BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q13630 (321 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 4BKP-A nrPDB 661 0.0 6AQY-A nrPDB 361 e-100 1GFS-A nrPDB 154 5e-38 1KEU-A nrPDB 52 4e-07 6BWL-A nrPDB 49 3e-06 1BXK-A nrPDB 45 3e-05 1OC2-A nrPDB 44 7e-05 1R66-A nrPDB 44 1e-04 2Q1W-A nrPDB 42 3e-04 1VL0-A nrPDB 42 5e-04 4WKG-A nrPDB 41 6e-04 1I3M-A nrPDB 41 7e-04 3RUE-A nrPDB 41 7e-04 3M2P-A nrPDB 41 8e-04 4WOK-A nrPDB 40 0.002 2PZM-A nrPDB 39 0.002 4WPG-A nrPDB 39 0.003 2C20-A nrPDB 39 0.003 1EQ2-A nrPDB 38 0.005 2HUN-A nrPDB 38 0.006 2X86-A nrPDB 37 0.012 2PK3-A nrPDB 36 0.023 3SC6-A nrPDB 35 0.049 3ENK-A nrPDB 35 0.055 1Z45-A nrPDB 34 0.066 4LIS-A nrPDB 34 0.075 2NM0-A nrPDB 33 0.15 6BI4-A nrPDB 32 0.31 2V0O-A nrPDB 32 0.42 4KTT-E nrPDB 31 0.59 6CCF-A nrPDB 30 1.7 3BRE-A nrPDB 28 4.2 3RWB-A nrPDB 28 4.5 6GER-A nrPDB 28 5.7 5NUE-A nrPDB 28 6.3 3SS3-A nrPDB 28 6.6 5W2J-A nrPDB 28 7.8 5WJ6-A nrPDB 28 7.9 4BQM-A nrPDB 27 8.3 >4BKP-A nrPDB Length = 336 Score = 661 bits (1706), Expect = 0.0, Method: Compositional matrix adjust. Identities = 315/315 (100%), Positives = 315/315 (100%) Query: 7 SMRILVTGGSGLVGKAIQKVVADGAGLPGEDWVFVSSKDADLTDTAQTRALFEKVQPTHV 66 SMRILVTGGSGLVGKAIQKVVADGAGLPGEDWVFVSSKDADLTDTAQTRALFEKVQPTHV Sbjct: 22 SMRILVTGGSGLVGKAIQKVVADGAGLPGEDWVFVSSKDADLTDTAQTRALFEKVQPTHV 81 Query: 67 IHLAAMVGGLFRNIKYNLDFWRKNVHMNDNVLHSAFEVGARKVVSCLSTCIFPDKTTYPI 126 IHLAAMVGGLFRNIKYNLDFWRKNVHMNDNVLHSAFEVGARKVVSCLSTCIFPDKTTYPI Sbjct: 82 IHLAAMVGGLFRNIKYNLDFWRKNVHMNDNVLHSAFEVGARKVVSCLSTCIFPDKTTYPI 141 Query: 127 DETMIHNGPPHNSNFGYSYAKRMIDVQNRAYFQQYGCTFTAVIPTNVFGPHDNFNIEDGH 186 DETMIHNGPPHNSNFGYSYAKRMIDVQNRAYFQQYGCTFTAVIPTNVFGPHDNFNIEDGH Sbjct: 142 DETMIHNGPPHNSNFGYSYAKRMIDVQNRAYFQQYGCTFTAVIPTNVFGPHDNFNIEDGH 201 Query: 187 VLPGLIHKVHLAKSSGSALTVWGTGNPRRQFIYSLDLAQLFIWVLREYNEVEPIILSVGE 246 VLPGLIHKVHLAKSSGSALTVWGTGNPRRQFIYSLDLAQLFIWVLREYNEVEPIILSVGE Sbjct: 202 VLPGLIHKVHLAKSSGSALTVWGTGNPRRQFIYSLDLAQLFIWVLREYNEVEPIILSVGE 261 Query: 247 EDEVSIKEAAEAVVEAMDFHGEVTFDTTKSDGQFKKTASNSKLRTYLPDFRFTPFKQAVK 306 EDEVSIKEAAEAVVEAMDFHGEVTFDTTKSDGQFKKTASNSKLRTYLPDFRFTPFKQAVK Sbjct: 262 EDEVSIKEAAEAVVEAMDFHGEVTFDTTKSDGQFKKTASNSKLRTYLPDFRFTPFKQAVK 321 Query: 307 ETCAWFTDNYEQARK 321 ETCAWFTDNYEQARK Sbjct: 322 ETCAWFTDNYEQARK 336 >6AQY-A nrPDB Length = 341 Score = 361 bits (927), Expect = e-100, Method: Compositional matrix adjust. Identities = 166/317 (52%), Positives = 226/317 (71%), Gaps = 7/317 (2%) Query: 10 ILVTGGSGLVGKAIQKVVADGAGLPGEDWVFVSSKDADLTDTAQTRALFEKVQPTHVIHL 69 ILVTGG+GL GKA++ +V + G+ WVF+ SKD DL D + FEK +PT+VIHL Sbjct: 27 ILVTGGTGLFGKAVEHIVKK-EQIKGK-WVFLGSKDGDLRDADACKQPFEKYRPTYVIHL 84 Query: 70 AAMVGGLFRNIKYNLDFWRKNVHMNDNVLHSAFEVGARKVVSCLSTCIFPDKTTYPIDET 129 AA VGGLF+N+ + + FW NV+MN+N+L ++ G +K +SCLSTC+FPDK YPI E Sbjct: 85 AAFVGGLFKNMNFKVSFWLDNVNMNNNILTCCYDFGVKKTISCLSTCVFPDKIEYPITEE 144 Query: 130 MIHNGPPHNSNFGYSYAKRMIDVQNRAYFQQ-----YGCTFTAVIPTNVFGPHDNFNIED 184 +H GPPH SN Y+YAKRM+D+ R Y ++ C FT+VIPTN+FGPHDNFN+E Sbjct: 145 KLHEGPPHFSNNAYAYAKRMLDMLGRWYNEKAVNEGKSCLFTSVIPTNLFGPHDNFNVEA 204 Query: 185 GHVLPGLIHKVHLAKSSGSALTVWGTGNPRRQFIYSLDLAQLFIWVLREYNEVEPIILSV 244 GHVLPGL+HK + A+ +G+ V+G+G P RQF+YS D A++ +W + Y EPI+L V Sbjct: 205 GHVLPGLMHKCYKAQQNGTDFVVFGSGKPLRQFLYSHDAARMLLWTMFNYQSEEPIMLCV 264 Query: 245 GEEDEVSIKEAAEAVVEAMDFHGEVTFDTTKSDGQFKKTASNSKLRTYLPDFRFTPFKQA 304 EEDE SI + A+ + +A +F G + FDT+K+DGQ+KKT+SN+K P F++TPF+QA Sbjct: 265 SEEDEKSIGQVAQTIKDAFNFTGNMVFDTSKADGQYKKTSSNAKFLRLNPTFQYTPFEQA 324 Query: 305 VKETCAWFTDNYEQARK 321 +KET WF +NYE ARK Sbjct: 325 IKETVQWFLENYETARK 341 >1GFS-A nrPDB Length = 321 Score = 154 bits (389), Expect = 5e-38, Method: Compositional matrix adjust. Identities = 91/320 (28%), Positives = 166/320 (51%), Gaps = 12/320 (3%) Query: 9 RILVTGGSGLVGKAIQKVVADGAGLPGEDWVFVSSKDADLTDTAQTRALFEKVQPTHVIH 68 R+ + G G+VG AI++ + + + V + + +L D+ F + V Sbjct: 5 RVFIAGHRGMVGSAIRRQLEQRGDV---ELVLRTRDELNLLDSRAVHDFFASERIDQVYL 61 Query: 69 LAAMVGGLFRNIKYNLDFWRKNVHMNDNVLHSAFEVGARKVVSCLSTCIFPDKTTYPIDE 128 AA VGG+ N Y DF +N+ + N++H+A + K++ S+CI+P P+ E Sbjct: 62 AAAKVGGIVANNTYPADFIYQNMMIESNIIHAAHQNDVNKLLFLGSSCIYPKLAKQPMAE 121 Query: 129 TMIHNGPPHNSNFGYSYAKRMIDVQNRAYFQQYGCTFTAVIPTNVFGPHDNFNIEDGHVL 188 + + G +N Y+ AK +Y +QYG + +V+PTN++GPHDNF+ + HV+ Sbjct: 122 SELLQGTLEPTNEPYAIAKIAGIKLCESYNRQYGRDYRSVMPTNLYGPHDNFHPSNSHVI 181 Query: 189 PGLIHKVHLAKSSGSA-LTVWGTGNPRRQFIYSLDLAQLFIWVLREYNEV-----EPII- 241 P L+ + H A + + + VWG+G P R+F++ D+A I V+ +EV +P++ Sbjct: 182 PALLRRFHEATAQNAPDVVVWGSGTPMREFLHVDDMAAASIHVMELAHEVWLENTQPMLS 241 Query: 242 -LSVGEEDEVSIKEAAEAVVEAMDFHGEVTFDTTKSDGQFKKTASNSKLRTYLPDFRFTP 300 ++VG + +I+E A+ + + + + G V FD +K DG +K ++L L + Sbjct: 242 HINVGTGVDCTIRELAQTIAKVVGYKGRVVFDASKPDGTPRKLLDVTRLHQ-LGWYHEIS 300 Query: 301 FKQAVKETCAWFTDNYEQAR 320 + + T WF +N ++ R Sbjct: 301 LEAGLASTYQWFLENQDRFR 320 >1KEU-A nrPDB Length = 361 Score = 51.6 bits (122), Expect = 4e-07, Method: Compositional matrix adjust. Identities = 79/353 (22%), Positives = 133/353 (37%), Gaps = 61/353 (17%) Query: 8 MRILVTGGSGLVGKAIQK----------VVADGAGLPG--EDWVFVSSKD------ADLT 49 M+IL+TGG+G +G A+ + V D G E +S + AD+ Sbjct: 1 MKILITGGAGFIGSAVVRHIIKNTQDTVVNIDKLTYAGNLESLSDISESNRYNFEHADIC 60 Query: 50 DTAQTRALFEKVQPTHVIHLAAMVGGLFRNIKYNLDFWRKNVHMNDNVLHSAFEVGARKV 109 D+A+ +FE+ QP V+HLAA + R+I F N+ ++ EV ARK Sbjct: 61 DSAEITRIFEQYQPDAVMHLAAE-SHVDRSITGPAAFIETNIVGT----YALLEV-ARKY 114 Query: 110 VSCLST-------------------CIFPDKTTYPIDETMIHNGPPHNSNFGYSYAKRMI 150 S L PD+ + + + + YS +K Sbjct: 115 WSALGEDKKNNFRFHHISTDEVYGDLPHPDEVENSVTLPLFTETTAYAPSSPYSASKASS 174 Query: 151 DVQNRAYFQQYGCTFTAVIPTNVFGPHDNFNIEDGHVLPGLIHKVHLAKSSGSALTVWGT 210 D RA+ + YG +N +GP+ H LI V L G L ++G Sbjct: 175 DHLVRAWRRTYGLPTIVTNCSNNYGPY--------HFPEKLIPLVILNALEGKPLPIYGK 226 Query: 211 GNPRRQFIYSLDLAQLFIWVLREYNEVEPIILSVGEEDEVSIKEAA--------EAVVEA 262 G+ R ++Y D A+ V+ E E ++G +E + E V +A Sbjct: 227 GDQIRDWLYVEDHARALHMVVTEGKAGE--TYNIGGHNEKKNLDVVFTICDLLDEIVPKA 284 Query: 263 MDFHGEVTFDTTKSDGQFKKTASNSKLRTYLPDFRFTPFKQAVKETCAWFTDN 315 + ++T+ + + K+ L F+ +++T W+ N Sbjct: 285 TSYREQITYVADRPGHDRRYAIDAGKISRELGWKPLETFESGIRKTVEWYLAN 337 >6BWL-A nrPDB Length = 328 Score = 49.3 bits (116), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 59/269 (21%), Positives = 112/269 (41%), Gaps = 29/269 (10%) Query: 8 MRILVTGGSGLVGK-AIQKVVADGAGLPGEDWV---FVSSKDADLTDTAQTRALFEKVQP 63 M+ILVTGG+G +G+ +++++ D E W+ +S A++T+ A L + +Q Sbjct: 1 MKILVTGGAGFIGRWVVKRLLQD----KHEVWILDNLANSTTANITEFAHDLNLKQCIQG 56 Query: 64 THVIHLAAMVGGLFRNIKYNLDF-WRKNVHMNDNV--LHSAFEVGARKVVSCLSTCIFPD 120 I +V LF N ++L + ++++ D++ + FE + L C+ D Sbjct: 57 D--IKDKKLVAQLFENNSFDLCYHLAASINVQDSIDDARATFENDTIGTFNLLEQCLNYD 114 Query: 121 KTTYPIDETMIHNGPPHNSNF--------GYSYAKRMIDVQNR--AYFQQYGCTFTAVIP 170 + M+++ + YA I +N +Y+ Y + P Sbjct: 115 VKMVFMSTCMVYDKATNIQGISELDPIKPASPYAGSKIAAENMVLSYYYAYKLPVVVIRP 174 Query: 171 TNVFGPHDNFNIEDGHVLPGLIHKVHLAKSSGSALTVWGTGNPRRQFIYSLDLAQLFIWV 230 N +GP E G V + +K+ L ++G G R +Y D A F+ Sbjct: 175 FNTYGPFQKTGGEGGVVAIFINNKL-----DNVPLNIYGDGKQTRDLLYVEDCAD-FVVA 228 Query: 231 LREYNEVEPIILSVGEEDEVSIKEAAEAV 259 + I++ G ++SI + AE + Sbjct: 229 AGYSAKANGHIINAGTGQDISINKLAELI 257 >1BXK-A nrPDB Length = 355 Score = 45.4 bits (106), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 74/346 (21%), Positives = 127/346 (36%), Gaps = 53/346 (15%) Query: 9 RILVTGGSGLVGKAIQK----------VVADGAGLPG-----------EDWVFVSSKDAD 47 +IL+TGG+G +G A+ + VV D G E + F + D Sbjct: 3 KILITGGAGFIGSALVRYIINETSDAVVVVDKLTYAGNLMSLAPVAQSERFAF---EKVD 59 Query: 48 LTDTAQTRALFEKVQPTHVIHLAAMVGGLFRNIKYNLDFWRKNVHMNDNVLHSAFEVGAR 107 + D A+ +F + QP V+HLAA + R+I F N+ +L +A Sbjct: 60 ICDRAELARVFTEHQPDCVMHLAAE-SHVDRSIDGPAAFIETNIVGTYTLLEAARAYWNA 118 Query: 108 KVVSCLSTCIFPDKTTYPI------DETMIHNGPPHNSNFGYSYAKRMIDVQNRAYFQQY 161 S F +T + + P+ + YS +K D RA+ + Y Sbjct: 119 LTEDKKSAFRFHHISTDEVYGDLHSTDDFFTETTPYAPSSPYSASKASSDHLVRAWLRTY 178 Query: 162 GCTFTAVIPTNVFGPHDNFNIEDGHVLPGLIHKVHLAKSSGSALTVWGTGNPRRQFIYSL 221 G +N +GP+ H LI + L +G +L V+G G R ++Y Sbjct: 179 GLPTLITNCSNNYGPY--------HFPEKLIPLMILNALAGKSLPVYGNGQQIRDWLYVE 230 Query: 222 DLAQLFIWVLREYNEVEPIILSVGEEDEVSIKEAAEAVVEAMD------------FHGEV 269 D A+ V E ++G +E + E + E ++ + + Sbjct: 231 DHARALYCVATTGKVGE--TYNIGGHNERKNLDVVETICELLEELAPNKPHGVAHYRDLI 288 Query: 270 TFDTTKSDGQFKKTASNSKLRTYLPDFRFTPFKQAVKETCAWFTDN 315 TF + + SK+ L F+ +++T W+ N Sbjct: 289 TFVADRPGHDLRYAIDASKIARELGCVPQETFESGMRKTVQWYLAN 334 >1OC2-A nrPDB Length = 348 Score = 44.3 bits (103), Expect = 7e-05, Method: Compositional matrix adjust. Identities = 49/186 (26%), Positives = 85/186 (45%), Gaps = 22/186 (11%) Query: 137 HNSNFGYSYAKRMIDVQNRAYFQQYGCTFTAVIPTNVFGPHDNFNIEDGHVLPGLIHKVH 196 +N + YS K D+ +A+ + +G T +N +GP+ + +P I + Sbjct: 155 YNPSSPYSSTKAASDLIVKAWVRSFGVKATISNCSNNYGPYQHIE----KFIPRQITNI- 209 Query: 197 LAKSSGSALTVWGTGNPRRQFIYSLDLAQLFIWVLREYNEVEPIILSVGEEDEVSIKEAA 256 +G ++G G R +I++ D + +W + + L +G + E + KE Sbjct: 210 ---LAGIKPKLYGEGKNVRDWIHTNDHST-GVWAILTKGRMGETYL-IGADGEKNNKEVL 264 Query: 257 EAVVEAM----DFHGEVTFDTTKSDGQFKKTASNSKLRTYL---PDFRFTPFKQAVKETC 309 E ++E M D + VT D D ++ AS KLR L P +FT F + ++ET Sbjct: 265 ELILEKMGQPKDAYDHVT-DRAGHDLRYAIDAS--KLRDELGWTP--QFTDFSEGLEETI 319 Query: 310 AWFTDN 315 W+TDN Sbjct: 320 QWYTDN 325 >1R66-A nrPDB Length = 337 Score = 43.9 bits (102), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 67/329 (20%), Positives = 121/329 (36%), Gaps = 36/329 (10%) Query: 8 MRILVTGGSGLVGKAIQKVVADGA--GLPGEDWVFVSSK------------DADLT---- 49 MR+LVTGG+G +G + + GA +P ++ + + S DAD Sbjct: 1 MRLLVTGGAGFIGSHFVRQLLAGAYPDVPADEVIVLDSLTYAGNRANLAPVDADPRLRFV 60 Query: 50 --DTAQTRALFEKVQPTHVIHLAAMVGGLFRNIKYNLDFWRKNVHMNDNVLHSAFEVGAR 107 D L +++ I A + R+I F NV +L A + G Sbjct: 61 HGDIRDAGLLARELRGVDAIVHFAAESHVDRSIAGASVFTETNVQGTQTLLQCAVDAGVG 120 Query: 108 KVVSCLSTCIFPDKTTYPIDETMIHNGPPHNSNFGYSYAKRMIDVQNRAYFQQYGCTFTA 167 +VV + D+ ID P N Y+ +K D+ RAY + YG Sbjct: 121 RVVH-----VSTDEVYGSIDSGSWTESSPLEPNSPYAASKAGSDLVARAYHRTYGLDVRI 175 Query: 168 VIPTNVFGPHDNFNIEDGHVLPGLIHKVHLAKSSGSALTVWGTGNPRRQFIYSLDLAQLF 227 N +GP+ + ++P + + G L ++G G R+++++ D + Sbjct: 176 TRCCNNYGPYQHPE----KLIPLFVTNL----LDGGTLPLYGDGANVREWVHTDDHCRGI 227 Query: 228 IWVLREYNEVEPIILSVGEEDEVSIKEAAEAVVEAMDFHGEVTFDTTKSDGQ-FKKTASN 286 VL E I +G E++ +E +++++ G + + Sbjct: 228 ALVLAGGRAGE--IYHIGGGLELTNRELTGILLDSLGADWSSVRKVADRKGHDLRYSLDG 285 Query: 287 SKLRTYLPDFRFTPFKQAVKETCAWFTDN 315 K+ L F + T W+ +N Sbjct: 286 GKIERELGYRPQVSFADGLARTVRWYREN 314 >2Q1W-A nrPDB Length = 333 Score = 42.0 bits (97), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 76/332 (22%), Positives = 123/332 (37%), Gaps = 51/332 (15%) Query: 4 PQGS--MRILVTGGSGLVGKAIQKVVAD-GAGLPGEDWVFVSSKD------------ADL 48 P+GS ++ +TG G +G I +++ + G + G D ++ + Sbjct: 16 PRGSHMKKVFITGICGQIGSHIAELLLERGDKVVGIDNFATGRREHLKDHPNLTFVEGSI 75 Query: 49 TDTAQTRALFEKVQPTHVIHLAAMVGGLFRNIKYNLDFWRKNVHMN----DNVLHSAFEV 104 D A L +QP V+H AA + D W + N NV+ +A + Sbjct: 76 ADHALVNQLIGDLQPDAVVHTAASYK--------DPDDWYNDTLTNCVGGSNVVQAAKKN 127 Query: 105 GARKVVSCLSTCIFPDKTTYPIDETMIHNGPPHNSNFGYSYAKRMIDVQNRAYFQQYGCT 164 + V + + K PI + + + P + +N Y+ +K N Y + G Sbjct: 128 NVGRFVYFQTALCYGVK---PIQQPVRLDHPRNPANSSYAISKSA----NEDYLEYSGLD 180 Query: 165 FTAVIPTNVFGPHDNFNIEDGHVLPGLIHKVHLAKSSGSALTVWGTGNPRRQFIYSLDLA 224 F NV GP N+ LP ++ S G V RR F++ DLA Sbjct: 181 FVTFRLANVVGPR---NVSGP--LPIFFQRL----SEGKKCFVT---KARRDFVFVKDLA 228 Query: 225 QLFIWVLREYNEVEPIILSVGEEDEVSIKEAAEAVVEAMDF--HGEVTFDTTKSDGQFKK 282 + +R + V +V+IKE +AVVEAM + E D Sbjct: 229 R---ATVRAVDGVGHGAYHFSSGTDVAIKELYDAVVEAMALPSYPEPEIRELGPDDAPSI 285 Query: 283 TASNSKLRTYLPDFRFTPFKQAVKETCAWFTD 314 S+ FTP K+ V A+F + Sbjct: 286 LLDPSRTIQDFGKIEFTPLKETVAAAVAYFRE 317 >1VL0-A nrPDB Length = 292 Score = 41.6 bits (96), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 34/123 (27%), Positives = 61/123 (49%), Gaps = 10/123 (8%) Query: 8 MRILVTGGSGLVGKAIQKVVADGAGLPGEDWVFVSS--KDADLTDTAQTRALFEKVQPTH 65 M+IL+TG +G +G+ IQK L G++ + + +D D+T+ F + +P Sbjct: 13 MKILITGANGQLGREIQK------QLKGKNVEVIPTDVQDLDITNVLAVNKFFNEKKPNV 66 Query: 66 VIHLAAMVGGLFRNIKYNLDFWRKNVHMNDNVLHSAFEVGARKVVSCLSTCIFPDKTTYP 125 VI+ AA +Y+L + + N N+ +A+ VGA ++V + +F + P Sbjct: 67 VINCAAHTAVDKCEEQYDLAY-KINAIGPKNLAAAAYSVGA-EIVQISTDYVFDGEAKEP 124 Query: 126 IDE 128 I E Sbjct: 125 ITE 127 >4WKG-A nrPDB Length = 660 Score = 41.2 bits (95), Expect = 6e-04, Method: Compositional matrix adjust. Identities = 40/146 (27%), Positives = 67/146 (45%), Gaps = 10/146 (6%) Query: 127 DETMIHNGPPHNSNFGYSYAKRMIDVQNRAYFQQYGCTFTAVIPTNVFGPH-DNFN---I 182 D + + GP + + YS +K+++D AY ++ G FT P N GP DN N I Sbjct: 447 DHSNLIVGPVNKPRWIYSVSKQLLDRVIWAYGEKEGLQFTLFRPFNWMGPRLDNLNAARI 506 Query: 183 EDGHVLPGLIHKVHLAKSSGSALTVWGTGNPRRQFIYSLD-LAQLFIWVLREYNEVEPII 241 + LI L GS + + G +R F D + L+ + N + I Sbjct: 507 GSSRAITQLI----LNLVEGSPIKLIDGGKQKRCFTDIRDGIEALYRIIENAGNRCDGEI 562 Query: 242 LSVGE-EDEVSIKEAAEAVVEAMDFH 266 +++G E+E SI+E E ++ + + H Sbjct: 563 INIGNPENEASIEELGEMLLASFEKH 588 >1I3M-A nrPDB Length = 348 Score = 41.2 bits (95), Expect = 7e-04, Method: Compositional matrix adjust. Identities = 64/263 (24%), Positives = 103/263 (39%), Gaps = 41/263 (15%) Query: 9 RILVTGGSGLVGK---------AIQKVVAD--------GAGLPGE-------DWVFVSSK 44 ++LVTGG+G +G VV D G LP V + Sbjct: 4 KVLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRSVEFE 63 Query: 45 DADLTDTAQTRALFEKVQPTHVIHLAAMVGGLFRNIKYNLDFWRKNVHMNDNVLHSAFEV 104 + D+ D + LF+K VIH A + + +++ LD++R N+ +L Sbjct: 64 EMDILDQGALQRLFKKYSFMAVIHFAGL-KAMGESVQKPLDYYRVNLTGTIQLLEIMKAH 122 Query: 105 GARKVVSCLSTCIFPDKTTYPIDETMIHNGPPHNSNFGYSYAKRMIDVQNRAYFQQYGCT 164 G + +V S ++ + P+DE P Y +K I+ R Q T Sbjct: 123 GVKNLVFSSSATVYGNPQYLPLDEAH----PTGGCTNPYGKSKFFIEEMIRDLCQA-DKT 177 Query: 165 FTAVIPT--NVFGPHDNFNI-EDGHVLPG--LIHKVHLAKSSGSALTVWGT------GNP 213 + V+ N G H + I ED +P + + +A AL V+G G Sbjct: 178 WNVVLLRYFNPTGAHASGCIGEDPQGIPNNLMPYVSQVAIGRREALNVFGNDYDTEDGTG 237 Query: 214 RRQFIYSLDLAQLFIWVLREYNE 236 R +I+ +DLA+ I LR+ E Sbjct: 238 VRDYIHVVDLAKGHIAALRKLKE 260 >3RUE-A nrPDB Length = 351 Score = 40.8 bits (94), Expect = 7e-04, Method: Compositional matrix adjust. Identities = 51/230 (22%), Positives = 91/230 (39%), Gaps = 12/230 (5%) Query: 36 EDWVFVSSKDADLTDTAQTRALFEKVQPTHVIHLAAMVGGLFRNIKYNLDFWRKNVHMND 95 E W + D+ D + + V HV+H AA+ G + R+I + N+ Sbjct: 76 EQWSRFCFIEGDIRDLTTCEQVMKGVD--HVLHQAAL-GSVPRSIVDPITTNATNITGFL 132 Query: 96 NVLHSAFEVGARKVVSCLSTCIFPDKTTYPIDETMIHNGPPHNSNFGYSYAKRMIDVQNR 155 N+LH+A + S+ + D P E I G P + Y+ K + ++ + Sbjct: 133 NILHAAKNAQVQSFTYAASSSTYGDHPALPKVEENI--GNPLSP---YAVTKYVNEIYAQ 187 Query: 156 AYFQQYGCTFTAVIPTNVFGPHDNFNIEDGHVLPGLIHKVHLAKSSGSALTVWGTGNPRR 215 Y + YG + NVFG + N V+P K A G + + G G R Sbjct: 188 VYARTYGFKTIGLRYFNVFGRRQDPNGAYAAVIP----KWTAAMLKGDDVYINGDGETSR 243 Query: 216 QFIYSLDLAQLFIWVLREYNEVEPIILSVGEEDEVSIKEAAEAVVEAMDF 265 F Y ++ Q+ I + + I +V D ++ E + + + ++ Sbjct: 244 DFCYIDNVIQMNILSALAKDSAKDNIYNVAVGDRTTLNELSGYIYDELNL 293 >3M2P-A nrPDB Length = 311 Score = 40.8 bits (94), Expect = 8e-04, Method: Compositional matrix adjust. Identities = 51/261 (19%), Positives = 111/261 (42%), Gaps = 25/261 (9%) Query: 7 SMRILVTGGSGLVGKAIQKVVADGAGLPGEDWVFVSSKDAD-----LTDTAQTRALFEKV 61 S++I VTGG+G +G+ + + + + P + +K + ++D + + Sbjct: 2 SLKIAVTGGTGFLGQYVVESIKNDGNTPIILTRSIGNKAINDYEYRVSDYTLEDLINQLN 61 Query: 62 QPTHVIHLAAMVGGLFRNIKYNLDFWRKNVHMNDNVLHSAFEVGARKVVSCLSTCIFPDK 121 V+HLAA G + + + N + N+ + +E +V + + D+ Sbjct: 62 DVDAVVHLAATRGSQGK-----ISEFHDNEILTQNLYDACYENNISNIVYASTISAYSDE 116 Query: 122 TTYPIDETMIHNGPPHNSNFGYSYAKRMIDVQNRAYFQQYGCTFTAVIPTNVFGPHDNFN 181 T+ P +E + P + +G S K + Y ++ G + +++G FN Sbjct: 117 TSLPWNEKEL---PLPDLMYGVS--KLACEHIGNIYSRKKGLCIKNLRFAHLYG----FN 167 Query: 182 IEDGHVLPGLIHKVHLAKSSGSALTVWGTGNPRRQFIYSLDLAQLFIWVLREYNEVEPII 241 ++ + +I++ G LT+ +R+F+Y+ D A+ I+ L++ E Sbjct: 168 EKNNY----MINRFFRQAFHGEQLTLHANSVAKREFLYAKDAAKSVIYALKQ--EKVSGT 221 Query: 242 LSVGEEDEVSIKEAAEAVVEA 262 ++G D ++ E A + A Sbjct: 222 FNIGSGDALTNYEVANTINNA 242 >4WOK-A nrPDB Length = 336 Score = 39.7 bits (91), Expect = 0.002, Method: Compositional matrix adjust. Identities = 62/272 (22%), Positives = 109/272 (40%), Gaps = 31/272 (11%) Query: 10 ILVTGGSGLVGKAIQKVVADGAGLPGEDWVFVSSK-----------DADLTDTAQTRALF 58 +LV GG+G +G K++A G G + +S+ + D+ D A+ Sbjct: 14 VLVVGGAGFIGSHTAKLLA-GQGYAPVVYDNLSTGHQSAVRWGDFVEGDILDQARLVETM 72 Query: 59 EKVQPTHVIHLA--AMVGGLFRNIKYNLDFWRKNVHMNDNVLHSAFEVGARKVVSCLSTC 116 EK P VIH A A VG +++ ++R NV ++L + + V+ S Sbjct: 73 EKYAPVAVIHFAASAYVG---ESVEDPAKYYRNNVGGTQSLLDACRLTRTQNVIFSSSCA 129 Query: 117 IFPDKTTYPIDETMIHNGPPHNSNFGYSYAKRMIDVQNRAYFQQYGCTFTAVIPTNVFGP 176 + + PI E N P N Y K + + Y YG + A+ N G Sbjct: 130 TYGVPSRLPIGEGEAQN--PINP---YGRTKLIAEHMLADYAVAYGLRYVALRYFNASGA 184 Query: 177 HDNFNIEDGH-VLPGLIHKVHLAKSSG-SALTVWG------TGNPRRQFIYSLDLAQLFI 228 + + + H LI + +A + L V+G G R +I+ DLA+ + Sbjct: 185 DIDGELGEKHDPETHLIPRAMMAAAGRLDVLEVYGDDYETPDGTCIRDYIHVTDLARAHV 244 Query: 229 WVLREYNEVEP-IILSVGEEDEVSIKEAAEAV 259 + E + +++G SI+E +++ Sbjct: 245 LAVEHLKEAGGNLAVNLGTGRGTSIREIVQSI 276 >2PZM-A nrPDB Length = 330 Score = 39.3 bits (90), Expect = 0.002, Method: Compositional matrix adjust. Identities = 38/149 (25%), Positives = 63/149 (42%), Gaps = 42/149 (28%) Query: 4 PQGS-MRILVTGGSGLVGKAI---------------------QKVVADGAGLPGEDWVFV 41 P+GS MRIL+TGG+G +G + ++V+ AGL Sbjct: 16 PRGSHMRILITGGAGCLGSNLIEHWLPQGHEILVIDNFATGKREVLPPVAGL-------- 67 Query: 42 SSKDADLTDTAQTRALFEKVQPTHVIHLAAMVGGLFRNIKYNLDFWRK----NVHMNDNV 97 S + +TD F+ +PTHV+H AA + D W + NV + NV Sbjct: 68 SVIEGSVTDAGLLERAFDSFKPTHVVHSAAAY--------KDPDDWAEDAATNVQGSINV 119 Query: 98 LHSAFEVGARKVVSCLSTCIFPDKTTYPI 126 +A + G +++++ + + T PI Sbjct: 120 AKAASKAGVKRLLNFQTALCYGRPATVPI 148 >4WPG-A nrPDB Length = 289 Score = 39.3 bits (90), Expect = 0.003, Method: Compositional matrix adjust. Identities = 21/62 (33%), Positives = 37/62 (59%), Gaps = 4/62 (6%) Query: 10 ILVTGGSGLVGKAIQKVVADGAGLPGEDWVFVSSKDADLTDTAQTRALFEKVQPTHVIHL 69 IL+TG +G +G ++ ++ + G D+V V + D+T+ + A+F +V+PT V H Sbjct: 7 ILITGSNGQLGTELRYLLDE----RGVDYVAVDVAEMDITNEDKVEAVFAQVKPTLVYHC 62 Query: 70 AA 71 AA Sbjct: 63 AA 64 >2C20-A nrPDB Length = 330 Score = 38.9 bits (89), Expect = 0.003, Method: Compositional matrix adjust. Identities = 78/328 (23%), Positives = 133/328 (40%), Gaps = 37/328 (11%) Query: 10 ILVTGGSGLVGK-AIQKVVADGAGLPGEDWVFVSSKDA----------DLTDTAQTRALF 58 IL+ GG+G +G A++K+V +G + D + +DA DL D A R +F Sbjct: 4 ILICGGAGYIGSHAVKKLVDEGLSVVVVDNLQTGHEDAITEGAKFYNGDLRDKAFLRDVF 63 Query: 59 EKVQPTHVIHLAA--MVGGLFRNIKYNLDFWRKNVHMNDNVLHSAFEVGARKVVSCLSTC 116 + V+H AA +VG +++ L ++ NV+ +L E K + + Sbjct: 64 TQENIEAVMHFAADSLVG---VSMEKPLQYYNNNVYGALCLLEVMDEFKVDKFIFSSTAA 120 Query: 117 IFPDKTTYPIDETMIHNGPPHNSNFGYSYAKRMIDVQNRAYFQQYGCTFTAVIPTNVFGP 176 + + I E + N P N+ Y K I+ Y Q + NV G Sbjct: 121 TYGEVDVDLITEETMTN--PTNT---YGETKLAIEKMLHWYSQASNLRYKIFRYFNVAGA 175 Query: 177 HDNFNI-ED----GHVLPGLIHKVHLAKSSGSALTVWG------TGNPRRQFIYSLDL-A 224 N I ED H++P L+ +V L + + ++G G R +I+ DL A Sbjct: 176 TPNGIIGEDHRPETHLIP-LVLQVALGQR--EKIMMFGDDYNTPDGTCIRDYIHVEDLVA 232 Query: 225 QLFIWVLREYNEVEPIILSVGEEDEVSIKEAAEAVVEAMDFHGEVTFDTTKSDGQFKKTA 284 F+ + N E ++G + S+KE +AV E + ++ + A Sbjct: 233 AHFLGLKDLQNGGESDFYNLGNGNGFSVKEIVDAVREVTNHEIPAEVAPRRAGDPARLVA 292 Query: 285 SNSKLRTYLP-DFRFTPFKQAVKETCAW 311 S+ K + L D R+ K ++ W Sbjct: 293 SSQKAKEKLGWDPRYVNVKTIIEHAWNW 320 >1EQ2-A nrPDB Length = 310 Score = 38.1 bits (87), Expect = 0.005, Method: Compositional matrix adjust. Identities = 72/325 (22%), Positives = 118/325 (36%), Gaps = 40/325 (12%) Query: 10 ILVTGGSGLVGKAIQKVVADGAGLPG--------EDWVFVSSKDADLTDTAQTRALFEKV 61 I+VTGG+G +G I K + D G+ + FV+ D ++ D ++ Sbjct: 2 IIVTGGAGFIGSNIVKALND-KGITDILVVDNLKDGTKFVNLVDLNIADYMDKEDFLIQI 60 Query: 62 QPTH-------VIHLAAMVGGLFRNIKYNLDFWRKNVHMNDNVLHSAFEVGARKV--VSC 112 + H A + KY +D N + +LH E R++ + Sbjct: 61 MAGEEFGDVEAIFHEGACSSTTEWDGKYMMD---NNYQYSKELLHYCLE---REIPFLYA 114 Query: 113 LSTCIFPDKTTYPIDETMIHNGPPHNSNFGYSYAKRMIDVQNRAYFQQYGCTFTAVIPTN 172 S + +T+ I+ P N Y Y+K + D R + N Sbjct: 115 SSAATYGGRTSDFIESREYE--KPLNV---YGYSKFLFDEYVRQILPEANSQIVGFRYFN 169 Query: 173 VFGPHDNFNIEDGHVLPGLIHKVHLAKSSGSALTVWGTGNPRRQFIYSLDLAQLFIWVLR 232 V+GP + G + H + S G+ N +R F+Y D+A + +W L Sbjct: 170 VYGPREG---HKGSMASVAFHLNTQLNNGESPKLFEGSENFKRDFVYVGDVADVNLWFLE 226 Query: 233 EYNEVEPIILSVGEEDEVSIKEAAEAVVEAMDFHGEVTF----DTTKSDGQFKKTASNSK 288 N V I ++G S + A+A + A G++ + D K Q A + Sbjct: 227 --NGVSG-IFNLGTGRAESFQAVADATL-AYHKKGQIEYIPFPDKLKGRYQAFTQADLTN 282 Query: 289 LRTYLPDFRFTPFKQAVKETCAWFT 313 LR D F + V E AW Sbjct: 283 LRAAGYDKPFKTVAEGVTEYMAWLN 307 >2HUN-A nrPDB Length = 336 Score = 37.7 bits (86), Expect = 0.006, Method: Compositional matrix adjust. Identities = 75/338 (22%), Positives = 129/338 (38%), Gaps = 55/338 (16%) Query: 7 SMRILVTGGSGLVGKAIQKVVADGAGLPGEDWVFVS------------SKD--------- 45 SM++LVTGG G +G + + + DW ++ KD Sbjct: 3 SMKLLVTGGMGFIGSNFIRYILEKH----PDWEVINIDKLGYGSNPANLKDLEDDPRYTF 58 Query: 46 --ADLTDTAQTRALFEKVQPTHVIHLAAMVGGLFRNIKYNLDFWRKNVHMNDNVLHSAF- 102 D+ D + L KV V+HLAA + R+I F NV +L S Sbjct: 59 VKGDVADYELVKELVRKVD--GVVHLAAE-SHVDRSISSPEIFLHSNVIGTYTLLESIRR 115 Query: 103 EVGARKVVSCLSTCIFPD--KTTYPIDETMIHNGPPHNSNFGYSYAKRMIDVQNRAYFQQ 160 E + V + ++ D K ++ ++ ++ + P YS K D+ + + Sbjct: 116 ENPEVRFVHVSTDEVYGDILKGSFTENDRLMPSSP-------YSATKAASDMLVLGWTRT 168 Query: 161 YGCTFTAVIPTNVFGPHDNFNIEDGHVLPGLIHKVHLAKSSGSALTVWGTGNPRRQFIYS 220 Y + TN +GP+ LI K + S G + ++GTG R ++Y Sbjct: 169 YNLNASITRCTNNYGPY--------QFPEKLIPKTIIRASLGLKIPIYGTGKNVRDWLYV 220 Query: 221 LDLAQLFIWVLREYNEVEPIILSVGEEDEVSIKEAAEAVVEAMDFHGEVTFDTTKSDGQF 280 D + VL + E +S GEE + E + ++ M E+ G Sbjct: 221 EDHVRAIELVLLKGESREIYNISAGEEK--TNLEVVKIILRLMGKGEELIELVEDRPGHD 278 Query: 281 KKTASNSKLRTYLPDFRFTP---FKQAVKETCAWFTDN 315 + + +S T D ++ P F + +K+T W+ N Sbjct: 279 LRYSLDSWKITR--DLKWRPKYTFDEGIKKTIDWYLKN 314 >2X86-A nrPDB Length = 357 Score = 37.0 bits (84), Expect = 0.012, Method: Compositional matrix adjust. Identities = 74/325 (22%), Positives = 119/325 (36%), Gaps = 40/325 (12%) Query: 10 ILVTGGSGLVGKAIQKVVADGAGLPG--------EDWVFVSSKDADLTDTAQTRALFEKV 61 I+VTGG+G +G I K + D G+ + FV+ D ++ D ++ Sbjct: 49 IIVTGGAGFIGSNIVKALND-KGITDILVVDNLKDGTKFVNLVDLNIADYMDKEDFLIQI 107 Query: 62 QPTH-------VIHLAAMVGGLFRNIKYNLDFWRKNVHMNDNVLHSAFEVGARKV--VSC 112 + H A + KY +D N + +LH E R++ + Sbjct: 108 MAGEEFGDVEAIFHEGACSSTTEWDGKYMMD---NNYQYSKELLHYCLE---REIPFLYA 161 Query: 113 LSTCIFPDKTTYPIDETMIHNGPPHNSNFGYSYAKRMIDVQNRAYFQQYGCTFTAVIPTN 172 S + +T+ I+ P N FGYS K + D R + N Sbjct: 162 SSAATYGGRTSDFIESREYEK--PLNV-FGYS--KFLFDEYVRQILPEANSQIVGFRYFN 216 Query: 173 VFGPHDNFNIEDGHVLPGLIHKVHLAKSSGSALTVWGTGNPRRQFIYSLDLAQLFIWVLR 232 V+GP + G + H + S G+ N +R F+Y D+A + +W L Sbjct: 217 VYGPREG---HKGSMASVAFHLNTQLNNGESPKLFEGSENFKRDFVYVGDVADVNLWFLE 273 Query: 233 EYNEVEPIILSVGEEDEVSIKEAAEAVVEAMDFHGEVTF----DTTKSDGQFKKTASNSK 288 N V I ++G S + A+A + A G++ + D K Q A + Sbjct: 274 --NGVSG-IFNLGTGRAESFQAVADATL-AYHKKGQIEYIPFPDKLKGRYQAFTQADLTN 329 Query: 289 LRTYLPDFRFTPFKQAVKETCAWFT 313 LR D F + V E AW Sbjct: 330 LRAAGYDKPFKTVAEGVTEYMAWLN 354 >2PK3-A nrPDB Length = 321 Score = 35.8 bits (81), Expect = 0.023, Method: Compositional matrix adjust. Identities = 24/78 (30%), Positives = 39/78 (50%), Gaps = 17/78 (21%) Query: 6 GSMRILVTGGSGLVGKAI------QKVVADG------AGLPGEDWVFVSSKDADLTDTAQ 53 GSMR L+TG +G VGK + Q V G A LP + + + D+ D+ + Sbjct: 11 GSMRALITGVAGFVGKYLANHLTEQNVEVFGTSRNNEAKLPNVEMISL-----DIMDSQR 65 Query: 54 TRALFEKVQPTHVIHLAA 71 + + ++P ++ HLAA Sbjct: 66 VKKVISDIKPDYIFHLAA 83 >3SC6-A nrPDB Length = 287 Score = 35.0 bits (79), Expect = 0.049, Method: Compositional matrix adjust. Identities = 18/64 (28%), Positives = 38/64 (59%), Gaps = 6/64 (9%) Query: 9 RILVTGGSGLVGKAIQKVVADGAGLPGEDWVF-VSSKDADLTDTAQTRALFEKVQPTHVI 67 R+++TG +G +GK +Q+ + P E ++ K D+T+ +Q + + ++++P +I Sbjct: 7 RVIITGANGQLGKQLQEELN-----PEEYDIYPFDKKLLDITNISQVQQVVQEIRPHIII 61 Query: 68 HLAA 71 H AA Sbjct: 62 HCAA 65 >3ENK-A nrPDB Length = 341 Score = 34.7 bits (78), Expect = 0.055, Method: Compositional matrix adjust. Identities = 61/254 (24%), Positives = 102/254 (40%), Gaps = 42/254 (16%) Query: 10 ILVTGGSGLVGKAIQ-KVVADGAGLPGEDWVFVSSKDA--------------DLTDTAQT 54 ILVTGG+G +G +++A G + D + S ++A TD + Sbjct: 8 ILVTGGAGYIGSHTAVELLAHGYDVVIADNLVNSKREAIARIEKITGKTPAFHETDVSDE 67 Query: 55 RAL---FEKVQPTHVIHLAAMVGGLFRNIKYNLDFWRKNVHMNDNVLHSAFEVGARKVVS 111 RAL F+ T IH AA+ + ++ ++++R N+ ++L E +++V Sbjct: 68 RALARIFDAHPITAAIHFAAL-KAVGESVAKPIEYYRNNLDSLLSLLRVMRERAVKRIVF 126 Query: 112 CLSTCIFPDKTTYPIDETMIHNGPPHNSNFGYSYAKRMID--------------VQNRAY 157 S ++ PIDET P ++ Y K M + V Y Sbjct: 127 SSSATVYGVPERSPIDETF-----PLSATNPYGQTKLMAEQILRDVEAADPSWRVATLRY 181 Query: 158 FQQYGCTFTAVIPTNVFGPHDNFNIEDGHVLPGLIHKVHLAKSSGSALTVWGTGNPRRQF 217 F G + +I + G +N V G + K+ + S T GTG R + Sbjct: 182 FNPVGAHESGLIGEDPAGIPNNLMPYVAQVAVGKLEKLRVFGSDYP--TPDGTGV--RDY 237 Query: 218 IYSLDLAQLFIWVL 231 I+ +DLA+ I L Sbjct: 238 IHVVDLARGHIAAL 251 >1Z45-A nrPDB Length = 699 Score = 34.3 bits (77), Expect = 0.066, Method: Compositional matrix adjust. Identities = 61/264 (23%), Positives = 105/264 (39%), Gaps = 34/264 (12%) Query: 7 SMRILVTGGSGLVGK-AIQKVVADGAGLPGEDWVFVSSKDA-----------------DL 48 S +LVTGG+G +G + +++ +G D + S+ D+ DL Sbjct: 11 SKIVLVTGGAGYIGSHTVVELIENGYDCVVADNLSNSTYDSVARLEVLTKHHIPFYEVDL 70 Query: 49 TDTAQTRALFEKVQPTHVIHLAAMVGGLFRNIKYNLDFWRKNVHMNDNVLHSAFEVGARK 108 D +F++ + VIH A + + + + L ++ N+ +L + K Sbjct: 71 CDRKGLEKVFKEYKIDSVIHFAGL-KAVGESTQIPLRYYHNNILGTVVLLELMQQYNVSK 129 Query: 109 VVSCLSTCIFPDKTTYPIDETMIHNGPPHNSNFGYSYAKRMID-VQNRAY-FQQYGCTFT 166 V S ++ D T +P + I P Y + K I+ + N Y + F Sbjct: 130 FVFSSSATVYGDATRFP-NMIPIPEECPLGPTNPYGHTKYAIENILNDLYNSDKKSWKFA 188 Query: 167 AVIPTNVFGPHDNFNI-EDGHVLPG--LIHKVHLAKSSGSALTVWG------TGNPRRQF 217 + N G H + I ED +P L + +A L ++G G P R + Sbjct: 189 ILRYFNPIGAHPSGLIGEDPLGIPNNLLPYMAQVAVGRREKLYIFGDDYDSRDGTPIRDY 248 Query: 218 IYSLDLAQLFIWVLR---EYNEVE 238 I+ +DLA+ I L+ YNE E Sbjct: 249 IHVVDLAKGHIAALQYLEAYNENE 272 >4LIS-A nrPDB Length = 371 Score = 34.3 bits (77), Expect = 0.075, Method: Compositional matrix adjust. Identities = 39/141 (27%), Positives = 60/141 (42%), Gaps = 22/141 (15%) Query: 4 PQGSMRILVTGGSGLVGK---------AIQKVVADGAGLPGEDWV----FVSSKDADLTD 50 P GS +LVTGG+G +G + VVAD + + +S K A+ Sbjct: 2 PSGS--VLVTGGTGYIGSFTTLALLEAGYKVVVADNLYNSSAEALNRIELISGKKAEFAQ 59 Query: 51 TAQT-RALFEKVQPTH-----VIHLAAMVGGLFRNIKYNLDFWRKNVHMNDNVLHSAFEV 104 T A F+KV H VIH AA+ + + + LD++ NV+ +L S Sbjct: 60 LDVTDEAAFDKVFEAHPDIDSVIHFAAL-KAVGESGEKPLDYYHVNVYGTICLLRSMVRH 118 Query: 105 GARKVVSCLSTCIFPDKTTYP 125 +V S ++ D T +P Sbjct: 119 NVTNIVFSSSATVYGDATRFP 139 >2NM0-A nrPDB Length = 253 Score = 33.1 bits (74), Expect = 0.15, Method: Compositional matrix adjust. Identities = 22/68 (32%), Positives = 35/68 (51%), Gaps = 12/68 (17%) Query: 7 SMRILVTGGSGLVGKAIQKVVADG---------AGLPGEDWVFVSSKDADLTDTAQTRAL 57 S +LVTGG+ +G AI + AD +G P E ++ V D+TDT Q Sbjct: 21 SRSVLVTGGNRGIGLAIARAFADAGDKVAITYRSGEPPEGFLAVK---CDITDTEQVEQA 77 Query: 58 FEKVQPTH 65 +++++ TH Sbjct: 78 YKEIEETH 85 >6BI4-A nrPDB Length = 346 Score = 32.3 bits (72), Expect = 0.31, Method: Compositional matrix adjust. Identities = 40/186 (21%), Positives = 77/186 (41%), Gaps = 17/186 (9%) Query: 136 PHNSNFGYSYAKRMIDVQNRAYFQQYGCTFTAVIPTNVFGPHDNFNIEDGHVLPGLIHKV 195 P N YS +K D+ AY++ Y +N +GP+ ++P ++ Sbjct: 167 PLAPNSPYSSSKASADMIALAYYKTYQLPVIVTRCSNNYGPYQ----YPEKLIPLMVTNA 222 Query: 196 HLAKSSGSALTVWGTGNPRRQFIYSLDLAQLFIWVLREYNEVEPIILSVGEEDEVSIKEA 255 G L ++G G R +++ D VL + E + ++G +E + E Sbjct: 223 ----LEGKKLPLYGDGLNVRDWLHVTDHCSAIDVVLHKGRVGE--VYNIGGNNEKTNVEV 276 Query: 256 AEAVVEAMDFHGEVTFDTTKSDGQFKKTASNS-KLRTYLPDFRFTP---FKQAVKETCAW 311 E ++ + + T G ++ A N+ K++ +F + P F+Q ++ET W Sbjct: 277 VEQIITLLGKTKKDIEYVTDRLGHDRRYAINAEKMKN---EFDWEPKYTFEQGLQETVQW 333 Query: 312 FTDNYE 317 + N E Sbjct: 334 YEKNEE 339 >2V0O-A nrPDB Length = 276 Score = 32.0 bits (71), Expect = 0.42, Method: Compositional matrix adjust. Identities = 16/58 (27%), Positives = 29/58 (50%), Gaps = 11/58 (18%) Query: 45 DADLTDTAQTRALFEKVQPTHVIHLAAMVGGLFRNIKYNLDFWRKNVHMNDNVLHSAF 102 + +T+TAQ F+ ++ TH+IH+ ++G L I K +H+ +H F Sbjct: 194 EQKMTETAQK---FQDIEETHLIHIKEIIGSLSNAI--------KEIHLQIGQVHEEF 240 >4KTT-E nrPDB Length = 327 Score = 31.2 bits (69), Expect = 0.59, Method: Compositional matrix adjust. Identities = 21/69 (30%), Positives = 32/69 (46%), Gaps = 9/69 (13%) Query: 9 RILVTGGSGLVGKAIQKVV------ADGAGLPGEDWVFVSSKDADLTDTAQTRALFEKVQ 62 R+LVTG +GL+G+A+ K A G G F + +L D+ + Q Sbjct: 23 RVLVTGATGLLGRAVHKEFQQNNWHAVGCGFRRARPKF---EQVNLLDSNAVHHIIHDFQ 79 Query: 63 PTHVIHLAA 71 P ++H AA Sbjct: 80 PHVIVHCAA 88 >6CCF-A nrPDB Length = 290 Score = 29.6 bits (65), Expect = 1.7, Method: Compositional matrix adjust. Identities = 22/69 (31%), Positives = 34/69 (49%), Gaps = 4/69 (5%) Query: 201 SGSALTVWGTGNPRRQFIY-SLDLAQLFIWVLREYNEVEPIILSVGEEDEVSIKEAAEAV 259 SG AL VW TG F+Y FI L + EP++ EE E+S +E + + Sbjct: 209 SGKALDVWATGVTLYCFVYGKCPFIDDFILALHRKIKNEPVVFP--EEPEIS-EELKDLI 265 Query: 260 VEAMDFHGE 268 ++ +D + E Sbjct: 266 LKMLDKNPE 274 >3BRE-A nrPDB Length = 358 Score = 28.5 bits (62), Expect = 4.2, Method: Compositional matrix adjust. Identities = 19/75 (25%), Positives = 39/75 (52%), Gaps = 11/75 (14%) Query: 1 MGEP-QGSMRILVTGGSGLVGKAIQKVVADGAGLPGEDWVFVSSKDADLTDTAQTRALFE 59 +G P G++ +L+ ++G+A+++ +A AG+ D+ F S D Q A+ Sbjct: 11 LGAPLDGAVMVLLVDDQAMIGEAVRRSLASEAGI---DFHFCS-------DPQQAVAVAN 60 Query: 60 KVQPTHVIHLAAMVG 74 +++PT ++ M G Sbjct: 61 QIKPTVILQDLVMPG 75 >3RWB-A nrPDB Length = 247 Score = 28.5 bits (62), Expect = 4.5, Method: Compositional matrix adjust. Identities = 32/110 (29%), Positives = 47/110 (42%), Gaps = 34/110 (30%) Query: 11 LVTGGSGLVGKAIQ-KVVADGAGLPGEDW---------VFVSSKD----ADLTDTAQTRA 56 LVTG + +GKAI ++ ADGA + D + K AD++D +A Sbjct: 10 LVTGAAQGIGKAIAARLAADGATVIVSDINAEGAKAAAASIGKKARAIAADISDPGSVKA 69 Query: 57 LFEKVQPTHVIHLAAMVGG---LFRNIK---------YNLDFWRKNVHMN 94 LF ++Q A+ GG L N +LD WRK + +N Sbjct: 70 LFAEIQ--------ALTGGIDILVNNASIVPFVAWDDVDLDHWRKIIDVN 111 >6GER-A nrPDB Length = 509 Score = 28.1 bits (61), Expect = 5.7, Method: Compositional matrix adjust. Identities = 12/32 (37%), Positives = 20/32 (62%), Gaps = 3/32 (9%) Query: 133 NGPPHNSNFGYSYAK---RMIDVQNRAYFQQY 161 NGPP + FG++Y + +++ QN A FQ + Sbjct: 404 NGPPEHKLFGFTYLRLSNELLEGQNYATFQTF 435 >5NUE-A nrPDB Length = 332 Score = 27.7 bits (60), Expect = 6.3, Method: Compositional matrix adjust. Identities = 31/107 (28%), Positives = 50/107 (46%), Gaps = 22/107 (20%) Query: 8 MRILVTGGSGLVGKAIQKVVADGAGLPGEDWVFVSSKD------------ADLTDTA--- 52 +R+LVTG +G +G A+ ++A G L + V + D +L D A Sbjct: 6 VRVLVTGAAGQIGYALVPMIARGIMLGADQPVILHMLDIPPAAEALNGVKMELIDAAFPL 65 Query: 53 --QTRALFEKVQPTHVIHLAAMVGGLFRNIKYNLDFWRKNVHMNDNV 97 A + V+ +++A MVGG R K ++ RK+V M+ NV Sbjct: 66 LKGVVATTDAVEGCTGVNVAVMVGGFPR--KEGME--RKDV-MSKNV 107 >3SS3-A nrPDB Length = 479 Score = 27.7 bits (60), Expect = 6.6, Method: Compositional matrix adjust. Identities = 15/48 (31%), Positives = 24/48 (50%), Gaps = 3/48 (6%) Query: 81 KYNLDFWRKNVHMNDNVLHSAFEVGARKVVSCLSTCIFPDKTTYPIDE 128 K++ D W +V D HS +G KV CL +C+ P K +++ Sbjct: 136 KFSPDLWGVSVCTVDGQRHS---IGDTKVPFCLQSCVKPLKYAIAVND 180 >5W2J-A nrPDB Length = 411 Score = 27.7 bits (60), Expect = 7.8, Method: Compositional matrix adjust. Identities = 15/48 (31%), Positives = 24/48 (50%), Gaps = 3/48 (6%) Query: 81 KYNLDFWRKNVHMNDNVLHSAFEVGARKVVSCLSTCIFPDKTTYPIDE 128 K++ D W +V D HS +G KV CL +C+ P K +++ Sbjct: 120 KFSPDLWGVSVCTVDGQRHS---IGDTKVPFCLQSCVKPLKYAIAVND 164 >5WJ6-A nrPDB Length = 539 Score = 27.7 bits (60), Expect = 7.9, Method: Compositional matrix adjust. Identities = 15/48 (31%), Positives = 23/48 (47%), Gaps = 3/48 (6%) Query: 81 KYNLDFWRKNVHMNDNVLHSAFEVGARKVVSCLSTCIFPDKTTYPIDE 128 K++ D W +V D HS G KV CL +C+ P K +++ Sbjct: 196 KFSPDLWGVSVCTADGQRHS---TGDTKVPFCLQSCVKPLKYAIAVND 240 >4BQM-A nrPDB Length = 349 Score = 27.3 bits (59), Expect = 8.3, Method: Compositional matrix adjust. Identities = 27/93 (29%), Positives = 40/93 (43%), Gaps = 9/93 (9%) Query: 35 GEDWVFVSSKDADLTD-TAQTRALFEKVQPTHVIHLAAMVGGLFRNIKYNLDFWRKNVHM 93 G + ++ S D + T +FE V+ +AA + L K N D W ++ Sbjct: 14 GTENLYFQSMIPDFEEFTGHVDRIFEDVKELTGGKVAAYIPQL---AKSNPDLWGVSLCT 70 Query: 94 NDNVLHSAFEVGARKVVSCLSTCIFPDKTTYPI 126 D HS VG K+ CL +C+ P TY I Sbjct: 71 VDGQRHS---VGHTKIPFCLQSCVKP--LTYAI 98 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 4BKP-A nrPDB 410 e-115 6AQY-A nrPDB 367 e-102 1GFS-A nrPDB 332 2e-91 1BXK-A nrPDB 307 3e-84 1KEU-A nrPDB 298 2e-81 1R66-A nrPDB 289 8e-79 2Q1W-A nrPDB 239 1e-63 3RUE-A nrPDB 232 1e-61 4WOK-A nrPDB 225 2e-59 6BWL-A nrPDB 223 7e-59 1OC2-A nrPDB 223 1e-58 3M2P-A nrPDB 217 4e-57 1I3M-A nrPDB 213 9e-56 4WKG-A nrPDB 148 4e-36 1VL0-A nrPDB 115 3e-26 Sequences not found previously or not previously below threshold: 2HUN-A nrPDB 228 2e-60 6BI4-A nrPDB 222 1e-58 1UDA-A nrPDB 187 7e-48 1Z45-A nrPDB 183 1e-46 2C20-A nrPDB 169 1e-42 4LIS-A nrPDB 167 6e-42 1GY8-A nrPDB 161 4e-40 3ENK-A nrPDB 158 3e-39 2PZM-A nrPDB 154 3e-38 2C54-A nrPDB 151 5e-37 2Q1T-A nrPDB 145 2e-35 1ORR-A nrPDB 142 2e-34 2PK3-A nrPDB 140 8e-34 1EQ2-A nrPDB 114 4e-26 2X86-A nrPDB 113 1e-25 4EJ0-A nrPDB 106 2e-23 1DB3-A nrPDB 103 1e-22 3SXP-A nrPDB 94 6e-20 3SC6-A nrPDB 93 1e-19 3WMX-A nrPDB 91 6e-19 4WPG-A nrPDB 88 4e-18 4J2O-A nrPDB 88 6e-18 6GPK-A nrPDB 88 6e-18 2Z95-A nrPDB 88 7e-18 1N7G-A nrPDB 87 8e-18 5UZH-A nrPDB 87 1e-17 1WVG-A nrPDB 86 1e-17 1RPN-A nrPDB 84 5e-17 4R1T-A nrPDB 82 4e-16 1RKX-A nrPDB 81 5e-16 4G5H-A nrPDB 81 6e-16 4KTT-E nrPDB 81 7e-16 5B6K-A nrPDB 78 6e-15 2GN9-A nrPDB 71 7e-13 5U9C-A nrPDB 69 2e-12 4R1U-A nrPDB 69 2e-12 2P4H-X nrPDB 69 2e-12 2GGS-A nrPDB 68 4e-12 3HFS-A nrPDB 67 9e-12 2NNL-D nrPDB 67 9e-12 3RFT-A nrPDB 66 3e-11 1KC3-A nrPDB 64 9e-11 4PVC-A nrPDB 61 6e-10 1ZZE-A nrPDB 56 2e-08 4QUK-A nrPDB 53 1e-07 5GUP-L nrPDB 46 2e-05 5YWN-A nrPDB 45 4e-05 2NM0-A nrPDB 42 3e-04 4B4O-A nrPDB 42 4e-04 1QYC-A nrPDB 41 0.001 2V6G-A nrPDB 40 0.002 4AVY-A nrPDB 39 0.002 3PVZ-A nrPDB 39 0.002 2Q4B-A nrPDB 39 0.003 1MLD-A nrPDB 38 0.004 4WLE-A nrPDB 38 0.004 5OVL-A nrPDB 36 0.033 6GCS-E nrPDB 35 0.038 5OVJ-A nrPDB 35 0.039 1QYD-A nrPDB 34 0.087 6G2J-P nrPDB 34 0.12 1OOE-A nrPDB 34 0.12 5DBI-A nrPDB 33 0.14 2ZCU-A nrPDB 33 0.17 4I1I-A nrPDB 32 0.36 5NUE-A nrPDB 31 0.56 4J6F-A nrPDB 31 0.75 5F5N-A nrPDB 31 0.86 2EW8-A nrPDB 31 1.1 1UZM-A nrPDB 31 1.1 5KT0-A nrPDB 30 1.1 2QYS-A nrPDB 30 1.8 3RWB-A nrPDB 29 1.9 4UFC-A nrPDB 29 2.1 3UW3-A nrPDB 29 2.2 3WSV-A nrPDB 29 2.2 1BDB-A nrPDB 29 2.5 4TVO-A nrPDB 29 2.9 4FK8-A nrPDB 29 2.9 3PXX-A nrPDB 29 3.0 2YV3-A nrPDB 29 3.5 4UUP-A nrPDB 29 3.9 4BL3-A nrPDB 29 4.2 4IIV-A nrPDB 28 4.9 4UUM-A nrPDB 28 5.1 4E0B-A nrPDB 28 5.1 4A10-A nrPDB 28 5.9 3SLK-A nrPDB 28 6.0 2PH3-A nrPDB 28 6.4 2LDB-A nrPDB 27 9.4 >4BKP-A nrPDB Length = 336 Score = 410 bits (1054), Expect = e-115, Method: Composition-based stats. Identities = 315/315 (100%), Positives = 315/315 (100%) Query: 7 SMRILVTGGSGLVGKAIQKVVADGAGLPGEDWVFVSSKDADLTDTAQTRALFEKVQPTHV 66 SMRILVTGGSGLVGKAIQKVVADGAGLPGEDWVFVSSKDADLTDTAQTRALFEKVQPTHV Sbjct: 22 SMRILVTGGSGLVGKAIQKVVADGAGLPGEDWVFVSSKDADLTDTAQTRALFEKVQPTHV 81 Query: 67 IHLAAMVGGLFRNIKYNLDFWRKNVHMNDNVLHSAFEVGARKVVSCLSTCIFPDKTTYPI 126 IHLAAMVGGLFRNIKYNLDFWRKNVHMNDNVLHSAFEVGARKVVSCLSTCIFPDKTTYPI Sbjct: 82 IHLAAMVGGLFRNIKYNLDFWRKNVHMNDNVLHSAFEVGARKVVSCLSTCIFPDKTTYPI 141 Query: 127 DETMIHNGPPHNSNFGYSYAKRMIDVQNRAYFQQYGCTFTAVIPTNVFGPHDNFNIEDGH 186 DETMIHNGPPHNSNFGYSYAKRMIDVQNRAYFQQYGCTFTAVIPTNVFGPHDNFNIEDGH Sbjct: 142 DETMIHNGPPHNSNFGYSYAKRMIDVQNRAYFQQYGCTFTAVIPTNVFGPHDNFNIEDGH 201 Query: 187 VLPGLIHKVHLAKSSGSALTVWGTGNPRRQFIYSLDLAQLFIWVLREYNEVEPIILSVGE 246 VLPGLIHKVHLAKSSGSALTVWGTGNPRRQFIYSLDLAQLFIWVLREYNEVEPIILSVGE Sbjct: 202 VLPGLIHKVHLAKSSGSALTVWGTGNPRRQFIYSLDLAQLFIWVLREYNEVEPIILSVGE 261 Query: 247 EDEVSIKEAAEAVVEAMDFHGEVTFDTTKSDGQFKKTASNSKLRTYLPDFRFTPFKQAVK 306 EDEVSIKEAAEAVVEAMDFHGEVTFDTTKSDGQFKKTASNSKLRTYLPDFRFTPFKQAVK Sbjct: 262 EDEVSIKEAAEAVVEAMDFHGEVTFDTTKSDGQFKKTASNSKLRTYLPDFRFTPFKQAVK 321 Query: 307 ETCAWFTDNYEQARK 321 ETCAWFTDNYEQARK Sbjct: 322 ETCAWFTDNYEQARK 336 >6AQY-A nrPDB Length = 341 Score = 367 bits (941), Expect = e-102, Method: Composition-based stats. Identities = 166/317 (52%), Positives = 226/317 (71%), Gaps = 7/317 (2%) Query: 10 ILVTGGSGLVGKAIQKVVADGAGLPGEDWVFVSSKDADLTDTAQTRALFEKVQPTHVIHL 69 ILVTGG+GL GKA++ +V + G+ WVF+ SKD DL D + FEK +PT+VIHL Sbjct: 27 ILVTGGTGLFGKAVEHIVK-KEQIKGK-WVFLGSKDGDLRDADACKQPFEKYRPTYVIHL 84 Query: 70 AAMVGGLFRNIKYNLDFWRKNVHMNDNVLHSAFEVGARKVVSCLSTCIFPDKTTYPIDET 129 AA VGGLF+N+ + + FW NV+MN+N+L ++ G +K +SCLSTC+FPDK YPI E Sbjct: 85 AAFVGGLFKNMNFKVSFWLDNVNMNNNILTCCYDFGVKKTISCLSTCVFPDKIEYPITEE 144 Query: 130 MIHNGPPHNSNFGYSYAKRMIDVQNRAYFQQ-----YGCTFTAVIPTNVFGPHDNFNIED 184 +H GPPH SN Y+YAKRM+D+ R Y ++ C FT+VIPTN+FGPHDNFN+E Sbjct: 145 KLHEGPPHFSNNAYAYAKRMLDMLGRWYNEKAVNEGKSCLFTSVIPTNLFGPHDNFNVEA 204 Query: 185 GHVLPGLIHKVHLAKSSGSALTVWGTGNPRRQFIYSLDLAQLFIWVLREYNEVEPIILSV 244 GHVLPGL+HK + A+ +G+ V+G+G P RQF+YS D A++ +W + Y EPI+L V Sbjct: 205 GHVLPGLMHKCYKAQQNGTDFVVFGSGKPLRQFLYSHDAARMLLWTMFNYQSEEPIMLCV 264 Query: 245 GEEDEVSIKEAAEAVVEAMDFHGEVTFDTTKSDGQFKKTASNSKLRTYLPDFRFTPFKQA 304 EEDE SI + A+ + +A +F G + FDT+K+DGQ+KKT+SN+K P F++TPF+QA Sbjct: 265 SEEDEKSIGQVAQTIKDAFNFTGNMVFDTSKADGQYKKTSSNAKFLRLNPTFQYTPFEQA 324 Query: 305 VKETCAWFTDNYEQARK 321 +KET WF +NYE ARK Sbjct: 325 IKETVQWFLENYETARK 341 >1GFS-A nrPDB Length = 321 Score = 332 bits (850), Expect = 2e-91, Method: Composition-based stats. Identities = 91/320 (28%), Positives = 166/320 (51%), Gaps = 12/320 (3%) Query: 9 RILVTGGSGLVGKAIQKVVADGAGLPGEDWVFVSSKDADLTDTAQTRALFEKVQPTHVIH 68 R+ + G G+VG AI++ + + + V + + +L D+ F + V Sbjct: 5 RVFIAGHRGMVGSAIRRQLEQRGDV---ELVLRTRDELNLLDSRAVHDFFASERIDQVYL 61 Query: 69 LAAMVGGLFRNIKYNLDFWRKNVHMNDNVLHSAFEVGARKVVSCLSTCIFPDKTTYPIDE 128 AA VGG+ N Y DF +N+ + N++H+A + K++ S+CI+P P+ E Sbjct: 62 AAAKVGGIVANNTYPADFIYQNMMIESNIIHAAHQNDVNKLLFLGSSCIYPKLAKQPMAE 121 Query: 129 TMIHNGPPHNSNFGYSYAKRMIDVQNRAYFQQYGCTFTAVIPTNVFGPHDNFNIEDGHVL 188 + + G +N Y+ AK +Y +QYG + +V+PTN++GPHDNF+ + HV+ Sbjct: 122 SELLQGTLEPTNEPYAIAKIAGIKLCESYNRQYGRDYRSVMPTNLYGPHDNFHPSNSHVI 181 Query: 189 PGLIHKVHLAKSSGSA-LTVWGTGNPRRQFIYSLDLAQLFIWVLREYNEV-----EPII- 241 P L+ + H A + + + VWG+G P R+F++ D+A I V+ +EV +P++ Sbjct: 182 PALLRRFHEATAQNAPDVVVWGSGTPMREFLHVDDMAAASIHVMELAHEVWLENTQPMLS 241 Query: 242 -LSVGEEDEVSIKEAAEAVVEAMDFHGEVTFDTTKSDGQFKKTASNSKLRTYLPDFRFTP 300 ++VG + +I+E A+ + + + + G V FD +K DG +K ++L L + Sbjct: 242 HINVGTGVDCTIRELAQTIAKVVGYKGRVVFDASKPDGTPRKLLDVTRLHQ-LGWYHEIS 300 Query: 301 FKQAVKETCAWFTDNYEQAR 320 + + T WF +N ++ R Sbjct: 301 LEAGLASTYQWFLENQDRFR 320 >1BXK-A nrPDB Length = 355 Score = 307 bits (787), Expect = 3e-84, Method: Composition-based stats. Identities = 72/343 (20%), Positives = 124/343 (36%), Gaps = 47/343 (13%) Query: 9 RILVTGGSGLVGKAIQK----------VVADGAGLPGEDWVFVS--------SKDADLTD 50 +IL+TGG+G +G A+ + VV D G + D+ D Sbjct: 3 KILITGGAGFIGSALVRYIINETSDAVVVVDKLTYAGNLMSLAPVAQSERFAFEKVDICD 62 Query: 51 TAQTRALFEKVQPTHVIHLAAMVGGLFRNIKYNLDFWRKNVHMNDNVLHSAFEVGARKVV 110 A+ +F + QP V+HLAA + R+I F N+ +L +A Sbjct: 63 RAELARVFTEHQPDCVMHLAAE-SHVDRSIDGPAAFIETNIVGTYTLLEAARAYWNALTE 121 Query: 111 SCLSTCIFPDKTTYPI------DETMIHNGPPHNSNFGYSYAKRMIDVQNRAYFQQYGCT 164 S F +T + + P+ + YS +K D RA+ + YG Sbjct: 122 DKKSAFRFHHISTDEVYGDLHSTDDFFTETTPYAPSSPYSASKASSDHLVRAWLRTYGLP 181 Query: 165 FTAVIPTNVFGPHDNFNIEDGHVLPGLIHKVHLAKSSGSALTVWGTGNPRRQFIYSLDLA 224 +N +GP+ H LI + L +G +L V+G G R ++Y D A Sbjct: 182 TLITNCSNNYGPY--------HFPEKLIPLMILNALAGKSLPVYGNGQQIRDWLYVEDHA 233 Query: 225 QLFIWVLREYNEVEPIILSVGEEDEVSIKEAAEAVVEAMD------------FHGEVTFD 272 + V E ++G +E + E + E ++ + +TF Sbjct: 234 RALYCVATTGKVGE--TYNIGGHNERKNLDVVETICELLEELAPNKPHGVAHYRDLITFV 291 Query: 273 TTKSDGQFKKTASNSKLRTYLPDFRFTPFKQAVKETCAWFTDN 315 + + SK+ L F+ +++T W+ N Sbjct: 292 ADRPGHDLRYAIDASKIARELGCVPQETFESGMRKTVQWYLAN 334 >1KEU-A nrPDB Length = 361 Score = 298 bits (763), Expect = 2e-81, Method: Composition-based stats. Identities = 72/348 (20%), Positives = 132/348 (37%), Gaps = 51/348 (14%) Query: 8 MRILVTGGSGLVGKAIQK----------VVADGAGLPG--------EDWVFVSSKDADLT 49 M+IL+TGG+G +G A+ + V D G + + + AD+ Sbjct: 1 MKILITGGAGFIGSAVVRHIIKNTQDTVVNIDKLTYAGNLESLSDISESNRYNFEHADIC 60 Query: 50 DTAQTRALFEKVQPTHVIHLAAMVGGLFRNIKYNLDFWRKNVHMNDNVLHSAFEVGAR-- 107 D+A+ +FE+ QP V+HLAA + R+I F N+ +L A + + Sbjct: 61 DSAEITRIFEQYQPDAVMHLAAE-SHVDRSITGPAAFIETNIVGTYALLEVARKYWSALG 119 Query: 108 -------KVVSCLSTCIF-----PDKTTYPIDETMIHNGPPHNSNFGYSYAKRMIDVQNR 155 + + ++ PD+ + + + + YS +K D R Sbjct: 120 EDKKNNFRFHHISTDEVYGDLPHPDEVENSVTLPLFTETTAYAPSSPYSASKASSDHLVR 179 Query: 156 AYFQQYGCTFTAVIPTNVFGPHDNFNIEDGHVLPGLIHKVHLAKSSGSALTVWGTGNPRR 215 A+ + YG +N +GP+ H LI V L G L ++G G+ R Sbjct: 180 AWRRTYGLPTIVTNCSNNYGPY--------HFPEKLIPLVILNALEGKPLPIYGKGDQIR 231 Query: 216 QFIYSLDLAQLFIWVLREYNEVEPIILSVGEEDEVSIKEAA--------EAVVEAMDFHG 267 ++Y D A+ V+ E E ++G +E + E V +A + Sbjct: 232 DWLYVEDHARALHMVVTEGKAGE--TYNIGGHNEKKNLDVVFTICDLLDEIVPKATSYRE 289 Query: 268 EVTFDTTKSDGQFKKTASNSKLRTYLPDFRFTPFKQAVKETCAWFTDN 315 ++T+ + + K+ L F+ +++T W+ N Sbjct: 290 QITYVADRPGHDRRYAIDAGKISRELGWKPLETFESGIRKTVEWYLAN 337 >1R66-A nrPDB Length = 337 Score = 289 bits (740), Expect = 8e-79, Method: Composition-based stats. Identities = 67/329 (20%), Positives = 118/329 (35%), Gaps = 36/329 (10%) Query: 8 MRILVTGGSGLVGKAIQKVVADGA--GLPGEDWVFVSSK------------DADLT---- 49 MR+LVTGG+G +G + + GA +P ++ + + S DAD Sbjct: 1 MRLLVTGGAGFIGSHFVRQLLAGAYPDVPADEVIVLDSLTYAGNRANLAPVDADPRLRFV 60 Query: 50 --DTAQTRALFEKVQPTHVIHLAAMVGGLFRNIKYNLDFWRKNVHMNDNVLHSAFEVGAR 107 D L +++ I A + R+I F NV +L A + G Sbjct: 61 HGDIRDAGLLARELRGVDAIVHFAAESHVDRSIAGASVFTETNVQGTQTLLQCAVDAGVG 120 Query: 108 KVVSCLSTCIFPDKTTYPIDETMIHNGPPHNSNFGYSYAKRMIDVQNRAYFQQYGCTFTA 167 +VV + D+ ID P N Y+ +K D+ RAY + YG Sbjct: 121 RVVHVST-----DEVYGSIDSGSWTESSPLEPNSPYAASKAGSDLVARAYHRTYGLDVRI 175 Query: 168 VIPTNVFGPHDNFNIEDGHVLPGLIHKVHLAKSSGSALTVWGTGNPRRQFIYSLDLAQLF 227 N +GP+ + LI G L ++G G R+++++ D + Sbjct: 176 TRCCNNYGPYQHPE--------KLIPLFVTNLLDGGTLPLYGDGANVREWVHTDDHCRGI 227 Query: 228 IWVLREYNEVEPIILSVGEEDEVSIKEAAEAVVEAMDFHGEVTFD-TTKSDGQFKKTASN 286 VL E I +G E++ +E +++++ + + + Sbjct: 228 ALVLAGGRAGE--IYHIGGGLELTNRELTGILLDSLGADWSSVRKVADRKGHDLRYSLDG 285 Query: 287 SKLRTYLPDFRFTPFKQAVKETCAWFTDN 315 K+ L F + T W+ +N Sbjct: 286 GKIERELGYRPQVSFADGLARTVRWYREN 314 >2Q1W-A nrPDB Length = 333 Score = 239 bits (610), Expect = 1e-63, Method: Composition-based stats. Identities = 74/332 (22%), Positives = 121/332 (36%), Gaps = 51/332 (15%) Query: 4 PQGS--MRILVTGGSGLVGKAIQKVVADGAG-LPGEDWVFVSSKD------------ADL 48 P+GS ++ +TG G +G I +++ + + G D ++ + Sbjct: 16 PRGSHMKKVFITGICGQIGSHIAELLLERGDKVVGIDNFATGRREHLKDHPNLTFVEGSI 75 Query: 49 TDTAQTRALFEKVQPTHVIHLAAMVGGLFRNIKYNLDFWR----KNVHMNDNVLHSAFEV 104 D A L +QP V+H AA + D W N NV+ +A + Sbjct: 76 ADHALVNQLIGDLQPDAVVHTAASYK--------DPDDWYNDTLTNCVGGSNVVQAAKKN 127 Query: 105 GARKVVSCLSTCIFPDKTTYPIDETMIHNGPPHNSNFGYSYAKRMIDVQNRAYFQQYGCT 164 + V + + K PI + + + P + +N Y+ +K + Y + G Sbjct: 128 NVGRFVYFQTALCYGVK---PIQQPVRLDHPRNPANSSYAISKSANE----DYLEYSGLD 180 Query: 165 FTAVIPTNVFGPHDNFNIEDGHVLPGLIHKVHLAKSSGSALTVWGTGNPRRQFIYSLDLA 224 F NV GP N+ LP ++ S G V RR F++ DLA Sbjct: 181 FVTFRLANVVGPR---NVSGP--LPIFFQRL----SEGKKCFVT---KARRDFVFVKDLA 228 Query: 225 QLFIWVLREYNEVEPIILSVGEEDEVSIKEAAEAVVEAMDF--HGEVTFDTTKSDGQFKK 282 + +R + V +V+IKE +AVVEAM + E D Sbjct: 229 RA---TVRAVDGVGHGAYHFSSGTDVAIKELYDAVVEAMALPSYPEPEIRELGPDDAPSI 285 Query: 283 TASNSKLRTYLPDFRFTPFKQAVKETCAWFTD 314 S+ FTP K+ V A+F + Sbjct: 286 LLDPSRTIQDFGKIEFTPLKETVAAAVAYFRE 317 >3RUE-A nrPDB Length = 351 Score = 232 bits (592), Expect = 1e-61, Method: Composition-based stats. Identities = 60/329 (18%), Positives = 116/329 (35%), Gaps = 39/329 (11%) Query: 11 LVTGGSGLVGKAIQKVVADGAGLPG----------------------EDWVFVSSKDADL 48 L+TG +G +G + + + + E W + D+ Sbjct: 29 LITGVAGFIGSNLLEKLLKLNQVVIGLDNFSTGHQYNLDEVKTLVSTEQWSRFCFIEGDI 88 Query: 49 TDTAQTRALFEKVQPTHVIHLAAMVGGLFRNIKYNLDFWRKNVHMNDNVLHSAFEVGARK 108 D + + V HV+H AA+ G + R+I + N+ N+LH+A + Sbjct: 89 RDLTTCEQVMKGV--DHVLHQAAL-GSVPRSIVDPITTNATNITGFLNILHAAKNAQVQS 145 Query: 109 VVSCLSTCIFPDKTTYPIDETMIHNGPPHNSNFGYSYAKRMIDVQNRAYFQQYGCTFTAV 168 S+ + D P E I N Y+ K + ++ + Y + YG + Sbjct: 146 FTYAASSSTYGDHPALPKVEENI-----GNPLSPYAVTKYVNEIYAQVYARTYGFKTIGL 200 Query: 169 IPTNVFGPHDNFNIEDGHVLPGLIHKVHLAKSSGSALTVWGTGNPRRQFIYSLDLAQLFI 228 NVFG + N V+P K A G + + G G R F Y ++ Q+ I Sbjct: 201 RYFNVFGRRQDPNGAYAAVIP----KWTAAMLKGDDVYINGDGETSRDFCYIDNVIQMNI 256 Query: 229 WVLREYNEVEPIILSVGEEDEVSIKEAAEAVVEAMDFHGE-----VTFDTTKSDGQFKKT 283 + + I +V D ++ E + + + ++ + + +S Sbjct: 257 LSALAKDSAKDNIYNVAVGDRTTLNELSGYIYDELNLIHHIDKLSIKYREFRSGDVRHSQ 316 Query: 284 ASNSKLRTYLPDFRFTPFKQAVKETCAWF 312 A +K L ++ ++ + W+ Sbjct: 317 ADVTKAIDLLKYRPNIKIREGLRLSMPWY 345 >2HUN-A nrPDB Length = 336 Score = 228 bits (582), Expect = 2e-60, Method: Composition-based stats. Identities = 67/334 (20%), Positives = 118/334 (35%), Gaps = 47/334 (14%) Query: 7 SMRILVTGGSGLVGKAIQKVVADGAGLPGEDWVFVS-----------------------S 43 SM++LVTGG G +G + + + DW ++ Sbjct: 3 SMKLLVTGGMGFIGSNFIRYILE----KHPDWEVINIDKLGYGSNPANLKDLEDDPRYTF 58 Query: 44 KDADLTDTAQTRALFEKVQPTHVIHLAAMVGGLFRNIKYNLDFWRKNVHMNDNVLHSAF- 102 D+ D + L KV V+HLAA + R+I F NV +L S Sbjct: 59 VKGDVADYELVKELVRKVDG--VVHLAAE-SHVDRSISSPEIFLHSNVIGTYTLLESIRR 115 Query: 103 EVGARKVVSCLSTCIFPDKTTYPIDETMIHNGPPHNSNFGYSYAKRMIDVQNRAYFQQYG 162 E + V + ++ D I + + YS K D+ + + Y Sbjct: 116 ENPEVRFVHVSTDEVYGD-----ILKGSFTENDRLMPSSPYSATKAASDMLVLGWTRTYN 170 Query: 163 CTFTAVIPTNVFGPHDNFNIEDGHVLPGLIHKVHLAKSSGSALTVWGTGNPRRQFIYSLD 222 + TN +GP+ LI K + S G + ++GTG R ++Y D Sbjct: 171 LNASITRCTNNYGPYQ--------FPEKLIPKTIIRASLGLKIPIYGTGKNVRDWLYVED 222 Query: 223 LAQLFIWVLREYNEVEPIILSVGEEDEVSIKEAAEAVVEAMDFHGE-VTFDTTKSDGQFK 281 + VL + E I ++ +E + E + ++ M E + + + Sbjct: 223 HVRAIELVLLKGESRE--IYNISAGEEKTNLEVVKIILRLMGKGEELIELVEDRPGHDLR 280 Query: 282 KTASNSKLRTYLPDFRFTPFKQAVKETCAWFTDN 315 + + K+ L F + +K+T W+ N Sbjct: 281 YSLDSWKITRDLKWRPKYTFDEGIKKTIDWYLKN 314 >4WOK-A nrPDB Length = 336 Score = 225 bits (573), Expect = 2e-59, Method: Composition-based stats. Identities = 63/321 (19%), Positives = 114/321 (35%), Gaps = 27/321 (8%) Query: 10 ILVTGGSGLVGKAIQKVVADGAGLPGEDWVFVSSK-----------DADLTDTAQTRALF 58 +LV GG+G +G K++A G G + +S+ + D+ D A+ Sbjct: 14 VLVVGGAGFIGSHTAKLLA-GQGYAPVVYDNLSTGHQSAVRWGDFVEGDILDQARLVETM 72 Query: 59 EKVQPTHVIHLAAMVGGLFRNIKYNLDFWRKNVHMNDNVLHSAFEVGARKVVSCLSTCIF 118 EK P VIH AA + +++ ++R NV ++L + + V+ S + Sbjct: 73 EKYAPVAVIHFAAS-AYVGESVEDPAKYYRNNVGGTQSLLDACRLTRTQNVIFSSSCATY 131 Query: 119 PDKTTYPIDETMIHNGPPHNSNFGYSYAKRMIDVQNRAYFQQYGCTFTAVIPTNVFGPHD 178 + PI E N Y K + + Y YG + A+ N G Sbjct: 132 GVPSRLPIGEGEAQ-----NPINPYGRTKLIAEHMLADYAVAYGLRYVALRYFNASGADI 186 Query: 179 NFNIEDGH-VLPGLIHKVHLAKSSG-SALTVWG------TGNPRRQFIYSLDLAQLFIWV 230 + + + H LI + +A + L V+G G R +I+ DLA+ + Sbjct: 187 DGELGEKHDPETHLIPRAMMAAAGRLDVLEVYGDDYETPDGTCIRDYIHVTDLARAHVLA 246 Query: 231 LREYNEVEPI-ILSVGEEDEVSIKEAAEAVVEAMDFHGEVTFDTTKSDGQFKKTASNSKL 289 + E +++G SI+E +++ V ++ A + Sbjct: 247 VEHLKEAGGNLAVNLGTGRGTSIREIVQSIGRLTGRSVPVAMRARRAGDPPALYADPALA 306 Query: 290 RTYLPDFRFTPFKQAVKETCA 310 L + T A Sbjct: 307 AEKLGFHTVYSDLDTIIRTAA 327 >6BWL-A nrPDB Length = 328 Score = 223 bits (569), Expect = 7e-59, Method: Composition-based stats. Identities = 69/320 (21%), Positives = 125/320 (39%), Gaps = 28/320 (8%) Query: 8 MRILVTGGSGLVGKAIQKVVADGAGLPGEDWVF---VSSKDADLTDTAQTRALFEKVQPT 64 M+ILVTGG+G +G+ + K + E W+ +S A++T+ A L + +Q Sbjct: 1 MKILVTGGAGFIGRWVVKRLLQD---KHEVWILDNLANSTTANITEFAHDLNLKQCIQGD 57 Query: 65 HVIHLAAMVGGLFRNIKYNLDF-WRKNVHMNDNV--LHSAFEVGARKVVSCLSTCIFPDK 121 I +V LF N ++L + ++++ D++ + FE + L C+ D Sbjct: 58 --IKDKKLVAQLFENNSFDLCYHLAASINVQDSIDDARATFENDTIGTFNLLEQCLNYDV 115 Query: 122 TTYPIDETMIHNGP----------PHNSNFGYSYAKRMIDVQNRAYFQQYGCTFTAVIPT 171 + M+++ P Y+ +K + +Y+ Y + P Sbjct: 116 KMVFMSTCMVYDKATNIQGISELDPIKPASPYAGSKIAAENMVLSYYYAYKLPVVVIRPF 175 Query: 172 NVFGPHDNFNIEDGHVLPGLIHKVHLAKSSGSALTVWGTGNPRRQFIYSLDLAQLFIWVL 231 N +GP E G V + +K L ++G G R +Y D A F+ Sbjct: 176 NTYGPFQKTGGEGGVVAIFINNK-----LDNVPLNIYGDGKQTRDLLYVEDCAD-FVVAA 229 Query: 232 REYNEVEPIILSVGEEDEVSIKEAAEAVVEAMDFHGEVTFDTTKSDGQFKKTASNSKLRT 291 + I++ G ++SI + AE + VT +S+ Q K + K +T Sbjct: 230 GYSAKANGHIINAGTGQDISINKLAELISGNKVSIQHVTHIHPQSEIQ-KLLCNYEKAKT 288 Query: 292 YLPDFRFTPFKQAVKETCAW 311 L + V +T W Sbjct: 289 ILNWEPKVSLEDGVIKTEEW 308 >1OC2-A nrPDB Length = 348 Score = 223 bits (567), Expect = 1e-58, Method: Composition-based stats. Identities = 68/343 (19%), Positives = 121/343 (35%), Gaps = 53/343 (15%) Query: 8 MRILVTGGSGLVGKAIQK-----------VVADGAGLPG-------EDWVFVSSKDADLT 49 I+VTGG+G +G V D G V D+ Sbjct: 5 KNIIVTGGAGFIGSNFVHYVYNNHPDVHVTVLDKLTYAGNKANLEAILGDRVELVVGDIA 64 Query: 50 DTAQTRALFEKVQPTHVIHLAAMVGGLFRNIKYNLDFWRKNVHMNDNVLHSAFEVGARKV 109 D L K ++H AA ++ F N +L +A + + Sbjct: 65 DAELVDKLAAK--ADAIVHYAAE-SHNDNSLNDPSPFIHTNFIGTYTLLEAARKYDI-RF 120 Query: 110 VSCLSTCIFPDKTTYPIDE----------TMIHNGPPHNSNFGYSYAKRMIDVQNRAYFQ 159 + ++ D P+ E +N + YS K D+ +A+ + Sbjct: 121 HHVSTDEVYGD---LPLREDLPGHGEGPGEKFTAETNYNPSSPYSSTKAASDLIVKAWVR 177 Query: 160 QYGCTFTAVIPTNVFGPHDNFNIEDGHVLPGLIHKVHLAKSSGSALTVWGTGNPRRQFIY 219 +G T +N +GP+ + + I + +G ++G G R +I+ Sbjct: 178 SFGVKATISNCSNNYGPYQH--------IEKFIPRQITNILAGIKPKLYGEGKNVRDWIH 229 Query: 220 SLDLAQLFIWVLREYNEVEPIILSVGEEDEVSIKEAAEAVVEAM----DFHGEVTFDTTK 275 + D + +W + + +G + E + KE E ++E M D + VT + Sbjct: 230 TNDHSTG-VWAILTKGRM-GETYLIGADGEKNNKEVLELILEKMGQPKDAYDHVT---DR 284 Query: 276 SDGQFKKTASNSKLRTYLPDFR-FTPFKQAVKETCAWFTDNYE 317 + + SKLR L FT F + ++ET W+TDN + Sbjct: 285 AGHDLRYAIDASKLRDELGWTPQFTDFSEGLEETIQWYTDNQD 327 >6BI4-A nrPDB Length = 346 Score = 222 bits (566), Expect = 1e-58, Method: Composition-based stats. Identities = 55/331 (16%), Positives = 118/331 (35%), Gaps = 35/331 (10%) Query: 7 SMRILVTGGSGLVGKAIQK-VVADGAGLPGEDWVFVS------------------SKDAD 47 +M ILVTGG+G +G ++ ++ ++ + Sbjct: 24 AMNILVTGGAGFIGSNFVHYMLQSYETYKIINFDALTYSGNLNNVKSIQDHPNYYFVKGE 83 Query: 48 LTDTAQTRALFEKVQPTHVIHLAAMVGGLFRNIKYNLDFWRKNVHMNDNVLHSAFEVGAR 107 + + + ++ +++ AA + R+I+ + F+ NV +L + Sbjct: 84 IQNGELLEHVIKERDVQVIVNFAAE-SHVDRSIENPIPFYDTNVIGTVTLLELVKKYPHI 142 Query: 108 KVVSCLSTCIFPDKTTYPIDETMIHNGPPHNSNFGYSYAKRMIDVQNRAYFQQYGCTFTA 167 K+V + ++ P N YS +K D+ AY++ Y Sbjct: 143 KLVQVSTDEVYGSLGK----TGRFTEETPLAPNSPYSSSKASADMIALAYYKTYQLPVIV 198 Query: 168 VIPTNVFGPHDNFNIEDGHVLPGLIHKVHLAKSSGSALTVWGTGNPRRQFIYSLDLAQLF 227 +N +GP+ LI + G L ++G G R +++ D Sbjct: 199 TRCSNNYGPYQYPE--------KLIPLMVTNALEGKKLPLYGDGLNVRDWLHVTDHCSAI 250 Query: 228 IWVLREYNEVEPIILSVGEEDEVSIKEAAEAVVEAMDF-HGEVTFDTTKSDGQFKKTASN 286 VL + E + ++G +E + E E ++ + ++ + T + + + Sbjct: 251 DVVLHKGRVGE--VYNIGGNNEKTNVEVVEQIITLLGKTKKDIEYVTDRLGHDRRYAINA 308 Query: 287 SKLRTYLPDFRFTPFKQAVKETCAWFTDNYE 317 K++ F+Q ++ET W+ N E Sbjct: 309 EKMKNEFDWEPKYTFEQGLQETVQWYEKNEE 339 >3M2P-A nrPDB Length = 311 Score = 217 bits (553), Expect = 4e-57, Method: Composition-based stats. Identities = 57/307 (18%), Positives = 123/307 (40%), Gaps = 26/307 (8%) Query: 7 SMRILVTGGSGLVGKAIQKVVADGAGLPGEDWVFVSSKDAD-----LTDTAQTRALFEKV 61 S++I VTGG+G +G+ + + + + P + +K + ++D + + Sbjct: 2 SLKIAVTGGTGFLGQYVVESIKNDGNTPIILTRSIGNKAINDYEYRVSDYTLEDLINQLN 61 Query: 62 QPTHVIHLAAMVGGLFRNIKYNLDFWRKNVHMNDNVLHSAFEVGARKVVSCLSTCIFPDK 121 V+HLAA G + + + N + N+ + +E +V + + D+ Sbjct: 62 DVDAVVHLAATRGS-----QGKISEFHDNEILTQNLYDACYENNISNIVYASTISAYSDE 116 Query: 122 TTYPIDETMIHNGPPHNSNFGYSYAKRMIDVQNRAYFQQYGCTFTAVIPTNVFGPHDNFN 181 T+ P +E + + Y +K + Y ++ G + +++G FN Sbjct: 117 TSLPWNEKEL-----PLPDLMYGVSKLACEHIGNIYSRKKGLCIKNLRFAHLYG----FN 167 Query: 182 IEDGHVLPGLIHKVHLAKSSGSALTVWGTGNPRRQFIYSLDLAQLFIWVLREYNEVEPII 241 ++ + +I++ G LT+ +R+F+Y+ D A+ I+ L++ E Sbjct: 168 EKNNY----MINRFFRQAFHGEQLTLHANSVAKREFLYAKDAAKSVIYALKQ--EKVSGT 221 Query: 242 LSVGEEDEVSIKEAAEAVVEAMDFHGEVTFDTTKS-DGQFKKTASNSKLRTYLPDFRFTP 300 ++G D ++ E A + A + + +G +SK + L Sbjct: 222 FNIGSGDALTNYEVANTINNAFGNKDNLLVKNPNANEGIHSSYMDSSKAKELLDFSTDYN 281 Query: 301 FKQAVKE 307 F AV+E Sbjct: 282 FATAVEE 288 >1I3M-A nrPDB Length = 348 Score = 213 bits (541), Expect = 9e-56, Method: Composition-based stats. Identities = 68/342 (19%), Positives = 121/342 (35%), Gaps = 40/342 (11%) Query: 9 RILVTGGSGLVGKAIQKVVADGAGLP------------------------GEDWVFVSSK 44 ++LVTGG+G +G + + LP V + Sbjct: 4 KVLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRSVEFE 63 Query: 45 DADLTDTAQTRALFEKVQPTHVIHLAAMVGGLFRNIKYNLDFWRKNVHMNDNVLHSAFEV 104 + D+ D + LF+K VIH A + + +++ LD++R N+ +L Sbjct: 64 EMDILDQGALQRLFKKYSFMAVIHFAGL-KAMGESVQKPLDYYRVNLTGTIQLLEIMKAH 122 Query: 105 GARKVVSCLSTCIFPDKTTYPIDETMIHNGPPHNSNFGYSYAKRMIDVQNRAYFQQ-YGC 163 G + +V S ++ + P+DE P Y +K I+ R Q Sbjct: 123 GVKNLVFSSSATVYGNPQYLPLDEAH----PTGGCTNPYGKSKFFIEEMIRDLCQADKTW 178 Query: 164 TFTAVIPTNVFGPHDNFNI-EDGHVLPG--LIHKVHLAKSSGSALTVWG------TGNPR 214 + N G H + I ED +P + + +A AL V+G G Sbjct: 179 NVVLLRYFNPTGAHASGCIGEDPQGIPNNLMPYVSQVAIGRREALNVFGNDYDTEDGTGV 238 Query: 215 RQFIYSLDLAQLFIWVLREYNE-VEPIILSVGEEDEVSIKEAAEAVVEAMDFHGEVTFDT 273 R +I+ +DLA+ I LR+ E I ++G S+ + +A+ +A Sbjct: 239 RDYIHVVDLAKGHIAALRKLKEQCGCRIYNLGTGTGYSVLQMVQAMEKASGKKIPYKVVA 298 Query: 274 TKSDGQFKKTASNSKLRTYLPDFRFTPFKQAVKETCAWFTDN 315 + A+ S + L + ++ W N Sbjct: 299 RREGDVAACYANPSLAQEELGWTAALGLDRMCEDLWRWQKQN 340 >1UDA-A nrPDB Length = 338 Score = 187 bits (474), Expect = 7e-48, Method: Composition-based stats. Identities = 58/333 (17%), Positives = 119/333 (35%), Gaps = 34/333 (10%) Query: 8 MRILVTGGSGLVGKAI-QKVVADGAGLPGEDWVFVSSK-----------------DADLT 49 MR+LVTGGSG +G +++ +G + D + S + + D+ Sbjct: 1 MRVLVTGGSGYIGSHTCVQLLQNGHDVIILDNLCNSKRSVLPVIERLGGKHPTFVEGDIR 60 Query: 50 DTAQTRALFEKVQPTHVIHLAAMVGGLFRNIKYNLDFWRKNVHMNDNVLHSAFEVGARKV 109 + A + VIH A + + +++ L+++ NV+ ++ + + Sbjct: 61 NEALMTEILHDHAIDTVIHFAGL-KAVGESVQKPLEYYDNNVNGTLRLISAMRAANVKNF 119 Query: 110 VSCLSTCIFPDKTTYPIDETMIHNGPPHNSNFGYSYAKRMIDVQNRAYFQQY-GCTFTAV 168 + S ++ D P E+ P Y +K M++ + + + Sbjct: 120 IFSSSATVYGDNPKIPYVESF----PTGTPQSPYGKSKLMVEQILTDLQKAQPDWSIALL 175 Query: 169 IPTNVFGPHDNFN-IEDGHVLPG--LIHKVHLAKSSGSALTVWG------TGNPRRQFIY 219 N G H + + ED +P + + +A +L ++G G R +I+ Sbjct: 176 RYFNPVGAHPSGDMGEDPQGIPNNLMPYIAQVAVGRRDSLAIFGNDYPTEDGTGVRDYIH 235 Query: 220 SLDLAQLFIWVLREY-NEVEPIILSVGEEDEVSIKEAAEAVVEAMDFHGEVTFDTTKSDG 278 +DLA + + + N+ I ++G S+ + A +A F + Sbjct: 236 VMDLADGHVVAMEKLANKPGVHIYNLGAGVGNSVLDVVNAFSKACGKPVNYHFAPRREGD 295 Query: 279 QFKKTASNSKLRTYLPDFRFTPFKQAVKETCAW 311 A SK L + ++T W Sbjct: 296 LPAYWADASKADRELNWRVTRTLDEMAQDTWHW 328 >1Z45-A nrPDB Length = 699 Score = 183 bits (464), Expect = 1e-46, Method: Composition-based stats. Identities = 68/343 (19%), Positives = 124/343 (36%), Gaps = 36/343 (10%) Query: 7 SMRILVTGGSGLVGKA-IQKVVADGAGLPGEDWVF-----------------VSSKDADL 48 S +LVTGG+G +G + +++ +G D + + + DL Sbjct: 11 SKIVLVTGGAGYIGSHTVVELIENGYDCVVADNLSNSTYDSVARLEVLTKHHIPFYEVDL 70 Query: 49 TDTAQTRALFEKVQPTHVIHLAAMVGGLFRNIKYNLDFWRKNVHMNDNVLHSAFEVGARK 108 D +F++ + VIH A + + + + L ++ N+ +L + K Sbjct: 71 CDRKGLEKVFKEYKIDSVIHFAGL-KAVGESTQIPLRYYHNNILGTVVLLELMQQYNVSK 129 Query: 109 VVSCLSTCIFPDKTTYPIDETMIHNGPPHNSNFGYSYAKRMIDVQNRAYF--QQYGCTFT 166 V S ++ D T +P I P Y + K I+ + + F Sbjct: 130 FVFSSSATVYGDATRFPNMIP-IPEECPLGPTNPYGHTKYAIENILNDLYNSDKKSWKFA 188 Query: 167 AVIPTNVFGPHDNFNI-EDGHVLPG--LIHKVHLAKSSGSALTVWG------TGNPRRQF 217 + N G H + I ED +P L + +A L ++G G P R + Sbjct: 189 ILRYFNPIGAHPSGLIGEDPLGIPNNLLPYMAQVAVGRREKLYIFGDDYDSRDGTPIRDY 248 Query: 218 IYSLDLAQLFIWV---LREYNEVEPII--LSVGEEDEVSIKEAAEAVVEAMDFHGEVTFD 272 I+ +DLA+ I L YNE E + ++G ++ E A +A Sbjct: 249 IHVVDLAKGHIAALQYLEAYNENEGLCREWNLGSGKGSTVFEVYHAFCKASGIDLPYKVT 308 Query: 273 TTKSDGQFKKTASNSKLRTYLPDFRFTPFKQAVKETCAWFTDN 315 ++ TA + + L + + K+ W T+N Sbjct: 309 GRRAGDVLNLTAKPDRAKRELKWQTELQVEDSCKDLWKWTTEN 351 >2C20-A nrPDB Length = 330 Score = 169 bits (428), Expect = 1e-42, Method: Composition-based stats. Identities = 69/334 (20%), Positives = 120/334 (35%), Gaps = 29/334 (8%) Query: 10 ILVTGGSGLVGKA-IQKVVADGAGLPGEDWVFVSSKD----------ADLTDTAQTRALF 58 IL+ GG+G +G ++K+V +G + D + +D DL D A R +F Sbjct: 4 ILICGGAGYIGSHAVKKLVDEGLSVVVVDNLQTGHEDAITEGAKFYNGDLRDKAFLRDVF 63 Query: 59 EKVQPTHVIHLAAMVGGLFRNIKYNLDFWRKNVHMNDNVLHSAFEVGARKVVSCLSTCIF 118 + V+H AA + +++ L ++ NV+ +L E K + + + Sbjct: 64 TQENIEAVMHFAA-DSLVGVSMEKPLQYYNNNVYGALCLLEVMDEFKVDKFIFSSTAATY 122 Query: 119 PDKTTYPIDETMIHNGPPHNSNFGYSYAKRMIDVQNRAYFQQYGCTFTAVIPTNVFGPHD 178 +D +I N Y K I+ Y Q + NV G Sbjct: 123 G-----EVDVDLITEETMTNPTNTYGETKLAIEKMLHWYSQASNLRYKIFRYFNVAGATP 177 Query: 179 NFNIEDGH-VLPGLIH-KVHLAKSSGSALTVWG------TGNPRRQFIYSLDLAQLFIWV 230 N I + H LI + +A + ++G G R +I+ DL Sbjct: 178 NGIIGEDHRPETHLIPLVLQVALGQREKIMMFGDDYNTPDGTCIRDYIHVEDLVAAHFLG 237 Query: 231 LREY-NEVEPIILSVGEEDEVSIKEAAEAVVEAMDFHGEVTFDTTKSDGQF-KKTASNSK 288 L++ N E ++G + S+KE +AV E + H + G + AS+ K Sbjct: 238 LKDLQNGGESDFYNLGNGNGFSVKEIVDAVREVTN-HEIPAEVAPRRAGDPARLVASSQK 296 Query: 289 LRTYLPDFR-FTPFKQAVKETCAWFTDNYEQARK 321 + L + K ++ W K Sbjct: 297 AKEKLGWDPRYVNVKTIIEHAWNWHQKQPNGYEK 330 >4LIS-A nrPDB Length = 371 Score = 167 bits (422), Expect = 6e-42, Method: Composition-based stats. Identities = 76/362 (20%), Positives = 130/362 (35%), Gaps = 48/362 (13%) Query: 4 PQGSMRILVTGGSGLVGK-AIQKVVADGAGLPGEDWVFVSSKDA---------------- 46 P GS +LVTGG+G +G ++ G + D ++ SS +A Sbjct: 2 PSGS--VLVTGGTGYIGSFTTLALLEAGYKVVVADNLYNSSAEALNRIELISGKKAEFAQ 59 Query: 47 -DLTDTAQTRALFEKV-QPTHVIHLAAMVGGLFRNIKYNLDFWRKNVHMNDNVLHSAFEV 104 D+TD A +FE VIH AA+ + + + LD++ NV+ +L S Sbjct: 60 LDVTDEAAFDKVFEAHPDIDSVIHFAAL-KAVGESGEKPLDYYHVNVYGTICLLRSMVRH 118 Query: 105 GARKVVSCLSTCIFPDKTTYPIDETMIHNGPPHNSNFGYSYAKRMIDVQN---------- 154 +V S ++ D T +P D I P Y K I++ Sbjct: 119 NVTNIVFSSSATVYGDATRFP-DMIPIPEHCPLGPTNPYGNTKFAIELAITDVINAQRNN 177 Query: 155 --RAYFQQYGCTFT--AVIPTNVFGPHDNF-NIEDGHVLPG--LIHKVHLAKSSGSALTV 207 +A + + + N G H + ED +P L +A L V Sbjct: 178 AKKAGNETEAAKWNGALLRYFNPAGAHPSGIMGEDPQGVPYNLLPLLAQVATGKREKLLV 237 Query: 208 WG------TGNPRRQFIYSLDLAQLFIWVLREYNEVEPI--ILSVGEEDEVSIKEAAEAV 259 +G G R +I+ LDLA + L P ++G ++ E A Sbjct: 238 FGDDYASHDGTAIRDYIHILDLADGHLKALNYLRANNPGVRAWNLGTGRGSTVYEMIRAF 297 Query: 260 VEAMDFHGEVTFDTTKSDGQFKKTASNSKLRTYLPDFRFTPFKQAVKETCAWFTDNYEQA 319 +A+ ++ T++ ++ T L +QA ++ W +N + Sbjct: 298 SKAVGRDLPYEVAPRRAGDVLNLTSNPTRANTELGWKAQRTLEQACEDLWLWTKNNPQGY 357 Query: 320 RK 321 R+ Sbjct: 358 RQ 359 >1GY8-A nrPDB Length = 397 Score = 161 bits (406), Expect = 4e-40, Method: Composition-based stats. Identities = 59/370 (15%), Positives = 124/370 (33%), Gaps = 71/370 (19%) Query: 8 MRILVTGGSGLVGKAIQKVVADGAGLPGEDWVFV----------SSKD------------ 45 MR+LV GG+G +G + + + +++ Sbjct: 3 MRVLVCGGAGYIGSHFVRALLRDTNHSVVIVDSLVGTHGKSDHVETRENVARKLQQSDGP 62 Query: 46 -------------ADLTDTAQTRALFEKVQP-THVIHLAAMVGGLFRNIKYNLDFWRKNV 91 D+ + +F + P V+H+ A + + +++ L ++ NV Sbjct: 63 KPPWADRYAALEVGDVRNEDFLNGVFTRHGPIDAVVHMCAFLA-VGESVRDPLKYYDNNV 121 Query: 92 HMNDNVLHSAFEVGARKVVSCLSTCIFPDKTTYPIDE--TMIHNGPPHNSNFGYSYAKRM 149 +L + K++ S IF + T + I + Y +K + Sbjct: 122 VGILRLLQAMLLHKCDKIIFSSSAAIFGNPTMGSVSTNAEPIDINAKKSPESPYGESKLI 181 Query: 150 IDVQNRAYFQQYGCTFTAVIPTNVFGPHDNFNIED-----GHVLPGLIHK---------- 194 + R + YG + N G H++ +I + H++P ++ + Sbjct: 182 AERMIRDCAEAYGIKGICLRYFNACGAHEDGDIGEHYQGSTHLIPIILGRVMSDIAPDQR 241 Query: 195 --VHLAKSSGSALTVWG------TGNPRRQFIYSLDLAQLFIWVLREYNEVEPI------ 240 +H S+ + ++G G R +++ DLA I L ++ P Sbjct: 242 LTIHEDASTDKRMPIFGTDYPTPDGTCVRDYVHVCDLASAHILALDYVEKLGPNDKSKYF 301 Query: 241 -ILSVGEEDEVSIKEAAEAVVEAMDFHGEVTFDTTKSDGQFKKTASNS-KLRTYLPDFRF 298 + ++G S++E E + H + + +G + S K R L Sbjct: 302 SVFNLGTSRGYSVREVIEVARKTTG-HPIPVRECGRREGDPAYLVAASDKAREVLGWKPK 360 Query: 299 TPFKQAVKET 308 +A+ ET Sbjct: 361 YDTLEAIMET 370 >3ENK-A nrPDB Length = 341 Score = 158 bits (400), Expect = 3e-39, Method: Composition-based stats. Identities = 64/336 (19%), Positives = 127/336 (37%), Gaps = 37/336 (11%) Query: 10 ILVTGGSGLVGKAI-QKVVADGAGLPGEDWVFVSSKDA-----------------DLTDT 51 ILVTGG+G +G +++A G + D + S ++A D++D Sbjct: 8 ILVTGGAGYIGSHTAVELLAHGYDVVIADNLVNSKREAIARIEKITGKTPAFHETDVSDE 67 Query: 52 AQTRALFEKVQPTHVIHLAAMVGGLFRNIKYNLDFWRKNVHMNDNVLHSAFEVGARKVVS 111 +F+ T IH AA+ + ++ ++++R N+ ++L E +++V Sbjct: 68 RALARIFDAHPITAAIHFAAL-KAVGESVAKPIEYYRNNLDSLLSLLRVMRERAVKRIVF 126 Query: 112 CLSTCIFPDKTTYPIDETMIHNGPPHNSNFGYSYAKRMIDVQNRAYFQQYGCTFTA--VI 169 S ++ PIDET P ++ Y K M + R + ++ + Sbjct: 127 SSSATVYGVPERSPIDETF-----PLSATNPYGQTKLMAEQILRD-VEAADPSWRVATLR 180 Query: 170 PTNVFGPHDNFNI-EDGHVLPG--LIHKVHLAKSSGSALTVWG------TGNPRRQFIYS 220 N G H++ I ED +P + + +A L V+G G R +I+ Sbjct: 181 YFNPVGAHESGLIGEDPAGIPNNLMPYVAQVAVGKLEKLRVFGSDYPTPDGTGVRDYIHV 240 Query: 221 LDLAQLFIWVLREYNEVE-PIILSVGEEDEVSIKEAAEAVVEAMDFHGEVTFDTTKSDGQ 279 +DLA+ I L + + +++G S+ E A +A + Sbjct: 241 VDLARGHIAALDALERRDASLTVNLGTGRGYSVLEVVRAFEKASGRAVPYELVARRPGDV 300 Query: 280 FKKTASNSKLRTYLPDFRFTPFKQAVKETCAWFTDN 315 + A+ + + ++ + W +N Sbjct: 301 AECYANPAAAAETIGWKAERDLERMCADHWRWQENN 336 >2PZM-A nrPDB Length = 330 Score = 154 bits (390), Expect = 3e-38, Method: Composition-based stats. Identities = 64/326 (19%), Positives = 109/326 (33%), Gaps = 45/326 (13%) Query: 4 PQGS-MRILVTGGSGLVGKA-IQKVVADGAGLPGEDWVFVSSKD------------ADLT 49 P+GS MRIL+TGG+G +G I+ + G + D ++ +T Sbjct: 16 PRGSHMRILITGGAGCLGSNLIEHWLPQGHEILVIDNFATGKREVLPPVAGLSVIEGSVT 75 Query: 50 DTAQTRALFEKVQPTHVIHLAAMVGGLFRNIKYNLDFWRKNVHMNDNVLHSAFEVGARKV 109 D F+ +PTHV+H AA + NV + NV +A + G +++ Sbjct: 76 DAGLLERAFDSFKPTHVVHSAAAYKDPDDWAEDAA----TNVQGSINVAKAASKAGVKRL 131 Query: 110 VSCLSTCIFPDKTTYPIDETMIHNGPPHNSNFGYSYAKRMIDVQNRAYFQQYGCTFTAVI 169 ++ + + T PI P Y +K + A+ ++ Sbjct: 132 LNFQTALCYGRPATVPI-----PIDSPTAPFTSYGISKTAGE----AFLMMSDVPVVSLR 182 Query: 170 PTNVFGPHDNFNIEDGHVLPGLIHKVHLAKSSGSALTVWGTGNPRRQFIYSLDLAQLFIW 229 NV GP I + +G + R F+ D++ Sbjct: 183 LANVTGPRLAIGP---------IPTFYKRLKAGQKCFC---SDTVRDFL---DMSDFLAI 227 Query: 230 VLREYNEVEP-IILSVGEEDEVSIKEAAEAVVEAMDFH--GEVTFDTTKSDGQFKKTASN 286 E P + +V + SIKE + V++ + V +D Sbjct: 228 ADLSLQEGRPTGVFNVSTGEGHSIKEVFDVVLDYVGATLAEPVPVVAPGADDVPSVVLDP 287 Query: 287 SKLRTYLPDFRFTPFKQAVKETCAWF 312 SK T FK + AW+ Sbjct: 288 SKTETEFGWKAKVDFKDTITGQLAWY 313 >2C54-A nrPDB Length = 379 Score = 151 bits (380), Expect = 5e-37, Method: Composition-based stats. Identities = 57/328 (17%), Positives = 116/328 (35%), Gaps = 18/328 (5%) Query: 4 PQGSMRILVTGGSGLVGKAIQKVVADGAGLP-GEDWVFVSSKDADL-TDTAQTRALF--- 58 P +++I +TG G + I + + DW D+ D L Sbjct: 26 PSENLKISITGAGGFIASHIARRLKHEGHYVIASDWKKNEHMTEDMFCDEFHLVDLRVME 85 Query: 59 EKVQP----THVIHLAAMVGGLFRNIKYNLDFWRKNVHMNDNVLHSAFEVGARKVVSCLS 114 ++ HV +LAA +GG+ + N ++ N++ +A G ++ S Sbjct: 86 NCLKVTEGVDHVFNLAADMGGMGFIQSNHSVIMYNNTMISFNMIEAARINGIKRFFYASS 145 Query: 115 TCIFPDKTTYPIDETMIHNGP--PHNSNFGYSYAKRMIDVQNRAYFQQYGCTFTAVIPTN 172 CI+P+ + P Y + + + Y + +G N Sbjct: 146 ACIYPEFKQLETTNVSLKESDAWPAEPQDAYGLERLATEELCKHYNKDFGIECRIGRFHN 205 Query: 173 VFGPHDNFNIEDGHVLPGLIHKVHLAKSSGSALTVWGTGNPRRQFIYSLDLAQLFIWVLR 232 ++GP + A++S +WG G R F + + + VLR Sbjct: 206 IYGPFGTWKGGREKAPAAF---CRKAQTSTDRFEMWGDGLQTRSFTFIDECVEG---VLR 259 Query: 233 EYNEVEPIILSVGEEDEVSIKEAAEAVVEAMDFHGEVTFDTTKSDGQFKKTASNSKLRTY 292 +++G ++ VS+ E AE V+ + + +G + + N+ ++ Sbjct: 260 LTKSDFREPVNIGSDEMVSMNEMAEMVL-SFEEKKLPIHHIPGPEGVRGRNSDNNLIKEK 318 Query: 293 LPDFRFTPFKQAVKETCAWFTDNYEQAR 320 L K+ ++ T W + E+ + Sbjct: 319 LGWAPNMRLKEGLRITYFWIKEQIEKEK 346 >4WKG-A nrPDB Length = 660 Score = 148 bits (372), Expect = 4e-36, Method: Composition-based stats. Identities = 54/347 (15%), Positives = 121/347 (34%), Gaps = 39/347 (11%) Query: 9 RILVTGGSGLVGKAIQKVVADGAGLPGEDWVFVSSKDADLTDTAQTRALFEKVQPTHVIH 68 R+L+ G +G +G + + + S + + F V+ IH Sbjct: 317 RVLILGVNGFIGNHLTERLLREDHYEVYGLDIGSDAISRFLNHPH----FHFVEGDISIH 372 Query: 69 LAAMVGGLFR--------NIKYNLDFWRKNVHM-------NDNVLHSAFEVGARKVVSCL 113 + + + I +++ R + + N ++ + ++++ Sbjct: 373 SEWIEYHVKKCDVVLPLVAIATPIEYTRNPLRVFELDFEENLRIIRYCVKYR-KRIIFPS 431 Query: 114 STCIFP--DKTTYPIDETMIHNGPPHNSNFGYSYAKRMIDVQNRAYFQQYGCTFTAVIPT 171 ++ ++ + D + + GP + + YS +K+++D AY ++ G FT P Sbjct: 432 TSEVYGMCSDKYFDEDHSNLIVGPVNKPRWIYSVSKQLLDRVIWAYGEKEGLQFTLFRPF 491 Query: 172 NVFGPHDNFNIEDGHVLPGLIHKVHLAKSSGSALTVWGTGNPRRQFIYSLD-LAQLFIWV 230 N GP + I ++ L GS + + G +R F D + L+ + Sbjct: 492 NWMGPRLDNLNAARIGSSRAITQLILNLVEGSPIKLIDGGKQKRCFTDIRDGIEALYRII 551 Query: 231 LREYNEVEPIILSVGE-EDEVSIKEAAEAVVEAMDFHG---------------EVTFDTT 274 N + I+++G E+E SI+E E ++ + + H ++ Sbjct: 552 ENAGNRCDGEIINIGNPENEASIEELGEMLLASFEKHPLRHHFPPFAGFRVVESSSYYGK 611 Query: 275 KSDGQFKKTASNSKLRTYLPDFRFTPFKQAVKETCAWFTDNYEQARK 321 + S L ++ + ET +F + K Sbjct: 612 GYQDVEHRKPSIRNAHRCLDWEPKIDMQETIDETLDFFLRTVDLTDK 658 >2Q1T-A nrPDB Length = 377 Score = 145 bits (366), Expect = 2e-35, Method: Composition-based stats. Identities = 62/328 (18%), Positives = 110/328 (33%), Gaps = 27/328 (8%) Query: 10 ILVTGGSGLVGKA-IQKVVADGAGLPGEDWVFVSSKDAD-------------LTDTAQTR 55 ++V GG+G VG +++++ G +S++ + +TD A Sbjct: 35 VMVVGGAGFVGSNLVKRLLELGVNQVHVVDNLLSAEKINVPDHPAVRFSETSITDDALLA 94 Query: 56 ALFEKVQPTHVIHLAAMVGGLFRNIKYNLDFWRKNVHMNDNVLHSAFEV-GARKVVSCLS 114 +L ++ +V HLA G +I L N + +KVV + Sbjct: 95 SLQDEY--DYVFHLATYHGNQ-SSIHDPLADHENNTLTTLKLYERLKHFKRLKKVVYSAA 151 Query: 115 TCIFPDKTTY-PIDETMIHNGPPHNSNFGYSYAKRMIDVQNRAYFQQYGCTFTAVIPTNV 173 C +KT HN++ YS +K + + Y +Q+ NV Sbjct: 152 GCSIAEKTFDDAKATEETDIVSLHNNDSPYSMSKIFGEFYSVYYHKQHQLPTVRARFQNV 211 Query: 174 FGPHDNFNIEDGHVLP-----GLIHKVHLAKSSGSALTVWGTGNPRRQFIYSLDLAQLFI 228 +GP + P + G L + G R FI+ D+A I Sbjct: 212 YGPGEILGAGRWRGTPATVWRNVTPTFIYKALKGMPLPLENGGVATRDFIFVEDVANGLI 271 Query: 229 WVLREYNEVEPIILSVGEEDEVSIKEAAEAVVEAMDFHGEVTFDTTKS-DGQFKKTASNS 287 + + ++ E SI + A + E + E+ + D K+ S Sbjct: 272 AC--AADGTPGGVYNIASGKETSIADLATKINEITGNNTELDRLPKRPWDNSGKRFGSPE 329 Query: 288 KLRTYLPDFRFTPFKQAVKETCAWFTDN 315 K R L +++T W N Sbjct: 330 KARRELGFSADVSIDDGLRKTIEWTKAN 357 >1ORR-A nrPDB Length = 347 Score = 142 bits (358), Expect = 2e-34, Method: Composition-based stats. Identities = 53/334 (15%), Positives = 106/334 (31%), Gaps = 32/334 (9%) Query: 9 RILVTGGSGLVGKAIQK---------VVADGAGLPG--------EDWVFVSSKDADLTDT 51 ++L+TGG G +G + +V D G D+ + Sbjct: 3 KLLITGGCGFLGSNLASFALSQGIDLIVFDNLSRKGATDNLHWLSSLGNFEFVHGDIRNK 62 Query: 52 AQTRALFEKVQPTHVIHLAAMVGGLFRNIKYNLDFWRKNVHMNDNVLHSAFEVGAR-KVV 110 L K P HLA V + +I + NV N+L + + + ++ Sbjct: 63 NDVTRLITKYMPDSCFHLAGQVA-MTTSIDNPCMDFEINVGGTLNLLEAVRQYNSNCNII 121 Query: 111 SCLSTCIFPDKTTYPIDETMIHNGPPHNSN-----------FGYSYAKRMIDVQNRAYFQ 159 + ++ D Y +ET N Y +K D Y + Sbjct: 122 YSSTNKVYGDLEQYKYNETETRYTCVDKPNGYDESTQLDFHSPYGCSKGAADQYMLDYAR 181 Query: 160 QYGCTFTAVIPTNVFGPHDNFNIEDGHVLPGLIHKVHLAKSSGSALTVWGTGNPRRQFIY 219 +G ++++G + G V V + T+ G G R ++ Sbjct: 182 IFGLNTVVFRHSSMYGGRQFATYDQGWVGWFCQKAVEIKNGINKPFTISGNGKQVRDVLH 241 Query: 220 SLDLAQLFIWVLREYNEVEPIILSVGEE--DEVSIKEAAEAVVEAMDFHGEVTFDTTKSD 277 + D+ L+ L +++ ++G + +S+ E + + + + T + Sbjct: 242 AEDMISLYFTALANVSKIRGNAFNIGGTIVNSLSLLELFKLLEDYCNIDMRFTNLPVRES 301 Query: 278 GQFKKTASNSKLRTYLPDFRFTPFKQAVKETCAW 311 Q A K+ + K V++ W Sbjct: 302 DQRVFVADIKKITNAIDWSPKVSAKDGVQKMYDW 335 >2PK3-A nrPDB Length = 321 Score = 140 bits (352), Expect = 8e-34, Method: Composition-based stats. Identities = 48/321 (14%), Positives = 109/321 (33%), Gaps = 23/321 (7%) Query: 6 GSMRILVTGGSGLVGK----AIQKVVADGAGLPGEDWVFVSSKDA---DLTDTAQTRALF 58 GSMR L+TG +G VGK + + + G + + + + D+ D+ + + + Sbjct: 11 GSMRALITGVAGFVGKYLANHLTEQNVEVFGTSRNNEAKLPNVEMISLDIMDSQRVKKVI 70 Query: 59 EKVQPTHVIHLAAMVGGLFRNIKYNLDFWRKNVHMNDNVLHSAFEVGAR-KVVSCLSTCI 117 ++P ++ HLAA + F NV +VL + + ++++ S+ Sbjct: 71 SDIKPDYIFHLAAKSSVKDSWLNKKGTF-STNVFGTLHVLDAVRDSNLDCRILTIGSSEE 129 Query: 118 FPD--KTTYPIDETMIHNGPPHNSNFGYSYAKRMIDVQNRAYFQQYGCTFTAVIPTNVFG 175 + P+ E Y +K + + R Y + YG N G Sbjct: 130 YGMILPEESPVSEENQLR-----PMSPYGVSKASVGMLARQYVKAYGMDIIHTRTFNHIG 184 Query: 176 PHDNFNIEDGHVLPGLIHKVHLAKSSGSALTVWGTGNPRRQFIYSLDLAQLFIWVLREYN 235 P + ++ + + G R F D+ Q + + + Sbjct: 185 PGQSLGFVTQDFAKQIVD---IEMEKQEPIIKVGNLEAVRDFTDVRDIVQAYWLLSQYGK 241 Query: 236 EVEPIILSVGEEDEVSIKEAAEAVVEAMDFHGEVTFD--TTKSDGQFKKTASNSKLRTYL 293 + + +V I++ + ++ + + + + SN +L+ Sbjct: 242 TGD--VYNVCSGIGTRIQDVLDLLLAMANVKIDTELNPLQLRPSEVPTLIGSNKRLKDST 299 Query: 294 PDFRFTPFKQAVKETCAWFTD 314 P ++++ E + Sbjct: 300 GWKPRIPLEKSLFEILQSYRQ 320 >1VL0-A nrPDB Length = 292 Score = 115 bits (287), Expect = 3e-26, Method: Composition-based stats. Identities = 58/282 (20%), Positives = 107/282 (37%), Gaps = 37/282 (13%) Query: 8 MRILVTGGSGLVGKAIQKVVADGAGLPGEDWVFVSSKDADLTDTAQTRALFEKVQPTHVI 67 M+IL+TG +G +G+ IQK + + + +D D+T+ F + +P VI Sbjct: 13 MKILITGANGQLGREIQKQLKG----KNVEVIPTDVQDLDITNVLAVNKFFNEKKPNVVI 68 Query: 68 HLAAMVGGLFRNIKYNLDFWRKNVHMNDNVLHSAFEVGARKVVSCLSTCIFPDKTTYPID 127 + AA +Y+L + + N N+ +A+ VGA ++V + +F + PI Sbjct: 69 NCAAHTAVDKCEEQYDLAY-KINAIGPKNLAAAAYSVGA-EIVQISTDYVFDGEAKEPIT 126 Query: 128 ETMIHNGPPHNSNFGYSYAKRMIDVQNRAYFQQYGCTFTAVIPTNVFGPHDNFNIEDGHV 187 E N Y K + +A +Y V ++G + + Sbjct: 127 EFDEV-----NPQSAYGKTKLEGENFVKALNPKY----YIVRTAWLYG-------DGNNF 170 Query: 188 LPGLIHKVHLAKSSGSALTVWGT-GNPRRQFIYSLDLAQLFIWVLREYNEVEPIILSVGE 246 + +I+ L K+ V G P ++DLA+ VL+ +E Sbjct: 171 VKTMIN---LGKTHDELKVVHDQVGTPTS----TVDLAR---VVLKVIDEKNYGTFHCTC 220 Query: 247 EDEVSIKEAAEAVVEAMDFHGEVTFDTT----KSDGQFKKTA 284 + S + A + +VT TT + + K + Sbjct: 221 KGICSWYDFAVEIFRLTGIDVKVTPCTTEEFPRPAKRPKYSV 262 >1EQ2-A nrPDB Length = 310 Score = 114 bits (286), Expect = 4e-26, Method: Composition-based stats. Identities = 64/321 (19%), Positives = 110/321 (34%), Gaps = 36/321 (11%) Query: 10 ILVTGGSGLVGKAIQKVVADGAGLPGEDWV-------FVSSKDADLTDTAQTRALFEKV- 61 I+VTGG+G +G I K + D FV+ D ++ D ++ Sbjct: 2 IIVTGGAGFIGSNIVKALNDKGITDILVVDNLKDGTKFVNLVDLNIADYMDKEDFLIQIM 61 Query: 62 ------QPTHVIHLAAMVGGLFRNIKYNLDFWRKNVHMNDNVLHSAFEVGARKVVSCLST 115 + H A + KY +D N + +LH E + S Sbjct: 62 AGEEFGDVEAIFHEGACSSTTEWDGKYMMD---NNYQYSKELLHYCLEREIP-FLYASSA 117 Query: 116 CIFPDKTTYPIDETMIHNGPPHNSNFGYSYAKRMIDVQNRAYFQQYGCTFTAVIPTNVFG 175 + +T+ I+ Y Y+K + D R + NV+G Sbjct: 118 ATYGGRTSDFIESREY-----EKPLNVYGYSKFLFDEYVRQILPEANSQIVGFRYFNVYG 172 Query: 176 PHDNFNIEDGHVLPGLIHKVHLAKSSGSALTVWGTGNP-RRQFIYSLDLAQLFIWVLREY 234 P + V L +++ +G + ++ +R F+Y D+A + +W L Sbjct: 173 PREGHKGSMASVAFHLNTQLN----NGESPKLFEGSENFKRDFVYVGDVADVNLWFLENG 228 Query: 235 NEVEPIILSVGEEDEVSIKEAAEAVVEAMDFHGEVTF----DTTKSDGQFKKTASNSKLR 290 I ++G S + A+A + A G++ + D K Q A + LR Sbjct: 229 ---VSGIFNLGTGRAESFQAVADATL-AYHKKGQIEYIPFPDKLKGRYQAFTQADLTNLR 284 Query: 291 TYLPDFRFTPFKQAVKETCAW 311 D F + V E AW Sbjct: 285 AAGYDKPFKTVAEGVTEYMAW 305 >2X86-A nrPDB Length = 357 Score = 113 bits (283), Expect = 1e-25, Method: Composition-based stats. Identities = 63/321 (19%), Positives = 110/321 (34%), Gaps = 36/321 (11%) Query: 10 ILVTGGSGLVGKAIQKVVADGAGLPGEDWV-------FVSSKDADLTDTAQTRALFEKV- 61 I+VTGG+G +G I K + D FV+ D ++ D ++ Sbjct: 49 IIVTGGAGFIGSNIVKALNDKGITDILVVDNLKDGTKFVNLVDLNIADYMDKEDFLIQIM 108 Query: 62 ------QPTHVIHLAAMVGGLFRNIKYNLDFWRKNVHMNDNVLHSAFEVGARKVVSCLST 115 + H A + KY +D N + +LH E + S Sbjct: 109 AGEEFGDVEAIFHEGACSSTTEWDGKYMMD---NNYQYSKELLHYCLEREIP-FLYASSA 164 Query: 116 CIFPDKTTYPIDETMIHNGPPHNSNFGYSYAKRMIDVQNRAYFQQYGCTFTAVIPTNVFG 175 + +T+ I+ + Y+K + D R + NV+G Sbjct: 165 ATYGGRTSDFIESREY-----EKPLNVFGYSKFLFDEYVRQILPEANSQIVGFRYFNVYG 219 Query: 176 PHDNFNIEDGHVLPGLIHKVHLAKSSGSALTVWGTGNP-RRQFIYSLDLAQLFIWVLREY 234 P + V L +++ +G + ++ +R F+Y D+A + +W L Sbjct: 220 PREGHKGSMASVAFHLNTQLN----NGESPKLFEGSENFKRDFVYVGDVADVNLWFLENG 275 Query: 235 NEVEPIILSVGEEDEVSIKEAAEAVVEAMDFHGEVTF----DTTKSDGQFKKTASNSKLR 290 I ++G S + A+A + A G++ + D K Q A + LR Sbjct: 276 ---VSGIFNLGTGRAESFQAVADATL-AYHKKGQIEYIPFPDKLKGRYQAFTQADLTNLR 331 Query: 291 TYLPDFRFTPFKQAVKETCAW 311 D F + V E AW Sbjct: 332 AAGYDKPFKTVAEGVTEYMAW 352 >4EJ0-A nrPDB Length = 342 Score = 106 bits (263), Expect = 2e-23, Method: Composition-based stats. Identities = 56/341 (16%), Positives = 108/341 (31%), Gaps = 53/341 (15%) Query: 8 MRILVTGGSGLVGKAIQKVVADGAGLPGEDWVFVSSK-------DADLTDTAQTRALFEK 60 M ++VTG +G +G + K + + ++ D ++ D E+ Sbjct: 13 MTLIVTGAAGFIGANLVKALNERGETRIIAVDNLTRADKFKNLVDCEIDDYLDKTEFVER 72 Query: 61 V------QPTHVIHLAAMVGGLFRNIKYNLDFWRKNVHMNDNVLHSAFEVGARKVVSCLS 114 + V H A + + +Y +D N + VL + GA+ + S Sbjct: 73 FARGDFGKVRAVFHEGACSDTMETDGRYMMD---NNFRYSRAVLDACLAQGAQ-FLYASS 128 Query: 115 TCIFPDKTTYPIDETMIHNGPPHNSNFGYSYAKRMIDVQNRAYFQQYGCTFTAVIPTNVF 174 I+ + + Y Y+K + D R NV+ Sbjct: 129 AAIYGGSSR------FVEEREVEAPLNVYGYSKFLFDQVIRRVMPGAKSQIAGFRYFNVY 182 Query: 175 GPHDNFNIEDGHVLPGLIHKVHLAKSSGSALTVWGT------GNPRRQFIYSLDLAQLFI 228 GP ++ V H + ++ G + ++G G R F+ D+A++ + Sbjct: 183 GPRESHKGRMASVA---FHNFNQFRAEGK-VKLFGEYSGYGPGEQTRDFVSVEDVAKVNL 238 Query: 229 WVLREYNEVEPIILSVGEEDEVSIKEAAEAVVEAM-DFHGEVTF---------------- 271 + + + I ++G + A VV + G+ Sbjct: 239 Y--FFDHPEKSGIFNLGTGRAQPFNDIAATVVNTLRALEGQPALTLAEQVEQGLVEYVPF 296 Query: 272 -DTTKSDGQFKKTASNSKLRTYLPDFRFTPFKQAVKETCAW 311 D + Q A +KLR D F ++ V W Sbjct: 297 PDALRGKYQCFTQADQTKLRAAGYDAPFLTVQEGVDRYVRW 337 >1DB3-A nrPDB Length = 372 Score = 103 bits (256), Expect = 1e-22, Method: Composition-based stats. Identities = 50/361 (13%), Positives = 100/361 (27%), Gaps = 71/361 (19%) Query: 7 SMRILVTGGSGLVGKAIQKVVADGAGLPGEDWVFVSSKD--------------------- 45 S L+TG +G G + + + + SS + Sbjct: 1 SKVALITGVTGQDGSYLAEFLLEKGYEVHGIKRRASSFNTERVDHIYQDPHTCNPKFHLH 60 Query: 46 -ADLTDTAQTRALFEKVQPTHVIHLAAMVGGLFRNIKYNLDFWRKNVHMNDNVLHSAFEV 104 DL+DT+ + +VQP V +L AM + + + + +L + + Sbjct: 61 YGDLSDTSNLTRILREVQPDEVYNLGAM-SHVAVSFESPEYTADVDAMGTLRLLEAIRFL 119 Query: 105 GARK---VVSCLSTCIFPDKTTYPIDETMIHNGPPHNSNFGYSYAKRMIDVQNRAYFQQY 161 G K ++ ++ P E P Y+ AK Y + Y Sbjct: 120 GLEKKTRFYQASTSELYGLVQEIPQKE-----TTPFYPRSPYAVAKLYAYWITVNYRESY 174 Query: 162 GCTFTAVIPTNVFGPHDNFNIEDGHVLPGLIHKVHLAKSSGSALTVW-GTGNPRRQFIYS 220 G I N P + I + + G ++ G + R + ++ Sbjct: 175 GMYACNGILFNHESPR-----RGETFVTRKITRAIANIAQGLESCLYLGNMDSLRDWGHA 229 Query: 221 LDLAQLFIWVLREYNEVEPIILSVGEEDEVSIKEAAEAVVEAMDFHGE----------VT 270 D ++ +L + +P + + S+++ E + + Sbjct: 230 KDYVKMQWMML---QQEQPEDFVIATGVQYSVRQFVEMAAAQLGIKLRFEGTGVEEKGIV 286 Query: 271 FDTTKSDG------------QFKK---------TASNSKLRTYLPDFRFTPFKQAVKETC 309 T D + +K L ++ V E Sbjct: 287 VSVTGHDAPGVKPGDVIIAVDPRYFRPAEVETLLGDPTKAHEKLGWKPEITLREMVSEMV 346 Query: 310 A 310 A Sbjct: 347 A 347 >3SXP-A nrPDB Length = 362 Score = 94.1 bits (232), Expect = 6e-20, Method: Composition-based stats. Identities = 53/324 (16%), Positives = 100/324 (30%), Gaps = 46/324 (14%) Query: 10 ILVTGGSGLVGK----AIQK-------VVADG---------------AGLPGEDWVFVSS 43 IL+TGG+G VG Q+ VV D Sbjct: 13 ILITGGAGFVGSNLAFHFQENHPKAKVVVLDKFRSNTLFSNNRPSSLGHFKNLIGFKGEV 72 Query: 44 KDADLTDTAQTRALFEKVQPTHVIHLAAMVGGLFRNIKYNLDFWRKNVHMNDNVLHSAFE 103 AD+ + R L EK+ ++ H AA+ N + + N N+L A Sbjct: 73 IAADINNPLDLRRL-EKLHFDYLFHQAAVSDTTMLNQEL---VMKTNYQAFLNLLEIARS 128 Query: 104 VGARKVVSCLSTCIFPDKTTYPIDETMIHNGPPHNSNFGYSYAKRMIDVQNRAYFQQYGC 163 A KV+ S ++ + + + Y ++K +D Sbjct: 129 KKA-KVIYASSAGVYGNTKAPNVVGKN------ESPENVYGFSKLCMDEFV--LSHSNDN 179 Query: 164 TFTAVIPTNVFGPHDNFNIEDGHVLPGLIHKVHLAKSSGSALTVWGTGNPRRQFIYSLDL 223 + NV+GP + + + ++ ++ L + + ++ G R F+Y D+ Sbjct: 180 VQVGLRYFNVYGPREFYKEKTA----SMVLQLALGAMAFKEVKLFEFGEQLRDFVYIEDV 235 Query: 224 AQLFIWVLREYNEVEPIILSVGEEDEVSIKEAAEAVVEAMDFHGEVTFDTTKSDGQFKKT 283 Q + ++ + +VG S E + E + + Q Sbjct: 236 IQANVKAMKAQKS---GVYNVGYSQARSYNEIVSILKEHLGDFKVTYIKNPYAFFQKHTQ 292 Query: 284 ASNSKLRTYLPDFRFTPFKQAVKE 307 A L + +K+ Sbjct: 293 AHIEPTILDLDYTPLYDLESGIKD 316 >3SC6-A nrPDB Length = 287 Score = 93.3 bits (230), Expect = 1e-19, Method: Composition-based stats. Identities = 46/305 (15%), Positives = 106/305 (34%), Gaps = 38/305 (12%) Query: 9 RILVTGGSGLVGKAIQKVVADGAGLPGEDWVFVSSKD--ADLTDTAQTRALFEKVQPTHV 66 R+++TG +G +GK +Q+ + E++ D+T+ +Q + + ++++P + Sbjct: 7 RVIITGANGQLGKQLQEELN------PEEYDIYPFDKKLLDITNISQVQQVVQEIRPHII 60 Query: 67 IHLAAMVGGLFRNIKYNLDFWRKNVHMNDNVLHSAFEVGARKVVSCLSTCIFPDKTTYPI 126 IH AA + +L + N NV ++ VGA K+V + +F P Sbjct: 61 IHCAAYTKVDQAEKERDLAYV-INAIGARNVAVASQLVGA-KLVYISTDYVFQGDR--PE 116 Query: 127 DETMIHNGPPHNSNFGYSYAKRMIDVQNRAYFQQYGCTFTAVIPTNVFGPHDNFNIEDGH 186 HN Y +K + + +Y V + ++G + N Sbjct: 117 GYDEFHN---PAPINIYGASKYAGEQFVKELHNKY----FIVRTSWLYGKYGN------- 162 Query: 187 VLPGLIHKVHLAKSSGSALTVWGTGNPRRQFIYSLDLAQLFIWVLREYNEVEPIILSVGE 246 + + ++V ++ A L + + + + V Sbjct: 163 ---NFVKTMIRLGKEREEISVVADQIGSPTYV-----ADLNVMINKLIHTSLYGTYHVSN 214 Query: 247 EDEVSIKEAAEAVVEAMDFHGEVTFDTTKSDG----QFKKTASNSKLRTYLPDFRFTPFK 302 S E A+ + + V +T+ G + K + + + ++ Sbjct: 215 TGSCSWFEFAKKIFSYANMKVNVLPVSTEEFGAAAARPKYSIFQHNMLRLNGFLQMPSWE 274 Query: 303 QAVKE 307 + ++ Sbjct: 275 EGLER 279 >3WMX-A nrPDB Length = 358 Score = 91.0 bits (224), Expect = 6e-19, Method: Composition-based stats. Identities = 58/327 (17%), Positives = 105/327 (32%), Gaps = 32/327 (9%) Query: 4 PQGSM------RILVTGGSGLVGKAIQKVVADGAG---------LPGEDWVFVSSKDADL 48 P+GS +IL+ G +G +G + +A+ G +P V ++ + + Sbjct: 16 PRGSHMEAGKPKILIVGANGQIGSELALALAERYGRTNVITSDVVPTGRHVHLTHEMLNA 75 Query: 49 TDTAQTRALFEKVQPTHVIHLAAMVGGLFRNIKYNLDFWRKNVHMNDNVLHSAFEVGARK 108 TD + + E+ T V LAA + K W N+ NVL A + G + Sbjct: 76 TDRGELATVVERHGITQVYLLAAALSATGE--KAPQWAWNLNMTSLLNVLELARQTGLER 133 Query: 109 VVSCLSTCIFPDKTTYPIDETMIHNGPPHNSNFGYSYAKRMIDVQNRAYFQQYGCTFTAV 168 V S F T P +T Y +K+ + R Y +G +V Sbjct: 134 VFWPSSIAAFG--PTTPAGQT--PQKTVMEPTTVYGISKQAGEGWCRWYHANHGVDVRSV 189 Query: 169 IPTNVFGPHDNFNIEDGHVLPGLIHKVHLAKSSGSALTVWGTGNPRRQFIYSLDLAQLFI 228 + + H A +G T + + +Y D + I Sbjct: 190 RYPGLISHKTPPGGGTTDYAVDIFH----AAVTGEPYTCFLKEDEALPMMYMPDAIRATI 245 Query: 229 WVLREYNEV--EPIILSVGEEDEVSIKEAAEAVVEA---MDFHGEVTFDTTKSDGQFKKT 283 ++ + E ++ + + A A+ E E + + G + Sbjct: 246 ELMEAPADKLSERGSYNIA-GMSFTPAQIAAAIREQVPGFQIRYEPDYRQAIAQGWPD-S 303 Query: 284 ASNSKLRTYLPDFRFTPFKQAVKETCA 310 +S R K+ V + A Sbjct: 304 IDDSVARADWGWKAQYGLKEMVADMLA 330 >4WPG-A nrPDB Length = 289 Score = 88.3 bits (217), Expect = 4e-18, Method: Composition-based stats. Identities = 40/196 (20%), Positives = 76/196 (38%), Gaps = 13/196 (6%) Query: 10 ILVTGGSGLVGKAIQKVVADGAGLPGEDWVFVSSKDADLTDTAQTRALFEKVQPTHVIHL 69 IL+TG +G +G ++ ++ + G D+V V + D+T+ + A+F +V+PT V H Sbjct: 7 ILITGSNGQLGTELRYLLDER----GVDYVAVDVAEMDITNEDKVEAVFAQVKPTLVYHC 62 Query: 70 AAMVGGLFRNIKYNLDFWRKNVHMNDNVLHSAFEVGARKVVSCLSTCIFPDKTTYPIDET 129 AA + NV ++N+ + + GA +V + +F P+ + Sbjct: 63 AAYTAVDAAEDEGKALNEAINVTGSENIAKACGKYGAT-LVYISTDYVFDGNK--PVGQ- 118 Query: 130 MIHNGPPHNSNFGYSYAKRMIDVQNRAYFQQYGCTFTAVIPTNVFGPH-DNFNIEDGHVL 188 + Y KR+ ++ Y + F + VFG + NF + Sbjct: 119 EWVETDHPDPKTEYGRTKRLGELAVERYAEH----FYIIRTAWVFGNYGKNFVFTMEQLA 174 Query: 189 PGLIHKVHLAKSSGSA 204 + G Sbjct: 175 ENHSRLTVVNDQHGRP 190 >4J2O-A nrPDB Length = 363 Score = 87.6 bits (215), Expect = 6e-18, Method: Composition-based stats. Identities = 51/288 (17%), Positives = 94/288 (32%), Gaps = 56/288 (19%) Query: 4 PQGSM---RIL-VTGGSGLVGKAIQKVVADGAGLPGEDWVFVSSKDAD------------ 47 P+GSM ++L +TGG+G G A+ K + + K D Sbjct: 16 PRGSMFKDKVLLITGGTGSFGNAVLKRFLE-TDIKEIRIFSRDEKKQDDMRKKYHSAKLK 74 Query: 48 --LTDTAQTRALFEKVQPTHVIHLAAMVGGLFRNIKYNLDFWRKNVHMNDNVLHSAFEVG 105 + D ++ + I+ AA + + + ++ + NV +NVL +A + Sbjct: 75 FYIGDVRDYNSILNATRGVDYIYHAAALKQVPSCEFHPMEAVKTNVLGTENVLEAAIQNH 134 Query: 106 ARKVVSCLSTCIFPDKTTYPIDETMIHNGPPHNSNFGYSYAKRMIDVQNRAYFQQ-YGCT 164 ++VV C+ DK YPI +K M++ A + G Sbjct: 135 VKRVV-----CLSTDKAVYPI--------------NAMGISKAMMEKVMVAKSRNLEGLD 175 Query: 165 FTA--VIPTNVFGPHDNFNIEDGHVLPGLIHKVHLAKSSGSALTVWGTGNPRRQFIYSLD 222 NV + +I G LT+ N R + D Sbjct: 176 TVICGTRYGNVMASRGS-----------VIPLFVDQIRQGKPLTIT-DPNMTRFMMTLED 223 Query: 223 LAQLFIWVLREYNEVEPIILSVGEEDEVSIKEAAEAVVEAMDFHGEVT 270 L ++ + + V + +I AEA+ + ++ Sbjct: 224 AVDLVLYAFEHGENGD---IFVQKAPAATIAVLAEALKQLLNVEDHPI 268 >6GPK-A nrPDB Length = 373 Score = 87.6 bits (215), Expect = 6e-18, Method: Composition-based stats. Identities = 57/353 (16%), Positives = 106/353 (30%), Gaps = 64/353 (18%) Query: 7 SMR--ILVTGGSGLVGKAIQKVVADGAGLPGEDWVFVSSKD------------------- 45 SMR L+TG +G G + + + + SS + Sbjct: 22 SMRNVALITGITGQDGSYLAEFLLEKGYEVHGIVRRSSSFNTGRIEHLYKNPQAHIEGNM 81 Query: 46 ----ADLTDTAQTRALFEKVQPTHVIHLAAMVGGLFRNIKYNLDFWRKNV--HMNDNVLH 99 DLTD+ + +V+PT + +L A + I ++L + +V +L Sbjct: 82 KLHYGDLTDSTCLVKIINEVKPTEIYNLGAQ-SHVK--ISFDLAEYTADVDGVGTLRLLD 138 Query: 100 SAFEVGARKVV---SCLSTCIFPDKTTYPIDETMIHNGPPHNSNFGYSYAKRMIDVQNRA 156 + G V ++ ++ P E P Y AK Sbjct: 139 AVKTCGLINSVKFYQASTSQLYGKVQEIPQKE-----TTPFYPRSPYGAAKLYAYWIVVN 193 Query: 157 YFQQYGCTFTAVIPTNVFGPHDNFNIEDGHVLPGLIHKVHLAKSSGS-ALTVWGTGNPRR 215 + + Y I N P N + I + G G + +R Sbjct: 194 FREAYNLFAVNGILFNHESPRRGAN-----FVTRKISRSVAKIYLGQLECFSLGNLDAKR 248 Query: 216 QFIYSLDLAQLFIWVLREYNEVEPIILSVG------EEDEVSIKEAAEAVV--------- 260 + ++ D + +W++ + +E E +++ G E E S + +V Sbjct: 249 DWGHAKDYVEA-MWLMLQNDEPEDFVIATGEVHSVREFVEKSFLHIGKTIVWEGKNENEV 307 Query: 261 ----EAMDFHGEVTFDTTKSDGQFKKTASNSKLRTYLPDFRFTPFKQAVKETC 309 E H V + +K + L F + V+E Sbjct: 308 GRCKETGKVHVTVDLKYYRPTEVDFLQGDCTKAKQKLNWKPRVAFDELVREMV 360 >2Z95-A nrPDB Length = 345 Score = 87.6 bits (215), Expect = 7e-18, Method: Composition-based stats. Identities = 54/338 (15%), Positives = 103/338 (30%), Gaps = 52/338 (15%) Query: 8 MRILVTGGSGLVGKAIQKVVADGA-GLPGEDWVFVSSKD----------------ADLTD 50 R L+TG G G + K++ + + G D DL + Sbjct: 4 KRALITGIRGQDGAYLAKLLLEKGYEVYGADRRSGEFASWRLKELGIENDVKIIHMDLLE 63 Query: 51 TAQTRALFEKVQPTHVIHLAAMVGGLFRNIKYNLDFWRKNVHMNDNVLHSAFEVGA-RKV 109 + EKVQP V +LAA + + + + + +L + V K Sbjct: 64 FSNIIRTIEKVQPDEVYNLAAQ-SFVGVSFEQPILTAEVDAIGVLRILEALRTVKPDTKF 122 Query: 110 VSCLSTCIFPDKTTYPIDETMIHNGPPHNSNFGYSYAKRMIDVQNRAYFQQYGCTFTAVI 169 ++ +F P E P Y+ AK Y + Y + I Sbjct: 123 YQASTSEMFGKVQEIPQTE-----KTPFYPRSPYAVAKLFGHWITVNYREAYNMFACSGI 177 Query: 170 PTNVFGPHDNFNIEDGHVLPGLIHKVHLAKSSGSALTVWGTGNPRRQFIYSLDLAQLFIW 229 N H++ V + + + K V G N +R + Y+ + + Sbjct: 178 LFN----HESPLRGIEFVTRKITYSLARIKYGLQDKLVLGNLNAKRDWGYAPEYVEAMWL 233 Query: 230 VLREYNEVEPIILSVGEEDEVSIKEAAEAVVEAMDFH-----------------GEVTFD 272 ++ + EP + + +++E E + F G+V + Sbjct: 234 MM---QQPEPDDYVIATGETHTVREFVEKAAKIAGFDIEWVGEGINEKGIDRNTGKVIVE 290 Query: 273 TTKSDGQFK----KTASNSKLRTYLPDFRFTPFKQAVK 306 ++ + + K L T F + V+ Sbjct: 291 VSEEFFRPAEVDILVGNPEKAMKKLGWKPRTTFDELVE 328 >1N7G-A nrPDB Length = 381 Score = 87.2 bits (214), Expect = 8e-18, Method: Composition-based stats. Identities = 55/343 (16%), Positives = 100/343 (29%), Gaps = 56/343 (16%) Query: 3 EPQGSMRI-LVTGGSGLVGKAIQKVVADGAGLPGEDWVFVSSKD---------------- 45 EP+ +I L+TG +G G + + + S+ + Sbjct: 26 EPR---KIALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNK 82 Query: 46 -------ADLTDTAQTRALFEKVQPTHVIHLAA--MVGGLFRNIKYNLDFWRKNVHMNDN 96 ADLTD + R + ++P V +LAA V F Y D Sbjct: 83 ALMKLHYADLTDASSLRRWIDVIKPDEVYNLAAQSHVAVSFEIPDYTADVVAT---GALR 139 Query: 97 VLHSAFEV-----GARKVVSCLSTCIFPDKTTYPIDETMIHNGPPHNSNFGYSYAKRMID 151 +L + K S+ +F P + Y+ +K Sbjct: 140 LLEAVRSHTIDSGRTVKYYQAGSSEMFGS------TPPPQSETTPFHPRSPYAASKCAAH 193 Query: 152 VQNRAYFQQYGCTFTAVIPTNVFGPHDNFNIEDGHVLPGLIHKVHLAKSSGSALTVW-GT 210 Y + YG I N P N + I + G ++ G Sbjct: 194 WYTVNYREAYGLFACNGILFNHESPRRGEN-----FVTRKITRALGRIKVGLQTKLFLGN 248 Query: 211 GNPRRQFIYSLDLAQLFIWVLREYNEVEPIILSVGEEDEVSIKEAAEAVVEAMDFHG--- 267 R + ++ D + +L + +P V E+ +++E + + + Sbjct: 249 LQASRDWGFAGDYVEAMWLML---QQEKPDDYVVATEEGHTVEEFLDVSFGYLGLNWKDY 305 Query: 268 -EVTFDTTKSDGQFKKTASNSKLRTYLPDFRFTPFKQAVKETC 309 E+ + SK + L F++ VK Sbjct: 306 VEIDQRYFRPAEVDNLQGDASKAKEVLGWKPQVGFEKLVKMMV 348 >5UZH-A nrPDB Length = 345 Score = 86.8 bits (213), Expect = 1e-17, Method: Composition-based stats. Identities = 51/350 (14%), Positives = 103/350 (29%), Gaps = 59/350 (16%) Query: 7 SMRILVTGGSGLVGKAIQKVVADGAGLPGEDWVFVSSKD--------------------- 45 S L+TG +G G + + + + + SS + Sbjct: 1 SKVALITGITGQDGSYLAEFLLEKGYMVYGIIRRSSSFNTGRVEHLYKDIHITKAKFKLL 60 Query: 46 -ADLTDTAQTRALFEKVQPTHVIHLAAMVGGLFRNIKYNLDFWRKNVHMNDNVLHSAFEV 104 DLTDT ++ K++P + +LAA + + + + +L + Sbjct: 61 YGDLTDTGNLISIIAKIKPDEIYNLAAQ-SHVKVSFEMPEYTANVDGIGTLRLLEAIRAC 119 Query: 105 GARK---VVSCLSTCIFPDKTTYPIDETMIHNGPPHNSNFGYSYAKRMIDVQNRAYFQQY 161 G K ++ ++ P E P Y+ AK Y + Y Sbjct: 120 GLEKKTKFYQASTSELYGLVQEVPQKE-----TTPFYPRSPYACAKLYSYWIVVNYREAY 174 Query: 162 GCTFTAVIPTNVFGPHDNFNIEDGHVLPGLIHKVHLAKSSGSALTVWGTGNPRRQFIYSL 221 I N H++ V + V K G + R + ++ Sbjct: 175 NMFALNGILFN----HESIRRGPTFVTRKITMAVARIKLGLQDCLYLGNLDAERDWGHAK 230 Query: 222 DLAQLFIWVLREYNEVEPIILSVGEEDEVSIKEAAE----AVVEAMDFHGEVTFDTT--- 274 D + +L + +P V ++ S++E E + + +++ GE Sbjct: 231 DYVEAMWLML---QQEQPRDFCVATGEKHSVREFVEKAFACIGQTVEWKGERGTVEEHGV 287 Query: 275 --------------KSDGQFKKTASNSKLRTYLPDFRFTPFKQAVKETCA 310 + + + T L R F++ V+ Sbjct: 288 VDGVVRVRVDPRYFRPTEVDQLLGDPTLAETVLGWKRKVSFEELVRGMVE 337 >1WVG-A nrPDB Length = 359 Score = 86.4 bits (212), Expect = 1e-17, Method: Composition-based stats. Identities = 56/339 (16%), Positives = 108/339 (31%), Gaps = 45/339 (13%) Query: 8 MRILVTGGSGLVGK----------AIQKVVADGAGLPGEDWVFVSSKD------ADLTDT 51 R+ VTG +G G AI K A A + V D D+ D Sbjct: 10 KRVFVTGHTGFKGSWLSLWLTEMGAIVKGYALDAPTVPSLFEIVRLNDLMESHIGDIRDF 69 Query: 52 AQTRALFEKVQPTHVIHLAAMVGGLFRNIKYNLDFWRKNVHMNDNVLHSAFEVGARK-VV 110 + R+ + +P V H+AA + + + + + NV ++L + +VG K VV Sbjct: 70 EKLRSSIAEFKPEIVFHMAAQP-LVRLSYEQPIKTYSTNVMGTVHLLETVKQVGNIKAVV 128 Query: 111 SCLSTCIFPDKTTYPIDETMIHNGPPHNSNFGYSYAKRMIDVQNRAY---------FQQY 161 + S + ++ N P YS +K ++ A+ ++Q+ Sbjct: 129 NITSDKCYDNR---EWVWGYRENEPMGG-YDPYSNSKGCAELVASAFRNSFFNPANYEQH 184 Query: 162 GCTFTAVIPTNVFGPHDNFNIEDGHVLPGLIHKVHLAKSSGSALTVWGTGNPRRQFIYSL 221 G +V NV G + ++P ++ + + R + + L Sbjct: 185 GVGLASVRAGNVIG---GGDWAKDRLIPDILRSF-----ENNQQVIIRNPYSIRPWQHVL 236 Query: 222 DLAQLFIWVLREYNEVE---PIILSVG--EEDEVSIKEAAEAVVEAMDFHGEVTFDTTKS 276 + +I V + + G +ED +++ + +V D Sbjct: 237 EPLSGYIVVAQRLYTEGAKFSEGWNFGPRDEDAKTVEFIVDKMVTLWGDDASWLLDGENH 296 Query: 277 DGQFKKT-ASNSKLRTYLPDFRFTPFKQAVKETCAWFTD 314 + SK L + + W Sbjct: 297 PHEAHYLKLDCSKANMQLGWHPRWGLTETLSRIVKWHKA 335 >1RPN-A nrPDB Length = 335 Score = 84.5 bits (207), Expect = 5e-17, Method: Composition-based stats. Identities = 47/329 (14%), Positives = 101/329 (30%), Gaps = 37/329 (11%) Query: 6 GSM--RILVTGGSGLVGKAIQKVVADGAGLPGEDWVFVSS-----------------KDA 46 GSM LVTG +G G + K++ + SS +D Sbjct: 11 GSMTRSALVTGITGQDGAYLAKLLLEKGYRVHGLVARRSSDTRWRLRELGIEGDIQYEDG 70 Query: 47 DLTDTAQTRALFEKVQPTHVIHLAAMVGGLFRNIKYNLDFWRKNVHMNDNVLHSAFEVGA 106 D+ D + K QP V +LAA + + + + ++L + + Sbjct: 71 DMADACSVQRAVIKAQPQEVYNLAAQ-SFVGASWNQPVTTGVVDGLGVTHLLEAIRQFSP 129 Query: 107 RKVVSCLSTCIFPDKTTYPIDETMIHNGPPHNSNFGYSYAKRMIDVQNRAYFQQYGCTFT 166 ST + I P Y AK Y + +G + Sbjct: 130 ETRFYQASTS----EMFGLIQAERQDENTPFYPRSPYGVAKLYGHWITVNYRESFGLHAS 185 Query: 167 AVIPTNVFGPHDNFNIEDGHVLPGLIHKVHLAKSSGSALTV-WGTGNPRRQFIYSLDLAQ 225 + I N P + + + G + G + +R + ++ D + Sbjct: 186 SGILFNHESP-----LRGIEFVTRKVTDAVARIKLGKQQELRLGNVDAKRDWGFAGDYVE 240 Query: 226 LFIWVLREYNEVEPIILSVGEEDEVSIKEAAEAVVE--AMDFHGEVTFDTT--KSDGQFK 281 +W++ + ++ + V ++++ + E +D+ + D + Sbjct: 241 A-MWLMLQQDKADD--YVVATGVTTTVRDMCQIAFEHVGLDYRDFLKIDPAFFRPAEVDV 297 Query: 282 KTASNSKLRTYLPDFRFTPFKQAVKETCA 310 + +K + L T + ++ Sbjct: 298 LLGNPAKAQRVLGWKPRTSLDELIRMMVE 326 >4R1T-A nrPDB Length = 337 Score = 81.8 bits (200), Expect = 4e-16, Method: Composition-based stats. Identities = 66/326 (20%), Positives = 104/326 (31%), Gaps = 49/326 (15%) Query: 10 ILVTGGSGLVGKAIQKVVADGAGLPGEDWVF------------------VSSKDADLTDT 51 + VTG G + + K++ + ++ ADL D Sbjct: 13 VCVTGAGGFIASWLVKILLEKGYTVRGTVRNPDDPKNGHLRELEGAKERLTLCKADLLDY 72 Query: 52 AQTRALFEKVQPTHVIHLAAMVGGLFRNIKYNLDFWRKNVHMNDNVLHSAFEVGARKVVS 111 R V H A+ V + V NV+++A E R+VV Sbjct: 73 QSLREAINGCDG--VFHTASPVTDDPEQMVEPA------VIGTKNVINAAAEANVRRVVF 124 Query: 112 CLST-CIFPDKTTYP---IDETMIHNGP-PHNSNFGYSYAKRMIDVQNRAYFQQYGCTFT 166 S ++ D P +DET + N+ Y Y K + + ++ G Sbjct: 125 TSSIGAVYMDPNRDPETVVDETCWSDPDFCKNTKNWYCYGKMVAEQAAWEEAKEKGVDLV 184 Query: 167 AVIPTNVFGPHDNFNIEDGHVLPGLIHKVHLAKSSGSALTVWGTGNPRRQFIYSLDLAQL 226 + P V GP + + L +GSA + ++ D+A Sbjct: 185 VINPVLVQGPLLQTTVNASVL-------HILKYLTGSA-KTYANSVQA--YVDVKDVALA 234 Query: 227 FIWVLREYNEVEPIILSVGEEDEVSIKEAAEAVVEAMDFHGEVTF--DTTKSDGQFKKTA 284 I L E E L E + + E + + + T D TK + Sbjct: 235 HIL-LYETPEASGRYLC--AESVLHRGDVVEILSKFFPEYPIPTKCSDVTKPRVKP-YKF 290 Query: 285 SNSKLRTYLPDFRFTPFKQAVKETCA 310 SN KL L FTP KQ + ET Sbjct: 291 SNQKL-KDLG-LEFTPVKQCLYETVK 314 >1RKX-A nrPDB Length = 357 Score = 81.4 bits (199), Expect = 5e-16, Method: Composition-based stats. Identities = 52/337 (15%), Positives = 102/337 (30%), Gaps = 45/337 (13%) Query: 8 MRILVTGGSGLVGKAIQKVVAD-GAGLPGEDWVF---------------VSSKDADLTDT 51 R+ VTG +G G + + GA + G + S+ D+ D Sbjct: 10 KRVFVTGHTGFKGGWLSLWLQTMGATVKGYSLTAPTVPSLFETARVADGMQSEIGDIRDQ 69 Query: 52 AQTRALFEKVQPTHVIHLAAMVGGLFRNIKYNLDFWRKNVHMNDNVLHSAFEV-GARKVV 110 + + QP V H+AA + + ++ + NV +L + V G + VV Sbjct: 70 NKLLESIREFQPEIVFHMAAQP-LVRLSYSEPVETYSTNVMGTVYLLEAIRHVGGVKAVV 128 Query: 111 SCLSTCIFPDKTTYPIDETMIHNGPPHNSNFGYSYAKRMIDVQNRAYFQQYGCTFTAVIP 170 + S + +K N YS +K ++ +Y + P Sbjct: 129 NITSDKCYDNK---EWIWGYRENEAMGG-YDPYSNSKGCAELVTSSYRNSF------FNP 178 Query: 171 TNVFGPH---------DNFNIEDGHVLPGLIHKVHLAKSSGSALTVWGTGNPRRQFIYSL 221 N +G H N L ++ + A S + + R + + L Sbjct: 179 AN-YGQHGTAVATVRAGNVIGGGDWALDRIVPDILRA-FEQSQPVIIRNPHAIRPWQHVL 236 Query: 222 DLAQLFIWVLREYNEVEPII---LSVG--EEDEVSIKEAAEAVVEAMDFHGEVTFDTTKS 276 + ++ + ++ + G + D +K E +V+ D Sbjct: 237 EPLSGYLLLAQKLYTDGAEYAEGWNFGPNDADATPVKNIVEQMVKYWGEGASWQLDGNAH 296 Query: 277 DGQFKKT-ASNSKLRTYLPDFRFTPFKQAVKETCAWF 312 + SK + L ++ W Sbjct: 297 PHEAHYLKLDCSKAKMQLGWHPRWNLNTTLEYIVGWH 333 >4G5H-A nrPDB Length = 363 Score = 81.0 bits (198), Expect = 6e-16, Method: Composition-based stats. Identities = 56/307 (18%), Positives = 102/307 (33%), Gaps = 64/307 (20%) Query: 4 PQGS------MRILVTGGSGLVGKAIQKVVADGAGLPGEDWVFVSSKD------------ 45 P+GS +L+TGG+G G A+ K D + + K Sbjct: 16 PRGSAMGFDDKILLITGGTGSFGNAVMKRFLD-SNIKEIRIFSRDEKKQDDIRKKYNNSK 74 Query: 46 -----ADLTDTAQTRALFEKVQPTHVIHLAAMVGGLFRNIKYNLDFWRKNVHMNDNVLHS 100 D+ D+ +V H AA+ + + ++ + N+ +NVL S Sbjct: 75 LKFYIGDVRDSQSVETAMR--DVDYVFHAAAL-KQVPSCEFFPVEAVKTNIIGTENVLQS 131 Query: 101 AFEVGARKVVSCLSTCIFPDKTTYPIDETMIHNGPPHNSNFGYSYAKRMIDVQNRAYF-- 158 A +KV+ C+ DK YPI +K M++ A Sbjct: 132 AIHQNVKKVI-----CLSTDKAAYPI--------------NAMGISKAMMEKVFVAKSRN 172 Query: 159 -QQYGCTFTAVIPTNVFGPHDNFNIEDGHVLPGLIHKVHLAKSSGSALTVWGTGNPRRQF 217 + NV G V+P I K+ +G LT+ + R Sbjct: 173 IRSEQTLICGTRYGNVMASR-------GSVIPLFIDKIK----AGEPLTIT-DPDMTRFL 220 Query: 218 IYSLDLAQLFIWVLREYNEVEPIILSVGEEDEVSIKEAAEAVVEAMDFHGEVTFDTTKSD 277 + D +L + + E + V + ++ + A A++E + + T+ Sbjct: 221 MSLEDAVELVVHAFKH---AETGDIMVQKAPSSTVGDLATALLELFEADNAIEIIGTRHG 277 Query: 278 GQFKKTA 284 + +T Sbjct: 278 EKKAETL 284 >4KTT-E nrPDB Length = 327 Score = 80.6 bits (197), Expect = 7e-16, Method: Composition-based stats. Identities = 50/318 (15%), Positives = 97/318 (30%), Gaps = 37/318 (11%) Query: 9 RILVTGGSGLVGKAIQKVVADGAGLP---GEDWVFVSSKDADLTDTAQTRALFEKVQPTH 65 R+LVTG +GL+G+A+ K G + +L D+ + QP Sbjct: 23 RVLVTGATGLLGRAVHKEFQQNNWHAVGCGFRRARPKFEQVNLLDSNAVHHIIHDFQPHV 82 Query: 66 VIHLAAMVGGLFRNIKYNLDFWRKNVHMNDNVLHSAFEVGARKVVSCLSTCIFPDKTTYP 125 ++H AA + + + NV + N+ A VGA ++ S +F Sbjct: 83 IVHCAAERRPDVVENQPDAA-SQLNVDASGNLAKEAAAVGAF-LIYISSDYVFDG----- 135 Query: 126 IDETMIHNGPPHNSNFGYSYAKRMIDVQNRAYFQQYGCTFTAVIPTNVFGPHDNFNIEDG 185 Y K + + ++G + Sbjct: 136 -TNPPYREEDIPAPLNLYGKTKLDGEKAVLENN----LGAAVLRIPILYGEVEKLEESAV 190 Query: 186 HVLPGLIHKVHLAKSSGSALTVWGTGNPRRQFIYSLDLAQLFIWVLRE--YNEVEPIILS 243 V+ + S + + +R + D+A + + + + Sbjct: 191 TVM------FDKVQFSNKSANM--DHWQQRFPTHVKDVATVCRQLAEKRMLDPSIKGTFH 242 Query: 244 VGEEDEVSIKEAAEAVVEAMDF--------HGEVTFDTTKSDGQFKKTASNSKLRTYLPD 295 ++++ E A A+ +A + + SKL T L Sbjct: 243 WSGNEQMTKYEMACAIADAFNLPSSHLRPITDSPVLGAQRPRNA---QLDCSKLET-LGI 298 Query: 296 FRFTPFKQAVKETCAWFT 313 + TPF+ +KE+ F Sbjct: 299 GQRTPFRIGIKESLWPFL 316 >5B6K-A nrPDB Length = 366 Score = 77.9 bits (190), Expect = 6e-15, Method: Composition-based stats. Identities = 58/354 (16%), Positives = 115/354 (32%), Gaps = 52/354 (14%) Query: 4 PQGS--MRILVTGGSGLVGKAIQKVVAD---------GAGLPGEDWVFVSSKDA------ 46 P+GS + V+G +G + + + + + D + G+ V K Sbjct: 16 PRGSHMTTVFVSGATGFIAQHVVRQLLDQNYKVIGSVRSAEKGDHLKNVIFKGGDFNYEI 75 Query: 47 --DLTDTAQTRALFEKV--QPTHVIHLAAMVGGLFRNIKYNLDFWRKNVHMNDNVLHSAF 102 D++D +FEK V+H A+ +I+ +L N +L S Sbjct: 76 VKDISDPTAFDHVFEKHGKDIKVVLHTASPFHFNTTDIEKDLLIPAVN--GTKGILESIK 133 Query: 103 EVGAR---KVVSCLS--------TCIFPDKTTYPIDETMIHNGPPHNSNF----GYSYAK 147 + A+ +VV S + ++ I E + + GY +K Sbjct: 134 KYAAQTVERVVVTSSFAANTSTVDMFYAKDSSKTITEESWNQDTWESCQSDPIRGYCGSK 193 Query: 148 RMIDVQNRAYFQQY----GCTFTAVIPTNVFGPHDNFNIEDGHVLPGL-IHKVHLAKSSG 202 + + ++ + + P VFGP + + + + Sbjct: 194 KFAEKAAWDFYNANKDSVKFKLSIINPVYVFGPQNYVEPGKKILNTSSEVINSLVHLKKD 253 Query: 203 SALTVWGTGNPRRQFIYSLDLAQLFIWVLREYNEVEP-IILSVGEEDEVSIKEAA-EAVV 260 L + G+ I D+A+ I ++ +E ++L G ++ + E Sbjct: 254 DPLPEFAGGH-----IDVRDVAKAHILAFQKDELIEQRLMLHAGLFTTQTLLDIINEQFP 308 Query: 261 EAMDFHGEVTFDTTKSDGQFKKTASNSKLRTYLPDFRFTPFKQAVKETCAWFTD 314 E T D NSK + L F F K+ + +T + + Sbjct: 309 ELKGKIPAGKPGTGNPDDALT-PVDNSKTKKLLG-FEFIDLKKDLYDTISQILE 360 >2GN9-A nrPDB Length = 344 Score = 70.6 bits (171), Expect = 7e-13, Method: Composition-based stats. Identities = 43/246 (17%), Positives = 75/246 (30%), Gaps = 47/246 (19%) Query: 10 ILVTGGSGLVGKAIQKVVADGAGLPGEDWVFVSSKDAD--------------LTDTAQTR 55 IL+TGG+G GK + V D + D Sbjct: 24 ILITGGTGSFGKCFVRKVLDTTNAKKIIVYSRDELKQSEMAMEFNDPRMRFFIGDVRDLE 83 Query: 56 ALFEKVQPTHVIHLAAMVGGLFRNIKYNLDFWRKNVHMNDNVLHSAFEVGARKVVSCLST 115 L ++ + AA + + L+ + N+ NV+++ + +V++ + Sbjct: 84 RLNYALEGVDICIHAAALKHVPIAEYNPLECIKTNIMGASNVINACLKNAISQVIALST- 142 Query: 116 CIFPDKTTYPIDETMIHNGPPHNSNFGYSYAKRMIDVQNRAYFQQYG---CTFTAVIPTN 172 DK PI+ Y K D + G F+ V N Sbjct: 143 ----DKAANPINL--------------YGATKLCSDKLFVSANNFKGSSQTQFSVVRYGN 184 Query: 173 VFGPHDNFNIEDGHVLPGLIHKVHLAKSSGSALTVWGTGNPRRQFIYSLDLAQLFIWVLR 232 V G G V+P K+ K+S +T R +I + + L+ Sbjct: 185 VVGSR-------GSVVP-FFKKLVQNKASEIPIT---DIRMTRFWITLDEGVSFVLKSLK 233 Query: 233 EYNEVE 238 + E Sbjct: 234 RMHGGE 239 >5U9C-A nrPDB Length = 292 Score = 69.1 bits (167), Expect = 2e-12, Method: Composition-based stats. Identities = 39/262 (14%), Positives = 87/262 (33%), Gaps = 25/262 (9%) Query: 9 RILVTGGSGLVGKAIQKVVADGAGLPGEDWVFVSSKDADLTDTAQTRALFEKVQPTHVIH 68 +IL+TGG+G++G + + D + + +L+ + +P ++H Sbjct: 7 KILITGGTGMLGAYVTSALKDTD----YNVIVTERNTLNLSVPEAIFSYITAEKPDVILH 62 Query: 69 LAAMVGGLFRNIKYNLDFWRKNVHMNDNVLHSAFEVGARKVVSCLSTCIFPDKTTYPIDE 128 AA + N + + +A GA ++ S+ +F + +E Sbjct: 63 FAAETDVDLCEREPARAGIY-NHLATEQIAQAAKFCGAW-LLYLSSSNVFGGEGKLSYNE 120 Query: 129 TMIHNGPPHNSNFGYSYAKRMIDVQNRAYFQQYGCTFTAVIPTNVFGPHDNFNIEDGHVL 188 I Y +K + + R A G + H Sbjct: 121 LDI-----PLPMNYYGRSKLIGESSVRNACTNNHLIIRA-------GWMIGGGPDKDH-- 166 Query: 189 PGLIHKVHLAKSSGSALTVWGTGNPRRQFIYSLDLAQLFIWVLREYNEVEPIILSVGEED 248 + K+ +GS ++ + ++ L IW + + + L Sbjct: 167 -KFVGKIIQQIKAGST-SIKAVSDRLGSITSAMQLCNFIIWAINKRHT---GTLHFASSG 221 Query: 249 EVSIKEAAEAVVEAMDFHGEVT 270 +S + A A+ + ++F G++ Sbjct: 222 TISRFDIACAIGDLLNFKGDII 243 >4R1U-A nrPDB Length = 349 Score = 69.1 bits (167), Expect = 2e-12, Method: Composition-based stats. Identities = 60/322 (18%), Positives = 106/322 (32%), Gaps = 33/322 (10%) Query: 6 GSMRILVTGGSGLVGKAIQKVVADGA-GLPGEDWVFVSSKDADLTDTAQTRALFEKVQPT 64 G + VTG G + + K++ + + G K+ L + R + Sbjct: 26 GDQTVCVTGAGGFIASWLVKLLLERGYTVRGTVRNPEDPKNGHLKELEGARERLTLHKVD 85 Query: 65 --------HVIHLAAMVGGLFRNIKYNLDF-WRKNVHMNDNVLHSAFEVGARKVVSCLST 115 V+H V + N D V+ NV+ ++ E R+VV S Sbjct: 86 LLDLQSIQSVVHGCHGVFHTASPVTDNPDEMLEPAVNGTKNVIIASAEAKVRRVVFTSSI 145 Query: 116 -CIFPDKTT---YPIDETMI--HNGPPHNSNFGYSYAKRMIDVQNRAYFQQYGCTFTAVI 169 ++ D T +DE+ + N+ Y Y K + + ++ V Sbjct: 146 GTVYMDPNTSRDVVVDESYWSDLEHCKNTKNW-YCYGKTVAEQSAWDIAKENQVDLVVVN 204 Query: 170 PTNVFGPHDNFNIEDGHVLPGLIHKVHLAKSSGSALTVWGTGNPRRQFIYSLDLAQLFIW 229 P V GP I +H+ K A + +++ D+A + Sbjct: 205 PVVVLGPLLQPTINAS--------TIHILKYLNGAAKTYVNATQS--YVHVKDVALAHLL 254 Query: 230 VLREYNEVEPIILSVGEEDEVSIKEAAEAVVEAMDFHGEVTFDTTKSDGQFK-KTASNSK 288 V + I E + E E + + + T + + + + K SN K Sbjct: 255 VYETNSASGRYICC---ETALHRGEVVEILAKYFPEYPLPTKCSDEKNPRVKPYKFSNQK 311 Query: 289 LRTYLPDFRFTPFKQAVKETCA 310 L L FTP KQ + +T Sbjct: 312 L-KDLG-LEFTPVKQCLYDTVR 331 >2P4H-X nrPDB Length = 322 Score = 69.1 bits (167), Expect = 2e-12, Method: Composition-based stats. Identities = 49/311 (15%), Positives = 97/311 (31%), Gaps = 47/311 (15%) Query: 9 RILVTGGSGLVGKAIQKVVADGAGLPGEDWVFVSSKDADLTDTAQTRALFEKV------- 61 R+ VTGG+G +G I K + + + D++ EK+ Sbjct: 3 RVCVTGGTGFLGSWIIKSLLENGYSVNTTIRADPERKRDVSFLTNLPGASEKLHFFNADL 62 Query: 62 -QPTHVIHLAAMVGGLFR-NIKYNLDF---------WRKNVHMNDNVLHSAFEVG-ARKV 109 P AA+ G + + +DF ++ V +L + ++ Sbjct: 63 SNPDSF--AAAIEGCVGIFHTASPIDFAVSEPEEIVTKRTVDGALGILKACVNSKTVKRF 120 Query: 110 VSCLSTCI--FPDKTTYPIDETMIHN----GPPHNSNFGYSYAKRMIDVQNRAYFQQYGC 163 + S F K +DE+ + + Y+ +K + + + +Q G Sbjct: 121 IYTSSGSAVSFNGKDKDVLDESDWSDVDLLRSVKPFGWNYAVSKTLAEKAVLEFGEQNGI 180 Query: 164 TFTAVIPTNVFGPHDNFNIEDGHVLPGLIHKVHLAKSSGSALTVWGTGNPRRQFIYSLDL 223 +I P + + + L + G R ++ D+ Sbjct: 181 DVVTLIL-----PFIVGRFVCPKLPDSIEKALVLVLGKKEQI-----GVTRFHMVHVDDV 230 Query: 224 AQLFIWVLREYNEVEPIILSVGEEDEVSIKEAAEAVVEAMDFHGEVTFDTTK-------S 276 A+ I++L N V + V I+E ++ + + +T D K Sbjct: 231 ARAHIYLLE--NSVPGGRYNCSPFI-VPIEEMSQLLSAKYPEYQILTVDELKEIKGARLP 287 Query: 277 DGQFKKTASNS 287 D KK Sbjct: 288 DLNTKKLVDAG 298 >2GGS-A nrPDB Length = 273 Score = 68.3 bits (165), Expect = 4e-12, Method: Composition-based stats. Identities = 48/299 (16%), Positives = 95/299 (31%), Gaps = 41/299 (13%) Query: 8 MRILVTGGSGLVGKAIQKVVADGAGLPGEDWVF--VSSKDADLTDTAQTRALFEKVQPTH 65 MR L+TG SG +G + +++++ + DLTD + K +P Sbjct: 1 MRTLITGASGQLGIELSRLLSERHEVIKVYNSSEIQGGYKLDLTDFPRLEDFIIKKRPDV 60 Query: 66 VIHLAAMVGGLFRNIKYNLDFWRKNVHMNDNVLHSAFEVGARKVVSCLSTCIFPDKTTYP 125 +I+ AAM I+ + + N +++ + + +V + +F + Sbjct: 61 IINAAAMTDVDKCEIEKEKAY-KINAEAVRHIVRAGKVID-SYIVHISTDYVFDGEK--- 115 Query: 126 IDETMIHNGPPHNSNFGYSYAKRMIDVQNRAYFQQYGCTFTAVIPTNVFGPHDNFNIEDG 185 N Y +K + + Q G Sbjct: 116 ---GNYKEEDIPNPINYYGLSKLLGETFA---LQDDSLIIRTSGIFRNKG---------- 159 Query: 186 HVLPGLIHKVHLAKSSGSALTVWGTGNPRRQFIYSLDLAQLFIWVLREYNEV-EPIILSV 244 V+ G + + YS A+ + E E+ + I+ V Sbjct: 160 -----FPIYVYKTLKEGKTVFAFKG-------YYSPISARKLASAILELLELRKTGIIHV 207 Query: 245 GEEDEVSIKEAAEAVVEAMDFHGEV-TFDTTK---SDGQFKKTASNSKLRTYLPDFRFT 299 + +S E A + E + GEV D + + + + +S+ R L +T Sbjct: 208 A-GERISRFELALKIKEKFNLPGEVKEVDEVRGWIAKRPYDSSLDSSRARKILSTDFYT 265 >3HFS-A nrPDB Length = 338 Score = 67.2 bits (162), Expect = 9e-12, Method: Composition-based stats. Identities = 55/343 (16%), Positives = 106/343 (30%), Gaps = 48/343 (13%) Query: 4 PQGSMRILVTGGSGLVGKAIQKVVADGAGLPGEDWVFVSSKD------------------ 45 P G V GG+G V + K++ ++ Sbjct: 6 PIGKKTACVVGGTGFVASLLVKLLLQKGYAVNTTVRDPDNQKKVSHLLELQELGDLKIFR 65 Query: 46 ADLTDTAQTRALFEKVQPTHVIHLAAMVGGLFRNIKYNLDFWRKNVHMNDNVLHSA-FEV 104 ADLTD A V H+A V F + D + + NV+ + Sbjct: 66 ADLTDELSFEAPIAGC--DFVFHVATPV--HFASEDPENDMIKPAIQGVVNVMKACTRAK 121 Query: 105 GARKVVSCLSTCIFP----DKTTYPIDETMIHN----GPPHNSNFGYSYAKRMIDVQNRA 156 ++V+ S D T +DE + +GY +K + + Sbjct: 122 SVKRVILTSSAAAVTINQLDGTGLVVDEKNWTDIEFLTSAKPPTWGYPASKTLAEKAAWK 181 Query: 157 YFQQYGCTFTAVIPTNVFGPHDNFNIEDGHVLPGLIHKVHLAKSSGSALTVWG-TGNPRR 215 + ++ VIPT + G ++ L ++ +G+ + G G Sbjct: 182 FAEENNIDLITVIPTLMAGSSLTSDVPSSIGL-------AMSLITGNEFLINGMKGMQML 234 Query: 216 ----QFIYSLDLAQLFIWVLREYNEVEPIILSVGEEDEVSIKEAAEAVVEAMDFHGEVTF 271 + D+ + I+V + + I S+ E A+ + + + T Sbjct: 235 SGSVSIAHVEDVCRAHIFVAEKESASGRYICCAAN---TSVPELAKFLSKRYPQYKVPTD 291 Query: 272 DTTKSDGQFKKTASNSKLRTYLPDFRFTPFKQAVKETCAWFTD 314 + K S+ KL F++ ++ E+ +F Sbjct: 292 FGDFPP-KSKLIISSEKLVKEGFSFKY-GIEEIYDESVEYFKA 332 >2NNL-D nrPDB Length = 337 Score = 67.2 bits (162), Expect = 9e-12, Method: Composition-based stats. Identities = 59/331 (17%), Positives = 115/331 (34%), Gaps = 42/331 (12%) Query: 7 SMRILVTGGSGLVGKAIQ-KVVADGAGL-----------PGEDWVFVSSKDADLT----D 50 S + VTG SG +G + +++ G + + + + + LT D Sbjct: 5 SETVCVTGASGFIGSWLVMRLLERGYTVRATVRDPTNVKKVKHLLDLPKAETHLTLWKAD 64 Query: 51 TAQTRALFEKVQP-THVIHLAAMVGGLFRNIKYNLDFWRKNVHMNDNVLHSAFEVG-ARK 108 A + E ++ T V H+A F + + + + ++ S R+ Sbjct: 65 LADEGSFDEAIKGCTGVFHVA--TPMDFESKDPENEVIKPTIEGMLGIMKSCAAAKTVRR 122 Query: 109 VVSCLST-CIFPDKTTYPI-DETMIHN----GPPHNSNFGYSYAKRMIDVQNRAYFQQYG 162 +V S + + P+ DE+ + + + Y +K + + Y ++ Sbjct: 123 LVFTSSAGTVNIQEHQLPVYDESCWSDMEFCRAKKMTAWMYFVSKTLAEQAAWKYAKENN 182 Query: 163 CTFTAVIPTNVFGPHDNFNIEDGHVLPGLIHKVHLAKSSGSALTVWGTGNPRRQFIYSLD 222 F +IPT V GP + P LI + + + ++ G QF++ D Sbjct: 183 IDFITIIPTLVVGPFIM-----SSMPPSLITALSPITGNEAHYSIIRQG----QFVHLDD 233 Query: 223 LAQLFIWVLREYNEVEPIILSVGEEDEVSIKEAAEAVVEAMDFHGEVTFDTTKSDGQFKK 282 L I+ L E + E + + I + A+ + E + T + D K Sbjct: 234 LCNAHIY-LFENPKAEGRYIC--SSHDCIILDLAKMLREKYPEYNIPT-EFKGVDENLKS 289 Query: 283 TASNSKLRTYLP---DFRFTPFKQAVKETCA 310 +SK T L + +TC Sbjct: 290 VCFSSKKLTDLGFEFKYSLEDMFTGAVDTCR 320 >3RFT-A nrPDB Length = 267 Score = 65.6 bits (158), Expect = 3e-11, Method: Composition-based stats. Identities = 34/173 (19%), Positives = 63/173 (36%), Gaps = 25/173 (14%) Query: 8 MRILVTGGSGLVGKAIQKVVADGAGLPGEDWVFVSSKDADL---------TDTAQTRALF 58 R+LVTG +G +G+ +++ +A A E D D A A+ Sbjct: 4 KRLLVTGAAGQLGRVMRERLAPMA----EILRLADLSPLDPAGPNEECVQCDLADANAVN 59 Query: 59 EKVQP-THVIHLAAMVGGLFRNIKYNLDFWRK-NVHMNDNVLHSAFEVGARKVVSCLSTC 116 V ++HL + +++ + + N+ N+ +A G ++V S Sbjct: 60 AMVAGCDGIVHLGGI------SVEKPFEQILQGNIIGLYNLYEAARAHGQPRIVFASS-- 111 Query: 117 IFPDKTTYPIDETMIHNGPPHNSNFGYSYAKRMIDVQNRAYFQQYGCTFTAVI 169 YP E + + P + Y +K + R YF ++G V Sbjct: 112 -NHTIGYYPQTERLGPDVPA-RPDGLYGVSKCFGENLARMYFDKFGQETALVR 162 >1KC3-A nrPDB Length = 299 Score = 63.7 bits (153), Expect = 9e-11, Method: Composition-based stats. Identities = 40/257 (15%), Positives = 76/257 (29%), Gaps = 26/257 (10%) Query: 8 MRILVTGGSGLVGKAIQKVVADGAGLPGEDWVFVSSKDADLTDTAQTRALFEKVQPTHVI 67 M IL+ G +G VG +Q+ +A L D D ++ K++P ++ Sbjct: 1 MNILLFGKTGQVGWELQRSLAPVGNLIALDVHSKEFC-GDFSNPKGVAETVRKLRPDVIV 59 Query: 68 HLAAMVGGLFRNIKYNLDFWRKNVHMNDNVLHSAFEVGARKVVSCLSTCIFPDKTTYPID 127 + AA + + N + + +A E GA VV + +FP P Sbjct: 60 NAAAHTA-VDKAESEPELAQLLNATSVEAIAKAANETGAW-VVHYSTDYVFPGTGDIPWQ 117 Query: 128 ETMIHNGPPHNSNFGYSYAKRMIDVQNRAYFQQYGCTFTAVIPTNVFGPHDNFNIEDGHV 187 ET + Y K + + ++ + V+ N Sbjct: 118 ETDAT-----SPLNVYGKTKLAGEKALQDNCPKH----LIFRTSWVYAGKGN-------- 160 Query: 188 LPGLIHKVHLAKSSGSALTVWGT--GNPRRQFIYSLDLAQLFIWVLREYNEVEPIILSVG 245 + L+V G P + + A L + + + Sbjct: 161 --NFAKTMLRLAKERQTLSVINDQYGAPTGAELLADCTAHAIRVALNKPEVAG--LYHLV 216 Query: 246 EEDEVSIKEAAEAVVEA 262 + + A V + Sbjct: 217 AGGTTTWHDYAALVFDE 233 >4PVC-A nrPDB Length = 342 Score = 61.0 bits (146), Expect = 6e-10, Method: Composition-based stats. Identities = 49/342 (14%), Positives = 107/342 (31%), Gaps = 52/342 (15%) Query: 8 MRILVTGGSGLVGKAIQKVVADGAGLPGEDWVFVSSKDA-----------------DLTD 50 M + V+G +G + + I ++ + D++ Sbjct: 1 MSVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISK 60 Query: 51 TAQTRALFEKV--QPTHVIHLAAMVGGLFRNIKYNLDFWRKNVHMNDNVLHSAFEV---G 105 +F+K V+H A+ + + +L N +LHS + Sbjct: 61 LDAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVN--GVKGILHSIKKYAADS 118 Query: 106 ARKVVSCLS-TCIFP----DKTTYPIDETMIH----NGPPHNSNFGYSYAKRMIDVQNRA 156 +VV S +F + + +E + + Y +K+ + Sbjct: 119 VERVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAAWE 178 Query: 157 YFQ----QYGCTFTAVIPTNVFGPHDNFNIEDGHVLPG--LIHKVHLAKSSGSALTVWGT 210 + + TAV P VFGP H+ L++ + ++G Sbjct: 179 FLEENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLSPEDKIPELFGG 238 Query: 211 GNPRRQFIYSLDLAQLFIWVLREYNEVEPIILSVGEEDEVSIKEAAEAVVEAMD-FHGEV 269 +I D+A+ + ++ + + + E ++++ + + E G + Sbjct: 239 ------YIDVRDVAKAHLVAFQKRETIGQRL--IVSEARFTMQDVLDILNEDFPVLKGNI 290 Query: 270 TFDTTKSD---GQFKKTASNSKLRTYLPDFRFTPFKQAVKET 308 S T N K + L F+F K+ + +T Sbjct: 291 PVGKPGSGATHNTLGATLDNKKSKKLLG-FKFRNLKETIDDT 331 >1ZZE-A nrPDB Length = 342 Score = 56.4 bits (134), Expect = 2e-08, Method: Composition-based stats. Identities = 40/214 (18%), Positives = 78/214 (36%), Gaps = 34/214 (15%) Query: 4 PQGSMRILVTGGSGLVGKAIQKVVADGAGLPGEDWVFVSSKDADLT-----------DTA 52 P+GS+ +LVTG +G V + + + + +SK A+L +TA Sbjct: 9 PEGSL-VLVTGANGFVASHVVEQLLEHG-YKVRGTARSASKLANLQKRWDAKYPGRFETA 66 Query: 53 QTRALFEKVQPTHVIHLAAMVGGLFRNIKYNLDFWRK---NVHMNDNVLHSAFEV-GARK 108 + ++ VI AA V + + ++ + + N L +A ++ Sbjct: 67 VVEDMLKQGAYDEVIKGAAGVAHIASVVSFSNKYDEVVTPAIGGTLNALRAAAATPSVKR 126 Query: 109 VVSCLSTC-----------IFPDKTT---YPIDETM-IHNGPPHNSNFGYSYAKRMIDVQ 153 V ST I+ D+ + ID+ + P S + Y+ +K ++ Sbjct: 127 FVLTSSTVSALIPKPNVEGIYLDEKSWNLESIDKAKTLPESDPQKSLWVYAASKTEAELA 186 Query: 154 NRAYFQQYG--CTFTAVIPTNVFGPHDNFNIEDG 185 + + T AV+P G + + G Sbjct: 187 AWKFMDENKPHFTLNAVLPNYTIGTIFDPETQSG 220 >4QUK-A nrPDB Length = 319 Score = 53.3 bits (126), Expect = 1e-07, Method: Composition-based stats. Identities = 47/331 (14%), Positives = 91/331 (27%), Gaps = 46/331 (13%) Query: 10 ILVTGGSGLVGKAIQKVVADGAGLPGEDWVFVSSK-------------------DADLTD 50 + VTG SG + + +++ + A+L + Sbjct: 3 VCVTGASGYIASWLVRLLLHRGYTVKATVRDPNDPKKVDHLVKLDGAKERLQLFKANLLE 62 Query: 51 TAQTRALFEKVQPTHVIHLAAMVGGLFRNIKYNLDFWRKNVHMNDNVLH-SAFEVGARKV 109 ++ + V H A+ ++ + L + NVL+ A ++V Sbjct: 63 EGAFDSVVQGCHG--VFHTASPFYHDVKDPQAELIDPA--LKGTLNVLNSCAKSPSLKRV 118 Query: 110 VSCLS--TCIFPDKTTYP---IDETMIHNGP-PHNSNFGYSYAKRMIDVQNRAYFQQYGC 163 V S + K P +DET + SN Y + + + + ++ Sbjct: 119 VLTSSIAAVAYNGKPRTPDVVVDETWFTDADFCAKSNLWYVVSATLAEEAAWKFVKENNI 178 Query: 164 TFTAVIPTNVFGPHDNFNIEDGHVLPGLIHKVHLAKSSGSALTVWGTGNPRRQFIYSLDL 223 + P V GP + L +G+ + ++ D+ Sbjct: 179 DMVTINPAMVIGPLLQPVLNTSAAA-------ILNLINGAQTFPNASFG----WVNVKDV 227 Query: 224 AQLFIWVLREYNEVEPIILSVGEEDEVSIKEAAEAVVEAMDFHGEVTFDTTKSDGQFKKT 283 A I + L E E + E Sbjct: 228 ANAHILAYENASASGRHCL---VERVAHYSEVVRILRELYPSLQLPEKCADDKPYVPIYQ 284 Query: 284 ASNSKLRTYLPDFRFTPFKQAVKETCAWFTD 314 S K L +TP + ++KET + Sbjct: 285 VSKEK-AKSLG-LEYTPLEVSIKETVESLKE 313 >5GUP-L nrPDB Length = 377 Score = 46.0 bits (107), Expect = 2e-05, Method: Composition-based stats. Identities = 37/265 (13%), Positives = 81/265 (30%), Gaps = 44/265 (16%) Query: 12 VTGGSGLVGKAIQKVVADGAGLPGEDWVFVSSKDADLTDTAQTRALF----EKVQPT--- 64 V G +G +G+ + + + L + Sbjct: 58 VFGATGFLGRYVVNHLGRMGSQVIVPYRCEPYDTMHLRPMGDLGQIIFMEWNGKDKDSIR 117 Query: 65 -HVIHLAAMVGGLFRN-IKYNLDFWRKNVHMNDNVLHSAFEVGARKVVSCLSTCIFPDKT 122 V H ++ + R N DF V + + + E G K++ Sbjct: 118 KVVEHSNVVINLVGREWETKNFDFEDVFVKIPHAIAQVSKEAGVEKLIHIS--------- 168 Query: 123 TYPIDETMIHNGPPHNSNFGYSYAKRMIDVQNRAYFQQYGCTFTAVIPTNVFGPHDNFNI 182 H S Y +K + + + RA F T + P+++FG D F Sbjct: 169 ---------HLNADIKSPSRYLRSKAVGEKEVRAAFP----EATIIKPSDIFGREDRF-- 213 Query: 183 EDGHVLPGLIHKVHLAKSSGSALTVWGTGNPRRQFIYSLDLAQLFIWVLREYNEVEPIIL 242 L + + G L G +Q +Y +D+++ I +++ + + Sbjct: 214 --------LNYFASMRWFGGVPLISLGK-ETVKQPVYIVDVSKGIINAIKDPD-AKGKTF 263 Query: 243 SVGEEDEVSIKEAAEAVVEAMDFHG 267 + + + + + + A+ + Sbjct: 264 AFVGPNRYLLFDLVQYIF-AVAYRP 287 >5YWN-A nrPDB Length = 334 Score = 45.2 bits (105), Expect = 4e-05, Method: Composition-based stats. Identities = 53/335 (15%), Positives = 103/335 (30%), Gaps = 46/335 (13%) Query: 10 ILVTGGSGLVGKAI--------------QKVVADGAGLPGEDWVFVSSKDADLTDT--AQ 53 + V+G +G + + I + GA L S + + + A Sbjct: 5 VFVSGATGYLAQQIIALVLSKGYKVVGSVRSEEKGANLKKLYGDDFSYEVVKVLEQKGAF 64 Query: 54 TRALFEKVQPTHVIHLAAMVGGLFRNIKYNLDFWRKNVHMNDNVLHSAFEV--GARKVVS 111 AL + + T +H A+ V + + + N VL S +V +VV Sbjct: 65 DEALKKHPEVTIFLHTASPVTFEVEDTEKEILIPAIN--GTKYVLQSIKDVAPQITRVVY 122 Query: 112 CLSTCIFPDKTTYPIDETMIHNGPPHNSNF---------GYSYAKRMIDVQNRAYFQQYG 162 S + ++ + ++ Y +K+ + + +Q Sbjct: 123 TSSVVAMSVPEELGSPDVVLSEASWSSLSYEQSKTHGVLAYFGSKQFAERAAWEFVEQEK 182 Query: 163 CTF--TAVIPTNVFGPHDNFN---IEDGHVLPGLIHKVHLAKSSGSALTVWGTGNPRRQF 217 F + V P +FGP H + + L K T TG F Sbjct: 183 PNFALSTVNPVYIFGPQAKDEEVKGTLNHSAEMVNSVLKLNKDDDVPAT---TGT----F 235 Query: 218 IYSLDLAQLFIWVLREYNEVEPIILSVGEEDEVSIKEAAEAVVEAMD--FHGEVTFDTTK 275 I D+A+ E +E + L + + + + V + Sbjct: 236 IDVRDVAKAH-LAAFEKDEAKGERLLLSN-TRFNGQTLLDVVRKNFPQLADKLPVGKPHS 293 Query: 276 SDGQFKKTASNSKLRTYLPDFRFTPFKQAVKETCA 310 D K ++ K + L F + F+ +V ++ Sbjct: 294 DDFSAFKEWNDKKTKKILG-FEYFDFETSVVDSIK 327 >2NM0-A nrPDB Length = 253 Score = 42.1 bits (97), Expect = 3e-04, Method: Composition-based stats. Identities = 35/193 (18%), Positives = 64/193 (33%), Gaps = 39/193 (20%) Query: 4 PQGSMR--ILVTGGSGLVGKAIQKVVADGAGLPGEDWVFVSSKDA------DLTDTAQTR 55 P+ M +LVTGG+ +G AI + AD + + D+TDT Q Sbjct: 16 PRSHMSRSVLVTGGNRGIGLAIARAFADAGDKVAITYRSGEPPEGFLAVKCDITDTEQVE 75 Query: 56 ALFEKVQ----PTHVIHLAAMVGG----LFRNIKYNLDFWRKNVHMNDNVL----HSAFE 103 +++++ P V+ A V + + + N+ V+ + Sbjct: 76 QAYKEIEETHGPVEVLIANAGVTKDQLLMRMSEEDFTSVVETNLTGTFRVVKRANRAMLR 135 Query: 104 VGARKVVSCLSTCIFPDKTTYPIDETMIHNGPPHNSNFGYSYAKRMIDVQNRAYFQQYGC 163 +VV S + G +N Y+ +K + R+ ++ G Sbjct: 136 AKKGRVVLISSV--------------VGLLGSAGQAN--YAASKAGLVGFARSLARELGS 179 Query: 164 TFTAVIPTNVFGP 176 NV P Sbjct: 180 RNIT---FNVVAP 189 >4B4O-A nrPDB Length = 298 Score = 41.7 bits (96), Expect = 4e-04, Method: Composition-based stats. Identities = 46/267 (17%), Positives = 83/267 (31%), Gaps = 36/267 (13%) Query: 8 MRILVTGGSGLVGKAIQKVVADGAGLPGEDWVFVSSKDADLT-DTAQTRALFEKVQPTHV 66 MR+LV GG+G +G A+ +++ V +T D L Sbjct: 1 MRVLVGGGTGFIGTALTQLLNARGH--EVTLVSRKPGPGRITWDELAASGLPSC---DAA 55 Query: 67 IHLAAMVGGLFRNIKYNLDFWRKNVHMNDNVLHSAFEVGARKVVSCLSTCIFPDKTTYPI 126 ++LA NI L W N VL S E + + ++ P K + Sbjct: 56 VNLA------GENILNPLRRW--NETFQKEVLGSRLET-TQLLAKAITKAPQPPKAWVLV 106 Query: 127 DETMIHNGPP---HNSNFGYSYAKRMIDVQNRAYFQQY----GCTFTAVIPTNVFGPHDN 179 + ++ + ++ + V V G Sbjct: 107 TGVAYYQPSLTAEYDEDSPGGDFDFFSNLVTKWEAAARLPGDSTRQVVVRSGVVLGR--- 163 Query: 180 FNIEDGHVLPGLIHKVHLAKSSGSALTVWGTGNPRRQFIYSLDLAQLFIWVLREYNEVEP 239 GH+L L ++ L G + G+G+ +I+ DLA + L + Sbjct: 164 GGGAMGHML--LPFRLGL----GGPI---GSGHQFFPWIHIGDLAGILTHALEANH--VH 212 Query: 240 IILSVGEEDEVSIKEAAEAVVEAMDFH 266 +L+ + E A+ A+ Sbjct: 213 GVLNGVAPSSATNAEFAQTFGAALGRR 239 >1QYC-A nrPDB Length = 308 Score = 40.6 bits (93), Expect = 0.001, Method: Composition-based stats. Identities = 43/269 (15%), Positives = 88/269 (32%), Gaps = 35/269 (13%) Query: 9 RILVTGGSGLVGKAIQKVVADGAGLPGEDWVFVSSKDADLTDTAQTRALFEKVQPTHVIH 68 RIL+ G +G +G+ + K D + S + ++ AQ F+ +++H Sbjct: 6 RILLIGATGYIGRHVAKASLDLGH--PTFLLVRESTASSNSEKAQLLESFKA-SGANIVH 62 Query: 69 -----LAAMVGGLFRNIKYNLDFWRKNVHMNDNVLHSAFEVGARKVVSCLSTCIFPDKTT 123 A++V + + N++ + EVG K F + Sbjct: 63 GSIDDHASLVEAVKNVDVVISTVGSLQIESQVNIIKAIKEVGTVKRFFPSE---FGN--- 116 Query: 124 YPIDETMIHNGPPHNSNFGYSYAKRMIDVQNRAYFQQYGCTFTAVIPTNVFGPHDNFNIE 183 D +H P + + + + R + G +T + + N Sbjct: 117 ---DVDNVHAVEP-------AKSVFEVKAKVRRAIEAEGIPYT----------YVSSNCF 156 Query: 184 DGHVLPGLIHKVHLAKSSGSALTVWGTGNPRRQFIYSLDLAQLFIWVLREYNEVEPIILS 243 G+ L L L + + G GN R F+ D+ I + + + + Sbjct: 157 AGYFLRSLAQ-AGLTAPPRDKVVILGDGNARVVFVKEEDIGTFTIKAVDDPRTLNKTLYL 215 Query: 244 VGEEDEVSIKEAAEAVVEAMDFHGEVTFD 272 + +S+ E + +D E + Sbjct: 216 RLPANTLSLNELVALWEKKIDKTLEKAYV 244 >2V6G-A nrPDB Length = 364 Score = 39.8 bits (91), Expect = 0.002, Method: Composition-based stats. Identities = 45/276 (16%), Positives = 85/276 (30%), Gaps = 31/276 (11%) Query: 11 LVTGGSGLVGKAIQKVVADGAGLPGEDWVFVS---------SKDADL----TDTAQTRAL 57 L+ G +G++G ++ +++ A PG W +D + D + Sbjct: 5 LIVGVTGIIGNSLAEIL-PLADTPGGPWKVYGVARRTRPAWHEDNPINYVQCDISDPDDS 63 Query: 58 FEKVQPTHVIHLAAMVGGLFRNIKYNLDFWRKNVHMNDNVLHSAFEV-GARKVVSCLSTC 116 K+ P + V R+ + N M NVL + K +S + Sbjct: 64 QAKLSPLTDVTHVFYVTWANRSTEQENC--EANSKMFRNVLDAVIPNCPNLKHISLQTGR 121 Query: 117 IFPDKTTYPIDETMIHNGPPHNSNFGYSYAKRMI------DVQNRAYFQQYGCTFTAVIP 170 + H+ PP+ + K M D+ ++ G T++ P Sbjct: 122 KHYMGPFESYGKIESHD-PPYTEDLP--RLKYMNFYYDLEDIMLEEVEKKEGLTWSVHRP 178 Query: 171 TNVFG--PHDNFNIEDGHVLPGLIHKVHLAKSSGSALTVWGTGNPRRQFIYSLDLAQLFI 228 N+FG P+ N+ + I K + G + +A+ I Sbjct: 179 GNIFGFSPYSMMNLVGTLCVYAAICKHEGKVLRFTGCKAAWDGYS--DCSDADLIAEHHI 236 Query: 229 WVLREYNEVEPIILSVGEEDEVSIKEAAEAVVEAMD 264 W + +V D K + + E Sbjct: 237 WAAVDPYAKNE-AFNVSNGDVFKWKHFWKVLAEQFG 271 >4AVY-A nrPDB Length = 242 Score = 39.4 bits (90), Expect = 0.002, Method: Composition-based stats. Identities = 30/164 (18%), Positives = 56/164 (34%), Gaps = 22/164 (13%) Query: 9 RILVTGGSGLVGKAIQKVV-----------ADGAGLPGEDWVFVSSKDADLTDTAQTRAL 57 ++LVTGGS +G AI D G+ + ++ D+TD+ + + L Sbjct: 13 QVLVTGGSSGIGAAIAMQFAELGAEVVALGLDADGVHAPRHPRIRREELDITDSQRLQRL 72 Query: 58 FEKVQPTHVIHLAAMVGGLFRNIKYNLDFWRKNVHMNDNVLHSAFEVGARKVVSCLSTCI 117 FE + V+ A + Y+L + + + N+ + + + Sbjct: 73 FEALPRLDVLVNNAGISRDREE--YDLATFER--VLRLNLSAAMLASQLARPLLAQR--- 125 Query: 118 FPDKTTYPIDETMIHNGPPHNSNFGYSYAKRMIDVQNRAYFQQY 161 + I G YS +K I R+ +Y Sbjct: 126 --GGSILNIASMYSTFGSADRP--AYSASKGAIVQLTRSLACEY 165 >3PVZ-A nrPDB Length = 399 Score = 39.4 bits (90), Expect = 0.002, Method: Composition-based stats. Identities = 46/295 (15%), Positives = 89/295 (30%), Gaps = 70/295 (23%) Query: 9 RILVTGGSGLVGKAI----------------------QKVVADGAGLPGEDWVFVSSKDA 46 R LV GG+G +G+A+ ++V D G + Sbjct: 37 RFLVLGGAGSIGQAVTKEIFKRNPQKLHVVDISENNMVELVRDIRSSFGYINGDFQTFAL 96 Query: 47 DLTDTAQTRALFEKVQPTHVIHLAAMVGGLFRNIKYNLDFWR---KNVHMNDNVLHSAFE 103 D+ + Q +V++L+A+ + R+ K R NV D + + + Sbjct: 97 DIGSIEYDAFIKADGQYDYVLNLSAL-KHV-RSEKDPFTLMRMIDVNVFNTDKTIQQSID 154 Query: 104 VGARKVVSCLSTCIFPDKTTYPIDETMIHNGPPHNSNFGYSYAKRMIDVQNRAYFQQYGC 163 GA+K C+ DK P+ +KR++++ + Sbjct: 155 AGAKKYF-----CVSTDKAANPV--------------NMMGASKRIMEMFLM--RKSEEI 193 Query: 164 TFTAVIPTNV--------FGPHDNFNIEDGHVLPGLIHKVHLAKSSGSAL----TVWGTG 211 + NV G + V P I + + L ++G Sbjct: 194 AISTARFANVAFSDGSLLHGFNQRIQKNQPIVAPNDIKRYFVTPQESGELCLMSCIFGEN 253 Query: 212 NPRRQFIYSLDLAQLFI-----WVLREYNEVEPIILSVGEEDEVSIKEAAEAVVE 261 R + L + ++ ++ EDE +E A+ + Sbjct: 254 ---RDIFFPKLSEALHLISFADIAVKYLKQLGYEPHLCESEDEA--RELAKTLPA 303 >2Q4B-A nrPDB Length = 253 Score = 39.0 bits (89), Expect = 0.003, Method: Composition-based stats. Identities = 31/183 (16%), Positives = 56/183 (30%), Gaps = 39/183 (21%) Query: 10 ILVTGGSGLVGKAIQKVVADGAG--LPGEDWVFVSSKD----------ADLTDTAQTRAL 57 +LVTG SG G+ + K + +G+ + K+ D+TD Sbjct: 7 VLVTGASGRTGQIVYKKLKEGSDKFVAKGLVRSAQGKEKIGGEADVFIGDITDADSINPA 66 Query: 58 FEKVQPTHVIHLAA---------MVGGLFRNIKYNLDFWRK-NVHMNDNVLHSAFEVGAR 107 F+ + ++ A GG I + + + + N + +A G + Sbjct: 67 FQGIDALVILTSAVPKMKPGFDPTKGGRPEFIFEDGQYPEQVDWIGQKNQIDAAKVAGVK 126 Query: 108 KVVSCLST-CIFPDKTTYPIDETMIHNGPPHNSNFGYSYAKRMIDVQNRAYFQQYGCTFT 166 +V S PD + I KR + Y G +T Sbjct: 127 HIVVVGSMGGTNPDHPLNKLGNGNIL------------VWKRKAEQ----YLADSGTPYT 170 Query: 167 AVI 169 + Sbjct: 171 IIR 173 >1MLD-A nrPDB Length = 314 Score = 38.3 bits (87), Expect = 0.004, Method: Composition-based stats. Identities = 22/168 (13%), Positives = 54/168 (32%), Gaps = 17/168 (10%) Query: 9 RILVTGGSGLVGKAIQKVVADGAGLPGEDWVFVSSKDADLTDTAQTR------------A 56 ++ V G SG +G+ + ++ + + ++ D + Sbjct: 2 KVAVLGASGGIGQPLSLLLKNSPLVSRLTLYDIAHTPGVAADLSHIETRATVKGYLGPEQ 61 Query: 57 LFEKVQPTHVIHLAAMVGGLFRNIKYNLDFWRKNVHMNDNVLHSAFEVGARKVVSCLSTC 116 L + ++ V+ + A V + +L + N + + + + ++ +S Sbjct: 62 LPDCLKGCDVVVIPAGVPRKPGMTRDDL--FNTNATIVATLTAACAQHCPDAMICIIS-- 117 Query: 117 IFPDKTTYPIDETMIHNGPPHNSNFGYSYAKRMIDVQNRAYFQQYGCT 164 P +T PI + +N N + I N + G Sbjct: 118 -NPVNSTIPITAEVFKKHGVYNPNKIFGVTTLDIVRANAFVAELKGLD 164 >4WLE-A nrPDB Length = 340 Score = 38.3 bits (87), Expect = 0.004, Method: Composition-based stats. Identities = 24/180 (13%), Positives = 56/180 (31%), Gaps = 24/180 (13%) Query: 4 PQGS-------MRILVTGGSGLVGKAIQKVVADGAGLPGEDWVFVSSKDADLTDTAQTR- 55 P+GS ++ V G SG +G+ + ++ + + ++ D + Sbjct: 16 PRGSHMSAQNNAKVAVLGASGGIGQPLSLLLKNSPLVSRLTLYDIAHTPGVAADLSHIET 75 Query: 56 -----------ALFEKVQPTHVIHLAAMVGGLFRNIKYNLDFWRKNVHMNDNVLHSAFEV 104 L + ++ V+ + A V + +L + N + + + + Sbjct: 76 KAAVKGYLGPEQLPDCLKGCDVVVIPAGVPRKPGMTRDDL--FNTNATIVATLTAACAQH 133 Query: 105 GARKVVSCLSTCIFPDKTTYPIDETMIHNGPPHNSNFGYSYAKRMIDVQNRAYFQQYGCT 164 ++ P +T PI + +N N + I N + G Sbjct: 134 CPEAMI---CVIANPVNSTIPITAEVFKKHGVYNPNKIFGVTTLDIVRANTFVAELKGLD 190 >5OVL-A nrPDB Length = 300 Score = 35.6 bits (80), Expect = 0.033, Method: Composition-based stats. Identities = 34/177 (19%), Positives = 62/177 (35%), Gaps = 21/177 (11%) Query: 7 SMRILVTGGSGLVGKAIQKVVADGAGLPGEDWVFVSSKD------ADLTDTAQTRALFEK 60 S +LVTGG+ +G AI + +A + D D+TD+A F++ Sbjct: 68 SRSVLVTGGNRGIGLAIARRLAADGHKVAVTHRGSGAPDDLFGVQCDVTDSAAVDRAFKE 127 Query: 61 VQ----PTHVIHLAAMVGGLFRNIKYNLDFWRKNVHMNDNVLHSAFEVGARKVVSCLSTC 116 V+ P V+ A + ++ + + + ++ N A++ + Sbjct: 128 VEEHQGPVEVLVANAGISKDAFLMRMTEERFEEVINTNLTGAFRC----AQRASRTMQRK 183 Query: 117 IFPDKTTYPIDETMIHNGPPHNSNFGYSYAKRMIDVQNRAYFQ---QYGCTFTAVIP 170 F M G N Y+ AK + R+ + + G T V P Sbjct: 184 RFGRIIFIGSVSGMWGIGNQAN----YAAAKAGLIGMARSISRELAKAGVTANVVAP 236 >6GCS-E nrPDB Length = 375 Score = 35.2 bits (79), Expect = 0.038, Method: Composition-based stats. Identities = 32/270 (11%), Positives = 75/270 (27%), Gaps = 65/270 (24%) Query: 12 VTGGSGLVGKAIQKVVADGAGLPGEDWV---------------FVSSKDADLTDTAQTRA 56 V G +G +G + +A + V+ + DL + Sbjct: 58 VFGANGFLGSYLTAKLAKHGTTVVVPYREEMAKRHLKVTGDLGVVNFLEMDLRNLESIDE 117 Query: 57 LFEKVQPTHVIHLAAMVGGLFRN-IKYNLDFWRKNVHMNDNVLHSAFEVGARKVVSCLST 115 V H +V + R N +++ +V + + + + + Sbjct: 118 --------AVRHSDIVVNLIGREYETKNFNYYDVHVEGARRIAEAVKKHNIARYIHVS-- 167 Query: 116 CIFPDKTTYPIDETMIHNGPPHNSNFGYSYAKRMIDVQNRAYFQQYGCTF-TAVIPTNVF 174 F + P +++ K + + + + T V P +F Sbjct: 168 -AFNAEIDSP---------------SEFNHTKGLGEQVTKDI-----VPWATIVRPAPMF 206 Query: 175 GPHDNFNIEDGHVLPGLIHKVHLAKSSGSALTVWGTG-NPRRQFIYSLDLAQLFIWVLRE 233 G D K L + + S V ++ +D+A + + Sbjct: 207 GRED---------------KWFLDRMARSPCLVSANKFQETSNPVHVIDVAAALERICFD 251 Query: 234 YNEVEPIILSVGEEDEVSIKEAAEAVVEAM 263 + + + + K+ + V E + Sbjct: 252 -DSTVAQTFELYGPQKFTQKQIIDMVSETL 280 >5OVJ-A nrPDB Length = 256 Score = 35.2 bits (79), Expect = 0.039, Method: Composition-based stats. Identities = 34/177 (19%), Positives = 62/177 (35%), Gaps = 21/177 (11%) Query: 7 SMRILVTGGSGLVGKAIQKVVADGAGLPGEDWVFVSSKD------ADLTDTAQTRALFEK 60 S +LVTGG+ +G AI + +A + D D+TD+A F++ Sbjct: 24 SRSVLVTGGNRGIGLAIARRLAADGHKVAVTHRGSGAPDDLFGVQCDVTDSAAVDRAFKE 83 Query: 61 VQ----PTHVIHLAAMVGGLFRNIKYNLDFWRKNVHMNDNVLHSAFEVGARKVVSCLSTC 116 V+ P V+ A + ++ + + + ++ N A++ + Sbjct: 84 VEEHQGPVEVLVANAGISKDAFLMRMTEERFEEVINTNLTGAFRC----AQRASRTMQRK 139 Query: 117 IFPDKTTYPIDETMIHNGPPHNSNFGYSYAKRMIDVQNRAYFQ---QYGCTFTAVIP 170 F M G N Y+ AK + R+ + + G T V P Sbjct: 140 RFGRIIFIGSVSGMWGIGNQAN----YAAAKAGLIGMARSISRELAKAGVTANVVAP 192 >1QYD-A nrPDB Length = 313 Score = 34.0 bits (76), Expect = 0.087, Method: Composition-based stats. Identities = 38/270 (14%), Positives = 82/270 (30%), Gaps = 60/270 (22%) Query: 9 RILVTGGSGLVGKAIQKVVADGAGLPGEDWVFVSSKDADLTDTAQTRALFEKV------- 61 R+L+ GG+G +GK ++V L +V + D Q F+++ Sbjct: 6 RVLIVGGTGYIGK---RIVNASISLGHPTYVLFRPEVVSNIDKVQMLLYFKQLGAKLIEA 62 Query: 62 -------------QPTHVIHLAAMVGGLFRNIKYNLDFWRKNVHMNDNVLHSAFEVGARK 108 Q VI +A+ GG+ ++ ++ + E G K Sbjct: 63 SLDDHQRLVDALKQVDVVI--SALAGGV----------LSHHILEQLKLVEAIKEAGNIK 110 Query: 109 VVSCLSTCIFPDKTTYPIDETMIHNGPPHNSNFGYSYAKRMIDVQNRAYFQQYGCTFTAV 168 + PD + + I + + R + +T Sbjct: 111 RFLPSEFGMDPDIMEHALQPGSIT---------------FIDKRKVRRAIEAASIPYT-- 153 Query: 169 IPTNVFGPHDNFNIEDGHVLPGLIHKVHLAKSSGSALTVWGTGNPRRQFIYSLDLAQLFI 228 + + N+ G+ L + ++G GN + ++ D+ I Sbjct: 154 --------YVSSNMFAGYFAGSLAQLDGHMMPPRDKVLIYGDGNVKGIWVDEDDVGTYTI 205 Query: 229 WVLREYNEVEPIILSVGEEDEVSIKEAAEA 258 + + + + + +S KE + Sbjct: 206 KSIDDPQTLNKTMYIRPPMNILSQKEVIQI 235 >6G2J-P nrPDB Length = 377 Score = 33.6 bits (75), Expect = 0.12, Method: Composition-based stats. Identities = 33/243 (13%), Positives = 76/243 (31%), Gaps = 56/243 (23%) Query: 12 VTGGSGLVGKAIQKVVADGAGLPGEDWV----------------FVSSKDADLTDTAQTR 55 V G +G +G+ + + + ++ + D D R Sbjct: 58 VFGATGFLGRYVVNHLGRMGSQVIIPYRCDVYDIMHLRLMGDLGQLTFLEWDARDKDSIR 117 Query: 56 ALFEKVQPTHVIHLAAMVGGLFRNIKYNLDFWRKNVHMNDNVLHSAFEVGARKVVSCLST 115 + VI+L +G + ++ + N+ + ++ E G + + Sbjct: 118 KAVQ--HSNVVINL---IGREWETRNFDFEDVFVNI--PRAIAQASKEAGVERFIHVS-- 168 Query: 116 CIFPDKTTYPIDETMIHNGPPHNSNFGYSYAKRMIDVQNRAYFQQYGCTFTAVIPTNVFG 175 H S+ +K + + + R+ F + P+++FG Sbjct: 169 ----------------HLNASMKSSSKSLRSKAVGEKEVRSVFP----EAIIIRPSDIFG 208 Query: 176 PHDNFNIEDGHVLPGLIHKVHLAKSSGSALTVWGTGNPRRQFIYSLDLAQLFIWVLREYN 235 D F H ++ LA L G +Q +Y D+++ + ++ + Sbjct: 209 REDRF---LNHFA---NYRWFLAV----PLVSLGF-KTVKQPVYVADVSKGIVNATKDPD 257 Query: 236 EVE 238 V Sbjct: 258 AVG 260 >1OOE-A nrPDB Length = 236 Score = 33.6 bits (75), Expect = 0.12, Method: Composition-based stats. Identities = 27/171 (15%), Positives = 54/171 (31%), Gaps = 21/171 (12%) Query: 7 SMRILVTGGSGLVGKAIQKVV-ADGAGLPGEDWVFVSSKDADLT----------DTAQTR 55 S +++V GG G +G AI + +G + D D+++ + + Sbjct: 3 SGKVIVYGGKGALGSAILEFFKKNGYTVLNIDLSANDQADSNILVDGNKNWTEQEQSILE 62 Query: 56 ALFEKVQPTHVIHLAAMVGGLFRNIKYNLDFWRK-NVHMNDNVLHSAFEVGARKVVSCLS 114 +Q + V + + GG + DF + ++ + +V SA ++ Sbjct: 63 QTASSLQGSQVDGVFCVAGGWAGGSASSKDFVKNADLMIKQSVWSSA--------IAAKL 114 Query: 115 TCIFPDKTTYPIDETMIHNGPPHNSNFGYSYAKRMIDVQNRAYFQQ-YGCT 164 P S GY AK + + + G Sbjct: 115 ATTHLKPGGLLQLTGAAAAMGPTPSMIGYGMAKAAVHHLTSSLAAKDSGLP 165 >5DBI-A nrPDB Length = 374 Score = 33.3 bits (74), Expect = 0.14, Method: Composition-based stats. Identities = 45/276 (16%), Positives = 84/276 (30%), Gaps = 36/276 (13%) Query: 11 LVTGGSGLVGKAIQKVVADGAG------------LPGEDWVFVSSKDADLTDTAQTRALF 58 LV G +G+VG ++ +V+ P W+ + D + + Sbjct: 8 LVVGVTGIVGSSLAEVLKLPDTPGGPWKVYGVARRPCPVWLAKKPVEYIQCDVSDNQETI 67 Query: 59 EKVQPTHVIHLAAMVGGLFRNIKYNLDFWRKNVHMN-----DNVLHSAFEVGARKVVSCL 113 K+ P I V + KN+ + N+ H + G + Sbjct: 68 SKLSPLKDITHIFYVSWIGSEDCQTNATMFKNILNSVIPNASNLQHVCLQTGIKHYFGIF 127 Query: 114 STCIFPDKTTYPIDETMIHNGPPHNSNFGYSYAKRMIDVQNRAYFQQYG--CTFTAVIPT 171 P D + P N Y D+++ Y + T++ P Sbjct: 128 EE----GSKVVPHDSPFTEDLPRLNVPNFY------HDLEDILYEETGKNNLTWSVHRPA 177 Query: 172 NVFGPHDNFNIEDGHVLPGLIHKVHLAKSSGSALTVWGTGNPRRQFIYSLDL---AQLFI 228 VFG + V ++ + K AL G+ N + ++D A+ I Sbjct: 178 LVFG--FSPCSMMNIVSTLCVY-ATICKHENKALVYPGSKNSWNCYADAVDADLVAEHEI 234 Query: 229 WVLREYNEVEPIILSVGEEDEVSIKEAAEAVVEAMD 264 W + + +L+ D K + + E Sbjct: 235 WAAVDPK-AKNQVLNCNNGDVFKWKHIWKKLAEEFG 269 >2ZCU-A nrPDB Length = 286 Score = 32.9 bits (73), Expect = 0.17, Method: Composition-based stats. Identities = 22/153 (14%), Positives = 54/153 (35%), Gaps = 11/153 (7%) Query: 10 ILVTGGSGLVGKAIQKVVADGAGLPGEDWVFVSSKDADLTDTAQTRALFEKVQPTHVIHL 69 I +TG +G +G + + + +P V + A A + L Sbjct: 2 IAITGATGQLGHYVIESLMK--TVPASQIVAIVRNPAKAQALAAQGITVRQADYGDEAAL 59 Query: 70 AAMVGGLFRNIKYNLDFWRKNVHMNDNVLHSAFEVGARKVVSCLSTCIFPDKTTYPIDET 129 + + G+ + + + + + NV+++A G + + ++ + D + + + Sbjct: 60 TSALQGVEKLLLISSSEVGQRAPQHRNVINAAKAAGVKFIAY--TSLLHADTSPLGLADE 117 Query: 130 MI-HNGPPHNSNFGYSYAKRMIDVQNRAYFQQY 161 I +S Y+ + N Y + Y Sbjct: 118 HIETEKMLADSGIVYTLLR------NGWYSENY 144 >4I1I-A nrPDB Length = 345 Score = 32.1 bits (71), Expect = 0.36, Method: Composition-based stats. Identities = 12/29 (41%), Positives = 19/29 (65%), Gaps = 3/29 (10%) Query: 6 GSM---RILVTGGSGLVGKAIQKVVADGA 31 GSM ++ VTG +G +G A+ ++A GA Sbjct: 20 GSMSAVKVAVTGAAGQIGYALVPLIARGA 48 >5NUE-A nrPDB Length = 332 Score = 31.3 bits (69), Expect = 0.56, Method: Composition-based stats. Identities = 15/54 (27%), Positives = 24/54 (44%) Query: 9 RILVTGGSGLVGKAIQKVVADGAGLPGEDWVFVSSKDADLTDTAQTRALFEKVQ 62 R+LVTG +G +G A+ ++A G L + V + D A E + Sbjct: 7 RVLVTGAAGQIGYALVPMIARGIMLGADQPVILHMLDIPPAAEALNGVKMELID 60 >4J6F-A nrPDB Length = 382 Score = 30.9 bits (68), Expect = 0.75, Method: Composition-based stats. Identities = 21/75 (28%), Positives = 34/75 (45%), Gaps = 3/75 (4%) Query: 10 ILVTGGSGLVGKAIQKVVADGAGLPGEDWVFVSSKDADLTDTAQTRALFEKVQPTHVIHL 69 +LVTG SG VG AI ++ +P V K+A + D +A+ + Q + Sbjct: 210 VLVTGASGGVGSAIIQLARARGAVPIA--VAGPGKEAAMLDIGA-QAVVTRGQGDLAEAV 266 Query: 70 AAMVGGLFRNIKYNL 84 A GG ++ +L Sbjct: 267 EAASGGRPIDVVADL 281 >5F5N-A nrPDB Length = 289 Score = 30.6 bits (67), Expect = 0.86, Method: Composition-based stats. Identities = 18/84 (21%), Positives = 24/84 (28%), Gaps = 13/84 (15%) Query: 10 ILVTGGSGLVGKAIQKVVADGAGLPGEDWVFVSSK-------------DADLTDTAQTRA 56 ILVTG +G G A + + + DL D A RA Sbjct: 4 ILVTGATGTQGGATVRALLARGRPVRALVRDPGTDAARALAAAGVSLVTGDLNDQASLRA 63 Query: 57 LFEKVQPTHVIHLAAMVGGLFRNI 80 V + GGL + Sbjct: 64 AMADVHGVFSVQTFMTPGGLGAEL 87 >2EW8-A nrPDB Length = 249 Score = 30.6 bits (67), Expect = 1.1, Method: Composition-based stats. Identities = 14/58 (24%), Positives = 26/58 (44%), Gaps = 3/58 (5%) Query: 12 VTGGSGLVGKAIQ-KVVADGAGLPGEDWVFVSSKDADLTDTAQTRALFEK--VQPTHV 66 +TGG+ +G+AI + +GA + D V +A + + + + QP V Sbjct: 12 ITGGANGIGRAIAERFAVEGADIAIADLVPAPEAEAAIRNLGRRVLTVKCDVSQPGDV 69 >1UZM-A nrPDB Length = 247 Score = 30.6 bits (67), Expect = 1.1, Method: Composition-based stats. Identities = 20/83 (24%), Positives = 32/83 (38%), Gaps = 10/83 (12%) Query: 4 PQGSMRILVTGGSGLVGKAIQKVVADGAGLPGEDWVFVSS------KDADLTDTAQTRAL 57 P S +LVTGG+ +G AI + +A + + D+TD+ Sbjct: 12 PFVSRSVLVTGGNRGIGLAIAQRLAADGHKVAVTHRGSGAPKGLFGVEVDVTDSDAVDRA 71 Query: 58 F---EKVQ-PTHVIHLAAMVGGL 76 F E+ Q P V+ A + Sbjct: 72 FTAVEEHQGPVEVLVSNAGLSAD 94 >5KT0-A nrPDB Length = 310 Score = 30.2 bits (66), Expect = 1.1, Method: Composition-based stats. Identities = 19/132 (14%), Positives = 45/132 (34%), Gaps = 19/132 (14%) Query: 5 QGSMRILVTGGSGLVGKAIQKVVADGAGL----------------PGEDWVFVSSKDADL 48 Q + ++V G +G +G+ + K +A L GE + + Sbjct: 36 QAPIPVIVNGAAGKMGREVVKAIAQAPDLNLLGAIDSSPEHQGKDAGELAGLSEPLEVPI 95 Query: 49 TDTAQ--TRALFEKVQ-PTHVIHLAAMVGGLFRNIKYNLDFWRKNVHMNDNVLHSAFEVG 105 T+ + + + Q P VI ++ N++ + + + V + + + Sbjct: 96 TNQLEPMLGYVAGERQGPPGVIVDFTHPDSVYDNVRSAIAYGIRPVVGTTGLSPAQIQNL 155 Query: 106 ARKVVSCLSTCI 117 A + C+ Sbjct: 156 ADFAEKASTGCL 167 >2QYS-A nrPDB Length = 318 Score = 29.8 bits (65), Expect = 1.8, Method: Composition-based stats. Identities = 38/247 (15%), Positives = 72/247 (29%), Gaps = 33/247 (13%) Query: 9 RILVTGGSGLVGKAIQKVVADGAGLPGEDWVFVSSKDADLTDTAQTRALFEKVQPTHVIH 68 +IL+ GG+G +G + K SSK L + A+ K + Sbjct: 13 KILIFGGTGYIGNHMVKGSLKLGHPTYVFTRPNSSKTTLLDEFQSLGAIIVKGELDEHEK 72 Query: 69 LAAMVGGLFRNIKYNLDFWRKNVHMNDNVLHSAFEVGARKVVSCLSTCIFPDKTTYPIDE 128 L ++ + I L F + + +L + G K + D+ Sbjct: 73 LVELMKKVDVVIS-ALAFPQ--ILDQFKILEAIKVAGNIKRFLPSDFGVEEDRI------ 123 Query: 129 TMIHNGPPHNSNFGYSYAKRMIDVQNRAYFQQYGCTFTAVIPTNVFGPHDNFNIEDGHVL 188 KRMI Y T+ + + Sbjct: 124 ------NALPPFEALIERKRMIRRAIEEANIPY--TYVSANCFASY-------------- 161 Query: 189 PGLIHKVHLAKSSGSALTVWGTGNPRRQFIYSLDLAQLFIWVLREYNEVEPIILSVGEED 248 I+ + +TV+GTG + Y D+ I V + + +++ + Sbjct: 162 --FINYLLRPYDPKDEITVYGTGEAKFAMNYEQDIGLYTIKVATDPRALNRVVIYRPSTN 219 Query: 249 EVSIKEA 255 ++ E Sbjct: 220 IITQLEL 226 >3RWB-A nrPDB Length = 247 Score = 29.4 bits (64), Expect = 1.9, Method: Composition-based stats. Identities = 34/135 (25%), Positives = 53/135 (39%), Gaps = 27/135 (20%) Query: 11 LVTGGSGLVGKAI-QKVVADGAGLPGEDWVFVSSK-------------DADLTDTAQTRA 56 LVTG + +GKAI ++ ADGA + D +K AD++D +A Sbjct: 10 LVTGAAQGIGKAIAARLAADGATVIVSDINAEGAKAAAASIGKKARAIAADISDPGSVKA 69 Query: 57 LFEKVQ----PTHVIHLAAMVGGLFRNIKYNLDFWR----KNVHMNDNVLHS----AFEV 104 LF ++Q ++ A + +LD WR N+ V + Sbjct: 70 LFAEIQALTGGIDILVNNASIVPFVAWDDVDLDHWRKIIDVNLTGTFIVTRAGTDQMRAA 129 Query: 105 G-ARKVVSCLSTCIF 118 G A +V+S S F Sbjct: 130 GKAGRVISIASNTFF 144 >4UFC-A nrPDB Length = 811 Score = 29.4 bits (64), Expect = 2.1, Method: Composition-based stats. Identities = 20/128 (15%), Positives = 41/128 (32%), Gaps = 15/128 (11%) Query: 193 HKVHLAKSSGSALTVWGTGNPRRQFIYSLDLAQLFIWVLREYNEVEPIILSVGEEDEVSI 252 VH LTV G + +L L + E E ++ Sbjct: 188 PLVHKVNVQNDQLTVTCQGKEQEGLKAALRAECQIQVKTNGTLRPAGNTLQINEGTEATL 247 Query: 253 KEAAEAVVEAMDFHGEVTFDTTKSDGQFKKTASNSKLRTYLPDFRFTPFKQAVKETCAWF 312 + A ++ V + +D + + YL P+++A+K A++ Sbjct: 248 Y-----ISAATNY---VNYQDVSAD-------ESHRTSEYLKRAMQIPYEKALKNHIAYY 292 Query: 313 TDNYEQAR 320 +++ R Sbjct: 293 KKQFDRVR 300 >3UW3-A nrPDB Length = 377 Score = 29.4 bits (64), Expect = 2.2, Method: Composition-based stats. Identities = 11/41 (26%), Positives = 21/41 (51%) Query: 6 GSMRILVTGGSGLVGKAIQKVVADGAGLPGEDWVFVSSKDA 46 GSM + + G G+VG + + + + + VF S+ +A Sbjct: 3 GSMNVGLVGWRGMVGSVLMQRMQEEGDFDLIEPVFFSTSNA 43 >3WSV-A nrPDB Length = 322 Score = 29.4 bits (64), Expect = 2.2, Method: Composition-based stats. Identities = 23/141 (16%), Positives = 45/141 (31%), Gaps = 19/141 (13%) Query: 5 QGSMRILVTGGSGLVGKAIQKVVADGAGLPGEDWVFVSSKDA-----DLTDTAQTRALF- 58 + S ++++ G +G VG +I + + + V+ + A DL D Sbjct: 3 KTSRKVVIVG-TGFVGTSIAYAMINQGVANELVLIDVNQEKAEGEALDLLDGMAWGEKNV 61 Query: 59 --------EKVQPTHVIHLAAMVGGLFRNIKYNLDFWRKNVHMNDNVLHSAFEVGARKVV 110 E VI A G + + LD + N + ++ G + Sbjct: 62 SVWSGTYEECQDANLVILTA---GVNQKPGQTRLDLVKTNATITRQIVKEVMASGFDGIF 118 Query: 111 SCLSTCIFPDKTTYPIDETMI 131 S + T E+ + Sbjct: 119 VVASNPV-DILTYLTWQESGL 138 >1BDB-A nrPDB Length = 277 Score = 29.0 bits (63), Expect = 2.5, Method: Composition-based stats. Identities = 22/125 (17%), Positives = 45/125 (36%), Gaps = 22/125 (17%) Query: 10 ILVTGGSGLVGKAIQ-KVVADGAGLP-----GEDWVFVSSKDAD-----LTDTAQTRALF 58 +L+TGG+ +G+A+ + VA+GA + E + + D + D Sbjct: 8 VLITGGASGLGRALVDRFVAEGAKVAVLDKSAERLAELETDHGDNVLGIVGDVRSLED-- 65 Query: 59 EKVQPTHVIHLAAMVGGLFR--NIKYNLDFWRKNVHMNDNVLHSAFE----VGARKVVSC 112 Q A G + D+ V + + L +AF+ + + + Sbjct: 66 ---QKQAASRCVARFGKIDTLIPNAGIWDYSTALVDLPEESLDAAFDEVFHINVKGYIHA 122 Query: 113 LSTCI 117 + C+ Sbjct: 123 VKACL 127 >4TVO-A nrPDB Length = 330 Score = 29.0 bits (63), Expect = 2.9, Method: Composition-based stats. Identities = 10/52 (19%), Positives = 25/52 (48%) Query: 8 MRILVTGGSGLVGKAIQKVVADGAGLPGEDWVFVSSKDADLTDTAQTRALFE 59 +++ VTG +G +G ++ +A G+ L + + + + + A + E Sbjct: 6 LKVAVTGAAGQIGYSLLFRLASGSLLGPDRPIELRLLEIEPALQALEGVVME 57 >4FK8-A nrPDB Length = 271 Score = 29.0 bits (63), Expect = 2.9, Method: Composition-based stats. Identities = 10/46 (21%), Positives = 23/46 (50%) Query: 255 AAEAVVEAMDFHGEVTFDTTKSDGQFKKTASNSKLRTYLPDFRFTP 300 + + E + ++ VT + +++G+ ++ KL T L F+P Sbjct: 181 LGDVIREKLVYYPTVTREEFENEGRITDLIASGKLFTDLDMPPFSP 226 >3PXX-A nrPDB Length = 287 Score = 29.0 bits (63), Expect = 3.0, Method: Composition-based stats. Identities = 43/231 (18%), Positives = 70/231 (30%), Gaps = 46/231 (19%) Query: 1 MGEPQGSMRILVTGGS-GLVGKAIQKVVADGAGL------------------------PG 35 MG Q + +LVTGG+ G K+ +GA + G Sbjct: 5 MGRVQDKV-VLVTGGARGQGRSHAVKLAEEGADIILFDICHDIETNEYPLATSRDLEEAG 63 Query: 36 EDWVFVSSK----DADLTDTAQTRA-----LFEKVQPTHVIHLAA---MVGGLFRNIKYN 83 + K + D+ D A + E + V+ A + L ++ Sbjct: 64 LEVEKTGRKAYTAEVDVRDRAAVSRELANAVAEFGKLDVVVANAGICPLGAHLP--VQAF 121 Query: 84 LDFWRKNVHMNDNVLHSAFEVGARKVVSCLSTCIFPDKTTYPIDETMIHNGPPHNSNFGY 143 D + + N +H+A + + + GP GY Sbjct: 122 ADAFDVDFVGVINTVHAALPYLTSGASIITTGSVAGLIAAA---QPPGAGGPQGPGGAGY 178 Query: 144 SYAKRMID---VQNRAYFQQYGCTFTAVIPTNVFGPHDNFNIEDGHVLPGL 191 SYAK+++D +Q A + PTNV N P L Sbjct: 179 SYAKQLVDSYTLQLAAQLAPQSIRANVIHPTNVNTDMLNSAPMYRQFRPDL 229 >2YV3-A nrPDB Length = 331 Score = 28.6 bits (62), Expect = 3.5, Method: Composition-based stats. Identities = 12/36 (33%), Positives = 18/36 (50%), Gaps = 1/36 (2%) Query: 8 MRILVTGGSGLVGKAIQKVVADGAGLPGEDWVFVSS 43 MR+ V G +G VG+ I KV+ P + +S Sbjct: 1 MRVAVVGATGAVGREILKVLEAR-NFPLSELRLYAS 35 >4UUP-A nrPDB Length = 341 Score = 28.6 bits (62), Expect = 3.9, Method: Composition-based stats. Identities = 11/31 (35%), Positives = 18/31 (58%), Gaps = 3/31 (9%) Query: 1 MGEPQGSMRILVTGGSGLVGKAIQKVVADGA 31 M EP + +L+TG +G +G A+ +A G Sbjct: 1 MSEP---IHVLITGAAGQIGYALAFRIAKGD 28 >4BL3-A nrPDB Length = 640 Score = 28.6 bits (62), Expect = 4.2, Method: Composition-based stats. Identities = 9/50 (18%), Positives = 21/50 (42%) Query: 34 PGEDWVFVSSKDADLTDTAQTRALFEKVQPTHVIHLAAMVGGLFRNIKYN 83 P + + + KD ++ D + K + + G + RN+++N Sbjct: 41 PIKIYNSLGVKDINIQDRKIKKVSKNKKRVDAQYKIKTNYGNIDRNVQFN 90 >4IIV-A nrPDB Length = 267 Score = 28.2 bits (61), Expect = 4.9, Method: Composition-based stats. Identities = 10/25 (40%), Positives = 15/25 (60%) Query: 7 SMRILVTGGSGLVGKAIQKVVADGA 31 S +LVTG S +G+AI + +A Sbjct: 26 SRSVLVTGASKGIGRAIARQLAADG 50 >4UUM-A nrPDB Length = 341 Score = 28.2 bits (61), Expect = 5.1, Method: Composition-based stats. Identities = 16/68 (23%), Positives = 25/68 (36%), Gaps = 2/68 (2%) Query: 10 ILVTGGSGLVGKAIQKVVADGAGLPGEDWVFVSSKDADLTDTAQTRALFEKVQPTHVIHL 69 +L+TG +G +G + +A G G+ V++ D T E HL Sbjct: 7 VLITGAAGQIGYILSHWIASGELY-GDRQVYLHLLDIPPAMNRLTALTMELED-CAFPHL 64 Query: 70 AAMVGGLF 77 A V Sbjct: 65 AGFVATTD 72 >4E0B-A nrPDB Length = 313 Score = 28.2 bits (61), Expect = 5.1, Method: Composition-based stats. Identities = 6/25 (24%), Positives = 16/25 (64%) Query: 7 SMRILVTGGSGLVGKAIQKVVADGA 31 +M++ V G +G +G+A+ ++ + Sbjct: 3 AMKVAVIGAAGGIGQALALLLKNRL 27 >4A10-A nrPDB Length = 447 Score = 27.9 bits (60), Expect = 5.9, Method: Composition-based stats. Identities = 10/37 (27%), Positives = 17/37 (45%) Query: 10 ILVTGGSGLVGKAIQKVVADGAGLPGEDWVFVSSKDA 46 +L+ G SG +G + V +G G+P + A Sbjct: 224 VLIWGASGGLGSYAIQFVKNGGGIPVAVVSSAQKEAA 260 >3SLK-A nrPDB Length = 795 Score = 27.9 bits (60), Expect = 6.0, Method: Composition-based stats. Identities = 28/188 (14%), Positives = 54/188 (28%), Gaps = 48/188 (25%) Query: 10 ILVTGGSGLVGKAIQKVVADGAGLPGEDWVF----------------------VSSKDAD 47 +LVTGG+G +G + + + G+ V VS + D Sbjct: 533 VLVTGGTGALGAEVARHLVIERGVRNLVLVSRRGPAASGAAELVAQLTAYGAEVSLQACD 592 Query: 48 LTDTAQTRALFE----KVQPTHVIHLAA-MVGGLFRNIKYNLDF--WRKNVHMNDNVLHS 100 + D + + T V+H A + G+ ++ R V N+L Sbjct: 593 VADRETLAKVLASIPDEHPLTAVVHAAGVLDDGVSESLTVERLDQVLRPKVDGARNLLE- 651 Query: 101 AFEVGARKVVSCLSTCIFPDKTTYPIDETMIHNGPPHNSNFGYSYAKRMIDVQNRAYFQQ 160 + V+ + + Y+ A +D + Q Sbjct: 652 LIDPDVALVLFSSVSGVLGS-----------------GGQGNYAAANSFLDALAQQ-RQS 693 Query: 161 YGCTFTAV 168 G ++ Sbjct: 694 RGLPTRSL 701 >2PH3-A nrPDB Length = 245 Score = 27.9 bits (60), Expect = 6.4, Method: Composition-based stats. Identities = 41/184 (22%), Positives = 63/184 (34%), Gaps = 26/184 (14%) Query: 9 RILVTGGSGLVGKAIQ-KVVADGAGLPG---------EDWVFVSSKDADLTDTAQTRALF 58 + L+TG S +G+AI ++ DG L E+ + + L Sbjct: 3 KALITGASRGIGRAIALRLAEDGFALAIHYGQNREKAEEVAEEARRRGSPLVAVLGANLL 62 Query: 59 EKVQPTHVIHLAAMVGGLFRNIKYNLDFWRKNVH--MNDNVLHSAFEVG-------ARKV 109 E T ++H AA V G + N R + M D + E R+ Sbjct: 63 EAEAATALVHQAAEVLGGLDTLVNNAGITRDTLLVRMKDEDWEAVLEANLSAVFRTTREA 122 Query: 110 VSCLSTCIFPDKTTYPIDETMIHNGPPHNSNFGYSYAKRMIDVQNRAYFQQY---GCTFT 166 V + F I + G P +N Y +K + RA ++Y G T Sbjct: 123 VKLMMKARFGRIVN--ITSVVGILGNPGQAN--YVASKAGLIGFTRAVAKEYAQRGITVN 178 Query: 167 AVIP 170 AV P Sbjct: 179 AVAP 182 >2LDB-A nrPDB Length = 317 Score = 27.1 bits (58), Expect = 9.4, Method: Composition-based stats. Identities = 17/123 (13%), Positives = 36/123 (29%), Gaps = 18/123 (14%) Query: 6 GSMRILVTGGSGLVGKAIQKVVADGAGLPGEDWVFVSSKD--ADLTDTAQTRALF----- 58 G R++V G +G VG + + + + + D D + Sbjct: 5 GGARVVVIG-AGFVGASYVFALMNQGIADEIVLIDANESKAIGDAMDFNHGKVFAPKPVD 63 Query: 59 -------EKVQPTHVIHLAAMVGGLFRNIKYNLDFWRKNVHMNDNVLHSAFEVGARKVVS 111 + V+ A LD KN+ + +++ S G + + Sbjct: 64 IWHGDYDDCRDADLVVICAGANQKPGETR---LDLVDKNIAIFRSIVESVMASGFQGLFL 120 Query: 112 CLS 114 + Sbjct: 121 VAT 123 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.307 0.121 0.285 Lambda K H 0.267 0.0371 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 10,452,125 Number of Sequences: 36641 Number of extensions: 374515 Number of successful extensions: 1466 Number of sequences better than 10.0: 110 Number of HSP's better than 10.0 without gapping: 84 Number of HSP's successfully gapped in prelim test: 69 Number of HSP's that attempted gapping in prelim test: 1189 Number of HSP's gapped (non-prelim): 167 length of query: 321 length of database: 10,336,785 effective HSP length: 97 effective length of query: 224 effective length of database: 6,782,608 effective search space: 1519304192 effective search space used: 1519304192 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 59 (27.5 bits)