BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q16772 (222 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 2VCV-A nrPDB 451 e-128 1PL2-A nrPDB 404 e-113 2VCT-A nrPDB 399 e-112 3I6A-A nrPDB 388 e-108 5LCZ-A nrPDB 345 7e-96 1F3B-A nrPDB 342 8e-95 1EV4-A nrPDB 324 2e-89 1VF1-A nrPDB 286 3e-78 1B48-A nrPDB 284 2e-77 1GUL-A nrPDB 259 6e-70 1TU7-A nrPDB 96 1e-20 2GSR-A nrPDB 96 2e-20 2AAW-A nrPDB 94 6e-20 5D73-A nrPDB 92 2e-19 4Q5R-A nrPDB 87 5e-18 18GS-A nrPDB 87 6e-18 4Q5F-A nrPDB 86 1e-17 2GLR-A nrPDB 86 1e-17 1ZL9-A nrPDB 83 9e-17 1GSQ-A nrPDB 82 2e-16 1YQ1-A nrPDB 79 1e-15 5AN1-A nrPDB 79 1e-15 3KXO-A nrPDB 72 2e-13 4Q5Q-A nrPDB 71 5e-13 2FHE-A nrPDB 70 8e-13 5Y9Z-A nrPDB 69 2e-12 2WRT-A nrPDB 68 3e-12 2HNL-A nrPDB 66 1e-11 2WDU-A nrPDB 66 1e-11 1U3I-A nrPDB 63 9e-11 2CZ2-A nrPDB 63 1e-10 2CA8-A nrPDB 62 2e-10 3GTU-B nrPDB 60 9e-10 1HNA-A nrPDB 58 4e-09 1FHE-A nrPDB 57 5e-09 1B4P-A nrPDB 57 8e-09 5F07-A nrPDB 57 9e-09 1XWK-A nrPDB 55 2e-08 1DUG-A nrPDB 55 3e-08 5FWG-A nrPDB 55 3e-08 1B8X-A nrPDB 55 3e-08 1BG5-A nrPDB 55 3e-08 4PNG-A nrPDB 55 3e-08 1FW1-A nrPDB 55 3e-08 4GTU-A nrPDB 53 8e-08 4YH2-A nrPDB 53 1e-07 1M0U-A nrPDB 52 2e-07 5F06-A nrPDB 50 8e-07 2DC5-A nrPDB 49 1e-06 4WR5-A nrPDB 49 1e-06 4RI7-A nrPDB 44 8e-05 1GSU-A nrPDB 43 1e-04 3VWX-A nrPDB 42 3e-04 5F0G-A nrPDB 41 3e-04 3LSZ-A nrPDB 39 0.002 1F2E-A nrPDB 39 0.002 5EY6-A nrPDB 39 0.002 3M8N-A nrPDB 38 0.004 1PN9-A nrPDB 36 0.014 1AW9-A nrPDB 36 0.015 1AXD-A nrPDB 35 0.017 2GDR-A nrPDB 35 0.019 3MAK-A nrPDB 34 0.056 3GH6-A nrPDB 33 0.086 5A5K-A nrPDB 33 0.095 3IBH-A nrPDB 33 0.095 1JLV-A nrPDB 33 0.11 6F05-A nrPDB 33 0.14 5LOL-A nrPDB 32 0.17 3M3M-A nrPDB 32 0.19 3UBL-A nrPDB 32 0.21 3PPU-A nrPDB 32 0.21 4FQU-A nrPDB 32 0.26 3LG6-A nrPDB 31 0.34 5WTZ-A nrPDB 31 0.42 4G0L-A nrPDB 30 0.98 6GCB-A nrPDB 30 1.2 6FFY-A nrPDB 29 1.3 6GC9-A nrPDB 29 1.5 5ELG-A nrPDB 29 1.8 5F05-A nrPDB 28 2.4 2C3Q-A nrPDB 28 2.8 6D84-M nrPDB 28 3.9 5D9W-A nrPDB 28 4.3 5DXT-A nrPDB 27 4.7 4UY5-A nrPDB 27 4.8 3AYF-A nrPDB 27 5.4 3FD5-A nrPDB 27 5.6 5UDD-A nrPDB 27 7.8 2IL3-A nrPDB 27 7.9 1G6W-A nrPDB 27 8.0 >2VCV-A nrPDB Length = 222 Score = 451 bits (1161), Expect = e-128, Method: Compositional matrix adjust. Identities = 222/222 (100%), Positives = 222/222 (100%) Query: 1 MAGKPKLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQVPMVEI 60 MAGKPKLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQVPMVEI Sbjct: 1 MAGKPKLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQVPMVEI 60 Query: 61 DGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAK 120 DGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAK Sbjct: 61 DGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAK 120 Query: 121 IALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLISNFPL 180 IALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLISNFPL Sbjct: 121 IALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLISNFPL 180 Query: 181 LKALKTRISNLPTVKKFLQPGSPRKPPADAKALEEARKIFRF 222 LKALKTRISNLPTVKKFLQPGSPRKPPADAKALEEARKIFRF Sbjct: 181 LKALKTRISNLPTVKKFLQPGSPRKPPADAKALEEARKIFRF 222 >1PL2-A nrPDB Length = 222 Score = 404 bits (1038), Expect = e-113, Method: Compositional matrix adjust. Identities = 200/222 (90%), Positives = 207/222 (93%) Query: 1 MAGKPKLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQVPMVEI 60 MA KPKLHYFN RGRME RWLLAAAGVEFEEKFI SAEDL KLRNDG LMFQQVPMVEI Sbjct: 1 MAEKPKLHYFNARGRMESTRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEI 60 Query: 61 DGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAK 120 DGMKLVQ RAILNYIASKYNLYGKDIKERALIDMY EG+ADL EMILLLP+C PEEKDAK Sbjct: 61 DGMKLVQERAILNYIASKYNLYGKDIKERALIDMYIEGIADLGEMILLLPVCPPEEKDAK 120 Query: 121 IALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLISNFPL 180 +ALIKEK K+RYFPAFEKVL+SHGQDYLVGNKLSRADI LVELLYYVEELDSSLIS+FPL Sbjct: 121 LALIKEKIKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPL 180 Query: 181 LKALKTRISNLPTVKKFLQPGSPRKPPADAKALEEARKIFRF 222 LKALKTRISNLPTVKKFLQPGSPRKPP D K+LEEARKIFRF Sbjct: 181 LKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEEARKIFRF 222 >2VCT-A nrPDB Length = 222 Score = 399 bits (1026), Expect = e-112, Method: Compositional matrix adjust. Identities = 197/222 (88%), Positives = 208/222 (93%) Query: 1 MAGKPKLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQVPMVEI 60 MA KPKLHY N RGRME IRWLLAAAGVEFEEKFI SAEDL KLRNDG LMFQQVPMVEI Sbjct: 1 MAEKPKLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEI 60 Query: 61 DGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAK 120 DGMKLVQTRAILNYIASKYNLYGKDIKE+ALIDMY EG+ADL EMILLLP +PEE+DAK Sbjct: 61 DGMKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFTQPEEQDAK 120 Query: 121 IALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLISNFPL 180 +ALI+EKTK+RYFPAFEKVL+SHGQDYLVGNKLSRADI LVELLYYVEELDSSLIS+FPL Sbjct: 121 LALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPL 180 Query: 181 LKALKTRISNLPTVKKFLQPGSPRKPPADAKALEEARKIFRF 222 LKALKTRISNLPTVKKFLQPGSPRKPP D K+LEE+RKIFRF Sbjct: 181 LKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEESRKIFRF 222 >3I6A-A nrPDB Length = 222 Score = 388 bits (997), Expect = e-108, Method: Compositional matrix adjust. Identities = 192/221 (86%), Positives = 200/221 (90%) Query: 1 MAGKPKLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQVPMVEI 60 MA KPKLHYFNGRGRME RWLLAAAGVEFEEKFI SAEDL KLRNDG LMFQQVPMVEI Sbjct: 1 MAEKPKLHYFNGRGRMESTRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEI 60 Query: 61 DGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAK 120 DGMKLVQTRAILNYIASKYNLYGKDIKERALIDMY EG+ADL EMI++LP C PEEKDAK Sbjct: 61 DGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYIEGIADLGEMIIMLPFCPPEEKDAK 120 Query: 121 IALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLISNFPL 180 +ALIKEK K+RYFPAFEKVL+SHGQDYLVGNKLSRADI LVELLYYVEELDSSLIS+FPL Sbjct: 121 LALIKEKIKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPL 180 Query: 181 LKALKTRISNLPTVKKFLQPGSPRKPPADAKALEEARKIFR 221 LKALKTRISNLPTVKKFLQPGSPRKPP D + IFR Sbjct: 181 LKALKTRISNLPTVKKFLQPGSPRKPPPDEIYVRTVYNIFR 221 >5LCZ-A nrPDB Length = 222 Score = 345 bits (886), Expect = 7e-96, Method: Compositional matrix adjust. Identities = 174/222 (78%), Positives = 197/222 (88%) Query: 1 MAGKPKLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQVPMVEI 60 MA KPKLHYFN RGRME RWLLAAAGVEFEEKFI SAEDL KLRNDG LMFQQVPMVEI Sbjct: 1 MAEKPKLHYFNARGRMESTRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEI 60 Query: 61 DGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAK 120 DGMKLVQTRAILNYIASKYNLYGKD+KERALIDMY+EG+ DL EMI+ L +C P++++AK Sbjct: 61 DGMKLVQTRAILNYIASKYNLYGKDMKERALIDMYSEGILDLTEMIIQLVICPPDQREAK 120 Query: 121 IALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLISNFPL 180 AL K++TK+RY PAFEKVL+SHGQDYLVGN+L+R DI L+ELL YVEE D+SL+++FPL Sbjct: 121 TALAKDRTKNRYLPAFEKVLKSHGQDYLVGNRLTRVDIHLLELLLYVEEFDASLLTSFPL 180 Query: 181 LKALKTRISNLPTVKKFLQPGSPRKPPADAKALEEARKIFRF 222 LKA K+RIS+LP VKKFLQPGS RKP DAK +EEARKIFRF Sbjct: 181 LKAFKSRISSLPNVKKFLQPGSQRKPAMDAKQIEEARKIFRF 222 >1F3B-A nrPDB Length = 222 Score = 342 bits (877), Expect = 8e-95, Method: Compositional matrix adjust. Identities = 164/221 (74%), Positives = 191/221 (86%) Query: 2 AGKPKLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQVPMVEID 61 AGKP LHYFN RGRME IRWLLAAAGVEFEEKFI S EDL KL+ DG+LMF QVPMVEID Sbjct: 1 AGKPVLHYFNARGRMECIRWLLAAAGVEFEEKFIQSPEDLEKLKKDGNLMFDQVPMVEID 60 Query: 62 GMKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAKI 121 GMKL QTRAILNYIA+KY+LYGKD+KERALIDMY+EG+ DL EMI L LC P++++AK Sbjct: 61 GMKLAQTRAILNYIATKYDLYGKDMKERALIDMYSEGILDLTEMIGQLVLCPPDQREAKT 120 Query: 122 ALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLISNFPLL 181 AL K++TK+RY PAFEKVL+SHGQDYLVGN+L+R DI L+E+L YVEE D+SL++ FPLL Sbjct: 121 ALAKDRTKNRYLPAFEKVLKSHGQDYLVGNRLTRVDIHLLEVLLYVEEFDASLLTPFPLL 180 Query: 182 KALKTRISNLPTVKKFLQPGSPRKPPADAKALEEARKIFRF 222 KA K+RIS+LP VKKFLQPGS RKPP DAK ++EARK F+ Sbjct: 181 KAFKSRISSLPNVKKFLQPGSQRKPPMDAKQIQEARKAFKI 221 >1EV4-A nrPDB Length = 221 Score = 324 bits (830), Expect = 2e-89, Method: Compositional matrix adjust. Identities = 164/221 (74%), Positives = 194/221 (87%) Query: 2 AGKPKLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQVPMVEID 61 +GKP LHYFN RGRME IR+LLAAAGVEF+EKFI S EDL KL+ DG+LMF QVPMVEID Sbjct: 1 SGKPVLHYFNARGRMECIRFLLAAAGVEFDEKFIQSPEDLEKLKKDGNLMFDQVPMVEID 60 Query: 62 GMKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAKI 121 GMKL QTRAILNYIA+KY+LYGKD+KERALIDMY+EG+ DL EMI+ L +C P++K+AK Sbjct: 61 GMKLAQTRAILNYIATKYDLYGKDMKERALIDMYSEGILDLTEMIMQLVICPPDQKEAKT 120 Query: 122 ALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLISNFPLL 181 AL K++TK+RY PAFEKVL+SHGQDYLVGNKL+R DI L+ELL YVEE D+SL+++FPLL Sbjct: 121 ALAKDRTKNRYLPAFEKVLKSHGQDYLVGNKLTRVDIHLLELLLYVEEFDASLLTSFPLL 180 Query: 182 KALKTRISNLPTVKKFLQPGSPRKPPADAKALEEARKIFRF 222 KA K+RIS+LP VKKFLQPGS RK P DAK +EEARKI++F Sbjct: 181 KAFKSRISSLPNVKKFLQPGSQRKLPMDAKQIEEARKIYKF 221 >1VF1-A nrPDB Length = 229 Score = 286 bits (733), Expect = 3e-78, Method: Compositional matrix adjust. Identities = 142/221 (64%), Positives = 166/221 (75%) Query: 1 MAGKPKLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQVPMVEI 60 MA KP L+YFNGRG+ME IRWLLAAAGVEFEE F+ + E KL G LMFQQVPMVEI Sbjct: 1 MAAKPVLYYFNGRGKMESIRWLLAAAGVEFEEVFLETREQYEKLLQSGILMFQQVPMVEI 60 Query: 61 DGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAK 120 DGMKLVQTRAILNYIA KYNLYGKD+KERALIDMY G DL +L P E+K + Sbjct: 61 DGMKLVQTRAILNYIAGKYNLYGKDLKERALIDMYVGGTDDLMGFLLSFPFLSAEDKVKQ 120 Query: 121 IALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLISNFPL 180 A + EK SRYFPA+EKVL+ HGQD+LVGN+LS ADI L+E + VEE S +S FPL Sbjct: 121 CAFVVEKATSRYFPAYEKVLKDHGQDFLVGNRLSWADIHLLEAILMVEEKKSDALSGFPL 180 Query: 181 LKALKTRISNLPTVKKFLQPGSPRKPPADAKALEEARKIFR 221 L+A K RIS++PT+KKFL PGS RKP +D K +E R++ R Sbjct: 181 LQAFKKRISSIPTIKKFLAPGSKRKPISDDKYVETVRRVLR 221 >1B48-A nrPDB Length = 221 Score = 284 bits (726), Expect = 2e-77, Method: Compositional matrix adjust. Identities = 135/221 (61%), Positives = 170/221 (76%) Query: 2 AGKPKLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQVPMVEID 61 A KPKL+YFNGRGRME IRWLLAAAGVEFEE+F+ + E K++ DG L+F QVP+VEID Sbjct: 1 AAKPKLYYFNGRGRMESIRWLLAAAGVEFEEEFLETREQYEKMQKDGHLLFGQVPLVEID 60 Query: 62 GMKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAKI 121 GM L QTRAIL+Y+A+KYNLYGKD+KER IDMY +G DL MI + P P+EK+ Sbjct: 61 GMMLTQTRAILSYLAAKYNLYGKDLKERVRIDMYADGTQDLMMMIAVAPFKTPKEKEESY 120 Query: 122 ALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLISNFPLL 181 LI + K+RYFP FEK+L+ HG+ +LVGN+LS ADI L+E + VEEL + ++S+FPLL Sbjct: 121 DLILSRAKTRYFPVFEKILKDHGEAFLVGNQLSWADIQLLEAILMVEELSAPVLSDFPLL 180 Query: 182 KALKTRISNLPTVKKFLQPGSPRKPPADAKALEEARKIFRF 222 +A KTRISN+PT+KKFLQPGS RKPP D +E R + +F Sbjct: 181 QAFKTRISNIPTIKKFLQPGSQRKPPPDGPYVEVVRIVLKF 221 >1GUL-A nrPDB Length = 222 Score = 259 bits (662), Expect = 6e-70, Method: Compositional matrix adjust. Identities = 118/221 (53%), Positives = 167/221 (75%) Query: 1 MAGKPKLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQVPMVEI 60 MA +PKLHY NGRGRME +RW+LAAAGVEF+E+F+ + E L KL++ L+FQQVPMVEI Sbjct: 1 MAARPKLHYPNGRGRMESVRWVLAAAGVEFDEEFLETKEQLYKLQDGNHLLFQQVPMVEI 60 Query: 61 DGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAK 120 DGMKLVQTR+IL+YIA K+NL+GK++KER LIDMY EG DL E++++ P +P+++ + Sbjct: 61 DGMKLVQTRSILHYIADKHNLFGKNLKERTLIDMYVEGTLDLLELLIMHPFLKPDDQQKE 120 Query: 121 IALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLISNFPL 180 + + +K RYFP FEK+L+ HGQ +LVGN+LS AD+ L++ + +EE +++S FP Sbjct: 121 VVNMAQKAIIRYFPVFEKILRGHGQSFLVGNQLSLADVILLQTILALEEKIPNILSAFPF 180 Query: 181 LKALKTRISNLPTVKKFLQPGSPRKPPADAKALEEARKIFR 221 L+ ++SN+PT+K+FL+PGS +KPP D + IFR Sbjct: 181 LQEYTVKLSNIPTIKRFLEPGSKKKPPPDEIYVRTVYNIFR 221 >1TU7-A nrPDB Length = 208 Score = 96.3 bits (238), Expect = 1e-20, Method: Compositional matrix adjust. Identities = 66/210 (31%), Positives = 112/210 (53%), Gaps = 10/210 (4%) Query: 6 KLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQVPMVEIDGMKL 65 KL YF+ RG EPIR L ++F + I + +D +++ F Q+P + ++ Sbjct: 4 KLTYFSIRGLAEPIRLFLVDQDIKFIDDRI-AKDDFSSIKS--QFQFGQLPCLYDGDQQI 60 Query: 66 VQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLN-EMILLLPLCRPEEKDAKIALI 124 VQ+ AIL ++A KYNL G++ E IDM+ EG+ DL+ + ++ + EKD I I Sbjct: 61 VQSGAILRHLARKYNLNGENEMETTYIDMFCEGVRDLHVKYTRMIYMAYETEKDPYIKSI 120 Query: 125 KEKTKSRYFPAFEKVLQS--HGQDYLVGNKLSRADISLVELLYYVEELDSSLISNFPLLK 182 ++ FEK+L + +G++ ++G+K+S AD +L E L + LD + FPLLK Sbjct: 121 LPGELAK----FEKLLATRGNGRNLILGDKISYADYALFEELDVHQILDPHCLDKFPLLK 176 Query: 183 ALKTRISNLPTVKKFLQPGSPRKPPADAKA 212 R+ + P +K++ + K P + Sbjct: 177 VFHQRMKDRPKLKEYCEKRDAAKVPVNGNG 206 >2GSR-A nrPDB Length = 207 Score = 95.5 bits (236), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 66/194 (34%), Positives = 102/194 (52%), Gaps = 9/194 (4%) Query: 7 LHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQVPMVEIDGMKLV 66 + YF RGR E +R LLA ++E+ + + E L+ S +F+Q+P + + L Sbjct: 5 ITYFPVRGRCEAMRMLLADQDQSWKEEVV-TMETWPPLK--PSCLFRQLPKFQDGDLTLY 61 Query: 67 QTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAKIALIKE 126 Q+ AIL ++ + LYGKD KE AL+DM +G+ DL L E K Sbjct: 62 QSNAILRHLGRSFGLYGKDQKEAALVDMVNDGVEDLRCKYATLIYTNYEAGKEKYV---- 117 Query: 127 KTKSRYFPAFEKVLQSH--GQDYLVGNKLSRADISLVELLYYVEELDSSLISNFPLLKAL 184 K + FE +L + GQ ++VG+++S AD +L++LL + L+ S + FPLL A Sbjct: 118 KELPEHLKPFETLLSQNQGGQAFVVGSQISFADYNLLDLLRIHQVLNPSCLDAFPLLSAY 177 Query: 185 KTRISNLPTVKKFL 198 R+S P +K FL Sbjct: 178 VARLSARPKIKAFL 191 >2AAW-A nrPDB Length = 222 Score = 93.6 bits (231), Expect = 6e-20, Method: Compositional matrix adjust. Identities = 63/208 (30%), Positives = 104/208 (50%), Gaps = 15/208 (7%) Query: 1 MAGKPKLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAED----LGKLRNDGSLMFQQVP 56 M L+YF+ RG+ E IR + A G+E+ +K G D + + F+QVP Sbjct: 12 MGDNIVLYYFDARGKAELIRLIFAYLGIEYTDKRFGVNGDAFVEFKNFKKEKDTPFEQVP 71 Query: 57 MVEIDGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEE 116 +++I + L Q++AI+ Y++ KYN+ G+ DM G+ D++ L + E Sbjct: 72 ILQIGDLILAQSQAIVRYLSKKYNICGESELNEFYADMIFCGVQDIHYKFNNTNLFKQNE 131 Query: 117 KDAKIALIKEKTKSRYFPAFEKVLQSHGQD------YLVGNKLSRADISLVELLYYVEEL 170 + E ++ FEK+L+ + + Y VGN L+ AD+++ L +E Sbjct: 132 ----TTFLNEDL-PKWSGYFEKLLKKNHTNNNNDKYYFVGNNLTYADLAVFNLYDDIETK 186 Query: 171 DSSLISNFPLLKALKTRISNLPTVKKFL 198 S + NFPLLKA ISNLP +K ++ Sbjct: 187 YPSSLKNFPLLKAHNEFISNLPNIKNYI 214 >5D73-A nrPDB Length = 208 Score = 92.0 bits (227), Expect = 2e-19, Method: Compositional matrix adjust. Identities = 67/210 (31%), Positives = 111/210 (52%), Gaps = 10/210 (4%) Query: 6 KLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQVPMVEIDGMKL 65 KL YF RG EPIR +L G++F + I +A D +++ F Q+P + ++ Sbjct: 4 KLTYFPIRGLAEPIRLVLVDQGIKFTDDRI-NASDWPSMKS--HFHFGQLPCLYDGDHQI 60 Query: 66 VQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLN-EMILLLPLCRPEEKDAKIALI 124 VQ+ AIL ++A K+NL G + E IDM+ EG+ DL+ + ++ EKD+ I I Sbjct: 61 VQSGAILRHLARKHNLNGGNELETTHIDMFCEGVRDLHTKYTKMIYQAYDTEKDSYIKDI 120 Query: 125 KEKTKSRYFPAFEKVLQSH--GQDYLVGNKLSRADISLVELLYYVEELDSSLISNFPLLK 182 ++ FEK+L + G+++++G K+S D L E L + LD + FPLLK Sbjct: 121 LPVELAK----FEKLLATRDDGKNFILGEKISYVDFVLFEELDIHQILDPHCLDKFPLLK 176 Query: 183 ALKTRISNLPTVKKFLQPGSPRKPPADAKA 212 A R+ + P +K++ + + K P + Sbjct: 177 AYHQRMEDRPGLKEYCKQRNRAKIPVNGNG 206 >4Q5R-A nrPDB Length = 204 Score = 87.4 bits (215), Expect = 5e-18, Method: Compositional matrix adjust. Identities = 67/211 (31%), Positives = 109/211 (51%), Gaps = 10/211 (4%) Query: 1 MAGKPKLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQVPMVEI 60 MA KL Y + EPIR+LL+ +FE+ + D L+ S+ F + P++EI Sbjct: 1 MAPSYKLTYCPVKALGEPIRFLLSYGEKDFED-YRFQEGDWPNLK--PSMPFGKTPVLEI 57 Query: 61 DGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEE-KDA 119 DG + Q+ AI Y+ ++ L GKD E IDM + ++D I E K Sbjct: 58 DGKQTHQSVAISRYLGKQFGLSGKDDWENLEIDMIVDTISDFRAAIANYHYDADENSKQK 117 Query: 120 KIALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEEL-DSSLISNF 178 K +K++T Y F++V++++G YL KL+ AD V +L Y+ + L++N Sbjct: 118 KWDPLKKETIPYYTKKFDEVVKANGG-YLAAGKLTWADFYFVAILDYLNHMAKEDLVANQ 176 Query: 179 PLLKALKTRISNLPTVKKFLQPGSPRKPPAD 209 P LKAL+ ++ LP +K ++ ++PP D Sbjct: 177 PNLKALREKVLGLPAIKAWVA----KRPPTD 203 >18GS-A nrPDB Length = 210 Score = 87.0 bits (214), Expect = 6e-18, Method: Compositional matrix adjust. Identities = 62/193 (32%), Positives = 100/193 (51%), Gaps = 9/193 (4%) Query: 9 YFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQVPMVEIDGMKLVQT 68 YF RGR +R LLA G ++E+ + + E + S ++ Q+P + + L Q+ Sbjct: 8 YFPVRGRCAALRMLLADQGQSWKEEVV-TVETWQEGSLKASCLYGQLPKFQDGDLTLYQS 66 Query: 69 RAILNYIASKYNLYGKDIKERALIDMYTEGMADLN-EMILLLPLCRPEEKDAKIALIKEK 127 IL ++ LYGKD +E AL+DM +G+ DL + I L+ KD + + + Sbjct: 67 NTILRHLGRTLGLYGKDQQEAALVDMVNDGVEDLRCKYISLIYTNYEAGKDDYVKALPGQ 126 Query: 128 TKSRYFPAFEKVLQSH--GQDYLVGNKLSRADISLVELLYYVEELDSSLISNFPLLKALK 185 K FE +L + G+ ++VG+++S AD +L++LL E L + FPLL A Sbjct: 127 LKP-----FETLLSQNQGGKTFIVGDQISFADYNLLDLLLIHEVLAPGCLDAFPLLSAYV 181 Query: 186 TRISNLPTVKKFL 198 R+S P +K FL Sbjct: 182 GRLSARPKLKAFL 194 >4Q5F-A nrPDB Length = 218 Score = 85.9 bits (211), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 60/204 (29%), Positives = 100/204 (49%), Gaps = 9/204 (4%) Query: 6 KLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQVPMVEIDGMKL 65 KL YF+ RG E R + AGV+FE+ + ED L+ F Q+P++E+DG L Sbjct: 17 KLTYFDIRGLGEGARLIFHQAGVKFEDNRL-KREDWPALKPKTP--FGQLPLLEVDGEVL 73 Query: 66 VQTRAILNYIASKYNLYGKDIKERA----LIDMYTEGMADLNEMILLLPLCRPEEKDAKI 121 Q+ AI Y+ ++ L GK E A + D + + MA+L +L +K+ + Sbjct: 74 AQSAAIYRYLGRQFGLAGKTPMEEAQVDSIFDQFKDFMAELRPCFRVLAGFEEGDKEKVL 133 Query: 122 ALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLISNFPLL 181 + + ++ P EK L G +Y+VG ++ AD+ + + L E L +S L Sbjct: 134 KEVAVPARDKHLPLLEKFLAKSGSEYMVGKSVTWADLVITDSLASWESLIPDFLSGHLQL 193 Query: 182 KALKTRISNLPTVKKFL--QPGSP 203 K + LP +KK++ +P +P Sbjct: 194 KKYIEHVRELPNIKKWIAERPKTP 217 >2GLR-A nrPDB Length = 209 Score = 85.9 bits (211), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 60/192 (31%), Positives = 96/192 (50%), Gaps = 7/192 (3%) Query: 9 YFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQVPMVEIDGMKLVQT 68 YF RGR E +R LLA G ++E+ + + L + ++ Q+P E + L Q+ Sbjct: 7 YFPVRGRCEAMRMLLADQGQSWKEEVVTIDTWMQGLLKP-TCLYGQLPKFEDGDLTLYQS 65 Query: 69 RAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAKIALIKEKT 128 AIL ++ LYGK+ +E A +DM +G+ DL + L E K Sbjct: 66 NAILRHLGRSLGLYGKNQREAAQMDMVNDGVEDLRGKYVTLIYTNYENGKNDYV----KA 121 Query: 129 KSRYFPAFEKVLQSH--GQDYLVGNKLSRADISLVELLYYVEELDSSLISNFPLLKALKT 186 + FE +L + G+ ++VG+++S AD +L++LL + L + NFPLL A Sbjct: 122 LPGHLKPFETLLSQNQGGKAFIVGDQISFADYNLLDLLLIHQVLAPGCLDNFPLLSAYVA 181 Query: 187 RISNLPTVKKFL 198 R+S P +K FL Sbjct: 182 RLSARPKIKAFL 193 >1ZL9-A nrPDB Length = 207 Score = 83.2 bits (204), Expect = 9e-17, Method: Compositional matrix adjust. Identities = 61/207 (29%), Positives = 102/207 (49%), Gaps = 24/207 (11%) Query: 6 KLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQVPMVEIDGMKL 65 KL YFNGRG E R + A AG ++E+ + + E L+ + F Q+P +E+DG KL Sbjct: 5 KLTYFNGRGAGEVSRQIFAYAGQQYEDNRV-TQEQWPALKETCAAPFGQLPFLEVDGKKL 63 Query: 66 VQTRAILNYIASKYNLYGKDIKERA----LIDMYTEGMADLNEMILLLPLCRPEEKDAKI 121 Q+ AI ++A ++ L GK E A L D Y + ++ + P + Sbjct: 64 AQSHAIARFLAREFKLNGKTAWEEAQVNSLADQYKDYSSEARPYFYAVMGFGPGD----- 118 Query: 122 ALIKEKTKSRYFPAFEK-------VLQSHGQDYLVGNKLSRADISLVELLYYVEEL--DS 172 ++ K + PAFEK L++ G +LVG+ L+ D+++ + + +L Sbjct: 119 --VETLKKDIFLPAFEKFYGFLVNFLKASGSGFLVGDSLTWIDLAIAQ---HSADLIAKG 173 Query: 173 SLISNFPLLKALKTRISNLPTVKKFLQ 199 S FP LKA +I +P +KK+++ Sbjct: 174 GDFSKFPELKAHAEKIQAIPQIKKWIE 200 >1GSQ-A nrPDB Length = 202 Score = 82.0 bits (201), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 57/198 (28%), Positives = 100/198 (50%), Gaps = 6/198 (3%) Query: 4 KPKLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQVPMVEIDGM 63 K LHYF GR E R++LAA G EF ++ + A D L+ ++ +P+++IDG Sbjct: 2 KYTLHYFPLMGRAELCRFVLAAHGEEFTDRVVEMA-DWPNLK--ATMYSNAMPVLDIDGT 58 Query: 64 KLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAKIAL 123 K+ Q+ I ++A ++ L GK E+ +D TE + D+ ++ + PE + Sbjct: 59 KMSQSMCIARHLAREFGLDGKTSLEKYRVDEITETLQDIFNDVVKIKF-APEAAKEAVQQ 117 Query: 124 IKEKTKSRYFPAFEKVLQSH--GQDYLVGNKLSRADISLVELLYYVEELDSSLISNFPLL 181 EK+ R P E +L S+ G + VGN ++ AD+ L + L+ + P + Sbjct: 118 NYEKSCKRLAPFLEGLLVSNGGGDGFFVGNSMTLADLHCYVALEVPLKHTPELLKDCPKI 177 Query: 182 KALKTRISNLPTVKKFLQ 199 AL+ R++ P + +L+ Sbjct: 178 VALRKRVAECPKIAAYLK 195 >1YQ1-A nrPDB Length = 208 Score = 79.3 bits (194), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 62/201 (30%), Positives = 100/201 (49%), Gaps = 13/201 (6%) Query: 6 KLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQVPMVEIDGMKL 65 KL YF RG EPIR L AGV+FEE + D L S +Q+P++ IDG +L Sbjct: 5 KLTYFFFRGLGEPIRLLFHLAGVQFEE--VRMNPDQTWLDIKDSTPMKQLPVLNIDGFEL 62 Query: 66 VQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAKIALIK 125 Q+ AIL Y+A K+ GK +E A +D + D + E + K A Sbjct: 63 PQSGAILRYLARKFGFAGKTPEEEAWVDAVHDLFKDF---LAEFKKFAAERRSGKSAEEV 119 Query: 126 EKTKSRYF-PA-------FEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLISN 177 EK +S +F PA +L+ +L+G+ ++ AD+ +V+ L ++ S Sbjct: 120 EKFRSEFFLPARNTYFNILNGLLEKSNSGFLIGSDITFADLVVVDNLLTLKNYGLFDESE 179 Query: 178 FPLLKALKTRISNLPTVKKFL 198 F L AL+ ++++ P +K+++ Sbjct: 180 FTKLAALREKVNSYPGIKEYI 200 >5AN1-A nrPDB Length = 219 Score = 79.0 bits (193), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 64/217 (29%), Positives = 102/217 (47%), Gaps = 17/217 (7%) Query: 5 PKLHYFNGRGRMEPIRWLLAAAGVEFEEKF--IGSAEDLGK-----LRNDGSLMFQQVPM 57 P L Y+ R +PIR +L G EFEEK +G A D K ++ L F +P Sbjct: 3 PVLGYWKTRALCQPIRLMLGYTGTEFEEKNYPVGDAPDYDKSEWLAVKFKLGLAFPNLPY 62 Query: 58 VEIDG-MKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEE 116 IDG +K+ Q++AI+ Y+A K+ L G +E DM + D++E + E+ Sbjct: 63 Y-IDGDVKITQSKAIMRYLARKHGLCGTTPEELVRTDMIECQLTDMHEAFFTVTYEHYEQ 121 Query: 117 KDAKIALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLIS 176 KDA A + K + + L S + + G+KL+ D E+ LD + + Sbjct: 122 KDAYTASLPAKLRQ-----YSDFLGS--RPWFAGDKLTYIDFLAYEIFDQHLSLDRTCLD 174 Query: 177 NFPLLKALKTRISNLPTVKKFL-QPGSPRKPPADAKA 212 F L+A + R +L +KK++ P +KP + A Sbjct: 175 GFKNLQAFQKRFEDLEAIKKYMASPKFLKKPICNKYA 211 >3KXO-A nrPDB Length = 202 Score = 72.4 bits (176), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 57/210 (27%), Positives = 104/210 (49%), Gaps = 28/210 (13%) Query: 6 KLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQVPMVEIDGMKL 65 KL YFN RGR E IR++ A +++E+ I A D ++++ +L F ++P++E+DG+ L Sbjct: 8 KLTYFNMRGRAEIIRYIFAYLDIQYEDHRIEQA-DWPEIKS--TLPFGKIPILEVDGLTL 64 Query: 66 VQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRP---EEKDAKIA 122 Q+ AI Y+ +L G E+ +D + + D C P +++D K Sbjct: 65 HQSLAIARYLTKNTDLAGNTEMEQCHVDAIVDTLDDFMS-------CFPWAEKKQDVKEQ 117 Query: 123 LIKEKTKSRYFPAFEKVLQSH--GQDYLVGNKLSRAD----ISLVELLYYVEELDSSLIS 176 + E P + L ++ G+++L+GN ++ AD I LL + L+ Sbjct: 118 MFNELLTYNA-PHLMQDLDTYLGGREWLIGNSVTWADFYWEICSTTLLVF----KPDLLD 172 Query: 177 NFPLLKALKTRISNLPTVKKFLQPGSPRKP 206 N P L L+ ++ +P V +++ R+P Sbjct: 173 NHPRLVTLRKKVQAIPAVANWIK----RRP 198 >4Q5Q-A nrPDB Length = 219 Score = 70.9 bits (172), Expect = 5e-13, Method: Compositional matrix adjust. Identities = 62/210 (29%), Positives = 98/210 (46%), Gaps = 14/210 (6%) Query: 3 GKPKLHYFNGRGRMEPIRWLLAAAGVEFEEKF--IGSAEDLGKL-----RNDGSLMFQQV 55 +P L Y++ RG +PIR LL +GV+F +K IG A D + + + L F + Sbjct: 2 SQPILGYWDIRGYAQPIRLLLTYSGVDFVDKRYQIGPAPDFDRSEWLNEKFNLGLDFPNL 61 Query: 56 PMVEIDG-MKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRP 114 P IDG MK+ QT AIL Y+ KY L G + E I M + D+ M ++ +C Sbjct: 62 PYY-IDGDMKMTQTFAILRYLGRKYKLNGSNDHEEIRISMAEQQTEDM--MAAMIRVCYD 118 Query: 115 EEKDAKIALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSL 174 D K+ K+ K + H ++ G +S D +L E L +V+ + + Sbjct: 119 ANCD-KLKPDYLKSLPDCLKLMSKFVGEHA--FIAGANISYVDFNLYEYLCHVKVMVPEV 175 Query: 175 ISNFPLLKALKTRISNLPTVKKFLQPGSPR 204 F LK R+ +LP V +++ P+ Sbjct: 176 FGQFENLKRYVERMESLPRVSDYIKKQQPK 205 >2FHE-A nrPDB Length = 216 Score = 69.7 bits (169), Expect = 8e-13, Method: Compositional matrix adjust. Identities = 58/206 (28%), Positives = 95/206 (46%), Gaps = 27/206 (13%) Query: 6 KLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQ----------V 55 KL Y+ RG +P+R LL G ++EE+ R+DG F + + Sbjct: 3 KLGYWKIRGLQQPVRLLLEYLGEKYEEQIYE--------RDDGEKWFSKKFELGLDLPNL 54 Query: 56 PMVEIDGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPE 115 P D KL Q+ AIL YIA K+ + G +ERA + M DL + I + +P+ Sbjct: 55 PYYIDDKCKLTQSLAILRYIADKHGMIGTTSEERARVSMIEGAAVDLRQGISRISY-QPK 113 Query: 116 EKDAKIALIKEKTKSRYFPAFEKVLQSH-GQD-YLVGNKLSRADISLVELLYYVEELDSS 173 + K +K+ P K+ G++ YL G +S D + E L + L+ Sbjct: 114 FEQLKEGYLKD------LPTTMKMWSDFLGKNPYLRGTSVSHVDFMVYEALDAIRYLEPH 167 Query: 174 LISNFPLLKALKTRISNLPTVKKFLQ 199 + +FP L+ +RI LP++K +++ Sbjct: 168 CLDHFPNLQQFMSRIEALPSIKAYME 193 >5Y9Z-A nrPDB Length = 199 Score = 68.6 bits (166), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 54/199 (27%), Positives = 102/199 (51%), Gaps = 18/199 (9%) Query: 6 KLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQVPMVEIDGMKL 65 KL YFN RGR E IR++ A +++E+ I A D K++ +L F ++P++E++G+ L Sbjct: 5 KLLYFNMRGRAEIIRYIFAYLDIKYEDHRIEQA-DWPKIK--PTLPFGKIPVLEVEGLTL 61 Query: 66 VQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAKIALIK 125 Q+ AI Y+ +L GK E+ +D + L++ + L P E +D +K Sbjct: 62 HQSLAIARYLTKNTDLAGKTELEQCQVDAVVDT---LDDFMSLFPWAE-ENQD-----LK 112 Query: 126 EKT----KSRYFPAFEKVLQSH--GQDYLVGNKLSRADISLVELLYYVEELDSSLISNFP 179 E+T +R P K L ++ +++ +GN ++ AD + L L+ +P Sbjct: 113 ERTFNDLLTRQAPHLLKDLDTYLGDKEWFIGNYVTWADFYWDICSTTLLVLKPDLLGIYP 172 Query: 180 LLKALKTRISNLPTVKKFL 198 L +L+ ++ +P + ++ Sbjct: 173 RLVSLRNKVQAIPAISAWI 191 >2WRT-A nrPDB Length = 218 Score = 68.2 bits (165), Expect = 3e-12, Method: Compositional matrix adjust. Identities = 60/205 (29%), Positives = 93/205 (45%), Gaps = 25/205 (12%) Query: 6 KLHYFNGRGRMEPIRWLLAAA---------GVEFEEKFIGSAEDLGKLRNDGSLMFQQVP 56 KL Y+ RG +P+R LL G + EK++G ++G L +P Sbjct: 4 KLGYWKIRGLQQPVRLLLEYLGEEYEEHLYGRDDREKWLGDKFNMG-------LDLPNLP 56 Query: 57 MVEIDGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEE 116 D KL Q+ AI+ YIA K+ + G +ERA I M DL M + P+ Sbjct: 57 YYIDDKCKLTQSVAIMRYIADKHGMLGSTPEERARISMIEGAAMDLR-MGFVRVCYNPKF 115 Query: 117 KDAKIALIKEKTKSRYFPAFEKVLQSHGQD--YLVGNKLSRADISLVELLYYVEELDSSL 174 ++ K +KE P K+ + D YL G+ +S D + E L + L Sbjct: 116 EEVKGDYLKE------LPTTLKMWSNFLGDRHYLTGSSVSHVDFMVYEALDCIRYLAPQC 169 Query: 175 ISNFPLLKALKTRISNLPTVKKFLQ 199 + +FP LK K+RI +LP +K +++ Sbjct: 170 LEDFPKLKEFKSRIEDLPKIKAYME 194 >2HNL-A nrPDB Length = 225 Score = 66.2 bits (160), Expect = 1e-11, Method: Compositional matrix adjust. Identities = 56/199 (28%), Positives = 99/199 (49%), Gaps = 10/199 (5%) Query: 4 KPKLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQVPMVEIDGM 63 K L YFNGRGR E IR L A A V +E+ I + ++ L+ F VPM+ + G Sbjct: 27 KYTLTYFNGRGRAEVIRLLFALANVSYEDNRI-TRDEWKYLK--PRTPFGHVPMLNVSGN 83 Query: 64 KLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAKIAL 123 L ++ AI + ++ L G + E A I + +L + L+P + K L Sbjct: 84 VLGESHAIELLLGGRFGLLGTNDWEEAKIMAVVLNIDELFQK--LIPWTHEKNTTKKAEL 141 Query: 124 IKEKTKSRYFP---AFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLISNFPL 180 + ++S P +EK L+ ++VGNK+S AD+++ +L ++ D + +P Sbjct: 142 FRNLSESDVMPFLGRYEKFLKESTTGHIVGNKVSVADLTVFNMLMTLD--DEVKLEEYPQ 199 Query: 181 LKALKTRISNLPTVKKFLQ 199 L + +I +P +K++++ Sbjct: 200 LASFVNKIGQMPGIKEWIK 218 >2WDU-A nrPDB Length = 211 Score = 65.9 bits (159), Expect = 1e-11, Method: Compositional matrix adjust. Identities = 57/196 (29%), Positives = 94/196 (47%), Gaps = 13/196 (6%) Query: 6 KLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQVPMVEIDG--- 62 KL YF RGR EPIR LL AGV+FE+ + + + ++ +L +VP++++ G Sbjct: 7 KLWYFQFRGRAEPIRLLLTCAGVKFED-YQFTMDQWPTIKP--TLPGGRVPLLDVTGPDG 63 Query: 63 --MKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAK 120 + ++ AI +A ++ + G+ +E LI+ DL + + EK+AK Sbjct: 64 KLRRYQESMAIARLLARQFKMMGETDEEYYLIERIIGECEDLYREVYTIFRTPQGEKEAK 123 Query: 121 IALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYV-EELDSSLISNFP 179 I KE + L+S G ++ GN+++ D+ L L +V E + L FP Sbjct: 124 IKEFKENNGPTLLKLVSESLESSGGKHVAGNRITLGDLFLFTTLTHVMETVPGFLEQKFP 183 Query: 180 LL----KALKTRISNL 191 L K+L T S L Sbjct: 184 KLHEFHKSLPTSCSRL 199 >1U3I-A nrPDB Length = 211 Score = 63.2 bits (152), Expect = 9e-11, Method: Compositional matrix adjust. Identities = 60/215 (27%), Positives = 118/215 (54%), Gaps = 17/215 (7%) Query: 1 MAGKP-KLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQVPMVE 59 MAG+ K+ YF+GRGR E IR L AAGV++E++ I S +D K++ ++ ++P V+ Sbjct: 1 MAGEHIKVIYFDGRGRAESIRMTLVAAGVDYEDERI-SFQDWPKIKP--TIPGGRLPAVK 57 Query: 60 IDGMK-----LVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRP 114 + ++++ AI Y+A K+++ G+ +E ++ G A+ E L +P Sbjct: 58 VTDDHGHVKWMLESLAIARYMAKKHHMMGETDEEYYSVEKLI-GQAEDVEHEYHKTLMKP 116 Query: 115 EEKDAKIA--LIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDS 172 +E+ KI ++ K + E + S G+ VG+K++ AD+ L+ ++ +V +LD Sbjct: 117 QEEKEKITKEILNGKVPVLFNMICESLKGSTGK-LAVGDKVTLADLVLIAVIDHVTDLDK 175 Query: 173 SLISN-FP-LLKALKTRISNLPTVKKFL--QPGSP 203 ++ +P + K + +++ P + K+L +P +P Sbjct: 176 GFLTGKYPEIHKHRENLLASSPRLAKYLSNRPATP 210 >2CZ2-A nrPDB Length = 223 Score = 63.2 bits (152), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 59/216 (27%), Positives = 102/216 (47%), Gaps = 20/216 (9%) Query: 2 AGKPKLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMF---QQVPMV 58 AGKP L+ + +R LA G+++E I +D G+ + +QVP + Sbjct: 10 AGKPILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPAL 69 Query: 59 EIDGMKLVQTRAILNYIASKY---NLYGKDIKERALI----DMYTEGMADLNEMILLLPL 111 +IDG+ +VQ+ AI+ Y+ L +D ++RA++ D+ G+ L + +L + Sbjct: 70 KIDGITIVQSLAIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQV 129 Query: 112 CRPEEKDAKIALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELD 171 +E + A +K + F A EK+LQS Y VG+++S AD+ LV + E Sbjct: 130 G--QENQMQWA---QKVITSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVANAERFK 184 Query: 172 SSLISNFPLLKALKTRISNLPTVKKFLQPGSPRKPP 207 L S +P + + + L + Q PR+ P Sbjct: 185 VDL-SPYPTISHINKELLAL----EVFQVSHPRRQP 215 >2CA8-A nrPDB Length = 211 Score = 62.0 bits (149), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 60/205 (29%), Positives = 108/205 (52%), Gaps = 18/205 (8%) Query: 6 KLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQVPMVEIDGMK- 64 K+ YFNGRGR E IR L AAGV +E++ I S +D K++ ++ ++P V+I Sbjct: 7 KVIYFNGRGRAESIRMTLVAAGVNYEDERI-SFQDWPKIKP--TIPGGRLPAVKITDNHG 63 Query: 65 ----LVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAK 120 +V++ AI Y+A K+++ G +E ++ G A+ E L +PEE+ K Sbjct: 64 HVKWMVESLAIARYMAKKHHMMGGTEEEYYNVEKLI-GQAEDLEHEYYKTLMKPEEEKQK 122 Query: 121 IALIKEKTKSRYFPAFEKV----LQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLIS 176 I IKE + P + L++ VG+K++ AD+ L+ ++ +V +LD ++ Sbjct: 123 I--IKEILNGK-VPVLLDIICESLKASTGKLAVGDKVTLADLVLIAVIDHVTDLDKEFLT 179 Query: 177 N-FP-LLKALKTRISNLPTVKKFLQ 199 +P + K + +++ P + K+L Sbjct: 180 GKYPEIHKHRENLLASSPRLAKYLS 204 >3GTU-B nrPDB Length = 224 Score = 59.7 bits (143), Expect = 9e-10, Method: Compositional matrix adjust. Identities = 60/225 (26%), Positives = 92/225 (40%), Gaps = 24/225 (10%) Query: 7 LHYFNGRGRMEPIRWLLAAAGVEFEEK--FIGSAEDLGK-----LRNDGSLMFQQVPMVE 59 L Y++ RG IR LL +EEK G A D + ++ L F +P + Sbjct: 8 LGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLPYL- 66 Query: 60 IDGM-KLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKD 118 +DG K+ Q+ AIL YIA K+N+ G+ +E+ +D+ + D L+ LC + Sbjct: 67 LDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQ--LIRLCYSSD-- 122 Query: 119 AKIALIKEKTKSRYFPAFEKVLQSHGQ-----DYLVGNKLSRADISLVELLYYVEELDSS 173 EK K +Y L+ + G KL+ D ++L D Sbjct: 123 ------HEKLKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFDPK 176 Query: 174 LISNFPLLKALKTRISNLPTVKKFLQPGSPRKPPADAKALEEARK 218 + FP LKA R L + +LQ K P + K + K Sbjct: 177 CLDEFPNLKAFMCRFEALEKIAAYLQSDQFCKMPINNKMAQWGNK 221 >1HNA-A nrPDB Length = 217 Score = 57.8 bits (138), Expect = 4e-09, Method: Compositional matrix adjust. Identities = 59/206 (28%), Positives = 94/206 (45%), Gaps = 24/206 (11%) Query: 7 LHYFNGRGRMEPIRWLLAAAGVEFEEK--FIGSAEDLGKLR--NDG---SLMFQQVPMVE 59 L Y+N RG IR LL +EEK +G A D + + N+ L F +P + Sbjct: 4 LGYWNIRGLAHSIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYL- 62 Query: 60 IDGM-KLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKD 118 IDG K+ Q+ AIL YIA K+NL G+ KE+ D+ D + L LC + Sbjct: 63 IDGTHKITQSNAILRYIARKHNLCGESEKEQIREDILENQFMD--SRMQLAKLCYDPD-- 118 Query: 119 AKIALIKEKTKSRYFPAFEKVLQSHG-----QDYLVGNKLSRADISLVELLYYVEELDSS 173 EK K Y A ++L+ + Q + +G+K++ D ++L + + S Sbjct: 119 ------FEKLKPEYLQALPEMLKLYSQFLGKQPWFLGDKITFVDFIAYDVLERNQVFEPS 172 Query: 174 LISNFPLLKALKTRISNLPTVKKFLQ 199 + FP LK +R L + +++ Sbjct: 173 CLDAFPNLKDFISRFEGLEKISAYMK 198 >1FHE-A nrPDB Length = 217 Score = 57.4 bits (137), Expect = 5e-09, Method: Compositional matrix adjust. Identities = 56/203 (27%), Positives = 85/203 (41%), Gaps = 21/203 (10%) Query: 6 KLHYFNGRGRMEPIRWLLAAA---------GVEFEEKFIGSAEDLGKLRNDGSLMFQQVP 56 KL Y+ RG +P+R L G + EK++ ++G L +P Sbjct: 3 KLGYWKLRGLAQPVRLFLEYLGEEYEEHLYGRDDREKWMSEKFNMG-------LDLPNLP 55 Query: 57 MVEIDGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEE 116 D KL Q+ AI+ YIA K+ + G +ERA I M DL I +C Sbjct: 56 YYIDDKCKLTQSVAIMRYIADKHGMLGTTPEERARISMIEGAAMDLR--IGFGRVCY-NP 112 Query: 117 KDAKIALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLIS 176 K ++ K + + L + YL G+ +S D L E L + L + Sbjct: 113 KFEEVKEEYVKELPKTLKMWSDFLGD--RHYLTGSSVSHVDFMLYETLDSIRYLAPHCLD 170 Query: 177 NFPLLKALKTRISNLPTVKKFLQ 199 FP LK K+RI LP +K +++ Sbjct: 171 EFPKLKEFKSRIEALPKIKAYME 193 >1B4P-A nrPDB Length = 217 Score = 56.6 bits (135), Expect = 8e-09, Method: Compositional matrix adjust. Identities = 58/218 (26%), Positives = 96/218 (44%), Gaps = 24/218 (11%) Query: 7 LHYFNGRGRMEPIRWLLAAAGVEFEEK--FIGSAEDLGKLR--NDG---SLMFQQVPMVE 59 L Y+N RG PIR LL +EEK +G A D + + N+ L F +P + Sbjct: 4 LGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLPYL- 62 Query: 60 IDGM-KLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKD 118 IDG K+ Q+ AI+ Y+A K++L G+ +ER +D+ E A + L + P+ Sbjct: 63 IDGSRKITQSNAIMRYLARKHHLCGETEEERIRVDV-LENQAMDTRLQLAMVCYSPD--- 118 Query: 119 AKIALIKEKTKSRYFPAFEKVLQSHG-----QDYLVGNKLSRADISLVELLYYVEELDSS 173 E+ K Y + ++ + Q + GNK++ D + ++L + Sbjct: 119 ------FERKKPEYLEGLPEKMKLYSEFLGKQPWFAGNKITYVDFLVYDVLDQHRIFEPK 172 Query: 174 LISNFPLLKALKTRISNLPTVKKFLQPGSPRKPPADAK 211 + FP LK R L + +++ G P AK Sbjct: 173 CLDAFPNLKDFVARFEGLKKISDYMKSGRFLSKPIFAK 210 >5F07-A nrPDB Length = 213 Score = 56.6 bits (135), Expect = 9e-09, Method: Compositional matrix adjust. Identities = 50/163 (30%), Positives = 81/163 (49%), Gaps = 18/163 (11%) Query: 52 FQQVPMVEIDGMKLVQTRAILNYIASKY-----NLYGKDIKERALIDMYTEGMA-DLNEM 105 F QVP+VE KL ++RAI+ Y A+KY NL G ++E+AL+D + E A + N++ Sbjct: 50 FGQVPVVEDGDFKLFESRAIIRYYAAKYEDRGPNLLGNTLEEKALVDQWLEIEAHNFNDL 109 Query: 106 -------ILLLPLCRPEEKDAKIALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADI 158 +++LP ++ D+++ E+ + +EK L YL G+ + AD+ Sbjct: 110 VFNIVFQVVILPRI-GQQGDSELVRTYEEKLEKVLDVYEKRLSK--SKYLAGDSFTLADL 166 Query: 159 S-LVELLYYVEELD-SSLISNFPLLKALKTRISNLPTVKKFLQ 199 S L Y V E L+ + L A IS+ P KK + Sbjct: 167 SHLPATRYLVNEAGLGHLVKDRKKLNAWWEDISSRPAWKKLMN 209 >1XWK-A nrPDB Length = 218 Score = 55.1 bits (131), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 57/206 (27%), Positives = 93/206 (45%), Gaps = 24/206 (11%) Query: 7 LHYFNGRGRMEPIRWLLAAAGVEFEEK--FIGSAEDLGKLR--NDG---SLMFQQVPMVE 59 L Y++ RG IR LL +EEK +G A D + + N+ L F +P + Sbjct: 5 LGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYL- 63 Query: 60 IDG-MKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKD 118 IDG K+ Q+ AIL YIA K+NL G+ +E+ +D+ D N M L + PE Sbjct: 64 IDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMD-NHMQLGMICYNPE--- 119 Query: 119 AKIALIKEKTKSRYFPAFEKVLQSHGQ-----DYLVGNKLSRADISLVELLYYVEELDSS 173 EK K +Y + L+ + + + GNK++ D + ++L + Sbjct: 120 ------FEKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPK 173 Query: 174 LISNFPLLKALKTRISNLPTVKKFLQ 199 + FP LK +R L + +++ Sbjct: 174 CLDAFPNLKDFISRFEGLEKISAYMK 199 >1DUG-A nrPDB Length = 234 Score = 55.1 bits (131), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 61/207 (29%), Positives = 96/207 (46%), Gaps = 27/207 (13%) Query: 5 PKLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRN---DGSLMFQQVPMVEID 61 P L Y+ +G ++P R LL E E+ + ++ K RN + L F +P ID Sbjct: 2 PILGYWKIKGLVQPTR-LLLEYLEEKYEEHLYERDEGDKWRNKKFELGLEFPNLPYY-ID 59 Query: 62 G-MKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAK 120 G +KL Q+ AI+ YIA K+N+ G KERA I M + D+ + ++ Sbjct: 60 GDVKLTQSMAIIRYIADKHNMLGGCPKERAEISMLEGAVLDIRYGV------------SR 107 Query: 121 IALIK--EKTKSRYFPAFEKVLQ------SHGQDYLVGNKLSRADISLVELLYYVEELDS 172 IA K E K + ++L+ H + YL G+ ++ D L + L V +D Sbjct: 108 IAYSKDFETLKVDFLSKLPEMLKMFEDRLCH-KTYLNGDHVTHPDFMLYDALDVVLYMDP 166 Query: 173 SLISNFPLLKALKTRISNLPTVKKFLQ 199 + FP L K RI +P + K+L+ Sbjct: 167 MCLDAFPKLVCFKKRIEAIPQIDKYLK 193 >5FWG-A nrPDB Length = 217 Score = 54.7 bits (130), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 59/223 (26%), Positives = 100/223 (44%), Gaps = 20/223 (8%) Query: 7 LHYFNGRGRMEPIRWLLAAAGVEFEEK--FIGSAEDLGKLR--NDG---SLMFQQVPMVE 59 L Y+N RG PIR LL +EEK +G A D + + N+ L F +P + Sbjct: 4 LGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLPYL- 62 Query: 60 IDGM-KLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPE--- 115 IDG K+ Q+ AI+ Y+A K++L G+ +ER D+ + D N M L++ P+ Sbjct: 63 IDGSRKITQSNAIMRYLARKHHLCGETEEERIRADIVENQVMD-NRMQLIMLCYNPDFEK 121 Query: 116 EKDAKIALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLI 175 +K + I EK K + + L + + G+K++ D ++L + + Sbjct: 122 QKPEFLKTIPEKMK-----LYSEFLGK--RPWFAGDKVTYVDFLAYDILDQYHIFEPKCL 174 Query: 176 SNFPLLKALKTRISNLPTVKKFLQPGSPRKPPADAKALEEARK 218 FP LK R L + +++ P +K + + K Sbjct: 175 DAFPNLKDFLARFEGLKKISAYMKSSRYLSTPIFSKLAQWSNK 217 >1B8X-A nrPDB Length = 280 Score = 54.7 bits (130), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 61/207 (29%), Positives = 96/207 (46%), Gaps = 27/207 (13%) Query: 5 PKLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRN---DGSLMFQQVPMVEID 61 P L Y+ +G ++P R LL E E+ + ++ K RN + L F +P ID Sbjct: 2 PILGYWKIKGLVQPTR-LLLEYLEEKYEEHLYERDEGDKWRNKKFELGLEFPNLPYY-ID 59 Query: 62 G-MKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAK 120 G +KL Q+ AI+ YIA K+N+ G KERA I M + D+ + ++ Sbjct: 60 GDVKLTQSMAIIRYIADKHNMLGGCPKERAEISMLEGAVLDIRYGV------------SR 107 Query: 121 IALIK--EKTKSRYFPAFEKVLQ------SHGQDYLVGNKLSRADISLVELLYYVEELDS 172 IA K E K + ++L+ H + YL G+ ++ D L + L V +D Sbjct: 108 IAYSKDFETLKVDFLSKLPEMLKMFEDRLCH-KTYLNGDHVTHPDFMLYDALDVVLYMDP 166 Query: 173 SLISNFPLLKALKTRISNLPTVKKFLQ 199 + FP L K RI +P + K+L+ Sbjct: 167 MCLDAFPKLVCFKKRIEAIPQIDKYLK 193 >1BG5-A nrPDB Length = 254 Score = 54.7 bits (130), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 58/201 (28%), Positives = 94/201 (46%), Gaps = 15/201 (7%) Query: 5 PKLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRN---DGSLMFQQVPMVEID 61 P L Y+ +G ++P R LL E E+ + ++ K RN + L F +P ID Sbjct: 3 PILGYWKIKGLVQPTR-LLLEYLEEKYEEHLYERDEGDKWRNKKFELGLEFPNLPYY-ID 60 Query: 62 G-MKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAK 120 G +KL Q+ AI+ YIA K+N+ G KERA I M + D+ + + + E K Sbjct: 61 GDVKLTQSMAIIRYIADKHNMLGGCPKERAEISMLEGAVLDIRYGVSRIAYSKDFET-LK 119 Query: 121 IALIKEKTKSRYFPAFEKVLQSH--GQDYLVGNKLSRADISLVELLYYVEELDSSLISNF 178 + + + P K+ + + YL G+ ++ D L + L V +D + F Sbjct: 120 VDFLSK------LPEMLKMFEDRLCHKTYLNGDHVTHPDFMLYDALDVVLYMDPMCLDAF 173 Query: 179 PLLKALKTRISNLPTVKKFLQ 199 P L K RI +P + K+L+ Sbjct: 174 PKLVCFKKRIEAIPQIDKYLK 194 >4PNG-A nrPDB Length = 229 Score = 54.7 bits (130), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 42/149 (28%), Positives = 72/149 (48%), Gaps = 14/149 (9%) Query: 53 QQVPMVEIDGMKLVQTRAILNYIASKY----NLYGKDIKERALIDM---YTEGMADLNEM 105 VP +E DG + + AI+ Y+ SKY +LY KD+ +RA++D + G+ N Sbjct: 59 HTVPTLEDDGHYIWDSHAIIAYLVSKYGKTDSLYPKDLLQRAVVDQRLHFESGVIFANA- 117 Query: 106 ILLLPLCRPEEKDAKIALIKEKTKS--RYFPAFEKVLQSHGQDYLVGNKLSRADISLVEL 163 L + +P + + KE+ + + EK L G DY+ GN+L+ AD S++ Sbjct: 118 --LRSITKPLFAGKQTMIPKERYDAIIEVYDFLEKFLA--GNDYVAGNQLTIADFSIIST 173 Query: 164 LYYVEELDSSLISNFPLLKALKTRISNLP 192 + +E + +P + A R+ LP Sbjct: 174 VSSLEVFVKVDTTKYPRIAAWFKRLQKLP 202 >1FW1-A nrPDB Length = 216 Score = 54.7 bits (130), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 50/194 (25%), Positives = 96/194 (49%), Gaps = 10/194 (5%) Query: 2 AGKPKLH-YFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGK-LRNDGSLM--FQQVPM 57 AGKP L+ YF +R LA G++++ I +D G+ D + +QVP Sbjct: 3 AGKPILYSYFRSSCSWR-VRIALALKGIDYKTVPINLIKDGGQQFSKDFQALNPMKQVPT 61 Query: 58 VEIDGMKLVQTRAILNYIASKY---NLYGKDIKERALIDMYTEGMADLNEMILLLPLCRP 114 ++IDG+ + Q+ AI+ Y+ L +D K+RA + M ++ +A + + L + + Sbjct: 62 LKIDGITIHQSLAIIEYLEETRPTPRLLPQDPKKRASVRMISDLIAGGIQPLQNLSVLKQ 121 Query: 115 EEKDAKIALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSL 174 ++ ++ + F A E++LQS Y VG++++ AD+ LV + E L Sbjct: 122 VGEEMQLTWAQNAITCG-FNALEQILQSTAGIYCVGDEVTMADLCLVPQVANAERFKVDL 180 Query: 175 ISNFPLLKALKTRI 188 + +P + ++ R+ Sbjct: 181 -TPYPTISSINKRL 193 >4GTU-A nrPDB Length = 217 Score = 53.1 bits (126), Expect = 8e-08, Method: Compositional matrix adjust. Identities = 55/206 (26%), Positives = 92/206 (44%), Gaps = 24/206 (11%) Query: 7 LHYFNGRGRMEPIRWLLAAAGVEFEEK--FIGSAEDLGKLR--NDG---SLMFQQVPMVE 59 L Y++ RG IR LL +EEK +G A D + + N+ L F +P + Sbjct: 4 LGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYL- 62 Query: 60 IDG-MKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKD 118 IDG K+ Q+ AIL YIA K+NL G+ +E+ +D+ D++ L +C + Sbjct: 63 IDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQAMDVSNQ--LARVCYSPD-- 118 Query: 119 AKIALIKEKTKSRYFPAFEKVLQSHGQ-----DYLVGNKLSRADISLVELLYYVEELDSS 173 EK K Y ++Q Q + VG+K++ D ++L + + Sbjct: 119 ------FEKLKPEYLEELPTMMQHFSQFLGKRPWFVGDKITFVDFLAYDVLDLHRIFEPN 172 Query: 174 LISNFPLLKALKTRISNLPTVKKFLQ 199 + FP LK +R L + +++ Sbjct: 173 CLDAFPNLKDFISRFEGLEKISAYMK 198 >4YH2-A nrPDB Length = 222 Score = 52.8 bits (125), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 44/155 (28%), Positives = 76/155 (49%), Gaps = 26/155 (16%) Query: 53 QQVPMVEIDGMKLVQTRAILNYIASKYN----LYGKDIKERALID---------MYTEGM 99 VP +E DG + + AI+ Y+ SKY LY KD +RA++D ++ G+ Sbjct: 53 HTVPTLEDDGHYIWDSHAIIAYLVSKYADSDALYPKDPLKRAVVDQRLHFESGVVFANGI 112 Query: 100 ADLNEMILLLPLCR-PEEK-DAKIALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRAD 157 +++ +L + P+E+ DA I + + E L+ GQDY+ GN+L+ AD Sbjct: 113 RSISKSVLFQGQTKVPKERYDAIIEI---------YDFVETFLK--GQDYIAGNQLTIAD 161 Query: 158 ISLVELLYYVEELDSSLISNFPLLKALKTRISNLP 192 SLV + +E + + +P + A ++ LP Sbjct: 162 FSLVSSVASLEAFVALDTTKYPRIGAWIKKLEQLP 196 >1M0U-A nrPDB Length = 249 Score = 52.0 bits (123), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 43/196 (21%), Positives = 96/196 (48%), Gaps = 8/196 (4%) Query: 7 LHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQVPMVEIDGMKLV 66 L YFN + EP+R+L A E+E+ + + ++ L+ ++ Q+P++E+DG ++ Sbjct: 52 LFYFNVKALAEPLRYLFAYGNQEYEDVRV-TRDEWPALK--PTMPMGQMPVLEVDGKRVH 108 Query: 67 QTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEE--KDAKIALI 124 Q+ ++ ++A L G E ID+ + + D I ++ PE+ K+ K+ + Sbjct: 109 QSISMARFLAKTVGLCGATPWEDLQIDIVVDTINDFRLKIAVVSY-EPEDEIKEKKLVTL 167 Query: 125 KEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEEL-DSSLISNFPLLKA 183 + Y E+ ++ + +G KL+ AD+ + Y+ + L+ +P L+ Sbjct: 168 NAEVIPFYLEKLEQTVKDNDGHLALG-KLTWADVYFAGITDYMNYMVKRDLLEPYPALRG 226 Query: 184 LKTRISNLPTVKKFLQ 199 + ++ L +K +++ Sbjct: 227 VVDAVNALEPIKAWIE 242 >5F06-A nrPDB Length = 216 Score = 50.1 bits (118), Expect = 8e-07, Method: Compositional matrix adjust. Identities = 46/160 (28%), Positives = 75/160 (46%), Gaps = 18/160 (11%) Query: 52 FQQVPMVEIDGMKLVQTRAILNYIASKYNLYGKD------IKERALIDMYTE-------- 97 F Q+P +E D + L ++RAI +YIA K+ G D +KE A + ++TE Sbjct: 50 FGQIPALEEDDLTLFESRAITSYIAEKFKGTGYDLIRHENLKEAASVKVWTEVESHRYNP 109 Query: 98 GMADLNEMILLLPLCRPEEKDAKIALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRAD 157 +A + ++ PL R D I + + +E L S YL G+ S AD Sbjct: 110 AIAPIVFQFMVAPL-RGNSPDQTIIDDNVEKLGKVLDIYEAKLSS--TKYLAGDFYSLAD 166 Query: 158 ISLVELLYYVEELD-SSLISNFPLLKALKTRISNLPTVKK 196 + + YY+ + +S+++ P +KA IS+ P KK Sbjct: 167 LHHLPYTYYLMKTPAASVVNERPHVKAWWEDISSRPAFKK 206 >2DC5-A nrPDB Length = 231 Score = 49.3 bits (116), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 55/212 (25%), Positives = 95/212 (44%), Gaps = 25/212 (11%) Query: 2 AGKP-KLHYFNGRGRMEPIRWLLAAAGVEFEEK--FIGSAEDLGKLR--NDG---SLMFQ 53 +G P L Y++ RG IR L +EEK +G A D + + N+ L F Sbjct: 6 SGMPMTLGYWDIRGLAHAIRLFLEYTDSSYEEKRYTMGDAPDYDQSQWLNEKFKLGLDFP 65 Query: 54 QVPMVEIDG-MKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLC 112 +P + IDG K+ Q+ AIL Y+ K+NL G+ +ER +D+ + D N M+L LC Sbjct: 66 NLPYL-IDGSHKITQSNAILRYLGRKHNLCGETEEERIRVDILENQLMD-NRMVLAR-LC 122 Query: 113 RPEEKDAKIALIKEKTKSRYFPAFEKVLQSHGQ-----DYLVGNKLSRADISLVELLYYV 167 + EK K Y +++ + + + G+K++ D ++L Sbjct: 123 YNAD--------FEKLKPGYLEQLPGMMRLYSEFLGKRPWFAGDKITFVDFIAYDVLERN 174 Query: 168 EELDSSLISNFPLLKALKTRISNLPTVKKFLQ 199 + ++ + FP LK R L + +++ Sbjct: 175 QVFEAKCLDAFPNLKDFIARFEGLKKISDYMK 206 >4WR5-A nrPDB Length = 244 Score = 49.3 bits (116), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 46/160 (28%), Positives = 72/160 (45%), Gaps = 23/160 (14%) Query: 49 SLMFQQVPMVEIDG-MKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMIL 107 L F +P IDG +KL Q+ AI+ IA K+N+ G KERA I M + D+ + Sbjct: 73 GLEFPNLP-YXIDGDVKLTQSMAIIRXIADKHNMLGGCPKERAEISMLEGAVLDIRYGV- 130 Query: 108 LLPLCRPEEKDAKIALIK--EKTKSRYFPAFEKVLQ------SHGQDYLVGNKLSRADIS 159 ++IA K E K + ++L+ H + L G+ ++ D Sbjct: 131 -----------SRIAYSKDFETLKVDFLSKLPEMLKMFEDRLCH-KTXLNGDHVTHPDFM 178 Query: 160 LVELLYYVEELDSSLISNFPLLKALKTRISNLPTVKKFLQ 199 L + L V +D + FP L K RI +P + K+L+ Sbjct: 179 LYDALDVVLXMDPMCLDAFPKLVCFKKRIEAIPQIDKYLK 218 >4RI7-A nrPDB Length = 215 Score = 43.5 bits (101), Expect = 8e-05, Method: Compositional matrix adjust. Identities = 51/165 (30%), Positives = 72/165 (43%), Gaps = 24/165 (14%) Query: 52 FQQVPMVEIDGMKLVQTRAILNYIASKY------NLYGKDIKERALIDMYTEG------- 98 F QVP + + + L ++RAI YI KY +LYG DI +A ID + E Sbjct: 53 FGQVPAFKDESITLFESRAICRYICDKYADKGNKSLYGTDILSKANIDQWVETDGQTFGP 112 Query: 99 -MADLNEMILLLPLCRPEEKDAKIALIKEKTKSRYFPAFEKVLQSHGQD-YLVGNKLSRA 156 DL +L + E ALIK K + + Q GQ +L G++ S A Sbjct: 113 PSGDLVHDLLFSSVPVDE------ALIK-KNVDKLAKVLDIYEQKLGQTRFLAGDEFSFA 165 Query: 157 DIS-LVELLYYVEELDSS-LISNFPLLKALKTRISNLPTVKKFLQ 199 D+S L Y V D L ++ + T ISN + KK L+ Sbjct: 166 DLSHLPNGDYLVNSTDKGYLFTSRKNVNRWWTEISNRESWKKVLE 210 >1GSU-A nrPDB Length = 219 Score = 42.7 bits (99), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 54/219 (24%), Positives = 93/219 (42%), Gaps = 34/219 (15%) Query: 7 LHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSA-------EDLGKLRNDGSLMFQQVPMVE 59 L Y++ RG IR LL ++E+ + D + L F +P + Sbjct: 4 LGYWDIRGLAHAIRLLLEYTETPYQERRYKAGPAPDFDPSDWTNEKEKLGLDFPNLPYL- 62 Query: 60 IDG-MKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLC-RPEEK 117 IDG +KL Q+ AIL YIA K+N+ G+ E+ +D+ + DL + LC P+ + Sbjct: 63 IDGDVKLTQSNAILRYIARKHNMCGETEVEKQRVDVLENHLMDLR--MAFARLCYSPDFE 120 Query: 118 DAKIALIKE-----KTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDS 172 K A +++ + SR+ + + + VG+KL+ D L Y V + Sbjct: 121 KLKPAYLEQLPGKLRQLSRFLGS---------RSWFVGDKLTFVDF----LAYDVLDQQR 167 Query: 173 SLISNFPLLKA----LKTRISNLPTVKKFLQPGSPRKPP 207 + + P L+ R L + +++ G K P Sbjct: 168 MFVPDCPELQGNLSQFLQRFEALEKISAYMRSGRFMKAP 206 >3VWX-A nrPDB Length = 222 Score = 41.6 bits (96), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 45/151 (29%), Positives = 69/151 (45%), Gaps = 18/151 (11%) Query: 53 QQVPMVEIDGMKLVQTRAILNYIASKY----NLYGKDIKERALID--MYTEGMADLNEMI 106 VP +E DG + + AI+ Y+ SKY +LY KD+ +RA++D MY E + Sbjct: 53 HTVPTLEEDGHLIWDSHAIMAYLVSKYGKDDSLYPKDLLKRAVVDQRMYFEAGVLFQGGL 112 Query: 107 --LLLPLCRPEEKDAKIALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISL---V 161 + PL + I +S F E L+++ Y+ G+ L+ AD S+ V Sbjct: 113 RNITAPLFFRNQTQIPQHQIDSIVESYGF--LESFLKNN--KYMAGDHLTIADFSIVTSV 168 Query: 162 ELLYYVEELDSSLISNFPLLKALKTRISNLP 192 L E+D S FP L A + +LP Sbjct: 169 TSLVAFAEIDQ---SKFPKLSAWLKSLQSLP 196 >5F0G-A nrPDB Length = 215 Score = 41.2 bits (95), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 48/187 (25%), Positives = 83/187 (44%), Gaps = 27/187 (14%) Query: 7 LHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAE------DLGKLRNDGSLMFQQVPMVEI 60 +Y G G + + A G+E +K + + E + KL +P + Sbjct: 3 FYYMPGGGGCRTVIMVAKALGLELNKKLLNTMEGEQLKPEFVKLNPQ-----HTIPTLVD 57 Query: 61 DGMKLVQTRAILNYIASKYN----LYGKDIKERALID--MYTEGMADLNEMI--LLLPLC 112 +G + ++RAI Y+ KY L D K+RA+I+ +Y + M L E PL Sbjct: 58 NGFSIWESRAIAVYLVEKYGKDDYLLPNDPKKRAVINQRLYFD-MGTLYESFAKYYYPLF 116 Query: 113 RPEEKDAKIALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELL--YYVEEL 170 R + + L + +T + F GQ+Y+ G++L+ ADI+++ + + V E Sbjct: 117 RTGKPGSDEDLKRIETAFGFLDTF-----LEGQEYVAGDQLTVADIAILSTVSTFEVSEF 171 Query: 171 DSSLISN 177 D S SN Sbjct: 172 DFSKYSN 178 >3LSZ-A nrPDB Length = 225 Score = 38.5 bits (88), Expect = 0.002, Method: Compositional matrix adjust. Identities = 40/155 (25%), Positives = 70/155 (45%), Gaps = 13/155 (8%) Query: 54 QVPMVEIDGMKLVQTRAILNYIASKYN--LYGKDIKERALIDMYTEGMADLNE------- 104 Q+P +E +G+ L ++ AI +IA L + E AL+ ++ A E Sbjct: 63 QIPCLEEEGLILTESLAITLHIARTQGGQLGPRSEPEDALMVSWSLFAATAVEPPALEIQ 122 Query: 105 MILLLPLCRPEEKDAKIALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELL 164 +I E A IA+ E+ + R E+ + +DYLVG + + AD++L E L Sbjct: 123 LIQRSGGGTSPEGQAAIAIAAERLR-RPLARLERHFAA--EDYLVGGRFTVADLNLAETL 179 Query: 165 YYVEELDSSLISNFPLLKALKTRISNLPTVKKFLQ 199 Y + +L+ FP + A R + P + ++ Sbjct: 180 RY-GQAHPALLEPFPAVAAWLDRCQSRPAFRLMME 213 >1F2E-A nrPDB Length = 201 Score = 38.5 bits (88), Expect = 0.002, Method: Compositional matrix adjust. Identities = 45/155 (29%), Positives = 68/155 (43%), Gaps = 18/155 (11%) Query: 54 QVPMVEID-GMKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILL---- 108 +VP + +D G L + AIL YIA + G E +L D Y L+ + L Sbjct: 51 KVPALTLDSGETLTENPAILLYIADQNPASGLAPAEGSL-DRYRL----LSRLSFLGSEF 105 Query: 109 ----LPLCRPEEKDAKIALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELL 164 +PL P D A E K+ + A +K L G+D+ GN S ADI L +L Sbjct: 106 HKAFVPLFAPATSDEAKAAAAESVKN-HLAALDKELA--GRDHYAGNAFSVADIYLYVML 162 Query: 165 YYVEELDSSLISNFPLLKALKTRISNLPTVKKFLQ 199 + + + + +P L A +I+ P V L+ Sbjct: 163 GWPAYVGIDMAA-YPALGAYAGKIAQRPAVGAALK 196 >5EY6-A nrPDB Length = 217 Score = 38.5 bits (88), Expect = 0.002, Method: Compositional matrix adjust. Identities = 19/52 (36%), Positives = 28/52 (53%), Gaps = 6/52 (11%) Query: 52 FQQVPMVEIDGMKLVQTRAILNYIASKY------NLYGKDIKERALIDMYTE 97 F QVP + + + L ++R+I Y+ KY LYG + ERA ID + E Sbjct: 52 FGQVPAFQDESISLFESRSICRYVCEKYADRGDKGLYGTNPLERASIDQWVE 103 >3M8N-A nrPDB Length = 225 Score = 37.7 bits (86), Expect = 0.004, Method: Compositional matrix adjust. Identities = 40/147 (27%), Positives = 69/147 (46%), Gaps = 12/147 (8%) Query: 54 QVPMVEID-GMKLVQTRAILNYIASKYNLYGKDIKERA--LIDMYTEGMA---DLNEMIL 107 QVP++E G L ++ AIL Y+A +L +RA L M+ E A ++ Sbjct: 54 QVPLLETAPGRYLAESNAILWYLAVGTSLAPDTRMDRAEALQWMFFEQHALEPNIGSAYF 113 Query: 108 LLPLCRPEEKDAKIALIKEKTKSRYFPAFEKVLQSH--GQDYLVGNKLSRADISLVELLY 165 L L + +D + +++ + Y A +V+++H DY +L+ ADI+L + Sbjct: 114 WLCLVK-GGRDLQTHALEDWLERGY--AALQVMENHLKTNDYFAAGQLTIADIALYGYTH 170 Query: 166 YVEELDSSLISNFPLLKALKTRISNLP 192 ++ D L S FP + A R+ P Sbjct: 171 VADQCDFDL-STFPAVNAWLRRVEQTP 196 >1PN9-A nrPDB Length = 209 Score = 35.8 bits (81), Expect = 0.014, Method: Compositional matrix adjust. Identities = 56/207 (27%), Positives = 83/207 (40%), Gaps = 39/207 (18%) Query: 7 LHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMF-----QQVPMVEID 61 +Y G ++ AA GVE K DL K + +P + + Sbjct: 3 FYYLPGSAPCRAVQMTAAAVGVELNLKLT----DLMKGEHMKPEFLKLNPQHCIPTLVDN 58 Query: 62 GMKLVQTRAILNYIASKYN----LYGKDIKERALI------DMYT--EGMADLN-EMILL 108 G L ++RAI Y+A KY LY KD ++RA++ DM T + AD + I Sbjct: 59 GFALWESRAIQIYLAEKYGKDDKLYPKDPQKRAVVNQRLYFDMGTLYQRFADYHYPQIFA 118 Query: 109 LPLCRPEEKDAKIALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELL--YY 166 PE + K K + F + GQ+Y GN L+ AD+SL + Y Sbjct: 119 KQPANPENEK------KMKDAVGFLNTFLE-----GQEYAAGNDLTIADLSLAATIATYE 167 Query: 167 VEELDSSLISNFPLLKALKTRI-SNLP 192 V D + +P + A R +N P Sbjct: 168 VAGFD---FAPYPNVAAWFARCKANAP 191 >1AW9-A nrPDB Length = 216 Score = 35.8 bits (81), Expect = 0.015, Method: Compositional matrix adjust. Identities = 46/169 (27%), Positives = 79/169 (46%), Gaps = 17/169 (10%) Query: 52 FQQVPMVEIDGMK-LVQTRAILNYIASKYNLYGKDI----KERALIDMYTEGMA-----D 101 F Q+P + +DG + L ++RAI YIASKY G D+ A ++++ E + + Sbjct: 51 FGQIPAL-VDGDEVLFESRAINRYIASKYASEGTDLLPATASAAKLEVWLEVESHHFYPN 109 Query: 102 LNEMILLLPLCRPEEKDAKIALIKEKTKSRYFPAFEKVLQSH--GQDYLVGNKLSRADIS 159 + ++ L L RP A A + +K + + V ++H YL G++ + AD + Sbjct: 110 ASPLVFQL-LVRPLLGGAPDAAVVDKHAEQLAKVLD-VYEAHLARNKYLAGDEFTLADAN 167 Query: 160 LVE-LLYYVEELDSSLISNFPLLKALKTRISNLPTVKKFLQPGSPRKPP 207 LLY + + L++ P +KA I P +K + P PP Sbjct: 168 HASYLLYLSKTPKAGLVAARPHVKAWWEAIVARPAFQKTVA-AIPLPPP 215 >1AXD-A nrPDB Length = 209 Score = 35.4 bits (80), Expect = 0.017, Method: Compositional matrix adjust. Identities = 42/157 (26%), Positives = 75/157 (47%), Gaps = 15/157 (9%) Query: 52 FQQVPMVEIDGMKLVQTRAILNYIASKYN---LYGKDIKERALIDMYTEGMAD-----LN 103 F QVP ++ + L ++RAI Y A K L +++E A++D++ E A+ LN Sbjct: 51 FGQVPALQDGDLYLFESRAICKYAARKNKPELLREGNLEEAAMVDVWIEVEANQYTAALN 110 Query: 104 EM---ILLLPLCRPEEKDAKIALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISL 160 + +L+ P+ + EK K + +E L YL G+ LS AD++ Sbjct: 111 PILFQVLISPMLGGTTDQKVVDENLEKLK-KVLEVYEARLTK--CKYLAGDFLSLADLNH 167 Query: 161 VEL-LYYVEELDSSLISNFPLLKALKTRISNLPTVKK 196 V + L +S++ +P +KA + + P+V+K Sbjct: 168 VSVTLCLFATPYASVLDAYPHVKAWWSGLMERPSVQK 204 >2GDR-A nrPDB Length = 202 Score = 35.4 bits (80), Expect = 0.019, Method: Compositional matrix adjust. Identities = 51/209 (24%), Positives = 93/209 (44%), Gaps = 29/209 (13%) Query: 6 KLHYFNGRGRMEPIRWLLAAAGVEFE-------EKFIGSAEDLGKLRNDGSLMFQQVPMV 58 KL+Y G + P L AG+ FE K S +D ++ G VP + Sbjct: 2 KLYYSPGACSLSP-HIALREAGLNFELVQVDLASKKTASGQDYLEVNPAG-----YVPCL 55 Query: 59 EID-GMKLVQTRAILNYIASKYNLYGKDIK------ERALIDMYTEGMA-DLNEMILLLP 110 ++D G L + AI+ Y+A + + GK + ER + + ++ +L++ P Sbjct: 56 QLDDGRTLTEGPAIVQYVADQ--VPGKQLAPANGSFERYHLQQWLNFISSELHKS--FSP 111 Query: 111 LCRPEEKDAKIALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEEL 170 L P D +++ +R ++ + YL+G++LS ADI L +L + + Sbjct: 112 LFNPASSDEWKNAVRQSLNTRLGQVARQLEHA---PYLLGDQLSVADIYLFVVLGWSAYV 168 Query: 171 DSSLISNFPLLKALKTRISNLPTVKKFLQ 199 + L S +P L+A + R+ V+ L+ Sbjct: 169 NIDL-SPWPSLQAFQGRVGGREAVQSALR 196 >3MAK-A nrPDB Length = 209 Score = 33.9 bits (76), Expect = 0.056, Method: Compositional matrix adjust. Identities = 35/119 (29%), Positives = 53/119 (44%), Gaps = 18/119 (15%) Query: 53 QQVPMVEIDGMKLVQTRAILNYIASKY----NLYGKDIKERALI------DMYTEGMADL 102 +P + +G L ++RAI Y+ KY +LY K K+RA+I DM T + Sbjct: 51 HTIPTLVDNGFALWESRAIQVYLVEKYGKTDSLYPKCPKKRAVINQRLYFDMGTLYQSFA 110 Query: 103 NEMILLLPLCRPEEKDAKIALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLV 161 N + P + +A K + + F GQDY G+ L+ ADI+LV Sbjct: 111 NYYYPQVFAKAPADPEA---FKKIEAAFEFLNTF-----LEGQDYAAGDSLTVADIALV 161 >3GH6-A nrPDB Length = 210 Score = 33.1 bits (74), Expect = 0.086, Method: Compositional matrix adjust. Identities = 26/93 (27%), Positives = 46/93 (49%), Gaps = 6/93 (6%) Query: 7 LHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQ--VPMVEIDGMK 64 L+Y G + A GVEF++K I + + + + Q +P + G Sbjct: 3 LYYRPGSAPCRSVLMTAKALGVEFDKKTIINTRAREQFTPEYLKINPQHTIPTLHDHGFA 62 Query: 65 LVQTRAILNYIASKYN----LYGKDIKERALID 93 L ++RAI+ Y+ KY L+ KD++++ALI+ Sbjct: 63 LWESRAIMVYLVEKYGKDDKLFPKDVQKQALIN 95 >5A5K-A nrPDB Length = 212 Score = 33.1 bits (74), Expect = 0.095, Method: Compositional matrix adjust. Identities = 15/35 (42%), Positives = 21/35 (60%) Query: 52 FQQVPMVEIDGMKLVQTRAILNYIASKYNLYGKDI 86 F QVP E +KL ++RAI YIA +Y G ++ Sbjct: 52 FGQVPAFEDGDLKLFESRAITQYIAHRYENQGTNL 86 >3IBH-A nrPDB Length = 233 Score = 33.1 bits (74), Expect = 0.095, Method: Compositional matrix adjust. Identities = 42/162 (25%), Positives = 74/162 (45%), Gaps = 23/162 (14%) Query: 55 VPMVEID-GMKLVQTRAILNYIAS---KYNLYGKDIKERALIDMYTEGMADLNEMILLLP 110 VP++E+D G + + AI YI + L GK E+ +I M M E+ LL P Sbjct: 72 VPVLELDDGTLIAECTAITEYIDALDGTPTLTGKTPLEKGVIHM----MNKRAELELLDP 127 Query: 111 LC----------RPEEK--DAKIALIKEKTKSRY-FPAFEKVLQSHGQDYLVGNKLSRAD 157 + PE + K ++++ K+ + F+ VL+ + Y+ G+ S AD Sbjct: 128 VSVYFHHATPGLGPEVELYQNKEWGLRQRDKALHGMHYFDTVLRE--RPYVAGDSFSMAD 185 Query: 158 ISLVELLYYVEELDSSLISNFPLLKALKTRISNLPTVKKFLQ 199 I+++ L + + + L+A R+ P+VKK L+ Sbjct: 186 ITVIAGLIFAAIVKLQVPEECEALRAWYKRMQQRPSVKKLLE 227 >1JLV-A nrPDB Length = 209 Score = 33.1 bits (74), Expect = 0.11, Method: Compositional matrix adjust. Identities = 16/43 (37%), Positives = 27/43 (62%), Gaps = 4/43 (9%) Query: 55 VPMVEIDGMKLVQTRAILNYIASKYN----LYGKDIKERALID 93 +P + +G L ++RAI Y+A KY LY KD ++RA+++ Sbjct: 52 IPTLVDNGFALWESRAICTYLAEKYGKDDKLYPKDPQKRAVVN 94 >6F05-A nrPDB Length = 215 Score = 32.7 bits (73), Expect = 0.14, Method: Compositional matrix adjust. Identities = 15/51 (29%), Positives = 29/51 (56%), Gaps = 5/51 (9%) Query: 52 FQQVPMVEIDGMKLVQTRAILNYIASKY-----NLYGKDIKERALIDMYTE 97 F VP V K+ ++RA++ Y+A KY +L GK +++R ++ + + Sbjct: 50 FGTVPAVVDGDYKIFESRAVMRYVAEKYRSQGPDLLGKTVEDRGQVEQWLD 100 >5LOL-A nrPDB Length = 215 Score = 32.3 bits (72), Expect = 0.17, Method: Compositional matrix adjust. Identities = 27/115 (23%), Positives = 50/115 (43%), Gaps = 11/115 (9%) Query: 54 QVPMVEIDGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCR 113 +VP+V++DG + + I+ + KY + + + + G + L Sbjct: 61 KVPVVKLDGKWVADSDVIVGLLEEKY----PEPSLKTPPEFASVGSKIFGAFVTFL---- 112 Query: 114 PEEKDAKIALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVE 168 + KDA EK A E L++H ++ G K++ D+SL LY++E Sbjct: 113 -KSKDANDG--SEKALVDELEALENHLKTHSGPFVAGEKITAVDLSLAPKLYHLE 164 >3M3M-A nrPDB Length = 210 Score = 32.0 bits (71), Expect = 0.19, Method: Compositional matrix adjust. Identities = 40/156 (25%), Positives = 67/156 (42%), Gaps = 13/156 (8%) Query: 54 QVPMVEI-DGMKLVQTRAILNYIASKYNLYGKDIKERALI------DMYT-EGMADLNEM 105 ++P++E+ DG L ++ AILN++A + + R + + Y+ E + Sbjct: 54 KIPVLELEDGTCLWESNAILNFLADGSQFLPSEPRLRTQVLQWQFFEQYSHEPYIAVARF 113 Query: 106 ILLLPLCRPEEKDAKIALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLY 165 I L E ++ + L K K+ EK L YLVG S ADI+L + Sbjct: 114 IQLYEGLPEERREEYLKLHKRGYKA--LDVMEKQLSR--TPYLVGEHYSIADIALYAYTH 169 Query: 166 YVEELDSSLISNFPLLKALKTRISNLPTVKKFLQPG 201 +E L S +P ++A R+ + P L G Sbjct: 170 VADEGGFDL-SRYPGIQAWMQRVQSHPRHVPMLDEG 204 >3UBL-A nrPDB Length = 242 Score = 32.0 bits (71), Expect = 0.21, Method: Compositional matrix adjust. Identities = 44/182 (24%), Positives = 83/182 (45%), Gaps = 14/182 (7%) Query: 6 KLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSA--EDLGKLRNDGSLMFQQVPMVEIDGM 63 KLH + + ++ + G+E+E+ I + ED K+ G ++P++E+DG Sbjct: 5 KLHGASISNYVNKVKLGILEKGLEYEQIRIAPSQEEDFLKISPMG-----KIPVLEMDGK 59 Query: 64 KLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAKIA- 122 + ++ AIL ++ + + K I E ++ + E L +P R AK++ Sbjct: 60 FIFESGAILEFLDTIFPQTPKLIPEDPWEAARVREISTIIETYLDIPARRIYLPAAKVSP 119 Query: 123 -LIKE--KTKSRYFPAFEKVLQSHGQDYLVGNKLSRADIS-LVELLYYVEELDSSLISNF 178 +++E T + A ++V++ Y+ GN + AD S L EEL +N Sbjct: 120 EIVEEVHSTLVKGIKALQRVVRF--SPYIAGNVFTLADCSGFAHLSVLDEELRPFYPNNH 177 Query: 179 PL 180 PL Sbjct: 178 PL 179 >3PPU-A nrPDB Length = 352 Score = 32.0 bits (71), Expect = 0.21, Method: Compositional matrix adjust. Identities = 22/68 (32%), Positives = 36/68 (52%), Gaps = 6/68 (8%) Query: 137 EKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLISNFPL-LKALKTRISNLPTVK 195 EK+L+ GQDYL+G +L+ ADI L + D +++F L+ ++ NL Sbjct: 249 EKMLE--GQDYLIGGQLTEADI---RLFVTIVRFDPVYVTHFKCNLRTIRDGYPNLHRWM 303 Query: 196 KFLQPGSP 203 + L G+P Sbjct: 304 RKLYWGNP 311 >4FQU-A nrPDB Length = 313 Score = 31.6 bits (70), Expect = 0.26, Method: Compositional matrix adjust. Identities = 22/84 (26%), Positives = 43/84 (51%), Gaps = 10/84 (11%) Query: 119 AKIALIKEKTKSRYFPAFEKV--LQSH--GQDYLVGNKLSRADISLVELLYYVEELDSSL 174 + A +E + ++P F+ + L+ H G+++LVG++L+ ADI L L D+ Sbjct: 186 SGFATTQEAYEEAFYPLFDTLDWLEEHLTGREWLVGDRLTEADIRLFPTLV---RFDAIY 242 Query: 175 ISNFPLLKALKTRISNLPTVKKFL 198 +F K RI++ P + + + Sbjct: 243 HGHF---KCNLRRIADYPNLSRLV 263 >3LG6-A nrPDB Length = 235 Score = 31.2 bits (69), Expect = 0.34, Method: Compositional matrix adjust. Identities = 16/53 (30%), Positives = 31/53 (58%), Gaps = 1/53 (1%) Query: 130 SRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLISNFPLLK 182 ++ F A EK+L+ + VG++++ AD+ LV ++ E + L + FP+ K Sbjct: 155 TQGFGAVEKLLELSAGRFCVGDEITLADVCLVPAVWAAERVGMDL-ARFPITK 206 >5WTZ-A nrPDB Length = 421 Score = 30.8 bits (68), Expect = 0.42, Method: Compositional matrix adjust. Identities = 18/65 (27%), Positives = 34/65 (52%), Gaps = 1/65 (1%) Query: 40 DLGKLRNDGSLMFQQVPMVEIDGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGM 99 D K +N +L ++ V ++ + ++ +I NYI + + IK++ +D Y EG+ Sbjct: 11 DFAKDKNSATLWAKKRKQVWLNNLSKAESTSINNYIKNSSEINSYSIKKKFALDNY-EGI 69 Query: 100 ADLNE 104 LNE Sbjct: 70 ETLNE 74 >4G0L-A nrPDB Length = 328 Score = 29.6 bits (65), Expect = 0.98, Method: Compositional matrix adjust. Identities = 22/63 (34%), Positives = 32/63 (50%), Gaps = 8/63 (12%) Query: 137 EKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLISNFPLLKALKTRISNLPTVKK 196 E++L H YL GN+L+ ADI L L D +++F K K RIS+ + Sbjct: 221 EQILGQH--RYLTGNQLTEADIRLWTTLV---RFDPVYVTHF---KCDKHRISDYLNLYG 272 Query: 197 FLQ 199 FL+ Sbjct: 273 FLR 275 >6GCB-A nrPDB Length = 325 Score = 29.6 bits (65), Expect = 1.2, Method: Compositional matrix adjust. Identities = 20/63 (31%), Positives = 33/63 (52%), Gaps = 7/63 (11%) Query: 137 EKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLISNFPLLKALKTRISNLPTVKK 196 EK+L G+DYLVG++L+ AD V L + D + + +F L+T P + Sbjct: 219 EKILT--GKDYLVGDQLTEAD---VRLFVTIIRFDPAYVGHFKC--NLRTIRDGYPAIHL 271 Query: 197 FLQ 199 +L+ Sbjct: 272 WLR 274 >6FFY-A nrPDB Length = 972 Score = 29.3 bits (64), Expect = 1.3, Method: Composition-based stats. Identities = 16/58 (27%), Positives = 27/58 (46%), Gaps = 7/58 (12%) Query: 86 IKERALIDMYTEGMADLNEMILLLPLCRPEEKDAKIALIKEKTKSRYFPAFEKVLQSH 143 I E L+ + G+ + ++ +LLPL RP K + T + A ++ L SH Sbjct: 884 IPEELLVTVVKPGLPTIADLYVLLPLPRPTRK-------RSLTSDKRLAAVQQALNSH 934 >6GC9-A nrPDB Length = 327 Score = 29.3 bits (64), Expect = 1.5, Method: Compositional matrix adjust. Identities = 14/24 (58%), Positives = 19/24 (79%), Gaps = 2/24 (8%) Query: 137 EKVLQSHGQDYLVGNKLSRADISL 160 EK+L G+DYLVG++L+ ADI L Sbjct: 220 EKILT--GKDYLVGDQLTEADIRL 241 >5ELG-A nrPDB Length = 221 Score = 28.9 bits (63), Expect = 1.8, Method: Compositional matrix adjust. Identities = 12/34 (35%), Positives = 21/34 (61%) Query: 135 AFEKVLQSHGQDYLVGNKLSRADISLVELLYYVE 168 A E L+SH ++ G ++S D+SL LY+++ Sbjct: 129 ALENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQ 162 >5F05-A nrPDB Length = 212 Score = 28.5 bits (62), Expect = 2.4, Method: Compositional matrix adjust. Identities = 15/36 (41%), Positives = 22/36 (61%), Gaps = 2/36 (5%) Query: 52 FQQVPMVEIDG-MKLVQTRAILNYIASKYNLYGKDI 86 F QVP +DG +KL ++RAI Y+A +Y G + Sbjct: 51 FGQVPAA-VDGDLKLFESRAISQYVAHQYASKGTQL 85 >2C3Q-A nrPDB Length = 247 Score = 28.1 bits (61), Expect = 2.8, Method: Compositional matrix adjust. Identities = 15/48 (31%), Positives = 27/48 (56%), Gaps = 4/48 (8%) Query: 52 FQQVPMVEIDGMKLVQTRAILNYIASKYNL----YGKDIKERALIDMY 95 ++VP ++ L ++ AIL Y+ KY + Y +D++ RA +D Y Sbjct: 58 LKKVPALKDGDFTLTESVAILLYLTRKYKVPDYWYPQDLQARARVDEY 105 >6D84-M nrPDB Length = 423 Score = 27.7 bits (60), Expect = 3.9, Method: Compositional matrix adjust. Identities = 38/158 (24%), Positives = 63/158 (39%), Gaps = 31/158 (19%) Query: 81 LYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAKIALIKEKTKSRYFPAFEKVL 140 +Y D+K + LI G D++E+ +P+ +E++ ++ I R+ + Sbjct: 6 VYVLDLKGKVLICRNYRGDVDMSEVEHFMPILMEKEEEGMLSPILAHGGVRF------MW 59 Query: 141 QSHGQDYLVGNKLSRADISLV-ELLY--------YVEEL-DSSLISNFPLLKALKTRISN 190 H YLV A +SLV LY Y +EL + S+ NF ++ L + + Sbjct: 60 IKHNNLYLVATSKKNACVSLVFSFLYKVVQVFSEYFKELEEESIRDNFVIIYELLDELMD 119 Query: 191 L----PTVKKFLQ-----------PGSPRKPPADAKAL 213 T K LQ G+PR P A+ Sbjct: 120 FGYPQTTDSKILQEYITQEGHKLETGAPRPPATVTNAV 157 >5D9W-A nrPDB Length = 230 Score = 27.7 bits (60), Expect = 4.3, Method: Compositional matrix adjust. Identities = 13/34 (38%), Positives = 23/34 (67%), Gaps = 1/34 (2%) Query: 135 AFEKVLQSHGQDYLVGNKLSRADISLVELLYYVE 168 A E+ L++HG ++ G +S AD+SL LY+++ Sbjct: 147 ALEEHLKAHGP-FINGQNISAADLSLAPKLYHLQ 179 >5DXT-A nrPDB Length = 962 Score = 27.3 bits (59), Expect = 4.7, Method: Compositional matrix adjust. Identities = 18/43 (41%), Positives = 27/43 (62%), Gaps = 1/43 (2%) Query: 145 QDYLVGNKLSRADISLVELLYYVEELDSSLISNFPLLKALKTR 187 + YL +KLS+ I LV++L Y + LD+ L+ F L KAL + Sbjct: 514 EKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVR-FLLKKALTNQ 555 >4UY5-A nrPDB Length = 329 Score = 27.3 bits (59), Expect = 4.8, Method: Compositional matrix adjust. Identities = 19/53 (35%), Positives = 26/53 (49%), Gaps = 1/53 (1%) Query: 12 GRGRMEPIRWLLAAA-GVEFEEKFIGSAEDLGKLRNDGSLMFQQVPMVEIDGM 63 G G E R LL A E +FI D G LR+ G+ + + P +EID + Sbjct: 86 GSGTSEKTRMLLDAMRDAELLRRFIPFDVDAGVLRSAGAAIGAEYPGIEIDAV 138 >3AYF-A nrPDB Length = 800 Score = 27.3 bits (59), Expect = 5.4, Method: Composition-based stats. Identities = 25/94 (26%), Positives = 40/94 (42%), Gaps = 7/94 (7%) Query: 60 IDGMKLVQTRAILNY--IASKYNLYGKDIKERALIDMYTEGMADLNEMIL----LLPLCR 113 I G + Q +++Y + + G D AL +YTEGM D L Sbjct: 70 IGGQAVFQKYGLMDYGTVLGHGSYMGPDYTAEAL-KVYTEGMQDYKAKERYNKPFADLTD 128 Query: 114 PEEKDAKIALIKEKTKSRYFPAFEKVLQSHGQDY 147 E+ + +IKE K+RY P + ++ + Q Y Sbjct: 129 DEKSIIREQVIKEMRKNRYNPVTDVLVLTDAQVY 162 >3FD5-A nrPDB Length = 394 Score = 27.3 bits (59), Expect = 5.6, Method: Compositional matrix adjust. Identities = 14/48 (29%), Positives = 24/48 (50%) Query: 62 GMKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLL 109 G+ LVQT + I + G+ L D+Y G+ + + M++LL Sbjct: 81 GLSLVQTTDYIYPIVDDPYMMGRIACANVLSDLYAMGVTECDNMLMLL 128 >5UDD-A nrPDB Length = 568 Score = 26.9 bits (58), Expect = 7.8, Method: Compositional matrix adjust. Identities = 25/76 (32%), Positives = 34/76 (44%), Gaps = 8/76 (10%) Query: 135 AFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELD------SSLISN--FPLLKALKT 186 A KVL G+ + N L + ++V L V L S I+N P+L Sbjct: 153 AVCKVLHLEGEVNKIKNALLSTNKAVVSLSNGVSVLTFKVLDLKSYINNQLLPILNQQSC 212 Query: 187 RISNLPTVKKFLQPGS 202 RISN+ TV +F Q S Sbjct: 213 RISNIETVIEFQQKNS 228 >2IL3-A nrPDB Length = 221 Score = 26.6 bits (57), Expect = 7.9, Method: Compositional matrix adjust. Identities = 12/45 (26%), Positives = 28/45 (62%), Gaps = 4/45 (8%) Query: 53 QQVPMVEIDGMKLVQTRAILNYIASKY----NLYGKDIKERALID 93 +P+++ +G + ++ AI+ Y+ +KY +LY KD ++A ++ Sbjct: 53 HTIPVLDDNGTIITESHAIMIYLVTKYGKDDSLYPKDPVKQARVN 97 >1G6W-A nrPDB Length = 261 Score = 26.6 bits (57), Expect = 8.0, Method: Compositional matrix adjust. Identities = 22/95 (23%), Positives = 43/95 (45%), Gaps = 3/95 (3%) Query: 108 LLPLCRPEEKDAKIALIKEKTKSRYFPAFEKVLQSHGQDY---LVGNKLSRADISLVELL 164 ++ + E ++A + + + + Y + QS DY LVG+KL+ AD++ V Sbjct: 165 VVEMALAERREALVMELDTENAAAYSAGTTPMSQSRFFDYPVWLVGDKLTIADLAFVPWN 224 Query: 165 YYVEELDSSLISNFPLLKALKTRISNLPTVKKFLQ 199 V+ + ++ FP + + P V K L+ Sbjct: 225 NVVDRIGINIKIEFPEVYKWTKHMMRRPAVIKALR 259 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 2VCV-A nrPDB 312 8e-86 3I6A-A nrPDB 301 2e-82 1PL2-A nrPDB 299 6e-82 2VCT-A nrPDB 296 6e-81 1F3B-A nrPDB 291 1e-79 5LCZ-A nrPDB 287 3e-78 1B48-A nrPDB 279 8e-76 1VF1-A nrPDB 275 9e-75 1EV4-A nrPDB 275 1e-74 1GUL-A nrPDB 257 4e-69 3GTU-B nrPDB 234 2e-62 1XWK-A nrPDB 227 3e-60 5FWG-A nrPDB 226 8e-60 4GTU-A nrPDB 223 4e-59 1B4P-A nrPDB 223 4e-59 2DC5-A nrPDB 221 2e-58 5D73-A nrPDB 220 4e-58 2GSR-A nrPDB 218 1e-57 2FHE-A nrPDB 215 8e-57 2GLR-A nrPDB 214 2e-56 1HNA-A nrPDB 214 2e-56 5AN1-A nrPDB 214 3e-56 1GSU-A nrPDB 207 4e-54 18GS-A nrPDB 206 6e-54 4Q5F-A nrPDB 205 9e-54 1TU7-A nrPDB 204 2e-53 4Q5R-A nrPDB 203 6e-53 3KXO-A nrPDB 201 2e-52 1FHE-A nrPDB 197 3e-51 4Q5Q-A nrPDB 197 3e-51 2AAW-A nrPDB 197 4e-51 1GSQ-A nrPDB 196 8e-51 1ZL9-A nrPDB 194 2e-50 2WRT-A nrPDB 194 3e-50 1B8X-A nrPDB 192 8e-50 5Y9Z-A nrPDB 190 3e-49 1DUG-A nrPDB 190 3e-49 1BG5-A nrPDB 190 4e-49 1M0U-A nrPDB 187 5e-48 1YQ1-A nrPDB 182 1e-46 4WR5-A nrPDB 181 2e-46 2WDU-A nrPDB 174 2e-44 2CA8-A nrPDB 173 5e-44 1U3I-A nrPDB 171 2e-43 2HNL-A nrPDB 166 7e-42 2CZ2-A nrPDB 160 5e-40 1FW1-A nrPDB 157 3e-39 5F07-A nrPDB 125 1e-29 4PNG-A nrPDB 124 3e-29 3VWX-A nrPDB 115 1e-26 4YH2-A nrPDB 114 2e-26 5F06-A nrPDB 111 2e-25 5F0G-A nrPDB 104 3e-23 4RI7-A nrPDB 104 3e-23 Sequences not found previously or not previously below threshold: 5EY6-A nrPDB 108 3e-24 1AXD-A nrPDB 100 5e-22 1PN9-A nrPDB 98 3e-21 1JLV-A nrPDB 96 1e-20 6F05-A nrPDB 94 4e-20 5ZWP-A nrPDB 94 5e-20 1AW9-A nrPDB 93 7e-20 3MAK-A nrPDB 93 8e-20 2IL3-A nrPDB 93 9e-20 1E6B-A nrPDB 90 7e-19 5A5K-A nrPDB 84 4e-17 4IGJ-A nrPDB 84 5e-17 5F05-A nrPDB 80 7e-16 4MPF-A nrPDB 80 8e-16 1V2A-A nrPDB 79 2e-15 3LSZ-A nrPDB 79 2e-15 3GH6-A nrPDB 78 3e-15 3M8N-A nrPDB 77 6e-15 3M3M-A nrPDB 76 2e-14 2C3Q-A nrPDB 75 3e-14 3UAR-A nrPDB 75 3e-14 3UBL-A nrPDB 71 3e-13 3LFL-A nrPDB 70 1e-12 2PMT-A nrPDB 68 3e-12 3IBH-A nrPDB 68 4e-12 4PXO-A nrPDB 68 4e-12 2GDR-A nrPDB 66 1e-11 4MDC-A nrPDB 65 2e-11 1F2E-A nrPDB 65 2e-11 4J2F-A nrPDB 65 3e-11 3TOT-A nrPDB 64 5e-11 3LG6-A nrPDB 64 6e-11 3NIV-A nrPDB 63 9e-11 3PR8-A nrPDB 62 2e-10 5ELG-A nrPDB 62 2e-10 3C8E-A nrPDB 61 5e-10 5LOL-A nrPDB 61 5e-10 4MK3-A nrPDB 60 8e-10 2JL4-A nrPDB 60 9e-10 4QQ7-A nrPDB 60 1e-09 4CHS-A nrPDB 59 1e-09 5NR1-A nrPDB 58 3e-09 5F8B-A nrPDB 58 3e-09 3GX0-A nrPDB 57 5e-09 2PVQ-A nrPDB 57 6e-09 2VO4-A nrPDB 56 1e-08 4IKH-A nrPDB 55 3e-08 5J5N-A nrPDB 53 1e-07 5ECL-B nrPDB 52 2e-07 3PPU-A nrPDB 52 2e-07 6JWK-A nrPDB 51 4e-07 5N9U-A nrPDB 51 4e-07 4PQI-A nrPDB 48 3e-06 3RBT-A nrPDB 48 4e-06 4BVY-B nrPDB 47 6e-06 6GC9-A nrPDB 47 8e-06 1N2A-A nrPDB 46 2e-05 1G6W-A nrPDB 45 2e-05 6GCB-A nrPDB 45 2e-05 4FQU-A nrPDB 44 4e-05 5IQY-A nrPDB 43 7e-05 3BBY-A nrPDB 43 8e-05 4G0L-A nrPDB 42 2e-04 1GWC-A nrPDB 42 3e-04 4USS-A nrPDB 40 7e-04 6GZF-A nrPDB 39 0.001 4PTS-A nrPDB 37 0.008 2JZR-A nrPDB 36 0.011 3M1G-A nrPDB 35 0.021 3FY7-A nrPDB 34 0.039 2C5J-A nrPDB 33 0.11 4LMW-A nrPDB 33 0.12 4XRU-B nrPDB 32 0.18 2H30-A nrPDB 32 0.20 5Y7I-A nrPDB 31 0.33 5LKB-A nrPDB 31 0.37 2YV7-A nrPDB 31 0.39 3H2Z-A nrPDB 31 0.44 3QAO-A nrPDB 31 0.47 4K0G-A nrPDB 30 0.74 1OYJ-A nrPDB 29 1.6 2OCA-A nrPDB 29 1.8 2JB2-A nrPDB 29 2.0 4CZI-A nrPDB 29 2.2 3H6J-A nrPDB 28 2.7 5C8D-A nrPDB 28 3.6 5CJH-A nrPDB 28 4.0 2D2Z-A nrPDB 27 8.2 >2VCV-A nrPDB Length = 222 Score = 312 bits (800), Expect = 8e-86, Method: Composition-based stats. Identities = 222/222 (100%), Positives = 222/222 (100%) Query: 1 MAGKPKLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQVPMVEI 60 MAGKPKLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQVPMVEI Sbjct: 1 MAGKPKLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQVPMVEI 60 Query: 61 DGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAK 120 DGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAK Sbjct: 61 DGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAK 120 Query: 121 IALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLISNFPL 180 IALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLISNFPL Sbjct: 121 IALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLISNFPL 180 Query: 181 LKALKTRISNLPTVKKFLQPGSPRKPPADAKALEEARKIFRF 222 LKALKTRISNLPTVKKFLQPGSPRKPPADAKALEEARKIFRF Sbjct: 181 LKALKTRISNLPTVKKFLQPGSPRKPPADAKALEEARKIFRF 222 >3I6A-A nrPDB Length = 222 Score = 301 bits (770), Expect = 2e-82, Method: Composition-based stats. Identities = 192/221 (86%), Positives = 200/221 (90%) Query: 1 MAGKPKLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQVPMVEI 60 MA KPKLHYFNGRGRME RWLLAAAGVEFEEKFI SAEDL KLRNDG LMFQQVPMVEI Sbjct: 1 MAEKPKLHYFNGRGRMESTRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEI 60 Query: 61 DGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAK 120 DGMKLVQTRAILNYIASKYNLYGKDIKERALIDMY EG+ADL EMI++LP C PEEKDAK Sbjct: 61 DGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYIEGIADLGEMIIMLPFCPPEEKDAK 120 Query: 121 IALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLISNFPL 180 +ALIKEK K+RYFPAFEKVL+SHGQDYLVGNKLSRADI LVELLYYVEELDSSLIS+FPL Sbjct: 121 LALIKEKIKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPL 180 Query: 181 LKALKTRISNLPTVKKFLQPGSPRKPPADAKALEEARKIFR 221 LKALKTRISNLPTVKKFLQPGSPRKPP D + IFR Sbjct: 181 LKALKTRISNLPTVKKFLQPGSPRKPPPDEIYVRTVYNIFR 221 >1PL2-A nrPDB Length = 222 Score = 299 bits (766), Expect = 6e-82, Method: Composition-based stats. Identities = 200/222 (90%), Positives = 207/222 (93%) Query: 1 MAGKPKLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQVPMVEI 60 MA KPKLHYFN RGRME RWLLAAAGVEFEEKFI SAEDL KLRNDG LMFQQVPMVEI Sbjct: 1 MAEKPKLHYFNARGRMESTRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEI 60 Query: 61 DGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAK 120 DGMKLVQ RAILNYIASKYNLYGKDIKERALIDMY EG+ADL EMILLLP+C PEEKDAK Sbjct: 61 DGMKLVQERAILNYIASKYNLYGKDIKERALIDMYIEGIADLGEMILLLPVCPPEEKDAK 120 Query: 121 IALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLISNFPL 180 +ALIKEK K+RYFPAFEKVL+SHGQDYLVGNKLSRADI LVELLYYVEELDSSLIS+FPL Sbjct: 121 LALIKEKIKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPL 180 Query: 181 LKALKTRISNLPTVKKFLQPGSPRKPPADAKALEEARKIFRF 222 LKALKTRISNLPTVKKFLQPGSPRKPP D K+LEEARKIFRF Sbjct: 181 LKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEEARKIFRF 222 >2VCT-A nrPDB Length = 222 Score = 296 bits (758), Expect = 6e-81, Method: Composition-based stats. Identities = 197/222 (88%), Positives = 208/222 (93%) Query: 1 MAGKPKLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQVPMVEI 60 MA KPKLHY N RGRME IRWLLAAAGVEFEEKFI SAEDL KLRNDG LMFQQVPMVEI Sbjct: 1 MAEKPKLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEI 60 Query: 61 DGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAK 120 DGMKLVQTRAILNYIASKYNLYGKDIKE+ALIDMY EG+ADL EMILLLP +PEE+DAK Sbjct: 61 DGMKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFTQPEEQDAK 120 Query: 121 IALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLISNFPL 180 +ALI+EKTK+RYFPAFEKVL+SHGQDYLVGNKLSRADI LVELLYYVEELDSSLIS+FPL Sbjct: 121 LALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPL 180 Query: 181 LKALKTRISNLPTVKKFLQPGSPRKPPADAKALEEARKIFRF 222 LKALKTRISNLPTVKKFLQPGSPRKPP D K+LEE+RKIFRF Sbjct: 181 LKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEESRKIFRF 222 >1F3B-A nrPDB Length = 222 Score = 291 bits (746), Expect = 1e-79, Method: Composition-based stats. Identities = 164/221 (74%), Positives = 191/221 (86%) Query: 2 AGKPKLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQVPMVEID 61 AGKP LHYFN RGRME IRWLLAAAGVEFEEKFI S EDL KL+ DG+LMF QVPMVEID Sbjct: 1 AGKPVLHYFNARGRMECIRWLLAAAGVEFEEKFIQSPEDLEKLKKDGNLMFDQVPMVEID 60 Query: 62 GMKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAKI 121 GMKL QTRAILNYIA+KY+LYGKD+KERALIDMY+EG+ DL EMI L LC P++++AK Sbjct: 61 GMKLAQTRAILNYIATKYDLYGKDMKERALIDMYSEGILDLTEMIGQLVLCPPDQREAKT 120 Query: 122 ALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLISNFPLL 181 AL K++TK+RY PAFEKVL+SHGQDYLVGN+L+R DI L+E+L YVEE D+SL++ FPLL Sbjct: 121 ALAKDRTKNRYLPAFEKVLKSHGQDYLVGNRLTRVDIHLLEVLLYVEEFDASLLTPFPLL 180 Query: 182 KALKTRISNLPTVKKFLQPGSPRKPPADAKALEEARKIFRF 222 KA K+RIS+LP VKKFLQPGS RKPP DAK ++EARK F+ Sbjct: 181 KAFKSRISSLPNVKKFLQPGSQRKPPMDAKQIQEARKAFKI 221 >5LCZ-A nrPDB Length = 222 Score = 287 bits (735), Expect = 3e-78, Method: Composition-based stats. Identities = 174/222 (78%), Positives = 197/222 (88%) Query: 1 MAGKPKLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQVPMVEI 60 MA KPKLHYFN RGRME RWLLAAAGVEFEEKFI SAEDL KLRNDG LMFQQVPMVEI Sbjct: 1 MAEKPKLHYFNARGRMESTRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEI 60 Query: 61 DGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAK 120 DGMKLVQTRAILNYIASKYNLYGKD+KERALIDMY+EG+ DL EMI+ L +C P++++AK Sbjct: 61 DGMKLVQTRAILNYIASKYNLYGKDMKERALIDMYSEGILDLTEMIIQLVICPPDQREAK 120 Query: 121 IALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLISNFPL 180 AL K++TK+RY PAFEKVL+SHGQDYLVGN+L+R DI L+ELL YVEE D+SL+++FPL Sbjct: 121 TALAKDRTKNRYLPAFEKVLKSHGQDYLVGNRLTRVDIHLLELLLYVEEFDASLLTSFPL 180 Query: 181 LKALKTRISNLPTVKKFLQPGSPRKPPADAKALEEARKIFRF 222 LKA K+RIS+LP VKKFLQPGS RKP DAK +EEARKIFRF Sbjct: 181 LKAFKSRISSLPNVKKFLQPGSQRKPAMDAKQIEEARKIFRF 222 >1B48-A nrPDB Length = 221 Score = 279 bits (713), Expect = 8e-76, Method: Composition-based stats. Identities = 135/221 (61%), Positives = 170/221 (76%) Query: 2 AGKPKLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQVPMVEID 61 A KPKL+YFNGRGRME IRWLLAAAGVEFEE+F+ + E K++ DG L+F QVP+VEID Sbjct: 1 AAKPKLYYFNGRGRMESIRWLLAAAGVEFEEEFLETREQYEKMQKDGHLLFGQVPLVEID 60 Query: 62 GMKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAKI 121 GM L QTRAIL+Y+A+KYNLYGKD+KER IDMY +G DL MI + P P+EK+ Sbjct: 61 GMMLTQTRAILSYLAAKYNLYGKDLKERVRIDMYADGTQDLMMMIAVAPFKTPKEKEESY 120 Query: 122 ALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLISNFPLL 181 LI + K+RYFP FEK+L+ HG+ +LVGN+LS ADI L+E + VEEL + ++S+FPLL Sbjct: 121 DLILSRAKTRYFPVFEKILKDHGEAFLVGNQLSWADIQLLEAILMVEELSAPVLSDFPLL 180 Query: 182 KALKTRISNLPTVKKFLQPGSPRKPPADAKALEEARKIFRF 222 +A KTRISN+PT+KKFLQPGS RKPP D +E R + +F Sbjct: 181 QAFKTRISNIPTIKKFLQPGSQRKPPPDGPYVEVVRIVLKF 221 >1VF1-A nrPDB Length = 229 Score = 275 bits (704), Expect = 9e-75, Method: Composition-based stats. Identities = 142/222 (63%), Positives = 166/222 (74%) Query: 1 MAGKPKLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQVPMVEI 60 MA KP L+YFNGRG+ME IRWLLAAAGVEFEE F+ + E KL G LMFQQVPMVEI Sbjct: 1 MAAKPVLYYFNGRGKMESIRWLLAAAGVEFEEVFLETREQYEKLLQSGILMFQQVPMVEI 60 Query: 61 DGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAK 120 DGMKLVQTRAILNYIA KYNLYGKD+KERALIDMY G DL +L P E+K + Sbjct: 61 DGMKLVQTRAILNYIAGKYNLYGKDLKERALIDMYVGGTDDLMGFLLSFPFLSAEDKVKQ 120 Query: 121 IALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLISNFPL 180 A + EK SRYFPA+EKVL+ HGQD+LVGN+LS ADI L+E + VEE S +S FPL Sbjct: 121 CAFVVEKATSRYFPAYEKVLKDHGQDFLVGNRLSWADIHLLEAILMVEEKKSDALSGFPL 180 Query: 181 LKALKTRISNLPTVKKFLQPGSPRKPPADAKALEEARKIFRF 222 L+A K RIS++PT+KKFL PGS RKP +D K +E R++ R Sbjct: 181 LQAFKKRISSIPTIKKFLAPGSKRKPISDDKYVETVRRVLRM 222 >1EV4-A nrPDB Length = 221 Score = 275 bits (704), Expect = 1e-74, Method: Composition-based stats. Identities = 164/221 (74%), Positives = 194/221 (87%) Query: 2 AGKPKLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQVPMVEID 61 +GKP LHYFN RGRME IR+LLAAAGVEF+EKFI S EDL KL+ DG+LMF QVPMVEID Sbjct: 1 SGKPVLHYFNARGRMECIRFLLAAAGVEFDEKFIQSPEDLEKLKKDGNLMFDQVPMVEID 60 Query: 62 GMKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAKI 121 GMKL QTRAILNYIA+KY+LYGKD+KERALIDMY+EG+ DL EMI+ L +C P++K+AK Sbjct: 61 GMKLAQTRAILNYIATKYDLYGKDMKERALIDMYSEGILDLTEMIMQLVICPPDQKEAKT 120 Query: 122 ALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLISNFPLL 181 AL K++TK+RY PAFEKVL+SHGQDYLVGNKL+R DI L+ELL YVEE D+SL+++FPLL Sbjct: 121 ALAKDRTKNRYLPAFEKVLKSHGQDYLVGNKLTRVDIHLLELLLYVEEFDASLLTSFPLL 180 Query: 182 KALKTRISNLPTVKKFLQPGSPRKPPADAKALEEARKIFRF 222 KA K+RIS+LP VKKFLQPGS RK P DAK +EEARKI++F Sbjct: 181 KAFKSRISSLPNVKKFLQPGSQRKLPMDAKQIEEARKIYKF 221 >1GUL-A nrPDB Length = 222 Score = 257 bits (656), Expect = 4e-69, Method: Composition-based stats. Identities = 118/221 (53%), Positives = 167/221 (75%) Query: 1 MAGKPKLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQVPMVEI 60 MA +PKLHY NGRGRME +RW+LAAAGVEF+E+F+ + E L KL++ L+FQQVPMVEI Sbjct: 1 MAARPKLHYPNGRGRMESVRWVLAAAGVEFDEEFLETKEQLYKLQDGNHLLFQQVPMVEI 60 Query: 61 DGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAK 120 DGMKLVQTR+IL+YIA K+NL+GK++KER LIDMY EG DL E++++ P +P+++ + Sbjct: 61 DGMKLVQTRSILHYIADKHNLFGKNLKERTLIDMYVEGTLDLLELLIMHPFLKPDDQQKE 120 Query: 121 IALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLISNFPL 180 + + +K RYFP FEK+L+ HGQ +LVGN+LS AD+ L++ + +EE +++S FP Sbjct: 121 VVNMAQKAIIRYFPVFEKILRGHGQSFLVGNQLSLADVILLQTILALEEKIPNILSAFPF 180 Query: 181 LKALKTRISNLPTVKKFLQPGSPRKPPADAKALEEARKIFR 221 L+ ++SN+PT+K+FL+PGS +KPP D + IFR Sbjct: 181 LQEYTVKLSNIPTIKRFLEPGSKKKPPPDEIYVRTVYNIFR 221 >3GTU-B nrPDB Length = 224 Score = 234 bits (597), Expect = 2e-62, Method: Composition-based stats. Identities = 55/220 (25%), Positives = 88/220 (40%), Gaps = 12/220 (5%) Query: 6 KLHYFNGRGRMEPIRWLLAAAGVEFEEKFI--GSAEDLGK-----LRNDGSLMFQQVPMV 58 L Y++ RG IR LL +EEK G A D + ++ L F +P + Sbjct: 7 VLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLPYL 66 Query: 59 EIDGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKD 118 K+ Q+ AIL YIA K+N+ G+ +E+ +D+ + D + + LC + + Sbjct: 67 LDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQL--IRLCYSSDHE 124 Query: 119 AKIALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLISNF 178 K+ + F L + G KL+ D ++L D + F Sbjct: 125 -KLKPQYLEELPGQLKQFSMFLGKFS--WFAGEKLTFVDFLTYDILDQNRIFDPKCLDEF 181 Query: 179 PLLKALKTRISNLPTVKKFLQPGSPRKPPADAKALEEARK 218 P LKA R L + +LQ K P + K + K Sbjct: 182 PNLKAFMCRFEALEKIAAYLQSDQFCKMPINNKMAQWGNK 221 >1XWK-A nrPDB Length = 218 Score = 227 bits (579), Expect = 3e-60, Method: Composition-based stats. Identities = 54/220 (24%), Positives = 91/220 (41%), Gaps = 12/220 (5%) Query: 6 KLHYFNGRGRMEPIRWLLAAAGVEFEEK--FIGSAEDLGKL-----RNDGSLMFQQVPMV 58 L Y++ RG IR LL +EEK +G A D + + L F +P + Sbjct: 4 ILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYL 63 Query: 59 EIDGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKD 118 K+ Q+ AIL YIA K+NL G+ +E+ +D+ D N M L + PE + Sbjct: 64 IDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMD-NHMQLGMICYNPEFEK 122 Query: 119 AKIALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLISNF 178 K ++E + + L + + GNK++ D + ++L + + F Sbjct: 123 LKPKYLEE--LPEKLKLYSEFLGK--RPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAF 178 Query: 179 PLLKALKTRISNLPTVKKFLQPGSPRKPPADAKALEEARK 218 P LK +R L + +++ P +K K Sbjct: 179 PNLKDFISRFEGLEKISAYMKSSRFLPRPVFSKMAVWGNK 218 >5FWG-A nrPDB Length = 217 Score = 226 bits (576), Expect = 8e-60, Method: Composition-based stats. Identities = 53/220 (24%), Positives = 93/220 (42%), Gaps = 12/220 (5%) Query: 6 KLHYFNGRGRMEPIRWLLAAAGVEFEEKF--IGSAEDLGKL-----RNDGSLMFQQVPMV 58 L Y+N RG PIR LL +EEK +G A D + + L F +P + Sbjct: 3 ILGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLPYL 62 Query: 59 EIDGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKD 118 K+ Q+ AI+ Y+A K++L G+ +ER D+ + D N M L++ P+ + Sbjct: 63 IDGSRKITQSNAIMRYLARKHHLCGETEEERIRADIVENQVMD-NRMQLIMLCYNPDFEK 121 Query: 119 AKIALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLISNF 178 K + KT + + L + + G+K++ D ++L + + F Sbjct: 122 QKPEFL--KTIPEKMKLYSEFLGK--RPWFAGDKVTYVDFLAYDILDQYHIFEPKCLDAF 177 Query: 179 PLLKALKTRISNLPTVKKFLQPGSPRKPPADAKALEEARK 218 P LK R L + +++ P +K + + K Sbjct: 178 PNLKDFLARFEGLKKISAYMKSSRYLSTPIFSKLAQWSNK 217 >4GTU-A nrPDB Length = 217 Score = 223 bits (570), Expect = 4e-59, Method: Composition-based stats. Identities = 50/220 (22%), Positives = 91/220 (41%), Gaps = 12/220 (5%) Query: 6 KLHYFNGRGRMEPIRWLLAAAGVEFEEK--FIGSAEDLGKL-----RNDGSLMFQQVPMV 58 L Y++ RG IR LL +EEK +G A D + + L F +P + Sbjct: 3 TLGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYL 62 Query: 59 EIDGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKD 118 K+ Q+ AIL YIA K+NL G+ +E+ +D+ D++ + + P+ + Sbjct: 63 IDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQAMDVSNQLARV-CYSPDFEK 121 Query: 119 AKIALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLISNF 178 K ++E F + L + + VG+K++ D ++L + + + F Sbjct: 122 LKPEYLEE--LPTMMQHFSQFLGK--RPWFVGDKITFVDFLAYDVLDLHRIFEPNCLDAF 177 Query: 179 PLLKALKTRISNLPTVKKFLQPGSPRKPPADAKALEEARK 218 P LK +R L + +++ P + K Sbjct: 178 PNLKDFISRFEGLEKISAYMKSSRFLPKPLYTRVAVWGNK 217 >1B4P-A nrPDB Length = 217 Score = 223 bits (569), Expect = 4e-59, Method: Composition-based stats. Identities = 52/220 (23%), Positives = 90/220 (40%), Gaps = 12/220 (5%) Query: 6 KLHYFNGRGRMEPIRWLLAAAGVEFEEKF--IGSAEDLGKL-----RNDGSLMFQQVPMV 58 L Y+N RG PIR LL +EEK +G A D + + L F +P + Sbjct: 3 ILGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLPYL 62 Query: 59 EIDGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKD 118 K+ Q+ AI+ Y+A K++L G+ +ER +D+ D + ++ P+ + Sbjct: 63 IDGSRKITQSNAIMRYLARKHHLCGETEEERIRVDVLENQAMDTRLQLAMV-CYSPDFER 121 Query: 119 AKIALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLISNF 178 K + + + + L Q + GNK++ D + ++L + + F Sbjct: 122 KKPEYL--EGLPEKMKLYSEFLGK--QPWFAGNKITYVDFLVYDVLDQHRIFEPKCLDAF 177 Query: 179 PLLKALKTRISNLPTVKKFLQPGSPRKPPADAKALEEARK 218 P LK R L + +++ G P AK K Sbjct: 178 PNLKDFVARFEGLKKISDYMKSGRFLSKPIFAKMAFWNPK 217 >2DC5-A nrPDB Length = 231 Score = 221 bits (564), Expect = 2e-58, Method: Composition-based stats. Identities = 51/230 (22%), Positives = 91/230 (39%), Gaps = 23/230 (10%) Query: 2 AGKP-KLHYFNGRGRMEPIRWLLAAAGVEFEEKF--IGSAEDLGKL-----RNDGSLMFQ 53 +G P L Y++ RG IR L +EEK +G A D + + L F Sbjct: 6 SGMPMTLGYWDIRGLAHAIRLFLEYTDSSYEEKRYTMGDAPDYDQSQWLNEKFKLGLDFP 65 Query: 54 QVPMVEIDGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCR 113 +P + K+ Q+ AIL Y+ K+NL G+ +ER +D+ + D ++L LC Sbjct: 66 NLPYLIDGSHKITQSNAILRYLGRKHNLCGETEEERIRVDILENQLMD--NRMVLARLCY 123 Query: 114 PEEKDAKIALIKEKTKSRYFPAFEKVLQSHG-----QDYLVGNKLSRADISLVELLYYVE 168 + EK K Y +++ + + + G+K++ D ++L + Sbjct: 124 NAD--------FEKLKPGYLEQLPGMMRLYSEFLGKRPWFAGDKITFVDFIAYDVLERNQ 175 Query: 169 ELDSSLISNFPLLKALKTRISNLPTVKKFLQPGSPRKPPADAKALEEARK 218 ++ + FP LK R L + +++ P K Sbjct: 176 VFEAKCLDAFPNLKDFIARFEGLKKISDYMKTSRFLPRPMFTKMATWGSN 225 >5D73-A nrPDB Length = 208 Score = 220 bits (560), Expect = 4e-58, Method: Composition-based stats. Identities = 67/214 (31%), Positives = 109/214 (50%), Gaps = 10/214 (4%) Query: 4 KPKLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQVPMVEIDGM 63 KL YF RG EPIR +L G++F + I A D +++ F Q+P + Sbjct: 2 SYKLTYFPIRGLAEPIRLVLVDQGIKFTDDRIN-ASDWPSMKS--HFHFGQLPCLYDGDH 58 Query: 64 KLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLN-EMILLLPLCRPEEKDAKIA 122 ++VQ+ AIL ++A K+NL G + E IDM+ EG+ DL+ + ++ EKD+ I Sbjct: 59 QIVQSGAILRHLARKHNLNGGNELETTHIDMFCEGVRDLHTKYTKMIYQAYDTEKDSYIK 118 Query: 123 LIKEKTKSRYFPAFEKVLQSH--GQDYLVGNKLSRADISLVELLYYVEELDSSLISNFPL 180 I FEK+L + G+++++G K+S D L E L + LD + FPL Sbjct: 119 DI----LPVELAKFEKLLATRDDGKNFILGEKISYVDFVLFEELDIHQILDPHCLDKFPL 174 Query: 181 LKALKTRISNLPTVKKFLQPGSPRKPPADAKALE 214 LKA R+ + P +K++ + + K P + + Sbjct: 175 LKAYHQRMEDRPGLKEYCKQRNRAKIPVNGNGKQ 208 >2GSR-A nrPDB Length = 207 Score = 218 bits (557), Expect = 1e-57, Method: Composition-based stats. Identities = 67/214 (31%), Positives = 105/214 (49%), Gaps = 9/214 (4%) Query: 3 GKPKLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQVPMVEIDG 62 + YF RGR E +R LLA ++E+ + + E L+ S +F+Q+P + Sbjct: 1 PPYTITYFPVRGRCEAMRMLLADQDQSWKEEVV-TMETWPPLKP--SCLFRQLPKFQDGD 57 Query: 63 MKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAKIA 122 + L Q+ AIL ++ + LYGKD KE AL+DM +G+ DL L E K Sbjct: 58 LTLYQSNAILRHLGRSFGLYGKDQKEAALVDMVNDGVEDLRCKYATLIYTNYEAGKEK-- 115 Query: 123 LIKEKTKSRYFPAFEKVLQSH--GQDYLVGNKLSRADISLVELLYYVEELDSSLISNFPL 180 K + FE +L + GQ ++VG+++S AD +L++LL + L+ S + FPL Sbjct: 116 --YVKELPEHLKPFETLLSQNQGGQAFVVGSQISFADYNLLDLLRIHQVLNPSCLDAFPL 173 Query: 181 LKALKTRISNLPTVKKFLQPGSPRKPPADAKALE 214 L A R+S P +K FL P + + Sbjct: 174 LSAYVARLSARPKIKAFLASPEHVNRPINGNGKQ 207 >2FHE-A nrPDB Length = 216 Score = 215 bits (549), Expect = 8e-57, Method: Composition-based stats. Identities = 58/214 (27%), Positives = 97/214 (45%), Gaps = 9/214 (4%) Query: 6 KLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKL---RNDGSLMFQQVPMVEIDG 62 KL Y+ RG +P+R LL G ++EE+ I +D K + + L +P D Sbjct: 3 KLGYWKIRGLQQPVRLLLEYLGEKYEEQ-IYERDDGEKWFSKKFELGLDLPNLPYYIDDK 61 Query: 63 MKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAKIA 122 KL Q+ AIL YIA K+ + G +ERA + M DL + I + +P+ + K Sbjct: 62 CKLTQSLAILRYIADKHGMIGTTSEERARVSMIEGAAVDLRQGISRISY-QPKFEQLKEG 120 Query: 123 LIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLISNFPLLK 182 +K+ + L + YL G +S D + E L + L+ + +FP L+ Sbjct: 121 YLKD--LPTTMKMWSDFLGKN--PYLRGTSVSHVDFMVYEALDAIRYLEPHCLDHFPNLQ 176 Query: 183 ALKTRISNLPTVKKFLQPGSPRKPPADAKALEEA 216 +RI LP++K +++ K P + + Sbjct: 177 QFMSRIEALPSIKAYMESNRFIKWPLNGWHAQFG 210 >2GLR-A nrPDB Length = 209 Score = 214 bits (546), Expect = 2e-56, Method: Composition-based stats. Identities = 60/214 (28%), Positives = 101/214 (47%), Gaps = 7/214 (3%) Query: 3 GKPKLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQVPMVEIDG 62 + YF RGR E +R LLA G ++E+ + + + + + ++ Q+P E Sbjct: 1 PPYTIVYFPVRGRCEAMRMLLADQGQSWKEEVV-TIDTWMQGLLKPTCLYGQLPKFEDGD 59 Query: 63 MKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAKIA 122 + L Q+ AIL ++ LYGK+ +E A +DM +G+ DL + L E Sbjct: 60 LTLYQSNAILRHLGRSLGLYGKNQREAAQMDMVNDGVEDLRGKYVTLIYTNYENGKND-- 117 Query: 123 LIKEKTKSRYFPAFEKVLQSH--GQDYLVGNKLSRADISLVELLYYVEELDSSLISNFPL 180 K + FE +L + G+ ++VG+++S AD +L++LL + L + NFPL Sbjct: 118 --YVKALPGHLKPFETLLSQNQGGKAFIVGDQISFADYNLLDLLLIHQVLAPGCLDNFPL 175 Query: 181 LKALKTRISNLPTVKKFLQPGSPRKPPADAKALE 214 L A R+S P +K FL P + + Sbjct: 176 LSAYVARLSARPKIKAFLSSPEHVNRPINGNGKQ 209 >1HNA-A nrPDB Length = 217 Score = 214 bits (546), Expect = 2e-56, Method: Composition-based stats. Identities = 58/225 (25%), Positives = 92/225 (40%), Gaps = 22/225 (9%) Query: 6 KLHYFNGRGRMEPIRWLLAAAGVEFEEK--FIGSAEDLGKL-----RNDGSLMFQQVPMV 58 L Y+N RG IR LL +EEK +G A D + + L F +P + Sbjct: 3 TLGYWNIRGLAHSIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYL 62 Query: 59 EIDGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKD 118 K+ Q+ AIL YIA K+NL G+ KE+ D+ D + L LC + Sbjct: 63 IDGTHKITQSNAILRYIARKHNLCGESEKEQIREDILENQFMDSR--MQLAKLCYDPD-- 118 Query: 119 AKIALIKEKTKSRYFPAFEKVLQSHG-----QDYLVGNKLSRADISLVELLYYVEELDSS 173 EK K Y A ++L+ + Q + +G+K++ D ++L + + S Sbjct: 119 ------FEKLKPEYLQALPEMLKLYSQFLGKQPWFLGDKITFVDFIAYDVLERNQVFEPS 172 Query: 174 LISNFPLLKALKTRISNLPTVKKFLQPGSPRKPPADAKALEEARK 218 + FP LK +R L + +++ P K K Sbjct: 173 CLDAFPNLKDFISRFEGLEKISAYMKSSRFLPRPVFTKMAVFGNK 217 >5AN1-A nrPDB Length = 219 Score = 214 bits (545), Expect = 3e-56, Method: Composition-based stats. Identities = 60/217 (27%), Positives = 97/217 (44%), Gaps = 14/217 (6%) Query: 5 PKLHYFNGRGRMEPIRWLLAAAGVEFEEK--FIGSAEDLGK-----LRNDGSLMFQQVPM 57 P L Y+ R +PIR +L G EFEEK +G A D K ++ L F +P Sbjct: 3 PVLGYWKTRALCQPIRLMLGYTGTEFEEKNYPVGDAPDYDKSEWLAVKFKLGLAFPNLPY 62 Query: 58 VEIDGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEK 117 +K+ Q++AI+ Y+A K+ L G +E DM + D++E + E+K Sbjct: 63 YIDGDVKITQSKAIMRYLARKHGLCGTTPEELVRTDMIECQLTDMHEAFFTVTYEHYEQK 122 Query: 118 DAKIALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLISN 177 DA A + K + + L S + + G+KL+ D E+ LD + + Sbjct: 123 DAYTASLPAKLR-----QYSDFLGS--RPWFAGDKLTYIDFLAYEIFDQHLSLDRTCLDG 175 Query: 178 FPLLKALKTRISNLPTVKKFLQPGSPRKPPADAKALE 214 F L+A + R +L +KK++ K P K + Sbjct: 176 FKNLQAFQKRFEDLEAIKKYMASPKFLKKPICNKYAQ 212 >1GSU-A nrPDB Length = 219 Score = 207 bits (526), Expect = 4e-54, Method: Composition-based stats. Identities = 48/220 (21%), Positives = 82/220 (37%), Gaps = 12/220 (5%) Query: 6 KLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAE-------DLGKLRNDGSLMFQQVPMV 58 L Y++ RG IR LL ++E+ + D + L F +P + Sbjct: 3 TLGYWDIRGLAHAIRLLLEYTETPYQERRYKAGPAPDFDPSDWTNEKEKLGLDFPNLPYL 62 Query: 59 EIDGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKD 118 +KL Q+ AIL YIA K+N+ G+ E+ +D+ + DL L P+ + Sbjct: 63 IDGDVKLTQSNAILRYIARKHNMCGETEVEKQRVDVLENHLMDLRMAFARL-CYSPDFEK 121 Query: 119 AKIALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLISNF 178 K A +++ + L S + + VG+KL+ D ++L Sbjct: 122 LKPAYLEQ--LPGKLRQLSRFLGS--RSWFVGDKLTFVDFLAYDVLDQQRMFVPDCPELQ 177 Query: 179 PLLKALKTRISNLPTVKKFLQPGSPRKPPADAKALEEARK 218 L R L + +++ G K P K Sbjct: 178 GNLSQFLQRFEALEKISAYMRSGRFMKAPIFWYTALWNNK 217 >18GS-A nrPDB Length = 210 Score = 206 bits (525), Expect = 6e-54, Method: Composition-based stats. Identities = 61/214 (28%), Positives = 98/214 (45%), Gaps = 7/214 (3%) Query: 3 GKPKLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQVPMVEIDG 62 + YF RGR +R LLA G ++E+ + + E + S ++ Q+P + Sbjct: 2 PPYTVVYFPVRGRCAALRMLLADQGQSWKEEVV-TVETWQEGSLKASCLYGQLPKFQDGD 60 Query: 63 MKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAKIA 122 + L Q+ IL ++ LYGKD +E AL+DM +G+ DL + L E Sbjct: 61 LTLYQSNTILRHLGRTLGLYGKDQQEAALVDMVNDGVEDLRCKYISLIYTNYEAGK---- 116 Query: 123 LIKEKTKSRYFPAFEKVLQSH--GQDYLVGNKLSRADISLVELLYYVEELDSSLISNFPL 180 K FE +L + G+ ++VG+++S AD +L++LL E L + FPL Sbjct: 117 DDYVKALPGQLKPFETLLSQNQGGKTFIVGDQISFADYNLLDLLLIHEVLAPGCLDAFPL 176 Query: 181 LKALKTRISNLPTVKKFLQPGSPRKPPADAKALE 214 L A R+S P +K FL P + + Sbjct: 177 LSAYVGRLSARPKLKAFLASPEYVNLPINGNGKQ 210 >4Q5F-A nrPDB Length = 218 Score = 205 bits (523), Expect = 9e-54, Method: Composition-based stats. Identities = 59/207 (28%), Positives = 98/207 (47%), Gaps = 9/207 (4%) Query: 3 GKPKLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQVPMVEIDG 62 + KL YF+ RG E R + AGV+FE+ + ED L+ F Q+P++E+DG Sbjct: 14 PQYKLTYFDIRGLGEGARLIFHQAGVKFEDNRLK-REDWPALKPK--TPFGQLPLLEVDG 70 Query: 63 MKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMAD----LNEMILLLPLCRPEEKD 118 L Q+ AI Y+ ++ L GK E A +D + D L +L +K+ Sbjct: 71 EVLAQSAAIYRYLGRQFGLAGKTPMEEAQVDSIFDQFKDFMAELRPCFRVLAGFEEGDKE 130 Query: 119 AKIALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLISNF 178 + + + ++ P EK L G +Y+VG ++ AD+ + + L E L +S Sbjct: 131 KVLKEVAVPARDKHLPLLEKFLAKSGSEYMVGKSVTWADLVITDSLASWESLIPDFLSGH 190 Query: 179 PLLKALKTRISNLPTVKKFL--QPGSP 203 LK + LP +KK++ +P +P Sbjct: 191 LQLKKYIEHVRELPNIKKWIAERPKTP 217 >1TU7-A nrPDB Length = 208 Score = 204 bits (520), Expect = 2e-53, Method: Composition-based stats. Identities = 66/214 (30%), Positives = 111/214 (51%), Gaps = 10/214 (4%) Query: 4 KPKLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQVPMVEIDGM 63 KL YF+ RG EPIR L ++F + I + +D +++ F Q+P + Sbjct: 2 SYKLTYFSIRGLAEPIRLFLVDQDIKFIDDRI-AKDDFSSIKSQFQ--FGQLPCLYDGDQ 58 Query: 64 KLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLN-EMILLLPLCRPEEKDAKIA 122 ++VQ+ AIL ++A KYNL G++ E IDM+ EG+ DL+ + ++ + EKD I Sbjct: 59 QIVQSGAILRHLARKYNLNGENEMETTYIDMFCEGVRDLHVKYTRMIYMAYETEKDPYIK 118 Query: 123 LIKEKTKSRYFPAFEKVLQS--HGQDYLVGNKLSRADISLVELLYYVEELDSSLISNFPL 180 I FEK+L + +G++ ++G+K+S AD +L E L + LD + FPL Sbjct: 119 SI----LPGELAKFEKLLATRGNGRNLILGDKISYADYALFEELDVHQILDPHCLDKFPL 174 Query: 181 LKALKTRISNLPTVKKFLQPGSPRKPPADAKALE 214 LK R+ + P +K++ + K P + + Sbjct: 175 LKVFHQRMKDRPKLKEYCEKRDAAKVPVNGNGKQ 208 >4Q5R-A nrPDB Length = 204 Score = 203 bits (516), Expect = 6e-53, Method: Composition-based stats. Identities = 67/211 (31%), Positives = 108/211 (51%), Gaps = 10/211 (4%) Query: 1 MAGKPKLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQVPMVEI 60 MA KL Y + EPIR+LL+ +FE+ D L+ S+ F + P++EI Sbjct: 1 MAPSYKLTYCPVKALGEPIRFLLSYGEKDFEDYRFQE-GDWPNLKP--SMPFGKTPVLEI 57 Query: 61 DGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEE-KDA 119 DG + Q+ AI Y+ ++ L GKD E IDM + ++D I E K Sbjct: 58 DGKQTHQSVAISRYLGKQFGLSGKDDWENLEIDMIVDTISDFRAAIANYHYDADENSKQK 117 Query: 120 KIALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEEL-DSSLISNF 178 K +K++T Y F++V++++G YL KL+ AD V +L Y+ + L++N Sbjct: 118 KWDPLKKETIPYYTKKFDEVVKANGG-YLAAGKLTWADFYFVAILDYLNHMAKEDLVANQ 176 Query: 179 PLLKALKTRISNLPTVKKFLQPGSPRKPPAD 209 P LKAL+ ++ LP +K ++ ++PP D Sbjct: 177 PNLKALREKVLGLPAIKAWVA----KRPPTD 203 >3KXO-A nrPDB Length = 202 Score = 201 bits (511), Expect = 2e-52, Method: Composition-based stats. Identities = 50/205 (24%), Positives = 96/205 (46%), Gaps = 10/205 (4%) Query: 3 GKPKLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQVPMVEIDG 62 KL YFN RGR E IR++ A +++E+ I A D ++++ +L F ++P++E+DG Sbjct: 5 PNYKLTYFNMRGRAEIIRYIFAYLDIQYEDHRIEQA-DWPEIKS--TLPFGKIPILEVDG 61 Query: 63 MKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAKIA 122 + L Q+ AI Y+ +L G E+ +D + + D E+K Sbjct: 62 LTLHQSLAIARYLTKNTDLAGNTEMEQCHVDAIVDTLDDFMSCF-----PWAEKKQDVKE 116 Query: 123 LIKEKTKSRYFPAFEKVLQSH--GQDYLVGNKLSRADISLVELLYYVEELDSSLISNFPL 180 + + + P + L ++ G+++L+GN ++ AD + L+ N P Sbjct: 117 QMFNELLTYNAPHLMQDLDTYLGGREWLIGNSVTWADFYWEICSTTLLVFKPDLLDNHPR 176 Query: 181 LKALKTRISNLPTVKKFLQPGSPRK 205 L L+ ++ +P V +++ K Sbjct: 177 LVTLRKKVQAIPAVANWIKRRPQTK 201 >1FHE-A nrPDB Length = 217 Score = 197 bits (502), Expect = 3e-51, Method: Composition-based stats. Identities = 59/213 (27%), Positives = 87/213 (40%), Gaps = 7/213 (3%) Query: 6 KLHYFNGRGRMEPIRWLLAAAGVEFEEKFIG--SAEDLGKLRNDGSLMFQQVPMVEIDGM 63 KL Y+ RG +P+R L G E+EE G E + + L +P D Sbjct: 3 KLGYWKLRGLAQPVRLFLEYLGEEYEEHLYGRDDREKWMSEKFNMGLDLPNLPYYIDDKC 62 Query: 64 KLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAKIAL 123 KL Q+ AI+ YIA K+ + G +ERA I M DL + K ++ Sbjct: 63 KLTQSVAIMRYIADKHGMLGTTPEERARISMIEGAAMDLRIGFGRVCY---NPKFEEVKE 119 Query: 124 IKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLISNFPLLKA 183 K + + L + YL G+ +S D L E L + L + FP LK Sbjct: 120 EYVKELPKTLKMWSDFLGD--RHYLTGSSVSHVDFMLYETLDSIRYLAPHCLDEFPKLKE 177 Query: 184 LKTRISNLPTVKKFLQPGSPRKPPADAKALEEA 216 K+RI LP +K +++ K P + A Sbjct: 178 FKSRIEALPKIKAYMESKRFIKWPLNGWAASFG 210 >4Q5Q-A nrPDB Length = 219 Score = 197 bits (502), Expect = 3e-51, Method: Composition-based stats. Identities = 59/209 (28%), Positives = 95/209 (45%), Gaps = 12/209 (5%) Query: 3 GKPKLHYFNGRGRMEPIRWLLAAAGVEFEEKF--IGSAEDLGKL-----RNDGSLMFQQV 55 +P L Y++ RG +PIR LL +GV+F +K IG A D + + + L F + Sbjct: 2 SQPILGYWDIRGYAQPIRLLLTYSGVDFVDKRYQIGPAPDFDRSEWLNEKFNLGLDFPNL 61 Query: 56 PMVEIDGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPE 115 P MK+ QT AIL Y+ KY L G + E I M + D+ M ++ +C Sbjct: 62 PYYIDGDMKMTQTFAILRYLGRKYKLNGSNDHEEIRISMAEQQTEDM--MAAMIRVCYDA 119 Query: 116 EKDAKIALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLI 175 D K+ K+ K + H ++ G +S D +L E L +V+ + + Sbjct: 120 NCD-KLKPDYLKSLPDCLKLMSKFVGEHA--FIAGANISYVDFNLYEYLCHVKVMVPEVF 176 Query: 176 SNFPLLKALKTRISNLPTVKKFLQPGSPR 204 F LK R+ +LP V +++ P+ Sbjct: 177 GQFENLKRYVERMESLPRVSDYIKKQQPK 205 >2AAW-A nrPDB Length = 222 Score = 197 bits (501), Expect = 4e-51, Method: Composition-based stats. Identities = 62/208 (29%), Positives = 103/208 (49%), Gaps = 15/208 (7%) Query: 1 MAGKPKLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAED----LGKLRNDGSLMFQQVP 56 M L+YF+ RG+ E IR + A G+E+ +K G D + + F+QVP Sbjct: 12 MGDNIVLYYFDARGKAELIRLIFAYLGIEYTDKRFGVNGDAFVEFKNFKKEKDTPFEQVP 71 Query: 57 MVEIDGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEE 116 +++I + L Q++AI+ Y++ KYN+ G+ DM G+ D++ L + E Sbjct: 72 ILQIGDLILAQSQAIVRYLSKKYNICGESELNEFYADMIFCGVQDIHYKFNNTNLFKQNE 131 Query: 117 KDAKIALIKEKTKSRYFPAFEKVLQSHGQD------YLVGNKLSRADISLVELLYYVEEL 170 + ++ FEK+L+ + + Y VGN L+ AD+++ L +E Sbjct: 132 -----TTFLNEDLPKWSGYFEKLLKKNHTNNNNDKYYFVGNNLTYADLAVFNLYDDIETK 186 Query: 171 DSSLISNFPLLKALKTRISNLPTVKKFL 198 S + NFPLLKA ISNLP +K ++ Sbjct: 187 YPSSLKNFPLLKAHNEFISNLPNIKNYI 214 >1GSQ-A nrPDB Length = 202 Score = 196 bits (498), Expect = 8e-51, Method: Composition-based stats. Identities = 58/204 (28%), Positives = 101/204 (49%), Gaps = 6/204 (2%) Query: 3 GKPKLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQVPMVEIDG 62 K LHYF GR E R++LAA G EF ++ + A D L+ ++ +P+++IDG Sbjct: 1 PKYTLHYFPLMGRAELCRFVLAAHGEEFTDRVVEMA-DWPNLK--ATMYSNAMPVLDIDG 57 Query: 63 MKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAKIA 122 K+ Q+ I ++A ++ L GK E+ +D TE + D+ ++ + PE + Sbjct: 58 TKMSQSMCIARHLAREFGLDGKTSLEKYRVDEITETLQDIFNDVVKIK-FAPEAAKEAVQ 116 Query: 123 LIKEKTKSRYFPAFEKVLQSHGQ--DYLVGNKLSRADISLVELLYYVEELDSSLISNFPL 180 EK+ R P E +L S+G + VGN ++ AD+ L + L+ + P Sbjct: 117 QNYEKSCKRLAPFLEGLLVSNGGGDGFFVGNSMTLADLHCYVALEVPLKHTPELLKDCPK 176 Query: 181 LKALKTRISNLPTVKKFLQPGSPR 204 + AL+ R++ P + +L+ R Sbjct: 177 IVALRKRVAECPKIAAYLKKRPVR 200 >1ZL9-A nrPDB Length = 207 Score = 194 bits (494), Expect = 2e-50, Method: Composition-based stats. Identities = 54/202 (26%), Positives = 96/202 (47%), Gaps = 6/202 (2%) Query: 4 KPKLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQVPMVEIDGM 63 KL YFNGRG E R + A AG ++E+ + + E L+ + F Q+P +E+DG Sbjct: 3 SYKLTYFNGRGAGEVSRQIFAYAGQQYEDNRV-TQEQWPALKETCAAPFGQLPFLEVDGK 61 Query: 64 KLVQTRAILNYIASKYNLYGKDIKERALI----DMYTEGMADLNEMILLLPLCRPEEKDA 119 KL Q+ AI ++A ++ L GK E A + D Y + ++ + P + + Sbjct: 62 KLAQSHAIARFLAREFKLNGKTAWEEAQVNSLADQYKDYSSEARPYFYAVMGFGPGDVET 121 Query: 120 KIALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLISNFP 179 I +++ L++ G +LVG+ L+ D+++ + + S FP Sbjct: 122 LKKDIFLPAFEKFYGFLVNFLKASGSGFLVGDSLTWIDLAIAQHSADL-IAKGGDFSKFP 180 Query: 180 LLKALKTRISNLPTVKKFLQPG 201 LKA +I +P +KK+++ Sbjct: 181 ELKAHAEKIQAIPQIKKWIETR 202 >2WRT-A nrPDB Length = 218 Score = 194 bits (493), Expect = 3e-50, Method: Composition-based stats. Identities = 58/214 (27%), Positives = 94/214 (43%), Gaps = 21/214 (9%) Query: 6 KLHYFNGRGRMEPIRWLL---------AAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQVP 56 KL Y+ RG +P+R LL G + EK++G + + L +P Sbjct: 4 KLGYWKIRGLQQPVRLLLEYLGEEYEEHLYGRDDREKWLGD-------KFNMGLDLPNLP 56 Query: 57 MVEIDGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEE 116 D KL Q+ AI+ YIA K+ + G +ERA I M DL + + P+ Sbjct: 57 YYIDDKCKLTQSVAIMRYIADKHGMLGSTPEERARISMIEGAAMDLRMGFVRV-CYNPKF 115 Query: 117 KDAKIALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLIS 176 ++ K +KE + L + YL G+ +S D + E L + L + Sbjct: 116 EEVKGDYLKE--LPTTLKMWSNFLGD--RHYLTGSSVSHVDFMVYEALDCIRYLAPQCLE 171 Query: 177 NFPLLKALKTRISNLPTVKKFLQPGSPRKPPADA 210 +FP LK K+RI +LP +K +++ K P ++ Sbjct: 172 DFPKLKEFKSRIEDLPKIKAYMESEKFIKWPLNS 205 >1B8X-A nrPDB Length = 280 Score = 192 bits (489), Expect = 8e-50, Method: Composition-based stats. Identities = 53/212 (25%), Positives = 86/212 (40%), Gaps = 7/212 (3%) Query: 4 KPKLHYFNGRGRMEPIRWLLAAAGVEFEEKFIG--SAEDLGKLRNDGSLMFQQVPMVEID 61 P L Y+ +G ++P R LL ++EE + + + L F +P Sbjct: 1 SPILGYWKIKGLVQPTRLLLEYLEEKYEEHLYERDEGDKWRNKKFELGLEFPNLPYYIDG 60 Query: 62 GMKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAKI 121 +KL Q+ AI+ YIA K+N+ G KERA I M + D+ + + + E + Sbjct: 61 DVKLTQSMAIIRYIADKHNMLGGCPKERAEISMLEGAVLDIRYGVSRIAYSKDFET---L 117 Query: 122 ALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLISNFPLL 181 + FE L + YL G+ ++ D L + L V +D + FP L Sbjct: 118 KVDFLSKLPEMLKMFEDRL--CHKTYLNGDHVTHPDFMLYDALDVVLYMDPMCLDAFPKL 175 Query: 182 KALKTRISNLPTVKKFLQPGSPRKPPADAKAL 213 K RI +P + K+L+ P Sbjct: 176 VCFKKRIEAIPQIDKYLKSSKYIAWPLQGWQA 207 >5Y9Z-A nrPDB Length = 199 Score = 190 bits (484), Expect = 3e-49, Method: Composition-based stats. Identities = 53/205 (25%), Positives = 99/205 (48%), Gaps = 10/205 (4%) Query: 3 GKPKLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQVPMVEIDG 62 KL YFN RGR E IR++ A +++E+ I A D K++ +L F ++P++E++G Sbjct: 2 PNYKLLYFNMRGRAEIIRYIFAYLDIKYEDHRIEQA-DWPKIKP--TLPFGKIPVLEVEG 58 Query: 63 MKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAKIA 122 + L Q+ AI Y+ +L GK E+ +D + + D + L P E +D K Sbjct: 59 LTLHQSLAIARYLTKNTDLAGKTELEQCQVDAVVDTLDDF---MSLFPW-AEENQDLKER 114 Query: 123 LIKEKTKSRYFPAFEKVLQSH--GQDYLVGNKLSRADISLVELLYYVEELDSSLISNFPL 180 + +R P K L ++ +++ +GN ++ AD + L L+ +P Sbjct: 115 TFND-LLTRQAPHLLKDLDTYLGDKEWFIGNYVTWADFYWDICSTTLLVLKPDLLGIYPR 173 Query: 181 LKALKTRISNLPTVKKFLQPGSPRK 205 L +L+ ++ +P + ++ K Sbjct: 174 LVSLRNKVQAIPAISAWILKRPQTK 198 >1DUG-A nrPDB Length = 234 Score = 190 bits (484), Expect = 3e-49, Method: Composition-based stats. Identities = 53/212 (25%), Positives = 86/212 (40%), Gaps = 7/212 (3%) Query: 4 KPKLHYFNGRGRMEPIRWLLAAAGVEFEEKFIG--SAEDLGKLRNDGSLMFQQVPMVEID 61 P L Y+ +G ++P R LL ++EE + + + L F +P Sbjct: 1 SPILGYWKIKGLVQPTRLLLEYLEEKYEEHLYERDEGDKWRNKKFELGLEFPNLPYYIDG 60 Query: 62 GMKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAKI 121 +KL Q+ AI+ YIA K+N+ G KERA I M + D+ + + + E + Sbjct: 61 DVKLTQSMAIIRYIADKHNMLGGCPKERAEISMLEGAVLDIRYGVSRIAYSKDFET---L 117 Query: 122 ALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLISNFPLL 181 + FE L + YL G+ ++ D L + L V +D + FP L Sbjct: 118 KVDFLSKLPEMLKMFEDRL--CHKTYLNGDHVTHPDFMLYDALDVVLYMDPMCLDAFPKL 175 Query: 182 KALKTRISNLPTVKKFLQPGSPRKPPADAKAL 213 K RI +P + K+L+ P Sbjct: 176 VCFKKRIEAIPQIDKYLKSSKYIAWPLQGWQA 207 >1BG5-A nrPDB Length = 254 Score = 190 bits (483), Expect = 4e-49, Method: Composition-based stats. Identities = 53/212 (25%), Positives = 86/212 (40%), Gaps = 7/212 (3%) Query: 4 KPKLHYFNGRGRMEPIRWLLAAAGVEFEEKFIG--SAEDLGKLRNDGSLMFQQVPMVEID 61 P L Y+ +G ++P R LL ++EE + + + L F +P Sbjct: 2 SPILGYWKIKGLVQPTRLLLEYLEEKYEEHLYERDEGDKWRNKKFELGLEFPNLPYYIDG 61 Query: 62 GMKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAKI 121 +KL Q+ AI+ YIA K+N+ G KERA I M + D+ + + + E + Sbjct: 62 DVKLTQSMAIIRYIADKHNMLGGCPKERAEISMLEGAVLDIRYGVSRIAYSKDFET---L 118 Query: 122 ALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLISNFPLL 181 + FE L + YL G+ ++ D L + L V +D + FP L Sbjct: 119 KVDFLSKLPEMLKMFEDRL--CHKTYLNGDHVTHPDFMLYDALDVVLYMDPMCLDAFPKL 176 Query: 182 KALKTRISNLPTVKKFLQPGSPRKPPADAKAL 213 K RI +P + K+L+ P Sbjct: 177 VCFKKRIEAIPQIDKYLKSSKYIAWPLQGWQA 208 >1M0U-A nrPDB Length = 249 Score = 187 bits (474), Expect = 5e-48, Method: Composition-based stats. Identities = 42/200 (21%), Positives = 95/200 (47%), Gaps = 6/200 (3%) Query: 4 KPKLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQVPMVEIDGM 63 L YFN + EP+R+L A E+E+ + + ++ L+ ++ Q+P++E+DG Sbjct: 49 SYTLFYFNVKALAEPLRYLFAYGNQEYEDVRV-TRDEWPALKP--TMPMGQMPVLEVDGK 105 Query: 64 KLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEE-KDAKIA 122 ++ Q+ ++ ++A L G E ID+ + + D I ++ +E K+ K+ Sbjct: 106 RVHQSISMARFLAKTVGLCGATPWEDLQIDIVVDTINDFRLKIAVVSYEPEDEIKEKKLV 165 Query: 123 LIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEEL-DSSLISNFPLL 181 + + Y E+ ++ + +G KL+ AD+ + Y+ + L+ +P L Sbjct: 166 TLNAEVIPFYLEKLEQTVKDNDGHLALG-KLTWADVYFAGITDYMNYMVKRDLLEPYPAL 224 Query: 182 KALKTRISNLPTVKKFLQPG 201 + + ++ L +K +++ Sbjct: 225 RGVVDAVNALEPIKAWIEKR 244 >1YQ1-A nrPDB Length = 208 Score = 182 bits (461), Expect = 1e-46, Method: Composition-based stats. Identities = 61/207 (29%), Positives = 98/207 (47%), Gaps = 13/207 (6%) Query: 3 GKPKLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQVPMVEIDG 62 KL YF RG EPIR L AGV+FEE + D L S +Q+P++ IDG Sbjct: 2 PSYKLTYFFFRGLGEPIRLLFHLAGVQFEEVRMN--PDQTWLDIKDSTPMKQLPVLNIDG 59 Query: 63 MKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAKIA 122 +L Q+ AIL Y+A K+ GK +E A +D + D + E + K A Sbjct: 60 FELPQSGAILRYLARKFGFAGKTPEEEAWVDAVHDLFKDF---LAEFKKFAAERRSGKSA 116 Query: 123 LIKEKTKSR--------YFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSL 174 EK +S YF +L+ +L+G+ ++ AD+ +V+ L ++ Sbjct: 117 EEVEKFRSEFFLPARNTYFNILNGLLEKSNSGFLIGSDITFADLVVVDNLLTLKNYGLFD 176 Query: 175 ISNFPLLKALKTRISNLPTVKKFLQPG 201 S F L AL+ ++++ P +K+++ Sbjct: 177 ESEFTKLAALREKVNSYPGIKEYIAKR 203 >4WR5-A nrPDB Length = 244 Score = 181 bits (459), Expect = 2e-46, Method: Composition-based stats. Identities = 51/214 (23%), Positives = 85/214 (39%), Gaps = 7/214 (3%) Query: 2 AGKPKLHYFNGRGRMEPIRWLLAAAGVEFEEKFIG--SAEDLGKLRNDGSLMFQQVPMVE 59 + P L Y+ +G ++P R LL ++EE + + + L F +P Sbjct: 24 SXSPILGYWKIKGLVQPTRLLLEXLEEKYEEHLXERDEGDKWRNKKFELGLEFPNLPYXI 83 Query: 60 IDGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDA 119 +KL Q+ AI+ IA K+N+ G KERA I M + D+ + + + E Sbjct: 84 DGDVKLTQSMAIIRXIADKHNMLGGCPKERAEISMLEGAVLDIRYGVSRIAYSKDFET-- 141 Query: 120 KIALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLISNFP 179 + + FE L + L G+ ++ D L + L V +D + FP Sbjct: 142 -LKVDFLSKLPEMLKMFEDRL--CHKTXLNGDHVTHPDFMLYDALDVVLXMDPMCLDAFP 198 Query: 180 LLKALKTRISNLPTVKKFLQPGSPRKPPADAKAL 213 L K RI +P + K+L+ P Sbjct: 199 KLVCFKKRIEAIPQIDKYLKSSKYIAWPLQGWQA 232 >2WDU-A nrPDB Length = 211 Score = 174 bits (442), Expect = 2e-44, Method: Composition-based stats. Identities = 52/205 (25%), Positives = 96/205 (46%), Gaps = 10/205 (4%) Query: 6 KLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQVPMVEIDG--- 62 KL YF RGR EPIR LL AGV+FE+ + + + ++ +L +VP++++ G Sbjct: 7 KLWYFQFRGRAEPIRLLLTCAGVKFED-YQFTMDQWPTIKP--TLPGGRVPLLDVTGPDG 63 Query: 63 --MKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAK 120 + ++ AI +A ++ + G+ +E LI+ DL + + EK+AK Sbjct: 64 KLRRYQESMAIARLLARQFKMMGETDEEYYLIERIIGECEDLYREVYTIFRTPQGEKEAK 123 Query: 121 IALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLIS-NFP 179 I KE + L+S G ++ GN+++ D+ L L +V E + FP Sbjct: 124 IKEFKENNGPTLLKLVSESLESSGGKHVAGNRITLGDLFLFTTLTHVMETVPGFLEQKFP 183 Query: 180 LLKALKTRI-SNLPTVKKFLQPGSP 203 L + ++ + ++L+ + Sbjct: 184 KLHEFHKSLPTSCSRLSEYLKKRAK 208 >2CA8-A nrPDB Length = 211 Score = 173 bits (439), Expect = 5e-44, Method: Composition-based stats. Identities = 54/205 (26%), Positives = 99/205 (48%), Gaps = 10/205 (4%) Query: 2 AGKPKLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQVPMVEID 61 K+ YFNGRGR E IR L AAGV +E++ I S +D K++ ++ ++P V+I Sbjct: 3 GDHIKVIYFNGRGRAESIRMTLVAAGVNYEDERI-SFQDWPKIKP--TIPGGRLPAVKIT 59 Query: 62 GMK-----LVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEE 116 +V++ AI Y+A K+++ G +E ++ DL + EE Sbjct: 60 DNHGHVKWMVESLAIARYMAKKHHMMGGTEEEYYNVEKLIGQAEDLEHEYYKTLMKPEEE 119 Query: 117 KDAKIALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLIS 176 K I I + L++ VG+K++ AD+ L+ ++ +V +LD ++ Sbjct: 120 KQKIIKEILNGKVPVLLDIICESLKASTGKLAVGDKVTLADLVLIAVIDHVTDLDKEFLT 179 Query: 177 -NFPLL-KALKTRISNLPTVKKFLQ 199 +P + K + +++ P + K+L Sbjct: 180 GKYPEIHKHRENLLASSPRLAKYLS 204 >1U3I-A nrPDB Length = 211 Score = 171 bits (434), Expect = 2e-43, Method: Composition-based stats. Identities = 55/213 (25%), Positives = 109/213 (51%), Gaps = 13/213 (6%) Query: 1 MAGKP-KLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQVPMVE 59 MAG+ K+ YF+GRGR E IR L AAGV++E++ I S +D K++ ++ ++P V+ Sbjct: 1 MAGEHIKVIYFDGRGRAESIRMTLVAAGVDYEDERI-SFQDWPKIKP--TIPGGRLPAVK 57 Query: 60 IDGMK-----LVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRP 114 + ++++ AI Y+A K+++ G+ +E ++ D+ + Sbjct: 58 VTDDHGHVKWMLESLAIARYMAKKHHMMGETDEEYYSVEKLIGQAEDVEHEYHKTLMKPQ 117 Query: 115 EEKDAKIALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSL 174 EEK+ I F + L+ VG+K++ AD+ L+ ++ +V +LD Sbjct: 118 EEKEKITKEILNGKVPVLFNMICESLKGSTGKLAVGDKVTLADLVLIAVIDHVTDLDKGF 177 Query: 175 IS-NFPLL-KALKTRISNLPTVKKFL--QPGSP 203 ++ +P + K + +++ P + K+L +P +P Sbjct: 178 LTGKYPEIHKHRENLLASSPRLAKYLSNRPATP 210 >2HNL-A nrPDB Length = 225 Score = 166 bits (421), Expect = 7e-42, Method: Composition-based stats. Identities = 55/202 (27%), Positives = 99/202 (49%), Gaps = 10/202 (4%) Query: 3 GKPKLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQVPMVEIDG 62 K L YFNGRGR E IR L A A V +E+ I + ++ L+ F VPM+ + G Sbjct: 26 EKYTLTYFNGRGRAEVIRLLFALANVSYEDNRI-TRDEWKYLKPR--TPFGHVPMLNVSG 82 Query: 63 MKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAKIA 122 L ++ AI + ++ L G + E A I + +L + + +P + K Sbjct: 83 NVLGESHAIELLLGGRFGLLGTNDWEEAKIMAVVLNIDELFQKL--IPWTHEKNTTKKAE 140 Query: 123 LIKEKTKSRYFPA---FEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLISNFP 179 L + ++S P +EK L+ ++VGNK+S AD+++ +L ++ D + +P Sbjct: 141 LFRNLSESDVMPFLGRYEKFLKESTTGHIVGNKVSVADLTVFNMLMTLD--DEVKLEEYP 198 Query: 180 LLKALKTRISNLPTVKKFLQPG 201 L + +I +P +K++++ Sbjct: 199 QLASFVNKIGQMPGIKEWIKKR 220 >2CZ2-A nrPDB Length = 223 Score = 160 bits (405), Expect = 5e-40, Method: Composition-based stats. Identities = 55/212 (25%), Positives = 102/212 (48%), Gaps = 12/212 (5%) Query: 2 AGKPKLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSL---MFQQVPMV 58 AGKP L+ + +R LA G+++E I +D G+ + +QVP + Sbjct: 10 AGKPILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPAL 69 Query: 59 EIDGMKLVQTRAILNYIASKY---NLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPE 115 +IDG+ +VQ+ AI+ Y+ L +D ++RA++ M ++ +A + + L + + Sbjct: 70 KIDGITIVQSLAIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQV 129 Query: 116 EKDAKIALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLI 175 ++ ++ +K + F A EK+LQS Y VG+++S AD+ LV + E + Sbjct: 130 GQENQMQWA-QKVITSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVANAERFKVD-L 187 Query: 176 SNFPLLKALKTRISNLPTVKKFLQPGSPRKPP 207 S +P + + + L Q PR+ P Sbjct: 188 SPYPTISHINKELLALE----VFQVSHPRRQP 215 >1FW1-A nrPDB Length = 216 Score = 157 bits (397), Expect = 3e-39, Method: Composition-based stats. Identities = 50/212 (23%), Positives = 99/212 (46%), Gaps = 12/212 (5%) Query: 2 AGKPKLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSL---MFQQVPMV 58 AGKP L+ + +R LA G++++ I +D G+ + +QVP + Sbjct: 3 AGKPILYSYFRSSCSWRVRIALALKGIDYKTVPINLIKDGGQQFSKDFQALNPMKQVPTL 62 Query: 59 EIDGMKLVQTRAILNYIASKY---NLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPE 115 +IDG+ + Q+ AI+ Y+ L +D K+RA + M ++ +A + + L + + Sbjct: 63 KIDGITIHQSLAIIEYLEETRPTPRLLPQDPKKRASVRMISDLIAGGIQPLQNLSVLKQV 122 Query: 116 EKDAKIALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLI 175 ++ ++ + F A E++LQS Y VG++++ AD+ LV + E + Sbjct: 123 GEEMQLTWAQNAITCG-FNALEQILQSTAGIYCVGDEVTMADLCLVPQVANAERFKVD-L 180 Query: 176 SNFPLLKALKTRISNLPTVKKFLQPGSPRKPP 207 + +P + ++ R+ L Q P + P Sbjct: 181 TPYPTISSINKRLLVLEA----FQVSHPCRQP 208 >5F07-A nrPDB Length = 213 Score = 125 bits (315), Expect = 1e-29, Method: Composition-based stats. Identities = 57/194 (29%), Positives = 88/194 (45%), Gaps = 21/194 (10%) Query: 23 LAAAGVEFEEKFIGSAEDLGKLRNDGSL---MFQQVPMVEIDGMKLVQTRAILNYIASKY 79 L GVEF+ + D G+ + L F QVP+VE KL ++RAI+ Y A+KY Sbjct: 20 LLEKGVEFDLVHVDL--DSGEQKLPEFLLKQPFGQVPVVEDGDFKLFESRAIIRYYAAKY 77 Query: 80 -----NLYGKDIKERALIDMYTE----GMADLNEMILLLPLCRP---EEKDAKIALIKEK 127 NL G ++E+AL+D + E DL I+ + P ++ D+++ E+ Sbjct: 78 EDRGPNLLGNTLEEKALVDQWLEIEAHNFNDLVFNIVFQVVILPRIGQQGDSELVRTYEE 137 Query: 128 TKSRYFPAFEKVLQSHGQDYLVGNKLSRADI-SLVELLYYVEELD-SSLISNFPLLKALK 185 + +EK L YL G+ + AD+ L Y V E L+ + L A Sbjct: 138 KLEKVLDVYEKRLSKS--KYLAGDSFTLADLSHLPATRYLVNEAGLGHLVKDRKKLNAWW 195 Query: 186 TRISNLPTVKKFLQ 199 IS+ P KK + Sbjct: 196 EDISSRPAWKKLMN 209 >4PNG-A nrPDB Length = 229 Score = 124 bits (311), Expect = 3e-29, Method: Composition-based stats. Identities = 46/184 (25%), Positives = 82/184 (44%), Gaps = 11/184 (5%) Query: 17 EPIRWLLAAAGVEFEEKFIGSA--EDLGKLRNDGSLMFQQVPMVEIDGMKLVQTRAILNY 74 ++ LAA V +E + + E+ + + VP +E DG + + AI+ Y Sbjct: 22 RAVKLTLAALEVPYEFVEVNTRAKENFSEEFLKKN-PQHTVPTLEDDGHYIWDSHAIIAY 80 Query: 75 IASKYN----LYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAKIALIKEK--T 128 + SKY LY KD+ +RA++D + + L + +P + + KE+ Sbjct: 81 LVSKYGKTDSLYPKDLLQRAVVDQRLHFESGVIFANALRSITKPLFAGKQTMIPKERYDA 140 Query: 129 KSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLISNFPLLKALKTRI 188 + EK L G DY+ GN+L+ AD S++ + +E + +P + A R+ Sbjct: 141 IIEVYDFLEKFLA--GNDYVAGNQLTIADFSIISTVSSLEVFVKVDTTKYPRIAAWFKRL 198 Query: 189 SNLP 192 LP Sbjct: 199 QKLP 202 >3VWX-A nrPDB Length = 222 Score = 115 bits (289), Expect = 1e-26, Method: Composition-based stats. Identities = 50/187 (26%), Positives = 79/187 (42%), Gaps = 16/187 (8%) Query: 18 PIR---WLLAAAGVEFEEKFIGS-AEDLGKLRNDGSLMFQQVPMVEIDGMKLVQTRAILN 73 P+R L A + FE K + A++ VP +E DG + + AI+ Sbjct: 14 PVRACLLTLKALNLPFEYKVVNLFAKEHLSEEYLKKNPQHTVPTLEEDGHLIWDSHAIMA 73 Query: 74 YIASKYN----LYGKDIKERALID--MYTEGMADLNEMILLL--PLCRPEEKDAKIALIK 125 Y+ SKY LY KD+ +RA++D MY E + + PL + I Sbjct: 74 YLVSKYGKDDSLYPKDLLKRAVVDQRMYFEAGVLFQGGLRNITAPLFFRNQTQIPQHQID 133 Query: 126 EKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLISNFPLLKALK 185 +S F E L+++ Y+ G+ L+ AD S+V + + S FP L A Sbjct: 134 SIVESYGF--LESFLKNN--KYMAGDHLTIADFSIVTSVTSLVAFAEIDQSKFPKLSAWL 189 Query: 186 TRISNLP 192 + +LP Sbjct: 190 KSLQSLP 196 >4YH2-A nrPDB Length = 222 Score = 114 bits (287), Expect = 2e-26, Method: Composition-based stats. Identities = 44/189 (23%), Positives = 78/189 (41%), Gaps = 21/189 (11%) Query: 17 EPIRWLLAAAGVEFEEK------FIGSAEDLGKLRNDGSLMFQQVPMVEIDGMKLVQTRA 70 ++ LAA + +E + + + VP +E DG + + A Sbjct: 16 RAVKLTLAALNLTYEYVNVDIVARAQLSPEYLEKNPQ-----HTVPTLEDDGHYIWDSHA 70 Query: 71 ILNYIASKYN----LYGKDIKERALIDM---YTEGMADLNEMILLLPLCRPEEKDAKIAL 123 I+ Y+ SKY LY KD +RA++D + G+ I + + K+ Sbjct: 71 IIAYLVSKYADSDALYPKDPLKRAVVDQRLHFESGVV-FANGIRSISKSVLFQGQTKVPK 129 Query: 124 IKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLISNFPLLKA 183 + + E L+ GQDY+ GN+L+ AD SLV + +E + + +P + A Sbjct: 130 ERYDAIIEIYDFVETFLK--GQDYIAGNQLTIADFSLVSSVASLEAFVALDTTKYPRIGA 187 Query: 184 LKTRISNLP 192 ++ LP Sbjct: 188 WIKKLEQLP 196 >5F06-A nrPDB Length = 216 Score = 111 bits (278), Expect = 2e-25, Method: Composition-based stats. Identities = 51/201 (25%), Positives = 89/201 (44%), Gaps = 23/201 (11%) Query: 23 LAAAGVEFEEKFIGSAEDLGKLRNDGSL---MFQQVPMVEIDGMKLVQTRAILNYIASKY 79 L ++FE + G+ + L F Q+P +E D + L ++RAI +YIA K+ Sbjct: 20 LHEKNLDFELVPVDLFA--GEHKQPPFLAKNPFGQIPALEEDDLTLFESRAITSYIAEKF 77 Query: 80 NLYG------KDIKERALIDMYTE--------GMADLNEMILLLPLCRPEEKDAKIALIK 125 G +++KE A + ++TE +A + ++ PL R D I Sbjct: 78 KGTGYDLIRHENLKEAASVKVWTEVESHRYNPAIAPIVFQFMVAPL-RGNSPDQTIIDDN 136 Query: 126 EKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELD-SSLISNFPLLKAL 184 + + +E L S YL G+ S AD+ + YY+ + +S+++ P +KA Sbjct: 137 VEKLGKVLDIYEAKLSS--TKYLAGDFYSLADLHHLPYTYYLMKTPAASVVNERPHVKAW 194 Query: 185 KTRISNLPTVKKFLQPGSPRK 205 IS+ P KK + + K Sbjct: 195 WEDISSRPAFKKVAEGMNFVK 215 >5EY6-A nrPDB Length = 217 Score = 108 bits (269), Expect = 3e-24, Method: Composition-based stats. Identities = 40/178 (22%), Positives = 69/178 (38%), Gaps = 24/178 (13%) Query: 38 AEDLGKLRNDGSLMFQQVPMVEIDGMKLVQTRAILNYIASKY------NLYGKDIKERAL 91 D K++ F QVP + + + L ++R+I Y+ KY LYG + ERA Sbjct: 43 KPDYLKIQ-----PFGQVPAFQDESISLFESRSICRYVCEKYADRGDKGLYGTNPLERAS 97 Query: 92 IDMYTEGMAD--------LNEMILLLPLCRPEEKDAKIALIKEKTKSRYFPAFEKVLQSH 143 ID + E L + P + I E+ + +E+ L Sbjct: 98 IDQWVEAEGQSFGPSSGALVFQLAFAPRMNIPQDQGVIKQ-NEEKLGKVLDIYEQRLGES 156 Query: 144 GQDYLVGNKLSRADI-SLVELLYYVEELDS-SLISNFPLLKALKTRISNLPTVKKFLQ 199 +L G++ + AD+ L Y V D L ++ + IS+ + KK ++ Sbjct: 157 --RFLAGDEFTFADLSHLPNGDYLVNATDKGHLFTSRENVGRWWNEISDRESWKKVIE 212 >5F0G-A nrPDB Length = 215 Score = 104 bits (260), Expect = 3e-23, Method: Composition-based stats. Identities = 44/188 (23%), Positives = 84/188 (44%), Gaps = 18/188 (9%) Query: 7 LHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQ--VPMVEIDGMK 64 +Y G G + + A G+E +K + + E +L+ + + Q +P + +G Sbjct: 3 FYYMPGGGGCRTVIMVAKALGLELNKKLLNTME-GEQLKPEFVKLNPQHTIPTLVDNGFS 61 Query: 65 LVQTRAILNYIASKYN----LYGKDIKERALIDM--YTEGMADLNEMI--LLLPLCRPEE 116 + ++RAI Y+ KY L D K+RA+I+ Y + M L E PL R + Sbjct: 62 IWESRAIAVYLVEKYGKDDYLLPNDPKKRAVINQRLYFD-MGTLYESFAKYYYPLFRTGK 120 Query: 117 KDAKIALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLIS 176 + L + +T + F + GQ+Y+ G++L+ ADI+++ + E + S Sbjct: 121 PGSDEDLKRIETAFGFLDTFLE-----GQEYVAGDQLTVADIAILSTVSTFEVSEFD-FS 174 Query: 177 NFPLLKAL 184 + + Sbjct: 175 KYSNVSRW 182 >4RI7-A nrPDB Length = 215 Score = 104 bits (260), Expect = 3e-23, Method: Composition-based stats. Identities = 45/165 (27%), Positives = 68/165 (41%), Gaps = 22/165 (13%) Query: 51 MFQQVPMVEIDGMKLVQTRAILNYIASKY------NLYGKDIKERALIDMYTEG------ 98 F QVP + + + L ++RAI YI KY +LYG DI +A ID + E Sbjct: 52 PFGQVPAFKDESITLFESRAICRYICDKYADKGNKSLYGTDILSKANIDQWVETDGQTFG 111 Query: 99 --MADLNEMILLLPLCRPEEKDAKIALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRA 156 DL +L + E K ++ +E+ L +L G++ S A Sbjct: 112 PPSGDLVHDLLFSSVPVDEALIKK----NVDKLAKVLDIYEQKLGQ--TRFLAGDEFSFA 165 Query: 157 DI-SLVELLYYVEELDSS-LISNFPLLKALKTRISNLPTVKKFLQ 199 D+ L Y V D L ++ + T ISN + KK L+ Sbjct: 166 DLSHLPNGDYLVNSTDKGYLFTSRKNVNRWWTEISNRESWKKVLE 210 >1AXD-A nrPDB Length = 209 Score = 100 bits (250), Expect = 5e-22, Method: Composition-based stats. Identities = 45/190 (23%), Positives = 83/190 (43%), Gaps = 20/190 (10%) Query: 23 LAAAGVEFEEKFIGSAEDLGKLRNDGSL---MFQQVPMVEIDGMKLVQTRAILNYIASKY 79 L AG ++E I A + ++ L F QVP ++ + L ++RAI Y A K Sbjct: 21 LEEAGSDYEIVPINFAT--AEHKSPEHLVRNPFGQVPALQDGDLYLFESRAICKYAARKN 78 Query: 80 N---LYGKDIKERALIDMYTE--------GMADLNEMILLLPLCRPEEKDAKIALIKEKT 128 L +++E A++D++ E + + +L+ P+ D K+ + Sbjct: 79 KPELLREGNLEEAAMVDVWIEVEANQYTAALNPILFQVLISPML-GGTTDQKVVDENLEK 137 Query: 129 KSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVE-LLYYVEELDSSLISNFPLLKALKTR 187 + +E L YL G+ LS AD++ V L +S++ +P +KA + Sbjct: 138 LKKVLEVYEARLTKC--KYLAGDFLSLADLNHVSVTLCLFATPYASVLDAYPHVKAWWSG 195 Query: 188 ISNLPTVKKF 197 + P+V+K Sbjct: 196 LMERPSVQKV 205 >1PN9-A nrPDB Length = 209 Score = 98.0 bits (243), Expect = 3e-21, Method: Composition-based stats. Identities = 45/192 (23%), Positives = 74/192 (38%), Gaps = 14/192 (7%) Query: 7 LHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQ--VPMVEIDGMK 64 +Y G ++ AA GVE K + ++ + + Q +P + +G Sbjct: 3 FYYLPGSAPCRAVQMTAAAVGVELNLKLTDLMK-GEHMKPEFLKLNPQHCIPTLVDNGFA 61 Query: 65 LVQTRAILNYIASKYN----LYGKDIKERALIDM--YTEGMADLNEMILLLPLCRPEEKD 118 L ++RAI Y+A KY LY KD ++RA+++ Y + M L + Sbjct: 62 LWESRAIQIYLAEKYGKDDKLYPKDPQKRAVVNQRLYFD-MGTLYQRFADYHY-PQIFAK 119 Query: 119 AKIALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLISNF 178 EK L+ GQ+Y GN L+ AD+SL + E + + Sbjct: 120 QPANPENEKKMKDAVGFLNTFLE--GQEYAAGNDLTIADLSLAATIATYEV-AGFDFAPY 176 Query: 179 PLLKALKTRISN 190 P + A R Sbjct: 177 PNVAAWFARCKA 188 >1JLV-A nrPDB Length = 209 Score = 96.1 bits (238), Expect = 1e-20, Method: Composition-based stats. Identities = 37/187 (19%), Positives = 68/187 (36%), Gaps = 10/187 (5%) Query: 7 LHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQ--VPMVEIDGMK 64 +Y G ++ AA GVE K ++ + + Q +P + +G Sbjct: 3 FYYLPGSAPCRAVQMTAAAVGVELNLKLTNLMA-GEHMKPEFLKINPQHCIPTLVDNGFA 61 Query: 65 LVQTRAILNYIASKYN----LYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAK 120 L ++RAI Y+A KY LY KD ++RA+++ Sbjct: 62 LWESRAICTYLAEKYGKDDKLYPKDPQKRAVVNQRLYFDMGTLYQRFADYYYPQIFAKQP 121 Query: 121 IALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLISNFPL 180 EK L H Y+ G+ L+ AD++++ + + ++ +P Sbjct: 122 ANAENEKKMKDAVDFLNTFLDGH--KYVAGDSLTIADLTVLATVSTYDVAGFE-LAKYPH 178 Query: 181 LKALKTR 187 + A R Sbjct: 179 VAAWYER 185 >6F05-A nrPDB Length = 215 Score = 94.2 bits (233), Expect = 4e-20, Method: Composition-based stats. Identities = 44/194 (22%), Positives = 81/194 (41%), Gaps = 27/194 (13%) Query: 23 LAAAGVEFEEKFIGSAEDLGKLRNDGSL---MFQQVPMVEIDGMKLVQTRAILNYIASKY 79 L GV FE + + G+ + L F VP V K+ ++RA++ Y+A KY Sbjct: 20 LIEKGVAFETIPVDLMK--GEHKQPAYLALQPFGTVPAVVDGDYKIFESRAVMRYVAEKY 77 Query: 80 -----NLYGKDIKERALIDMYTEGMA----------DLNEMILLLPLCRPEEKDAKIALI 124 +L GK +++R ++ + + A L+ M + +EK K + Sbjct: 78 RSQGPDLLGKTVEDRGQVEQWLDVEATTYHPPLLNLTLHIMFASVMGFPSDEKLIKES-- 135 Query: 125 KEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVE--ELDSSLISNFPLLK 182 E+ + +E L YL G+ +S AD++ + Y+ + +I + + Sbjct: 136 -EEKLAGVLDVYEAHLSKS--KYLAGDFVSLADLAHLPFTDYLVGPIGKAYMIKDRKHVS 192 Query: 183 ALKTRISNLPTVKK 196 A IS+ P K+ Sbjct: 193 AWWDDISSRPAWKE 206 >5ZWP-A nrPDB Length = 208 Score = 93.8 bits (232), Expect = 5e-20, Method: Composition-based stats. Identities = 37/184 (20%), Positives = 64/184 (34%), Gaps = 10/184 (5%) Query: 7 LHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRND--GSLMFQQVPMVEIDGMK 64 +Y G + A G+E +K + L+ + +P + Sbjct: 3 FYYLPGSAPCRSVLMTAKALGIELNKKLLNLQA-GEHLKPEFLKINPQHTIPTLVDGDFA 61 Query: 65 LVQTRAILNYIASKYN----LYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAK 120 L ++RAI+ Y+ KY L+ K K+RA+I+ A Sbjct: 62 LWESRAIMVYLVEKYGKTDSLFPKCPKKRAVINQRLYFDMGTLYKSFADYYYPQIFAKAP 121 Query: 121 IALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLISNFPL 180 K F L+ H +Y G+ L+ AD++L+ + E S IS +P Sbjct: 122 ADPELFKKIETAFDFLNTFLKGH--EYAAGDSLTVADLALLASVSTFEV-ASFDISKYPN 178 Query: 181 LKAL 184 + Sbjct: 179 VAKW 182 >1AW9-A nrPDB Length = 216 Score = 93.4 bits (231), Expect = 7e-20, Method: Composition-based stats. Identities = 48/206 (23%), Positives = 82/206 (39%), Gaps = 28/206 (13%) Query: 22 LLAAAGVEFEEKFIGS------AEDLGKLRNDGSLMFQQVPMVEIDGMKLVQTRAILNYI 75 +L G++FE + D L F Q+P + L ++RAI YI Sbjct: 20 VLNEKGLDFEIVPVDLTTGAHKQPDFLALN-----PFGQIPALVDGDEVLFESRAINRYI 74 Query: 76 ASKYNLYGKDIK----ERALIDMYTE--------GMADLNEMILLLPLCRPEEKDAKIAL 123 ASKY G D+ A ++++ E + L +L+ PL DA + Sbjct: 75 ASKYASEGTDLLPATASAAKLEVWLEVESHHFYPNASPLVFQLLVRPLL-GGAPDAAVVD 133 Query: 124 IKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEEL-DSSLISNFPLLK 182 + ++ +E L + YL G++ + AD + L Y+ + + L++ P +K Sbjct: 134 KHAEQLAKVLDVYEAHLARN--KYLAGDEFTLADANHASYLLYLSKTPKAGLVAARPHVK 191 Query: 183 ALKTRISNLPTVKKFLQPGSPRKPPA 208 A I P +K + P PP Sbjct: 192 AWWEAIVARPAFQKTVA-AIPLPPPP 216 >3MAK-A nrPDB Length = 209 Score = 93.4 bits (231), Expect = 8e-20, Method: Composition-based stats. Identities = 42/186 (22%), Positives = 64/186 (34%), Gaps = 10/186 (5%) Query: 7 LHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRND--GSLMFQQVPMVEIDGMK 64 +Y G + A GVE +K + L+ + +P + +G Sbjct: 4 FYYLPGSSPCRSVIMTAKAVGVELNKKLLNLQA-GEHLKPEFLKINPQHTIPTLVDNGFA 62 Query: 65 LVQTRAILNYIASKYN----LYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAK 120 L ++RAI Y+ KY LY K K+RA+I+ A Sbjct: 63 LWESRAIQVYLVEKYGKTDSLYPKCPKKRAVINQRLYFDMGTLYQSFANYYYPQVFAKAP 122 Query: 121 IALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLISNFPL 180 K F L+ GQDY G+ L+ ADI+LV + E IS + Sbjct: 123 ADPEAFKKIEAAFEFLNTFLE--GQDYAAGDSLTVADIALVATVSTFEVAKFE-ISKYAN 179 Query: 181 LKALKT 186 + Sbjct: 180 VNRWYE 185 >2IL3-A nrPDB Length = 221 Score = 93.0 bits (230), Expect = 9e-20, Method: Composition-based stats. Identities = 35/186 (18%), Positives = 75/186 (40%), Gaps = 15/186 (8%) Query: 16 MEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQ--VPMVEIDGMKLVQTRAILN 73 + A G+E E+K I L+ + + Q +P+++ +G + ++ AI+ Sbjct: 15 CRAVELTAKALGLELEQKTINLL-TGDHLKPEFVKLNPQHTIPVLDDNGTIITESHAIMI 73 Query: 74 YIASKYN----LYGKDIKERALIDM---YTEGMADLNEMILLLPLCRPEEKDAKIALIKE 126 Y+ +KY LY KD ++A ++ + G+ + + + I + Sbjct: 74 YLVTKYGKDDSLYPKDPVKQARVNSALHFESGVLFARMRFIFERILF--FGKSDIPEDRV 131 Query: 127 KTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLISNFPLLKALKT 186 + + + E L D++ G ++ AD S + + + + S P + A Sbjct: 132 EYVQKSYELLEDTLVD---DFVAGPTMTIADFSCISTISSIMGVVPLEQSKHPRIYAWID 188 Query: 187 RISNLP 192 R+ LP Sbjct: 189 RLKQLP 194 >1E6B-A nrPDB Length = 221 Score = 90.3 bits (223), Expect = 7e-19, Method: Composition-based stats. Identities = 39/212 (18%), Positives = 80/212 (37%), Gaps = 9/212 (4%) Query: 3 GKPKLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGS-AEDLGKLRNDGSLMFQQVPMVEID 61 K KL+ + +R LA G+++E + D VP + Sbjct: 7 EKLKLYSYWRSSCAHRVRIALALKGLDYEYIPVNLLKGDQFDSDFKKINPMGTVPALVDG 66 Query: 62 GMKLVQTRAILNYIASKY---NLYGKDIKERAL----IDMYTEGMADLNEMILLLPLCRP 114 + + + AI+ Y+ KY L +D+ +RA+ + + G+ + ++ + Sbjct: 67 DVVINDSFAIIMYLDEKYPEPPLLPRDLHKRAVNYQAMSIVLSGIQPHQNLAVIRYIEEK 126 Query: 115 EEKDAKIALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSL 174 + K A + ++ F A EK+L + + G+++ AD+ L ++ Sbjct: 127 INVEEKTAWVNN-AITKGFTALEKLLVNCAGKHATGDEIYLADLFLAPQIHGAINRFQIN 185 Query: 175 ISNFPLLKALKTRISNLPTVKKFLQPGSPRKP 206 + +P L + LP + L P P Sbjct: 186 MEPYPTLAKCYESYNELPAFQNALPEKQPDAP 217 >5A5K-A nrPDB Length = 212 Score = 84.2 bits (207), Expect = 4e-17, Method: Composition-based stats. Identities = 42/212 (19%), Positives = 73/212 (34%), Gaps = 24/212 (11%) Query: 1 MAGKPKLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSL---MFQQVPM 57 MAG + + L ++FE + + G+ + + L F QVP Sbjct: 1 MAGIKVFGH-PASIATRRVLIALHEKNLDFELVHVELKD--GEHKKEPFLSRNPFGQVPA 57 Query: 58 VEIDGMKLVQTRAILNYIASKY-----NLYGKDIKE--RALIDMYTEGMADLNEMILLLP 110 E +KL ++RAI YIA +Y NL D K + I + D + Sbjct: 58 FEDGDLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASK 117 Query: 111 LCRPE--------EKDAKIALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVE 162 L + D + +E ++ +E L+ YL G + D+ + Sbjct: 118 LAFEQIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEF--KYLAGETFTLTDLHHIP 175 Query: 163 LLYYVEELD-SSLISNFPLLKALKTRISNLPT 193 + Y+ L + P + I+ P Sbjct: 176 AIQYLLGTPTKKLFTERPRVNEWVAEITKRPA 207 >4IGJ-A nrPDB Length = 242 Score = 83.8 bits (206), Expect = 5e-17, Method: Composition-based stats. Identities = 44/214 (20%), Positives = 82/214 (38%), Gaps = 18/214 (8%) Query: 9 YFNGRGRMEPIRWLLAAAGVEFEEKFIGS-AEDLGKLRNDGSLMFQQVPMVEI--DGMK- 64 Y+ +R LA G+ +E + + A++ + + QVP++E+ DG Sbjct: 30 YWRSSS-AWRVRLGLALKGLAYEYRAVDLLAQEQFQAAHQARNPMSQVPVLEVEEDGRTH 88 Query: 65 -LVQTRAILNYIASKY---NLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEK--- 117 LVQ+ AIL ++ ++ L D+ RA + E + + + + R + Sbjct: 89 LLVQSMAILEWLEERHPEPALLPPDLWGRARVRALAEHVNSGTQPMQNALVLRMLREKVP 148 Query: 118 --DAKIALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLI 175 D + A +R A E ++ + G+ + AD LV LY + Sbjct: 149 GWDREWARFF---IARGLAALETAVRDGAGRFSHGDAPTLADCYLVPQLYNARRFGLD-L 204 Query: 176 SNFPLLKALKTRISNLPTVKKFLQPGSPRKPPAD 209 +P L+ + + L + P PP D Sbjct: 205 EPYPTLRRVDEACAALAPFQAAHPDRQPDAPPPD 238 >5F05-A nrPDB Length = 212 Score = 79.9 bits (196), Expect = 7e-16, Method: Composition-based stats. Identities = 37/195 (18%), Positives = 66/195 (33%), Gaps = 19/195 (9%) Query: 20 RWLLAAAGVEFEEKFIGSAEDLGKLRNDGSL---MFQQVPMVEIDGMKLVQTRAILNYIA 76 R L E E + + G+ + + + F QVP +KL ++RAI Y+A Sbjct: 16 RVLATLYEKEVEFELVNVNLGAGEHKQEPHISLNPFGQVPAAVDGDLKLFESRAISQYVA 75 Query: 77 SKYNLYGKDI------------KERALIDMYTEGMADLNEMILLLPLCRPEEKDAKIALI 124 +Y G + + + + L + P+ DA + Sbjct: 76 HQYASKGTQLGAAGNGYATILVWQEVESHQFDPSASKLVWEQVFKPVF-GLPTDAALVAE 134 Query: 125 KEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELD-SSLISNFPLLKA 183 E T + +E L YL + + AD+ + + + L + P + A Sbjct: 135 TEVTLGKVLDVYEARLSQS--KYLASDSFTLADLHHLPNIQALLGTPSKKLFDSRPHVSA 192 Query: 184 LKTRISNLPTVKKFL 198 I+ P K L Sbjct: 193 WVASITGRPAWGKVL 207 >4MPF-A nrPDB Length = 266 Score = 79.9 bits (196), Expect = 8e-16, Method: Composition-based stats. Identities = 42/203 (20%), Positives = 78/203 (38%), Gaps = 21/203 (10%) Query: 9 YFNGRGR-------MEPIR--WLLAAA-GVEFEEKFIGSAEDLGKLRNDGSL-MFQQVPM 57 YF G +P R ++ A G+ E + + + K + + ++P Sbjct: 19 YFQSMGLELFLDLVSQPSRAVYIFAKKNGIPLELRTVDLVKGQHKSKEFLQINSLGKLPT 78 Query: 58 VEIDGMKLVQTRAILNYIASKY----NLYGKDIKERALIDMYTEGMADLNEMILLLPLCR 113 ++ L ++ AIL Y++ KY + Y D++ RA + Y AD +PL Sbjct: 79 LKDGDFILTESSAILIYLSCKYQTPDHWYPSDLQARARVHEYLGWHADCIRGTFGIPLWV 138 Query: 114 PEEKDAKIALIKEKTKSRYFPAFEKVLQ------SHGQDYLVGNKLSRADISLVELLYYV 167 + ++ R A ++ LQ + +L G +++ AD+ +E L Sbjct: 139 QVLGPLIGVQVPKEKVERNRTAMDQALQWLEDKFLGDRPFLAGQQVTLADLMALEELMQP 198 Query: 168 EELDSSLISNFPLLKALKTRISN 190 L L P L A + R+ Sbjct: 199 VALGYELFEGRPRLAAWRGRVEA 221 >1V2A-A nrPDB Length = 210 Score = 78.8 bits (193), Expect = 2e-15, Method: Composition-based stats. Identities = 33/189 (17%), Positives = 72/189 (38%), Gaps = 12/189 (6%) Query: 8 HYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQVPMVEIDGMKLVQ 67 +Y + L G+ K + + + +P + +G + + Sbjct: 4 YYSLISPPCQSAILLAKKLGITLNLKKTNVHDPVERDALTKLNPQHTIPTLVDNGHVVWE 63 Query: 68 TRAILNYIASKYN----LYGKDIKERALIDM--YTEGMADLNEMILLLPLCRPEEKDAKI 121 + AI+ Y+ Y LY KD K R++++ + + +I ++ L +E+ + Sbjct: 64 SYAIVLYLVETYAKDDTLYPKDPKVRSVVNQRLFFDIGTLYKRIIDVIHLVMKKEQPSDE 123 Query: 122 ALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLISNFPLL 181 + K K E+ + + Y + L+ ADI L+ + + L + FP + Sbjct: 124 QMEKLK---GALDLLEQFVTE--RAYAAADHLTVADICLLGTVTALNWLK-HDLEPFPHI 177 Query: 182 KALKTRISN 190 +A R+ Sbjct: 178 RAWLERVRA 186 >3LSZ-A nrPDB Length = 225 Score = 78.8 bits (193), Expect = 2e-15, Method: Composition-based stats. Identities = 49/210 (23%), Positives = 83/210 (39%), Gaps = 25/210 (11%) Query: 13 RGRMEPIRWLLAAAGVEFEEKFIGSA-----EDLGKLRNDGSL-------MFQQVPMVEI 60 R R WLLA + FE + A + + + Q+P +E Sbjct: 10 RSRASRPLWLLAELDLPFEHVPVIQANRVAHPHGPEAPLNTASAAYLAVNPLGQIPCLEE 69 Query: 61 DGMKLVQTRAILNYIASKYN--LYGKDIKERALIDMYTEGMADLNE-------MILLLPL 111 +G+ L ++ AI +IA L + E AL+ ++ A E +I Sbjct: 70 EGLILTESLAITLHIARTQGGQLGPRSEPEDALMVSWSLFAATAVEPPALEIQLIQRSGG 129 Query: 112 CRPEEKDAKIALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELD 171 E A IA+ E+ + R E+ +DYLVG + + AD++L E L Y + Sbjct: 130 GTSPEGQAAIAIAAERLR-RPLARLERHFA--AEDYLVGGRFTVADLNLAETLRYGQAH- 185 Query: 172 SSLISNFPLLKALKTRISNLPTVKKFLQPG 201 +L+ FP + A R + P + ++ Sbjct: 186 PALLEPFPAVAAWLDRCQSRPAFRLMMERR 215 >3GH6-A nrPDB Length = 210 Score = 78.0 bits (191), Expect = 3e-15, Method: Composition-based stats. Identities = 38/189 (20%), Positives = 64/189 (33%), Gaps = 15/189 (7%) Query: 7 LHYFNGRGRMEPIRWLLAAAGVEFEEKFI---GSAEDL--GKLRNDGSLMFQQVPMVEID 61 L+Y G + A GVEF++K I + E L+ + +P + Sbjct: 3 LYYRPGSAPCRSVLMTAKALGVEFDKKTIINTRAREQFTPEYLKINPQ---HTIPTLHDH 59 Query: 62 GMKLVQTRAILNYIASKYN----LYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEK 117 G L ++RAI+ Y+ KY L+ KD++++ALI+ Sbjct: 60 GFALWESRAIMVYLVEKYGKDDKLFPKDVQKQALINQRLYFDMGTLYKSFSEYYYPQIFL 119 Query: 118 DAKIALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLISN 177 K F L+ GQ Y G S ADI+ + + + Sbjct: 120 KKPANEENYKKIEVAFEFLNTFLE--GQTYSAGGDYSLADIAFLATVSTFDV-AGFDFKR 176 Query: 178 FPLLKALKT 186 + + Sbjct: 177 YANVARWYE 185 >3M8N-A nrPDB Length = 225 Score = 76.8 bits (188), Expect = 6e-15, Method: Composition-based stats. Identities = 38/198 (19%), Positives = 69/198 (34%), Gaps = 11/198 (5%) Query: 5 PKLHYFNGRGRMEPIRWLLAAAGVEFEEKFIG-SAEDLGKLRNDGSLMFQQVPMVEID-G 62 KL+ G +R LA + + + QVP++E G Sbjct: 4 YKLYSMQRSGNSYKVRLALALLDAPYRAVEVDILRGESRTPDFLAKNPSGQVPLLETAPG 63 Query: 63 MKLVQTRAILNYIASKYNLYGKDIKERALIDMY----TEGMADLNEMILLLPLCRPEEKD 118 L ++ AIL Y+A +L +RA + + +D Sbjct: 64 RYLAESNAILWYLAVGTSLAPDTRMDRAEALQWMFFEQHALEPNIGSAYFWLCLVKGGRD 123 Query: 119 AKIALIKEKTKSRY--FPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLIS 176 + +++ + Y E L+++ DY +L+ ADI+L +V + +S Sbjct: 124 LQTHALEDWLERGYAALQVMENHLKTN--DYFAAGQLTIADIALYGYT-HVADQCDFDLS 180 Query: 177 NFPLLKALKTRISNLPTV 194 FP + A R+ P Sbjct: 181 TFPAVNAWLRRVEQTPGF 198 >3M3M-A nrPDB Length = 210 Score = 75.7 bits (185), Expect = 2e-14, Method: Composition-based stats. Identities = 41/190 (21%), Positives = 73/190 (38%), Gaps = 14/190 (7%) Query: 13 RGRMEPIRWLLAAAGVEFEEKFIG-SAEDLGKLRNDGSLMFQQVPMVE-IDGMKLVQTRA 70 G I+ +L G+ +E + + D ++P++E DG L ++ A Sbjct: 12 SGNCYKIKLMLNLLGLPYEWQAVDILGGDTQTEAFLAKNPNGKIPVLELEDGTCLWESNA 71 Query: 71 ILNYIASKYNLYGKDIKERALIDMY-------TEGMADLNEMILLLPLCRPEEKDAKIAL 123 ILN++A + + R + + E + I L E ++ + L Sbjct: 72 ILNFLADGSQFLPSEPRLRTQVLQWQFFEQYSHEPYIAVARFIQLYEGLPEERREEYLKL 131 Query: 124 IKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLISNFPLLKA 183 K + EK L YLVG S ADI+L +V + +S +P ++A Sbjct: 132 --HKRGYKALDVMEKQLSR--TPYLVGEHYSIADIALYAYT-HVADEGGFDLSRYPGIQA 186 Query: 184 LKTRISNLPT 193 R+ + P Sbjct: 187 WMQRVQSHPR 196 >2C3Q-A nrPDB Length = 247 Score = 74.5 bits (182), Expect = 3e-14, Method: Composition-based stats. Identities = 31/153 (20%), Positives = 57/153 (37%), Gaps = 15/153 (9%) Query: 51 MFQQVPMVEIDGMKLVQTRAILNYIASKYNL----YGKDIKERALIDMYTE-GMADLNE- 104 ++VP ++ L ++ AIL Y+ KY + Y +D++ RA +D Y L Sbjct: 57 PLKKVPALKDGDFTLTESVAILLYLTRKYKVPDYWYPQDLQARARVDEYLAWQHTTLRRS 116 Query: 105 ------MILLLPLCRPEEKDAKIALIKEKTKSRYFPAFE-KVLQSHGQDYLVGNKLSRAD 157 ++ P+ E + E K LQ+ + +L G +S AD Sbjct: 117 CLRALWHKVMFPVFLGEPVSPQTLAATLAELDVTLQLLEDKFLQN--KAFLTGPHISLAD 174 Query: 158 ISLVELLYYVEELDSSLISNFPLLKALKTRISN 190 + + L + + P L + R+ Sbjct: 175 LVAITELMHPVGAGCQVFEGRPKLATWRQRVEA 207 >3UAR-A nrPDB Length = 227 Score = 74.5 bits (182), Expect = 3e-14, Method: Composition-based stats. Identities = 53/205 (25%), Positives = 86/205 (41%), Gaps = 20/205 (9%) Query: 6 KLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQV------PMVE 59 KL+YF G + P +L AG++FE + + DLG + F QV P ++ Sbjct: 4 KLYYFPGACSLAP-HIVLREAGLDFELENV----DLGTKKTGSGADFLQVNPKGYVPALQ 58 Query: 60 -IDGMKLVQTRAILNYIAS---KYNLYGKD-IKERALIDMYTEGMADLNEMILLLPLCRP 114 DG L + + IL Y+A + L ER + + ++ P P Sbjct: 59 LDDGQVLTEDQVILQYLADLKPESGLMPPSGTFERYRLLEWLAFISTEIHKT-FGPFWNP 117 Query: 115 EEKDAKIALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSL 174 E +A I SR E L++ G +L+G++ S AD L +L + E L Sbjct: 118 ESPEAS-KQIALGLLSRRLDYVEDRLEA-GGPWLMGDRYSVADAYLSTVLGWCEYLKID- 174 Query: 175 ISNFPLLKALKTRISNLPTVKKFLQ 199 +S +P + A R P V+ ++ Sbjct: 175 LSKWPRILAYLERNQARPAVQAAMK 199 >3UBL-A nrPDB Length = 242 Score = 71.5 bits (174), Expect = 3e-13, Method: Composition-based stats. Identities = 37/192 (19%), Positives = 80/192 (41%), Gaps = 16/192 (8%) Query: 4 KPKLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQVPMVEIDGM 63 KLH + + ++ + G+E+E+ I +++ L+ ++P++E+DG Sbjct: 3 MIKLHGASISNYVNKVKLGILEKGLEYEQIRIAPSQEEDFLKIS---PMGKIPVLEMDGK 59 Query: 64 KLVQTRAILNYIASKY----NLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDA 119 + ++ AIL ++ + + L +D E A + + + ++ + Sbjct: 60 FIFESGAILEFLDTIFPQTPKLIPEDPWEAARVREISTIIETYLDIPARRIYLPAAKVSP 119 Query: 120 KIALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRAD---ISLVELLYYVEELDSSLIS 176 +I T + A ++V++ Y+ GN + AD + + +L EEL + Sbjct: 120 EIVEEVHSTLVKGIKALQRVVRFS--PYIAGNVFTLADCSGFAHLSVLD--EELRPFYPN 175 Query: 177 NFP--LLKALKT 186 N P LL K Sbjct: 176 NHPLDLLNGWKE 187 >3LFL-A nrPDB Length = 240 Score = 69.5 bits (169), Expect = 1e-12, Method: Composition-based stats. Identities = 39/190 (20%), Positives = 70/190 (36%), Gaps = 16/190 (8%) Query: 16 MEPIRWLLAAAGVEFEEKFIG--SAEDLGKLRNDGSLMFQQVPMVEID-GMKLVQTRAIL 72 E R +L A G+ E I + + +N F VP++E G + ++ Sbjct: 35 AERTRLVLKAKGIRHEVININLKNKPEWFFKKN----PFGLVPVLENSQGQLIYESAITC 90 Query: 73 NYIASKY---NLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAKIALIKEKTK 129 Y+ Y L D E+A M E +++ L+ + A +KE+ + Sbjct: 91 EYLDEAYPGKKLLPDDPYEKACQKMILEL---FSKVPSLVGSFIRSQNKEDYAGLKEEFR 147 Query: 130 SRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDS-SLISNFPLLKALKTRI 188 + +VL + + GN +S D + +E + + + P LK + Sbjct: 148 KEFTKL--EVLTNKKTTFFGGNSISMIDYLIWPWFERLEAMKLNECVDHTPKLKLWMAAM 205 Query: 189 SNLPTVKKFL 198 PTV L Sbjct: 206 KEDPTVSALL 215 >2PMT-A nrPDB Length = 203 Score = 68.4 bits (166), Expect = 3e-12, Method: Composition-based stats. Identities = 45/201 (22%), Positives = 85/201 (42%), Gaps = 23/201 (11%) Query: 6 KLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMF------QQVPMVE 59 KL+Y G + P +L G++F + I DL + + F QVP+++ Sbjct: 2 KLYYTPGSCSLSP-HIVLRETGLDFSIERI----DLRTKKTESGKDFLAINPKGQVPVLQ 56 Query: 60 ID-GMKLVQTRAILNYIAS---KYNLY--GKDIKERALIDMYTEGMADLNEMILLLPLCR 113 +D G L + AI+ Y+A NL K ++ I+ +++++ PL Sbjct: 57 LDNGDILTEGVAIVQYLADLKPDRNLIAPPKALERYHQIEWLNFLASEVHKGYS--PLFS 114 Query: 114 PEEKDAKIALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSS 173 + ++ + ++K K KS++ VL Q + G+ + AD L L + Sbjct: 115 SDTPESYLPVVKNKLKSKFV-YINDVLSK--QKCVCGDHFTVADAYLF-TLSQWAPHVAL 170 Query: 174 LISNFPLLKALKTRISNLPTV 194 +++ L+ RI+ P V Sbjct: 171 DLTDLSHLQDYLARIAQRPNV 191 >3IBH-A nrPDB Length = 233 Score = 67.6 bits (164), Expect = 4e-12, Method: Composition-based stats. Identities = 38/164 (23%), Positives = 70/164 (42%), Gaps = 15/164 (9%) Query: 53 QQVPMVE-IDGMKLVQTRAILNYIASKYN---LYGKDIKERALIDMYTE-GMADLNEMIL 107 VP++E DG + + AI YI + L GK E+ +I M + +L + + Sbjct: 70 GTVPVLELDDGTLIAECTAITEYIDALDGTPTLTGKTPLEKGVIHMMNKRAELELLDPVS 129 Query: 108 LL-----PLCRPEEKDAKIALIKEKTKSRYFP---AFEKVLQSHGQDYLVGNKLSRADIS 159 + P PE + + + + + F+ VL+ + Y+ G+ S ADI+ Sbjct: 130 VYFHHATPGLGPEVELYQNKEWGLRQRDKALHGMHYFDTVLRE--RPYVAGDSFSMADIT 187 Query: 160 LVELLYYVEELDSSLISNFPLLKALKTRISNLPTVKKFLQPGSP 203 ++ L + + + L+A R+ P+VKK L+ S Sbjct: 188 VIAGLIFAAIVKLQVPEECEALRAWYKRMQQRPSVKKLLEIRSK 231 >4PXO-A nrPDB Length = 238 Score = 67.6 bits (164), Expect = 4e-12, Method: Composition-based stats. Identities = 40/212 (18%), Positives = 68/212 (32%), Gaps = 18/212 (8%) Query: 9 YFNGRGRME-PIRWLLAAAGVEFEEKFIG-SAEDLGKLRNDGSLMFQQVPMVEI-DGMKL 65 Y N R +R L G+ +EE F+ A D K VP + DG L Sbjct: 27 YGNWRSAAAFRVRIALNLKGIAYEEVFLDLDAGDQHKPDFLAINPQGAVPALFDGDGPPL 86 Query: 66 VQTRAILNYIASKYNLYGKDIKE-------RALIDMYTEGMADLN-EMILLLPLCRPEEK 117 Q+ AIL+Y+ +E R+L + L + + Sbjct: 87 TQSLAILDYLEETRTGVPLLPEEPRARARARSLAQVVACDTHPLYVPRVRTFLMENYGLP 146 Query: 118 DAKIALIKEKTKSRYFPAFEKVLQSHGQD--YLVGNKLSRADISLVELLYYVEELDSSLI 175 ++ E L + + G+ +S AD+ L+ L Sbjct: 147 RERMLEFLRNAFITGLKTLETRLSNEAGTGRFCQGDAVSHADLCLISLWVGTGIFGID-T 205 Query: 176 SNFPLLKALKTRISNLPTVKKFLQPGSPRKPP 207 + +P +K + + L V + P + P Sbjct: 206 AAYPTVKRISEEVLALDAVAR----AHPLRQP 233 >2GDR-A nrPDB Length = 202 Score = 65.7 bits (159), Expect = 1e-11, Method: Composition-based stats. Identities = 47/206 (22%), Positives = 86/206 (41%), Gaps = 23/206 (11%) Query: 6 KLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMF------QQVPMVE 59 KL+Y G + P L AG+ FE + DL + + VP ++ Sbjct: 2 KLYYSPGACSLSP-HIALREAGLNFELVQV----DLASKKTASGQDYLEVNPAGYVPCLQ 56 Query: 60 -IDGMKLVQTRAILNYIASKY---NLYGKD-IKERALIDMYTEGMA-DLNEMILLLPLCR 113 DG L + AI+ Y+A + L + ER + + ++ +L++ PL Sbjct: 57 LDDGRTLTEGPAIVQYVADQVPGKQLAPANGSFERYHLQQWLNFISSELHKSFS--PLFN 114 Query: 114 PEEKDAKIALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSS 173 P D ++ + + L+ YL+G++LS ADI L +L + ++ Sbjct: 115 PASSDE-WKNAVRQSLNTRLGQVARQLE--HAPYLLGDQLSVADIYLFVVLGWSAYVNID 171 Query: 174 LISNFPLLKALKTRISNLPTVKKFLQ 199 +S +P L+A + R+ V+ L+ Sbjct: 172 -LSPWPSLQAFQGRVGGREAVQSALR 196 >4MDC-A nrPDB Length = 252 Score = 65.3 bits (158), Expect = 2e-11, Method: Composition-based stats. Identities = 39/235 (16%), Positives = 79/235 (33%), Gaps = 33/235 (14%) Query: 3 GKPKLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSL-MFQQVPMVEID 61 P L++ +R +L+ G + E + + R+ +L +P+ D Sbjct: 22 SMPTLYHHPMSPASRFVRLILSEYGYQTE---LSEEQPWENRRDFLTLNPAGTLPVYVDD 78 Query: 62 GMK-----------LVQTRAILNYIASKYNLYGKDIKERALI---------DMYTEGMAD 101 M+ L +T I+ L +D +RA I M + Sbjct: 79 SMRALCGATIISEYLDETSGIMK---RDRRLLAEDPFQRAEIRRLTEWFLQKMEADVTRP 135 Query: 102 LNEMILLLPLCRPEE----KDAKIALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRAD 157 L + P++ D+KI ++ + S + +L G+++S D Sbjct: 136 LVRERIFKLQMTPDQGGGAPDSKILRTSRSNIRQHMKYLSWLAGS--RPWLAGDRISYGD 193 Query: 158 ISLVELLYYVEELDSSLISNFPLLKALKTRISNLPTVKKFLQPGSPRKPPADAKA 212 ++ + ++ L S+ P K R+ + P+ + L P A Sbjct: 194 LAAAAAISVLDYLGEIDWSDAPTAKEWYQRLKSRPSFRPLLAERVRGVTPVSHYA 248 >1F2E-A nrPDB Length = 201 Score = 64.9 bits (157), Expect = 2e-11, Method: Composition-based stats. Identities = 48/191 (25%), Positives = 78/191 (40%), Gaps = 22/191 (11%) Query: 21 WLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMF------QQVPMVEID-GMKLVQTRAILN 73 L G +FE + DL + + F +VP + +D G L + AIL Sbjct: 16 IALRETGADFEAVKV----DLAVRKTEAGEDFLTVNPSGKVPALTLDSGETLTENPAILL 71 Query: 74 YIASKYNLYGKDIKE----RALI-DMYTEGMADLNEMILLLPLCRPEEKDAKIALIKEKT 128 YIA + G E R + + ++ ++ +PL P D A E Sbjct: 72 YIADQNPASGLAPAEGSLDRYRLLSRLSFLGSEFHK--AFVPLFAPATSDEAKAAAAESV 129 Query: 129 KSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLISNFPLLKALKTRI 188 K+ + A +K L G+D+ GN S ADI L +L + + ++ +P L A +I Sbjct: 130 KN-HLAALDKELA--GRDHYAGNAFSVADIYLYVMLGWPAYVGID-MAAYPALGAYAGKI 185 Query: 189 SNLPTVKKFLQ 199 + P V L+ Sbjct: 186 AQRPAVGAALK 196 >4J2F-A nrPDB Length = 223 Score = 64.9 bits (157), Expect = 3e-11, Method: Composition-based stats. Identities = 42/209 (20%), Positives = 72/209 (34%), Gaps = 22/209 (10%) Query: 1 MAGKPKLH-YFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQ---QVP 56 MA KLH + I W L G+ +E EDL ++P Sbjct: 1 MAEVLKLHGAWPSPFSCRVI-WALKLKGIPYE----YVEEDLFNKSPLLLQYNPVHKKIP 55 Query: 57 MVEIDGMKLVQTRAILNYIASKYN---LYGKDIKERALIDMYTEGMADLNEMILLLPLCR 113 ++ G + ++ IL Y+ + L D ERA+ + + + D I + + Sbjct: 56 VLVHGGKPICESTIILEYLDETWPENPLLPSDPHERAVARFWVKFIEDKGTAIWNIFRTK 115 Query: 114 PEEKDAKIALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADI------SLVELLYYV 167 EE + + E K+ E + Y G+K+ DI + ++ V Sbjct: 116 GEELEKAVKNCLEVLKTIE----EHAMGVSDDKYFGGDKIGIVDIAFCGIAHWLGVIEEV 171 Query: 168 EELDSSLISNFPLLKALKTRISNLPTVKK 196 + FP L A P +K+ Sbjct: 172 AGVKVLESQKFPRLHAWTENFKEAPIIKE 200 >3TOT-A nrPDB Length = 226 Score = 64.1 bits (155), Expect = 5e-11, Method: Composition-based stats. Identities = 36/187 (19%), Positives = 68/187 (36%), Gaps = 16/187 (8%) Query: 19 IRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQVPMVE-IDGMKLVQTRAILNYIAS 77 +R +LA ++++ F+ + +VP + DG L +R I Y A Sbjct: 17 VRVVLAEKKIDYQ--FVLEDVWNADTQIHQFNPLGKVPCLVMDDGGALFDSRVIAEY-AD 73 Query: 78 KYN----LYGKDIKERALIDMYTEGMADLNEMILLLPLCR----PEEKDAKIALIKEKTK 129 + L +ER + + L + + L + + PE++ + Sbjct: 74 TLSPVARLIPPSGRERVEVRCWEALADGLLDAAVALRVEQTQRTPEQRSESWITRQHHKI 133 Query: 130 SRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSL--ISNFPLLKALKTR 187 A + L + + GN L+ ADI++ L Y++ + L A TR Sbjct: 134 DEALKAMSRGLAD--RTWCNGNHLTLADIAVGCALAYLDFRQPQVDWREQHANLAAFYTR 191 Query: 188 ISNLPTV 194 I P+ Sbjct: 192 IEKRPSF 198 >3LG6-A nrPDB Length = 235 Score = 63.7 bits (154), Expect = 6e-11, Method: Composition-based stats. Identities = 35/209 (16%), Positives = 73/209 (34%), Gaps = 22/209 (10%) Query: 8 HYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSL-MFQQVPMVEID----- 61 YF +R + + + + SL VP++ + Sbjct: 14 GYFRSSCSGR-LRIAFHLKSIPYTRHPVNLLKGEQHSDTYKSLNPTNTVPLLVVSNINNT 72 Query: 62 ------GMKLVQTRAILNYIASK-----YNLYG--KDIKERALIDMYTEGMA-DLNEMIL 107 + Q+ A L Y+ L + RA + +A D+ + Sbjct: 73 VSPSSASFSIGQSLAALEYLEEALPTNARPLLPPISNPVARAHVRTICNIIACDVQPVTN 132 Query: 108 LLPLCRPEEKDAKIALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYV 167 L + + D + ++ F A EK+L+ + VG++++ AD+ LV ++ Sbjct: 133 LKIQKKVKALDGDPTVWSRDLATQGFGAVEKLLELSAGRFCVGDEITLADVCLVPAVWAA 192 Query: 168 EELDSSLISNFPLLKALKTRISNLPTVKK 196 E + ++ FP+ K + + V+K Sbjct: 193 ERV-GMDLARFPITKRVFEEMLKEEAVQK 220 >3NIV-A nrPDB Length = 222 Score = 63.0 bits (152), Expect = 9e-11, Method: Composition-based stats. Identities = 40/205 (19%), Positives = 82/205 (40%), Gaps = 20/205 (9%) Query: 6 KLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQ------VPMVE 59 L+ + +R L + +E+ + + G+ SL + Q VP ++ Sbjct: 4 ILYDYFRSTACYRVRIALNLKKIAYEKIEVHLVNNGGE---QHSLQYHQINPQELVPSLD 60 Query: 60 IDGMKLVQTRAILNYIASKY---NLYGKDI-KERALIDMYTEGMADLNEMILLLPLCRPE 115 I+G L Q+ AI++Y+ + L KD + L M D++ + L L R + Sbjct: 61 INGQILSQSMAIIDYLEEIHPEMPLLPKDPFMKATLKSMALIVACDMHPLNNLRVLNRLK 120 Query: 116 EK----DAKIALIKEKTKSRYFPAFEKVLQ--SHGQDYLVGNKLSRADISLVELLYYVEE 169 E+ + ++ F AFE+ L + G+++ AD+ L+ +Y Sbjct: 121 EQFNANEEQVLEWYHHWLKTGFDAFEEKLGALERDKPVCFGSEVGLADVCLIPQVYNAHR 180 Query: 170 LDSSLISNFPLLKALKTRISNLPTV 194 ++++P++ + LP Sbjct: 181 FHFD-MASYPIINEINEYCLTLPAF 204 >3PR8-A nrPDB Length = 229 Score = 62.2 bits (150), Expect = 2e-10, Method: Composition-based stats. Identities = 45/223 (20%), Positives = 84/223 (37%), Gaps = 15/223 (6%) Query: 6 KLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQVPMVEIDGMKL 65 KL+ F+ ++ L G+ FEE + L +VP++E + L Sbjct: 4 KLYGFSVSNYYNMVKLALLEKGLTFEEVTFYGGQAPQALEVSPR---GKVPVLETEHGFL 60 Query: 66 VQTRAILNYIASKYN---LYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAKIA 122 +T IL+YI L D +A + + + E+ + Sbjct: 61 SETSVILDYIEQTQGGKALLPADPFGQAKVRELLKEIELYIELPARTCYAESFFGMSVEP 120 Query: 123 LIKEKTKSRYFPAFEKVLQSHGQ--DYLVGNKLSRADISLVELLYYVE-----ELDSSLI 175 LIKEK ++ F L+ +G+ Y+ G +L+ AD+ + L+ + Sbjct: 121 LIKEKARADLLAGFAT-LKRNGRFAPYVAGEQLTLADLMFCFSVDLANAVGKKVLNIDFL 179 Query: 176 SNFPLLKALKTRISNLPTVKKFLQPGSPRKPPADAKALEEARK 218 ++FP KAL + P + + L PA + + ++ Sbjct: 180 ADFPQAKALLQLMGENPHMPRILADKE-ASMPAFMEMIRSGKR 221 >5ELG-A nrPDB Length = 221 Score = 62.2 bits (150), Expect = 2e-10, Method: Composition-based stats. Identities = 36/198 (18%), Positives = 72/198 (36%), Gaps = 27/198 (13%) Query: 21 WLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQVPMVEIDGMKLVQTRAILNYIASKYN 80 L + ++ I D + D S +VP+++ID + + I+ + KY Sbjct: 28 LTLEEKSLTYKIHLINL-SDKPQWFLDIS-PQGKVPVLKIDDKWVTDSDVIVGILEEKYP 85 Query: 81 LYG-KDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAKIALIKEKTKSRYFPAFEKV 139 K E A + +++ + ++ AL+ E A E Sbjct: 86 DPPLKTPAEFASV------GSNIFGTFGTFLKSKDSNDGSEHALLVE------LEALENH 133 Query: 140 LQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLISNFPLLKALKTRISNLPTVKKFLQ 199 L+SH ++ G ++S D+SL LY+++ S + + P V +++ Sbjct: 134 LKSHDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKS--------WSVPESFPHVHNYMK 185 Query: 200 P----GSPRKPPADAKAL 213 S K + K + Sbjct: 186 TLFSLDSFEKTKTEEKYV 203 >3C8E-A nrPDB Length = 288 Score = 60.7 bits (146), Expect = 5e-10, Method: Composition-based stats. Identities = 28/195 (14%), Positives = 66/195 (33%), Gaps = 25/195 (12%) Query: 21 WLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQ--VPMVEIDGM----KLVQTRAILNY 74 L G E+ + ++ D + + + +P + ++ ++ +IL Y Sbjct: 66 LALGVTGAEY-DAWLIRIGDGDQFSSGFVEVNPNSKIPALRDHTHNPPIRVFESGSILLY 124 Query: 75 IASKYN-LYGKDIKERALID---MYTEGMADLNEMILLLPLCRPEEKDAKIALIKEKTKS 130 +A K+ +D+ +R + +G A K Sbjct: 125 LAEKFGYFLPQDLAKRTETMNWLFWLQGAAPFLGGGFGHFYHYAPVKIEYAINRFTMEAK 184 Query: 131 RYFPAFEKVLQSHGQDYLVGNKLSRADISLVE---------LLYYVEELDSSLISNFPLL 181 R +K L H ++ G++ + AD+++ + E LD+ ++ + Sbjct: 185 RLLDVLDKQLAQH--KFVAGDEYTIADMAIWPWFGNVVLGGVYDAAEFLDAG---SYKHV 239 Query: 182 KALKTRISNLPTVKK 196 + + P VK+ Sbjct: 240 QRWAKEVGERPAVKR 254 >5LOL-A nrPDB Length = 215 Score = 60.7 bits (146), Expect = 5e-10, Method: Composition-based stats. Identities = 32/157 (20%), Positives = 57/157 (36%), Gaps = 21/157 (13%) Query: 17 EPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQVPMVEIDGMKLVQTRAILNYIA 76 + + L + ++ I D + D S +VP+V++DG + + I+ + Sbjct: 26 QRVLLTLEEKKLPYKTHLINV-SDKPQWFLDIS-PEGKVPVVKLDGKWVADSDVIVGLLE 83 Query: 77 SKY---NLYGKDIKERALI-DMYTEGMADLNEMILLLPLCRPEEKDAKIALIKEKTKSRY 132 KY +L K E A + K EK Sbjct: 84 EKYPEPSL--KTPPEFASVGSKIFGAFVTFL-------------KSKDANDGSEKALVDE 128 Query: 133 FPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEE 169 A E L++H ++ G K++ D+SL LY++E Sbjct: 129 LEALENHLKTHSGPFVAGEKITAVDLSLAPKLYHLEV 165 >4MK3-A nrPDB Length = 226 Score = 59.9 bits (144), Expect = 8e-10, Method: Composition-based stats. Identities = 34/197 (17%), Positives = 64/197 (32%), Gaps = 16/197 (8%) Query: 6 KLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQVPMVE-IDGMK 64 KL+ +R +LA +++E I +VP + DG Sbjct: 24 KLYASQTSPYARKVRVVLAEKKIDYE--MIEENVWSPDTTIGRFNPLGKVPCLVMEDGGA 81 Query: 65 LVQTRAILNYIASKYN----LYGKDIKERALIDMYTEGMADLNEMILLLPLC----RPEE 116 + +R I Y A + L + +ER + + L + LL L + E Sbjct: 82 VFDSRVIAEY-ADTLSPVSRLIPQGSRERLEVRCWEALADGLLDAALLARLEVTQRKESE 140 Query: 117 KDAKIALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLI- 175 + + A L + + G + AD+++ L Y++ + Sbjct: 141 RSESWVQRQRSKIDAALTAMSTGLAD--KTWCTGTHYTLADVAVGCALAYLDFRFPDIAW 198 Query: 176 -SNFPLLKALKTRISNL 191 P L A + +I Sbjct: 199 RDRHPNLVAFQEKIEKR 215 >2JL4-A nrPDB Length = 213 Score = 59.9 bits (144), Expect = 9e-10, Method: Composition-based stats. Identities = 38/192 (19%), Positives = 69/192 (35%), Gaps = 14/192 (7%) Query: 4 KPKLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQ--VPMVEID 61 K KL+ F G +R L GV +E + ++ L++ + Q VP ++ Sbjct: 1 KMKLYNFWRSGTSHRLRIALNLKGVPYEYLAVHLGKE-EHLKDAFKALNPQQLVPALDTG 59 Query: 62 GMKLVQTRAILNYIASKY---NLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKD 118 L+Q+ AI+ ++ +Y L D R + + I + K Sbjct: 60 AQVLIQSPAIIEWLEEQYPTPALLPADADGRQRVRALAAIVGCDIHPINNRRILEYLRKT 119 Query: 119 AKIALIKEKT-----KSRYFPAFEKVLQSHGQ--DYLVGNKLSRADISLVELLYYVEELD 171 S F A+E +L + Y G+ + AD LV + Sbjct: 120 FGADEAAINAWCGTWISAGFDAYEALLAVDPKRGRYSFGDTPTLADCYLVPQVESARRFQ 179 Query: 172 SSLISNFPLLKA 183 ++ +PL++A Sbjct: 180 VD-LTPYPLIRA 190 >4QQ7-A nrPDB Length = 207 Score = 59.5 bits (143), Expect = 1e-09, Method: Composition-based stats. Identities = 34/192 (17%), Positives = 76/192 (39%), Gaps = 14/192 (7%) Query: 17 EPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSL-MFQQVPMVEIDGMKLVQTRAILNYI 75 + R +L G++FE I + K + + + QVP++ + L ++ I YI Sbjct: 18 QRCRLVLFEKGMDFE---IRDVDLFNKPEDISVMNPYGQVPILVERDLILYESNIINEYI 74 Query: 76 ASKY---NLYGKDIKERALIDMY-TEGMADLNEMILLLPLCRPEEKDAKIALIKEKTKSR 131 ++ L D +RA ++ +L + L + + + + + R Sbjct: 75 DERFPHPQLMPADPVQRARARLFLLNFEKELFVHVSTLENEKGKAAEKNHEKARLAIRDR 134 Query: 132 YFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLISNFPLLKALKTRISNL 191 +++ Y++G + S D+++ LL+ ++ L N L RI + Sbjct: 135 LTQLAPIFVKN---KYMLGEEFSMLDVAIAPLLWRLDHYGIELSKNAAPLMKYAERIFSR 191 Query: 192 PTVKKFLQPGSP 203 P +++ +P Sbjct: 192 P---AYIEALTP 200 >4CHS-A nrPDB Length = 219 Score = 59.1 bits (142), Expect = 1e-09, Method: Composition-based stats. Identities = 32/186 (17%), Positives = 66/186 (35%), Gaps = 15/186 (8%) Query: 19 IRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQVPMVEIDGMKLVQTRAILNYIASK 78 +R LA G+E+E K L + +++P++ +G + ++ + YI Sbjct: 19 VRIALAEKGIEYEYKEEDLRNKSPLLLQMNPVH-KKIPVLIHNGKPISESLIAVQYIEEV 77 Query: 79 YN----LYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAKIALIKEKTKSRYFP 134 +N L D +RA + + + + E+ K Sbjct: 78 WNDRNPLLPSDPYQRAQARFWADYVDIKIHDLGKKIWTSKGEEKEAAK----KEFIEALK 133 Query: 135 AFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDS----SLISNFPLLKALKTRISN 190 E+ L + Y G+ + DI+LV + + ++ ++ + P A R Sbjct: 134 LLEEQLGD--KTYFGGDNIGFVDIALVPFYTWFKVYETFGSLNIENECPRFVAWAKRCLQ 191 Query: 191 LPTVKK 196 +V K Sbjct: 192 KESVAK 197 >5NR1-A nrPDB Length = 228 Score = 58.0 bits (139), Expect = 3e-09, Method: Composition-based stats. Identities = 43/226 (19%), Positives = 78/226 (34%), Gaps = 26/226 (11%) Query: 1 MAGKPKLHYFNGRGRMEPIRWLLAAAGVEFEE---KFIGSAEDLGKLRNDGSLMFQQVPM 57 M+ + LH+F +R L + F E ++ + L + P+ Sbjct: 1 MSVERTLHHFPLDPASRQVRLALGEKRLPFVEMQVRYWEMPPEFTSLNPS-GMP----PV 55 Query: 58 VEIDGMK----LVQTRAILNYIASKYN---LYGKDIKERALID---MYTEGMAD------ 101 + + + +TRAIL +I L G+D ERA + + D Sbjct: 56 LVETKHQRNLVICETRAILEHIEETETEPPLLGRDPAERAEARRLLQWFDRKFDNEVNGF 115 Query: 102 LNEMILLLPLCRPEEKDAKIALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLV 161 L + L R D + + E +LQ+ +D+L G ++S AD + Sbjct: 116 LLHEKMEKRLLRMGAPDLAALRQGREALRMHLGYIESLLQT--RDWLAGRRMSLADFAAA 173 Query: 162 ELLYYVEELDSSLISNFPLLKALKTRISNLPTVKKFLQPGSPRKPP 207 L ++ +F K ++ + P + L P P Sbjct: 174 AHLSVIDYFGDVPWKDFQAAKTWYMKLKSRPCFRPILADRWPGLAP 219 >5F8B-A nrPDB Length = 244 Score = 58.0 bits (139), Expect = 3e-09, Method: Composition-based stats. Identities = 39/169 (23%), Positives = 64/169 (37%), Gaps = 27/169 (15%) Query: 6 KLHYFNG-RGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQVPMVE-IDGM 63 L+ F G + R I+ + A G++ + + D + +VP + D Sbjct: 5 TLYTFPGDQCRTIAIKAVAKANGLDLDIRETPRTPDHLSISK-----LGKVPAFQGADSF 59 Query: 64 KLVQTRAILNYIA---SKYNLYGKDIKERALI---------DMYTEGMADLNEMILLLPL 111 KL + AI YI + L GKD KE A I ++ L + ++P Sbjct: 60 KLFECMAIALYITSQNEQTTLLGKDKKEYAEIIKWMSFFNTEIVILMTQQLLPQLGVIPY 119 Query: 112 CRPEEKDAKIALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISL 160 R + R E+ LQ + +LVG++LS AD+ Sbjct: 120 DRDQ------VEFFANMTQRSVDVVEEYLQD--RTFLVGDQLSLADLFC 160 >3GX0-A nrPDB Length = 215 Score = 57.2 bits (137), Expect = 5e-09, Method: Composition-based stats. Identities = 37/199 (18%), Positives = 69/199 (34%), Gaps = 19/199 (9%) Query: 9 YFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQ--VPMVEI----DG 62 YF I L A +++ + + G+ R + + +P + DG Sbjct: 5 YFAPTPNGHKITLFLEEAELDYRLIKVDLGK-GGQFRPEFLRISPNNKIPAIVDHSPADG 63 Query: 63 ---MKLVQTRAILNYIASKYNLYGKDI-KERALIDMY----TEGMADLNEMILLLPLCRP 114 + L ++ AIL Y+A K L+ +ERA + G+ + P Sbjct: 64 GEPLSLFESGAILLYLAEKTGLFLSHETRERAATLQWLFWQVGGLGPMLGQNHHFNHAAP 123 Query: 115 EEKDAKIALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSL 174 + + R + K L++ +L G S ADI+ + Sbjct: 124 -QTIPYAIERYQVETQRLYHVLNKRLENS--PWLGGENYSIADIACWPWVNAWTR-QRID 179 Query: 175 ISNFPLLKALKTRISNLPT 193 ++ +P +K RI + P Sbjct: 180 LAMYPAVKNWHERIRSRPA 198 >2PVQ-A nrPDB Length = 201 Score = 57.2 bits (137), Expect = 6e-09, Method: Composition-based stats. Identities = 44/209 (21%), Positives = 76/209 (36%), Gaps = 29/209 (13%) Query: 6 KLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMF------QQVPMVE 59 KL+Y +L+ AG+ +E + + DL + + VP +E Sbjct: 2 KLYY-KVGAASLAPHIILSEAGLPYELEAV----DLKAKKTADGGDYFAVNPRGAVPALE 56 Query: 60 ID-GMKLVQTRAILNYIASKYNL------YGKDIKERALIDMYTEGMADLNEMI--LLLP 110 + G + Q AIL YI ++ YG ERA + +DL+ L P Sbjct: 57 VKPGTVITQNAAILQYIGDHSDVAAFKPAYGS--IERARLQEALGFCSDLHAAFSGLFAP 114 Query: 111 LCRPEEKDAKIALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEEL 170 E + IA I + E +L +L G+ ++ D ++ Sbjct: 115 NLSEEARAGVIANINRR-----LGQLEAMLSDKNAYWL-GDDFTQPDAYA-SVIIGWGVG 167 Query: 171 DSSLISNFPLLKALKTRISNLPTVKKFLQ 199 +S +P L+ R+ P V+K + Sbjct: 168 QKLDLSAYPKALKLRERVLARPNVQKAFK 196 >2VO4-A nrPDB Length = 219 Score = 56.0 bits (134), Expect = 1e-08, Method: Composition-based stats. Identities = 33/186 (17%), Positives = 66/186 (35%), Gaps = 15/186 (8%) Query: 19 IRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQVPMVEIDGMKLVQTRAILNYIASK 78 +R LA G+++E K L + +++P++ +G + ++ + YI Sbjct: 19 VRIALAEKGIKYEYKEEDLRNKSPLLLQMNPVH-KKIPVLIHNGKPICESLIAVQYIEEV 77 Query: 79 YN----LYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAKIALIKEKTKSRYFP 134 +N L D +RA + + + + E+ K Sbjct: 78 WNDRNPLLPSDPYQRAQTRFWADYVDKKIYDLGRKIWTSKGEEKEAAK----KEFIEALK 133 Query: 135 AFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDS----SLISNFPLLKALKTRISN 190 E+ L + Y G+ L DI+LV + + ++ ++ S P A R Sbjct: 134 LLEEQLGD--KTYFGGDNLGFVDIALVPFYTWFKAYETFGTLNIESECPKFIAWAKRCLQ 191 Query: 191 LPTVKK 196 +V K Sbjct: 192 KESVAK 197 >4IKH-A nrPDB Length = 244 Score = 54.5 bits (130), Expect = 3e-08, Method: Composition-based stats. Identities = 33/192 (17%), Positives = 69/192 (35%), Gaps = 21/192 (10%) Query: 21 WLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQ--VPMVEI----DG--MKLVQTRAIL 72 +L G+ +E + S E ++ + + +P + + L ++ AIL Sbjct: 38 IMLEEIGLPYEAHRV-SFETQDQMTPEFLSVSPNNKIPAILDPHGPGDQPLALFESGAIL 96 Query: 73 NYIASKYN-LYGKDIKERALIDMYT----EGMADLNEMILLLPLCRPEE-KDAKIALIKE 126 Y+A K L ++ R + G+ + + E +D + Sbjct: 97 IYLADKSGQLLAQESAARYETIQWLMFQMGGIGPMFGQVGFFNKFAGREYEDKRPLERYV 156 Query: 127 KTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDS----SLISNFPLLK 182 R +K L G+++++G + + ADI+ + + I NFP +K Sbjct: 157 NEAKRLLGVLDKHLG--GREWIMGERYTIADIATFPWIRNLIGFYEAGELVGIDNFPEVK 214 Query: 183 ALKTRISNLPTV 194 + + P V Sbjct: 215 RVLAKFVARPAV 226 >5J5N-A nrPDB Length = 231 Score = 52.6 bits (125), Expect = 1e-07, Method: Composition-based stats. Identities = 34/191 (17%), Positives = 66/191 (34%), Gaps = 19/191 (9%) Query: 19 IRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLM--FQQVPMVEIDGMKLVQTRAILNYIA 76 +R LA GV++E + K + +Q+P++ +G + ++ I+ YI Sbjct: 31 VRLALAEKGVKYE---YSEEDLWNKSALLLQMNPVNKQIPVLVHNGKPVCESLIIVQYID 87 Query: 77 SKYN----LYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAKIALIKEKTKSRY 132 + L D +RA + + + + + E+ + Sbjct: 88 EVWKDSAPLLPSDPYQRAQSRFWADFVDKKIYDLGRKIWTKKGEEQEAAKKDFIDS---- 143 Query: 133 FPAFEKVLQSHGQDYLVGNKLSRADISLVE----LLYYVEELDSSLISNFPLLKALKTRI 188 E L + Y G + DI+LV Y + ++ + P + A R Sbjct: 144 LKLMEGELGD--KPYFGGETIGYVDIALVPFYSWFYAYETIGNFNIEAECPKMIAYCKRC 201 Query: 189 SNLPTVKKFLQ 199 TV K L+ Sbjct: 202 LQKETVSKALE 212 >5ECL-B nrPDB Length = 223 Score = 51.8 bits (123), Expect = 2e-07, Method: Composition-based stats. Identities = 39/205 (19%), Positives = 69/205 (33%), Gaps = 17/205 (8%) Query: 1 MAGKPKLH-YFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQVPMVE 59 MA P L Y+ M R L GVEFE + L + + +++P++ Sbjct: 7 MANLPILLDYWPSMFGMRA-RVALREKGVEFE-YREEDFSNKSPLLLQSNPIHKKIPVLV 64 Query: 60 IDGMKLVQTRAILNYI----ASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPE 115 +G + ++ ++ Y+ K + D RA + + + + Sbjct: 65 HNGKPVCESLNVVQYVDEAWPEKNPFFPSDPYGRAQARFWADFVDKKFTDAQFKVWGKKG 124 Query: 116 EKDAKIALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDS--- 172 E+ K E L + Y G+ DISL+ + + + Sbjct: 125 EEQEAGK----KEFIEAVKILESELGD--KPYFGGDSFGYVDISLITFSSWFQAYEKFGN 178 Query: 173 -SLISNFPLLKALKTRISNLPTVKK 196 S+ S P L A R +V K Sbjct: 179 FSIESESPKLIAWAKRCMEKESVSK 203 >3PPU-A nrPDB Length = 352 Score = 51.8 bits (123), Expect = 2e-07, Method: Composition-based stats. Identities = 29/124 (23%), Positives = 55/124 (44%), Gaps = 14/124 (11%) Query: 78 KYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAKIALIKEKTKSRYFPAFE 137 K +LY + + RA ID + + D + +K + A+I E Sbjct: 195 KLDLYPESL--RAKIDEVNDWVYDTVNNGVYKSGFASTQKAYEAAVIP---LFESLDRLE 249 Query: 138 KVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLISNFP-LLKALKTRISNLPTVKK 196 K+L+ GQDYL+G +L+ ADI L + D +++F L+ ++ P + + Sbjct: 250 KMLE--GQDYLIGGQLTEADIRLFVTIV---RFDPVYVTHFKCNLRTIRD---GYPNLHR 301 Query: 197 FLQP 200 +++ Sbjct: 302 WMRK 305 >6JWK-A nrPDB Length = 222 Score = 51.0 bits (121), Expect = 4e-07, Method: Composition-based stats. Identities = 40/213 (18%), Positives = 77/213 (36%), Gaps = 18/213 (8%) Query: 7 LHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSL--MFQQVPMVEI-DGM 63 L+ F +R LA G++++ + +LR +P + DG Sbjct: 3 LYSFFNSSTSYRVRIALALKGLDYQVVPVNLR-QGEQLRPADRQRNPMGALPTLVDADGR 61 Query: 64 KLVQTRAILNYIAS---KYNLYGKDIKERALIDMYTEGMA-DLNEMILLLPLCRPEEKDA 119 + Q+ AI++Y+ + + L D RA +A D++ + + L + Sbjct: 62 RFSQSLAIIDYLDAVQPEPRLIPLDPLHRAQALELALLVACDIHPLNNVRVLKYLTQVLG 121 Query: 120 KIALIKEK----TKSRYFPAFEKVLQSHGQ-DYLVGNKLSRADISLVELLYYVEELDSSL 174 A +++ + A E +L H + + G + LV L + Sbjct: 122 IDAEDRQRWYAHWVAEGLAAAETLLNRHRRGAFFAGAAAGIVECCLVPQLANARRMGCD- 180 Query: 175 ISNFPLLKALKTRISNLPTVKKFLQPGSPRKPP 207 ++ +P L L+ R L Q SP + P Sbjct: 181 LAPYPALLELEGRCLALEA----FQRASPERQP 209 >5N9U-A nrPDB Length = 218 Score = 51.0 bits (121), Expect = 4e-07, Method: Composition-based stats. Identities = 31/190 (16%), Positives = 67/190 (35%), Gaps = 27/190 (14%) Query: 16 MEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQVPMVEIDGMKLVQTRAILNYI 75 + + L + ++ I D + + S +VP+V+ID + + I+ + Sbjct: 23 CQRVLLSLEEKKIPYKSHLINL-GDKPQWFLEIS-PEGKVPVVKIDDKWVADSDVIVGIL 80 Query: 76 ASKYNLYGK----DIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAKIALIKEKTKSR 131 K + E A + + + + + + AL++E Sbjct: 81 EEK---NPEPPLATPPEFASV------GSKIFPSFVKFLKSKDPNDGTEQALLEE----- 126 Query: 132 YFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLI-----SNFPLLKALKT 186 A + L+ HG ++ G K++ D+SL LY++E N + Sbjct: 127 -LKALDGHLKVHG-PFIAGEKITAVDLSLAPKLYHLEVALGHFKNWPIPDNLTHVLNYIK 184 Query: 187 RISNLPTVKK 196 + + + KK Sbjct: 185 LLFSRESFKK 194 >4PQI-A nrPDB Length = 241 Score = 48.3 bits (114), Expect = 3e-06, Method: Composition-based stats. Identities = 25/181 (13%), Positives = 58/181 (32%), Gaps = 21/181 (11%) Query: 25 AAGVEFEEKFIGSA-EDLGKLRNDGSLMFQQVPMVEIDGMKLVQTRAILNYIASKY---N 80 G++ E K + ++ + +VP +E +G ++ ++ Y+ S + + Sbjct: 53 FKGLQDEIKLVPLILQNRPAWYPEKVYPPNKVPSLEHNGKITGESLDLIKYLESNFEGPS 112 Query: 81 LYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAKIALIKEKTKSRYFPAFEKVL 140 L KD ++ + N + K F E L Sbjct: 113 LLPKDPAKKEFAEELFSYTDKFNGTVYTAF-----------KGDLAKEAGPAFDHLENAL 161 Query: 141 QSH-GQDYLVGNKLSRADISLVE-----LLYYVEELDSSLISNFPLLKALKTRISNLPTV 194 + +G + S DI+ + ++ +E + + L A ++ + Sbjct: 162 HKFDDGPFFLGKEFSLVDIAYIPFVERLNIFLLEVFKYDITAGRQKLAAWIEEVNKIEAY 221 Query: 195 K 195 K Sbjct: 222 K 222 >3RBT-A nrPDB Length = 246 Score = 47.6 bits (112), Expect = 4e-06, Method: Composition-based stats. Identities = 36/205 (17%), Positives = 73/205 (35%), Gaps = 28/205 (13%) Query: 1 MAGKPKLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSA--EDLGKLRNDGSLMFQQVPMV 58 + K +L++ + + +L A +++E + + + +N ++P++ Sbjct: 23 LTDKLRLYHVDMNPYGHRVLLVLEAKRIKYEVYRLDPLRLPEWFRAKNPRL----KIPVL 78 Query: 59 EI----DGMKLVQTRAILNYIASK---YNLYGKDIKERALIDMYTEGMADLNEMILLLPL 111 EI L ++ I +Y+ K + L+ D +A + E +L + L Sbjct: 79 EIPTDQGDRFLFESVVICDYLDEKYTRHTLHSHDPYVKAQDRLLIERFNELIKGSLECFD 138 Query: 112 CRPEEKDAKIALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISL---VELLYYVE 168 +I FEK L + G +Y GN+ D + VE LY + Sbjct: 139 TNFAFGSEQIIQT--------LEIFEKELTNRGTNYFGGNRPGMLDYMVWPWVERLYLLR 190 Query: 169 -ELDSSLISN---FPLLKALKTRIS 189 D + FP ++ Sbjct: 191 CVNDRKFVEKKSLFPNFADWGDQMQ 215 >4BVY-B nrPDB Length = 186 Score = 47.2 bits (111), Expect = 6e-06, Method: Composition-based stats. Identities = 27/157 (17%), Positives = 56/157 (35%), Gaps = 24/157 (15%) Query: 54 QVPMVEI-DGMKLVQTRAILNYIASKYN---LYGKDIKERALIDMYTEGMADLNEMILLL 109 Q+P+++ DG L I ++ + N L G +E+A++ + E Sbjct: 41 QIPVLQTNDGPSLTGLTTIAAHLVKQANKEYLLGSTAEEKAIVQQWLE-----------Y 89 Query: 110 PLCRPEEKDAKIALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELL-YYVE 168 + + + +K L+ + YL G + ADI L L ++ Sbjct: 90 RVTQVDGHSSKND------IHTLLKDLNSYLED--KVYLTGYNFTLADILLYYGLHRFIV 141 Query: 169 ELDSSLISNFPLLKALKTRISNLPTVKKFLQPGSPRK 205 +L + + + I + P +++ L K Sbjct: 142 DLTVQEKEKYLNVSRWFSHIQHYPGIRQHLSSVVFIK 178 >6GC9-A nrPDB Length = 327 Score = 46.8 bits (110), Expect = 8e-06, Method: Composition-based stats. Identities = 26/122 (21%), Positives = 51/122 (41%), Gaps = 14/122 (11%) Query: 80 NLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAKIALIKEKTKSRYFPAFEKV 139 +LY + + R ID E + D + +K + A++ EK+ Sbjct: 168 DLYPEAL--RGEIDGINEWVYDTVNNGVYKSGFATSQKAYEAAVVP---LFESLDRLEKI 222 Query: 140 LQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLISNFP-LLKALKTRISNLPTVKKFL 198 L G+DYLVG++L+ ADI L + D + +F ++ ++ P + ++ Sbjct: 223 L--TGKDYLVGDQLTEADIRLFVTIV---RFDPVYVGHFKCNIRTIRD---GYPAIDLWM 274 Query: 199 QP 200 + Sbjct: 275 RK 276 >1N2A-A nrPDB Length = 201 Score = 45.6 bits (107), Expect = 2e-05, Method: Composition-based stats. Identities = 30/178 (16%), Positives = 67/178 (37%), Gaps = 17/178 (9%) Query: 23 LAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQVPMVEIDGMKLV-QTRAILNYIASKYN- 80 V+ +K + + +D + QVP + +D L+ + AI+ Y+A Sbjct: 25 FTLVSVDLMKKRLENGDDYFAVNPK-----GQVPALLLDDGTLLTEGVAIMQYLADSVPD 79 Query: 81 ---LYGKDIKERALIDMYTEGMA-DLNEMILLLPLCRPEEKDAKIALIKEKTKSRYFPAF 136 L + R + +A +L++ PL RP+ + ++ + + + Sbjct: 80 RQLLAPVNSISRYKTIEWLNYIATELHKGF--TPLFRPDTPEEYKPTVRAQLEKK-LQYV 136 Query: 137 EKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLISNFPLLKALKTRISNLPTV 194 + L+ + ++ G + + AD L +L + + A R++ P V Sbjct: 137 NEALKD--EHWICGQRFTIADAYLFTVL-RWAYAVKLNLEGLEHIAAFMQRMAERPEV 191 >1G6W-A nrPDB Length = 261 Score = 45.3 bits (106), Expect = 2e-05, Method: Composition-based stats. Identities = 33/190 (17%), Positives = 71/190 (37%), Gaps = 45/190 (23%) Query: 54 QVPMVEI---DGMKLVQTRAILNYIASKYN-------LYGKDIKERALIDMY----TEGM 99 +VP + D + + ++ AIL ++ +KY L+ D+ +++ I+ + T G Sbjct: 71 RVPALIDHGMDNLSIWESGAILLHLVNKYYKETGNPLLWSDDLADQSQINAWLFFQTSGH 130 Query: 100 ADLNEMILLLPLCRPEEKDAKIALIKEKTKSRYFPAFEKVLQSHGQD------------- 146 A + L ++ + + ++ + R + E L + Sbjct: 131 APMIGQALHFRYFHSQKIASAVERYTDEVR-RVYGVVEMALAERREALVMELDTENAAAY 189 Query: 147 -----------------YLVGNKLSRADISLVELLYYVEELDSSLISNFPLLKALKTRIS 189 +LVG+KL+ AD++ V V+ + ++ FP + + Sbjct: 190 SAGTTPMSQSRFFDYPVWLVGDKLTIADLAFVPWNNVVDRIGINIKIEFPEVYKWTKHMM 249 Query: 190 NLPTVKKFLQ 199 P V K L+ Sbjct: 250 RRPAVIKALR 259 >6GCB-A nrPDB Length = 325 Score = 45.3 bits (106), Expect = 2e-05, Method: Composition-based stats. Identities = 27/122 (22%), Positives = 52/122 (42%), Gaps = 14/122 (11%) Query: 80 NLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAKIALIKEKTKSRYFPAFEKV 139 +LY + +K ID E + D + ++ + A+I EK+ Sbjct: 167 HLYPEALKSE--IDEINEWVYDTVNNGVYKAGFATTQQAYEAAVIP---LFESLDRLEKI 221 Query: 140 LQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLISNFP-LLKALKTRISNLPTVKKFL 198 L G+DYLVG++L+ AD+ L + D + + +F L+ ++ P + +L Sbjct: 222 L--TGKDYLVGDQLTEADVRLFVTII---RFDPAYVGHFKCNLRTIRD---GYPAIHLWL 273 Query: 199 QP 200 + Sbjct: 274 RK 275 >4FQU-A nrPDB Length = 313 Score = 44.1 bits (103), Expect = 4e-05, Method: Composition-based stats. Identities = 26/151 (17%), Positives = 56/151 (37%), Gaps = 18/151 (11%) Query: 67 QTRAILNYIASKYNLYGKDI------KERALIDMYTEGMADLNEMILLLPLCRPEEKDAK 120 ++ I+ + S ++ G + R ID + + + ++ + Sbjct: 137 ESSEIIRILNSAFDDVGALPGDYYPAEFRPEIDRINARVYETLNNGVYRSGFATTQEAYE 196 Query: 121 IALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLY-----YVEELDSSL- 174 A E+ L G+++LVG++L+ ADI L L Y +L Sbjct: 197 EAFYP---LFDTLDWLEEHL--TGREWLVGDRLTEADIRLFPTLVRFDAIYHGHFKCNLR 251 Query: 175 -ISNFPLLKALKTRISNLPTVKKFLQPGSPR 204 I+++P L L ++++ V + + Sbjct: 252 RIADYPNLSRLVGKLASHERVAPTINLRHAK 282 >5IQY-A nrPDB Length = 216 Score = 43.3 bits (101), Expect = 7e-05, Method: Composition-based stats. Identities = 31/160 (19%), Positives = 58/160 (36%), Gaps = 27/160 (16%) Query: 17 EPIRWLLAAAGVEFEEKFI---GSAEDLGKLRNDGSLMFQQVPMVEI-DGMKLVQTRAIL 72 + + L + +E K + E K+ + +VP+ DG + + I Sbjct: 27 QRVLLTLEEKKITYEMKLVDLSNKPEWFLKISPE-----GKVPVFNSGDGKWIADSDVIT 81 Query: 73 NYIASKY---NLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAKIALIKEKTK 129 I K+ +L E A + + P K + EK Sbjct: 82 QVIEEKFPTPSLV--TPPEYASV------------GSKIFPSFVKFLKSKDASDGSEKAL 127 Query: 130 SRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEE 169 A ++ L++HG Y+ G +S AD+SL L++++ Sbjct: 128 LDELQALDEHLKAHG-PYISGENVSAADLSLGPKLFHLQV 166 >3BBY-A nrPDB Length = 215 Score = 43.3 bits (101), Expect = 8e-05, Method: Composition-based stats. Identities = 19/81 (23%), Positives = 35/81 (43%), Gaps = 9/81 (11%) Query: 23 LAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQ--QVPMVEIDGMKLVQTRAILNYIASKY- 79 L G+ F K I + L+ Q +VP+++ID +L ++ AI Y+ ++ Sbjct: 27 LQEKGLSFHIKTI-DLDSGEHLQPTWQGYGQTRRVPLLQIDDFELSESSAIAEYLEDRFA 85 Query: 80 -----NLYGKDIKERALIDMY 95 +Y D++ RA Sbjct: 86 PPTWERIYPLDLENRARARQI 106 >4G0L-A nrPDB Length = 328 Score = 41.8 bits (97), Expect = 2e-04, Method: Composition-based stats. Identities = 31/159 (19%), Positives = 55/159 (34%), Gaps = 21/159 (13%) Query: 54 QVPMVEIDG-MKLV--QTRAILNYIASKYNLYGKD------IKERALIDMYTEGMADLNE 104 VP++ +V ++ I+ + ++ G + ID + D Sbjct: 132 TVPVLWDKKNHTIVSNESAEIIRMFNTAFDALGAKAGDYYPPALQTKIDELNGWIYDTVN 191 Query: 105 MILLLPLCRPEEKDAKIALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELL 164 + ++ A+ K E++L H YL GN+L+ ADI L L Sbjct: 192 NGVYKAGFATSQEAYDEAVAK---VFESLARLEQILGQH--RYLTGNQLTEADIRLWTTL 246 Query: 165 -----YYVEEL--DSSLISNFPLLKALKTRISNLPTVKK 196 YV D IS++ L I +P + + Sbjct: 247 VRFDPVYVTHFKCDKHRISDYLNLYGFLRDIYQMPGIAE 285 >1GWC-A nrPDB Length = 230 Score = 41.8 bits (97), Expect = 3e-04, Method: Composition-based stats. Identities = 40/196 (20%), Positives = 69/196 (35%), Gaps = 27/196 (13%) Query: 19 IRWLLAAAGVEFEEKFIGSAEDLGK---LRNDGSLMFQQVPMVEIDGMKLVQTRAILNYI 75 ++ LA G+ +E+ EDL K L + + +++P++ +G + ++ IL YI Sbjct: 21 VKLALALKGLSYEDV----EEDLYKKSELLLKSNPVHKKIPVLIHNGAPVCESMIILQYI 76 Query: 76 ASKY-----NLYGKDIKERALIDMYTEGMADLN----EMILLLPLCRPEEKDAKIALIKE 126 + +L D ERA+ + + D L + + K A Sbjct: 77 DEVFASTGPSLLPADPYERAIARFWVAYVDDKLVAPWRQWLRGKTEEEKSEGKKQAFAAV 136 Query: 127 KTKSRYFPAFEKVLQSHGQ------DYLVGNKLSRADISLVELLYYVEELDSSLISNFPL 180 K G D +G LS + + E L + D++ PL Sbjct: 137 GVLEGALRECSKGGGFFGGDGVGLVDVALGGVLSW--MKVTEALSGDKIFDAAKT---PL 191 Query: 181 LKALKTRISNLPTVKK 196 L A R L K Sbjct: 192 LAAWVERFIELDAAKA 207 >4USS-A nrPDB Length = 325 Score = 40.3 bits (93), Expect = 7e-04, Method: Composition-based stats. Identities = 31/171 (18%), Positives = 64/171 (37%), Gaps = 26/171 (15%) Query: 54 QVPMVEIDGMKLV---QTRAILNYIASKYN---------LYGKDIKERALIDMYTEGMAD 101 VP++ +K + ++ I+ +++N LY + +A ID + D Sbjct: 128 TVPVLWDKKLKTIVNNESSEIIRMFNTEFNDIAENAALDLYPSHL--QAQIDETNGWVYD 185 Query: 102 LNEMILLLPLCRPEEKDAKIALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLV 161 + ++ + A I+ E++L Q Y+ GN LS ADI L Sbjct: 186 GINNGVYKCGFARKQGPYEEAAIQ---LYEALDKCEEILGR--QRYICGNTLSEADIKLF 240 Query: 162 ELLYYVEEL-------DSSLISNFPLLKALKTRISNLPTVKKFLQPGSPRK 205 L +E+ + L+ ++P + I +P + + ++ Sbjct: 241 VTLIRFDEVYAVHFKCNKKLLRDYPNMFNYTKDIFQIPGMSSTVNMQHIKR 291 >6GZF-A nrPDB Length = 341 Score = 39.5 bits (91), Expect = 0.001, Method: Composition-based stats. Identities = 22/123 (17%), Positives = 49/123 (39%), Gaps = 20/123 (16%) Query: 54 QVPMV---EIDGMKLVQTRAILNYIASKYN--------LYGKDIKERALIDMYTEGM-AD 101 VP++ E D + ++ I+ ++++ LY + +E+ +D + + Sbjct: 133 TVPVLWDTEEDTIVNNESEEIMRMFDTEFDEFADHTVDLYPEGYQEK--VDQIIDNIYEP 190 Query: 102 LNEMILLLPLCRPEEKDAKIALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLV 161 +N + +E + ++ VL Q YL G++L+ ADI++ Sbjct: 191 INNGVYRAGFATEQEPYDEAVA----ELFGALAHWDDVLAD--QRYLAGDRLTEADIAMF 244 Query: 162 ELL 164 L Sbjct: 245 TTL 247 >4PTS-A nrPDB Length = 348 Score = 36.8 bits (84), Expect = 0.008, Method: Composition-based stats. Identities = 26/119 (21%), Positives = 51/119 (42%), Gaps = 17/119 (14%) Query: 81 LYGKDIKERALIDMYTEGM-ADLNEMILLLPLCRPEEK-DAKIALIKEKTKSRYFPAFEK 138 LY + + RA ID ++G+ ++N + ++ DA + K + Sbjct: 162 LYPEHL--RAEIDEVSKGIYTEVNNGVYRCGFAGSQDAYDAAYDRLFTK-----LDELSE 214 Query: 139 VLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLISNFPLLKALKTRISNLPTVKKF 197 L Q YLVG+ ++ AD+ L L D+ +F K ++++S +P + + Sbjct: 215 RLAQ--QRYLVGDTITEADVRLFTTLA---RFDAVYHGHF---KCNRSKLSEMPVLWAY 265 >2JZR-A nrPDB Length = 144 Score = 36.4 bits (83), Expect = 0.011, Method: Composition-based stats. Identities = 13/52 (25%), Positives = 24/52 (46%), Gaps = 2/52 (3%) Query: 34 FIGSAEDLGKLRNDGSLMFQQVPMVEIDGMKLVQTRAILNYIASKYNLYGKD 85 F+ +D + L + ++P+V +G + Q+ I Y + L GKD Sbjct: 68 FLHEKKDGDFQKWYAGLNYPKLPVVTDNGGTIAQSLNISVY--PSWALIGKD 117 >3M1G-A nrPDB Length = 362 Score = 35.2 bits (80), Expect = 0.021, Method: Composition-based stats. Identities = 16/67 (23%), Positives = 31/67 (46%), Gaps = 8/67 (11%) Query: 133 FPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLISNFPLLKALKTRISNLP 192 E L + + YL+G+ ++ ADI L L D+ +F K + +I+ +P Sbjct: 223 LDWLEDRLST--RRYLMGDHITEADIRLYPTLV---RFDAVYHGHF---KCGRNKITEMP 274 Query: 193 TVKKFLQ 199 + +L+ Sbjct: 275 NLWGYLR 281 >3FY7-A nrPDB Length = 250 Score = 34.5 bits (78), Expect = 0.039, Method: Composition-based stats. Identities = 26/175 (14%), Positives = 55/175 (31%), Gaps = 25/175 (14%) Query: 16 MEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQVPMVEIDGMKLVQTRAILNYI 75 + + +L GV F + + L++ Q+P++ D T I +++ Sbjct: 45 CQRLFMVLLLKGVPFTLTTVDTRRSPDVLKD--FAPGSQLPILLYDSDAKTDTLQIEDFL 102 Query: 76 ASKYN------LYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAKIALIKEKTK 129 L R D+ +D + + Sbjct: 103 EETLGPPDFPSLAP-----RYRES--NTAGNDVFHKFSAFIKNPVPAQDEALYQQLLRAL 155 Query: 130 SRYFPAF----------EKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSL 174 +R E L+ + +L G++L+ AD SL+ L+ V+ + + Sbjct: 156 ARLDSYLRAPLEHELAGEPQLRESRRRFLDGDRLTLADCSLLPKLHIVDTVCAHF 210 >2C5J-A nrPDB Length = 95 Score = 32.9 bits (74), Expect = 0.11, Method: Composition-based stats. Identities = 24/89 (26%), Positives = 38/89 (42%), Gaps = 11/89 (12%) Query: 51 MFQQVPMVEIDGMKLVQTRAILNYIASKYNLYGKDIKERALIDM---YTEGMADLNEMIL 107 FQQV V+ +L I NYI +N G D +E + D+ E + DL+ I+ Sbjct: 7 PFQQV--VKDTKEQL---NRINNYITR-HNTAGDDDQEEEIQDILKDVEETIVDLDRSII 60 Query: 108 LLPLCRPEEKDAKIALIKEKTKSRYFPAF 136 ++ R E +D + K + A Sbjct: 61 VMK--RDENEDVSGREAQVKNIKQQLDAL 87 >4LMW-A nrPDB Length = 251 Score = 32.9 bits (74), Expect = 0.12, Method: Composition-based stats. Identities = 34/225 (15%), Positives = 74/225 (32%), Gaps = 49/225 (21%) Query: 17 EPIRWLLAAAGVEFEEKFIGSAEDLGKL----------RNDGSLMFQQVPMVEIDGMK-- 64 R++L G+++ +++ D+ + + +P+++ K Sbjct: 26 WKTRYVLNFKGLKYRTEWVE-YPDIEAVCKQIGAPATEKKPDGRDHYTLPVIQDPNTKAV 84 Query: 65 LVQTRAILNYIASKY----NLYGKD---------IKERALIDMYTEGMADLNEMILLLP- 110 + + AI Y+ S Y L+ + R + M + LL P Sbjct: 85 VADSDAIAKYLESTYPDTPRLFPEGTRAFQHAFYQLARPSVLMPIFNIVVARVWKLLRPR 144 Query: 111 ---LCRPEEKDAKIALIKEKTKSRYFPAFE-------KVLQSHGQD---YLVGNKLSRAD 157 R + ++E + A E L+++G L+G++++ AD Sbjct: 145 SQEYFRATREQMLGKKLEEIGSEDDWNALESGLARIKSSLEANGAGKDLLLMGDRVTFAD 204 Query: 158 ISLVELLYYVEELDSSLISNFPLLKALKTRISNLP--TVKKFLQP 200 + L L ++ + R +L KF+Q Sbjct: 205 LQLASLFIWLRVSAGEESED-------WKRFLSLHEGKWAKFMQQ 242 >4XRU-B nrPDB Length = 394 Score = 32.2 bits (72), Expect = 0.18, Method: Composition-based stats. Identities = 30/153 (19%), Positives = 67/153 (43%), Gaps = 6/153 (3%) Query: 64 KLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPE-EKDAKIA 122 K+ Q A L+++A L K++K++ + + + + + L LP + + + Sbjct: 161 KIQQEPAYLSFVADAKVLSAKELKDKYPMHIIRQYQSIRDFKFLDLPHYQQNIQLFKRQL 220 Query: 123 LIKEKTKSRYFPAFE--KVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLISNFPL 180 I K + +F F K + + G+++ V + LS I+ + L+Y + +P Sbjct: 221 DIFGKEAAPFFKPFNILKEVYTDGREHFVNDNLSFQQINDDDFLHYQFTDREDFEAKYPQ 280 Query: 181 LKALKTRISNLPTVKKFLQPGS---PRKPPADA 210 ++A +++ ++P + P PPA Sbjct: 281 IRAWVDQVNQSDEEGVVIKPRTAFLPGMPPAFK 313 >2H30-A nrPDB Length = 164 Score = 32.2 bits (72), Expect = 0.20, Method: Composition-based stats. Identities = 13/52 (25%), Positives = 23/52 (44%), Gaps = 2/52 (3%) Query: 34 FIGSAEDLGKLRNDGSLMFQQVPMVEIDGMKLVQTRAILNYIASKYNLYGKD 85 F+ +D + L + ++P+V +G + Q I Y + L GKD Sbjct: 82 FLHEKKDGEFQKWYAGLNYPKLPVVTDNGGTIAQNLNISVY--PSWALIGKD 131 >5Y7I-A nrPDB Length = 261 Score = 31.4 bits (70), Expect = 0.33, Method: Composition-based stats. Identities = 23/170 (13%), Positives = 56/170 (32%), Gaps = 25/170 (14%) Query: 16 MEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQVPMVEIDGMKLVQTRAILNYI 75 + + +L GV+F + + +L++ P + +G I ++ Sbjct: 49 CQRLFMVLWLKGVKFTVTTVDMRKKPAELKDLA--PGTNPPFLLYNGTLKTDFIKIEEFL 106 Query: 76 ASKY------NLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAKIALIKE-KT 128 +L + + + AD+ P + L++E K Sbjct: 107 EQTLAPPRYPHLSPVNKES-------FDVGADIFAKFSAFIKNSPNNPLQEKNLLREFKR 159 Query: 129 KSRYFP-AFEKVLQSHG--------QDYLVGNKLSRADISLVELLYYVEE 169 Y + + + + +L G++L+ AD +L+ L+ + Sbjct: 160 LDDYLNSPLPEEIDHNSVETITVSNRKFLDGDRLTLADCNLLPKLHVIRV 209 >5LKB-A nrPDB Length = 378 Score = 31.0 bits (69), Expect = 0.37, Method: Composition-based stats. Identities = 17/80 (21%), Positives = 35/80 (43%), Gaps = 5/80 (6%) Query: 100 ADLNEMILLLPLCRPEEKDAKIALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADIS 159 A++ E + ++ + ++ K K++Y E + G+ + VG++L+ ADI Sbjct: 232 AEVYESEVNNVFEHLDKVEKILSDKYSKLKAKYGE--EDRQKILGEFFTVGDQLTEADIR 289 Query: 160 LVELLYYVEELDSSLISNFP 179 L V D + +F Sbjct: 290 LYTT---VIRFDPVYVQHFK 306 >2YV7-A nrPDB Length = 260 Score = 31.0 bits (69), Expect = 0.39, Method: Composition-based stats. Identities = 30/190 (15%), Positives = 69/190 (36%), Gaps = 23/190 (12%) Query: 40 DLGKLRNDGSLMFQQV--PMVEIDGMKLVQTRAILNYIASK----YNLYGKDIKERALID 93 D+ K D F+ P++ +G+ +++ I +I YNL+ +D + Sbjct: 67 DMQKPPPDFRTNFEATHPPILIDNGLAILENEKIERHIMKNIPGGYNLFVQDKE------ 120 Query: 94 MYTEGMADLNEMILLLPLCRPEEKDAKIALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKL 153 + +L + L+ + + E K + L + +L G+ + Sbjct: 121 -VATLIENLYVKLKLMLVKKDE--------AKNNALLSHLRKINDHLSARNTRFLTGDTM 171 Query: 154 SRADISLVELLYYVEELDSSLIS-NFP-LLKALKTRISNLPTVKKFLQPGSPRKPPADAK 211 D L+ L ++ + P L AL + ++ + F Q + + Sbjct: 172 CCFDCELMPRLQHIRVAGKYFVDFEIPTHLTALWRYMYHMYQLDAFTQSCPADQDIINHY 231 Query: 212 ALEEARKIFR 221 L+++ K+ + Sbjct: 232 KLQQSLKMKK 241 >3H2Z-A nrPDB Length = 382 Score = 31.0 bits (69), Expect = 0.44, Method: Composition-based stats. Identities = 23/138 (16%), Positives = 48/138 (34%), Gaps = 19/138 (13%) Query: 32 EKFIGSAEDLGKLRNDGSLMFQQVPMVEIDG----------MKLVQTRAILNYIASKYNL 81 E + + + + +P +E+ L AI Y+ L Sbjct: 173 EVTVETFSEWIVDKTQFKGALPNIPGMELTDNLMAFVERKLFTLNTGHAITAYLGK---L 229 Query: 82 YG-KDIKERAL---IDMYTEGMADLNEMILLLPLCRPEEKD-AKIALIKEKTKSRYF-PA 135 G + I++ L I +G + + +L+ +K A I I + ++ Y Sbjct: 230 AGHQTIRDAILDEKIRAVVKGAMEESGAVLIKRYGFDADKHAAYIQKILGRFENPYLKDD 289 Query: 136 FEKVLQSHGQDYLVGNKL 153 E+V + + G++L Sbjct: 290 VERVGRQPLRKLSAGDRL 307 >3QAO-A nrPDB Length = 249 Score = 31.0 bits (69), Expect = 0.47, Method: Composition-based stats. Identities = 14/86 (16%), Positives = 29/86 (33%), Gaps = 1/86 (1%) Query: 63 MKLVQTR-AILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAKI 121 + L ++ A ++AS L + + + ID + + D + I L + Sbjct: 160 LTLKESFDAEFRHLASVRKLTPESEEAQLEIDHFFHYLNDTHGNIYSLEAFASLGEMYVN 219 Query: 122 ALIKEKTKSRYFPAFEKVLQSHGQDY 147 K ++ + LQ Y Sbjct: 220 DERFTKNIDQFGDGLSQFLQEAMTIY 245 >4K0G-A nrPDB Length = 251 Score = 30.2 bits (67), Expect = 0.74, Method: Composition-based stats. Identities = 26/166 (15%), Positives = 51/166 (30%), Gaps = 25/166 (15%) Query: 21 WLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQVPMVEIDGMKLVQTRAILNYIASKYN 80 +L GV F + + ++ Q+P + T I ++ + Sbjct: 42 MVLWLKGVTFNVTTVDTKRRTETVQKL--CPGGQLPFLLYGTEVHTDTNKIEEFLEAV-- 97 Query: 81 LYG-KDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAKIALIKEKTKSRYFPAFEKV 139 L + K AL D+ + + + EK + + Sbjct: 98 LCPPRYPKLAALNPESNTAGLDIFAKFSAYI----KNSNPALNDNLEKGLLKALKVLDNY 153 Query: 140 LQS----------------HGQDYLVGNKLSRADISLVELLYYVEE 169 L S + +L GN+L+ AD +L+ L+ V+ Sbjct: 154 LTSPLPEEVDETSAEDEGVSQRKFLDGNELTLADCNLLPKLHIVQV 199 >1OYJ-A nrPDB Length = 231 Score = 29.1 bits (64), Expect = 1.6, Method: Composition-based stats. Identities = 16/66 (24%), Positives = 32/66 (48%), Gaps = 5/66 (7%) Query: 16 MEPIRWLLAAAGVEFE--EKFIGSAEDLGKLRNDGSLMFQQVPMVEIDGMKLVQTRAILN 73 + R +A G+EFE E+ +G+ DL N +++P++ G + ++ IL Sbjct: 18 GQRCRIAMAEKGLEFEYREEDLGNKSDLLLRSNPVH---RKIPVLLHAGRPVSESLVILQ 74 Query: 74 YIASKY 79 Y+ + Sbjct: 75 YLDDAF 80 >2OCA-A nrPDB Length = 510 Score = 29.1 bits (64), Expect = 1.8, Method: Composition-based stats. Identities = 20/121 (16%), Positives = 39/121 (32%), Gaps = 11/121 (9%) Query: 27 GVEFEEKFIGSAE----DLGKLRNDGSLMFQQVPMVEIDGMKLVQTRAILNYIAS----- 77 G ++K+ A + F Q M+ D L ++I + I+ Sbjct: 194 GASKDDKYKNDAPVVVGTWQTVVKQPKEWFSQFGMMMNDECHLATGKSISSIISGLNNCM 253 Query: 78 -KYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEE-KDAKIALIKEKTKSRYFPA 135 K+ L G +A I Y ++ + + L + + KI I + + Sbjct: 254 FKFGLSGSLRDGKANIMQYVGMFGEIFKPVTTSKLMEDGQVTELKINSIFLRYPDEFTTK 313 Query: 136 F 136 Sbjct: 314 L 314 >2JB2-A nrPDB Length = 489 Score = 28.7 bits (63), Expect = 2.0, Method: Composition-based stats. Identities = 12/44 (27%), Positives = 17/44 (38%) Query: 113 RPEEKDAKIALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRA 156 E A A P +EK+L+ + Y G+ LS A Sbjct: 420 YSESAWANWAGSGGSHGGAATPEYEKLLEPVDKIYFAGDHLSNA 463 >4CZI-A nrPDB Length = 348 Score = 28.7 bits (63), Expect = 2.2, Method: Composition-based stats. Identities = 11/35 (31%), Positives = 19/35 (54%), Gaps = 3/35 (8%) Query: 58 VEIDGMKLVQTRAILNYIASKYNLY-GKDIKERAL 91 V + G K+ + AI++Y+ +NL G+ ER Sbjct: 177 VRVGGDKMDE--AIISYMRRHHNLLIGETTAERIK 209 >3H6J-A nrPDB Length = 438 Score = 28.3 bits (62), Expect = 2.7, Method: Composition-based stats. Identities = 9/42 (21%), Positives = 17/42 (40%) Query: 16 MEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQVPM 57 + L AA GV +E K++ S++ ++ P Sbjct: 139 ARYVIPLYAATGVNYELKWLESSDGGETWGEGSTIYSGNTPY 180 >5C8D-A nrPDB Length = 305 Score = 27.9 bits (61), Expect = 3.6, Method: Composition-based stats. Identities = 8/32 (25%), Positives = 15/32 (46%) Query: 186 TRISNLPTVKKFLQPGSPRKPPADAKALEEAR 217 + L T+K++L+ G+ K +E R Sbjct: 68 EDVEALKTIKRWLEEGATPKAAIRRYLAQEVR 99 >5CJH-A nrPDB Length = 764 Score = 27.5 bits (60), Expect = 4.0, Method: Composition-based stats. Identities = 8/26 (30%), Positives = 14/26 (53%) Query: 150 GNKLSRADISLVELLYYVEELDSSLI 175 GNK+S AD+ L+ +E + + Sbjct: 167 GNKISWADLMLLTGNVALENMGFKTL 192 >2D2Z-A nrPDB Length = 261 Score = 26.8 bits (58), Expect = 8.2, Method: Composition-based stats. Identities = 8/52 (15%), Positives = 22/52 (42%) Query: 122 ALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSS 173 + + ++ + +L GN+++ AD +L+ L+ V+ + Sbjct: 153 EYLNSPLPDEIDENSMEDIKFSTRKFLDGNEMTLADCNLLPKLHIVKVVAKK 204 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.312 0.152 0.430 Lambda K H 0.267 0.0466 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 9,615,129 Number of Sequences: 36641 Number of extensions: 417036 Number of successful extensions: 1720 Number of sequences better than 10.0: 146 Number of HSP's better than 10.0 without gapping: 180 Number of HSP's successfully gapped in prelim test: 59 Number of HSP's that attempted gapping in prelim test: 1284 Number of HSP's gapped (non-prelim): 245 length of query: 222 length of database: 10,336,785 effective HSP length: 93 effective length of query: 129 effective length of database: 6,929,172 effective search space: 893863188 effective search space used: 893863188 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 58 (26.8 bits)