BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q13868 (293 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 6D6R-H nrPDB 600 e-172 4OO1-H nrPDB 218 3e-57 5JEA-H nrPDB 217 4e-57 2BA0-A nrPDB 62 2e-10 2JEB-I nrPDB 46 2e-05 2Z0S-A nrPDB 44 8e-05 5OKZ-G nrPDB 40 0.001 2JA9-A nrPDB 38 0.005 1ZWS-A nrPDB 32 0.29 3DL9-A nrPDB 28 3.2 6D6Q-G nrPDB 28 4.7 3M7N-A nrPDB 28 5.5 4WSI-A nrPDB 27 9.3 >6D6R-H nrPDB Length = 296 Score = 600 bits (1548), Expect = e-172, Method: Compositional matrix adjust. Identities = 293/293 (100%), Positives = 293/293 (100%) Query: 1 MAMEMRLPVARKPLSERLGRDTKKHLVVPGDTITTDTGFMRGHGTYMGEEKLIASVAGSV 60 MAMEMRLPVARKPLSERLGRDTKKHLVVPGDTITTDTGFMRGHGTYMGEEKLIASVAGSV Sbjct: 4 MAMEMRLPVARKPLSERLGRDTKKHLVVPGDTITTDTGFMRGHGTYMGEEKLIASVAGSV 63 Query: 61 ERVNKLICVKALKTRYIGEVGDIVVGRITEVQQKRWKVETNSRLDSVLLLSSMNLPGGEL 120 ERVNKLICVKALKTRYIGEVGDIVVGRITEVQQKRWKVETNSRLDSVLLLSSMNLPGGEL Sbjct: 64 ERVNKLICVKALKTRYIGEVGDIVVGRITEVQQKRWKVETNSRLDSVLLLSSMNLPGGEL 123 Query: 121 RRRSAEDELAMRGFLQEGDLISAEVQAVFSDGAVSLHTRSLKYGKLGQGVLVQVSPSLVK 180 RRRSAEDELAMRGFLQEGDLISAEVQAVFSDGAVSLHTRSLKYGKLGQGVLVQVSPSLVK Sbjct: 124 RRRSAEDELAMRGFLQEGDLISAEVQAVFSDGAVSLHTRSLKYGKLGQGVLVQVSPSLVK 183 Query: 181 RQKTHFHDLPCGASVILGNNGFIWIYPTPEHKEEEAGGFIANLEPVSLADREVISRLRNC 240 RQKTHFHDLPCGASVILGNNGFIWIYPTPEHKEEEAGGFIANLEPVSLADREVISRLRNC Sbjct: 184 RQKTHFHDLPCGASVILGNNGFIWIYPTPEHKEEEAGGFIANLEPVSLADREVISRLRNC 243 Query: 241 IISLVTQRMMLYDTSILYCYEASLPHQIKDILKPEIMEEIVMETRQRLLEQEG 293 IISLVTQRMMLYDTSILYCYEASLPHQIKDILKPEIMEEIVMETRQRLLEQEG Sbjct: 244 IISLVTQRMMLYDTSILYCYEASLPHQIKDILKPEIMEEIVMETRQRLLEQEG 296 >4OO1-H nrPDB Length = 363 Score = 218 bits (555), Expect = 3e-57, Method: Compositional matrix adjust. Identities = 123/296 (41%), Positives = 169/296 (57%), Gaps = 36/296 (12%) Query: 21 DTKKHLVVPGDTITTDTGFMRGHGTYMGEEKLIASVAGSVERVNKLICVKALKTRYIGEV 80 ++ +V PG+ +T D +MRGHGTY + +SVAG+V RVN+L+ V LK RY E Sbjct: 53 ESDSQIVTPGELVTDDPIWMRGHGTYFLDNMTYSSVAGTVSRVNRLLSVIPLKGRYAPET 112 Query: 81 GDIVVGRITEVQQKRWKVETNSRLDSVLLLSSMNLPGGELRRRSAEDELAMRGFLQEGDL 140 GD VVGRI EV KRWKV+ + +VL+L S+NLPGG LRR+S DEL MR FL+EGDL Sbjct: 113 GDHVVGRIAEVGNKRWKVDIGGKQHAVLMLGSVNLPGGILRRKSESDELQMRSFLKEGDL 172 Query: 141 ISAEVQAVFSDGAVSLHTRSLKYGKLGQGVLVQVSPSLVKRQKTHFHDLPCGASVILGNN 200 ++AEVQ++F DG+ SLHTRSLKYGKL G+ QV SL+ R K H H+LP +V+LG N Sbjct: 173 LNAEVQSLFQDGSASLHTRSLKYGKLRNGMFCQVPSSLIVRAKNHTHNLPGNITVVLGVN 232 Query: 201 GFIWIYPTPEHK--------------------------------EEEAGGFI---ANLEP 225 G+IW+ T + EEE+ I N Sbjct: 233 GYIWLRKTSQMDLARDTPSANNSSSIKSTGPTGAVSLNPSITRLEEESSWQIYSDENDPS 292 Query: 226 VSLADREVISRLRNCIISLVTQRMMLYDTSILYCYEASLPH-QIKDILKPEIMEEI 280 +S R+ I R N I +L + + I+ YEAS+ + + ++++ +ME I Sbjct: 293 ISNNIRQAICRYANVIKALAFCEIGITQQRIVSAYEASMVYSNVGELIEKNVMESI 348 >5JEA-H nrPDB Length = 316 Score = 217 bits (553), Expect = 4e-57, Method: Compositional matrix adjust. Identities = 123/295 (41%), Positives = 168/295 (56%), Gaps = 36/295 (12%) Query: 22 TKKHLVVPGDTITTDTGFMRGHGTYMGEEKLIASVAGSVERVNKLICVKALKTRYIGEVG 81 + +V PG+ +T D +MRGHGTY + +SVAG+V RVN+L+ V LK RY E G Sbjct: 7 SDSQIVTPGELVTDDPIWMRGHGTYFLDNMTYSSVAGTVSRVNRLLSVIPLKGRYAPETG 66 Query: 82 DIVVGRITEVQQKRWKVETNSRLDSVLLLSSMNLPGGELRRRSAEDELAMRGFLQEGDLI 141 D VVGRI EV KRWKV+ + +VL+L S+NLPGG LRR+S DEL MR FL+EGDL+ Sbjct: 67 DHVVGRIAEVGNKRWKVDIGGKQHAVLMLGSVNLPGGILRRKSESDELQMRSFLKEGDLL 126 Query: 142 SAEVQAVFSDGAVSLHTRSLKYGKLGQGVLVQVSPSLVKRQKTHFHDLPCGASVILGNNG 201 +AEVQ++F DG+ SLHTRSLKYGKL G+ QV SL+ R K H H+LP +V+LG NG Sbjct: 127 NAEVQSLFQDGSASLHTRSLKYGKLRNGMFCQVPSSLIVRAKNHTHNLPGNITVVLGVNG 186 Query: 202 FIW--------------------------------IYPTPEHKEEEAGGFI---ANLEPV 226 +IW + P+ EEE+ I N + Sbjct: 187 YIWLRKTSQMDLARDTPSANNSSSIKSTGPTGAVSLNPSITRLEEESSWQIYSDENDPSI 246 Query: 227 SLADREVISRLRNCIISLVTQRMMLYDTSILYCYEASLPH-QIKDILKPEIMEEI 280 S R+ I R N I +L + + I+ YEAS+ + + ++++ +ME I Sbjct: 247 SNNIRQAICRYANVIKALAFCEIGITQQRIVSAYEASMVYSNVGELIEKNVMESI 301 >2BA0-A nrPDB Length = 229 Score = 62.4 bits (150), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 52/188 (27%), Positives = 88/188 (46%), Gaps = 16/188 (8%) Query: 24 KHLVVPGDTITTDTGFMRGHGTYMGEEKLIASVAGSVERVNKLICVKALKTRYIGEVGDI 83 + +V+PGD ++T+ G+GTY+ K+ A + G ++ + V LK RY VGD+ Sbjct: 2 RKIVLPGDLLSTNP-RAAGYGTYVEGGKVYAKIIGLFDQTETHVRVIPLKGRYTPSVGDV 60 Query: 84 VVGRITEVQQKRWKVETNSRLDSVLLLSSMNLPGGELRRRSAEDELAMRGFLQEGDLISA 143 V+G I EV W V+ S + L +S E++ +E+ L GD I A Sbjct: 61 VIGIIREVAANGWAVDIYSPYQAFLPVSE----NPEMKPNKKPNEV-----LDIGDAIIA 111 Query: 144 EVQAVFSDGAVSLHTRSLKYGKLGQGVLVQVSPSLVKR---QKTHFHDL---PCGASVIL 197 +V + V+L + + G +V ++P+ V R +K L +++ Sbjct: 112 KVLNIDPKMKVTLTMKDRICRPIRFGRIVAINPARVPRVIGKKGSMIKLLKSELDVQIVV 171 Query: 198 GNNGFIWI 205 G NG IW+ Sbjct: 172 GQNGLIWV 179 >2JEB-I nrPDB Length = 251 Score = 45.8 bits (107), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 33/135 (24%), Positives = 58/135 (42%), Gaps = 13/135 (9%) Query: 76 YIGEVGDIVVGRITEVQQKRWKVETNSRLDSVLLLSSMNLPGGELRRRSAEDELAMRGFL 135 Y ++ DIV+G + +V+ W V+ + + LP L RS +R +L Sbjct: 70 YYPKINDIVIGLVEDVEIYGWVVDIKAPYKAY-------LPASNLLGRSINVGEDLRRYL 122 Query: 136 QEGDLISAEVQAVFSDGAVSLHTRSLKYGKLGQGVLVQVSPSLVKR----QKTHFHDL-- 189 GD + A ++ L + G++ G+++ + P V R K+ + L Sbjct: 123 DVGDYVIARIENFDRSIDPVLSVKGKDLGRVSNGIVIDIMPVKVPRVIGKNKSMYETLTS 182 Query: 190 PCGASVILGNNGFIW 204 G S+ + NNG IW Sbjct: 183 KSGCSIFVANNGRIW 197 >2Z0S-A nrPDB Length = 235 Score = 43.9 bits (102), Expect = 8e-05, Method: Compositional matrix adjust. Identities = 35/110 (31%), Positives = 55/110 (50%), Gaps = 6/110 (5%) Query: 72 LKTRYIGEVGDIVVGRITEVQQKRWKVETNSRLDSVLLLSSMNLPGGELRRRSAEDELAM 131 LK Y+ + GD+V+G I V W V+ NS V +LS + G A D+ M Sbjct: 58 LKEIYVPQAGDVVIGLIQSVGIMNWFVDINS--PYVAVLSVQDFLGRPF--NPAVDD--M 111 Query: 132 RGFLQEGDLISAEVQAVFSDGAVSLHTRSLKYGKLGQGVLVQVSPSLVKR 181 + L+ GD I A+V A + L + G++ +G +V++SP+ V R Sbjct: 112 QSLLKVGDYIKAKVVAFDKTRSPLLTVQGEGLGRIVRGKIVEISPAKVPR 161 >5OKZ-G nrPDB Length = 244 Score = 40.4 bits (93), Expect = 0.001, Method: Compositional matrix adjust. Identities = 52/211 (24%), Positives = 76/211 (36%), Gaps = 35/211 (16%) Query: 19 GRDTKKHLVVPGDTITTD--TGFMRGHGTYMG-EEKLIASVAGSVERVN-------KLIC 68 G D+ + PGD+ D T G G Y + I V V V+ + Sbjct: 1 GPDSMSTFIFPGDSFPVDPTTPVKLGPGIYCDPNTQEIRPVNTGVLHVSAKGKSGVQTAY 60 Query: 69 VKALKTRYIGEVGDIVVGRITEVQQKRWKVETNSRLDSVLLLSSMNLPGGELRRRSAEDE 128 + RYI V D V+G I +KV + S + LS M P + R Sbjct: 61 IDYSSKRYIPSVNDFVIGVIIGTFSDSYKVSLQN-FSSSVSLSYMAFPNASKKNRPT--- 116 Query: 129 LAMRGFLQEGDLISAEVQAVFSDGAVSLHT------RSLKYGKLGQGVLVQVSPSLVKRQ 182 LQ GDL+ A V + + R +G L G+++ V+ + RQ Sbjct: 117 ------LQVGDLVYARVCTAEKELEAEIECFDSTTGRDAGFGILEDGMIIDVNLNFA-RQ 169 Query: 183 KTHFHDLP--------CGASVILGNNGFIWI 205 +D P V +G NG IW+ Sbjct: 170 LLFNNDFPLLKVLAAHTKFEVAIGLNGKIWV 200 >2JA9-A nrPDB Length = 175 Score = 38.1 bits (87), Expect = 0.005, Method: Compositional matrix adjust. Identities = 38/145 (26%), Positives = 55/145 (37%), Gaps = 25/145 (17%) Query: 75 RYIGEVGDIVVGRITEVQQKRWKVETNSRLDSVLLLSSMNLPGGELRRRSAEDELAMRGF 134 RYI V D V+G I +KV + S + LS M P + R Sbjct: 2 RYIPSVNDFVIGVIIGTFSDSYKVSLQN-FSSSVSLSYMAFPNASKKNRPT--------- 51 Query: 135 LQEGDLISAEVQAVFSDGAVSLHT------RSLKYGKLGQGVLVQVSPSLVKRQKTHFHD 188 LQ GDL+ A V + + R +G L G+++ V+ + RQ +D Sbjct: 52 LQVGDLVYARVCTAEKELEAEIECFDSTTGRDAGFGILEDGMIIDVNLNFA-RQLLFNND 110 Query: 189 LP--------CGASVILGNNGFIWI 205 P V +G NG IW+ Sbjct: 111 FPLLKVLAAHTKFEVAIGLNGKIWV 135 >1ZWS-A nrPDB Length = 288 Score = 32.0 bits (71), Expect = 0.29, Method: Compositional matrix adjust. Identities = 55/201 (27%), Positives = 86/201 (42%), Gaps = 25/201 (12%) Query: 102 SRLDSVLLLSSMNLPGGELRRRSAEDELAMRGFLQEGDLISAEVQAVFSDGAVSLHTRSL 161 +R D VL+L ++ GGEL D LA + L E + S Q + DG LHT+ + Sbjct: 86 NRTDVVLILELVS--GGELF-----DFLAQKESLSEEEATSFIKQIL--DGVNYLHTKKI 136 Query: 162 KYGKLGQGVLVQVSPSLVKRQKTHFHDLPCG-ASVILGNNGFIWIYPTPEHKEEEAGGFI 220 + L ++ + ++ H + G A I F I+ TPE E I Sbjct: 137 AHFDLKPENIMLLDKNI---PIPHIKLIDFGLAHEIEDGVEFKNIFGTPEFVAPE----I 189 Query: 221 ANLEPVSL-ADREVISRLRNCIISLVT-------QRMMLYDTSILYCYEASLPHQIKDIL 272 N EP+ L AD I + ++S + Q + TS+ Y ++ ++ Sbjct: 190 VNYEPLGLEADMWSIGVITYILLSGASPFLGDTKQETLANITSVSYDFDEEFFSHTSELA 249 Query: 273 KPEIMEEIVMETRQRLLEQEG 293 K I + +V ETR+RL QE Sbjct: 250 KDFIRKLLVKETRKRLTIQEA 270 >3DL9-A nrPDB Length = 479 Score = 28.5 bits (62), Expect = 3.2, Method: Compositional matrix adjust. Identities = 27/100 (27%), Positives = 42/100 (42%), Gaps = 16/100 (16%) Query: 187 HDLPCGASVI--LGNNGF---IWIYPTPEHKEE--EAGGFIANLE---PVSLADREVISR 236 + +P G +VI L + F W P H E ++ G+ A E P SL R + Sbjct: 366 YSIPKGTTVITNLYSVHFDEKYWRDPEVFHPERFLDSSGYFAKKEALVPFSLGRRHCLGE 425 Query: 237 LRNCIISLVTQRMMLYDTSILYCYEASLPHQIKDILKPEI 276 L M L+ T++L + PH++ LKP + Sbjct: 426 ------HLARMEMFLFFTALLQRFHLHFPHELVPDLKPRL 459 >6D6Q-G nrPDB Length = 277 Score = 28.1 bits (61), Expect = 4.7, Method: Compositional matrix adjust. Identities = 36/153 (23%), Positives = 61/153 (39%), Gaps = 31/153 (20%) Query: 69 VKALKTRYIGEVGDIVVGRITEVQQKRWKVETNSRLDSVLLLSSMNLPGGELRRRSAEDE 128 V + + RY+ GD V+G +T +KV+ + LS ++ G R R Sbjct: 104 VDSQQKRYVPVKGDHVIGIVTAKSGDIFKVDVGGSEPAS--LSYLSFEGATKRNRPN--- 158 Query: 129 LAMRGFLQEGDLISAEVQAVFSDG-----AVSLHTRSLKYGKLGQ-GVLVQVSPSLVKR- 181 +Q GDLI + D + R+ G +GQ G+L +V+ L+++ Sbjct: 159 ------VQVGDLIYGQFVVANKDMEPEMVCIDSCGRANGMGVIGQDGLLFKVTLGLIRKL 212 Query: 182 ---------QKTHFHDLPCGASVILGNNGFIWI 205 + H L ++ G NG IW+ Sbjct: 213 LAPDCEIIQEVGKLHPL----EIVFGMNGRIWV 241 >3M7N-A nrPDB Length = 179 Score = 27.7 bits (60), Expect = 5.5, Method: Compositional matrix adjust. Identities = 23/81 (28%), Positives = 47/81 (58%), Gaps = 4/81 (4%) Query: 25 HLVVPGDTITTDTGFMRGHGTYMGEEKLIASVAGSVERVNKLICVKALKTRYIGEV--GD 82 V+PGD I + +++G G Y +L A+VAG + +++ V+++ I E+ GD Sbjct: 2 RFVMPGDRIGSAEEYVKGEGVYEEGGELFAAVAGKLIIKDRVAKVESISP--IPEIVKGD 59 Query: 83 IVVGRITEVQQKRWKVETNSR 103 +V+GR+ +++ +E +S+ Sbjct: 60 VVLGRVVDLRNSIALIEVSSK 80 >4WSI-A nrPDB Length = 394 Score = 26.9 bits (58), Expect = 9.3, Method: Compositional matrix adjust. Identities = 27/84 (32%), Positives = 42/84 (50%), Gaps = 12/84 (14%) Query: 215 EAGGFIANLEPVSLAD-REVISRLRNCIISLVTQRMMLYDTSIL--YCYEASLPHQ--IK 269 E G F NL S+ R+VI+ + C++SL TQ + S L Y + P Q ++ Sbjct: 266 EHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQERLR 325 Query: 270 DIL-------KPEIMEEIVMETRQ 286 +L KPE + EI+ +TR+ Sbjct: 326 ALLAKEGKNPKPEELREIIEKTRE 349 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 6D6R-H nrPDB 440 e-124 4OO1-H nrPDB 347 3e-96 5JEA-H nrPDB 345 9e-96 2BA0-A nrPDB 198 3e-51 5OKZ-G nrPDB 190 7e-49 2JEB-I nrPDB 165 2e-41 2Z0S-A nrPDB 127 6e-30 Sequences not found previously or not previously below threshold: 2JA9-A nrPDB 129 2e-30 6D6Q-G nrPDB 71 9e-13 2NN6-I nrPDB 35 0.031 1GO3-E nrPDB 33 0.13 1YZ6-A nrPDB 31 0.54 4S3P-A nrPDB 29 1.9 4OFL-A nrPDB 29 3.0 3M7N-A nrPDB 28 4.5 >6D6R-H nrPDB Length = 296 Score = 440 bits (1131), Expect = e-124, Method: Composition-based stats. Identities = 293/293 (100%), Positives = 293/293 (100%) Query: 1 MAMEMRLPVARKPLSERLGRDTKKHLVVPGDTITTDTGFMRGHGTYMGEEKLIASVAGSV 60 MAMEMRLPVARKPLSERLGRDTKKHLVVPGDTITTDTGFMRGHGTYMGEEKLIASVAGSV Sbjct: 4 MAMEMRLPVARKPLSERLGRDTKKHLVVPGDTITTDTGFMRGHGTYMGEEKLIASVAGSV 63 Query: 61 ERVNKLICVKALKTRYIGEVGDIVVGRITEVQQKRWKVETNSRLDSVLLLSSMNLPGGEL 120 ERVNKLICVKALKTRYIGEVGDIVVGRITEVQQKRWKVETNSRLDSVLLLSSMNLPGGEL Sbjct: 64 ERVNKLICVKALKTRYIGEVGDIVVGRITEVQQKRWKVETNSRLDSVLLLSSMNLPGGEL 123 Query: 121 RRRSAEDELAMRGFLQEGDLISAEVQAVFSDGAVSLHTRSLKYGKLGQGVLVQVSPSLVK 180 RRRSAEDELAMRGFLQEGDLISAEVQAVFSDGAVSLHTRSLKYGKLGQGVLVQVSPSLVK Sbjct: 124 RRRSAEDELAMRGFLQEGDLISAEVQAVFSDGAVSLHTRSLKYGKLGQGVLVQVSPSLVK 183 Query: 181 RQKTHFHDLPCGASVILGNNGFIWIYPTPEHKEEEAGGFIANLEPVSLADREVISRLRNC 240 RQKTHFHDLPCGASVILGNNGFIWIYPTPEHKEEEAGGFIANLEPVSLADREVISRLRNC Sbjct: 184 RQKTHFHDLPCGASVILGNNGFIWIYPTPEHKEEEAGGFIANLEPVSLADREVISRLRNC 243 Query: 241 IISLVTQRMMLYDTSILYCYEASLPHQIKDILKPEIMEEIVMETRQRLLEQEG 293 IISLVTQRMMLYDTSILYCYEASLPHQIKDILKPEIMEEIVMETRQRLLEQEG Sbjct: 244 IISLVTQRMMLYDTSILYCYEASLPHQIKDILKPEIMEEIVMETRQRLLEQEG 296 >4OO1-H nrPDB Length = 363 Score = 347 bits (890), Expect = 3e-96, Method: Composition-based stats. Identities = 123/296 (41%), Positives = 169/296 (57%), Gaps = 36/296 (12%) Query: 21 DTKKHLVVPGDTITTDTGFMRGHGTYMGEEKLIASVAGSVERVNKLICVKALKTRYIGEV 80 ++ +V PG+ +T D +MRGHGTY + +SVAG+V RVN+L+ V LK RY E Sbjct: 53 ESDSQIVTPGELVTDDPIWMRGHGTYFLDNMTYSSVAGTVSRVNRLLSVIPLKGRYAPET 112 Query: 81 GDIVVGRITEVQQKRWKVETNSRLDSVLLLSSMNLPGGELRRRSAEDELAMRGFLQEGDL 140 GD VVGRI EV KRWKV+ + +VL+L S+NLPGG LRR+S DEL MR FL+EGDL Sbjct: 113 GDHVVGRIAEVGNKRWKVDIGGKQHAVLMLGSVNLPGGILRRKSESDELQMRSFLKEGDL 172 Query: 141 ISAEVQAVFSDGAVSLHTRSLKYGKLGQGVLVQVSPSLVKRQKTHFHDLPCGASVILGNN 200 ++AEVQ++F DG+ SLHTRSLKYGKL G+ QV SL+ R K H H+LP +V+LG N Sbjct: 173 LNAEVQSLFQDGSASLHTRSLKYGKLRNGMFCQVPSSLIVRAKNHTHNLPGNITVVLGVN 232 Query: 201 GFIWIYPTPEHK--------------------------------EEEAGGFI---ANLEP 225 G+IW+ T + EEE+ I N Sbjct: 233 GYIWLRKTSQMDLARDTPSANNSSSIKSTGPTGAVSLNPSITRLEEESSWQIYSDENDPS 292 Query: 226 VSLADREVISRLRNCIISLVTQRMMLYDTSILYCYEASLPH-QIKDILKPEIMEEI 280 +S R+ I R N I +L + + I+ YEAS+ + + ++++ +ME I Sbjct: 293 ISNNIRQAICRYANVIKALAFCEIGITQQRIVSAYEASMVYSNVGELIEKNVMESI 348 >5JEA-H nrPDB Length = 316 Score = 345 bits (886), Expect = 9e-96, Method: Composition-based stats. Identities = 123/295 (41%), Positives = 168/295 (56%), Gaps = 36/295 (12%) Query: 22 TKKHLVVPGDTITTDTGFMRGHGTYMGEEKLIASVAGSVERVNKLICVKALKTRYIGEVG 81 + +V PG+ +T D +MRGHGTY + +SVAG+V RVN+L+ V LK RY E G Sbjct: 7 SDSQIVTPGELVTDDPIWMRGHGTYFLDNMTYSSVAGTVSRVNRLLSVIPLKGRYAPETG 66 Query: 82 DIVVGRITEVQQKRWKVETNSRLDSVLLLSSMNLPGGELRRRSAEDELAMRGFLQEGDLI 141 D VVGRI EV KRWKV+ + +VL+L S+NLPGG LRR+S DEL MR FL+EGDL+ Sbjct: 67 DHVVGRIAEVGNKRWKVDIGGKQHAVLMLGSVNLPGGILRRKSESDELQMRSFLKEGDLL 126 Query: 142 SAEVQAVFSDGAVSLHTRSLKYGKLGQGVLVQVSPSLVKRQKTHFHDLPCGASVILGNNG 201 +AEVQ++F DG+ SLHTRSLKYGKL G+ QV SL+ R K H H+LP +V+LG NG Sbjct: 127 NAEVQSLFQDGSASLHTRSLKYGKLRNGMFCQVPSSLIVRAKNHTHNLPGNITVVLGVNG 186 Query: 202 FIWIYPTPEHK--------------------------------EEEAGGFI---ANLEPV 226 +IW+ T + EEE+ I N + Sbjct: 187 YIWLRKTSQMDLARDTPSANNSSSIKSTGPTGAVSLNPSITRLEEESSWQIYSDENDPSI 246 Query: 227 SLADREVISRLRNCIISLVTQRMMLYDTSILYCYEASLPH-QIKDILKPEIMEEI 280 S R+ I R N I +L + + I+ YEAS+ + + ++++ +ME I Sbjct: 247 SNNIRQAICRYANVIKALAFCEIGITQQRIVSAYEASMVYSNVGELIEKNVMESI 301 >2BA0-A nrPDB Length = 229 Score = 198 bits (503), Expect = 3e-51, Method: Composition-based stats. Identities = 52/189 (27%), Positives = 88/189 (46%), Gaps = 16/189 (8%) Query: 23 KKHLVVPGDTITTDTGFMRGHGTYMGEEKLIASVAGSVERVNKLICVKALKTRYIGEVGD 82 + +V+PGD ++T+ G+GTY+ K+ A + G ++ + V LK RY VGD Sbjct: 1 MRKIVLPGDLLSTNP-RAAGYGTYVEGGKVYAKIIGLFDQTETHVRVIPLKGRYTPSVGD 59 Query: 83 IVVGRITEVQQKRWKVETNSRLDSVLLLSSMNLPGGELRRRSAEDELAMRGFLQEGDLIS 142 +V+G I EV W V+ S + L +S E++ +E+ L GD I Sbjct: 60 VVIGIIREVAANGWAVDIYSPYQAFLPVSE----NPEMKPNKKPNEV-----LDIGDAII 110 Query: 143 AEVQAVFSDGAVSLHTRSLKYGKLGQGVLVQVSPSLVKR---QKTHFHDL---PCGASVI 196 A+V + V+L + + G +V ++P+ V R +K L ++ Sbjct: 111 AKVLNIDPKMKVTLTMKDRICRPIRFGRIVAINPARVPRVIGKKGSMIKLLKSELDVQIV 170 Query: 197 LGNNGFIWI 205 +G NG IW+ Sbjct: 171 VGQNGLIWV 179 >5OKZ-G nrPDB Length = 244 Score = 190 bits (482), Expect = 7e-49, Method: Composition-based stats. Identities = 51/212 (24%), Positives = 75/212 (35%), Gaps = 35/212 (16%) Query: 19 GRDTKKHLVVPGDTITTDT--GFMRGHGTYMG-EEKLIASVAGSVERVN-------KLIC 68 G D+ + PGD+ D G G Y + I V V V+ + Sbjct: 1 GPDSMSTFIFPGDSFPVDPTTPVKLGPGIYCDPNTQEIRPVNTGVLHVSAKGKSGVQTAY 60 Query: 69 VKALKTRYIGEVGDIVVGRITEVQQKRWKVETNSRLDSVLLLSSMNLPGGELRRRSAEDE 128 + RYI V D V+G I +KV + S + LS M P + R Sbjct: 61 IDYSSKRYIPSVNDFVIGVIIGTFSDSYKVSLQN-FSSSVSLSYMAFPNASKKNRPT--- 116 Query: 129 LAMRGFLQEGDLISAEVQAVFSDGAVSLHT------RSLKYGKLGQGVLVQVSPSLVKRQ 182 LQ GDL+ A V + + R +G L G+++ V+ + RQ Sbjct: 117 ------LQVGDLVYARVCTAEKELEAEIECFDSTTGRDAGFGILEDGMIIDVNLNFA-RQ 169 Query: 183 KTHFHDLP--------CGASVILGNNGFIWIY 206 +D P V +G NG IW+ Sbjct: 170 LLFNNDFPLLKVLAAHTKFEVAIGLNGKIWVK 201 >2JEB-I nrPDB Length = 251 Score = 165 bits (418), Expect = 2e-41, Method: Composition-based stats. Identities = 48/216 (22%), Positives = 84/216 (38%), Gaps = 22/216 (10%) Query: 24 KHLVVPGDTITT---DTGFMRGHGTYMGEEKLIASVAGSVERVNKLICVKALKTR-YIGE 79 + +VVPG+ + + K ++V G + + V L+ Y + Sbjct: 16 RSIVVPGELLAEGEFQIPWS--PYILKINSKYYSTVVGLFDVKDTQFEVIPLEGSFYYPK 73 Query: 80 VGDIVVGRITEVQQKRWKVETNSRLDSVLLLSSMNLPGGELRRRSAEDELAMRGFLQEGD 139 + DIV+G + +V+ W V+ + + LP L RS +R +L GD Sbjct: 74 INDIVIGLVEDVEIYGWVVDIKAPYKAY-------LPASNLLGRSINVGEDLRRYLDVGD 126 Query: 140 LISAEVQAVFSDGAVSLHTRSLKYGKLGQGVLVQVSPSLVKR----QKTHFHDL--PCGA 193 + A ++ L + G++ G+++ + P V R K+ + L G Sbjct: 127 YVIARIENFDRSIDPVLSVKGKDLGRVSNGIVIDIMPVKVPRVIGKNKSMYETLTSKSGC 186 Query: 194 SVILGNNGFIWIYPTPEHKEE---EAGGFIANLEPV 226 S+ + NNG IW EE EA I N + Sbjct: 187 SIFVANNGRIWATCPSRFSEEILIEAIRKIENESHI 222 >2JA9-A nrPDB Length = 175 Score = 129 bits (323), Expect = 2e-30, Method: Composition-based stats. Identities = 38/147 (25%), Positives = 55/147 (37%), Gaps = 25/147 (17%) Query: 74 TRYIGEVGDIVVGRITEVQQKRWKVETNSRLDSVLLLSSMNLPGGELRRRSAEDELAMRG 133 RYI V D V+G I +KV + S + LS M P + R Sbjct: 1 KRYIPSVNDFVIGVIIGTFSDSYKVSLQN-FSSSVSLSYMAFPNASKKNRPT-------- 51 Query: 134 FLQEGDLISAEVQAVFSDGAVSLHT------RSLKYGKLGQGVLVQVSPSLVKRQKTHFH 187 LQ GDL+ A V + + R +G L G+++ V+ + RQ + Sbjct: 52 -LQVGDLVYARVCTAEKELEAEIECFDSTTGRDAGFGILEDGMIIDVNLNFA-RQLLFNN 109 Query: 188 DLP--------CGASVILGNNGFIWIY 206 D P V +G NG IW+ Sbjct: 110 DFPLLKVLAAHTKFEVAIGLNGKIWVK 136 >2Z0S-A nrPDB Length = 235 Score = 127 bits (318), Expect = 6e-30, Method: Composition-based stats. Identities = 46/186 (24%), Positives = 77/186 (41%), Gaps = 13/186 (6%) Query: 25 HLVVPGDTITTDTGFMRGHGTYMGEEKLIASVAGSVERVNKLICV-KALKTRYIGEVGDI 83 +VVPG+ + + + K V E+ + LK Y+ + GD+ Sbjct: 10 RIVVPGEPLPEEVEASPPYVIDYKGVKRATVVGLLREKGDGGGRAFVKLKEIYVPQAGDV 69 Query: 84 VVGRITEVQQKRWKVETNSRLDSVLLLSSMNLPGGELRRRSAEDELAMRGFLQEGDLISA 143 V+G I V W V+ NS V +LS + G A D+ M+ L+ GD I A Sbjct: 70 VIGLIQSVGIMNWFVDINSPY--VAVLSVQDFLGRPF--NPAVDD--MQSLLKVGDYIKA 123 Query: 144 EVQAVFSDGAVSLHTRSLKYGKLGQGVLVQVSPSLVK----RQKTHFHDLP--CGASVIL 197 +V A + L + G++ +G +V++SP+ V R+ + L + + Sbjct: 124 KVVAFDKTRSPLLTVQGEGLGRIVRGKIVEISPAKVPRVIGRKMSMLKTLEEKTECKIFV 183 Query: 198 GNNGFI 203 NG I Sbjct: 184 ARNGRI 189 >6D6Q-G nrPDB Length = 277 Score = 70.5 bits (171), Expect = 9e-13, Method: Composition-based stats. Identities = 40/183 (21%), Positives = 70/183 (38%), Gaps = 24/183 (13%) Query: 69 VKALKTRYIGEVGDIVVGRITEVQQKRWKVETNSRLDSVLLLSSMNLPGGELRRRSAEDE 128 V + + RY+ GD V+G +T +KV+ + LS ++ G R R Sbjct: 104 VDSQQKRYVPVKGDHVIGIVTAKSGDIFKVDVGGSEPA--SLSYLSFEGATKRNRPN--- 158 Query: 129 LAMRGFLQEGDLISAEVQAVFSDGAVSLHT-----RSLKYGKLG-QGVLVQVSPSLVKRQ 182 +Q GDLI + D + R+ G +G G+L +V+ L+++ Sbjct: 159 ------VQVGDLIYGQFVVANKDMEPEMVCIDSCGRANGMGVIGQDGLLFKVTLGLIRKL 212 Query: 183 KTHFHDLPCGA------SVILGNNGFIWIY-PTPEHKEEEAGGFIANLEPVSLADREVIS 235 ++ ++ G NG IW+ T + A A S +++ S Sbjct: 213 LAPDCEIIQEVGKLHPLEIVFGMNGRIWVKAKTIQQTLILANILEACEHMTSDQRKQIFS 272 Query: 236 RLR 238 RL Sbjct: 273 RLA 275 >2NN6-I nrPDB Length = 209 Score = 35.5 bits (80), Expect = 0.031, Method: Composition-based stats. Identities = 28/150 (18%), Positives = 64/150 (42%), Gaps = 7/150 (4%) Query: 25 HLVVPGDTITTDTGFMRGHGTYMGEEKLIASVAGSVERVNK------LICVKALKTRYIG 78 +PG+ + G GTY + +S+AG + + ++ + V+ +++ + Sbjct: 20 RYCIPGERLCNLEEGSPGSGTYTRHGYIFSSLAGCLMKSSENGALPVVSVVRETESQLLP 79 Query: 79 EVGDIVVGRITEVQQKRWKVETNSRLDSVLLLSSMNLPGGELRRRSAEDELAMRGFLQEG 138 +VG IV +++ + + KV L S E R + +D++ + + G Sbjct: 80 DVGAIVTCKVSSINSRFAKVHILYVGSMPLKNSFRGTIRKEDVRATEKDKVEIYKSFRPG 139 Query: 139 DLISAEVQAV-FSDGAVSLHTRSLKYGKLG 167 D++ A+V ++ + L T + G + Sbjct: 140 DIVLAKVISLGDAQSNYLLTTAENELGVVV 169 >1GO3-E nrPDB Length = 187 Score = 33.2 bits (74), Expect = 0.13, Method: Composition-based stats. Identities = 19/98 (19%), Positives = 36/98 (36%), Gaps = 6/98 (6%) Query: 76 YIGEVGDIVVGRITEVQQKRWKVETNSRLDSVLLLSSMNLPGGELRRRSAEDELAMRGFL 135 YI E+ +++ G + +V + V + + M+ +R A L Sbjct: 77 YIPEMYELIEGEVVDVVEFGSFVRLGPLDGLIHVSQIMDDYVSYDPKREAIIGKETGKVL 136 Query: 136 QEGDLISAEVQAVF------SDGAVSLHTRSLKYGKLG 167 + GD + A + A+ ++L R GKL Sbjct: 137 EIGDYVRARIVAISLKAERKRGSKIALTMRQPYLGKLE 174 >1YZ6-A nrPDB Length = 274 Score = 31.2 bits (69), Expect = 0.54, Method: Composition-based stats. Identities = 17/90 (18%), Positives = 31/90 (34%), Gaps = 9/90 (10%) Query: 71 ALKTRYIGEVGDIVVGRITEVQQKRWKVETNSRLDSVLLLSSMNLPGGELRRRSAEDELA 130 + R E G+ VV + + +E + ++ R Sbjct: 1 PRRAREYPEEGEFVVATVKRIHNYGAFLELD-EYPGKEAFMHISEVASTWVRN------- 52 Query: 131 MRGFLQEGDLISAEVQAVFS-DGAVSLHTR 159 +R +L+EG + A+V V G + L R Sbjct: 53 IRDYLKEGQKVVAKVIRVDPRKGHIDLSLR 82 >4S3P-A nrPDB Length = 696 Score = 29.3 bits (64), Expect = 1.9, Method: Composition-based stats. Identities = 12/68 (17%), Positives = 25/68 (36%) Query: 84 VVGRITEVQQKRWKVETNSRLDSVLLLSSMNLPGGELRRRSAEDELAMRGFLQEGDLISA 143 +VG++ +KV + P + + D +RG+ + GDL Sbjct: 505 IVGKLRSSGVYSYKVLYFENDHEKTFRAPKAYPEQSMAVAATHDLPTLRGYWECGDLTLG 564 Query: 144 EVQAVFSD 151 + ++ D Sbjct: 565 KTLGLYPD 572 >4OFL-A nrPDB Length = 499 Score = 28.9 bits (63), Expect = 3.0, Method: Composition-based stats. Identities = 28/137 (20%), Positives = 50/137 (36%), Gaps = 19/137 (13%) Query: 170 VLVQVSPSLVKRQKTHFHDLPCGASVILG--NNGFIWIYP-----------TPEHKEEEA 216 V + + Q + S+ +G NN +W+ P TP K++ Sbjct: 185 VFLDEDSAFAAAQSGQLGVVRIPPSMAVGSVNNMKLWVRPSVENRGIVFPTTPAGKKDAH 244 Query: 217 GGFIANLEPVSLADREVISRLRNCIISLVTQRMMLYDTSILYCYEASLPHQIKDILKPEI 276 G I N +A R I+ N L+ ++M Y LP D Sbjct: 245 GYPIGNDVTADVAIRRAINYAIN--RQLLADQIMEGHAIPAYTGVQGLPWNNPD----SA 298 Query: 277 MEEIVMETRQRLLEQEG 293 +++ ++ +++LEQ G Sbjct: 299 IKDGDIDKAKQILEQAG 315 >3M7N-A nrPDB Length = 179 Score = 28.2 bits (61), Expect = 4.5, Method: Composition-based stats. Identities = 23/81 (28%), Positives = 47/81 (58%), Gaps = 4/81 (4%) Query: 25 HLVVPGDTITTDTGFMRGHGTYMGEEKLIASVAGSVERVNKLICVKALKTRYIGEV--GD 82 V+PGD I + +++G G Y +L A+VAG + +++ V+++ I E+ GD Sbjct: 2 RFVMPGDRIGSAEEYVKGEGVYEEGGELFAAVAGKLIIKDRVAKVESISP--IPEIVKGD 59 Query: 83 IVVGRITEVQQKRWKVETNSR 103 +V+GR+ +++ +E +S+ Sbjct: 60 VVLGRVVDLRNSIALIEVSSK 80 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.314 0.129 0.325 Lambda K H 0.267 0.0393 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 9,647,185 Number of Sequences: 36641 Number of extensions: 339674 Number of successful extensions: 1047 Number of sequences better than 10.0: 20 Number of HSP's better than 10.0 without gapping: 18 Number of HSP's successfully gapped in prelim test: 20 Number of HSP's that attempted gapping in prelim test: 995 Number of HSP's gapped (non-prelim): 43 length of query: 293 length of database: 10,336,785 effective HSP length: 96 effective length of query: 197 effective length of database: 6,819,249 effective search space: 1343392053 effective search space used: 1343392053 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.5 bits) S2: 58 (27.0 bits)