BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q13325 (482 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 4HOQ-A nrPDB 997 0.0 5UDI-A nrPDB 527 e-150 4G1T-A nrPDB 388 e-108 4HOU-A nrPDB 340 1e-93 1W3B-A nrPDB 45 9e-05 5LVV-A nrPDB 38 0.009 5A01-A nrPDB 37 0.023 2J91-A nrPDB 32 0.54 5G04-F nrPDB 32 0.55 5FZQ-A nrPDB 31 1.0 5JLD-A nrPDB 31 1.1 5MGX-E nrPDB 31 1.1 6IBP-A nrPDB 31 1.1 6B85-J nrPDB 31 1.3 5BT1-A nrPDB 31 1.5 6ICZ-I nrPDB 30 1.6 6AF0-A nrPDB 30 2.6 3W8J-A nrPDB 29 4.1 5AEM-A nrPDB 29 4.6 3VWW-A nrPDB 29 4.9 5LJ5-S nrPDB 29 5.0 2J1P-A nrPDB 29 5.7 3Q15-A nrPDB 28 6.4 3ZN3-A nrPDB 28 7.6 4D10-D nrPDB 28 7.7 >4HOQ-A nrPDB Length = 482 Score = 997 bits (2578), Expect = 0.0, Method: Compositional matrix adjust. Identities = 482/482 (100%), Positives = 482/482 (100%) Query: 1 MSEIRKDTLKAILLELECHFTWNLLKEDIDLFEVEDTIGQQLEFLTTKSRLALYNLLAYV 60 MSEIRKDTLKAILLELECHFTWNLLKEDIDLFEVEDTIGQQLEFLTTKSRLALYNLLAYV Sbjct: 1 MSEIRKDTLKAILLELECHFTWNLLKEDIDLFEVEDTIGQQLEFLTTKSRLALYNLLAYV 60 Query: 61 KHLKGQNKDALECLEQAEEIIQQEHSDKEEVRSLVTWGNYAWVYYHMDQLEEAQKYTGKI 120 KHLKGQNKDALECLEQAEEIIQQEHSDKEEVRSLVTWGNYAWVYYHMDQLEEAQKYTGKI Sbjct: 61 KHLKGQNKDALECLEQAEEIIQQEHSDKEEVRSLVTWGNYAWVYYHMDQLEEAQKYTGKI 120 Query: 121 GNVCKKLSSPSNYKLECPETDCEKGWALLKFGGKYYQKAKAAFEKALEVEPDNPEFNIGY 180 GNVCKKLSSPSNYKLECPETDCEKGWALLKFGGKYYQKAKAAFEKALEVEPDNPEFNIGY Sbjct: 121 GNVCKKLSSPSNYKLECPETDCEKGWALLKFGGKYYQKAKAAFEKALEVEPDNPEFNIGY 180 Query: 181 AITVYRLDDSDREGSVKSFSLGPLRKAVTLNPDNSYIKVFLALKLQDVHAEAEGEKYIEE 240 AITVYRLDDSDREGSVKSFSLGPLRKAVTLNPDNSYIKVFLALKLQDVHAEAEGEKYIEE Sbjct: 181 AITVYRLDDSDREGSVKSFSLGPLRKAVTLNPDNSYIKVFLALKLQDVHAEAEGEKYIEE 240 Query: 241 ILDQISSQPYVLRYAAKFYRRKNSWNKALELLKKALEVTPTSSFLHHQMGLCYRAQMIQI 300 ILDQISSQPYVLRYAAKFYRRKNSWNKALELLKKALEVTPTSSFLHHQMGLCYRAQMIQI Sbjct: 241 ILDQISSQPYVLRYAAKFYRRKNSWNKALELLKKALEVTPTSSFLHHQMGLCYRAQMIQI 300 Query: 301 KKATHNRPKGKDKLKVDELISSAIFHFKAAMERDSMFAFAYTDLANMYAEGGQYSNAEDI 360 KKATHNRPKGKDKLKVDELISSAIFHFKAAMERDSMFAFAYTDLANMYAEGGQYSNAEDI Sbjct: 301 KKATHNRPKGKDKLKVDELISSAIFHFKAAMERDSMFAFAYTDLANMYAEGGQYSNAEDI 360 Query: 361 FRKALRLENITDDHKHQIHYHYGRFQEFHRKSENTAIHHYLEALKVKDRSPLRTKLTSAL 420 FRKALRLENITDDHKHQIHYHYGRFQEFHRKSENTAIHHYLEALKVKDRSPLRTKLTSAL Sbjct: 361 FRKALRLENITDDHKHQIHYHYGRFQEFHRKSENTAIHHYLEALKVKDRSPLRTKLTSAL 420 Query: 421 KKLSTKRLCHNALDVQSLSALGFVYKLEGEKRQAAEYYEKAQKIDPENAEFLTALCELRL 480 KKLSTKRLCHNALDVQSLSALGFVYKLEGEKRQAAEYYEKAQKIDPENAEFLTALCELRL Sbjct: 421 KKLSTKRLCHNALDVQSLSALGFVYKLEGEKRQAAEYYEKAQKIDPENAEFLTALCELRL 480 Query: 481 SI 482 SI Sbjct: 481 SI 482 >5UDI-A nrPDB Length = 479 Score = 527 bits (1358), Expect = e-150, Method: Compositional matrix adjust. Identities = 257/442 (58%), Positives = 337/442 (76%), Gaps = 1/442 (0%) Query: 9 LKAILLELECHFTWNLLKEDIDLFEVEDTIGQQLEFLTTKSRLALYNLLAYVKHLKGQNK 68 +K L +L CHFTW L +D ++ ++E+ + Q+EFL TK + ++NLLAYVKHLKGQN+ Sbjct: 11 VKDSLEQLRCHFTWELSIDDDEMPDLENRVLDQIEFLDTKYSVGIHNLLAYVKHLKGQNE 70 Query: 69 DALECLEQAEEIIQQEHSDKEEVRSLVTWGNYAWVYYHMDQLEEAQKYTGKIGNVCKKLS 128 +AL+ L++AE ++Q+EH ++ VRSLVTWGN+AW+YYHM +L EAQ Y K+ N+CKKLS Sbjct: 71 EALKSLKEAENLMQEEHDNQANVRSLVTWGNFAWMYYHMGRLAEAQTYLDKVENICKKLS 130 Query: 129 SPSNYKLECPETDCEKGWALLKFGGKYYQKAKAAFEKALEVEPDNPEFNIGYAITVYRLD 188 +P Y++ECPE DCE+GWALLK GGK Y++AKA FEK LEV+P+NPE + GYAI+ YRLD Sbjct: 131 NPFRYRMECPEIDCEEGWALLKCGGKNYERAKACFEKVLEVDPENPESSAGYAISAYRLD 190 Query: 189 DSD-REGSVKSFSLGPLRKAVTLNPDNSYIKVFLALKLQDVHAEAEGEKYIEEILDQISS 247 + K FSL PLR+AV LNPDN YIKV LALKLQD EAEGEKYIEE L +SS Sbjct: 191 GFKLATKNHKPFSLLPLRQAVRLNPDNGYIKVLLALKLQDEGQEAEGEKYIEEALANMSS 250 Query: 248 QPYVLRYAAKFYRRKNSWNKALELLKKALEVTPTSSFLHHQMGLCYRAQMIQIKKATHNR 307 Q YV RYAAKFYRRK S +KALELLKKAL+ TPTS LHHQ+GLCY+AQMIQIK+AT + Sbjct: 251 QTYVFRYAAKFYRRKGSVDKALELLKKALQETPTSVLLHHQIGLCYKAQMIQIKEATKGQ 310 Query: 308 PKGKDKLKVDELISSAIFHFKAAMERDSMFAFAYTDLANMYAEGGQYSNAEDIFRKALRL 367 P+G+++ K+D++I SAIFHF++A+E+ F A+ DLA MY E G + AE+ F+K L + Sbjct: 311 PRGQNREKLDKMIRSAIFHFESAVEKKPTFEVAHLDLARMYIEAGNHRKAEENFQKLLCM 370 Query: 368 ENITDDHKHQIHYHYGRFQEFHRKSENTAIHHYLEALKVKDRSPLRTKLTSALKKLSTKR 427 + + ++ IH+HYGRFQEF +KS+ AI HYL+A+K++ S R K ++LKKL ++ Sbjct: 371 KPVVEETMQDIHFHYGRFQEFQKKSDVNAIIHYLKAIKIEQASLTRDKSINSLKKLVLRK 430 Query: 428 LCHNALDVQSLSALGFVYKLEG 449 L ALD++SLS LGFVYKLEG Sbjct: 431 LRRKALDLESLSLLGFVYKLEG 452 >4G1T-A nrPDB Length = 472 Score = 388 bits (997), Expect = e-108, Method: Compositional matrix adjust. Identities = 215/465 (46%), Positives = 297/465 (63%), Gaps = 13/465 (2%) Query: 1 MSEIRKDTLKAILLELECHFTWNLLKEDIDLFEVEDTIGQQLEFLTTKSRLALYNLLAYV 60 MSE K++L++ L +L+CHFTWNL++ + L + ED + + EF + + + NLLAY+ Sbjct: 1 MSENNKNSLESSLRQLKCHFTWNLMEGENSLDDFEDKVFYRTEFQNREFKATMCNLLAYL 60 Query: 61 KHLKGQNKDALECLEQAEEIIQQEHSDKEEVRSLVTWGNYAWVYYHMDQLEEAQKYTGKI 120 KHLKGQN+ ALECL +AEE+IQQEH+D+ E+RSLVTWGNYAWVYYHM +L + Q Y K+ Sbjct: 61 KHLKGQNEAALECLRKAEELIQQEHADQAEIRSLVTWGNYAWVYYHMGRLSDVQIYVDKV 120 Query: 121 GNVCKKLSSPSNYKLECPETDCEKGWALLKFGGKYYQKAKAAFEKALEVEPDNPEFNIGY 180 +VC+K SSP Y++E PE DCE+GW LK GG ++AK FEKALE +P NPEF G Sbjct: 121 KHVCEKFSSP--YRIESPELDCEEGWTRLKCGGNQNERAKVCFEKALEKKPKNPEFTSGL 178 Query: 181 AITVYRLDDSDREGSVKSFSLGPLRKAVTLNPDNSYIKVFLALKLQDVH----AEAEGEK 236 AI YRLD+ + ++ PLR+A+ LNPDN Y+KV LALKL + E EGEK Sbjct: 179 AIASYRLDNWPPSQN----AIDPLRQAIRLNPDNQYLKVLLALKLHKMREEGEEEGEGEK 234 Query: 237 YIEEILDQISSQPYVLRYAAKFYRRKNSWNKALELLKKALEVTPTSSFLHHQMGLCYRAQ 296 +EE L++ VLR AAKFYRRK+ +KA+ELLKKALE P +++LH Q+G CYRA+ Sbjct: 235 LVEEALEKAPGVTDVLRSAAKFYRRKDEPDKAIELLKKALEYIPNNAYLHCQIGCCYRAK 294 Query: 297 MIQIKKATHNRPKGKDKLKVDELISSAIFHFKAAMERDSMFAFAYTDLANMYAEGGQYSN 356 + Q+ N GK KL ELI A+ H K A E + + LA+++A QY Sbjct: 295 VFQVMNLRENGMYGKRKLL--ELIGHAVAHLKKADEANDNLFRVCSILASLHALADQYEE 352 Query: 357 AEDIFRKALRLENITDDHKHQIHYHYGRFQEFHRKSENTAIHHYLEALKVKDRSPLRTKL 416 AE F+K E +T K +H YG FQ + K E+ AIHH++E +K+ +S + K+ Sbjct: 353 AEYYFQKEFSKE-LTPVAKQLLHLRYGNFQLYQMKCEDKAIHHFIEGVKINQKSREKEKM 411 Query: 417 TSALKKLSTKRLCHNALDVQSLSALGFVYKLEGEKRQAAEYYEKA 461 L+K++ RL N D ++L L F+ +L + +QA E E+ Sbjct: 412 KDKLQKIAKMRLSKNGADSEALHVLAFLQELNEKMQQADEDSERG 456 >4HOU-A nrPDB Length = 273 Score = 340 bits (871), Expect = 1e-93, Method: Compositional matrix adjust. Identities = 167/270 (61%), Positives = 210/270 (77%), Gaps = 1/270 (0%) Query: 9 LKAILLELECHFTWNLLKEDIDLFEVEDTIGQQLEFLTTKSRLALYNLLAYVKHLKGQNK 68 +K L +L CHFTW L +D ++ ++E+ + Q+EFL TK + ++NLLAYVKHLKGQN+ Sbjct: 4 VKDSLEQLRCHFTWELSIDDDEMPDLENRVLDQIEFLDTKYSVGIHNLLAYVKHLKGQNE 63 Query: 69 DALECLEQAEEIIQQEHSDKEEVRSLVTWGNYAWVYYHMDQLEEAQKYTGKIGNVCKKLS 128 +AL+ L++AE ++Q+EH ++ VRSLVTWGN+AW+YYHM +L EAQ Y K+ N+CKKLS Sbjct: 64 EALKSLKEAENLMQEEHDNQANVRSLVTWGNFAWMYYHMGRLAEAQTYLDKVENICKKLS 123 Query: 129 SPSNYKLECPETDCEKGWALLKFGGKYYQKAKAAFEKALEVEPDNPEFNIGYAITVYRLD 188 +P Y++ECPE DCE+GWALLK GGK Y++AKA FEK LEV+P+NPE + GYAI+ YRLD Sbjct: 124 NPFRYRMECPEIDCEEGWALLKCGGKNYERAKACFEKVLEVDPENPESSAGYAISAYRLD 183 Query: 189 DSD-REGSVKSFSLGPLRKAVTLNPDNSYIKVFLALKLQDVHAEAEGEKYIEEILDQISS 247 + K FSL PLR+AV LNPDN YIKV LALKLQD EAEGEKYIEE L +SS Sbjct: 184 GFKLATKNHKPFSLLPLRQAVRLNPDNGYIKVLLALKLQDEGQEAEGEKYIEEALANMSS 243 Query: 248 QPYVLRYAAKFYRRKNSWNKALELLKKALE 277 Q YV RYAAKFYRRK S +KALELLKKAL+ Sbjct: 244 QTYVFRYAAKFYRRKGSVDKALELLKKALQ 273 >1W3B-A nrPDB Length = 388 Score = 44.7 bits (104), Expect = 9e-05, Method: Compositional matrix adjust. Identities = 48/164 (29%), Positives = 78/164 (47%), Gaps = 19/164 (11%) Query: 326 HFKA-AMERDSMFAFAYTDLANMYAEGGQYSNAEDIFRKALRLENITDDHKHQIHYHYGR 384 HF A++++ + A AY++L N+Y E GQ A + +R ALRL+ D + Sbjct: 54 HFSTLAIKQNPLLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVA 113 Query: 385 FQEFHRKSENTAIHHYLEALKVK-DRSPLRTKLTS---ALKKLSTKRLCH-NALDVQ--- 436 + A+ Y+ AL+ D +R+ L + AL +L + C+ A++ Q Sbjct: 114 AGDME-----GAVQAYVSALQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQPNF 168 Query: 437 --SLSALGFVYKLEGEKRQAAEYYEKAQKIDPENAEFLTALCEL 478 + S LG V+ +GE A ++EKA +DP FL A L Sbjct: 169 AVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDP---NFLDAYINL 209 Score = 43.5 bits (101), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 46/198 (23%), Positives = 81/198 (40%), Gaps = 28/198 (14%) Query: 153 GKYYQKAKAAFEKALEVEPDNPEFNIGYAITVYRLDDSDREGSVKSFSLGPLRKAVTLNP 212 + + +A AA+ +AL + P++ + A Y E + ++ R+A+ L P Sbjct: 216 ARIFDRAVAAYLRALSLSPNHAVVHGNLACVYY-------EQGLIDLAIDTYRRAIELQP 268 Query: 213 DNSYIKVFLALKLQDVHAEAEGEKYIEEILDQISSQPYVLRYAAKFYRRKNSWNKALELL 272 LA L++ + AE E L + L A R + + +A+ L Sbjct: 269 HFPDAYCNLANALKEKGSVAEAEDCYNTALRLCPTHADSLNNLANIKREQGNIEEAVRLY 328 Query: 273 KKALEVTPTSSFLHHQMGLCYRAQMIQIKKATHNRPKGKDKLKVDELISSAIFHFKAAME 332 +KALEV P + H + A ++Q +GK + A+ H+K A+ Sbjct: 329 RKALEVFPEFAAAHSNL-----ASVLQ--------QQGK--------LQEALMHYKEAIR 367 Query: 333 RDSMFAFAYTDLANMYAE 350 FA AY+++ N E Sbjct: 368 ISPTFADAYSNMGNTLKE 385 Score = 40.8 bits (94), Expect = 0.001, Method: Compositional matrix adjust. Identities = 57/236 (24%), Positives = 88/236 (37%), Gaps = 66/236 (27%) Query: 132 NYKLECPETDCEKGWALLKFGGKYYQKAKAAFEKALEVEPDNPEFNIGYAITVYRLDDSD 191 N L C +D LLK G+ ++AKA + KA+E +P+ +A+ L Sbjct: 131 NPDLYCVRSDLGN---LLKALGRL-EEAKACYLKAIETQPN-------FAVAWSNLGCVF 179 Query: 192 REGSVKSFSLGPLRKAVTLNPDNSYIKVFLALKLQDVHAEAEGEKYIEEILDQISSQPYV 251 ++ KAVTL+P+ LD + V Sbjct: 180 NAQGEIWLAIHHFEKAVTLDPN---------------------------FLDAYINLGNV 212 Query: 252 LRYAAKFYRRKNSWNKALELLKKALEVTPTSSFLHHQMGLCYRAQMIQIKKATHNRPKGK 311 L+ A F ++A+ +AL ++P + +H + Y Q Sbjct: 213 LKEARIF-------DRAVAAYLRALSLSPNHAVVHGNLACVYYEQ--------------- 250 Query: 312 DKLKVDELISSAIFHFKAAMERDSMFAFAYTDLANMYAEGGQYSNAEDIFRKALRL 367 LI AI ++ A+E F AY +LAN E G + AED + ALRL Sbjct: 251 ------GLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGSVAEAEDCYNTALRL 300 >5LVV-A nrPDB Length = 749 Score = 38.1 bits (87), Expect = 0.009, Method: Compositional matrix adjust. Identities = 41/163 (25%), Positives = 63/163 (38%), Gaps = 32/163 (19%) Query: 252 LRYAAKFYRRKNSWNKALELLKKALEVTPTSSFLHHQMGLCYRAQMIQIKKATHNRPKGK 311 L A R + + +A+ L +KALEV P + H + + Q GK Sbjct: 33 LNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQ-------------GK 79 Query: 312 DKLKVDELISSAIFHFKAAMERDSMFAFAYTDLANMYAEGGQYSNAEDIFRKALRLEN-I 370 + A+ H+K A+ FA AY+++ N E A + +A+++ Sbjct: 80 --------LQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAF 131 Query: 371 TDDHKH--QIHYHYGRFQEFHRKSENTAIHHYLEALKVKDRSP 411 D H + IH G E AI Y ALK+K P Sbjct: 132 ADAHSNLASIHKDSGNIPE--------AIASYRTALKLKPDFP 166 Score = 29.3 bits (64), Expect = 4.1, Method: Compositional matrix adjust. Identities = 37/154 (24%), Positives = 64/154 (41%), Gaps = 24/154 (15%) Query: 338 AFAYTDLANMYAEGGQYSNAEDIFRKALRL-ENITDDHKH--QIHYHYGRFQEFHRKSEN 394 A + +LAN+ E G A ++RKAL + H + + G+ QE Sbjct: 30 ADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQE------- 82 Query: 395 TAIHHYLEALKVKDR-SPLRTKLTSALKKLS---------TKRLCHNALDVQSLSALGFV 444 A+ HY EA+++ + + + + LK++ T+ + N + S L + Sbjct: 83 -ALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASI 141 Query: 445 YKLEGEKRQAAEYYEKAQKIDPENAEFLTALCEL 478 +K G +A Y A K+ P +F A C L Sbjct: 142 HKDSGNIPEAIASYRTALKLKP---DFPDAYCNL 172 >5A01-A nrPDB Length = 710 Score = 36.6 bits (83), Expect = 0.023, Method: Compositional matrix adjust. Identities = 43/163 (26%), Positives = 61/163 (37%), Gaps = 32/163 (19%) Query: 252 LRYAAKFYRRKNSWNKALELLKKALEVTPTSSFLHHQMGLCYRAQMIQIKKATHNRPKGK 311 L A R + +A L KALEV P + H + + Q Sbjct: 10 LNNLANIKREQGYIEEATRLYLKALEVFPDFAAAHSNLASVLQQQ--------------- 54 Query: 312 DKLKVDELISSAIFHFKAAMERDSMFAFAYTDLANMYAEGGQYSNAEDIFRKALRLEN-I 370 KLK A+ H+K A+ FA AY+++ N E S A + +A+++ Sbjct: 55 GKLK------EALMHYKEAIRIQPTFADAYSNMGNTLKELQDVSGALQCYTRAIQINPAF 108 Query: 371 TDDHKH--QIHYHYGRFQEFHRKSENTAIHHYLEALKVKDRSP 411 D H + IH G E AI Y ALK+K P Sbjct: 109 ADAHSNLASIHKDSGNIPE--------AIQSYRTALKLKPDFP 143 >2J91-A nrPDB Length = 503 Score = 32.0 bits (71), Expect = 0.54, Method: Compositional matrix adjust. Identities = 22/109 (20%), Positives = 48/109 (44%), Gaps = 10/109 (9%) Query: 34 VEDTIGQQLEFLTTKSRLALYNLLAYVKHLKGQNKDALECL----EQAEEIIQQEHSDKE 89 +E I Q+L F+ T+ N++ + G +D E + +QA +++QE D + Sbjct: 391 IERRIRQELPFMATE------NIIMAMVKAGGSRQDCHEKIRVLSQQAASVVKQEGGDND 444 Query: 90 EVRSLVTWGNYAWVYYHMDQLEEAQKYTGKIGNVCKKLSSPSNYKLECP 138 + + ++ ++ +D L + +TG+ ++ Y L P Sbjct: 445 LIERIQVDAYFSPIHSQLDHLLDPSSFTGRASQQVQRFLEEEVYPLLKP 493 >5G04-F nrPDB Length = 824 Score = 32.0 bits (71), Expect = 0.55, Method: Compositional matrix adjust. Identities = 38/149 (25%), Positives = 65/149 (43%), Gaps = 35/149 (23%) Query: 323 AIFHFKAAMERDSMFAFAYTDLANMYAEGGQYSNAEDIFRKALRLENITDDHKHQIHYH- 381 AI F+ A++ D +A+AYT L + + + A FR A+R+ + HY+ Sbjct: 586 AIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRV--------NPRHYNA 637 Query: 382 -YGRFQEFHRKSE-NTAIHHYLEALKVKDRSPLRTKLTSALKKLSTKRLCHNALDVQSLS 439 YG ++++ + + A H+ +AL + +S S L LCH Sbjct: 638 WYGLGMIYYKQEKFSLAEMHFQKALDINPQS-------SVL-------LCH--------- 674 Query: 440 ALGFVYKLEGEKRQAAEYYEKAQKIDPEN 468 +G V + +A + KA IDP+N Sbjct: 675 -IGVVQHALKKSEKALDTLNKAIVIDPKN 702 >5FZQ-A nrPDB Length = 131 Score = 31.2 bits (69), Expect = 1.0, Method: Compositional matrix adjust. Identities = 15/45 (33%), Positives = 25/45 (55%) Query: 434 DVQSLSALGFVYKLEGEKRQAAEYYEKAQKIDPENAEFLTALCEL 478 +++LS L + EG+ +A +Y KA +DP N + L+ L L Sbjct: 4 SIKTLSNLANLLAQEGKAEEAIKYMRKAVSLDPNNIKTLSNLANL 48 Score = 31.2 bits (69), Expect = 1.2, Method: Compositional matrix adjust. Identities = 15/45 (33%), Positives = 26/45 (57%) Query: 434 DVQSLSALGFVYKLEGEKRQAAEYYEKAQKIDPENAEFLTALCEL 478 ++++LS L + EG+ +A +Y KA +DP N + L+ L L Sbjct: 38 NIKTLSNLANLLAQEGKAEEAIKYMRKAVSLDPNNIKTLSNLAVL 82 >5JLD-A nrPDB Length = 599 Score = 31.2 bits (69), Expect = 1.1, Method: Compositional matrix adjust. Identities = 20/63 (31%), Positives = 33/63 (52%), Gaps = 6/63 (9%) Query: 317 DELISSAIFHFKAAMERDSMFAFAYTDLANMYAEGG-----QYSNAEDIFRKA-LRLENI 370 + L SAI +F R+S + F+Y ++ N+ G YS IFRK+ + +E+I Sbjct: 441 ESLCVSAIKYFDLKQHRNSDYKFSYDNMLNVKGNTGIYIIYGYSRICSIFRKSTINVEDI 500 Query: 371 TDD 373 + D Sbjct: 501 SKD 503 >5MGX-E nrPDB Length = 290 Score = 31.2 bits (69), Expect = 1.1, Method: Compositional matrix adjust. Identities = 39/163 (23%), Positives = 63/163 (38%), Gaps = 29/163 (17%) Query: 256 AKFYRRKNSWNKALELLKKALEVTPTSSFLHHQMGLCYRAQMIQIKKATHNRPKGKDKLK 315 A F NS++ A++ + + +V M AQ++Q+K N +LK Sbjct: 145 ADFVLAANSYDLAIKAITSSAKV---------DMTFEEEAQLLQLKVKCLNN-LAASQLK 194 Query: 316 VDELISSAIFHFKAAMERDSMFAFAYTD-------LANMYAEGGQYSNAEDIFRKALRLE 368 +D H++AA+ S+ D + A+ G+YS A I R AL+LE Sbjct: 195 LD--------HYRAALRSCSLVLEHQPDNIKALFRKGKVLAQQGEYSEAIPILRAALKLE 246 Query: 369 NITDDHKHQIHYHYGRFQEFHRKSENTAIHHYLEALKVKDRSP 411 IH + + H +T Y + L R P Sbjct: 247 ----PSNKTIHAELSKLVKKHAAQRSTETALYRKMLGNPSRLP 285 >6IBP-A nrPDB Length = 420 Score = 31.2 bits (69), Expect = 1.1, Method: Compositional matrix adjust. Identities = 19/67 (28%), Positives = 33/67 (49%), Gaps = 9/67 (13%) Query: 90 EVRSLVTWGNYAWVYYHMDQLEEAQKYTGK---IGNVCKKLSSPSNYKLECPETDCEKGW 146 E+ +L TW + + Y + QLE A + TGK + + ++L S +L GW Sbjct: 318 ELTALNTWDQWTFYKYTLKQLEMASRVTGKKKDLAAIKRQLPIQSRSELAV------DGW 371 Query: 147 ALLKFGG 153 L+++ G Sbjct: 372 DLIEWSG 378 >6B85-J nrPDB Length = 223 Score = 30.8 bits (68), Expect = 1.3, Method: Compositional matrix adjust. Identities = 46/198 (23%), Positives = 83/198 (41%), Gaps = 30/198 (15%) Query: 208 VTLNPDNSYIKVFLALKLQDVHA---------EAEGEKYIEEILDQISSQPYVLRYAAKF 258 +T NPD S I L+++L + + E+ E I +S+ YV+ Sbjct: 33 ITTNPDTSQIATLLSMQLLLIALMLVVIALLLSRQTEQVAESIRRDVSALAYVMLGLLLS 92 Query: 259 YRRKNSWNKALELLKKALEVTPTSSFLHHQMGLCY--------------RAQMIQIKKAT 304 + S A E KKA+E+ P + +G +A ++ A+ Sbjct: 93 LLNRLS--LAAEAYKKAIELDPNDALAWLLLGSVLEKLKRLDEAAEAYKKAIELKPNDAS 150 Query: 305 HNRPKGKDKLKVDELISSAIFHFKAAMERDSMFAFAYTDLANMYAEGGQYSNAEDIFRKA 364 + GK K+ L A +K A+E D A A+ +L + + G+ A + ++KA Sbjct: 151 AWKELGKVLEKLGRL-DEAAEAYKKAIELDPEDAEAWKELGKVLEKLGRLDEAAEAYKKA 209 Query: 365 LRLENITDDHKHQIHYHY 382 + L+ +D +H H+H+ Sbjct: 210 IELD--PNDLEH--HHHH 223 Score = 30.0 bits (66), Expect = 2.1, Method: Compositional matrix adjust. Identities = 16/37 (43%), Positives = 23/37 (62%) Query: 434 DVQSLSALGFVYKLEGEKRQAAEYYEKAQKIDPENAE 470 D + LG V + G +AAE Y+KA ++DPE+AE Sbjct: 148 DASAWKELGKVLEKLGRLDEAAEAYKKAIELDPEDAE 184 >5BT1-A nrPDB Length = 393 Score = 30.8 bits (68), Expect = 1.5, Method: Compositional matrix adjust. Identities = 22/68 (32%), Positives = 37/68 (54%), Gaps = 10/68 (14%) Query: 347 MYAEGGQYSNAEDIFRKALRL--------ENITDDHKHQIHYHYGRFQEFHRKSE--NTA 396 +Y E Y NA D+ +AL L +++T++ + +I Y + R++E + A Sbjct: 196 IYFENDLYENALDLLAQALMLLGRPTADGQSLTENSRLRIGDVYILMGDIEREAEMFSRA 255 Query: 397 IHHYLEAL 404 IHHYL+AL Sbjct: 256 IHHYLKAL 263 >6ICZ-I nrPDB Length = 855 Score = 30.4 bits (67), Expect = 1.6, Method: Compositional matrix adjust. Identities = 19/80 (23%), Positives = 33/80 (41%), Gaps = 7/80 (8%) Query: 308 PKGKDKLKVDELISSAIFHFKAAMERDSMFAFAYTDLANMYAEGGQYSNAEDIFRKALRL 367 P L VD +I + F + + + LA+ Y G + A D++ +A+R Sbjct: 232 PDKVQSLNVDAIIRGGLTRFTDQLGK------LWCSLADYYIRSGHFEKARDVYEEAIRT 285 Query: 368 ENITDDHKHQIHYHYGRFQE 387 D Q+ Y +F+E Sbjct: 286 VMTVRDFT-QVFDSYAQFEE 304 >6AF0-A nrPDB Length = 939 Score = 30.0 bits (66), Expect = 2.6, Method: Compositional matrix adjust. Identities = 29/114 (25%), Positives = 51/114 (44%), Gaps = 21/114 (18%) Query: 260 RRKNSWNKALELLKKALEVTPTSSFLHHQMGLCYRAQMIQIKKATHNRPKGKDKLKVDEL 319 +R ++N+A+E KAL++ P ++ Y AQ I I +R K+ L++ Sbjct: 716 KRSAAYNRAVEFFDKALQLDPKNA---------YAAQGIAIA-LVEDRKDYKNALQIFIK 765 Query: 320 ISSAIFHFKAAMERDSMFAFAYTDLANMYAEGGQYSNAEDIFRKALRLENITDD 373 + I A Y ++ ++YAE Q+S A + + AL E +D Sbjct: 766 VRETI-----------QDAHVYVNMGHIYAELRQFSKAIESYEIALSKEGKAND 808 >3W8J-A nrPDB Length = 142 Score = 29.3 bits (64), Expect = 4.1, Method: Composition-based stats. Identities = 21/80 (26%), Positives = 32/80 (40%), Gaps = 3/80 (3%) Query: 260 RRKNSWNKALELLKKALEVTPTSSFLHHQMGLCYRAQ---MIQIKKATHNRPKGKDKLKV 316 R W KA LK ++V + HH +G Y Q I+I + NRP+ + Sbjct: 62 RLTPEWKKAATALKDVVKVGAVDADKHHSLGGQYGVQGFPTIKIFGSNKNRPEDYQGGRT 121 Query: 317 DELISSAIFHFKAAMERDSM 336 E I A + +D + Sbjct: 122 GEAIVDAALSALRQLVKDRL 141 >5AEM-A nrPDB Length = 447 Score = 28.9 bits (63), Expect = 4.6, Method: Compositional matrix adjust. Identities = 13/36 (36%), Positives = 22/36 (61%) Query: 156 YQKAKAAFEKALEVEPDNPEFNIGYAITVYRLDDSD 191 Y+ AK +E A++ EPD+ + + A YRL+D + Sbjct: 399 YETAKEFYELAIKSEPDDLDIRVSLAEVYYRLNDPE 434 >3VWW-A nrPDB Length = 116 Score = 28.9 bits (63), Expect = 4.9, Method: Composition-based stats. Identities = 20/67 (29%), Positives = 28/67 (41%), Gaps = 3/67 (4%) Query: 260 RRKNSWNKALELLKKALEVTPTSSFLHHQMGLCYRAQ---MIQIKKATHNRPKGKDKLKV 316 R W KA LK ++V + HH +G Y Q I+I + NRP+ + Sbjct: 36 RLTPEWKKAATALKDVVKVGAVDADKHHSLGGQYGVQGFPTIKIFGSNKNRPEDYQGGRT 95 Query: 317 DELISSA 323 E I A Sbjct: 96 GEAIVDA 102 >5LJ5-S nrPDB Length = 687 Score = 28.9 bits (63), Expect = 5.0, Method: Compositional matrix adjust. Identities = 16/65 (24%), Positives = 30/65 (46%) Query: 137 CPETDCEKGWALLKFGGKYYQKAKAAFEKALEVEPDNPEFNIGYAITVYRLDDSDREGSV 196 CP+ KG+ L+ K + + + +EK +E +P + + Y L D DR + Sbjct: 434 CPKAKTFKGYIELEVKLKEFDRVRKIYEKFIEFQPSDLQIWSQYGELEENLGDWDRVRGI 493 Query: 197 KSFSL 201 + +L Sbjct: 494 YTIAL 498 >2J1P-A nrPDB Length = 293 Score = 28.9 bits (63), Expect = 5.7, Method: Compositional matrix adjust. Identities = 31/113 (27%), Positives = 50/113 (44%), Gaps = 7/113 (6%) Query: 275 ALEVTPTSSFLHHQMGLCYRAQMIQIKKATHNRPKGKDK--LKVDELISSAIFHFKAAME 332 A+E+ T S +H + C ++ K T+++ G+D L D L+S A H +A Sbjct: 80 AVEMIHTMSLIHDDLP-CMDNDDLRRGKPTNHKVYGEDVAVLAGDALLSFAFEHLASATS 138 Query: 333 RD---SMFAFAYTDLAN-MYAEGGQYSNAEDIFRKALRLENITDDHKHQIHYH 381 + + A +LA + EG DI + L L N+ +H IH H Sbjct: 139 SEVSPARVVRAVGELAKAIGTEGLVAGQVVDISSEGLDLNNVGLEHLKFIHLH 191 >3Q15-A nrPDB Length = 378 Score = 28.5 bits (62), Expect = 6.4, Method: Compositional matrix adjust. Identities = 48/209 (22%), Positives = 88/209 (42%), Gaps = 40/209 (19%) Query: 291 LCYRAQM----IQIKKATHNRPKGKDKLKVDELISSAIFHFKAAMERDSMFAFAYTDLAN 346 +C+R Q+ ++ K NRP + L E I + ++ S+F Sbjct: 58 MCFRHQLMLDYLEPGKTYGNRPTVTELL---ETIETPQKKLTGLLKYYSLF------FRG 108 Query: 347 MYA-EGGQYSNAEDIFRKALR-LENITDD-HKHQIHYHYGRFQEFHRKSENTAIHHYLEA 403 MY + +Y A +R+A + L ++DD K + H+ +H K + +++H L+A Sbjct: 109 MYEFDQKEYVEAIGYYREAEKELPFVSDDIEKAEFHFKVAE-AYYHMKQTHVSMYHILQA 167 Query: 404 LKVKDRSPLRT-KLTSALKKLS---------TKRLCH------NALDVQ-------SLSA 440 L + PL + + +L ++ K L H A+D+Q SL Sbjct: 168 LDIYQNHPLYSIRTIQSLFVIAGNYDDFKHYDKALPHLEAALELAMDIQNDRFIAISLLN 227 Query: 441 LGFVYKLEGEKRQAAEYYEKAQKIDPENA 469 + Y G+ + A E+++KA K+ E Sbjct: 228 IANSYDRSGDDQMAVEHFQKAAKVSREKV 256 >3ZN3-A nrPDB Length = 291 Score = 28.5 bits (62), Expect = 7.6, Method: Compositional matrix adjust. Identities = 15/48 (31%), Positives = 26/48 (54%), Gaps = 4/48 (8%) Query: 237 YIEEILDQISSQ----PYVLRYAAKFYRRKNSWNKALELLKKALEVTP 280 YI E+L+ + Q PY+L + YR++ +KA++ LK + P Sbjct: 140 YISEVLESLHYQGNKDPYLLYLSGVVYRKRKQDSKAIDFLKSCVLKAP 187 >4D10-D nrPDB Length = 410 Score = 28.1 bits (61), Expect = 7.7, Method: Compositional matrix adjust. Identities = 17/53 (32%), Positives = 26/53 (49%), Gaps = 2/53 (3%) Query: 341 YTDLANMYAEGGQYSNAEDIFRKALRLENITDDHKHQIHYH--YGRFQEFHRK 391 Y +A +Y E AE +A L+N + + + QIHY Y R ++ RK Sbjct: 152 YLKIARLYLEDDDPVQAEAYINRASLLQNESTNEQLQIHYKVCYARVLDYRRK 204 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 4HOQ-A nrPDB 691 0.0 5UDI-A nrPDB 647 0.0 4G1T-A nrPDB 593 e-170 4HOU-A nrPDB 427 e-120 1W3B-A nrPDB 195 4e-50 Sequences not found previously or not previously below threshold: 5A01-A nrPDB 105 4e-23 5LVV-A nrPDB 81 8e-16 5G04-F nrPDB 61 1e-09 6B85-J nrPDB 57 1e-08 5G05-C nrPDB 51 8e-07 2GW1-A nrPDB 48 8e-06 5FZQ-A nrPDB 47 1e-05 6FO1-G nrPDB 45 8e-05 3JCM-G nrPDB 44 1e-04 5OJF-A nrPDB 43 2e-04 6FUZ-A nrPDB 42 4e-04 6AF0-A nrPDB 42 5e-04 5OJ8-A nrPDB 42 7e-04 5NNP-A nrPDB 41 9e-04 3ZFW-A nrPDB 41 9e-04 3NF1-A nrPDB 41 0.001 6MFV-A nrPDB 40 0.002 5JZ6-A nrPDB 39 0.005 4JHR-A nrPDB 39 0.005 5MGX-E nrPDB 38 0.010 5LJ5-S nrPDB 38 0.012 5JJT-A nrPDB 36 0.029 5DSE-A nrPDB 36 0.037 4KVO-A nrPDB 36 0.047 5G04-X nrPDB 36 0.059 5KHR-J nrPDB 35 0.067 5WQL-B nrPDB 35 0.078 4H7X-A nrPDB 34 0.15 4B94-A nrPDB 34 0.15 4ABN-A nrPDB 34 0.16 5O09-1C nrPDB 34 0.23 4ZLH-A nrPDB 33 0.24 2C2L-A nrPDB 33 0.30 5KYM-A nrPDB 33 0.34 4GN8-A nrPDB 32 0.40 5BT1-A nrPDB 32 0.45 2E54-A nrPDB 32 0.45 4UZY-A nrPDB 32 0.48 6C95-A nrPDB 32 0.50 6C87-A nrPDB 32 0.72 4JA9-A nrPDB 32 0.73 6AHD-N nrPDB 31 1.0 2CG3-A nrPDB 31 1.0 3Q15-A nrPDB 31 1.2 4GNB-A nrPDB 31 1.3 5AEM-A nrPDB 31 1.4 1IHG-A nrPDB 30 1.8 5OMP-A nrPDB 30 2.5 5XJC-J nrPDB 30 3.0 5O6D-A nrPDB 30 3.0 6FRK-r nrPDB 29 4.0 3WCZ-A nrPDB 29 5.7 4HJH-A nrPDB 29 5.8 6GIR-A nrPDB 28 7.6 1ZU2-A nrPDB 28 7.9 4I1A-A nrPDB 28 8.1 4GYO-A nrPDB 28 8.1 5ZYQ-A nrPDB 28 8.1 5BUO-A nrPDB 28 8.3 >4HOQ-A nrPDB Length = 482 Score = 691 bits (1782), Expect = 0.0, Method: Composition-based stats. Identities = 482/482 (100%), Positives = 482/482 (100%) Query: 1 MSEIRKDTLKAILLELECHFTWNLLKEDIDLFEVEDTIGQQLEFLTTKSRLALYNLLAYV 60 MSEIRKDTLKAILLELECHFTWNLLKEDIDLFEVEDTIGQQLEFLTTKSRLALYNLLAYV Sbjct: 1 MSEIRKDTLKAILLELECHFTWNLLKEDIDLFEVEDTIGQQLEFLTTKSRLALYNLLAYV 60 Query: 61 KHLKGQNKDALECLEQAEEIIQQEHSDKEEVRSLVTWGNYAWVYYHMDQLEEAQKYTGKI 120 KHLKGQNKDALECLEQAEEIIQQEHSDKEEVRSLVTWGNYAWVYYHMDQLEEAQKYTGKI Sbjct: 61 KHLKGQNKDALECLEQAEEIIQQEHSDKEEVRSLVTWGNYAWVYYHMDQLEEAQKYTGKI 120 Query: 121 GNVCKKLSSPSNYKLECPETDCEKGWALLKFGGKYYQKAKAAFEKALEVEPDNPEFNIGY 180 GNVCKKLSSPSNYKLECPETDCEKGWALLKFGGKYYQKAKAAFEKALEVEPDNPEFNIGY Sbjct: 121 GNVCKKLSSPSNYKLECPETDCEKGWALLKFGGKYYQKAKAAFEKALEVEPDNPEFNIGY 180 Query: 181 AITVYRLDDSDREGSVKSFSLGPLRKAVTLNPDNSYIKVFLALKLQDVHAEAEGEKYIEE 240 AITVYRLDDSDREGSVKSFSLGPLRKAVTLNPDNSYIKVFLALKLQDVHAEAEGEKYIEE Sbjct: 181 AITVYRLDDSDREGSVKSFSLGPLRKAVTLNPDNSYIKVFLALKLQDVHAEAEGEKYIEE 240 Query: 241 ILDQISSQPYVLRYAAKFYRRKNSWNKALELLKKALEVTPTSSFLHHQMGLCYRAQMIQI 300 ILDQISSQPYVLRYAAKFYRRKNSWNKALELLKKALEVTPTSSFLHHQMGLCYRAQMIQI Sbjct: 241 ILDQISSQPYVLRYAAKFYRRKNSWNKALELLKKALEVTPTSSFLHHQMGLCYRAQMIQI 300 Query: 301 KKATHNRPKGKDKLKVDELISSAIFHFKAAMERDSMFAFAYTDLANMYAEGGQYSNAEDI 360 KKATHNRPKGKDKLKVDELISSAIFHFKAAMERDSMFAFAYTDLANMYAEGGQYSNAEDI Sbjct: 301 KKATHNRPKGKDKLKVDELISSAIFHFKAAMERDSMFAFAYTDLANMYAEGGQYSNAEDI 360 Query: 361 FRKALRLENITDDHKHQIHYHYGRFQEFHRKSENTAIHHYLEALKVKDRSPLRTKLTSAL 420 FRKALRLENITDDHKHQIHYHYGRFQEFHRKSENTAIHHYLEALKVKDRSPLRTKLTSAL Sbjct: 361 FRKALRLENITDDHKHQIHYHYGRFQEFHRKSENTAIHHYLEALKVKDRSPLRTKLTSAL 420 Query: 421 KKLSTKRLCHNALDVQSLSALGFVYKLEGEKRQAAEYYEKAQKIDPENAEFLTALCELRL 480 KKLSTKRLCHNALDVQSLSALGFVYKLEGEKRQAAEYYEKAQKIDPENAEFLTALCELRL Sbjct: 421 KKLSTKRLCHNALDVQSLSALGFVYKLEGEKRQAAEYYEKAQKIDPENAEFLTALCELRL 480 Query: 481 SI 482 SI Sbjct: 481 SI 482 >5UDI-A nrPDB Length = 479 Score = 647 bits (1670), Expect = 0.0, Method: Composition-based stats. Identities = 260/453 (57%), Positives = 340/453 (75%), Gaps = 2/453 (0%) Query: 1 MSEIRKD-TLKAILLELECHFTWNLLKEDIDLFEVEDTIGQQLEFLTTKSRLALYNLLAY 59 MS D +K L +L CHFTW L +D ++ ++E+ + Q+EFL TK + ++NLLAY Sbjct: 2 MSTNGDDHQVKDSLEQLRCHFTWELSIDDDEMPDLENRVLDQIEFLDTKYSVGIHNLLAY 61 Query: 60 VKHLKGQNKDALECLEQAEEIIQQEHSDKEEVRSLVTWGNYAWVYYHMDQLEEAQKYTGK 119 VKHLKGQN++AL+ L++AE ++Q+EH ++ VRSLVTWGN+AW+YYHM +L EAQ Y K Sbjct: 62 VKHLKGQNEEALKSLKEAENLMQEEHDNQANVRSLVTWGNFAWMYYHMGRLAEAQTYLDK 121 Query: 120 IGNVCKKLSSPSNYKLECPETDCEKGWALLKFGGKYYQKAKAAFEKALEVEPDNPEFNIG 179 + N+CKKLS+P Y++ECPE DCE+GWALLK GGK Y++AKA FEK LEV+P+NPE + G Sbjct: 122 VENICKKLSNPFRYRMECPEIDCEEGWALLKCGGKNYERAKACFEKVLEVDPENPESSAG 181 Query: 180 YAITVYRLDDSD-REGSVKSFSLGPLRKAVTLNPDNSYIKVFLALKLQDVHAEAEGEKYI 238 YAI+ YRLD + K FSL PLR+AV LNPDN YIKV LALKLQD EAEGEKYI Sbjct: 182 YAISAYRLDGFKLATKNHKPFSLLPLRQAVRLNPDNGYIKVLLALKLQDEGQEAEGEKYI 241 Query: 239 EEILDQISSQPYVLRYAAKFYRRKNSWNKALELLKKALEVTPTSSFLHHQMGLCYRAQMI 298 EE L +SSQ YV RYAAKFYRRK S +KALELLKKAL+ TPTS LHHQ+GLCY+AQMI Sbjct: 242 EEALANMSSQTYVFRYAAKFYRRKGSVDKALELLKKALQETPTSVLLHHQIGLCYKAQMI 301 Query: 299 QIKKATHNRPKGKDKLKVDELISSAIFHFKAAMERDSMFAFAYTDLANMYAEGGQYSNAE 358 QIK+AT +P+G+++ K+D++I SAIFHF++A+E+ F A+ DLA MY E G + AE Sbjct: 302 QIKEATKGQPRGQNREKLDKMIRSAIFHFESAVEKKPTFEVAHLDLARMYIEAGNHRKAE 361 Query: 359 DIFRKALRLENITDDHKHQIHYHYGRFQEFHRKSENTAIHHYLEALKVKDRSPLRTKLTS 418 + F+K L ++ + ++ IH+HYGRFQEF +KS+ AI HYL+A+K++ S R K + Sbjct: 362 ENFQKLLCMKPVVEETMQDIHFHYGRFQEFQKKSDVNAIIHYLKAIKIEQASLTRDKSIN 421 Query: 419 ALKKLSTKRLCHNALDVQSLSALGFVYKLEGEK 451 +LKKL ++L ALD++SLS LGFVYKLEG Sbjct: 422 SLKKLVLRKLRRKALDLESLSLLGFVYKLEGNM 454 >4G1T-A nrPDB Length = 472 Score = 593 bits (1528), Expect = e-170, Method: Composition-based stats. Identities = 215/465 (46%), Positives = 297/465 (63%), Gaps = 13/465 (2%) Query: 1 MSEIRKDTLKAILLELECHFTWNLLKEDIDLFEVEDTIGQQLEFLTTKSRLALYNLLAYV 60 MSE K++L++ L +L+CHFTWNL++ + L + ED + + EF + + + NLLAY+ Sbjct: 1 MSENNKNSLESSLRQLKCHFTWNLMEGENSLDDFEDKVFYRTEFQNREFKATMCNLLAYL 60 Query: 61 KHLKGQNKDALECLEQAEEIIQQEHSDKEEVRSLVTWGNYAWVYYHMDQLEEAQKYTGKI 120 KHLKGQN+ ALECL +AEE+IQQEH+D+ E+RSLVTWGNYAWVYYHM +L + Q Y K+ Sbjct: 61 KHLKGQNEAALECLRKAEELIQQEHADQAEIRSLVTWGNYAWVYYHMGRLSDVQIYVDKV 120 Query: 121 GNVCKKLSSPSNYKLECPETDCEKGWALLKFGGKYYQKAKAAFEKALEVEPDNPEFNIGY 180 +VC+K SSP Y++E PE DCE+GW LK GG ++AK FEKALE +P NPEF G Sbjct: 121 KHVCEKFSSP--YRIESPELDCEEGWTRLKCGGNQNERAKVCFEKALEKKPKNPEFTSGL 178 Query: 181 AITVYRLDDSDREGSVKSFSLGPLRKAVTLNPDNSYIKVFLALKLQDVH----AEAEGEK 236 AI YRLD+ + ++ PLR+A+ LNPDN Y+KV LALKL + E EGEK Sbjct: 179 AIASYRLDNWPPSQN----AIDPLRQAIRLNPDNQYLKVLLALKLHKMREEGEEEGEGEK 234 Query: 237 YIEEILDQISSQPYVLRYAAKFYRRKNSWNKALELLKKALEVTPTSSFLHHQMGLCYRAQ 296 +EE L++ VLR AAKFYRRK+ +KA+ELLKKALE P +++LH Q+G CYRA+ Sbjct: 235 LVEEALEKAPGVTDVLRSAAKFYRRKDEPDKAIELLKKALEYIPNNAYLHCQIGCCYRAK 294 Query: 297 MIQIKKATHNRPKGKDKLKVDELISSAIFHFKAAMERDSMFAFAYTDLANMYAEGGQYSN 356 + Q+ N GK KL ELI A+ H K A E + + LA+++A QY Sbjct: 295 VFQVMNLRENGMYGKRKLL--ELIGHAVAHLKKADEANDNLFRVCSILASLHALADQYEE 352 Query: 357 AEDIFRKALRLENITDDHKHQIHYHYGRFQEFHRKSENTAIHHYLEALKVKDRSPLRTKL 416 AE F+K E +T K +H YG FQ + K E+ AIHH++E +K+ +S + K+ Sbjct: 353 AEYYFQKEFSKE-LTPVAKQLLHLRYGNFQLYQMKCEDKAIHHFIEGVKINQKSREKEKM 411 Query: 417 TSALKKLSTKRLCHNALDVQSLSALGFVYKLEGEKRQAAEYYEKA 461 L+K++ RL N D ++L L F+ +L + +QA E E+ Sbjct: 412 KDKLQKIAKMRLSKNGADSEALHVLAFLQELNEKMQQADEDSERG 456 >4HOU-A nrPDB Length = 273 Score = 427 bits (1098), Expect = e-120, Method: Composition-based stats. Identities = 167/270 (61%), Positives = 210/270 (77%), Gaps = 1/270 (0%) Query: 9 LKAILLELECHFTWNLLKEDIDLFEVEDTIGQQLEFLTTKSRLALYNLLAYVKHLKGQNK 68 +K L +L CHFTW L +D ++ ++E+ + Q+EFL TK + ++NLLAYVKHLKGQN+ Sbjct: 4 VKDSLEQLRCHFTWELSIDDDEMPDLENRVLDQIEFLDTKYSVGIHNLLAYVKHLKGQNE 63 Query: 69 DALECLEQAEEIIQQEHSDKEEVRSLVTWGNYAWVYYHMDQLEEAQKYTGKIGNVCKKLS 128 +AL+ L++AE ++Q+EH ++ VRSLVTWGN+AW+YYHM +L EAQ Y K+ N+CKKLS Sbjct: 64 EALKSLKEAENLMQEEHDNQANVRSLVTWGNFAWMYYHMGRLAEAQTYLDKVENICKKLS 123 Query: 129 SPSNYKLECPETDCEKGWALLKFGGKYYQKAKAAFEKALEVEPDNPEFNIGYAITVYRLD 188 +P Y++ECPE DCE+GWALLK GGK Y++AKA FEK LEV+P+NPE + GYAI+ YRLD Sbjct: 124 NPFRYRMECPEIDCEEGWALLKCGGKNYERAKACFEKVLEVDPENPESSAGYAISAYRLD 183 Query: 189 DSD-REGSVKSFSLGPLRKAVTLNPDNSYIKVFLALKLQDVHAEAEGEKYIEEILDQISS 247 + K FSL PLR+AV LNPDN YIKV LALKLQD EAEGEKYIEE L +SS Sbjct: 184 GFKLATKNHKPFSLLPLRQAVRLNPDNGYIKVLLALKLQDEGQEAEGEKYIEEALANMSS 243 Query: 248 QPYVLRYAAKFYRRKNSWNKALELLKKALE 277 Q YV RYAAKFYRRK S +KALELLKKAL+ Sbjct: 244 QTYVFRYAAKFYRRKGSVDKALELLKKALQ 273 >1W3B-A nrPDB Length = 388 Score = 195 bits (495), Expect = 4e-50, Method: Composition-based stats. Identities = 46/198 (23%), Positives = 81/198 (40%), Gaps = 28/198 (14%) Query: 153 GKYYQKAKAAFEKALEVEPDNPEFNIGYAITVYRLDDSDREGSVKSFSLGPLRKAVTLNP 212 + + +A AA+ +AL + P++ + A Y E + ++ R+A+ L P Sbjct: 216 ARIFDRAVAAYLRALSLSPNHAVVHGNLACVYY-------EQGLIDLAIDTYRRAIELQP 268 Query: 213 DNSYIKVFLALKLQDVHAEAEGEKYIEEILDQISSQPYVLRYAAKFYRRKNSWNKALELL 272 LA L++ + AE E L + L A R + + +A+ L Sbjct: 269 HFPDAYCNLANALKEKGSVAEAEDCYNTALRLCPTHADSLNNLANIKREQGNIEEAVRLY 328 Query: 273 KKALEVTPTSSFLHHQMGLCYRAQMIQIKKATHNRPKGKDKLKVDELISSAIFHFKAAME 332 +KALEV P + H + A ++Q +GK + A+ H+K A+ Sbjct: 329 RKALEVFPEFAAAHSNL-----ASVLQ--------QQGK--------LQEALMHYKEAIR 367 Query: 333 RDSMFAFAYTDLANMYAE 350 FA AY+++ N E Sbjct: 368 ISPTFADAYSNMGNTLKE 385 Score = 167 bits (423), Expect = 8e-42, Method: Composition-based stats. Identities = 48/165 (29%), Positives = 78/165 (47%), Gaps = 19/165 (11%) Query: 325 FHFKA-AMERDSMFAFAYTDLANMYAEGGQYSNAEDIFRKALRLENITDDHKHQIHYHYG 383 HF A++++ + A AY++L N+Y E GQ A + +R ALRL+ D + Sbjct: 53 AHFSTLAIKQNPLLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALV 112 Query: 384 RFQEFHRKSENTAIHHYLEALKVK-DRSPLRTKLTS---ALKKLSTKRLCH-NALDVQ-- 436 + A+ Y+ AL+ D +R+ L + AL +L + C+ A++ Q Sbjct: 113 AAGDME-----GAVQAYVSALQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQPN 167 Query: 437 ---SLSALGFVYKLEGEKRQAAEYYEKAQKIDPENAEFLTALCEL 478 + S LG V+ +GE A ++EKA +DP FL A L Sbjct: 168 FAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDP---NFLDAYINL 209 Score = 126 bits (317), Expect = 2e-29, Method: Composition-based stats. Identities = 48/270 (17%), Positives = 96/270 (35%), Gaps = 24/270 (8%) Query: 131 SNYKLECPETDCEKGWALLKFGGKYYQKAKAAFEKALEVEPDNPEFNIGYAITVYRLDDS 190 N L C +D LLK G+ ++AKA + KA+E +P+ Sbjct: 130 YNPDLYCVRSDLGN---LLKALGRL-EEAKACYLKAIETQPNFAVAWSNLGCVF------ 179 Query: 191 DREGSVKSFSLGPLRKAVTLNPDNSYIKVFLALKLQDVHAEAEGEKYIEEILDQISSQPY 250 ++ KAVTL+P+ + L L++ L + Sbjct: 180 -NAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAV 238 Query: 251 VLRYAAKFYRRKNSWNKALELLKKALEVTPTSSFLHHQMGL-------------CYRAQM 297 V A Y + + A++ ++A+E+ P + + CY + Sbjct: 239 VHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGSVAEAEDCYNTAL 298 Query: 298 IQIKKATHNRPKGKDKLKVDELISSAIFHFKAAMERDSMFAFAYTDLANMYAEGGQYSNA 357 + + + I A+ ++ A+E FA A+++LA++ + G+ A Sbjct: 299 RLCPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEA 358 Query: 358 EDIFRKALRLENITDDHKHQIHYHYGRFQE 387 +++A+R+ D + Q+ Sbjct: 359 LMHYKEAIRISPTFADAYSNMGNTLKEMQD 388 Score = 103 bits (257), Expect = 2e-22, Method: Composition-based stats. Identities = 64/326 (19%), Positives = 108/326 (33%), Gaps = 39/326 (11%) Query: 180 YAITVYRLDDSDREGSVKSFSLGPLRKAVTLNPDNSYIKVFLALKLQDVHAEAEGEKYIE 239 A L + +E ++ R A+ L PD + LA L + Sbjct: 66 LAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDMEGAVQAYV 125 Query: 240 EILDQISSQPYVLRYAAKFYRRKNSWNKALELLKKALEVTPTSSFLHHQMGLCYRAQMIQ 299 L V + +A KA+E P + +G + AQ + Sbjct: 126 SALQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQG-E 184 Query: 300 IKKATHNRPKG--------------KDKLKVDELISSAIFHFKAAMERDSMFAFAYTDLA 345 I A H+ K + LK + A+ + A+ A + +LA Sbjct: 185 IWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLA 244 Query: 346 NMYAEGGQYSNAEDIFRKALRLENITDDHKHQIHYHYGRFQEFHRKSENTAIHHYLEALK 405 +Y E G A D +R+A+ L+ D + + S A Y AL+ Sbjct: 245 CVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALK-----EKGSVAEAEDCYNTALR 299 Query: 406 VKDRSPLRTKLTSALKKL--------STKRLCHNALDV-----QSLSALGFVYKLEGEKR 452 P + L + RL AL+V + S L V + +G+ + Sbjct: 300 ---LCPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQ 356 Query: 453 QAAEYYEKAQKIDPENAEFLTALCEL 478 +A +Y++A +I P F A + Sbjct: 357 EALMHYKEAIRISPT---FADAYSNM 379 Score = 85.6 bits (210), Expect = 4e-17, Method: Composition-based stats. Identities = 46/272 (16%), Positives = 80/272 (29%), Gaps = 53/272 (19%) Query: 207 AVTLNPDNSYIKVFLALKLQDVHAEAEGEKYIEEILDQISSQPYVLRYAAKFYRRKNSWN 266 A+ NP + L ++ E ++ L A Sbjct: 59 AIKQNPLLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDME 118 Query: 267 KALELLKKALEVTPTSSFLHHQMGLCYRAQMIQIKKATHNRPKGKDKLKVDELISSAIFH 326 A++ AL+ P + +G + LK + A Sbjct: 119 GAVQAYVSALQYNPDLYCVRSDLG---------------------NLLKALGRLEEAKAC 157 Query: 327 FKAAMERDSMFAFAYTDLANMYAEGGQYSNAEDIFRKALRLENITDDHKHQIHYHYGRFQ 386 + A+E FA A+++L ++ G+ A F KA+ L+ D + + Sbjct: 158 YLKAIETQPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEAR 217 Query: 387 EFHRKSENTAIHHYLEALKVKDRSPLRTKLTSALKKLSTKRLCHNALDVQSLSALGFVYK 446 F + A+ YL AL + + L VY Sbjct: 218 IF-----DRAVAAYLRALSLSPNHAVVH------------------------GNLACVYY 248 Query: 447 LEGEKRQAAEYYEKAQKIDPENAEFLTALCEL 478 +G A + Y +A ++ P F A C L Sbjct: 249 EQGLIDLAIDTYRRAIELQP---HFPDAYCNL 277 >5A01-A nrPDB Length = 710 Score = 105 bits (262), Expect = 4e-23, Method: Composition-based stats. Identities = 34/148 (22%), Positives = 63/148 (42%), Gaps = 13/148 (8%) Query: 245 ISSQPYVLRYAAKFYRRKNSWNKALELLKKALEVTPTSSFLHHQMGLCYRAQ------MI 298 S+ L A R + +A L KALEV P + H + + Q ++ Sbjct: 3 CSNHADSLNNLANIKREQGYIEEATRLYLKALEVFPDFAAAHSNLASVLQQQGKLKEALM 62 Query: 299 QIKKATHNRP-------KGKDKLKVDELISSAIFHFKAAMERDSMFAFAYTDLANMYAEG 351 K+A +P + LK + +S A+ + A++ + FA A+++LA+++ + Sbjct: 63 HYKEAIRIQPTFADAYSNMGNTLKELQDVSGALQCYTRAIQINPAFADAHSNLASIHKDS 122 Query: 352 GQYSNAEDIFRKALRLENITDDHKHQIH 379 G A +R AL+L+ D + Sbjct: 123 GNIPEAIQSYRTALKLKPDFPDAYCNLA 150 Score = 82.5 bits (202), Expect = 3e-16, Method: Composition-based stats. Identities = 23/152 (15%), Positives = 56/152 (36%), Gaps = 7/152 (4%) Query: 141 DCEKGWALLKFGGKYYQKAKAAFEKALEVEPDNPEFNIGYAITVYRLDDSDREGSVKSFS 200 D A +K Y ++A + KALEV PD + A + ++ + Sbjct: 8 DSLNNLANIKREQGYIEEATRLYLKALEVFPDFAAAHSNLASVL-------QQQGKLKEA 60 Query: 201 LGPLRKAVTLNPDNSYIKVFLALKLQDVHAEAEGEKYIEEILDQISSQPYVLRYAAKFYR 260 L ++A+ + P + + L+++ + + + + A ++ Sbjct: 61 LMHYKEAIRIQPTFADAYSNMGNTLKELQDVSGALQCYTRAIQINPAFADAHSNLASIHK 120 Query: 261 RKNSWNKALELLKKALEVTPTSSFLHHQMGLC 292 + +A++ + AL++ P + + C Sbjct: 121 DSGNIPEAIQSYRTALKLKPDFPDAYCNLAHC 152 Score = 74.4 bits (181), Expect = 1e-13, Method: Composition-based stats. Identities = 43/251 (17%), Positives = 86/251 (34%), Gaps = 24/251 (9%) Query: 178 IGYAITVYRLDDSDREGSVKSFSLGPLRKAVTLNPDNSYIKVFLALKLQDVHAEAEGEKY 237 +A ++ L + RE + KA+ + PD + LA LQ E + Sbjct: 4 SNHADSLNNLANIKREQGYIEEATRLYLKALEVFPDFAAAHSNLASVLQQQGKLKEALMH 63 Query: 238 IEEILDQISSQPYVLRYAAKFYRRKNSWNKALELLKKALEVTPTSSFLHHQMGLCYRAQM 297 +E + + + + AL+ +A+++ P + H + ++ Sbjct: 64 YKEAIRIQPTFADAYSNMGNTLKELQDVSGALQCYTRAIQINPAFADAHSNLASIHKDS- 122 Query: 298 IQIKKATHNRPKGKDKLKVDELISSAIFHFKAAMERDSMFAFAYTDLANMYAEGGQYSNA 357 I AI ++ A++ F AY +LA+ +++ Sbjct: 123 --------------------GNIPEAIQSYRTALKLKPDFPDAYCNLAHCLQIVCDWTDY 162 Query: 358 EDIFRKALRL--ENITDDHKHQIHYHYGRFQEFHRKSENTAIHHYLEALKVKDRSPLRTK 415 + +K + + E + + +H H+ AI L ++ L K Sbjct: 163 DIRMKKLVSIVTEQLEKNRLPSVHPHHSMLYPLTHDCR-KAIAARHANLCLEKVHVLHKK 221 Query: 416 LTSALKKLSTK 426 + LKKL TK Sbjct: 222 PYNFLKKLPTK 232 Score = 51.3 bits (121), Expect = 1e-06, Method: Composition-based stats. Identities = 26/172 (15%), Positives = 57/172 (33%), Gaps = 28/172 (16%) Query: 55 NLLAYVKHLKGQNKDALECLEQAEEIIQQEHSDKEEVRSLVTWGNYAWVYYHMDQLEEAQ 114 N LA +K +G ++A +A E+ + + S++ +L+EA Sbjct: 11 NNLANIKREQGYIEEATRLYLKALEVFPDFAAAHSNLASVLQ---------QQGKLKEAL 61 Query: 115 KYTGKIGNVCKKLSSPSNYKLECPETDCEKGWALLKFGGKYYQKAKAAFEKALEVEPDNP 174 + + + + ++ L+ A + +A+++ P Sbjct: 62 MHYKEAIRIQPTFADAY--------SNMGNTLKELQ----DVSGALQCYTRAIQINPAFA 109 Query: 175 EFNIGYAITVYRLDDSDREGSVKSFSLGPLRKAVTLNPDNSYIKVFLALKLQ 226 + + A ++ ++ R A+ L PD LA LQ Sbjct: 110 DAHSNLASIH-------KDSGNIPEAIQSYRTALKLKPDFPDAYCNLAHCLQ 154 Score = 31.3 bits (69), Expect = 0.89, Method: Composition-based stats. Identities = 16/60 (26%), Positives = 28/60 (46%), Gaps = 8/60 (13%) Query: 424 STKRLCHNALDV-----QSLSALGFVYKLEGEKRQAAEYYEKAQKIDPENAEFLTALCEL 478 RL AL+V + S L V + +G+ ++A +Y++A +I P F A + Sbjct: 25 EATRLYLKALEVFPDFAAAHSNLASVLQQQGKLKEALMHYKEAIRIQPT---FADAYSNM 81 >5LVV-A nrPDB Length = 749 Score = 81.3 bits (199), Expect = 8e-16, Method: Composition-based stats. Identities = 34/235 (14%), Positives = 78/235 (33%), Gaps = 22/235 (9%) Query: 141 DCEKGWALLKFGGKYYQKAKAAFEKALEVEPDNPEFNIGYAITVYRLDDSDREGSVKSFS 200 D A +K ++A + KALEV P+ + A + ++ + Sbjct: 31 DSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVL-------QQQGKLQEA 83 Query: 201 LGPLRKAVTLNPDNSYIKVFLALKLQDVHAEAEGEKYIEEILDQISSQPYVLRYAAKFYR 260 L ++A+ ++P + + L+++ + + + A ++ Sbjct: 84 LMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHK 143 Query: 261 RKNSWNKALELLKKALEVTPTSSFLHHQMGLCYRAQMIQIKKATHNRPKGKDKLKVDELI 320 + +A+ + AL++ P + + C +QI D DE + Sbjct: 144 DSGNIPEAIASYRTALKLKPDFPDAYCNLAHC-----LQIVC---------DWTDYDERM 189 Query: 321 SSAIFHFKAAMERDSMFAFAYTDLANMYAEGGQYSNAEDIFRKALRLENITDDHK 375 + +E++ + + +Y + A L L+ I HK Sbjct: 190 KKLVSIVADQLEKN-RLPSVHPHHSMLYPLSHGFRKAIAERHGNLCLDKINVLHK 243 Score = 77.9 bits (190), Expect = 9e-15, Method: Composition-based stats. Identities = 29/190 (15%), Positives = 67/190 (35%), Gaps = 21/190 (11%) Query: 178 IGYAITVYRLDDSDREGSVKSFSLGPLRKAVTLNPDNSYIKVFLALKLQDVHAEAEGEKY 237 +A ++ L + RE ++ RKA+ + P+ + LA LQ E + Sbjct: 27 GTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMH 86 Query: 238 IEEILDQISSQPYVLRYAAKFYRRKNSWNKALELLKKALEVTPTSSFLHHQMGLCYRAQM 297 +E + + + AL+ +A+++ P + H + ++ Sbjct: 87 YKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDS- 145 Query: 298 IQIKKATHNRPKGKDKLKVDELISSAIFHFKAAMERDSMFAFAYTDLANMYAEGGQYSNA 357 I AI ++ A++ F AY +LA+ +++ Sbjct: 146 --------------------GNIPEAIASYRTALKLKPDFPDAYCNLAHCLQIVCDWTDY 185 Query: 358 EDIFRKALRL 367 ++ +K + + Sbjct: 186 DERMKKLVSI 195 Score = 71.7 bits (174), Expect = 7e-13, Method: Composition-based stats. Identities = 31/159 (19%), Positives = 59/159 (37%), Gaps = 32/159 (20%) Query: 320 ISSAIFHFKAAMERDSMFAFAYTDLANMYAEGGQYSNAEDIFRKALRLENITDDHKHQIH 379 I A+ ++ A+E FA A+++LA++ + G+ A +++A+R+ D + Sbjct: 46 IEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMG 105 Query: 380 YHYGRFQEFHRKSENTAIHHYLEALKVKDRSPLRTKLTSALKKLSTKRLCHNALDVQSLS 439 Q+ A+ Y A+++ + S Sbjct: 106 NTLKEMQDVQ-----GALQCYTRAIQINPAF------------------------ADAHS 136 Query: 440 ALGFVYKLEGEKRQAAEYYEKAQKIDPENAEFLTALCEL 478 L ++K G +A Y A K+ P +F A C L Sbjct: 137 NLASIHKDSGNIPEAIASYRTALKLKP---DFPDAYCNL 172 Score = 57.8 bits (138), Expect = 9e-09, Method: Composition-based stats. Identities = 26/172 (15%), Positives = 60/172 (34%), Gaps = 28/172 (16%) Query: 55 NLLAYVKHLKGQNKDALECLEQAEEIIQQEHSDKEEVRSLVTWGNYAWVYYHMDQLEEAQ 114 N LA +K +G ++A+ +A E+ + + + S++ +L+EA Sbjct: 34 NNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQ---------QQGKLQEAL 84 Query: 115 KYTGKIGNVCKKLSSPSNYKLECPETDCEKGWALLKFGGKYYQKAKAAFEKALEVEPDNP 174 + + + + ++ ++ Q A + +A+++ P Sbjct: 85 MHYKEAIRISPTFADAY--------SNMGNTLKEMQ----DVQGALQCYTRAIQINPAFA 132 Query: 175 EFNIGYAITVYRLDDSDREGSVKSFSLGPLRKAVTLNPDNSYIKVFLALKLQ 226 + + A ++ ++ R A+ L PD LA LQ Sbjct: 133 DAHSNLASIH-------KDSGNIPEAIASYRTALKLKPDFPDAYCNLAHCLQ 177 >5G04-F nrPDB Length = 824 Score = 60.9 bits (146), Expect = 1e-09, Method: Composition-based stats. Identities = 45/227 (19%), Positives = 90/227 (39%), Gaps = 38/227 (16%) Query: 255 AAKFYRRKNSWNKALELLKKALEVTPTSSFLHHQMGLCYRAQMIQIKKATHNRPKGKDKL 314 A + + + A++ ++A++V P ++ + +G + Sbjct: 573 AGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLG---------------------HEF 611 Query: 315 KVDELISSAIFHFKAAMERDSMFAFAYTDLANMYAEGGQYSNAEDIFRKALRLENITDDH 374 + E + A+ F+ A+ + A+ L +Y + ++S AE F+KAL + + Sbjct: 612 VLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSV- 670 Query: 375 KHQIHYHYGRFQEFHRKSENTAIHHYLEALKVKDRSPL-----------RTKLTSALKKL 423 + H G Q +KSE A+ +A+ + ++PL K SAL++L Sbjct: 671 ---LLCHIGVVQHALKKSE-KALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQEL 726 Query: 424 STKRLCHNALDVQSLSALGFVYKLEGEKRQAAEYYEKAQKIDPENAE 470 + + +G VYK G+ A + A +DP+ A Sbjct: 727 EELKQIVPK-ESLVYFLIGKVYKKLGQTHLALMNFSWAMDLDPKGAN 772 Score = 58.6 bits (140), Expect = 6e-09, Method: Composition-based stats. Identities = 46/287 (16%), Positives = 96/287 (33%), Gaps = 31/287 (10%) Query: 99 NYAWVYYHMDQLE-EAQKYTGKIGNVCKKLSSPSNYKLECPETDCEKGWALLKFGGKYYQ 157 N WV + + E +Y + + ++ NY++E E W L K Sbjct: 497 NTGWVLCQIGRAYFELSEYM-QAERIFSEVRRIENYRVEGMEIYSTTLWHLQK------D 549 Query: 158 KAKAAFEKAL-EVEPDNPEFNIGYAITVYRLDDSDREGSVKSFSLGPLRKAVTLNPDNSY 216 A + K L +++ ++PE + ++ ++A+ ++P+ +Y Sbjct: 550 VALSVLSKDLTDMDKNSPE-------AWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAY 602 Query: 217 IKVFLALKLQDVHAEAEGEKYIEEILDQISSQPYVLRYAAKFYRRKNSWNKALELLKKAL 276 L + + + Y ++ ++ A +KAL Sbjct: 603 AYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKAL 662 Query: 277 EVTPTSSFLHHQMGLCY--------------RAQMIQIKKATHNRPKGKDKLKVDELISS 322 ++ P SS L +G+ +A +I K + L +E S Sbjct: 663 DINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRA-SVLFANEKYKS 721 Query: 323 AIFHFKAAMERDSMFAFAYTDLANMYAEGGQYSNAEDIFRKALRLEN 369 A+ + + + Y + +Y + GQ A F A+ L+ Sbjct: 722 ALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDLDP 768 Score = 44.4 bits (103), Expect = 1e-04, Method: Composition-based stats. Identities = 38/205 (18%), Positives = 80/205 (39%), Gaps = 14/205 (6%) Query: 81 IQQEHSDKEEV--RSLVTWGNYAWVYYHMDQLEEAQKYTGKIGNVCKKLSSPSNYKLECP 138 +Q+EH + R++ NYA+ Y + + K C + + N + Sbjct: 579 LQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKAL-ACFRNAIRVNPRHY-- 635 Query: 139 ETDCEKGWALLKFGGKYYQKAKAAFEKALEVEPDNPEFNIGYAITVYRLDDSDREGSVKS 198 + G ++ + + + A+ F+KAL++ P + + + L S++ Sbjct: 636 --NAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEK------ 687 Query: 199 FSLGPLRKAVTLNPDNSYIKVFLALKLQDVHAEAEGEKYIEEILDQISSQPYVLRYAAKF 258 +L L KA+ ++P N K A L + +EE+ + + V K Sbjct: 688 -ALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIGKV 746 Query: 259 YRRKNSWNKALELLKKALEVTPTSS 283 Y++ + AL A+++ P + Sbjct: 747 YKKLGQTHLALMNFSWAMDLDPKGA 771 Score = 40.9 bits (94), Expect = 0.001, Method: Composition-based stats. Identities = 29/222 (13%), Positives = 86/222 (38%), Gaps = 42/222 (18%) Query: 264 SWNKALELLKKALEVTPTSSFLHHQMGLCY--RAQMIQIKKATHNRPKGKD-KLKVDELI 320 + +A+ +L + ++ Q+G Y ++ +Q ++ + ++ +++ E+ Sbjct: 480 NCKEAINILSHLPSHHYNTGWVLCQIGRAYFELSEYMQAERIFSEVRRIENYRVEGMEIY 539 Query: 321 SSAIFHFKAAM----------ERDSMFAFAYTDLANMYAEGGQYSNAEDIFRKALRLENI 370 S+ ++H + + + D A+ N ++ ++ A F++A++++ Sbjct: 540 STTLWHLQKDVALSVLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPN 599 Query: 371 TDDHKHQIHYHYGRFQEFHRKSENTAIHHYLEALKVKDRSPLRTKLTSALKKLSTKRLCH 430 + + + +E + A+ + A++V R Sbjct: 600 YAYAYTLLGHEFVLTEEL-----DKALACFRNAIRVNPRH-------------------- 634 Query: 431 NALDVQSLSALGFVYKLEGEKRQAAEYYEKAQKIDPENAEFL 472 + LG +Y + + A +++KA I+P+++ L Sbjct: 635 ----YNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLL 672 >6B85-J nrPDB Length = 223 Score = 57.5 bits (137), Expect = 1e-08, Method: Composition-based stats. Identities = 25/130 (19%), Positives = 53/130 (40%), Gaps = 7/130 (5%) Query: 159 AKAAFEKALEVEPDNPEFNIGYAITVYRLDDSDREGSVKSFSLGPLRKAVTLNPDNSYIK 218 A A++KA+E++P++ A+ L + + +KA+ L P+++ Sbjct: 100 AAEAYKKAIELDPND-------ALAWLLLGSVLEKLKRLDEAAEAYKKAIELKPNDASAW 152 Query: 219 VFLALKLQDVHAEAEGEKYIEEILDQISSQPYVLRYAAKFYRRKNSWNKALELLKKALEV 278 L L+ + E + ++ ++ + K + ++A E KKA+E+ Sbjct: 153 KELGKVLEKLGRLDEAAEAYKKAIELDPEDAEAWKELGKVLEKLGRLDEAAEAYKKAIEL 212 Query: 279 TPTSSFLHHQ 288 P HH Sbjct: 213 DPNDLEHHHH 222 Score = 51.3 bits (121), Expect = 1e-06, Method: Composition-based stats. Identities = 19/110 (17%), Positives = 46/110 (41%) Query: 181 AITVYRLDDSDREGSVKSFSLGPLRKAVTLNPDNSYIKVFLALKLQDVHAEAEGEKYIEE 240 A+ L + S + +KA+ L+P+++ + L L+ + E + ++ Sbjct: 81 ALAYVMLGLLLSLLNRLSLAAEAYKKAIELDPNDALAWLLLGSVLEKLKRLDEAAEAYKK 140 Query: 241 ILDQISSQPYVLRYAAKFYRRKNSWNKALELLKKALEVTPTSSFLHHQMG 290 ++ + + K + ++A E KKA+E+ P + ++G Sbjct: 141 AIELKPNDASAWKELGKVLEKLGRLDEAAEAYKKAIELDPEDAEAWKELG 190 Score = 46.3 bits (108), Expect = 3e-05, Method: Composition-based stats. Identities = 28/160 (17%), Positives = 60/160 (37%), Gaps = 21/160 (13%) Query: 217 IKVFLALKLQDVHAEAEGEKYIEEILDQISSQPYVLRYAAKFYRRKNSWNKALELLKKAL 276 V L L L ++ + + ++ ++ + + ++A E KKA+ Sbjct: 83 AYVMLGLLLSLLNRLSLAAEAYKKAIELDPNDALAWLLLGSVLEKLKRLDEAAEAYKKAI 142 Query: 277 EVTPTSSFLHHQMGLCYRAQMIQIKKATHNRPKGKDKLKVDELISSAIFHFKAAMERDSM 336 E+ P + ++G L+ + A +K A+E D Sbjct: 143 ELKPNDASAWKELG---------------------KVLEKLGRLDEAAEAYKKAIELDPE 181 Query: 337 FAFAYTDLANMYAEGGQYSNAEDIFRKALRLENITDDHKH 376 A A+ +L + + G+ A + ++KA+ L+ +H H Sbjct: 182 DAEAWKELGKVLEKLGRLDEAAEAYKKAIELDPNDLEHHH 221 Score = 44.7 bits (104), Expect = 8e-05, Method: Composition-based stats. Identities = 28/144 (19%), Positives = 56/144 (38%), Gaps = 29/144 (20%) Query: 327 FKAAMERDSMFAFAYTDLANMYAEGGQYSNAEDIFRKALRLENITDDHKHQIHYHYGRFQ 386 +K A+E D A A+ L ++ + + A + ++KA+ L+ ++ + Sbjct: 104 YKKAIELDPNDALAWLLLGSVLEKLKRLDEAAEAYKKAIELKPNDASAWKELGKVLEKLG 163 Query: 387 EFHRKSENTAIHHYLEALKVKDRSPLRTKLTSALKKLSTKRLCHNALDVQSLSALGFVYK 446 + A Y +A+++ D ++ LG V + Sbjct: 164 RL-----DEAAEAYKKAIELDPE------------------------DAEAWKELGKVLE 194 Query: 447 LEGEKRQAAEYYEKAQKIDPENAE 470 G +AAE Y+KA ++DP + E Sbjct: 195 KLGRLDEAAEAYKKAIELDPNDLE 218 Score = 40.1 bits (92), Expect = 0.002, Method: Composition-based stats. Identities = 39/209 (18%), Positives = 78/209 (37%), Gaps = 37/209 (17%) Query: 208 VTLNPDNSYIKVFLALKLQDVHA---------EAEGEKYIEEILDQISSQPYVLRYAAKF 258 +T NPD S I L+++L + + E+ E I +S+ YV+ Sbjct: 33 ITTNPDTSQIATLLSMQLLLIALMLVVIALLLSRQTEQVAESIRRDVSALAYVMLGLLL- 91 Query: 259 YRRKNSWNKALELLKKALEVTPTSSFLHHQMGLCYRAQMIQIKKATHNRPKGKDKLKVDE 318 N + A E KKA+E+ P + +G L+ + Sbjct: 92 -SLLNRLSLAAEAYKKAIELDPNDALAWLLLG---------------------SVLEKLK 129 Query: 319 LISSAIFHFKAAMERDSMFAFAYTDLANMYAEGGQYSNAEDIFRKALRLENITDDHKHQI 378 + A +K A+E A A+ +L + + G+ A + ++KA+ L+ + ++ Sbjct: 130 RLDEAAEAYKKAIELKPNDASAWKELGKVLEKLGRLDEAAEAYKKAIELDPEDAEAWKEL 189 Query: 379 HYHYGRFQEFHRKSENTAIHHYLEALKVK 407 + + A Y +A+++ Sbjct: 190 GKVLEKLGRL-----DEAAEAYKKAIELD 213 Score = 35.1 bits (79), Expect = 0.062, Method: Composition-based stats. Identities = 23/85 (27%), Positives = 37/85 (43%), Gaps = 10/85 (11%) Query: 396 AIHHYLEALKVKD----RSPLRTKLTSALKKLSTKRLCHNAL------DVQSLSALGFVY 445 A Y +A+++ L + LK+L + D + LG V Sbjct: 100 AAEAYKKAIELDPNDALAWLLLGSVLEKLKRLDEAAEAYKKAIELKPNDASAWKELGKVL 159 Query: 446 KLEGEKRQAAEYYEKAQKIDPENAE 470 + G +AAE Y+KA ++DPE+AE Sbjct: 160 EKLGRLDEAAEAYKKAIELDPEDAE 184 >5G05-C nrPDB Length = 597 Score = 51.3 bits (121), Expect = 8e-07, Method: Composition-based stats. Identities = 43/238 (18%), Positives = 79/238 (33%), Gaps = 43/238 (18%) Query: 254 YAAKFYRRKNSWNKALELLKKALEV-TPTSSFLHHQMGLCYR------AQMIQIKKATHN 306 + A Y +AL+ + ++V SS++ Q+ + Y + + Sbjct: 233 FLAHIYTELQLIEEALQKYQNLIDVGFSKSSYIVSQIAVAYHNIRDIDKALSIFNELRKQ 292 Query: 307 RPKG-------KDKLKVDELISSAIFHFKAAMERDSMFAFAYTDLANMYAEGGQYSNAED 359 P + L V + S + E D + N Y+ Q+ A Sbjct: 293 DPYRIENMDTFSNLLYVRSMKSELSYLAHNLCEIDKYRVETCCVIGNYYSLRSQHEKAAL 352 Query: 360 IFRKALRLENITDDHKHQIHYHYGRFQEFHRKSENTAIHHYLEALKVKDRSPLRTKLTSA 419 F++AL+L + + Y K+ + AI Y A++V R Sbjct: 353 YFQRALKLNPRYLGAWTLMGHEY-----MEMKNTSAAIQAYRHAIEVNKR---------- 397 Query: 420 LKKLSTKRLCHNALDVQSLSALGFVYKLEGEKRQAAEYYEKAQKIDPENAEFLTALCE 477 D ++ LG Y++ YY +A ++ P ++ L AL E Sbjct: 398 --------------DYRAWYGLGQTYEILKMPFYCLYYYRRAHQLRPNDSRMLVALGE 441 Score = 32.4 bits (72), Expect = 0.40, Method: Composition-based stats. Identities = 24/126 (19%), Positives = 44/126 (34%), Gaps = 7/126 (5%) Query: 154 KYYQKAKAAFEKALEVEPDNPEFNIGYAITVYRLDDSDREGSVKSFSLGPLRKAVTLNPD 213 K A A+ A+EV + G T L + + L R+A L P+ Sbjct: 379 KNTSAAIQAYRHAIEVNKRDYRAWYGLGQTYEILK-------MPFYCLYYYRRAHQLRPN 431 Query: 214 NSYIKVFLALKLQDVHAEAEGEKYIEEILDQISSQPYVLRYAAKFYRRKNSWNKALELLK 273 +S + V L + ++ E +K + L AK + + +A + Sbjct: 432 DSRMLVALGECYEKLNQLVEAKKCYWRAYAVGDVEKMALVKLAKLHEQLTESEQAAQCYI 491 Query: 274 KALEVT 279 K ++ Sbjct: 492 KYIQDI 497 >2GW1-A nrPDB Length = 514 Score = 48.2 bits (113), Expect = 8e-06, Method: Composition-based stats. Identities = 59/311 (18%), Positives = 116/311 (37%), Gaps = 32/311 (10%) Query: 156 YQKAKAAFEKALEVEPDNPEFNIGYAITVYRLDDSDREGSVKSFSLGPLRKAVTLNPD-N 214 + KA FE+ L+ ++ + AI++ + + ++KA+ L P N Sbjct: 212 FTKAARLFEEQLDKNNEDEKLKEKLAISLEHTGIFKFLKNDPLGAHEDIKKAIELFPRVN 271 Query: 215 SYIKVFLALKLQDVHAEAEGEKYIEEILDQISSQPYVLRYAAKFYRRKNSWNKALELLKK 274 SYI +AL + D + E Y ++ L S+ V + + ++++A + K Sbjct: 272 SYIY--MALIMADRNDSTEYYNYFDKALKLDSNNSSVYYHRGQMNFILQNYDQAGKDFDK 329 Query: 275 ALEVTPTSSFLHHQMGLCYRAQMIQIKKATHNRPKGKDKLKVDELISSAIFHFKAAMERD 334 A E+ P + F + Q+ ++K E + F A + Sbjct: 330 AKELDPENIFPYIQLACL---------------AYRENKFDDCETL------FSEAKRKF 368 Query: 335 SMFAFAYTDLANMYAEGGQYSNAEDIFRKALRLENITDDHKHQIHYHYGRFQEFHRKSEN 394 A + + + A + A+ LEN D I G+ R N Sbjct: 369 PEAPEVPNFFAEILTDKNDFDKALKQYDLAIELENKLDGIYVGIAPLVGKATLLTR---N 425 Query: 395 TAIHHYLEALK-VKDRSPLRTKLTSALKKLSTKRLCHNALDVQSLSAL---GFVYKLEGE 450 + +++EA ++ S L + A L+ +L +D ++++ + + E Sbjct: 426 PTVENFIEATNLLEKASKLDPRSEQAKIGLAQMKLQQEDID-EAITLFEESADLARTMEE 484 Query: 451 KRQAAEYYEKA 461 K QA + E A Sbjct: 485 KLQAITFAEAA 495 >5FZQ-A nrPDB Length = 131 Score = 47.4 bits (111), Expect = 1e-05, Method: Composition-based stats. Identities = 21/116 (18%), Positives = 50/116 (43%), Gaps = 3/116 (2%) Query: 187 LDDSDREGSVKSFSLGPLRKAVTLNPDNSYIKVFLALKLQDVHAEAEGEKYIEEILDQIS 246 L + + ++ +RKAV+L+P+N LA L E KY+ + + Sbjct: 11 LANLLAQEGKAEEAIKYMRKAVSLDPNNIKTLSNLANLLAQEGKAEEAIKYMRKAVSLDP 70 Query: 247 SQPYVLRYAAKFYRRKNSWNKALELLKKALEVTPTSS---FLHHQMGLCYRAQMIQ 299 + L A ++ +A++ ++KA+ + ++ LH ++++++ Sbjct: 71 NNIKTLSNLAVLLAQEGKAEEAIKYMRKAVSLIDKAAKGSTLHKNAAARRKSRLMR 126 Score = 42.1 bits (97), Expect = 6e-04, Method: Composition-based stats. Identities = 21/121 (17%), Positives = 43/121 (35%), Gaps = 5/121 (4%) Query: 220 FLALKLQDVHAEAEGEKYIEEILDQISSQPYVLRYAAKFYRRKNSWNKALELLKKALEVT 279 LA L E KY+ + + + L A ++ +A++ ++KA+ + Sbjct: 10 NLANLLAQEGKAEEAIKYMRKAVSLDPNNIKTLSNLANLLAQEGKAEEAIKYMRKAVSLD 69 Query: 280 PTSSFLHHQMGLCYRAQMIQIKKATHNRPKGKDKL-KVDELISSAIFHFKAAMERDSMFA 338 P + + + + Q KA + + +D+ + H AA R S Sbjct: 70 PNNIKTLSNLAVL----LAQEGKAEEAIKYMRKAVSLIDKAAKGSTLHKNAAARRKSRLM 125 Query: 339 F 339 Sbjct: 126 R 126 Score = 39.7 bits (91), Expect = 0.003, Method: Composition-based stats. Identities = 21/111 (18%), Positives = 41/111 (36%), Gaps = 5/111 (4%) Query: 321 SSAIFHFKAAMERDSMFAFAYTDLANMYAEGGQYSNAEDIFRKALRLENITDDHKHQIHY 380 AI + + A+ D ++LAN+ A+ G+ A RKA+ L+ + Sbjct: 22 EEAIKYMRKAVSLDPNNIKTLSNLANLLAQEGKAEEAIKYMRKAVSLDPNNIKTLSNLAV 81 Query: 381 HYGRFQEFHRKSENTAIHHYLEALKVKDRSPLRTKLTSALKKLSTKRLCHN 431 + + AI + +A+ + D++ + L RL Sbjct: 82 LLAQEGKAEE-----AIKYMRKAVSLIDKAAKGSTLHKNAAARRKSRLMRK 127 Score = 39.7 bits (91), Expect = 0.003, Method: Composition-based stats. Identities = 20/117 (17%), Positives = 42/117 (35%), Gaps = 21/117 (17%) Query: 251 VLRYAAKFYRRKNSWNKALELLKKALEVTPTSSFLHHQMGLCYRAQMIQIKKATHNRPKG 310 L A ++ +A++ ++KA+ + P + + Sbjct: 7 TLSNLANLLAQEGKAEEAIKYMRKAVSLDPNNIKTLSNLA-------------------- 46 Query: 311 KDKLKVDELISSAIFHFKAAMERDSMFAFAYTDLANMYAEGGQYSNAEDIFRKALRL 367 + L + AI + + A+ D ++LA + A+ G+ A RKA+ L Sbjct: 47 -NLLAQEGKAEEAIKYMRKAVSLDPNNIKTLSNLAVLLAQEGKAEEAIKYMRKAVSL 102 Score = 32.4 bits (72), Expect = 0.45, Method: Composition-based stats. Identities = 22/123 (17%), Positives = 46/123 (37%), Gaps = 29/123 (23%) Query: 342 TDLANMYAEGGQYSNAEDIFRKALRLENITDDHKHQIHYHYGRFQEFHRKSENTAIHHYL 401 ++LAN+ A+ G+ A RKA+ L+ + + + Sbjct: 9 SNLANLLAQEGKAEEAIKYMRKAVSLDPNNIKTLSNLANLLAQEGKAE------------ 56 Query: 402 EALKVKDRSPLRTKLTSALKKLSTKRLCHNALDVQSLSALGFVYKLEGEKRQAAEYYEKA 461 EA+K ++ + + ++++LS L + EG+ +A +Y KA Sbjct: 57 EAIKYMRKA-----------------VSLDPNNIKTLSNLAVLLAQEGKAEEAIKYMRKA 99 Query: 462 QKI 464 + Sbjct: 100 VSL 102 Score = 31.3 bits (69), Expect = 0.87, Method: Composition-based stats. Identities = 15/44 (34%), Positives = 25/44 (56%) Query: 435 VQSLSALGFVYKLEGEKRQAAEYYEKAQKIDPENAEFLTALCEL 478 +++LS L + EG+ +A +Y KA +DP N + L+ L L Sbjct: 5 IKTLSNLANLLAQEGKAEEAIKYMRKAVSLDPNNIKTLSNLANL 48 Score = 29.3 bits (64), Expect = 4.0, Method: Composition-based stats. Identities = 15/45 (33%), Positives = 26/45 (57%) Query: 434 DVQSLSALGFVYKLEGEKRQAAEYYEKAQKIDPENAEFLTALCEL 478 ++++LS L + EG+ +A +Y KA +DP N + L+ L L Sbjct: 38 NIKTLSNLANLLAQEGKAEEAIKYMRKAVSLDPNNIKTLSNLAVL 82 >6FO1-G nrPDB Length = 665 Score = 44.7 bits (104), Expect = 8e-05, Method: Composition-based stats. Identities = 55/332 (16%), Positives = 113/332 (34%), Gaps = 58/332 (17%) Query: 101 AWVYYHMDQLEEAQKYTGKIGNVCKKLSSPSNYKLECPETDCEKGWALLKFGGKY----- 155 AW +D++ + K + + LS S + + D +K L + G KY Sbjct: 92 AWAKLDVDRILDE---LDKDDSTHESLSQESESEEDGIHVDSQKALVLKEKGNKYFKQGK 148 Query: 156 YQKAKAAFEKALEVEPDNPEFNIGYAITVYRLDDSDREGSVKSFSLGPLRKAVTLNPDNS 215 Y +A + K ++ +P NP A +RL Sbjct: 149 YDEAIDCYTKGMDADPYNPVLPTNRASAYFRLKKF------------------------- 183 Query: 216 YIKVFLALKLQDVHAEAEGEKYIEEILDQISSQPYVLRYAAKFYRRKNSWNKALELLKKA 275 A AE + + L++ ++ Y R AA+F +K +A + ++ Sbjct: 184 --------------AVAESDCNLAVALNRSYTKAYSRRGAARFALQK--LEEAKKDYERV 227 Query: 276 LEVTPTSSFLHHQMGLCYRAQMIQIKKATHNRPKGKDKLKVDELISSAIFHFKAAMERDS 335 LE+ P + +++ +A A+ K+ V + +A +++ Sbjct: 228 LELEPNNFEATNELRKISQA------LASKENSYPKEADIVIKSTEGERKQIEA--QQNK 279 Query: 336 MFAFAYTDLANMYAEGGQYSNAEDIFRKALRLENITDDHKHQIHYHYGRFQEFHRKSENT 395 A + D N + + G+Y A + + + + + Y + Q++ ++E Sbjct: 280 QQAISEKDRGNGFFKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYE-EAEKD 338 Query: 396 AIHHYLEALKVKDRSPLRTKLTSALKKLSTKR 427 L R + L KL+ + Sbjct: 339 CTQAILLDGSYSKAFARRGTARTFLGKLNEAK 370 Score = 42.4 bits (98), Expect = 5e-04, Method: Composition-based stats. Identities = 40/289 (13%), Positives = 100/289 (34%), Gaps = 41/289 (14%) Query: 193 EGSVKSFSLGPLRKAVTLNPDNSYIKVFLALKL--QDVHAEAEGEKYIEEILDQISSQPY 250 + ++ K + +P N + A A AE + + L++ ++ Y Sbjct: 145 KQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAY 204 Query: 251 VLRYAAKFYRRKNSWNKALELLKKALEVTPTSSFLHHQMGLCYRAQMIQIKKATHNRPKG 310 R AA+F +K +A + ++ LE+ P + +++ +A A+ Sbjct: 205 SRRGAARFALQK--LEEAKKDYERVLELEPNNFEATNELRKISQA------LASKENSYP 256 Query: 311 KDKLKVDELISSAIFHFKAAMERDSMFAFAYTDLANMYAEGGQYSNAEDIFRKALRLENI 370 K+ V + +A +++ A + D N + + G+Y A + + + + + Sbjct: 257 KEADIVIKSTEGERKQIEA--QQNKQQAISEKDRGNGFFKEGKYERAIECYTRGIAADGA 314 Query: 371 TDDHKHQIHYHYGRFQEFHRKSENTAIHHYLEALKVKDRSPLRTKLTSALKKLSTKRLCH 430 Y + Q++ ++ + L Sbjct: 315 NALLPANRAMAYLKIQKYEEA----------------EKDCTQAILLD------------ 346 Query: 431 NALDVQSLSALGFVYKLEGEKRQAAEYYEKAQKIDPENAEFLTALCELR 479 ++ + G G+ +A + +E ++P N + +T L +++ Sbjct: 347 -GSYSKAFARRGTARTFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIK 394 >3JCM-G nrPDB Length = 899 Score = 44.0 bits (102), Expect = 1e-04, Method: Composition-based stats. Identities = 52/336 (15%), Positives = 114/336 (33%), Gaps = 36/336 (10%) Query: 146 WALLKFGGKYY---QKAKAAFEKALEVEPDNPEFNIGYA------ITVYRLDDSDREGSV 196 W+ LK + Y ++ A F++ L ++ + + +Y + + Sbjct: 516 WSRLKMATESYHKIEELLAFFQELLFQTKNSDDIRANMREKSPGLLMMYVSEYWKAQKGD 575 Query: 197 KSFSLGPLRKAVTLNPDNSYIKVFLALKLQDVHAEAEGEKYIEEILD-----QISSQPYV 251 +L + + + P N ++ F L E + ++ +IS + Sbjct: 576 TRQTLVLIDQIIDFAPHNLDLRFFKIKLLGRSLQLDELRDFFQQTFSSLEDFKISGTERL 635 Query: 252 LRYAAKFYRRKNSWNKALELL-KKALEVTPTSSFLHHQMGLCYRAQMIQIKKATHNRPKG 310 F R ++ +A++ L ++ L+ P Q+G Y M I+ + G Sbjct: 636 YYKYVNFLRYQDLNEEAIKFLNERCLKSFPICHKFFLQLGQIYH-SMGNIEMSRETYLSG 694 Query: 311 KDKLKVDELISSAIFHFKAAMERDSMFAFAYTDLANMYAEGGQYSNAEDIFRKALRLENI 370 + L+ ++ ++ + A + D G N +D+ + Sbjct: 695 TRLVPNCPLLWVSLSKIDEIDLKNPVRARSILD-------RGLLKNPDDV---------L 738 Query: 371 TDDHKHQIHYHYGRFQEFHRKSENTAIHHYLEA--LKVKDRSPLRTKLTSALKK-LSTKR 427 K Q+ G + A+ + L V+ + S+LKK + Sbjct: 739 FYIAKIQMEIRLGNLDQAELLV-TQALQKFPSNALLWVEQIKLFKHGNKSSLKKTIFQDA 797 Query: 428 LCHNALDVQSLSALGFVYKLEGEKRQAAEYYEKAQK 463 L D + L +G + E + + ++ E+A K Sbjct: 798 LRRTQNDHRVLLEIGVSFYAEAQYETSLKWLERALK 833 Score = 35.5 bits (80), Expect = 0.046, Method: Composition-based stats. Identities = 35/197 (17%), Positives = 66/197 (33%), Gaps = 26/197 (13%) Query: 193 EGSVKSFSLGPLRKAVTLNPDNSYIKVFLA-LKLQDVHAEAEGEKYIEEILDQISSQPYV 251 S L P+ + V L+ + D+ ++ L + V Sbjct: 680 SMGNIEMSRETYLSGTRLVPNCPLLWVSLSKIDEIDLKNPVRARSILDRGLLKNPD--DV 737 Query: 252 LRYAAKFYR--RKNSWNKALELLKKALEVTPTSSFLHHQMGLCYRAQMIQIKKATHNRPK 309 L Y AK R + ++A L+ +AL+ P+++ L + QIK H Sbjct: 738 LFYIAKIQMEIRLGNLDQAELLVTQALQKFPSNALL----------WVEQIKLFKHG--- 784 Query: 310 GKDKLKVDELISSAIFHFKAAMERDSMFAFAYTDLANMYAEGGQYSNAEDIFRKALRLEN 369 +K + + I F+ A+ R ++ + QY + +AL+ + Sbjct: 785 --NKSSLKKTI------FQDALRRTQNDHRVLLEIGVSFYAEAQYETSLKWLERALKKCS 836 Query: 370 ITDDHKHQIHYHYGRFQ 386 D + Y R Sbjct: 837 RYGDTWVWLFRTYARLG 853 >5OJF-A nrPDB Length = 314 Score = 43.2 bits (100), Expect = 2e-04, Method: Composition-based stats. Identities = 37/214 (17%), Positives = 77/214 (35%), Gaps = 28/214 (13%) Query: 174 PEFNIGYAI-----TVYRLDDSDREGSVKSFSLGPLRKAVTL--------NPDNSYIKVF 220 P + GY I T++ L ++ ++A+ +PD + + Sbjct: 16 PRGSGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNI 75 Query: 221 LALKLQDVHAEAEGEKYIEEILD--------QISSQPYVLRYAAKFYRRKNSWNKALELL 272 LAL +D + + + + L + L A Y ++ + +A L Sbjct: 76 LALVYRDQNKYKDAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLC 135 Query: 273 KKALEVTPTSSFLHHQMGLCYRAQMIQIKKATHNRPKGKDKLKVDELISSAIFHFKAAM- 331 K+ALE+ +G + Q+ +V+ A+ + + Sbjct: 136 KRALEIREKV------LGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYATRLG 189 Query: 332 ERDSMFAFAYTDLANMYAEGGQYSNAEDIFRKAL 365 D A +LA+ Y + G+Y +AE ++++ L Sbjct: 190 PDDPNVAKTKNNLASCYLKQGKYQDAETLYKEIL 223 Score = 34.3 bits (77), Expect = 0.11, Method: Composition-based stats. Identities = 29/124 (23%), Positives = 49/124 (39%), Gaps = 5/124 (4%) Query: 245 ISSQPYVLRYAAKFYRRKNSWNKALELLKKALEVTPTSSFLHHQMGLCYRAQMIQIKKAT 304 I ++ L Y + + A+ L K+ALE +S H A M+ I Sbjct: 24 IPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDH----PDVATMLNILALV 79 Query: 305 HNRPKGKDKLKVDELISSAIFHFKAAMERDSMFAFAYTDLANMYAEGGQYSNAEDIFRKA 364 + R + K K L + K + A +LA +Y + G+Y AE + ++A Sbjct: 80 Y-RDQNKYKDAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRA 138 Query: 365 LRLE 368 L + Sbjct: 139 LEIR 142 Score = 32.0 bits (71), Expect = 0.63, Method: Composition-based stats. Identities = 37/235 (15%), Positives = 75/235 (31%), Gaps = 23/235 (9%) Query: 51 LALYNLLAYVKHLKGQNKDALECLEQAEEIIQQEHSDKEEVRSLVTWGNYAWVYYHMDQL 110 + N+LA V + + KDA L A I+++ K+ T N A +Y + Sbjct: 70 ATMLNILALVYRDQNKYKDAAHLLNDALA-IREKTLGKDHPAVAATLNNLAVLYGKRGKY 128 Query: 111 EEAQKYTGKIGNVCKKLSSPSNYKLECPETDCEKGWALLKFGGKYYQKAKAAFEKALEV- 169 +EA+ + + +K+ + + ++ ALL ++ + + +ALE+ Sbjct: 129 KEAEPLCKRALEIREKVLGKFHPDVAKQLSNL----ALLCQNQGKAEEVEYYYRRALEIY 184 Query: 170 -------EPDNPEFNIGYAITVYRLDDSDREGSVKSFSLGPLRKAVTLNPDNSYIKVFL- 221 +P+ + A + ++ + N K Sbjct: 185 ATRLGPDDPNVAKTKNNLASCYLKQGKYQDAETLYK-EILTRAHEKEFGSVNGENKPIWM 243 Query: 222 --------ALKLQDVHAEAEGEKYIEEILDQISSQPYVLRYAAKFYRRKNSWNKA 268 K +D E + + + LR YRR+ A Sbjct: 244 HAEEREESKDKRRDSAPYGEYGSWYKACKVDSPTVNTTLRSLGALYRRQGKLEAA 298 >6FUZ-A nrPDB Length = 337 Score = 42.4 bits (98), Expect = 4e-04, Method: Composition-based stats. Identities = 29/164 (17%), Positives = 62/164 (37%), Gaps = 15/164 (9%) Query: 211 NPDNSYIKVFLALKLQDVHAEAEGEKYIEEIL--------DQISSQPYVLRYAAKFYRRK 262 +PD + + LAL +D + + + + L + L A Y ++ Sbjct: 51 HPDVATMLNILALVYRDQNKYKDAANLLNDALAIREKTLGRDHPAVAATLNNLAVLYGKR 110 Query: 263 NSWNKALELLKKALEVTPTSSFLHHQMGLCYRAQMIQIKKATHNRPKGKDKLKVDELISS 322 + +A L K+ALE+ +G + Q+ +V+ Sbjct: 111 GKYKEAEPLCKRALEIREKV------LGKDHPDVAKQLNNLALLCQNQGKYEEVEYYYQR 164 Query: 323 AIFHFKAAM-ERDSMFAFAYTDLANMYAEGGQYSNAEDIFRKAL 365 A+ ++ + D A +LA+ Y + G++ AE ++++ L Sbjct: 165 ALGIYQTKLGPDDPNVAKTKNNLASCYLKQGKFKQAETLYKEIL 208 Score = 39.4 bits (90), Expect = 0.004, Method: Composition-based stats. Identities = 29/165 (17%), Positives = 53/165 (32%), Gaps = 15/165 (9%) Query: 235 EKYIEEILDQISSQPYVLRYAAKFYRRKNSWNKALELLKKALEVTPTSSFLHHQMGLCYR 294 E + +L A YR +N + A LL AL + +G + Sbjct: 41 EDLEKTSGHDHPDVATMLNILALVYRDQNKYKDAANLLNDAL------AIREKTLGRDHP 94 Query: 295 AQMIQIKK-ATHNRPKGKDKLKVDELISSAIFHFKAAMERDSMFAFAYTDLANMYAEGGQ 353 A + A +GK K + K + A +LA + G+ Sbjct: 95 AVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGK 154 Query: 354 YSNAEDIFRKALRL--------ENITDDHKHQIHYHYGRFQEFHR 390 Y E +++AL + + K+ + Y + +F + Sbjct: 155 YEEVEYYYQRALGIYQTKLGPDDPNVAKTKNNLASCYLKQGKFKQ 199 Score = 31.3 bits (69), Expect = 1.1, Method: Composition-based stats. Identities = 35/233 (15%), Positives = 82/233 (35%), Gaps = 29/233 (12%) Query: 51 LALYNLLAYVKHLKGQNKDALECLEQA----EEIIQQEHSDKEEVRSLVTWGNYAWVYYH 106 + N+LA V + + KDA L A E+ + ++H T N A +Y Sbjct: 55 ATMLNILALVYRDQNKYKDAANLLNDALAIREKTLGRDHPAVA-----ATLNNLAVLYGK 109 Query: 107 MDQLEEAQKYTGKIGNVCKKLSSPSNYKLECPETDCEKGWALLKFGGKYYQKAKAAFEKA 166 + +EA+ + + +K+ + + ALL Y++ + +++A Sbjct: 110 RGKYKEAEPLCKRALEIREKVLGKDHPDV----AKQLNNLALLCQNQGKYEEVEYYYQRA 165 Query: 167 LEV--------EPDNPEFNIGYAITVYRLDDSDREGSVKSFSLGPL--RKAVTLNPDNSY 216 L + +P+ + A + + ++ L R+ +++ +N Sbjct: 166 LGIYQTKLGPDDPNVAKTKNNLASCYLKQGKFKQAETLYKEILTRAHEREFGSVDDENKP 225 Query: 217 IKVFLALKLQDVHAEAEGEKY------IEEILDQISSQPYVLRYAAKFYRRKN 263 I + + + + +G + + + L+ YRR+ Sbjct: 226 IWMHAEEREECKGKQKDGSAFGEYGGWYKACKVDSPTVTTTLKNLGALYRRQG 278 >6AF0-A nrPDB Length = 939 Score = 42.1 bits (97), Expect = 5e-04, Method: Composition-based stats. Identities = 65/415 (15%), Positives = 148/415 (35%), Gaps = 49/415 (11%) Query: 66 QNKDALECLEQAEEIIQQEHSDKEEVRSLVTWGNYAWVYYHMDQLEEAQKYTGKIGNVCK 125 Q ++AL+ E+A + Q R+++ A + + + E+ +V Sbjct: 173 QLRNALKSFEEAIRVSQG--------RNMLAVMGKARALFSLGRYPES---LAAYQDVVA 221 Query: 126 KLSSPSNYKLECPETDCEKGWALLKFGGKYYQKAKAAFEKALEVEPDNPEFNIGYAITVY 185 K+ + P+ G + G K AK A+E+ LE+ PD+ + + +Y Sbjct: 222 KM-----PDMVDPDPRIGIGCCFWQLGFK--DDAKIAWERCLEINPDSK--HANILLGLY 272 Query: 186 RLDDSDREGSVKSFSLGPLRKAV--------TLNPDNSYIKVFLALKLQDVHAEAEGEKY 237 LD S + + +KA+ L+ + A + Sbjct: 273 YLDASGHVPTNSPEFIRLYKKAMTEYTQKSFKLDKNLPLTCATFAGYFLSRKQFGNVDAL 332 Query: 238 IEEILDQISSQP---YVLRYAAKFYRRKNSWNKALELLKKALEVT--PTSSFLHHQMGLC 292 + + A+ + +A + ++A + +L + G Sbjct: 333 AHKAIQYTDVNAIASDGWYLLARKEHYDGNLERASDYYRRADDARGGAERGYLPAKFGA- 391 Query: 293 YRAQMIQIKKATHNRPKGKDKLKVDELISSAIFHFKAAMERDSMFAFAYTDLANMYAEGG 352 AQ+ +K G+ KL+++++I + +++A + +++A + + Sbjct: 392 --AQLSVLKNDL-----GEAKLRLEKMIQHS-KNYEAMILLGTLYAEEVFANQSAAVKED 443 Query: 353 QYSNAEDIFRKALRLENITDDHKHQI----HYHYGRFQEFHRKSENTAIH--HYLEALKV 406 + + A+ + + D K + + + +S + A+ +E L++ Sbjct: 444 KSAEAKKAISLLEGVRSAWKDPKRNLSPDAAVLLNLARLYESESPDKALQCLQQVEQLEI 503 Query: 407 KDRSPLRTKLTSALKKLSTKRLCHNALDVQSLSALGFVYKLEGEKRQAAEYYEKA 461 P A + + + L Q L+ +G Y EG+ R A E+++ A Sbjct: 504 DQI-PQSEYPPDAEDEAAARAAIRKLLPPQLLNNIGCFYSQEGKHRLATEFFQAA 557 Score = 38.2 bits (87), Expect = 0.007, Method: Composition-based stats. Identities = 24/115 (20%), Positives = 49/115 (42%), Gaps = 21/115 (18%) Query: 260 RRKNSWNKALELLKKALEVTPTSSFLHHQMGLCYRAQMIQIKKATHNRPKGKDKLKVDEL 319 +R ++N+A+E KAL++ P +++ + + +R K+ L++ Sbjct: 716 KRSAAYNRAVEFFDKALQLDPKNAYAAQGIAIA----------LVEDRKDYKNALQIFIK 765 Query: 320 ISSAIFHFKAAMERDSMFAFAYTDLANMYAEGGQYSNAEDIFRKALRLENITDDH 374 + I A Y ++ ++YAE Q+S A + + AL E +D Sbjct: 766 VRETIQD-----------AHVYVNMGHIYAELRQFSKAIESYEIALSKEGKANDA 809 Score = 37.8 bits (86), Expect = 0.010, Method: Composition-based stats. Identities = 25/151 (16%), Positives = 59/151 (39%), Gaps = 10/151 (6%) Query: 156 YQKAKAAFEKALEVEPDNPEFNIGYAITVYRLDDSDREGSVKSFSLGPLRKAVTLNPDNS 215 Y +A F+KAL+++P N G AI + ++D + + V ++ Sbjct: 721 YNRAVEFFDKALQLDPKNAYAAQGIAIAL--VEDRKDYKNALQIFI-----KVRETIQDA 773 Query: 216 YIKVFLALKLQDVHAEAEGEKYIEEILDQISSQPY--VLRYAAKFYRRKNSWNKALELLK 273 ++ V + ++ ++ + E L + ++ + + K + L+ K Sbjct: 774 HVYVNMGHIYAELRQFSKAIESYEIALSKEGKANDAGIISCLGRTWLNKGRAERNLDAYK 833 Query: 274 KALEVTPTS-SFLHHQMGLCYRAQMIQIKKA 303 AL+ + + Q+ + +QI+ A Sbjct: 834 MALDQAKKAVAVAPDQLHFKFNVAFVQIQIA 864 >5OJ8-A nrPDB Length = 255 Score = 41.7 bits (96), Expect = 7e-04, Method: Composition-based stats. Identities = 29/164 (17%), Positives = 62/164 (37%), Gaps = 15/164 (9%) Query: 211 NPDNSYIKVFLALKLQDVHAEAEGEKYIEEILD--------QISSQPYVLRYAAKFYRRK 262 +PD + + LAL +D + + + + L + L A Y ++ Sbjct: 88 HPDVATMLNILALVYRDQNKYKDAANLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKR 147 Query: 263 NSWNKALELLKKALEVTPTSSFLHHQMGLCYRAQMIQIKKATHNRPKGKDKLKVDELISS 322 + +A L K+ALE+ +G + Q+ +V+ Sbjct: 148 GKYKEAEPLCKRALEIREKV------LGKDHPDVAKQLNNLALLCQNQGKYEEVEYYYQR 201 Query: 323 AIFHFKAAM-ERDSMFAFAYTDLANMYAEGGQYSNAEDIFRKAL 365 A+ ++ + D A +LA+ Y + G++ AE ++++ L Sbjct: 202 ALEIYQTKLGPDDPNVAKTKNNLASCYLKQGKFKQAETLYKEIL 245 Score = 39.7 bits (91), Expect = 0.003, Method: Composition-based stats. Identities = 29/165 (17%), Positives = 53/165 (32%), Gaps = 15/165 (9%) Query: 235 EKYIEEILDQISSQPYVLRYAAKFYRRKNSWNKALELLKKALEVTPTSSFLHHQMGLCYR 294 E + +L A YR +N + A LL AL + +G + Sbjct: 78 EDLEKTSGHDHPDVATMLNILALVYRDQNKYKDAANLLNDAL------AIREKTLGKDHP 131 Query: 295 AQMIQIKK-ATHNRPKGKDKLKVDELISSAIFHFKAAMERDSMFAFAYTDLANMYAEGGQ 353 A + A +GK K + K + A +LA + G+ Sbjct: 132 AVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGK 191 Query: 354 YSNAEDIFRKALRL--------ENITDDHKHQIHYHYGRFQEFHR 390 Y E +++AL + + K+ + Y + +F + Sbjct: 192 YEEVEYYYQRALEIYQTKLGPDDPNVAKTKNNLASCYLKQGKFKQ 236 >5NNP-A nrPDB Length = 745 Score = 41.3 bits (95), Expect = 9e-04, Method: Composition-based stats. Identities = 41/239 (17%), Positives = 74/239 (30%), Gaps = 28/239 (11%) Query: 206 KAVTLNPDNSYIKVFLALKLQDVHAEAEGEKYIEEILDQISSQPYVLRYAAKFYRRKNSW 265 + + NP + AL L E +E L YR ++ Sbjct: 35 QILKKNPKHGDTMSMKALILNAQGKTEEAFALAKEALTIDMKSYICWHVYGILYRTNKNF 94 Query: 266 NKALELLKKALEVTPTSSFLHHQMGLCYRAQMIQIKKATHNRPKGKDKLKVDELISSAIF 325 ++A++ K AL++ P S + + ++QI + + +L + Sbjct: 95 DEAIKAYKFALKLEPESHQIQRDLA------VLQI-QMRDYAGYVQSRLNM--------- 138 Query: 326 HFKAAMERDSMFAFAYTDLANMYAEGGQYSNAEDI---FRKALRLENITDDHKHQIHYHY 382 ++ +T LA Y G AE I + K+L D +H Y Sbjct: 139 -----LKARPQIRQNWTALAIAYHLEGNLEKAEHILTTYEKSLTTPPPKTDLEHSEALLY 193 Query: 383 GRFQEFHRKSENTAIHHYLEALKVKDRSPLRTKLTSALKKLSTKRLCHNALDVQSLSAL 441 R A+ H L+ + L L+ +L ++ AL Sbjct: 194 KNTIIAERGDIERALQH----LETDCKHCLDRLAVMELRASYLSKLARKDEAAKAYRAL 248 Score = 37.0 bits (84), Expect = 0.019, Method: Composition-based stats. Identities = 55/362 (15%), Positives = 122/362 (33%), Gaps = 63/362 (17%) Query: 142 CEKGWALLKFGGKYYQKAKAAFEKALEVEPDNPEFNIGYAITVYRLDDSDREGSVKSFSL 201 C + +L K + +A A++ AL++EP++ + A+ ++ D + ++ Sbjct: 80 CWHVYGILYRTNKNFDEAIKAYKFALKLEPESHQIQRDLAVLQIQMRDYAGYVQSR-LNM 138 Query: 202 GPLRKAVTLNPDNSYIKVFLALKLQDVHAEAEGEKY---IEEILDQISSQPYVLRYAAKF 258 R + N LA+ + E E+ L + + A Sbjct: 139 LKARPQIRQN------WTALAIAYHLEGNLEKAEHILTTYEKSLTTPPPKTDLEHSEALL 192 Query: 259 YR-----RKNSWNKALELLKKALEVTPTSSFLHHQMGLCYRAQMIQIKKATHNRPKGKDK 313 Y+ + +AL+ L+ + R +++++ + ++ KD Sbjct: 193 YKNTIIAERGDIERALQHLETDCKH------------CLDRLAVMELRASYLSKLARKD- 239 Query: 314 LKVDELISSAIFHFKAAMERDSMFAFAYTDLANMYAEGGQYSNAEDIFRKALRLENITDD 373 A ++A ++R+ Y L + A+ + D Sbjct: 240 --------EAAKAYRALLDRNPEHMDYYKGLISALDISADDEEAQKAVYDEYAAKYPRSD 291 Query: 374 HKHQIHYHYGRFQEFHRKSE---------------NTAIHHYLEALKVKDRSPLRTKLTS 418 ++ ++ + F ++ H Y ++ K + + L + Sbjct: 292 AAKRLPLNFLSGERFRTTAKAYLTLMFDKGVPSTFANLKHLYSDSFKKETLASLAEEY-- 349 Query: 419 ALKKLSTKRLCHNALDVQ-------SLSALG--FVYKLEGEKRQAAEYYEKAQKIDPENA 469 L + R N D +L L + Y + + +A EY EKA ++DP+N Sbjct: 350 -LNEYVNARPSDNQADGDGSKGKGAALYYLAQHYNYYMSRDLTRALEYVEKAIELDPKNV 408 Query: 470 EF 471 +F Sbjct: 409 DF 410 Score = 33.6 bits (75), Expect = 0.21, Method: Composition-based stats. Identities = 17/70 (24%), Positives = 29/70 (41%) Query: 200 SLGPLRKAVTLNPDNSYIKVFLALKLQDVHAEAEGEKYIEEILDQISSQPYVLRYAAKFY 259 +L + KA+ L+P N + A + A+ + ++ Y+ AAK+ Sbjct: 393 ALEYVEKAIELDPKNVDFHMTKARIFKHQGDLAKAAETMDYARSLDPKDRYINSKAAKYQ 452 Query: 260 RRKNSWNKAL 269 R N KAL Sbjct: 453 LRNNENEKAL 462 Score = 32.0 bits (71), Expect = 0.63, Method: Composition-based stats. Identities = 34/174 (19%), Positives = 60/174 (34%), Gaps = 22/174 (12%) Query: 313 KLKVDELISSAIFHFKAAMERDSMFAFAYTDLANMYAEGGQYSNAEDIFRKALRLENITD 372 + D+ + + ++++ + A + G+ A AL E +T Sbjct: 19 RHYEDKQYKRGLKAAEQILKKNPKHGDTMSMKALILNAQGKTEEAF-----ALAKEALTI 73 Query: 373 DHKHQIHYHYGRFQEFHRKSENTAIHHYLEALKVKDRS------------PLRTKLTSAL 420 D K I +H K+ + AI Y ALK++ S +R Sbjct: 74 DMKSYICWHVYGILYRTNKNFDEAIKAYKFALKLEPESHQIQRDLAVLQIQMRDYAGYVQ 133 Query: 421 KKLSTKRLCHNALDVQSLSALGFVYKLEGEKRQAAE---YYEKAQKIDPENAEF 471 +L+ + Q+ +AL Y LEG +A YEK+ P + Sbjct: 134 SRLNMLKARPQI--RQNWTALAIAYHLEGNLEKAEHILTTYEKSLTTPPPKTDL 185 >3ZFW-A nrPDB Length = 263 Score = 41.3 bits (95), Expect = 9e-04, Method: Composition-based stats. Identities = 30/164 (18%), Positives = 62/164 (37%), Gaps = 15/164 (9%) Query: 211 NPDNSYIKVFLALKLQDVHAEAEGEKYIEEILD--------QISSQPYVLRYAAKFYRRK 262 +PD + + LAL +D + + + + L + L A Y ++ Sbjct: 19 HPDVATMLNILALVYRDQNKYKDAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKR 78 Query: 263 NSWNKALELLKKALEVTPTSSFLHHQMGLCYRAQMIQIKKATHNRPKGKDKLKVDELISS 322 + +A L K+ALE+ +G + Q+ +V+ Sbjct: 79 GKYKEAEPLCKRALEIREKV------LGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRR 132 Query: 323 AIFHFKAAM-ERDSMFAFAYTDLANMYAEGGQYSNAEDIFRKAL 365 A+ + + D A +LA+ Y + G+Y +AE ++++ L Sbjct: 133 ALEIYATRLGPDDPNVAKTKNNLASCYLKQGKYQDAETLYKEIL 176 Score = 30.5 bits (67), Expect = 1.5, Method: Composition-based stats. Identities = 37/235 (15%), Positives = 75/235 (31%), Gaps = 23/235 (9%) Query: 51 LALYNLLAYVKHLKGQNKDALECLEQAEEIIQQEHSDKEEVRSLVTWGNYAWVYYHMDQL 110 + N+LA V + + KDA L A I+++ K+ T N A +Y + Sbjct: 23 ATMLNILALVYRDQNKYKDAAHLLNDALA-IREKTLGKDHPAVAATLNNLAVLYGKRGKY 81 Query: 111 EEAQKYTGKIGNVCKKLSSPSNYKLECPETDCEKGWALLKFGGKYYQKAKAAFEKALEV- 169 +EA+ + + +K+ + + ++ ALL ++ + + +ALE+ Sbjct: 82 KEAEPLCKRALEIREKVLGKFHPDVAKQLSNL----ALLCQNQGKAEEVEYYYRRALEIY 137 Query: 170 -------EPDNPEFNIGYAITVYRLDDSDREGSVKSFSLGPLRKAVTLNPDNSYIKVFL- 221 +P+ + A + ++ + N K Sbjct: 138 ATRLGPDDPNVAKTKNNLASCYLKQGKYQDAETLYK-EILTRAHEKEFGSVNGENKPIWM 196 Query: 222 --------ALKLQDVHAEAEGEKYIEEILDQISSQPYVLRYAAKFYRRKNSWNKA 268 K +D E + + + LR YRR+ A Sbjct: 197 HAEEREESKDKRRDSAPYGEYGSWYKACKVDSPTVNTTLRSLGALYRRQGKLEAA 251 >3NF1-A nrPDB Length = 311 Score = 41.3 bits (95), Expect = 0.001, Method: Composition-based stats. Identities = 29/164 (17%), Positives = 62/164 (37%), Gaps = 15/164 (9%) Query: 211 NPDNSYIKVFLALKLQDVHAEAEGEKYIEEILD--------QISSQPYVLRYAAKFYRRK 262 +PD + + LAL +D + + + + L + L A Y ++ Sbjct: 65 HPDVATMLNILALVYRDQNKYKDAANLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKR 124 Query: 263 NSWNKALELLKKALEVTPTSSFLHHQMGLCYRAQMIQIKKATHNRPKGKDKLKVDELISS 322 + +A L K+ALE+ +G + Q+ +V+ Sbjct: 125 GKYKEAEPLCKRALEIREKV------LGKDHPDVAKQLNNLALLCQNQGKYEEVEYYYQR 178 Query: 323 AIFHFKAAM-ERDSMFAFAYTDLANMYAEGGQYSNAEDIFRKAL 365 A+ ++ + D A +LA+ Y + G++ AE ++++ L Sbjct: 179 ALEIYQTKLGPDDPNVAKTKNNLASCYLKQGKFKQAETLYKEIL 222 Score = 39.4 bits (90), Expect = 0.004, Method: Composition-based stats. Identities = 29/165 (17%), Positives = 53/165 (32%), Gaps = 15/165 (9%) Query: 235 EKYIEEILDQISSQPYVLRYAAKFYRRKNSWNKALELLKKALEVTPTSSFLHHQMGLCYR 294 E + +L A YR +N + A LL AL + +G + Sbjct: 55 EDLEKTSGHDHPDVATMLNILALVYRDQNKYKDAANLLNDAL------AIREKTLGKDHP 108 Query: 295 AQMIQIKK-ATHNRPKGKDKLKVDELISSAIFHFKAAMERDSMFAFAYTDLANMYAEGGQ 353 A + A +GK K + K + A +LA + G+ Sbjct: 109 AVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGK 168 Query: 354 YSNAEDIFRKALRL--------ENITDDHKHQIHYHYGRFQEFHR 390 Y E +++AL + + K+ + Y + +F + Sbjct: 169 YEEVEYYYQRALEIYQTKLGPDDPNVAKTKNNLASCYLKQGKFKQ 213 Score = 33.6 bits (75), Expect = 0.19, Method: Composition-based stats. Identities = 36/229 (15%), Positives = 83/229 (36%), Gaps = 21/229 (9%) Query: 51 LALYNLLAYVKHLKGQNKDALECLEQAEEIIQQEHSDKEEVRSLVTWGNYAWVYYHMDQL 110 + N+LA V + + KDA L A I+++ K+ T N A +Y + Sbjct: 69 ATMLNILALVYRDQNKYKDAANLLNDALA-IREKTLGKDHPAVAATLNNLAVLYGKRGKY 127 Query: 111 EEAQKYTGKIGNVCKKLSSPSNYKLECPETDCEKGWALLKFGGKYYQKAKAAFEKALEV- 169 +EA+ + + +K+ + + ALL Y++ + +++ALE+ Sbjct: 128 KEAEPLCKRALEIREKVLGKDHPDV----AKQLNNLALLCQNQGKYEEVEYYYQRALEIY 183 Query: 170 -------EPDNPEFNIGYAITVYRLDDSDREGSVKSFSLGPL--RKAVTLNPDNSYIKVF 220 +P+ + A + + ++ L R+ +++ +N I + Sbjct: 184 QTKLGPDDPNVAKTKNNLASCYLKQGKFKQAETLYKEILTRAHEREFGSVDDENKPIWMH 243 Query: 221 LALKLQDVHAEAEGEKY------IEEILDQISSQPYVLRYAAKFYRRKN 263 + + + +G + + + L+ YRR+ Sbjct: 244 AEEREECKGKQKDGTSFGEYGGWYKACKVDSPTVTTTLKNLGALYRRQG 292 >6MFV-A nrPDB Length = 653 Score = 40.1 bits (92), Expect = 0.002, Method: Composition-based stats. Identities = 45/274 (16%), Positives = 99/274 (36%), Gaps = 35/274 (12%) Query: 213 DNSYIKVFLALKLQDVHAEAEGEKYIEEILDQISS--QPYVLRYAAKFYRRKNSWNKALE 270 DN Y K+ +A+ + K ++E + + + + A Y + KA Sbjct: 364 DNPYAKIEIAIIEVQRGLFEKAIKLLKEAEPYVDEFFKCEIYSWLADAYMELENLEKAER 423 Query: 271 LLKKALEVTPTSSFLHHQMGLCYRAQMIQIKKATHNRPKG-KDKLKVDELISSAIFHFKA 329 LKK E+ + ++ Y A+ + + N + K LK E+I K Sbjct: 424 YLKKTKEIVEKINDMYA--WFSYYAEKTKYEYYKENSREALKSALKELEIIR------KI 475 Query: 330 AMERDSMFAFAYTDLANMYAEGGQYSNAEDIFRKALRL------ENITDDHKHQIHYHYG 383 + + ++Y G Y +++AL++ + + ++ Y Sbjct: 476 GDPEKEGLVLLH--VGDIYLHMGNYEKGISYYQEALKMAKAYGIKFLEHISYMELAKGYY 533 Query: 384 RFQEFHRKSE--NTAIHHYL---------EALKVKDRSPLRTKLTSALKKLSTKRLCHNA 432 + + + + SE A +++L +A+ S + TK +K + + + Sbjct: 534 QLKLYEKASEYSEKAANYFLMIRNYRRATDAMAYGSVSYIATKNLEKAEKFAKEMIRIAQ 593 Query: 433 LDVQSLSALGFVYK-----LEGEKRQAAEYYEKA 461 L+ G+++ L+G+ + KA Sbjct: 594 STDYPLAWAGYIFLAAVDFLKGDDWREDYNLGKA 627 >5JZ6-A nrPDB Length = 429 Score = 39.0 bits (89), Expect = 0.005, Method: Composition-based stats. Identities = 34/182 (18%), Positives = 68/182 (37%), Gaps = 7/182 (3%) Query: 157 QKAKAAFEKALEVEPDNPEFNIGYAITVYRLDDSDREGSVKSFSLGPLRKAVTLNPDNSY 216 ++A AF++ + P +P G A L + R V ++ ++ +L PD Sbjct: 29 EEAVNAFKELVRKYPQSPRARYGKAQCEDDLAEKRRSNEVLRGAIETYQEVASL-PDVPA 87 Query: 217 IKVFLALKLQDVHAEAEGEK-----YIEEILDQISSQPYVLRYAAKFYRRKNSWNKALEL 271 + L+LK + + G ++ ++ + + Y + A ++ Sbjct: 88 DLLKLSLKRRSDRQQFLGHMRGSLLTLQRLVQLFPNDTSLKNDLGVGYLLIGDNDNAKKV 147 Query: 272 LKKALEVTPTSSFLHHQMGLCYRAQMIQIKKATHNRPKGKDKLKVDELISSAIFHFKAAM 331 ++ L VTP F G +AQ +I ++ +G + FH AM Sbjct: 148 YEEVLSVTPNDGFAKVHYGFILKAQN-KIAESIPYLKEGIESGDPGTDDGRFYFHLGDAM 206 Query: 332 ER 333 +R Sbjct: 207 QR 208 >4JHR-A nrPDB Length = 333 Score = 39.0 bits (89), Expect = 0.005, Method: Composition-based stats. Identities = 30/134 (22%), Positives = 50/134 (37%), Gaps = 19/134 (14%) Query: 339 FAYTDLANMYAEGGQYSNAEDIFRKALRLENITDDHKHQIHYHYGRFQEFHRKSE-NTAI 397 AY++L N Y G++ A + ++K L L D + Y + + AI Sbjct: 152 RAYSNLGNAYIFLGEFETASEYYKKTLLLARQLKDRAVEAQSCYSLGNTYTLLQDYEKAI 211 Query: 398 HHYLEALKVKDRSPLRTKLTSALKKLSTKRLCHNALDVQSLSALGFVYKLEGEKRQAAEY 457 ++L+ L + +L ++ R C S LG Y G QA + Sbjct: 212 DYHLKHLAIAQ------ELKD---RIGEGRAC--------WS-LGNAYTALGNHDQAMHF 253 Query: 458 YEKAQKIDPENAEF 471 EK +I E + Sbjct: 254 AEKHLEISREVGDL 267 >5MGX-E nrPDB Length = 290 Score = 37.8 bits (86), Expect = 0.010, Method: Composition-based stats. Identities = 18/127 (14%), Positives = 50/127 (39%), Gaps = 10/127 (7%) Query: 183 TVYRLDDSDREGSVKSFSLGPLRKAVTLNPDNSYIKVFLALKLQDVHAEAEGE---KYIE 239 Y+ D + ++ + + ++ L LK++ ++ A + + Sbjct: 140 AHYQRADFVLAANSYDLAIKAITSSAKVDMTFEEEAQLLQLKVKCLNNLAASQLKLDHYR 199 Query: 240 EILDQIS----SQPYVLRYA---AKFYRRKNSWNKALELLKKALEVTPTSSFLHHQMGLC 292 L S QP ++ K ++ +++A+ +L+ AL++ P++ +H ++ Sbjct: 200 AALRSCSLVLEHQPDNIKALFRKGKVLAQQGEYSEAIPILRAALKLEPSNKTIHAELSKL 259 Query: 293 YRAQMIQ 299 + Q Sbjct: 260 VKKHAAQ 266 Score = 29.7 bits (65), Expect = 3.0, Method: Composition-based stats. Identities = 22/76 (28%), Positives = 34/76 (44%), Gaps = 2/76 (2%) Query: 294 RAQMIQIKKATHNRPKGKDKLKVDELISSAIFHFKAAMERDSMFAFAYTDLANMYAEGGQ 353 AQ++Q+K N +LK+D +A+ +E A + A+ G+ Sbjct: 174 EAQLLQLKVKCLNNL-AASQLKLDHY-RAALRSCSLVLEHQPDNIKALFRKGKVLAQQGE 231 Query: 354 YSNAEDIFRKALRLEN 369 YS A I R AL+LE Sbjct: 232 YSEAIPILRAALKLEP 247 >5LJ5-S nrPDB Length = 687 Score = 37.8 bits (86), Expect = 0.012, Method: Composition-based stats. Identities = 43/233 (18%), Positives = 78/233 (33%), Gaps = 24/233 (10%) Query: 137 CPETDCEKGWALLKFGGKYYQKAKAAFEKALEVEPDNPEFNIGYAITVYRLDDSDREGSV 196 CP+ KG+ L+ K + + + +EK +E +P + + Y L D DR + Sbjct: 434 CPKAKTFKGYIELEVKLKEFDRVRKIYEKFIEFQPSDLQIWSQYGELEENLGDWDRVRGI 493 Query: 197 KSFSLGPLRKAVTLNPDNSYIKVFLALKLQDVHAEAEGEKYIEEILDQISSQPYVLRYAA 256 + +L N D L +KYI ++ A Sbjct: 494 YTIALDE-------NSDF----------LTKEAKIVLLQKYIT-----FETESQEFEKAR 531 Query: 257 KFYRRKNSWNKALELLKKALEVTPTSSFLHHQMGLCYRAQMIQIKKATHNRPKGKDKLKV 316 K YRR N+ + TS+ Q+ + Q + + ++KL+ Sbjct: 532 KLYRRYLELNQYSPQSWIEFAMYQTSTPTEQQLLDLAKLQSENVDEDIEFEITDENKLEA 591 Query: 317 DELISSAIFHFKAAMERDSMFA--FAYTDLANMYAEGGQYSNAEDIFRKALRL 367 ++ AI FK ++ + A D Y + F K ++ Sbjct: 592 RKVFEEAIVFFKEKDDKQGRLSILEALKDYEETYGTELDQETVKKRFPKVIKK 644 >5JJT-A nrPDB Length = 479 Score = 36.3 bits (82), Expect = 0.029, Method: Composition-based stats. Identities = 29/132 (21%), Positives = 51/132 (38%), Gaps = 21/132 (15%) Query: 247 SQPYVLRYAAKFYRRKNSWNKALELLKKALEVTPTSSFLHHQMGLCYRAQMIQIKKATHN 306 S+ + A + + ++ A++L KA+E+ ++ Y A N Sbjct: 7 SRAEEFKSQANEAFKGHKYSSAIDLYTKAIELNSNNAV--------YWA----------N 48 Query: 307 RPKGKDKLKVDELISSAIFHFKAAMERDSMFAFAYTDLANMYAEGGQYSNAEDIFRKALR 366 R KL E SAI A+E DS ++ Y Y G++ +A F++ R Sbjct: 49 RAFAHTKL---EEYGSAIQDASKAIEVDSRYSKGYYRRGAAYLAMGKFKDALKDFQQVKR 105 Query: 367 LENITDDHKHQI 378 L D ++ Sbjct: 106 LSPNDPDATRKL 117 Score = 30.5 bits (67), Expect = 1.6, Method: Composition-based stats. Identities = 20/120 (16%), Positives = 45/120 (37%), Gaps = 13/120 (10%) Query: 185 YRLDDSDREGSVK-SFSLGPLRKAVTLNPDNSYIKVFLALKLQDVHAEAEGEKYIEEILD 243 ++ ++ K S ++ KA+ LN +N+ A + + + ++ Sbjct: 12 FKSQANEAFKGHKYSSAIDLYTKAIELNSNNAVYWANRAFAHTKLEEYGSAIQDASKAIE 71 Query: 244 QISSQPYVLRYAAKFYRR------KNSWNKALELLKKALEVTPTSSFLHHQMGLCYRAQM 297 S RY+ +YRR + AL+ ++ ++P ++ C +A M Sbjct: 72 VDS------RYSKGYYRRGAAYLAMGKFKDALKDFQQVKRLSPNDPDATRKLKECEKAVM 125 >5DSE-A nrPDB Length = 837 Score = 35.9 bits (81), Expect = 0.037, Method: Composition-based stats. Identities = 26/151 (17%), Positives = 49/151 (32%), Gaps = 35/151 (23%) Query: 229 HAEAEGEKYIEEILDQISSQPYVLRYAAKFYRRKNSWNKALELLKKALEVTPTS------ 282 AE +E + VL + + S ++A ++AL ++PT Sbjct: 704 GKPAEATACTQEAANLFPMSHNVLYMRGQIAELRGSMDEARRWYEEALAISPTHVKSMQR 763 Query: 283 -SFLHHQMGLCYRAQMIQIKKATHNRPKGKDKLKVDELISSAIFHFKAAMERDSMFAFAY 341 + + HQ+G A+ I + A++ +S + Sbjct: 764 LALILHQLGRYSLAEKI----------------------------LRDAVQVNSTAHEVW 795 Query: 342 TDLANMYAEGGQYSNAEDIFRKALRLENITD 372 L + G + A + F AL LE + Sbjct: 796 NGLGEVLQAQGNDAAATECFLTALELEASSP 826 Score = 34.7 bits (78), Expect = 0.088, Method: Composition-based stats. Identities = 19/86 (22%), Positives = 35/86 (40%) Query: 200 SLGPLRKAVTLNPDNSYIKVFLALKLQDVHAEAEGEKYIEEILDQISSQPYVLRYAAKFY 259 +L ++A +L+P + +LAL+L E Y+ + L L A Sbjct: 494 ALLAFQRAHSLSPTDHQAAFYLALQLAISRQIPEALGYVRQALQLQGDDANSLHLLALLL 553 Query: 260 RRKNSWNKALELLKKALEVTPTSSFL 285 + ++ AL ++ AL P + L Sbjct: 554 SAQKHYHDALNIIDMALSEYPENFIL 579 Score = 34.7 bits (78), Expect = 0.095, Method: Composition-based stats. Identities = 77/393 (19%), Positives = 144/393 (36%), Gaps = 49/393 (12%) Query: 110 LEEAQKYTGKIGNVCKKLSS--PSNYKLECPETDCEKGWALLKFGGKYYQK-AKAAFEKA 166 LEEA+K+ + +V +K S Y + A L+ + Q+ A AF++A Sbjct: 442 LEEAEKFAKTVVDVGEKTSEFKAKGYLALGLTYSLQATDASLRGMQEVLQRKALLAFQRA 501 Query: 167 LEVEPDNPEFNIGYAITVYRLDDSDREGSVKSFSLGPLRKAVTLNPDNSYIKVFLALKLQ 226 + P + + + L +LG +R+A+ L D++ LAL L Sbjct: 502 HSLSPTDHQ-------AAFYLALQLAISRQIPEALGYVRQALQLQGDDANSLHLLALLLS 554 Query: 227 DVHAEAEGEKYIEEILDQISSQPYVLRYAAKFYRRKNSWNKALELLKKALEVT------- 279 + I+ L + +L K ++AL K L++ Sbjct: 555 AQKHYHDALNIIDMALSEYPENFILLFSKVKLQSLCRGPDEALLTCKHMLQIWKSCYNLT 614 Query: 280 -PTSSFLHHQMGLCYRAQMIQIKKAT----HNRPKGK------DKLKVDELISSAIFHF- 327 P+ S + A Q+ T + G +V++ +S Sbjct: 615 NPSDSGRGSSLLDRTIADRRQLNTITLPDFSDPETGSVHATSVAASRVEQALSEVASSLQ 674 Query: 328 KAAMERDSM-----FAFAYTDLANMYAEGGQYSNAEDIFRKALRLENITDDHKHQIHYHY 382 +A ++ + A + A +Y G+ + A ++A L ++ H + Y Sbjct: 675 SSAPKQGPLHPWMTLAQIWLHAAEVYIGIGKPAEATACTQEAANLFPMS----HNVLYMR 730 Query: 383 GRFQEFHRKSENTAIHHYLEALKVKD---RSPLRTKLT-SALKKLSTK-RLCHNALDV-- 435 G+ E R S + A Y EAL + +S R L L + S ++ +A+ V Sbjct: 731 GQIAEL-RGSMDEARRWYEEALAISPTHVKSMQRLALILHQLGRYSLAEKILRDAVQVNS 789 Query: 436 ---QSLSALGFVYKLEGEKRQAAEYYEKAQKID 465 + + LG V + +G A E + A +++ Sbjct: 790 TAHEVWNGLGEVLQAQGNDAAATECFLTALELE 822 Score = 32.0 bits (71), Expect = 0.51, Method: Composition-based stats. Identities = 16/82 (19%), Positives = 34/82 (41%) Query: 204 LRKAVTLNPDNSYIKVFLALKLQDVHAEAEGEKYIEEILDQISSQPYVLRYAAKFYRRKN 263 +A+ ++P + LAL L + + EK + + + S+ V + + + Sbjct: 747 YEEALAISPTHVKSMQRLALILHQLGRYSLAEKILRDAVQVNSTAHEVWNGLGEVLQAQG 806 Query: 264 SWNKALELLKKALEVTPTSSFL 285 + A E ALE+ +S + Sbjct: 807 NDAAATECFLTALELEASSPAV 828 >4KVO-A nrPDB Length = 731 Score = 35.5 bits (80), Expect = 0.047, Method: Composition-based stats. Identities = 40/256 (15%), Positives = 86/256 (33%), Gaps = 37/256 (14%) Query: 31 LFEVEDTIGQQLEFLTTKSRLALYNLLAYVKHLKGQNKDALECLEQAEEIIQQEHSDKEE 90 L +E + ++ FL T++ LY L +E+A+ I + Sbjct: 211 LLSIEKKVLDRVAFLETRAEYELY----------------LSKMEEAKSTIYLLLDRNPD 254 Query: 91 VRSLVTWGNYAWVYYHMDQLEEAQKYTGKIGNVCKKLSSPSNYKLECPETDCEKGWALLK 150 N+ + YY++ + + +GK+ + + L+ S P+++C L K Sbjct: 255 --------NHQY-YYNLQRAYGYEDASGKVLDSAEWLNLYSQLAKRYPKSECPTRLPLEK 305 Query: 151 FGGKYYQKAKAAFEKALEVEPDNPEFNIGYAITVYRLDDSDREGSVKS-----------F 199 G + + + +++ P + + S F Sbjct: 306 LEGDEFLTHVDLYLRK-KLKRGIPSVFVDVKSLYKDTKKCKVVEDLVSKYASSLSTTNKF 364 Query: 200 SLGPLRKAVTLNPDNSYIKVFLALKLQDVHAEAEGEKYIEEILDQISSQPYVLRYAAKFY 259 S + + + FLA V + EKY++ +D + + A+ Sbjct: 365 SEDDDNSQIEIPTTLLWTYYFLAQHFDHVGELEKAEKYVDLAIDHTPTLVELFMTKARIS 424 Query: 260 RRKNSWNKALELLKKA 275 + K A+E++ A Sbjct: 425 KHKGELQTAMEIMDHA 440 >5G04-X nrPDB Length = 599 Score = 35.5 bits (80), Expect = 0.059, Method: Composition-based stats. Identities = 39/271 (14%), Positives = 84/271 (30%), Gaps = 42/271 (15%) Query: 100 YAWVYYHMDQLEEAQKYTGKIGNVCKKLSSPSNYKLECPETDCEKGWALLKFGGKYYQKA 159 Y ++ +LE+ + ++ N+ + + P W + Y ++ Sbjct: 311 YGYLLAREGRLEDVENLGCRLFNISDQHAEP---------------WVVSGCHSFYSKR- 354 Query: 160 KAAFEKALEVEPDNPEFNIGYAITVYRLDDSDREGSVKSFSLGPLRKAVTLNPDNSYIKV 219 + +AL + + N + + R ++ R+A+ L P Sbjct: 355 ---YSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYE 411 Query: 220 FLALKLQDVHAEAEGEKYIEEILDQISSQPYVLRYAAKFYRRKN-SWNKALELLKKALEV 278 L ++ E + + + L A + KA LL KAL Sbjct: 412 GLIECYLASNSIREAMVMANNVYKTLGANAQTLTLLATVCLEDPVTQEKAKTLLDKALTQ 471 Query: 279 TPTSSFLHHQMGLCYRAQMIQIKKATHNRPKGKDKLKVDELISSAIFHFKAAMERDSMFA 338 P Y +++ + K +D + L+ +A+ + + Sbjct: 472 RPD-----------YIKAVVKKAELLSREQKYEDGI---ALLRNALANQSDCV------- 510 Query: 339 FAYTDLANMYAEGGQYSNAEDIFRKALRLEN 369 + L + +Y A D + AL L+ Sbjct: 511 -LHRILGDFLVAVNEYQEAMDQYSIALSLDP 540 Score = 35.1 bits (79), Expect = 0.069, Method: Composition-based stats. Identities = 44/275 (16%), Positives = 84/275 (30%), Gaps = 32/275 (11%) Query: 215 SYIKVFLALKLQDVHAEAEGEKYIEEILDQISSQPYVLRYAAKFYRRKNSWNKALELLKK 274 I + LA + E +E+L Q + + + Sbjct: 169 PKINMMLANLYKKAGQERPSVTSYKEVLRQCPLALDAILGLLSLSVKGAEV---ASMTMN 225 Query: 275 ALEVTPT--------SSFLHHQMGLCYRAQMIQIKKATHNRPKGKDKLKVDELISSAIFH 326 ++ P ++ G RA I K + VD L S A + Sbjct: 226 VIQTVPNLDWLSVWIKAYAFVHTGDNSRA----ISTICSLEKKSLLRDNVDLLGSLADLY 281 Query: 327 FKAAMERDSMFAFAYTDLANMYAEGGQYSNAEDIFRKALRLENITDDHKHQIHYHYGRFQ 386 F+A ++S+ F + + Y G D++ L E +D + Sbjct: 282 FRAGDNKNSVLKFEQAQMLDPYLIKG-----MDVYGYLLAREGRLED-VENLGCRLFNIS 335 Query: 387 EFHRKSENTAIHHYLEALKVKDRSPLRTKLTSALKKLSTKRLCHNALDVQSLSALGFVYK 446 + H + + H + + L K N+ VQ+L G + Sbjct: 336 DQHAEPWVVSGCHSFYSKRYSRALYLGAKAIQL-----------NSNSVQALLLKGAALR 384 Query: 447 LEGEKRQAAEYYEKAQKIDPENAEFLTALCELRLS 481 G ++A ++ +A ++ P + L E L+ Sbjct: 385 NMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYLA 419 Score = 29.3 bits (64), Expect = 3.5, Method: Composition-based stats. Identities = 57/340 (16%), Positives = 104/340 (30%), Gaps = 39/340 (11%) Query: 144 KGWALLKFGGKYYQKAKAAFEKALEVEPDNPEFNIGYAITVYRLDDSDREGSVKSFSLGP 203 K +A + G + + + DN + A +R D+ S+ Sbjct: 241 KAYAFVHTGDNSRAISTICSLEKKSLLRDNVDLLGSLADLYFRAGDNKN-------SVLK 293 Query: 204 LRKAVTLNPDNSYIKVFLALKLQDVHAEAEGEKYIEEILDQISSQ--PYVLRYAAKFYRR 261 +A L+P L + E + + P+V+ FY + Sbjct: 294 FEQAQMLDPYLIKGMDVYGYLLAREGRLEDVENLGCRLFNISDQHAEPWVVSGCHSFYSK 353 Query: 262 KNSWNKALELLKKALEVTPTSSFLHHQMGLCYRAQMIQIKKATHNRPKGKDKLKVDELIS 321 + S +AL L KA+++ S +A +++ + + Sbjct: 354 RYS--RALYLGAKAIQLNSNSV----------QALLLKGAALRNMGR-----------VQ 390 Query: 322 SAIFHFKAAMERDSMFAFAYTDLANMYAEGGQYSNAE---DIFRKALRLENITDDHKHQI 378 AI HF+ A+ Y L Y A + K L T + Sbjct: 391 EAIIHFREAIRLAPCRLDCYEGLIECYLASNSIREAMVMANNVYKTLGANAQTLTLLATV 450 Query: 379 HYHYGRFQEFHRKSENTAIHH---YLEALKVKDRSPLRTKLTSALKKLSTKRLCHNALDV 435 QE + + A+ Y++A+ VK L + + N D Sbjct: 451 CLEDPVTQEKAKTLLDKALTQRPDYIKAV-VKKAELLSREQKYEDGIALLRNALANQSDC 509 Query: 436 QSLSALGFVYKLEGEKRQAAEYYEKAQKIDPENAEFLTAL 475 LG E ++A + Y A +DP + + L + Sbjct: 510 VLHRILGDFLVAVNEYQEAMDQYSIALSLDPNDQKSLEGM 549 >5KHR-J nrPDB Length = 620 Score = 35.1 bits (79), Expect = 0.067, Method: Composition-based stats. Identities = 28/158 (17%), Positives = 54/158 (34%), Gaps = 14/158 (8%) Query: 213 DNSYIKVFLALKLQDVHAEAEGEKYIEEILDQISSQPYVLRYAAKFYRRKNSWNKALELL 272 + + L L + AE ++ + L P+V+ + W A + Sbjct: 368 HLPMLYIGLEYGLTNNSKLAE--RFFSQALSIAPEDPFVMHEVGVVAFQNGEWKTAEKWF 425 Query: 273 KKALEVTPTSSFLHHQMGLCYRAQMIQIKKATHNRPKGKDKLKVDELISSAIFHFKAAME 332 ALE + + + + +N KLK + A+ + + A+ Sbjct: 426 LDALEKIK---------AIGNEVTVDKWEPLLNNLGHVCRKLKKY---AEALDYHRQALV 473 Query: 333 RDSMFAFAYTDLANMYAEGGQYSNAEDIFRKALRLENI 370 A Y+ + +++ G + NA D F AL L Sbjct: 474 LIPQNASTYSAIGYIHSLMGNFENAVDYFHTALGLRRD 511 >5WQL-B nrPDB Length = 278 Score = 34.7 bits (78), Expect = 0.078, Method: Composition-based stats. Identities = 13/63 (20%), Positives = 23/63 (36%) Query: 229 HAEAEGEKYIEEILDQISSQPYVLRYAAKFYRRKNSWNKALELLKKALEVTPTSSFLHHQ 288 A + L P V Y + + +++ A E LE+ PT ++ H Sbjct: 60 GLRALARNDFSQALAIRPDMPEVFNYLGIYLTQAGNFDAAYEAFDSVLELDPTYNYAHLN 119 Query: 289 MGL 291 G+ Sbjct: 120 RGI 122 >4H7X-A nrPDB Length = 161 Score = 34.0 bits (76), Expect = 0.15, Method: Composition-based stats. Identities = 20/102 (19%), Positives = 39/102 (38%), Gaps = 16/102 (15%) Query: 191 DREGSVKSFS-------LGPLRKAVTLNPDNSY--------IKVFLALKLQDVHAEAEGE 235 E + S +G +A+ P + Y I+V A +L+ + + Sbjct: 22 KLEKNSVPLSDALLNKLIGRYSQAIEALPPDKYGQNESFARIQVRFA-ELKAIQEPDDAR 80 Query: 236 KYIEEILDQISSQPYVLRYAAKFYRRKNSWNKALELLKKALE 277 Y + +V A+F + + K+ +LL+KA+E Sbjct: 81 DYFQMARANCKKFAFVHISFAQFELSQGNVKKSKQLLQKAVE 122 >4B94-A nrPDB Length = 181 Score = 34.0 bits (76), Expect = 0.15, Method: Composition-based stats. Identities = 20/102 (19%), Positives = 39/102 (38%), Gaps = 16/102 (15%) Query: 191 DREGSVKSFS-------LGPLRKAVTLNPDNSY--------IKVFLALKLQDVHAEAEGE 235 E + S +G +A+ P + Y I+V A +L+ + + Sbjct: 13 KLEKNSVPLSDALLNKLIGRYSQAIEALPPDKYGQNESFARIQVRFA-ELKAIQEPDDAR 71 Query: 236 KYIEEILDQISSQPYVLRYAAKFYRRKNSWNKALELLKKALE 277 Y + +V A+F + + K+ +LL+KA+E Sbjct: 72 DYFQMARANCKKFAFVHISFAQFELSQGNVKKSKQLLQKAVE 113 >4ABN-A nrPDB Length = 474 Score = 34.0 bits (76), Expect = 0.16, Method: Composition-based stats. Identities = 37/282 (13%), Positives = 85/282 (30%), Gaps = 25/282 (8%) Query: 106 HMDQLEEAQKYTGKIGNVCKKLSSPSNYKLECPETDCEKGWALLKFGGKYYQKAKAAFEK 165 M + + +V +KL + +L C + ++ G K + EK Sbjct: 29 QMGRGSMMADEEEEAKHVLQKLQGLVD-RLYCFRDSYFETHSVEDAGRKQQD-VQEEMEK 86 Query: 166 ALEVEPDNPEFNIGYAITVYRLDD--SDREGSVKSFSLGPLRKAVTLNPDNSYIKVFLAL 223 L+ + + + L + + L KAV L P+ L Sbjct: 87 TLQ-QMEEVLGSAQVEAQALMLKGKALNVTPDYSPEAEVLLSKAVKLEPELVEAWNQLGE 145 Query: 224 KLQDVHAEAEGEKYIEEILDQISSQPYVLRYAAKFYR--RKNSWNK-------ALELLKK 274 L ++ L+ + R + +S ++ ++ K Sbjct: 146 VYWKKGDVTSAHTCFSGALTHCKNKV-SLQNLSMVLRQLQTDSGDEHSRHVMDSVRQAKL 204 Query: 275 ALEVTPTSSFLHHQMGLCYRAQMIQIKKATHNRPKGKDKLKVDELISSAIFHFKAAMERD 334 A+++ + +G Y + G++ + + SA + + Sbjct: 205 AVQMDVLDGRSWYILGNAYLSLYFNT---------GQNPKISQQAL-SAYAQAEKVDRKA 254 Query: 335 SMFAFAYTDLANMYAEGGQYSNAEDIFRKALRLENITDDHKH 376 S + + A ++ Y A + F +A L+ + + Sbjct: 255 SSNPDLHLNRATLHKYEESYGEALEGFSQAAALDPAWPEPQQ 296 >5O09-1C nrPDB Length = 238 Score = 33.6 bits (75), Expect = 0.23, Method: Composition-based stats. Identities = 39/202 (19%), Positives = 79/202 (39%), Gaps = 32/202 (15%) Query: 295 AQMIQIKKATHNRPKGKDKLKVDELISSAIFHFKAAMERDS-MFAFAYTDLANMYAEGGQ 353 A + QI R K D K + L A+F + ++D + Y+ LA++Y G+ Sbjct: 31 ALVEQISVLADLRQKEGDFRKAESLYREALFRAQELRKQDPDLLTGIYSLLAHLYDRWGR 90 Query: 354 YSNAEDIFRKALRL--ENITDDH------KHQIHYHYGRFQEFHR--------------- 390 A + + AL++ EN ++ K+ + + + ++F R Sbjct: 91 MDKAAEFYELALKISAENGLEESDKVATIKNNLAMIFKQLRKFERAEGYYCEALETFQRL 150 Query: 391 ----KSENTAIHHYLEALKVKDRSPLRTKLTSALKKLSTKRLCHNALD----VQSLSALG 442 + ++++ L L R ++ + L +D Q+ LG Sbjct: 151 DGEQSARVASVYNNLGVLYYSHMDVDRAQVMHERALAIRQNLHEGQMDPADLSQTFINLG 210 Query: 443 FVYKLEGEKRQAAEYYEKAQKI 464 VYK G+ ++A ++A++I Sbjct: 211 AVYKAAGDFQKAEACVDRAKRI 232 Score = 28.6 bits (62), Expect = 5.6, Method: Composition-based stats. Identities = 32/242 (13%), Positives = 76/242 (31%), Gaps = 35/242 (14%) Query: 151 FGGKYYQKAKAAFEKALEVEPDNPEFNIGYAITVYRLDDSDREGSVKSFSLGPLRKAV-- 208 + A + E+A + +P + L D ++ + R+A+ Sbjct: 3 ALERQIASASRSVEEARRLAYHDPIRVGALVEQISVLADLRQKEGDFRKAESLYREALFR 62 Query: 209 --TLNPDNSY----IKVFLALKLQDVHAEAEGEKYIEEILDQISSQ-------------- 248 L + I LA + ++ E L + Sbjct: 63 AQELRKQDPDLLTGIYSLLAHLYDRWGRMDKAAEFYELALKISAENGLEESDKVATIKNN 122 Query: 249 -PYVLRYAAKFYRRKNSWNKALELLKKAL-EVTPTSSFLHHQMGLCYRAQMIQIKKATHN 306 + + KF R + + +ALE ++ E + + +++ +G+ Y + M Sbjct: 123 LAMIFKQLRKFERAEGYYCEALETFQRLDGEQSARVASVYNNLGVLYYSHM----DVDRA 178 Query: 307 RPKGKDKLKVDELISSAIFHFKAAMERDSMFAFAYTDLANMYAEGGQYSNAEDIFRKALR 366 + + L + + + + + + +L +Y G + AE +A R Sbjct: 179 QVMHERALAIRQNLHEGQM-------DPADLSQTFINLGAVYKAAGDFQKAEACVDRAKR 231 Query: 367 LE 368 + Sbjct: 232 IR 233 >4ZLH-A nrPDB Length = 339 Score = 33.2 bits (74), Expect = 0.24, Method: Composition-based stats. Identities = 27/164 (16%), Positives = 54/164 (32%), Gaps = 35/164 (21%) Query: 323 AIFHFKAAMERDSMFAFAYTDLANMYAEGGQYSNAEDIFRKALRLENITDD----HKHQI 378 A+ F ++ D+ A+ L N++ G+ A I + + ++T + Q+ Sbjct: 4 AVDLFLDMLKEDTGTVEAHLTLGNLFRSRGEVDRAIRIHQTLMESASLTYEQRLLAIQQL 63 Query: 379 HYHYGRFQEFHRKSENTAIHHYLEALKVKDRSPLRTKLTSALKKLSTKRLCHNALDVQSL 438 Y + R + + AL++L Sbjct: 64 GRDYMAAGLYDRAEDM-----------FNQLTDETDFRIGALQQLLQ------------- 99 Query: 439 SALGFVYKLEGEKRQAAEYYEKAQKI--DPENAEFLTALCELRL 480 +Y+ E ++A + E+ K+ D + E CEL L Sbjct: 100 -----IYQATSEWQKAIDVAERLVKLGKDKQRVEIAHFYCELAL 138 >2C2L-A nrPDB Length = 281 Score = 32.8 bits (73), Expect = 0.30, Method: Composition-based stats. Identities = 32/140 (22%), Positives = 61/140 (43%), Gaps = 10/140 (7%) Query: 302 KATHNRPKGKDKLKVDELISSAIFHFKAAMERDSMFAFAYTDLANMYAEGGQYSNAEDIF 361 A + +G ++L V A + A+ R+ + A YT+ A Y + Q A Sbjct: 3 SAQELKEQG-NRLFVGRKYPEAAACYGRAITRNPLVAVYYTNRALCYLKMQQPEQALADC 61 Query: 362 RKALRLENITDDHKHQIHYHYGRFQEFHRKSENTAIHHYLEA--LKVKDRSPLRTKLTSA 419 R+AL L+ + H+ G+ Q +S + AI + A L + R + SA Sbjct: 62 RRALELDGQSVKA----HFFLGQCQ-LEMESYDEAIANLQRAYSLAKEQRLNFGDDIPSA 116 Query: 420 LKKLSTKRLCHNALDVQSLS 439 L +++ K+ N+++ + + Sbjct: 117 L-RIAKKK-RWNSIEERRIH 134 Score = 29.0 bits (63), Expect = 5.1, Method: Composition-based stats. Identities = 12/60 (20%), Positives = 20/60 (33%) Query: 233 EGEKYIEEILDQISSQPYVLRYAAKFYRRKNSWNKALELLKKALEVTPTSSFLHHQMGLC 292 E + + A Y + +AL ++ALE+ S H +G C Sbjct: 22 EAAACYGRAITRNPLVAVYYTNRALCYLKMQQPEQALADCRRALELDGQSVKAHFFLGQC 81 >5KYM-A nrPDB Length = 247 Score = 32.8 bits (73), Expect = 0.34, Method: Composition-based stats. Identities = 11/55 (20%), Positives = 23/55 (41%) Query: 229 HAEAEGEKYIEEILDQISSQPYVLRYAAKFYRRKNSWNKALELLKKALEVTPTSS 283 A G +E L +I + +RY + + + +A+ L++A+E Sbjct: 95 GFVATGAFIAKEELRKIPGVNWYIRYLNGVFLDRKNPRRAVRALREAIEKLKNGV 149 >4GN8-A nrPDB Length = 299 Score = 32.4 bits (72), Expect = 0.40, Method: Composition-based stats. Identities = 24/144 (16%), Positives = 51/144 (35%), Gaps = 6/144 (4%) Query: 331 MERDSMFAFAYTDLANMYAEGGQYSNAEDIF--RKALRLENITDDHKHQIHYHYGRFQEF 388 ++++ F D A Y G R L ++ DH + ++ Sbjct: 96 DKKNNRFNDGKVDPAGRYFAGTMAEETAPAVLERHQGSLYSLFPDHSVKKYFDQVDISNG 155 Query: 389 HRKSENTAIHHYLEALKVKDRSPLRTKLTSALKKLSTKRLCHNALDVQSLSALGFVYKLE 448 S + I +Y+++L + T ++S +R+ + + + G E Sbjct: 156 LDWSLDHKIFYYIDSLSYTVDAFDYDLQT---GQISNRRIVYKMEKDEQIPD-GMCIDAE 211 Query: 449 GEKRQAAEYYEKAQKIDPENAEFL 472 G+ A + ++DPE + L Sbjct: 212 GKLWVACYNGGRVIRLDPETGKRL 235 >5BT1-A nrPDB Length = 393 Score = 32.4 bits (72), Expect = 0.45, Method: Composition-based stats. Identities = 26/98 (26%), Positives = 44/98 (44%), Gaps = 13/98 (13%) Query: 322 SAIFHFKAAMERDSMFAFAYTDLAN---MYAEGGQYSNAEDIFRKALRL--------ENI 370 + +F A E D + +Y E Y NA D+ +AL L +++ Sbjct: 168 HELANFSPANEHDDEIEDVSQLRKSGFHIYFENDLYENALDLLAQALMLLGRPTADGQSL 227 Query: 371 TDDHKHQIHYHYGRFQEFHRKSE--NTAIHHYLEALKV 406 T++ + +I Y + R++E + AIHHYL+AL Sbjct: 228 TENSRLRIGDVYILMGDIEREAEMFSRAIHHYLKALGY 265 >2E54-A nrPDB Length = 385 Score = 32.4 bits (72), Expect = 0.45, Method: Composition-based stats. Identities = 15/92 (16%), Positives = 39/92 (42%), Gaps = 1/92 (1%) Query: 187 LDDSDREGSVKSFSLGPLRKAVTLNPDNSYIKVFLALKLQDVHAEAE-GEKYIEEILDQI 245 L++ + +G+ L +++ + D + + + ++ ++ + E K E L + Sbjct: 292 LEEVEEKGNYLMKKLQEMKEEYDVVADVRGMGLMIGIQFREEVSNREVATKCFENKLLVV 351 Query: 246 SSQPYVLRYAAKFYRRKNSWNKALELLKKALE 277 + +R+ + A+E LKK L+ Sbjct: 352 PAGNNTIRFLPPLTVEYGEIDLAVETLKKVLQ 383 >4UZY-A nrPDB Length = 651 Score = 32.4 bits (72), Expect = 0.48, Method: Composition-based stats. Identities = 27/158 (17%), Positives = 54/158 (34%), Gaps = 17/158 (10%) Query: 314 LKVDELISSAIFHFKAAMERDSMFAFAYTDLANMYAEGGQYSNAEDIFRKALRLENITDD 373 L ++ + AI H + ++ A + L Y GQY A ++ + + L +D Sbjct: 27 LIKEQKFAEAIQHLQYQLQNVPESRAALSLLGYCYYYTGQYDMASQMYEQLVTLYPSNED 86 Query: 374 HKHQIHYHYGRFQEFHRKSE--------NTAIHHYLEALKVKDRSPLRTKLTSALKKLST 425 +K + + S+ A+ L A + LT ++L Sbjct: 87 YKLYYAQSLYKGGMYPEASKAVVKVEGHQKAVTTLLVACSYEQ-----DDLTGCRRQLDK 141 Query: 426 KRLCHNALDVQSLSALGFVYKLEGEKRQAAEYYEKAQK 463 D ++ G + EG+ A + + A + Sbjct: 142 CA----PEDPDTMVNTGCIMFKEGKFEAARQKFNDAVQ 175 Score = 30.9 bits (68), Expect = 1.2, Method: Composition-based stats. Identities = 29/167 (17%), Positives = 58/167 (34%), Gaps = 27/167 (16%) Query: 155 YYQKAKAAFEKALEVEPDNPEFNIGYAITVYRLDDSDREGSVKSFSLGPLRKAV------ 208 Y A +E+ + + P N ++ + YA ++Y+ E S + +KAV Sbjct: 66 QYDMASQMYEQLVTLYPSNEDYKLYYAQSLYK-GGMYPEASKAVVKVEGHQKAVTTLLVA 124 Query: 209 ----------------TLNPDNSYIKVFLALKLQDVHAEAEGEKYIEEILDQISSQPYVL 252 P++ V + + + + + QP +L Sbjct: 125 CSYEQDDLTGCRRQLDKCAPEDPDTMVNTGCIMFKEGKFEAARQKFNDAVQALGYQPELL 184 Query: 253 RYAAKFYRRKNSWNKAL----ELLKKALEVTPTSSFLHHQMGLCYRA 295 A Y + + AL E+++KA+ P S + G+ R+ Sbjct: 185 YNIALCYYKTKQFGPALKHLAEIIEKAVREHPELSVGSNTDGMEVRS 231 >6C95-A nrPDB Length = 866 Score = 32.4 bits (72), Expect = 0.50, Method: Composition-based stats. Identities = 9/60 (15%), Positives = 25/60 (41%) Query: 216 YIKVFLALKLQDVHAEAEGEKYIEEILDQISSQPYVLRYAAKFYRRKNSWNKALELLKKA 275 +++ +LA + + +YI ++ + + AK Y+ + +A + +A Sbjct: 375 WVQYYLAQHYDKIGQPSIALEYINTAIESTPTLIELFLVKAKIYKHAGNIKEAARWMDEA 434 >6C87-A nrPDB Length = 452 Score = 31.7 bits (70), Expect = 0.72, Method: Composition-based stats. Identities = 23/95 (24%), Positives = 38/95 (40%), Gaps = 6/95 (6%) Query: 158 KAKAAFEKALEVEPDNPEFNIGYAITVYRLDDSDREGSVKSFSLGPLRKAVTLNPDNSYI 217 KAK + + +NP+ + G+ + +D + V + L AV L D+SY+ Sbjct: 148 KAKKLVSYLYDYDQNNPKTHQGFDCSKDTMDKIYKYYGVSEDTTDFLGHAVALYTDDSYM 207 Query: 218 KVFLALKLQDVHAEAEGEKYIEEILDQISSQPYVL 252 AL E + E+ L+ PYV Sbjct: 208 TTVPAL------EVIERMRLYEDSLNMYGKSPYVY 236 >4JA9-A nrPDB Length = 488 Score = 31.7 bits (70), Expect = 0.73, Method: Composition-based stats. Identities = 26/173 (15%), Positives = 59/173 (34%), Gaps = 33/173 (19%) Query: 248 QPYVLRYAAKFYRRKNSWNKALELLKKALEVTPTSSFLHHQMGLCYRAQMIQIKKATHNR 307 + L+ A Y + + A++ +A+E+ P+++ + L Y Sbjct: 16 RAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAY-------------- 61 Query: 308 PKGKDKLKVDELISSAIFHFKAAMERDSMFAFAYTDLANMYAEGGQYSNAEDIFRKALRL 367 E A+ A+E D + Y A G++ A + +++ Sbjct: 62 -------LRTECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKV 114 Query: 368 ENITDDHK----------HQIHYHYGRFQEFHRKSENTAIHHYLEALKVKDRS 410 + D K Q + + HR+S ++ +E++ ++D Sbjct: 115 KPNDKDAKMKYQECSKIVKQKAFERAIAGDEHRRSVVDSLD--IESMTIEDEY 165 >6AHD-N nrPDB Length = 941 Score = 31.3 bits (69), Expect = 1.0, Method: Composition-based stats. Identities = 14/98 (14%), Positives = 36/98 (36%) Query: 191 DREGSVKSFSLGPLRKAVTLNPDNSYIKVFLALKLQDVHAEAEGEKYIEEILDQISSQPY 250 + + + + + + P ++ + + L+ + + +E+ + P Sbjct: 719 EEQKEMMEKAREAYNQGLKKCPHSTPLWLLLSRLEEKIGQLTRARAILEKSRLKNPKNPG 778 Query: 251 VLRYAAKFYRRKNSWNKALELLKKALEVTPTSSFLHHQ 288 + + + R N A L+ KAL+ P S L + Sbjct: 779 LWLESVRLEYRAGLKNIANTLMAKALQECPNSGILWSE 816 Score = 30.5 bits (67), Expect = 1.6, Method: Composition-based stats. Identities = 37/227 (16%), Positives = 70/227 (30%), Gaps = 16/227 (7%) Query: 195 SVKSFSLGPLRKAVTLNPDNSYIKVFLALKLQDVHAEAEGEKYIEEILDQISSQPYVLRY 254 + + L+ NP + + A + I + + V Sbjct: 289 NDIKKARLLLKSVRETNPHHPPAWIASARLEEVTGKLQVARNLIMKGTEMCPKSEDVWLE 348 Query: 255 AAKFYRRKNSWNKALELLKKALEVTPTSSFLH---HQMGLCYRAQMIQIKKATHNRPKGK 311 AA+ + KA+ + +A+ P S ++ ++ RA+ ++KA + P Sbjct: 349 AARL--QPGDTAKAV--VAQAVRHLPQSVRIYIRAAELETDIRAKKRVLRKALEHVPNSV 404 Query: 312 DKLKVDELISS---AIFHFKAAMERDSMFAFAYTDLANMYAEGGQYSNAEDIFRKALRLE 368 K + A A+E + LA + Y NA + KA E Sbjct: 405 RLWKAAVELEEPEDARIMLSRAVECCPTSVELWLALARL----ETYENARKVLNKA--RE 458 Query: 369 NITDDHKHQIHYHYGRFQEFHRKSENTAIHHYLEALKVKDRSPLRTK 415 NI D I + + I + +L+ R + Sbjct: 459 NIPTDRHIWITAAKLEEANGNTQMVEKIIDRAITSLRANGVEINREQ 505 Score = 30.5 bits (67), Expect = 1.8, Method: Composition-based stats. Identities = 22/164 (13%), Positives = 50/164 (30%), Gaps = 12/164 (7%) Query: 143 EKGW---ALLKFGGKYYQKAKAAFEKALEVEPDNPEFNIGYAITVYRLDDSDREGSVKSF 199 E+ W L+ Y++A+ KA P A + + Sbjct: 642 EEIWLAAVKLESENDEYERARRLLAKARSSAPT--------ARVFMKSVKLEWVQDNIRA 693 Query: 200 SLGPLRKAVTLNPDNSYIKVFLALKLQDVHAEAEGEKYIEEILDQISSQPYVLRYAAKFY 259 + +A+ D + + + + + + L + + ++ Sbjct: 694 AQDLCEEALRHYEDFPKLWMMKGQIEEQKEMMEKAREAYNQGLKKCPHSTPLWLLLSRLE 753 Query: 260 RRKNSWNKALELLKKALEVTPTSSFLH-HQMGLCYRAQMIQIKK 302 + +A +L+K+ P + L + L YRA + I Sbjct: 754 EKIGQLTRARAILEKSRLKNPKNPGLWLESVRLEYRAGLKNIAN 797 >2CG3-A nrPDB Length = 658 Score = 31.3 bits (69), Expect = 1.0, Method: Composition-based stats. Identities = 28/136 (20%), Positives = 51/136 (37%), Gaps = 20/136 (14%) Query: 134 KLECPETDCEKGWALLKFGGKYYQKAKAAFEKAL--------EVEPDNPEFNIGYAITVY 185 +L P + ++ W + G A+A + L ++P +PE + G + Sbjct: 388 RLRLPPS-LDQEWYDRGYHGSVSHNARAVLNRYLGYYDGNPATLDPLSPEDSAGRYVEYM 446 Query: 186 RLDDSDREGSVKSFSLGPLRKAVTL-------NPDNSYIKVFLALKLQDVHAEAEGEKYI 238 + E + S++ G R V + PDN + A L+ + +AE + Sbjct: 447 GGAERLLEQARASYARGEYRWVVEVVNRLVFAEPDNRAARELQADALEQLGYQAENAGWR 506 Query: 239 EEILDQISSQPYVLRY 254 L S Y LR+ Sbjct: 507 NSYL----SAAYELRH 518 >3Q15-A nrPDB Length = 378 Score = 30.9 bits (68), Expect = 1.2, Method: Composition-based stats. Identities = 39/203 (19%), Positives = 76/203 (37%), Gaps = 32/203 (15%) Query: 291 LCYRAQMIQIKKATHNRPKGKDKLKVDELISSAIFHFKAAMERDSMFAFAYTDLANMYAE 350 +C+R Q++ + + G ++ V EL+ + + ++ + Y+ E Sbjct: 58 MCFRHQLM-LDYLEPGKTYG-NRPTVTELLET----IETPQKKLTGLLKYYSLFFRGMYE 111 Query: 351 GGQ--YSNAEDIFRKALRLENITDDHKHQIHYHY-GRFQEFHRKSENTAIHHYLEALKVK 407 Q Y A +R+A + D + +H+ +H K + +++H L+AL + Sbjct: 112 FDQKEYVEAIGYYREAEKELPFVSDDIEKAEFHFKVAEAYYHMKQTHVSMYHILQALDIY 171 Query: 408 DRSPL---------------RTKLTSALKKLSTKRLCHN-ALDVQ-------SLSALGFV 444 PL K L A+D+Q SL + Sbjct: 172 QNHPLYSIRTIQSLFVIAGNYDDFKHYDKALPHLEAALELAMDIQNDRFIAISLLNIANS 231 Query: 445 YKLEGEKRQAAEYYEKAQKIDPE 467 Y G+ + A E+++KA K+ E Sbjct: 232 YDRSGDDQMAVEHFQKAAKVSRE 254 >4GNB-A nrPDB Length = 299 Score = 30.9 bits (68), Expect = 1.3, Method: Composition-based stats. Identities = 24/144 (16%), Positives = 49/144 (34%), Gaps = 6/144 (4%) Query: 331 MERDSMFAFAYTDLANMYAEGGQYSNAEDIF--RKALRLENITDDHKHQIHYHYGRFQEF 388 ++++ F D A Y G R L ++ DH + ++ Sbjct: 96 DKKNNRFNDGKVDPAGRYFAGTMAEETAPAVLERHQGALYSLFPDHHVKKYFDQVDISNG 155 Query: 389 HRKSENTAIHHYLEALKVKDRSPLRTKLTSALKKLSTKRLCHNALDVQSLSALGFVYKLE 448 S + I +Y+++L S ++S +R + L+ + G E Sbjct: 156 LDWSLDHKIFYYIDSLSY---SVDAFDYDLQTGQISNRRSVYK-LEKEEQIPDGMCIDAE 211 Query: 449 GEKRQAAEYYEKAQKIDPENAEFL 472 G+ A + ++DP + L Sbjct: 212 GKLWVACYNGGRVIRLDPVTGKRL 235 >5AEM-A nrPDB Length = 447 Score = 30.9 bits (68), Expect = 1.4, Method: Composition-based stats. Identities = 12/74 (16%), Positives = 27/74 (36%) Query: 320 ISSAIFHFKAAMERDSMFAFAYTDLANMYAEGGQYSNAEDIFRKALRLENITDDHKHQIH 379 + AI+ F + + M + + +Y + GQ + A D F++ + ++ Sbjct: 93 VRQAIYCFSRVISLNPMEWESIYRRSMLYKKTGQLARALDGFQRLYMYNPYDANILRELA 152 Query: 380 YHYGRFQEFHRKSE 393 Y + E Sbjct: 153 ILYVDYDRIEDSIE 166 Score = 29.0 bits (63), Expect = 4.9, Method: Composition-based stats. Identities = 11/82 (13%), Positives = 25/82 (30%) Query: 195 SVKSFSLGPLRKAVTLNPDNSYIKVFLALKLQDVHAEAEGEKYIEEILDQISSQPYVLRY 254 ++ + ++LNP ++ + A + + +LR Sbjct: 91 DHVRQAIYCFSRVISLNPMEWESIYRRSMLYKKTGQLARALDGFQRLYMYNPYDANILRE 150 Query: 255 AAKFYRRKNSWNKALELLKKAL 276 A Y + ++EL K Sbjct: 151 LAILYVDYDRIEDSIELYMKVF 172 Score = 29.0 bits (63), Expect = 5.5, Method: Composition-based stats. Identities = 11/48 (22%), Positives = 20/48 (41%) Query: 340 AYTDLANMYAEGGQYSNAEDIFRKALRLENITDDHKHQIHYHYGRFQE 387 + LA Y E Y A++ + A++ E D + + Y R + Sbjct: 385 VFKPLARCYKEIESYETAKEFYELAIKSEPDDLDIRVSLAEVYYRLND 432 >1IHG-A nrPDB Length = 370 Score = 30.5 bits (67), Expect = 1.8, Method: Composition-based stats. Identities = 16/68 (23%), Positives = 31/68 (45%), Gaps = 1/68 (1%) Query: 222 ALKLQDVHAEAEGEKYIEEILDQISSQPYVLRYAAKFYRRKNSWNKALELLKKALEVTPT 281 A KL+ + + +E L+ S L A+ ++ +++AL LKKA E+ P Sbjct: 281 ACKLKMSDWQGAVDSCLE-ALEIDPSNTKALYRRAQGWQGLKEYDQALADLKKAQEIAPE 339 Query: 282 SSFLHHQM 289 + ++ Sbjct: 340 DKAIQAEL 347 >5OMP-A nrPDB Length = 462 Score = 30.1 bits (66), Expect = 2.5, Method: Composition-based stats. Identities = 34/179 (18%), Positives = 68/179 (37%), Gaps = 22/179 (12%) Query: 68 KDALECLEQAEEIIQQEHSDKEEVRSLVTWGNYAWVYYHMDQLEEAQKYTGKIGNVCKKL 127 + L+ E+A+E E KE++ VY+ + +A GKI + + Sbjct: 249 EVTLKSFEKAKE--SWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLE-- 304 Query: 128 SSPSNYKLECPETDCEKGWALLKFGG--------KYYQKAKAAFEKALEVEPDNPEFNIG 179 Y L E+ + + L F + Y KA +KAL ++ N + Sbjct: 305 ---MEYGLSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEK---- 357 Query: 180 YAITVYRLDDSDREGSVKSFSLGPLRKAVTLNPDNSYIKVFLALKLQDVHAEAEGEKYI 238 +YR ++ + + G K + +NP N ++ +++ + E ++ I Sbjct: 358 ---GLYRRGEAQLLMNEFESAKGDFEKVLEVNPQNKAARLQISMCQKKAKEHNERDRRI 413 >5XJC-J nrPDB Length = 848 Score = 29.7 bits (65), Expect = 3.0, Method: Composition-based stats. Identities = 17/70 (24%), Positives = 32/70 (45%) Query: 136 ECPETDCEKGWALLKFGGKYYQKAKAAFEKALEVEPDNPEFNIGYAITVYRLDDSDREGS 195 +CP+ K + L+ + + + + +EK LE P+N I +A L D DR + Sbjct: 602 KCPKNKLFKVYIELELQLREFDRCRKLYEKFLEFGPENCTSWIKFAELETILGDIDRARA 661 Query: 196 VKSFSLGPLR 205 + ++ R Sbjct: 662 IYELAISQPR 671 Score = 28.6 bits (62), Expect = 5.9, Method: Composition-based stats. Identities = 22/128 (17%), Positives = 53/128 (41%), Gaps = 8/128 (6%) Query: 154 KYYQKAKAAFEKALEVEPDNPEFNIGYAITVYRLDDSDREGSVKSFSLGPLRKAVTLNPD 213 K Q+A++ +E+AL+V+ N + YA + + ++ ++ L + Sbjct: 256 KEIQRARSIYERALDVDYRNITLWLKYAEMEMKNRQVNHARNIWDRAITTLPRVNQFWYK 315 Query: 214 NSYIKVFLALKLQDVHAEAEGEKYIEEILDQISSQPYVLRYAAKFYRRKNSWNKALELLK 273 +Y++ L A E+++E ++ + Y+ F R ++A + + Sbjct: 316 YTYMEEMLGNV---AGARQVFERWMEWQPEEQAWHSYI-----NFELRYKEVDRARTIYE 367 Query: 274 KALEVTPT 281 + + V P Sbjct: 368 RFVLVHPD 375 >5O6D-A nrPDB Length = 545 Score = 29.7 bits (65), Expect = 3.0, Method: Composition-based stats. Identities = 9/36 (25%), Positives = 21/36 (58%) Query: 59 YVKHLKGQNKDALECLEQAEEIIQQEHSDKEEVRSL 94 ++K +K ++ LE +++ E+++Q H + R L Sbjct: 386 FMKRVKTDDEVVLENIKRKEQLMQTIHQNSAGKRRL 421 >6FRK-r nrPDB Length = 605 Score = 29.3 bits (64), Expect = 4.0, Method: Composition-based stats. Identities = 53/300 (17%), Positives = 111/300 (37%), Gaps = 32/300 (10%) Query: 3 EIRKDTLKAILLELECHFTWNLLKEDIDLFEVEDTIGQQLEFLTTKSRLALYNLLA---- 58 E R + ++ L +E + ++ L E+ + +LE LA+Y L Sbjct: 88 EYRLNRIENALKTIE-----SANQQTDKLKELYGQVLYRLERYDE--CLAVYRDLVRNSQ 140 Query: 59 --YVKHLKGQNKDALECLEQAEEIIQQEHSDKEEVRSLVTWGNYAWVYYHMDQLEEAQKY 116 Y + K + E+++ + +E L N A QL +A K Sbjct: 141 DDYDEERKTNLSAVVAAQSNWEKVVPENLGLQEGTHELCY--NAACALIGQGQLSQAMKI 198 Query: 117 TGKIGNVCKK-LSSPSNYKLECPETDC----EKGWALLKFGGKYYQKAKAAFEKALEVEP 171 K ++C++ LS S+ E P+ + + +L+ G+ ++A + + ++++P Sbjct: 199 LQKAEDLCRRSLSEDSDGTEEDPQAELAIIHGQMAYILQLQGRT-EEALQLYNQIIKLKP 257 Query: 172 DNPEFNIGYAITVYRLDDSDREGSVKSFS---LGPLRKAVTLNPDNSYIKVFLALKLQDV 228 + A+ + +++ +V + V ++ K Sbjct: 258 TDV---GLLAVIANNIITINKDQNVFDSKKKVKLTNAEGVEFKLSKKQLQAIEFNKALLA 314 Query: 229 HAEAEGEKYIEEILDQISSQPY----VLRYAAKFYRRKNSWNKALELLKKALEVTPTSSF 284 + E+ + S P VL AA+ R K KA+ELL++ + P ++ Sbjct: 315 MYTNQAEQCRKISASLQSQSPEHLLPVLIQAAQLCREKQH-TKAIELLQEFSDQHPENAA 373 >3WCZ-A nrPDB Length = 308 Score = 28.6 bits (62), Expect = 5.7, Method: Composition-based stats. Identities = 16/78 (20%), Positives = 33/78 (42%), Gaps = 3/78 (3%) Query: 200 SLGPLRKAVTLNPDNSYIKVFLALKLQDVHAEAEGEKYIEEILDQISSQPYVLRYAAKFY 259 S+ +R+AV + Y + A QD +G I E + L K + Sbjct: 33 SIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG---IAEAIANGLVTREELFVTTKLW 89 Query: 260 RRKNSWNKALELLKKALE 277 K++ ++ + L+++L+ Sbjct: 90 NDKHARDQVVPALQESLK 107 >4HJH-A nrPDB Length = 481 Score = 28.6 bits (62), Expect = 5.8, Method: Composition-based stats. Identities = 15/63 (23%), Positives = 20/63 (31%), Gaps = 1/63 (1%) Query: 253 RYAAKFYRRKNSWNKALE-LLKKALEVTPTSSFLHHQMGLCYRAQMIQIKKATHNRPKGK 311 R KFYRR +K E + A P +G +Q + GK Sbjct: 114 RNGLKFYRRDGEIDKDDEAAISAAYRKLPAILAARKHVGSTETDAALQAYADRYAGFLGK 173 Query: 312 DKL 314 L Sbjct: 174 GSL 176 >6GIR-A nrPDB Length = 456 Score = 28.2 bits (61), Expect = 7.6, Method: Composition-based stats. Identities = 17/57 (29%), Positives = 26/57 (45%) Query: 36 DTIGQQLEFLTTKSRLALYNLLAYVKHLKGQNKDALECLEQAEEIIQQEHSDKEEVR 92 D +Q +F R L V LK + +DA E ++Q E+ Q + + EVR Sbjct: 39 DKEWRQRQFEVDSFRKEFNKLNKQVAQLKIKKEDASEIIQQTEKNKQDSTAKEAEVR 95 >1ZU2-A nrPDB Length = 158 Score = 28.2 bits (61), Expect = 7.9, Method: Composition-based stats. Identities = 19/84 (22%), Positives = 31/84 (36%), Gaps = 4/84 (4%) Query: 157 QKAKAAFEKALEVEPDNPE----FNIGYAITVYRLDDSDREGSVKSFSLGPLRKAVTLNP 212 Q+A FE+AL ++P E Y + D + ++AV P Sbjct: 63 QEAITKFEEALLIDPKKDEAVWCIGNAYTSFAFLTPDETEAKHNFDLATQFFQQAVDEQP 122 Query: 213 DNSYIKVFLALKLQDVHAEAEGEK 236 DN++ L + + AE K Sbjct: 123 DNTHYLKSLEMTAKAPQLHAEAYK 146 >4I1A-A nrPDB Length = 391 Score = 28.2 bits (61), Expect = 8.1, Method: Composition-based stats. Identities = 18/113 (15%), Positives = 41/113 (36%), Gaps = 11/113 (9%) Query: 101 AWVYYHMDQLEEAQKYTGKIGNVCKKLSSPSNYKLECPETDCEKGWALLKFGGKYYQKAK 160 ++VYY+M Q + Y + + ++ + + C L+ Y++A Sbjct: 150 SYVYYYMKQTYFSMNYANRALKIFREYEEYAVQTVRCQFIVAGNLIDSLE-----YERAL 204 Query: 161 AAFEKALEVEPDN------PEFNIGYAITVYRLDDSDREGSVKSFSLGPLRKA 207 F K+LE+ ++ ++ I L + + +L K+ Sbjct: 205 EQFLKSLEISKESNIEHLIAMSHMNIGICYDELKEYKKASQHLILALEIFEKS 257 >4GYO-A nrPDB Length = 373 Score = 28.2 bits (61), Expect = 8.1, Method: Composition-based stats. Identities = 49/230 (21%), Positives = 79/230 (34%), Gaps = 39/230 (16%) Query: 262 KNSWNKALELLKKALEVTPTSSFLHHQMGLCYRAQMIQIKKATHNRPKGKDKLKVDELI- 320 ++ KA E L K EV + Y +Q + I T G+ +++ + +I Sbjct: 133 EDEIEKA-EFLFKVAEVY--YHIKQTYFSMNYASQALDI--YTKYELYGRRRVQCEFIIA 187 Query: 321 ---------SSAIFHFKAAMERDSMFAFAYTDLANMYAEG------GQYSNAEDIFRKAL 365 A+ H +A+E AY A Y G G Y AE F+ A Sbjct: 188 GNLTDVYHHEKALTHLCSALEHARQLEEAYMIAAAYYNVGHCKYSLGDYKEAEGYFKTA- 246 Query: 366 RLENITDDHKHQIHYHYGRFQEFHRKSE----NTAIHHYLEALKV-----KDRSPLRTKL 416 I ++H Q F H + + A+ Y +K D + +L Sbjct: 247 --AAIFEEHNFQQAVQAV-FSLTHIYCKEGKYDKAVEAYDRGIKSAAEWEDDMYLTKFRL 303 Query: 417 TSAL----KKLSTKRLCHNALDV-QSLSALGFVYKLEGEKRQAAEYYEKA 461 L L+ C + L+ Q L+ + E+ E+YE A Sbjct: 304 IHELYLGSGDLNVLTECFDLLESRQLLADAEDLLHDTAERFNQLEHYESA 353 >5ZYQ-A nrPDB Length = 320 Score = 28.2 bits (61), Expect = 8.1, Method: Composition-based stats. Identities = 15/63 (23%), Positives = 22/63 (34%), Gaps = 7/63 (11%) Query: 153 GKYYQKAKAAFEKALEVEPDNPEFNIGYAITVYRLDDSDREGSVKSFSLGPLRKAVTLNP 212 G +A A F L P+N +G A + D +L +KA+ NP Sbjct: 142 GDKMDQADAQFHFVLNQSPNNIPALLGKACISFNKKDYRG-------ALAYYKKALRTNP 194 Query: 213 DNS 215 Sbjct: 195 GCP 197 >5BUO-A nrPDB Length = 342 Score = 28.2 bits (61), Expect = 8.3, Method: Composition-based stats. Identities = 34/179 (18%), Positives = 70/179 (39%), Gaps = 19/179 (10%) Query: 293 YRAQMIQIK-KATHNRPKGKDKLKVDELISSAIFHFKAAME------RDSMFAFAYTDLA 345 +R +M Q+ + + K+ K D+ + I HF+ +E + T +A Sbjct: 34 HRERMSQVMREWEEAERQAKNLPKADK--KAVIQHFQEKVESLEQEAANERQQLVETHMA 91 Query: 346 NMYA-EGGQYSNAEDIFRKALRLENITDDHKHQIHYHYGRFQEFHRKSENTAIHHYLEAL 404 + A + A + + AL+ H + Y R ++ R+ H + + Sbjct: 92 RVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEH-VRMV 150 Query: 405 KVKDRSPLRTKLTSALKKLSTKRLCHNALDVQSLSALGFVYKLEGEKR-QAAEYYEKAQ 462 K + +R+++ + L+ + + QSLS L V + E + + E +K Q Sbjct: 151 DPKKAAQIRSQVMTHLRVIYERM-------NQSLSLLYNVPAVAEEIQDEVDELLQKEQ 202 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.313 0.127 0.324 Lambda K H 0.267 0.0391 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 16,831,858 Number of Sequences: 36641 Number of extensions: 625806 Number of successful extensions: 2447 Number of sequences better than 10.0: 84 Number of HSP's better than 10.0 without gapping: 57 Number of HSP's successfully gapped in prelim test: 75 Number of HSP's that attempted gapping in prelim test: 2081 Number of HSP's gapped (non-prelim): 308 length of query: 482 length of database: 10,336,785 effective HSP length: 101 effective length of query: 381 effective length of database: 6,636,044 effective search space: 2528332764 effective search space used: 2528332764 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.5 bits) S2: 61 (28.2 bits)