BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q14117 (519 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 2VR2-A nrPDB 1078 0.0 4LCQ-A nrPDB 785 0.0 5YZA-A nrPDB 649 0.0 1KCX-A nrPDB 646 0.0 4CNT-A nrPDB 645 0.0 4CNS-A nrPDB 640 0.0 4B90-A nrPDB 615 e-176 2FTW-A nrPDB 614 e-176 5NKS-A nrPDB 613 e-176 4B91-A nrPDB 604 e-173 6AJD-A nrPDB 491 e-139 3DC8-A nrPDB 464 e-131 4TQT-A nrPDB 451 e-127 1YNY-A nrPDB 370 e-103 3SFW-A nrPDB 368 e-102 1K1D-A nrPDB 351 6e-97 1GKQ-A nrPDB 344 5e-95 1NFG-A nrPDB 291 5e-79 2FTY-A nrPDB 211 4e-55 1GKR-A nrPDB 171 6e-43 3E74-A nrPDB 133 2e-31 3HM7-A nrPDB 124 9e-29 3GRI-A nrPDB 105 6e-23 3MPG-A nrPDB 101 7e-22 2Z00-A nrPDB 73 3e-13 1XRT-A nrPDB 67 3e-11 2GWN-A nrPDB 54 2e-07 6HG1-A nrPDB 45 1e-04 2VUN-A nrPDB 41 0.001 1FWC-C nrPDB 40 0.002 4V1Y-A nrPDB 39 0.005 2VHL-A nrPDB 37 0.014 5T5I-A nrPDB 37 0.028 1RK6-A nrPDB 35 0.053 3MKV-A nrPDB 35 0.087 3OOQ-A nrPDB 35 0.098 2BB0-A nrPDB 34 0.13 2OOF-A nrPDB 34 0.17 3K7I-B nrPDB 34 0.18 6ASO-A nrPDB 33 0.22 6NBO-A nrPDB 33 0.33 2PUZ-A nrPDB 33 0.34 2Z1T-A nrPDB 33 0.34 2AQV-A nrPDB 33 0.36 3T8L-A nrPDB 33 0.37 3GIQ-A nrPDB 33 0.42 4CQD-A nrPDB 32 0.73 2P9B-A nrPDB 32 0.76 3HPA-A nrPDB 32 0.87 4CEX-C nrPDB 31 1.0 3MTW-A nrPDB 31 1.2 2OGJ-A nrPDB 30 2.1 2Y7H-A nrPDB 30 2.5 3IGH-X nrPDB 30 3.1 4LH8-A nrPDB 30 3.2 3N2C-A nrPDB 30 3.4 4Z42-C nrPDB 30 3.5 3GGM-A nrPDB 30 3.5 3QGK-C nrPDB 29 4.0 5YGQ-A nrPDB 29 4.5 1U83-A nrPDB 29 4.8 1YQC-A nrPDB 29 5.2 1AK1-A nrPDB 29 5.4 2PLM-A nrPDB 29 6.4 3ICJ-A nrPDB 28 7.4 2GBX-B nrPDB 28 8.3 2OOD-A nrPDB 28 8.9 >2VR2-A nrPDB Length = 541 Score = 1078 bits (2787), Expect = 0.0, Method: Compositional matrix adjust. Identities = 519/519 (100%), Positives = 519/519 (100%) Query: 1 MAAPSRLLIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVL 60 MAAPSRLLIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVL Sbjct: 23 MAAPSRLLIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVL 82 Query: 61 PGGIDTHTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSW 120 PGGIDTHTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSW Sbjct: 83 PGGIDTHTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSW 142 Query: 121 ADPKVCCDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEAFS 180 ADPKVCCDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEAFS Sbjct: 143 ADPKVCCDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEAFS 202 Query: 181 RCKEIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAV 240 RCKEIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAV Sbjct: 203 RCKEIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAV 262 Query: 241 NCPLYIVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMGPP 300 NCPLYIVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMGPP Sbjct: 263 NCPLYIVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMGPP 322 Query: 301 LRPDPSTPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIW 360 LRPDPSTPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIW Sbjct: 323 LRPDPSTPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIW 382 Query: 361 EKGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTHH 420 EKGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTHH Sbjct: 383 EKGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTHH 442 Query: 421 QAVNFNIFEGMVCHGVPLVTISRGKVVYEAGVFSVTAGDGKFIPRKPFAEYIYKRIKQRD 480 QAVNFNIFEGMVCHGVPLVTISRGKVVYEAGVFSVTAGDGKFIPRKPFAEYIYKRIKQRD Sbjct: 443 QAVNFNIFEGMVCHGVPLVTISRGKVVYEAGVFSVTAGDGKFIPRKPFAEYIYKRIKQRD 502 Query: 481 RTCTPTPVERAPYKGEVATLKSRVTKEDATAGTRKQAHP 519 RTCTPTPVERAPYKGEVATLKSRVTKEDATAGTRKQAHP Sbjct: 503 RTCTPTPVERAPYKGEVATLKSRVTKEDATAGTRKQAHP 541 >4LCQ-A nrPDB Length = 520 Score = 785 bits (2026), Expect = 0.0, Method: Compositional matrix adjust. Identities = 368/500 (73%), Positives = 428/500 (85%), Gaps = 4/500 (0%) Query: 1 MAAPSRLLIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVL 60 MA +LI+GG+VVN+D S +DV + G + +G DL P GA RV+DA +LV+ Sbjct: 21 MAEAGEILIKGGKVVNEDCSFFSDVHIRGGKIVEVGPDLRVPPGA----RVIDATDRLVI 76 Query: 61 PGGIDTHTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSW 120 PGGIDTHTHM+ FMG+R++DDFH GTKAAL+GGTTMI+DF + QKG SL+EA++ WR Sbjct: 77 PGGIDTHTHMELAFMGTRAVDDFHIGTKAALAGGTTMILDFVMTQKGQSLLEAYDLWRKT 136 Query: 121 ADPKVCCDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEAFS 180 ADPKVCCDYSLHVAVTWWSD+VK+EM+ L Q++GVNSFKMFMAYK L+M+ D ELY FS Sbjct: 137 ADPKVCCDYSLHVAVTWWSDEVKDEMRTLAQERGVNSFKMFMAYKGLFMLRDDELYAVFS 196 Query: 181 RCKEIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAV 240 CKE+GAIAQVHAENGDLIAEGAKKML+LGITGPEGHELCRPEAVEAEAT RAITIASAV Sbjct: 197 HCKEVGAIAQVHAENGDLIAEGAKKMLSLGITGPEGHELCRPEAVEAEATQRAITIASAV 256 Query: 241 NCPLYIVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMGPP 300 NCPLY+VHVMSKSAA V++ AR+DG+VV+GEPIAASLGTDGT+YW+K+W HAA +VMGPP Sbjct: 257 NCPLYVVHVMSKSAADVVSKARKDGRVVFGEPIAASLGTDGTNYWHKDWAHAAQYVMGPP 316 Query: 301 LRPDPSTPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIW 360 LRPDPSTP +LM+LLANDDLT TGTDNCTF+ CQKALGKDDFT+IPNGVNGVEDRMSVIW Sbjct: 317 LRPDPSTPGYLMDLLANDDLTLTGTDNCTFSRCQKALGKDDFTRIPNGVNGVEDRMSVIW 376 Query: 361 EKGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTHH 420 EKGVHSGKMDENRFVAVTS+NAAKIFN YP+KGRIA SDAD+VIWDPK TR ISA+THH Sbjct: 377 EKGVHSGKMDENRFVAVTSSNAAKIFNFYPQKGRIAKDSDADVVIWDPKTTRKISAQTHH 436 Query: 421 QAVNFNIFEGMVCHGVPLVTISRGKVVYEAGVFSVTAGDGKFIPRKPFAEYIYKRIKQRD 480 QAV++NIFEGM CHGVP+VT+SRG+VVYE G V+ G G+FI R+PF+E++YKRI+QRD Sbjct: 437 QAVDYNIFEGMECHGVPVVTVSRGRVVYEEGRLKVSPGQGRFIHRQPFSEFVYKRIRQRD 496 Query: 481 RTCTPTPVERAPYKGEVATL 500 P V R PY GEV L Sbjct: 497 EVGKPAVVIREPYAGEVVAL 516 >5YZA-A nrPDB Length = 525 Score = 649 bits (1674), Expect = 0.0, Method: Compositional matrix adjust. Identities = 308/514 (59%), Positives = 385/514 (74%), Gaps = 6/514 (1%) Query: 6 RLLIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGID 65 RLLI+GG++VNDD S AD+ +EDG+++ +G +L+ PGG ++ ++A ++V+PGGID Sbjct: 16 RLLIKGGKIVNDDQSFYADIYMEDGLIKQIGENLIVPGG----VKTIEAHSRMVIPGGID 71 Query: 66 THTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWADPKV 125 HT Q P G S DDF QGTKAAL+GGTTMIID +P+ G SL+ AF+ WR WAD K Sbjct: 72 VHTRFQMPDQGMTSADDFFQGTKAALAGGTTMIIDHVVPEPGTSLLAAFDQWREWADSKS 131 Query: 126 CCDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEAFSRCKEI 185 CCDYSLHV ++ W ++EEM+ LV+D GVNSF ++MA+KD + +TD ++YE S ++I Sbjct: 132 CCDYSLHVDISEWHKGIQEEMEALVKDHGVNSFLVYMAFKDRFQLTDCQIYEVLSVIRDI 191 Query: 186 GAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAVNCPLY 245 GAIAQVHAENGD+IAE +++L LGITGPEGH L RPE VEAEA RAITIA+ NCPLY Sbjct: 192 GAIAQVHAENGDIIAEEQQRILDLGITGPEGHVLSRPEEVEAEAVNRAITIANQTNCPLY 251 Query: 246 IVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMGPPLRPDP 305 I VMSKS+A+VIA AR+ G VVYGEPI ASLGTDG+HYW+K W AA V PPL PDP Sbjct: 252 ITKVMSKSSAEVIAQARKKGTVVYGEPITASLGTDGSHYWSKNWAKAAAFVTSPPLSPDP 311 Query: 306 STPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIWEKGVH 365 +TPDFL +LL+ DL TG+ +CTFNT QKA+GKD+FT IP G NG E+RMSVIW+K V Sbjct: 312 TTPDFLNSLLSCGDLQVTGSAHCTFNTAQKAVGKDNFTLIPEGTNGTEERMSVIWDKAVV 371 Query: 366 SGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTHHQAVNF 425 +GKMDEN+FVAVTSTNAAK+FNLYPRKGRIAVGSDAD+VIWDP +TISAKTH+ ++ + Sbjct: 372 TGKMDENQFVAVTSTNAAKVFNLYPRKGRIAVGSDADLVIWDPDSVKTISAKTHNSSLEY 431 Query: 426 NIFEGMVCHGVPLVTISRGKVVYEAGVFSVTAGDGKFIPRKPFAEYIYKRIKQRDRTCTP 485 NIFEGM C G PLV IS+GK+V E G VT G G++IPRKPF +++YKRIK R R Sbjct: 432 NIFEGMECRGSPLVVISQGKIVLEDGTLHVTEGSGRYIPRKPFPDFVYKRIKARSRLAEL 491 Query: 486 TPVERAPYKGEVATLKSRVTKEDATAGTRKQAHP 519 V R Y G V + VT + T + + P Sbjct: 492 RGVPRGLYDGPVCEVS--VTPKTVTPASSAKTDP 523 >1KCX-A nrPDB Length = 518 Score = 646 bits (1667), Expect = 0.0, Method: Compositional matrix adjust. Identities = 301/492 (61%), Positives = 383/492 (77%), Gaps = 4/492 (0%) Query: 6 RLLIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGID 65 RLLIRGGR++NDD S ADV +EDG+++ +G +L+ PGG ++ ++A G++V+PGGID Sbjct: 9 RLLIRGGRIINDDQSFYADVYLEDGLIKQIGENLIVPGG----VKTIEANGRMVIPGGID 64 Query: 66 THTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWADPKV 125 +T++Q P G S DDF QGTKAAL+GGTTMIID +P+ G SL+ +FE W AD K Sbjct: 65 VNTYLQKPSQGMTSADDFFQGTKAALAGGTTMIIDHVVPEPGSSLLTSFEKWHEAADTKS 124 Query: 126 CCDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEAFSRCKEI 185 CCDYSLHV +T W D V+EE+++LVQDKGVNSF+++MAYKDLY ++D +LYEAF+ K + Sbjct: 125 CCDYSLHVDITSWYDGVREELEVLVQDKGVNSFQVYMAYKDLYQMSDSQLYEAFTFLKGL 184 Query: 186 GAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAVNCPLY 245 GA+ VHAENGDLIA+ K++L +GITGPEGH L RPE +EAEA RAI IA +NCP+Y Sbjct: 185 GAVILVHAENGDLIAQEQKRILEMGITGPEGHALSRPEELEAEAVFRAIAIAGRINCPVY 244 Query: 246 IVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMGPPLRPDP 305 I VMSKSAA +IA AR+ G +V+GEPIAASLGTDGTHYW+K W AA V PPL PDP Sbjct: 245 ITKVMSKSAADIIALARKKGPLVFGEPIAASLGTDGTHYWSKNWAKAAAFVTSPPLSPDP 304 Query: 306 STPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIWEKGVH 365 +TPD+L +LLA DL TG+ +C ++T QKA+GKD+FT IP GVNG+E+RM+V+W+K V Sbjct: 305 TTPDYLTSLLACGDLQVTGSGHCPYSTAQKAVGKDNFTLIPEGVNGIEERMTVVWDKAVA 364 Query: 366 SGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTHHQAVNF 425 +GKMDEN+FVAVTSTNAAKIFNLYPRKGRIAVGSDAD+VIWDP +TI+AK+H V + Sbjct: 365 TGKMDENQFVAVTSTNAAKIFNLYPRKGRIAVGSDADVVIWDPDKMKTITAKSHKSTVEY 424 Query: 426 NIFEGMVCHGVPLVTISRGKVVYEAGVFSVTAGDGKFIPRKPFAEYIYKRIKQRDRTCTP 485 NIFEGM CHG PLV IS+GK+V+E G SV+ G G+FIPRKPF E++Y+R++ R + Sbjct: 425 NIFEGMECHGSPLVVISQGKIVFEDGNISVSKGMGRFIPRKPFPEHLYQRVRIRSKVFGL 484 Query: 486 TPVERAPYKGEV 497 V R Y G V Sbjct: 485 HSVSRGMYDGPV 496 >4CNT-A nrPDB Length = 570 Score = 645 bits (1665), Expect = 0.0, Method: Compositional matrix adjust. Identities = 300/497 (60%), Positives = 378/497 (76%), Gaps = 4/497 (0%) Query: 6 RLLIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGID 65 RLLI+GGR+VNDD S AD+ +EDG+++ +G +L+ PGG ++ ++A GK+V+PGGID Sbjct: 16 RLLIKGGRIVNDDQSFYADIYMEDGLIKQIGDNLIVPGG----VKTIEANGKMVIPGGID 71 Query: 66 THTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWADPKV 125 HTH Q P+ G ++DDF QGTKAAL+GGTTMIID +P+ SL EA+E WR WAD K Sbjct: 72 VHTHYQMPYKGMTTVDDFFQGTKAALAGGTTMIIDHVVPEPESSLTEAYEKWREWADGKS 131 Query: 126 CCDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEAFSRCKEI 185 CCDY+LHV +T W+D VK+E++ L++DKGVNSF ++MAYKDLY V++ ELYE F+ E+ Sbjct: 132 CCDYALHVDITHWNDSVKQEVQNLIKDKGVNSFMVYMAYKDLYQVSNTELYEIFTCLGEL 191 Query: 186 GAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAVNCPLY 245 GAIAQVHAENGD+IA+ +ML +GITGPEGH L RPE +EAEA RAITIAS NCPLY Sbjct: 192 GAIAQVHAENGDIIAQEQTRMLEMGITGPEGHVLSRPEELEAEAVFRAITIASQTNCPLY 251 Query: 246 IVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMGPPLRPDP 305 + VMSKSAA +I+ AR+ G VV+GEPI ASLG DGTHYW+K W AA V PPL PDP Sbjct: 252 VTKVMSKSAADLISQARKKGNVVFGEPITASLGIDGTHYWSKNWAKAAAFVTSPPLSPDP 311 Query: 306 STPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIWEKGVH 365 +TPD++ +LLA+ DL +G+ +CTF+T QKA+GKD+FT IP G NGVE+RMSVIW+K V Sbjct: 312 TTPDYINSLLASGDLQLSGSAHCTFSTAQKAIGKDNFTAIPEGTNGVEERMSVIWDKAVA 371 Query: 366 SGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTHHQAVNF 425 +GKMDEN+FVAVTSTNAAKIFNLYPRKGRI+VGSD+D+VIWDP + +SAK H A + Sbjct: 372 TGKMDENQFVAVTSTNAAKIFNLYPRKGRISVGSDSDLVIWDPDAVKIVSAKNHQSAAEY 431 Query: 426 NIFEGMVCHGVPLVTISRGKVVYEAGVFSVTAGDGKFIPRKPFAEYIYKRIKQRDRTCTP 485 NIFEGM G PLV I +GK++ E G VT G G+FIP PF++Y+YKRIK R + Sbjct: 432 NIFEGMELRGAPLVVICQGKIMLEDGNLHVTQGAGRFIPCSPFSDYVYKRIKARRKMADL 491 Query: 486 TPVERAPYKGEVATLKS 502 V R Y G V L + Sbjct: 492 HAVPRGMYDGPVFDLTT 508 >4CNS-A nrPDB Length = 480 Score = 640 bits (1652), Expect = 0.0, Method: Compositional matrix adjust. Identities = 294/476 (61%), Positives = 371/476 (77%), Gaps = 4/476 (0%) Query: 6 RLLIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGID 65 RLLI+GGR+VNDD S AD+ +EDG+++ +G +L+ PGG ++ ++A GK+V+PGGID Sbjct: 6 RLLIKGGRIVNDDQSFYADIYMEDGLIKQIGDNLIVPGG----VKTIEANGKMVIPGGID 61 Query: 66 THTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWADPKV 125 HTH Q P+ G ++DDF QGTKAAL+GGTTMIID +P+ SL EA+E WR WAD K Sbjct: 62 VHTHYQMPYKGMTTVDDFFQGTKAALAGGTTMIIDHVVPEPESSLTEAYEKWREWADGKS 121 Query: 126 CCDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEAFSRCKEI 185 CCDY+LHV +T W+D VK+E++ L++DKGVNSF ++MAYKDLY V++ ELYE F+ E+ Sbjct: 122 CCDYALHVDITHWNDSVKQEVQNLIKDKGVNSFMVYMAYKDLYQVSNTELYEIFTCLGEL 181 Query: 186 GAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAVNCPLY 245 GAIAQVHAENGD+IA+ +ML +GITGPEGH L RPE +EAEA RAITIAS NCPLY Sbjct: 182 GAIAQVHAENGDIIAQEQTRMLEMGITGPEGHVLSRPEELEAEAVFRAITIASQTNCPLY 241 Query: 246 IVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMGPPLRPDP 305 + VMSKSAA +I+ AR+ G VV+GEPI ASLG DGTHYW+K W AA V PPL PDP Sbjct: 242 VTKVMSKSAADLISQARKKGNVVFGEPITASLGIDGTHYWSKNWAKAAAFVTSPPLSPDP 301 Query: 306 STPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIWEKGVH 365 +TPD++ +LLA+ DL +G+ +CTF+T QKA+GKD+FT IP G NGVE+RMSVIW+K V Sbjct: 302 TTPDYINSLLASGDLQLSGSAHCTFSTAQKAIGKDNFTAIPEGTNGVEERMSVIWDKAVA 361 Query: 366 SGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTHHQAVNF 425 +GKMDEN+FVAVTSTNAAKIFNLYPRKGRI+VGSD+D+VIWDP + +SAK H A + Sbjct: 362 TGKMDENQFVAVTSTNAAKIFNLYPRKGRISVGSDSDLVIWDPDAVKIVSAKNHQSAAEY 421 Query: 426 NIFEGMVCHGVPLVTISRGKVVYEAGVFSVTAGDGKFIPRKPFAEYIYKRIKQRDR 481 NIFEGM G PLV I +GK++ E G VT G G+FIP PF++Y+YKRIK R + Sbjct: 422 NIFEGMELRGAPLVVICQGKIMLEDGNLHVTQGAGRFIPCSPFSDYVYKRIKARRK 477 >4B90-A nrPDB Length = 586 Score = 615 bits (1587), Expect = e-176, Method: Compositional matrix adjust. Identities = 297/509 (58%), Positives = 380/509 (74%), Gaps = 4/509 (0%) Query: 2 AAPSRLLIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLP 61 +A R+LI+GG+VVNDD + ADV +E+G+++ +G +L+ PGGA +V+DA GKLV+P Sbjct: 27 SASVRILIKGGKVVNDDCTHEADVYIENGIIQQVGRELMIPGGA----KVIDATGKLVIP 82 Query: 62 GGIDTHTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWA 121 GGIDT TH FM + +DDF+ GTKAAL GGTTMII +P K SL++A+E R A Sbjct: 83 GGIDTSTHFHQTFMNATCVDDFYHGTKAALVGGTTMIIGHVLPDKETSLVDAYEKCRGLA 142 Query: 122 DPKVCCDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEAFSR 181 DPKVCCDY+LHV +TWW+ +VK EM+ LV++KGVNSF+MFM YKDLYM+ D ELY+ Sbjct: 143 DPKVCCDYALHVGITWWAPKVKAEMETLVREKGVNSFQMFMTYKDLYMLRDSELYQVLHA 202 Query: 182 CKEIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAVN 241 CK+IGAIA+VHAENG+L+AEGAK+ L LGITGPEG E+ RPE +EAEAT R ITIA+ + Sbjct: 203 CKDIGAIARVHAENGELVAEGAKEALDLGITGPEGIEISRPEELEAEATHRVITIANRTH 262 Query: 242 CPLYIVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMGPPL 301 CP+Y+V+V S SA VIA A+ GKVV E A G HY++++W HAA +V PPL Sbjct: 263 CPIYLVNVSSISAGDVIAAAKMQGKVVLAETTTAHATLTGLHYYHQDWSHAAAYVTVPPL 322 Query: 302 RPDPSTPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIWE 361 R D +T +LM+LLAND L +D+ F T QKA+GK+DFTKIP+GV+GV+DRMSVIWE Sbjct: 323 RLDTNTSTYLMSLLANDTLNIVASDHRPFTTKQKAMGKEDFTKIPHGVSGVQDRMSVIWE 382 Query: 362 KGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTHHQ 421 +GV GKMDENRFVAVTS+NAAK+ NLYPRKGRI G+DAD+V+WDP+ T+TISA T Q Sbjct: 383 RGVVGGKMDENRFVAVTSSNAAKLLNLYPRKGRIIPGADADVVVWDPEATKTISASTQVQ 442 Query: 422 AVNFNIFEGMVCHGVPLVTISRGKVVYEAGVFSVTAGDGKFIPRKPFAEYIYKRIKQRDR 481 +FN++E M CHGVPLVTISRG+VVYE GVF G GKF P + F + +YK++ QR++ Sbjct: 443 GGDFNLYENMRCHGVPLVTISRGRVVYENGVFMCAEGTGKFCPLRSFPDTVYKKLVQREK 502 Query: 482 TCTPTPVERAPYKGEVATLKSRVTKEDAT 510 T V+R PY G+VA + KE T Sbjct: 503 TLKVRGVDRTPYLGDVAVVVHPGKKEMGT 531 >2FTW-A nrPDB Length = 521 Score = 614 bits (1584), Expect = e-176, Method: Compositional matrix adjust. Identities = 294/492 (59%), Positives = 366/492 (74%), Gaps = 7/492 (1%) Query: 7 LLIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGIDT 66 +LI+ G VVNDD +DVLVE+G+++ + ++ P G++V+DA KL+LPGGIDT Sbjct: 10 ILIKNGTVVNDDRYFKSDVLVENGIIKEISKNIEPK----EGIKVVDATDKLLLPGGIDT 65 Query: 67 HTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWADPKVC 126 HTH Q PFMG+ S+DDF GT+AA++GGTT IIDF IP +G SL+EA++ W+ WAD KV Sbjct: 66 HTHFQLPFMGTVSVDDFDIGTQAAVAGGTTFIIDFVIPTRGQSLLEAYDQWKKWADEKVN 125 Query: 127 CDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEAFSRCKEIG 186 CDYSLHVA+TWWS+QV EM+ILV+++GVNSFK FMAYK+ +MVTD E+Y F RCKE+G Sbjct: 126 CDYSLHVAITWWSEQVSREMEILVKERGVNSFKCFMAYKNSFMVTDQEMYHIFKRCKELG 185 Query: 187 AIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAVNCPLYI 246 AIAQVHAENGD++ EG KKML +GITGPEGHEL RPEA+EAEAT RAI IA +V P+YI Sbjct: 186 AIAQVHAENGDMVFEGQKKMLEMGITGPEGHELSRPEALEAEATNRAIVIADSVCTPVYI 245 Query: 247 VHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMGPPLRPDPS 306 VHV S AA VI R++G VYGEPIAA LG DG+H WN +W HAA VMGPP+RPDP Sbjct: 246 VHVQSIGAADVICKHRKEGVRVYGEPIAAGLGVDGSHMWNHDWRHAAAFVMGPPIRPDPR 305 Query: 307 TPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIWEKGVHS 366 T LM+ LA DL GTDNCTF QKA+GKDDFTKIPNGVNGVEDRMS++WE GV++ Sbjct: 306 TKGVLMDYLARGDLDCVGTDNCTFCADQKAMGKDDFTKIPNGVNGVEDRMSIVWENGVNT 365 Query: 367 GKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTHHQAVNFN 426 GK+ +FV TS+ A+IFN+YPRKGRI VG D DIVIWDP ++TIS THH AV+FN Sbjct: 366 GKLTWCQFVRATSSERARIFNIYPRKGRIDVGCDGDIVIWDPNQSKTISKDTHHHAVDFN 425 Query: 427 IFEGMVCHGVPLVTISRGKVVYEAGVFSVTAGDGKFIPRKPFAEYIYKRIKQRD--RTCT 484 IFEG+ G+ + TI G +V+ S G G+F+PR PF ++ I+QRD R Sbjct: 426 IFEGIKVTGIAVTTIVAGNIVWSDNKLSCVKGSGRFVPRPPFGP-VFDGIEQRDKVRNEL 484 Query: 485 PTPVERAPYKGE 496 V+R PY+ + Sbjct: 485 LRKVDRKPYEDD 496 >5NKS-A nrPDB Length = 573 Score = 613 bits (1581), Expect = e-176, Method: Compositional matrix adjust. Identities = 292/492 (59%), Positives = 362/492 (73%), Gaps = 4/492 (0%) Query: 6 RLLIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGID 65 RLLIRGGR+VNDD S ADV VEDG+++ +G +L+ PGG ++ +DA G +VLPGG+D Sbjct: 17 RLLIRGGRIVNDDQSFYADVHVEDGLIKQIGENLIVPGG----IKTIDAHGLMVLPGGVD 72 Query: 66 THTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWADPKV 125 HT +Q P +G DDF QGTKAAL+GGTTMI+D P G SL+ A+E WR AD Sbjct: 73 VHTRLQMPVLGMTPADDFCQGTKAALAGGTTMILDHVFPDTGVSLLAAYEQWRERADSAA 132 Query: 126 CCDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEAFSRCKEI 185 CCDYSLHV +T W + +KEE++ LV++KGVNSF +FMAYKD +D ++YE FS +++ Sbjct: 133 CCDYSLHVDITRWHESIKEELEALVKEKGVNSFLVFMAYKDRCQCSDSQMYEIFSIIRDL 192 Query: 186 GAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAVNCPLY 245 GA+AQVHAENGD++ E K++L LGITGPEGH L PE VEAEA RA+TIA NCPLY Sbjct: 193 GALAQVHAENGDIVEEEQKRLLELGITGPEGHVLSHPEEVEAEAVYRAVTIAKQANCPLY 252 Query: 246 IVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMGPPLRPDP 305 + VMSK AA IA A+R G VV+GEPI ASLGTDG+HYW+K W AA V PP+ PDP Sbjct: 253 VTKVMSKGAADAIAQAKRRGVVVFGEPITASLGTDGSHYWSKNWAKAAAFVTSPPVNPDP 312 Query: 306 STPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIWEKGVH 365 +T D L LL++ DL TG+ +CTF T QKA+GKD+F IP G NG+E+RMS++WEK V Sbjct: 313 TTADHLTCLLSSGDLQVTGSAHCTFTTAQKAVGKDNFALIPEGTNGIEERMSMVWEKCVA 372 Query: 366 SGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTHHQAVNF 425 SGKMDEN FVAVTSTNAAKIFN YPRKGR+AVGSDAD+VIW+PK T+ ISAKTH+ V + Sbjct: 373 SGKMDENEFVAVTSTNAAKIFNFYPRKGRVAVGSDADLVIWNPKATKIISAKTHNLNVEY 432 Query: 426 NIFEGMVCHGVPLVTISRGKVVYEAGVFSVTAGDGKFIPRKPFAEYIYKRIKQRDRTCTP 485 NIFEG+ C G P V IS+G+V E G VT G G+F+PRK F +++YKRIK R+R Sbjct: 433 NIFEGVECRGAPAVVISQGRVALEDGKMFVTPGAGRFVPRKTFPDFVYKRIKARNRLAEI 492 Query: 486 TPVERAPYKGEV 497 V R Y G V Sbjct: 493 HGVPRGLYDGPV 504 >4B91-A nrPDB Length = 484 Score = 604 bits (1557), Expect = e-173, Method: Compositional matrix adjust. Identities = 287/481 (59%), Positives = 367/481 (76%), Gaps = 4/481 (0%) Query: 2 AAPSRLLIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLP 61 +A R+LI+GG+VVNDD + ADV +E+G+++ +G +L+ PGGA +V+DA GKLV+P Sbjct: 6 SASVRILIKGGKVVNDDCTHEADVYIENGIIQQVGRELMIPGGA----KVIDATGKLVIP 61 Query: 62 GGIDTHTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWA 121 GGIDT TH FM + +DDF+ GTKAAL GGTTMII +P K SL++A+E R A Sbjct: 62 GGIDTSTHFHQTFMNATCVDDFYHGTKAALVGGTTMIIGHVLPDKETSLVDAYEKCRGLA 121 Query: 122 DPKVCCDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEAFSR 181 DPKVCCDY+LHV +TWW+ +VK EM+ LV++KGVNSF+MFM YKDLYM+ D ELY+ Sbjct: 122 DPKVCCDYALHVGITWWAPKVKAEMETLVREKGVNSFQMFMTYKDLYMLRDSELYQVLHA 181 Query: 182 CKEIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAVN 241 CK+IGAIA+VHAENG+L+AEGAK+ L LGITGPEG E+ RPE +EAEAT R ITIA+ + Sbjct: 182 CKDIGAIARVHAENGELVAEGAKEALDLGITGPEGIEISRPEELEAEATHRVITIANRTH 241 Query: 242 CPLYIVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMGPPL 301 CP+Y+V+V S SA VIA A+ GKVV E A G HY++++W HAA +V PPL Sbjct: 242 CPIYLVNVSSISAGDVIAAAKMQGKVVLAETTTAHATLTGLHYYHQDWSHAAAYVTVPPL 301 Query: 302 RPDPSTPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIWE 361 R D +T +LM+LLAND L +D+ F T QKA+GK+DFTKIP+GV+GV+DRMSVIWE Sbjct: 302 RLDTNTSTYLMSLLANDTLNIVASDHRPFTTKQKAMGKEDFTKIPHGVSGVQDRMSVIWE 361 Query: 362 KGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTHHQ 421 +GV GKMDENRFVAVTS+NAAK+ NLYPRKGRI G+DAD+V+WDP+ T+TISA T Q Sbjct: 362 RGVVGGKMDENRFVAVTSSNAAKLLNLYPRKGRIIPGADADVVVWDPEATKTISASTQVQ 421 Query: 422 AVNFNIFEGMVCHGVPLVTISRGKVVYEAGVFSVTAGDGKFIPRKPFAEYIYKRIKQRDR 481 +FN++E M CHGVPLVTISRG+VVYE GVF G GKF P + F + +YK++ QR++ Sbjct: 422 GGDFNLYENMRCHGVPLVTISRGRVVYENGVFMCAEGTGKFCPLRSFPDTVYKKLVQREK 481 Query: 482 T 482 T Sbjct: 482 T 482 >6AJD-A nrPDB Length = 485 Score = 491 bits (1264), Expect = e-139, Method: Compositional matrix adjust. Identities = 248/484 (51%), Positives = 322/484 (66%), Gaps = 7/484 (1%) Query: 7 LLIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGIDT 66 LLIRG VV + S ADVL +G+++A+G +L P+G VLD G+ ++PGGID Sbjct: 3 LLIRGATVVTHEESYRADVLCANGLIQAIGENL----ETPSGCDVLDGGGQYLMPGGIDP 58 Query: 67 HTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWADPKVC 126 HTHMQ PFMG+ + +DF GT A L+GGTT IIDF IP SL+EAF TWR WA K Sbjct: 59 HTHMQLPFMGTVASEDFFSGTAAGLAGGTTSIIDFVIPNPRQSLLEAFHTWRGWAQ-KSA 117 Query: 127 CDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEAFSRCKEIG 186 DY HVA+TWWSD+V EM LV GVNSFK FMAYK+ M D L +F RC E+G Sbjct: 118 ADYGFHVAITWWSDEVAREMGELVAQHGVNSFKHFMAYKNAIMAADDTLVASFERCLELG 177 Query: 187 AIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAVNCPLYI 246 A+ VHAENG+L+ +K+LA G+TGPE H L RP VE EA RAI IA + PLY+ Sbjct: 178 AVPTVHAENGELVFHLQQKLLAQGLTGPEAHPLSRPPQVEGEAASRAIRIAETLGTPLYL 237 Query: 247 VHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMGPPLRPDPS 306 VH+ S+ A IA AR G+ VYGE +A L D + Y + +W AA +VM PP RP Sbjct: 238 VHISSREALDEIAYARAKGQPVYGEVLAGHLLLDDSVYRHPDWATAAGYVMSPPFRPVEH 297 Query: 307 TPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIWEKGVHS 366 + L L + +L TT TD+C F QKA+G+DDF+KIPNG G+EDRM+++W+ GV+S Sbjct: 298 Q-EALWRGLQSGNLHTTATDHCCFCAEQKAMGRDDFSKIPNGTAGIEDRMALLWDAGVNS 356 Query: 367 GKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTHHQAVNFN 426 G++ + FVA+TSTN AKIFNL+PRKG I VG+DAD+V+WDP+G+RT+SA THHQ V+FN Sbjct: 357 GRLSMHEFVALTSTNTAKIFNLFPRKGAIRVGADADLVLWDPQGSRTLSAATHHQRVDFN 416 Query: 427 IFEGMVCHGVPLVTISRGKVVYEAGVFSVTAGDGKFIPRKPFAEYIYKRIKQRDRTCTPT 486 IFEG G+P TIS+GK+++ AG G G+++ R P +Y+ + +R P Sbjct: 417 IFEGRTVRGIPSHTISQGKLLWAAGDLRAEPGAGRYVER-PAYPSVYEVLGRRAERQRPV 475 Query: 487 PVER 490 VER Sbjct: 476 AVER 479 >3DC8-A nrPDB Length = 490 Score = 464 bits (1195), Expect = e-131, Method: Compositional matrix adjust. Identities = 227/461 (49%), Positives = 299/461 (64%), Gaps = 9/461 (1%) Query: 8 LIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGIDTH 67 +I+GG +V D + ADV VE G + +G +L +G LDA G V+PGGID H Sbjct: 4 VIKGGTIVTADLTYKADVKVEGGRIVEIGPNL-------SGAETLDATGCYVMPGGIDPH 56 Query: 68 THMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWADPKVCC 127 TH++ PFMG+ S DDF GT+AAL+GGTTM++DFA+P G SL+EA W + + C Sbjct: 57 THLEMPFMGTYSSDDFESGTRAALAGGTTMVVDFALPSPGQSLLEALTMWDN-KSTRANC 115 Query: 128 DYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEAFSRCKEIGA 187 DYS H+A+TWW +QV EM+ +V+DKG+N+FK FMAYK MV D E++ +F RC +GA Sbjct: 116 DYSFHMAITWWGEQVFNEMETIVKDKGINTFKHFMAYKGALMVDDDEMFSSFQRCAALGA 175 Query: 188 IAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAVNCPLYIV 247 + VHAENGD++A+ K+LA G +GPE H RP VE EA RAI IA CP+YIV Sbjct: 176 LPLVHAENGDVVAQLQAKLLAEGNSGPEAHAYSRPAEVEGEAANRAIMIADMAGCPVYIV 235 Query: 248 HVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMGPPLRPDPST 307 H + A + I AR G V+GEP+ L D T Y++K+W HAA VM PP R + Sbjct: 236 HTSCEQAHEAIRRARAKGMRVFGEPLIQHLTLDETEYFDKDWDHAARRVMSPPFR-NKLH 294 Query: 308 PDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIWEKGVHSG 367 D L LA+ L TD+C F T QK G DFT+IPNG G+EDRM ++W GV +G Sbjct: 295 QDSLWAGLASGSLQVVATDHCAFTTEQKRFGVGDFTRIPNGTGGLEDRMPMLWTYGVATG 354 Query: 368 KMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTHHQAVNFNI 427 ++ N FVAVTSTN AKI N+YP+KG I VG+DAD+V+WDPK ++TISAKT A+++N+ Sbjct: 355 RITMNEFVAVTSTNIAKILNIYPKKGAILVGADADLVVWDPKRSKTISAKTQQSAIDYNV 414 Query: 428 FEGMVCHGVPLVTISRGKVVYEAGVFSVTAGDGKFIPRKPF 468 FEG G+P T++RG V E G G G+F+ R PF Sbjct: 415 FEGKTVTGLPRFTLTRGVVSIEEGTVKTQEGHGEFVRRDPF 455 >4TQT-A nrPDB Length = 497 Score = 451 bits (1160), Expect = e-127, Method: Compositional matrix adjust. Identities = 224/484 (46%), Positives = 312/484 (64%), Gaps = 11/484 (2%) Query: 8 LIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGIDTH 67 +I+GG V+ D + AD+L+EDG + A+G L G V+DA+G V+PGGID H Sbjct: 17 VIKGGTVITADRTFRADILIEDGKIAAIGDSL-------EGDEVIDASGCYVMPGGIDPH 69 Query: 68 THMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWADPKVCC 127 TH+Q PFMG+ S DDF GT AAL+GGTTM++DF +P G+L++A + W A K Sbjct: 70 THLQMPFMGTYSSDDFDTGTAAALAGGTTMVVDFVLPDSEGNLLDALQEWFQKAG-KART 128 Query: 128 DYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEAFSRCKEIGA 187 DYS H+A+T W+++ EM +V+ +G+N+FK FMAYK MV D E++ +F RC E+GA Sbjct: 129 DYSFHMAITGWNERTFNEMAEVVK-RGINTFKHFMAYKGALMVNDDEMFASFQRCAELGA 187 Query: 188 IAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAVNCPLYIV 247 + VHAENGD++A+ K++A G GPE H RP VE EAT RAI IA PLY+V Sbjct: 188 MPLVHAENGDIVAQLQAKLMAEGNDGPEAHAYSRPPEVEGEATNRAIMIADQAGVPLYVV 247 Query: 248 HVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMGPPLRPDPST 307 HV + + + I AR+ G V+GEP+ L D + Y N++W +AA VM PP R D Sbjct: 248 HVSCEQSHEAIRRARQKGMRVFGEPLIQHLTLDESEYHNRDWDYAARRVMSPPFR-DKLN 306 Query: 308 PDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIWEKGVHSG 367 D L LA L TD+C F T QK G +FTKIPNG G+E+RM V+W +GV +G Sbjct: 307 QDSLWAGLAAGSLQCVATDHCAFTTEQKRYGIGNFTKIPNGTGGLEERMPVLWTRGVRTG 366 Query: 368 KMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTHHQAVNFNI 427 ++ N FVAVTSTN AKI N+YP+KG + G+DAD+VIWDP+ T+ ISAKT H ++++N+ Sbjct: 367 RLTPNEFVAVTSTNIAKILNIYPQKGAVVPGADADLVIWDPETTKKISAKTQHSSIDYNV 426 Query: 428 FEGMVCHGVPLVTISRGKVVYEAGVFSVTAGDGKFIPRKPFAEYIYKRIKQRDRTCTPTP 487 FEG G+P++T+SRG++ ++ G + GDG+FI R+P + + + Q P Sbjct: 427 FEGFELKGLPIMTLSRGRIAFDKGQVTAKPGDGRFIEREPNGA-VNRALSQWKEIVAPRK 485 Query: 488 VERA 491 VER+ Sbjct: 486 VERS 489 >1YNY-A nrPDB Length = 461 Score = 370 bits (949), Expect = e-103, Method: Compositional matrix adjust. Identities = 204/463 (44%), Positives = 277/463 (59%), Gaps = 8/463 (1%) Query: 9 IRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGIDTHT 68 IRGG VV + ADVL+E V A+GH L + G +DA G V+PGGID HT Sbjct: 5 IRGGTVVTAADTYQADVLIEGERVVAIGHQL-----SVNGAEEIDATGCYVIPGGIDPHT 59 Query: 69 HMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWADPKVCCD 128 H+ PF G+ + DDF GT+AA GGTT I+DF + +KG SL A TW A K D Sbjct: 60 HLDMPFGGTVTADDFFTGTRAAAFGGTTSIVDFCLTKKGESLKSAIATWHEKARGKAVID 119 Query: 129 YSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEAFSRCKEIGAI 188 Y H+ + +DQV EE++ ++ +G+ S K+FMAYK+++ D L++ + KE+GA+ Sbjct: 120 YGFHLMIAEANDQVLEELESVISSEGITSLKVFMAYKNVFQADDETLFKTLVKAKELGAL 179 Query: 189 AQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAVNCPLYIVH 248 QVHAENGD++ KK LA G T P H RP E EAT RAI + + LY+VH Sbjct: 180 VQVHAENGDVLDYLTKKALAEGNTDPIYHAYTRPPEAEGEATGRAIALTALAGSQLYVVH 239 Query: 249 VMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMGPPLRPDPSTP 308 V SA + IA+AR G VYGE L D ++ A +V PPLR + Sbjct: 240 VSCASAVQRIAEAREKGWNVYGETCPQYLALD-VSIMDQPDFEGAKYVWSPPLR-EKWNQ 297 Query: 309 DFLMNLLANDDLTTTGTDNCTFN-TCQKALGKDDFTKIPNGVNGVEDRMSVIWEKGVHSG 367 + L + L N L T G+D+C FN QK LG+ DFTKIPNG +EDR+++++ +GV G Sbjct: 298 EVLWSALKNGILQTVGSDHCPFNFRGQKELGRGDFTKIPNGGPLIEDRLTILYSEGVRQG 357 Query: 368 KMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTHHQAVNFNI 427 ++ N+FV ++ST AAK+F ++PRKG IAVGSDADIVI+DP RT+S +THH V++N Sbjct: 358 RISLNQFVDISSTKAAKLFGMFPRKGTIAVGSDADIVIFDPHVKRTLSVETHHMNVDYNP 417 Query: 428 FEGMVCHGVPLVTISRGKVVYEAGVFSVTAGDGKFIPRKPFAE 470 FEGM +G + +SRG V F AG G++I R F + Sbjct: 418 FEGMEVYGEVVSVLSRGSFVVRDKQFVGQAGSGQYIKRTTFEQ 460 >3SFW-A nrPDB Length = 461 Score = 368 bits (944), Expect = e-102, Method: Compositional matrix adjust. Identities = 207/462 (44%), Positives = 276/462 (59%), Gaps = 8/462 (1%) Query: 9 IRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGIDTHT 68 IR G VV + ADVL++ V A+G DL V+DA G +LPGGID HT Sbjct: 5 IRNGTVVTASDTYQADVLIDGEKVVAIGSDL-----QATDAEVIDATGYYLLPGGIDPHT 59 Query: 69 HMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWADPKVCCD 128 H+ PF G+ + D+F GTKAA GGTT I+DF + KG SL A TW A K D Sbjct: 60 HLDMPFGGTVTSDNFFTGTKAAAFGGTTSIVDFCLTSKGESLHSAIATWHEKARGKAVID 119 Query: 129 YSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEAFSRCKEIGAI 188 Y H+ V+ +D V EE++ +V ++G+ S K+FMAYK++ M D L++ R KE+GA+ Sbjct: 120 YGFHLMVSDANDHVLEELESVVNNEGITSLKVFMAYKNVLMADDETLFKTLIRAKELGAL 179 Query: 189 AQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAVNCPLYIVH 248 QVHAENGD++ K+ LA G T P H RP E EAT RAI + + + LY+VH Sbjct: 180 VQVHAENGDVLDYLTKQALAEGNTDPIYHAYTRPPEAEGEATGRAIALTALADAQLYVVH 239 Query: 249 VMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMGPPLRPDPSTP 308 V A + IA+AR G VYGE L D T ++ A +V PPLR + Sbjct: 240 VSCADAVRRIAEAREKGWNVYGETCPQYLVLDITALEKPDF-EGAKYVWSPPLR-EKWNQ 297 Query: 309 DFLMNLLANDDLTTTGTDNCTFN-TCQKALGKDDFTKIPNGVNGVEDRMSVIWEKGVHSG 367 D L + L N L T G+D+C FN + QK LG+ DFTKIPNG +EDRM++++ +GV G Sbjct: 298 DVLWSALKNGILQTVGSDHCPFNFSGQKELGRRDFTKIPNGGPIIEDRMTILFSEGVRKG 357 Query: 368 KMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTHHQAVNFNI 427 K+ N+FV +TST AK+F ++P+KG IAVGSDADIV++DP RTIS +THH V++N Sbjct: 358 KISLNQFVDITSTKVAKLFGMFPQKGTIAVGSDADIVLFDPTVQRTISVETHHMNVDYNP 417 Query: 428 FEGMVCHGVPLVTISRGKVVYEAGVFSVTAGDGKFIPRKPFA 469 FEGM HG + +SRG V F AG G+++ R FA Sbjct: 418 FEGMQVHGDVISVLSRGAFVVRNKQFVGHAGAGRYVKRSTFA 459 >1K1D-A nrPDB Length = 460 Score = 351 bits (900), Expect = 6e-97, Method: Compositional matrix adjust. Identities = 195/463 (42%), Positives = 270/463 (58%), Gaps = 8/463 (1%) Query: 8 LIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGIDTH 67 +I+ G +V + A +L++DG + +G +L G V+DA G V PGGID H Sbjct: 4 IIKNGTIVTATDTYEAHLLIKDGKIAMIGQNL-----EEKGAEVIDAKGCYVFPGGIDPH 58 Query: 68 THMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWADPKVCC 127 TH+ P G+ + DDF GT AA GGTT IIDF + KG L +A ETW + A+ K Sbjct: 59 THLDMPLGGTVTKDDFESGTIAAAFGGTTTIIDFCLTNKGEPLKKAIETWHNKANGKAVI 118 Query: 128 DYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEAFSRCKEIGA 187 DY H+ ++ +D V EE+ +++++G+ S K+FMAYK+++ D LY KE+GA Sbjct: 119 DYGFHLMISEITDDVLEELPKVLEEEGITSLKVFMAYKNVFQADDGTLYCTLLAAKELGA 178 Query: 188 IAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAVNCPLYIV 247 + VHAENGD+I KK LA G T P H L RP +E EAT RA + LY+V Sbjct: 179 LVMVHAENGDVIDYLTKKALADGNTDPIYHALTRPPELEGEATGRACQLTELAGSQLYVV 238 Query: 248 HVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMGPPLRPDPST 307 HV A + IA+AR G V+GE L D + Y K A +V PPLR + Sbjct: 239 HVTCAQAVEKIAEARNKGLDVWGETCPQYLVLDQS-YLEKPNFEGAKYVWSPPLR-EKWH 296 Query: 308 PDFLMNLLANDDLTTTGTDNCTFN-TCQKALGKDDFTKIPNGVNGVEDRMSVIWEKGVHS 366 + L N L N L T G+D C+F+ QK LG+ DFTKIPNG +EDR+S+++ +GV Sbjct: 297 QEVLWNALKNGQLQTLGSDQCSFDFKGQKELGRGDFTKIPNGGPIIEDRVSILFSEGVKK 356 Query: 367 GKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTHHQAVNFN 426 G++ N+FV + ST AK+F L+P+KG I VGSDAD+VI+DP R ISA+THH AV++N Sbjct: 357 GRITLNQFVDIVSTRIAKLFGLFPKKGTIVVGSDADLVIFDPNIERVISAETHHMAVDYN 416 Query: 427 IFEGMVCHGVPLVTISRGKVVYEAGVFSVTAGDGKFIPRKPFA 469 FEGM G P+ + RG+ V F G G+++ R + Sbjct: 417 AFEGMKVTGEPVSVLCRGEFVVRDKQFVGKPGYGQYLKRAKYG 459 >1GKQ-A nrPDB Length = 458 Score = 344 bits (883), Expect = 5e-95, Method: Compositional matrix adjust. Identities = 187/461 (40%), Positives = 265/461 (57%), Gaps = 7/461 (1%) Query: 7 LLIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGIDT 66 LLI+ G ++ D AD+ E + +G +L AP G V+DA GK V PG ID Sbjct: 2 LLIKNGEIITADSRYKADIYAEGETITRIGQNL----EAPPGTEVIDATGKYVFPGFIDP 57 Query: 67 HTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWADPKVC 126 H H+ PFM + + D G+KAAL GGTT I+ P + +E ++ W+S A+ Sbjct: 58 HVHIYLPFMATFAKDTHETGSKAALMGGTTTYIEMCCPSRNDDALEGYQLWKSKAEGNSY 117 Query: 127 CDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEAFSRCKEIG 186 CDY+ H+AV+ + ++ + +++ +V D G++SFK+F++YK+ + V D E+Y+ KE+G Sbjct: 118 CDYTFHMAVSKFDEKTEGQLREIVAD-GISSFKIFLSYKNFFGVDDGEMYQTLRLAKELG 176 Query: 187 AIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAVNCPLYI 246 I H EN +L+ +K+L+ G TGPE HE RPEAVEAE T R T Y+ Sbjct: 177 VIVTAHCENAELVGRLQQKLLSEGKTGPEWHEPSRPEAVEAEGTARFATFLETTGATGYV 236 Query: 247 VHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMGPPLRPDPS 306 VH+ K A A+ G +Y E + D T Y + A ++M PPLR D Sbjct: 237 VHLSCKPALDAAMAAKARGVPIYIESVIPHFLLDKT-YAERGGVEAMKYIMSPPLR-DKR 294 Query: 307 TPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIWEKGVHS 366 L + LA + T GTD+C F+T QK LGK+ FT IPNG+ +EDR+++++ GV Sbjct: 295 NQKVLWDALAQGFIDTVGTDHCPFDTEQKLLGKEAFTAIPNGIPAIEDRVNLLYTYGVSR 354 Query: 367 GKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTHHQAVNFN 426 G++D +RFV ST AAK+F L+PRKG IAVGSDAD+V++DP+ TIS KT H ++N Sbjct: 355 GRLDIHRFVDAASTKAAKLFGLFPRKGTIAVGSDADLVVYDPQYRGTISVKTQHVNNDYN 414 Query: 427 IFEGMVCHGVPLVTISRGKVVYEAGVFSVTAGDGKFIPRKP 467 FEG G P V RGKV G F G GK + R+P Sbjct: 415 GFEGFEIDGRPSVVTVRGKVAVRDGQFVGEKGWGKLLRREP 455 >1NFG-A nrPDB Length = 457 Score = 291 bits (745), Expect = 5e-79, Method: Compositional matrix adjust. Identities = 175/472 (37%), Positives = 256/472 (54%), Gaps = 25/472 (5%) Query: 7 LLIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGIDT 66 ++I+ G +V D AD+ ++DG + +G L P R +DAAG+ V PGGID Sbjct: 3 IIIKNGTIVTADGISRADLGIKDGKITQIGGALGP------AERTIDAAGRYVFPGGIDV 56 Query: 67 HTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWADPKVC 126 HTH++ ++S D F T AA GGTT I+DF +G SL EA W A K Sbjct: 57 HTHVETVSFNTQSADTFATATVAAACGGTTTIVDFCQQDRGHSLAEAVAKWDGMAGGKSA 116 Query: 127 CDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEAFSRCKEIG 186 DY H+ V +D V EE+++L D G+ SFK+FMAY+ + M+ D+ L + + + G Sbjct: 117 IDYGYHIIVLDPTDSVIEELEVL-PDLGITSFKVFMAYRGMNMIDDVTLLKTLDKAVKTG 175 Query: 187 AIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAVNCPLYI 246 ++ VHAENGD K +A G T P H L RP VEAEAT RA+ +A VN P+YI Sbjct: 176 SLVMVHAENGDAADYLRDKFVAEGKTAPIYHALSRPPRVEAEATARALALAEIVNAPIYI 235 Query: 247 VHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYW-------NKEWHHAAHHVMGP 299 VHV + + + + A+ G +L THY + A +V P Sbjct: 236 VHVTCEESLEEVMRAKSRG--------VRALAETCTHYLYLTKEDLERPDFEGAKYVFTP 287 Query: 300 PLRPDPSTPDFLMNLLANDDLTTTGTDNCT-FNTCQKALGKDDFTKIPNGVNGVEDRMSV 358 P R D L N L N T +D+C+ K G++DF IPNG GVE+R+ + Sbjct: 288 PARAKKDH-DVLWNALRNGVFETVSSDHCSWLFKGHKDRGRNDFRAIPNGAPGVEERLMM 346 Query: 359 IWEKGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKT 418 +++ GV+ G++ +FV + +T AK+F ++P+KG IAVGSDADIV+WDP+ I Sbjct: 347 VYQ-GVNEGRISLTQFVELVATRPAKVFGMFPQKGTIAVGSDADIVLWDPEAEMVIEQTA 405 Query: 419 HHQAVNFNIFEGMVCHGVPLVTISRGKVVYEAGVFSVTAGDGKFIPRKPFAE 470 H A++++ +EG GVP + RGKV+ + G + DGKF+ R+ + + Sbjct: 406 MHNAMDYSSYEGHKVKGVPKTVLLRGKVIVDEGSYVGEPTDGKFLKRRKYKQ 457 >2FTY-A nrPDB Length = 559 Score = 211 bits (538), Expect = 4e-55, Method: Compositional matrix adjust. Identities = 155/521 (29%), Positives = 252/521 (48%), Gaps = 68/521 (13%) Query: 7 LLIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGIDT 66 L+I+ G + A++ V +G V+ + + P G+ V+DA G + PGGID Sbjct: 5 LIIKNGIICTASDIYAAEIAVNNGKVQLIAASIDPSLGS----EVIDAEGAFITPGGIDA 60 Query: 67 HTHMQFPF-MGSRSIDDFHQGTKAALSGGTTMIIDFA---IPQKGGS-LIEAFET-WRSW 120 H H+ P + +D T++A++GGTT ++ F+ + +KG S L E+ + + Sbjct: 61 HVHVDEPLKLLGDVVDTMEHATRSAVAGGTTTVVAFSTQDVSKKGPSALAESVKLDVDEY 120 Query: 121 ADPKVCCDYSLHV---AVTWWSDQVKEEMKILVQ----DKGVNSFKMFMAYKDLYMVTDL 173 ++ + CDY LH+ + S + +E + + +Q D GV+S KMFM Y L ++D Sbjct: 121 SEQTLYCDYGLHLILFQIEKPSVEARELLDVQLQAAYNDYGVSSVKMFMTYPGL-QISDY 179 Query: 174 ELYEAFSRCKEIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRA 233 ++ A ++ G +HAENGD++ + + G+T H + RP VE EAT RA Sbjct: 180 DIMSAMYATRKNGFTTMLHAENGDMVKWMIEALEEQGLTDAYYHGVSRPSIVEGEATNRA 239 Query: 234 ITIASAVNCPLYIVHVMSKSAAKVIADARRDGKVVYGE--PIAASLG---TDGTHYWNKE 288 IT+A+ ++ P+ VHV S AA+VI A+ G VY E P A L T H+ E Sbjct: 240 ITLATTMDTPILFVHVSSPQAAEVIKQAQTKGLKVYAETCPQYALLSDAITRCHHHGEVE 299 Query: 289 WHH---------------------AAHHVMGPPLRPDPSTPDFLMNLLANDDLTTTGTDN 327 + + ++ PP+RP+ T + + N T G+D+ Sbjct: 300 SYGVGIDLSSISESPFTNPDDRFIGSKYICSPPIRPE-GTQKSIWKGMNNGTFTIVGSDH 358 Query: 328 CTFNTCQKALGKD-------------DFTKIPNGVNGVEDRMSVIWEKGVHSGKMDEN-R 373 C++N +K +F IPNG+ GV RM ++++ G G + + Sbjct: 359 CSYNYYEKTSTASKHRAFDPENNKNGEFRYIPNGLPGVCTRMPLLYDYGYLRGNLTSMMK 418 Query: 374 FVAVTSTNAAKIFNLYPRKGRIAVG-SDADIVIWDPKGTRT--------ISAKTHHQAVN 424 V + TN AK++ +YP+KG I G SDAD+VIW P ++ I+ K + Sbjct: 419 LVEIQCTNPAKVYGMYPQKGSILPGVSDADLVIWYPDDSKKEYNSKPKLITNKLMEHNCD 478 Query: 425 FNIFEGMVCHGVPLVTISRGKVVYEAGVFSVTAGDGKFIPR 465 + FEG+ P TI +GK+VY+ G DGK++ R Sbjct: 479 YTPFEGIEIKNWPRYTIVKGKIVYKEGEILKENADGKYLKR 519 >1GKR-A nrPDB Length = 458 Score = 171 bits (434), Expect = 6e-43, Method: Compositional matrix adjust. Identities = 138/471 (29%), Positives = 223/471 (47%), Gaps = 29/471 (6%) Query: 7 LLIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGIDT 66 ++++ R+V+ D AD+LV+DG V A+ D + R +DA GK V+PG +D Sbjct: 4 VIVKNCRLVSSDGITEADILVKDGKVAAISADTSDVEAS----RTIDAGGKFVMPGVVDE 59 Query: 67 HTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWADPKVC 126 H H+ + +R F +++A GG T II+ I + ++AF + A ++ Sbjct: 60 HVHIIDMDLKNR-YGRFELDSESAAVGGITTIIEMPITFPPTTTLDAFLEKKKQAGQRLK 118 Query: 127 CDYSLHVA-VTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYM---VTDLELYEAFSRC 182 D++L+ V ++++ + D G FK MA M V+D EL+E F Sbjct: 119 VDFALYGGGVPGNLPEIRK-----MHDAGAVGFKSMMAASVPGMFDAVSDGELFEIFQEI 173 Query: 183 KEIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAVNC 242 G++ VHAEN +I K++ A G +E +P E EA RA+ + C Sbjct: 174 AACGSVIVVHAENETIIQALQKQIKAAGGKDMAAYEASQPVFQENEAIQRALLLQKEAGC 233 Query: 243 PLYIVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMGPPLR 302 L ++HV + ++I A+ +G+ V+ E G Y N A +GP ++ Sbjct: 234 RLIVLHVSNPDGVELIHQAQSEGQDVHCE--------SGPQYLNITTDDAER--IGPYMK 283 Query: 303 PDPSTPDFLMNL-----LANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMS 357 P MN+ L N + T G+D+ K G D K NG G+E + Sbjct: 284 VAPPVRSAEMNIRLWEQLENGLIDTLGSDHGGHPVEDKEPGWKDVWKAGNGALGLETSLP 343 Query: 358 VIWEKGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAK 417 ++ GV+ G++ R V V AK+F +YP+KG + VGSDAD++I D + A Sbjct: 344 MMLTNGVNKGRLSLERLVEVMCEKPAKLFGIYPQKGTLQVGSDADLLILDLDIDTKVDAS 403 Query: 418 THHQAVNFNIFEGMVCHGVPLVTISRGKVVYEAGVFSVTAGDGKFIPRKPF 468 ++ F+GM G P++T+ RG VV E G V G G+F+ R+ + Sbjct: 404 QFRSLHKYSPFDGMPVTGAPVLTMVRGTVVAEKGEVLVEQGFGQFVTRRNY 454 >3E74-A nrPDB Length = 473 Score = 133 bits (334), Expect = 2e-31, Method: Compositional matrix adjust. Identities = 126/466 (27%), Positives = 206/466 (44%), Gaps = 31/466 (6%) Query: 7 LLIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGIDT 66 L+I+ G V+ ++ + V D+ V+ G + A+G DL G A V+DA+G +V PG +D Sbjct: 25 LIIKNGTVILENEARVVDIAVKGGKIAAIGQDL---GDAK---EVMDASGLVVSPGMVDA 78 Query: 67 HTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEA-FETWRSWADPKV 125 HTH+ P G + + GT+AA GG T +I+ + Q ++ A E A K+ Sbjct: 79 HTHISEP--GRSHWEGYETGTRAAAKGGITTMIEMPLNQLPATVDRASIELKFDAAKGKL 136 Query: 126 CCDYS-LHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAY-------KDLYMVTDLELYE 177 D + L V++ D++ E + + GV FK F+A D V D + ++ Sbjct: 137 TIDAAQLGGLVSYNIDRLHE-----LDEVGVVGFKCFVATCGDRGIDNDFRDVNDWQFFK 191 Query: 178 AFSRCKEIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIA 237 + E+G VH EN + E ++ G + RP E EA R + +A Sbjct: 192 GAQKLGELGQPVLVHCENALICDELGEEAKREGRVTAHDYVASRPVFTEVEAIRRVLYLA 251 Query: 238 SAVNCPLYIVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVM 297 C L++ HV S + + AR++G+ + E D + +E A Sbjct: 252 KVAGCRLHVCHVSSPEGVEEVTRARQEGQDITCESCPHYFVLDTDQF--EEIGTLAK--C 307 Query: 298 GPPLRPDPSTPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMS 357 PP+R D + L N ++ +D+ + C + + K G+ G++ M Sbjct: 308 SPPIR-DLENQKGMWEKLFNGEIDCLVSDH---SPCPPEMKAGNIMKAWGGIAGLQSCMD 363 Query: 358 VIWEKGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAK 417 V++++ V M F + +TNAA IF L +KGRIA G DAD V P + ++ Sbjct: 364 VMFDEAVQKRGMSLPMFGKLMATNAADIFGLQ-QKGRIAPGKDADFVFIQPNSSYVLTND 422 Query: 418 THHQAVNFNIFEGMVCHGVPLVTISRGKVVYEAGVFSVTAGDGKFI 463 + + G TI RG V+Y+ A G+FI Sbjct: 423 DLEYRHKVSPYVGRTIGARITKTILRGDVIYDIEQGFPVAPKGQFI 468 >3HM7-A nrPDB Length = 448 Score = 124 bits (311), Expect = 9e-29, Method: Compositional matrix adjust. Identities = 124/455 (27%), Positives = 196/455 (43%), Gaps = 36/455 (7%) Query: 7 LLIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGG-----APAGLRVLDAAGKLVLP 61 L+IR VV + + ADV + +G+V A+ PG PA +D G + P Sbjct: 8 LIIRSSTVVTETTTYRADVAIRNGIVSAITE----PGSISSDDGPA----IDGTGLHLFP 59 Query: 62 GGIDTHTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLI-EAFETWRSW 120 G +D H H P G + F G+K+ +GG T D + ++ E + R Sbjct: 60 GMVDVHVHFNEP--GRTEWEGFASGSKSLAAGGVTTYFDMPLNSNPPTITREELDKKRQL 117 Query: 121 ADPKVCCDYSLHVAVTWWSDQVKEEMKIL--VQDKGVNSFKMFMA---YKDLYMVTDLEL 175 A+ K DY +W V + L + D GV FK FM+ D D L Sbjct: 118 ANEKSLVDYR------FWGGLVPGNIDHLQDLHDGGVIGFKAFMSECGTDDFQFSHDETL 171 Query: 176 YEAFSRCKEIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAIT 235 + + +G+I VHAE+ +++ + + + RP E EA R + Sbjct: 172 LKGMKKIAALGSILAVHAESNEMVNALTTIAIEEQRLTVKDYSEARPIVSELEAVERILR 231 Query: 236 IASAVNCPLYIVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHH 295 A CP++I HV S+ K I A+ +G V E L + E + A Sbjct: 232 FAQLTCCPIHICHVSSRKVLKRIKQAKGEGVNVSVETCPHYLLFSLDEF--AEIGYLAK- 288 Query: 296 VMGPPLRPDPSTPDFLMNLLAND-DLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVED 354 PPLR D L+A + DL ++ + + + Q GK F ++ G+ G ++ Sbjct: 289 -CAPPLRERQEVEDLWDGLMAGEIDLISS---DHSPSLPQMKTGKTIF-EVWGGIAGCQN 343 Query: 355 RMSVIWEKGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTI 414 ++V+ +G H KM + V + ST AK F LYP+KG I VG++A + D + T+ Sbjct: 344 TLAVMLTEGYHKRKMPLTQIVQLLSTEPAKRFGLYPQKGTIQVGAEASFTLIDLNESYTL 403 Query: 415 SAKTHHQAVNFNIFEGMVCHGVPLVTISRGKVVYE 449 +A + + + G G TI +GK VY+ Sbjct: 404 NASDLYYRHPISPYVGQRFRGKVKHTICQGKHVYQ 438 >3GRI-A nrPDB Length = 424 Score = 105 bits (261), Expect = 6e-23, Method: Compositional matrix adjust. Identities = 113/449 (25%), Positives = 182/449 (40%), Gaps = 37/449 (8%) Query: 8 LIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGIDTH 67 LI+ G+V+ + + AD+L++ V++ + + P G + ++DA G V PG +D H Sbjct: 3 LIKNGKVLQNGELQQADILIDGKVIKQIAPAIEPSNG----VDIIDAKGHFVSPGFVDVH 58 Query: 68 THMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWADPKVCC 127 H++ P G + GTKAA GG T + + +E FE + D Sbjct: 59 VHLREP--GGEYKETIETGTKAAARGGFTTVCPMPNTRPVPDSVEHFEALQKLID----- 111 Query: 128 DYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKD-LYMVTDLELYEAFSRCKEIG 186 D + + + S ++ K LV + F D + + T +YE ++ Sbjct: 112 DNAQVRVLPYASITTRQLGKELVDFPALVKEGAFAFTDDGVGVQTASMMYEGMIEAAKVN 171 Query: 187 AIAQVHAENGDLIAEGA----KKMLALGITGPEGHELCRPEAVEAEATLRAITIASAVNC 242 H E+ LI GA K+ LGI G P E+ R + +A A C Sbjct: 172 KAIVAHCEDNSLIYGGAMHEGKRSKELGIPG-------IPNICESVQIARDVLLAEAAGC 224 Query: 243 PLYIVHVMSKSAAKVIADARRDGKVVYGE--PIAASLGTDGTHYWNKEWHHAAHHVMGPP 300 ++ HV +K + +VI DA+R G V E P L D N A + M PP Sbjct: 225 HYHVCHVSTKESVRVIRDAKRAGIHVTAEVTPHHLLLTEDDIPGNN------AIYKMNPP 278 Query: 301 LRPDPSTPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIW 360 LR L LL + + TD+ +KA K P G+ G E +++ Sbjct: 279 LRSTEDREALLEGLL-DGTIDCIATDHAPHARDEKA---QPMEKAPFGIVGSETAFPLLY 334 Query: 361 EKGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTHH 420 V +G + V + + FNL G + AD+ I D + I + Sbjct: 335 THFVKNGDWTLQQLVDYLTIKPCETFNL--EYGTLKENGYADLTIIDLDSEQEIKGEDFL 392 Query: 421 QAVNFNIFEGMVCHGVPLVTISRGKVVYE 449 + F G +G P++T+ G+V +E Sbjct: 393 SKADNTPFIGYKVYGNPILTMVEGEVKFE 421 >3MPG-A nrPDB Length = 428 Score = 101 bits (252), Expect = 7e-22, Method: Compositional matrix adjust. Identities = 114/452 (25%), Positives = 177/452 (39%), Gaps = 43/452 (9%) Query: 8 LIRGGRVVNDDFSEVA-DVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGIDT 66 L + GR +N++ VA D+LV+DG + + ++ V+D GKL+ PG +D Sbjct: 4 LFKNGRYMNEEGKIVATDLLVQDGKIAKVAENITADNA-----EVIDVNGKLIAPGLVDV 58 Query: 67 HTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWADPKVC 126 H H++ P G + GT AA GG T I + E E ++ K Sbjct: 59 HVHLREP--GGEHKETIETGTLAAAKGGFTTICAMPNTRPVPDCREHMEDLQNRIKEKAH 116 Query: 127 CDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMF---MAYKDLYMVTDLELYEAFSRCK 183 + + A+T Q EM K + +F + +D M + A R Sbjct: 117 VNVLPYGAITVR--QAGSEMTDFETLKELGAFAFTDDGVGVQDASM-----MLAAMKRAA 169 Query: 184 EIGAIAQVHAENGDLIAEGA----KKMLALGITGPEGHELCRPEAVEAEATLRAITIASA 239 ++ H E LI +G K G+ G P E+ R I +A A Sbjct: 170 KLNMAVVAHCEENTLINKGCVHEGKFSEKHGLNGI-------PSVCESVHIARDILLAEA 222 Query: 240 VNCPLYIVHVMSKSAAKVIADARRDGKVVYGE--PIAASLGTDGTHYWNKEWHHAAHHVM 297 +C ++ HV +K + +VI DA+R G V E P L D + + M Sbjct: 223 ADCHYHVCHVSTKGSVRVIRDAKRAGIKVTAEVTPHHLVLCEDDIPSADPNFK------M 276 Query: 298 GPPLRPDPSTPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMS 357 PPLR + LL + + TD+ +KA G + P G+ G E Sbjct: 277 NPPLRGKEDHEALIEGLL-DGTIDMIATDHAPHTAEEKAQG---IERAPFGITGFETAFP 332 Query: 358 VIWEKGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAK 417 +++ V G + + + + A F L GR+ G ADI I D + I Sbjct: 333 LLYTNLVKKGIITLEQLIQFLTEKPADTFGL--EAGRLKEGRTADITIIDLEQEEEIDPT 390 Query: 418 THHQAVNFNIFEGMVCHGVPLVTISRGKVVYE 449 T F G C G P++TI GK+ ++ Sbjct: 391 TFLSKGKNTPFAGWKCQGWPVMTIVGGKIAWQ 422 >2Z00-A nrPDB Length = 426 Score = 73.2 bits (178), Expect = 3e-13, Method: Compositional matrix adjust. Identities = 107/466 (22%), Positives = 179/466 (38%), Gaps = 65/466 (13%) Query: 7 LLIRGGRVVNDDFSE-VADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGID 65 +LIR R+V+ ADVL+ +G + +L GG +V+D G + PG +D Sbjct: 2 ILIRNVRLVDARGERGPADVLIGEGRILSLE------GGE--AKQVVDGTGCFLAPGFLD 53 Query: 66 THTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWADPKV 125 H H++ P G +D G AA+ GG T ++ + EA + A K Sbjct: 54 LHAHLREP--GEEVKEDLFSGLLAAVRGGYTDLVSMPNTKPPVDTPEAVRALKEKA--KA 109 Query: 126 CCDYSLHVAVTWWSDQ----------VKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLEL 175 LH A Q ++E +L+ D G + + L M L Sbjct: 110 LGLARLHPAAALTEKQEGKTLTPAGLLREAGAVLLTDDGRTNEDAGVLAAGLLMAAPL-- 167 Query: 176 YEAFSRCKEIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRP-EAVEAEA----- 229 G VHAE+ L G GP L P EAEA Sbjct: 168 ----------GLPVAVHAEDAGLRRNGVMN------DGPLADLLGLPGNPPEAEAARIAR 211 Query: 230 ---TLRAITIASAVNCPLYIVHVMSKSAAKVIADARRDGKVVYGE--PIAASLGTDGTHY 284 LR S L++ H+ +K +++ +A+R G V E P +L + Sbjct: 212 DLEVLRYALRRSPATPRLHVQHLSTKRGLELVREAKRAGLPVTAEATPHHLTLTEEALRT 271 Query: 285 WNKEWHHAAHHVMGPPLRPDPSTPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTK 344 ++ + + PPLR + L LL + L TD+ +K + D + Sbjct: 272 FDPLFK------VAPPLRGEEDREALLEGLL-DGTLDAIATDHAPHTLAEK---EKDLLR 321 Query: 345 IPNGVNGVEDRMSVIWEKGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIV 404 P G+ +E +++ + R V + + ++ L P + G++A +V Sbjct: 322 APFGIPSLEVAFPLLYTELHLKRGFPLQRLVELFTDGPRRVLGLPPL--HLEEGAEASLV 379 Query: 405 IWDPKGTRTISAKTHHQAVNFNIFEGMVCHGVPLVTISRGKVVYEA 450 + PK R + ++ + G V G P++T+ G++V+EA Sbjct: 380 LLSPK-ERPVDPSAFASKARYSPWAGWVLGGWPVLTLVAGRIVHEA 424 >1XRT-A nrPDB Length = 467 Score = 66.6 bits (161), Expect = 3e-11, Method: Compositional matrix adjust. Identities = 104/465 (22%), Positives = 190/465 (40%), Gaps = 67/465 (14%) Query: 6 RLLIRGGRVVN--DDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGG 63 +L+++ G V++ + D+LVE+G ++ + ++L P ++DA G +V PG Sbjct: 48 KLIVKNGYVIDPSQNLEGEFDILVENGKIKKIDKNILVPEA-----EIIDAKGLIVCPGF 102 Query: 64 IDTHTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWADP 123 ID H H++ P G +D G++ A++GG T I+ +P + D Sbjct: 103 IDIHVHLRDP--GQTYKEDIESGSRCAVAGGFTTIV--CMPNTNPPI-----------DN 147 Query: 124 KVCCDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLE--------- 174 +Y L + + +V I KG F + K+ V + Sbjct: 148 TTVVNYILQKSKSVGLCRVLPTGTITKGRKG-KEIADFYSLKEAGCVAFTDDGSPVMDSS 206 Query: 175 -LYEAFSRCKEIGAIAQVHAENGDL----IAEG-AKKMLALGITGPEGHELCRPEAVEAE 228 + +A ++G H E+ L I EG +L L PE E+ Sbjct: 207 VMRKALELASQLGVPIMDHCEDDKLAYGVINEGEVSALLGLSSRAPEAEEI--------- 257 Query: 229 ATLRAITIASAVNCPLYIVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKE 288 R +A ++I HV +K + ++I + G I + + + +E Sbjct: 258 QIARDGILAQRTGGHVHIQHVSTKLSLEIIEFFKEKGV-----KITCEVNPNHLLFTERE 312 Query: 289 -WHHAAHHVMGPPLRPDPSTPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPN 347 + A+ + PPLR L+ + + TD+ T +K L +F +P Sbjct: 313 VLNSGANARVNPPLRKKEDRLA-LIEGVKRGIIDCFATDHAPHQTFEKEL--VEFA-MP- 367 Query: 348 GVNGVEDRMSV---IWEKGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIV 404 G+ G++ + ++ KG+ S K + + + + N A+I + G + +GS ADI Sbjct: 368 GIIGLQTALPSALELYRKGIISLK----KLIEMFTINPARIIGV--DLGTLKLGSPADIT 421 Query: 405 IWDPKGTRTISAKTHHQAVNFNIFEGMVCHGVPLVTISRGKVVYE 449 I+DP ++ +T+ G V G + TI GK+VY+ Sbjct: 422 IFDPNKEWILNEETNLSKSRNTPLWGKVLKGKVIYTIKDGKMVYK 466 >2GWN-A nrPDB Length = 452 Score = 53.5 bits (127), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 87/453 (19%), Positives = 172/453 (37%), Gaps = 28/453 (6%) Query: 6 RLLIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGID 65 ++L+R + N+ + V+++ + + LP + V++ +G + PG ID Sbjct: 5 KILLRNALITNEGKTFPGSVMIDGAFISRIIEGELPADDNLSADEVIECSGLRLFPGCID 64 Query: 66 THTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWADPKV 125 H + P + ++ ++AA++GG T +D ++ E R Sbjct: 65 DQVHFREPGLTHKAT--IASESRAAVAGGVTSFMDMPNTNPPTTMWERLLEKRQIGADTA 122 Query: 126 CCDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLE--LYEAFSRCK 183 +Y T +D + E + V V K+F+ M+ D + L + F C Sbjct: 123 WANYGFFFGGT--NDNIDEIKR--VDKHLVPGLKLFLGSSTGNMLVDNKETLEKIFGECD 178 Query: 184 EIGAIAQVHAENGDLIAEGAKKMLA-----LGITGPEGHELCRPEAVEAEATLRAITIAS 238 + A H E ++I + A L I H L R E ++ A+ +A Sbjct: 179 LLIA---THCEKEEIIRANKEHYKAKYGNDLDI---HFHPLIRSEEACYRSSAEAVELAE 232 Query: 239 AVNCPLYIVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMG 298 +N L+I+H+ ++ + R+ + I + + + + ++ + + Sbjct: 233 RMNARLHILHLSTEKELSLF----RNDIPTAQKRITSEVCVHHLWFSDTDYGRLGNRIKW 288 Query: 299 PPLRPDPSTPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSV 358 P S + L + N + TD+ +K + + +G V+ + Sbjct: 289 NPAIKKESDREALRAAVRNGRIDIIATDHAPHLLREK---EGSCLQAASGGPLVQHSLLA 345 Query: 359 IWEKGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKT 418 + E + G V+ T+ A +F + ++G I G AD+V+ DP T+SA Sbjct: 346 LLEL-CNQGIFSIEEIVSKTAHIPATLFAI-EKRGYIRPGYYADLVLVDPSSPHTVSADN 403 Query: 419 HHQAVNFNIFEGMVCHGVPLVTISRGKVVYEAG 451 ++ FEG T G + Y G Sbjct: 404 ILSLCGWSPFEGFTFSHSVAYTFVNGCLAYAKG 436 >6HG1-A nrPDB Length = 371 Score = 44.7 bits (104), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 31/84 (36%), Positives = 45/84 (53%), Gaps = 7/84 (8%) Query: 56 GKLV-LPGGIDTHTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIE-- 112 KLV LPG ID H H++ P G +DF GT AAL+GG TM+ A+P +I+ Sbjct: 1 AKLVRLPGLIDVHVHLREP--GGTHKEDFASGTAAALAGGITMVC--AMPNTRPPIIDAP 56 Query: 113 AFETWRSWADPKVCCDYSLHVAVT 136 A + A+ CD++L + + Sbjct: 57 ALALAQKLAEAGARCDFALFLGAS 80 Score = 31.6 bits (70), Expect = 0.85, Method: Compositional matrix adjust. Identities = 28/125 (22%), Positives = 53/125 (42%), Gaps = 9/125 (7%) Query: 343 TKIPNGVNGVEDRMSVIWEKGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDAD 402 ++ P G G+E + ++ V G++ + + N +IF+L P++ D Sbjct: 242 SRPPPGFPGLETMLPLLL-TAVSEGRLSLDDLLQRLHHNPRRIFHLPPQE-------DTY 293 Query: 403 IVIWDPKGTRTISAKTHHQAVNFNIFEGMVCHGVPLVTISRGKVVYEAGVFSVTAGDGKF 462 + + D + TI + ++ FEG G + RG+V Y G V G G+ Sbjct: 294 VEV-DLEHEWTIPSHMPFSKAHWTPFEGQKVKGTVRRVVLRGEVAYIDGQVLVPPGYGQD 352 Query: 463 IPRKP 467 + + P Sbjct: 353 VRKWP 357 >2VUN-A nrPDB Length = 386 Score = 40.8 bits (94), Expect = 0.001, Method: Compositional matrix adjust. Identities = 33/107 (30%), Positives = 54/107 (50%), Gaps = 11/107 (10%) Query: 5 SRLLIRG-GRVVNDDFS----EVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLV 59 S+ +I+ G++V+ D + ++VEDG++ A+G + L A ++DAAG V Sbjct: 2 SKTIIKNIGKIVSGDIKSPVLQADTIVVEDGLIAAIGGEELMKDAGDA--TIIDAAGSTV 59 Query: 60 LPGGIDTHTHMQ-FPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQ 105 PG +DTH H+ + + DF +AL GG T +I P Sbjct: 60 TPGLLDTHVHVSGGDYAPRQKTMDF---ISSALHGGVTTMISAGSPH 103 >1FWC-C nrPDB Length = 567 Score = 40.0 bits (92), Expect = 0.002, Method: Compositional matrix adjust. Identities = 31/82 (37%), Positives = 41/82 (50%), Gaps = 16/82 (19%) Query: 23 ADVLVEDGVVRALGH----DLLPPGGAPAG--LRVLDAAGKLVLPGGIDTHTHMQFPFMG 76 AD+ V+DG + A+G D+ P P G V+ A GK+V GGIDTH H P Sbjct: 84 ADIGVKDGRIFAIGKAGNPDIQPNVTIPIGAATEVIAAEGKIVTAGGIDTHIHWICP--- 140 Query: 77 SRSIDDFHQGTKAALSGGTTMI 98 Q +A +SG TTM+ Sbjct: 141 -------QQAEEALVSGVTTMV 155 Score = 28.9 bits (63), Expect = 5.5, Method: Compositional matrix adjust. Identities = 13/36 (36%), Positives = 19/36 (52%) Query: 373 RFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDP 408 R++A + N A + G I VG AD+V+W P Sbjct: 402 RYIAKYTINPALTHGIAHEVGSIEVGKLADLVVWSP 437 >4V1Y-A nrPDB Length = 494 Score = 39.3 bits (90), Expect = 0.005, Method: Compositional matrix adjust. Identities = 28/61 (45%), Positives = 38/61 (62%), Gaps = 11/61 (18%) Query: 13 RVVNDDFSEVADVLVEDGVVRALG--HDLLPPGGAPAGLRVLDAAGKLVLPGGIDTHTHM 70 RV+ D + V V+DG + ALG + +PP PA RV+DA GK+VLPG I+ HTH+ Sbjct: 39 RVLGDSW-----VHVQDGRIVALGVHAESVPP---PAD-RVIDARGKVVLPGFINAHTHV 89 Query: 71 Q 71 Sbjct: 90 N 90 >2VHL-A nrPDB Length = 396 Score = 37.4 bits (85), Expect = 0.014, Method: Compositional matrix adjust. Identities = 16/29 (55%), Positives = 21/29 (72%) Query: 377 VTSTNAAKIFNLYPRKGRIAVGSDADIVI 405 +TS NAAK ++ RKG + VG DAD+VI Sbjct: 342 ITSENAAKQLGIFDRKGSVTVGKDADLVI 370 >5T5I-A nrPDB Length = 569 Score = 36.6 bits (83), Expect = 0.028, Method: Compositional matrix adjust. Identities = 22/68 (32%), Positives = 36/68 (52%), Gaps = 12/68 (17%) Query: 6 RLLIRGGRV---VNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPG 62 +I+ G V +N E D+ V+DG + D +V+DA+GK+V+PG Sbjct: 2 EYIIKNGFVYCPLNGVDGEKMDICVKDGKIVESVSD---------SAKVIDASGKIVMPG 52 Query: 63 GIDTHTHM 70 G+D H+H+ Sbjct: 53 GVDPHSHI 60 Score = 32.0 bits (71), Expect = 0.65, Method: Compositional matrix adjust. Identities = 13/31 (41%), Positives = 20/31 (64%) Query: 377 VTSTNAAKIFNLYPRKGRIAVGSDADIVIWD 407 +T +AK+ L KG + VG+DADI ++D Sbjct: 441 ITRATSAKVLGLSDTKGHLGVGADADIAVYD 471 >1RK6-A nrPDB Length = 496 Score = 35.4 bits (80), Expect = 0.053, Method: Compositional matrix adjust. Identities = 27/70 (38%), Positives = 39/70 (55%), Gaps = 7/70 (10%) Query: 2 AAPSRLLIRGGRVVNDDFS--EVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLV 59 A P ++ GG V++ + +ADV V + A+G DL A + R +D AGK+V Sbjct: 18 ATPFDYILSGGTVIDGTNAPGRLADVGVRGDRIAAVG-DL----SASSARRRIDVAGKVV 72 Query: 60 LPGGIDTHTH 69 PG ID+HTH Sbjct: 73 SPGFIDSHTH 82 >3MKV-A nrPDB Length = 426 Score = 35.0 bits (79), Expect = 0.087, Method: Compositional matrix adjust. Identities = 20/67 (29%), Positives = 35/67 (52%), Gaps = 7/67 (10%) Query: 7 LLIRGGRVVNDDFSEVA---DVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGG 63 L R G +++ D ++ ++L+EDG +R + + A V+D GK ++PG Sbjct: 6 FLFRNGALLDPDHPDLLQGFEILIEDGFIREVSDKPIKSSNA----HVIDVKGKTIMPGL 61 Query: 64 IDTHTHM 70 ID H H+ Sbjct: 62 IDLHVHV 68 >3OOQ-A nrPDB Length = 396 Score = 34.7 bits (78), Expect = 0.098, Method: Compositional matrix adjust. Identities = 16/47 (34%), Positives = 26/47 (55%), Gaps = 5/47 (10%) Query: 24 DVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGIDTHTHM 70 DVLV +G V +G ++ P ++D GK + PG +D H+H+ Sbjct: 25 DVLVSNGKVEKVGENIEDPDA-----EIVDLTGKFLFPGFVDAHSHI 66 Score = 34.3 bits (77), Expect = 0.12, Method: Compositional matrix adjust. Identities = 15/36 (41%), Positives = 20/36 (55%) Query: 371 ENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIW 406 E + + + N AKI L R G I G DAD+V+W Sbjct: 329 EEDLLKILTVNPAKILGLEDRIGSIEPGKDADLVVW 364 >2BB0-A nrPDB Length = 421 Score = 34.3 bits (77), Expect = 0.13, Method: Compositional matrix adjust. Identities = 23/58 (39%), Positives = 33/58 (56%), Gaps = 7/58 (12%) Query: 26 LVEDGVVRALGHDLLPPG--GAPAGLR---VLDAAGKLVLPGGIDTHTHMQFPFMGSR 78 ++ED VV ++ G GA AG ++D +G+LV PG +D HTH+ F GSR Sbjct: 34 VIEDAVVGIHEQKIVFAGQKGAEAGYEADEIIDCSGRLVTPGLVDPHTHLVFG--GSR 89 >2OOF-A nrPDB Length = 416 Score = 33.9 bits (76), Expect = 0.17, Method: Compositional matrix adjust. Identities = 25/74 (33%), Positives = 38/74 (51%), Gaps = 13/74 (17%) Query: 53 DAAGKLVLPGGIDTHTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFA-IPQKGGSLI 111 D GKLV PG ID HTH+ F GSR+ ++F K + +A I +KGG +I Sbjct: 58 DMKGKLVTPGLIDCHTHLIFA--GSRA-EEFELRQKG---------VPYAEIARKGGGII 105 Query: 112 EAFETWRSWADPKV 125 R+ ++ ++ Sbjct: 106 STVRATRAASEDQL 119 >3K7I-B nrPDB Length = 187 Score = 33.9 bits (76), Expect = 0.18, Method: Compositional matrix adjust. Identities = 32/118 (27%), Positives = 52/118 (44%), Gaps = 3/118 (2%) Query: 307 TPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIW-EKGVH 365 TP++ +++ D+ TG D C+ L + + N GV+ R++ W E G H Sbjct: 67 TPNYNPDIIFKDE-ENTGADRLMTQRCKDRLNSLAIS-VMNQWPGVKLRVTKGWDEDGHH 124 Query: 366 SGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTHHQAV 423 S + AV T + + N Y R+AV + D V ++ K S K+ H A Sbjct: 125 SEESLHYEGRAVDITTSDRDRNKYGLLARLAVEAGFDWVYYESKAHVHCSVKSEHSAA 182 >6ASO-A nrPDB Length = 424 Score = 33.5 bits (75), Expect = 0.22, Method: Compositional matrix adjust. Identities = 28/102 (27%), Positives = 44/102 (43%), Gaps = 13/102 (12%) Query: 228 EATLRAITIASAVNCPLYIVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNK 287 E +R I + S N + I+ SK AAK++ +G G+ I + D Y+N Sbjct: 314 EKDIRKILLVSDFNGAI-IIFRDSKFAAKMLMIL--NGSQFQGKVIRSGTINDMKRYYNN 370 Query: 288 EWHHAAHHV---------MGPPLRPDPSTPDFLMNLLANDDL 320 + +H+ HV GP L+ PD ++NDD Sbjct: 371 QQNHSMKHVKPSCINMMEKGPNLQVKKKIPD-KQEQMSNDDF 411 >6NBO-A nrPDB Length = 402 Score = 33.1 bits (74), Expect = 0.33, Method: Compositional matrix adjust. Identities = 23/64 (35%), Positives = 32/64 (50%), Gaps = 7/64 (10%) Query: 7 LLIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGIDT 66 LLIR R DD D+L+E + G P AP G + + AG + LPG ++ Sbjct: 12 LLIRNVRTGADD---ALDILIEGDRIARTG----PSLDAPPGCAIEEGAGAIALPGLVEG 64 Query: 67 HTHM 70 HTH+ Sbjct: 65 HTHL 68 >2PUZ-A nrPDB Length = 419 Score = 33.1 bits (74), Expect = 0.34, Method: Compositional matrix adjust. Identities = 17/63 (26%), Positives = 27/63 (42%) Query: 368 KMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTHHQAVNFNI 427 +M + T+ NAAK L G + G AD IWD + + + ++ I Sbjct: 352 RMTVEECLTATTRNAAKALGLLAETGTLEAGKSADFAIWDIERPAELVYRIGFNPLHARI 411 Query: 428 FEG 430 F+G Sbjct: 412 FKG 414 >2Z1T-A nrPDB Length = 343 Score = 32.7 bits (73), Expect = 0.34, Method: Compositional matrix adjust. Identities = 20/52 (38%), Positives = 28/52 (53%), Gaps = 1/52 (1%) Query: 414 ISAKTHHQAVNFNIFEGMVCHGVPLVTISRGKVVYEAGVFSVTAGDGKFIPR 465 + A+ + + F + EG+ + V S GK EAGVF VT GD K +PR Sbjct: 85 LGARPRYLSCGFILEEGLDMDILERVVASMGKAAREAGVFIVT-GDTKVVPR 135 >2AQV-A nrPDB Length = 390 Score = 32.7 bits (73), Expect = 0.36, Method: Compositional matrix adjust. Identities = 18/63 (28%), Positives = 34/63 (53%), Gaps = 2/63 (3%) Query: 8 LIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGIDTH 67 L++G + + + DVLV +G + A+ ++ P V+D +G+++ PG ID H Sbjct: 11 LLQGAHLYAPEDRGICDVLVANGKIIAVASNI--PSDIVPNCTVVDLSGQILCPGFIDQH 68 Query: 68 THM 70 H+ Sbjct: 69 VHL 71 >3T8L-A nrPDB Length = 608 Score = 32.7 bits (73), Expect = 0.37, Method: Compositional matrix adjust. Identities = 25/67 (37%), Positives = 36/67 (53%), Gaps = 6/67 (8%) Query: 7 LLIRGGRVVNDDFSEV--ADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGI 64 +LI GG +V+ E+ AD+ G+V AL + P +V+DA G V PG I Sbjct: 37 VLITGGTLVDVVTGELRPADI----GIVGALIASVHEPASRRDAAQVIDAGGAYVSPGLI 92 Query: 65 DTHTHMQ 71 DTH H++ Sbjct: 93 DTHMHIE 99 >3GIQ-A nrPDB Length = 480 Score = 32.7 bits (73), Expect = 0.42, Method: Compositional matrix adjust. Identities = 21/53 (39%), Positives = 27/53 (50%), Gaps = 5/53 (9%) Query: 23 ADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGIDTHTHMQFPFM 75 AD+ V DG + A+G GA DA+GK+V PG ID H H F+ Sbjct: 27 ADLGVRDGRIAAIGEL-----GAHPARHAWDASGKIVAPGFIDVHGHDDLMFV 74 >4CQD-A nrPDB Length = 423 Score = 32.0 bits (71), Expect = 0.73, Method: Compositional matrix adjust. Identities = 13/26 (50%), Positives = 16/26 (61%) Query: 52 LDAAGKLVLPGGIDTHTHMQFPFMGS 77 +DA G LV PG +D HTHM F + Sbjct: 65 IDAKGNLVSPGFVDAHTHMDKSFTST 90 >2P9B-A nrPDB Length = 458 Score = 32.0 bits (71), Expect = 0.76, Method: Compositional matrix adjust. Identities = 22/61 (36%), Positives = 27/61 (44%), Gaps = 16/61 (26%) Query: 46 PAGLRVLDAAGKLVLPGGIDTHTHMQFPFMGSRSIDDFHQGT----KAALSGGTTMIIDF 101 PA LD GK+V+PG I+ HTH+ F QG K A G M+ F Sbjct: 56 PAEYHYLDGTGKIVMPGLINAHTHL------------FSQGKPLNPKLATPKGQRMVATF 103 Query: 102 A 102 A Sbjct: 104 A 104 >3HPA-A nrPDB Length = 479 Score = 31.6 bits (70), Expect = 0.87, Method: Compositional matrix adjust. Identities = 25/72 (34%), Positives = 37/72 (51%), Gaps = 8/72 (11%) Query: 4 PSRLLIRGGRVV---NDDFSEVAD--VLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKL 58 P LL++ V+ +D E+ D + +ED + A+G P A VLD G L Sbjct: 28 PKTLLVKHADVLVTMDDTRRELRDAGLYIEDNRIVAVGPSAELPETAD---EVLDLRGHL 84 Query: 59 VLPGGIDTHTHM 70 V+PG ++TH HM Sbjct: 85 VIPGLVNTHHHM 96 >4CEX-C nrPDB Length = 570 Score = 31.2 bits (69), Expect = 1.0, Method: Compositional matrix adjust. Identities = 22/64 (34%), Positives = 28/64 (43%), Gaps = 18/64 (28%) Query: 23 ADVLVEDGVVRALGHDLLPPGGAP-------------AGLRVLDAAGKLVLPGGIDTHTH 69 AD+ V+DG + +G GG P V+ A GK+V GGIDTH H Sbjct: 85 ADIGVKDGYIVGIGK-----GGNPDIMDGVTPNMIVGTATEVIAAEGKIVTAGGIDTHVH 139 Query: 70 MQFP 73 P Sbjct: 140 FINP 143 >3MTW-A nrPDB Length = 403 Score = 31.2 bits (69), Expect = 1.2, Method: Compositional matrix adjust. Identities = 22/67 (32%), Positives = 34/67 (50%), Gaps = 9/67 (13%) Query: 5 SRLL-IRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGG 63 +RLL + G+ V++ V+V DG + ++G PAG +D G +LPG Sbjct: 9 ARLLDVASGKYVDNPL-----VIVTDGRITSIGK---KGDAVPAGATAVDLPGVTLLPGL 60 Query: 64 IDTHTHM 70 ID H H+ Sbjct: 61 IDMHVHL 67 >2OGJ-A nrPDB Length = 417 Score = 30.4 bits (67), Expect = 2.1, Method: Compositional matrix adjust. Identities = 18/48 (37%), Positives = 27/48 (56%), Gaps = 5/48 (10%) Query: 24 DVLVE-DGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGIDTHTHM 70 D+L+ DG + A+G L APA + +DA G + PG +D H H+ Sbjct: 37 DILIGGDGKIAAVGSALQ----APADTQRIDAKGAFISPGWVDLHVHI 80 >2Y7H-A nrPDB Length = 464 Score = 30.0 bits (66), Expect = 2.5, Method: Compositional matrix adjust. Identities = 22/81 (27%), Positives = 34/81 (41%), Gaps = 10/81 (12%) Query: 353 EDRMSVIWEKGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTR 412 +D + +I + +GK D V V NL +I S DIVI G++ Sbjct: 38 DDYLPLIRANNIQNGKFDTTDLVFVPK-------NLVKESQKI---SPEDIVIAMSSGSK 87 Query: 413 TISAKTHHQAVNFNIFEGMVC 433 ++ K+ HQ + F G C Sbjct: 88 SVVGKSAHQHLPFECSFGAFC 108 >3IGH-X nrPDB Length = 486 Score = 29.6 bits (65), Expect = 3.1, Method: Compositional matrix adjust. Identities = 25/92 (27%), Positives = 39/92 (42%), Gaps = 25/92 (27%) Query: 5 SRLLIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGI 64 S L+I G+V+ SEVA +VE +G ++D GK V+P Sbjct: 22 SGLVISHGKVIYAGDSEVAKKIVE-----------------LSGGEIVDLKGKYVMPAFF 64 Query: 65 DTHTHM--------QFPFMGSRSIDDFHQGTK 88 D+H H+ G++SI++ Q K Sbjct: 65 DSHLHLDELGMSLEMVDLRGAKSIEELIQRLK 96 >4LH8-A nrPDB Length = 469 Score = 29.6 bits (65), Expect = 3.2, Method: Compositional matrix adjust. Identities = 28/89 (31%), Positives = 45/89 (50%), Gaps = 11/89 (12%) Query: 7 LLIRG-GRVVNDDFSEV----ADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLP 61 +LIRG RV+ D E AD+L++ + A+G +L + R +D G + LP Sbjct: 15 ILIRGLTRVITFDDQERELEDADILIDGPKIVAVGKNLSDRSVS----RTIDGRGMIALP 70 Query: 62 GGIDTHTHMQFPFMGSRSIDDFHQGTKAA 90 G I++H H+ M R+I + T A+ Sbjct: 71 GLINSHQHLYEGAM--RAIPQLERVTMAS 97 >3N2C-A nrPDB Length = 423 Score = 29.6 bits (65), Expect = 3.4, Method: Compositional matrix adjust. Identities = 14/29 (48%), Positives = 21/29 (72%) Query: 379 STNAAKIFNLYPRKGRIAVGSDADIVIWD 407 +T AA+I N+ + G IAVG+ AD+V+ D Sbjct: 353 TTVAAEIVNMQGQLGVIAVGAIADLVVLD 381 >4Z42-C nrPDB Length = 572 Score = 29.6 bits (65), Expect = 3.5, Method: Compositional matrix adjust. Identities = 14/37 (37%), Positives = 21/37 (56%) Query: 373 RFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPK 409 R+VA + N A + G + VG AD+V+WDP+ Sbjct: 407 RYVAKITINPAIAQGVSHVIGSVEVGKMADLVLWDPR 443 >3GGM-A nrPDB Length = 81 Score = 29.6 bits (65), Expect = 3.5, Method: Composition-based stats. Identities = 19/66 (28%), Positives = 35/66 (53%), Gaps = 3/66 (4%) Query: 7 LLIRGGRVVNDDFS--EVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGI 64 +++ G++ D S EV+ + + DG++ A+G D L A + +D K +PG Sbjct: 6 MILYNGKITTLDPSQPEVSAIAITDGLITAVGGDEL-LNSATEKTKKIDLKRKRAIPGLN 64 Query: 65 DTHTHM 70 D+H H+ Sbjct: 65 DSHIHV 70 >3QGK-C nrPDB Length = 568 Score = 29.3 bits (64), Expect = 4.0, Method: Compositional matrix adjust. Identities = 19/63 (30%), Positives = 30/63 (47%), Gaps = 12/63 (19%) Query: 23 ADVLVEDGVVRALG---HDLLPPGGAP-----AGLRVLDAAGKLVLPGGIDTHTHM---- 70 AD+ +++G + +G + + G P G L G ++ GGID+HTH Sbjct: 83 ADIGIKNGKIHGIGKAGNKDMQDGVTPHMVVGVGTEALAGEGMIITAGGIDSHTHFLSPQ 142 Query: 71 QFP 73 QFP Sbjct: 143 QFP 145 >5YGQ-A nrPDB Length = 342 Score = 29.3 bits (64), Expect = 4.5, Method: Compositional matrix adjust. Identities = 14/29 (48%), Positives = 19/29 (65%), Gaps = 1/29 (3%) Query: 439 VTISRGKVVYEAGVFSVTAGDGKFIPRKP 467 VT + GKV +E V V AG G F+P++P Sbjct: 102 VTTNAGKV-FECTVLVVAAGGGSFLPKRP 129 >1U83-A nrPDB Length = 276 Score = 29.3 bits (64), Expect = 4.8, Method: Compositional matrix adjust. Identities = 27/110 (24%), Positives = 40/110 (36%), Gaps = 18/110 (16%) Query: 160 MFMAYKDLYMVTDLELYEAFSRCKEI----GAIAQVHAENGDLIAEGAKKMLALGITGPE 215 +F Y V + Y + C+ I G + + E IA+ + + L L G + Sbjct: 102 LFEKYVSQKKVNEFHRYCTYFGCEYIEISNGTLPMTNKEKAAYIADFSDEFLVLSEVGSK 161 Query: 216 GHELCRPEAVEAEATLRAITIASAVNCPLYIVHVMSKSAAKVIADARRDG 265 EL ++ E YIV M A KVI +AR G Sbjct: 162 DAELASRQSSEEWLE--------------YIVEDMEAGAEKVITEARESG 197 >1YQC-A nrPDB Length = 170 Score = 28.9 bits (63), Expect = 5.2, Method: Composition-based stats. Identities = 33/125 (26%), Positives = 46/125 (36%), Gaps = 29/125 (23%) Query: 217 HELCRPEAVEAEATLRAITIASAVNCPLYIVHVMSKSAAKVIADARRDGKVVY------- 269 H+L E +E + TL +I A N PL I H + + A G+V Sbjct: 39 HDLALVEILEQDRTLISINRAQPANLPLTI-HELERHPLGTQAFIPMKGEVFVVVVALGD 97 Query: 270 GEPIAASL------GTDGTHYWNKEWHHAAHHVMGPPLRPDPSTPDFLMNLLANDDLTTT 323 +P ++L G G +Y WHH PL DFL + Sbjct: 98 DKPDLSTLRAFITNGEQGVNYHRNVWHH--------PLFAWQRVTDFLT-------IDRG 142 Query: 324 GTDNC 328 G+DNC Sbjct: 143 GSDNC 147 >1AK1-A nrPDB Length = 310 Score = 28.9 bits (63), Expect = 5.4, Method: Compositional matrix adjust. Identities = 29/99 (29%), Positives = 44/99 (44%), Gaps = 26/99 (26%) Query: 107 GGSLIEAFETWRSWADPKVCCDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKD 166 GG I + E+W + +PK VT+W D+VKE + +D+ N+ + A+ Sbjct: 137 GGLTITSVESW--YDEPKF---------VTYWVDRVKETYASMPEDERENAMLIVSAHS- 184 Query: 167 LYMVTDLELYEAFSRCKEIG--AIAQVHAENGDLIAEGA 203 + KE G Q+H E+ LIAEGA Sbjct: 185 -----------LPEKIKEFGDPYPDQLH-ESAKLIAEGA 211 >2PLM-A nrPDB Length = 406 Score = 28.9 bits (63), Expect = 6.4, Method: Compositional matrix adjust. Identities = 11/18 (61%), Positives = 14/18 (77%) Query: 52 LDAAGKLVLPGGIDTHTH 69 LD +GKLV+P +THTH Sbjct: 40 LDLSGKLVMPALFNTHTH 57 >3ICJ-A nrPDB Length = 534 Score = 28.5 bits (62), Expect = 7.4, Method: Compositional matrix adjust. Identities = 12/35 (34%), Positives = 18/35 (51%) Query: 47 AGLRVLDAAGKLVLPGGIDTHTHMQFPFMGSRSID 81 AG ++D GK V+P D+H H+ M +D Sbjct: 81 AGGEIIDLKGKFVMPAFFDSHLHLDELGMSLEMVD 115 >2GBX-B nrPDB Length = 174 Score = 28.5 bits (62), Expect = 8.3, Method: Compositional matrix adjust. Identities = 14/35 (40%), Positives = 19/35 (54%) Query: 472 IYKRIKQRDRTCTPTPVERAPYKGEVATLKSRVTK 506 IY++ RDR PTP + A Y + LK RV + Sbjct: 50 IYEQRLTRDRRPDPTPDDAAIYNDDFGELKQRVER 84 >2OOD-A nrPDB Length = 475 Score = 28.1 bits (61), Expect = 8.9, Method: Compositional matrix adjust. Identities = 15/52 (28%), Positives = 27/52 (51%), Gaps = 1/52 (1%) Query: 19 FSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGIDTHTHM 70 F + ++V DGV++A G A G+ + ++++PG ID H H+ Sbjct: 32 FHQDGLMVVTDGVIKAFG-PYEKIAAAHPGVEITHIKDRIIVPGFIDGHIHL 82 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 2VR2-A nrPDB 790 0.0 5YZA-A nrPDB 737 0.0 4CNT-A nrPDB 728 0.0 4LCQ-A nrPDB 719 0.0 1KCX-A nrPDB 712 0.0 5NKS-A nrPDB 701 0.0 4CNS-A nrPDB 694 0.0 2FTW-A nrPDB 689 0.0 4B90-A nrPDB 683 0.0 4TQT-A nrPDB 655 0.0 3DC8-A nrPDB 652 0.0 6AJD-A nrPDB 650 0.0 4B91-A nrPDB 645 0.0 1YNY-A nrPDB 623 e-179 1K1D-A nrPDB 621 e-178 3SFW-A nrPDB 621 e-178 1GKQ-A nrPDB 566 e-161 1NFG-A nrPDB 530 e-151 2FTY-A nrPDB 481 e-136 1GKR-A nrPDB 464 e-131 3E74-A nrPDB 455 e-128 3HM7-A nrPDB 438 e-123 3MPG-A nrPDB 423 e-118 3GRI-A nrPDB 419 e-117 2GWN-A nrPDB 411 e-115 1XRT-A nrPDB 369 e-102 2Z00-A nrPDB 349 2e-96 6HG1-A nrPDB 226 2e-59 2VUN-A nrPDB 90 3e-18 Sequences not found previously or not previously below threshold: 3OOQ-A nrPDB 102 4e-22 3GIQ-A nrPDB 87 2e-17 2PUZ-A nrPDB 84 1e-16 1FWC-C nrPDB 79 7e-15 1RK6-A nrPDB 76 5e-14 3QGK-C nrPDB 75 6e-14 2VHL-A nrPDB 74 2e-13 4CEX-C nrPDB 74 2e-13 2ICS-A nrPDB 69 5e-12 4WGX-A nrPDB 68 9e-12 1E9Y-B nrPDB 65 5e-11 4CQD-A nrPDB 65 9e-11 2AQV-A nrPDB 64 1e-10 2OGJ-A nrPDB 64 2e-10 3MKV-A nrPDB 64 2e-10 3IV8-A nrPDB 62 6e-10 3HPA-A nrPDB 61 1e-09 2PLM-A nrPDB 61 1e-09 3DUG-A nrPDB 61 1e-09 4Z42-C nrPDB 60 2e-09 4V1Y-A nrPDB 59 6e-09 3T8L-A nrPDB 57 1e-08 2BB0-A nrPDB 57 3e-08 5T5I-A nrPDB 56 3e-08 4H9M-A nrPDB 56 5e-08 4R7W-A nrPDB 55 5e-08 5XGX-A nrPDB 55 7e-08 1O12-A nrPDB 55 7e-08 5VGM-A nrPDB 55 9e-08 4G7E-B nrPDB 54 1e-07 3N2C-A nrPDB 53 4e-07 4DYK-A nrPDB 52 6e-07 4LH8-A nrPDB 52 6e-07 4F0R-A nrPDB 52 8e-07 4WHB-E nrPDB 51 1e-06 3MTW-A nrPDB 50 2e-06 6NBO-A nrPDB 48 1e-05 1YRR-A nrPDB 45 6e-05 2OOF-A nrPDB 45 7e-05 3GGM-A nrPDB 45 1e-04 3IGH-X nrPDB 44 2e-04 4LFY-A nrPDB 43 3e-04 3ICJ-A nrPDB 43 3e-04 2QS8-A nrPDB 43 4e-04 1R9X-A nrPDB 43 4e-04 2P9B-A nrPDB 42 6e-04 3LNP-A nrPDB 42 8e-04 4DZH-A nrPDB 40 0.002 6CTY-A nrPDB 40 0.002 3JZE-A nrPDB 40 0.003 2OOD-A nrPDB 38 0.012 3MDW-A nrPDB 37 0.027 2I9U-A nrPDB 36 0.038 2PAJ-A nrPDB 36 0.051 2WJF-A nrPDB 35 0.066 6FV3-A nrPDB 34 0.20 5YDJ-A nrPDB 33 0.37 5YDI-A nrPDB 33 0.37 6NRZ-A nrPDB 33 0.39 5JCN-A nrPDB 32 0.47 1S69-A nrPDB 32 0.58 2QIW-A nrPDB 32 0.86 3RZZ-A nrPDB 31 1.5 6ERI-Ad nrPDB 30 2.2 5MLC-5 nrPDB 30 2.2 1Z72-A nrPDB 30 2.8 2QI2-A nrPDB 30 3.4 4WVX-A nrPDB 30 3.4 2OI8-A nrPDB 30 3.5 2YFK-A nrPDB 29 4.7 5WLC-LV nrPDB 29 5.1 1AOS-A nrPDB 29 8.2 >2VR2-A nrPDB Length = 541 Score = 790 bits (2040), Expect = 0.0, Method: Composition-based stats. Identities = 519/519 (100%), Positives = 519/519 (100%) Query: 1 MAAPSRLLIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVL 60 MAAPSRLLIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVL Sbjct: 23 MAAPSRLLIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVL 82 Query: 61 PGGIDTHTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSW 120 PGGIDTHTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSW Sbjct: 83 PGGIDTHTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSW 142 Query: 121 ADPKVCCDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEAFS 180 ADPKVCCDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEAFS Sbjct: 143 ADPKVCCDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEAFS 202 Query: 181 RCKEIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAV 240 RCKEIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAV Sbjct: 203 RCKEIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAV 262 Query: 241 NCPLYIVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMGPP 300 NCPLYIVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMGPP Sbjct: 263 NCPLYIVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMGPP 322 Query: 301 LRPDPSTPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIW 360 LRPDPSTPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIW Sbjct: 323 LRPDPSTPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIW 382 Query: 361 EKGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTHH 420 EKGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTHH Sbjct: 383 EKGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTHH 442 Query: 421 QAVNFNIFEGMVCHGVPLVTISRGKVVYEAGVFSVTAGDGKFIPRKPFAEYIYKRIKQRD 480 QAVNFNIFEGMVCHGVPLVTISRGKVVYEAGVFSVTAGDGKFIPRKPFAEYIYKRIKQRD Sbjct: 443 QAVNFNIFEGMVCHGVPLVTISRGKVVYEAGVFSVTAGDGKFIPRKPFAEYIYKRIKQRD 502 Query: 481 RTCTPTPVERAPYKGEVATLKSRVTKEDATAGTRKQAHP 519 RTCTPTPVERAPYKGEVATLKSRVTKEDATAGTRKQAHP Sbjct: 503 RTCTPTPVERAPYKGEVATLKSRVTKEDATAGTRKQAHP 541 >5YZA-A nrPDB Length = 525 Score = 737 bits (1902), Expect = 0.0, Method: Composition-based stats. Identities = 308/516 (59%), Positives = 385/516 (74%), Gaps = 6/516 (1%) Query: 4 PSRLLIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGG 63 RLLI+GG++VNDD S AD+ +EDG+++ +G +L+ PGG ++ ++A ++V+PGG Sbjct: 14 SDRLLIKGGKIVNDDQSFYADIYMEDGLIKQIGENLIVPGG----VKTIEAHSRMVIPGG 69 Query: 64 IDTHTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWADP 123 ID HT Q P G S DDF QGTKAAL+GGTTMIID +P+ G SL+ AF+ WR WAD Sbjct: 70 IDVHTRFQMPDQGMTSADDFFQGTKAALAGGTTMIIDHVVPEPGTSLLAAFDQWREWADS 129 Query: 124 KVCCDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEAFSRCK 183 K CCDYSLHV ++ W ++EEM+ LV+D GVNSF ++MA+KD + +TD ++YE S + Sbjct: 130 KSCCDYSLHVDISEWHKGIQEEMEALVKDHGVNSFLVYMAFKDRFQLTDCQIYEVLSVIR 189 Query: 184 EIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAVNCP 243 +IGAIAQVHAENGD+IAE +++L LGITGPEGH L RPE VEAEA RAITIA+ NCP Sbjct: 190 DIGAIAQVHAENGDIIAEEQQRILDLGITGPEGHVLSRPEEVEAEAVNRAITIANQTNCP 249 Query: 244 LYIVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMGPPLRP 303 LYI VMSKS+A+VIA AR+ G VVYGEPI ASLGTDG+HYW+K W AA V PPL P Sbjct: 250 LYITKVMSKSSAEVIAQARKKGTVVYGEPITASLGTDGSHYWSKNWAKAAAFVTSPPLSP 309 Query: 304 DPSTPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIWEKG 363 DP+TPDFL +LL+ DL TG+ +CTFNT QKA+GKD+FT IP G NG E+RMSVIW+K Sbjct: 310 DPTTPDFLNSLLSCGDLQVTGSAHCTFNTAQKAVGKDNFTLIPEGTNGTEERMSVIWDKA 369 Query: 364 VHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTHHQAV 423 V +GKMDEN+FVAVTSTNAAK+FNLYPRKGRIAVGSDAD+VIWDP +TISAKTH+ ++ Sbjct: 370 VVTGKMDENQFVAVTSTNAAKVFNLYPRKGRIAVGSDADLVIWDPDSVKTISAKTHNSSL 429 Query: 424 NFNIFEGMVCHGVPLVTISRGKVVYEAGVFSVTAGDGKFIPRKPFAEYIYKRIKQRDRTC 483 +NIFEGM C G PLV IS+GK+V E G VT G G++IPRKPF +++YKRIK R R Sbjct: 430 EYNIFEGMECRGSPLVVISQGKIVLEDGTLHVTEGSGRYIPRKPFPDFVYKRIKARSRLA 489 Query: 484 TPTPVERAPYKGEVATLKSRVTKEDATAGTRKQAHP 519 V R Y G V + VT + T + + P Sbjct: 490 ELRGVPRGLYDGPVCEVS--VTPKTVTPASSAKTDP 523 >4CNT-A nrPDB Length = 570 Score = 728 bits (1879), Expect = 0.0, Method: Composition-based stats. Identities = 303/516 (58%), Positives = 383/516 (74%), Gaps = 6/516 (1%) Query: 4 PSRLLIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGG 63 RLLI+GGR+VNDD S AD+ +EDG+++ +G +L+ PGG ++ ++A GK+V+PGG Sbjct: 14 SDRLLIKGGRIVNDDQSFYADIYMEDGLIKQIGDNLIVPGG----VKTIEANGKMVIPGG 69 Query: 64 IDTHTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWADP 123 ID HTH Q P+ G ++DDF QGTKAAL+GGTTMIID +P+ SL EA+E WR WAD Sbjct: 70 IDVHTHYQMPYKGMTTVDDFFQGTKAALAGGTTMIIDHVVPEPESSLTEAYEKWREWADG 129 Query: 124 KVCCDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEAFSRCK 183 K CCDY+LHV +T W+D VK+E++ L++DKGVNSF ++MAYKDLY V++ ELYE F+ Sbjct: 130 KSCCDYALHVDITHWNDSVKQEVQNLIKDKGVNSFMVYMAYKDLYQVSNTELYEIFTCLG 189 Query: 184 EIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAVNCP 243 E+GAIAQVHAENGD+IA+ +ML +GITGPEGH L RPE +EAEA RAITIAS NCP Sbjct: 190 ELGAIAQVHAENGDIIAQEQTRMLEMGITGPEGHVLSRPEELEAEAVFRAITIASQTNCP 249 Query: 244 LYIVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMGPPLRP 303 LY+ VMSKSAA +I+ AR+ G VV+GEPI ASLG DGTHYW+K W AA V PPL P Sbjct: 250 LYVTKVMSKSAADLISQARKKGNVVFGEPITASLGIDGTHYWSKNWAKAAAFVTSPPLSP 309 Query: 304 DPSTPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIWEKG 363 DP+TPD++ +LLA+ DL +G+ +CTF+T QKA+GKD+FT IP G NGVE+RMSVIW+K Sbjct: 310 DPTTPDYINSLLASGDLQLSGSAHCTFSTAQKAIGKDNFTAIPEGTNGVEERMSVIWDKA 369 Query: 364 VHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTHHQAV 423 V +GKMDEN+FVAVTSTNAAKIFNLYPRKGRI+VGSD+D+VIWDP + +SAK H A Sbjct: 370 VATGKMDENQFVAVTSTNAAKIFNLYPRKGRISVGSDSDLVIWDPDAVKIVSAKNHQSAA 429 Query: 424 NFNIFEGMVCHGVPLVTISRGKVVYEAGVFSVTAGDGKFIPRKPFAEYIYKRIKQRDRTC 483 +NIFEGM G PLV I +GK++ E G VT G G+FIP PF++Y+YKRIK R + Sbjct: 430 EYNIFEGMELRGAPLVVICQGKIMLEDGNLHVTQGAGRFIPCSPFSDYVYKRIKARRKMA 489 Query: 484 TPTPVERAPYKGEVATLKSRVTKEDATAGTRKQAHP 519 V R Y G V L + T + T + P Sbjct: 490 DLHAVPRGMYDGPVFDLTT--TPKGGTPAGSARGSP 523 >4LCQ-A nrPDB Length = 520 Score = 719 bits (1856), Expect = 0.0, Method: Composition-based stats. Identities = 368/502 (73%), Positives = 429/502 (85%), Gaps = 4/502 (0%) Query: 1 MAAPSRLLIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVL 60 MA +LI+GG+VVN+D S +DV + G + +G DL P GA RV+DA +LV+ Sbjct: 21 MAEAGEILIKGGKVVNEDCSFFSDVHIRGGKIVEVGPDLRVPPGA----RVIDATDRLVI 76 Query: 61 PGGIDTHTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSW 120 PGGIDTHTHM+ FMG+R++DDFH GTKAAL+GGTTMI+DF + QKG SL+EA++ WR Sbjct: 77 PGGIDTHTHMELAFMGTRAVDDFHIGTKAALAGGTTMILDFVMTQKGQSLLEAYDLWRKT 136 Query: 121 ADPKVCCDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEAFS 180 ADPKVCCDYSLHVAVTWWSD+VK+EM+ L Q++GVNSFKMFMAYK L+M+ D ELY FS Sbjct: 137 ADPKVCCDYSLHVAVTWWSDEVKDEMRTLAQERGVNSFKMFMAYKGLFMLRDDELYAVFS 196 Query: 181 RCKEIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAV 240 CKE+GAIAQVHAENGDLIAEGAKKML+LGITGPEGHELCRPEAVEAEAT RAITIASAV Sbjct: 197 HCKEVGAIAQVHAENGDLIAEGAKKMLSLGITGPEGHELCRPEAVEAEATQRAITIASAV 256 Query: 241 NCPLYIVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMGPP 300 NCPLY+VHVMSKSAA V++ AR+DG+VV+GEPIAASLGTDGT+YW+K+W HAA +VMGPP Sbjct: 257 NCPLYVVHVMSKSAADVVSKARKDGRVVFGEPIAASLGTDGTNYWHKDWAHAAQYVMGPP 316 Query: 301 LRPDPSTPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIW 360 LRPDPSTP +LM+LLANDDLT TGTDNCTF+ CQKALGKDDFT+IPNGVNGVEDRMSVIW Sbjct: 317 LRPDPSTPGYLMDLLANDDLTLTGTDNCTFSRCQKALGKDDFTRIPNGVNGVEDRMSVIW 376 Query: 361 EKGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTHH 420 EKGVHSGKMDENRFVAVTS+NAAKIFN YP+KGRIA SDAD+VIWDPK TR ISA+THH Sbjct: 377 EKGVHSGKMDENRFVAVTSSNAAKIFNFYPQKGRIAKDSDADVVIWDPKTTRKISAQTHH 436 Query: 421 QAVNFNIFEGMVCHGVPLVTISRGKVVYEAGVFSVTAGDGKFIPRKPFAEYIYKRIKQRD 480 QAV++NIFEGM CHGVP+VT+SRG+VVYE G V+ G G+FI R+PF+E++YKRI+QRD Sbjct: 437 QAVDYNIFEGMECHGVPVVTVSRGRVVYEEGRLKVSPGQGRFIHRQPFSEFVYKRIRQRD 496 Query: 481 RTCTPTPVERAPYKGEVATLKS 502 P V R PY GEV L + Sbjct: 497 EVGKPAVVIREPYAGEVVALGT 518 >1KCX-A nrPDB Length = 518 Score = 712 bits (1837), Expect = 0.0, Method: Composition-based stats. Identities = 304/516 (58%), Positives = 390/516 (75%), Gaps = 6/516 (1%) Query: 4 PSRLLIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGG 63 RLLIRGGR++NDD S ADV +EDG+++ +G +L+ PGG ++ ++A G++V+PGG Sbjct: 7 SDRLLIRGGRIINDDQSFYADVYLEDGLIKQIGENLIVPGG----VKTIEANGRMVIPGG 62 Query: 64 IDTHTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWADP 123 ID +T++Q P G S DDF QGTKAAL+GGTTMIID +P+ G SL+ +FE W AD Sbjct: 63 IDVNTYLQKPSQGMTSADDFFQGTKAALAGGTTMIIDHVVPEPGSSLLTSFEKWHEAADT 122 Query: 124 KVCCDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEAFSRCK 183 K CCDYSLHV +T W D V+EE+++LVQDKGVNSF+++MAYKDLY ++D +LYEAF+ K Sbjct: 123 KSCCDYSLHVDITSWYDGVREELEVLVQDKGVNSFQVYMAYKDLYQMSDSQLYEAFTFLK 182 Query: 184 EIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAVNCP 243 +GA+ VHAENGDLIA+ K++L +GITGPEGH L RPE +EAEA RAI IA +NCP Sbjct: 183 GLGAVILVHAENGDLIAQEQKRILEMGITGPEGHALSRPEELEAEAVFRAIAIAGRINCP 242 Query: 244 LYIVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMGPPLRP 303 +YI VMSKSAA +IA AR+ G +V+GEPIAASLGTDGTHYW+K W AA V PPL P Sbjct: 243 VYITKVMSKSAADIIALARKKGPLVFGEPIAASLGTDGTHYWSKNWAKAAAFVTSPPLSP 302 Query: 304 DPSTPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIWEKG 363 DP+TPD+L +LLA DL TG+ +C ++T QKA+GKD+FT IP GVNG+E+RM+V+W+K Sbjct: 303 DPTTPDYLTSLLACGDLQVTGSGHCPYSTAQKAVGKDNFTLIPEGVNGIEERMTVVWDKA 362 Query: 364 VHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTHHQAV 423 V +GKMDEN+FVAVTSTNAAKIFNLYPRKGRIAVGSDAD+VIWDP +TI+AK+H V Sbjct: 363 VATGKMDENQFVAVTSTNAAKIFNLYPRKGRIAVGSDADVVIWDPDKMKTITAKSHKSTV 422 Query: 424 NFNIFEGMVCHGVPLVTISRGKVVYEAGVFSVTAGDGKFIPRKPFAEYIYKRIKQRDRTC 483 +NIFEGM CHG PLV IS+GK+V+E G SV+ G G+FIPRKPF E++Y+R++ R + Sbjct: 423 EYNIFEGMECHGSPLVVISQGKIVFEDGNISVSKGMGRFIPRKPFPEHLYQRVRIRSKVF 482 Query: 484 TPTPVERAPYKGEVATLKSRVTKEDATAGTRKQAHP 519 V R Y G V + T + A ++ P Sbjct: 483 GLHSVSRGMYDGPVYEV--PATPKHAAPAPSAKSSP 516 >5NKS-A nrPDB Length = 573 Score = 701 bits (1810), Expect = 0.0, Method: Composition-based stats. Identities = 292/509 (57%), Positives = 363/509 (71%), Gaps = 4/509 (0%) Query: 4 PSRLLIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGG 63 RLLIRGGR+VNDD S ADV VEDG+++ +G +L+ PGG ++ +DA G +VLPGG Sbjct: 15 SDRLLIRGGRIVNDDQSFYADVHVEDGLIKQIGENLIVPGG----IKTIDAHGLMVLPGG 70 Query: 64 IDTHTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWADP 123 +D HT +Q P +G DDF QGTKAAL+GGTTMI+D P G SL+ A+E WR AD Sbjct: 71 VDVHTRLQMPVLGMTPADDFCQGTKAALAGGTTMILDHVFPDTGVSLLAAYEQWRERADS 130 Query: 124 KVCCDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEAFSRCK 183 CCDYSLHV +T W + +KEE++ LV++KGVNSF +FMAYKD +D ++YE FS + Sbjct: 131 AACCDYSLHVDITRWHESIKEELEALVKEKGVNSFLVFMAYKDRCQCSDSQMYEIFSIIR 190 Query: 184 EIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAVNCP 243 ++GA+AQVHAENGD++ E K++L LGITGPEGH L PE VEAEA RA+TIA NCP Sbjct: 191 DLGALAQVHAENGDIVEEEQKRLLELGITGPEGHVLSHPEEVEAEAVYRAVTIAKQANCP 250 Query: 244 LYIVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMGPPLRP 303 LY+ VMSK AA IA A+R G VV+GEPI ASLGTDG+HYW+K W AA V PP+ P Sbjct: 251 LYVTKVMSKGAADAIAQAKRRGVVVFGEPITASLGTDGSHYWSKNWAKAAAFVTSPPVNP 310 Query: 304 DPSTPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIWEKG 363 DP+T D L LL++ DL TG+ +CTF T QKA+GKD+F IP G NG+E+RMS++WEK Sbjct: 311 DPTTADHLTCLLSSGDLQVTGSAHCTFTTAQKAVGKDNFALIPEGTNGIEERMSMVWEKC 370 Query: 364 VHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTHHQAV 423 V SGKMDEN FVAVTSTNAAKIFN YPRKGR+AVGSDAD+VIW+PK T+ ISAKTH+ V Sbjct: 371 VASGKMDENEFVAVTSTNAAKIFNFYPRKGRVAVGSDADLVIWNPKATKIISAKTHNLNV 430 Query: 424 NFNIFEGMVCHGVPLVTISRGKVVYEAGVFSVTAGDGKFIPRKPFAEYIYKRIKQRDRTC 483 +NIFEG+ C G P V IS+G+V E G VT G G+F+PRK F +++YKRIK R+R Sbjct: 431 EYNIFEGVECRGAPAVVISQGRVALEDGKMFVTPGAGRFVPRKTFPDFVYKRIKARNRLA 490 Query: 484 TPTPVERAPYKGEVATLKSRVTKEDATAG 512 V R Y G V + Sbjct: 491 EIHGVPRGLYDGPVHEVMVPAKPGSGAPA 519 >4CNS-A nrPDB Length = 480 Score = 694 bits (1790), Expect = 0.0, Method: Composition-based stats. Identities = 294/481 (61%), Positives = 371/481 (77%), Gaps = 4/481 (0%) Query: 4 PSRLLIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGG 63 RLLI+GGR+VNDD S AD+ +EDG+++ +G +L+ PGG ++ ++A GK+V+PGG Sbjct: 4 SDRLLIKGGRIVNDDQSFYADIYMEDGLIKQIGDNLIVPGG----VKTIEANGKMVIPGG 59 Query: 64 IDTHTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWADP 123 ID HTH Q P+ G ++DDF QGTKAAL+GGTTMIID +P+ SL EA+E WR WAD Sbjct: 60 IDVHTHYQMPYKGMTTVDDFFQGTKAALAGGTTMIIDHVVPEPESSLTEAYEKWREWADG 119 Query: 124 KVCCDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEAFSRCK 183 K CCDY+LHV +T W+D VK+E++ L++DKGVNSF ++MAYKDLY V++ ELYE F+ Sbjct: 120 KSCCDYALHVDITHWNDSVKQEVQNLIKDKGVNSFMVYMAYKDLYQVSNTELYEIFTCLG 179 Query: 184 EIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAVNCP 243 E+GAIAQVHAENGD+IA+ +ML +GITGPEGH L RPE +EAEA RAITIAS NCP Sbjct: 180 ELGAIAQVHAENGDIIAQEQTRMLEMGITGPEGHVLSRPEELEAEAVFRAITIASQTNCP 239 Query: 244 LYIVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMGPPLRP 303 LY+ VMSKSAA +I+ AR+ G VV+GEPI ASLG DGTHYW+K W AA V PPL P Sbjct: 240 LYVTKVMSKSAADLISQARKKGNVVFGEPITASLGIDGTHYWSKNWAKAAAFVTSPPLSP 299 Query: 304 DPSTPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIWEKG 363 DP+TPD++ +LLA+ DL +G+ +CTF+T QKA+GKD+FT IP G NGVE+RMSVIW+K Sbjct: 300 DPTTPDYINSLLASGDLQLSGSAHCTFSTAQKAIGKDNFTAIPEGTNGVEERMSVIWDKA 359 Query: 364 VHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTHHQAV 423 V +GKMDEN+FVAVTSTNAAKIFNLYPRKGRI+VGSD+D+VIWDP + +SAK H A Sbjct: 360 VATGKMDENQFVAVTSTNAAKIFNLYPRKGRISVGSDSDLVIWDPDAVKIVSAKNHQSAA 419 Query: 424 NFNIFEGMVCHGVPLVTISRGKVVYEAGVFSVTAGDGKFIPRKPFAEYIYKRIKQRDRTC 483 +NIFEGM G PLV I +GK++ E G VT G G+FIP PF++Y+YKRIK R + Sbjct: 420 EYNIFEGMELRGAPLVVICQGKIMLEDGNLHVTQGAGRFIPCSPFSDYVYKRIKARRKMA 479 Query: 484 T 484 Sbjct: 480 D 480 >2FTW-A nrPDB Length = 521 Score = 689 bits (1777), Expect = 0.0, Method: Composition-based stats. Identities = 294/496 (59%), Positives = 366/496 (73%), Gaps = 7/496 (1%) Query: 3 APSRLLIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPG 62 +LI+ G VVNDD +DVLVE+G+++ + ++ P G ++V+DA KL+LPG Sbjct: 6 QTGTILIKNGTVVNDDRYFKSDVLVENGIIKEISKNIEPKEG----IKVVDATDKLLLPG 61 Query: 63 GIDTHTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWAD 122 GIDTHTH Q PFMG+ S+DDF GT+AA++GGTT IIDF IP +G SL+EA++ W+ WAD Sbjct: 62 GIDTHTHFQLPFMGTVSVDDFDIGTQAAVAGGTTFIIDFVIPTRGQSLLEAYDQWKKWAD 121 Query: 123 PKVCCDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEAFSRC 182 KV CDYSLHVA+TWWS+QV EM+ILV+++GVNSFK FMAYK+ +MVTD E+Y F RC Sbjct: 122 EKVNCDYSLHVAITWWSEQVSREMEILVKERGVNSFKCFMAYKNSFMVTDQEMYHIFKRC 181 Query: 183 KEIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAVNC 242 KE+GAIAQVHAENGD++ EG KKML +GITGPEGHEL RPEA+EAEAT RAI IA +V Sbjct: 182 KELGAIAQVHAENGDMVFEGQKKMLEMGITGPEGHELSRPEALEAEATNRAIVIADSVCT 241 Query: 243 PLYIVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMGPPLR 302 P+YIVHV S AA VI R++G VYGEPIAA LG DG+H WN +W HAA VMGPP+R Sbjct: 242 PVYIVHVQSIGAADVICKHRKEGVRVYGEPIAAGLGVDGSHMWNHDWRHAAAFVMGPPIR 301 Query: 303 PDPSTPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIWEK 362 PDP T LM+ LA DL GTDNCTF QKA+GKDDFTKIPNGVNGVEDRMS++WE Sbjct: 302 PDPRTKGVLMDYLARGDLDCVGTDNCTFCADQKAMGKDDFTKIPNGVNGVEDRMSIVWEN 361 Query: 363 GVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTHHQA 422 GV++GK+ +FV TS+ A+IFN+YPRKGRI VG D DIVIWDP ++TIS THH A Sbjct: 362 GVNTGKLTWCQFVRATSSERARIFNIYPRKGRIDVGCDGDIVIWDPNQSKTISKDTHHHA 421 Query: 423 VNFNIFEGMVCHGVPLVTISRGKVVYEAGVFSVTAGDGKFIPRKPFAEYIYKRIKQRD-- 480 V+FNIFEG+ G+ + TI G +V+ S G G+F+PR PF ++ I+QRD Sbjct: 422 VDFNIFEGIKVTGIAVTTIVAGNIVWSDNKLSCVKGSGRFVPRPPFGP-VFDGIEQRDKV 480 Query: 481 RTCTPTPVERAPYKGE 496 R V+R PY+ + Sbjct: 481 RNELLRKVDRKPYEDD 496 >4B90-A nrPDB Length = 586 Score = 683 bits (1762), Expect = 0.0, Method: Composition-based stats. Identities = 298/518 (57%), Positives = 381/518 (73%), Gaps = 4/518 (0%) Query: 2 AAPSRLLIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLP 61 +A R+LI+GG+VVNDD + ADV +E+G+++ +G +L+ PGGA +V+DA GKLV+P Sbjct: 27 SASVRILIKGGKVVNDDCTHEADVYIENGIIQQVGRELMIPGGA----KVIDATGKLVIP 82 Query: 62 GGIDTHTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWA 121 GGIDT TH FM + +DDF+ GTKAAL GGTTMII +P K SL++A+E R A Sbjct: 83 GGIDTSTHFHQTFMNATCVDDFYHGTKAALVGGTTMIIGHVLPDKETSLVDAYEKCRGLA 142 Query: 122 DPKVCCDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEAFSR 181 DPKVCCDY+LHV +TWW+ +VK EM+ LV++KGVNSF+MFM YKDLYM+ D ELY+ Sbjct: 143 DPKVCCDYALHVGITWWAPKVKAEMETLVREKGVNSFQMFMTYKDLYMLRDSELYQVLHA 202 Query: 182 CKEIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAVN 241 CK+IGAIA+VHAENG+L+AEGAK+ L LGITGPEG E+ RPE +EAEAT R ITIA+ + Sbjct: 203 CKDIGAIARVHAENGELVAEGAKEALDLGITGPEGIEISRPEELEAEATHRVITIANRTH 262 Query: 242 CPLYIVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMGPPL 301 CP+Y+V+V S SA VIA A+ GKVV E A G HY++++W HAA +V PPL Sbjct: 263 CPIYLVNVSSISAGDVIAAAKMQGKVVLAETTTAHATLTGLHYYHQDWSHAAAYVTVPPL 322 Query: 302 RPDPSTPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIWE 361 R D +T +LM+LLAND L +D+ F T QKA+GK+DFTKIP+GV+GV+DRMSVIWE Sbjct: 323 RLDTNTSTYLMSLLANDTLNIVASDHRPFTTKQKAMGKEDFTKIPHGVSGVQDRMSVIWE 382 Query: 362 KGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTHHQ 421 +GV GKMDENRFVAVTS+NAAK+ NLYPRKGRI G+DAD+V+WDP+ T+TISA T Q Sbjct: 383 RGVVGGKMDENRFVAVTSSNAAKLLNLYPRKGRIIPGADADVVVWDPEATKTISASTQVQ 442 Query: 422 AVNFNIFEGMVCHGVPLVTISRGKVVYEAGVFSVTAGDGKFIPRKPFAEYIYKRIKQRDR 481 +FN++E M CHGVPLVTISRG+VVYE GVF G GKF P + F + +YK++ QR++ Sbjct: 443 GGDFNLYENMRCHGVPLVTISRGRVVYENGVFMCAEGTGKFCPLRSFPDTVYKKLVQREK 502 Query: 482 TCTPTPVERAPYKGEVATLKSRVTKEDATAGTRKQAHP 519 T V+R PY G+VA + KE T P Sbjct: 503 TLKVRGVDRTPYLGDVAVVVHPGKKEMGTPLADTPTRP 540 >4TQT-A nrPDB Length = 497 Score = 655 bits (1690), Expect = 0.0, Method: Composition-based stats. Identities = 224/490 (45%), Positives = 313/490 (63%), Gaps = 11/490 (2%) Query: 8 LIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGIDTH 67 +I+GG V+ D + AD+L+EDG + A+G L G V+DA+G V+PGGID H Sbjct: 17 VIKGGTVITADRTFRADILIEDGKIAAIGDSL-------EGDEVIDASGCYVMPGGIDPH 69 Query: 68 THMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWADPKVCC 127 TH+Q PFMG+ S DDF GT AAL+GGTTM++DF +P G+L++A + W A K Sbjct: 70 THLQMPFMGTYSSDDFDTGTAAALAGGTTMVVDFVLPDSEGNLLDALQEWFQKA-GKART 128 Query: 128 DYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEAFSRCKEIGA 187 DYS H+A+T W+++ EM +V+ +G+N+FK FMAYK MV D E++ +F RC E+GA Sbjct: 129 DYSFHMAITGWNERTFNEMAEVVK-RGINTFKHFMAYKGALMVNDDEMFASFQRCAELGA 187 Query: 188 IAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAVNCPLYIV 247 + VHAENGD++A+ K++A G GPE H RP VE EAT RAI IA PLY+V Sbjct: 188 MPLVHAENGDIVAQLQAKLMAEGNDGPEAHAYSRPPEVEGEATNRAIMIADQAGVPLYVV 247 Query: 248 HVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMGPPLRPDPST 307 HV + + + I AR+ G V+GEP+ L D + Y N++W +AA VM PP R D Sbjct: 248 HVSCEQSHEAIRRARQKGMRVFGEPLIQHLTLDESEYHNRDWDYAARRVMSPPFR-DKLN 306 Query: 308 PDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIWEKGVHSG 367 D L LA L TD+C F T QK G +FTKIPNG G+E+RM V+W +GV +G Sbjct: 307 QDSLWAGLAAGSLQCVATDHCAFTTEQKRYGIGNFTKIPNGTGGLEERMPVLWTRGVRTG 366 Query: 368 KMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTHHQAVNFNI 427 ++ N FVAVTSTN AKI N+YP+KG + G+DAD+VIWDP+ T+ ISAKT H ++++N+ Sbjct: 367 RLTPNEFVAVTSTNIAKILNIYPQKGAVVPGADADLVIWDPETTKKISAKTQHSSIDYNV 426 Query: 428 FEGMVCHGVPLVTISRGKVVYEAGVFSVTAGDGKFIPRKPFAEYIYKRIKQRDRTCTPTP 487 FEG G+P++T+SRG++ ++ G + GDG+FI R+P + + + Q P Sbjct: 427 FEGFELKGLPIMTLSRGRIAFDKGQVTAKPGDGRFIEREPNGA-VNRALSQWKEIVAPRK 485 Query: 488 VERAPYKGEV 497 VER+ + Sbjct: 486 VERSAEHMPI 495 >3DC8-A nrPDB Length = 490 Score = 652 bits (1681), Expect = 0.0, Method: Composition-based stats. Identities = 230/485 (47%), Positives = 307/485 (63%), Gaps = 10/485 (2%) Query: 7 LLIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGIDT 66 +I+GG +V D + ADV VE G + +G +L +G LDA G V+PGGID Sbjct: 3 TVIKGGTIVTADLTYKADVKVEGGRIVEIGPNL-------SGAETLDATGCYVMPGGIDP 55 Query: 67 HTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWADPKVC 126 HTH++ PFMG+ S DDF GT+AAL+GGTTM++DFA+P G SL+EA W + + + Sbjct: 56 HTHLEMPFMGTYSSDDFESGTRAALAGGTTMVVDFALPSPGQSLLEALTMWDNKS-TRAN 114 Query: 127 CDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEAFSRCKEIG 186 CDYS H+A+TWW +QV EM+ +V+DKG+N+FK FMAYK MV D E++ +F RC +G Sbjct: 115 CDYSFHMAITWWGEQVFNEMETIVKDKGINTFKHFMAYKGALMVDDDEMFSSFQRCAALG 174 Query: 187 AIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAVNCPLYI 246 A+ VHAENGD++A+ K+LA G +GPE H RP VE EA RAI IA CP+YI Sbjct: 175 ALPLVHAENGDVVAQLQAKLLAEGNSGPEAHAYSRPAEVEGEAANRAIMIADMAGCPVYI 234 Query: 247 VHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMGPPLRPDPS 306 VH + A + I AR G V+GEP+ L D T Y++K+W HAA VM PP R + Sbjct: 235 VHTSCEQAHEAIRRARAKGMRVFGEPLIQHLTLDETEYFDKDWDHAARRVMSPPFR-NKL 293 Query: 307 TPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIWEKGVHS 366 D L LA+ L TD+C F T QK G DFT+IPNG G+EDRM ++W GV + Sbjct: 294 HQDSLWAGLASGSLQVVATDHCAFTTEQKRFGVGDFTRIPNGTGGLEDRMPMLWTYGVAT 353 Query: 367 GKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTHHQAVNFN 426 G++ N FVAVTSTN AKI N+YP+KG I VG+DAD+V+WDPK ++TISAKT A+++N Sbjct: 354 GRITMNEFVAVTSTNIAKILNIYPKKGAILVGADADLVVWDPKRSKTISAKTQQSAIDYN 413 Query: 427 IFEGMVCHGVPLVTISRGKVVYEAGVFSVTAGDGKFIPRKPFAEYIYKRIKQRDRTCTPT 486 +FEG G+P T++RG V E G G G+F+ R PF + + P Sbjct: 414 VFEGKTVTGLPRFTLTRGVVSIEEGTVKTQEGHGEFVRRDPFPA-VSTALSTWKEVTAPR 472 Query: 487 PVERA 491 V+R+ Sbjct: 473 AVQRS 477 >6AJD-A nrPDB Length = 485 Score = 650 bits (1676), Expect = 0.0, Method: Composition-based stats. Identities = 248/484 (51%), Positives = 322/484 (66%), Gaps = 7/484 (1%) Query: 7 LLIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGIDT 66 LLIRG VV + S ADVL +G+++A+G +L P +G VLD G+ ++PGGID Sbjct: 3 LLIRGATVVTHEESYRADVLCANGLIQAIGENLETP----SGCDVLDGGGQYLMPGGIDP 58 Query: 67 HTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWADPKVC 126 HTHMQ PFMG+ + +DF GT A L+GGTT IIDF IP SL+EAF TWR WA K Sbjct: 59 HTHMQLPFMGTVASEDFFSGTAAGLAGGTTSIIDFVIPNPRQSLLEAFHTWRGWA-QKSA 117 Query: 127 CDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEAFSRCKEIG 186 DY HVA+TWWSD+V EM LV GVNSFK FMAYK+ M D L +F RC E+G Sbjct: 118 ADYGFHVAITWWSDEVAREMGELVAQHGVNSFKHFMAYKNAIMAADDTLVASFERCLELG 177 Query: 187 AIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAVNCPLYI 246 A+ VHAENG+L+ +K+LA G+TGPE H L RP VE EA RAI IA + PLY+ Sbjct: 178 AVPTVHAENGELVFHLQQKLLAQGLTGPEAHPLSRPPQVEGEAASRAIRIAETLGTPLYL 237 Query: 247 VHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMGPPLRPDPS 306 VH+ S+ A IA AR G+ VYGE +A L D + Y + +W AA +VM PP RP Sbjct: 238 VHISSREALDEIAYARAKGQPVYGEVLAGHLLLDDSVYRHPDWATAAGYVMSPPFRPVE- 296 Query: 307 TPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIWEKGVHS 366 + L L + +L TT TD+C F QKA+G+DDF+KIPNG G+EDRM+++W+ GV+S Sbjct: 297 HQEALWRGLQSGNLHTTATDHCCFCAEQKAMGRDDFSKIPNGTAGIEDRMALLWDAGVNS 356 Query: 367 GKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTHHQAVNFN 426 G++ + FVA+TSTN AKIFNL+PRKG I VG+DAD+V+WDP+G+RT+SA THHQ V+FN Sbjct: 357 GRLSMHEFVALTSTNTAKIFNLFPRKGAIRVGADADLVLWDPQGSRTLSAATHHQRVDFN 416 Query: 427 IFEGMVCHGVPLVTISRGKVVYEAGVFSVTAGDGKFIPRKPFAEYIYKRIKQRDRTCTPT 486 IFEG G+P TIS+GK+++ AG G G+++ R P +Y+ + +R P Sbjct: 417 IFEGRTVRGIPSHTISQGKLLWAAGDLRAEPGAGRYVER-PAYPSVYEVLGRRAERQRPV 475 Query: 487 PVER 490 VER Sbjct: 476 AVER 479 >4B91-A nrPDB Length = 484 Score = 645 bits (1663), Expect = 0.0, Method: Composition-based stats. Identities = 287/483 (59%), Positives = 367/483 (75%), Gaps = 4/483 (0%) Query: 2 AAPSRLLIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLP 61 +A R+LI+GG+VVNDD + ADV +E+G+++ +G +L+ PGGA +V+DA GKLV+P Sbjct: 6 SASVRILIKGGKVVNDDCTHEADVYIENGIIQQVGRELMIPGGA----KVIDATGKLVIP 61 Query: 62 GGIDTHTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWA 121 GGIDT TH FM + +DDF+ GTKAAL GGTTMII +P K SL++A+E R A Sbjct: 62 GGIDTSTHFHQTFMNATCVDDFYHGTKAALVGGTTMIIGHVLPDKETSLVDAYEKCRGLA 121 Query: 122 DPKVCCDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEAFSR 181 DPKVCCDY+LHV +TWW+ +VK EM+ LV++KGVNSF+MFM YKDLYM+ D ELY+ Sbjct: 122 DPKVCCDYALHVGITWWAPKVKAEMETLVREKGVNSFQMFMTYKDLYMLRDSELYQVLHA 181 Query: 182 CKEIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAVN 241 CK+IGAIA+VHAENG+L+AEGAK+ L LGITGPEG E+ RPE +EAEAT R ITIA+ + Sbjct: 182 CKDIGAIARVHAENGELVAEGAKEALDLGITGPEGIEISRPEELEAEATHRVITIANRTH 241 Query: 242 CPLYIVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMGPPL 301 CP+Y+V+V S SA VIA A+ GKVV E A G HY++++W HAA +V PPL Sbjct: 242 CPIYLVNVSSISAGDVIAAAKMQGKVVLAETTTAHATLTGLHYYHQDWSHAAAYVTVPPL 301 Query: 302 RPDPSTPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIWE 361 R D +T +LM+LLAND L +D+ F T QKA+GK+DFTKIP+GV+GV+DRMSVIWE Sbjct: 302 RLDTNTSTYLMSLLANDTLNIVASDHRPFTTKQKAMGKEDFTKIPHGVSGVQDRMSVIWE 361 Query: 362 KGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTHHQ 421 +GV GKMDENRFVAVTS+NAAK+ NLYPRKGRI G+DAD+V+WDP+ T+TISA T Q Sbjct: 362 RGVVGGKMDENRFVAVTSSNAAKLLNLYPRKGRIIPGADADVVVWDPEATKTISASTQVQ 421 Query: 422 AVNFNIFEGMVCHGVPLVTISRGKVVYEAGVFSVTAGDGKFIPRKPFAEYIYKRIKQRDR 481 +FN++E M CHGVPLVTISRG+VVYE GVF G GKF P + F + +YK++ QR++ Sbjct: 422 GGDFNLYENMRCHGVPLVTISRGRVVYENGVFMCAEGTGKFCPLRSFPDTVYKKLVQREK 481 Query: 482 TCT 484 T Sbjct: 482 TLK 484 >1YNY-A nrPDB Length = 461 Score = 623 bits (1606), Expect = e-179, Method: Composition-based stats. Identities = 204/463 (44%), Positives = 276/463 (59%), Gaps = 8/463 (1%) Query: 9 IRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGIDTHT 68 IRGG VV + ADVL+E V A+GH L G +DA G V+PGGID HT Sbjct: 5 IRGGTVVTAADTYQADVLIEGERVVAIGHQLSVNGA-----EEIDATGCYVIPGGIDPHT 59 Query: 69 HMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWADPKVCCD 128 H+ PF G+ + DDF GT+AA GGTT I+DF + +KG SL A TW A K D Sbjct: 60 HLDMPFGGTVTADDFFTGTRAAAFGGTTSIVDFCLTKKGESLKSAIATWHEKARGKAVID 119 Query: 129 YSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEAFSRCKEIGAI 188 Y H+ + +DQV EE++ ++ +G+ S K+FMAYK+++ D L++ + KE+GA+ Sbjct: 120 YGFHLMIAEANDQVLEELESVISSEGITSLKVFMAYKNVFQADDETLFKTLVKAKELGAL 179 Query: 189 AQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAVNCPLYIVH 248 QVHAENGD++ KK LA G T P H RP E EAT RAI + + LY+VH Sbjct: 180 VQVHAENGDVLDYLTKKALAEGNTDPIYHAYTRPPEAEGEATGRAIALTALAGSQLYVVH 239 Query: 249 VMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMGPPLRPDPSTP 308 V SA + IA+AR G VYGE L D ++ A +V PPLR + Sbjct: 240 VSCASAVQRIAEAREKGWNVYGETCPQYLALD-VSIMDQPDFEGAKYVWSPPLR-EKWNQ 297 Query: 309 DFLMNLLANDDLTTTGTDNCTFN-TCQKALGKDDFTKIPNGVNGVEDRMSVIWEKGVHSG 367 + L + L N L T G+D+C FN QK LG+ DFTKIPNG +EDR+++++ +GV G Sbjct: 298 EVLWSALKNGILQTVGSDHCPFNFRGQKELGRGDFTKIPNGGPLIEDRLTILYSEGVRQG 357 Query: 368 KMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTHHQAVNFNI 427 ++ N+FV ++ST AAK+F ++PRKG IAVGSDADIVI+DP RT+S +THH V++N Sbjct: 358 RISLNQFVDISSTKAAKLFGMFPRKGTIAVGSDADIVIFDPHVKRTLSVETHHMNVDYNP 417 Query: 428 FEGMVCHGVPLVTISRGKVVYEAGVFSVTAGDGKFIPRKPFAE 470 FEGM +G + +SRG V F AG G++I R F + Sbjct: 418 FEGMEVYGEVVSVLSRGSFVVRDKQFVGQAGSGQYIKRTTFEQ 460 >1K1D-A nrPDB Length = 460 Score = 621 bits (1602), Expect = e-178, Method: Composition-based stats. Identities = 195/463 (42%), Positives = 270/463 (58%), Gaps = 8/463 (1%) Query: 8 LIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGIDTH 67 +I+ G +V + A +L++DG + +G +L G V+DA G V PGGID H Sbjct: 4 IIKNGTIVTATDTYEAHLLIKDGKIAMIGQNLEEKGA-----EVIDAKGCYVFPGGIDPH 58 Query: 68 THMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWADPKVCC 127 TH+ P G+ + DDF GT AA GGTT IIDF + KG L +A ETW + A+ K Sbjct: 59 THLDMPLGGTVTKDDFESGTIAAAFGGTTTIIDFCLTNKGEPLKKAIETWHNKANGKAVI 118 Query: 128 DYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEAFSRCKEIGA 187 DY H+ ++ +D V EE+ +++++G+ S K+FMAYK+++ D LY KE+GA Sbjct: 119 DYGFHLMISEITDDVLEELPKVLEEEGITSLKVFMAYKNVFQADDGTLYCTLLAAKELGA 178 Query: 188 IAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAVNCPLYIV 247 + VHAENGD+I KK LA G T P H L RP +E EAT RA + LY+V Sbjct: 179 LVMVHAENGDVIDYLTKKALADGNTDPIYHALTRPPELEGEATGRACQLTELAGSQLYVV 238 Query: 248 HVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMGPPLRPDPST 307 HV A + IA+AR G V+GE L D + Y K A +V PPLR + Sbjct: 239 HVTCAQAVEKIAEARNKGLDVWGETCPQYLVLDQS-YLEKPNFEGAKYVWSPPLR-EKWH 296 Query: 308 PDFLMNLLANDDLTTTGTDNCTFN-TCQKALGKDDFTKIPNGVNGVEDRMSVIWEKGVHS 366 + L N L N L T G+D C+F+ QK LG+ DFTKIPNG +EDR+S+++ +GV Sbjct: 297 QEVLWNALKNGQLQTLGSDQCSFDFKGQKELGRGDFTKIPNGGPIIEDRVSILFSEGVKK 356 Query: 367 GKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTHHQAVNFN 426 G++ N+FV + ST AK+F L+P+KG I VGSDAD+VI+DP R ISA+THH AV++N Sbjct: 357 GRITLNQFVDIVSTRIAKLFGLFPKKGTIVVGSDADLVIFDPNIERVISAETHHMAVDYN 416 Query: 427 IFEGMVCHGVPLVTISRGKVVYEAGVFSVTAGDGKFIPRKPFA 469 FEGM G P+ + RG+ V F G G+++ R + Sbjct: 417 AFEGMKVTGEPVSVLCRGEFVVRDKQFVGKPGYGQYLKRAKYG 459 >3SFW-A nrPDB Length = 461 Score = 621 bits (1601), Expect = e-178, Method: Composition-based stats. Identities = 208/462 (45%), Positives = 275/462 (59%), Gaps = 8/462 (1%) Query: 9 IRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGIDTHT 68 IR G VV + ADVL++ V A+G DL V+DA G +LPGGID HT Sbjct: 5 IRNGTVVTASDTYQADVLIDGEKVVAIGSDLQATDA-----EVIDATGYYLLPGGIDPHT 59 Query: 69 HMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWADPKVCCD 128 H+ PF G+ + D+F GTKAA GGTT I+DF + KG SL A TW A K D Sbjct: 60 HLDMPFGGTVTSDNFFTGTKAAAFGGTTSIVDFCLTSKGESLHSAIATWHEKARGKAVID 119 Query: 129 YSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEAFSRCKEIGAI 188 Y H+ V+ +D V EE++ +V ++G+ S K+FMAYK++ M D L++ R KE+GA+ Sbjct: 120 YGFHLMVSDANDHVLEELESVVNNEGITSLKVFMAYKNVLMADDETLFKTLIRAKELGAL 179 Query: 189 AQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAVNCPLYIVH 248 QVHAENGD++ K+ LA G T P H RP E EAT RAI + + + LY+VH Sbjct: 180 VQVHAENGDVLDYLTKQALAEGNTDPIYHAYTRPPEAEGEATGRAIALTALADAQLYVVH 239 Query: 249 VMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMGPPLRPDPSTP 308 V A + IA+AR G VYGE L D T K A +V PPLR + Sbjct: 240 VSCADAVRRIAEAREKGWNVYGETCPQYLVLDITA-LEKPDFEGAKYVWSPPLR-EKWNQ 297 Query: 309 DFLMNLLANDDLTTTGTDNCTFN-TCQKALGKDDFTKIPNGVNGVEDRMSVIWEKGVHSG 367 D L + L N L T G+D+C FN + QK LG+ DFTKIPNG +EDRM++++ +GV G Sbjct: 298 DVLWSALKNGILQTVGSDHCPFNFSGQKELGRRDFTKIPNGGPIIEDRMTILFSEGVRKG 357 Query: 368 KMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTHHQAVNFNI 427 K+ N+FV +TST AK+F ++P+KG IAVGSDADIV++DP RTIS +THH V++N Sbjct: 358 KISLNQFVDITSTKVAKLFGMFPQKGTIAVGSDADIVLFDPTVQRTISVETHHMNVDYNP 417 Query: 428 FEGMVCHGVPLVTISRGKVVYEAGVFSVTAGDGKFIPRKPFA 469 FEGM HG + +SRG V F AG G+++ R FA Sbjct: 418 FEGMQVHGDVISVLSRGAFVVRNKQFVGHAGAGRYVKRSTFA 459 >1GKQ-A nrPDB Length = 458 Score = 566 bits (1458), Expect = e-161, Method: Composition-based stats. Identities = 187/461 (40%), Positives = 265/461 (57%), Gaps = 7/461 (1%) Query: 7 LLIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGIDT 66 LLI+ G ++ D AD+ E + +G +L AP G V+DA GK V PG ID Sbjct: 2 LLIKNGEIITADSRYKADIYAEGETITRIGQNL----EAPPGTEVIDATGKYVFPGFIDP 57 Query: 67 HTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWADPKVC 126 H H+ PFM + + D G+KAAL GGTT I+ P + +E ++ W+S A+ Sbjct: 58 HVHIYLPFMATFAKDTHETGSKAALMGGTTTYIEMCCPSRNDDALEGYQLWKSKAEGNSY 117 Query: 127 CDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEAFSRCKEIG 186 CDY+ H+AV+ + ++ + +++ +V D G++SFK+F++YK+ + V D E+Y+ KE+G Sbjct: 118 CDYTFHMAVSKFDEKTEGQLREIVAD-GISSFKIFLSYKNFFGVDDGEMYQTLRLAKELG 176 Query: 187 AIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAVNCPLYI 246 I H EN +L+ +K+L+ G TGPE HE RPEAVEAE T R T Y+ Sbjct: 177 VIVTAHCENAELVGRLQQKLLSEGKTGPEWHEPSRPEAVEAEGTARFATFLETTGATGYV 236 Query: 247 VHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMGPPLRPDPS 306 VH+ K A A+ G +Y E + D T Y + A ++M PPLR D Sbjct: 237 VHLSCKPALDAAMAAKARGVPIYIESVIPHFLLDKT-YAERGGVEAMKYIMSPPLR-DKR 294 Query: 307 TPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIWEKGVHS 366 L + LA + T GTD+C F+T QK LGK+ FT IPNG+ +EDR+++++ GV Sbjct: 295 NQKVLWDALAQGFIDTVGTDHCPFDTEQKLLGKEAFTAIPNGIPAIEDRVNLLYTYGVSR 354 Query: 367 GKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTHHQAVNFN 426 G++D +RFV ST AAK+F L+PRKG IAVGSDAD+V++DP+ TIS KT H ++N Sbjct: 355 GRLDIHRFVDAASTKAAKLFGLFPRKGTIAVGSDADLVVYDPQYRGTISVKTQHVNNDYN 414 Query: 427 IFEGMVCHGVPLVTISRGKVVYEAGVFSVTAGDGKFIPRKP 467 FEG G P V RGKV G F G GK + R+P Sbjct: 415 GFEGFEIDGRPSVVTVRGKVAVRDGQFVGEKGWGKLLRREP 455 >1NFG-A nrPDB Length = 457 Score = 530 bits (1364), Expect = e-151, Method: Composition-based stats. Identities = 173/465 (37%), Positives = 253/465 (54%), Gaps = 11/465 (2%) Query: 7 LLIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGIDT 66 ++I+ G +V D AD+ ++DG + +G L P R +DAAG+ V PGGID Sbjct: 3 IIIKNGTIVTADGISRADLGIKDGKITQIGGALGP------AERTIDAAGRYVFPGGIDV 56 Query: 67 HTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWADPKVC 126 HTH++ ++S D F T AA GGTT I+DF +G SL EA W A K Sbjct: 57 HTHVETVSFNTQSADTFATATVAAACGGTTTIVDFCQQDRGHSLAEAVAKWDGMAGGKSA 116 Query: 127 CDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEAFSRCKEIG 186 DY H+ V +D V EE+++L D G+ SFK+FMAY+ + M+ D+ L + + + G Sbjct: 117 IDYGYHIIVLDPTDSVIEELEVL-PDLGITSFKVFMAYRGMNMIDDVTLLKTLDKAVKTG 175 Query: 187 AIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAVNCPLYI 246 ++ VHAENGD K +A G T P H L RP VEAEAT RA+ +A VN P+YI Sbjct: 176 SLVMVHAENGDAADYLRDKFVAEGKTAPIYHALSRPPRVEAEATARALALAEIVNAPIYI 235 Query: 247 VHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMGPPLRPDPS 306 VHV + + + + A+ G E L + A +V PP R Sbjct: 236 VHVTCEESLEEVMRAKSRGVRALAETCTHYLYLTK-EDLERPDFEGAKYVFTPPARAKKD 294 Query: 307 TPDFLMNLLANDDLTTTGTDNCT-FNTCQKALGKDDFTKIPNGVNGVEDRMSVIWEKGVH 365 D L N L N T +D+C+ K G++DF IPNG GVE+R+ ++++ GV+ Sbjct: 295 H-DVLWNALRNGVFETVSSDHCSWLFKGHKDRGRNDFRAIPNGAPGVEERLMMVYQ-GVN 352 Query: 366 SGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTHHQAVNF 425 G++ +FV + +T AK+F ++P+KG IAVGSDADIV+WDP+ I H A+++ Sbjct: 353 EGRISLTQFVELVATRPAKVFGMFPQKGTIAVGSDADIVLWDPEAEMVIEQTAMHNAMDY 412 Query: 426 NIFEGMVCHGVPLVTISRGKVVYEAGVFSVTAGDGKFIPRKPFAE 470 + +EG GVP + RGKV+ + G + DGKF+ R+ + + Sbjct: 413 SSYEGHKVKGVPKTVLLRGKVIVDEGSYVGEPTDGKFLKRRKYKQ 457 >2FTY-A nrPDB Length = 559 Score = 481 bits (1237), Expect = e-136, Method: Composition-based stats. Identities = 150/521 (28%), Positives = 247/521 (47%), Gaps = 68/521 (13%) Query: 7 LLIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGIDT 66 L+I+ G + A++ V +G V+ + + P G+ V+DA G + PGGID Sbjct: 5 LIIKNGIICTASDIYAAEIAVNNGKVQLIAASIDPSLGS----EVIDAEGAFITPGGIDA 60 Query: 67 HTHMQFPF-MGSRSIDDFHQGTKAALSGGTTMIIDFA---IPQKGGS-LIEAFET-WRSW 120 H H+ P + +D T++A++GGTT ++ F+ + +KG S L E+ + + Sbjct: 61 HVHVDEPLKLLGDVVDTMEHATRSAVAGGTTTVVAFSTQDVSKKGPSALAESVKLDVDEY 120 Query: 121 ADPKVCCDYSLHV---AVTWWSDQVKEEMKILVQ----DKGVNSFKMFMAYKDLYMVTDL 173 ++ + CDY LH+ + S + +E + + +Q D GV+S KMFM Y L ++D Sbjct: 121 SEQTLYCDYGLHLILFQIEKPSVEARELLDVQLQAAYNDYGVSSVKMFMTYPGL-QISDY 179 Query: 174 ELYEAFSRCKEIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRA 233 ++ A ++ G +HAENGD++ + + G+T H + RP VE EAT RA Sbjct: 180 DIMSAMYATRKNGFTTMLHAENGDMVKWMIEALEEQGLTDAYYHGVSRPSIVEGEATNRA 239 Query: 234 ITIASAVNCPLYIVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDG------------ 281 IT+A+ ++ P+ VHV S AA+VI A+ G VY E Sbjct: 240 ITLATTMDTPILFVHVSSPQAAEVIKQAQTKGLKVYAETCPQYALLSDAITRCHHHGEVE 299 Query: 282 -------------THYWNKEW-HHAAHHVMGPPLRPDPSTPDFLMNLLANDDLTTTGTDN 327 + + N + + ++ PP+RP T + + N T G+D+ Sbjct: 300 SYGVGIDLSSISESPFTNPDDRFIGSKYICSPPIRP-EGTQKSIWKGMNNGTFTIVGSDH 358 Query: 328 CTFNTCQKALGK-------------DDFTKIPNGVNGVEDRMSVIWEKGVHSGKMD-ENR 373 C++N +K +F IPNG+ GV RM ++++ G G + + Sbjct: 359 CSYNYYEKTSTASKHRAFDPENNKNGEFRYIPNGLPGVCTRMPLLYDYGYLRGNLTSMMK 418 Query: 374 FVAVTSTNAAKIFNLYPRKGRIAVG-SDADIVIWDPKGTRT--------ISAKTHHQAVN 424 V + TN AK++ +YP+KG I G SDAD+VIW P ++ I+ K + Sbjct: 419 LVEIQCTNPAKVYGMYPQKGSILPGVSDADLVIWYPDDSKKEYNSKPKLITNKLMEHNCD 478 Query: 425 FNIFEGMVCHGVPLVTISRGKVVYEAGVFSVTAGDGKFIPR 465 + FEG+ P TI +GK+VY+ G DGK++ R Sbjct: 479 YTPFEGIEIKNWPRYTIVKGKIVYKEGEILKENADGKYLKR 519 >1GKR-A nrPDB Length = 458 Score = 464 bits (1195), Expect = e-131, Method: Composition-based stats. Identities = 134/470 (28%), Positives = 220/470 (46%), Gaps = 21/470 (4%) Query: 7 LLIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGIDT 66 ++++ R+V+ D AD+LV+DG V A+ D + R +DA GK V+PG +D Sbjct: 4 VIVKNCRLVSSDGITEADILVKDGKVAAISADTSDVEAS----RTIDAGGKFVMPGVVDE 59 Query: 67 HTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWADPKVC 126 H H+ + +R F +++A GG T II+ I + ++AF + A ++ Sbjct: 60 HVHIIDMDLKNRY-GRFELDSESAAVGGITTIIEMPITFPPTTTLDAFLEKKKQAGQRLK 118 Query: 127 CDYSLHVA-VTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYM---VTDLELYEAFSRC 182 D++L+ V ++++ + D G FK MA M V+D EL+E F Sbjct: 119 VDFALYGGGVPGNLPEIRK-----MHDAGAVGFKSMMAASVPGMFDAVSDGELFEIFQEI 173 Query: 183 KEIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAVNC 242 G++ VHAEN +I K++ A G +E +P E EA RA+ + C Sbjct: 174 AACGSVIVVHAENETIIQALQKQIKAAGGKDMAAYEASQPVFQENEAIQRALLLQKEAGC 233 Query: 243 PLYIVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHV-MGPPL 301 L ++HV + ++I A+ +G+ V+ E L + ++ + PP+ Sbjct: 234 RLIVLHVSNPDGVELIHQAQSEGQDVHCESGPQYLNITTD-----DAERIGPYMKVAPPV 288 Query: 302 RPDPSTPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIWE 361 R L L N + T G+D+ K G D K NG G+E + ++ Sbjct: 289 RSAEMNIR-LWEQLENGLIDTLGSDHGGHPVEDKEPGWKDVWKAGNGALGLETSLPMMLT 347 Query: 362 KGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTHHQ 421 GV+ G++ R V V AK+F +YP+KG + VGSDAD++I D + A Sbjct: 348 NGVNKGRLSLERLVEVMCEKPAKLFGIYPQKGTLQVGSDADLLILDLDIDTKVDASQFRS 407 Query: 422 AVNFNIFEGMVCHGVPLVTISRGKVVYEAGVFSVTAGDGKFIPRKPFAEY 471 ++ F+GM G P++T+ RG VV E G V G G+F+ R+ + Sbjct: 408 LHKYSPFDGMPVTGAPVLTMVRGTVVAEKGEVLVEQGFGQFVTRRNYEAS 457 >3E74-A nrPDB Length = 473 Score = 455 bits (1171), Expect = e-128, Method: Composition-based stats. Identities = 124/466 (26%), Positives = 203/466 (43%), Gaps = 31/466 (6%) Query: 7 LLIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGIDT 66 L+I+ G V+ ++ + V D+ V+ G + A+G DL V+DA+G +V PG +D Sbjct: 25 LIIKNGTVILENEARVVDIAVKGGKIAAIGQDLGD------AKEVMDASGLVVSPGMVDA 78 Query: 67 HTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEA-FETWRSWADPKV 125 HTH+ P G + + GT+AA GG T +I+ + Q ++ A E A K+ Sbjct: 79 HTHISEP--GRSHWEGYETGTRAAAKGGITTMIEMPLNQLPATVDRASIELKFDAAKGKL 136 Query: 126 CCDYS-LHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAY-------KDLYMVTDLELYE 177 D + L V++ D++ E + + GV FK F+A D V D + ++ Sbjct: 137 TIDAAQLGGLVSYNIDRLHE-----LDEVGVVGFKCFVATCGDRGIDNDFRDVNDWQFFK 191 Query: 178 AFSRCKEIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIA 237 + E+G VH EN + E ++ G + RP E EA R + +A Sbjct: 192 GAQKLGELGQPVLVHCENALICDELGEEAKREGRVTAHDYVASRPVFTEVEAIRRVLYLA 251 Query: 238 SAVNCPLYIVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVM 297 C L++ HV S + + AR++G+ + E D + +E A Sbjct: 252 KVAGCRLHVCHVSSPEGVEEVTRARQEGQDITCESCPHYFVLDTDQF--EEIGTLAK--C 307 Query: 298 GPPLRPDPSTPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMS 357 PP+R D + L N ++ +D+ C + + K G+ G++ M Sbjct: 308 SPPIR-DLENQKGMWEKLFNGEIDCLVSDHSP---CPPEMKAGNIMKAWGGIAGLQSCMD 363 Query: 358 VIWEKGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAK 417 V++++ V M F + +TNAA IF L +KGRIA G DAD V P + ++ Sbjct: 364 VMFDEAVQKRGMSLPMFGKLMATNAADIFGLQ-QKGRIAPGKDADFVFIQPNSSYVLTND 422 Query: 418 THHQAVNFNIFEGMVCHGVPLVTISRGKVVYEAGVFSVTAGDGKFI 463 + + G TI RG V+Y+ A G+FI Sbjct: 423 DLEYRHKVSPYVGRTIGARITKTILRGDVIYDIEQGFPVAPKGQFI 468 >3HM7-A nrPDB Length = 448 Score = 438 bits (1127), Expect = e-123, Method: Composition-based stats. Identities = 119/452 (26%), Positives = 189/452 (41%), Gaps = 24/452 (5%) Query: 7 LLIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGIDT 66 L+IR VV + + ADV + +G+V A+ +D G + PG +D Sbjct: 8 LIIRSSTVVTETTTYRADVAIRNGIVSAITEPGSISSDDGPA---IDGTGLHLFPGMVDV 64 Query: 67 HTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLI-EAFETWRSWADPKV 125 H H P G + F G+K+ +GG T D + ++ E + R A+ K Sbjct: 65 HVHFNEP--GRTEWEGFASGSKSLAAGGVTTYFDMPLNSNPPTITREELDKKRQLANEKS 122 Query: 126 CCDYSLHVAVTWWSDQVKEEMKIL--VQDKGVNSFKMFMA---YKDLYMVTDLELYEAFS 180 DY W V + L + D GV FK FM+ D D L + Sbjct: 123 LVDYRF------WGGLVPGNIDHLQDLHDGGVIGFKAFMSECGTDDFQFSHDETLLKGMK 176 Query: 181 RCKEIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAV 240 + +G+I VHAE+ +++ + + + RP E EA R + A Sbjct: 177 KIAALGSILAVHAESNEMVNALTTIAIEEQRLTVKDYSEARPIVSELEAVERILRFAQLT 236 Query: 241 NCPLYIVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMGPP 300 CP++I HV S+ K I A+ +G V E L + E + A PP Sbjct: 237 CCPIHICHVSSRKVLKRIKQAKGEGVNVSVETCPHYLLFSLDEFA--EIGYLAK--CAPP 292 Query: 301 LRPDPSTPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIW 360 LR D L + L ++ +D+ + Q GK F ++ G+ G ++ ++V+ Sbjct: 293 LRERQEVED-LWDGLMAGEIDLISSDHSP-SLPQMKTGKTIF-EVWGGIAGCQNTLAVML 349 Query: 361 EKGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTHH 420 +G H KM + V + ST AK F LYP+KG I VG++A + D + T++A + Sbjct: 350 TEGYHKRKMPLTQIVQLLSTEPAKRFGLYPQKGTIQVGAEASFTLIDLNESYTLNASDLY 409 Query: 421 QAVNFNIFEGMVCHGVPLVTISRGKVVYEAGV 452 + + G G TI +GK VY+ Sbjct: 410 YRHPISPYVGQRFRGKVKHTICQGKHVYQDHE 441 >3MPG-A nrPDB Length = 428 Score = 423 bits (1087), Expect = e-118, Method: Composition-based stats. Identities = 113/456 (24%), Positives = 177/456 (38%), Gaps = 39/456 (8%) Query: 8 LIRGGRVVNDDFSEVA-DVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGIDT 66 L + GR +N++ VA D+LV+DG + + ++ V+D GKL+ PG +D Sbjct: 4 LFKNGRYMNEEGKIVATDLLVQDGKIAKVAENITADNA-----EVIDVNGKLIAPGLVDV 58 Query: 67 HTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWADPKVC 126 H H++ P G + GT AA GG T I + E E ++ K Sbjct: 59 HVHLREP--GGEHKETIETGTLAAAKGGFTTICAMPNTRPVPDCREHMEDLQNRIKEKAH 116 Query: 127 CDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTD-LELYEAFSRCKEI 185 + + A+T V++ + + + F D V D + A R ++ Sbjct: 117 VNVLPYGAIT-----VRQAGSEMTDFETLKELGAFAFTDDGVGVQDASMMLAAMKRAAKL 171 Query: 186 GAIAQVHAENGDLIAEGA----KKMLALGITGPEGHELCRPEAVEAEATLRAITIASAVN 241 H E LI +G K G+ G P E+ R I +A A + Sbjct: 172 NMAVVAHCEENTLINKGCVHEGKFSEKHGLNGI-------PSVCESVHIARDILLAEAAD 224 Query: 242 CPLYIVHVMSKSAAKVIADARRDGKVVYGE--PIAASLGTDGTHYWNKEWHHAAHHVMGP 299 C ++ HV +K + +VI DA+R G V E P L D + + M P Sbjct: 225 CHYHVCHVSTKGSVRVIRDAKRAGIKVTAEVTPHHLVLCEDDIPSADPNFK------MNP 278 Query: 300 PLRPDPSTPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVI 359 PLR + LL + + TD+ +KA G + P G+ G E ++ Sbjct: 279 PLRGKEDHEALIEGLL-DGTIDMIATDHAPHTAEEKAQG---IERAPFGITGFETAFPLL 334 Query: 360 WEKGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTH 419 + V G + + + + A F L GR+ G ADI I D + I T Sbjct: 335 YTNLVKKGIITLEQLIQFLTEKPADTFGL--EAGRLKEGRTADITIIDLEQEEEIDPTTF 392 Query: 420 HQAVNFNIFEGMVCHGVPLVTISRGKVVYEAGVFSV 455 F G C G P++TI GK+ ++ V Sbjct: 393 LSKGKNTPFAGWKCQGWPVMTIVGGKIAWQKESALV 428 >3GRI-A nrPDB Length = 424 Score = 419 bits (1076), Expect = e-117, Method: Composition-based stats. Identities = 113/449 (25%), Positives = 182/449 (40%), Gaps = 37/449 (8%) Query: 8 LIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGIDTH 67 LI+ G+V+ + + AD+L++ V++ + + P G + ++DA G V PG +D H Sbjct: 3 LIKNGKVLQNGELQQADILIDGKVIKQIAPAIEPSNG----VDIIDAKGHFVSPGFVDVH 58 Query: 68 THMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWADPKVCC 127 H++ P G + GTKAA GG T + + +E FE + D Sbjct: 59 VHLREP--GGEYKETIETGTKAAARGGFTTVCPMPNTRPVPDSVEHFEALQKLID----- 111 Query: 128 DYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKD-LYMVTDLELYEAFSRCKEIG 186 D + + + S ++ K LV + F D + + T +YE ++ Sbjct: 112 DNAQVRVLPYASITTRQLGKELVDFPALVKEGAFAFTDDGVGVQTASMMYEGMIEAAKVN 171 Query: 187 AIAQVHAENGDLIAEGA----KKMLALGITGPEGHELCRPEAVEAEATLRAITIASAVNC 242 H E+ LI GA K+ LGI G P E+ R + +A A C Sbjct: 172 KAIVAHCEDNSLIYGGAMHEGKRSKELGIPGI-------PNICESVQIARDVLLAEAAGC 224 Query: 243 PLYIVHVMSKSAAKVIADARRDGKVVYGE--PIAASLGTDGTHYWNKEWHHAAHHVMGPP 300 ++ HV +K + +VI DA+R G V E P L D N A + M PP Sbjct: 225 HYHVCHVSTKESVRVIRDAKRAGIHVTAEVTPHHLLLTEDDIPGNN------AIYKMNPP 278 Query: 301 LRPDPSTPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIW 360 LR L LL + + TD+ +KA K P G+ G E +++ Sbjct: 279 LRSTEDREALLEGLL-DGTIDCIATDHAPHARDEKA---QPMEKAPFGIVGSETAFPLLY 334 Query: 361 EKGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTHH 420 V +G + V + + FNL G + AD+ I D + I + Sbjct: 335 THFVKNGDWTLQQLVDYLTIKPCETFNL--EYGTLKENGYADLTIIDLDSEQEIKGEDFL 392 Query: 421 QAVNFNIFEGMVCHGVPLVTISRGKVVYE 449 + F G +G P++T+ G+V +E Sbjct: 393 SKADNTPFIGYKVYGNPILTMVEGEVKFE 421 >2GWN-A nrPDB Length = 452 Score = 411 bits (1057), Expect = e-115, Method: Composition-based stats. Identities = 85/456 (18%), Positives = 167/456 (36%), Gaps = 22/456 (4%) Query: 2 AAPSRLLIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLP 61 + ++L+R + N+ + V+++ + + LP + V++ +G + P Sbjct: 1 SNAMKILLRNALITNEGKTFPGSVMIDGAFISRIIEGELPADDNLSADEVIECSGLRLFP 60 Query: 62 GGIDTHTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWA 121 G ID H + P G ++AA++GG T +D ++ E R Sbjct: 61 GCIDDQVHFREP--GLTHKATIASESRAAVAGGVTSFMDMPNTNPPTTMWERLLEKRQIG 118 Query: 122 DPKVCCDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDL--ELYEAF 179 +Y T +D + E + V V K+F+ M+ D L + F Sbjct: 119 ADTAWANYGFFFGGT--NDNIDEIKR--VDKHLVPGLKLFLGSSTGNMLVDNKETLEKIF 174 Query: 180 SRCKEIGAIAQVHAENGDLIAEGAKKMLAL-GIT-GPEGHELCRPEAVEAEATLRAITIA 237 C + H E ++I + A G H L R E ++ A+ +A Sbjct: 175 GECDLL---IATHCEKEEIIRANKEHYKAKYGNDLDIHFHPLIRSEEACYRSSAEAVELA 231 Query: 238 SAVNCPLYIVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVM 297 +N L+I+H+ ++ + R+ + I + + + + ++ + + Sbjct: 232 ERMNARLHILHLSTEKELSLF----RNDIPTAQKRITSEVCVHHLWFSDTDYGRLGNRIK 287 Query: 298 GPPLRPDPSTPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMS 357 P S + L + N + TD+ +K + +G V+ + Sbjct: 288 WNPAIKKESDREALRAAVRNGRIDIIATDHAPHLLREKE---GSCLQAASGGPLVQHSLL 344 Query: 358 VIWEKGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAK 417 + + + G V+ T+ A +F + ++G I G AD+V+ DP T+SA Sbjct: 345 ALL-ELCNQGIFSIEEIVSKTAHIPATLFAI-EKRGYIRPGYYADLVLVDPSSPHTVSAD 402 Query: 418 THHQAVNFNIFEGMVCHGVPLVTISRGKVVYEAGVF 453 ++ FEG T G + Y G Sbjct: 403 NILSLCGWSPFEGFTFSHSVAYTFVNGCLAYAKGRL 438 >1XRT-A nrPDB Length = 467 Score = 369 bits (947), Expect = e-102, Method: Composition-based stats. Identities = 94/457 (20%), Positives = 173/457 (37%), Gaps = 49/457 (10%) Query: 6 RLLIRGGRVVN--DDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGG 63 +L+++ G V++ + D+LVE+G ++ + ++L P ++DA G +V PG Sbjct: 48 KLIVKNGYVIDPSQNLEGEFDILVENGKIKKIDKNILVPEA-----EIIDAKGLIVCPGF 102 Query: 64 IDTHTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWADP 123 ID H H++ P G +D G++ A++GG T I+ D Sbjct: 103 IDIHVHLRDP--GQTYKEDIESGSRCAVAGGFTTIVCMPNTNPP-------------IDN 147 Query: 124 KVCCDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLE--------- 174 +Y L + + +V I KG F + K+ V + Sbjct: 148 TTVVNYILQKSKSVGLCRVLPTGTITKGRKG-KEIADFYSLKEAGCVAFTDDGSPVMDSS 206 Query: 175 -LYEAFSRCKEIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRA 233 + +A ++G H E+ L ++ G R E R Sbjct: 207 VMRKALELASQLGVPIMDHCEDDKLAYG----VINEGEVSALLGLSSRAPEAEEIQIARD 262 Query: 234 ITIASAVNCPLYIVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAA 293 +A ++I HV +K + ++I + G + E L N A Sbjct: 263 GILAQRTGGHVHIQHVSTKLSLEIIEFFKEKGVKITCEVNPNHLLFTEREVLN----SGA 318 Query: 294 HHVMGPPLRPDPSTPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVE 353 + + PPLR + + + TD+ T +K L + +P G+ G++ Sbjct: 319 NARVNPPLRKKEDRLALIEG-VKRGIIDCFATDHAPHQTFEKELVE---FAMP-GIIGLQ 373 Query: 354 DRMSVIWEKGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRT 413 + + G + + + + + N A+I + G + +GS ADI I+DP Sbjct: 374 TALPSAL-ELYRKGIISLKKLIEMFTINPARIIGV--DLGTLKLGSPADITIFDPNKEWI 430 Query: 414 ISAKTHHQAVNFNIFEGMVCHGVPLVTISRGKVVYEA 450 ++ +T+ G V G + TI GK+VY+ Sbjct: 431 LNEETNLSKSRNTPLWGKVLKGKVIYTIKDGKMVYKD 467 >2Z00-A nrPDB Length = 426 Score = 349 bits (895), Expect = 2e-96, Method: Composition-based stats. Identities = 104/466 (22%), Positives = 176/466 (37%), Gaps = 65/466 (13%) Query: 7 LLIRGGRVVNDDFSE-VADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGID 65 +LIR R+V+ ADVL+ +G + +L +V+D G + PG +D Sbjct: 2 ILIRNVRLVDARGERGPADVLIGEGRILSLEGGE--------AKQVVDGTGCFLAPGFLD 53 Query: 66 THTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWADPKV 125 H H++ P G +D G AA+ GG T ++ + EA + A K Sbjct: 54 LHAHLREP--GEEVKEDLFSGLLAAVRGGYTDLVSMPNTKPPVDTPEAVRALKEKA--KA 109 Query: 126 CCDYSLHVAVTWWSDQ----------VKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLEL 175 LH A Q ++E +L+ D G + + L M Sbjct: 110 LGLARLHPAAALTEKQEGKTLTPAGLLREAGAVLLTDDGRTNEDAGVLAAGLLMAAP--- 166 Query: 176 YEAFSRCKEIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRP-EAVEAEA----- 229 +G VHAE+ L G GP L P EAEA Sbjct: 167 ---------LGLPVAVHAEDAGLRRNGVM------NDGPLADLLGLPGNPPEAEAARIAR 211 Query: 230 ---TLRAITIASAVNCPLYIVHVMSKSAAKVIADARRDGKVVYGE--PIAASLGTDGTHY 284 LR S L++ H+ +K +++ +A+R G V E P +L + Sbjct: 212 DLEVLRYALRRSPATPRLHVQHLSTKRGLELVREAKRAGLPVTAEATPHHLTLTEEALRT 271 Query: 285 WNKEWHHAAHHVMGPPLRPDPSTPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTK 344 ++ + + PPLR + L LL + L TD+ +K D + Sbjct: 272 FDPLFK------VAPPLRGEEDREALLEGLL-DGTLDAIATDHAPHTLAEKE---KDLLR 321 Query: 345 IPNGVNGVEDRMSVIWEKGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIV 404 P G+ +E +++ + R V + + ++ L P + G++A +V Sbjct: 322 APFGIPSLEVAFPLLYTELHLKRGFPLQRLVELFTDGPRRVLGLPPL--HLEEGAEASLV 379 Query: 405 IWDPKGTRTISAKTHHQAVNFNIFEGMVCHGVPLVTISRGKVVYEA 450 + PK R + ++ + G V G P++T+ G++V+EA Sbjct: 380 LLSPK-ERPVDPSAFASKARYSPWAGWVLGGWPVLTLVAGRIVHEA 424 >6HG1-A nrPDB Length = 371 Score = 226 bits (576), Expect = 2e-59, Method: Composition-based stats. Identities = 78/408 (19%), Positives = 134/408 (32%), Gaps = 56/408 (13%) Query: 60 LPGGIDTHTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRS 119 LPG ID H H++ P G +DF GT AAL+GG TM+ + A + Sbjct: 6 LPGLIDVHVHLREP--GGTHKEDFASGTAAALAGGITMVCAMPNTRPPIIDAPALALAQK 63 Query: 120 WADPKVCCDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEAF 179 A+ CD++L + + S+ + G+ + + VT + + Sbjct: 64 LAEAGARCDFALFLGAS--SENAGTLGTVAGSAAGLKLYLANATTNSSHGVTSVVQWMEH 121 Query: 180 SRCKEIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASA 239 HAE + A + +A Sbjct: 122 FETWPSHLPIVAHAEEQTVAA--------------------------------VLMVAQL 149 Query: 240 VNCPLYIVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMGP 299 ++I HV K +I A+ G V E L + E + P Sbjct: 150 TQRSVHICHVARKEEILLIKAAKARGLPVTCEVAPHHLFLSHD---DLERLGPGKGEVRP 206 Query: 300 PLRPDPSTPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVI 359 L N+ + +D+ +K ++ P G G+E + ++ Sbjct: 207 ELGSRQDVEALWENM---AVIDCFASDHAPHTLEEKCG-----SRPPPGFPGLETMLPLL 258 Query: 360 WEKGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTH 419 V G++ + + N +IF+L P++ V D + TI + Sbjct: 259 LT-AVSEGRLSLDDLLQRLHHNPRRIFHLPPQEDT--------YVEVDLEHEWTIPSHMP 309 Query: 420 HQAVNFNIFEGMVCHGVPLVTISRGKVVYEAGVFSVTAGDGKFIPRKP 467 ++ FEG G + RG+V Y G V G G+ + + P Sbjct: 310 FSKAHWTPFEGQKVKGTVRRVVLRGEVAYIDGQVLVPPGYGQDVRKWP 357 >3OOQ-A nrPDB Length = 396 Score = 102 bits (254), Expect = 4e-22, Method: Composition-based stats. Identities = 83/440 (18%), Positives = 133/440 (30%), Gaps = 108/440 (24%) Query: 1 MAAPSRLLIRGGRVVN-DDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLV 59 M+ ++L + V DVLV +G V +G ++ P ++D GK + Sbjct: 1 MSLSVKILFKNATVFPITSRPFKGDVLVSNGKVEKVGENIEDPDA-----EIVDLTGKFL 55 Query: 60 LPGGIDTHTHM-----------------QFPFMGSRSIDDFHQ----GTKAALSGGTTMI 98 PG +D H+H+ P D + AL+GG T + Sbjct: 56 FPGFVDAHSHIGLFEEGVGYYYSDGNEATDPVTPHVKALDGFNPQDPAIERALAGGVTSV 115 Query: 99 IDFAIPQKGGSLIEAFETWRSWADPKVCCD--YSLHVAVTWWSDQVKEEMKIL----VQD 152 + + +RS + L +A +V E K + Sbjct: 116 MIVPGSANPVGGQGSVIKFRSIIVEECIVKDPAGLKMAFGENPKRVYGERKQTPSTRMGT 175 Query: 153 KGV-----NSFKMFMAYKDLYMVTDLELYEAFSRCKEIGAIAQVHAENGDLIAEGAKKML 207 GV K +M K+L E E + E G+++ KK+ Sbjct: 176 AGVIRDYFTKVKNYMKKKELAQKEGKEFTETDLKM-----------EVGEMV--LRKKIP 222 Query: 208 ALGITGPEGHELCRPEAVEAEATLRAITIASAVNCPLYIVHVMSKSAAKVIADARRDGKV 267 A H A+ L AI IA L I H + ++ Sbjct: 223 AR----MHAH--------RADDILTAIRIAEEFGFNLVIEH-----GTEAYKISK----- 260 Query: 268 VYGEPIAASLGTDGTHYWNKEWHHAAHHVMGPPLRPDPSTPDFLMNLLANDDLTTTGTDN 327 V E + + K L T + + LL + L D+ Sbjct: 261 VLAEKKIPVVVGPLLTFRTK-------------LELKDLTMETIAKLLKDGVLIALMCDH 307 Query: 328 CTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIWEKGVHSGKMDENRFVAVTSTNAAKIFN 387 IP V+ ++ + E + + + N AKI Sbjct: 308 ---------------PVIPLEFATVQAATAMRY-------GAKEEDLLKILTVNPAKILG 345 Query: 388 LYPRKGRIAVGSDADIVIWD 407 L R G I G DAD+V+W Sbjct: 346 LEDRIGSIEPGKDADLVVWS 365 >2VUN-A nrPDB Length = 386 Score = 89.8 bits (221), Expect = 3e-18, Method: Composition-based stats. Identities = 42/163 (25%), Positives = 68/163 (41%), Gaps = 17/163 (10%) Query: 5 SRLLIRG-GRVVNDDFSEV----ADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLV 59 S+ +I+ G++V+ D ++VEDG++ A+G + L A ++DAAG V Sbjct: 2 SKTIIKNIGKIVSGDIKSPVLQADTIVVEDGLIAAIGGEELMKDAGDA--TIIDAAGSTV 59 Query: 60 LPGGIDTHTHMQ-FPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQ-KGGSLIEAFETW 117 PG +DTH H+ + + DF +AL GG T +I P G A Sbjct: 60 TPGLLDTHVHVSGGDYAPRQKTMDF---ISSALHGGVTTMISAGSPHFPGRPKDAAGTKA 116 Query: 118 RSWADPKVCCDYSL-----HVAVTWWSDQVKEEMKILVQDKGV 155 + K + H + EE I ++ +GV Sbjct: 117 LAITLSKSYYNARPAGVKVHGGAVILEKGLTEEDFIEMKKEGV 159 >3GIQ-A nrPDB Length = 480 Score = 87.1 bits (214), Expect = 2e-17, Method: Composition-based stats. Identities = 82/449 (18%), Positives = 144/449 (32%), Gaps = 71/449 (15%) Query: 9 IRGGRVVNDDF--SEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGIDT 66 I GG +++ AD+ V DG + A+G GA DA+GK+V PG ID Sbjct: 11 ITGGWIIDGTGAPRRRADLGVRDGRIAAIGE-----LGAHPARHAWDASGKIVAPGFIDV 65 Query: 67 HTH-----MQFPFMGSRSIDDFHQ------GTKAA---LSGGTTMII----DFAIPQKGG 108 H H ++ P + ++ G AA L G T + + + Sbjct: 66 HGHDDLMFVEKPDLRWKTSQGITTVVVGNCGVSAAPAPLPGNTAAALALLGETPLFADVP 125 Query: 109 SLIEAFETWRSWADPKVCCDYS---------LHVAVTWWSDQVKEEMKILVQDKGVNSFK 159 + A + R + ++ A T Q ++M + G F Sbjct: 126 AYFAALDAQRPMINVAALVGHANLRLAAMRDPQAAPTAAEQQAMQDMLQAALEAGAVGFS 185 Query: 160 MFMAYKDLYMVTDLELYEAFSRCKEIGAIAQVHAENG-DLIAEGAKKMLALGI-----TG 213 +AY+ + EL E + H N D + +++LA+G T Sbjct: 186 TGLAYQPGAVAQAAELEGLARVAAERRRLHTSHIRNEADGVEAAVEEVLAIGRGTGCATV 245 Query: 214 PEGHELCRP-EAVEAEATLRAITIASAVNCPLYIVHVMSKSAAKVIADARRDGKV----V 268 H+ P + ATL I A + + ++ ++ R + Sbjct: 246 VSHHKCMMPQNWGRSRATLANIDRAREQGVEVALDIYPYPGSSTILIPERAETIDDIRIT 305 Query: 269 YGEPIA---ASLGTDGTHYWNKEWHHAAHHVMGP----PLRPDPSTPDFLMNLLANDDLT 321 + P D W + AA + P D + Sbjct: 306 WSTPHPECSGEYLADIAARWGCDKTTAARRL-APAGAIYFAMDEDEVKRIFQHPCC---- 360 Query: 322 TTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIWEKGVHSGKMDENRFVAVTSTN 381 G+D + FT+ V+ + M + VA + Sbjct: 361 MVGSDGLPNDARPHPRLWGSFTR-------------VLGRYVREARLMTLEQAVARMTAL 407 Query: 382 AAKIFNLYPRKGRIAVGSDADIVIWDPKG 410 A++F + +G + G+ AD+V++DP Sbjct: 408 PARVFG-FAERGVLQPGAWADVVVFDPDT 435 >2PUZ-A nrPDB Length = 419 Score = 84.4 bits (207), Expect = 1e-16, Method: Composition-based stats. Identities = 70/432 (16%), Positives = 125/432 (28%), Gaps = 76/432 (17%) Query: 23 ADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGIDTHTHMQFPFMGSRSIDD 82 A + V +G + G + P D G+ + P ID HTH+ G + Sbjct: 40 AVIAVRNGRIAFAGPESDLPDDLSTADETTDCGGRWITPALIDCHTHL---VFGGNRAME 96 Query: 83 FHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWADPKVCCDYSLHVAVTWWSDQV 142 F A + I + GG ++ + R+ +D + Q Sbjct: 97 FEMRLNGA------TYEE--IAKAGGGIVSSVRDTRALSDEVLVA-------------QA 135 Query: 143 KEEMKILVQDKGVNSFKMFMAY-----KDLYMVTDLELYEAFSRCKEIGAIAQVHAENGD 197 + L+ + GV++ ++ Y +L M+ E + + + HA D Sbjct: 136 LPRLDTLLSE-GVSTIEIKSGYGLDIETELKMLRVARRLETLRPVRIVTSYLAAHATPAD 194 Query: 198 LIAEGAKKMLALGITGPE-GHELCRPE----AVEAEA-----TLRAITIASAVNCP--LY 245 A + + + G E H + E A R A P L+ Sbjct: 195 YKGRNADYITDVVLPGLEKAHAEGLADAVDGFCEGIAFSVKEIDRVFAAAQQRGLPVKLH 254 Query: 246 IVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMGPPLRPDP 305 + + A++ A +L D Y ++ A Sbjct: 255 AEQLSNLGGAELAAS-------------YNALSADHLEYLDETGAKALA----------- 290 Query: 306 STPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIWE--KG 363 + +L + G + + G S++ G Sbjct: 291 --KAGTVAVLLPGAFYALREKQLPPVQALRDAGA-EIALATDCNPGTSPLTSLLLTMNMG 347 Query: 364 VHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTHHQAV 423 +M + T+ NAAK L G + G AD IWD + + + Sbjct: 348 ATLFRMTVEECLTATTRNAAKALGLLAETGTLEAGKSADFAIWDIERPAEL-----VYRI 402 Query: 424 NFNIFEGMVCHG 435 FN + G Sbjct: 403 GFNPLHARIFKG 414 >1FWC-C nrPDB Length = 567 Score = 78.6 bits (192), Expect = 7e-15, Method: Composition-based stats. Identities = 77/432 (17%), Positives = 125/432 (28%), Gaps = 82/432 (18%) Query: 2 AAPSRLLIRGGRVVNDDFSEVADVLVEDGVVRALG--------HDLLPPGGAPAGLRVLD 53 A L++ +V+ AD+ V+DG + A+G ++ P GA V+ Sbjct: 63 ADCVDLVLTNALIVDHWGIVKADIGVKDGRIFAIGKAGNPDIQPNVTIPIGA--ATEVIA 120 Query: 54 AAGKLVLPGGIDTHTHMQFPFMGSRSIDDFHQGTKAALSGGTTMII---------DFAIP 104 A GK+V GGIDTH H P AL G T ++ A Sbjct: 121 AEGKIVTAGGIDTHIHWICPQQAEE-----------ALVSGVTTMVGGGTGPAAGTHATT 169 Query: 105 -QKGGSLIEAFETWRSWADPKVCCDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMA 163 G I A + + L E GV K+ Sbjct: 170 CTPGPWYISRMLQ----AADSLPVNIGLLGKGNVSQPDALREQVA----AGVIGLKI--- 218 Query: 164 YKDLYMVTDLELYEAFSRCKEIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPE 223 + + T + A + E+ +H+ + G Sbjct: 219 -HEDWGATPAAIDCALTVADEMDIQVALHS------DTLNESGFVEDTLAAIGGRTIHTF 271 Query: 224 AVEAEATLRAITIASAVNCPLYIVHVMSKSAAKVIADARRDGKVVYGEPIAASL-GTDGT 282 E A I I+ + I L Sbjct: 272 HTEGAGGGHAPDII-TACAHPNILPSSTNPTL-----------PYTLNTIDEHLDMLMVA 319 Query: 283 HYWNKEWHHAAHHVMGPPLRPDPSTPDFLMNLLANDDLTTTGTDNCTFNTCQKALGK--D 340 H+ + + R + D L +L + T +D +A+G+ + Sbjct: 320 HHLDPDIAEDVAFAESRIRRETIAAEDVLHDL---GAFSLTSSD-------SQAMGRVGE 369 Query: 341 DFTKIPNGVNGVEDRMSV----IWEKGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIA 396 + V RM V + E+ + R++A + N A + G I Sbjct: 370 VILRTWQ----VAHRMKVQRGALAEETGDNDNFRVKRYIAKYTINPALTHGIAHEVGSIE 425 Query: 397 VGSDADIVIWDP 408 VG AD+V+W P Sbjct: 426 VGKLADLVVWSP 437 >1RK6-A nrPDB Length = 496 Score = 75.5 bits (184), Expect = 5e-14, Method: Composition-based stats. Identities = 98/520 (18%), Positives = 159/520 (30%), Gaps = 100/520 (19%) Query: 2 AAPSRLLIRGGRVVNDDFS--EVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLV 59 A P ++ GG V++ + +ADV V + A+G A + R +D AGK+V Sbjct: 18 ATPFDYILSGGTVIDGTNAPGRLADVGVRGDRIAAVGD-----LSASSARRRIDVAGKVV 72 Query: 60 LPGGIDTHTHMQFPFMGSR-SIDDFHQGTKAALSG--GTTMI-IDFAIPQKGGSLIEA-- 113 PG ID+HTH + R QG ++G G ++ + A P L++ Sbjct: 73 SPGFIDSHTHDDNYLLKHRDMTPKISQGVTTVVTGNCGISLAPLAHANPPAPLDLLDEGG 132 Query: 114 ---------FETWRSWADP--KVCCDYSLHVAVTWWSDQVKEE--------MKILVQDK- 153 + A P C ++ E M+ L D Sbjct: 133 SFRFARFSDYLEALRAAPPAVNAACMVGHSTLRAAVMPDLRREATADEIQAMQALADDAL 192 Query: 154 --GVNSFKMFMAYKDLYMVTDLELYEAFSRCKEIGAIAQVHAENGDLIAEGAKKMLALGI 211 G Y + E+ E G + H + EG + AL Sbjct: 193 ASGAIGISTGAFYPPAAHASTEEIIEVCRPLITHGGVYATH-----MRDEGEHIVQALEE 247 Query: 212 TGPEGHELCRPEAV---------------EAEATLRAITIASAVNCPLY-IVHVMSKSAA 255 T G EL P + E A + A + V+ Y V + Sbjct: 248 TFRIGRELDVPVVISHHKVMGKLNFGRSKETLALIEAAMASQDVSLDAYPYVAGSTMLKQ 307 Query: 256 KVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMGPPLRP---------DPS 306 + A R + + +P G D + + + + P L+P +P Sbjct: 308 DRVLLAGRT-LITWCKPYPELSGRDLEEIAAERGK--SKYDVVPELQPAGAIYFMMDEPD 364 Query: 307 TPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIWEKGVHS 366 +LA T G+D + F + V+ Sbjct: 365 VQ----RILAFGP-TMIGSDGLPHDERPHPRLWGTFPR-------------VLGHYSRDL 406 Query: 367 GKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTHHQAVNFN 426 G V + A F L R G++ G AD+V++DP + Sbjct: 407 GLFPLETAVWKMTGLTAAKFGLAER-GQVQPGYYADLVVFDPATV-----------ADSA 454 Query: 427 IFEGMVCHGVPLV-TISRGKVVYEAGVFSVTAGDGKFIPR 465 FE + G V+E F+ G+ + R Sbjct: 455 TFEHPTERAAGIHSVYVNGAAVWEDQSFTGQH-AGRVLNR 493 >3QGK-C nrPDB Length = 568 Score = 75.1 bits (183), Expect = 6e-14, Method: Composition-based stats. Identities = 75/512 (14%), Positives = 147/512 (28%), Gaps = 96/512 (18%) Query: 7 LLIRGGRVVNDDFSEVADVLVEDGVVRALGH--------DLLPPGGAPAGLRVLDAAGKL 58 L+I +++ AD+ +++G + +G + P G L G + Sbjct: 67 LVITNALIIDYTGIYKADIGIKNGKIHGIGKAGNKDMQDGVTPHMVVGVGTEALAGEGMI 126 Query: 59 VLPGGIDTHTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIID---FAIPQKGGSLIEAFE 115 + GGID+HTH P AL+ G T + + + I Sbjct: 127 ITAGGIDSHTHFLSPQQFPT-----------ALANGVTTMFGGGTGPVDGTNATTITP-G 174 Query: 116 TWRSWADPKVCCDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLEL 175 W + +Y ++V + + + G FK+ + + T + Sbjct: 175 VWNLHRMLRAAEEYGMNVGLLGKGNSSSRAQLVEQVKAGAIGFKL----HEDWGTTPSAI 230 Query: 176 YEAFSRCKEIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAIT 235 S E +H + + + A+ + + E + IT Sbjct: 231 DHCLSVADEYDVQVCIHTDTVNEAGYVDDTLRAMNGRAIHAYHI---EGAGGGHSPDVIT 287 Query: 236 IASAVNCPLYIVHVMSKSAAKVIADARRDGKVVYGEPIAASL-GTDGTHYWNKEWHHAAH 294 +A VN I+ + +A L H+ +K Sbjct: 288 MAGEVN----ILPSSTTPT-----------IPYTINTVAEHLDMLMTCHHLDKRIREDLQ 332 Query: 295 HVMGPPLRPDPSTPDFLMNLLANDDLTTTGTDNCTFNTCQKALGK--DDFTKIPNGVNGV 352 R P + L + T +D +A+G+ + + + Sbjct: 333 FSQS---RIRPGSIAAEDTLHDMGVIAMTSSD-------SQAMGRAGEVIPRTWQTADKN 382 Query: 353 EDRMSVIWEKGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTR 412 + + E+ + R+++ + N A + G + G AD+V+W+P Sbjct: 383 KKEFGRLTEEKGDNDNFRIKRYISKYTINPAITHGVSEYIGSVEEGKIADLVVWNP---- 438 Query: 413 TISAKTHHQAVNFNIFEGMVCHGVPLVTISRGKVVYEA----------------GVFSVT 456 F G+ P + I G VV+ Sbjct: 439 --------------AFFGVK----PKIIIKGGMVVFSEMGDSNASVPTPQPVYYREMFGH 480 Query: 457 AGDGKFIPRKPFAEYIYKRIKQRDRTCTPTPV 488 G KF F + +++ V Sbjct: 481 HGKAKFDTSITFVSKVAYENGIKEKLGLERKV 512 >2VHL-A nrPDB Length = 396 Score = 74.0 bits (180), Expect = 2e-13, Method: Composition-based stats. Identities = 79/454 (17%), Positives = 143/454 (31%), Gaps = 72/454 (15%) Query: 1 MAAPSRLLIRGGRVVNDDFSEV-ADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLV 59 MA LLI+ +V ++ V + DG + + + P + A ++ Sbjct: 1 MAES--LLIKDIAIVTENEVIKNGYVGINDGKISTVSTE---RPKEPYSKEIQAPADSVL 55 Query: 60 LPGGIDTHTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRS 119 LPG ID H H G D S T I+ +P++G + A + Sbjct: 56 LPGMIDIHIH------GGYGADTMD------ASFSTLDIMSSRLPEEGTTSFLATTITQE 103 Query: 120 WAD-PKVCCDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEA 178 + + + A S E + I ++ V+ + K+ +D+EL++ Sbjct: 104 HGNISQALVNAREWKAAEESSLLGAELLGIHLEGPFVSPKRAGAQPKEWIRPSDVELFKK 163 Query: 179 F-SRCKEIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIA 237 + + I + A D E + + I GH +A ++ A Sbjct: 164 WQQEAGGLIKIVTL-APEEDQHFELIRHLKDESIIASMGH---------TDADSALLSDA 213 Query: 238 SAVNCPLYIVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVM 297 + ++ H+ + + + G + + L DG H + A Sbjct: 214 AKAGAS-HMTHLYNAMSPFHHREPGVIGTALAHDGFVTELIADGIH-SHPLAAKLAFLAK 271 Query: 298 GPP---LRPDPSTPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVED 354 G L D L + + + T L K+ G + + Sbjct: 272 GSSKLILITDSMRAKGLKDGVYEFGGQSVTVRGRTALLSDGTL-AGSILKMNEGARHMRE 330 Query: 355 RMSVIWEKGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTI 414 + +TS NAAK ++ RKG + VG DAD+VI Sbjct: 331 -----FTNC------SWTDIANITSENAAKQLGIFDRKGSVTVGKDADLVIVSSDCE--- 376 Query: 415 SAKTHHQAVNFNIFEGMVCHGVPLVTISRGKVVY 448 ++TI RG + + Sbjct: 377 ----------------------VILTICRGNIAF 388 >4CEX-C nrPDB Length = 570 Score = 73.6 bits (179), Expect = 2e-13, Method: Composition-based stats. Identities = 68/416 (16%), Positives = 123/416 (29%), Gaps = 56/416 (13%) Query: 7 LLIRGGRVVNDDFSEVADVLVEDGVVRALGHD--------LLPPGGAPAGLRVLDAAGKL 58 LL+ +++ AD+ V+DG + +G + P V+ A GK+ Sbjct: 69 LLLTNALILDYTGIYKADIGVKDGYIVGIGKGGNPDIMDGVTPNMIVGTATEVIAAEGKI 128 Query: 59 VLPGGIDTHTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAI----PQKGGSLIEAF 114 V GGIDTH H P AL+ G T + K ++ Sbjct: 129 VTAGGIDTHVHFINPDQ-----------VDVALANGITTLFGGGTGPAEGSKATTVTPGP 177 Query: 115 ETWRSWADPKVCCDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLE 174 ++ + + M+ + D G K+ + + T Sbjct: 178 WNIEKMLKSTEGLPINVGILGKGHGSSIAPIMEQI--DAGAAGLKI----HEDWGATPAS 231 Query: 175 LYEAFSRCKEIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAI 234 + + + E +H++ + + A I G H VE A Sbjct: 232 IDRSLTVADEADVQVAIHSDTLNEAGFLEDTLRA--INGRVIHSF----HVEGAGGGHAP 285 Query: 235 TIASAVNCPLYIVHVMSKSAAKVIADARRDGKVVYGEPIAASL-GTDGTHYWNKEWHHAA 293 I + P V+ + + I L H+ + Sbjct: 286 DIMAMAGHP------------NVLPSSTNPTRPFTVNTIDEHLDMLMVCHHLKQNIPEDV 333 Query: 294 HHVMGPPLRPDPSTPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVE 353 R P T L ++ TD + + + ++ Sbjct: 334 AFADS---RIRPETIAAEDILHDLGIISMMSTD-----ALAMGRAGEMVLRTWQTADKMK 385 Query: 354 DRMSVIWEKGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPK 409 + + E+ S R+V+ + N A + G I G AD+V+W+PK Sbjct: 386 KQRGPLAEEKNGSDNFRLKRYVSKYTINPAIAQGIAHEVGSIEEGKFADLVLWEPK 441 >2ICS-A nrPDB Length = 379 Score = 69.0 bits (167), Expect = 5e-12, Method: Composition-based stats. Identities = 72/455 (15%), Positives = 136/455 (29%), Gaps = 86/455 (18%) Query: 1 MAAPSRLLIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAA-GKLV 59 M+ LLI+ G+ VN ++ +++ + A+ + + + + G V Sbjct: 1 MSLDYDLLIKNGQTVNG---MPVEIAIKEKKIAAVAATI-----SGSAKETIHLEPGTYV 52 Query: 60 LPGGIDTHTH-MQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWR 118 G ID H H + + D+ + G T +ID G + E + Sbjct: 53 SAGWIDDHVHCFEKMALYYDYPDEI------GVKKGVTTVIDA-----GTTGAENIHEFY 101 Query: 119 SWADPKVCCDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEA 178 A + L V ++ W ++E+ L + + K D + + Sbjct: 102 DLAQQAKTNVFGL-VNISKWGIVAQDELADLSKVQASLVKKAIQELPDFVVGIKARMSRT 160 Query: 179 FSRCKEIGAIAQVHAENGDLIAEGAKKMLALGITGPE-GHELCRPEAVEAEATLRAITIA 237 + G E AK++ P H P + + Sbjct: 161 V--IGDNGITPL----------ELAKQIQQENQEIPLMVHIGSAPP-----HLDEILALM 203 Query: 238 SAVNCPLYIVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVM 297 + + H + ++ A K + + D H + H A Sbjct: 204 EKGDV---LTHCFNGKENGILDQATDKIKDFAWQAYNKGVVFDIGHGTDSFNFHVA---- 256 Query: 298 GPPLRPDPSTPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMS 357 L + + TD I N NG ++ Sbjct: 257 ----------ETALREGMKAASI---STD----------------IYIRNRENGPVYDLA 287 Query: 358 VIWEKGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKG-TRTISA 416 EK G D + + A+ F+L +KG + +G DAD+ I+ + +T++ Sbjct: 288 TTMEKLRVVG-YDWPEIIEKVTKAPAENFHL-TQKGTLEIGKDADLTIFTIQAEEKTLTD 345 Query: 417 KTHHQAVNFNIFEGMVCHGVPLVTISRGKVVYEAG 451 V P+ TI G++ G Sbjct: 346 SNGLTRVA-------KEQIRPIKTIIGGQIYDNEG 373 >4WGX-A nrPDB Length = 465 Score = 68.2 bits (165), Expect = 9e-12, Method: Composition-based stats. Identities = 84/470 (17%), Positives = 147/470 (31%), Gaps = 54/470 (11%) Query: 7 LLIRGGRVVNDDFSEVA---DVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGG 63 + I GG +++ + V +EDG + +G +R +DA GK +LPG Sbjct: 5 IAIVGGTLIDGNGGVPVPETTVFIEDGRITKVGS--TDQIEVHPNIRQIDAQGKWILPGL 62 Query: 64 IDTHTHMQF--PFMGS-----------RSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSL 110 ++ + H+ MG + + AL GG T + D + ++ Sbjct: 63 VNGNVHLLDGIMMMGRGGIEYLARFEGNYYKVIEEAAQIALRGGVTTVFDTWNALEPVTI 122 Query: 111 IEAFETWRSWADPKVCCDYS---------LHVAVTWWSDQVKEEMKILVQDKGVNSFKMF 161 A + S A ++ S Q + M D+ F++ Sbjct: 123 --ARDRIASGAAEGARIFFAGTLIGMGGPFTGDFMRPSMQARTVMSRTFADRMDAMFEVG 180 Query: 162 MAYKDLYMVTDLELYEAFSRCKEIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCR 221 M + L + E+ E G A L+ G P R Sbjct: 181 MG-RHLSTLPPAEVRPLIREYLERGVDFCKIAVTDHLVGLL-------GFRAPYFTFSER 232 Query: 222 PEAVEAEATLRAITIASAVNCPLYIVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDG 281 V + RA L ++ + A ++ A G+ E L Sbjct: 233 VLDVLVDEVRRAGVPLLTHTTSLEGLNTAIERDADLMIHATMTGQAPIPEETIEKLLEKQ 292 Query: 282 THYWNKEWHHAAHHVMGP---P---LRPDPSTPDFLMNLLANDDLTTTGTDN-CTFNTCQ 334 + A M P + + ++ GTD CT Sbjct: 293 LWSEVQPTTIAQQAWMDSVDHPFADFSGRVHHENDVR-MIKAGVPLVLGTDAGCTDPDIL 351 Query: 335 KALGKDDFTKIPNGVNGVEDRMSVIWEKGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGR 394 + + + + + P + ED +W + + MD + + N AK + + G Sbjct: 352 EDMSQGELHERPWTLG--EDHF--VWMQAMVEKGMDPMAAILAGTANPAKAYRKFDELGS 407 Query: 395 IAVGSDADIVIWDPKGTRTISAKTHHQAVNFNIFEGMV--CHGVPLVTIS 442 I VG D+V+ D I+ V + EG HG+PL + Sbjct: 408 IDVGKLGDVVVLDQDPLADITNMRTLSHV---VKEGREIDFHGLPLSPLV 454 >1E9Y-B nrPDB Length = 569 Score = 65.5 bits (158), Expect = 5e-11, Method: Composition-based stats. Identities = 67/414 (16%), Positives = 120/414 (28%), Gaps = 54/414 (13%) Query: 7 LLIRGGRVVNDDFSEVADVLVEDGVV--------RALGHDLLPPGGAPAGLRVLDAAGKL 58 L+I +V+ AD+ ++DG + + + + L G + Sbjct: 68 LIITNALIVDYTGIYKADIGIKDGKIAGIGKGGNKDMQDGVKNNLSVGPATEALAGEGLI 127 Query: 59 VLPGGIDTHTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWR 118 V GGIDTH H P + F G + GG T D W Sbjct: 128 VTAGGIDTHIHFISPQQIPTA---FASGVTTMIGGG-TGPADGTNATTITPGRRNL-KWM 182 Query: 119 SWADPKVCCDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEA 178 A + + + + + + + G FK+ + + T + A Sbjct: 183 LRAAEEYSMNLGF---LAKGNASNDASLADQI-EAGAIGFKI----HEDWGTTPSAINHA 234 Query: 179 FSRCKEIGAIAQVHAE--NGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITI 236 + +H + N E +A G T H E A I Sbjct: 235 LDVADKYDVQVAIHTDTLNEAGCVEDTMAAIA-GRTMHTFH-------TEGAGGGHAPDI 286 Query: 237 ASAVNCPLYIVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHV 296 I+ + V E + H+ +K Sbjct: 287 IKVAGEH-NILPASTNPTIP---------FTVNTEAEHMDMLMVC-HHKDKSIKEDVQFA 335 Query: 297 MGPPLRPDPSTPDFLMNLLANDDLTTTGTDNCTFNTCQKALGK--DDFTKIPNGVNGVED 354 R P T L + T +D +A+G+ + T+ + + Sbjct: 336 DS---RIRPQTIAAEDTLHDMGAFSITSSD-------SQAMGRVGEVITRTWQTADKNKK 385 Query: 355 RMSVIWEKGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDP 408 + E+ + R+++ + N A + G + VG AD+V+W P Sbjct: 386 EFGRLKEEKGDNDNFRIKRYLSKYTINPAIAHGISEYVGSVEVGKVADLVLWSP 439 >4CQD-A nrPDB Length = 423 Score = 64.7 bits (156), Expect = 9e-11, Method: Composition-based stats. Identities = 81/470 (17%), Positives = 147/470 (31%), Gaps = 82/470 (17%) Query: 1 MAAPSRLLIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVL 60 M+ L+IR + D D+ + + + + +DA G LV Sbjct: 21 MSKDFDLIIRNAYLSEKDSVY--DIGIVGDRIIKIEAKI-----EGTVKDEIDAKGNLVS 73 Query: 61 PGGIDTHTHMQFPFMGS-RSIDDFHQG--TK-AALSGGTTMIIDFAIPQKGGSLIE--AF 114 PG +D HTHM F + + F T+ AA+ G + + +IE Sbjct: 74 PGFVDAHTHMDKSFTSTGERLPKFWSRPYTRDAAIEDGLKYYKNATHEEIKRHVIEHAHM 133 Query: 115 ETWRSWADPKVCCDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVT--- 171 + + D VA T + V E + L + ++ + + V Sbjct: 134 QVLHGTLYTRTHVDVD-SVAKTKAVEAVLEAKEELKD---LIDIQVVAFAQSGFFVDLES 189 Query: 172 DLELYEAFSR-CKEIGAIAQVHAENG-----DLIAEGAKKMLALGITGPEGHELCRPEAV 225 + + ++ C +G + EN DL + AK+ H++ V Sbjct: 190 ESLIRKSLDMGCDLVGGVDPATRENNVEGSLDLCFKLAKEYDVD--IDYHIHDIG---TV 244 Query: 226 EAEATLRAITIASAVNCPLYIVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYW 285 + R +A Y V + SAA ADA + E I Y Sbjct: 245 GVYSINR---LAQKTIENGYKGRVTT-SAAWCFADAPSEWLD---EAIPL--------YK 289 Query: 286 NKEWHHAAHHVMGPPLRPDPSTPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKI 345 + PP P ++ LL +DN DF + Sbjct: 290 DSGMKFVTCFSSTPPTMP-------VIKLLEAGINLGCASDN-----------IRDFW-V 330 Query: 346 PNGVNGVEDRMSVIWEKGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVI 405 P G + + ++ D + ++ A++ + G I VG AD+V+ Sbjct: 331 PFGNGDMVQGALIETQRLELKTNRDLGLIWKMITSEGARVLGIEKNYG-IEVGKKADLVV 389 Query: 406 WDPKGTRTISAKTHHQAVNFNIFEGMVCHGVPLVTISRGKVVYEAGVFSV 455 + + + ++ L I G+++ + V Sbjct: 390 LN----------------SLSPQWAIIDQAKRLCVIKNGRIIVKDEVIVA 423 >2AQV-A nrPDB Length = 390 Score = 63.9 bits (154), Expect = 1e-10, Method: Composition-based stats. Identities = 72/413 (17%), Positives = 133/413 (32%), Gaps = 60/413 (14%) Query: 2 AAPSRLLIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLP 61 A L++G + + + DVLV +G + A+ ++ P V+D +G+++ P Sbjct: 5 TAAGFTLLQGAHLYAPEDRGICDVLVANGKIIAVASNI--PSDIVPNCTVVDLSGQILCP 62 Query: 62 GGIDTHTHMQFPFM-GSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSW 120 G ID H H+ + G T ++ E+ Sbjct: 63 GFIDQHVHLIGGGGEAGPTTRTPEVALSRLTEAGVTSVVGLLGTDSISRHPESLLAKTRA 122 Query: 121 ADPKVCCDYSLHVAVTWWSDQVKE--EMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEA 178 + + + L A S + E + + D+ V K A D ++Y Sbjct: 123 LNEEGISAWMLTGAFHVPSRTITGSVEKDVAIIDR-VIGVKC--AISDHRSAAP-DVYHL 178 Query: 179 FSRCKEIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIAS 238 + E + + G + AL P L + + Sbjct: 179 ANMAAESRVGGLLGGKPGVTVFHMGDSKKALQ---PIYDLL----ENCDVPISKLLPTHV 231 Query: 239 AVNCPLYIVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMG 298 N PL+ + A + AR+ G D T ++ Sbjct: 232 NRNVPLF------EQALE---FARKGG------------TIDITSSIDE----------- 259 Query: 299 PPLRPDPSTPDFLMNL--LANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRM 356 P+ P + LA L++ G + F + + T I GV G E + Sbjct: 260 -PVAPAEGIARAVQAGIPLARVTLSSDGNGSQPFFDDE-----GNLTHI--GVAGFETLL 311 Query: 357 SVIWEKGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPK 409 + + V + + +++ A NL KG I G+DAD+++ P+ Sbjct: 312 ETV-QVLVKDYDFSISDALRPLTSSVAGFLNLTG-KGEILPGNDADLLVMTPE 362 >2OGJ-A nrPDB Length = 417 Score = 63.6 bits (153), Expect = 2e-10, Method: Composition-based stats. Identities = 68/395 (17%), Positives = 121/395 (30%), Gaps = 87/395 (22%) Query: 24 DVLVE-DGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGIDTHTHMQFPFMGSRSIDD 82 D+L+ DG + A+G L P +DA G + PG +D H H+ + G D Sbjct: 37 DILIGGDGKIAAVGSALQAPADTQR----IDAKGAFISPGWVDLHVHI---WHGGT--DI 87 Query: 83 FHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWADPKVCCDYSLHVAVTWWSDQV 142 + ++ G T ++D + + H + + Sbjct: 88 SIRPSECGAERGVTTLVDAG----------------------SAGEANFHGFREYIIEPS 125 Query: 143 KEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEAFSRCKEIGAIAQVHAENGDLIAEG 202 +E +K + + G +L + D++L +AEN + I Sbjct: 126 RERIKAFL-NLGSIGLVACNRVPELRDIKDIDLDRILEC----------YAENSEHIVGL 174 Query: 203 AKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAVNCPLYIVHVMSKSAA-KVIADA 261 + H + V + IA + P+ +VHV A + + Sbjct: 175 KVRA---------SHVITGSWGVTPVKLGK--KIAKILKVPM-MVHVGEPPALYDEVLEI 222 Query: 262 RRDGKVVYGEPIAASLGTDGTH-YWNKEWHHAAHHVMGPPLRPDPSTP------DFLMNL 314 G VV G G+ +++ + A G +R D Sbjct: 223 LGPGDVVT----HCFNGKSGSSIMEDEDLFNLAERCAGEGIRLDIGHGGASFSFKVAEAA 278 Query: 315 LANDDLT-TTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIWEKGVHSGKMDENR 373 +A L + TD + + V + MS + M Sbjct: 279 IARGLLPFSISTDLHGHS-------------MNFPVWDLATTMSKLLSV-----DMPFEN 320 Query: 374 FVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDP 408 V + N A + L R+ VG AD ++D Sbjct: 321 VVEAVTRNPASVIRLDMEN-RLDVGQRADFTVFDL 354 >3MKV-A nrPDB Length = 426 Score = 63.6 bits (153), Expect = 2e-10, Method: Composition-based stats. Identities = 72/449 (16%), Positives = 140/449 (31%), Gaps = 104/449 (23%) Query: 8 LIRGGRVVNDD---FSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGI 64 L R G +++ D + ++L+EDG +R + + V+D GK ++PG I Sbjct: 7 LFRNGALLDPDHPDLLQGFEILIEDGFIREVSD----KPIKSSNAHVIDVKGKTIMPGLI 62 Query: 65 DTHTH-----MQFPFMGSR----SIDDFHQGTKAALSGGTTMIID-----FAIPQKGGSL 110 D H H P + + +A L G T + D + Q S Sbjct: 63 DLHVHVVAIEFNLPRVATLPNVLVTLRAVPIMRAMLRRGFTTVRDAGGAGYPFKQAVESG 122 Query: 111 I----------EAFETWRSWADPKVCCDY-------------SLHVAVTWWSDQVKEEMK 147 + A ADP+ DY V D+V+ ++ Sbjct: 123 LVEGPRLFVSGRALSQTGGHADPRARSDYMPPDSPCGCCVRVGALGRVADGVDEVRRAVR 182 Query: 148 ILVQDKGVNSFKMFMAYKDLYMVTDLELYEAFSRCKEIGAIAQVHAENGDLIAEGAKKML 207 +Q G + K+ MA + TD V + D I + Sbjct: 183 EELQ-MGADQIKI-MASGGVASPTD---------------PVGVFGYSEDEIRAIVAEAQ 225 Query: 208 ALGITGPEGHELCRPEAVEAEATLRAITIASAVNCPLYIVHVMSKSAAKVIADARRDGKV 267 G T H P A RA+ V + +I D Sbjct: 226 GRG-TYVLAHAYT-PA-----AIARAVR-----------CGVRTIEHGNLIDDETARLVA 267 Query: 268 VYGEPIAASLGTDGTHYWNKEWHHAAHHVMGPPLRPDPSTPDFLMNLLANDDLTTTGTDN 327 +G + +L T ++ + + P + + + Sbjct: 268 EHGAYVVPTLVT-----YDALASEGEKYGLPP------------------ESIAKIADVH 304 Query: 328 CTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIWEKG-VHSGKMDENRFVAVTSTNAAKIF 386 + K K+ G + + + + ++ + + + +A + +A++ Sbjct: 305 GA-GLHSIEIMKRAGVKMGFGTDLLGEAQRLQSDEFRILAEVLSPAEVIASATIVSAEVL 363 Query: 387 NLYPRKGRIAVGSDADIVIWDPKGTRTIS 415 + + GRI G+ AD+++ D +++ Sbjct: 364 GMQDKLGRIVPGAHADVLVVDGNPLKSVD 392 >3IV8-A nrPDB Length = 381 Score = 62.0 bits (149), Expect = 6e-10, Method: Composition-based stats. Identities = 70/406 (17%), Positives = 137/406 (33%), Gaps = 59/406 (14%) Query: 11 GGRVVNDDFSEVAD-VLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGIDTHTH 69 ++ + V V++ + A+ P P+ + V+D G + PG ID + Sbjct: 9 NCKIYTGNDVLVKHAVIINGDKIEAV----CPIESLPSEMNVVDLNGANLSPGFIDLQLN 64 Query: 70 MQF--PFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWADPKVCC 127 F + + KA L G T + I ++ +A R + Sbjct: 65 GCGGVMFNDEITAETIDTMHKANLKSGCTSFLPTLITSSDENMRQAIAAAREYQAKYPNQ 124 Query: 128 DYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEAFSRCKEIGA 187 LH+ + + V KG++S D +D + + ++ A Sbjct: 125 SLGLHLEGPYLN----------VMKKGIHSV-------DFIRPSDDTMIDTICANSDVIA 167 Query: 188 IAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRA-ITIASAVNCPLYI 246 + EN E +K++ GI GH EA + + IT A+ ++ Sbjct: 168 KVTLAPENNK--PEHIEKLVKAGIVVSIGH--TNATYSEARKSFESGITFAT------HL 217 Query: 247 VHVMSKSAAKVIADARRDGKV--VYGEP-IAASLGTDGTHYWNKEWHHAAHHVMGPPLRP 303 + M+ R G V +Y P + A + DG H A+ + ++ Sbjct: 218 FNAMTP------MVGREPGVVGAIYDTPEVYAGIIADGFH------VDYANIRIAHKIKG 265 Query: 304 DPSTPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVI--WE 361 + A ++ +K +D NG G +++I + Sbjct: 266 EKLVLVTDATAPAGAEMDYF------IFVGKKVYYRDGKCVDENGTLG-GSALTMIEAVQ 318 Query: 362 KGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWD 407 V + + + + + AK + + GRI G A++ ++D Sbjct: 319 NTVEHVGIALDEALRMATLYPAKAIGVDEKLGRIKKGMIANLTVFD 364 >3HPA-A nrPDB Length = 479 Score = 60.9 bits (146), Expect = 1e-09, Method: Composition-based stats. Identities = 92/480 (19%), Positives = 153/480 (31%), Gaps = 78/480 (16%) Query: 2 AAPSRLLIRGGRV-VNDDFSEV----ADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAG 56 + P LL++ V V D + A + +ED + A+G P VLD G Sbjct: 26 SRPKTLLVKHADVLVTMDDTRRELRDAGLYIEDNRIVAVGPSAELPE---TADEVLDLRG 82 Query: 57 KLVLPGGIDTHTHMQFPFMGSRSIDDFHQGTKAALSGGTTM---IIDFAIPQK-GGSLIE 112 LV+PG ++TH HM + A L G T I P+ S + Sbjct: 83 HLVIPGLVNTHHHMYQSLTRAVPA-----AQNAELFGWLTNLYKIWAHLTPEMIEVSTLT 137 Query: 113 AFETWRSWADPKVCCDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTD 172 A ++ + D + +I ++ M + +D + D Sbjct: 138 AMAELLQSGCTTSSDHLYIYPNGSRLDDSIGAAQRIGMRFHASRG-AMSVGQRDGGLPPD 196 Query: 173 LELYEAFSRCKEIGAIAQV-HAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATL 231 + ++ + + H EG ML + + C P +V + Sbjct: 197 SVVEREPDILRDTQRLIETYH-------DEGRYAMLRVVV------APCSPFSVSRDLMR 243 Query: 232 RAITIASAVNCPLYIVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHH 291 A +A L+ H+ IA +R +G A D + WH Sbjct: 244 DAAVLAREYGVSLH-THL--AENVNDIAYSREK----FGMT-PAEYAEDLGWVGHDVWHA 295 Query: 292 AAHHVMGPPLRPDPSTPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKI------ 345 + D + L A T TG +C + + A G K+ Sbjct: 296 HCVQL-----------DDAGIGLFAR---TGTGVAHCPCSNMRLASGIAPVKKMRLAGVP 341 Query: 346 -PNGVNGV----------EDRMSVIWEK-GVHSGKMDENRFVAVTSTNAAKIFNLYPRKG 393 GV+G E R +++ ++ G M + + + AK+ N G Sbjct: 342 VGLGVDGSASNDGAQMVAEVRQALLLQRVGFGPDAMTAREALEIATLGGAKVLN-RDDIG 400 Query: 394 RIAVGSDADIVIWDPKGTRTISAKTHHQAVNFNIFEGMVCHGVPLVTISRGKVVYEAGVF 453 + G AD +D + + A H V +F T+ GKVV G Sbjct: 401 ALKPGMAADFAAFDLRQP--LFAGALHDPVAALVFCA---PSQTAYTVVNGKVVVREGRL 455 >2PLM-A nrPDB Length = 406 Score = 60.9 bits (146), Expect = 1e-09, Method: Composition-based stats. Identities = 76/473 (16%), Positives = 147/473 (31%), Gaps = 115/473 (24%) Query: 7 LLIRGGRVVND--DFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGI 64 ++I ++ D V +E+G ++ + + LD +GKLV+P Sbjct: 1 MIIGNCLILKDFSSEPFWGAVEIENGTIKRVLQGEVKVD--------LDLSGKLVMPALF 52 Query: 65 DTHTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWADPK 124 +THTH + + D +FE W Sbjct: 53 NTHTHAPMTLLRGVAED------------------------------LSFEEW------- 75 Query: 125 VCCDYSLHVAVTWWSDQVKEEM--------KILVQDKGVNSFKMFMAYKD--LYMVTDLE 174 L V D++ E+M ++ + G+ F +++ V D Sbjct: 76 ------LFSKVLPIEDRLTEKMAYYGTILAQMEMARHGIAGFVDMYFHEEWIAKAVRDFG 129 Query: 175 LYEAFSRCKEIGAIAQVHAENGDLIAEGAKKMLA----LGITGPEGHELCRPEAVEAEAT 230 + +R + + ++G + E K G P E Sbjct: 130 MRALLTR-----GLVDSNGDDGGRLEENLKLYNEWNGFEGRIFVGFGPHS-PYLCSEEYL 183 Query: 231 LRAITIASAVNCPLYIVHV--MSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKE 288 R A ++N P+ I H+ SK + + + G ++ H + Sbjct: 184 KRVFDTAKSLNAPVTI-HLYETSKEEYDL------EDILNIGLKEVKTIAAHCVHLPERY 236 Query: 289 WHHAAH---HVMGPPLRPDPSTPDF--LMNLLANDDLTTTGTDNCTFNTCQKALGKDDFT 343 + V P + ++ + T GTD N Sbjct: 237 FGVLKDIPFFVSHNPASNLKLGNGIAPVQRMIEHGMKVTLGTDGAASN------------ 284 Query: 344 KIPNGVNGV-EDRMSVIWEKGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDAD 402 N +N E R++ + +K + +D N + + + + A+ + G+I G +AD Sbjct: 285 ---NSLNLFFEMRLASLLQKAQNPRNLDVNTCLKMVTYDGAQAMGF--KSGKIEEGWNAD 339 Query: 403 IVIWDPKGTR--TISAKTHHQAVNFNIFEGMVCHGVPLVTISRGKVVYEAGVF 453 +V+ D + +H F+ G T+ GK +Y G + Sbjct: 340 LVVIDLDLPEMFPVQNIKNHLVHAFS--------GEVFATMVAGKWIYFDGEY 384 >3DUG-A nrPDB Length = 408 Score = 60.9 bits (146), Expect = 1e-09, Method: Composition-based stats. Identities = 70/462 (15%), Positives = 132/462 (28%), Gaps = 92/462 (19%) Query: 10 RGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGIDTHTH 69 +G + AD+L+ +G + +G V+ +++PG +D+H H Sbjct: 13 KGYLDIQTGEIIKADLLIRNGKIAEIGK------INTKDATVISIPDLILIPGLMDSHVH 66 Query: 70 MQFPFMGSRS--IDDFHQGT-------KAALSGGTTMIIDFAIPQ-KGGSLIEAFETWRS 119 + D H GT + L G T + + S+ +A E R Sbjct: 67 IVGNDSKGEESIADSSHMGTVWGVVNAEKTLMAGFTTVRNVGAANYADVSVRDAIE--RG 124 Query: 120 WADPKVCCDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEAF 179 + + +T L+ + F + + + E + Sbjct: 125 VINGPTMLVSGPALGITGGHCD-----HNLLPPE-------FNYSSEGVVDSPWEARKMV 172 Query: 180 SRCKEIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASA 239 + ++ GA G +++ + L +A+ EA + +A+ Sbjct: 173 RKNRKYGADLIKFCATGGVMSRNTD-------VNAKQFTLEEMKAIVDEAHNHGMKVAAH 225 Query: 240 VNCPLYIVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHY-WNKEWHHAAHHVMG 298 + + I K+ + A I + + + A Sbjct: 226 AHGLIGI-KAAIKAGVDSVEHASFIDDETIDMAIKNNTVLSMDIFVSDYILGEGAKAG-- 282 Query: 299 PPLRPDPSTPDFL---------MNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGV 349 +R + + L MN + T GTD F+ +G Sbjct: 283 --IREESLNKERLVGKKQRENFMNAHRRGAIITFGTDAGIFD---------------HGD 325 Query: 350 NGVEDRMSVIWEKGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPK 409 N + V W M + ++ A +F + G+I G DADIV Sbjct: 326 NAKQFAYMVEW-------GMTPLEAIQASTIKTATLFGI-ENIGQIKEGFDADIV----- 372 Query: 410 GTRTISAKTHHQAVNFNIFEGMVCHGVPLVTISRGKVVYEAG 451 I N + + GKV G Sbjct: 373 --GVIE----------NPLANIRTLEEVAFVMKEGKVYKREG 402 >4Z42-C nrPDB Length = 572 Score = 60.1 bits (144), Expect = 2e-09, Method: Composition-based stats. Identities = 83/505 (16%), Positives = 149/505 (29%), Gaps = 82/505 (16%) Query: 7 LLIRGGRVVNDD-FSEVADVLVEDGVVRALGH--DLLPPGGAPAGLRV------LDAAGK 57 L+I +V+ ADV + DG + +G + G GL V + Sbjct: 70 LVITNVTIVDARLGVIKADVGIRDGKIAGIGKSGNPGVMDGVTPGLVVGVSTDAISGEHL 129 Query: 58 LVLPGGIDTHTHMQFPFMGSRSIDDFHQGTKAALSGGT--TMIIDFAIPQKGGSLIEAFE 115 ++ GIDTH H+ P ++ G GG T + G + Sbjct: 130 ILTAAGIDTHIHLISP---QQAYHALSNGVATFFGGGIGPTDGTNGTTVTPGP--WNIRQ 184 Query: 116 TWRSWADPKVCCDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLEL 175 RS V L ++ + E+ GV +K+ + + T L Sbjct: 185 MLRSVEGLPVNVG-ILGKGNSYGRGPLLEQ-----AIAGVVGYKV----HEDWGATANAL 234 Query: 176 YEAFSRCKEIGAIAQVHAENGDLIAEGAKKMLA-LGITGPEGHELCRPEAVEAEATLRAI 234 + E+ VH ++ + + A G T H E I Sbjct: 235 RHSLRMADEMDIQVSVHTDSLNECGYVEDTIDAFEGRTIHTFHT----EGAGGGHAPDII 290 Query: 235 TIASAVNCPLYIVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAH 294 +AS N ++ + G E + + A Sbjct: 291 RVASQPN----VLPSSTNPTLPY-------GVNSQAELFDMIMVCHNLNPNVPADVSFAE 339 Query: 295 HVMGPPLRPDPSTPDFLMNLLANDDLTTTGTDNCTFNTCQKALGK--DDFTKIPNGVNGV 352 R P T L ++ +D +A+G+ +++ ++ N + Sbjct: 340 S------RVRPETIAAENVLHDMGVISMFSSD-------SQAMGRVGENWLRVMQTANAM 386 Query: 353 EDRMSVIWEKGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTR 412 + + E + R+VA + N A + G + VG AD+V+WDP Sbjct: 387 KASRGKLPEDAPGNDNFRVLRYVAKITINPAIAQGVSHVIGSVEVGKMADLVLWDP---- 442 Query: 413 TISAKTHHQAVNFNIFEGMVCHGVPLVTISRGKVVYEAGVFSVTAGDGKFIPRKPFAEYI 472 P + I G + + A P+ F + Sbjct: 443 ------------------RFFGAKPKMVIKGGMINWAA---MGDPNASLPTPQPVFYRPM 481 Query: 473 YKRIKQRDRTCTPTPVERAPYKGEV 497 + + + + T V +A V Sbjct: 482 FGAMGKTMQDTCVTFVSQAALDDGV 506 >4V1Y-A nrPDB Length = 494 Score = 58.6 bits (140), Expect = 6e-09, Method: Composition-based stats. Identities = 40/123 (32%), Positives = 50/123 (40%), Gaps = 34/123 (27%) Query: 7 LLIRGGRVVNDDFSEV--AD--VLVEDGVVRALG-HDLLPPGGAPAGLRVLDAAGKLVLP 61 L I+ G +V D D V V+DG + ALG H P P RV+DA GK+VLP Sbjct: 24 LSIQHGTLVTMDQYRRVLGDSWVHVQDGRIVALGVHAESVP---PPADRVIDARGKVVLP 80 Query: 62 GGIDTHTHMQF------PFMGSRSIDDFHQ----GTKA----------------ALSGGT 95 G I+ HTH+ P G + D G KA A+ G Sbjct: 81 GFINAHTHVNQILLRGGPSHGRQFYDWLFNVVYPGQKAMRPEDVAVAVRLYCAEAVRSGI 140 Query: 96 TMI 98 T I Sbjct: 141 TTI 143 Score = 42.8 bits (99), Expect = 4e-04, Method: Composition-based stats. Identities = 16/90 (17%), Positives = 32/90 (35%), Gaps = 5/90 (5%) Query: 369 MDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTHHQAVNFNIF 428 + + + + + + A+ + G I G AD+++ D + +T HH +F Sbjct: 378 LTPEKILEMATIDGARSLGMDHEIGSIETGKRADLILLDLRHPQT---TPHHHLAATIVF 434 Query: 429 EGMVCHGVPLVTISRGKVVYEAGVFSVTAG 458 + + G VV E S Sbjct: 435 QAY--GNEVDTVLIDGNVVMENRRLSFLPP 462 >3T8L-A nrPDB Length = 608 Score = 57.4 bits (137), Expect = 1e-08, Method: Composition-based stats. Identities = 20/67 (29%), Positives = 33/67 (49%), Gaps = 6/67 (8%) Query: 7 LLIRGGRVVN--DDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGI 64 +LI GG +V+ AD+ + ++ ++ P +V+DA G V PG I Sbjct: 37 VLITGGTLVDVVTGELRPADIGIVGALIASVHE----PASRRDAAQVIDAGGAYVSPGLI 92 Query: 65 DTHTHMQ 71 DTH H++ Sbjct: 93 DTHMHIE 99 >2BB0-A nrPDB Length = 421 Score = 56.6 bits (135), Expect = 3e-08, Method: Composition-based stats. Identities = 64/394 (16%), Positives = 115/394 (29%), Gaps = 41/394 (10%) Query: 23 ADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGIDTHTHMQFPFMGSRSIDD 82 A V + + + G ++D +G+LV PG +D HTH+ F GSR + Sbjct: 38 AVVGIHEQKIVFAGQK--GAEAGYEADEIIDCSGRLVTPGLVDPHTHL--VFGGSREKE- 92 Query: 83 FHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWADPKVCCDYSLHVAVTWWSDQV 142 L G +D I +GG ++ + R+ ++ ++ H+ Sbjct: 93 ----MNLKLQG--ISYLD--ILAQGGGILSTVKDTRAASEEELLQKAHFHLQRMLSYGTT 144 Query: 143 KEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEAFSRCKEIGAIAQVHAENGDLIAEG 202 E+K + K K L+ ++L F I + + D + + Sbjct: 145 TAEVKSGYGLEKETELKQLRVAKKLHESQPVDLVSTFMGAHAI--PPEYQNDPDDFLDQM 202 Query: 203 AKKM--LALGITGPEGHELCRPEAVEAEATLRAITIASAVNCPLYIVHVMSKSAAKVIAD 260 + + + R + A+ L I H + Sbjct: 203 LSLLPEIKEQELASFADIFTETGVFTVSQSRRYLQKAAEAGFGLKI-H---ADEIDPLGG 258 Query: 261 ARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMGPPLRPDPSTPDFLMNLLANDDL 320 A GK+ +D E A + G ST ++ Sbjct: 259 AELAGKLKAVSADHLVGTSDEGIKKLAEAGTIAVLLPGTTFYLGKSTYARARAMIDEGVC 318 Query: 321 TTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIWEKGVHSGKMDENRFVAVTST 380 + TD ++ + + +I KM + Sbjct: 319 VSLATDFNPGSSPT-------------------ENIQLIMSIAALHLKMTAEEIWHAVTV 359 Query: 381 NAAKIFNLYPRKGRIAVGSDADIVIWD-PKGTRT 413 NAA G++ G AD+VIW P Sbjct: 360 NAAYAIGKGEEAGQLKAGRSADLVIWQAPNYMYI 393 >5T5I-A nrPDB Length = 569 Score = 56.2 bits (134), Expect = 3e-08, Method: Composition-based stats. Identities = 21/66 (31%), Positives = 35/66 (53%), Gaps = 12/66 (18%) Query: 8 LIRGGRV---VNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGI 64 +I+ G V +N E D+ V+DG + +V+DA+GK+V+PGG+ Sbjct: 4 IIKNGFVYCPLNGVDGEKMDICVKDGKIVE---------SVSDSAKVIDASGKIVMPGGV 54 Query: 65 DTHTHM 70 D H+H+ Sbjct: 55 DPHSHI 60 Score = 53.5 bits (127), Expect = 2e-07, Method: Composition-based stats. Identities = 19/95 (20%), Positives = 37/95 (38%), Gaps = 9/95 (9%) Query: 367 GKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTHHQAVNFN 426 + + +T +AK+ L KG + VG+DADI ++D T+ + A+ Sbjct: 431 REYTFSEIAQITRATSAKVLGLSDTKGHLGVGADADIAVYDIN-PETVDPSAEYMAIE-- 487 Query: 427 IFEGMVCHGVPLVTISRGKVVYEAGVFSVTAGDGK 461 + G++V + G + G+ Sbjct: 488 -----EAFSRAACVLKDGEIVVKDGEVVASP-HGR 516 >4H9M-A nrPDB Length = 840 Score = 55.9 bits (133), Expect = 5e-08, Method: Composition-based stats. Identities = 22/106 (20%), Positives = 39/106 (36%), Gaps = 19/106 (17%) Query: 2 AAPSRLLIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGA--------PAGLRVLD 53 A +I +++ AD+ ++DG++ ++G P A V+ Sbjct: 334 AISLDTVITNAVIIDYTGIIKADIGIKDGLIASIGKAGNPDIMNGVFSNMIIGANTEVIA 393 Query: 54 AAGKLVLPGGIDTHTHMQFPFMGSRSIDDFHQGTKAALSGGTTMII 99 G +V G ID H H P + A+S G T ++ Sbjct: 394 GEGLIVTAGAIDCHVHYICPQLVYE-----------AISSGITTLV 428 Score = 35.1 bits (79), Expect = 0.083, Method: Composition-based stats. Identities = 18/83 (21%), Positives = 26/83 (31%), Gaps = 22/83 (26%) Query: 368 KMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTHHQAVNFNI 427 R++A + N A G + VG AD+V+W P Sbjct: 670 NFRIRRYIAKYTINPAIANGFSQYVGSVEVGKLADLVMWKPS------------------ 711 Query: 428 FEGMVCHGVPLVTISRGKVVYEA 450 F G P + I G V + Sbjct: 712 FFGTK----PEMVIKGGMVAWAD 730 >4R7W-A nrPDB Length = 431 Score = 55.5 bits (132), Expect = 5e-08, Method: Composition-based stats. Identities = 65/453 (14%), Positives = 125/453 (27%), Gaps = 65/453 (14%) Query: 9 IRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGIDTHT 68 I R+ + D+ +DG++ + +DA G+L +P ++ H Sbjct: 3 IINARLRRQEALFTLDL--QDGIIHRITAQAAMQTADAGA---IDAQGRLAIPPFVEPHI 57 Query: 69 HMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWADPKVCCD 128 H+ + GT L G T + Sbjct: 58 HLDATLTAGEP-EWNRSGT---LFEGITRWSQRKASITPEDTRQRALKTIGMLRDFGVQH 113 Query: 129 YSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEAFSRCKEIGAI 188 HV VT S + + + Q+ +A+ + + E +R E+GA Sbjct: 114 VRTHVDVTDPSLAALQALLAVKQEAADLIDLQIVAFPQEGIESYPNGRELMTRAIEMGAD 173 Query: 189 AQ---VHAENG-----DLIAEGAKKMLALGI-TGPEGHELCRPEAVEAEATLRAITIASA 239 H EN + G E+ P++ E + Sbjct: 174 VVGGIPHYENTRDKGVSSVMFLMDLAQRYGRLVDVHCDEIDDPQSRFLEVLAEEARVRG- 232 Query: 240 VNCPLYIVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHA---AHHV 296 + + H + + Y + L G ++ + Sbjct: 233 MGAQVTASHTCAMGSYD----------NAYCSKLFRLLKASGINFISCPTESIHLQGRFD 282 Query: 297 MGPPLRPDPSTPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRM 356 P R + + D + LG + +I + + + Sbjct: 283 SWPKRRGVTRVAELDRAGIN----VCFAQD--SIQDPWYPLGNGNILRILDAGLHICHML 336 Query: 357 SVIWEKGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISA 416 G D R + + N+A+ L G +A G A+++I D + Sbjct: 337 ----------GYDDLQRCLDFVTDNSARALCLGDNYG-LAEGRPANLLILDAE------- 378 Query: 417 KTHHQAVNFNIFEGMVCHGVPLVTISRGKVVYE 449 N +E + L +I GKV+ + Sbjct: 379 ---------NDYEAVRRQARVLTSIRHGKVILQ 402 >5XGX-A nrPDB Length = 395 Score = 55.1 bits (131), Expect = 7e-08, Method: Composition-based stats. Identities = 71/420 (16%), Positives = 122/420 (29%), Gaps = 68/420 (16%) Query: 7 LLIRGGRVVNDDFSEVADVLVEDGVVRAL---GHDLLPPGGAPAGLRVLDAAGKLVLPGG 63 +L+ + + + DVL+ + A+ G + ++V++ G ++ PG Sbjct: 9 ILLCNVNIYAPNPLGIKDVLIAGNKIAAIYDHGQGEITIPKQWP-VKVINFDGAILTPGF 67 Query: 64 IDTHTHMQFPFMGSRSIDDFHQ-----GTKAALSGGTTMIIDFA----IPQKGGSLIEAF 114 ID+H H+ G F G G T ++ + +L+ Sbjct: 68 IDSHAHI----TGGGGQAGFATQVPPVGLTEFTHAGVTTVVGLLGTDDTTRSTENLLSRV 123 Query: 115 ETWRSWADPKVCCDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLE 174 R C H +T + K ++ L G+ F + + T E Sbjct: 124 YGLREEGLSAYCWTGGYHFPLTTITGSAKSDIAFLEPVIGIGEFAI--SDHRSSQPTFEE 181 Query: 175 LYEAFSRCKEIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAI 234 + S G I G G L E E RAI Sbjct: 182 VIRLASETHVAGLIT--------------------GKAGVIHFHLGDGER-RLELIERAI 220 Query: 235 TIASAVNCPLYIVHVM-SKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAA 293 HV +K + G L W Sbjct: 221 RETELPARVFNPTHVNRNKPLFEDSCKLLSKG-------CHIDLTAFPAGTAQPGWEACD 273 Query: 294 HHVMGPPLRPDPSTPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVE 353 M L + L++ G Q L DF + + + Sbjct: 274 AIEMA------VERQLPLEQI----TLSSDGGGCLPCFDPQGELQHMDFGRA----STLG 319 Query: 354 DRMSVIWEKGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRT 413 + + KG + + + ++N A I + KG+IAVG DAD+++ + K T Sbjct: 320 ETLVATLNKG-----LSLETVLPMLTSNVANILR-FKNKGQIAVGFDADLLVMNEKYEIT 373 >1O12-A nrPDB Length = 376 Score = 55.1 bits (131), Expect = 7e-08, Method: Composition-based stats. Identities = 78/456 (17%), Positives = 143/456 (31%), Gaps = 107/456 (23%) Query: 7 LLIRGGRVVND-DFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGID 65 +++ +V+ D DV +E+G + + P G +++PG +D Sbjct: 13 MIVEKVLIVDPIDGEFTGDVEIEEGKIVKVEKRECIPRG-------------VLMPGFVD 59 Query: 66 THTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWA-DPK 124 H H DF + + S G T + + + E R + + Sbjct: 60 PHIH--GVVGADTMNCDFSEMEEFLYSQGVTTFLATTVSTSLEKMKEILRKARDYILENP 117 Query: 125 VCCDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEAFSRCKE 184 +H+ + S + KG +S K + ++ EL E S K Sbjct: 118 STSLLGVHLEGPYISKE----------KKGAHSEKH------IRPPSERELSEIDSPAKM 161 Query: 185 IGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVE---AEATLRAITIASAVN 241 + ++ E+ +L+ K+ I GH + E E R + + Sbjct: 162 LTFAPEI--ESSELLLRLVKR----DIVLSAGHSIATFEEFMKFYKEGVKRITHFPNGLK 215 Query: 242 CPLYIVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMGPPL 301 PL+ H + G + + + L DG H + + Sbjct: 216 -PLH--H----------REIGITGAGLLLDDVKLELICDGVHLSREMVKLVYKVKKANGI 262 Query: 302 RPDPSTPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRM----S 357 + L + TT G D K+ +GV +ED + Sbjct: 263 VLVTDSISA--AGLKDGT-TTLG---------------DLVVKVKDGVPRLEDGTLAGST 304 Query: 358 VIWEKGVHS-GKMD---ENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRT 413 + + + V + K V+S N+ L +GRIA G+ AD+V+ D Sbjct: 305 LFFSQAVKNFRKFTGCSITELAKVSSYNSCVELGL-DDRGRIAEGTRADLVLLDEDL--- 360 Query: 414 ISAKTHHQAVNFNIFEGMVCHGVPLVTISRGKVVYE 449 ++TI G+VV+ Sbjct: 361 ----------------------NVVMTIKEGEVVFR 374 >5VGM-A nrPDB Length = 345 Score = 54.7 bits (130), Expect = 9e-08, Method: Composition-based stats. Identities = 49/283 (17%), Positives = 85/283 (30%), Gaps = 48/283 (16%) Query: 65 DTHTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSW---A 121 D H H++ + + ++ D + AL + E +R A Sbjct: 14 DWHVHLRDGDVLADTVRDISRYNGRALI--------MPNTVPPVTTTEMALAYRERIMAA 65 Query: 122 DPKVCCDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMA----YKDLYMVTDLELYE 177 P+ + +A+ + EE++ V + K++ A D + + +Y Sbjct: 66 QPQAH--FEPLMALYLTDNTSPEEIRKAKASGKVVAAKLYPAGATTNSDSGVTSAKNIYP 123 Query: 178 AFSRCKEIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIA 237 +E+G + VH E +T E R E T +A Sbjct: 124 VLQAMQEVGMLLLVHGE----------------VTTHEVDIFDR------EKTFLDTVLA 161 Query: 238 SAVN--CPLYIV--HVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAA 293 VN L IV H+ + A + A G V A L + H Sbjct: 162 PIVNDFPQLKIVLEHITTADAVTFVQQA---GDNVAATITAHHLLFNRNHMLVGGIRP-- 216 Query: 294 HHVMGPPLRPDPSTPDFLMNLLANDDLTTTGTDNCTFNTCQKA 336 H P L+ + + GTD+ +K Sbjct: 217 HFYCLPILKRATHQHALVAAATSGSKKFFLGTDSAPHAKGRKE 259 >4G7E-B nrPDB Length = 840 Score = 54.3 bits (129), Expect = 1e-07, Method: Composition-based stats. Identities = 20/106 (18%), Positives = 38/106 (35%), Gaps = 19/106 (17%) Query: 2 AAPSRLLIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPP--------GGAPAGLRVLD 53 A +I +++ AD+ ++DG++ ++G P V+ Sbjct: 334 ALSLDTVITNAVIIDYSGIIKADIGIKDGLIHSIGKSGNPDVMDGVFQNMTTGVNTEVIA 393 Query: 54 AAGKLVLPGGIDTHTHMQFPFMGSRSIDDFHQGTKAALSGGTTMII 99 G +V G ID H H P + A++ G T ++ Sbjct: 394 GEGLIVTAGAIDCHVHYICPQLVYE-----------AVTSGITTLV 428 Score = 38.1 bits (87), Expect = 0.010, Method: Composition-based stats. Identities = 28/151 (18%), Positives = 48/151 (31%), Gaps = 27/151 (17%) Query: 368 KMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTHHQAVNFNI 427 R+VA + N A G + VG AD+V+W P Sbjct: 670 NFRIKRYVAKYTINPAIANGFSQYVGSVEVGKLADLVMWKPSF----------------- 712 Query: 428 FEGMVCHGVPLVTISRGKVVYEA-GVFSVTAGDGKFIPRKPFAEYIYKRIKQRDRTCTPT 486 P + I G+V Y G + + + + +P +Y + + + Sbjct: 713 -----FGAKPEMVIKGGEVAYANMGDPNASIPTPEPVKMRP----MYGALGKAGGALSIA 763 Query: 487 PVERAPYKGEVATLKSRVTKEDATAGTRKQA 517 V +A V L + +A + RK Sbjct: 764 FVSKAALDQRVKVLYGLNKRVEAVSNVRKLT 794 >3N2C-A nrPDB Length = 423 Score = 52.8 bits (125), Expect = 4e-07, Method: Composition-based stats. Identities = 77/414 (18%), Positives = 128/414 (30%), Gaps = 88/414 (21%) Query: 24 DVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGIDTHTHMQFPFMGSRSIDDF 83 V+++ + + + +D GK V+PG ID H H+ + ++ Sbjct: 26 HVVIDGERIVEVTD----RPVDLPNAQAIDVRGKTVMPGFIDCHVHV-LASNANLGVNAT 80 Query: 84 HQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWADPKVCCDYSLHVAVT---WWSD 140 AA+ ++P L F + R D+SL AV Sbjct: 81 QPNILAAIR---------SLPILDAMLSRGFTSVRDAGG----ADWSLMQAVETGLVSGP 127 Query: 141 QVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEAFSRCKEIGAIAQV--------H 192 ++ K L Q G F+ +L E S C GAIA+V Sbjct: 128 RIFPSGKALSQTGGHGDFR-----------PRGDLLEPCSCCFRTGAIARVVDGVEGVRL 176 Query: 193 AENGDLIAEGAK-KMLALGI----TGPEG-----HELCRPEAVEAEATLRAIT---IASA 239 A ++ + K++A G T P + R EAEA + Sbjct: 177 AVREEIQKGATQIKIMASGGVASPTDPIANTQYSEDEIRAIVDEAEAANTYVMAHAYTGR 236 Query: 240 VNCPLYIVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMGP 299 V + ++ +A +G + +L T ++ H A M P Sbjct: 237 AIARAVRCGVRTIEHGNLVDEAAAKLMHEHGAFVVPTLVT-----YDALAKHGAEFGM-P 290 Query: 300 P------LRPDPSTPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVE 353 P + L G+D A +F + +E Sbjct: 291 PESVAKVASVQQKGRESLEIYANAGVKMGFGSD---LLGEMHAFQSGEFRIRAEVLGNLE 347 Query: 354 DRMSVIWEKGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWD 407 + +T AA+I N+ + G IAVG+ AD+V+ D Sbjct: 348 A--------------------LRSATTVAAEIVNMQGQLGVIAVGAIADLVVLD 381 >4DYK-A nrPDB Length = 451 Score = 52.0 bits (123), Expect = 6e-07, Method: Composition-based stats. Identities = 68/458 (14%), Positives = 128/458 (27%), Gaps = 97/458 (21%) Query: 25 VLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGIDTHTHMQF------------ 72 + + DG + + + + G L+ PG ++ H H Sbjct: 32 LGIRDGQIALVAPREQAMRHG--ATEIRELPGMLLAPGLVNAHGHSAMSLFRGLADDLPL 89 Query: 73 ---------PFMGSRSIDDF-HQGTKAALS----GGTTMIIDFAIPQKGGSLIEAFETWR 118 P G +DF GT+ A++ GG T D ++ Sbjct: 90 MTWLQDHIWPAEGQWVSEDFIRDGTELAIAEQVKGGITCFSDMYF--YPQAICGVVHDSG 147 Query: 119 SWADPKVCCDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEA 178 A + ++ +++ M + K ++ Y V+D +L + Sbjct: 148 VRAQVAIPVLDFPIPGARDSAEAIRQGMALFDDLKHHPRIRIAFGPHAPYTVSDDKLEQI 207 Query: 179 FSRCKEIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIAS 238 +E+ A Q+H + E + M G L R R + Sbjct: 208 LVLTEELDASIQMHVH--ETAFEVEQAMERNGER-----PLAR--------LHRLGLL-- 250 Query: 239 AVNCPLYIVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMG 298 VH+ + + V++ P + G K W + +G Sbjct: 251 --GPRFQAVHMTQVDNDDLAMLVETNSSVIHC-PESNLKLASGFCPVEKLWQAGVNVAIG 307 Query: 299 PPLRPDPSTPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSV 358 +N+DL G E R + Sbjct: 308 ------------TDGAASNNDLDLLG----------------------------ETRTAA 327 Query: 359 IWEKGV--HSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISA 416 + K V + +D +R + + + N A+ L G + G AD+V +D G Sbjct: 328 LLAKAVYGQATALDAHRALRMATLNGARALGLERLIGSLEAGKAADLVAFDLSGLAQQPV 387 Query: 417 KTHHQAVNFNIFEGMVCHGVPLVTISRGKVVYEAGVFS 454 + + G C G+ + + G Sbjct: 388 YDPVSQLIYAS--GRDC---VRHVWVGGRQLLDDGRLL 420 >4LH8-A nrPDB Length = 469 Score = 52.0 bits (123), Expect = 6e-07, Method: Composition-based stats. Identities = 28/96 (29%), Positives = 45/96 (46%), Gaps = 11/96 (11%) Query: 7 LLIRG-GRVVNDDFSEV----ADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLP 61 +LIRG RV+ D E AD+L++ + A+G +L + R +D G + LP Sbjct: 15 ILIRGLTRVITFDDQERELEDADILIDGPKIVAVGKNLSD----RSVSRTIDGRGMIALP 70 Query: 62 GGIDTHTHMQFPFMGSRSIDDFHQGTKAALSGGTTM 97 G I++H H+ R+I + T A+ G Sbjct: 71 GLINSHQHLYE--GAMRAIPQLERVTMASWLEGVLT 104 >4F0R-A nrPDB Length = 447 Score = 51.6 bits (122), Expect = 8e-07, Method: Composition-based stats. Identities = 74/463 (15%), Positives = 132/463 (28%), Gaps = 109/463 (23%) Query: 25 VLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGIDTHTHMQF------------ 72 + + DG + A+ G L+ +++PG I+ H H Sbjct: 30 IAIRDGKIAAIIPAADAAG--LEADERLELPDHVLMPGLINLHGHSAMSLLRGLADDKAL 87 Query: 73 ---------PFMGSRSIDDF-HQGTKAA----LSGGTTMIIDFAIPQKGGS---LIEAFE 115 P G DDF G+ A + GGTT I D + L Sbjct: 88 MDWLTNYIWPTEGKHVHDDFVFDGSLLAMGEMIRGGTTTINDMYFYNAAVARAGLASGMR 147 Query: 116 TWRSWADPKVCCDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLEL 175 T+ + + +Y+ + D + + M Q G + +A Y V+D Sbjct: 148 TFVGCSILEFPTNYA-----SNADDYIAKGMAERSQFLGEDLLTFTLAPHAPYTVSDDTF 202 Query: 176 YEAFSRCKEIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAIT 235 + + ++ + H + E + G L R R Sbjct: 203 RKVVTLAEQEDMLI--HCHIHETADEVNNSVKEHGQR-----PLAR--------LQRLGL 247 Query: 236 IASAVNCPLYIVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHH 295 ++ + ++VH+ + A R G L T N + Sbjct: 248 LSPRLVA-AHMVHLNDAE----VELAARHG-----------LSTAHNPASNMKLASG--- 288 Query: 296 VMGPPLRPDPSTPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDR 355 + P + +A GTD N K D E R Sbjct: 289 -ISP-------VSKLMDAGVAVG----IGTDGAASN------NKLDMLA--------ETR 322 Query: 356 MSVIWEKGVHSGKMDENRF-----VAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKG 410 ++ + K G +D + + + N A+ + + G + VG AD++ D Sbjct: 323 LAALLAKV---GTLDPTSVPAAAAIRMATLNGARALGIADKVGSVKVGKQADLIALDLAQ 379 Query: 411 TRTISAKTHHQAVNFNIFEGMVCHGVPLVTISRGKVVYEAGVF 453 T A V + G +G+ + Sbjct: 380 LETAPAFDPISHVVYA--AGRE---QVSHVWVKGRALMRERKL 417 >4WHB-E nrPDB Length = 461 Score = 50.9 bits (120), Expect = 1e-06, Method: Composition-based stats. Identities = 62/460 (13%), Positives = 127/460 (27%), Gaps = 92/460 (20%) Query: 5 SRLLIRGGRVVNDDFSEV---ADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLP 61 S + I +++ V+VE +G P P G V+D + ++P Sbjct: 2 STIAITNVTLIDGLGGLPRPATTVIVEGDRFATVGPSDSTP--VPEGATVVDGNRRWMVP 59 Query: 62 GGIDTHTHMQFPFM--------------GSRSIDDFHQGTKAALSGGTTMIIDFAIPQKG 107 G ++ + H+ +M R ++ + + AL G T + D Sbjct: 60 GYVNGNVHLLDAWMFMAGPGTIEYLARWEGRYVEVIEEAAQLALRNGVTTVFD--THNAI 117 Query: 108 GSLIEAFETWRSWADPKVCCDYS-------------LHVAVTWWSDQVKEEMKILVQDKG 154 ++ A + + + H A + + + + + G Sbjct: 118 EPVLAARDRINAGISQGARIFAAGTIVGMGGPFSADFHFAGRTAATRTFVDRIDSMFEAG 177 Query: 155 VNSFKMFMAYKDLYMVTDLELYEAFSRCKEIGAIAQVHAENGDLIAEGAKKMLALGITGP 214 V + K++ L K H ++ + + + Sbjct: 178 VGHQLSLLPRKEVRARVRDYLSRGVDMLK---IAVSDH-----IVFTLVDRSVGFDRS-- 227 Query: 215 EGHELCRPEAVEAEATLRAITIASAVNCPLYIVHVMSK---SAAKVIADARRDGKVVYGE 271 RP RA P+ V + ++ ++ AD G+ Sbjct: 228 -YQTFSRPVLEVMVEEARA------AGVPVLTHSVSVEALDTSVELGADVLIHANYTLGQ 280 Query: 272 PIAASL---------------GTDGTHYWNKEWHHAAHHVMGPPLRPDPSTPDFLMN-LL 315 I L D ++ A + G P + +L Sbjct: 281 EIPNYLIDKIVASDSWAGLQTVHDQHRQGLEDVGSWAAALAGEPYATNERNLISANAKIL 340 Query: 316 ANDDLTTTGTDN-CTFNTCQKA-----LGKDDFTKIPNGVNGVEDRMSVIWEKGVHSGKM 369 N D D+ + ++ +G D F W + + M Sbjct: 341 LNTDAGCPSKDHLADLSPVEREDRPWTIGNDHFH----------------WTQSMVEKGM 384 Query: 370 DENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPK 409 ++ + N A+ + + G + G AD V+ D Sbjct: 385 SPLEAISAATINVARAYGKADQIGSVETGKLADFVLLDQD 424 >3MTW-A nrPDB Length = 403 Score = 50.5 bits (119), Expect = 2e-06, Method: Composition-based stats. Identities = 81/470 (17%), Positives = 132/470 (28%), Gaps = 101/470 (21%) Query: 3 APSRLL-IRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLP 61 + +RLL + G+ V++ V+V DG + ++G PAG +D G +LP Sbjct: 7 SAARLLDVASGKYVDNPL-----VIVTDGRITSIGKK---GDAVPAGATAVDLPGVTLLP 58 Query: 62 GGIDTHTHMQ-----FPFMGSRSIDDFHQGTKAA-----LSGGTTMIIDFAIPQ-KGGSL 110 G ID H H+ + D F + A L G T + + L Sbjct: 59 GLIDMHVHLDSLAEVGGYNSLEYSDRFWSVVQTANAKKTLEAGFTTVRNVGAADYDDVGL 118 Query: 111 IEAFETWRSWADPKVCCDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMV 170 EA + + ++ T F M K+ + Sbjct: 119 REAIDA--GYVPGPRIVTAAISFGATGGHCDS-------------TFFPPSMDQKNPFNS 163 Query: 171 T-DLELYEAFSRCKEIGAIAQVHAENGDLIAEG------AKKMLALGITGPEGHELCRPE 223 E +A K+ GA G + + G + E H Sbjct: 164 DSPDEARKAVRTLKKYGAQVIKICATGGVFSRGNEPGQQQLTYEEMKAVVDEAHMAGIKV 223 Query: 224 AVEAEATLRAITIASAVNCPLYIVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTH 283 A A I A I H + I A + G A D + Sbjct: 224 AAHAHGAS-GIREAVRAGVDT-IEHASLVDD-EGIKLAVQKG---------AYFSMDIYN 271 Query: 284 YWNKEWHHAAHHVMGPPLRPDPS----TPDFLMNLLANDDLTTTGTDNCTFNTCQKALGK 339 + + V+ LR D + L GTD + Sbjct: 272 TDYTQAEGKKNGVLEDNLRKDRDIGELQRENFRKALKAGVKMVYGTDAGIY--------- 322 Query: 340 DDFTKIPNGVNGVEDRMSVIWEKGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGS 399 P+G N + + V + + + + AA+ G++AVG Sbjct: 323 ------PHGDNAKQFAVMVRY-------GATPLQAIQSATLTAAEALGRSKDVGQVAVGR 369 Query: 400 DADIVIW--DPKGTRTISAKTHHQAVNFNIFEGMVCHGVPLVTISRGKVV 447 D++ DP + E P+ + G VV Sbjct: 370 YGDMIAVAGDP-------------LADVTTLE------KPVFVMKGGAVV 400 >6NBO-A nrPDB Length = 402 Score = 48.2 bits (113), Expect = 1e-05, Method: Composition-based stats. Identities = 24/71 (33%), Positives = 33/71 (46%), Gaps = 7/71 (9%) Query: 7 LLIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGIDT 66 LLIR R DD D+L+E + G L AP G + + AG + LPG ++ Sbjct: 12 LLIRNVRTGADDAL---DILIEGDRIARTGPSL----DAPPGCAIEEGAGAIALPGLVEG 64 Query: 67 HTHMQFPFMGS 77 HTH+ G Sbjct: 65 HTHLDKTHWGM 75 >1YRR-A nrPDB Length = 382 Score = 45.5 bits (106), Expect = 6e-05, Method: Composition-based stats. Identities = 75/432 (17%), Positives = 130/432 (30%), Gaps = 94/432 (21%) Query: 12 GRVVNDDFSEVAD--VLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGIDTH-- 67 GR+ + D V++ DG+++++ P P + G ++ PG ID Sbjct: 7 GRIFT-GHEFLDDHAVVIADGLIKSV----CPVAELPPEIEQRSLNGAILSPGFIDVQLN 61 Query: 68 ----THMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWADP 123 + S++ KA G T + I + + R + Sbjct: 62 GCGGVQFNDT-AEAVSVETLEIMQKANEKSGCTNYLPTLITTSDELMKQGVRVMREYLAK 120 Query: 124 KVCCDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEAFSRCK 183 LH+ W + + KG ++ F+ D +V L Sbjct: 121 HPNQALGLHLEGPWLN----------LVKKGTHN-PNFVRKPDAALVDFL---------- 159 Query: 184 EIGAIAQVHAENGDLI-----------AEGAKKMLALGITGPEGHELCRPEAVEAEATLR 232 EN D+I AE K+ GI GH EA+A R Sbjct: 160 ---------CENADVITKVTLAPEMVPAEVISKLANAGIVVSAGH--SNATLKEAKAGFR 208 Query: 233 A-ITIASAVNCPLYIVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHH 291 A IT A H+ + + G ++ I + DG H + Sbjct: 209 AGITFA---------THLYNAMPYITGREPGLAGAILDEADIYCGIIADGLHVDYANIRN 259 Query: 292 AAHHVMGPPLRPDPSTPDFLMNLLANDDLTTTGTDNCTFNTCQ-----KALGKDDFTKIP 346 A L+ D L T T N Q K + + + Sbjct: 260 AKR------LKGDKL------------CLVTDATAPAGANIEQFIFAGKTIYYRNGLCVD 301 Query: 347 NGVNGVEDRMSVI--WEKGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIV 404 +++I V + + + + + A+ + R G +A G A++ Sbjct: 302 ENGTLSGSSLTMIEGVRNLVEHCGIALDEVLRMATLYPARAIGVEKRLGTLAAGKVANLT 361 Query: 405 IWDPK--GTRTI 414 + P T+TI Sbjct: 362 AFTPDFKITKTI 373 >2OOF-A nrPDB Length = 416 Score = 45.1 bits (105), Expect = 7e-05, Method: Composition-based stats. Identities = 73/423 (17%), Positives = 124/423 (29%), Gaps = 79/423 (18%) Query: 25 VLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGIDTHTHMQFPFMGSRSIDDFH 84 + V +G + AL G PA + D GKLV PG ID HTH+ Sbjct: 32 LGVHEGRIHALVPMQDLKGPYPAHWQ--DMKGKLVTPGLIDCHTHL------------IF 77 Query: 85 QGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRS-----WADPKVCCDYSLHVAVTWWS 139 G++A +F + QKG E A D +A+ Sbjct: 78 AGSRAE---------EFELRQKGVPYAEIARKGGGIISTVRATRAASEDQLFELALPRVK 128 Query: 140 DQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEAFSRCKEIGAIAQVHAENGDLI 199 ++E GV + ++ K Y +T + + + +G + Sbjct: 129 SLIRE---------GVTTVEI----KSGYGLTLEDELKMLRVARRLGEALPI-------- 167 Query: 200 AEGAKKMLALGITGPEG--HELCRPEAVEAEATLRAITIASAVNCPLYIVHV--MSKSAA 255 +LA PE E + E A A ++ H+ Sbjct: 168 -RVKTTLLAAHAVPPEYRDDPDSWVETICQEIIPAAAEAGLADAVDVFCEHIGFSLAQTE 226 Query: 256 KVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMGPPLRPDPSTPDFLMNLL 315 +V A + G V G L G + + + + P+ + L Sbjct: 227 QVYLAADQYGLAVKG--HMDQLSNLGGSTLAANFGALSVDHL------EYLDPEGIQALA 278 Query: 316 ANDDLTTTGTDNCTFNTCQKALGKDDFTKI-----------PNGVNGVEDRMSVIWEKGV 364 + T F K K P V RM++ Sbjct: 279 HRGVVATLLPTAFYFLKETKLPPVVALRKAGVPMAVSSDINPGTAPIVSLRMAM--NMAC 336 Query: 365 HSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWD----PKGTRTISAKTHH 420 + +A + +AA+ + G++ VG AD ++W+ + + I Sbjct: 337 TLFGLTPVEAMAGVTRHAARALGEQEQLGQLRVGMLADFLVWNCGHPAELSYLIGVDQLV 396 Query: 421 QAV 423 V Sbjct: 397 SRV 399 >3GGM-A nrPDB Length = 81 Score = 44.7 bits (104), Expect = 1e-04, Method: Composition-based stats. Identities = 16/66 (24%), Positives = 33/66 (50%), Gaps = 3/66 (4%) Query: 7 LLIRGGRVVNDDFSEV--ADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGI 64 +++ G++ D S+ + + + DG++ A+G D L + +D K +PG Sbjct: 6 MILYNGKITTLDPSQPEVSAIAITDGLITAVGGDELLNSATEKTKK-IDLKRKRAIPGLN 64 Query: 65 DTHTHM 70 D+H H+ Sbjct: 65 DSHIHV 70 >3IGH-X nrPDB Length = 486 Score = 43.5 bits (101), Expect = 2e-04, Method: Composition-based stats. Identities = 18/81 (22%), Positives = 33/81 (40%), Gaps = 4/81 (4%) Query: 4 PSRLLIRGGRVVND--DFSEVADVLVEDGVVRALGHDLLPPG-GAPAGLRVLDAAGKLVL 60 + LI G + +V+ +++ G V G + +G ++D GK V+ Sbjct: 2 SLKALI-NGTIYTSFNPLKKVSGLVISHGKVIYAGDSEVAKKIVELSGGEIVDLKGKYVM 60 Query: 61 PGGIDTHTHMQFPFMGSRSID 81 P D+H H+ M +D Sbjct: 61 PAFFDSHLHLDELGMSLEMVD 81 >4LFY-A nrPDB Length = 372 Score = 43.1 bits (100), Expect = 3e-04, Method: Composition-based stats. Identities = 42/284 (14%), Positives = 78/284 (27%), Gaps = 44/284 (15%) Query: 65 DTHTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWADPK 124 D H H++ D + I + + + +R Sbjct: 37 DWHLHLRD--------GDMLAAVLPHTARQFGRAIVMPNLKPPVTTTAQAQAYRERILAA 88 Query: 125 VCCDYSLHVAVT-WWSDQVKEEMKILVQDKG-VNSFKMFMA----YKDLYMVTDLELYEA 178 + + +T + +D + ++ G V+ K++ A D + + + Sbjct: 89 LPAGMTFEPLMTLYLTDNTPPDEIRRARESGFVHGVKLYPAGATTNSDHGVTDLAKCAKT 148 Query: 179 FSRCKEIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIAS 238 +E G VH E +T R E R +T Sbjct: 149 LEAMQETGMPLLVHGE----------------VTDASIDLFDR----EKVFIDRVMTPLR 188 Query: 239 AVNCPLYIV--HVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAA--- 293 L +V H+ +K AA + DA + G I A Y Sbjct: 189 RDFPGLKVVFEHITTKDAADYVRDADAA-PGLLGATITAH----HLLYNRNALFVGGIRP 243 Query: 294 HHVMGPPLRPDPSTPDFLMNLLANDDLTTTGTDNCTFNTCQKAL 337 H+ P L+ + + + + GTD+ K Sbjct: 244 HYYCLPVLKRETHRVALVEAATSGNPRFFLGTDSAPHARDAKET 287 >3ICJ-A nrPDB Length = 534 Score = 42.8 bits (99), Expect = 3e-04, Method: Composition-based stats. Identities = 18/79 (22%), Positives = 32/79 (40%), Gaps = 4/79 (5%) Query: 6 RLLIRGGRVVND--DFSEVADVLVEDGVVRALGHD-LLPPGGAPAGLRVLDAAGKLVLPG 62 + LI G + +V+ +++ + V G AG ++D GK V+P Sbjct: 38 KALI-NGTIYTSFSPVKKVSGLVISNERVLYAGDSSTALRIAELAGGEIIDLKGKFVMPA 96 Query: 63 GIDTHTHMQFPFMGSRSID 81 D+H H+ M +D Sbjct: 97 FFDSHLHLDELGMSLEMVD 115 >2QS8-A nrPDB Length = 418 Score = 42.8 bits (99), Expect = 4e-04, Method: Composition-based stats. Identities = 80/478 (16%), Positives = 149/478 (31%), Gaps = 119/478 (24%) Query: 5 SRLLIRGGRVVN---DDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLP 61 S+ LI G++++ D ++++ ++ + + +D VLP Sbjct: 7 SKTLIHAGKLIDGKSDQVQSRISIVIDGNIISDIKKGFISSND---FEDYIDLRDHTVLP 63 Query: 62 GGIDTHTHM-QFPFMGSRSIDDFHQGTKAALS---------GGTTMIIDFAIPQKGG-SL 110 G +D H H Q +++ + +A L+ G T + SL Sbjct: 64 GLMDMHVHFGQEYQSKAQAPIKVEREMQAILATQHAYVTFKSGFTTVRQVGDSGLVAISL 123 Query: 111 IEAFETW-----RSWADPKVCCDYSLHVAVTWWSDQVKEEMKILVQDKGVNS--FKMFMA 163 +A + R +A K H T + + ++ V ++GV + ++++ A Sbjct: 124 RDAINSGKLAGPRIFAAGKTIATTGGHADPT--NGKAVDDYDYPVPEQGVVNGPYEVYAA 181 Query: 164 ----YKDLY---------------------MVTDLELYEAFSRCKEIGAIAQVHAENGDL 198 YKD T E+ S K+ G VHA + Sbjct: 182 VRQRYKDGADGIKITVTGGVLSVAKSGQNPQFTQEEVDAVVSAAKDYGMWVAVHAHGAE- 240 Query: 199 IAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAVNCPLYIVHVMSKSAAKVI 258 G K+ + G+ E ++ EA I N Y V + SA + + Sbjct: 241 ---GMKRAIKAGVDSIE-----HGTFMDLEAMDLMIE-----NGTYY---VPTISAGEFV 284 Query: 259 ADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMGPPLRPDPSTPDFLMNLLAND 318 A+ + + E +GP + D Sbjct: 285 AEKSK------------------IDNFFPEIVRPKAASVGPQIS------DTFRKAYEKG 320 Query: 319 DLTTTGTDNCTFNTCQK-ALGKDDFTKIPNGVNGVEDRMSVIWEKGVHSGKMDENRFVAV 377 GTD QK +F + VE+ M + + + Sbjct: 321 VKIAFGTD----AGVQKHGTNWKEFVYM------VENGMPAM-------------KAIQS 357 Query: 378 TSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTHHQAVNFNIFEGMVCHG 435 + AK+ + + G I G AD++ IS + V+ I +G++ G Sbjct: 358 ATMETAKLLRIEDKLGSIESGKLADLIAVKGNPIEDISV---LENVDVVIKDGLLYEG 412 >1R9X-A nrPDB Length = 430 Score = 42.8 bits (99), Expect = 4e-04, Method: Composition-based stats. Identities = 33/241 (13%), Positives = 77/241 (31%), Gaps = 46/241 (19%) Query: 1 MAAPSRLLIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVL 60 MA + I R+ ++ + ++DG + A+ G P LDA LV+ Sbjct: 4 MANNALQTIINARLPGEEGLWQ--IHLQDGKISAIDAQ---SGVMPITENSLDAEQGLVI 58 Query: 61 PGGIDTHTHMQFPFMGSRS----IDDFHQGT-----KAAL------------------SG 93 P ++ H H+ + +G + AL + Sbjct: 59 PPFVEPHIHLDTTQTAGQPNWNQSGTLFEGIERWAERKALLTHDDVKQRAWQTLKWQIAN 118 Query: 94 GTTMIIDFA-IPQKGGSLIEAFETWRSWADPKVCCD-----YSLHVAVTWWSDQVKEEMK 147 G + + + ++A + P D + +++ + + E Sbjct: 119 GIQHVRTHVDVSDATLTALKAMLEVKQEVAP--WIDLQIVAFPQEGILSYPNGEALLEEA 176 Query: 148 ILVQDKGVNSFKMFMAYKDLYMVTDLELYEAFSRCKEIGAIAQVHAENGDLIAEGAKKML 207 + + V + F ++ + L++ F+ ++ + VH D I + + + Sbjct: 177 LRLGADVVGAIPHFEFTREYGV---ESLHKTFALAQKYDRLIDVHC---DEIDDEQSRFV 230 Query: 208 A 208 Sbjct: 231 E 231 >2P9B-A nrPDB Length = 458 Score = 42.0 bits (97), Expect = 6e-04, Method: Composition-based stats. Identities = 17/64 (26%), Positives = 27/64 (42%), Gaps = 12/64 (18%) Query: 7 LLIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGIDT 66 ++R +V DG + + + PA LD GK+V+PG I+ Sbjct: 29 TILRNMTIVVG----------ADGRIEQVAPSIETS--IPAEYHYLDGTGKIVMPGLINA 76 Query: 67 HTHM 70 HTH+ Sbjct: 77 HTHL 80 Score = 28.9 bits (63), Expect = 5.1, Method: Composition-based stats. Identities = 15/92 (16%), Positives = 28/92 (30%), Gaps = 17/92 (18%) Query: 360 WEKGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTH 419 E V + + A I + G + VG AD+++ + Sbjct: 360 LELLVAYAGFSPAEALHAATAVNASILGVDAETGSLEVGKSADLLVLNA----------- 408 Query: 420 HQAVNFNIFEGMVCHGVPLVTISRGKVVYEAG 451 N + + P + I+ G V+ G Sbjct: 409 ------NPLDDLRALEHPALVIAAGHPVWRPG 434 >3LNP-A nrPDB Length = 468 Score = 41.6 bits (96), Expect = 8e-04, Method: Composition-based stats. Identities = 34/206 (16%), Positives = 72/206 (34%), Gaps = 50/206 (24%) Query: 25 VLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGIDTHTHM----------QFPF 74 +L++DG++ A+ LD ++++PG ++ H H P Sbjct: 53 LLIKDGIILAIEPQ---SSCQIPATETLDLGQQVLMPGWVNAHGHAAMSLFRGLADDLPL 109 Query: 75 MG----------SRSIDDFH--QGTKAALS----GGTTMIIDFAIPQKGGSLIEAFETWR 118 M ++ +D+ QGT+ A++ GTT D S A Sbjct: 110 MTWLQEHVWPAEAQHVDEHFVKQGTELAIAEMIQSGTTTFADMYF-YPQQSGEAALA--- 165 Query: 119 SWADPKVCCDYSLHVAVTWWSDQ-----VKEEMK-------ILVQDKGVNSFKMFMAYKD 166 A + C ++ + Q +++ ++ + ++G+ ++ Sbjct: 166 --AGIRAVC-FAPVLDFPTNYAQNADEYIRKAIECNDRFNNHPMNEQGLV--QIGFGPHA 220 Query: 167 LYMVTDLELYEAFSRCKEIGAIAQVH 192 Y V+D L E ++ Q+H Sbjct: 221 PYTVSDEPLKEITMLSDQLDMPVQIH 246 >4DZH-A nrPDB Length = 472 Score = 40.5 bits (93), Expect = 0.002, Method: Composition-based stats. Identities = 79/450 (17%), Positives = 131/450 (29%), Gaps = 109/450 (24%) Query: 3 APSRLLIRGGRVV----NDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKL 58 P LLI G VV + E V V +GV+ A+ A R + Sbjct: 12 EPCDLLIEAGYVVPIEPHAVVLEDHAVAVSNGVIVAVLP-TADARVRFAPARTVSRPDAA 70 Query: 59 VLPGGIDTHTHMQFPFMGSRSID--------DFHQGTKAALSG------GTTMIIDFAIP 104 ++PG ++ HTH + + D +AA+ G GTT+ I Sbjct: 71 LMPGLVNAHTHNPMTLLRGVADDLPLMVWLQQHIWPVEAAVIGPEFVADGTTLAIA---- 126 Query: 105 QKGGSLIEAFETWRSWADPKVCCDYSLHVAVTWWSDQVKEEMKILVQDKGVNSF--KMFM 162 E R C + + A + + + G + + + Sbjct: 127 ----------EMLR---GGTTCVNENYFFA---------DVQAAVYKQHGFRALVGAVII 164 Query: 163 AYKDLYMVTDLELYEAFSRCKEIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRP 222 + + +D E + A G+L + L P P Sbjct: 165 DFPTAWASSDDEYF----------------ARAGELHDQWRDDPLISTAFAPHA-----P 203 Query: 223 EAVEAEATLRAITIASAVNCPLYI-VHVMSKSAAKVIADARRDGK---VVYGEPIAASLG 278 V R +A ++ P+++ H ++ A +A + G + Sbjct: 204 YTVNDANFERVRMLADQLDMPVHLHTHETAQEVADSVAQYGQRPLARLDRLGLVNDRLIA 263 Query: 279 TDGTHYWNKEWHHAAHHVMGPPLRPDPSTPDFLMNLLANDDLTTTGTDNCTFNTCQKALG 338 T E H A + P+ + + C Q+A Sbjct: 264 VHMTQLTEAEIHLCAERGVSVVHCPESNLK--------------LASGFCPACALQRAS- 308 Query: 339 KDDFTKIPNGVNGV----------EDRMSVIWEKGVHSGKMDENRFVAVTSTNAAKI--- 385 + G +G E+R + I K V + D A T+ AA + Sbjct: 309 ----VNLAIGTDGCASNNDLDMFSENRTAAILAKAVAN---DATALDAATTLRAATLGGA 361 Query: 386 --FNLYPRKGRIAVGSDADIVIWDPKGTRT 413 R G I VG AD+V D T Sbjct: 362 RALGFGDRIGSIEVGKQADLVCVDLSALET 391 >6CTY-A nrPDB Length = 372 Score = 40.5 bits (93), Expect = 0.002, Method: Composition-based stats. Identities = 44/284 (15%), Positives = 89/284 (31%), Gaps = 49/284 (17%) Query: 65 DTHTHMQFPFMGSR----SIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSW 120 D H H++ M S + + F + I + + + + +R Sbjct: 39 DWHIHLRDDEMLSTVLPYTSEVFARA------------IVMPNLAQPITTVASAIAYRER 86 Query: 121 ADPKVCCDYSLHVAVTWWSDQVKEEMKILVQ-DKGV-NSFKMF---MAYKDLYMVTDL-E 174 V + +T + + ++ ++GV + K++ + V+D+ Sbjct: 87 ILAAVPAGHKFTPLMTCYLTNSLDAKELTTGFEQGVFTAAKLYPANATTNSTHGVSDIPA 146 Query: 175 LYEAFSRCKEIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAI 234 +Y F + ++IG +H G++ + E R + E + Sbjct: 147 IYPLFEQMQKIGMPLLIH---GEVTDAAVDIFDREARFIDQILEPIRQKFPELKIVFE-- 201 Query: 235 TIASAVNCPLYIVHVMSKSAAK-VIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAA 293 H+ +K AA V+A R G V L + H Sbjct: 202 -------------HITTKDAADYVLAGNRFLGATVT----PQHLMFNRNHML---VGGIR 241 Query: 294 HHVMGPPLRPDPSTPDFLMNLLAND-DLTTTGTDNCTFNTCQKA 336 H+ P+ + L +A+ D GTD+ +K Sbjct: 242 PHLFCLPILKRSTHQQALRAAVASGSDRFFLGTDSAPHAKHRKE 285 >3JZE-A nrPDB Length = 372 Score = 40.1 bits (92), Expect = 0.003, Method: Composition-based stats. Identities = 39/286 (13%), Positives = 84/286 (29%), Gaps = 51/286 (17%) Query: 65 DTHTHMQFPFMGSRSID-DFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWADP 123 D H H++ M + +A I + ++A +R Sbjct: 39 DWHVHLRDGDMLKTVVPYTSEIYGRA---------IVMPNLASPITTVDAAIAYRQRILD 89 Query: 124 KVCCDYSLHVAVT-WWSDQVK-EEMKILVQDKGVNSFKMFMAYKDL----YMVTDLELYE 177 V + +T + +D + +E++ + + K++ A + + + Sbjct: 90 AVPAGHDFTPLMTCYLTDSLDADELERGFHEGVFTAAKLYPANATTNSSHGVTSVDAIMP 149 Query: 178 AFSRCKEIGAIAQVHAE----NGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRA 233 R +++G VH E + D+ A+ + + P Sbjct: 150 VLERMEKLGIPLLVHGEVTHADVDIFDREARFI----------DTVMEP----------- 188 Query: 234 ITIASAVNCPLYIVHVMSKSAAKVIADARRDGKVVYGEPI-AASLGTDGTHYWNKEWHHA 292 + H+ +K AA+ + D G I L + + Sbjct: 189 -LRQRLTALKVVFEHITTKDAAQYVRD----GNDYLAATITPQHLMFNR---NDMLVGGI 240 Query: 293 AHHVMGPPLRPDPSTPDFLMNLLANDDLTT-TGTDNCTFNTCQKAL 337 H+ P+ L L+A+ GTD+ + +K Sbjct: 241 RPHLYCLPILKRNIHQQALRELVASGFTRAFLGTDSAPHSRHRKET 286 >2OOD-A nrPDB Length = 475 Score = 37.8 bits (86), Expect = 0.012, Method: Composition-based stats. Identities = 14/46 (30%), Positives = 25/46 (54%), Gaps = 1/46 (2%) Query: 25 VLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGIDTHTHM 70 ++V DGV++A G P G+ + ++++PG ID H H+ Sbjct: 38 MVVTDGVIKAFGPYEKIAAAHP-GVEITHIKDRIIVPGFIDGHIHL 82 >3MDW-A nrPDB Length = 453 Score = 36.6 bits (83), Expect = 0.027, Method: Composition-based stats. Identities = 14/69 (20%), Positives = 25/69 (36%), Gaps = 3/69 (4%) Query: 393 GRIAVGSDADIVIWDPKGTRTISAKTHHQAVNFNIFEGMVCHGVPLVTISRGKVVYEAGV 452 G +AVG AD+++ D SA+ + +F G + G+ V G Sbjct: 377 GSLAVGRRADLLVLDGNDPYLASAEGDALLNRW-LFAGGDRQ--VRDVMVAGRWVVRDGR 433 Query: 453 FSVTAGDGK 461 + + Sbjct: 434 HAGEERSAR 442 >2I9U-A nrPDB Length = 439 Score = 36.2 bits (82), Expect = 0.038, Method: Composition-based stats. Identities = 11/45 (24%), Positives = 22/45 (48%), Gaps = 3/45 (6%) Query: 25 VLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGIDTHTH 69 ++V DG + ++ +L G ++D +++PG D H H Sbjct: 34 IVVIDGKIASVSSNL---PDKYKGNPIIDFRNNIIIPGMNDLHAH 75 >2PAJ-A nrPDB Length = 492 Score = 35.8 bits (81), Expect = 0.051, Method: Composition-based stats. Identities = 16/78 (20%), Positives = 28/78 (35%), Gaps = 4/78 (5%) Query: 7 LLIRGGRVVNDDFSEVAD--VLVEDGVVRALGHDLLPPGG--APAGLRVLDAAGKLVLPG 62 LIR + AD V +R +G + G G ++DA ++ P Sbjct: 12 TLIRNAAAIMTGGRGTADDPSRVPGPDIRIVGDTIDAIGALAPRPGETIVDATDCVIYPA 71 Query: 63 GIDTHTHMQFPFMGSRSI 80 ++TH H+ + Sbjct: 72 WVNTHHHLFQSLLKGEPA 89 >2WJF-A nrPDB Length = 247 Score = 35.4 bits (80), Expect = 0.066, Method: Composition-based stats. Identities = 27/158 (17%), Positives = 55/158 (34%), Gaps = 14/158 (8%) Query: 62 GGIDTHTHMQ-FPFMGSRSIDDFHQGTKAALSGGTTMIIDFA------IPQKGGSLIEAF 114 G ID H+H+ G +S ++ + G I+ + + E F Sbjct: 4 GMIDIHSHIVFDVDDGPKSREESKALLAESYRQGVRTIVSTSHRRKGMFETPEEKIAENF 63 Query: 115 ETWRSWADPKVCCDYSLHVAVTWWSDQVKEEMKILVQDKGVNSF-KMFMAYKDLYMVTDL 173 R A + A +++ V ++++ K + + A + M T Sbjct: 64 LQVREIAKEVASDLVIAYGAEIYYTPDVLDKLE----KKRIPTLNDSRYALIEFSMNTPY 119 Query: 174 -ELYEAFSRCKEIG-AIAQVHAENGDLIAEGAKKMLAL 209 +++ A S+ +G H E D + K++ L Sbjct: 120 RDIHSALSKILMLGITPVIAHIERYDALENNEKRVREL 157 >6FV3-A nrPDB Length = 401 Score = 33.9 bits (76), Expect = 0.20, Method: Composition-based stats. Identities = 25/136 (18%), Positives = 43/136 (31%), Gaps = 12/136 (8%) Query: 5 SRLLIRGGRVVNDDFS-EVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGG 63 S +L+ V+ + + V A+G P V+PG Sbjct: 15 SHMLLTADTVLTGTELLRPGWLEIASDRVVAVGAGAPPAQADRNL------GAATVVPGF 68 Query: 64 IDTHTHMQFPFMGSRSIDDFHQGTKAAL--SGGTTMIIDFAIPQKGGSLIEAFETWRSWA 121 +DTH H S + DD AL + G+T ++ + L+ Sbjct: 69 VDTHLHGGGGGNFSAATDD-ETARAVALHRAHGSTTLVASLVTAGPEDLLRQVSGLARQV 127 Query: 122 DPKVCCDYSLHVAVTW 137 + D +H+ W Sbjct: 128 RAGL-ID-GIHLEGPW 141 >5YDJ-A nrPDB Length = 737 Score = 32.7 bits (73), Expect = 0.37, Method: Composition-based stats. Identities = 20/80 (25%), Positives = 29/80 (36%), Gaps = 10/80 (12%) Query: 189 AQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAVNCPLYIVH 248 +H + + +L G + R EATLRA+ +A AV CP H Sbjct: 366 VSLHLLSALSRDLFQRAILQSGSPTAPWALVSR-----EEATLRALRLAEAVGCP----H 416 Query: 249 VMSKSAAKVIADARRDGKVV 268 SK + + R V Sbjct: 417 EPSKLS-DAVECLRGKDPHV 435 >5YDI-A nrPDB Length = 553 Score = 32.7 bits (73), Expect = 0.37, Method: Composition-based stats. Identities = 20/80 (25%), Positives = 29/80 (36%), Gaps = 10/80 (12%) Query: 189 AQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAVNCPLYIVH 248 +H + + +L G + R EATLRA+ +A AV CP H Sbjct: 205 VSLHLLSALSRDLFQRAILQSGSPTAPWALVSR-----EEATLRALRLAEAVGCP----H 255 Query: 249 VMSKSAAKVIADARRDGKVV 268 SK + + R V Sbjct: 256 EPSKLS-DAVECLRGKDPHV 274 >6NRZ-A nrPDB Length = 534 Score = 32.7 bits (73), Expect = 0.39, Method: Composition-based stats. Identities = 25/134 (18%), Positives = 47/134 (35%), Gaps = 14/134 (10%) Query: 105 QKGGSLIEAFETWRSWADPKVCCDYSL-HVAVTWWSDQVKEEMKILVQDKGVNSFKM--- 160 ++IEA+ + + D C + + ++ + + + + L V FK Sbjct: 288 NPEFTMIEAYAAYWDYNDVMKCVENLVEYIVRALNNGETQVQYSHLKSGPQVVDFKAPWI 347 Query: 161 FMAYK---------DLYMVTDLELYEAFSRCKEIGAIAQVHAENGDLIAEGAKKMLALGI 211 M K D+ + D EL + + VHA G+LIA +++ + Sbjct: 348 RMTMKESISVYGGVDVDLHADHELRKILETQTSLPEKTYVHASRGELIALLFDELVCDKL 407 Query: 212 TGPEGHELCRPEAV 225 P H P Sbjct: 408 IAPH-HITDHPLET 420 >5JCN-A nrPDB Length = 451 Score = 32.4 bits (72), Expect = 0.47, Method: Composition-based stats. Identities = 22/107 (20%), Positives = 35/107 (32%), Gaps = 21/107 (19%) Query: 392 KGRIAVGSDAD----IVIWDPKGTRTISAKTHHQAVNFNIFEGMVCHGVPLVTISRGKVV 447 KG +AVG DAD + + K + A G PL T+ +G+V Sbjct: 241 KGTVAVGFDADANGDVTAVNLKNGSVLEADIVVVG----------VGGRPLTTLFKGQVA 290 Query: 448 YEAGVFSVTAGDGKFIP-------RKPFAEYIYKRIKQRDRTCTPTP 487 E G A +P F +Y +++ + Sbjct: 291 EEKGGIKTDAFFETSVPGVYAVGDVATFPMKMYNELRRVEHVDHARK 337 >1S69-A nrPDB Length = 124 Score = 32.0 bits (71), Expect = 0.58, Method: Composition-based stats. Identities = 18/88 (20%), Positives = 35/88 (39%), Gaps = 1/88 (1%) Query: 114 FETWRSWADPKVCCDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDL 173 + + A K Y+ + ++E K LV++ G+N F A + + T Sbjct: 38 VDMAKQRAHQKAFLTYAFGGTDKYDGRYMREAHKELVENHGLNGE-HFDAVAEDLLATLK 96 Query: 174 ELYEAFSRCKEIGAIAQVHAENGDLIAE 201 E+ E+ A+A A D++ + Sbjct: 97 EMGVPEDLIAEVAAVAGAPAHKRDVLNQ 124 >2QIW-A nrPDB Length = 255 Score = 31.6 bits (70), Expect = 0.86, Method: Composition-based stats. Identities = 22/151 (14%), Positives = 44/151 (29%), Gaps = 22/151 (14%) Query: 146 MKILVQDKGVNSFKMFMAYKDLYMVTDLELYEAFSRCKEIGAIA--QVHAENGDLIAEGA 203 M ++ + S + + + Y ++ +L +G VH+E G + E Sbjct: 69 MAVVKKITSAVSIPVSVDVESGYGLSPADLIAQILEAGAVGINVEDVVHSE-GKRVREAQ 127 Query: 204 KKM-----------------LALGITGPEGHELCRPEAVEAEATLRAITIASAVNCP-LY 245 + + G T E EA R I + +Y Sbjct: 128 EHADYIAAARQAADVAGVDVVINGRTDAVKLGADVFEDPMVEAIKR-IKLMEQAGARSVY 186 Query: 246 IVHVMSKSAAKVIADARRDGKVVYGEPIAAS 276 V + + + + DA + P+ Sbjct: 187 PVGLSTAEQVERLVDAVSVPVNITAHPVDGH 217 >3RZZ-A nrPDB Length = 446 Score = 30.8 bits (68), Expect = 1.5, Method: Composition-based stats. Identities = 31/147 (21%), Positives = 45/147 (30%), Gaps = 21/147 (14%) Query: 84 HQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWADPKVC--------CDYSLHVAV 135 H T AA + G L A + S V DY + + Sbjct: 247 HTRTSAAEAAGV----------PPADLEAALRSPASETGLTVLRTLGRALGFDYRVLLPA 296 Query: 136 TWWSDQVKEEMKILVQ-DKGVNSFKMFMAYKDLYMVTDLELYEAFSR--CKEIGAIAQVH 192 D V + + + +F + A +L +F R GA H Sbjct: 297 DDQHDGVGKTWTTIEDSRRSRRTFGTYEAASMASAAHLPDLVGSFLRVDADGRGADLIDH 356 Query: 193 AENGDLIAEGAKKMLALGITGPEGHEL 219 AEN ++ EG + G GP EL Sbjct: 357 AENHYVVTEGRLTLEWDGPDGPASVEL 383 >6ERI-Ad nrPDB Length = 72 Score = 30.1 bits (66), Expect = 2.2, Method: Composition-based stats. Identities = 11/45 (24%), Positives = 22/45 (48%), Gaps = 2/45 (4%) Query: 458 GDGKFIPRKPFAEYIY--KRIKQRDRTCTPTPVERAPYKGEVATL 500 G GK + R+ +++ K K+++R V+R+ Y + L Sbjct: 19 GKGKIVRRRAGKQHLLAKKNTKRKNRLSKLIQVDRSDYDNVIGAL 63 >5MLC-5 nrPDB Length = 159 Score = 30.1 bits (66), Expect = 2.2, Method: Composition-based stats. Identities = 11/45 (24%), Positives = 22/45 (48%), Gaps = 2/45 (4%) Query: 458 GDGKFIPRKPFAEYIY--KRIKQRDRTCTPTPVERAPYKGEVATL 500 G GK + R+ +++ K K+++R V+R+ Y + L Sbjct: 106 GKGKIVRRRAGKQHLLAKKNTKRKNRLSKLIQVDRSDYDNVIGAL 150 >1Z72-A nrPDB Length = 225 Score = 30.1 bits (66), Expect = 2.8, Method: Composition-based stats. Identities = 25/145 (17%), Positives = 50/145 (34%), Gaps = 10/145 (6%) Query: 105 QKGGSLIEAFETWRSWADPKVCCDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAY 164 Q G ++ E S D + ++ + + + K L+QD F F++ Sbjct: 12 QPGLTVGE--LLKSSQKDWQAAINHRFVKELFAGTIENKVLKDYLIQDYHF--FDAFLSM 67 Query: 165 KDLYMVTDLELYEAFSRCKEIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEA 224 + +L K++G + E+G K L + + E+ Sbjct: 68 LGACVAHADKLESKLRFAKQLGFLEAD--EDG----YFQKAFKELKVAENDYLEVTLHPV 121 Query: 225 VEAEATLRAITIASAVNCPLYIVHV 249 +A L +AS+ L ++ V Sbjct: 122 TKAFQDLMYSAVASSDYAHLLVMLV 146 >2QI2-A nrPDB Length = 347 Score = 29.7 bits (65), Expect = 3.4, Method: Composition-based stats. Identities = 13/62 (20%), Positives = 23/62 (37%) Query: 193 AENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAVNCPLYIVHVMSK 252 A D+ G + + G + E E R+++IA V ++IV V + Sbjct: 260 AVKKDMGVYGRDQTESALQMGALSDLIITDEMFRTEDGRRSLSIAQTVGTRIHIVSVSND 319 Query: 253 SA 254 Sbjct: 320 PG 321 >4WVX-A nrPDB Length = 326 Score = 29.7 bits (65), Expect = 3.4, Method: Composition-based stats. Identities = 18/88 (20%), Positives = 33/88 (37%), Gaps = 15/88 (17%) Query: 145 EMKILVQDKGVNSFKMFMAYKDLYMVTDLELY--EAFSRCKEIGAIAQVHAENGDLIAEG 202 E+ + D G+ + + +A + +++ A KE GA+ H + G + E Sbjct: 129 ELTEGIADTGIKAGVIKLASSKGRITEYEKMFFRAAARAQKETGAVIITHTQEGTMGPEQ 188 Query: 203 AKKMLAL-------------GITGPEGH 217 A +L G T P+ H Sbjct: 189 AAYLLEHGADPKKIVIGHMCGNTDPDYH 216 >2OI8-A nrPDB Length = 216 Score = 29.7 bits (65), Expect = 3.5, Method: Composition-based stats. Identities = 20/77 (25%), Positives = 30/77 (38%), Gaps = 13/77 (16%) Query: 70 MQFPFMGSRSIDDFHQGTKAALSGGTTM--IIDFAIPQKGGSLIE-----AFETWRSWAD 122 P G R+ DD T+ A TM I+D + +T R WA Sbjct: 111 FGTPVPGYRAPDDI---TEIAAE---TMAVIVDACAALPPSDGTDGAFDAHLDTHRQWAG 164 Query: 123 PKVCCDYSLHVAVTWWS 139 + +LH A+++WS Sbjct: 165 DRPAPSSALHRALSFWS 181 >2YFK-A nrPDB Length = 418 Score = 29.3 bits (64), Expect = 4.7, Method: Composition-based stats. Identities = 22/121 (18%), Positives = 35/121 (28%), Gaps = 17/121 (14%) Query: 345 IPNGVNGVEDRMSVIWEKGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVG-SDADI 403 +P G+ G+ R+ + G V NAA+ + + +A DAD+ Sbjct: 207 VPQGIVGLMTRLGMDVVLAHPEGYEIMPEVEEVAKKNAAEFGGNFTKTNSMAEAFKDADV 266 Query: 404 VI---WDPKGTRT-------------ISAKTHHQAVNFNIFEGMVCHGVPLVTISRGKVV 447 V W P I + C + T GK + Sbjct: 267 VYPKSWAPFAAMEKRTELYGNGDQAGIDQLEQELLSQNKKHKDWECTEELMKTTKDGKAL 326 Query: 448 Y 448 Y Sbjct: 327 Y 327 >5WLC-LV nrPDB Length = 707 Score = 28.9 bits (63), Expect = 5.1, Method: Composition-based stats. Identities = 13/72 (18%), Positives = 29/72 (40%), Gaps = 4/72 (5%) Query: 359 IWEKGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIV-IWDPKGTRTISAK 417 ++ + G+ N F T ++ G +A G++ ++V WDP+ +S Sbjct: 162 LYRLNLEKGRF-LNPF--KLDTEGVNHVSINEVNGLLAAGTETNVVEFWDPRSRSRVSKL 218 Query: 418 THHQAVNFNIFE 429 ++ F+ Sbjct: 219 YLENNIDNRPFQ 230 >1AOS-A nrPDB Length = 464 Score = 28.5 bits (62), Expect = 8.2, Method: Composition-based stats. Identities = 28/139 (20%), Positives = 49/139 (35%), Gaps = 10/139 (7%) Query: 110 LIEAFETWRSWADPKVCCDYSLHVAVTWWSDQVKEEMKILVQDKGVNSF--KMFMAYKDL 167 L +A+ T S K D SL + + +L+ KG+ S K K+ Sbjct: 273 LSDAYSTGSSLMPQKKNPD-SLELIRSKAGRVFGRCAGLLMTLKGLPSTYNKDLQEDKEA 331 Query: 168 YMVTDLELYEAFSRCKEIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCR--PEAV 225 + + + Q+H EN + + MLA T + + + P Sbjct: 332 VFEVSDTMSAVLQVATGVISTLQIHQEN--MGQALSPDMLA---TDLAYYLVRKGMPFRQ 386 Query: 226 EAEATLRAITIASAVNCPL 244 EA+ +A+ +A L Sbjct: 387 AHEASGKAVFMAETKGVAL 405 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.306 0.132 0.347 Lambda K H 0.267 0.0408 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 19,462,366 Number of Sequences: 36641 Number of extensions: 796357 Number of successful extensions: 2664 Number of sequences better than 10.0: 101 Number of HSP's better than 10.0 without gapping: 124 Number of HSP's successfully gapped in prelim test: 50 Number of HSP's that attempted gapping in prelim test: 2242 Number of HSP's gapped (non-prelim): 240 length of query: 519 length of database: 10,336,785 effective HSP length: 101 effective length of query: 418 effective length of database: 6,636,044 effective search space: 2773866392 effective search space used: 2773866392 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.0 bits) S2: 61 (28.1 bits)