG 292 Query: 306 FVQFPQAMQRCRDHMIRSLQSVGLKPII 333 Q Q+ +++ L+ +GL + Sbjct: 293 LANCWQRHQKNVEYLWERLEDIGLSLHV 320 >3GZD-A nrPDB Length = 440 Score = 39.8 bits (91), Expect = 0.002, Method: Composition-based stats. Identities = 41/321 (12%), Positives = 101/321 (31%), Gaps = 60/321 (18%) Query: 41 PPPDFAVEAFQHAV--SGDFMLNQYTKTFGYPPLTKILASFFGELLGQEIDPLRNVLVTV 98 P ++A A+ + + Y+ + +++G + ++++ T Sbjct: 36 PLEPEVIQAMTKAMWEAWGNPSSPYSAGRKAKDIINAARESLAKMIGGKP---QDIIFTS 92 Query: 99 GGYGALFTAFQALVD--------------EGDEVIIIEPFF--------DCYEPMTMMAG 136 GG + ++V V +P F P+ + Sbjct: 93 GGTESNNLVIHSVVKHFHANQTSKGHTGGHHSPVKGAKPHFITSSVEHDSIRLPLEHLVE 152 Query: 137 GRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFS---- 192 + V+ P +G+ + ++ T+ + + NN G V Sbjct: 153 EQVAAVTFVPVSKVSGQT--------EVDDILAAVRPTTRLVTIMLANNETGIVMPVPEI 204 Query: 193 REELELV--ASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTIGSAGKTFS 250 + ++ + + + + + Q + G Q + + L + LTI K + Sbjct: 205 SQRIKALNQERVAAGLPPILVHTDAAQAL---GKQRVDVEDLGVDF---LTIVGH-KFY- 256 Query: 251 ATGWKVGWVLGP-----DHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSY 305 G ++G + + L Q F T++ +A + +L+ + +Y Sbjct: 257 --GPRIGALYIRGLGEFTPLYPMLFGGGQERNFRPGTENTPMIAGLGKAAELVTQNCEAY 314 Query: 306 FVQFPQAMQRCRDHMIRSLQS 326 RD++ L++ Sbjct: 315 EAHMRDV----RDYLEERLEA 331 >4OTL-A nrPDB Length = 423 Score = 39.8 bits (91), Expect = 0.002, Method: Composition-based stats. Identities = 48/303 (15%), Positives = 91/303 (30%), Gaps = 45/303 (14%) Query: 44 DFAVEAFQHAVSGDFMLNQYTKTFGYPPLT------------KILASFFGELLGQEIDPL 91 + A G + N+Y GYP ++ +L G E Sbjct: 45 ENYTSPAVMAAQGSQLTNKY--AEGYPGKRYYGGCEYVDVVEQLAIDRVKQLFGAE---A 99 Query: 92 RNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPIQN 151 NV G A F A++ GD ++ + G PV +S K + + Sbjct: 100 ANVQPNSGS-QANQGVFFAMLKPGDTIMG-----MSLAHGGHLTHGSPVNMSGKWFNVVS 153 Query: 152 GELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSRE-ELELVASLCQQHDVVC 210 L + + +D L++ F+ + + E +A + + Sbjct: 154 YGLNENED--IDYDAAEKLANEHKPKLIVA-----GASAFALKIDFERLAKIAKSVGAYL 206 Query: 211 ITDEV-YQWMVYDGHQHISIASLPGMWERTLTIGSAGKTFSATGWKVGWVLGPDHIMKHL 269 + D Y ++ G + + K S G + G +L K + Sbjct: 207 MVDMAHYAGLIAAGVYPNPVPHAD------FVTTTTHK--SLRGPRGGVILMKAEYEKPI 258 Query: 270 RTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFPQAMQRCRDHMIRSLQSVGL 329 + + P A +E L S F ++ Q + + +L GL Sbjct: 259 NSAIFPGIQGGPLMHVIAAKAVAFKEAL-----SPEFKEYQQKVVENARVLAETLVKRGL 313 Query: 330 KPI 332 + + Sbjct: 314 RIV 316 >4Q6R-A nrPDB Length = 511 Score = 39.8 bits (91), Expect = 0.003, Method: Composition-based stats. Identities = 30/159 (18%), Positives = 53/159 (33%), Gaps = 23/159 (14%) Query: 69 YPPLTKILASFFGELLGQ-EIDPLRNVLVTVGGYGALFTAFQAL----VDEG---DEVII 120 +P L KI A P VT GG ++ A +A ++G E++ Sbjct: 121 FPGLRKIEAEIVRIACSLFNGGPDSCGCVTSGGTESILMACKAYRDLAFEKGIKTPEIVA 180 Query: 121 IEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVL 180 + + G + V V L + ++D + + T LV Sbjct: 181 PQSAHAAFNKAASYFGMKIVRVPL------------TKMMEVDVRAMRRAISRNTAMLVC 228 Query: 181 NTPNNPLGKVFSREELELVASLCQQHDVVCITDEVYQWM 219 +TP P G + + + VA L ++ + D Sbjct: 229 STPQFPHGVI---DPVPEVAKLAVKYKIPLHVDACLGGF 264 >3RI6-A nrPDB Length = 430 Score = 39.4 bits (90), Expect = 0.003, Method: Composition-based stats. Identities = 24/124 (19%), Positives = 43/124 (34%), Gaps = 25/124 (20%) Query: 95 LVTVGG-YGALFTAFQALVDEGDEVIIIEPFF----DCYEPMTMMAGGRPVFVSLKPGPI 149 ++ +G A+ TA L GD V+ + F ++ G FV + Sbjct: 100 VLALGSGMAAISTAILTLARAGDSVVTTDRLFGHTLSLFQKTLPSFGIEVRFVDV----- 154 Query: 150 QNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQQHDVV 209 +D + + TK L L T +NP +V LE ++ + + Sbjct: 155 ------------MDSLAVEHACDETTKLLFLETISNPQLQVAD---LEALSKVVHAKGIP 199 Query: 210 CITD 213 + D Sbjct: 200 LVVD 203 >4OBV-D nrPDB Length = 490 Score = 39.0 bits (89), Expect = 0.004, Method: Composition-based stats. Identities = 27/172 (15%), Positives = 64/172 (37%), Gaps = 16/172 (9%) Query: 74 KILASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTM 133 + + + + +G +P + GG A AL D + + + Sbjct: 135 QEVLKWLAKQVGFTENPGG--VFVSGGSMAN---ITALTAARDNKLTDI---NLHLGTAY 186 Query: 134 MAGGRPVFVS--LKPGPIQNGEL---GSSSNWQLDPMELAGKFTSRTK---ALVLNTPNN 185 ++ V+ L+ I + + ++S++Q+D +L + K + Sbjct: 187 ISDQTHSSVAKGLRIIGITDSRIRRIPTNSHFQMDTTKLEEAIETDKKSGYIPFVVIGTA 246 Query: 186 PLGKVFSREELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWE 237 S + L +++LC++HD+ D Y V ++ S+ + G+ + Sbjct: 247 GTTNTGSIDPLTEISALCKKHDMWFHIDGAYGASVLLSPKYKSLLTGTGLAD 298 >3NNK-A nrPDB Length = 411 Score = 39.0 bits (89), Expect = 0.004, Method: Composition-based stats. Identities = 26/184 (14%), Positives = 52/184 (28%), Gaps = 25/184 (13%) Query: 32 NLGQGFPDFPPPDFAVEAFQHAVSGDFMLNQYTKTFGYPPLTKILASFFGELLGQEIDPL 91 L G + A + G QY P +T + G Sbjct: 14 RLLMGPGPINADPRVLRAMSSQLIG-----QY-----DPAMTHYMNEVMALYRGVFRTEN 63 Query: 92 RNVLVTVG-GYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPIQ 150 R ++ G + + + GD+V++ P F + + R + Sbjct: 64 RWTMLVDGTSRAGIEAILVSAIRPGDKVLV--PVFGRFGHLLCEIARRCR------AEVH 115 Query: 151 NGELGSSSNWQLD-PMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQQHDVV 209 E+ + D + + R V + L + +C+++D + Sbjct: 116 TIEVPWGEVFTPDQVEDAVKRIRPRLLLTV----QGDTSTTM-LQPLAELGEICRRYDAL 170 Query: 210 CITD 213 TD Sbjct: 171 FYTD 174 >2EH6-A nrPDB Length = 375 Score = 39.0 bits (89), Expect = 0.004, Method: Composition-based stats. Identities = 55/335 (16%), Positives = 112/335 (33%), Gaps = 52/335 (15%) Query: 20 EFVKLASEHDVVNLGQGFPDFPPPDFAVEAFQHAVSGDFMLNQYTKTFGYPPLTKILASF 79 E++ S V +LG +P EA + V ++ + P + LA Sbjct: 29 EYLDFVSGIGVNSLGHAYPKL------TEALKEQVEKLLHVSNLYEN----PWQEELAHK 78 Query: 80 FGELLGQEIDPLRNVLVTVGGYGALFTAFQA----LVDEGD---EVIIIEPFFDCYEPMT 132 + E V G ++ A + D+G + I E F + Sbjct: 79 LVKHFWTEGK----VFFANSGTESVEAAIKLARKYWRDKGKNKWKFISFENSFHGRTYGS 134 Query: 133 MMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKV-F 191 + A G+P F + + D + T +++ G Sbjct: 135 LSATGQPKFHKGFEPLVPGFSYAKLN----DIDSVYKLLDEETAGIIIEVIQGEGGVNEA 190 Query: 192 SREELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTIGSAGKTFSA 251 S + L + +C++ DV+ I DEV + G + + + + K Sbjct: 191 SEDFLSKLQEICKEKDVLLIIDEVQTGIGRTG-EFYAYQHFNLKPDVI----ALAKGLG- 244 Query: 252 TGWKVGWVLGPDHIMKHLR-TVHQNSVFHCPTQSQAAVAESFEREQLL--FRQPSSYFVQ 308 G +G +L + + + H ++ P +A E E+LL R+ +YF + Sbjct: 245 GGVPIGAILAREEVAQSFTPGSHGSTFGGNPLACRAGTVVVDEVEKLLPHVREVGNYFKE 304 Query: 309 FPQAM-----------------QRCRDHMIRSLQS 326 + + + C+D+++++L+ Sbjct: 305 KLKELGKGKVKGRGLMLGLELERECKDYVLKALEK 339 >5TXT-B nrPDB Length = 491 Score = 39.0 bits (89), Expect = 0.004, Method: Composition-based stats. Identities = 33/198 (16%), Positives = 67/198 (33%), Gaps = 40/198 (20%) Query: 163 DPMELAGKF----TSRTKALVLNTPNNPLGKVFSREELELVASLCQQHDVVCITDEVYQ- 217 D EL S K + + + G V +E + L ++ + DEV+ Sbjct: 173 DLNELEQLLQSYPKSVPKLIAFESVYSMAGSVAD---IEKICDLADKYGALTFLDEVHAV 229 Query: 218 ------------WMVYDGHQHISIAS--------LPGMWERT-LTIGSAGKTFSATGWKV 256 ++ H+ IA+ + +R + G+ GK+F + G Sbjct: 230 GLYGPHGAGVAEHCDFESHRASGIATPKTNDKGGAKTVMDRVDMITGTLGKSFGSVG--- 286 Query: 257 GWVLGPDHIMKHLRTVHQNSVFHCPT-QSQAAVAESFEREQLLFRQPSSYFVQFPQAMQR 315 G+V ++ R+ +F S A A + R Q + + Q+ Sbjct: 287 GYVAASRKLIDWFRSFAPGFIFTTTLPPSVMAGATAAIRYQRCH-------IDLRTSQQK 339 Query: 316 CRDHMIRSLQSVGLKPII 333 ++ ++ +G+ I Sbjct: 340 HTMYVKKAFHELGIPVIP 357 >5YKR-A nrPDB Length = 461 Score = 39.0 bits (89), Expect = 0.004, Method: Composition-based stats. Identities = 44/318 (13%), Positives = 94/318 (29%), Gaps = 32/318 (10%) Query: 80 FGELLGQEIDPLRNVLVTVGGYGALFTAFQA--LVDEGDEVIIIEPFFDCYEPMT----M 133 G P V T A + ++ D+V++ + + Sbjct: 124 LARRFGL---PYWQV--TTSATDANRFVLRLCRMLSGRDKVVVFNCNYHGSVDESQVEFD 178 Query: 134 MAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTP--NNPLGKVF 191 AG + P +++ + D L A VL P N +G V Sbjct: 179 AAGRMVPRAGVHPNGVRHATTTRLVEFN-DLDALEAALAHGDVAAVLTEPFMTN-VGMVP 236 Query: 192 SREELEL-VASLCQQHDVVCITDEVY----QWMVYDGHQHISIASLPGMWERTLTIGSAG 246 E + L ++HDV I DE + Y G + + + + G Sbjct: 237 PAEGFHAGLRELTRRHDVALIIDETHTISCGPAGYSGAHGLEPDFF--VLGKCIAGGIPS 294 Query: 247 KTFSAT---GWKVGWVLGPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPS 303 + + ++ W + P N T + A+ + R Sbjct: 295 AVWGCSQAQAERI-WAVLPHFRPGQAI----NHFGFGGTLAGNALQLAAMRATFAEVMTE 349 Query: 304 SYFVQFPQAMQRCRDHMIRSLQSVGLKPIIPQ-GSYFLITDISDFKRKMPDLPGAVDEPY 362 + Q + + +L+ + L + + G+ ++ R + A + Sbjct: 350 DAYRHMFQLAAQLEAGVRATLEELRLPWHVTRIGARVEYLFMTHAPRNGGEAHHARNGLI 409 Query: 363 DRRFVKWMIKNKGLVAIP 380 + +++ +G++ P Sbjct: 410 EACLHLYLLN-RGVLLTP 426 >3WKR-A nrPDB Length = 416 Score = 38.6 bits (88), Expect = 0.005, Method: Composition-based stats. Identities = 27/242 (11%), Positives = 73/242 (30%), Gaps = 29/242 (11%) Query: 96 VTVGGYGALFTAFQALVDEGDEVIII-EPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGEL 154 T G F A+ EGD V++ + Y + + Sbjct: 117 PTHGAREGKFIVMHAICKEGDYVVLDKNAHYTSYVAAER---AKLNVAEVGYEEEYPTYK 173 Query: 155 GSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQQHDVVCITDE 214 + ++ L K ++L + G+ + + + V + ++ + + + Sbjct: 174 INLEGYKEVIDNLEDK-GKNVGLILLTHVD---GEYGNLNDAKKVGKIAKEKGIPFLLNC 229 Query: 215 VYQWMVYDGHQHISIASLPGMWERTLTIGSAGKTFSATGWKVGWVLGPDHIMKHLRT--- 271 Y + + + + G SA G + + + Sbjct: 230 AYT------VGRMPVNGKEVKADFIVASGHKSMAASAP---CGILAFSEEFSDKITKTSE 280 Query: 272 ---VHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFPQAMQRCRDHMIRSLQSVG 328 V + + C ++ V ++ R ++ + +++ R +++ L+ +G Sbjct: 281 KFPVKEIEMLGCTSRGLPIVTLMASFPHVVER-----VKKWDEELKKTR-YVVDELEKIG 334 Query: 329 LK 330 K Sbjct: 335 FK 336 >2DKJ-A nrPDB Length = 407 Score = 38.6 bits (88), Expect = 0.005, Method: Composition-based stats. Identities = 38/299 (12%), Positives = 83/299 (27%), Gaps = 38/299 (12%) Query: 44 DFAVEAFQHAVSGDFMLNQYTKT--FGYPPLTKILASFFGELLGQEIDPLRNVLVTVGGY 101 EA ++ + Y +G + + S E + G Sbjct: 37 KQVREAVGSVLTNKY-AEGYPGARYYGGCEVIDRVESLAIERAKALFGAAWANVQPHSGS 95 Query: 102 GALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQ 161 A + AL++ GD ++ D + G R F + G + Sbjct: 96 QANMAVYMALMEPGDTLM----GMDLAAGGHLTHGSRVNFSGKLYKVVSYGVRPDTE--L 149 Query: 162 LDPMELAGKFTSRTKALVLNTPNNPLGKVFSRE--ELELVASLCQQHDVVCITDEVY-QW 218 +D E+ +++ G + + + + + D + Sbjct: 150 IDLEEVRRLALEHRPKVIV------AGASAYPRFWDFKAFREIADEVGAYLVVDMAHFAG 203 Query: 219 MVYDGHQHISIASLPGMWERTLTIGSAGKTFSATGWKVGWVLGPD-HIMKHLRTVHQNSV 277 +V G + + +T + KT + G +L D + K + + + Sbjct: 204 LVAAGLHPNPLP-----YAHVVT-STTHKTLRGP--RGGLILSNDPELGKRIDKLIFPGI 255 Query: 278 FHCP---TQSQAAVAESFEREQLLFRQPSSYFVQFPQAMQRCRDHMIRSLQSVGLKPII 333 P + AVA F F ++ + + + L G + + Sbjct: 256 QGGPLEHVIAGKAVA--------FFEALQPEFKEYSRLVVENAKRLAEELARRGYRIVT 306 >3HMU-A nrPDB Length = 472 Score = 38.6 bits (88), Expect = 0.005, Method: Composition-based stats. Identities = 76/450 (16%), Positives = 135/450 (30%), Gaps = 64/450 (14%) Query: 5 LQARRLDGIDYNPWVEFVKLASEHDVVNLGQGFPDFPPPDFAVEAFQHAVSGDFMLNQYT 64 + R ++ + E + + VN+G G D E + N + Sbjct: 41 ITRARGVWLNDSEGEEILDAMAGLWCVNIGYGR------DELAEVAARQMRELPYYNTFF 94 Query: 65 KTFGYPPLTKILASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQALV-------DEGDE 117 KT P + LA EL ++ +V GG A T + + Sbjct: 95 KTTHVPAI--ALAQKLAELAPGDL---NHVFFAGGGSEANDTNIRMVRTYWQNKGQPEKT 149 Query: 118 VIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNW-----QLDPME------ 166 VII + A G + + G I + + NW +DP E Sbjct: 150 VIISRKNAYHGSTVASSALGGMAGMHAQSGLIPDVHHINQPNWWAEGGDMDPEEFGLARA 209 Query: 167 --LAGKF---TSRTKALVLNTPNNPLGKVF--SREELELVASLCQQHDVVCITDEVYQWM 219 L A + P G V + +C ++D++ I DEV Sbjct: 210 RELEEAILELGENRVAAFIAEPVQGAGGVIVAPDSYWPEIQRICDKYDILLIADEVICGF 269 Query: 220 VYDGHQHISIASLPGMWERTLTIG-SAGKTFSATGWKVGWVLGPD--HIMKHLRTVHQNS 276 G+ + G+ +TI ++ G G ++ + H++ H + Sbjct: 270 GRTGNWFGT--QTMGIRPHIMTIAKGLSSGYAPIG---GSIVCDEVAHVIGKDEFNHGYT 324 Query: 277 VFHCPTQSQAAVAES--FEREQLLFRQPSSYFVQFPQAMQRCRDH-------MIRSLQSV 327 P + A+ E E +L + + + DH ++ + S+ Sbjct: 325 YSGHPVAAAVALENLRILEEENILDHVRNVAAPYLKEKWEALTDHPLVGEAKIVGMMASI 384 Query: 328 GLKPIIPQGSYFLITDISDFKRKMPDLPGAVDEPYDRRFVKWMIKNKGLVAIPVSIFYSV 387 L P + F + + R MI + LV P I Sbjct: 385 ALTPNKASRAKF--ASEPGTIGYICRERCFANNLIMRHVGDRMIISPPLVITPAEID--- 439 Query: 388 PHQKHFDHYIRFCFVKDEATLQAMDEKLRK 417 + ++R DEA + + L K Sbjct: 440 ------EMFVRIRKSLDEAQAEIEKQGLMK 463 >6JEQ-A nrPDB Length = 675 Score = 37.9 bits (86), Expect = 0.008, Method: Composition-based stats. Identities = 16/64 (25%), Positives = 26/64 (40%), Gaps = 4/64 (6%) Query: 183 PNNPLGKVFSREELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTI 242 P+NP ++ EL+ + + I D VY VYDG+ +PG + R Sbjct: 252 PHNPAARIL---ELKRLIQKLHARGLRVIMDVVYNH-VYDGYLIHFTKLVPGYYLRYKAD 307 Query: 243 GSAG 246 + Sbjct: 308 RTFS 311 >6ERK-A nrPDB Length = 451 Score = 37.9 bits (86), Expect = 0.009, Method: Composition-based stats. Identities = 30/154 (19%), Positives = 57/154 (37%), Gaps = 19/154 (12%) Query: 191 FSREELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTIGSAGKTFS 250 +S + L+L+ LC ++DV+ I DE+ G + +TIG + Sbjct: 245 YSPQYLQLLRKLCDEYDVLLIADEIATGFGRSGKLFA--CEHAAISPDIMTIGK-----A 297 Query: 251 ATGWKVGWV-----LGPDHIMKHLRTVHQNSVFHCPTQSQ--AAVAESFEREQLLFRQPS 303 TG G++ L I + ++ H PT A A + L+ Sbjct: 298 LTG---GYMTFAATLSTREIADTISQSDYPALMHGPTFMGNPLACAVACASIDLIVSYDI 354 Query: 304 SYFVQFPQAMQRCRDHMIRSLQSVGLKPIIPQGS 337 + QA+ + + ++ G+K + G+ Sbjct: 355 EARTENMQAIMN--EQLAPAVSLEGVKEVRCLGA 386 >2FNU-A nrPDB Length = 375 Score = 37.9 bits (86), Expect = 0.009, Method: Composition-based stats. Identities = 36/168 (21%), Positives = 63/168 (37%), Gaps = 26/168 (15%) Query: 51 QHAVSGDFMLNQYTKTFGYPPLTKILASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQA 110 + AV Q T+ + L F G + + L+T L+ F Sbjct: 16 KKAVLEVLNSKQLTQGKRSLLFEEALCEFLGVKHALVFNSATSALLT------LYRNFSE 69 Query: 111 LVDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGK 170 + +E+I F M + +G PVF +K ++ +D + L Sbjct: 70 FSADRNEIITTPISFVATANMLLESGYTPVFAGIK------------NDGNIDELALEKL 117 Query: 171 FTSRTKALV-LNTPNNPLGKVFSREELELVASLCQQHDVVCITDEVYQ 217 RTKA+V ++ GK E+E V LC++H + ++D + Sbjct: 118 INERTKAIVSVDY----AGKSV---EVESVQKLCKKHSLSFLSDSSHA 158 >1Z7D-A nrPDB Length = 433 Score = 37.9 bits (86), Expect = 0.009, Method: Composition-based stats. Identities = 28/175 (16%), Positives = 60/175 (34%), Gaps = 11/175 (6%) Query: 163 DPMELAGKFTSRTKALVLNTP-NNPLGKVFSRE-ELELVASLCQQHDVVCITDEVYQWMV 220 D L + + P G + + L+ V +C++++V+ + DEV + Sbjct: 200 DLEALEEELKDPNVCAFIVEPIQGEAGVIVPSDNYLQGVYDICKKYNVLFVADEVQTGLG 259 Query: 221 YDGHQHISIASLPGMWERTLTIGSAGKTFSATGWKVGWVLGPDHIMKHLRTVHQNSVFHC 280 G + + + +G K S + + VL D IM ++ S + Sbjct: 260 RTGK--LLCVHHYNVKPDVILLG---KALSGGHYPISAVLANDDIMLVIKPGEHGSTYGG 314 Query: 281 PTQSQAAVAESFE---REQLLFRQPSSYFVQFPQAMQRCRD-HMIRSLQSVGLKP 331 + + E+ E+L + +D ++R ++ GL Sbjct: 315 NPLAASICVEALNVLINEKLCENAEKLGGPFLENLKRELKDSKIVRDVRGKGLLC 369 >2E54-A nrPDB Length = 385 Score = 37.9 bits (86), Expect = 0.010, Method: Composition-based stats. Identities = 32/174 (18%), Positives = 61/174 (35%), Gaps = 12/174 (6%) Query: 163 DPMELAGKFTSRTKALVLNTPNNPLGKV-FSREELELVASLCQQHDVVCITDEVYQWMVY 221 + +L K + A+ L G V ++E LE LC ++D + + DEV M Sbjct: 160 NVEDLRRKMSEDVCAVFLEPIQGESGIVPATKEFLEEARKLCDEYDALLVFDEVQCGMGR 219 Query: 222 DGHQHISIASLPGMWERTLTIGSAGKTFSATGWKVGWVLGPDHIMKHLRTVHQNSVFHCP 281 G + + + K G +G V+ + H + P Sbjct: 220 TGKLFAY-----QKYGVVPDVLTTAKGLG-GGVPIGAVIVNERANVLEPGDHGTTFGGNP 273 Query: 282 TQ--SQAAVAESFEREQLLF--RQPSSYFVQFPQAMQRCRDHMIRSLQSVGLKP 331 + V + +E L + +Y ++ Q M+ D + ++ +GL Sbjct: 274 LACRAGVTVIKELTKEGFLEEVEEKGNYLMKKLQEMKEEYDVVAD-VRGMGLMI 326 >5VYE-A nrPDB Length = 346 Score = 37.5 bits (85), Expect = 0.010, Method: Composition-based stats. Identities = 50/340 (14%), Positives = 104/340 (30%), Gaps = 45/340 (13%) Query: 54 VSGDFMLNQYTKTFGYPPLTKILASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQALVD 113 + + + + + +G T+ + +F L + V G A A +L Sbjct: 22 AAMEKANHGHDRAYGDDQWTERASEYFRNLFETDC----EVFFAFNGTAANSLALASLCQ 77 Query: 114 EGDEVII-----------IEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQL 162 VI P F + + + V L P I+ L Sbjct: 78 SYHSVICSETAHVETDECGAPEF--FSNGSKLLTAASVNGKLTPQSIREVALKRQDIHYP 135 Query: 163 DPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQQHDVVCITDEVYQWMVYD 222 P + T T+ G V+ +EL+ +++ C++ + + D Sbjct: 136 KPRVVT--ITQATEV----------GTVYRPDELKAISATCKELGL---------NLHMD 174 Query: 223 GHQHISIASLPGMWERTLTIGSAGKTFSATGWKVGWVLGPDHIMKHLRTVHQNSVFHCPT 282 G + + + G LT + G K G +G + I+ R + ++ + C Sbjct: 175 GARFTNACAFLGCSPAELTWKAGVDVLCFGGTKNGMAVG-EAILFFNRQLAEDFDYRCKQ 233 Query: 283 QSQAAVAESFEREQLL-FRQPSSYFVQ--FPQAMQRCRDHMIRSLQSVGLK-PIIPQGSY 338 Q A F + + ++ + ++ L V L P+ G + Sbjct: 234 AGQLASKMRFLSAPWVGLLEDGAWLRHGNHANHCAQLLALLVSDLPGVELMFPVEANGVF 293 Query: 339 FLITD--ISDFKRKMPDLPGAVDEPYDRRFVKWMIKNKGL 376 + + I + K + R W + + + Sbjct: 294 LQMPEHAIEALRAKGWRFYTFIGSGGARFMCSWDTEEERV 333 >1O69-A nrPDB Length = 394 Score = 37.5 bits (85), Expect = 0.011, Method: Composition-based stats. Identities = 38/256 (14%), Positives = 88/256 (34%), Gaps = 32/256 (12%) Query: 69 YPPLTKILASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCY 128 PL + + F E ++ N L AL A + + D++++ F Sbjct: 27 IAPLGEFVNRF--EQSVKDYSKSENALALNSATAALHLALRVAGVKQDDIVLAS-SFTFI 83 Query: 129 EPMTMMA--GGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRT-KALVLNTPNN 185 + + +PVF+ + +D ++LA K + KAL+L Sbjct: 84 ASVAPICYLKAKPVFIDCDETYNID----------VDLLKLAIKECEKKPKALILT---- 129 Query: 186 PLGKVF-SREELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTIGS 244 ++ + +++ + +C+++D+V I D +L E + + Sbjct: 130 ---HLYGNAAKMDEIVEICKENDIVLIEDAA-----EALGSFYKNKALGTFGEFGVYSYN 181 Query: 245 AGKTFSATGWKVGWVLG-PDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPS 303 K + +G G ++G ++ R + +C ++ +L Sbjct: 182 GNKIITTSG--GGMLIGKNKEKIEKARFYSTQARENCLHYEHLDYGYNYRLSNVLGAIGV 239 Query: 304 SYFVQFPQAMQRCRDH 319 + Q + + R+ Sbjct: 240 AQMEVLEQRVLKKREI 255 >4EB7-A nrPDB Length = 382 Score = 37.1 bits (84), Expect = 0.014, Method: Composition-based stats. Identities = 23/165 (13%), Positives = 50/165 (30%), Gaps = 14/165 (8%) Query: 41 PPPDFAVEAFQHAVSGDFMLNQYTKTFGYPPLTKILASFFGELLGQEIDPLRNVLVTVGG 100 P + +EA ++ F ++G+ + + ++ V+ T G Sbjct: 11 PVDERILEAMLPYMTESFGNPSSVHSYGFKA-REAVQEAREKVAKLVNGGGGTVVFTSGA 69 Query: 101 YGALFTAF--QALVDE--GDEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGS 156 A A A+ + G +++ + V P Sbjct: 70 TEANNLAIIGYAMRNARKGKHILVSAVEHMSVINPAKFLQKQGFEVEYIPVGKYG----- 124 Query: 157 SSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVAS 201 ++D + K T + + NN +G + EE+ V + Sbjct: 125 ----EVDVSFIDQKLRDDTILVSVQHANNEIGTIQPVEEISEVLA 165 >6G4F-A nrPDB Length = 464 Score = 37.1 bits (84), Expect = 0.014, Method: Composition-based stats. Identities = 31/180 (17%), Positives = 63/180 (35%), Gaps = 12/180 (6%) Query: 151 NGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVF--SREELELVASLCQQHDV 208 E + ++ + T A + P G V R E + +C+++D+ Sbjct: 194 ESEEHFADRLAVELEQKILAEGPETIAAFIGEPLMGAGGVIVPPRTYWEKIQKVCRKYDI 253 Query: 209 VCITDEVYQWMVYDGHQHISIASLPGMWERTLTIGSAGKTFSATGWKVGWVLGPDHIMKH 268 + I DEV G S G+ + + K S++ + +L + + Sbjct: 254 LVIADEVICGFGRTGQMFGS--QTFGIQPDIMVL---SKQLSSSYQPIAAILINAPVFEG 308 Query: 269 LRTVHQ--NSVFHCPTQSQ--AAVAESFEREQLLFRQPS-SYFVQFPQAMQRCRDHMIRS 323 + Q ++ H T S A A + E +++ + + Q Q ++ H I Sbjct: 309 IADQSQALGALGHGFTGSGHPVATAVALENLKIIEEESLVEHAAQMGQLLRSGLQHFIDH 368 >3MC6-C nrPDB Length = 497 Score = 36.7 bits (83), Expect = 0.018, Method: Composition-based stats. Identities = 22/138 (15%), Positives = 47/138 (34%), Gaps = 16/138 (11%) Query: 109 QALVDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELA 168 + + + E+I ++ G + V L P +Q+D ++ Sbjct: 154 RGITEP--EIIAPVTAHAGFDKAAYYFGMKLRHVELDPTT-----------YQVDLGKVK 200 Query: 169 GKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQQHDVVCITDEVYQWMVYDGHQHIS 228 T LV + PN P G +++E + + Q++ + D + + Sbjct: 201 KFINKNTVLLVGSAPNFPHGIA---DDIEGLGKIAQKYKLPLHVDSCLGSFIVSFMEKAG 257 Query: 229 IASLPGMWERTLTIGSAG 246 +LP + R + S Sbjct: 258 YKNLPLLDFRVPGVTSIS 275 >3ECD-A nrPDB Length = 425 Score = 36.7 bits (83), Expect = 0.019, Method: Composition-based stats. Identities = 34/287 (11%), Positives = 81/287 (28%), Gaps = 31/287 (10%) Query: 44 DFAVEAFQHAVSGDFMLNQYTKTF------GYPPLTKILASFFGELLGQEIDPLRNVLVT 97 + V G + N+Y + + G + + E + + + + Sbjct: 41 ENIVSRAVLDAQGSVLTNKYAEGYPGKRYYGGCEFADEVEALAIERVKRLFNAGHANVQP 100 Query: 98 VGGYGALFTAFQALVDEGDEVI---IIEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGEL 154 G A AL GD V+ + + ++G F +L+ G ++ L Sbjct: 101 HSGAQANGAVMLALAKPGDTVLGMSLDAGGHLTHGAKPALSGK--WFNALQYGVSRDTML 158 Query: 155 GSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSRE-ELELVASLCQQHDVVCITD 213 +D ++ +L++ + + R+ + ++ + D Sbjct: 159 -------IDYDQVEALAQQHKPSLIIAGFS-----AYPRKLDFARFRAIADSVGAKLMVD 206 Query: 214 EVYQWMVYDGHQHISIASLPGMWERTLTIGSAGKTFSATGWKVGWVLGPDHIMKHLRTVH 273 + V +H + + + KT + G+VL D + Sbjct: 207 MAHIAGVIAAGRHANPVEHAH-----VVTSTTHKTLRGP--RGGFVLTNDEEIAKKINSA 259 Query: 274 QNSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFPQAMQRCRDHM 320 ++ + L +Y + Q D + Sbjct: 260 VFPGLQGGPLMHVIAGKAVAFGEALTDDFKTYIDRVLANAQALGDVL 306 >5VIU-A nrPDB Length = 419 Score = 36.7 bits (83), Expect = 0.019, Method: Composition-based stats. Identities = 28/141 (19%), Positives = 49/141 (34%), Gaps = 11/141 (7%) Query: 196 LELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTIGSAGKTFSATGWK 255 L+ + LC++H+V+ I DEV + G IA + + I GK S + Sbjct: 223 LKQSSELCKKHNVLFIADEVQTGIARTGKL---IACHHEDVQPDILI--LGKALSGGMYP 277 Query: 256 VGWVLGPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFPQAMQR 315 V VL ++IM ++ S F + A + + Q + + + Sbjct: 278 VSAVLANNNIMDVIKPGQHGSTFGGNPLACAVAMAALDVVQ------DEKLSERAEKLGN 331 Query: 316 CRDHMIRSLQSVGLKPIIPQG 336 I L +G Sbjct: 332 LFRSEIEKLIEKTDLITKVRG 352 >2CY8-A nrPDB Length = 453 Score = 36.3 bits (82), Expect = 0.023, Method: Composition-based stats. Identities = 72/429 (16%), Positives = 125/429 (29%), Gaps = 56/429 (13%) Query: 13 IDYNPWVEFVKLASEHDVVNLGQGFPDFPPPDFAVEAFQHAVSGDFMLNQYTKTFGYPPL 72 +D N +++F H + LG G P EA H V QY + Sbjct: 54 VDGNVYLDFF---GGHGALVLGHGHPRVNA--AIAEALSHGV-------QYAASHPLEV- 100 Query: 73 TKILASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQ-ALVDEGDEVII----------- 120 + E + +R + T G A + A G +I+ Sbjct: 101 ------RWAERIVAAFPSIRKLRFTGSGTETTLLALRVARAFTGRRMILRFEGHYHGWHD 154 Query: 121 -IEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALV 179 ++ + G P + + G + ++A + Sbjct: 155 FSASGYNSHFDGQPAPGVLPETTANTLLIRPDDIEGMREVFANHGSDIAAFIAEPVGSHF 214 Query: 180 LNTPNNPLGKVFSREELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERT 239 TP S L A L +Q+ + I DEV H ++ + + Sbjct: 215 GVTP-------VSDSFLREGAELARQYGALFILDEVISGFRVGNHGMQALLDV----QPD 263 Query: 240 LTIGSAGKTFSATGWKVGWVLGPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLF 299 LT K SA G G + G + +M L V H T + + + + Sbjct: 264 LTC--LAKA-SAGGLPGGILGGREDVMGVLSRGSDRKVLHQGTFTGNPITAAAAIAAIDT 320 Query: 300 RQPSSYFVQFPQAMQRCRDHMIRSLQSVGLKPIIPQG---SYFLITDISDFKRKMPDLPG 356 + Q R+ M GL + G + L+ + + Sbjct: 321 ILEDDVCAKINDLGQFAREAMNHLFARKGLNWLA-YGRFSGFHLMPGLPPNTTDTGSITR 379 Query: 357 AVDEPYDRRFVKWMIKNKGLVAI----PVSIFYSVPHQKHFDHYIRFCFVKDEATLQAMD 412 A D + + M L + S+F S H++ ++ F + L D Sbjct: 380 AEVARPDVKMIAAMRMALILEGVDIGGRGSVFLSAQHEREHVEHLVTTFDRVLDRL--AD 437 Query: 413 EKLRKWKVE 421 E L W+ Sbjct: 438 ENLLSWQGT 446 >2EO5-A nrPDB Length = 419 Score = 36.3 bits (82), Expect = 0.025, Method: Composition-based stats. Identities = 38/328 (11%), Positives = 96/328 (29%), Gaps = 41/328 (12%) Query: 6 QARRLDGIDYNPWVEFVKLASEHDVVNLGQGFPDFPPPDFAVEAFQHAVSGDFMLNQYTK 65 Q ++L N + +L +V G +F F + A+ + + T Sbjct: 71 QMQKLAHAAANDFYNIPQLELAKKLVTYSPG--NFQKKVFFSNSGTEAIEASIKVVKNTG 128 Query: 66 TFGYPPLTKILASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFF 125 K + +F G G+ ++ +T A+ + G +I P+ Sbjct: 129 -------RKYIIAFLGGFHGRTF---GSISLT--ASKAVQRSIVGPFMPG---VIHVPYP 173 Query: 126 DCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNN 185 + Y + G + + + D + + + Sbjct: 174 NPYRNPWHINGYE----------NPSELVNRVIEFIEDYIFVNLVPPEEVAGIFFEPIQG 223 Query: 186 PLGKVFSREEL-ELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTIGS 244 G V + + L +++ ++ + DEV + G +I + + + + Sbjct: 224 EGGYVIPPKNFFAELQKLAKKYGILLVDDEVQMGLGRTGKLF-AIENFNTVPDVI----T 278 Query: 245 AGKTFSATGWKVGWVLGPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQL-LFRQPS 303 K +G + + H T A+A + + + + + Sbjct: 279 LAKALGGGIMPIGATIFRKDLDFK-------PGMHSNTFGGNALACAIGSKVIDIVKDLL 331 Query: 304 SYFVQFPQAMQRCRDHMIRSLQSVGLKP 331 + + + + ++ +GL Sbjct: 332 PHVNEIGKIFAEELQGLADDVRGIGLAW 359 >6CBN-A nrPDB Length = 438 Score = 36.3 bits (82), Expect = 0.027, Method: Composition-based stats. Identities = 50/289 (17%), Positives = 84/289 (29%), Gaps = 50/289 (17%) Query: 136 GGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREE 195 G P++ + N + + L + + R A+V++ P S Sbjct: 153 GYDPMWYPSEAPLEPNADGVVDFFFDLGLLRELLRAPERVAAVVVS----PDHMHLSPGW 208 Query: 196 LELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTIGSAGKTFSAT-GW 254 + LC VV + DEV + Y + P +W K G Sbjct: 209 YRELRRLCSAAGVVLVADEVKVGLRYAPGLSTAELLAPDVWVVA-------K--GMANGH 259 Query: 255 KVGWVLGPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFPQAMQ 314 V V G ++K L+ V S F + A A + R +A Sbjct: 260 AVSAVGGSRRLLKPLKEVSFTSFFEPTILAAADAALARVATGEPQR-------AVREAGD 312 Query: 315 RCRDHMIRSLQSVGLKP-IIPQGSYFLITDISDFKRKMPDLPGAVDEPYDRRFVKWMIKN 373 R H ++L L I G++F P + Y + ++ Sbjct: 313 RFLRHARKALDDASLPVEIAGDGTFFQFV---------PATEELEEALYGAANAEGLL-- 361 Query: 374 KGLVAIPVSIFYSVPHQKHFDHYIRFCFVKDEATLQAMDEKLRKWKVEL 422 FY+ +Q DEA L + + + L Sbjct: 362 ----------FYAGDNQG-------VSAAFDEAVLGEAERRFARVCERL 393 >3HQT-A nrPDB Length = 409 Score = 35.9 bits (81), Expect = 0.034, Method: Composition-based stats. Identities = 45/338 (13%), Positives = 99/338 (29%), Gaps = 55/338 (16%) Query: 76 LASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMA 135 + + G + L++ G+ A Q + V I D + M++ Sbjct: 109 IEKRLAKFTGFD-----ECLLSQSGWNANVGLLQTICQPNTNVYI-----DFFAHMSLWE 158 Query: 136 GGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSR-TKALVLNTPNNPLGKVFSRE 194 G R P N L +V+++ + LG + Sbjct: 159 GARYANAQAHPFMHNNC------------DHLRMLIQRHGPGIIVVDSIYSTLGTIAP-- 204 Query: 195 ELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTIGSAGKTFSATGW 254 L + ++ ++ + DE + + + +A L E S KTF+ + Sbjct: 205 -LAELVNISKEFGCALLVDESHSLGTHGPNGAGLLAELGLTREVHFMTASLAKTFA---Y 260 Query: 255 KVGWVLGPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFPQAMQ 314 + G + + + + + + ++F + A E + + Q + Sbjct: 261 RAGAIWCNNEVNRCVPFISYPAIFS--STLLPYEAAGLETTLEIIESADN----RRQHLD 314 Query: 315 RCRDHMIRSLQSVGLKPIIPQGSYFLITDISDFKRKMPDLPGAVDEPYDRRFVKWMIKNK 374 R + L +GL + + + + V+ +++ Sbjct: 315 RMARKLRIGLSQLGLTIR----------------SESQIIGLETGDERNTEKVRDYLESN 358 Query: 375 GLVAIPVSIFYSVPHQKHFDHYIRFCFVKDEATLQAMD 412 G+ S+F P + IR D Q Sbjct: 359 GVF---GSVFCR-PATSKNKNIIRLSLNSDVNDEQIAK 392 >3I5T-A nrPDB Length = 476 Score = 35.6 bits (80), Expect = 0.038, Method: Composition-based stats. Identities = 52/296 (17%), Positives = 91/296 (30%), Gaps = 56/296 (18%) Query: 76 LASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQ-------ALVDEGDEVIIIEPFFDCY 128 LA L ++ + T GG A+ +A + L + II+ +D Y Sbjct: 102 LAEKIATLTPGDL---NRIFFTTGGSTAVDSALRFSEFYNNVLGRPQKKRIIVR--YDGY 156 Query: 129 EPMTMMA-------GGRPVF------VSLKPGPIQNGELGSSSNWQLD-----PMELAGK 170 T + G P F +S P S LD + Sbjct: 157 HGSTALTAACTGRTGNWPNFDIAQDRISFLSSPNPRHAGNRSQEAFLDDLVQEFEDRIES 216 Query: 171 FTSRTKALVLNTPNNPLGKVF--SREELELVASLCQQHDVVCITDEVYQWMVYDGHQHIS 228 T A L P G V ++C++HD++ I+DEV G S Sbjct: 217 LGPDTIAAFLAEPILASGGVIIPPAGYHARFKAICEKHDILYISDEVVTGFGRCGEWFAS 276 Query: 229 IASLPGMWERTLTIGSAGKTFSATGWKVGWV-----LGPDHIMKHL--RTVHQNSVFHCP 281 ++ I + K G G+V + ++ + + + Sbjct: 277 ----EKVFGVVPDIITFAK-----GVTSGYVPLGGLAISEAVLARISGENAKGSWFTNGY 327 Query: 282 TQS--QAAVAESFEREQLLFRQPSSYFVQFPQAMQRCRDHMIRSLQSVGLKPIIPQ 335 T S A A + +L+ R+ + D+ +L S+ P + + Sbjct: 328 TYSNQPVACAAALANIELMEREG------IVDQAREMADYFAAALASLRDLPGVAE 377 >2FQ6-A nrPDB Length = 415 Score = 35.6 bits (80), Expect = 0.042, Method: Composition-based stats. Identities = 15/127 (11%), Positives = 40/127 (31%), Gaps = 19/127 (14%) Query: 94 VLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGE 153 VL G A+ + A +++GD V++ ++ + + + P+ Sbjct: 101 VLFPCGA-AAVANSILAFIEQGDHVLMTNTAYEPSQDFCSKILSKLGVTTSWFDPLIG-- 157 Query: 154 LGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQQ--HDVVCI 211 ++ TK + L + P ++ + + + D + + Sbjct: 158 -----------ADIVKHLQPNTKIVFLES---PGSITMEVHDVPAIVAAVRSVVPDAIIM 203 Query: 212 TDEVYQW 218 D + Sbjct: 204 IDNTWAA 210 >5LH9-A nrPDB Length = 458 Score = 35.6 bits (80), Expect = 0.042, Method: Composition-based stats. Identities = 27/174 (15%), Positives = 54/174 (31%), Gaps = 32/174 (18%) Query: 127 CYEPMTMMAGGRPVFVS-LKPGPIQNGELGSSSNWQL-DPMELAGKFTSRTKALVLNTPN 184 Y ++AG + L P + + + + E ++T A ++ P Sbjct: 174 HYNHGQLLAGCHLLDTPWLYRNPWDCRDPQALTAHCIRQLEEQIALLGAQTIAALIAEPV 233 Query: 185 NPLGKVF--SREELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTI 242 G V + + +C +H ++ I DEV + Sbjct: 234 QGAGGVIVPPADYWPRLREVCDRHGILLIADEV--------------------------V 267 Query: 243 GSAGKTFSATGWKVGWVLGPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQ 296 G++ G + GW + PD + +Q +A++ E Q Sbjct: 268 TGFGRSGCMLGSR-GWGVAPDILCLAKGITAGYIPLGATLFNQR-IADAIENGQ 319 >2CH1-A nrPDB Length = 396 Score = 35.6 bits (80), Expect = 0.047, Method: Composition-based stats. Identities = 44/273 (16%), Positives = 80/273 (29%), Gaps = 48/273 (17%) Query: 83 LLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVII-IEPFFDCYEPMTMMAGGRPVF 141 + + + V+ + + L++EGD V+I + + E M+ Sbjct: 61 RYIFQTENRATMCVSGSAHAGMEAMLSNLLEEGDRVLIAVNGIWA--ERAVEMSERYGAD 118 Query: 142 VSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVAS 201 V GP + ++ + K L L ++ G + LE V Sbjct: 119 VRTIEGPPDRPFSLETLARAIELHQ--------PKCLFLTHGDSSSGL---LQPLEGVGQ 167 Query: 202 LCQQHDVVCITDEVYQWMVYDGHQHISIASLP---GMWERTLTIGSAGKTFSA-TGWKVG 257 +C QHD + I D V S+ +P WE A K A G + Sbjct: 168 ICHQHDCLLIVDAV-----------ASLCGVPFYMDKWEIDAVYTGAQKVLGAPPG--IT 214 Query: 258 WVLGPDHIMKHLRTVHQNS---------------VFHCPTQSQAAVAESF--EREQLLFR 300 + + +R S + P + VA + + L + Sbjct: 215 PISISPKALDVIRNRRTKSKVFYWDLLLLGNYWGCYDEPKRYHHTVASNLIFALREALAQ 274 Query: 301 QPSSYFVQFPQAMQRCRDHMIRSLQSVGLKPII 333 + C + L +GL + Sbjct: 275 IAEEGLENQIKRRIECAQILYEGLGKMGLDIFV 307 >1DJ9-A nrPDB Length = 384 Score = 35.6 bits (80), Expect = 0.049, Method: Composition-based stats. Identities = 19/124 (15%), Positives = 32/124 (25%), Gaps = 2/124 (1%) Query: 192 SREELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTIGSAGKTFSA 251 L + + QQH+ + D+ + V S + L + + GK F Sbjct: 183 DSAPLAEIQQVTQQHNGWLMVDDAHGTGVIGEQGRGSC--WLQKVKPELLVVTFGKGFGV 240 Query: 252 TGWKVGWVLGPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFPQ 311 +G V + S P Q+QA A Sbjct: 241 SGAAVLCSSTVADYLLQFARHLIYSTSMPPAQAQALRASLAVIRSDEGDARREKLAALIT 300 Query: 312 AMQR 315 + Sbjct: 301 RFRA 304 >5M46-A nrPDB Length = 440 Score = 35.2 bits (79), Expect = 0.060, Method: Composition-based stats. Identities = 46/322 (14%), Positives = 92/322 (28%), Gaps = 39/322 (12%) Query: 20 EFVKLASEHDVVNLGQGFPDFPPPDFAVEAFQHAVSGDFMLNQYTKTFGYPPLTKILASF 79 E + L+ +LG G P +EA A + + + + P + LA Sbjct: 45 ELIDLSGAWGAASLGYGHP------AIIEAVSRAAANPAGASILSASN-APAV--ALAER 95 Query: 80 FGELL-GQEIDPLRNVLVTVGGYGALFTAFQ---------ALVDEGDEVIIIEPFFDCYE 129 G+ + A + A A + + F + Sbjct: 96 LTASFPGRGTHKVWFGHSGSDANEAAYRAITRATGRTGVIAFIGAYHGCTVGSMAFSGHS 155 Query: 130 PMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTS--RTKALVLNTPNNPL 187 A + + P P + + + + L ++ A + + Sbjct: 156 VQADAAKADGLILLPYPDPYRPYQDDPTGDAVLALLKERLAAVPAGSIAAAFIEPIQSDG 215 Query: 188 GKVFSRE-ELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTIGSAG 246 G + + L A +C+ H + + DEV + G H G L +G Sbjct: 216 GLIVPPDGFLRKFADICRAHGISVVCDEVKVGLARSGRLH--CFEHEGFVPDILVLGKGL 273 Query: 247 KTFSATGWKVGWVLGPDHIMKHLRTVHQNSVFHCPTQSQAAVA-----------ESFERE 295 V+ P I+ ++ P + A +A + ER+ Sbjct: 274 GGGLPL----SAVIAPAEILDCASAFAMQTLHGNPVCAAAGLAVLETIEAENLTTAAERK 329 Query: 296 QLLFRQPSSYFVQFPQAMQRCR 317 L R+ + + + + R Sbjct: 330 GKLLREGLARLAERHELIGDIR 351 >5LL2-A nrPDB Length = 480 Score = 34.8 bits (78), Expect = 0.069, Method: Composition-based stats. Identities = 32/143 (22%), Positives = 61/143 (42%), Gaps = 9/143 (6%) Query: 192 SREELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTIGSAGKTFSA 251 E ++LV C +H ++ DEV Q + G +I + + S GK+ + Sbjct: 259 PEEYMQLVYKFCHEHGILFAIDEVNQGLGRTGKMW-AIQQFKDIEPD---LMSVGKSLA- 313 Query: 252 TGWKVGWVLGPDHIMKHLRT-VHQNSVFHCPTQSQAAVA--ESFEREQLLFRQPSSYFVQ 308 +G + V+G +M+ L H + P S A++A + E E L+ + + Sbjct: 314 SGMPLSAVIGKKEVMQSLDAPAHLFTTAGNPVCSAASLATLDVIEYEGLVEKSATDGAYA 373 Query: 309 FPQAMQ-RCRDHMIRSLQSVGLK 330 + ++ + R MI ++ GL Sbjct: 374 KQRFLEMQQRHPMIGDVRMWGLN 396 >3DOD-A nrPDB Length = 448 Score = 34.8 bits (78), Expect = 0.081, Method: Composition-based stats. Identities = 48/290 (16%), Positives = 85/290 (29%), Gaps = 45/290 (15%) Query: 44 DFAVEAFQHAVSGDFMLNQYTKTFGYPPLTKILASFFGELLGQEIDPLRNVLVTVGGYGA 103 D EA + A+ F QY K G P K +A + V+VG Sbjct: 111 DSGAEAMEIALKMAF---QYWKNIGKPEKQKFIA--MKNGYHGDTIGA----VSVGSIE- 160 Query: 104 LFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLD 163 F + ++ E + + G P + + +L + ++ Sbjct: 161 ---LFHHVYGP----LMFESYKAPIPYVYRSESGDPDECRDQCLR-ELAQLLEEHHEEIA 212 Query: 164 PMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQQHDVVCITDEVYQWMVYDG 223 + + + + V L V LC +DV+ I DEV G Sbjct: 213 ALSIESMVQGASGMI-----------VMPEGYLAGVRELCTTYDVLMIVDEVATGFGRTG 261 Query: 224 HQHISIASLPGMWERTLTIGSAGKTFSATG--WKVGWVLGPDHIMKHL----RTVHQNSV 277 + + +AGK TG + + I K + Sbjct: 262 KMFA--CEHENVQPD---LMAAGK--GITGGYLPIAVTFATEDIYKAFYDDYENLKTFFH 314 Query: 278 FHCPTQSQAAVAESFEREQLLFRQPSSYFVQFPQAMQRCRDHMIRSLQSV 327 H T +Q A + E L S V+ + +++ L ++ Sbjct: 315 GHSYTGNQLGCAVALEN---LALFESENIVEQVAEKSKKLHFLLQDLHAL 361 >4E3Q-A nrPDB Length = 473 Score = 34.4 bits (77), Expect = 0.093, Method: Composition-based stats. Identities = 37/271 (13%), Positives = 77/271 (28%), Gaps = 38/271 (14%) Query: 86 QEIDPLR--NVLVTVGGYGALFTAFQAL----VDEGD----EVIIIEPFFDCYEPMTMMA 135 E+ P V T G A T + L EG +++ + ++ Sbjct: 121 VEVSPFDSGRVFYTNSGSEANDTMVKMLWFLHAAEGKPQKRKILTRWNAYHGVTAVSASM 180 Query: 136 GGRPV----------FVSLKPGPIQNGELGSSSNWQL------DPMELAGKFTSRTKALV 179 G+P FV L + Q + E + + T A Sbjct: 181 TGKPYNSVFGLPLPGFVHLTCPHYWRYGEEGETEEQFVARLARELEETIQREGADTIAGF 240 Query: 180 LNTPNNPLGKVFSRE--ELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWE 237 P G V + + + +++D+ I+DEV G+ Sbjct: 241 FAEPVMGAGGVIPPAKGYFQAILPILRKYDIPVISDEVICGFGRTGNTWG--CVTYDFTP 298 Query: 238 RTLTIGSAGKTFSATGWKVGWVLGPDHIMKHLRTVHQNSV----FHCPTQSQAAVAESFE 293 + + K +A + +G V+ + K L T + + A + + Sbjct: 299 DAII---SSKNLTAGFFPMGAVILGPELSKRLETAIEAIEEFPHGFTASGHPVGCAIALK 355 Query: 294 REQLLFRQP-SSYFVQFPQAMQRCRDHMIRS 323 ++ + + + + H+ Sbjct: 356 AIDVVMNEGLAENVRRLAPRFEERLKHIAER 386 >1I43-A nrPDB Length = 445 Score = 34.4 bits (77), Expect = 0.099, Method: Composition-based stats. Identities = 27/177 (15%), Positives = 56/177 (31%), Gaps = 28/177 (15%) Query: 162 LDPMELAGK----FTSRTKALVLNTPNNPLGKVFSREELELVASLCQQHDVVCITDEVYQ 217 +DP ++ + +P NP + +ELV+ LC + + D + Sbjct: 184 IDPADVGALELALNQKKVNLFFTESPTNPFLRCVD---IELVSKLCHEKGALVCIDGTFA 240 Query: 218 WMVYDGHQHISIASLPGMWERTLTIGSAGKTFS-----ATGWKVGWVLGPDHIMKHLRTV 272 + L + SA K G + GP ++ +R + Sbjct: 241 ---------TPLNQKALALGADLVLHSATKFLGGHNDVLAG----CISGPLKLVSEIRNL 287 Query: 273 HQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFPQAMQ---RCRDHMIRSLQS 326 H + + + L +Q +S ++ + ++ + R LQS Sbjct: 288 HHILGGALNPNAAYLIIRGMKTLHLRVQQQNSTALRMAEILEAHPKVRHVYYPGLQS 344 >4WXB-A nrPDB Length = 428 Score = 34.0 bits (76), Expect = 0.12, Method: Composition-based stats. Identities = 36/202 (17%), Positives = 58/202 (28%), Gaps = 33/202 (16%) Query: 44 DFAVEAFQHAVSGDFMLNQYTKTFGYPPLT-----------KILA-SFFGELLGQEIDPL 91 + V A G + N+Y GYP + LA +L G + Sbjct: 48 ENVVSKAVMAAQGTLLTNKY--AEGYPGKRYYGGTAVIDVVETLAIERAKKLFGAKFA-- 103 Query: 92 RNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPIQN 151 NV G A + +L+ GD V+ ++ + G PV S K + Sbjct: 104 -NVQPHSGS-QANAAVYMSLIQPGDTVMGMD-----LSAGGHLTHGAPVSFSGKTYNFVS 156 Query: 152 GELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSRE--ELELVASLCQQHDVV 209 + S LA R K +V G + + Sbjct: 157 YNVDKESELLDYDAILAQAKEVRPKLIV-------AGASAYSRIIDFAKFREIADAVGAY 209 Query: 210 CITDEVY-QWMVYDGHQHISIA 230 + D + +V GH + Sbjct: 210 LMVDMAHIAGLVASGHHPSPVP 231 >1SFF-A nrPDB Length = 426 Score = 33.6 bits (75), Expect = 0.14, Method: Composition-based stats. Identities = 32/226 (14%), Positives = 67/226 (29%), Gaps = 24/226 (10%) Query: 192 SREELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTIGSAGKTFSA 251 S ++ + +LC +H ++ I DEV G ++ + + T S F Sbjct: 218 SPAFMQRLRALCDEHGIMLIADEVQSGAGRTGTLF-AMEQMGVAPDLTTFAKSIAGGFPL 276 Query: 252 TGWKVGWVLGPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFPQ 311 G V G +M + + + A E + + + Q Sbjct: 277 AG-----VTGRAEVMDAVAPGGLGGTYAGNPIACVAALEVLKVFEQENLLQKA--NDLGQ 329 Query: 312 AMQRCRDHMIRSLQSVGLKPIIPQGSYFLITDISDFKRKMPDLPGAVDEPYDRRFVKWMI 371 ++ + +G + G+ I D PD + R Sbjct: 330 KLKDGLLAIAEKHPEIGD--VRGLGAMIAIELFEDGDHNKPDAKLTAEIVARAR------ 381 Query: 372 KNKGLVAIPVSIFYSVPHQKHFDHYIRFCFVKDEATLQAMDEKLRK 417 +KGL+ + + I ++A ++ E + + Sbjct: 382 -DKGLILL-------SCGPYYNVLRILVPLTIEDAQIRQGLEIISQ 419 >3N5M-A nrPDB Length = 452 Score = 33.6 bits (75), Expect = 0.18, Method: Composition-based stats. Identities = 18/148 (12%), Positives = 51/148 (34%), Gaps = 15/148 (10%) Query: 192 SREELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTIGSAGKTFSA 251 ++ ++ V CQ+H + I+DEV G + + + + + K ++ Sbjct: 234 PQDYMKAVHETCQKHGALLISDEVICGFGRTGK---AFGFMNYDVKPDII--TMAKGITS 288 Query: 252 TGWKVGWVLGPDHIMKHLRTVHQNSVF---HCPTQSQAAVAESFEREQLLFRQPSSYFVQ 308 + I + + + F + + AA A + + +++ Sbjct: 289 AYLPLSATAVKREIYEAFKGKGEYEFFRHINTFGGNPAACALALKNLEIIEN------EN 342 Query: 309 FPQAMQRCRDHMIRSL-QSVGLKPIIPQ 335 + + ++ L + +G P++ Sbjct: 343 LIERSAQMGSLLLEQLKEEIGEHPLVGD 370 >2ZUK-A nrPDB Length = 439 Score = 33.2 bits (74), Expect = 0.20, Method: Composition-based stats. Identities = 22/140 (15%), Positives = 43/140 (30%), Gaps = 8/140 (5%) Query: 90 PLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPI 149 R ++ G G + A + F + A + + P P Sbjct: 120 AYRAIVKATGRSGVI-----AFAGAYHGCTVGSMAFSGHSVQADAAKADGLILLPYPDPY 174 Query: 150 QNGELGSSSNWQLDP--MELAGKFTSRTKALVLNTPNNPLGKVFSRE-ELELVASLCQQH 206 + + + L +LA A + + G + + L A +C+ H Sbjct: 175 RPYRNDPTGDAILTLLTEKLAAVPAGSIGAAFIEPIQSDGGLIVPPDGFLRKFADICRAH 234 Query: 207 DVVCITDEVYQWMVYDGHQH 226 ++ + DEV + G H Sbjct: 235 GILVVCDEVKVGLARSGRLH 254 >2JIS-A nrPDB Length = 515 Score = 33.2 bits (74), Expect = 0.23, Method: Composition-based stats. Identities = 32/250 (12%), Positives = 75/250 (30%), Gaps = 31/250 (12%) Query: 194 EELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTIGSAGKTFSATG 253 + LE +A +CQ+H + D + V H + + + K + G Sbjct: 276 DPLEAIADVCQRHGLWLHVDAAWGGSVLLSQTHRHLLDGIQRADSV--AWNPHKLLA-AG 332 Query: 254 WKVGWVLGPD--HIMKHLRTVHQNSVFHCPTQSQAAV-----AESFEREQLLFRQPSSYF 306 + +L D +++K + +F A+ R + + Sbjct: 333 LQCSALLLQDTSNLLKRCHGSQASYLFQQDKFYDVALDTGDKVVQCGRRVDCLKLWLMWK 392 Query: 307 VQFPQAMQRCRD-------HMIRSLQS-VGLK-PIIPQGSYFLITDISDFKRKMPDLPGA 357 Q Q ++R D +++ ++ G + + P+ + R + P Sbjct: 393 AQGDQGLERRIDQAFVLARYLVEEMKKREGFELVMEPEFVNVCFWFVPPSLRGKQESPDY 452 Query: 358 VDEPYDRR--FVKWMIKNKGLVAIPVSIFYSVPHQKHFDHYIRFCFVKDE---ATLQAMD 412 + + M+K S+ ++ R A + + Sbjct: 453 HERLSKVAPVLKERMVKE-------GSMMIGYQPHGTRGNFFRVVVANSALTCADMDFLL 505 Query: 413 EKLRKWKVEL 422 +L + +L Sbjct: 506 NELERLGQDL 515 >1ORD-A nrPDB Length = 730 Score = 33.2 bits (74), Expect = 0.23, Method: Composition-based stats. Identities = 26/110 (23%), Positives = 38/110 (34%), Gaps = 2/110 (1%) Query: 66 TFGYPPLTKILASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFF 125 G + + A + + + + V G A T ALV GD V+ Sbjct: 164 ALGDLLIHEGPAVAAEKHAARVYNADKTYFVLGGSSNANNTVTSALVSNGDLVLFDRNNH 223 Query: 126 -DCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNW-QLDPMELAGKFTS 173 Y MAGGRPV++ P S++ + ELA K Sbjct: 224 KSVYNSALAMAGGRPVYLQTNRNPYGFIGGIYDSDFDEKKIRELAAKVDP 273 >3GJU-A nrPDB Length = 460 Score = 32.9 bits (73), Expect = 0.31, Method: Composition-based stats. Identities = 22/157 (14%), Positives = 41/157 (26%), Gaps = 30/157 (19%) Query: 62 QYTKTFGYPPLTKILASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVI-I 120 Y G P KI++ + G V G L A V+ Sbjct: 134 YYNNVLGRPEKKKIISRW-RGYHGSG--------VMTGSLTGLDLFHNAFDLPRAPVLHT 184 Query: 121 IEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVL 180 P++ +S + + P +A Sbjct: 185 EAPYY---------FRRTDRSMSEEQFSQHCADKLEEMILAEGPETIAAFIGEPILG--- 232 Query: 181 NTPNNPLGKVFSRE--ELELVASLCQQHDVVCITDEV 215 G + E + ++ +++DV+ + DEV Sbjct: 233 ------TGGIVPPPAGYWEKIQAVLKKYDVLLVADEV 263 >1EA9-C nrPDB Length = 583 Score = 32.5 bits (72), Expect = 0.32, Method: Composition-based stats. Identities = 7/47 (14%), Positives = 17/47 (36%), Gaps = 3/47 (6%) Query: 192 SREELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWER 238 ++ L+ + LC + + + D V+ G + E+ Sbjct: 217 DKDTLKKLVDLCHERGIRVLLDAVFNH---SGRTFPPFVDVLKNGEK 260 >5KR6-A nrPDB Length = 479 Score = 32.5 bits (72), Expect = 0.33, Method: Composition-based stats. Identities = 42/221 (19%), Positives = 74/221 (33%), Gaps = 20/221 (9%) Query: 123 PFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLD-PMELAGKF---TSRTKAL 178 P F + + P+ + P + S + + EL T A Sbjct: 187 PAFHNHFDLP----LEPIRHTTCPHYYRAPAGMSEAEFSRHCADELEKMILAEGPDTVAA 242 Query: 179 VLNTPNNPLGKVFSREE--LELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMW 236 + P G + E E + ++ ++D++ I DEV G S GM Sbjct: 243 FIGEPVMGTGGIVPPPEGYWEAIQAVLNKYDILLIADEVVCGFGRTGSMFGS--HHYGMK 300 Query: 237 ERTLTI--GSAGKTFSATGWKVG---WVLGPDHIMKHLRTVHQNSVFHCPTQSQAAVAE- 290 +T+ G +G VG W + ++ H + P + AA+A Sbjct: 301 PDLITVAKGLTSAYAPLSGVIVGEKVWKVLEQGSDQYGPIGHGWTYSGHPICAAAALANL 360 Query: 291 SFEREQLLFRQPSSYFVQFPQAMQRCR-DH-MIRSLQSVGL 329 + L + F Q M+ DH ++ ++ VGL Sbjct: 361 DIIERENLTGNAADTGAYFQQRMRETFGDHPLVGEVRGVGL 401 >6GWI-A nrPDB Length = 462 Score = 32.5 bits (72), Expect = 0.34, Method: Composition-based stats. Identities = 64/370 (17%), Positives = 107/370 (28%), Gaps = 46/370 (12%) Query: 31 VNLGQGFPDFPPPDFAVEAFQHAVSGDFMLNQYTKTFGYPPLTKILASFFGELLGQEIDP 90 VNLG G VEA + N + KT P + +L Sbjct: 59 VNLGYGR------RELVEAATAQLEQLPYYNTFFKTTHPPAVRLA-----EKLCDLAPAH 107 Query: 91 LRNVLVTVGGYGALFTAFQ------ALVDEGDE--VIIIEPFFDCYEPMTMMAGGRPVFV 142 + V T G A T + AL + D+ +I E + M GG Sbjct: 108 INRVFFTGSGSEANDTVLRMVRRYWALKGQPDKQWIIGRENAYHGSTLAGMSLGGMAPMH 167 Query: 143 SLKPGPIQNGELGSSSNWQLD-------------PMELAGKF----TSRTKALVLNTPNN 185 + + W + L K + A + Sbjct: 168 AQGGPCVPGIAHIRQPYWFGEGRDMSPEAFGQTCAEALEEKILELGEEKVAAFIAEPVQG 227 Query: 186 PLGKVFSRE-ELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTIGS 244 G + E V + ++D++ + DEV G S + G Sbjct: 228 AGGAIMPPESYWPAVKKVLAKYDILLVADEVICGFGRLGEWFGSQHYGLEPDLMPIAKGL 287 Query: 245 AGKTFSATGWKVGWVLGPDHIMKHLRTVHQNSVFHCPTQSQAAV--AESFEREQLLFRQP 302 + G VG + I + H + PT + A+ E E E ++ R Sbjct: 288 SSGYLPIGGVLVGDRVAETLIEEGGEFFHGFTYSGHPTCAAVALKNLELLEAEGVVDRVR 347 Query: 303 SSYFVQFPQAMQRCRDH-MIRSLQSVGLKPIIPQGSYFLITDISDFKRKMPDLPGAVDEP 361 + DH ++ +S+GL G+ L+ D ++ GA + Sbjct: 348 DDLGPYLAERWASLVDHPIVGEARSLGLM-----GALELVAD-KTTGQRFDKSLGAGNLC 401 Query: 362 YDRRFVKWMI 371 D F ++ Sbjct: 402 RDLCFANGLV 411 >5EAV-A nrPDB Length = 441 Score = 32.5 bits (72), Expect = 0.34, Method: Composition-based stats. Identities = 39/255 (15%), Positives = 84/255 (32%), Gaps = 21/255 (8%) Query: 162 LDPMEL----AGKFTSRTKALVLNTPNNPLGKVFSRE-ELELVASLCQQHDVVCITDEVY 216 +D ++ A + G + L+ LC+ +V+ I DE+ Sbjct: 201 IDYDDVGALEEALKDPNVAAFFVEPIQGEGGVNVPKPGYLKRAHELCRSKNVLLIVDEIQ 260 Query: 217 QWMVYDGHQHISIASLPGMWERTLTIGSAGKTFSATGWKVGWVLGPDHIMKHLRTVHQNS 276 + G + A + L +G K+ SA + V+G +M L+ S Sbjct: 261 TGLCRTG--RLLAADHDEVHPDILLLG---KSLSAGVVPISAVMGRADVMDVLKPGTHGS 315 Query: 277 VFHCPTQSQAAVAESFE--REQLLFRQPSSYFVQFPQAMQRCRDHMIRSLQSVGLKPIIP 334 F + A E+ +++ L + QF ++R + + + K I Sbjct: 316 TFGGNPLACAVAVEALTVLKDEKLADRAERLGAQFRDCLRRE---LYGKVPWI--KEIRG 370 Query: 335 QGSYFLITDISDFKRKMPDLPGAVDEPYDRRFVKWMIKNKGLVAIPVSIFYSVPHQKHFD 394 +G + + + D V + + + + + + IP + H+ Sbjct: 371 RG----LLNAVEVDSDAIDPNDVVMKLKENGILSKPTRGRVMRFIPPLVITDEEHRDATT 426 Query: 395 HYIRFCFVKDEATLQ 409 I+ +E + Sbjct: 427 RIIKSFLAVEEERKK 441 >4BQ0-A nrPDB Length = 448 Score = 32.1 bits (71), Expect = 0.41, Method: Composition-based stats. Identities = 38/198 (19%), Positives = 66/198 (33%), Gaps = 30/198 (15%) Query: 45 FAVEAFQHAVSGDFMLNQYTKTFGYP-PLTKILASFFGELLGQEIDPLRNVLVT-VGGYG 102 + + Q AV+ Y+ F Y PL+ LA LL E+ +V T G Sbjct: 67 HSRKEIQEAVARQLGTLDYSPGFQYGHPLSFQLAEKIAGLLPGEL---NHVFFTGSGSEC 123 Query: 103 ALFTAFQALV------DEGDEVIII-EPFFDCYEPMTMMAGG--------------RPVF 141 A + A +I + GG + Sbjct: 124 ADTSIKMARAYWRLKGQPQKTKLIGRARGYHGVNVAGTSLGGIGGNRKMFGQLMDVDHLP 183 Query: 142 VSLKPGPIQNGELGSSSNWQL--DPMELAGKFTSRTKALVLNTPNNPLGKVFSRE--ELE 197 +L+PG + + +L + ++L + A V+ P + V L+ Sbjct: 184 HTLQPGMAFTRGMAQTGGVELANELLKLIELHDASNIAAVIVEPMSGSAGVLVPPVGYLQ 243 Query: 198 LVASLCQQHDVVCITDEV 215 + +C QH+++ I DEV Sbjct: 244 RLREICDQHNILLIFDEV 261 >5KR3-A nrPDB Length = 479 Score = 32.1 bits (71), Expect = 0.46, Method: Composition-based stats. Identities = 26/133 (19%), Positives = 47/133 (35%), Gaps = 5/133 (3%) Query: 163 DPMELAGKFTSRTKALVLNTPNNPLGKVFSRE--ELELVASLCQQHDVVCITDEVYQWMV 220 + +L + + T A + P G + E + ++ ++HD++ I DEV Sbjct: 227 ELEKLIAREGADTIAAFIAEPVMGTGGIIPPPQGYWEAIQAVLRKHDILLIADEVVCGFG 286 Query: 221 YDGHQHISIASLPGMWERTLTIGSAGKTFSATGWKVG---WVLGPDHIMKHLRTVHQNSV 277 G + S T+ G +G VG W + +H H + Sbjct: 287 RLGSKMGSQHYGIKPDLITVAKGLTSAYAPLSGVIVGEKVWDVIEKGSQEHGPMGHGWTY 346 Query: 278 FHCPTQSQAAVAE 290 P + AA+A Sbjct: 347 SGHPICAAAALAN 359 >6GIO-D nrPDB Length = 439 Score = 32.1 bits (71), Expect = 0.53, Method: Composition-based stats. Identities = 8/27 (29%), Positives = 14/27 (51%) Query: 189 KVFSREELELVASLCQQHDVVCITDEV 215 V LE + C++H ++ + DEV Sbjct: 214 VVPPPAFLEALQDRCRKHGILVVVDEV 240 >2Z9W-A nrPDB Length = 392 Score = 31.7 bits (70), Expect = 0.54, Method: Composition-based stats. Identities = 22/152 (14%), Positives = 43/152 (28%), Gaps = 23/152 (15%) Query: 103 ALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQL 162 L A +L+ D V+ + G+ K E+ N + Sbjct: 71 GLEAAAASLISPDDVVL----------NLASGVYGKGFGYWAKRYSPHLLEIEVPYNEAI 120 Query: 163 DPMELAGKFT--SRTKALVLNTPNNPLGKVFSREELELVASLCQQHDVVCITDEVYQWMV 220 DP +A + + + P G + ++ + +L H I D V Sbjct: 121 DPQAVADMLKAHPEITVVSVCHHDTPSGTINP---IDAIGALVSAHGAYLIVDAV----- 172 Query: 221 YDGHQHISIASLPGMWERTLTIGSAGKTFSAT 252 + + P + + + K A Sbjct: 173 ---SSFGGMKTHPEDCKADIYVTGPNKCLGAP 201 >4WYG-A nrPDB Length = 457 Score = 31.7 bits (70), Expect = 0.68, Method: Composition-based stats. Identities = 17/122 (13%), Positives = 40/122 (32%), Gaps = 9/122 (7%) Query: 192 SREELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTIGSAGKTFSA 251 L + +C++++V+ I DE+ G A G+ + +G + Sbjct: 253 DPRYLHDLRDICRRYEVLLIFDEIATGFGRTGALFA--ADHAGVSPDIMCVGK-----AL 305 Query: 252 TG--WKVGWVLGPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQF 309 TG + L + + ++ H PT +A + + + + Sbjct: 306 TGGYLSLAATLCTADVAHTISAGAAGALMHGPTFMANPLACAVSVASVELLLGQDWRTRI 365 Query: 310 PQ 311 + Sbjct: 366 TE 367 >5KQW-A nrPDB Length = 479 Score = 31.7 bits (70), Expect = 0.69, Method: Composition-based stats. Identities = 27/135 (20%), Positives = 47/135 (34%), Gaps = 9/135 (6%) Query: 163 DPMELAGKFTSRTKALVLNTPNNPLGKVFSRE--ELELVASLCQQHDVVCITDEVYQWMV 220 + +L T A + P G + E + ++ ++D++ I DEV Sbjct: 227 ELEKLILAEGPDTVAAFIGEPVMGTGGIIPPPQGYWEAIQAVLNKYDILLIADEVVCGFG 286 Query: 221 YDGHQHISIASLPGMWERTLTI--GSAGKTFSATGWKVG---WVLGPDHIMKHLRTVHQN 275 G + S GM +T+ G +G VG W + +H H Sbjct: 287 RLGSKMGS--QHYGMKPDLITVAKGLTSAYAPLSGVIVGEKVWDVIEKGSQEHGPMGHGW 344 Query: 276 SVFHCPTQSQAAVAE 290 + P + AA+A Sbjct: 345 TYSGHPICAAAALAN 359 >4IW7-A nrPDB Length = 399 Score = 31.3 bits (69), Expect = 0.71, Method: Composition-based stats. Identities = 35/226 (15%), Positives = 70/226 (30%), Gaps = 33/226 (14%) Query: 195 ELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTI-GSAGKTFSATG 253 +L+ +A + + I DE + + V + +I S ++ L GK F G Sbjct: 194 QLDKLAKITPEK---LIVDEAHSFGVLGKNGRGAINSFRISYKNCLICVFPLGKAFGGVG 250 Query: 254 WKVGWVLGPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFPQAM 313 V + I ++L +N ++ A+ + L+ + + Sbjct: 251 ---AVVCTTEAIAEYLIQFARNYIYTT------ALPPMILKAALIQLKNLENVNDNRARL 301 Query: 314 QRCRDHMIRSLQSVGLKPIIPQGSYFLITDISDFKRKMPDLPGAVDEPYDRRFVKWMIKN 373 Q+ + L+ + D+S + + D+ F +I Sbjct: 302 QQNITFFNELCDAKDLE--------LVSKDLSPIRSIQLNNANLAIRLKDKLFENKII-- 351 Query: 374 KGLVAIPVSIFYSVPHQKHFDHYIRFCFVKDE--ATLQAMDEKLRK 417 VS F P +RF + +Q E + K Sbjct: 352 -------VSCF-RYPTVPKDQAILRFSLHSNNTFDQIQQALEIISK 389 >6IO1-A nrPDB Length = 451 Score = 31.3 bits (69), Expect = 0.77, Method: Composition-based stats. Identities = 27/184 (14%), Positives = 50/184 (27%), Gaps = 9/184 (4%) Query: 188 GKVFSRE-ELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTIGSAG 246 G V + +A++ +++ ++ I DEV G T G Sbjct: 234 GVVVPPDGYWPAIAAVLRKYGILLILDEVITGFGRTGTLFGMQQYGVQPDIVTFAKGITS 293 Query: 247 KTFSATGWKVGWVLGPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYF 306 G VG + V + + AVA L R + Sbjct: 294 GYVPLGG--VGVSDEIAETLASADRVFMHGFTYSGHPVACAVALRNLDILLAERLWENAA 351 Query: 307 VQFPQAMQRCRDHMIRSLQS-VGLKPIIPQGSYFLITDISDFKRKMPDLPGAVDEPYDRR 365 +Q ++ L+ + + +G L+ + D K P P Sbjct: 352 ASGAYLLQE-----LKRLEERPYVGEVRGKGLMLLVEVVRDKASKEKFPPEFKLGPKLEA 406 Query: 366 FVKW 369 + Sbjct: 407 ATRR 410 >3DOR-A nrPDB Length = 583 Score = 31.3 bits (69), Expect = 0.78, Method: Composition-based stats. Identities = 22/104 (21%), Positives = 41/104 (39%), Gaps = 17/104 (16%) Query: 125 FDCYEPMTMMAGGRPVFVSLKPGP------IQNGELGSSSNWQLDPMELAGKFTSRTKAL 178 F Y G+ V P +++ + W+ + ++ F+S T+AL Sbjct: 276 FRAYISSVTDGDGKSHKVGFLRIPTYSWQDMEDFDPSGPPPWE-EFAKIIQVFSSNTEAL 334 Query: 179 VLNTPNNPLGKVFSREELELVASLCQ-------QHDVVCITDEV 215 +++ NNP G V L + S+ +H ++ DEV Sbjct: 335 IIDQTNNPGGSVL---YLYALLSMLTDRPLELPKHRMILTQDEV 375 >1W3H-A nrPDB Length = 359 Score = 31.3 bits (69), Expect = 0.88, Method: Composition-based stats. Identities = 22/112 (19%), Positives = 34/112 (30%), Gaps = 30/112 (26%) Query: 40 FPPPDFAVEAFQHAVSGDFMLNQYTKTFGYPPLTKILASFFGELLGQEIDPLRNVLVTVG 99 F P++ EAF+ A + D EL + + N G Sbjct: 166 FGGPEYIDEAFRRARAADPT---------------------AELYYNDFNTEEN-----G 199 Query: 100 G-YGALFTAFQALVDEG---DEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPG 147 AL Q L++ G D V + Y + + V+L P Sbjct: 200 AKTTALVNLVQRLLNNGVPIDGVGFQMHVMNDYPSIANIRQAMQKIVALSPT 251 >4LNN-A nrPDB Length = 443 Score = 30.9 bits (68), Expect = 0.93, Method: Composition-based stats. Identities = 13/98 (13%), Positives = 27/98 (27%), Gaps = 9/98 (9%) Query: 155 GSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQQHDVVCITDE 214 + + + P +R + NP G F + + + ++ + D Sbjct: 71 PDLNTFVIFPWTAEKGKVAR----FICDIYNPDGTPFEGDPRNNLKRILKE-----MEDL 121 Query: 215 VYQWMVYDGHQHISIASLPGMWERTLTIGSAGKTFSAT 252 + + L E TL + G F Sbjct: 122 GFSDFNLGPEPEFFLFKLDEKGEPTLELNDKGGYFDLA 159 >1J0H-A nrPDB Length = 588 Score = 30.9 bits (68), Expect = 0.96, Method: Composition-based stats. Identities = 6/35 (17%), Positives = 14/35 (40%) Query: 192 SREELELVASLCQQHDVVCITDEVYQWMVYDGHQH 226 +E L+ + C + + + D V+ Y+ Sbjct: 221 DKETLKTLIDRCHEKGIRVMLDAVFNHCGYEFAPF 255 >5KQT-A nrPDB Length = 479 Score = 30.9 bits (68), Expect = 1.0, Method: Composition-based stats. Identities = 31/180 (17%), Positives = 55/180 (30%), Gaps = 17/180 (9%) Query: 163 DPMELAGKFTSRTKALVLNTPNNPLGKVF--SREELELVASLCQQHDVVCITDEVYQWMV 220 + L T A + P G + + E + ++ ++DV+ I DEV Sbjct: 227 ELENLILAEGPDTVAAFIGEPVMGTGGIIVPPKGYWEAIQAVLAKYDVLLIADEVVCAFG 286 Query: 221 YDGHQHISIASLPGMWERTLTIGSAGKTFSATGWKVG---WVLGPDHIMKHLRTVHQNSV 277 G + S T G + VG W + + H + Sbjct: 287 RLGDKMGSQRHAMRPDLITTAKGLTSAYAPLSAVIVGEKVWDVIDSASTREGAMGHGWTY 346 Query: 278 FHCPTQSQAAV------------AESFEREQLLFRQPSSYFVQFPQAMQRCRDHMIRSLQ 325 P + AA+ A + + L +Q F P + D M+ +L+ Sbjct: 347 SGHPICAAAALANLDILERENITANAADVGGYLNQQLRQAFEGHPLVGEVRGDGMLAALE 406 >4UHN-A nrPDB Length = 468 Score = 30.9 bits (68), Expect = 1.2, Method: Composition-based stats. Identities = 34/198 (17%), Positives = 64/198 (32%), Gaps = 30/198 (15%) Query: 45 FAVEAFQHAVSGDFMLNQYTKTFGYP-PLTKILASFFGELLGQEIDPLRNVLVT-VGGYG 102 + + AV+ Y+ F Y PL+ LA ++ +D +V T G Sbjct: 87 HSRKEIADAVAKQIGTLDYSPGFQYGHPLSFQLAEKIAQMTPGTLD---HVFFTGSGSEC 143 Query: 103 ALFTAFQALV------DEGDEVIII-EPFFDCYEPMTMMAGG--------------RPVF 141 A + A +I + GG + Sbjct: 144 ADTSIKMARAYWRIKGQAQKTKLIGRARGYHGVNVAGTSLGGIGGNRKMFGPLMDVDHLP 203 Query: 142 VSLKPGPIQNGELGSSSNWQL--DPMELAGKFTSRTKALVLNTPNNPLGKVF--SREELE 197 +L+PG + +L + ++L + A V+ P + V + L+ Sbjct: 204 HTLQPGMAFTKGAAETGGVELANELLKLIELHDASNIAAVIVEPMSGSAGVIVPPKGYLQ 263 Query: 198 LVASLCQQHDVVCITDEV 215 + +C +D++ I DEV Sbjct: 264 RLREICDANDILLIFDEV 281 >1SMA-A nrPDB Length = 588 Score = 30.6 bits (67), Expect = 1.3, Method: Composition-based stats. Identities = 6/35 (17%), Positives = 14/35 (40%) Query: 192 SREELELVASLCQQHDVVCITDEVYQWMVYDGHQH 226 +E L+ + C + + + D V+ Y+ Sbjct: 221 DKETLKTLVKRCHEKGIRVMLDAVFNHCGYEFAPF 255 >1SPI-A nrPDB Length = 358 Score = 30.6 bits (67), Expect = 1.3, Method: Composition-based stats. Identities = 11/67 (16%), Positives = 25/67 (37%) Query: 335 QGSYFLITDISDFKRKMPDLPGAVDEPYDRRFVKWMIKNKGLVAIPVSIFYSVPHQKHFD 394 +G+Y + D PG +PY R++ ++ + + I+ K + Sbjct: 239 EGNYKMWPDKLKKYMDDLKEPGESQKPYSSRYIGSLVGDFHRTLLYGGIYGYPRDAKSKN 298 Query: 395 HYIRFCF 401 +R + Sbjct: 299 GKLRLLY 305 >3FXW-A nrPDB Length = 336 Score = 30.6 bits (67), Expect = 1.4, Method: Composition-based stats. Identities = 14/127 (11%), Positives = 31/127 (24%), Gaps = 6/127 (4%) Query: 85 GQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVSL 144 +++ P + + L E + + P + Y + G S Sbjct: 151 HRDVKPENLLYTSKEKDAVLKLTDFGFAKETTQNALQTPCYTPYYVAPEVLGPEKYDKSC 210 Query: 145 KPGPIQNGELGSSSNWQLDPMELAGKFTS----RTKALVLNTPNNPLGKVFSREELELVA 200 + + + R + P NP S + + + Sbjct: 211 DMWSLGVIMYILLCGFPPFYSNTGQAISPGMKRRIRLGQYGFP-NPEWSEVSEDA-KQLI 268 Query: 201 SLCQQHD 207 L + D Sbjct: 269 RLLLKTD 275 >5IZ1-A nrPDB Length = 337 Score = 30.6 bits (67), Expect = 1.4, Method: Composition-based stats. Identities = 12/67 (17%), Positives = 25/67 (37%) Query: 335 QGSYFLITDISDFKRKMPDLPGAVDEPYDRRFVKWMIKNKGLVAIPVSIFYSVPHQKHFD 394 +G+Y L D PG +PY R++ ++ + + I+ K + Sbjct: 218 EGNYALWDDKLKKYVDSLKDPGPSGKPYSARYIGSLVGDFHRTMLYGGIYGYPRDSKSKN 277 Query: 395 HYIRFCF 401 +R + Sbjct: 278 GKLRLLY 284 >4OKD-A nrPDB Length = 840 Score = 30.6 bits (67), Expect = 1.5, Method: Composition-based stats. Identities = 12/63 (19%), Positives = 27/63 (42%), Gaps = 2/63 (3%) Query: 192 SREELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTIGSAGK-TFS 250 S +E + + C + + I D V+ +G++ S G+ R + + G ++ Sbjct: 321 SCDEFKQLVKECHRRGIEVILDVVFNHTA-EGNERGPTISFRGLDNRVYYMLAPGGEYYN 379 Query: 251 ATG 253 +G Sbjct: 380 YSG 382 >5JZX-A nrPDB Length = 405 Score = 30.2 bits (66), Expect = 1.9, Method: Composition-based stats. Identities = 13/83 (15%), Positives = 19/83 (22%), Gaps = 2/83 (2%) Query: 38 PDFPPPDFAVEAFQHAVSGDFMLNQYTKTFGYPPLTKILASFFGELLGQEIDPLRNVLVT 97 P +P PD A V Y G P V + Sbjct: 321 PHYPAPDGVKLAAGWLVERAGFGKGY-PDAGAAPCRLSTKHALALTNRGGATAEDVVTLA 379 Query: 98 VGGYGALFTAFQALVDEGDEVII 120 + F + + V+I Sbjct: 380 RAVRDGVHDVFGITLKP-EPVLI 401 >4BA4-A nrPDB Length = 459 Score = 29.8 bits (65), Expect = 2.2, Method: Composition-based stats. Identities = 40/213 (18%), Positives = 66/213 (30%), Gaps = 41/213 (19%) Query: 31 VNLGQGFPDFPPPDFAVEAFQHAVSGDFMLNQYTKTFGYPPLTKILASFFGELLGQEIDP 90 VN+G G DF EA + + N + KT +P + + L+S E+ D Sbjct: 62 VNVGYGRKDF------AEAARRQMEELPFYNTFFKTT-HPAVVE-LSSLLAEVTPAGFD- 112 Query: 91 LRNVLVTVGGYGALFTAFQALV-------DEGDEVIIIEPFFDCYEPMT---MMAGGRPV 140 V T G ++ T + + + +I ++ Y T GG Sbjct: 113 --RVFYTNSGSESVDTMIRMVRRYWDVQGKPEKKTLIGR--WNGYHGSTIGGASLGGMKY 168 Query: 141 FVSLKPGPIQNGELGSSSNW-------QLDPMELAGKFTSRTKAL---------VLNTPN 184 PI W D + K L + P Sbjct: 169 MHEQGDLPIPGMAHIEQPWWYKHGKDMTPDEFGVVAARWLEEKILEIGADKVAAFVGEPI 228 Query: 185 NPLGKVF--SREELELVASLCQQHDVVCITDEV 215 G V + +C+++DV+ + DEV Sbjct: 229 QGAGGVIVPPATYWPEIERICRKYDVLLVADEV 261 >5KQU-A nrPDB Length = 479 Score = 29.8 bits (65), Expect = 2.3, Method: Composition-based stats. Identities = 16/96 (16%), Positives = 33/96 (34%), Gaps = 4/96 (4%) Query: 123 PFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLD-PMELAGKFTSRTKALVLN 181 P F + + + G + + + + D +L T A + Sbjct: 187 PSFHQHFDLP-VEGIKHTVCPHWYKAPAGMDEAAFVRYCADELEKLILAEGPDTVAAFIG 245 Query: 182 TPNNPLGKVF--SREELELVASLCQQHDVVCITDEV 215 P G + + E + ++ ++DV+ I DEV Sbjct: 246 EPVMGTGGIIVPPKGYWEAIQAVLNKYDVLLIADEV 281 >5KR5-A nrPDB Length = 479 Score = 29.8 bits (65), Expect = 2.4, Method: Composition-based stats. Identities = 12/55 (21%), Positives = 25/55 (45%), Gaps = 2/55 (3%) Query: 163 DPMELAGKFTSRTKALVLNTPNNPLGKVFSRE--ELELVASLCQQHDVVCITDEV 215 + +L + + T A + P G + E + ++ ++HD++ I DEV Sbjct: 227 ELEKLIAREGADTIAAFIAEPVMGTGGIVPPPQGYWEAIQAVLRKHDILLIADEV 281 >1OAT-A nrPDB Length = 439 Score = 29.4 bits (64), Expect = 2.8, Method: Composition-based stats. Identities = 16/63 (25%), Positives = 21/63 (33%), Gaps = 2/63 (3%) Query: 163 DPMELAGKFTSRTKALVLNTP-NNPLGKVF-SREELELVASLCQQHDVVCITDEVYQWMV 220 D L A + P G V L V LC +H V+ I DE+ + Sbjct: 211 DLPALERALQDPNVAAFMVEPIQGEAGVVVPDPGYLMGVRELCTRHQVLFIADEIQTGLA 270 Query: 221 YDG 223 G Sbjct: 271 RTG 273 >2E8Y-A nrPDB Length = 718 Score = 29.4 bits (64), Expect = 3.1, Method: Composition-based stats. Identities = 15/66 (22%), Positives = 27/66 (40%), Gaps = 4/66 (6%) Query: 181 NTPNNPLGKVFSREELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTL 240 + P++P + EL+ + + QH + I D V+ VY ++PG + R Sbjct: 306 SNPHDPQ---TRKTELKQMINTLHQHGLRVILDVVFNH-VYKRENSPFEKTVPGYFFRHD 361 Query: 241 TIGSAG 246 G Sbjct: 362 ECGKPS 367 >1WA5-C nrPDB Length = 960 Score = 29.4 bits (64), Expect = 3.1, Method: Composition-based stats. Identities = 6/34 (17%), Positives = 17/34 (50%) Query: 182 TPNNPLGKVFSREELELVASLCQQHDVVCITDEV 215 P+NP ++ E + + + Q+ ++ + D + Sbjct: 609 NPSNPRFTHYTFESIGAILNYTQRQNLPLLVDSM 642 >5OQM-k nrPDB Length = 157 Score = 29.4 bits (64), Expect = 3.1, Method: Composition-based stats. Identities = 14/59 (23%), Positives = 22/59 (37%), Gaps = 5/59 (8%) Query: 39 DFPPPDFAVEAFQHAVSGDFMLNQY--TKTFGYPPLTKILASFFGELLGQEIDPLRNVL 95 D PD F A+ NQY K G L LA + + +P+ +++ Sbjct: 89 DGRNPDIYTREFVEAIRRS---NQYQRGKMHGLKQLRDSLADKIVDEFPELKEPVEDII 144 >4RIT-B nrPDB Length = 486 Score = 29.4 bits (64), Expect = 3.4, Method: Composition-based stats. Identities = 21/156 (13%), Positives = 49/156 (31%), Gaps = 13/156 (8%) Query: 95 LVTVGGYGALFTAFQA-------LVDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPG 147 ++T GG A A V+ G + P + + + L G Sbjct: 149 VLTSGGSLANLQALAVARNVAFDSVEPGITGLAQRPV--IFASEAAHTSLQKAAMLLGLG 206 Query: 148 PIQNGELGSSSNWQLDPMELAGKFTSRTKA---LVLNTPNNPLGKVFSREELELVASLCQ 204 + ++++ ++DP +L + A + + L + ++ + Sbjct: 207 TAAVIPVRATADSRMDPEDLRARIDQARGAGQHPFCVVATAGTTTTGNIDPLAEIGAIAR 266 Query: 205 QHDVVCITDEVYQW-MVYDGHQHISIASLPGMWERT 239 +H + D Y +V+ +A + T Sbjct: 267 EHGLWFHVDAAYGGALVFSERHRWRLAGIEQADSIT 302 >1V3M-A nrPDB Length = 686 Score = 29.4 bits (64), Expect = 3.5, Method: Composition-based stats. Identities = 8/63 (12%), Positives = 18/63 (28%), Gaps = 2/63 (3%) Query: 184 NNPLGKVFSREELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTIG 243 NP ++ + + H++ I D S A +++ +G Sbjct: 108 TNPAYGTM--QDFKNLIDTAHAHNIKVIIDFAPNHTSPASSDDPSFAENGRLYDNGNLLG 165 Query: 244 SAG 246 Sbjct: 166 GYT 168 >3A8U-X nrPDB Length = 449 Score = 28.6 bits (62), Expect = 4.7, Method: Composition-based stats. Identities = 9/29 (31%), Positives = 16/29 (55%), Gaps = 1/29 (3%) Query: 188 GKVFSRE-ELELVASLCQQHDVVCITDEV 215 G + E L+ +C QH+++ + DEV Sbjct: 233 GVLVPPEGYLKRNREICNQHNILLVFDEV 261 >2D3T-A nrPDB Length = 715 Score = 28.6 bits (62), Expect = 5.8, Method: Composition-based stats. Identities = 17/76 (22%), Positives = 31/76 (40%), Gaps = 1/76 (1%) Query: 3 KQLQARRLDGIDYNPWVEFVKLASEHDVVNLGQGFPDFPPPDFAVEAFQHAVSGDFMLNQ 62 K + +L+ + N + + + V GQ P++P P A++ Q A + Sbjct: 213 KAKRQPKLEKLKLNAIEQMMAFETAKGFVA-GQAGPNYPAPVEAIKTIQKAANFGRDKAL 271 Query: 63 YTKTFGYPPLTKILAS 78 + G+ L K AS Sbjct: 272 EVEAAGFAKLAKTSAS 287 >4ATY-A nrPDB Length = 349 Score = 27.9 bits (60), Expect = 9.8, Method: Composition-based stats. Identities = 8/32 (25%), Positives = 13/32 (40%) Query: 31 VNLGQGFPDFPPPDFAVEAFQHAVSGDFMLNQ 62 V L G P+ P+ AV+A + + Sbjct: 11 VALAIGDPNGIGPEIAVKAAAQMARDERSEHG 42 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.307 0.122 0.305 Lambda K H 0.267 0.0375 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 14,615,828 Number of Sequences: 36641 Number of extensions: 566064 Number of successful extensions: 2625 Number of sequences better than 10.0: 266 Number of HSP's better than 10.0 without gapping: 240 Number of HSP's successfully gapped in prelim test: 128 Number of HSP's that attempted gapping in prelim test: 1824 Number of HSP's gapped (non-prelim): 384 length of query: 422 length of database: 10,336,785 effective HSP length: 100 effective length of query: 322 effective length of database: 6,672,685 effective search space: 2148604570 effective search space used: 2148604570 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 60 (27.8 bits)