BLASTP 2.2.23 [Feb-03-2010]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment: Altschul, Stephen F.,
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Reference for composition-based statistics starting in round 2:
Schaffer, Alejandro A., L. Aravind, Thomas L. Madden,
Sergei Shavirin, John L. Spouge, Yuri I. Wolf,
Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005.
Query= Q14117
(519 letters)
Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta
36,641 sequences; 10,336,785 total letters
Searching..................................................done
Results from round 1
Score E
Sequences producing significant alignments: (bits) Value
2VR2-A nrPDB 1078 0.0
4LCQ-A nrPDB 785 0.0
5YZA-A nrPDB 649 0.0
1KCX-A nrPDB 646 0.0
4CNT-A nrPDB 645 0.0
4CNS-A nrPDB 640 0.0
4B90-A nrPDB 615 e-176
2FTW-A nrPDB 614 e-176
5NKS-A nrPDB 613 e-176
4B91-A nrPDB 604 e-173
6AJD-A nrPDB 491 e-139
3DC8-A nrPDB 464 e-131
4TQT-A nrPDB 451 e-127
1YNY-A nrPDB 370 e-103
3SFW-A nrPDB 368 e-102
1K1D-A nrPDB 351 6e-97
1GKQ-A nrPDB 344 5e-95
1NFG-A nrPDB 291 5e-79
2FTY-A nrPDB 211 4e-55
1GKR-A nrPDB 171 6e-43
3E74-A nrPDB 133 2e-31
3HM7-A nrPDB 124 9e-29
3GRI-A nrPDB 105 6e-23
3MPG-A nrPDB 101 7e-22
2Z00-A nrPDB 73 3e-13
1XRT-A nrPDB 67 3e-11
2GWN-A nrPDB 54 2e-07
6HG1-A nrPDB 45 1e-04
2VUN-A nrPDB 41 0.001
1FWC-C nrPDB 40 0.002
4V1Y-A nrPDB 39 0.005
2VHL-A nrPDB 37 0.014
5T5I-A nrPDB 37 0.028
1RK6-A nrPDB 35 0.053
3MKV-A nrPDB 35 0.087
3OOQ-A nrPDB 35 0.098
2BB0-A nrPDB 34 0.13
2OOF-A nrPDB 34 0.17
3K7I-B nrPDB 34 0.18
6ASO-A nrPDB 33 0.22
6NBO-A nrPDB 33 0.33
2PUZ-A nrPDB 33 0.34
2Z1T-A nrPDB 33 0.34
2AQV-A nrPDB 33 0.36
3T8L-A nrPDB 33 0.37
3GIQ-A nrPDB 33 0.42
4CQD-A nrPDB 32 0.73
2P9B-A nrPDB 32 0.76
3HPA-A nrPDB 32 0.87
4CEX-C nrPDB 31 1.0
3MTW-A nrPDB 31 1.2
2OGJ-A nrPDB 30 2.1
2Y7H-A nrPDB 30 2.5
3IGH-X nrPDB 30 3.1
4LH8-A nrPDB 30 3.2
3N2C-A nrPDB 30 3.4
4Z42-C nrPDB 30 3.5
3GGM-A nrPDB 30 3.5
3QGK-C nrPDB 29 4.0
5YGQ-A nrPDB 29 4.5
1U83-A nrPDB 29 4.8
1YQC-A nrPDB 29 5.2
1AK1-A nrPDB 29 5.4
2PLM-A nrPDB 29 6.4
3ICJ-A nrPDB 28 7.4
2GBX-B nrPDB 28 8.3
2OOD-A nrPDB 28 8.9
>2VR2-A nrPDB
Length = 541
Score = 1078 bits (2787), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 519/519 (100%), Positives = 519/519 (100%)
Query: 1 MAAPSRLLIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVL 60
MAAPSRLLIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVL
Sbjct: 23 MAAPSRLLIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVL 82
Query: 61 PGGIDTHTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSW 120
PGGIDTHTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSW
Sbjct: 83 PGGIDTHTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSW 142
Query: 121 ADPKVCCDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEAFS 180
ADPKVCCDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEAFS
Sbjct: 143 ADPKVCCDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEAFS 202
Query: 181 RCKEIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAV 240
RCKEIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAV
Sbjct: 203 RCKEIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAV 262
Query: 241 NCPLYIVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMGPP 300
NCPLYIVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMGPP
Sbjct: 263 NCPLYIVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMGPP 322
Query: 301 LRPDPSTPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIW 360
LRPDPSTPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIW
Sbjct: 323 LRPDPSTPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIW 382
Query: 361 EKGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTHH 420
EKGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTHH
Sbjct: 383 EKGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTHH 442
Query: 421 QAVNFNIFEGMVCHGVPLVTISRGKVVYEAGVFSVTAGDGKFIPRKPFAEYIYKRIKQRD 480
QAVNFNIFEGMVCHGVPLVTISRGKVVYEAGVFSVTAGDGKFIPRKPFAEYIYKRIKQRD
Sbjct: 443 QAVNFNIFEGMVCHGVPLVTISRGKVVYEAGVFSVTAGDGKFIPRKPFAEYIYKRIKQRD 502
Query: 481 RTCTPTPVERAPYKGEVATLKSRVTKEDATAGTRKQAHP 519
RTCTPTPVERAPYKGEVATLKSRVTKEDATAGTRKQAHP
Sbjct: 503 RTCTPTPVERAPYKGEVATLKSRVTKEDATAGTRKQAHP 541
>4LCQ-A nrPDB
Length = 520
Score = 785 bits (2026), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 368/500 (73%), Positives = 428/500 (85%), Gaps = 4/500 (0%)
Query: 1 MAAPSRLLIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVL 60
MA +LI+GG+VVN+D S +DV + G + +G DL P GA RV+DA +LV+
Sbjct: 21 MAEAGEILIKGGKVVNEDCSFFSDVHIRGGKIVEVGPDLRVPPGA----RVIDATDRLVI 76
Query: 61 PGGIDTHTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSW 120
PGGIDTHTHM+ FMG+R++DDFH GTKAAL+GGTTMI+DF + QKG SL+EA++ WR
Sbjct: 77 PGGIDTHTHMELAFMGTRAVDDFHIGTKAALAGGTTMILDFVMTQKGQSLLEAYDLWRKT 136
Query: 121 ADPKVCCDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEAFS 180
ADPKVCCDYSLHVAVTWWSD+VK+EM+ L Q++GVNSFKMFMAYK L+M+ D ELY FS
Sbjct: 137 ADPKVCCDYSLHVAVTWWSDEVKDEMRTLAQERGVNSFKMFMAYKGLFMLRDDELYAVFS 196
Query: 181 RCKEIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAV 240
CKE+GAIAQVHAENGDLIAEGAKKML+LGITGPEGHELCRPEAVEAEAT RAITIASAV
Sbjct: 197 HCKEVGAIAQVHAENGDLIAEGAKKMLSLGITGPEGHELCRPEAVEAEATQRAITIASAV 256
Query: 241 NCPLYIVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMGPP 300
NCPLY+VHVMSKSAA V++ AR+DG+VV+GEPIAASLGTDGT+YW+K+W HAA +VMGPP
Sbjct: 257 NCPLYVVHVMSKSAADVVSKARKDGRVVFGEPIAASLGTDGTNYWHKDWAHAAQYVMGPP 316
Query: 301 LRPDPSTPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIW 360
LRPDPSTP +LM+LLANDDLT TGTDNCTF+ CQKALGKDDFT+IPNGVNGVEDRMSVIW
Sbjct: 317 LRPDPSTPGYLMDLLANDDLTLTGTDNCTFSRCQKALGKDDFTRIPNGVNGVEDRMSVIW 376
Query: 361 EKGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTHH 420
EKGVHSGKMDENRFVAVTS+NAAKIFN YP+KGRIA SDAD+VIWDPK TR ISA+THH
Sbjct: 377 EKGVHSGKMDENRFVAVTSSNAAKIFNFYPQKGRIAKDSDADVVIWDPKTTRKISAQTHH 436
Query: 421 QAVNFNIFEGMVCHGVPLVTISRGKVVYEAGVFSVTAGDGKFIPRKPFAEYIYKRIKQRD 480
QAV++NIFEGM CHGVP+VT+SRG+VVYE G V+ G G+FI R+PF+E++YKRI+QRD
Sbjct: 437 QAVDYNIFEGMECHGVPVVTVSRGRVVYEEGRLKVSPGQGRFIHRQPFSEFVYKRIRQRD 496
Query: 481 RTCTPTPVERAPYKGEVATL 500
P V R PY GEV L
Sbjct: 497 EVGKPAVVIREPYAGEVVAL 516
>5YZA-A nrPDB
Length = 525
Score = 649 bits (1674), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 308/514 (59%), Positives = 385/514 (74%), Gaps = 6/514 (1%)
Query: 6 RLLIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGID 65
RLLI+GG++VNDD S AD+ +EDG+++ +G +L+ PGG ++ ++A ++V+PGGID
Sbjct: 16 RLLIKGGKIVNDDQSFYADIYMEDGLIKQIGENLIVPGG----VKTIEAHSRMVIPGGID 71
Query: 66 THTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWADPKV 125
HT Q P G S DDF QGTKAAL+GGTTMIID +P+ G SL+ AF+ WR WAD K
Sbjct: 72 VHTRFQMPDQGMTSADDFFQGTKAALAGGTTMIIDHVVPEPGTSLLAAFDQWREWADSKS 131
Query: 126 CCDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEAFSRCKEI 185
CCDYSLHV ++ W ++EEM+ LV+D GVNSF ++MA+KD + +TD ++YE S ++I
Sbjct: 132 CCDYSLHVDISEWHKGIQEEMEALVKDHGVNSFLVYMAFKDRFQLTDCQIYEVLSVIRDI 191
Query: 186 GAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAVNCPLY 245
GAIAQVHAENGD+IAE +++L LGITGPEGH L RPE VEAEA RAITIA+ NCPLY
Sbjct: 192 GAIAQVHAENGDIIAEEQQRILDLGITGPEGHVLSRPEEVEAEAVNRAITIANQTNCPLY 251
Query: 246 IVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMGPPLRPDP 305
I VMSKS+A+VIA AR+ G VVYGEPI ASLGTDG+HYW+K W AA V PPL PDP
Sbjct: 252 ITKVMSKSSAEVIAQARKKGTVVYGEPITASLGTDGSHYWSKNWAKAAAFVTSPPLSPDP 311
Query: 306 STPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIWEKGVH 365
+TPDFL +LL+ DL TG+ +CTFNT QKA+GKD+FT IP G NG E+RMSVIW+K V
Sbjct: 312 TTPDFLNSLLSCGDLQVTGSAHCTFNTAQKAVGKDNFTLIPEGTNGTEERMSVIWDKAVV 371
Query: 366 SGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTHHQAVNF 425
+GKMDEN+FVAVTSTNAAK+FNLYPRKGRIAVGSDAD+VIWDP +TISAKTH+ ++ +
Sbjct: 372 TGKMDENQFVAVTSTNAAKVFNLYPRKGRIAVGSDADLVIWDPDSVKTISAKTHNSSLEY 431
Query: 426 NIFEGMVCHGVPLVTISRGKVVYEAGVFSVTAGDGKFIPRKPFAEYIYKRIKQRDRTCTP 485
NIFEGM C G PLV IS+GK+V E G VT G G++IPRKPF +++YKRIK R R
Sbjct: 432 NIFEGMECRGSPLVVISQGKIVLEDGTLHVTEGSGRYIPRKPFPDFVYKRIKARSRLAEL 491
Query: 486 TPVERAPYKGEVATLKSRVTKEDATAGTRKQAHP 519
V R Y G V + VT + T + + P
Sbjct: 492 RGVPRGLYDGPVCEVS--VTPKTVTPASSAKTDP 523
>1KCX-A nrPDB
Length = 518
Score = 646 bits (1667), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 301/492 (61%), Positives = 383/492 (77%), Gaps = 4/492 (0%)
Query: 6 RLLIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGID 65
RLLIRGGR++NDD S ADV +EDG+++ +G +L+ PGG ++ ++A G++V+PGGID
Sbjct: 9 RLLIRGGRIINDDQSFYADVYLEDGLIKQIGENLIVPGG----VKTIEANGRMVIPGGID 64
Query: 66 THTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWADPKV 125
+T++Q P G S DDF QGTKAAL+GGTTMIID +P+ G SL+ +FE W AD K
Sbjct: 65 VNTYLQKPSQGMTSADDFFQGTKAALAGGTTMIIDHVVPEPGSSLLTSFEKWHEAADTKS 124
Query: 126 CCDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEAFSRCKEI 185
CCDYSLHV +T W D V+EE+++LVQDKGVNSF+++MAYKDLY ++D +LYEAF+ K +
Sbjct: 125 CCDYSLHVDITSWYDGVREELEVLVQDKGVNSFQVYMAYKDLYQMSDSQLYEAFTFLKGL 184
Query: 186 GAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAVNCPLY 245
GA+ VHAENGDLIA+ K++L +GITGPEGH L RPE +EAEA RAI IA +NCP+Y
Sbjct: 185 GAVILVHAENGDLIAQEQKRILEMGITGPEGHALSRPEELEAEAVFRAIAIAGRINCPVY 244
Query: 246 IVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMGPPLRPDP 305
I VMSKSAA +IA AR+ G +V+GEPIAASLGTDGTHYW+K W AA V PPL PDP
Sbjct: 245 ITKVMSKSAADIIALARKKGPLVFGEPIAASLGTDGTHYWSKNWAKAAAFVTSPPLSPDP 304
Query: 306 STPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIWEKGVH 365
+TPD+L +LLA DL TG+ +C ++T QKA+GKD+FT IP GVNG+E+RM+V+W+K V
Sbjct: 305 TTPDYLTSLLACGDLQVTGSGHCPYSTAQKAVGKDNFTLIPEGVNGIEERMTVVWDKAVA 364
Query: 366 SGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTHHQAVNF 425
+GKMDEN+FVAVTSTNAAKIFNLYPRKGRIAVGSDAD+VIWDP +TI+AK+H V +
Sbjct: 365 TGKMDENQFVAVTSTNAAKIFNLYPRKGRIAVGSDADVVIWDPDKMKTITAKSHKSTVEY 424
Query: 426 NIFEGMVCHGVPLVTISRGKVVYEAGVFSVTAGDGKFIPRKPFAEYIYKRIKQRDRTCTP 485
NIFEGM CHG PLV IS+GK+V+E G SV+ G G+FIPRKPF E++Y+R++ R +
Sbjct: 425 NIFEGMECHGSPLVVISQGKIVFEDGNISVSKGMGRFIPRKPFPEHLYQRVRIRSKVFGL 484
Query: 486 TPVERAPYKGEV 497
V R Y G V
Sbjct: 485 HSVSRGMYDGPV 496
>4CNT-A nrPDB
Length = 570
Score = 645 bits (1665), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 300/497 (60%), Positives = 378/497 (76%), Gaps = 4/497 (0%)
Query: 6 RLLIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGID 65
RLLI+GGR+VNDD S AD+ +EDG+++ +G +L+ PGG ++ ++A GK+V+PGGID
Sbjct: 16 RLLIKGGRIVNDDQSFYADIYMEDGLIKQIGDNLIVPGG----VKTIEANGKMVIPGGID 71
Query: 66 THTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWADPKV 125
HTH Q P+ G ++DDF QGTKAAL+GGTTMIID +P+ SL EA+E WR WAD K
Sbjct: 72 VHTHYQMPYKGMTTVDDFFQGTKAALAGGTTMIIDHVVPEPESSLTEAYEKWREWADGKS 131
Query: 126 CCDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEAFSRCKEI 185
CCDY+LHV +T W+D VK+E++ L++DKGVNSF ++MAYKDLY V++ ELYE F+ E+
Sbjct: 132 CCDYALHVDITHWNDSVKQEVQNLIKDKGVNSFMVYMAYKDLYQVSNTELYEIFTCLGEL 191
Query: 186 GAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAVNCPLY 245
GAIAQVHAENGD+IA+ +ML +GITGPEGH L RPE +EAEA RAITIAS NCPLY
Sbjct: 192 GAIAQVHAENGDIIAQEQTRMLEMGITGPEGHVLSRPEELEAEAVFRAITIASQTNCPLY 251
Query: 246 IVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMGPPLRPDP 305
+ VMSKSAA +I+ AR+ G VV+GEPI ASLG DGTHYW+K W AA V PPL PDP
Sbjct: 252 VTKVMSKSAADLISQARKKGNVVFGEPITASLGIDGTHYWSKNWAKAAAFVTSPPLSPDP 311
Query: 306 STPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIWEKGVH 365
+TPD++ +LLA+ DL +G+ +CTF+T QKA+GKD+FT IP G NGVE+RMSVIW+K V
Sbjct: 312 TTPDYINSLLASGDLQLSGSAHCTFSTAQKAIGKDNFTAIPEGTNGVEERMSVIWDKAVA 371
Query: 366 SGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTHHQAVNF 425
+GKMDEN+FVAVTSTNAAKIFNLYPRKGRI+VGSD+D+VIWDP + +SAK H A +
Sbjct: 372 TGKMDENQFVAVTSTNAAKIFNLYPRKGRISVGSDSDLVIWDPDAVKIVSAKNHQSAAEY 431
Query: 426 NIFEGMVCHGVPLVTISRGKVVYEAGVFSVTAGDGKFIPRKPFAEYIYKRIKQRDRTCTP 485
NIFEGM G PLV I +GK++ E G VT G G+FIP PF++Y+YKRIK R +
Sbjct: 432 NIFEGMELRGAPLVVICQGKIMLEDGNLHVTQGAGRFIPCSPFSDYVYKRIKARRKMADL 491
Query: 486 TPVERAPYKGEVATLKS 502
V R Y G V L +
Sbjct: 492 HAVPRGMYDGPVFDLTT 508
>4CNS-A nrPDB
Length = 480
Score = 640 bits (1652), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 294/476 (61%), Positives = 371/476 (77%), Gaps = 4/476 (0%)
Query: 6 RLLIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGID 65
RLLI+GGR+VNDD S AD+ +EDG+++ +G +L+ PGG ++ ++A GK+V+PGGID
Sbjct: 6 RLLIKGGRIVNDDQSFYADIYMEDGLIKQIGDNLIVPGG----VKTIEANGKMVIPGGID 61
Query: 66 THTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWADPKV 125
HTH Q P+ G ++DDF QGTKAAL+GGTTMIID +P+ SL EA+E WR WAD K
Sbjct: 62 VHTHYQMPYKGMTTVDDFFQGTKAALAGGTTMIIDHVVPEPESSLTEAYEKWREWADGKS 121
Query: 126 CCDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEAFSRCKEI 185
CCDY+LHV +T W+D VK+E++ L++DKGVNSF ++MAYKDLY V++ ELYE F+ E+
Sbjct: 122 CCDYALHVDITHWNDSVKQEVQNLIKDKGVNSFMVYMAYKDLYQVSNTELYEIFTCLGEL 181
Query: 186 GAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAVNCPLY 245
GAIAQVHAENGD+IA+ +ML +GITGPEGH L RPE +EAEA RAITIAS NCPLY
Sbjct: 182 GAIAQVHAENGDIIAQEQTRMLEMGITGPEGHVLSRPEELEAEAVFRAITIASQTNCPLY 241
Query: 246 IVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMGPPLRPDP 305
+ VMSKSAA +I+ AR+ G VV+GEPI ASLG DGTHYW+K W AA V PPL PDP
Sbjct: 242 VTKVMSKSAADLISQARKKGNVVFGEPITASLGIDGTHYWSKNWAKAAAFVTSPPLSPDP 301
Query: 306 STPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIWEKGVH 365
+TPD++ +LLA+ DL +G+ +CTF+T QKA+GKD+FT IP G NGVE+RMSVIW+K V
Sbjct: 302 TTPDYINSLLASGDLQLSGSAHCTFSTAQKAIGKDNFTAIPEGTNGVEERMSVIWDKAVA 361
Query: 366 SGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTHHQAVNF 425
+GKMDEN+FVAVTSTNAAKIFNLYPRKGRI+VGSD+D+VIWDP + +SAK H A +
Sbjct: 362 TGKMDENQFVAVTSTNAAKIFNLYPRKGRISVGSDSDLVIWDPDAVKIVSAKNHQSAAEY 421
Query: 426 NIFEGMVCHGVPLVTISRGKVVYEAGVFSVTAGDGKFIPRKPFAEYIYKRIKQRDR 481
NIFEGM G PLV I +GK++ E G VT G G+FIP PF++Y+YKRIK R +
Sbjct: 422 NIFEGMELRGAPLVVICQGKIMLEDGNLHVTQGAGRFIPCSPFSDYVYKRIKARRK 477
>4B90-A nrPDB
Length = 586
Score = 615 bits (1587), Expect = e-176, Method: Compositional matrix adjust.
Identities = 297/509 (58%), Positives = 380/509 (74%), Gaps = 4/509 (0%)
Query: 2 AAPSRLLIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLP 61
+A R+LI+GG+VVNDD + ADV +E+G+++ +G +L+ PGGA +V+DA GKLV+P
Sbjct: 27 SASVRILIKGGKVVNDDCTHEADVYIENGIIQQVGRELMIPGGA----KVIDATGKLVIP 82
Query: 62 GGIDTHTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWA 121
GGIDT TH FM + +DDF+ GTKAAL GGTTMII +P K SL++A+E R A
Sbjct: 83 GGIDTSTHFHQTFMNATCVDDFYHGTKAALVGGTTMIIGHVLPDKETSLVDAYEKCRGLA 142
Query: 122 DPKVCCDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEAFSR 181
DPKVCCDY+LHV +TWW+ +VK EM+ LV++KGVNSF+MFM YKDLYM+ D ELY+
Sbjct: 143 DPKVCCDYALHVGITWWAPKVKAEMETLVREKGVNSFQMFMTYKDLYMLRDSELYQVLHA 202
Query: 182 CKEIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAVN 241
CK+IGAIA+VHAENG+L+AEGAK+ L LGITGPEG E+ RPE +EAEAT R ITIA+ +
Sbjct: 203 CKDIGAIARVHAENGELVAEGAKEALDLGITGPEGIEISRPEELEAEATHRVITIANRTH 262
Query: 242 CPLYIVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMGPPL 301
CP+Y+V+V S SA VIA A+ GKVV E A G HY++++W HAA +V PPL
Sbjct: 263 CPIYLVNVSSISAGDVIAAAKMQGKVVLAETTTAHATLTGLHYYHQDWSHAAAYVTVPPL 322
Query: 302 RPDPSTPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIWE 361
R D +T +LM+LLAND L +D+ F T QKA+GK+DFTKIP+GV+GV+DRMSVIWE
Sbjct: 323 RLDTNTSTYLMSLLANDTLNIVASDHRPFTTKQKAMGKEDFTKIPHGVSGVQDRMSVIWE 382
Query: 362 KGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTHHQ 421
+GV GKMDENRFVAVTS+NAAK+ NLYPRKGRI G+DAD+V+WDP+ T+TISA T Q
Sbjct: 383 RGVVGGKMDENRFVAVTSSNAAKLLNLYPRKGRIIPGADADVVVWDPEATKTISASTQVQ 442
Query: 422 AVNFNIFEGMVCHGVPLVTISRGKVVYEAGVFSVTAGDGKFIPRKPFAEYIYKRIKQRDR 481
+FN++E M CHGVPLVTISRG+VVYE GVF G GKF P + F + +YK++ QR++
Sbjct: 443 GGDFNLYENMRCHGVPLVTISRGRVVYENGVFMCAEGTGKFCPLRSFPDTVYKKLVQREK 502
Query: 482 TCTPTPVERAPYKGEVATLKSRVTKEDAT 510
T V+R PY G+VA + KE T
Sbjct: 503 TLKVRGVDRTPYLGDVAVVVHPGKKEMGT 531
>2FTW-A nrPDB
Length = 521
Score = 614 bits (1584), Expect = e-176, Method: Compositional matrix adjust.
Identities = 294/492 (59%), Positives = 366/492 (74%), Gaps = 7/492 (1%)
Query: 7 LLIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGIDT 66
+LI+ G VVNDD +DVLVE+G+++ + ++ P G++V+DA KL+LPGGIDT
Sbjct: 10 ILIKNGTVVNDDRYFKSDVLVENGIIKEISKNIEPK----EGIKVVDATDKLLLPGGIDT 65
Query: 67 HTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWADPKVC 126
HTH Q PFMG+ S+DDF GT+AA++GGTT IIDF IP +G SL+EA++ W+ WAD KV
Sbjct: 66 HTHFQLPFMGTVSVDDFDIGTQAAVAGGTTFIIDFVIPTRGQSLLEAYDQWKKWADEKVN 125
Query: 127 CDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEAFSRCKEIG 186
CDYSLHVA+TWWS+QV EM+ILV+++GVNSFK FMAYK+ +MVTD E+Y F RCKE+G
Sbjct: 126 CDYSLHVAITWWSEQVSREMEILVKERGVNSFKCFMAYKNSFMVTDQEMYHIFKRCKELG 185
Query: 187 AIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAVNCPLYI 246
AIAQVHAENGD++ EG KKML +GITGPEGHEL RPEA+EAEAT RAI IA +V P+YI
Sbjct: 186 AIAQVHAENGDMVFEGQKKMLEMGITGPEGHELSRPEALEAEATNRAIVIADSVCTPVYI 245
Query: 247 VHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMGPPLRPDPS 306
VHV S AA VI R++G VYGEPIAA LG DG+H WN +W HAA VMGPP+RPDP
Sbjct: 246 VHVQSIGAADVICKHRKEGVRVYGEPIAAGLGVDGSHMWNHDWRHAAAFVMGPPIRPDPR 305
Query: 307 TPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIWEKGVHS 366
T LM+ LA DL GTDNCTF QKA+GKDDFTKIPNGVNGVEDRMS++WE GV++
Sbjct: 306 TKGVLMDYLARGDLDCVGTDNCTFCADQKAMGKDDFTKIPNGVNGVEDRMSIVWENGVNT 365
Query: 367 GKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTHHQAVNFN 426
GK+ +FV TS+ A+IFN+YPRKGRI VG D DIVIWDP ++TIS THH AV+FN
Sbjct: 366 GKLTWCQFVRATSSERARIFNIYPRKGRIDVGCDGDIVIWDPNQSKTISKDTHHHAVDFN 425
Query: 427 IFEGMVCHGVPLVTISRGKVVYEAGVFSVTAGDGKFIPRKPFAEYIYKRIKQRD--RTCT 484
IFEG+ G+ + TI G +V+ S G G+F+PR PF ++ I+QRD R
Sbjct: 426 IFEGIKVTGIAVTTIVAGNIVWSDNKLSCVKGSGRFVPRPPFGP-VFDGIEQRDKVRNEL 484
Query: 485 PTPVERAPYKGE 496
V+R PY+ +
Sbjct: 485 LRKVDRKPYEDD 496
>5NKS-A nrPDB
Length = 573
Score = 613 bits (1581), Expect = e-176, Method: Compositional matrix adjust.
Identities = 292/492 (59%), Positives = 362/492 (73%), Gaps = 4/492 (0%)
Query: 6 RLLIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGID 65
RLLIRGGR+VNDD S ADV VEDG+++ +G +L+ PGG ++ +DA G +VLPGG+D
Sbjct: 17 RLLIRGGRIVNDDQSFYADVHVEDGLIKQIGENLIVPGG----IKTIDAHGLMVLPGGVD 72
Query: 66 THTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWADPKV 125
HT +Q P +G DDF QGTKAAL+GGTTMI+D P G SL+ A+E WR AD
Sbjct: 73 VHTRLQMPVLGMTPADDFCQGTKAALAGGTTMILDHVFPDTGVSLLAAYEQWRERADSAA 132
Query: 126 CCDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEAFSRCKEI 185
CCDYSLHV +T W + +KEE++ LV++KGVNSF +FMAYKD +D ++YE FS +++
Sbjct: 133 CCDYSLHVDITRWHESIKEELEALVKEKGVNSFLVFMAYKDRCQCSDSQMYEIFSIIRDL 192
Query: 186 GAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAVNCPLY 245
GA+AQVHAENGD++ E K++L LGITGPEGH L PE VEAEA RA+TIA NCPLY
Sbjct: 193 GALAQVHAENGDIVEEEQKRLLELGITGPEGHVLSHPEEVEAEAVYRAVTIAKQANCPLY 252
Query: 246 IVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMGPPLRPDP 305
+ VMSK AA IA A+R G VV+GEPI ASLGTDG+HYW+K W AA V PP+ PDP
Sbjct: 253 VTKVMSKGAADAIAQAKRRGVVVFGEPITASLGTDGSHYWSKNWAKAAAFVTSPPVNPDP 312
Query: 306 STPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIWEKGVH 365
+T D L LL++ DL TG+ +CTF T QKA+GKD+F IP G NG+E+RMS++WEK V
Sbjct: 313 TTADHLTCLLSSGDLQVTGSAHCTFTTAQKAVGKDNFALIPEGTNGIEERMSMVWEKCVA 372
Query: 366 SGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTHHQAVNF 425
SGKMDEN FVAVTSTNAAKIFN YPRKGR+AVGSDAD+VIW+PK T+ ISAKTH+ V +
Sbjct: 373 SGKMDENEFVAVTSTNAAKIFNFYPRKGRVAVGSDADLVIWNPKATKIISAKTHNLNVEY 432
Query: 426 NIFEGMVCHGVPLVTISRGKVVYEAGVFSVTAGDGKFIPRKPFAEYIYKRIKQRDRTCTP 485
NIFEG+ C G P V IS+G+V E G VT G G+F+PRK F +++YKRIK R+R
Sbjct: 433 NIFEGVECRGAPAVVISQGRVALEDGKMFVTPGAGRFVPRKTFPDFVYKRIKARNRLAEI 492
Query: 486 TPVERAPYKGEV 497
V R Y G V
Sbjct: 493 HGVPRGLYDGPV 504
>4B91-A nrPDB
Length = 484
Score = 604 bits (1557), Expect = e-173, Method: Compositional matrix adjust.
Identities = 287/481 (59%), Positives = 367/481 (76%), Gaps = 4/481 (0%)
Query: 2 AAPSRLLIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLP 61
+A R+LI+GG+VVNDD + ADV +E+G+++ +G +L+ PGGA +V+DA GKLV+P
Sbjct: 6 SASVRILIKGGKVVNDDCTHEADVYIENGIIQQVGRELMIPGGA----KVIDATGKLVIP 61
Query: 62 GGIDTHTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWA 121
GGIDT TH FM + +DDF+ GTKAAL GGTTMII +P K SL++A+E R A
Sbjct: 62 GGIDTSTHFHQTFMNATCVDDFYHGTKAALVGGTTMIIGHVLPDKETSLVDAYEKCRGLA 121
Query: 122 DPKVCCDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEAFSR 181
DPKVCCDY+LHV +TWW+ +VK EM+ LV++KGVNSF+MFM YKDLYM+ D ELY+
Sbjct: 122 DPKVCCDYALHVGITWWAPKVKAEMETLVREKGVNSFQMFMTYKDLYMLRDSELYQVLHA 181
Query: 182 CKEIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAVN 241
CK+IGAIA+VHAENG+L+AEGAK+ L LGITGPEG E+ RPE +EAEAT R ITIA+ +
Sbjct: 182 CKDIGAIARVHAENGELVAEGAKEALDLGITGPEGIEISRPEELEAEATHRVITIANRTH 241
Query: 242 CPLYIVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMGPPL 301
CP+Y+V+V S SA VIA A+ GKVV E A G HY++++W HAA +V PPL
Sbjct: 242 CPIYLVNVSSISAGDVIAAAKMQGKVVLAETTTAHATLTGLHYYHQDWSHAAAYVTVPPL 301
Query: 302 RPDPSTPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIWE 361
R D +T +LM+LLAND L +D+ F T QKA+GK+DFTKIP+GV+GV+DRMSVIWE
Sbjct: 302 RLDTNTSTYLMSLLANDTLNIVASDHRPFTTKQKAMGKEDFTKIPHGVSGVQDRMSVIWE 361
Query: 362 KGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTHHQ 421
+GV GKMDENRFVAVTS+NAAK+ NLYPRKGRI G+DAD+V+WDP+ T+TISA T Q
Sbjct: 362 RGVVGGKMDENRFVAVTSSNAAKLLNLYPRKGRIIPGADADVVVWDPEATKTISASTQVQ 421
Query: 422 AVNFNIFEGMVCHGVPLVTISRGKVVYEAGVFSVTAGDGKFIPRKPFAEYIYKRIKQRDR 481
+FN++E M CHGVPLVTISRG+VVYE GVF G GKF P + F + +YK++ QR++
Sbjct: 422 GGDFNLYENMRCHGVPLVTISRGRVVYENGVFMCAEGTGKFCPLRSFPDTVYKKLVQREK 481
Query: 482 T 482
T
Sbjct: 482 T 482
>6AJD-A nrPDB
Length = 485
Score = 491 bits (1264), Expect = e-139, Method: Compositional matrix adjust.
Identities = 248/484 (51%), Positives = 322/484 (66%), Gaps = 7/484 (1%)
Query: 7 LLIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGIDT 66
LLIRG VV + S ADVL +G+++A+G +L P+G VLD G+ ++PGGID
Sbjct: 3 LLIRGATVVTHEESYRADVLCANGLIQAIGENL----ETPSGCDVLDGGGQYLMPGGIDP 58
Query: 67 HTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWADPKVC 126
HTHMQ PFMG+ + +DF GT A L+GGTT IIDF IP SL+EAF TWR WA K
Sbjct: 59 HTHMQLPFMGTVASEDFFSGTAAGLAGGTTSIIDFVIPNPRQSLLEAFHTWRGWAQ-KSA 117
Query: 127 CDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEAFSRCKEIG 186
DY HVA+TWWSD+V EM LV GVNSFK FMAYK+ M D L +F RC E+G
Sbjct: 118 ADYGFHVAITWWSDEVAREMGELVAQHGVNSFKHFMAYKNAIMAADDTLVASFERCLELG 177
Query: 187 AIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAVNCPLYI 246
A+ VHAENG+L+ +K+LA G+TGPE H L RP VE EA RAI IA + PLY+
Sbjct: 178 AVPTVHAENGELVFHLQQKLLAQGLTGPEAHPLSRPPQVEGEAASRAIRIAETLGTPLYL 237
Query: 247 VHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMGPPLRPDPS 306
VH+ S+ A IA AR G+ VYGE +A L D + Y + +W AA +VM PP RP
Sbjct: 238 VHISSREALDEIAYARAKGQPVYGEVLAGHLLLDDSVYRHPDWATAAGYVMSPPFRPVEH 297
Query: 307 TPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIWEKGVHS 366
+ L L + +L TT TD+C F QKA+G+DDF+KIPNG G+EDRM+++W+ GV+S
Sbjct: 298 Q-EALWRGLQSGNLHTTATDHCCFCAEQKAMGRDDFSKIPNGTAGIEDRMALLWDAGVNS 356
Query: 367 GKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTHHQAVNFN 426
G++ + FVA+TSTN AKIFNL+PRKG I VG+DAD+V+WDP+G+RT+SA THHQ V+FN
Sbjct: 357 GRLSMHEFVALTSTNTAKIFNLFPRKGAIRVGADADLVLWDPQGSRTLSAATHHQRVDFN 416
Query: 427 IFEGMVCHGVPLVTISRGKVVYEAGVFSVTAGDGKFIPRKPFAEYIYKRIKQRDRTCTPT 486
IFEG G+P TIS+GK+++ AG G G+++ R P +Y+ + +R P
Sbjct: 417 IFEGRTVRGIPSHTISQGKLLWAAGDLRAEPGAGRYVER-PAYPSVYEVLGRRAERQRPV 475
Query: 487 PVER 490
VER
Sbjct: 476 AVER 479
>3DC8-A nrPDB
Length = 490
Score = 464 bits (1195), Expect = e-131, Method: Compositional matrix adjust.
Identities = 227/461 (49%), Positives = 299/461 (64%), Gaps = 9/461 (1%)
Query: 8 LIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGIDTH 67
+I+GG +V D + ADV VE G + +G +L +G LDA G V+PGGID H
Sbjct: 4 VIKGGTIVTADLTYKADVKVEGGRIVEIGPNL-------SGAETLDATGCYVMPGGIDPH 56
Query: 68 THMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWADPKVCC 127
TH++ PFMG+ S DDF GT+AAL+GGTTM++DFA+P G SL+EA W + + C
Sbjct: 57 THLEMPFMGTYSSDDFESGTRAALAGGTTMVVDFALPSPGQSLLEALTMWDN-KSTRANC 115
Query: 128 DYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEAFSRCKEIGA 187
DYS H+A+TWW +QV EM+ +V+DKG+N+FK FMAYK MV D E++ +F RC +GA
Sbjct: 116 DYSFHMAITWWGEQVFNEMETIVKDKGINTFKHFMAYKGALMVDDDEMFSSFQRCAALGA 175
Query: 188 IAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAVNCPLYIV 247
+ VHAENGD++A+ K+LA G +GPE H RP VE EA RAI IA CP+YIV
Sbjct: 176 LPLVHAENGDVVAQLQAKLLAEGNSGPEAHAYSRPAEVEGEAANRAIMIADMAGCPVYIV 235
Query: 248 HVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMGPPLRPDPST 307
H + A + I AR G V+GEP+ L D T Y++K+W HAA VM PP R +
Sbjct: 236 HTSCEQAHEAIRRARAKGMRVFGEPLIQHLTLDETEYFDKDWDHAARRVMSPPFR-NKLH 294
Query: 308 PDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIWEKGVHSG 367
D L LA+ L TD+C F T QK G DFT+IPNG G+EDRM ++W GV +G
Sbjct: 295 QDSLWAGLASGSLQVVATDHCAFTTEQKRFGVGDFTRIPNGTGGLEDRMPMLWTYGVATG 354
Query: 368 KMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTHHQAVNFNI 427
++ N FVAVTSTN AKI N+YP+KG I VG+DAD+V+WDPK ++TISAKT A+++N+
Sbjct: 355 RITMNEFVAVTSTNIAKILNIYPKKGAILVGADADLVVWDPKRSKTISAKTQQSAIDYNV 414
Query: 428 FEGMVCHGVPLVTISRGKVVYEAGVFSVTAGDGKFIPRKPF 468
FEG G+P T++RG V E G G G+F+ R PF
Sbjct: 415 FEGKTVTGLPRFTLTRGVVSIEEGTVKTQEGHGEFVRRDPF 455
>4TQT-A nrPDB
Length = 497
Score = 451 bits (1160), Expect = e-127, Method: Compositional matrix adjust.
Identities = 224/484 (46%), Positives = 312/484 (64%), Gaps = 11/484 (2%)
Query: 8 LIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGIDTH 67
+I+GG V+ D + AD+L+EDG + A+G L G V+DA+G V+PGGID H
Sbjct: 17 VIKGGTVITADRTFRADILIEDGKIAAIGDSL-------EGDEVIDASGCYVMPGGIDPH 69
Query: 68 THMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWADPKVCC 127
TH+Q PFMG+ S DDF GT AAL+GGTTM++DF +P G+L++A + W A K
Sbjct: 70 THLQMPFMGTYSSDDFDTGTAAALAGGTTMVVDFVLPDSEGNLLDALQEWFQKAG-KART 128
Query: 128 DYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEAFSRCKEIGA 187
DYS H+A+T W+++ EM +V+ +G+N+FK FMAYK MV D E++ +F RC E+GA
Sbjct: 129 DYSFHMAITGWNERTFNEMAEVVK-RGINTFKHFMAYKGALMVNDDEMFASFQRCAELGA 187
Query: 188 IAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAVNCPLYIV 247
+ VHAENGD++A+ K++A G GPE H RP VE EAT RAI IA PLY+V
Sbjct: 188 MPLVHAENGDIVAQLQAKLMAEGNDGPEAHAYSRPPEVEGEATNRAIMIADQAGVPLYVV 247
Query: 248 HVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMGPPLRPDPST 307
HV + + + I AR+ G V+GEP+ L D + Y N++W +AA VM PP R D
Sbjct: 248 HVSCEQSHEAIRRARQKGMRVFGEPLIQHLTLDESEYHNRDWDYAARRVMSPPFR-DKLN 306
Query: 308 PDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIWEKGVHSG 367
D L LA L TD+C F T QK G +FTKIPNG G+E+RM V+W +GV +G
Sbjct: 307 QDSLWAGLAAGSLQCVATDHCAFTTEQKRYGIGNFTKIPNGTGGLEERMPVLWTRGVRTG 366
Query: 368 KMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTHHQAVNFNI 427
++ N FVAVTSTN AKI N+YP+KG + G+DAD+VIWDP+ T+ ISAKT H ++++N+
Sbjct: 367 RLTPNEFVAVTSTNIAKILNIYPQKGAVVPGADADLVIWDPETTKKISAKTQHSSIDYNV 426
Query: 428 FEGMVCHGVPLVTISRGKVVYEAGVFSVTAGDGKFIPRKPFAEYIYKRIKQRDRTCTPTP 487
FEG G+P++T+SRG++ ++ G + GDG+FI R+P + + + Q P
Sbjct: 427 FEGFELKGLPIMTLSRGRIAFDKGQVTAKPGDGRFIEREPNGA-VNRALSQWKEIVAPRK 485
Query: 488 VERA 491
VER+
Sbjct: 486 VERS 489
>1YNY-A nrPDB
Length = 461
Score = 370 bits (949), Expect = e-103, Method: Compositional matrix adjust.
Identities = 204/463 (44%), Positives = 277/463 (59%), Gaps = 8/463 (1%)
Query: 9 IRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGIDTHT 68
IRGG VV + ADVL+E V A+GH L + G +DA G V+PGGID HT
Sbjct: 5 IRGGTVVTAADTYQADVLIEGERVVAIGHQL-----SVNGAEEIDATGCYVIPGGIDPHT 59
Query: 69 HMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWADPKVCCD 128
H+ PF G+ + DDF GT+AA GGTT I+DF + +KG SL A TW A K D
Sbjct: 60 HLDMPFGGTVTADDFFTGTRAAAFGGTTSIVDFCLTKKGESLKSAIATWHEKARGKAVID 119
Query: 129 YSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEAFSRCKEIGAI 188
Y H+ + +DQV EE++ ++ +G+ S K+FMAYK+++ D L++ + KE+GA+
Sbjct: 120 YGFHLMIAEANDQVLEELESVISSEGITSLKVFMAYKNVFQADDETLFKTLVKAKELGAL 179
Query: 189 AQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAVNCPLYIVH 248
QVHAENGD++ KK LA G T P H RP E EAT RAI + + LY+VH
Sbjct: 180 VQVHAENGDVLDYLTKKALAEGNTDPIYHAYTRPPEAEGEATGRAIALTALAGSQLYVVH 239
Query: 249 VMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMGPPLRPDPSTP 308
V SA + IA+AR G VYGE L D ++ A +V PPLR +
Sbjct: 240 VSCASAVQRIAEAREKGWNVYGETCPQYLALD-VSIMDQPDFEGAKYVWSPPLR-EKWNQ 297
Query: 309 DFLMNLLANDDLTTTGTDNCTFN-TCQKALGKDDFTKIPNGVNGVEDRMSVIWEKGVHSG 367
+ L + L N L T G+D+C FN QK LG+ DFTKIPNG +EDR+++++ +GV G
Sbjct: 298 EVLWSALKNGILQTVGSDHCPFNFRGQKELGRGDFTKIPNGGPLIEDRLTILYSEGVRQG 357
Query: 368 KMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTHHQAVNFNI 427
++ N+FV ++ST AAK+F ++PRKG IAVGSDADIVI+DP RT+S +THH V++N
Sbjct: 358 RISLNQFVDISSTKAAKLFGMFPRKGTIAVGSDADIVIFDPHVKRTLSVETHHMNVDYNP 417
Query: 428 FEGMVCHGVPLVTISRGKVVYEAGVFSVTAGDGKFIPRKPFAE 470
FEGM +G + +SRG V F AG G++I R F +
Sbjct: 418 FEGMEVYGEVVSVLSRGSFVVRDKQFVGQAGSGQYIKRTTFEQ 460
>3SFW-A nrPDB
Length = 461
Score = 368 bits (944), Expect = e-102, Method: Compositional matrix adjust.
Identities = 207/462 (44%), Positives = 276/462 (59%), Gaps = 8/462 (1%)
Query: 9 IRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGIDTHT 68
IR G VV + ADVL++ V A+G DL V+DA G +LPGGID HT
Sbjct: 5 IRNGTVVTASDTYQADVLIDGEKVVAIGSDL-----QATDAEVIDATGYYLLPGGIDPHT 59
Query: 69 HMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWADPKVCCD 128
H+ PF G+ + D+F GTKAA GGTT I+DF + KG SL A TW A K D
Sbjct: 60 HLDMPFGGTVTSDNFFTGTKAAAFGGTTSIVDFCLTSKGESLHSAIATWHEKARGKAVID 119
Query: 129 YSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEAFSRCKEIGAI 188
Y H+ V+ +D V EE++ +V ++G+ S K+FMAYK++ M D L++ R KE+GA+
Sbjct: 120 YGFHLMVSDANDHVLEELESVVNNEGITSLKVFMAYKNVLMADDETLFKTLIRAKELGAL 179
Query: 189 AQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAVNCPLYIVH 248
QVHAENGD++ K+ LA G T P H RP E EAT RAI + + + LY+VH
Sbjct: 180 VQVHAENGDVLDYLTKQALAEGNTDPIYHAYTRPPEAEGEATGRAIALTALADAQLYVVH 239
Query: 249 VMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMGPPLRPDPSTP 308
V A + IA+AR G VYGE L D T ++ A +V PPLR +
Sbjct: 240 VSCADAVRRIAEAREKGWNVYGETCPQYLVLDITALEKPDF-EGAKYVWSPPLR-EKWNQ 297
Query: 309 DFLMNLLANDDLTTTGTDNCTFN-TCQKALGKDDFTKIPNGVNGVEDRMSVIWEKGVHSG 367
D L + L N L T G+D+C FN + QK LG+ DFTKIPNG +EDRM++++ +GV G
Sbjct: 298 DVLWSALKNGILQTVGSDHCPFNFSGQKELGRRDFTKIPNGGPIIEDRMTILFSEGVRKG 357
Query: 368 KMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTHHQAVNFNI 427
K+ N+FV +TST AK+F ++P+KG IAVGSDADIV++DP RTIS +THH V++N
Sbjct: 358 KISLNQFVDITSTKVAKLFGMFPQKGTIAVGSDADIVLFDPTVQRTISVETHHMNVDYNP 417
Query: 428 FEGMVCHGVPLVTISRGKVVYEAGVFSVTAGDGKFIPRKPFA 469
FEGM HG + +SRG V F AG G+++ R FA
Sbjct: 418 FEGMQVHGDVISVLSRGAFVVRNKQFVGHAGAGRYVKRSTFA 459
>1K1D-A nrPDB
Length = 460
Score = 351 bits (900), Expect = 6e-97, Method: Compositional matrix adjust.
Identities = 195/463 (42%), Positives = 270/463 (58%), Gaps = 8/463 (1%)
Query: 8 LIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGIDTH 67
+I+ G +V + A +L++DG + +G +L G V+DA G V PGGID H
Sbjct: 4 IIKNGTIVTATDTYEAHLLIKDGKIAMIGQNL-----EEKGAEVIDAKGCYVFPGGIDPH 58
Query: 68 THMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWADPKVCC 127
TH+ P G+ + DDF GT AA GGTT IIDF + KG L +A ETW + A+ K
Sbjct: 59 THLDMPLGGTVTKDDFESGTIAAAFGGTTTIIDFCLTNKGEPLKKAIETWHNKANGKAVI 118
Query: 128 DYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEAFSRCKEIGA 187
DY H+ ++ +D V EE+ +++++G+ S K+FMAYK+++ D LY KE+GA
Sbjct: 119 DYGFHLMISEITDDVLEELPKVLEEEGITSLKVFMAYKNVFQADDGTLYCTLLAAKELGA 178
Query: 188 IAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAVNCPLYIV 247
+ VHAENGD+I KK LA G T P H L RP +E EAT RA + LY+V
Sbjct: 179 LVMVHAENGDVIDYLTKKALADGNTDPIYHALTRPPELEGEATGRACQLTELAGSQLYVV 238
Query: 248 HVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMGPPLRPDPST 307
HV A + IA+AR G V+GE L D + Y K A +V PPLR +
Sbjct: 239 HVTCAQAVEKIAEARNKGLDVWGETCPQYLVLDQS-YLEKPNFEGAKYVWSPPLR-EKWH 296
Query: 308 PDFLMNLLANDDLTTTGTDNCTFN-TCQKALGKDDFTKIPNGVNGVEDRMSVIWEKGVHS 366
+ L N L N L T G+D C+F+ QK LG+ DFTKIPNG +EDR+S+++ +GV
Sbjct: 297 QEVLWNALKNGQLQTLGSDQCSFDFKGQKELGRGDFTKIPNGGPIIEDRVSILFSEGVKK 356
Query: 367 GKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTHHQAVNFN 426
G++ N+FV + ST AK+F L+P+KG I VGSDAD+VI+DP R ISA+THH AV++N
Sbjct: 357 GRITLNQFVDIVSTRIAKLFGLFPKKGTIVVGSDADLVIFDPNIERVISAETHHMAVDYN 416
Query: 427 IFEGMVCHGVPLVTISRGKVVYEAGVFSVTAGDGKFIPRKPFA 469
FEGM G P+ + RG+ V F G G+++ R +
Sbjct: 417 AFEGMKVTGEPVSVLCRGEFVVRDKQFVGKPGYGQYLKRAKYG 459
>1GKQ-A nrPDB
Length = 458
Score = 344 bits (883), Expect = 5e-95, Method: Compositional matrix adjust.
Identities = 187/461 (40%), Positives = 265/461 (57%), Gaps = 7/461 (1%)
Query: 7 LLIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGIDT 66
LLI+ G ++ D AD+ E + +G +L AP G V+DA GK V PG ID
Sbjct: 2 LLIKNGEIITADSRYKADIYAEGETITRIGQNL----EAPPGTEVIDATGKYVFPGFIDP 57
Query: 67 HTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWADPKVC 126
H H+ PFM + + D G+KAAL GGTT I+ P + +E ++ W+S A+
Sbjct: 58 HVHIYLPFMATFAKDTHETGSKAALMGGTTTYIEMCCPSRNDDALEGYQLWKSKAEGNSY 117
Query: 127 CDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEAFSRCKEIG 186
CDY+ H+AV+ + ++ + +++ +V D G++SFK+F++YK+ + V D E+Y+ KE+G
Sbjct: 118 CDYTFHMAVSKFDEKTEGQLREIVAD-GISSFKIFLSYKNFFGVDDGEMYQTLRLAKELG 176
Query: 187 AIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAVNCPLYI 246
I H EN +L+ +K+L+ G TGPE HE RPEAVEAE T R T Y+
Sbjct: 177 VIVTAHCENAELVGRLQQKLLSEGKTGPEWHEPSRPEAVEAEGTARFATFLETTGATGYV 236
Query: 247 VHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMGPPLRPDPS 306
VH+ K A A+ G +Y E + D T Y + A ++M PPLR D
Sbjct: 237 VHLSCKPALDAAMAAKARGVPIYIESVIPHFLLDKT-YAERGGVEAMKYIMSPPLR-DKR 294
Query: 307 TPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIWEKGVHS 366
L + LA + T GTD+C F+T QK LGK+ FT IPNG+ +EDR+++++ GV
Sbjct: 295 NQKVLWDALAQGFIDTVGTDHCPFDTEQKLLGKEAFTAIPNGIPAIEDRVNLLYTYGVSR 354
Query: 367 GKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTHHQAVNFN 426
G++D +RFV ST AAK+F L+PRKG IAVGSDAD+V++DP+ TIS KT H ++N
Sbjct: 355 GRLDIHRFVDAASTKAAKLFGLFPRKGTIAVGSDADLVVYDPQYRGTISVKTQHVNNDYN 414
Query: 427 IFEGMVCHGVPLVTISRGKVVYEAGVFSVTAGDGKFIPRKP 467
FEG G P V RGKV G F G GK + R+P
Sbjct: 415 GFEGFEIDGRPSVVTVRGKVAVRDGQFVGEKGWGKLLRREP 455
>1NFG-A nrPDB
Length = 457
Score = 291 bits (745), Expect = 5e-79, Method: Compositional matrix adjust.
Identities = 175/472 (37%), Positives = 256/472 (54%), Gaps = 25/472 (5%)
Query: 7 LLIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGIDT 66
++I+ G +V D AD+ ++DG + +G L P R +DAAG+ V PGGID
Sbjct: 3 IIIKNGTIVTADGISRADLGIKDGKITQIGGALGP------AERTIDAAGRYVFPGGIDV 56
Query: 67 HTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWADPKVC 126
HTH++ ++S D F T AA GGTT I+DF +G SL EA W A K
Sbjct: 57 HTHVETVSFNTQSADTFATATVAAACGGTTTIVDFCQQDRGHSLAEAVAKWDGMAGGKSA 116
Query: 127 CDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEAFSRCKEIG 186
DY H+ V +D V EE+++L D G+ SFK+FMAY+ + M+ D+ L + + + G
Sbjct: 117 IDYGYHIIVLDPTDSVIEELEVL-PDLGITSFKVFMAYRGMNMIDDVTLLKTLDKAVKTG 175
Query: 187 AIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAVNCPLYI 246
++ VHAENGD K +A G T P H L RP VEAEAT RA+ +A VN P+YI
Sbjct: 176 SLVMVHAENGDAADYLRDKFVAEGKTAPIYHALSRPPRVEAEATARALALAEIVNAPIYI 235
Query: 247 VHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYW-------NKEWHHAAHHVMGP 299
VHV + + + + A+ G +L THY + A +V P
Sbjct: 236 VHVTCEESLEEVMRAKSRG--------VRALAETCTHYLYLTKEDLERPDFEGAKYVFTP 287
Query: 300 PLRPDPSTPDFLMNLLANDDLTTTGTDNCT-FNTCQKALGKDDFTKIPNGVNGVEDRMSV 358
P R D L N L N T +D+C+ K G++DF IPNG GVE+R+ +
Sbjct: 288 PARAKKDH-DVLWNALRNGVFETVSSDHCSWLFKGHKDRGRNDFRAIPNGAPGVEERLMM 346
Query: 359 IWEKGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKT 418
+++ GV+ G++ +FV + +T AK+F ++P+KG IAVGSDADIV+WDP+ I
Sbjct: 347 VYQ-GVNEGRISLTQFVELVATRPAKVFGMFPQKGTIAVGSDADIVLWDPEAEMVIEQTA 405
Query: 419 HHQAVNFNIFEGMVCHGVPLVTISRGKVVYEAGVFSVTAGDGKFIPRKPFAE 470
H A++++ +EG GVP + RGKV+ + G + DGKF+ R+ + +
Sbjct: 406 MHNAMDYSSYEGHKVKGVPKTVLLRGKVIVDEGSYVGEPTDGKFLKRRKYKQ 457
>2FTY-A nrPDB
Length = 559
Score = 211 bits (538), Expect = 4e-55, Method: Compositional matrix adjust.
Identities = 155/521 (29%), Positives = 252/521 (48%), Gaps = 68/521 (13%)
Query: 7 LLIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGIDT 66
L+I+ G + A++ V +G V+ + + P G+ V+DA G + PGGID
Sbjct: 5 LIIKNGIICTASDIYAAEIAVNNGKVQLIAASIDPSLGS----EVIDAEGAFITPGGIDA 60
Query: 67 HTHMQFPF-MGSRSIDDFHQGTKAALSGGTTMIIDFA---IPQKGGS-LIEAFET-WRSW 120
H H+ P + +D T++A++GGTT ++ F+ + +KG S L E+ + +
Sbjct: 61 HVHVDEPLKLLGDVVDTMEHATRSAVAGGTTTVVAFSTQDVSKKGPSALAESVKLDVDEY 120
Query: 121 ADPKVCCDYSLHV---AVTWWSDQVKEEMKILVQ----DKGVNSFKMFMAYKDLYMVTDL 173
++ + CDY LH+ + S + +E + + +Q D GV+S KMFM Y L ++D
Sbjct: 121 SEQTLYCDYGLHLILFQIEKPSVEARELLDVQLQAAYNDYGVSSVKMFMTYPGL-QISDY 179
Query: 174 ELYEAFSRCKEIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRA 233
++ A ++ G +HAENGD++ + + G+T H + RP VE EAT RA
Sbjct: 180 DIMSAMYATRKNGFTTMLHAENGDMVKWMIEALEEQGLTDAYYHGVSRPSIVEGEATNRA 239
Query: 234 ITIASAVNCPLYIVHVMSKSAAKVIADARRDGKVVYGE--PIAASLG---TDGTHYWNKE 288
IT+A+ ++ P+ VHV S AA+VI A+ G VY E P A L T H+ E
Sbjct: 240 ITLATTMDTPILFVHVSSPQAAEVIKQAQTKGLKVYAETCPQYALLSDAITRCHHHGEVE 299
Query: 289 WHH---------------------AAHHVMGPPLRPDPSTPDFLMNLLANDDLTTTGTDN 327
+ + ++ PP+RP+ T + + N T G+D+
Sbjct: 300 SYGVGIDLSSISESPFTNPDDRFIGSKYICSPPIRPE-GTQKSIWKGMNNGTFTIVGSDH 358
Query: 328 CTFNTCQKALGKD-------------DFTKIPNGVNGVEDRMSVIWEKGVHSGKMDEN-R 373
C++N +K +F IPNG+ GV RM ++++ G G + +
Sbjct: 359 CSYNYYEKTSTASKHRAFDPENNKNGEFRYIPNGLPGVCTRMPLLYDYGYLRGNLTSMMK 418
Query: 374 FVAVTSTNAAKIFNLYPRKGRIAVG-SDADIVIWDPKGTRT--------ISAKTHHQAVN 424
V + TN AK++ +YP+KG I G SDAD+VIW P ++ I+ K +
Sbjct: 419 LVEIQCTNPAKVYGMYPQKGSILPGVSDADLVIWYPDDSKKEYNSKPKLITNKLMEHNCD 478
Query: 425 FNIFEGMVCHGVPLVTISRGKVVYEAGVFSVTAGDGKFIPR 465
+ FEG+ P TI +GK+VY+ G DGK++ R
Sbjct: 479 YTPFEGIEIKNWPRYTIVKGKIVYKEGEILKENADGKYLKR 519
>1GKR-A nrPDB
Length = 458
Score = 171 bits (434), Expect = 6e-43, Method: Compositional matrix adjust.
Identities = 138/471 (29%), Positives = 223/471 (47%), Gaps = 29/471 (6%)
Query: 7 LLIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGIDT 66
++++ R+V+ D AD+LV+DG V A+ D + R +DA GK V+PG +D
Sbjct: 4 VIVKNCRLVSSDGITEADILVKDGKVAAISADTSDVEAS----RTIDAGGKFVMPGVVDE 59
Query: 67 HTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWADPKVC 126
H H+ + +R F +++A GG T II+ I + ++AF + A ++
Sbjct: 60 HVHIIDMDLKNR-YGRFELDSESAAVGGITTIIEMPITFPPTTTLDAFLEKKKQAGQRLK 118
Query: 127 CDYSLHVA-VTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYM---VTDLELYEAFSRC 182
D++L+ V ++++ + D G FK MA M V+D EL+E F
Sbjct: 119 VDFALYGGGVPGNLPEIRK-----MHDAGAVGFKSMMAASVPGMFDAVSDGELFEIFQEI 173
Query: 183 KEIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAVNC 242
G++ VHAEN +I K++ A G +E +P E EA RA+ + C
Sbjct: 174 AACGSVIVVHAENETIIQALQKQIKAAGGKDMAAYEASQPVFQENEAIQRALLLQKEAGC 233
Query: 243 PLYIVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMGPPLR 302
L ++HV + ++I A+ +G+ V+ E G Y N A +GP ++
Sbjct: 234 RLIVLHVSNPDGVELIHQAQSEGQDVHCE--------SGPQYLNITTDDAER--IGPYMK 283
Query: 303 PDPSTPDFLMNL-----LANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMS 357
P MN+ L N + T G+D+ K G D K NG G+E +
Sbjct: 284 VAPPVRSAEMNIRLWEQLENGLIDTLGSDHGGHPVEDKEPGWKDVWKAGNGALGLETSLP 343
Query: 358 VIWEKGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAK 417
++ GV+ G++ R V V AK+F +YP+KG + VGSDAD++I D + A
Sbjct: 344 MMLTNGVNKGRLSLERLVEVMCEKPAKLFGIYPQKGTLQVGSDADLLILDLDIDTKVDAS 403
Query: 418 THHQAVNFNIFEGMVCHGVPLVTISRGKVVYEAGVFSVTAGDGKFIPRKPF 468
++ F+GM G P++T+ RG VV E G V G G+F+ R+ +
Sbjct: 404 QFRSLHKYSPFDGMPVTGAPVLTMVRGTVVAEKGEVLVEQGFGQFVTRRNY 454
>3E74-A nrPDB
Length = 473
Score = 133 bits (334), Expect = 2e-31, Method: Compositional matrix adjust.
Identities = 126/466 (27%), Positives = 206/466 (44%), Gaps = 31/466 (6%)
Query: 7 LLIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGIDT 66
L+I+ G V+ ++ + V D+ V+ G + A+G DL G A V+DA+G +V PG +D
Sbjct: 25 LIIKNGTVILENEARVVDIAVKGGKIAAIGQDL---GDAK---EVMDASGLVVSPGMVDA 78
Query: 67 HTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEA-FETWRSWADPKV 125
HTH+ P G + + GT+AA GG T +I+ + Q ++ A E A K+
Sbjct: 79 HTHISEP--GRSHWEGYETGTRAAAKGGITTMIEMPLNQLPATVDRASIELKFDAAKGKL 136
Query: 126 CCDYS-LHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAY-------KDLYMVTDLELYE 177
D + L V++ D++ E + + GV FK F+A D V D + ++
Sbjct: 137 TIDAAQLGGLVSYNIDRLHE-----LDEVGVVGFKCFVATCGDRGIDNDFRDVNDWQFFK 191
Query: 178 AFSRCKEIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIA 237
+ E+G VH EN + E ++ G + RP E EA R + +A
Sbjct: 192 GAQKLGELGQPVLVHCENALICDELGEEAKREGRVTAHDYVASRPVFTEVEAIRRVLYLA 251
Query: 238 SAVNCPLYIVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVM 297
C L++ HV S + + AR++G+ + E D + +E A
Sbjct: 252 KVAGCRLHVCHVSSPEGVEEVTRARQEGQDITCESCPHYFVLDTDQF--EEIGTLAK--C 307
Query: 298 GPPLRPDPSTPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMS 357
PP+R D + L N ++ +D+ + C + + K G+ G++ M
Sbjct: 308 SPPIR-DLENQKGMWEKLFNGEIDCLVSDH---SPCPPEMKAGNIMKAWGGIAGLQSCMD 363
Query: 358 VIWEKGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAK 417
V++++ V M F + +TNAA IF L +KGRIA G DAD V P + ++
Sbjct: 364 VMFDEAVQKRGMSLPMFGKLMATNAADIFGLQ-QKGRIAPGKDADFVFIQPNSSYVLTND 422
Query: 418 THHQAVNFNIFEGMVCHGVPLVTISRGKVVYEAGVFSVTAGDGKFI 463
+ + G TI RG V+Y+ A G+FI
Sbjct: 423 DLEYRHKVSPYVGRTIGARITKTILRGDVIYDIEQGFPVAPKGQFI 468
>3HM7-A nrPDB
Length = 448
Score = 124 bits (311), Expect = 9e-29, Method: Compositional matrix adjust.
Identities = 124/455 (27%), Positives = 196/455 (43%), Gaps = 36/455 (7%)
Query: 7 LLIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGG-----APAGLRVLDAAGKLVLP 61
L+IR VV + + ADV + +G+V A+ PG PA +D G + P
Sbjct: 8 LIIRSSTVVTETTTYRADVAIRNGIVSAITE----PGSISSDDGPA----IDGTGLHLFP 59
Query: 62 GGIDTHTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLI-EAFETWRSW 120
G +D H H P G + F G+K+ +GG T D + ++ E + R
Sbjct: 60 GMVDVHVHFNEP--GRTEWEGFASGSKSLAAGGVTTYFDMPLNSNPPTITREELDKKRQL 117
Query: 121 ADPKVCCDYSLHVAVTWWSDQVKEEMKIL--VQDKGVNSFKMFMA---YKDLYMVTDLEL 175
A+ K DY +W V + L + D GV FK FM+ D D L
Sbjct: 118 ANEKSLVDYR------FWGGLVPGNIDHLQDLHDGGVIGFKAFMSECGTDDFQFSHDETL 171
Query: 176 YEAFSRCKEIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAIT 235
+ + +G+I VHAE+ +++ + + + RP E EA R +
Sbjct: 172 LKGMKKIAALGSILAVHAESNEMVNALTTIAIEEQRLTVKDYSEARPIVSELEAVERILR 231
Query: 236 IASAVNCPLYIVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHH 295
A CP++I HV S+ K I A+ +G V E L + E + A
Sbjct: 232 FAQLTCCPIHICHVSSRKVLKRIKQAKGEGVNVSVETCPHYLLFSLDEF--AEIGYLAK- 288
Query: 296 VMGPPLRPDPSTPDFLMNLLAND-DLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVED 354
PPLR D L+A + DL ++ + + + Q GK F ++ G+ G ++
Sbjct: 289 -CAPPLRERQEVEDLWDGLMAGEIDLISS---DHSPSLPQMKTGKTIF-EVWGGIAGCQN 343
Query: 355 RMSVIWEKGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTI 414
++V+ +G H KM + V + ST AK F LYP+KG I VG++A + D + T+
Sbjct: 344 TLAVMLTEGYHKRKMPLTQIVQLLSTEPAKRFGLYPQKGTIQVGAEASFTLIDLNESYTL 403
Query: 415 SAKTHHQAVNFNIFEGMVCHGVPLVTISRGKVVYE 449
+A + + + G G TI +GK VY+
Sbjct: 404 NASDLYYRHPISPYVGQRFRGKVKHTICQGKHVYQ 438
>3GRI-A nrPDB
Length = 424
Score = 105 bits (261), Expect = 6e-23, Method: Compositional matrix adjust.
Identities = 113/449 (25%), Positives = 182/449 (40%), Gaps = 37/449 (8%)
Query: 8 LIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGIDTH 67
LI+ G+V+ + + AD+L++ V++ + + P G + ++DA G V PG +D H
Sbjct: 3 LIKNGKVLQNGELQQADILIDGKVIKQIAPAIEPSNG----VDIIDAKGHFVSPGFVDVH 58
Query: 68 THMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWADPKVCC 127
H++ P G + GTKAA GG T + + +E FE + D
Sbjct: 59 VHLREP--GGEYKETIETGTKAAARGGFTTVCPMPNTRPVPDSVEHFEALQKLID----- 111
Query: 128 DYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKD-LYMVTDLELYEAFSRCKEIG 186
D + + + S ++ K LV + F D + + T +YE ++
Sbjct: 112 DNAQVRVLPYASITTRQLGKELVDFPALVKEGAFAFTDDGVGVQTASMMYEGMIEAAKVN 171
Query: 187 AIAQVHAENGDLIAEGA----KKMLALGITGPEGHELCRPEAVEAEATLRAITIASAVNC 242
H E+ LI GA K+ LGI G P E+ R + +A A C
Sbjct: 172 KAIVAHCEDNSLIYGGAMHEGKRSKELGIPG-------IPNICESVQIARDVLLAEAAGC 224
Query: 243 PLYIVHVMSKSAAKVIADARRDGKVVYGE--PIAASLGTDGTHYWNKEWHHAAHHVMGPP 300
++ HV +K + +VI DA+R G V E P L D N A + M PP
Sbjct: 225 HYHVCHVSTKESVRVIRDAKRAGIHVTAEVTPHHLLLTEDDIPGNN------AIYKMNPP 278
Query: 301 LRPDPSTPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIW 360
LR L LL + + TD+ +KA K P G+ G E +++
Sbjct: 279 LRSTEDREALLEGLL-DGTIDCIATDHAPHARDEKA---QPMEKAPFGIVGSETAFPLLY 334
Query: 361 EKGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTHH 420
V +G + V + + FNL G + AD+ I D + I +
Sbjct: 335 THFVKNGDWTLQQLVDYLTIKPCETFNL--EYGTLKENGYADLTIIDLDSEQEIKGEDFL 392
Query: 421 QAVNFNIFEGMVCHGVPLVTISRGKVVYE 449
+ F G +G P++T+ G+V +E
Sbjct: 393 SKADNTPFIGYKVYGNPILTMVEGEVKFE 421
>3MPG-A nrPDB
Length = 428
Score = 101 bits (252), Expect = 7e-22, Method: Compositional matrix adjust.
Identities = 114/452 (25%), Positives = 177/452 (39%), Gaps = 43/452 (9%)
Query: 8 LIRGGRVVNDDFSEVA-DVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGIDT 66
L + GR +N++ VA D+LV+DG + + ++ V+D GKL+ PG +D
Sbjct: 4 LFKNGRYMNEEGKIVATDLLVQDGKIAKVAENITADNA-----EVIDVNGKLIAPGLVDV 58
Query: 67 HTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWADPKVC 126
H H++ P G + GT AA GG T I + E E ++ K
Sbjct: 59 HVHLREP--GGEHKETIETGTLAAAKGGFTTICAMPNTRPVPDCREHMEDLQNRIKEKAH 116
Query: 127 CDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMF---MAYKDLYMVTDLELYEAFSRCK 183
+ + A+T Q EM K + +F + +D M + A R
Sbjct: 117 VNVLPYGAITVR--QAGSEMTDFETLKELGAFAFTDDGVGVQDASM-----MLAAMKRAA 169
Query: 184 EIGAIAQVHAENGDLIAEGA----KKMLALGITGPEGHELCRPEAVEAEATLRAITIASA 239
++ H E LI +G K G+ G P E+ R I +A A
Sbjct: 170 KLNMAVVAHCEENTLINKGCVHEGKFSEKHGLNGI-------PSVCESVHIARDILLAEA 222
Query: 240 VNCPLYIVHVMSKSAAKVIADARRDGKVVYGE--PIAASLGTDGTHYWNKEWHHAAHHVM 297
+C ++ HV +K + +VI DA+R G V E P L D + + M
Sbjct: 223 ADCHYHVCHVSTKGSVRVIRDAKRAGIKVTAEVTPHHLVLCEDDIPSADPNFK------M 276
Query: 298 GPPLRPDPSTPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMS 357
PPLR + LL + + TD+ +KA G + P G+ G E
Sbjct: 277 NPPLRGKEDHEALIEGLL-DGTIDMIATDHAPHTAEEKAQG---IERAPFGITGFETAFP 332
Query: 358 VIWEKGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAK 417
+++ V G + + + + A F L GR+ G ADI I D + I
Sbjct: 333 LLYTNLVKKGIITLEQLIQFLTEKPADTFGL--EAGRLKEGRTADITIIDLEQEEEIDPT 390
Query: 418 THHQAVNFNIFEGMVCHGVPLVTISRGKVVYE 449
T F G C G P++TI GK+ ++
Sbjct: 391 TFLSKGKNTPFAGWKCQGWPVMTIVGGKIAWQ 422
>2Z00-A nrPDB
Length = 426
Score = 73.2 bits (178), Expect = 3e-13, Method: Compositional matrix adjust.
Identities = 107/466 (22%), Positives = 179/466 (38%), Gaps = 65/466 (13%)
Query: 7 LLIRGGRVVNDDFSE-VADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGID 65
+LIR R+V+ ADVL+ +G + +L GG +V+D G + PG +D
Sbjct: 2 ILIRNVRLVDARGERGPADVLIGEGRILSLE------GGE--AKQVVDGTGCFLAPGFLD 53
Query: 66 THTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWADPKV 125
H H++ P G +D G AA+ GG T ++ + EA + A K
Sbjct: 54 LHAHLREP--GEEVKEDLFSGLLAAVRGGYTDLVSMPNTKPPVDTPEAVRALKEKA--KA 109
Query: 126 CCDYSLHVAVTWWSDQ----------VKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLEL 175
LH A Q ++E +L+ D G + + L M L
Sbjct: 110 LGLARLHPAAALTEKQEGKTLTPAGLLREAGAVLLTDDGRTNEDAGVLAAGLLMAAPL-- 167
Query: 176 YEAFSRCKEIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRP-EAVEAEA----- 229
G VHAE+ L G GP L P EAEA
Sbjct: 168 ----------GLPVAVHAEDAGLRRNGVMN------DGPLADLLGLPGNPPEAEAARIAR 211
Query: 230 ---TLRAITIASAVNCPLYIVHVMSKSAAKVIADARRDGKVVYGE--PIAASLGTDGTHY 284
LR S L++ H+ +K +++ +A+R G V E P +L +
Sbjct: 212 DLEVLRYALRRSPATPRLHVQHLSTKRGLELVREAKRAGLPVTAEATPHHLTLTEEALRT 271
Query: 285 WNKEWHHAAHHVMGPPLRPDPSTPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTK 344
++ + + PPLR + L LL + L TD+ +K + D +
Sbjct: 272 FDPLFK------VAPPLRGEEDREALLEGLL-DGTLDAIATDHAPHTLAEK---EKDLLR 321
Query: 345 IPNGVNGVEDRMSVIWEKGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIV 404
P G+ +E +++ + R V + + ++ L P + G++A +V
Sbjct: 322 APFGIPSLEVAFPLLYTELHLKRGFPLQRLVELFTDGPRRVLGLPPL--HLEEGAEASLV 379
Query: 405 IWDPKGTRTISAKTHHQAVNFNIFEGMVCHGVPLVTISRGKVVYEA 450
+ PK R + ++ + G V G P++T+ G++V+EA
Sbjct: 380 LLSPK-ERPVDPSAFASKARYSPWAGWVLGGWPVLTLVAGRIVHEA 424
>1XRT-A nrPDB
Length = 467
Score = 66.6 bits (161), Expect = 3e-11, Method: Compositional matrix adjust.
Identities = 104/465 (22%), Positives = 190/465 (40%), Gaps = 67/465 (14%)
Query: 6 RLLIRGGRVVN--DDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGG 63
+L+++ G V++ + D+LVE+G ++ + ++L P ++DA G +V PG
Sbjct: 48 KLIVKNGYVIDPSQNLEGEFDILVENGKIKKIDKNILVPEA-----EIIDAKGLIVCPGF 102
Query: 64 IDTHTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWADP 123
ID H H++ P G +D G++ A++GG T I+ +P + D
Sbjct: 103 IDIHVHLRDP--GQTYKEDIESGSRCAVAGGFTTIV--CMPNTNPPI-----------DN 147
Query: 124 KVCCDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLE--------- 174
+Y L + + +V I KG F + K+ V +
Sbjct: 148 TTVVNYILQKSKSVGLCRVLPTGTITKGRKG-KEIADFYSLKEAGCVAFTDDGSPVMDSS 206
Query: 175 -LYEAFSRCKEIGAIAQVHAENGDL----IAEG-AKKMLALGITGPEGHELCRPEAVEAE 228
+ +A ++G H E+ L I EG +L L PE E+
Sbjct: 207 VMRKALELASQLGVPIMDHCEDDKLAYGVINEGEVSALLGLSSRAPEAEEI--------- 257
Query: 229 ATLRAITIASAVNCPLYIVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKE 288
R +A ++I HV +K + ++I + G I + + + +E
Sbjct: 258 QIARDGILAQRTGGHVHIQHVSTKLSLEIIEFFKEKGV-----KITCEVNPNHLLFTERE 312
Query: 289 -WHHAAHHVMGPPLRPDPSTPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPN 347
+ A+ + PPLR L+ + + TD+ T +K L +F +P
Sbjct: 313 VLNSGANARVNPPLRKKEDRLA-LIEGVKRGIIDCFATDHAPHQTFEKEL--VEFA-MP- 367
Query: 348 GVNGVEDRMSV---IWEKGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIV 404
G+ G++ + ++ KG+ S K + + + + N A+I + G + +GS ADI
Sbjct: 368 GIIGLQTALPSALELYRKGIISLK----KLIEMFTINPARIIGV--DLGTLKLGSPADIT 421
Query: 405 IWDPKGTRTISAKTHHQAVNFNIFEGMVCHGVPLVTISRGKVVYE 449
I+DP ++ +T+ G V G + TI GK+VY+
Sbjct: 422 IFDPNKEWILNEETNLSKSRNTPLWGKVLKGKVIYTIKDGKMVYK 466
>2GWN-A nrPDB
Length = 452
Score = 53.5 bits (127), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 87/453 (19%), Positives = 172/453 (37%), Gaps = 28/453 (6%)
Query: 6 RLLIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGID 65
++L+R + N+ + V+++ + + LP + V++ +G + PG ID
Sbjct: 5 KILLRNALITNEGKTFPGSVMIDGAFISRIIEGELPADDNLSADEVIECSGLRLFPGCID 64
Query: 66 THTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWADPKV 125
H + P + ++ ++AA++GG T +D ++ E R
Sbjct: 65 DQVHFREPGLTHKAT--IASESRAAVAGGVTSFMDMPNTNPPTTMWERLLEKRQIGADTA 122
Query: 126 CCDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLE--LYEAFSRCK 183
+Y T +D + E + V V K+F+ M+ D + L + F C
Sbjct: 123 WANYGFFFGGT--NDNIDEIKR--VDKHLVPGLKLFLGSSTGNMLVDNKETLEKIFGECD 178
Query: 184 EIGAIAQVHAENGDLIAEGAKKMLA-----LGITGPEGHELCRPEAVEAEATLRAITIAS 238
+ A H E ++I + A L I H L R E ++ A+ +A
Sbjct: 179 LLIA---THCEKEEIIRANKEHYKAKYGNDLDI---HFHPLIRSEEACYRSSAEAVELAE 232
Query: 239 AVNCPLYIVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMG 298
+N L+I+H+ ++ + R+ + I + + + + ++ + +
Sbjct: 233 RMNARLHILHLSTEKELSLF----RNDIPTAQKRITSEVCVHHLWFSDTDYGRLGNRIKW 288
Query: 299 PPLRPDPSTPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSV 358
P S + L + N + TD+ +K + + +G V+ +
Sbjct: 289 NPAIKKESDREALRAAVRNGRIDIIATDHAPHLLREK---EGSCLQAASGGPLVQHSLLA 345
Query: 359 IWEKGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKT 418
+ E + G V+ T+ A +F + ++G I G AD+V+ DP T+SA
Sbjct: 346 LLEL-CNQGIFSIEEIVSKTAHIPATLFAI-EKRGYIRPGYYADLVLVDPSSPHTVSADN 403
Query: 419 HHQAVNFNIFEGMVCHGVPLVTISRGKVVYEAG 451
++ FEG T G + Y G
Sbjct: 404 ILSLCGWSPFEGFTFSHSVAYTFVNGCLAYAKG 436
>6HG1-A nrPDB
Length = 371
Score = 44.7 bits (104), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 31/84 (36%), Positives = 45/84 (53%), Gaps = 7/84 (8%)
Query: 56 GKLV-LPGGIDTHTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIE-- 112
KLV LPG ID H H++ P G +DF GT AAL+GG TM+ A+P +I+
Sbjct: 1 AKLVRLPGLIDVHVHLREP--GGTHKEDFASGTAAALAGGITMVC--AMPNTRPPIIDAP 56
Query: 113 AFETWRSWADPKVCCDYSLHVAVT 136
A + A+ CD++L + +
Sbjct: 57 ALALAQKLAEAGARCDFALFLGAS 80
Score = 31.6 bits (70), Expect = 0.85, Method: Compositional matrix adjust.
Identities = 28/125 (22%), Positives = 53/125 (42%), Gaps = 9/125 (7%)
Query: 343 TKIPNGVNGVEDRMSVIWEKGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDAD 402
++ P G G+E + ++ V G++ + + N +IF+L P++ D
Sbjct: 242 SRPPPGFPGLETMLPLLL-TAVSEGRLSLDDLLQRLHHNPRRIFHLPPQE-------DTY 293
Query: 403 IVIWDPKGTRTISAKTHHQAVNFNIFEGMVCHGVPLVTISRGKVVYEAGVFSVTAGDGKF 462
+ + D + TI + ++ FEG G + RG+V Y G V G G+
Sbjct: 294 VEV-DLEHEWTIPSHMPFSKAHWTPFEGQKVKGTVRRVVLRGEVAYIDGQVLVPPGYGQD 352
Query: 463 IPRKP 467
+ + P
Sbjct: 353 VRKWP 357
>2VUN-A nrPDB
Length = 386
Score = 40.8 bits (94), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 33/107 (30%), Positives = 54/107 (50%), Gaps = 11/107 (10%)
Query: 5 SRLLIRG-GRVVNDDFS----EVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLV 59
S+ +I+ G++V+ D + ++VEDG++ A+G + L A ++DAAG V
Sbjct: 2 SKTIIKNIGKIVSGDIKSPVLQADTIVVEDGLIAAIGGEELMKDAGDA--TIIDAAGSTV 59
Query: 60 LPGGIDTHTHMQ-FPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQ 105
PG +DTH H+ + + DF +AL GG T +I P
Sbjct: 60 TPGLLDTHVHVSGGDYAPRQKTMDF---ISSALHGGVTTMISAGSPH 103
>1FWC-C nrPDB
Length = 567
Score = 40.0 bits (92), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 31/82 (37%), Positives = 41/82 (50%), Gaps = 16/82 (19%)
Query: 23 ADVLVEDGVVRALGH----DLLPPGGAPAG--LRVLDAAGKLVLPGGIDTHTHMQFPFMG 76
AD+ V+DG + A+G D+ P P G V+ A GK+V GGIDTH H P
Sbjct: 84 ADIGVKDGRIFAIGKAGNPDIQPNVTIPIGAATEVIAAEGKIVTAGGIDTHIHWICP--- 140
Query: 77 SRSIDDFHQGTKAALSGGTTMI 98
Q +A +SG TTM+
Sbjct: 141 -------QQAEEALVSGVTTMV 155
Score = 28.9 bits (63), Expect = 5.5, Method: Compositional matrix adjust.
Identities = 13/36 (36%), Positives = 19/36 (52%)
Query: 373 RFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDP 408
R++A + N A + G I VG AD+V+W P
Sbjct: 402 RYIAKYTINPALTHGIAHEVGSIEVGKLADLVVWSP 437
>4V1Y-A nrPDB
Length = 494
Score = 39.3 bits (90), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 28/61 (45%), Positives = 38/61 (62%), Gaps = 11/61 (18%)
Query: 13 RVVNDDFSEVADVLVEDGVVRALG--HDLLPPGGAPAGLRVLDAAGKLVLPGGIDTHTHM 70
RV+ D + V V+DG + ALG + +PP PA RV+DA GK+VLPG I+ HTH+
Sbjct: 39 RVLGDSW-----VHVQDGRIVALGVHAESVPP---PAD-RVIDARGKVVLPGFINAHTHV 89
Query: 71 Q 71
Sbjct: 90 N 90
>2VHL-A nrPDB
Length = 396
Score = 37.4 bits (85), Expect = 0.014, Method: Compositional matrix adjust.
Identities = 16/29 (55%), Positives = 21/29 (72%)
Query: 377 VTSTNAAKIFNLYPRKGRIAVGSDADIVI 405
+TS NAAK ++ RKG + VG DAD+VI
Sbjct: 342 ITSENAAKQLGIFDRKGSVTVGKDADLVI 370
>5T5I-A nrPDB
Length = 569
Score = 36.6 bits (83), Expect = 0.028, Method: Compositional matrix adjust.
Identities = 22/68 (32%), Positives = 36/68 (52%), Gaps = 12/68 (17%)
Query: 6 RLLIRGGRV---VNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPG 62
+I+ G V +N E D+ V+DG + D +V+DA+GK+V+PG
Sbjct: 2 EYIIKNGFVYCPLNGVDGEKMDICVKDGKIVESVSD---------SAKVIDASGKIVMPG 52
Query: 63 GIDTHTHM 70
G+D H+H+
Sbjct: 53 GVDPHSHI 60
Score = 32.0 bits (71), Expect = 0.65, Method: Compositional matrix adjust.
Identities = 13/31 (41%), Positives = 20/31 (64%)
Query: 377 VTSTNAAKIFNLYPRKGRIAVGSDADIVIWD 407
+T +AK+ L KG + VG+DADI ++D
Sbjct: 441 ITRATSAKVLGLSDTKGHLGVGADADIAVYD 471
>1RK6-A nrPDB
Length = 496
Score = 35.4 bits (80), Expect = 0.053, Method: Compositional matrix adjust.
Identities = 27/70 (38%), Positives = 39/70 (55%), Gaps = 7/70 (10%)
Query: 2 AAPSRLLIRGGRVVNDDFS--EVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLV 59
A P ++ GG V++ + +ADV V + A+G DL A + R +D AGK+V
Sbjct: 18 ATPFDYILSGGTVIDGTNAPGRLADVGVRGDRIAAVG-DL----SASSARRRIDVAGKVV 72
Query: 60 LPGGIDTHTH 69
PG ID+HTH
Sbjct: 73 SPGFIDSHTH 82
>3MKV-A nrPDB
Length = 426
Score = 35.0 bits (79), Expect = 0.087, Method: Compositional matrix adjust.
Identities = 20/67 (29%), Positives = 35/67 (52%), Gaps = 7/67 (10%)
Query: 7 LLIRGGRVVNDDFSEVA---DVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGG 63
L R G +++ D ++ ++L+EDG +R + + A V+D GK ++PG
Sbjct: 6 FLFRNGALLDPDHPDLLQGFEILIEDGFIREVSDKPIKSSNA----HVIDVKGKTIMPGL 61
Query: 64 IDTHTHM 70
ID H H+
Sbjct: 62 IDLHVHV 68
>3OOQ-A nrPDB
Length = 396
Score = 34.7 bits (78), Expect = 0.098, Method: Compositional matrix adjust.
Identities = 16/47 (34%), Positives = 26/47 (55%), Gaps = 5/47 (10%)
Query: 24 DVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGIDTHTHM 70
DVLV +G V +G ++ P ++D GK + PG +D H+H+
Sbjct: 25 DVLVSNGKVEKVGENIEDPDA-----EIVDLTGKFLFPGFVDAHSHI 66
Score = 34.3 bits (77), Expect = 0.12, Method: Compositional matrix adjust.
Identities = 15/36 (41%), Positives = 20/36 (55%)
Query: 371 ENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIW 406
E + + + N AKI L R G I G DAD+V+W
Sbjct: 329 EEDLLKILTVNPAKILGLEDRIGSIEPGKDADLVVW 364
>2BB0-A nrPDB
Length = 421
Score = 34.3 bits (77), Expect = 0.13, Method: Compositional matrix adjust.
Identities = 23/58 (39%), Positives = 33/58 (56%), Gaps = 7/58 (12%)
Query: 26 LVEDGVVRALGHDLLPPG--GAPAGLR---VLDAAGKLVLPGGIDTHTHMQFPFMGSR 78
++ED VV ++ G GA AG ++D +G+LV PG +D HTH+ F GSR
Sbjct: 34 VIEDAVVGIHEQKIVFAGQKGAEAGYEADEIIDCSGRLVTPGLVDPHTHLVFG--GSR 89
>2OOF-A nrPDB
Length = 416
Score = 33.9 bits (76), Expect = 0.17, Method: Compositional matrix adjust.
Identities = 25/74 (33%), Positives = 38/74 (51%), Gaps = 13/74 (17%)
Query: 53 DAAGKLVLPGGIDTHTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFA-IPQKGGSLI 111
D GKLV PG ID HTH+ F GSR+ ++F K + +A I +KGG +I
Sbjct: 58 DMKGKLVTPGLIDCHTHLIFA--GSRA-EEFELRQKG---------VPYAEIARKGGGII 105
Query: 112 EAFETWRSWADPKV 125
R+ ++ ++
Sbjct: 106 STVRATRAASEDQL 119
>3K7I-B nrPDB
Length = 187
Score = 33.9 bits (76), Expect = 0.18, Method: Compositional matrix adjust.
Identities = 32/118 (27%), Positives = 52/118 (44%), Gaps = 3/118 (2%)
Query: 307 TPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIW-EKGVH 365
TP++ +++ D+ TG D C+ L + + N GV+ R++ W E G H
Sbjct: 67 TPNYNPDIIFKDE-ENTGADRLMTQRCKDRLNSLAIS-VMNQWPGVKLRVTKGWDEDGHH 124
Query: 366 SGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTHHQAV 423
S + AV T + + N Y R+AV + D V ++ K S K+ H A
Sbjct: 125 SEESLHYEGRAVDITTSDRDRNKYGLLARLAVEAGFDWVYYESKAHVHCSVKSEHSAA 182
>6ASO-A nrPDB
Length = 424
Score = 33.5 bits (75), Expect = 0.22, Method: Compositional matrix adjust.
Identities = 28/102 (27%), Positives = 44/102 (43%), Gaps = 13/102 (12%)
Query: 228 EATLRAITIASAVNCPLYIVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNK 287
E +R I + S N + I+ SK AAK++ +G G+ I + D Y+N
Sbjct: 314 EKDIRKILLVSDFNGAI-IIFRDSKFAAKMLMIL--NGSQFQGKVIRSGTINDMKRYYNN 370
Query: 288 EWHHAAHHV---------MGPPLRPDPSTPDFLMNLLANDDL 320
+ +H+ HV GP L+ PD ++NDD
Sbjct: 371 QQNHSMKHVKPSCINMMEKGPNLQVKKKIPD-KQEQMSNDDF 411
>6NBO-A nrPDB
Length = 402
Score = 33.1 bits (74), Expect = 0.33, Method: Compositional matrix adjust.
Identities = 23/64 (35%), Positives = 32/64 (50%), Gaps = 7/64 (10%)
Query: 7 LLIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGIDT 66
LLIR R DD D+L+E + G P AP G + + AG + LPG ++
Sbjct: 12 LLIRNVRTGADD---ALDILIEGDRIARTG----PSLDAPPGCAIEEGAGAIALPGLVEG 64
Query: 67 HTHM 70
HTH+
Sbjct: 65 HTHL 68
>2PUZ-A nrPDB
Length = 419
Score = 33.1 bits (74), Expect = 0.34, Method: Compositional matrix adjust.
Identities = 17/63 (26%), Positives = 27/63 (42%)
Query: 368 KMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTHHQAVNFNI 427
+M + T+ NAAK L G + G AD IWD + + + ++ I
Sbjct: 352 RMTVEECLTATTRNAAKALGLLAETGTLEAGKSADFAIWDIERPAELVYRIGFNPLHARI 411
Query: 428 FEG 430
F+G
Sbjct: 412 FKG 414
>2Z1T-A nrPDB
Length = 343
Score = 32.7 bits (73), Expect = 0.34, Method: Compositional matrix adjust.
Identities = 20/52 (38%), Positives = 28/52 (53%), Gaps = 1/52 (1%)
Query: 414 ISAKTHHQAVNFNIFEGMVCHGVPLVTISRGKVVYEAGVFSVTAGDGKFIPR 465
+ A+ + + F + EG+ + V S GK EAGVF VT GD K +PR
Sbjct: 85 LGARPRYLSCGFILEEGLDMDILERVVASMGKAAREAGVFIVT-GDTKVVPR 135
>2AQV-A nrPDB
Length = 390
Score = 32.7 bits (73), Expect = 0.36, Method: Compositional matrix adjust.
Identities = 18/63 (28%), Positives = 34/63 (53%), Gaps = 2/63 (3%)
Query: 8 LIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGIDTH 67
L++G + + + DVLV +G + A+ ++ P V+D +G+++ PG ID H
Sbjct: 11 LLQGAHLYAPEDRGICDVLVANGKIIAVASNI--PSDIVPNCTVVDLSGQILCPGFIDQH 68
Query: 68 THM 70
H+
Sbjct: 69 VHL 71
>3T8L-A nrPDB
Length = 608
Score = 32.7 bits (73), Expect = 0.37, Method: Compositional matrix adjust.
Identities = 25/67 (37%), Positives = 36/67 (53%), Gaps = 6/67 (8%)
Query: 7 LLIRGGRVVNDDFSEV--ADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGI 64
+LI GG +V+ E+ AD+ G+V AL + P +V+DA G V PG I
Sbjct: 37 VLITGGTLVDVVTGELRPADI----GIVGALIASVHEPASRRDAAQVIDAGGAYVSPGLI 92
Query: 65 DTHTHMQ 71
DTH H++
Sbjct: 93 DTHMHIE 99
>3GIQ-A nrPDB
Length = 480
Score = 32.7 bits (73), Expect = 0.42, Method: Compositional matrix adjust.
Identities = 21/53 (39%), Positives = 27/53 (50%), Gaps = 5/53 (9%)
Query: 23 ADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGIDTHTHMQFPFM 75
AD+ V DG + A+G GA DA+GK+V PG ID H H F+
Sbjct: 27 ADLGVRDGRIAAIGEL-----GAHPARHAWDASGKIVAPGFIDVHGHDDLMFV 74
>4CQD-A nrPDB
Length = 423
Score = 32.0 bits (71), Expect = 0.73, Method: Compositional matrix adjust.
Identities = 13/26 (50%), Positives = 16/26 (61%)
Query: 52 LDAAGKLVLPGGIDTHTHMQFPFMGS 77
+DA G LV PG +D HTHM F +
Sbjct: 65 IDAKGNLVSPGFVDAHTHMDKSFTST 90
>2P9B-A nrPDB
Length = 458
Score = 32.0 bits (71), Expect = 0.76, Method: Compositional matrix adjust.
Identities = 22/61 (36%), Positives = 27/61 (44%), Gaps = 16/61 (26%)
Query: 46 PAGLRVLDAAGKLVLPGGIDTHTHMQFPFMGSRSIDDFHQGT----KAALSGGTTMIIDF 101
PA LD GK+V+PG I+ HTH+ F QG K A G M+ F
Sbjct: 56 PAEYHYLDGTGKIVMPGLINAHTHL------------FSQGKPLNPKLATPKGQRMVATF 103
Query: 102 A 102
A
Sbjct: 104 A 104
>3HPA-A nrPDB
Length = 479
Score = 31.6 bits (70), Expect = 0.87, Method: Compositional matrix adjust.
Identities = 25/72 (34%), Positives = 37/72 (51%), Gaps = 8/72 (11%)
Query: 4 PSRLLIRGGRVV---NDDFSEVAD--VLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKL 58
P LL++ V+ +D E+ D + +ED + A+G P A VLD G L
Sbjct: 28 PKTLLVKHADVLVTMDDTRRELRDAGLYIEDNRIVAVGPSAELPETAD---EVLDLRGHL 84
Query: 59 VLPGGIDTHTHM 70
V+PG ++TH HM
Sbjct: 85 VIPGLVNTHHHM 96
>4CEX-C nrPDB
Length = 570
Score = 31.2 bits (69), Expect = 1.0, Method: Compositional matrix adjust.
Identities = 22/64 (34%), Positives = 28/64 (43%), Gaps = 18/64 (28%)
Query: 23 ADVLVEDGVVRALGHDLLPPGGAP-------------AGLRVLDAAGKLVLPGGIDTHTH 69
AD+ V+DG + +G GG P V+ A GK+V GGIDTH H
Sbjct: 85 ADIGVKDGYIVGIGK-----GGNPDIMDGVTPNMIVGTATEVIAAEGKIVTAGGIDTHVH 139
Query: 70 MQFP 73
P
Sbjct: 140 FINP 143
>3MTW-A nrPDB
Length = 403
Score = 31.2 bits (69), Expect = 1.2, Method: Compositional matrix adjust.
Identities = 22/67 (32%), Positives = 34/67 (50%), Gaps = 9/67 (13%)
Query: 5 SRLL-IRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGG 63
+RLL + G+ V++ V+V DG + ++G PAG +D G +LPG
Sbjct: 9 ARLLDVASGKYVDNPL-----VIVTDGRITSIGK---KGDAVPAGATAVDLPGVTLLPGL 60
Query: 64 IDTHTHM 70
ID H H+
Sbjct: 61 IDMHVHL 67
>2OGJ-A nrPDB
Length = 417
Score = 30.4 bits (67), Expect = 2.1, Method: Compositional matrix adjust.
Identities = 18/48 (37%), Positives = 27/48 (56%), Gaps = 5/48 (10%)
Query: 24 DVLVE-DGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGIDTHTHM 70
D+L+ DG + A+G L APA + +DA G + PG +D H H+
Sbjct: 37 DILIGGDGKIAAVGSALQ----APADTQRIDAKGAFISPGWVDLHVHI 80
>2Y7H-A nrPDB
Length = 464
Score = 30.0 bits (66), Expect = 2.5, Method: Compositional matrix adjust.
Identities = 22/81 (27%), Positives = 34/81 (41%), Gaps = 10/81 (12%)
Query: 353 EDRMSVIWEKGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTR 412
+D + +I + +GK D V V NL +I S DIVI G++
Sbjct: 38 DDYLPLIRANNIQNGKFDTTDLVFVPK-------NLVKESQKI---SPEDIVIAMSSGSK 87
Query: 413 TISAKTHHQAVNFNIFEGMVC 433
++ K+ HQ + F G C
Sbjct: 88 SVVGKSAHQHLPFECSFGAFC 108
>3IGH-X nrPDB
Length = 486
Score = 29.6 bits (65), Expect = 3.1, Method: Compositional matrix adjust.
Identities = 25/92 (27%), Positives = 39/92 (42%), Gaps = 25/92 (27%)
Query: 5 SRLLIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGI 64
S L+I G+V+ SEVA +VE +G ++D GK V+P
Sbjct: 22 SGLVISHGKVIYAGDSEVAKKIVE-----------------LSGGEIVDLKGKYVMPAFF 64
Query: 65 DTHTHM--------QFPFMGSRSIDDFHQGTK 88
D+H H+ G++SI++ Q K
Sbjct: 65 DSHLHLDELGMSLEMVDLRGAKSIEELIQRLK 96
>4LH8-A nrPDB
Length = 469
Score = 29.6 bits (65), Expect = 3.2, Method: Compositional matrix adjust.
Identities = 28/89 (31%), Positives = 45/89 (50%), Gaps = 11/89 (12%)
Query: 7 LLIRG-GRVVNDDFSEV----ADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLP 61
+LIRG RV+ D E AD+L++ + A+G +L + R +D G + LP
Sbjct: 15 ILIRGLTRVITFDDQERELEDADILIDGPKIVAVGKNLSDRSVS----RTIDGRGMIALP 70
Query: 62 GGIDTHTHMQFPFMGSRSIDDFHQGTKAA 90
G I++H H+ M R+I + T A+
Sbjct: 71 GLINSHQHLYEGAM--RAIPQLERVTMAS 97
>3N2C-A nrPDB
Length = 423
Score = 29.6 bits (65), Expect = 3.4, Method: Compositional matrix adjust.
Identities = 14/29 (48%), Positives = 21/29 (72%)
Query: 379 STNAAKIFNLYPRKGRIAVGSDADIVIWD 407
+T AA+I N+ + G IAVG+ AD+V+ D
Sbjct: 353 TTVAAEIVNMQGQLGVIAVGAIADLVVLD 381
>4Z42-C nrPDB
Length = 572
Score = 29.6 bits (65), Expect = 3.5, Method: Compositional matrix adjust.
Identities = 14/37 (37%), Positives = 21/37 (56%)
Query: 373 RFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPK 409
R+VA + N A + G + VG AD+V+WDP+
Sbjct: 407 RYVAKITINPAIAQGVSHVIGSVEVGKMADLVLWDPR 443
>3GGM-A nrPDB
Length = 81
Score = 29.6 bits (65), Expect = 3.5, Method: Composition-based stats.
Identities = 19/66 (28%), Positives = 35/66 (53%), Gaps = 3/66 (4%)
Query: 7 LLIRGGRVVNDDFS--EVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGI 64
+++ G++ D S EV+ + + DG++ A+G D L A + +D K +PG
Sbjct: 6 MILYNGKITTLDPSQPEVSAIAITDGLITAVGGDEL-LNSATEKTKKIDLKRKRAIPGLN 64
Query: 65 DTHTHM 70
D+H H+
Sbjct: 65 DSHIHV 70
>3QGK-C nrPDB
Length = 568
Score = 29.3 bits (64), Expect = 4.0, Method: Compositional matrix adjust.
Identities = 19/63 (30%), Positives = 30/63 (47%), Gaps = 12/63 (19%)
Query: 23 ADVLVEDGVVRALG---HDLLPPGGAP-----AGLRVLDAAGKLVLPGGIDTHTHM---- 70
AD+ +++G + +G + + G P G L G ++ GGID+HTH
Sbjct: 83 ADIGIKNGKIHGIGKAGNKDMQDGVTPHMVVGVGTEALAGEGMIITAGGIDSHTHFLSPQ 142
Query: 71 QFP 73
QFP
Sbjct: 143 QFP 145
>5YGQ-A nrPDB
Length = 342
Score = 29.3 bits (64), Expect = 4.5, Method: Compositional matrix adjust.
Identities = 14/29 (48%), Positives = 19/29 (65%), Gaps = 1/29 (3%)
Query: 439 VTISRGKVVYEAGVFSVTAGDGKFIPRKP 467
VT + GKV +E V V AG G F+P++P
Sbjct: 102 VTTNAGKV-FECTVLVVAAGGGSFLPKRP 129
>1U83-A nrPDB
Length = 276
Score = 29.3 bits (64), Expect = 4.8, Method: Compositional matrix adjust.
Identities = 27/110 (24%), Positives = 40/110 (36%), Gaps = 18/110 (16%)
Query: 160 MFMAYKDLYMVTDLELYEAFSRCKEI----GAIAQVHAENGDLIAEGAKKMLALGITGPE 215
+F Y V + Y + C+ I G + + E IA+ + + L L G +
Sbjct: 102 LFEKYVSQKKVNEFHRYCTYFGCEYIEISNGTLPMTNKEKAAYIADFSDEFLVLSEVGSK 161
Query: 216 GHELCRPEAVEAEATLRAITIASAVNCPLYIVHVMSKSAAKVIADARRDG 265
EL ++ E YIV M A KVI +AR G
Sbjct: 162 DAELASRQSSEEWLE--------------YIVEDMEAGAEKVITEARESG 197
>1YQC-A nrPDB
Length = 170
Score = 28.9 bits (63), Expect = 5.2, Method: Composition-based stats.
Identities = 33/125 (26%), Positives = 46/125 (36%), Gaps = 29/125 (23%)
Query: 217 HELCRPEAVEAEATLRAITIASAVNCPLYIVHVMSKSAAKVIADARRDGKVVY------- 269
H+L E +E + TL +I A N PL I H + + A G+V
Sbjct: 39 HDLALVEILEQDRTLISINRAQPANLPLTI-HELERHPLGTQAFIPMKGEVFVVVVALGD 97
Query: 270 GEPIAASL------GTDGTHYWNKEWHHAAHHVMGPPLRPDPSTPDFLMNLLANDDLTTT 323
+P ++L G G +Y WHH PL DFL +
Sbjct: 98 DKPDLSTLRAFITNGEQGVNYHRNVWHH--------PLFAWQRVTDFLT-------IDRG 142
Query: 324 GTDNC 328
G+DNC
Sbjct: 143 GSDNC 147
>1AK1-A nrPDB
Length = 310
Score = 28.9 bits (63), Expect = 5.4, Method: Compositional matrix adjust.
Identities = 29/99 (29%), Positives = 44/99 (44%), Gaps = 26/99 (26%)
Query: 107 GGSLIEAFETWRSWADPKVCCDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKD 166
GG I + E+W + +PK VT+W D+VKE + +D+ N+ + A+
Sbjct: 137 GGLTITSVESW--YDEPKF---------VTYWVDRVKETYASMPEDERENAMLIVSAHS- 184
Query: 167 LYMVTDLELYEAFSRCKEIG--AIAQVHAENGDLIAEGA 203
+ KE G Q+H E+ LIAEGA
Sbjct: 185 -----------LPEKIKEFGDPYPDQLH-ESAKLIAEGA 211
>2PLM-A nrPDB
Length = 406
Score = 28.9 bits (63), Expect = 6.4, Method: Compositional matrix adjust.
Identities = 11/18 (61%), Positives = 14/18 (77%)
Query: 52 LDAAGKLVLPGGIDTHTH 69
LD +GKLV+P +THTH
Sbjct: 40 LDLSGKLVMPALFNTHTH 57
>3ICJ-A nrPDB
Length = 534
Score = 28.5 bits (62), Expect = 7.4, Method: Compositional matrix adjust.
Identities = 12/35 (34%), Positives = 18/35 (51%)
Query: 47 AGLRVLDAAGKLVLPGGIDTHTHMQFPFMGSRSID 81
AG ++D GK V+P D+H H+ M +D
Sbjct: 81 AGGEIIDLKGKFVMPAFFDSHLHLDELGMSLEMVD 115
>2GBX-B nrPDB
Length = 174
Score = 28.5 bits (62), Expect = 8.3, Method: Compositional matrix adjust.
Identities = 14/35 (40%), Positives = 19/35 (54%)
Query: 472 IYKRIKQRDRTCTPTPVERAPYKGEVATLKSRVTK 506
IY++ RDR PTP + A Y + LK RV +
Sbjct: 50 IYEQRLTRDRRPDPTPDDAAIYNDDFGELKQRVER 84
>2OOD-A nrPDB
Length = 475
Score = 28.1 bits (61), Expect = 8.9, Method: Compositional matrix adjust.
Identities = 15/52 (28%), Positives = 27/52 (51%), Gaps = 1/52 (1%)
Query: 19 FSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGIDTHTHM 70
F + ++V DGV++A G A G+ + ++++PG ID H H+
Sbjct: 32 FHQDGLMVVTDGVIKAFG-PYEKIAAAHPGVEITHIKDRIIVPGFIDGHIHL 82
Searching..................................................done
Results from round 2
Score E
Sequences producing significant alignments: (bits) Value
Sequences used in model and found again:
2VR2-A nrPDB 790 0.0
5YZA-A nrPDB 737 0.0
4CNT-A nrPDB 728 0.0
4LCQ-A nrPDB 719 0.0
1KCX-A nrPDB 712 0.0
5NKS-A nrPDB 701 0.0
4CNS-A nrPDB 694 0.0
2FTW-A nrPDB 689 0.0
4B90-A nrPDB 683 0.0
4TQT-A nrPDB 655 0.0
3DC8-A nrPDB 652 0.0
6AJD-A nrPDB 650 0.0
4B91-A nrPDB 645 0.0
1YNY-A nrPDB 623 e-179
1K1D-A nrPDB 621 e-178
3SFW-A nrPDB 621 e-178
1GKQ-A nrPDB 566 e-161
1NFG-A nrPDB 530 e-151
2FTY-A nrPDB 481 e-136
1GKR-A nrPDB 464 e-131
3E74-A nrPDB 455 e-128
3HM7-A nrPDB 438 e-123
3MPG-A nrPDB 423 e-118
3GRI-A nrPDB 419 e-117
2GWN-A nrPDB 411 e-115
1XRT-A nrPDB 369 e-102
2Z00-A nrPDB 349 2e-96
6HG1-A nrPDB 226 2e-59
2VUN-A nrPDB 90 3e-18
Sequences not found previously or not previously below threshold:
3OOQ-A nrPDB 102 4e-22
3GIQ-A nrPDB 87 2e-17
2PUZ-A nrPDB 84 1e-16
1FWC-C nrPDB 79 7e-15
1RK6-A nrPDB 76 5e-14
3QGK-C nrPDB 75 6e-14
2VHL-A nrPDB 74 2e-13
4CEX-C nrPDB 74 2e-13
2ICS-A nrPDB 69 5e-12
4WGX-A nrPDB 68 9e-12
1E9Y-B nrPDB 65 5e-11
4CQD-A nrPDB 65 9e-11
2AQV-A nrPDB 64 1e-10
2OGJ-A nrPDB 64 2e-10
3MKV-A nrPDB 64 2e-10
3IV8-A nrPDB 62 6e-10
3HPA-A nrPDB 61 1e-09
2PLM-A nrPDB 61 1e-09
3DUG-A nrPDB 61 1e-09
4Z42-C nrPDB 60 2e-09
4V1Y-A nrPDB 59 6e-09
3T8L-A nrPDB 57 1e-08
2BB0-A nrPDB 57 3e-08
5T5I-A nrPDB 56 3e-08
4H9M-A nrPDB 56 5e-08
4R7W-A nrPDB 55 5e-08
5XGX-A nrPDB 55 7e-08
1O12-A nrPDB 55 7e-08
5VGM-A nrPDB 55 9e-08
4G7E-B nrPDB 54 1e-07
3N2C-A nrPDB 53 4e-07
4DYK-A nrPDB 52 6e-07
4LH8-A nrPDB 52 6e-07
4F0R-A nrPDB 52 8e-07
4WHB-E nrPDB 51 1e-06
3MTW-A nrPDB 50 2e-06
6NBO-A nrPDB 48 1e-05
1YRR-A nrPDB 45 6e-05
2OOF-A nrPDB 45 7e-05
3GGM-A nrPDB 45 1e-04
3IGH-X nrPDB 44 2e-04
4LFY-A nrPDB 43 3e-04
3ICJ-A nrPDB 43 3e-04
2QS8-A nrPDB 43 4e-04
1R9X-A nrPDB 43 4e-04
2P9B-A nrPDB 42 6e-04
3LNP-A nrPDB 42 8e-04
4DZH-A nrPDB 40 0.002
6CTY-A nrPDB 40 0.002
3JZE-A nrPDB 40 0.003
2OOD-A nrPDB 38 0.012
3MDW-A nrPDB 37 0.027
2I9U-A nrPDB 36 0.038
2PAJ-A nrPDB 36 0.051
2WJF-A nrPDB 35 0.066
6FV3-A nrPDB 34 0.20
5YDJ-A nrPDB 33 0.37
5YDI-A nrPDB 33 0.37
6NRZ-A nrPDB 33 0.39
5JCN-A nrPDB 32 0.47
1S69-A nrPDB 32 0.58
2QIW-A nrPDB 32 0.86
3RZZ-A nrPDB 31 1.5
6ERI-Ad nrPDB 30 2.2
5MLC-5 nrPDB 30 2.2
1Z72-A nrPDB 30 2.8
2QI2-A nrPDB 30 3.4
4WVX-A nrPDB 30 3.4
2OI8-A nrPDB 30 3.5
2YFK-A nrPDB 29 4.7
5WLC-LV nrPDB 29 5.1
1AOS-A nrPDB 29 8.2
>2VR2-A nrPDB
Length = 541
Score = 790 bits (2040), Expect = 0.0, Method: Composition-based stats.
Identities = 519/519 (100%), Positives = 519/519 (100%)
Query: 1 MAAPSRLLIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVL 60
MAAPSRLLIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVL
Sbjct: 23 MAAPSRLLIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVL 82
Query: 61 PGGIDTHTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSW 120
PGGIDTHTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSW
Sbjct: 83 PGGIDTHTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSW 142
Query: 121 ADPKVCCDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEAFS 180
ADPKVCCDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEAFS
Sbjct: 143 ADPKVCCDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEAFS 202
Query: 181 RCKEIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAV 240
RCKEIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAV
Sbjct: 203 RCKEIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAV 262
Query: 241 NCPLYIVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMGPP 300
NCPLYIVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMGPP
Sbjct: 263 NCPLYIVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMGPP 322
Query: 301 LRPDPSTPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIW 360
LRPDPSTPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIW
Sbjct: 323 LRPDPSTPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIW 382
Query: 361 EKGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTHH 420
EKGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTHH
Sbjct: 383 EKGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTHH 442
Query: 421 QAVNFNIFEGMVCHGVPLVTISRGKVVYEAGVFSVTAGDGKFIPRKPFAEYIYKRIKQRD 480
QAVNFNIFEGMVCHGVPLVTISRGKVVYEAGVFSVTAGDGKFIPRKPFAEYIYKRIKQRD
Sbjct: 443 QAVNFNIFEGMVCHGVPLVTISRGKVVYEAGVFSVTAGDGKFIPRKPFAEYIYKRIKQRD 502
Query: 481 RTCTPTPVERAPYKGEVATLKSRVTKEDATAGTRKQAHP 519
RTCTPTPVERAPYKGEVATLKSRVTKEDATAGTRKQAHP
Sbjct: 503 RTCTPTPVERAPYKGEVATLKSRVTKEDATAGTRKQAHP 541
>5YZA-A nrPDB
Length = 525
Score = 737 bits (1902), Expect = 0.0, Method: Composition-based stats.
Identities = 308/516 (59%), Positives = 385/516 (74%), Gaps = 6/516 (1%)
Query: 4 PSRLLIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGG 63
RLLI+GG++VNDD S AD+ +EDG+++ +G +L+ PGG ++ ++A ++V+PGG
Sbjct: 14 SDRLLIKGGKIVNDDQSFYADIYMEDGLIKQIGENLIVPGG----VKTIEAHSRMVIPGG 69
Query: 64 IDTHTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWADP 123
ID HT Q P G S DDF QGTKAAL+GGTTMIID +P+ G SL+ AF+ WR WAD
Sbjct: 70 IDVHTRFQMPDQGMTSADDFFQGTKAALAGGTTMIIDHVVPEPGTSLLAAFDQWREWADS 129
Query: 124 KVCCDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEAFSRCK 183
K CCDYSLHV ++ W ++EEM+ LV+D GVNSF ++MA+KD + +TD ++YE S +
Sbjct: 130 KSCCDYSLHVDISEWHKGIQEEMEALVKDHGVNSFLVYMAFKDRFQLTDCQIYEVLSVIR 189
Query: 184 EIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAVNCP 243
+IGAIAQVHAENGD+IAE +++L LGITGPEGH L RPE VEAEA RAITIA+ NCP
Sbjct: 190 DIGAIAQVHAENGDIIAEEQQRILDLGITGPEGHVLSRPEEVEAEAVNRAITIANQTNCP 249
Query: 244 LYIVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMGPPLRP 303
LYI VMSKS+A+VIA AR+ G VVYGEPI ASLGTDG+HYW+K W AA V PPL P
Sbjct: 250 LYITKVMSKSSAEVIAQARKKGTVVYGEPITASLGTDGSHYWSKNWAKAAAFVTSPPLSP 309
Query: 304 DPSTPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIWEKG 363
DP+TPDFL +LL+ DL TG+ +CTFNT QKA+GKD+FT IP G NG E+RMSVIW+K
Sbjct: 310 DPTTPDFLNSLLSCGDLQVTGSAHCTFNTAQKAVGKDNFTLIPEGTNGTEERMSVIWDKA 369
Query: 364 VHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTHHQAV 423
V +GKMDEN+FVAVTSTNAAK+FNLYPRKGRIAVGSDAD+VIWDP +TISAKTH+ ++
Sbjct: 370 VVTGKMDENQFVAVTSTNAAKVFNLYPRKGRIAVGSDADLVIWDPDSVKTISAKTHNSSL 429
Query: 424 NFNIFEGMVCHGVPLVTISRGKVVYEAGVFSVTAGDGKFIPRKPFAEYIYKRIKQRDRTC 483
+NIFEGM C G PLV IS+GK+V E G VT G G++IPRKPF +++YKRIK R R
Sbjct: 430 EYNIFEGMECRGSPLVVISQGKIVLEDGTLHVTEGSGRYIPRKPFPDFVYKRIKARSRLA 489
Query: 484 TPTPVERAPYKGEVATLKSRVTKEDATAGTRKQAHP 519
V R Y G V + VT + T + + P
Sbjct: 490 ELRGVPRGLYDGPVCEVS--VTPKTVTPASSAKTDP 523
>4CNT-A nrPDB
Length = 570
Score = 728 bits (1879), Expect = 0.0, Method: Composition-based stats.
Identities = 303/516 (58%), Positives = 383/516 (74%), Gaps = 6/516 (1%)
Query: 4 PSRLLIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGG 63
RLLI+GGR+VNDD S AD+ +EDG+++ +G +L+ PGG ++ ++A GK+V+PGG
Sbjct: 14 SDRLLIKGGRIVNDDQSFYADIYMEDGLIKQIGDNLIVPGG----VKTIEANGKMVIPGG 69
Query: 64 IDTHTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWADP 123
ID HTH Q P+ G ++DDF QGTKAAL+GGTTMIID +P+ SL EA+E WR WAD
Sbjct: 70 IDVHTHYQMPYKGMTTVDDFFQGTKAALAGGTTMIIDHVVPEPESSLTEAYEKWREWADG 129
Query: 124 KVCCDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEAFSRCK 183
K CCDY+LHV +T W+D VK+E++ L++DKGVNSF ++MAYKDLY V++ ELYE F+
Sbjct: 130 KSCCDYALHVDITHWNDSVKQEVQNLIKDKGVNSFMVYMAYKDLYQVSNTELYEIFTCLG 189
Query: 184 EIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAVNCP 243
E+GAIAQVHAENGD+IA+ +ML +GITGPEGH L RPE +EAEA RAITIAS NCP
Sbjct: 190 ELGAIAQVHAENGDIIAQEQTRMLEMGITGPEGHVLSRPEELEAEAVFRAITIASQTNCP 249
Query: 244 LYIVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMGPPLRP 303
LY+ VMSKSAA +I+ AR+ G VV+GEPI ASLG DGTHYW+K W AA V PPL P
Sbjct: 250 LYVTKVMSKSAADLISQARKKGNVVFGEPITASLGIDGTHYWSKNWAKAAAFVTSPPLSP 309
Query: 304 DPSTPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIWEKG 363
DP+TPD++ +LLA+ DL +G+ +CTF+T QKA+GKD+FT IP G NGVE+RMSVIW+K
Sbjct: 310 DPTTPDYINSLLASGDLQLSGSAHCTFSTAQKAIGKDNFTAIPEGTNGVEERMSVIWDKA 369
Query: 364 VHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTHHQAV 423
V +GKMDEN+FVAVTSTNAAKIFNLYPRKGRI+VGSD+D+VIWDP + +SAK H A
Sbjct: 370 VATGKMDENQFVAVTSTNAAKIFNLYPRKGRISVGSDSDLVIWDPDAVKIVSAKNHQSAA 429
Query: 424 NFNIFEGMVCHGVPLVTISRGKVVYEAGVFSVTAGDGKFIPRKPFAEYIYKRIKQRDRTC 483
+NIFEGM G PLV I +GK++ E G VT G G+FIP PF++Y+YKRIK R +
Sbjct: 430 EYNIFEGMELRGAPLVVICQGKIMLEDGNLHVTQGAGRFIPCSPFSDYVYKRIKARRKMA 489
Query: 484 TPTPVERAPYKGEVATLKSRVTKEDATAGTRKQAHP 519
V R Y G V L + T + T + P
Sbjct: 490 DLHAVPRGMYDGPVFDLTT--TPKGGTPAGSARGSP 523
>4LCQ-A nrPDB
Length = 520
Score = 719 bits (1856), Expect = 0.0, Method: Composition-based stats.
Identities = 368/502 (73%), Positives = 429/502 (85%), Gaps = 4/502 (0%)
Query: 1 MAAPSRLLIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVL 60
MA +LI+GG+VVN+D S +DV + G + +G DL P GA RV+DA +LV+
Sbjct: 21 MAEAGEILIKGGKVVNEDCSFFSDVHIRGGKIVEVGPDLRVPPGA----RVIDATDRLVI 76
Query: 61 PGGIDTHTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSW 120
PGGIDTHTHM+ FMG+R++DDFH GTKAAL+GGTTMI+DF + QKG SL+EA++ WR
Sbjct: 77 PGGIDTHTHMELAFMGTRAVDDFHIGTKAALAGGTTMILDFVMTQKGQSLLEAYDLWRKT 136
Query: 121 ADPKVCCDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEAFS 180
ADPKVCCDYSLHVAVTWWSD+VK+EM+ L Q++GVNSFKMFMAYK L+M+ D ELY FS
Sbjct: 137 ADPKVCCDYSLHVAVTWWSDEVKDEMRTLAQERGVNSFKMFMAYKGLFMLRDDELYAVFS 196
Query: 181 RCKEIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAV 240
CKE+GAIAQVHAENGDLIAEGAKKML+LGITGPEGHELCRPEAVEAEAT RAITIASAV
Sbjct: 197 HCKEVGAIAQVHAENGDLIAEGAKKMLSLGITGPEGHELCRPEAVEAEATQRAITIASAV 256
Query: 241 NCPLYIVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMGPP 300
NCPLY+VHVMSKSAA V++ AR+DG+VV+GEPIAASLGTDGT+YW+K+W HAA +VMGPP
Sbjct: 257 NCPLYVVHVMSKSAADVVSKARKDGRVVFGEPIAASLGTDGTNYWHKDWAHAAQYVMGPP 316
Query: 301 LRPDPSTPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIW 360
LRPDPSTP +LM+LLANDDLT TGTDNCTF+ CQKALGKDDFT+IPNGVNGVEDRMSVIW
Sbjct: 317 LRPDPSTPGYLMDLLANDDLTLTGTDNCTFSRCQKALGKDDFTRIPNGVNGVEDRMSVIW 376
Query: 361 EKGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTHH 420
EKGVHSGKMDENRFVAVTS+NAAKIFN YP+KGRIA SDAD+VIWDPK TR ISA+THH
Sbjct: 377 EKGVHSGKMDENRFVAVTSSNAAKIFNFYPQKGRIAKDSDADVVIWDPKTTRKISAQTHH 436
Query: 421 QAVNFNIFEGMVCHGVPLVTISRGKVVYEAGVFSVTAGDGKFIPRKPFAEYIYKRIKQRD 480
QAV++NIFEGM CHGVP+VT+SRG+VVYE G V+ G G+FI R+PF+E++YKRI+QRD
Sbjct: 437 QAVDYNIFEGMECHGVPVVTVSRGRVVYEEGRLKVSPGQGRFIHRQPFSEFVYKRIRQRD 496
Query: 481 RTCTPTPVERAPYKGEVATLKS 502
P V R PY GEV L +
Sbjct: 497 EVGKPAVVIREPYAGEVVALGT 518
>1KCX-A nrPDB
Length = 518
Score = 712 bits (1837), Expect = 0.0, Method: Composition-based stats.
Identities = 304/516 (58%), Positives = 390/516 (75%), Gaps = 6/516 (1%)
Query: 4 PSRLLIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGG 63
RLLIRGGR++NDD S ADV +EDG+++ +G +L+ PGG ++ ++A G++V+PGG
Sbjct: 7 SDRLLIRGGRIINDDQSFYADVYLEDGLIKQIGENLIVPGG----VKTIEANGRMVIPGG 62
Query: 64 IDTHTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWADP 123
ID +T++Q P G S DDF QGTKAAL+GGTTMIID +P+ G SL+ +FE W AD
Sbjct: 63 IDVNTYLQKPSQGMTSADDFFQGTKAALAGGTTMIIDHVVPEPGSSLLTSFEKWHEAADT 122
Query: 124 KVCCDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEAFSRCK 183
K CCDYSLHV +T W D V+EE+++LVQDKGVNSF+++MAYKDLY ++D +LYEAF+ K
Sbjct: 123 KSCCDYSLHVDITSWYDGVREELEVLVQDKGVNSFQVYMAYKDLYQMSDSQLYEAFTFLK 182
Query: 184 EIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAVNCP 243
+GA+ VHAENGDLIA+ K++L +GITGPEGH L RPE +EAEA RAI IA +NCP
Sbjct: 183 GLGAVILVHAENGDLIAQEQKRILEMGITGPEGHALSRPEELEAEAVFRAIAIAGRINCP 242
Query: 244 LYIVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMGPPLRP 303
+YI VMSKSAA +IA AR+ G +V+GEPIAASLGTDGTHYW+K W AA V PPL P
Sbjct: 243 VYITKVMSKSAADIIALARKKGPLVFGEPIAASLGTDGTHYWSKNWAKAAAFVTSPPLSP 302
Query: 304 DPSTPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIWEKG 363
DP+TPD+L +LLA DL TG+ +C ++T QKA+GKD+FT IP GVNG+E+RM+V+W+K
Sbjct: 303 DPTTPDYLTSLLACGDLQVTGSGHCPYSTAQKAVGKDNFTLIPEGVNGIEERMTVVWDKA 362
Query: 364 VHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTHHQAV 423
V +GKMDEN+FVAVTSTNAAKIFNLYPRKGRIAVGSDAD+VIWDP +TI+AK+H V
Sbjct: 363 VATGKMDENQFVAVTSTNAAKIFNLYPRKGRIAVGSDADVVIWDPDKMKTITAKSHKSTV 422
Query: 424 NFNIFEGMVCHGVPLVTISRGKVVYEAGVFSVTAGDGKFIPRKPFAEYIYKRIKQRDRTC 483
+NIFEGM CHG PLV IS+GK+V+E G SV+ G G+FIPRKPF E++Y+R++ R +
Sbjct: 423 EYNIFEGMECHGSPLVVISQGKIVFEDGNISVSKGMGRFIPRKPFPEHLYQRVRIRSKVF 482
Query: 484 TPTPVERAPYKGEVATLKSRVTKEDATAGTRKQAHP 519
V R Y G V + T + A ++ P
Sbjct: 483 GLHSVSRGMYDGPVYEV--PATPKHAAPAPSAKSSP 516
>5NKS-A nrPDB
Length = 573
Score = 701 bits (1810), Expect = 0.0, Method: Composition-based stats.
Identities = 292/509 (57%), Positives = 363/509 (71%), Gaps = 4/509 (0%)
Query: 4 PSRLLIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGG 63
RLLIRGGR+VNDD S ADV VEDG+++ +G +L+ PGG ++ +DA G +VLPGG
Sbjct: 15 SDRLLIRGGRIVNDDQSFYADVHVEDGLIKQIGENLIVPGG----IKTIDAHGLMVLPGG 70
Query: 64 IDTHTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWADP 123
+D HT +Q P +G DDF QGTKAAL+GGTTMI+D P G SL+ A+E WR AD
Sbjct: 71 VDVHTRLQMPVLGMTPADDFCQGTKAALAGGTTMILDHVFPDTGVSLLAAYEQWRERADS 130
Query: 124 KVCCDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEAFSRCK 183
CCDYSLHV +T W + +KEE++ LV++KGVNSF +FMAYKD +D ++YE FS +
Sbjct: 131 AACCDYSLHVDITRWHESIKEELEALVKEKGVNSFLVFMAYKDRCQCSDSQMYEIFSIIR 190
Query: 184 EIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAVNCP 243
++GA+AQVHAENGD++ E K++L LGITGPEGH L PE VEAEA RA+TIA NCP
Sbjct: 191 DLGALAQVHAENGDIVEEEQKRLLELGITGPEGHVLSHPEEVEAEAVYRAVTIAKQANCP 250
Query: 244 LYIVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMGPPLRP 303
LY+ VMSK AA IA A+R G VV+GEPI ASLGTDG+HYW+K W AA V PP+ P
Sbjct: 251 LYVTKVMSKGAADAIAQAKRRGVVVFGEPITASLGTDGSHYWSKNWAKAAAFVTSPPVNP 310
Query: 304 DPSTPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIWEKG 363
DP+T D L LL++ DL TG+ +CTF T QKA+GKD+F IP G NG+E+RMS++WEK
Sbjct: 311 DPTTADHLTCLLSSGDLQVTGSAHCTFTTAQKAVGKDNFALIPEGTNGIEERMSMVWEKC 370
Query: 364 VHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTHHQAV 423
V SGKMDEN FVAVTSTNAAKIFN YPRKGR+AVGSDAD+VIW+PK T+ ISAKTH+ V
Sbjct: 371 VASGKMDENEFVAVTSTNAAKIFNFYPRKGRVAVGSDADLVIWNPKATKIISAKTHNLNV 430
Query: 424 NFNIFEGMVCHGVPLVTISRGKVVYEAGVFSVTAGDGKFIPRKPFAEYIYKRIKQRDRTC 483
+NIFEG+ C G P V IS+G+V E G VT G G+F+PRK F +++YKRIK R+R
Sbjct: 431 EYNIFEGVECRGAPAVVISQGRVALEDGKMFVTPGAGRFVPRKTFPDFVYKRIKARNRLA 490
Query: 484 TPTPVERAPYKGEVATLKSRVTKEDATAG 512
V R Y G V +
Sbjct: 491 EIHGVPRGLYDGPVHEVMVPAKPGSGAPA 519
>4CNS-A nrPDB
Length = 480
Score = 694 bits (1790), Expect = 0.0, Method: Composition-based stats.
Identities = 294/481 (61%), Positives = 371/481 (77%), Gaps = 4/481 (0%)
Query: 4 PSRLLIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGG 63
RLLI+GGR+VNDD S AD+ +EDG+++ +G +L+ PGG ++ ++A GK+V+PGG
Sbjct: 4 SDRLLIKGGRIVNDDQSFYADIYMEDGLIKQIGDNLIVPGG----VKTIEANGKMVIPGG 59
Query: 64 IDTHTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWADP 123
ID HTH Q P+ G ++DDF QGTKAAL+GGTTMIID +P+ SL EA+E WR WAD
Sbjct: 60 IDVHTHYQMPYKGMTTVDDFFQGTKAALAGGTTMIIDHVVPEPESSLTEAYEKWREWADG 119
Query: 124 KVCCDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEAFSRCK 183
K CCDY+LHV +T W+D VK+E++ L++DKGVNSF ++MAYKDLY V++ ELYE F+
Sbjct: 120 KSCCDYALHVDITHWNDSVKQEVQNLIKDKGVNSFMVYMAYKDLYQVSNTELYEIFTCLG 179
Query: 184 EIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAVNCP 243
E+GAIAQVHAENGD+IA+ +ML +GITGPEGH L RPE +EAEA RAITIAS NCP
Sbjct: 180 ELGAIAQVHAENGDIIAQEQTRMLEMGITGPEGHVLSRPEELEAEAVFRAITIASQTNCP 239
Query: 244 LYIVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMGPPLRP 303
LY+ VMSKSAA +I+ AR+ G VV+GEPI ASLG DGTHYW+K W AA V PPL P
Sbjct: 240 LYVTKVMSKSAADLISQARKKGNVVFGEPITASLGIDGTHYWSKNWAKAAAFVTSPPLSP 299
Query: 304 DPSTPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIWEKG 363
DP+TPD++ +LLA+ DL +G+ +CTF+T QKA+GKD+FT IP G NGVE+RMSVIW+K
Sbjct: 300 DPTTPDYINSLLASGDLQLSGSAHCTFSTAQKAIGKDNFTAIPEGTNGVEERMSVIWDKA 359
Query: 364 VHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTHHQAV 423
V +GKMDEN+FVAVTSTNAAKIFNLYPRKGRI+VGSD+D+VIWDP + +SAK H A
Sbjct: 360 VATGKMDENQFVAVTSTNAAKIFNLYPRKGRISVGSDSDLVIWDPDAVKIVSAKNHQSAA 419
Query: 424 NFNIFEGMVCHGVPLVTISRGKVVYEAGVFSVTAGDGKFIPRKPFAEYIYKRIKQRDRTC 483
+NIFEGM G PLV I +GK++ E G VT G G+FIP PF++Y+YKRIK R +
Sbjct: 420 EYNIFEGMELRGAPLVVICQGKIMLEDGNLHVTQGAGRFIPCSPFSDYVYKRIKARRKMA 479
Query: 484 T 484
Sbjct: 480 D 480
>2FTW-A nrPDB
Length = 521
Score = 689 bits (1777), Expect = 0.0, Method: Composition-based stats.
Identities = 294/496 (59%), Positives = 366/496 (73%), Gaps = 7/496 (1%)
Query: 3 APSRLLIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPG 62
+LI+ G VVNDD +DVLVE+G+++ + ++ P G ++V+DA KL+LPG
Sbjct: 6 QTGTILIKNGTVVNDDRYFKSDVLVENGIIKEISKNIEPKEG----IKVVDATDKLLLPG 61
Query: 63 GIDTHTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWAD 122
GIDTHTH Q PFMG+ S+DDF GT+AA++GGTT IIDF IP +G SL+EA++ W+ WAD
Sbjct: 62 GIDTHTHFQLPFMGTVSVDDFDIGTQAAVAGGTTFIIDFVIPTRGQSLLEAYDQWKKWAD 121
Query: 123 PKVCCDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEAFSRC 182
KV CDYSLHVA+TWWS+QV EM+ILV+++GVNSFK FMAYK+ +MVTD E+Y F RC
Sbjct: 122 EKVNCDYSLHVAITWWSEQVSREMEILVKERGVNSFKCFMAYKNSFMVTDQEMYHIFKRC 181
Query: 183 KEIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAVNC 242
KE+GAIAQVHAENGD++ EG KKML +GITGPEGHEL RPEA+EAEAT RAI IA +V
Sbjct: 182 KELGAIAQVHAENGDMVFEGQKKMLEMGITGPEGHELSRPEALEAEATNRAIVIADSVCT 241
Query: 243 PLYIVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMGPPLR 302
P+YIVHV S AA VI R++G VYGEPIAA LG DG+H WN +W HAA VMGPP+R
Sbjct: 242 PVYIVHVQSIGAADVICKHRKEGVRVYGEPIAAGLGVDGSHMWNHDWRHAAAFVMGPPIR 301
Query: 303 PDPSTPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIWEK 362
PDP T LM+ LA DL GTDNCTF QKA+GKDDFTKIPNGVNGVEDRMS++WE
Sbjct: 302 PDPRTKGVLMDYLARGDLDCVGTDNCTFCADQKAMGKDDFTKIPNGVNGVEDRMSIVWEN 361
Query: 363 GVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTHHQA 422
GV++GK+ +FV TS+ A+IFN+YPRKGRI VG D DIVIWDP ++TIS THH A
Sbjct: 362 GVNTGKLTWCQFVRATSSERARIFNIYPRKGRIDVGCDGDIVIWDPNQSKTISKDTHHHA 421
Query: 423 VNFNIFEGMVCHGVPLVTISRGKVVYEAGVFSVTAGDGKFIPRKPFAEYIYKRIKQRD-- 480
V+FNIFEG+ G+ + TI G +V+ S G G+F+PR PF ++ I+QRD
Sbjct: 422 VDFNIFEGIKVTGIAVTTIVAGNIVWSDNKLSCVKGSGRFVPRPPFGP-VFDGIEQRDKV 480
Query: 481 RTCTPTPVERAPYKGE 496
R V+R PY+ +
Sbjct: 481 RNELLRKVDRKPYEDD 496
>4B90-A nrPDB
Length = 586
Score = 683 bits (1762), Expect = 0.0, Method: Composition-based stats.
Identities = 298/518 (57%), Positives = 381/518 (73%), Gaps = 4/518 (0%)
Query: 2 AAPSRLLIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLP 61
+A R+LI+GG+VVNDD + ADV +E+G+++ +G +L+ PGGA +V+DA GKLV+P
Sbjct: 27 SASVRILIKGGKVVNDDCTHEADVYIENGIIQQVGRELMIPGGA----KVIDATGKLVIP 82
Query: 62 GGIDTHTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWA 121
GGIDT TH FM + +DDF+ GTKAAL GGTTMII +P K SL++A+E R A
Sbjct: 83 GGIDTSTHFHQTFMNATCVDDFYHGTKAALVGGTTMIIGHVLPDKETSLVDAYEKCRGLA 142
Query: 122 DPKVCCDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEAFSR 181
DPKVCCDY+LHV +TWW+ +VK EM+ LV++KGVNSF+MFM YKDLYM+ D ELY+
Sbjct: 143 DPKVCCDYALHVGITWWAPKVKAEMETLVREKGVNSFQMFMTYKDLYMLRDSELYQVLHA 202
Query: 182 CKEIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAVN 241
CK+IGAIA+VHAENG+L+AEGAK+ L LGITGPEG E+ RPE +EAEAT R ITIA+ +
Sbjct: 203 CKDIGAIARVHAENGELVAEGAKEALDLGITGPEGIEISRPEELEAEATHRVITIANRTH 262
Query: 242 CPLYIVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMGPPL 301
CP+Y+V+V S SA VIA A+ GKVV E A G HY++++W HAA +V PPL
Sbjct: 263 CPIYLVNVSSISAGDVIAAAKMQGKVVLAETTTAHATLTGLHYYHQDWSHAAAYVTVPPL 322
Query: 302 RPDPSTPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIWE 361
R D +T +LM+LLAND L +D+ F T QKA+GK+DFTKIP+GV+GV+DRMSVIWE
Sbjct: 323 RLDTNTSTYLMSLLANDTLNIVASDHRPFTTKQKAMGKEDFTKIPHGVSGVQDRMSVIWE 382
Query: 362 KGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTHHQ 421
+GV GKMDENRFVAVTS+NAAK+ NLYPRKGRI G+DAD+V+WDP+ T+TISA T Q
Sbjct: 383 RGVVGGKMDENRFVAVTSSNAAKLLNLYPRKGRIIPGADADVVVWDPEATKTISASTQVQ 442
Query: 422 AVNFNIFEGMVCHGVPLVTISRGKVVYEAGVFSVTAGDGKFIPRKPFAEYIYKRIKQRDR 481
+FN++E M CHGVPLVTISRG+VVYE GVF G GKF P + F + +YK++ QR++
Sbjct: 443 GGDFNLYENMRCHGVPLVTISRGRVVYENGVFMCAEGTGKFCPLRSFPDTVYKKLVQREK 502
Query: 482 TCTPTPVERAPYKGEVATLKSRVTKEDATAGTRKQAHP 519
T V+R PY G+VA + KE T P
Sbjct: 503 TLKVRGVDRTPYLGDVAVVVHPGKKEMGTPLADTPTRP 540
>4TQT-A nrPDB
Length = 497
Score = 655 bits (1690), Expect = 0.0, Method: Composition-based stats.
Identities = 224/490 (45%), Positives = 313/490 (63%), Gaps = 11/490 (2%)
Query: 8 LIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGIDTH 67
+I+GG V+ D + AD+L+EDG + A+G L G V+DA+G V+PGGID H
Sbjct: 17 VIKGGTVITADRTFRADILIEDGKIAAIGDSL-------EGDEVIDASGCYVMPGGIDPH 69
Query: 68 THMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWADPKVCC 127
TH+Q PFMG+ S DDF GT AAL+GGTTM++DF +P G+L++A + W A K
Sbjct: 70 THLQMPFMGTYSSDDFDTGTAAALAGGTTMVVDFVLPDSEGNLLDALQEWFQKA-GKART 128
Query: 128 DYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEAFSRCKEIGA 187
DYS H+A+T W+++ EM +V+ +G+N+FK FMAYK MV D E++ +F RC E+GA
Sbjct: 129 DYSFHMAITGWNERTFNEMAEVVK-RGINTFKHFMAYKGALMVNDDEMFASFQRCAELGA 187
Query: 188 IAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAVNCPLYIV 247
+ VHAENGD++A+ K++A G GPE H RP VE EAT RAI IA PLY+V
Sbjct: 188 MPLVHAENGDIVAQLQAKLMAEGNDGPEAHAYSRPPEVEGEATNRAIMIADQAGVPLYVV 247
Query: 248 HVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMGPPLRPDPST 307
HV + + + I AR+ G V+GEP+ L D + Y N++W +AA VM PP R D
Sbjct: 248 HVSCEQSHEAIRRARQKGMRVFGEPLIQHLTLDESEYHNRDWDYAARRVMSPPFR-DKLN 306
Query: 308 PDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIWEKGVHSG 367
D L LA L TD+C F T QK G +FTKIPNG G+E+RM V+W +GV +G
Sbjct: 307 QDSLWAGLAAGSLQCVATDHCAFTTEQKRYGIGNFTKIPNGTGGLEERMPVLWTRGVRTG 366
Query: 368 KMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTHHQAVNFNI 427
++ N FVAVTSTN AKI N+YP+KG + G+DAD+VIWDP+ T+ ISAKT H ++++N+
Sbjct: 367 RLTPNEFVAVTSTNIAKILNIYPQKGAVVPGADADLVIWDPETTKKISAKTQHSSIDYNV 426
Query: 428 FEGMVCHGVPLVTISRGKVVYEAGVFSVTAGDGKFIPRKPFAEYIYKRIKQRDRTCTPTP 487
FEG G+P++T+SRG++ ++ G + GDG+FI R+P + + + Q P
Sbjct: 427 FEGFELKGLPIMTLSRGRIAFDKGQVTAKPGDGRFIEREPNGA-VNRALSQWKEIVAPRK 485
Query: 488 VERAPYKGEV 497
VER+ +
Sbjct: 486 VERSAEHMPI 495
>3DC8-A nrPDB
Length = 490
Score = 652 bits (1681), Expect = 0.0, Method: Composition-based stats.
Identities = 230/485 (47%), Positives = 307/485 (63%), Gaps = 10/485 (2%)
Query: 7 LLIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGIDT 66
+I+GG +V D + ADV VE G + +G +L +G LDA G V+PGGID
Sbjct: 3 TVIKGGTIVTADLTYKADVKVEGGRIVEIGPNL-------SGAETLDATGCYVMPGGIDP 55
Query: 67 HTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWADPKVC 126
HTH++ PFMG+ S DDF GT+AAL+GGTTM++DFA+P G SL+EA W + + +
Sbjct: 56 HTHLEMPFMGTYSSDDFESGTRAALAGGTTMVVDFALPSPGQSLLEALTMWDNKS-TRAN 114
Query: 127 CDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEAFSRCKEIG 186
CDYS H+A+TWW +QV EM+ +V+DKG+N+FK FMAYK MV D E++ +F RC +G
Sbjct: 115 CDYSFHMAITWWGEQVFNEMETIVKDKGINTFKHFMAYKGALMVDDDEMFSSFQRCAALG 174
Query: 187 AIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAVNCPLYI 246
A+ VHAENGD++A+ K+LA G +GPE H RP VE EA RAI IA CP+YI
Sbjct: 175 ALPLVHAENGDVVAQLQAKLLAEGNSGPEAHAYSRPAEVEGEAANRAIMIADMAGCPVYI 234
Query: 247 VHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMGPPLRPDPS 306
VH + A + I AR G V+GEP+ L D T Y++K+W HAA VM PP R +
Sbjct: 235 VHTSCEQAHEAIRRARAKGMRVFGEPLIQHLTLDETEYFDKDWDHAARRVMSPPFR-NKL 293
Query: 307 TPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIWEKGVHS 366
D L LA+ L TD+C F T QK G DFT+IPNG G+EDRM ++W GV +
Sbjct: 294 HQDSLWAGLASGSLQVVATDHCAFTTEQKRFGVGDFTRIPNGTGGLEDRMPMLWTYGVAT 353
Query: 367 GKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTHHQAVNFN 426
G++ N FVAVTSTN AKI N+YP+KG I VG+DAD+V+WDPK ++TISAKT A+++N
Sbjct: 354 GRITMNEFVAVTSTNIAKILNIYPKKGAILVGADADLVVWDPKRSKTISAKTQQSAIDYN 413
Query: 427 IFEGMVCHGVPLVTISRGKVVYEAGVFSVTAGDGKFIPRKPFAEYIYKRIKQRDRTCTPT 486
+FEG G+P T++RG V E G G G+F+ R PF + + P
Sbjct: 414 VFEGKTVTGLPRFTLTRGVVSIEEGTVKTQEGHGEFVRRDPFPA-VSTALSTWKEVTAPR 472
Query: 487 PVERA 491
V+R+
Sbjct: 473 AVQRS 477
>6AJD-A nrPDB
Length = 485
Score = 650 bits (1676), Expect = 0.0, Method: Composition-based stats.
Identities = 248/484 (51%), Positives = 322/484 (66%), Gaps = 7/484 (1%)
Query: 7 LLIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGIDT 66
LLIRG VV + S ADVL +G+++A+G +L P +G VLD G+ ++PGGID
Sbjct: 3 LLIRGATVVTHEESYRADVLCANGLIQAIGENLETP----SGCDVLDGGGQYLMPGGIDP 58
Query: 67 HTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWADPKVC 126
HTHMQ PFMG+ + +DF GT A L+GGTT IIDF IP SL+EAF TWR WA K
Sbjct: 59 HTHMQLPFMGTVASEDFFSGTAAGLAGGTTSIIDFVIPNPRQSLLEAFHTWRGWA-QKSA 117
Query: 127 CDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEAFSRCKEIG 186
DY HVA+TWWSD+V EM LV GVNSFK FMAYK+ M D L +F RC E+G
Sbjct: 118 ADYGFHVAITWWSDEVAREMGELVAQHGVNSFKHFMAYKNAIMAADDTLVASFERCLELG 177
Query: 187 AIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAVNCPLYI 246
A+ VHAENG+L+ +K+LA G+TGPE H L RP VE EA RAI IA + PLY+
Sbjct: 178 AVPTVHAENGELVFHLQQKLLAQGLTGPEAHPLSRPPQVEGEAASRAIRIAETLGTPLYL 237
Query: 247 VHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMGPPLRPDPS 306
VH+ S+ A IA AR G+ VYGE +A L D + Y + +W AA +VM PP RP
Sbjct: 238 VHISSREALDEIAYARAKGQPVYGEVLAGHLLLDDSVYRHPDWATAAGYVMSPPFRPVE- 296
Query: 307 TPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIWEKGVHS 366
+ L L + +L TT TD+C F QKA+G+DDF+KIPNG G+EDRM+++W+ GV+S
Sbjct: 297 HQEALWRGLQSGNLHTTATDHCCFCAEQKAMGRDDFSKIPNGTAGIEDRMALLWDAGVNS 356
Query: 367 GKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTHHQAVNFN 426
G++ + FVA+TSTN AKIFNL+PRKG I VG+DAD+V+WDP+G+RT+SA THHQ V+FN
Sbjct: 357 GRLSMHEFVALTSTNTAKIFNLFPRKGAIRVGADADLVLWDPQGSRTLSAATHHQRVDFN 416
Query: 427 IFEGMVCHGVPLVTISRGKVVYEAGVFSVTAGDGKFIPRKPFAEYIYKRIKQRDRTCTPT 486
IFEG G+P TIS+GK+++ AG G G+++ R P +Y+ + +R P
Sbjct: 417 IFEGRTVRGIPSHTISQGKLLWAAGDLRAEPGAGRYVER-PAYPSVYEVLGRRAERQRPV 475
Query: 487 PVER 490
VER
Sbjct: 476 AVER 479
>4B91-A nrPDB
Length = 484
Score = 645 bits (1663), Expect = 0.0, Method: Composition-based stats.
Identities = 287/483 (59%), Positives = 367/483 (75%), Gaps = 4/483 (0%)
Query: 2 AAPSRLLIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLP 61
+A R+LI+GG+VVNDD + ADV +E+G+++ +G +L+ PGGA +V+DA GKLV+P
Sbjct: 6 SASVRILIKGGKVVNDDCTHEADVYIENGIIQQVGRELMIPGGA----KVIDATGKLVIP 61
Query: 62 GGIDTHTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWA 121
GGIDT TH FM + +DDF+ GTKAAL GGTTMII +P K SL++A+E R A
Sbjct: 62 GGIDTSTHFHQTFMNATCVDDFYHGTKAALVGGTTMIIGHVLPDKETSLVDAYEKCRGLA 121
Query: 122 DPKVCCDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEAFSR 181
DPKVCCDY+LHV +TWW+ +VK EM+ LV++KGVNSF+MFM YKDLYM+ D ELY+
Sbjct: 122 DPKVCCDYALHVGITWWAPKVKAEMETLVREKGVNSFQMFMTYKDLYMLRDSELYQVLHA 181
Query: 182 CKEIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAVN 241
CK+IGAIA+VHAENG+L+AEGAK+ L LGITGPEG E+ RPE +EAEAT R ITIA+ +
Sbjct: 182 CKDIGAIARVHAENGELVAEGAKEALDLGITGPEGIEISRPEELEAEATHRVITIANRTH 241
Query: 242 CPLYIVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMGPPL 301
CP+Y+V+V S SA VIA A+ GKVV E A G HY++++W HAA +V PPL
Sbjct: 242 CPIYLVNVSSISAGDVIAAAKMQGKVVLAETTTAHATLTGLHYYHQDWSHAAAYVTVPPL 301
Query: 302 RPDPSTPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIWE 361
R D +T +LM+LLAND L +D+ F T QKA+GK+DFTKIP+GV+GV+DRMSVIWE
Sbjct: 302 RLDTNTSTYLMSLLANDTLNIVASDHRPFTTKQKAMGKEDFTKIPHGVSGVQDRMSVIWE 361
Query: 362 KGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTHHQ 421
+GV GKMDENRFVAVTS+NAAK+ NLYPRKGRI G+DAD+V+WDP+ T+TISA T Q
Sbjct: 362 RGVVGGKMDENRFVAVTSSNAAKLLNLYPRKGRIIPGADADVVVWDPEATKTISASTQVQ 421
Query: 422 AVNFNIFEGMVCHGVPLVTISRGKVVYEAGVFSVTAGDGKFIPRKPFAEYIYKRIKQRDR 481
+FN++E M CHGVPLVTISRG+VVYE GVF G GKF P + F + +YK++ QR++
Sbjct: 422 GGDFNLYENMRCHGVPLVTISRGRVVYENGVFMCAEGTGKFCPLRSFPDTVYKKLVQREK 481
Query: 482 TCT 484
T
Sbjct: 482 TLK 484
>1YNY-A nrPDB
Length = 461
Score = 623 bits (1606), Expect = e-179, Method: Composition-based stats.
Identities = 204/463 (44%), Positives = 276/463 (59%), Gaps = 8/463 (1%)
Query: 9 IRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGIDTHT 68
IRGG VV + ADVL+E V A+GH L G +DA G V+PGGID HT
Sbjct: 5 IRGGTVVTAADTYQADVLIEGERVVAIGHQLSVNGA-----EEIDATGCYVIPGGIDPHT 59
Query: 69 HMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWADPKVCCD 128
H+ PF G+ + DDF GT+AA GGTT I+DF + +KG SL A TW A K D
Sbjct: 60 HLDMPFGGTVTADDFFTGTRAAAFGGTTSIVDFCLTKKGESLKSAIATWHEKARGKAVID 119
Query: 129 YSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEAFSRCKEIGAI 188
Y H+ + +DQV EE++ ++ +G+ S K+FMAYK+++ D L++ + KE+GA+
Sbjct: 120 YGFHLMIAEANDQVLEELESVISSEGITSLKVFMAYKNVFQADDETLFKTLVKAKELGAL 179
Query: 189 AQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAVNCPLYIVH 248
QVHAENGD++ KK LA G T P H RP E EAT RAI + + LY+VH
Sbjct: 180 VQVHAENGDVLDYLTKKALAEGNTDPIYHAYTRPPEAEGEATGRAIALTALAGSQLYVVH 239
Query: 249 VMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMGPPLRPDPSTP 308
V SA + IA+AR G VYGE L D ++ A +V PPLR +
Sbjct: 240 VSCASAVQRIAEAREKGWNVYGETCPQYLALD-VSIMDQPDFEGAKYVWSPPLR-EKWNQ 297
Query: 309 DFLMNLLANDDLTTTGTDNCTFN-TCQKALGKDDFTKIPNGVNGVEDRMSVIWEKGVHSG 367
+ L + L N L T G+D+C FN QK LG+ DFTKIPNG +EDR+++++ +GV G
Sbjct: 298 EVLWSALKNGILQTVGSDHCPFNFRGQKELGRGDFTKIPNGGPLIEDRLTILYSEGVRQG 357
Query: 368 KMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTHHQAVNFNI 427
++ N+FV ++ST AAK+F ++PRKG IAVGSDADIVI+DP RT+S +THH V++N
Sbjct: 358 RISLNQFVDISSTKAAKLFGMFPRKGTIAVGSDADIVIFDPHVKRTLSVETHHMNVDYNP 417
Query: 428 FEGMVCHGVPLVTISRGKVVYEAGVFSVTAGDGKFIPRKPFAE 470
FEGM +G + +SRG V F AG G++I R F +
Sbjct: 418 FEGMEVYGEVVSVLSRGSFVVRDKQFVGQAGSGQYIKRTTFEQ 460
>1K1D-A nrPDB
Length = 460
Score = 621 bits (1602), Expect = e-178, Method: Composition-based stats.
Identities = 195/463 (42%), Positives = 270/463 (58%), Gaps = 8/463 (1%)
Query: 8 LIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGIDTH 67
+I+ G +V + A +L++DG + +G +L G V+DA G V PGGID H
Sbjct: 4 IIKNGTIVTATDTYEAHLLIKDGKIAMIGQNLEEKGA-----EVIDAKGCYVFPGGIDPH 58
Query: 68 THMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWADPKVCC 127
TH+ P G+ + DDF GT AA GGTT IIDF + KG L +A ETW + A+ K
Sbjct: 59 THLDMPLGGTVTKDDFESGTIAAAFGGTTTIIDFCLTNKGEPLKKAIETWHNKANGKAVI 118
Query: 128 DYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEAFSRCKEIGA 187
DY H+ ++ +D V EE+ +++++G+ S K+FMAYK+++ D LY KE+GA
Sbjct: 119 DYGFHLMISEITDDVLEELPKVLEEEGITSLKVFMAYKNVFQADDGTLYCTLLAAKELGA 178
Query: 188 IAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAVNCPLYIV 247
+ VHAENGD+I KK LA G T P H L RP +E EAT RA + LY+V
Sbjct: 179 LVMVHAENGDVIDYLTKKALADGNTDPIYHALTRPPELEGEATGRACQLTELAGSQLYVV 238
Query: 248 HVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMGPPLRPDPST 307
HV A + IA+AR G V+GE L D + Y K A +V PPLR +
Sbjct: 239 HVTCAQAVEKIAEARNKGLDVWGETCPQYLVLDQS-YLEKPNFEGAKYVWSPPLR-EKWH 296
Query: 308 PDFLMNLLANDDLTTTGTDNCTFN-TCQKALGKDDFTKIPNGVNGVEDRMSVIWEKGVHS 366
+ L N L N L T G+D C+F+ QK LG+ DFTKIPNG +EDR+S+++ +GV
Sbjct: 297 QEVLWNALKNGQLQTLGSDQCSFDFKGQKELGRGDFTKIPNGGPIIEDRVSILFSEGVKK 356
Query: 367 GKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTHHQAVNFN 426
G++ N+FV + ST AK+F L+P+KG I VGSDAD+VI+DP R ISA+THH AV++N
Sbjct: 357 GRITLNQFVDIVSTRIAKLFGLFPKKGTIVVGSDADLVIFDPNIERVISAETHHMAVDYN 416
Query: 427 IFEGMVCHGVPLVTISRGKVVYEAGVFSVTAGDGKFIPRKPFA 469
FEGM G P+ + RG+ V F G G+++ R +
Sbjct: 417 AFEGMKVTGEPVSVLCRGEFVVRDKQFVGKPGYGQYLKRAKYG 459
>3SFW-A nrPDB
Length = 461
Score = 621 bits (1601), Expect = e-178, Method: Composition-based stats.
Identities = 208/462 (45%), Positives = 275/462 (59%), Gaps = 8/462 (1%)
Query: 9 IRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGIDTHT 68
IR G VV + ADVL++ V A+G DL V+DA G +LPGGID HT
Sbjct: 5 IRNGTVVTASDTYQADVLIDGEKVVAIGSDLQATDA-----EVIDATGYYLLPGGIDPHT 59
Query: 69 HMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWADPKVCCD 128
H+ PF G+ + D+F GTKAA GGTT I+DF + KG SL A TW A K D
Sbjct: 60 HLDMPFGGTVTSDNFFTGTKAAAFGGTTSIVDFCLTSKGESLHSAIATWHEKARGKAVID 119
Query: 129 YSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEAFSRCKEIGAI 188
Y H+ V+ +D V EE++ +V ++G+ S K+FMAYK++ M D L++ R KE+GA+
Sbjct: 120 YGFHLMVSDANDHVLEELESVVNNEGITSLKVFMAYKNVLMADDETLFKTLIRAKELGAL 179
Query: 189 AQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAVNCPLYIVH 248
QVHAENGD++ K+ LA G T P H RP E EAT RAI + + + LY+VH
Sbjct: 180 VQVHAENGDVLDYLTKQALAEGNTDPIYHAYTRPPEAEGEATGRAIALTALADAQLYVVH 239
Query: 249 VMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMGPPLRPDPSTP 308
V A + IA+AR G VYGE L D T K A +V PPLR +
Sbjct: 240 VSCADAVRRIAEAREKGWNVYGETCPQYLVLDITA-LEKPDFEGAKYVWSPPLR-EKWNQ 297
Query: 309 DFLMNLLANDDLTTTGTDNCTFN-TCQKALGKDDFTKIPNGVNGVEDRMSVIWEKGVHSG 367
D L + L N L T G+D+C FN + QK LG+ DFTKIPNG +EDRM++++ +GV G
Sbjct: 298 DVLWSALKNGILQTVGSDHCPFNFSGQKELGRRDFTKIPNGGPIIEDRMTILFSEGVRKG 357
Query: 368 KMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTHHQAVNFNI 427
K+ N+FV +TST AK+F ++P+KG IAVGSDADIV++DP RTIS +THH V++N
Sbjct: 358 KISLNQFVDITSTKVAKLFGMFPQKGTIAVGSDADIVLFDPTVQRTISVETHHMNVDYNP 417
Query: 428 FEGMVCHGVPLVTISRGKVVYEAGVFSVTAGDGKFIPRKPFA 469
FEGM HG + +SRG V F AG G+++ R FA
Sbjct: 418 FEGMQVHGDVISVLSRGAFVVRNKQFVGHAGAGRYVKRSTFA 459
>1GKQ-A nrPDB
Length = 458
Score = 566 bits (1458), Expect = e-161, Method: Composition-based stats.
Identities = 187/461 (40%), Positives = 265/461 (57%), Gaps = 7/461 (1%)
Query: 7 LLIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGIDT 66
LLI+ G ++ D AD+ E + +G +L AP G V+DA GK V PG ID
Sbjct: 2 LLIKNGEIITADSRYKADIYAEGETITRIGQNL----EAPPGTEVIDATGKYVFPGFIDP 57
Query: 67 HTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWADPKVC 126
H H+ PFM + + D G+KAAL GGTT I+ P + +E ++ W+S A+
Sbjct: 58 HVHIYLPFMATFAKDTHETGSKAALMGGTTTYIEMCCPSRNDDALEGYQLWKSKAEGNSY 117
Query: 127 CDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEAFSRCKEIG 186
CDY+ H+AV+ + ++ + +++ +V D G++SFK+F++YK+ + V D E+Y+ KE+G
Sbjct: 118 CDYTFHMAVSKFDEKTEGQLREIVAD-GISSFKIFLSYKNFFGVDDGEMYQTLRLAKELG 176
Query: 187 AIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAVNCPLYI 246
I H EN +L+ +K+L+ G TGPE HE RPEAVEAE T R T Y+
Sbjct: 177 VIVTAHCENAELVGRLQQKLLSEGKTGPEWHEPSRPEAVEAEGTARFATFLETTGATGYV 236
Query: 247 VHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMGPPLRPDPS 306
VH+ K A A+ G +Y E + D T Y + A ++M PPLR D
Sbjct: 237 VHLSCKPALDAAMAAKARGVPIYIESVIPHFLLDKT-YAERGGVEAMKYIMSPPLR-DKR 294
Query: 307 TPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIWEKGVHS 366
L + LA + T GTD+C F+T QK LGK+ FT IPNG+ +EDR+++++ GV
Sbjct: 295 NQKVLWDALAQGFIDTVGTDHCPFDTEQKLLGKEAFTAIPNGIPAIEDRVNLLYTYGVSR 354
Query: 367 GKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTHHQAVNFN 426
G++D +RFV ST AAK+F L+PRKG IAVGSDAD+V++DP+ TIS KT H ++N
Sbjct: 355 GRLDIHRFVDAASTKAAKLFGLFPRKGTIAVGSDADLVVYDPQYRGTISVKTQHVNNDYN 414
Query: 427 IFEGMVCHGVPLVTISRGKVVYEAGVFSVTAGDGKFIPRKP 467
FEG G P V RGKV G F G GK + R+P
Sbjct: 415 GFEGFEIDGRPSVVTVRGKVAVRDGQFVGEKGWGKLLRREP 455
>1NFG-A nrPDB
Length = 457
Score = 530 bits (1364), Expect = e-151, Method: Composition-based stats.
Identities = 173/465 (37%), Positives = 253/465 (54%), Gaps = 11/465 (2%)
Query: 7 LLIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGIDT 66
++I+ G +V D AD+ ++DG + +G L P R +DAAG+ V PGGID
Sbjct: 3 IIIKNGTIVTADGISRADLGIKDGKITQIGGALGP------AERTIDAAGRYVFPGGIDV 56
Query: 67 HTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWADPKVC 126
HTH++ ++S D F T AA GGTT I+DF +G SL EA W A K
Sbjct: 57 HTHVETVSFNTQSADTFATATVAAACGGTTTIVDFCQQDRGHSLAEAVAKWDGMAGGKSA 116
Query: 127 CDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEAFSRCKEIG 186
DY H+ V +D V EE+++L D G+ SFK+FMAY+ + M+ D+ L + + + G
Sbjct: 117 IDYGYHIIVLDPTDSVIEELEVL-PDLGITSFKVFMAYRGMNMIDDVTLLKTLDKAVKTG 175
Query: 187 AIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAVNCPLYI 246
++ VHAENGD K +A G T P H L RP VEAEAT RA+ +A VN P+YI
Sbjct: 176 SLVMVHAENGDAADYLRDKFVAEGKTAPIYHALSRPPRVEAEATARALALAEIVNAPIYI 235
Query: 247 VHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMGPPLRPDPS 306
VHV + + + + A+ G E L + A +V PP R
Sbjct: 236 VHVTCEESLEEVMRAKSRGVRALAETCTHYLYLTK-EDLERPDFEGAKYVFTPPARAKKD 294
Query: 307 TPDFLMNLLANDDLTTTGTDNCT-FNTCQKALGKDDFTKIPNGVNGVEDRMSVIWEKGVH 365
D L N L N T +D+C+ K G++DF IPNG GVE+R+ ++++ GV+
Sbjct: 295 H-DVLWNALRNGVFETVSSDHCSWLFKGHKDRGRNDFRAIPNGAPGVEERLMMVYQ-GVN 352
Query: 366 SGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTHHQAVNF 425
G++ +FV + +T AK+F ++P+KG IAVGSDADIV+WDP+ I H A+++
Sbjct: 353 EGRISLTQFVELVATRPAKVFGMFPQKGTIAVGSDADIVLWDPEAEMVIEQTAMHNAMDY 412
Query: 426 NIFEGMVCHGVPLVTISRGKVVYEAGVFSVTAGDGKFIPRKPFAE 470
+ +EG GVP + RGKV+ + G + DGKF+ R+ + +
Sbjct: 413 SSYEGHKVKGVPKTVLLRGKVIVDEGSYVGEPTDGKFLKRRKYKQ 457
>2FTY-A nrPDB
Length = 559
Score = 481 bits (1237), Expect = e-136, Method: Composition-based stats.
Identities = 150/521 (28%), Positives = 247/521 (47%), Gaps = 68/521 (13%)
Query: 7 LLIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGIDT 66
L+I+ G + A++ V +G V+ + + P G+ V+DA G + PGGID
Sbjct: 5 LIIKNGIICTASDIYAAEIAVNNGKVQLIAASIDPSLGS----EVIDAEGAFITPGGIDA 60
Query: 67 HTHMQFPF-MGSRSIDDFHQGTKAALSGGTTMIIDFA---IPQKGGS-LIEAFET-WRSW 120
H H+ P + +D T++A++GGTT ++ F+ + +KG S L E+ + +
Sbjct: 61 HVHVDEPLKLLGDVVDTMEHATRSAVAGGTTTVVAFSTQDVSKKGPSALAESVKLDVDEY 120
Query: 121 ADPKVCCDYSLHV---AVTWWSDQVKEEMKILVQ----DKGVNSFKMFMAYKDLYMVTDL 173
++ + CDY LH+ + S + +E + + +Q D GV+S KMFM Y L ++D
Sbjct: 121 SEQTLYCDYGLHLILFQIEKPSVEARELLDVQLQAAYNDYGVSSVKMFMTYPGL-QISDY 179
Query: 174 ELYEAFSRCKEIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRA 233
++ A ++ G +HAENGD++ + + G+T H + RP VE EAT RA
Sbjct: 180 DIMSAMYATRKNGFTTMLHAENGDMVKWMIEALEEQGLTDAYYHGVSRPSIVEGEATNRA 239
Query: 234 ITIASAVNCPLYIVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDG------------ 281
IT+A+ ++ P+ VHV S AA+VI A+ G VY E
Sbjct: 240 ITLATTMDTPILFVHVSSPQAAEVIKQAQTKGLKVYAETCPQYALLSDAITRCHHHGEVE 299
Query: 282 -------------THYWNKEW-HHAAHHVMGPPLRPDPSTPDFLMNLLANDDLTTTGTDN 327
+ + N + + ++ PP+RP T + + N T G+D+
Sbjct: 300 SYGVGIDLSSISESPFTNPDDRFIGSKYICSPPIRP-EGTQKSIWKGMNNGTFTIVGSDH 358
Query: 328 CTFNTCQKALGK-------------DDFTKIPNGVNGVEDRMSVIWEKGVHSGKMD-ENR 373
C++N +K +F IPNG+ GV RM ++++ G G + +
Sbjct: 359 CSYNYYEKTSTASKHRAFDPENNKNGEFRYIPNGLPGVCTRMPLLYDYGYLRGNLTSMMK 418
Query: 374 FVAVTSTNAAKIFNLYPRKGRIAVG-SDADIVIWDPKGTRT--------ISAKTHHQAVN 424
V + TN AK++ +YP+KG I G SDAD+VIW P ++ I+ K +
Sbjct: 419 LVEIQCTNPAKVYGMYPQKGSILPGVSDADLVIWYPDDSKKEYNSKPKLITNKLMEHNCD 478
Query: 425 FNIFEGMVCHGVPLVTISRGKVVYEAGVFSVTAGDGKFIPR 465
+ FEG+ P TI +GK+VY+ G DGK++ R
Sbjct: 479 YTPFEGIEIKNWPRYTIVKGKIVYKEGEILKENADGKYLKR 519
>1GKR-A nrPDB
Length = 458
Score = 464 bits (1195), Expect = e-131, Method: Composition-based stats.
Identities = 134/470 (28%), Positives = 220/470 (46%), Gaps = 21/470 (4%)
Query: 7 LLIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGIDT 66
++++ R+V+ D AD+LV+DG V A+ D + R +DA GK V+PG +D
Sbjct: 4 VIVKNCRLVSSDGITEADILVKDGKVAAISADTSDVEAS----RTIDAGGKFVMPGVVDE 59
Query: 67 HTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWADPKVC 126
H H+ + +R F +++A GG T II+ I + ++AF + A ++
Sbjct: 60 HVHIIDMDLKNRY-GRFELDSESAAVGGITTIIEMPITFPPTTTLDAFLEKKKQAGQRLK 118
Query: 127 CDYSLHVA-VTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYM---VTDLELYEAFSRC 182
D++L+ V ++++ + D G FK MA M V+D EL+E F
Sbjct: 119 VDFALYGGGVPGNLPEIRK-----MHDAGAVGFKSMMAASVPGMFDAVSDGELFEIFQEI 173
Query: 183 KEIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAVNC 242
G++ VHAEN +I K++ A G +E +P E EA RA+ + C
Sbjct: 174 AACGSVIVVHAENETIIQALQKQIKAAGGKDMAAYEASQPVFQENEAIQRALLLQKEAGC 233
Query: 243 PLYIVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHV-MGPPL 301
L ++HV + ++I A+ +G+ V+ E L + ++ + PP+
Sbjct: 234 RLIVLHVSNPDGVELIHQAQSEGQDVHCESGPQYLNITTD-----DAERIGPYMKVAPPV 288
Query: 302 RPDPSTPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIWE 361
R L L N + T G+D+ K G D K NG G+E + ++
Sbjct: 289 RSAEMNIR-LWEQLENGLIDTLGSDHGGHPVEDKEPGWKDVWKAGNGALGLETSLPMMLT 347
Query: 362 KGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTHHQ 421
GV+ G++ R V V AK+F +YP+KG + VGSDAD++I D + A
Sbjct: 348 NGVNKGRLSLERLVEVMCEKPAKLFGIYPQKGTLQVGSDADLLILDLDIDTKVDASQFRS 407
Query: 422 AVNFNIFEGMVCHGVPLVTISRGKVVYEAGVFSVTAGDGKFIPRKPFAEY 471
++ F+GM G P++T+ RG VV E G V G G+F+ R+ +
Sbjct: 408 LHKYSPFDGMPVTGAPVLTMVRGTVVAEKGEVLVEQGFGQFVTRRNYEAS 457
>3E74-A nrPDB
Length = 473
Score = 455 bits (1171), Expect = e-128, Method: Composition-based stats.
Identities = 124/466 (26%), Positives = 203/466 (43%), Gaps = 31/466 (6%)
Query: 7 LLIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGIDT 66
L+I+ G V+ ++ + V D+ V+ G + A+G DL V+DA+G +V PG +D
Sbjct: 25 LIIKNGTVILENEARVVDIAVKGGKIAAIGQDLGD------AKEVMDASGLVVSPGMVDA 78
Query: 67 HTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEA-FETWRSWADPKV 125
HTH+ P G + + GT+AA GG T +I+ + Q ++ A E A K+
Sbjct: 79 HTHISEP--GRSHWEGYETGTRAAAKGGITTMIEMPLNQLPATVDRASIELKFDAAKGKL 136
Query: 126 CCDYS-LHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAY-------KDLYMVTDLELYE 177
D + L V++ D++ E + + GV FK F+A D V D + ++
Sbjct: 137 TIDAAQLGGLVSYNIDRLHE-----LDEVGVVGFKCFVATCGDRGIDNDFRDVNDWQFFK 191
Query: 178 AFSRCKEIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIA 237
+ E+G VH EN + E ++ G + RP E EA R + +A
Sbjct: 192 GAQKLGELGQPVLVHCENALICDELGEEAKREGRVTAHDYVASRPVFTEVEAIRRVLYLA 251
Query: 238 SAVNCPLYIVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVM 297
C L++ HV S + + AR++G+ + E D + +E A
Sbjct: 252 KVAGCRLHVCHVSSPEGVEEVTRARQEGQDITCESCPHYFVLDTDQF--EEIGTLAK--C 307
Query: 298 GPPLRPDPSTPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMS 357
PP+R D + L N ++ +D+ C + + K G+ G++ M
Sbjct: 308 SPPIR-DLENQKGMWEKLFNGEIDCLVSDHSP---CPPEMKAGNIMKAWGGIAGLQSCMD 363
Query: 358 VIWEKGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAK 417
V++++ V M F + +TNAA IF L +KGRIA G DAD V P + ++
Sbjct: 364 VMFDEAVQKRGMSLPMFGKLMATNAADIFGLQ-QKGRIAPGKDADFVFIQPNSSYVLTND 422
Query: 418 THHQAVNFNIFEGMVCHGVPLVTISRGKVVYEAGVFSVTAGDGKFI 463
+ + G TI RG V+Y+ A G+FI
Sbjct: 423 DLEYRHKVSPYVGRTIGARITKTILRGDVIYDIEQGFPVAPKGQFI 468
>3HM7-A nrPDB
Length = 448
Score = 438 bits (1127), Expect = e-123, Method: Composition-based stats.
Identities = 119/452 (26%), Positives = 189/452 (41%), Gaps = 24/452 (5%)
Query: 7 LLIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGIDT 66
L+IR VV + + ADV + +G+V A+ +D G + PG +D
Sbjct: 8 LIIRSSTVVTETTTYRADVAIRNGIVSAITEPGSISSDDGPA---IDGTGLHLFPGMVDV 64
Query: 67 HTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLI-EAFETWRSWADPKV 125
H H P G + F G+K+ +GG T D + ++ E + R A+ K
Sbjct: 65 HVHFNEP--GRTEWEGFASGSKSLAAGGVTTYFDMPLNSNPPTITREELDKKRQLANEKS 122
Query: 126 CCDYSLHVAVTWWSDQVKEEMKIL--VQDKGVNSFKMFMA---YKDLYMVTDLELYEAFS 180
DY W V + L + D GV FK FM+ D D L +
Sbjct: 123 LVDYRF------WGGLVPGNIDHLQDLHDGGVIGFKAFMSECGTDDFQFSHDETLLKGMK 176
Query: 181 RCKEIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAV 240
+ +G+I VHAE+ +++ + + + RP E EA R + A
Sbjct: 177 KIAALGSILAVHAESNEMVNALTTIAIEEQRLTVKDYSEARPIVSELEAVERILRFAQLT 236
Query: 241 NCPLYIVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMGPP 300
CP++I HV S+ K I A+ +G V E L + E + A PP
Sbjct: 237 CCPIHICHVSSRKVLKRIKQAKGEGVNVSVETCPHYLLFSLDEFA--EIGYLAK--CAPP 292
Query: 301 LRPDPSTPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIW 360
LR D L + L ++ +D+ + Q GK F ++ G+ G ++ ++V+
Sbjct: 293 LRERQEVED-LWDGLMAGEIDLISSDHSP-SLPQMKTGKTIF-EVWGGIAGCQNTLAVML 349
Query: 361 EKGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTHH 420
+G H KM + V + ST AK F LYP+KG I VG++A + D + T++A +
Sbjct: 350 TEGYHKRKMPLTQIVQLLSTEPAKRFGLYPQKGTIQVGAEASFTLIDLNESYTLNASDLY 409
Query: 421 QAVNFNIFEGMVCHGVPLVTISRGKVVYEAGV 452
+ + G G TI +GK VY+
Sbjct: 410 YRHPISPYVGQRFRGKVKHTICQGKHVYQDHE 441
>3MPG-A nrPDB
Length = 428
Score = 423 bits (1087), Expect = e-118, Method: Composition-based stats.
Identities = 113/456 (24%), Positives = 177/456 (38%), Gaps = 39/456 (8%)
Query: 8 LIRGGRVVNDDFSEVA-DVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGIDT 66
L + GR +N++ VA D+LV+DG + + ++ V+D GKL+ PG +D
Sbjct: 4 LFKNGRYMNEEGKIVATDLLVQDGKIAKVAENITADNA-----EVIDVNGKLIAPGLVDV 58
Query: 67 HTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWADPKVC 126
H H++ P G + GT AA GG T I + E E ++ K
Sbjct: 59 HVHLREP--GGEHKETIETGTLAAAKGGFTTICAMPNTRPVPDCREHMEDLQNRIKEKAH 116
Query: 127 CDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTD-LELYEAFSRCKEI 185
+ + A+T V++ + + + F D V D + A R ++
Sbjct: 117 VNVLPYGAIT-----VRQAGSEMTDFETLKELGAFAFTDDGVGVQDASMMLAAMKRAAKL 171
Query: 186 GAIAQVHAENGDLIAEGA----KKMLALGITGPEGHELCRPEAVEAEATLRAITIASAVN 241
H E LI +G K G+ G P E+ R I +A A +
Sbjct: 172 NMAVVAHCEENTLINKGCVHEGKFSEKHGLNGI-------PSVCESVHIARDILLAEAAD 224
Query: 242 CPLYIVHVMSKSAAKVIADARRDGKVVYGE--PIAASLGTDGTHYWNKEWHHAAHHVMGP 299
C ++ HV +K + +VI DA+R G V E P L D + + M P
Sbjct: 225 CHYHVCHVSTKGSVRVIRDAKRAGIKVTAEVTPHHLVLCEDDIPSADPNFK------MNP 278
Query: 300 PLRPDPSTPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVI 359
PLR + LL + + TD+ +KA G + P G+ G E ++
Sbjct: 279 PLRGKEDHEALIEGLL-DGTIDMIATDHAPHTAEEKAQG---IERAPFGITGFETAFPLL 334
Query: 360 WEKGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTH 419
+ V G + + + + A F L GR+ G ADI I D + I T
Sbjct: 335 YTNLVKKGIITLEQLIQFLTEKPADTFGL--EAGRLKEGRTADITIIDLEQEEEIDPTTF 392
Query: 420 HQAVNFNIFEGMVCHGVPLVTISRGKVVYEAGVFSV 455
F G C G P++TI GK+ ++ V
Sbjct: 393 LSKGKNTPFAGWKCQGWPVMTIVGGKIAWQKESALV 428
>3GRI-A nrPDB
Length = 424
Score = 419 bits (1076), Expect = e-117, Method: Composition-based stats.
Identities = 113/449 (25%), Positives = 182/449 (40%), Gaps = 37/449 (8%)
Query: 8 LIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGIDTH 67
LI+ G+V+ + + AD+L++ V++ + + P G + ++DA G V PG +D H
Sbjct: 3 LIKNGKVLQNGELQQADILIDGKVIKQIAPAIEPSNG----VDIIDAKGHFVSPGFVDVH 58
Query: 68 THMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWADPKVCC 127
H++ P G + GTKAA GG T + + +E FE + D
Sbjct: 59 VHLREP--GGEYKETIETGTKAAARGGFTTVCPMPNTRPVPDSVEHFEALQKLID----- 111
Query: 128 DYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKD-LYMVTDLELYEAFSRCKEIG 186
D + + + S ++ K LV + F D + + T +YE ++
Sbjct: 112 DNAQVRVLPYASITTRQLGKELVDFPALVKEGAFAFTDDGVGVQTASMMYEGMIEAAKVN 171
Query: 187 AIAQVHAENGDLIAEGA----KKMLALGITGPEGHELCRPEAVEAEATLRAITIASAVNC 242
H E+ LI GA K+ LGI G P E+ R + +A A C
Sbjct: 172 KAIVAHCEDNSLIYGGAMHEGKRSKELGIPGI-------PNICESVQIARDVLLAEAAGC 224
Query: 243 PLYIVHVMSKSAAKVIADARRDGKVVYGE--PIAASLGTDGTHYWNKEWHHAAHHVMGPP 300
++ HV +K + +VI DA+R G V E P L D N A + M PP
Sbjct: 225 HYHVCHVSTKESVRVIRDAKRAGIHVTAEVTPHHLLLTEDDIPGNN------AIYKMNPP 278
Query: 301 LRPDPSTPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIW 360
LR L LL + + TD+ +KA K P G+ G E +++
Sbjct: 279 LRSTEDREALLEGLL-DGTIDCIATDHAPHARDEKA---QPMEKAPFGIVGSETAFPLLY 334
Query: 361 EKGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTHH 420
V +G + V + + FNL G + AD+ I D + I +
Sbjct: 335 THFVKNGDWTLQQLVDYLTIKPCETFNL--EYGTLKENGYADLTIIDLDSEQEIKGEDFL 392
Query: 421 QAVNFNIFEGMVCHGVPLVTISRGKVVYE 449
+ F G +G P++T+ G+V +E
Sbjct: 393 SKADNTPFIGYKVYGNPILTMVEGEVKFE 421
>2GWN-A nrPDB
Length = 452
Score = 411 bits (1057), Expect = e-115, Method: Composition-based stats.
Identities = 85/456 (18%), Positives = 167/456 (36%), Gaps = 22/456 (4%)
Query: 2 AAPSRLLIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLP 61
+ ++L+R + N+ + V+++ + + LP + V++ +G + P
Sbjct: 1 SNAMKILLRNALITNEGKTFPGSVMIDGAFISRIIEGELPADDNLSADEVIECSGLRLFP 60
Query: 62 GGIDTHTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWA 121
G ID H + P G ++AA++GG T +D ++ E R
Sbjct: 61 GCIDDQVHFREP--GLTHKATIASESRAAVAGGVTSFMDMPNTNPPTTMWERLLEKRQIG 118
Query: 122 DPKVCCDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDL--ELYEAF 179
+Y T +D + E + V V K+F+ M+ D L + F
Sbjct: 119 ADTAWANYGFFFGGT--NDNIDEIKR--VDKHLVPGLKLFLGSSTGNMLVDNKETLEKIF 174
Query: 180 SRCKEIGAIAQVHAENGDLIAEGAKKMLAL-GIT-GPEGHELCRPEAVEAEATLRAITIA 237
C + H E ++I + A G H L R E ++ A+ +A
Sbjct: 175 GECDLL---IATHCEKEEIIRANKEHYKAKYGNDLDIHFHPLIRSEEACYRSSAEAVELA 231
Query: 238 SAVNCPLYIVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVM 297
+N L+I+H+ ++ + R+ + I + + + + ++ + +
Sbjct: 232 ERMNARLHILHLSTEKELSLF----RNDIPTAQKRITSEVCVHHLWFSDTDYGRLGNRIK 287
Query: 298 GPPLRPDPSTPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMS 357
P S + L + N + TD+ +K + +G V+ +
Sbjct: 288 WNPAIKKESDREALRAAVRNGRIDIIATDHAPHLLREKE---GSCLQAASGGPLVQHSLL 344
Query: 358 VIWEKGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAK 417
+ + + G V+ T+ A +F + ++G I G AD+V+ DP T+SA
Sbjct: 345 ALL-ELCNQGIFSIEEIVSKTAHIPATLFAI-EKRGYIRPGYYADLVLVDPSSPHTVSAD 402
Query: 418 THHQAVNFNIFEGMVCHGVPLVTISRGKVVYEAGVF 453
++ FEG T G + Y G
Sbjct: 403 NILSLCGWSPFEGFTFSHSVAYTFVNGCLAYAKGRL 438
>1XRT-A nrPDB
Length = 467
Score = 369 bits (947), Expect = e-102, Method: Composition-based stats.
Identities = 94/457 (20%), Positives = 173/457 (37%), Gaps = 49/457 (10%)
Query: 6 RLLIRGGRVVN--DDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGG 63
+L+++ G V++ + D+LVE+G ++ + ++L P ++DA G +V PG
Sbjct: 48 KLIVKNGYVIDPSQNLEGEFDILVENGKIKKIDKNILVPEA-----EIIDAKGLIVCPGF 102
Query: 64 IDTHTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWADP 123
ID H H++ P G +D G++ A++GG T I+ D
Sbjct: 103 IDIHVHLRDP--GQTYKEDIESGSRCAVAGGFTTIVCMPNTNPP-------------IDN 147
Query: 124 KVCCDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLE--------- 174
+Y L + + +V I KG F + K+ V +
Sbjct: 148 TTVVNYILQKSKSVGLCRVLPTGTITKGRKG-KEIADFYSLKEAGCVAFTDDGSPVMDSS 206
Query: 175 -LYEAFSRCKEIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRA 233
+ +A ++G H E+ L ++ G R E R
Sbjct: 207 VMRKALELASQLGVPIMDHCEDDKLAYG----VINEGEVSALLGLSSRAPEAEEIQIARD 262
Query: 234 ITIASAVNCPLYIVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAA 293
+A ++I HV +K + ++I + G + E L N A
Sbjct: 263 GILAQRTGGHVHIQHVSTKLSLEIIEFFKEKGVKITCEVNPNHLLFTEREVLN----SGA 318
Query: 294 HHVMGPPLRPDPSTPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVE 353
+ + PPLR + + + TD+ T +K L + +P G+ G++
Sbjct: 319 NARVNPPLRKKEDRLALIEG-VKRGIIDCFATDHAPHQTFEKELVE---FAMP-GIIGLQ 373
Query: 354 DRMSVIWEKGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRT 413
+ + G + + + + + N A+I + G + +GS ADI I+DP
Sbjct: 374 TALPSAL-ELYRKGIISLKKLIEMFTINPARIIGV--DLGTLKLGSPADITIFDPNKEWI 430
Query: 414 ISAKTHHQAVNFNIFEGMVCHGVPLVTISRGKVVYEA 450
++ +T+ G V G + TI GK+VY+
Sbjct: 431 LNEETNLSKSRNTPLWGKVLKGKVIYTIKDGKMVYKD 467
>2Z00-A nrPDB
Length = 426
Score = 349 bits (895), Expect = 2e-96, Method: Composition-based stats.
Identities = 104/466 (22%), Positives = 176/466 (37%), Gaps = 65/466 (13%)
Query: 7 LLIRGGRVVNDDFSE-VADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGID 65
+LIR R+V+ ADVL+ +G + +L +V+D G + PG +D
Sbjct: 2 ILIRNVRLVDARGERGPADVLIGEGRILSLEGGE--------AKQVVDGTGCFLAPGFLD 53
Query: 66 THTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWADPKV 125
H H++ P G +D G AA+ GG T ++ + EA + A K
Sbjct: 54 LHAHLREP--GEEVKEDLFSGLLAAVRGGYTDLVSMPNTKPPVDTPEAVRALKEKA--KA 109
Query: 126 CCDYSLHVAVTWWSDQ----------VKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLEL 175
LH A Q ++E +L+ D G + + L M
Sbjct: 110 LGLARLHPAAALTEKQEGKTLTPAGLLREAGAVLLTDDGRTNEDAGVLAAGLLMAAP--- 166
Query: 176 YEAFSRCKEIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRP-EAVEAEA----- 229
+G VHAE+ L G GP L P EAEA
Sbjct: 167 ---------LGLPVAVHAEDAGLRRNGVM------NDGPLADLLGLPGNPPEAEAARIAR 211
Query: 230 ---TLRAITIASAVNCPLYIVHVMSKSAAKVIADARRDGKVVYGE--PIAASLGTDGTHY 284
LR S L++ H+ +K +++ +A+R G V E P +L +
Sbjct: 212 DLEVLRYALRRSPATPRLHVQHLSTKRGLELVREAKRAGLPVTAEATPHHLTLTEEALRT 271
Query: 285 WNKEWHHAAHHVMGPPLRPDPSTPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTK 344
++ + + PPLR + L LL + L TD+ +K D +
Sbjct: 272 FDPLFK------VAPPLRGEEDREALLEGLL-DGTLDAIATDHAPHTLAEKE---KDLLR 321
Query: 345 IPNGVNGVEDRMSVIWEKGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIV 404
P G+ +E +++ + R V + + ++ L P + G++A +V
Sbjct: 322 APFGIPSLEVAFPLLYTELHLKRGFPLQRLVELFTDGPRRVLGLPPL--HLEEGAEASLV 379
Query: 405 IWDPKGTRTISAKTHHQAVNFNIFEGMVCHGVPLVTISRGKVVYEA 450
+ PK R + ++ + G V G P++T+ G++V+EA
Sbjct: 380 LLSPK-ERPVDPSAFASKARYSPWAGWVLGGWPVLTLVAGRIVHEA 424
>6HG1-A nrPDB
Length = 371
Score = 226 bits (576), Expect = 2e-59, Method: Composition-based stats.
Identities = 78/408 (19%), Positives = 134/408 (32%), Gaps = 56/408 (13%)
Query: 60 LPGGIDTHTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRS 119
LPG ID H H++ P G +DF GT AAL+GG TM+ + A +
Sbjct: 6 LPGLIDVHVHLREP--GGTHKEDFASGTAAALAGGITMVCAMPNTRPPIIDAPALALAQK 63
Query: 120 WADPKVCCDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEAF 179
A+ CD++L + + S+ + G+ + + VT + +
Sbjct: 64 LAEAGARCDFALFLGAS--SENAGTLGTVAGSAAGLKLYLANATTNSSHGVTSVVQWMEH 121
Query: 180 SRCKEIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASA 239
HAE + A + +A
Sbjct: 122 FETWPSHLPIVAHAEEQTVAA--------------------------------VLMVAQL 149
Query: 240 VNCPLYIVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMGP 299
++I HV K +I A+ G V E L + E + P
Sbjct: 150 TQRSVHICHVARKEEILLIKAAKARGLPVTCEVAPHHLFLSHD---DLERLGPGKGEVRP 206
Query: 300 PLRPDPSTPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVI 359
L N+ + +D+ +K ++ P G G+E + ++
Sbjct: 207 ELGSRQDVEALWENM---AVIDCFASDHAPHTLEEKCG-----SRPPPGFPGLETMLPLL 258
Query: 360 WEKGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTH 419
V G++ + + N +IF+L P++ V D + TI +
Sbjct: 259 LT-AVSEGRLSLDDLLQRLHHNPRRIFHLPPQEDT--------YVEVDLEHEWTIPSHMP 309
Query: 420 HQAVNFNIFEGMVCHGVPLVTISRGKVVYEAGVFSVTAGDGKFIPRKP 467
++ FEG G + RG+V Y G V G G+ + + P
Sbjct: 310 FSKAHWTPFEGQKVKGTVRRVVLRGEVAYIDGQVLVPPGYGQDVRKWP 357
>3OOQ-A nrPDB
Length = 396
Score = 102 bits (254), Expect = 4e-22, Method: Composition-based stats.
Identities = 83/440 (18%), Positives = 133/440 (30%), Gaps = 108/440 (24%)
Query: 1 MAAPSRLLIRGGRVVN-DDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLV 59
M+ ++L + V DVLV +G V +G ++ P ++D GK +
Sbjct: 1 MSLSVKILFKNATVFPITSRPFKGDVLVSNGKVEKVGENIEDPDA-----EIVDLTGKFL 55
Query: 60 LPGGIDTHTHM-----------------QFPFMGSRSIDDFHQ----GTKAALSGGTTMI 98
PG +D H+H+ P D + AL+GG T +
Sbjct: 56 FPGFVDAHSHIGLFEEGVGYYYSDGNEATDPVTPHVKALDGFNPQDPAIERALAGGVTSV 115
Query: 99 IDFAIPQKGGSLIEAFETWRSWADPKVCCD--YSLHVAVTWWSDQVKEEMKIL----VQD 152
+ + +RS + L +A +V E K +
Sbjct: 116 MIVPGSANPVGGQGSVIKFRSIIVEECIVKDPAGLKMAFGENPKRVYGERKQTPSTRMGT 175
Query: 153 KGV-----NSFKMFMAYKDLYMVTDLELYEAFSRCKEIGAIAQVHAENGDLIAEGAKKML 207
GV K +M K+L E E + E G+++ KK+
Sbjct: 176 AGVIRDYFTKVKNYMKKKELAQKEGKEFTETDLKM-----------EVGEMV--LRKKIP 222
Query: 208 ALGITGPEGHELCRPEAVEAEATLRAITIASAVNCPLYIVHVMSKSAAKVIADARRDGKV 267
A H A+ L AI IA L I H + ++
Sbjct: 223 AR----MHAH--------RADDILTAIRIAEEFGFNLVIEH-----GTEAYKISK----- 260
Query: 268 VYGEPIAASLGTDGTHYWNKEWHHAAHHVMGPPLRPDPSTPDFLMNLLANDDLTTTGTDN 327
V E + + K L T + + LL + L D+
Sbjct: 261 VLAEKKIPVVVGPLLTFRTK-------------LELKDLTMETIAKLLKDGVLIALMCDH 307
Query: 328 CTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIWEKGVHSGKMDENRFVAVTSTNAAKIFN 387
IP V+ ++ + E + + + N AKI
Sbjct: 308 ---------------PVIPLEFATVQAATAMRY-------GAKEEDLLKILTVNPAKILG 345
Query: 388 LYPRKGRIAVGSDADIVIWD 407
L R G I G DAD+V+W
Sbjct: 346 LEDRIGSIEPGKDADLVVWS 365
>2VUN-A nrPDB
Length = 386
Score = 89.8 bits (221), Expect = 3e-18, Method: Composition-based stats.
Identities = 42/163 (25%), Positives = 68/163 (41%), Gaps = 17/163 (10%)
Query: 5 SRLLIRG-GRVVNDDFSEV----ADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLV 59
S+ +I+ G++V+ D ++VEDG++ A+G + L A ++DAAG V
Sbjct: 2 SKTIIKNIGKIVSGDIKSPVLQADTIVVEDGLIAAIGGEELMKDAGDA--TIIDAAGSTV 59
Query: 60 LPGGIDTHTHMQ-FPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQ-KGGSLIEAFETW 117
PG +DTH H+ + + DF +AL GG T +I P G A
Sbjct: 60 TPGLLDTHVHVSGGDYAPRQKTMDF---ISSALHGGVTTMISAGSPHFPGRPKDAAGTKA 116
Query: 118 RSWADPKVCCDYSL-----HVAVTWWSDQVKEEMKILVQDKGV 155
+ K + H + EE I ++ +GV
Sbjct: 117 LAITLSKSYYNARPAGVKVHGGAVILEKGLTEEDFIEMKKEGV 159
>3GIQ-A nrPDB
Length = 480
Score = 87.1 bits (214), Expect = 2e-17, Method: Composition-based stats.
Identities = 82/449 (18%), Positives = 144/449 (32%), Gaps = 71/449 (15%)
Query: 9 IRGGRVVNDDF--SEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGIDT 66
I GG +++ AD+ V DG + A+G GA DA+GK+V PG ID
Sbjct: 11 ITGGWIIDGTGAPRRRADLGVRDGRIAAIGE-----LGAHPARHAWDASGKIVAPGFIDV 65
Query: 67 HTH-----MQFPFMGSRSIDDFHQ------GTKAA---LSGGTTMII----DFAIPQKGG 108
H H ++ P + ++ G AA L G T + + +
Sbjct: 66 HGHDDLMFVEKPDLRWKTSQGITTVVVGNCGVSAAPAPLPGNTAAALALLGETPLFADVP 125
Query: 109 SLIEAFETWRSWADPKVCCDYS---------LHVAVTWWSDQVKEEMKILVQDKGVNSFK 159
+ A + R + ++ A T Q ++M + G F
Sbjct: 126 AYFAALDAQRPMINVAALVGHANLRLAAMRDPQAAPTAAEQQAMQDMLQAALEAGAVGFS 185
Query: 160 MFMAYKDLYMVTDLELYEAFSRCKEIGAIAQVHAENG-DLIAEGAKKMLALGI-----TG 213
+AY+ + EL E + H N D + +++LA+G T
Sbjct: 186 TGLAYQPGAVAQAAELEGLARVAAERRRLHTSHIRNEADGVEAAVEEVLAIGRGTGCATV 245
Query: 214 PEGHELCRP-EAVEAEATLRAITIASAVNCPLYIVHVMSKSAAKVIADARRDGKV----V 268
H+ P + ATL I A + + ++ ++ R +
Sbjct: 246 VSHHKCMMPQNWGRSRATLANIDRAREQGVEVALDIYPYPGSSTILIPERAETIDDIRIT 305
Query: 269 YGEPIA---ASLGTDGTHYWNKEWHHAAHHVMGP----PLRPDPSTPDFLMNLLANDDLT 321
+ P D W + AA + P D +
Sbjct: 306 WSTPHPECSGEYLADIAARWGCDKTTAARRL-APAGAIYFAMDEDEVKRIFQHPCC---- 360
Query: 322 TTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIWEKGVHSGKMDENRFVAVTSTN 381
G+D + FT+ V+ + M + VA +
Sbjct: 361 MVGSDGLPNDARPHPRLWGSFTR-------------VLGRYVREARLMTLEQAVARMTAL 407
Query: 382 AAKIFNLYPRKGRIAVGSDADIVIWDPKG 410
A++F + +G + G+ AD+V++DP
Sbjct: 408 PARVFG-FAERGVLQPGAWADVVVFDPDT 435
>2PUZ-A nrPDB
Length = 419
Score = 84.4 bits (207), Expect = 1e-16, Method: Composition-based stats.
Identities = 70/432 (16%), Positives = 125/432 (28%), Gaps = 76/432 (17%)
Query: 23 ADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGIDTHTHMQFPFMGSRSIDD 82
A + V +G + G + P D G+ + P ID HTH+ G +
Sbjct: 40 AVIAVRNGRIAFAGPESDLPDDLSTADETTDCGGRWITPALIDCHTHL---VFGGNRAME 96
Query: 83 FHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWADPKVCCDYSLHVAVTWWSDQV 142
F A + I + GG ++ + R+ +D + Q
Sbjct: 97 FEMRLNGA------TYEE--IAKAGGGIVSSVRDTRALSDEVLVA-------------QA 135
Query: 143 KEEMKILVQDKGVNSFKMFMAY-----KDLYMVTDLELYEAFSRCKEIGAIAQVHAENGD 197
+ L+ + GV++ ++ Y +L M+ E + + + HA D
Sbjct: 136 LPRLDTLLSE-GVSTIEIKSGYGLDIETELKMLRVARRLETLRPVRIVTSYLAAHATPAD 194
Query: 198 LIAEGAKKMLALGITGPE-GHELCRPE----AVEAEA-----TLRAITIASAVNCP--LY 245
A + + + G E H + E A R A P L+
Sbjct: 195 YKGRNADYITDVVLPGLEKAHAEGLADAVDGFCEGIAFSVKEIDRVFAAAQQRGLPVKLH 254
Query: 246 IVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMGPPLRPDP 305
+ + A++ A +L D Y ++ A
Sbjct: 255 AEQLSNLGGAELAAS-------------YNALSADHLEYLDETGAKALA----------- 290
Query: 306 STPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIWE--KG 363
+ +L + G + + G S++ G
Sbjct: 291 --KAGTVAVLLPGAFYALREKQLPPVQALRDAGA-EIALATDCNPGTSPLTSLLLTMNMG 347
Query: 364 VHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTHHQAV 423
+M + T+ NAAK L G + G AD IWD + + +
Sbjct: 348 ATLFRMTVEECLTATTRNAAKALGLLAETGTLEAGKSADFAIWDIERPAEL-----VYRI 402
Query: 424 NFNIFEGMVCHG 435
FN + G
Sbjct: 403 GFNPLHARIFKG 414
>1FWC-C nrPDB
Length = 567
Score = 78.6 bits (192), Expect = 7e-15, Method: Composition-based stats.
Identities = 77/432 (17%), Positives = 125/432 (28%), Gaps = 82/432 (18%)
Query: 2 AAPSRLLIRGGRVVNDDFSEVADVLVEDGVVRALG--------HDLLPPGGAPAGLRVLD 53
A L++ +V+ AD+ V+DG + A+G ++ P GA V+
Sbjct: 63 ADCVDLVLTNALIVDHWGIVKADIGVKDGRIFAIGKAGNPDIQPNVTIPIGA--ATEVIA 120
Query: 54 AAGKLVLPGGIDTHTHMQFPFMGSRSIDDFHQGTKAALSGGTTMII---------DFAIP 104
A GK+V GGIDTH H P AL G T ++ A
Sbjct: 121 AEGKIVTAGGIDTHIHWICPQQAEE-----------ALVSGVTTMVGGGTGPAAGTHATT 169
Query: 105 -QKGGSLIEAFETWRSWADPKVCCDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMA 163
G I A + + L E GV K+
Sbjct: 170 CTPGPWYISRMLQ----AADSLPVNIGLLGKGNVSQPDALREQVA----AGVIGLKI--- 218
Query: 164 YKDLYMVTDLELYEAFSRCKEIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPE 223
+ + T + A + E+ +H+ + G
Sbjct: 219 -HEDWGATPAAIDCALTVADEMDIQVALHS------DTLNESGFVEDTLAAIGGRTIHTF 271
Query: 224 AVEAEATLRAITIASAVNCPLYIVHVMSKSAAKVIADARRDGKVVYGEPIAASL-GTDGT 282
E A I I+ + I L
Sbjct: 272 HTEGAGGGHAPDII-TACAHPNILPSSTNPTL-----------PYTLNTIDEHLDMLMVA 319
Query: 283 HYWNKEWHHAAHHVMGPPLRPDPSTPDFLMNLLANDDLTTTGTDNCTFNTCQKALGK--D 340
H+ + + R + D L +L + T +D +A+G+ +
Sbjct: 320 HHLDPDIAEDVAFAESRIRRETIAAEDVLHDL---GAFSLTSSD-------SQAMGRVGE 369
Query: 341 DFTKIPNGVNGVEDRMSV----IWEKGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIA 396
+ V RM V + E+ + R++A + N A + G I
Sbjct: 370 VILRTWQ----VAHRMKVQRGALAEETGDNDNFRVKRYIAKYTINPALTHGIAHEVGSIE 425
Query: 397 VGSDADIVIWDP 408
VG AD+V+W P
Sbjct: 426 VGKLADLVVWSP 437
>1RK6-A nrPDB
Length = 496
Score = 75.5 bits (184), Expect = 5e-14, Method: Composition-based stats.
Identities = 98/520 (18%), Positives = 159/520 (30%), Gaps = 100/520 (19%)
Query: 2 AAPSRLLIRGGRVVNDDFS--EVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLV 59
A P ++ GG V++ + +ADV V + A+G A + R +D AGK+V
Sbjct: 18 ATPFDYILSGGTVIDGTNAPGRLADVGVRGDRIAAVGD-----LSASSARRRIDVAGKVV 72
Query: 60 LPGGIDTHTHMQFPFMGSR-SIDDFHQGTKAALSG--GTTMI-IDFAIPQKGGSLIEA-- 113
PG ID+HTH + R QG ++G G ++ + A P L++
Sbjct: 73 SPGFIDSHTHDDNYLLKHRDMTPKISQGVTTVVTGNCGISLAPLAHANPPAPLDLLDEGG 132
Query: 114 ---------FETWRSWADP--KVCCDYSLHVAVTWWSDQVKEE--------MKILVQDK- 153
+ A P C ++ E M+ L D
Sbjct: 133 SFRFARFSDYLEALRAAPPAVNAACMVGHSTLRAAVMPDLRREATADEIQAMQALADDAL 192
Query: 154 --GVNSFKMFMAYKDLYMVTDLELYEAFSRCKEIGAIAQVHAENGDLIAEGAKKMLALGI 211
G Y + E+ E G + H + EG + AL
Sbjct: 193 ASGAIGISTGAFYPPAAHASTEEIIEVCRPLITHGGVYATH-----MRDEGEHIVQALEE 247
Query: 212 TGPEGHELCRPEAV---------------EAEATLRAITIASAVNCPLY-IVHVMSKSAA 255
T G EL P + E A + A + V+ Y V +
Sbjct: 248 TFRIGRELDVPVVISHHKVMGKLNFGRSKETLALIEAAMASQDVSLDAYPYVAGSTMLKQ 307
Query: 256 KVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMGPPLRP---------DPS 306
+ A R + + +P G D + + + + P L+P +P
Sbjct: 308 DRVLLAGRT-LITWCKPYPELSGRDLEEIAAERGK--SKYDVVPELQPAGAIYFMMDEPD 364
Query: 307 TPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIWEKGVHS 366
+LA T G+D + F + V+
Sbjct: 365 VQ----RILAFGP-TMIGSDGLPHDERPHPRLWGTFPR-------------VLGHYSRDL 406
Query: 367 GKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTHHQAVNFN 426
G V + A F L R G++ G AD+V++DP +
Sbjct: 407 GLFPLETAVWKMTGLTAAKFGLAER-GQVQPGYYADLVVFDPATV-----------ADSA 454
Query: 427 IFEGMVCHGVPLV-TISRGKVVYEAGVFSVTAGDGKFIPR 465
FE + G V+E F+ G+ + R
Sbjct: 455 TFEHPTERAAGIHSVYVNGAAVWEDQSFTGQH-AGRVLNR 493
>3QGK-C nrPDB
Length = 568
Score = 75.1 bits (183), Expect = 6e-14, Method: Composition-based stats.
Identities = 75/512 (14%), Positives = 147/512 (28%), Gaps = 96/512 (18%)
Query: 7 LLIRGGRVVNDDFSEVADVLVEDGVVRALGH--------DLLPPGGAPAGLRVLDAAGKL 58
L+I +++ AD+ +++G + +G + P G L G +
Sbjct: 67 LVITNALIIDYTGIYKADIGIKNGKIHGIGKAGNKDMQDGVTPHMVVGVGTEALAGEGMI 126
Query: 59 VLPGGIDTHTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIID---FAIPQKGGSLIEAFE 115
+ GGID+HTH P AL+ G T + + + I
Sbjct: 127 ITAGGIDSHTHFLSPQQFPT-----------ALANGVTTMFGGGTGPVDGTNATTITP-G 174
Query: 116 TWRSWADPKVCCDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLEL 175
W + +Y ++V + + + G FK+ + + T +
Sbjct: 175 VWNLHRMLRAAEEYGMNVGLLGKGNSSSRAQLVEQVKAGAIGFKL----HEDWGTTPSAI 230
Query: 176 YEAFSRCKEIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAIT 235
S E +H + + + A+ + + E + IT
Sbjct: 231 DHCLSVADEYDVQVCIHTDTVNEAGYVDDTLRAMNGRAIHAYHI---EGAGGGHSPDVIT 287
Query: 236 IASAVNCPLYIVHVMSKSAAKVIADARRDGKVVYGEPIAASL-GTDGTHYWNKEWHHAAH 294
+A VN I+ + +A L H+ +K
Sbjct: 288 MAGEVN----ILPSSTTPT-----------IPYTINTVAEHLDMLMTCHHLDKRIREDLQ 332
Query: 295 HVMGPPLRPDPSTPDFLMNLLANDDLTTTGTDNCTFNTCQKALGK--DDFTKIPNGVNGV 352
R P + L + T +D +A+G+ + + +
Sbjct: 333 FSQS---RIRPGSIAAEDTLHDMGVIAMTSSD-------SQAMGRAGEVIPRTWQTADKN 382
Query: 353 EDRMSVIWEKGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTR 412
+ + E+ + R+++ + N A + G + G AD+V+W+P
Sbjct: 383 KKEFGRLTEEKGDNDNFRIKRYISKYTINPAITHGVSEYIGSVEEGKIADLVVWNP---- 438
Query: 413 TISAKTHHQAVNFNIFEGMVCHGVPLVTISRGKVVYEA----------------GVFSVT 456
F G+ P + I G VV+
Sbjct: 439 --------------AFFGVK----PKIIIKGGMVVFSEMGDSNASVPTPQPVYYREMFGH 480
Query: 457 AGDGKFIPRKPFAEYIYKRIKQRDRTCTPTPV 488
G KF F + +++ V
Sbjct: 481 HGKAKFDTSITFVSKVAYENGIKEKLGLERKV 512
>2VHL-A nrPDB
Length = 396
Score = 74.0 bits (180), Expect = 2e-13, Method: Composition-based stats.
Identities = 79/454 (17%), Positives = 143/454 (31%), Gaps = 72/454 (15%)
Query: 1 MAAPSRLLIRGGRVVNDDFSEV-ADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLV 59
MA LLI+ +V ++ V + DG + + + P + A ++
Sbjct: 1 MAES--LLIKDIAIVTENEVIKNGYVGINDGKISTVSTE---RPKEPYSKEIQAPADSVL 55
Query: 60 LPGGIDTHTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRS 119
LPG ID H H G D S T I+ +P++G + A +
Sbjct: 56 LPGMIDIHIH------GGYGADTMD------ASFSTLDIMSSRLPEEGTTSFLATTITQE 103
Query: 120 WAD-PKVCCDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEA 178
+ + + A S E + I ++ V+ + K+ +D+EL++
Sbjct: 104 HGNISQALVNAREWKAAEESSLLGAELLGIHLEGPFVSPKRAGAQPKEWIRPSDVELFKK 163
Query: 179 F-SRCKEIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIA 237
+ + I + A D E + + I GH +A ++ A
Sbjct: 164 WQQEAGGLIKIVTL-APEEDQHFELIRHLKDESIIASMGH---------TDADSALLSDA 213
Query: 238 SAVNCPLYIVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVM 297
+ ++ H+ + + + G + + L DG H + A
Sbjct: 214 AKAGAS-HMTHLYNAMSPFHHREPGVIGTALAHDGFVTELIADGIH-SHPLAAKLAFLAK 271
Query: 298 GPP---LRPDPSTPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVED 354
G L D L + + + T L K+ G + +
Sbjct: 272 GSSKLILITDSMRAKGLKDGVYEFGGQSVTVRGRTALLSDGTL-AGSILKMNEGARHMRE 330
Query: 355 RMSVIWEKGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTI 414
+ +TS NAAK ++ RKG + VG DAD+VI
Sbjct: 331 -----FTNC------SWTDIANITSENAAKQLGIFDRKGSVTVGKDADLVIVSSDCE--- 376
Query: 415 SAKTHHQAVNFNIFEGMVCHGVPLVTISRGKVVY 448
++TI RG + +
Sbjct: 377 ----------------------VILTICRGNIAF 388
>4CEX-C nrPDB
Length = 570
Score = 73.6 bits (179), Expect = 2e-13, Method: Composition-based stats.
Identities = 68/416 (16%), Positives = 123/416 (29%), Gaps = 56/416 (13%)
Query: 7 LLIRGGRVVNDDFSEVADVLVEDGVVRALGHD--------LLPPGGAPAGLRVLDAAGKL 58
LL+ +++ AD+ V+DG + +G + P V+ A GK+
Sbjct: 69 LLLTNALILDYTGIYKADIGVKDGYIVGIGKGGNPDIMDGVTPNMIVGTATEVIAAEGKI 128
Query: 59 VLPGGIDTHTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAI----PQKGGSLIEAF 114
V GGIDTH H P AL+ G T + K ++
Sbjct: 129 VTAGGIDTHVHFINPDQ-----------VDVALANGITTLFGGGTGPAEGSKATTVTPGP 177
Query: 115 ETWRSWADPKVCCDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLE 174
++ + + M+ + D G K+ + + T
Sbjct: 178 WNIEKMLKSTEGLPINVGILGKGHGSSIAPIMEQI--DAGAAGLKI----HEDWGATPAS 231
Query: 175 LYEAFSRCKEIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAI 234
+ + + E +H++ + + A I G H VE A
Sbjct: 232 IDRSLTVADEADVQVAIHSDTLNEAGFLEDTLRA--INGRVIHSF----HVEGAGGGHAP 285
Query: 235 TIASAVNCPLYIVHVMSKSAAKVIADARRDGKVVYGEPIAASL-GTDGTHYWNKEWHHAA 293
I + P V+ + + I L H+ +
Sbjct: 286 DIMAMAGHP------------NVLPSSTNPTRPFTVNTIDEHLDMLMVCHHLKQNIPEDV 333
Query: 294 HHVMGPPLRPDPSTPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVE 353
R P T L ++ TD + + + ++
Sbjct: 334 AFADS---RIRPETIAAEDILHDLGIISMMSTD-----ALAMGRAGEMVLRTWQTADKMK 385
Query: 354 DRMSVIWEKGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPK 409
+ + E+ S R+V+ + N A + G I G AD+V+W+PK
Sbjct: 386 KQRGPLAEEKNGSDNFRLKRYVSKYTINPAIAQGIAHEVGSIEEGKFADLVLWEPK 441
>2ICS-A nrPDB
Length = 379
Score = 69.0 bits (167), Expect = 5e-12, Method: Composition-based stats.
Identities = 72/455 (15%), Positives = 136/455 (29%), Gaps = 86/455 (18%)
Query: 1 MAAPSRLLIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAA-GKLV 59
M+ LLI+ G+ VN ++ +++ + A+ + + + + G V
Sbjct: 1 MSLDYDLLIKNGQTVNG---MPVEIAIKEKKIAAVAATI-----SGSAKETIHLEPGTYV 52
Query: 60 LPGGIDTHTH-MQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWR 118
G ID H H + + D+ + G T +ID G + E +
Sbjct: 53 SAGWIDDHVHCFEKMALYYDYPDEI------GVKKGVTTVIDA-----GTTGAENIHEFY 101
Query: 119 SWADPKVCCDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEA 178
A + L V ++ W ++E+ L + + K D + +
Sbjct: 102 DLAQQAKTNVFGL-VNISKWGIVAQDELADLSKVQASLVKKAIQELPDFVVGIKARMSRT 160
Query: 179 FSRCKEIGAIAQVHAENGDLIAEGAKKMLALGITGPE-GHELCRPEAVEAEATLRAITIA 237
+ G E AK++ P H P + +
Sbjct: 161 V--IGDNGITPL----------ELAKQIQQENQEIPLMVHIGSAPP-----HLDEILALM 203
Query: 238 SAVNCPLYIVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVM 297
+ + H + ++ A K + + D H + H A
Sbjct: 204 EKGDV---LTHCFNGKENGILDQATDKIKDFAWQAYNKGVVFDIGHGTDSFNFHVA---- 256
Query: 298 GPPLRPDPSTPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMS 357
L + + TD I N NG ++
Sbjct: 257 ----------ETALREGMKAASI---STD----------------IYIRNRENGPVYDLA 287
Query: 358 VIWEKGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKG-TRTISA 416
EK G D + + A+ F+L +KG + +G DAD+ I+ + +T++
Sbjct: 288 TTMEKLRVVG-YDWPEIIEKVTKAPAENFHL-TQKGTLEIGKDADLTIFTIQAEEKTLTD 345
Query: 417 KTHHQAVNFNIFEGMVCHGVPLVTISRGKVVYEAG 451
V P+ TI G++ G
Sbjct: 346 SNGLTRVA-------KEQIRPIKTIIGGQIYDNEG 373
>4WGX-A nrPDB
Length = 465
Score = 68.2 bits (165), Expect = 9e-12, Method: Composition-based stats.
Identities = 84/470 (17%), Positives = 147/470 (31%), Gaps = 54/470 (11%)
Query: 7 LLIRGGRVVNDDFSEVA---DVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGG 63
+ I GG +++ + V +EDG + +G +R +DA GK +LPG
Sbjct: 5 IAIVGGTLIDGNGGVPVPETTVFIEDGRITKVGS--TDQIEVHPNIRQIDAQGKWILPGL 62
Query: 64 IDTHTHMQF--PFMGS-----------RSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSL 110
++ + H+ MG + + AL GG T + D + ++
Sbjct: 63 VNGNVHLLDGIMMMGRGGIEYLARFEGNYYKVIEEAAQIALRGGVTTVFDTWNALEPVTI 122
Query: 111 IEAFETWRSWADPKVCCDYS---------LHVAVTWWSDQVKEEMKILVQDKGVNSFKMF 161
A + S A ++ S Q + M D+ F++
Sbjct: 123 --ARDRIASGAAEGARIFFAGTLIGMGGPFTGDFMRPSMQARTVMSRTFADRMDAMFEVG 180
Query: 162 MAYKDLYMVTDLELYEAFSRCKEIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCR 221
M + L + E+ E G A L+ G P R
Sbjct: 181 MG-RHLSTLPPAEVRPLIREYLERGVDFCKIAVTDHLVGLL-------GFRAPYFTFSER 232
Query: 222 PEAVEAEATLRAITIASAVNCPLYIVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDG 281
V + RA L ++ + A ++ A G+ E L
Sbjct: 233 VLDVLVDEVRRAGVPLLTHTTSLEGLNTAIERDADLMIHATMTGQAPIPEETIEKLLEKQ 292
Query: 282 THYWNKEWHHAAHHVMGP---P---LRPDPSTPDFLMNLLANDDLTTTGTDN-CTFNTCQ 334
+ A M P + + ++ GTD CT
Sbjct: 293 LWSEVQPTTIAQQAWMDSVDHPFADFSGRVHHENDVR-MIKAGVPLVLGTDAGCTDPDIL 351
Query: 335 KALGKDDFTKIPNGVNGVEDRMSVIWEKGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGR 394
+ + + + + P + ED +W + + MD + + N AK + + G
Sbjct: 352 EDMSQGELHERPWTLG--EDHF--VWMQAMVEKGMDPMAAILAGTANPAKAYRKFDELGS 407
Query: 395 IAVGSDADIVIWDPKGTRTISAKTHHQAVNFNIFEGMV--CHGVPLVTIS 442
I VG D+V+ D I+ V + EG HG+PL +
Sbjct: 408 IDVGKLGDVVVLDQDPLADITNMRTLSHV---VKEGREIDFHGLPLSPLV 454
>1E9Y-B nrPDB
Length = 569
Score = 65.5 bits (158), Expect = 5e-11, Method: Composition-based stats.
Identities = 67/414 (16%), Positives = 120/414 (28%), Gaps = 54/414 (13%)
Query: 7 LLIRGGRVVNDDFSEVADVLVEDGVV--------RALGHDLLPPGGAPAGLRVLDAAGKL 58
L+I +V+ AD+ ++DG + + + + L G +
Sbjct: 68 LIITNALIVDYTGIYKADIGIKDGKIAGIGKGGNKDMQDGVKNNLSVGPATEALAGEGLI 127
Query: 59 VLPGGIDTHTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWR 118
V GGIDTH H P + F G + GG T D W
Sbjct: 128 VTAGGIDTHIHFISPQQIPTA---FASGVTTMIGGG-TGPADGTNATTITPGRRNL-KWM 182
Query: 119 SWADPKVCCDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEA 178
A + + + + + + + G FK+ + + T + A
Sbjct: 183 LRAAEEYSMNLGF---LAKGNASNDASLADQI-EAGAIGFKI----HEDWGTTPSAINHA 234
Query: 179 FSRCKEIGAIAQVHAE--NGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITI 236
+ +H + N E +A G T H E A I
Sbjct: 235 LDVADKYDVQVAIHTDTLNEAGCVEDTMAAIA-GRTMHTFH-------TEGAGGGHAPDI 286
Query: 237 ASAVNCPLYIVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHV 296
I+ + V E + H+ +K
Sbjct: 287 IKVAGEH-NILPASTNPTIP---------FTVNTEAEHMDMLMVC-HHKDKSIKEDVQFA 335
Query: 297 MGPPLRPDPSTPDFLMNLLANDDLTTTGTDNCTFNTCQKALGK--DDFTKIPNGVNGVED 354
R P T L + T +D +A+G+ + T+ + +
Sbjct: 336 DS---RIRPQTIAAEDTLHDMGAFSITSSD-------SQAMGRVGEVITRTWQTADKNKK 385
Query: 355 RMSVIWEKGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDP 408
+ E+ + R+++ + N A + G + VG AD+V+W P
Sbjct: 386 EFGRLKEEKGDNDNFRIKRYLSKYTINPAIAHGISEYVGSVEVGKVADLVLWSP 439
>4CQD-A nrPDB
Length = 423
Score = 64.7 bits (156), Expect = 9e-11, Method: Composition-based stats.
Identities = 81/470 (17%), Positives = 147/470 (31%), Gaps = 82/470 (17%)
Query: 1 MAAPSRLLIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVL 60
M+ L+IR + D D+ + + + + +DA G LV
Sbjct: 21 MSKDFDLIIRNAYLSEKDSVY--DIGIVGDRIIKIEAKI-----EGTVKDEIDAKGNLVS 73
Query: 61 PGGIDTHTHMQFPFMGS-RSIDDFHQG--TK-AALSGGTTMIIDFAIPQKGGSLIE--AF 114
PG +D HTHM F + + F T+ AA+ G + + +IE
Sbjct: 74 PGFVDAHTHMDKSFTSTGERLPKFWSRPYTRDAAIEDGLKYYKNATHEEIKRHVIEHAHM 133
Query: 115 ETWRSWADPKVCCDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVT--- 171
+ + D VA T + V E + L + ++ + + V
Sbjct: 134 QVLHGTLYTRTHVDVD-SVAKTKAVEAVLEAKEELKD---LIDIQVVAFAQSGFFVDLES 189
Query: 172 DLELYEAFSR-CKEIGAIAQVHAENG-----DLIAEGAKKMLALGITGPEGHELCRPEAV 225
+ + ++ C +G + EN DL + AK+ H++ V
Sbjct: 190 ESLIRKSLDMGCDLVGGVDPATRENNVEGSLDLCFKLAKEYDVD--IDYHIHDIG---TV 244
Query: 226 EAEATLRAITIASAVNCPLYIVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYW 285
+ R +A Y V + SAA ADA + E I Y
Sbjct: 245 GVYSINR---LAQKTIENGYKGRVTT-SAAWCFADAPSEWLD---EAIPL--------YK 289
Query: 286 NKEWHHAAHHVMGPPLRPDPSTPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKI 345
+ PP P ++ LL +DN DF +
Sbjct: 290 DSGMKFVTCFSSTPPTMP-------VIKLLEAGINLGCASDN-----------IRDFW-V 330
Query: 346 PNGVNGVEDRMSVIWEKGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVI 405
P G + + ++ D + ++ A++ + G I VG AD+V+
Sbjct: 331 PFGNGDMVQGALIETQRLELKTNRDLGLIWKMITSEGARVLGIEKNYG-IEVGKKADLVV 389
Query: 406 WDPKGTRTISAKTHHQAVNFNIFEGMVCHGVPLVTISRGKVVYEAGVFSV 455
+ + + ++ L I G+++ + V
Sbjct: 390 LN----------------SLSPQWAIIDQAKRLCVIKNGRIIVKDEVIVA 423
>2AQV-A nrPDB
Length = 390
Score = 63.9 bits (154), Expect = 1e-10, Method: Composition-based stats.
Identities = 72/413 (17%), Positives = 133/413 (32%), Gaps = 60/413 (14%)
Query: 2 AAPSRLLIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLP 61
A L++G + + + DVLV +G + A+ ++ P V+D +G+++ P
Sbjct: 5 TAAGFTLLQGAHLYAPEDRGICDVLVANGKIIAVASNI--PSDIVPNCTVVDLSGQILCP 62
Query: 62 GGIDTHTHMQFPFM-GSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSW 120
G ID H H+ + G T ++ E+
Sbjct: 63 GFIDQHVHLIGGGGEAGPTTRTPEVALSRLTEAGVTSVVGLLGTDSISRHPESLLAKTRA 122
Query: 121 ADPKVCCDYSLHVAVTWWSDQVKE--EMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEA 178
+ + + L A S + E + + D+ V K A D ++Y
Sbjct: 123 LNEEGISAWMLTGAFHVPSRTITGSVEKDVAIIDR-VIGVKC--AISDHRSAAP-DVYHL 178
Query: 179 FSRCKEIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIAS 238
+ E + + G + AL P L + +
Sbjct: 179 ANMAAESRVGGLLGGKPGVTVFHMGDSKKALQ---PIYDLL----ENCDVPISKLLPTHV 231
Query: 239 AVNCPLYIVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMG 298
N PL+ + A + AR+ G D T ++
Sbjct: 232 NRNVPLF------EQALE---FARKGG------------TIDITSSIDE----------- 259
Query: 299 PPLRPDPSTPDFLMNL--LANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRM 356
P+ P + LA L++ G + F + + T I GV G E +
Sbjct: 260 -PVAPAEGIARAVQAGIPLARVTLSSDGNGSQPFFDDE-----GNLTHI--GVAGFETLL 311
Query: 357 SVIWEKGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPK 409
+ + V + + +++ A NL KG I G+DAD+++ P+
Sbjct: 312 ETV-QVLVKDYDFSISDALRPLTSSVAGFLNLTG-KGEILPGNDADLLVMTPE 362
>2OGJ-A nrPDB
Length = 417
Score = 63.6 bits (153), Expect = 2e-10, Method: Composition-based stats.
Identities = 68/395 (17%), Positives = 121/395 (30%), Gaps = 87/395 (22%)
Query: 24 DVLVE-DGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGIDTHTHMQFPFMGSRSIDD 82
D+L+ DG + A+G L P +DA G + PG +D H H+ + G D
Sbjct: 37 DILIGGDGKIAAVGSALQAPADTQR----IDAKGAFISPGWVDLHVHI---WHGGT--DI 87
Query: 83 FHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWADPKVCCDYSLHVAVTWWSDQV 142
+ ++ G T ++D + + H + +
Sbjct: 88 SIRPSECGAERGVTTLVDAG----------------------SAGEANFHGFREYIIEPS 125
Query: 143 KEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEAFSRCKEIGAIAQVHAENGDLIAEG 202
+E +K + + G +L + D++L +AEN + I
Sbjct: 126 RERIKAFL-NLGSIGLVACNRVPELRDIKDIDLDRILEC----------YAENSEHIVGL 174
Query: 203 AKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAVNCPLYIVHVMSKSAA-KVIADA 261
+ H + V + IA + P+ +VHV A + +
Sbjct: 175 KVRA---------SHVITGSWGVTPVKLGK--KIAKILKVPM-MVHVGEPPALYDEVLEI 222
Query: 262 RRDGKVVYGEPIAASLGTDGTH-YWNKEWHHAAHHVMGPPLRPDPSTP------DFLMNL 314
G VV G G+ +++ + A G +R D
Sbjct: 223 LGPGDVVT----HCFNGKSGSSIMEDEDLFNLAERCAGEGIRLDIGHGGASFSFKVAEAA 278
Query: 315 LANDDLT-TTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIWEKGVHSGKMDENR 373
+A L + TD + + V + MS + M
Sbjct: 279 IARGLLPFSISTDLHGHS-------------MNFPVWDLATTMSKLLSV-----DMPFEN 320
Query: 374 FVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDP 408
V + N A + L R+ VG AD ++D
Sbjct: 321 VVEAVTRNPASVIRLDMEN-RLDVGQRADFTVFDL 354
>3MKV-A nrPDB
Length = 426
Score = 63.6 bits (153), Expect = 2e-10, Method: Composition-based stats.
Identities = 72/449 (16%), Positives = 140/449 (31%), Gaps = 104/449 (23%)
Query: 8 LIRGGRVVNDD---FSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGI 64
L R G +++ D + ++L+EDG +R + + V+D GK ++PG I
Sbjct: 7 LFRNGALLDPDHPDLLQGFEILIEDGFIREVSD----KPIKSSNAHVIDVKGKTIMPGLI 62
Query: 65 DTHTH-----MQFPFMGSR----SIDDFHQGTKAALSGGTTMIID-----FAIPQKGGSL 110
D H H P + + +A L G T + D + Q S
Sbjct: 63 DLHVHVVAIEFNLPRVATLPNVLVTLRAVPIMRAMLRRGFTTVRDAGGAGYPFKQAVESG 122
Query: 111 I----------EAFETWRSWADPKVCCDY-------------SLHVAVTWWSDQVKEEMK 147
+ A ADP+ DY V D+V+ ++
Sbjct: 123 LVEGPRLFVSGRALSQTGGHADPRARSDYMPPDSPCGCCVRVGALGRVADGVDEVRRAVR 182
Query: 148 ILVQDKGVNSFKMFMAYKDLYMVTDLELYEAFSRCKEIGAIAQVHAENGDLIAEGAKKML 207
+Q G + K+ MA + TD V + D I +
Sbjct: 183 EELQ-MGADQIKI-MASGGVASPTD---------------PVGVFGYSEDEIRAIVAEAQ 225
Query: 208 ALGITGPEGHELCRPEAVEAEATLRAITIASAVNCPLYIVHVMSKSAAKVIADARRDGKV 267
G T H P A RA+ V + +I D
Sbjct: 226 GRG-TYVLAHAYT-PA-----AIARAVR-----------CGVRTIEHGNLIDDETARLVA 267
Query: 268 VYGEPIAASLGTDGTHYWNKEWHHAAHHVMGPPLRPDPSTPDFLMNLLANDDLTTTGTDN 327
+G + +L T ++ + + P + + +
Sbjct: 268 EHGAYVVPTLVT-----YDALASEGEKYGLPP------------------ESIAKIADVH 304
Query: 328 CTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIWEKG-VHSGKMDENRFVAVTSTNAAKIF 386
+ K K+ G + + + + ++ + + + +A + +A++
Sbjct: 305 GA-GLHSIEIMKRAGVKMGFGTDLLGEAQRLQSDEFRILAEVLSPAEVIASATIVSAEVL 363
Query: 387 NLYPRKGRIAVGSDADIVIWDPKGTRTIS 415
+ + GRI G+ AD+++ D +++
Sbjct: 364 GMQDKLGRIVPGAHADVLVVDGNPLKSVD 392
>3IV8-A nrPDB
Length = 381
Score = 62.0 bits (149), Expect = 6e-10, Method: Composition-based stats.
Identities = 70/406 (17%), Positives = 137/406 (33%), Gaps = 59/406 (14%)
Query: 11 GGRVVNDDFSEVAD-VLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGIDTHTH 69
++ + V V++ + A+ P P+ + V+D G + PG ID +
Sbjct: 9 NCKIYTGNDVLVKHAVIINGDKIEAV----CPIESLPSEMNVVDLNGANLSPGFIDLQLN 64
Query: 70 MQF--PFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWADPKVCC 127
F + + KA L G T + I ++ +A R +
Sbjct: 65 GCGGVMFNDEITAETIDTMHKANLKSGCTSFLPTLITSSDENMRQAIAAAREYQAKYPNQ 124
Query: 128 DYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEAFSRCKEIGA 187
LH+ + + V KG++S D +D + + ++ A
Sbjct: 125 SLGLHLEGPYLN----------VMKKGIHSV-------DFIRPSDDTMIDTICANSDVIA 167
Query: 188 IAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRA-ITIASAVNCPLYI 246
+ EN E +K++ GI GH EA + + IT A+ ++
Sbjct: 168 KVTLAPENNK--PEHIEKLVKAGIVVSIGH--TNATYSEARKSFESGITFAT------HL 217
Query: 247 VHVMSKSAAKVIADARRDGKV--VYGEP-IAASLGTDGTHYWNKEWHHAAHHVMGPPLRP 303
+ M+ R G V +Y P + A + DG H A+ + ++
Sbjct: 218 FNAMTP------MVGREPGVVGAIYDTPEVYAGIIADGFH------VDYANIRIAHKIKG 265
Query: 304 DPSTPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVI--WE 361
+ A ++ +K +D NG G +++I +
Sbjct: 266 EKLVLVTDATAPAGAEMDYF------IFVGKKVYYRDGKCVDENGTLG-GSALTMIEAVQ 318
Query: 362 KGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWD 407
V + + + + + AK + + GRI G A++ ++D
Sbjct: 319 NTVEHVGIALDEALRMATLYPAKAIGVDEKLGRIKKGMIANLTVFD 364
>3HPA-A nrPDB
Length = 479
Score = 60.9 bits (146), Expect = 1e-09, Method: Composition-based stats.
Identities = 92/480 (19%), Positives = 153/480 (31%), Gaps = 78/480 (16%)
Query: 2 AAPSRLLIRGGRV-VNDDFSEV----ADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAG 56
+ P LL++ V V D + A + +ED + A+G P VLD G
Sbjct: 26 SRPKTLLVKHADVLVTMDDTRRELRDAGLYIEDNRIVAVGPSAELPE---TADEVLDLRG 82
Query: 57 KLVLPGGIDTHTHMQFPFMGSRSIDDFHQGTKAALSGGTTM---IIDFAIPQK-GGSLIE 112
LV+PG ++TH HM + A L G T I P+ S +
Sbjct: 83 HLVIPGLVNTHHHMYQSLTRAVPA-----AQNAELFGWLTNLYKIWAHLTPEMIEVSTLT 137
Query: 113 AFETWRSWADPKVCCDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTD 172
A ++ + D + +I ++ M + +D + D
Sbjct: 138 AMAELLQSGCTTSSDHLYIYPNGSRLDDSIGAAQRIGMRFHASRG-AMSVGQRDGGLPPD 196
Query: 173 LELYEAFSRCKEIGAIAQV-HAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATL 231
+ ++ + + H EG ML + + C P +V +
Sbjct: 197 SVVEREPDILRDTQRLIETYH-------DEGRYAMLRVVV------APCSPFSVSRDLMR 243
Query: 232 RAITIASAVNCPLYIVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHH 291
A +A L+ H+ IA +R +G A D + WH
Sbjct: 244 DAAVLAREYGVSLH-THL--AENVNDIAYSREK----FGMT-PAEYAEDLGWVGHDVWHA 295
Query: 292 AAHHVMGPPLRPDPSTPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKI------ 345
+ D + L A T TG +C + + A G K+
Sbjct: 296 HCVQL-----------DDAGIGLFAR---TGTGVAHCPCSNMRLASGIAPVKKMRLAGVP 341
Query: 346 -PNGVNGV----------EDRMSVIWEK-GVHSGKMDENRFVAVTSTNAAKIFNLYPRKG 393
GV+G E R +++ ++ G M + + + AK+ N G
Sbjct: 342 VGLGVDGSASNDGAQMVAEVRQALLLQRVGFGPDAMTAREALEIATLGGAKVLN-RDDIG 400
Query: 394 RIAVGSDADIVIWDPKGTRTISAKTHHQAVNFNIFEGMVCHGVPLVTISRGKVVYEAGVF 453
+ G AD +D + + A H V +F T+ GKVV G
Sbjct: 401 ALKPGMAADFAAFDLRQP--LFAGALHDPVAALVFCA---PSQTAYTVVNGKVVVREGRL 455
>2PLM-A nrPDB
Length = 406
Score = 60.9 bits (146), Expect = 1e-09, Method: Composition-based stats.
Identities = 76/473 (16%), Positives = 147/473 (31%), Gaps = 115/473 (24%)
Query: 7 LLIRGGRVVND--DFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGI 64
++I ++ D V +E+G ++ + + LD +GKLV+P
Sbjct: 1 MIIGNCLILKDFSSEPFWGAVEIENGTIKRVLQGEVKVD--------LDLSGKLVMPALF 52
Query: 65 DTHTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWADPK 124
+THTH + + D +FE W
Sbjct: 53 NTHTHAPMTLLRGVAED------------------------------LSFEEW------- 75
Query: 125 VCCDYSLHVAVTWWSDQVKEEM--------KILVQDKGVNSFKMFMAYKD--LYMVTDLE 174
L V D++ E+M ++ + G+ F +++ V D
Sbjct: 76 ------LFSKVLPIEDRLTEKMAYYGTILAQMEMARHGIAGFVDMYFHEEWIAKAVRDFG 129
Query: 175 LYEAFSRCKEIGAIAQVHAENGDLIAEGAKKMLA----LGITGPEGHELCRPEAVEAEAT 230
+ +R + + ++G + E K G P E
Sbjct: 130 MRALLTR-----GLVDSNGDDGGRLEENLKLYNEWNGFEGRIFVGFGPHS-PYLCSEEYL 183
Query: 231 LRAITIASAVNCPLYIVHV--MSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKE 288
R A ++N P+ I H+ SK + + + G ++ H +
Sbjct: 184 KRVFDTAKSLNAPVTI-HLYETSKEEYDL------EDILNIGLKEVKTIAAHCVHLPERY 236
Query: 289 WHHAAH---HVMGPPLRPDPSTPDF--LMNLLANDDLTTTGTDNCTFNTCQKALGKDDFT 343
+ V P + ++ + T GTD N
Sbjct: 237 FGVLKDIPFFVSHNPASNLKLGNGIAPVQRMIEHGMKVTLGTDGAASN------------ 284
Query: 344 KIPNGVNGV-EDRMSVIWEKGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDAD 402
N +N E R++ + +K + +D N + + + + A+ + G+I G +AD
Sbjct: 285 ---NSLNLFFEMRLASLLQKAQNPRNLDVNTCLKMVTYDGAQAMGF--KSGKIEEGWNAD 339
Query: 403 IVIWDPKGTR--TISAKTHHQAVNFNIFEGMVCHGVPLVTISRGKVVYEAGVF 453
+V+ D + +H F+ G T+ GK +Y G +
Sbjct: 340 LVVIDLDLPEMFPVQNIKNHLVHAFS--------GEVFATMVAGKWIYFDGEY 384
>3DUG-A nrPDB
Length = 408
Score = 60.9 bits (146), Expect = 1e-09, Method: Composition-based stats.
Identities = 70/462 (15%), Positives = 132/462 (28%), Gaps = 92/462 (19%)
Query: 10 RGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGIDTHTH 69
+G + AD+L+ +G + +G V+ +++PG +D+H H
Sbjct: 13 KGYLDIQTGEIIKADLLIRNGKIAEIGK------INTKDATVISIPDLILIPGLMDSHVH 66
Query: 70 MQFPFMGSRS--IDDFHQGT-------KAALSGGTTMIIDFAIPQ-KGGSLIEAFETWRS 119
+ D H GT + L G T + + S+ +A E R
Sbjct: 67 IVGNDSKGEESIADSSHMGTVWGVVNAEKTLMAGFTTVRNVGAANYADVSVRDAIE--RG 124
Query: 120 WADPKVCCDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEAF 179
+ + +T L+ + F + + + E +
Sbjct: 125 VINGPTMLVSGPALGITGGHCD-----HNLLPPE-------FNYSSEGVVDSPWEARKMV 172
Query: 180 SRCKEIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASA 239
+ ++ GA G +++ + L +A+ EA + +A+
Sbjct: 173 RKNRKYGADLIKFCATGGVMSRNTD-------VNAKQFTLEEMKAIVDEAHNHGMKVAAH 225
Query: 240 VNCPLYIVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHY-WNKEWHHAAHHVMG 298
+ + I K+ + A I + + + A
Sbjct: 226 AHGLIGI-KAAIKAGVDSVEHASFIDDETIDMAIKNNTVLSMDIFVSDYILGEGAKAG-- 282
Query: 299 PPLRPDPSTPDFL---------MNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGV 349
+R + + L MN + T GTD F+ +G
Sbjct: 283 --IREESLNKERLVGKKQRENFMNAHRRGAIITFGTDAGIFD---------------HGD 325
Query: 350 NGVEDRMSVIWEKGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPK 409
N + V W M + ++ A +F + G+I G DADIV
Sbjct: 326 NAKQFAYMVEW-------GMTPLEAIQASTIKTATLFGI-ENIGQIKEGFDADIV----- 372
Query: 410 GTRTISAKTHHQAVNFNIFEGMVCHGVPLVTISRGKVVYEAG 451
I N + + GKV G
Sbjct: 373 --GVIE----------NPLANIRTLEEVAFVMKEGKVYKREG 402
>4Z42-C nrPDB
Length = 572
Score = 60.1 bits (144), Expect = 2e-09, Method: Composition-based stats.
Identities = 83/505 (16%), Positives = 149/505 (29%), Gaps = 82/505 (16%)
Query: 7 LLIRGGRVVNDD-FSEVADVLVEDGVVRALGH--DLLPPGGAPAGLRV------LDAAGK 57
L+I +V+ ADV + DG + +G + G GL V +
Sbjct: 70 LVITNVTIVDARLGVIKADVGIRDGKIAGIGKSGNPGVMDGVTPGLVVGVSTDAISGEHL 129
Query: 58 LVLPGGIDTHTHMQFPFMGSRSIDDFHQGTKAALSGGT--TMIIDFAIPQKGGSLIEAFE 115
++ GIDTH H+ P ++ G GG T + G +
Sbjct: 130 ILTAAGIDTHIHLISP---QQAYHALSNGVATFFGGGIGPTDGTNGTTVTPGP--WNIRQ 184
Query: 116 TWRSWADPKVCCDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLEL 175
RS V L ++ + E+ GV +K+ + + T L
Sbjct: 185 MLRSVEGLPVNVG-ILGKGNSYGRGPLLEQ-----AIAGVVGYKV----HEDWGATANAL 234
Query: 176 YEAFSRCKEIGAIAQVHAENGDLIAEGAKKMLA-LGITGPEGHELCRPEAVEAEATLRAI 234
+ E+ VH ++ + + A G T H E I
Sbjct: 235 RHSLRMADEMDIQVSVHTDSLNECGYVEDTIDAFEGRTIHTFHT----EGAGGGHAPDII 290
Query: 235 TIASAVNCPLYIVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAH 294
+AS N ++ + G E + + A
Sbjct: 291 RVASQPN----VLPSSTNPTLPY-------GVNSQAELFDMIMVCHNLNPNVPADVSFAE 339
Query: 295 HVMGPPLRPDPSTPDFLMNLLANDDLTTTGTDNCTFNTCQKALGK--DDFTKIPNGVNGV 352
R P T L ++ +D +A+G+ +++ ++ N +
Sbjct: 340 S------RVRPETIAAENVLHDMGVISMFSSD-------SQAMGRVGENWLRVMQTANAM 386
Query: 353 EDRMSVIWEKGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTR 412
+ + E + R+VA + N A + G + VG AD+V+WDP
Sbjct: 387 KASRGKLPEDAPGNDNFRVLRYVAKITINPAIAQGVSHVIGSVEVGKMADLVLWDP---- 442
Query: 413 TISAKTHHQAVNFNIFEGMVCHGVPLVTISRGKVVYEAGVFSVTAGDGKFIPRKPFAEYI 472
P + I G + + A P+ F +
Sbjct: 443 ------------------RFFGAKPKMVIKGGMINWAA---MGDPNASLPTPQPVFYRPM 481
Query: 473 YKRIKQRDRTCTPTPVERAPYKGEV 497
+ + + + T V +A V
Sbjct: 482 FGAMGKTMQDTCVTFVSQAALDDGV 506
>4V1Y-A nrPDB
Length = 494
Score = 58.6 bits (140), Expect = 6e-09, Method: Composition-based stats.
Identities = 40/123 (32%), Positives = 50/123 (40%), Gaps = 34/123 (27%)
Query: 7 LLIRGGRVVNDDFSEV--AD--VLVEDGVVRALG-HDLLPPGGAPAGLRVLDAAGKLVLP 61
L I+ G +V D D V V+DG + ALG H P P RV+DA GK+VLP
Sbjct: 24 LSIQHGTLVTMDQYRRVLGDSWVHVQDGRIVALGVHAESVP---PPADRVIDARGKVVLP 80
Query: 62 GGIDTHTHMQF------PFMGSRSIDDFHQ----GTKA----------------ALSGGT 95
G I+ HTH+ P G + D G KA A+ G
Sbjct: 81 GFINAHTHVNQILLRGGPSHGRQFYDWLFNVVYPGQKAMRPEDVAVAVRLYCAEAVRSGI 140
Query: 96 TMI 98
T I
Sbjct: 141 TTI 143
Score = 42.8 bits (99), Expect = 4e-04, Method: Composition-based stats.
Identities = 16/90 (17%), Positives = 32/90 (35%), Gaps = 5/90 (5%)
Query: 369 MDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTHHQAVNFNIF 428
+ + + + + + A+ + G I G AD+++ D + +T HH +F
Sbjct: 378 LTPEKILEMATIDGARSLGMDHEIGSIETGKRADLILLDLRHPQT---TPHHHLAATIVF 434
Query: 429 EGMVCHGVPLVTISRGKVVYEAGVFSVTAG 458
+ + G VV E S
Sbjct: 435 QAY--GNEVDTVLIDGNVVMENRRLSFLPP 462
>3T8L-A nrPDB
Length = 608
Score = 57.4 bits (137), Expect = 1e-08, Method: Composition-based stats.
Identities = 20/67 (29%), Positives = 33/67 (49%), Gaps = 6/67 (8%)
Query: 7 LLIRGGRVVN--DDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGI 64
+LI GG +V+ AD+ + ++ ++ P +V+DA G V PG I
Sbjct: 37 VLITGGTLVDVVTGELRPADIGIVGALIASVHE----PASRRDAAQVIDAGGAYVSPGLI 92
Query: 65 DTHTHMQ 71
DTH H++
Sbjct: 93 DTHMHIE 99
>2BB0-A nrPDB
Length = 421
Score = 56.6 bits (135), Expect = 3e-08, Method: Composition-based stats.
Identities = 64/394 (16%), Positives = 115/394 (29%), Gaps = 41/394 (10%)
Query: 23 ADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGIDTHTHMQFPFMGSRSIDD 82
A V + + + G ++D +G+LV PG +D HTH+ F GSR +
Sbjct: 38 AVVGIHEQKIVFAGQK--GAEAGYEADEIIDCSGRLVTPGLVDPHTHL--VFGGSREKE- 92
Query: 83 FHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWADPKVCCDYSLHVAVTWWSDQV 142
L G +D I +GG ++ + R+ ++ ++ H+
Sbjct: 93 ----MNLKLQG--ISYLD--ILAQGGGILSTVKDTRAASEEELLQKAHFHLQRMLSYGTT 144
Query: 143 KEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEAFSRCKEIGAIAQVHAENGDLIAEG 202
E+K + K K L+ ++L F I + + D + +
Sbjct: 145 TAEVKSGYGLEKETELKQLRVAKKLHESQPVDLVSTFMGAHAI--PPEYQNDPDDFLDQM 202
Query: 203 AKKM--LALGITGPEGHELCRPEAVEAEATLRAITIASAVNCPLYIVHVMSKSAAKVIAD 260
+ + + R + A+ L I H +
Sbjct: 203 LSLLPEIKEQELASFADIFTETGVFTVSQSRRYLQKAAEAGFGLKI-H---ADEIDPLGG 258
Query: 261 ARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMGPPLRPDPSTPDFLMNLLANDDL 320
A GK+ +D E A + G ST ++
Sbjct: 259 AELAGKLKAVSADHLVGTSDEGIKKLAEAGTIAVLLPGTTFYLGKSTYARARAMIDEGVC 318
Query: 321 TTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIWEKGVHSGKMDENRFVAVTST 380
+ TD ++ + + +I KM +
Sbjct: 319 VSLATDFNPGSSPT-------------------ENIQLIMSIAALHLKMTAEEIWHAVTV 359
Query: 381 NAAKIFNLYPRKGRIAVGSDADIVIWD-PKGTRT 413
NAA G++ G AD+VIW P
Sbjct: 360 NAAYAIGKGEEAGQLKAGRSADLVIWQAPNYMYI 393
>5T5I-A nrPDB
Length = 569
Score = 56.2 bits (134), Expect = 3e-08, Method: Composition-based stats.
Identities = 21/66 (31%), Positives = 35/66 (53%), Gaps = 12/66 (18%)
Query: 8 LIRGGRV---VNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGI 64
+I+ G V +N E D+ V+DG + +V+DA+GK+V+PGG+
Sbjct: 4 IIKNGFVYCPLNGVDGEKMDICVKDGKIVE---------SVSDSAKVIDASGKIVMPGGV 54
Query: 65 DTHTHM 70
D H+H+
Sbjct: 55 DPHSHI 60
Score = 53.5 bits (127), Expect = 2e-07, Method: Composition-based stats.
Identities = 19/95 (20%), Positives = 37/95 (38%), Gaps = 9/95 (9%)
Query: 367 GKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTHHQAVNFN 426
+ + +T +AK+ L KG + VG+DADI ++D T+ + A+
Sbjct: 431 REYTFSEIAQITRATSAKVLGLSDTKGHLGVGADADIAVYDIN-PETVDPSAEYMAIE-- 487
Query: 427 IFEGMVCHGVPLVTISRGKVVYEAGVFSVTAGDGK 461
+ G++V + G + G+
Sbjct: 488 -----EAFSRAACVLKDGEIVVKDGEVVASP-HGR 516
>4H9M-A nrPDB
Length = 840
Score = 55.9 bits (133), Expect = 5e-08, Method: Composition-based stats.
Identities = 22/106 (20%), Positives = 39/106 (36%), Gaps = 19/106 (17%)
Query: 2 AAPSRLLIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGA--------PAGLRVLD 53
A +I +++ AD+ ++DG++ ++G P A V+
Sbjct: 334 AISLDTVITNAVIIDYTGIIKADIGIKDGLIASIGKAGNPDIMNGVFSNMIIGANTEVIA 393
Query: 54 AAGKLVLPGGIDTHTHMQFPFMGSRSIDDFHQGTKAALSGGTTMII 99
G +V G ID H H P + A+S G T ++
Sbjct: 394 GEGLIVTAGAIDCHVHYICPQLVYE-----------AISSGITTLV 428
Score = 35.1 bits (79), Expect = 0.083, Method: Composition-based stats.
Identities = 18/83 (21%), Positives = 26/83 (31%), Gaps = 22/83 (26%)
Query: 368 KMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTHHQAVNFNI 427
R++A + N A G + VG AD+V+W P
Sbjct: 670 NFRIRRYIAKYTINPAIANGFSQYVGSVEVGKLADLVMWKPS------------------ 711
Query: 428 FEGMVCHGVPLVTISRGKVVYEA 450
F G P + I G V +
Sbjct: 712 FFGTK----PEMVIKGGMVAWAD 730
>4R7W-A nrPDB
Length = 431
Score = 55.5 bits (132), Expect = 5e-08, Method: Composition-based stats.
Identities = 65/453 (14%), Positives = 125/453 (27%), Gaps = 65/453 (14%)
Query: 9 IRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGIDTHT 68
I R+ + D+ +DG++ + +DA G+L +P ++ H
Sbjct: 3 IINARLRRQEALFTLDL--QDGIIHRITAQAAMQTADAGA---IDAQGRLAIPPFVEPHI 57
Query: 69 HMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWADPKVCCD 128
H+ + GT L G T +
Sbjct: 58 HLDATLTAGEP-EWNRSGT---LFEGITRWSQRKASITPEDTRQRALKTIGMLRDFGVQH 113
Query: 129 YSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEAFSRCKEIGAI 188
HV VT S + + + Q+ +A+ + + E +R E+GA
Sbjct: 114 VRTHVDVTDPSLAALQALLAVKQEAADLIDLQIVAFPQEGIESYPNGRELMTRAIEMGAD 173
Query: 189 AQ---VHAENG-----DLIAEGAKKMLALGI-TGPEGHELCRPEAVEAEATLRAITIASA 239
H EN + G E+ P++ E +
Sbjct: 174 VVGGIPHYENTRDKGVSSVMFLMDLAQRYGRLVDVHCDEIDDPQSRFLEVLAEEARVRG- 232
Query: 240 VNCPLYIVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHA---AHHV 296
+ + H + + Y + L G ++ +
Sbjct: 233 MGAQVTASHTCAMGSYD----------NAYCSKLFRLLKASGINFISCPTESIHLQGRFD 282
Query: 297 MGPPLRPDPSTPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRM 356
P R + + D + LG + +I + + +
Sbjct: 283 SWPKRRGVTRVAELDRAGIN----VCFAQD--SIQDPWYPLGNGNILRILDAGLHICHML 336
Query: 357 SVIWEKGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISA 416
G D R + + N+A+ L G +A G A+++I D +
Sbjct: 337 ----------GYDDLQRCLDFVTDNSARALCLGDNYG-LAEGRPANLLILDAE------- 378
Query: 417 KTHHQAVNFNIFEGMVCHGVPLVTISRGKVVYE 449
N +E + L +I GKV+ +
Sbjct: 379 ---------NDYEAVRRQARVLTSIRHGKVILQ 402
>5XGX-A nrPDB
Length = 395
Score = 55.1 bits (131), Expect = 7e-08, Method: Composition-based stats.
Identities = 71/420 (16%), Positives = 122/420 (29%), Gaps = 68/420 (16%)
Query: 7 LLIRGGRVVNDDFSEVADVLVEDGVVRAL---GHDLLPPGGAPAGLRVLDAAGKLVLPGG 63
+L+ + + + DVL+ + A+ G + ++V++ G ++ PG
Sbjct: 9 ILLCNVNIYAPNPLGIKDVLIAGNKIAAIYDHGQGEITIPKQWP-VKVINFDGAILTPGF 67
Query: 64 IDTHTHMQFPFMGSRSIDDFHQ-----GTKAALSGGTTMIIDFA----IPQKGGSLIEAF 114
ID+H H+ G F G G T ++ + +L+
Sbjct: 68 IDSHAHI----TGGGGQAGFATQVPPVGLTEFTHAGVTTVVGLLGTDDTTRSTENLLSRV 123
Query: 115 ETWRSWADPKVCCDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLE 174
R C H +T + K ++ L G+ F + + T E
Sbjct: 124 YGLREEGLSAYCWTGGYHFPLTTITGSAKSDIAFLEPVIGIGEFAI--SDHRSSQPTFEE 181
Query: 175 LYEAFSRCKEIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAI 234
+ S G I G G L E E RAI
Sbjct: 182 VIRLASETHVAGLIT--------------------GKAGVIHFHLGDGER-RLELIERAI 220
Query: 235 TIASAVNCPLYIVHVM-SKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAA 293
HV +K + G L W
Sbjct: 221 RETELPARVFNPTHVNRNKPLFEDSCKLLSKG-------CHIDLTAFPAGTAQPGWEACD 273
Query: 294 HHVMGPPLRPDPSTPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVE 353
M L + L++ G Q L DF + + +
Sbjct: 274 AIEMA------VERQLPLEQI----TLSSDGGGCLPCFDPQGELQHMDFGRA----STLG 319
Query: 354 DRMSVIWEKGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRT 413
+ + KG + + + ++N A I + KG+IAVG DAD+++ + K T
Sbjct: 320 ETLVATLNKG-----LSLETVLPMLTSNVANILR-FKNKGQIAVGFDADLLVMNEKYEIT 373
>1O12-A nrPDB
Length = 376
Score = 55.1 bits (131), Expect = 7e-08, Method: Composition-based stats.
Identities = 78/456 (17%), Positives = 143/456 (31%), Gaps = 107/456 (23%)
Query: 7 LLIRGGRVVND-DFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGID 65
+++ +V+ D DV +E+G + + P G +++PG +D
Sbjct: 13 MIVEKVLIVDPIDGEFTGDVEIEEGKIVKVEKRECIPRG-------------VLMPGFVD 59
Query: 66 THTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWA-DPK 124
H H DF + + S G T + + + E R + +
Sbjct: 60 PHIH--GVVGADTMNCDFSEMEEFLYSQGVTTFLATTVSTSLEKMKEILRKARDYILENP 117
Query: 125 VCCDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEAFSRCKE 184
+H+ + S + KG +S K + ++ EL E S K
Sbjct: 118 STSLLGVHLEGPYISKE----------KKGAHSEKH------IRPPSERELSEIDSPAKM 161
Query: 185 IGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVE---AEATLRAITIASAVN 241
+ ++ E+ +L+ K+ I GH + E E R + +
Sbjct: 162 LTFAPEI--ESSELLLRLVKR----DIVLSAGHSIATFEEFMKFYKEGVKRITHFPNGLK 215
Query: 242 CPLYIVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMGPPL 301
PL+ H + G + + + L DG H + +
Sbjct: 216 -PLH--H----------REIGITGAGLLLDDVKLELICDGVHLSREMVKLVYKVKKANGI 262
Query: 302 RPDPSTPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRM----S 357
+ L + TT G D K+ +GV +ED +
Sbjct: 263 VLVTDSISA--AGLKDGT-TTLG---------------DLVVKVKDGVPRLEDGTLAGST 304
Query: 358 VIWEKGVHS-GKMD---ENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRT 413
+ + + V + K V+S N+ L +GRIA G+ AD+V+ D
Sbjct: 305 LFFSQAVKNFRKFTGCSITELAKVSSYNSCVELGL-DDRGRIAEGTRADLVLLDEDL--- 360
Query: 414 ISAKTHHQAVNFNIFEGMVCHGVPLVTISRGKVVYE 449
++TI G+VV+
Sbjct: 361 ----------------------NVVMTIKEGEVVFR 374
>5VGM-A nrPDB
Length = 345
Score = 54.7 bits (130), Expect = 9e-08, Method: Composition-based stats.
Identities = 49/283 (17%), Positives = 85/283 (30%), Gaps = 48/283 (16%)
Query: 65 DTHTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSW---A 121
D H H++ + + ++ D + AL + E +R A
Sbjct: 14 DWHVHLRDGDVLADTVRDISRYNGRALI--------MPNTVPPVTTTEMALAYRERIMAA 65
Query: 122 DPKVCCDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMA----YKDLYMVTDLELYE 177
P+ + +A+ + EE++ V + K++ A D + + +Y
Sbjct: 66 QPQAH--FEPLMALYLTDNTSPEEIRKAKASGKVVAAKLYPAGATTNSDSGVTSAKNIYP 123
Query: 178 AFSRCKEIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIA 237
+E+G + VH E +T E R E T +A
Sbjct: 124 VLQAMQEVGMLLLVHGE----------------VTTHEVDIFDR------EKTFLDTVLA 161
Query: 238 SAVN--CPLYIV--HVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAA 293
VN L IV H+ + A + A G V A L + H
Sbjct: 162 PIVNDFPQLKIVLEHITTADAVTFVQQA---GDNVAATITAHHLLFNRNHMLVGGIRP-- 216
Query: 294 HHVMGPPLRPDPSTPDFLMNLLANDDLTTTGTDNCTFNTCQKA 336
H P L+ + + GTD+ +K
Sbjct: 217 HFYCLPILKRATHQHALVAAATSGSKKFFLGTDSAPHAKGRKE 259
>4G7E-B nrPDB
Length = 840
Score = 54.3 bits (129), Expect = 1e-07, Method: Composition-based stats.
Identities = 20/106 (18%), Positives = 38/106 (35%), Gaps = 19/106 (17%)
Query: 2 AAPSRLLIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPP--------GGAPAGLRVLD 53
A +I +++ AD+ ++DG++ ++G P V+
Sbjct: 334 ALSLDTVITNAVIIDYSGIIKADIGIKDGLIHSIGKSGNPDVMDGVFQNMTTGVNTEVIA 393
Query: 54 AAGKLVLPGGIDTHTHMQFPFMGSRSIDDFHQGTKAALSGGTTMII 99
G +V G ID H H P + A++ G T ++
Sbjct: 394 GEGLIVTAGAIDCHVHYICPQLVYE-----------AVTSGITTLV 428
Score = 38.1 bits (87), Expect = 0.010, Method: Composition-based stats.
Identities = 28/151 (18%), Positives = 48/151 (31%), Gaps = 27/151 (17%)
Query: 368 KMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTHHQAVNFNI 427
R+VA + N A G + VG AD+V+W P
Sbjct: 670 NFRIKRYVAKYTINPAIANGFSQYVGSVEVGKLADLVMWKPSF----------------- 712
Query: 428 FEGMVCHGVPLVTISRGKVVYEA-GVFSVTAGDGKFIPRKPFAEYIYKRIKQRDRTCTPT 486
P + I G+V Y G + + + + +P +Y + + +
Sbjct: 713 -----FGAKPEMVIKGGEVAYANMGDPNASIPTPEPVKMRP----MYGALGKAGGALSIA 763
Query: 487 PVERAPYKGEVATLKSRVTKEDATAGTRKQA 517
V +A V L + +A + RK
Sbjct: 764 FVSKAALDQRVKVLYGLNKRVEAVSNVRKLT 794
>3N2C-A nrPDB
Length = 423
Score = 52.8 bits (125), Expect = 4e-07, Method: Composition-based stats.
Identities = 77/414 (18%), Positives = 128/414 (30%), Gaps = 88/414 (21%)
Query: 24 DVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGIDTHTHMQFPFMGSRSIDDF 83
V+++ + + + +D GK V+PG ID H H+ + ++
Sbjct: 26 HVVIDGERIVEVTD----RPVDLPNAQAIDVRGKTVMPGFIDCHVHV-LASNANLGVNAT 80
Query: 84 HQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWADPKVCCDYSLHVAVT---WWSD 140
AA+ ++P L F + R D+SL AV
Sbjct: 81 QPNILAAIR---------SLPILDAMLSRGFTSVRDAGG----ADWSLMQAVETGLVSGP 127
Query: 141 QVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEAFSRCKEIGAIAQV--------H 192
++ K L Q G F+ +L E S C GAIA+V
Sbjct: 128 RIFPSGKALSQTGGHGDFR-----------PRGDLLEPCSCCFRTGAIARVVDGVEGVRL 176
Query: 193 AENGDLIAEGAK-KMLALGI----TGPEG-----HELCRPEAVEAEATLRAIT---IASA 239
A ++ + K++A G T P + R EAEA +
Sbjct: 177 AVREEIQKGATQIKIMASGGVASPTDPIANTQYSEDEIRAIVDEAEAANTYVMAHAYTGR 236
Query: 240 VNCPLYIVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMGP 299
V + ++ +A +G + +L T ++ H A M P
Sbjct: 237 AIARAVRCGVRTIEHGNLVDEAAAKLMHEHGAFVVPTLVT-----YDALAKHGAEFGM-P 290
Query: 300 P------LRPDPSTPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVE 353
P + L G+D A +F + +E
Sbjct: 291 PESVAKVASVQQKGRESLEIYANAGVKMGFGSD---LLGEMHAFQSGEFRIRAEVLGNLE 347
Query: 354 DRMSVIWEKGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWD 407
+ +T AA+I N+ + G IAVG+ AD+V+ D
Sbjct: 348 A--------------------LRSATTVAAEIVNMQGQLGVIAVGAIADLVVLD 381
>4DYK-A nrPDB
Length = 451
Score = 52.0 bits (123), Expect = 6e-07, Method: Composition-based stats.
Identities = 68/458 (14%), Positives = 128/458 (27%), Gaps = 97/458 (21%)
Query: 25 VLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGIDTHTHMQF------------ 72
+ + DG + + + + G L+ PG ++ H H
Sbjct: 32 LGIRDGQIALVAPREQAMRHG--ATEIRELPGMLLAPGLVNAHGHSAMSLFRGLADDLPL 89
Query: 73 ---------PFMGSRSIDDF-HQGTKAALS----GGTTMIIDFAIPQKGGSLIEAFETWR 118
P G +DF GT+ A++ GG T D ++
Sbjct: 90 MTWLQDHIWPAEGQWVSEDFIRDGTELAIAEQVKGGITCFSDMYF--YPQAICGVVHDSG 147
Query: 119 SWADPKVCCDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEA 178
A + ++ +++ M + K ++ Y V+D +L +
Sbjct: 148 VRAQVAIPVLDFPIPGARDSAEAIRQGMALFDDLKHHPRIRIAFGPHAPYTVSDDKLEQI 207
Query: 179 FSRCKEIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIAS 238
+E+ A Q+H + E + M G L R R +
Sbjct: 208 LVLTEELDASIQMHVH--ETAFEVEQAMERNGER-----PLAR--------LHRLGLL-- 250
Query: 239 AVNCPLYIVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMG 298
VH+ + + V++ P + G K W + +G
Sbjct: 251 --GPRFQAVHMTQVDNDDLAMLVETNSSVIHC-PESNLKLASGFCPVEKLWQAGVNVAIG 307
Query: 299 PPLRPDPSTPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSV 358
+N+DL G E R +
Sbjct: 308 ------------TDGAASNNDLDLLG----------------------------ETRTAA 327
Query: 359 IWEKGV--HSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISA 416
+ K V + +D +R + + + N A+ L G + G AD+V +D G
Sbjct: 328 LLAKAVYGQATALDAHRALRMATLNGARALGLERLIGSLEAGKAADLVAFDLSGLAQQPV 387
Query: 417 KTHHQAVNFNIFEGMVCHGVPLVTISRGKVVYEAGVFS 454
+ + G C G+ + + G
Sbjct: 388 YDPVSQLIYAS--GRDC---VRHVWVGGRQLLDDGRLL 420
>4LH8-A nrPDB
Length = 469
Score = 52.0 bits (123), Expect = 6e-07, Method: Composition-based stats.
Identities = 28/96 (29%), Positives = 45/96 (46%), Gaps = 11/96 (11%)
Query: 7 LLIRG-GRVVNDDFSEV----ADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLP 61
+LIRG RV+ D E AD+L++ + A+G +L + R +D G + LP
Sbjct: 15 ILIRGLTRVITFDDQERELEDADILIDGPKIVAVGKNLSD----RSVSRTIDGRGMIALP 70
Query: 62 GGIDTHTHMQFPFMGSRSIDDFHQGTKAALSGGTTM 97
G I++H H+ R+I + T A+ G
Sbjct: 71 GLINSHQHLYE--GAMRAIPQLERVTMASWLEGVLT 104
>4F0R-A nrPDB
Length = 447
Score = 51.6 bits (122), Expect = 8e-07, Method: Composition-based stats.
Identities = 74/463 (15%), Positives = 132/463 (28%), Gaps = 109/463 (23%)
Query: 25 VLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGIDTHTHMQF------------ 72
+ + DG + A+ G L+ +++PG I+ H H
Sbjct: 30 IAIRDGKIAAIIPAADAAG--LEADERLELPDHVLMPGLINLHGHSAMSLLRGLADDKAL 87
Query: 73 ---------PFMGSRSIDDF-HQGTKAA----LSGGTTMIIDFAIPQKGGS---LIEAFE 115
P G DDF G+ A + GGTT I D + L
Sbjct: 88 MDWLTNYIWPTEGKHVHDDFVFDGSLLAMGEMIRGGTTTINDMYFYNAAVARAGLASGMR 147
Query: 116 TWRSWADPKVCCDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLEL 175
T+ + + +Y+ + D + + M Q G + +A Y V+D
Sbjct: 148 TFVGCSILEFPTNYA-----SNADDYIAKGMAERSQFLGEDLLTFTLAPHAPYTVSDDTF 202
Query: 176 YEAFSRCKEIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAIT 235
+ + ++ + H + E + G L R R
Sbjct: 203 RKVVTLAEQEDMLI--HCHIHETADEVNNSVKEHGQR-----PLAR--------LQRLGL 247
Query: 236 IASAVNCPLYIVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHH 295
++ + ++VH+ + A R G L T N +
Sbjct: 248 LSPRLVA-AHMVHLNDAE----VELAARHG-----------LSTAHNPASNMKLASG--- 288
Query: 296 VMGPPLRPDPSTPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDR 355
+ P + +A GTD N K D E R
Sbjct: 289 -ISP-------VSKLMDAGVAVG----IGTDGAASN------NKLDMLA--------ETR 322
Query: 356 MSVIWEKGVHSGKMDENRF-----VAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKG 410
++ + K G +D + + + N A+ + + G + VG AD++ D
Sbjct: 323 LAALLAKV---GTLDPTSVPAAAAIRMATLNGARALGIADKVGSVKVGKQADLIALDLAQ 379
Query: 411 TRTISAKTHHQAVNFNIFEGMVCHGVPLVTISRGKVVYEAGVF 453
T A V + G +G+ +
Sbjct: 380 LETAPAFDPISHVVYA--AGRE---QVSHVWVKGRALMRERKL 417
>4WHB-E nrPDB
Length = 461
Score = 50.9 bits (120), Expect = 1e-06, Method: Composition-based stats.
Identities = 62/460 (13%), Positives = 127/460 (27%), Gaps = 92/460 (20%)
Query: 5 SRLLIRGGRVVNDDFSEV---ADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLP 61
S + I +++ V+VE +G P P G V+D + ++P
Sbjct: 2 STIAITNVTLIDGLGGLPRPATTVIVEGDRFATVGPSDSTP--VPEGATVVDGNRRWMVP 59
Query: 62 GGIDTHTHMQFPFM--------------GSRSIDDFHQGTKAALSGGTTMIIDFAIPQKG 107
G ++ + H+ +M R ++ + + AL G T + D
Sbjct: 60 GYVNGNVHLLDAWMFMAGPGTIEYLARWEGRYVEVIEEAAQLALRNGVTTVFD--THNAI 117
Query: 108 GSLIEAFETWRSWADPKVCCDYS-------------LHVAVTWWSDQVKEEMKILVQDKG 154
++ A + + + H A + + + + + G
Sbjct: 118 EPVLAARDRINAGISQGARIFAAGTIVGMGGPFSADFHFAGRTAATRTFVDRIDSMFEAG 177
Query: 155 VNSFKMFMAYKDLYMVTDLELYEAFSRCKEIGAIAQVHAENGDLIAEGAKKMLALGITGP 214
V + K++ L K H ++ + + +
Sbjct: 178 VGHQLSLLPRKEVRARVRDYLSRGVDMLK---IAVSDH-----IVFTLVDRSVGFDRS-- 227
Query: 215 EGHELCRPEAVEAEATLRAITIASAVNCPLYIVHVMSK---SAAKVIADARRDGKVVYGE 271
RP RA P+ V + ++ ++ AD G+
Sbjct: 228 -YQTFSRPVLEVMVEEARA------AGVPVLTHSVSVEALDTSVELGADVLIHANYTLGQ 280
Query: 272 PIAASL---------------GTDGTHYWNKEWHHAAHHVMGPPLRPDPSTPDFLMN-LL 315
I L D ++ A + G P + +L
Sbjct: 281 EIPNYLIDKIVASDSWAGLQTVHDQHRQGLEDVGSWAAALAGEPYATNERNLISANAKIL 340
Query: 316 ANDDLTTTGTDN-CTFNTCQKA-----LGKDDFTKIPNGVNGVEDRMSVIWEKGVHSGKM 369
N D D+ + ++ +G D F W + + M
Sbjct: 341 LNTDAGCPSKDHLADLSPVEREDRPWTIGNDHFH----------------WTQSMVEKGM 384
Query: 370 DENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPK 409
++ + N A+ + + G + G AD V+ D
Sbjct: 385 SPLEAISAATINVARAYGKADQIGSVETGKLADFVLLDQD 424
>3MTW-A nrPDB
Length = 403
Score = 50.5 bits (119), Expect = 2e-06, Method: Composition-based stats.
Identities = 81/470 (17%), Positives = 132/470 (28%), Gaps = 101/470 (21%)
Query: 3 APSRLL-IRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLP 61
+ +RLL + G+ V++ V+V DG + ++G PAG +D G +LP
Sbjct: 7 SAARLLDVASGKYVDNPL-----VIVTDGRITSIGKK---GDAVPAGATAVDLPGVTLLP 58
Query: 62 GGIDTHTHMQ-----FPFMGSRSIDDFHQGTKAA-----LSGGTTMIIDFAIPQ-KGGSL 110
G ID H H+ + D F + A L G T + + L
Sbjct: 59 GLIDMHVHLDSLAEVGGYNSLEYSDRFWSVVQTANAKKTLEAGFTTVRNVGAADYDDVGL 118
Query: 111 IEAFETWRSWADPKVCCDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMV 170
EA + + ++ T F M K+ +
Sbjct: 119 REAIDA--GYVPGPRIVTAAISFGATGGHCDS-------------TFFPPSMDQKNPFNS 163
Query: 171 T-DLELYEAFSRCKEIGAIAQVHAENGDLIAEG------AKKMLALGITGPEGHELCRPE 223
E +A K+ GA G + + G + E H
Sbjct: 164 DSPDEARKAVRTLKKYGAQVIKICATGGVFSRGNEPGQQQLTYEEMKAVVDEAHMAGIKV 223
Query: 224 AVEAEATLRAITIASAVNCPLYIVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTH 283
A A I A I H + I A + G A D +
Sbjct: 224 AAHAHGAS-GIREAVRAGVDT-IEHASLVDD-EGIKLAVQKG---------AYFSMDIYN 271
Query: 284 YWNKEWHHAAHHVMGPPLRPDPS----TPDFLMNLLANDDLTTTGTDNCTFNTCQKALGK 339
+ + V+ LR D + L GTD +
Sbjct: 272 TDYTQAEGKKNGVLEDNLRKDRDIGELQRENFRKALKAGVKMVYGTDAGIY--------- 322
Query: 340 DDFTKIPNGVNGVEDRMSVIWEKGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGS 399
P+G N + + V + + + + AA+ G++AVG
Sbjct: 323 ------PHGDNAKQFAVMVRY-------GATPLQAIQSATLTAAEALGRSKDVGQVAVGR 369
Query: 400 DADIVIW--DPKGTRTISAKTHHQAVNFNIFEGMVCHGVPLVTISRGKVV 447
D++ DP + E P+ + G VV
Sbjct: 370 YGDMIAVAGDP-------------LADVTTLE------KPVFVMKGGAVV 400
>6NBO-A nrPDB
Length = 402
Score = 48.2 bits (113), Expect = 1e-05, Method: Composition-based stats.
Identities = 24/71 (33%), Positives = 33/71 (46%), Gaps = 7/71 (9%)
Query: 7 LLIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGIDT 66
LLIR R DD D+L+E + G L AP G + + AG + LPG ++
Sbjct: 12 LLIRNVRTGADDAL---DILIEGDRIARTGPSL----DAPPGCAIEEGAGAIALPGLVEG 64
Query: 67 HTHMQFPFMGS 77
HTH+ G
Sbjct: 65 HTHLDKTHWGM 75
>1YRR-A nrPDB
Length = 382
Score = 45.5 bits (106), Expect = 6e-05, Method: Composition-based stats.
Identities = 75/432 (17%), Positives = 130/432 (30%), Gaps = 94/432 (21%)
Query: 12 GRVVNDDFSEVAD--VLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGIDTH-- 67
GR+ + D V++ DG+++++ P P + G ++ PG ID
Sbjct: 7 GRIFT-GHEFLDDHAVVIADGLIKSV----CPVAELPPEIEQRSLNGAILSPGFIDVQLN 61
Query: 68 ----THMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWADP 123
+ S++ KA G T + I + + R +
Sbjct: 62 GCGGVQFNDT-AEAVSVETLEIMQKANEKSGCTNYLPTLITTSDELMKQGVRVMREYLAK 120
Query: 124 KVCCDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEAFSRCK 183
LH+ W + + KG ++ F+ D +V L
Sbjct: 121 HPNQALGLHLEGPWLN----------LVKKGTHN-PNFVRKPDAALVDFL---------- 159
Query: 184 EIGAIAQVHAENGDLI-----------AEGAKKMLALGITGPEGHELCRPEAVEAEATLR 232
EN D+I AE K+ GI GH EA+A R
Sbjct: 160 ---------CENADVITKVTLAPEMVPAEVISKLANAGIVVSAGH--SNATLKEAKAGFR 208
Query: 233 A-ITIASAVNCPLYIVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHH 291
A IT A H+ + + G ++ I + DG H +
Sbjct: 209 AGITFA---------THLYNAMPYITGREPGLAGAILDEADIYCGIIADGLHVDYANIRN 259
Query: 292 AAHHVMGPPLRPDPSTPDFLMNLLANDDLTTTGTDNCTFNTCQ-----KALGKDDFTKIP 346
A L+ D L T T N Q K + + +
Sbjct: 260 AKR------LKGDKL------------CLVTDATAPAGANIEQFIFAGKTIYYRNGLCVD 301
Query: 347 NGVNGVEDRMSVI--WEKGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIV 404
+++I V + + + + + A+ + R G +A G A++
Sbjct: 302 ENGTLSGSSLTMIEGVRNLVEHCGIALDEVLRMATLYPARAIGVEKRLGTLAAGKVANLT 361
Query: 405 IWDPK--GTRTI 414
+ P T+TI
Sbjct: 362 AFTPDFKITKTI 373
>2OOF-A nrPDB
Length = 416
Score = 45.1 bits (105), Expect = 7e-05, Method: Composition-based stats.
Identities = 73/423 (17%), Positives = 124/423 (29%), Gaps = 79/423 (18%)
Query: 25 VLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGIDTHTHMQFPFMGSRSIDDFH 84
+ V +G + AL G PA + D GKLV PG ID HTH+
Sbjct: 32 LGVHEGRIHALVPMQDLKGPYPAHWQ--DMKGKLVTPGLIDCHTHL------------IF 77
Query: 85 QGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRS-----WADPKVCCDYSLHVAVTWWS 139
G++A +F + QKG E A D +A+
Sbjct: 78 AGSRAE---------EFELRQKGVPYAEIARKGGGIISTVRATRAASEDQLFELALPRVK 128
Query: 140 DQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEAFSRCKEIGAIAQVHAENGDLI 199
++E GV + ++ K Y +T + + + +G +
Sbjct: 129 SLIRE---------GVTTVEI----KSGYGLTLEDELKMLRVARRLGEALPI-------- 167
Query: 200 AEGAKKMLALGITGPEG--HELCRPEAVEAEATLRAITIASAVNCPLYIVHV--MSKSAA 255
+LA PE E + E A A ++ H+
Sbjct: 168 -RVKTTLLAAHAVPPEYRDDPDSWVETICQEIIPAAAEAGLADAVDVFCEHIGFSLAQTE 226
Query: 256 KVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMGPPLRPDPSTPDFLMNLL 315
+V A + G V G L G + + + + P+ + L
Sbjct: 227 QVYLAADQYGLAVKG--HMDQLSNLGGSTLAANFGALSVDHL------EYLDPEGIQALA 278
Query: 316 ANDDLTTTGTDNCTFNTCQKALGKDDFTKI-----------PNGVNGVEDRMSVIWEKGV 364
+ T F K K P V RM++
Sbjct: 279 HRGVVATLLPTAFYFLKETKLPPVVALRKAGVPMAVSSDINPGTAPIVSLRMAM--NMAC 336
Query: 365 HSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWD----PKGTRTISAKTHH 420
+ +A + +AA+ + G++ VG AD ++W+ + + I
Sbjct: 337 TLFGLTPVEAMAGVTRHAARALGEQEQLGQLRVGMLADFLVWNCGHPAELSYLIGVDQLV 396
Query: 421 QAV 423
V
Sbjct: 397 SRV 399
>3GGM-A nrPDB
Length = 81
Score = 44.7 bits (104), Expect = 1e-04, Method: Composition-based stats.
Identities = 16/66 (24%), Positives = 33/66 (50%), Gaps = 3/66 (4%)
Query: 7 LLIRGGRVVNDDFSEV--ADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGI 64
+++ G++ D S+ + + + DG++ A+G D L + +D K +PG
Sbjct: 6 MILYNGKITTLDPSQPEVSAIAITDGLITAVGGDELLNSATEKTKK-IDLKRKRAIPGLN 64
Query: 65 DTHTHM 70
D+H H+
Sbjct: 65 DSHIHV 70
>3IGH-X nrPDB
Length = 486
Score = 43.5 bits (101), Expect = 2e-04, Method: Composition-based stats.
Identities = 18/81 (22%), Positives = 33/81 (40%), Gaps = 4/81 (4%)
Query: 4 PSRLLIRGGRVVND--DFSEVADVLVEDGVVRALGHDLLPPG-GAPAGLRVLDAAGKLVL 60
+ LI G + +V+ +++ G V G + +G ++D GK V+
Sbjct: 2 SLKALI-NGTIYTSFNPLKKVSGLVISHGKVIYAGDSEVAKKIVELSGGEIVDLKGKYVM 60
Query: 61 PGGIDTHTHMQFPFMGSRSID 81
P D+H H+ M +D
Sbjct: 61 PAFFDSHLHLDELGMSLEMVD 81
>4LFY-A nrPDB
Length = 372
Score = 43.1 bits (100), Expect = 3e-04, Method: Composition-based stats.
Identities = 42/284 (14%), Positives = 78/284 (27%), Gaps = 44/284 (15%)
Query: 65 DTHTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWADPK 124
D H H++ D + I + + + +R
Sbjct: 37 DWHLHLRD--------GDMLAAVLPHTARQFGRAIVMPNLKPPVTTTAQAQAYRERILAA 88
Query: 125 VCCDYSLHVAVT-WWSDQVKEEMKILVQDKG-VNSFKMFMA----YKDLYMVTDLELYEA 178
+ + +T + +D + ++ G V+ K++ A D + + +
Sbjct: 89 LPAGMTFEPLMTLYLTDNTPPDEIRRARESGFVHGVKLYPAGATTNSDHGVTDLAKCAKT 148
Query: 179 FSRCKEIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIAS 238
+E G VH E +T R E R +T
Sbjct: 149 LEAMQETGMPLLVHGE----------------VTDASIDLFDR----EKVFIDRVMTPLR 188
Query: 239 AVNCPLYIV--HVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAA--- 293
L +V H+ +K AA + DA + G I A Y
Sbjct: 189 RDFPGLKVVFEHITTKDAADYVRDADAA-PGLLGATITAH----HLLYNRNALFVGGIRP 243
Query: 294 HHVMGPPLRPDPSTPDFLMNLLANDDLTTTGTDNCTFNTCQKAL 337
H+ P L+ + + + + GTD+ K
Sbjct: 244 HYYCLPVLKRETHRVALVEAATSGNPRFFLGTDSAPHARDAKET 287
>3ICJ-A nrPDB
Length = 534
Score = 42.8 bits (99), Expect = 3e-04, Method: Composition-based stats.
Identities = 18/79 (22%), Positives = 32/79 (40%), Gaps = 4/79 (5%)
Query: 6 RLLIRGGRVVND--DFSEVADVLVEDGVVRALGHD-LLPPGGAPAGLRVLDAAGKLVLPG 62
+ LI G + +V+ +++ + V G AG ++D GK V+P
Sbjct: 38 KALI-NGTIYTSFSPVKKVSGLVISNERVLYAGDSSTALRIAELAGGEIIDLKGKFVMPA 96
Query: 63 GIDTHTHMQFPFMGSRSID 81
D+H H+ M +D
Sbjct: 97 FFDSHLHLDELGMSLEMVD 115
>2QS8-A nrPDB
Length = 418
Score = 42.8 bits (99), Expect = 4e-04, Method: Composition-based stats.
Identities = 80/478 (16%), Positives = 149/478 (31%), Gaps = 119/478 (24%)
Query: 5 SRLLIRGGRVVN---DDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLP 61
S+ LI G++++ D ++++ ++ + + +D VLP
Sbjct: 7 SKTLIHAGKLIDGKSDQVQSRISIVIDGNIISDIKKGFISSND---FEDYIDLRDHTVLP 63
Query: 62 GGIDTHTHM-QFPFMGSRSIDDFHQGTKAALS---------GGTTMIIDFAIPQKGG-SL 110
G +D H H Q +++ + +A L+ G T + SL
Sbjct: 64 GLMDMHVHFGQEYQSKAQAPIKVEREMQAILATQHAYVTFKSGFTTVRQVGDSGLVAISL 123
Query: 111 IEAFETW-----RSWADPKVCCDYSLHVAVTWWSDQVKEEMKILVQDKGVNS--FKMFMA 163
+A + R +A K H T + + ++ V ++GV + ++++ A
Sbjct: 124 RDAINSGKLAGPRIFAAGKTIATTGGHADPT--NGKAVDDYDYPVPEQGVVNGPYEVYAA 181
Query: 164 ----YKDLY---------------------MVTDLELYEAFSRCKEIGAIAQVHAENGDL 198
YKD T E+ S K+ G VHA +
Sbjct: 182 VRQRYKDGADGIKITVTGGVLSVAKSGQNPQFTQEEVDAVVSAAKDYGMWVAVHAHGAE- 240
Query: 199 IAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAVNCPLYIVHVMSKSAAKVI 258
G K+ + G+ E ++ EA I N Y V + SA + +
Sbjct: 241 ---GMKRAIKAGVDSIE-----HGTFMDLEAMDLMIE-----NGTYY---VPTISAGEFV 284
Query: 259 ADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMGPPLRPDPSTPDFLMNLLAND 318
A+ + + E +GP + D
Sbjct: 285 AEKSK------------------IDNFFPEIVRPKAASVGPQIS------DTFRKAYEKG 320
Query: 319 DLTTTGTDNCTFNTCQK-ALGKDDFTKIPNGVNGVEDRMSVIWEKGVHSGKMDENRFVAV 377
GTD QK +F + VE+ M + + +
Sbjct: 321 VKIAFGTD----AGVQKHGTNWKEFVYM------VENGMPAM-------------KAIQS 357
Query: 378 TSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTHHQAVNFNIFEGMVCHG 435
+ AK+ + + G I G AD++ IS + V+ I +G++ G
Sbjct: 358 ATMETAKLLRIEDKLGSIESGKLADLIAVKGNPIEDISV---LENVDVVIKDGLLYEG 412
>1R9X-A nrPDB
Length = 430
Score = 42.8 bits (99), Expect = 4e-04, Method: Composition-based stats.
Identities = 33/241 (13%), Positives = 77/241 (31%), Gaps = 46/241 (19%)
Query: 1 MAAPSRLLIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVL 60
MA + I R+ ++ + ++DG + A+ G P LDA LV+
Sbjct: 4 MANNALQTIINARLPGEEGLWQ--IHLQDGKISAIDAQ---SGVMPITENSLDAEQGLVI 58
Query: 61 PGGIDTHTHMQFPFMGSRS----IDDFHQGT-----KAAL------------------SG 93
P ++ H H+ + +G + AL +
Sbjct: 59 PPFVEPHIHLDTTQTAGQPNWNQSGTLFEGIERWAERKALLTHDDVKQRAWQTLKWQIAN 118
Query: 94 GTTMIIDFA-IPQKGGSLIEAFETWRSWADPKVCCD-----YSLHVAVTWWSDQVKEEMK 147
G + + + ++A + P D + +++ + + E
Sbjct: 119 GIQHVRTHVDVSDATLTALKAMLEVKQEVAP--WIDLQIVAFPQEGILSYPNGEALLEEA 176
Query: 148 ILVQDKGVNSFKMFMAYKDLYMVTDLELYEAFSRCKEIGAIAQVHAENGDLIAEGAKKML 207
+ + V + F ++ + L++ F+ ++ + VH D I + + +
Sbjct: 177 LRLGADVVGAIPHFEFTREYGV---ESLHKTFALAQKYDRLIDVHC---DEIDDEQSRFV 230
Query: 208 A 208
Sbjct: 231 E 231
>2P9B-A nrPDB
Length = 458
Score = 42.0 bits (97), Expect = 6e-04, Method: Composition-based stats.
Identities = 17/64 (26%), Positives = 27/64 (42%), Gaps = 12/64 (18%)
Query: 7 LLIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGIDT 66
++R +V DG + + + PA LD GK+V+PG I+
Sbjct: 29 TILRNMTIVVG----------ADGRIEQVAPSIETS--IPAEYHYLDGTGKIVMPGLINA 76
Query: 67 HTHM 70
HTH+
Sbjct: 77 HTHL 80
Score = 28.9 bits (63), Expect = 5.1, Method: Composition-based stats.
Identities = 15/92 (16%), Positives = 28/92 (30%), Gaps = 17/92 (18%)
Query: 360 WEKGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTH 419
E V + + A I + G + VG AD+++ +
Sbjct: 360 LELLVAYAGFSPAEALHAATAVNASILGVDAETGSLEVGKSADLLVLNA----------- 408
Query: 420 HQAVNFNIFEGMVCHGVPLVTISRGKVVYEAG 451
N + + P + I+ G V+ G
Sbjct: 409 ------NPLDDLRALEHPALVIAAGHPVWRPG 434
>3LNP-A nrPDB
Length = 468
Score = 41.6 bits (96), Expect = 8e-04, Method: Composition-based stats.
Identities = 34/206 (16%), Positives = 72/206 (34%), Gaps = 50/206 (24%)
Query: 25 VLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGIDTHTHM----------QFPF 74
+L++DG++ A+ LD ++++PG ++ H H P
Sbjct: 53 LLIKDGIILAIEPQ---SSCQIPATETLDLGQQVLMPGWVNAHGHAAMSLFRGLADDLPL 109
Query: 75 MG----------SRSIDDFH--QGTKAALS----GGTTMIIDFAIPQKGGSLIEAFETWR 118
M ++ +D+ QGT+ A++ GTT D S A
Sbjct: 110 MTWLQEHVWPAEAQHVDEHFVKQGTELAIAEMIQSGTTTFADMYF-YPQQSGEAALA--- 165
Query: 119 SWADPKVCCDYSLHVAVTWWSDQ-----VKEEMK-------ILVQDKGVNSFKMFMAYKD 166
A + C ++ + Q +++ ++ + ++G+ ++
Sbjct: 166 --AGIRAVC-FAPVLDFPTNYAQNADEYIRKAIECNDRFNNHPMNEQGLV--QIGFGPHA 220
Query: 167 LYMVTDLELYEAFSRCKEIGAIAQVH 192
Y V+D L E ++ Q+H
Sbjct: 221 PYTVSDEPLKEITMLSDQLDMPVQIH 246
>4DZH-A nrPDB
Length = 472
Score = 40.5 bits (93), Expect = 0.002, Method: Composition-based stats.
Identities = 79/450 (17%), Positives = 131/450 (29%), Gaps = 109/450 (24%)
Query: 3 APSRLLIRGGRVV----NDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKL 58
P LLI G VV + E V V +GV+ A+ A R +
Sbjct: 12 EPCDLLIEAGYVVPIEPHAVVLEDHAVAVSNGVIVAVLP-TADARVRFAPARTVSRPDAA 70
Query: 59 VLPGGIDTHTHMQFPFMGSRSID--------DFHQGTKAALSG------GTTMIIDFAIP 104
++PG ++ HTH + + D +AA+ G GTT+ I
Sbjct: 71 LMPGLVNAHTHNPMTLLRGVADDLPLMVWLQQHIWPVEAAVIGPEFVADGTTLAIA---- 126
Query: 105 QKGGSLIEAFETWRSWADPKVCCDYSLHVAVTWWSDQVKEEMKILVQDKGVNSF--KMFM 162
E R C + + A + + + G + + +
Sbjct: 127 ----------EMLR---GGTTCVNENYFFA---------DVQAAVYKQHGFRALVGAVII 164
Query: 163 AYKDLYMVTDLELYEAFSRCKEIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRP 222
+ + +D E + A G+L + L P P
Sbjct: 165 DFPTAWASSDDEYF----------------ARAGELHDQWRDDPLISTAFAPHA-----P 203
Query: 223 EAVEAEATLRAITIASAVNCPLYI-VHVMSKSAAKVIADARRDGK---VVYGEPIAASLG 278
V R +A ++ P+++ H ++ A +A + G +
Sbjct: 204 YTVNDANFERVRMLADQLDMPVHLHTHETAQEVADSVAQYGQRPLARLDRLGLVNDRLIA 263
Query: 279 TDGTHYWNKEWHHAAHHVMGPPLRPDPSTPDFLMNLLANDDLTTTGTDNCTFNTCQKALG 338
T E H A + P+ + + C Q+A
Sbjct: 264 VHMTQLTEAEIHLCAERGVSVVHCPESNLK--------------LASGFCPACALQRAS- 308
Query: 339 KDDFTKIPNGVNGV----------EDRMSVIWEKGVHSGKMDENRFVAVTSTNAAKI--- 385
+ G +G E+R + I K V + D A T+ AA +
Sbjct: 309 ----VNLAIGTDGCASNNDLDMFSENRTAAILAKAVAN---DATALDAATTLRAATLGGA 361
Query: 386 --FNLYPRKGRIAVGSDADIVIWDPKGTRT 413
R G I VG AD+V D T
Sbjct: 362 RALGFGDRIGSIEVGKQADLVCVDLSALET 391
>6CTY-A nrPDB
Length = 372
Score = 40.5 bits (93), Expect = 0.002, Method: Composition-based stats.
Identities = 44/284 (15%), Positives = 89/284 (31%), Gaps = 49/284 (17%)
Query: 65 DTHTHMQFPFMGSR----SIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSW 120
D H H++ M S + + F + I + + + + +R
Sbjct: 39 DWHIHLRDDEMLSTVLPYTSEVFARA------------IVMPNLAQPITTVASAIAYRER 86
Query: 121 ADPKVCCDYSLHVAVTWWSDQVKEEMKILVQ-DKGV-NSFKMF---MAYKDLYMVTDL-E 174
V + +T + + ++ ++GV + K++ + V+D+
Sbjct: 87 ILAAVPAGHKFTPLMTCYLTNSLDAKELTTGFEQGVFTAAKLYPANATTNSTHGVSDIPA 146
Query: 175 LYEAFSRCKEIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAI 234
+Y F + ++IG +H G++ + E R + E +
Sbjct: 147 IYPLFEQMQKIGMPLLIH---GEVTDAAVDIFDREARFIDQILEPIRQKFPELKIVFE-- 201
Query: 235 TIASAVNCPLYIVHVMSKSAAK-VIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAA 293
H+ +K AA V+A R G V L + H
Sbjct: 202 -------------HITTKDAADYVLAGNRFLGATVT----PQHLMFNRNHML---VGGIR 241
Query: 294 HHVMGPPLRPDPSTPDFLMNLLAND-DLTTTGTDNCTFNTCQKA 336
H+ P+ + L +A+ D GTD+ +K
Sbjct: 242 PHLFCLPILKRSTHQQALRAAVASGSDRFFLGTDSAPHAKHRKE 285
>3JZE-A nrPDB
Length = 372
Score = 40.1 bits (92), Expect = 0.003, Method: Composition-based stats.
Identities = 39/286 (13%), Positives = 84/286 (29%), Gaps = 51/286 (17%)
Query: 65 DTHTHMQFPFMGSRSID-DFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWADP 123
D H H++ M + +A I + ++A +R
Sbjct: 39 DWHVHLRDGDMLKTVVPYTSEIYGRA---------IVMPNLASPITTVDAAIAYRQRILD 89
Query: 124 KVCCDYSLHVAVT-WWSDQVK-EEMKILVQDKGVNSFKMFMAYKDL----YMVTDLELYE 177
V + +T + +D + +E++ + + K++ A + + +
Sbjct: 90 AVPAGHDFTPLMTCYLTDSLDADELERGFHEGVFTAAKLYPANATTNSSHGVTSVDAIMP 149
Query: 178 AFSRCKEIGAIAQVHAE----NGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRA 233
R +++G VH E + D+ A+ + + P
Sbjct: 150 VLERMEKLGIPLLVHGEVTHADVDIFDREARFI----------DTVMEP----------- 188
Query: 234 ITIASAVNCPLYIVHVMSKSAAKVIADARRDGKVVYGEPI-AASLGTDGTHYWNKEWHHA 292
+ H+ +K AA+ + D G I L + +
Sbjct: 189 -LRQRLTALKVVFEHITTKDAAQYVRD----GNDYLAATITPQHLMFNR---NDMLVGGI 240
Query: 293 AHHVMGPPLRPDPSTPDFLMNLLANDDLTT-TGTDNCTFNTCQKAL 337
H+ P+ L L+A+ GTD+ + +K
Sbjct: 241 RPHLYCLPILKRNIHQQALRELVASGFTRAFLGTDSAPHSRHRKET 286
>2OOD-A nrPDB
Length = 475
Score = 37.8 bits (86), Expect = 0.012, Method: Composition-based stats.
Identities = 14/46 (30%), Positives = 25/46 (54%), Gaps = 1/46 (2%)
Query: 25 VLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGIDTHTHM 70
++V DGV++A G P G+ + ++++PG ID H H+
Sbjct: 38 MVVTDGVIKAFGPYEKIAAAHP-GVEITHIKDRIIVPGFIDGHIHL 82
>3MDW-A nrPDB
Length = 453
Score = 36.6 bits (83), Expect = 0.027, Method: Composition-based stats.
Identities = 14/69 (20%), Positives = 25/69 (36%), Gaps = 3/69 (4%)
Query: 393 GRIAVGSDADIVIWDPKGTRTISAKTHHQAVNFNIFEGMVCHGVPLVTISRGKVVYEAGV 452
G +AVG AD+++ D SA+ + +F G + G+ V G
Sbjct: 377 GSLAVGRRADLLVLDGNDPYLASAEGDALLNRW-LFAGGDRQ--VRDVMVAGRWVVRDGR 433
Query: 453 FSVTAGDGK 461
+ +
Sbjct: 434 HAGEERSAR 442
>2I9U-A nrPDB
Length = 439
Score = 36.2 bits (82), Expect = 0.038, Method: Composition-based stats.
Identities = 11/45 (24%), Positives = 22/45 (48%), Gaps = 3/45 (6%)
Query: 25 VLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGIDTHTH 69
++V DG + ++ +L G ++D +++PG D H H
Sbjct: 34 IVVIDGKIASVSSNL---PDKYKGNPIIDFRNNIIIPGMNDLHAH 75
>2PAJ-A nrPDB
Length = 492
Score = 35.8 bits (81), Expect = 0.051, Method: Composition-based stats.
Identities = 16/78 (20%), Positives = 28/78 (35%), Gaps = 4/78 (5%)
Query: 7 LLIRGGRVVNDDFSEVAD--VLVEDGVVRALGHDLLPPGG--APAGLRVLDAAGKLVLPG 62
LIR + AD V +R +G + G G ++DA ++ P
Sbjct: 12 TLIRNAAAIMTGGRGTADDPSRVPGPDIRIVGDTIDAIGALAPRPGETIVDATDCVIYPA 71
Query: 63 GIDTHTHMQFPFMGSRSI 80
++TH H+ +
Sbjct: 72 WVNTHHHLFQSLLKGEPA 89
>2WJF-A nrPDB
Length = 247
Score = 35.4 bits (80), Expect = 0.066, Method: Composition-based stats.
Identities = 27/158 (17%), Positives = 55/158 (34%), Gaps = 14/158 (8%)
Query: 62 GGIDTHTHMQ-FPFMGSRSIDDFHQGTKAALSGGTTMIIDFA------IPQKGGSLIEAF 114
G ID H+H+ G +S ++ + G I+ + + E F
Sbjct: 4 GMIDIHSHIVFDVDDGPKSREESKALLAESYRQGVRTIVSTSHRRKGMFETPEEKIAENF 63
Query: 115 ETWRSWADPKVCCDYSLHVAVTWWSDQVKEEMKILVQDKGVNSF-KMFMAYKDLYMVTDL 173
R A + A +++ V ++++ K + + A + M T
Sbjct: 64 LQVREIAKEVASDLVIAYGAEIYYTPDVLDKLE----KKRIPTLNDSRYALIEFSMNTPY 119
Query: 174 -ELYEAFSRCKEIG-AIAQVHAENGDLIAEGAKKMLAL 209
+++ A S+ +G H E D + K++ L
Sbjct: 120 RDIHSALSKILMLGITPVIAHIERYDALENNEKRVREL 157
>6FV3-A nrPDB
Length = 401
Score = 33.9 bits (76), Expect = 0.20, Method: Composition-based stats.
Identities = 25/136 (18%), Positives = 43/136 (31%), Gaps = 12/136 (8%)
Query: 5 SRLLIRGGRVVNDDFS-EVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGG 63
S +L+ V+ + + V A+G P V+PG
Sbjct: 15 SHMLLTADTVLTGTELLRPGWLEIASDRVVAVGAGAPPAQADRNL------GAATVVPGF 68
Query: 64 IDTHTHMQFPFMGSRSIDDFHQGTKAAL--SGGTTMIIDFAIPQKGGSLIEAFETWRSWA 121
+DTH H S + DD AL + G+T ++ + L+
Sbjct: 69 VDTHLHGGGGGNFSAATDD-ETARAVALHRAHGSTTLVASLVTAGPEDLLRQVSGLARQV 127
Query: 122 DPKVCCDYSLHVAVTW 137
+ D +H+ W
Sbjct: 128 RAGL-ID-GIHLEGPW 141
>5YDJ-A nrPDB
Length = 737
Score = 32.7 bits (73), Expect = 0.37, Method: Composition-based stats.
Identities = 20/80 (25%), Positives = 29/80 (36%), Gaps = 10/80 (12%)
Query: 189 AQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAVNCPLYIVH 248
+H + + +L G + R EATLRA+ +A AV CP H
Sbjct: 366 VSLHLLSALSRDLFQRAILQSGSPTAPWALVSR-----EEATLRALRLAEAVGCP----H 416
Query: 249 VMSKSAAKVIADARRDGKVV 268
SK + + R V
Sbjct: 417 EPSKLS-DAVECLRGKDPHV 435
>5YDI-A nrPDB
Length = 553
Score = 32.7 bits (73), Expect = 0.37, Method: Composition-based stats.
Identities = 20/80 (25%), Positives = 29/80 (36%), Gaps = 10/80 (12%)
Query: 189 AQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAVNCPLYIVH 248
+H + + +L G + R EATLRA+ +A AV CP H
Sbjct: 205 VSLHLLSALSRDLFQRAILQSGSPTAPWALVSR-----EEATLRALRLAEAVGCP----H 255
Query: 249 VMSKSAAKVIADARRDGKVV 268
SK + + R V
Sbjct: 256 EPSKLS-DAVECLRGKDPHV 274
>6NRZ-A nrPDB
Length = 534
Score = 32.7 bits (73), Expect = 0.39, Method: Composition-based stats.
Identities = 25/134 (18%), Positives = 47/134 (35%), Gaps = 14/134 (10%)
Query: 105 QKGGSLIEAFETWRSWADPKVCCDYSL-HVAVTWWSDQVKEEMKILVQDKGVNSFKM--- 160
++IEA+ + + D C + + ++ + + + + L V FK
Sbjct: 288 NPEFTMIEAYAAYWDYNDVMKCVENLVEYIVRALNNGETQVQYSHLKSGPQVVDFKAPWI 347
Query: 161 FMAYK---------DLYMVTDLELYEAFSRCKEIGAIAQVHAENGDLIAEGAKKMLALGI 211
M K D+ + D EL + + VHA G+LIA +++ +
Sbjct: 348 RMTMKESISVYGGVDVDLHADHELRKILETQTSLPEKTYVHASRGELIALLFDELVCDKL 407
Query: 212 TGPEGHELCRPEAV 225
P H P
Sbjct: 408 IAPH-HITDHPLET 420
>5JCN-A nrPDB
Length = 451
Score = 32.4 bits (72), Expect = 0.47, Method: Composition-based stats.
Identities = 22/107 (20%), Positives = 35/107 (32%), Gaps = 21/107 (19%)
Query: 392 KGRIAVGSDAD----IVIWDPKGTRTISAKTHHQAVNFNIFEGMVCHGVPLVTISRGKVV 447
KG +AVG DAD + + K + A G PL T+ +G+V
Sbjct: 241 KGTVAVGFDADANGDVTAVNLKNGSVLEADIVVVG----------VGGRPLTTLFKGQVA 290
Query: 448 YEAGVFSVTAGDGKFIP-------RKPFAEYIYKRIKQRDRTCTPTP 487
E G A +P F +Y +++ +
Sbjct: 291 EEKGGIKTDAFFETSVPGVYAVGDVATFPMKMYNELRRVEHVDHARK 337
>1S69-A nrPDB
Length = 124
Score = 32.0 bits (71), Expect = 0.58, Method: Composition-based stats.
Identities = 18/88 (20%), Positives = 35/88 (39%), Gaps = 1/88 (1%)
Query: 114 FETWRSWADPKVCCDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDL 173
+ + A K Y+ + ++E K LV++ G+N F A + + T
Sbjct: 38 VDMAKQRAHQKAFLTYAFGGTDKYDGRYMREAHKELVENHGLNGE-HFDAVAEDLLATLK 96
Query: 174 ELYEAFSRCKEIGAIAQVHAENGDLIAE 201
E+ E+ A+A A D++ +
Sbjct: 97 EMGVPEDLIAEVAAVAGAPAHKRDVLNQ 124
>2QIW-A nrPDB
Length = 255
Score = 31.6 bits (70), Expect = 0.86, Method: Composition-based stats.
Identities = 22/151 (14%), Positives = 44/151 (29%), Gaps = 22/151 (14%)
Query: 146 MKILVQDKGVNSFKMFMAYKDLYMVTDLELYEAFSRCKEIGAIA--QVHAENGDLIAEGA 203
M ++ + S + + + Y ++ +L +G VH+E G + E
Sbjct: 69 MAVVKKITSAVSIPVSVDVESGYGLSPADLIAQILEAGAVGINVEDVVHSE-GKRVREAQ 127
Query: 204 KKM-----------------LALGITGPEGHELCRPEAVEAEATLRAITIASAVNCP-LY 245
+ + G T E EA R I + +Y
Sbjct: 128 EHADYIAAARQAADVAGVDVVINGRTDAVKLGADVFEDPMVEAIKR-IKLMEQAGARSVY 186
Query: 246 IVHVMSKSAAKVIADARRDGKVVYGEPIAAS 276
V + + + + DA + P+
Sbjct: 187 PVGLSTAEQVERLVDAVSVPVNITAHPVDGH 217
>3RZZ-A nrPDB
Length = 446
Score = 30.8 bits (68), Expect = 1.5, Method: Composition-based stats.
Identities = 31/147 (21%), Positives = 45/147 (30%), Gaps = 21/147 (14%)
Query: 84 HQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWADPKVC--------CDYSLHVAV 135
H T AA + G L A + S V DY + +
Sbjct: 247 HTRTSAAEAAGV----------PPADLEAALRSPASETGLTVLRTLGRALGFDYRVLLPA 296
Query: 136 TWWSDQVKEEMKILVQ-DKGVNSFKMFMAYKDLYMVTDLELYEAFSR--CKEIGAIAQVH 192
D V + + + +F + A +L +F R GA H
Sbjct: 297 DDQHDGVGKTWTTIEDSRRSRRTFGTYEAASMASAAHLPDLVGSFLRVDADGRGADLIDH 356
Query: 193 AENGDLIAEGAKKMLALGITGPEGHEL 219
AEN ++ EG + G GP EL
Sbjct: 357 AENHYVVTEGRLTLEWDGPDGPASVEL 383
>6ERI-Ad nrPDB
Length = 72
Score = 30.1 bits (66), Expect = 2.2, Method: Composition-based stats.
Identities = 11/45 (24%), Positives = 22/45 (48%), Gaps = 2/45 (4%)
Query: 458 GDGKFIPRKPFAEYIY--KRIKQRDRTCTPTPVERAPYKGEVATL 500
G GK + R+ +++ K K+++R V+R+ Y + L
Sbjct: 19 GKGKIVRRRAGKQHLLAKKNTKRKNRLSKLIQVDRSDYDNVIGAL 63
>5MLC-5 nrPDB
Length = 159
Score = 30.1 bits (66), Expect = 2.2, Method: Composition-based stats.
Identities = 11/45 (24%), Positives = 22/45 (48%), Gaps = 2/45 (4%)
Query: 458 GDGKFIPRKPFAEYIY--KRIKQRDRTCTPTPVERAPYKGEVATL 500
G GK + R+ +++ K K+++R V+R+ Y + L
Sbjct: 106 GKGKIVRRRAGKQHLLAKKNTKRKNRLSKLIQVDRSDYDNVIGAL 150
>1Z72-A nrPDB
Length = 225
Score = 30.1 bits (66), Expect = 2.8, Method: Composition-based stats.
Identities = 25/145 (17%), Positives = 50/145 (34%), Gaps = 10/145 (6%)
Query: 105 QKGGSLIEAFETWRSWADPKVCCDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAY 164
Q G ++ E S D + ++ + + + K L+QD F F++
Sbjct: 12 QPGLTVGE--LLKSSQKDWQAAINHRFVKELFAGTIENKVLKDYLIQDYHF--FDAFLSM 67
Query: 165 KDLYMVTDLELYEAFSRCKEIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEA 224
+ +L K++G + E+G K L + + E+
Sbjct: 68 LGACVAHADKLESKLRFAKQLGFLEAD--EDG----YFQKAFKELKVAENDYLEVTLHPV 121
Query: 225 VEAEATLRAITIASAVNCPLYIVHV 249
+A L +AS+ L ++ V
Sbjct: 122 TKAFQDLMYSAVASSDYAHLLVMLV 146
>2QI2-A nrPDB
Length = 347
Score = 29.7 bits (65), Expect = 3.4, Method: Composition-based stats.
Identities = 13/62 (20%), Positives = 23/62 (37%)
Query: 193 AENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAVNCPLYIVHVMSK 252
A D+ G + + G + E E R+++IA V ++IV V +
Sbjct: 260 AVKKDMGVYGRDQTESALQMGALSDLIITDEMFRTEDGRRSLSIAQTVGTRIHIVSVSND 319
Query: 253 SA 254
Sbjct: 320 PG 321
>4WVX-A nrPDB
Length = 326
Score = 29.7 bits (65), Expect = 3.4, Method: Composition-based stats.
Identities = 18/88 (20%), Positives = 33/88 (37%), Gaps = 15/88 (17%)
Query: 145 EMKILVQDKGVNSFKMFMAYKDLYMVTDLELY--EAFSRCKEIGAIAQVHAENGDLIAEG 202
E+ + D G+ + + +A + +++ A KE GA+ H + G + E
Sbjct: 129 ELTEGIADTGIKAGVIKLASSKGRITEYEKMFFRAAARAQKETGAVIITHTQEGTMGPEQ 188
Query: 203 AKKMLAL-------------GITGPEGH 217
A +L G T P+ H
Sbjct: 189 AAYLLEHGADPKKIVIGHMCGNTDPDYH 216
>2OI8-A nrPDB
Length = 216
Score = 29.7 bits (65), Expect = 3.5, Method: Composition-based stats.
Identities = 20/77 (25%), Positives = 30/77 (38%), Gaps = 13/77 (16%)
Query: 70 MQFPFMGSRSIDDFHQGTKAALSGGTTM--IIDFAIPQKGGSLIE-----AFETWRSWAD 122
P G R+ DD T+ A TM I+D + +T R WA
Sbjct: 111 FGTPVPGYRAPDDI---TEIAAE---TMAVIVDACAALPPSDGTDGAFDAHLDTHRQWAG 164
Query: 123 PKVCCDYSLHVAVTWWS 139
+ +LH A+++WS
Sbjct: 165 DRPAPSSALHRALSFWS 181
>2YFK-A nrPDB
Length = 418
Score = 29.3 bits (64), Expect = 4.7, Method: Composition-based stats.
Identities = 22/121 (18%), Positives = 35/121 (28%), Gaps = 17/121 (14%)
Query: 345 IPNGVNGVEDRMSVIWEKGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVG-SDADI 403
+P G+ G+ R+ + G V NAA+ + + +A DAD+
Sbjct: 207 VPQGIVGLMTRLGMDVVLAHPEGYEIMPEVEEVAKKNAAEFGGNFTKTNSMAEAFKDADV 266
Query: 404 VI---WDPKGTRT-------------ISAKTHHQAVNFNIFEGMVCHGVPLVTISRGKVV 447
V W P I + C + T GK +
Sbjct: 267 VYPKSWAPFAAMEKRTELYGNGDQAGIDQLEQELLSQNKKHKDWECTEELMKTTKDGKAL 326
Query: 448 Y 448
Y
Sbjct: 327 Y 327
>5WLC-LV nrPDB
Length = 707
Score = 28.9 bits (63), Expect = 5.1, Method: Composition-based stats.
Identities = 13/72 (18%), Positives = 29/72 (40%), Gaps = 4/72 (5%)
Query: 359 IWEKGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIV-IWDPKGTRTISAK 417
++ + G+ N F T ++ G +A G++ ++V WDP+ +S
Sbjct: 162 LYRLNLEKGRF-LNPF--KLDTEGVNHVSINEVNGLLAAGTETNVVEFWDPRSRSRVSKL 218
Query: 418 THHQAVNFNIFE 429
++ F+
Sbjct: 219 YLENNIDNRPFQ 230
>1AOS-A nrPDB
Length = 464
Score = 28.5 bits (62), Expect = 8.2, Method: Composition-based stats.
Identities = 28/139 (20%), Positives = 49/139 (35%), Gaps = 10/139 (7%)
Query: 110 LIEAFETWRSWADPKVCCDYSLHVAVTWWSDQVKEEMKILVQDKGVNSF--KMFMAYKDL 167
L +A+ T S K D SL + + +L+ KG+ S K K+
Sbjct: 273 LSDAYSTGSSLMPQKKNPD-SLELIRSKAGRVFGRCAGLLMTLKGLPSTYNKDLQEDKEA 331
Query: 168 YMVTDLELYEAFSRCKEIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCR--PEAV 225
+ + + Q+H EN + + MLA T + + + P
Sbjct: 332 VFEVSDTMSAVLQVATGVISTLQIHQEN--MGQALSPDMLA---TDLAYYLVRKGMPFRQ 386
Query: 226 EAEATLRAITIASAVNCPL 244
EA+ +A+ +A L
Sbjct: 387 AHEASGKAVFMAETKGVAL 405
Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta
Posted date: Jan 3, 2023 9:05 PM
Number of letters in database: 10,336,785
Number of sequences in database: 36,641
Lambda K H
0.306 0.132 0.347
Lambda K H
0.267 0.0408 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,462,366
Number of Sequences: 36641
Number of extensions: 796357
Number of successful extensions: 2664
Number of sequences better than 10.0: 101
Number of HSP's better than 10.0 without gapping: 124
Number of HSP's successfully gapped in prelim test: 50
Number of HSP's that attempted gapping in prelim test: 2242
Number of HSP's gapped (non-prelim): 240
length of query: 519
length of database: 10,336,785
effective HSP length: 101
effective length of query: 418
effective length of database: 6,636,044
effective search space: 2773866392
effective search space used: 2773866392
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.0 bits)
S2: 61 (28.1 bits)