BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q15118 (436 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 2Q8F-A nrPDB 850 0.0 3CRK-A nrPDB 599 e-172 1Y8N-A nrPDB 587 e-168 2E0A-A nrPDB 577 e-165 4DZY-A nrPDB 161 4e-40 3SL2-A nrPDB 49 3e-06 6AZR-A nrPDB 41 0.001 4U7O-A nrPDB 40 0.002 4I5S-A nrPDB 39 0.005 3D36-A nrPDB 33 0.21 4PU9-A nrPDB 32 0.66 5MMP-A nrPDB 32 0.80 5CPH-A nrPDB 31 1.3 4RLP-A nrPDB 30 1.8 4URM-A nrPDB 30 1.9 4URL-A nrPDB 30 2.9 4URN-A nrPDB 30 2.9 4L42-A nrPDB 29 3.3 2IE7-A nrPDB 29 4.5 1XRE-A nrPDB 29 4.6 4R7O-A nrPDB 29 5.0 4HZ5-A nrPDB 28 9.4 >2Q8F-A nrPDB Length = 407 Score = 850 bits (2196), Expect = 0.0, Method: Compositional matrix adjust. Identities = 407/407 (100%), Positives = 407/407 (100%) Query: 30 SDSGSSPASERGVPGQVDFYARFSPSPLSMKQFLDFGSVNACEKTSFMFLRQELPVRLAN 89 SDSGSSPASERGVPGQVDFYARFSPSPLSMKQFLDFGSVNACEKTSFMFLRQELPVRLAN Sbjct: 1 SDSGSSPASERGVPGQVDFYARFSPSPLSMKQFLDFGSVNACEKTSFMFLRQELPVRLAN 60 Query: 90 IMKEISLLPDNLLRTPSVQLVQSWYIQSLQELLDFKDKSAEDAKAIYDFTDTVIRIRNRH 149 IMKEISLLPDNLLRTPSVQLVQSWYIQSLQELLDFKDKSAEDAKAIYDFTDTVIRIRNRH Sbjct: 61 IMKEISLLPDNLLRTPSVQLVQSWYIQSLQELLDFKDKSAEDAKAIYDFTDTVIRIRNRH 120 Query: 150 NDVIPTMAQGVIEYKESFGVDPVTSQNVQYFLDRFYMSRISIRMLLNQHSLLFGGKGKGS 209 NDVIPTMAQGVIEYKESFGVDPVTSQNVQYFLDRFYMSRISIRMLLNQHSLLFGGKGKGS Sbjct: 121 NDVIPTMAQGVIEYKESFGVDPVTSQNVQYFLDRFYMSRISIRMLLNQHSLLFGGKGKGS 180 Query: 210 PSHRKHIGSINPNCNVLEVIKDGYENARRLCDLYYINSPELELEELNAKSPGQPIQVVYV 269 PSHRKHIGSINPNCNVLEVIKDGYENARRLCDLYYINSPELELEELNAKSPGQPIQVVYV Sbjct: 181 PSHRKHIGSINPNCNVLEVIKDGYENARRLCDLYYINSPELELEELNAKSPGQPIQVVYV 240 Query: 270 PSHLYHMVFELFKNAMRATMEHHANRGVYPPIQVHVTLGNEDLTVKMSDRGGGVPLRKID 329 PSHLYHMVFELFKNAMRATMEHHANRGVYPPIQVHVTLGNEDLTVKMSDRGGGVPLRKID Sbjct: 241 PSHLYHMVFELFKNAMRATMEHHANRGVYPPIQVHVTLGNEDLTVKMSDRGGGVPLRKID 300 Query: 330 RLFNYMYSTAPRPRVETSRAVPLAGFGYGLPISRLYAQYFQGDLKLYSLEGYGTDAVIYI 389 RLFNYMYSTAPRPRVETSRAVPLAGFGYGLPISRLYAQYFQGDLKLYSLEGYGTDAVIYI Sbjct: 301 RLFNYMYSTAPRPRVETSRAVPLAGFGYGLPISRLYAQYFQGDLKLYSLEGYGTDAVIYI 360 Query: 390 KALSTDSIERLPVYNKAAWKHYNTNHEADDWCVPSREPKDMTTFRSA 436 KALSTDSIERLPVYNKAAWKHYNTNHEADDWCVPSREPKDMTTFRSA Sbjct: 361 KALSTDSIERLPVYNKAAWKHYNTNHEADDWCVPSREPKDMTTFRSA 407 >3CRK-A nrPDB Length = 407 Score = 599 bits (1544), Expect = e-172, Method: Compositional matrix adjust. Identities = 274/398 (68%), Positives = 339/398 (85%), Gaps = 3/398 (0%) Query: 37 ASERGVPGQVDFYARFSPSPLSMKQFLDFGSVNACEKTSFMFLRQELPVRLANIMKEISL 96 AS G P ++ +++FSPSPLSMKQFLDFGS NACEKTSF FLRQELPVRLANIMKEI+L Sbjct: 11 ASLAGAPKYIEHFSKFSPSPLSMKQFLDFGSSNACEKTSFTFLRQELPVRLANIMKEINL 70 Query: 97 LPDNLLRTPSVQLVQSWYIQSLQELLDFKDKSAEDAKAIYDFTDTVIRIRNRHNDVIPTM 156 LPD +L TPSVQLVQSWY+QSL ++++F DK ED + + FTD ++ IRNRHNDV+PTM Sbjct: 71 LPDRVLSTPSVQLVQSWYVQSLLDIMEFLDKDPEDHRTLSQFTDALVTIRNRHNDVVPTM 130 Query: 157 AQGVIEYKESFGVDPVTSQNVQYFLDRFYMSRISIRMLLNQHSLLFGGKGKGSPSHRKHI 216 AQGV+EYK+++G DPV++QN+QYFLDRFY+SRISIRML+NQH+L+F G +P+H KHI Sbjct: 131 AQGVLEYKDTYGDDPVSNQNIQYFLDRFYLSRISIRMLINQHTLIF--DGSTNPAHPKHI 188 Query: 217 GSINPNCNVLEVIKDGYENARRLCDLYYINSPELELEELNAKSPGQPIQVVYVPSHLYHM 276 GSI+PNC+V +V+KD Y+ A+ LCD YY+ SP+LE++E+NA + QPI +VYVPSHLYHM Sbjct: 189 GSIDPNCSVSDVVKDAYDMAKLLCDKYYMASPDLEIQEVNATNATQPIHMVYVPSHLYHM 248 Query: 277 VFELFKNAMRATMEHHANRGVYPPIQVHVTLGNEDLTVKMSDRGGGVPLRKIDRLFNYMY 336 +FELFKNAMRAT+E H + PPI++ V LG EDL++KMSDRGGGVPLRKI+RLF+YMY Sbjct: 249 LFELFKNAMRATVESHESSLTLPPIKIMVALGEEDLSIKMSDRGGGVPLRKIERLFSYMY 308 Query: 337 STAPRPRVETSRAVPLAGFGYGLPISRLYAQYFQGDLKLYSLEGYGTDAVIYIKALSTDS 396 STAP P+ T PLAGFGYGLPISRLYA+YFQGDL+L+S+EG+GTDAVIY+KALSTDS Sbjct: 309 STAPTPQPGTG-GTPLAGFGYGLPISRLYAKYFQGDLQLFSMEGFGTDAVIYLKALSTDS 367 Query: 397 IERLPVYNKAAWKHYNTNHEADDWCVPSREPKDMTTFR 434 +ERLPVYNK+AW+HY T EA DWCVPS EPK+ +T+R Sbjct: 368 VERLPVYNKSAWRHYQTIQEAGDWCVPSTEPKNTSTYR 405 >1Y8N-A nrPDB Length = 419 Score = 587 bits (1513), Expect = e-168, Method: Compositional matrix adjust. Identities = 271/395 (68%), Positives = 333/395 (84%), Gaps = 3/395 (0%) Query: 42 VPGQVDFYARFSPSPLSMKQFLDFGSVNACEKTSFMFLRQELPVRLANIMKEISLLPDNL 101 VP Q++ Y+RFSPSPLS+KQFLDFG NACEKTS+MFLR+ELPVRLAN M+E++LLPDNL Sbjct: 25 VPKQIERYSRFSPSPLSIKQFLDFGRDNACEKTSYMFLRKELPVRLANTMREVNLLPDNL 84 Query: 102 LRTPSVQLVQSWYIQSLQELLDFKDKSAEDAKAIYDFTDTVIRIRNRHNDVIPTMAQGVI 161 L PSV LVQSWY+QS ELL++++KS ED + + +F +I++RNRHNDV+PTMAQGVI Sbjct: 85 LNRPSVGLVQSWYMQSFLELLEYENKSPEDPQVLDNFLQVLIKVRNRHNDVVPTMAQGVI 144 Query: 162 EYKESFGVDPVTSQNVQYFLDRFYMSRISIRMLLNQHSLLFGGKGKGSPSHRKHIGSINP 221 EYKE FG DP S N+QYFLDRFY +RIS RML+NQH+LLFG G +P H KHIGSI+P Sbjct: 145 EYKEKFGFDPFISTNIQYFLDRFYTNRISFRMLINQHTLLFG--GDTNPVHPKHIGSIDP 202 Query: 222 NCNVLEVIKDGYENARRLCDLYYINSPELELEELNAKSPGQPIQVVYVPSHLYHMVFELF 281 CNV +V+KD YE A+ LC+ YY+ +PELE+EE NAK+P +PIQVVYVPSHL+HM+FELF Sbjct: 203 TCNVADVVKDAYETAKMLCEQYYLVAPELEVEEFNAKAPDKPIQVVYVPSHLFHMLFELF 262 Query: 282 KNAMRATMEHHANRGV-YPPIQVHVTLGNEDLTVKMSDRGGGVPLRKIDRLFNYMYSTAP 340 KN+MRAT+E + +R YP ++ VTLG EDL++K+SD GGGVPLRKIDRLFNYMYSTAP Sbjct: 263 KNSMRATVELYEDRKEGYPAVKTLVTLGKEDLSIKISDLGGGVPLRKIDRLFNYMYSTAP 322 Query: 341 RPRVETSRAVPLAGFGYGLPISRLYAQYFQGDLKLYSLEGYGTDAVIYIKALSTDSIERL 400 RP +E +RA PLAGFGYGLPISRLYA+YFQGDLKLYS+EG GTDAVIY+KALS++S ERL Sbjct: 323 RPSLEPTRAAPLAGFGYGLPISRLYARYFQGDLKLYSMEGVGTDAVIYLKALSSESFERL 382 Query: 401 PVYNKAAWKHYNTNHEADDWCVPSREPKDMTTFRS 435 PV+NK+AW+HY T EADDW PS EP+D + +++ Sbjct: 383 PVFNKSAWRHYKTTPEADDWSNPSSEPRDASKYKA 417 >2E0A-A nrPDB Length = 394 Score = 577 bits (1487), Expect = e-165, Method: Compositional matrix adjust. Identities = 263/389 (67%), Positives = 330/389 (84%), Gaps = 3/389 (0%) Query: 42 VPGQVDFYARFSPSPLSMKQFLDFGSVNACEKTSFMFLRQELPVRLANIMKEISLLPDNL 101 VP +V+ ++R+SPSPLSMKQ LDFGS NACE+TSF FLRQELPVRLANI+KEI +LP L Sbjct: 3 VPREVEHFSRYSPSPLSMKQLLDFGSENACERTSFAFLRQELPVRLANILKEIDILPTQL 62 Query: 102 LRTPSVQLVQSWYIQSLQELLDFKDKSAEDAKAIYDFTDTVIRIRNRHNDVIPTMAQGVI 161 + T SVQLV+SWYIQSL +L++F +KS +D KA+ DF DT+I++RNRH++V+PTMAQG+I Sbjct: 63 VNTSSVQLVKSWYIQSLMDLVEFHEKSPDDQKALSDFVDTLIKVRNRHHNVVPTMAQGII 122 Query: 162 EYKESFGVDPVTSQNVQYFLDRFYMSRISIRMLLNQHSLLFGGKGKGSPSHRKHIGSINP 221 EYK++ VDPVT+QN+QYFLDRFYM+RIS RML+NQH L+F G+PSH IGSI+P Sbjct: 123 EYKDACTVDPVTNQNLQYFLDRFYMNRISTRMLMNQHILIFSDSQTGNPSH---IGSIDP 179 Query: 222 NCNVLEVIKDGYENARRLCDLYYINSPELELEELNAKSPGQPIQVVYVPSHLYHMVFELF 281 NC+V+ V++D +E +R LCD YY++SPEL+L ++N K P QPI +VYVPSHL+HM+FELF Sbjct: 180 NCDVVAVVQDAFECSRMLCDQYYLSSPELKLTQVNGKFPDQPIHIVYVPSHLHHMLFELF 239 Query: 282 KNAMRATMEHHANRGVYPPIQVHVTLGNEDLTVKMSDRGGGVPLRKIDRLFNYMYSTAPR 341 KNAMRAT+EH N+ PI+V V LG EDLT+K+SDRGGGVPLR IDRLF+Y YSTAP Sbjct: 240 KNAMRATVEHQENQPSLTPIEVIVVLGKEDLTIKISDRGGGVPLRIIDRLFSYTYSTAPT 299 Query: 342 PRVETSRAVPLAGFGYGLPISRLYAQYFQGDLKLYSLEGYGTDAVIYIKALSTDSIERLP 401 P ++ SR PLAGFGYGLPISRLYA+YFQGDL LYSL GYGTDA+IY+KALS++SIE+LP Sbjct: 300 PVMDNSRNAPLAGFGYGLPISRLYAKYFQGDLNLYSLSGYGTDAIIYLKALSSESIEKLP 359 Query: 402 VYNKAAWKHYNTNHEADDWCVPSREPKDM 430 V+NK+A+KHY + EADDWC+PSREPK++ Sbjct: 360 VFNKSAFKHYQMSSEADDWCIPSREPKNL 388 >4DZY-A nrPDB Length = 418 Score = 161 bits (408), Expect = 4e-40, Method: Compositional matrix adjust. Identities = 113/341 (33%), Positives = 182/341 (53%), Gaps = 46/341 (13%) Query: 78 FLRQELPVRLANIMKEISLLPDNLLRTPSVQLVQSWYIQSLQELLDF---KDKSAEDAKA 134 +L+QELPVR+A+ +K LP + P++ V YI++ Q+L DF KD++ E Sbjct: 93 YLQQELPVRIAHRIKGFRSLPFIIGCNPTILHVHELYIRAFQKLTDFPPIKDQADE---- 148 Query: 135 IYDFTDTVIRIRNRHNDVIPTMAQGVIEYKESFGVDPVTSQNVQYFLDRFYMSRISIRML 194 + V ++ + H DV+ +A+G+ E ++ + + V+YFLD+ SR+ IRML Sbjct: 149 -AQYCQLVRQLLDDHKDVVTLLAEGLRESRKHIEDEKL----VRYFLDKTLTSRLGIRML 203 Query: 195 LNQHSLLFGGKGKGSPSHRKHIGSINPNCNVLEVIKDGYENARRLCDLYYINSPELELE- 253 H L K +G I + ++I+ + ARRLC+ Y N+P + + Sbjct: 204 ATHHLALHEDKPD-------FVGIICTRLSPKKIIEKWVDFARRLCEHKYGNAPRVRING 256 Query: 254 ELNAKSPGQPIQVVYVPSHLYHMVFELFKNAMRATMEHHANRGVYPPIQVHVTLGNED-- 311 + A+ P ++P L +++ EL KNAMRATME H + P V +T+ N D Sbjct: 257 HVAARFP-------FIPMPLDYILPELLKNAMRATMESHLDTPYNVP-DVVITIANNDVD 308 Query: 312 LTVKMSDRGGGVPLRKIDRLFNYMYSTAPR----PRVE----------TSRAVPLAGFGY 357 L +++SDRGGG+ + +DR+ +Y ++TA PR+ ++ P+ GFG+ Sbjct: 309 LIIRISDRGGGIAHKDLDRVMDYHFTTAEASTQDPRISPLFGHLDMHSGGQSGPMHGFGF 368 Query: 358 GLPISRLYAQYFQGDLKLYSLEGYGTDAVIYIKALSTDSIE 398 GLP SR YA+Y G L+L SL+G GTD +Y++ D E Sbjct: 369 GLPTSRAYAEYLGGSLQLQSLQGIGTD--VYLRLRHIDGRE 407 >3SL2-A nrPDB Length = 177 Score = 49.3 bits (116), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 31/92 (33%), Positives = 47/92 (51%), Gaps = 12/92 (13%) Query: 298 YPPIQVHVTLG---NED---LTVKMSDRGGGVPLRKIDRLFNYMYSTAPRPRVETSRAVP 351 Y P HVT NE+ L + + D G G+P + ++++F+ Y RV+ +R Sbjct: 58 YSPEGGHVTFSIDVNEEEELLYISVKDEGIGIPKKDVEKVFDRFY------RVDKARTRK 111 Query: 352 LAGFGYGLPISRLYAQYFQGDLKLYSLEGYGT 383 L G G GL I++ Q GD+ S+EG GT Sbjct: 112 LGGTGLGLAIAKEMVQAHGGDIWADSIEGKGT 143 >6AZR-A nrPDB Length = 259 Score = 40.8 bits (94), Expect = 0.001, Method: Compositional matrix adjust. Identities = 30/129 (23%), Positives = 57/129 (44%), Gaps = 14/129 (10%) Query: 263 PIQVVYVPSHLYHMVFELFKNAMRATMEHHANRGVYPPIQVHVTLGNED--LTVKMSDRG 320 P++ P+ + ++ L N ++ + + P V V L +D + + + D G Sbjct: 130 PVEAYIDPTRIRQVLLNLLNNGVKYSKKD------APDKYVKVILDEKDGGVLIIVEDNG 183 Query: 321 GGVPLRKIDRLFNYMYSTAPRPRVETSRAVPLAGFGYGLPISRLYAQYFQGDLKLYSLEG 380 G+P DR+F Y RV++S + G G GL I++ + G + + S G Sbjct: 184 IGIPDHAKDRIFEQFY------RVDSSLTYEVPGTGLGLAITKEIVELHGGRIWVESEVG 237 Query: 381 YGTDAVIYI 389 G+ ++I Sbjct: 238 KGSRFFVWI 246 >4U7O-A nrPDB Length = 277 Score = 40.4 bits (93), Expect = 0.002, Method: Compositional matrix adjust. Identities = 25/105 (23%), Positives = 51/105 (48%), Gaps = 9/105 (8%) Query: 279 ELFKNAMRATMEHHANRGVYPPIQVHVTLGNEDLTVKMSDRGGGVPLRKIDRLFNYMYST 338 ++ N M +++ + GV + + + + + +SD+G G+P + +F+ + Sbjct: 159 QVLDNIMNNAIKYSPDGGV---VTCRLLETHNQVIISISDQGLGIPRADLGHVFDRFF-- 213 Query: 339 APRPRVETSRAVPLAGFGYGLPISRLYAQYFQGDLKLYSLEGYGT 383 RV+ +R+ G G GL IS+ Q G + + S+EG G+ Sbjct: 214 ----RVDKARSRAQGGTGLGLAISKEVVQMLGGRIWVDSVEGKGS 254 >4I5S-A nrPDB Length = 450 Score = 38.5 bits (88), Expect = 0.005, Method: Compositional matrix adjust. Identities = 30/117 (25%), Positives = 57/117 (48%), Gaps = 11/117 (9%) Query: 278 FELFKNAMRATMEHHANRGV-YPPI--QVHVTLGNED--LTVKMSDRGGGVPLRKIDRLF 332 E+ + M +++ N + Y P +V +T+ D L + +SD+G G+P + + +F Sbjct: 321 IEIDTDKMTQVIDNILNNAIKYSPDGGKVTITMQTTDTQLILSISDQGLGIPKKDLPLIF 380 Query: 333 NYMYSTAPRPRVETSRAVPLAGFGYGLPISRLYAQYFQGDLKLYSLEGYGTDAVIYI 389 + Y RV+ +R+ G G GL I++ + +G + S EG G+ I + Sbjct: 381 DRFY------RVDKARSRAQGGTGLGLAIAKEIVKQHKGFIWANSEEGEGSTFTIVL 431 >3D36-A nrPDB Length = 244 Score = 33.5 bits (75), Expect = 0.21, Method: Compositional matrix adjust. Identities = 24/107 (22%), Positives = 49/107 (45%), Gaps = 14/107 (13%) Query: 283 NAMRATMEHHANRGVYPPIQVHVTLGNEDLTVKMSDRGGGVPLRKIDRLFNYMYSTAPRP 342 N M+ +E N G +QV+V++ N + ++++D G G+ +++RL ++T Sbjct: 130 NVMKNAIEAMPNGGT---LQVYVSIDNGRVLIRIADTGVGMTKEQLERLGEPYFTTK--- 183 Query: 343 RVETSRAVPLAGFGYGLPISRLYAQYFQGDLKLYSLEGYGTDAVIYI 389 + G G G+ + + G +++ S GT IY+ Sbjct: 184 --------GVKGTGLGMMVVYRIIESMNGTIRIESEIHKGTTVSIYL 222 >4PU9-A nrPDB Length = 398 Score = 31.6 bits (70), Expect = 0.66, Method: Compositional matrix adjust. Identities = 21/67 (31%), Positives = 33/67 (49%), Gaps = 8/67 (11%) Query: 258 KSPGQPIQVVYVPSHLYHMVFELFKNAMRATMEHHANRGVYPPIQVHVTLGNEDLTVKMS 317 K PG I + L+HMVFE+ NA+ + H ++ VT+ + D +V + Sbjct: 27 KRPGMYIGDTDDGTGLHHMVFEVVDNAIDEALAGHCK-------EIIVTI-HADNSVSVQ 78 Query: 318 DRGGGVP 324 D G G+P Sbjct: 79 DDGRGIP 85 >5MMP-A nrPDB Length = 234 Score = 31.6 bits (70), Expect = 0.80, Method: Compositional matrix adjust. Identities = 24/75 (32%), Positives = 38/75 (50%), Gaps = 10/75 (13%) Query: 252 LEELNA--KSPGQPIQVVYVPSHLYHMVFELFKNAMRATMEHHANRGVYPPIQVHVTLGN 309 L+ L+A K PG I + L+HMVFE+ NA+ + H ++ VT+ + Sbjct: 27 LKGLDAVRKRPGMYIGDTDDGTGLHHMVFEVVDNAIDEALAGHCK-------EIIVTI-H 78 Query: 310 EDLTVKMSDRGGGVP 324 D +V + D G G+P Sbjct: 79 ADNSVSVQDDGRGIP 93 >5CPH-A nrPDB Length = 212 Score = 30.8 bits (68), Expect = 1.3, Method: Compositional matrix adjust. Identities = 15/53 (28%), Positives = 31/53 (58%), Gaps = 8/53 (15%) Query: 273 LYHMVFELFKNAMRATMEHHANRGVYPPIQVHVTLGNEDLTVKMSDRGGGVPL 325 L+H+V+E+ N++ + +AN Q+ V + +D +K++D G G+P+ Sbjct: 45 LHHLVWEIVDNSIDEALAGYAN-------QIEVVI-EKDNWIKVTDNGRGIPV 89 >4RLP-A nrPDB Length = 288 Score = 30.0 bits (66), Expect = 1.8, Method: Compositional matrix adjust. Identities = 21/92 (22%), Positives = 39/92 (42%), Gaps = 8/92 (8%) Query: 116 QSLQELLDFK--DKSAEDAKAIYDFTDTV------IRIRNRHNDVIPTMAQGVIEYKESF 167 Q +L DF +S D + F T+ I +R+ HN + + G + Y Sbjct: 145 QGHVKLTDFGLCKESIHDGTVTHTFCGTIEYMAPEILMRSGHNRAVDWWSLGALMYDMLT 204 Query: 168 GVDPVTSQNVQYFLDRFYMSRISIRMLLNQHS 199 G P T +N + +D+ ++++ L Q + Sbjct: 205 GAPPFTGENRKKTIDKILKCKLNLPPYLTQEA 236 >4URM-A nrPDB Length = 231 Score = 30.0 bits (66), Expect = 1.9, Method: Compositional matrix adjust. Identities = 15/53 (28%), Positives = 31/53 (58%), Gaps = 8/53 (15%) Query: 273 LYHMVFELFKNAMRATMEHHANRGVYPPIQVHVTLGNEDLTVKMSDRGGGVPL 325 L+H+V+E+ N++ + +AN Q+ V + +D +K++D G G+P+ Sbjct: 44 LHHLVWEIVDNSIDEALAGYAN-------QIEVVI-EKDNWIKVTDNGRGIPV 88 >4URL-A nrPDB Length = 406 Score = 29.6 bits (65), Expect = 2.9, Method: Compositional matrix adjust. Identities = 14/52 (26%), Positives = 30/52 (57%), Gaps = 8/52 (15%) Query: 273 LYHMVFELFKNAMRATMEHHANRGVYPPIQVHVTLGNEDLTVKMSDRGGGVP 324 L+H+V+E+ N++ + + N ++ VT+ N+D ++ + D G G+P Sbjct: 39 LHHLVYEIVDNSVDEVLNGYGN-------EIDVTI-NKDGSISIEDNGRGMP 82 >4URN-A nrPDB Length = 225 Score = 29.6 bits (65), Expect = 2.9, Method: Compositional matrix adjust. Identities = 21/86 (24%), Positives = 40/86 (46%), Gaps = 17/86 (19%) Query: 273 LYHMVFELFKNAMRATMEHHANRGVYPPIQVHVTLGNEDLTVKMSDRGGGVPLRKIDRLF 332 L+H+V+E+ N++ + + N ++ VT+ N+D ++ + D G G+P Sbjct: 39 LHHLVYEIVDNSVDEVLNGYGN-------EIDVTI-NKDGSISIEDNGRGMPTG------ 84 Query: 333 NYMYSTAPRPRVETSRAVPLAGFGYG 358 + +P VE V AG +G Sbjct: 85 ---IHKSGKPTVEVIFTVLHAGGKFG 107 >4L42-A nrPDB Length = 346 Score = 29.3 bits (64), Expect = 3.3, Method: Compositional matrix adjust. Identities = 21/92 (22%), Positives = 39/92 (42%), Gaps = 8/92 (8%) Query: 116 QSLQELLDFK--DKSAEDAKAIYDFTDTV------IRIRNRHNDVIPTMAQGVIEYKESF 167 Q +L DF +S D + F T+ I +R+ HN + + G + Y Sbjct: 158 QGHVKLTDFGLCKESIHDGTVTHTFCGTIEYMAPEILMRSGHNRAVDWWSLGALMYDMLT 217 Query: 168 GVDPVTSQNVQYFLDRFYMSRISIRMLLNQHS 199 G P T +N + +D+ ++++ L Q + Sbjct: 218 GAPPFTGENRKKTIDKILKCKLNLPPYLTQEA 249 >2IE7-A nrPDB Length = 318 Score = 28.9 bits (63), Expect = 4.5, Method: Compositional matrix adjust. Identities = 19/57 (33%), Positives = 32/57 (56%), Gaps = 4/57 (7%) Query: 362 SRLYAQYFQGDLKLYSLEGYGTDAVIYIKALSTDSIERLPVYNKAAWKHYNTNHEAD 418 SRLY Y +LK ++L+G GTD + + +++ + E L +A + Y +N E D Sbjct: 85 SRLYDAY---ELK-HALKGAGTDEKVLTEIIASRTPEELRAIKQAYEEEYGSNLEDD 137 >1XRE-A nrPDB Length = 217 Score = 28.9 bits (63), Expect = 4.6, Method: Compositional matrix adjust. Identities = 15/47 (31%), Positives = 26/47 (55%), Gaps = 1/47 (2%) Query: 316 MSDRGGGVPLRKIDRLFNYMYSTAPRPRVETSR-AVPLAGFGYGLPI 361 MS RGGG P + ++ +Y ++T + + S+ A+ G GYG + Sbjct: 99 MSPRGGGEPNGDVAKVIDYYFNTFDNLKDQLSKAAISRFGSGYGWLV 145 >4R7O-A nrPDB Length = 292 Score = 28.9 bits (63), Expect = 5.0, Method: Compositional matrix adjust. Identities = 19/67 (28%), Positives = 35/67 (52%), Gaps = 7/67 (10%) Query: 373 LKLYSLEGYG-TDAVIYIKALSTDSIERLPVYNKAA------WKHYNTNHEADDWCVPSR 425 L+ Y+L G + + + I++ S DS++++ NK W + N N+E +W + Sbjct: 148 LEKYNLIGQNMSSSRVMIQSFSKDSLKKIHSINKNIPLVQLLWYYPNENNEIVEWSGITH 207 Query: 426 EPKDMTT 432 EPK +T Sbjct: 208 EPKRVTN 214 >4HZ5-A nrPDB Length = 216 Score = 27.7 bits (60), Expect = 9.4, Method: Compositional matrix adjust. Identities = 14/52 (26%), Positives = 31/52 (59%), Gaps = 8/52 (15%) Query: 273 LYHMVFELFKNAMRATMEHHANRGVYPPIQVHVTLGNEDLTVKMSDRGGGVP 324 L+H+V+E+ NA+ + + N +++VT+ +D ++ ++D G G+P Sbjct: 22 LHHLVYEIVDNAVDEALSGYGN-------EINVTI-QKDNSICVADSGRGMP 65 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 2Q8F-A nrPDB 700 0.0 3CRK-A nrPDB 655 0.0 1Y8N-A nrPDB 637 0.0 2E0A-A nrPDB 635 0.0 4DZY-A nrPDB 379 e-105 6AZR-A nrPDB 141 6e-34 4U7O-A nrPDB 126 2e-29 3SL2-A nrPDB 114 6e-26 Sequences not found previously or not previously below threshold: 4I5S-A nrPDB 104 9e-23 5LFK-A nrPDB 66 3e-11 4PL9-A nrPDB 64 1e-10 3D36-A nrPDB 60 2e-09 4Q20-A nrPDB 57 1e-08 4GCZ-A nrPDB 57 2e-08 6BLK-C nrPDB 54 1e-07 1ID0-A nrPDB 52 7e-07 1R62-A nrPDB 51 7e-07 3A0R-A nrPDB 50 2e-06 3A0Y-A nrPDB 50 2e-06 1YSR-A nrPDB 50 2e-06 6DK7-A nrPDB 49 5e-06 3CGZ-A nrPDB 46 3e-05 5IDM-A nrPDB 46 3e-05 5IDJ-A nrPDB 46 3e-05 4XIV-A nrPDB 45 7e-05 1I5D-A nrPDB 45 7e-05 4JPB-A nrPDB 45 8e-05 3JA6-C nrPDB 44 2e-04 2Q2E-B nrPDB 42 5e-04 4KP4-A nrPDB 40 0.002 4CTI-A nrPDB 40 0.002 1BXD-A nrPDB 40 0.002 2ZBK-B nrPDB 37 0.012 1MX0-A nrPDB 37 0.012 3JZ3-A nrPDB 37 0.016 5MMP-A nrPDB 35 0.050 4PU9-A nrPDB 35 0.050 1ZXN-A nrPDB 33 0.35 5CPH-A nrPDB 32 0.38 4URM-A nrPDB 32 0.38 4URN-A nrPDB 32 0.49 4URL-A nrPDB 32 0.49 3ZKD-A nrPDB 32 0.53 1AVC-A nrPDB 32 0.60 1TID-A nrPDB 32 0.68 1KIJ-A nrPDB 32 0.71 4BAE-A nrPDB 32 0.75 4XEM-A nrPDB 31 1.2 4FFM-A nrPDB 31 1.3 1XRE-A nrPDB 30 1.5 1Z8P-A nrPDB 30 1.5 1M9I-A nrPDB 30 1.6 4P7A-A nrPDB 30 2.2 6H6X-B nrPDB 30 2.4 4B6C-A nrPDB 30 2.6 2IOR-A nrPDB 30 2.7 1Y4U-A nrPDB 30 2.7 2IOQ-A nrPDB 30 2.8 3WBH-A nrPDB 29 4.1 4EDN-A nrPDB 29 6.5 4R3A-A nrPDB 28 7.6 4R39-A nrPDB 28 7.6 >2Q8F-A nrPDB Length = 407 Score = 700 bits (1806), Expect = 0.0, Method: Composition-based stats. Identities = 407/407 (100%), Positives = 407/407 (100%) Query: 30 SDSGSSPASERGVPGQVDFYARFSPSPLSMKQFLDFGSVNACEKTSFMFLRQELPVRLAN 89 SDSGSSPASERGVPGQVDFYARFSPSPLSMKQFLDFGSVNACEKTSFMFLRQELPVRLAN Sbjct: 1 SDSGSSPASERGVPGQVDFYARFSPSPLSMKQFLDFGSVNACEKTSFMFLRQELPVRLAN 60 Query: 90 IMKEISLLPDNLLRTPSVQLVQSWYIQSLQELLDFKDKSAEDAKAIYDFTDTVIRIRNRH 149 IMKEISLLPDNLLRTPSVQLVQSWYIQSLQELLDFKDKSAEDAKAIYDFTDTVIRIRNRH Sbjct: 61 IMKEISLLPDNLLRTPSVQLVQSWYIQSLQELLDFKDKSAEDAKAIYDFTDTVIRIRNRH 120 Query: 150 NDVIPTMAQGVIEYKESFGVDPVTSQNVQYFLDRFYMSRISIRMLLNQHSLLFGGKGKGS 209 NDVIPTMAQGVIEYKESFGVDPVTSQNVQYFLDRFYMSRISIRMLLNQHSLLFGGKGKGS Sbjct: 121 NDVIPTMAQGVIEYKESFGVDPVTSQNVQYFLDRFYMSRISIRMLLNQHSLLFGGKGKGS 180 Query: 210 PSHRKHIGSINPNCNVLEVIKDGYENARRLCDLYYINSPELELEELNAKSPGQPIQVVYV 269 PSHRKHIGSINPNCNVLEVIKDGYENARRLCDLYYINSPELELEELNAKSPGQPIQVVYV Sbjct: 181 PSHRKHIGSINPNCNVLEVIKDGYENARRLCDLYYINSPELELEELNAKSPGQPIQVVYV 240 Query: 270 PSHLYHMVFELFKNAMRATMEHHANRGVYPPIQVHVTLGNEDLTVKMSDRGGGVPLRKID 329 PSHLYHMVFELFKNAMRATMEHHANRGVYPPIQVHVTLGNEDLTVKMSDRGGGVPLRKID Sbjct: 241 PSHLYHMVFELFKNAMRATMEHHANRGVYPPIQVHVTLGNEDLTVKMSDRGGGVPLRKID 300 Query: 330 RLFNYMYSTAPRPRVETSRAVPLAGFGYGLPISRLYAQYFQGDLKLYSLEGYGTDAVIYI 389 RLFNYMYSTAPRPRVETSRAVPLAGFGYGLPISRLYAQYFQGDLKLYSLEGYGTDAVIYI Sbjct: 301 RLFNYMYSTAPRPRVETSRAVPLAGFGYGLPISRLYAQYFQGDLKLYSLEGYGTDAVIYI 360 Query: 390 KALSTDSIERLPVYNKAAWKHYNTNHEADDWCVPSREPKDMTTFRSA 436 KALSTDSIERLPVYNKAAWKHYNTNHEADDWCVPSREPKDMTTFRSA Sbjct: 361 KALSTDSIERLPVYNKAAWKHYNTNHEADDWCVPSREPKDMTTFRSA 407 >3CRK-A nrPDB Length = 407 Score = 655 bits (1690), Expect = 0.0, Method: Composition-based stats. Identities = 274/400 (68%), Positives = 340/400 (85%), Gaps = 3/400 (0%) Query: 37 ASERGVPGQVDFYARFSPSPLSMKQFLDFGSVNACEKTSFMFLRQELPVRLANIMKEISL 96 AS G P ++ +++FSPSPLSMKQFLDFGS NACEKTSF FLRQELPVRLANIMKEI+L Sbjct: 11 ASLAGAPKYIEHFSKFSPSPLSMKQFLDFGSSNACEKTSFTFLRQELPVRLANIMKEINL 70 Query: 97 LPDNLLRTPSVQLVQSWYIQSLQELLDFKDKSAEDAKAIYDFTDTVIRIRNRHNDVIPTM 156 LPD +L TPSVQLVQSWY+QSL ++++F DK ED + + FTD ++ IRNRHNDV+PTM Sbjct: 71 LPDRVLSTPSVQLVQSWYVQSLLDIMEFLDKDPEDHRTLSQFTDALVTIRNRHNDVVPTM 130 Query: 157 AQGVIEYKESFGVDPVTSQNVQYFLDRFYMSRISIRMLLNQHSLLFGGKGKGSPSHRKHI 216 AQGV+EYK+++G DPV++QN+QYFLDRFY+SRISIRML+NQH+L+F G +P+H KHI Sbjct: 131 AQGVLEYKDTYGDDPVSNQNIQYFLDRFYLSRISIRMLINQHTLIF--DGSTNPAHPKHI 188 Query: 217 GSINPNCNVLEVIKDGYENARRLCDLYYINSPELELEELNAKSPGQPIQVVYVPSHLYHM 276 GSI+PNC+V +V+KD Y+ A+ LCD YY+ SP+LE++E+NA + QPI +VYVPSHLYHM Sbjct: 189 GSIDPNCSVSDVVKDAYDMAKLLCDKYYMASPDLEIQEVNATNATQPIHMVYVPSHLYHM 248 Query: 277 VFELFKNAMRATMEHHANRGVYPPIQVHVTLGNEDLTVKMSDRGGGVPLRKIDRLFNYMY 336 +FELFKNAMRAT+E H + PPI++ V LG EDL++KMSDRGGGVPLRKI+RLF+YMY Sbjct: 249 LFELFKNAMRATVESHESSLTLPPIKIMVALGEEDLSIKMSDRGGGVPLRKIERLFSYMY 308 Query: 337 STAPRPRVETSRAVPLAGFGYGLPISRLYAQYFQGDLKLYSLEGYGTDAVIYIKALSTDS 396 STAP P+ T PLAGFGYGLPISRLYA+YFQGDL+L+S+EG+GTDAVIY+KALSTDS Sbjct: 309 STAPTPQPGTG-GTPLAGFGYGLPISRLYAKYFQGDLQLFSMEGFGTDAVIYLKALSTDS 367 Query: 397 IERLPVYNKAAWKHYNTNHEADDWCVPSREPKDMTTFRSA 436 +ERLPVYNK+AW+HY T EA DWCVPS EPK+ +T+R + Sbjct: 368 VERLPVYNKSAWRHYQTIQEAGDWCVPSTEPKNTSTYRVS 407 >1Y8N-A nrPDB Length = 419 Score = 637 bits (1644), Expect = 0.0, Method: Composition-based stats. Identities = 271/395 (68%), Positives = 333/395 (84%), Gaps = 3/395 (0%) Query: 42 VPGQVDFYARFSPSPLSMKQFLDFGSVNACEKTSFMFLRQELPVRLANIMKEISLLPDNL 101 VP Q++ Y+RFSPSPLS+KQFLDFG NACEKTS+MFLR+ELPVRLAN M+E++LLPDNL Sbjct: 25 VPKQIERYSRFSPSPLSIKQFLDFGRDNACEKTSYMFLRKELPVRLANTMREVNLLPDNL 84 Query: 102 LRTPSVQLVQSWYIQSLQELLDFKDKSAEDAKAIYDFTDTVIRIRNRHNDVIPTMAQGVI 161 L PSV LVQSWY+QS ELL++++KS ED + + +F +I++RNRHNDV+PTMAQGVI Sbjct: 85 LNRPSVGLVQSWYMQSFLELLEYENKSPEDPQVLDNFLQVLIKVRNRHNDVVPTMAQGVI 144 Query: 162 EYKESFGVDPVTSQNVQYFLDRFYMSRISIRMLLNQHSLLFGGKGKGSPSHRKHIGSINP 221 EYKE FG DP S N+QYFLDRFY +RIS RML+NQH+LLFG G +P H KHIGSI+P Sbjct: 145 EYKEKFGFDPFISTNIQYFLDRFYTNRISFRMLINQHTLLFG--GDTNPVHPKHIGSIDP 202 Query: 222 NCNVLEVIKDGYENARRLCDLYYINSPELELEELNAKSPGQPIQVVYVPSHLYHMVFELF 281 CNV +V+KD YE A+ LC+ YY+ +PELE+EE NAK+P +PIQVVYVPSHL+HM+FELF Sbjct: 203 TCNVADVVKDAYETAKMLCEQYYLVAPELEVEEFNAKAPDKPIQVVYVPSHLFHMLFELF 262 Query: 282 KNAMRATMEHHANRGV-YPPIQVHVTLGNEDLTVKMSDRGGGVPLRKIDRLFNYMYSTAP 340 KN+MRAT+E + +R YP ++ VTLG EDL++K+SD GGGVPLRKIDRLFNYMYSTAP Sbjct: 263 KNSMRATVELYEDRKEGYPAVKTLVTLGKEDLSIKISDLGGGVPLRKIDRLFNYMYSTAP 322 Query: 341 RPRVETSRAVPLAGFGYGLPISRLYAQYFQGDLKLYSLEGYGTDAVIYIKALSTDSIERL 400 RP +E +RA PLAGFGYGLPISRLYA+YFQGDLKLYS+EG GTDAVIY+KALS++S ERL Sbjct: 323 RPSLEPTRAAPLAGFGYGLPISRLYARYFQGDLKLYSMEGVGTDAVIYLKALSSESFERL 382 Query: 401 PVYNKAAWKHYNTNHEADDWCVPSREPKDMTTFRS 435 PV+NK+AW+HY T EADDW PS EP+D + +++ Sbjct: 383 PVFNKSAWRHYKTTPEADDWSNPSSEPRDASKYKA 417 >2E0A-A nrPDB Length = 394 Score = 635 bits (1638), Expect = 0.0, Method: Composition-based stats. Identities = 263/391 (67%), Positives = 330/391 (84%), Gaps = 3/391 (0%) Query: 42 VPGQVDFYARFSPSPLSMKQFLDFGSVNACEKTSFMFLRQELPVRLANIMKEISLLPDNL 101 VP +V+ ++R+SPSPLSMKQ LDFGS NACE+TSF FLRQELPVRLANI+KEI +LP L Sbjct: 3 VPREVEHFSRYSPSPLSMKQLLDFGSENACERTSFAFLRQELPVRLANILKEIDILPTQL 62 Query: 102 LRTPSVQLVQSWYIQSLQELLDFKDKSAEDAKAIYDFTDTVIRIRNRHNDVIPTMAQGVI 161 + T SVQLV+SWYIQSL +L++F +KS +D KA+ DF DT+I++RNRH++V+PTMAQG+I Sbjct: 63 VNTSSVQLVKSWYIQSLMDLVEFHEKSPDDQKALSDFVDTLIKVRNRHHNVVPTMAQGII 122 Query: 162 EYKESFGVDPVTSQNVQYFLDRFYMSRISIRMLLNQHSLLFGGKGKGSPSHRKHIGSINP 221 EYK++ VDPVT+QN+QYFLDRFYM+RIS RML+NQH L+F G+PSH IGSI+P Sbjct: 123 EYKDACTVDPVTNQNLQYFLDRFYMNRISTRMLMNQHILIFSDSQTGNPSH---IGSIDP 179 Query: 222 NCNVLEVIKDGYENARRLCDLYYINSPELELEELNAKSPGQPIQVVYVPSHLYHMVFELF 281 NC+V+ V++D +E +R LCD YY++SPEL+L ++N K P QPI +VYVPSHL+HM+FELF Sbjct: 180 NCDVVAVVQDAFECSRMLCDQYYLSSPELKLTQVNGKFPDQPIHIVYVPSHLHHMLFELF 239 Query: 282 KNAMRATMEHHANRGVYPPIQVHVTLGNEDLTVKMSDRGGGVPLRKIDRLFNYMYSTAPR 341 KNAMRAT+EH N+ PI+V V LG EDLT+K+SDRGGGVPLR IDRLF+Y YSTAP Sbjct: 240 KNAMRATVEHQENQPSLTPIEVIVVLGKEDLTIKISDRGGGVPLRIIDRLFSYTYSTAPT 299 Query: 342 PRVETSRAVPLAGFGYGLPISRLYAQYFQGDLKLYSLEGYGTDAVIYIKALSTDSIERLP 401 P ++ SR PLAGFGYGLPISRLYA+YFQGDL LYSL GYGTDA+IY+KALS++SIE+LP Sbjct: 300 PVMDNSRNAPLAGFGYGLPISRLYAKYFQGDLNLYSLSGYGTDAIIYLKALSSESIEKLP 359 Query: 402 VYNKAAWKHYNTNHEADDWCVPSREPKDMTT 432 V+NK+A+KHY + EADDWC+PSREPK++ Sbjct: 360 VFNKSAFKHYQMSSEADDWCIPSREPKNLAK 390 >4DZY-A nrPDB Length = 418 Score = 379 bits (974), Expect = e-105, Method: Composition-based stats. Identities = 113/342 (33%), Positives = 182/342 (53%), Gaps = 46/342 (13%) Query: 78 FLRQELPVRLANIMKEISLLPDNLLRTPSVQLVQSWYIQSLQELLDF---KDKSAEDAKA 134 +L+QELPVR+A+ +K LP + P++ V YI++ Q+L DF KD++ E Sbjct: 93 YLQQELPVRIAHRIKGFRSLPFIIGCNPTILHVHELYIRAFQKLTDFPPIKDQADE---- 148 Query: 135 IYDFTDTVIRIRNRHNDVIPTMAQGVIEYKESFGVDPVTSQNVQYFLDRFYMSRISIRML 194 + V ++ + H DV+ +A+G+ E ++ + + V+YFLD+ SR+ IRML Sbjct: 149 -AQYCQLVRQLLDDHKDVVTLLAEGLRESRKHIEDEKL----VRYFLDKTLTSRLGIRML 203 Query: 195 LNQHSLLFGGKGKGSPSHRKHIGSINPNCNVLEVIKDGYENARRLCDLYYINSPELELE- 253 H L K +G I + ++I+ + ARRLC+ Y N+P + + Sbjct: 204 ATHHLALHEDKPD-------FVGIICTRLSPKKIIEKWVDFARRLCEHKYGNAPRVRING 256 Query: 254 ELNAKSPGQPIQVVYVPSHLYHMVFELFKNAMRATMEHHANRGVYPPIQVHVTLGNE--D 311 + A+ P ++P L +++ EL KNAMRATME H + P V +T+ N D Sbjct: 257 HVAARFP-------FIPMPLDYILPELLKNAMRATMESHLDTPYNVP-DVVITIANNDVD 308 Query: 312 LTVKMSDRGGGVPLRKIDRLFNYMYSTAPR----PRVET----------SRAVPLAGFGY 357 L +++SDRGGG+ + +DR+ +Y ++TA PR+ ++ P+ GFG+ Sbjct: 309 LIIRISDRGGGIAHKDLDRVMDYHFTTAEASTQDPRISPLFGHLDMHSGGQSGPMHGFGF 368 Query: 358 GLPISRLYAQYFQGDLKLYSLEGYGTDAVIYIKALSTDSIER 399 GLP SR YA+Y G L+L SL+G GTD +Y++ D E Sbjct: 369 GLPTSRAYAEYLGGSLQLQSLQGIGTD--VYLRLRHIDGREE 408 >6AZR-A nrPDB Length = 259 Score = 141 bits (355), Expect = 6e-34, Method: Composition-based stats. Identities = 30/129 (23%), Positives = 57/129 (44%), Gaps = 14/129 (10%) Query: 263 PIQVVYVPSHLYHMVFELFKNAMRATMEHHANRGVYPPIQVHVTLGNED--LTVKMSDRG 320 P++ P+ + ++ L N ++ + + P V V L +D + + + D G Sbjct: 130 PVEAYIDPTRIRQVLLNLLNNGVKYSKKD------APDKYVKVILDEKDGGVLIIVEDNG 183 Query: 321 GGVPLRKIDRLFNYMYSTAPRPRVETSRAVPLAGFGYGLPISRLYAQYFQGDLKLYSLEG 380 G+P DR+F Y RV++S + G G GL I++ + G + + S G Sbjct: 184 IGIPDHAKDRIFEQFY------RVDSSLTYEVPGTGLGLAITKEIVELHGGRIWVESEVG 237 Query: 381 YGTDAVIYI 389 G+ ++I Sbjct: 238 KGSRFFVWI 246 >4U7O-A nrPDB Length = 277 Score = 126 bits (316), Expect = 2e-29, Method: Composition-based stats. Identities = 26/111 (23%), Positives = 53/111 (47%), Gaps = 9/111 (8%) Query: 279 ELFKNAMRATMEHHANRGVYPPIQVHVTLGNEDLTVKMSDRGGGVPLRKIDRLFNYMYST 338 ++ N M +++ + GV + + + + + +SD+G G+P + +F+ + Sbjct: 159 QVLDNIMNNAIKYSPDGGV---VTCRLLETHNQVIISISDQGLGIPRADLGHVFDRFF-- 213 Query: 339 APRPRVETSRAVPLAGFGYGLPISRLYAQYFQGDLKLYSLEGYGTDAVIYI 389 RV+ +R+ G G GL IS+ Q G + + S+EG G+ I + Sbjct: 214 ----RVDKARSRAQGGTGLGLAISKEVVQMLGGRIWVDSVEGKGSTFYISL 260 >3SL2-A nrPDB Length = 177 Score = 114 bits (286), Expect = 6e-26, Method: Composition-based stats. Identities = 33/130 (25%), Positives = 59/130 (45%), Gaps = 11/130 (8%) Query: 254 ELNAKSPGQPIQVVYVPSHLYHMVFELFKNAMRATMEHHANRGVYPPIQVHVTLGNEDLT 313 E P + + V + ++ + NA++ + E G + + V E L Sbjct: 25 EFIRNLPDRDLYVEIDQDKITQVLDNIISNALKYSPE-----GGHVTFSIDVNEEEELLY 79 Query: 314 VKMSDRGGGVPLRKIDRLFNYMYSTAPRPRVETSRAVPLAGFGYGLPISRLYAQYFQGDL 373 + + D G G+P + ++++F+ Y RV+ +R L G G GL I++ Q GD+ Sbjct: 80 ISVKDEGIGIPKKDVEKVFDRFY------RVDKARTRKLGGTGLGLAIAKEMVQAHGGDI 133 Query: 374 KLYSLEGYGT 383 S+EG GT Sbjct: 134 WADSIEGKGT 143 >4I5S-A nrPDB Length = 450 Score = 104 bits (259), Expect = 9e-23, Method: Composition-based stats. Identities = 26/139 (18%), Positives = 62/139 (44%), Gaps = 13/139 (9%) Query: 251 ELEELNAKSPGQPIQVVYVPSHLYHMVFELFKNAMRATMEHHANRGVYPPIQVHVTLGNE 310 ++ E+ P + + + + ++ N + +++ + G + + + + Sbjct: 306 KVYEIIRDYPDKSVWIEIDTDKMTQVI----DNILNNAIKYSPDGGK---VTITMQTTDT 358 Query: 311 DLTVKMSDRGGGVPLRKIDRLFNYMYSTAPRPRVETSRAVPLAGFGYGLPISRLYAQYFQ 370 L + +SD+G G+P + + +F+ Y RV+ +R+ G G GL I++ + + Sbjct: 359 QLILSISDQGLGIPKKDLPLIFDRFY------RVDKARSRAQGGTGLGLAIAKEIVKQHK 412 Query: 371 GDLKLYSLEGYGTDAVIYI 389 G + S EG G+ I + Sbjct: 413 GFIWANSEEGEGSTFTIVL 431 >5LFK-A nrPDB Length = 298 Score = 65.9 bits (159), Expect = 3e-11, Method: Composition-based stats. Identities = 30/135 (22%), Positives = 53/135 (39%), Gaps = 15/135 (11%) Query: 255 LNAKSPGQPIQVVYVPSHLYHMVFELFKNAMRATMEHHANRGVYPPIQVHVTLGNEDLTV 314 L P P + P+ L + + +NA+R + + I+V + + +T+ Sbjct: 173 LTVNFPPGPWPLYGNPNALESALENIVRNALRYS---------HTKIEVGFAVDKDGITI 223 Query: 315 KMSDRGGGVPLRKIDRLFNYMYSTAPRPRVETSRAVPLAGFGYGLPISRLYAQYFQGDLK 374 + D G GV +++F Y R + +R G G GL I Q +G +K Sbjct: 224 TVDDDGPGVSPEDREQIFRPFY------RTDEARDRESGGTGLGLAIVETAIQQHRGWVK 277 Query: 375 LYSLEGYGTDAVIYI 389 G VI++ Sbjct: 278 AEDSPLGGLRLVIWL 292 >4PL9-A nrPDB Length = 183 Score = 64.3 bits (155), Expect = 1e-10, Method: Composition-based stats. Identities = 30/142 (21%), Positives = 53/142 (37%), Gaps = 15/142 (10%) Query: 259 SPGQPIQVVYVPSHLYHMVFELFKNAMRATMEHHANRGVYPPIQ--------VHVTLGNE 310 +P P VV L ++ + NA++ + + + V T + Sbjct: 40 APDLPEFVVGDEKRLMQIILNIVGNAVKFSKQGSISVTALVTKSDTRAADFFVVPTGSHF 99 Query: 311 DLTVKMSDRGGGVPLRKIDRLFNYMYSTAPRPRVETSRAVPLAGFGYGLPISRLYAQYFQ 370 L VK+ D G G+ + I ++F T G G GL IS+ + + Sbjct: 100 YLRVKVKDSGAGINPQDIPKIFTKFAQTQSLA------TRSSGGSGLGLAISKRFVNLME 153 Query: 371 GDLKLYSL-EGYGTDAVIYIKA 391 G++ + S G G A+ +K Sbjct: 154 GNIWIESDGLGKGCTAIFDVKL 175 >3D36-A nrPDB Length = 244 Score = 59.7 bits (143), Expect = 2e-09, Method: Composition-based stats. Identities = 34/172 (19%), Positives = 67/172 (38%), Gaps = 23/172 (13%) Query: 227 EVIKDGYENARRLCDLYYINSPELELEELN------AKSPGQPIQVVYVPSHL---YHMV 277 +I D A+ + + +LE+E + A IQ P + Sbjct: 65 AIITDYLTFAKPAPETPEKLNVKLEIERVIDILRPLANMSCVDIQATLAPFSVIGEREKF 124 Query: 278 FELFKNAMRATMEHHANRGVYPPIQVHVTLGNEDLTVKMSDRGGGVPLRKIDRLFNYMYS 337 + N M+ +E N G QV+V++ N + ++++D G G+ +++RL ++ Sbjct: 125 RQCLLNVMKNAIEAMPNGGTL---QVYVSIDNGRVLIRIADTGVGMTKEQLERLGEPYFT 181 Query: 338 TAPRPRVETSRAVPLAGFGYGLPISRLYAQYFQGDLKLYSLEGYGTDAVIYI 389 T + G G G+ + + G +++ S GT IY+ Sbjct: 182 TKG-----------VKGTGLGMMVVYRIIESMNGTIRIESEIHKGTTVSIYL 222 >4Q20-A nrPDB Length = 268 Score = 57.4 bits (137), Expect = 1e-08, Method: Composition-based stats. Identities = 26/122 (21%), Positives = 42/122 (34%), Gaps = 27/122 (22%) Query: 272 HLYHMVFELFKNAMRATMEHHANRGVYPPIQVHVTLGNE----DLTVKMSDRGGGVPLRK 327 L + L +NA+R T P VTL ++ + +SD G GVP Sbjct: 155 RLAQTLDHLVENALRQT-----------PPGGRVTLSARRALGEVRLDVSDTGRGVPFHV 203 Query: 328 IDRLFNYMYSTAPRPRVETSRAVPLAGFGYGLPISRLYAQYFQGDLKLYSLEGYGTDAVI 387 +F+ G G GL + + + G + L S G G+ Sbjct: 204 QAHIFDRFV------------GRDRGGPGLGLALVKALVELHGGWVALESEPGNGSTFTC 251 Query: 388 YI 389 ++ Sbjct: 252 HL 253 >4GCZ-A nrPDB Length = 385 Score = 56.6 bits (135), Expect = 2e-08, Method: Composition-based stats. Identities = 30/144 (20%), Positives = 49/144 (34%), Gaps = 20/144 (13%) Query: 251 ELEELNAKSPGQPIQ--VVYVPSHLYHMVFELFKNAMRATMEHHANRGVYPPIQVHVTLG 308 + + + P V+ + ++ LF+NA+ A + V T Sbjct: 245 REQNVQLRFSLDPGADLVLADRVQIQQVLVNLFRNALEAMAQSQRRELVVTN-----TPA 299 Query: 309 NEDLT-VKMSDRGGGVPLRKIDRLFNYMYSTAPRPRVETSRAVPLAGFGYGLPISRLYAQ 367 +D+ V++SD G G I LF ++T G G GL ISR + Sbjct: 300 ADDMIEVEVSDTGSGFQDDVIPNLFQTFFTTKDT------------GMGVGLSISRSIIE 347 Query: 368 YFQGDLKLYSLEGYGTDAVIYIKA 391 G + S G + A Sbjct: 348 AHGGRMWAESNASGGATFRFTLPA 371 >6BLK-C nrPDB Length = 158 Score = 53.9 bits (128), Expect = 1e-07, Method: Composition-based stats. Identities = 25/114 (21%), Positives = 45/114 (39%), Gaps = 14/114 (12%) Query: 263 PIQVVYVPSHLYHMVFELFKNAMRATMEHHANRGVYPPIQVHVTLGNEDLTVKMSDRGGG 322 P QV+ S L V + NA + + G + G+ +L + +D+G G Sbjct: 37 PWQVIGDSSGLGRAVLNVLDNAAKWS----PPGGRVGVRLYQIDPGHAELVI--TDQGPG 90 Query: 323 VPLRKIDRLFNYMYSTAPRPRVETSRAVPLAGFGYGLPISRLYAQYFQGDLKLY 376 +P ++ +F + +A A + G G GL I + G L++ Sbjct: 91 IPPQERHLVFERFFRSAS--------ARSMPGSGLGLAIVKQVVLKHGGALRVD 136 >1ID0-A nrPDB Length = 152 Score = 51.6 bits (122), Expect = 7e-07, Method: Composition-based stats. Identities = 28/125 (22%), Positives = 53/125 (42%), Gaps = 20/125 (16%) Query: 275 HMVFELFKNAMRATMEHHANRGVYPPIQVHVTLGNEDLTVKMSDRGGGVPLRKIDRLFNY 334 ++ + NA + +E +++ +E L + + D G G+PL K + +F+ Sbjct: 47 EVMGNVLDNACKYCLEF---------VEISARQTDEHLYIVVEDDGPGIPLSKREVIFDR 97 Query: 335 MYSTAPRPRVETSRAVPLAGFGYGLPISRLYAQYFQGDLKL-YSLEGYGTDAVIYIKALS 393 RV+T R G G GL ++R + ++G + S+ G VI+ + S Sbjct: 98 ------GQRVDTLR----PGQGVGLAVAREITEQYEGKIVAGESMLGGARMEVIFGRQHS 147 Query: 394 TDSIE 398 E Sbjct: 148 APKDE 152 >1R62-A nrPDB Length = 160 Score = 51.3 bits (121), Expect = 7e-07, Method: Composition-based stats. Identities = 34/170 (20%), Positives = 64/170 (37%), Gaps = 19/170 (11%) Query: 227 EVIKDGYENARRLCDLYYINSPELELEELNAKSPGQPIQVVYVPSHLYHMVFELFKNAMR 286 V + ++ A R+ L + P+ + + P P ++ + P + ++ + +NA++ Sbjct: 5 RVTESIHKVAERVVTLVSMELPD-NVRLIRDYDPSLP-ELAHDPDQIEQVLLNIVRNALQ 62 Query: 287 ATMEHHANRGVYPPIQVHVTLGNED----LTVKMSDRGGGVPLRKIDRLFNYMYSTAPRP 342 A + +TL E + + D G G+P D LF M S Sbjct: 63 ALGPEGGEIILRTRTAFQLTLHGERYRLAARIDVEDNGPGIPPHLQDTLFYPMVSGRE-- 120 Query: 343 RVETSRAVPLAGFGYGLPISRLYAQYFQGDLKLYSLEGYGTDAVIYIKAL 392 G G GL I+R G ++ S G+ T+ +Y+ Sbjct: 121 ----------GGTGLGLSIARNLIDQHSGKIEFTSWPGH-TEFSVYLPIR 159 >3A0R-A nrPDB Length = 349 Score = 50.1 bits (118), Expect = 2e-06, Method: Composition-based stats. Identities = 31/208 (14%), Positives = 75/208 (36%), Gaps = 44/208 (21%) Query: 190 SIRMLLNQHSLLFGGKGKGSPSHRKHIGSINPNCNVLE-VIKDGYENAR----------- 237 M + +H + +K+I I + LE ++K+ E ++ Sbjct: 152 GFIMRMKKHL----DDPET---LKKYINIITNELSRLETIVKEILEYSKERQVLEFTEFN 204 Query: 238 ---RLCDLYYINSPELELEELNAKSPG--QPIQVVYVPSHLYHMVFELFKNAMRATMEHH 292 + ++Y + ++ ++ + ++V + + ++ L +NA+ AT E+ Sbjct: 205 LNELIREVYVLFEEKIRKMNIDFCFETDNEDLRVEADRTRIKQVLINLVQNAIEATGENG 264 Query: 293 ANRGVYPPIQVHVTLGNEDLTVKMSDRGGGVPLRKIDRLFNYMYSTAPRPRVETSRAVPL 352 + + V V + + G +P +++F+ ++T + Sbjct: 265 KIKITSEDMYTKVR-------VSVWNSGPPIPEELKEKIFSPFFTTKTQ----------- 306 Query: 353 AGFGYGLPISRLYAQ-YFQGDLKLYSLE 379 G G GL I R + G + + E Sbjct: 307 -GTGLGLSICRKIIEDEHGGKIWTENRE 333 >3A0Y-A nrPDB Length = 152 Score = 50.1 bits (118), Expect = 2e-06, Method: Composition-based stats. Identities = 20/112 (17%), Positives = 42/112 (37%), Gaps = 20/112 (17%) Query: 269 VPSHLYHMVFELFKNAMRATMEHHANRGVYPPIQVHVTLGNEDLTVKMSDRGGGVPLRKI 328 + + ++ L +NA+ AT E+ + + V V + + G +P Sbjct: 44 DRTRIKQVLINLVQNAIEATGENGKIKITSEDMYTKVR-------VSVWNSGPPIPEELK 96 Query: 329 DRLFNYMYSTAPRPRVETSRAVPLAGFGYGLPISRLYAQ-YFQGDLKLYSLE 379 +++F+ ++T + G G GL I R + G + + E Sbjct: 97 EKIFSPFFTTKTQ------------GTGLGLSICRKIIEDEHGGKIWTENRE 136 >1YSR-A nrPDB Length = 150 Score = 50.1 bits (118), Expect = 2e-06, Method: Composition-based stats. Identities = 23/140 (16%), Positives = 45/140 (32%), Gaps = 10/140 (7%) Query: 251 ELEELNAK-SPGQPIQVVYVPSHLYHMVFELFKNAMRATMEHHANRGVYPPIQVHVTLGN 309 A+ P + +V P+ + + + A+ + + G +Q+ Sbjct: 16 RAAHDAARIYPDLDVSLVPSPTCIIVGLPAGLRLAVDNAIANAVKHGGATLVQLSAVSSR 75 Query: 310 EDLTVKMSDRGGGVPLRKIDRLFNYMYSTAPRPRVETSRAVPLAGFGYGLPISRLYAQYF 369 + + + D G GVP + +F +G G GL + AQ Sbjct: 76 AGVEIAIDDNGSGVPEGERQVVFERF---------SRGSTASHSGSGLGLALVAQQAQLH 126 Query: 370 QGDLKLYSLEGYGTDAVIYI 389 G L + G V+ + Sbjct: 127 GGTASLENSPLGGARLVLRL 146 >6DK7-A nrPDB Length = 227 Score = 48.9 bits (115), Expect = 5e-06, Method: Composition-based stats. Identities = 34/164 (20%), Positives = 60/164 (36%), Gaps = 25/164 (15%) Query: 224 NVLEVIKDGYENARRLCDLYYINSPELELEELNAKSPGQPIQVVYVPSHLYHMVFELFKN 283 ++ +I+D + R + +E ++ P P + P+ L +V L N Sbjct: 74 DLNALIEDCLDIFRVKAEQQ-------RIELISFTQPQVPRVIGGDPTRLRQVVLSLLDN 126 Query: 284 AMRATMEHHANRGVYPPIQVHVTLGNE----DLTVKMSDRGGGVPLRKIDRLFNYMYSTA 339 A + T E I + V L ++ L + + D G ++ + L TA Sbjct: 127 AFKQTEEGE--------ILLVVALDDQGETPRLRIAVQDSGHPFDAKEREALL-----TA 173 Query: 340 PRPRVETSRAVPLAGFGYGLPISRLYAQYFQGDLKLYSLEGYGT 383 + A L G GL I+R + G+ + S GT Sbjct: 174 ELHSGDFLSASKL-GSHLGLIIARQLVRLMGGEFGIQSGSSQGT 216 >3CGZ-A nrPDB Length = 157 Score = 46.2 bits (108), Expect = 3e-05, Method: Composition-based stats. Identities = 25/125 (20%), Positives = 49/125 (39%), Gaps = 20/125 (16%) Query: 275 HMVFELFKNAMRATMEHHANRGVYPPIQVHVTLGNEDLTVKMSDRGGGVPLRKIDRLFNY 334 ++ + NA + +E +++ ++ L + + D G G+P K +F+ Sbjct: 52 EVMGNVLDNACKYCLEF---------VEISARQTDDHLHIFVEDDGPGIPHSKRSLVFDR 102 Query: 335 MYSTAPRPRVETSRAVPLAGFGYGLPISRLYAQYFQGDLKL-YSLEGYGTDAVIYIKALS 393 R +T R G G GL ++R + + G + SL G V++ + Sbjct: 103 ------GQRADTLR----PGQGVGLAVAREITEQYAGQIIASDSLLGGARMEVVFGRQHP 152 Query: 394 TDSIE 398 T E Sbjct: 153 TQKEE 157 >5IDM-A nrPDB Length = 179 Score = 46.2 bits (108), Expect = 3e-05, Method: Composition-based stats. Identities = 28/136 (20%), Positives = 47/136 (34%), Gaps = 22/136 (16%) Query: 265 QVVYVPSHLYHMVFELFKNAMRATMEHHANRGVYPPIQVHVTLGN-----------EDLT 313 QV S L V L NA R + GV +T + Sbjct: 39 QVRADKSQLETAVMNLAVNA-RDAVRAAKGGGVVRIRTARLTRDEAIQLGFPAADGDTAF 97 Query: 314 VKMSDRGGGVPLRKIDRLFNYMYSTAPRPRVETSRAVPLAGFGYGLPISRLYAQYFQGDL 373 +++SD G G+P + ++F+ ++T P G G GL + G + Sbjct: 98 IEVSDDGPGIPPDVMGKIFDPFFTTKPVGE----------GTGLGLATVYGIVKQSDGWI 147 Query: 374 KLYSLEGYGTDAVIYI 389 ++S G I++ Sbjct: 148 HVHSRPNEGAAFRIFL 163 >5IDJ-A nrPDB Length = 242 Score = 46.2 bits (108), Expect = 3e-05, Method: Composition-based stats. Identities = 28/136 (20%), Positives = 47/136 (34%), Gaps = 22/136 (16%) Query: 265 QVVYVPSHLYHMVFELFKNAMRATMEHHANRGVYPPIQVHVTLGN-----------EDLT 313 QV S L V L NA R + GV +T + Sbjct: 113 QVRADKSQLETAVMNLAVNA-RDAVRAAKGGGVVRIRTARLTRDEAIQLGFPAADGDTAF 171 Query: 314 VKMSDRGGGVPLRKIDRLFNYMYSTAPRPRVETSRAVPLAGFGYGLPISRLYAQYFQGDL 373 +++SD G G+P + ++F+ ++T P G G GL + G + Sbjct: 172 IEVSDDGPGIPPDVMGKIFDPFFTTKPVGE----------GTGLGLATVYGIVKQSDGWI 221 Query: 374 KLYSLEGYGTDAVIYI 389 ++S G I++ Sbjct: 222 HVHSRPNEGAAFRIFL 237 >4XIV-A nrPDB Length = 252 Score = 44.7 bits (104), Expect = 7e-05, Method: Composition-based stats. Identities = 23/138 (16%), Positives = 49/138 (35%), Gaps = 28/138 (20%) Query: 277 VFELFKNAMRATMEHHANR--GVYPPIQVHVTLGN---EDLTVKMSDRGGGVPLRKIDR- 330 + L +NA+ +E R PPI + ++ +++ D G G+ KI R Sbjct: 115 LLHLLRNAIDHGIEPKEERIAKGKPPIGTLILSARHEGNNVVIEVEDDGRGIDKEKIIRK 174 Query: 331 -------------------LFNYMYSTAPRPRVETSRAVPLAGFGYGLPISRLYAQYFQG 371 + N+++ + ++G G G+ + + + G Sbjct: 175 AIEKGLIDESKAATLSDQEILNFLFVPGFST---KEKVSEVSGRGVGMDVVKNVVESLNG 231 Query: 372 DLKLYSLEGYGTDAVIYI 389 + + S + GT I + Sbjct: 232 SISIESEKDKGTKVTIRL 249 >1I5D-A nrPDB Length = 191 Score = 44.7 bits (104), Expect = 7e-05, Method: Composition-based stats. Identities = 23/138 (16%), Positives = 49/138 (35%), Gaps = 28/138 (20%) Query: 277 VFELFKNAMRATMEHHANR--GVYPPIQVHVTLGN---EDLTVKMSDRGGGVPLRKIDR- 330 + L +NA+ +E R PPI + ++ +++ D G G+ KI R Sbjct: 54 LLHLLRNAIDHGIEPKEERIAKGKPPIGTLILSARHEGNNVVIEVEDDGRGIDKEKIIRK 113 Query: 331 -------------------LFNYMYSTAPRPRVETSRAVPLAGFGYGLPISRLYAQYFQG 371 + N+++ + ++G G G+ + + + G Sbjct: 114 AIEKGLIDESKAATLSDQEILNFLFVPGFST---KEKVSEVSGRGVGMDVVKNVVESLNG 170 Query: 372 DLKLYSLEGYGTDAVIYI 389 + + S + GT I + Sbjct: 171 SISIESEKDKGTKVTIRL 188 >4JPB-A nrPDB Length = 319 Score = 44.7 bits (104), Expect = 8e-05, Method: Composition-based stats. Identities = 24/134 (17%), Positives = 47/134 (35%), Gaps = 21/134 (15%) Query: 277 VFELFKNAMRATMEHHANR--GVYPPIQVHVTLGN---EDLTVKMSDRGGGVPLRKIDR- 330 + L +NA+ +E R PPI + ++ +++ D G G+ KI R Sbjct: 52 LLHLLRNAIDHGIEPKEERIAKGKPPIGTLILSARHEGNNVVIEVEDDGRGIDKEKIIRK 111 Query: 331 --------------LFNYMYSTAPRPRVE-TSRAVPLAGFGYGLPISRLYAQYFQGDLKL 375 L + P + ++G G G+ + + + G + + Sbjct: 112 AIEKGLIDESKAATLSDQEILNFLVPGFSTKEKVSEVSGRGVGMDVVKNVVESLNGSISI 171 Query: 376 YSLEGYGTDAVIYI 389 S + GT I + Sbjct: 172 ESEKDKGTKVTIRL 185 >3JA6-C nrPDB Length = 379 Score = 43.5 bits (101), Expect = 2e-04, Method: Composition-based stats. Identities = 23/138 (16%), Positives = 49/138 (35%), Gaps = 28/138 (20%) Query: 277 VFELFKNAMRATMEHHANR--GVYPPIQVHVTLGN---EDLTVKMSDRGGGVPLRKIDR- 330 + L +NA+ +E R PPI + ++ +++ D G G+ KI R Sbjct: 111 LLHLLRNAIDHGIEPKEERIAKGKPPIGTLILSARHEGNNVVIEVEDDGRGIDKEKIIRK 170 Query: 331 -------------------LFNYMYSTAPRPRVETSRAVPLAGFGYGLPISRLYAQYFQG 371 + N+++ + ++G G G+ + + + G Sbjct: 171 AIEKGLIDESKAATLSDQEILNFLFVPGFST---KEKVSEVSGRGVGMDVVKNVVESLNG 227 Query: 372 DLKLYSLEGYGTDAVIYI 389 + + S + GT I + Sbjct: 228 SMGIESEKDKGTKVTIRL 245 >2Q2E-B nrPDB Length = 621 Score = 42.0 bits (97), Expect = 5e-04, Method: Composition-based stats. Identities = 24/97 (24%), Positives = 41/97 (42%), Gaps = 5/97 (5%) Query: 277 VFELFKNAMRATMEHHANRGVYPPIQVHVTLGNED-LTVKMSDRGGGVPLRKIDRLFNYM 335 + K A+ ++ G+ P I V V D +TV + D G G+ +I ++F + Sbjct: 38 LITTVKEAVDNALDACEEAGILPDILVQVERTGPDYVTVIIEDNGPGIVREQIPKVFAKL 97 Query: 336 YSTAPRPRVETSRAVPLAGFGYGLPISRLYAQYFQGD 372 + ++ SR G G+ + LYAQ G Sbjct: 98 LYGSRFHALKQSRGQQ----GIGISAAVLYAQMTAGR 130 >4KP4-A nrPDB Length = 236 Score = 40.5 bits (93), Expect = 0.002, Method: Composition-based stats. Identities = 30/133 (22%), Positives = 48/133 (36%), Gaps = 18/133 (13%) Query: 257 AKSPGQPIQVVYVPSHLYHMVFELFKNAMRATMEHHANRGVYPPIQVHVTLGNEDLTVKM 316 A PG I+V P + V + NA R I+V ++ Sbjct: 108 ALYPGS-IEVKMHPLSIKRAVANMVVNAARYG---------NGWIKVSSGTEPNRAWFQV 157 Query: 317 SDRGGGVPLRKIDRLFNYMYSTAPRPRVETSRAVPLAGFGYGLPISRLYAQYFQGDLKLY 376 D G G+ + LF P R +++R ++G G GL I + G L+L Sbjct: 158 EDDGPGIAPEQRKHLFQ------PFVRGDSART--ISGTGLGLAIVQRIVDNHNGMLELG 209 Query: 377 SLEGYGTDAVIYI 389 + E G ++ Sbjct: 210 TSERGGLSIRAWL 222 >4CTI-A nrPDB Length = 273 Score = 40.5 bits (93), Expect = 0.002, Method: Composition-based stats. Identities = 30/133 (22%), Positives = 48/133 (36%), Gaps = 18/133 (13%) Query: 257 AKSPGQPIQVVYVPSHLYHMVFELFKNAMRATMEHHANRGVYPPIQVHVTLGNEDLTVKM 316 A PG I+V P + V + NA R I+V ++ Sbjct: 145 ALYPGS-IEVKMHPLSIKRAVANMVVNAARYG---------NGWIKVSSGTEPNRAWFQV 194 Query: 317 SDRGGGVPLRKIDRLFNYMYSTAPRPRVETSRAVPLAGFGYGLPISRLYAQYFQGDLKLY 376 D G G+ + LF P R +++R ++G G GL I + G L+L Sbjct: 195 EDDGPGIAPEQRKHLFQ------PFVRGDSART--ISGTGLGLAIVQRIVDNHNGMLELG 246 Query: 377 SLEGYGTDAVIYI 389 + E G ++ Sbjct: 247 TSERGGLSIRAWL 259 >1BXD-A nrPDB Length = 161 Score = 40.5 bits (93), Expect = 0.002, Method: Composition-based stats. Identities = 30/133 (22%), Positives = 48/133 (36%), Gaps = 18/133 (13%) Query: 257 AKSPGQPIQVVYVPSHLYHMVFELFKNAMRATMEHHANRGVYPPIQVHVTLGNEDLTVKM 316 A PG I+V P + V + NA R I+V ++ Sbjct: 33 ALYPGS-IEVKMHPLSIKRAVANMVVNAARYG---------NGWIKVSSGTEPNRAWFQV 82 Query: 317 SDRGGGVPLRKIDRLFNYMYSTAPRPRVETSRAVPLAGFGYGLPISRLYAQYFQGDLKLY 376 D G G+ + LF P R +++R ++G G GL I + G L+L Sbjct: 83 EDDGPGIAPEQRKHLFQ------PFVRGDSART--ISGTGLGLAIVQRIVDNHNGMLELG 134 Query: 377 SLEGYGTDAVIYI 389 + E G ++ Sbjct: 135 TSERGGLSIRAWL 147 >2ZBK-B nrPDB Length = 530 Score = 37.4 bits (85), Expect = 0.012, Method: Composition-based stats. Identities = 28/102 (27%), Positives = 47/102 (46%), Gaps = 14/102 (13%) Query: 273 LYHMVFELFKNAMRATMEHHANRGVYPPIQVHVTL---GNEDLTVKMSDRGGGVPLRKID 329 LY V EL +N++ AT H G+ P I++ + L + V + D G G+P +++ Sbjct: 32 LYQTVRELIENSLDATDVH----GILPNIKITIDLIDDARQIYKVNVVDNGIGIPPQEVP 87 Query: 330 RLFNY-MYSTAPRPRVETSRAVPLAGFGYGLPISRLYAQYFQ 370 F +YS+ R +G G+ + LY+Q Q Sbjct: 88 NAFGRVLYSSKYVNRQTRGM------YGLGVKAAVLYSQMHQ 123 >1MX0-A nrPDB Length = 472 Score = 37.4 bits (85), Expect = 0.012, Method: Composition-based stats. Identities = 28/102 (27%), Positives = 47/102 (46%), Gaps = 14/102 (13%) Query: 273 LYHMVFELFKNAMRATMEHHANRGVYPPIQVHVTL---GNEDLTVKMSDRGGGVPLRKID 329 LY V EL +N++ AT H G+ P I++ + L + V + D G G+P +++ Sbjct: 34 LYQTVRELIENSLDATDVH----GILPNIKITIDLIDDARQIYKVNVVDNGIGIPPQEVP 89 Query: 330 RLFNY-MYSTAPRPRVETSRAVPLAGFGYGLPISRLYAQYFQ 370 F +YS+ R +G G+ + LY+Q Q Sbjct: 90 NAFGRVLYSSKYVNRQTRGM------YGLGVKAAVLYSQMHQ 125 >3JZ3-A nrPDB Length = 222 Score = 37.0 bits (84), Expect = 0.016, Method: Composition-based stats. Identities = 19/98 (19%), Positives = 35/98 (35%), Gaps = 10/98 (10%) Query: 294 NRGVYPPIQVHVTLGNEDLTVKMSDRGGGVPLRKIDRLFNYMYSTAPRPRVETSRAVPLA 353 N Y P V + + D G GV + R+ Y + Sbjct: 128 NAVRYSPQGSVVDVTLNADNFIVRDNGPGVTPEALARIGERFYRP-------PGQTA--T 178 Query: 354 GFGYGLPISRLYAQYFQGDLKLYSLEGYGTDAVI-YIK 390 G G GL I + A+ +++ + E G +A + +++ Sbjct: 179 GSGLGLSIVQRIAKLHGMNVEFGNAEQGGFEAKVSWLE 216 >5MMP-A nrPDB Length = 234 Score = 35.5 bits (80), Expect = 0.050, Method: Composition-based stats. Identities = 21/67 (31%), Positives = 33/67 (49%), Gaps = 8/67 (11%) Query: 258 KSPGQPIQVVYVPSHLYHMVFELFKNAMRATMEHHANRGVYPPIQVHVTLGNEDLTVKMS 317 K PG I + L+HMVFE+ NA+ + H ++ VT+ + D +V + Sbjct: 35 KRPGMYIGDTDDGTGLHHMVFEVVDNAIDEALAGHC-------KEIIVTI-HADNSVSVQ 86 Query: 318 DRGGGVP 324 D G G+P Sbjct: 87 DDGRGIP 93 >4PU9-A nrPDB Length = 398 Score = 35.5 bits (80), Expect = 0.050, Method: Composition-based stats. Identities = 21/67 (31%), Positives = 33/67 (49%), Gaps = 8/67 (11%) Query: 258 KSPGQPIQVVYVPSHLYHMVFELFKNAMRATMEHHANRGVYPPIQVHVTLGNEDLTVKMS 317 K PG I + L+HMVFE+ NA+ + H ++ VT+ + D +V + Sbjct: 27 KRPGMYIGDTDDGTGLHHMVFEVVDNAIDEALAGHC-------KEIIVTI-HADNSVSVQ 78 Query: 318 DRGGGVP 324 D G G+P Sbjct: 79 DDGRGIP 85 >1ZXN-A nrPDB Length = 400 Score = 32.8 bits (73), Expect = 0.35, Method: Composition-based stats. Identities = 30/157 (19%), Positives = 58/157 (36%), Gaps = 30/157 (19%) Query: 244 YINSPELELEELNAKSPGQPI---QVVYVPSHLYHMVFELFKNAMRATMEHHANRGVYPP 300 YI S EL +++ I +V +VP LY + E+ NA Sbjct: 22 YIGSVELVTQQMWVYDEDVGINYREVTFVPG-LYKIFDEILVNAADNKQRDPKMSC---- 76 Query: 301 IQVHVTLGNEDLTVKMSDRGGGVP--LRKIDR------LFNYMYSTAPRPRVETSRAVPL 352 + VT+ E+ + + + G G+P K+++ +F + +++ E Sbjct: 77 --IRVTIDPENNLISIWNNGKGIPVVEHKVEKMYVPALIFGQLLTSSNYDDDEKKVTGGR 134 Query: 353 AGFGYGL-----------PISRLYAQYFQGDLKLYSL 378 G+G L SR Y + F+ + ++ Sbjct: 135 NGYGAKLCNIFSTKFTVETASREYKKMFK-QTWMDNM 170 >5CPH-A nrPDB Length = 212 Score = 32.4 bits (72), Expect = 0.38, Method: Composition-based stats. Identities = 15/59 (25%), Positives = 35/59 (59%), Gaps = 8/59 (13%) Query: 273 LYHMVFELFKNAMRATMEHHANRGVYPPIQVHVTLGNEDLTVKMSDRGGGVPLRKIDRL 331 L+H+V+E+ N++ + +AN+ I+V + +D +K++D G G+P+ +++ Sbjct: 45 LHHLVWEIVDNSIDEALAGYANQ-----IEVVI---EKDNWIKVTDNGRGIPVDIQEKM 95 >4URM-A nrPDB Length = 231 Score = 32.4 bits (72), Expect = 0.38, Method: Composition-based stats. Identities = 15/59 (25%), Positives = 35/59 (59%), Gaps = 8/59 (13%) Query: 273 LYHMVFELFKNAMRATMEHHANRGVYPPIQVHVTLGNEDLTVKMSDRGGGVPLRKIDRL 331 L+H+V+E+ N++ + +AN+ I+V + +D +K++D G G+P+ +++ Sbjct: 44 LHHLVWEIVDNSIDEALAGYANQ-----IEVVI---EKDNWIKVTDNGRGIPVDIQEKM 94 >4URN-A nrPDB Length = 225 Score = 32.0 bits (71), Expect = 0.49, Method: Composition-based stats. Identities = 18/91 (19%), Positives = 42/91 (46%), Gaps = 15/91 (16%) Query: 273 LYHMVFELFKNAMRATMEHHANRGVYPPIQVHVTLGNEDLTVKMSDRGGGVP-------L 325 L+H+V+E+ N++ + + N ++ VT+ N+D ++ + D G G+P Sbjct: 39 LHHLVYEIVDNSVDEVLNGYGN-------EIDVTI-NKDGSISIEDNGRGMPTGIHKSGK 90 Query: 326 RKIDRLFNYMYSTAPRPRVETSRAVPLAGFG 356 ++ +F +++ + + L G G Sbjct: 91 PTVEVIFTVLHAGGKFGQGGYKTSGGLHGVG 121 >4URL-A nrPDB Length = 406 Score = 32.0 bits (71), Expect = 0.49, Method: Composition-based stats. Identities = 18/91 (19%), Positives = 42/91 (46%), Gaps = 15/91 (16%) Query: 273 LYHMVFELFKNAMRATMEHHANRGVYPPIQVHVTLGNEDLTVKMSDRGGGVP-------L 325 L+H+V+E+ N++ + + N ++ VT+ N+D ++ + D G G+P Sbjct: 39 LHHLVYEIVDNSVDEVLNGYGN-------EIDVTI-NKDGSISIEDNGRGMPTGIHKSGK 90 Query: 326 RKIDRLFNYMYSTAPRPRVETSRAVPLAGFG 356 ++ +F +++ + + L G G Sbjct: 91 PTVEVIFTVLHAGGKFGQGGYKTSGGLHGVG 121 >3ZKD-A nrPDB Length = 432 Score = 32.0 bits (71), Expect = 0.53, Method: Composition-based stats. Identities = 19/91 (20%), Positives = 39/91 (42%), Gaps = 15/91 (16%) Query: 273 LYHMVFELFKNAMRATMEHHANRGVYPPIQVHVTLGNEDLTVKMSDRGGGVPLR------ 326 L+H+++E+ NA+ M G + V + ED V+++D G G+P+ Sbjct: 47 LHHLIWEVVDNAVDEAM-----AGYATTVNVVLL---EDGGVEVADDGRGIPVATHASGI 98 Query: 327 -KIDRLFNYMYSTAPRPRVETSRAVPLAGFG 356 +D + +++ + + L G G Sbjct: 99 PTVDVVMTQLHAGGKFDSDAYAISGGLHGVG 129 >1AVC-A nrPDB Length = 673 Score = 32.0 bits (71), Expect = 0.60, Method: Composition-based stats. Identities = 33/165 (20%), Positives = 63/165 (38%), Gaps = 4/165 (2%) Query: 253 EELNAKSPGQPIQVVYVPSHLYHMVFELFKNAMRATMEHHANRGVYPPIQVHVTLG-NED 311 ++ + + QV Y L + K +R + + + + LG +ED Sbjct: 325 DDAAGQFFPEAAQVAYQMWELSAVARVELKGTVRPAGDFNPDADAKALRKAMKGLGTDED 384 Query: 312 LTVKMSDRGGGVPLRKIDRLFNYMYSTAPRPRVETSRAVPLAGFGYGLPISRLYAQYFQG 371 + + ++I + F + +++ + LA GL + A Y Sbjct: 385 TIIDIITHRSNAQRQQIRQTFKSHFGRDLMADLKSELSGDLARLILGLMMPP--AHYDAK 442 Query: 372 DLKLYSLEGYGTDAVIYIKALSTDSIERLPVYNKAAWKHYNTNHE 416 LK ++EG GTD I+ L+T + + NKA + Y+ E Sbjct: 443 QLK-KAMEGAGTDEKALIEILATRTNAEIQAINKAYKEDYHKTLE 486 >1TID-A nrPDB Length = 136 Score = 31.6 bits (70), Expect = 0.68, Method: Composition-based stats. Identities = 21/111 (18%), Positives = 42/111 (37%), Gaps = 18/111 (16%) Query: 280 LFKNAMRATMEHHANRGVYPPIQVHVTLGNEDLTVKMSDRGGGVPLRKIDRLFNYMYSTA 339 + A+ + H N + + V + + + + + D G G+P I+ +++T Sbjct: 43 VVSEAVTNAIIHGYNNDPNGIVSISVIIEDGVVHLTVRDEGVGIP--DIEEARQPLFTTK 100 Query: 340 PRPRVETSRAVPLAGFGYGLPISRLYAQYFQGDLKLYSLEGYGTDAVIYIK 390 P L G G I + F ++ + S GT +Y+K Sbjct: 101 P----------ELERSGMGFTI----MENFMDEVIVESEVNKGT--TVYLK 135 >1KIJ-A nrPDB Length = 390 Score = 31.6 bits (70), Expect = 0.71, Method: Composition-based stats. Identities = 19/91 (20%), Positives = 37/91 (40%), Gaps = 16/91 (17%) Query: 274 YHMVFELFKNAMRATMEHHANRGVYPPIQVHVTLGNEDLTVKMSDRGGGVP--------L 325 +H+ E+ NA+ + G I V + NED ++ + D G G+P Sbjct: 34 HHLFKEILDNAVDEAL-----AGYATEILVRL---NEDGSLTVEDNGRGIPVDLMPEEGK 85 Query: 326 RKIDRLFNYMYSTAPRPRVETSRAVPLAGFG 356 ++ ++N ++S + + L G G Sbjct: 86 PAVEVIYNTLHSGGKFEQGAYKVSGGLHGVG 116 >4BAE-A nrPDB Length = 205 Score = 31.6 bits (70), Expect = 0.75, Method: Composition-based stats. Identities = 19/91 (20%), Positives = 39/91 (42%), Gaps = 15/91 (16%) Query: 273 LYHMVFELFKNAMRATMEHHANRGVYPPIQVHVTLGNEDLTVKMSDRGGGVPLR------ 326 L+H+++E+ NA+ M G + V + + D +V++ D G G+P+ Sbjct: 24 LHHLIWEVVDNAVDEAM-----AGFATRVDVKI---HADGSVEVRDDGRGIPVEMHATGM 75 Query: 327 -KIDRLFNYMYSTAPRPRVETSRAVPLAGFG 356 ID + +++ + + L G G Sbjct: 76 PTIDVVMTQLHAGGKFDGETYAVSGGLHGVG 106 >4XEM-A nrPDB Length = 475 Score = 30.8 bits (68), Expect = 1.2, Method: Composition-based stats. Identities = 23/154 (14%), Positives = 46/154 (29%), Gaps = 13/154 (8%) Query: 219 INPNCNVLEVIKDGYENARRLCDLYYINSPELELEELNAKSPGQPIQVVYVPSHLYHMVF 278 ++ E+ + + +R + Y+ +A P +++ + + Sbjct: 21 MDSTLTASEIRQRFIDFFKR-NEHTYV--------HSSATIPLDDPTLLFANAGMNQFKP 71 Query: 279 ELFKNAMRATMEHHANRGVYPPIQVHVTLGNEDLTVKMSDRGGGVPLRKIDRLFNYMYST 338 + +R + + DL D G V + Sbjct: 72 IFLNTIDPSHPMAKLSRAANTQKCIRAGGKHNDL----DDVGKDVYHHTFFEMLGSWSFG 127 Query: 339 APRPRVETSRAVPLAGFGYGLPISRLYAQYFQGD 372 + A+ L +G+PI RLY YF GD Sbjct: 128 DYFKELACKMALELLTQEFGIPIERLYVTYFGGD 161 >4FFM-A nrPDB Length = 363 Score = 30.8 bits (68), Expect = 1.3, Method: Composition-based stats. Identities = 16/71 (22%), Positives = 29/71 (40%), Gaps = 3/71 (4%) Query: 250 LELEELNAKSPGQPIQVVYVPSHLYHMVFELFKNAMRATMEHHANRGVYP-PIQVHVTLG 308 L + E++A+ P Q VVY S + + EL A +E I H+ G Sbjct: 235 LRVIEIDARFPSQTPTVVYYSSGIN--LIELLFRAFTDGVEEIRAIPENKYCIYEHLMFG 292 Query: 309 NEDLTVKMSDR 319 + + + ++ Sbjct: 293 ENGVLIPVGEQ 303 >1XRE-A nrPDB Length = 217 Score = 30.5 bits (67), Expect = 1.5, Method: Composition-based stats. Identities = 15/44 (34%), Positives = 24/44 (54%), Gaps = 1/44 (2%) Query: 316 MSDRGGGVPLRKIDRLFNYMYSTAPRPRVETSRAV-PLAGFGYG 358 MS RGGG P + ++ +Y ++T + + S+A G GYG Sbjct: 99 MSPRGGGEPNGDVAKVIDYYFNTFDNLKDQLSKAAISRFGSGYG 142 >1Z8P-A nrPDB Length = 404 Score = 30.5 bits (67), Expect = 1.5, Method: Composition-based stats. Identities = 34/156 (21%), Positives = 51/156 (32%), Gaps = 25/156 (16%) Query: 258 KSPGQPIQVVYVPSHLYHMVFELFK------NAMRATMEHHANRGVYPPIQVHVTLGNED 311 P Q V PS L + V E+ + R E GV P V + N Sbjct: 259 THPDQLALVRRDPSALPNAVEEILRYIAPPETTTRFAAEEVEIGGVAIPQYSTVLVAN-- 316 Query: 312 LTVKMSDRGGGVPLRKIDRLFNYM-YSTAPRPRVETSRAVPLAGFGYGLPISRL----YA 366 G R + + + R S + F G P+++L Sbjct: 317 ----------GAANRDPKQFPDPHRFDVTRDTRGHLSFGQGIH-FCMGRPLAKLEGEVAL 365 Query: 367 QYFQGDLKLYSLEGYGTDAVIYIKALSTDSIERLPV 402 + G SL G D V++ ++L I+ LPV Sbjct: 366 RALFGRFPALSL-GIDADDVVWRRSLLLRGIDHLPV 400 >1M9I-A nrPDB Length = 672 Score = 30.5 bits (67), Expect = 1.6, Method: Composition-based stats. Identities = 33/165 (20%), Positives = 65/165 (39%), Gaps = 4/165 (2%) Query: 253 EELNAKSPGQPIQVVYVPSHLYHMVFELFKNAMRATMEHHANRGVYPPIQVHVTLG-NED 311 ++ + + QV Y L + K +R + + + + LG +ED Sbjct: 324 DDAAGQFFPEAAQVAYQMWELSAVARVELKGDVRPANDFNPDADAKALRKAMKGLGTDED 383 Query: 312 LTVKMSDRGGGVPLRKIDRLFNYMYSTAPRPRVETSRAVPLAGFGYGLPISRLYAQYFQG 371 + + V ++I + F + +++ + LA GL + A Y Sbjct: 384 TIIDIITHRSNVQRQQIRQTFKSHFGRDLMTDLKSEISGDLARLILGLMMPP--AHYDAK 441 Query: 372 DLKLYSLEGYGTDAVIYIKALSTDSIERLPVYNKAAWKHYNTNHE 416 LK ++EG GTD I+ L+T + + N+A + Y+ + E Sbjct: 442 QLK-KAMEGAGTDEKALIEILATRTNAEIRAINEAYKEDYHKSLE 485 >4P7A-A nrPDB Length = 348 Score = 30.1 bits (66), Expect = 2.2, Method: Composition-based stats. Identities = 13/56 (23%), Positives = 26/56 (46%), Gaps = 2/56 (3%) Query: 283 NAMRATMEHHANRGVYPPIQVHVTLGNEDLTVKMSDRGGGVPLRKIDRLFNYMYST 338 NA++ +E+ + IQV V G L +++ D G G+ +D + ++ Sbjct: 31 NAIKEMIENCLDAKS-TSIQVIVKEGGLKL-IQIQDNGTGIRKEDLDIVCERFTTS 84 >6H6X-B nrPDB Length = 448 Score = 29.7 bits (65), Expect = 2.4, Method: Composition-based stats. Identities = 21/97 (21%), Positives = 35/97 (36%), Gaps = 8/97 (8%) Query: 242 LYYI-NSPELELEELNAKSPGQPIQVVYVPSHLYHMVFELFKNAMRATMEHHANRGVYPP 300 YY +P +E QP+ +P+ H++ R + R P Sbjct: 262 RYYGPAAPRPVVEVTAVTHRRQPVYHTIIPASREHLL---LGGIAREAVLLQTVRQNVPT 318 Query: 301 IQ-VHVTLGNE---DLTVKMSDRGGGVPLRKIDRLFN 333 ++ VH+T G + + + G R ID FN Sbjct: 319 VKNVHLTPGGSCRYHAVISIEKKHEGEAKRAIDAAFN 355 >4B6C-A nrPDB Length = 196 Score = 29.7 bits (65), Expect = 2.6, Method: Composition-based stats. Identities = 14/52 (26%), Positives = 27/52 (51%), Gaps = 8/52 (15%) Query: 273 LYHMVFELFKNAMRATMEHHANRGVYPPIQVHVTLGNEDLTVKMSDRGGGVP 324 L+H+++E+ NA+ M G + V + + D +V++ D G G+P Sbjct: 35 LHHLIWEVVDNAVDEAM-----AGFATRVDVKI---HADGSVEVRDDGRGIP 78 >2IOR-A nrPDB Length = 235 Score = 29.7 bits (65), Expect = 2.7, Method: Composition-based stats. Identities = 18/76 (23%), Positives = 30/76 (39%), Gaps = 10/76 (13%) Query: 264 IQVVYVPSHLYHMVFELFKNAMRATMEHHANRGVYPPIQ-------VHVTLGNEDLTVKM 316 I +Y ++ + EL NA A + P + V V+ + T+ + Sbjct: 41 IHSLYSNKEIF--LRELISNASDAADKLRFRALSNPDLYEGDGELRVRVSFDKDKRTLTI 98 Query: 317 SDRGGGVPLRK-IDRL 331 SD G G+ + ID L Sbjct: 99 SDNGVGMTRDEVIDHL 114 >1Y4U-A nrPDB Length = 559 Score = 29.7 bits (65), Expect = 2.7, Method: Composition-based stats. Identities = 18/76 (23%), Positives = 30/76 (39%), Gaps = 10/76 (13%) Query: 264 IQVVYVPSHLYHMVFELFKNAMRATMEHHANRGVYPPIQ-------VHVTLGNEDLTVKM 316 I +Y ++ + EL NA A + P + V V+ + T+ + Sbjct: 21 IHSLYSNKEIF--LRELISNASDAADKLRFRALSNPDLYEGDGELRVRVSFDKDKRTLTI 78 Query: 317 SDRGGGVPLRK-IDRL 331 SD G G+ + ID L Sbjct: 79 SDNGVGMTRDEVIDHL 94 >2IOQ-A nrPDB Length = 624 Score = 29.7 bits (65), Expect = 2.8, Method: Composition-based stats. Identities = 18/76 (23%), Positives = 30/76 (39%), Gaps = 10/76 (13%) Query: 264 IQVVYVPSHLYHMVFELFKNAMRATMEHHANRGVYPPIQ-------VHVTLGNEDLTVKM 316 I +Y ++ + EL NA A + P + V V+ + T+ + Sbjct: 21 IHSLYSNKEIF--LRELISNASDAADKLRFRALSNPDLYEGDGELRVRVSFDKDKRTLTI 78 Query: 317 SDRGGGVPLRK-IDRL 331 SD G G+ + ID L Sbjct: 79 SDNGVGMTRDEVIDHL 94 >3WBH-A nrPDB Length = 527 Score = 28.9 bits (63), Expect = 4.1, Method: Composition-based stats. Identities = 45/233 (19%), Positives = 77/233 (33%), Gaps = 28/233 (12%) Query: 198 HSLLFGGKGKGSPSHRKHIGSINPNCNVLEVIKDGYENARRLCDLYYINSPE--LELEEL 255 H L G S +H + ++ C+ ++ Y + + N E LEL + Sbjct: 71 HQLAKEGVVGFSLTHPEDAVVVDSACSATQLASGIYSGSEVIGIDAEGNPVETVLELAQA 130 Query: 256 NAKSPGQPIQVVYVPSHLYHMVFELFKNAMRATMEHHANRGVYPPIQVHVTLGNEDLTVK 315 K+ G + + L H F H +R + I V + D+ + Sbjct: 131 RGKATG-----LVSDTRLTHATPAAF-------AAHQPHRSLENEIAVDMLEVGPDVMLS 178 Query: 316 MSDRGGG----VP-----LRKIDRLFNYMYSTAPRPRVETSRAVPLAGFGYGLPISRLYA 366 GG VP ++ L + Y A + + + + GYGL SR Sbjct: 179 -----GGLRHWVPQSASEDAEVTSLMDGAYEPASKRQDDRNLLAEAVEKGYGLAFSREQL 233 Query: 367 QYFQGDLKLYSLEGYGTDAVIYIKALSTDSIERLPVYNKAAWKHYNTNHEADD 419 + Q D L G I + D+ R P ++ N + +D Sbjct: 234 EADQSDKLLGLFANSGMADGIEYRNTRDDADRREPTLHEMTQAALNRLEQDED 286 >4EDN-A nrPDB Length = 133 Score = 28.5 bits (62), Expect = 6.5, Method: Composition-based stats. Identities = 13/70 (18%), Positives = 26/70 (37%), Gaps = 11/70 (15%) Query: 243 YYINSPELELEELNAKSPGQP--------IQVVYVPSHLYHMVFELFKNAMRA---TMEH 291 ++N LE+ EL + ++ +VP H +++ E F + E Sbjct: 35 KHLNKLNLEVTELETQFADGVYLVLLMGLLEDYFVPLHHFYLTPESFDQKVHNVSFAFEL 94 Query: 292 HANRGVYPPI 301 + G+ P Sbjct: 95 MLDGGLKKPK 104 >4R3A-A nrPDB Length = 352 Score = 28.1 bits (61), Expect = 7.6, Method: Composition-based stats. Identities = 16/70 (22%), Positives = 28/70 (40%), Gaps = 6/70 (8%) Query: 255 LNAKSPGQPIQVVYVPSHLYHMVFELFKNAMRATMEHHANRGVYPPIQVHVTLGNEDLTV 314 + A + P++ + +V E+ NA++ A+ V V E L V Sbjct: 231 VQADTVDVPVETA---GRIGLLVSEVLTNALQHAFSDRASGVVQLRSSVM---SGEQLRV 284 Query: 315 KMSDRGGGVP 324 + D G G+P Sbjct: 285 TVEDDGRGIP 294 >4R39-A nrPDB Length = 232 Score = 28.1 bits (61), Expect = 7.6, Method: Composition-based stats. Identities = 16/70 (22%), Positives = 28/70 (40%), Gaps = 6/70 (8%) Query: 255 LNAKSPGQPIQVVYVPSHLYHMVFELFKNAMRATMEHHANRGVYPPIQVHVTLGNEDLTV 314 + A + P++ + +V E+ NA++ A+ V V E L V Sbjct: 111 VQADTVDVPVETA---GRIGLLVSEVLTNALQHAFSDRASGVVQLRSSVM---SGEQLRV 164 Query: 315 KMSDRGGGVP 324 + D G G+P Sbjct: 165 TVEDDGRGIP 174 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.311 0.131 0.356 Lambda K H 0.267 0.0404 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 16,849,190 Number of Sequences: 36641 Number of extensions: 681981 Number of successful extensions: 1851 Number of sequences better than 10.0: 65 Number of HSP's better than 10.0 without gapping: 39 Number of HSP's successfully gapped in prelim test: 50 Number of HSP's that attempted gapping in prelim test: 1754 Number of HSP's gapped (non-prelim): 91 length of query: 436 length of database: 10,336,785 effective HSP length: 100 effective length of query: 336 effective length of database: 6,672,685 effective search space: 2242022160 effective search space used: 2242022160 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 60 (27.7 bits)