BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q15274 (297 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 5AYY-A nrPDB 592 e-170 4I9A-A nrPDB 473 e-134 3C2O-A nrPDB 250 6e-67 5HUL-A nrPDB 180 7e-46 1X1O-A nrPDB 166 8e-42 1O4U-A nrPDB 155 2e-38 3TQV-A nrPDB 150 5e-37 3PAJ-A nrPDB 149 1e-36 3GNN-A nrPDB 147 5e-36 1QAP-A nrPDB 147 7e-36 2B7N-A nrPDB 144 4e-35 1QPQ-A nrPDB 130 7e-31 3L0G-A nrPDB 107 4e-24 2V81-A nrPDB 34 0.076 6NT5-A nrPDB 32 0.26 4QCC-A nrPDB 32 0.48 3O15-A nrPDB 30 1.4 3OVQ-A nrPDB 29 2.1 5ZI1-A nrPDB 29 2.2 4AF0-B nrPDB 28 4.1 3QE3-A nrPDB 28 4.9 6AO8-A nrPDB 27 8.0 3LOT-A nrPDB 27 8.1 >5AYY-A nrPDB Length = 305 Score = 592 bits (1526), Expect = e-170, Method: Compositional matrix adjust. Identities = 296/297 (99%), Positives = 296/297 (99%) Query: 1 MDAEGLALLLPPVTLAALVDSWLREDCPGLNYAALVSGAGPSQAALWAKSPGVLAGQPFF 60 MDAEGLALLLPPVTLAALVDSWLREDCPGLNYAALVSGAGPSQAALWAKSPGVLAGQPFF Sbjct: 1 MDAEGLALLLPPVTLAALVDSWLREDCPGLNYAALVSGAGPSQAALWAKSPGVLAGQPFF 60 Query: 61 DAIFTQLNCQVSWFLPEGSKLVPVARVAEVRGPAHCLLLGERVALNTLARCSGIASAAAA 120 DAIFTQLNCQVSWFLPEGSKLVPVARVAEVRGPAHCLLLGERVALNTLARCSGIASAAAA Sbjct: 61 DAIFTQLNCQVSWFLPEGSKLVPVARVAEVRGPAHCLLLGERVALNTLARCSGIASAAAA 120 Query: 121 AVEAARGAGWTGHVAGTRKTTPGFRLVEKYGLLVGGAASHRYDLGGLVMVKDNHVVAAGG 180 AVEAARGAGWTGHVAGTRKTTPGFRLVEKYGLLVGGAASHRYDLGGLVMVKDNHVVAAGG Sbjct: 121 AVEAARGAGWTGHVAGTRKTTPGFRLVEKYGLLVGGAASHRYDLGGLVMVKDNHVVAAGG 180 Query: 181 VEKAVRAARQAADFTLKVEVECSSLQEAVQAAEAGADLVLLDNFKPEELHPTATVLKAQF 240 VEKAVRAARQAADF LKVEVECSSLQEAVQAAEAGADLVLLDNFKPEELHPTATVLKAQF Sbjct: 181 VEKAVRAARQAADFALKVEVECSSLQEAVQAAEAGADLVLLDNFKPEELHPTATVLKAQF 240 Query: 241 PSVAVEASGGITLDNLPQFCGPHIDVISMGMLTQAAPALDFSLKLFAKEVAPVPKIH 297 PSVAVEASGGITLDNLPQFCGPHIDVISMGMLTQAAPALDFSLKLFAKEVAPVPKIH Sbjct: 241 PSVAVEASGGITLDNLPQFCGPHIDVISMGMLTQAAPALDFSLKLFAKEVAPVPKIH 297 >4I9A-A nrPDB Length = 288 Score = 473 bits (1218), Expect = e-134, Method: Compositional matrix adjust. Identities = 250/288 (86%), Positives = 268/288 (93%) Query: 1 MDAEGLALLLPPVTLAALVDSWLREDCPGLNYAALVSGAGPSQAALWAKSPGVLAGQPFF 60 MD EGLALLLPP TLA L DSWLREDCPGLN ALV+GA PSQA LWAKSPG+LAG+PFF Sbjct: 1 MDPEGLALLLPPATLATLADSWLREDCPGLNPVALVTGAAPSQAVLWAKSPGILAGRPFF 60 Query: 61 DAIFTQLNCQVSWFLPEGSKLVPVARVAEVRGPAHCLLLGERVALNTLARCSGIASAAAA 120 DAIF Q+NCQVSWFLPEGSKLVPVA+VAEVRGPAHCLLLGERVALN LARCSG+ASAAA Sbjct: 61 DAIFAQVNCQVSWFLPEGSKLVPVAKVAEVRGPAHCLLLGERVALNMLARCSGVASAAAT 120 Query: 121 AVEAARGAGWTGHVAGTRKTTPGFRLVEKYGLLVGGAASHRYDLGGLVMVKDNHVVAAGG 180 AVE ARG GW GHVAGTRKTTPGFRLVEKYGLLVGGA SHRYDLGGLVMVKDNHVVAAGG Sbjct: 121 AVETARGTGWAGHVAGTRKTTPGFRLVEKYGLLVGGATSHRYDLGGLVMVKDNHVVAAGG 180 Query: 181 VEKAVRAARQAADFTLKVEVECSSLQEAVQAAEAGADLVLLDNFKPEELHPTATVLKAQF 240 V++AV+ AR+AA+F LKVEVECSSLQEA++AAEAGADLVLLDNF+PEELHPTA LKAQF Sbjct: 181 VKQAVQGARRAANFALKVEVECSSLQEALEAAEAGADLVLLDNFRPEELHPTAAALKAQF 240 Query: 241 PSVAVEASGGITLDNLPQFCGPHIDVISMGMLTQAAPALDFSLKLFAK 288 P+V VEASGG+TLDNLPQFCGPHIDVIS+GMLTQAAPALDFSLKLFA+ Sbjct: 241 PTVGVEASGGVTLDNLPQFCGPHIDVISLGMLTQAAPALDFSLKLFAE 288 >3C2O-A nrPDB Length = 294 Score = 250 bits (638), Expect = 6e-67, Method: Compositional matrix adjust. Identities = 126/276 (45%), Positives = 167/276 (60%), Gaps = 9/276 (3%) Query: 19 VDSWLREDCPGLNYAALVSGAGPSQAALWAKSPGVLAGQPFFDAIFTQLNCQVSWFLPEG 78 V +WL ED P ++ V G+ +A L+ K G+L G PF +F Q QV W EG Sbjct: 17 VTNWLSEDVPSFDFGGYVVGSDLKEANLYCKQDGMLCGVPFAQEVFNQCELQVEWLFKEG 76 Query: 79 SKLVPVAR------VAEVRGPAHCLLLGERVALNTLARCSGIASAAAAAVEAARGAGWTG 132 S L P VA++ GPA +LL ER ALN L+R SGIA+A+ + AR G+ G Sbjct: 77 SFLEPSKNDSGKIVVAKITGPAKNILLAERTALNILSRSSGIATASHKIISLARSTGYKG 136 Query: 133 HVAGTRKTTPGFRLVEKYGLLVGGAASHRYDLGGLVMVKDNHVVAAGGVEKAVRAARQAA 192 +AGTRKTTPG R +EKY +LVGG +HRYDL +VM+KDNH+ A G + AV+ AR Sbjct: 137 TIAGTRKTTPGLRRLEKYSMLVGGCDTHRYDLSSMVMLKDNHIWATGSITNAVKNARAVC 196 Query: 193 DFTLKVEVECSSLQEAVQAAEAGADLVLLDNFKPEELHPTATVLKAQF---PSVAVEASG 249 F +K+EVEC S EA +A EAGAD+++LDNFK + L A LK ++ +E SG Sbjct: 197 GFAVKIEVECLSEDEATEAIEAGADVIMLDNFKGDGLKMCAQSLKNKWNGKKHFLLECSG 256 Query: 250 GITLDNLPQFCGPHIDVISMGMLTQAAPALDFSLKL 285 G+ LDNL ++ ID+ S + Q P +DFSLKL Sbjct: 257 GLNLDNLEEYLCDDIDIYSTSSIHQGTPVIDFSLKL 292 >5HUL-A nrPDB Length = 314 Score = 180 bits (456), Expect = 7e-46, Method: Compositional matrix adjust. Identities = 112/280 (40%), Positives = 154/280 (55%), Gaps = 10/280 (3%) Query: 10 LPPVTLAALVDSWLREDCPGLNYA--ALVSGAGPSQAALWAKSPGVLAGQPFFDAIFT-- 65 L P + + + LRED +Y+ A+ G ++ +L+AK GVLAG F +FT Sbjct: 33 LTPFQIDDTLKAALREDVHSEDYSTNAIFDHHGQAKVSLFAKEAGVLAGLTVFQRVFTLF 92 Query: 66 -QLNCQVSWFLPEGSKLVPVARVAEVRGPAHCLLLGERVALNTLARCSGIASAAAAAVEA 124 ++ Q +G +L V E+ G LL ERVALN L SGIAS AA VEA Sbjct: 93 DEVTFQNPHQFKDGDRLTSGDLVLEIIGSVRSLLTCERVALNFLQHLSGIASMTAAYVEA 152 Query: 125 ARGAGWTGHVAGTRKTTPGFRLVEKYGLLVGGAASHRYDLGGLVMVKDNHVVAAGGVEKA 184 V TRKTTP RL EKY + VGG +HR++L +M+KDNH+ A G V+KA Sbjct: 153 LGDDRIK--VFDTRKTTPNLRLFEKYAVRVGGGYNHRFNLSDAIMLKDNHIAAVGSVQKA 210 Query: 185 VRAARQAADFTLKVEVECSSLQEAVQAAEAGADLVLLDNFKPEELHPTATVLKAQFPSVA 244 + AR A F VEVE SL A +AA AG D+++LDN E++ T++ + Sbjct: 211 IAQARAYAPFVKMVEVEVESLAAAEEAAAAGVDIIMLDNMSLEQIEQAITLIAGR---SR 267 Query: 245 VEASGGITLDNLPQFCGPHIDVISMGMLTQAAPALDFSLK 284 +E SG I + + +F G ID +S G LT +A +LDFS+K Sbjct: 268 IECSGNIDMTTISRFRGLAIDYVSSGSLTHSAKSLDFSMK 307 >1X1O-A nrPDB Length = 286 Score = 166 bits (421), Expect = 8e-42, Method: Compositional matrix adjust. Identities = 116/267 (43%), Positives = 156/267 (58%), Gaps = 9/267 (3%) Query: 21 SWLREDCPGLNYAAL--VSGAGPSQAALWAKSPGVLAGQPFFDAIFTQLNCQVSW--FLP 76 +WLRED + +L V +A + AK GVLAG + +F + + ++ + Sbjct: 20 AWLREDLGQGDLTSLLVVPEDLEGEAVILAKEGGVLAGLWVAERVFALADPRTAFTPLVA 79 Query: 77 EGSKLVPVARVAEVRGPAHCLLLGERVALNTLARCSGIASAAAAAVEAARGAGWTGHVAG 136 EG+++ VA VRGP +L GER+ALN L R SGIA+ A VEA AG + Sbjct: 80 EGARVAEGTEVARVRGPLRGILAGERLALNLLQRLSGIATLTRAYVEAL--AGTKAQILD 137 Query: 137 TRKTTPGFRLVEKYGLLVGGAASHRYDLGGLVMVKDNHVVAAGGVEKAVRAARQAADFTL 196 TRKTTPG R +EKY + VGG +HRY L +++K+NHV AAGGV +AVR A+ A L Sbjct: 138 TRKTTPGLRALEKYAVRVGGGRNHRYGLFDGILLKENHVRAAGGVGEAVRRAKARAPHYL 197 Query: 197 KVEVECSSLQEAVQAAEAGADLVLLDNFKPEELHPTATVLKAQFPSVAVEASGGITLDNL 256 KVEVE SL+E +A EAGADL+LLDNF E L + + P +EASG +TL+ Sbjct: 198 KVEVEVRSLEELEEALEAGADLILLDNFPLEALREAVRRVGGRVP---LEASGNMTLERA 254 Query: 257 PQFCGPHIDVISMGMLTQAAPALDFSL 283 +D +S+G LT +A ALD SL Sbjct: 255 KAAAEAGVDYVSVGALTHSAKALDLSL 281 >1O4U-A nrPDB Length = 285 Score = 155 bits (393), Expect = 2e-38, Method: Compositional matrix adjust. Identities = 94/269 (34%), Positives = 146/269 (54%), Gaps = 5/269 (1%) Query: 18 LVDSWLREDCPGLNYAALVSGAGPSQAALWAKSPGVLAGQPFFDAIFTQLNCQVSWF-LP 76 L+ S+++ED L+ A+ + A L K+ V+A +F + +S F + Sbjct: 19 LLMSFVKEDEGKLDLASFPLRNTTAGAHLLLKTENVVASGIEVSRMFLEKMGLLSKFNVE 78 Query: 77 EGSKLVPVARVAEVRGPAHCLLLGERVALNTLARCSGIASAAAAAVEAARGAGWTGHVAG 136 +G L + E+ G + LL+ ER LN L+ +A+ E + A +A Sbjct: 79 DGEYLEGTGVIGEIEGNTYKLLVAERTLLNVLSVMFSVATTTRRFAEKLKHA----KIAA 134 Query: 137 TRKTTPGFRLVEKYGLLVGGAASHRYDLGGLVMVKDNHVVAAGGVEKAVRAARQAADFTL 196 TRK PG +++K ++ GG HR DL G VM+KDNH+ G E+AV+ R+ FT Sbjct: 135 TRKILPGLGVLQKIAVVHGGGDPHRLDLSGCVMIKDNHLKMYGSAERAVQEVRKIIPFTT 194 Query: 197 KVEVECSSLQEAVQAAEAGADLVLLDNFKPEELHPTATVLKAQFPSVAVEASGGITLDNL 256 K+EVE +L++A++A EAGAD+V+LDN PEE+ + +K P+V VE SGGIT +N+ Sbjct: 195 KIEVEVENLEDALRAVEAGADIVMLDNLSPEEVKDISRRIKDINPNVIVEVSGGITEENV 254 Query: 257 PQFCGPHIDVISMGMLTQAAPALDFSLKL 285 + +DVIS LT +D SL++ Sbjct: 255 SLYDFETVDVISSSRLTLQEVFVDLSLEI 283 >3TQV-A nrPDB Length = 287 Score = 150 bits (380), Expect = 5e-37, Method: Compositional matrix adjust. Identities = 90/278 (32%), Positives = 146/278 (52%), Gaps = 8/278 (2%) Query: 10 LPPVTLAALVDSWLREDCPGLNYAALVSGAGPSQAALWAKSPGVLAGQPFFDAIFTQL-- 67 +P + LV L ED + A ++ + A + +L GQ F + + QL Sbjct: 14 VPNDIVTRLVRESLAEDIATGDITAQLAEDIDTTAFCITREEMILCGQDFANEVINQLDK 73 Query: 68 NCQVSWFLPEGSKLVPVARVAEVRGPAHCLLLGERVALNTLARCSGIASAAAAAVEAARG 127 N Q++W + K+ AR+ E++G +L ER LN + SG A+ V+ Sbjct: 74 NIQITWLYSDAQKVPANARIFELKGNVRSILTAERTILNFIQMLSGTATVTNKLVKLI-- 131 Query: 128 AGWTGHVAGTRKTTPGFRLVEKYGLLVGGAASHRYDLGGLVMVKDNHVVAAGGVEKAVRA 187 + + + TRKT PGFRL +KY + GG +HR L ++K+NH+ +AGG+ KAV Sbjct: 132 SQYKTKLLDTRKTIPGFRLAQKYAVRCGGGFNHRIGLFDAYLIKENHIRSAGGIAKAVTK 191 Query: 188 ARQAADFTLKVEVECSSLQEAVQAAEAGADLVLLDNFKPEELHPTATVLKAQFPSVAVEA 247 A++ D VEVE ++L E QA A AD+V+LDNF E++ ++ + + VA+E Sbjct: 192 AKK-LDSNKVVEVEVTNLDELNQAIAAKADIVMLDNFSGEDIDIAVSIARGK---VALEV 247 Query: 248 SGGITLDNLPQFCGPHIDVISMGMLTQAAPALDFSLKL 285 SG I +++ +D IS+G +T+ A+D SL++ Sbjct: 248 SGNIDRNSIVAIAKTGVDFISVGAITKHIKAIDLSLQV 285 >3PAJ-A nrPDB Length = 320 Score = 149 bits (376), Expect = 1e-36, Method: Compositional matrix adjust. Identities = 102/284 (35%), Positives = 150/284 (52%), Gaps = 15/284 (5%) Query: 10 LPPVTLAALVDSWLREDCPGL------NYAALVSGAGPSQAALWAKSPGVLAGQPFFDAI 63 LP +++D+ L+ED G A+L+ S A + + GV GQ + D + Sbjct: 42 LPADITRSVIDT-LKEDLGGTLDPAADITASLIPADRISTATIITREAGVFCGQLWADEV 100 Query: 64 FTQLNCQVS--WFLPEGSKLVPVARVAEVRGPAHCLLLGERVALNTLARCSGIASAAAAA 121 F QL QVS W + +G L P + + GPA LL GER A+N + SG A+A A Sbjct: 101 FKQLGGQVSIEWHVQDGDTLTPNQTLCTLTGPARILLTGERNAMNFIQTLSGCATATARY 160 Query: 122 VEAARGAGWTGHVAGTRKTTPGFRLVEKYGLLVGGAASHRYDLGGLVMVKDNHVVAAGGV 181 V+ +G + TRKT PG R KY + GG +HR + ++K+NH++A GG+ Sbjct: 161 VQELKGTQC--RLLDTRKTIPGLRSALKYAVACGGGYNHRIGVFDAYLIKENHIIACGGI 218 Query: 182 EKAVRAARQAADFTLKVEVECSSLQEAVQAAEAGADLVLLDNFKPEELHPTATVLKAQFP 241 +A+ A+Q + VEVE +L E +A AGAD+++LDNF E + +K Sbjct: 219 RQAISTAKQ-LNPGKPVEVETETLAELEEAISAGADIIMLDNFSLEMMRE---AVKINAG 274 Query: 242 SVAVEASGGITLDNLPQFCGPHIDVISMGMLTQAAPALDFSLKL 285 A+E SG ITLDNL + +D IS+G LT+ ALD S++ Sbjct: 275 RAALENSGNITLDNLKECAETGVDYISVGALTKHLKALDLSMRF 318 >3GNN-A nrPDB Length = 298 Score = 147 bits (371), Expect = 5e-36, Method: Compositional matrix adjust. Identities = 96/266 (36%), Positives = 141/266 (53%), Gaps = 9/266 (3%) Query: 23 LREDC-PGLNYAALVSGAGPSQAALWAKSPGVLAGQPFFDAIFTQLN--CQVSWFLPEGS 79 L ED G LV P +A + + VL G P+FDA+ ++ +V W EG Sbjct: 37 LAEDVGSGDQTGRLVPDGAPRRARVIVREDAVLCGVPWFDAVVRAVDPSIEVDWRHREGD 96 Query: 80 KLVPVARVAEVRGPAHCLLLGERVALNTLARCSGIASAAAAAVEAARGAGWTGHVAGTRK 139 ++ + V E+RGPA LL ER ALN L SG+ASA V+ R A + TRK Sbjct: 97 RMSADSTVCELRGPARALLTAERNALNFLQLLSGVASATRQYVD--RIADTRARILDTRK 154 Query: 140 TTPGFRLVEKYGLLVGGAASHRYDLGGLVMVKDNHVVAAGGVEKAVRAARQAADFTLKVE 199 T PG RL +KY + VGG A+ R L +++K+NH+ AAGGV +A+ AA A + + V+ Sbjct: 155 TLPGLRLAQKYAVRVGGGANQRLALYAGILIKENHIAAAGGVGEALDAA-FALNAEVPVQ 213 Query: 200 VECSSLQEAVQAAEAGADLVLLDNFKPEELHPTATVLKAQFPSVAVEASGGITLDNLPQF 259 +E +L + A GA VLLDNF + + V + + +E SGG+ D + Sbjct: 214 IEVETLDQLRTALAHGARSVLLDNFTLDMMRDAVRVTEGR---AVLEVSGGVNFDTVRAI 270 Query: 260 CGPHIDVISMGMLTQAAPALDFSLKL 285 +D IS+G LT+ A D+S+++ Sbjct: 271 AETGVDRISIGALTKDVRATDYSMRI 296 >1QAP-A nrPDB Length = 296 Score = 147 bits (370), Expect = 7e-36, Method: Compositional matrix adjust. Identities = 90/260 (34%), Positives = 137/260 (52%), Gaps = 17/260 (6%) Query: 33 AALVSGAGPSQAALWAKSPGVLAGQPFFDAIFTQL---NCQVSWFLPEGSKLVPVARVAE 89 A L+ + A + + GV G+ + + +F QL + +++W + +G + V E Sbjct: 46 AQLLPADTQAHATVITREDGVFCGKRWVEEVFIQLAGDDVRLTWHVDDGDAIHANQTVFE 105 Query: 90 VRGPAHCLLLGERVALNTLARCSGIASAAAAAVEAARGAGWTGHVAGTRKTTPGFRLVEK 149 ++GPA LL GER ALN + SG+AS V AG + TRKT PG R K Sbjct: 106 LQGPARVLLTGERTALNFVQTLSGVASEVRRYVGLL--AGTQTQLLDTRKTLPGLRTALK 163 Query: 150 YGLLVGGAASHRYDLGGLVMVKDNHVVAAGGVEKAVRAARQAADFTLK----VEVECSSL 205 Y +L GG A+HR L ++K+NH++A+G V +AV A F L VEVE +L Sbjct: 164 YAVLCGGGANHRLGLTDAFLIKENHIIASGSVRQAVEKA-----FWLHPDVPVEVEVENL 218 Query: 206 QEAVQAAEAGADLVLLDNFKPEELHPTATVLKAQFPSVAVEASGGITLDNLPQFCGPHID 265 E A +AGAD+++LDNF +++ + Q +E SG +T + L +F +D Sbjct: 219 DELDDALKAGADIIMLDNFNTDQMREAVKRVNGQ---ARLEVSGNVTAETLREFAETGVD 275 Query: 266 VISMGMLTQAAPALDFSLKL 285 IS+G LT+ ALD S++ Sbjct: 276 FISVGALTKHVRALDLSMRF 295 >2B7N-A nrPDB Length = 273 Score = 144 bits (364), Expect = 4e-35, Method: Compositional matrix adjust. Identities = 86/274 (31%), Positives = 137/274 (50%), Gaps = 3/274 (1%) Query: 13 VTLAALVDSWLREDC-PGLNYAALVSGAGPSQAALWAKSPGVLAGQPFFDAIFTQLNCQV 71 + + ++ L+ED G + ++ + A + AK GV +G+ + + + Sbjct: 1 MEIRTFLERALKEDLGHGDLFERVLEKDFKATAFVRAKQEGVFSGEKYALELLEMTGIEC 60 Query: 72 SWFLPEGSKLVPVARVAEVRGPAHCLLLGERVALNTLARCSGIASAAAAAVEAARGAGWT 131 + + + P + E+RG LL ER LN L SGIA+ + VEA Sbjct: 61 VQTIKDKERFKPKDALMEIRGDFSMLLKVERTLLNLLQHSSGIATLTSRFVEALNSHKV- 119 Query: 132 GHVAGTRKTTPGFRLVEKYGLLVGGAASHRYDLGGLVMVKDNHVVAAGGVEKAVRAARQA 191 + TRKT P R+ EKY +L GGA++HR L +M+KD H+ ++ + AR+ Sbjct: 120 -RLLDTRKTRPLLRIFEKYSVLNGGASNHRLGLDDALMLKDTHLRHVKDLKSFLTHARKN 178 Query: 192 ADFTLKVEVECSSLQEAVQAAEAGADLVLLDNFKPEELHPTATVLKAQFPSVAVEASGGI 251 FT K+E+EC S +EA A AGAD+V+ DN E A A +P V +EASG I Sbjct: 179 LPFTAKIEIECESFEEAKNAMNAGADIVMCDNLSVLETKEIAAYRDAHYPFVLLEASGNI 238 Query: 252 TLDNLPQFCGPHIDVISMGMLTQAAPALDFSLKL 285 +L+++ + +D IS+G L A +D +K+ Sbjct: 239 SLESINAYAKSGVDAISVGALIHQATFIDMHMKM 272 >1QPQ-A nrPDB Length = 284 Score = 130 bits (327), Expect = 7e-31, Method: Compositional matrix adjust. Identities = 91/273 (33%), Positives = 135/273 (49%), Gaps = 16/273 (5%) Query: 23 LREDC---PGLNYAALVSGAGPSQAALWAKSPGVLAGQPFFDAIFTQLN-------CQVS 72 L ED P + A V + + A+L + GV+AG D LN +V Sbjct: 18 LDEDLRYGPDVTTLATVPASATTTASLVTREAGVVAG---LDVALLTLNEVLGTNGYRVL 74 Query: 73 WFLPEGSKLVPVARVAEVRGPAHCLLLGERVALNTLARCSGIASAAAAAVEAARGAGWTG 132 + +G+++ P + + LL ER LN + SGIA+A AA V+A RG Sbjct: 75 DRVEDGARVPPGEALMTLEAQTRGLLTAERTMLNLVGHLSGIATATAAWVDAVRGT--KA 132 Query: 133 HVAGTRKTTPGFRLVEKYGLLVGGAASHRYDLGGLVMVKDNHVVAAGGVEKAVRAARQAA 192 + TRKT PG R ++KY + GG +HR LG ++KDNHV AAG V A+RA R AA Sbjct: 133 KIRDTRKTLPGLRALQKYAVRTGGGVNHRLGLGDAALIKDNHVAAAGSVVDALRAVRNAA 192 Query: 193 DFTLKVEVECSSLQEAVQAAEAGADLVLLDNFKPEELHPTATVLKAQFPSVAVEASGGIT 252 L EVE SL++ +L+LLDNF + ++ P+V +E+SGG++ Sbjct: 193 P-DLPCEVEVDSLEQLDAVLPEKPELILLDNFAVWQTQTAVQRRDSRAPTVMLESSGGLS 251 Query: 253 LDNLPQFCGPHIDVISMGMLTQAAPALDFSLKL 285 L + +D +++G LT + LD L + Sbjct: 252 LQTAATYAETGVDYLAVGALTHSVRVLDIGLDM 284 >3L0G-A nrPDB Length = 300 Score = 107 bits (268), Expect = 4e-24, Method: Compositional matrix adjust. Identities = 67/246 (27%), Positives = 116/246 (47%), Gaps = 14/246 (5%) Query: 45 ALWAKSPGVLAGQPFFDAIFTQLNCQVSWFLPEGSKLVPVARVAEVRGPAHCLLL--GER 102 A+ + V+ G P + +F V + + + + V G A + L ER Sbjct: 58 AINTRENLVVCGIPILEEVFNMNKEHVKYEIHKKDGDITGKNSTLVSGEALAIYLLPIER 117 Query: 103 VALNTLARCSGIASAAAAAVEAARGAGWTGHVAGTRKTTPGFRLVEKYGLLVGGAASHRY 162 V LN + SGIAS V+ G + TRKTTPG R+++KY + +GG S+R Sbjct: 118 VILNFIQHASGIASITRQFVDEVSGTKV--KIRSTRKTTPGLRMLDKYSVCIGGGESYRD 175 Query: 163 DLGGLVMVKDNHVVAAGGVEKAVRAARQAADFTLKVE---VECSSLQEAVQAAEAGADLV 219 +L V++KDNH+ + G + A++ R+ LK E +EC ++ + ++ D++ Sbjct: 176 NLCDGVLIKDNHIASCGSITLAIQRLRK----NLKNEYIAIECDNISQVEESLSNNVDMI 231 Query: 220 LLDNFKPEELHPTATVLKAQFPSVAVEASGGITLDNLPQFCGPHIDVISMGMLTQAAPAL 279 LLDN E+ ++ + +E SG + + N+ +D IS+G +T + Sbjct: 232 LLDNMSISEIKKAVDIVNGKS---VLEVSGCVNIRNVRNIALTGVDYISIGCITNSFQNK 288 Query: 280 DFSLKL 285 D L + Sbjct: 289 DIGLDI 294 >2V81-A nrPDB Length = 212 Score = 34.3 bits (77), Expect = 0.076, Method: Compositional matrix adjust. Identities = 27/75 (36%), Positives = 40/75 (53%), Gaps = 8/75 (10%) Query: 189 RQAADFTLKVEVECSSLQEAVQAAEAGADLVLL---DNFKPEELHPTATVLKAQFPS-VA 244 R+A + + V C++ EA A EAGA + + F P+ + LKA PS +A Sbjct: 95 RRAVGYGMTVCPGCATATEAFTALEAGAQALKIFPSSAFGPQYIK----ALKAVLPSDIA 150 Query: 245 VEASGGITLDNLPQF 259 V A GG+T +NL Q+ Sbjct: 151 VFAVGGVTPENLAQW 165 >6NT5-A nrPDB Length = 385 Score = 32.3 bits (72), Expect = 0.26, Method: Compositional matrix adjust. Identities = 49/188 (26%), Positives = 72/188 (38%), Gaps = 27/188 (14%) Query: 98 LLGERVALNTLARCSGIASAAAAAV------EAARGAGWTGHVAGTRKTTPGFR-----L 146 LLG ALN L G+A A +AV A G W+ ++ R P + Sbjct: 123 LLGLSQALNILLGLKGLAPAEISAVCEKGNFNVAHGLAWSYYIGYLRLILPELQARIRTY 182 Query: 147 VEKYGLLVGGAASHR-YDLGGL-VMVKDNHVVAAGGVEKAVRAARQAADFT-LKVEVECS 203 + Y L+ GA S R Y L L V DN +A + + +Q D +K V + Sbjct: 183 NQHYNNLLRGAVSQRLYILLPLDCGVPDNLSMADPNIRFLDKLPQQTGDRAGIKDRVYSN 242 Query: 204 SLQEAVQAAEAGADLVLLDNFKPEELHPTATVLKAQFPSVAVEASGGITLDNLPQ---FC 260 S+ E ++ + VL AT L+ F +G D L Q FC Sbjct: 243 SIYELLENGQRAGTCVL----------EYATPLQTLFAMSQYSQAGFSREDRLEQAKLFC 292 Query: 261 GPHIDVIS 268 D+++ Sbjct: 293 RTLEDILA 300 >4QCC-A nrPDB Length = 291 Score = 31.6 bits (70), Expect = 0.48, Method: Compositional matrix adjust. Identities = 27/75 (36%), Positives = 40/75 (53%), Gaps = 8/75 (10%) Query: 189 RQAADFTLKVEVECSSLQEAVQAAEAGADLVLL---DNFKPEELHPTATVLKAQFPS-VA 244 R+A + + V C++ EA A EAGA + + F P+ + LKA PS +A Sbjct: 95 RRAVGYGMTVCPGCATATEAFTALEAGAQALKIFPSSAFGPQYIK----ALKAVLPSDIA 150 Query: 245 VEASGGITLDNLPQF 259 V A GG+T +NL Q+ Sbjct: 151 VFAVGGVTPENLAQW 165 >3O15-A nrPDB Length = 235 Score = 30.0 bits (66), Expect = 1.4, Method: Compositional matrix adjust. Identities = 33/117 (28%), Positives = 46/117 (39%), Gaps = 13/117 (11%) Query: 183 KAVRAARQAADFTLKVEVECSSLQEAVQAAEAGADLVLLDNFKPEELHPTA--------- 233 K VRAA D L V ++ E QA E GAD V L P E Sbjct: 116 KEVRAA--IGDMILGVS--AHTMSEVKQAEEDGADYVGLGPIYPTETKKDTRAVQGVSLI 171 Query: 234 TVLKAQFPSVAVEASGGITLDNLPQFCGPHIDVISMGMLTQAAPALDFSLKLFAKEV 290 ++ Q S+ + GGIT+DN D +SM A + + + F +E+ Sbjct: 172 EAVRRQGISIPIVGIGGITIDNAAPVIQAGADGVSMISAISQAEDPESAARKFREEI 228 >3OVQ-A nrPDB Length = 228 Score = 29.3 bits (64), Expect = 2.1, Method: Compositional matrix adjust. Identities = 11/30 (36%), Positives = 18/30 (60%) Query: 227 EELHPTATVLKAQFPSVAVEASGGITLDNL 256 E++ P L+ QFPS+ +E GG+ D + Sbjct: 154 EDMMPKVHWLRTQFPSLDIEVDGGVGPDTV 183 >5ZI1-A nrPDB Length = 609 Score = 29.3 bits (64), Expect = 2.2, Method: Compositional matrix adjust. Identities = 15/39 (38%), Positives = 17/39 (43%) Query: 126 RGAGWTGHVAGTRKTTPGFRLVEKYGLLVGGAASHRYDL 164 R A WTGH T+ T YG G SH +DL Sbjct: 311 RFAIWTGHSVVTQYTKSTTENTFNYGTSSGSTLSHTFDL 349 >4AF0-B nrPDB Length = 556 Score = 28.5 bits (62), Expect = 4.1, Method: Compositional matrix adjust. Identities = 17/62 (27%), Positives = 31/62 (50%), Gaps = 2/62 (3%) Query: 212 AEAGADLVLLDNFKPEELHPTATV--LKAQFPSVAVEASGGITLDNLPQFCGPHIDVISM 269 AEAG D+V+LD+ + ++ + +K +P + V A +T + Q D + + Sbjct: 290 AEAGLDVVVLDSSQGNSVYQIEFIKWIKQTYPKIDVIAGNVVTREQAAQLIAAGADGLRI 349 Query: 270 GM 271 GM Sbjct: 350 GM 351 >3QE3-A nrPDB Length = 355 Score = 28.1 bits (61), Expect = 4.9, Method: Compositional matrix adjust. Identities = 15/41 (36%), Positives = 21/41 (51%), Gaps = 1/41 (2%) Query: 210 QAAEAGADLVL-LDNFKPEELHPTATVLKAQFPSVAVEASG 249 +A E GAD +L + N PEE+ L P V +E +G Sbjct: 210 KAKEVGADFILEISNESPEEIAKKVEGLLGSKPEVTIECTG 250 >6AO8-A nrPDB Length = 580 Score = 27.3 bits (59), Expect = 8.0, Method: Compositional matrix adjust. Identities = 12/35 (34%), Positives = 21/35 (60%) Query: 205 LQEAVQAAEAGADLVLLDNFKPEELHPTATVLKAQ 239 +Q+ + + GA +V LD FK +E P A +++ Q Sbjct: 280 VQKGLAVEDDGAKVVFLDEFKNKEGEPAAFIVQKQ 314 >3LOT-A nrPDB Length = 314 Score = 27.3 bits (59), Expect = 8.1, Method: Compositional matrix adjust. Identities = 14/31 (45%), Positives = 21/31 (67%) Query: 205 LQEAVQAAEAGADLVLLDNFKPEELHPTATV 235 ++EAV+AAEAGA +V + P++ PT V Sbjct: 35 VEEAVKAAEAGAGMVHIHARDPKDGRPTTDV 65 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 5AYY-A nrPDB 418 e-117 4I9A-A nrPDB 358 2e-99 3C2O-A nrPDB 341 3e-94 3PAJ-A nrPDB 321 2e-88 2B7N-A nrPDB 316 1e-86 1QAP-A nrPDB 314 3e-86 3TQV-A nrPDB 314 3e-86 5HUL-A nrPDB 311 2e-85 3GNN-A nrPDB 291 2e-79 1O4U-A nrPDB 285 2e-77 1X1O-A nrPDB 282 1e-76 1QPQ-A nrPDB 282 1e-76 3L0G-A nrPDB 276 7e-75 Sequences not found previously or not previously below threshold: 2I14-A nrPDB 60 1e-09 1XI3-A nrPDB 38 0.004 1YTE-A nrPDB 36 0.017 5UQG-A nrPDB 35 0.038 1ZFJ-A nrPDB 34 0.061 3O15-A nrPDB 33 0.16 3T55-A nrPDB 33 0.18 4FXS-A nrPDB 33 0.19 3OVQ-A nrPDB 33 0.21 3QE3-A nrPDB 32 0.42 4QJ1-A nrPDB 32 0.45 3F4W-A nrPDB 31 0.54 6I0M-A nrPDB 31 0.58 3FFS-A nrPDB 31 0.59 1VRD-A nrPDB 31 0.68 4FEZ-A nrPDB 30 1.1 2F7F-A nrPDB 30 1.6 4DZA-A nrPDB 30 1.8 6HUL-A nrPDB 29 2.3 1JCN-A nrPDB 29 3.2 2JFH-A nrPDB 28 4.0 4LPS-A nrPDB 28 4.1 5UMF-A nrPDB 28 4.6 1V77-A nrPDB 28 4.6 6BMA-A nrPDB 28 5.4 1H1Z-A nrPDB 28 6.1 3INP-A nrPDB 28 6.2 4YUB-A nrPDB 28 7.2 2I71-A nrPDB 27 7.5 3Q94-A nrPDB 27 7.7 6MWQ-A nrPDB 27 8.3 >5AYY-A nrPDB Length = 305 Score = 418 bits (1075), Expect = e-117, Method: Composition-based stats. Identities = 296/297 (99%), Positives = 296/297 (99%) Query: 1 MDAEGLALLLPPVTLAALVDSWLREDCPGLNYAALVSGAGPSQAALWAKSPGVLAGQPFF 60 MDAEGLALLLPPVTLAALVDSWLREDCPGLNYAALVSGAGPSQAALWAKSPGVLAGQPFF Sbjct: 1 MDAEGLALLLPPVTLAALVDSWLREDCPGLNYAALVSGAGPSQAALWAKSPGVLAGQPFF 60 Query: 61 DAIFTQLNCQVSWFLPEGSKLVPVARVAEVRGPAHCLLLGERVALNTLARCSGIASAAAA 120 DAIFTQLNCQVSWFLPEGSKLVPVARVAEVRGPAHCLLLGERVALNTLARCSGIASAAAA Sbjct: 61 DAIFTQLNCQVSWFLPEGSKLVPVARVAEVRGPAHCLLLGERVALNTLARCSGIASAAAA 120 Query: 121 AVEAARGAGWTGHVAGTRKTTPGFRLVEKYGLLVGGAASHRYDLGGLVMVKDNHVVAAGG 180 AVEAARGAGWTGHVAGTRKTTPGFRLVEKYGLLVGGAASHRYDLGGLVMVKDNHVVAAGG Sbjct: 121 AVEAARGAGWTGHVAGTRKTTPGFRLVEKYGLLVGGAASHRYDLGGLVMVKDNHVVAAGG 180 Query: 181 VEKAVRAARQAADFTLKVEVECSSLQEAVQAAEAGADLVLLDNFKPEELHPTATVLKAQF 240 VEKAVRAARQAADF LKVEVECSSLQEAVQAAEAGADLVLLDNFKPEELHPTATVLKAQF Sbjct: 181 VEKAVRAARQAADFALKVEVECSSLQEAVQAAEAGADLVLLDNFKPEELHPTATVLKAQF 240 Query: 241 PSVAVEASGGITLDNLPQFCGPHIDVISMGMLTQAAPALDFSLKLFAKEVAPVPKIH 297 PSVAVEASGGITLDNLPQFCGPHIDVISMGMLTQAAPALDFSLKLFAKEVAPVPKIH Sbjct: 241 PSVAVEASGGITLDNLPQFCGPHIDVISMGMLTQAAPALDFSLKLFAKEVAPVPKIH 297 >4I9A-A nrPDB Length = 288 Score = 358 bits (918), Expect = 2e-99, Method: Composition-based stats. Identities = 250/288 (86%), Positives = 268/288 (93%) Query: 1 MDAEGLALLLPPVTLAALVDSWLREDCPGLNYAALVSGAGPSQAALWAKSPGVLAGQPFF 60 MD EGLALLLPP TLA L DSWLREDCPGLN ALV+GA PSQA LWAKSPG+LAG+PFF Sbjct: 1 MDPEGLALLLPPATLATLADSWLREDCPGLNPVALVTGAAPSQAVLWAKSPGILAGRPFF 60 Query: 61 DAIFTQLNCQVSWFLPEGSKLVPVARVAEVRGPAHCLLLGERVALNTLARCSGIASAAAA 120 DAIF Q+NCQVSWFLPEGSKLVPVA+VAEVRGPAHCLLLGERVALN LARCSG+ASAAA Sbjct: 61 DAIFAQVNCQVSWFLPEGSKLVPVAKVAEVRGPAHCLLLGERVALNMLARCSGVASAAAT 120 Query: 121 AVEAARGAGWTGHVAGTRKTTPGFRLVEKYGLLVGGAASHRYDLGGLVMVKDNHVVAAGG 180 AVE ARG GW GHVAGTRKTTPGFRLVEKYGLLVGGA SHRYDLGGLVMVKDNHVVAAGG Sbjct: 121 AVETARGTGWAGHVAGTRKTTPGFRLVEKYGLLVGGATSHRYDLGGLVMVKDNHVVAAGG 180 Query: 181 VEKAVRAARQAADFTLKVEVECSSLQEAVQAAEAGADLVLLDNFKPEELHPTATVLKAQF 240 V++AV+ AR+AA+F LKVEVECSSLQEA++AAEAGADLVLLDNF+PEELHPTA LKAQF Sbjct: 181 VKQAVQGARRAANFALKVEVECSSLQEALEAAEAGADLVLLDNFRPEELHPTAAALKAQF 240 Query: 241 PSVAVEASGGITLDNLPQFCGPHIDVISMGMLTQAAPALDFSLKLFAK 288 P+V VEASGG+TLDNLPQFCGPHIDVIS+GMLTQAAPALDFSLKLFA+ Sbjct: 241 PTVGVEASGGVTLDNLPQFCGPHIDVISLGMLTQAAPALDFSLKLFAE 288 >3C2O-A nrPDB Length = 294 Score = 341 bits (874), Expect = 3e-94, Method: Composition-based stats. Identities = 126/276 (45%), Positives = 167/276 (60%), Gaps = 9/276 (3%) Query: 19 VDSWLREDCPGLNYAALVSGAGPSQAALWAKSPGVLAGQPFFDAIFTQLNCQVSWFLPEG 78 V +WL ED P ++ V G+ +A L+ K G+L G PF +F Q QV W EG Sbjct: 17 VTNWLSEDVPSFDFGGYVVGSDLKEANLYCKQDGMLCGVPFAQEVFNQCELQVEWLFKEG 76 Query: 79 SKLVPVAR------VAEVRGPAHCLLLGERVALNTLARCSGIASAAAAAVEAARGAGWTG 132 S L P VA++ GPA +LL ER ALN L+R SGIA+A+ + AR G+ G Sbjct: 77 SFLEPSKNDSGKIVVAKITGPAKNILLAERTALNILSRSSGIATASHKIISLARSTGYKG 136 Query: 133 HVAGTRKTTPGFRLVEKYGLLVGGAASHRYDLGGLVMVKDNHVVAAGGVEKAVRAARQAA 192 +AGTRKTTPG R +EKY +LVGG +HRYDL +VM+KDNH+ A G + AV+ AR Sbjct: 137 TIAGTRKTTPGLRRLEKYSMLVGGCDTHRYDLSSMVMLKDNHIWATGSITNAVKNARAVC 196 Query: 193 DFTLKVEVECSSLQEAVQAAEAGADLVLLDNFKPEELHPTATVLKAQF---PSVAVEASG 249 F +K+EVEC S EA +A EAGAD+++LDNFK + L A LK ++ +E SG Sbjct: 197 GFAVKIEVECLSEDEATEAIEAGADVIMLDNFKGDGLKMCAQSLKNKWNGKKHFLLECSG 256 Query: 250 GITLDNLPQFCGPHIDVISMGMLTQAAPALDFSLKL 285 G+ LDNL ++ ID+ S + Q P +DFSLKL Sbjct: 257 GLNLDNLEEYLCDDIDIYSTSSIHQGTPVIDFSLKL 292 >3PAJ-A nrPDB Length = 320 Score = 321 bits (824), Expect = 2e-88, Method: Composition-based stats. Identities = 101/284 (35%), Positives = 150/284 (52%), Gaps = 15/284 (5%) Query: 10 LPPVTLAALVDSWLREDCPG------LNYAALVSGAGPSQAALWAKSPGVLAGQPFFDAI 63 LP +++D+ L+ED G A+L+ S A + + GV GQ + D + Sbjct: 42 LPADITRSVIDT-LKEDLGGTLDPAADITASLIPADRISTATIITREAGVFCGQLWADEV 100 Query: 64 FTQLNCQVS--WFLPEGSKLVPVARVAEVRGPAHCLLLGERVALNTLARCSGIASAAAAA 121 F QL QVS W + +G L P + + GPA LL GER A+N + SG A+A A Sbjct: 101 FKQLGGQVSIEWHVQDGDTLTPNQTLCTLTGPARILLTGERNAMNFIQTLSGCATATARY 160 Query: 122 VEAARGAGWTGHVAGTRKTTPGFRLVEKYGLLVGGAASHRYDLGGLVMVKDNHVVAAGGV 181 V+ +G + TRKT PG R KY + GG +HR + ++K+NH++A GG+ Sbjct: 161 VQELKGTQC--RLLDTRKTIPGLRSALKYAVACGGGYNHRIGVFDAYLIKENHIIACGGI 218 Query: 182 EKAVRAARQAADFTLKVEVECSSLQEAVQAAEAGADLVLLDNFKPEELHPTATVLKAQFP 241 +A+ A+Q + VEVE +L E +A AGAD+++LDNF E + + + Sbjct: 219 RQAISTAKQ-LNPGKPVEVETETLAELEEAISAGADIIMLDNFSLEMMREAVKINAGR-- 275 Query: 242 SVAVEASGGITLDNLPQFCGPHIDVISMGMLTQAAPALDFSLKL 285 A+E SG ITLDNL + +D IS+G LT+ ALD S++ Sbjct: 276 -AALENSGNITLDNLKECAETGVDYISVGALTKHLKALDLSMRF 318 >2B7N-A nrPDB Length = 273 Score = 316 bits (809), Expect = 1e-86, Method: Composition-based stats. Identities = 86/274 (31%), Positives = 137/274 (50%), Gaps = 3/274 (1%) Query: 13 VTLAALVDSWLREDC-PGLNYAALVSGAGPSQAALWAKSPGVLAGQPFFDAIFTQLNCQV 71 + + ++ L+ED G + ++ + A + AK GV +G+ + + + Sbjct: 1 MEIRTFLERALKEDLGHGDLFERVLEKDFKATAFVRAKQEGVFSGEKYALELLEMTGIEC 60 Query: 72 SWFLPEGSKLVPVARVAEVRGPAHCLLLGERVALNTLARCSGIASAAAAAVEAARGAGWT 131 + + + P + E+RG LL ER LN L SGIA+ + VEA Sbjct: 61 VQTIKDKERFKPKDALMEIRGDFSMLLKVERTLLNLLQHSSGIATLTSRFVEALNSHKV- 119 Query: 132 GHVAGTRKTTPGFRLVEKYGLLVGGAASHRYDLGGLVMVKDNHVVAAGGVEKAVRAARQA 191 + TRKT P R+ EKY +L GGA++HR L +M+KD H+ ++ + AR+ Sbjct: 120 -RLLDTRKTRPLLRIFEKYSVLNGGASNHRLGLDDALMLKDTHLRHVKDLKSFLTHARKN 178 Query: 192 ADFTLKVEVECSSLQEAVQAAEAGADLVLLDNFKPEELHPTATVLKAQFPSVAVEASGGI 251 FT K+E+EC S +EA A AGAD+V+ DN E A A +P V +EASG I Sbjct: 179 LPFTAKIEIECESFEEAKNAMNAGADIVMCDNLSVLETKEIAAYRDAHYPFVLLEASGNI 238 Query: 252 TLDNLPQFCGPHIDVISMGMLTQAAPALDFSLKL 285 +L+++ + +D IS+G L A +D +K+ Sbjct: 239 SLESINAYAKSGVDAISVGALIHQATFIDMHMKM 272 >1QAP-A nrPDB Length = 296 Score = 314 bits (805), Expect = 3e-86, Method: Composition-based stats. Identities = 95/283 (33%), Positives = 145/283 (51%), Gaps = 15/283 (5%) Query: 12 PVTLAALVDSWLREDCPG------LNYAALVSGAGPSQAALWAKSPGVLAGQPFFDAIFT 65 + + A V LRED G A L+ + A + + GV G+ + + +F Sbjct: 19 NLDIPAAVAQALREDLGGEVDAGNDITAQLLPADTQAHATVITREDGVFCGKRWVEEVFI 78 Query: 66 QL---NCQVSWFLPEGSKLVPVARVAEVRGPAHCLLLGERVALNTLARCSGIASAAAAAV 122 QL + +++W + +G + V E++GPA LL GER ALN + SG+AS V Sbjct: 79 QLAGDDVRLTWHVDDGDAIHANQTVFELQGPARVLLTGERTALNFVQTLSGVASEVRRYV 138 Query: 123 EAARGAGWTGHVAGTRKTTPGFRLVEKYGLLVGGAASHRYDLGGLVMVKDNHVVAAGGVE 182 AG + TRKT PG R KY +L GG A+HR L ++K+NH++A+G V Sbjct: 139 GLL--AGTQTQLLDTRKTLPGLRTALKYAVLCGGGANHRLGLTDAFLIKENHIIASGSVR 196 Query: 183 KAVRAARQAADFTLKVEVECSSLQEAVQAAEAGADLVLLDNFKPEELHPTATVLKAQFPS 242 +AV A + VEVE +L E A +AGAD+++LDNF +++ + Q Sbjct: 197 QAVEKA-FWLHPDVPVEVEVENLDELDDALKAGADIIMLDNFNTDQMREAVKRVNGQ--- 252 Query: 243 VAVEASGGITLDNLPQFCGPHIDVISMGMLTQAAPALDFSLKL 285 +E SG +T + L +F +D IS+G LT+ ALD S++ Sbjct: 253 ARLEVSGNVTAETLREFAETGVDFISVGALTKHVRALDLSMRF 295 >3TQV-A nrPDB Length = 287 Score = 314 bits (804), Expect = 3e-86, Method: Composition-based stats. Identities = 90/278 (32%), Positives = 146/278 (52%), Gaps = 8/278 (2%) Query: 10 LPPVTLAALVDSWLREDCPGLNYAALVSGAGPSQAALWAKSPGVLAGQPFFDAIFTQL-- 67 +P + LV L ED + A ++ + A + +L GQ F + + QL Sbjct: 14 VPNDIVTRLVRESLAEDIATGDITAQLAEDIDTTAFCITREEMILCGQDFANEVINQLDK 73 Query: 68 NCQVSWFLPEGSKLVPVARVAEVRGPAHCLLLGERVALNTLARCSGIASAAAAAVEAARG 127 N Q++W + K+ AR+ E++G +L ER LN + SG A+ V+ Sbjct: 74 NIQITWLYSDAQKVPANARIFELKGNVRSILTAERTILNFIQMLSGTATVTNKLVKLI-- 131 Query: 128 AGWTGHVAGTRKTTPGFRLVEKYGLLVGGAASHRYDLGGLVMVKDNHVVAAGGVEKAVRA 187 + + + TRKT PGFRL +KY + GG +HR L ++K+NH+ +AGG+ KAV Sbjct: 132 SQYKTKLLDTRKTIPGFRLAQKYAVRCGGGFNHRIGLFDAYLIKENHIRSAGGIAKAVTK 191 Query: 188 ARQAADFTLKVEVECSSLQEAVQAAEAGADLVLLDNFKPEELHPTATVLKAQFPSVAVEA 247 A++ D VEVE ++L E QA A AD+V+LDNF E++ ++ + + VA+E Sbjct: 192 AKK-LDSNKVVEVEVTNLDELNQAIAAKADIVMLDNFSGEDIDIAVSIARGK---VALEV 247 Query: 248 SGGITLDNLPQFCGPHIDVISMGMLTQAAPALDFSLKL 285 SG I +++ +D IS+G +T+ A+D SL++ Sbjct: 248 SGNIDRNSIVAIAKTGVDFISVGAITKHIKAIDLSLQV 285 >5HUL-A nrPDB Length = 314 Score = 311 bits (798), Expect = 2e-85, Method: Composition-based stats. Identities = 112/280 (40%), Positives = 154/280 (55%), Gaps = 10/280 (3%) Query: 10 LPPVTLAALVDSWLREDCPGLNYA--ALVSGAGPSQAALWAKSPGVLAGQPFFDAIFT-- 65 L P + + + LRED +Y+ A+ G ++ +L+AK GVLAG F +FT Sbjct: 33 LTPFQIDDTLKAALREDVHSEDYSTNAIFDHHGQAKVSLFAKEAGVLAGLTVFQRVFTLF 92 Query: 66 -QLNCQVSWFLPEGSKLVPVARVAEVRGPAHCLLLGERVALNTLARCSGIASAAAAAVEA 124 ++ Q +G +L V E+ G LL ERVALN L SGIAS AA VEA Sbjct: 93 DEVTFQNPHQFKDGDRLTSGDLVLEIIGSVRSLLTCERVALNFLQHLSGIASMTAAYVEA 152 Query: 125 ARGAGWTGHVAGTRKTTPGFRLVEKYGLLVGGAASHRYDLGGLVMVKDNHVVAAGGVEKA 184 V TRKTTP RL EKY + VGG +HR++L +M+KDNH+ A G V+KA Sbjct: 153 LGDDRI--KVFDTRKTTPNLRLFEKYAVRVGGGYNHRFNLSDAIMLKDNHIAAVGSVQKA 210 Query: 185 VRAARQAADFTLKVEVECSSLQEAVQAAEAGADLVLLDNFKPEELHPTATVLKAQFPSVA 244 + AR A F VEVE SL A +AA AG D+++LDN E++ T++ + Sbjct: 211 IAQARAYAPFVKMVEVEVESLAAAEEAAAAGVDIIMLDNMSLEQIEQAITLIAGRS---R 267 Query: 245 VEASGGITLDNLPQFCGPHIDVISMGMLTQAAPALDFSLK 284 +E SG I + + +F G ID +S G LT +A +LDFS+K Sbjct: 268 IECSGNIDMTTISRFRGLAIDYVSSGSLTHSAKSLDFSMK 307 >3GNN-A nrPDB Length = 298 Score = 291 bits (745), Expect = 2e-79, Method: Composition-based stats. Identities = 97/274 (35%), Positives = 144/274 (52%), Gaps = 9/274 (3%) Query: 15 LAALVDSWLREDCPGLN-YAALVSGAGPSQAALWAKSPGVLAGQPFFDAIFTQLN--CQV 71 +A V L ED + LV P +A + + VL G P+FDA+ ++ +V Sbjct: 29 IARNVADALAEDVGSGDQTGRLVPDGAPRRARVIVREDAVLCGVPWFDAVVRAVDPSIEV 88 Query: 72 SWFLPEGSKLVPVARVAEVRGPAHCLLLGERVALNTLARCSGIASAAAAAVEAARGAGWT 131 W EG ++ + V E+RGPA LL ER ALN L SG+ASA V+ R A Sbjct: 89 DWRHREGDRMSADSTVCELRGPARALLTAERNALNFLQLLSGVASATRQYVD--RIADTR 146 Query: 132 GHVAGTRKTTPGFRLVEKYGLLVGGAASHRYDLGGLVMVKDNHVVAAGGVEKAVRAARQA 191 + TRKT PG RL +KY + VGG A+ R L +++K+NH+ AAGGV +A+ AA A Sbjct: 147 ARILDTRKTLPGLRLAQKYAVRVGGGANQRLALYAGILIKENHIAAAGGVGEALDAA-FA 205 Query: 192 ADFTLKVEVECSSLQEAVQAAEAGADLVLLDNFKPEELHPTATVLKAQFPSVAVEASGGI 251 + + V++E +L + A GA VLLDNF + + V + + +E SGG+ Sbjct: 206 LNAEVPVQIEVETLDQLRTALAHGARSVLLDNFTLDMMRDAVRVTEGR---AVLEVSGGV 262 Query: 252 TLDNLPQFCGPHIDVISMGMLTQAAPALDFSLKL 285 D + +D IS+G LT+ A D+S+++ Sbjct: 263 NFDTVRAIAETGVDRISIGALTKDVRATDYSMRI 296 >1O4U-A nrPDB Length = 285 Score = 285 bits (729), Expect = 2e-77, Method: Composition-based stats. Identities = 94/272 (34%), Positives = 147/272 (54%), Gaps = 5/272 (1%) Query: 15 LAALVDSWLREDCPGLNYAALVSGAGPSQAALWAKSPGVLAGQPFFDAIFTQLNCQVSWF 74 + L+ S+++ED L+ A+ + A L K+ V+A +F + +S F Sbjct: 16 ILDLLMSFVKEDEGKLDLASFPLRNTTAGAHLLLKTENVVASGIEVSRMFLEKMGLLSKF 75 Query: 75 -LPEGSKLVPVARVAEVRGPAHCLLLGERVALNTLARCSGIASAAAAAVEAARGAGWTGH 133 + +G L + E+ G + LL+ ER LN L+ +A+ E + A Sbjct: 76 NVEDGEYLEGTGVIGEIEGNTYKLLVAERTLLNVLSVMFSVATTTRRFAEKLKHA----K 131 Query: 134 VAGTRKTTPGFRLVEKYGLLVGGAASHRYDLGGLVMVKDNHVVAAGGVEKAVRAARQAAD 193 +A TRK PG +++K ++ GG HR DL G VM+KDNH+ G E+AV+ R+ Sbjct: 132 IAATRKILPGLGVLQKIAVVHGGGDPHRLDLSGCVMIKDNHLKMYGSAERAVQEVRKIIP 191 Query: 194 FTLKVEVECSSLQEAVQAAEAGADLVLLDNFKPEELHPTATVLKAQFPSVAVEASGGITL 253 FT K+EVE +L++A++A EAGAD+V+LDN PEE+ + +K P+V VE SGGIT Sbjct: 192 FTTKIEVEVENLEDALRAVEAGADIVMLDNLSPEEVKDISRRIKDINPNVIVEVSGGITE 251 Query: 254 DNLPQFCGPHIDVISMGMLTQAAPALDFSLKL 285 +N+ + +DVIS LT +D SL++ Sbjct: 252 ENVSLYDFETVDVISSSRLTLQEVFVDLSLEI 283 >1X1O-A nrPDB Length = 286 Score = 282 bits (722), Expect = 1e-76, Method: Composition-based stats. Identities = 117/273 (42%), Positives = 158/273 (57%), Gaps = 9/273 (3%) Query: 15 LAALVDSWLREDCPGLNYAAL--VSGAGPSQAALWAKSPGVLAGQPFFDAIFTQLNCQVS 72 L + +WLRED + +L V +A + AK GVLAG + +F + + + Sbjct: 14 LEEALRAWLREDLGQGDLTSLLVVPEDLEGEAVILAKEGGVLAGLWVAERVFALADPRTA 73 Query: 73 W--FLPEGSKLVPVARVAEVRGPAHCLLLGERVALNTLARCSGIASAAAAAVEAARGAGW 130 + + EG+++ VA VRGP +L GER+ALN L R SGIA+ A VEA AG Sbjct: 74 FTPLVAEGARVAEGTEVARVRGPLRGILAGERLALNLLQRLSGIATLTRAYVEAL--AGT 131 Query: 131 TGHVAGTRKTTPGFRLVEKYGLLVGGAASHRYDLGGLVMVKDNHVVAAGGVEKAVRAARQ 190 + TRKTTPG R +EKY + VGG +HRY L +++K+NHV AAGGV +AVR A+ Sbjct: 132 KAQILDTRKTTPGLRALEKYAVRVGGGRNHRYGLFDGILLKENHVRAAGGVGEAVRRAKA 191 Query: 191 AADFTLKVEVECSSLQEAVQAAEAGADLVLLDNFKPEELHPTATVLKAQFPSVAVEASGG 250 A LKVEVE SL+E +A EAGADL+LLDNF E L + + P +EASG Sbjct: 192 RAPHYLKVEVEVRSLEELEEALEAGADLILLDNFPLEALREAVRRVGGRVP---LEASGN 248 Query: 251 ITLDNLPQFCGPHIDVISMGMLTQAAPALDFSL 283 +TL+ +D +S+G LT +A ALD SL Sbjct: 249 MTLERAKAAAEAGVDYVSVGALTHSAKALDLSL 281 >1QPQ-A nrPDB Length = 284 Score = 282 bits (721), Expect = 1e-76, Method: Composition-based stats. Identities = 88/270 (32%), Positives = 134/270 (49%), Gaps = 10/270 (3%) Query: 23 LREDC---PGLNYAALVSGAGPSQAALWAKSPGVLAGQPFF----DAIFTQLNCQVSWFL 75 L ED P + A V + + A+L + GV+AG + + +V + Sbjct: 18 LDEDLRYGPDVTTLATVPASATTTASLVTREAGVVAGLDVALLTLNEVLGTNGYRVLDRV 77 Query: 76 PEGSKLVPVARVAEVRGPAHCLLLGERVALNTLARCSGIASAAAAAVEAARGAGWTGHVA 135 +G+++ P + + LL ER LN + SGIA+A AA V+A RG + Sbjct: 78 EDGARVPPGEALMTLEAQTRGLLTAERTMLNLVGHLSGIATATAAWVDAVRGT--KAKIR 135 Query: 136 GTRKTTPGFRLVEKYGLLVGGAASHRYDLGGLVMVKDNHVVAAGGVEKAVRAARQAADFT 195 TRKT PG R ++KY + GG +HR LG ++KDNHV AAG V A+RA R AA Sbjct: 136 DTRKTLPGLRALQKYAVRTGGGVNHRLGLGDAALIKDNHVAAAGSVVDALRAVRNAAP-D 194 Query: 196 LKVEVECSSLQEAVQAAEAGADLVLLDNFKPEELHPTATVLKAQFPSVAVEASGGITLDN 255 L EVE SL++ +L+LLDNF + ++ P+V +E+SGG++L Sbjct: 195 LPCEVEVDSLEQLDAVLPEKPELILLDNFAVWQTQTAVQRRDSRAPTVMLESSGGLSLQT 254 Query: 256 LPQFCGPHIDVISMGMLTQAAPALDFSLKL 285 + +D +++G LT + LD L + Sbjct: 255 AATYAETGVDYLAVGALTHSVRVLDIGLDM 284 >3L0G-A nrPDB Length = 300 Score = 276 bits (706), Expect = 7e-75, Method: Composition-based stats. Identities = 68/274 (24%), Positives = 124/274 (45%), Gaps = 10/274 (3%) Query: 16 AALVDSWLREDCP--GLNYAALVSGAGPSQAALWAKSPGVLAGQPFFDAIFTQLNCQVSW 73 + ++ + L+ED G + A+ + V+ G P + +F V + Sbjct: 27 SEIIHNALKEDLGDKGDITTNSILINEKVNFAINTRENLVVCGIPILEEVFNMNKEHVKY 86 Query: 74 FLPEGSKLVPVARVAEVRGPAHCLLL--GERVALNTLARCSGIASAAAAAVEAARGAGWT 131 + + + V G A + L ERV LN + SGIAS V+ G Sbjct: 87 EIHKKDGDITGKNSTLVSGEALAIYLLPIERVILNFIQHASGIASITRQFVDEVSGTKV- 145 Query: 132 GHVAGTRKTTPGFRLVEKYGLLVGGAASHRYDLGGLVMVKDNHVVAAGGVEKAVRAARQA 191 + TRKTTPG R+++KY + +GG S+R +L V++KDNH+ + G + A++ R+ Sbjct: 146 -KIRSTRKTTPGLRMLDKYSVCIGGGESYRDNLCDGVLIKDNHIASCGSITLAIQRLRKN 204 Query: 192 ADFTLKVEVECSSLQEAVQAAEAGADLVLLDNFKPEELHPTATVLKAQFPSVAVEASGGI 251 + +EC ++ + ++ D++LLDN E+ ++ + +E SG + Sbjct: 205 LK-NEYIAIECDNISQVEESLSNNVDMILLDNMSISEIKKAVDIVNGKS---VLEVSGCV 260 Query: 252 TLDNLPQFCGPHIDVISMGMLTQAAPALDFSLKL 285 + N+ +D IS+G +T + D L + Sbjct: 261 NIRNVRNIALTGVDYISIGCITNSFQNKDIGLDI 294 >2I14-A nrPDB Length = 395 Score = 60.4 bits (145), Expect = 1e-09, Method: Composition-based stats. Identities = 57/287 (19%), Positives = 99/287 (34%), Gaps = 37/287 (12%) Query: 36 VSGAGPSQAALWAKSPGVLAGQPFFDAIFTQLNCQVSWFLPEGSKLVPVARVAEVRGPAH 95 V + + GVL G + + V + +PEG+ P V ++ G Sbjct: 44 VLADVTTTSLPNNWRWGVLVGVEEVAKLLEGIPVNV-YAMPEGTIFHPYEPVLQIEGDYA 102 Query: 96 CLLLGERVALNTLARCSGIASAAAAAVEAARGAGWTGHVAGTRKTTPGFRLVEKYGLLVG 155 + E L L++ SGIA+AA AA+ G R P + +G Sbjct: 103 DFGIYETALLGMLSQASGIATAALRIKIAAKFKPVYS--FGIRHMHPAIAPMIDRAAFIG 160 Query: 156 GAASHRYDLGGLVMVKDNHVVAAGGVEKAV-----RAARQAADFTLKVEVECSSLQEAVQ 210 G + G M+ + A G + A+ + F +E E + Sbjct: 161 GCDGVS-GVLGAEMMGE---KAVGTMPHALIITVGDQVKAWKYFDEVIEEEVPRIALVDT 216 Query: 211 AAEAGADLVL-------------LD-------NFK--PEELHPTATVLKAQFPSVAVEAS 248 + + V+ LD NF+ EE+ V + V + S Sbjct: 217 FYDEKVEAVMAAEALGKKLFAVRLDTPSSRRGNFRKIIEEVRWELKVRG--YDWVKIFVS 274 Query: 249 GGITLDNLPQFCGPHIDVISMGMLTQAAPALDFSLKLFAKEVAPVPK 295 GG+ + + + +D +G +A +DF+L + E P+ K Sbjct: 275 GGLDEEKIKEIVDV-VDAFGVGGAIASAKPVDFALDIVEVEGKPIAK 320 >1XI3-A nrPDB Length = 215 Score = 38.5 bits (88), Expect = 0.004, Method: Composition-based stats. Identities = 24/92 (26%), Positives = 41/92 (44%), Gaps = 8/92 (8%) Query: 185 VRAARQAADFTLKVEVECSSLQEAVQAAEAGADLVLLDNFKPEELHPTATVLKAQFPSVA 244 + A++ A L + SL+EA++A + GAD + + P + A V+ + Sbjct: 99 IEVAKEIAP-NLIIGASVYSLEEALEAEKKGADYLGAGSVFPTKTKEDARVIGLEGLRKI 157 Query: 245 VE-------ASGGITLDNLPQFCGPHIDVISM 269 VE A GGI DN + +D I++ Sbjct: 158 VESVKIPVVAIGGINKDNAREVLKTGVDGIAV 189 >1YTE-A nrPDB Length = 398 Score = 36.1 bits (82), Expect = 0.017, Method: Composition-based stats. Identities = 43/268 (16%), Positives = 87/268 (32%), Gaps = 30/268 (11%) Query: 54 LAGQPFFDAIFTQLNCQVSWFLPEGSKLVPVAR------VAEVRGPAHCLLLGERVALNT 107 G + L+ + + +PEG+ L P V G + E L Sbjct: 60 FTGLDEVLKLLEGLDVDL-YAIPEGTILFPRDANGLPVPFIRVEGRYCDFGMYETAILGF 118 Query: 108 LARCSGIASAAAAAVEAARGAGWTGHVAGTRKTTPGFRLVEKYGLLVGGAASHRYDLGGL 167 + + SGI++ A+ AA + + G R+ P + +GGA + G Sbjct: 119 ICQASGISTKASKVRLAAGDSPFFS--FGIRRMHPAISPMIDRSAYIGGADGVS-GILGA 175 Query: 168 VMVKDNHV--------VAAGGVEKAVRAARQAADFTLKVEVECSSLQEAVQAAE-----A 214 ++ + V + G E + V + + + E A + Sbjct: 176 KLIDQDPVGTMPHALSIMLGDEEAWKLTLENTKNGQKSVLLIDTYMDEKFAAIKIAEMFD 235 Query: 215 GADLVLLDNFKPEELHPTATVLKAQFPSVA-------VEASGGITLDNLPQFCGPHIDVI 267 D + LD + A + + ++ + SGG+ + + + + Sbjct: 236 KVDYIRLDTPSSRRGNFEALIREVRWELALRGRSDIKIMVSGGLDENTVKKLREAGAEAF 295 Query: 268 SMGMLTQAAPALDFSLKLFAKEVAPVPK 295 +G +A DF++ + P K Sbjct: 296 GVGTSISSAKPFDFAMDIVEVNGKPETK 323 >5UQG-A nrPDB Length = 406 Score = 35.0 bits (79), Expect = 0.038, Method: Composition-based stats. Identities = 16/74 (21%), Positives = 34/74 (45%), Gaps = 4/74 (5%) Query: 200 VECSSLQEAVQAAEAGADLVLLDNFKP--EELHPTATVLKAQFPSVAVEASGGITLDNLP 257 + + EAG D+V+LD+ + + T +KA++P++ + +G I Sbjct: 143 IGVGQMDRVDALVEAGVDVVVLDSAHGHSKGIIDTVKAIKAKYPNLDL-IAGNIATAAAA 201 Query: 258 Q-FCGPHIDVISMG 270 + C +D + +G Sbjct: 202 KALCEAGVDAVKVG 215 >1ZFJ-A nrPDB Length = 491 Score = 34.2 bits (77), Expect = 0.061, Method: Composition-based stats. Identities = 24/110 (21%), Positives = 43/110 (39%), Gaps = 6/110 (5%) Query: 164 LGGLVMVKDNHVVAAGGVEKAVRAARQAADFTLKVEVECSSLQEAVQAAEAGADLVLLDN 223 L GL+ +KD + A + V V + + A EAGAD +++D Sbjct: 196 LSGLITIKD--IEKVIEFPHAAKDEFGRLLVAAAVGVTSDTFERAEALFEAGADAIVIDT 253 Query: 224 FKPE--ELHPTATVLKAQFPSVAVEASGGI-TLDNLPQFCGPHIDVISMG 270 + ++A FP+ + +G I T + +DV+ +G Sbjct: 254 AHGHSAGVLRKIAEIRAHFPNRTL-IAGNIATAEGARALYDAGVDVVKVG 302 >3O15-A nrPDB Length = 235 Score = 33.1 bits (74), Expect = 0.16, Method: Composition-based stats. Identities = 31/123 (25%), Positives = 44/123 (35%), Gaps = 15/123 (12%) Query: 180 GVEKAVRAARQAADFTLKVEVECSSLQEAVQAAEAGADLVLLDNFKPEELH--------- 230 G E A +AA + + V ++ E QA E GAD V L P E Sbjct: 109 GQEDANAKEVRAAIGDMILGVSAHTMSEVKQAEEDGADYVGLGPIYPTETKKDTRAVQGV 168 Query: 231 ---PTATVLKAQFPSVAVEASGGITLDNLPQFCGPHIDVISMGMLTQAAPALDFSLKLFA 287 P V + GGIT+DN D +SM A + + + F Sbjct: 169 SLIEAVRRQGISIPIVGI---GGITIDNAAPVIQAGADGVSMISAISQAEDPESAARKFR 225 Query: 288 KEV 290 +E+ Sbjct: 226 EEI 228 >3T55-A nrPDB Length = 272 Score = 32.7 bits (73), Expect = 0.18, Method: Composition-based stats. Identities = 18/76 (23%), Positives = 31/76 (40%), Gaps = 5/76 (6%) Query: 200 VECSSLQEAVQAAEAGADLVLL---DNFKPEELHPTATVLKAQFPSVAVEA--SGGITLD 254 VE + QEA +A +AGA ++ + D + + PS + SG Sbjct: 167 VEVHTEQEADRALKAGAKVIGVNARDLMTLDVDRDCFARIAPGLPSSVIRIAESGVRGTA 226 Query: 255 NLPQFCGPHIDVISMG 270 +L + G D + +G Sbjct: 227 DLLAYAGAGADAVLVG 242 >4FXS-A nrPDB Length = 496 Score = 32.7 bits (73), Expect = 0.19, Method: Composition-based stats. Identities = 19/114 (16%), Positives = 39/114 (34%), Gaps = 4/114 (3%) Query: 159 SHRYDLGGLVMVKDNHVVAAGGVEKAVRAARQAADFTLKVEVECSSLQEAVQAAEAGADL 218 + + L G++ KD H A A + + V + + EAG D+ Sbjct: 189 NDEFQLKGMITAKDFH--KAESKPNACKDEQGRLRVGAAVGAAPGNEERVKALVEAGVDV 246 Query: 219 VLLDNFKPEELHPTATVLKAQFPSVAVEASGG--ITLDNLPQFCGPHIDVISMG 270 +L+D+ + + + +E GG T + + + +G Sbjct: 247 LLIDSSHGHSEGVLQRIRETRAAYPHLEIIGGNVATAEGARALIEAGVSAVKVG 300 >3OVQ-A nrPDB Length = 228 Score = 32.7 bits (73), Expect = 0.21, Method: Composition-based stats. Identities = 13/46 (28%), Positives = 23/46 (50%) Query: 226 PEELHPTATVLKAQFPSVAVEASGGITLDNLPQFCGPHIDVISMGM 271 E++ P L+ QFPS+ +E GG+ D + + ++I G Sbjct: 153 MEDMMPKVHWLRTQFPSLDIEVDGGVGPDTVHKCAEAGANMIVSGS 198 >3QE3-A nrPDB Length = 355 Score = 31.5 bits (70), Expect = 0.42, Method: Composition-based stats. Identities = 18/56 (32%), Positives = 25/56 (44%), Gaps = 1/56 (1%) Query: 195 TLKVEVECSSLQEAVQAAEAGADLVL-LDNFKPEELHPTATVLKAQFPSVAVEASG 249 +V V S +A E GAD +L + N PEE+ L P V +E +G Sbjct: 195 AAQVVVTDLSASRLSKAKEVGADFILEISNESPEEIAKKVEGLLGSKPEVTIECTG 250 >4QJ1-A nrPDB Length = 361 Score = 31.5 bits (70), Expect = 0.45, Method: Composition-based stats. Identities = 15/87 (17%), Positives = 34/87 (39%), Gaps = 1/87 (1%) Query: 185 VRAARQAADFTLKVEVECSSLQEAVQAAEAGADLVLLDNFKPEELHPTATVLKAQFPSVA 244 V + + + + + ++ A EAG D+++LD+ L+ T+ + + Sbjct: 87 VLKVKNSGGLRVGAAIGVNEIERAKLLVEAGVDVIVLDSAHGHSLNIIRTLKEIKSKMNI 146 Query: 245 VEASGG-ITLDNLPQFCGPHIDVISMG 270 G +T + + D I +G Sbjct: 147 DVIVGNVVTEEATKELIENGADGIKVG 173 >3F4W-A nrPDB Length = 211 Score = 31.1 bits (69), Expect = 0.54, Method: Composition-based stats. Identities = 23/104 (22%), Positives = 47/104 (45%), Gaps = 9/104 (8%) Query: 181 VEKAVRAARQAADFTLKVEVECSSLQEAVQAAE-AGADLVLLDNFKPEE------LHPTA 233 ++ +RAA++A + + L V+ E AGAD++ + ++ + Sbjct: 92 IQSCIRAAKEAGKQVVVDMICVDDLPARVRLLEEAGADMLAVHTGTDQQAAGRKPIDDLI 151 Query: 234 TVLKAQFPSVAVEASGGITLDNLPQFCGPHIDVISMG-MLTQAA 276 T+LK + + +GGI+ + + DV+ +G +T AA Sbjct: 152 TMLKVRRK-ARIAVAGGISSQTVKDYALLGPDVVIVGSAITHAA 194 >6I0M-A nrPDB Length = 517 Score = 31.1 bits (69), Expect = 0.58, Method: Composition-based stats. Identities = 16/90 (17%), Positives = 35/90 (38%), Gaps = 2/90 (2%) Query: 184 AVRAARQAADFTLKVEVECSSLQEAVQAAEAGADLVLLDNFKPEELHPT--ATVLKAQFP 241 A + A++ + A+AG D+V+LD+ + + +K ++P Sbjct: 239 ASKDAKKQLLCGAAIGTHEDDKYRLDLLAQAGVDVVVLDSSQGNSIFQINMIKYIKDKYP 298 Query: 242 SVAVEASGGITLDNLPQFCGPHIDVISMGM 271 ++ V +T +D + +GM Sbjct: 299 NLQVIGGNVVTAAQAKNLIDAGVDALRVGM 328 >3FFS-A nrPDB Length = 400 Score = 31.1 bits (69), Expect = 0.59, Method: Composition-based stats. Identities = 14/72 (19%), Positives = 30/72 (41%), Gaps = 1/72 (1%) Query: 200 VECSSLQEAVQAAEAGADLVLLDNFKPEELHPTATVLKAQFPSVAVEASGG-ITLDNLPQ 258 + + ++ A EAG D+++LD+ L+ T+ + + G +T + + Sbjct: 141 IGVNEIERAKLLVEAGVDVIVLDSAHGHSLNIIRTLKEIKSKMNIDVIVGNVVTEEATKE 200 Query: 259 FCGPHIDVISMG 270 D I +G Sbjct: 201 LIENGADGIKVG 212 >1VRD-A nrPDB Length = 494 Score = 30.7 bits (68), Expect = 0.68, Method: Composition-based stats. Identities = 21/110 (19%), Positives = 45/110 (40%), Gaps = 6/110 (5%) Query: 164 LGGLVMVKDNHVVAAGGVEKAVRAARQAADFTLKVEVECSSLQEAVQAAEAGADLVLLDN 223 L GL+ +KD +++ A R + V +++ + +AG D++++D Sbjct: 200 LVGLITIKD--IMSVIEHPNAARDEKGRLLVGAAVGTSPETMERVEKLVKAGVDVIVIDT 257 Query: 224 FKPEELH--PTATVLKAQFPSVAVEASGGI-TLDNLPQFCGPHIDVISMG 270 T ++KA +P + V +G + T + D + +G Sbjct: 258 AHGHSRRVIETLEMIKADYPDLPV-VAGNVATPEGTEALIKAGADAVKVG 306 >4FEZ-A nrPDB Length = 388 Score = 30.4 bits (67), Expect = 1.1, Method: Composition-based stats. Identities = 11/69 (15%), Positives = 25/69 (36%), Gaps = 2/69 (2%) Query: 204 SLQEAVQAAEAGADLVLLDNFKPEELHPTATVLKAQFPSVAVEASGG--ITLDNLPQFCG 261 + + EAG D++L+D+ + + + +E GG T + Sbjct: 131 NEERVKALVEAGVDVLLIDSSHGHSEGVLQRIRETRAAYPHLEIIGGNVATAEGARALIE 190 Query: 262 PHIDVISMG 270 + + +G Sbjct: 191 AGVSAVKVG 199 >2F7F-A nrPDB Length = 494 Score = 29.6 bits (65), Expect = 1.6, Method: Composition-based stats. Identities = 34/166 (20%), Positives = 51/166 (30%), Gaps = 34/166 (20%) Query: 77 EGSKLVPVARVAEVRGPAHCLLLGERVALNTLARCSGIASAAAAAVEAA----------- 125 EG + + ++ GP L E LN + + IA+ AA Sbjct: 104 EGDLVFNNEPLIQIEGPLAQCQLVETALLNMVNFQTLIATKAARIKSVIGDDPLLEFGTR 163 Query: 126 RGAGWTGHVAGTR-------KTTPGFRLVEKYGLLVGGAASHRYDLG------------- 165 R + GTR T R + +G+ V G +H Sbjct: 164 RAQELDAAIWGTRAAYIGGADATSNVRAGKIFGIPVSGTHAHSLVQSYGNDYEAFMAYAK 223 Query: 166 ---GLVMVKDNHVVAAGGVEKAVRAARQAADFTLKVEVECSSLQEA 208 V + D + GV A+R AR+ D + V S A Sbjct: 224 THRDCVFLVDTYDTLKAGVPSAIRVAREMGDKINFLGVRIDSGDMA 269 >4DZA-A nrPDB Length = 407 Score = 29.6 bits (65), Expect = 1.8, Method: Composition-based stats. Identities = 23/116 (19%), Positives = 43/116 (37%), Gaps = 2/116 (1%) Query: 151 GLLVGGAASHRYDLGGLVMVKDNHVVAAG-GVEKAVRAARQAADFTLKVEVECSSLQEAV 209 +L G A H L +M+ +N+V G + ++ R + V ++ QE Sbjct: 71 AVLKGDAYGHDLSLVAPIMI-ENNVKCIGVTNNQELKEVRDLGFKGRLMRVRNATEQEMA 129 Query: 210 QAAEAGADLVLLDNFKPEELHPTATVLKAQFPSVAVEASGGITLDNLPQFCGPHID 265 QA + ++ D + L A P SGG++ + L ++ Sbjct: 130 QATNYNVEELIGDLDMAKRLDAIAKQQNKVIPIHLALNSGGMSRNGLEVDNKSGLE 185 >6HUL-A nrPDB Length = 241 Score = 29.2 bits (64), Expect = 2.3, Method: Composition-based stats. Identities = 13/51 (25%), Positives = 21/51 (41%) Query: 180 GVEKAVRAARQAADFTLKVEVECSSLQEAVQAAEAGADLVLLDNFKPEELH 230 V++ + R + L V SS + A AGAD + + EE+ Sbjct: 170 SVKQLINRVRNLVENKLIVGFGLSSESDLRDALSAGADGIAIGTVFIEEIE 220 >1JCN-A nrPDB Length = 514 Score = 28.8 bits (63), Expect = 3.2, Method: Composition-based stats. Identities = 13/61 (21%), Positives = 28/61 (45%), Gaps = 2/61 (3%) Query: 213 EAGADLVLLDNFKPEELHPTATVLKAQFPSVAVEASGG--ITLDNLPQFCGPHIDVISMG 270 +AG D+++LD+ + ++ A V + ++ GG +T +D + +G Sbjct: 265 QAGVDVIVLDSSQGNSVYQIAMVHYIKQKYPHLQVIGGNVVTAAQAKNLIDAGVDGLRVG 324 Query: 271 M 271 M Sbjct: 325 M 325 >2JFH-A nrPDB Length = 445 Score = 28.4 bits (62), Expect = 4.0, Method: Composition-based stats. Identities = 29/132 (21%), Positives = 47/132 (35%), Gaps = 11/132 (8%) Query: 122 VEAARGAGWTGHVAGTRKTTPGFRLVEKYGLLVGGAASHRYDLGGLVMVKDNHVVAAGGV 181 V+ G T V TR T PG + + G L ++ + +VA+ G+ Sbjct: 22 VDFFLARGVTPRVMDTRMTPPGLDKLPEAVERHTG------SLNDEWLMAADLIVASPGI 75 Query: 182 EKAVRAARQAADFTLKVEVECSSLQEAVQAAEAGADLVLLDNFKPEELHPTATVLKAQFP 241 A + AAD +++ + EA A +V + + T A+ Sbjct: 76 ALAHPSLSAAADAGIEIVGDIELFCR-----EAQAPIVAITGSNGKSTVTTLVGEMAKAA 130 Query: 242 SVAVEASGGITL 253 V V G I L Sbjct: 131 GVNVGVGGNIGL 142 >4LPS-A nrPDB Length = 242 Score = 28.4 bits (62), Expect = 4.1, Method: Composition-based stats. Identities = 11/52 (21%), Positives = 23/52 (44%) Query: 208 AVQAAEAGADLVLLDNFKPEELHPTATVLKAQFPSVAVEASGGITLDNLPQF 259 A + AD+V + NF+ ++ LK + P + + +L++ F Sbjct: 176 ADAVIISKADMVEVFNFRVSQVKEDMQKLKPEAPIFLMSSKDPKSLEDFKNF 227 >5UMF-A nrPDB Length = 235 Score = 28.1 bits (61), Expect = 4.6, Method: Composition-based stats. Identities = 10/48 (20%), Positives = 17/48 (35%), Gaps = 1/48 (2%) Query: 225 KPEELHPTATVLKAQFPS-VAVEASGGITLDNLPQFCGPHIDVISMGM 271 K ++ + + +A+E GGI DN+ D G Sbjct: 164 KIRQVRAMLDRYEGKSGRRIAIEVDGGIKTDNIAAVARAGADTFVAGS 211 >1V77-A nrPDB Length = 212 Score = 28.1 bits (61), Expect = 4.6, Method: Composition-based stats. Identities = 20/82 (24%), Positives = 32/82 (39%), Gaps = 7/82 (8%) Query: 199 EVECSSLQEAVQAAEAGADLVLLDNFKPEELHPTATVLKAQFPSVAVEASGGITLDNLPQ 258 EV+ L+EA + E G +LL N KP + T +F S + L + Sbjct: 39 EVDKEKLREARK--EYGKVAILLSNPKPSLVRDTVQ----KFKSYLIYVESN-DLRVIRY 91 Query: 259 FCGPHIDVISMGMLTQAAPALD 280 +D I + + P +D Sbjct: 92 SIEKGVDAIISPWVNRKDPGID 113 >6BMA-A nrPDB Length = 261 Score = 28.1 bits (61), Expect = 5.4, Method: Composition-based stats. Identities = 15/96 (15%), Positives = 39/96 (40%), Gaps = 9/96 (9%) Query: 184 AVRAARQAADFTLKVE----VECSSLQEAVQAAEAGADLVLLDNFKPEELHPTATVLKAQ 239 +++ ++ +F + VE ++ +A AGAD++ +++ E+ ++ + Sbjct: 149 SMKELKKLLEFARHLGLEALVEIHDKEDLSKAIFAGADIIGINHRNLEDFTMDMSLCEKL 208 Query: 240 FPS-----VAVEASGGITLDNLPQFCGPHIDVISMG 270 P + + SG + L +D +G Sbjct: 209 IPQIPNSKIIIAESGLENKEFLEHLQNLGVDAFLIG 244 >1H1Z-A nrPDB Length = 228 Score = 27.7 bits (60), Expect = 6.1, Method: Composition-based stats. Identities = 11/48 (22%), Positives = 20/48 (41%), Gaps = 1/48 (2%) Query: 224 FKPEELHPTATVLKAQFPSVAVEASGGITLDNLPQFCGPHIDVISMGM 271 F PE + L+ ++PS+ +E GG+ + + I G Sbjct: 156 FMPEMMEK-VRALRKKYPSLDIEVDGGLGPSTIDVAASAGANCIVAGS 202 >3INP-A nrPDB Length = 246 Score = 27.7 bits (60), Expect = 6.2, Method: Composition-based stats. Identities = 5/46 (10%), Positives = 17/46 (36%) Query: 226 PEELHPTATVLKAQFPSVAVEASGGITLDNLPQFCGPHIDVISMGM 271 ++ + + + + +E GG+ N+ + ++ G Sbjct: 179 LDKAKEISKWISSTDRDILLEIDGGVNPYNIAEIAVCGVNAFVAGS 224 >4YUB-A nrPDB Length = 538 Score = 27.7 bits (60), Expect = 7.2, Method: Composition-based stats. Identities = 16/47 (34%), Positives = 23/47 (48%) Query: 75 LPEGSKLVPVARVAEVRGPAHCLLLGERVALNTLARCSGIASAAAAA 121 LPEGS P + +V GP + L E L ++ S +A+ AA Sbjct: 109 LPEGSLAFPGVPLLQVSGPLLVVQLLETPLLCLVSYASLVATNAARL 155 >2I71-A nrPDB Length = 400 Score = 27.3 bits (59), Expect = 7.5, Method: Composition-based stats. Identities = 6/33 (18%), Positives = 15/33 (45%) Query: 248 SGGITLDNLPQFCGPHIDVISMGMLTQAAPALD 280 SG + LD L + + D ++ ++ ++ Sbjct: 304 SGNVDLDTLRHYAETYADKVTRAIIENEVDKIE 336 >3Q94-A nrPDB Length = 288 Score = 27.3 bits (59), Expect = 7.7, Method: Composition-based stats. Identities = 17/82 (20%), Positives = 30/82 (36%), Gaps = 9/82 (10%) Query: 174 HVVAAGGVEKAVRAARQAADFTLKVEVECS---SLQEAVQAAEAGADLVLLD------NF 224 H+ V V+A + + T+ V + S ++ +A +AG V++D Sbjct: 59 HMTGFKTVVAMVKALIEEMNITVPVAIHLDHGSSFEKCKEAIDAGFTSVMIDASHHPFEE 118 Query: 225 KPEELHPTATVLKAQFPSVAVE 246 E A+ SV E Sbjct: 119 NVETTKKVVEYAHARNVSVEAE 140 >6MWQ-A nrPDB Length = 493 Score = 27.3 bits (59), Expect = 8.3, Method: Composition-based stats. Identities = 12/51 (23%), Positives = 18/51 (35%) Query: 206 QEAVQAAEAGADLVLLDNFKPEELHPTATVLKAQFPSVAVEASGGITLDNL 256 E GAD+ LD F LH A + V ++ + +L Sbjct: 19 DEVRILMANGADVNALDRFGLTPLHLAAQRGHLEIVEVLLKCGADVNAADL 69 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.316 0.139 0.363 Lambda K H 0.267 0.0420 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 10,858,395 Number of Sequences: 36641 Number of extensions: 398367 Number of successful extensions: 1503 Number of sequences better than 10.0: 56 Number of HSP's better than 10.0 without gapping: 48 Number of HSP's successfully gapped in prelim test: 41 Number of HSP's that attempted gapping in prelim test: 1376 Number of HSP's gapped (non-prelim): 98 length of query: 297 length of database: 10,336,785 effective HSP length: 96 effective length of query: 201 effective length of database: 6,819,249 effective search space: 1370669049 effective search space used: 1370669049 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 59 (27.3 bits)