BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q15024 (291 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 6D6Q-E nrPDB 591 e-169 2PO2-B nrPDB 130 5e-31 2WNR-A nrPDB 123 8e-29 3L7Z-A nrPDB 117 6e-27 2BA1-H nrPDB 113 8e-26 6D6R-C nrPDB 107 5e-24 2NN6-A nrPDB 90 9e-19 6H25-A nrPDB 89 2e-18 4OO1-A nrPDB 81 5e-16 5K36-E nrPDB 70 8e-13 2PO0-A nrPDB 40 0.001 2JEA-B nrPDB 36 0.019 1E3H-A nrPDB 35 0.028 2WNR-B nrPDB 35 0.038 3H1C-A nrPDB 34 0.091 3CDI-A nrPDB 33 0.12 3B4T-A nrPDB 31 0.70 5Y6T-A nrPDB 30 1.1 3HKM-A nrPDB 30 1.1 6D6Q-B nrPDB 30 1.3 6D6K-A nrPDB 29 2.2 3DD6-A nrPDB 29 3.1 3LL3-A nrPDB 28 3.3 4BDV-A nrPDB 28 3.9 4NBQ-A nrPDB 28 4.6 3U1K-A nrPDB 28 4.8 1OYR-A nrPDB 28 5.1 5MMM-c nrPDB 28 5.4 4AIM-A nrPDB 28 5.8 >6D6Q-E nrPDB Length = 293 Score = 591 bits (1523), Expect = e-169, Method: Compositional matrix adjust. Identities = 291/291 (100%), Positives = 291/291 (100%) Query: 1 MASVTLSEAEKVYIVHGVQEDLRVDGRGCEDYRCVEVETDVVSNTSGSARVKLGHTDILV 60 MASVTLSEAEKVYIVHGVQEDLRVDGRGCEDYRCVEVETDVVSNTSGSARVKLGHTDILV Sbjct: 3 MASVTLSEAEKVYIVHGVQEDLRVDGRGCEDYRCVEVETDVVSNTSGSARVKLGHTDILV 62 Query: 61 GVKAEMGTPKLEKPNEGYLEFFVDCSASATPEFEGRGGDDLGTEIANTLYRIFNNKSSVD 120 GVKAEMGTPKLEKPNEGYLEFFVDCSASATPEFEGRGGDDLGTEIANTLYRIFNNKSSVD Sbjct: 63 GVKAEMGTPKLEKPNEGYLEFFVDCSASATPEFEGRGGDDLGTEIANTLYRIFNNKSSVD 122 Query: 121 LKTLCISPREHCWVLYVDVLLLECGGNLFDAISIAVKAALFNTRIPRVRVLEDEEGSKDI 180 LKTLCISPREHCWVLYVDVLLLECGGNLFDAISIAVKAALFNTRIPRVRVLEDEEGSKDI Sbjct: 123 LKTLCISPREHCWVLYVDVLLLECGGNLFDAISIAVKAALFNTRIPRVRVLEDEEGSKDI 182 Query: 181 ELSDDPYDCIRLSVENVPCIVTLCKIGYRHVVDATLQEEACSLASLLVSVTSKGVVTCMR 240 ELSDDPYDCIRLSVENVPCIVTLCKIGYRHVVDATLQEEACSLASLLVSVTSKGVVTCMR Sbjct: 183 ELSDDPYDCIRLSVENVPCIVTLCKIGYRHVVDATLQEEACSLASLLVSVTSKGVVTCMR 242 Query: 241 KVGKGSLDPESIFEMMETGKRVGKVLHASLQSVVHKEESLGPKRQKVGFLG 291 KVGKGSLDPESIFEMMETGKRVGKVLHASLQSVVHKEESLGPKRQKVGFLG Sbjct: 243 KVGKGSLDPESIFEMMETGKRVGKVLHASLQSVVHKEESLGPKRQKVGFLG 293 >2PO2-B nrPDB Length = 277 Score = 130 bits (328), Expect = 5e-31, Method: Compositional matrix adjust. Identities = 89/262 (33%), Positives = 143/262 (54%), Gaps = 7/262 (2%) Query: 13 YIVHGVQEDLRVDGRGCEDYRCVEVETDVVSNTSGSARVKLGHTDILVGVKAEMGTPKLE 72 +I++ ++E R+D RG EDYR +E+E V+ GSA VKLG T +LVG+K +G P + Sbjct: 17 HIINLLKEGKRIDDRGFEDYRPIEIEVGVIEKAEGSALVKLGSTQVLVGIKTSLGEPFPD 76 Query: 73 KPNEGYLEFFVDCSASATPEFEGRGGDDLGTEIANTLYRIFNNKSSVDLKTLCISPREHC 132 PN G + V+ A+P FE D+ E+A + R +++L+ + I P + Sbjct: 77 TPNMGVMTTNVELVPLASPTFEPGPPDERAIELARVIDRGIRESKALNLEKMVIVPGKIV 136 Query: 133 WVLYVDVLLLECGGNLFDAISIAVKAALFNTRIPRVRVLEDEEGSKDIELSDDPYDCIRL 192 V+++DV +L+ GNL DAI IA AAL N R+P+VR E+ + ++E D + L Sbjct: 137 RVVFIDVHVLDHDGNLMDAIGIAAIAALLNARVPKVRYNEE---TGEVETLD---ETEPL 190 Query: 193 SVENVPCIVTLCKIGYRHVVDATLQEEACSLASLLVSVTSKGVVTCMRKVGKGSLDPESI 252 VE +P VT KIG VVD +L EE + ++ G ++ ++K G+ E + Sbjct: 191 PVEKIPVPVTFAKIGNILVVDPSLDEELVMDGKITITTDETGHISAVQKSEGGAFKLEEV 250 Query: 253 FEMMETG-KRVGKVLHASLQSV 273 +ET K+ ++ L++V Sbjct: 251 MYAVETAFKKAEEIRKLILEAV 272 >2WNR-A nrPDB Length = 271 Score = 123 bits (309), Expect = 8e-29, Method: Compositional matrix adjust. Identities = 80/242 (33%), Positives = 126/242 (52%), Gaps = 7/242 (2%) Query: 6 LSEAEKVYIVHGVQEDLRVDGRGCEDYRCVEVETDVVSNTSGSARVKLGHTDILVGVKAE 65 + E + I + R+DGR ++R + +ET V+S GS+RVKLG+T I+VGVK + Sbjct: 8 IPEITRKSITDLINNKERIDGRSLHEFRDISIETGVISKAEGSSRVKLGNTQIIVGVKPQ 67 Query: 66 MGTPKLEKPNEGYLEFFVDCSASATPEFEGRGGDDLGTEIANTLYRIFNNKSSVDLKTLC 125 +G P + P G + + A+P FE D+ E++ + R +DL+ LC Sbjct: 68 IGEPFPDTPEMGVILTNSELLPMASPTFEPGPPDERSVELSRVVDRCIRESRMIDLEKLC 127 Query: 126 ISPREHCWVLYVDVLLLECGGNLFDAISIAVKAALFNTRIPRVRVLEDEEGSKDIELSDD 185 I W+L++D+ +++ GNLFDA +A AAL +TRIP V +D E+ + Sbjct: 128 IIEGSKVWMLFLDLHIIDYDGNLFDAAVLATVAALLDTRIPAAEV-------EDGEVVIN 180 Query: 186 PYDCIRLSVENVPCIVTLCKIGYRHVVDATLQEEACSLASLLVSVTSKGVVTCMRKVGKG 245 L V + T KIG V+D +L+EE A + + VT +G + M+K G+G Sbjct: 181 REKMQPLPVNRKALMCTFAKIGNEIVLDPSLEEEDILTARISIGVTEEGSICAMQKGGEG 240 Query: 246 SL 247 L Sbjct: 241 PL 242 >3L7Z-A nrPDB Length = 271 Score = 117 bits (293), Expect = 6e-27, Method: Compositional matrix adjust. Identities = 76/248 (30%), Positives = 124/248 (50%), Gaps = 12/248 (4%) Query: 14 IVHGVQEDLRVDGRGCEDYRCVEVETDVVSNTSGSARVKLGHTDILVGVKAEMGTPKLEK 73 IV ++ +R DGR DYR + + D GSA VKLG T +L G K E+ P + Sbjct: 19 IVSLFEKGIRQDGRKLTDYRPLSITLDYAKKADGSALVKLGTTMVLAGTKLEIDKPYEDT 78 Query: 74 PNEGYLEFFVDCSASATPEFEGRGGDDLGTEIANTLYRIFNNKSSVDLKTLCISPREHCW 133 PN+G L V+ A FE D+ E+A + R + ++DL L I P + W Sbjct: 79 PNQGNLIVNVELLPLAYTTFEPGPPDENAIELARVVDRSLRDSKALDLTKLVIEPGKSVW 138 Query: 134 VLYVDVLLLECGGNLFDAISIAVKAALFNTRIPRVRVLEDEEGSKDIELSDDPYDCIRLS 193 +++DV +L+ GGN+ DA ++A AAL+NT++ +V ++S + + + Sbjct: 139 TVWLDVYVLDYGGNVLDACTLASVAALYNTKVYKVE-----------QISVNKNEVVGKL 187 Query: 194 VENVPCI-VTLCKIGYRHVVDATLQEEACSLASLLVSVTSKGVVTCMRKVGKGSLDPESI 252 N P + +++ K+ VVD L EE+ A + S T + ++K GKGS+ + I Sbjct: 188 PLNYPVVTISVAKVDKYLVVDPDLDEESIMDAKISFSYTPDLKIVGIQKSGKGSMSLQDI 247 Query: 253 FEMMETGK 260 + T + Sbjct: 248 DQAENTAR 255 >2BA1-H nrPDB Length = 259 Score = 113 bits (283), Expect = 8e-26, Method: Compositional matrix adjust. Identities = 79/273 (28%), Positives = 138/273 (50%), Gaps = 14/273 (5%) Query: 1 MASVTLSEAEKVYIVHGVQEDLRVDGRGCEDYRCVEVETDVVSNTSGSARVKLGHTDILV 60 M L + ++ Y++ ++++ R+DGRG +++R VE+ +V+ GSA VKLG T ++V Sbjct: 1 MPEDILVDIKRDYVLSKLRDNERIDGRGFDEFRKVEIIPNVIEKAEGSALVKLGDTQVVV 60 Query: 61 GVKAEMGTPKLEKPNEGYLEFFVDCSASATPEFEGRGGDDLGTEIANTLYRIFNNKSSVD 120 GVK + G P + P+ G + + A+P FE D+ E+A + R +VD Sbjct: 61 GVKMQPGEPYPDTPDRGVIIVNAELVPLASPTFEPGPPDENSIELARVVDRGIRESEAVD 120 Query: 121 LKTLCISPREHCWVLYVDVLLLECGGNLFDAISIAVKAALFNTRIPRVRVLEDEEGSKDI 180 L L I E W+++VD+ L+ GNL DA ++A AAL NT++P R Sbjct: 121 LSKLVIEEGEKVWIVFVDIHALDDDGNLLDASALAAIAALMNTKVPAER----------F 170 Query: 181 ELSDDPYDCIRLSVENVPCIVTLCKIGYRHVVDATLQEEACSLASLLVSVTSKGVVTCMR 240 +L +D L V ++P VT +G +++VD + +E + +L ++ V M+ Sbjct: 171 DLGED----YLLPVRDLPVSVTSLIVGNKYLVDPSREEMSVGDTTLTITTDKDDNVVAMQ 226 Query: 241 KVGKGSLDPESIFEMMETGKRVGKVLHASLQSV 273 K G LD + E+++ + L + + Sbjct: 227 KSGGYLLDEKLFDELLDVSINCARKLREKFKEI 259 >6D6R-C nrPDB Length = 278 Score = 107 bits (268), Expect = 5e-24, Method: Compositional matrix adjust. Identities = 75/269 (27%), Positives = 126/269 (46%), Gaps = 10/269 (3%) Query: 13 YIVHGVQEDLRVDGRGCEDYRCVEVETDVVSNTSGSARVKLGHTDILVGVKAEMGTPKLE 72 Y ++E+ R DGR ++R V +S GSA VKLG+T ++ GVKAE P + Sbjct: 15 YYRRFLKENCRPDGRELGEFRTTTVNIGSISTADGSALVKLGNTTVICGVKAEFAAPSTD 74 Query: 73 KPNEGYLEFFVDCSASATPEFEGRGGDDLGTEIANTLYRIFNNKSSVDLKTLCISPREHC 132 P++GY+ VD + F + + + + N + + LCISP + Sbjct: 75 APDKGYVVPNVDLPPLCSSRFRSGPPGEEAQVASQFIADVIENSQIIQKEDLCISPGKLV 134 Query: 133 WVLYVDVLLLECGGNLFDAISIAVKAALFNTRIPRVRVLEDEEGSKDIELSDDPYDCIRL 192 WVLY D++ L+ GN+ DA + A+ AAL N ++P V + E E ++ L Y L Sbjct: 135 WVLYCDLICLDYDGNILDACTFALLAALKNVQLPEVTINE-ETALAEVNLKKKSY----L 189 Query: 193 SVENVPCIVTLCKI-GYRHVVDATLQEEACSLASLLVSVTSKGVVTCMRKVGKGSLDPES 251 ++ P + +VD T +EE + +L + + +G + C+ K G L Sbjct: 190 NIRTHPVATSFAVFDDTLLIVDPTGEEEHLATGTLTIVMDEEGKLCCLHKPGGSGLTGAK 249 Query: 252 IFEMMETG----KRVGKVLHASLQSVVHK 276 + + M K V K++ ++S+ K Sbjct: 250 LQDCMSRAVTRHKEVKKLMDEVIKSMKPK 278 >2NN6-A nrPDB Length = 358 Score = 90.1 bits (222), Expect = 9e-19, Method: Compositional matrix adjust. Identities = 74/240 (30%), Positives = 115/240 (47%), Gaps = 10/240 (4%) Query: 1 MASVTLSEAEKVYIVHGVQEDLRVDGRGCEDYRCVEVETDVVSNTSGSARVKLGHTDILV 60 M LS E+ +++ ++E R+DGR DYR + + G V+LG T +L Sbjct: 18 MKETPLSNCERRFLLRAIEEKKRLDGRQTYDYRNIRIS---FGTDYGCCIVELGKTRVLG 74 Query: 61 GVKAEMGTPKLEKPNEGYLEFFVDCSASATPEFEGRGGDDLGTEIANTLYRIFNNKSSVD 120 V E+ +PKL + EG L F ++ S A P FE DL ++ + R N +D Sbjct: 75 QVSCELVSPKLNRATEGILFFNLELSQMAAPAFEPGRQSDLLVKLNRLMERCLRNSKCID 134 Query: 121 LKTLCISPREHCWVLYVDVLLLECGGNLFDAISIAVKAALFNTRIPRVRVLEDEEGSKDI 180 ++LC+ E W + VD+ LL GN+ DA SIA AL + R P V V +G + Sbjct: 135 TESLCVVAGEKVWQIRVDLHLLNHDGNIIDAASIAAIVALCHFRRPDVSV----QGDEVT 190 Query: 181 ELSDDPYDCIRLSVENVPCIVTLC--KIGYRHVVDATLQEEACSLASLLVSVTSKGVVTC 238 + + D + LS+ ++P V+ + G +VD +EE + LLV +K C Sbjct: 191 LYTPEERDPVPLSIHHMPICVSFAFFQQGTYLLVDPNEREERV-MDGLLVIAMNKHREIC 249 >6H25-A nrPDB Length = 443 Score = 89.4 bits (220), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 74/240 (30%), Positives = 115/240 (47%), Gaps = 10/240 (4%) Query: 1 MASVTLSEAEKVYIVHGVQEDLRVDGRGCEDYRCVEVETDVVSNTSGSARVKLGHTDILV 60 M LS E+ +++ ++E R+DGR DYR + + G V+LG T +L Sbjct: 5 MKETPLSNCERRFLLRAIEEKKRLDGRQTYDYRNIRIS---FGTDYGCCIVELGKTRVLG 61 Query: 61 GVKAEMGTPKLEKPNEGYLEFFVDCSASATPEFEGRGGDDLGTEIANTLYRIFNNKSSVD 120 V E+ +PKL + EG L F ++ S A P FE DL ++ + R N +D Sbjct: 62 QVSCELVSPKLNRATEGILFFNLELSQMAAPAFEPGRQSDLLVKLNRLMERCLRNSKCID 121 Query: 121 LKTLCISPREHCWVLYVDVLLLECGGNLFDAISIAVKAALFNTRIPRVRVLEDEEGSKDI 180 ++LC+ E W + VD+ LL GN+ DA SIA AL + R P V V +G + Sbjct: 122 TESLCVVAGEKVWQIRVDLHLLNHDGNIIDAASIAAIVALCHFRRPDVSV----QGDEVT 177 Query: 181 ELSDDPYDCIRLSVENVPCIVTLC--KIGYRHVVDATLQEEACSLASLLVSVTSKGVVTC 238 + + D + LS+ ++P V+ + G +VD +EE + LLV +K C Sbjct: 178 LYTPEERDPVPLSIHHMPICVSFAFFQQGTYLLVDPNEREERV-MDGLLVIAMNKHREIC 236 >4OO1-A nrPDB Length = 305 Score = 81.3 bits (199), Expect = 5e-16, Method: Compositional matrix adjust. Identities = 63/262 (24%), Positives = 115/262 (43%), Gaps = 26/262 (9%) Query: 4 VTLSEAEKVYIVHGVQEDLRVDGRGCEDYRCVEVETDVVSNTSGSARVKLGHTDILVGVK 63 + +S +E +I+ ++++ R+DGR + +R VE+ G VK+G+T + + Sbjct: 5 IEISASESKFILEALRQNYRLDGRSFDQFRDVEI---TFGKEFGDVSVKMGNTKVHCRIS 61 Query: 64 AEMGTPKLEKPNEGYLEFFVDCSASATPEFEGRGGDDLGTE---IANTLYRIFNNKSSVD 120 ++ P ++P EG + S A +FE G+ G + + + + ++D Sbjct: 62 CQIAQPYEDRPFEGLFVISTEISPMAGSQFEN--GNITGEDEVLCSRIIEKSVRRSGALD 119 Query: 121 LKTLCISPREHCWVLYVDVLLLECGGNLFDAISIAVKAALFNTRIPRVRVLEDEEGSKDI 180 ++ LCI CW + DV L+C G DA IAV A L + + P + V G + I Sbjct: 120 VEGLCIVAGSKCWAVRADVHFLDCDGGFIDASCIAVMAGLMHFKKPDITV----HGEQII 175 Query: 181 ELSDDPYDCIRLSVENVPCIVTLCKIGYR--------------HVVDATLQEEACSLASL 226 + + + L + ++P VT + ++DATL+EE L Sbjct: 176 VHPVNEREPVPLGILHIPICVTFSFFNPQDTEENIKGETNSEISIIDATLKEELLRDGVL 235 Query: 227 LVSVTSKGVVTCMRKVGKGSLD 248 V++ V + K G +D Sbjct: 236 TVTLNKNREVVQVSKAGGLPMD 257 >5K36-E nrPDB Length = 269 Score = 70.5 bits (171), Expect = 8e-13, Method: Compositional matrix adjust. Identities = 63/248 (25%), Positives = 127/248 (51%), Gaps = 26/248 (10%) Query: 4 VTLSEAEKVYIVHGVQE--DLRVDGRGCEDYRCVEVETDVVSNTSGSARVKLGH-TDILV 60 ++LS AEK Y+ + +R DGR +R +E+ TD + +++GS+R+ ++ +V Sbjct: 5 MSLSVAEKSYLYDSLASTPSIRPDGRLPHQFRPIEIFTDFLPSSNGSSRIIASDGSECIV 64 Query: 61 GVKAEMGTPKLEKPNEGYLEFFVDCSASATPEFEGRGGDDLGTE-IANTLYRIFNNKSSV 119 +K+++ +E NE L+ VD + G+ D L E I + L ++ + S V Sbjct: 65 SIKSKVVDHHVE--NE-LLQVDVDIA--------GQRDDALVVETITSLLNKVLKSGSGV 113 Query: 120 DLKTLCISPREHCWVLYVDVLLLECGGNLFDAISIAVKAALFNTRIPRVRVLEDEEGSKD 179 D L ++ +++ + ++VDVL++ + IS A+ +AL +T +P++ D D Sbjct: 114 DSSKLQLT-KKYSFKIFVDVLVISSHSHPVSLISFAIYSALNSTYLPKLISAFD-----D 167 Query: 180 IELSDDP----YDCIRLSVENVPCIVTLCKIGYRHVVDATLQEEACSLASLLVSVTSKGV 235 +E+ + P YD ++L + N P + L +G ++D E + L++S ++ + Sbjct: 168 LEVEELPTFHDYDMVKLDI-NPPLVFILAVVGNNMLLDPAANESEVANNGLIISWSNGKI 226 Query: 236 VTCMRKVG 243 + +R V Sbjct: 227 TSPIRSVA 234 >2PO0-A nrPDB Length = 249 Score = 40.4 bits (93), Expect = 0.001, Method: Compositional matrix adjust. Identities = 23/89 (25%), Positives = 43/89 (48%), Gaps = 2/89 (2%) Query: 23 RVDGRGCEDYRCVEVETDVVSNTSGSARVKLGHTDILVGVKA--EMGTPKLEKPNEGYLE 80 R+DGR + R +++E V+ N +GSA ++ G I+ V E+ L++P+ L Sbjct: 17 RIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAVYGPRELHPKHLQRPDRAILR 76 Query: 81 FFVDCSASATPEFEGRGGDDLGTEIANTL 109 + + + E + G D EI+ + Sbjct: 77 VRYNMAPFSVEERKKPGPDRRSIEISKVI 105 >2JEA-B nrPDB Length = 250 Score = 36.2 bits (82), Expect = 0.019, Method: Compositional matrix adjust. Identities = 34/146 (23%), Positives = 62/146 (42%), Gaps = 10/146 (6%) Query: 23 RVDGRGCEDYRCVEVETDVVSNTSGSARVKLGHTDILVGV--KAEMGTPKLEKPNEGYLE 80 R DGR ++ R +++E V+ N GSA ++G+T + V EM L P+ L Sbjct: 21 RTDGRKPDELRSIKIELGVLKNADGSAIFEMGNTKAIAAVYGPKEMHPRHLSLPDRAVLR 80 Query: 81 FFVDCSASATPEFEGRGGDDLGTEIANTLYRIFNNKSSVDLKTLCISPREHCWVLYVDVL 140 + +T E + E++ + + V+L PR V + ++L Sbjct: 81 VRYHMTPFSTDERKNPAPSRREIELSKVIREALESAVLVEL-----FPRTAIDV-FTEIL 134 Query: 141 LLECGGNLFDAISIAVKAALFNTRIP 166 + G L ++ ++ AL + IP Sbjct: 135 QADAGSRLVSLMAASL--ALADAGIP 158 >1E3H-A nrPDB Length = 757 Score = 35.4 bits (80), Expect = 0.028, Method: Compositional matrix adjust. Identities = 16/42 (38%), Positives = 22/42 (52%) Query: 18 VQEDLRVDGRGCEDYRCVEVETDVVSNTSGSARVKLGHTDIL 59 + E R+DGRG D R + E + + GSA + G T IL Sbjct: 351 IAEKKRIDGRGVTDIRTLAAEVEAIPRVHGSALFERGETQIL 392 >2WNR-B nrPDB Length = 240 Score = 35.0 bits (79), Expect = 0.038, Method: Compositional matrix adjust. Identities = 22/88 (25%), Positives = 42/88 (47%), Gaps = 2/88 (2%) Query: 22 LRVDGRGCEDYRCVEVETDVVSNTSGSARVKLGHTDILVGV--KAEMGTPKLEKPNEGYL 79 +R DGR ++ R +++E ++ GS+ ++ G ILV V E KL++P+ + Sbjct: 16 VREDGRAFDELRPLKIEAGILERADGSSYLEFGGNKILVAVYGPREAQIRKLQRPDRAVI 75 Query: 80 EFFVDCSASATPEFEGRGGDDLGTEIAN 107 + + + E + G D EI+ Sbjct: 76 RCRYNMAPFSVEERKRPGPDRRSVEISK 103 >3H1C-A nrPDB Length = 549 Score = 33.9 bits (76), Expect = 0.091, Method: Compositional matrix adjust. Identities = 25/76 (32%), Positives = 38/76 (50%), Gaps = 12/76 (15%) Query: 5 TLSEAEKVYIVHGVQEDL----------RVDGRGCEDYRCVEVETDVVSNTSGSARVKLG 54 TL E E I+H +++++ R+DGR + R ++V T V+ T GSA G Sbjct: 287 TLDENELGEILHAIEKNVVRSRVLAGEPRIDGREKDMIRGLDVRTGVLPRTHGSALFTRG 346 Query: 55 HTDILVGVKAEMGTPK 70 T L V A +GT + Sbjct: 347 ETQAL--VTATLGTAR 360 >3CDI-A nrPDB Length = 723 Score = 33.5 bits (75), Expect = 0.12, Method: Compositional matrix adjust. Identities = 25/76 (32%), Positives = 38/76 (50%), Gaps = 12/76 (15%) Query: 5 TLSEAEKVYIVHGVQEDL----------RVDGRGCEDYRCVEVETDVVSNTSGSARVKLG 54 TL E E I+H +++++ R+DGR + R ++V T V+ T GSA G Sbjct: 293 TLDENELGEILHAIEKNVVRSRVLAGEPRIDGREKDMIRGLDVRTGVLPRTHGSALFTRG 352 Query: 55 HTDILVGVKAEMGTPK 70 T L V A +GT + Sbjct: 353 ETQAL--VTATLGTAR 366 >3B4T-A nrPDB Length = 262 Score = 30.8 bits (68), Expect = 0.70, Method: Compositional matrix adjust. Identities = 16/51 (31%), Positives = 23/51 (45%) Query: 23 RVDGRGCEDYRCVEVETDVVSNTSGSARVKLGHTDILVGVKAEMGTPKLEK 73 R DGR + R V + N +GS ++ GHT +L G P+ K Sbjct: 7 REDGRLDHELRPVIITRGFTENPAGSVLIEFGHTKVLCTASVTEGVPRWRK 57 >5Y6T-A nrPDB Length = 387 Score = 30.0 bits (66), Expect = 1.1, Method: Compositional matrix adjust. Identities = 19/53 (35%), Positives = 26/53 (49%), Gaps = 10/53 (18%) Query: 57 DILVGVKAEMGTPKLEKPNEGYLEFFVDCSASATPEFEGRGGDDLGTEIANTL 109 D +V +KAE G L +V C TPEF+G G +GT+ NT+ Sbjct: 53 DYIVRIKAEGGNS---------LRIWVHCDGGYTPEFDGN-GYVVGTDAQNTM 95 >3HKM-A nrPDB Length = 246 Score = 30.0 bits (66), Expect = 1.1, Method: Compositional matrix adjust. Identities = 20/62 (32%), Positives = 27/62 (43%), Gaps = 1/62 (1%) Query: 20 EDLRVDGRGCEDYRCVEVETDVVSNTSGSARVKLGHTDILVGVKA-EMGTPKLEKPNEGY 78 E+ R DGR R + + GSAR G T +L V + GT K E P + Sbjct: 2 EESRADGRNPNQLRPFSCTRNPLDRAHGSARWAQGDTIVLAAVYGPKPGTRKGENPEKAS 61 Query: 79 LE 80 +E Sbjct: 62 IE 63 >6D6Q-B nrPDB Length = 249 Score = 30.0 bits (66), Expect = 1.3, Method: Compositional matrix adjust. Identities = 37/148 (25%), Positives = 57/148 (38%), Gaps = 12/148 (8%) Query: 23 RVDGRGCEDYRCVEVETDVVSNTSGSARVKLGHTDILV---GVKAEMGTPKLEKPNEGYL 79 RVDGR + R ++ V + GSA ++ G+T L G G+ P+ + Sbjct: 17 RVDGRRAGELRKIQARMGVFAQADGSAYIEQGNTKALAVVYGPHEIRGSRARALPDRALV 76 Query: 80 EFFVDCSASATPEFEGR-GGDDLGTEIANTLYRIFNNKSSVDLKTLCISPREHCWVLYVD 138 + +T E + R GD E+ L + F L PR + YV Sbjct: 77 NCQYSSATFSTGERKRRPHGDRKSCEMGLQLRQTFEAAILTQLH-----PRSQIDI-YVQ 130 Query: 139 VLLLECGGNLFDAISIAVKAALFNTRIP 166 V L+ G + A A A+ + IP Sbjct: 131 V--LQADGGTYAACVNAATLAVLDAGIP 156 >6D6K-A nrPDB Length = 705 Score = 29.3 bits (64), Expect = 2.2, Method: Compositional matrix adjust. Identities = 14/38 (36%), Positives = 20/38 (52%) Query: 23 RVDGRGCEDYRCVEVETDVVSNTSGSARVKLGHTDILV 60 R+DGR + R ++V+ V+ GSA G T LV Sbjct: 325 RIDGRDTKTVRALDVQVGVLERAHGSALFTRGETQALV 362 >3DD6-A nrPDB Length = 255 Score = 28.9 bits (63), Expect = 3.1, Method: Compositional matrix adjust. Identities = 13/48 (27%), Positives = 25/48 (52%) Query: 22 LRVDGRGCEDYRCVEVETDVVSNTSGSARVKLGHTDILVGVKAEMGTP 69 +RVDGR + R + + T+ + + GS +++G T ++ E P Sbjct: 11 MRVDGREKTELRHIHIHTNYLKHPEGSVLIEVGDTKVICSATIEERVP 58 >3LL3-A nrPDB Length = 504 Score = 28.5 bits (62), Expect = 3.3, Method: Compositional matrix adjust. Identities = 20/60 (33%), Positives = 28/60 (46%), Gaps = 6/60 (10%) Query: 228 VSVTSKGVVTCMRKVGKGSLDPESIFEMME------TGKRVGKVLHASLQSVVHKEESLG 281 V+ SKG KVG+ DP+ IF+ ++ T K GK+ S S +H LG Sbjct: 28 VASVSKGYPLIQTKVGQAEEDPKLIFDAVQEIIFDLTQKIDGKIAAISWSSQMHSLIGLG 87 >4BDV-A nrPDB Length = 760 Score = 28.5 bits (62), Expect = 3.9, Method: Compositional matrix adjust. Identities = 17/69 (24%), Positives = 33/69 (47%), Gaps = 5/69 (7%) Query: 166 PRVRVLEDEEGSK-DIELSDDPYDCIRLSVENVPCIVTLCKIGYRH----VVDATLQEEA 220 P++R+ +EE D +L+D D +R +N P + + + +H V +EE Sbjct: 333 PQLRMKNNEEAEDYDDDLTDSEMDVVRFDDDNSPSFIQIRSVAKKHPKTWVHYIAAEEED 392 Query: 221 CSLASLLVS 229 A L+++ Sbjct: 393 WDYAPLVLA 401 >4NBQ-A nrPDB Length = 715 Score = 28.1 bits (61), Expect = 4.6, Method: Compositional matrix adjust. Identities = 14/38 (36%), Positives = 20/38 (52%) Query: 23 RVDGRGCEDYRCVEVETDVVSNTSGSARVKLGHTDILV 60 R+DGR + R + V+ V+ + GSA G T LV Sbjct: 337 RIDGRDTKTVRPITVKVGVLPRSHGSALFTRGETQALV 374 >3U1K-A nrPDB Length = 630 Score = 28.1 bits (61), Expect = 4.8, Method: Compositional matrix adjust. Identities = 17/51 (33%), Positives = 24/51 (47%) Query: 9 AEKVYIVHGVQEDLRVDGRGCEDYRCVEVETDVVSNTSGSARVKLGHTDIL 59 A++V+ + E R DGR R V E D+ GSA + G T +L Sbjct: 305 AKEVFRSIVLNEYKRCDGRDLTSLRNVSCEVDMFKTLHGSALFQRGQTQVL 355 >1OYR-A nrPDB Length = 245 Score = 28.1 bits (61), Expect = 5.1, Method: Compositional matrix adjust. Identities = 13/48 (27%), Positives = 24/48 (50%) Query: 22 LRVDGRGCEDYRCVEVETDVVSNTSGSARVKLGHTDILVGVKAEMGTP 69 +R DGR ++ R + + D +S+ GS + G+T ++ E P Sbjct: 1 MRHDGRQHDELRPITFDLDFISHPEGSVLITAGNTKVICNASVEDRVP 48 >5MMM-c nrPDB Length = 218 Score = 27.7 bits (60), Expect = 5.4, Method: Compositional matrix adjust. Identities = 20/56 (35%), Positives = 30/56 (53%), Gaps = 5/56 (8%) Query: 17 GVQEDLRVDGRGC-EDYRCVEVETDVVSNTSGSARVKLGHTDILVGVKAEMGTPKL 71 G+QED ++ R C ++Y V+ T S G AR+++ L+ V MG PKL Sbjct: 32 GLQEDQKI--RDCIKNY--VQKNTKTSSGVEGIARIEIQKRIDLIQVIIHMGFPKL 83 >4AIM-A nrPDB Length = 726 Score = 27.7 bits (60), Expect = 5.8, Method: Compositional matrix adjust. Identities = 14/39 (35%), Positives = 20/39 (51%) Query: 22 LRVDGRGCEDYRCVEVETDVVSNTSGSARVKLGHTDILV 60 LR+DGR + R + E ++ T GSA G T +V Sbjct: 330 LRIDGRDVKTVRPILGEVGILPRTHGSALFTRGETQAIV 368 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 6D6Q-E nrPDB 373 e-104 6D6R-C nrPDB 296 9e-81 3L7Z-A nrPDB 278 1e-75 2NN6-A nrPDB 276 1e-74 2PO2-B nrPDB 274 3e-74 2WNR-A nrPDB 273 5e-74 4OO1-A nrPDB 272 2e-73 2BA1-H nrPDB 270 4e-73 6H25-A nrPDB 268 3e-72 5K36-E nrPDB 197 4e-51 2PO0-A nrPDB 106 1e-23 Sequences not found previously or not previously below threshold: 2WNR-B nrPDB 97 1e-20 2JEA-B nrPDB 96 2e-20 2BA0-F nrPDB 94 5e-20 1R6M-A nrPDB 89 2e-18 3B4T-A nrPDB 82 3e-16 1UDQ-A nrPDB 80 9e-16 3DD6-A nrPDB 80 9e-16 1OYR-A nrPDB 74 8e-14 6D6Q-B nrPDB 63 2e-10 3U1K-A nrPDB 56 3e-08 4OO1-B nrPDB 51 8e-07 4NBQ-A nrPDB 50 1e-06 3HKM-A nrPDB 48 4e-06 5YJJ-A nrPDB 48 4e-06 5XEX-A nrPDB 47 9e-06 4AIM-A nrPDB 47 1e-05 1E3H-A nrPDB 44 1e-04 6D6Q-F nrPDB 43 1e-04 3H1C-A nrPDB 42 4e-04 3CDI-A nrPDB 41 7e-04 4OO1-C nrPDB 38 0.004 6D6K-A nrPDB 37 0.009 6FSZ-DD nrPDB 35 0.037 6D6Q-D nrPDB 32 0.34 4DA9-A nrPDB 31 0.66 3NO6-A nrPDB 29 2.5 3OJO-A nrPDB 28 5.2 >6D6Q-E nrPDB Length = 293 Score = 373 bits (957), Expect = e-104, Method: Composition-based stats. Identities = 291/291 (100%), Positives = 291/291 (100%) Query: 1 MASVTLSEAEKVYIVHGVQEDLRVDGRGCEDYRCVEVETDVVSNTSGSARVKLGHTDILV 60 MASVTLSEAEKVYIVHGVQEDLRVDGRGCEDYRCVEVETDVVSNTSGSARVKLGHTDILV Sbjct: 3 MASVTLSEAEKVYIVHGVQEDLRVDGRGCEDYRCVEVETDVVSNTSGSARVKLGHTDILV 62 Query: 61 GVKAEMGTPKLEKPNEGYLEFFVDCSASATPEFEGRGGDDLGTEIANTLYRIFNNKSSVD 120 GVKAEMGTPKLEKPNEGYLEFFVDCSASATPEFEGRGGDDLGTEIANTLYRIFNNKSSVD Sbjct: 63 GVKAEMGTPKLEKPNEGYLEFFVDCSASATPEFEGRGGDDLGTEIANTLYRIFNNKSSVD 122 Query: 121 LKTLCISPREHCWVLYVDVLLLECGGNLFDAISIAVKAALFNTRIPRVRVLEDEEGSKDI 180 LKTLCISPREHCWVLYVDVLLLECGGNLFDAISIAVKAALFNTRIPRVRVLEDEEGSKDI Sbjct: 123 LKTLCISPREHCWVLYVDVLLLECGGNLFDAISIAVKAALFNTRIPRVRVLEDEEGSKDI 182 Query: 181 ELSDDPYDCIRLSVENVPCIVTLCKIGYRHVVDATLQEEACSLASLLVSVTSKGVVTCMR 240 ELSDDPYDCIRLSVENVPCIVTLCKIGYRHVVDATLQEEACSLASLLVSVTSKGVVTCMR Sbjct: 183 ELSDDPYDCIRLSVENVPCIVTLCKIGYRHVVDATLQEEACSLASLLVSVTSKGVVTCMR 242 Query: 241 KVGKGSLDPESIFEMMETGKRVGKVLHASLQSVVHKEESLGPKRQKVGFLG 291 KVGKGSLDPESIFEMMETGKRVGKVLHASLQSVVHKEESLGPKRQKVGFLG Sbjct: 243 KVGKGSLDPESIFEMMETGKRVGKVLHASLQSVVHKEESLGPKRQKVGFLG 293 >6D6R-C nrPDB Length = 278 Score = 296 bits (757), Expect = 9e-81, Method: Composition-based stats. Identities = 75/270 (27%), Positives = 126/270 (46%), Gaps = 10/270 (3%) Query: 12 VYIVHGVQEDLRVDGRGCEDYRCVEVETDVVSNTSGSARVKLGHTDILVGVKAEMGTPKL 71 Y ++E+ R DGR ++R V +S GSA VKLG+T ++ GVKAE P Sbjct: 14 EYYRRFLKENCRPDGRELGEFRTTTVNIGSISTADGSALVKLGNTTVICGVKAEFAAPST 73 Query: 72 EKPNEGYLEFFVDCSASATPEFEGRGGDDLGTEIANTLYRIFNNKSSVDLKTLCISPREH 131 + P++GY+ VD + F + + + + N + + LCISP + Sbjct: 74 DAPDKGYVVPNVDLPPLCSSRFRSGPPGEEAQVASQFIADVIENSQIIQKEDLCISPGKL 133 Query: 132 CWVLYVDVLLLECGGNLFDAISIAVKAALFNTRIPRVRVLEDEEGSKDIELSDDPYDCIR 191 WVLY D++ L+ GN+ DA + A+ AAL N ++P V + E E ++ L Y Sbjct: 134 VWVLYCDLICLDYDGNILDACTFALLAALKNVQLPEVTINE-ETALAEVNLKKKSY---- 188 Query: 192 LSVENVPCIVTLCKI-GYRHVVDATLQEEACSLASLLVSVTSKGVVTCMRKVGKGSLDPE 250 L++ P + +VD T +EE + +L + + +G + C+ K G L Sbjct: 189 LNIRTHPVATSFAVFDDTLLIVDPTGEEEHLATGTLTIVMDEEGKLCCLHKPGGSGLTGA 248 Query: 251 SIFEMMETG----KRVGKVLHASLQSVVHK 276 + + M K V K++ ++S+ K Sbjct: 249 KLQDCMSRAVTRHKEVKKLMDEVIKSMKPK 278 >3L7Z-A nrPDB Length = 271 Score = 278 bits (712), Expect = 1e-75, Method: Composition-based stats. Identities = 79/270 (29%), Positives = 130/270 (48%), Gaps = 12/270 (4%) Query: 3 SVTLSEAEKVYIVHGVQEDLRVDGRGCEDYRCVEVETDVVSNTSGSARVKLGHTDILVGV 62 + +K IV ++ +R DGR DYR + + D GSA VKLG T +L G Sbjct: 8 QNIIPIIKKESIVSLFEKGIRQDGRKLTDYRPLSITLDYAKKADGSALVKLGTTMVLAGT 67 Query: 63 KAEMGTPKLEKPNEGYLEFFVDCSASATPEFEGRGGDDLGTEIANTLYRIFNNKSSVDLK 122 K E+ P + PN+G L V+ A FE D+ E+A + R + ++DL Sbjct: 68 KLEIDKPYEDTPNQGNLIVNVELLPLAYTTFEPGPPDENAIELARVVDRSLRDSKALDLT 127 Query: 123 TLCISPREHCWVLYVDVLLLECGGNLFDAISIAVKAALFNTRIPRVRVLEDEEGSKDIEL 182 L I P + W +++DV +L+ GGN+ DA ++A AAL+NT++ +V ++ Sbjct: 128 KLVIEPGKSVWTVWLDVYVLDYGGNVLDACTLASVAALYNTKVYKVE-----------QI 176 Query: 183 SDDPYDCIRLSVENVPCI-VTLCKIGYRHVVDATLQEEACSLASLLVSVTSKGVVTCMRK 241 S + + + N P + +++ K+ VVD L EE+ A + S T + ++K Sbjct: 177 SVNKNEVVGKLPLNYPVVTISVAKVDKYLVVDPDLDEESIMDAKISFSYTPDLKIVGIQK 236 Query: 242 VGKGSLDPESIFEMMETGKRVGKVLHASLQ 271 GKGS+ + I + T + L L+ Sbjct: 237 SGKGSMSLQDIDQAENTARSTAVKLLEELK 266 >2NN6-A nrPDB Length = 358 Score = 276 bits (705), Expect = 1e-74, Method: Composition-based stats. Identities = 74/281 (26%), Positives = 131/281 (46%), Gaps = 10/281 (3%) Query: 1 MASVTLSEAEKVYIVHGVQEDLRVDGRGCEDYRCVEVETDVVSNTSGSARVKLGHTDILV 60 M LS E+ +++ ++E R+DGR DYR + + G V+LG T +L Sbjct: 18 MKETPLSNCERRFLLRAIEEKKRLDGRQTYDYRNIRIS---FGTDYGCCIVELGKTRVLG 74 Query: 61 GVKAEMGTPKLEKPNEGYLEFFVDCSASATPEFEGRGGDDLGTEIANTLYRIFNNKSSVD 120 V E+ +PKL + EG L F ++ S A P FE DL ++ + R N +D Sbjct: 75 QVSCELVSPKLNRATEGILFFNLELSQMAAPAFEPGRQSDLLVKLNRLMERCLRNSKCID 134 Query: 121 LKTLCISPREHCWVLYVDVLLLECGGNLFDAISIAVKAALFNTRIPRVRVLEDEEGSKDI 180 ++LC+ E W + VD+ LL GN+ DA SIA AL + R P V V +G + Sbjct: 135 TESLCVVAGEKVWQIRVDLHLLNHDGNIIDAASIAAIVALCHFRRPDVSV----QGDEVT 190 Query: 181 ELSDDPYDCIRLSVENVPCIVTLCKI--GYRHVVDATLQEEACSLASLLVSVTSKGVVTC 238 + + D + LS+ ++P V+ G +VD +EE L++++ + Sbjct: 191 LYTPEERDPVPLSIHHMPICVSFAFFQQGTYLLVDPNEREERVMDGLLVIAMNKHREICT 250 Query: 239 MRKVGKGSLDPESIFEMMETG-KRVGKVLHASLQSVVHKEE 278 ++ G L + + + +V ++ L+++ + ++ Sbjct: 251 IQSSGGIMLLKDQVLRCSKIAGVKVAEITELILKALENDQK 291 >2PO2-B nrPDB Length = 277 Score = 274 bits (701), Expect = 3e-74, Method: Composition-based stats. Identities = 87/275 (31%), Positives = 146/275 (53%), Gaps = 7/275 (2%) Query: 5 TLSEAEKVYIVHGVQEDLRVDGRGCEDYRCVEVETDVVSNTSGSARVKLGHTDILVGVKA 64 ++ + +I++ ++E R+D RG EDYR +E+E V+ GSA VKLG T +LVG+K Sbjct: 9 IVAGIMRDHIINLLKEGKRIDDRGFEDYRPIEIEVGVIEKAEGSALVKLGSTQVLVGIKT 68 Query: 65 EMGTPKLEKPNEGYLEFFVDCSASATPEFEGRGGDDLGTEIANTLYRIFNNKSSVDLKTL 124 +G P + PN G + V+ A+P FE D+ E+A + R +++L+ + Sbjct: 69 SLGEPFPDTPNMGVMTTNVELVPLASPTFEPGPPDERAIELARVIDRGIRESKALNLEKM 128 Query: 125 CISPREHCWVLYVDVLLLECGGNLFDAISIAVKAALFNTRIPRVRVLEDEEGSKDIELSD 184 I P + V+++DV +L+ GNL DAI IA AAL N R+P+VR E+ + ++ Sbjct: 129 VIVPGKIVRVVFIDVHVLDHDGNLMDAIGIAAIAALLNARVPKVRYNEETGEVETLD--- 185 Query: 185 DPYDCIRLSVENVPCIVTLCKIGYRHVVDATLQEEACSLASLLVSVTSKGVVTCMRKVGK 244 + L VE +P VT KIG VVD +L EE + ++ G ++ ++K Sbjct: 186 ---ETEPLPVEKIPVPVTFAKIGNILVVDPSLDEELVMDGKITITTDETGHISAVQKSEG 242 Query: 245 GSLDPESIFEMMETG-KRVGKVLHASLQSVVHKEE 278 G+ E + +ET K+ ++ L++V ++ Sbjct: 243 GAFKLEEVMYAVETAFKKAEEIRKLILEAVEKAKQ 277 >2WNR-A nrPDB Length = 271 Score = 273 bits (699), Expect = 5e-74, Method: Composition-based stats. Identities = 82/275 (29%), Positives = 139/275 (50%), Gaps = 8/275 (2%) Query: 2 ASVTLSEAEKVYIVHGVQEDLRVDGRGCEDYRCVEVETDVVSNTSGSARVKLGHTDILVG 61 + E + I + R+DGR ++R + +ET V+S GS+RVKLG+T I+VG Sbjct: 4 KMDIIPEITRKSITDLINNKERIDGRSLHEFRDISIETGVISKAEGSSRVKLGNTQIIVG 63 Query: 62 VKAEMGTPKLEKPNEGYLEFFVDCSASATPEFEGRGGDDLGTEIANTLYRIFNNKSSVDL 121 VK ++G P + P G + + A+P FE D+ E++ + R +DL Sbjct: 64 VKPQIGEPFPDTPEMGVILTNSELLPMASPTFEPGPPDERSVELSRVVDRCIRESRMIDL 123 Query: 122 KTLCISPREHCWVLYVDVLLLECGGNLFDAISIAVKAALFNTRIPRVRVLEDEEGSKDIE 181 + LCI W+L++D+ +++ GNLFDA +A AAL +TRIP V +D E Sbjct: 124 EKLCIIEGSKVWMLFLDLHIIDYDGNLFDAAVLATVAALLDTRIPAAEV-------EDGE 176 Query: 182 LSDDPYDCIRLSVENVPCIVTLCKIGYRHVVDATLQEEACSLASLLVSVTSKGVVTCMRK 241 + + L V + T KIG V+D +L+EE A + + VT +G + M+K Sbjct: 177 VVINREKMQPLPVNRKALMCTFAKIGNEIVLDPSLEEEDILTARISIGVTEEGSICAMQK 236 Query: 242 VGKGSLDPESIFEMMETG-KRVGKVLHASLQSVVH 275 G+G L + + + + ++V +++ +S+ Sbjct: 237 GGEGPLTRDDVLKAVSIAVEKVPQLIEYLDKSMTP 271 >4OO1-A nrPDB Length = 305 Score = 272 bits (695), Expect = 2e-73, Method: Composition-based stats. Identities = 68/301 (22%), Positives = 125/301 (41%), Gaps = 27/301 (8%) Query: 2 ASVTLSEAEKVYIVHGVQEDLRVDGRGCEDYRCVEVETDVVSNTSGSARVKLGHTDILVG 61 + +S +E +I+ ++++ R+DGR + +R VE+ G VK+G+T + Sbjct: 3 KDIEISASESKFILEALRQNYRLDGRSFDQFRDVEI---TFGKEFGDVSVKMGNTKVHCR 59 Query: 62 VKAEMGTPKLEKPNEGYLEFFVDCSASATPEFEGRG-GDDLGTEIANTLYRIFNNKSSVD 120 + ++ P ++P EG + S A +FE + + + + ++D Sbjct: 60 ISCQIAQPYEDRPFEGLFVISTEISPMAGSQFENGNITGEDEVLCSRIIEKSVRRSGALD 119 Query: 121 LKTLCISPREHCWVLYVDVLLLECGGNLFDAISIAVKAALFNTRIPRVRVLEDEEGSKDI 180 ++ LCI CW + DV L+C G DA IAV A L + + P + V G + I Sbjct: 120 VEGLCIVAGSKCWAVRADVHFLDCDGGFIDASCIAVMAGLMHFKKPDITV----HGEQII 175 Query: 181 ELSDDPYDCIRLSVENVPCIVTLCKIGYR--------------HVVDATLQEEACSLASL 226 + + + L + ++P VT + ++DATL+EE L Sbjct: 176 VHPVNEREPVPLGILHIPICVTFSFFNPQDTEENIKGETNSEISIIDATLKEELLRDGVL 235 Query: 227 LVSVTSKGVVTCMRKVGKGSLDPESIFEMMETGKR-VGKVLHASLQSVVHKEESLGPKRQ 285 V++ V + K G +D ++ + + K+ LQ + E KR Sbjct: 236 TVTLNKNREVVQVSKAGGLPMDALTLMKCCHEAYSIIEKITDQILQLLKEDSE----KRN 291 Query: 286 K 286 K Sbjct: 292 K 292 >2BA1-H nrPDB Length = 259 Score = 270 bits (691), Expect = 4e-73, Method: Composition-based stats. Identities = 78/273 (28%), Positives = 136/273 (49%), Gaps = 14/273 (5%) Query: 1 MASVTLSEAEKVYIVHGVQEDLRVDGRGCEDYRCVEVETDVVSNTSGSARVKLGHTDILV 60 M L + ++ Y++ ++++ R+DGRG +++R VE+ +V+ GSA VKLG T ++V Sbjct: 1 MPEDILVDIKRDYVLSKLRDNERIDGRGFDEFRKVEIIPNVIEKAEGSALVKLGDTQVVV 60 Query: 61 GVKAEMGTPKLEKPNEGYLEFFVDCSASATPEFEGRGGDDLGTEIANTLYRIFNNKSSVD 120 GVK + G P + P+ G + + A+P FE D+ E+A + R +VD Sbjct: 61 GVKMQPGEPYPDTPDRGVIIVNAELVPLASPTFEPGPPDENSIELARVVDRGIRESEAVD 120 Query: 121 LKTLCISPREHCWVLYVDVLLLECGGNLFDAISIAVKAALFNTRIPRVRVLEDEEGSKDI 180 L L I E W+++VD+ L+ GNL DA ++A AAL NT++P R E+ Sbjct: 121 LSKLVIEEGEKVWIVFVDIHALDDDGNLLDASALAAIAALMNTKVPAERFDLGED----- 175 Query: 181 ELSDDPYDCIRLSVENVPCIVTLCKIGYRHVVDATLQEEACSLASLLVSVTSKGVVTCMR 240 L V ++P VT +G +++VD + +E + +L ++ V M+ Sbjct: 176 ---------YLLPVRDLPVSVTSLIVGNKYLVDPSREEMSVGDTTLTITTDKDDNVVAMQ 226 Query: 241 KVGKGSLDPESIFEMMETGKRVGKVLHASLQSV 273 K G LD + E+++ + L + + Sbjct: 227 KSGGYLLDEKLFDELLDVSINCARKLREKFKEI 259 >6H25-A nrPDB Length = 443 Score = 268 bits (684), Expect = 3e-72, Method: Composition-based stats. Identities = 74/281 (26%), Positives = 131/281 (46%), Gaps = 10/281 (3%) Query: 1 MASVTLSEAEKVYIVHGVQEDLRVDGRGCEDYRCVEVETDVVSNTSGSARVKLGHTDILV 60 M LS E+ +++ ++E R+DGR DYR + + G V+LG T +L Sbjct: 5 MKETPLSNCERRFLLRAIEEKKRLDGRQTYDYRNIRIS---FGTDYGCCIVELGKTRVLG 61 Query: 61 GVKAEMGTPKLEKPNEGYLEFFVDCSASATPEFEGRGGDDLGTEIANTLYRIFNNKSSVD 120 V E+ +PKL + EG L F ++ S A P FE DL ++ + R N +D Sbjct: 62 QVSCELVSPKLNRATEGILFFNLELSQMAAPAFEPGRQSDLLVKLNRLMERCLRNSKCID 121 Query: 121 LKTLCISPREHCWVLYVDVLLLECGGNLFDAISIAVKAALFNTRIPRVRVLEDEEGSKDI 180 ++LC+ E W + VD+ LL GN+ DA SIA AL + R P V V +G + Sbjct: 122 TESLCVVAGEKVWQIRVDLHLLNHDGNIIDAASIAAIVALCHFRRPDVSV----QGDEVT 177 Query: 181 ELSDDPYDCIRLSVENVPCIVTLCKI--GYRHVVDATLQEEACSLASLLVSVTSKGVVTC 238 + + D + LS+ ++P V+ G +VD +EE L++++ + Sbjct: 178 LYTPEERDPVPLSIHHMPICVSFAFFQQGTYLLVDPNEREERVMDGLLVIAMNKHREICT 237 Query: 239 MRKVGKGSLDPESIFEMMETG-KRVGKVLHASLQSVVHKEE 278 ++ G L + + + +V ++ L+++ + ++ Sbjct: 238 IQSSGGIMLLKDQVLRCSKIAGVKVAEITELILKALENDQK 278 >5K36-E nrPDB Length = 269 Score = 197 bits (501), Expect = 4e-51, Method: Composition-based stats. Identities = 59/246 (23%), Positives = 124/246 (50%), Gaps = 18/246 (7%) Query: 2 ASVTLSEAEKVYIVHGVQE--DLRVDGRGCEDYRCVEVETDVVSNTSGSARVKLGH-TDI 58 ++LS AEK Y+ + +R DGR +R +E+ TD + +++GS+R+ ++ Sbjct: 3 PHMSLSVAEKSYLYDSLASTPSIRPDGRLPHQFRPIEIFTDFLPSSNGSSRIIASDGSEC 62 Query: 59 LVGVKAEMGTPKLEKPNEGYLEFFVDCSASATPEFEGRGGDDLGTE-IANTLYRIFNNKS 117 +V +K+++ +E L+ VD + G+ D L E I + L ++ + S Sbjct: 63 IVSIKSKVVDHHVENE---LLQVDVDIA--------GQRDDALVVETITSLLNKVLKSGS 111 Query: 118 SVDLKTLCISPREHCWVLYVDVLLLECGGNLFDAISIAVKAALFNTRIPRVRVLEDEEGS 177 VD L ++ +++ + ++VDVL++ + IS A+ +AL +T +P++ D+ Sbjct: 112 GVDSSKLQLT-KKYSFKIFVDVLVISSHSHPVSLISFAIYSALNSTYLPKLISAFDDLEV 170 Query: 178 KDIELSDDPYDCIRLSVENVPCIVTLCKIGYRHVVDATLQEEACSLASLLVSVTSKGVVT 237 +++ D YD ++L + N P + L +G ++D E + L++S ++ + + Sbjct: 171 EELPTFHD-YDMVKLDI-NPPLVFILAVVGNNMLLDPAANESEVANNGLIISWSNGKITS 228 Query: 238 CMRKVG 243 +R V Sbjct: 229 PIRSVA 234 >2PO0-A nrPDB Length = 249 Score = 106 bits (265), Expect = 1e-23, Method: Composition-based stats. Identities = 42/258 (16%), Positives = 94/258 (36%), Gaps = 42/258 (16%) Query: 19 QEDLRVDGRGCEDYRCVEVETDVVSNTSGSARVKLGHTDILVGVKA--EMGTPKLEKPNE 76 + R+DGR + R +++E V+ N +GSA ++ G I+ V E+ L++P+ Sbjct: 13 ENGRRIDGRKKYELRPIKMEVGVLKNANGSAYIEWGKNKIIAAVYGPRELHPKHLQRPDR 72 Query: 77 GYLEFFVDCSASATPEFEGRGGDDLGTEIANTLYRIFNNKSSVDLKTLCISPREHCWVLY 136 L + + + E + G D EI+ + ++ + PR ++ Sbjct: 73 AILRVRYNMAPFSVEERKKPGPDRRSIEISKVIKGALEPALILE-----MFPRTAI-DVF 126 Query: 137 VDVLLLECGGNL--FDAISIAVKAALFNTRIPRVRVLEDEEGSKDIELSDDPYDCIRLSV 194 ++VL + G + A S+A+ A + + Sbjct: 127 IEVLQADAGTRVAGITAASLALADA-------------------------------GIPM 155 Query: 195 ENVPCIVTLCKIGYRHVVDATLQEEACSLASLLVSVTSKGVVTCMRKVGKGSLDPESIFE 254 ++ KI V+D +E+ A + V++ + ++ L + E Sbjct: 156 RDLVAACAAGKIEGEIVLDLNKEEDNYGEADVPVAIMPLKNDITLLQMDGY-LTKDEFIE 214 Query: 255 MMETGKRVGKVLHASLQS 272 ++ + K ++ + Sbjct: 215 AVKLAIKGAKAVYQKQRE 232 >2WNR-B nrPDB Length = 240 Score = 96.7 bits (239), Expect = 1e-20, Method: Composition-based stats. Identities = 49/258 (18%), Positives = 97/258 (37%), Gaps = 38/258 (14%) Query: 21 DLRVDGRGCEDYRCVEVETDVVSNTSGSARVKLGHTDILVGVKA--EMGTPKLEKPNEGY 78 +R DGR ++ R +++E ++ GS+ ++ G ILV V E KL++P+ Sbjct: 15 SVREDGRAFDELRPLKIEAGILERADGSSYLEFGGNKILVAVYGPREAQIRKLQRPDRAV 74 Query: 79 LEFFVDCSASATPEFEGRGGDDLGTEIANTLYRIFNNKSSVDLKTLCISPREHCWVLYVD 138 + + + + E + G D EI+ ++ L+ PR V+ V Sbjct: 75 IRCRYNMAPFSVEERKRPGPDRRSVEISKITAEALR--PALILEKF---PRS---VIDVF 126 Query: 139 VLLLECGGNLFDAISIAVKAALFNTRIPRVRVLEDEEGSKDIELSDDPYDCIRLSVENVP 198 + +LE G A A AL + IP + ++ Sbjct: 127 IEVLEAEGGTRCAGITAASVALADAGIP---------------------------MRDMV 159 Query: 199 CIVTLCKIGYRHVVDATLQEEACSLASLLVSVTSKGVVTCMRKVGKGSLDPESIFEMMET 258 K+G + V+D + +E+ A + V++ + + + G+L PE ++ Sbjct: 160 VACAAGKVGDQVVLDLSEEEDKEGQADVPVAILPRTREITLLQS-DGNLTPEEFERALDL 218 Query: 259 GKRVGKVLHASLQSVVHK 276 +H + + K Sbjct: 219 AVEGCLRIHEVQKEALRK 236 >2JEA-B nrPDB Length = 250 Score = 96.0 bits (237), Expect = 2e-20, Method: Composition-based stats. Identities = 48/271 (17%), Positives = 99/271 (36%), Gaps = 44/271 (16%) Query: 18 VQEDLRVDGRGCEDYRCVEVETDVVSNTSGSARVKLGHTDILVGVKA--EMGTPKLEKPN 75 + + R DGR ++ R +++E V+ N GSA ++G+T + V EM L P+ Sbjct: 16 LDDGKRTDGRKPDELRSIKIELGVLKNADGSAIFEMGNTKAIAAVYGPKEMHPRHLSLPD 75 Query: 76 EGYLEFFVDCSASATPEFEGRGGDDLGTEIANTLYRIFNNKSSVDLKTLCISPREHCWVL 135 L + +T E + E++ + + V+L PR + Sbjct: 76 RAVLRVRYHMTPFSTDERKNPAPSRREIELSKVIREALESAVLVEL-----FPRTAI-DV 129 Query: 136 YVDVLLLECGGNLFDAISIAVKAALFNTRIPRVRVLEDEEGSKDIELSDDPYDCIRLSVE 195 + ++L + G L +A AL + IP + Sbjct: 130 FTEILQADAGSRLVSL--MAASLALADAGIP---------------------------MR 160 Query: 196 NVPCIVTLCKIGYRHVVDATLQEEACSLASLLVSVTSKGVVTCMRKVGKGSLDPESIFEM 255 ++ V + K ++D E A + +++ + ++ GS+ P+ + Sbjct: 161 DLIAGVAVGKADGVIILDLNETEAMWGEADMPIAMMPSLNQVTLFQL-NGSMTPDEFRQA 219 Query: 256 METGKR----VGKVLHASLQS--VVHKEESL 280 + + + + +L+S V KEE + Sbjct: 220 FDLAVKGINIIYNLEREALKSKYVEFKEEGV 250 >2BA0-F nrPDB Length = 258 Score = 94.4 bits (233), Expect = 5e-20, Method: Composition-based stats. Identities = 49/262 (18%), Positives = 102/262 (38%), Gaps = 24/262 (9%) Query: 16 HGVQEDLRVDGRGCEDYRCVEVETDVVSNTSGSARVKLGHTDILVGVKA--EMGTPKLEK 73 + + LR+DGR ++ R +++E V+ GS +++G ++ V E+ L+ Sbjct: 10 KLIVDGLRLDGRKFDELRPIKIEASVLKRADGSCYLEMGKNKVIAAVFGPREVHPRHLQD 69 Query: 74 PNEGYLEFFVDCSASATPEFEGRGGDDLGTEIANTLYRIFNNKSSVDLKTLCISPREHCW 133 P++ + + + + + E + G D EI+ F +V +K L PR Sbjct: 70 PSKAIIRYRYNMAPFSVEERKRPGPDRRSIEISKVSKEAFE---AVIMKEL--FPRSAI- 123 Query: 134 VLYVDVLLLECGGNLFDAISIAVKAALFNTRIP-RVRVLEDEEGSKDIELSDDP-YDCIR 191 ++V+V L+ A A AL + +P + + G D +L DP + Sbjct: 124 DIFVEV--LQADAGSRTACLNAASVALVDAGVPMKGMITSVAVGKADGQLVLDPMKEEDN 181 Query: 192 LSVENVPCIVTLCKIGYRHVVDATLQEEACSLASLLVSVTSKGVVTCMRKVGKGSLDPES 251 ++P + + E+ +L + +T V + KG+L Sbjct: 182 FGEADMPFAFLIR----------NGKIESIALLQMDGRMTRDEVKQAIELAKKGALQIYE 231 Query: 252 IFE--MMETGKRVGKVLHASLQ 271 + ++ VG+ + + Sbjct: 232 MQREAILRRYIEVGEEMDEITE 253 >1R6M-A nrPDB Length = 239 Score = 89.0 bits (219), Expect = 2e-18, Method: Composition-based stats. Identities = 45/246 (18%), Positives = 85/246 (34%), Gaps = 31/246 (12%) Query: 23 RVDGRGCEDYRCVEVETDVVSNTSGSARVKLGHTDILVGVKAEMGTP-KLEKPNEGYLEF 81 R GR + R + + + GS V+ G T ++ V AE G P L+ +G+L Sbjct: 3 RPSGRAADQLRPIRITRHYTKHAEGSVLVEFGDTKVICTVSAESGVPRFLKGQGQGWLTA 62 Query: 82 FVDCSASATPEFEG-----RGGDDLGTEIANTLYRIFNNKSSVDLKTLCISPREHCWVLY 136 +T E EI + R +++DL L E+ LY Sbjct: 63 EYGMLPRSTGERNQREASRGKQGGRTLEIQRLIGRSLR--AALDLSKL----GEN--TLY 114 Query: 137 VDVLLLECGGNLFDAISIAVKAALFNTRIPRVRVLEDEEGSKDIELSDDPYDCIRLSVEN 196 +D +++ G A AL + + + ++ Sbjct: 115 IDCDVIQADGGTRTASITGATVALIDA----------------LAVLKKRGALKGNPLKQ 158 Query: 197 VPCIVTLCKIGYRHVVDATLQEEACSLASLLVSVTSKGVVTCMRKVGKG-SLDPESIFEM 255 + V++ V+D E++ + L V +T G ++ +G P + M Sbjct: 159 MVAAVSVGIYQGVPVLDLDYLEDSAAETDLNVVMTDAGGFIEVQGTAEGAPFRPAELNAM 218 Query: 256 METGKR 261 +E ++ Sbjct: 219 LELAQQ 224 >3B4T-A nrPDB Length = 262 Score = 81.7 bits (200), Expect = 3e-16, Method: Composition-based stats. Identities = 48/246 (19%), Positives = 84/246 (34%), Gaps = 30/246 (12%) Query: 21 DLRVDGRGCEDYRCVEVETDVVSNTSGSARVKLGHTDILVGVKAEMGTPKLEKPN-EGYL 79 R DGR + R V + N +GS ++ GHT +L G P+ K G+L Sbjct: 5 SKREDGRLDHELRPVIITRGFTENPAGSVLIEFGHTKVLCTASVTEGVPRWRKATGLGWL 64 Query: 80 EFFVDCSASATPEFEG-----RGGDDLGTEIANTLYRIFNNKSSVDLKTLCISPREHCWV 134 SAT EI+ + R + +DL L E+ Sbjct: 65 TAEYAMLPSATHSRSDRESVRGRLSGRTQEISRLIGRSLR--ACIDLAAL----GENTIA 118 Query: 135 LYVDVLLLECGGNLFDAISIAVKAALFNTRIPRVRVLEDEEGSKDIELSDDPYDCIRLSV 194 + DV L+ G A AL + V L D + Sbjct: 119 IDCDV--LQADGGTRTAAITGAYVALAD----AVTYLSAAGKLSD-----------PRPL 161 Query: 195 ENVPCIVTLCKIGYRHVVDATLQEEACSLASLLVSVTSKGVVTCMRKVGKGS-LDPESIF 253 V++ + R VD +E++ + + V T G + ++ G+G+ ++ Sbjct: 162 SCAIAAVSVGVVDGRIRVDLPYEEDSRAEVDMNVVATDTGTLVEIQGTGEGATFARSTLD 221 Query: 254 EMMETG 259 ++++ Sbjct: 222 KLLDMA 227 >1UDQ-A nrPDB Length = 255 Score = 80.2 bits (196), Expect = 9e-16, Method: Composition-based stats. Identities = 40/246 (16%), Positives = 90/246 (36%), Gaps = 31/246 (12%) Query: 23 RVDGRGCEDYRCVEVETDVVSNTSGSARVKLGHTDILVGVKA-EMGTPKLEKPNEGYLEF 81 R DGR + R V ++ D + GS + G T ++ E L+ +G++ Sbjct: 2 RSDGRKEDQLRPVSIQRDFLEYPEGSCLISFGKTKVICTASVIENVPNWLKGKGQGWITA 61 Query: 82 FVDCSASATPEFE-----GRGGDDLGTEIANTLYRIFNNKSSVDLKTLCISPREHCWVLY 136 AT + EI + R ++V+L + E ++ Sbjct: 62 EYSMLPRATQQRTIRESVQGRIGGRTHEIQRMIGRAMR--TAVELTKI----GER--TIW 113 Query: 137 VDVLLLECGGNLFDAISIAVKAALFNTRIPRVRVLEDEEGSKDIELSDDPYDCIRLSVEN 196 VD +++ G A A+ + I IE + +++ Sbjct: 114 VDCDVIQADGGARTAAITGAFVAVADAII-------KLHKEGIIEET---------PIKD 157 Query: 197 VPCIVTLCKIGYRHVVDATLQEEACSLASLLVSVTSKGVVTCMRKVG-KGSLDPESIFEM 255 V++ + R ++D +E++ + + V T G ++ + +G + S + + +M Sbjct: 158 FVAAVSVGIVNDRILLDLNFEEDSAAQVDMNVVGTGSGRLSEVHTMGEEYSFTKDELIKM 217 Query: 256 METGKR 261 ++ ++ Sbjct: 218 LDLAQK 223 >3DD6-A nrPDB Length = 255 Score = 80.2 bits (196), Expect = 9e-16, Method: Composition-based stats. Identities = 43/267 (16%), Positives = 97/267 (36%), Gaps = 38/267 (14%) Query: 23 RVDGRGCEDYRCVEVETDVVSNTSGSARVKLGHTDILVGVKA-EMGTPKLEKPNEGYLEF 81 RVDGR + R + + T+ + + GS +++G T ++ E P + +G++ Sbjct: 12 RVDGREKTELRHIHIHTNYLKHPEGSVLIEVGDTKVICSATIEERVPPFMRGEGKGWVTA 71 Query: 82 FVDCSASATPEF-----EGRGGDDLGTEIANTLYRIFNNKSSVDLKTLCISPREHCWVLY 136 AT + EI + R + VDL+ L E ++ Sbjct: 72 EYAMIPRATEQRTIRESSKGKVTGRTMEIQRLIGRALR--AVVDLEAL----GER--TVW 123 Query: 137 VDVLLLECGGNLFDAISIAVKAALFNTRIPRVRVLEDEEGSKDIELSDDPYDCIRLSVEN 196 +D +++ G A A+ E ++ V++ Sbjct: 124 IDCDVIQADGGTRTASITGAYVAM----------------VLAFEKLLQAEKVSKIPVKD 167 Query: 197 VPCIVTLCKIGYR-HVVDATLQEEACSLASLLVSVTSKGVVTCMRKVG-KGSLDPESIFE 254 ++ + + V+D E++ + + V +T KG ++ G + + + E Sbjct: 168 YLAATSVGIVEEQGVVLDLNYAEDSKADVDMNVIMTGKGQFVEVQGTGEEATFSRAQLNE 227 Query: 255 MMETGKRVGKVLHASLQSVVHKEESLG 281 +++ ++ Q + ++E+LG Sbjct: 228 LLDAAEQ------GIFQLIDIQKEALG 248 >1OYR-A nrPDB Length = 245 Score = 74.0 bits (180), Expect = 8e-14, Method: Composition-based stats. Identities = 43/260 (16%), Positives = 85/260 (32%), Gaps = 45/260 (17%) Query: 23 RVDGRGCEDYRCVEVETDVVSNTSGSARVKLGHTDILVGVKAE-MGTPKLEKPNEGYLEF 81 R DGR ++ R + + D +S+ GS + G+T ++ E P L +G++ Sbjct: 2 RHDGRQHDELRPITFDLDFISHPEGSVLITAGNTKVICNASVEDRVPPFLRGGGKGWITA 61 Query: 82 FVDCSASATPEF-----EGRGGDDLGTEIANTLYRIFNNKSSVDLKTLCISPREHCWVLY 136 AT + EI + R + VDL+ L E ++ Sbjct: 62 EYSMLPRATNQRTIRESSKGKISGRTMEIQRLIGRALR--AVVDLEKL----GER--TIW 113 Query: 137 VDVLLLECGGNLFDAISIAVKAALFNTRIPRVRVLEDEEGSKDIELSDDPYDCIRLSVEN 196 +D +++ G TR + +L I+ + Sbjct: 114 IDCDVIQADGG---------------TRTASITGAFLAMAIAIGKLI--KAGTIKTNPIT 156 Query: 197 VPCIVTLCKIGYR--HVVDATLQEEACSLASLLVSVTSKGVVTCMRKVGK---------- 244 I ++D +E++ + + V +T G ++ G+ Sbjct: 157 DFLAAISVGIDKEQGILLDLNYEEDSSAEVDMNVIMTGSGRFVELQGTGEEATFSREDLN 216 Query: 245 --GSLDPESIFEMMETGKRV 262 L + I E+++ K V Sbjct: 217 GLLGLAEKGIQELIDKQKEV 236 >6D6Q-B nrPDB Length = 249 Score = 62.8 bits (151), Expect = 2e-10, Method: Composition-based stats. Identities = 47/265 (17%), Positives = 90/265 (33%), Gaps = 48/265 (18%) Query: 20 EDLRVDGRGCEDYRCVEVETDVVSNTSGSARVKLGHTDILVGVKAEMGTPKLEK------ 73 + RVDGR + R ++ V + GSA ++ G+T L V P + Sbjct: 14 QGYRVDGRRAGELRKIQARMGVFAQADGSAYIEQGNTKALAVVYG----PHEIRGSRARA 69 Query: 74 -PNEGYLEFFVDCSASATPEFEGRG-GDDLGTEIANTLYRIFNNKSSVDLKTLCISPREH 131 P+ + + +T E + R GD E+ L + F L PR Sbjct: 70 LPDRALVNCQYSSATFSTGERKRRPHGDRKSCEMGLQLRQTFEAAILTQLH-----PRS- 123 Query: 132 CWVLYVDVLLLECGGNLFDAISIAVKAALFNTRIPRVRVLEDEEGSKDIELSDDPYDCIR 191 + + V +L+ G + A A A+ + IP Sbjct: 124 --QIDIYVQVLQADGGTYAACVNAATLAVLDAGIP------------------------- 156 Query: 192 LSVENVPCIVTLCKIGYRHVVDATLQEEACSLASLLVSVTSKGVVTCMRKVGKGSLDPES 251 + + C + + + D + EEA L +++ + ++ L + Sbjct: 157 --MRDFVCACSAGFVDGTALADLSHVEEAAGGPQLALALLPASGQIALLEM-DARLHEDH 213 Query: 252 IFEMMETGKRVGKVLHASLQSVVHK 276 + ++E + + +H L VV + Sbjct: 214 LERVLEAAAQAARDVHTLLDRVVRQ 238 >3U1K-A nrPDB Length = 630 Score = 55.5 bits (132), Expect = 3e-08, Method: Composition-based stats. Identities = 51/295 (17%), Positives = 105/295 (35%), Gaps = 40/295 (13%) Query: 7 SEAEKVYIVHGVQEDLRVDGRGCEDYRCVEVETDVVSNTSGSARVKLGHTDILV------ 60 A++V+ + E R DGR R V E D+ GSA + G T +L Sbjct: 303 VVAKEVFRSIVLNEYKRCDGRDLTSLRNVSCEVDMFKTLHGSALFQRGQTQVLCTVTFDS 362 Query: 61 ---GVKAEMGTPKLEKPNEGYLEFFVDCSASATPEFEGRGGDDLGTEIANTLYRIFNNKS 117 G+K++ + + + AT E ++ R + + Sbjct: 363 LESGIKSDQVITAINGIKDKNFMLHYEFPPYATNEIG---------KVTGLNRRELGHGA 413 Query: 118 SVDLKTLCISPREHCWVLYVDVLLLECGGNLFDAISIAVKAALFNTRIPRVRVLEDEEGS 177 + + PR+ + + V +LE G+ A + AL ++ +P + G Sbjct: 414 LAEKALYPVIPRDFPFTIRVTSEVLESNGSSSMASACGGSLALMDSGVP---ISSAVAGV 470 Query: 178 KDIELSDDPYDCIRLSVENVPCIVTLCKIGYRHVVDATLQEEACSLASLLVSVTSKGVVT 237 ++ D + +E YR + D E+ ++ T+KG +T Sbjct: 471 AIGLVT--KTDPEKGEIE-----------DYRLLTDILGIEDYNGDMDFKIAGTNKG-IT 516 Query: 238 CMR---KVGKGSLD--PESIFEMMETGKRVGKVLHASLQSVVHKEESLGPKRQKV 287 ++ K+ + E+I + K + ++++ ++ + GP + V Sbjct: 517 ALQADIKLPGIPIKIVMEAIQQASVAKKEILQIMNKTISKPRASRKENGPVVETV 571 Score = 34.7 bits (78), Expect = 0.042, Method: Composition-based stats. Identities = 44/238 (18%), Positives = 76/238 (31%), Gaps = 50/238 (21%) Query: 33 RCVEVETDVVSN-TSGSARVKLGHTDILV-GVKAEMGTPKLEKPNEGYLEFFVDCSASAT 90 R +E+ + ++ GSA V+ G T ++V V +P P L A+A Sbjct: 15 RKLEISSGKLARFADGSAVVQSGDTAVMVTAVSKTKPSPSQFMP----LVVDYRQKAAAA 70 Query: 91 PE------FEGRGGDDLGTEIANTLYRIFNNKSSVDLKTLCISPREHCWVLYVDVLLLEC 144 G D + + R L Sbjct: 71 GRIPTNYLRREVGTSDKEILTSRIIDRSIRP--------------------------LFP 104 Query: 145 GGNLFDAISIAVKAALFNTRIPRVRVLEDEEGSKDIELSDDPYDCIRLSVENVPC-IVTL 203 G +D + A+ P V L S + LSD P+ N P V + Sbjct: 105 AGYFYDTQVLCNLLAVDGVNEPDV--LAINGASVALSLSDIPW--------NGPVGAVRI 154 Query: 204 CKIGYRHVVDATLQEEACSLASLLVSVTSKGVVTCMRKVGKGSLDPESIFEMMETGKR 261 I +VV+ T +E + S +L+V+ K + + + L + ++ G + Sbjct: 155 GIIDGEYVVNPTRKEMSSSTLNLVVAGAPKSQIVMLEASAENILQ-QDFCHAIKVGVK 211 >4OO1-B nrPDB Length = 250 Score = 50.5 bits (119), Expect = 8e-07, Method: Composition-based stats. Identities = 35/150 (23%), Positives = 64/150 (42%), Gaps = 19/150 (12%) Query: 20 EDLRVDGRGCEDYRCVEVETDVVS-NTSGSARVKLGHTDILVGVKAEMGTPKLEK---PN 75 E LR+DGR + R E + GS+ ++ G+ I+ VK P+L+ + Sbjct: 14 EGLRLDGRRWNELRRFESSINTHPHAADGSSYMEQGNNKIITLVKG-PKEPRLKSQMDTS 72 Query: 76 EGYLEFFVDCSASATPEFEGR--GGDDLGTEIANTLYRIFNNKSSVDLKTLCISPREHCW 133 + L V+ + + E + EI +L R+F ++ I PR Sbjct: 73 KALLNVSVNITKFSKFERSKSSHKNERRVLEIQTSLVRMFEKNVMLN-----IYPRT--- 124 Query: 134 VLYVDVLLLECGGN----LFDAISIAVKAA 159 V+ +++ +LE G L + I++A+ A Sbjct: 125 VIDIEIHVLEQDGGIMGSLINGITLALIDA 154 >4NBQ-A nrPDB Length = 715 Score = 49.7 bits (117), Expect = 1e-06, Method: Composition-based stats. Identities = 41/292 (14%), Positives = 86/292 (29%), Gaps = 44/292 (15%) Query: 4 VTLSEAEKVYIVHGVQEDL-RVDGRGCEDYRCVEVETDVVSNTSGSARVKLGHTD--ILV 60 V E E+ + + R+DGR + R + V+ V+ + GSA G T ++ Sbjct: 317 VIFHELERRIVREQILTGQPRIDGRDTKTVRPITVKVGVLPRSHGSALFTRGETQALVVT 376 Query: 61 GVKAEMGTPKLEKPN---EGYLEFFVDCSASATPE--FEGRGGDDLGTEIANTLYRIFNN 115 + E ++ + + F + E F R Sbjct: 377 TLGTERDAQSIDDLDGDRQEEFIFHYNFPPFCVGEVGFMSG-PKRREIGHGRLAKRAV-- 433 Query: 116 KSSVDLKTLCISPREHCWVLYVDVLLLECGGNLFDAISIAVKAALFNTRIPRVRVLEDEE 175 + + + +V+ V +LE G+ A AL + +P Sbjct: 434 ------VPVVPTLDKFPYVIRVVSEILESNGSSSMASVCGSSLALMDAGVP---TKAPVA 484 Query: 176 GSKDIELSDDPYDCIRLSVENVPCIVTLCKIGYRHVVDATLQEEACSLASLLVSVTSKGV 235 G + ++ + + E+ V+ TS GV Sbjct: 485 GIAMGLIKENDKYAVLSDIL--------------------GDEDHLGDMDFKVAGTSNGV 524 Query: 236 VTCMRKVGKGSLDPESIFEMMETGKR----VGKVLHASLQSVVHKEESLGPK 283 + + E + + ++ K + +++ L + L P+ Sbjct: 525 TALQMDIKIEGITKEIMEQALDQAKEGRLHILSIMNKVLDKPRSQVSDLAPQ 576 Score = 28.9 bits (63), Expect = 2.7, Method: Composition-based stats. Identities = 18/97 (18%), Positives = 30/97 (30%), Gaps = 11/97 (11%) Query: 27 RGCEDYRCVEVETDV---VSNTSGSARVKLGHTDILVGVKAEMGTPKLEKPNEGYLEFFV 83 R Y EV + +G+ V++G T +LV V A+ E + L Sbjct: 24 RKTFQYGKHEVTFETGEMARQATGAVVVRMGDTVLLVSVVAK--KEAEEGRDFFPLTVNY 81 Query: 84 DCSASATPEFEGR------GGDDLGTEIANTLYRIFN 114 A + G + T + + R Sbjct: 82 QEKTYAAGKIPGGYFKREGRPTEKETLTSRLIDRPLR 118 >3HKM-A nrPDB Length = 246 Score = 48.2 bits (113), Expect = 4e-06, Method: Composition-based stats. Identities = 44/261 (16%), Positives = 82/261 (31%), Gaps = 32/261 (12%) Query: 20 EDLRVDGRGCEDYRCVEVETDVVSNTSGSARVKLGHTDILVGVKA-EMGTPKLEKPNEGY 78 E+ R DGR R + + GSAR G T +L V + GT K E P + Sbjct: 2 EESRADGRNPNQLRPFSCTRNPLDRAHGSARWAQGDTIVLAAVYGPKPGTRKGENPEKAS 61 Query: 79 LEFFVDCSASATPEFEGRGGDDLGTEIANTLYRIFNNKSSVDLKTLCISPREHCWVLYVD 138 +E + ++ + L+++C+ V Sbjct: 62 IEVVWK--PMTGQIGKQEKEYEMTLKRT--------------LQSICLLTVHPNTTTSVI 105 Query: 139 VLLLECGGNLFDAISIAVKAALFNTRIP--RVRVLEDEEGSKDIELSDDPYDCIRLSVEN 196 + ++ G+L A AAL IP + V +D E+ D +++ Sbjct: 106 LQVVGNDGSLLPCAINACCAALVFAGIPLKHLAVAIGCGVLEDGEVILDTNKAEEQQLKS 165 Query: 197 VPCIVTLCKIGYRHVVDATLQEEACSLASLLVSVTSKGVVTCMRKVGKGSLDPESIFEMM 256 +V + +EE + + G + E F + Sbjct: 166 FAHLVFPNSRKSASSKEPNQKEEDSERGLIT-------------SITHGVMSEEDYFSCI 212 Query: 257 ETGKRVGKVLHASLQSVVHKE 277 E G + +++ + K+ Sbjct: 213 ERGLAASSRISDFMRTTLQKQ 233 >5YJJ-A nrPDB Length = 713 Score = 48.2 bits (113), Expect = 4e-06, Method: Composition-based stats. Identities = 48/299 (16%), Positives = 88/299 (29%), Gaps = 55/299 (18%) Query: 5 TLSEAEKVYIVHGVQ-EDLRVDGRGCEDYRCVEVETDVVSNTSGSARVK----------- 52 L++ K + + E +R DGR ++ R +E E ++ GS Sbjct: 312 ILNDLIKEEVRRLIADEKIRPDGRKVDEIRPLESEVGLLPRAHGSGLFTRGQTQALSVLT 371 Query: 53 ---LGHTDILVGVKAEMGTPKLEKPNEGYLEFFVDCSASATPEFEGRGGDDLGTEIANTL 109 LG ++ G+ E+ + N + P G LG + Sbjct: 372 LGALGDYQLIDGLGPEVEKRFMHHYNFPNFSVG-ETGPVRAPGRREIGHGALGERALRYI 430 Query: 110 YRIFNNKSSVDLKTLCISPREHCWVLYVDVLLLECGGNLFDAISIAVKAALFNTRIPRVR 169 D + + + + +LE G+ A AL + +P Sbjct: 431 --------IPDTQDF-------PYTIRIVSEVLESNGSSSQASICGSTLALMDAGVP--- 472 Query: 170 VLEDEEGSKDIELSDDPYDCIRLSVENVPCIVTLCKIGYRHVVDATLQEEACSLASLLVS 229 I+ V + + Y + D E+A V+ Sbjct: 473 --------------------IKAPVAGIAMGLVTRDDSYTILTDIQGMEDALGDMDFKVA 512 Query: 230 VTSKGVVTCMRKVGKGSLDPESIFEMMETGKRVG-KVLHASLQSVVHKEESLGPKRQKV 287 T G+ + L E I E +E ++ ++ L ++ E L KV Sbjct: 513 GTKDGITAIQMDIKIDGLTREVIEEALEQARQGRLAIMDHMLHTIEQPREELSAYAPKV 571 Score = 34.3 bits (77), Expect = 0.056, Method: Composition-based stats. Identities = 15/89 (16%), Positives = 29/89 (32%), Gaps = 10/89 (11%) Query: 33 RCVEVETDVVSN-TSGSARVKLGHTDILVGVKAEMGTPKLEKPNEGYLEFFVDCSASATP 91 R + +ET ++ +G+ V+ G T +L + + + L + A Sbjct: 27 RSLTIETGQLAKQANGAVLVRYGDTVVL---STATASKEPRDGDFFPLTVNYEEKMYAAG 83 Query: 92 EFEGR------GGDDLGTEIANTLYRIFN 114 + G D T A + R Sbjct: 84 KIPGGFKKREGRPGDEATLTARLIDRPIR 112 >5XEX-A nrPDB Length = 559 Score = 47.0 bits (110), Expect = 9e-06, Method: Composition-based stats. Identities = 47/285 (16%), Positives = 87/285 (30%), Gaps = 44/285 (15%) Query: 5 TLSEAEKVYIVHGVQ-EDLRVDGRGCEDYRCVEVETDVVSNTSGSARVKLGHTDILVGVK 63 L+E K + + E +R DGR ++ R ++ E ++ T GS G T L + Sbjct: 300 ILNELVKEEVRRLIADEKIRPDGRKPDEIRPLDSEVGILPRTHGSGLFTRGQTQALSVLT 359 Query: 64 AEMGTPK-----LEKPNEGYLEFFVDCSASATPEFEGRG-GDDLGTEIANTLYRIFNNKS 117 L E + + E R Sbjct: 360 LGALGDYQLIDGLGPEEEKRFMHHYNFPNFSVGETGPVRAPGRREIGHGALGERALK--- 416 Query: 118 SVDLKTLCISP--REHCWVLYVDVLLLECGGNLFDAISIAVKAALFNTRIPRVRVLEDEE 175 I P + + + + +LE G+ A AL + +P Sbjct: 417 -------YIIPDTADFPYTIRIVSEVLESNGSSSQASICGSTLALMDAGVP--------- 460 Query: 176 GSKDIELSDDPYDCIRLSVENVPCIVTLCKIGYRHVVDATLQEEACSLASLLVSVTSKGV 235 I+ V + + + Y + D E+A V+ T +G+ Sbjct: 461 --------------IKAPVAGIAMGLVTREDSYTILTDIQGMEDALGDMDFKVAGTKEGI 506 Query: 236 VTCMRKVGKGSLDPESIFEMMETGKRVG-KVLHASLQSV-VHKEE 278 + L E I E +E +R ++++ LQ++ + E Sbjct: 507 TAIQMDIKIDGLTREIIEEALEQARRGRLEIMNHMLQTIDQPRTE 551 Score = 34.3 bits (77), Expect = 0.056, Method: Composition-based stats. Identities = 38/264 (14%), Positives = 80/264 (30%), Gaps = 51/264 (19%) Query: 33 RCVEVETDVVSN-TSGSARVKLGHTDILVGVKAEMGTPKLEKPNEGYLEFFVDCSASATP 91 R + +ET ++ +G+ V+ G T +L + + + L + A Sbjct: 15 RSLTIETGQLAKQANGAVLVRYGDTVVL---STATASKEPRDGDFFPLTVNYEEKMYAAG 71 Query: 92 EFEGR------GGDDLGTEIANTLYRIFNNKSSVDLKTLCISPREHCWVLYVDVLLLECG 145 + G D T A + R L +H + VL + Sbjct: 72 KIPGGFKKREGRPGDDATLTARLIDRPIR--------PLFPKGYKHDVQIMNMVLSADPD 123 Query: 146 GNLFDAISIAVKAALFNTRIPRVRVLEDEEGSKDIELSDDPYDCIRLSVENVPCIVTLCK 205 + A I AL + IP + V + Sbjct: 124 CSPQMAAMIGSSMALSVSDIP---------------------------FQGPIAGVNVGY 156 Query: 206 IGYRHVVDATLQEEACSLASLLVSVTSKGVVTCMRKVGKGSLDPESIFEMM----ETGKR 261 I +++++ T++E+ S L + V M + G + + + E + E +R Sbjct: 157 IDGKYIINPTVEEKEVS--RLDLEVAGHKDAVNMVEAGASEITEQEMLEAIFFGHEEIQR 214 Query: 262 VGKVLHASLQSVVHKEESLGPKRQ 285 + + + ++ P + Sbjct: 215 LVDFQQQIVDHIQPVKQEFIPAER 238 >4AIM-A nrPDB Length = 726 Score = 47.0 bits (110), Expect = 1e-05, Method: Composition-based stats. Identities = 41/282 (14%), Positives = 85/282 (30%), Gaps = 39/282 (13%) Query: 8 EAEKVYIVHG-VQEDLRVDGRGCEDYRCVEVETDVVSNTSGSARVKLGHTDILVGVKAEM 66 E E + G + LR+DGR + R + E ++ T GSA G T +V Sbjct: 315 ELEADVVRRGILDTGLRIDGRDVKTVRPILGEVGILPRTHGSALFTRGETQAIVVATLGT 374 Query: 67 GTPK-----LEKPNEGYLEFFVDCSASA-TPEFEGRGGDDLGTEIANTLYRIFNNKSSVD 120 G + LE + + + +R Sbjct: 375 GDDEQFIDALEGTYKESFLLHYNFPPYSVGETGRMGSPGRREIGHGKLAWRALR------ 428 Query: 121 LKTLCISPREHCWVLYVDVLLLECGGNLFDAISIAVKAALFNTRIPRVRVLEDEEGSKDI 180 + + + + + + + E G+ A A+ + +P VR Sbjct: 429 --PMLPTKEDFPYTIRLVSEITESNGSSSMATVCGSSLAMMDAGVPLVR----------- 475 Query: 181 ELSDDPYDCIRLSVENVPCIVTLCKIGYRHVVDATLQEEACSLASLLVSVTSKGVVTCMR 240 V + + L + G+ + D E+ V+ TS+G+ + Sbjct: 476 ------------PVSGIAMGLILEQDGFAVLSDILGDEDHLGDMDFKVAGTSEGLTSLQM 523 Query: 241 KVGKGSLDPESIFEMMETGKRV-GKVLHASLQSVVHKEESLG 281 + + P + + + K +L +++ +G Sbjct: 524 DIKIAGITPAIMEQALAQAKEGRAHILGEMNKAMDAPRADVG 565 >1E3H-A nrPDB Length = 757 Score = 43.6 bits (101), Expect = 1e-04, Method: Composition-based stats. Identities = 19/104 (18%), Positives = 29/104 (27%), Gaps = 6/104 (5%) Query: 16 HGVQEDLRVDGRGCEDYRCVEVETDVVSNTSGSARVKLGHTDILVGVKAEM--GTPKLEK 73 + E R+DGRG D R + E + + GSA + G T IL M +L+ Sbjct: 349 RVIAEKKRIDGRGVTDIRTLAAEVEAIPRVHGSALFERGETQILGVTTLNMLRMEQQLDT 408 Query: 74 ---PNEGYLEFFVDCSASA-TPEFEGRGGDDLGTEIANTLYRIF 113 + + R Sbjct: 409 LSPVTRKRYMHNYNFPPYSVGETGRVGSPKRREIGHGALAERAI 452 Score = 27.8 bits (60), Expect = 5.8, Method: Composition-based stats. Identities = 13/91 (14%), Positives = 27/91 (29%), Gaps = 8/91 (8%) Query: 33 RCVEVETDVVSN-TSGSARVKLGHTDILVGVKAEMGTPKLEKPNEGYLEFFVDCSASATP 91 R + ET ++ +GSA L +++ PK ++ + L V+ A Sbjct: 37 RTIRFETGRLARQAAGSAVAYLDDDTMVLSATTASKNPK-DQLDFFPLTVDVEERMYAAG 95 Query: 92 E------FEGRGGDDLGTEIANTLYRIFNNK 116 + + + R Sbjct: 96 KIPGSFFRREGRPSEDAILTCRLIDRPLRPS 126 >6D6Q-F nrPDB Length = 272 Score = 43.2 bits (100), Expect = 1e-04, Method: Composition-based stats. Identities = 46/275 (16%), Positives = 73/275 (26%), Gaps = 53/275 (19%) Query: 15 VHGVQEDLRVDGRGCEDYRCVEVETDVVSNTSGSARVKLGHTDILVGVKA---------- 64 ++ E+ R R V ++S GSA ++ G T +L V Sbjct: 19 LYAADEEEAPGTRDPTRLRPVYARAGLLSQAKGSAYLEAGGTKVLCAVSGPRQAEGGERG 78 Query: 65 ---EMGTPKLEKPNEGYLEFFVDCSASATPEFEGRGGDDLGTEIANTLYRIFNNKSSVDL 121 + G L + A G E+A L Sbjct: 79 GGPAGAGGEAPAALRGRLLCDFRRAPFAGRRRRAPPGGCEERELALALQEALEPA----- 133 Query: 122 KTLCISPREHCW-VLYVDVLLLECGGNLFDAISIAVKAALFNTRIPRVRVLEDEEGSKDI 180 + + L V LLLE GG+ + Sbjct: 134 ----VRLGRYPRAQLEVSALLLEDGGS-------------------ALAAALTAAALALA 170 Query: 181 ELSDDPYDCI---RLSVENVPCIVTLCKIGYRHVVDATLQEEACSLASLLVSVTSKGVVT 237 + + YD + LS+ P ++D T EE + A L V++ Sbjct: 171 DAGVEMYDLVVGCGLSLAPGPAPT--------WLLDPTRLEEERAAAGLTVALMPVLNQV 222 Query: 238 CMRKVGKGSLDPESIFEMMETGKRVGKVLHASLQS 272 ES E + G + L+ LQ Sbjct: 223 AGLLGSGEGGLTESWAEAVRLGLEGCQRLYPVLQQ 257 >3H1C-A nrPDB Length = 549 Score = 41.7 bits (96), Expect = 4e-04, Method: Composition-based stats. Identities = 32/176 (18%), Positives = 53/176 (30%), Gaps = 29/176 (16%) Query: 5 TLSEAEKVYIV-HGVQEDLRVDGRGCEDYRCVEVETDVVSNTSGSARVKLGHTDILV--- 60 L EK + + + R+DGR + R ++V T V+ T GSA G T LV Sbjct: 296 ILHAIEKNVVRSRVLAGEPRIDGREKDMIRGLDVRTGVLPRTHGSALFTRGETQALVTAT 355 Query: 61 -------GVKAEMGTPKLEKPNEGYLEFFVDCSASA-TPEFEGRGGDDLGTEIANTLYRI 112 V E+ + + F + + R Sbjct: 356 LGTARDAQVLDELMGERTDT-----FLFHYNFPPYSVGETGMVGSPKRREIGHGRLAKRG 410 Query: 113 FNNKSSVDLKTLCISP--REHCWVLYVDVLLLECGGNLFDAISIAVKAALFNTRIP 166 L + P + + + V + E G+ A AL + +P Sbjct: 411 V----------LAVMPDMDKFPYTVRVVSEITESNGSSSMASVCGASLALMDAGVP 456 >3CDI-A nrPDB Length = 723 Score = 40.9 bits (94), Expect = 7e-04, Method: Composition-based stats. Identities = 32/176 (18%), Positives = 53/176 (30%), Gaps = 29/176 (16%) Query: 5 TLSEAEKVYIV-HGVQEDLRVDGRGCEDYRCVEVETDVVSNTSGSARVKLGHTDILV--- 60 L EK + + + R+DGR + R ++V T V+ T GSA G T LV Sbjct: 302 ILHAIEKNVVRSRVLAGEPRIDGREKDMIRGLDVRTGVLPRTHGSALFTRGETQALVTAT 361 Query: 61 -------GVKAEMGTPKLEKPNEGYLEFFVDCSASA-TPEFEGRGGDDLGTEIANTLYRI 112 V E+ + + F + + R Sbjct: 362 LGTARDAQVLDELMGERTDT-----FLFHYNFPPYSVGETGMVGSPKRREIGHGRLAKRG 416 Query: 113 FNNKSSVDLKTLCISP--REHCWVLYVDVLLLECGGNLFDAISIAVKAALFNTRIP 166 L + P + + + V + E G+ A AL + +P Sbjct: 417 V----------LAVMPDMDKFPYTVRVVSEITESNGSSSMASVCGASLALMDAGVP 462 >4OO1-C nrPDB Length = 394 Score = 38.2 bits (87), Expect = 0.004, Method: Composition-based stats. Identities = 43/328 (13%), Positives = 93/328 (28%), Gaps = 87/328 (26%) Query: 2 ASVTLSEAEKVYIVHGVQEDLRVDGRGCEDYRCVEVETDVVS------------NTSGSA 49 V + ++ + + +R R E++R V +E + +S N GS Sbjct: 19 PEVLARISPELSLQRHLSLGIRPCLRKYEEFRDVAIENNTLSRYADAGNIDTKNNILGSN 78 Query: 50 RVKLGHTDILVGVKAEMGTP----------------KLEKPNEGYLEFFVDCSASATPEF 93 +K G T ++ + + E + + E Sbjct: 79 VLKSGKTIVITSITGGIIEETSAAIKDLDDFGEEELFEVTKEEDIIANYASVYPVVEVER 138 Query: 94 -EGRGGDDLGTEIANTLYRIFNNKSSVDLKTLCISPR----------------------- 129 D I+ L+ + + K L + Sbjct: 139 GRVGACTDEEMTISQKLHDSILHSRILPKKALKVKAGVRSANEDGTFSVLYPDELEDDTL 198 Query: 130 ---------EHCWVLYVDVLLLECGGNLFDAISIAVKAALFNTRIPRVRVLEDEEGSKDI 180 + +VLY +++L G +FD ++ AL + ++PR + E + Sbjct: 199 NETNLKMKRKWSYVLYAKIVVLSRTGPVFDLCWNSLMYALQSVKLPRAFIDERASDLRMT 258 Query: 181 E-------LSDDPYDCIRLSVENVPCIV---TLCKIGYRHVV--DA--------TLQEEA 220 + Y+ I ++VP ++ + +V D +EE Sbjct: 259 IRTRGRSATIRETYEIICDQTKSVPLMINAKNIAFASNYGIVELDPECQLQNSDNSEEEE 318 Query: 221 C------SLASLLVSVTSKGVVTCMRKV 242 L+ + ++ T + Sbjct: 319 VDIDMDKLNTVLIADLDTEAEETSIHST 346 >6D6K-A nrPDB Length = 705 Score = 37.0 bits (84), Expect = 0.009, Method: Composition-based stats. Identities = 14/45 (31%), Positives = 22/45 (48%) Query: 16 HGVQEDLRVDGRGCEDYRCVEVETDVVSNTSGSARVKLGHTDILV 60 + + R+DGR + R ++V+ V+ GSA G T LV Sbjct: 318 NILSGKPRIDGRDTKTVRALDVQVGVLERAHGSALFTRGETQALV 362 >6FSZ-DD nrPDB Length = 245 Score = 35.1 bits (79), Expect = 0.037, Method: Composition-based stats. Identities = 31/204 (15%), Positives = 63/204 (30%), Gaps = 10/204 (4%) Query: 19 QEDLRVDGRGCEDYRCVEVETDVVSNTSGSARVKLGHTDILVGVKAEMGTP-KLEKPNEG 77 R+D + V+ E ++ + GS+ T ++ V + + E P + Sbjct: 9 NTKNRLDSAEKKKKMSVQAEIGILDHVDGSSEFVSQDTKVICSVTGPIEPKARQELPTQL 68 Query: 78 YLEFFVDCSASATPEFEGRGGDDLGTEIANTLYRIFNNKSSVDLKTLCISPREHCWVLYV 137 LE V + E D L + + R + + + E Sbjct: 69 ALEIIVRPAKGVATTREKVLEDKLRAVLTPLITRHCYPRQLCQITCQILESGED--EAEF 126 Query: 138 DVLLLECGGNLFDAISIAVKAA--LFNTRIPRVRVLEDEEGSKDIELSDDPYDCIRLSVE 195 + L C +A +A+ A N+ + + ++ S I I LSV Sbjct: 127 SLRELSC---CINAAFLALVDAGIALNSMCASIPIAIIKDTSDIIVDPTAEQLKISLSVH 183 Query: 196 NVPCIVTLC--KIGYRHVVDATLQ 217 + + ++D+ Sbjct: 184 TLALEFVNGGKVVKNVLLLDSNGD 207 >6D6Q-D nrPDB Length = 237 Score = 32.0 bits (71), Expect = 0.34, Method: Composition-based stats. Identities = 47/220 (21%), Positives = 71/220 (32%), Gaps = 43/220 (19%) Query: 32 YRCVEVETDVVSNTSGSARVKLGHTDILVGVKAEMGTPKLEKPNEGYLEFFVDCSASATP 91 R E +++S GSA G T +L GV P E ++ + AT Sbjct: 30 LRHFACEQNLLSRPDGSASFLQGDTSVLAGVYG---------PAE--VKVSKEIFNKATL 78 Query: 92 EFEGRGGDDLGTEIANTLYRIFNNK-SSVDLKTLCISPREHCWVLYVDVLLLECGGNLFD 150 E R L + R+ N +V L TL PR V+ + ++ G+L Sbjct: 79 EVILRPKIGLPGVAEKSRERLIRNTCEAVVLGTL--HPRTSITVV---LQVVSDAGSLLA 133 Query: 151 AISIAVKAALFNTRIPRVRVLEDEEGSKDIELSDDPYDCIRLSVENVPCIVTLCKIGYRH 210 A AL + +P +R L L G Sbjct: 134 CCLNAACMALVDAGVP-MRALFCG------------------------VACALDSDGT-L 167 Query: 211 VVDATLQEEACSLASLLVSVTSKGVVTCMRKVGKGSLDPE 250 V+D T ++E + A L ++ S M D E Sbjct: 168 VLDPTSKQEKEARAVLTFALDSVERKLLMSSTKGLYSDTE 207 >4DA9-A nrPDB Length = 280 Score = 30.9 bits (68), Expect = 0.66, Method: Composition-based stats. Identities = 27/147 (18%), Positives = 46/147 (31%), Gaps = 8/147 (5%) Query: 129 REHCWVLYVDVLLLECGGNLFDAIS--IAVKAALFNTRIPRVRVLEDEEGSKDIELSDDP 186 L D+ L DA+ L N V +D ++L + Sbjct: 78 GARVIFLRADLADLSSHQATVDAVVAEFGRIDCLVNNAGIASIVRDDF-----LDLKPEN 132 Query: 187 YDCIRLSVENVPCIVTLCKIGYRHVVDATLQEEACSLASLL-VSVTSKGVVTCMRKVGKG 245 +D I T + DA ++ S+ V + + + CM K G Sbjct: 133 FDTIVGVNLRGTVFFTQAVLKAMLASDARASRSIINITSVSAVMTSPERLDYCMSKAGLA 192 Query: 246 SLDPESIFEMMETGKRVGKVLHASLQS 272 + + ETG V +V ++S Sbjct: 193 AFSQGLALRLAETGIAVFEVRPGIIRS 219 >3NO6-A nrPDB Length = 248 Score = 28.9 bits (63), Expect = 2.5, Method: Composition-based stats. Identities = 11/76 (14%), Positives = 23/76 (30%), Gaps = 13/76 (17%) Query: 198 PCIVTLCKIGYRHVVDATLQEEACSLASLLVSVTSKGVVTCMRKVGKGSLDPESIFEMME 257 PC IG R + D L +E+ + T + + ++M+ Sbjct: 155 PCPYVYAVIGKRAMEDPKLNKESVTSKWFQFYSTEMDELVDV------------FDQLMD 202 Query: 258 T-GKRVGKVLHASLQS 272 K + ++ Sbjct: 203 RLTKHCSETEKKEIKE 218 >3OJO-A nrPDB Length = 431 Score = 27.8 bits (60), Expect = 5.2, Method: Composition-based stats. Identities = 34/168 (20%), Positives = 57/168 (33%), Gaps = 32/168 (19%) Query: 107 NTLYRIFNNKSSVD-LKTLCISPREHCWVLYVDVLLLECGG----------NLFDAISIA 155 L + +N + + CI + + +V ++E N + ++IA Sbjct: 168 KILEELVHNNRIIGGVTKACIEAGKRVYRTFVQGEMIETDARTAEMSKLMENTYRDVNIA 227 Query: 156 VKAAL----------------FNTRIPRVRVLEDEEGSKDIELSDDPYDCIRLSVENVPC 199 + L + PRV + + G L+ DPY I EN Sbjct: 228 LANELTKICNNLNINVLDVIEMANKHPRVNIHQPGPGVGGHCLAVDPYFIIAKDPENAKL 287 Query: 200 IVTLCKIGYRH---VVDATLQ--EEACSLASLLVSVTSKGVVTCMRKV 242 I T +I VVD T Q + + +T KG V +R+ Sbjct: 288 IQTGREINNSMPAYVVDTTKQIIKALSGNKVTVFGLTYKGDVDDIRES 335 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.311 0.128 0.299 Lambda K H 0.267 0.0392 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 8,921,787 Number of Sequences: 36641 Number of extensions: 312683 Number of successful extensions: 945 Number of sequences better than 10.0: 39 Number of HSP's better than 10.0 without gapping: 59 Number of HSP's successfully gapped in prelim test: 11 Number of HSP's that attempted gapping in prelim test: 835 Number of HSP's gapped (non-prelim): 85 length of query: 291 length of database: 10,336,785 effective HSP length: 96 effective length of query: 195 effective length of database: 6,819,249 effective search space: 1329753555 effective search space used: 1329753555 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 58 (27.0 bits)