BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q16719 (465 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 3E9K-A nrPDB 963 0.0 1QZ9-A nrPDB 158 4e-39 3LVM-A nrPDB 37 0.025 2BKW-A nrPDB 36 0.027 1VJO-A nrPDB 33 0.26 2DR1-A nrPDB 33 0.30 3PEW-A nrPDB 30 2.1 1N7Z-A nrPDB 30 2.1 4BF9-A nrPDB 30 2.5 1TY8-A nrPDB 30 2.7 1M1B-A nrPDB 30 2.9 5XT5-A nrPDB 29 3.3 3RUY-A nrPDB 29 3.5 3IXV-A nrPDB 28 9.9 >3E9K-A nrPDB Length = 465 Score = 963 bits (2489), Expect = 0.0, Method: Compositional matrix adjust. Identities = 465/465 (100%), Positives = 465/465 (100%) Query: 1 MEPSSLELPADTVQRIAAELKCHPTDERVALHLDEEDKLRHFRECFYIPKIQDLPPVDLS 60 MEPSSLELPADTVQRIAAELKCHPTDERVALHLDEEDKLRHFRECFYIPKIQDLPPVDLS Sbjct: 1 MEPSSLELPADTVQRIAAELKCHPTDERVALHLDEEDKLRHFRECFYIPKIQDLPPVDLS 60 Query: 61 LVNKDENAIYFLGNSLGLQPKMVKTYLEEELDKWAKIAAYGHEVGKRPWITGDESIVGLM 120 LVNKDENAIYFLGNSLGLQPKMVKTYLEEELDKWAKIAAYGHEVGKRPWITGDESIVGLM Sbjct: 61 LVNKDENAIYFLGNSLGLQPKMVKTYLEEELDKWAKIAAYGHEVGKRPWITGDESIVGLM 120 Query: 121 KDIVGANEKEIALMNALTVNLHLLMLSFFKPTPKRYKILLEAKAFPSDHYAIESQLQLHG 180 KDIVGANEKEIALMNALTVNLHLLMLSFFKPTPKRYKILLEAKAFPSDHYAIESQLQLHG Sbjct: 121 KDIVGANEKEIALMNALTVNLHLLMLSFFKPTPKRYKILLEAKAFPSDHYAIESQLQLHG 180 Query: 181 LNIEESMRMIKPREGEETLRIEDILEVIEKEGDSIAVILFSGVHFYTGQHFNIPAITKAG 240 LNIEESMRMIKPREGEETLRIEDILEVIEKEGDSIAVILFSGVHFYTGQHFNIPAITKAG Sbjct: 181 LNIEESMRMIKPREGEETLRIEDILEVIEKEGDSIAVILFSGVHFYTGQHFNIPAITKAG 240 Query: 241 QAKGCYVGFDLAHAVGNVELYLHDWGVDFACWCSYKYLNAGAGGIAGAFIHEKHAHTIKP 300 QAKGCYVGFDLAHAVGNVELYLHDWGVDFACWCSYKYLNAGAGGIAGAFIHEKHAHTIKP Sbjct: 241 QAKGCYVGFDLAHAVGNVELYLHDWGVDFACWCSYKYLNAGAGGIAGAFIHEKHAHTIKP 300 Query: 301 ALVGWFGHELSTRFKMDNKLQLIPGVCGFRISNPPILLVCSLHASLEIFKQATMKALRKK 360 ALVGWFGHELSTRFKMDNKLQLIPGVCGFRISNPPILLVCSLHASLEIFKQATMKALRKK Sbjct: 301 ALVGWFGHELSTRFKMDNKLQLIPGVCGFRISNPPILLVCSLHASLEIFKQATMKALRKK 360 Query: 361 SVLLTGYLEYLIKHNYGKDKAATKKPVVNIITPSHVEERGCQLTITFSVPNKDVFQELEK 420 SVLLTGYLEYLIKHNYGKDKAATKKPVVNIITPSHVEERGCQLTITFSVPNKDVFQELEK Sbjct: 361 SVLLTGYLEYLIKHNYGKDKAATKKPVVNIITPSHVEERGCQLTITFSVPNKDVFQELEK 420 Query: 421 RGVVCDKRNPNGIRVAPVPLYNSFHDVYKFTNLLTSILDSAETKN 465 RGVVCDKRNPNGIRVAPVPLYNSFHDVYKFTNLLTSILDSAETKN Sbjct: 421 RGVVCDKRNPNGIRVAPVPLYNSFHDVYKFTNLLTSILDSAETKN 465 >1QZ9-A nrPDB Length = 416 Score = 158 bits (400), Expect = 4e-39, Method: Compositional matrix adjust. Identities = 114/435 (26%), Positives = 196/435 (45%), Gaps = 48/435 (11%) Query: 31 LHLDEEDKLRHFRECFYIPKIQDLPPVDLSLVNKDENAIYFLGNSLGLQPKMVKTYLEEE 90 L LD +D L R+ F +P E IY GNSLG +P + Sbjct: 8 LALDAQDSLAPLRQQFALP----------------EGVIYLDGNSLGARPVAALARAQAV 51 Query: 91 L-DKWAKIAAYGHEVGKRPWITGDESIVGLMKDIVGANEKEIALMNALTVNLHLLMLSFF 149 + ++W W E + + ++GA + E+ + + ++NL ++ + Sbjct: 52 IAEEWGN--GLIRSWNSAGWRDLSERLGNRLATLIGARDGEVVVTDTTSINLFKVLSAAL 109 Query: 150 K----PTPKRYKILLEAKAFPSDHYAIESQLQLHGLNIEESMRMIKPREGEETLRIEDIL 205 + +P+R I+ E FP+D Y E + L ++R++ E ++ Sbjct: 110 RVQATRSPERRVIVTETSNFPTDLYIAEGLADM--LQQGYTLRLVDSPE--------ELP 159 Query: 206 EVIEKEGDSIAVILFSGVHFYTGQHFNIPAITKAGQAKGCYVGFDLAHAVGNVELYLHDW 265 + I+++ AV++ + V++ TG ++ A+T G +DLAH+ G V + LH Sbjct: 160 QAIDQD---TAVVMLTHVNYKTGYMHDMQALTALSHECGALAIWDLAHSAGAVPVDLHQA 216 Query: 266 GVDFACWCSYKYLNAGAGGIAGAFIHEKHAHTIKPALVGWFGHELSTRFKMDNKLQLIPG 325 G D+A C+YKYLN G G A ++ + + L GWFGH S +F M+ + + G Sbjct: 217 GADYAIGCTYKYLNGGPGSQAFVWVSPQLCDLVPQPLSGWFGH--SRQFAMEPRYEPSNG 274 Query: 326 VCGFRISNPPILLVCSLHASLEIFKQATMKALRKKSVLLTGYLEYLIKHNYGKDKAATKK 385 + + PI + + L++F Q M +LR+KS+ LT L++ + Sbjct: 275 IARYLCGTQPITSLAMVECGLDVFAQTDMASLRRKSLALTDLFIELVEQRCAAHE----- 329 Query: 386 PVVNIITPSHVEERGCQLTITFSVPNK-DVFQELEKRGVVCDKRNPNGIRVAPVPLYNSF 444 + ++TP +RG ++F P V Q L RGV+ D R P +R PLY +F Sbjct: 330 --LTLVTPREHAKRGSH--VSFEHPEGYAVIQALIDRGVIGDYREPRIMRFGFTPLYTTF 385 Query: 445 HDVYKFTNLLTSILD 459 +V+ +L ILD Sbjct: 386 TEVWDAVQILGEILD 400 >3LVM-A nrPDB Length = 423 Score = 36.6 bits (83), Expect = 0.025, Method: Compositional matrix adjust. Identities = 47/201 (23%), Positives = 84/201 (41%), Gaps = 25/201 (12%) Query: 120 MKDIVGANEKEIALMNALTVNLHLLMLSFFKPTPKRYKILLEAKAFPSDHYAIES---QL 176 + D+VGA+ +EI + T + +L + K+ K ++ +K ++H A+ QL Sbjct: 77 IADLVGADPREIVFTSGATESDNLAIKGAANFYQKKGKHIITSK---TEHKAVLDTCRQL 133 Query: 177 QLHGLNIE----ESMRMIKPREGEETLRIEDILEVIEKEGDSIAVILFSGVHFYTGQHFN 232 + G + + +I +E E +R + IL I + I V+ + Sbjct: 134 EREGFEVTYLAPQRNGIIDLKELEAAMRDDTILVSIMHVNNEIGVVQ------------D 181 Query: 233 IPAITKAGQAKGCYVGFDLAHAVGNVELYLHDWGVDFACWCSYKYLNAGAGGIAGAFIHE 292 I AI + +A+G D +VG + + L VD + +K G GI ++ Sbjct: 182 IAAIGEMCRARGIIYHVDATQSVGKLPIDLSQLKVDLMSFSGHKIY--GPKGIGALYVRR 239 Query: 293 KHAHTIKPALVGWFGHELSTR 313 K I+ + G GHE R Sbjct: 240 KPRVRIEAQMHGG-GHERGMR 259 >2BKW-A nrPDB Length = 385 Score = 36.2 bits (82), Expect = 0.027, Method: Compositional matrix adjust. Identities = 36/168 (21%), Positives = 72/168 (42%), Gaps = 10/168 (5%) Query: 118 GLMKDIVGANEKEIALMNALTVNLHLLMLSFFKPTPKRYKILLEAKAFPSDHYAIESQLQ 177 + K + + L + T+ + +F +L+ + SD +A L+ Sbjct: 49 AVFKSAAASKSQPFVLAGSGTLGWDIFASNFILSKAPNKNVLVVSTGTFSDRFA--DCLR 106 Query: 178 LHGLNIEESMRMIKPREGEETLRIEDILEVIEKEGDSIAVILFSGVHFYTGQHFNIPAIT 237 +G ++ +++P + E++ +E I E + + +S + + V T ++ AI+ Sbjct: 107 SYGAQVD----VVRPLKIGESVPLELITEKLSQ--NSYGAVTVTHVDTSTAVLSDLKAIS 160 Query: 238 KAGQAKGCYVGF--DLAHAVGNVELYLHDWGVDFACWCSYKYLNAGAG 283 +A + F D ++G E +WGVDFA S K + A AG Sbjct: 161 QAIKQTSPETFFVVDAVCSIGCEEFEFDEWGVDFALTASQKAIGAPAG 208 >1VJO-A nrPDB Length = 393 Score = 33.1 bits (74), Expect = 0.26, Method: Compositional matrix adjust. Identities = 21/87 (24%), Positives = 38/87 (43%), Gaps = 2/87 (2%) Query: 197 ETLRIEDILEVIEKEGDSIAVILFSGVHFYTGQHFNIPAITKAGQAKGCYVGFDLAHAVG 256 E +E++ +E +I ++ + TG + + + + G + D ++G Sbjct: 144 EVFSLEELRTALETHRPAILALVHA--ETSTGARQPLEGVGELCREFGTLLLVDTVTSLG 201 Query: 257 NVELYLHDWGVDFACWCSYKYLNAGAG 283 V ++L WGVD A CS K L G Sbjct: 202 GVPIFLDAWGVDLAYSCSQKGLGCSPG 228 >2DR1-A nrPDB Length = 386 Score = 32.7 bits (73), Expect = 0.30, Method: Compositional matrix adjust. Identities = 34/155 (21%), Positives = 59/155 (38%), Gaps = 9/155 (5%) Query: 197 ETLRIEDILEVIEKEGDSIAVILFSGVHFYTGQHFNIPAITKAGQAKGCYVGFDLAHAVG 256 + ++ ED+ + + K D AV + TG +P + K + V D A+G Sbjct: 130 KAVKPEDLDDALRKNPDVEAVTITYN-ETSTGVLNPLPELAKVAKEHDKLVFVDAVSAMG 188 Query: 257 NVELYLHDWGVDFACWCSYKYLNAGAGGIAGAFIHEKHAHTIKPALVGWFGHELSTRFKM 316 ++ WG+D S K G GAF K GW+ ++ K Sbjct: 189 GADIKFDKWGLDVVFSSSQKAFGVPPGLAIGAFSERFLEIAEKMPERGWY-FDIPLYVKY 247 Query: 317 DNKLQLIPGVCGFRISNPPILLVCSLHASLEIFKQ 351 + + P S PP+ V ++ +L I ++ Sbjct: 248 LKEKESTP-------STPPMPQVFGINVALRIIEK 275 >3PEW-A nrPDB Length = 395 Score = 30.0 bits (66), Expect = 2.1, Method: Compositional matrix adjust. Identities = 13/38 (34%), Positives = 22/38 (57%) Query: 281 GAGGIAGAFIHEKHAHTIKPALVGWFGHELSTRFKMDN 318 G G+A +F+H+K++ I A+ +FG TR D+ Sbjct: 344 GRKGVAISFVHDKNSFNILSAIQKYFGDIEMTRVPTDD 381 >1N7Z-A nrPDB Length = 334 Score = 30.0 bits (66), Expect = 2.1, Method: Compositional matrix adjust. Identities = 18/56 (32%), Positives = 28/56 (50%), Gaps = 6/56 (10%) Query: 19 ELKCHPTDERVAL---HLDEEDKLRHFRECFYIPKIQDLPPVDLSLVNKDENAIYF 71 E K HP D V + D ED +RH E Y +++ PP+ +++ +E I F Sbjct: 280 EAKAHPNDPNVKAEKDYYDPEDLMRHSGEMIY---MENRPPIIMAMDQTEEINILF 332 >4BF9-A nrPDB Length = 338 Score = 30.0 bits (66), Expect = 2.5, Method: Compositional matrix adjust. Identities = 11/23 (47%), Positives = 12/23 (52%) Query: 262 LHDWGVDFACWCSYKYLNAGAGG 284 L WGVD C C K +N GG Sbjct: 110 LGSWGVDLNCGCPSKTVNGSGGG 132 >1TY8-A nrPDB Length = 284 Score = 29.6 bits (65), Expect = 2.7, Method: Compositional matrix adjust. Identities = 15/49 (30%), Positives = 26/49 (53%) Query: 322 LIPGVCGFRISNPPILLVCSLHASLEIFKQATMKALRKKSVLLTGYLEY 370 +IPG+C PPI+ S+ +L ++ + K+VL+ YL+Y Sbjct: 189 IIPGLCTGYAGVPPIISCKSMAFALRLYMAGDHISKELKNVLIMYYLQY 237 >1M1B-A nrPDB Length = 295 Score = 29.6 bits (65), Expect = 2.9, Method: Compositional matrix adjust. Identities = 16/41 (39%), Positives = 21/41 (51%), Gaps = 3/41 (7%) Query: 255 VGNVELYLHDWGVDFACWCSYKYLNAGAGGIAGAFIHEKHA 295 V VE ++ WG+D A + Y NAGA I +H K A Sbjct: 157 VARVEAFIAGWGLDEALKRAEAYRNAGADAI---LMHSKKA 194 >5XT5-A nrPDB Length = 419 Score = 29.3 bits (64), Expect = 3.3, Method: Compositional matrix adjust. Identities = 50/248 (20%), Positives = 93/248 (37%), Gaps = 27/248 (10%) Query: 48 IPKIQDLPPVDLSLVNKDENAIYFLGNSLGLQPKMVKTYLEEELDKWAKIAAYG-HEVGK 106 I I++ P+ VN + +Y + +P+ V L++ +++ G H +G Sbjct: 6 ITDIREQFPILHQQVNG-HDLVYLDSAATSQKPRAVIETLDKYYNQYNSNVHRGVHTLGT 64 Query: 107 RPWITGDESIVGLMKDIVGANEKEIALMNALTVNLHLLMLSFFKPTPKRYKILLEAKAFP 166 R + + + K I + EI T +L+++ LS+ + K P Sbjct: 65 RATDGYEGAREKVRKFINAKSMAEIIFTKGTTTSLNMVALSYARANLK-----------P 113 Query: 167 SDHYAIESQLQLHGLNIEESMRMIK---------PREGEETLRIEDILEVIEKEGDSIAV 217 D I H NI + +K P + + T+ +ED+ E + +AV Sbjct: 114 GDEVVI--TYMEHHANIIPWQQAVKATGATLKYIPLQEDGTISLEDVRETVTSNTKIVAV 171 Query: 218 ILFSGVHFYTGQHFNIPAITKAGQAKGCYVGFDLAHAVGNVELYLHDWGVDFACWCSYKY 277 S V G I + K G + D A + ++++ + D DF S+K Sbjct: 172 SHVSNV---LGTVNPIKEMAKIAHDNGAVIVVDGAQSTPHMKIDVQDLDCDFFALSSHKM 228 Query: 278 LNAGAGGI 285 G+ Sbjct: 229 CGPTGVGV 236 >3RUY-A nrPDB Length = 392 Score = 29.3 bits (64), Expect = 3.5, Method: Compositional matrix adjust. Identities = 30/124 (24%), Positives = 57/124 (45%), Gaps = 18/124 (14%) Query: 324 PGVCGFRISNPPILLVCSLHASLEIFKQATMKALRKKSVLLTGYLEYLIKHNYGKDKAAT 383 PG G P+ S+ A+LE+ ++ + L ++S+ L L +K Sbjct: 275 PGSHGSTFGGNPLACAVSI-AALEVLEE---EKLTERSLQLGEKLVGQLKE--------I 322 Query: 384 KKPVVNIITPSHVEERGCQLTITFSVPNKDVFQELEKRGVVCDKRNPNGIRVAPVPLYNS 443 P++ + V +G + I + P + ++L+ G++C + + N IR+AP PL S Sbjct: 323 DNPMI-----TEVRGKGLFIGIELNEPARPYCEQLKAAGLLCKETHENVIRIAP-PLVIS 376 Query: 444 FHDV 447 D+ Sbjct: 377 EEDL 380 >3IXV-A nrPDB Length = 626 Score = 27.7 bits (60), Expect = 9.9, Method: Compositional matrix adjust. Identities = 15/44 (34%), Positives = 22/44 (50%), Gaps = 7/44 (15%) Query: 8 LPADTVQRIAAELKCHPTDERVALH-------LDEEDKLRHFRE 44 +PA+T+ R E HP + + + LD E KL +FRE Sbjct: 119 VPAETINRANKEASNHPDQQSIVVEAEETGNILDPEYKLSYFRE 162 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 3E9K-A nrPDB 813 0.0 1QZ9-A nrPDB 599 e-172 Sequences not found previously or not previously below threshold: 4Q75-A nrPDB 59 5e-09 1VJO-A nrPDB 54 1e-07 3LVM-A nrPDB 53 3e-07 3WKR-A nrPDB 50 3e-06 5WT2-A nrPDB 47 1e-05 5WGB-A nrPDB 46 3e-05 6MRE-A nrPDB 46 3e-05 2BKW-A nrPDB 46 3e-05 2DR1-A nrPDB 46 4e-05 4W91-A nrPDB 44 2e-04 2YRI-A nrPDB 43 4e-04 1M32-A nrPDB 40 0.002 3KGX-A nrPDB 40 0.003 2CH1-A nrPDB 38 0.008 5LUC-A nrPDB 37 0.014 4WJB-A nrPDB 35 0.048 3CAI-A nrPDB 35 0.060 4ISY-A nrPDB 35 0.095 4EB7-A nrPDB 34 0.11 4MY5-A nrPDB 34 0.20 4BF9-A nrPDB 33 0.37 2DKJ-A nrPDB 31 1.1 4FUU-A nrPDB 31 1.2 3NZW-E nrPDB 31 1.2 4P3M-A nrPDB 30 1.9 3DHU-A nrPDB 30 2.0 1TY8-A nrPDB 30 2.8 4OTL-A nrPDB 29 3.8 1YJS-A nrPDB 29 5.2 6HEG-A nrPDB 29 6.8 1E5R-A nrPDB 28 8.8 >3E9K-A nrPDB Length = 465 Score = 813 bits (2100), Expect = 0.0, Method: Composition-based stats. Identities = 465/465 (100%), Positives = 465/465 (100%) Query: 1 MEPSSLELPADTVQRIAAELKCHPTDERVALHLDEEDKLRHFRECFYIPKIQDLPPVDLS 60 MEPSSLELPADTVQRIAAELKCHPTDERVALHLDEEDKLRHFRECFYIPKIQDLPPVDLS Sbjct: 1 MEPSSLELPADTVQRIAAELKCHPTDERVALHLDEEDKLRHFRECFYIPKIQDLPPVDLS 60 Query: 61 LVNKDENAIYFLGNSLGLQPKMVKTYLEEELDKWAKIAAYGHEVGKRPWITGDESIVGLM 120 LVNKDENAIYFLGNSLGLQPKMVKTYLEEELDKWAKIAAYGHEVGKRPWITGDESIVGLM Sbjct: 61 LVNKDENAIYFLGNSLGLQPKMVKTYLEEELDKWAKIAAYGHEVGKRPWITGDESIVGLM 120 Query: 121 KDIVGANEKEIALMNALTVNLHLLMLSFFKPTPKRYKILLEAKAFPSDHYAIESQLQLHG 180 KDIVGANEKEIALMNALTVNLHLLMLSFFKPTPKRYKILLEAKAFPSDHYAIESQLQLHG Sbjct: 121 KDIVGANEKEIALMNALTVNLHLLMLSFFKPTPKRYKILLEAKAFPSDHYAIESQLQLHG 180 Query: 181 LNIEESMRMIKPREGEETLRIEDILEVIEKEGDSIAVILFSGVHFYTGQHFNIPAITKAG 240 LNIEESMRMIKPREGEETLRIEDILEVIEKEGDSIAVILFSGVHFYTGQHFNIPAITKAG Sbjct: 181 LNIEESMRMIKPREGEETLRIEDILEVIEKEGDSIAVILFSGVHFYTGQHFNIPAITKAG 240 Query: 241 QAKGCYVGFDLAHAVGNVELYLHDWGVDFACWCSYKYLNAGAGGIAGAFIHEKHAHTIKP 300 QAKGCYVGFDLAHAVGNVELYLHDWGVDFACWCSYKYLNAGAGGIAGAFIHEKHAHTIKP Sbjct: 241 QAKGCYVGFDLAHAVGNVELYLHDWGVDFACWCSYKYLNAGAGGIAGAFIHEKHAHTIKP 300 Query: 301 ALVGWFGHELSTRFKMDNKLQLIPGVCGFRISNPPILLVCSLHASLEIFKQATMKALRKK 360 ALVGWFGHELSTRFKMDNKLQLIPGVCGFRISNPPILLVCSLHASLEIFKQATMKALRKK Sbjct: 301 ALVGWFGHELSTRFKMDNKLQLIPGVCGFRISNPPILLVCSLHASLEIFKQATMKALRKK 360 Query: 361 SVLLTGYLEYLIKHNYGKDKAATKKPVVNIITPSHVEERGCQLTITFSVPNKDVFQELEK 420 SVLLTGYLEYLIKHNYGKDKAATKKPVVNIITPSHVEERGCQLTITFSVPNKDVFQELEK Sbjct: 361 SVLLTGYLEYLIKHNYGKDKAATKKPVVNIITPSHVEERGCQLTITFSVPNKDVFQELEK 420 Query: 421 RGVVCDKRNPNGIRVAPVPLYNSFHDVYKFTNLLTSILDSAETKN 465 RGVVCDKRNPNGIRVAPVPLYNSFHDVYKFTNLLTSILDSAETKN Sbjct: 421 RGVVCDKRNPNGIRVAPVPLYNSFHDVYKFTNLLTSILDSAETKN 465 >1QZ9-A nrPDB Length = 416 Score = 599 bits (1545), Expect = e-172, Method: Composition-based stats. Identities = 114/435 (26%), Positives = 196/435 (45%), Gaps = 48/435 (11%) Query: 31 LHLDEEDKLRHFRECFYIPKIQDLPPVDLSLVNKDENAIYFLGNSLGLQPKMVKTYLEEE 90 L LD +D L R+ F +P E IY GNSLG +P + Sbjct: 8 LALDAQDSLAPLRQQFALP----------------EGVIYLDGNSLGARPVAALARAQAV 51 Query: 91 L-DKWAKIAAYGHEVGKRPWITGDESIVGLMKDIVGANEKEIALMNALTVNLHLLMLSFF 149 + ++W W E + + ++GA + E+ + + ++NL ++ + Sbjct: 52 IAEEWGN--GLIRSWNSAGWRDLSERLGNRLATLIGARDGEVVVTDTTSINLFKVLSAAL 109 Query: 150 K----PTPKRYKILLEAKAFPSDHYAIESQLQLHGLNIEESMRMIKPREGEETLRIEDIL 205 + +P+R I+ E FP+D Y E + L ++R++ E ++ Sbjct: 110 RVQATRSPERRVIVTETSNFPTDLYIAEGLADM--LQQGYTLRLVDSPE--------ELP 159 Query: 206 EVIEKEGDSIAVILFSGVHFYTGQHFNIPAITKAGQAKGCYVGFDLAHAVGNVELYLHDW 265 + I+++ AV++ + V++ TG ++ A+T G +DLAH+ G V + LH Sbjct: 160 QAIDQD---TAVVMLTHVNYKTGYMHDMQALTALSHECGALAIWDLAHSAGAVPVDLHQA 216 Query: 266 GVDFACWCSYKYLNAGAGGIAGAFIHEKHAHTIKPALVGWFGHELSTRFKMDNKLQLIPG 325 G D+A C+YKYLN G G A ++ + + L GWFGH S +F M+ + + G Sbjct: 217 GADYAIGCTYKYLNGGPGSQAFVWVSPQLCDLVPQPLSGWFGH--SRQFAMEPRYEPSNG 274 Query: 326 VCGFRISNPPILLVCSLHASLEIFKQATMKALRKKSVLLTGYLEYLIKHNYGKDKAATKK 385 + + PI + + L++F Q M +LR+KS+ LT L++ + Sbjct: 275 IARYLCGTQPITSLAMVECGLDVFAQTDMASLRRKSLALTDLFIELVEQRCAAHE----- 329 Query: 386 PVVNIITPSHVEERGCQLTITFSVPNK-DVFQELEKRGVVCDKRNPNGIRVAPVPLYNSF 444 + ++TP +RG ++F P V Q L RGV+ D R P +R PLY +F Sbjct: 330 --LTLVTPREHAKRGSH--VSFEHPEGYAVIQALIDRGVIGDYREPRIMRFGFTPLYTTF 385 Query: 445 HDVYKFTNLLTSILD 459 +V+ +L ILD Sbjct: 386 TEVWDAVQILGEILD 400 >4Q75-A nrPDB Length = 429 Score = 59.0 bits (141), Expect = 5e-09, Method: Composition-based stats. Identities = 66/351 (18%), Positives = 114/351 (32%), Gaps = 36/351 (10%) Query: 69 IYFLGNSLGLQPKMVKTYLEEELDKWAKIAAYGHEVGKRPWITGDESIVGLMKDIVGANE 128 +Y + +P V L+ + + G E + + A++ Sbjct: 40 VYLDSAATSQKPAAVLDALQNYYEFYNSNVHRGIHYLSAKATDEFELARKKVARFINASD 99 Query: 129 -KEIALMNALTVNLHLLM----LSFFKPTPKRYKILLEAKAFPSDHYAIESQLQLHGLNI 183 +EI T ++L+ LS KP + IL A +H++ Q+ Sbjct: 100 SREIVFTRNATEAINLVAYSWGLSNLKPGDE--VILTVA-----EHHSCIVPWQIVSQKT 152 Query: 184 EESMRMIKPREGEETLRIEDILEVIEKEGDSIAVILFSGVHFYTGQHFNIPAITKAGQAK 243 ++ + E +E I + E+I + +AV V I I Sbjct: 153 GAVLKFVTLNE-DEVPDINKLRELISPKTKLVAV---HHVSNVLASSLPIEEIVVWAHDV 208 Query: 244 GCYVGFDLAHAVGNVELYLHDWGVDFACWCSYKYLNAGAGGIAGAFIHEKHAHTIKPALV 303 G V D +V ++ + + DF S+K G GI + H++ P L Sbjct: 209 GAKVLVDACQSVPHMVVDVQKLNADFLVASSHKMC--GPTGIGFLYGKSDLLHSMPPFLG 266 Query: 304 GWFGHELSTRFKMDNKLQLIPGVCGFRISNPPILLVCSLHASLEIFKQATMKALRKKSVL 363 G G +S F + P F P I +L A+++ M + + V Sbjct: 267 G--GEMISDVFLDHSTYAEPP--SRFEAGTPAIGEAIALGAAVDYLSGIGMPKIHEYEVE 322 Query: 364 LTGYLEYLIKHNYGKDKAATKKPVVNIITPS--HVEERG--CQLTITFSVP 410 + YL + + P V I P RG C + P Sbjct: 323 IGKYL----------YEKLSSLPDVRIYGPRPSESVHRGALCSFNVEGLHP 363 >1VJO-A nrPDB Length = 393 Score = 54.0 bits (128), Expect = 1e-07, Method: Composition-based stats. Identities = 38/210 (18%), Positives = 68/210 (32%), Gaps = 22/210 (10%) Query: 170 YAIESQLQLHGLNIEESMRMIKPREGEETLRIEDILEVIEKEGDSIAVILFSGVHFYTGQ 229 Y + + G +R I GE +E++ +E A++ TG Sbjct: 119 YFGNRLVDMAG-RYGADVRTISKPWGE-VFSLEELRTALETHRP--AILALVHAETSTGA 174 Query: 230 HFNIPAITKAGQAKGCYVGFDLAHAVGNVELYLHDWGVDFACWCSYKYLNAGAGGIAGAF 289 + + + + G + D ++G V ++L WGVD A CS K L G Sbjct: 175 RQPLEGVGELCREFGTLLLVDTVTSLGGVPIFLDAWGVDLAYSCSQKGLGCSPGASPFTM 234 Query: 290 IHEKHAHTIKPALVGWFGHELSTRFKMDNKLQLIPGVCGFRIS------NPPILLVCSLH 343 R K+ N + + + S PI L +L Sbjct: 235 SSRAIEKL------------QRRRTKVANWYLDMNLLGKYWGSERVYHHTAPINLYYALR 282 Query: 344 ASLEIFKQATMKALRKKSVLLTGYLEYLIK 373 +L + Q + ++ YL ++ Sbjct: 283 EALRLIAQEGLANCWQRHQKNVEYLWERLE 312 >3LVM-A nrPDB Length = 423 Score = 52.8 bits (125), Expect = 3e-07, Method: Composition-based stats. Identities = 44/220 (20%), Positives = 88/220 (40%), Gaps = 17/220 (7%) Query: 118 GLMKDIVGANEKEIALMNALTVNLHLLMLSFFKPTPKRYKILLEAKAFPSDHYAIES--- 174 + D+VGA+ +EI + T + +L + K+ K ++ +K ++H A+ Sbjct: 75 NQIADLVGADPREIVFTSGATESDNLAIKGAANFYQKKGKHIITSK---TEHKAVLDTCR 131 Query: 175 QLQLHGLNIEESMRMIKPREGEETLRIEDILEVIEKEGDSIAVILFSGVHFYTGQHFNIP 234 QL+ G + + + ++++ + D ++ V+ G +I Sbjct: 132 QLEREGFEVTYL-----APQRNGIIDLKELEAAMR---DDTILVSIMHVNNEIGVVQDIA 183 Query: 235 AITKAGQAKGCYVGFDLAHAVGNVELYLHDWGVDFACWCSYKYLNAGAGGIAGAFIHEKH 294 AI + +A+G D +VG + + L VD + +K G GI ++ K Sbjct: 184 AIGEMCRARGIIYHVDATQSVGKLPIDLSQLKVDLMSFSGHKIY--GPKGIGALYVRRKP 241 Query: 295 AHTIKPALVGWFGHELSTRFKMDNKLQLIPGVCGFRISNP 334 I+ + G GHE R Q++ +RI+ Sbjct: 242 RVRIEAQMHGG-GHERGMRSGTLPVHQIVGMGEAYRIAKE 280 >3WKR-A nrPDB Length = 416 Score = 49.7 bits (117), Expect = 3e-06, Method: Composition-based stats. Identities = 53/307 (17%), Positives = 107/307 (34%), Gaps = 52/307 (16%) Query: 125 GANEKEIALMNALTVNLHLLMLSFFKPTPKRYKILLEAKAFPSDHYAIESQLQLHGLNIE 184 GA E + +M+A+ Y +L + + S Y + +L+ + Sbjct: 120 GAREGKFIVMHAIC-------------KEGDYVVLDKNAHYTS--YVAAERAKLNVAEVG 164 Query: 185 ESMRMIKPREGEETLRIEDILEVIEKEGDSIAVILFSGVHFYTGQHFNIPAITKAGQAKG 244 P +++++ +E +G ++ +IL + V G + + K + KG Sbjct: 165 YEEEY--PTYKINLEGYKEVIDNLEDKGKNVGLILLTHVDGEYGNLNDAKKVGKIAKEKG 222 Query: 245 CYVGFDLAHAVGNVELYLHDWGVDFACWCSYKYLNAGAGGIAGAFIHEKHAHTIKPALVG 304 + A+ VG + + + DF +K + A A AF E+ + I Sbjct: 223 IPFLLNCAYTVGRMPVNGKEVKADFIVASGHKSMAASAPCGILAF-SEEFSDKIT----- 276 Query: 305 WFGHELSTRFKMDNKLQLIPGVCGFRISNPPILLVCSLHASLEIFKQATMKALRKKSVLL 364 + S +F + +++++ P + L+ S +E K+ Sbjct: 277 ----KTSEKFPVK-EIEMLGCTSR---GLPIVTLMASFPHVVERVKKWD----------- 317 Query: 365 TGYLEYLIKHNYGKDKAATKKPVVNIITPSHVEERGCQLTITFSVPNKD------VFQEL 418 E L K Y D+ I P + + + + KD + EL Sbjct: 318 ----EELKKTRYVVDELEKIGFKQLGIKPKEHDLIKFETPVLDEIAKKDKRRGFFFYDEL 373 Query: 419 EKRGVVC 425 +KRG+ Sbjct: 374 KKRGIGG 380 >5WT2-A nrPDB Length = 401 Score = 47.4 bits (111), Expect = 1e-05, Method: Composition-based stats. Identities = 45/226 (19%), Positives = 88/226 (38%), Gaps = 16/226 (7%) Query: 69 IYFLGNSLG-LQPKMVKTYLEEELDKWAKIAAYGHEVGKRPWITGDESIVGLMKDIVGAN 127 IY N+ + PK+ + D + ++ H+ G E++ L K I + Sbjct: 5 IYLDNNATTRIDPKVKEIMDPFLRDHYGNPSSL-HQFGTETHPAIAEALDKLYKGINARD 63 Query: 128 EKEIALMN-ALTVNLHLLMLSFFKPTPKRYK--ILLEAKAFPSDHYAIESQLQLHGLNIE 184 ++ + + A N +L +F K+ K I+ P+ + + L+ G+ + Sbjct: 64 IDDVIITSCATESNNWVLKGVYFDECLKKGKNHIVTTVAEHPA-VRSTCNFLESLGVEVT 122 Query: 185 ESMRMIKPREGEETLRIEDILEVIEKEGDSIAVILFSGVHFYTGQHFNIPAITKAGQAKG 244 P ++ E + E I ++ A++ + TG F I I + KG Sbjct: 123 YL-----PINEHGSITAEQVREAITEK---TALVSVMWANNETGLIFPIEEIGAICKEKG 174 Query: 245 CYVGFDLAHAVGNVELYLHDWGVDFACWCSYKYLNAGAGGIAGAFI 290 D A+G + + + DF + ++K+ G GI G +I Sbjct: 175 VLFHTDAVQAIGKIPVDVLKANADFLSFSAHKF--HGPKGIGGLYI 218 >5WGB-A nrPDB Length = 426 Score = 46.3 bits (108), Expect = 3e-05, Method: Composition-based stats. Identities = 63/350 (18%), Positives = 129/350 (36%), Gaps = 53/350 (15%) Query: 78 LQPKMVKTYLEEELDKWAKIAAYGHEVGKRPWITGD--ESIVGLMKDIVGANEKEIALMN 135 L P+++ L ++ + + H G W + E + ++GA+ +EI + Sbjct: 38 LDPRVLDAMLPYLINYYGNPHSRTHAYG---WESEAAMERARQQVASLIGADPREIIFTS 94 Query: 136 --ALTVNLHLLMLSFFKPTPKRYKILLEAKAFPSDHYAIES--QLQLHGLNIEESMRMIK 191 + N+ + ++ F + K++ I + + ++S L+ G + Sbjct: 95 GATESNNIAIKGVARFYRSRKKHLITTQTEH----KCVLDSCRSLEAEGFQVTYL----- 145 Query: 192 PREGEETLRIEDILEVIEKEGDSIAVILFSGVHFYTGQHFNIPAITKAGQAKGCYVGFDL 251 P + + ++++ I+ + ++V+ V+ G I I + ++ Y D Sbjct: 146 PVQKSGIIDLKELEAAIQPDTSLVSVMT---VNNEIGVKQPIAEIGRICSSRKVYFHTDA 202 Query: 252 AHAVGNVELYLHDWGVDFACWCSYKYLNAGAGGIAGAFIHEKHAHTIKPALVGWFGHELS 311 A AVG + L ++D +D +K G G+ +I + ++ G G E Sbjct: 203 AQAVGKIPLDVNDMKIDLMSISGHKIY--GPKGVGAIYIRRRPRVRVEALQSGG-GQER- 258 Query: 312 TRFKMDNKLQLIPGVCGFRISNPPILLVCSLHASLEIFKQATMKALRKKSVLLTGYLEYL 371 G R P LV L A+ E+ Q M+ K+ L+ L Sbjct: 259 ----------------GMRSGTVPTPLVVGLGAACEV-AQQEMEYDHKRISKLSERLIQN 301 Query: 372 IKHNYGKDKAATKKPVVNIITPSHVEERGCQLTITFSVPNKD-VFQELEK 420 I + VV P H GC + ++F+ + + L+ Sbjct: 302 I--------MKSLPDVVMNGDPKHHYP-GC-INLSFAYVEGESLLMALKD 341 >6MRE-A nrPDB Length = 420 Score = 45.9 bits (107), Expect = 3e-05, Method: Composition-based stats. Identities = 48/265 (18%), Positives = 95/265 (35%), Gaps = 29/265 (10%) Query: 46 FYIPKIQDLPPVDLSLVNKDENAIYFLGNSLGLQPKMVKTYLEEELDKWAKIAAYGHEVG 105 F + K++ PV VN A Y + +P + +D A+ +G+ Sbjct: 17 FSVDKVRADFPVLSREVNGLPLA-YLDSAASAQKP-------SQVIDAEAEFYRHGYAAV 68 Query: 106 KRPWITGD-------ESIVGLMKDIVGANEKEIALMNALTVNLHLLMLSFFKPTPKR--- 155 R T E++ + A E + A T L+ + + + R Sbjct: 69 HRGIHTLSAQATEKMENVRKRASLFINARSAEELVFVAGTTEGINLVANSWGNSNVRAGD 128 Query: 156 YKILLEAKAFPSDHYAIESQLQLHGLNIEESMRMIKPREGEETLRIEDILEVIEKEGDSI 215 I+ + +H+A Q+ + +R+I P + TL++E + + +++ + Sbjct: 129 NIIISQM-----EHHANIVPWQMLCARVGAELRVI-PLNPDGTLQLETLPTLFDEKTRLL 182 Query: 216 AVILFSGVHFYTGQHFNIPAITKAGQAKGCYVGFDLAHAVGNVELYLHDWGVDFACWCSY 275 A+ + V G + + G V D A AV + + + DF + + Sbjct: 183 AI---THVSNVLGTENPLAEMITLAHQHGAKVLVDGAQAVMHHPVDVQALDCDFYVFSGH 239 Query: 276 KYLNAGAGGIAGAFIHEKHAHTIKP 300 K G GI ++ E + P Sbjct: 240 KLY--GPTGIGILYVKEALLQEMPP 262 >2BKW-A nrPDB Length = 385 Score = 45.9 bits (107), Expect = 3e-05, Method: Composition-based stats. Identities = 39/202 (19%), Positives = 85/202 (42%), Gaps = 13/202 (6%) Query: 149 FKPTPKRYKILLEAKAFPSDHYAIESQLQLHGLNIEESMRMIKPREGEETLRIEDILEVI 208 P + +++ F SD +A L+ +G ++ +++P + E++ +E I E + Sbjct: 81 LSKAPNKNVLVVSTGTF-SDRFA--DCLRSYGAQVD----VVRPLKIGESVPLELITEKL 133 Query: 209 EKEGDSIAVILFSGVHFYTGQHFNIPAITKAGQAKG--CYVGFDLAHAVGNVELYLHDWG 266 + +S + + V T ++ AI++A + + D ++G E +WG Sbjct: 134 SQ--NSYGAVTVTHVDTSTAVLSDLKAISQAIKQTSPETFFVVDAVCSIGCEEFEFDEWG 191 Query: 267 VDFACWCSYKYLNAGAGGIAGAFIHEKHAH-TIKPALVGWFGHELSTRFKMDNKLQLIPG 325 VDFA S K + G++ + + + + G S+ + ++ Sbjct: 192 VDFALTASQKAI-GAPAGLSISLCSSRFMDYALNDSKNGHVHGYFSSLRRWTPIMENYEA 250 Query: 326 VCGFRISNPPILLVCSLHASLE 347 G + PP+ L+ SL +L+ Sbjct: 251 GKGAYFATPPVQLINSLDVALK 272 >2DR1-A nrPDB Length = 386 Score = 45.9 bits (107), Expect = 4e-05, Method: Composition-based stats. Identities = 49/273 (17%), Positives = 95/273 (34%), Gaps = 29/273 (10%) Query: 194 EGEETLRIEDILEVIEKEGDSIAVILFSGVHFYTGQHFNIPAITKAGQAKGCYVGFDLAH 253 E + ++ ED+ + + K D AV + + TG +P + K + V D Sbjct: 127 EPGKAVKPEDLDDALRKNPDVEAVTI-TYNETSTGVLNPLPELAKVAKEHDKLVFVDAVS 185 Query: 254 AVGNVELYLHDWGVDFACWCSYKYLNAGAGGIAGAFIHEKHAHTIKPALVGW-FGHELST 312 A+G ++ WG+D S K G GAF K GW F L Sbjct: 186 AMGGADIKFDKWGLDVVFSSSQKAFGVPPGLAIGAFSERFLEIAEKMPERGWYFDIPLYV 245 Query: 313 RFKMDNKLQLIPGVCGFRISNPPILLVCSLHASLEIFKQATMKALRKKSVLLTGYLEYLI 372 ++ + + S PP+ V ++ +L I ++ K + Sbjct: 246 KYLKEKESTP---------STPPMPQVFGINVALRIIEKMGGK----------EKWLEMY 286 Query: 373 KHNYGKDKAATKKPVVNIITPSHVEERGCQLTITFSVPNKD-VFQELEKRGV-----VCD 426 + + ++ ++I+ E +T D V++ + KRG Sbjct: 287 EKRAKMVREGVREIGLDILAEPGHESPTITAVLTPPGIKGDEVYEAMRKRGFELAKGYGS 346 Query: 427 KRNPNGIRVAPVPLYNSFHDVYKFTNLLTSILD 459 + R+ + Y F D+ + + L +++ Sbjct: 347 VKE-KTFRIGHMG-YMKFEDIQEMLDNLREVIN 377 >4W91-A nrPDB Length = 422 Score = 43.6 bits (101), Expect = 2e-04, Method: Composition-based stats. Identities = 51/337 (15%), Positives = 116/337 (34%), Gaps = 19/337 (5%) Query: 37 DKLRHFRECFYIPKIQDLPPVDLSLVNKDENAIYFLGNSLGLQPKMVK-TYLEEELDKWA 95 D+ + + I+ P+ LS + +Y + +P+ V +++A Sbjct: 10 DQKNPLTMAYDVEAIRRDFPI-LSRQVHGKTLVYLDNGASAQKPQSVIDAVTHAYANEYA 68 Query: 96 KIAAYGHEVGKRPWITGDESIVGLMKDIVGANEKEIALMNALTVNLHLLMLSFFKP-TPK 154 + H + ++S + + + + EI T ++ + + P + Sbjct: 69 NVHRGLHFLSNAATDAYEKSRETVRRFLNAGSVDEIVFTKNATEAINTVAYGYGMPFIGE 128 Query: 155 RYKILLEAKAFPSDHYAIESQLQLHGLNIEESMRMIKPR-EGEETLRIEDILEVIEKEGD 213 +ILL S+ + H + + +++ + IE+ + + + Sbjct: 129 GDEILLSIMEHHSN------IVPWHFIRERQGAKLVFTPVDDNGVFHIEEFEKRLSE--- 179 Query: 214 SIAVILFSGVHFYTGQHFNIPAITKAGQAKGCYVGFDLAHAVGNVELYLHDWGVDFACWC 273 ++ + + G I I + A+G V D + ++ + + D G D+ + Sbjct: 180 RTKLVAITHMSNTLGTVVPIKKIVELAHARGIPVLVDGSQGAVHLPVDVQDLGCDWYVFT 239 Query: 274 SYKYLNAGAGGIAGAFIHEKHAHTIKPALVGWFGHELSTRFKMDNKLQLIPGVCGFRISN 333 +K G GI + + ++P G G + + + P F Sbjct: 240 GHKVY--GPSGIGVLYGRAQMLEKMRPFQGG--GEMIEEVTEENVTYNHPPH--RFEAGT 293 Query: 334 PPILLVCSLHASLEIFKQATMKALRKKSVLLTGYLEY 370 PPI+ L A+LE ++ A+ L Y Sbjct: 294 PPIVQAIGLGAALEYMEKIGRHAILAHEADLRDYAHE 330 >2YRI-A nrPDB Length = 353 Score = 42.8 bits (99), Expect = 4e-04, Method: Composition-based stats. Identities = 54/270 (20%), Positives = 94/270 (34%), Gaps = 26/270 (9%) Query: 129 KEIALMNALTVNLHLLMLSFFKPTPKRYKILLEAKAFPSDHYAIESQLQLHGLNIEESMR 188 E AL+ AL + L M + + ++L AF + LHGL+ E Sbjct: 49 GEGALVAALAGSGSLGMEAGLANLDRGPVLVLVNGAFSQR---VAEMAALHGLDPE---- 101 Query: 189 MIKPREGEETLRIEDILEVIEK--EGDSIAVILFSGVHFYTGQHFNIPAITKAGQAKGCY 246 ++ GE E + + + ++ TG AI + G Sbjct: 102 VLDFPPGEPVD-----PEAVARALKRRRYRMVALVHGETSTGVLNPAEAIGALAKEAGAL 156 Query: 247 VGFDLAHAVGNVELYLHDWGVDFACWCSYKYLNAGAG-GIAGAFIHEKHAHTIKPALVGW 305 D +G + + GVD+A S K L+A G A + + A T K GW Sbjct: 157 FFLDAVTTLGMLPFSMRAMGVDYAFTGSQKCLSAPPGLAPIAASLEARKAFTGKR---GW 213 Query: 306 FGHELSTRFKMDNKLQLIPGVCGFRISNPPILLVCSLHASLEIFKQATMKALRKKSVLLT 365 + +L+ + + G+ + P +L L A + ++ R+ + Sbjct: 214 Y-LDLARVAEHWER-------GGYHHTTPVLLHYALLEALDLVLEEGVAARERRAREVYA 265 Query: 366 GYLEYLIKHNYGKDKAATKKPVVNIITPSH 395 LE L + A+ P V ++ P Sbjct: 266 WVLEELKARGFRPYPKASPLPTVLVVRPPE 295 >1M32-A nrPDB Length = 366 Score = 39.7 bits (91), Expect = 0.002, Method: Composition-based stats. Identities = 35/252 (13%), Positives = 84/252 (33%), Gaps = 26/252 (10%) Query: 114 ESIVGLMKDIVGANEK--EIALMNALTVNLHLLMLSFFKPTPKRYKILLEAKAFPSDHYA 171 E I + + A+E + L + + + ++ S P+ +++ A+ + Sbjct: 40 EQIRQQLTALATASEGYTSVLLQGSGSYAVEAVLGSAL--GPQDKVLIVSNGAYGARMVE 97 Query: 172 IESQLQL--HGLNIEESMRMIKPREGEETLRIEDILEVIEKEGDSIAVILFSGVHFYTGQ 229 + + + H + E R ++ I +I+ I TG Sbjct: 98 MAGLMGIAHHAYDCGEVAR-----------PDVQAIDAILNADPTISHIAMVHSETTTGM 146 Query: 230 HFNIPAITKAGQAKGCYVGFDLAHAVGNVELYLHDWGVDFACWCSYKYLNAGAGGIAGAF 289 I + G D + G + + + +D+ + K + G AF Sbjct: 147 LNPIDEVGALAHRYGKTYIVDAMSSFGGIPMDIAALHIDYLISSANKCIQGVPG---FAF 203 Query: 290 IHEKHAHTIKPALVGWFGHELSTRFKMDNKLQ-LIPGVCGFRISNPPILLVCSLHASLEI 348 + + + L GH S + + + + +R ++P ++ A E+ Sbjct: 204 VIAR-----EQKLAACKGHSRSLSLDLYAQWRCMEDNHGKWRFTSPTHTVLAFAQALKEL 258 Query: 349 FKQATMKALRKK 360 K+ + A ++ Sbjct: 259 AKEGGVAARHQR 270 >3KGX-A nrPDB Length = 393 Score = 39.7 bits (91), Expect = 0.003, Method: Composition-based stats. Identities = 21/96 (21%), Positives = 37/96 (38%), Gaps = 4/96 (4%) Query: 188 RMIKPREGEETLRIEDILEVIEKEGDSIAVILFSGVHFYTGQHFNIPAITKAGQAKGCYV 247 +MIK TL +++ E + + ++ TG + + C + Sbjct: 126 QMIKKPGEHYTL--QEVEEGLAQHKP--VLLFLVHGESSTGVVQPLDGFGELCHRYQCLL 181 Query: 248 GFDLAHAVGNVELYLHDWGVDFACWCSYKYLNAGAG 283 D ++G V +Y+ G+D S K LNA G Sbjct: 182 LVDSVASLGGVPIYMDQQGIDIMYSSSQKVLNAPPG 217 >2CH1-A nrPDB Length = 396 Score = 38.2 bits (87), Expect = 0.008, Method: Composition-based stats. Identities = 18/116 (15%), Positives = 38/116 (32%), Gaps = 4/116 (3%) Query: 184 EESMRMIKPREGEETLRIEDILEVIEKEGDSIAVILFSGVHFYTGQHFNIPAITKAGQAK 243 +R I+ + +E + IE + + +G + + + Sbjct: 116 GADVRTIEGP-PDRPFSLETLARAIELHQPK--CLFLTHGDSSSGLLQPLEGVGQICHQH 172 Query: 244 GCYVGFDLAHAVGNVELYLHDWGVDFACWCSYKYLNAGAGGIAGAFIHEKHAHTIK 299 C + D ++ V Y+ W +D A + + + GI I K I+ Sbjct: 173 DCLLIVDAVASLCGVPFYMDKWEID-AVYTGAQKVLGAPPGITPISISPKALDVIR 227 >5LUC-A nrPDB Length = 403 Score = 37.4 bits (85), Expect = 0.014, Method: Composition-based stats. Identities = 42/224 (18%), Positives = 79/224 (35%), Gaps = 29/224 (12%) Query: 189 MIKPREGEETLRIEDILEVIEKEGDSIAVILFSGVHFYTGQHFNIPAITKAGQAKGCYVG 248 M K G TL +++ E + + ++ + TG + + C + Sbjct: 137 MTKDPGGHYTL--QEVEEGLAQHKP--VLLFLTHGESSTGVLQPLDGFGELCHRYKCLLL 192 Query: 249 FDLAHAVGNVELYLHDWGVDFACWCSYKYLNAGAGGIAGAFIHEKHAHTIKPALVGWFGH 308 + ++G LY+ G+D S K LNA G +F + K + Sbjct: 193 VNSVASLGGTPLYMDRQGIDILYSGSQKALNAPPGTSLISF-----SDKAKKKM------ 241 Query: 309 ELSTRFKMDNKLQLIPGVCGFR-ISNP--------PILLVCSLHASLEIFKQATM----K 355 S + K + I + F + P++ + SL SL + + + + Sbjct: 242 -YSRKTKPFSFYLDIKWLANFWGCDDQPRMYHHTIPVISLYSLRESLALIAEQGLENSWR 300 Query: 356 ALRKKSVLLTGYLEYLIKHNYGKDKAATKKPVVNIITPSHVEER 399 R+ + L G L+ L + KD A V + P+ + R Sbjct: 301 QHREAAAYLHGRLQALGLQLFVKDPALRLPTVTTVAVPAGYDWR 344 >4WJB-A nrPDB Length = 424 Score = 35.5 bits (80), Expect = 0.048, Method: Composition-based stats. Identities = 15/78 (19%), Positives = 29/78 (37%), Gaps = 3/78 (3%) Query: 345 SLEIFKQATMKALRKKSVLLTGYLEYLIK---HNYGKDKAATKKPVVNIITPSHVEERGC 401 ++ T A R+ +++ + ++ Y D AT + + GC Sbjct: 235 GVDAHAGTTPMAFRRDALVGAARMISFVEVLGRRYAPDARATVGMIEARPNSRNTVPGGC 294 Query: 402 QLTITFSVPNKDVFQELE 419 T+ F P+ V EL+ Sbjct: 295 FFTVEFRHPDDAVLDELD 312 >3CAI-A nrPDB Length = 406 Score = 35.1 bits (79), Expect = 0.060, Method: Composition-based stats. Identities = 58/370 (15%), Positives = 109/370 (29%), Gaps = 45/370 (12%) Query: 66 ENAIYFLGNSLGLQPKMVKTYLEEELDKWAKIAAYGHEVGKRPWITGDESIVGLMKDIVG 125 + ++F + L P V T + + H +R D + + D+V Sbjct: 25 DGWVHFDAPAGMLIPDSVATTVSTAFRRSGASTVGAHPSARRSAAVLDAA-REAVADLVN 83 Query: 126 ANEKEIALMNALTVNLHLLMLSFFKPTPKRYKILLEAKAFPSDHYAIESQLQLHGLNIEE 185 A+ + L V L LL + Y++++ + H + Sbjct: 84 ADPGGVVLGADRAVLLSLLAEASSSRAGLGYEVIV--SRLDDEANIAPWLRAAHRYGAKV 141 Query: 186 SMRMIKPREGEETLRIEDILEVIEKEGDSIAVILFSGVHFYTGQHFNIPAITKAGQAKGC 245 + GE + L I K +AV SG G ++ A+TK G Sbjct: 142 KWAEVDIETGELPTWQWESL--ISKSTRLVAVNSASGT---LGGVTDLRAMTKLVHDVGA 196 Query: 246 YVGFDLAHAVGNVELYLHDWGVDFACWCSYKYLNAGAGGIAGAFIHEKHAHTIKPALVGW 305 V D + A L + + D ++ + G A F ++ Sbjct: 197 LVVVDHSAAAPYRLLDIRETDADVVTVNAHAW--GGPPIGAMVFRDPSVMNS-------- 246 Query: 306 FGHELSTRFKMDNKLQLIPGVCGFRISNPPILLVCSLHASLEIFKQATMKAL--RKKSVL 363 FG + + I L+ + AS+E A R++ + Sbjct: 247 FGSVSTNPYATGP--------ARLEIGVHQFGLLAGVVASIEYLAALDESARGSRRERLA 298 Query: 364 ---------LTGYLEYLIKHNYGKDKAATKKPVVNIITPSHVEERGCQLTITFSVPNKDV 414 L +YL+ + + + ++ + VP V Sbjct: 299 VSMQSADAYLNRVFDYLM--------VSLRSLPLVMLIGRPEAQIPVVSFAVHKVPADRV 350 Query: 415 FQELEKRGVV 424 Q L G++ Sbjct: 351 VQRLADNGIL 360 >4ISY-A nrPDB Length = 404 Score = 34.7 bits (78), Expect = 0.095, Method: Composition-based stats. Identities = 32/231 (13%), Positives = 76/231 (32%), Gaps = 14/231 (6%) Query: 60 SLVNKDENAIYFLGNSLGLQPKMVKTYLEEELDKWAKIAAYGHEVGKRPWITGDESIVGL 119 S + + Y + + ++ H G+ +E+ L Sbjct: 4 SHHHHHHGSAYLDHAATTPMHPAAIEAMAAVQRTIGNASSL-HTSGRSARRRIEEA-REL 61 Query: 120 MKDIVGANEKEIALM--NALTVNLHLLMLSFFKP--TPKRYKILLEAKAFPSDHYAIESQ 175 + D +GA E+ + NL + + + + P R +I+ + ++ Sbjct: 62 IADKLGARPSEVIFTAGGTESDNLAVKGIYWARRDAEPHRRRIVTTEVEHHAVLDSVNWL 121 Query: 176 LQLHGLNIEESMRMIKPREGEETLRIEDILEVIEKEGDSIAVILFSGVHFYTGQHFNIPA 235 ++ G ++ P + ++ + E + + D +A++ + G I Sbjct: 122 VEHEGAHVTWL-----PTAADGSVSATALREAL-QSHDDVALVSVMWANNEVGTILPIAE 175 Query: 236 ITKAGQAKGCYVGFDLAHAVGNVELYLHDWGVDFACWCSYKYLNAGAGGIA 286 ++ G + D AVG + L G+ +K+ G G+ Sbjct: 176 MSVVAMEFGVPMHSDAIQAVGQLPLDFGASGLSAMSVAGHKF--GGPPGVG 224 >4EB7-A nrPDB Length = 382 Score = 34.3 bits (77), Expect = 0.11, Method: Composition-based stats. Identities = 48/264 (18%), Positives = 87/264 (32%), Gaps = 27/264 (10%) Query: 70 YFLGNSLGLQPK---MVKTYLEEELDKWAKIAAYGHEVGKRPWITGDESIVGLMKDIVGA 126 YF S +P +++ L + + ++ H G + + + +V Sbjct: 3 YFDYTS--AKPVDERILEAMLPYMTESFGNPSS-VHSYGFKA-REAVQEAREKVAKLVNG 58 Query: 127 NEKEIALMN-ALTVNLHLLMLSFFKPTPKRYKILLEAKAFPSDHYAIESQLQLHGLNIEE 185 + + A N ++ + K IL+ A S + LQ G +E Sbjct: 59 GGGTVVFTSGATEANNLAIIGYAMRNARKGKHILVSAVEHMSVINPAK-FLQKQGFEVEY 117 Query: 186 SMRMIKPREGEETLRIEDILEVIEKEGDSIAVILFSGVHFYTGQHFNIPAITKAGQAKGC 245 + + GE + D +K D ++ + G + I++ K Sbjct: 118 ---IPVGKYGEVDVSFID-----QKLRDDTILVSVQHANNEIGTIQPVEEISEVLAGKAA 169 Query: 246 YVGFDLAHAVGNVELYLHDWGVDFACWCSYKYLNAGAGGIAGAFIHEKHAHTIKPALVGW 305 D +VG +E+ + G D S G G+ +I K A L G Sbjct: 170 LHI-DATASVGQIEVDVEKIGADMLTISSNDIY--GPKGVGALWIR-KEAKLQPVILGG- 224 Query: 306 FGHELSTRFKMDNKLQLIPGVCGF 329 G E R +N +P + GF Sbjct: 225 -GQENGLRSGSEN----VPSIVGF 243 >4MY5-A nrPDB Length = 393 Score = 33.5 bits (75), Expect = 0.20, Method: Composition-based stats. Identities = 30/128 (23%), Positives = 52/128 (40%), Gaps = 11/128 (8%) Query: 128 EKEIALMNALTVNLHLLMLSFFKPTPKRYKILLEAKAFPSDHYAIESQLQLHGLNIEESM 187 + EI + T L + + +P K +LL A A+P E + L G + E Sbjct: 93 DNEILVTIGATEALSASLTAILEPGDK---VLLPAPAYPG----YEPVVNLVGAEVVE-- 143 Query: 188 RMIKPREGEETLRIEDILEVIEKEGDSIAVILFSGVHFYTGQHFNIPAITKAGQAKGCYV 247 I R + L E + E I KEG+++ ++ + TG ++ I + Y Sbjct: 144 --IDTRSNDFVLTPEMLEEAILKEGEALKAVILNYPTNPTGVTYSRQQIKNLAEVLKKYP 201 Query: 248 GFDLAHAV 255 F ++ V Sbjct: 202 IFVISDEV 209 >4BF9-A nrPDB Length = 338 Score = 32.8 bits (73), Expect = 0.37, Method: Composition-based stats. Identities = 15/41 (36%), Positives = 19/41 (46%), Gaps = 2/41 (4%) Query: 244 GCYVGFDLAHAVGNVELYLHDWGVDFACWCSYKYLNAGAGG 284 G + + +A VE L WGVD C C K +N GG Sbjct: 94 GQFPQWLAENAARAVE--LGSWGVDLNCGCPSKTVNGSGGG 132 >2DKJ-A nrPDB Length = 407 Score = 30.8 bits (68), Expect = 1.1, Method: Composition-based stats. Identities = 15/57 (26%), Positives = 24/57 (42%), Gaps = 3/57 (5%) Query: 232 NIPAITKAGQAKGCYVGFDLAHAVGNVELYLHDWGVDFA---CWCSYKYLNAGAGGI 285 + A + G Y+ D+AH G V LH + +A ++K L GG+ Sbjct: 179 DFKAFREIADEVGAYLVVDMAHFAGLVAAGLHPNPLPYAHVVTSTTHKTLRGPRGGL 235 >4FUU-A nrPDB Length = 309 Score = 30.8 bits (68), Expect = 1.2, Method: Composition-based stats. Identities = 15/69 (21%), Positives = 24/69 (34%), Gaps = 5/69 (7%) Query: 61 LVNKDENAIYFLGNSLGLQPKMVKTYLEEELDKWAKIAAYGHEVGKRPWITGDESIVGLM 120 + N+ + I + G L + + E + K A RPW D Sbjct: 65 VTNQYADLIAYDGTLLKARNIIGSYKPESK-----KRIALFAHWDTRPWADNDADEKNHH 119 Query: 121 KDIVGANEK 129 I+GAN+ Sbjct: 120 TPILGANDG 128 >3NZW-E nrPDB Length = 234 Score = 30.8 bits (68), Expect = 1.2, Method: Composition-based stats. Identities = 15/50 (30%), Positives = 23/50 (46%) Query: 67 NAIYFLGNSLGLQPKMVKTYLEEELDKWAKIAAYGHEVGKRPWITGDESI 116 N G ++G + + KTYLE LD + KI E+ K +S+ Sbjct: 152 NVTELYGTAIGARSQGAKTYLERTLDTFIKIDGNPDELIKAGVEAISQSL 201 >4P3M-A nrPDB Length = 429 Score = 30.1 bits (66), Expect = 1.9, Method: Composition-based stats. Identities = 45/241 (18%), Positives = 86/241 (35%), Gaps = 27/241 (11%) Query: 62 VNKDENAIYFLGNSLGLQPKMVKTYLEEELDKWAKIAAYGHEVGKRPWITGDESI-VGLM 120 V + E+ I + + P++++ + +K+A+ G ++ ES+ + Sbjct: 23 VQRQEDHIELIASENYTSPRVMEAQGSQLTNKYAEGYPGKRYYGGCEYVDVAESLAIERA 82 Query: 121 KDIVGANEKEIALMNALTVNLHLLMLSFFKPTPKRYKILLEAKAFPSDHYAIESQLQ--- 177 K + GA+ + + N + +A P D S Sbjct: 83 KSLFGADYANVQPHSGSQAN----------------AAVYQALCAPGDTILGMSLAHGGH 126 Query: 178 -LHGLNIEESMRMIKPREGEETLR--IEDILEVIEKEGDSIAVILFSGVHFYTGQHFNIP 234 HG ++ S +M + T I D E+ + ++ +G Y+G + Sbjct: 127 LTHGSHVSFSGKMYNAVQYGITPETGILDYAEIERLAVEHKPTMIIAGFSAYSG-IVDWA 185 Query: 235 AITKAGQAKGCYVGFDLAHAVGNVELYLHDWGVDFA---CWCSYKYLNAGAGGIAGAFIH 291 + G Y+ D+AH G V L+ V FA ++K L GG+ A + Sbjct: 186 KFREIADKVGAYLFVDMAHVAGLVAAGLYPNPVPFADVVTTTTHKTLGGPRGGLILAKAN 245 Query: 292 E 292 E Sbjct: 246 E 246 >3DHU-A nrPDB Length = 449 Score = 30.1 bits (66), Expect = 2.0, Method: Composition-based stats. Identities = 33/168 (19%), Positives = 56/168 (33%), Gaps = 19/168 (11%) Query: 212 GDSIAVILFSGVHFYTGQHFNIPAITKAGQAKGCYVGFDLAHAVGNVELYLHDWGVDFAC 271 G A+ + G++ G + A+T G V D+ + + + L + Sbjct: 65 GSPYAIKDYRGINPEYGTLADFKALTDRAHELGMKVMLDIVYNHTSPDSVL---ATEHPE 121 Query: 272 WCSYKYLNAGAGGIAGAFIHEKHAHTIKPALVGWFGHELSTRFKMDNKLQLIPGVCGFRI 331 W Y + G + K +GH ++++D L V G+R Sbjct: 122 W-FYHDADGQLTNKVGDWSDVKDLD---------YGHHELWQYQIDTLLYWSQFVDGYRC 171 Query: 332 SNPPILLVCSLHASLEIFKQATMK---ALRKKSVLLTGYLEYLIKHNY 376 P + L LE KQ K L +G++E L Y Sbjct: 172 DVAP---LVPLDFWLEARKQVNAKYPETLWLAESAGSGFIEELRSQGY 216 >1TY8-A nrPDB Length = 284 Score = 29.7 bits (65), Expect = 2.8, Method: Composition-based stats. Identities = 15/52 (28%), Positives = 27/52 (51%) Query: 322 LIPGVCGFRISNPPILLVCSLHASLEIFKQATMKALRKKSVLLTGYLEYLIK 373 +IPG+C PPI+ S+ +L ++ + K+VL+ YL+Y + Sbjct: 189 IIPGLCTGYAGVPPIISCKSMAFALRLYMAGDHISKELKNVLIMYYLQYPFE 240 >4OTL-A nrPDB Length = 423 Score = 29.3 bits (64), Expect = 3.8, Method: Composition-based stats. Identities = 13/57 (22%), Positives = 25/57 (43%), Gaps = 3/57 (5%) Query: 232 NIPAITKAGQAKGCYVGFDLAHAVGNVELYLHD---WGVDFACWCSYKYLNAGAGGI 285 + + K ++ G Y+ D+AH G + ++ DF ++K L GG+ Sbjct: 191 DFERLAKIAKSVGAYLMVDMAHYAGLIAAGVYPNPVPHADFVTTTTHKSLRGPRGGV 247 >1YJS-A nrPDB Length = 419 Score = 28.9 bits (63), Expect = 5.2, Method: Composition-based stats. Identities = 18/74 (24%), Positives = 29/74 (39%), Gaps = 5/74 (6%) Query: 232 NIPAITKAGQAKGCYVGFDLAHAVGNVELYLHDWGVDFA---CWCSYKYLNAGAGGIAGA 288 + + G Y+ D+AH G V LH V +A +++ L GG+ Sbjct: 179 DFAKFREIADEVGAYLMVDMAHIAGLVAAGLHPNPVPYAHFVTTTTHQTLRGPRGGM--I 236 Query: 289 FIHEKHAHTIKPAL 302 E+ A I A+ Sbjct: 237 LCQEQFAKQIDKAI 250 >6HEG-A nrPDB Length = 809 Score = 28.5 bits (62), Expect = 6.8, Method: Composition-based stats. Identities = 12/42 (28%), Positives = 18/42 (42%) Query: 292 EKHAHTIKPALVGWFGHELSTRFKMDNKLQLIPGVCGFRISN 333 E + I P L G F ++ R D + QL G+ +N Sbjct: 482 EADSSLIAPLLAGAFADRIARRRGQDGRYQLANGMGAMLDAN 523 >1E5R-A nrPDB Length = 290 Score = 28.1 bits (61), Expect = 8.8, Method: Composition-based stats. Identities = 26/111 (23%), Positives = 42/111 (37%), Gaps = 8/111 (7%) Query: 122 DIVGANEKEIALMNALTVNLHLLMLSFFKPTPKRYKILLEAKAF--PSDHYAIESQLQLH 179 ++ EI ++A TV+ S + + L AF P D I + L+ Sbjct: 140 TVIHMRPGEIWFLDAATVH------SAVNFSEISRQSLCVDFAFDGPFDEKEIFADATLY 193 Query: 180 GLNIEESMRMIKPREGEETLRIEDILEVIEKEGDSIAVILFSGVHFYTGQH 230 + +P E RI + +VIE+E + L S VH+ H Sbjct: 194 APGSTPDLPERRPFTAEHRRRILSLGQVIERENFRDILFLLSKVHYKYDVH 244 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.315 0.130 0.356 Lambda K H 0.267 0.0399 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 17,613,852 Number of Sequences: 36641 Number of extensions: 709208 Number of successful extensions: 1921 Number of sequences better than 10.0: 35 Number of HSP's better than 10.0 without gapping: 28 Number of HSP's successfully gapped in prelim test: 24 Number of HSP's that attempted gapping in prelim test: 1875 Number of HSP's gapped (non-prelim): 53 length of query: 465 length of database: 10,336,785 effective HSP length: 101 effective length of query: 364 effective length of database: 6,636,044 effective search space: 2415520016 effective search space used: 2415520016 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 61 (28.1 bits)