BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q16222 (522 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 1JV1-A nrPDB 1042 0.0 1VM8-A nrPDB 1022 0.0 4BMA-A nrPDB 416 e-116 2YQJ-A nrPDB 340 1e-93 3OC9-A nrPDB 253 2e-67 4BQH-A nrPDB 252 3e-67 3R2W-A nrPDB 55 1e-07 2I5K-A nrPDB 46 4e-05 3GUE-A nrPDB 45 9e-05 4M2B-A nrPDB 39 0.004 3OH0-A nrPDB 35 0.065 4NAK-A nrPDB 32 0.98 6DTT-A nrPDB 30 2.5 4V7H-AC nrPDB 30 2.7 4BSZ-A nrPDB 30 3.4 4XAX-A nrPDB 29 5.7 3RR5-A nrPDB 28 6.5 3K92-A nrPDB 28 8.9 >1JV1-A nrPDB Length = 505 Score = 1042 bits (2694), Expect = 0.0, Method: Compositional matrix adjust. Identities = 505/522 (96%), Positives = 505/522 (96%), Gaps = 17/522 (3%) Query: 1 MNINDLKLTLSKAGQEHLLRFWNELEEAQQVELYAELQAMNFEELNFFFQKAIEGFNQSS 60 MNINDLKLTLSKAGQEHLLRFWNELEEAQQVELYAELQAMNFEELNFFFQKAIEGFNQSS Sbjct: 1 MNINDLKLTLSKAGQEHLLRFWNELEEAQQVELYAELQAMNFEELNFFFQKAIEGFNQSS 60 Query: 61 HQKNVDARMEPVPREVLGSATRDQDQLQAWESEGLFQISQNKVAVLLLAGGQGTRLGVAY 120 HQKNVDARMEPVPREVLGSATRDQDQLQAWESEGLFQISQNKVAVLLLAGGQGTRLGVAY Sbjct: 61 HQKNVDARMEPVPREVLGSATRDQDQLQAWESEGLFQISQNKVAVLLLAGGQGTRLGVAY 120 Query: 121 PKGMYDVGLPSRKTLFQIQAERILKLQQVAEKYYGNKCIIPWYIMTSGRTMESTKEFFTK 180 PKGMYDVGLPSRKTLFQIQAERILKLQQVAEKYYGNKCIIPWYIMTSGRTMESTKEFFTK Sbjct: 121 PKGMYDVGLPSRKTLFQIQAERILKLQQVAEKYYGNKCIIPWYIMTSGRTMESTKEFFTK 180 Query: 181 HKYFGLKKENVIFFQQGMLPAMSFDGKIILEEKNKVSMAPDGNGGLYRALAAQNIVEDME 240 HKYFGLKKENVIFFQQGMLPAMSFDGKIILEEKNKVSMAPDGNGGLYRALAAQNIVEDME Sbjct: 181 HKYFGLKKENVIFFQQGMLPAMSFDGKIILEEKNKVSMAPDGNGGLYRALAAQNIVEDME 240 Query: 241 QRGIWSIHVYCVDNILVKVADPRFIGFCIQKGADCGAKVVEKTNPTEPVGVVCRVDGVYQ 300 QRGIWSIHVYCVDNILVKVADPRFIGFCIQKGADCGAKVVEKTNPTEPVGVVCRVDGVYQ Sbjct: 241 QRGIWSIHVYCVDNILVKVADPRFIGFCIQKGADCGAKVVEKTNPTEPVGVVCRVDGVYQ 300 Query: 301 VVEYSEISLATAQKRSSDGRLLFNAGNIANHFFTVPFLRDVVNVYEPQLQHHVAQKKIPY 360 VVEYSEISLATAQKRSSDGRLLFNAGNIANHFFTVPFLRDVVNVYEPQLQHHVAQKKIPY Sbjct: 301 VVEYSEISLATAQKRSSDGRLLFNAGNIANHFFTVPFLRDVVNVYEPQLQHHVAQKKIPY 360 Query: 361 VDTQGQLIKPDKPNGIKMEKFVFDIFQFAKKFVVYEVLREDEFSPLKNADSQNGKDNPTT 420 VDTQGQLIKPDKPNGIKMEKFVFDIFQFAKKFVVYEVLREDEFSPLKNADSQNGKDNPTT Sbjct: 361 VDTQGQLIKPDKPNGIKMEKFVFDIFQFAKKFVVYEVLREDEFSPLKNADSQNGKDNPTT 420 Query: 421 ARHALMSLHHCWVLNAGGHFIDENGSRLPAIPRSATNGKSETITADVNHNLKDANDVPIQ 480 ARHALMSLHHCWVLNAGGHFIDENGSRLPAIPR LKDANDVPIQ Sbjct: 421 ARHALMSLHHCWVLNAGGHFIDENGSRLPAIPR-----------------LKDANDVPIQ 463 Query: 481 CEISPLISYAGEGLESYVADKEFHAPLIIDENGVHELVKNGI 522 CEISPLISYAGEGLESYVADKEFHAPLIIDENGVHELVKNGI Sbjct: 464 CEISPLISYAGEGLESYVADKEFHAPLIIDENGVHELVKNGI 505 >1VM8-A nrPDB Length = 534 Score = 1022 bits (2642), Expect = 0.0, Method: Compositional matrix adjust. Identities = 487/522 (93%), Positives = 506/522 (96%) Query: 1 MNINDLKLTLSKAGQEHLLRFWNELEEAQQVELYAELQAMNFEELNFFFQKAIEGFNQSS 60 MN+NDLK LS+AGQEHLL+FWNEL EAQQ+ELY ELQAMNFEELN FF+KAI F++SS Sbjct: 13 MNVNDLKQRLSQAGQEHLLQFWNELSEAQQMELYMELQAMNFEELNSFFRKAIGEFDRSS 72 Query: 61 HQKNVDARMEPVPREVLGSATRDQDQLQAWESEGLFQISQNKVAVLLLAGGQGTRLGVAY 120 HQ+ VDARMEPVPR+VLGSATRDQ+QLQAWESEGL QISQNKVAVLLLAGGQGTRLGV+Y Sbjct: 73 HQEKVDARMEPVPRQVLGSATRDQEQLQAWESEGLSQISQNKVAVLLLAGGQGTRLGVSY 132 Query: 121 PKGMYDVGLPSRKTLFQIQAERILKLQQVAEKYYGNKCIIPWYIMTSGRTMESTKEFFTK 180 PKGMYDVGLPS KTLFQIQAERILKLQQ+AEK++GNKC IPWYIMTSGRTMESTKEFFTK Sbjct: 133 PKGMYDVGLPSHKTLFQIQAERILKLQQLAEKHHGNKCTIPWYIMTSGRTMESTKEFFTK 192 Query: 181 HKYFGLKKENVIFFQQGMLPAMSFDGKIILEEKNKVSMAPDGNGGLYRALAAQNIVEDME 240 HK+FGLKKENV+FFQQGMLPAMSFDGKIILEEKNKVSMAPDGNGGLYRALAAQNIVEDME Sbjct: 193 HKFFGLKKENVVFFQQGMLPAMSFDGKIILEEKNKVSMAPDGNGGLYRALAAQNIVEDME 252 Query: 241 QRGIWSIHVYCVDNILVKVADPRFIGFCIQKGADCGAKVVEKTNPTEPVGVVCRVDGVYQ 300 QRGI SIHVYCVDNILVKVADPRFIGFCIQKGADCGAKVVEKTNPTEPVGVVCRVDGVYQ Sbjct: 253 QRGICSIHVYCVDNILVKVADPRFIGFCIQKGADCGAKVVEKTNPTEPVGVVCRVDGVYQ 312 Query: 301 VVEYSEISLATAQKRSSDGRLLFNAGNIANHFFTVPFLRDVVNVYEPQLQHHVAQKKIPY 360 VVEYSEISLATAQ+RSSDGRLLFNAGNIANHFFTVPFL+DVVNVYEPQLQHHVAQKKIPY Sbjct: 313 VVEYSEISLATAQRRSSDGRLLFNAGNIANHFFTVPFLKDVVNVYEPQLQHHVAQKKIPY 372 Query: 361 VDTQGQLIKPDKPNGIKMEKFVFDIFQFAKKFVVYEVLREDEFSPLKNADSQNGKDNPTT 420 VD+QG IKPDKPNGIKMEKFVFDIFQFAKKFVVYEVLREDEFSPLKNADSQNGKDNPTT Sbjct: 373 VDSQGYFIKPDKPNGIKMEKFVFDIFQFAKKFVVYEVLREDEFSPLKNADSQNGKDNPTT 432 Query: 421 ARHALMSLHHCWVLNAGGHFIDENGSRLPAIPRSATNGKSETITADVNHNLKDANDVPIQ 480 ARHALMSLHHCWVLNAGGHFIDENGSRLPAIPRSATNGKSE ITADVNHNLKDANDVPIQ Sbjct: 433 ARHALMSLHHCWVLNAGGHFIDENGSRLPAIPRSATNGKSEAITADVNHNLKDANDVPIQ 492 Query: 481 CEISPLISYAGEGLESYVADKEFHAPLIIDENGVHELVKNGI 522 CEISPLISYAGEGLE YVADKEFHAPLIIDENGVHELVKNGI Sbjct: 493 CEISPLISYAGEGLEGYVADKEFHAPLIIDENGVHELVKNGI 534 >4BMA-A nrPDB Length = 509 Score = 416 bits (1068), Expect = e-116, Method: Compositional matrix adjust. Identities = 229/513 (44%), Positives = 317/513 (61%), Gaps = 47/513 (9%) Query: 6 LKLTLSKAGQEHLLRFWNELEEAQQVELYAELQAMNFEELNFFFQKAIEGFNQSSHQKNV 65 L+ + AGQ H+ F +EL+ ++ +L+ +L + + +N KA+ + Sbjct: 35 LRKKYTDAGQGHVFAFVDELQTGERSQLFHQLSSFDPVRINELADKAL----NPPKADDG 90 Query: 66 DARMEPVPREVLGSATRDQD--QLQAWESEGLFQISQNKVAVLLLAGGQGTRLGVAYPKG 123 A +EP+P ++ ++ D D L+ W EGL ++ NKVAV+L+AGGQGTRLG + PKG Sbjct: 91 PASLEPLP-DIATASILDSDPKDLEQWYEEGLKLVAGNKVAVVLMAGGQGTRLGSSAPKG 149 Query: 124 MYDVGLPSRKTLFQIQAERILKLQQVAEKYYGNKCIIPWYIMTSGRTMESTKEFFTKHKY 183 +D+GLPS K+LFQIQAERI KLQ +A++ G + +IPWY+MTSG T + T+EFF +HKY Sbjct: 150 CFDIGLPSHKSLFQIQAERIAKLQLLAQRISGKEAVIPWYVMTSGPTRKPTEEFFEQHKY 209 Query: 184 FGLKKENVIFFQQGMLPAMSFDGKIILEEKNKVSMAPDGNGGLYRALAAQNIVEDMEQRG 243 FGL K +VI F+QG+LP +S +GKI++E K KV++APDGNGG+Y+AL + EDM +RG Sbjct: 210 FGLNKSDVIIFEQGVLPCISNEGKILMESKFKVAVAPDGNGGIYQALLTSGVREDMRKRG 269 Query: 244 IWSIHVYCVDNILVKVADPRFIGFCIQKGADCGAKVVEKTNPTEPVGVVCRVDGVYQVVE 303 I IH YCVDN LVKVADP FIGF K D KVV K N TE VG++ + +G VVE Sbjct: 270 IEHIHTYCVDNCLVKVADPVFIGFAASKQVDIATKVVRKRNATESVGLILQKNGKPDVVE 329 Query: 304 YSEISLATAQKRSSD--GRLLFNAGNIANHFFTVPFLRDVVNVYEPQLQHHVAQKKIPYV 361 YSEI TA+ + L F A NI NH+++ F + + ++ +L HHVA+KKIP + Sbjct: 330 YSEIDKETAEAKDPKQPDVLKFRAANIVNHYYSFKFF-ESIELWAHKLPHHVARKKIPCI 388 Query: 362 -DTQGQLIKPDKPNGIKMEKFVFDIFQFA--KKFVVYEVLREDEFSPLKNADSQNGKDNP 418 + G+ KP+KPNGIK+E+FVFD+F +KF EV REDEFSPLKNA G+D+P Sbjct: 389 KEGTGEFFKPEKPNGIKLEQFVFDVFPMTPLEKFACIEVRREDEFSPLKNARG-TGEDDP 447 Query: 419 TTARHALMSLHHCWVLNAGGHFIDENGSRLPAIPRSATNGKSETITADVNHNLKDANDVP 478 T++ +MS W+ AGG I E DV Sbjct: 448 DTSKRDIMSQGQRWIEKAGGIVITE---------------------GDV----------- 475 Query: 479 IQCEISPLISYAGEGLESYVADKEFHAPLIIDE 511 + E+SPLISY GEGLE ++ +E AP I++ Sbjct: 476 VGVEVSPLISYGGEGLE-FLKGREIKAPAFIEK 507 >2YQJ-A nrPDB Length = 486 Score = 340 bits (871), Expect = 1e-93, Method: Compositional matrix adjust. Identities = 199/452 (44%), Positives = 270/452 (59%), Gaps = 21/452 (4%) Query: 9 TLSKAGQEHLLRFWNELEEAQQVELYAELQAMNFEELNFFFQKAIEGFNQSSHQKNVDAR 68 + +A Q+ L ++++ L QQ E +L + EE +E Q S + Sbjct: 12 SFKQANQDQLFQYYDSLTIDQQQEFIDQLSTI--EEPAKLI-STVEQAIQFSQTNSTSRN 68 Query: 69 MEPVPREVLGSATR-DQDQLQAWESEGLFQISQNKVAVLLLAGGQGTRLGVAYPKGMYDV 127 +P E S +D LQ W GL I +VAVLL+AGGQGTRLG + PKG +++ Sbjct: 69 FTQLPNEQTASTLDLSKDILQNWTELGLKAIGNGEVAVLLMAGGQGTRLGSSAPKGCFNI 128 Query: 128 GLPSRKTLFQIQAERILKLQQVAEKYYGN--KCIIPWYIMTSGRTMESTKEFFTKHKYFG 185 LPS+K+LFQIQAE+ILK++Q+A++Y + K II WYIMTSG T +T+ FF ++ YFG Sbjct: 129 ELPSQKSLFQIQAEKILKIEQLAQQYLKSTKKPIINWYIMTSGPTRNATESFFIENNYFG 188 Query: 186 LKKENVIFFQQGMLPAMSFDG-KIILEEKNKVSMAPDGNGGLYRALAAQNIVEDMEQRGI 244 L VIFF QG LP + G KI+LE KN + +PDGNGGLY+AL I++D+ +GI Sbjct: 189 LNSHQVIFFNQGTLPCFNLQGNKILLELKNSICQSPDGNGGLYKALKDNGILDDLNSKGI 248 Query: 245 WSIHVYCVDNILVKVADPRFIGFCIQKGADCGAKVVEKTNPTEPVGVVCRVDGVYQ---V 301 IH+YCVDN LVKVADP FIGF I K D KVV K + E VG++ +D Q V Sbjct: 249 KHIHMYCVDNCLVKVADPIFIGFAIAKKFDLATKVVRKRDANESVGLIV-LDQDNQKPCV 307 Query: 302 VEYSEISLATAQKRS--SDGRLLFNAGNIANHFFTVPFLRDVVNVY---EPQLQHHVAQK 356 +EYSEIS A K+ +L A NI NH+++V FL ++ + + L H+A+K Sbjct: 308 IEYSEISQELANKKDPQDSSKLFLRAANIVNHYYSVEFLNKMIPKWISSQKYLPFHIAKK 367 Query: 357 KIPYVDTQ-GQLIKPDKPNGIKMEKFVFDIFQFAK--KFVVYEVLREDEFSPLKNADSQN 413 KIP ++ + G+ KP +PNGIK+E+F+FD+F + KF EV R DEFSPLKNAD Sbjct: 368 KIPSLNLENGEFYKPTEPNGIKLEQFIFDVFPSVELNKFGCLEVDRLDEFSPLKNADGAK 427 Query: 414 GKDNPTTARHALMSLHHCWVLNAGGHFIDENG 445 D PTT R+ + WV+ GG ID G Sbjct: 428 N-DTPTTCRNHYLERSSKWVIQNGG-VIDNQG 457 >3OC9-A nrPDB Length = 405 Score = 253 bits (645), Expect = 2e-67, Method: Compositional matrix adjust. Identities = 141/359 (39%), Positives = 221/359 (61%), Gaps = 7/359 (1%) Query: 94 GLFQISQNKVAVLLLAGGQGTRLGVAYPKGMYDVGLPSRKTLFQIQAERILKLQQVAEKY 153 GL ISQ K A++ AGGQG+RLG +PKGM+ + K++FQ+ +ER+L+LQ++A +Y Sbjct: 27 GLELISQGKTALITPAGGQGSRLGFEHPKGMFVLPFEIPKSIFQMTSERLLRLQELASEY 86 Query: 154 YGNK-CIIPWYIMTSGRTMESTKEFFTKHKYFGLKKENVIFFQQGMLPAMSFDGKIILEE 212 K +I W++MT+ T+E +F +H+YFGL E + F QGMLP + F+GKI+ E+ Sbjct: 87 SHQKNVMIHWFLMTNEETIEEINNYFKEHQYFGLSSEQIHCFPQGMLPVVDFNGKILYEK 146 Query: 213 KNKVSMAPDGNGGLYRALAAQNIVEDMEQRGIWSIHVYCVDNILVKVADPRFIGFCIQKG 272 K+K MAP+G+GGL++AL I+E M ++GI + VDNIL K DP IG+ Sbjct: 147 KDKPYMAPNGHGGLFKALKDNGILEFMNEKGIKYSVAHNVDNILCKDVDPNMIGYMDLLQ 206 Query: 273 ADCGAKVVEKTNPTEPVGVVCRVDGVYQVVEYSEISLATAQKRSSDGRLLFNAGNIANHF 332 ++ K+V+K E VGV+ + +VVEY+E++ K+ S+G ++N G+I+ + Sbjct: 207 SEICIKIVKKGFKEEKVGVLVKEQERIKVVEYTELT-DELNKQLSNGEFIYNCGHISING 265 Query: 333 FTVPFLRDVVNVYEPQLQHHVAQKKIPYVDTQGQLIKPDKPNGIKMEKFVFDIFQFAKKF 392 ++ FL E QL +H+A+KK+P+V+ QG +I P + NGIK E F FD+F A K Sbjct: 266 YSTSFLEKAA---EYQLPYHIAKKKVPFVNEQGIVIHPSENNGIKKEIFFFDVFPLATKV 322 Query: 393 VVYEVLREDEFSPLKNADSQNGKDNPTTARHALMSLHHCWVLNAGGHFIDENGSRLPAI 451 ++E+ R EFS LKN+ +++ DN T + L + + L G +D++ S + I Sbjct: 323 SIFEIQRFIEFSALKNSLNESF-DNVNTVKRDWYRL-NIYYLKKAGAIVDDSKSPICEI 379 >4BQH-A nrPDB Length = 549 Score = 252 bits (643), Expect = 3e-67, Method: Compositional matrix adjust. Identities = 175/554 (31%), Positives = 280/554 (50%), Gaps = 82/554 (14%) Query: 10 LSKAGQEHLLRFWNELEEAQQVELYA----ELQAMNFEELNFFFQKAIEGFNQSSHQKNV 65 L+ A Q+H+L EA++ L A EL ++F N ++++E S + Sbjct: 15 LTGANQDHILTALEHGSEAERASLTAQITNELAGVDFRHFNDVLRESLE----ISKNCST 70 Query: 66 DARMEPVPREV---LGSATRDQDQ---LQAWESEGLFQISQNKVAVLLLAGGQGTRLGVA 119 + EP ++ + S R + Q ++ E+ G I + ++A L+LAGG GTRLG Sbjct: 71 ASLAEPPAKDSFFDISSVDRRRGQAKRIKNLEAVGYKAIQKGQIAFLILAGGSGTRLGFD 130 Query: 120 YPKGMYDV-GLPSRKTLFQIQAERILKLQQVAEKYYGN--KCIIPWYIMTSGRTMESTKE 176 PKG + GL RK+LF + E+I + Q++AE G+ K + +MTSG+ T+ Sbjct: 131 KPKGFFTCDGLQQRKSLFMMHCEKIRRRQEIAESISGSGRKARVQLLVMTSGQNDAETQR 190 Query: 177 FFTKHKYFGLKKENVIFFQQGMLPAMSFD-GKIILEEKNKVSMAPDGNGGLYRALAA--- 232 FF ++ YFGL++E V FF Q +P + G+II+E + ++ AP GNG ++ ALAA Sbjct: 191 FFEENSYFGLEREQVHFFAQSSVPCYDENTGRIIMENRGRICAAPGGNGAVFAALAAPRA 250 Query: 233 -----------QNIVEDMEQRGIWSIHVYCVDNILVKVADPRFIGFCIQKGADCGAKVVE 281 +++++ + + GI + + +DN+L VADP FIG+ I++ A K Sbjct: 251 TKDKDGTLQVKESLLQHLRKLGIAYVQIGNIDNLLANVADPVFIGYAIEEEAHVVVKTCP 310 Query: 282 KTNPTEPVGVVCRVDGVYQVVEYSEISLATAQKRSSDGRLLFNAGNIANHFFTVPFLRDV 341 K P E VGV R G + VVEY+EI + + G L FN NI+++ ++ F+ Sbjct: 311 KRGPDERVGVFVRASGKWGVVEYTEIGDRAKEIDDATGELKFNCANISSNLCSLHFMSLA 370 Query: 342 VNVYEPQLQHHVAQKKIPYVDTQGQLIKPDKPNGIKMEKFVFDIFQFAKK---------- 391 + Q+H A+KKIP + +G ++ GIK+E F+FD+F+F + Sbjct: 371 AERMKSFTQYHAARKKIPTI--KGPVM------GIKLEAFLFDLFRFVDECDHPPKDSGA 422 Query: 392 FVVYEVLREDEFSPLKNADSQNGKDNPTTARHALMSLHHCWVLNAGGHFIDENGSRLPAI 451 F + +V R+DEF P+KNAD D P A L+S H W++ A+ Sbjct: 423 FRIMQVDRDDEFGPVKNADGA-ASDTPADAVRLLLSQHTRWLIT--------------AL 467 Query: 452 PRSATNGKSETITADVN-HNLKDA----NDVPIQCEISPLISYAGEGLESYVADKEFHAP 506 +A + + E+I V+ K+A I+ EISPL+S GEGL H P Sbjct: 468 ETAAMSDEQESIRGGVDVTEAKEAVAVMRSCSIKAEISPLVSVGGEGLRQ-------HLP 520 Query: 507 LIIDENGVHELVKN 520 +I H+L++N Sbjct: 521 RVI-----HQLLRN 529 >3R2W-A nrPDB Length = 528 Score = 54.7 bits (130), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 81/345 (23%), Positives = 146/345 (42%), Gaps = 45/345 (13%) Query: 17 HLLRFWNELEEAQQVELYAELQAMNFEELNFFFQKAIEGF--NQSSHQ-----KNVDA-- 67 H+ RF +L +A + ++ Q + +EL +K +E SSH+ K++D Sbjct: 20 HMSRFVQDLSKAMSQDGASQFQEVIRQELELSVKKELEKILTTASSHEFEHTKKDLDGFR 79 Query: 68 ------RMEPVPREVLGSATRD-QDQLQAWE---SEGL-FQISQ--NKVAVLLLAGGQGT 114 E P G R +D +Q +E + GL IS NK+ V+ L GG GT Sbjct: 80 KLFHRFLQEKGPSVDWGKIQRPPEDSIQPYEKIKARGLPDNISSVLNKLVVVKLNGGLGT 139 Query: 115 RLGVAYPKGMYDVGLPSRKTLFQIQAERILKLQQVAEKYYGNKCIIPWYIMTSGRTMEST 174 +G PK + +G+ + T + ++I L K Y +P +M S T E T Sbjct: 140 SMGCKGPKSL--IGVRNENTFLDLTVQQIEHLN----KTYNTD--VPLVLMNSFNTDEDT 191 Query: 175 KEFFTKHKYFGLKKENVIFFQQGMLPAMSFDGKIILEE------KNKVSMAPDGNGGLYR 228 K+ K+ + +K + F Q P ++ + + + + +N + P G+G +Y Sbjct: 192 KKILQKYNHCRVK---IYTFNQSRYPRINKESLLPVAKDVSYSGENTEAWYPPGHGDIYA 248 Query: 229 ALAAQNIVEDMEQRGIWSIHVYCVDNILVKVADPRFIGFCIQ--KGADCG--AKVVEKTN 284 + +++ G I V +DN+ V D + + G C +V KT Sbjct: 249 SFYNSGLLDTFIGEGKEYIFVSNIDNLGATV-DLYILNHLMNPPNGKRCEFVMEVTNKTR 307 Query: 285 PTEPVGVVCRVDGVYQVVEYSEISLATAQKRSSDGRL-LFNAGNI 328 G + + +G ++VE +++ A + S + +FN N+ Sbjct: 308 ADVKGGTLTQYEGKLRLVEIAQVPKAHVDEFKSVSKFKIFNTNNL 352 >2I5K-A nrPDB Length = 488 Score = 46.2 bits (108), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 63/290 (21%), Positives = 126/290 (43%), Gaps = 27/290 (9%) Query: 23 NELEEAQQVELYAELQAMNFEELNFFFQKAIEGFNQSSHQKNV--DARMEPVPREVLGSA 80 N+L ++ +++ A + N EL+ FF + S + + D P P EV+ Sbjct: 21 NKLADSSKLDDAARAKFEN--ELDSFFTLFRRYLVEKSSRTTLEWDKIKSPNPDEVV--- 75 Query: 81 TRDQDQLQAWESEGLFQISQNKVAVLLLAGGQGTRLGVAYPKGMYDVGLPSRKTLFQIQA 140 + ++ + + E + +S K+AVL L GG GT +G PK + +V T + Sbjct: 76 ---KYEIISQQPENVSNLS--KLAVLKLNGGLGTSMGCVGPKSVIEVR--EGNTFLDLSV 128 Query: 141 ERILKLQQVAEKYYGNKCIIPWYIMTSGRTMESTKEFFTKHKYFGLKKENVIFFQQGMLP 200 +I L + +Y + +P +M S T + T+ K + + + F Q P Sbjct: 129 RQIEYLNR---QYDSD---VPLLLMNSFNTDKDTEHLIKK---YSANRIRIRSFNQSRFP 179 Query: 201 AMSFDGKIILEEKNKVSMA---PDGNGGLYRALAAQNIVEDMEQRGIWSIHVYCVDNILV 257 + D + + + + P G+G L+ +L ++ + +G + V DN+ Sbjct: 180 RVYKDSLLPVPTEYDSPLDAWYPPGHGDLFESLHVSGELDALIAQGREILFVSNGDNLGA 239 Query: 258 KVADPRFIGFCIQKGADCGAKVVEKTNPTEPVGVVCRVDGVYQVVEYSEI 307 V D + + I+ GA+ ++ +KT G + DG +++E +++ Sbjct: 240 TV-DLKILNHMIETGAEYIMELTDKTRADVKGGTLISYDGQVRLLEVAQV 288 >3GUE-A nrPDB Length = 484 Score = 44.7 bits (104), Expect = 9e-05, Method: Compositional matrix adjust. Identities = 45/187 (24%), Positives = 77/187 (41%), Gaps = 11/187 (5%) Query: 87 LQAWESEGLFQISQNKVAVLLLAGGQGTRLGVAYPKGMYDVGLPSRKTLFQIQAERILKL 146 LQ E++G + VL L GG GT +G+ PK + V + +T A ++ Sbjct: 61 LQGIETKGENTALLRQAVVLKLNGGLGTGMGLNGPKSLLQV--KNGQTFLDFTALQLEHF 118 Query: 147 QQVAEKYYGNKCIIPWYIMTSGRTMESTKEFFTKHKYFGLKKENVIFFQQGMLPAMSFDG 206 +QV C +P+ +M S T TK F K+ ++ I Q +P + D Sbjct: 119 RQV------RNCNVPFMLMNSFSTSGETKNFLRKYPTLYEVFDSDIELMQNRVPKIRQDN 172 Query: 207 --KIILEEKNKVSMAPDGNGGLYRALAAQNIVEDMEQRGIWSIHVYCVDNILVKVADPRF 264 + E P G+G +Y L + ++ + +G + + DN L D R Sbjct: 173 FFPVTYEADPTCEWVPPGHGDVYTVLYSSGKLDYLLGKGYRYMFISNGDN-LGATLDVRL 231 Query: 265 IGFCIQK 271 + + +K Sbjct: 232 LDYMHEK 238 >4M2B-A nrPDB Length = 505 Score = 39.3 bits (90), Expect = 0.004, Method: Compositional matrix adjust. Identities = 47/194 (24%), Positives = 85/194 (43%), Gaps = 14/194 (7%) Query: 105 VLLLAGGQGTRLGVAYPKGMYDVGLPSRKTLFQIQAERILKLQQVAEKYYGNKCIIPWYI 164 VL L GG GT +G+ K + +V KT A ++ L+Q ++ + + + Sbjct: 78 VLKLNGGLGTGMGLCDAKTLLEV--KDGKTFLDFTALQVQYLRQHCSEH------LRFML 129 Query: 165 MTSGRTMESTKEFFTKHKYFGLKK--ENVIFFQQGMLPAMSFDG--KIILEEKNKVSMAP 220 M S T STK F K +Y L + ++ + Q +P + D E AP Sbjct: 130 MDSFNTSASTKSFL-KARYPWLYQVFDSEVELMQNQVPKILQDTLEPAAWAENPAYEWAP 188 Query: 221 DGNGGLYRALAAQNIVEDMEQRGIWSIHVYCVDNILVKVADPRFIGFCIQKGADCGAKVV 280 G+G +Y AL ++++ ++G + V DN+ + D R + + ++ D +V Sbjct: 189 PGHGDIYTALYGSGKLQELVEQGYRYMFVSNGDNLGATI-DKRVLAYMEKEKIDFLMEVC 247 Query: 281 EKTNPTEPVGVVCR 294 +T + G + R Sbjct: 248 RRTESDKKGGHLAR 261 >3OH0-A nrPDB Length = 641 Score = 35.4 bits (80), Expect = 0.065, Method: Compositional matrix adjust. Identities = 72/322 (22%), Positives = 122/322 (37%), Gaps = 44/322 (13%) Query: 2 NINDLKLTLSKAG--QEHLLRFWNELEEA---QQVELYAEL---QAMNFEELNFFFQKAI 53 N+ L+ L G Q HL W E + +Q+ L +L M + + + Sbjct: 8 NLQALREELCTPGLDQGHLFEGWPETVDECNERQIALLTDLYMFSNMYPGGVAQYIRNGH 67 Query: 54 EGFNQSSHQKNVDA-RMEPVPREVLGSATRDQDQLQAWESEGLFQISQNKVAVLLLAGGQ 112 E + S + + A M P+ E S R + A E+ G + K +L+AGG Sbjct: 68 ELLARESEEVDFAALEMPPLIFEA-PSLHRRTAERTALENAGTAMLC--KTVFVLVAGGL 124 Query: 113 GTRLGVAYPKGMYDVGLPSRKTLFQIQAERILKLQQVAEKYYGNKCIIPWYIMTSGRTME 172 G RLG + K V LP L+ A++ G + +P+ IMTS T + Sbjct: 125 GERLGYSSIK----VSLPVETATNTTYLAYYLRW---AQRVGGKE--VPFVIMTSDDTHD 175 Query: 173 STKEFFTKHKYFGLKKENVIFFQQGMLPAMSFDGK-IILEEKNKVSMAPDGNGGLYRAL- 230 T + + + + N+ +QG + + + L+E K+ P G+G ++ + Sbjct: 176 RTLQLLRELQL---EVPNLHVLKQGQVFCFADSAAHLALDETGKLLRKPHGHGDVHSLIY 232 Query: 231 -----------------AAQNIVEDMEQRGIWSIHVYCVDNILVKVADPRFIGFCIQKGA 273 AQ +V D G SI N + P + + Sbjct: 233 NATVKRDVVPDSGDGTATAQPLVNDWLAAGYESIVFIQDTNAGATITIPISLALSAEHSL 292 Query: 274 DCGAKVVEKTNPTEPVGVVCRV 295 D + + P EP+G++CR Sbjct: 293 DMNFTCIPRV-PKEPIGLLCRT 313 >4NAK-A nrPDB Length = 228 Score = 31.6 bits (70), Expect = 0.98, Method: Compositional matrix adjust. Identities = 12/23 (52%), Positives = 18/23 (78%) Query: 100 QNKVAVLLLAGGQGTRLGVAYPK 122 + V+V+LLAGGQG R+ ++ PK Sbjct: 2 EKSVSVILLAGGQGKRMKMSMPK 24 >6DTT-A nrPDB Length = 383 Score = 30.0 bits (66), Expect = 2.5, Method: Compositional matrix adjust. Identities = 21/72 (29%), Positives = 35/72 (48%), Gaps = 4/72 (5%) Query: 347 PQLQHHVAQKKIPYVDTQGQLIKPDKPNGIKMEKFVFDIFQFAKKFVVYEVLREDEFSPL 406 P+L+ V K P+V QG +I PN + +F+ + A+K +Y++ D P Sbjct: 249 PELEPGVPAK--PFVGVQGFMINAKSPNKVIAMEFLTNF--IARKETMYKIYLADPRLPA 304 Query: 407 KNADSQNGKDNP 418 + + KDNP Sbjct: 305 RKDVLELVKDNP 316 >4V7H-AC nrPDB Length = 188 Score = 30.0 bits (66), Expect = 2.7, Method: Compositional matrix adjust. Identities = 18/48 (37%), Positives = 26/48 (54%), Gaps = 8/48 (16%) Query: 42 FEELNFFFQKAI--EGFNQSSHQKNVDARMEPVPREVLGSATRDQDQL 87 + ELN FF + + EG++ V+ R+ P EV+ ATR QD L Sbjct: 13 YAELNEFFTRELAEEGYS------GVEVRVTPTKTEVIIRATRTQDVL 54 >4BSZ-A nrPDB Length = 244 Score = 29.6 bits (65), Expect = 3.4, Method: Compositional matrix adjust. Identities = 19/48 (39%), Positives = 26/48 (54%), Gaps = 8/48 (16%) Query: 42 FEELNFFFQK--AIEGFNQSSHQKNVDARMEPVPREVLGSATRDQDQL 87 + ELN FF + A EG++ V+ R+ P EV+ ATR QD L Sbjct: 22 YAELNEFFTRELAEEGYS------GVEVRVTPTKTEVIIRATRTQDVL 63 >4XAX-A nrPDB Length = 184 Score = 28.9 bits (63), Expect = 5.7, Method: Compositional matrix adjust. Identities = 16/43 (37%), Positives = 24/43 (55%), Gaps = 2/43 (4%) Query: 181 HKYFGLKKENVIFFQQGMLPAMSFDGKIILEEKNKVSMAPDGN 223 HK GL KE+ +F G LP M+ DG I+ ++V ++ G Sbjct: 86 HKDTGLIKEDEVFL--GHLPLMTEDGSFIINGADRVIVSQGGR 126 >3RR5-A nrPDB Length = 570 Score = 28.5 bits (62), Expect = 6.5, Method: Compositional matrix adjust. Identities = 14/56 (25%), Positives = 30/56 (53%) Query: 16 EHLLRFWNELEEAQQVELYAELQAMNFEELNFFFQKAIEGFNQSSHQKNVDARMEP 71 E R +EE++++++ +L EE F+++A+E ++ K +D+ EP Sbjct: 367 ERRKRLEESVEESEKIKIAEQLVTKKVEEAEAFYKRALELGHEGLMAKRLDSVYEP 422 >3K92-A nrPDB Length = 424 Score = 28.1 bits (61), Expect = 8.9, Method: Compositional matrix adjust. Identities = 17/43 (39%), Positives = 21/43 (48%) Query: 185 GLKKENVIFFQQGMLPAMSFDGKIILEEKNKVSMAPDGNGGLY 227 G+K +N QG A SF K + + KV D NGGLY Sbjct: 216 GIKLQNARIIIQGFGNAGSFLAKFMHDAGAKVIGISDANGGLY 258 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 1VM8-A nrPDB 793 0.0 1JV1-A nrPDB 776 0.0 4BMA-A nrPDB 564 e-161 4BQH-A nrPDB 525 e-149 2YQJ-A nrPDB 502 e-142 3OC9-A nrPDB 440 e-124 3R2W-A nrPDB 297 1e-80 2I5K-A nrPDB 291 4e-79 3GUE-A nrPDB 234 6e-62 Sequences not found previously or not previously below threshold: 5WEG-A nrPDB 202 3e-52 2Q4J-A nrPDB 197 9e-51 4M2B-A nrPDB 173 2e-43 3OH0-A nrPDB 77 2e-14 6IGX-B nrPDB 33 0.28 4CVH-A nrPDB 33 0.30 5V7X-A nrPDB 32 0.77 4E77-A nrPDB 31 0.97 2PX7-A nrPDB 31 1.3 4MYB-A nrPDB 31 1.5 4G3P-A nrPDB 30 2.5 2QKX-A nrPDB 30 2.5 2MPH-A nrPDB 29 4.6 4NAK-A nrPDB 29 4.8 >1VM8-A nrPDB Length = 534 Score = 793 bits (2048), Expect = 0.0, Method: Composition-based stats. Identities = 487/522 (93%), Positives = 506/522 (96%) Query: 1 MNINDLKLTLSKAGQEHLLRFWNELEEAQQVELYAELQAMNFEELNFFFQKAIEGFNQSS 60 MN+NDLK LS+AGQEHLL+FWNEL EAQQ+ELY ELQAMNFEELN FF+KAI F++SS Sbjct: 13 MNVNDLKQRLSQAGQEHLLQFWNELSEAQQMELYMELQAMNFEELNSFFRKAIGEFDRSS 72 Query: 61 HQKNVDARMEPVPREVLGSATRDQDQLQAWESEGLFQISQNKVAVLLLAGGQGTRLGVAY 120 HQ+ VDARMEPVPR+VLGSATRDQ+QLQAWESEGL QISQNKVAVLLLAGGQGTRLGV+Y Sbjct: 73 HQEKVDARMEPVPRQVLGSATRDQEQLQAWESEGLSQISQNKVAVLLLAGGQGTRLGVSY 132 Query: 121 PKGMYDVGLPSRKTLFQIQAERILKLQQVAEKYYGNKCIIPWYIMTSGRTMESTKEFFTK 180 PKGMYDVGLPS KTLFQIQAERILKLQQ+AEK++GNKC IPWYIMTSGRTMESTKEFFTK Sbjct: 133 PKGMYDVGLPSHKTLFQIQAERILKLQQLAEKHHGNKCTIPWYIMTSGRTMESTKEFFTK 192 Query: 181 HKYFGLKKENVIFFQQGMLPAMSFDGKIILEEKNKVSMAPDGNGGLYRALAAQNIVEDME 240 HK+FGLKKENV+FFQQGMLPAMSFDGKIILEEKNKVSMAPDGNGGLYRALAAQNIVEDME Sbjct: 193 HKFFGLKKENVVFFQQGMLPAMSFDGKIILEEKNKVSMAPDGNGGLYRALAAQNIVEDME 252 Query: 241 QRGIWSIHVYCVDNILVKVADPRFIGFCIQKGADCGAKVVEKTNPTEPVGVVCRVDGVYQ 300 QRGI SIHVYCVDNILVKVADPRFIGFCIQKGADCGAKVVEKTNPTEPVGVVCRVDGVYQ Sbjct: 253 QRGICSIHVYCVDNILVKVADPRFIGFCIQKGADCGAKVVEKTNPTEPVGVVCRVDGVYQ 312 Query: 301 VVEYSEISLATAQKRSSDGRLLFNAGNIANHFFTVPFLRDVVNVYEPQLQHHVAQKKIPY 360 VVEYSEISLATAQ+RSSDGRLLFNAGNIANHFFTVPFL+DVVNVYEPQLQHHVAQKKIPY Sbjct: 313 VVEYSEISLATAQRRSSDGRLLFNAGNIANHFFTVPFLKDVVNVYEPQLQHHVAQKKIPY 372 Query: 361 VDTQGQLIKPDKPNGIKMEKFVFDIFQFAKKFVVYEVLREDEFSPLKNADSQNGKDNPTT 420 VD+QG IKPDKPNGIKMEKFVFDIFQFAKKFVVYEVLREDEFSPLKNADSQNGKDNPTT Sbjct: 373 VDSQGYFIKPDKPNGIKMEKFVFDIFQFAKKFVVYEVLREDEFSPLKNADSQNGKDNPTT 432 Query: 421 ARHALMSLHHCWVLNAGGHFIDENGSRLPAIPRSATNGKSETITADVNHNLKDANDVPIQ 480 ARHALMSLHHCWVLNAGGHFIDENGSRLPAIPRSATNGKSE ITADVNHNLKDANDVPIQ Sbjct: 433 ARHALMSLHHCWVLNAGGHFIDENGSRLPAIPRSATNGKSEAITADVNHNLKDANDVPIQ 492 Query: 481 CEISPLISYAGEGLESYVADKEFHAPLIIDENGVHELVKNGI 522 CEISPLISYAGEGLE YVADKEFHAPLIIDENGVHELVKNGI Sbjct: 493 CEISPLISYAGEGLEGYVADKEFHAPLIIDENGVHELVKNGI 534 >1JV1-A nrPDB Length = 505 Score = 776 bits (2004), Expect = 0.0, Method: Composition-based stats. Identities = 505/522 (96%), Positives = 505/522 (96%), Gaps = 17/522 (3%) Query: 1 MNINDLKLTLSKAGQEHLLRFWNELEEAQQVELYAELQAMNFEELNFFFQKAIEGFNQSS 60 MNINDLKLTLSKAGQEHLLRFWNELEEAQQVELYAELQAMNFEELNFFFQKAIEGFNQSS Sbjct: 1 MNINDLKLTLSKAGQEHLLRFWNELEEAQQVELYAELQAMNFEELNFFFQKAIEGFNQSS 60 Query: 61 HQKNVDARMEPVPREVLGSATRDQDQLQAWESEGLFQISQNKVAVLLLAGGQGTRLGVAY 120 HQKNVDARMEPVPREVLGSATRDQDQLQAWESEGLFQISQNKVAVLLLAGGQGTRLGVAY Sbjct: 61 HQKNVDARMEPVPREVLGSATRDQDQLQAWESEGLFQISQNKVAVLLLAGGQGTRLGVAY 120 Query: 121 PKGMYDVGLPSRKTLFQIQAERILKLQQVAEKYYGNKCIIPWYIMTSGRTMESTKEFFTK 180 PKGMYDVGLPSRKTLFQIQAERILKLQQVAEKYYGNKCIIPWYIMTSGRTMESTKEFFTK Sbjct: 121 PKGMYDVGLPSRKTLFQIQAERILKLQQVAEKYYGNKCIIPWYIMTSGRTMESTKEFFTK 180 Query: 181 HKYFGLKKENVIFFQQGMLPAMSFDGKIILEEKNKVSMAPDGNGGLYRALAAQNIVEDME 240 HKYFGLKKENVIFFQQGMLPAMSFDGKIILEEKNKVSMAPDGNGGLYRALAAQNIVEDME Sbjct: 181 HKYFGLKKENVIFFQQGMLPAMSFDGKIILEEKNKVSMAPDGNGGLYRALAAQNIVEDME 240 Query: 241 QRGIWSIHVYCVDNILVKVADPRFIGFCIQKGADCGAKVVEKTNPTEPVGVVCRVDGVYQ 300 QRGIWSIHVYCVDNILVKVADPRFIGFCIQKGADCGAKVVEKTNPTEPVGVVCRVDGVYQ Sbjct: 241 QRGIWSIHVYCVDNILVKVADPRFIGFCIQKGADCGAKVVEKTNPTEPVGVVCRVDGVYQ 300 Query: 301 VVEYSEISLATAQKRSSDGRLLFNAGNIANHFFTVPFLRDVVNVYEPQLQHHVAQKKIPY 360 VVEYSEISLATAQKRSSDGRLLFNAGNIANHFFTVPFLRDVVNVYEPQLQHHVAQKKIPY Sbjct: 301 VVEYSEISLATAQKRSSDGRLLFNAGNIANHFFTVPFLRDVVNVYEPQLQHHVAQKKIPY 360 Query: 361 VDTQGQLIKPDKPNGIKMEKFVFDIFQFAKKFVVYEVLREDEFSPLKNADSQNGKDNPTT 420 VDTQGQLIKPDKPNGIKMEKFVFDIFQFAKKFVVYEVLREDEFSPLKNADSQNGKDNPTT Sbjct: 361 VDTQGQLIKPDKPNGIKMEKFVFDIFQFAKKFVVYEVLREDEFSPLKNADSQNGKDNPTT 420 Query: 421 ARHALMSLHHCWVLNAGGHFIDENGSRLPAIPRSATNGKSETITADVNHNLKDANDVPIQ 480 ARHALMSLHHCWVLNAGGHFIDENGSRLPAIPR LKDANDVPIQ Sbjct: 421 ARHALMSLHHCWVLNAGGHFIDENGSRLPAIPR-----------------LKDANDVPIQ 463 Query: 481 CEISPLISYAGEGLESYVADKEFHAPLIIDENGVHELVKNGI 522 CEISPLISYAGEGLESYVADKEFHAPLIIDENGVHELVKNGI Sbjct: 464 CEISPLISYAGEGLESYVADKEFHAPLIIDENGVHELVKNGI 505 >4BMA-A nrPDB Length = 509 Score = 564 bits (1454), Expect = e-161, Method: Composition-based stats. Identities = 229/512 (44%), Positives = 312/512 (60%), Gaps = 45/512 (8%) Query: 6 LKLTLSKAGQEHLLRFWNELEEAQQVELYAELQAMNFEELNFFFQKAIEGFNQSSHQKNV 65 L+ + AGQ H+ F +EL+ ++ +L+ +L + + +N KA+ + Sbjct: 35 LRKKYTDAGQGHVFAFVDELQTGERSQLFHQLSSFDPVRINELADKAL----NPPKADDG 90 Query: 66 DARMEPVPREVLGSATR-DQDQLQAWESEGLFQISQNKVAVLLLAGGQGTRLGVAYPKGM 124 A +EP+P S D L+ W EGL ++ NKVAV+L+AGGQGTRLG + PKG Sbjct: 91 PASLEPLPDIATASILDSDPKDLEQWYEEGLKLVAGNKVAVVLMAGGQGTRLGSSAPKGC 150 Query: 125 YDVGLPSRKTLFQIQAERILKLQQVAEKYYGNKCIIPWYIMTSGRTMESTKEFFTKHKYF 184 +D+GLPS K+LFQIQAERI KLQ +A++ G + +IPWY+MTSG T + T+EFF +HKYF Sbjct: 151 FDIGLPSHKSLFQIQAERIAKLQLLAQRISGKEAVIPWYVMTSGPTRKPTEEFFEQHKYF 210 Query: 185 GLKKENVIFFQQGMLPAMSFDGKIILEEKNKVSMAPDGNGGLYRALAAQNIVEDMEQRGI 244 GL K +VI F+QG+LP +S +GKI++E K KV++APDGNGG+Y+AL + EDM +RGI Sbjct: 211 GLNKSDVIIFEQGVLPCISNEGKILMESKFKVAVAPDGNGGIYQALLTSGVREDMRKRGI 270 Query: 245 WSIHVYCVDNILVKVADPRFIGFCIQKGADCGAKVVEKTNPTEPVGVVCRVDGVYQVVEY 304 IH YCVDN LVKVADP FIGF K D KVV K N TE VG++ + +G VVEY Sbjct: 271 EHIHTYCVDNCLVKVADPVFIGFAASKQVDIATKVVRKRNATESVGLILQKNGKPDVVEY 330 Query: 305 SEISLATAQKRSSD--GRLLFNAGNIANHFFTVPFLRDVVNVYEPQLQHHVAQKKIPYV- 361 SEI TA+ + L F A NI NH+++ F + ++ +L HHVA+KKIP + Sbjct: 331 SEIDKETAEAKDPKQPDVLKFRAANIVNHYYSFKFFE-SIELWAHKLPHHVARKKIPCIK 389 Query: 362 DTQGQLIKPDKPNGIKMEKFVFDIFQFA--KKFVVYEVLREDEFSPLKNADSQNGKDNPT 419 + G+ KP+KPNGIK+E+FVFD+F +KF EV REDEFSPLKNA G+D+P Sbjct: 390 EGTGEFFKPEKPNGIKLEQFVFDVFPMTPLEKFACIEVRREDEFSPLKNARG-TGEDDPD 448 Query: 420 TARHALMSLHHCWVLNAGGHFIDENGSRLPAIPRSATNGKSETITADVNHNLKDANDVPI 479 T++ +MS W+ AGG I E DV + Sbjct: 449 TSKRDIMSQGQRWIEKAGGIVITE---------------------GDV-----------V 476 Query: 480 QCEISPLISYAGEGLESYVADKEFHAPLIIDE 511 E+SPLISY GEGLE ++ +E AP I++ Sbjct: 477 GVEVSPLISYGGEGLE-FLKGREIKAPAFIEK 507 >4BQH-A nrPDB Length = 549 Score = 525 bits (1351), Expect = e-149, Method: Composition-based stats. Identities = 174/556 (31%), Positives = 279/556 (50%), Gaps = 82/556 (14%) Query: 8 LTLSKAGQEHLLRFWNELEEAQQVELYAE----LQAMNFEELNFFFQKAIEGFNQSSHQK 63 L+ A Q+H+L EA++ L A+ L ++F N ++++E S Sbjct: 13 QRLTGANQDHILTALEHGSEAERASLTAQITNELAGVDFRHFNDVLRESLE----ISKNC 68 Query: 64 NVDARMEPVPRE---VLGSATRDQDQ---LQAWESEGLFQISQNKVAVLLLAGGQGTRLG 117 + + EP ++ + S R + Q ++ E+ G I + ++A L+LAGG GTRLG Sbjct: 69 STASLAEPPAKDSFFDISSVDRRRGQAKRIKNLEAVGYKAIQKGQIAFLILAGGSGTRLG 128 Query: 118 VAYPKGMYDV-GLPSRKTLFQIQAERILKLQQVAEKYYG--NKCIIPWYIMTSGRTMEST 174 PKG + GL RK+LF + E+I + Q++AE G K + +MTSG+ T Sbjct: 129 FDKPKGFFTCDGLQQRKSLFMMHCEKIRRRQEIAESISGSGRKARVQLLVMTSGQNDAET 188 Query: 175 KEFFTKHKYFGLKKENVIFFQQGMLPAMSFD-GKIILEEKNKVSMAPDGNGGLYRALAA- 232 + FF ++ YFGL++E V FF Q +P + G+II+E + ++ AP GNG ++ ALAA Sbjct: 189 QRFFEENSYFGLEREQVHFFAQSSVPCYDENTGRIIMENRGRICAAPGGNGAVFAALAAP 248 Query: 233 -------------QNIVEDMEQRGIWSIHVYCVDNILVKVADPRFIGFCIQKGADCGAKV 279 +++++ + + GI + + +DN+L VADP FIG+ I++ A K Sbjct: 249 RATKDKDGTLQVKESLLQHLRKLGIAYVQIGNIDNLLANVADPVFIGYAIEEEAHVVVKT 308 Query: 280 VEKTNPTEPVGVVCRVDGVYQVVEYSEISLATAQKRSSDGRLLFNAGNIANHFFTVPFLR 339 K P E VGV R G + VVEY+EI + + G L FN NI+++ ++ F+ Sbjct: 309 CPKRGPDERVGVFVRASGKWGVVEYTEIGDRAKEIDDATGELKFNCANISSNLCSLHFMS 368 Query: 340 DVVNVYEPQLQHHVAQKKIPYVDTQGQLIKPDKPNGIKMEKFVFDIFQFAKK-------- 391 + Q+H A+KKIP + +G ++ GIK+E F+FD+F+F + Sbjct: 369 LAAERMKSFTQYHAARKKIPTI--KGPVM------GIKLEAFLFDLFRFVDECDHPPKDS 420 Query: 392 --FVVYEVLREDEFSPLKNADSQNGKDNPTTARHALMSLHHCWVLNAGGHFIDENGSRLP 449 F + +V R+DEF P+KNAD D P A L+S H W++ Sbjct: 421 GAFRIMQVDRDDEFGPVKNADGA-ASDTPADAVRLLLSQHTRWLIT-------------- 465 Query: 450 AIPRSATNGKSETITADVN-HNLKDA----NDVPIQCEISPLISYAGEGLESYVADKEFH 504 A+ +A + + E+I V+ K+A I+ EISPL+S GEGL H Sbjct: 466 ALETAAMSDEQESIRGGVDVTEAKEAVAVMRSCSIKAEISPLVSVGGEGLRQ-------H 518 Query: 505 APLIIDENGVHELVKN 520 P +I H+L++N Sbjct: 519 LPRVI-----HQLLRN 529 >2YQJ-A nrPDB Length = 486 Score = 502 bits (1292), Expect = e-142, Method: Composition-based stats. Identities = 210/515 (40%), Positives = 283/515 (54%), Gaps = 54/515 (10%) Query: 9 TLSKAGQEHLLRFWNELEEAQQVELYAELQAMNFEELNFFFQKAIEGFNQSSHQKNVDAR 68 + +A Q+ L ++++ L QQ E +L + EE +E Q S + Sbjct: 12 SFKQANQDQLFQYYDSLTIDQQQEFIDQLSTI--EEPAKLI-STVEQAIQFSQTNSTSRN 68 Query: 69 MEPVPREVLGSATR-DQDQLQAWESEGLFQISQNKVAVLLLAGGQGTRLGVAYPKGMYDV 127 +P E S +D LQ W GL I +VAVLL+AGGQGTRLG + PKG +++ Sbjct: 69 FTQLPNEQTASTLDLSKDILQNWTELGLKAIGNGEVAVLLMAGGQGTRLGSSAPKGCFNI 128 Query: 128 GLPSRKTLFQIQAERILKLQQVAEKY--YGNKCIIPWYIMTSGRTMESTKEFFTKHKYFG 185 LPS+K+LFQIQAE+ILK++Q+A++Y K II WYIMTSG T +T+ FF ++ YFG Sbjct: 129 ELPSQKSLFQIQAEKILKIEQLAQQYLKSTKKPIINWYIMTSGPTRNATESFFIENNYFG 188 Query: 186 LKKENVIFFQQGMLPAMSFDG-KIILEEKNKVSMAPDGNGGLYRALAAQNIVEDMEQRGI 244 L VIFF QG LP + G KI+LE KN + +PDGNGGLY+AL I++D+ +GI Sbjct: 189 LNSHQVIFFNQGTLPCFNLQGNKILLELKNSICQSPDGNGGLYKALKDNGILDDLNSKGI 248 Query: 245 WSIHVYCVDNILVKVADPRFIGFCIQKGADCGAKVVEKTNPTEPVGVVC--RVDGVYQVV 302 IH+YCVDN LVKVADP FIGF I K D KVV K + E VG++ + + V+ Sbjct: 249 KHIHMYCVDNCLVKVADPIFIGFAIAKKFDLATKVVRKRDANESVGLIVLDQDNQKPCVI 308 Query: 303 EYSEISLATAQKRSS--DGRLLFNAGNIANHFFTVPFLRDVVNVY---EPQLQHHVAQKK 357 EYSEIS A K+ +L A NI NH+++V FL ++ + + L H+A+KK Sbjct: 309 EYSEISQELANKKDPQDSSKLFLRAANIVNHYYSVEFLNKMIPKWISSQKYLPFHIAKKK 368 Query: 358 IPYVDTQ-GQLIKPDKPNGIKMEKFVFDIFQFAK--KFVVYEVLREDEFSPLKNADSQNG 414 IP ++ + G+ KP +PNGIK+E+F+FD+F + KF EV R DEFSPLKNAD Sbjct: 369 IPSLNLENGEFYKPTEPNGIKLEQFIFDVFPSVELNKFGCLEVDRLDEFSPLKNADGAKN 428 Query: 415 KDNPTTARHALMSLHHCWVLNAGGHFIDENGSRLPAIPRSATNGKSETITADVNHNLKDA 474 D PTT R+ + WV+ GG ID G Sbjct: 429 -DTPTTCRNHYLERSSKWVIQNGG-VIDNQGL---------------------------- 458 Query: 475 NDVPIQCEISPLISYAGEGLESYVADKEFHAPLII 509 E+ SY GEGLE +V K F II Sbjct: 459 ------VEVDSKTSYGGEGLE-FVNGKHFKNGDII 486 >3OC9-A nrPDB Length = 405 Score = 440 bits (1131), Expect = e-124, Method: Composition-based stats. Identities = 143/388 (36%), Positives = 227/388 (58%), Gaps = 10/388 (2%) Query: 65 VDARMEPVPREVLGSATRDQDQLQAWESEGLFQISQNKVAVLLLAGGQGTRLGVAYPKGM 124 M P ++ + + GL ISQ K A++ AGGQG+RLG +PKGM Sbjct: 1 GPGSMTYQPVDITTNTIP---VTKEHYYRGLELISQGKTALITPAGGQGSRLGFEHPKGM 57 Query: 125 YDVGLPSRKTLFQIQAERILKLQQVAEKYYGNK-CIIPWYIMTSGRTMESTKEFFTKHKY 183 + + K++FQ+ +ER+L+LQ++A +Y K +I W++MT+ T+E +F +H+Y Sbjct: 58 FVLPFEIPKSIFQMTSERLLRLQELASEYSHQKNVMIHWFLMTNEETIEEINNYFKEHQY 117 Query: 184 FGLKKENVIFFQQGMLPAMSFDGKIILEEKNKVSMAPDGNGGLYRALAAQNIVEDMEQRG 243 FGL E + F QGMLP + F+GKI+ E+K+K MAP+G+GGL++AL I+E M ++G Sbjct: 118 FGLSSEQIHCFPQGMLPVVDFNGKILYEKKDKPYMAPNGHGGLFKALKDNGILEFMNEKG 177 Query: 244 IWSIHVYCVDNILVKVADPRFIGFCIQKGADCGAKVVEKTNPTEPVGVVCRVDGVYQVVE 303 I + VDNIL K DP IG+ ++ K+V+K E VGV+ + +VVE Sbjct: 178 IKYSVAHNVDNILCKDVDPNMIGYMDLLQSEICIKIVKKGFKEEKVGVLVKEQERIKVVE 237 Query: 304 YSEISLATAQKRSSDGRLLFNAGNIANHFFTVPFLRDVVNVYEPQLQHHVAQKKIPYVDT 363 Y+E++ K+ S+G ++N G+I+ + ++ FL E QL +H+A+KK+P+V+ Sbjct: 238 YTELTDE-LNKQLSNGEFIYNCGHISINGYSTSFLEKAA---EYQLPYHIAKKKVPFVNE 293 Query: 364 QGQLIKPDKPNGIKMEKFVFDIFQFAKKFVVYEVLREDEFSPLKNADSQNGKDNPTTARH 423 QG +I P + NGIK E F FD+F A K ++E+ R EFS LKN+ +++ DN T + Sbjct: 294 QGIVIHPSENNGIKKEIFFFDVFPLATKVSIFEIQRFIEFSALKNSLNESF-DNVNTVKR 352 Query: 424 ALMSLHHCWVLNAGGHFIDENGSRLPAI 451 L + + L G +D++ S + I Sbjct: 353 DWYRL-NIYYLKKAGAIVDDSKSPICEI 379 >3R2W-A nrPDB Length = 528 Score = 297 bits (759), Expect = 1e-80, Method: Composition-based stats. Identities = 82/357 (22%), Positives = 150/357 (42%), Gaps = 45/357 (12%) Query: 17 HLLRFWNELEEAQQVELYAELQAMNFEELNFFFQKAIEGF--NQSSHQ-----KNVDA-- 67 H+ RF +L +A + ++ Q + +EL +K +E SSH+ K++D Sbjct: 20 HMSRFVQDLSKAMSQDGASQFQEVIRQELELSVKKELEKILTTASSHEFEHTKKDLDGFR 79 Query: 68 ------RMEPVPREVLGSATRD-QDQLQAWE---SEGL-FQISQ--NKVAVLLLAGGQGT 114 E P G R +D +Q +E + GL IS NK+ V+ L GG GT Sbjct: 80 KLFHRFLQEKGPSVDWGKIQRPPEDSIQPYEKIKARGLPDNISSVLNKLVVVKLNGGLGT 139 Query: 115 RLGVAYPKGMYDVGLPSRKTLFQIQAERILKLQQVAEKYYGNKCIIPWYIMTSGRTMEST 174 +G PK + +G+ + T + ++I L K Y +P +M S T E T Sbjct: 140 SMGCKGPKSL--IGVRNENTFLDLTVQQIEHLN----KTYNTD--VPLVLMNSFNTDEDT 191 Query: 175 KEFFTKHKYFGLKKENVIFFQQGMLPAMSFDGKIILEE------KNKVSMAPDGNGGLYR 228 K+ K+ + +K + F Q P ++ + + + + +N + P G+G +Y Sbjct: 192 KKILQKYNHCRVK---IYTFNQSRYPRINKESLLPVAKDVSYSGENTEAWYPPGHGDIYA 248 Query: 229 ALAAQNIVEDMEQRGIWSIHVYCVDNILVKVADPRFIGFCIQ----KGADCGAKVVEKTN 284 + +++ G I V +DN+ V D + + K + +V KT Sbjct: 249 SFYNSGLLDTFIGEGKEYIFVSNIDNLGATV-DLYILNHLMNPPNGKRCEFVMEVTNKTR 307 Query: 285 PTEPVGVVCRVDGVYQVVEYSEISLATAQKRSSDGRL-LFNAGNIANHFFTVPFLRD 340 G + + +G ++VE +++ A + S + +FN N+ V L++ Sbjct: 308 ADVKGGTLTQYEGKLRLVEIAQVPKAHVDEFKSVSKFKIFNTNNLWISLAAVKRLQE 364 >2I5K-A nrPDB Length = 488 Score = 291 bits (745), Expect = 4e-79, Method: Composition-based stats. Identities = 69/340 (20%), Positives = 140/340 (41%), Gaps = 28/340 (8%) Query: 17 HLLRFWNELEEAQQVELYAELQAMNFEELNFFFQKAIEGFNQSSHQKNV--DARMEPVPR 74 + N+L ++ +++ A + N EL+ FF + S + + D P P Sbjct: 15 QMRNALNKLADSSKLDDAARAKFEN--ELDSFFTLFRRYLVEKSSRTTLEWDKIKSPNPD 72 Query: 75 EVLGSATRDQDQLQAWESEGLFQISQNKVAVLLLAGGQGTRLGVAYPKGMYDVGLPSRKT 134 EV+ + ++ + + E + +S K+AVL L GG GT +G PK + +V T Sbjct: 73 EVV------KYEIISQQPENVSNLS--KLAVLKLNGGLGTSMGCVGPKSVIEV--REGNT 122 Query: 135 LFQIQAERILKLQQVAEKYYGNKCIIPWYIMTSGRTMESTKEFFTKHKYFGLKKENVIFF 194 + +I L + +Y + +P +M S T + T+ K+ + + F Sbjct: 123 FLDLSVRQIEYLNR---QYDSD---VPLLLMNSFNTDKDTEHLIKKYS---ANRIRIRSF 173 Query: 195 QQGMLPAMSFDGKIILEEKNKVS---MAPDGNGGLYRALAAQNIVEDMEQRGIWSIHVYC 251 Q P + D + + + P G+G L+ +L ++ + +G + V Sbjct: 174 NQSRFPRVYKDSLLPVPTEYDSPLDAWYPPGHGDLFESLHVSGELDALIAQGREILFVSN 233 Query: 252 VDNILVKVADPRFIGFCIQKGADCGAKVVEKTNPTEPVGVVCRVDGVYQVVEYSEISLAT 311 DN+ V D + + I+ GA+ ++ +KT G + DG +++E +++ Sbjct: 234 GDNLGATV-DLKILNHMIETGAEYIMELTDKTRADVKGGTLISYDGQVRLLEVAQVPKEH 292 Query: 312 AQKRSSDGRLL-FNAGNIANHFFTVPFLRDVVNVYEPQLQ 350 + + + FN N+ + V L + N+ + Sbjct: 293 IDEFKNIRKFTNFNTNNLWINLKAVKRLIESSNLEMEIIP 332 >3GUE-A nrPDB Length = 484 Score = 234 bits (597), Expect = 6e-62, Method: Composition-based stats. Identities = 55/267 (20%), Positives = 101/267 (37%), Gaps = 22/267 (8%) Query: 87 LQAWESEGLFQISQNKVAVLLLAGGQGTRLGVAYPKGMYDVGLPSRKTLFQIQAERILKL 146 LQ E++G + VL L GG GT +G+ PK + V + +T A ++ Sbjct: 61 LQGIETKGENTALLRQAVVLKLNGGLGTGMGLNGPKSLLQV--KNGQTFLDFTALQLEHF 118 Query: 147 QQVAEKYYGNKCIIPWYIMTSGRTMESTKEFFTKHKYFGLKKENVIFFQQGMLPAMSFDG 206 +QV C +P+ +M S T TK F K+ ++ I Q +P + D Sbjct: 119 RQV------RNCNVPFMLMNSFSTSGETKNFLRKYPTLYEVFDSDIELMQNRVPKIRQDN 172 Query: 207 --KIILEEKNKVSMAPDGNGGLYRALAAQNIVEDMEQRGIWSIHVYCVDNILVKVADPRF 264 + E P G+G +Y L + ++ + +G + + DN+ D R Sbjct: 173 FFPVTYEADPTCEWVPPGHGDVYTVLYSSGKLDYLLGKGYRYMFISNGDNLGAT-LDVRL 231 Query: 265 IGFCIQKGADCGAKVVEKTNPTEPVGVVCRVD------GVYQ----VVEYSEISLATAQK 314 + + +K +V +T + G + D G + + E ++ Sbjct: 232 LDYMHEKQLGFLMEVCRRTESDKKGGHLAYKDVIDETTGQTRRRFVLRESAQCPKEDEDS 291 Query: 315 RSSDGR-LLFNAGNIANHFFTVPFLRD 340 + + FN NI + + + D Sbjct: 292 FQNIAKHCFFNTNNIWINLMELKKMMD 318 >5WEG-A nrPDB Length = 476 Score = 202 bits (514), Expect = 3e-52, Method: Composition-based stats. Identities = 59/326 (18%), Positives = 120/326 (36%), Gaps = 24/326 (7%) Query: 24 ELEEAQQVE----LYAELQAMNFEELNFFFQKAIEGFNQSSHQKNVDARMEPVPREVLGS 79 E+ ++++ A+L ++ E F + + Q P V+ Sbjct: 8 EVSVDEKLDKLRAEVAKLDQISENEKAGFISLVSRYLSGEAEQIEWSKIQTPTDEVVVPY 67 Query: 80 ATRDQDQLQAWESEGLFQISQNKVAVLLLAGGQGTRLGVAYPKGMYDVGLPSRKTLFQIQ 139 T E + +K+ VL L GG GT +G PK + +V + T + Sbjct: 68 DTLAS----PPEDLEETKKLLDKLVVLKLNGGLGTTMGCTGPKSVIEV--RNGFTFLDLI 121 Query: 140 AERILKLQQVAEKYYGNKCIIPWYIMTSGRTMESTKEFFTKHKYFGLKKENVIFFQQGML 199 +I L + C +P +M S T + T++ K+ + F Q Sbjct: 122 VIQIESLNK------KYGCSVPLLLMNSFNTHDDTQKIVEKYSN---SNIEIHTFNQSQY 172 Query: 200 PAMSFDGKIILEEKNKVS---MAPDGNGGLYRALAAQNIVEDMEQRGIWSIHVYCVDNIL 256 P + + + L K K P G+G ++ +L ++ + +G + + DN+ Sbjct: 173 PRIVTEDFLPLPSKGKSGKDGWYPPGHGDVFPSLNNSGKLDILLAQGKEYVFIANSDNLG 232 Query: 257 VKVADPRFIGFCIQKGADCGAKVVEKTNPTEPVGVVCRVDGVYQVVEYSEISLATAQKRS 316 + D + + I + +V KT G + +G Q++E +++ + Sbjct: 233 A-IVDIKILNHLINNQNEYCMEVTPKTLADVKGGTLISYEGRVQLLEIAQVPDEHVNEFK 291 Query: 317 SDGRL-LFNAGNIANHFFTVPFLRDV 341 S + +FN N+ + + L + Sbjct: 292 SIEKFKIFNTNNLWVNLKAIKRLVEA 317 >2Q4J-A nrPDB Length = 469 Score = 197 bits (501), Expect = 9e-51, Method: Composition-based stats. Identities = 57/314 (18%), Positives = 109/314 (34%), Gaps = 30/314 (9%) Query: 37 LQAMNFEELNFFFQKAIEGFNQSSHQKNVDARMEP-----VPREVLGSATRDQDQLQAWE 91 L M+ E + F + + P VP E + ++D + + Sbjct: 18 LTEMSESEKSGFISLVSRYLSGEAQHIEWSKIQTPTDEIVVPYEKMTPVSQDVAETKNLL 77 Query: 92 SEGLFQISQNKVAVLLLAGGQGTRLGVAYPKGMYDVGLPSRKTLFQIQAERILKLQQVAE 151 + + GG GT +G PK + +V T + +I L Sbjct: 78 DKLVVLKL---------NGGLGTTMGCTGPKSVIEV--RDGLTFLDLIVIQIENLN---- 122 Query: 152 KYYGNKCIIPWYIMTSGRTMESTKEFFTKHKYFGLKKENVIFFQQGMLPAMSFDGKIILE 211 C +P +M S T + T + K+ ++ F Q P + D + Sbjct: 123 --NKYGCKVPLVLMNSFNTHDDTHKIVEKYTN---SNVDIHTFNQSKYPRVVADEFVPWP 177 Query: 212 EK---NKVSMAPDGNGGLYRALAAQNIVEDMEQRGIWSIHVYCVDNILVKVADPRFIGFC 268 K +K P G+G ++ AL ++ +G + V DN+ + D + Sbjct: 178 SKGKTDKEGWYPPGHGDVFPALMNSGKLDTFLSQGKEYVFVANSDNLGA-IVDLTILKHL 236 Query: 269 IQKGADCGAKVVEKTNPTEPVGVVCRVDGVYQVVEYSEISLATAQKRSSDGRL-LFNAGN 327 IQ + +V KT G + +G Q++E +++ + S + +FN N Sbjct: 237 IQNKNEYCMEVTPKTLADVKGGTLISYEGKVQLLEIAQVPDEHVNEFKSIEKFKIFNTNN 296 Query: 328 IANHFFTVPFLRDV 341 + + + L + Sbjct: 297 LWVNLKAIKKLVEA 310 >4M2B-A nrPDB Length = 505 Score = 173 bits (438), Expect = 2e-43, Method: Composition-based stats. Identities = 57/270 (21%), Positives = 104/270 (38%), Gaps = 29/270 (10%) Query: 79 SATRDQDQLQAWESEGL--FQISQNKVAVLLLAGGQGTRLGVAYPKGMYDVGLPSRKTLF 136 SA D L A +S + VL L GG GT +G+ K + +V KT Sbjct: 50 SAIMPVDSLDALDSLTIECDNAVLQSTVVLKLNGGLGTGMGLCDAKTLLEV--KDGKTFL 107 Query: 137 QIQAERILKLQQVAEKYYGNKCIIPWYIMTSGRTMESTKEFFT-KHKYFGLKKENVIFFQ 195 A ++ L+Q ++ + + +M S T STK F ++ + ++ + Sbjct: 108 DFTALQVQYLRQHCSEH------LRFMLMDSFNTSASTKSFLKARYPWLYQVFDSEVELM 161 Query: 196 QGMLPAMSFDGKII--LEEKNKVSMAPDGNGGLYRALAAQNIVEDMEQRGIWSIHVYCVD 253 Q +P + D E AP G+G +Y AL ++++ ++G + V D Sbjct: 162 QNQVPKILQDTLEPAAWAENPAYEWAPPGHGDIYTALYGSGKLQELVEQGYRYMFVSNGD 221 Query: 254 NILVKVADPRFIGFCIQKGADCGAKVVEKTNPTEPVGVVCR-------VDGVY------- 299 N+ + D R + + ++ D +V +T + G + R DG Sbjct: 222 NLGATI-DKRVLAYMEKEKIDFLMEVCRRTESDKKGGHLARQTVYVKGKDGQPDAEKRVL 280 Query: 300 QVVEYSEISLATAQKRSSDGRL-LFNAGNI 328 + E ++ A + + FN N+ Sbjct: 281 DLRESAQCPKADMESFQDINKYSFFNTNNL 310 >3OH0-A nrPDB Length = 641 Score = 77.1 bits (188), Expect = 2e-14, Method: Composition-based stats. Identities = 70/321 (21%), Positives = 113/321 (35%), Gaps = 44/321 (13%) Query: 2 NINDLKLTLSKAG--QEHLLRFW-------NELEEAQQVELYAELQAMNFEELNFFFQKA 52 N+ L+ L G Q HL W NE + A +LY M + + + Sbjct: 8 NLQALREELCTPGLDQGHLFEGWPETVDECNERQIALLTDLYM-FSNMYPGGVAQYIRNG 66 Query: 53 IEGFNQSSHQKNVDARMEPVPREVLGSATRDQDQLQAWESEGLFQISQNKVAVLLLAGGQ 112 E + S + + A P S R + A E+ G K +L+AGG Sbjct: 67 HELLARESEEVDFAALEMPPLIFEAPSLHRRTAERTALENAG--TAMLCKTVFVLVAGGL 124 Query: 113 GTRLGVAYPKGMYDVGLPSRKTLFQIQAERILKLQQVAEKYYGNKCIIPWYIMTSGRTME 172 G RLG + K V + T + A++ G + +P+ IMTS T + Sbjct: 125 GERLGYSSIKVSLPVETATNTTYL-------AYYLRWAQRVGGKE--VPFVIMTSDDTHD 175 Query: 173 STKEFFTKHKYFGLKKENVIFFQQGMLPAM-SFDGKIILEEKNKVSMAPDGNGGLYRALA 231 T + L+ N+ +QG + + L+E K+ P G+G ++ + Sbjct: 176 RTL---QLLRELQLEVPNLHVLKQGQVFCFADSAAHLALDETGKLLRKPHGHGDVHSLIY 232 Query: 232 ------------------AQNIVEDMEQRGIWSIHVYCVDNILVKVADPRFIGFCIQKGA 273 AQ +V D G SI N + P + + Sbjct: 233 NATVKRDVVPDSGDGTATAQPLVNDWLAAGYESIVFIQDTNAGATITIPISLALSAEHSL 292 Query: 274 DCGAKVVEKTNPTEPVGVVCR 294 D + P EP+G++CR Sbjct: 293 DMNFTCIP-RVPKEPIGLLCR 312 >6IGX-B nrPDB Length = 839 Score = 33.2 bits (74), Expect = 0.28, Method: Composition-based stats. Identities = 16/59 (27%), Positives = 24/59 (40%) Query: 3 INDLKLTLSKAGQEHLLRFWNELEEAQQVELYAELQAMNFEELNFFFQKAIEGFNQSSH 61 +ND + +A Q+HLL+ W E +EL L N E+ A+ S Sbjct: 268 LNDRSDAVKQAMQKHLLQGWLRFSEGNILELLHRLDVENSSEVAVSVLNALFSITPLSE 326 >4CVH-A nrPDB Length = 411 Score = 33.2 bits (74), Expect = 0.30, Method: Composition-based stats. Identities = 24/184 (13%), Positives = 67/184 (36%), Gaps = 24/184 (13%) Query: 103 VAVLLLAGGQGTRLGVAYPKGMYDVGLPSRKTLFQIQAERILKLQQVAEKYYGNKCIIPW 162 VA +L AGG G R+GV PK + + L + + ++ + + Sbjct: 7 VAAVLPAGGCGERMGVPTPKQFCPI---LERPLISYTLQALERVCWIKD----------I 53 Query: 163 YIMTSGRTMESTKEFFTKHKYFGLKKENVIFFQQGMLPAMSFDGKIILEEKNKVSMAPDG 222 + +G ME K K+++ K+ +++ ++ K + E++ ++ Sbjct: 54 VVAVTGENMEVMKSIIQKYQH---KRISLVEAGVTRHRSIFNGLKALAEDQINSKLSKPE 110 Query: 223 ----NGGLYRALAAQNIVEDMEQRGIWSIHVYCVDNILVKVADPRF---IGFCIQKGADC 275 + + R + ++ + + ++ V P + + +++ Sbjct: 111 VVIIHDAV-RPFVEEGVLLKVVTAAKEHGAAGAIRPLVSTVVSPSADGCLDYSLERARHR 169 Query: 276 GAKV 279 +++ Sbjct: 170 ASEM 173 >5V7X-A nrPDB Length = 752 Score = 31.7 bits (70), Expect = 0.77, Method: Composition-based stats. Identities = 14/66 (21%), Positives = 31/66 (46%), Gaps = 4/66 (6%) Query: 123 GMYDVGLPSRKTLFQIQAERILKLQQVA----EKYYGNKCIIPWYIMTSGRTMESTKEFF 178 G + + + +TLFQ++ R +L+ +A + Y G KC + +M + ++ Sbjct: 681 GRSKIFIRNPRTLFQLEDLRKQRLEDLATLIQKIYRGWKCRTHFLLMKGLNDIFEAQKAI 740 Query: 179 TKHKYF 184 H+ + Sbjct: 741 EWHEDY 746 >4E77-A nrPDB Length = 429 Score = 31.3 bits (69), Expect = 0.97, Method: Composition-based stats. Identities = 16/103 (15%), Positives = 31/103 (30%) Query: 351 HHVAQKKIPYVDTQGQLIKPDKPNGIKMEKFVFDIFQFAKKFVVYEVLREDEFSPLKNAD 410 H ++ + +G +KM + V D+ + E S ++ A Sbjct: 71 HPAIRQAVIEAVERGLSFGAPTEMEVKMAQLVTDLVPTMDMVRMVNSGTEATMSAIRLAR 130 Query: 411 SQNGKDNPTTARHALMSLHHCWVLNAGGHFIDENGSRLPAIPR 453 G+D C ++ AG + P +P Sbjct: 131 GYTGRDKIIKFEGCYHGHADCLLVKAGSGALTLGQPNSPGVPT 173 >2PX7-A nrPDB Length = 236 Score = 30.9 bits (68), Expect = 1.3, Method: Composition-based stats. Identities = 15/38 (39%), Positives = 20/38 (52%), Gaps = 4/38 (10%) Query: 102 KVAVLLLAGGQGTRLGVAYPKGMYDVGLPSRKTLFQIQ 139 +V+VL+ A G G RLG PK VG +TL + Sbjct: 25 EVSVLIPAAGNGLRLG-RGPKAFLQVG---GRTLLEWT 58 >4MYB-A nrPDB Length = 261 Score = 30.9 bits (68), Expect = 1.5, Method: Composition-based stats. Identities = 12/33 (36%), Positives = 18/33 (54%), Gaps = 2/33 (6%) Query: 105 VLLLAGGQGTRLGVAYPKGMYDVGLPSRKTLFQ 137 V++ A G GTR+ + PK Y L + KT+ Sbjct: 6 VIIPAAGIGTRMQLDIPKQYYK--LNNGKTILD 36 >4G3P-A nrPDB Length = 501 Score = 30.1 bits (66), Expect = 2.5, Method: Composition-based stats. Identities = 33/188 (17%), Positives = 66/188 (35%), Gaps = 23/188 (12%) Query: 101 NKVAVLLLAGGQGTRLGVAYPKGMYDVGLPSRKTLFQIQAERILKL--QQVAEKYYGNKC 158 AVL+LA G GTR+ PK ++ + + +++ I KL Q++ + Sbjct: 11 GDTAVLVLAAGPGTRMRSDTPKVLHTL---AGRSMLSHVLHAIAKLAPQRLIVVLGHDHQ 67 Query: 159 IIPWYIMTSGRTMESTKEFFTKHKYFGLKKENVIFFQQGMLPAMSFDGKIILEEKNKVSM 218 I + T+ T + + + G V+ LP + G +++ + Sbjct: 68 RIAPLVGELADTLGRTIDVALQDRPLG-TGHAVLC-GLSALPD-DYAGNVVVTSGDTP-- 122 Query: 219 APDGNGGLYRALAAQNIVEDMEQRGIWSIHVYCVDNILVKVADPRFIGFCIQKGADCGAK 278 L + + D+ V + + DP G ++ Sbjct: 123 -----------LLDADTLADLIATHRAVSAAVTV--LTTTLDDPFGYGRILRTQDHEVMA 169 Query: 279 VVEKTNPT 286 +VE+T+ T Sbjct: 170 IVEQTDAT 177 >2QKX-A nrPDB Length = 391 Score = 30.1 bits (66), Expect = 2.5, Method: Composition-based stats. Identities = 33/188 (17%), Positives = 66/188 (35%), Gaps = 23/188 (12%) Query: 101 NKVAVLLLAGGQGTRLGVAYPKGMYDVGLPSRKTLFQIQAERILKL--QQVAEKYYGNKC 158 AVL+LA G GTR+ PK ++ + + +++ I KL Q++ + Sbjct: 7 GDTAVLVLAAGPGTRMRSDTPKVLHTL---AGRSMLSHVLHAIAKLAPQRLIVVLGHDHQ 63 Query: 159 IIPWYIMTSGRTMESTKEFFTKHKYFGLKKENVIFFQQGMLPAMSFDGKIILEEKNKVSM 218 I + T+ T + + + G V+ LP + G +++ + Sbjct: 64 RIAPLVGELADTLGRTIDVALQDRPLG-TGHAVLC-GLSALPD-DYAGNVVVTSGDTP-- 118 Query: 219 APDGNGGLYRALAAQNIVEDMEQRGIWSIHVYCVDNILVKVADPRFIGFCIQKGADCGAK 278 L + + D+ V + + DP G ++ Sbjct: 119 -----------LLDADTLADLIATHRAVSAAVTV--LTTTLDDPFGYGRILRTQDHEVMA 165 Query: 279 VVEKTNPT 286 +VE+T+ T Sbjct: 166 IVEQTDAT 173 >2MPH-A nrPDB Length = 224 Score = 29.4 bits (64), Expect = 4.6, Method: Composition-based stats. Identities = 11/84 (13%), Positives = 34/84 (40%), Gaps = 6/84 (7%) Query: 3 INDLKLTLSKAGQEHLLRFWNELEEAQQVELYAELQAMNFEELNFFFQKAIEGFNQSSHQ 62 + ++K A ++HL+ +N L E ++ + + ++ + K ++ + Sbjct: 44 LGNIKNVAKTANKDHLVTAYNHLFETKRFKGTESISKVSEQ------VKNVKLNEDKPKE 97 Query: 63 KNVDARMEPVPREVLGSATRDQDQ 86 + ++ P + S + D+ Sbjct: 98 TKSEETLDEGPPKYTKSVLKKGDK 121 >4NAK-A nrPDB Length = 228 Score = 29.0 bits (63), Expect = 4.8, Method: Composition-based stats. Identities = 12/20 (60%), Positives = 17/20 (85%) Query: 103 VAVLLLAGGQGTRLGVAYPK 122 V+V+LLAGGQG R+ ++ PK Sbjct: 5 VSVILLAGGQGKRMKMSMPK 24 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.311 0.125 0.306 Lambda K H 0.267 0.0383 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 17,577,453 Number of Sequences: 36641 Number of extensions: 670580 Number of successful extensions: 1830 Number of sequences better than 10.0: 23 Number of HSP's better than 10.0 without gapping: 29 Number of HSP's successfully gapped in prelim test: 16 Number of HSP's that attempted gapping in prelim test: 1704 Number of HSP's gapped (non-prelim): 49 length of query: 522 length of database: 10,336,785 effective HSP length: 101 effective length of query: 421 effective length of database: 6,636,044 effective search space: 2793774524 effective search space used: 2793774524 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.4 bits) S2: 61 (28.2 bits)