BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q16654 (411 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 2E0A-A nrPDB 819 0.0 2Q8F-A nrPDB 577 e-165 3CRK-A nrPDB 573 e-164 1Y8N-A nrPDB 543 e-155 4DZY-A nrPDB 159 3e-39 3SL2-A nrPDB 44 2e-04 5LFK-A nrPDB 39 0.004 6AZR-A nrPDB 38 0.009 4I5S-A nrPDB 38 0.010 5CPH-A nrPDB 35 0.063 4GCZ-A nrPDB 35 0.069 4URM-A nrPDB 35 0.071 1PVG-A nrPDB 31 0.84 2DGN-A nrPDB 30 1.8 4PL9-A nrPDB 30 1.9 1SQG-A nrPDB 30 2.1 4PU9-A nrPDB 29 4.3 4ZI9-A nrPDB 29 4.4 4XEM-A nrPDB 29 4.4 5SZL-A nrPDB 28 4.9 5MMP-A nrPDB 28 5.5 3EJX-A nrPDB 28 6.3 3VNK-A nrPDB 28 9.5 5IDJ-A nrPDB 28 9.6 >2E0A-A nrPDB Length = 394 Score = 819 bits (2116), Expect = 0.0, Method: Compositional matrix adjust. Identities = 393/394 (99%), Positives = 393/394 (99%) Query: 18 GLVPREVEHFSRYSPSPLSMKQLLDFGSENACERTSFAFLRQELPVRLANILKEIDILPT 77 G VPREVEHFSRYSPSPLSMKQLLDFGSENACERTSFAFLRQELPVRLANILKEIDILPT Sbjct: 1 GPVPREVEHFSRYSPSPLSMKQLLDFGSENACERTSFAFLRQELPVRLANILKEIDILPT 60 Query: 78 QLVNTSSVQLVKSWYIQSLMDLVEFHEKSPDDQKALSDFVDTLIKVRNRHHNVVPTMAQG 137 QLVNTSSVQLVKSWYIQSLMDLVEFHEKSPDDQKALSDFVDTLIKVRNRHHNVVPTMAQG Sbjct: 61 QLVNTSSVQLVKSWYIQSLMDLVEFHEKSPDDQKALSDFVDTLIKVRNRHHNVVPTMAQG 120 Query: 138 IIEYKDACTVDPVTNQNLQYFLDRFYMNRISTRMLMNQHILIFSDSQTGNPSHIGSIDPN 197 IIEYKDACTVDPVTNQNLQYFLDRFYMNRISTRMLMNQHILIFSDSQTGNPSHIGSIDPN Sbjct: 121 IIEYKDACTVDPVTNQNLQYFLDRFYMNRISTRMLMNQHILIFSDSQTGNPSHIGSIDPN 180 Query: 198 CDVVAVVQDAFECSRMLCDQYYLSSPELKLTQVNGKFPDQPIHIVYVPSHLHHMLFELFK 257 CDVVAVVQDAFECSRMLCDQYYLSSPELKLTQVNGKFPDQPIHIVYVPSHLHHMLFELFK Sbjct: 181 CDVVAVVQDAFECSRMLCDQYYLSSPELKLTQVNGKFPDQPIHIVYVPSHLHHMLFELFK 240 Query: 258 NAMRATVEHQENQPSLTPIEVIVVLGKEDLTIKISDRGGGVPLRIIDRLFSYTYSTAPTP 317 NAMRATVEHQENQPSLTPIEVIVVLGKEDLTIKISDRGGGVPLRIIDRLFSYTYSTAPTP Sbjct: 241 NAMRATVEHQENQPSLTPIEVIVVLGKEDLTIKISDRGGGVPLRIIDRLFSYTYSTAPTP 300 Query: 318 VMDNSRNAPLAGFGYGLPISRLYAKYFQGDLNLYSLSGYGTDAIIYLKALSSESIEKLPV 377 VMDNSRNAPLAGFGYGLPISRLYAKYFQGDLNLYSLSGYGTDAIIYLKALSSESIEKLPV Sbjct: 301 VMDNSRNAPLAGFGYGLPISRLYAKYFQGDLNLYSLSGYGTDAIIYLKALSSESIEKLPV 360 Query: 378 FNKSAFKHYQMSSEADDWCIPSREPKNLAKEVAM 411 FNKSAFKHYQMSSEADDWCIPSREPKNLAKEVAM Sbjct: 361 FNKSAFKHYQMSSEADDWCIPSREPKNLAKEVAM 394 >2Q8F-A nrPDB Length = 407 Score = 577 bits (1486), Expect = e-165, Method: Compositional matrix adjust. Identities = 263/390 (67%), Positives = 330/390 (84%), Gaps = 3/390 (0%) Query: 20 VPREVEHFSRYSPSPLSMKQLLDFGSENACERTSFAFLRQELPVRLANILKEIDILPTQL 79 VP +V+ ++R+SPSPLSMKQ LDFGS NACE+TSF FLRQELPVRLANI+KEI +LP L Sbjct: 13 VPGQVDFYARFSPSPLSMKQFLDFGSVNACEKTSFMFLRQELPVRLANIMKEISLLPDNL 72 Query: 80 VNTSSVQLVKSWYIQSLMDLVEFHEKSPDDQKALSDFVDTLIKVRNRHHNVVPTMAQGII 139 + T SVQLV+SWYIQSL +L++F +KS +D KA+ DF DT+I++RNRH++V+PTMAQG+I Sbjct: 73 LRTPSVQLVQSWYIQSLQELLDFKDKSAEDAKAIYDFTDTVIRIRNRHNDVIPTMAQGVI 132 Query: 140 EYKDACTVDPVTNQNLQYFLDRFYMNRISTRMLMNQHILIFSDSQTGNPSH---IGSIDP 196 EYK++ VDPVT+QN+QYFLDRFYM+RIS RML+NQH L+F G+PSH IGSI+P Sbjct: 133 EYKESFGVDPVTSQNVQYFLDRFYMSRISIRMLLNQHSLLFGGKGKGSPSHRKHIGSINP 192 Query: 197 NCDVVAVVQDAFECSRMLCDQYYLSSPELKLTQVNGKFPDQPIHIVYVPSHLHHMLFELF 256 NC+V+ V++D +E +R LCD YY++SPEL+L ++N K P QPI +VYVPSHL+HM+FELF Sbjct: 193 NCNVLEVIKDGYENARRLCDLYYINSPELELEELNAKSPGQPIQVVYVPSHLYHMVFELF 252 Query: 257 KNAMRATVEHQENQPSLTPIEVIVVLGKEDLTIKISDRGGGVPLRIIDRLFSYTYSTAPT 316 KNAMRAT+EH N+ PI+V V LG EDLT+K+SDRGGGVPLR IDRLF+Y YSTAP Sbjct: 253 KNAMRATMEHHANRGVYPPIQVHVTLGNEDLTVKMSDRGGGVPLRKIDRLFNYMYSTAPR 312 Query: 317 PVMDNSRNAPLAGFGYGLPISRLYAKYFQGDLNLYSLSGYGTDAIIYLKALSSESIEKLP 376 P ++ SR PLAGFGYGLPISRLYA+YFQGDL LYSL GYGTDA+IY+KALS++SIE+LP Sbjct: 313 PRVETSRAVPLAGFGYGLPISRLYAQYFQGDLKLYSLEGYGTDAVIYIKALSTDSIERLP 372 Query: 377 VFNKSAFKHYQMSSEADDWCIPSREPKNLA 406 V+NK+A+KHY + EADDWC+PSREPK++ Sbjct: 373 VYNKAAWKHYNTNHEADDWCVPSREPKDMT 402 >3CRK-A nrPDB Length = 407 Score = 573 bits (1477), Expect = e-164, Method: Compositional matrix adjust. Identities = 265/405 (65%), Positives = 338/405 (83%), Gaps = 6/405 (1%) Query: 1 MKAARFVLRSAGSLNGAGLVPREVEHFSRYSPSPLSMKQLLDFGSENACERTSFAFLRQE 60 M+ R +L++A SL GA P+ +EHFS++SPSPLSMKQ LDFGS NACE+TSF FLRQE Sbjct: 1 MRWFRALLKNA-SLAGA---PKYIEHFSKFSPSPLSMKQFLDFGSSNACEKTSFTFLRQE 56 Query: 61 LPVRLANILKEIDILPTQLVNTSSVQLVKSWYIQSLMDLVEFHEKSPDDQKALSDFVDTL 120 LPVRLANI+KEI++LP ++++T SVQLV+SWY+QSL+D++EF +K P+D + LS F D L Sbjct: 57 LPVRLANIMKEINLLPDRVLSTPSVQLVQSWYVQSLLDIMEFLDKDPEDHRTLSQFTDAL 116 Query: 121 IKVRNRHHNVVPTMAQGIIEYKDACTVDPVTNQNLQYFLDRFYMNRISTRMLMNQHILIF 180 + +RNRH++VVPTMAQG++EYKD DPV+NQN+QYFLDRFY++RIS RML+NQH LIF Sbjct: 117 VTIRNRHNDVVPTMAQGVLEYKDTYGDDPVSNQNIQYFLDRFYLSRISIRMLINQHTLIF 176 Query: 181 SDSQT-GNPSHIGSIDPNCDVVAVVQDAFECSRMLCDQYYLSSPELKLTQVNGKFPDQPI 239 S +P HIGSIDPNC V VV+DA++ +++LCD+YY++SP+L++ +VN QPI Sbjct: 177 DGSTNPAHPKHIGSIDPNCSVSDVVKDAYDMAKLLCDKYYMASPDLEIQEVNATNATQPI 236 Query: 240 HIVYVPSHLHHMLFELFKNAMRATVEHQENQPSLTPIEVIVVLGKEDLTIKISDRGGGVP 299 H+VYVPSHL+HMLFELFKNAMRATVE E+ +L PI+++V LG+EDL+IK+SDRGGGVP Sbjct: 237 HMVYVPSHLYHMLFELFKNAMRATVESHESSLTLPPIKIMVALGEEDLSIKMSDRGGGVP 296 Query: 300 LRIIDRLFSYTYSTAPTPVMDNSRNAPLAGFGYGLPISRLYAKYFQGDLNLYSLSGYGTD 359 LR I+RLFSY YSTAPTP + PLAGFGYGLPISRLYAKYFQGDL L+S+ G+GTD Sbjct: 297 LRKIERLFSYMYSTAPTP-QPGTGGTPLAGFGYGLPISRLYAKYFQGDLQLFSMEGFGTD 355 Query: 360 AIIYLKALSSESIEKLPVFNKSAFKHYQMSSEADDWCIPSREPKN 404 A+IYLKALS++S+E+LPV+NKSA++HYQ EA DWC+PS EPKN Sbjct: 356 AVIYLKALSTDSVERLPVYNKSAWRHYQTIQEAGDWCVPSTEPKN 400 >1Y8N-A nrPDB Length = 419 Score = 543 bits (1398), Expect = e-155, Method: Compositional matrix adjust. Identities = 251/399 (62%), Positives = 321/399 (80%), Gaps = 2/399 (0%) Query: 14 LNGAGLVPREVEHFSRYSPSPLSMKQLLDFGSENACERTSFAFLRQELPVRLANILKEID 73 G VP+++E +SR+SPSPLS+KQ LDFG +NACE+TS+ FLR+ELPVRLAN ++E++ Sbjct: 19 FQGKQPVPKQIERYSRFSPSPLSIKQFLDFGRDNACEKTSYMFLRKELPVRLANTMREVN 78 Query: 74 ILPTQLVNTSSVQLVKSWYIQSLMDLVEFHEKSPDDQKALSDFVDTLIKVRNRHHNVVPT 133 +LP L+N SV LV+SWY+QS ++L+E+ KSP+D + L +F+ LIKVRNRH++VVPT Sbjct: 79 LLPDNLLNRPSVGLVQSWYMQSFLELLEYENKSPEDPQVLDNFLQVLIKVRNRHNDVVPT 138 Query: 134 MAQGIIEYKDACTVDPVTNQNLQYFLDRFYMNRISTRMLMNQHILIF-SDSQTGNPSHIG 192 MAQG+IEYK+ DP + N+QYFLDRFY NRIS RML+NQH L+F D+ +P HIG Sbjct: 139 MAQGVIEYKEKFGFDPFISTNIQYFLDRFYTNRISFRMLINQHTLLFGGDTNPVHPKHIG 198 Query: 193 SIDPNCDVVAVVQDAFECSRMLCDQYYLSSPELKLTQVNGKFPDQPIHIVYVPSHLHHML 252 SIDP C+V VV+DA+E ++MLC+QYYL +PEL++ + N K PD+PI +VYVPSHL HML Sbjct: 199 SIDPTCNVADVVKDAYETAKMLCEQYYLVAPELEVEEFNAKAPDKPIQVVYVPSHLFHML 258 Query: 253 FELFKNAMRATVEHQENQPSLTP-IEVIVVLGKEDLTIKISDRGGGVPLRIIDRLFSYTY 311 FELFKN+MRATVE E++ P ++ +V LGKEDL+IKISD GGGVPLR IDRLF+Y Y Sbjct: 259 FELFKNSMRATVELYEDRKEGYPAVKTLVTLGKEDLSIKISDLGGGVPLRKIDRLFNYMY 318 Query: 312 STAPTPVMDNSRNAPLAGFGYGLPISRLYAKYFQGDLNLYSLSGYGTDAIIYLKALSSES 371 STAP P ++ +R APLAGFGYGLPISRLYA+YFQGDL LYS+ G GTDA+IYLKALSSES Sbjct: 319 STAPRPSLEPTRAAPLAGFGYGLPISRLYARYFQGDLKLYSMEGVGTDAVIYLKALSSES 378 Query: 372 IEKLPVFNKSAFKHYQMSSEADDWCIPSREPKNLAKEVA 410 E+LPVFNKSA++HY+ + EADDW PS EP++ +K A Sbjct: 379 FERLPVFNKSAWRHYKTTPEADDWSNPSSEPRDASKYKA 417 >4DZY-A nrPDB Length = 418 Score = 159 bits (401), Expect = 3e-39, Method: Compositional matrix adjust. Identities = 101/331 (30%), Positives = 168/331 (50%), Gaps = 33/331 (9%) Query: 53 SFAFLRQELPVRLANILKEIDILPTQLVNTSSVQLVKSWYIQSLMDLVEFHEKSPDDQKA 112 S +L+QELPVR+A+ +K LP + ++ V YI++ L +F DQ Sbjct: 90 SGRYLQQELPVRIAHRIKGFRSLPFIIGCNPTILHVHELYIRAFQKLTDF--PPIKDQAD 147 Query: 113 LSDFVDTLIKVRNRHHNVVPTMAQGIIEYKDACTVDPVTNQNLQYFLDRFYMNRISTRML 172 + + + ++ + H +VV +A+G+ E + + + ++YFLD+ +R+ RML Sbjct: 148 EAQYCQLVRQLLDDHKDVVTLLAEGLRESRKHIEDEKL----VRYFLDKTLTSRLGIRML 203 Query: 173 MNQHILIFSDSQTGNPSHIGSIDPNCDVVAVVQDAFECSRMLCDQYYLSSPELKLT-QVN 231 H+ + D P +G I +++ + +R LC+ Y ++P +++ V Sbjct: 204 ATHHLALHED----KPDFVGIICTRLSPKKIIEKWVDFARRLCEHKYGNAPRVRINGHVA 259 Query: 232 GKFPDQPIHIVYVPSHLHHMLFELFKNAMRATVEHQENQPSLTPIEVIVVLGKE-DLTIK 290 +FP ++P L ++L EL KNAMRAT+E + P P VI + + DL I+ Sbjct: 260 ARFP-------FIPMPLDYILPELLKNAMRATMESHLDTPYNVPDVVITIANNDVDLIIR 312 Query: 291 ISDRGGGVPLRIIDRLFSYTYSTAPTPVMD--------------NSRNAPLAGFGYGLPI 336 ISDRGGG+ + +DR+ Y ++TA D ++ P+ GFG+GLP Sbjct: 313 ISDRGGGIAHKDLDRVMDYHFTTAEASTQDPRISPLFGHLDMHSGGQSGPMHGFGFGLPT 372 Query: 337 SRLYAKYFQGDLNLYSLSGYGTDAIIYLKAL 367 SR YA+Y G L L SL G GTD + L+ + Sbjct: 373 SRAYAEYLGGSLQLQSLQGIGTDVYLRLRHI 403 >3SL2-A nrPDB Length = 177 Score = 43.5 bits (101), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 31/125 (24%), Positives = 57/125 (45%), Gaps = 11/125 (8%) Query: 234 FPDQPIHIVYVPSHLHHMLFELFKNAMRATVEHQENQPSLTPIEVIVVLGKEDLTIKISD 293 PD+ +++ + +L + NA++ + E S+ E +E L I + D Sbjct: 30 LPDRDLYVEIDQDKITQVLDNIISNALKYSPEGGHVTFSIDVNE-----EEELLYISVKD 84 Query: 294 RGGGVPLRIIDRLFSYTYSTAPTPVMDNSRNAPLAGFGYGLPISRLYAKYFQGDLNLYSL 353 G G+P + ++++F Y +D +R L G G GL I++ + GD+ S+ Sbjct: 85 EGIGIPKKDVEKVFDRFYR------VDKARTRKLGGTGLGLAIAKEMVQAHGGDIWADSI 138 Query: 354 SGYGT 358 G GT Sbjct: 139 EGKGT 143 >5LFK-A nrPDB Length = 298 Score = 39.3 bits (90), Expect = 0.004, Method: Compositional matrix adjust. Identities = 31/103 (30%), Positives = 45/103 (43%), Gaps = 15/103 (14%) Query: 234 FPDQPIHIVYVPSHLHHMLFELFKNAMRATVEHQENQPSLTPIEVIVVLGKEDLTIKISD 293 FP P + P+ L L + +NA+R S T IEV + K+ +TI + D Sbjct: 177 FPPGPWPLYGNPNALESALENIVRNALRY---------SHTKIEVGFAVDKDGITITVDD 227 Query: 294 RGGGVPLRIIDRLFSYTYSTAPTPVMDNSRNAPLAGFGYGLPI 336 G GV +++F Y T D +R+ G G GL I Sbjct: 228 DGPGVSPEDREQIFRPFYRT------DEARDRESGGTGLGLAI 264 >6AZR-A nrPDB Length = 259 Score = 37.7 bits (86), Expect = 0.009, Method: Compositional matrix adjust. Identities = 30/129 (23%), Positives = 59/129 (45%), Gaps = 14/129 (10%) Query: 238 PIHIVYVPSHLHHMLFELFKNAMRATVEHQENQPSLTPIEVIVVLGKED--LTIKISDRG 295 P+ P+ + +L L N ++ + +++ P V V+L ++D + I + D G Sbjct: 130 PVEAYIDPTRIRQVLLNLLNNGVKYS---KKDAPDKY---VKVILDEKDGGVLIIVEDNG 183 Query: 296 GGVPLRIIDRLFSYTYSTAPTPVMDNSRNAPLAGFGYGLPISRLYAKYFQGDLNLYSLSG 355 G+P DR+F Y +D+S + G G GL I++ + G + + S G Sbjct: 184 IGIPDHAKDRIFEQFYR------VDSSLTYEVPGTGLGLAITKEIVELHGGRIWVESEVG 237 Query: 356 YGTDAIIYL 364 G+ +++ Sbjct: 238 KGSRFFVWI 246 >4I5S-A nrPDB Length = 450 Score = 37.7 bits (86), Expect = 0.010, Method: Compositional matrix adjust. Identities = 30/139 (21%), Positives = 60/139 (43%), Gaps = 13/139 (9%) Query: 226 KLTQVNGKFPDQPIHIVYVPSHLHHMLFELFKNAMRATVEHQENQPSLTPIEVIVVLGKE 285 K+ ++ +PD+ + I + ++ + NA++ + P + + + Sbjct: 306 KVYEIIRDYPDKSVWIEIDTDKMTQVIDNILNNAIKYS-------PDGGKVTITMQTTDT 358 Query: 286 DLTIKISDRGGGVPLRIIDRLFSYTYSTAPTPVMDNSRNAPLAGFGYGLPISRLYAKYFQ 345 L + ISD+G G+P + + +F Y +D +R+ G G GL I++ K + Sbjct: 359 QLILSISDQGLGIPKKDLPLIFDRFYR------VDKARSRAQGGTGLGLAIAKEIVKQHK 412 Query: 346 GDLNLYSLSGYGTDAIIYL 364 G + S G G+ I L Sbjct: 413 GFIWANSEEGEGSTFTIVL 431 >5CPH-A nrPDB Length = 212 Score = 35.0 bits (79), Expect = 0.063, Method: Compositional matrix adjust. Identities = 18/59 (30%), Positives = 36/59 (61%), Gaps = 8/59 (13%) Query: 248 LHHMLFELFKNAMRATVEHQENQPSLTPIEVIVVLGKEDLTIKISDRGGGVPLRIIDRL 306 LHH+++E+ N++ + NQ IEV++ ++D IK++D G G+P+ I +++ Sbjct: 45 LHHLVWEIVDNSIDEALAGYANQ-----IEVVI---EKDNWIKVTDNGRGIPVDIQEKM 95 >4GCZ-A nrPDB Length = 385 Score = 34.7 bits (78), Expect = 0.069, Method: Compositional matrix adjust. Identities = 24/92 (26%), Positives = 39/92 (42%), Gaps = 16/92 (17%) Query: 247 HLHHMLFELFKNAMRATVEHQENQPSLTPIEVIVVLGKEDLTIKISDRGGGVPLRIIDRL 306 + +L LF+NA+ A + Q + +T + + +++SD G G +I L Sbjct: 268 QIQQVLVNLFRNALEAMAQSQRRELVVTNTPA----ADDMIEVEVSDTGSGFQDDVIPNL 323 Query: 307 FSYTYSTAPTPVMDNSRNAPLAGFGYGLPISR 338 F ++T T G G GL ISR Sbjct: 324 FQTFFTTKDT------------GMGVGLSISR 343 >4URM-A nrPDB Length = 231 Score = 34.7 bits (78), Expect = 0.071, Method: Compositional matrix adjust. Identities = 18/59 (30%), Positives = 36/59 (61%), Gaps = 8/59 (13%) Query: 248 LHHMLFELFKNAMRATVEHQENQPSLTPIEVIVVLGKEDLTIKISDRGGGVPLRIIDRL 306 LHH+++E+ N++ + NQ IEV++ ++D IK++D G G+P+ I +++ Sbjct: 44 LHHLVWEIVDNSIDEALAGYANQ-----IEVVI---EKDNWIKVTDNGRGIPVDIQEKM 94 >1PVG-A nrPDB Length = 418 Score = 31.2 bits (69), Expect = 0.84, Method: Compositional matrix adjust. Identities = 23/110 (20%), Positives = 52/110 (47%), Gaps = 15/110 (13%) Query: 252 LFELFKNAMRATVEHQENQPSLTPIEVIVVLGKEDLTIKISDRGGGVPLRIIDR------ 305 LF++F + +++ PS+ I+V + E+ TI++ + G G+P+ I ++ Sbjct: 65 LFKIFDEILVNAADNKVRDPSMKRIDVNI--HAEEHTIEVKNDGKGIPIEIHNKENIYIP 122 Query: 306 --LFSYTYSTAPTPVMDNSRNAPLAGFGYGLPISRLYAKYF---QGDLNL 350 +F + +++ D+ + GYG + +++ F DLN+ Sbjct: 123 EMIFGHLLTSSNYD--DDEKKVTGGRNGYGAKLCNIFSTEFILETADLNV 170 >2DGN-A nrPDB Length = 457 Score = 30.0 bits (66), Expect = 1.8, Method: Compositional matrix adjust. Identities = 20/63 (31%), Positives = 34/63 (53%), Gaps = 5/63 (7%) Query: 70 KEID--ILPTQLVNTSSVQLVKSWYIQSLMDLVEFHEKSPDDQKALSDFVDTLIKVRNRH 127 KE D +LP+ ++NT +V + + + L L F E +++K L D+ LI + +R Sbjct: 78 KEYDFHLLPSGIINTKAVSFIGNGVVIHLPGL--FEEAEKNEKKGLKDWEKRLI-ISDRA 134 Query: 128 HNV 130 H V Sbjct: 135 HLV 137 >4PL9-A nrPDB Length = 183 Score = 30.0 bits (66), Expect = 1.9, Method: Compositional matrix adjust. Identities = 34/153 (22%), Positives = 59/153 (38%), Gaps = 31/153 (20%) Query: 235 PDQPIHIVYVPSHLHHMLFELFKNAMRATVEHQENQPSLTPIEVIVVLGKED-------- 286 PD P +V L ++ + NA++ + + I V ++ K D Sbjct: 41 PDLPEFVVGDEKRLMQIILNIVGNAVKFSKQGS--------ISVTALVTKSDTRAADFFV 92 Query: 287 --------LTIKISDRGGGVPLRIIDRLFSYTYSTAPTPVMDNSRNAPLAGFGYGLPISR 338 L +K+ D G G+ + I ++F+ T + G G GL IS+ Sbjct: 93 VPTGSHFYLRVKVKDSGAGINPQDIPKIFTKFAQTQSLATRSS------GGSGLGLAISK 146 Query: 339 LYAKYFQGDLNLYSLS-GYGTDAIIYLKALSSE 370 + +G++ + S G G AI +K SE Sbjct: 147 RFVNLMEGNIWIESDGLGKGCTAIFDVKLGISE 179 >1SQG-A nrPDB Length = 429 Score = 30.0 bits (66), Expect = 2.1, Method: Compositional matrix adjust. Identities = 19/64 (29%), Positives = 29/64 (45%), Gaps = 1/64 (1%) Query: 174 NQHILIFSDSQTGNPSHIGSIDPNCDVVAVVQDAFECSRMLCDQYYLSSPELKLTQVNGK 233 +HIL + G +HI + P VVAV D SR+ D + + Q +G+ Sbjct: 247 GEHILDLCAAPGGKTTHILEVAPEAQVVAVDIDEQRLSRVY-DNLKRLGMKATVKQGDGR 305 Query: 234 FPDQ 237 +P Q Sbjct: 306 YPSQ 309 >4PU9-A nrPDB Length = 398 Score = 28.9 bits (63), Expect = 4.3, Method: Compositional matrix adjust. Identities = 19/56 (33%), Positives = 29/56 (51%), Gaps = 10/56 (17%) Query: 248 LHHMLFELFKNAM-RATVEHQENQPSLTPIEVIVVLGKEDLTIKISDRGGGVPLRI 302 LHHM+FE+ NA+ A H + E+IV + D ++ + D G G+P I Sbjct: 42 LHHMVFEVVDNAIDEALAGHCK--------EIIVTI-HADNSVSVQDDGRGIPTGI 88 >4ZI9-A nrPDB Length = 318 Score = 28.9 bits (63), Expect = 4.4, Method: Compositional matrix adjust. Identities = 19/67 (28%), Positives = 34/67 (50%), Gaps = 8/67 (11%) Query: 176 HILIFSDSQTGNPSHIGSIDPNCDVVAVVQDAFECSRMLCDQYYLSSPE-----LKLTQV 230 H L+ + S G+P H G++ + VV V + ++ +Y++S PE +L +V Sbjct: 181 HYLVLTASDGGSPIHSGTLQIHVQVVDVNDNPPAFTKA---EYHVSVPENVPLGTRLLKV 237 Query: 231 NGKFPDQ 237 N PD+ Sbjct: 238 NATDPDE 244 >4XEM-A nrPDB Length = 475 Score = 28.9 bits (63), Expect = 4.4, Method: Compositional matrix adjust. Identities = 10/16 (62%), Positives = 12/16 (75%) Query: 332 YGLPISRLYAKYFQGD 347 +G+PI RLY YF GD Sbjct: 146 FGIPIERLYVTYFGGD 161 >5SZL-A nrPDB Length = 427 Score = 28.5 bits (62), Expect = 4.9, Method: Compositional matrix adjust. Identities = 19/67 (28%), Positives = 34/67 (50%), Gaps = 8/67 (11%) Query: 176 HILIFSDSQTGNPSHIGSIDPNCDVVAVVQDAFECSRMLCDQYYLSSPE-----LKLTQV 230 H L+ + S G+P H G++ + VV V + ++ +Y++S PE +L +V Sbjct: 180 HYLVLTASDGGSPIHSGTLQIHVQVVDVNDNPPAFTKA---EYHVSVPENVPLGTRLLKV 236 Query: 231 NGKFPDQ 237 N PD+ Sbjct: 237 NATDPDE 243 >5MMP-A nrPDB Length = 234 Score = 28.5 bits (62), Expect = 5.5, Method: Compositional matrix adjust. Identities = 19/56 (33%), Positives = 29/56 (51%), Gaps = 10/56 (17%) Query: 248 LHHMLFELFKNAM-RATVEHQENQPSLTPIEVIVVLGKEDLTIKISDRGGGVPLRI 302 LHHM+FE+ NA+ A H + E+IV + D ++ + D G G+P I Sbjct: 50 LHHMVFEVVDNAIDEALAGHCK--------EIIVTI-HADNSVSVQDDGRGIPTGI 96 >3EJX-A nrPDB Length = 317 Score = 28.5 bits (62), Expect = 6.3, Method: Compositional matrix adjust. Identities = 13/36 (36%), Positives = 20/36 (55%) Query: 265 EHQENQPSLTPIEVIVVLGKEDLTIKISDRGGGVPL 300 EH E P+ T E + VL + L +++ +RG G L Sbjct: 217 EHHEMFPARTNTEFVEVLSRSHLKMRVWERGAGATL 252 >3VNK-A nrPDB Length = 293 Score = 27.7 bits (60), Expect = 9.5, Method: Compositional matrix adjust. Identities = 16/49 (32%), Positives = 26/49 (53%), Gaps = 5/49 (10%) Query: 117 VDTLIKVRNRHHNVVPTMAQGIIEYKDACTVDPVTNQNLQYFLDRFYMN 165 VD ++V NR N + AQ +++ V V + N++ LD F+MN Sbjct: 145 VDFCLEVLNRFENYLINTAQEGVDF-----VKQVDHNNVKVMLDTFHMN 188 >5IDJ-A nrPDB Length = 242 Score = 27.7 bits (60), Expect = 9.6, Method: Compositional matrix adjust. Identities = 16/59 (27%), Positives = 28/59 (47%), Gaps = 12/59 (20%) Query: 289 IKISDRGGGVPLRIIDRLFSYTYSTAPTPVMDNSRNAPLAGFGYGLPISRLYAKYFQGD 347 I++SD G G+P ++ ++F ++T P G G GL ++ +Y Q D Sbjct: 172 IEVSDDGPGIPPDVMGKIFDPFFTTKPV------------GEGTGLGLATVYGIVKQSD 218 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 2E0A-A nrPDB 682 0.0 3CRK-A nrPDB 659 0.0 2Q8F-A nrPDB 654 0.0 1Y8N-A nrPDB 644 0.0 4DZY-A nrPDB 404 e-113 3SL2-A nrPDB 151 5e-37 Sequences not found previously or not previously below threshold: 4I5S-A nrPDB 100 2e-21 4U7O-A nrPDB 99 3e-21 6AZR-A nrPDB 74 1e-13 5LFK-A nrPDB 59 3e-09 4PL9-A nrPDB 58 6e-09 4GCZ-A nrPDB 55 6e-08 3D36-A nrPDB 50 2e-06 4Q20-A nrPDB 50 2e-06 6BLK-C nrPDB 49 5e-06 1R62-A nrPDB 47 1e-05 6DK7-A nrPDB 46 3e-05 1ID0-A nrPDB 43 3e-04 1YSR-A nrPDB 40 0.001 3CGZ-A nrPDB 38 0.007 1MX0-A nrPDB 38 0.009 2ZBK-B nrPDB 38 0.010 5IDM-A nrPDB 37 0.013 5IDJ-A nrPDB 37 0.013 3JZ3-A nrPDB 37 0.019 4JPB-A nrPDB 35 0.050 1I5D-A nrPDB 35 0.063 4XIV-A nrPDB 35 0.071 3JA6-C nrPDB 34 0.11 4KP4-A nrPDB 33 0.21 4CTI-A nrPDB 33 0.21 1BXD-A nrPDB 33 0.21 5CPH-A nrPDB 33 0.22 4URM-A nrPDB 33 0.22 5MMP-A nrPDB 32 0.42 4PU9-A nrPDB 32 0.42 4XEM-A nrPDB 31 1.2 1XRE-A nrPDB 30 1.5 4OKD-A nrPDB 29 3.2 4RLP-A nrPDB 29 3.4 4L42-A nrPDB 29 3.4 1TID-A nrPDB 29 3.4 1OR4-A nrPDB 29 4.6 5GUP-v nrPDB 29 4.8 2VCE-A nrPDB 29 5.3 2OTN-A nrPDB 29 6.0 4HZ5-A nrPDB 29 6.2 5SZL-A nrPDB 28 6.4 4ZI9-A nrPDB 28 6.4 4YRY-B nrPDB 28 7.3 4YIR-X nrPDB 28 8.3 >2E0A-A nrPDB Length = 394 Score = 682 bits (1761), Expect = 0.0, Method: Composition-based stats. Identities = 393/394 (99%), Positives = 393/394 (99%) Query: 18 GLVPREVEHFSRYSPSPLSMKQLLDFGSENACERTSFAFLRQELPVRLANILKEIDILPT 77 G VPREVEHFSRYSPSPLSMKQLLDFGSENACERTSFAFLRQELPVRLANILKEIDILPT Sbjct: 1 GPVPREVEHFSRYSPSPLSMKQLLDFGSENACERTSFAFLRQELPVRLANILKEIDILPT 60 Query: 78 QLVNTSSVQLVKSWYIQSLMDLVEFHEKSPDDQKALSDFVDTLIKVRNRHHNVVPTMAQG 137 QLVNTSSVQLVKSWYIQSLMDLVEFHEKSPDDQKALSDFVDTLIKVRNRHHNVVPTMAQG Sbjct: 61 QLVNTSSVQLVKSWYIQSLMDLVEFHEKSPDDQKALSDFVDTLIKVRNRHHNVVPTMAQG 120 Query: 138 IIEYKDACTVDPVTNQNLQYFLDRFYMNRISTRMLMNQHILIFSDSQTGNPSHIGSIDPN 197 IIEYKDACTVDPVTNQNLQYFLDRFYMNRISTRMLMNQHILIFSDSQTGNPSHIGSIDPN Sbjct: 121 IIEYKDACTVDPVTNQNLQYFLDRFYMNRISTRMLMNQHILIFSDSQTGNPSHIGSIDPN 180 Query: 198 CDVVAVVQDAFECSRMLCDQYYLSSPELKLTQVNGKFPDQPIHIVYVPSHLHHMLFELFK 257 CDVVAVVQDAFECSRMLCDQYYLSSPELKLTQVNGKFPDQPIHIVYVPSHLHHMLFELFK Sbjct: 181 CDVVAVVQDAFECSRMLCDQYYLSSPELKLTQVNGKFPDQPIHIVYVPSHLHHMLFELFK 240 Query: 258 NAMRATVEHQENQPSLTPIEVIVVLGKEDLTIKISDRGGGVPLRIIDRLFSYTYSTAPTP 317 NAMRATVEHQENQPSLTPIEVIVVLGKEDLTIKISDRGGGVPLRIIDRLFSYTYSTAPTP Sbjct: 241 NAMRATVEHQENQPSLTPIEVIVVLGKEDLTIKISDRGGGVPLRIIDRLFSYTYSTAPTP 300 Query: 318 VMDNSRNAPLAGFGYGLPISRLYAKYFQGDLNLYSLSGYGTDAIIYLKALSSESIEKLPV 377 VMDNSRNAPLAGFGYGLPISRLYAKYFQGDLNLYSLSGYGTDAIIYLKALSSESIEKLPV Sbjct: 301 VMDNSRNAPLAGFGYGLPISRLYAKYFQGDLNLYSLSGYGTDAIIYLKALSSESIEKLPV 360 Query: 378 FNKSAFKHYQMSSEADDWCIPSREPKNLAKEVAM 411 FNKSAFKHYQMSSEADDWCIPSREPKNLAKEVAM Sbjct: 361 FNKSAFKHYQMSSEADDWCIPSREPKNLAKEVAM 394 >3CRK-A nrPDB Length = 407 Score = 659 bits (1701), Expect = 0.0, Method: Composition-based stats. Identities = 265/410 (64%), Positives = 339/410 (82%), Gaps = 6/410 (1%) Query: 1 MKAARFVLRSAGSLNGAGLVPREVEHFSRYSPSPLSMKQLLDFGSENACERTSFAFLRQE 60 M+ R +L++A SL GA P+ +EHFS++SPSPLSMKQ LDFGS NACE+TSF FLRQE Sbjct: 1 MRWFRALLKNA-SLAGA---PKYIEHFSKFSPSPLSMKQFLDFGSSNACEKTSFTFLRQE 56 Query: 61 LPVRLANILKEIDILPTQLVNTSSVQLVKSWYIQSLMDLVEFHEKSPDDQKALSDFVDTL 120 LPVRLANI+KEI++LP ++++T SVQLV+SWY+QSL+D++EF +K P+D + LS F D L Sbjct: 57 LPVRLANIMKEINLLPDRVLSTPSVQLVQSWYVQSLLDIMEFLDKDPEDHRTLSQFTDAL 116 Query: 121 IKVRNRHHNVVPTMAQGIIEYKDACTVDPVTNQNLQYFLDRFYMNRISTRMLMNQHILIF 180 + +RNRH++VVPTMAQG++EYKD DPV+NQN+QYFLDRFY++RIS RML+NQH LIF Sbjct: 117 VTIRNRHNDVVPTMAQGVLEYKDTYGDDPVSNQNIQYFLDRFYLSRISIRMLINQHTLIF 176 Query: 181 SDS-QTGNPSHIGSIDPNCDVVAVVQDAFECSRMLCDQYYLSSPELKLTQVNGKFPDQPI 239 S +P HIGSIDPNC V VV+DA++ +++LCD+YY++SP+L++ +VN QPI Sbjct: 177 DGSTNPAHPKHIGSIDPNCSVSDVVKDAYDMAKLLCDKYYMASPDLEIQEVNATNATQPI 236 Query: 240 HIVYVPSHLHHMLFELFKNAMRATVEHQENQPSLTPIEVIVVLGKEDLTIKISDRGGGVP 299 H+VYVPSHL+HMLFELFKNAMRATVE E+ +L PI+++V LG+EDL+IK+SDRGGGVP Sbjct: 237 HMVYVPSHLYHMLFELFKNAMRATVESHESSLTLPPIKIMVALGEEDLSIKMSDRGGGVP 296 Query: 300 LRIIDRLFSYTYSTAPTPVMDNSRNAPLAGFGYGLPISRLYAKYFQGDLNLYSLSGYGTD 359 LR I+RLFSY YSTAPTP + PLAGFGYGLPISRLYAKYFQGDL L+S+ G+GTD Sbjct: 297 LRKIERLFSYMYSTAPTP-QPGTGGTPLAGFGYGLPISRLYAKYFQGDLQLFSMEGFGTD 355 Query: 360 AIIYLKALSSESIEKLPVFNKSAFKHYQMSSEADDWCIPSREPKNLAKEV 409 A+IYLKALS++S+E+LPV+NKSA++HYQ EA DWC+PS EPKN + Sbjct: 356 AVIYLKALSTDSVERLPVYNKSAWRHYQTIQEAGDWCVPSTEPKNTSTYR 405 >2Q8F-A nrPDB Length = 407 Score = 654 bits (1688), Expect = 0.0, Method: Composition-based stats. Identities = 265/404 (65%), Positives = 333/404 (82%), Gaps = 3/404 (0%) Query: 10 SAGSLNGAGLVPREVEHFSRYSPSPLSMKQLLDFGSENACERTSFAFLRQELPVRLANIL 69 S S VP +V+ ++R+SPSPLSMKQ LDFGS NACE+TSF FLRQELPVRLANI+ Sbjct: 3 SGSSPASERGVPGQVDFYARFSPSPLSMKQFLDFGSVNACEKTSFMFLRQELPVRLANIM 62 Query: 70 KEIDILPTQLVNTSSVQLVKSWYIQSLMDLVEFHEKSPDDQKALSDFVDTLIKVRNRHHN 129 KEI +LP L+ T SVQLV+SWYIQSL +L++F +KS +D KA+ DF DT+I++RNRH++ Sbjct: 63 KEISLLPDNLLRTPSVQLVQSWYIQSLQELLDFKDKSAEDAKAIYDFTDTVIRIRNRHND 122 Query: 130 VVPTMAQGIIEYKDACTVDPVTNQNLQYFLDRFYMNRISTRMLMNQHILIFSDSQTGNPS 189 V+PTMAQG+IEYK++ VDPVT+QN+QYFLDRFYM+RIS RML+NQH L+F G+PS Sbjct: 123 VIPTMAQGVIEYKESFGVDPVTSQNVQYFLDRFYMSRISIRMLLNQHSLLFGGKGKGSPS 182 Query: 190 H---IGSIDPNCDVVAVVQDAFECSRMLCDQYYLSSPELKLTQVNGKFPDQPIHIVYVPS 246 H IGSI+PNC+V+ V++D +E +R LCD YY++SPEL+L ++N K P QPI +VYVPS Sbjct: 183 HRKHIGSINPNCNVLEVIKDGYENARRLCDLYYINSPELELEELNAKSPGQPIQVVYVPS 242 Query: 247 HLHHMLFELFKNAMRATVEHQENQPSLTPIEVIVVLGKEDLTIKISDRGGGVPLRIIDRL 306 HL+HM+FELFKNAMRAT+EH N+ PI+V V LG EDLT+K+SDRGGGVPLR IDRL Sbjct: 243 HLYHMVFELFKNAMRATMEHHANRGVYPPIQVHVTLGNEDLTVKMSDRGGGVPLRKIDRL 302 Query: 307 FSYTYSTAPTPVMDNSRNAPLAGFGYGLPISRLYAKYFQGDLNLYSLSGYGTDAIIYLKA 366 F+Y YSTAP P ++ SR PLAGFGYGLPISRLYA+YFQGDL LYSL GYGTDA+IY+KA Sbjct: 303 FNYMYSTAPRPRVETSRAVPLAGFGYGLPISRLYAQYFQGDLKLYSLEGYGTDAVIYIKA 362 Query: 367 LSSESIEKLPVFNKSAFKHYQMSSEADDWCIPSREPKNLAKEVA 410 LS++SIE+LPV+NK+A+KHY + EADDWC+PSREPK++ + Sbjct: 363 LSTDSIERLPVYNKAAWKHYNTNHEADDWCVPSREPKDMTTFRS 406 >1Y8N-A nrPDB Length = 419 Score = 644 bits (1661), Expect = 0.0, Method: Composition-based stats. Identities = 251/399 (62%), Positives = 321/399 (80%), Gaps = 2/399 (0%) Query: 14 LNGAGLVPREVEHFSRYSPSPLSMKQLLDFGSENACERTSFAFLRQELPVRLANILKEID 73 G VP+++E +SR+SPSPLS+KQ LDFG +NACE+TS+ FLR+ELPVRLAN ++E++ Sbjct: 19 FQGKQPVPKQIERYSRFSPSPLSIKQFLDFGRDNACEKTSYMFLRKELPVRLANTMREVN 78 Query: 74 ILPTQLVNTSSVQLVKSWYIQSLMDLVEFHEKSPDDQKALSDFVDTLIKVRNRHHNVVPT 133 +LP L+N SV LV+SWY+QS ++L+E+ KSP+D + L +F+ LIKVRNRH++VVPT Sbjct: 79 LLPDNLLNRPSVGLVQSWYMQSFLELLEYENKSPEDPQVLDNFLQVLIKVRNRHNDVVPT 138 Query: 134 MAQGIIEYKDACTVDPVTNQNLQYFLDRFYMNRISTRMLMNQHILIF-SDSQTGNPSHIG 192 MAQG+IEYK+ DP + N+QYFLDRFY NRIS RML+NQH L+F D+ +P HIG Sbjct: 139 MAQGVIEYKEKFGFDPFISTNIQYFLDRFYTNRISFRMLINQHTLLFGGDTNPVHPKHIG 198 Query: 193 SIDPNCDVVAVVQDAFECSRMLCDQYYLSSPELKLTQVNGKFPDQPIHIVYVPSHLHHML 252 SIDP C+V VV+DA+E ++MLC+QYYL +PEL++ + N K PD+PI +VYVPSHL HML Sbjct: 199 SIDPTCNVADVVKDAYETAKMLCEQYYLVAPELEVEEFNAKAPDKPIQVVYVPSHLFHML 258 Query: 253 FELFKNAMRATVEHQENQPSLTP-IEVIVVLGKEDLTIKISDRGGGVPLRIIDRLFSYTY 311 FELFKN+MRATVE E++ P ++ +V LGKEDL+IKISD GGGVPLR IDRLF+Y Y Sbjct: 259 FELFKNSMRATVELYEDRKEGYPAVKTLVTLGKEDLSIKISDLGGGVPLRKIDRLFNYMY 318 Query: 312 STAPTPVMDNSRNAPLAGFGYGLPISRLYAKYFQGDLNLYSLSGYGTDAIIYLKALSSES 371 STAP P ++ +R APLAGFGYGLPISRLYA+YFQGDL LYS+ G GTDA+IYLKALSSES Sbjct: 319 STAPRPSLEPTRAAPLAGFGYGLPISRLYARYFQGDLKLYSMEGVGTDAVIYLKALSSES 378 Query: 372 IEKLPVFNKSAFKHYQMSSEADDWCIPSREPKNLAKEVA 410 E+LPVFNKSA++HY+ + EADDW PS EP++ +K A Sbjct: 379 FERLPVFNKSAWRHYKTTPEADDWSNPSSEPRDASKYKA 417 >4DZY-A nrPDB Length = 418 Score = 404 bits (1037), Expect = e-113, Method: Composition-based stats. Identities = 101/331 (30%), Positives = 168/331 (50%), Gaps = 33/331 (9%) Query: 53 SFAFLRQELPVRLANILKEIDILPTQLVNTSSVQLVKSWYIQSLMDLVEFHEKSPDDQKA 112 S +L+QELPVR+A+ +K LP + ++ V YI++ L +F DQ Sbjct: 90 SGRYLQQELPVRIAHRIKGFRSLPFIIGCNPTILHVHELYIRAFQKLTDF--PPIKDQAD 147 Query: 113 LSDFVDTLIKVRNRHHNVVPTMAQGIIEYKDACTVDPVTNQNLQYFLDRFYMNRISTRML 172 + + + ++ + H +VV +A+G+ E + + + ++YFLD+ +R+ RML Sbjct: 148 EAQYCQLVRQLLDDHKDVVTLLAEGLRESRKHIEDEKL----VRYFLDKTLTSRLGIRML 203 Query: 173 MNQHILIFSDSQTGNPSHIGSIDPNCDVVAVVQDAFECSRMLCDQYYLSSPELKLT-QVN 231 H+ + D P +G I +++ + +R LC+ Y ++P +++ V Sbjct: 204 ATHHLALHED----KPDFVGIICTRLSPKKIIEKWVDFARRLCEHKYGNAPRVRINGHVA 259 Query: 232 GKFPDQPIHIVYVPSHLHHMLFELFKNAMRATVEHQENQPSLTPIEVIVVLGKE-DLTIK 290 +FP ++P L ++L EL KNAMRAT+E + P P VI + + DL I+ Sbjct: 260 ARFP-------FIPMPLDYILPELLKNAMRATMESHLDTPYNVPDVVITIANNDVDLIIR 312 Query: 291 ISDRGGGVPLRIIDRLFSYTYSTAPTPVMD--------------NSRNAPLAGFGYGLPI 336 ISDRGGG+ + +DR+ Y ++TA D ++ P+ GFG+GLP Sbjct: 313 ISDRGGGIAHKDLDRVMDYHFTTAEASTQDPRISPLFGHLDMHSGGQSGPMHGFGFGLPT 372 Query: 337 SRLYAKYFQGDLNLYSLSGYGTDAIIYLKAL 367 SR YA+Y G L L SL G GTD + L+ + Sbjct: 373 SRAYAEYLGGSLQLQSLQGIGTDVYLRLRHI 403 >3SL2-A nrPDB Length = 177 Score = 151 bits (382), Expect = 5e-37, Method: Composition-based stats. Identities = 32/136 (23%), Positives = 59/136 (43%), Gaps = 11/136 (8%) Query: 229 QVNGKFPDQPIHIVYVPSHLHHMLFELFKNAMRATVEHQENQPSLTPIEVIVVLGKEDLT 288 + PD+ +++ + +L + NA++ + E S+ E +E L Sbjct: 25 EFIRNLPDRDLYVEIDQDKITQVLDNIISNALKYSPEGGHVTFSIDVNE-----EEELLY 79 Query: 289 IKISDRGGGVPLRIIDRLFSYTYSTAPTPVMDNSRNAPLAGFGYGLPISRLYAKYFQGDL 348 I + D G G+P + ++++F Y +D +R L G G GL I++ + GD+ Sbjct: 80 ISVKDEGIGIPKKDVEKVFDRFYR------VDKARTRKLGGTGLGLAIAKEMVQAHGGDI 133 Query: 349 NLYSLSGYGTDAIIYL 364 S+ G GT L Sbjct: 134 WADSIEGKGTTITFTL 149 >4I5S-A nrPDB Length = 450 Score = 99.8 bits (247), Expect = 2e-21, Method: Composition-based stats. Identities = 29/139 (20%), Positives = 61/139 (43%), Gaps = 13/139 (9%) Query: 226 KLTQVNGKFPDQPIHIVYVPSHLHHMLFELFKNAMRATVEHQENQPSLTPIEVIVVLGKE 285 K+ ++ +PD+ + I + ++ + NA++ + + + ++ + Sbjct: 306 KVYEIIRDYPDKSVWIEIDTDKMTQVIDNILNNAIKYSPDGGKVTITMQTTDT------- 358 Query: 286 DLTIKISDRGGGVPLRIIDRLFSYTYSTAPTPVMDNSRNAPLAGFGYGLPISRLYAKYFQ 345 L + ISD+G G+P + + +F Y +D +R+ G G GL I++ K + Sbjct: 359 QLILSISDQGLGIPKKDLPLIFDRFYR------VDKARSRAQGGTGLGLAIAKEIVKQHK 412 Query: 346 GDLNLYSLSGYGTDAIIYL 364 G + S G G+ I L Sbjct: 413 GFIWANSEEGEGSTFTIVL 431 >4U7O-A nrPDB Length = 277 Score = 99.4 bits (246), Expect = 3e-21, Method: Composition-based stats. Identities = 26/132 (19%), Positives = 53/132 (40%), Gaps = 13/132 (9%) Query: 233 KFPDQPIHIVYVPSHLHHMLFELFKNAMRATVEHQENQPSLTPIEVIVVLGKEDLTIKIS 292 +F + + + +L + NA++ + + ++ + I IS Sbjct: 142 EFTKRDLWVEIDTDKFTQVLDNIMNNAIKYSPDGGVVT-------CRLLETHNQVIISIS 194 Query: 293 DRGGGVPLRIIDRLFSYTYSTAPTPVMDNSRNAPLAGFGYGLPISRLYAKYFQGDLNLYS 352 D+G G+P + +F + +D +R+ G G GL IS+ + G + + S Sbjct: 195 DQGLGIPRADLGHVFDRFFR------VDKARSRAQGGTGLGLAISKEVVQMLGGRIWVDS 248 Query: 353 LSGYGTDAIIYL 364 + G G+ I L Sbjct: 249 VEGKGSTFYISL 260 >6AZR-A nrPDB Length = 259 Score = 74.0 bits (180), Expect = 1e-13, Method: Composition-based stats. Identities = 29/129 (22%), Positives = 58/129 (44%), Gaps = 14/129 (10%) Query: 238 PIHIVYVPSHLHHMLFELFKNAMRATVEHQENQPSLTPIEVIVVLGKED--LTIKISDRG 295 P+ P+ + +L L N ++ + + ++ V V+L ++D + I + D G Sbjct: 130 PVEAYIDPTRIRQVLLNLLNNGVKYSKKDAPDKY------VKVILDEKDGGVLIIVEDNG 183 Query: 296 GGVPLRIIDRLFSYTYSTAPTPVMDNSRNAPLAGFGYGLPISRLYAKYFQGDLNLYSLSG 355 G+P DR+F Y +D+S + G G GL I++ + G + + S G Sbjct: 184 IGIPDHAKDRIFEQFYR------VDSSLTYEVPGTGLGLAITKEIVELHGGRIWVESEVG 237 Query: 356 YGTDAIIYL 364 G+ +++ Sbjct: 238 KGSRFFVWI 246 >5LFK-A nrPDB Length = 298 Score = 59.3 bits (142), Expect = 3e-09, Method: Composition-based stats. Identities = 35/135 (25%), Positives = 55/135 (40%), Gaps = 15/135 (11%) Query: 230 VNGKFPDQPIHIVYVPSHLHHMLFELFKNAMRATVEHQENQPSLTPIEVIVVLGKEDLTI 289 + FP P + P+ L L + +NA+R S T IEV + K+ +TI Sbjct: 173 LTVNFPPGPWPLYGNPNALESALENIVRNALRY---------SHTKIEVGFAVDKDGITI 223 Query: 290 KISDRGGGVPLRIIDRLFSYTYSTAPTPVMDNSRNAPLAGFGYGLPISRLYAKYFQGDLN 349 + D G GV +++F Y T D +R+ G G GL I + +G + Sbjct: 224 TVDDDGPGVSPEDREQIFRPFYRT------DEARDRESGGTGLGLAIVETAIQQHRGWVK 277 Query: 350 LYSLSGYGTDAIIYL 364 G +I+L Sbjct: 278 AEDSPLGGLRLVIWL 292 >4PL9-A nrPDB Length = 183 Score = 58.2 bits (139), Expect = 6e-09, Method: Composition-based stats. Identities = 33/150 (22%), Positives = 59/150 (39%), Gaps = 16/150 (10%) Query: 234 FPDQPIHIVYVPSHLHHMLFELFKNAMRATVEHQENQPSLTPIE--------VIVVLGKE 285 PD P +V L ++ + NA++ + + + +L V+ Sbjct: 40 APDLPEFVVGDEKRLMQIILNIVGNAVKFSKQGSISVTALVTKSDTRAADFFVVPTGSHF 99 Query: 286 DLTIKISDRGGGVPLRIIDRLFSYTYSTAPTPVMDNSRNAPLAGFGYGLPISRLYAKYFQ 345 L +K+ D G G+ + I ++F+ T G G GL IS+ + + Sbjct: 100 YLRVKVKDSGAGINPQDIPKIFTKFAQTQSLA------TRSSGGSGLGLAISKRFVNLME 153 Query: 346 GDLNLYSLS-GYGTDAIIYLK-ALSSESIE 373 G++ + S G G AI +K +S S E Sbjct: 154 GNIWIESDGLGKGCTAIFDVKLGISERSNE 183 >4GCZ-A nrPDB Length = 385 Score = 55.1 bits (131), Expect = 6e-08, Method: Composition-based stats. Identities = 26/118 (22%), Positives = 46/118 (38%), Gaps = 17/118 (14%) Query: 235 PDQPIHIVYVPSHLHHMLFELFKNAMRATVEHQENQPSLTPIEVIVVLGKEDLTIKISDR 294 P + ++ + +L LF+NA+ A + Q + + + + +++SD Sbjct: 257 PGADL-VLADRVQIQQVLVNLFRNALEAMAQSQRREL----VVTNTPAADDMIEVEVSDT 311 Query: 295 GGGVPLRIIDRLFSYTYSTAPTPVMDNSRNAPLAGFGYGLPISRLYAKYFQGDLNLYS 352 G G +I LF ++T T G G GL ISR + G + S Sbjct: 312 GSGFQDDVIPNLFQTFFTTKDT------------GMGVGLSISRSIIEAHGGRMWAES 357 >3D36-A nrPDB Length = 244 Score = 49.7 bits (117), Expect = 2e-06, Method: Composition-based stats. Identities = 40/232 (17%), Positives = 77/232 (33%), Gaps = 39/232 (16%) Query: 133 TMAQGIIEYKDACTVDPVTNQNLQYFLDRFYMNRISTRMLMNQHILIFSDSQTGNPSHIG 192 T A+G I+ P+ + + RI+ L +I P+ Sbjct: 30 TAARGFIQL---IEEQPLAADKRRQY------ARIAIEELDRAEAIITDYLTFAKPA--P 78 Query: 193 SIDPNCDVVAVVQDAFECSRMLCDQYYLSSPELKLTQVNGKFPDQPIHIVYVPSHLHHML 252 +V ++ + R P ++ V+ + P ++ L Sbjct: 79 ETPEKLNVKLEIERVIDILR----------PLANMSCVDIQATLAPFSVIGEREKFRQCL 128 Query: 253 FELFKNAMRATVEHQENQPSLTPIEVIVVLGKEDLTIKISDRGGGVPLRIIDRLFSYTYS 312 + KNA+ A ++V V + + I+I+D G G+ ++RL ++ Sbjct: 129 LNVMKNAIEAMPNGG-------TLQVYVSIDNGRVLIRIADTGVGMTKEQLERLGEPYFT 181 Query: 313 TAPTPVMDNSRNAPLAGFGYGLPISRLYAKYFQGDLNLYSLSGYGTDAIIYL 364 T + G G G+ + + G + + S GT IYL Sbjct: 182 TKG-----------VKGTGLGMMVVYRIIESMNGTIRIESEIHKGTTVSIYL 222 >4Q20-A nrPDB Length = 268 Score = 49.7 bits (117), Expect = 2e-06, Method: Composition-based stats. Identities = 26/112 (23%), Positives = 39/112 (34%), Gaps = 19/112 (16%) Query: 247 HLHHMLFELFKNAMRATVEHQENQPSLTPIEVIVVLGKEDLTIKISDRGGGVPLRIIDRL 306 L L L +NA+R T S LG+ + + +SD G GVP + + Sbjct: 155 RLAQTLDHLVENALRQTPPGGRVTLS-----ARRALGE--VRLDVSDTGRGVPFHVQAHI 207 Query: 307 FSYTYSTAPTPVMDNSRNAPLAGFGYGLPISRLYAKYFQGDLNLYSLSGYGT 358 F G G GL + + + G + L S G G+ Sbjct: 208 FDRFV------------GRDRGGPGLGLALVKALVELHGGWVALESEPGNGS 247 >6BLK-C nrPDB Length = 158 Score = 48.5 bits (114), Expect = 5e-06, Method: Composition-based stats. Identities = 24/114 (21%), Positives = 41/114 (35%), Gaps = 14/114 (12%) Query: 238 PIHIVYVPSHLHHMLFELFKNAMRATVEHQENQPSLTPIEVIVVLGKEDLTIKISDRGGG 297 P ++ S L + + NA + + L I+ G +L I +D+G G Sbjct: 37 PWQVIGDSSGLGRAVLNVLDNAAKWSPPGGRVGVRLYQID----PGHAELVI--TDQGPG 90 Query: 298 VPLRIIDRLFSYTYSTAPTPVMDNSRNAPLAGFGYGLPISRLYAKYFQGDLNLY 351 +P + +F + +A M S G GL I + G L + Sbjct: 91 IPPQERHLVFERFFRSASARSMPGS--------GLGLAIVKQVVLKHGGALRVD 136 >1R62-A nrPDB Length = 160 Score = 47.4 bits (111), Expect = 1e-05, Method: Composition-based stats. Identities = 31/134 (23%), Positives = 50/134 (37%), Gaps = 18/134 (13%) Query: 235 PDQPIHIVYVPSHLHHMLFELFKNAMRA-TVEHQENQPSLTPIEVIVVLGKE---DLTIK 290 P P + + P + +L + +NA++A E E + + G+ I Sbjct: 37 PSLP-ELAHDPDQIEQVLLNIVRNALQALGPEGGEIILRTRTAFQLTLHGERYRLAARID 95 Query: 291 ISDRGGGVPLRIIDRLFSYTYSTAPTPVMDNSRNAPLAGFGYGLPISRLYAKYFQGDLNL 350 + D G G+P + D LF S G G GL I+R G + Sbjct: 96 VEDNGPGIPPHLQDTLFYPMVSGRE------------GGTGLGLSIARNLIDQHSGKIEF 143 Query: 351 YSLSGYGTDAIIYL 364 S G+ T+ +YL Sbjct: 144 TSWPGH-TEFSVYL 156 >6DK7-A nrPDB Length = 227 Score = 46.2 bits (108), Expect = 3e-05, Method: Composition-based stats. Identities = 36/166 (21%), Positives = 63/166 (37%), Gaps = 17/166 (10%) Query: 199 DVVAVVQDAFECSRMLCDQYYLSSPELKLTQVNGKFPDQPIHIVYVPSHLHHMLFELFKN 258 D+ A+++D + R+ +Q ++ ++ P P I P+ L ++ L N Sbjct: 74 DLNALIEDCLDIFRVKAEQQ-------RIELISFTQPQVPRVIGGDPTRLRQVVLSLLDN 126 Query: 259 AMRATVEHQENQPSLTPIEVIVVLGKEDLTIKISDRGGGVPLRIIDRLFSYTYSTAPTPV 318 A + T E + L + + L I + D G + + L TA Sbjct: 127 AFKQTEEGE----ILLVVALDDQGETPRLRIAVQDSGHPFDAKEREALL-----TAELHS 177 Query: 319 MDNSRNAPLAGFGYGLPISRLYAKYFQGDLNLYSLSGYGTDAIIYL 364 D + L G GL I+R + G+ + S S GT + L Sbjct: 178 GDFLSASKL-GSHLGLIIARQLVRLMGGEFGIQSGSSQGTTLSLTL 222 >1ID0-A nrPDB Length = 152 Score = 42.8 bits (99), Expect = 3e-04, Method: Composition-based stats. Identities = 23/111 (20%), Positives = 42/111 (37%), Gaps = 19/111 (17%) Query: 238 PIHIVYVPSHLHHMLFELFKNAMRATVEHQENQPSLTPIEVIVVLGKEDLTIKISDRGGG 297 I V + ++ + NA + +E +E+ E L I + D G G Sbjct: 35 EISFVGEQNDFVEVMGNVLDNACKYCLEF---------VEISARQTDEHLYIVVEDDGPG 85 Query: 298 VPLRIIDRLFSYTYSTAPTPVMDNSRNAPLAGFGYGLPISRLYAKYFQGDL 348 +PL + +F +D R G G GL ++R + ++G + Sbjct: 86 IPLSKREVIFDR------GQRVDTLRP----GQGVGLAVAREITEQYEGKI 126 >1YSR-A nrPDB Length = 150 Score = 40.5 bits (93), Expect = 0.001, Method: Composition-based stats. Identities = 30/142 (21%), Positives = 51/142 (35%), Gaps = 21/142 (14%) Query: 223 PELKLTQVNGKFPDQPIHIVYVPSHLHHMLFELFKNAMRATVEHQENQPSLTPIEVIVVL 282 P+L ++ V P IV +P+ L + NA++ H +++ V Sbjct: 26 PDLDVSLV----PSPTCIIVGLPAGLRLAVDNAIANAVK----HGGATL----VQLSAVS 73 Query: 283 GKEDLTIKISDRGGGVPLRIIDRLFSYTYSTAPTPVMDNSRNAPLAGFGYGLPISRLYAK 342 + + I I D G GVP +F A +G G GL + A+ Sbjct: 74 SRAGVEIAIDDNGSGVPEGERQVVFERFSR---------GSTASHSGSGLGLALVAQQAQ 124 Query: 343 YFQGDLNLYSLSGYGTDAIIYL 364 G +L + G ++ L Sbjct: 125 LHGGTASLENSPLGGARLVLRL 146 >3CGZ-A nrPDB Length = 157 Score = 38.1 bits (87), Expect = 0.007, Method: Composition-based stats. Identities = 24/120 (20%), Positives = 41/120 (34%), Gaps = 22/120 (18%) Query: 238 PIHIVYVPSHLHHMLFELFKNAMRATVEHQENQPSLTPIEVIVVLGKEDLTIKISDRGGG 297 I V + ++ + NA + +E +E+ + L I + D G G Sbjct: 40 EISFVGEQNDFVEVMGNVLDNACKYCLEF---------VEISARQTDDHLHIFVEDDGPG 90 Query: 298 VPLRIIDRLFSYTYSTAPTPVMDNSRNAPLA-GFGYGLPISRLYAKYFQGDLNL-YSLSG 355 +P +F R L G G GL ++R + + G + SL G Sbjct: 91 IPHSKRSLVFDR-----------GQRADTLRPGQGVGLAVAREITEQYAGQIIASDSLLG 139 >1MX0-A nrPDB Length = 472 Score = 37.8 bits (86), Expect = 0.009, Method: Composition-based stats. Identities = 19/99 (19%), Positives = 42/99 (42%), Gaps = 8/99 (8%) Query: 248 LHHMLFELFKNAMRATVEHQENQPSLTPIEVIVVLGKEDLTIKISDRGGGVPLRIIDRLF 307 L+ + EL +N++ AT + P++ ++ ++ + + D G G+P + + F Sbjct: 34 LYQTVRELIENSLDAT-DVHGILPNIKITIDLIDDARQIYKVNVVDNGIGIPPQEVPNAF 92 Query: 308 SY-TYSTAPTPVMDNSRNAPLAGFGYGLPISRLYAKYFQ 345 YS+ +G G+ + LY++ Q Sbjct: 93 GRVLYSSKYVNRQTRGM------YGLGVKAAVLYSQMHQ 125 >2ZBK-B nrPDB Length = 530 Score = 37.8 bits (86), Expect = 0.010, Method: Composition-based stats. Identities = 19/99 (19%), Positives = 42/99 (42%), Gaps = 8/99 (8%) Query: 248 LHHMLFELFKNAMRATVEHQENQPSLTPIEVIVVLGKEDLTIKISDRGGGVPLRIIDRLF 307 L+ + EL +N++ AT + P++ ++ ++ + + D G G+P + + F Sbjct: 32 LYQTVRELIENSLDAT-DVHGILPNIKITIDLIDDARQIYKVNVVDNGIGIPPQEVPNAF 90 Query: 308 SY-TYSTAPTPVMDNSRNAPLAGFGYGLPISRLYAKYFQ 345 YS+ +G G+ + LY++ Q Sbjct: 91 GRVLYSSKYVNRQTRGM------YGLGVKAAVLYSQMHQ 123 >5IDM-A nrPDB Length = 179 Score = 37.4 bits (85), Expect = 0.013, Method: Composition-based stats. Identities = 19/84 (22%), Positives = 34/84 (40%), Gaps = 10/84 (11%) Query: 281 VLGKEDLTIKISDRGGGVPLRIIDRLFSYTYSTAPTPVMDNSRNAPLAGFGYGLPISRLY 340 + I++SD G G+P ++ ++F ++T P G G GL Sbjct: 90 AADGDTAFIEVSDDGPGIPPDVMGKIFDPFFTTKPVGE----------GTGLGLATVYGI 139 Query: 341 AKYFQGDLNLYSLSGYGTDAIIYL 364 K G ++++S G I+L Sbjct: 140 VKQSDGWIHVHSRPNEGAAFRIFL 163 >5IDJ-A nrPDB Length = 242 Score = 37.4 bits (85), Expect = 0.013, Method: Composition-based stats. Identities = 19/84 (22%), Positives = 34/84 (40%), Gaps = 10/84 (11%) Query: 281 VLGKEDLTIKISDRGGGVPLRIIDRLFSYTYSTAPTPVMDNSRNAPLAGFGYGLPISRLY 340 + I++SD G G+P ++ ++F ++T P G G GL Sbjct: 164 AADGDTAFIEVSDDGPGIPPDVMGKIFDPFFTTKPVGE----------GTGLGLATVYGI 213 Query: 341 AKYFQGDLNLYSLSGYGTDAIIYL 364 K G ++++S G I+L Sbjct: 214 VKQSDGWIHVHSRPNEGAAFRIFL 237 >3JZ3-A nrPDB Length = 222 Score = 36.6 bits (83), Expect = 0.019, Method: Composition-based stats. Identities = 22/103 (21%), Positives = 37/103 (35%), Gaps = 20/103 (19%) Query: 258 NAMRATVEHQENQPSLTPIEVIVVLGKEDLTIKISDRGGGVPLRIIDRLFSYTYSTAPTP 317 NA+R + + V V L ++ ++ D G GV + R+ Y Sbjct: 128 NAVRYSPQGS---------VVDVTLNADNFIVR--DNGPGVTPEALARIGERFYR----- 171 Query: 318 VMDNSRNAPLAGFGYGLPISRLYAKYFQGDLNLYSLSGYGTDA 360 + A G G GL I + AK ++ + G +A Sbjct: 172 --PPGQTA--TGSGLGLSIVQRIAKLHGMNVEFGNAEQGGFEA 210 >4JPB-A nrPDB Length = 319 Score = 35.5 bits (80), Expect = 0.050, Method: Composition-based stats. Identities = 27/140 (19%), Positives = 52/140 (37%), Gaps = 33/140 (23%) Query: 252 LFELFKNAMRATVEHQENQPSL--TPIEVIVVL---GKEDLTIKISDRGGGVPLRIIDRL 306 L L +NA+ +E +E + + PI +++ ++ I++ D G G+ I R Sbjct: 52 LLHLLRNAIDHGIEPKEERIAKGKPPIGTLILSARHEGNNVVIEVEDDGRGIDKEKIIR- 110 Query: 307 FSYTYSTAPTPVMDNSRNAPLA----------------------GFGYGLPISRLYAKYF 344 ++D S+ A L+ G G G+ + + + Sbjct: 111 -----KAIEKGLIDESKAATLSDQEILNFLVPGFSTKEKVSEVSGRGVGMDVVKNVVESL 165 Query: 345 QGDLNLYSLSGYGTDAIIYL 364 G +++ S GT I L Sbjct: 166 NGSISIESEKDKGTKVTIRL 185 >1I5D-A nrPDB Length = 191 Score = 35.1 bits (79), Expect = 0.063, Method: Composition-based stats. Identities = 23/138 (16%), Positives = 53/138 (38%), Gaps = 28/138 (20%) Query: 252 LFELFKNAMRATVEHQENQPSL--TPIEVIVVL---GKEDLTIKISDRGGGVPLRIIDR- 305 L L +NA+ +E +E + + PI +++ ++ I++ D G G+ I R Sbjct: 54 LLHLLRNAIDHGIEPKEERIAKGKPPIGTLILSARHEGNNVVIEVEDDGRGIDKEKIIRK 113 Query: 306 -------------------LFSYTYSTAPTPVMDNSRNAPLAGFGYGLPISRLYAKYFQG 346 + ++ + + + + ++G G G+ + + + G Sbjct: 114 AIEKGLIDESKAATLSDQEILNFLFVPGFST---KEKVSEVSGRGVGMDVVKNVVESLNG 170 Query: 347 DLNLYSLSGYGTDAIIYL 364 +++ S GT I L Sbjct: 171 SISIESEKDKGTKVTIRL 188 >4XIV-A nrPDB Length = 252 Score = 34.7 bits (78), Expect = 0.071, Method: Composition-based stats. Identities = 23/138 (16%), Positives = 53/138 (38%), Gaps = 28/138 (20%) Query: 252 LFELFKNAMRATVEHQENQPSL--TPIEVIVVL---GKEDLTIKISDRGGGVPLRIIDR- 305 L L +NA+ +E +E + + PI +++ ++ I++ D G G+ I R Sbjct: 115 LLHLLRNAIDHGIEPKEERIAKGKPPIGTLILSARHEGNNVVIEVEDDGRGIDKEKIIRK 174 Query: 306 -------------------LFSYTYSTAPTPVMDNSRNAPLAGFGYGLPISRLYAKYFQG 346 + ++ + + + + ++G G G+ + + + G Sbjct: 175 AIEKGLIDESKAATLSDQEILNFLFVPGFST---KEKVSEVSGRGVGMDVVKNVVESLNG 231 Query: 347 DLNLYSLSGYGTDAIIYL 364 +++ S GT I L Sbjct: 232 SISIESEKDKGTKVTIRL 249 >3JA6-C nrPDB Length = 379 Score = 34.3 bits (77), Expect = 0.11, Method: Composition-based stats. Identities = 23/138 (16%), Positives = 52/138 (37%), Gaps = 28/138 (20%) Query: 252 LFELFKNAMRATVEHQENQPSL--TPIEVIVVL---GKEDLTIKISDRGGGVPLRIIDR- 305 L L +NA+ +E +E + + PI +++ ++ I++ D G G+ I R Sbjct: 111 LLHLLRNAIDHGIEPKEERIAKGKPPIGTLILSARHEGNNVVIEVEDDGRGIDKEKIIRK 170 Query: 306 -------------------LFSYTYSTAPTPVMDNSRNAPLAGFGYGLPISRLYAKYFQG 346 + ++ + + + + ++G G G+ + + + G Sbjct: 171 AIEKGLIDESKAATLSDQEILNFLFVPGFST---KEKVSEVSGRGVGMDVVKNVVESLNG 227 Query: 347 DLNLYSLSGYGTDAIIYL 364 + + S GT I L Sbjct: 228 SMGIESEKDKGTKVTIRL 245 >4KP4-A nrPDB Length = 236 Score = 33.1 bits (74), Expect = 0.21, Method: Composition-based stats. Identities = 21/119 (17%), Positives = 34/119 (28%), Gaps = 17/119 (14%) Query: 239 IHIVYVPSHLHHMLFELFKNAMRATVEHQENQPSLTPIEVIVVLGKEDLTIKISDRGGGV 298 I + P + + + NA R + P ++ D G G+ Sbjct: 114 IEVKMHPLSIKRAVANMVVNAARYGNGWIKVSSGTEPNRA---------WFQVEDDGPGI 164 Query: 299 PLRIIDRLFSYTYSTAPTPVMDNSRNAPLAGFGYGLPISRLYAKYFQGDLNLYSLSGYG 357 LF P + ++G G GL I + G L L + G Sbjct: 165 APEQRKHLF--------QPFVRGDSARTISGTGLGLAIVQRIVDNHNGMLELGTSERGG 215 >4CTI-A nrPDB Length = 273 Score = 33.1 bits (74), Expect = 0.21, Method: Composition-based stats. Identities = 21/119 (17%), Positives = 34/119 (28%), Gaps = 17/119 (14%) Query: 239 IHIVYVPSHLHHMLFELFKNAMRATVEHQENQPSLTPIEVIVVLGKEDLTIKISDRGGGV 298 I + P + + + NA R + P ++ D G G+ Sbjct: 151 IEVKMHPLSIKRAVANMVVNAARYGNGWIKVSSGTEPNRA---------WFQVEDDGPGI 201 Query: 299 PLRIIDRLFSYTYSTAPTPVMDNSRNAPLAGFGYGLPISRLYAKYFQGDLNLYSLSGYG 357 LF P + ++G G GL I + G L L + G Sbjct: 202 APEQRKHLF--------QPFVRGDSARTISGTGLGLAIVQRIVDNHNGMLELGTSERGG 252 >1BXD-A nrPDB Length = 161 Score = 33.1 bits (74), Expect = 0.21, Method: Composition-based stats. Identities = 21/119 (17%), Positives = 34/119 (28%), Gaps = 17/119 (14%) Query: 239 IHIVYVPSHLHHMLFELFKNAMRATVEHQENQPSLTPIEVIVVLGKEDLTIKISDRGGGV 298 I + P + + + NA R + P ++ D G G+ Sbjct: 39 IEVKMHPLSIKRAVANMVVNAARYGNGWIKVSSGTEPNRA---------WFQVEDDGPGI 89 Query: 299 PLRIIDRLFSYTYSTAPTPVMDNSRNAPLAGFGYGLPISRLYAKYFQGDLNLYSLSGYG 357 LF P + ++G G GL I + G L L + G Sbjct: 90 APEQRKHLF--------QPFVRGDSARTISGTGLGLAIVQRIVDNHNGMLELGTSERGG 140 >5CPH-A nrPDB Length = 212 Score = 33.1 bits (74), Expect = 0.22, Method: Composition-based stats. Identities = 18/59 (30%), Positives = 36/59 (61%), Gaps = 8/59 (13%) Query: 248 LHHMLFELFKNAMRATVEHQENQPSLTPIEVIVVLGKEDLTIKISDRGGGVPLRIIDRL 306 LHH+++E+ N++ + NQ IEV++ ++D IK++D G G+P+ I +++ Sbjct: 45 LHHLVWEIVDNSIDEALAGYANQ-----IEVVI---EKDNWIKVTDNGRGIPVDIQEKM 95 >4URM-A nrPDB Length = 231 Score = 33.1 bits (74), Expect = 0.22, Method: Composition-based stats. Identities = 18/59 (30%), Positives = 36/59 (61%), Gaps = 8/59 (13%) Query: 248 LHHMLFELFKNAMRATVEHQENQPSLTPIEVIVVLGKEDLTIKISDRGGGVPLRIIDRL 306 LHH+++E+ N++ + NQ IEV++ ++D IK++D G G+P+ I +++ Sbjct: 44 LHHLVWEIVDNSIDEALAGYANQ-----IEVVI---EKDNWIKVTDNGRGIPVDIQEKM 94 >5MMP-A nrPDB Length = 234 Score = 32.4 bits (72), Expect = 0.42, Method: Composition-based stats. Identities = 18/67 (26%), Positives = 31/67 (46%), Gaps = 8/67 (11%) Query: 233 KFPDQPIHIVYVPSHLHHMLFELFKNAMRATVEHQENQPSLTPIEVIVVLGKEDLTIKIS 292 K P I + LHHM+FE+ NA+ + E+IV + ++ ++ + Sbjct: 35 KRPGMYIGDTDDGTGLHHMVFEVVDNAIDEALAGHCK-------EIIVTIHADN-SVSVQ 86 Query: 293 DRGGGVP 299 D G G+P Sbjct: 87 DDGRGIP 93 >4PU9-A nrPDB Length = 398 Score = 32.4 bits (72), Expect = 0.42, Method: Composition-based stats. Identities = 18/67 (26%), Positives = 31/67 (46%), Gaps = 8/67 (11%) Query: 233 KFPDQPIHIVYVPSHLHHMLFELFKNAMRATVEHQENQPSLTPIEVIVVLGKEDLTIKIS 292 K P I + LHHM+FE+ NA+ + E+IV + ++ ++ + Sbjct: 27 KRPGMYIGDTDDGTGLHHMVFEVVDNAIDEALAGHCK-------EIIVTIHADN-SVSVQ 78 Query: 293 DRGGGVP 299 D G G+P Sbjct: 79 DDGRGIP 85 >4XEM-A nrPDB Length = 475 Score = 30.8 bits (68), Expect = 1.2, Method: Composition-based stats. Identities = 10/16 (62%), Positives = 12/16 (75%) Query: 332 YGLPISRLYAKYFQGD 347 +G+PI RLY YF GD Sbjct: 146 FGIPIERLYVTYFGGD 161 >1XRE-A nrPDB Length = 217 Score = 30.4 bits (67), Expect = 1.5, Method: Composition-based stats. Identities = 14/44 (31%), Positives = 21/44 (47%), Gaps = 1/44 (2%) Query: 291 ISDRGGGVPLRIIDRLFSYTYSTAPTPVMDNSRNA-PLAGFGYG 333 +S RGGG P + ++ Y ++T S+ A G GYG Sbjct: 99 MSPRGGGEPNGDVAKVIDYYFNTFDNLKDQLSKAAISRFGSGYG 142 >4OKD-A nrPDB Length = 840 Score = 29.3 bits (64), Expect = 3.2, Method: Composition-based stats. Identities = 12/33 (36%), Positives = 19/33 (57%) Query: 363 YLKALSSESIEKLPVFNKSAFKHYQMSSEADDW 395 YLK+L +IE LPVF + ++Y +D + Sbjct: 257 YLKSLGVNAIELLPVFEFNELEYYSQIPGSDQY 289 >4RLP-A nrPDB Length = 288 Score = 29.3 bits (64), Expect = 3.4, Method: Composition-based stats. Identities = 18/90 (20%), Positives = 36/90 (40%), Gaps = 8/90 (8%) Query: 94 QSLMDLVEFH--EKSPDDQKALSDFVDTL------IKVRNRHHNVVPTMAQGIIEYKDAC 145 Q + L +F ++S D F T+ I +R+ H+ V + G + Y Sbjct: 145 QGHVKLTDFGLCKESIHDGTVTHTFCGTIEYMAPEILMRSGHNRAVDWWSLGALMYDMLT 204 Query: 146 TVDPVTNQNLQYFLDRFYMNRISTRMLMNQ 175 P T +N + +D+ +++ + Q Sbjct: 205 GAPPFTGENRKKTIDKILKCKLNLPPYLTQ 234 >4L42-A nrPDB Length = 346 Score = 29.3 bits (64), Expect = 3.4, Method: Composition-based stats. Identities = 18/90 (20%), Positives = 36/90 (40%), Gaps = 8/90 (8%) Query: 94 QSLMDLVEFH--EKSPDDQKALSDFVDTL------IKVRNRHHNVVPTMAQGIIEYKDAC 145 Q + L +F ++S D F T+ I +R+ H+ V + G + Y Sbjct: 158 QGHVKLTDFGLCKESIHDGTVTHTFCGTIEYMAPEILMRSGHNRAVDWWSLGALMYDMLT 217 Query: 146 TVDPVTNQNLQYFLDRFYMNRISTRMLMNQ 175 P T +N + +D+ +++ + Q Sbjct: 218 GAPPFTGENRKKTIDKILKCKLNLPPYLTQ 247 >1TID-A nrPDB Length = 136 Score = 29.3 bits (64), Expect = 3.4, Method: Composition-based stats. Identities = 19/108 (17%), Positives = 38/108 (35%), Gaps = 16/108 (14%) Query: 255 LFKNAMRATVEHQENQPSLTPIEVIVVLGKEDLTIKISDRGGGVPLRIIDRLFSYTYSTA 314 + A+ + H N + + V++ + + + D G G+P I+ ++T Sbjct: 43 VVSEAVTNAIIHGYNNDPNGIVSISVIIEDGVVHLTVRDEGVGIP--DIEEARQPLFTTK 100 Query: 315 PTPVMDNSRNAPLAGFGYGLPISRLYAKYFQGDLNLYSLSGYGTDAII 362 P L G G I + F ++ + S GT + Sbjct: 101 PE----------LERSGMGFTI----MENFMDEVIVESEVNKGTTVYL 134 >1OR4-A nrPDB Length = 178 Score = 28.9 bits (63), Expect = 4.6, Method: Composition-based stats. Identities = 11/51 (21%), Positives = 24/51 (47%), Gaps = 4/51 (7%) Query: 85 VQLVKSWYIQSLMDLV----EFHEKSPDDQKALSDFVDTLIKVRNRHHNVV 131 + L+ WY+ + +L+ + +E S +Q+ L + K+ N +V Sbjct: 126 IGLLPKWYMGAFQELLLSMIDIYEASITNQQELLKAIKATTKILNLEQQLV 176 >5GUP-v nrPDB Length = 453 Score = 28.5 bits (62), Expect = 4.8, Method: Composition-based stats. Identities = 22/135 (16%), Positives = 48/135 (35%), Gaps = 23/135 (17%) Query: 221 SSPELKLTQVNG-KFPDQPIHIVYVPSHLHHMLFELFKNAMRATVEHQENQPSL-----T 274 ++PE + +V + + V + +L L A R + + P T Sbjct: 142 AAPEFRRWEVAALQSQLRIDKAVAFQNPQAQVLENLHAAAYRNALANSLYCPDYRIGKVT 201 Query: 275 PIEVIVVLGKEDLTIKISDRGGGVPLRIIDRLFSYTYSTAPTPVMDNSRNAPLAGFGYGL 334 P ++ + + +++ G GV ++ ++ + + G GL Sbjct: 202 PDQLHYYVQNHFTSARMALIGLGVSHPVLKQVAERFLN--------------MRG---GL 244 Query: 335 PISRLYAKYFQGDLN 349 +S AKY G++ Sbjct: 245 GLSGAKAKYRGGEIR 259 >2VCE-A nrPDB Length = 480 Score = 28.5 bits (62), Expect = 5.3, Method: Composition-based stats. Identities = 13/39 (33%), Positives = 24/39 (61%) Query: 248 LHHMLFELFKNAMRATVEHQENQPSLTPIEVIVVLGKED 286 L + FEL NA++A E ++P + P+ +V +GK++ Sbjct: 211 LVNTFFELEPNAIKALQEPGLDKPPVYPVGPLVNIGKQE 249 >2OTN-A nrPDB Length = 308 Score = 28.5 bits (62), Expect = 6.0, Method: Composition-based stats. Identities = 11/35 (31%), Positives = 20/35 (57%) Query: 264 VEHQENQPSLTPIEVIVVLGKEDLTIKISDRGGGV 298 +E E P +E I +L +E++ ++ +RG GV Sbjct: 208 LETHEMFPERVNVEFIEILNEEEMNFRVWERGSGV 242 >4HZ5-A nrPDB Length = 216 Score = 28.5 bits (62), Expect = 6.2, Method: Composition-based stats. Identities = 15/52 (28%), Positives = 29/52 (55%), Gaps = 8/52 (15%) Query: 248 LHHMLFELFKNAMRATVEHQENQPSLTPIEVIVVLGKEDLTIKISDRGGGVP 299 LHH+++E+ NA+ + S E+ V + K++ +I ++D G G+P Sbjct: 22 LHHLVYEIVDNAV-------DEALSGYGNEINVTIQKDN-SICVADSGRGMP 65 >5SZL-A nrPDB Length = 427 Score = 28.1 bits (61), Expect = 6.4, Method: Composition-based stats. Identities = 19/67 (28%), Positives = 34/67 (50%), Gaps = 8/67 (11%) Query: 176 HILIFSDSQTGNPSHIGSIDPNCDVVAVVQDAFECSRMLCDQYYLSSPE-----LKLTQV 230 H L+ + S G+P H G++ + VV V + ++ +Y++S PE +L +V Sbjct: 180 HYLVLTASDGGSPIHSGTLQIHVQVVDVNDNPPAFTKA---EYHVSVPENVPLGTRLLKV 236 Query: 231 NGKFPDQ 237 N PD+ Sbjct: 237 NATDPDE 243 >4ZI9-A nrPDB Length = 318 Score = 28.1 bits (61), Expect = 6.4, Method: Composition-based stats. Identities = 19/67 (28%), Positives = 34/67 (50%), Gaps = 8/67 (11%) Query: 176 HILIFSDSQTGNPSHIGSIDPNCDVVAVVQDAFECSRMLCDQYYLSSPE-----LKLTQV 230 H L+ + S G+P H G++ + VV V + ++ +Y++S PE +L +V Sbjct: 181 HYLVLTASDGGSPIHSGTLQIHVQVVDVNDNPPAFTKA---EYHVSVPENVPLGTRLLKV 237 Query: 231 NGKFPDQ 237 N PD+ Sbjct: 238 NATDPDE 244 >4YRY-B nrPDB Length = 468 Score = 28.1 bits (61), Expect = 7.3, Method: Composition-based stats. Identities = 8/54 (14%), Positives = 22/54 (40%) Query: 146 TVDPVTNQNLQYFLDRFYMNRISTRMLMNQHILIFSDSQTGNPSHIGSIDPNCD 199 V + + + L+ + + L++++ +F + G P +G N + Sbjct: 196 EVSYIRKLGVNFHLNTVVGKTVKVKELLSEYDAVFIGTGAGTPKFMGIPGTNLN 249 >4YIR-X nrPDB Length = 171 Score = 27.7 bits (60), Expect = 8.3, Method: Composition-based stats. Identities = 13/52 (25%), Positives = 23/52 (44%) Query: 227 LTQVNGKFPDQPIHIVYVPSHLHHMLFELFKNAMRATVEHQENQPSLTPIEV 278 L ++ ++P HI+ P ML E + M+ +E ++ IEV Sbjct: 53 LENISARYPQLREHIMANPEVFVSMLLEAVGDNMQDVMEGADDMVEGEDIEV 104 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.311 0.132 0.361 Lambda K H 0.267 0.0405 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 15,828,011 Number of Sequences: 36641 Number of extensions: 632304 Number of successful extensions: 1742 Number of sequences better than 10.0: 53 Number of HSP's better than 10.0 without gapping: 32 Number of HSP's successfully gapped in prelim test: 49 Number of HSP's that attempted gapping in prelim test: 1667 Number of HSP's gapped (non-prelim): 81 length of query: 411 length of database: 10,336,785 effective HSP length: 99 effective length of query: 312 effective length of database: 6,709,326 effective search space: 2093309712 effective search space used: 2093309712 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 60 (27.7 bits)