BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q14749 (295 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 1R74-A nrPDB 615 e-176 1D2C-A nrPDB 567 e-162 5H02-A nrPDB 104 4e-23 3D2L-A nrPDB 44 7e-05 2AVN-A nrPDB 42 3e-04 5BSZ-A nrPDB 40 0.001 4QTT-B nrPDB 39 0.003 6M83-A nrPDB 36 0.023 2IW1-A nrPDB 35 0.053 3SM3-A nrPDB 35 0.056 3JWJ-A nrPDB 34 0.062 6G4W-q nrPDB 34 0.067 5U19-A nrPDB 34 0.067 4KDR-A nrPDB 34 0.072 6MRO-A nrPDB 34 0.073 4KDC-A nrPDB 34 0.081 3BUS-A nrPDB 33 0.14 1VBF-A nrPDB 32 0.24 4NEC-A nrPDB 32 0.27 3CCF-A nrPDB 32 0.32 4FS8-A nrPDB 32 0.38 4QDJ-A nrPDB 32 0.42 4P7C-A nrPDB 31 0.55 4HTF-A nrPDB 30 1.1 3M70-A nrPDB 30 1.5 2I6G-A nrPDB 30 1.5 3L8D-A nrPDB 30 1.5 1VRM-A nrPDB 29 2.1 5EGS-A nrPDB 29 2.2 5F8E-A nrPDB 29 2.3 5WP4-A nrPDB 29 2.5 2ODR-C nrPDB 29 2.9 5WP5-A nrPDB 28 3.4 5GM1-A nrPDB 28 3.8 6H65-A nrPDB 28 4.0 1DUS-A nrPDB 28 5.6 5JMQ-A nrPDB 28 6.0 1Y8C-A nrPDB 28 6.0 1RI1-A nrPDB 28 6.1 6G8G-A nrPDB 28 6.8 3BXO-A nrPDB 27 7.8 5LV5-A nrPDB 27 8.2 6D05-C nrPDB 27 8.6 2VS1-A nrPDB 27 9.1 >1R74-A nrPDB Length = 294 Score = 615 bits (1585), Expect = e-176, Method: Compositional matrix adjust. Identities = 294/294 (100%), Positives = 294/294 (100%) Query: 2 VDSVYRTRSLGVAAEGLPDQYADGEAARVWQLYIGDTRSRTAEYKAWLLGLLRQHGCQRV 61 VDSVYRTRSLGVAAEGLPDQYADGEAARVWQLYIGDTRSRTAEYKAWLLGLLRQHGCQRV Sbjct: 1 VDSVYRTRSLGVAAEGLPDQYADGEAARVWQLYIGDTRSRTAEYKAWLLGLLRQHGCQRV 60 Query: 62 LDVACGTGVDSIMLVEEGFSVTSVDASDKMLKYALKERWNRRHEPAFDKWVIEEANWMTL 121 LDVACGTGVDSIMLVEEGFSVTSVDASDKMLKYALKERWNRRHEPAFDKWVIEEANWMTL Sbjct: 61 LDVACGTGVDSIMLVEEGFSVTSVDASDKMLKYALKERWNRRHEPAFDKWVIEEANWMTL 120 Query: 122 DKDVPQSAEGGFDAVICLGNSFAHLPDCKGDQSEHRLALKNIASMVRAGGLLVIDHRNYD 181 DKDVPQSAEGGFDAVICLGNSFAHLPDCKGDQSEHRLALKNIASMVRAGGLLVIDHRNYD Sbjct: 121 DKDVPQSAEGGFDAVICLGNSFAHLPDCKGDQSEHRLALKNIASMVRAGGLLVIDHRNYD 180 Query: 182 HILSTGCAPPGKNIYYKSDLTKDVTTSVLIVNNKAHMVTLDYTVQVPGAGQDGSPGLSKF 241 HILSTGCAPPGKNIYYKSDLTKDVTTSVLIVNNKAHMVTLDYTVQVPGAGQDGSPGLSKF Sbjct: 181 HILSTGCAPPGKNIYYKSDLTKDVTTSVLIVNNKAHMVTLDYTVQVPGAGQDGSPGLSKF 240 Query: 242 RLSYYPHCLASFTELLQAAFGGKCQHSVLGDFKPYKPGQTYIPCYFIHVLKRTD 295 RLSYYPHCLASFTELLQAAFGGKCQHSVLGDFKPYKPGQTYIPCYFIHVLKRTD Sbjct: 241 RLSYYPHCLASFTELLQAAFGGKCQHSVLGDFKPYKPGQTYIPCYFIHVLKRTD 294 >1D2C-A nrPDB Length = 292 Score = 567 bits (1462), Expect = e-162, Method: Compositional matrix adjust. Identities = 270/293 (92%), Positives = 281/293 (95%), Gaps = 2/293 (0%) Query: 2 VDSVYRTRSLGVAAEGLPDQYADGEAARVWQLYIGDTRSRTAEYKAWLLGLLRQHGCQRV 61 VDSVYRTRSLGVAAEG+PDQYADGEAARVWQLYIGDTRSRTAEYKAWLLGLLRQHGC RV Sbjct: 1 VDSVYRTRSLGVAAEGIPDQYADGEAARVWQLYIGDTRSRTAEYKAWLLGLLRQHGCHRV 60 Query: 62 LDVACGTGVDSIMLVEEGFSVTSVDASDKMLKYALKERWNRRHEPAFDKWVIEEANWMTL 121 LDVACGTGVDSIMLVEEGFSVTSVDASDKMLKYALKERWNRR EPAFDKWVIEEANW+TL Sbjct: 61 LDVACGTGVDSIMLVEEGFSVTSVDASDKMLKYALKERWNRRKEPAFDKWVIEEANWLTL 120 Query: 122 DKDVPQSAEGGFDAVICLGNSFAHLPDCKGDQSEHRLALKNIASMVRAGGLLVIDHRNYD 181 DKDVP A GFDAVICLGNSFAHLPD KGDQSEHRLALKNIASMVR GGLLVIDHRNYD Sbjct: 121 DKDVP--AGDGFDAVICLGNSFAHLPDSKGDQSEHRLALKNIASMVRPGGLLVIDHRNYD 178 Query: 182 HILSTGCAPPGKNIYYKSDLTKDVTTSVLIVNNKAHMVTLDYTVQVPGAGQDGSPGLSKF 241 +ILSTGCAPPGKNIYYKSDLTKD+TTSVL VNNKAHMVTLDYTVQVPGAG+DG+PG SKF Sbjct: 179 YILSTGCAPPGKNIYYKSDLTKDITTSVLTVNNKAHMVTLDYTVQVPGAGRDGAPGFSKF 238 Query: 242 RLSYYPHCLASFTELLQAAFGGKCQHSVLGDFKPYKPGQTYIPCYFIHVLKRT 294 RLSYYPHCLASFTEL+Q AFGG+CQHSVLGDFKPY+PGQ Y+PCYFIHVLK+T Sbjct: 239 RLSYYPHCLASFTELVQEAFGGRCQHSVLGDFKPYRPGQAYVPCYFIHVLKKT 291 >5H02-A nrPDB Length = 283 Score = 104 bits (260), Expect = 4e-23, Method: Compositional matrix adjust. Identities = 87/281 (30%), Positives = 136/281 (48%), Gaps = 37/281 (13%) Query: 15 AEGLPDQYADGEAARVWQLYIGDTRSRTAEYKAWLLGLLRQHGCQRVLDVACGTGVDSIM 74 ++G ++Y G + W I D SR ++ +L++ G ++VLDVA GTG +S+ Sbjct: 39 SDGYTNEYVSGFVDK-WDELI-DWESRAESEGDTIINILKERGVKKVLDVATGTGFNSVR 96 Query: 75 LVEEGFSVTSVDASDKMLKYALKERWNRRHEPAFDKWVIEEANWMTLDKDVPQSAEGGFD 134 L++ GF V S D S +ML A N R + V +A+W ++KD+ FD Sbjct: 97 LLQAGFDVVSADGSAEMLVKAFD---NARDHGYLMRTV--QADWRWMNKDIHDK----FD 147 Query: 135 AVICLGNSFAHLPDCKGDQSEHRLALKNIASMVRAGGLLVIDHRNYDHILSTGCAPPGKN 194 A++CLGNSF HL D+ + R AL ++++ G+L++D RNYD IL G + + Sbjct: 148 AIVCLGNSFTHLF----DEGDRRKALAEFYALLKHDGVLLLDQRNYDAILDDGYSSKHAH 203 Query: 195 IYYKSDLTKDVTTSVLIVNNKAHMVTLDYTVQVPGAGQDGSPGLSKFRLSYYPHCLASFT 254 YY D T SV + + Y DGS + L+ +P Sbjct: 204 -YYCGD-----TVSVYPEHVDEGLARFKYEF------SDGSV----YNLNMFPLRKDYTR 247 Query: 255 ELLQAAFGGKCQHSVLGDFKP-YKPGQTYIPCYFIHVLKRT 294 +LL G + + LGDFK YK + P +F+HV ++ Sbjct: 248 QLLHEV--GFQEINTLGDFKETYKEDE---PDFFLHVAEKN 283 >3D2L-A nrPDB Length = 243 Score = 44.3 bits (103), Expect = 7e-05, Method: Compositional matrix adjust. Identities = 38/145 (26%), Positives = 69/145 (47%), Gaps = 19/145 (13%) Query: 34 YIGDTRSRTAEYKAWLLGLLRQ-HGCQRVLDVACGTGVDSIMLVEEGFSVTSVDASDKML 92 Y+ D + Y W+ +L Q +R+ D+ CGTG +++L + + VT VD S++ML Sbjct: 9 YVYDELMQDVPYPEWVAWVLEQVEPGKRIADIGCGTGTATLLLADH-YEVTGVDLSEEML 67 Query: 93 KYAL-KERWNRRHEPAFDKWVIEEANWMTLDKDVPQSAEGGFDAVICLGNSFAHLPDCKG 151 + A K RH D WV + + ++P+ DA+ L +S +L Sbjct: 68 EIAQEKAMETNRH---VDFWVQD-----MRELELPEPV----DAITILCDSLNYL----Q 111 Query: 152 DQSEHRLALKNIASMVRAGGLLVID 176 +++ + + A ++ GG L+ D Sbjct: 112 TEADVKQTFDSAARLLTDGGKLLFD 136 >2AVN-A nrPDB Length = 260 Score = 42.0 bits (97), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 42/142 (29%), Positives = 64/142 (45%), Gaps = 25/142 (17%) Query: 29 RVWQLYIGDTRSRTAEYKA--W-----LLGLLRQHGCQ---RVLDVACGTGVDSIMLVEE 78 R W+ Y R+ + Y+ W L+G + + RVLD+ GTG S+ L E Sbjct: 16 RSWEFYDRIARAYDSMYETPKWKLYHRLIGSFLEEYLKNPCRVLDLGGGTGKWSLFLQER 75 Query: 79 GFSVTSVDASDKMLKYALKERWNRRHEPAFDKWVIEEANWMTLDKDVPQSAEGGFDAVIC 138 GF V VD S +ML+ A E V +A +D+P + G F+AV+ Sbjct: 76 GFEVVLVDPSKEMLEVA--------REKGVKNVVEAKA------EDLPFPS-GAFEAVLA 120 Query: 139 LGNSFAHLPDCKGDQSEHRLAL 160 LG+ +++ + SE R L Sbjct: 121 LGDVLSYVENKDKAFSEIRRVL 142 >5BSZ-A nrPDB Length = 250 Score = 40.0 bits (92), Expect = 0.001, Method: Compositional matrix adjust. Identities = 38/120 (31%), Positives = 53/120 (44%), Gaps = 19/120 (15%) Query: 57 GCQRVLDVACGTGVDSIMLVEEGFSVTSVDASDKMLKYALKERWNRRHEPAFDKWVIEEA 116 G + +LDVACGTG LVE V+ S M A E + +A Sbjct: 47 GARSLLDVACGTGEHLAHLVEHFPDAAGVELSPAMRAAA---------ERKLTATPVHQA 97 Query: 117 NWMTLDKDVPQSAEGGFDAVICLGNSFAHLPDCKGDQSEHRLALKNIASMVRAGGLLVID 176 + D D+ + FDAV CL S A+ D +E A++ +A + GG+LVID Sbjct: 98 D--MFDFDLGRV----FDAVCCLTGSIAY----AADTAELARAVRAMARHLPVGGVLVID 147 >4QTT-B nrPDB Length = 208 Score = 38.9 bits (89), Expect = 0.003, Method: Compositional matrix adjust. Identities = 28/78 (35%), Positives = 38/78 (48%), Gaps = 7/78 (8%) Query: 22 YADGEAARVWQLYIGDTRSRTAEYKAWL--LGLLRQHGCQRVLDVACGTGVDSIMLVEEG 79 Y D EA + Y G TR + + K L L LL C +LD+ CG+G+ +L +EG Sbjct: 14 YNDSEAHK----YTGSTRVQHIQAKMTLRALELLNLQPCSFILDIGCGSGLSGEILTQEG 69 Query: 80 FSV-TSVDASDKMLKYAL 96 V +D S ML L Sbjct: 70 DHVWCGLDISPSMLATGL 87 >6M83-A nrPDB Length = 263 Score = 35.8 bits (81), Expect = 0.023, Method: Compositional matrix adjust. Identities = 37/130 (28%), Positives = 57/130 (43%), Gaps = 21/130 (16%) Query: 49 LLGLLRQHG--CQRVLDVACGTGVDSIMLVEEGFSVTSVDASDKMLKYALKERWNRRHEP 106 L L+R+H +LDVACGTG+ L + +V ++ S ML A RR P Sbjct: 40 LAALVRRHSPKAASLLDVACGTGMHLRHLADSFGTVEGLELSADMLAIA------RRRNP 93 Query: 107 AFDKWVIEEANWMTLDKDVPQSAEGGFDAVICLGNSFAHLPDCKGDQSEHRLALKNIASM 166 V+ + S F AV C+ ++ HL Q+E AL+ A+ Sbjct: 94 ---DAVLHHGDMRDF------SLGRRFSAVTCMFSAIGHL----AGQAELDAALERFAAH 140 Query: 167 VRAGGLLVID 176 V G++V++ Sbjct: 141 VLPDGVVVVE 150 >2IW1-A nrPDB Length = 374 Score = 34.7 bits (78), Expect = 0.053, Method: Compositional matrix adjust. Identities = 25/89 (28%), Positives = 39/89 (43%), Gaps = 8/89 (8%) Query: 41 RTAEYKAWLLGLLRQHGCQRVLDVACGTGVDSIMLVEEGFSVTSVDASDKMLKYALKERW 100 R AEY AW+ L++H RV+ G+D + ++ A +K Y L R+ Sbjct: 64 RNAEYYAWVQNHLKEHPADRVVGFNKMPGLDVYFAADVCYAEKV--AQEKGFLYRLTSRY 121 Query: 101 NRRHEPAFDKWVIEEAN----WMTLDKDV 125 RH AF++ E+ M DK + Sbjct: 122 --RHYAAFERATFEQGKSTKLMMLTDKQI 148 >3SM3-A nrPDB Length = 235 Score = 34.7 bits (78), Expect = 0.056, Method: Compositional matrix adjust. Identities = 13/36 (36%), Positives = 24/36 (66%) Query: 60 RVLDVACGTGVDSIMLVEEGFSVTSVDASDKMLKYA 95 +LD+ CG+G S+ L +G+SVT +D + + ++ A Sbjct: 33 EILDIGCGSGKISLELASKGYSVTGIDINSEAIRLA 68 >3JWJ-A nrPDB Length = 202 Score = 34.3 bits (77), Expect = 0.062, Method: Compositional matrix adjust. Identities = 21/65 (32%), Positives = 38/65 (58%), Gaps = 4/65 (6%) Query: 49 LLGLLRQHGCQRVLDVACGTGVDSIMLVEEGF--SVTSVDASDKMLKYALKERWNRRHEP 106 ++ L+Q +RV+D+ CG G +L+++ F +T VD S + L+ A +ER +R P Sbjct: 11 VVAALKQSNARRVIDLGCGQGNLLKILLKDSFFEQITGVDVSYRSLEIA-QERLDRLRLP 69 Query: 107 AFDKW 111 ++W Sbjct: 70 R-NQW 73 >6G4W-q nrPDB Length = 281 Score = 34.3 bits (77), Expect = 0.067, Method: Compositional matrix adjust. Identities = 27/82 (32%), Positives = 38/82 (46%), Gaps = 3/82 (3%) Query: 17 GLPDQYADGEAAR--VWQLYIGDTRSRTAEYKAWLLGLLRQHGCQRVLDVACGTGVDSIM 74 G P+ + D AR V + D ++R A LL L C +LD+ CGTG+ Sbjct: 12 GPPELFYDETEARKYVRNSRMIDIQTRMAGRALELLYLPENKPCY-LLDIGCGTGLSGSY 70 Query: 75 LVEEGFSVTSVDASDKMLKYAL 96 L +EG +D S ML A+ Sbjct: 71 LSDEGHYWVGLDISPAMLDEAV 92 >5U19-A nrPDB Length = 341 Score = 34.3 bits (77), Expect = 0.067, Method: Compositional matrix adjust. Identities = 31/134 (23%), Positives = 59/134 (44%), Gaps = 19/134 (14%) Query: 49 LLGLLRQHGCQRVLDVACGTGVDSIMLVEEGFSVTSVDASDKMLKYALKERWNRRHEPAF 108 L+ L+ + G R LD+ CG+GV S++L + SV VD + + + + R A Sbjct: 135 LIRLMLRRGGARALDMGCGSGVLSLVLADRYESVLGVDVNPRAVALS-------RLNAAL 187 Query: 109 DKWVIEEANWMTLDKDVPQSAEGGFDAVIC------LGNSFAHLPDCKGDQSEHRLALKN 162 + N + D+ + AEG F ++ GN F L + + +N Sbjct: 188 NGLT----NVTFREGDMFEPAEGRFSRIVFNSPTNEEGNEFVDL--LEAGEPILETFFRN 241 Query: 163 IASMVRAGGLLVID 176 + + +GG++ ++ Sbjct: 242 VPRKLESGGIVEVN 255 >4KDR-A nrPDB Length = 223 Score = 34.3 bits (77), Expect = 0.072, Method: Compositional matrix adjust. Identities = 29/113 (25%), Positives = 54/113 (47%), Gaps = 17/113 (15%) Query: 59 QRVLDVACGTGVDSIMLVEEGFSVTSVDASDKMLKYALKERWNRRHEPAFDKWVIEEANW 118 ++VLDV CG G+ + + EG +VT +D + L+ A + H A + + + Sbjct: 64 KKVLDVGCGGGILAESMAREGATVTGLDMGFEPLQVA------KLH--ALESGIQVDYVQ 115 Query: 119 MTLDKDVPQSAEGGFDAVICLGNSFAHLPDCKGDQSEHRLALKNIASMVRAGG 171 T+++ + A G +D V C+ H+PD + ++ A +V+ GG Sbjct: 116 ETVEEHAAKHA-GQYDVVTCM-EMLEHVPDPQS-------VVRACAQLVKPGG 159 >6MRO-A nrPDB Length = 194 Score = 34.3 bits (77), Expect = 0.073, Method: Compositional matrix adjust. Identities = 17/45 (37%), Positives = 26/45 (57%), Gaps = 1/45 (2%) Query: 60 RVLDVACGTGVDSIMLVEEGFSVTSVDASDKMLKYALKERWNRRH 104 R LD+ CG G ++IML + G VT +D + + + A K + RH Sbjct: 35 RALDIGCGRGENAIMLAKNGCDVTGIDLAKRAISDA-KAKAIERH 78 >4KDC-A nrPDB Length = 246 Score = 33.9 bits (76), Expect = 0.081, Method: Compositional matrix adjust. Identities = 29/113 (25%), Positives = 54/113 (47%), Gaps = 17/113 (15%) Query: 59 QRVLDVACGTGVDSIMLVEEGFSVTSVDASDKMLKYALKERWNRRHEPAFDKWVIEEANW 118 ++VLDV CG G+ + + EG +VT +D + L+ A + H A + + + Sbjct: 64 KKVLDVGCGGGILAESMAREGATVTGLDMGFEPLQVA------KLH--ALESGIQVDYVQ 115 Query: 119 MTLDKDVPQSAEGGFDAVICLGNSFAHLPDCKGDQSEHRLALKNIASMVRAGG 171 T+++ + A G +D V C+ H+PD + ++ A +V+ GG Sbjct: 116 ETVEEHAAKHA-GQYDVVTCM-EMLEHVPDPQS-------VVRACAQLVKPGG 159 >3BUS-A nrPDB Length = 273 Score = 33.1 bits (74), Expect = 0.14, Method: Compositional matrix adjust. Identities = 38/130 (29%), Positives = 55/130 (42%), Gaps = 21/130 (16%) Query: 49 LLGLLRQHGCQRVLDVACGTGVDSIML-VEEGFSVTSVDASDKMLKYALKERWNRRHEPA 107 ++ LL RVLDV CG G ++ L VT + S + A N R A Sbjct: 53 MIALLDVRSGDRVLDVGCGIGKPAVRLATARDVRVTGISISRPQVNQA-----NARATAA 107 Query: 108 --FDKWVIEEANWMTLDKDVPQSAEGGFDAVICLGNSFAHLPDCKGDQSEHRLALKNIAS 165 ++ A+ M D+P + FDAV L S H+PD AL+ +A Sbjct: 108 GLANRVTFSYADAM----DLPFE-DASFDAVWAL-ESLHHMPD-------RGRALREMAR 154 Query: 166 MVRAGGLLVI 175 ++R GG + I Sbjct: 155 VLRPGGTVAI 164 >1VBF-A nrPDB Length = 231 Score = 32.3 bits (72), Expect = 0.24, Method: Compositional matrix adjust. Identities = 17/50 (34%), Positives = 28/50 (56%) Query: 48 WLLGLLRQHGCQRVLDVACGTGVDSIMLVEEGFSVTSVDASDKMLKYALK 97 ++L L H Q+VL++ G G + ++ E V SV+ ++KM YA K Sbjct: 61 FMLDELDLHKGQKVLEIGTGIGYYTALIAEIVDKVVSVEINEKMYNYASK 110 >4NEC-A nrPDB Length = 264 Score = 32.3 bits (72), Expect = 0.27, Method: Compositional matrix adjust. Identities = 15/35 (42%), Positives = 21/35 (60%) Query: 61 VLDVACGTGVDSIMLVEEGFSVTSVDASDKMLKYA 95 VLD CGTG D++ L G++VT +D S + A Sbjct: 63 VLDAGCGTGEDALHLAGLGYAVTGLDLSPTAISVA 97 >3CCF-A nrPDB Length = 279 Score = 32.0 bits (71), Expect = 0.32, Method: Compositional matrix adjust. Identities = 24/81 (29%), Positives = 35/81 (43%), Gaps = 4/81 (4%) Query: 25 GEAARVWQLYI-GDTRSRTAEYKAWLLGLLRQHGCQRVLDVACGTGVDSIMLVEEGFSVT 83 G A W + D S +Y LL LL + +LD+ CGTG + + + G V Sbjct: 24 GTAKNFWDATLYQDKHSFVWQYGEDLLQLLNPQPGEFILDLGCGTGQLTEKIAQSGAEVL 83 Query: 84 SVDASDKMLKYALKERWNRRH 104 D + M++ K R N H Sbjct: 84 GTDNAATMIE---KARQNYPH 101 >4FS8-A nrPDB Length = 383 Score = 31.6 bits (70), Expect = 0.38, Method: Compositional matrix adjust. Identities = 46/139 (33%), Positives = 60/139 (43%), Gaps = 28/139 (20%) Query: 61 VLDVACGTGVDSIM---LVEEGFSVTSVDASDKMLKYALK------ERW---NRRHEPAF 108 VLD+ CGTG D + LV E V VD D L+ A K E++ R F Sbjct: 87 VLDLGCGTGRDVYLASKLVGEHGKVIGVDMLDNQLEVARKYVEYHAEKFFGSPSRSNVRF 146 Query: 109 DKWVIEEANWMTLDKD-VPQSAEGGFDAVICLGNSFAHLPDCKGDQSEHRLAL-KNIASM 166 K IE N T + + VP S+ D VI +C + S ++LAL K I + Sbjct: 147 LKGFIE--NLATAEPEGVPDSS---VDIVI---------SNCVCNLSTNKLALFKEIHRV 192 Query: 167 VRAGGLLVIDHRNYDHILS 185 +R GG L D LS Sbjct: 193 LRDGGELYFSDVYADRRLS 211 >4QDJ-A nrPDB Length = 238 Score = 31.6 bits (70), Expect = 0.42, Method: Compositional matrix adjust. Identities = 28/90 (31%), Positives = 39/90 (43%), Gaps = 17/90 (18%) Query: 61 VLDVACGTGVDSIMLVEEGFSVTSVDASDKMLKYA---LKERWNRRHEPAFDKWVIEEAN 117 V D CG G SI L + G V D S+KM+ A +E ++P F Sbjct: 66 VCDAGCGVGSLSIPLAQAGALVYGSDISEKMVGEAQQKAQEVLAYGNQPTF--------- 116 Query: 118 WMTLDKDVPQSAEGGFDAVICLGNSFAHLP 147 + +D+ Q G +D VICL + H P Sbjct: 117 ---MTQDLAQLG-GKYDTVICL-DVLIHYP 141 >4P7C-A nrPDB Length = 322 Score = 31.2 bits (69), Expect = 0.55, Method: Compositional matrix adjust. Identities = 32/116 (27%), Positives = 53/116 (45%), Gaps = 15/116 (12%) Query: 59 QRVLDVACGTGVDSIMLVEEGFSVTSVDASDKMLKYALKERWNRRHEPAFDKWVIEEANW 118 +RVLDV CG G ++ G SV D + + + +R+ P W + A Sbjct: 123 KRVLDVGCGNGYYQWRML--GAGADSVIGVDPNWLFFCQFQAMQRYLPDLPAWHLPFAL- 179 Query: 119 MTLDKDVPQSAEGGFDAVICLGNSFAHLPDCKGDQSEHRLALKNIASMVRAGGLLV 174 +D+P + E GFD V +G + + +H LALK+ +V+ G L++ Sbjct: 180 ----EDLPANLE-GFDTVFSMGVLYH-----RKSPIDHLLALKD--CLVKGGELVM 223 >4HTF-A nrPDB Length = 285 Score = 30.0 bits (66), Expect = 1.1, Method: Compositional matrix adjust. Identities = 26/92 (28%), Positives = 41/92 (44%), Gaps = 4/92 (4%) Query: 8 TRSLGVAAEGLPDQYADGEAARVWQLYIGDTRSRTAEYKAW--LLGLLRQHGCQ--RVLD 63 T +L + + D+ D A + + G T+ + + W L +L + G Q RVLD Sbjct: 15 TENLYFQSNAMQDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLD 74 Query: 64 VACGTGVDSIMLVEEGFSVTSVDASDKMLKYA 95 G G +I + E G V D S +M+ A Sbjct: 75 AGGGEGQTAIKMAERGHQVILCDLSAQMIDRA 106 >3M70-A nrPDB Length = 286 Score = 29.6 bits (65), Expect = 1.5, Method: Compositional matrix adjust. Identities = 16/44 (36%), Positives = 26/44 (59%), Gaps = 2/44 (4%) Query: 60 RVLDVACGTGVDSIMLVEEGFSVTSVDASDKMLKY--ALKERWN 101 +VLD+ CG G +S+ L G+ VTS D ++ + + KE+ N Sbjct: 123 KVLDLGCGQGRNSLYLSLLGYDVTSWDHNENSIAFLNETKEKEN 166 >2I6G-A nrPDB Length = 199 Score = 29.6 bits (65), Expect = 1.5, Method: Compositional matrix adjust. Identities = 12/29 (41%), Positives = 18/29 (62%) Query: 60 RVLDVACGTGVDSIMLVEEGFSVTSVDAS 88 R LD+ CG G +S+ L G+ VT+ D + Sbjct: 34 RTLDLGCGNGRNSLYLAANGYDVTAWDKN 62 >3L8D-A nrPDB Length = 242 Score = 29.6 bits (65), Expect = 1.5, Method: Compositional matrix adjust. Identities = 16/40 (40%), Positives = 21/40 (52%), Gaps = 1/40 (2%) Query: 60 RVLDVACGTGVDSIMLVEEGFSVTSVDASDKMLKYALKER 99 VLDV CG G + L G+ VD S+ M++ KER Sbjct: 56 EVLDVGCGDGYGTYKLSRTGYKAVGVDISEVMIQKG-KER 94 >1VRM-A nrPDB Length = 325 Score = 29.3 bits (64), Expect = 2.1, Method: Compositional matrix adjust. Identities = 24/98 (24%), Positives = 42/98 (42%), Gaps = 9/98 (9%) Query: 119 MTLDKDVPQSAEGGFDAVICLGNSFAHLP------DCKGDQSEHRLALKN--IASMVRAG 170 ++ D++ E G D I +G F P D +GD + LK+ +A+ Sbjct: 179 LSFDENATGFVEAGGDVRI-IGPKFGKYPWVIGVKDPRGDDVIDYIYLKSGAVATSGDYE 237 Query: 171 GLLVIDHRNYDHILSTGCAPPGKNIYYKSDLTKDVTTS 208 V+D Y HIL P + ++ + + +D TT+ Sbjct: 238 RYFVVDGVRYHHILDPSTGYPARGVWSVTIIAEDATTA 275 >5EGS-A nrPDB Length = 376 Score = 29.3 bits (64), Expect = 2.2, Method: Compositional matrix adjust. Identities = 23/54 (42%), Positives = 29/54 (53%), Gaps = 7/54 (12%) Query: 39 RSRTAEYKAWLLGLLRQHGCQR---VLDVACGTGVDSIMLVEEGF-SVTSVDAS 88 R RT Y+ LG+LR R VLDV GTG+ SI + G V +V+AS Sbjct: 65 RVRTDAYR---LGILRNWAALRGKTVLDVGAGTGILSIFCAQAGARRVYAVEAS 115 >5F8E-A nrPDB Length = 377 Score = 29.3 bits (64), Expect = 2.3, Method: Compositional matrix adjust. Identities = 34/154 (22%), Positives = 57/154 (37%), Gaps = 22/154 (14%) Query: 61 VLDVACGTGVDSIMLVEEGFSV---TSVDASDKMLKYALKERWNRRHEPAFDKWVIEEAN 117 V D CG+G ++ L+ + F T +D SD+ + +E E + Sbjct: 191 VADFGCGSG-RAVKLMAQAFGASRFTGIDFSDEAVAAGTEEAARL----GLANATFERHD 245 Query: 118 WMTLDKDVPQSAEGGFDAVICLGNSFAHLPDCKGDQSEHRLALKNIASMVRAGGLLVIDH 177 LDK G +D + D DQ++ L+NI +R GG+L++ Sbjct: 246 LAELDK------VGAYDVITVF--------DAIHDQAQPARVLQNIYRALRPGGVLLMVD 291 Query: 178 RNYDHILSTGCAPPGKNIYYKSDLTKDVTTSVLI 211 L P Y + L +T S+ + Sbjct: 292 IKASSQLEDNVGVPLSTYLYTTSLMHCMTVSLAL 325 >5WP4-A nrPDB Length = 491 Score = 28.9 bits (63), Expect = 2.5, Method: Compositional matrix adjust. Identities = 15/40 (37%), Positives = 22/40 (55%), Gaps = 1/40 (2%) Query: 59 QRVLDVACGTGVDSIMLVEE-GFSVTSVDASDKMLKYALK 97 Q+VLDV CG G + E+ V +D S M+ +AL+ Sbjct: 284 QKVLDVGCGIGGGDFYMAEKFDVHVVGIDLSVNMISFALE 323 >2ODR-C nrPDB Length = 701 Score = 28.9 bits (63), Expect = 2.9, Method: Compositional matrix adjust. Identities = 33/128 (25%), Positives = 57/128 (44%), Gaps = 13/128 (10%) Query: 62 LDVACGTGVDSIMLVEEGFSVTSVDASDKMLKYALKERWNR--RHEPAFDKWVIEEANW- 118 +D+ G + +L + GF+ +K KY E + P +W +E A + Sbjct: 260 VDINDGKAIAEGLLSQFGFTNFKFIPDEKKSKYYTPETQTEVYAYHPKLKEW-LEVATFG 318 Query: 119 ----MTLDK---DVPQSAEG-GFDAVICLGNSFAHLPDCKGDQ-SEHRLALKNIASMVRA 169 + L K DVP G G + + + +FA + + Q EH+L +N+ASMV+ Sbjct: 319 VYSPVALSKYGIDVPVMNLGLGVERLAMISGNFADVREMVYPQFYEHKLNDRNVASMVKL 378 Query: 170 GGLLVIDH 177 + V+D Sbjct: 379 DKVPVMDE 386 >5WP5-A nrPDB Length = 491 Score = 28.5 bits (62), Expect = 3.4, Method: Compositional matrix adjust. Identities = 15/40 (37%), Positives = 21/40 (52%), Gaps = 1/40 (2%) Query: 59 QRVLDVACGTGVDSIMLVEE-GFSVTSVDASDKMLKYALK 97 Q+VLDV CG G + E V +D S M+ +AL+ Sbjct: 284 QKVLDVGCGIGGGDFYMAENFDVHVVGIDLSVNMISFALE 323 >5GM1-A nrPDB Length = 297 Score = 28.5 bits (62), Expect = 3.8, Method: Compositional matrix adjust. Identities = 16/52 (30%), Positives = 26/52 (50%), Gaps = 1/52 (1%) Query: 45 YKAWLLGLLRQHGCQRVLDVACGTGVDSIMLV-EEGFSVTSVDASDKMLKYA 95 Y +L+ L Q +LD+ CGTG ++ + G +VT V S + + A Sbjct: 65 YTDYLIETLDPKAGQHLLDIGCGTGRTALKAARQRGIAVTGVAVSKEQIAAA 116 >6H65-A nrPDB Length = 317 Score = 28.5 bits (62), Expect = 4.0, Method: Compositional matrix adjust. Identities = 19/49 (38%), Positives = 23/49 (46%), Gaps = 10/49 (20%) Query: 12 GVAAEGLP------DQYADGEAA----RVWQLYIGDTRSRTAEYKAWLL 50 G AE LP Q DGE R+ +LY G T + YK+WLL Sbjct: 265 GTIAEILPVTTIDRIQVGDGEVGPVTRRLQELYFGVTSGQLEAYKSWLL 313 >1DUS-A nrPDB Length = 194 Score = 27.7 bits (60), Expect = 5.6, Method: Compositional matrix adjust. Identities = 14/35 (40%), Positives = 20/35 (57%) Query: 61 VLDVACGTGVDSIMLVEEGFSVTSVDASDKMLKYA 95 +LD+ CG GV I L +E S T D + + +K A Sbjct: 56 ILDLGCGYGVIGIALADEVKSTTMADINRRAIKLA 90 >5JMQ-A nrPDB Length = 446 Score = 27.7 bits (60), Expect = 6.0, Method: Compositional matrix adjust. Identities = 20/72 (27%), Positives = 34/72 (47%), Gaps = 2/72 (2%) Query: 20 DQYADGEAARVWQLYIGDTRSRTAEYKAWLLGLLRQHGCQRVLDVACGTGVDSIMLVEEG 79 ++Y D L + + RT +Y + +L + +LDV CGTG+ S+ Sbjct: 113 EEYFDSYGTLKLHLEMLADQPRTTKYHSVILQNKESLKDKVILDVGCGTGIISLFCAHHA 172 Query: 80 F--SVTSVDASD 89 +V +V+ASD Sbjct: 173 RPKAVYAVEASD 184 >1Y8C-A nrPDB Length = 246 Score = 27.7 bits (60), Expect = 6.0, Method: Compositional matrix adjust. Identities = 25/119 (21%), Positives = 57/119 (47%), Gaps = 15/119 (12%) Query: 62 LDVACGTGVDSIMLVEEGFSVTSVDASDKMLKYALKERWNRRHEPAFDKWVIEEANWMTL 121 LD+ACGTG + L + + +VD S +ML A + ++ +P + ++ + + + Sbjct: 42 LDLACGTGNLTENLCPKFKNTWAVDLSQEMLSEAENKFRSQGLKP---RLACQDISNLNI 98 Query: 122 DKDVPQSAEGGFDAVICLGNSFAHLPDCKGDQSEHRLALKNIASMVRAGGLLVIDHRNY 180 ++ FD + C +S ++ D + + K +++ ++ GG+ + D +Y Sbjct: 99 NR--------KFDLITCCLDSTNYII----DSDDLKKYFKAVSNHLKEGGVFIFDINSY 145 >1RI1-A nrPDB Length = 298 Score = 27.7 bits (60), Expect = 6.1, Method: Compositional matrix adjust. Identities = 44/160 (27%), Positives = 66/160 (41%), Gaps = 15/160 (9%) Query: 46 KAWLLGLLRQHGCQRVLDVACGTGVDSIMLVEEGF-SVTSVDASDKMLKYA-LKERWNRR 103 KA L+ L + G VLD+ CG G D + G VD ++ + A ++ R +R Sbjct: 54 KACLIRLYTKRG-DSVLDLGCGKGGDLLKYERAGIGEYYGVDIAEVSINDARVRARNMKR 112 Query: 104 HEPAFDKWVIEEANWMTLDKDVPQSAEGGFDAVICLGNSFAHLPDCKGDQSEHRLALKNI 163 F + M L K+ FD VI SF H + + +A +NI Sbjct: 113 RFKVFFRAQDSYGRHMDLGKE--------FD-VISSQFSF-HYAFSTSESLD--IAQRNI 160 Query: 164 ASMVRAGGLLVIDHRNYDHILSTGCAPPGKNIYYKSDLTK 203 A +R GG ++ + D IL N +YK +L K Sbjct: 161 ARHLRPGGYFIMTVPSRDVILERYKQGRMSNDFYKIELEK 200 >6G8G-A nrPDB Length = 214 Score = 27.7 bits (60), Expect = 6.8, Method: Compositional matrix adjust. Identities = 19/74 (25%), Positives = 33/74 (44%), Gaps = 2/74 (2%) Query: 74 MLVEEGFSVTSVDASDKM--LKYALKERWNRRHEPAFDKWVIEEANWMTLDKDVPQSAEG 131 + +E+GFS TS+DA K + A + E F ++ E + D VP+ + G Sbjct: 33 LFLEQGFSATSMDAIAKAAGVSKATLYAYFPSKEALFASLIVAECESLQRDLPVPKLSAG 92 Query: 132 GFDAVICLGNSFAH 145 +A+ + H Sbjct: 93 LSEALRDFARQYLH 106 >3BXO-A nrPDB Length = 239 Score = 27.3 bits (59), Expect = 7.8, Method: Compositional matrix adjust. Identities = 14/40 (35%), Positives = 20/40 (50%) Query: 58 CQRVLDVACGTGVDSIMLVEEGFSVTSVDASDKMLKYALK 97 +LDVACGTG +E ++ S+ ML +A K Sbjct: 41 ASSLLDVACGTGTHLEHFTKEFGDTAGLELSEDMLTHARK 80 >5LV5-A nrPDB Length = 403 Score = 27.3 bits (59), Expect = 8.2, Method: Compositional matrix adjust. Identities = 19/47 (40%), Positives = 27/47 (57%), Gaps = 4/47 (8%) Query: 46 KAWLLGLLRQHGCQR---VLDVACGTGVDSIMLVEEGF-SVTSVDAS 88 +A+ LG+L+ R VLDV GTG+ SI + G V +V+AS Sbjct: 96 EAYRLGILKNWAALRGKTVLDVGAGTGILSIFCAQAGARRVYAVEAS 142 >6D05-C nrPDB Length = 698 Score = 27.3 bits (59), Expect = 8.6, Method: Compositional matrix adjust. Identities = 24/70 (34%), Positives = 33/70 (47%), Gaps = 5/70 (7%) Query: 128 SAEGGFDAVICLGNSFAHLP--DCKGDQSEHRLALKNIASMVRAGGLLV--IDHRNYDHI 183 + E G+ AV + S + L + KG +S H A+ A GLL I+H +D Sbjct: 440 TPEAGYFAVAVVKKSASDLTWDNLKGKKSCH-TAVGRTAGWNIPMGLLYNKINHCRFDEF 498 Query: 184 LSTGCAPPGK 193 S GCAP K Sbjct: 499 FSEGCAPGSK 508 >2VS1-A nrPDB Length = 425 Score = 27.3 bits (59), Expect = 9.1, Method: Compositional matrix adjust. Identities = 11/39 (28%), Positives = 23/39 (58%) Query: 59 QRVLDVACGTGVDSIMLVEEGFSVTSVDASDKMLKYALK 97 +++LD+ G G I L + GF+V D+++ ++ A + Sbjct: 292 EKILDMYSGVGTFGIYLAKRGFNVKGFDSNEFAIEMARR 330 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 1R74-A nrPDB 492 e-139 1D2C-A nrPDB 480 e-136 5H02-A nrPDB 288 2e-78 3D2L-A nrPDB 137 5e-33 2AVN-A nrPDB 123 1e-28 5BSZ-A nrPDB 109 1e-24 Sequences not found previously or not previously below threshold: 6M83-A nrPDB 65 4e-11 3BXO-A nrPDB 62 2e-10 1Y8C-A nrPDB 58 6e-09 2GLU-A nrPDB 56 2e-08 3CCF-A nrPDB 53 2e-07 5GM1-A nrPDB 51 4e-07 3BUS-A nrPDB 51 8e-07 5F8E-A nrPDB 50 1e-06 3SM3-A nrPDB 50 1e-06 4KDR-A nrPDB 49 2e-06 4KDC-A nrPDB 49 3e-06 3MGG-A nrPDB 48 4e-06 3L8D-A nrPDB 48 6e-06 4PNE-A nrPDB 48 6e-06 5JE5-A nrPDB 47 9e-06 2GS9-A nrPDB 46 2e-05 4QTT-B nrPDB 46 2e-05 5U19-A nrPDB 46 2e-05 4NEC-A nrPDB 45 5e-05 1RI1-A nrPDB 44 6e-05 6MRO-A nrPDB 43 1e-04 3E23-A nrPDB 42 3e-04 3EGE-A nrPDB 42 3e-04 3DP7-A nrPDB 42 3e-04 6G4W-q nrPDB 42 4e-04 4INE-A nrPDB 41 4e-04 3JWJ-A nrPDB 41 5e-04 4HTF-A nrPDB 41 6e-04 4KRI-A nrPDB 41 6e-04 5BP9-A nrPDB 41 8e-04 3LCC-A nrPDB 41 0.001 5WP5-A nrPDB 39 0.002 5WP4-A nrPDB 39 0.002 3OU6-A nrPDB 39 0.002 5Z9O-A nrPDB 39 0.003 4QDJ-A nrPDB 39 0.003 3BKW-A nrPDB 39 0.003 2I6G-A nrPDB 39 0.003 5EVJ-A nrPDB 39 0.003 2B3T-A nrPDB 38 0.005 2P35-A nrPDB 37 0.008 3HNR-A nrPDB 37 0.009 5MGZ-A nrPDB 37 0.010 6DCC-A nrPDB 37 0.011 2PJD-A nrPDB 37 0.014 5E72-A nrPDB 36 0.015 4HGY-A nrPDB 36 0.015 5M58-A nrPDB 36 0.016 5I2H-A nrPDB 36 0.017 1VBF-A nrPDB 36 0.019 4FS8-A nrPDB 36 0.024 2YR0-A nrPDB 36 0.025 1TPY-A nrPDB 35 0.035 3HEM-A nrPDB 35 0.042 2VS1-A nrPDB 35 0.042 4KIC-A nrPDB 35 0.043 4DZR-A nrPDB 35 0.044 1NKV-A nrPDB 35 0.048 1UWV-A nrPDB 35 0.049 4P7C-A nrPDB 34 0.057 3MCZ-A nrPDB 34 0.058 3M70-A nrPDB 34 0.068 3G5T-A nrPDB 34 0.071 4YMH-A nrPDB 34 0.076 1WXW-A nrPDB 34 0.081 3JWI-A nrPDB 34 0.082 6BQC-A nrPDB 34 0.083 4RYL-A nrPDB 34 0.083 1N2X-A nrPDB 34 0.086 5EGS-A nrPDB 34 0.091 1L3B-A nrPDB 34 0.10 5W7M-A nrPDB 34 0.11 5X7F-A nrPDB 34 0.11 1G6Q-1 nrPDB 33 0.12 6CU3-A nrPDB 33 0.12 1X1B-A nrPDB 33 0.13 3I9F-A nrPDB 33 0.14 5LV5-A nrPDB 33 0.14 3BKX-A nrPDB 33 0.14 1KP9-A nrPDB 33 0.19 1F3L-A nrPDB 33 0.20 5BP7-A nrPDB 32 0.21 2XVM-A nrPDB 32 0.27 4HG2-A nrPDB 32 0.28 5JMQ-A nrPDB 32 0.29 1Q2L-A nrPDB 32 0.30 3DMF-A nrPDB 32 0.31 3SVZ-A nrPDB 32 0.33 6GKZ-A nrPDB 32 0.40 4AZW-A nrPDB 31 0.48 4AZV-A nrPDB 31 0.48 1P91-A nrPDB 31 0.52 2HNK-A nrPDB 31 0.82 4QNV-A nrPDB 31 0.83 4DCM-A nrPDB 31 0.84 5KPG-A nrPDB 31 0.86 3CJR-A nrPDB 31 0.88 3V8V-A nrPDB 30 1.0 1VQ1-A nrPDB 30 1.1 1PJZ-A nrPDB 30 1.5 2YXL-A nrPDB 30 1.6 5E9J-A nrPDB 30 1.6 3BGV-A nrPDB 30 1.6 5FUB-A nrPDB 30 1.7 1NW6-A nrPDB 29 1.8 5XN8-A nrPDB 29 2.0 1DUS-A nrPDB 29 2.0 1DL5-A nrPDB 29 2.1 3M6U-A nrPDB 29 2.2 2H1R-A nrPDB 29 2.4 3NJR-A nrPDB 29 2.5 2H11-A nrPDB 29 2.6 2YVL-A nrPDB 29 2.7 3X0D-A nrPDB 29 2.9 1FP2-A nrPDB 29 3.0 6OGN-A nrPDB 29 3.3 1WF3-A nrPDB 28 4.3 2PWY-A nrPDB 28 4.3 6IWT-A nrPDB 28 4.6 2QYO-A nrPDB 28 4.7 3BGI-A nrPDB 28 5.0 5XOH-A nrPDB 28 5.1 1KYW-A nrPDB 28 5.4 4EVI-A nrPDB 28 5.9 2BGN-E nrPDB 27 6.5 3TTS-A nrPDB 27 7.5 >1R74-A nrPDB Length = 294 Score = 492 bits (1265), Expect = e-139, Method: Composition-based stats. Identities = 294/294 (100%), Positives = 294/294 (100%) Query: 2 VDSVYRTRSLGVAAEGLPDQYADGEAARVWQLYIGDTRSRTAEYKAWLLGLLRQHGCQRV 61 VDSVYRTRSLGVAAEGLPDQYADGEAARVWQLYIGDTRSRTAEYKAWLLGLLRQHGCQRV Sbjct: 1 VDSVYRTRSLGVAAEGLPDQYADGEAARVWQLYIGDTRSRTAEYKAWLLGLLRQHGCQRV 60 Query: 62 LDVACGTGVDSIMLVEEGFSVTSVDASDKMLKYALKERWNRRHEPAFDKWVIEEANWMTL 121 LDVACGTGVDSIMLVEEGFSVTSVDASDKMLKYALKERWNRRHEPAFDKWVIEEANWMTL Sbjct: 61 LDVACGTGVDSIMLVEEGFSVTSVDASDKMLKYALKERWNRRHEPAFDKWVIEEANWMTL 120 Query: 122 DKDVPQSAEGGFDAVICLGNSFAHLPDCKGDQSEHRLALKNIASMVRAGGLLVIDHRNYD 181 DKDVPQSAEGGFDAVICLGNSFAHLPDCKGDQSEHRLALKNIASMVRAGGLLVIDHRNYD Sbjct: 121 DKDVPQSAEGGFDAVICLGNSFAHLPDCKGDQSEHRLALKNIASMVRAGGLLVIDHRNYD 180 Query: 182 HILSTGCAPPGKNIYYKSDLTKDVTTSVLIVNNKAHMVTLDYTVQVPGAGQDGSPGLSKF 241 HILSTGCAPPGKNIYYKSDLTKDVTTSVLIVNNKAHMVTLDYTVQVPGAGQDGSPGLSKF Sbjct: 181 HILSTGCAPPGKNIYYKSDLTKDVTTSVLIVNNKAHMVTLDYTVQVPGAGQDGSPGLSKF 240 Query: 242 RLSYYPHCLASFTELLQAAFGGKCQHSVLGDFKPYKPGQTYIPCYFIHVLKRTD 295 RLSYYPHCLASFTELLQAAFGGKCQHSVLGDFKPYKPGQTYIPCYFIHVLKRTD Sbjct: 241 RLSYYPHCLASFTELLQAAFGGKCQHSVLGDFKPYKPGQTYIPCYFIHVLKRTD 294 >1D2C-A nrPDB Length = 292 Score = 480 bits (1235), Expect = e-136, Method: Composition-based stats. Identities = 270/293 (92%), Positives = 281/293 (95%), Gaps = 2/293 (0%) Query: 2 VDSVYRTRSLGVAAEGLPDQYADGEAARVWQLYIGDTRSRTAEYKAWLLGLLRQHGCQRV 61 VDSVYRTRSLGVAAEG+PDQYADGEAARVWQLYIGDTRSRTAEYKAWLLGLLRQHGC RV Sbjct: 1 VDSVYRTRSLGVAAEGIPDQYADGEAARVWQLYIGDTRSRTAEYKAWLLGLLRQHGCHRV 60 Query: 62 LDVACGTGVDSIMLVEEGFSVTSVDASDKMLKYALKERWNRRHEPAFDKWVIEEANWMTL 121 LDVACGTGVDSIMLVEEGFSVTSVDASDKMLKYALKERWNRR EPAFDKWVIEEANW+TL Sbjct: 61 LDVACGTGVDSIMLVEEGFSVTSVDASDKMLKYALKERWNRRKEPAFDKWVIEEANWLTL 120 Query: 122 DKDVPQSAEGGFDAVICLGNSFAHLPDCKGDQSEHRLALKNIASMVRAGGLLVIDHRNYD 181 DKDVP A GFDAVICLGNSFAHLPD KGDQSEHRLALKNIASMVR GGLLVIDHRNYD Sbjct: 121 DKDVP--AGDGFDAVICLGNSFAHLPDSKGDQSEHRLALKNIASMVRPGGLLVIDHRNYD 178 Query: 182 HILSTGCAPPGKNIYYKSDLTKDVTTSVLIVNNKAHMVTLDYTVQVPGAGQDGSPGLSKF 241 +ILSTGCAPPGKNIYYKSDLTKD+TTSVL VNNKAHMVTLDYTVQVPGAG+DG+PG SKF Sbjct: 179 YILSTGCAPPGKNIYYKSDLTKDITTSVLTVNNKAHMVTLDYTVQVPGAGRDGAPGFSKF 238 Query: 242 RLSYYPHCLASFTELLQAAFGGKCQHSVLGDFKPYKPGQTYIPCYFIHVLKRT 294 RLSYYPHCLASFTEL+Q AFGG+CQHSVLGDFKPY+PGQ Y+PCYFIHVLK+T Sbjct: 239 RLSYYPHCLASFTELVQEAFGGRCQHSVLGDFKPYRPGQAYVPCYFIHVLKKT 291 >5H02-A nrPDB Length = 283 Score = 288 bits (736), Expect = 2e-78, Method: Composition-based stats. Identities = 87/281 (30%), Positives = 136/281 (48%), Gaps = 37/281 (13%) Query: 15 AEGLPDQYADGEAARVWQLYIGDTRSRTAEYKAWLLGLLRQHGCQRVLDVACGTGVDSIM 74 ++G ++Y G + W I D SR ++ +L++ G ++VLDVA GTG +S+ Sbjct: 39 SDGYTNEYVSGFVDK-WDELI-DWESRAESEGDTIINILKERGVKKVLDVATGTGFNSVR 96 Query: 75 LVEEGFSVTSVDASDKMLKYALKERWNRRHEPAFDKWVIEEANWMTLDKDVPQSAEGGFD 134 L++ GF V S D S +ML A N R + V +A+W ++KD+ FD Sbjct: 97 LLQAGFDVVSADGSAEMLVKAFD---NARDHGYLMRTV--QADWRWMNKDIHDK----FD 147 Query: 135 AVICLGNSFAHLPDCKGDQSEHRLALKNIASMVRAGGLLVIDHRNYDHILSTGCAPPGKN 194 A++CLGNSF HL D+ + R AL ++++ G+L++D RNYD IL G + + Sbjct: 148 AIVCLGNSFTHLF----DEGDRRKALAEFYALLKHDGVLLLDQRNYDAILDDGYSSKHAH 203 Query: 195 IYYKSDLTKDVTTSVLIVNNKAHMVTLDYTVQVPGAGQDGSPGLSKFRLSYYPHCLASFT 254 YY D T SV + + Y DGS + L+ +P Sbjct: 204 -YYCGD-----TVSVYPEHVDEGLARFKYEF------SDGSV----YNLNMFPLRKDYTR 247 Query: 255 ELLQAAFGGKCQHSVLGDFKP-YKPGQTYIPCYFIHVLKRT 294 +LL G + + LGDFK YK + P +F+HV ++ Sbjct: 248 QLLHEV--GFQEINTLGDFKETYKEDE---PDFFLHVAEKN 283 >3D2L-A nrPDB Length = 243 Score = 137 bits (345), Expect = 5e-33, Method: Composition-based stats. Identities = 56/263 (21%), Positives = 110/263 (41%), Gaps = 40/263 (15%) Query: 34 YIGDTRSRTAEYKAWLLGLLRQ-HGCQRVLDVACGTGVDSIMLVEEGFSVTSVDASDKML 92 Y+ D + Y W+ +L Q +R+ D+ CGTG +++L + + VT VD S++ML Sbjct: 9 YVYDELMQDVPYPEWVAWVLEQVEPGKRIADIGCGTGTATLLLADH-YEVTGVDLSEEML 67 Query: 93 KYAL-KERWNRRHEPAFDKWVIEEANWMTLDKDVPQSAEGGFDAVICLGNSFAHLPDCKG 151 + A K RH D WV + + ++P+ DA+ L +S +L Sbjct: 68 EIAQEKAMETNRH---VDFWVQD-----MRELELPEPV----DAITILCDSLNYL----Q 111 Query: 152 DQSEHRLALKNIASMVRAGGLLVID-HRNY--DHILSTGCAPPGKNIYYKSDLTKDVTTS 208 +++ + + A ++ GG L+ D H Y + + + + ++ Sbjct: 112 TEADVKQTFDSAARLLTDGGKLLFDVHSPYKMETLFNGKTYATHA----------EQSSY 161 Query: 209 VLIVNNKAHMVTLDYTVQVPGAGQDG---SPGLSKFRLSYYPHCLASFTELLQAAFGGKC 265 + + +++ + + G+DG + + +Y P + L+ A G Sbjct: 162 IWFADPGEEPLSVVHELTFFIEGEDGRYDRVDETHHQRTYPP---EQYITWLREA--GFR 216 Query: 266 QHSVLGDFKPYKPGQTYIPCYFI 288 +V GDFK P +T +F+ Sbjct: 217 VCAVTGDFKSDAPTETAERIFFV 239 >2AVN-A nrPDB Length = 260 Score = 123 bits (307), Expect = 1e-28, Method: Composition-based stats. Identities = 45/162 (27%), Positives = 70/162 (43%), Gaps = 32/162 (19%) Query: 29 RVWQLYIGDTRSRTAEYKA--W-----LLGLLRQHGCQ---RVLDVACGTGVDSIMLVEE 78 R W+ Y R+ + Y+ W L+G + + RVLD+ GTG S+ L E Sbjct: 16 RSWEFYDRIARAYDSMYETPKWKLYHRLIGSFLEEYLKNPCRVLDLGGGTGKWSLFLQER 75 Query: 79 GFSVTSVDASDKMLKYALKERWNRRHEPAFDKWVIEEANWMTLDKDVPQSAEGGFDAVIC 138 GF V VD S +ML+ A E V +A +D+P + G F+AV+ Sbjct: 76 GFEVVLVDPSKEMLEVA--------REKGVKNVVEAKA------EDLPFPS-GAFEAVLA 120 Query: 139 LGNSFAHLPDCKGDQSEHRLALKNIASMVRAGGLLVIDHRNY 180 LG+ +++ + SE R + GLL+ N+ Sbjct: 121 LGDVLSYVENKDKAFSEIRRV-------LVPDGLLIATVDNF 155 >5BSZ-A nrPDB Length = 250 Score = 109 bits (273), Expect = 1e-24, Method: Composition-based stats. Identities = 48/167 (28%), Positives = 69/167 (41%), Gaps = 22/167 (13%) Query: 12 GVAAEGLPDQYADGEAARVWQLYIGDTRSRTAEYKAWLLGLLRQH--GCQRVLDVACGTG 69 G A G Y D V+ L+ A W+ ++R+ G + +LDVACGTG Sbjct: 1 GHMAVGSTSVYGDA-LGEVYDLFYRGRGKDFAAEAEWVRRVVRERRPGARSLLDVACGTG 59 Query: 70 VDSIMLVEEGFSVTSVDASDKMLKYALKERWNRRHEPAFDKWVIEEANWMTLDKDVPQSA 129 LVE V+ S M A E + +A+ D D+ + Sbjct: 60 EHLAHLVEHFPDAAGVELSPAMRAAA---------ERKLTATPVHQAD--MFDFDLGRV- 107 Query: 130 EGGFDAVICLGNSFAHLPDCKGDQSEHRLALKNIASMVRAGGLLVID 176 FDAV CL S A+ D +E A++ +A + GG+LVID Sbjct: 108 ---FDAVCCLTGSIAY----AADTAELARAVRAMARHLPVGGVLVID 147 >6M83-A nrPDB Length = 263 Score = 64.8 bits (156), Expect = 4e-11, Method: Composition-based stats. Identities = 45/176 (25%), Positives = 72/176 (40%), Gaps = 21/176 (11%) Query: 19 PDQYADGEAARVWQLYIGDTRSRTAEYKAWLLGLLRQHGCQ--RVLDVACGTGVDSIMLV 76 P GE A ++ L A L L+R+H + +LDVACGTG+ L Sbjct: 10 PQADYSGEIAELYDLVHQGKGKDYHREAADLAALVRRHSPKAASLLDVACGTGMHLRHLA 69 Query: 77 EEGFSVTSVDASDKMLKYALKERWNRRHEPAFDKWVIEEANWMTLDKDVPQSAEGGFDAV 136 + +V ++ S ML A RR P V+ + D + + F AV Sbjct: 70 DSFGTVEGLELSADMLAIA------RRRNP---DAVLHHGD--MRDFSLGRR----FSAV 114 Query: 137 ICLGNSFAHLPDCKGDQSEHRLALKNIASMVRAGGLLVIDHRNYDHILSTGCAPPG 192 C+ ++ HL Q+E AL+ A+ V G++V++ + + G G Sbjct: 115 TCMFSAIGHL----AGQAELDAALERFAAHVLPDGVVVVEPWWFPENFTPGYVAAG 166 >3BXO-A nrPDB Length = 239 Score = 62.1 bits (149), Expect = 2e-10, Method: Composition-based stats. Identities = 41/201 (20%), Positives = 72/201 (35%), Gaps = 25/201 (12%) Query: 33 LYIGDTRSRTAEYKAWLLGLLRQHG--CQRVLDVACGTGVDSIMLVEEGFSVTSVDASDK 90 Y+G + AE + L+R +LDVACGTG +E ++ S+ Sbjct: 15 FYLGRGKDYAAEASD-IADLVRSRTPEASSLLDVACGTGTHLEHFTKEFGDTAGLELSED 73 Query: 91 MLKYALKERWNRRHEPAFDKWVIEEANWMTLDKDVPQSAEGGFDAVICLGNSFAHLPDCK 150 ML +A K + D + + F AV+ + +S +L Sbjct: 74 MLTHARKRLPDATLHQG-----------DMRDFRLGRK----FSAVVSMFSSVGYL---- 114 Query: 151 GDQSEHRLALKNIASMVRAGGLLVIDHRNYDHILSTGCAPPGKNIYYKSDLTKDVTTSVL 210 E A+ + A + GG++V++ + + G + D S Sbjct: 115 KTTEELGAAVASFAEHLEPGGVVVVEPWWFPETFADGWVSADV---VRRDGRTVARVSHS 171 Query: 211 IVNNKAHMVTLDYTVQVPGAG 231 + A + + +TV PG G Sbjct: 172 VREGNATRMEVHFTVADPGKG 192 >1Y8C-A nrPDB Length = 246 Score = 57.9 bits (138), Expect = 6e-09, Method: Composition-based stats. Identities = 32/153 (20%), Positives = 66/153 (43%), Gaps = 21/153 (13%) Query: 34 YIGDTRSR-TAEYKAWLLGLLRQHGCQRV-----LDVACGTGVDSIMLVEEGFSVTSVDA 87 +I D R +YK W ++ + + LD+ACGTG + L + + +VD Sbjct: 8 HIYDKLIRADVDYKKWSDFIIEKCVENNLVFDDYLDLACGTGNLTENLCPKFKNTWAVDL 67 Query: 88 SDKMLKYALKERWNRRHEPAFDKWVIEEANWMTLDKDVPQSAEGGFDAVICLGNSFAHLP 147 S +ML A + ++ +P A + ++ + FD + C +S ++ Sbjct: 68 SQEMLSEAENKFRSQGLKPRL-------ACQDISNLNINRK----FDLITCCLDSTNYII 116 Query: 148 DCKGDQSEHRLALKNIASMVRAGGLLVIDHRNY 180 D + + K +++ ++ GG+ + D +Y Sbjct: 117 DSD----DLKKYFKAVSNHLKEGGVFIFDINSY 145 >2GLU-A nrPDB Length = 239 Score = 56.0 bits (133), Expect = 2e-08, Method: Composition-based stats. Identities = 24/120 (20%), Positives = 48/120 (40%), Gaps = 18/120 (15%) Query: 59 QRVLDVACGTGVDSIMLVEEGFSVTSVDASDKMLKYALKERWNRRHEPAFDKWVIEEANW 118 RVLD+ G G ++ VDA+ +M++ A + E + ++ Sbjct: 23 HRVLDIGAGAGHTALAFSPYVQECIGVDATKEMVEVA----SSFAQEKGVENVRFQQGTA 78 Query: 119 MTLDKDVPQSAEGGFDAVICLGNSFAHLPDCKGDQSEHRLALKNIASMVRAGGL-LVIDH 177 + +P + FD + C S+ R A++ +A +++ G L++DH Sbjct: 79 ----ESLPFP-DDSFDIITC--------RYAAHHFSDVRKAVREVARVLKQDGRFLLVDH 125 >3CCF-A nrPDB Length = 279 Score = 52.9 bits (125), Expect = 2e-07, Method: Composition-based stats. Identities = 43/180 (23%), Positives = 68/180 (37%), Gaps = 24/180 (13%) Query: 25 GEAARVWQLYIG-DTRSRTAEYKAWLLGLLRQHGCQRVLDVACGTGVDSIMLVEEGFSVT 83 G A W + D S +Y LL LL + +LD+ CGTG + + + G V Sbjct: 24 GTAKNFWDATLYQDKHSFVWQYGEDLLQLLNPQPGEFILDLGCGTGQLTEKIAQSGAEVL 83 Query: 84 SVDASDKMLKYALKERWNRRHEPAFDKWVIEEANWMTLDKDVPQSAEGGFDAVICLGNSF 143 D + M++ A R++ P V A+ D P DAV N+ Sbjct: 84 GTDNAATMIEKA------RQNYPHLHFDV---ADARNFRVDKP------LDAV--FSNAM 126 Query: 144 AH-LPDCKGDQSEHRLALKNIASMVRA----GGLLVIDHRNYDHILSTGCAPPGK-NIYY 197 H + + + + ALK+ V G + I Y+ + + G P N +Y Sbjct: 127 LHWVKEPEAAIASIHQALKSGGRFVAEFGGKGNIKYILEALYNALETLGIHNPQALNPWY 186 >5GM1-A nrPDB Length = 297 Score = 51.4 bits (121), Expect = 4e-07, Method: Composition-based stats. Identities = 29/153 (18%), Positives = 56/153 (36%), Gaps = 19/153 (12%) Query: 24 DGEAARVWQLYIGDTRSRTAEYKAWLLGLLRQHGCQRVLDVACGTGVDSIMLV-EEGFSV 82 D + +L ++++ Y +L+ L Q +LD+ CGTG ++ + G +V Sbjct: 45 DAPVPQDMELVTMSSQAQD-RYTDYLIETLDPKAGQHLLDIGCGTGRTALKAARQRGIAV 103 Query: 83 TSVDASDKMLKYALKERWNRRHEPAFDKWVIEEANWMTLDKDVPQSAEGGFDAVICLGNS 142 T V S + + A + V + D+ FD + S Sbjct: 104 TGVAVSKEQIAAANRLAAGHGLTERLTFEVADAMRLPYEDE--------SFDCAWAI-ES 154 Query: 143 FAHLPDCKGDQSEHRLALKNIASMVRAGGLLVI 175 H+ + AL +++ GG L++ Sbjct: 155 LCHM--------DRAKALGEAWRVLKPGGDLLV 179 >3BUS-A nrPDB Length = 273 Score = 50.6 bits (119), Expect = 8e-07, Method: Composition-based stats. Identities = 35/148 (23%), Positives = 53/148 (35%), Gaps = 19/148 (12%) Query: 31 WQLYIGDTRSRTAEYK--AWLLGLLRQHGCQRVLDVACGTGVDSIMLVE-EGFSVTSVDA 87 W+ D A + ++ LL RVLDV CG G ++ L VT + Sbjct: 33 WEDAGADVSVDDATDRLTDEMIALLDVRSGDRVLDVGCGIGKPAVRLATARDVRVTGISI 92 Query: 88 SDKMLKYALKERWNRRHEPAFDKWVIEEANWMTLDKDVPQSAEGGFDAVICLGNSFAHLP 147 S + A + D+P + FDAV L S H+P Sbjct: 93 SRPQVNQANARATAAGLANRVTFSYADA-------MDLPF-EDASFDAVWAL-ESLHHMP 143 Query: 148 DCKGDQSEHRLALKNIASMVRAGGLLVI 175 + AL+ +A ++R GG + I Sbjct: 144 -------DRGRALREMARVLRPGGTVAI 164 >5F8E-A nrPDB Length = 377 Score = 50.2 bits (118), Expect = 1e-06, Method: Composition-based stats. Identities = 33/158 (20%), Positives = 55/158 (34%), Gaps = 20/158 (12%) Query: 54 RQHGCQRVLDVACGTGVDSIMLVEEG--FSVTSVDASDKMLKYALKERWNRRHEPAFDKW 111 R V D CG+G ++ + T +D SD+ + +E Sbjct: 184 RLRSGADVADFGCGSGRAVKLMAQAFGASRFTGIDFSDEAVAAGTEEAARL----GLANA 239 Query: 112 VIEEANWMTLDKDVPQSAEGGFDAVICLGNSFAHLPDCKGDQSEHRLALKNIASMVRAGG 171 E + LDK G +D + + D DQ++ L+NI +R GG Sbjct: 240 TFERHDLAELDK------VGAYDVIT--------VFDAIHDQAQPARVLQNIYRALRPGG 285 Query: 172 LLVIDHRNYDHILSTGCAPPGKNIYYKSDLTKDVTTSV 209 +L++ L P Y + L +T S+ Sbjct: 286 VLLMVDIKASSQLEDNVGVPLSTYLYTTSLMHCMTVSL 323 >3SM3-A nrPDB Length = 235 Score = 49.8 bits (117), Expect = 1e-06, Method: Composition-based stats. Identities = 24/115 (20%), Positives = 49/115 (42%), Gaps = 9/115 (7%) Query: 61 VLDVACGTGVDSIMLVEEGFSVTSVDASDKMLKYALKERWNRRHEPAFDKWVIEEANWMT 120 +LD+ CG+G S+ L +G+SVT +D + + ++ A P ++ +A + Sbjct: 34 ILDIGCGSGKISLELASKGYSVTGIDINSEAIRLA----ETAARSPGLNQKTGGKAEFKV 89 Query: 121 LDKDVPQSAEGGFDAVICLGNSFAHLPDCKGDQSEHRLALKNIASMVRAGGLLVI 175 + + FD + +PD K E +K + +++ G L + Sbjct: 90 ENASSLSFHDSSFD-FAVMQAFLTSVPDPK----ERSRIIKEVFRVLKPGAYLYL 139 >4KDR-A nrPDB Length = 223 Score = 49.0 bits (115), Expect = 2e-06, Method: Composition-based stats. Identities = 30/127 (23%), Positives = 52/127 (40%), Gaps = 19/127 (14%) Query: 58 CQRVLDVACGTGVDSIMLVEEGFSVTSVDASDKMLKYA-LKERWNRRHEPAFDKWVIEEA 116 ++VLDV CG G+ + + EG +VT +D + L+ A L + + V E A Sbjct: 63 GKKVLDVGCGGGILAESMAREGATVTGLDMGFEPLQVAKLHALESGIQVDYVQETVEEHA 122 Query: 117 NWMTLDKDVPQSAEGGFDAVICLGNSFAHLPDCKGDQSEHRLALKNIASMVRAGGLLVID 176 G +D V C+ H+PD + ++ A +V+ GG + Sbjct: 123 A----------KHAGQYDVVTCM-EMLEHVPDPQS-------VVRACAQLVKPGGDVFFS 164 Query: 177 HRNYDHI 183 N + + Sbjct: 165 TLNRNGV 171 >4KDC-A nrPDB Length = 246 Score = 48.7 bits (114), Expect = 3e-06, Method: Composition-based stats. Identities = 30/123 (24%), Positives = 50/123 (40%), Gaps = 19/123 (15%) Query: 58 CQRVLDVACGTGVDSIMLVEEGFSVTSVDASDKMLKYA-LKERWNRRHEPAFDKWVIEEA 116 ++VLDV CG G+ + + EG +VT +D + L+ A L + + V E A Sbjct: 63 GKKVLDVGCGGGILAESMAREGATVTGLDMGFEPLQVAKLHALESGIQVDYVQETVEEHA 122 Query: 117 NWMTLDKDVPQSAEGGFDAVICLGNSFAHLPDCKGDQSEHRLALKNIASMVRAGGLLVID 176 G +D V C+ H+PD + ++ A +V+ GG + Sbjct: 123 A----------KHAGQYDVVTCM-EMLEHVPDPQS-------VVRACAQLVKPGGDVFFS 164 Query: 177 HRN 179 N Sbjct: 165 TLN 167 >3MGG-A nrPDB Length = 276 Score = 48.3 bits (113), Expect = 4e-06, Method: Composition-based stats. Identities = 32/161 (19%), Positives = 60/161 (37%), Gaps = 31/161 (19%) Query: 21 QYADGEAARVWQLYIGDTRSRTAEYKAWLLGLLRQH----GCQRVLDVACGTGVDSIMLV 76 +Y G + R R +E L LL +VL+ CG G +++L Sbjct: 5 EYVHGYSER--------EALRLSEQAETLEKLLHHDTVYPPGAKVLEAGCGIGAQTVILA 56 Query: 77 EEGFS--VTSVDASDKMLKYALKERWNRRHEPAFDKWVIEEANWMTLDKDVPQSAEGGFD 134 + +TS+D S + L+ A + +AN +L + + FD Sbjct: 57 KNNPDAEITSIDISPESLEKARENTEKN----GIKNVKFLQANIFSLPFE-----DSSFD 107 Query: 135 AVICLGNSFAHLPDCKGDQSEHRLALKNIASMVRAGGLLVI 175 + + HL + ALK++ +++ GG + + Sbjct: 108 HIF-VCFVLEHLQSPEE-------ALKSLKKVLKPGGTITV 140 >3L8D-A nrPDB Length = 242 Score = 47.5 bits (111), Expect = 6e-06, Method: Composition-based stats. Identities = 25/143 (17%), Positives = 54/143 (37%), Gaps = 20/143 (13%) Query: 27 AARVWQLYIGDT-----RSRTAEYKAWLLGLLRQHGCQR--VLDVACGTGVDSIMLVEEG 79 A + W + ++ ++ Q+ + VLDV CG G + L G Sbjct: 16 AEKKWDSSAEFWNQNSQEMWDSGSRSTIIPFFEQYVKKEAEVLDVGCGDGYGTYKLSRTG 75 Query: 80 FSVTSVDASDKMLKYALKERWNRRHEPAFDKWVIEEANWMTLDKDVPQSAEGGFDAVICL 139 + VD S+ M++ + R E ++ + + + + + F+A++ + Sbjct: 76 YKAVGVDISEVMIQKGKE-----RGEGPDLSFIKGDLSSLPFENE-------QFEAIMAI 123 Query: 140 GNSFAHLPDCKGDQSEHRLALKN 162 NS + +E + LK+ Sbjct: 124 -NSLEWTEEPLRALNEIKRVLKS 145 >4PNE-A nrPDB Length = 302 Score = 47.5 bits (111), Expect = 6e-06, Method: Composition-based stats. Identities = 33/159 (20%), Positives = 58/159 (36%), Gaps = 21/159 (13%) Query: 20 DQYADGEAARVWQLYIGDTRSRTAEYKAWLLGLLRQH----GCQRVLDVACGTGVDSIML 75 + A G A + D R+ + L L+ + G R+LDV CGTG ++ + Sbjct: 51 NSVAGGPCAIHHGYWENDGRASWQQAADRLTDLVAERTVLDGGVRLLDVGCGTGQPALRV 110 Query: 76 V-EEGFSVTSVDASDKMLKYALKERWNRRHEPAFDKWVIEEANWMTLDKDVPQSAEGGFD 134 + +T + S + A R D ++ +P + FD Sbjct: 111 ARDNAIQITGITVSQVQVAIAADCARERGLSHRVDFSCVDA-------MSLPYP-DNAFD 162 Query: 135 AVICLGNSFAHLPDCKGDQSEHRLALKNIASMVRAGGLL 173 A A + SE A++ I +++ GG+L Sbjct: 163 A--------AWAMQSLLEMSEPDRAIREILRVLKPGGIL 193 >5JE5-A nrPDB Length = 247 Score = 47.1 bits (110), Expect = 9e-06, Method: Composition-based stats. Identities = 36/149 (24%), Positives = 60/149 (40%), Gaps = 17/149 (11%) Query: 40 SRTAEYKAWLLGLLRQHGCQRVLDVACGTGVDSIMLVEEG-FSVTSVDASDKMLKYALKE 98 ++ A + ++ + VLD+ACG G + G V VD S+KM++ A +E Sbjct: 24 AQRAIEVRTIFHMIGDVSGKSVLDLACGFGFFGREIYRRGAAKVVGVDISEKMIELAREE 83 Query: 99 RWNRRHEPAFDKWVIEEANWMTLDKDVPQSAEGGFDAVICLGNSFAHLPDCKGDQSEHRL 158 +R++ + V + AN L G FD V A L + R Sbjct: 84 --SRKYGDPLEFHVRDVANMEPL---------GQFDLVNA-----AWLFNYADSVENLRK 127 Query: 159 ALKNIASMVRAGGLLVIDHRNYDHILSTG 187 K + + ++ G LV + D L+ G Sbjct: 128 MFKVVRASLKPDGKLVAYTVDPDFSLAKG 156 >2GS9-A nrPDB Length = 211 Score = 46.3 bits (108), Expect = 2e-05, Method: Composition-based stats. Identities = 33/134 (24%), Positives = 46/134 (34%), Gaps = 28/134 (20%) Query: 43 AEYKAWLLGLLRQHGCQRVLDVACGTGVDSIMLVEEGFSVTSVDASDKMLKYALKERWNR 102 AE + L GLL + +L+V GTG L V+ S+ ML R Sbjct: 24 AEEERALKGLL--PPGESLLEVGAGTGYWLRRL--PYPQKVGVEPSEAMLAVG------R 73 Query: 103 RHEPAFDKWVIEEANW-MTLDKDVPQSAEGGFDAVICLGNSFAHLPDCKGDQSEHRLALK 161 R P EA W + +P FD V+ L + L Sbjct: 74 RRAP--------EATWVRAWGEALPFP-GESFDVVL--------LFTTLEFVEDVERVLL 116 Query: 162 NIASMVRAGGLLVI 175 ++R GG LV+ Sbjct: 117 EARRVLRPGGALVV 130 >4QTT-B nrPDB Length = 208 Score = 46.0 bits (107), Expect = 2e-05, Method: Composition-based stats. Identities = 40/161 (24%), Positives = 62/161 (38%), Gaps = 27/161 (16%) Query: 22 YADGEAARVWQLYIGDTRSRTAEYKAWL--LGLLRQHGCQRVLDVACGTGVDSIMLVEEG 79 Y D EA + Y G TR + + K L L LL C +LD+ CG+G+ +L +EG Sbjct: 14 YNDSEAHK----YTGSTRVQHIQAKMTLRALELLNLQPCSFILDIGCGSGLSGEILTQEG 69 Query: 80 FSV-TSVDASDKMLKYALKERWNRRHEPAFDKWVIEEANWMTLDKDVPQS-AEGGFDAVI 137 V +D S ML L E + M D G FDA I Sbjct: 70 DHVWCGLDISPSMLATGLSR--------------ELEGDLMLQDMGTGIPFRAGSFDAAI 115 Query: 138 CLGNSFAHLPDCKGDQSEHR----LALKNIASMVRAGGLLV 174 + ++ L + ++ + + + ++ GG V Sbjct: 116 SI-SAIQWLCNADTSYNDPKQRLMRFFNTLYAALKKGGKFV 155 >5U19-A nrPDB Length = 341 Score = 45.6 bits (106), Expect = 2e-05, Method: Composition-based stats. Identities = 29/144 (20%), Positives = 60/144 (41%), Gaps = 19/144 (13%) Query: 45 YKAWLLGLLRQHGCQRVLDVACGTGVDSIMLVEEGFSVTSVDASDKMLKYALKERWNRRH 104 L+ L+ + G R LD+ CG+GV S++L + SV VD + + + + Sbjct: 131 EADLLIRLMLRRGGARALDMGCGSGVLSLVLADRYESVLGVDVNPRAVALS--------- 181 Query: 105 EPAFDKWVIEEANWMTLDKDVPQSAEGGFDAVIC------LGNSFAHLPDCKGDQSEHRL 158 + + N + D+ + AEG F ++ GN F + + + Sbjct: 182 --RLNAALNGLTNVTFREGDMFEPAEGRFSRIVFNSPTNEEGNEF--VDLLEAGEPILET 237 Query: 159 ALKNIASMVRAGGLLVIDHRNYDH 182 +N+ + +GG++ ++ D+ Sbjct: 238 FFRNVPRKLESGGIVEVNLAMNDY 261 >4NEC-A nrPDB Length = 264 Score = 44.8 bits (104), Expect = 5e-05, Method: Composition-based stats. Identities = 33/148 (22%), Positives = 52/148 (35%), Gaps = 21/148 (14%) Query: 61 VLDVACGTGVDSIMLVEEGFSVTSVDASDKMLKYALKERWNRRHEPAFD----------- 109 VLD CGTG D++ L G++VT +D S + A + R F+ Sbjct: 63 VLDAGCGTGEDALHLAGLGYAVTGLDLSPTAISVARDKADARGLGAVFEVADALDLTGWE 122 Query: 110 ---KWVIEEANWMTLDKDVPQSAEGGFDAVICLGNSFAHLPD-----CKGDQSEHRLALK 161 VI+ T + D ++ C + AH+ Q+ A+ Sbjct: 123 ERFDTVIDSGLAHTFEGDRLRAYATALHRA-CRPGAVAHILSISDRGSAEMQARLAEAID 181 Query: 162 NIASMVRAGGLLVIDHRNYDHILSTGCA 189 I + + R+ DH L G A Sbjct: 182 EIPAPLPDDDESPTLKRSADH-LRDGFA 208 >1RI1-A nrPDB Length = 298 Score = 44.4 bits (103), Expect = 6e-05, Method: Composition-based stats. Identities = 37/159 (23%), Positives = 60/159 (37%), Gaps = 13/159 (8%) Query: 46 KAWLLGLLRQHGCQRVLDVACGTGVDSIMLVEEGF-SVTSVDASDKMLKYALKERWNRRH 104 KA L+ L + G VLD+ CG G D + G VD ++ + A N + Sbjct: 54 KACLIRLYTKRG-DSVLDLGCGKGGDLLKYERAGIGEYYGVDIAEVSINDARVRARNMKR 112 Query: 105 EPAFDKWVIEEANWMTLDKDVPQSAEGGFDAVICLGNSFAHLPDCKGDQSEHRLALKNIA 164 + D+ + FD + + F+ +S +A +NIA Sbjct: 113 RFKVFFRAQDSYGRHM---DLGK----EFDVI---SSQFSFHYAFSTSES-LDIAQRNIA 161 Query: 165 SMVRAGGLLVIDHRNYDHILSTGCAPPGKNIYYKSDLTK 203 +R GG ++ + D IL N +YK +L K Sbjct: 162 RHLRPGGYFIMTVPSRDVILERYKQGRMSNDFYKIELEK 200 >6MRO-A nrPDB Length = 194 Score = 43.3 bits (100), Expect = 1e-04, Method: Composition-based stats. Identities = 32/145 (22%), Positives = 54/145 (37%), Gaps = 17/145 (11%) Query: 31 WQLYIGDTRSRTAEYKAWLLGLLRQHG---CQRVLDVACGTGVDSIMLVEEGFSVTSVDA 87 W T ++ L + G R LD+ CG G ++IML + G VT +D Sbjct: 3 WDEVYKGTPPWDIDHPQPAFQALIESGEIRPGRALDIGCGRGENAIMLAKNGCDVTGIDL 62 Query: 88 SDKMLKYALKERWNRRHEPAFDKWVIEEANWMTLDKDVPQSAEGGFDAVICLGNSFAHLP 147 + + + + V N + +D+ E FD VI G L Sbjct: 63 AK--RAISDAKAKAIERHVKVNFIV---GNVLEMDQLF---TEDEFDIVIDSG-----LF 109 Query: 148 DCKGDQSEHRLALKNIASMVRAGGL 172 D+ E L +++ +++ GG Sbjct: 110 HVITDE-ERLLFTRHVHKVLKEGGK 133 >3E23-A nrPDB Length = 211 Score = 42.1 bits (97), Expect = 3e-04, Method: Composition-based stats. Identities = 30/158 (18%), Positives = 56/158 (35%), Gaps = 25/158 (15%) Query: 25 GEAARVWQLYIGDTRSRTAEYK--AWLLGLLRQHG-CQRVLDVACGTGVDSIMLVEEGFS 81 + Y G+ + A L L + ++L++ CG G + ++ GF Sbjct: 8 AFDDDTLRFYRGNATAYAERQPRSATLTKFLGELPAGAKILELGCGAGYQAEAMLAAGFD 67 Query: 82 VTSVDASDKMLKYALKERWNRRHEPAFDKWVIEEANWMTLDKDVPQSAEGGFDAVICLGN 141 V + D S ++ A +RR + + + A +DAV Sbjct: 68 VDATDGSPELAAEA-----SRRLGRPVRTMLFHQLD-----------AIDAYDAV----- 106 Query: 142 SFAHLPDCKGDQSEHRLALKNIASMVRAGGLLVIDHRN 179 +AH + E LK I ++ GGL +++ Sbjct: 107 -WAHACLLHVPRDELADVLKLIWRALKPGGLFYASYKS 143 >3EGE-A nrPDB Length = 261 Score = 42.1 bits (97), Expect = 3e-04, Method: Composition-based stats. Identities = 24/130 (18%), Positives = 52/130 (40%), Gaps = 29/130 (22%) Query: 49 LLGLLRQHGCQRVLDVACGTGVDSIMLVEEGFSVTSVDASDKMLKYALKERWNRRHEPAF 108 ++ LL + D+ GTG S+ L +G V +V+ S M + A Sbjct: 26 IINLLNLPKGSVIADIGAGTGGYSVALANQGLFVYAVEPSIVMRQQA------------- 72 Query: 109 DKWVIEEANWMT---LDKDVPQSAEGGFDAVICLGNSFAHLPDCKGDQSEHRLALKNIAS 165 V + W T + +P + G +++ + + F+HL + + + Sbjct: 73 --VVHPQVEWFTGYAENLALPDKSVDGVISILAI-HHFSHLE----------KSFQEMQR 119 Query: 166 MVRAGGLLVI 175 ++R G ++++ Sbjct: 120 IIRDGTIVLL 129 >3DP7-A nrPDB Length = 363 Score = 41.7 bits (96), Expect = 3e-04, Method: Composition-based stats. Identities = 26/113 (23%), Positives = 40/113 (35%), Gaps = 13/113 (11%) Query: 26 EAARVWQLYIGDTRSRTAEYKAWLLGLLRQHGCQRVLDVACGTGVDSIMLVEEG--FSVT 83 + + W + D + L + H +R+LD+ TG + V+ VT Sbjct: 151 QVQKSW--FGFDHFYSDQSFGKALEIVFSHHP-KRLLDIGGNTGKWATQCVQYNKEVEVT 207 Query: 84 SVDASDKMLKYALKERWNRRHEPAFDKWVIEEANWMTLDKDVPQSAEGGFDAV 136 VD ++ + E I LD+DVP GFDAV Sbjct: 208 IVDLPQQLEMMRKQTAGLSGSER------IHGHGANLLDRDVPFPT--GFDAV 252 >6G4W-q nrPDB Length = 281 Score = 41.7 bits (96), Expect = 4e-04, Method: Composition-based stats. Identities = 34/158 (21%), Positives = 57/158 (36%), Gaps = 22/158 (13%) Query: 17 GLPDQYADGEAARVWQLYIGDTRSRTAEYKAW-----LLGLLRQHGCQRVLDVACGTGVD 71 G P+ + D AR Y+ ++R + + LL L C +LD+ CGTG+ Sbjct: 12 GPPELFYDETEARK---YVRNSRMIDIQTRMAGRALELLYLPENKPCY-LLDIGCGTGLS 67 Query: 72 SIMLVEEGFSVTSVDASDKMLKYALKERWNRRHEPAFDKWVIEEANWMTLDKDVPQSAEG 131 L +EG +D S ML A D+ + + + + +P G Sbjct: 68 GSYLSDEGHYWVGLDISPAMLDEA------------VDREIEGDLLLGDMGQGIPFK-PG 114 Query: 132 GFDAVICLGNSFAHLPDCKGDQSEHRLALKNIASMVRA 169 FD I + K ++ + AS+ Sbjct: 115 TFDGCISISAVQWLCNANKKSENPAKRLYCFFASLFSV 152 >4INE-A nrPDB Length = 454 Score = 41.3 bits (95), Expect = 4e-04, Method: Composition-based stats. Identities = 26/123 (21%), Positives = 44/123 (35%), Gaps = 22/123 (17%) Query: 56 HGCQRVLDVACGTGVDSIMLVEE-GFSVTSVDASDKMLKYALKERWNRRHEPAFDKWVIE 114 Q +LD+ G G + + +E G V +D S ML AL+ R HE + Sbjct: 240 KPGQTMLDIGVGIGGGARQVADEFGVHVHGIDLSSNMLAIALE----RLHEEKDSRVKYS 295 Query: 115 EANWMTLDKDVPQSAEGGFDAVICLGNSFAHLP--DCKGDQSEHRLALKNIASMVRAGGL 172 + + + NSF ++ DC + I ++ GG Sbjct: 296 ITDALVYQFE---------------DNSFDYVFSRDCIQHIPDTEKLFSRIYKALKPGGK 340 Query: 173 LVI 175 ++I Sbjct: 341 VLI 343 >3JWJ-A nrPDB Length = 202 Score = 41.3 bits (95), Expect = 5e-04, Method: Composition-based stats. Identities = 40/203 (19%), Positives = 72/203 (35%), Gaps = 15/203 (7%) Query: 49 LLGLLRQHGCQRVLDVACGTGVDS-IMLVEEGFS-VTSVDASDKMLKYALKERWNRRHEP 106 ++ L+Q +RV+D+ CG G I+L + F +T VD S + L+ A + R Sbjct: 11 VVAALKQSNARRVIDLGCGQGNLLKILLKDSFFEQITGVDVSYRSLEIAQERLDRLRLPR 70 Query: 107 AFDKWVIEEANWMTLDKDVPQSAEGGFDAVICLGNSFAHLPDCKGDQSEHRLALKNIASM 166 ++W + L G+DA + HL + L A Sbjct: 71 --NQWERLQLIQGALTYQ--DKRFHGYDAATVI-EVIEHLDLSR--LGAFERVLFEFAQ- 122 Query: 167 VRAGGLLVIDHRNYDHILSTGCAPPGKNIYYKSDLTKDVTTSVLIVNNKAHMVTLDYTVQ 226 ++++ N ++ + P GK + D + T S Y VQ Sbjct: 123 ---PKIVIVTTPNIEYNVKFANLPAGKLRH--KDHRFEWTRSQFQNWANKITERFAYNVQ 177 Query: 227 VPGAGQDGSPGLSKFRLSYYPHC 249 G+ S +++ + H Sbjct: 178 FQPIGEADPEVGSPTQMAVFIHR 200 >4HTF-A nrPDB Length = 285 Score = 41.0 bits (94), Expect = 6e-04, Method: Composition-based stats. Identities = 40/181 (22%), Positives = 70/181 (38%), Gaps = 19/181 (10%) Query: 8 TRSLGVAAEGLPDQYADGEAARVWQLYIGDTRSRTAEYKAW--LLGLLRQHGCQ--RVLD 63 T +L + + D+ D A + + G T+ + + W L +L + G Q RVLD Sbjct: 15 TENLYFQSNAMQDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLD 74 Query: 64 VACGTGVDSIMLVEEGFSVTSVDASDKMLKYALKERWNRRHEPAFDKWVIEEANWMTLDK 123 G G +I + E G V D S +M+ A + + + A + Sbjct: 75 AGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQF-IHCAAQDVASHL 133 Query: 124 DVPQSAEGGFDAVICLGNSFAHLPDCKGDQSEHRLALKNIASMVRAGGLLVIDHRNYDHI 183 + P F AV+ ++ R L+ + S++R GG+L + N + Sbjct: 134 ETP-VDLILFHAVL-------------EWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGL 179 Query: 184 L 184 L Sbjct: 180 L 180 >4KRI-A nrPDB Length = 433 Score = 41.0 bits (94), Expect = 6e-04, Method: Composition-based stats. Identities = 29/121 (23%), Positives = 45/121 (37%), Gaps = 22/121 (18%) Query: 58 CQRVLDVACGTGVDSIMLV-EEGFSVTSVDASDKMLKYALKERWNRRHEPAFDKWVIEEA 116 QR+LD+ G G + E G V VD S ML AL ER ++ + V + Sbjct: 223 GQRMLDIGVGIGGGARQAASEFGLQVHGVDLSTNMLAVAL-ERVHKEKDARVTYAVCDAC 281 Query: 117 NWMTLDKDVPQSAEGGFDAVICLGNSFAHLP--DCKGDQSEHRLALKNIASMVRAGGLLV 174 + F+ NSF ++ DC + I ++ GG ++ Sbjct: 282 EYE-------------FEP-----NSFDYVFSRDCIQHIKDTDKLFSRIYRALKPGGKVL 323 Query: 175 I 175 I Sbjct: 324 I 324 >5BP9-A nrPDB Length = 281 Score = 40.6 bits (93), Expect = 8e-04, Method: Composition-based stats. Identities = 24/127 (18%), Positives = 48/127 (37%), Gaps = 22/127 (17%) Query: 61 VLDVACGTGVDSIMLVEEGFSVTSVDASDKMLKY-ALKERWNRRHEPAFDKWVIEEANWM 119 +LDV G+G ++ L E G V+++D S ++ L+ + R FD Sbjct: 105 ILDVGAGSGCHALALQESGKEVSAIDISPLSVEVMKLRGVKDARQVNLFD---------- 154 Query: 120 TLDKDVPQSAEGGFDAVICLGNSFAHLPDCKGDQSEHRLALKNIASMVRAGGLLVIDHRN 179 + FD ++ L N G L + + ++R G +++D + Sbjct: 155 -------ERFAATFDTILMLMNG----SGIIGRLENMPLFFRKMKQLLRPDGCILMDSSD 203 Query: 180 YDHILST 186 ++ Sbjct: 204 LRYLFED 210 >3LCC-A nrPDB Length = 235 Score = 40.6 bits (93), Expect = 0.001, Method: Composition-based stats. Identities = 25/152 (16%), Positives = 48/152 (31%), Gaps = 17/152 (11%) Query: 24 DGEAARVWQLYIGDT-RSRTAEYKAWLLGLLRQHGCQRVLDVACGTGVDSIMLVEEGFSV 82 +G + W+ I + R L+ R L CG G D + + V Sbjct: 33 EGGWEKCWEEEITPWDQGRATPLIVHLVDT-SSLPLGRALVPGCGGGHDVVAMASPERFV 91 Query: 83 TSVDASDKMLKYALKERWNRRHEPAFDKWVIEEANWMTLDKDVPQSAEGGFDAVICLGNS 142 +D S+ L A + + F + W + FD + Sbjct: 92 VGLDISESALAKANETYGSSPKAEYFSFVKEDVFTWRPTEL---------FDLI------ 136 Query: 143 FAHLPDCKGDQSEHRLALKNIASMVRAGGLLV 174 F ++ C + K++ +++ G L+ Sbjct: 137 FDYVFFCAIEPEMRPAWAKSMYELLKPDGELI 168 >5WP5-A nrPDB Length = 491 Score = 39.4 bits (90), Expect = 0.002, Method: Composition-based stats. Identities = 29/121 (23%), Positives = 43/121 (35%), Gaps = 19/121 (15%) Query: 56 HGCQRVLDVACGTGVDSIMLVEEG-FSVTSVDASDKMLKYALKERWNRRHEPAFDKWVIE 114 Q+VLDV CG G + E V +D S M+ +AL+ V Sbjct: 281 KPGQKVLDVGCGIGGGDFYMAENFDVHVVGIDLSVNMISFALE------RAIGLKCSVEF 334 Query: 115 EANWMTLDKDVPQSAEGGFDAVICLGNSFAHLPDCKGDQSEHRLALKNIASMVRAGGLLV 174 E T K P FD VI ++ H+ D + ++ GG ++ Sbjct: 335 EVADCT-TKTYPD---NSFD-VIYSRDTILHIQDKPA-------LFRTFFKWLKPGGKVL 382 Query: 175 I 175 I Sbjct: 383 I 383 >5WP4-A nrPDB Length = 491 Score = 39.4 bits (90), Expect = 0.002, Method: Composition-based stats. Identities = 29/121 (23%), Positives = 44/121 (36%), Gaps = 19/121 (15%) Query: 56 HGCQRVLDVACGTGVDSIMLVEEG-FSVTSVDASDKMLKYALKERWNRRHEPAFDKWVIE 114 Q+VLDV CG G + E+ V +D S M+ +AL+ V Sbjct: 281 KPGQKVLDVGCGIGGGDFYMAEKFDVHVVGIDLSVNMISFALE------RAIGLSCSVEF 334 Query: 115 EANWMTLDKDVPQSAEGGFDAVICLGNSFAHLPDCKGDQSEHRLALKNIASMVRAGGLLV 174 E T K P FD VI ++ H+ D + ++ GG ++ Sbjct: 335 EVADCT-TKHYPD---NSFD-VIYSRDTILHIQDKPA-------LFRTFFKWLKPGGKVL 382 Query: 175 I 175 I Sbjct: 383 I 383 >3OU6-A nrPDB Length = 218 Score = 39.0 bits (89), Expect = 0.002, Method: Composition-based stats. Identities = 18/78 (23%), Positives = 34/78 (43%), Gaps = 3/78 (3%) Query: 61 VLDVACGTGVDSIMLVEEGFSVTSVDASDKMLKYALKERWNR---RHEPAFDKWVIEEAN 117 VL++A GTG + L VT++D S +M+ A + + R + FD + + Sbjct: 50 VLELASGTGYWTRHLSGLADRVTALDGSAEMIAEAGRHGLDNVEFRQQDLFDWTPDRQWD 109 Query: 118 WMTLDKDVPQSAEGGFDA 135 + + + F+A Sbjct: 110 AVFFAHWLAHVPDDRFEA 127 >5Z9O-A nrPDB Length = 399 Score = 39.0 bits (89), Expect = 0.003, Method: Composition-based stats. Identities = 27/128 (21%), Positives = 51/128 (39%), Gaps = 17/128 (13%) Query: 49 LLGLLRQHGCQRVLDVACGTGVDSIMLV-EEGFSVTSVDASDKMLKYALKERWNRRHEPA 107 +L L + +LD+ CG G + E G VT V S++ K K Sbjct: 157 ILNKLHPEKGKTLLDIGCGWGTLMLTAAKEYGLKVTGVTLSEEQYKLVQK--------KI 208 Query: 108 FDKWVIEEANWMTLDKDVPQSAEGGFDAVICLGNSFAHLPDCKGDQSEHRLALKNIASMV 167 +D+ + + A +D + + +D V +G F H+ + K++A + Sbjct: 209 YDEGLEDVAEVKL--EDYRELGDQQWDYVTSVG-MFEHVGSENLGE-----YFKDVAKYL 260 Query: 168 RAGGLLVI 175 + G+ +I Sbjct: 261 KNDGVALI 268 >4QDJ-A nrPDB Length = 238 Score = 38.6 bits (88), Expect = 0.003, Method: Composition-based stats. Identities = 26/96 (27%), Positives = 35/96 (36%), Gaps = 11/96 (11%) Query: 57 GCQRVLDVACGTGVDSIMLVEEGFSVTSVDASDKMLKYALKERWNRRHEPAFDKWVIEEA 116 V D CG G SI L + G V D S+KM+ A ++ V+ Sbjct: 62 PGLLVCDAGCGVGSLSIPLAQAGALVYGSDISEKMVGEAQQKAQE----------VLAYG 111 Query: 117 NWMTLDKDVPQSAEGGFDAVICLGNSFAHLPDCKGD 152 N T G +D VICL + H P + Sbjct: 112 NQPTFMTQDLAQLGGKYDTVICL-DVLIHYPTEEAS 146 >3BKW-A nrPDB Length = 243 Score = 38.6 bits (88), Expect = 0.003, Method: Composition-based stats. Identities = 29/135 (21%), Positives = 44/135 (32%), Gaps = 22/135 (16%) Query: 42 TAEYKAWLLGLLRQHGCQRVLDVACGTGVDSIMLVEEGFS-VTSVDASDKMLKYALKERW 100 AE+ A L +L + G R++D+ CG G E G S V +D S+KML A Sbjct: 29 AAEWPA-LRAMLPEVGGLRIVDLGCGFGWFCRWAHEHGASYVLGLDLSEKMLARARAAG- 86 Query: 101 NRRHEPAFDKWVIEEANWMTLDKDVPQSAEGGFDAVICLGNSFAHLPDCKGDQSEHRLAL 160 + D D + FD A+ + Sbjct: 87 -----------PDTGITYERADLDKLHLPQDSFD--------LAYSSLALHYVEDVARLF 127 Query: 161 KNIASMVRAGGLLVI 175 + + + GG V Sbjct: 128 RTVHQALSPGGHFVF 142 >2I6G-A nrPDB Length = 199 Score = 38.6 bits (88), Expect = 0.003, Method: Composition-based stats. Identities = 16/65 (24%), Positives = 27/65 (41%), Gaps = 4/65 (6%) Query: 60 RVLDVACGTGVDSIMLVEEGFSVTSVDASDKMLKYALKERWNRRHEPAFDKWVIEEANWM 119 R LD+ CG G +S+ L G+ VT+ D + ++ + D + + Sbjct: 34 RTLDLGCGNGRNSLYLAANGYDVTAWDKNPA----SMANLERIKAAEGLDNLQTDLVDLN 89 Query: 120 TLDKD 124 TL D Sbjct: 90 TLTFD 94 >5EVJ-A nrPDB Length = 387 Score = 38.6 bits (88), Expect = 0.003, Method: Composition-based stats. Identities = 29/118 (24%), Positives = 42/118 (35%), Gaps = 12/118 (10%) Query: 60 RVLDVACGTGVD---SIMLVEEGFSVTSVDASDKMLKYALK-ERWNRRHEPAFDKWVIEE 115 RVLD+ G+G D + LV E SVT VD + L+ A+ R + + K + Sbjct: 86 RVLDLGAGSGRDAYVAAKLVGEKGSVTGVDMTPAQLEVAISHADAYARDKLGYGKSNMTF 145 Query: 116 ANWMTLDKDVPQSAEGGFDAVICLGNSFAHLPDCKGDQSEHRLALKNIASMVRAGGLL 173 D + FD VI PD L ++ GG + Sbjct: 146 IQGEIEYLDRAGLEDSSFDLVISNC-VINLSPDKA-------RVLSEAYRVLAPGGEM 195 >2B3T-A nrPDB Length = 276 Score = 37.9 bits (86), Expect = 0.005, Method: Composition-based stats. Identities = 29/181 (16%), Positives = 59/181 (32%), Gaps = 25/181 (13%) Query: 16 EGLPDQYADGEAARVWQLYIGDTRSRTAEYKAW------LLGLLRQHGCQRVLDVACGTG 69 +G P + G W L + + + L L + C R+LD+ GTG Sbjct: 64 DGEPIAHLTG-VREFWSLPLFVSPATLIPRPDTECLVEQALARLPEQPC-RILDLGTGTG 121 Query: 70 VDSIMLVEEGFS--VTSVDASDKMLKYALKERWNRRHEPAFDKWVIEEANWMTLDKDVPQ 127 ++ L E + +VD + A + A I +++W + Sbjct: 122 AIALALASERPDCEIIAVDRMPDAVSLAQR----NAQHLAIKNIHILQSDWFSALAGQQF 177 Query: 128 -------SAEGGFDAVICLGNS----FAHLPDCKGDQSEHRLALKNIASMVRAGGLLVID 176 D + G+ L ++ ++ + + +GG L+++ Sbjct: 178 AMIVSNPPYIDEQDPHLQQGDVRFEPLTALVAADSGMADIVHIIEQSRNALVSGGFLLLE 237 Query: 177 H 177 H Sbjct: 238 H 238 >2P35-A nrPDB Length = 259 Score = 37.5 bits (85), Expect = 0.008, Method: Composition-based stats. Identities = 26/82 (31%), Positives = 37/82 (45%), Gaps = 9/82 (10%) Query: 25 GEAARVWQLYIGDTRSRTAEYKAWLLGLLRQHGCQRVL---DVACGTGVDSIMLVEE-GF 80 G A Q Y+ RT + LL Q +RVL D+ CG G + +L + G Sbjct: 2 GHMAWSAQQYLKFEDERTRPARD----LLAQVPLERVLNGYDLGCGPGNSTELLTDRYGV 57 Query: 81 SV-TSVDASDKMLKYALKERWN 101 +V T +D+ D ML+ A N Sbjct: 58 NVITGIDSDDDMLEKAADRLPN 79 >3HNR-A nrPDB Length = 220 Score = 37.1 bits (84), Expect = 0.009, Method: Composition-based stats. Identities = 37/177 (20%), Positives = 68/177 (38%), Gaps = 28/177 (15%) Query: 11 LGVAAEGLPDQYADGEAARVWQLYIGDTRSRTAEYKAWLLGLLRQHGCQRVLDVACGTGV 70 +G GL D++A + V I A Y+ L ++ + VL+ GTG Sbjct: 1 MGTEFNGLFDEWAHTYDSFVQGEDIQYKEVF-AHYEDILEDVVNKSFGN-VLEFGVGTGN 58 Query: 71 DSIMLVEEGFSVTSVDASDKMLKYALKERWNRRHEPAFDKWVIEEANWMTLDKDVPQSAE 130 + L+ G +V ++ S +M A E ++ I E ++++ + Sbjct: 59 LTNKLLLAGRTVYGIEPSREMRMIA--------KEKLPKEFSITEGDFLSFE------VP 104 Query: 131 GGFDAVICLGNSFAHLPDCKGDQSEHRLALKNIASMVRAGGLLVI------DHRNYD 181 D ++ +F HL D E +A+ + ++ GG +V D YD Sbjct: 105 TSIDTIVS-TYAFHHLTDD-----EKNVAIAKYSQLLNKGGKIVFADTIFADQDAYD 155 >5MGZ-A nrPDB Length = 236 Score = 37.1 bits (84), Expect = 0.010, Method: Composition-based stats. Identities = 30/156 (19%), Positives = 59/156 (37%), Gaps = 18/156 (11%) Query: 21 QYADGEAARVWQLYIGDTRSRTAEYKAWLLGLLRQHGCQRVLDVACGTGVDSIMLVEEGF 80 + G A + R E+ L+G G Q V+D+ CG+G ++L Sbjct: 4 EAITGSEAEAFHRMGSQASHRYDEFVDLLVGAGIADG-QTVVDLCCGSGELEVILSSRFP 62 Query: 81 S--VTSVDASDKMLKYALKERWNRRHEPAFDKWVIEEANWMTLDKDVPQSAEGGFDAVIC 138 S + VD S+ M++ A R + ++ +A + +D+ A+ ++ Sbjct: 63 SLNLVGVDLSEDMVRIA---REYAAEQGKALEFRHGDAQLLAGMEDLAGKAD-----LVV 114 Query: 139 LGNSFAHLPDCKGDQSEHRLALKNIASMVRAGGLLV 174 N+F L A + + + GG ++ Sbjct: 115 SRNAFHRLTRLPA-------AFDTMLRLAKPGGAVL 143 >6DCC-A nrPDB Length = 309 Score = 36.7 bits (83), Expect = 0.011, Method: Composition-based stats. Identities = 15/68 (22%), Positives = 32/68 (47%), Gaps = 2/68 (2%) Query: 109 DKWVIEEANWMTLDKDVPQSAEGGFDAVICLGNSFAHLPDCKGDQSEHRLALKNIASMVR 168 + V N++ D+ ++ +D V+CL + + GD+ + + I +R Sbjct: 171 NNVVFVTGNYVLDRDDLVEAQTPEYDVVLCLSLT-KWVHLNWGDEG-LKRMFRRIYRHLR 228 Query: 169 AGGLLVID 176 GG+LV++ Sbjct: 229 PGGILVLE 236 >2PJD-A nrPDB Length = 343 Score = 36.7 bits (83), Expect = 0.014, Method: Composition-based stats. Identities = 29/130 (22%), Positives = 42/130 (32%), Gaps = 19/130 (14%) Query: 49 LLGLLRQHGCQRVLDVACGTGVDSIMLVEEGFSV--TSVDASDKMLKYALKERWNRRHEP 106 LL L H +VLDV CG GV S+ + T D S ++ + E Sbjct: 188 LLSTLTPHTKGKVLDVGCGAGVLSVAFARHSPKIRLTLCDVSAPAVEASRATLAANGVEG 247 Query: 107 AFDKWVIEEANWMTLDKDVPQSAEGGFDAVICLGNSFAHLPDCKGDQSEHRLAL-KNIAS 165 +V +G FD +I S D + L + Sbjct: 248 EV------------FASNVFSEVKGRFDMII----SNPPFHDGMQTSLDAAQTLIRGAVR 291 Query: 166 MVRAGGLLVI 175 + +GG L I Sbjct: 292 HLNSGGELRI 301 >5E72-A nrPDB Length = 346 Score = 36.3 bits (82), Expect = 0.015, Method: Composition-based stats. Identities = 28/119 (23%), Positives = 47/119 (39%), Gaps = 10/119 (8%) Query: 59 QRVLDVACGTGVDSIMLVEEGFSVTSVDASDKMLKYALKERWNRRHEPAFDKWVIEEANW 118 + +LD G G I G V VD +M++ A + ++ + Sbjct: 181 REILDPFMGAGGILIEAGLLGLRVYGVDIRPEMVEGA----ETNLKHYGVRDYTLKLGDA 236 Query: 119 MTLDKDVPQSAEGGFDAVIC--LGNSFAHLPDCKGDQSEHRLALKNIASMVRAGGLLVI 175 L+ P F+AV + A L K D+ +R AL++I +++ GG L I Sbjct: 237 TRLEDLFPDK---KFEAVATDPPYGTAATLAGRKRDEL-YRKALRSIYNVLEDGGRLAI 291 >4HGY-A nrPDB Length = 276 Score = 36.3 bits (82), Expect = 0.015, Method: Composition-based stats. Identities = 28/123 (22%), Positives = 46/123 (37%), Gaps = 16/123 (13%) Query: 59 QRVLDVACGTGVDSIMLVEEGFSVTSVDASDKMLKYALKERWNRRHEPAFDKWVIEEANW 118 + VL++ GTG + L + G V V++S+ ML K R P + V N+ Sbjct: 64 RPVLELGVGTGRVAFPLADLGVEVHGVESSEPMLD---KLREKAAAHPNGNLVVPVLGNF 120 Query: 119 MTLD--KDVPQSAEGGFDAVICLGNSFAHLPDCKGDQSEHRLALKNIASMVRAGGLLVID 176 LD + F+ + CL Q E ++ ++ GG V+ Sbjct: 121 AKLDLGEQRYSVVFAAFNTLFCLLG-----------QDEQIDCMRQARELLEPGGTFVVQ 169 Query: 177 HRN 179 N Sbjct: 170 CLN 172 >5M58-A nrPDB Length = 230 Score = 36.3 bits (82), Expect = 0.016, Method: Composition-based stats. Identities = 16/53 (30%), Positives = 25/53 (47%), Gaps = 2/53 (3%) Query: 58 CQRVLDVACGTGVDSIMLVEEGFS--VTSVDASDKMLKYALKERWNRRHEPAF 108 Q V+D+ CG+G I+L S + VD S+ M++ A + E F Sbjct: 40 GQTVVDLCCGSGELEIILTSRFPSLNLVGVDLSEDMVRIARDYAAEQGKELEF 92 >5I2H-A nrPDB Length = 364 Score = 36.3 bits (82), Expect = 0.017, Method: Composition-based stats. Identities = 30/166 (18%), Positives = 59/166 (35%), Gaps = 21/166 (12%) Query: 27 AARVWQLYIGDTRSRTAEYKAWLLGLLRQHGCQRVLDVACGTGVDSIMLVEEGFSVTSVD 86 A R W + A +L + +LDVA G+G+ ++ ++++ + + Sbjct: 166 AGRAWNVAPRFADVLPAGQPGKILKDNSGSSGRVLLDVAGGSGIYTMAVLQKYPTWRGII 225 Query: 87 AS-DKMLKYALKERWNRRHEPAFDKWVIEEANWMTLDKDVPQSAEGGFDAVICLGNSFAH 145 ++LK A + + + A M +D P I L N Sbjct: 226 FDRPEVLKIAAELAE----QTGVRDRLELHAGDMWVD---PFPPADD----ILLSNVL-- 272 Query: 146 LPDCKGDQSEHRLALKNIASMVRAGGLLVIDHRNYDHILSTGCAPP 191 D+ + + S + GG L+I +D +L++ P Sbjct: 273 ---HDWDRPQCARLVAKATSGLPEGGRLLI----HDVLLNSDLTGP 311 >1VBF-A nrPDB Length = 231 Score = 35.9 bits (81), Expect = 0.019, Method: Composition-based stats. Identities = 17/52 (32%), Positives = 28/52 (53%) Query: 46 KAWLLGLLRQHGCQRVLDVACGTGVDSIMLVEEGFSVTSVDASDKMLKYALK 97 ++L L H Q+VL++ G G + ++ E V SV+ ++KM YA K Sbjct: 59 GIFMLDELDLHKGQKVLEIGTGIGYYTALIAEIVDKVVSVEINEKMYNYASK 110 >4FS8-A nrPDB Length = 383 Score = 35.6 bits (80), Expect = 0.024, Method: Composition-based stats. Identities = 33/137 (24%), Positives = 52/137 (37%), Gaps = 14/137 (10%) Query: 58 CQRVLDVACGTGVD----SIMLVEEGFSVTSVDASDKMLKYALKERWNRRHE--PAFDKW 111 VLD+ CGTG D S ++ E G V VD D L+ A K + + + Sbjct: 84 GATVLDLGCGTGRDVYLASKLVGEHG-KVIGVDMLDNQLEVARKYVEYHAEKFFGSPSRS 142 Query: 112 VIEEANWMTLDKDVPQSAEGGFDAVICLGNSFAHLPDCKGDQSEHRLAL-KNIASMVRAG 170 + + + +V + + +C + S ++LAL K I ++R G Sbjct: 143 NVRFLKGFIENLATAEPEGVPDSSVDIV------ISNCVCNLSTNKLALFKEIHRVLRDG 196 Query: 171 GLLVIDHRNYDHILSTG 187 G L D LS Sbjct: 197 GELYFSDVYADRRLSEA 213 >2YR0-A nrPDB Length = 263 Score = 35.6 bits (80), Expect = 0.025, Method: Composition-based stats. Identities = 23/114 (20%), Positives = 43/114 (37%), Gaps = 20/114 (17%) Query: 62 LDVACGTGVDSIMLVEEGFSVTSVDASDKMLKYALKERWNRRHEPAFDKWVI-EEANWMT 120 L++ GTG ++ L+ G+ ++DA ML+ R+ D+ V +A+ Sbjct: 44 LELGVGTGRIALPLIARGYRYIALDADAAMLEV------FRQKIAGVDRKVQVVQADARA 97 Query: 121 LDKDVPQSAEGGFDAVICLGNSFAHLPDCKGDQSEHRLALKNIASMVRAGGLLV 174 +P E ++ HL D L +++ GG L+ Sbjct: 98 ----IPLPDESVHGVIVV------HLWHLVPDWP---KVLAEAIRVLKPGGALL 138 >1TPY-A nrPDB Length = 287 Score = 35.2 bits (79), Expect = 0.035, Method: Composition-based stats. Identities = 21/130 (16%), Positives = 40/130 (30%), Gaps = 24/130 (18%) Query: 50 LGLLRQHGCQRVLDVACGTGVDSIM-LVEEGFSVTSVDASD---KMLKYALKERWNRRHE 105 LG L +LD+ CG G + + +V + S ++ + E R Sbjct: 57 LGKLGLQPGMTLLDIGCGWGATMRRAIAQYDVNVVGLTLSKNQAAHVQKSFDEMDTPRDR 116 Query: 106 PAFDKWVIEEANWMTLDKDVPQSAEGGFDAVICLGNSFAHLPDCKGDQSEHRLALKNIAS 165 A W ++ V D ++ +G D D Sbjct: 117 RVLL------AGWEQFNEPV--------DRIVSIGAFEHFGHDRHADF------FARAHK 156 Query: 166 MVRAGGLLVI 175 ++ G+L++ Sbjct: 157 ILPPDGVLLL 166 >3HEM-A nrPDB Length = 302 Score = 34.8 bits (78), Expect = 0.042, Method: Composition-based stats. Identities = 26/126 (20%), Positives = 45/126 (35%), Gaps = 15/126 (11%) Query: 53 LRQHGCQRVLDVACGTGVDSIM-LVEEGFSVTSVDASDKMLKYALKERWNRRHEPAFDKW 111 L +LD+ CG G + E +V + S+ +YA + + K Sbjct: 68 LNLEPGMTLLDIGCGWGSTMRHAVAEYDVNVIGLTLSEN--QYAHDKAMFDEVDSPRRKE 125 Query: 112 VIEEANWMTLDKDVPQSAEGGFDAVICLGNSFAHLPDCKGDQSEHR--LALKNIASMVRA 169 V + + D P D ++ LG +F H D GD R K ++ Sbjct: 126 VRIQG---WEEFDEP------VDRIVSLG-AFEHFADGAGDAGFERYDTFFKKFYNLTPD 175 Query: 170 GGLLVI 175 G +++ Sbjct: 176 DGRMLL 181 >2VS1-A nrPDB Length = 425 Score = 34.8 bits (78), Expect = 0.042, Method: Composition-based stats. Identities = 15/76 (19%), Positives = 31/76 (40%) Query: 58 CQRVLDVACGTGVDSIMLVEEGFSVTSVDASDKMLKYALKERWNRRHEPAFDKWVIEEAN 117 +++LD+ G G I L + GF+V D+++ ++ A + + F+ E + Sbjct: 291 GEKILDMYSGVGTFGIYLAKRGFNVKGFDSNEFAIEMARRNVEINNVDAEFEVASDREVS 350 Query: 118 WMTLDKDVPQSAEGGF 133 D + G Sbjct: 351 VKGFDTVIVDPPRAGL 366 >4KIC-A nrPDB Length = 357 Score = 34.8 bits (78), Expect = 0.043, Method: Composition-based stats. Identities = 22/111 (19%), Positives = 39/111 (35%), Gaps = 7/111 (6%) Query: 61 VLDVACGTGVDSIMLVEEGFSV--TSVDASDKMLKYALKERWNRRHEPAFDKWVIEEANW 118 V D+ G+G I + V VD +D + A KE + + Sbjct: 182 VADLGSGSGERLIQIARRFPGVRGLGVDIADGAIAMAEKEVAAKGFGDQISFV---RGDA 238 Query: 119 MTLDKDVPQSAEGGFDAVIC--LGNSFAHLPDCKGDQSEHRLALKNIASMV 167 T+D+ + D + C +G+ F +C + R A N+ + Sbjct: 239 RTIDQVSARGEFAEVDLLTCFMMGHDFWPRENCVQTLRKLRAAFPNVRRFL 289 >4DZR-A nrPDB Length = 215 Score = 34.8 bits (78), Expect = 0.044, Method: Composition-based stats. Identities = 23/74 (31%), Positives = 30/74 (40%), Gaps = 6/74 (8%) Query: 58 CQRVLDVACGTG--VDSIMLVEEGFSVTSVDASDKMLKYALKERWNRRHEPAFDKWVIEE 115 RV+DV G+G SI L G SVT+VD S L A R N A W + Sbjct: 31 GTRVIDVGTGSGCIAVSIALACPGVSVTAVDLSMDALAVA---RRNAERFGAVVDWAAAD 87 Query: 116 A-NWMTLDKDVPQS 128 W+ + + Sbjct: 88 GIEWLIERAERGRP 101 >1NKV-A nrPDB Length = 256 Score = 34.8 bits (78), Expect = 0.048, Method: Composition-based stats. Identities = 26/135 (19%), Positives = 43/135 (31%), Gaps = 18/135 (13%) Query: 42 TAEYKAWLLGLLRQHGCQRVLDVACGTGVDSIMLV-EEGFSVTSVDASDKMLKYALKERW 100 T E A L +LR R+LD+ G+G + G + T +D S A + Sbjct: 21 TEEKYATLGRVLRMKPGTRILDLGSGSGEMLCTWARDHGITGTGIDMSSLFTAQAKRRAE 80 Query: 101 NRRHEPAFDKWVIEEANWMTLDKDVPQSAEGGFDAVICLGNSFAHLPDCKGDQSEHRLAL 160 + A A D C+G + E Sbjct: 81 ELGVSERVHFIHNDAA---------GYVANEKCDVAACVGA--TWIAGGFAGAEEL---- 125 Query: 161 KNIASMVRAGGLLVI 175 +A ++ GG+++I Sbjct: 126 --LAQSLKPGGIMLI 138 >1UWV-A nrPDB Length = 433 Score = 34.8 bits (78), Expect = 0.049, Method: Composition-based stats. Identities = 23/87 (26%), Positives = 38/87 (43%), Gaps = 9/87 (10%) Query: 53 LRQHGCQRVLDVACGTGVDSIMLVEEGFSVTSVDASDKMLKYALKERWNRRHEPAFDKWV 112 L RVLD+ CG G ++ L + SV V+ +++ + N R + Sbjct: 282 LDVQPEDRVLDLFCGMGNFTLPLATQAASVVGVEGVPALVEKGQQ---NARLNGLQNVTF 338 Query: 113 IEEANWMTLDKDVPQS--AEGGFDAVI 137 E L++DV + A+ GFD V+ Sbjct: 339 YHEN----LEEDVTKQPWAKNGFDKVL 361 >4P7C-A nrPDB Length = 322 Score = 34.4 bits (77), Expect = 0.057, Method: Composition-based stats. Identities = 33/120 (27%), Positives = 54/120 (45%), Gaps = 18/120 (15%) Query: 58 CQRVLDVACGTGVDSIMLVEEGFS-VTSVDASDKMLKYALKERWNRRHEPAFDKWVIEEA 116 +RVLDV CG G ++ G V VD + + + + +R+ P W + A Sbjct: 122 GKRVLDVGCGNGYYQWRMLGAGADSVIGVDPN---WLFFCQFQAMQRYLPDLPAWHLPFA 178 Query: 117 NWMTLDKDVPQSAEGGFDAVICLGNSFAHLPDCKGDQSEHRLALKNIASMVRAGGLLVID 176 +D+P + EG FD V +G + + +H LALK+ + GG LV++ Sbjct: 179 L-----EDLPANLEG-FDTVFSMG-----VLYHRKSPIDHLLALKDC---LVKGGELVME 224 >3MCZ-A nrPDB Length = 352 Score = 34.4 bits (77), Expect = 0.058, Method: Composition-based stats. Identities = 29/154 (18%), Positives = 54/154 (35%), Gaps = 26/154 (16%) Query: 34 YIGDTRSRTAEYKAWL------LGLLRQHG----CQRVLDVACGTGVDSIMLVEEGFSVT 83 + DTR+R A A + + ++ + G + V+D+A G G ++ +T Sbjct: 146 FAHDTRARDAFNDAMVRLSQPMVDVVSELGVFARARTVIDLAGGHGTYLAQVLRRHPQLT 205 Query: 84 SV--DASDKMLKYALKERWNRRHEPAFDKWVIEEANWMTLDKDVPQSAEGGFDAVICLGN 141 D A K + + + + GG V+ L + Sbjct: 206 GQIWDL-PTTRDAARKTIHAHDLGGRVEFFEKNLLDARNFE--------GGAADVVMLND 256 Query: 142 SFAHLPDCKGDQSEHRLALKNIASMVRAGGLLVI 175 + D E R + + A +V+ GG L+I Sbjct: 257 CLHYF-----DAREAREVIGHAAGLVKPGGALLI 285 >3M70-A nrPDB Length = 286 Score = 34.4 bits (77), Expect = 0.068, Method: Composition-based stats. Identities = 13/41 (31%), Positives = 24/41 (58%) Query: 60 RVLDVACGTGVDSIMLVEEGFSVTSVDASDKMLKYALKERW 100 +VLD+ CG G +S+ L G+ VTS D ++ + + + + Sbjct: 123 KVLDLGCGQGRNSLYLSLLGYDVTSWDHNENSIAFLNETKE 163 >3G5T-A nrPDB Length = 299 Score = 34.0 bits (76), Expect = 0.071, Method: Composition-based stats. Identities = 24/122 (19%), Positives = 44/122 (36%), Gaps = 17/122 (13%) Query: 59 QRVLDVACGTGVDSIMLVEE---GFSVTSVDASDKMLKYALKERWNRRH-EPAFDKWVIE 114 + ++DV CG G ++ + +E + D S M+K A + + Sbjct: 38 KLLVDVGCGPGTATLQMAQELKPFEQIIGSDLSATMIKTAEVIKEGSPDTYKNVSFKISS 97 Query: 115 EANWMTLDKD-VPQSAEGGFDAVICLGNSFAHLPDCKGDQSEHRLALKNIASMVRAGGLL 173 ++ L D V + AV C AH D + Q ++ + +R G + Sbjct: 98 SDDFKFLGADSVDKQKIDMITAVEC-----AHWFDFEKFQ-------RSAYANLRKDGTI 145 Query: 174 VI 175 I Sbjct: 146 AI 147 >4YMH-A nrPDB Length = 240 Score = 34.0 bits (76), Expect = 0.076, Method: Composition-based stats. Identities = 14/88 (15%), Positives = 37/88 (42%), Gaps = 5/88 (5%) Query: 15 AEGLPDQYADGEAARVWQLYIGDTRSRTAEYKAWLLGLLRQHGCQRVLDVACGTGVDSIM 74 + G+PD + + D + + +W++ R +R+L++ C +G ++ Sbjct: 24 SHGIPDALVEHWEWTRTRFPDAD-KMSSRLQGSWMIFTARDRKPKRILEIGCYSGYSALA 82 Query: 75 LVE----EGFSVTSVDASDKMLKYALKE 98 E + +++ S KM+ + + Sbjct: 83 WYEGTRDTKAEIVTLEYSPKMIAASREA 110 >1WXW-A nrPDB Length = 382 Score = 34.0 bits (76), Expect = 0.081, Method: Composition-based stats. Identities = 28/120 (23%), Positives = 45/120 (37%), Gaps = 12/120 (10%) Query: 58 CQRVLDVACGTGVDSIMLVEEGFSVTSVDASDKMLKYALKERWNRRHEPAFDKWVIEEAN 117 +R LDV G ++ L V +VD+S + AL+ + EAN Sbjct: 210 GERALDVFSYAGGFALHLALGFREVVAVDSSAE----ALRRAEENARLNGLGNVRVLEAN 265 Query: 118 WMTLDKDVPQSAEGGFDAVICLGNSFAHLPDCKGDQSEHRLALKN----IASMVRAGGLL 173 L + + + FD V+ +FA K D A K +++ GG+L Sbjct: 266 AFDLLRRL-EKEGERFDLVVLDPPAFA---KGKKDVERAYRAYKEVNLRAIKLLKEGGIL 321 >3JWI-A nrPDB Length = 207 Score = 34.0 bits (76), Expect = 0.082, Method: Composition-based stats. Identities = 24/106 (22%), Positives = 50/106 (47%), Gaps = 9/106 (8%) Query: 48 WLLGLLRQHGCQRVLDVACGTG-VDSIMLVEEGFS-VTSVDASDKMLKYALKERWNRR-H 104 ++ +L+ ++V+D+ CG G + S++L ++ F +T VD S +L+ A R Sbjct: 18 TVVAVLKSVNAKKVIDLGCGEGNLLSLLLKDKSFEQITGVDVSYSVLERAKDRLKIDRLP 77 Query: 105 EPAFDKWVIEEANWMTLDKDVPQSAEGGFDAVICLGNSFAHLPDCK 150 E + + +++ + DK G+DA + HL + + Sbjct: 78 EMQRKRISLFQSSLVYRDKRF-----SGYDAATVI-EVIEHLDENR 117 >6BQC-A nrPDB Length = 383 Score = 34.0 bits (76), Expect = 0.083, Method: Composition-based stats. Identities = 35/183 (19%), Positives = 64/183 (34%), Gaps = 35/183 (19%) Query: 31 WQLYIGDTRSRTAEYKAWLLGLLRQHGCQRVLDVACG-TGVDSIMLVEEGFSVTSVDASD 89 W+ ++ A+ K + L+ RVLD+ CG G+ M SV V S Sbjct: 143 WKDADNLESAQQAKLK-MICEKLQLKPGMRVLDIGCGWGGLAHYMASNYDVSVVGVTISA 201 Query: 90 KMLKYALKERWNRRHEPAFDKWVIEEANWMTLDKDVPQSAEGGFDAVICLGNSFAHLPDC 149 + K A + D ++ + ++ L+ FD ++ +G F H+ Sbjct: 202 EQQKMAQERCE------GLDVTILLQ-DYRDLN--------DQFDRIVSVG-MFEHVGPK 245 Query: 150 KGDQSEHRLALKNIASMVRAGGLLVI-------DHRNYD-----HILSTGCAPPGKNIYY 197 D + ++ G+ ++ N D +I GC P + I Sbjct: 246 NYDT-----YFAVVDRNLKPEGIFLLHTIGSKKTDLNVDPWINKYIFPNGCLPSVRQIAQ 300 Query: 198 KSD 200 S+ Sbjct: 301 SSE 303 >4RYL-A nrPDB Length = 340 Score = 34.0 bits (76), Expect = 0.083, Method: Composition-based stats. Identities = 20/72 (27%), Positives = 32/72 (44%), Gaps = 2/72 (2%) Query: 39 RSRTAEYKAWLLGLLRQHGCQRVLDVACGTGVDSIMLVEEGF-SVTSVDASDKMLKYALK 97 + RT Y+ ++ + VLDV CGTG+ S+ + G V VD S ++L A+ Sbjct: 46 KIRTESYRDFIYQNPHIFKDKVVLDVGCGTGILSMFAAKAGAKKVLGVDQS-EILYQAMD 104 Query: 98 ERWNRRHEPAFD 109 + E Sbjct: 105 IIRLNKLEDTIT 116 >1N2X-A nrPDB Length = 301 Score = 34.0 bits (76), Expect = 0.086, Method: Composition-based stats. Identities = 15/88 (17%), Positives = 35/88 (39%), Gaps = 2/88 (2%) Query: 49 LLGLLRQHGCQRVLDVACGTGVDSIMLVEE--GFSVTSVDASDKMLKYALKERWNRRHEP 106 ++ L+ + +LD G G S ++E G + +D ++L+ A ++ Sbjct: 18 VIEFLKPEDEKIILDCTVGEGGHSRAILEHCPGCRIIGIDVDSEVLRIAEEKLKEFSDRV 77 Query: 107 AFDKWVIEEANWMTLDKDVPQSAEGGFD 134 + K EA+++ + + D Sbjct: 78 SLFKVSYREADFLLKTLGIEKVDGILMD 105 >5EGS-A nrPDB Length = 376 Score = 33.6 bits (75), Expect = 0.091, Method: Composition-based stats. Identities = 35/146 (23%), Positives = 56/146 (38%), Gaps = 21/146 (14%) Query: 32 QLYIGDTRSRTAEYKAWLLGLLRQHGCQRVLDVACGTGVDSIMLVEEGF-SVTSVDASDK 90 + I D R RT Y+ +L + VLDV GTG+ SI + G V +V+AS Sbjct: 59 EEMIAD-RVRTDAYRLGILRNWAALRGKTVLDVGAGTGILSIFCAQAGARRVYAVEAS-- 115 Query: 91 MLKYALKERWNRRHEPAFDKWVIEEANWMTLDKDVPQSAEGGFDAVIC--LGNSFAHLPD 148 + R R D+ + ++P+ DA++ +G H Sbjct: 116 --AIWQQAREVVRFNGLEDR--VHVLPGPVETVELPEQV----DAIVSEWMGYGLLH--- 164 Query: 149 CKGDQSEHRLALKNIASMVRAGGLLV 174 +S L ++ GGLL+ Sbjct: 165 ----ESMLSSVLHARTKWLKEGGLLL 186 >1L3B-A nrPDB Length = 192 Score = 33.6 bits (75), Expect = 0.10, Method: Composition-based stats. Identities = 29/135 (21%), Positives = 51/135 (37%), Gaps = 20/135 (14%) Query: 42 TAEYKAWLLGLLRQHGCQRVL-DVACGTGVDSIMLVEEGFSVTSVDASDKMLKYALKERW 100 TA L+ L + G V DV CGTG ++ L V ++D + + + E Sbjct: 17 TAMEVRCLIMCLAEPGKNDVAVDVGCGTGGVTLELAGRVRRVYAIDRNPE--AISTTEMN 74 Query: 101 NRRHEPAFDKWVIEEANWMTLDKDVPQSAEGGFDAVICLGNSFAHLPDCKGDQSEHRLAL 160 +RH N ++ D P++ D I + G E + L Sbjct: 75 LQRHGLG--------DNVTLMEGDAPEALCKIPDIDIAVVG---------GSGGELQEIL 117 Query: 161 KNIASMVRAGGLLVI 175 + I ++ GG +++ Sbjct: 118 RIIKDKLKPGGRIIV 132 >5W7M-A nrPDB Length = 312 Score = 33.6 bits (75), Expect = 0.11, Method: Composition-based stats. Identities = 34/171 (19%), Positives = 66/171 (38%), Gaps = 37/171 (21%) Query: 14 AAEGLPDQYADGEAARVWQLYIGDTRSRTAEYKAWLLGLLRQHGCQRVLDVACGTGVDSI 73 A +G+ D Y A ++ + Y D + ++ L L+ +LD+ACGTGV S Sbjct: 36 AGKGILDTYM--VAEKITRYYTQDLIQLSGLSESSLTPLV-------ILDLACGTGVVSD 86 Query: 74 MLVEE-------GFSVTSVDASDKMLKYALKERWNRRHEPAFDKWVIEEANWMTLDKDVP 126 L + + +T D S ++ + ++ R E + K V + + ++P Sbjct: 87 ALHDMLNFQPKGNWELTCGDISTELTGHVKQKILERGWENSIAKVVDAQ------NTELP 140 Query: 127 QSAEGGFDAVICLGNSFAHLPDCKG--DQSEHRLALKNIASMVRAGGLLVI 175 + H+ + A+K + +++ GG L I Sbjct: 141 -------------TGHYTHVFAALAFTSFPDTYAAMKEVMRILQPGGTLTI 178 >5X7F-A nrPDB Length = 235 Score = 33.6 bits (75), Expect = 0.11, Method: Composition-based stats. Identities = 37/175 (21%), Positives = 66/175 (37%), Gaps = 21/175 (12%) Query: 7 RTRSLGVAAEGLPDQYADGEAARVWQLYIGDTRSRTAEYKAWLLGLLRQHGCQRVLDVAC 66 R SL AEG + AR IG + T A L L + G + V +V Sbjct: 29 RGESLWAHAEGSISEDVILAGARERATDIG-AGAVTPAVGALLCLLAKLSGGKAVAEVGT 87 Query: 67 GTGVDSIMLVEEGFS---VTSVDASDKMLKYALKERWNRRHEPAFDKWVIEEANWMTLDK 123 G GV + L+ +T++D + L+ A + P+ + + A + Sbjct: 88 GAGVSGLWLLSGMRDDGVLTTIDIEPEHLRLARQAFAEAGIGPSRTRLISGRAQEV---- 143 Query: 124 DVPQSAEGGFDAVICLGNSFAHLPDCKGDQSEHRLALKNIASMVRAGGLLVIDHR 178 + + A+ +D V D + + ++R+GG++V+ HR Sbjct: 144 -LTRLADASYDLVFI-----------DADPIDQPDYVAEGVRLLRSGGVIVV-HR 185 >1G6Q-1 nrPDB Length = 328 Score = 33.2 bits (74), Expect = 0.12, Method: Composition-based stats. Identities = 19/58 (32%), Positives = 28/58 (48%), Gaps = 2/58 (3%) Query: 32 QLYIGDTRSRTAEYKAWLLGLLRQHGCQRVLDVACGTGVDSIMLVEEGFS-VTSVDAS 88 + + DT RT Y+ ++ + VLDV CGTG+ S+ + G V VD S Sbjct: 14 EEMLQDT-VRTLSYRNAIIQNKDLFKDKIVLDVGCGTGILSMFAAKHGAKHVIGVDMS 70 >6CU3-A nrPDB Length = 336 Score = 33.2 bits (74), Expect = 0.12, Method: Composition-based stats. Identities = 33/138 (23%), Positives = 48/138 (34%), Gaps = 12/138 (8%) Query: 41 RTAEYKAWLLGLLRQHGCQRVLDVACGTGVDSIMLVEEGFS-VTSVDASDKMLKYALKER 99 RT YK +L + VLD+ CGTG+ + + G V +D SD + K Sbjct: 35 RTNAYKNAILQNKHLFKDKVVLDIGCGTGILCLFAAKAGAKRVIGIDMSDIIDKARQIVS 94 Query: 100 WNRRHEPAFDKWVIEEANWMTLDKDVPQSAEGGFDAVICLGNSFAHLPDCKGDQSEHRLA 159 N VIE +D+ Q G I + + +S + Sbjct: 95 DNGYSH------VIELIKGKV--EDIAQLPFGIEKVDIIISEWMGYFLLY---ESMLQTV 143 Query: 160 LKNIASMVRAGGLLVIDH 177 L +R GG L D Sbjct: 144 LSARDRWLRPGGYLFPDK 161 >1X1B-A nrPDB Length = 359 Score = 33.2 bits (74), Expect = 0.13, Method: Composition-based stats. Identities = 28/154 (18%), Positives = 53/154 (34%), Gaps = 26/154 (16%) Query: 50 LGLLRQH----GCQRVLDVACGTGVDSIMLVEEGFSVTSVDASDKMLKYALKERWNRRHE 105 + LL + G ++++DV G G S +++ + S + L A+ E Sbjct: 179 IQLLLEEAKLDGVKKMIDVGGGIGDISAAMLKHFPELDSTILN---LPGAIDLVNENAAE 235 Query: 106 PAFDKWVIEEANWMTLDKDVPQSAEGGFDAVICLGNSFAHLPDCKGDQSEHRLALKNIAS 165 + D+ + + DAV L + + + + A + Sbjct: 236 KGV------ADRMRGIAVDIYKESYPEADAV--LFCRILYSANEQLSTIMCKKAFDAM-- 285 Query: 166 MVRAGGLLVIDHRNYDHILSTGCAPPGKNIYYKS 199 R+GG L+I D ++ P N Y S Sbjct: 286 --RSGGRLLI----LDMVIDD---PENPNFDYLS 310 >3I9F-A nrPDB Length = 170 Score = 33.2 bits (74), Expect = 0.14, Method: Composition-based stats. Identities = 33/146 (22%), Positives = 58/146 (39%), Gaps = 29/146 (19%) Query: 46 KAWLLGLLRQHGCQRVLDVACGTGVDSIMLVEEGFSVTSVDASDKMLKYALKERWNRRHE 105 + +L + ++D CG G L+E + +D + ALKE + Sbjct: 7 EEYLPNIFEGKKG-VIVDYGCGNGFYCKYLLEFATKLYCIDIN----VIALKEV-----K 56 Query: 106 PAFDKWVIEEANWMTLDKDVPQSAEGGFDAVICLGNSFAHLPDCKGDQSEHRLALKNIAS 165 FD + ++ K++P ++ I NSF + D + SE + LK+ Sbjct: 57 EKFDSVIT-----LSDPKEIPDNSVD----FILFANSFHDMDDKQHVISEVKRILKD--- 104 Query: 166 MVRAGGLLVIDHRNYDHILSTGCAPP 191 G +++ID R + TG PP Sbjct: 105 ---DGRVIIIDWRKEN----TGIGPP 123 >5LV5-A nrPDB Length = 403 Score = 33.2 bits (74), Expect = 0.14, Method: Composition-based stats. Identities = 34/146 (23%), Positives = 56/146 (38%), Gaps = 21/146 (14%) Query: 32 QLYIGDTRSRTAEYKAWLLGLLRQHGCQRVLDVACGTGVDSIMLVEEGF-SVTSVDASDK 90 + I D + RT Y+ +L + VLDV GTG+ SI + G V +V+AS Sbjct: 86 EEMIAD-QVRTEAYRLGILKNWAALRGKTVLDVGAGTGILSIFCAQAGARRVYAVEAS-- 142 Query: 91 MLKYALKERWNRRHEPAFDKWVIEEANWMTLDKDVPQSAEGGFDAVIC--LGNSFAHLPD 148 + R R D+ + ++P+ DA++ +G H Sbjct: 143 --AIWQQAREVVRLNGLEDR--VHVLPGPVETVELPERV----DAIVSEWMGYGLLH--- 191 Query: 149 CKGDQSEHRLALKNIASMVRAGGLLV 174 +S L ++ GGLL+ Sbjct: 192 ----ESMLSSVLHARTKWLKEGGLLL 213 >3BKX-A nrPDB Length = 275 Score = 33.2 bits (74), Expect = 0.14, Method: Composition-based stats. Identities = 37/159 (23%), Positives = 60/159 (37%), Gaps = 16/159 (10%) Query: 16 EGLPDQYADGEAARVWQLYIGDTRSRTAEYKAWLLGLLRQHGCQRVLDVACGTGVDSIML 75 + + D A G A + T R A +AW + +++L++ CG G S +L Sbjct: 7 DYITDLMALGPTANARTIQRRQTAHRLAIAEAWQV-----KPGEKILEIGCGQGDLSAVL 61 Query: 76 VEEGFS---VTSVD-ASDKMLK-YALKERWNRRHEPAFDKWVIEEANWMTLDKDVPQSAE 130 ++ S VT +D AS L + WN + N D D+ A+ Sbjct: 62 ADQVGSSGHVTGIDIASPDYGAPLTLGQAWNHLLAGPLGDRLTVHFNTNLSD-DLGPIAD 120 Query: 131 GGFDAVICLGNSFAHLPDCKGDQSEHRLALKNIASMVRA 169 FD V+ AH + L KN+A++ Sbjct: 121 QHFDRVV-----LAHSLWYFASANALALLFKNMAAVCDH 154 >1KP9-A nrPDB Length = 287 Score = 32.9 bits (73), Expect = 0.19, Method: Composition-based stats. Identities = 25/127 (19%), Positives = 46/127 (36%), Gaps = 18/127 (14%) Query: 50 LGLLRQHGCQRVLDVACGTGVDSIMLVEEG-FSVTSVDASDKMLKYALKERWNRRHEPAF 108 LG L +LDV CG G + VE+ +V + S + + N + Sbjct: 57 LGKLGLQPGMTLLDVGCGWGATMMRAVEKYDVNVVGLTLSKNQANHVQQLVANSEN---L 113 Query: 109 DKWVIEEANWMTLDKDVPQSAEGGFDAVICLGNSFAHLPDCKGDQSEHRLALKNIASMVR 168 + A W D+ V D ++ +G +F H + D ++ Sbjct: 114 RSKRVLLAGWEQFDEPV--------DRIVSIG-AFEHFGHERYDA-----FFSLAHRLLP 159 Query: 169 AGGLLVI 175 A G++++ Sbjct: 160 ADGVMLL 166 >1F3L-A nrPDB Length = 321 Score = 32.9 bits (73), Expect = 0.20, Method: Composition-based stats. Identities = 20/68 (29%), Positives = 33/68 (48%), Gaps = 2/68 (2%) Query: 39 RSRTAEYKAWLLGLLRQHGCQRVLDVACGTGVDSIMLVEEGF-SVTSVDASDKMLKYALK 97 + RT Y+ ++ + VLDV CGTG+ S+ + G V +VD S ++L A+ Sbjct: 27 KVRTESYRDFIYQNPHIFKDKVVLDVGCGTGILSMFAAKAGAKKVIAVDQS-EILYQAMD 85 Query: 98 ERWNRRHE 105 + E Sbjct: 86 IIRLNKLE 93 >5BP7-A nrPDB Length = 271 Score = 32.5 bits (72), Expect = 0.21, Method: Composition-based stats. Identities = 23/130 (17%), Positives = 39/130 (30%), Gaps = 18/130 (13%) Query: 47 AWLLGLLRQHGCQRVLDVACGTGVDSIMLV-EEGFSVTSVDASDKMLKYALKERWNRRHE 105 L LR RVLD+ G+G + G T +D S A Sbjct: 49 TTLGAALRLEPGTRVLDLGSGSGEMLCTWARDHGIIGTGIDMSQLFTAQAKLRAEELGVA 108 Query: 106 PAFDKWVIEEANWMTLDKDVPQSAEGGFDAVICLGNSFAHLPDCKGDQSEHRLALKNIAS 165 + + +++ DK A + + E +A Sbjct: 109 DRVTFIHGDASGYVSDDK-----------AGVAACVGATWIGGGVAGTIEL------LAR 151 Query: 166 MVRAGGLLVI 175 +R GG+++I Sbjct: 152 SLRPGGIILI 161 >2XVM-A nrPDB Length = 199 Score = 32.1 bits (71), Expect = 0.27, Method: Composition-based stats. Identities = 14/57 (24%), Positives = 23/57 (40%), Gaps = 5/57 (8%) Query: 35 IGDTRSRTAEYKAWLLGLLRQHGCQ-----RVLDVACGTGVDSIMLVEEGFSVTSVD 86 I D T +Y+ + + LD+ CG G +S+ L G+ V + D Sbjct: 5 IRDENYFTDKYELTRTHSEVLEAVKVVKPGKTLDLGCGNGRNSLYLAANGYDVDAWD 61 >4HG2-A nrPDB Length = 257 Score = 32.1 bits (71), Expect = 0.28, Method: Composition-based stats. Identities = 21/103 (20%), Positives = 35/103 (33%), Gaps = 17/103 (16%) Query: 62 LDVACGTGVDSIMLVEEGFSVTSVDASDKMLKYALKERWNRRHEPAFDKWVIEEANWMTL 121 LD CG+G S+ L E V +VD + ++ AL P V + Sbjct: 44 LDCGCGSGQASLGLAEFFERVHAVDPGEAQIRQAL-------RHPRVTYAVAPAEDTG-- 94 Query: 122 DKDVPQSAEGGFDAVICLGNSFAHLPDCKGDQSEHRLALKNIA 164 +P ++ + + H D +E R + A Sbjct: 95 ---LPPASVD-----VAIAAQAMHWFDLDRFWAELRRVARPGA 129 >5JMQ-A nrPDB Length = 446 Score = 32.1 bits (71), Expect = 0.29, Method: Composition-based stats. Identities = 20/72 (27%), Positives = 34/72 (47%), Gaps = 2/72 (2%) Query: 20 DQYADGEAARVWQLYIGDTRSRTAEYKAWLLGLLRQHGCQRVLDVACGTGVDSIMLVEEG 79 ++Y D L + + RT +Y + +L + +LDV CGTG+ S+ Sbjct: 113 EEYFDSYGTLKLHLEMLADQPRTTKYHSVILQNKESLKDKVILDVGCGTGIISLFCAHHA 172 Query: 80 --FSVTSVDASD 89 +V +V+ASD Sbjct: 173 RPKAVYAVEASD 184 >1Q2L-A nrPDB Length = 939 Score = 32.1 bits (71), Expect = 0.30, Method: Composition-based stats. Identities = 35/200 (17%), Positives = 65/200 (32%), Gaps = 39/200 (19%) Query: 16 EGLPDQYADGEAARVWQLYIGDTRSRTAEYKAWLLGLLRQHGCQRVLDVACGTGVDSIML 75 +G+ QY D A + + + +R +Y WL + + + LD Sbjct: 359 KGIDKQYFDELANVLDIDFRYPSITRDMDYVEWLADTMIRVPVEHTLD------------ 406 Query: 76 VEEGFSVTSVDASDKMLKYALKERWNRRHEPAFDKWVIEEANWMTLDKDVPQSAEGGFDA 135 +V+ +D+ A+K E W K+ DA Sbjct: 407 --------AVNIADRYDAKAVK-------ERLAMMTPQNARIWYISPKEPHNKTAYFVDA 451 Query: 136 VICLGNSFAHLP-DCKGDQSEHRLALKNIASMVRAGGLLVIDHRNYDH---ILSTG---- 187 + A D + ++ L+L + + L+ + YDH I+ Sbjct: 452 PYQVDKISAQTFADWQKKAADIALSLPELNPYIPDDFSLIKSEKKYDHPELIVDESNLRV 511 Query: 188 -CAPPGKNIYYKSDLTKDVT 206 AP + Y+ S+ DV+ Sbjct: 512 VYAP---SRYFASEPKADVS 528 >3DMF-A nrPDB Length = 381 Score = 32.1 bits (71), Expect = 0.31, Method: Composition-based stats. Identities = 28/124 (22%), Positives = 47/124 (37%), Gaps = 25/124 (20%) Query: 58 CQRVLDVACGTGVDSIMLVEEGFSVTSVD---ASDKMLKYALKERWNRRH--EPAFDKWV 112 ++VLD+ G G ++ L G V V+ AS L+ L+ + D+ + Sbjct: 234 GRQVLDLGAGYGALTLPLARMGAEVVGVEDDLASVLSLQKGLEANALKAQALHSDVDEAL 293 Query: 113 IEEANWMTLDKDVPQSAEGGFDAVICLGNSFAHLPDCKGDQSEHRLALKN-IASMVRAGG 171 EEA + + + P G AVI + A N A+ +R GG Sbjct: 294 TEEARFDIIVTNPPFHVGG---AVIL----------------DVAQAFVNVAAARLRPGG 334 Query: 172 LLVI 175 + + Sbjct: 335 VFFL 338 >3SVZ-A nrPDB Length = 263 Score = 32.1 bits (71), Expect = 0.33, Method: Composition-based stats. Identities = 8/36 (22%), Positives = 18/36 (50%), Gaps = 1/36 (2%) Query: 60 RVLDVACGTGVDSIMLVEEGF-SVTSVDASDKMLKY 94 ++ D+ CGTG ++ L + +T +D ++ Sbjct: 55 KIADIGCGTGGQTLFLADYVKGQITGIDLFPDFIEI 90 >6GKZ-A nrPDB Length = 351 Score = 31.7 bits (70), Expect = 0.40, Method: Composition-based stats. Identities = 22/120 (18%), Positives = 50/120 (41%), Gaps = 16/120 (13%) Query: 58 CQRVLDVACGTGVDSIMLVEEGFSVTSVDASDKMLKYALKERWNRRHEPAFDKWVIEEAN 117 Q VLD+ CG G ++ + ++ + ++ + + E +RR ++ A+ Sbjct: 124 GQSVLDLGCGQGALTLHVAQKYKNCRVTAVTNSVSQKEYIEEESRRRN--LLNVEVKLAD 181 Query: 118 WMTLDKDVPQSAEGGFDAVICLGNSFAHLPDCKGDQSEHRLALKNIASMVRAGGLLVIDH 177 T + +D ++ + F H+ + + L L+ I+ + GLL ++H Sbjct: 182 ITTHEM------AETYDRILVI-ELFEHMKNYE-------LLLRKISEWISKDGLLFLEH 227 >4AZW-A nrPDB Length = 471 Score = 31.3 bits (69), Expect = 0.48, Method: Composition-based stats. Identities = 21/104 (20%), Positives = 37/104 (35%), Gaps = 9/104 (8%) Query: 61 VLDVACGTGVDSIMLVEEGFSVTSVDASDKMLKYALKERWNRRHEPAFDKWVIEEANWMT 120 VLD+ C G S+ L +G ++ +D + + A E Sbjct: 70 VLDLGCAQGFFSLSLASKGATIVGIDFQQENINVCRALAEENPDFAA-------EFRVGR 122 Query: 121 LDKDVPQSAEGGFDAVICLGNSFAHLPDCKGDQSEHRLALKNIA 164 +++ + EG FD + +G S H E + L +A Sbjct: 123 IEEVIAALEEGEFD--LAIGLSVFHHIVHLHGIDEVKRLLSRLA 164 >4AZV-A nrPDB Length = 569 Score = 31.3 bits (69), Expect = 0.48, Method: Composition-based stats. Identities = 21/104 (20%), Positives = 37/104 (35%), Gaps = 9/104 (8%) Query: 61 VLDVACGTGVDSIMLVEEGFSVTSVDASDKMLKYALKERWNRRHEPAFDKWVIEEANWMT 120 VLD+ C G S+ L +G ++ +D + + A E Sbjct: 70 VLDLGCAQGFFSLSLASKGATIVGIDFQQENINVCRALAEENPDFAA-------EFRVGR 122 Query: 121 LDKDVPQSAEGGFDAVICLGNSFAHLPDCKGDQSEHRLALKNIA 164 +++ + EG FD + +G S H E + L +A Sbjct: 123 IEEVIAALEEGEFD--LAIGLSVFHHIVHLHGIDEVKRLLSRLA 164 >1P91-A nrPDB Length = 269 Score = 31.3 bits (69), Expect = 0.52, Method: Composition-based stats. Identities = 14/59 (23%), Positives = 24/59 (40%), Gaps = 5/59 (8%) Query: 44 EYKAWLLGLLRQH---GCQRVLDVACGTGVDSIMLVEEGFSVT--SVDASDKMLKYALK 97 + ++ LR+ VLD+ CG G + + +T +D S +K A K Sbjct: 69 PLRDAIVAQLRERLDDKATAVLDIGCGEGYYTHAFADALPEITTFGLDVSKVAIKAAAK 127 >2HNK-A nrPDB Length = 239 Score = 30.6 bits (67), Expect = 0.82, Method: Composition-based stats. Identities = 12/75 (16%), Positives = 26/75 (34%), Gaps = 4/75 (5%) Query: 38 TRSRTAEYKAWLLGLLRQ-HGCQRVLDVACGTGVDSIMLVEEGFS---VTSVDASDKMLK 93 + + + L +L + G +R++++ TG S+ + D S++ Sbjct: 40 ANMQISPEEGQFLNILTKISGAKRIIEIGTFTGYSSLCFASALPEDGKILCCDVSEEWTN 99 Query: 94 YALKERWNRRHEPAF 108 A K E Sbjct: 100 VARKYWKENGLENKI 114 >4QNV-A nrPDB Length = 323 Score = 30.6 bits (67), Expect = 0.83, Method: Composition-based stats. Identities = 14/57 (24%), Positives = 23/57 (40%), Gaps = 1/57 (1%) Query: 37 DTRSRTAEYKAWLLGLLRQHGCQRVLDVACGTGVDSIMLVEEGFS-VTSVDASDKML 92 DT R+ +L L + +LDV CG+G ++ G +D + L Sbjct: 102 DTEWRSDWKWDRVLPHLSDLTGRTILDVGCGSGYHMWRMIGAGAHLAVGIDPTQLFL 158 >4DCM-A nrPDB Length = 375 Score = 30.6 bits (67), Expect = 0.84, Method: Composition-based stats. Identities = 17/80 (21%), Positives = 32/80 (40%), Gaps = 9/80 (11%) Query: 61 VLDVACGTGVDSIMLVEEGFS--VTSVDASDKMLKYALKERWNRRHEPAFDKWVIEEANW 118 ++D+ CG GV + L+++ V VD S + + E A D+ Sbjct: 226 IVDLGCGNGVIGLTLLDKNPQAKVVFVDESPMAVASSRLNVETNMPE-ALDRC------E 278 Query: 119 MTLDKDVPQSAEGGFDAVIC 138 ++ + F+AV+C Sbjct: 279 FMINNALSGVEPFRFNAVLC 298 >5KPG-A nrPDB Length = 397 Score = 30.6 bits (67), Expect = 0.86, Method: Composition-based stats. Identities = 14/71 (19%), Positives = 31/71 (43%), Gaps = 6/71 (8%) Query: 34 YIGDTRSRTAEYKAWLLGLLRQHG----CQRVLDVACGTGVDSIMLVE--EGFSVTSVDA 87 Y D + E + +++ L + Q +LD+ CG G ++ + + G VT + Sbjct: 141 YFKDESTTLDESEVYMMDLYCERAQIKDGQSILDLGCGHGSLTLHVAQKYRGCKVTGITN 200 Query: 88 SDKMLKYALKE 98 S ++ + + Sbjct: 201 SVSQKEFIMDQ 211 >3CJR-A nrPDB Length = 254 Score = 30.6 bits (67), Expect = 0.88, Method: Composition-based stats. Identities = 14/53 (26%), Positives = 20/53 (37%) Query: 56 HGCQRVLDVACGTGVDSIMLVEEGFSVTSVDASDKMLKYALKERWNRRHEPAF 108 +VLD+ G+GV +I + G VD +L A P F Sbjct: 119 RPGDKVLDLGTGSGVLAIAAEKLGGKALGVDIDPMVLPQAEANAKRNGVRPRF 171 >3V8V-A nrPDB Length = 702 Score = 30.2 bits (66), Expect = 1.0, Method: Composition-based stats. Identities = 26/140 (18%), Positives = 54/140 (38%), Gaps = 11/140 (7%) Query: 58 CQRVLDVACGTGVDSIMLVEEGF-SVTSVDASDKMLKYALKERWNRRHEPAFDKWVIEEA 116 + L++ TG ++ G S T+VD S L++A + + + + Sbjct: 539 GKDFLNLFSYTGSATVHAGLGGARSTTTVDMSRTYLEWAERNLRLNGLTGRAHRLIQADC 598 Query: 117 NWMTLDKDVPQSAEGGFDAVICLGNSFAH---LPDCKGDQSEHRLALKNIASMVRAGGLL 173 + A FD + +F++ + D Q +H +K++ ++RAGG + Sbjct: 599 LAWLRE------ANEQFDLIFIDPPTFSNSKRMEDAFDVQRDHLALMKDLKRLLRAGGTI 652 Query: 174 VIDHRNYDHILS-TGCAPPG 192 + + + G A G Sbjct: 653 MFSNNKRGFRMDLDGLAKLG 672 >1VQ1-A nrPDB Length = 294 Score = 30.2 bits (66), Expect = 1.1, Method: Composition-based stats. Identities = 24/111 (21%), Positives = 48/111 (43%), Gaps = 9/111 (8%) Query: 15 AEGLPDQYADGE-----AARVWQLYIGDTRSRTAEYKAWLLGLLRQHGCQRVLDVACGTG 69 A G P Y GE + + + + R T E L L+R++G + V D+ G+G Sbjct: 86 ASGYPLHYILGEKEFMGLSFLVEEGVFVPRPETEELVELALELIRKYGIKTVADIGTGSG 145 Query: 70 VDSIMLVEEGFSVT-SVDASDKMLKYALKERWNRRHEPAFDKWVIEEANWM 119 + + + ++ + D S K ++ A K N D++ + + ++ Sbjct: 146 AIGVSVAKFSDAIVFATDVSSKAVEIARK---NAERHGVSDRFFVRKGEFL 193 >1PJZ-A nrPDB Length = 203 Score = 29.8 bits (65), Expect = 1.5, Method: Composition-based stats. Identities = 13/48 (27%), Positives = 20/48 (41%) Query: 57 GCQRVLDVACGTGVDSIMLVEEGFSVTSVDASDKMLKYALKERWNRRH 104 RVL CG D L +G+ V + S+ ++ ER + H Sbjct: 22 PGARVLVPLCGKSQDMSWLSGQGYHVVGAELSEAAVERYFTERGEQPH 69 >2YXL-A nrPDB Length = 450 Score = 29.8 bits (65), Expect = 1.6, Method: Composition-based stats. Identities = 29/142 (20%), Positives = 47/142 (33%), Gaps = 26/142 (18%) Query: 52 LLRQHGCQRVLDVACGTGVDSIMLVE--------EGFSVTSVDASDKMLKYALKERWNRR 103 +L + V+D+A G + L E F V DKM LK+ R Sbjct: 254 VLDPKPGETVVDLAAAPGGKTTHLAELMKNKGKIYAFDV------DKMRMKRLKDFVKRM 307 Query: 104 HEPAFDKWVIE-EANWMTLDKDVPQSAEGGFDAVICLGNSFAHLP--------DCKGDQS 154 V + + ++V DA + P D + S Sbjct: 308 GIKIVKPLVKDARKAPEIIGEEVADKVL--LDAPCTSSGTIGKNPELRWRLREDKINEMS 365 Query: 155 EH-RLALKNIASMVRAGGLLVI 175 + R L++ A +V+ GG L+ Sbjct: 366 QLQRELLESAARLVKPGGRLLY 387 >5E9J-A nrPDB Length = 274 Score = 29.8 bits (65), Expect = 1.6, Method: Composition-based stats. Identities = 29/142 (20%), Positives = 53/142 (37%), Gaps = 19/142 (13%) Query: 46 KAWLLGLLRQHGCQR------VLDVACGTGVDSIML----VEEGFSVTSVDASDKMLKYA 95 K+ L+G + Q+ VLD+ CG G D + + + D S K + Sbjct: 14 KSVLIGEFLEKVRQKKKRDITVLDLGCGKGGDLLKWKKGRINKLVCTDIADVSVKQCQQR 73 Query: 96 LKERWNRRHEPAF---DKWVIEEANWMTLDKDVPQSAEGGFDAVICLGNSFAHLPDCKGD 152 ++ NRR + + + + +DK + + FD IC H + Sbjct: 74 YEDMKNRRDSEYIFSAEFITADSSKELLIDK--FRDPQMCFD--ICSCQFVCHYSFESYE 129 Query: 153 QSEHRLALKNIASMVRAGGLLV 174 Q++ L+N + GG + Sbjct: 130 QADM--MLRNACERLSPGGYFI 149 >3BGV-A nrPDB Length = 313 Score = 29.8 bits (65), Expect = 1.6, Method: Composition-based stats. Identities = 29/142 (20%), Positives = 53/142 (37%), Gaps = 19/142 (13%) Query: 46 KAWLLGLLRQHGCQR------VLDVACGTGVDSIML----VEEGFSVTSVDASDKMLKYA 95 K+ L+G + Q+ VLD+ CG G D + + + D S K + Sbjct: 17 KSVLIGEFLEKVRQKKKRDITVLDLGCGKGGDLLKWKKGRINKLVCTDIADVSVKQCQQR 76 Query: 96 LKERWNRRHEPAF---DKWVIEEANWMTLDKDVPQSAEGGFDAVICLGNSFAHLPDCKGD 152 ++ NRR + + + + +DK + + FD IC H + Sbjct: 77 YEDMKNRRDSEYIFSAEFITADSSKELLIDK--FRDPQMCFD--ICSCQFVCHYSFESYE 132 Query: 153 QSEHRLALKNIASMVRAGGLLV 174 Q++ L+N + GG + Sbjct: 133 QADM--MLRNACERLSPGGYFI 152 >5FUB-A nrPDB Length = 337 Score = 29.8 bits (65), Expect = 1.7, Method: Composition-based stats. Identities = 26/104 (25%), Positives = 43/104 (41%), Gaps = 4/104 (3%) Query: 20 DQYADGEAARVWQLYIGDTRSRTAEYKAWLLGLLRQHGCQRVLDVACGTGVDSIM--LVE 77 D+Y L + + RT Y+ +L + VLD+ CGTGV S+ L+ Sbjct: 7 DEYFGNYGTLRLHLEMLSDKPRTETYRQVILSNSAALREKVVLDLGCGTGVISLFCALLA 66 Query: 78 EGFSVTSVDASDKMLKYALKERWNRRHEPAFDKWVIEEANWMTL 121 + V +V+AS M ++ + + E A +TL Sbjct: 67 KPAGVYAVEAS-SMAEHTEELVKQNGCDGVVT-VFQERAENLTL 108 >1NW6-A nrPDB Length = 319 Score = 29.4 bits (64), Expect = 1.8, Method: Composition-based stats. Identities = 15/57 (26%), Positives = 26/57 (45%) Query: 54 RQHGCQRVLDVACGTGVDSIMLVEEGFSVTSVDASDKMLKYALKERWNRRHEPAFDK 110 H VLD G+GV + + ++EG + DA+ +Y K+ + + DK Sbjct: 239 LSHPGSTVLDFFAGSGVTARVAIQEGRNSICTDAAPVFKEYYQKQLTFLQDDGLIDK 295 >5XN8-A nrPDB Length = 365 Score = 29.4 bits (64), Expect = 2.0, Method: Composition-based stats. Identities = 26/139 (18%), Positives = 46/139 (33%), Gaps = 17/139 (12%) Query: 49 LLGLLRQHGCQ--------RVLDVACGTGVDSIMLVEEGFSVTSVDASDKMLKYALKER- 99 L+ +L+QHGC+ + LD A G + V ++ S DA L E Sbjct: 76 LIAILKQHGCRGVVGVGGGKTLDTAKAIGYYQKLPVVVIPTIASTDAPTSALSVIYTEAG 135 Query: 100 --------WNRRHEPAFDKWVIEEANWMTLDKDVPQSAEGGFDAVICLGNSFAHLPDCKG 151 D +I +A L + + F+A C + + Sbjct: 136 EFEEYLIYPKNPDMVVMDTAIIAKAPVRLLVSGMGDALSTWFEAKACYDARATSMAGGQS 195 Query: 152 DQSEHRLALKNIASMVRAG 170 ++ LA +++ G Sbjct: 196 TEAALSLARLCYDTLLAEG 214 >1DUS-A nrPDB Length = 194 Score = 29.4 bits (64), Expect = 2.0, Method: Composition-based stats. Identities = 15/52 (28%), Positives = 24/52 (46%) Query: 61 VLDVACGTGVDSIMLVEEGFSVTSVDASDKMLKYALKERWNRRHEPAFDKWV 112 +LD+ CG GV I L +E S T D + + +K A + + + V Sbjct: 56 ILDLGCGYGVIGIALADEVKSTTMADINRRAIKLAKENIKLNNLDNYDIRVV 107 >1DL5-A nrPDB Length = 317 Score = 29.4 bits (64), Expect = 2.1, Method: Composition-based stats. Identities = 17/69 (24%), Positives = 33/69 (47%), Gaps = 6/69 (8%) Query: 36 GDTRSRTAEYKAWLLGLLRQHGCQRVLDVACGTGVDSIMLV----EEGFSVTSVDASDKM 91 T S+ + ++ + G RVL++ GTG ++ ++ E+G V SV+ S K+ Sbjct: 55 YSTSSQPSLMALFMEWVGLDKGM-RVLEIGGGTGYNAAVMSRVVGEKGL-VVSVEYSRKI 112 Query: 92 LKYALKERW 100 + A + Sbjct: 113 CEIAKRNVE 121 >3M6U-A nrPDB Length = 464 Score = 29.4 bits (64), Expect = 2.2, Method: Composition-based stats. Identities = 25/138 (18%), Positives = 45/138 (32%), Gaps = 20/138 (14%) Query: 52 LLRQHGCQRVLDVACGTGVDSIMLVEEGFSVTSVDASDKMLKYALKERWNRRHEPAFDKW 111 LL +RVLD+A G + L + +L + + R ++W Sbjct: 96 LLDPKPGERVLDLAAAPGGKTTHLAAR------MGGKGLLLANEVDGKRVRGLLENVERW 149 Query: 112 VIEEANWMTLDKDVPQSAEGGFDAVI----CLGNSF---------AHLPDCKGDQSEHRL 158 A + + ++ F V+ C G P +E + Sbjct: 150 GAPLAVTQAPPRALAEAFGTYFHRVLLDAPCSGEGMFRKDREAARHWGPSAPKRMAEVQK 209 Query: 159 A-LKNIASMVRAGGLLVI 175 A L + ++ GG+LV Sbjct: 210 ALLAQASRLLGPGGVLVY 227 >2H1R-A nrPDB Length = 299 Score = 29.0 bits (63), Expect = 2.4, Method: Composition-based stats. Identities = 11/37 (29%), Positives = 20/37 (54%) Query: 61 VLDVACGTGVDSIMLVEEGFSVTSVDASDKMLKYALK 97 VL++ CGTG ++ L+ V ++D +M+ K Sbjct: 46 VLEIGCGTGNLTVKLLPLAKKVITIDIDSRMISEVKK 82 >3NJR-A nrPDB Length = 204 Score = 29.0 bits (63), Expect = 2.5, Method: Composition-based stats. Identities = 16/99 (16%), Positives = 34/99 (34%), Gaps = 1/99 (1%) Query: 34 YIGDTRSRTAEYKAWLLGLLRQHGCQRVLDVACGTGVDSIMLVEEGFSVTSVDASDKMLK 93 + D + + +A L L + + D+ G+G S+ G +++ ++ Sbjct: 32 FAHDGQITKSPMRALTLAALAPRRGELLWDIGGGSGSVSVEWCLAGGRAITIEPRADRIE 91 Query: 94 YALKERWNRRHEPAFDKWVIEEANWMTLDKDVPQSAEGG 132 K P + V A D +P++ G Sbjct: 92 NIQKNIDTYGLSPR-MRAVQGTAPAALADLPLPEAVFIG 129 >2H11-A nrPDB Length = 232 Score = 29.0 bits (63), Expect = 2.6, Method: Composition-based stats. Identities = 21/112 (18%), Positives = 40/112 (35%), Gaps = 9/112 (8%) Query: 53 LRQHGCQRVLDVACGTGVDSIMLVEEGFSVTSVDASDKMLKYALKERWNRRHEPAFDKWV 112 L+ RV CG V+ + G SV V+ S+ ++ E+ E + Sbjct: 44 LKGKSGLRVFFPLCGKAVEMKWFADRGHSVVGVEISELGIQEFFTEQNLSYSEEPITEIP 103 Query: 113 IEE---------ANWMTLDKDVPQSAEGGFDAVICLGNSFAHLPDCKGDQSE 155 + + + D+P++ G FD + G A P + ++ Sbjct: 104 GTKVFKSSSGNISLYCCSIFDLPRTNIGKFDMIWDRGALVAINPGDRKCYAD 155 >2YVL-A nrPDB Length = 248 Score = 29.0 bits (63), Expect = 2.7, Method: Composition-based stats. Identities = 20/87 (22%), Positives = 35/87 (40%), Gaps = 8/87 (9%) Query: 41 RTAEYKAWLLGLLRQHGCQRVLDVACGTGVDSIMLVEEGFSVTSVDASDKMLKYALKERW 100 + + Y A L L ++ +RVL+ G+G +L E V + +A ++ K A K Sbjct: 78 KDSFYIALKLNLNKE---KRVLEFGTGSGALLAVLSEVAGEVWTFEAVEEFYKTAQKNLK 134 Query: 101 NRRHEPAFDKWVIEEANWMTLDKDVPQ 127 + N D +VP+ Sbjct: 135 KFNLGKNVKFF-----NVDFKDAEVPE 156 >3X0D-A nrPDB Length = 655 Score = 28.6 bits (62), Expect = 2.9, Method: Composition-based stats. Identities = 18/78 (23%), Positives = 27/78 (34%), Gaps = 6/78 (7%) Query: 61 VLDVACGTGVDSIMLVEEGFSVTSVDASDKMLKYALKERWNRRHEPAFDKWVIEEANWMT 120 VLD+ GTG+ S+M EG + L+ RH + W + Sbjct: 76 VLDIGTGTGLLSLMAAREGADKVTA------LEVFKPMGDCARHITSNSPWSDKITVISE 129 Query: 121 LDKDVPQSAEGGFDAVIC 138 DV Q D ++ Sbjct: 130 RSTDVSQIGGSRADIIVA 147 >1FP2-A nrPDB Length = 352 Score = 28.6 bits (62), Expect = 3.0, Method: Composition-based stats. Identities = 20/116 (17%), Positives = 39/116 (33%), Gaps = 13/116 (11%) Query: 56 HGCQRVLDVACGTGVDSIMLVEEGFSVTSVDASDKMLKYALKERWNRRHEPAFDKWVIEE 115 G + ++DV GTG + ++ E + + + L N + I Sbjct: 187 DGLESIVDVGGGTGTTAKIICETFPKLKCIVFDRPQVVENLSGSNNLTYVGGDMFTSIPN 246 Query: 116 ANWM--------TLDKDVPQSAEGGFDAVICLGN-----SFAHLPDCKGDQSEHRL 158 A+ + DKD + + +AV G + D K D+++ Sbjct: 247 ADAVLLKYILHNWTDKDCLRILKKCKEAVTNDGKRGKVTIIDMVIDKKKDENQVTQ 302 >6OGN-A nrPDB Length = 692 Score = 28.6 bits (62), Expect = 3.3, Method: Composition-based stats. Identities = 17/77 (22%), Positives = 29/77 (37%), Gaps = 3/77 (3%) Query: 53 LRQHGCQR-VLDVACGTGVDSIMLVEEGFSVT-SVDASDKMLKYALKERWNRRHEPAFDK 110 ++ G + VLD+ GTG+ S+M V G +++ M + A+K Sbjct: 59 VKDRGQKALVLDIGTGTGLLSMMAVTAGADFCYAIEVFKPMAEAAVKIVERNGFSDKIKV 118 Query: 111 WVIEEANWMT-LDKDVP 126 D D+P Sbjct: 119 INKHSTEVTVGPDGDLP 135 >1WF3-A nrPDB Length = 301 Score = 28.2 bits (61), Expect = 4.3, Method: Composition-based stats. Identities = 6/29 (20%), Positives = 12/29 (41%) Query: 33 LYIGDTRSRTAEYKAWLLGLLRQHGCQRV 61 Y D + W+ +LR+ +R+ Sbjct: 177 FYPEDYAKSDQTFGEWVAEILREEAMKRL 205 >2PWY-A nrPDB Length = 258 Score = 28.2 bits (61), Expect = 4.3, Method: Composition-based stats. Identities = 30/154 (19%), Positives = 55/154 (35%), Gaps = 16/154 (10%) Query: 32 QLYIGDTRSRTAEYK---AWLLGLLRQHGCQRVLDVACGTGVDSIMLVEEGFSVTSVD-- 86 + + RS T Y + ++ LL RVL+ G+G ++ L V+ Sbjct: 68 EYLLHMKRSATPTYPKDASAMVTLLDLAPGMRVLEAGTGSGGLTLFLARAVGEKGLVESY 127 Query: 87 -------ASDKMLKYALKERWNRR-HEPAFDKWVIEEANWMTLDKDVPQSAEGGFDAVIC 138 A + A + N R H ++ +EEA + + D+ + + A + Sbjct: 128 EARPHHLAQAERNVRAFWQVENVRFHLGKLEEAELEEAAYDGVALDLMEPWKVLEKAALA 187 Query: 139 LGNS---FAHLPDCKGDQSEHRLALKNIASMVRA 169 L A+LP+ R A + + R Sbjct: 188 LKPDRFLVAYLPNITQVLELVRAAEAHPFRLERV 221 >6IWT-A nrPDB Length = 364 Score = 28.2 bits (61), Expect = 4.6, Method: Composition-based stats. Identities = 10/65 (15%), Positives = 24/65 (36%) Query: 57 GCQRVLDVACGTGVDSIMLVEEGFSVTSVDASDKMLKYALKERWNRRHEPAFDKWVIEEA 116 G + V+DV GTG M++ + ++ ++ + H + E Sbjct: 201 GLKTVVDVGGGTGATLNMIISKYPNIKGINFDLPHVVEDAPSYPGVEHVGGDMFVSVPEG 260 Query: 117 NWMTL 121 + + + Sbjct: 261 DAIFM 265 >2QYO-A nrPDB Length = 357 Score = 28.2 bits (61), Expect = 4.7, Method: Composition-based stats. Identities = 12/72 (16%), Positives = 25/72 (34%) Query: 56 HGCQRVLDVACGTGVDSIMLVEEGFSVTSVDASDKMLKYALKERWNRRHEPAFDKWVIEE 115 G + ++DV G G ++ E +T V + L N + + + Sbjct: 192 EGLESIVDVGGGNGTTGKIICETFPKLTCVVFDRPKVVENLCGSNNLTYVGGDMFISVPK 251 Query: 116 ANWMTLDKDVPQ 127 A+ + L + Sbjct: 252 ADAVLLKAVLHD 263 >3BGI-A nrPDB Length = 260 Score = 27.9 bits (60), Expect = 5.0, Method: Composition-based stats. Identities = 26/138 (18%), Positives = 47/138 (34%), Gaps = 15/138 (10%) Query: 53 LRQHGCQRVLDVACGTGVDSIMLVEEGFSVTSVDAS---------DKMLKYALKERWNRR 103 L+ RV CG ++ + G +V V+ S ++ L Y + Sbjct: 72 LKGQSGLRVFFPLCGKAIEMKWFADRGHTVVGVEISEIGIREFFAEQNLSYTEEPLAEIA 131 Query: 104 HEPAFDKWVIEEANWMTLDKDVPQSAEGGFDAVICLGNSFAHLPDCKGDQSEHRLALKNI 163 F + + D+P++ G FD + G A P +H I Sbjct: 132 GAKVFKSSSGSISLYCCSIFDLPRANIGKFDRIWDRGALVAINP------GDHDRYADII 185 Query: 164 ASMVRAGGLLVIDHRNYD 181 S++R ++ +YD Sbjct: 186 LSLLRKEFQYLVAVLSYD 203 >5XOH-A nrPDB Length = 359 Score = 27.9 bits (60), Expect = 5.1, Method: Composition-based stats. Identities = 6/31 (19%), Positives = 17/31 (54%) Query: 56 HGCQRVLDVACGTGVDSIMLVEEGFSVTSVD 86 G + ++DV G+G M++ + ++ ++ Sbjct: 194 EGLKSIVDVGGGSGATLNMIISKYPTIKGIN 224 >1KYW-A nrPDB Length = 365 Score = 27.9 bits (60), Expect = 5.4, Method: Composition-based stats. Identities = 30/203 (14%), Positives = 64/203 (31%), Gaps = 41/203 (20%) Query: 56 HGCQRVLDVACGTGVDSIMLVEEGFSVTSVDASDKMLKYALKERWNRRHEPAFDKWVIEE 115 G + ++DV GTG +V + ++ ++ + H I + Sbjct: 199 EGLKSLVDVGGGTGAVINTIVSKYPTIKGINFDLPHVIEDAPSYPGVEHVGGDMFVSIPK 258 Query: 116 ANWMTLDKDVPQSAEGGFDAVICLGNSFAHLPDCKGDQSEHRLALKNIASMVRAGGLLVI 175 A+ + + ++ CL LKN + G +++ Sbjct: 259 ADAVFMKWICHDWSDEH-----CL------------------KFLKNCYEALPDNGKVIV 295 Query: 176 DHRNYDHILSTGCAPPGKNIYYKSDLTKDVTTSVLIVNNKAHMVTLDYTVQVPGAGQDGS 235 + IL P ++ K + DV +++ +N + G Sbjct: 296 ----AECILP---VAPDSSLATKGVVHIDV---IMLAHNPGGKERTQKEFEDLAKGA--- 342 Query: 236 PGLSKFRLSYYPHCLASFTELLQ 258 G F++ HC A T +++ Sbjct: 343 -GFQGFKV----HCNAFNTYIME 360 >4EVI-A nrPDB Length = 388 Score = 27.9 bits (60), Expect = 5.9, Method: Composition-based stats. Identities = 8/27 (29%), Positives = 14/27 (51%) Query: 56 HGCQRVLDVACGTGVDSIMLVEEGFSV 82 G ++DV GTG S ++ E ++ Sbjct: 219 EGLSSLVDVGGGTGNTSKVIAETFPNI 245 >2BGN-E nrPDB Length = 363 Score = 27.5 bits (59), Expect = 6.5, Method: Composition-based stats. Identities = 17/90 (18%), Positives = 33/90 (36%), Gaps = 4/90 (4%) Query: 132 GFDAVICLGNSFA----HLPDCKGDQSEHRLALKNIASMVRAGGLLVIDHRNYDHILSTG 187 G D + L + A ++P G + + M G++ ++ R H+L+ Sbjct: 51 GMDKPLTLPDFLAKFDYYMPAIAGCRDAIKRIAYEFVEMKAKDGVVYVEVRYSPHLLANS 110 Query: 188 CAPPGKNIYYKSDLTKDVTTSVLIVNNKAH 217 P + DLT D S++ + Sbjct: 111 KVEPIPWNQAEGDLTPDEVVSLVNQGLQEG 140 >3TTS-A nrPDB Length = 675 Score = 27.5 bits (59), Expect = 7.5, Method: Composition-based stats. Identities = 17/100 (17%), Positives = 28/100 (28%), Gaps = 2/100 (2%) Query: 30 VWQLYIGDTRSRTAEYKAWLLGLLRQHGCQRVLDVACGTGVDSIMLVEEGFSVTSVDASD 89 W D S + ++ L + L +A TG + ++ V VD Sbjct: 46 SWAKIQRDEVSYDFTWLDDIIERLTKENIY--LCLATSTGAHPAWMAKKYPDVLRVDYEG 103 Query: 90 KMLKYALKERWNRRHEPAFDKWVIEEANWMTLDKDVPQSA 129 + K+ + I KD PQ Sbjct: 104 RKRKFGGRHNSCPNSPTYRKYAKILAGKLAERYKDHPQIV 143 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.311 0.122 0.318 Lambda K H 0.267 0.0372 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 10,839,394 Number of Sequences: 36641 Number of extensions: 398142 Number of successful extensions: 1344 Number of sequences better than 10.0: 135 Number of HSP's better than 10.0 without gapping: 101 Number of HSP's successfully gapped in prelim test: 84 Number of HSP's that attempted gapping in prelim test: 1198 Number of HSP's gapped (non-prelim): 190 length of query: 295 length of database: 10,336,785 effective HSP length: 96 effective length of query: 199 effective length of database: 6,819,249 effective search space: 1357030551 effective search space used: 1357030551 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.4 bits) S2: 58 (27.1 bits)