BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q13451 (457 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 5OMP-A nrPDB 937 0.0 1KT1-A nrPDB 889 0.0 3O5D-A nrPDB 541 e-154 1QZ2-A nrPDB 349 1e-96 1Q1C-A nrPDB 323 7e-89 4TW8-A nrPDB 307 6e-84 3O5E-A nrPDB 291 3e-79 4R0X-A nrPDB 250 1e-66 1ROT-A nrPDB 187 7e-48 4DRJ-A nrPDB 185 3e-47 3JXV-A nrPDB 175 3e-44 1R9H-A nrPDB 145 4e-35 6B4P-A nrPDB 119 2e-27 5HWB-A nrPDB 112 5e-25 3IHZ-A nrPDB 110 9e-25 4QT3-A nrPDB 105 5e-23 3UQI-A nrPDB 103 1e-22 5L1D-B nrPDB 102 3e-22 5T9S-F nrPDB 102 4e-22 4GIV-A nrPDB 101 6e-22 2PBC-A nrPDB 100 1e-21 2Y78-A nrPDB 100 2e-21 2ND5-A nrPDB 100 3e-21 2L2S-A nrPDB 99 3e-21 4NNR-A nrPDB 99 5e-21 2LGO-A nrPDB 99 5e-21 1YAT-A nrPDB 98 9e-21 5HUA-A nrPDB 96 3e-20 2IF4-A nrPDB 89 5e-18 5I7P-A nrPDB 84 1e-16 5I7Q-A nrPDB 84 1e-16 1IHG-A nrPDB 84 1e-16 3B7X-A nrPDB 84 2e-16 1Q6H-A nrPDB 83 2e-16 4BF8-A nrPDB 83 3e-16 5HW8-A nrPDB 80 1e-15 2MPH-A nrPDB 79 3e-15 5MGX-E nrPDB 78 1e-14 5D75-A nrPDB 76 4e-14 5B8I-C nrPDB 75 6e-14 1JVW-A nrPDB 73 3e-13 1Y0O-A nrPDB 70 2e-12 6FO1-G nrPDB 68 1e-11 4MSP-A nrPDB 63 3e-10 4DIP-A nrPDB 62 4e-10 5JJT-A nrPDB 59 4e-09 3EY6-A nrPDB 57 1e-08 2MF9-A nrPDB 56 3e-08 5JHE-A nrPDB 56 4e-08 2D9F-A nrPDB 54 1e-07 2F4E-A nrPDB 52 5e-07 1A17-A nrPDB 52 5e-07 4JA9-A nrPDB 52 6e-07 1FD9-A nrPDB 52 8e-07 2C2L-A nrPDB 49 4e-06 6H3J-B nrPDB 49 6e-06 2VCD-A nrPDB 47 1e-05 2GW1-A nrPDB 45 6e-05 5XB0-A nrPDB 44 1e-04 1IX5-A nrPDB 42 4e-04 2LKN-A nrPDB 42 7e-04 4I2W-A nrPDB 40 0.002 2Y4T-A nrPDB 37 0.019 4CGU-A nrPDB 34 0.16 5G04-F nrPDB 32 0.54 2OGG-A nrPDB 30 1.5 2KR7-A nrPDB 30 2.2 3PRB-A nrPDB 30 2.9 2Q2E-B nrPDB 29 4.4 6AF0-A nrPDB 29 4.6 3PRA-A nrPDB 29 5.0 5UDI-A nrPDB 28 5.6 5DSE-A nrPDB 28 5.7 4HOU-A nrPDB 28 5.8 4JYS-A nrPDB 28 8.6 >5OMP-A nrPDB Length = 462 Score = 937 bits (2422), Expect = 0.0, Method: Compositional matrix adjust. Identities = 457/457 (100%), Positives = 457/457 (100%) Query: 1 MTTDEGAKNNEESPTATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGK 60 MTTDEGAKNNEESPTATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGK Sbjct: 6 MTTDEGAKNNEESPTATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGK 65 Query: 61 LSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLP 120 LSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLP Sbjct: 66 LSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLP 125 Query: 121 KIPSNATLFFEIELLDFKGEDLFEDGGIIRRTKRKGEGYSNPNEGATVEIHLEGRCGGRM 180 KIPSNATLFFEIELLDFKGEDLFEDGGIIRRTKRKGEGYSNPNEGATVEIHLEGRCGGRM Sbjct: 126 KIPSNATLFFEIELLDFKGEDLFEDGGIIRRTKRKGEGYSNPNEGATVEIHLEGRCGGRM 185 Query: 181 FDCRDVAFTVGEGEDHDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAE 240 FDCRDVAFTVGEGEDHDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAE Sbjct: 186 FDCRDVAFTVGEGEDHDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAE 245 Query: 241 LIYEVTLKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEM 300 LIYEVTLKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEM Sbjct: 246 LIYEVTLKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEM 305 Query: 301 EYGLSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEA 360 EYGLSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEA Sbjct: 306 EYGLSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEA 365 Query: 361 QLLMNEFESAKGDFEKVLEVNPQNKAARLQISMCQKKAKEHNERDRRIYANMFKKFAEQD 420 QLLMNEFESAKGDFEKVLEVNPQNKAARLQISMCQKKAKEHNERDRRIYANMFKKFAEQD Sbjct: 366 QLLMNEFESAKGDFEKVLEVNPQNKAARLQISMCQKKAKEHNERDRRIYANMFKKFAEQD 425 Query: 421 AKEEANKAMGKKTSEGVTNEKGTDSQAMEEEKPEGHV 457 AKEEANKAMGKKTSEGVTNEKGTDSQAMEEEKPEGHV Sbjct: 426 AKEEANKAMGKKTSEGVTNEKGTDSQAMEEEKPEGHV 462 >1KT1-A nrPDB Length = 457 Score = 889 bits (2296), Expect = 0.0, Method: Compositional matrix adjust. Identities = 429/457 (93%), Positives = 444/457 (97%) Query: 1 MTTDEGAKNNEESPTATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGK 60 MTTDEGAKN+ +P ATVAEQGED+TSKKDRGVLKIVKRVG+GEETPMIGD+VYVHY GK Sbjct: 1 MTTDEGAKNSRGNPAATVAEQGEDVTSKKDRGVLKIVKRVGHGEETPMIGDRVYVHYNGK 60 Query: 61 LSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLP 120 L+NGKKFDSSHDRNEPFVFS+GKGQVIKAWDIGVATMKKGEICHLLCKPEYAYG+ GSLP Sbjct: 61 LANGKKFDSSHDRNEPFVFSIGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGATGSLP 120 Query: 121 KIPSNATLFFEIELLDFKGEDLFEDGGIIRRTKRKGEGYSNPNEGATVEIHLEGRCGGRM 180 KIPSNATLFFE+ELLDFKGEDL EDGGIIRRTKR+GEGYSNPNEGA V+IHLEGRCGGR+ Sbjct: 121 KIPSNATLFFEVELLDFKGEDLLEDGGIIRRTKRRGEGYSNPNEGARVQIHLEGRCGGRV 180 Query: 181 FDCRDVAFTVGEGEDHDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAE 240 FDCRDVAFTVGEGEDHDIPIGIDKALEKMQREEQCIL+LGPRYGFGEAGKPKFGIEPNAE Sbjct: 181 FDCRDVAFTVGEGEDHDIPIGIDKALEKMQREEQCILHLGPRYGFGEAGKPKFGIEPNAE 240 Query: 241 LIYEVTLKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEM 300 LIYEVTLKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKY+QAVIQYGKIVSWLEM Sbjct: 241 LIYEVTLKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYVQAVIQYGKIVSWLEM 300 Query: 301 EYGLSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEA 360 EYGLSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEA Sbjct: 301 EYGLSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEA 360 Query: 361 QLLMNEFESAKGDFEKVLEVNPQNKAARLQISMCQKKAKEHNERDRRIYANMFKKFAEQD 420 QLLMNEFESAKGDFEKVLEVNPQNKAARLQI MCQKKAKEHNERDRR YANMFKKFAEQD Sbjct: 361 QLLMNEFESAKGDFEKVLEVNPQNKAARLQIFMCQKKAKEHNERDRRTYANMFKKFAEQD 420 Query: 421 AKEEANKAMGKKTSEGVTNEKGTDSQAMEEEKPEGHV 457 AKEEANKAM KKTSEGVTNEK T S A+EEEKPEGHV Sbjct: 421 AKEEANKAMSKKTSEGVTNEKLTASHAVEEEKPEGHV 457 >3O5D-A nrPDB Length = 264 Score = 541 bits (1395), Expect = e-154, Method: Compositional matrix adjust. Identities = 260/260 (100%), Positives = 260/260 (100%) Query: 1 MTTDEGAKNNEESPTATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGK 60 MTTDEGAKNNEESPTATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGK Sbjct: 5 MTTDEGAKNNEESPTATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGK 64 Query: 61 LSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLP 120 LSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLP Sbjct: 65 LSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLP 124 Query: 121 KIPSNATLFFEIELLDFKGEDLFEDGGIIRRTKRKGEGYSNPNEGATVEIHLEGRCGGRM 180 KIPSNATLFFEIELLDFKGEDLFEDGGIIRRTKRKGEGYSNPNEGATVEIHLEGRCGGRM Sbjct: 125 KIPSNATLFFEIELLDFKGEDLFEDGGIIRRTKRKGEGYSNPNEGATVEIHLEGRCGGRM 184 Query: 181 FDCRDVAFTVGEGEDHDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAE 240 FDCRDVAFTVGEGEDHDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAE Sbjct: 185 FDCRDVAFTVGEGEDHDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAE 244 Query: 241 LIYEVTLKSFEKAKESWEMD 260 LIYEVTLKSFEKAKESWEMD Sbjct: 245 LIYEVTLKSFEKAKESWEMD 264 >1QZ2-A nrPDB Length = 336 Score = 349 bits (895), Expect = 1e-96, Method: Compositional matrix adjust. Identities = 165/315 (52%), Positives = 235/315 (74%), Gaps = 6/315 (1%) Query: 138 KGEDLFEDGGIIRRTKRKGEGYSNPNEGATVEIHLEGRCGGRMFDCRDVAFTVGEGEDHD 197 +G + EDGGIIRR + +GEGY+ PNEGA VE+ LEG ++FD R++ F +GEGE+ D Sbjct: 17 RGSHMEEDGGIIRRIQTRGEGYAKPNEGAIVEVALEGYYKDKLFDQRELRFEIGEGENLD 76 Query: 198 IPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTLKSFEKAKESW 257 +P G+++A+++M++ E I+YL P Y FG GK KF I PNAEL YE+ LKSFEKAKESW Sbjct: 77 LPYGLERAIQRMEKGEHSIVYLKPSYAFGSVGKEKFQIPPNAELKYELHLKSFEKAKESW 136 Query: 258 EMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYGLSEKESKASESFLL 317 EM+++EKLEQ+ IVKE+GTVYFK GKY QA++QY KIVSWLE E S +E++ +++ L Sbjct: 137 EMNSEEKLEQSTIVKERGTVYFKEGKYKQALLQYKKIVSWLEYESSFSNEEAQKAQALRL 196 Query: 318 AAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKV 377 A+ LNLAMC+LKL+ ++ A+E C+KAL LDS NEKGL+RRGEA L +N+FE A+ DF+KV Sbjct: 197 ASHLNLAMCHLKLQAFSAAIESCNKALELDSNNEKGLFRRGEAHLAVNDFELARADFQKV 256 Query: 378 LEVNPQNKAARLQISMCQKKAKEHNERDRRIYANMFKKFAEQDAKEEANKAMGKKTS--- 434 L++ P NKAA+ Q+++CQ++ + R++++YANMF++ AE++ K +A + G + Sbjct: 257 LQLYPNNKAAKTQLAVCQQRIRRQLAREKKLYANMFERLAEEENKAKAEASSGDHPTDTE 316 Query: 435 ---EGVTNEKGTDSQ 446 E +N G+ SQ Sbjct: 317 MKEEQKSNTAGSQSQ 331 Score = 45.1 bits (105), Expect = 7e-05, Method: Compositional matrix adjust. Identities = 37/116 (31%), Positives = 55/116 (47%), Gaps = 18/116 (15%) Query: 30 DRGVLKIVKRVGNGEETPMIGDKVYV----HYKGKLSNGKKFDSSHDRNEPFVFSLGKGQ 85 D G+++ ++ G G P G V V +YK KL FD R F +G+G+ Sbjct: 24 DGGIIRRIQTRGEGYAKPNEGAIVEVALEGYYKDKL-----FDQRELR-----FEIGEGE 73 Query: 86 VIK---AWDIGVATMKKGEICHLLCKPEYAYGSAGSLP-KIPSNATLFFEIELLDF 137 + + + M+KGE + KP YA+GS G +IP NA L +E+ L F Sbjct: 74 NLDLPYGLERAIQRMEKGEHSIVYLKPSYAFGSVGKEKFQIPPNAELKYELHLKSF 129 >1Q1C-A nrPDB Length = 280 Score = 323 bits (829), Expect = 7e-89, Method: Compositional matrix adjust. Identities = 155/260 (59%), Positives = 195/260 (75%), Gaps = 2/260 (0%) Query: 1 MTTDEGAKNNEESPTATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGK 60 MT +E + +A + +G DI+ K+D GVLK++KR G G E PMIGD+V+VHY G Sbjct: 21 MTAEEMKATESGAQSAPLPMEGVDISPKQDEGVLKVIKREGTGTEMPMIGDRVFVHYTGW 80 Query: 61 LSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLP 120 L +G KFDSS DR + F F LGKG+VIKAWDI +ATMK GE+CH+ CKPEYAYGSAGS P Sbjct: 81 LLDGTKFDSSLDRKDKFSFDLGKGEVIKAWDIAIATMKVGEVCHITCKPEYAYGSAGSPP 140 Query: 121 KIPSNATLFFEIELLDFKGEDLF--EDGGIIRRTKRKGEGYSNPNEGATVEIHLEGRCGG 178 KIP NATL FE+EL +FKGEDL EDGGIIRR + +GEGY+ PNEGA VE+ LEG Sbjct: 141 KIPPNATLVFEVELFEFKGEDLTEEEDGGIIRRIQTRGEGYAKPNEGAIVEVALEGYYKD 200 Query: 179 RMFDCRDVAFTVGEGEDHDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPN 238 ++FD R++ F +GEGE+ D+P G+++A+++M++ E I+YL P Y FG GK KF I PN Sbjct: 201 KLFDQRELRFEIGEGENLDLPYGLERAIQRMEKGEHSIVYLKPSYAFGSVGKEKFQIPPN 260 Query: 239 AELIYEVTLKSFEKAKESWE 258 AEL YE+ LKSFEKAKESWE Sbjct: 261 AELKYELHLKSFEKAKESWE 280 >4TW8-A nrPDB Length = 235 Score = 307 bits (787), Expect = 6e-84, Method: Compositional matrix adjust. Identities = 146/235 (62%), Positives = 182/235 (77%), Gaps = 2/235 (0%) Query: 21 QGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFS 80 +G DI+ K+D GVLK++KR G G E PMIGD+V+VHY G L +G KFDSS DR + F F Sbjct: 1 EGVDISPKQDEGVLKVIKREGTGTEMPMIGDRVFVHYTGWLLDGTKFDSSLDRKDKFSFD 60 Query: 81 LGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELLDFKGE 140 LGKG+VIKAWDI +ATMK GE+CH+ CKPEYAYGSAGS PKIP NATL FE+EL +FKGE Sbjct: 61 LGKGEVIKAWDIAIATMKVGEVCHITCKPEYAYGSAGSPPKIPPNATLVFEVELFEFKGE 120 Query: 141 DLF--EDGGIIRRTKRKGEGYSNPNEGATVEIHLEGRCGGRMFDCRDVAFTVGEGEDHDI 198 DL EDGGIIRR + +GEGY+ PNEGA VE+ LEG ++FD R++ F +GEGE+ D+ Sbjct: 121 DLTEEEDGGIIRRIQTRGEGYAKPNEGAIVEVALEGYYKDKLFDQRELRFEIGEGENLDL 180 Query: 199 PIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTLKSFEKA 253 P G+++A+++M++ E I+YL P Y FG GK KF I PNAEL YE+ LKSFEKA Sbjct: 181 PYGLERAIQRMEKGEHSIVYLKPSYAFGSVGKEKFQIPPNAELKYELHLKSFEKA 235 >3O5E-A nrPDB Length = 144 Score = 291 bits (746), Expect = 3e-79, Method: Compositional matrix adjust. Identities = 140/140 (100%), Positives = 140/140 (100%) Query: 1 MTTDEGAKNNEESPTATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGK 60 MTTDEGAKNNEESPTATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGK Sbjct: 5 MTTDEGAKNNEESPTATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGK 64 Query: 61 LSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLP 120 LSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLP Sbjct: 65 LSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLP 124 Query: 121 KIPSNATLFFEIELLDFKGE 140 KIPSNATLFFEIELLDFKGE Sbjct: 125 KIPSNATLFFEIELLDFKGE 144 Score = 51.6 bits (122), Expect = 7e-07, Method: Compositional matrix adjust. Identities = 39/123 (31%), Positives = 61/123 (49%), Gaps = 14/123 (11%) Query: 138 KGEDLF--EDGGIIRRTKRKGEGYSNPNEGATVEIHLEGRCG-GRMFDCRD-----VAFT 189 +GED+ +D G+++ KR G G P G V +H +G+ G+ FD F+ Sbjct: 25 QGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFS 84 Query: 190 VGEGEDHDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGK-PKFGIEPNAELIYEVTLK 248 +G+G+ + D + M++ E C L P Y +G AG PK I NA L +E+ L Sbjct: 85 LGKGQ---VIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLPK--IPSNATLFFEIELL 139 Query: 249 SFE 251 F+ Sbjct: 140 DFK 142 >4R0X-A nrPDB Length = 122 Score = 250 bits (638), Expect = 1e-66, Method: Compositional matrix adjust. Identities = 120/121 (99%), Positives = 120/121 (99%) Query: 20 EQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVF 79 EQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVF Sbjct: 2 EQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVF 61 Query: 80 SLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELLDFKG 139 SLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLP IPSNATLFFEIELLDFKG Sbjct: 62 SLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLPGIPSNATLFFEIELLDFKG 121 Query: 140 E 140 E Sbjct: 122 E 122 Score = 52.0 bits (123), Expect = 6e-07, Method: Compositional matrix adjust. Identities = 38/122 (31%), Positives = 60/122 (49%), Gaps = 12/122 (9%) Query: 138 KGEDLF--EDGGIIRRTKRKGEGYSNPNEGATVEIHLEGRCG-GRMFDCRD-----VAFT 189 +GED+ +D G+++ KR G G P G V +H +G+ G+ FD F+ Sbjct: 3 QGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFS 62 Query: 190 VGEGEDHDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTLKS 249 +G+G+ + D + M++ E C L P Y +G AG GI NA L +E+ L Sbjct: 63 LGKGQ---VIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLP-GIPSNATLFFEIELLD 118 Query: 250 FE 251 F+ Sbjct: 119 FK 120 >1ROT-A nrPDB Length = 149 Score = 187 bits (476), Expect = 7e-48, Method: Compositional matrix adjust. Identities = 87/131 (66%), Positives = 104/131 (79%) Query: 15 TATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRN 74 +A + +G DI+ K+D GVLK++KR G G ETPMIGD+V+VHY G L +G KFDSS DR Sbjct: 14 SAPLPLEGVDISPKQDEGVLKVIKREGTGTETPMIGDRVFVHYTGWLLDGTKFDSSLDRK 73 Query: 75 EPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLPKIPSNATLFFEIEL 134 + F F LGKG+VIKAWDI VATMK GE+C + CKPEYAYGSAGS PKIP NATL FE+EL Sbjct: 74 DKFSFDLGKGEVIKAWDIAVATMKVGELCRITCKPEYAYGSAGSPPKIPPNATLVFEVEL 133 Query: 135 LDFKGEDLFED 145 +FKGEDL +D Sbjct: 134 FEFKGEDLTDD 144 Score = 53.5 bits (127), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 38/113 (33%), Positives = 54/113 (47%), Gaps = 10/113 (8%) Query: 144 EDGGIIRRTKRKGEGYSNPNEGATVEIHLEG-RCGGRMFDCR-----DVAFTVGEGEDHD 197 +D G+++ KR+G G P G V +H G G FD +F +G+GE Sbjct: 28 QDEGVLKVIKREGTGTETPMIGDRVFVHYTGWLLDGTKFDSSLDRKDKFSFDLGKGE--- 84 Query: 198 IPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTLKSF 250 + D A+ M+ E C + P Y +G AG P I PNA L++EV L F Sbjct: 85 VIKAWDIAVATMKVGELCRITCKPEYAYGSAGSPP-KIPPNATLVFEVELFEF 136 >4DRJ-A nrPDB Length = 144 Score = 185 bits (470), Expect = 3e-47, Method: Compositional matrix adjust. Identities = 86/140 (61%), Positives = 105/140 (75%) Query: 1 MTTDEGAKNNEESPTATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGK 60 MT +E + +A + +G DI+ K+D GVLK++KR G G E PMIGD+V+VHY G Sbjct: 5 MTAEEMKATESGAQSAPLPMEGVDISPKQDEGVLKVIKREGTGTEMPMIGDRVFVHYTGW 64 Query: 61 LSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLP 120 L +G KFDSS DR + F F LGKG+VIKAWDI +ATMK GE+CH+ CKPEYAYGSAGS P Sbjct: 65 LLDGTKFDSSLDRKDKFSFDLGKGEVIKAWDIAIATMKVGEVCHITCKPEYAYGSAGSPP 124 Query: 121 KIPSNATLFFEIELLDFKGE 140 KIP NATL FE+EL +FKGE Sbjct: 125 KIPPNATLVFEVELFEFKGE 144 Score = 53.1 bits (126), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 38/113 (33%), Positives = 54/113 (47%), Gaps = 10/113 (8%) Query: 144 EDGGIIRRTKRKGEGYSNPNEGATVEIHLEGR-CGGRMFDCR-----DVAFTVGEGEDHD 197 +D G+++ KR+G G P G V +H G G FD +F +G+GE Sbjct: 33 QDEGVLKVIKREGTGTEMPMIGDRVFVHYTGWLLDGTKFDSSLDRKDKFSFDLGKGE--- 89 Query: 198 IPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTLKSF 250 + D A+ M+ E C + P Y +G AG P I PNA L++EV L F Sbjct: 90 VIKAWDIAIATMKVGEVCHITCKPEYAYGSAGSPP-KIPPNATLVFEVELFEF 141 >3JXV-A nrPDB Length = 356 Score = 175 bits (444), Expect = 3e-44, Method: Compositional matrix adjust. Identities = 95/218 (43%), Positives = 136/218 (62%), Gaps = 10/218 (4%) Query: 45 ETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICH 104 +TP +GD+V VHY G L +GKKFDSS DR++ F F LG+GQVIK WD G+ TMKKGE Sbjct: 25 DTPEVGDEVEVHYTGTLLDGKKFDSSRDRDDTFKFKLGQGQVIKGWDQGIKTMKKGENAL 84 Query: 105 LLCKPEYAYGSAGSLPKIPSNATLFFEIELLDFKG-EDLFEDGGIIRRTKRKGEGYSNPN 163 PE AYG +GS P IP+NATL F++ELL + D+ +DGGI ++ ++G+ + NP Sbjct: 85 FTIPPELAYGESGSPPTIPANATLQFDVELLSWTSVRDIAKDGGIFKKILKEGDKWENPK 144 Query: 164 EGATVEIHLEGRC--GGRMFDCRDVAFTVGEGEDHDIPIGIDKALEKMQREEQCILYLGP 221 + V + E R G + V FTV +G H P + KA++ M++ E+ +L + P Sbjct: 145 DPDEVFVKYEARLEDGTVVSKSEGVEFTVKDG--HLCP-ALAKAVKTMKKGEKVLLAVKP 201 Query: 222 RYGFGEAGKPKFG----IEPNAELIYEVTLKSFEKAKE 255 +YGFGE G+P G + PNA L+ ++ L S++ E Sbjct: 202 QYGFGEMGRPAAGEGGAVPPNASLVIDLELVSWKTVTE 239 Score = 105 bits (263), Expect = 3e-23, Method: Compositional matrix adjust. Identities = 73/242 (30%), Positives = 123/242 (50%), Gaps = 29/242 (11%) Query: 29 KDRGVLKIVKRVGNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVIK 88 KD G+ K + + G+ E P D+V+V Y+ +L +G + ++E F++ G + Sbjct: 125 KDGGIFKKILKEGDKWENPKDPDEVFVKYEARLEDG----TVVSKSEGVEFTVKDGHLCP 180 Query: 89 AWDIGVATMKKGEICHLLCKPEYAYG-----SAGSLPKIPSNATLFFEIELLDFKG-EDL 142 A V TMKKGE L KP+Y +G +AG +P NA+L ++EL+ +K ++ Sbjct: 181 ALAKAVKTMKKGEKVLLAVKPQYGFGEMGRPAAGEGGAVPPNASLVIDLELVSWKTVTEI 240 Query: 143 FEDGGIIRRTKRKGEGYSNPNEGATVEIHLEGRCGGRMFDCRDVAFTVGEGEDHDIPI-- 200 +D I+++ ++ EGY PNEGA V + + G+ +D + +G D P Sbjct: 241 GDDKKILKKVLKEXEGYERPNEGAVVTVKITGK-------LQDGTVFLKKGHDEQEPFEF 293 Query: 201 ---------GIDKALEKMQREEQCILYLGPRYGFGEA-GKPKFGIEPNAELIYEVTLKSF 250 G+D+A+ M++ E ++ + P Y +G K + PN+ +IYEV L SF Sbjct: 294 KTDEEAVIEGLDRAVLNMKKGEVALVTIPPEYAYGSTESKQDAIVPPNSTVIYEVELVSF 353 Query: 251 EK 252 K Sbjct: 354 VK 355 Score = 74.3 bits (181), Expect = 9e-14, Method: Compositional matrix adjust. Identities = 49/124 (39%), Positives = 64/124 (51%), Gaps = 9/124 (7%) Query: 17 TVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGKLSNGKKF-DSSHDRNE 75 TV E G+D + +LK V + G E P G V V GKL +G F HD E Sbjct: 236 TVTEIGDD------KKILKKVLKEXEGYERPNEGAVVTVKITGKLQDGTVFLKKGHDEQE 289 Query: 76 PFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLPK--IPSNATLFFEIE 133 PF F + VI+ D V MKKGE+ + PEYAYGS S +P N+T+ +E+E Sbjct: 290 PFEFKTDEEAVIEGLDRAVLNMKKGEVALVTIPPEYAYGSTESKQDAIVPPNSTVIYEVE 349 Query: 134 LLDF 137 L+ F Sbjct: 350 LVSF 353 >1R9H-A nrPDB Length = 135 Score = 145 bits (365), Expect = 4e-35, Method: Compositional matrix adjust. Identities = 71/129 (55%), Positives = 86/129 (66%), Gaps = 2/129 (1%) Query: 24 DITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGK 83 DIT KKD GVLK++K+ G G P G V VHY G L NG KFDSS DR + F F+LG+ Sbjct: 7 DITPKKDGGVLKLIKKEGQGVVKPTTGTTVKVHYVGTLENGTKFDSSRDRGDQFSFNLGR 66 Query: 84 GQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELLDFKGEDLF 143 G VIK WD+GVATM KGE+ + +Y YG AGS PKIP ATL FE+EL ++ ED+ Sbjct: 67 GNVIKGWDLGVATMTKGEVAEFTIRSDYGYGDAGSPPKIPGGATLIFEVELFEWSAEDIS 126 Query: 144 --EDGGIIR 150 DG I+R Sbjct: 127 PDRDGTILR 135 Score = 52.0 bits (123), Expect = 5e-07, Method: Compositional matrix adjust. Identities = 41/123 (33%), Positives = 61/123 (49%), Gaps = 12/123 (9%) Query: 144 EDGGIIRRTKRKGEGYSNPNEGATVEIHLEGRC-GGRMFD-CRD----VAFTVGEGEDHD 197 +DGG+++ K++G+G P G TV++H G G FD RD +F +G G + Sbjct: 12 KDGGVLKLIKKEGQGVVKPTTGTTVKVHYVGTLENGTKFDSSRDRGDQFSFNLGRG---N 68 Query: 198 IPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTLKSFEKAKESW 257 + G D + M + E + YG+G+AG P I A LI+EV L FE + E Sbjct: 69 VIKGWDLGVATMTKGEVAEFTIRSDYGYGDAGSPP-KIPGGATLIFEVEL--FEWSAEDI 125 Query: 258 EMD 260 D Sbjct: 126 SPD 128 >6B4P-A nrPDB Length = 127 Score = 119 bits (298), Expect = 2e-27, Method: Composition-based stats. Identities = 59/114 (51%), Positives = 79/114 (69%) Query: 25 ITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKG 84 I +D+ + K + G+ +E P IG KV VHY G L++GKKFDSS DR +PFVF+LGKG Sbjct: 14 IPISQDQRLKKKIITAGSSDEQPPIGSKVSVHYTGTLTSGKKFDSSLDRGQPFVFTLGKG 73 Query: 85 QVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELLDFK 138 +VI+ WD+GV +MKKGE + +YAYG+ IP+N+TL FEIELL +K Sbjct: 74 EVIRGWDLGVKSMKKGEKSYFEIPSDYAYGNNAIPGLIPANSTLMFEIELLSWK 127 >5HWB-A nrPDB Length = 115 Score = 112 bits (279), Expect = 5e-25, Method: Composition-based stats. Identities = 56/104 (53%), Positives = 68/104 (65%) Query: 32 GVLKIVKRVGNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVIKAWD 91 GV K +K GNG + P GD V +HY G+L++G KFDSS DRNEPF +G G+VIK WD Sbjct: 5 GVTKELKSPGNGVDFPKKGDFVTIHYTGRLTDGSKFDSSVDRNEPFQTQIGTGRVIKGWD 64 Query: 92 IGVATMKKGEICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELL 135 GV M GE L P+Y YG+ G P IP N+TL FE+ELL Sbjct: 65 EGVPQMSLGEKAVLTITPDYGYGARGFPPVIPGNSTLIFEVELL 108 Score = 47.4 bits (111), Expect = 2e-05, Method: Composition-based stats. Identities = 36/105 (34%), Positives = 49/105 (46%), Gaps = 6/105 (5%) Query: 147 GIIRRTKRKGEGYSNPNEGATVEIHLEGR-CGGRMFDC---RDVAFTVGEGEDHDIPIGI 202 G+ + K G G P +G V IH GR G FD R+ F G I G Sbjct: 5 GVTKELKSPGNGVDFPKKGDFVTIHYTGRLTDGSKFDSSVDRNEPFQTQIGTGRVIK-GW 63 Query: 203 DKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTL 247 D+ + +M E+ +L + P YG+G G P I N+ LI+EV L Sbjct: 64 DEGVPQMSLGEKAVLTITPDYGYGARGFPPV-IPGNSTLIFEVEL 107 >3IHZ-A nrPDB Length = 126 Score = 110 bits (276), Expect = 9e-25, Method: Compositional matrix adjust. Identities = 59/119 (49%), Positives = 75/119 (63%), Gaps = 3/119 (2%) Query: 23 EDITSKKDRGVLKIVKRVGNG--EETPMIGDKVYVHYKGKL-SNGKKFDSSHDRNEPFVF 79 E + +D GV+K + R G G E P G++V VHY GKL S+GK FDSS +RN PF F Sbjct: 7 EQVHLTEDGGVVKTILRKGEGGEENAPKKGNEVTVHYVGKLESSGKVFDSSRERNVPFKF 66 Query: 80 SLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELLDFK 138 LG+G+VIK WDI VA+M K E C + +Y YG G IP N+ L FEIEL+ F+ Sbjct: 67 HLGQGEVIKGWDICVASMTKNEKCSVRLDSKYGYGEEGCGESIPGNSVLIFEIELISFR 125 Score = 58.9 bits (141), Expect = 5e-09, Method: Compositional matrix adjust. Identities = 43/118 (36%), Positives = 66/118 (55%), Gaps = 13/118 (11%) Query: 142 LFEDGGIIRRTKRKGEG--YSNPNEGATVEIHLEGR--CGGRMFDC---RDVAFT--VGE 192 L EDGG+++ RKGEG + P +G V +H G+ G++FD R+V F +G+ Sbjct: 11 LTEDGGVVKTILRKGEGGEENAPKKGNEVTVHYVGKLESSGKVFDSSRERNVPFKFHLGQ 70 Query: 193 GEDHDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTLKSF 250 GE + G D + M + E+C + L +YG+GE G + I N+ LI+E+ L SF Sbjct: 71 GE---VIKGWDICVASMTKNEKCSVRLDSKYGYGEEGCGE-SIPGNSVLIFEIELISF 124 >4QT3-A nrPDB Length = 134 Score = 105 bits (262), Expect = 5e-23, Method: Compositional matrix adjust. Identities = 59/119 (49%), Positives = 75/119 (63%), Gaps = 3/119 (2%) Query: 23 EDITSKKDRGVLKIVKRVGN-GEET-PMIGDKVYVHYKGKL-SNGKKFDSSHDRNEPFVF 79 E + D GV+K + + G+ GEE P G++V VHY GKL S GK FDSS DRN PF F Sbjct: 4 EKVELTADGGVIKTILKKGDEGEENIPKKGNEVTVHYVGKLESTGKVFDSSFDRNVPFKF 63 Query: 80 SLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELLDFK 138 L +G+VIK WDI V++M+K E C + + Y YG G IP N+ L FEIELL F+ Sbjct: 64 HLEQGEVIKGWDICVSSMRKNEKCLVRIESMYGYGDEGCGESIPGNSVLLFEIELLSFR 122 Score = 52.8 bits (125), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 40/128 (31%), Positives = 71/128 (55%), Gaps = 9/128 (7%) Query: 136 DFKGEDLFEDGGIIRRTKRKG-EGYSN-PNEGATVEIHLEGRC--GGRMFDC---RDVAF 188 +F+ +L DGG+I+ +KG EG N P +G V +H G+ G++FD R+V F Sbjct: 2 EFEKVELTADGGVIKTILKKGDEGEENIPKKGNEVTVHYVGKLESTGKVFDSSFDRNVPF 61 Query: 189 TVGEGEDHDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTLK 248 E ++ G D + M++ E+C++ + YG+G+ G + I N+ L++E+ L Sbjct: 62 KF-HLEQGEVIKGWDICVSSMRKNEKCLVRIESMYGYGDEGCGE-SIPGNSVLLFEIELL 119 Query: 249 SFEKAKES 256 SF + +E+ Sbjct: 120 SFRELEET 127 >3UQI-A nrPDB Length = 108 Score = 103 bits (258), Expect = 1e-22, Method: Composition-based stats. Identities = 50/104 (48%), Positives = 65/104 (62%) Query: 32 GVLKIVKRVGNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVIKAWD 91 GV + G+ P G VHY G L++GK FDSS R +PF F++G+G+VI+ WD Sbjct: 2 GVQVVTLAAGDEATYPKAGQVAVVHYTGTLADGKVFDSSRTRGKPFRFTVGRGEVIRGWD 61 Query: 92 IGVATMKKGEICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELL 135 GVA M G+ L+C P+YAYGS G IP NATL F++ELL Sbjct: 62 EGVAQMSVGQRAKLVCSPDYAYGSRGHPGVIPPNATLTFDVELL 105 Score = 42.7 bits (99), Expect = 3e-04, Method: Composition-based stats. Identities = 33/111 (29%), Positives = 49/111 (44%), Gaps = 10/111 (9%) Query: 147 GIIRRTKRKGEGYSNPNEGATVEIHLEGRCG-GRMFDC-----RDVAFTVGEGEDHDIPI 200 G+ T G+ + P G +H G G++FD + FTVG GE + Sbjct: 2 GVQVVTLAAGDEATYPKAGQVAVVHYTGTLADGKVFDSSRTRGKPFRFTVGRGE---VIR 58 Query: 201 GIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTLKSFE 251 G D+ + +M ++ L P Y +G G P I PNA L ++V L E Sbjct: 59 GWDEGVAQMSVGQRAKLVCSPDYAYGSRGHPGV-IPPNATLTFDVELLRVE 108 >5L1D-B nrPDB Length = 158 Score = 102 bits (255), Expect = 3e-22, Method: Compositional matrix adjust. Identities = 49/97 (50%), Positives = 61/97 (62%) Query: 41 GNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKG 100 G+G P G VHY G L NGKKFDSS DRN+PF F +GK +VIK ++ G A M G Sbjct: 61 GDGRTFPKKGQTCVVHYTGMLQNGKKFDSSRDRNKPFKFRIGKQEVIKGFEEGAAQMSLG 120 Query: 101 EICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELLDF 137 + L C P+ AYG+ G IP NATL F++ELL+ Sbjct: 121 QRAKLTCTPDVAYGATGHPGVIPPNATLIFDVELLNL 157 Score = 38.1 bits (87), Expect = 0.007, Method: Compositional matrix adjust. Identities = 33/111 (29%), Positives = 51/111 (45%), Gaps = 10/111 (9%) Query: 147 GIIRRTKRKGEGYSNPNEGATVEIHLEGRC-GGRMFDC-RD----VAFTVGEGEDHDIPI 200 G+ T G+G + P +G T +H G G+ FD RD F +G+ E + Sbjct: 52 GVEIETISPGDGRTFPKKGQTCVVHYTGMLQNGKKFDSSRDRNKPFKFRIGKQE---VIK 108 Query: 201 GIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTLKSFE 251 G ++ +M ++ L P +G G P I PNA LI++V L + E Sbjct: 109 GFEEGAAQMSLGQRAKLTCTPDVAYGATGHPGV-IPPNATLIFDVELLNLE 158 >5T9S-F nrPDB Length = 108 Score = 102 bits (253), Expect = 4e-22, Method: Compositional matrix adjust. Identities = 49/97 (50%), Positives = 61/97 (62%) Query: 41 GNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKG 100 G+G P G VHY G L NGKKFDSS DRN+PF F +GK +VIK ++ G A M G Sbjct: 11 GDGRTFPKKGQTCVVHYTGMLQNGKKFDSSRDRNKPFKFRIGKQEVIKGFEEGAAQMSLG 70 Query: 101 EICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELLDF 137 + L C P+ AYG+ G IP NATL F++ELL+ Sbjct: 71 QRAKLTCTPDVAYGATGHPGVIPPNATLIFDVELLNL 107 Score = 38.5 bits (88), Expect = 0.007, Method: Compositional matrix adjust. Identities = 33/111 (29%), Positives = 51/111 (45%), Gaps = 10/111 (9%) Query: 147 GIIRRTKRKGEGYSNPNEGATVEIHLEGRC-GGRMFDC-RD----VAFTVGEGEDHDIPI 200 G+ T G+G + P +G T +H G G+ FD RD F +G+ E + Sbjct: 2 GVEIETISPGDGRTFPKKGQTCVVHYTGMLQNGKKFDSSRDRNKPFKFRIGKQE---VIK 58 Query: 201 GIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTLKSFE 251 G ++ +M ++ L P +G G P I PNA LI++V L + E Sbjct: 59 GFEEGAAQMSLGQRAKLTCTPDVAYGATGHPGV-IPPNATLIFDVELLNLE 108 >4GIV-A nrPDB Length = 209 Score = 101 bits (252), Expect = 6e-22, Method: Compositional matrix adjust. Identities = 48/87 (55%), Positives = 57/87 (65%) Query: 50 GDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKP 109 G V VHY G L++G+KF SS DRN+PF F LG G VIK WD GV MK G + L P Sbjct: 122 GQTVSVHYTGWLTDGQKFGSSKDRNDPFAFVLGGGMVIKGWDEGVQGMKVGGVRRLTIPP 181 Query: 110 EYAYGSAGSLPKIPSNATLFFEIELLD 136 + YG+ G+ IP NATL FE+ELLD Sbjct: 182 QLGYGARGAGGVIPPNATLVFEVELLD 208 >2PBC-A nrPDB Length = 102 Score = 100 bits (250), Expect = 1e-21, Method: Compositional matrix adjust. Identities = 48/86 (55%), Positives = 60/86 (69%) Query: 50 GDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKP 109 GD +++HY GKL +G +FDSS +N+PFVFSLG GQVIK WD G+ M +GE L+ Sbjct: 9 GDVLHMHYTGKLEDGTEFDSSLPQNQPFVFSLGTGQVIKGWDQGLLGMCEGEKRKLVIPS 68 Query: 110 EYAYGSAGSLPKIPSNATLFFEIELL 135 E YG G+ PKIP ATL FE+ELL Sbjct: 69 ELGYGERGAPPKIPGGATLVFEVELL 94 >2Y78-A nrPDB Length = 133 Score = 99.8 bits (247), Expect = 2e-21, Method: Composition-based stats. Identities = 52/96 (54%), Positives = 62/96 (64%), Gaps = 1/96 (1%) Query: 41 GNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKG 100 G+G E G V VHY G L++G+KFDSS DRN+PF F LG G VIK WD GV MK G Sbjct: 38 GSGAEA-RAGQTVSVHYTGWLTDGQKFDSSKDRNDPFAFVLGGGMVIKGWDEGVQGMKVG 96 Query: 101 EICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELLD 136 + L P+ YG+ G+ IP NATL FE+ELLD Sbjct: 97 GVRRLTIPPQLGYGARGAGGVIPPNATLVFEVELLD 132 >2ND5-A nrPDB Length = 111 Score = 99.8 bits (247), Expect = 3e-21, Method: Composition-based stats. Identities = 49/98 (50%), Positives = 62/98 (63%) Query: 41 GNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKG 100 G+G P G VHY G L +GKKFDSS DRN+PF F LGK +VI+ W+ GVA M G Sbjct: 14 GDGRTFPKRGQTCVVHYTGMLEDGKKFDSSRDRNKPFKFMLGKQEVIRGWEEGVAQMSVG 73 Query: 101 EICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELLDFK 138 + L P+YAYG+ G IP +ATL F++ELL + Sbjct: 74 QRAKLTISPDYAYGATGHPGIIPPHATLVFDVELLKLE 111 Score = 39.7 bits (91), Expect = 0.003, Method: Composition-based stats. Identities = 30/109 (27%), Positives = 51/109 (46%), Gaps = 6/109 (5%) Query: 147 GIIRRTKRKGEGYSNPNEGATVEIHLEGRC-GGRMFDC---RDVAFTVGEGEDHDIPIGI 202 G+ T G+G + P G T +H G G+ FD R+ F G+ ++ G Sbjct: 5 GVQVETISPGDGRTFPKRGQTCVVHYTGMLEDGKKFDSSRDRNKPFKFMLGK-QEVIRGW 63 Query: 203 DKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTLKSFE 251 ++ + +M ++ L + P Y +G G P I P+A L+++V L E Sbjct: 64 EEGVAQMSVGQRAKLTISPDYAYGATGHPGI-IPPHATLVFDVELLKLE 111 >2L2S-A nrPDB Length = 117 Score = 99.4 bits (246), Expect = 3e-21, Method: Composition-based stats. Identities = 52/96 (54%), Positives = 62/96 (64%), Gaps = 1/96 (1%) Query: 41 GNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKG 100 G+G E G V VHY G L++G+KFDSS DRN+PF F LG G VIK WD GV MK G Sbjct: 22 GSGAEA-RAGQTVSVHYTGWLTDGQKFDSSKDRNDPFAFVLGGGMVIKGWDEGVQGMKVG 80 Query: 101 EICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELLD 136 + L P+ YG+ G+ IP NATL FE+ELLD Sbjct: 81 GVRRLTIPPQLGYGARGAGGVIPPNATLVFEVELLD 116 >4NNR-A nrPDB Length = 142 Score = 98.6 bits (244), Expect = 5e-21, Method: Composition-based stats. Identities = 51/100 (51%), Positives = 65/100 (65%) Query: 36 IVKRVGNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVA 95 + KRV + GD +++HY GKL +G +FDSS +N+PFVFSLG GQVIK WD G+ Sbjct: 35 VKKRVDHCPIKSRKGDVLHMHYTGKLEDGTEFDSSLPQNQPFVFSLGTGQVIKGWDQGLL 94 Query: 96 TMKKGEICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELL 135 M +GE L+ E YG G+ PKIP ATL FE+ELL Sbjct: 95 GMCEGEKRKLVIPSELGYGERGAPPKIPGGATLVFEVELL 134 >2LGO-A nrPDB Length = 130 Score = 98.6 bits (244), Expect = 5e-21, Method: Composition-based stats. Identities = 50/95 (52%), Positives = 59/95 (62%) Query: 41 GNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKG 100 G+G P G KV VHY G+ +GK+FDSS R +PF F+LG G+VIK WD GVATM G Sbjct: 34 GDGVTKPQAGKKVTVHYDGRFPDGKQFDSSRSRGKPFQFTLGAGEVIKGWDQGVATMTLG 93 Query: 101 EICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELL 135 E + AYG G P IP ATL FE+ELL Sbjct: 94 EKALFTIPYQLAYGERGYPPVIPPKATLVFEVELL 128 Score = 44.7 bits (104), Expect = 9e-05, Method: Composition-based stats. Identities = 31/98 (31%), Positives = 48/98 (48%), Gaps = 10/98 (10%) Query: 156 GEGYSNPNEGATVEIHLEGRC-GGRMFDC-----RDVAFTVGEGEDHDIPIGIDKALEKM 209 G+G + P G V +H +GR G+ FD + FT+G GE + G D+ + M Sbjct: 34 GDGVTKPQAGKKVTVHYDGRFPDGKQFDSSRSRGKPFQFTLGAGE---VIKGWDQGVATM 90 Query: 210 QREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTL 247 E+ + + + +GE G P I P A L++EV L Sbjct: 91 TLGEKALFTIPYQLAYGERGYPPV-IPPKATLVFEVEL 127 >1YAT-A nrPDB Length = 113 Score = 97.8 bits (242), Expect = 9e-21, Method: Composition-based stats. Identities = 47/95 (49%), Positives = 58/95 (61%) Query: 41 GNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKG 100 G+G P GD V +HY G L NG+KFDSS DR PF ++G GQVIK WD+G+ + G Sbjct: 16 GDGATFPKTGDLVTIHYTGTLENGQKFDSSVDRGSPFQCNIGVGQVIKGWDVGIPKLSVG 75 Query: 101 EICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELL 135 E L YAYG G IP N+TL F++ELL Sbjct: 76 EKARLTIPGPYAYGPRGFPGLIPPNSTLVFDVELL 110 >5HUA-A nrPDB Length = 115 Score = 96.3 bits (238), Expect = 3e-20, Method: Composition-based stats. Identities = 48/95 (50%), Positives = 58/95 (61%) Query: 41 GNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKG 100 G+G+ P GD V +HY G L NG+KFDSS DR PF ++G GQVIK WD G+ + G Sbjct: 18 GDGKTFPKQGDLVTIHYTGTLENGQKFDSSVDRGSPFQCNIGVGQVIKGWDAGIPKLSVG 77 Query: 101 EICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELL 135 E L YAYG G IP NATL F++ELL Sbjct: 78 EKARLTIPGPYAYGPRGFPGLIPPNATLIFDVELL 112 Score = 38.5 bits (88), Expect = 0.007, Method: Composition-based stats. Identities = 34/107 (31%), Positives = 47/107 (43%), Gaps = 6/107 (5%) Query: 145 DGGIIRRTKRKGEGYSNPNEGATVEIHLEGRC-GGRMFDC---RDVAFTVGEGEDHDIPI 200 +GG+ G+G + P +G V IH G G+ FD R F G I Sbjct: 7 EGGVKIDRLSPGDGKTFPKQGDLVTIHYTGTLENGQKFDSSVDRGSPFQCNIGVGQVIK- 65 Query: 201 GIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTL 247 G D + K+ E+ L + Y +G G P I PNA LI++V L Sbjct: 66 GWDAGIPKLSVGEKARLTIPGPYAYGPRGFPGL-IPPNATLIFDVEL 111 >2IF4-A nrPDB Length = 338 Score = 88.6 bits (218), Expect = 5e-18, Method: Compositional matrix adjust. Identities = 59/220 (26%), Positives = 114/220 (51%), Gaps = 6/220 (2%) Query: 201 GIDKALEKMQREEQCILYLGPRYGFGEAGKPKF-GIEPNAELIYEVTLKSFEKAKE---S 256 G+ + M+ E+ ++++G +G+ G F + P A+L+YEV + F++ KE Sbjct: 108 GLAIGVASMKSGERALVHVGWELAYGKEGNFSFPNVPPMADLLYEVEVIGFDETKEGKAR 167 Query: 257 WEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWL--EMEYGLSEKESKASES 314 +M +E++ A K G FK K +A+ QY ++++ + + L K + + Sbjct: 168 SDMTVEERIGAADRRKMDGNSLFKEEKLEEAMQQYEMAIAYMGDDFMFQLYGKYQDMALA 227 Query: 315 FLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDF 374 LN+A C +KL+ Y +A+ C+ L + N K L+RRG+A+ + + +SA+ DF Sbjct: 228 VKNPCHLNIAACLIKLKRYDEAIGHCNIVLTEEEKNPKALFRRGKAKAELGQMDSARDDF 287 Query: 375 EKVLEVNPQNKAARLQISMCQKKAKEHNERDRRIYANMFK 414 K + P +KA R ++ ++ K ++ + +Y +FK Sbjct: 288 RKAQKYAPDDKAIRRELRALAEQEKALYQKQKEMYKGIFK 327 Score = 53.1 bits (126), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 36/112 (32%), Positives = 56/112 (50%), Gaps = 5/112 (4%) Query: 30 DRGVLKIVKRVGNGEETPMIGDKVYVHYKGKLSNGK-KFDSSHDRNEPFVFSLGK-GQVI 87 D V K + + G+G + P ++HY+ N + KF+ + +P LGK + + Sbjct: 48 DEKVSKQIIKEGHGSK-PSKYSTCFLHYRAWTKNSQHKFEDTWHEQQPIELVLGKEKKEL 106 Query: 88 KAWDIGVATMKKGEICHLLCKPEYAYGSAG--SLPKIPSNATLFFEIELLDF 137 IGVA+MK GE + E AYG G S P +P A L +E+E++ F Sbjct: 107 AGLAIGVASMKSGERALVHVGWELAYGKEGNFSFPNVPPMADLLYEVEVIGF 158 >5I7P-A nrPDB Length = 161 Score = 84.0 bits (206), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 39/74 (52%), Positives = 47/74 (63%) Query: 41 GNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKG 100 G+G P G VHY G L +GKKFDSS DRN+PF F LGK +VI+ W+ GVA M G Sbjct: 10 GDGRTFPKRGQTAVVHYTGMLEDGKKFDSSRDRNKPFKFMLGKQEVIRGWEEGVAQMSVG 69 Query: 101 EICHLLCKPEYAYG 114 + L P+YAYG Sbjct: 70 QRAKLTISPDYAYG 83 >5I7Q-A nrPDB Length = 162 Score = 83.6 bits (205), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 39/74 (52%), Positives = 47/74 (63%) Query: 41 GNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKG 100 G+G P G VHY G L +GKKFDSS DRN+PF F LGK +VI+ W+ GVA M G Sbjct: 10 GDGRTFPKRGQTAVVHYTGMLEDGKKFDSSRDRNKPFKFMLGKQEVIRGWEEGVAQMSVG 69 Query: 101 EICHLLCKPEYAYG 114 + L P+YAYG Sbjct: 70 QRAKLTISPDYAYG 83 >1IHG-A nrPDB Length = 370 Score = 83.6 bits (205), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 42/144 (29%), Positives = 79/144 (54%), Gaps = 1/144 (0%) Query: 271 VKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYGLSEKESKAS-ESFLLAAFLNLAMCYLK 329 +K G +FK + A+ +Y K++ ++E +E A + L+ LN+ C LK Sbjct: 226 LKNIGNTFFKSQNWEMAIKKYTKVLRYVEGSRAAAEDADGAKLQPVALSCVLNIGACKLK 285 Query: 330 LREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEVNPQNKAARL 389 + ++ AV+ C +AL +D +N K LYRR + + E++ A D +K E+ P++KA + Sbjct: 286 MSDWQGAVDSCLEALEIDPSNTKALYRRAQGWQGLKEYDQALADLKKAQEIAPEDKAIQA 345 Query: 390 QISMCQKKAKEHNERDRRIYANMF 413 ++ ++K K ++++ YA MF Sbjct: 346 ELLKVKQKIKAQKDKEKAAYAKMF 369 >3B7X-A nrPDB Length = 134 Score = 83.6 bits (205), Expect = 2e-16, Method: Composition-based stats. Identities = 47/109 (43%), Positives = 64/109 (58%), Gaps = 2/109 (1%) Query: 30 DRGVLKIVKRVGNGEETPMIGDKVYVHYKGKLSN-GKKFDSSHDRNEPFVFSLGKGQVIK 88 DRGVLK V R G G+ V V Y G L + + FDS++ R P + LG+ + Sbjct: 25 DRGVLKDVIREGAGDLVAPDA-SVLVKYSGYLEHMDRPFDSNYFRKTPRLMKLGEDITLW 83 Query: 89 AWDIGVATMKKGEICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELLDF 137 ++G+ +M++GE+ L KP YAYG+ G P IP N T+ FEIELLDF Sbjct: 84 GMELGLLSMRRGELARFLFKPNYAYGTLGCPPLIPPNTTVLFEIELLDF 132 Score = 33.5 bits (75), Expect = 0.20, Method: Composition-based stats. Identities = 31/114 (27%), Positives = 48/114 (42%), Gaps = 6/114 (5%) Query: 141 DLFEDGGIIRRTKRKGEG-YSNPNEGATVEIHLEGRCGGRMFDC---RDVAFTVGEGEDH 196 D+ D G+++ R+G G P+ V+ R FD R + GED Sbjct: 21 DISGDRGVLKDVIREGAGDLVAPDASVLVKYSGYLEHMDRPFDSNYFRKTPRLMKLGEDI 80 Query: 197 DIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTLKSF 250 + G++ L M+R E P Y +G G P I PN +++E+ L F Sbjct: 81 TL-WGMELGLLSMRRGELARFLFKPNYAYGTLGCPPL-IPPNTTVLFEIELLDF 132 >1Q6H-A nrPDB Length = 224 Score = 83.2 bits (204), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 50/107 (46%), Positives = 64/107 (59%), Gaps = 4/107 (3%) Query: 32 GVLKIVKRVGNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVIKAWD 91 G++ V G GE P D V V+YKG L +GK+FD+S+ R EP F L VI W Sbjct: 122 GLVYQVVEAGKGE-APKDSDTVVVNYKGTLIDGKEFDNSYTRGEPLSFRLDG--VIPGWT 178 Query: 92 IGVATMKKGEICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELLDFK 138 G+ +KKG L+ PE AYG AG +P IP N+TL F++ELLD K Sbjct: 179 EGLKNIKKGGKIKLVIPPELAYGKAG-VPGIPPNSTLVFDVELLDVK 224 >4BF8-A nrPDB Length = 117 Score = 82.8 bits (203), Expect = 3e-16, Method: Compositional matrix adjust. Identities = 42/89 (47%), Positives = 58/89 (65%), Gaps = 2/89 (2%) Query: 50 GDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKP 109 G +V + Y GKL NGK FD + + +PFVF LG+G+VIK WDIGVA M G ++ Sbjct: 31 GTRVGMRYVGKLKNGKVFDK-NTKGKPFVFKLGQGEVIKGWDIGVAGMAVGGERRIVIPA 89 Query: 110 EYAYGSAGSLPKIPSNATLFFEIELLDFK 138 YAYG +LP IP+N+ L F+++L+ K Sbjct: 90 PYAYGKQ-ALPGIPANSELTFDVKLVSMK 117 >5HW8-A nrPDB Length = 122 Score = 80.5 bits (197), Expect = 1e-15, Method: Composition-based stats. Identities = 51/141 (36%), Positives = 66/141 (46%), Gaps = 30/141 (21%) Query: 11 EESPTATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGKLSNGKKFDSS 70 EE P + ++G++ T K GD V +HY GKL+NGK+FDSS Sbjct: 1 EELPQIEIVQEGDNTTFAKP-------------------GDTVTIHYDGKLTNGKEFDSS 41 Query: 71 HDRNEPFVFSLGKGQVIKAWDIGVAT-----------MKKGEICHLLCKPEYAYGSAGSL 119 R +PF ++G GQVIK WDI + + KG L P AYG G Sbjct: 42 RKRGKPFTCTVGVGQVIKGWDISLTNNYGKGGANLPKISKGTKAILTIPPNLAYGPRGIP 101 Query: 120 PKIPSNATLFFEIELLDFKGE 140 I N TL FE+ELL G+ Sbjct: 102 GIIGPNETLVFEVELLGVNGQ 122 >2MPH-A nrPDB Length = 224 Score = 79.3 bits (194), Expect = 3e-15, Method: Compositional matrix adjust. Identities = 52/141 (36%), Positives = 72/141 (51%), Gaps = 11/141 (7%) Query: 5 EGAKNNEESPTATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGKLSNG 64 + K NE+ P T +E+ D K K V + G+ P GD V+ Y G L +G Sbjct: 86 KNVKLNEDKPKETKSEETLDEGPPK---YTKSVLKKGDKTNFPKKGDVVHCWYTGTLQDG 142 Query: 65 KKFDSSHDRN-------EPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAG 117 FD++ + +P F +G G+VI+ WD + TM KGE L +PE+AYG G Sbjct: 143 TVFDTNIQTSAKKKKNAKPLSFKVGVGKVIRGWDEALLTMSKGEKARLEIEPEWAYGKKG 202 Query: 118 SL-PKIPSNATLFFEIELLDF 137 KIP NA L FE+EL+D Sbjct: 203 QPDAKIPPNAKLTFEVELVDI 223 Score = 47.0 bits (110), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 32/107 (29%), Positives = 52/107 (48%), Gaps = 16/107 (14%) Query: 154 RKGEGYSNPNEGATVEIHLEGRC-GGRMFD------------CRDVAFTVGEGEDHDIPI 200 +KG+ + P +G V G G +FD + ++F VG G+ + Sbjct: 117 KKGDKTNFPKKGDVVHCWYTGTLQDGTVFDTNIQTSAKKKKNAKPLSFKVGVGK---VIR 173 Query: 201 GIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTL 247 G D+AL M + E+ L + P + +G+ G+P I PNA+L +EV L Sbjct: 174 GWDEALLTMSKGEKARLEIEPEWAYGKKGQPDAKIPPNAKLTFEVEL 220 >5MGX-E nrPDB Length = 290 Score = 77.8 bits (190), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 68/287 (23%), Positives = 123/287 (42%), Gaps = 9/287 (3%) Query: 141 DLFEDGGIIRRTKRKGE-GYSNPNEGATVEIHLEGRC--GGRMFDCRDVAFTVGEGEDHD 197 D+ +G + ++T G G S P +G V +HL+ G R+ + ++ FT+G D D Sbjct: 5 DILGNGLLRKKTLVPGPPGSSRPVKGQVVTVHLQTSLENGTRVQEEPELVFTLG---DCD 61 Query: 198 IPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTLKSFEKAKESW 257 + +D ++ M E ++ +Y +G G+ + I P+A L EVTLK+ + Sbjct: 62 VIQALDLSVPLMDVGETAMVTADSKYCYGPQGRSPY-IPPHAALCLEVTLKTAVDGPDLE 120 Query: 258 EMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWL--EMEYGLSEKESKASESF 315 + +E++ A +E G +++ ++ A Y + + + ++ +E Sbjct: 121 MLTGQERVALANRKRECGNAHYQRADFVLAANSYDLAIKAITSSAKVDMTFEEEAQLLQL 180 Query: 316 LLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFE 375 + NLA LKL Y A+ C L N K L+R+G+ E+ A Sbjct: 181 KVKCLNNLAASQLKLDHYRAALRSCSLVLEHQPDNIKALFRKGKVLAQQGEYSEAIPILR 240 Query: 376 KVLEVNPQNKAARLQISMCQKKAKEHNERDRRIYANMFKKFAEQDAK 422 L++ P NK ++S KK + +Y M + AK Sbjct: 241 AALKLEPSNKTIHAELSKLVKKHAAQRSTETALYRKMLGNPSRLPAK 287 Score = 60.1 bits (144), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 37/102 (36%), Positives = 48/102 (47%), Gaps = 7/102 (6%) Query: 43 GEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEP-FVFSLGKGQVIKAWDIGVATMKKGE 101 G P+ G V VH + L NG + + EP VF+LG VI+A D+ V M GE Sbjct: 23 GSSRPVKGQVVTVHLQTSLENGTRV-----QEEPELVFTLGDCDVIQALDLSVPLMDVGE 77 Query: 102 ICHLLCKPEYAYGSAGSLPKIPSNATLFFEIEL-LDFKGEDL 142 + +Y YG G P IP +A L E+ L G DL Sbjct: 78 TAMVTADSKYCYGPQGRSPYIPPHAALCLEVTLKTAVDGPDL 119 >5D75-A nrPDB Length = 124 Score = 75.9 bits (185), Expect = 4e-14, Method: Compositional matrix adjust. Identities = 44/111 (39%), Positives = 60/111 (54%), Gaps = 8/111 (7%) Query: 35 KIVKRVGNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRN-------EPFVFSLGKGQVI 87 K V + G+ P GD V+ Y G L +G FD++ + +P F +G G+VI Sbjct: 5 KSVLKKGDKTNFPKKGDVVHCWYTGTLQDGTVFDTNIQTSAKKKKNAKPLSFKVGVGKVI 64 Query: 88 KAWDIGVATMKKGEICHLLCKPEYAYGSAGSL-PKIPSNATLFFEIELLDF 137 + WD + TM KGE L +PE+AYG G KIP NA L FE+EL+D Sbjct: 65 RGWDEALLTMSKGEKARLEIEPEWAYGKKGQPDAKIPPNAKLTFEVELVDI 115 Score = 45.8 bits (107), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 32/107 (29%), Positives = 52/107 (48%), Gaps = 16/107 (14%) Query: 154 RKGEGYSNPNEGATVEIHLEGRC-GGRMFD------------CRDVAFTVGEGEDHDIPI 200 +KG+ + P +G V G G +FD + ++F VG G+ + Sbjct: 9 KKGDKTNFPKKGDVVHCWYTGTLQDGTVFDTNIQTSAKKKKNAKPLSFKVGVGK---VIR 65 Query: 201 GIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTL 247 G D+AL M + E+ L + P + +G+ G+P I PNA+L +EV L Sbjct: 66 GWDEALLTMSKGEKARLEIEPEWAYGKKGQPDAKIPPNAKLTFEVEL 112 >5B8I-C nrPDB Length = 130 Score = 75.1 bits (183), Expect = 6e-14, Method: Compositional matrix adjust. Identities = 46/115 (40%), Positives = 64/115 (55%), Gaps = 10/115 (8%) Query: 29 KDRGVLKIVKRVGNGEETPMIGDKVYVHYKGKLSN---------GKKFDSSHDRNEPFVF 79 K GV K + + GNG + P+ GD + ++Y+G L + G+KFDS+ +R E F Sbjct: 9 KGSGVTKKILKEGNGVDKPVKGDDIVMNYRGCLYDSSKPSEHFMGRKFDSTEERGE-FKT 67 Query: 80 SLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLPKIPSNATLFFEIEL 134 +G G VI+ WD V M GE L +YAYG+ G IP +ATL FE+EL Sbjct: 68 KIGIGVVIRGWDEAVLQMSLGEKSILTITDDYAYGARGFPGLIPPHATLVFEVEL 122 Score = 36.6 bits (83), Expect = 0.021, Method: Compositional matrix adjust. Identities = 34/121 (28%), Positives = 55/121 (45%), Gaps = 19/121 (15%) Query: 143 FEDG-GIIRRTKRKGEGYSNPNEGATVEIHLEG----------RCGGRMFDCRD----VA 187 FE G G+ ++ ++G G P +G + ++ G GR FD + Sbjct: 7 FEKGSGVTKKILKEGNGVDKPVKGDDIVMNYRGCLYDSSKPSEHFMGRKFDSTEERGEFK 66 Query: 188 FTVGEGEDHDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTL 247 +G G + G D+A+ +M E+ IL + Y +G G P I P+A L++EV L Sbjct: 67 TKIGIGV---VIRGWDEAVLQMSLGEKSILTITDDYAYGARGFPGL-IPPHATLVFEVEL 122 Query: 248 K 248 K Sbjct: 123 K 123 >1JVW-A nrPDB Length = 167 Score = 72.8 bits (177), Expect = 3e-13, Method: Compositional matrix adjust. Identities = 37/98 (37%), Positives = 53/98 (54%), Gaps = 2/98 (2%) Query: 41 GNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKG 100 G+G+ P I DK VHY G+L +G FDSS +R +P F +VIK W + M++G Sbjct: 47 GSGKRAPAIDDKCEVHYTGRLRDGTVFDSSRERGKPTTFR--PNEVIKGWTEALQLMREG 104 Query: 101 EICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELLDFK 138 + L + AYG G IP + L F++EL+ K Sbjct: 105 DRWRLFIPYDLAYGVTGGGGMIPPYSPLEFDVELISIK 142 >1Y0O-A nrPDB Length = 129 Score = 69.7 bits (169), Expect = 2e-12, Method: Composition-based stats. Identities = 45/109 (41%), Positives = 57/109 (52%), Gaps = 12/109 (11%) Query: 38 KRVGNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDI----- 92 K VG G E + G + HY GKL NGK FDSS++R +P F +G G+VIK WD Sbjct: 19 KVVGYGPEA-VKGQLIKAHYVGKLENGKVFDSSYNRGKPLTFRIGVGEVIKGWDQGILGS 77 Query: 93 -GVATMKKGEICHLLCKPEYAYGSAGSLPK-----IPSNATLFFEIELL 135 G+ M G L PE AYG G+ K IP + L F+IE + Sbjct: 78 DGIPPMLTGGKRTLRIPPELAYGDRGAGCKGGSCLIPPASVLLFDIEYI 126 >6FO1-G nrPDB Length = 665 Score = 67.8 bits (164), Expect = 1e-11, Method: Compositional matrix adjust. Identities = 50/153 (32%), Positives = 83/153 (54%), Gaps = 17/153 (11%) Query: 244 EVTLKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYG 303 ++ +KS E E +++ ++ +QA K++G +FK GKY +A+ Y + G Sbjct: 260 DIVIKSTEG--ERKQIEAQQNKQQAISEKDRGNGFFKEGKYERAIECYTR---------G 308 Query: 304 LSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLL 363 ++ + A LL A N AM YLK+++Y +A + C +A+ LD + K RRG A+ Sbjct: 309 IAADGANA----LLPA--NRAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTARTF 362 Query: 364 MNEFESAKGDFEKVLEVNPQNKAARLQISMCQK 396 + + AK DFE VL + P NK A ++S +K Sbjct: 363 LGKLNEAKQDFETVLLLEPGNKQAVTELSKIKK 395 Score = 63.5 bits (153), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 38/119 (31%), Positives = 62/119 (52%), Gaps = 15/119 (12%) Query: 266 EQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYGLSEKESKASESFLLAAFLNLAM 325 ++A ++KEKG YFK GKY +A+ Y K G+ ++ + N A Sbjct: 131 QKALVLKEKGNKYFKQGKYDEAIDCYTK---------GMD------ADPYNPVLPTNRAS 175 Query: 326 CYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEVNPQN 384 Y +L+++ A C+ A+ L+ + K RRG A+ + + E AK D+E+VLE+ P N Sbjct: 176 AYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNN 234 >4MSP-A nrPDB Length = 200 Score = 63.2 bits (152), Expect = 3e-10, Method: Compositional matrix adjust. Identities = 37/92 (40%), Positives = 51/92 (55%), Gaps = 4/92 (4%) Query: 50 GDKVYVHYKGKL-SNGKKFDSSHDRN--EPFVFSLGKGQVIKAWDIGVATMKKGEICHLL 106 GD + VHY+G L +G F S+H N +P F+LG + +K WD G+ M GE L+ Sbjct: 34 GDLMLVHYEGYLEKDGSLFHSTHKHNNGQPIWFTLGILEALKGWDQGLKGMCVGEKRKLI 93 Query: 107 CKPEYAYGSAGSLPKIPSNATLFFEIELLDFK 138 P YG G KIP +TL F I+LL+ + Sbjct: 94 IPPALGYGKEGK-GKIPPESTLIFNIDLLEIR 124 >4DIP-A nrPDB Length = 125 Score = 62.4 bits (150), Expect = 4e-10, Method: Compositional matrix adjust. Identities = 37/92 (40%), Positives = 51/92 (55%), Gaps = 4/92 (4%) Query: 50 GDKVYVHYKGKL-SNGKKFDSSHDRN--EPFVFSLGKGQVIKAWDIGVATMKKGEICHLL 106 GD + VHY+G L +G F S+H N +P F+LG + +K WD G+ M GE L+ Sbjct: 32 GDLMLVHYEGYLEKDGSLFHSTHKHNNGQPIWFTLGILEALKGWDQGLKGMCVGEKRKLI 91 Query: 107 CKPEYAYGSAGSLPKIPSNATLFFEIELLDFK 138 P YG G KIP +TL F I+LL+ + Sbjct: 92 IPPALGYGKEGK-GKIPPESTLIFNIDLLEIR 122 >5JJT-A nrPDB Length = 479 Score = 59.3 bits (142), Expect = 4e-09, Method: Compositional matrix adjust. Identities = 39/118 (33%), Positives = 59/118 (50%), Gaps = 15/118 (12%) Query: 279 FKGGKYMQAVIQYGKIVSWLEMEYGLSEKESKASESFLLAAFLNLAMCYLKLREYTKAVE 338 FKG KY A+ Y K + E ++ + A N A + KL EY A++ Sbjct: 20 FKGHKYSSAIDLYTKAI------------ELNSNNAVYWA---NRAFAHTKLEEYGSAIQ 64 Query: 339 CCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEVNPQNKAARLQISMCQK 396 KA+ +DS KG YRRG A L M +F+ A DF++V ++P + A ++ C+K Sbjct: 65 DASKAIEVDSRYSKGYYRRGAAYLAMGKFKDALKDFQQVKRLSPNDPDATRKLKECEK 122 >3EY6-A nrPDB Length = 121 Score = 57.4 bits (137), Expect = 1e-08, Method: Composition-based stats. Identities = 34/93 (36%), Positives = 45/93 (48%), Gaps = 6/93 (6%) Query: 43 GEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEP-FVFSLGKGQVIKAWDIGVATMKKGE 101 G P+ G V VH + L NG + + EP VF+LG VI+A D+ V M GE Sbjct: 24 GSSRPVKGQVVTVHLQTSLENGTRV-----QEEPELVFTLGDCDVIQALDLSVPLMDVGE 78 Query: 102 ICHLLCKPEYAYGSAGSLPKIPSNATLFFEIEL 134 + +Y YG G P IP +A L E+ L Sbjct: 79 TAMVTADSKYCYGPQGRSPYIPPHAALCLEVTL 111 >2MF9-A nrPDB Length = 157 Score = 56.2 bits (134), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 35/94 (37%), Positives = 46/94 (48%), Gaps = 7/94 (7%) Query: 43 GEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEP-FVFSLGKGQVIKAWDIGVATMKKGE 101 G P+ G V VH + L NG + + EP VF+LG VI+A D+ V M GE Sbjct: 56 GSSRPVKGQVVTVHLQTSLENGTRV-----QEEPELVFTLGDCDVIQALDLSVPLMDVGE 110 Query: 102 ICHLLCKPEYAYGSAGSL-PKIPSNATLFFEIEL 134 + +Y YG GS P IP +A L E+ L Sbjct: 111 TAMVTADSKYCYGPQGSRSPYIPPHAALCLEVTL 144 Score = 45.1 bits (105), Expect = 7e-05, Method: Compositional matrix adjust. Identities = 33/112 (29%), Positives = 56/112 (50%), Gaps = 6/112 (5%) Query: 141 DLFEDGGIIRRTKRKGE-GYSNPNEGATVEIHLEGRC--GGRMFDCRDVAFTVGEGEDHD 197 D+ +G + ++T G G S P +G V +HL+ G R+ + ++ FT+G D D Sbjct: 38 DILGNGLLRKKTLVPGPPGSSRPVKGQVVTVHLQTSLENGTRVQEEPELVFTLG---DCD 94 Query: 198 IPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTLKS 249 + +D ++ M E ++ +Y +G G I P+A L EVTLK+ Sbjct: 95 VIQALDLSVPLMDVGETAMVTADSKYCYGPQGSRSPYIPPHAALCLEVTLKT 146 >5JHE-A nrPDB Length = 397 Score = 55.8 bits (133), Expect = 4e-08, Method: Compositional matrix adjust. Identities = 39/156 (25%), Positives = 70/156 (44%), Gaps = 7/156 (4%) Query: 265 LEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYGLSEKESKASESFL---LAAFL 321 LE A I+KE GT+ FK Y A +Y K ++++ + + + + F+ + +L Sbjct: 241 LEAANIIKESGTLLFKKKDYSNAFFKYRKSLNYINEYMPEPDVDKERNIQFINLKMKIYL 300 Query: 322 NLAMCYLKLREYTKAVECCDKALGLDSA----NEKGLYRRGEAQLLMNEFESAKGDFEKV 377 NL++ L Y A+ L +D+ K YRRG + L + A D+ Sbjct: 301 NLSLVLFNLERYDDAIMYATYLLEMDNVPNRDQAKAYYRRGNSYLKKKRLDEALQDYIFC 360 Query: 378 LEVNPQNKAARLQISMCQKKAKEHNERDRRIYANMF 413 E NP ++ +I + +E+ E+ R+ + F Sbjct: 361 KEKNPDDEVIEQRIEYVNRLIEENKEKTRKNISKFF 396 >2D9F-A nrPDB Length = 135 Score = 53.9 bits (128), Expect = 1e-07, Method: Composition-based stats. Identities = 35/94 (37%), Positives = 46/94 (48%), Gaps = 7/94 (7%) Query: 43 GEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEP-FVFSLGKGQVIKAWDIGVATMKKGE 101 G P+ G V VH + L NG + + EP VF+LG VI+A D+ V M GE Sbjct: 30 GSSRPVKGQVVTVHLQTSLENGTRV-----QEEPELVFTLGDCDVIQALDLSVPLMDVGE 84 Query: 102 ICHLLCKPEYAYGSAGSL-PKIPSNATLFFEIEL 134 + +Y YG GS P IP +A L E+ L Sbjct: 85 TAMVTADSKYCYGPQGSRSPYIPPHAALCLEVTL 118 Score = 42.0 bits (97), Expect = 6e-04, Method: Composition-based stats. Identities = 33/112 (29%), Positives = 56/112 (50%), Gaps = 6/112 (5%) Query: 141 DLFEDGGIIRRTKRKGE-GYSNPNEGATVEIHLEGRC--GGRMFDCRDVAFTVGEGEDHD 197 D+ +G + ++T G G S P +G V +HL+ G R+ + ++ FT+G D D Sbjct: 12 DILGNGLLRKKTLVPGPPGSSRPVKGQVVTVHLQTSLENGTRVQEEPELVFTLG---DCD 68 Query: 198 IPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTLKS 249 + +D ++ M E ++ +Y +G G I P+A L EVTLK+ Sbjct: 69 VIQALDLSVPLMDVGETAMVTADSKYCYGPQGSRSPYIPPHAALCLEVTLKT 120 >2F4E-A nrPDB Length = 180 Score = 52.4 bits (124), Expect = 5e-07, Method: Compositional matrix adjust. Identities = 36/112 (32%), Positives = 56/112 (50%), Gaps = 5/112 (4%) Query: 30 DRGVLKIVKRVGNGEETPMIGDKVYVHYKGKLSNGK-KFDSSHDRNEPFVFSLGK-GQVI 87 D V K + + G+G + P ++HY+ N + KF+ + +P LGK + + Sbjct: 48 DEKVSKQIIKEGHGSK-PSKYSTCFLHYRAWTKNSQHKFEDTWHEQQPIELVLGKEKKEL 106 Query: 88 KAWDIGVATMKKGEICHLLCKPEYAYGSAG--SLPKIPSNATLFFEIELLDF 137 IGVA+MK GE + E AYG G S P +P A L +E+E++ F Sbjct: 107 AGLAIGVASMKSGERALVHVGWELAYGKEGNFSFPNVPPMADLLYEVEVIGF 158 >1A17-A nrPDB Length = 166 Score = 52.0 bits (123), Expect = 5e-07, Method: Compositional matrix adjust. Identities = 36/136 (26%), Positives = 64/136 (47%), Gaps = 15/136 (11%) Query: 265 LEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYGLSEKESKASESFLLAAFLNLA 324 L++A +K + YFK Y A+ Y + + E S + + N + Sbjct: 10 LKRAEELKTQANDYFKAKDYENAIKFYSQAI------------ELNPSNAIY---YGNRS 54 Query: 325 MCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEVNPQN 384 + YL+ Y A+ +A+ LD KG YRR + + + +F +A D+E V++V P + Sbjct: 55 LAYLRTECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPHD 114 Query: 385 KAARLQISMCQKKAKE 400 K A+++ C K K+ Sbjct: 115 KDAKMKYQECNKIVKQ 130 >4JA9-A nrPDB Length = 488 Score = 51.6 bits (122), Expect = 6e-07, Method: Compositional matrix adjust. Identities = 36/136 (26%), Positives = 63/136 (46%), Gaps = 15/136 (11%) Query: 265 LEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYGLSEKESKASESFLLAAFLNLA 324 L++A +K + YFK Y A+ Y + + E S + N + Sbjct: 14 LKRAEELKTQANDYFKAKDYENAIKFYSQAI------------ELNPSNAIYYG---NRS 58 Query: 325 MCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEVNPQN 384 + YL+ Y A+ +A+ LD KG YRR + + + +F +A D+E V++V P + Sbjct: 59 LAYLRTECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPND 118 Query: 385 KAARLQISMCQKKAKE 400 K A+++ C K K+ Sbjct: 119 KDAKMKYQECSKIVKQ 134 >1FD9-A nrPDB Length = 213 Score = 51.6 bits (122), Expect = 8e-07, Method: Compositional matrix adjust. Identities = 34/102 (33%), Positives = 44/102 (43%), Gaps = 3/102 (2%) Query: 37 VKRVGNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVAT 96 V GNG + P D V V Y G+L +G FDS+ +P F + QVI W + Sbjct: 112 VINSGNGVK-PGKSDTVTVEYTGRLIDGTVFDSTEKTGKPATFQV--SQVIPGWTEALQL 168 Query: 97 MKKGEICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELLDFK 138 M G + AYG I N TL F+I L+ K Sbjct: 169 MPAGSTWEIYVPSGLAYGPRSVGGPIGPNETLIFKIHLISVK 210 >2C2L-A nrPDB Length = 281 Score = 49.3 bits (116), Expect = 4e-06, Method: Compositional matrix adjust. Identities = 28/110 (25%), Positives = 52/110 (47%), Gaps = 15/110 (13%) Query: 271 VKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYGLSEKESKASESFLLAAFLNLAMCYLKL 330 +KE+G F G KY +A YG+ ++ + + N A+CYLK+ Sbjct: 7 LKEQGNRLFVGRKYPEAAACYGRAIT---------------RNPLVAVYYTNRALCYLKM 51 Query: 331 REYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEV 380 ++ +A+ C +AL LD + K + G+ QL M ++ A + ++ + Sbjct: 52 QQPEQALADCRRALELDGQSVKAHFFLGQCQLEMESYDEAIANLQRAYSL 101 >6H3J-B nrPDB Length = 176 Score = 48.5 bits (114), Expect = 6e-06, Method: Compositional matrix adjust. Identities = 31/89 (34%), Positives = 41/89 (46%), Gaps = 6/89 (6%) Query: 47 PMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLL 106 P + + V YKG +NGK FD S E +SL +I W G+ +K G L Sbjct: 91 PTLNSNITVIYKGYFTNGKVFDES---TEGVSYSL--RTLIPGWKEGIPLLKSGGEIQLF 145 Query: 107 CKPEYAYGSAGSLPKIPSNATLFFEIELL 135 YGS G+ +P A L FEI L+ Sbjct: 146 VPAHLGYGSNGN-KTVPGGAVLIFEITLV 173 >2VCD-A nrPDB Length = 137 Score = 47.4 bits (111), Expect = 1e-05, Method: Composition-based stats. Identities = 33/98 (33%), Positives = 43/98 (43%), Gaps = 3/98 (3%) Query: 41 GNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKG 100 GNG + P D V V Y G+L +G FDS+ +P F + QVI W + M G Sbjct: 40 GNGVK-PGKSDTVTVEYTGRLIDGTVFDSTEKTGKPATFQV--SQVIPGWTEALQLMPAG 96 Query: 101 EICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELLDFK 138 + AYG I N TL F+I L+ K Sbjct: 97 STWEIYVPSGLAYGPRSVGGPIGPNETLIFKIHLISVK 134 >2GW1-A nrPDB Length = 514 Score = 45.4 bits (106), Expect = 6e-05, Method: Compositional matrix adjust. Identities = 27/91 (29%), Positives = 47/91 (51%), Gaps = 1/91 (1%) Query: 303 GLSEKESKASESF-LLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQ 361 G E KA E F + +++ +A+ + T+ DKAL LDS N Y RG+ Sbjct: 255 GAHEDIKKAIELFPRVNSYIYMALIMADRNDSTEYYNYFDKALKLDSNNSSVYYHRGQMN 314 Query: 362 LLMNEFESAKGDFEKVLEVNPQNKAARLQIS 392 ++ ++ A DF+K E++P+N +Q++ Sbjct: 315 FILQNYDQAGKDFDKAKELDPENIFPYIQLA 345 Score = 40.8 bits (94), Expect = 0.001, Method: Compositional matrix adjust. Identities = 38/119 (31%), Positives = 51/119 (42%), Gaps = 17/119 (14%) Query: 263 EKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYGLSEKESKASESFLLAAFLN 322 EK + A +K+KG +F+ KY A+ Y W L KE S N Sbjct: 1 EKDKYALALKDKGNQFFRNKKYDDAIKYYN----W-----ALELKEDPVFYS-------N 44 Query: 323 LAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEVN 381 L+ CY+ + + K VE KAL L K L RR A + +F A D VL +N Sbjct: 45 LSACYVSVGDLKKVVEMSTKALELKPDYSKVLLRRASANEGLGKFADAMFDL-SVLSLN 102 >5XB0-A nrPDB Length = 133 Score = 44.3 bits (103), Expect = 1e-04, Method: Composition-based stats. Identities = 43/132 (32%), Positives = 58/132 (43%), Gaps = 13/132 (9%) Query: 12 ESPT--ATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDK------VYVHYKGKLSN 63 ++PT A AE+ K GV ++ + E TP G K V V Y G+L + Sbjct: 3 DAPTEAALKAERTFMAGEKAKPGVKELADGILMTELTPGTGPKPDANGRVEVRYVGRLPD 62 Query: 64 GKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLPKIP 123 GK FD S +P F L VI W + M G L+ + AYG+ G+ I Sbjct: 63 GKIFDQS---TQPQWFRLD--SVISGWTSALQNMPTGAKWRLVIPSDQAYGAEGAGDLID 117 Query: 124 SNATLFFEIELL 135 L FEIEL+ Sbjct: 118 PFTPLVFEIELI 129 >1IX5-A nrPDB Length = 151 Score = 42.4 bits (98), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 31/92 (33%), Positives = 46/92 (50%), Gaps = 15/92 (16%) Query: 50 GDKVYVHYKGKLSNGKKFDSS------------HDRN-EPFVFSLGKGQVIKAWDIGVAT 96 G K+ V Y GKL +G FD+S DR EP F +G+GQ+I+ ++ V Sbjct: 5 GVKIKVDYIGKLESGDVFDTSIEEVAKEAGIYAPDREYEPLEFVVGEGQLIQGFEEAVLD 64 Query: 97 MKKGEICHLLCKPEYAYGSAGSL--PKIPSNA 126 M+ G+ + E AYG+ + KIP +A Sbjct: 65 MEVGDEKTVKIPAEKAYGNRNEMLIQKIPRDA 96 >2LKN-A nrPDB Length = 165 Score = 41.6 bits (96), Expect = 7e-04, Method: Compositional matrix adjust. Identities = 29/88 (32%), Positives = 43/88 (48%), Gaps = 4/88 (4%) Query: 24 DITSK-KDRGVLKIVKRVGNGEETPMI-GDKVYVHYKGKLSN--GKKFDSSHDRNEPFVF 79 DI ++ ++ G+ K V + G GE G K HY+ S+ G D S R +P Sbjct: 2 DIIARLREDGIQKRVIQEGRGELPDFQDGTKATFHYRTLHSDDEGTVLDDSRARGKPMEL 61 Query: 80 SLGKGQVIKAWDIGVATMKKGEICHLLC 107 +GK + W+ V TM++GEI LC Sbjct: 62 IIGKKFKLPVWETIVCTMREGEIAQFLC 89 >4I2W-A nrPDB Length = 961 Score = 40.4 bits (93), Expect = 0.002, Method: Compositional matrix adjust. Identities = 36/141 (25%), Positives = 66/141 (46%), Gaps = 13/141 (9%) Query: 264 KLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYGLSEKESKASESFLLAAFLNL 323 +++ A ++++G K Y++A Y + + L+ E KA L + N Sbjct: 4 RVQTAEEIRDEGNAAVKDQDYIKADELYTEALQ-------LTTDEDKALRPVL---YRNR 53 Query: 324 AMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEVNPQ 383 AM LK ++ A C KAL D A+ K L+RR A+ + A D ++ L ++P Sbjct: 54 AMARLKRDDFEGAQSDCTKALEFDGADVKALFRRSLAREQLGNVGPAFQDAKEALRLSPN 113 Query: 384 NKAARLQISMCQKKAKEHNER 404 +K + + Q+ K +N++ Sbjct: 114 DKGI---VEVLQRLVKANNDK 131 >2Y4T-A nrPDB Length = 450 Score = 37.0 bits (84), Expect = 0.019, Method: Compositional matrix adjust. Identities = 28/127 (22%), Positives = 56/127 (44%), Gaps = 11/127 (8%) Query: 279 FKGGKYMQAVIQYGKIVSWLEMEYGLSEKESKASESFLLAAFLNLAMCYLKLREYTKAVE 338 + G+Y A +Y + ++ E ++E ++ E + C+ K + +A+ Sbjct: 268 IRDGRYTDATSKYESV---MKTEPSIAEYTVRSKE--------RICHCFSKDEKPVEAIR 316 Query: 339 CCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEVNPQNKAARLQISMCQKKA 398 C + L ++ N L R EA L+ ++ A D+E E N ++ R + Q+ Sbjct: 317 VCSEVLQMEPDNVNALKDRAEAYLIEEMYDEAIQDYETAQEHNENDQQIREGLEKAQRLL 376 Query: 399 KEHNERD 405 K+ +RD Sbjct: 377 KQSQKRD 383 >4CGU-A nrPDB Length = 112 Score = 33.9 bits (76), Expect = 0.16, Method: Composition-based stats. Identities = 24/80 (30%), Positives = 39/80 (48%), Gaps = 15/80 (18%) Query: 272 KEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYGLSEKESKASESFLLAAFLNLAMCYLKLR 331 KE+G FK G Y +AV Y ++++ ++ ++ S N AM +KL Sbjct: 9 KEQGNSLFKQGLYREAVHCYDQLIT--------AQPQNPVGYS-------NKAMALIKLG 53 Query: 332 EYTKAVECCDKALGLDSANE 351 EYT+A++ C + L S E Sbjct: 54 EYTQAIQMCQQGLRYTSTAE 73 >5G04-F nrPDB Length = 824 Score = 32.0 bits (71), Expect = 0.54, Method: Compositional matrix adjust. Identities = 20/82 (24%), Positives = 36/82 (43%) Query: 319 AFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVL 378 A+ L ++ E KA+ C A+ ++ + Y G +F A+ F+K L Sbjct: 603 AYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKAL 662 Query: 379 EVNPQNKAARLQISMCQKKAKE 400 ++NPQ+ I + Q K+ Sbjct: 663 DINPQSSVLLCHIGVVQHALKK 684 Score = 30.0 bits (66), Expect = 2.4, Method: Compositional matrix adjust. Identities = 30/121 (24%), Positives = 49/121 (40%), Gaps = 13/121 (10%) Query: 283 KYMQAVIQ----YGKIVSWLEMEYGLSEKESKASESFLLA---------AFLNLAMCYLK 329 K+ Q IQ Y + L E+ L+E+ KA F A A+ L M Y K Sbjct: 588 KFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYK 647 Query: 330 LREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEVNPQNKAARL 389 +++ A KAL ++ + L G Q + + E A K + ++P+N + Sbjct: 648 QEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKF 707 Query: 390 Q 390 Sbjct: 708 H 708 >2OGG-A nrPDB Length = 152 Score = 30.4 bits (67), Expect = 1.5, Method: Composition-based stats. Identities = 20/74 (27%), Positives = 37/74 (50%), Gaps = 2/74 (2%) Query: 232 KFGIEPNAELIYEVTLKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQY 291 KFG+EP +ELI + + + + WE+ K++ ++ +K + K ++ I Sbjct: 15 KFGLEPPSELIQKQLRANLD--DDIWEVIRSRKIDGEHVILDKDYFFRKHVPHLTKEICE 72 Query: 292 GKIVSWLEMEYGLS 305 I ++E E GLS Sbjct: 73 NSIYEYIEGELGLS 86 >2KR7-A nrPDB Length = 151 Score = 30.0 bits (66), Expect = 2.2, Method: Compositional matrix adjust. Identities = 29/110 (26%), Positives = 47/110 (42%), Gaps = 15/110 (13%) Query: 70 SHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYG--SAGSLPKIPSNAT 127 S+ EP F +G Q+I + V + GE ++ PE AYG + L ++P + Sbjct: 30 SNISKEPLEFIIGTNQIIAGLEKAVLKAQIGEWEEVVIAPEEAYGVYESSYLQEVPRDQF 89 Query: 128 LFFEIELLDFKGEDLF---EDGGIIRRTKRKGEG------YSNPNEGATV 168 E+E KG +F ED I+ + Y++P G T+ Sbjct: 90 EGIELE----KGMSVFGQTEDNQTIQAIIKDFSATHVMVDYNHPLAGKTL 135 >3PRB-A nrPDB Length = 231 Score = 29.6 bits (65), Expect = 2.9, Method: Compositional matrix adjust. Identities = 21/78 (26%), Positives = 34/78 (43%), Gaps = 14/78 (17%) Query: 50 GDKVYVHYKGKLSNGKKFDSSHDRNE-------------PFVFSLGKGQVIKAWDIGVAT 96 G V + Y G + +GK FD++++ P G+GQV+ D + Sbjct: 5 GKMVKISYDGYV-DGKLFDTTNEELAKKEGIYNPAMIYGPVAIFAGEGQVLPGLDEAILE 63 Query: 97 MKKGEICHLLCKPEYAYG 114 M GE ++ PE A+G Sbjct: 64 MDVGEEREVVLPPEKAFG 81 Score = 28.5 bits (62), Expect = 6.7, Method: Compositional matrix adjust. Identities = 24/95 (25%), Positives = 40/95 (42%), Gaps = 21/95 (22%) Query: 165 GATVEIHLEGRCGGRMFDCRD------------------VAFTVGEGEDHDIPIGIDKAL 206 G V+I +G G++FD + VA GEG+ + G+D+A+ Sbjct: 5 GKMVKISYDGYVDGKLFDTTNEELAKKEGIYNPAMIYGPVAIFAGEGQ---VLPGLDEAI 61 Query: 207 EKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAEL 241 +M E+ + L P FG+ K + P +E Sbjct: 62 LEMDVGEEREVVLPPEKAFGKRDPSKIKLIPLSEF 96 >2Q2E-B nrPDB Length = 621 Score = 28.9 bits (63), Expect = 4.4, Method: Compositional matrix adjust. Identities = 25/72 (34%), Positives = 32/72 (44%), Gaps = 4/72 (5%) Query: 300 MEYGLSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGE 359 +E G K +E LA FL + C + L A E C KA GLD + R E Sbjct: 241 IELGTLMKMLHYTERQKLAPFLRYSFCKIGL---LTAEEIC-KAAGLDPEIDPHALGRHE 296 Query: 360 AQLLMNEFESAK 371 A+ L+ FE K Sbjct: 297 ARKLIEAFEKVK 308 >6AF0-A nrPDB Length = 939 Score = 28.9 bits (63), Expect = 4.6, Method: Compositional matrix adjust. Identities = 19/85 (22%), Positives = 42/85 (49%), Gaps = 9/85 (10%) Query: 320 FLNLAMCYLKLREYTKAVECCDKALGLD-SANEKGL--------YRRGEAQLLMNEFESA 370 ++N+ Y +LR+++KA+E + AL + AN+ G+ +G A+ ++ ++ A Sbjct: 776 YVNMGHIYAELRQFSKAIESYEIALSKEGKANDAGIISCLGRTWLNKGRAERNLDAYKMA 835 Query: 371 KGDFEKVLEVNPQNKAARLQISMCQ 395 +K + V P + ++ Q Sbjct: 836 LDQAKKAVAVAPDQLHFKFNVAFVQ 860 >3PRA-A nrPDB Length = 157 Score = 28.9 bits (63), Expect = 5.0, Method: Compositional matrix adjust. Identities = 21/78 (26%), Positives = 34/78 (43%), Gaps = 14/78 (17%) Query: 50 GDKVYVHYKGKLSNGKKFDSSHDRNE-------------PFVFSLGKGQVIKAWDIGVAT 96 G V + Y G + +GK FD++++ P G+GQV+ D + Sbjct: 5 GKMVKISYDGYV-DGKLFDTTNEELAKKEGIYNPAMIYGPVAIFAGEGQVLPGLDEAILE 63 Query: 97 MKKGEICHLLCKPEYAYG 114 M GE ++ PE A+G Sbjct: 64 MDVGEEREVVLPPEKAFG 81 >5UDI-A nrPDB Length = 479 Score = 28.5 bits (62), Expect = 5.6, Method: Compositional matrix adjust. Identities = 12/18 (66%), Positives = 15/18 (83%) Query: 367 FESAKGDFEKVLEVNPQN 384 +E AK FEKVLEV+P+N Sbjct: 158 YERAKACFEKVLEVDPEN 175 >5DSE-A nrPDB Length = 837 Score = 28.5 bits (62), Expect = 5.7, Method: Compositional matrix adjust. Identities = 16/65 (24%), Positives = 32/65 (49%) Query: 320 FLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLE 379 +L+ A Y+ + + +A C +A L + LY RG+ L + A+ +E+ L Sbjct: 693 WLHAAEVYIGIGKPAEATACTQEAANLFPMSHNVLYMRGQIAELRGSMDEARRWYEEALA 752 Query: 380 VNPQN 384 ++P + Sbjct: 753 ISPTH 757 >4HOU-A nrPDB Length = 273 Score = 28.5 bits (62), Expect = 5.8, Method: Compositional matrix adjust. Identities = 12/18 (66%), Positives = 15/18 (83%) Query: 367 FESAKGDFEKVLEVNPQN 384 +E AK FEKVLEV+P+N Sbjct: 151 YERAKACFEKVLEVDPEN 168 >4JYS-A nrPDB Length = 138 Score = 28.1 bits (61), Expect = 8.6, Method: Composition-based stats. Identities = 16/37 (43%), Positives = 24/37 (64%), Gaps = 3/37 (8%) Query: 28 KKDRGVLKIVKRVGNGEETPMI-GDKVYVHYKGKLSN 63 K + G+L K + +GE P+ GD VY+HY+GK +N Sbjct: 10 KTESGIL--YKDLIDGEGDPIEEGDIVYIHYQGKTTN 44 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 5OMP-A nrPDB 635 0.0 1KT1-A nrPDB 634 0.0 3O5D-A nrPDB 387 e-108 1QZ2-A nrPDB 371 e-103 1Q1C-A nrPDB 361 e-100 4TW8-A nrPDB 333 8e-92 5MGX-E nrPDB 305 3e-83 3JXV-A nrPDB 253 1e-67 2IF4-A nrPDB 240 1e-63 3O5E-A nrPDB 220 1e-57 4DRJ-A nrPDB 215 3e-56 1ROT-A nrPDB 211 7e-55 4R0X-A nrPDB 194 6e-50 1R9H-A nrPDB 184 6e-47 1IHG-A nrPDB 174 8e-44 6B4P-A nrPDB 169 2e-42 5HWB-A nrPDB 169 2e-42 2ND5-A nrPDB 168 6e-42 3UQI-A nrPDB 166 2e-41 5HUA-A nrPDB 164 5e-41 2Y78-A nrPDB 164 5e-41 1YAT-A nrPDB 164 6e-41 2L2S-A nrPDB 164 9e-41 2LGO-A nrPDB 159 2e-39 5T9S-F nrPDB 159 3e-39 5JHE-A nrPDB 159 3e-39 4GIV-A nrPDB 157 1e-38 5L1D-B nrPDB 157 1e-38 3IHZ-A nrPDB 156 2e-38 4NNR-A nrPDB 154 5e-38 2MPH-A nrPDB 153 1e-37 4QT3-A nrPDB 151 6e-37 2PBC-A nrPDB 144 6e-35 5HW8-A nrPDB 143 2e-34 5B8I-C nrPDB 142 2e-34 3B7X-A nrPDB 139 2e-33 4JA9-A nrPDB 138 5e-33 4I2W-A nrPDB 137 7e-33 6FO1-G nrPDB 137 1e-32 1JVW-A nrPDB 136 2e-32 5D75-A nrPDB 134 9e-32 5JJT-A nrPDB 133 2e-31 2D9F-A nrPDB 131 9e-31 5I7Q-A nrPDB 131 1e-30 2VCD-A nrPDB 130 1e-30 5I7P-A nrPDB 129 3e-30 1Y0O-A nrPDB 128 5e-30 3EY6-A nrPDB 128 6e-30 2MF9-A nrPDB 127 8e-30 1FD9-A nrPDB 127 1e-29 1A17-A nrPDB 125 4e-29 5XB0-A nrPDB 122 2e-28 4BF8-A nrPDB 118 6e-27 4DIP-A nrPDB 116 2e-26 4MSP-A nrPDB 116 2e-26 2C2L-A nrPDB 115 4e-26 1Q6H-A nrPDB 113 2e-25 2F4E-A nrPDB 113 2e-25 2GW1-A nrPDB 94 1e-19 6H3J-B nrPDB 92 6e-19 2LKN-A nrPDB 87 2e-17 1IX5-A nrPDB 77 2e-14 Sequences not found previously or not previously below threshold: 2Y4T-A nrPDB 72 5e-13 4ODP-A nrPDB 67 2e-11 4DT4-A nrPDB 59 3e-09 2M2A-A nrPDB 59 3e-09 3PRA-A nrPDB 58 9e-09 6B85-J nrPDB 57 2e-08 3PRB-A nrPDB 57 2e-08 5AEM-A nrPDB 55 9e-08 5G04-F nrPDB 54 1e-07 4JYS-A nrPDB 54 2e-07 5U9A-A nrPDB 52 4e-07 4CGU-A nrPDB 52 7e-07 5WQL-B nrPDB 51 1e-06 1W3B-A nrPDB 51 1e-06 5FZQ-A nrPDB 49 6e-06 5OJ8-A nrPDB 44 2e-04 5NNP-A nrPDB 44 2e-04 1HH8-A nrPDB 44 2e-04 2KR7-A nrPDB 43 2e-04 6FUZ-A nrPDB 43 3e-04 3NF1-A nrPDB 43 4e-04 5DSE-A nrPDB 41 9e-04 3CGM-A nrPDB 40 0.002 5OJF-A nrPDB 40 0.002 4I9E-A nrPDB 40 0.003 4I1A-A nrPDB 39 0.003 6C95-A nrPDB 39 0.003 4HOQ-A nrPDB 39 0.004 3ZFW-A nrPDB 39 0.004 2KFW-A nrPDB 39 0.006 2K8I-A nrPDB 39 0.006 4GYO-A nrPDB 38 0.007 3H4Z-A nrPDB 38 0.007 4UZY-A nrPDB 38 0.008 5A01-A nrPDB 37 0.012 5ZYQ-A nrPDB 37 0.014 5LVV-A nrPDB 37 0.017 1HXV-A nrPDB 37 0.018 6D6S-A nrPDB 34 0.17 5ZR0-A nrPDB 34 0.19 5O09-1C nrPDB 33 0.25 6AF0-A nrPDB 33 0.27 3AHY-A nrPDB 33 0.34 1L1P-A nrPDB 32 0.38 5UDI-A nrPDB 32 0.45 4G1T-A nrPDB 32 0.48 4HOU-A nrPDB 32 0.48 1QQE-A nrPDB 32 0.50 6AHD-N nrPDB 31 1.2 5CTQ-A nrPDB 30 1.4 5CTR-A nrPDB 30 1.6 1H4S-A nrPDB 30 1.6 4KVO-A nrPDB 30 1.7 6N3Q-F nrPDB 30 2.0 1ZU2-A nrPDB 30 2.1 5LJ5-S nrPDB 30 2.7 3EHU-A nrPDB 30 2.8 5NPF-A nrPDB 29 4.9 >5OMP-A nrPDB Length = 462 Score = 635 bits (1638), Expect = 0.0, Method: Composition-based stats. Identities = 457/457 (100%), Positives = 457/457 (100%) Query: 1 MTTDEGAKNNEESPTATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGK 60 MTTDEGAKNNEESPTATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGK Sbjct: 6 MTTDEGAKNNEESPTATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGK 65 Query: 61 LSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLP 120 LSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLP Sbjct: 66 LSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLP 125 Query: 121 KIPSNATLFFEIELLDFKGEDLFEDGGIIRRTKRKGEGYSNPNEGATVEIHLEGRCGGRM 180 KIPSNATLFFEIELLDFKGEDLFEDGGIIRRTKRKGEGYSNPNEGATVEIHLEGRCGGRM Sbjct: 126 KIPSNATLFFEIELLDFKGEDLFEDGGIIRRTKRKGEGYSNPNEGATVEIHLEGRCGGRM 185 Query: 181 FDCRDVAFTVGEGEDHDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAE 240 FDCRDVAFTVGEGEDHDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAE Sbjct: 186 FDCRDVAFTVGEGEDHDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAE 245 Query: 241 LIYEVTLKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEM 300 LIYEVTLKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEM Sbjct: 246 LIYEVTLKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEM 305 Query: 301 EYGLSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEA 360 EYGLSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEA Sbjct: 306 EYGLSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEA 365 Query: 361 QLLMNEFESAKGDFEKVLEVNPQNKAARLQISMCQKKAKEHNERDRRIYANMFKKFAEQD 420 QLLMNEFESAKGDFEKVLEVNPQNKAARLQISMCQKKAKEHNERDRRIYANMFKKFAEQD Sbjct: 366 QLLMNEFESAKGDFEKVLEVNPQNKAARLQISMCQKKAKEHNERDRRIYANMFKKFAEQD 425 Query: 421 AKEEANKAMGKKTSEGVTNEKGTDSQAMEEEKPEGHV 457 AKEEANKAMGKKTSEGVTNEKGTDSQAMEEEKPEGHV Sbjct: 426 AKEEANKAMGKKTSEGVTNEKGTDSQAMEEEKPEGHV 462 >1KT1-A nrPDB Length = 457 Score = 634 bits (1634), Expect = 0.0, Method: Composition-based stats. Identities = 429/457 (93%), Positives = 444/457 (97%) Query: 1 MTTDEGAKNNEESPTATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGK 60 MTTDEGAKN+ +P ATVAEQGED+TSKKDRGVLKIVKRVG+GEETPMIGD+VYVHY GK Sbjct: 1 MTTDEGAKNSRGNPAATVAEQGEDVTSKKDRGVLKIVKRVGHGEETPMIGDRVYVHYNGK 60 Query: 61 LSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLP 120 L+NGKKFDSSHDRNEPFVFS+GKGQVIKAWDIGVATMKKGEICHLLCKPEYAYG+ GSLP Sbjct: 61 LANGKKFDSSHDRNEPFVFSIGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGATGSLP 120 Query: 121 KIPSNATLFFEIELLDFKGEDLFEDGGIIRRTKRKGEGYSNPNEGATVEIHLEGRCGGRM 180 KIPSNATLFFE+ELLDFKGEDL EDGGIIRRTKR+GEGYSNPNEGA V+IHLEGRCGGR+ Sbjct: 121 KIPSNATLFFEVELLDFKGEDLLEDGGIIRRTKRRGEGYSNPNEGARVQIHLEGRCGGRV 180 Query: 181 FDCRDVAFTVGEGEDHDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAE 240 FDCRDVAFTVGEGEDHDIPIGIDKALEKMQREEQCIL+LGPRYGFGEAGKPKFGIEPNAE Sbjct: 181 FDCRDVAFTVGEGEDHDIPIGIDKALEKMQREEQCILHLGPRYGFGEAGKPKFGIEPNAE 240 Query: 241 LIYEVTLKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEM 300 LIYEVTLKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKY+QAVIQYGKIVSWLEM Sbjct: 241 LIYEVTLKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYVQAVIQYGKIVSWLEM 300 Query: 301 EYGLSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEA 360 EYGLSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEA Sbjct: 301 EYGLSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEA 360 Query: 361 QLLMNEFESAKGDFEKVLEVNPQNKAARLQISMCQKKAKEHNERDRRIYANMFKKFAEQD 420 QLLMNEFESAKGDFEKVLEVNPQNKAARLQI MCQKKAKEHNERDRR YANMFKKFAEQD Sbjct: 361 QLLMNEFESAKGDFEKVLEVNPQNKAARLQIFMCQKKAKEHNERDRRTYANMFKKFAEQD 420 Query: 421 AKEEANKAMGKKTSEGVTNEKGTDSQAMEEEKPEGHV 457 AKEEANKAM KKTSEGVTNEK T S A+EEEKPEGHV Sbjct: 421 AKEEANKAMSKKTSEGVTNEKLTASHAVEEEKPEGHV 457 >3O5D-A nrPDB Length = 264 Score = 387 bits (994), Expect = e-108, Method: Composition-based stats. Identities = 260/260 (100%), Positives = 260/260 (100%) Query: 1 MTTDEGAKNNEESPTATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGK 60 MTTDEGAKNNEESPTATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGK Sbjct: 5 MTTDEGAKNNEESPTATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGK 64 Query: 61 LSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLP 120 LSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLP Sbjct: 65 LSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLP 124 Query: 121 KIPSNATLFFEIELLDFKGEDLFEDGGIIRRTKRKGEGYSNPNEGATVEIHLEGRCGGRM 180 KIPSNATLFFEIELLDFKGEDLFEDGGIIRRTKRKGEGYSNPNEGATVEIHLEGRCGGRM Sbjct: 125 KIPSNATLFFEIELLDFKGEDLFEDGGIIRRTKRKGEGYSNPNEGATVEIHLEGRCGGRM 184 Query: 181 FDCRDVAFTVGEGEDHDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAE 240 FDCRDVAFTVGEGEDHDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAE Sbjct: 185 FDCRDVAFTVGEGEDHDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAE 244 Query: 241 LIYEVTLKSFEKAKESWEMD 260 LIYEVTLKSFEKAKESWEMD Sbjct: 245 LIYEVTLKSFEKAKESWEMD 264 >1QZ2-A nrPDB Length = 336 Score = 371 bits (953), Expect = e-103, Method: Composition-based stats. Identities = 166/319 (52%), Positives = 236/319 (73%), Gaps = 6/319 (1%) Query: 138 KGEDLFEDGGIIRRTKRKGEGYSNPNEGATVEIHLEGRCGGRMFDCRDVAFTVGEGEDHD 197 +G + EDGGIIRR + +GEGY+ PNEGA VE+ LEG ++FD R++ F +GEGE+ D Sbjct: 17 RGSHMEEDGGIIRRIQTRGEGYAKPNEGAIVEVALEGYYKDKLFDQRELRFEIGEGENLD 76 Query: 198 IPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTLKSFEKAKESW 257 +P G+++A+++M++ E I+YL P Y FG GK KF I PNAEL YE+ LKSFEKAKESW Sbjct: 77 LPYGLERAIQRMEKGEHSIVYLKPSYAFGSVGKEKFQIPPNAELKYELHLKSFEKAKESW 136 Query: 258 EMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYGLSEKESKASESFLL 317 EM+++EKLEQ+ IVKE+GTVYFK GKY QA++QY KIVSWLE E S +E++ +++ L Sbjct: 137 EMNSEEKLEQSTIVKERGTVYFKEGKYKQALLQYKKIVSWLEYESSFSNEEAQKAQALRL 196 Query: 318 AAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKV 377 A+ LNLAMC+LKL+ ++ A+E C+KAL LDS NEKGL+RRGEA L +N+FE A+ DF+KV Sbjct: 197 ASHLNLAMCHLKLQAFSAAIESCNKALELDSNNEKGLFRRGEAHLAVNDFELARADFQKV 256 Query: 378 LEVNPQNKAARLQISMCQKKAKEHNERDRRIYANMFKKFAEQDAKEEANKAMGKKTS--- 434 L++ P NKAA+ Q+++CQ++ + R++++YANMF++ AE++ K +A + G + Sbjct: 257 LQLYPNNKAAKTQLAVCQQRIRRQLAREKKLYANMFERLAEEENKAKAEASSGDHPTDTE 316 Query: 435 ---EGVTNEKGTDSQAMEE 450 E +N G+ SQ E Sbjct: 317 MKEEQKSNTAGSQSQVETE 335 Score = 94.8 bits (234), Expect = 7e-20, Method: Composition-based stats. Identities = 40/149 (26%), Positives = 67/149 (44%), Gaps = 14/149 (9%) Query: 26 TSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQ 85 ++D G+++ ++ G G P G V V +G + K FD R F +G+G+ Sbjct: 20 HMEEDGGIIRRIQTRGEGYAKPNEGAIVEVALEGYYKD-KLFDQRELR-----FEIGEGE 73 Query: 86 VIK---AWDIGVATMKKGEICHLLCKPEYAYGSAGSLP-KIPSNATLFFEIELLDFKGE- 140 + + + M+KGE + KP YA+GS G +IP NA L +E+ L F+ Sbjct: 74 NLDLPYGLERAIQRMEKGEHSIVYLKPSYAFGSVGKEKFQIPPNAELKYELHLKSFEKAK 133 Query: 141 ---DLFEDGGIIRRTKRKGEGYSNPNEGA 166 ++ + + + T K G EG Sbjct: 134 ESWEMNSEEKLEQSTIVKERGTVYFKEGK 162 >1Q1C-A nrPDB Length = 280 Score = 361 bits (927), Expect = e-100, Method: Composition-based stats. Identities = 155/260 (59%), Positives = 195/260 (75%), Gaps = 2/260 (0%) Query: 1 MTTDEGAKNNEESPTATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGK 60 MT +E + +A + +G DI+ K+D GVLK++KR G G E PMIGD+V+VHY G Sbjct: 21 MTAEEMKATESGAQSAPLPMEGVDISPKQDEGVLKVIKREGTGTEMPMIGDRVFVHYTGW 80 Query: 61 LSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLP 120 L +G KFDSS DR + F F LGKG+VIKAWDI +ATMK GE+CH+ CKPEYAYGSAGS P Sbjct: 81 LLDGTKFDSSLDRKDKFSFDLGKGEVIKAWDIAIATMKVGEVCHITCKPEYAYGSAGSPP 140 Query: 121 KIPSNATLFFEIELLDFKGEDLF--EDGGIIRRTKRKGEGYSNPNEGATVEIHLEGRCGG 178 KIP NATL FE+EL +FKGEDL EDGGIIRR + +GEGY+ PNEGA VE+ LEG Sbjct: 141 KIPPNATLVFEVELFEFKGEDLTEEEDGGIIRRIQTRGEGYAKPNEGAIVEVALEGYYKD 200 Query: 179 RMFDCRDVAFTVGEGEDHDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPN 238 ++FD R++ F +GEGE+ D+P G+++A+++M++ E I+YL P Y FG GK KF I PN Sbjct: 201 KLFDQRELRFEIGEGENLDLPYGLERAIQRMEKGEHSIVYLKPSYAFGSVGKEKFQIPPN 260 Query: 239 AELIYEVTLKSFEKAKESWE 258 AEL YE+ LKSFEKAKESWE Sbjct: 261 AELKYELHLKSFEKAKESWE 280 Score = 143 bits (360), Expect = 2e-34, Method: Composition-based stats. Identities = 45/154 (29%), Positives = 70/154 (45%), Gaps = 16/154 (10%) Query: 135 LDFKGEDLF--EDGGIIRRTKRKGEGYSNPNEGATVEIHLEGRC-GGRMFDCR-----DV 186 L +G D+ +D G+++ KR+G G P G V +H G G FD Sbjct: 38 LPMEGVDISPKQDEGVLKVIKREGTGTEMPMIGDRVFVHYTGWLLDGTKFDSSLDRKDKF 97 Query: 187 AFTVGEGEDHDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVT 246 +F +G+GE + D A+ M+ E C + P Y +G AG P I PNA L++EV Sbjct: 98 SFDLGKGE---VIKAWDIAIATMKVGEVCHITCKPEYAYGSAGSPP-KIPPNATLVFEVE 153 Query: 247 LKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFK 280 L F+ ++ +E ++ +G Y K Sbjct: 154 LFEFKG----EDLTEEEDGGIIRRIQTRGEGYAK 183 >4TW8-A nrPDB Length = 235 Score = 333 bits (854), Expect = 8e-92, Method: Composition-based stats. Identities = 146/235 (62%), Positives = 182/235 (77%), Gaps = 2/235 (0%) Query: 21 QGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFS 80 +G DI+ K+D GVLK++KR G G E PMIGD+V+VHY G L +G KFDSS DR + F F Sbjct: 1 EGVDISPKQDEGVLKVIKREGTGTEMPMIGDRVFVHYTGWLLDGTKFDSSLDRKDKFSFD 60 Query: 81 LGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELLDFKGE 140 LGKG+VIKAWDI +ATMK GE+CH+ CKPEYAYGSAGS PKIP NATL FE+EL +FKGE Sbjct: 61 LGKGEVIKAWDIAIATMKVGEVCHITCKPEYAYGSAGSPPKIPPNATLVFEVELFEFKGE 120 Query: 141 DLF--EDGGIIRRTKRKGEGYSNPNEGATVEIHLEGRCGGRMFDCRDVAFTVGEGEDHDI 198 DL EDGGIIRR + +GEGY+ PNEGA VE+ LEG ++FD R++ F +GEGE+ D+ Sbjct: 121 DLTEEEDGGIIRRIQTRGEGYAKPNEGAIVEVALEGYYKDKLFDQRELRFEIGEGENLDL 180 Query: 199 PIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTLKSFEKA 253 P G+++A+++M++ E I+YL P Y FG GK KF I PNAEL YE+ LKSFEKA Sbjct: 181 PYGLERAIQRMEKGEHSIVYLKPSYAFGSVGKEKFQIPPNAELKYELHLKSFEKA 235 Score = 142 bits (359), Expect = 2e-34, Method: Composition-based stats. Identities = 44/151 (29%), Positives = 69/151 (45%), Gaps = 16/151 (10%) Query: 138 KGEDLF--EDGGIIRRTKRKGEGYSNPNEGATVEIHLEGRC-GGRMFDCR-----DVAFT 189 +G D+ +D G+++ KR+G G P G V +H G G FD +F Sbjct: 1 EGVDISPKQDEGVLKVIKREGTGTEMPMIGDRVFVHYTGWLLDGTKFDSSLDRKDKFSFD 60 Query: 190 VGEGEDHDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTLKS 249 +G+GE + D A+ M+ E C + P Y +G AG P I PNA L++EV L Sbjct: 61 LGKGE---VIKAWDIAIATMKVGEVCHITCKPEYAYGSAGSPP-KIPPNATLVFEVELFE 116 Query: 250 FEKAKESWEMDTKEKLEQAAIVKEKGTVYFK 280 F+ ++ +E ++ +G Y K Sbjct: 117 FKG----EDLTEEEDGGIIRRIQTRGEGYAK 143 >5MGX-E nrPDB Length = 290 Score = 305 bits (781), Expect = 3e-83, Method: Composition-based stats. Identities = 68/287 (23%), Positives = 123/287 (42%), Gaps = 9/287 (3%) Query: 141 DLFEDGGIIRRTKRKGE-GYSNPNEGATVEIHLEGRC--GGRMFDCRDVAFTVGEGEDHD 197 D+ +G + ++T G G S P +G V +HL+ G R+ + ++ FT+G D D Sbjct: 5 DILGNGLLRKKTLVPGPPGSSRPVKGQVVTVHLQTSLENGTRVQEEPELVFTLG---DCD 61 Query: 198 IPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTLKSFEKAKESW 257 + +D ++ M E ++ +Y +G G+ + I P+A L EVTLK+ + Sbjct: 62 VIQALDLSVPLMDVGETAMVTADSKYCYGPQGRSPY-IPPHAALCLEVTLKTAVDGPDLE 120 Query: 258 EMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWL--EMEYGLSEKESKASESF 315 + +E++ A +E G +++ ++ A Y + + + ++ +E Sbjct: 121 MLTGQERVALANRKRECGNAHYQRADFVLAANSYDLAIKAITSSAKVDMTFEEEAQLLQL 180 Query: 316 LLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFE 375 + NLA LKL Y A+ C L N K L+R+G+ E+ A Sbjct: 181 KVKCLNNLAASQLKLDHYRAALRSCSLVLEHQPDNIKALFRKGKVLAQQGEYSEAIPILR 240 Query: 376 KVLEVNPQNKAARLQISMCQKKAKEHNERDRRIYANMFKKFAEQDAK 422 L++ P NK ++S KK + +Y M + AK Sbjct: 241 AALKLEPSNKTIHAELSKLVKKHAAQRSTETALYRKMLGNPSRLPAK 287 Score = 113 bits (283), Expect = 1e-25, Method: Composition-based stats. Identities = 37/102 (36%), Positives = 48/102 (47%), Gaps = 7/102 (6%) Query: 43 GEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEP-FVFSLGKGQVIKAWDIGVATMKKGE 101 G P+ G V VH + L NG + + EP VF+LG VI+A D+ V M GE Sbjct: 23 GSSRPVKGQVVTVHLQTSLENGTRV-----QEEPELVFTLGDCDVIQALDLSVPLMDVGE 77 Query: 102 ICHLLCKPEYAYGSAGSLPKIPSNATLFFEIEL-LDFKGEDL 142 + +Y YG G P IP +A L E+ L G DL Sbjct: 78 TAMVTADSKYCYGPQGRSPYIPPHAALCLEVTLKTAVDGPDL 119 >3JXV-A nrPDB Length = 356 Score = 253 bits (646), Expect = 1e-67, Method: Composition-based stats. Identities = 93/219 (42%), Positives = 134/219 (61%), Gaps = 10/219 (4%) Query: 44 EETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEIC 103 +TP +GD+V VHY G L +GKKFDSS DR++ F F LG+GQVIK WD G+ TMKKGE Sbjct: 24 WDTPEVGDEVEVHYTGTLLDGKKFDSSRDRDDTFKFKLGQGQVIKGWDQGIKTMKKGENA 83 Query: 104 HLLCKPEYAYGSAGSLPKIPSNATLFFEIELLDFKG-EDLFEDGGIIRRTKRKGEGYSNP 162 PE AYG +GS P IP+NATL F++ELL + D+ +DGGI ++ ++G+ + NP Sbjct: 84 LFTIPPELAYGESGSPPTIPANATLQFDVELLSWTSVRDIAKDGGIFKKILKEGDKWENP 143 Query: 163 NEGATVEIHLEGRC--GGRMFDCRDVAFTVGEGEDHDIPIGIDKALEKMQREEQCILYLG 220 + V + E R G + V FTV +G + KA++ M++ E+ +L + Sbjct: 144 KDPDEVFVKYEARLEDGTVVSKSEGVEFTVKDGHLCP---ALAKAVKTMKKGEKVLLAVK 200 Query: 221 PRYGFGEAGKPKFG----IEPNAELIYEVTLKSFEKAKE 255 P+YGFGE G+P G + PNA L+ ++ L S++ E Sbjct: 201 PQYGFGEMGRPAAGEGGAVPPNASLVIDLELVSWKTVTE 239 Score = 186 bits (473), Expect = 1e-47, Method: Composition-based stats. Identities = 72/239 (30%), Positives = 120/239 (50%), Gaps = 21/239 (8%) Query: 28 KKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVI 87 KD G+ K + + G+ E P D+V+V Y+ +L +G S E F++ G + Sbjct: 124 AKDGGIFKKILKEGDKWENPKDPDEVFVKYEARLEDGTVVSKS----EGVEFTVKDGHLC 179 Query: 88 KAWDIGVATMKKGEICHLLCKPEYAYGSAGSL-----PKIPSNATLFFEIELLDFKG-ED 141 A V TMKKGE L KP+Y +G G +P NA+L ++EL+ +K + Sbjct: 180 PALAKAVKTMKKGEKVLLAVKPQYGFGEMGRPAAGEGGAVPPNASLVIDLELVSWKTVTE 239 Query: 142 LFEDGGIIRRTKRKGEGYSNPNEGATVEIHLEGRC-GGRMF------DCRDVAFTVGEGE 194 + +D I+++ ++ EGY PNEGA V + + G+ G +F + F + Sbjct: 240 IGDDKKILKKVLKEXEGYERPNEGAVVTVKITGKLQDGTVFLKKGHDEQEPFEFKT---D 296 Query: 195 DHDIPIGIDKALEKMQREEQCILYLGPRYGFGE-AGKPKFGIEPNAELIYEVTLKSFEK 252 + + G+D+A+ M++ E ++ + P Y +G K + PN+ +IYEV L SF K Sbjct: 297 EEAVIEGLDRAVLNMKKGEVALVTIPPEYAYGSTESKQDAIVPPNSTVIYEVELVSFVK 355 >2IF4-A nrPDB Length = 338 Score = 240 bits (611), Expect = 1e-63, Method: Composition-based stats. Identities = 71/292 (24%), Positives = 140/292 (47%), Gaps = 12/292 (4%) Query: 145 DGGIIRRTKRKGEGYSNPNEGATVEIHLEGRCGGRMFDCRDV-----AFTVGEGEDHDIP 199 D + ++ ++G G S P++ +T +H D + G++ Sbjct: 48 DEKVSKQIIKEGHG-SKPSKYSTCFLHYRAWTKNSQHKFEDTWHEQQPIELVLGKEKKEL 106 Query: 200 IGIDKALEKMQREEQCILYLGPRYGFGEAGKPKF-GIEPNAELIYEVTLKSFEKAKE--- 255 G+ + M+ E+ ++++G +G+ G F + P A+L+YEV + F++ KE Sbjct: 107 AGLAIGVASMKSGERALVHVGWELAYGKEGNFSFPNVPPMADLLYEVEVIGFDETKEGKA 166 Query: 256 SWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWL--EMEYGLSEKESKASE 313 +M +E++ A K G FK K +A+ QY ++++ + + L K + Sbjct: 167 RSDMTVEERIGAADRRKMDGNSLFKEEKLEEAMQQYEMAIAYMGDDFMFQLYGKYQDMAL 226 Query: 314 SFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGD 373 + LN+A C +KL+ Y +A+ C+ L + N K L+RRG+A+ + + +SA+ D Sbjct: 227 AVKNPCHLNIAACLIKLKRYDEAIGHCNIVLTEEEKNPKALFRRGKAKAELGQMDSARDD 286 Query: 374 FEKVLEVNPQNKAARLQISMCQKKAKEHNERDRRIYANMFKKFAEQDAKEEA 425 F K + P +KA R ++ ++ K ++ + +Y +FK E AK ++ Sbjct: 287 FRKAQKYAPDDKAIRRELRALAEQEKALYQKQKEMYKGIFKGKDEGGAKSKS 338 Score = 111 bits (277), Expect = 8e-25, Method: Composition-based stats. Identities = 43/173 (24%), Positives = 73/173 (42%), Gaps = 5/173 (2%) Query: 1 MTTDEGAKNNEESPTATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGK 60 +T ++E S V + + D V K + + G+G P ++HY+ Sbjct: 19 VTEGSAVVHSEPSQEGNVPPKVDSEAEVLDEKVSKQIIKEGHGS-KPSKYSTCFLHYRAW 77 Query: 61 LSNGK-KFDSSHDRNEPFVFSLGK-GQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAG- 117 N + KF+ + +P LGK + + IGVA+MK GE + E AYG G Sbjct: 78 TKNSQHKFEDTWHEQQPIELVLGKEKKELAGLAIGVASMKSGERALVHVGWELAYGKEGN 137 Query: 118 -SLPKIPSNATLFFEIELLDFKGEDLFEDGGIIRRTKRKGEGYSNPNEGATVE 169 S P +P A L +E+E++ F + + +R G +G ++ Sbjct: 138 FSFPNVPPMADLLYEVEVIGFDETKEGKARSDMTVEERIGAADRRKMDGNSLF 190 >3O5E-A nrPDB Length = 144 Score = 220 bits (560), Expect = 1e-57, Method: Composition-based stats. Identities = 140/140 (100%), Positives = 140/140 (100%) Query: 1 MTTDEGAKNNEESPTATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGK 60 MTTDEGAKNNEESPTATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGK Sbjct: 5 MTTDEGAKNNEESPTATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGK 64 Query: 61 LSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLP 120 LSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLP Sbjct: 65 LSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLP 124 Query: 121 KIPSNATLFFEIELLDFKGE 140 KIPSNATLFFEIELLDFKGE Sbjct: 125 KIPSNATLFFEIELLDFKGE 144 Score = 134 bits (338), Expect = 6e-32, Method: Composition-based stats. Identities = 37/123 (30%), Positives = 59/123 (47%), Gaps = 12/123 (9%) Query: 138 KGEDLF--EDGGIIRRTKRKGEGYSNPNEGATVEIHLEGRCG-GRMFDC-----RDVAFT 189 +GED+ +D G+++ KR G G P G V +H +G+ G+ FD F+ Sbjct: 25 QGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFS 84 Query: 190 VGEGEDHDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTLKS 249 +G+G+ + D + M++ E C L P Y +G AG I NA L +E+ L Sbjct: 85 LGKGQ---VIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLP-KIPSNATLFFEIELLD 140 Query: 250 FEK 252 F+ Sbjct: 141 FKG 143 >4DRJ-A nrPDB Length = 144 Score = 215 bits (547), Expect = 3e-56, Method: Composition-based stats. Identities = 86/140 (61%), Positives = 105/140 (75%) Query: 1 MTTDEGAKNNEESPTATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGK 60 MT +E + +A + +G DI+ K+D GVLK++KR G G E PMIGD+V+VHY G Sbjct: 5 MTAEEMKATESGAQSAPLPMEGVDISPKQDEGVLKVIKREGTGTEMPMIGDRVFVHYTGW 64 Query: 61 LSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLP 120 L +G KFDSS DR + F F LGKG+VIKAWDI +ATMK GE+CH+ CKPEYAYGSAGS P Sbjct: 65 LLDGTKFDSSLDRKDKFSFDLGKGEVIKAWDIAIATMKVGEVCHITCKPEYAYGSAGSPP 124 Query: 121 KIPSNATLFFEIELLDFKGE 140 KIP NATL FE+EL +FKGE Sbjct: 125 KIPPNATLVFEVELFEFKGE 144 Score = 143 bits (361), Expect = 1e-34, Method: Composition-based stats. Identities = 41/126 (32%), Positives = 60/126 (47%), Gaps = 12/126 (9%) Query: 135 LDFKGEDLF--EDGGIIRRTKRKGEGYSNPNEGATVEIHLEGRC-GGRMFDCR-----DV 186 L +G D+ +D G+++ KR+G G P G V +H G G FD Sbjct: 22 LPMEGVDISPKQDEGVLKVIKREGTGTEMPMIGDRVFVHYTGWLLDGTKFDSSLDRKDKF 81 Query: 187 AFTVGEGEDHDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVT 246 +F +G+GE + D A+ M+ E C + P Y +G AG P I PNA L++EV Sbjct: 82 SFDLGKGE---VIKAWDIAIATMKVGEVCHITCKPEYAYGSAGSPP-KIPPNATLVFEVE 137 Query: 247 LKSFEK 252 L F+ Sbjct: 138 LFEFKG 143 >1ROT-A nrPDB Length = 149 Score = 211 bits (536), Expect = 7e-55, Method: Composition-based stats. Identities = 87/140 (62%), Positives = 105/140 (75%) Query: 7 AKNNEESPTATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGKLSNGKK 66 + +A + +G DI+ K+D GVLK++KR G G ETPMIGD+V+VHY G L +G K Sbjct: 6 KAAESGAQSAPLPLEGVDISPKQDEGVLKVIKREGTGTETPMIGDRVFVHYTGWLLDGTK 65 Query: 67 FDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLPKIPSNA 126 FDSS DR + F F LGKG+VIKAWDI VATMK GE+C + CKPEYAYGSAGS PKIP NA Sbjct: 66 FDSSLDRKDKFSFDLGKGEVIKAWDIAVATMKVGELCRITCKPEYAYGSAGSPPKIPPNA 125 Query: 127 TLFFEIELLDFKGEDLFEDG 146 TL FE+EL +FKGEDL +D Sbjct: 126 TLVFEVELFEFKGEDLTDDE 145 Score = 142 bits (357), Expect = 4e-34, Method: Composition-based stats. Identities = 42/135 (31%), Positives = 63/135 (46%), Gaps = 12/135 (8%) Query: 135 LDFKGEDLF--EDGGIIRRTKRKGEGYSNPNEGATVEIHLEGRC-GGRMFDCR-----DV 186 L +G D+ +D G+++ KR+G G P G V +H G G FD Sbjct: 17 LPLEGVDISPKQDEGVLKVIKREGTGTETPMIGDRVFVHYTGWLLDGTKFDSSLDRKDKF 76 Query: 187 AFTVGEGEDHDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVT 246 +F +G+GE + D A+ M+ E C + P Y +G AG P I PNA L++EV Sbjct: 77 SFDLGKGE---VIKAWDIAVATMKVGELCRITCKPEYAYGSAGSPP-KIPPNATLVFEVE 132 Query: 247 LKSFEKAKESWEMDT 261 L F+ + + D Sbjct: 133 LFEFKGEDLTDDEDG 147 >4R0X-A nrPDB Length = 122 Score = 194 bits (494), Expect = 6e-50, Method: Composition-based stats. Identities = 120/121 (99%), Positives = 120/121 (99%) Query: 20 EQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVF 79 EQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVF Sbjct: 2 EQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVF 61 Query: 80 SLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELLDFKG 139 SLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLP IPSNATLFFEIELLDFKG Sbjct: 62 SLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLPGIPSNATLFFEIELLDFKG 121 Query: 140 E 140 E Sbjct: 122 E 122 Score = 137 bits (345), Expect = 9e-33, Method: Composition-based stats. Identities = 38/123 (30%), Positives = 60/123 (48%), Gaps = 12/123 (9%) Query: 138 KGEDLF--EDGGIIRRTKRKGEGYSNPNEGATVEIHLEGRCG-GRMFDC-----RDVAFT 189 +GED+ +D G+++ KR G G P G V +H +G+ G+ FD F+ Sbjct: 3 QGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFS 62 Query: 190 VGEGEDHDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTLKS 249 +G+G+ + D + M++ E C L P Y +G AG GI NA L +E+ L Sbjct: 63 LGKGQ---VIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLP-GIPSNATLFFEIELLD 118 Query: 250 FEK 252 F+ Sbjct: 119 FKG 121 >1R9H-A nrPDB Length = 135 Score = 184 bits (468), Expect = 6e-47, Method: Composition-based stats. Identities = 71/132 (53%), Positives = 87/132 (65%), Gaps = 2/132 (1%) Query: 21 QGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFS 80 + DIT KKD GVLK++K+ G G P G V VHY G L NG KFDSS DR + F F+ Sbjct: 4 EKIDITPKKDGGVLKLIKKEGQGVVKPTTGTTVKVHYVGTLENGTKFDSSRDRGDQFSFN 63 Query: 81 LGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELLDFKGE 140 LG+G VIK WD+GVATM KGE+ + +Y YG AGS PKIP ATL FE+EL ++ E Sbjct: 64 LGRGNVIKGWDLGVATMTKGEVAEFTIRSDYGYGDAGSPPKIPGGATLIFEVELFEWSAE 123 Query: 141 DLF--EDGGIIR 150 D+ DG I+R Sbjct: 124 DISPDRDGTILR 135 Score = 129 bits (323), Expect = 3e-30, Method: Composition-based stats. Identities = 40/128 (31%), Positives = 61/128 (47%), Gaps = 14/128 (10%) Query: 141 DLF--EDGGIIRRTKRKGEGYSNPNEGATVEIHLEGRC-GGRMFDCR-----DVAFTVGE 192 D+ +DGG+++ K++G+G P G TV++H G G FD +F +G Sbjct: 7 DITPKKDGGVLKLIKKEGQGVVKPTTGTTVKVHYVGTLENGTKFDSSRDRGDQFSFNLGR 66 Query: 193 GEDHDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTLKSFEK 252 G ++ G D + M + E + YG+G+AG P I A LI+EV L FE Sbjct: 67 G---NVIKGWDLGVATMTKGEVAEFTIRSDYGYGDAGSPP-KIPGGATLIFEVEL--FEW 120 Query: 253 AKESWEMD 260 + E D Sbjct: 121 SAEDISPD 128 >1IHG-A nrPDB Length = 370 Score = 174 bits (441), Expect = 8e-44, Method: Composition-based stats. Identities = 45/166 (27%), Positives = 86/166 (51%), Gaps = 1/166 (0%) Query: 249 SFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYGLSEKE 308 F + + D + L + +K G +FK + A+ +Y K++ ++E +E Sbjct: 204 DFPEDADVDLKDVDKILLISEDLKNIGNTFFKSQNWEMAIKKYTKVLRYVEGSRAAAEDA 263 Query: 309 SKA-SESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEF 367 A + L+ LN+ C LK+ ++ AV+ C +AL +D +N K LYRR + + E+ Sbjct: 264 DGAKLQPVALSCVLNIGACKLKMSDWQGAVDSCLEALEIDPSNTKALYRRAQGWQGLKEY 323 Query: 368 ESAKGDFEKVLEVNPQNKAARLQISMCQKKAKEHNERDRRIYANMF 413 + A D +K E+ P++KA + ++ ++K K ++++ YA MF Sbjct: 324 DQALADLKKAQEIAPEDKAIQAELLKVKQKIKAQKDKEKAAYAKMF 369 >6B4P-A nrPDB Length = 127 Score = 169 bits (428), Expect = 2e-42, Method: Composition-based stats. Identities = 59/119 (49%), Positives = 80/119 (67%) Query: 20 EQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVF 79 + I +D+ + K + G+ +E P IG KV VHY G L++GKKFDSS DR +PFVF Sbjct: 9 MSTDWIPISQDQRLKKKIITAGSSDEQPPIGSKVSVHYTGTLTSGKKFDSSLDRGQPFVF 68 Query: 80 SLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELLDFK 138 +LGKG+VI+ WD+GV +MKKGE + +YAYG+ IP+N+TL FEIELL +K Sbjct: 69 TLGKGEVIRGWDLGVKSMKKGEKSYFEIPSDYAYGNNAIPGLIPANSTLMFEIELLSWK 127 Score = 111 bits (277), Expect = 8e-25, Method: Composition-based stats. Identities = 28/116 (24%), Positives = 52/116 (44%), Gaps = 10/116 (8%) Query: 142 LFEDGGIIRRTKRKGEGYSNPNEGATVEIHLEGRC-GGRMFDCR-----DVAFTVGEGED 195 + +D + ++ G P G+ V +H G G+ FD FT+G+GE Sbjct: 16 ISQDQRLKKKIITAGSSDEQPPIGSKVSVHYTGTLTSGKKFDSSLDRGQPFVFTLGKGE- 74 Query: 196 HDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTLKSFE 251 + G D ++ M++ E+ + Y +G P I N+ L++E+ L S++ Sbjct: 75 --VIRGWDLGVKSMKKGEKSYFEIPSDYAYGNNAIPGL-IPANSTLMFEIELLSWK 127 >5HWB-A nrPDB Length = 115 Score = 169 bits (428), Expect = 2e-42, Method: Composition-based stats. Identities = 56/107 (52%), Positives = 68/107 (63%) Query: 32 GVLKIVKRVGNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVIKAWD 91 GV K +K GNG + P GD V +HY G+L++G KFDSS DRNEPF +G G+VIK WD Sbjct: 5 GVTKELKSPGNGVDFPKKGDFVTIHYTGRLTDGSKFDSSVDRNEPFQTQIGTGRVIKGWD 64 Query: 92 IGVATMKKGEICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELLDFK 138 GV M GE L P+Y YG+ G P IP N+TL FE+ELL Sbjct: 65 EGVPQMSLGEKAVLTITPDYGYGARGFPPVIPGNSTLIFEVELLGIN 111 Score = 127 bits (320), Expect = 7e-30, Method: Composition-based stats. Identities = 35/107 (32%), Positives = 49/107 (45%), Gaps = 6/107 (5%) Query: 147 GIIRRTKRKGEGYSNPNEGATVEIHLEGRC-GGRMFDC---RDVAFTVGEGEDHDIPIGI 202 G+ + K G G P +G V IH GR G FD R+ F G + G Sbjct: 5 GVTKELKSPGNGVDFPKKGDFVTIHYTGRLTDGSKFDSSVDRNEPFQTQIGTGR-VIKGW 63 Query: 203 DKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTLKS 249 D+ + +M E+ +L + P YG+G G P I N+ LI+EV L Sbjct: 64 DEGVPQMSLGEKAVLTITPDYGYGARGFPPV-IPGNSTLIFEVELLG 109 >2ND5-A nrPDB Length = 111 Score = 168 bits (425), Expect = 6e-42, Method: Composition-based stats. Identities = 51/107 (47%), Positives = 64/107 (59%) Query: 32 GVLKIVKRVGNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVIKAWD 91 GV G+G P G VHY G L +GKKFDSS DRN+PF F LGK +VI+ W+ Sbjct: 5 GVQVETISPGDGRTFPKRGQTCVVHYTGMLEDGKKFDSSRDRNKPFKFMLGKQEVIRGWE 64 Query: 92 IGVATMKKGEICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELLDFK 138 GVA M G+ L P+YAYG+ G IP +ATL F++ELL + Sbjct: 65 EGVAQMSVGQRAKLTISPDYAYGATGHPGIIPPHATLVFDVELLKLE 111 Score = 114 bits (284), Expect = 1e-25, Method: Composition-based stats. Identities = 30/111 (27%), Positives = 51/111 (45%), Gaps = 10/111 (9%) Query: 147 GIIRRTKRKGEGYSNPNEGATVEIHLEGRC-GGRMFDC-----RDVAFTVGEGEDHDIPI 200 G+ T G+G + P G T +H G G+ FD + F +G+ E + Sbjct: 5 GVQVETISPGDGRTFPKRGQTCVVHYTGMLEDGKKFDSSRDRNKPFKFMLGKQE---VIR 61 Query: 201 GIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTLKSFE 251 G ++ + +M ++ L + P Y +G G P I P+A L+++V L E Sbjct: 62 GWEEGVAQMSVGQRAKLTISPDYAYGATGHPGI-IPPHATLVFDVELLKLE 111 >3UQI-A nrPDB Length = 108 Score = 166 bits (420), Expect = 2e-41, Method: Composition-based stats. Identities = 50/107 (46%), Positives = 66/107 (61%) Query: 32 GVLKIVKRVGNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVIKAWD 91 GV + G+ P G VHY G L++GK FDSS R +PF F++G+G+VI+ WD Sbjct: 2 GVQVVTLAAGDEATYPKAGQVAVVHYTGTLADGKVFDSSRTRGKPFRFTVGRGEVIRGWD 61 Query: 92 IGVATMKKGEICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELLDFK 138 GVA M G+ L+C P+YAYGS G IP NATL F++ELL + Sbjct: 62 EGVAQMSVGQRAKLVCSPDYAYGSRGHPGVIPPNATLTFDVELLRVE 108 Score = 129 bits (324), Expect = 3e-30, Method: Composition-based stats. Identities = 33/111 (29%), Positives = 49/111 (44%), Gaps = 10/111 (9%) Query: 147 GIIRRTKRKGEGYSNPNEGATVEIHLEGRC-GGRMFDC-----RDVAFTVGEGEDHDIPI 200 G+ T G+ + P G +H G G++FD + FTVG GE + Sbjct: 2 GVQVVTLAAGDEATYPKAGQVAVVHYTGTLADGKVFDSSRTRGKPFRFTVGRGE---VIR 58 Query: 201 GIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTLKSFE 251 G D+ + +M ++ L P Y +G G P I PNA L ++V L E Sbjct: 59 GWDEGVAQMSVGQRAKLVCSPDYAYGSRGHPGV-IPPNATLTFDVELLRVE 108 >5HUA-A nrPDB Length = 115 Score = 164 bits (416), Expect = 5e-41, Method: Composition-based stats. Identities = 50/114 (43%), Positives = 63/114 (55%) Query: 25 ITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKG 84 ++ + GV G+G+ P GD V +HY G L NG+KFDSS DR PF ++G G Sbjct: 2 MSETIEGGVKIDRLSPGDGKTFPKQGDLVTIHYTGTLENGQKFDSSVDRGSPFQCNIGVG 61 Query: 85 QVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELLDFK 138 QVIK WD G+ + GE L YAYG G IP NATL F++ELL Sbjct: 62 QVIKGWDAGIPKLSVGEKARLTIPGPYAYGPRGFPGLIPPNATLIFDVELLKVN 115 Score = 110 bits (276), Expect = 1e-24, Method: Composition-based stats. Identities = 32/112 (28%), Positives = 48/112 (42%), Gaps = 10/112 (8%) Query: 143 FEDGGIIRRTKRKGEGYSNPNEGATVEIHLEGRC-GGRMFDCR-----DVAFTVGEGEDH 196 +GG+ G+G + P +G V IH G G+ FD +G G+ Sbjct: 5 TIEGGVKIDRLSPGDGKTFPKQGDLVTIHYTGTLENGQKFDSSVDRGSPFQCNIGVGQ-- 62 Query: 197 DIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTLK 248 + G D + K+ E+ L + Y +G G P I PNA LI++V L Sbjct: 63 -VIKGWDAGIPKLSVGEKARLTIPGPYAYGPRGFPGL-IPPNATLIFDVELL 112 >2Y78-A nrPDB Length = 133 Score = 164 bits (416), Expect = 5e-41, Method: Composition-based stats. Identities = 54/121 (44%), Positives = 66/121 (54%), Gaps = 1/121 (0%) Query: 17 TVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEP 76 V + G+ G+G E G V VHY G L++G+KFDSS DRN+P Sbjct: 14 LVPRGSHMTVVTTESGLKYEDLTEGSGAEA-RAGQTVSVHYTGWLTDGQKFDSSKDRNDP 72 Query: 77 FVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELLD 136 F F LG G VIK WD GV MK G + L P+ YG+ G+ IP NATL FE+ELLD Sbjct: 73 FAFVLGGGMVIKGWDEGVQGMKVGGVRRLTIPPQLGYGARGAGGVIPPNATLVFEVELLD 132 Query: 137 F 137 Sbjct: 133 V 133 Score = 98.3 bits (243), Expect = 7e-21, Method: Composition-based stats. Identities = 31/115 (26%), Positives = 48/115 (41%), Gaps = 11/115 (9%) Query: 142 LFEDGGIIRRTKRKGEGYSNPNEGATVEIHLEGRC-GGRMFDCR-----DVAFTVGEGED 195 + + G+ +G G G TV +H G G+ FD AF +G G Sbjct: 24 VTTESGLKYEDLTEGSGAEA-RAGQTVSVHYTGWLTDGQKFDSSKDRNDPFAFVLGGG-- 80 Query: 196 HDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTLKSF 250 + G D+ ++ M+ L + P+ G+G G I PNA L++EV L Sbjct: 81 -MVIKGWDEGVQGMKVGGVRRLTIPPQLGYGARGAGGV-IPPNATLVFEVELLDV 133 >1YAT-A nrPDB Length = 113 Score = 164 bits (415), Expect = 6e-41, Method: Composition-based stats. Identities = 48/109 (44%), Positives = 60/109 (55%) Query: 30 DRGVLKIVKRVGNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVIKA 89 + V G+G P GD V +HY G L NG+KFDSS DR PF ++G GQVIK Sbjct: 5 EGNVKIDRISPGDGATFPKTGDLVTIHYTGTLENGQKFDSSVDRGSPFQCNIGVGQVIKG 64 Query: 90 WDIGVATMKKGEICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELLDFK 138 WD+G+ + GE L YAYG G IP N+TL F++ELL Sbjct: 65 WDVGIPKLSVGEKARLTIPGPYAYGPRGFPGLIPPNSTLVFDVELLKVN 113 Score = 108 bits (269), Expect = 6e-24, Method: Composition-based stats. Identities = 29/110 (26%), Positives = 46/110 (41%), Gaps = 10/110 (9%) Query: 145 DGGIIRRTKRKGEGYSNPNEGATVEIHLEGRC-GGRMFDCR-----DVAFTVGEGEDHDI 198 +G + G+G + P G V IH G G+ FD +G G+ + Sbjct: 5 EGNVKIDRISPGDGATFPKTGDLVTIHYTGTLENGQKFDSSVDRGSPFQCNIGVGQ---V 61 Query: 199 PIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTLK 248 G D + K+ E+ L + Y +G G P I PN+ L+++V L Sbjct: 62 IKGWDVGIPKLSVGEKARLTIPGPYAYGPRGFPGL-IPPNSTLVFDVELL 110 >2L2S-A nrPDB Length = 117 Score = 164 bits (414), Expect = 9e-41, Method: Composition-based stats. Identities = 54/116 (46%), Positives = 66/116 (56%), Gaps = 1/116 (0%) Query: 22 GEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSL 81 G + G+ G+G E G V VHY G L++G+KFDSS DRN+PF F L Sbjct: 3 GSMTVVTTESGLKYEDLTEGSGAEA-RAGQTVSVHYTGWLTDGQKFDSSKDRNDPFAFVL 61 Query: 82 GKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELLDF 137 G G VIK WD GV MK G + L P+ YG+ G+ IP NATL FE+ELLD Sbjct: 62 GGGMVIKGWDEGVQGMKVGGVRRLTIPPQLGYGARGAGGVIPPNATLVFEVELLDV 117 Score = 97.1 bits (240), Expect = 1e-20, Method: Composition-based stats. Identities = 31/115 (26%), Positives = 48/115 (41%), Gaps = 11/115 (9%) Query: 142 LFEDGGIIRRTKRKGEGYSNPNEGATVEIHLEGRC-GGRMFDCR-----DVAFTVGEGED 195 + + G+ +G G G TV +H G G+ FD AF +G G Sbjct: 8 VTTESGLKYEDLTEGSGAEA-RAGQTVSVHYTGWLTDGQKFDSSKDRNDPFAFVLGGG-- 64 Query: 196 HDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTLKSF 250 + G D+ ++ M+ L + P+ G+G G I PNA L++EV L Sbjct: 65 -MVIKGWDEGVQGMKVGGVRRLTIPPQLGYGARGAGGV-IPPNATLVFEVELLDV 117 >2LGO-A nrPDB Length = 130 Score = 159 bits (403), Expect = 2e-39, Method: Composition-based stats. Identities = 52/105 (49%), Positives = 62/105 (59%) Query: 33 VLKIVKRVGNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDI 92 + K V G+G P G KV VHY G+ +GK+FDSS R +PF F+LG G+VIK WD Sbjct: 26 LEKKVLTPGDGVTKPQAGKKVTVHYDGRFPDGKQFDSSRSRGKPFQFTLGAGEVIKGWDQ 85 Query: 93 GVATMKKGEICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELLDF 137 GVATM GE + AYG G P IP ATL FE+ELL Sbjct: 86 GVATMTLGEKALFTIPYQLAYGERGYPPVIPPKATLVFEVELLAV 130 Score = 119 bits (299), Expect = 2e-27, Method: Composition-based stats. Identities = 31/107 (28%), Positives = 51/107 (47%), Gaps = 10/107 (9%) Query: 150 RRTKRKGEGYSNPNEGATVEIHLEGRC-GGRMFDC-----RDVAFTVGEGEDHDIPIGID 203 ++ G+G + P G V +H +GR G+ FD + FT+G GE + G D Sbjct: 28 KKVLTPGDGVTKPQAGKKVTVHYDGRFPDGKQFDSSRSRGKPFQFTLGAGE---VIKGWD 84 Query: 204 KALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTLKSF 250 + + M E+ + + + +GE G P I P A L++EV L + Sbjct: 85 QGVATMTLGEKALFTIPYQLAYGERGYPPV-IPPKATLVFEVELLAV 130 >5T9S-F nrPDB Length = 108 Score = 159 bits (402), Expect = 3e-39, Method: Composition-based stats. Identities = 51/107 (47%), Positives = 64/107 (59%) Query: 32 GVLKIVKRVGNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVIKAWD 91 GV G+G P G VHY G L NGKKFDSS DRN+PF F +GK +VIK ++ Sbjct: 2 GVEIETISPGDGRTFPKKGQTCVVHYTGMLQNGKKFDSSRDRNKPFKFRIGKQEVIKGFE 61 Query: 92 IGVATMKKGEICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELLDFK 138 G A M G+ L C P+ AYG+ G IP NATL F++ELL+ + Sbjct: 62 EGAAQMSLGQRAKLTCTPDVAYGATGHPGVIPPNATLIFDVELLNLE 108 Score = 105 bits (261), Expect = 6e-23, Method: Composition-based stats. Identities = 31/111 (27%), Positives = 50/111 (45%), Gaps = 10/111 (9%) Query: 147 GIIRRTKRKGEGYSNPNEGATVEIHLEGRC-GGRMFDC-----RDVAFTVGEGEDHDIPI 200 G+ T G+G + P +G T +H G G+ FD + F +G+ E + Sbjct: 2 GVEIETISPGDGRTFPKKGQTCVVHYTGMLQNGKKFDSSRDRNKPFKFRIGKQE---VIK 58 Query: 201 GIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTLKSFE 251 G ++ +M ++ L P +G G P I PNA LI++V L + E Sbjct: 59 GFEEGAAQMSLGQRAKLTCTPDVAYGATGHPGV-IPPNATLIFDVELLNLE 108 >5JHE-A nrPDB Length = 397 Score = 159 bits (402), Expect = 3e-39, Method: Composition-based stats. Identities = 39/156 (25%), Positives = 69/156 (44%), Gaps = 7/156 (4%) Query: 265 LEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYGLSEKESKASESF---LLAAFL 321 LE A I+KE GT+ FK Y A +Y K ++++ + + + + F + +L Sbjct: 241 LEAANIIKESGTLLFKKKDYSNAFFKYRKSLNYINEYMPEPDVDKERNIQFINLKMKIYL 300 Query: 322 NLAMCYLKLREYTKAVECCDKALGLDS----ANEKGLYRRGEAQLLMNEFESAKGDFEKV 377 NL++ L Y A+ L +D+ K YRRG + L + A D+ Sbjct: 301 NLSLVLFNLERYDDAIMYATYLLEMDNVPNRDQAKAYYRRGNSYLKKKRLDEALQDYIFC 360 Query: 378 LEVNPQNKAARLQISMCQKKAKEHNERDRRIYANMF 413 E NP ++ +I + +E+ E+ R+ + F Sbjct: 361 KEKNPDDEVIEQRIEYVNRLIEENKEKTRKNISKFF 396 >4GIV-A nrPDB Length = 209 Score = 157 bits (397), Expect = 1e-38, Method: Composition-based stats. Identities = 55/136 (40%), Positives = 72/136 (52%), Gaps = 1/136 (0%) Query: 2 TTDEGAKNNEESPTATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGKL 61 T ++ + + A + G + G+ G+G E G V VHY G L Sbjct: 75 TPEDLDMEDNDIIEAHREQIGGSTVVTTESGLKYEDLTEGSGAEA-RAGQTVSVHYTGWL 133 Query: 62 SNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLPK 121 ++G+KF SS DRN+PF F LG G VIK WD GV MK G + L P+ YG+ G+ Sbjct: 134 TDGQKFGSSKDRNDPFAFVLGGGMVIKGWDEGVQGMKVGGVRRLTIPPQLGYGARGAGGV 193 Query: 122 IPSNATLFFEIELLDF 137 IP NATL FE+ELLD Sbjct: 194 IPPNATLVFEVELLDV 209 Score = 90.6 bits (223), Expect = 1e-18, Method: Composition-based stats. Identities = 30/115 (26%), Positives = 47/115 (40%), Gaps = 11/115 (9%) Query: 142 LFEDGGIIRRTKRKGEGYSNPNEGATVEIHLEGRC-GGRMFDCR-----DVAFTVGEGED 195 + + G+ +G G G TV +H G G+ F AF +G G Sbjct: 100 VTTESGLKYEDLTEGSGAEA-RAGQTVSVHYTGWLTDGQKFGSSKDRNDPFAFVLGGG-- 156 Query: 196 HDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTLKSF 250 + G D+ ++ M+ L + P+ G+G G I PNA L++EV L Sbjct: 157 -MVIKGWDEGVQGMKVGGVRRLTIPPQLGYGARGAGGV-IPPNATLVFEVELLDV 209 >5L1D-B nrPDB Length = 158 Score = 157 bits (396), Expect = 1e-38, Method: Composition-based stats. Identities = 51/107 (47%), Positives = 64/107 (59%) Query: 32 GVLKIVKRVGNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVIKAWD 91 GV G+G P G VHY G L NGKKFDSS DRN+PF F +GK +VIK ++ Sbjct: 52 GVEIETISPGDGRTFPKKGQTCVVHYTGMLQNGKKFDSSRDRNKPFKFRIGKQEVIKGFE 111 Query: 92 IGVATMKKGEICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELLDFK 138 G A M G+ L C P+ AYG+ G IP NATL F++ELL+ + Sbjct: 112 EGAAQMSLGQRAKLTCTPDVAYGATGHPGVIPPNATLIFDVELLNLE 158 Score = 103 bits (256), Expect = 2e-22, Method: Composition-based stats. Identities = 31/111 (27%), Positives = 50/111 (45%), Gaps = 10/111 (9%) Query: 147 GIIRRTKRKGEGYSNPNEGATVEIHLEGRC-GGRMFDC-----RDVAFTVGEGEDHDIPI 200 G+ T G+G + P +G T +H G G+ FD + F +G+ E + Sbjct: 52 GVEIETISPGDGRTFPKKGQTCVVHYTGMLQNGKKFDSSRDRNKPFKFRIGKQE---VIK 108 Query: 201 GIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTLKSFE 251 G ++ +M ++ L P +G G P I PNA LI++V L + E Sbjct: 109 GFEEGAAQMSLGQRAKLTCTPDVAYGATGHPGV-IPPNATLIFDVELLNLE 158 >3IHZ-A nrPDB Length = 126 Score = 156 bits (394), Expect = 2e-38, Method: Composition-based stats. Identities = 59/122 (48%), Positives = 75/122 (61%), Gaps = 3/122 (2%) Query: 20 EQGEDITSKKDRGVLKIVKRVGNG--EETPMIGDKVYVHYKGKLSN-GKKFDSSHDRNEP 76 E E + +D GV+K + R G G E P G++V VHY GKL + GK FDSS +RN P Sbjct: 4 ETLEQVHLTEDGGVVKTILRKGEGGEENAPKKGNEVTVHYVGKLESSGKVFDSSRERNVP 63 Query: 77 FVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELLD 136 F F LG+G+VIK WDI VA+M K E C + +Y YG G IP N+ L FEIEL+ Sbjct: 64 FKFHLGQGEVIKGWDICVASMTKNEKCSVRLDSKYGYGEEGCGESIPGNSVLIFEIELIS 123 Query: 137 FK 138 F+ Sbjct: 124 FR 125 Score = 129 bits (323), Expect = 4e-30, Method: Composition-based stats. Identities = 41/121 (33%), Positives = 64/121 (52%), Gaps = 13/121 (10%) Query: 141 DLFEDGGIIRRTKRKGEG--YSNPNEGATVEIHLEGRC--GGRMFDCR-----DVAFTVG 191 L EDGG+++ RKGEG + P +G V +H G+ G++FD F +G Sbjct: 10 HLTEDGGVVKTILRKGEGGEENAPKKGNEVTVHYVGKLESSGKVFDSSRERNVPFKFHLG 69 Query: 192 EGEDHDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTLKSFE 251 +GE + G D + M + E+C + L +YG+GE G + I N+ LI+E+ L SF Sbjct: 70 QGE---VIKGWDICVASMTKNEKCSVRLDSKYGYGEEGCGE-SIPGNSVLIFEIELISFR 125 Query: 252 K 252 + Sbjct: 126 E 126 >4NNR-A nrPDB Length = 142 Score = 154 bits (390), Expect = 5e-38, Method: Composition-based stats. Identities = 52/107 (48%), Positives = 66/107 (61%), Gaps = 3/107 (2%) Query: 32 GVLKIVKRVGNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVIKAWD 91 GV K V + GD +++HY GKL +G +FDSS +N+PFVFSLG GQVIK WD Sbjct: 34 GVKKRVD---HCPIKSRKGDVLHMHYTGKLEDGTEFDSSLPQNQPFVFSLGTGQVIKGWD 90 Query: 92 IGVATMKKGEICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELLDFK 138 G+ M +GE L+ E YG G+ PKIP ATL FE+ELL + Sbjct: 91 QGLLGMCEGEKRKLVIPSELGYGERGAPPKIPGGATLVFEVELLKIE 137 Score = 93.3 bits (230), Expect = 2e-19, Method: Composition-based stats. Identities = 28/102 (27%), Positives = 43/102 (42%), Gaps = 10/102 (9%) Query: 161 NPNEGATVEIHLEGRC-GGRMFDCR-----DVAFTVGEGEDHDIPIGIDKALEKMQREEQ 214 +G + +H G+ G FD F++G G+ + G D+ L M E+ Sbjct: 45 KSRKGDVLHMHYTGKLEDGTEFDSSLPQNQPFVFSLGTGQ---VIKGWDQGLLGMCEGEK 101 Query: 215 CILYLGPRYGFGEAGKPKFGIEPNAELIYEVTLKSFEKAKES 256 L + G+GE G P I A L++EV L E+ E Sbjct: 102 RKLVIPSELGYGERGAPP-KIPGGATLVFEVELLKIERRTEL 142 >2MPH-A nrPDB Length = 224 Score = 153 bits (387), Expect = 1e-37, Method: Composition-based stats. Identities = 52/142 (36%), Positives = 72/142 (50%), Gaps = 11/142 (7%) Query: 5 EGAKNNEESPTATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGKLSNG 64 + K NE+ P T +E+ D K K V + G+ P GD V+ Y G L +G Sbjct: 86 KNVKLNEDKPKETKSEETLDEGPPK---YTKSVLKKGDKTNFPKKGDVVHCWYTGTLQDG 142 Query: 65 KKFDSSHDRN-------EPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAG 117 FD++ + +P F +G G+VI+ WD + TM KGE L +PE+AYG G Sbjct: 143 TVFDTNIQTSAKKKKNAKPLSFKVGVGKVIRGWDEALLTMSKGEKARLEIEPEWAYGKKG 202 Query: 118 SLP-KIPSNATLFFEIELLDFK 138 KIP NA L FE+EL+D Sbjct: 203 QPDAKIPPNAKLTFEVELVDID 224 Score = 111 bits (278), Expect = 5e-25, Method: Composition-based stats. Identities = 32/116 (27%), Positives = 54/116 (46%), Gaps = 16/116 (13%) Query: 149 IRRTKRKGEGYSNPNEGATVEIHLEGRC-GGRMFD------------CRDVAFTVGEGED 195 + +KG+ + P +G V G G +FD + ++F VG G+ Sbjct: 112 TKSVLKKGDKTNFPKKGDVVHCWYTGTLQDGTVFDTNIQTSAKKKKNAKPLSFKVGVGK- 170 Query: 196 HDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTLKSFE 251 + G D+AL M + E+ L + P + +G+ G+P I PNA+L +EV L + Sbjct: 171 --VIRGWDEALLTMSKGEKARLEIEPEWAYGKKGQPDAKIPPNAKLTFEVELVDID 224 >4QT3-A nrPDB Length = 134 Score = 151 bits (381), Expect = 6e-37, Method: Composition-based stats. Identities = 56/122 (45%), Positives = 75/122 (61%), Gaps = 3/122 (2%) Query: 20 EQGEDITSKKDRGVLKIVKRVGNG--EETPMIGDKVYVHYKGKLSN-GKKFDSSHDRNEP 76 ++ E + D GV+K + + G+ E P G++V VHY GKL + GK FDSS DRN P Sbjct: 1 QEFEKVELTADGGVIKTILKKGDEGEENIPKKGNEVTVHYVGKLESTGKVFDSSFDRNVP 60 Query: 77 FVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELLD 136 F F L +G+VIK WDI V++M+K E C + + Y YG G IP N+ L FEIELL Sbjct: 61 FKFHLEQGEVIKGWDICVSSMRKNEKCLVRIESMYGYGDEGCGESIPGNSVLLFEIELLS 120 Query: 137 FK 138 F+ Sbjct: 121 FR 122 Score = 130 bits (327), Expect = 1e-30, Method: Composition-based stats. Identities = 39/129 (30%), Positives = 71/129 (55%), Gaps = 9/129 (6%) Query: 136 DFKGEDLFEDGGIIRRTKRKGE-GYSN-PNEGATVEIHLEGRC--GGRMFDC---RDVAF 188 +F+ +L DGG+I+ +KG+ G N P +G V +H G+ G++FD R+V F Sbjct: 2 EFEKVELTADGGVIKTILKKGDEGEENIPKKGNEVTVHYVGKLESTGKVFDSSFDRNVPF 61 Query: 189 TVGEGEDHDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTLK 248 E ++ G D + M++ E+C++ + YG+G+ G + I N+ L++E+ L Sbjct: 62 KF-HLEQGEVIKGWDICVSSMRKNEKCLVRIESMYGYGDEGCGE-SIPGNSVLLFEIELL 119 Query: 249 SFEKAKESW 257 SF + +E+ Sbjct: 120 SFRELEETS 128 >2PBC-A nrPDB Length = 102 Score = 144 bits (364), Expect = 6e-35, Method: Composition-based stats. Identities = 48/95 (50%), Positives = 61/95 (64%) Query: 44 EETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEIC 103 GD +++HY GKL +G +FDSS +N+PFVFSLG GQVIK WD G+ M +GE Sbjct: 3 PIKSRKGDVLHMHYTGKLEDGTEFDSSLPQNQPFVFSLGTGQVIKGWDQGLLGMCEGEKR 62 Query: 104 HLLCKPEYAYGSAGSLPKIPSNATLFFEIELLDFK 138 L+ E YG G+ PKIP ATL FE+ELL + Sbjct: 63 KLVIPSELGYGERGAPPKIPGGATLVFEVELLKIE 97 Score = 89.4 bits (220), Expect = 3e-18, Method: Composition-based stats. Identities = 28/102 (27%), Positives = 43/102 (42%), Gaps = 10/102 (9%) Query: 161 NPNEGATVEIHLEGRC-GGRMFDCR-----DVAFTVGEGEDHDIPIGIDKALEKMQREEQ 214 +G + +H G+ G FD F++G G+ + G D+ L M E+ Sbjct: 5 KSRKGDVLHMHYTGKLEDGTEFDSSLPQNQPFVFSLGTGQ---VIKGWDQGLLGMCEGEK 61 Query: 215 CILYLGPRYGFGEAGKPKFGIEPNAELIYEVTLKSFEKAKES 256 L + G+GE G P I A L++EV L E+ E Sbjct: 62 RKLVIPSELGYGERGAPP-KIPGGATLVFEVELLKIERRTEL 102 >5HW8-A nrPDB Length = 122 Score = 143 bits (360), Expect = 2e-34, Method: Composition-based stats. Identities = 46/116 (39%), Positives = 59/116 (50%), Gaps = 11/116 (9%) Query: 36 IVKRVGNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIG-- 93 + + G+ GD V +HY GKL+NGK+FDSS R +PF ++G GQVIK WDI Sbjct: 7 EIVQEGDNTTFAKPGDTVTIHYDGKLTNGKEFDSSRKRGKPFTCTVGVGQVIKGWDISLT 66 Query: 94 ---------VATMKKGEICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELLDFKGE 140 + + KG L P AYG G I N TL FE+ELL G+ Sbjct: 67 NNYGKGGANLPKISKGTKAILTIPPNLAYGPRGIPGIIGPNETLVFEVELLGVNGQ 122 Score = 84.4 bits (207), Expect = 9e-17, Method: Composition-based stats. Identities = 31/119 (26%), Positives = 49/119 (41%), Gaps = 21/119 (17%) Query: 151 RTKRKGEGYSNPNEGATVEIHLEGRC-GGRMFDC-----RDVAFTVGEGEDHDIPIGIDK 204 ++G+ + G TV IH +G+ G+ FD + TVG G+ + G D Sbjct: 7 EIVQEGDNTTFAKPGDTVTIHYDGKLTNGKEFDSSRKRGKPFTCTVGVGQ---VIKGWDI 63 Query: 205 AL-----------EKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTLKSFEK 252 +L K+ + + IL + P +G G P I PN L++EV L Sbjct: 64 SLTNNYGKGGANLPKISKGTKAILTIPPNLAYGPRGIPGI-IGPNETLVFEVELLGVNG 121 >5B8I-C nrPDB Length = 130 Score = 142 bits (359), Expect = 2e-34, Method: Composition-based stats. Identities = 46/123 (37%), Positives = 66/123 (53%), Gaps = 10/123 (8%) Query: 27 SKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGKLSN---------GKKFDSSHDRNEPF 77 +K GV K + + GNG + P+ GD + ++Y+G L + G+KFDS+ +R E F Sbjct: 7 FEKGSGVTKKILKEGNGVDKPVKGDDIVMNYRGCLYDSSKPSEHFMGRKFDSTEERGE-F 65 Query: 78 VFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELLDF 137 +G G VI+ WD V M GE L +YAYG+ G IP +ATL FE+EL Sbjct: 66 KTKIGIGVVIRGWDEAVLQMSLGEKSILTITDDYAYGARGFPGLIPPHATLVFEVELKGI 125 Query: 138 KGE 140 + Sbjct: 126 NSK 128 Score = 102 bits (255), Expect = 3e-22, Method: Composition-based stats. Identities = 31/125 (24%), Positives = 53/125 (42%), Gaps = 14/125 (11%) Query: 137 FKGEDLFEDGGIIRRTKRKGEGYSNPNEGATVEIHLEGRC----------GGRMFDCRDV 186 + + G+ ++ ++G G P +G + ++ G GR FD + Sbjct: 2 WSHPQFEKGSGVTKKILKEGNGVDKPVKGDDIVMNYRGCLYDSSKPSEHFMGRKFDSTEE 61 Query: 187 A--FTVGEGEDHDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYE 244 F G + G D+A+ +M E+ IL + Y +G G P I P+A L++E Sbjct: 62 RGEFKTKIG-IGVVIRGWDEAVLQMSLGEKSILTITDDYAYGARGFPGL-IPPHATLVFE 119 Query: 245 VTLKS 249 V LK Sbjct: 120 VELKG 124 >3B7X-A nrPDB Length = 134 Score = 139 bits (351), Expect = 2e-33, Method: Composition-based stats. Identities = 49/130 (37%), Positives = 73/130 (56%), Gaps = 4/130 (3%) Query: 11 EESPTATVAEQ--GEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGKLSN-GKKF 67 +++P ++ E+ + DRGVLK V R G G+ V V Y G L + + F Sbjct: 4 DDAPGQSLYERLSQRMLDISGDRGVLKDVIREGAGDLVAPDAS-VLVKYSGYLEHMDRPF 62 Query: 68 DSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLPKIPSNAT 127 DS++ R P + LG+ + ++G+ +M++GE+ L KP YAYG+ G P IP N T Sbjct: 63 DSNYFRKTPRLMKLGEDITLWGMELGLLSMRRGELARFLFKPNYAYGTLGCPPLIPPNTT 122 Query: 128 LFFEIELLDF 137 + FEIELLDF Sbjct: 123 VLFEIELLDF 132 Score = 87.5 bits (215), Expect = 1e-17, Method: Composition-based stats. Identities = 35/124 (28%), Positives = 54/124 (43%), Gaps = 10/124 (8%) Query: 133 ELLDFKGEDLFEDGGIIRRTKRKGEGY-SNPNEGATVEIHLEGRCG--GRMFDCRDVAFT 189 E L + D+ D G+++ R+G G P+ A+V + G R FD T Sbjct: 13 ERLSQRMLDISGDRGVLKDVIREGAGDLVAPD--ASVLVKYSGYLEHMDRPFDSNYFRKT 70 Query: 190 ---VGEGEDHDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVT 246 + GED + G++ L M+R E P Y +G G P I PN +++E+ Sbjct: 71 PRLMKLGEDITL-WGMELGLLSMRRGELARFLFKPNYAYGTLGCPPL-IPPNTTVLFEIE 128 Query: 247 LKSF 250 L F Sbjct: 129 LLDF 132 >4JA9-A nrPDB Length = 488 Score = 138 bits (347), Expect = 5e-33, Method: Composition-based stats. Identities = 39/153 (25%), Positives = 68/153 (44%), Gaps = 16/153 (10%) Query: 256 SWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYGLSEKESKASESF 315 E + L++A +K + YFK Y A+ Y + + E S + Sbjct: 5 RDEPPAEGTLKRAEELKTQANDYFKAKDYENAIKFYSQAI------------ELNPSNAI 52 Query: 316 LLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFE 375 + N ++ YL+ Y A+ +A+ LD KG YRR + + + +F +A D+E Sbjct: 53 Y---YGNRSLAYLRTECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYE 109 Query: 376 KVLEVNPQNKAARLQISMCQKKAKEHNERDRRI 408 V++V P +K A+++ C K K +R I Sbjct: 110 TVVKVKPNDKDAKMKYQECSKIVK-QKAFERAI 141 >4I2W-A nrPDB Length = 961 Score = 137 bits (346), Expect = 7e-33, Method: Composition-based stats. Identities = 42/173 (24%), Positives = 75/173 (43%), Gaps = 15/173 (8%) Query: 264 KLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYGLSEKESKASESFLLAAFLNL 323 +++ A ++++G K Y++A Y + + L+ E KA L + N Sbjct: 4 RVQTAEEIRDEGNAAVKDQDYIKADELYTEALQ-------LTTDEDKALRPVL---YRNR 53 Query: 324 AMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEVNPQ 383 AM LK ++ A C KAL D A+ K L+RR A+ + A D ++ L ++P Sbjct: 54 AMARLKRDDFEGAQSDCTKALEFDGADVKALFRRSLAREQLGNVGPAFQDAKEALRLSPN 113 Query: 384 NKAARLQISMCQKKAKEHNE--RDRRIYANMFKKFAEQDAKEEANKAMGKKTS 434 +K + + Q+ K +N+ + AN + + EA K T+ Sbjct: 114 DKGI---VEVLQRLVKANNDKIKQTTSLANKVTDMEKLAFRGEAKDTEQKMTA 163 >6FO1-G nrPDB Length = 665 Score = 137 bits (345), Expect = 1e-32, Method: Composition-based stats. Identities = 47/153 (30%), Positives = 80/153 (52%), Gaps = 17/153 (11%) Query: 244 EVTLKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYG 303 ++ +KS E E +++ ++ +QA K++G +FK GKY +A+ Y + G Sbjct: 260 DIVIKSTEG--ERKQIEAQQNKQQAISEKDRGNGFFKEGKYERAIECYTR---------G 308 Query: 304 LSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLL 363 ++ + A N AM YLK+++Y +A + C +A+ LD + K RRG A+ Sbjct: 309 IAADGANALLP------ANRAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTARTF 362 Query: 364 MNEFESAKGDFEKVLEVNPQNKAARLQISMCQK 396 + + AK DFE VL + P NK A ++S +K Sbjct: 363 LGKLNEAKQDFETVLLLEPGNKQAVTELSKIKK 395 Score = 102 bits (254), Expect = 3e-22, Method: Composition-based stats. Identities = 47/188 (25%), Positives = 86/188 (45%), Gaps = 19/188 (10%) Query: 266 EQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYGLSEKESKASESFLLAAFLNLAM 325 ++A ++KEKG YFK GKY +A+ Y K G+ N A Sbjct: 131 QKALVLKEKGNKYFKQGKYDEAIDCYTK---------GMDADPYNPVLP------TNRAS 175 Query: 326 CYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEVNPQNK 385 Y +L+++ A C+ A+ L+ + K RRG A+ + + E AK D+E+VLE+ P N Sbjct: 176 AYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNF 235 Query: 386 AARLQISMCQK-KAKEHNERDRRI---YANMFKKFAEQDAKEEANKAMGKKTSEGVTNEK 441 A ++ + A + N + + + + +A++ +A+ +K ++ Sbjct: 236 EATNELRKISQALASKENSYPKEADIVIKSTEGERKQIEAQQNKQQAISEKDRGNGFFKE 295 Query: 442 GTDSQAME 449 G +A+E Sbjct: 296 GKYERAIE 303 >1JVW-A nrPDB Length = 167 Score = 136 bits (343), Expect = 2e-32, Method: Composition-based stats. Identities = 42/120 (35%), Positives = 60/120 (50%), Gaps = 8/120 (6%) Query: 28 KKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVI 87 K G++ G+G+ P I DK VHY G+L +G FDSS +R +P F +VI Sbjct: 34 KLPSGLVFQRIARGSGKRAPAIDDKCEVHYTGRLRDGTVFDSSRERGKPTTFR--PNEVI 91 Query: 88 KAWDIGVATMKKGEICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELLDFKGEDLFEDGG 147 K W + M++G+ L + AYG G IP + L F++EL+ K DGG Sbjct: 92 KGWTEALQLMREGDRWRLFIPYDLAYGVTGGGGMIPPYSPLEFDVELISIK------DGG 145 Score = 80.5 bits (197), Expect = 1e-15, Method: Composition-based stats. Identities = 30/131 (22%), Positives = 53/131 (40%), Gaps = 4/131 (3%) Query: 146 GGIIRRTKRKGEGYSNPNEGATVEIHLEGRC-GGRMFDCRDVAFTVGEGEDHDIPIGIDK 204 G + +R +G G P E+H GR G +FD +++ G + Sbjct: 38 GLVFQRI-ARGSGKRAPAIDDKCEVHYTGRLRDGTVFDSSRERGKPTTFRPNEVIKGWTE 96 Query: 205 ALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTLKSFEK-AKESWEMDTKE 263 AL+ M+ ++ L++ +G G I P + L ++V L S + K + E Sbjct: 97 ALQLMREGDRWRLFIPYDLAYGVTGGGGM-IPPYSPLEFDVELISIKDGGKGRTAEEVDE 155 Query: 264 KLEQAAIVKEK 274 L +A +E Sbjct: 156 ILRKAEEDRED 166 >5D75-A nrPDB Length = 124 Score = 134 bits (337), Expect = 9e-32, Method: Composition-based stats. Identities = 44/116 (37%), Positives = 60/116 (51%), Gaps = 8/116 (6%) Query: 31 RGVLKIVKRVGNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRN-------EPFVFSLGK 83 K V + G+ P GD V+ Y G L +G FD++ + +P F +G Sbjct: 1 PKYTKSVLKKGDKTNFPKKGDVVHCWYTGTLQDGTVFDTNIQTSAKKKKNAKPLSFKVGV 60 Query: 84 GQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLP-KIPSNATLFFEIELLDFK 138 G+VI+ WD + TM KGE L +PE+AYG G KIP NA L FE+EL+D Sbjct: 61 GKVIRGWDEALLTMSKGEKARLEIEPEWAYGKKGQPDAKIPPNAKLTFEVELVDID 116 Score = 112 bits (280), Expect = 3e-25, Method: Composition-based stats. Identities = 32/116 (27%), Positives = 54/116 (46%), Gaps = 16/116 (13%) Query: 149 IRRTKRKGEGYSNPNEGATVEIHLEGRC-GGRMFD------------CRDVAFTVGEGED 195 + +KG+ + P +G V G G +FD + ++F VG G+ Sbjct: 4 TKSVLKKGDKTNFPKKGDVVHCWYTGTLQDGTVFDTNIQTSAKKKKNAKPLSFKVGVGK- 62 Query: 196 HDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTLKSFE 251 + G D+AL M + E+ L + P + +G+ G+P I PNA+L +EV L + Sbjct: 63 --VIRGWDEALLTMSKGEKARLEIEPEWAYGKKGQPDAKIPPNAKLTFEVELVDID 116 >5JJT-A nrPDB Length = 479 Score = 133 bits (334), Expect = 2e-31, Method: Composition-based stats. Identities = 41/141 (29%), Positives = 66/141 (46%), Gaps = 15/141 (10%) Query: 265 LEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYGLSEKESKASESFLLAAFLNLA 324 + +A K + FKG KY A+ Y K + E ++ + A N A Sbjct: 6 VSRAEEFKSQANEAFKGHKYSSAIDLYTKAI------------ELNSNNAVYWA---NRA 50 Query: 325 MCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEVNPQN 384 + KL EY A++ KA+ +DS KG YRRG A L M +F+ A DF++V ++P + Sbjct: 51 FAHTKLEEYGSAIQDASKAIEVDSRYSKGYYRRGAAYLAMGKFKDALKDFQQVKRLSPND 110 Query: 385 KAARLQISMCQKKAKEHNERD 405 A ++ C+K + + Sbjct: 111 PDATRKLKECEKAVMKLKFEE 131 >2D9F-A nrPDB Length = 135 Score = 131 bits (328), Expect = 9e-31, Method: Composition-based stats. Identities = 33/121 (27%), Positives = 57/121 (47%), Gaps = 6/121 (4%) Query: 141 DLFEDGGIIRRTKRKGE-GYSNPNEGATVEIHLEGRC--GGRMFDCRDVAFTVGEGEDHD 197 D+ +G + ++T G G S P +G V +HL+ G R+ + ++ FT+G D D Sbjct: 12 DILGNGLLRKKTLVPGPPGSSRPVKGQVVTVHLQTSLENGTRVQEEPELVFTLG---DCD 68 Query: 198 IPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTLKSFEKAKESW 257 + +D ++ M E ++ +Y +G G I P+A L EVTLK+ + Sbjct: 69 VIQALDLSVPLMDVGETAMVTADSKYCYGPQGSRSPYIPPHAALCLEVTLKTAVDRPDLE 128 Query: 258 E 258 Sbjct: 129 M 129 Score = 108 bits (270), Expect = 4e-24, Method: Composition-based stats. Identities = 38/107 (35%), Positives = 49/107 (45%), Gaps = 8/107 (7%) Query: 43 GEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEP-FVFSLGKGQVIKAWDIGVATMKKGE 101 G P+ G V VH + L NG + + EP VF+LG VI+A D+ V M GE Sbjct: 30 GSSRPVKGQVVTVHLQTSLENGTRV-----QEEPELVFTLGDCDVIQALDLSVPLMDVGE 84 Query: 102 ICHLLCKPEYAYGSAGS-LPKIPSNATLFFEIEL-LDFKGEDLFEDG 146 + +Y YG GS P IP +A L E+ L DL G Sbjct: 85 TAMVTADSKYCYGPQGSRSPYIPPHAALCLEVTLKTAVDRPDLEMSG 131 >5I7Q-A nrPDB Length = 162 Score = 131 bits (328), Expect = 1e-30, Method: Composition-based stats. Identities = 54/156 (34%), Positives = 72/156 (46%), Gaps = 13/156 (8%) Query: 32 GVLKIVKRVGNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVIKAWD 91 GV G+G P G VHY G L +GKKFDSS DRN+PF F LGK +VI+ W+ Sbjct: 1 GVQVETISPGDGRTFPKRGQTAVVHYTGMLEDGKKFDSSRDRNKPFKFMLGKQEVIRGWE 60 Query: 92 IGVATMKKGEICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELLDFKGEDLFEDGGIIRR 151 GVA M G+ L P+YAYG S I + F +D ++ G I+ Sbjct: 61 EGVAQMSVGQRAKLTISPDYAYGVP-SPDLIQYFSRREF----MDAGEPEI---GAIMLF 112 Query: 152 TKRKG---EGYSNPNEGATVEIHLEGRCGGR--MFD 182 T G G G ++ + G+ +FD Sbjct: 113 TAMDGSEMPGVIREINGDSITVDFNHPLAGQTLVFD 148 Score = 88.3 bits (217), Expect = 6e-18, Method: Composition-based stats. Identities = 21/86 (24%), Positives = 38/86 (44%), Gaps = 9/86 (10%) Query: 147 GIIRRTKRKGEGYSNPNEGATVEIHLEGRC-GGRMFDC-----RDVAFTVGEGEDHDIPI 200 G+ T G+G + P G T +H G G+ FD + F +G+ E + Sbjct: 1 GVQVETISPGDGRTFPKRGQTAVVHYTGMLEDGKKFDSSRDRNKPFKFMLGKQE---VIR 57 Query: 201 GIDKALEKMQREEQCILYLGPRYGFG 226 G ++ + +M ++ L + P Y +G Sbjct: 58 GWEEGVAQMSVGQRAKLTISPDYAYG 83 >2VCD-A nrPDB Length = 137 Score = 130 bits (326), Expect = 1e-30, Method: Composition-based stats. Identities = 40/138 (28%), Positives = 52/138 (37%), Gaps = 6/138 (4%) Query: 3 TDEGAKNNEESPTATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGKLS 62 DE E T + G + G+ V GNG P D V V Y G+L Sbjct: 5 ADENKVKGEAFLTENKNKPGVVVLPS---GLQYKVINSGNGV-KPGKSDTVTVEYTGRLI 60 Query: 63 NGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLPKI 122 +G FDS+ +P F + QVI W + M G + AYG I Sbjct: 61 DGTVFDSTEKTGKPATFQV--SQVIPGWTEALQLMPAGSTWEIYVPSGLAYGPRSVGGPI 118 Query: 123 PSNATLFFEIELLDFKGE 140 N TL F+I L+ K Sbjct: 119 GPNETLIFKIHLISVKKS 136 Score = 72.1 bits (175), Expect = 5e-13, Method: Composition-based stats. Identities = 25/109 (22%), Positives = 43/109 (39%), Gaps = 3/109 (2%) Query: 147 GIIRRTKRKGEGYSNPNEGATVEIHLEGRC-GGRMFDCRDVAFTVGEGEDHDIPIGIDKA 205 G+ + G G P + TV + GR G +FD + + + G +A Sbjct: 31 GLQYKVINSGNGV-KPGKSDTVTVEYTGRLIDGTVFDSTEKTGKPATFQVSQVIPGWTEA 89 Query: 206 LEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTLKSFEKAK 254 L+ M +Y+ +G I PN LI+++ L S +K+ Sbjct: 90 LQLMPAGSTWEIYVPSGLAYGPRSVGGP-IGPNETLIFKIHLISVKKSS 137 >5I7P-A nrPDB Length = 161 Score = 129 bits (324), Expect = 3e-30, Method: Composition-based stats. Identities = 41/83 (49%), Positives = 49/83 (59%) Query: 32 GVLKIVKRVGNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVIKAWD 91 GV G+G P G VHY G L +GKKFDSS DRN+PF F LGK +VI+ W+ Sbjct: 1 GVQVETISPGDGRTFPKRGQTAVVHYTGMLEDGKKFDSSRDRNKPFKFMLGKQEVIRGWE 60 Query: 92 IGVATMKKGEICHLLCKPEYAYG 114 GVA M G+ L P+YAYG Sbjct: 61 EGVAQMSVGQRAKLTISPDYAYG 83 Score = 87.5 bits (215), Expect = 1e-17, Method: Composition-based stats. Identities = 21/87 (24%), Positives = 39/87 (44%), Gaps = 9/87 (10%) Query: 147 GIIRRTKRKGEGYSNPNEGATVEIHLEGRC-GGRMFDC-----RDVAFTVGEGEDHDIPI 200 G+ T G+G + P G T +H G G+ FD + F +G+ E + Sbjct: 1 GVQVETISPGDGRTFPKRGQTAVVHYTGMLEDGKKFDSSRDRNKPFKFMLGKQE---VIR 57 Query: 201 GIDKALEKMQREEQCILYLGPRYGFGE 227 G ++ + +M ++ L + P Y +G+ Sbjct: 58 GWEEGVAQMSVGQRAKLTISPDYAYGQ 84 >1Y0O-A nrPDB Length = 129 Score = 128 bits (321), Expect = 5e-30, Method: Composition-based stats. Identities = 45/110 (40%), Positives = 57/110 (51%), Gaps = 12/110 (10%) Query: 38 KRVGNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDI----- 92 K VG G E + G + HY GKL NGK FDSS++R +P F +G G+VIK WD Sbjct: 19 KVVGYGPEA-VKGQLIKAHYVGKLENGKVFDSSYNRGKPLTFRIGVGEVIKGWDQGILGS 77 Query: 93 -GVATMKKGEICHLLCKPEYAYGSAGSLPK-----IPSNATLFFEIELLD 136 G+ M G L PE AYG G+ K IP + L F+IE + Sbjct: 78 DGIPPMLTGGKRTLRIPPELAYGDRGAGCKGGSCLIPPASVLLFDIEYIG 127 Score = 72.5 bits (176), Expect = 3e-13, Method: Composition-based stats. Identities = 24/113 (21%), Positives = 45/113 (39%), Gaps = 20/113 (17%) Query: 153 KRKGEGYSNPNEGATVEIHLEGRC-GGRMFDC-----RDVAFTVGEGEDHDIPIGIDKAL 206 K G G +G ++ H G+ G++FD + + F +G GE + G D+ + Sbjct: 19 KVVGYGPEA-VKGQLIKAHYVGKLENGKVFDSSYNRGKPLTFRIGVGE---VIKGWDQGI 74 Query: 207 ------EKMQREEQCILYLGPRYGFGEAGKPKFG----IEPNAELIYEVTLKS 249 M + L + P +G+ G G I P + L++++ Sbjct: 75 LGSDGIPPMLTGGKRTLRIPPELAYGDRGAGCKGGSCLIPPASVLLFDIEYIG 127 >3EY6-A nrPDB Length = 121 Score = 128 bits (321), Expect = 6e-30, Method: Composition-based stats. Identities = 33/120 (27%), Positives = 59/120 (49%), Gaps = 7/120 (5%) Query: 141 DLFEDGGIIRRTKRKGE-GYSNPNEGATVEIHLEGRC--GGRMFDCRDVAFTVGEGEDHD 197 D+ +G + ++T G G S P +G V +HL+ G R+ + ++ FT+G D D Sbjct: 6 DILGNGLLRKKTLVPGPPGSSRPVKGQVVTVHLQTSLENGTRVQEEPELVFTLG---DCD 62 Query: 198 IPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTLKSFEKAKESW 257 + +D ++ M E ++ +Y +G G+ + I P+A L EVTLK+ + Sbjct: 63 VIQALDLSVPLMDVGETAMVTADSKYCYGPQGRSPY-IPPHAALCLEVTLKTAVDGPDLE 121 Score = 114 bits (286), Expect = 7e-26, Method: Composition-based stats. Identities = 37/102 (36%), Positives = 48/102 (47%), Gaps = 7/102 (6%) Query: 43 GEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEP-FVFSLGKGQVIKAWDIGVATMKKGE 101 G P+ G V VH + L NG + + EP VF+LG VI+A D+ V M GE Sbjct: 24 GSSRPVKGQVVTVHLQTSLENGTRV-----QEEPELVFTLGDCDVIQALDLSVPLMDVGE 78 Query: 102 ICHLLCKPEYAYGSAGSLPKIPSNATLFFEIEL-LDFKGEDL 142 + +Y YG G P IP +A L E+ L G DL Sbjct: 79 TAMVTADSKYCYGPQGRSPYIPPHAALCLEVTLKTAVDGPDL 120 >2MF9-A nrPDB Length = 157 Score = 127 bits (320), Expect = 8e-30, Method: Composition-based stats. Identities = 33/117 (28%), Positives = 57/117 (48%), Gaps = 6/117 (5%) Query: 141 DLFEDGGIIRRTKRKGE-GYSNPNEGATVEIHLEGRC--GGRMFDCRDVAFTVGEGEDHD 197 D+ +G + ++T G G S P +G V +HL+ G R+ + ++ FT+G D D Sbjct: 38 DILGNGLLRKKTLVPGPPGSSRPVKGQVVTVHLQTSLENGTRVQEEPELVFTLG---DCD 94 Query: 198 IPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTLKSFEKAK 254 + +D ++ M E ++ +Y +G G I P+A L EVTLK+ + Sbjct: 95 VIQALDLSVPLMDVGETAMVTADSKYCYGPQGSRSPYIPPHAALCLEVTLKTAVDLE 151 Score = 106 bits (264), Expect = 2e-23, Method: Composition-based stats. Identities = 35/94 (37%), Positives = 46/94 (48%), Gaps = 7/94 (7%) Query: 43 GEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEP-FVFSLGKGQVIKAWDIGVATMKKGE 101 G P+ G V VH + L NG + + EP VF+LG VI+A D+ V M GE Sbjct: 56 GSSRPVKGQVVTVHLQTSLENGTRV-----QEEPELVFTLGDCDVIQALDLSVPLMDVGE 110 Query: 102 ICHLLCKPEYAYGSAGS-LPKIPSNATLFFEIEL 134 + +Y YG GS P IP +A L E+ L Sbjct: 111 TAMVTADSKYCYGPQGSRSPYIPPHAALCLEVTL 144 >1FD9-A nrPDB Length = 213 Score = 127 bits (319), Expect = 1e-29, Method: Composition-based stats. Identities = 40/138 (28%), Positives = 52/138 (37%), Gaps = 6/138 (4%) Query: 3 TDEGAKNNEESPTATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGKLS 62 DE E T + G + G+ V GNG P D V V Y G+L Sbjct: 81 ADENKVKGEAFLTENKNKPGVVVLPS---GLQYKVINSGNGV-KPGKSDTVTVEYTGRLI 136 Query: 63 NGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLPKI 122 +G FDS+ +P F + QVI W + M G + AYG I Sbjct: 137 DGTVFDSTEKTGKPATFQV--SQVIPGWTEALQLMPAGSTWEIYVPSGLAYGPRSVGGPI 194 Query: 123 PSNATLFFEIELLDFKGE 140 N TL F+I L+ K Sbjct: 195 GPNETLIFKIHLISVKKS 212 Score = 70.5 bits (171), Expect = 2e-12, Method: Composition-based stats. Identities = 25/109 (22%), Positives = 43/109 (39%), Gaps = 3/109 (2%) Query: 147 GIIRRTKRKGEGYSNPNEGATVEIHLEGRC-GGRMFDCRDVAFTVGEGEDHDIPIGIDKA 205 G+ + G G P + TV + GR G +FD + + + G +A Sbjct: 107 GLQYKVINSGNGV-KPGKSDTVTVEYTGRLIDGTVFDSTEKTGKPATFQVSQVIPGWTEA 165 Query: 206 LEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTLKSFEKAK 254 L+ M +Y+ +G I PN LI+++ L S +K+ Sbjct: 166 LQLMPAGSTWEIYVPSGLAYGPRSVGGP-IGPNETLIFKIHLISVKKSS 213 >1A17-A nrPDB Length = 166 Score = 125 bits (314), Expect = 4e-29, Method: Composition-based stats. Identities = 39/153 (25%), Positives = 67/153 (43%), Gaps = 16/153 (10%) Query: 256 SWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYGLSEKESKASESF 315 E L++A +K + YFK Y A+ Y + + E S + Sbjct: 1 RDEPPADGALKRAEELKTQANDYFKAKDYENAIKFYSQAI------------ELNPSNAI 48 Query: 316 LLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFE 375 + N ++ YL+ Y A+ +A+ LD KG YRR + + + +F +A D+E Sbjct: 49 Y---YGNRSLAYLRTECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYE 105 Query: 376 KVLEVNPQNKAARLQISMCQKKAKEHNERDRRI 408 V++V P +K A+++ C K K +R I Sbjct: 106 TVVKVKPHDKDAKMKYQECNKIVK-QKAFERAI 137 >5XB0-A nrPDB Length = 133 Score = 122 bits (307), Expect = 2e-28, Method: Composition-based stats. Identities = 43/134 (32%), Positives = 58/134 (43%), Gaps = 13/134 (9%) Query: 12 ESPT--ATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDK------VYVHYKGKLSN 63 ++PT A AE+ K GV ++ + E TP G K V V Y G+L + Sbjct: 3 DAPTEAALKAERTFMAGEKAKPGVKELADGILMTELTPGTGPKPDANGRVEVRYVGRLPD 62 Query: 64 GKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLPKIP 123 GK FD S +P F L VI W + M G L+ + AYG+ G+ I Sbjct: 63 GKIFDQS---TQPQWFRLD--SVISGWTSALQNMPTGAKWRLVIPSDQAYGAEGAGDLID 117 Query: 124 SNATLFFEIELLDF 137 L FEIEL+ Sbjct: 118 PFTPLVFEIELIAV 131 Score = 62.4 bits (150), Expect = 3e-10, Method: Composition-based stats. Identities = 25/107 (23%), Positives = 41/107 (38%), Gaps = 10/107 (9%) Query: 147 GIIRRTKRKGEGYSNPNEGATVEIHLEGRC-GGRMFDCRDVA--FTVGEGEDHDIPIGID 203 GI+ G G P+ VE+ GR G++FD F + + G Sbjct: 32 GILMTELTPGTG-PKPDANGRVEVRYVGRLPDGKIFDQSTQPQWFRL-----DSVISGWT 85 Query: 204 KALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTLKSF 250 AL+ M + L + +G G I+P L++E+ L + Sbjct: 86 SALQNMPTGAKWRLVIPSDQAYGAEGAGDL-IDPFTPLVFEIELIAV 131 >4BF8-A nrPDB Length = 117 Score = 118 bits (295), Expect = 6e-27, Method: Composition-based stats. Identities = 43/109 (39%), Positives = 62/109 (56%), Gaps = 3/109 (2%) Query: 30 DRGVLKIVKRVGNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVIKA 89 + G++ + G G G +V + Y GKL NGK FD + + +PFVF LG+G+VIK Sbjct: 12 EGGIIIEDRVTGKGPHA-KKGTRVGMRYVGKLKNGKVFDKN-TKGKPFVFKLGQGEVIKG 69 Query: 90 WDIGVATMKKGEICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELLDFK 138 WDIGVA M G ++ YAYG IP+N+ L F+++L+ K Sbjct: 70 WDIGVAGMAVGGERRIVIPAPYAYGKQALPG-IPANSELTFDVKLVSMK 117 Score = 78.6 bits (192), Expect = 5e-15, Method: Composition-based stats. Identities = 30/112 (26%), Positives = 53/112 (47%), Gaps = 11/112 (9%) Query: 145 DGGIIRRTKRKGEGYSNPNEGATVEIHLEGRC-GGRMFDC----RDVAFTVGEGEDHDIP 199 +GGII + G+G + +G V + G+ G++FD + F +G+GE + Sbjct: 12 EGGIIIEDRVTGKG-PHAKKGTRVGMRYVGKLKNGKVFDKNTKGKPFVFKLGQGE---VI 67 Query: 200 IGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTLKSFE 251 G D + M + + + Y +G+ P GI N+EL ++V L S + Sbjct: 68 KGWDIGVAGMAVGGERRIVIPAPYAYGKQALP--GIPANSELTFDVKLVSMK 117 >4DIP-A nrPDB Length = 125 Score = 116 bits (291), Expect = 2e-26, Method: Composition-based stats. Identities = 37/114 (32%), Positives = 58/114 (50%), Gaps = 4/114 (3%) Query: 28 KKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGKLS-NGKKFDSSHDRN--EPFVFSLGKG 84 + ++++++ GD + VHY+G L +G F S+H N +P F+LG Sbjct: 10 PEPEVKIEVLQKPFICHRKTKGGDLMLVHYEGYLEKDGSLFHSTHKHNNGQPIWFTLGIL 69 Query: 85 QVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELLDFK 138 + +K WD G+ M GE L+ P YG G KIP +TL F I+LL+ + Sbjct: 70 EALKGWDQGLKGMCVGEKRKLIIPPALGYGKEGK-GKIPPESTLIFNIDLLEIR 122 Score = 74.4 bits (181), Expect = 9e-14, Method: Composition-based stats. Identities = 28/115 (24%), Positives = 46/115 (40%), Gaps = 14/115 (12%) Query: 149 IRRTKRKGEGYSNPNEGATVEIHLEGRC--GGRMFDC-------RDVAFTVGEGEDHDIP 199 I ++ + G + +H EG G +F + + FT+G E Sbjct: 16 IEVLQKPFICHRKTKGGDLMLVHYEGYLEKDGSLFHSTHKHNNGQPIWFTLGILEAL--- 72 Query: 200 IGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTLKSFEKAK 254 G D+ L+ M E+ L + P G+G+ GK K I P + LI+ + L Sbjct: 73 KGWDQGLKGMCVGEKRKLIIPPALGYGKEGKGK--IPPESTLIFNIDLLEIRNGP 125 >4MSP-A nrPDB Length = 200 Score = 116 bits (291), Expect = 2e-26, Method: Composition-based stats. Identities = 48/181 (26%), Positives = 77/181 (42%), Gaps = 14/181 (7%) Query: 18 VAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGKLS-NGKKFDSSHDRN-- 74 +A+ G + + ++++++ GD + VHY+G L +G F S+H N Sbjct: 2 MADIGSEFLIPEPEVKIEVLQKPFICHRKTKGGDLMLVHYEGYLEKDGSLFHSTHKHNNG 61 Query: 75 EPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLPKIPSNATLFFEIEL 134 +P F+LG + +K WD G+ M GE L+ P YG G KIP +TL F I+L Sbjct: 62 QPIWFTLGILEALKGWDQGLKGMCVGEKRKLIIPPALGYGKEGK-GKIPPESTLIFNIDL 120 Query: 135 LDFKG----------EDLFEDGGIIRRTKRKGEGYSNPNEGATVEIHLEGRCGGRMFDCR 184 L+ + DL +D + + + GA V +FD Sbjct: 121 LEIRNGPRSHESFQEMDLNDDWKLSKDEVKAYLKKEFEKHGAVVNESHHDALVEDIFDKE 180 Query: 185 D 185 D Sbjct: 181 D 181 Score = 72.1 bits (175), Expect = 5e-13, Method: Composition-based stats. Identities = 30/119 (25%), Positives = 48/119 (40%), Gaps = 14/119 (11%) Query: 149 IRRTKRKGEGYSNPNEGATVEIHLEGRC--GGRMFDC-------RDVAFTVGEGEDHDIP 199 I ++ + G + +H EG G +F + + FT+G E Sbjct: 18 IEVLQKPFICHRKTKGGDLMLVHYEGYLEKDGSLFHSTHKHNNGQPIWFTLGILEAL--- 74 Query: 200 IGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTLKSFEKAKESWE 258 G D+ L+ M E+ L + P G+G+ GK K I P + LI+ + L S E Sbjct: 75 KGWDQGLKGMCVGEKRKLIIPPALGYGKEGKGK--IPPESTLIFNIDLLEIRNGPRSHE 131 >2C2L-A nrPDB Length = 281 Score = 115 bits (287), Expect = 4e-26, Method: Composition-based stats. Identities = 29/118 (24%), Positives = 55/118 (46%), Gaps = 15/118 (12%) Query: 268 AAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYGLSEKESKASESFLLAAFLNLAMCY 327 A +KE+G F G KY +A YG+ ++ + + N A+CY Sbjct: 4 AQELKEQGNRLFVGRKYPEAAACYGRAIT---------------RNPLVAVYYTNRALCY 48 Query: 328 LKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEVNPQNK 385 LK+++ +A+ C +AL LD + K + G+ QL M ++ A + ++ + + + Sbjct: 49 LKMQQPEQALADCRRALELDGQSVKAHFFLGQCQLEMESYDEAIANLQRAYSLAKEQR 106 >1Q6H-A nrPDB Length = 224 Score = 113 bits (283), Expect = 2e-25, Method: Composition-based stats. Identities = 53/136 (38%), Positives = 72/136 (52%), Gaps = 5/136 (3%) Query: 4 DEGAKNNEESPTATVAEQGEDITSKKDR-GVLKIVKRVGNGEETPMIGDKVYVHYKGKLS 62 ++ A +NE + ++ K G++ V G GE P D V V+YKG L Sbjct: 93 EKDAADNEAKGKEYREKFAKEKGVKTSSTGLVYQVVEAGKGE-APKDSDTVVVNYKGTLI 151 Query: 63 NGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLPKI 122 +GK+FD+S+ R EP F L VI W G+ +KKG L+ PE AYG AG I Sbjct: 152 DGKEFDNSYTRGEPLSFRLDG--VIPGWTEGLKNIKKGGKIKLVIPPELAYGKAGVPG-I 208 Query: 123 PSNATLFFEIELLDFK 138 P N+TL F++ELLD K Sbjct: 209 PPNSTLVFDVELLDVK 224 Score = 65.1 bits (157), Expect = 6e-11, Method: Composition-based stats. Identities = 25/110 (22%), Positives = 50/110 (45%), Gaps = 4/110 (3%) Query: 143 FEDGGIIRRTKRKGEGYSNPNEGATVEIHLEGRC-GGRMFDCRDVAFTVGEGEDHDIPIG 201 G++ + G+G + P + TV ++ +G G+ FD + G Sbjct: 118 TSSTGLVYQVVEAGKGEA-PKDSDTVVVNYKGTLIDGKEFDNSYTRGEPLSFRLDGVIPG 176 Query: 202 IDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTLKSFE 251 + L+ +++ + L + P +G+AG P GI PN+ L+++V L + Sbjct: 177 WTEGLKNIKKGGKIKLVIPPELAYGKAGVP--GIPPNSTLVFDVELLDVK 224 >2F4E-A nrPDB Length = 180 Score = 113 bits (282), Expect = 2e-25, Method: Composition-based stats. Identities = 40/142 (28%), Positives = 64/142 (45%), Gaps = 5/142 (3%) Query: 1 MTTDEGAKNNEESPTATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGK 60 +T ++E S V + + D V K + + G+G P ++HY+ Sbjct: 19 VTEGSAVVHSEPSQEGNVPPKVDSEAEVLDEKVSKQIIKEGHGS-KPSKYSTCFLHYRAW 77 Query: 61 LSNGK-KFDSSHDRNEPFVFSLGK-GQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAG- 117 N + KF+ + +P LGK + + IGVA+MK GE + E AYG G Sbjct: 78 TKNSQHKFEDTWHEQQPIELVLGKEKKELAGLAIGVASMKSGERALVHVGWELAYGKEGN 137 Query: 118 -SLPKIPSNATLFFEIELLDFK 138 S P +P A L +E+E++ F Sbjct: 138 FSFPNVPPMADLLYEVEVIGFD 159 Score = 89.4 bits (220), Expect = 3e-18, Method: Composition-based stats. Identities = 28/134 (20%), Positives = 60/134 (44%), Gaps = 10/134 (7%) Query: 145 DGGIIRRTKRKGEGYSNPNEGATVEIHLEGRCGGRMFDCRDV-----AFTVGEGEDHDIP 199 D + ++ ++G G S P++ +T +H D + G++ Sbjct: 48 DEKVSKQIIKEGHG-SKPSKYSTCFLHYRAWTKNSQHKFEDTWHEQQPIELVLGKEKKEL 106 Query: 200 IGIDKALEKMQREEQCILYLGPRYGFGEAGKPKF-GIEPNAELIYEVTLKSFEKAKE--- 255 G+ + M+ E+ ++++G +G+ G F + P A+L+YEV + F++ KE Sbjct: 107 AGLAIGVASMKSGERALVHVGWELAYGKEGNFSFPNVPPMADLLYEVEVIGFDETKEGKA 166 Query: 256 SWEMDTKEKLEQAA 269 +M +E++ A Sbjct: 167 RSDMTVEERIGAAD 180 >2GW1-A nrPDB Length = 514 Score = 94.0 bits (232), Expect = 1e-19, Method: Composition-based stats. Identities = 30/123 (24%), Positives = 59/123 (47%), Gaps = 2/123 (1%) Query: 299 EMEYGLSEKESKASESF-LLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRR 357 G E KA E F + +++ +A+ + T+ DKAL LDS N Y R Sbjct: 251 NDPLGAHEDIKKAIELFPRVNSYIYMALIMADRNDSTEYYNYFDKALKLDSNNSSVYYHR 310 Query: 358 GEAQLLMNEFESAKGDFEKVLEVNPQNKAARLQISMCQKKAKEHNERDRRIYANMFKKFA 417 G+ ++ ++ A DF+K E++P+N +Q++ + + ++ + +++ +KF Sbjct: 311 GQMNFILQNYDQAGKDFDKAKELDPENIFPYIQLACLAYRENKFDDCET-LFSEAKRKFP 369 Query: 418 EQD 420 E Sbjct: 370 EAP 372 Score = 82.5 bits (202), Expect = 3e-16, Method: Composition-based stats. Identities = 41/171 (23%), Positives = 69/171 (40%), Gaps = 23/171 (13%) Query: 263 EKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYGLSEKESKASESFLLAAFLN 322 EK + A +K+KG +F+ KY A+ Y + E + N Sbjct: 1 EKDKYALALKDKGNQFFRNKKYDDAIKYYNWALELKEDPV----------------FYSN 44 Query: 323 LAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEVNP 382 L+ CY+ + + K VE KAL L K L RR A + +F A D VL +N Sbjct: 45 LSACYVSVGDLKKVVEMSTKALELKPDYSKVLLRRASANEGLGKFADAMFDL-SVLSLNG 103 Query: 383 QNKAARLQISMCQKKAKEHNERDRRIYANM------FKKFAEQDAKEEANK 427 A ++ + + K+ + + + ++ + + Q AKE +K Sbjct: 104 DFNDASIEPMLERNLNKQAMSKLKEKFGDIDTATATPTELSTQPAKERKDK 154 Score = 37.4 bits (85), Expect = 0.012, Method: Composition-based stats. Identities = 26/152 (17%), Positives = 53/152 (34%), Gaps = 18/152 (11%) Query: 250 FEKAKESWEMDTKEKLEQAAIVKEKGTVYFKG-------GKYMQAVIQYGKIVSWL---- 298 FE+ + D K K + A ++ G F +A+ + ++ S++ Sbjct: 219 FEEQLDKNNEDEKLKEKLAISLEHTGIFKFLKNDPLGAHEDIKKAIELFPRVNSYIYMAL 278 Query: 299 -------EMEYGLSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANE 351 EY ++ +S + + + L+ Y +A + DKA LD N Sbjct: 279 IMADRNDSTEYYNYFDKALKLDSNNSSVYYHRGQMNFILQNYDQAGKDFDKAKELDPENI 338 Query: 352 KGLYRRGEAQLLMNEFESAKGDFEKVLEVNPQ 383 + N+F+ + F + P+ Sbjct: 339 FPYIQLACLAYRENKFDDCETLFSEAKRKFPE 370 Score = 33.6 bits (75), Expect = 0.18, Method: Composition-based stats. Identities = 17/105 (16%), Positives = 36/105 (34%), Gaps = 14/105 (13%) Query: 281 GGKYMQAVIQYGKIVSWLEM----EYGLSEKESKASESFLLAAFLNLAMCYLKLREYTKA 336 + +A+ QY + G++ KA+ N + +A Sbjct: 385 KNDFDKALKQYDLAIELENKLDGIYVGIAPLVGKATLLTRNPTVEN----------FIEA 434 Query: 337 VECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEVN 381 +KA LD +E+ + +L + + A FE+ ++ Sbjct: 435 TNLLEKASKLDPRSEQAKIGLAQMKLQQEDIDEAITLFEESADLA 479 Score = 29.7 bits (65), Expect = 2.7, Method: Composition-based stats. Identities = 27/150 (18%), Positives = 54/150 (36%), Gaps = 28/150 (18%) Query: 274 KGTVYFKGGKYMQAVIQYGKI----------------VSWLEMEYGLSE---KESKASES 314 +G + F Y QA + K +++ E ++ E E+K Sbjct: 310 RGQMNFILQNYDQAGKDFDKAKELDPENIFPYIQLACLAYRENKFDDCETLFSEAKRKFP 369 Query: 315 FLLAAFLNLAMCYLKLREYTKAVECCDKALGL----DSANEKGLYRRGEAQLL-----MN 365 A ++ KA++ D A+ L D G+A LL + Sbjct: 370 EAPEVPNFFAEILTDKNDFDKALKQYDLAIELENKLDGIYVGIAPLVGKATLLTRNPTVE 429 Query: 366 EFESAKGDFEKVLEVNPQNKAARLQISMCQ 395 F A EK +++P+++ A++ ++ + Sbjct: 430 NFIEATNLLEKASKLDPRSEQAKIGLAQMK 459 >6H3J-B nrPDB Length = 176 Score = 91.7 bits (226), Expect = 6e-19, Method: Composition-based stats. Identities = 31/92 (33%), Positives = 41/92 (44%), Gaps = 6/92 (6%) Query: 47 PMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLL 106 P + + V YKG +NGK FD S E +SL +I W G+ +K G L Sbjct: 91 PTLNSNITVIYKGYFTNGKVFDES---TEGVSYSL--RTLIPGWKEGIPLLKSGGEIQLF 145 Query: 107 CKPEYAYGSAGSLPKIPSNATLFFEIELLDFK 138 YGS G+ +P A L FEI L+ Sbjct: 146 VPAHLGYGSNGN-KTVPGGAVLIFEITLVSVN 176 Score = 54.7 bits (130), Expect = 9e-08, Method: Composition-based stats. Identities = 18/92 (19%), Positives = 40/92 (43%), Gaps = 10/92 (10%) Query: 162 PNEGATVEIHLEGRC-GGRMFDC--RDVAFTVGEGEDHDIPIGIDKALEKMQREEQCILY 218 P + + + +G G++FD V++++ + G + + ++ + L+ Sbjct: 91 PTLNSNITVIYKGYFTNGKVFDESTEGVSYSL-----RTLIPGWKEGIPLLKSGGEIQLF 145 Query: 219 LGPRYGFGEAGKPKFGIEPNAELIYEVTLKSF 250 + G+G G + A LI+E+TL S Sbjct: 146 VPAHLGYGSNGNK--TVPGGAVLIFEITLVSV 175 >2LKN-A nrPDB Length = 165 Score = 86.7 bits (213), Expect = 2e-17, Method: Composition-based stats. Identities = 29/89 (32%), Positives = 43/89 (48%), Gaps = 4/89 (4%) Query: 24 DITSK-KDRGVLKIVKRVGNGEETPMI-GDKVYVHYKGKLSN--GKKFDSSHDRNEPFVF 79 DI ++ ++ G+ K V + G GE G K HY+ S+ G D S R +P Sbjct: 2 DIIARLREDGIQKRVIQEGRGELPDFQDGTKATFHYRTLHSDDEGTVLDDSRARGKPMEL 61 Query: 80 SLGKGQVIKAWDIGVATMKKGEICHLLCK 108 +GK + W+ V TM++GEI LC Sbjct: 62 IIGKKFKLPVWETIVCTMREGEIAQFLCD 90 Score = 38.9 bits (89), Expect = 0.005, Method: Composition-based stats. Identities = 15/86 (17%), Positives = 28/86 (32%), Gaps = 10/86 (11%) Query: 143 FEDGGIIRRTKRKGEGYSNP--NEGATVEIHLEGRCG---GRMFD---CRDVAFTVGEGE 194 + GI +R ++G G P +G H G + D R + G+ Sbjct: 7 LREDGIQKRVIQEGRG-ELPDFQDGTKATFHYRTLHSDDEGTVLDDSRARGKPMELIIGK 65 Query: 195 DHDIPIGIDKALEKMQREEQCILYLG 220 +P+ + + M+ E Sbjct: 66 KFKLPV-WETIVCTMREGEIAQFLCD 90 >1IX5-A nrPDB Length = 151 Score = 76.7 bits (187), Expect = 2e-14, Method: Composition-based stats. Identities = 42/162 (25%), Positives = 65/162 (40%), Gaps = 33/162 (20%) Query: 49 IGDKVYVHYKGKLSNGKKFDSS------------HDRN-EPFVFSLGKGQVIKAWDIGVA 95 G K+ V Y GKL +G FD+S DR EP F +G+GQ+I+ ++ V Sbjct: 4 KGVKIKVDYIGKLESGDVFDTSIEEVAKEAGIYAPDREYEPLEFVVGEGQLIQGFEEAVL 63 Query: 96 TMKKGEICHLLCKPEYAYGSAGSL--PKIPSNATLFFEIELLDFKGEDLFEDGGIIRRTK 153 M+ G+ + E AYG+ + KIP +A FK D + G++ Sbjct: 64 DMEVGDEKTVKIPAEKAYGNRNEMLIQKIPRDA----------FKEADFEPEEGMV--IL 111 Query: 154 RKG-EGYSNPNEGATVEIHLEGRCGGRMFDCRDVAFTVGEGE 194 +G V + G+ D+ FT+ E Sbjct: 112 AEGIPATITEVTDNEVTLDFNHELAGK-----DLVFTIKIIE 148 Score = 36.6 bits (83), Expect = 0.021, Method: Composition-based stats. Identities = 14/84 (16%), Positives = 32/84 (38%), Gaps = 22/84 (26%) Query: 164 EGATVEIHLEGRC-GGRMFDC------------------RDVAFTVGEGEDHDIPIGIDK 204 +G +++ G+ G +FD + F VGEG+ + G ++ Sbjct: 4 KGVKIKVDYIGKLESGDVFDTSIEEVAKEAGIYAPDREYEPLEFVVGEGQ---LIQGFEE 60 Query: 205 ALEKMQREEQCILYLGPRYGFGEA 228 A+ M+ ++ + + +G Sbjct: 61 AVLDMEVGDEKTVKIPAEKAYGNR 84 >2Y4T-A nrPDB Length = 450 Score = 72.1 bits (175), Expect = 5e-13, Method: Composition-based stats. Identities = 33/192 (17%), Positives = 73/192 (38%), Gaps = 21/192 (10%) Query: 239 AELIYEV--TLKSFEKAKESWEMDTKEK--------LEQAAIVKEKGTVYFKGGKYMQAV 288 + L Y++ S + +E ++D K +++ + E + G+Y A Sbjct: 218 STLYYQLGDHELSLSEVRECLKLDQDHKRCFAHYKQVKKLNKLIESAEELIRDGRYTDAT 277 Query: 289 IQYGKIVSWLEMEYGLSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDS 348 +Y ++ + + + C+ K + +A+ C + L ++ Sbjct: 278 SKYESVMKTEPSIAEYTVRSKERI------CH-----CFSKDEKPVEAIRVCSEVLQMEP 326 Query: 349 ANEKGLYRRGEAQLLMNEFESAKGDFEKVLEVNPQNKAARLQISMCQKKAKEHNERDRRI 408 N L R EA L+ ++ A D+E E N ++ R + Q+ K+ +RD Sbjct: 327 DNVNALKDRAEAYLIEEMYDEAIQDYETAQEHNENDQQIREGLEKAQRLLKQSQKRDYYK 386 Query: 409 YANMFKKFAEQD 420 + + +Q+ Sbjct: 387 ILGVKRNAKKQE 398 Score = 48.6 bits (114), Expect = 6e-06, Method: Composition-based stats. Identities = 21/92 (22%), Positives = 37/92 (40%) Query: 319 AFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVL 378 A+ A +L + + A+ K + L +RG L + + A+ DF+KVL Sbjct: 62 AYYRRATVFLAMGKSKAALPDLTKVIQLKMDFTAARLQRGHLLLKQGKLDEAEDDFKKVL 121 Query: 379 EVNPQNKAARLQISMCQKKAKEHNERDRRIYA 410 + NP + S K + R + + A Sbjct: 122 KSNPSENEEKEAQSQLIKSDEMQRLRSQALNA 153 Score = 47.0 bits (110), Expect = 2e-05, Method: Composition-based stats. Identities = 26/104 (25%), Positives = 41/104 (39%) Query: 320 FLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLE 379 L L L + A+ A+ D N YRR L M + ++A D KV++ Sbjct: 29 HLELGKKLLAAGQLADALSQFHAAVDGDPDNYIAYYRRATVFLAMGKSKAALPDLTKVIQ 88 Query: 380 VNPQNKAARLQISMCQKKAKEHNERDRRIYANMFKKFAEQDAKE 423 + AARLQ K + +E + + +E + KE Sbjct: 89 LKMDFTAARLQRGHLLLKQGKLDEAEDDFKKVLKSNPSENEEKE 132 >4ODP-A nrPDB Length = 110 Score = 66.7 bits (161), Expect = 2e-11, Method: Composition-based stats. Identities = 20/87 (22%), Positives = 37/87 (42%), Gaps = 6/87 (6%) Query: 52 KVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEY 111 V + Y ++ G+ D + G +I + + ++GE E Sbjct: 8 VVTIRYTLQVE-GEVLDQGE-----LSYLHGHRNLIPGLEEALEGREEGEAFQAHVPAEK 61 Query: 112 AYGSAGSLPKIPSNATLFFEIELLDFK 138 AYG+ G IP +ATL F++E++ + Sbjct: 62 AYGATGHPGIIPPHATLDFQVEVVKVR 88 Score = 55.9 bits (133), Expect = 4e-08, Method: Composition-based stats. Identities = 19/94 (20%), Positives = 40/94 (42%), Gaps = 4/94 (4%) Query: 166 ATVEIHLEGRCGGRMFDCRDVAFTVGEGEDHDIPIGIDKALEKMQREEQCILYLGPRYGF 225 V I + G + D ++++ G ++ G+++ALE + E ++ + Sbjct: 7 KVVTIRYTLQVEGEVLDQGELSYLHGH---RNLIPGLEEALEGREEGEAFQAHVPAEKAY 63 Query: 226 GEAGKPKFGIEPNAELIYEVTLKSFEKAKESWEM 259 G G P I P+A L ++V + +A + Sbjct: 64 GATGHPGI-IPPHATLDFQVEVVKVREATPEELL 96 >4DT4-A nrPDB Length = 169 Score = 59.4 bits (142), Expect = 3e-09, Method: Composition-based stats. Identities = 32/131 (24%), Positives = 56/131 (42%), Gaps = 14/131 (10%) Query: 50 GDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKP 109 V VH+ KL +G +S+ + +P +F LG + + + + +K G+ +P Sbjct: 28 NSAVLVHFTLKLDDGTTAESTRNNGKPALFRLGDASLSEGLEQHLLGLKVGDKTTFSLEP 87 Query: 110 EYAYGSAGSLPKIPSNATLFF------EI-ELLDFKGEDLFEDGGIIRRTKRKGEG---- 158 + A+G S I + F EI ++ F D E G+IR G+ Sbjct: 88 DAAFGVP-SPDLIQYFSRREFMDAGEPEIGAIMLFTAMDGSEMPGVIREI--NGDSITVD 144 Query: 159 YSNPNEGATVE 169 +++P G TV Sbjct: 145 FNHPLAGQTVH 155 >2M2A-A nrPDB Length = 148 Score = 59.4 bits (142), Expect = 3e-09, Method: Composition-based stats. Identities = 32/131 (24%), Positives = 56/131 (42%), Gaps = 14/131 (10%) Query: 50 GDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKP 109 V VH+ KL +G +S+ + +P +F LG + + + + +K G+ +P Sbjct: 8 NSAVLVHFTLKLDDGTTAESTRNNGKPALFRLGDASLSEGLEQHLLGLKVGDKTTFSLEP 67 Query: 110 EYAYGSAGSLPKIPSNATLFF------EI-ELLDFKGEDLFEDGGIIRRTKRKGEG---- 158 + A+G S I + F EI ++ F D E G+IR G+ Sbjct: 68 DAAFGVP-SPDLIQYFSRREFMDAGEPEIGAIMLFTAMDGSEMPGVIREI--NGDSITVD 124 Query: 159 YSNPNEGATVE 169 +++P G TV Sbjct: 125 FNHPLAGQTVH 135 >3PRA-A nrPDB Length = 157 Score = 57.8 bits (138), Expect = 9e-09, Method: Composition-based stats. Identities = 23/90 (25%), Positives = 37/90 (41%), Gaps = 16/90 (17%) Query: 49 IGDKVYVHYKGKLSNGKKFDSSHDRNE-------------PFVFSLGKGQVIKAWDIGVA 95 G V + Y G + +GK FD++++ P G+GQV+ D + Sbjct: 4 KGKMVKISYDGYV-DGKLFDTTNEELAKKEGIYNPAMIYGPVAIFAGEGQVLPGLDEAIL 62 Query: 96 TMKKGEICHLLCKPEYAYGSA--GSLPKIP 123 M GE ++ PE A+G + IP Sbjct: 63 EMDVGEEREVVLPPEKAFGKRDPSKIKLIP 92 Score = 48.6 bits (114), Expect = 5e-06, Method: Composition-based stats. Identities = 21/94 (22%), Positives = 38/94 (40%), Gaps = 15/94 (15%) Query: 164 EGATVEIHLEGRCGGRMFDCRDVAFTVGEG---------------EDHDIPIGIDKALEK 208 +G V+I +G G++FD + EG + + G+D+A+ + Sbjct: 4 KGKMVKISYDGYVDGKLFDTTNEELAKKEGIYNPAMIYGPVAIFAGEGQVLPGLDEAILE 63 Query: 209 MQREEQCILYLGPRYGFGEAGKPKFGIEPNAELI 242 M E+ + L P FG+ K + P +E Sbjct: 64 MDVGEEREVVLPPEKAFGKRDPSKIKLIPLSEFT 97 >6B85-J nrPDB Length = 223 Score = 57.1 bits (136), Expect = 2e-08, Method: Composition-based stats. Identities = 21/128 (16%), Positives = 44/128 (34%), Gaps = 16/128 (12%) Query: 287 AVIQYGKIVSWLEMEYGLSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGL 346 A Y K + E +++ L L KL+ +A E KA+ L Sbjct: 100 AAEAYKKAI------------ELDPNDALAW---LLLGSVLEKLKRLDEAAEAYKKAIEL 144 Query: 347 DSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEVNPQNKAARLQISMCQKKAKEHNERDR 406 + G+ + + A ++K +E++P++ A ++ +K + Sbjct: 145 KPNDASAWKELGKVLEKLGRLDEAAEAYKKAIELDPEDAEAWKELGKVLEKLGRL-DEAA 203 Query: 407 RIYANMFK 414 Y + Sbjct: 204 EAYKKAIE 211 Score = 55.9 bits (133), Expect = 4e-08, Method: Composition-based stats. Identities = 22/110 (20%), Positives = 42/110 (38%), Gaps = 15/110 (13%) Query: 275 GTVYFKGGKYMQAVIQYGKIVSWLEMEYGLSEKESKASESFLLAAFLNLAMCYLKLREYT 334 G+V K + +A Y K + E K +++ L KL Sbjct: 122 GSVLEKLKRLDEAAEAYKKAI------------ELKPNDASAWK---ELGKVLEKLGRLD 166 Query: 335 KAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEVNPQN 384 +A E KA+ LD + + G+ + + A ++K +E++P + Sbjct: 167 EAAEAYKKAIELDPEDAEAWKELGKVLEKLGRLDEAAEAYKKAIELDPND 216 Score = 50.1 bits (118), Expect = 2e-06, Method: Composition-based stats. Identities = 19/96 (19%), Positives = 35/96 (36%), Gaps = 4/96 (4%) Query: 336 AVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEVNPQNKAARLQISMCQ 395 A E KA+ LD + G + + A ++K +E+ P + +A ++ Sbjct: 100 AAEAYKKAIELDPNDALAWLLLGSVLEKLKRLDEAAEAYKKAIELKPNDASAWKELGKVL 159 Query: 396 KKAKEHNERDRRIYANMFKKFAEQDAKEEANKAMGK 431 +K + Y + EA K +GK Sbjct: 160 EKLGRL-DEAAEAYKKAIE---LDPEDAEAWKELGK 191 Score = 38.6 bits (88), Expect = 0.006, Method: Composition-based stats. Identities = 27/110 (24%), Positives = 44/110 (40%), Gaps = 15/110 (13%) Query: 247 LKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYGLSE 306 LK ++A E+++ + K A+ KE G V K G+ +A Y K + L+ E + Sbjct: 128 LKRLDEAAEAYKKAIELKPNDASAWKELGKVLEKLGRLDEAAEAYKKAIE-LDPEDAEAW 186 Query: 307 KESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYR 356 KE KL +A E KA+ LD + + + Sbjct: 187 KELGKVLE--------------KLGRLDEAAEAYKKAIELDPNDLEHHHH 222 >3PRB-A nrPDB Length = 231 Score = 56.7 bits (135), Expect = 2e-08, Method: Composition-based stats. Identities = 46/243 (18%), Positives = 85/243 (34%), Gaps = 34/243 (13%) Query: 49 IGDKVYVHYKGKLSNGKKFDSSHDRNE-------------PFVFSLGKGQVIKAWDIGVA 95 G V + Y G + +GK FD++++ P G+GQV+ D + Sbjct: 4 KGKMVKISYDGYV-DGKLFDTTNEELAKKEGIYNPAMIYGPVAIFAGEGQVLPGLDEAIL 62 Query: 96 TMKKGEICHLLCKPEYAYGSA--GSLPKIPSNATLFFEIELLDFKGEDLFEDGGIIRRTK 153 M GE ++ PE A+G + IP L +F + G+ Sbjct: 63 EMDVGEEREVVLPPEKAFGKRDPSKIKLIP----------LSEFTKRGIKPIKGLTITID 112 Query: 154 RKGEGYSNPNEGATVEIHLEGRCGGRMFDCRDVAFTVGEGEDHDIPIGIDKALEKMQREE 213 + N G V + G+ +V + + E D I K + KM Sbjct: 113 GIPGKIVSINSG-RVLVDFNHELAGK-----EVKYRIKIEEVVDDKKNIVKEIVKMYVPR 166 Query: 214 QCILYLGPRYGFGEAGKPKFG--IEPNAELIYEVTLKSFEKAKESWEMDTKEKLEQAAIV 271 + + R G + P+F I + + ++ +++ ++ E E+ Sbjct: 167 LSDVKVTIRNGTVKIELPEFAPFIPNIQTAKMAIANEILKRLEDAEKVSFVETFERKKET 226 Query: 272 KEK 274 KE+ Sbjct: 227 KEE 229 >5AEM-A nrPDB Length = 447 Score = 54.7 bits (130), Expect = 9e-08, Method: Composition-based stats. Identities = 30/198 (15%), Positives = 65/198 (32%), Gaps = 35/198 (17%) Query: 274 KGTVYFKGGKYMQAVIQYGKIVSWLEMEYGLSE----------KESKASESFLLAAFLN- 322 + F A + +++ + E + + S+ LAA LN Sbjct: 15 QANEAFVRNDLQVAERLFNEVIKKDARNFAAYETLGDIYQLQGRLNDCCNSWFLAAHLNA 74 Query: 323 --------LAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDF 374 +A+ L +A+ C + + L+ + +YRR + A F Sbjct: 75 SDWEFWKIVAILSADLDHVRQAIYCFSRVISLNPMEWESIYRRSMLYKKTGQLARALDGF 134 Query: 375 EKVLEVNPQNKAARLQISMC--------------QKKAKEHNERDRRIYANMFKKF--AE 418 +++ NP + ++++ K + ER I A + ++ Sbjct: 135 QRLYMYNPYDANILRELAILYVDYDRIEDSIELYMKVFNANVERREAILAALENALDSSD 194 Query: 419 QDAKEEANKAMGKKTSEG 436 +++ E A K+ E Sbjct: 195 EESAAEGEDADEKEPLEQ 212 >5G04-F nrPDB Length = 824 Score = 54.0 bits (128), Expect = 1e-07, Method: Composition-based stats. Identities = 33/197 (16%), Positives = 70/197 (35%), Gaps = 34/197 (17%) Query: 275 GTVYFKGGKYMQAVIQYGKIVSWLEMEYGLSEKESKASESFLLAAFLNLAMCYLKLREYT 334 G +Y+K K+ A + + K + + S LL + + L++ Sbjct: 642 GMIYYKQEKFSLAEMHFQKAL------------DINPQSSVLL-CH--IGVVQHALKKSE 686 Query: 335 KAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEVNPQNKAARLQISMC 394 KA++ +KA+ +D N + R +++SA + E++ ++ P+ I Sbjct: 687 KALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIGKV 746 Query: 395 QKKA------------------KEHNERDRRIYANMFKKFAEQDAKEEANKAMGKKTSE- 435 KK K N + + + E+ +E ++ E Sbjct: 747 YKKLGQTHLALMNFSWAMDLDPKGANNQIKEAIDKRYLPDDEEPITQEEQIMGTDESQES 806 Query: 436 GVTNEKGTDSQAMEEEK 452 +T+ T A E ++ Sbjct: 807 SMTDADDTQLHAAESDE 823 Score = 52.8 bits (125), Expect = 3e-07, Method: Composition-based stats. Identities = 31/156 (19%), Positives = 58/156 (37%), Gaps = 22/156 (14%) Query: 275 GTVYFKGGKYMQAVIQYGKIVS----------WLEMEYGLSEKESKASESFLLAAFLN-- 322 G + ++ A+ + + + L E+ L+E+ KA F A +N Sbjct: 574 GNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPR 633 Query: 323 -------LAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFE 375 L M Y K +++ A KAL ++ + L G Q + + E A Sbjct: 634 HYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLN 693 Query: 376 KVLEVNPQN---KAARLQISMCQKKAKEHNERDRRI 408 K + ++P+N K R + +K K + + Sbjct: 694 KAIVIDPKNPLCKFHRASVLFANEKYKSALQELEEL 729 >4JYS-A nrPDB Length = 138 Score = 53.6 bits (127), Expect = 2e-07, Method: Composition-based stats. Identities = 32/130 (24%), Positives = 54/130 (41%), Gaps = 10/130 (7%) Query: 28 KKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGKLSNG-KKFDSSHDRNEPFVFSLGK--G 84 K + G+L G G+ GD VY+HY+GK +N + S+ + P G+ Sbjct: 10 KTESGILYKDLIDGEGD-PIEEGDIVYIHYQGKTTNDFRIIHSTFNSIIPPKIRAGQYDQ 68 Query: 85 QVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELLDFKGEDLFE 144 + I+A V MKK + P AY P + L +EI+++ +D Sbjct: 69 KHIRAIYEIVIGMKKHTRRQCVVPPHLAY------PNHFPSQPLLYEIDVVKVVKKDSQG 122 Query: 145 DGGIIRRTKR 154 I + ++ Sbjct: 123 KTFIEKVEQK 132 Score = 34.7 bits (78), Expect = 0.094, Method: Composition-based stats. Identities = 28/137 (20%), Positives = 51/137 (37%), Gaps = 17/137 (12%) Query: 138 KGEDLFEDGGIIRRTKRKGEGYSNPNEGATVEIHLEGRCGG------RMFDCRDVAFTVG 191 + + GI+ + GEG EG V IH +G+ F+ + + Sbjct: 5 DKPYVKTESGILYKDLIDGEG-DPIEEGDIVYIHYQGKTTNDFRIIHSTFNSI-IPPKIR 62 Query: 192 EGE-DHDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTLKSF 250 G+ D I + + M++ + + P + P+ L+YE+ + Sbjct: 63 AGQYDQKHIRAIYEIVIGMKKHTRRQCVVPPHLAY-------PNHFPSQPLLYEIDVVKV 115 Query: 251 EKAKESWEMDTKEKLEQ 267 K K+S EK+EQ Sbjct: 116 VK-KDSQGKTFIEKVEQ 131 >5U9A-A nrPDB Length = 169 Score = 52.4 bits (124), Expect = 4e-07, Method: Composition-based stats. Identities = 19/81 (23%), Positives = 33/81 (40%), Gaps = 3/81 (3%) Query: 31 RGVLKIVKRVGNGEETPMI-GDKVYVHYKGKLSNG--KKFDSSHDRNEPFVFSLGKGQVI 87 GV K + G GE I G +V H++ + D S +P +G + Sbjct: 18 EGVKKTILHGGTGELPNFITGSRVIFHFRTMKCDEERTVIDDSRQVGQPMHIIIGNMFKL 77 Query: 88 KAWDIGVATMKKGEICHLLCK 108 + W+I + +M+ E+ C Sbjct: 78 EVWEILLTSMRVHEVAEFWCD 98 >4CGU-A nrPDB Length = 112 Score = 51.7 bits (122), Expect = 7e-07, Method: Composition-based stats. Identities = 27/109 (24%), Positives = 44/109 (40%), Gaps = 21/109 (19%) Query: 265 LEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYGLSEKESKASESFLLAAFLNLA 324 + Q KE+G FK G Y +AV Y ++++ ++ + N A Sbjct: 2 MSQFEKQKEQGNSLFKQGLYREAVHCYDQLIT------------AQPQNPV---GYSNKA 46 Query: 325 MCYLKLREYTKAVECCDKAL------GLDSANEKGLYRRGEAQLLMNEF 367 M +KL EYT+A++ C + L + K YR AQ + Sbjct: 47 MALIKLGEYTQAIQMCQQGLRYTSTAEHVAIRSKLQYRLELAQGAVGSV 95 Score = 36.6 bits (83), Expect = 0.022, Method: Composition-based stats. Identities = 14/70 (20%), Positives = 27/70 (38%), Gaps = 2/70 (2%) Query: 326 CYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEV--NPQ 383 K Y +AV C D+ + N G + A + + E+ A ++ L + Sbjct: 14 SLFKQGLYREAVHCYDQLITAQPQNPVGYSNKAMALIKLGEYTQAIQMCQQGLRYTSTAE 73 Query: 384 NKAARLQISM 393 + A R ++ Sbjct: 74 HVAIRSKLQY 83 >5WQL-B nrPDB Length = 278 Score = 51.3 bits (121), Expect = 1e-06, Method: Composition-based stats. Identities = 36/215 (16%), Positives = 66/215 (30%), Gaps = 33/215 (15%) Query: 235 IEPNAELIYEVTLKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKI 294 + L EV L E+ S + E+ A ++ E+G +Y G A + + Sbjct: 16 VPLQPTLQQEVILARMEQILASRALTDDER---AQLLYERGVLYDSLGLRALARNDFSQA 72 Query: 295 VSWLEMEYGLSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGL 354 + A + F L + + + A E D L LD Sbjct: 73 L---------------AIRPDMPEVFNYLGIYLTQAGNFDAAYEAFDSVLELDPTYNYAH 117 Query: 355 YRRGEAQLLMNEFESAKGDFEKVLEVNPQNKAARLQISMCQKKAKEHNERD--RRIYAN- 411 RG A + A+ D + +P + L + + ++K E ++ ++ + Sbjct: 118 LNRGIALYYGGRDKLAQDDLLAFYQDDPNDPFRSLWLYLAEQKLDEKQAKEVLKQHFEKS 177 Query: 412 ------------MFKKFAEQDAKEEANKAMGKKTS 434 +EQ E TS Sbjct: 178 DKEQWGWNIVEFYLGNISEQTLMERLKADATDNTS 212 >1W3B-A nrPDB Length = 388 Score = 50.9 bits (120), Expect = 1e-06, Method: Composition-based stats. Identities = 26/155 (16%), Positives = 49/155 (31%), Gaps = 17/155 (10%) Query: 275 GTVYFKGGKYMQAVIQYGKIVSWLEMEYGLSEKESKASESFLLAAFLNLAMCYLKLREYT 334 G V + + +AV Y + +S NLA Y + Sbjct: 210 GNVLKEARIFDRAVAAYLRALS---------------LSPNHAVVHGNLACVYYEQGLID 254 Query: 335 KAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEVNPQNKAARLQISMC 394 A++ +A+ L A A+ + L + P + + ++ Sbjct: 255 LAIDTYRRAIELQPHFPDAYCNLANALKEKGSVAEAEDCYNTALRLCPTHADSLNNLANI 314 Query: 395 QKKAKEHNERDRRIYANMFKKFAEQDAKEEANKAM 429 K+ + + E R+Y + F E A +N A Sbjct: 315 -KREQGNIEEAVRLYRKALEVFPEF-AAAHSNLAS 347 Score = 47.8 bits (112), Expect = 1e-05, Method: Composition-based stats. Identities = 25/120 (20%), Positives = 37/120 (30%), Gaps = 4/120 (3%) Query: 311 ASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESA 370 L A+ NL Y + + +A+E AL L G A + + E A Sbjct: 61 KQNPLLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDMEGA 120 Query: 371 KGDFEKVLEVNPQNKAARLQISMCQKKAKEHNERDRRIYANMFKKFAEQDAKEEANKAMG 430 + L+ NP R + K E + Y K Q A +G Sbjct: 121 VQAYVSALQYNPDLYCVRSDLGNLLKALGRL-EEAKACY---LKAIETQPNFAVAWSNLG 176 Score = 47.0 bits (110), Expect = 2e-05, Method: Composition-based stats. Identities = 28/171 (16%), Positives = 53/171 (30%), Gaps = 19/171 (11%) Query: 248 KSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSW---------- 297 + +++ + K+ A G VY + G+ +A+ Y + Sbjct: 47 RRLDRSAHFSTLAIKQNPLLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYIN 106 Query: 298 LEMEYGLSEKESKASESFLLAAFLN---------LAMCYLKLREYTKAVECCDKALGLDS 348 L + A ++++ A N L L +A C KA+ Sbjct: 107 LAAALVAAGDMEGAVQAYVSALQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQP 166 Query: 349 ANEKGLYRRGEAQLLMNEFESAKGDFEKVLEVNPQNKAARLQISMCQKKAK 399 G E A FEK + ++P A + + K+A+ Sbjct: 167 NFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEAR 217 Score = 44.3 bits (103), Expect = 1e-04, Method: Composition-based stats. Identities = 19/120 (15%), Positives = 41/120 (34%), Gaps = 15/120 (12%) Query: 273 EKGTVYFKGGKYMQAVIQYGKIVSWLEMEYGLSEKESKASESFLLAAFLNLAMCYLKLRE 332 + G + G+ +A Y K + E++ + + + NL + E Sbjct: 140 DLGNLLKALGRLEEAKACYLKAI------------ETQPNFAVAWS---NLGCVFNAQGE 184 Query: 333 YTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEVNPQNKAARLQIS 392 A+ +KA+ LD G F+ A + + L ++P + ++ Sbjct: 185 IWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLA 244 Score = 43.6 bits (101), Expect = 2e-04, Method: Composition-based stats. Identities = 21/150 (14%), Positives = 45/150 (30%), Gaps = 22/150 (14%) Query: 242 IYEVTLKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEME 301 + ++ + ++ +A E A +KEKG+V +A Y + Sbjct: 252 LIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGSVA-------EAEDCYNTALR----- 299 Query: 302 YGLSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQ 361 + NLA + +AV KAL + Sbjct: 300 ----------LCPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVL 349 Query: 362 LLMNEFESAKGDFEKVLEVNPQNKAARLQI 391 + + A +++ + ++P A + Sbjct: 350 QQQGKLQEALMHYKEAIRISPTFADAYSNM 379 >5FZQ-A nrPDB Length = 131 Score = 48.6 bits (114), Expect = 6e-06, Method: Composition-based stats. Identities = 19/110 (17%), Positives = 37/110 (33%), Gaps = 4/110 (3%) Query: 317 LAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEK 376 + NLA + + +A++ KA+ LD N K L + E A K Sbjct: 5 IKTLSNLANLLAQEGKAEEAIKYMRKAVSLDPNNIKTLSNLANLLAQEGKAEEAIKYMRK 64 Query: 377 VLEVNPQNKAARLQISMCQKKAKEHNERDRRIYANMFKKFAEQDAKEEAN 426 + ++P N +++ + M K + D + + Sbjct: 65 AVSLDPNNIKTLSNLAVLL----AQEGKAEEAIKYMRKAVSLIDKAAKGS 110 Score = 43.2 bits (100), Expect = 2e-04, Method: Composition-based stats. Identities = 23/118 (19%), Positives = 41/118 (34%), Gaps = 17/118 (14%) Query: 271 VKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYGLSEKESKASESFLLAAFLNLAMCYLKL 330 + + + GK +A+ K VS + + NLA + Sbjct: 8 LSNLANLLAQEGKAEEAIKYMRKAVS---------------LDPNNIKTLSNLANLLAQE 52 Query: 331 REYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEVNPQNKAAR 388 + +A++ KA+ LD N K L + E A K + + +KAA+ Sbjct: 53 GKAEEAIKYMRKAVSLDPNNIKTLSNLAVLLAQEGKAEEAIKYMRKAVSLI--DKAAK 108 Score = 30.1 bits (66), Expect = 2.0, Method: Composition-based stats. Identities = 9/77 (11%), Positives = 19/77 (24%), Gaps = 4/77 (5%) Query: 348 SANEKGLYRRGEAQLLMNEFESAKGDFEKVLEVNPQNKAARLQISMCQKKAKEHNERDRR 407 + K L + E A K + ++P N ++ + Sbjct: 2 GNSIKTLSNLANLLAQEGKAEEAIKYMRKAVSLDPNNIKTLSNLANLL----AQEGKAEE 57 Query: 408 IYANMFKKFAEQDAKEE 424 M K + + Sbjct: 58 AIKYMRKAVSLDPNNIK 74 >5OJ8-A nrPDB Length = 255 Score = 43.6 bits (101), Expect = 2e-04, Method: Composition-based stats. Identities = 30/212 (14%), Positives = 70/212 (33%), Gaps = 35/212 (16%) Query: 225 FGEAGKPKFGIEPNAELIYEVTLKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKY 284 + G+ + + + ++ + + + A ++ VY KY Sbjct: 60 YASQGRYEVAVP-----------LCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKY 108 Query: 285 MQAVIQYGKIVSWLEMEYGLSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKAL 344 A ++ + EK + A NLA+ Y K +Y +A C +AL Sbjct: 109 KDAANLLNDALA-------IREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRAL 161 Query: 345 GL--------DSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEVN-----PQNKAA---R 388 + K L ++E + +++ LE+ P + + Sbjct: 162 EIREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEYYYQRALEIYQTKLGPDDPNVAKTK 221 Query: 389 LQISMCQKKAKEHNERDRRIYANMFKKFAEQD 420 ++ C K + + + +Y + + E++ Sbjct: 222 NNLASCYLKQGKFKQAET-LYKEILTRAHERE 252 >5NNP-A nrPDB Length = 745 Score = 43.6 bits (101), Expect = 2e-04, Method: Composition-based stats. Identities = 24/133 (18%), Positives = 50/133 (37%), Gaps = 10/133 (7%) Query: 279 FKGGKYMQAVIQY-GKIVSWLEMEYGLSEKESKASES--FLLAAFLNLAMCYLKLREYTK 335 FK +Y + V+ + SK + + LA N M R+ T+ Sbjct: 337 FKKETLASLAEEYLNEYVNARPSDNQADGDGSKGKGAALYYLAQHYNYYMS----RDLTR 392 Query: 336 AVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEVNPQNKAARLQISMCQ 395 A+E +KA+ LD N + + A + ++P+++ + + Q Sbjct: 393 ALEYVEKAIELDPKNVDFHMTKARIFKHQGDLAKAAETMDYARSLDPKDRYINSKAAKYQ 452 Query: 396 KKAKEHNERDRRI 408 + +NE ++ + Sbjct: 453 LR---NNENEKAL 462 Score = 38.6 bits (88), Expect = 0.006, Method: Composition-based stats. Identities = 10/66 (15%), Positives = 28/66 (42%) Query: 334 TKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEVNPQNKAARLQISM 393 +A +AL +D + + G F+ A ++ L++ P++ + +++ Sbjct: 61 EEAFALAKEALTIDMKSYICWHVYGILYRTNKNFDEAIKAYKFALKLEPESHQIQRDLAV 120 Query: 394 CQKKAK 399 Q + + Sbjct: 121 LQIQMR 126 >1HH8-A nrPDB Length = 213 Score = 43.6 bits (101), Expect = 2e-04, Method: Composition-based stats. Identities = 14/74 (18%), Positives = 30/74 (40%) Query: 322 NLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEVN 381 N+ Y L+ T+A + +++ D ++RG +++ A D ++ L Sbjct: 42 NIGCMYTILKNMTEAEKAFTRSINRDKHLAVAYFQRGMLYYQTEKYDLAIKDLKEALIQL 101 Query: 382 PQNKAARLQISMCQ 395 N+ +I Q Sbjct: 102 RGNQLIDYKILGLQ 115 >2KR7-A nrPDB Length = 151 Score = 43.2 bits (100), Expect = 2e-04, Method: Composition-based stats. Identities = 16/64 (25%), Positives = 26/64 (40%) Query: 51 DKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPE 110 + Y+ + S+ EP F +G Q+I + V + GE ++ PE Sbjct: 11 QAALIEYEVREQGSSIVLDSNISKEPLEFIIGTNQIIAGLEKAVLKAQIGEWEEVVIAPE 70 Query: 111 YAYG 114 AYG Sbjct: 71 EAYG 74 Score = 30.5 bits (67), Expect = 1.8, Method: Composition-based stats. Identities = 11/43 (25%), Positives = 20/43 (46%), Gaps = 3/43 (6%) Query: 184 RDVAFTVGEGEDHDIPIGIDKALEKMQREEQCILYLGPRYGFG 226 + F +G + I G++KA+ K Q E + + P +G Sbjct: 35 EPLEFIIGTNQ---IIAGLEKAVLKAQIGEWEEVVIAPEEAYG 74 >6FUZ-A nrPDB Length = 337 Score = 43.2 bits (100), Expect = 3e-04, Method: Composition-based stats. Identities = 24/148 (16%), Positives = 53/148 (35%), Gaps = 17/148 (11%) Query: 289 IQYGKIVSWLEMEYGLSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGL-- 346 +Y + L + EK + A NLA+ Y K +Y +A C +AL + Sbjct: 69 NKYKDAANLLNDALAIREKTLGRDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIRE 128 Query: 347 ------DSANEKGLYRRGEAQLLMNEFESAKGDFEKVL-----EVNPQNKAA---RLQIS 392 K L ++E + +++ L ++ P + + ++ Sbjct: 129 KVLGKDHPDVAKQLNNLALLCQNQGKYEEVEYYYQRALGIYQTKLGPDDPNVAKTKNNLA 188 Query: 393 MCQKKAKEHNERDRRIYANMFKKFAEQD 420 C K + + + +Y + + E++ Sbjct: 189 SCYLKQGKFKQAET-LYKEILTRAHERE 215 Score = 30.5 bits (67), Expect = 1.8, Method: Composition-based stats. Identities = 20/112 (17%), Positives = 40/112 (35%), Gaps = 18/112 (16%) Query: 225 FGEAGKPKFGIEPNAELIYEVTLKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKY 284 +G+ GK K E + ++ K+ + A + + GKY Sbjct: 107 YGKRGKYK-----------EAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKY 155 Query: 285 MQAVIQYGKIVSWLEMEYGLSEKESKASESFLLAAFLNLAMCYLKLREYTKA 336 + Y + + G+ + + + + NLA CYLK ++ +A Sbjct: 156 EEVEYYYQRAL-------GIYQTKLGPDDPNVAKTKNNLASCYLKQGKFKQA 200 >3NF1-A nrPDB Length = 311 Score = 42.8 bits (99), Expect = 4e-04, Method: Composition-based stats. Identities = 25/148 (16%), Positives = 53/148 (35%), Gaps = 17/148 (11%) Query: 289 IQYGKIVSWLEMEYGLSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGL-- 346 +Y + L + EK + A NLA+ Y K +Y +A C +AL + Sbjct: 83 NKYKDAANLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIRE 142 Query: 347 ------DSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEVN-----PQNKAA---RLQIS 392 K L ++E + +++ LE+ P + + ++ Sbjct: 143 KVLGKDHPDVAKQLNNLALLCQNQGKYEEVEYYYQRALEIYQTKLGPDDPNVAKTKNNLA 202 Query: 393 MCQKKAKEHNERDRRIYANMFKKFAEQD 420 C K + + + +Y + + E++ Sbjct: 203 SCYLKQGKFKQAET-LYKEILTRAHERE 229 Score = 28.9 bits (63), Expect = 5.0, Method: Composition-based stats. Identities = 19/112 (16%), Positives = 39/112 (34%), Gaps = 18/112 (16%) Query: 225 FGEAGKPKFGIEPNAELIYEVTLKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKY 284 +G+ GK K E + ++ K+ + A + + GKY Sbjct: 121 YGKRGKYK-----------EAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKY 169 Query: 285 MQAVIQYGKIVSWLEMEYGLSEKESKASESFLLAAFLNLAMCYLKLREYTKA 336 + Y + + + + + + + NLA CYLK ++ +A Sbjct: 170 EEVEYYYQRALE-------IYQTKLGPDDPNVAKTKNNLASCYLKQGKFKQA 214 >5DSE-A nrPDB Length = 837 Score = 41.3 bits (95), Expect = 9e-04, Method: Composition-based stats. Identities = 20/110 (18%), Positives = 47/110 (42%), Gaps = 2/110 (1%) Query: 287 AVIQYGKIVSWLEMEYGLSEKESKASESF--LLAAFLNLAMCYLKLREYTKAVECCDKAL 344 A + + +S + S + + L +L+ A Y+ + + +A C +A Sbjct: 658 AASRVEQALSEVASSLQSSAPKQGPLHPWMTLAQIWLHAAEVYIGIGKPAEATACTQEAA 717 Query: 345 GLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEVNPQNKAARLQISMC 394 L + LY RG+ L + A+ +E+ L ++P + + ++++ Sbjct: 718 NLFPMSHNVLYMRGQIAELRGSMDEARRWYEEALAISPTHVKSMQRLALI 767 >3CGM-A nrPDB Length = 158 Score = 40.1 bits (92), Expect = 0.002, Method: Composition-based stats. Identities = 20/135 (14%), Positives = 43/135 (31%), Gaps = 19/135 (14%) Query: 52 KVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEY 111 V + Y ++ G+ D + G +I + + ++GE E Sbjct: 8 VVTIRYTLQVE-GEVLDQGE-----LSYLHGHRNLIPGLEEALEGREEGEAFQAHVPAEK 61 Query: 112 AYGSAGSLP-KIPSNATLFFEIELL---DFKGEDLFEDGGIIRRTKRKGEGYSNPNEGAT 167 AYG ++ + + E++ F +D+ + + +GE Sbjct: 62 AYGPHDPEGVQVVPLSAFPEDAEVVPGAQFYAQDMEGNPMPLTVVAVEGE---------E 112 Query: 168 VEIHLEGRCGGRMFD 182 V + G+ D Sbjct: 113 VTVDFNHPLAGKDLD 127 Score = 37.0 bits (84), Expect = 0.015, Method: Composition-based stats. Identities = 12/83 (14%), Positives = 31/83 (37%), Gaps = 3/83 (3%) Query: 166 ATVEIHLEGRCGGRMFDCRDVAFTVGEGEDHDIPIGIDKALEKMQREEQCILYLGPRYGF 225 V I + G + D ++++ G ++ G+++ALE + E ++ + Sbjct: 7 KVVTIRYTLQVEGEVLDQGELSYLHGH---RNLIPGLEEALEGREEGEAFQAHVPAEKAY 63 Query: 226 GEAGKPKFGIEPNAELIYEVTLK 248 G + P + + + Sbjct: 64 GPHDPEGVQVVPLSAFPEDAEVV 86 >5OJF-A nrPDB Length = 314 Score = 39.7 bits (91), Expect = 0.002, Method: Composition-based stats. Identities = 25/148 (16%), Positives = 51/148 (34%), Gaps = 17/148 (11%) Query: 289 IQYGKIVSWLEMEYGLSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGL-- 346 +Y L + EK + A NLA+ Y K +Y +A C +AL + Sbjct: 84 NKYKDAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIRE 143 Query: 347 ------DSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEVN-----PQNKAA---RLQIS 392 K L + E + + + LE+ P + + ++ Sbjct: 144 KVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYATRLGPDDPNVAKTKNNLA 203 Query: 393 MCQKKAKEHNERDRRIYANMFKKFAEQD 420 C K ++ + + +Y + + E++ Sbjct: 204 SCYLKQGKYQDAET-LYKEILTRAHEKE 230 >4I9E-A nrPDB Length = 383 Score = 39.7 bits (91), Expect = 0.003, Method: Composition-based stats. Identities = 13/89 (14%), Positives = 34/89 (38%), Gaps = 8/89 (8%) Query: 288 VIQYGKIVSWLEMEYGLSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALG-L 346 + QY +S + Y ++E E + + N+ +C +Y A+ +A+ Sbjct: 197 LKQYEDAISHFQKAYSMAEAEKQP--QLMGRTLYNIGLCKNSQSQYEDAIPYFKRAIAVF 254 Query: 347 DSAN-----EKGLYRRGEAQLLMNEFESA 370 + +N + + + + + + A Sbjct: 255 EESNILPSLPQAYFLITQIHYKLGKIDKA 283 >4I1A-A nrPDB Length = 391 Score = 39.3 bits (90), Expect = 0.003, Method: Composition-based stats. Identities = 25/151 (16%), Positives = 56/151 (37%), Gaps = 18/151 (11%) Query: 283 KYMQAVIQYGKIVSWLEMEYGLSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDK 342 +Y +A+ Q+ K + + + + +N+ +CY +L+EY KA + Sbjct: 199 EYERALEQFLKSLEISKESNIEH---------LIAMSHMNIGICYDELKEYKKASQHLIL 249 Query: 343 ALGLDSAN-----EKGLYRRGEAQLLMNEFESAKGDFEKVLEVNPQNKAARLQISMCQKK 397 AL + + K L+ + + A F K + +K+ + S K Sbjct: 250 ALEIFEKSKHSFLTKTLFTLTYVEAKQQNYNVALIYFRKGRFIA--DKSDDKEYSAKFKI 307 Query: 398 AKEH--NERDRRIYANMFKKFAEQDAKEEAN 426 + ++ + ++ N F A + + Sbjct: 308 LEGLFFSDGETQLIKNAFSYLASRKMFADVE 338 >6C95-A nrPDB Length = 866 Score = 39.3 bits (90), Expect = 0.003, Method: Composition-based stats. Identities = 23/139 (16%), Positives = 46/139 (33%), Gaps = 21/139 (15%) Query: 281 GGKYMQAVIQYGKIVSWLEMEYGLSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECC 340 KY +A+ Y + W K + L +L++ +++R+ E Sbjct: 93 DKKYDEAIKCYRNALKW-----------DKDNLQIL----RDLSLLQIQMRDLEGYRETR 137 Query: 341 DKALGLDSANEKGLYRRGEAQLLMNEFESA---KGDFEKVLEVNPQNKAARLQISMCQKK 397 + L L A A L+ ++E A +F K + +P + S Sbjct: 138 YQLLQLRPAQRASWIGYAIAYHLLEDYEMAAKILEEFRKTQQTSPDK--VDYEYSELL-L 194 Query: 398 AKEHNERDRRIYANMFKKF 416 + R+ +Y + Sbjct: 195 YQNQVLREAGLYREALEHL 213 Score = 31.2 bits (69), Expect = 0.83, Method: Composition-based stats. Identities = 36/223 (16%), Positives = 80/223 (35%), Gaps = 17/223 (7%) Query: 231 PKFGIEPNAELIYEVTLKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQ 290 P + P +++ L+ +E + + +++ E G G + Sbjct: 2 PAVSLPPKENALFKRILRCYEHKQYRNGLKFCKQILSNPKFAEHGETLAMKG---LTLNC 58 Query: 291 YGKIVSWLEMEYGLSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSAN 350 GK E+ + K+ + + L + ++Y +A++C AL D N Sbjct: 59 LGKKEEAYELVRRGLRNDLKSHVCWHVYGLLQRS-----DKKYDEAIKCYRNALKWDKDN 113 Query: 351 EKGLYRRGEAQLLMNEFESAKGDFEKVLEVNPQNKAARLQISMCQKKAKEHNERDRRIYA 410 + L Q+ M + E + ++L++ P +A+ + + H D + A Sbjct: 114 LQILRDLSLLQIQMRDLEGYRETRYQLLQLRPAQRASWIGYA-----IAYHLLEDYEMAA 168 Query: 411 NMFKKFAE----QDAKEEANKAMGKKTSEGVTNEKGTDSQAME 449 + ++F + K + + V E G +A+E Sbjct: 169 KILEEFRKTQQTSPDKVDYEYSELLLYQNQVLREAGLYREALE 211 >4HOQ-A nrPDB Length = 482 Score = 39.3 bits (90), Expect = 0.004, Method: Composition-based stats. Identities = 20/176 (11%), Positives = 48/176 (27%), Gaps = 11/176 (6%) Query: 278 YFKGGK-YMQAVIQYGKIVSWLEMEYGLSEK----ESKASESFLLAAFLN-LAMCYLKLR 331 +++ + +A+ K + L + A LK+ Sbjct: 258 FYRRKNSWNKALELLKKALEVTPTSSFLHHQMGLCYRAQMIQIKKATHNRPKGKDKLKVD 317 Query: 332 EY-TKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEVN----PQNKA 386 E + A+ A+ DS ++ +A+ F K L + Sbjct: 318 ELISSAIFHFKAAMERDSMFAFAYTDLANMYAEGGQYSNAEDIFRKALRLENITDDHKHQ 377 Query: 387 ARLQISMCQKKAKEHNERDRRIYANMFKKFAEQDAKEEANKAMGKKTSEGVTNEKG 442 Q+ ++ Y K + + A+ K +++ + + Sbjct: 378 IHYHYGRFQEFHRKSENTAIHHYLEALKVKDRSPLRTKLTSALKKLSTKRLCHNAL 433 Score = 36.3 bits (82), Expect = 0.032, Method: Composition-based stats. Identities = 30/196 (15%), Positives = 63/196 (32%), Gaps = 19/196 (9%) Query: 241 LIYEVTLKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYM---------QAVIQY 291 L Y LK K +E ++Q KE+ G Y + +Y Sbjct: 57 LAYVKHLKGQNKDALECLEQAEEIIQQEHSDKEEVRSLVTWGNYAWVYYHMDQLEEAQKY 116 Query: 292 GKIVSWLEMEYGLSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANE 351 + + + E A+ + Y KA +KAL ++ N Sbjct: 117 TGKIGNVCKKLSSPSNYK--LECPETDCEKGWALLKFGGKYYQKAKAAFEKALEVEPDNP 174 Query: 352 K-------GLYRRGEAQLLMNEFESAKGDFEKVLEVNPQNKAARLQISMCQKKAKEHNER 404 + +YR ++ + + G K + +NP N ++ +++ + E Sbjct: 175 EFNIGYAITVYRLDDSDREGSVKSFSLGPLRKAVTLNPDNSYIKVFLALKLQDVHAEAEG 234 Query: 405 DRRIYANMFKKFAEQD 420 ++ + + + Q Sbjct: 235 EK-YIEEILDQISSQP 249 Score = 33.2 bits (74), Expect = 0.28, Method: Composition-based stats. Identities = 32/159 (20%), Positives = 56/159 (35%), Gaps = 23/159 (14%) Query: 241 LIYEVTLKSFEKA--KESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWL 298 L ++ L E ++ + TK +L ++ + KG A+ + + Sbjct: 25 LKEDIDLFEVEDTIGQQLEFLTTKSRLALYNLLAYV--KHLKGQN-KDALECLEQAEEII 81 Query: 299 EMEYGLSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKA------LGLDSAN-- 350 + E+ E+ L + N A Y + + +A + K L S Sbjct: 82 QQEHSDKEEVRS------LVTWGNYAWVYYHMDQLEEAQKYTGKIGNVCKKLSSPSNYKL 135 Query: 351 --EKGLYRRGEAQLLMNE--FESAKGDFEKVLEVNPQNK 385 + +G A L ++ AK FEK LEV P N Sbjct: 136 ECPETDCEKGWALLKFGGKYYQKAKAAFEKALEVEPDNP 174 Score = 32.0 bits (71), Expect = 0.62, Method: Composition-based stats. Identities = 26/163 (15%), Positives = 51/163 (31%), Gaps = 21/163 (12%) Query: 247 LKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYG--- 303 + F+ A E M A + +Y +GG+Y A + K + + Sbjct: 324 IFHFKAAMERDSM-------FAFAYTDLANMYAEGGQYSNAEDIFRKALRLENITDDHKH 376 Query: 304 -----------LSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEK 352 K + L A L+ + + + K L ++ + + Sbjct: 377 QIHYHYGRFQEFHRKSENTAIHHYLEALKVKDRSPLRTKLTSALKKLSTKRLCHNALDVQ 436 Query: 353 GLYRRGEAQLLMNEFESAKGDFEKVLEVNPQNKAARLQISMCQ 395 L G L E A +EK +++P+N + + Sbjct: 437 SLSALGFVYKLEGEKRQAAEYYEKAQKIDPENAEFLTALCELR 479 >3ZFW-A nrPDB Length = 263 Score = 39.3 bits (90), Expect = 0.004, Method: Composition-based stats. Identities = 25/148 (16%), Positives = 51/148 (34%), Gaps = 17/148 (11%) Query: 289 IQYGKIVSWLEMEYGLSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGL-- 346 +Y L + EK + A NLA+ Y K +Y +A C +AL + Sbjct: 37 NKYKDAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIRE 96 Query: 347 ------DSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEVN-----PQNKAA---RLQIS 392 K L + E + + + LE+ P + + ++ Sbjct: 97 KVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYATRLGPDDPNVAKTKNNLA 156 Query: 393 MCQKKAKEHNERDRRIYANMFKKFAEQD 420 C K ++ + + +Y + + E++ Sbjct: 157 SCYLKQGKYQDAET-LYKEILTRAHEKE 183 >2KFW-A nrPDB Length = 196 Score = 38.6 bits (88), Expect = 0.006, Method: Composition-based stats. Identities = 13/63 (20%), Positives = 25/63 (39%), Gaps = 1/63 (1%) Query: 52 KVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEY 111 V + Y+ + +G D S + P + G G +I + + + G+ + Sbjct: 8 VVSLAYQVRTEDGVLVDESPV-SAPLDYLHGHGSLISGLETALEGHEVGDKFDVAVGAND 66 Query: 112 AYG 114 AYG Sbjct: 67 AYG 69 >2K8I-A nrPDB Length = 171 Score = 38.6 bits (88), Expect = 0.006, Method: Composition-based stats. Identities = 13/63 (20%), Positives = 25/63 (39%), Gaps = 1/63 (1%) Query: 52 KVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEY 111 V + Y+ + +G D S + P + G G +I + + + G+ + Sbjct: 8 VVSLAYQVRTEDGVLVDESPV-SAPLDYLHGHGSLISGLETALEGHEVGDKFDVAVGAND 66 Query: 112 AYG 114 AYG Sbjct: 67 AYG 69 >4GYO-A nrPDB Length = 373 Score = 38.2 bits (87), Expect = 0.007, Method: Composition-based stats. Identities = 22/123 (17%), Positives = 42/123 (34%), Gaps = 7/123 (5%) Query: 261 TKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYGLSEKESKASESFLLAAF 320 +EKLE EK FK + + Q +++ + K + Sbjct: 125 AEEKLEYVEDEIEKAEFLFKVAEVYYHIKQTYFSMNYASQALDIYTKYELYGRR-RVQCE 183 Query: 321 LNLAMCYLKLREYTKAVECCDKALG----LDSAN--EKGLYRRGEAQLLMNEFESAKGDF 374 +A + + KA+ AL L+ A Y G + + +++ A+G F Sbjct: 184 FIIAGNLTDVYHHEKALTHLCSALEHARQLEEAYMIAAAYYNVGHCKYSLGDYKEAEGYF 243 Query: 375 EKV 377 + Sbjct: 244 KTA 246 >3H4Z-A nrPDB Length = 568 Score = 38.2 bits (87), Expect = 0.007, Method: Composition-based stats. Identities = 43/209 (20%), Positives = 79/209 (37%), Gaps = 33/209 (15%) Query: 1 MTTDEGAKNNEESPTATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHY--K 58 +T + N++ P VA + + KD + ++ GE P I Y + Sbjct: 285 LTDEGLEAVNKDKPLGAVALKSYEEELAKDPRIAATMENAQKGEIMPNIPQMSAFWYAVR 344 Query: 59 GKLSNGKKFDSSHD----------RNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCK 108 + N + D +P + ++ KA D VA ++K E Sbjct: 345 TAVINAASGRQTVDAALAAAQTNAAADPIHYDKITEEINKAVDEAVAAIEKSE----TFD 400 Query: 109 PEYAYGSAGSLPKIPSNATLFFE--IELLDFKGEDLFEDGGI--IRRTKRKGEGYSNPNE 164 P K+P ++ FE I ++D KGE + + +++ KR G+ + Sbjct: 401 PM----------KVPDHSD-KFERHIGIIDLKGELDMRNIQVRGLKQMKRVGDANVKSED 449 Query: 165 GATVEIH-LEGRCGGRMFDCRDVAFTVGE 192 G V+ H L G + D+A+ +G+ Sbjct: 450 G-VVKAHLLVGVHDDVVSMEYDLAYKLGD 477 >4UZY-A nrPDB Length = 651 Score = 38.2 bits (87), Expect = 0.008, Method: Composition-based stats. Identities = 10/85 (11%), Positives = 32/85 (37%) Query: 309 SKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFE 368 + + + +K +++ +A++ L + L G +++ Sbjct: 9 QQPARPIAEGQYTQTIYTLIKEQKFAEAIQHLQYQLQNVPESRAALSLLGYCYYYTGQYD 68 Query: 369 SAKGDFEKVLEVNPQNKAARLQISM 393 A +E+++ + P N+ +L + Sbjct: 69 MASQMYEQLVTLYPSNEDYKLYYAQ 93 Score = 35.9 bits (81), Expect = 0.043, Method: Composition-based stats. Identities = 15/73 (20%), Positives = 29/73 (39%), Gaps = 15/73 (20%) Query: 273 EKGTVYFKGGKYMQAVIQYGKIVSWLEMEYGLSEKESKASESFLLAAFLNLAMCYLKLRE 332 G + FK GK+ A ++ V L + L N+A+CY K ++ Sbjct: 152 NTGCIMFKEGKFEAARQKFNDAVQALGYQPEL---------------LYNIALCYYKTKQ 196 Query: 333 YTKAVECCDKALG 345 + A++ + + Sbjct: 197 FGPALKHLAEIIE 209 >5A01-A nrPDB Length = 710 Score = 37.4 bits (85), Expect = 0.012, Method: Composition-based stats. Identities = 16/139 (11%), Positives = 35/139 (25%), Gaps = 32/139 (23%) Query: 268 AAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYGLSEKESKASESFLLAAFLNLAMCY 327 A G + A+ Y + + A NLA + Sbjct: 75 ADAYSNMGNTLKELQDVSGALQCYTRAI---------------QINPAFADAHSNLASIH 119 Query: 328 LKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEVNPQNKAA 387 +A++ AL L ++ ++ D++ Sbjct: 120 KDSGNIPEAIQSYRTALKLKPDFPDAYCNLAHCLQIVCDW----TDYD------------ 163 Query: 388 RLQISMCQKKAKEHNERDR 406 +++ E E++R Sbjct: 164 -IRMKKLVSIVTEQLEKNR 181 Score = 34.7 bits (78), Expect = 0.089, Method: Composition-based stats. Identities = 10/73 (13%), Positives = 22/73 (30%) Query: 319 AFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVL 378 + NLA + +A KAL + + + A +++ + Sbjct: 9 SLNNLANIKREQGYIEEATRLYLKALEVFPDFAAAHSNLASVLQQQGKLKEALMHYKEAI 68 Query: 379 EVNPQNKAARLQI 391 + P A + Sbjct: 69 RIQPTFADAYSNM 81 >5ZYQ-A nrPDB Length = 320 Score = 37.4 bits (85), Expect = 0.014, Method: Composition-based stats. Identities = 25/127 (19%), Positives = 43/127 (33%), Gaps = 19/127 (14%) Query: 279 FKGGKYMQAVIQYGKIVSWLEMEYGLSEKESKASESFLLAAFLNLAMCYLKLREYTKAVE 338 F Y A+ Y K + L + C++KL + KA Sbjct: 174 FNKKDYRGALAYYKKALRTNPGCPAEVR--------------LGMGHCFVKLNKLEKARL 219 Query: 339 CCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEVNPQNKAARLQISMCQKKA 398 +AL L+S L G A L +N E D + L ++ + + + +K+ Sbjct: 220 AFSRALELNSKCVGALV--GLAVLELNNKE---ADGSENLYFQSGSRFVQYKATSLEKQH 274 Query: 399 KEHNERD 405 K + Sbjct: 275 KHDLLTE 281 Score = 33.6 bits (75), Expect = 0.18, Method: Composition-based stats. Identities = 20/86 (23%), Positives = 37/86 (43%), Gaps = 3/86 (3%) Query: 317 LAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQ--LLMNEFESAKGDF 374 + A L A ++Y A+ KAL + R G + +N+ E A+ F Sbjct: 163 IPALLGKACISFNKKDYRGALAYYKKALRTNPGCP-AEVRLGMGHCFVKLNKLEKARLAF 221 Query: 375 EKVLEVNPQNKAARLQISMCQKKAKE 400 + LE+N + A + +++ + KE Sbjct: 222 SRALELNSKCVGALVGLAVLELNNKE 247 >5LVV-A nrPDB Length = 749 Score = 37.0 bits (84), Expect = 0.017, Method: Composition-based stats. Identities = 11/73 (15%), Positives = 24/73 (32%) Query: 319 AFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVL 378 + NLA + +AV KAL + + + A +++ + Sbjct: 32 SLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAI 91 Query: 379 EVNPQNKAARLQI 391 ++P A + Sbjct: 92 RISPTFADAYSNM 104 Score = 37.0 bits (84), Expect = 0.019, Method: Composition-based stats. Identities = 12/110 (10%), Positives = 24/110 (21%), Gaps = 18/110 (16%) Query: 268 AAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYGLSEKESKASESFLLAAFLNLAMCY 327 A G + A+ Y + + A NLA + Sbjct: 98 ADAYSNMGNTLKEMQDVQGALQCYTRAI---------------QINPAFADAHSNLASIH 142 Query: 328 LKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLM---NEFESAKGDF 374 +A+ AL L ++ +++ Sbjct: 143 KDSGNIPEAIASYRTALKLKPDFPDAYCNLAHCLQIVCDWTDYDERMKKL 192 >1HXV-A nrPDB Length = 113 Score = 37.0 bits (84), Expect = 0.018, Method: Composition-based stats. Identities = 21/91 (23%), Positives = 37/91 (40%), Gaps = 12/91 (13%) Query: 50 GDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICH--LLC 107 GD + + G + + KK S+ +N + ++G IK ++ G+ MK + L Sbjct: 33 GDIAIIDFTG-IVDNKKLASASAQN--YELTIGSNSFIKGFETGLIAMKVNQKKTLALTF 89 Query: 108 KPEYAYGSAGSLPKIPSNATLFFEIELLDFK 138 +Y S P + FE+ L K Sbjct: 90 PSDYHVKELQSKP-------VTFEVVLKAIK 113 >6D6S-A nrPDB Length = 443 Score = 33.6 bits (75), Expect = 0.17, Method: Composition-based stats. Identities = 16/63 (25%), Positives = 34/63 (53%), Gaps = 5/63 (7%) Query: 51 DKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEI--CHLLCK 108 D+V + + G + +G++F+ + FV ++G+G++I ++ G+ K GE + Sbjct: 173 DRVTIDFTGSV-DGEEFEGGKASD--FVLAMGQGRMIPGFEDGIKGHKAGEEFTIDVTFP 229 Query: 109 PEY 111 EY Sbjct: 230 EEY 232 >5ZR0-A nrPDB Length = 142 Score = 33.6 bits (75), Expect = 0.19, Method: Composition-based stats. Identities = 16/63 (25%), Positives = 34/63 (53%), Gaps = 5/63 (7%) Query: 51 DKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEI--CHLLCK 108 D+V + + G + +G++F+ + FV ++G+G++I ++ G+ K GE + Sbjct: 55 DRVTIDFTGSV-DGEEFEGGKASD--FVLAMGQGRMIPGFEDGIKGHKAGEEFTIDVTFP 111 Query: 109 PEY 111 EY Sbjct: 112 EEY 114 >5O09-1C nrPDB Length = 238 Score = 33.2 bits (74), Expect = 0.25, Method: Composition-based stats. Identities = 23/116 (19%), Positives = 43/116 (37%), Gaps = 14/116 (12%) Query: 282 GKYMQAVIQYGKIVSWLEMEYGLSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCD 341 G+ +A Y + + E GL E + A+ NLAM + +LR++ +A Sbjct: 89 GRMDKAAEFYELALK-ISAENGLEESDKVATIK------NNLAMIFKQLRKFERAEGYYC 141 Query: 342 KALG----LDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEVNPQNKAARLQISM 393 +AL LD R + + D ++ ++ + A R + Sbjct: 142 EALETFQRLDGEQS---ARVASVYNNLGVLYYSHMDVDRAQVMHERALAIRQNLHE 194 >6AF0-A nrPDB Length = 939 Score = 33.2 bits (74), Expect = 0.27, Method: Composition-based stats. Identities = 26/130 (20%), Positives = 43/130 (33%), Gaps = 16/130 (12%) Query: 280 KGGKYMQAVIQYGKIVSWLEMEYGLSEKESKASESFLLAAFLNLAMCYLKLREYTKAVEC 339 + Y + Y K + G+ A+ + + Y +AVE Sbjct: 673 EQRHYKHTLQSYDKHDRY--ALVGMGNLHLMAAREMRRETEQDR---QKRSAAYNRAVEF 727 Query: 340 CDKALGLDSANEKGLYRRGEAQLLM---NEFESAKGDFEKVLE------VNPQNKAARLQ 390 DKAL LD N +G A L+ ++++A F KV E V + Sbjct: 728 FDKALQLDPKN--AYAAQGIAIALVEDRKDYKNALQIFIKVRETIQDAHVYVNMGHIYAE 785 Query: 391 ISMCQKKAKE 400 + K + Sbjct: 786 LRQFSKAIES 795 >3AHY-A nrPDB Length = 473 Score = 32.8 bits (73), Expect = 0.34, Method: Composition-based stats. Identities = 13/43 (30%), Positives = 21/43 (48%), Gaps = 4/43 (9%) Query: 328 LKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESA 370 +++ Y + + A+ LD N KG + A LM+ FE A Sbjct: 395 FRVKYYNEYIRAMVTAVELDGVNVKGYF----AWSLMDNFEWA 433 >1L1P-A nrPDB Length = 106 Score = 32.4 bits (72), Expect = 0.38, Method: Composition-based stats. Identities = 16/63 (25%), Positives = 34/63 (53%), Gaps = 5/63 (7%) Query: 51 DKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEI--CHLLCK 108 D+V + + G + +G++F+ + FV ++G+G++I ++ G+ K GE + Sbjct: 19 DRVTIDFTGSV-DGEEFEGGKASD--FVLAMGQGRMIPGFEDGIKGHKAGEEFTIDVTFP 75 Query: 109 PEY 111 EY Sbjct: 76 EEY 78 >5UDI-A nrPDB Length = 479 Score = 32.4 bits (72), Expect = 0.45, Method: Composition-based stats. Identities = 25/99 (25%), Positives = 36/99 (36%), Gaps = 12/99 (12%) Query: 299 EMEYGLSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRG 358 E E + E+ + L + N A Y + +A DK + R Sbjct: 78 EAENLMQEEHDNQANVRSLVTWGNFAWMYYHMGRLAEAQTYLDKVENICKKLSNPFRYRM 137 Query: 359 EA--------QLLMN----EFESAKGDFEKVLEVNPQNK 385 E L+ +E AK FEKVLEV+P+N Sbjct: 138 ECPEIDCEEGWALLKCGGKNYERAKACFEKVLEVDPENP 176 >4G1T-A nrPDB Length = 472 Score = 32.4 bits (72), Expect = 0.48, Method: Composition-based stats. Identities = 35/179 (19%), Positives = 58/179 (32%), Gaps = 25/179 (13%) Query: 255 ESWEMDTKEKLEQAAIVKEKGTVYFKGGK-YMQAVIQ------YGKIVSWLEMEYGLSEK 307 ES E+D +E +K G + + +A+ + + ++ Sbjct: 134 ESPELDCEEGW---TRLKCGGNQNERAKVCFEKALEKKPKNPEFTSGLAIASYRLDNWPP 190 Query: 308 ESKASESFLLAAFLN---------LAMCYLKLREYTKAVECCDK----ALGLDSANEKGL 354 A + A LN LA+ K+RE + +K AL L Sbjct: 191 SQNAIDPLRQAIRLNPDNQYLKVLLALKLHKMREEGEEEGEGEKLVEEALEKAPGVTDVL 250 Query: 355 YRRGEAQLLMNEFESAKGDFEKVLEVNPQNKAARLQISMC--QKKAKEHNERDRRIYAN 411 + +E + A +K LE P N QI C K + N R+ +Y Sbjct: 251 RSAAKFYRRKDEPDKAIELLKKALEYIPNNAYLHCQIGCCYRAKVFQVMNLRENGMYGK 309 >4HOU-A nrPDB Length = 273 Score = 32.0 bits (71), Expect = 0.48, Method: Composition-based stats. Identities = 25/99 (25%), Positives = 36/99 (36%), Gaps = 12/99 (12%) Query: 299 EMEYGLSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRG 358 E E + E+ + L + N A Y + +A DK + R Sbjct: 71 EAENLMQEEHDNQANVRSLVTWGNFAWMYYHMGRLAEAQTYLDKVENICKKLSNPFRYRM 130 Query: 359 EA--------QLLMN----EFESAKGDFEKVLEVNPQNK 385 E L+ +E AK FEKVLEV+P+N Sbjct: 131 ECPEIDCEEGWALLKCGGKNYERAKACFEKVLEVDPENP 169 >1QQE-A nrPDB Length = 292 Score = 32.0 bits (71), Expect = 0.50, Method: Composition-based stats. Identities = 25/149 (16%), Positives = 46/149 (30%), Gaps = 20/149 (13%) Query: 282 GKYMQAVIQYGKIVSWLEMEYGLSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCD 341 Y +A+ Y W S + F+ A +Y +A + Sbjct: 132 HDYAKAIDCYELAGEWY---------AQDQSVALSNKCFIKCADLKALDGQYIEASDIYS 182 Query: 342 KALG------LDSANEKGLY-RRGEAQLLMNEFESAKGDFEKVLEVNPQNKAARLQISMC 394 K + L + K + ++G QL + +A ++ +P N A + + Sbjct: 183 KLIKSSMGNRLSQWSLKDYFLKKGLCQLAATDAVAAARTLQEGQSEDP-NFADSRESNFL 241 Query: 395 QKKAKEHNERDRRIYA---NMFKKFAEQD 420 + NE D + F F D Sbjct: 242 KSLIDAVNEGDSEQLSEHCKEFDNFMRLD 270 >6AHD-N nrPDB Length = 941 Score = 30.9 bits (68), Expect = 1.2, Method: Composition-based stats. Identities = 21/115 (18%), Positives = 42/115 (36%), Gaps = 5/115 (4%) Query: 345 GLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEVNPQNKAARLQISMCQ-----KKAK 399 + + + + + + A+ K E+ P+++ L+ + Q K Sbjct: 303 ETNPHHPPAWIASARLEEVTGKLQVARNLIMKGTEMCPKSEDVWLEAARLQPGDTAKAVV 362 Query: 400 EHNERDRRIYANMFKKFAEQDAKEEANKAMGKKTSEGVTNEKGTDSQAMEEEKPE 454 R ++ + AE + A K + +K E V N A+E E+PE Sbjct: 363 AQAVRHLPQSVRIYIRAAELETDIRAKKRVLRKALEHVPNSVRLWKAAVELEEPE 417 >5CTQ-A nrPDB Length = 561 Score = 30.5 bits (67), Expect = 1.4, Method: Composition-based stats. Identities = 20/112 (17%), Positives = 40/112 (35%), Gaps = 8/112 (7%) Query: 317 LAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGL-YRRGEAQLLMNEFESAKGDFE 375 A + N+ + Y L + C KAL E L M E + D++ Sbjct: 454 NAKYANMWLEYYNLERAHGDTQHCRKALHRAVQCTSDYPEHVCEVLLTMERTEGSLEDWD 513 Query: 376 KVLEVNPQNKAARLQISMCQKKAKEHNERDRRIYANMFKKFAEQDAKEEANK 427 ++ +++ ++ + E++ + +K AEQ + A K Sbjct: 514 IAVQKT------ETRLARVNEQRMKAAEKEAALVQQEEEK-AEQRKRARAEK 558 >5CTR-A nrPDB Length = 338 Score = 30.5 bits (67), Expect = 1.6, Method: Composition-based stats. Identities = 20/112 (17%), Positives = 40/112 (35%), Gaps = 8/112 (7%) Query: 317 LAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGL-YRRGEAQLLMNEFESAKGDFE 375 A + N+ + Y L + C KAL E L M E + D++ Sbjct: 231 NAKYANMWLEYYNLERAHGDTQHCRKALHRAVQCTSDYPEHVCEVLLTMERTEGSLEDWD 290 Query: 376 KVLEVNPQNKAARLQISMCQKKAKEHNERDRRIYANMFKKFAEQDAKEEANK 427 ++ +++ ++ + E++ + +K AEQ + A K Sbjct: 291 IAVQKT------ETRLARVNEQRMKAAEKEAALVQQEEEK-AEQRKRARAEK 335 >1H4S-A nrPDB Length = 477 Score = 30.5 bits (67), Expect = 1.6, Method: Composition-based stats. Identities = 18/95 (18%), Positives = 28/95 (29%), Gaps = 5/95 (5%) Query: 13 SPTATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGK--LSNGKKFDSS 70 P Q + KD + V G ++ + VH + + G KF Sbjct: 281 LPPRLAPIQVVIVPIYKDES-RERVLEAAQGLRQALLAQGLRVHLDDRDQHTPGYKFHEW 339 Query: 71 HDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHL 105 + PF LG + V + G L Sbjct: 340 ELKGVPFRVELGPKDLEGG--QAVLASRLGGKETL 372 >4KVO-A nrPDB Length = 731 Score = 30.5 bits (67), Expect = 1.7, Method: Composition-based stats. Identities = 35/231 (15%), Positives = 63/231 (27%), Gaps = 32/231 (13%) Query: 175 RCGGRMFDCRDVAFTVGEGEDHDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFG 234 FD AF G + + + ++ Y P + G + Sbjct: 525 TWADDQFDFHFFAFRKGSLRTYLDLMSWEDSV-----------YDDPSFREAAQGSIEIY 573 Query: 235 IE----PNAELIYEVTLKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQ 290 P A+ Y L FEK + +EK + K+ + K +A Sbjct: 574 FALFDLPFAK--YSPKLPDFEKLSSGEINEEEEKKIYKKLKKDLSKRLERAEKLKEADKS 631 Query: 291 YGKIVSWLEMEYGLSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSAN 350 K E + E E+ + + +A +C +K L N Sbjct: 632 RAKS----EDGMPVKYDEDPLGENLVATS-----------EPLKEAQKCLEKLLPYGDKN 676 Query: 351 EKGLYRRGEAQLLMNEFESAKGDFEKVLEVNPQNKAARLQISMCQKKAKEH 401 + + F++A E+ + QN + K Sbjct: 677 PSAYILAAQLYTRLKNFDTASKYLEQAKVILGQNDPTVISTEKFYNSIKTQ 727 >6N3Q-F nrPDB Length = 193 Score = 30.1 bits (66), Expect = 2.0, Method: Composition-based stats. Identities = 12/33 (36%), Positives = 19/33 (57%) Query: 320 FLNLAMCYLKLREYTKAVECCDKALGLDSANEK 352 F+ A C LKLR++ +A C++ L L + K Sbjct: 143 FVRKADCLLKLRQWEEARATCERGLALAPEDMK 175 >1ZU2-A nrPDB Length = 158 Score = 30.1 bits (66), Expect = 2.1, Method: Composition-based stats. Identities = 15/85 (17%), Positives = 34/85 (40%), Gaps = 11/85 (12%) Query: 334 TKAVECCDKALGLDSANEKGLYRRGEAQL-----------LMNEFESAKGDFEKVLEVNP 382 +A+ ++AL +D ++ ++ G A + F+ A F++ ++ P Sbjct: 63 QEAITKFEEALLIDPKKDEAVWCIGNAYTSFAFLTPDETEAKHNFDLATQFFQQAVDEQP 122 Query: 383 QNKAARLQISMCQKKAKEHNERDRR 407 N + M K + H E ++ Sbjct: 123 DNTHYLKSLEMTAKAPQLHAEAYKQ 147 >5LJ5-S nrPDB Length = 687 Score = 29.7 bits (65), Expect = 2.7, Method: Composition-based stats. Identities = 21/90 (23%), Positives = 36/90 (40%), Gaps = 9/90 (10%) Query: 334 TKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEVNPQNKAARLQISM 393 KA+ C KA KG E ++ + EF+ + +EK +E P + Q Sbjct: 428 GKAIGLCPKA-----KTFKGYI---ELEVKLKEFDRVRKIYEKFIEFQPSDLQIWSQYGE 479 Query: 394 CQKKAKEHNERDRRIYANMFKKFAEQDAKE 423 ++ +R R IY + ++ KE Sbjct: 480 LEENL-GDWDRVRGIYTIALDENSDFLTKE 508 >3EHU-A nrPDB Length = 476 Score = 29.7 bits (65), Expect = 2.8, Method: Composition-based stats. Identities = 12/57 (21%), Positives = 21/57 (36%) Query: 1 MTTDEGAKNNEESPTATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHY 57 +T + N++ P VA + + KD + ++ GE P I Y Sbjct: 287 LTDEGLEAVNKDKPLGAVALKSYEEELAKDPRIAATMENEQKGEIMPNIPQMSAFWY 343 >5NPF-A nrPDB Length = 798 Score = 28.9 bits (63), Expect = 4.9, Method: Composition-based stats. Identities = 18/73 (24%), Positives = 29/73 (39%), Gaps = 4/73 (5%) Query: 186 VAFTVGEGEDHDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEV 245 V F + G+ ++P + L M+ Y FG+ GK F I A Y+ Sbjct: 306 VNFKLQPGQTIEVPFALSWDLPIMKFGGGDKWYKMYTKYFGKNGKNSFAILKEALNNYQ- 364 Query: 246 TLKSFEKAKESWE 258 +EK + W+ Sbjct: 365 ---KWEKMIDDWQ 374 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.305 0.129 0.335 Lambda K H 0.267 0.0395 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 16,601,128 Number of Sequences: 36641 Number of extensions: 691540 Number of successful extensions: 2139 Number of sequences better than 10.0: 126 Number of HSP's better than 10.0 without gapping: 162 Number of HSP's successfully gapped in prelim test: 50 Number of HSP's that attempted gapping in prelim test: 1532 Number of HSP's gapped (non-prelim): 353 length of query: 457 length of database: 10,336,785 effective HSP length: 100 effective length of query: 357 effective length of database: 6,672,685 effective search space: 2382148545 effective search space used: 2382148545 T: 11 A: 40 X1: 16 ( 7.0 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.4 bits) S2: 61 (28.2 bits)