BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q13231 (466 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 1WB0-A nrPDB 927 0.0 4WKA-A nrPDB 759 0.0 3RM8-A nrPDB 461 e-130 4P8U-A nrPDB 404 e-113 1HJW-A nrPDB 404 e-113 5XEP-A nrPDB 395 e-110 5WUS-A nrPDB 391 e-109 5WV8-A nrPDB 389 e-108 2QF8-A nrPDB 387 e-108 1E9L-A nrPDB 376 e-105 6G9C-A nrPDB 370 e-103 5Y29-A nrPDB 303 1e-82 3W4R-A nrPDB 292 2e-79 3WKZ-A nrPDB 285 3e-77 5Y2C-A nrPDB 273 9e-74 1ITX-A nrPDB 205 3e-53 4MNK-A nrPDB 205 4e-53 6BT9-A nrPDB 201 4e-52 3AQU-A nrPDB 199 2e-51 5GZU-A nrPDB 180 1e-45 6EPB-A nrPDB 171 5e-43 3G6L-A nrPDB 170 1e-42 3ALF-A nrPDB 170 1e-42 1LL6-A nrPDB 161 7e-40 4URI-A nrPDB 160 1e-39 3CHF-A nrPDB 156 2e-38 1JNE-A nrPDB 152 3e-37 3WD0-A nrPDB 146 2e-35 5ZL9-A nrPDB 127 9e-30 5XWF-A nrPDB 127 1e-29 1KFW-A nrPDB 125 3e-29 4TXG-A nrPDB 120 1e-27 3ARQ-A nrPDB 119 3e-27 5GQB-A nrPDB 115 4e-26 3QOK-A nrPDB 114 1e-25 5Z7M-A nrPDB 112 4e-25 6F8N-A nrPDB 112 4e-25 5DF0-A nrPDB 103 1e-22 4W5U-B nrPDB 89 6e-18 4DWS-C nrPDB 87 2e-17 6OGD-C nrPDB 87 2e-17 4A5Q-A nrPDB 81 1e-15 4Q6T-A nrPDB 59 4e-09 4WIW-A nrPDB 56 4e-08 3CZ8-A nrPDB 42 4e-04 4S3K-A nrPDB 38 0.008 3N18-A nrPDB 38 0.009 5JH8-A nrPDB 37 0.014 3CO4-A nrPDB 37 0.014 3SIM-A nrPDB 37 0.015 3IAN-A nrPDB 37 0.021 3EBV-A nrPDB 37 0.022 4TX8-A nrPDB 37 0.023 4Z4A-A nrPDB 36 0.041 4NUY-A nrPDB 36 0.044 2Y8V-A nrPDB 35 0.087 2QU8-A nrPDB 32 0.58 4RL3-A nrPDB 32 0.68 6BN0-A nrPDB 31 0.89 1FJ2-A nrPDB 31 0.94 5E1J-A nrPDB 31 1.1 3BXW-B nrPDB 31 1.1 1CR6-A nrPDB 31 1.2 4S3J-A nrPDB 30 2.8 3SM3-A nrPDB 29 3.4 1DQC-A nrPDB 28 7.7 4DDQ-A nrPDB 28 8.1 6FTI-5 nrPDB 28 9.5 >1WB0-A nrPDB Length = 445 Score = 927 bits (2396), Expect = 0.0, Method: Compositional matrix adjust. Identities = 445/445 (100%), Positives = 445/445 (100%) Query: 22 AKLVCYFTNWAQYRQGEARFLPKDLDPSLCTHLIYAFAGMTNHQLSTTEWNDETLYQEFN 81 AKLVCYFTNWAQYRQGEARFLPKDLDPSLCTHLIYAFAGMTNHQLSTTEWNDETLYQEFN Sbjct: 1 AKLVCYFTNWAQYRQGEARFLPKDLDPSLCTHLIYAFAGMTNHQLSTTEWNDETLYQEFN 60 Query: 82 GLKKMNPKLKTLLAIGGWNFGTQKFTDMVATANNRQTFVNSAIRFLRKYSFDGLDLDWEY 141 GLKKMNPKLKTLLAIGGWNFGTQKFTDMVATANNRQTFVNSAIRFLRKYSFDGLDLDWEY Sbjct: 61 GLKKMNPKLKTLLAIGGWNFGTQKFTDMVATANNRQTFVNSAIRFLRKYSFDGLDLDWEY 120 Query: 142 PGSQGSPAVDKERFTTLVQDLANAFQQEAQTSGKERLLLSAAVPAGQTYVDAGYEVDKIA 201 PGSQGSPAVDKERFTTLVQDLANAFQQEAQTSGKERLLLSAAVPAGQTYVDAGYEVDKIA Sbjct: 121 PGSQGSPAVDKERFTTLVQDLANAFQQEAQTSGKERLLLSAAVPAGQTYVDAGYEVDKIA 180 Query: 202 QNLDFVNLMAYDFHGSWEKVTGHNSPLYKRQEESGAAASLNVDAAVQQWLQKGTPASKLI 261 QNLDFVNLMAYDFHGSWEKVTGHNSPLYKRQEESGAAASLNVDAAVQQWLQKGTPASKLI Sbjct: 181 QNLDFVNLMAYDFHGSWEKVTGHNSPLYKRQEESGAAASLNVDAAVQQWLQKGTPASKLI 240 Query: 262 LGMPTYGRSFTLASSSDTRVGAPATGSGTPGPFTKEGGMLAYYEVCSWKGATKQRIQDQK 321 LGMPTYGRSFTLASSSDTRVGAPATGSGTPGPFTKEGGMLAYYEVCSWKGATKQRIQDQK Sbjct: 241 LGMPTYGRSFTLASSSDTRVGAPATGSGTPGPFTKEGGMLAYYEVCSWKGATKQRIQDQK 300 Query: 322 VPYIFRDNQWVGFDDVESFKTKVSYLKQKGLGGAMVWALDLDDFAGFSCNQGRYPLIQTL 381 VPYIFRDNQWVGFDDVESFKTKVSYLKQKGLGGAMVWALDLDDFAGFSCNQGRYPLIQTL Sbjct: 301 VPYIFRDNQWVGFDDVESFKTKVSYLKQKGLGGAMVWALDLDDFAGFSCNQGRYPLIQTL 360 Query: 382 RQELSLPYLPSGTPELEVPKPGQPSEPEHGPSPGQDTFCQGKADGLYPNPRERSSFYSCA 441 RQELSLPYLPSGTPELEVPKPGQPSEPEHGPSPGQDTFCQGKADGLYPNPRERSSFYSCA Sbjct: 361 RQELSLPYLPSGTPELEVPKPGQPSEPEHGPSPGQDTFCQGKADGLYPNPRERSSFYSCA 420 Query: 442 AGRLFQQSCPTGLVFSNSCKCCTWN 466 AGRLFQQSCPTGLVFSNSCKCCTWN Sbjct: 421 AGRLFQQSCPTGLVFSNSCKCCTWN 445 >4WKA-A nrPDB Length = 377 Score = 759 bits (1959), Expect = 0.0, Method: Compositional matrix adjust. Identities = 368/373 (98%), Positives = 370/373 (99%), Gaps = 2/373 (0%) Query: 22 AKLVCYFTNWAQYRQGEARFLPKDLDPSLCTHLIYAFAGMTNHQLSTTEWNDETLYQEFN 81 AKLVCYFTNWAQYRQGEARFLPKDLDPSLCTHLIYAFAGMTNHQLSTTEWNDETLYQEFN Sbjct: 1 AKLVCYFTNWAQYRQGEARFLPKDLDPSLCTHLIYAFAGMTNHQLSTTEWNDETLYQEFN 60 Query: 82 GLKKMNPKLKTLLAIGGWNFGTQKFTDMVATANNRQTFVNSAIRFLRKYSFDGLDLDWEY 141 GLKKMNPKLKTLLAIGGWNFGTQKFTDMVATANNRQTFVNSAIRFLRKYSFDGLDLDWEY Sbjct: 61 GLKKMNPKLKTLLAIGGWNFGTQKFTDMVATANNRQTFVNSAIRFLRKYSFDGLDLDWEY 120 Query: 142 PGSQGSPAVDKERFTTLVQDLANAFQQEAQTSGKERLLLSAAVPAGQTYVDAGYEVDKIA 201 PGSQGSPAVDKERFTTLVQDLANAFQQEAQTSGKERLLLSAAVPAGQTYVDAGYEVDKIA Sbjct: 121 PGSQGSPAVDKERFTTLVQDLANAFQQEAQTSGKERLLLSAAVPAGQTYVDAGYEVDKIA 180 Query: 202 QNLDFVNLMAYDFHGSWEKVTGHNSPLYKRQEESGAAASLNVDAAVQQWLQKGTPASKLI 261 QNLDFVNLMAYDFHGSWEKVTGHNSPLYKRQEESGAAASLNVDAAVQQWLQKGTPASKLI Sbjct: 181 QNLDFVNLMAYDFHGSWEKVTGHNSPLYKRQEESGAAASLNVDAAVQQWLQKGTPASKLI 240 Query: 262 LGMPTYGRSFTLASSSDTRVGAPATGSGTPGPFTKEGGMLAYYEVCSWKGATKQRIQDQK 321 LGMPTYGRSFTLASSSDTRVGAPATGSGTPGPFTKEGGMLAYYEVCSWKGATKQRIQDQK Sbjct: 241 LGMPTYGRSFTLASSSDTRVGAPATGSGTPGPFTKEGGMLAYYEVCSWKGATKQRIQDQK 300 Query: 322 VPYIFRDNQWVGFDDVESFKTKVSYLKQKGLGGAMVWALDLDDFAGFSCNQGRYPLIQTL 381 VPYIFRDNQWVGFDDVESFKTKVSYLKQKGLGGAMVWALDLDDFAGFSCNQGRYPLIQTL Sbjct: 301 VPYIFRDNQWVGFDDVESFKTKVSYLKQKGLGGAMVWALDLDDFAGFSCNQGRYPLIQTL 360 Query: 382 RQELSLPYLPSGT 394 RQELSL +P G+ Sbjct: 361 RQELSL--VPRGS 371 >3RM8-A nrPDB Length = 395 Score = 461 bits (1186), Expect = e-130, Method: Compositional matrix adjust. Identities = 216/388 (55%), Positives = 278/388 (71%), Gaps = 9/388 (2%) Query: 23 KLVCYFTNWAQYRQGEARFLPKDLDPSLCTHLIYAFAGMTNHQLSTTEWNDETLYQEFNG 82 +L CYFTNWAQYR G RF+P D++P LCTHLIYAFAGM N++++T EWND TLYQ FNG Sbjct: 2 QLTCYFTNWAQYRPGLGRFMPDDINPCLCTHLIYAFAGMQNNEITTIEWNDVTLYQAFNG 61 Query: 83 LKKMNPKLKTLLAIGGWNFGTQKFTDMVATANNRQTFVNSAIRFLRKYSFDGLDLDWEYP 142 LK N +LKTLLAIGGWNFGT FT MV+T NRQTF+ S I+FLR+Y FDGLD DWEYP Sbjct: 62 LKNKNSQLKTLLAIGGWNFGTAPFTAMVSTPENRQTFITSVIKFLRQYEFDGLDFDWEYP 121 Query: 143 GSQGSPAVDKERFTTLVQDLANAFQQEAQTSGKERLLLSAAVPAGQTYVDAGYEVDKIAQ 202 GS+GSP DK FT LVQ++ AF+QEA+ K RL+++AAV AG + + +GYE+ +++Q Sbjct: 122 GSRGSPPQDKHLFTVLVQEMREAFEQEAKQINKPRLMVTAAVAAGISNIQSGYEIPQLSQ 181 Query: 203 NLDFVNLMAYDFHGSWEKVTGHNSPLYKRQEESGAAASLNVDAAVQQWLQKGTPASKLIL 262 LD++++M YD HGSWE TG NSPLYK ++G+ A LNVD + W G PA KLI+ Sbjct: 182 YLDYIHVMTYDLHGSWEGYTGENSPLYKYPTDTGSNAYLNVDYVMNYWKDNGAPAEKLIV 241 Query: 263 GMPTYGRSFTLASSSDTRVGAPATGSGTPGPFTKEGGMLAYYEVCSW--KGATKQRIQDQ 320 G PTYG +F L++ S+T +GAP +G+G GP+ KE G+ AYYE+C++ GAT+ Q Sbjct: 242 GFPTYGHNFILSNPSNTGIGAPTSGAGPAGPYAKESGIWAYYEICTFLKNGATQGWDAPQ 301 Query: 321 KVPYIFRDNQWVGFDDVESFKTKVSYLKQKGLGGAMVWALDLDDFAGFSCNQGRYPLIQT 380 +VPY ++ N WVG+D+V+SF K +LK GGAMVWA+DLDDF G CNQG++PLI T Sbjct: 302 EVPYAYQGNVWVGYDNVKSFDIKAQWLKHNKFGGAMVWAIDLDDFTGTFCNQGKFPLIST 361 Query: 381 LRQELSLPYLPSGTPELEVPKPGQPSEP 408 L++ L G P QP EP Sbjct: 362 LKKAL-------GLQSASCTAPAQPIEP 382 >4P8U-A nrPDB Length = 371 Score = 404 bits (1039), Expect = e-113, Method: Compositional matrix adjust. Identities = 189/366 (51%), Positives = 265/366 (72%), Gaps = 9/366 (2%) Query: 23 KLVCYFTNWAQYRQGEARFLPKDLDPSLCTHLIYAFAGMTNHQLSTTEWNDETLYQEFNG 82 KLVCYFTNW+Q RQ +F P+++DP LC+HLIY+FA + N+++ + ++ LYQ N Sbjct: 9 KLVCYFTNWSQDRQEPGKFTPENIDPFLCSHLIYSFASIENNKVIIKDKSEVMLYQTINS 68 Query: 83 LKKMNPKLKTLLAIGGWNFGTQKFTDMVATANNRQTFVNSAIRFLRKYSFDGLDLDWEYP 142 LK NPKLK LL+IGG+ FG++ F MV ++ +R F+NS I FLR ++FDGLD+ W YP Sbjct: 69 LKTKNPKLKILLSIGGYLFGSKGFHPMVDSSTSRLEFINSIILFLRNHNFDGLDVSWIYP 128 Query: 143 GSQGSPAVDKERFTTLVQDLANAFQQEAQTSGKERLLLSAAVPAGQTYVDAGYEVDKIAQ 202 + + FT L+ +LA AFQ++ S KERLLL+ V AG+ +D Y+V+K+A+ Sbjct: 129 DQK-----ENTHFTVLIHELAEAFQKDFTKSTKERLLLTVGVSAGRQMIDNSYQVEKLAK 183 Query: 203 NLDFVNLMAYDFHGSWEK--VTGHNSPLYKRQEESGAAASLNVDAAVQQWLQKGTPASKL 260 +LDF+NL+++DFHGSWEK +TGHNSPL K ++ G ++ NV+ AV W+ KG P+ K+ Sbjct: 184 DLDFINLLSFDFHGSWEKPLITGHNSPLSKGWQDRGPSSYYNVEYAVGYWIHKGMPSEKV 243 Query: 261 ILGMPTYGRSFTLASSSDTRVGAPATGSGTPGPFTKEGGMLAYYEVCSW-KGATKQRIQD 319 ++G+PTYG SFTLA S++T VGAPA+G G GP T+ G LAYYE+C + KGA +QD Sbjct: 244 VMGIPTYGHSFTLA-SAETTVGAPASGPGAAGPITESSGFLAYYEICQFLKGAKITWLQD 302 Query: 320 QKVPYIFRDNQWVGFDDVESFKTKVSYLKQKGLGGAMVWALDLDDFAGFSCNQGRYPLIQ 379 Q+VPY + NQWVG+DDV+S +TKV +LK LGGAM+W++D+DDF G SCNQG YPL+Q Sbjct: 303 QQVPYAVKGNQWVGYDDVKSMETKVQFLKNLNLGGAMIWSIDMDDFTGKSCNQGPYPLVQ 362 Query: 380 TLRQEL 385 +++ L Sbjct: 363 AVKRSL 368 >1HJW-A nrPDB Length = 362 Score = 404 bits (1038), Expect = e-113, Method: Compositional matrix adjust. Identities = 196/366 (53%), Positives = 262/366 (71%), Gaps = 9/366 (2%) Query: 23 KLVCYFTNWAQYRQGEARFLPKDLDPSLCTHLIYAFAGMTNHQLSTTEWNDETLYQEFNG 82 KLVCY+T+W+QYR+G+ P LD LCTH+IY+FA ++N + T EWND TLY N Sbjct: 2 KLVCYYTSWSQYREGDGSCFPDALDRFLCTHIIYSFANISNDHIDTWEWNDVTLYGMLNT 61 Query: 83 LKKMNPKLKTLLAIGGWNFGTQKFTDMVATANNRQTFVNSAIRFLRKYSFDGLDLDWEYP 142 LK NP LKTLL++GGWNFG+Q+F+ + + +R+TF+ S FLR + FDGLDL W YP Sbjct: 62 LKNRNPNLKTLLSVGGWNFGSQRFSKIASNTQSRRTFIKSVPPFLRTHGFDGLDLAWLYP 121 Query: 143 GSQGSPAVDKERFTTLVQDLANAFQQEAQTSGKERLLLSAAVPAGQTYVDAGYEVDKIAQ 202 G + DK+ FTTL++++ F +EAQ GK++LLLSAA+ AG+ +D+ Y++ KI+Q Sbjct: 122 GRR-----DKQHFTTLIKEMKAEFIKEAQ-PGKKQLLLSAALSAGKVTIDSSYDIAKISQ 175 Query: 203 NLDFVNLMAYDFHGSWEKVTGHNSPLYKRQEESGAAASLNVDAAVQQWLQKGTPASKLIL 262 +LDF+++M YDFHG+W TGH+SPL++ QE++ N D AV L+ G PASKL++ Sbjct: 176 HLDFISIMTYDFHGAWRGTTGHHSPLFRGQEDASPDRFSNTDYAVGYMLRLGAPASKLVM 235 Query: 263 GMPTYGRSFTLASSSDTRVGAPATGSGTPGPFTKEGGMLAYYEVCSW-KGATKQRIQDQK 321 G+PT+GRSFTLA SS+T VGAP +G G PG FTKE G LAYYE+C + +GAT RI Q+ Sbjct: 236 GIPTFGRSFTLA-SSETGVGAPISGPGIPGRFTKEAGTLAYYEICDFLRGATVHRILGQQ 294 Query: 322 VPYIFRDNQWVGFDDVESFKTKVSYLKQKGLGGAMVWALDLDDFAGFSCNQG-RYPLIQT 380 VPY + NQWVG+DD ES K+KV YLK + L GAMVWALDLDDF G C Q R+PL Sbjct: 295 VPYATKGNQWVGYDDQESVKSKVQYLKDRQLAGAMVWALDLDDFQGSFCGQDLRFPLTNA 354 Query: 381 LRQELS 386 ++ L+ Sbjct: 355 IKDALA 360 >5XEP-A nrPDB Length = 381 Score = 395 bits (1015), Expect = e-110, Method: Compositional matrix adjust. Identities = 194/388 (50%), Positives = 270/388 (69%), Gaps = 9/388 (2%) Query: 1 MVRSVAWAGFMVLLMIPWGSAAKLVCYFTNWAQYRQGEARFLPKDLDPSLCTHLIYAFAG 60 M A GF VL+++ SA KLVCYFT+W+QYR+G FLP + P LCTH+IY+FA Sbjct: 1 MGMRAALTGFAVLMLLQSCSAYKLVCYFTSWSQYREGVGSFLPDAIQPFLCTHIIYSFAN 60 Query: 61 MT-NHQLSTTEWNDETLYQEFNGLKKMNPKLKTLLAIGGWNFGTQKFTDMVATANNRQTF 119 ++ ++ LST EWNDE+ Y + N LK N LKTLL++GGW FG ++F+++ + R F Sbjct: 61 ISSDNMLSTWEWNDESNYDKLNKLKTRNTNLKTLLSVGGWKFGGKRFSEIASNTERRTAF 120 Query: 120 VNSAIRFLRKYSFDGLDLDWEYPGSQGSPAVDKERFTTLVQDLANAFQQEAQTSGKERLL 179 V S FLR Y FDGLDL W YP + DK+ F+TL+++L F +E Q G+E+LL Sbjct: 121 VRSVAPFLRSYGFDGLDLAWLYPRLR-----DKQYFSTLIKELNAEFTKEVQ-PGREKLL 174 Query: 180 LSAAVPAGQTYVDAGYEVDKIAQNLDFVNLMAYDFHGSWEKVTGHNSPLYKRQEESGAAA 239 LSAA+ AG+ +D GY++ +IAQ+LDF+NLM YDFHG W ++TGH+SPL++ Q+++ Sbjct: 175 LSAALSAGKVAIDTGYDIAQIAQHLDFINLMTYDFHGVWRQITGHHSPLFQGQKDTRFDR 234 Query: 240 SLNVDAAVQQWLQKGTPASKLILGMPTYGRSFTLASSSDTRVGAPATGSGTPGPFTKEGG 299 NV+ AVQ ++ G ASKL++G+PT+G+SFTLA SS+ ++GAP +G G PG FTKE G Sbjct: 235 YSNVNYAVQYMIRLGAQASKLLMGIPTFGKSFTLA-SSENQLGAPISGEGLPGRFTKEAG 293 Query: 300 MLAYYEVCSW-KGATKQRIQDQKVPYIFRDNQWVGFDDVESFKTKVSYLKQKGLGGAMVW 358 LAYYE+C + KGA R+ ++KVP+ + NQWVG++D ES K KV +LK+K L GAMVW Sbjct: 294 TLAYYEICDFLKGAEVHRLSNEKVPFATKGNQWVGYEDKESVKNKVRFLKEKKLAGAMVW 353 Query: 359 ALDLDDFAGFSCNQGRYPLIQTLRQELS 386 ALDLDDF G + +PL ++ L+ Sbjct: 354 ALDLDDFQGTCQPKEFFPLTNAIKDALA 381 >5WUS-A nrPDB Length = 460 Score = 391 bits (1005), Expect = e-109, Method: Compositional matrix adjust. Identities = 190/451 (42%), Positives = 283/451 (62%), Gaps = 19/451 (4%) Query: 23 KLVCYFTNWAQYRQGEARFLPKDLDPSLCTHLIYAFAGMTNHQLSTTEWNDETLYQEFNG 82 +++CY T+W+ R RF+P+++DP+LCTH+IYAFA + +H+L+ + D +Y + Sbjct: 3 QVLCYLTSWSSKRPSAGRFMPENVDPTLCTHVIYAFATLKDHKLTEADEKDADMYDKVVA 62 Query: 83 LKKMNPKLKTLLAIGGWNFGTQKFTDMVATANNRQTFVNSAIRFLRKYSFDGLDLDWEYP 142 L++ NP LK LLAIGGW FG+ F ++ + FV AI FLR Y F+GLD+DWEYP Sbjct: 63 LREKNPNLKILLAIGGWAFGSTPFKELTSNVFRMNQFVYEAIEFLRDYQFNGLDVDWEYP 122 Query: 143 GSQGSPAVDKERFTTLVQDLANAFQQEAQTSGKERLLLSAAVPAGQTYVDAGYEVDKIAQ 202 A D+ F +L+++L AF+ EA+TSG+ RLLL+AAVPA + AGY+V +I++ Sbjct: 123 RG----ADDRAAFVSLLKELRLAFEGEAKTSGQPRLLLTAAVPASFEAIAAGYDVPEISK 178 Query: 203 NLDFVNLMAYDFHGSWEKVTGHNSPLYKRQEESGAAASLNVDAAVQQWLQKGTPASKLIL 262 LDF+N+M YDFHG WE+ GHNSPL+ + + L VD + ++W+++G P KL++ Sbjct: 179 YLDFINVMTYDFHGQWERQVGHNSPLFPLESATSYQKKLTVDYSAREWVRQGAPKEKLMI 238 Query: 263 GMPTYGRSFTLASSSDTRVGAPATGSGTPGPFTKEGGMLAYYEVCSWKGATKQRI---QD 319 GMPTYGRSFTL + + +GAPA+G G G FT E G ++YYE+C + + + Sbjct: 239 GMPTYGRSFTLINDTQFDIGAPASGGGQAGRFTNEAGFMSYYEICEFLREDNTTLVWDNE 298 Query: 320 QKVPYIFRDNQWVGFDDVESFKTKVSYLKQKGLGGAMVWALDLDDFAGFSCNQGRYPLIQ 379 Q VP+ +R++QWVGFDD S KTK+++LK++G GG MVW++D+DDF G SC G+YPLI Sbjct: 299 QMVPFAYREDQWVGFDDERSLKTKMAWLKEEGFGGIMVWSVDMDDFRG-SCGTGKYPLIT 357 Query: 380 TLRQELSLPYLPSGTPELEVPKPGQPSEP--EHGPSPGQDTFCQGKADGLYPNPRERSS- 436 ++QELS +LE P + S P ++ + C+ + DG ++ + Sbjct: 358 AMKQELS-----GYKVKLEYDGPYESSSPTGQYTTKDPHEVTCE-EEDGHISYHKDHADC 411 Query: 437 --FYSCAAGRLFQQSCPTGLVFSNSCKCCTW 465 +Y C R CP+ LVF+ + C W Sbjct: 412 TMYYMCEGERKHHMPCPSNLVFNPNENVCDW 442 >5WV8-A nrPDB Length = 482 Score = 389 bits (998), Expect = e-108, Method: Compositional matrix adjust. Identities = 190/372 (51%), Positives = 249/372 (66%), Gaps = 13/372 (3%) Query: 23 KLVCYFTNWAQYRQGEARFLPKDLDPSLCTHLIYAFAGMTNHQLSTTEWNDET------L 76 K+VCY+TNW+QYR +F+P+D+ P LCTH+I+AF + +LS+ E NDET L Sbjct: 94 KIVCYYTNWSQYRTKIGKFMPEDIQPELCTHIIFAFGWLKKGKLSSFESNDETKDGKTGL 153 Query: 77 YQEFNGLKKMNPKLKTLLAIGGWNFGTQKFTDMVATANNRQTFVNSAIRFLRKYSFDGLD 136 Y N LKK NPKLKTLLAIGGW+FGTQKF +M AT RQTF+ SAI +LR +FDGLD Sbjct: 154 YDRINALKKANPKLKTLLAIGGWSFGTQKFKEMSATRYARQTFIYSAIPYLRDRNFDGLD 213 Query: 137 LDWEYPGSQGSPAVDKERFTTLVQDLANAFQQEAQTSGKERLLLSAAVPAGQTYVDAGYE 196 +DW YP DK+ + L+++L AF+ EAQ K RLLL+AAVP G + +GY+ Sbjct: 214 IDWLYPKG----GDDKKNYVLLLKELREAFEAEAQEVKKPRLLLTAAVPVGPDNIKSGYD 269 Query: 197 VDKIAQNLDFVNLMAYDFHGSWEKVTGHNSPLYKRQEESGAAASLNVDAAVQQWLQKGTP 256 V +A LDF+NLMAYDFHG WE+ TGHN+PLY +S L+VD A W++ G P Sbjct: 270 VPAVASYLDFINLMAYDFHGKWERETGHNAPLYAPSSDSEWRKQLSVDHAAHLWVKLGAP 329 Query: 257 ASKLILGMPTYGRSFTLASSSDTRVGAPATGSGTPGPFTKEGGMLAYYEVCSW--KGATK 314 KLI+GMPTYGR+FTL++ ++ +V +PA+G G G +TKE G LAYYEVC G Sbjct: 330 KEKLIIGMPTYGRTFTLSNPNNFKVNSPASGGGKAGEYTKESGFLAYYEVCEILRNGGAY 389 Query: 315 QRIQDQKVPYIFRDNQWVGFDDVESFKTKVSYLKQKGLGGAMVWALDLDDFAGFSCNQG- 373 + KVPY +QWVGFDD +S + K+ ++K GGAMVW +D+DDF+G C Sbjct: 390 VWDDEMKVPYAIHGDQWVGFDDEKSIRNKMRWIKDNSFGGAMVWTVDMDDFSGGVCGGNV 449 Query: 374 RYPLIQTLRQEL 385 +YPLI +R+EL Sbjct: 450 KYPLIGAMREEL 461 >2QF8-A nrPDB Length = 361 Score = 387 bits (994), Expect = e-108, Method: Compositional matrix adjust. Identities = 186/366 (50%), Positives = 259/366 (70%), Gaps = 10/366 (2%) Query: 23 KLVCYFTNWAQYRQGEARFLPKDLDPSLCTHLIYAFAGMTNHQLSTTEWNDETLYQEFNG 82 KL+CY+T+W+QYR+G+ P +DP LCTH+IY+FA ++N+++ T EWND TLY N Sbjct: 2 KLICYYTSWSQYREGDGSCFPDAIDPFLCTHVIYSFANISNNEIDTWEWNDVTLYDTLNT 61 Query: 83 LKKMNPKLKTLLAIGGWNFGTQKFTDMVATANNRQTFVNSAIRFLRKYSFDGLDLDWEYP 142 LK NP LKTLL++GGWN+G+Q+F+ + + +R+TF+ S FLR + FDGLDL W +P Sbjct: 62 LKNRNPNLKTLLSVGGWNYGSQRFSKIASKTQSRRTFIKSVPPFLRTHGFDGLDLAWLWP 121 Query: 143 GSQGSPAVDKERFTTLVQDLANAFQQEAQTSGKERLLLSAAVPAGQTYVDAGYEVDKIAQ 202 G + DK TTLV+++ F +EAQ +G E+LLLSAAV AG+ +D GY++ +I++ Sbjct: 122 GWR-----DKRHLTTLVKEMKAEFVREAQ-AGTEQLLLSAAVTAGKIAIDRGYDIAQISR 175 Query: 203 NLDFVNLMAYDFHGSWEKVTGHNSPLYKRQEESGAAASLNVDAAVQQWLQKGTPASKLIL 262 +LDF++L+ YDFHG+W + GH+SPL++ E++ + S N D AV L+ G PA+KL++ Sbjct: 176 HLDFISLLTYDFHGAWRQTVGHHSPLFRGNEDASSRFS-NADYAVSYMLRLGAPANKLVM 234 Query: 263 GMPTYGRSFTLASSSDTRVGAPATGSGTPGPFTKEGGMLAYYEVCSW-KGATKQRIQDQK 321 G+PT+GRS+TLASS T VGAP +G G PG FTK G+LAYYE+C + GAT R +DQ+ Sbjct: 235 GIPTFGRSYTLASSK-TDVGAPISGPGIPGRFTKWKGILAYYEICDFLHGATTHRFRDQQ 293 Query: 322 VPYIFRDNQWVGFDDVESFKTKVSYLKQKGLGGAMVWALDLDDFAGFSCNQG-RYPLIQT 380 VPY + NQWV +DD ES K K YLK + L GAMVWALDLDDF G C Q +PL Sbjct: 294 VPYATKGNQWVAYDDQESVKNKARYLKNRQLAGAMVWALDLDDFRGTFCGQNLTFPLTSA 353 Query: 381 LRQELS 386 ++ L+ Sbjct: 354 IKDVLA 359 >1E9L-A nrPDB Length = 377 Score = 376 bits (966), Expect = e-105, Method: Compositional matrix adjust. Identities = 176/367 (47%), Positives = 250/367 (68%), Gaps = 2/367 (0%) Query: 23 KLVCYFTNWAQYRQGEARFLPKDLDPSLCTHLIYAFAGMTNHQLSTTEWNDETLYQEFNG 82 +L+CY+T+WA+ R E F P ++DP LCTHLIYAFAGM N++++ T D Y+ NG Sbjct: 2 QLMCYYTSWAKDRPIEGSFKPGNIDPCLCTHLIYAFAGMQNNEITYTHEQDLRDYEALNG 61 Query: 83 LKKMNPKLKTLLAIGGWNFGTQKFTDMVATANNRQTFVNSAIRFLRKYSFDGLDLDWEYP 142 LK N +LKTLLAIGGW FG F+ MV+T NRQ F+ S IRFLR+Y+FDGL+LDW+YP Sbjct: 62 LKDKNTELKTLLAIGGWKFGPAPFSAMVSTPQNRQIFIQSVIRFLRQYNFDGLNLDWQYP 121 Query: 143 GSQGSPAVDKERFTTLVQDLANAFQQEAQTSGKERLLLSAAVPAGQTYVDAGYEVDKIAQ 202 GS+GSP DK F+ LV+++ AF++E+ RLLL++ + +GY++ +++Q Sbjct: 122 GSRGSPPKDKHLFSVLVKEMRKAFEEESVEKDIPRLLLTSTGAGIIDVIKSGYKIPELSQ 181 Query: 203 NLDFVNLMAYDFHGSWEKVTGHNSPLYKRQEESGAAASLNVDAAVQQWLQKGTPASKLIL 262 +LD++ +M YD H + TG NSPLYK + G +A LNVD+ + W G + KLI+ Sbjct: 182 SLDYIQVMTYDLHDPKDGYTGENSPLYKSPYDIGKSADLNVDSIISYWKDHGAASEKLIV 241 Query: 263 GMPTYGRSFTLASSSDTRVGAPATGSGTPGPFTKEGGMLAYYEVCSW--KGATKQRIQDQ 320 G P YG +F L+ S T +GAP +G PG +T E G+LAYYEVC++ +GAT+ Q Sbjct: 242 GFPAYGHTFILSDPSKTGIGAPTISTGPPGKYTDESGLLAYYEVCTFLNEGATEVWDAPQ 301 Query: 321 KVPYIFRDNQWVGFDDVESFKTKVSYLKQKGLGGAMVWALDLDDFAGFSCNQGRYPLIQT 380 +VPY ++ N+WVG+D+V SFK K +LK LGGA+VW LD+DDF+G C+Q +PL T Sbjct: 302 EVPYAYQGNEWVGYDNVRSFKLKAQWLKDNNLGGAVVWPLDMDDFSGSFCHQRHFPLTST 361 Query: 381 LRQELSL 387 L+ +L++ Sbjct: 362 LKGDLNI 368 >6G9C-A nrPDB Length = 495 Score = 370 bits (951), Expect = e-103, Method: Compositional matrix adjust. Identities = 194/447 (43%), Positives = 267/447 (59%), Gaps = 14/447 (3%) Query: 26 CYFTNWAQYRQGEARFLPKDLDPSLCTHLIYAFAGMTNH-QLSTTEWND-ETLYQEFNGL 83 CYFTNWAQYR G ++ P+ +LC ++ YAFA + + + EWND + LY Sbjct: 37 CYFTNWAQYRPGNGKYNPEHYQANLCEYIFYAFAKLNDDFTVDQFEWNDIDVLYPGVMKQ 96 Query: 84 KKMNPKLKTLLAIGGWNFGTQKFTDMVATANNRQTFVNSAIRFLRKYSFDGLDLDWEYPG 143 K P LK LL++GGWN GT F M AT +NR F++S + FL++ FDG DLDWEYP Sbjct: 97 KSSQPDLKVLLSLGGWNAGTATFKKMAATYSNRAKFISSLVSFLQQNKFDGFDLDWEYPE 156 Query: 144 SQGSPAVDKERFTTLVQDLANAFQQEAQTSGKERLLLSAAVPAGQTYVDAGYEVDKIAQN 203 S DKE + L Q++ F++ A+ + RLL +AAV A VDAGY+V +A+ Sbjct: 157 SS-----DKENYLLLCQEILAKFEEVAKCTSTSRLLFTAAVSANPKTVDAGYDVPALAKV 211 Query: 204 LDFVNLMAYDFHGSWEKVTGHNSPLYKRQEESGAAASLNVDAAVQQWLQKGTPASKLILG 263 LDFVNLM YDFHG+WE TG NSPLY R+E+S NV+ + + W KG P ++I+G Sbjct: 212 LDFVNLMCYDFHGAWETQTGINSPLYSRKEDSSEFKMWNVEQSSKYWSDKGMPKKQIIIG 271 Query: 264 MPTYGRSFTLASSSDTRVGAPATGSGTPGPFTKEGGMLAYYEVCSWKGATKQRIQDQ--K 321 +PTYGR +TL+ +S T +GAPA GS T + +E G+++YYEVC + +R+ D K Sbjct: 272 LPTYGRGWTLSDASKTDIGAPAQGSSTATEYLREAGVISYYEVCQKLSSGAKRVWDDESK 331 Query: 322 VPYIFRDNQWVGFDDVESFKTKVSYLKQKGLGGAMVWALDLDDFAGFSC---NQGRYPLI 378 PY+ + NQW +DDVES K K++++KQ+ GGA VW LD DDF G C N +YPLI Sbjct: 332 TPYLVQGNQWFSYDDVESMKAKINWIKQENYGGAFVWTLDYDDFLGSFCTEHNGKKYPLI 391 Query: 379 QTLRQELSLPYLPSGTPELEVPKPGQPSEPEHGPSPGQDTFCQGKADGLYPNPRERSSFY 438 +++ L Y+P T PS SP C +DGL+P+P S+FY Sbjct: 392 SLMQEILGGGYVPPSTESTTSQVTTTPSTTTSTTSPAGAFQC--PSDGLFPDPESCSNFY 449 Query: 439 SCAAGRLFQQSCPTGLVFSNSCKCCTW 465 CA G ++ CPTGL+F+ C + Sbjct: 450 QCAGGTAYKMKCPTGLMFNPKTSTCDY 476 >5Y29-A nrPDB Length = 377 Score = 303 bits (776), Expect = 1e-82, Method: Compositional matrix adjust. Identities = 162/384 (42%), Positives = 229/384 (59%), Gaps = 28/384 (7%) Query: 20 SAAKLVCYFTNWAQYRQGEARFLPKDLDPSLCTHLIYAFAGMTNHQLSTTE--WND--ET 75 S KLVCY+TNW+ YR G ++ P+D+DPSLCTH++Y FA + N L T W+D Sbjct: 5 SRYKLVCYYTNWSWYRPGIGKYSPEDIDPSLCTHIVYGFAVLGNDGLMTAHDTWSDYDNR 64 Query: 76 LYQEFNGLKKMNPKLKTLLAIGGWNFGT-QKFTDMVATANNRQTFVNSAIRFLRKYSFDG 134 Y+ K+ +K LA+GGWN K++ +V R FV A+ FL KY FDG Sbjct: 65 FYERVVEYKRYG--IKVSLALGGWNDSAGDKYSKLVNDPAARAKFVQHAVAFLEKYGFDG 122 Query: 135 LDLDWEYPG------SQGSPAVDKERFTTLVQDLANAFQQEAQTSGKERLLLSAAVPAGQ 188 LDLDWEYP S+G P DK+ F LV +L+ + + LLLSAAV + Sbjct: 123 LDLDWEYPKCWQVDCSKG-PDSDKQGFADLVHELSAVLKPKG-------LLLSAAVSPNK 174 Query: 189 TYVDAGYEVDKIAQNLDFVNLMAYDFHGSWEKVTGHNSPLYKRQEESGAAASLNVDAAVQ 248 +DAGY+V +A+ LD++ +M YD+HG W+K TGH +PLY ++ N + + Sbjct: 175 MVIDAGYDVPVLARLLDWIAVMTYDYHGQWDKKTGHVAPLYYHPDDD--TTYFNANYTIH 232 Query: 249 QWLQKGTPASKLILGMPTYGRSFTLASSSDTRVGAPATGSGTPGPFTKEGGMLAYYEVCS 308 W++KGTPASK+++GMP YG+SFT+ + + P + G PG +T+ G LAYYE+C Sbjct: 233 YWMEKGTPASKIVMGMPMYGQSFTIENRGIHGLNIPVSDGGEPGEYTRAKGFLAYYEICD 292 Query: 309 W---KGATKQRIQDQKV-PYIFRDNQWVGFDDVESFKTKVSYLKQKGLGGAMVWALDLDD 364 G T + Q++ PY ++ NQWV FDDVE K KV+++K LGG M+WALDLDD Sbjct: 293 RIRNSGWTVVKDPYQRMGPYAYKGNQWVSFDDVEIIKKKVNFIKSLNLGGGMIWALDLDD 352 Query: 365 FAGFSCNQGRYPLIQTLRQELSLP 388 + C QG++PL+ ++ EL P Sbjct: 353 YRN-RCGQGKHPLLNAIKTELLNP 375 >3W4R-A nrPDB Length = 554 Score = 292 bits (748), Expect = 2e-79, Method: Compositional matrix adjust. Identities = 165/416 (39%), Positives = 241/416 (57%), Gaps = 33/416 (7%) Query: 20 SAAKLVCYFTNWAQYRQGEARFLPKDLDPSLCTHLIYAFAGMTNHQLSTTEWN-----DE 74 S A++VCYF+NWA YR G R+ +D+ +CTH+IY+F G+T + D+ Sbjct: 23 SRARVVCYFSNWAVYRPGVGRYGIEDIPVDMCTHIIYSFIGVTEDTQQVLIIDPELDVDK 82 Query: 75 TLYQEFNGLKKMNPKLKTLLAIGGWNFGTQKFTDMVATANNRQTFVNSAIRFLRKYSFDG 134 ++ F L+ +P +K +A+GGW G K++ MVA + R FV S + FL KY+FDG Sbjct: 83 NGFKNFTSLRSKHPGVKFTVAVGGWAEGGSKYSKMVAAKSTRMAFVRSVVDFLNKYNFDG 142 Query: 135 LDLDWEYPGS--QGSPAVDKERFTTLVQDLANAFQQEAQTSGKERLLLSAAVPAGQTYVD 192 LDLDWEYPG+ +G DK++F LVQ+L AF +E + G E L+AAVP + Sbjct: 143 LDLDWEYPGAADRGGSFSDKDKFLYLVQELRRAFIREGK--GWE---LTAAVPLANFRLM 197 Query: 193 AGYEVDKIAQNLDFVNLMAYDFHGSWEKVTGHNSPLYKRQEESGAAASLNVDAAVQQWLQ 252 GY V ++ Q LD +++M+YD G+W +SPLYKR + A LNV+ +Q W Sbjct: 198 EGYHVPELCQELDAIHVMSYDLRGNWAGFADVHSPLYKRPHDQWAYEKLNVNDGLQLWED 257 Query: 253 KGTPASKLILGMPTYGRSFTLASSSD-----TRVGAPATGSGTPGPFTKEGGMLAYYEVC 307 KG P +KL++G+P YGRSFTL+S ++ T + A G G P P+T G AYYE+C Sbjct: 258 KGCPTNKLVVGIPFYGRSFTLSSGNNNYNLGTYINKEA-GGGDPAPYTNATGFWAYYEIC 316 Query: 308 SWKGA-----TKQRIQDQKVPYIFRDNQWVGFDDVESFKTKVSYLKQKGLGGAMVWALDL 362 + TK+ + K PY ++ QWVG++D S + K++++K+KG GAM WA+D+ Sbjct: 317 TEVDTADSKWTKKWDEHGKCPYAYKGTQWVGYEDPRSVEIKMNWIKEKGYLGAMTWAIDM 376 Query: 363 DDFAGFSCNQGRYPLIQTLRQELSLPYLP-------SGTPELEVPKPGQPSEPEHG 411 DDF G C + LI+ L + +S +P + TPE P P PS+P G Sbjct: 377 DDFQGL-CGEKNI-LIKLLHKHMSAYTVPPPRSGNTTPTPEWARP-PSTPSDPSEG 429 Score = 33.1 bits (74), Expect = 0.25, Method: Compositional matrix adjust. Identities = 20/70 (28%), Positives = 31/70 (44%), Gaps = 4/70 (5%) Query: 396 ELEVPKPGQPSEPEHGPSPGQDTFCQGKADGLYPNPRERSSFYSCAAGRLFQQSCPTGLV 455 E + P+ P+E E G S D C + D + P+ ++ ++ C G Q C G V Sbjct: 478 EAQQPEVELPAENEIGNS---DKICTSEEDYI-PDKKQCDKYWRCVNGEGMQFKCQPGTV 533 Query: 456 FSNSCKCCTW 465 F+ C W Sbjct: 534 FNVKLNVCDW 543 >3WKZ-A nrPDB Length = 395 Score = 285 bits (728), Expect = 3e-77, Method: Compositional matrix adjust. Identities = 155/389 (39%), Positives = 231/389 (59%), Gaps = 25/389 (6%) Query: 20 SAAKLVCYFTNWAQYRQGEARFLPKDLDPSLCTHLIYAFAGMTNHQLSTTEWN-----DE 74 S A++VCYF+NWA YR G R+ +D+ +CTH+IY+F G+T + D+ Sbjct: 5 SRARVVCYFSNWAVYRPGVGRYGIEDIPVDMCTHIIYSFIGVTEDTQQVLIIDPELDVDK 64 Query: 75 TLYQEFNGLKKMNPKLKTLLAIGGWNFGTQKFTDMVATANNRQTFVNSAIRFLRKYSFDG 134 ++ F L+ +P +K +A+GGW G K++ MVA + R FV S + FL KY+FDG Sbjct: 65 NGFKNFTSLRSKHPGVKFTVAVGGWAEGGSKYSKMVAAKSTRMAFVRSVVDFLNKYNFDG 124 Query: 135 LDLDWEYPGS--QGSPAVDKERFTTLVQDLANAFQQEAQTSGKERLLLSAAVPAGQTYVD 192 LDLDW+YPG+ +G DK++F LVQ+L AF +E + G E L+AAVP + Sbjct: 125 LDLDWQYPGAADRGGSFSDKDKFLYLVQELRRAFIREGK--GWE---LTAAVPLANFRLM 179 Query: 193 AGYEVDKIAQNLDFVNLMAYDFHGSWEKVTGHNSPLYKRQEESGAAASLNVDAAVQQWLQ 252 GY V ++ Q LD +++M+YD G+W +SPLYKR + A LNV+ +Q W Sbjct: 180 EGYHVPELCQELDAIHVMSYDLRGNWAGFADVHSPLYKRPHDQWAYEKLNVNDGLQLWED 239 Query: 253 KGTPASKLILGMPTYGRSFTLASSSD-----TRVGAPATGSGTPGPFTKEGGMLAYYEVC 307 KG P +KL++G+P YGRSFTL+S ++ T + A G G P P+T G AYYE+C Sbjct: 240 KGCPTNKLVVGIPFYGRSFTLSSGNNNYNLGTYINKEA-GGGDPAPYTNATGFWAYYEIC 298 Query: 308 SWKGA-----TKQRIQDQKVPYIFRDNQWVGFDDVESFKTKVSYLKQKGLGGAMVWALDL 362 + TK+ + K PY ++ QWVG++D S + K++++K+KG GAM WA+D+ Sbjct: 299 TEVDTADSKWTKKWDEHGKCPYAYKGTQWVGYEDPRSVEIKMNWIKEKGYLGAMTWAIDM 358 Query: 363 DDFAGFSCNQGRYPLIQTLRQELSLPYLP 391 DDF G C + + LI+ L + +S +P Sbjct: 359 DDFQGL-CGE-KNILIKLLHKHMSAYTVP 385 >5Y2C-A nrPDB Length = 383 Score = 273 bits (699), Expect = 9e-74, Method: Compositional matrix adjust. Identities = 147/378 (38%), Positives = 214/378 (56%), Gaps = 26/378 (6%) Query: 23 KLVCYFTNWAQYRQGEARFLPKDLDPSLCTHLIYAFAGMTNHQL---STTEWND--ETLY 77 K+VCY+TNWA YR ++ P D++P LCTH+IYAFA + +L S W D Y Sbjct: 4 KVVCYYTNWAWYRPDNGKYTPGDINPELCTHIIYAFAVLDKEELVIKSHDIWLDVENKFY 63 Query: 78 QEFNGLKKMNPKLKTLLAIGGWNFGT-QKFTDMVATANNRQTFVNSAIRFLRKYSFDGLD 136 ++ LK +K LL +GGW+ K++ +V + R+ FV A+ FL +Y FDGLD Sbjct: 64 EKVTALKSHG--VKVLLGLGGWDDSAGDKYSRLVNNVSARRKFVVHAVDFLEQYGFDGLD 121 Query: 137 LDWEYPGS-----QGSPAVDKERFTTLVQDLANAFQQEAQTSGKERLLLSAAVPAGQTYV 191 LDW YP + P DK+ F LV++L AF + +LLSAAV A + + Sbjct: 122 LDWLYPKCWQVECEKGPDSDKQGFADLVKELRKAFNRRG-------MLLSAAVSASKRVI 174 Query: 192 DAGYEVDKIAQNLDFVNLMAYDFHGSWEKVTGHNSPLYKRQEESGAAASLNVDAAVQQWL 251 D Y V ++ NLD+++LM YD+HG W+K TGH +P+Y +++ + NV+ V W+ Sbjct: 175 DYAYNVPALSMNLDWISLMTYDYHGQWDKKTGHVAPMYVHDKDTD--NTFNVNFTVNYWI 232 Query: 252 QKGTPASKLILGMPTYGRSFTLASSSDTRVGAPATGSGTPGPFTKEGGMLAYYEVCS--- 308 KG KL++G+P YG+SF++ + T +GAP G G T+ G L++YE+C Sbjct: 233 NKGADRKKLVVGVPFYGQSFSVVEGAGTGLGAPTYAGGEAGDETRARGFLSFYEICERVK 292 Query: 309 WKGATKQRIQDQKV-PYIFRDNQWVGFDDVESFKTKVSYLKQKGLGGAMVWALDLDDFAG 367 KG R ++ PY D+QWV FDD + K Y++ LGG+M W+LDLDDF G Sbjct: 293 VKGWKVHRDPGGRIGPYATHDDQWVSFDDDFMARHKAEYVRAMELGGSMAWSLDLDDFTG 352 Query: 368 FSCNQGRYPLIQTLRQEL 385 C G+ PL+ T+ L Sbjct: 353 KYCGCGKAPLLTTINHVL 370 >1ITX-A nrPDB Length = 419 Score = 205 bits (522), Expect = 3e-53, Method: Compositional matrix adjust. Identities = 134/402 (33%), Positives = 199/402 (49%), Gaps = 69/402 (17%) Query: 23 KLVCYFTNWAQYRQGEARFLPKDLDPSLCTHLIYAFAGM--------------------- 61 K+V Y+ +WA Y + + D+DP+ TH+ YAFA + Sbjct: 13 KIVGYYPSWAAYGR---NYNVADIDPTKVTHINYAFADICWNGIHGNPDPSGPNPVTWTC 69 Query: 62 -----------------------TNHQLSTTEWNDETL--YQEFNGLKKMNPKLKTLLAI 96 T + W+ + N LK+ NP LKT++++ Sbjct: 70 QNEKSQTINVPNGTIVLGDPWIDTGKTFAGDTWDQPIAGNINQLNKLKQTNPNLKTIISV 129 Query: 97 GGWNFGTQKFTDMVATANNRQTFVNSAIRFLRKYSFDGLDLDWEYPGSQGSPA-----VD 151 GGW + + +F+D+ ATA R+ F NSA+ FLRKY+FDG+DLDWEYP S G D Sbjct: 130 GGWTW-SNRFSDVAATAATREVFANSAVDFLRKYNFDGVDLDWEYPVSGGLDGNSKRPED 188 Query: 152 KERFTTLVQDLANAFQQEAQTSGKERLLLSAAVPAGQTYVDAGYEVDKIAQNLDFVNLMA 211 K+ +T L+ + GK + LL+ A A TY A E+ KIA +D++N+M Sbjct: 189 KQNYTLLLSKIREKLDAAGAVDGK-KYLLTIASGASATYA-ANTELAKIAAIVDWINIMT 246 Query: 212 YDFHGSWEKVTGHNSPLYKRQEESGA----AASLNVDAAVQQWLQKGTPASKLILGMPTY 267 YDF+G+W+K++ HN+PL S A A + NV A Q L G PA+KL+LG+P Y Sbjct: 247 YDFNGAWQKISAHNAPLNYDPAASAAGVPDANTFNVAAGAQGHLDAGVPAAKLVLGVPFY 306 Query: 268 GRSFTLASSSDTRVGAPATGSGTPGPFTKEGGMLAYYEV----CSWKGATKQRIQDQKVP 323 GR + + + TG + G T E G +Y++ + G T+ KVP Sbjct: 307 GRGWDGCAQAGNGQYQTCTGGSSVG--TWEAGSFDFYDLEANYINKNGYTRYWNDTAKVP 364 Query: 324 YIFR--DNQWVGFDDVESFKTKVSYLKQKGLGGAMVWALDLD 363 Y++ + +++ +DD ES K +Y+K KGLGGAM W L D Sbjct: 365 YLYNASNKRFISYDDAESVGYKTAYIKSKGLGGAMFWELSGD 406 >4MNK-A nrPDB Length = 348 Score = 205 bits (521), Expect = 4e-53, Method: Compositional matrix adjust. Identities = 128/342 (37%), Positives = 192/342 (56%), Gaps = 27/342 (7%) Query: 31 WAQYRQGEARFLPKDLDPSLCTHLIYAFAGMT--NHQLSTTEWNDETLYQEFNGLKKMNP 88 W Y E F P ++ L THL YAFA + ++ +++T ++++NP Sbjct: 10 WPAYSVSE--FPPSKINSRLFTHLYYAFAELNAPTFEVRVPPGSEKTAEDFTPTVRRLNP 67 Query: 89 KLKTLLAIGGWNFGTQ-KFTDMVATANNRQTFVNSAIRFLRKYSFDGLDLDWEYPGSQGS 147 +KTL++IGG + F + + A+ RQ FV S+I R+Y F GLDLD+EYP Sbjct: 68 SVKTLISIGGGGSEVRDNFAKLNSDASARQRFVKSSIALARRYGFHGLDLDYEYP----E 123 Query: 148 PAVDKERFTTLVQDLANAFQQEAQTSGKERLLLSAAVPAGQTY----VDAGYEVDKIAQN 203 P ++ E F LV +L A ++EA+TSGK RLLL+ AV Q V Y V IA Sbjct: 124 PQLEMENFVKLVSELTAAIREEARTSGKPRLLLTEAVYFHQKLFPWEVVTEYPVQFIAAG 183 Query: 204 LDFVNLMAYDFHGSWEKVTGHNSPLYKRQEESGAAASLNVDAAVQQWLQKGTPASKLILG 263 LD+VN+MAYDFHGSWE TG +P R S AS+ +++ +L G P KL+LG Sbjct: 184 LDWVNVMAYDFHGSWENFTG--APAALRDPNSKFTASVGIES----FLAAGMPPEKLVLG 237 Query: 264 MPTYGRSFTLASSSDTRVGAPATGSGTPGPFTKEGGMLAYYEVCSW-KGATKQRIQDQKV 322 +P +GRS+ L ++++ +GAPA G+G G L++ E+ ++ +G ++ V Sbjct: 238 IPLFGRSWLLKNNNEVGIGAPAVGAG------PVDGALSFSEIQNFIRGGAREVFDTTTV 291 Query: 323 -PYIFRDNQWVGFDDVESFKTKVSYLKQKGLGGAMVWALDLD 363 Y ++DN WVG+D+ +S KV Y K+K LGG W+++ D Sbjct: 292 SAYAYKDNVWVGYDNQQSVALKVQYAKEKRLGGYFFWSVNQD 333 >6BT9-A nrPDB Length = 672 Score = 201 bits (512), Expect = 4e-52, Method: Compositional matrix adjust. Identities = 141/442 (31%), Positives = 202/442 (45%), Gaps = 88/442 (19%) Query: 23 KLVCYFTNWAQYRQGEARFLPKDLDPSLCTHLIYAFAGM--------------------- 61 K+V YF +W Y + + D+D S THL YAFA + Sbjct: 38 KIVGYFPSWGVYGR---NYQVADIDASKLTHLNYAFADICWNGKHGNPSTHPDNPNKQTW 94 Query: 62 -----------------------------TNHQLSTTEWNDETLYQ------EFNGLKKM 86 ++ +S T W D Y E LK Sbjct: 95 NCKESGVPLQNKEVPNGTLVLGEPWADVTKSYPVSGTTWEDCDKYARCGNFGELKRLKAK 154 Query: 87 NPKLKTLLAIGGWNFGTQKFTDMVATANNRQTFVNSAIRFLRKYSFDGLDLDWEYPGSQG 146 P LKT++++GGW + + +F+DM A R+ F S + FLR Y FDG+DLDWEYPG + Sbjct: 155 YPHLKTIISVGGWTW-SNRFSDMAADEKTRKVFAESTVAFLRAYGFDGVDLDWEYPGVET 213 Query: 147 SPA-----VDKERFTTLVQDLANAFQQEAQTSGKERLLLSAAVPAGQTYVDAGYEVDKIA 201 P DK+ FT L+QD+ NA + GK+ LL+ A A Q Y D E+ KI+ Sbjct: 214 IPGGSYRPEDKQNFTLLLQDVRNALNKAGAEDGKQ-YLLTIASGASQRYADH-TELKKIS 271 Query: 202 QNLDFVNLMAYDFHGSWEKVTGHNSPLYKRQEESGAAASLNVDAAVQQWLQKGTPASKLI 261 Q LD++N+M YDFHG WE + HN+ LYK + A + VD A+ + +G P KL+ Sbjct: 272 QILDWINIMTYDFHGGWEATSNHNAALYKDPNDPAANTNFYVDGAINVYTNEGVPVDKLV 331 Query: 262 LGMPTYGRSFTLASSSDTRVGAPATGSGTPGPFTKEG----------GMLAYYEVCS--- 308 LG+P YGR + + P G+ G +G G+ Y ++ + Sbjct: 332 LGVPFYGRGWKSCGKENNGQYQPCK-PGSDGKLASKGTWDDYSTGDTGVYDYGDLAANYV 390 Query: 309 -WKGATKQRIQDQKVPYIFR--DNQWVGFDDVESFKTKVSYLKQKGLGGAMVWAL--DLD 363 G + KVPY++ ++ +DD ES K K Y+K KGL GAM W L D Sbjct: 391 NKNGFVRYWNDTAKVPYLYNATTGTFISYDDNESMKYKTDYIKTKGLSGAMFWELSGDCR 450 Query: 364 DFAGFSCNQGRYPLIQTLRQEL 385 +SC+ + L+ TL +EL Sbjct: 451 TSPKYSCSGPK--LLDTLVKEL 470 >3AQU-A nrPDB Length = 356 Score = 199 bits (506), Expect = 2e-51, Method: Compositional matrix adjust. Identities = 126/344 (36%), Positives = 182/344 (52%), Gaps = 20/344 (5%) Query: 32 AQYRQGEARFLPKDLDPSLCTHLIYAFAGMTN--HQLSTTEWNDETLYQEFNGLKKMNPK 89 A Y + F D+D SL THL AFA + + +Q++ + N +++ NP Sbjct: 7 ASYWFPASEFPVTDIDSSLFTHLFCAFADLNSQTNQVTVSSANQPKFSTFTQTVQRRNPS 66 Query: 90 LKTLLAIGGWNFGTQKFTDMVATANNRQTFVNSAIRFLRKYSFDGLDLDWEYPGSQGSPA 149 +KTLL+IGG + M + +R++F++S+IR R Y F GLDLDWEYP S A Sbjct: 67 VKTLLSIGGGIADKTAYASMASNPTSRKSFIDSSIRVARSYGFHGLDLDWEYPSS----A 122 Query: 150 VDKERFTTLVQDLANAFQQEAQTSGKERLLLSAAVPAGQTYVDAGYEVDKIAQNLDFVNL 209 + F TL+++ +A EA +SGK RLLL+AAV Y Y V +A +LD+VNL Sbjct: 123 TEMTNFGTLLREWRSAVVAEASSSGKPRLLLAAAVFYSNNYYSVLYPVSAVASSLDWVNL 182 Query: 210 MAYDFHG-SWEKVTGHNSPLYKRQEESGAAASLNVDAAVQQWLQKGTPASKLILGMPTYG 268 MAYDF+G W +VTG + L+ + S A S DA + W+Q G PA K +LG P YG Sbjct: 183 MAYDFYGPGWSRVTGPPAALF---DPSNAGPS--GDAGTRSWIQAGLPAKKAVLGFPYYG 237 Query: 269 RSFTLASSSDTRVGAPATGSGTPGPFTKEGGMLAYYEVCSW---KGATKQRIQDQKVPYI 325 ++ L +++ AP TG+ G + Y ++ + GAT Y Sbjct: 238 YAWRLTNANSHSYYAPTTGAA-----ISPDGSIGYGQIRKFIVDNGATTVYNSTVVGDYC 292 Query: 326 FRDNQWVGFDDVESFKTKVSYLKQKGLGGAMVWALDLDDFAGFS 369 + W+G+DD +S TKV Y KQ+GL G W + DD +G S Sbjct: 293 YAGTNWIGYDDNQSIVTKVRYAKQRGLLGYFSWHVGADDNSGLS 336 >5GZU-A nrPDB Length = 885 Score = 180 bits (456), Expect = 1e-45, Method: Compositional matrix adjust. Identities = 126/400 (31%), Positives = 188/400 (47%), Gaps = 55/400 (13%) Query: 23 KLVCYFTNWAQYRQGEARFLPKDLDPSLCTHLIYAFAGMTNHQLSTTE----WN------ 72 K+V Y W + + E + +D + THL YAF + N ++ T + W Sbjct: 27 KIVSYIPAWVDWAKDE-----RGVDATKFTHLYYAFGRINNGKVVTIKEDAKWTEDPTIT 81 Query: 73 -----------DETLYQEFNGLKKMNPKLKTLLAIGGWNFGTQKFTDMVATANNRQTFVN 121 DE+ GLK NP LK L++IGGW + F+D T +R+ F N Sbjct: 82 EADRIKRRNNPDESNLAYLTGLKAKNPNLKVLVSIGGWE--AEGFSDAALTPESREVFAN 139 Query: 122 SAIRFLRKYSFDGLDLDWEYP-----GSQGSPAVDKERFTTLVQDLANAFQQEAQTSGKE 176 SA+ F+ KY+ DG+DLDWEYP G S DK FT L++ L ++ T+ K Sbjct: 140 SALDFMNKYNLDGIDLDWEYPVYGAWGVIKSRPEDKANFTALLKLLREKLDAQSTTTNK- 198 Query: 177 RLLLSAAVPAGQTYVDAGYEVDKIAQNLDFVNLMAYDFHGSWEKVTGHNSPLYKRQEESG 236 L+ A A +TY D+ E+ KI LD++NLM YD HG W+ T H++ +Y S Sbjct: 199 YYELAIAAGASKTYTDS-VELTKITPYLDYINLMTYDLHGGWDPATSHHTAVY-----SA 252 Query: 237 AAASLNVDAAVQQWLQKGTPASKLILGMPTYGRSFTLASSSDTRVGAPA-TGSGTPGPFT 295 L+VD+ V+ +L G PA KL++G Y R + + T + A + +G+PG Sbjct: 253 TNNQLSVDSTVKLYLNNGVPAEKLMVGGAFYSRVWQNVENKGTGLSEKAGSQAGSPGTIV 312 Query: 296 KEGGMLAYYEVCSWKGATKQRIQDQKVPYIFRDNQWVGFDDVESFKTKVSYLKQKGLGGA 355 + Y + G T+ K PY+F + ++ ++D S K Y+KQ L G Sbjct: 313 YSELVNNY---INKNGYTRYWDDTAKAPYLFNGSTFISYEDTASAAYKAEYIKQNNLAGF 369 Query: 356 MVWALDLDDFAGFSCNQGRYPLIQTLRQELSLPYLPSGTP 395 M W +S + + L T+ L Y SGTP Sbjct: 370 MYWE--------YSQDSDSHELANTIYSRL---YAKSGTP 398 Score = 161 bits (408), Expect = 5e-40, Method: Compositional matrix adjust. Identities = 115/370 (31%), Positives = 175/370 (47%), Gaps = 56/370 (15%) Query: 24 LVCYFTNWAQYRQGEARFLPKDLDPSLCTHLIYAFAGMTNHQL----STTEWNDETLYQE 79 L+ Y W + + +D + TH+ YAFA + ++++ W +E +E Sbjct: 515 LLGYVPGWVDWTNSAYK-----VDATKLTHINYAFARIKDNKVVKISEDINWVNEFPSEE 569 Query: 80 ----------------FNGLKKMNPKLKTLLAIGGWNFGTQKFTDMVATANNRQTFVNSA 123 LK+ NP LK L++IGGW + F+D T R+ NSA Sbjct: 570 IREQRRNNPDDANFAYLKTLKQQNPSLKVLVSIGGW--AAEGFSDAALTPETREELANSA 627 Query: 124 IRFLRKYSFDGLDLDWEYP-----GSQGSPAVDKERFTTLVQDLANAFQQEAQTSGK--E 176 I F+ +Y FDG+DLDWEYP G S DK+ FT L++ E GK E Sbjct: 628 IAFMHQYGFDGIDLDWEYPVYGAFGVIKSRPEDKQNFTALLKLFREKLDVEGALHGKYYE 687 Query: 177 RLLLSAAVPAGQTYVDAGYEVDKIAQNLDFVNLMAYDFHGSWEKVTGHNSPLYKRQEESG 236 + SAA P Y+++ E+DKI Q LD++++M YD+HGSWE T H + +Y G Sbjct: 688 LAIASAAAP---IYINS-VELDKIHQYLDYMSVMTYDYHGSWESKTAHQASVYTSALSPG 743 Query: 237 AAASLNVDAAVQQWLQKGTPASKLILGMPTYGRSFTLASSSD----TRVGAPATGSGTPG 292 + D+ + + ++G PASKL++G Y R + + + + G A GTP Sbjct: 744 ---DFSADSVLTAYRKQGVPASKLVIGGAFYARGWVNVPNINHGLFQQAGDQAKNPGTP- 799 Query: 293 PFTKEGGMLAYYEVCSWKGATKQRIQDQKVPYIFRDN----QWVGFDDVESFKTKVSYLK 348 T + Y++ KG T+ K PY++ + ++ +DD ES K K Y K Sbjct: 800 --TYNDLVKDYFD----KGYTRYWDNSAKAPYLYNPDANGGTFITYDDEESLKYKAEYAK 853 Query: 349 QKGLGGAMVW 358 +GL G M W Sbjct: 854 NQGLRGVMFW 863 >6EPB-A nrPDB Length = 423 Score = 171 bits (434), Expect = 5e-43, Method: Compositional matrix adjust. Identities = 116/360 (32%), Positives = 171/360 (47%), Gaps = 40/360 (11%) Query: 26 CYFTNWAQYRQGEARFLPKDLDPSLCTHLIYAFAGMT--------------NHQLSTTEW 71 YFTNW Y + F P DL S TH+IY+F + + W Sbjct: 42 VYFTNWGIY---DRNFQPADLVASDVTHVIYSFMNLQADGTVISGDTYADYEKHYADDSW 98 Query: 72 NDETL-----YQEFNGLKKMNPKLKTLLAIGGWNFGTQKFTDMVATANNRQTFVNSAIRF 126 ND ++ +KK N LK LL+IGGW + T F +T NR+ F +AI F Sbjct: 99 NDVGTNAYGCVKQLFKVKKANRGLKVLLSIGGWTWSTN-FPSAASTDANRKNFAKTAITF 157 Query: 127 LRKYSFDGLDLDWEYPGSQGSPAVDKERFTTLVQDLANAFQQ-EAQTSGKERLLLSAAVP 185 ++ + FDG+D+DWEYP + A L++++ + AQ + LL+ A P Sbjct: 158 MKDWGFDGIDIDWEYP----ADATQASNMILLLKEVRSQLDAYAAQYAPGYHFLLTIAAP 213 Query: 186 AGQTYVDAGYEVDKIAQNLDFVNLMAYDFHGSWEKVTGHNSPLYKRQEESGAAASLNVDA 245 AG+ + + + Q LD++NLMAYD+ GS+ +TGH++ L+ A N D+ Sbjct: 214 AGKDNY-SKLRLADLGQVLDYINLMAYDYAGSFSPLTGHDANLFNNPSNPNATP-FNTDS 271 Query: 246 AVQQWLQKGTPASKLILGMPTYGRSFTLASSSDTRVGAPATGSGTPGPFTKEGGMLAYYE 305 AV+ ++ G PA+K++LGMP YGRSF + +GS G + Y+ Sbjct: 272 AVKDYINGGVPANKIVLGMPIYGRSFQNTAGIGQTYNGVGSGSWEAGIWD--------YK 323 Query: 306 VCSWKGATKQRIQDQKVPYIFRD--NQWVGFDDVESFKTKVSYLKQKGLGGAMVWALDLD 363 GAT Q K Y + + + FD + TKV+YLK GLGG+M W D Sbjct: 324 ALPKAGATVQYDSVAKGYYSYNSATKELISFDTPDMINTKVAYLKSLGLGGSMFWEASAD 383 >3G6L-A nrPDB Length = 406 Score = 170 bits (430), Expect = 1e-42, Method: Compositional matrix adjust. Identities = 122/367 (33%), Positives = 170/367 (46%), Gaps = 54/367 (14%) Query: 26 CYFTNWAQYRQGEARFLPKDLDPSLCTHLIYAFAGM--------------TNHQLSTTEW 71 YFTNW Y + F P DL S H++Y+F + S W Sbjct: 25 VYFTNWGIYGR---NFQPADLQASKILHVLYSFMNLRVDGTVYSGDTYADLEKHYSDDSW 81 Query: 72 ND---------ETLYQEFNGLKKMNPKLKTLLAIGGWNFGTQKFTDMVATANNRQTFVNS 122 ND + LY+ LKK N LK +L+IGGW + T F +T R TF + Sbjct: 82 NDIGTNAYGCVKQLYK----LKKANRSLKIMLSIGGWTWSTN-FPAAASTEATRATFAKT 136 Query: 123 AIRFLRKYSFDGLDLDWEYPGSQGSPAVDKERFTTLVQDLANAFQQEAQT-SGKERLLLS 181 A+ F++ + FDG+D+DWEYP S+ D L+Q + + T + LS Sbjct: 137 AVEFMKDWGFDGIDVDWEYPASE----TDANNMVLLLQRVRQELDSYSATYANGYHFQLS 192 Query: 182 AAVPAGQTYVDAGYEVDKIAQ---NLDFVNLMAYDFHGSWEKVTGHNSPLYKRQEESGAA 238 A PAG ++ Y V K+AQ LD +NLMAYD+ GSW+ V+GH + LY ++ Sbjct: 193 IAAPAGPSH----YNVLKLAQLGSVLDNINLMAYDYAGSWDSVSGHQTNLYPSTSNP-SS 247 Query: 239 ASLNVDAAVQQWLQKGTPASKLILGMPTYGRSFTLASSSDTRVGAPATGSGTPGPFTKEG 298 + AAV ++ G PASK+ILGMP YGR+F P T G + E Sbjct: 248 TPFSTKAAVDAYIAAGVPASKIILGMPIYGRAF-------VGTDGPGKPYSTIGEGSWES 300 Query: 299 GMLAYYEVCSWKGATKQRIQDQKVPYIFRDNQ--WVGFDDVESFKTKVSYLKQKGLGGAM 356 G+ Y+V GAT Y + + + +D + +TKVSY K GLGG+M Sbjct: 301 GIWD-YKVLPKAGATVITDSAAGATYSYDSSSRTMISYDTPDMVRTKVSYAKGLGLGGSM 359 Query: 357 VWALDLD 363 W D Sbjct: 360 FWEASAD 366 >3ALF-A nrPDB Length = 353 Score = 170 bits (430), Expect = 1e-42, Method: Compositional matrix adjust. Identities = 105/333 (31%), Positives = 174/333 (52%), Gaps = 19/333 (5%) Query: 44 KDLDPSLCTHLIYAFAGMTN--HQLSTTEWNDETLYQEFNGLKKMNPKLKTLLAIGGWNF 101 ++D +L THL AFA + +QL + N ++ Q + +++ NP +KT L+I G Sbjct: 18 NNIDSTLFTHLFCAFADLNPQLNQLIISPENQDSFRQFTSTVQRKNPSVKTFLSIAGGRA 77 Query: 102 GTQKFTDMVATANNRQTFVNSAIRFLRKYSFDGLDLDWEYPGSQGSPAVDKERFTTLVQD 161 + + M N+R++F++S+IR R+ F GLDLDWEYP S A D TL+ + Sbjct: 78 NSTAYGIMARQPNSRKSFIDSSIRLARQLGFHGLDLDWEYPLS----AADMTNLGTLLNE 133 Query: 162 LANAFQQEAQTSGKERLLLSAAVPAGQTYVDAGYEVDKIAQNLDFVNLMAYDFHG-SWE- 219 A EA+ SG+ LLL+AAV Y V+ +A+NLD++NLMAYDF+G +W Sbjct: 134 WRTAINTEARNSGRAALLLTAAVSNSPRVNGLNYPVESLARNLDWINLMAYDFYGPNWSP 193 Query: 220 KVTGHNSPLYKRQEESGAAASLNVDAAVQQWLQKGTPASKLILGMPTYGRSFTLASSSDT 279 T ++ L+ + +N W+Q G P KL+LG+P YG ++ L +++ Sbjct: 194 SQTNSHAQLFDPVNHVSGSDGINA------WIQAGVPTKKLVLGIPFYGYAWRLVNANIH 247 Query: 280 RVGAPATGSGTPGPFTKEGGMLAYYEVCSWKGATK-QRIQDQKV--PYIFRDNQWVGFDD 336 + APA G G + G + Y + + ++ + + + Y + + W+ +DD Sbjct: 248 GLRAPAAGKSNVGAV--DDGSMTYNRIRDYIVESRATTVYNATIVGDYCYSGSNWISYDD 305 Query: 337 VESFKTKVSYLKQKGLGGAMVWALDLDDFAGFS 369 ++ + KV+Y+K +GL G W + D G S Sbjct: 306 TQTVRNKVNYVKGRGLLGYFAWHVAGDQNWGLS 338 >1LL6-A nrPDB Length = 392 Score = 161 bits (407), Expect = 7e-40, Method: Compositional matrix adjust. Identities = 110/357 (30%), Positives = 178/357 (49%), Gaps = 42/357 (11%) Query: 25 VCYFTNWAQYRQGEARFLPKDLDPSLCTHLIYAFAGM--------------TNHQLSTTE 70 V YF NWA Y +G P+DL TH++YAFA + T+ + Sbjct: 6 VVYFVNWAIYGRGHN---PQDLKADQFTHILYAFANIRPSGEVYLSDTWADTDKHYPGDK 62 Query: 71 WND--ETLY---QEFNGLKKMNPKLKTLLAIGGWNFGTQKFTDMVATANNRQTFVNSAIR 125 W++ +Y ++ LKK N LKTLL+IGGW + + F +T R+ F +++++ Sbjct: 63 WDEPGNNVYGCIKQMYLLKKNNRNLKTLLSIGGWTY-SPNFKTPASTEEGRKKFADTSLK 121 Query: 126 FLRKYSFDGLDLDWEYPGSQGSPAVDKERFTTLVQDLANAFQQ-EAQTSGKERLLLSAAV 184 ++ FDG+D++WEYP + F L++ A A+ ++ LL+ A Sbjct: 122 LMKDLGFDGIDINWEYPEDEKQA----NDFVLLLKACREALDAYSAKHPNGKKFLLTIAS 177 Query: 185 PAG-QTYVDAGYEVDKIAQNLDFVNLMAYDFHGSWEKVTGHNSPLYKRQEESGAAASLNV 243 PAG Q Y ++ ++ + LDF NLMAYDF GSW+KV+GH S ++ + + + Sbjct: 178 PAGPQNY--NKLKLAEMDKYLDFWNLMAYDFSGSWDKVSGHMSNVFPSTTKP-ESTPFSS 234 Query: 244 DAAVQQWLQKGTPASKLILGMPTYGRSFTLASSSDTRVGAPATGSGTPGPFTKEGGMLAY 303 D AV+ +++ G PA+K++LGMP YGR+F T GS E G+ Y Sbjct: 235 DKAVKDYIKAGVPANKIVLGMPLYGRAFASTDGIGTSFNGVGGGSW-------ENGVWDY 287 Query: 304 YEVCSWKGATKQRIQDQKVPYIFRDNQ--WVGFDDVESFKTKVSYLKQKGLGGAMVW 358 ++ +GA ++D Y + N+ + +D V+ K Y+ + G+GG M W Sbjct: 288 KDMPQ-QGAQVTELEDIAASYSYDKNKRYLISYDTVKIAGKKAEYITKNGMGGGMWW 343 >4URI-A nrPDB Length = 337 Score = 160 bits (405), Expect = 1e-39, Method: Compositional matrix adjust. Identities = 109/326 (33%), Positives = 170/326 (52%), Gaps = 27/326 (8%) Query: 45 DLDPSLCTHLIYAFAGM--TNHQLSTTEWNDETLYQEFNGLKKMNPKLKTLLAIGGWNFG 102 D++PS THL AFA + ++L+ + N ++ NP +KTLL+IGG Sbjct: 17 DINPSHFTHLFCAFADLDPNTNKLTISSSNAAAFSTFTQTVRAKNPSVKTLLSIGGGGGR 76 Query: 103 T--QKFTDMVATANNRQTFVNSAIRFLRKYSFDGLDLDWEYPGSQGSPAVDKERFTTLVQ 160 F +M + A+ R++F++S+I+ R+ +F GLDLDWEYP S +DK F +L++ Sbjct: 77 ALAAVFANMASQASRRKSFIDSSIQLARRNNFHGLDLDWEYPSSD----IDKTNFASLIR 132 Query: 161 DLANAFQQEAQTSGKERLLLSAAV-PAGQTYVDAGYEVDKIAQNLDFVNLMAYDFH--GS 217 + A E+ TSG LLLSAAV + Q Y + IA NLD+VN+M YD + S Sbjct: 133 EWRAAVATESSTSGTPALLLSAAVGGSDQITPLKYYPGEAIANNLDWVNVMTYDLYTSDS 192 Query: 218 WEKVTGHNSPLYKRQEESGAAASLNVDAAVQQWLQKGTPASKLILGMPTYGRSFTLASSS 277 + +T +PL+ + + D + +W+Q G P SKL LG+P YG + L+ + Sbjct: 193 YPTLTQPPAPLFYPR------GIFSADEGITKWIQSGVPESKLALGLPFYGFKWRLSDPN 246 Query: 278 DTRVGAPATGSGTPGPFTKEGGMLAYYEVCSWKGATKQRIQDQKVPYIFRDNQWVGFDDV 337 + + APA T+ G + Y ++ + G + Y F+ W G+DD Sbjct: 247 NHGLFAPA---------TQGLGAVKYKDIVN-TGGQVEFDSTYVTNYRFKGTDWYGYDDT 296 Query: 338 ESFKTKVSYLKQKGLGGAMVWALDLD 363 +S KV+Y KQ+GL G W ++ D Sbjct: 297 QSISAKVAYAKQRGLFGYFAWHIEQD 322 >3CHF-A nrPDB Length = 433 Score = 156 bits (394), Expect = 2e-38, Method: Compositional matrix adjust. Identities = 116/362 (32%), Positives = 171/362 (47%), Gaps = 41/362 (11%) Query: 20 SAAKLVCYFTNWAQYRQGEARFLPKDLDPSLCTHLIYAFAGM---TNHQLSTTEWND-ET 75 S + V YF NWA Y + P+DL TH++YAFA + T T W D E Sbjct: 41 SGYRSVVYFVNWAIYGRNHN---PQDLPVERLTHVLYAFANVRPETGEVYMTDSWADIEK 97 Query: 76 LY----------------QEFNGLKKMNPKLKTLLAIGGWNFGTQKFTDMVATANNRQTF 119 Y ++ LKK N LK LL+IGGW + + F +T R+ F Sbjct: 98 HYPGDSWSDTGNNVYGCIKQLYLLKKQNRNLKVLLSIGGWTY-SPNFAPAASTDAGRKNF 156 Query: 120 VNSAIRFLRKYSFDGLDLDWEYPGSQGSPAVDKERFTTLVQDLANAFQQ-EAQTSGKERL 178 +A++ L+ FDGLD+DWEYP + F L++++ A A +G + Sbjct: 157 AKTAVKLLQDLGFDGLDIDWEYPENDQQ----ANDFVLLLKEVRTALDSYSAANAGGQHF 212 Query: 179 LLSAAVPAGQTYVDAGYEVDKIAQNLDFVNLMAYDFHGSWEKVTGHNSPLYKRQEESGAA 238 LL+ A PAG + + D + Q LDF NLMAYD+ GS+ ++GH + +Y + + Sbjct: 213 LLTVASPAGPDKIKVLHLKD-MDQQLDFWNLMAYDYAGSFSSLSGHQANVYN-DTSNPLS 270 Query: 239 ASLNVDAAVQQWLQKGTPASKLILGMPTYGRSFTLASSSDTRVGAPATGSGTPGPFTKEG 298 N A+ + G PA+K++LGMP YGRSF ++ G P G G + E Sbjct: 271 TPFNTQTALDLYRAGGVPANKIVLGMPLYGRSF----ANTDGPGKPYNGVGQG---SWEN 323 Query: 299 GMLAYYEVCSWKGATKQRIQDQKVPYIFRDNQ--WVGFDDVESFKTKVSYLKQKGLGGAM 356 G+ Y+ GAT+ + D Y + + +D+ + K Y+K GLGGAM Sbjct: 324 GVWD-YKALPQAGATEHVLPDIMASYSYDATNKFLISYDNPQVANLKSGYIKSLGLGGAM 382 Query: 357 VW 358 W Sbjct: 383 WW 384 >1JNE-A nrPDB Length = 420 Score = 152 bits (384), Expect = 3e-37, Method: Compositional matrix adjust. Identities = 124/432 (28%), Positives = 202/432 (46%), Gaps = 79/432 (18%) Query: 21 AAKLVCYFTNWAQYRQGEARFLPKDLDPSL--CTHLIYAFAGMTNHQLSTTEWND----- 73 A+ LVCY+ + + R+G + L DL+ +L C+HL+Y +AG+ L N+ Sbjct: 1 ASNLVCYYDSSSYTREGLGKLLNPDLEIALQFCSHLVYGYAGLRGENLQAYSMNENLDIY 60 Query: 74 ETLYQEFNGLKKMNPKLKTLLAIGGWNF----GTQKFTDMVATANNRQT-FVNSAIRFLR 128 + + E LK+ P LK LL++GG + K+ D++ RQ F+ SA ++ Sbjct: 61 KHQFSEVTSLKRKYPHLKVLLSVGGDHDIDPDHPNKYIDLLEGEKVRQIGFIRSAYELVK 120 Query: 129 KYSFDGLDLDWEYP--------GSQG------------------SPAVDKERFTTLVQDL 162 Y FDGLDL +++P G G A+ KE+FT LV+D+ Sbjct: 121 TYGFDGLDLAYQFPKNKPRKVHGDLGLAWKSIKKLFTGDFIVDPHAALHKEQFTALVRDV 180 Query: 163 ANAFQQEAQTSGKERLLLSAAVPAGQTYVDAGYEVDKIAQN--LDFVNLMAYDFHGSWE- 219 ++ + + LLS V V++ + D A N +DFVNL +DF Sbjct: 181 KDSLRADG-------FLLSLTVLPN---VNSTWYFDIPALNGLVDFVNLATFDFLTPARN 230 Query: 220 -KVTGHNSPLYKRQEESGAAASLNVDAAVQQWLQKGTPASKLILGMPTYGRSFTLASSSD 278 + +++P+Y A LN D V+ WL +G P++K+ LG+ TYG ++ L S Sbjct: 231 PEEADYSAPIYHPDGSKDRLAHLNADFQVEYWLSQGFPSNKINLGVATYGNAWKLTKDSG 290 Query: 279 TRVGAPA----TGSGTPGPFTKEGGMLAYYEVCS---------WKG--ATKQRIQDQK-- 321 G P +G G +++ G+L+Y E+C KG + +R+ D Sbjct: 291 LE-GVPVVPETSGPAPEGFQSQKPGLLSYAEICGKLSNPQNQFLKGNESPLRRVSDPTKR 349 Query: 322 ---VPYIFRDNQ-----WVGFDDVESFKTKVSYLKQKGLGGAMVWALDLDDFAGFSCNQG 373 + Y D Q WV +DD +S K +Y + K LGG ++ L DDF G C+ Sbjct: 350 FGGIAYRPVDGQITEGIWVSYDDPDSASNKAAYARVKNLGGVALFDLSYDDFRG-QCSGD 408 Query: 374 RYPLIQTLRQEL 385 +YP+++ ++ L Sbjct: 409 KYPILRAIKYRL 420 >3WD0-A nrPDB Length = 503 Score = 146 bits (368), Expect = 2e-35, Method: Compositional matrix adjust. Identities = 108/377 (28%), Positives = 175/377 (46%), Gaps = 68/377 (18%) Query: 51 CTHLIYAFAGMTNH-----QLSTTEWNDETLYQEFNGLKKMNPKLKTLLAIGGWNFGTQ- 104 TH+ ++F + ++ +T + + LK NP L+ + +IGGW + Sbjct: 48 LTHINFSFLDINSNLECAWDPATNDAKARDVVNRLTALKAHNPSLRIMFSIGGWYYSNDL 107 Query: 105 -----KFTDMVATANNRQTFVNSAIRFLRKYSFDGLDLDWEYPGSQGSPAVDKERFTTLV 159 + + V T R F S +R ++ Y FDG+D+DWEYP A + + F + Sbjct: 108 GVSHANYVNAVKTPAARTKFAQSCVRIMKDYGFDGVDIDWEYP-----QAAEVDGFIAAL 162 Query: 160 QDLANAFQQEAQTSGKERL--LLSAAVPAGQTYVDAGY-EVDKIAQNLDFVNLMAYDFHG 216 Q++ Q+ G++ L L+ A G ++ Y ++ +I LD++NLM YD G Sbjct: 163 QEIRTLLNQQTIADGRQALPYQLTIAGAGGAFFLSRYYSKLAQIVAPLDYINLMTYDLAG 222 Query: 217 SWEKVTGHNSPLYK-----------RQEESG-----------AAASLNVDAAVQQWL-QK 253 WEK+T H + L+ R+ G + SL VDAAVQQ L + Sbjct: 223 PWEKITNHQAALFGDAAGPTFYNALREANLGWSWEELTRAFPSPFSLTVDAAVQQHLMME 282 Query: 254 GTPASKLILGMPTYGRSFTLASSSDTRVGAPATGSGTPG--PFTKEGGMLAYYEVC---- 307 G P++K+++G+P YGR+F S + G + TPG P+ L + C Sbjct: 283 GVPSAKIVMGVPFYGRAFKGVSGGN---GGQYSSHSTPGEDPYPNADYWLVGCDECVRDK 339 Query: 308 -----SWKGATK--------QRIQDQ--KVPYIF--RDNQWVGFDDVESFKTKVSYLKQK 350 S++ + QR+ + K PY++ ++ +V +DD ESFK K Y+KQ+ Sbjct: 340 DPRIASYRQLEQMLQGNYGYQRLWNDKTKTPYLYHAQNGLFVTYDDAESFKYKAKYIKQQ 399 Query: 351 GLGGAMVWALDLDDFAG 367 LGG M W L D+ G Sbjct: 400 QLGGVMFWHLGQDNRNG 416 >5ZL9-A nrPDB Length = 618 Score = 127 bits (319), Expect = 9e-30, Method: Compositional matrix adjust. Identities = 100/327 (30%), Positives = 163/327 (49%), Gaps = 31/327 (9%) Query: 58 FAGMTNHQLSTTEWND--ETLYQEFNGLKKMNPKLKTLLAIGGWNFGTQKFTDMVATANN 115 FA + Q T W+D + + + LK+ +P LK L +IGGW F + Sbjct: 209 FAALQKAQKGVTAWDDPYKGNFGQLMALKQAHPDLKILPSIGGWTLSDPFF--FMGDKVK 266 Query: 116 RQTFVNSAIRFLRKYSF-DGLDLDWEYPGSQGS-PAV----DKERFTTLVQDLANAFQQE 169 R FV S FL+ + F DG+D+DWE+PG +G+ P + D E + L+++L Q Sbjct: 267 RDRFVGSVKEFLQTWKFFDGVDIDWEFPGGKGANPNLGSPQDGETYVLLMKELRAMLDQL 326 Query: 170 AQTSGKERLLLSAAVPAGQTYVDAGYEVDKIAQN-LDFVNLMAYDFHGSWE-KVTGH--- 224 + +G+ + L++A+ AG+ +D Y +AQN +D + LM+YDF+G+++ K GH Sbjct: 327 SVETGR-KYELTSAISAGKDKIDKFYSFVNVAQNSMDHIFLMSYDFYGAFDLKNLGHQTA 385 Query: 225 -NSPLYKRQEESGAAASLNVDAAVQQWLQKGTPASKLILGMPTYGRSFTLASSSDTRVGA 283 N+P +K A ++N V L +G K+++G YGR +T + + Sbjct: 386 LNAPAWKPDT---AYTTVN---GVNALLAQGVKPGKIVVGTAMYGRGWTGVNGYQNNI-- 437 Query: 284 PATGSGT-PGPFTKEGGMLAYYEVCS-WKGATKQRIQD--QKVPYIFR--DNQWVGFDDV 337 P TG+ T P T E G++ Y ++ + Q D + PY+F+ + FDD Sbjct: 438 PFTGTATGPVKGTWENGIVDYRQIAGQFMSGEWQYTYDATAEAPYVFKPSTGDLITFDDA 497 Query: 338 ESFKTKVSYLKQKGLGGAMVWALDLDD 364 S + K Y+ K LGG W +D D+ Sbjct: 498 RSVQAKGKYVLDKQLGGLFSWEIDADN 524 >5XWF-A nrPDB Length = 378 Score = 127 bits (318), Expect = 1e-29, Method: Compositional matrix adjust. Identities = 112/386 (29%), Positives = 178/386 (46%), Gaps = 76/386 (19%) Query: 23 KLVCYFTNWAQYRQGEARFLPKDLDPSLCTHLIYAFA---------GMTNHQLSTTEWND 73 KL Y +W LPK + H++YAFA G T+ QL Sbjct: 3 KLSAYVVDWD---------LPKSIAWDKLDHIVYAFAEPTKDGELSGFTDSQL------- 46 Query: 74 ETLYQEFNGLKKMNPKLKTLLAIGGWNFGTQKFTDMVATANNRQTFVNSAIRFLRKYSFD 133 +++ QE + K L++GGW G+ F+D++ ++++ FV++ + +++Y D Sbjct: 47 KSVVQEAHSRGK-----SISLSVGGWT-GSLYFSDLLKSSSSFDNFVSNLVDVVKEYDLD 100 Query: 134 GLDLDWEYPGSQGSPAVDK--ERFTTLVQDLANAFQQEAQTSGKERLLLSAAVPAG---- 187 GL+LDWEYP S A + E T L A +++ + + +L+ AVP Sbjct: 101 GLNLDWEYPNSPNGVACNSKDENDTANYLKLFKALREKLGS----KTILTTAVPTAPFND 156 Query: 188 -----QTYVDAGYEVDKIAQNLDFVNLMAYDFHGSWEKVTGHNSPLYKRQEESGAAASLN 242 T +D D A +D +MAYD +G +K G N+PLY + +G + Sbjct: 157 ENQQPSTKLD-----DNWASTVDAFYIMAYDVNGIRDKNAGANAPLYYSPKVTGVEPTSG 211 Query: 243 VDAAVQQWLQKGTPASKLILGMPTYGR-SFTLAS-SSDTRVGAPATGSG-TPGPFTKE-- 297 DA V+ W+ G PA +L+LG+P YGR S TL ++ T + P + S G T E Sbjct: 212 NDA-VKAWIAAGIPAEQLVLGVPFYGRVSKTLEPITASTGLYVPISQSSQIKGDSTDEKA 270 Query: 298 -----GGMLAYYEVCSWKGATKQRIQDQ------------KVPYI--FRDNQWVGFDDVE 338 + Y W+ ++ I K PY F ++ + FDD Sbjct: 271 ADPCPNAVATYSGQYIWRTIAQEGIARNSSGWVTYWDDISKTPYAYSFSGSKVLSFDDAA 330 Query: 339 SFKTKVSYLKQKGLGGAMVWALDLDD 364 S + KV Y K++GLGG M+W+L++DD Sbjct: 331 SLQDKVDYAKKQGLGGVMLWSLEMDD 356 >1KFW-A nrPDB Length = 435 Score = 125 bits (315), Expect = 3e-29, Method: Compositional matrix adjust. Identities = 116/409 (28%), Positives = 174/409 (42%), Gaps = 82/409 (20%) Query: 25 VCYFTNWAQYRQGEARFLPKDLDPSLC----THLIYAFAGMTNHQLSTTEWN-------- 72 V YF W Y + F K LD S TH+ Y+F + N L+ N Sbjct: 12 VGYFAQWGVYGRA---FQAKQLDVSGTAKNLTHINYSFGNINNQTLTCFMANKAQGTGPN 68 Query: 73 -----------------------------DETLYQEFNGLKKM---NPKLKTLLAIGGWN 100 D+ L FN LK++ NPKLK ++++GGW Sbjct: 69 GSDGAGDAWADFGMGYAADKSVSGKADTWDQPLAGSFNQLKQLKAKNPKLKVMISLGGWT 128 Query: 101 FGTQKFTDMVATANNRQTFVNSAIRFLRKYS----------------FDGLDLDWEYPGS 144 + ++ F+ AT +RQ V+S I K + FDG+D+DWE+PG+ Sbjct: 129 W-SKNFSKAAATEASRQKLVSSCIDLYIKGNLPNFEGRGGAGAAAGIFDGIDIDWEWPGT 187 Query: 145 QGSPA-------VDKERFTTLVQDLANAFQQEAQTSGKERLLLSAAVPAGQTYVDAGYEV 197 A D+ F L+ + T+ K + +LSA +PA +DAG Sbjct: 188 NSGLAGNGVDTVNDRANFKALLAEFRKQLDAYGSTNNK-KYVLSAFLPANPADIDAGGWD 246 Query: 198 DKIA-QNLDFVNLMAYDFHGSWE-KVTGHNSPLYKRQEESGA-AASLNVDAAVQQWLQKG 254 D ++LDF ++ YD HG+W +TGH + LY + A + + D AV+++L G Sbjct: 247 DPANFKSLDFGSIQGYDLHGAWNPTLTGHQANLYDDPADPRAPSKKFSADKAVKKYLAAG 306 Query: 255 TPASKLILGMPTYGRSFTLASSSDTRVGAPATGSGTPGPFTKEGGMLAYYEVCSWKGATK 314 +L LG+ YGR +T A + PAT G PG T E Y ++ + T Sbjct: 307 IDPKQLGLGLAAYGRGWTGAK--NVSPWGPAT-DGAPG--TYETANEDYDKLKTL--GTD 359 Query: 315 QRIQDQKVPYIFRDNQWVGFDDVESFKTKVSYLKQKGLGGAMVWALDLD 363 + + QW +D++ + K K Y+ KGLGG M W L D Sbjct: 360 HYDAATGSAWRYDGTQWWSYDNIATTKQKTDYIVSKGLGGGMWWELSGD 408 >4TXG-A nrPDB Length = 793 Score = 120 bits (302), Expect = 1e-27, Method: Compositional matrix adjust. Identities = 103/348 (29%), Positives = 159/348 (45%), Gaps = 71/348 (20%) Query: 19 GSAAKLVCYFTNWAQYRQGEARFLPKDLDPSLCTHLIYAFAGMT-NHQLSTTE------- 70 GS +++ YFT+W + G +L D+ S TH+ YAFA + +++LS E Sbjct: 151 GSRRRIIGYFTSWRTGKDGSPAYLASDIPWSKLTHINYAFAHVDGSNKLSVNETAPGNPA 210 Query: 71 ----W-------NDETL-YQ-EFNGL---KKMNPKLKTLLAIGGW------------NFG 102 W D +L Y+ FN L K+ P +KTL+++GGW Sbjct: 211 TDMSWPGVAGAEMDASLPYKGHFNLLTQYKRKYPGVKTLISVGGWAETGGYFDANGKRVA 270 Query: 103 TQKFTDMVATANNR------QTFVNSAIRFLRKYSFDGLDLDWEYPGSQ---GSP----- 148 + F M A+ F +SA+ FLRKY FDG+D+D+EYP S G+P Sbjct: 271 SGGFYSMTVNADGTVNQAGINAFSDSAVAFLRKYGFDGVDIDFEYPTSMNNAGNPLDWTF 330 Query: 149 -----AVDKERFTTLVQDLANAFQQEAQTSGKERLLLSAAVPAGQTYVDAGYEVDKIAQN 203 + + L+Q L + + A G+ ++AAVPA Y+ G E + + Sbjct: 331 SNARLGSLNKGYVALLQTLRDRLDRAAAQDGR-YYQITAAVPA-SGYLLRGMETFQGLKY 388 Query: 204 LDFVNLMAYDFHGSWEKVTGHNSPLYKRQEES-------------GAAASLNVDAAVQQW 250 LDFVN+M+YD HG+W + G N+ LY +++ G LN D A + Sbjct: 389 LDFVNVMSYDLHGAWNRFVGPNAALYDDGKDAELAFWNVYSTPQYGNIGYLNTDWAY-HY 447 Query: 251 LQKGTPASKLILGMPTYGRSFTLASSSDTRVGAPATGSGTPGPFTKEG 298 + G PAS++ +G+P Y R + S + + GS P T+ G Sbjct: 448 YRGGLPASRVNMGVPYYTRGWKNVSGGSNGLWGSSVGSNCPAGLTECG 495 >3ARQ-A nrPDB Length = 584 Score = 119 bits (298), Expect = 3e-27, Method: Compositional matrix adjust. Identities = 98/329 (29%), Positives = 143/329 (43%), Gaps = 46/329 (13%) Query: 77 YQEFNGLKKMNPKLKTLLAIGGWNFGTQKFTDMVATANNRQTFVNSAIRFLRKYSF-DGL 135 Y LK+ NP LK + +IGGW + F D V NR TFV S +FL+ + F DG+ Sbjct: 232 YAMLMALKQRNPDLKIIPSIGGWTL-SDPFYDFV-DKKNRDTFVASVKKFLKTWKFYDGV 289 Query: 136 DLDWEYPG------SQGSPAVDKERFTTLVQDLANAFQQEAQTSGKERLLLSAAVPAGQT 189 D+DWE+PG +G P D + L+++L + +G+ L SA Sbjct: 290 DIDWEFPGGGGAAADKGDPVNDGPAYIALMRELRVMLDELEAETGRTYELTSAIGVGYDK 349 Query: 190 YVDAGYEVDKIAQNLDFVNLMAYDFHGSWEKVTGHNSPLY---------------KRQEE 234 D Y Q +D++ M YDF+G W V GH + LY E Sbjct: 350 IEDVDYA--DAVQYMDYIFAMTYDFYGGWNNVPGHQTALYCGSFMRPGQCDGGGVDENGE 407 Query: 235 SGAAASLNVDAAVQQWLQKGTPASKLILGMPTYGRSF------TLASSSDTRVGAPATG- 287 + D +Q L +G PA+KL+LG YGR + TL +D G ATG Sbjct: 408 PYKGPAYTADNGIQLLLAQGVPANKLVLGTAMYGRGWEGVTPDTLTDPNDPMTGT-ATGK 466 Query: 288 -SGTPGPFTKEGGMLAYYEVCSWK-GATKQRIQ--------DQKVPYIFRDN--QWVGFD 335 G+ E G++ Y + S+ GA I + P+++ + + + FD Sbjct: 467 LKGSTAQGVWEDGVIDYKGIKSFMLGANNTGINGFEYGYDAQAEAPWVWNRSTGELITFD 526 Query: 336 DVESFKTKVSYLKQKGLGGAMVWALDLDD 364 D S K +Y K GL G W +D D+ Sbjct: 527 DHRSVLAKGNYAKSLGLAGLFSWEIDADN 555 >5GQB-A nrPDB Length = 553 Score = 115 bits (288), Expect = 4e-26, Method: Compositional matrix adjust. Identities = 92/323 (28%), Positives = 150/323 (46%), Gaps = 25/323 (7%) Query: 58 FAGMTNHQLSTTEWND--ETLYQEFNGLKKMNPKLKTLLAIGGWNFGTQKFTDMVATANN 115 +A + Q + WN+ + + + LK+ P LK L +IGGW F Sbjct: 225 WAALQKPQKGLSSWNEPYKGNFGQLMMLKQAKPDLKILPSIGGWTLADPFF--FFTDETK 282 Query: 116 RQTFVNSAIRFLRKYSF-DGLDLDWEYPGSQ------GSPAVDKERFTTLVQDLANAFQQ 168 R+ FV S FL+ + F DG+D+DWE+PG + GSP D E + L+++L + Sbjct: 283 RRRFVASVKDFLQTWKFFDGVDIDWEFPGGKGANPNLGSPK-DGEIYVLLMKELREMLNE 341 Query: 169 EAQTSGKERLLLSAAVPAGQTYVDAGYEVDKIAQNLDFVNLMAYDFHGSWEKVT-GHNSP 227 + +G+ + L++A+ AG + + + +D + M+YDF G+W T GH + Sbjct: 342 LSAETGR-KYELTSAISAGWDKIQV-VDYSAAQKYMDHIFFMSYDFKGAWSNDTLGHQAS 399 Query: 228 LYKRQEESGAAASLNVDAAVQQWLQKGTPASKLILGMPTYGRSFTLASSSDTRVGAPATG 287 LY + + D VQ L +G K+++G+ YGR +T + P TG Sbjct: 400 LY--APDWNEKETYTTDFGVQFLLAQGVSPKKIVVGVAMYGRGWT--GVHGYKDNNPFTG 455 Query: 288 SGT-PGPFTKEGGMLAYYEVCSWKGATKQRIQDQKV---PYIFR--DNQWVGFDDVESFK 341 + T P T + G++ Y E+ + K KV PY+FR + +DD S Sbjct: 456 NATGPVKGTWQDGVVDYREIATEIAQGKWEYHYDKVAQAPYVFRPATGDLITYDDARSTI 515 Query: 342 TKVSYLKQKGLGGAMVWALDLDD 364 K Y++ LGG W +D D+ Sbjct: 516 EKGKYVRANKLGGLFAWEIDADN 538 >3QOK-A nrPDB Length = 420 Score = 114 bits (284), Expect = 1e-25, Method: Compositional matrix adjust. Identities = 108/391 (27%), Positives = 162/391 (41%), Gaps = 66/391 (16%) Query: 25 VCYFTNWAQYRQGEARFLPKDLDPSLCTHLIYAFAGMTNHQLSTTE------------WN 72 V YF G + K LD THL Y+F + N + T W Sbjct: 29 VGYFNGGGDVTAGPGGDIDK-LDVRQITHLNYSFGLIYNDEKDETNAALKDPAHLHEIWL 87 Query: 73 DETL---YQEFNGLKKMNPKLKTLLAIGGWNFGTQKFTDMVATANNRQTFVNSAIRFLRK 129 + Q+ L+K NP LK LL++GGW G + F+ ATA +R F+ SA + +++ Sbjct: 88 SPKVQADLQKLPALRKQNPDLKVLLSVGGW--GARGFSGAAATAESRAVFIRSAQKIIQQ 145 Query: 130 YSFDGLDLDWEYP-----GSQGSPAVDKERFTTLVQDLANAFQQEAQTSGKERLLLSAAV 184 Y DG+DLDWE+P G S D++ FT L++ L A E+ L++ AV Sbjct: 146 YGLDGIDLDWEFPVNGAWGLVASQPADRDNFTALLKSLREAV--------GEQKLVTIAV 197 Query: 185 PAGQTYVDAGYEVDKIAQNLDFVNLMAYDF-HGSWEKVTGHNSPLYKRQE--ESGAAASL 241 A + +V +A L+++NLM YD +G+ NS LY AA Sbjct: 198 GANAESPKSWVDVKAVAPVLNYINLMTYDMAYGT----QYFNSNLYDSSHWPTVAAADKY 253 Query: 242 NVDAAVQQWLQKGTPASKLILGMPTYGR----------SFTLASSSDTRVGAPATGSGTP 291 + D V +L G S++ LG+ YGR +T A + + V P G Sbjct: 254 SADFVVNNYLAAGLKPSQMNLGIGFYGRVPKRAVEPGIDWTKADAQNNPVTQPYFGPQQI 313 Query: 292 GPFTKEGGMLAYYEVCSWKGATKQRIQD------------QKVPYIFRDNQ------WVG 333 F G L+ + + + D KVP++ + + Sbjct: 314 ALFASLGYDLSKDTYVKYNDIVGKLLNDPQKRFTEHWDDEAKVPWLSVQSAEGKPLFALS 373 Query: 334 FDDVESFKTKVSYLKQKGLGGAMVWALDLDD 364 +++ S K Y+K KGL GAM W DD Sbjct: 374 YENPRSVAIKADYIKAKGLAGAMFWEYGADD 404 >5Z7M-A nrPDB Length = 546 Score = 112 bits (279), Expect = 4e-25, Method: Compositional matrix adjust. Identities = 99/328 (30%), Positives = 160/328 (48%), Gaps = 35/328 (10%) Query: 58 FAGMTNHQLSTTEWND--ETLYQEFNGLKKMNPKLKTLLAIGGWNFGTQKFTDMVATANN 115 FA + Q T W+D + + + LK+ +P LK L +IGGW F + Sbjct: 209 FAALQKAQKGVTAWDDPYKGNFGQLMALKQAHPDLKILPSIGGWTLSDPFF--FMGDKVK 266 Query: 116 RQTFVNSAIRFLRKYSF-DGLDLDWEYPGSQGS-PAV----DKERFTTLVQDLANAFQQE 169 R FV S FL+ + F DG+D+ WE+PG +G+ P + D E + L+++L Q Sbjct: 267 RDRFVGSVKEFLQTWKFFDGVDIAWEFPGGKGANPNLGSPQDGETYVLLMKELRAMLDQL 326 Query: 170 AQTSGKERLLLSAAVPAGQTYVD-AGYEVDKIAQN-LDFVNLMAYDFHGSWE-KVTGH-- 224 + +G+ + L++A+ AG+ +D Y V AQN +D + LM+YDF+G+ + K GH Sbjct: 327 SVETGR-KYELTSAISAGKDMIDKVAYNV---AQNSMDHIFLMSYDFYGAADLKNLGHQT 382 Query: 225 --NSPLYKRQEESGAAASLNVDAAVQQWLQKGTPASKLILGMPTYGRSFTLASSSDTRVG 282 N+P +K A ++N V L +G K+++G YGR +T + + Sbjct: 383 ALNAPAWKPDT---AYTTVN---GVNALLAQGVKPGKIVVGTAMYGRGWTGVNGYQNNI- 435 Query: 283 APATGSGT-PGPFTKEGGMLAYYEVCS-WKGATKQRIQD--QKVPYIFR--DNQWVGFDD 336 P TG+ T P T E G++ Y ++ + Q D + PY+F+ + FDD Sbjct: 436 -PFTGTATGPVKGTWENGIVDYRQIAGQFMSGEWQYTYDATAEAPYVFKPSTGDLITFDD 494 Query: 337 VESFKTKVSYLKQKGLGGAMVWALDLDD 364 S + K Y+ K LGG +D D+ Sbjct: 495 ARSVQAKGKYVLDKQLGGLFSAMIDADN 522 >6F8N-A nrPDB Length = 414 Score = 112 bits (279), Expect = 4e-25, Method: Compositional matrix adjust. Identities = 109/390 (27%), Positives = 165/390 (42%), Gaps = 64/390 (16%) Query: 25 VCYFTNWAQYRQGEARFLPKDLDPSLCTHLIYAFAGMTNHQLSTTE---WNDETLYQEFN 81 V YF G + K LD + THL Y+F + N + T + L+Q + Sbjct: 14 VGYFNGGGDVTAGPGGDINK-LDVTQITHLNYSFGLIYNDEKQETNPALKDPSRLHQIYL 72 Query: 82 G------------LKKMNPKLKTLLAIGGWNFGTQKFTDMVATANNRQTFVNSAIRFLRK 129 L+K NP+LK LL++GGW G + F+ ATA +R F+ S + +++ Sbjct: 73 SPKVMADLQLLPVLRKQNPELKVLLSVGGW--GARGFSGAAATAESRAVFIRSVQQVIKQ 130 Query: 130 YSFDGLDLDWEYP-----GSQGSPAVDKERFTTLVQDLANAFQQEAQTSGKERLLLSAAV 184 Y DG+DLDW+YP G S D+ FT L+ +L A + + + + A V Sbjct: 131 YHLDGIDLDWQYPVNGAWGLVESQPADRANFTLLLAELHKALDKGKLLT----IAVGANV 186 Query: 185 PAGQTYVDAGYEVDKIAQNLDFVNLMAYDFHGSWEKVTGHNSPLYKRQE--ESGAAASLN 242 + Q +VD V IA LD++NLM YD + NS LY ++ AA + Sbjct: 187 KSPQEWVD----VKGIAPYLDYINLMTYDMAYGTQYF---NSNLYDSKQWPTVAAADRYS 239 Query: 243 VDAAVQQWLQKGTPASKLILGMPTYGR----------SFTLASSSDTRVGAPATGSGTPG 292 + V +L G ++L LG+ YGR + A ++ V P + Sbjct: 240 ANFVVDNYLAAGLKPAQLNLGIGFYGRVPKRATEPGIDWDKADAAKNPVTQPYFTARETA 299 Query: 293 PFTKEG------GMLAYYEVCSWKGATKQRI------QDQKVPYIFRDNQ------WVGF 334 F G Y ++ S QR D +VPY+ + + + Sbjct: 300 VFKAMGLDLTKDSYFKYNDIVSKLLNDPQRRFTAHWDSDAQVPYLTMKSAEGKPLFAISY 359 Query: 335 DDVESFKTKVSYLKQKGLGGAMVWALDLDD 364 ++ S K Y+K KGLGGAM W DD Sbjct: 360 ENPRSVALKADYIKSKGLGGAMFWEYGADD 389 >5DF0-A nrPDB Length = 545 Score = 103 bits (258), Expect = 1e-22, Method: Compositional matrix adjust. Identities = 93/328 (28%), Positives = 154/328 (46%), Gaps = 36/328 (10%) Query: 58 FAGMTNHQLSTTEWND--ETLYQEFNGLKKMNPKLKTLLAIGGWNFGTQKFTDMVATANN 115 +A + Q S + WN+ + + + K NP LK L +IGGW + + Sbjct: 222 WAAVQKPQKSVSAWNEPYKGNFGQLMAAKLANPHLKILPSIGGWTLSDPFY--FMHDVEK 279 Query: 116 RQTFVNSAIRFLRKYSF-DGLDLDWEYPGSQGS-PAV-DKER----FTTLVQDLANAFQQ 168 R FV+S FL+ + F DG+D+DWE+PG +G+ P++ D ER + L+++L Sbjct: 280 RNVFVDSVKEFLQVWKFFDGVDVDWEFPGGKGANPSLGDAERDAKTYILLLEELRAMLDD 339 Query: 169 EAQTSGKERLLLSAAVPAGQTYVDAGYEVDKIA--------QNLDFVNLMAYDFHGSWEK 220 +G+ L SA + AGY DKIA ++L + LM+YDF G+W Sbjct: 340 LEAQTGRVYELTSA--------ISAGY--DKIAVVNYAEAQKSLGKIFLMSYDFKGAWSN 389 Query: 221 VT-GHNSPLYKRQEESGAAASLNVDAAVQQWLQKGTPASKLILGMPTYGRSFTLASSSDT 279 G+ + +Y S + + AV L++G +K+I+G+ YGR +T ++ Sbjct: 390 TDLGYQTTVYAPSWNSEELYTTHY--AVDALLKQGVDPNKIIVGVAMYGRGWTGVTNYTN 447 Query: 280 RVGAPATGSGTPGPFTKEGGMLAYYEV-CSWKGATKQRIQDQKVPYIFRDNQ--WVGFDD 336 TG+G P T E G++ Y ++ + Y+F ++ + FD Sbjct: 448 DNYFSGTGNG-PVSGTWEDGVVDYRQIQKDLNNYVYTFDSAAQASYVFDKSKGDLISFDS 506 Query: 337 VESFKTKVSYLKQKGLGGAMVWALDLDD 364 V+S KV Y+ + LGG W +D D+ Sbjct: 507 VDSVLGKVKYVDRNKLGGLFAWEIDADN 534 >4W5U-B nrPDB Length = 408 Score = 88.6 bits (218), Expect = 6e-18, Method: Compositional matrix adjust. Identities = 104/401 (25%), Positives = 164/401 (40%), Gaps = 79/401 (19%) Query: 27 YFTNWAQYRQGEARFLPKDLDPS----LCTHLIYAFAGMTNHQLSTTE------------ 70 YFT W Y + F K+LD S TH+ YAF +T + + + Sbjct: 46 YFTEWGTYDR---NFNVKNLDTSGTAAKITHINYAFGNVTGGKCAIGDSYADYDKAFTAD 102 Query: 71 ---------WNDETLYQEFNGLKKMN---PKLKTLLAIGGWNFGTQKFTDMVATANNRQT 118 W D+ L FN L+++ P +K L + GGW + + F D A + Q Sbjct: 103 QSVSGQADTW-DQPLRGNFNQLRQLKAKYPHIKVLWSFGGWTW-SGGFADA---AKDPQG 157 Query: 119 FVNSAIRFLRK----YSFDGLDLDWEYPGSQG--SPAVDKERFTTLVQDLANAFQQEAQT 172 F S + FDG+D+DWEYP + G + + F L+ L + F E T Sbjct: 158 FAQSCYNLVHDPRWDGVFDGIDIDWEYPNACGLTCDSSGPDAFRNLMAALRSTFGDELVT 217 Query: 173 SGKERLLLSAAVPAGQTYVDAGYEVDKIAQNLDFVNLMAYDFHGSWEKV--TGHNSPL-- 228 + + + P G+ + AQ +D+ N+M YDF G+W+ T +SPL Sbjct: 218 AA----VTADGTPGGKIEAT---DYAGAAQYVDWYNVMTYDFFGAWDAQGPTAPHSPLTS 270 Query: 229 YKRQEESGAAASLNVDAAVQQWLQKGTPASKLILGMPTYGRSFTLASSSDTRVGAPATGS 288 Y + G ++ A+ + +G PA KL+LG+ YGR +T + AP + Sbjct: 271 YDGIPKQGFTSA----DAIAAFKAQGVPADKLLLGIGFYGRGWTGVTQD-----APGGTA 321 Query: 289 GTPGPFTKEGGMLAY---YEVCSWKGATKQRIQDQKVPYIFRDNQWVGFDDVESFKTKVS 345 P T E G+ Y C G Y + +D ++ +K++ Sbjct: 322 TGPAAGTWEQGIEDYKVLKNTCPVTGTVA------GTAYAHCGSNLWSYDTPDTIASKMA 375 Query: 346 YLKQKGLGGAMVWALDLDDFAGFSCNQGRYPLIQTLRQELS 386 + +GL GA W DF+G + + LI L L+ Sbjct: 376 WANDQGLRGAFAW-----DFSGDTADG---ELIAALSNGLA 408 >4DWS-C nrPDB Length = 546 Score = 87.0 bits (214), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 85/311 (27%), Positives = 135/311 (43%), Gaps = 25/311 (8%) Query: 86 MNPKLKTLLAIGGWNFGTQKFTDMVATANNRQTFVNSAIRFLRKYS-FDGLDLDWEYPGS 144 M KL +IGGW+ + F+ + + R+ FV S + F ++ F +D+DWEYPG Sbjct: 208 MGHKLDLAFSIGGWSL-SSYFSALAENPDERRVFVASVVDFFVRFPMFSCVDIDWEYPGG 266 Query: 145 QG-----SPAVDKERFTTLVQDLANAFQQEAQTSGKERLLLSAAVPAGQTYVDAGYEVDK 199 G S D E + L+++L +A S ++ +S A + + Sbjct: 267 GGDEGNISSDKDGENYVLLIKELRSALDSRFGYSNRKE--ISIACSGVKAKLKKSNIDQL 324 Query: 200 IAQNLDFVNLMAYDFHGS-WEKVTGHNSPLYKRQEESGAAA-SLNVDAAVQQWLQK-GTP 256 +A LD + LM+YDF G+ W GH++ LY ++ L+ +AA+ + G P Sbjct: 325 VANGLDNIYLMSYDFFGTIWADYIGHHTNLYSPKDPGEQELFDLSAEAAIDYLHNELGIP 384 Query: 257 ASKLILGMPTYGRSFT---LASSSDTRVGAPATGS---GTPGPF-TKEGGMLAYYEVCSW 309 K+ LG YGRS L + T+ G PA G+ G P F + M A + + Sbjct: 385 MEKIHLGYANYGRSAVGGDLTTRQYTKNG-PALGTMENGAPEFFDIVKNYMDAEHSLSMG 443 Query: 310 K-GATKQRIQDQKVPYIFRD--NQWVGFDDVESFKTKVSYLKQKGLGGAMVWALDLDDFA 366 K G + ++F + ++ D + K K Y + LGG W+ D D Sbjct: 444 KNGFVLMTDTNADADFLFSEAKGHFISLDTPRTVKQKGEYAAKNKLGGVFSWSGDQD--C 501 Query: 367 GFSCNQGRYPL 377 G N R L Sbjct: 502 GLLANAAREGL 512 >6OGD-C nrPDB Length = 633 Score = 87.0 bits (214), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 85/312 (27%), Positives = 138/312 (44%), Gaps = 27/312 (8%) Query: 86 MNPKLKTLLAIGGWNFGTQKFTDMVATANNRQTFVNSAIRFLRKYS-FDGLDLDWEYPGS 144 M KL +IGGW+ + F+ + + R+ FV S + F ++ F +D+DWEYPG Sbjct: 295 MGHKLDLAFSIGGWSL-SSYFSALAENPDERRVFVASVVDFFVRFPMFSCVDIDWEYPGG 353 Query: 145 QG-----SPAVDKERFTTLVQDLANAFQQEAQTSGKERLLLSAAVPAGQTYVDAGYEVDK 199 G S D E + L+++L +A S ++ + ++ +G +D+ Sbjct: 354 GGDEGNISSDKDGENYVLLIKELRSALDSRFGYSNRKEISIAC---SGVKAKLKKSNIDQ 410 Query: 200 IAQN-LDFVNLMAYDFHGS-WEKVTGHNSPLYKRQEESGAAA-SLNVDAAVQQWLQK-GT 255 + N LD + LM+YDF G+ W GH++ LY ++ L+ +AA+ + G Sbjct: 411 LVANGLDNIYLMSYDFFGTIWADYIGHHTNLYSPKDPGEQELFDLSAEAAIDYLHNELGI 470 Query: 256 PASKLILGMPTYGRSFT---LASSSDTRVGAPATGS---GTPGPF-TKEGGMLAYYEVCS 308 P K+ LG YGRS L + T+ G PA G+ G P F + M A + + Sbjct: 471 PMEKIHLGYANYGRSAVGGDLTTRQYTKNG-PALGTMENGAPEFFDIVKNYMDAEHSLSM 529 Query: 309 WK-GATKQRIQDQKVPYIFRD--NQWVGFDDVESFKTKVSYLKQKGLGGAMVWALDLDDF 365 K G + ++F + ++ D + K K Y + LGG W+ D D Sbjct: 530 GKNGFVLMTDTNADADFLFSEAKGHFISLDTPRTVKQKGEYAAKNKLGGVFSWSGDQD-- 587 Query: 366 AGFSCNQGRYPL 377 G N R L Sbjct: 588 CGLLANAAREGL 599 >4A5Q-A nrPDB Length = 546 Score = 80.9 bits (198), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 112/489 (22%), Positives = 195/489 (39%), Gaps = 126/489 (25%) Query: 24 LVCYFTNWAQYRQGEARFLPKDL----------------DPSLCTHLIYAFAGMT----- 62 ++CYFT+W+QY + R + K++ D LIY+F G+ Sbjct: 74 VLCYFTDWSQY---DPRIINKEIRDTGGRSADILRLNTPDGRPFKRLIYSFGGLIGDKKY 130 Query: 63 -----------------------NHQLST-----------------TEWN----DETLYQ 78 NH+ T T+W +E Q Sbjct: 131 SADGNASIAVRLGVATDPDDAIANHKGKTIPVDPDGAVLASINCGFTKWEAGDANERYNQ 190 Query: 79 E--------FNGLKKMNPKLKTLLAIGGWNFGTQKFTDMVATANNRQTFVNSAIRFLRKY 130 E F L + + +L+ L+IGGW+ + F+++ R FV F +++ Sbjct: 191 EKAKGLLGGFRLLHEADKELEFSLSIGGWSM-SGLFSEIAKDEILRTNFVEGIKDFFQRF 249 Query: 131 -SFDGLDLDWEYPGSQG-----SPAVDKERFTTLVQDLANAFQQEAQTSGKERLLLSAAV 184 F LD+DWEYPGS G SP D F L+Q + +A + + G +S A Sbjct: 250 PMFSHLDIDWEYPGSIGAGNPNSPD-DGANFAILIQQITDA--KISNLKG-----ISIAS 301 Query: 185 PAGQTYVDAGYEVDKIAQNLDFVNLMAYDFHGSWEKVTGHNSPLYKRQEESGAAASLNVD 244 A +DA + + +NLM YDF + H++ +Y+ + S + ++D Sbjct: 302 SADPAKIDAANIPALMDAGVTGINLMTYDFFTLGDGKLSHHTNIYR--DPSDVYSKYSID 359 Query: 245 AAVQQWL-QKGTPASKLILGMPTYGRSFTLASSSDTRVGAPATGSGTPGPFTKEGGMLAY 303 AV + +K + +G Y R+ A ++ P+ G +T L Sbjct: 360 DAVTHLIDEKKVDPKAIFIGYAGYTRN---AKNATITTSIPSE-EALKGTYTDANQTLGS 415 Query: 304 YE---------VCSW----KGATK---QRIQDQ--KVPYIFRD--NQWVGFDDVESFKTK 343 +E +C + KG + + + D+ K Y++ + ++ D S + K Sbjct: 416 FEYSVLEWTDIICHYMDFEKGEGRNGYKLVHDKVAKADYLYSEATKVFISLDTPRSVRDK 475 Query: 344 VSYLKQKGLGGAMVWALDLDDFAGFSCNQGRYPLIQTLRQ---ELSLPYLPSGTPELEVP 400 Y+K KGLGG +W+ D D+ G N L + ++ +++ YL S + E+P Sbjct: 476 GRYVKDKGLGGLFIWSGDQDN--GILTNAAHEGLKRRIKNKVIDMTPFYLDS---DEELP 530 Query: 401 KPGQPSEPE 409 +P+EP+ Sbjct: 531 TYTEPAEPQ 539 >4Q6T-A nrPDB Length = 351 Score = 58.9 bits (141), Expect = 4e-09, Method: Compositional matrix adjust. Identities = 59/261 (22%), Positives = 111/261 (42%), Gaps = 43/261 (16%) Query: 120 VNSAIRFLRKYSFDGLDLDWEYPGSQGSPAVDKERFTTLVQDLANAFQQEAQTSGKERLL 179 V ++ ++ F G++LD+E + ++ F V+ L NA + ++L+ Sbjct: 102 VKQLVKLAKEGGFAGINLDFEKVEPR-----NRAAFCAFVKTLGNALH-----ASNKKLI 151 Query: 180 LSAAVPAGQTYVD--AGYEVDKIAQNLDFVNLMAYDFHG-SWEKVTGHNSPLYKRQEESG 236 +S T + GY+ + +D+ +M YD G W HN + G Sbjct: 152 ISIPPKLSDTEPEYLQGYDYKALGAAVDYFQVMTYDQVGPGWSSGGFHN------EAWPG 205 Query: 237 AAASLNVDAAVQQWLQKGTPASKLILGMPTYGRSFTLASSSD---------TRVGAPATG 287 + + A+ + PASK++ G+PTYG+ +++ + A Sbjct: 206 PESGFDWQQALLSYAVSRVPASKVLAGLPTYGQDYSIGNRVHWSAYQEIIAEHRAAIHRD 265 Query: 288 SGTPGPFTKEGGMLAYYEVCSWKGATKQRIQDQKVPYIFRDNQWVGFDDVESFKTKVSYL 347 + + P+ G + ++ + W T +R Q P ++ +DD S KTK + + Sbjct: 266 AASATPYATWGPVKSFVDGVEW---TPERAQ----PVLW-------YDDAASIKTKTALV 311 Query: 348 KQKGLGGAMVWALDLDDFAGF 368 + GLGG VWA+ ++ AGF Sbjct: 312 TRLGLGGTSVWAMGYEN-AGF 331 >4WIW-A nrPDB Length = 349 Score = 55.8 bits (133), Expect = 4e-08, Method: Compositional matrix adjust. Identities = 68/283 (24%), Positives = 121/283 (42%), Gaps = 46/283 (16%) Query: 116 RQTFVNSAIRFLRKYSFDGLDLDWEYPGSQGSPAVDKERFTTLVQDLANAFQQ--EAQTS 173 R+ + + L+ + DG+ +D+E P G K+ + + DL AF + ++ Sbjct: 97 REKLIGEIVVLLKNTNADGVVIDFETPLDYGDV---KDPYDGVRNDLT-AFMESLHSELQ 152 Query: 174 GKERLLLSAAVP---AGQTYVDAGYEVDKIAQNLDFVNLMAYDFHGSWEKVTGHNSPLYK 230 +L++ A +P + Q ++DA Y+ + ++ +D++++M YD H Sbjct: 153 SMNKLVVMAVMPRMSSSQYWLDA-YDYEALSHAVDYLHVMTYDHH--------------Y 197 Query: 231 RQEESGAAASLNVDAAVQQWLQ-KGTPASKLILGMPTYGRSFTLASSSDTRVGAPATGSG 289 R G A V ++Q +G SK+++G+P YGR + + G P S Sbjct: 198 RTSAPGPIAPYPWIKQVLTYIQGQGVDMSKVLMGIPYYGRDWVVDGKDAN--GNPTYNST 255 Query: 290 TPGPFTKE-------GGMLAY--YEVCSWKGATKQRIQDQKVPYIFRDNQWVGFDDVESF 340 G ++K G + Y Y G + D+K V FDD S+ Sbjct: 256 AFG-YSKALELADSYGATITYSKYNDADPVGTPTFKYTDEK-----GVEHTVFFDDYTSW 309 Query: 341 KTKVSYLKQKGLGGAMVWALDLDDFAGFSCNQGRYPLI-QTLR 382 K+S + + GL G WA+ D + +G +PL+ Q LR Sbjct: 310 NAKLSIINEFGLAGVGPWAMGWVD---ENTAEGLFPLLNQHLR 349 >3CZ8-A nrPDB Length = 319 Score = 42.4 bits (98), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 41/190 (21%), Positives = 78/190 (41%), Gaps = 34/190 (17%) Query: 84 KKMNPKLKTLLAIGGWNFGTQKFTDMVATANNRQTFVNSAIRFLRKYSFDGLDLDWEYPG 143 +++ P L T+ + F T+ ++ R VN+ + + G+ +D+E Sbjct: 65 RRVTP-LATITNLTSGGFSTEIVHQVLNNPTARTNLVNNIYDLVSTRGYGGVTIDFE--- 120 Query: 144 SQGSPAVDKERFTTLVQDLANAFQQEAQTSGKERLLLSAAVPAGQTYVD-----AGYEVD 198 A D++ FT ++ L + Q +L+ AVPA + D GY+ Sbjct: 121 --QVSAADRDLFTGFLRQLRDRLQAGG-------YVLTIAVPAKTS--DNIPWLRGYDYG 169 Query: 199 KIAQNLDFVNLMAYDFHGSWEKVTGHNSPLYKRQEESGAAASLNVDAAVQQWLQKGTPAS 258 I ++++ +MAYD+H + E G A + ++ P+ Sbjct: 170 GIGAVVNYMFIMAYDWHHA--------------GSEPGPVAPITEIRRTIEFTIAQVPSR 215 Query: 259 KLILGMPTYG 268 K+I+G+P YG Sbjct: 216 KIIIGVPLYG 225 >4S3K-A nrPDB Length = 436 Score = 38.1 bits (87), Expect = 0.008, Method: Compositional matrix adjust. Identities = 63/279 (22%), Positives = 106/279 (37%), Gaps = 54/279 (19%) Query: 100 NFGTQKFTDMVATA--NNRQ---TFVNSAIRFLRKYSFDGLDLDWEYPGSQGSPAVDKER 154 N F+D V A NN+ T +N+ ++ ++ +F + D+E+ PA DKE Sbjct: 176 NIENGAFSDEVGRAILNNKDVQDTLLNNIVKTAKEQNFRDIHFDFEFL----RPA-DKEA 230 Query: 155 FTTLVQDLANAFQQEAQTSGKERLLLSAAVPAGQTYVDAG-----YEVDKIAQNLDFVNL 209 + +Q Q E +LL+S A+ + G ++ I + +FV Sbjct: 231 YIAFLQKAKKRLQDE-------QLLMSVALAPKTSRDQKGKWYEAHDYKAIGEIANFVVP 283 Query: 210 MAYDFHGSWEKVTGHNSPLYKRQEESGAAASLNVDAAVQQWLQKGTPASKLILGMPTYGR 269 M Y+ W G P+ A + + V ++ P+SK+I+G YG Sbjct: 284 MTYE----WGYSGG--PPM--------AVSPIGPVRDVLEYAVSEIPSSKIIMGQNLYGY 329 Query: 270 SFTLASSSDTRVGAPATGSGTPGPFTKEGGMLAYYEVCSWKGATKQRIQDQKVPYI-FRD 328 +TL G + K E+ + Q + P+ ++D Sbjct: 330 DWTLPYKPG-------------GEYAKAISPQRAIELAARYKVAIQYDNKAQAPFFRYKD 376 Query: 329 NQW----VGFDDVESFKTKVSYLKQKGLGGAMVWALDLD 363 Q V F+D S + K +K+ L G W L LD Sbjct: 377 EQQRTHEVWFEDARSIQAKFDLIKELKLRGMAYWKLGLD 415 >3N18-A nrPDB Length = 333 Score = 38.1 bits (87), Expect = 0.009, Method: Compositional matrix adjust. Identities = 52/182 (28%), Positives = 74/182 (40%), Gaps = 27/182 (14%) Query: 24 LVCYFTNWAQYRQGEARFLPKDLDPSLCTHLIYAFAGMTNHQLSTTEWN-----DETLYQ 78 LV Y W + G KD+ P +I G T ST E++ D Sbjct: 9 LVGY---WHNFDNGTGIIKLKDVSPKW--DVINVSFGETGGDRSTVEFSPVYGTDADFKS 63 Query: 79 EFNGLKKMNPKLKTLLAIGGWNFGTQKFTDMVATANNRQTFVNSAIRFLRKYSFDGLDLD 138 + + LK K+ +L+IGG N G D A + F+NS + KY FDG+D+D Sbjct: 64 DISYLKSKGKKV--VLSIGGQN-GVVLLPDNAA----KDRFINSIQSLIDKYGFDGIDID 116 Query: 139 WEYPGS----QGSPAVDKERFTTLVQDLANAFQQEAQTSGKERLLLSAAVPAGQTYVDAG 194 GS G+ K T + +L +A + + G + LL A A YV G Sbjct: 117 L---GSGIYLNGNDTNFKNPTTPQIVNLISAIRTISDHYGPDFLLSMAPETA---YVQGG 170 Query: 195 YE 196 Y Sbjct: 171 YS 172 >5JH8-A nrPDB Length = 317 Score = 37.4 bits (85), Expect = 0.014, Method: Compositional matrix adjust. Identities = 61/286 (21%), Positives = 114/286 (39%), Gaps = 70/286 (24%) Query: 97 GGWNFGTQKFTDMVATANNRQTFVNSAIRFLRKYSFDGLDLDWEYPGSQGSPAVDKERFT 156 G W + V+T+ Q N ++F + F G+++D+E +QG D+ F+ Sbjct: 74 GNW---SADIAHAVSTSAQSQAVAN-LVKFAQDKRFSGINVDFE-AVAQG----DRNNFS 124 Query: 157 TLVQDLANAFQQEAQTSGKERLLLSAAVPAGQTY-----VDAGYEVDKIAQNLDFVNLMA 211 +Q L A + L L +VPA + GY++ + D++ +M+ Sbjct: 125 HFIQVLGRALHAKG-------LKLIVSVPAFSAKDENHPANYGYDLRALGAAADYLQIMS 177 Query: 212 YDFHGSWEKVTGHNSPLYKRQEESGAA-ASLNVDAAVQQWLQKGTPASKLILGMPTYGRS 270 YD E + P + +G+ ++D AV++ PA+K++ G+P YG Sbjct: 178 YD-----EAI-----PAWDPGPVAGSDWMEDDLDYAVER-----VPAAKILNGIPAYGYD 222 Query: 271 FTLASSSDTRVGAPATGSGTPGPFTKEGGMLAYYE----VCSWKGATKQRIQDQKVPYIF 326 + PG +GGML + + + + + + + + Sbjct: 223 WK-----------------RPG----DGGMLYWKDTQALIARYGAQPRYDAGTHSLTFNY 261 Query: 327 ------RDNQWVGFDDVESFKTKVSYLKQKGLGGAMVWALDLDDFA 366 R W ++ S K S + GLGG ++AL ++D A Sbjct: 262 GAADGSRHTVWT--ENARSVALKASLVNAYGLGGTSLYALGMEDDA 305 >3CO4-A nrPDB Length = 312 Score = 37.4 bits (85), Expect = 0.014, Method: Compositional matrix adjust. Identities = 43/186 (23%), Positives = 83/186 (44%), Gaps = 32/186 (17%) Query: 105 KFTDMVATANNRQTFVNSAIRFLRKYSFDGLDLDWEYPGSQGSPAVDKERFTTLVQDLAN 164 +FT + R+ + I F ++Y DG D+D+E + DK + LV Sbjct: 79 EFTTAINDPKARKELIQQIIAFTKEYKLDGFDIDYEEYDNW-----DKNFPSLLV----- 128 Query: 165 AFQQEAQTSGKERLLLSAAVPAGQTYVDAGYEVDKIAQNLDFVNLMAYDFHGSWEKVTGH 224 F + + ++ +L++ AV + +++ G E + Q D++NLM+YD +K H Sbjct: 129 -FARGLYLAKEKNMLMTCAVNS--RWLNYGTEWE---QYFDYINLMSYDRGAFTDKPVQH 182 Query: 225 NSPLYKRQEESGAAASLNVDAAVQQWLQKGTPA-SKLILGMPTYGRSF--TLASSSDTRV 281 A+ + ++ W ++ + SK++ G+P YG S+ +L + D Sbjct: 183 -------------ASYDDFVKDLKYWNEQCRASKSKIVGGLPFYGYSWEESLQGAVDDVR 229 Query: 282 GAPATG 287 G +G Sbjct: 230 GIRYSG 235 >3SIM-A nrPDB Length = 275 Score = 37.4 bits (85), Expect = 0.015, Method: Compositional matrix adjust. Identities = 32/147 (21%), Positives = 64/147 (43%), Gaps = 10/147 (6%) Query: 79 EFNGLKKMNPKLKTLLAIGGWNFGTQKFTDMVATANN-RQTFVNSAIRFLRKYSFDGLDL 137 + + +K +P ++ +++GG + G+ A+ ++ V S R +++Y+ DG+D+ Sbjct: 65 QISAIKSSHPNVRVAVSLGGASVGSNTVQFQAASVDSWVSNAVTSLTRIIQRYNLDGIDI 124 Query: 138 DWEYPGSQGSPAVDKERFTTLVQDLANAFQQEAQTSGKERLLLSAAVPAGQTYVDAGYEV 197 D+E+ + DK F + L ++ +G + P+ Y A + Sbjct: 125 DYEHFQN-----TDKNTFAECIGRLITTLKK----NGVISFASISPFPSVDEYYLALFNE 175 Query: 198 DKIAQNLDFVNLMAYDFHGSWEKVTGH 224 K A N AYD S +K G+ Sbjct: 176 YKNAINHINYQFKAYDSSTSVDKFLGY 202 >3IAN-A nrPDB Length = 321 Score = 36.6 bits (83), Expect = 0.021, Method: Compositional matrix adjust. Identities = 44/194 (22%), Positives = 79/194 (40%), Gaps = 28/194 (14%) Query: 83 LKKMNPKLKT-LLAIGGWNFGTQKFTDMVATANNRQTFVNSAIRFLRKYSFDGLDLDWEY 141 + K+N + K+ L+A+GG + + + FVN IR + Y FDGLD+D E Sbjct: 72 ISKLNAEGKSVLIALGGAD------AHIELKKSQESDFVNEIIRLVDTYGFDGLDIDLE- 124 Query: 142 PGSQGSPAVDKERFTTLVQDLANAFQQEAQTSGKERLL-LSAAVPAGQTYVDAGYEVDKI 200 A++ T++ + + GK ++ ++ P + ++ + Sbjct: 125 -----QAAIEAADNQTVIPSALKKVKDHYRKDGKNFMITMAPEFPYLTSSGKYAPYINNL 179 Query: 201 AQNLDFVNLMAYDFHGS--WEKVTGHNSPLYKRQEESGAAASLNVDAAVQQWLQKGT--- 255 DF+N Y+ G W+ S L +S + + Q L GT Sbjct: 180 DSYYDFINPQYYNQGGDGFWD------SDLNMWISQSNDEKKEDFLYGLTQRLVTGTDGF 233 Query: 256 ---PASKLILGMPT 266 PASK ++G+P+ Sbjct: 234 IKIPASKFVIGLPS 247 >3EBV-A nrPDB Length = 302 Score = 36.6 bits (83), Expect = 0.022, Method: Compositional matrix adjust. Identities = 17/50 (34%), Positives = 29/50 (58%), Gaps = 5/50 (10%) Query: 91 KTLLAIGGWNFGTQKFTDMVATANNRQTFVNSAIRFLRKYSFDGLDLDWE 140 K ++++GG +K T V ++ + F NS +R+Y FDG+D+D E Sbjct: 77 KVIISVGG-----EKGTVSVNSSASATNFANSVYSVMREYGFDGVDIDLE 121 >4TX8-A nrPDB Length = 439 Score = 36.6 bits (83), Expect = 0.023, Method: Compositional matrix adjust. Identities = 20/50 (40%), Positives = 27/50 (54%), Gaps = 5/50 (10%) Query: 91 KTLLAIGGWNFGTQKFTDMVATANNRQTFVNSAIRFLRKYSFDGLDLDWE 140 K +L++GG Q + + A Q FVNS L +Y FDG+DLD E Sbjct: 176 KVVLSLGG-----QNGSVTLNNATQVQNFVNSLYGILTQYGFDGIDLDLE 220 >4Z4A-A nrPDB Length = 121 Score = 35.8 bits (81), Expect = 0.041, Method: Compositional matrix adjust. Identities = 17/57 (29%), Positives = 31/57 (54%), Gaps = 7/57 (12%) Query: 416 QDTFCQGKADGLYPNPRERSSFYSCA-------AGRLFQQSCPTGLVFSNSCKCCTW 465 + T C G D LYP+P+ + + C+ G + + CP+GL+++++ K C W Sbjct: 34 KTTKCLGPKDCLYPSPKTCNGYIQCSPADDSYLTGIIHEMPCPSGLLWNDNKKWCDW 90 >4NUY-A nrPDB Length = 899 Score = 35.8 bits (81), Expect = 0.044, Method: Compositional matrix adjust. Identities = 31/113 (27%), Positives = 50/113 (44%), Gaps = 27/113 (23%) Query: 126 FLRKYSFDGLDLDWEYPGSQGSPAVDKERFTTLVQDLANAFQQEAQTSG-----KERLLL 180 ++ KY+ DGLD+D E+ P VDK+ T V+ F++ + G K RL + Sbjct: 124 YVYKYNLDGLDVDVEH---DSIPKVDKKEDTAGVERSIQVFEEIGKLIGPKGVDKSRLFI 180 Query: 181 SAAVPAGQTYVDAGYEVDK---IAQNLDFVNLMAYDFHGS------WEKVTGH 224 +D+ Y DK I + ++NL+ +GS WE V+ Sbjct: 181 ----------MDSTYMADKNPLIERGAPYINLLLVQVYGSQGEKGGWEPVSNR 223 >2Y8V-A nrPDB Length = 290 Score = 34.7 bits (78), Expect = 0.087, Method: Compositional matrix adjust. Identities = 28/123 (22%), Positives = 49/123 (39%), Gaps = 7/123 (5%) Query: 23 KLVCYFTNWAQYRQGEARFLPKDLDPSLCTHLIYAFAGMTNHQLSTTEWNDETLYQEFNG 82 +++CY R LP + + TH+I A + T +D ++ +N Sbjct: 14 RVICYHQTLCPNRGDYVSVLPLVKNNTGVTHIIIAAFHLNEDPGHITLNDDPPDHEMYNP 73 Query: 83 LKKMNPKLK-----TLLAIGGWNFGTQKFTDMVATANNRQTFVNSAIRFLRKYSFDGLDL 137 L P LK + +GG G+ + D + + + +R++ DGLDL Sbjct: 74 LWAEVPVLKRSGVKVMGMLGGAAQGSYRCLD--GDQEKFERYYQPLLAMVRRHQLDGLDL 131 Query: 138 DWE 140 D E Sbjct: 132 DVE 134 >2QU8-A nrPDB Length = 228 Score = 32.0 bits (71), Expect = 0.58, Method: Compositional matrix adjust. Identities = 17/41 (41%), Positives = 23/41 (56%), Gaps = 2/41 (4%) Query: 74 ETLYQEFNGLKKMNPKLKTLLAIGGWNFGTQKFTDMVATAN 114 E LY F GL +NP KT++ G N G F ++V+ AN Sbjct: 15 ENLY--FQGLPSINPHKKTIILSGAPNVGKSSFMNIVSRAN 53 >4RL3-A nrPDB Length = 272 Score = 31.6 bits (70), Expect = 0.68, Method: Compositional matrix adjust. Identities = 24/116 (20%), Positives = 46/116 (39%), Gaps = 20/116 (17%) Query: 40 RFLPKDLDPSLCTHLIYAFA------GMTNHQLSTTEWNDETLY-QEFNGLKKMNPKLKT 92 +F ++ + H I AFA + + W + L +K + +K Sbjct: 16 QFTDVPINSGVTFHFILAFAIDYTSAAAATNGVFNIYWQNSVLTPAAVQAIKAQHSNVKV 75 Query: 93 LLAIGG-------WNFGTQKFTDMVATANNRQTFVNSAIRFLRKYSFDGLDLDWEY 141 ++++GG F + VA A V+S + +Y DG+D+D+E+ Sbjct: 76 MVSLGGDTISGSPVQFTATSVSSWVANA------VSSLTSLINQYHLDGIDIDYEH 125 >6BN0-A nrPDB Length = 79 Score = 31.2 bits (69), Expect = 0.89, Method: Composition-based stats. Identities = 19/62 (30%), Positives = 28/62 (45%), Gaps = 7/62 (11%) Query: 404 QPSEPEHGPSPGQDTFCQGKADGLYPNPRERSSFYSCAA------GRLFQQSCPTGLVFS 457 QP P P DT C G D LYPNP +++ C + + CP GL ++ Sbjct: 1 QPYNPCK-PQEVIDTKCMGPKDCLYPNPDSCTTYIQCVPLDEVGNAKPVVKPCPKGLQWN 59 Query: 458 NS 459 ++ Sbjct: 60 DN 61 >1FJ2-A nrPDB Length = 232 Score = 31.2 bits (69), Expect = 0.94, Method: Compositional matrix adjust. Identities = 18/64 (28%), Positives = 35/64 (54%), Gaps = 1/64 (1%) Query: 217 SWEKVTGHNSPLYKRQEESGAAASLNVDAAVQQWLQKGTPASKLILGMPTYGRSFTLASS 276 SW + G SP + E A+ N+ A + Q ++ G P++++ILG + G + +L ++ Sbjct: 73 SWFDIIGL-SPDSQEDESGIKQAAENIKALIDQEVKNGIPSNRIILGGFSQGGALSLYTA 131 Query: 277 SDTR 280 T+ Sbjct: 132 LTTQ 135 >5E1J-A nrPDB Length = 741 Score = 31.2 bits (69), Expect = 1.1, Method: Compositional matrix adjust. Identities = 44/175 (25%), Positives = 65/175 (37%), Gaps = 37/175 (21%) Query: 7 WAGFMVLLMIPWGSAAKLVCYFTNWAQYRQGEARFLPKDLDPSL--------CTHLIY-- 56 W +++L +L+ N +YR A F+ L PSL C IY Sbjct: 529 WIRYLLL-----ARMLRLIRLLMNVQRYRAFIATFIT--LIPSLMPYLGTIFCVLCIYCS 581 Query: 57 ----AFAGMTN---HQLSTTEW-NDETLYQEFNGLKKMNPKLKTLLAIGGWNFGTQKFTD 108 F G+ N +L TE D+ L FN L LL +G W + + D Sbjct: 582 IGVQVFGGLVNAGNKKLFETELAEDDYLLFNFNDYPNGMVTLFNLLVMGNWQVWMESYKD 641 Query: 109 MVATANNRQTFV-----------NSAIRFLRKYSFDGLDLDWEYPGSQGSPAVDK 152 + T + FV N + F+ + F LDL+ E QG + +K Sbjct: 642 LTGTWWSITYFVSFYVITILLLLNLVVAFVLEAFFTELDLE-EEEKCQGQDSQEK 695 >3BXW-B nrPDB Length = 393 Score = 31.2 bits (69), Expect = 1.1, Method: Compositional matrix adjust. Identities = 44/190 (23%), Positives = 77/190 (40%), Gaps = 37/190 (19%) Query: 106 FTDMVATANNRQTFVNSAIRFLRKYSFDGLDLD-WEYPGSQGSPAVDKERFTTLVQDLAN 164 F +++ + + + + ++ + FDG ++ W SQ + ++ LA Sbjct: 160 FRNVLDSEDEIEELSKTVVQVAKNQHFDGFVVEVWNQLLSQKRVGL-----IHMLTHLAE 214 Query: 165 AFQQEAQTSGKERLLLSAAVP------AGQTYVDAGYEVDKIAQNLDFVNLMAYDFHGSW 218 A Q RLL +P Q + E +++A LD +LM YD+ + Sbjct: 215 ALHQA-------RLLALLVIPPAITPGTDQLGMFTHKEFEQLAPVLDGFSLMTYDYSTAH 267 Query: 219 EKVTGHNSPLYKRQEESGAAASLNVDAAVQQWLQKGTPASKLILGMPTYGRSFTLASSSD 278 + G N+PL S A + V +W SK++LG+ YG + A+S D Sbjct: 268 Q--PGPNAPL------SWVRACVQVLDPKSKW------RSKILLGLNFYGMDY--ATSKD 311 Query: 279 TRVGAPATGS 288 R P G+ Sbjct: 312 AR--EPVVGA 319 >1CR6-A nrPDB Length = 554 Score = 30.8 bits (68), Expect = 1.2, Method: Compositional matrix adjust. Identities = 23/83 (27%), Positives = 33/83 (39%), Gaps = 7/83 (8%) Query: 143 GSQGSPAVDKERFTTLVQDLANAFQQEAQTSGKERLLLSAAVPAGQTYVDAGYEVDKIAQ 202 GS PA D T LV + A+A ++ + +G + VP V GY K Sbjct: 187 GSNLKPARDMGMVTILVHNTASALRELEKVTGTQFPEAPLPVPCNPNDVSHGYVTVKPGI 246 Query: 203 NLDFVNL-------MAYDFHGSW 218 L FV + + + F SW Sbjct: 247 RLHFVEMGSGPALCLCHGFPESW 269 >4S3J-A nrPDB Length = 433 Score = 29.6 bits (65), Expect = 2.8, Method: Compositional matrix adjust. Identities = 11/31 (35%), Positives = 20/31 (64%) Query: 332 VGFDDVESFKTKVSYLKQKGLGGAMVWALDL 362 V F+D S ++K + +K++G+GG W + L Sbjct: 382 VWFEDARSIQSKFNLMKEQGIGGISYWKIGL 412 >3SM3-A nrPDB Length = 235 Score = 29.3 bits (64), Expect = 3.4, Method: Compositional matrix adjust. Identities = 23/89 (25%), Positives = 38/89 (42%), Gaps = 18/89 (20%) Query: 218 WEKVTGHNSPLYKRQEESGAAASLNVDAAVQQWLQK-------GTPASKLILGMPTYGRS 270 WEKV+G N P +SL++ + +LQ+ G + K+ L + + G S Sbjct: 6 WEKVSGKNIP-----------SSLDLYPIIHNYLQEDDEILDIGCGSGKISLELASKGYS 54 Query: 271 FTLASSSDTRVGAPATGSGTPGPFTKEGG 299 T + + T + +PG K GG Sbjct: 55 VTGIDINSEAIRLAETAARSPGLNQKTGG 83 >1DQC-A nrPDB Length = 74 Score = 28.1 bits (61), Expect = 7.7, Method: Composition-based stats. Identities = 14/41 (34%), Positives = 19/41 (46%) Query: 425 DGLYPNPRERSSFYSCAAGRLFQQSCPTGLVFSNSCKCCTW 465 DG N SFY+C ++CP GL ++ K C W Sbjct: 15 DGPNVNLYSCCSFYNCHKCLARLENCPKGLHYNAYLKVCDW 55 >4DDQ-A nrPDB Length = 502 Score = 28.1 bits (61), Expect = 8.1, Method: Compositional matrix adjust. Identities = 18/67 (26%), Positives = 26/67 (38%) Query: 93 LLAIGGWNFGTQKFTDMVATANNRQTFVNSAIRFLRKYSFDGLDLDWEYPGSQGSPAVDK 152 +L G NFG+ A ++ LR + D +D Y GS+ P V Sbjct: 102 MLVDGHGNFGSVDGDSAAAMRYTEARMSKISMEILRDITKDTIDYQDNYDGSEREPVVMP 161 Query: 153 ERFTTLV 159 RF L+ Sbjct: 162 SRFPNLL 168 >6FTI-5 nrPDB Length = 705 Score = 28.1 bits (61), Expect = 9.5, Method: Compositional matrix adjust. Identities = 16/66 (24%), Positives = 25/66 (37%), Gaps = 2/66 (3%) Query: 209 LMAYDFHGSWEKVTGHNSPLYKRQEESGAAASLNVD--AAVQQWLQKGTPASKLILGMPT 266 L+ Y FH +W ++SP G + + D WL+ TP ++ Sbjct: 468 LITYTFHSTWVTSEAYSSPSIVLSARGGDGSRIIFDDFREAYYWLRHNTPEDAKVMSWWD 527 Query: 267 YGRSFT 272 YG T Sbjct: 528 YGYQIT 533 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 1WB0-A nrPDB 702 0.0 4WKA-A nrPDB 571 e-163 5WUS-A nrPDB 568 e-162 3RM8-A nrPDB 526 e-149 6G9C-A nrPDB 523 e-149 5XEP-A nrPDB 514 e-146 1HJW-A nrPDB 499 e-141 5WV8-A nrPDB 485 e-137 2QF8-A nrPDB 476 e-134 1E9L-A nrPDB 471 e-133 4P8U-A nrPDB 469 e-132 3W4R-A nrPDB 454 e-128 3WKZ-A nrPDB 429 e-120 5Y29-A nrPDB 422 e-118 5Y2C-A nrPDB 420 e-118 6BT9-A nrPDB 368 e-102 1ITX-A nrPDB 356 1e-98 5GZU-A nrPDB 341 5e-94 3AQU-A nrPDB 339 1e-93 3CHF-A nrPDB 334 6e-92 3G6L-A nrPDB 331 3e-91 4MNK-A nrPDB 331 3e-91 3ALF-A nrPDB 331 4e-91 6EPB-A nrPDB 330 7e-91 1LL6-A nrPDB 326 1e-89 5GQB-A nrPDB 317 5e-87 5ZL9-A nrPDB 313 1e-85 3QOK-A nrPDB 308 2e-84 6F8N-A nrPDB 308 4e-84 3ARQ-A nrPDB 301 4e-82 5DF0-A nrPDB 299 2e-81 4URI-A nrPDB 299 2e-81 5Z7M-A nrPDB 298 3e-81 1KFW-A nrPDB 290 1e-78 3WD0-A nrPDB 286 1e-77 1JNE-A nrPDB 285 4e-77 4A5Q-A nrPDB 266 1e-71 4W5U-B nrPDB 266 2e-71 4TXG-A nrPDB 264 6e-71 4DWS-C nrPDB 254 4e-68 6OGD-C nrPDB 253 1e-67 5XWF-A nrPDB 248 3e-66 4WIW-A nrPDB 169 3e-42 4Q6T-A nrPDB 154 8e-38 3CZ8-A nrPDB 147 1e-35 Sequences not found previously or not previously below threshold: 3CO4-A nrPDB 118 5e-27 4S3J-A nrPDB 104 8e-23 4S3K-A nrPDB 100 2e-21 5JH8-A nrPDB 97 1e-20 3BXW-B nrPDB 69 6e-12 3SIM-A nrPDB 56 3e-08 3EBV-A nrPDB 56 4e-08 3IAN-A nrPDB 55 8e-08 4Z4A-A nrPDB 55 9e-08 4TX8-A nrPDB 54 1e-07 4RL3-A nrPDB 53 3e-07 3N18-A nrPDB 52 4e-07 1NAR-A nrPDB 48 8e-06 4AXN-A nrPDB 47 2e-05 6BN0-A nrPDB 46 3e-05 4W5Z-A nrPDB 45 5e-05 2Y8V-A nrPDB 45 5e-05 1EDT-A nrPDB 45 5e-05 4MB4-A nrPDB 43 2e-04 4NUY-A nrPDB 42 4e-04 6MDV-A nrPDB 41 0.001 1F8Q-A nrPDB 39 0.004 4GUW-A nrPDB 38 0.009 2EBN-A nrPDB 37 0.018 6Q64-A nrPDB 36 0.028 1DQC-A nrPDB 36 0.045 2XVP-A nrPDB 32 0.54 5KEG-A nrPDB 32 0.59 2GSJ-A nrPDB 32 0.84 2WOQ-A nrPDB 31 0.92 1UZQ-A nrPDB 31 1.2 2MMY-A nrPDB 31 1.2 4TOQ-A nrPDB 30 1.5 6BWY-A nrPDB 30 2.4 3V4J-A nrPDB 30 2.4 6BUX-A nrPDB 30 2.4 1E5Q-A nrPDB 29 4.9 3UU2-A nrPDB 29 5.7 2VY0-A nrPDB 29 5.7 1KQY-A nrPDB 28 6.1 5WTL-A nrPDB 28 7.8 5LA1-A nrPDB 28 7.8 5G56-A nrPDB 28 8.6 3OIS-A nrPDB 28 8.8 1V5D-A nrPDB 28 9.4 >1WB0-A nrPDB Length = 445 Score = 702 bits (1811), Expect = 0.0, Method: Composition-based stats. Identities = 445/445 (100%), Positives = 445/445 (100%) Query: 22 AKLVCYFTNWAQYRQGEARFLPKDLDPSLCTHLIYAFAGMTNHQLSTTEWNDETLYQEFN 81 AKLVCYFTNWAQYRQGEARFLPKDLDPSLCTHLIYAFAGMTNHQLSTTEWNDETLYQEFN Sbjct: 1 AKLVCYFTNWAQYRQGEARFLPKDLDPSLCTHLIYAFAGMTNHQLSTTEWNDETLYQEFN 60 Query: 82 GLKKMNPKLKTLLAIGGWNFGTQKFTDMVATANNRQTFVNSAIRFLRKYSFDGLDLDWEY 141 GLKKMNPKLKTLLAIGGWNFGTQKFTDMVATANNRQTFVNSAIRFLRKYSFDGLDLDWEY Sbjct: 61 GLKKMNPKLKTLLAIGGWNFGTQKFTDMVATANNRQTFVNSAIRFLRKYSFDGLDLDWEY 120 Query: 142 PGSQGSPAVDKERFTTLVQDLANAFQQEAQTSGKERLLLSAAVPAGQTYVDAGYEVDKIA 201 PGSQGSPAVDKERFTTLVQDLANAFQQEAQTSGKERLLLSAAVPAGQTYVDAGYEVDKIA Sbjct: 121 PGSQGSPAVDKERFTTLVQDLANAFQQEAQTSGKERLLLSAAVPAGQTYVDAGYEVDKIA 180 Query: 202 QNLDFVNLMAYDFHGSWEKVTGHNSPLYKRQEESGAAASLNVDAAVQQWLQKGTPASKLI 261 QNLDFVNLMAYDFHGSWEKVTGHNSPLYKRQEESGAAASLNVDAAVQQWLQKGTPASKLI Sbjct: 181 QNLDFVNLMAYDFHGSWEKVTGHNSPLYKRQEESGAAASLNVDAAVQQWLQKGTPASKLI 240 Query: 262 LGMPTYGRSFTLASSSDTRVGAPATGSGTPGPFTKEGGMLAYYEVCSWKGATKQRIQDQK 321 LGMPTYGRSFTLASSSDTRVGAPATGSGTPGPFTKEGGMLAYYEVCSWKGATKQRIQDQK Sbjct: 241 LGMPTYGRSFTLASSSDTRVGAPATGSGTPGPFTKEGGMLAYYEVCSWKGATKQRIQDQK 300 Query: 322 VPYIFRDNQWVGFDDVESFKTKVSYLKQKGLGGAMVWALDLDDFAGFSCNQGRYPLIQTL 381 VPYIFRDNQWVGFDDVESFKTKVSYLKQKGLGGAMVWALDLDDFAGFSCNQGRYPLIQTL Sbjct: 301 VPYIFRDNQWVGFDDVESFKTKVSYLKQKGLGGAMVWALDLDDFAGFSCNQGRYPLIQTL 360 Query: 382 RQELSLPYLPSGTPELEVPKPGQPSEPEHGPSPGQDTFCQGKADGLYPNPRERSSFYSCA 441 RQELSLPYLPSGTPELEVPKPGQPSEPEHGPSPGQDTFCQGKADGLYPNPRERSSFYSCA Sbjct: 361 RQELSLPYLPSGTPELEVPKPGQPSEPEHGPSPGQDTFCQGKADGLYPNPRERSSFYSCA 420 Query: 442 AGRLFQQSCPTGLVFSNSCKCCTWN 466 AGRLFQQSCPTGLVFSNSCKCCTWN Sbjct: 421 AGRLFQQSCPTGLVFSNSCKCCTWN 445 >4WKA-A nrPDB Length = 377 Score = 571 bits (1472), Expect = e-163, Method: Composition-based stats. Identities = 368/373 (98%), Positives = 370/373 (99%), Gaps = 2/373 (0%) Query: 22 AKLVCYFTNWAQYRQGEARFLPKDLDPSLCTHLIYAFAGMTNHQLSTTEWNDETLYQEFN 81 AKLVCYFTNWAQYRQGEARFLPKDLDPSLCTHLIYAFAGMTNHQLSTTEWNDETLYQEFN Sbjct: 1 AKLVCYFTNWAQYRQGEARFLPKDLDPSLCTHLIYAFAGMTNHQLSTTEWNDETLYQEFN 60 Query: 82 GLKKMNPKLKTLLAIGGWNFGTQKFTDMVATANNRQTFVNSAIRFLRKYSFDGLDLDWEY 141 GLKKMNPKLKTLLAIGGWNFGTQKFTDMVATANNRQTFVNSAIRFLRKYSFDGLDLDWEY Sbjct: 61 GLKKMNPKLKTLLAIGGWNFGTQKFTDMVATANNRQTFVNSAIRFLRKYSFDGLDLDWEY 120 Query: 142 PGSQGSPAVDKERFTTLVQDLANAFQQEAQTSGKERLLLSAAVPAGQTYVDAGYEVDKIA 201 PGSQGSPAVDKERFTTLVQDLANAFQQEAQTSGKERLLLSAAVPAGQTYVDAGYEVDKIA Sbjct: 121 PGSQGSPAVDKERFTTLVQDLANAFQQEAQTSGKERLLLSAAVPAGQTYVDAGYEVDKIA 180 Query: 202 QNLDFVNLMAYDFHGSWEKVTGHNSPLYKRQEESGAAASLNVDAAVQQWLQKGTPASKLI 261 QNLDFVNLMAYDFHGSWEKVTGHNSPLYKRQEESGAAASLNVDAAVQQWLQKGTPASKLI Sbjct: 181 QNLDFVNLMAYDFHGSWEKVTGHNSPLYKRQEESGAAASLNVDAAVQQWLQKGTPASKLI 240 Query: 262 LGMPTYGRSFTLASSSDTRVGAPATGSGTPGPFTKEGGMLAYYEVCSWKGATKQRIQDQK 321 LGMPTYGRSFTLASSSDTRVGAPATGSGTPGPFTKEGGMLAYYEVCSWKGATKQRIQDQK Sbjct: 241 LGMPTYGRSFTLASSSDTRVGAPATGSGTPGPFTKEGGMLAYYEVCSWKGATKQRIQDQK 300 Query: 322 VPYIFRDNQWVGFDDVESFKTKVSYLKQKGLGGAMVWALDLDDFAGFSCNQGRYPLIQTL 381 VPYIFRDNQWVGFDDVESFKTKVSYLKQKGLGGAMVWALDLDDFAGFSCNQGRYPLIQTL Sbjct: 301 VPYIFRDNQWVGFDDVESFKTKVSYLKQKGLGGAMVWALDLDDFAGFSCNQGRYPLIQTL 360 Query: 382 RQELSLPYLPSGT 394 RQELSL +P G+ Sbjct: 361 RQELSL--VPRGS 371 >5WUS-A nrPDB Length = 460 Score = 568 bits (1465), Expect = e-162, Method: Composition-based stats. Identities = 191/451 (42%), Positives = 284/451 (62%), Gaps = 19/451 (4%) Query: 23 KLVCYFTNWAQYRQGEARFLPKDLDPSLCTHLIYAFAGMTNHQLSTTEWNDETLYQEFNG 82 +++CY T+W+ R RF+P+++DP+LCTH+IYAFA + +H+L+ + D +Y + Sbjct: 3 QVLCYLTSWSSKRPSAGRFMPENVDPTLCTHVIYAFATLKDHKLTEADEKDADMYDKVVA 62 Query: 83 LKKMNPKLKTLLAIGGWNFGTQKFTDMVATANNRQTFVNSAIRFLRKYSFDGLDLDWEYP 142 L++ NP LK LLAIGGW FG+ F ++ + FV AI FLR Y F+GLD+DWEYP Sbjct: 63 LREKNPNLKILLAIGGWAFGSTPFKELTSNVFRMNQFVYEAIEFLRDYQFNGLDVDWEYP 122 Query: 143 GSQGSPAVDKERFTTLVQDLANAFQQEAQTSGKERLLLSAAVPAGQTYVDAGYEVDKIAQ 202 A D+ F +L+++L AF+ EA+TSG+ RLLL+AAVPA + AGY+V +I++ Sbjct: 123 RG----ADDRAAFVSLLKELRLAFEGEAKTSGQPRLLLTAAVPASFEAIAAGYDVPEISK 178 Query: 203 NLDFVNLMAYDFHGSWEKVTGHNSPLYKRQEESGAAASLNVDAAVQQWLQKGTPASKLIL 262 LDF+N+M YDFHG WE+ GHNSPL+ + + L VD + ++W+++G P KL++ Sbjct: 179 YLDFINVMTYDFHGQWERQVGHNSPLFPLESATSYQKKLTVDYSAREWVRQGAPKEKLMI 238 Query: 263 GMPTYGRSFTLASSSDTRVGAPATGSGTPGPFTKEGGMLAYYEVCSWK---GATKQRIQD 319 GMPTYGRSFTL + + +GAPA+G G G FT E G ++YYE+C + T + Sbjct: 239 GMPTYGRSFTLINDTQFDIGAPASGGGQAGRFTNEAGFMSYYEICEFLREDNTTLVWDNE 298 Query: 320 QKVPYIFRDNQWVGFDDVESFKTKVSYLKQKGLGGAMVWALDLDDFAGFSCNQGRYPLIQ 379 Q VP+ +R++QWVGFDD S KTK+++LK++G GG MVW++D+DDF G SC G+YPLI Sbjct: 299 QMVPFAYREDQWVGFDDERSLKTKMAWLKEEGFGGIMVWSVDMDDFRG-SCGTGKYPLIT 357 Query: 380 TLRQELSLPYLPSGTPELEVPKPGQPSEP--EHGPSPGQDTFCQGKADGLYPNPRERSS- 436 ++QELS + +LE P + S P ++ + C+ + DG ++ + Sbjct: 358 AMKQELSGYKV-----KLEYDGPYESSSPTGQYTTKDPHEVTCE-EEDGHISYHKDHADC 411 Query: 437 --FYSCAAGRLFQQSCPTGLVFSNSCKCCTW 465 +Y C R CP+ LVF+ + C W Sbjct: 412 TMYYMCEGERKHHMPCPSNLVFNPNENVCDW 442 >3RM8-A nrPDB Length = 395 Score = 526 bits (1354), Expect = e-149, Method: Composition-based stats. Identities = 216/389 (55%), Positives = 278/389 (71%), Gaps = 9/389 (2%) Query: 22 AKLVCYFTNWAQYRQGEARFLPKDLDPSLCTHLIYAFAGMTNHQLSTTEWNDETLYQEFN 81 +L CYFTNWAQYR G RF+P D++P LCTHLIYAFAGM N++++T EWND TLYQ FN Sbjct: 1 YQLTCYFTNWAQYRPGLGRFMPDDINPCLCTHLIYAFAGMQNNEITTIEWNDVTLYQAFN 60 Query: 82 GLKKMNPKLKTLLAIGGWNFGTQKFTDMVATANNRQTFVNSAIRFLRKYSFDGLDLDWEY 141 GLK N +LKTLLAIGGWNFGT FT MV+T NRQTF+ S I+FLR+Y FDGLD DWEY Sbjct: 61 GLKNKNSQLKTLLAIGGWNFGTAPFTAMVSTPENRQTFITSVIKFLRQYEFDGLDFDWEY 120 Query: 142 PGSQGSPAVDKERFTTLVQDLANAFQQEAQTSGKERLLLSAAVPAGQTYVDAGYEVDKIA 201 PGS+GSP DK FT LVQ++ AF+QEA+ K RL+++AAV AG + + +GYE+ +++ Sbjct: 121 PGSRGSPPQDKHLFTVLVQEMREAFEQEAKQINKPRLMVTAAVAAGISNIQSGYEIPQLS 180 Query: 202 QNLDFVNLMAYDFHGSWEKVTGHNSPLYKRQEESGAAASLNVDAAVQQWLQKGTPASKLI 261 Q LD++++M YD HGSWE TG NSPLYK ++G+ A LNVD + W G PA KLI Sbjct: 181 QYLDYIHVMTYDLHGSWEGYTGENSPLYKYPTDTGSNAYLNVDYVMNYWKDNGAPAEKLI 240 Query: 262 LGMPTYGRSFTLASSSDTRVGAPATGSGTPGPFTKEGGMLAYYEVCSW--KGATKQRIQD 319 +G PTYG +F L++ S+T +GAP +G+G GP+ KE G+ AYYE+C++ GAT+ Sbjct: 241 VGFPTYGHNFILSNPSNTGIGAPTSGAGPAGPYAKESGIWAYYEICTFLKNGATQGWDAP 300 Query: 320 QKVPYIFRDNQWVGFDDVESFKTKVSYLKQKGLGGAMVWALDLDDFAGFSCNQGRYPLIQ 379 Q+VPY ++ N WVG+D+V+SF K +LK GGAMVWA+DLDDF G CNQG++PLI Sbjct: 301 QEVPYAYQGNVWVGYDNVKSFDIKAQWLKHNKFGGAMVWAIDLDDFTGTFCNQGKFPLIS 360 Query: 380 TLRQELSLPYLPSGTPELEVPKPGQPSEP 408 TL++ L G P QP EP Sbjct: 361 TLKKAL-------GLQSASCTAPAQPIEP 382 >6G9C-A nrPDB Length = 495 Score = 523 bits (1347), Expect = e-149, Method: Composition-based stats. Identities = 194/447 (43%), Positives = 266/447 (59%), Gaps = 14/447 (3%) Query: 26 CYFTNWAQYRQGEARFLPKDLDPSLCTHLIYAFAGMTNH-QLSTTEWND-ETLYQEFNGL 83 CYFTNWAQYR G ++ P+ +LC ++ YAFA + + + EWND + LY Sbjct: 37 CYFTNWAQYRPGNGKYNPEHYQANLCEYIFYAFAKLNDDFTVDQFEWNDIDVLYPGVMKQ 96 Query: 84 KKMNPKLKTLLAIGGWNFGTQKFTDMVATANNRQTFVNSAIRFLRKYSFDGLDLDWEYPG 143 K P LK LL++GGWN GT F M AT +NR F++S + FL++ FDG DLDWEYP Sbjct: 97 KSSQPDLKVLLSLGGWNAGTATFKKMAATYSNRAKFISSLVSFLQQNKFDGFDLDWEYPE 156 Query: 144 SQGSPAVDKERFTTLVQDLANAFQQEAQTSGKERLLLSAAVPAGQTYVDAGYEVDKIAQN 203 S DKE + L Q++ F++ A+ + RLL +AAV A VDAGY+V +A+ Sbjct: 157 S-----SDKENYLLLCQEILAKFEEVAKCTSTSRLLFTAAVSANPKTVDAGYDVPALAKV 211 Query: 204 LDFVNLMAYDFHGSWEKVTGHNSPLYKRQEESGAAASLNVDAAVQQWLQKGTPASKLILG 263 LDFVNLM YDFHG+WE TG NSPLY R+E+S NV+ + + W KG P ++I+G Sbjct: 212 LDFVNLMCYDFHGAWETQTGINSPLYSRKEDSSEFKMWNVEQSSKYWSDKGMPKKQIIIG 271 Query: 264 MPTYGRSFTLASSSDTRVGAPATGSGTPGPFTKEGGMLAYYEVCSWK--GATKQRIQDQK 321 +PTYGR +TL+ +S T +GAPA GS T + +E G+++YYEVC GA + + K Sbjct: 272 LPTYGRGWTLSDASKTDIGAPAQGSSTATEYLREAGVISYYEVCQKLSSGAKRVWDDESK 331 Query: 322 VPYIFRDNQWVGFDDVESFKTKVSYLKQKGLGGAMVWALDLDDFAGFSC---NQGRYPLI 378 PY+ + NQW +DDVES K K++++KQ+ GGA VW LD DDF G C N +YPLI Sbjct: 332 TPYLVQGNQWFSYDDVESMKAKINWIKQENYGGAFVWTLDYDDFLGSFCTEHNGKKYPLI 391 Query: 379 QTLRQELSLPYLPSGTPELEVPKPGQPSEPEHGPSPGQDTFCQGKADGLYPNPRERSSFY 438 +++ L Y+P T PS SP C +DGL+P+P S+FY Sbjct: 392 SLMQEILGGGYVPPSTESTTSQVTTTPSTTTSTTSPAGAFQC--PSDGLFPDPESCSNFY 449 Query: 439 SCAAGRLFQQSCPTGLVFSNSCKCCTW 465 CA G ++ CPTGL+F+ C + Sbjct: 450 QCAGGTAYKMKCPTGLMFNPKTSTCDY 476 >5XEP-A nrPDB Length = 381 Score = 514 bits (1324), Expect = e-146, Method: Composition-based stats. Identities = 193/388 (49%), Positives = 269/388 (69%), Gaps = 9/388 (2%) Query: 1 MVRSVAWAGFMVLLMIPWGSAAKLVCYFTNWAQYRQGEARFLPKDLDPSLCTHLIYAFAG 60 M A GF VL+++ SA KLVCYFT+W+QYR+G FLP + P LCTH+IY+FA Sbjct: 1 MGMRAALTGFAVLMLLQSCSAYKLVCYFTSWSQYREGVGSFLPDAIQPFLCTHIIYSFAN 60 Query: 61 MT-NHQLSTTEWNDETLYQEFNGLKKMNPKLKTLLAIGGWNFGTQKFTDMVATANNRQTF 119 ++ ++ LST EWNDE+ Y + N LK N LKTLL++GGW FG ++F+++ + R F Sbjct: 61 ISSDNMLSTWEWNDESNYDKLNKLKTRNTNLKTLLSVGGWKFGGKRFSEIASNTERRTAF 120 Query: 120 VNSAIRFLRKYSFDGLDLDWEYPGSQGSPAVDKERFTTLVQDLANAFQQEAQTSGKERLL 179 V S FLR Y FDGLDL W YP + DK+ F+TL+++L F +E G+E+LL Sbjct: 121 VRSVAPFLRSYGFDGLDLAWLYPRLR-----DKQYFSTLIKELNAEFTKE-VQPGREKLL 174 Query: 180 LSAAVPAGQTYVDAGYEVDKIAQNLDFVNLMAYDFHGSWEKVTGHNSPLYKRQEESGAAA 239 LSAA+ AG+ +D GY++ +IAQ+LDF+NLM YDFHG W ++TGH+SPL++ Q+++ Sbjct: 175 LSAALSAGKVAIDTGYDIAQIAQHLDFINLMTYDFHGVWRQITGHHSPLFQGQKDTRFDR 234 Query: 240 SLNVDAAVQQWLQKGTPASKLILGMPTYGRSFTLASSSDTRVGAPATGSGTPGPFTKEGG 299 NV+ AVQ ++ G ASKL++G+PT+G+SFTLAS S+ ++GAP +G G PG FTKE G Sbjct: 235 YSNVNYAVQYMIRLGAQASKLLMGIPTFGKSFTLAS-SENQLGAPISGEGLPGRFTKEAG 293 Query: 300 MLAYYEVCSW-KGATKQRIQDQKVPYIFRDNQWVGFDDVESFKTKVSYLKQKGLGGAMVW 358 LAYYE+C + KGA R+ ++KVP+ + NQWVG++D ES K KV +LK+K L GAMVW Sbjct: 294 TLAYYEICDFLKGAEVHRLSNEKVPFATKGNQWVGYEDKESVKNKVRFLKEKKLAGAMVW 353 Query: 359 ALDLDDFAGFSCNQGRYPLIQTLRQELS 386 ALDLDDF G + +PL ++ L+ Sbjct: 354 ALDLDDFQGTCQPKEFFPLTNAIKDALA 381 >1HJW-A nrPDB Length = 362 Score = 499 bits (1284), Expect = e-141, Method: Composition-based stats. Identities = 196/368 (53%), Positives = 262/368 (71%), Gaps = 9/368 (2%) Query: 22 AKLVCYFTNWAQYRQGEARFLPKDLDPSLCTHLIYAFAGMTNHQLSTTEWNDETLYQEFN 81 KLVCY+T+W+QYR+G+ P LD LCTH+IY+FA ++N + T EWND TLY N Sbjct: 1 YKLVCYYTSWSQYREGDGSCFPDALDRFLCTHIIYSFANISNDHIDTWEWNDVTLYGMLN 60 Query: 82 GLKKMNPKLKTLLAIGGWNFGTQKFTDMVATANNRQTFVNSAIRFLRKYSFDGLDLDWEY 141 LK NP LKTLL++GGWNFG+Q+F+ + + +R+TF+ S FLR + FDGLDL W Y Sbjct: 61 TLKNRNPNLKTLLSVGGWNFGSQRFSKIASNTQSRRTFIKSVPPFLRTHGFDGLDLAWLY 120 Query: 142 PGSQGSPAVDKERFTTLVQDLANAFQQEAQTSGKERLLLSAAVPAGQTYVDAGYEVDKIA 201 PG + DK+ FTTL++++ F +EAQ GK++LLLSAA+ AG+ +D+ Y++ KI+ Sbjct: 121 PGRR-----DKQHFTTLIKEMKAEFIKEAQ-PGKKQLLLSAALSAGKVTIDSSYDIAKIS 174 Query: 202 QNLDFVNLMAYDFHGSWEKVTGHNSPLYKRQEESGAAASLNVDAAVQQWLQKGTPASKLI 261 Q+LDF+++M YDFHG+W TGH+SPL++ QE++ N D AV L+ G PASKL+ Sbjct: 175 QHLDFISIMTYDFHGAWRGTTGHHSPLFRGQEDASPDRFSNTDYAVGYMLRLGAPASKLV 234 Query: 262 LGMPTYGRSFTLASSSDTRVGAPATGSGTPGPFTKEGGMLAYYEVCSW-KGATKQRIQDQ 320 +G+PT+GRSFTLAS S+T VGAP +G G PG FTKE G LAYYE+C + +GAT RI Q Sbjct: 235 MGIPTFGRSFTLAS-SETGVGAPISGPGIPGRFTKEAGTLAYYEICDFLRGATVHRILGQ 293 Query: 321 KVPYIFRDNQWVGFDDVESFKTKVSYLKQKGLGGAMVWALDLDDFAGFSCNQG-RYPLIQ 379 +VPY + NQWVG+DD ES K+KV YLK + L GAMVWALDLDDF G C Q R+PL Sbjct: 294 QVPYATKGNQWVGYDDQESVKSKVQYLKDRQLAGAMVWALDLDDFQGSFCGQDLRFPLTN 353 Query: 380 TLRQELSL 387 ++ L+ Sbjct: 354 AIKDALAA 361 >5WV8-A nrPDB Length = 482 Score = 485 bits (1248), Expect = e-137, Method: Composition-based stats. Identities = 190/374 (50%), Positives = 249/374 (66%), Gaps = 13/374 (3%) Query: 21 AAKLVCYFTNWAQYRQGEARFLPKDLDPSLCTHLIYAFAGMTNHQLSTTEWNDET----- 75 K+VCY+TNW+QYR +F+P+D+ P LCTH+I+AF + +LS+ E NDET Sbjct: 92 GYKIVCYYTNWSQYRTKIGKFMPEDIQPELCTHIIFAFGWLKKGKLSSFESNDETKDGKT 151 Query: 76 -LYQEFNGLKKMNPKLKTLLAIGGWNFGTQKFTDMVATANNRQTFVNSAIRFLRKYSFDG 134 LY N LKK NPKLKTLLAIGGW+FGTQKF +M AT RQTF+ SAI +LR +FDG Sbjct: 152 GLYDRINALKKANPKLKTLLAIGGWSFGTQKFKEMSATRYARQTFIYSAIPYLRDRNFDG 211 Query: 135 LDLDWEYPGSQGSPAVDKERFTTLVQDLANAFQQEAQTSGKERLLLSAAVPAGQTYVDAG 194 LD+DW YP DK+ + L+++L AF+ EAQ K RLLL+AAVP G + +G Sbjct: 212 LDIDWLYPKG----GDDKKNYVLLLKELREAFEAEAQEVKKPRLLLTAAVPVGPDNIKSG 267 Query: 195 YEVDKIAQNLDFVNLMAYDFHGSWEKVTGHNSPLYKRQEESGAAASLNVDAAVQQWLQKG 254 Y+V +A LDF+NLMAYDFHG WE+ TGHN+PLY +S L+VD A W++ G Sbjct: 268 YDVPAVASYLDFINLMAYDFHGKWERETGHNAPLYAPSSDSEWRKQLSVDHAAHLWVKLG 327 Query: 255 TPASKLILGMPTYGRSFTLASSSDTRVGAPATGSGTPGPFTKEGGMLAYYEVCS--WKGA 312 P KLI+GMPTYGR+FTL++ ++ +V +PA+G G G +TKE G LAYYEVC G Sbjct: 328 APKEKLIIGMPTYGRTFTLSNPNNFKVNSPASGGGKAGEYTKESGFLAYYEVCEILRNGG 387 Query: 313 TKQRIQDQKVPYIFRDNQWVGFDDVESFKTKVSYLKQKGLGGAMVWALDLDDFAGFSCNQ 372 + KVPY +QWVGFDD +S + K+ ++K GGAMVW +D+DDF+G C Sbjct: 388 AYVWDDEMKVPYAIHGDQWVGFDDEKSIRNKMRWIKDNSFGGAMVWTVDMDDFSGGVCGG 447 Query: 373 G-RYPLIQTLRQEL 385 +YPLI +R+EL Sbjct: 448 NVKYPLIGAMREEL 461 >2QF8-A nrPDB Length = 361 Score = 476 bits (1225), Expect = e-134, Method: Composition-based stats. Identities = 186/367 (50%), Positives = 259/367 (70%), Gaps = 10/367 (2%) Query: 22 AKLVCYFTNWAQYRQGEARFLPKDLDPSLCTHLIYAFAGMTNHQLSTTEWNDETLYQEFN 81 KL+CY+T+W+QYR+G+ P +DP LCTH+IY+FA ++N+++ T EWND TLY N Sbjct: 1 YKLICYYTSWSQYREGDGSCFPDAIDPFLCTHVIYSFANISNNEIDTWEWNDVTLYDTLN 60 Query: 82 GLKKMNPKLKTLLAIGGWNFGTQKFTDMVATANNRQTFVNSAIRFLRKYSFDGLDLDWEY 141 LK NP LKTLL++GGWN+G+Q+F+ + + +R+TF+ S FLR + FDGLDL W + Sbjct: 61 TLKNRNPNLKTLLSVGGWNYGSQRFSKIASKTQSRRTFIKSVPPFLRTHGFDGLDLAWLW 120 Query: 142 PGSQGSPAVDKERFTTLVQDLANAFQQEAQTSGKERLLLSAAVPAGQTYVDAGYEVDKIA 201 PG + DK TTLV+++ F +EAQ +G E+LLLSAAV AG+ +D GY++ +I+ Sbjct: 121 PGWR-----DKRHLTTLVKEMKAEFVREAQ-AGTEQLLLSAAVTAGKIAIDRGYDIAQIS 174 Query: 202 QNLDFVNLMAYDFHGSWEKVTGHNSPLYKRQEESGAAASLNVDAAVQQWLQKGTPASKLI 261 ++LDF++L+ YDFHG+W + GH+SPL++ E++ + S N D AV L+ G PA+KL+ Sbjct: 175 RHLDFISLLTYDFHGAWRQTVGHHSPLFRGNEDASSRFS-NADYAVSYMLRLGAPANKLV 233 Query: 262 LGMPTYGRSFTLASSSDTRVGAPATGSGTPGPFTKEGGMLAYYEVCSW-KGATKQRIQDQ 320 +G+PT+GRS+TLAS S T VGAP +G G PG FTK G+LAYYE+C + GAT R +DQ Sbjct: 234 MGIPTFGRSYTLAS-SKTDVGAPISGPGIPGRFTKWKGILAYYEICDFLHGATTHRFRDQ 292 Query: 321 KVPYIFRDNQWVGFDDVESFKTKVSYLKQKGLGGAMVWALDLDDFAGFSCNQG-RYPLIQ 379 +VPY + NQWV +DD ES K K YLK + L GAMVWALDLDDF G C Q +PL Sbjct: 293 QVPYATKGNQWVAYDDQESVKNKARYLKNRQLAGAMVWALDLDDFRGTFCGQNLTFPLTS 352 Query: 380 TLRQELS 386 ++ L+ Sbjct: 353 AIKDVLA 359 >1E9L-A nrPDB Length = 377 Score = 471 bits (1211), Expect = e-133, Method: Composition-based stats. Identities = 177/376 (47%), Positives = 250/376 (66%), Gaps = 2/376 (0%) Query: 22 AKLVCYFTNWAQYRQGEARFLPKDLDPSLCTHLIYAFAGMTNHQLSTTEWNDETLYQEFN 81 +L+CY+T+WA+ R E F P ++DP LCTHLIYAFAGM N++++ T D Y+ N Sbjct: 1 YQLMCYYTSWAKDRPIEGSFKPGNIDPCLCTHLIYAFAGMQNNEITYTHEQDLRDYEALN 60 Query: 82 GLKKMNPKLKTLLAIGGWNFGTQKFTDMVATANNRQTFVNSAIRFLRKYSFDGLDLDWEY 141 GLK N +LKTLLAIGGW FG F+ MV+T NRQ F+ S IRFLR+Y+FDGL+LDW+Y Sbjct: 61 GLKDKNTELKTLLAIGGWKFGPAPFSAMVSTPQNRQIFIQSVIRFLRQYNFDGLNLDWQY 120 Query: 142 PGSQGSPAVDKERFTTLVQDLANAFQQEAQTSGKERLLLSAAVPAGQTYVDAGYEVDKIA 201 PGS+GSP DK F+ LV+++ AF++E+ RLLL++ + +GY++ +++ Sbjct: 121 PGSRGSPPKDKHLFSVLVKEMRKAFEEESVEKDIPRLLLTSTGAGIIDVIKSGYKIPELS 180 Query: 202 QNLDFVNLMAYDFHGSWEKVTGHNSPLYKRQEESGAAASLNVDAAVQQWLQKGTPASKLI 261 Q+LD++ +M YD H + TG NSPLYK + G +A LNVD+ + W G + KLI Sbjct: 181 QSLDYIQVMTYDLHDPKDGYTGENSPLYKSPYDIGKSADLNVDSIISYWKDHGAASEKLI 240 Query: 262 LGMPTYGRSFTLASSSDTRVGAPATGSGTPGPFTKEGGMLAYYEVCSWK--GATKQRIQD 319 +G P YG +F L+ S T +GAP +G PG +T E G+LAYYEVC++ GAT+ Sbjct: 241 VGFPAYGHTFILSDPSKTGIGAPTISTGPPGKYTDESGLLAYYEVCTFLNEGATEVWDAP 300 Query: 320 QKVPYIFRDNQWVGFDDVESFKTKVSYLKQKGLGGAMVWALDLDDFAGFSCNQGRYPLIQ 379 Q+VPY ++ N+WVG+D+V SFK K +LK LGGA+VW LD+DDF+G C+Q +PL Sbjct: 301 QEVPYAYQGNEWVGYDNVRSFKLKAQWLKDNNLGGAVVWPLDMDDFSGSFCHQRHFPLTS 360 Query: 380 TLRQELSLPYLPSGTP 395 TL+ +L++ P Sbjct: 361 TLKGDLNIHSASCKGP 376 >4P8U-A nrPDB Length = 371 Score = 469 bits (1207), Expect = e-132, Method: Composition-based stats. Identities = 189/368 (51%), Positives = 264/368 (71%), Gaps = 9/368 (2%) Query: 22 AKLVCYFTNWAQYRQGEARFLPKDLDPSLCTHLIYAFAGMTNHQLSTTEWNDETLYQEFN 81 KLVCYFTNW+Q RQ +F P+++DP LC+HLIY+FA + N+++ + ++ LYQ N Sbjct: 8 YKLVCYFTNWSQDRQEPGKFTPENIDPFLCSHLIYSFASIENNKVIIKDKSEVMLYQTIN 67 Query: 82 GLKKMNPKLKTLLAIGGWNFGTQKFTDMVATANNRQTFVNSAIRFLRKYSFDGLDLDWEY 141 LK NPKLK LL+IGG+ FG++ F MV ++ +R F+NS I FLR ++FDGLD+ W Y Sbjct: 68 SLKTKNPKLKILLSIGGYLFGSKGFHPMVDSSTSRLEFINSIILFLRNHNFDGLDVSWIY 127 Query: 142 PGSQGSPAVDKERFTTLVQDLANAFQQEAQTSGKERLLLSAAVPAGQTYVDAGYEVDKIA 201 P + FT L+ +LA AFQ++ S KERLLL+ V AG+ +D Y+V+K+A Sbjct: 128 P-----DQKENTHFTVLIHELAEAFQKDFTKSTKERLLLTVGVSAGRQMIDNSYQVEKLA 182 Query: 202 QNLDFVNLMAYDFHGSWEK--VTGHNSPLYKRQEESGAAASLNVDAAVQQWLQKGTPASK 259 ++LDF+NL+++DFHGSWEK +TGHNSPL K ++ G ++ NV+ AV W+ KG P+ K Sbjct: 183 KDLDFINLLSFDFHGSWEKPLITGHNSPLSKGWQDRGPSSYYNVEYAVGYWIHKGMPSEK 242 Query: 260 LILGMPTYGRSFTLASSSDTRVGAPATGSGTPGPFTKEGGMLAYYEVCSW-KGATKQRIQ 318 +++G+PTYG SFTLAS ++T VGAPA+G G GP T+ G LAYYE+C + KGA +Q Sbjct: 243 VVMGIPTYGHSFTLAS-AETTVGAPASGPGAAGPITESSGFLAYYEICQFLKGAKITWLQ 301 Query: 319 DQKVPYIFRDNQWVGFDDVESFKTKVSYLKQKGLGGAMVWALDLDDFAGFSCNQGRYPLI 378 DQ+VPY + NQWVG+DDV+S +TKV +LK LGGAM+W++D+DDF G SCNQG YPL+ Sbjct: 302 DQQVPYAVKGNQWVGYDDVKSMETKVQFLKNLNLGGAMIWSIDMDDFTGKSCNQGPYPLV 361 Query: 379 QTLRQELS 386 Q +++ L Sbjct: 362 QAVKRSLG 369 >3W4R-A nrPDB Length = 554 Score = 454 bits (1169), Expect = e-128, Method: Composition-based stats. Identities = 175/532 (32%), Positives = 256/532 (48%), Gaps = 91/532 (17%) Query: 17 PWGSAAKLVCYFTNWAQYRQGEARFLPKDLDPSLCTHLIYAFAGMTNHQLSTTEWN---- 72 S A++VCYF+NWA YR G R+ +D+ +CTH+IY+F G+T + Sbjct: 20 ESDSRARVVCYFSNWAVYRPGVGRYGIEDIPVDMCTHIIYSFIGVTEDTQQVLIIDPELD 79 Query: 73 -DETLYQEFNGLKKMNPKLKTLLAIGGWNFGTQKFTDMVATANNRQTFVNSAIRFLRKYS 131 D+ ++ F L+ +P +K +A+GGW G K++ MVA + R FV S + FL KY+ Sbjct: 80 VDKNGFKNFTSLRSKHPGVKFTVAVGGWAEGGSKYSKMVAAKSTRMAFVRSVVDFLNKYN 139 Query: 132 FDGLDLDWEYPG--SQGSPAVDKERFTTLVQDLANAFQQEAQTSGKERLLLSAAVPAGQT 189 FDGLDLDWEYPG +G DK++F LVQ+L AF +E + G E L+AAVP Sbjct: 140 FDGLDLDWEYPGAADRGGSFSDKDKFLYLVQELRRAFIREGK--GWE---LTAAVPLANF 194 Query: 190 YVDAGYEVDKIAQNLDFVNLMAYDFHGSWEKVTGHNSPLYKRQEESGAAASLNVDAAVQQ 249 + GY V ++ Q LD +++M+YD G+W +SPLYKR + A LNV+ +Q Sbjct: 195 RLMEGYHVPELCQELDAIHVMSYDLRGNWAGFADVHSPLYKRPHDQWAYEKLNVNDGLQL 254 Query: 250 WLQKGTPASKLILGMPTYGRSFTLASSSDTRVGAPA----TGSGTPGPFTKEGGMLAYYE 305 W KG P +KL++G+P YGRSFTL+S ++ G G P P+T G AYYE Sbjct: 255 WEDKGCPTNKLVVGIPFYGRSFTLSSGNNNYNLGTYINKEAGGGDPAPYTNATGFWAYYE 314 Query: 306 VCSWKG-----ATKQRIQDQKVPYIFRDNQWVGFDDVESFKTKVSYLKQKGLGGAMVWAL 360 +C+ TK+ + K PY ++ QWVG++D S + K++++K+KG GAM WA+ Sbjct: 315 ICTEVDTADSKWTKKWDEHGKCPYAYKGTQWVGYEDPRSVEIKMNWIKEKGYLGAMTWAI 374 Query: 361 DLDDFAGFSCNQGRYPLIQTLRQELSLPYLPS-------GTPELEVPKPGQPSEPEHG-- 411 D+DDF G + LI+ L + +S +P TPE P P PS+P G Sbjct: 375 DMDDFQGLC--GEKNILIKLLHKHMSAYTVPPPRSGNTTPTPEWARP-PSTPSDPSEGDP 431 Query: 412 --------PSPGQDTFCQGKADGLYPNPR------------------------------- 432 P+ + + A P P+ Sbjct: 432 IPTTTTSKPATSKPSTTSQPATTSRPEPKPTTSLPTPAPTASTTEEEAQQPEVELPAENE 491 Query: 433 -------------------ERSSFYSCAAGRLFQQSCPTGLVFSNSCKCCTW 465 + ++ C G Q C G VF+ C W Sbjct: 492 IGNSDKICTSEEDYIPDKKQCDKYWRCVNGEGMQFKCQPGTVFNVKLNVCDW 543 >3WKZ-A nrPDB Length = 395 Score = 429 bits (1104), Expect = e-120, Method: Composition-based stats. Identities = 152/393 (38%), Positives = 225/393 (57%), Gaps = 23/393 (5%) Query: 17 PWGSAAKLVCYFTNWAQYRQGEARFLPKDLDPSLCTHLIYAFAGMTNHQLSTTEWN---- 72 S A++VCYF+NWA YR G R+ +D+ +CTH+IY+F G+T + Sbjct: 2 ESDSRARVVCYFSNWAVYRPGVGRYGIEDIPVDMCTHIIYSFIGVTEDTQQVLIIDPELD 61 Query: 73 -DETLYQEFNGLKKMNPKLKTLLAIGGWNFGTQKFTDMVATANNRQTFVNSAIRFLRKYS 131 D+ ++ F L+ +P +K +A+GGW G K++ MVA + R FV S + FL KY+ Sbjct: 62 VDKNGFKNFTSLRSKHPGVKFTVAVGGWAEGGSKYSKMVAAKSTRMAFVRSVVDFLNKYN 121 Query: 132 FDGLDLDWEYPG--SQGSPAVDKERFTTLVQDLANAFQQEAQTSGKERLLLSAAVPAGQT 189 FDGLDLDW+YPG +G DK++F LVQ+L AF +E + G E L+AAVP Sbjct: 122 FDGLDLDWQYPGAADRGGSFSDKDKFLYLVQELRRAFIREGK--GWE---LTAAVPLANF 176 Query: 190 YVDAGYEVDKIAQNLDFVNLMAYDFHGSWEKVTGHNSPLYKRQEESGAAASLNVDAAVQQ 249 + GY V ++ Q LD +++M+YD G+W +SPLYKR + A LNV+ +Q Sbjct: 177 RLMEGYHVPELCQELDAIHVMSYDLRGNWAGFADVHSPLYKRPHDQWAYEKLNVNDGLQL 236 Query: 250 WLQKGTPASKLILGMPTYGRSFTLASSSDTRVGAPA----TGSGTPGPFTKEGGMLAYYE 305 W KG P +KL++G+P YGRSFTL+S ++ G G P P+T G AYYE Sbjct: 237 WEDKGCPTNKLVVGIPFYGRSFTLSSGNNNYNLGTYINKEAGGGDPAPYTNATGFWAYYE 296 Query: 306 VCSWKG-----ATKQRIQDQKVPYIFRDNQWVGFDDVESFKTKVSYLKQKGLGGAMVWAL 360 +C+ TK+ + K PY ++ QWVG++D S + K++++K+KG GAM WA+ Sbjct: 297 ICTEVDTADSKWTKKWDEHGKCPYAYKGTQWVGYEDPRSVEIKMNWIKEKGYLGAMTWAI 356 Query: 361 DLDDFAGFSCNQGRYPLIQTLRQELSLPYLPSG 393 D+DDF G + LI+ L + +S +P Sbjct: 357 DMDDFQGLC--GEKNILIKLLHKHMSAYTVPPP 387 >5Y29-A nrPDB Length = 377 Score = 422 bits (1084), Expect = e-118, Method: Composition-based stats. Identities = 160/385 (41%), Positives = 227/385 (58%), Gaps = 26/385 (6%) Query: 20 SAAKLVCYFTNWAQYRQGEARFLPKDLDPSLCTHLIYAFAGMTNHQLST--TEWND--ET 75 S KLVCY+TNW+ YR G ++ P+D+DPSLCTH++Y FA + N L T W+D Sbjct: 5 SRYKLVCYYTNWSWYRPGIGKYSPEDIDPSLCTHIVYGFAVLGNDGLMTAHDTWSDYDNR 64 Query: 76 LYQEFNGLKKMNPKLKTLLAIGGWNFGT-QKFTDMVATANNRQTFVNSAIRFLRKYSFDG 134 Y+ K+ +K LA+GGWN K++ +V R FV A+ FL KY FDG Sbjct: 65 FYERVVEYKRY--GIKVSLALGGWNDSAGDKYSKLVNDPAARAKFVQHAVAFLEKYGFDG 122 Query: 135 LDLDWEYPGS-----QGSPAVDKERFTTLVQDLANAFQQEAQTSGKERLLLSAAVPAGQT 189 LDLDWEYP P DK+ F LV +L+ + + LLLSAAV + Sbjct: 123 LDLDWEYPKCWQVDCSKGPDSDKQGFADLVHELSAVLKPKG-------LLLSAAVSPNKM 175 Query: 190 YVDAGYEVDKIAQNLDFVNLMAYDFHGSWEKVTGHNSPLYKRQEESGAAASLNVDAAVQQ 249 +DAGY+V +A+ LD++ +M YD+HG W+K TGH +PLY ++ N + + Sbjct: 176 VIDAGYDVPVLARLLDWIAVMTYDYHGQWDKKTGHVAPLYYHPDDD--TTYFNANYTIHY 233 Query: 250 WLQKGTPASKLILGMPTYGRSFTLASSSDTRVGAPATGSGTPGPFTKEGGMLAYYEVCSW 309 W++KGTPASK+++GMP YG+SFT+ + + P + G PG +T+ G LAYYE+C Sbjct: 234 WMEKGTPASKIVMGMPMYGQSFTIENRGIHGLNIPVSDGGEPGEYTRAKGFLAYYEICDR 293 Query: 310 K---GATKQRIQDQKV-PYIFRDNQWVGFDDVESFKTKVSYLKQKGLGGAMVWALDLDDF 365 G T + Q++ PY ++ NQWV FDDVE K KV+++K LGG M+WALDLDD+ Sbjct: 294 IRNSGWTVVKDPYQRMGPYAYKGNQWVSFDDVEIIKKKVNFIKSLNLGGGMIWALDLDDY 353 Query: 366 AGFSCNQGRYPLIQTLRQELSLPYL 390 C QG++PL+ ++ EL P + Sbjct: 354 RN-RCGQGKHPLLNAIKTELLNPKI 377 >5Y2C-A nrPDB Length = 383 Score = 420 bits (1079), Expect = e-118, Method: Composition-based stats. Identities = 148/388 (38%), Positives = 215/388 (55%), Gaps = 26/388 (6%) Query: 21 AAKLVCYFTNWAQYRQGEARFLPKDLDPSLCTHLIYAFAGMTNHQL---STTEWND--ET 75 K+VCY+TNWA YR ++ P D++P LCTH+IYAFA + +L S W D Sbjct: 2 RFKVVCYYTNWAWYRPDNGKYTPGDINPELCTHIIYAFAVLDKEELVIKSHDIWLDVENK 61 Query: 76 LYQEFNGLKKMNPKLKTLLAIGGWNFGT-QKFTDMVATANNRQTFVNSAIRFLRKYSFDG 134 Y++ LK +K LL +GGW+ K++ +V + R+ FV A+ FL +Y FDG Sbjct: 62 FYEKVTALKS--HGVKVLLGLGGWDDSAGDKYSRLVNNVSARRKFVVHAVDFLEQYGFDG 119 Query: 135 LDLDWEYP-----GSQGSPAVDKERFTTLVQDLANAFQQEAQTSGKERLLLSAAVPAGQT 189 LDLDW YP + P DK+ F LV++L AF + +LLSAAV A + Sbjct: 120 LDLDWLYPKCWQVECEKGPDSDKQGFADLVKELRKAFNRRG-------MLLSAAVSASKR 172 Query: 190 YVDAGYEVDKIAQNLDFVNLMAYDFHGSWEKVTGHNSPLYKRQEESGAAASLNVDAAVQQ 249 +D Y V ++ NLD+++LM YD+HG W+K TGH +P+Y +++ + NV+ V Sbjct: 173 VIDYAYNVPALSMNLDWISLMTYDYHGQWDKKTGHVAPMYVHDKDTD--NTFNVNFTVNY 230 Query: 250 WLQKGTPASKLILGMPTYGRSFTLASSSDTRVGAPATGSGTPGPFTKEGGMLAYYEVCS- 308 W+ KG KL++G+P YG+SF++ + T +GAP G G T+ G L++YE+C Sbjct: 231 WINKGADRKKLVVGVPFYGQSFSVVEGAGTGLGAPTYAGGEAGDETRARGFLSFYEICER 290 Query: 309 --WKGATKQRIQDQKV-PYIFRDNQWVGFDDVESFKTKVSYLKQKGLGGAMVWALDLDDF 365 KG R ++ PY D+QWV FDD + K Y++ LGG+M W+LDLDDF Sbjct: 291 VKVKGWKVHRDPGGRIGPYATHDDQWVSFDDDFMARHKAEYVRAMELGGSMAWSLDLDDF 350 Query: 366 AGFSCNQGRYPLIQTLRQELSLPYLPSG 393 G C G+ PL+ T+ L P Sbjct: 351 TGKYCGCGKAPLLTTINHVLRGKEAPPP 378 >6BT9-A nrPDB Length = 672 Score = 368 bits (946), Expect = e-102, Method: Composition-based stats. Identities = 141/457 (30%), Positives = 204/457 (44%), Gaps = 88/457 (19%) Query: 23 KLVCYFTNWAQYRQGEARFLPKDLDPSLCTHLIYAFAGM--------------------- 61 K+V YF +W Y + + D+D S THL YAFA + Sbjct: 38 KIVGYFPSWGVYGR---NYQVADIDASKLTHLNYAFADICWNGKHGNPSTHPDNPNKQTW 94 Query: 62 -----------------------------TNHQLSTTEWNDE------TLYQEFNGLKKM 86 ++ +S T W D + E LK Sbjct: 95 NCKESGVPLQNKEVPNGTLVLGEPWADVTKSYPVSGTTWEDCDKYARCGNFGELKRLKAK 154 Query: 87 NPKLKTLLAIGGWNFGTQKFTDMVATANNRQTFVNSAIRFLRKYSFDGLDLDWEYPGSQG 146 P LKT++++GGW + + +F+DM A R+ F S + FLR Y FDG+DLDWEYPG + Sbjct: 155 YPHLKTIISVGGWTW-SNRFSDMAADEKTRKVFAESTVAFLRAYGFDGVDLDWEYPGVET 213 Query: 147 SP-----AVDKERFTTLVQDLANAFQQEAQTSGKERLLLSAAVPAGQTYVDAGYEVDKIA 201 P DK+ FT L+QD+ NA + GK + LL+ A A Q Y D E+ KI+ Sbjct: 214 IPGGSYRPEDKQNFTLLLQDVRNALNKAGAEDGK-QYLLTIASGASQRYADHT-ELKKIS 271 Query: 202 QNLDFVNLMAYDFHGSWEKVTGHNSPLYKRQEESGAAASLNVDAAVQQWLQKGTPASKLI 261 Q LD++N+M YDFHG WE + HN+ LYK + A + VD A+ + +G P KL+ Sbjct: 272 QILDWINIMTYDFHGGWEATSNHNAALYKDPNDPAANTNFYVDGAINVYTNEGVPVDKLV 331 Query: 262 LGMPTYGRSFTLASSSDTRVGAPA---TGSGTPGPFTKEG------GMLAYYEV----CS 308 LG+P YGR + + P + T + G+ Y ++ + Sbjct: 332 LGVPFYGRGWKSCGKENNGQYQPCKPGSDGKLASKGTWDDYSTGDTGVYDYGDLAANYVN 391 Query: 309 WKGATKQRIQDQKVPYIFR--DNQWVGFDDVESFKTKVSYLKQKGLGGAMVWALDLD--D 364 G + KVPY++ ++ +DD ES K K Y+K KGL GAM W L D Sbjct: 392 KNGFVRYWNDTAKVPYLYNATTGTFISYDDNESMKYKTDYIKTKGLSGAMFWELSGDCRT 451 Query: 365 FAGFSCNQGRYPLIQTLRQELSLPYLPSGTPELEVPK 401 +SC+ + L+ TL +EL P + E P Sbjct: 452 SPKYSCSGPK--LLDTLVKELLGG--PINQKDTEPPT 484 >1ITX-A nrPDB Length = 419 Score = 356 bits (914), Expect = 1e-98, Method: Composition-based stats. Identities = 134/403 (33%), Positives = 198/403 (49%), Gaps = 69/403 (17%) Query: 22 AKLVCYFTNWAQYRQGEARFLPKDLDPSLCTHLIYAFAGM-------------------- 61 K+V Y+ +WA Y + + D+DP+ TH+ YAFA + Sbjct: 12 YKIVGYYPSWAAYGR---NYNVADIDPTKVTHINYAFADICWNGIHGNPDPSGPNPVTWT 68 Query: 62 ------------------------TNHQLSTTEWNDE--TLYQEFNGLKKMNPKLKTLLA 95 T + W+ + N LK+ NP LKT+++ Sbjct: 69 CQNEKSQTINVPNGTIVLGDPWIDTGKTFAGDTWDQPIAGNINQLNKLKQTNPNLKTIIS 128 Query: 96 IGGWNFGTQKFTDMVATANNRQTFVNSAIRFLRKYSFDGLDLDWEYPGSQGSP-----AV 150 +GGW + + +F+D+ ATA R+ F NSA+ FLRKY+FDG+DLDWEYP S G Sbjct: 129 VGGWTW-SNRFSDVAATAATREVFANSAVDFLRKYNFDGVDLDWEYPVSGGLDGNSKRPE 187 Query: 151 DKERFTTLVQDLANAFQQEAQTSGKERLLLSAAVPAGQTYVDAGYEVDKIAQNLDFVNLM 210 DK+ +T L+ + GK + LL+ A A TY A E+ KIA +D++N+M Sbjct: 188 DKQNYTLLLSKIREKLDAAGAVDGK-KYLLTIASGASATYA-ANTELAKIAAIVDWINIM 245 Query: 211 AYDFHGSWEKVTGHNSPLYKRQEESGA----AASLNVDAAVQQWLQKGTPASKLILGMPT 266 YDF+G+W+K++ HN+PL S A A + NV A Q L G PA+KL+LG+P Sbjct: 246 TYDFNGAWQKISAHNAPLNYDPAASAAGVPDANTFNVAAGAQGHLDAGVPAAKLVLGVPF 305 Query: 267 YGRSFTLASSSDTRVGAPATGSGTPGPFTKEGGMLAYYEV----CSWKGATKQRIQDQKV 322 YGR + + + TG + G T E G +Y++ + G T+ KV Sbjct: 306 YGRGWDGCAQAGNGQYQTCTGGSSVG--TWEAGSFDFYDLEANYINKNGYTRYWNDTAKV 363 Query: 323 PYIFRDNQ--WVGFDDVESFKTKVSYLKQKGLGGAMVWALDLD 363 PY++ + ++ +DD ES K +Y+K KGLGGAM W L D Sbjct: 364 PYLYNASNKRFISYDDAESVGYKTAYIKSKGLGGAMFWELSGD 406 >5GZU-A nrPDB Length = 885 Score = 341 bits (874), Expect = 5e-94, Method: Composition-based stats. Identities = 125/400 (31%), Positives = 185/400 (46%), Gaps = 55/400 (13%) Query: 23 KLVCYFTNWAQYRQGEARFLPKDLDPSLCTHLIYAFAGMTNHQLSTTEWN---------- 72 K+V Y W + + E +D + THL YAF + N ++ T + + Sbjct: 27 KIVSYIPAWVDWAKDERG-----VDATKFTHLYYAFGRINNGKVVTIKEDAKWTEDPTIT 81 Query: 73 -----------DETLYQEFNGLKKMNPKLKTLLAIGGWNFGTQKFTDMVATANNRQTFVN 121 DE+ GLK NP LK L++IGGW + F+D T +R+ F N Sbjct: 82 EADRIKRRNNPDESNLAYLTGLKAKNPNLKVLVSIGGW--EAEGFSDAALTPESREVFAN 139 Query: 122 SAIRFLRKYSFDGLDLDWEYP-----GSQGSPAVDKERFTTLVQDLANAFQQEAQTSGKE 176 SA+ F+ KY+ DG+DLDWEYP G S DK FT L++ L ++ T+ K Sbjct: 140 SALDFMNKYNLDGIDLDWEYPVYGAWGVIKSRPEDKANFTALLKLLREKLDAQSTTTNK- 198 Query: 177 RLLLSAAVPAGQTYVDAGYEVDKIAQNLDFVNLMAYDFHGSWEKVTGHNSPLYKRQEESG 236 L+ A A +TY D+ E+ KI LD++NLM YD HG W+ T H++ +Y S Sbjct: 199 YYELAIAAGASKTYTDS-VELTKITPYLDYINLMTYDLHGGWDPATSHHTAVY-----SA 252 Query: 237 AAASLNVDAAVQQWLQKGTPASKLILGMPTYGRSFTLASSSDTRVGAPA-TGSGTPGPFT 295 L+VD+ V+ +L G PA KL++G Y R + + T + A + +G+PG Sbjct: 253 TNNQLSVDSTVKLYLNNGVPAEKLMVGGAFYSRVWQNVENKGTGLSEKAGSQAGSPGTIV 312 Query: 296 KEGGMLAYYEVCSWKGATKQRIQDQKVPYIFRDNQWVGFDDVESFKTKVSYLKQKGLGGA 355 + Y + G T+ K PY+F + ++ ++D S K Y+KQ L G Sbjct: 313 YSELVNNY---INKNGYTRYWDDTAKAPYLFNGSTFISYEDTASAAYKAEYIKQNNLAGF 369 Query: 356 MVWALDLDDFAGFSCNQGRYPLIQTLRQELSLPYLPSGTP 395 M W D + L T+ L Y SGTP Sbjct: 370 MYWEYSQD--------SDSHELANTIYSRL---YAKSGTP 398 Score = 317 bits (813), Expect = 6e-87, Method: Composition-based stats. Identities = 115/395 (29%), Positives = 178/395 (45%), Gaps = 55/395 (13%) Query: 24 LVCYFTNWAQYRQGEARFLPKDLDPSLCTHLIYAFAGMTNHQLSTTEWN----------- 72 L+ Y W + + +D + TH+ YAFA + ++++ + Sbjct: 515 LLGYVPGWVDWTNSAYK-----VDATKLTHINYAFARIKDNKVVKISEDINWVNEFPSEE 569 Query: 73 ---------DETLYQEFNGLKKMNPKLKTLLAIGGWNFGTQKFTDMVATANNRQTFVNSA 123 D+ + LK+ NP LK L++IGGW + F+D T R+ NSA Sbjct: 570 IREQRRNNPDDANFAYLKTLKQQNPSLKVLVSIGGW--AAEGFSDAALTPETREELANSA 627 Query: 124 IRFLRKYSFDGLDLDWEYP-----GSQGSPAVDKERFTTLVQDLANAFQQEAQTSGKERL 178 I F+ +Y FDG+DLDWEYP G S DK+ FT L++ E GK Sbjct: 628 IAFMHQYGFDGIDLDWEYPVYGAFGVIKSRPEDKQNFTALLKLFREKLDVEGALHGK-YY 686 Query: 179 LLSAAVPAGQTYVDAGYEVDKIAQNLDFVNLMAYDFHGSWEKVTGHNSPLYKRQEESGAA 238 L+ A A Y+++ E+DKI Q LD++++M YD+HGSWE T H + +Y G Sbjct: 687 ELAIASAAAPIYINS-VELDKIHQYLDYMSVMTYDYHGSWESKTAHQASVYTSALSPG-- 743 Query: 239 ASLNVDAAVQQWLQKGTPASKLILGMPTYGRSFTLASSSDTRVGAPATGSG-TPGPFTKE 297 + D+ + + ++G PASKL++G Y R + + + + A PG T Sbjct: 744 -DFSADSVLTAYRKQGVPASKLVIGGAFYARGWVNVPNINHGLFQQAGDQAKNPGTPTYN 802 Query: 298 GGMLAYYEVCSWKGATKQRIQDQKVPYIF----RDNQWVGFDDVESFKTKVSYLKQKGLG 353 + Y++ KG T+ K PY++ ++ +DD ES K K Y K +GL Sbjct: 803 DLVKDYFD----KGYTRYWDNSAKAPYLYNPDANGGTFITYDDEESLKYKAEYAKNQGLR 858 Query: 354 GAMVWALDLDDFAGFSCNQGRYPLIQTLRQELSLP 388 G M W D +G L+ + EL P Sbjct: 859 GVMFWDYSQD-ISGK--------LLGAIFNELKAP 884 >3AQU-A nrPDB Length = 356 Score = 339 bits (870), Expect = 1e-93, Method: Composition-based stats. Identities = 123/344 (35%), Positives = 179/344 (52%), Gaps = 20/344 (5%) Query: 32 AQYRQGEARFLPKDLDPSLCTHLIYAFAGMTN--HQLSTTEWNDETLYQEFNGLKKMNPK 89 A Y + F D+D SL THL AFA + + +Q++ + N +++ NP Sbjct: 7 ASYWFPASEFPVTDIDSSLFTHLFCAFADLNSQTNQVTVSSANQPKFSTFTQTVQRRNPS 66 Query: 90 LKTLLAIGGWNFGTQKFTDMVATANNRQTFVNSAIRFLRKYSFDGLDLDWEYPGSQGSPA 149 +KTLL+IGG + M + +R++F++S+IR R Y F GLDLDWEYP S A Sbjct: 67 VKTLLSIGGGIADKTAYASMASNPTSRKSFIDSSIRVARSYGFHGLDLDWEYP----SSA 122 Query: 150 VDKERFTTLVQDLANAFQQEAQTSGKERLLLSAAVPAGQTYVDAGYEVDKIAQNLDFVNL 209 + F TL+++ +A EA +SGK RLLL+AAV Y Y V +A +LD+VNL Sbjct: 123 TEMTNFGTLLREWRSAVVAEASSSGKPRLLLAAAVFYSNNYYSVLYPVSAVASSLDWVNL 182 Query: 210 MAYDFHG-SWEKVTGHNSPLYKRQEESGAAASLNVDAAVQQWLQKGTPASKLILGMPTYG 268 MAYDF+G W +VTG + L+ + DA + W+Q G PA K +LG P YG Sbjct: 183 MAYDFYGPGWSRVTGPPAALFDPSNAGP-----SGDAGTRSWIQAGLPAKKAVLGFPYYG 237 Query: 269 RSFTLASSSDTRVGAPATGSGTPGPFTKEGGMLAYYEVCSW---KGATKQRIQDQKVPYI 325 ++ L +++ AP TG+ G + Y ++ + GAT Y Sbjct: 238 YAWRLTNANSHSYYAPTTGAA-----ISPDGSIGYGQIRKFIVDNGATTVYNSTVVGDYC 292 Query: 326 FRDNQWVGFDDVESFKTKVSYLKQKGLGGAMVWALDLDDFAGFS 369 + W+G+DD +S TKV Y KQ+GL G W + DD +G S Sbjct: 293 YAGTNWIGYDDNQSIVTKVRYAKQRGLLGYFSWHVGADDNSGLS 336 >3CHF-A nrPDB Length = 433 Score = 334 bits (856), Expect = 6e-92, Method: Composition-based stats. Identities = 120/406 (29%), Positives = 176/406 (43%), Gaps = 49/406 (12%) Query: 20 SAAKLVCYFTNWAQYRQGEARFLPKDLDPSLCTHLIYAFAGMT---------------NH 64 S + V YF NWA Y + P+DL TH++YAFA + Sbjct: 41 SGYRSVVYFVNWAIYGRNH---NPQDLPVERLTHVLYAFANVRPETGEVYMTDSWADIEK 97 Query: 65 QLSTTEWNDETLY-----QEFNGLKKMNPKLKTLLAIGGWNFGTQKFTDMVATANNRQTF 119 W+D ++ LKK N LK LL+IGGW + + F +T R+ F Sbjct: 98 HYPGDSWSDTGNNVYGCIKQLYLLKKQNRNLKVLLSIGGWTY-SPNFAPAASTDAGRKNF 156 Query: 120 VNSAIRFLRKYSFDGLDLDWEYPGSQGSPAVDKERFTTLVQDLANAFQQE-AQTSGKERL 178 +A++ L+ FDGLD+DWEYP + F L++++ A A +G + Sbjct: 157 AKTAVKLLQDLGFDGLDIDWEYPENDQQ----ANDFVLLLKEVRTALDSYSAANAGGQHF 212 Query: 179 LLSAAVPAGQTYVDAGYEVDKIAQNLDFVNLMAYDFHGSWEKVTGHNSPLYKRQEESGAA 238 LL+ A PAG + + + Q LDF NLMAYD+ GS+ ++GH + +Y + Sbjct: 213 LLTVASPAGPDKIKV-LHLKDMDQQLDFWNLMAYDYAGSFSSLSGHQANVYNDTSNP-LS 270 Query: 239 ASLNVDAAVQQWLQKGTPASKLILGMPTYGRSFTLASSSDTRVGAPATGSGTPGPFTKEG 298 N A+ + G PA+K++LGMP YGRSF G P G G + E Sbjct: 271 TPFNTQTALDLYRAGGVPANKIVLGMPLYGRSFANTD----GPGKPYNG---VGQGSWEN 323 Query: 299 GMLAYYEVCSWKGATKQRIQDQKVPYIFRDNQ--WVGFDDVESFKTKVSYLKQKGLGGAM 356 G+ Y + GAT+ + D Y + + +D+ + K Y+K GLGGAM Sbjct: 324 GVWDYKAL-PQAGATEHVLPDIMASYSYDATNKFLISYDNPQVANLKSGYIKSLGLGGAM 382 Query: 357 VWALDLDDFAGFSCNQGRYPLIQTLRQELSLPYL-PSGTPELEVPK 401 W D G LI T+ L + EL+ P Sbjct: 383 WWDSSSD-------KTGSDSLITTVVNALGGTGVFEQSQNELDYPV 421 >3G6L-A nrPDB Length = 406 Score = 331 bits (850), Expect = 3e-91, Method: Composition-based stats. Identities = 115/360 (31%), Positives = 166/360 (46%), Gaps = 40/360 (11%) Query: 26 CYFTNWAQYRQGEARFLPKDLDPSLCTHLIYAFAGMT--------------NHQLSTTEW 71 YFTNW Y + F P DL S H++Y+F + S W Sbjct: 25 VYFTNWGIYGR---NFQPADLQASKILHVLYSFMNLRVDGTVYSGDTYADLEKHYSDDSW 81 Query: 72 NDETL-----YQEFNGLKKMNPKLKTLLAIGGWNFGTQKFTDMVATANNRQTFVNSAIRF 126 ND ++ LKK N LK +L+IGGW + T F +T R TF +A+ F Sbjct: 82 NDIGTNAYGCVKQLYKLKKANRSLKIMLSIGGWTWSTN-FPAAASTEATRATFAKTAVEF 140 Query: 127 LRKYSFDGLDLDWEYPGSQGSPAVDKERFTTLVQDLANAFQQEAQT-SGKERLLLSAAVP 185 ++ + FDG+D+DWEYP S+ D L+Q + + T + LS A P Sbjct: 141 MKDWGFDGIDVDWEYPASE----TDANNMVLLLQRVRQELDSYSATYANGYHFQLSIAAP 196 Query: 186 AGQTYVDAGYEVDKIAQNLDFVNLMAYDFHGSWEKVTGHNSPLYKRQEESGAAASLNVDA 245 AG ++ + ++ ++ LD +NLMAYD+ GSW+ V+GH + LY + + A Sbjct: 197 AGPSHYNV-LKLAQLGSVLDNINLMAYDYAGSWDSVSGHQTNLYPSTSNPS-STPFSTKA 254 Query: 246 AVQQWLQKGTPASKLILGMPTYGRSFTLASSSDTRVGAPATGSGTPGPFTKEGGMLAYYE 305 AV ++ G PASK+ILGMP YGR+F P T G + E G+ Y + Sbjct: 255 AVDAYIAAGVPASKIILGMPIYGRAFVGTDG-------PGKPYSTIGEGSWESGIWDY-K 306 Query: 306 VCSWKGATKQRIQDQKVPYIFRDN--QWVGFDDVESFKTKVSYLKQKGLGGAMVWALDLD 363 V GAT Y + + + +D + +TKVSY K GLGG+M W D Sbjct: 307 VLPKAGATVITDSAAGATYSYDSSSRTMISYDTPDMVRTKVSYAKGLGLGGSMFWEASAD 366 >4MNK-A nrPDB Length = 348 Score = 331 bits (849), Expect = 3e-91, Method: Composition-based stats. Identities = 123/342 (35%), Positives = 184/342 (53%), Gaps = 27/342 (7%) Query: 31 WAQYRQGEARFLPKDLDPSLCTHLIYAFAGMT--NHQLSTTEWNDETLYQEFNGLKKMNP 88 W Y + F P ++ L THL YAFA + ++ +++T ++++NP Sbjct: 10 WPAY--SVSEFPPSKINSRLFTHLYYAFAELNAPTFEVRVPPGSEKTAEDFTPTVRRLNP 67 Query: 89 KLKTLLAIGGWNFGT-QKFTDMVATANNRQTFVNSAIRFLRKYSFDGLDLDWEYPGSQGS 147 +KTL++IGG F + + A+ RQ FV S+I R+Y F GLDLD+EYP Sbjct: 68 SVKTLISIGGGGSEVRDNFAKLNSDASARQRFVKSSIALARRYGFHGLDLDYEYPE---- 123 Query: 148 PAVDKERFTTLVQDLANAFQQEAQTSGKERLLLSAAVPAGQT----YVDAGYEVDKIAQN 203 P ++ E F LV +L A ++EA+TSGK RLLL+ AV Q V Y V IA Sbjct: 124 PQLEMENFVKLVSELTAAIREEARTSGKPRLLLTEAVYFHQKLFPWEVVTEYPVQFIAAG 183 Query: 204 LDFVNLMAYDFHGSWEKVTGHNSPLYKRQEESGAAASLNVDAAVQQWLQKGTPASKLILG 263 LD+VN+MAYDFHGSWE TG + L + ++ +L G P KL+LG Sbjct: 184 LDWVNVMAYDFHGSWENFTGAPAAL------RDPNSKFTASVGIESFLAAGMPPEKLVLG 237 Query: 264 MPTYGRSFTLASSSDTRVGAPATGSGTPGPFTKEGGMLAYYEVCSWK--GATKQRIQDQK 321 +P +GRS+ L ++++ +GAPA G+G G L++ E+ ++ GA + Sbjct: 238 IPLFGRSWLLKNNNEVGIGAPAVGAGPV------DGALSFSEIQNFIRGGAREVFDTTTV 291 Query: 322 VPYIFRDNQWVGFDDVESFKTKVSYLKQKGLGGAMVWALDLD 363 Y ++DN WVG+D+ +S KV Y K+K LGG W+++ D Sbjct: 292 SAYAYKDNVWVGYDNQQSVALKVQYAKEKRLGGYFFWSVNQD 333 >3ALF-A nrPDB Length = 353 Score = 331 bits (848), Expect = 4e-91, Method: Composition-based stats. Identities = 107/345 (31%), Positives = 173/345 (50%), Gaps = 19/345 (5%) Query: 32 AQYRQGEARFLPKDLDPSLCTHLIYAFAGMTN--HQLSTTEWNDETLYQEFNGLKKMNPK 89 Y ++ ++D +L THL AFA + +QL + N ++ Q + +++ NP Sbjct: 6 GGYWFKDSGLALNNIDSTLFTHLFCAFADLNPQLNQLIISPENQDSFRQFTSTVQRKNPS 65 Query: 90 LKTLLAIGGWNFGTQKFTDMVATANNRQTFVNSAIRFLRKYSFDGLDLDWEYPGSQGSPA 149 +KT L+I G + + M N+R++F++S+IR R+ F GLDLDWEYP S A Sbjct: 66 VKTFLSIAGGRANSTAYGIMARQPNSRKSFIDSSIRLARQLGFHGLDLDWEYPLS----A 121 Query: 150 VDKERFTTLVQDLANAFQQEAQTSGKERLLLSAAVPAGQTYVDAGYEVDKIAQNLDFVNL 209 D TL+ + A EA+ SG+ LLL+AAV Y V+ +A+NLD++NL Sbjct: 122 ADMTNLGTLLNEWRTAINTEARNSGRAALLLTAAVSNSPRVNGLNYPVESLARNLDWINL 181 Query: 210 MAYDFHGS-WE-KVTGHNSPLYKRQEESGAAASLNVDAAVQQWLQKGTPASKLILGMPTY 267 MAYDF+G W T ++ L+ ++ + W+Q G P KL+LG+P Y Sbjct: 182 MAYDFYGPNWSPSQTNSHAQLFDP------VNHVSGSDGINAWIQAGVPTKKLVLGIPFY 235 Query: 268 GRSFTLASSSDTRVGAPATGSGTPGPFTKEGGMLAYYEVCSWK---GATKQRIQDQKVPY 324 G ++ L +++ + APA G G + G + Y + + AT Y Sbjct: 236 GYAWRLVNANIHGLRAPAAGKSNVG--AVDDGSMTYNRIRDYIVESRATTVYNATIVGDY 293 Query: 325 IFRDNQWVGFDDVESFKTKVSYLKQKGLGGAMVWALDLDDFAGFS 369 + + W+ +DD ++ + KV+Y+K +GL G W + D G S Sbjct: 294 CYSGSNWISYDDTQTVRNKVNYVKGRGLLGYFAWHVAGDQNWGLS 338 >6EPB-A nrPDB Length = 423 Score = 330 bits (847), Expect = 7e-91, Method: Composition-based stats. Identities = 117/366 (31%), Positives = 173/366 (47%), Gaps = 40/366 (10%) Query: 20 SAAKLVCYFTNWAQYRQGEARFLPKDLDPSLCTHLIYAFAGMT--------------NHQ 65 + YFTNW Y + F P DL S TH+IY+F + Sbjct: 36 NGYANSVYFTNWGIYDR---NFQPADLVASDVTHVIYSFMNLQADGTVISGDTYADYEKH 92 Query: 66 LSTTEWNDETL-----YQEFNGLKKMNPKLKTLLAIGGWNFGTQKFTDMVATANNRQTFV 120 + WND ++ +KK N LK LL+IGGW + T F +T NR+ F Sbjct: 93 YADDSWNDVGTNAYGCVKQLFKVKKANRGLKVLLSIGGWTWSTN-FPSAASTDANRKNFA 151 Query: 121 NSAIRFLRKYSFDGLDLDWEYPGSQGSPAVDKERFTTLVQDLANAFQQEA-QTSGKERLL 179 +AI F++ + FDG+D+DWEYP + A L++++ + A Q + L Sbjct: 152 KTAITFMKDWGFDGIDIDWEYP----ADATQASNMILLLKEVRSQLDAYAAQYAPGYHFL 207 Query: 180 LSAAVPAGQTYVDAGYEVDKIAQNLDFVNLMAYDFHGSWEKVTGHNSPLYKRQEESGAAA 239 L+ A PAG+ + + + Q LD++NLMAYD+ GS+ +TGH++ L+ A Sbjct: 208 LTIAAPAGKDNY-SKLRLADLGQVLDYINLMAYDYAGSFSPLTGHDANLFNNPSNPNA-T 265 Query: 240 SLNVDAAVQQWLQKGTPASKLILGMPTYGRSFTLASSSDTRVGAPATGSGTPGPFTKEGG 299 N D+AV+ ++ G PA+K++LGMP YGRSF + +GS E G Sbjct: 266 PFNTDSAVKDYINGGVPANKIVLGMPIYGRSFQNTAGIGQTYNGVGSGS-------WEAG 318 Query: 300 MLAYYEVCSWKGATKQRIQDQKVPYIFR--DNQWVGFDDVESFKTKVSYLKQKGLGGAMV 357 + Y + GAT Q K Y + + + FD + TKV+YLK GLGG+M Sbjct: 319 IWDYKAL-PKAGATVQYDSVAKGYYSYNSATKELISFDTPDMINTKVAYLKSLGLGGSMF 377 Query: 358 WALDLD 363 W D Sbjct: 378 WEASAD 383 >1LL6-A nrPDB Length = 392 Score = 326 bits (836), Expect = 1e-89, Method: Composition-based stats. Identities = 112/389 (28%), Positives = 183/389 (47%), Gaps = 47/389 (12%) Query: 21 AAKLVCYFTNWAQYRQGEARFLPKDLDPSLCTHLIYAFAGM--------------TNHQL 66 + V YF NWA Y +G P+DL TH++YAFA + T+ Sbjct: 2 GFRSVVYFVNWAIYGRGH---NPQDLKADQFTHILYAFANIRPSGEVYLSDTWADTDKHY 58 Query: 67 STTEWNDETLY-----QEFNGLKKMNPKLKTLLAIGGWNFGTQKFTDMVATANNRQTFVN 121 +W++ ++ LKK N LKTLL+IGGW + + F +T R+ F + Sbjct: 59 PGDKWDEPGNNVYGCIKQMYLLKKNNRNLKTLLSIGGWTY-SPNFKTPASTEEGRKKFAD 117 Query: 122 SAIRFLRKYSFDGLDLDWEYPGSQGSPAVDKERFTTLVQDLANAFQQE-AQTSGKERLLL 180 ++++ ++ FDG+D++WEYP + F L++ A A+ ++ LL Sbjct: 118 TSLKLMKDLGFDGIDINWEYPEDEKQ----ANDFVLLLKACREALDAYSAKHPNGKKFLL 173 Query: 181 SAAVPAGQTYVDAGYEVDKIAQNLDFVNLMAYDFHGSWEKVTGHNSPLYKRQEESGAAAS 240 + A PAG + ++ ++ + LDF NLMAYDF GSW+KV+GH S ++ + + Sbjct: 174 TIASPAGPQNYNK-LKLAEMDKYLDFWNLMAYDFSGSWDKVSGHMSNVFPSTTKP-ESTP 231 Query: 241 LNVDAAVQQWLQKGTPASKLILGMPTYGRSFTLASSSDTRVGAPATGSGTPGPFTKEGGM 300 + D AV+ +++ G PA+K++LGMP YGR+F T GS E G+ Sbjct: 232 FSSDKAVKDYIKAGVPANKIVLGMPLYGRAFASTDGIGTSFNGVGGGS-------WENGV 284 Query: 301 LAYYEVCSWKGATKQRIQDQKVPYIFRDNQ--WVGFDDVESFKTKVSYLKQKGLGGAMVW 358 Y ++ +GA ++D Y + N+ + +D V+ K Y+ + G+GG M W Sbjct: 285 WDYKDM-PQQGAQVTELEDIAASYSYDKNKRYLISYDTVKIAGKKAEYITKNGMGGGMWW 343 Query: 359 ALDLDDFAGFSCNQGRYPLIQTLRQELSL 387 D G L+ T+ L Sbjct: 344 ESSSD-------KTGNESLVGTVVNGLGG 365 >5GQB-A nrPDB Length = 553 Score = 317 bits (813), Expect = 5e-87, Method: Composition-based stats. Identities = 99/399 (24%), Positives = 162/399 (40%), Gaps = 68/399 (17%) Query: 23 KLVC-YFTNWAQYRQGEARFLPKDLDPSLCTHLIYAF----------------------- 58 K+V YF W Y +F + THL+Y F Sbjct: 151 KVVGAYFVEWGVY---PRKFPVDRVPIPNLTHLLYGFIPICGGDGINDSLKEIEGSFQAL 207 Query: 59 ------------------AGMTNHQLSTTEWND--ETLYQEFNGLKKMNPKLKTLLAIGG 98 A + Q + WN+ + + + LK+ P LK L +IGG Sbjct: 208 QRSCSGREDFKVSIHDPWAALQKPQKGLSSWNEPYKGNFGQLMMLKQAKPDLKILPSIGG 267 Query: 99 WNFGTQKFTDMVATANNRQTFVNSAIRFLRKYSF-DGLDLDWEYPGSQG-----SPAVDK 152 W F R+ FV S FL+ + F DG+D+DWE+PG +G D Sbjct: 268 WTLADPFF--FFTDETKRRRFVASVKDFLQTWKFFDGVDIDWEFPGGKGANPNLGSPKDG 325 Query: 153 ERFTTLVQDLANAFQQEAQTSGKERLLLSAAVPAGQTYVDAGYEVDKIAQNLDFVNLMAY 212 E + L+++L + + +G+ + L++A+ AG + + + +D + M+Y Sbjct: 326 EIYVLLMKELREMLNELSAETGR-KYELTSAISAGWDKIQV-VDYSAAQKYMDHIFFMSY 383 Query: 213 DFHGSWEKVT-GHNSPLYKRQEESGAAASLNVDAAVQQWLQKGTPASKLILGMPTYGRSF 271 DF G+W T GH + LY + + D VQ L +G K+++G+ YGR + Sbjct: 384 DFKGAWSNDTLGHQASLYAP--DWNEKETYTTDFGVQFLLAQGVSPKKIVVGVAMYGRGW 441 Query: 272 TLASSSDTRVGAPATGSGT-PGPFTKEGGMLAYYEVCSWKG---ATKQRIQDQKVPYIFR 327 T + P TG+ T P T + G++ Y E+ + + + PY+FR Sbjct: 442 TGV--HGYKDNNPFTGNATGPVKGTWQDGVVDYREIATEIAQGKWEYHYDKVAQAPYVFR 499 Query: 328 --DNQWVGFDDVESFKTKVSYLKQKGLGGAMVWALDLDD 364 + +DD S K Y++ LGG W +D D+ Sbjct: 500 PATGDLITYDDARSTIEKGKYVRANKLGGLFAWEIDADN 538 >5ZL9-A nrPDB Length = 618 Score = 313 bits (801), Expect = 1e-85, Method: Composition-based stats. Identities = 104/400 (26%), Positives = 166/400 (41%), Gaps = 68/400 (17%) Query: 23 KLVC-YFTNWAQYRQGEARFLPKDLDPSLCTHLIYAF----------------------- 58 K+V YF W Y + F + THL+Y F Sbjct: 135 KVVGSYFVEWGVYGR---NFTVDKIPAQNLTHLLYGFIPICGGNGINDSLKEIEGSFQAL 191 Query: 59 ------------------AGMTNHQLSTTEWND--ETLYQEFNGLKKMNPKLKTLLAIGG 98 A + Q T W+D + + + LK+ +P LK L +IGG Sbjct: 192 QRSCQGREDFKVSIHDPFAALQKAQKGVTAWDDPYKGNFGQLMALKQAHPDLKILPSIGG 251 Query: 99 WNFGTQKFTDMVATANNRQTFVNSAIRFLRKYSF-DGLDLDWEYPGSQG-----SPAVDK 152 W F + R FV S FL+ + F DG+D+DWE+PG +G D Sbjct: 252 WTLSDPFF--FMGDKVKRDRFVGSVKEFLQTWKFFDGVDIDWEFPGGKGANPNLGSPQDG 309 Query: 153 ERFTTLVQDLANAFQQEAQTSGKERLLLSAAVPAGQTYVDAGYEVDKIAQN-LDFVNLMA 211 E + L+++L Q + +G+ + L++A+ AG+ +D Y +AQN +D + LM+ Sbjct: 310 ETYVLLMKELRAMLDQLSVETGR-KYELTSAISAGKDKIDKFYSFVNVAQNSMDHIFLMS 368 Query: 212 YDFHGSWE-KVTGHNSPLYKRQEESGAAASLNVDAAVQQWLQKGTPASKLILGMPTYGRS 270 YDF+G+++ K GH + L + + V L +G K+++G YGR Sbjct: 369 YDFYGAFDLKNLGHQTALNAPAWKPD--TAYTTVNGVNALLAQGVKPGKIVVGTAMYGRG 426 Query: 271 FTLASSSDTRVGAPATGSGT-PGPFTKEGGMLAYYEVCSW---KGATKQRIQDQKVPYIF 326 +T + P TG+ T P T E G++ Y ++ + PY+F Sbjct: 427 WTGVNGYQN--NIPFTGTATGPVKGTWENGIVDYRQIAGQFMSGEWQYTYDATAEAPYVF 484 Query: 327 R--DNQWVGFDDVESFKTKVSYLKQKGLGGAMVWALDLDD 364 + + FDD S + K Y+ K LGG W +D D+ Sbjct: 485 KPSTGDLITFDDARSVQAKGKYVLDKQLGGLFSWEIDADN 524 >3QOK-A nrPDB Length = 420 Score = 308 bits (790), Expect = 2e-84, Method: Composition-based stats. Identities = 109/390 (27%), Positives = 163/390 (41%), Gaps = 64/390 (16%) Query: 25 VCYFTNWAQYRQGEARFLPKDLDPSLCTHLIYAFAGMTNHQLSTTE------------WN 72 V YF G + K LD THL Y+F + N + T W Sbjct: 29 VGYFNGGGDVTAGPGGDIDK-LDVRQITHLNYSFGLIYNDEKDETNAALKDPAHLHEIWL 87 Query: 73 DETL---YQEFNGLKKMNPKLKTLLAIGGWNFGTQKFTDMVATANNRQTFVNSAIRFLRK 129 + Q+ L+K NP LK LL++GGW G + F+ ATA +R F+ SA + +++ Sbjct: 88 SPKVQADLQKLPALRKQNPDLKVLLSVGGW--GARGFSGAAATAESRAVFIRSAQKIIQQ 145 Query: 130 YSFDGLDLDWEYP-----GSQGSPAVDKERFTTLVQDLANAFQQEAQTSGKERLLLSAAV 184 Y DG+DLDWE+P G S D++ FT L++ L A E+ L++ AV Sbjct: 146 YGLDGIDLDWEFPVNGAWGLVASQPADRDNFTALLKSLREAV--------GEQKLVTIAV 197 Query: 185 PAGQTYVDAGYEVDKIAQNLDFVNLMAYDFHGSWEKVTGHNSPLYKRQEES--GAAASLN 242 A + +V +A L+++NLM YD + NS LY AA + Sbjct: 198 GANAESPKSWVDVKAVAPVLNYINLMTYDMAYGTQYF---NSNLYDSSHWPTVAAADKYS 254 Query: 243 VDAAVQQWLQKGTPASKLILGMPTYGR----------SFTLASSSDTRVGAPATGSGTPG 292 D V +L G S++ LG+ YGR +T A + + V P G Sbjct: 255 ADFVVNNYLAAGLKPSQMNLGIGFYGRVPKRAVEPGIDWTKADAQNNPVTQPYFGPQQIA 314 Query: 293 PFTKEGGMLA------YYEVCSW------KGATKQRIQDQKVPYIFRDNQ------WVGF 334 F G L+ Y ++ K T+ + KVP++ + + + Sbjct: 315 LFASLGYDLSKDTYVKYNDIVGKLLNDPQKRFTEHWDDEAKVPWLSVQSAEGKPLFALSY 374 Query: 335 DDVESFKTKVSYLKQKGLGGAMVWALDLDD 364 ++ S K Y+K KGL GAM W DD Sbjct: 375 ENPRSVAIKADYIKAKGLAGAMFWEYGADD 404 >6F8N-A nrPDB Length = 414 Score = 308 bits (788), Expect = 4e-84, Method: Composition-based stats. Identities = 107/397 (26%), Positives = 163/397 (41%), Gaps = 64/397 (16%) Query: 20 SAAKLVCYFTNWAQYRQGEARFLPKDLDPSLCTHLIYAFAGMTNHQLSTTE---WNDETL 76 ++ V YF G + K LD + THL Y+F + N + T + L Sbjct: 9 ASYLSVGYFNGGGDVTAGPGGDINK-LDVTQITHLNYSFGLIYNDEKQETNPALKDPSRL 67 Query: 77 YQE------------FNGLKKMNPKLKTLLAIGGWNFGTQKFTDMVATANNRQTFVNSAI 124 +Q L+K NP+LK LL++GGW G + F+ ATA +R F+ S Sbjct: 68 HQIYLSPKVMADLQLLPVLRKQNPELKVLLSVGGW--GARGFSGAAATAESRAVFIRSVQ 125 Query: 125 RFLRKYSFDGLDLDWEYP-----GSQGSPAVDKERFTTLVQDLANAFQQEAQTSGKERLL 179 + +++Y DG+DLDW+YP G S D+ FT L+ +L A + L Sbjct: 126 QVIKQYHLDGIDLDWQYPVNGAWGLVESQPADRANFTLLLAELHKALDKGK--------L 177 Query: 180 LSAAVPAGQTYVDAGYEVDKIAQNLDFVNLMAYDFHGSWEKVTGHNSPLYKRQEES--GA 237 L+ AV A +V IA LD++NLM YD + NS LY ++ A Sbjct: 178 LTIAVGANVKSPQEWVDVKGIAPYLDYINLMTYDMAYGTQYF---NSNLYDSKQWPTVAA 234 Query: 238 AASLNVDAAVQQWLQKGTPASKLILGMPTYGR----------SFTLASSSDTRVGAPATG 287 A + + V +L G ++L LG+ YGR + A ++ V P Sbjct: 235 ADRYSANFVVDNYLAAGLKPAQLNLGIGFYGRVPKRATEPGIDWDKADAAKNPVTQPYFT 294 Query: 288 SGTPGPFT------KEGGMLAYYEVCSW------KGATKQRIQDQKVPYIFRDNQ----- 330 + F + Y ++ S + T D +VPY+ + Sbjct: 295 ARETAVFKAMGLDLTKDSYFKYNDIVSKLLNDPQRRFTAHWDSDAQVPYLTMKSAEGKPL 354 Query: 331 -WVGFDDVESFKTKVSYLKQKGLGGAMVWALDLDDFA 366 + +++ S K Y+K KGLGGAM W DD Sbjct: 355 FAISYENPRSVALKADYIKSKGLGGAMFWEYGADDNN 391 >3ARQ-A nrPDB Length = 584 Score = 301 bits (771), Expect = 4e-82, Method: Composition-based stats. Identities = 101/449 (22%), Positives = 171/449 (38%), Gaps = 99/449 (22%) Query: 27 YFTNWAQYRQGEARFLPKDLDPSLCTHLIYAFA-------------------------GM 61 YF W Y + + ++ TH++Y F G+ Sbjct: 143 YFVEWGIYGRD---YTVDNMPVDNLTHILYGFIPICGPNESVKSVGGNSFNALQTACRGV 199 Query: 62 TNHQLST-TEWND----------------ETLYQEFNGLKKMNPKLKTLLAIGGWNFGTQ 104 ++++ W + Y LK+ NP LK + +IGGW + Sbjct: 200 NDYEVVIHDPWAAYQKSFPQAGHEYSTPIKGNYAMLMALKQRNPDLKIIPSIGGWTL-SD 258 Query: 105 KFTDMVATANNRQTFVNSAIRFLRKYSF-DGLDLDWEYPG------SQGSPAVDKERFTT 157 F D V NR TFV S +FL+ + F DG+D+DWE+PG +G P D + Sbjct: 259 PFYDFV-DKKNRDTFVASVKKFLKTWKFYDGVDIDWEFPGGGGAAADKGDPVNDGPAYIA 317 Query: 158 LVQDLANAFQQEAQTSGKERLLLSAAVPAGQTYVDAGYEVDKIAQNLDFVNLMAYDFHGS 217 L+++L + +G+ L++A+ G ++ + Q +D++ M YDF+G Sbjct: 318 LMRELRVMLDELEAETGRT-YELTSAIGVGYDKIE-DVDYADAVQYMDYIFAMTYDFYGG 375 Query: 218 WEKVTGHNSPLY---------------KRQEESGAAASLNVDAAVQQWLQKGTPASKLIL 262 W V GH + LY E + D +Q L +G PA+KL+L Sbjct: 376 WNNVPGHQTALYCGSFMRPGQCDGGGVDENGEPYKGPAYTADNGIQLLLAQGVPANKLVL 435 Query: 263 GMPTYGRSFTLASSSD-TRVGAPATGS------GTPGPFTKEGGMLAYYEVCSW------ 309 G YGR + + T P TG+ G+ E G++ Y + S+ Sbjct: 436 GTAMYGRGWEGVTPDTLTDPNDPMTGTATGKLKGSTAQGVWEDGVIDYKGIKSFMLGANN 495 Query: 310 ---KGATKQRIQDQKVPYIFR--DNQWVGFDDVESFKTKVSYLKQKGLGGAMVWALDLDD 364 G + P+++ + + FDD S K +Y K GL G W +D D+ Sbjct: 496 TGINGFEYGYDAQAEAPWVWNRSTGELITFDDHRSVLAKGNYAKSLGLAGLFSWEIDADN 555 Query: 365 FAGFSCNQGRYPLIQTLRQELSLPYLPSG 393 ++ + + ++ + Sbjct: 556 GD----------ILNAMHEGMAGGVVTPP 574 >5DF0-A nrPDB Length = 545 Score = 299 bits (765), Expect = 2e-81, Method: Composition-based stats. Identities = 94/395 (23%), Positives = 160/395 (40%), Gaps = 64/395 (16%) Query: 24 LVCYFTNWAQYRQGEARFLPKDLDPSLCTHLIYAF------------------------- 58 + YF W Y + F + +HL+Y F Sbjct: 150 VAAYFVEWGVYGR---NFPVDKVPLPNLSHLLYGFIPICGGDGINDALKTISGSFESLQR 206 Query: 59 ----------------AGMTNHQLSTTEWND--ETLYQEFNGLKKMNPKLKTLLAIGGWN 100 A + Q S + WN+ + + + K NP LK L +IGGW Sbjct: 207 SCKGREDFKVAIHDPWAAVQKPQKSVSAWNEPYKGNFGQLMAAKLANPHLKILPSIGGWT 266 Query: 101 FGTQKFTDMVATANNRQTFVNSAIRFLRKYSF-DGLDLDWEYPGSQGSPAV------DKE 153 + + R FV+S FL+ + F DG+D+DWE+PG +G+ D + Sbjct: 267 LSDPFY--FMHDVEKRNVFVDSVKEFLQVWKFFDGVDVDWEFPGGKGANPSLGDAERDAK 324 Query: 154 RFTTLVQDLANAFQQEAQTSGKERLLLSAAVPAGQTYVDAGYEVDKIAQNLDFVNLMAYD 213 + L+++L +G+ L++A+ AG + A + ++L + LM+YD Sbjct: 325 TYILLLEELRAMLDDLEAQTGRV-YELTSAISAGYDKI-AVVNYAEAQKSLGKIFLMSYD 382 Query: 214 FHGSWEKV-TGHNSPLYKRQEESGAAASLNVDAAVQQWLQKGTPASKLILGMPTYGRSFT 272 F G+W G+ + +Y S AV L++G +K+I+G+ YGR +T Sbjct: 383 FKGAWSNTDLGYQTTVYAPSWNSEEL--YTTHYAVDALLKQGVDPNKIIVGVAMYGRGWT 440 Query: 273 LASSSDTRVGAPATGSGTPGPFTKEGGMLAYYEV-CSWKGATKQRIQDQKVPYIFRDNQ- 330 ++ TG+G P T E G++ Y ++ + Y+F ++ Sbjct: 441 GVTNYTNDNYFSGTGNG-PVSGTWEDGVVDYRQIQKDLNNYVYTFDSAAQASYVFDKSKG 499 Query: 331 -WVGFDDVESFKTKVSYLKQKGLGGAMVWALDLDD 364 + FD V+S KV Y+ + LGG W +D D+ Sbjct: 500 DLISFDSVDSVLGKVKYVDRNKLGGLFAWEIDADN 534 >4URI-A nrPDB Length = 337 Score = 299 bits (765), Expect = 2e-81, Method: Composition-based stats. Identities = 111/345 (32%), Positives = 172/345 (49%), Gaps = 27/345 (7%) Query: 32 AQYRQGEARFLPKDLDPSLCTHLIYAFAGM--TNHQLSTTEWNDETLYQEFNGLKKMNPK 89 Y + D++PS THL AFA + ++L+ + N ++ NP Sbjct: 4 GGYWYSGSGLAVSDINPSHFTHLFCAFADLDPNTNKLTISSSNAAAFSTFTQTVRAKNPS 63 Query: 90 LKTLLAIGGWNFGT--QKFTDMVATANNRQTFVNSAIRFLRKYSFDGLDLDWEYPGSQGS 147 +KTLL+IGG F +M + A+ R++F++S+I+ R+ +F GLDLDWEYP S Sbjct: 64 VKTLLSIGGGGGRALAAVFANMASQASRRKSFIDSSIQLARRNNFHGLDLDWEYP----S 119 Query: 148 PAVDKERFTTLVQDLANAFQQEAQTSGKERLLLSAAVPAG-QTYVDAGYEVDKIAQNLDF 206 +DK F +L+++ A E+ TSG LLLSAAV Q Y + IA NLD+ Sbjct: 120 SDIDKTNFASLIREWRAAVATESSTSGTPALLLSAAVGGSDQITPLKYYPGEAIANNLDW 179 Query: 207 VNLMAYDFHGS--WEKVTGHNSPLYKRQEESGAAASLNVDAAVQQWLQKGTPASKLILGM 264 VN+M YD + S + +T +PL+ + + D + +W+Q G P SKL LG+ Sbjct: 180 VNVMTYDLYTSDSYPTLTQPPAPLFYPRG------IFSADEGITKWIQSGVPESKLALGL 233 Query: 265 PTYGRSFTLASSSDTRVGAPATGSGTPGPFTKEGGMLAYYEVCSWKGATKQRIQDQKVPY 324 P YG + L+ ++ + APA T+ G + Y ++ + G + Y Sbjct: 234 PFYGFKWRLSDPNNHGLFAPA---------TQGLGAVKYKDIVN-TGGQVEFDSTYVTNY 283 Query: 325 IFRDNQWVGFDDVESFKTKVSYLKQKGLGGAMVWALDLDDFAGFS 369 F+ W G+DD +S KV+Y KQ+GL G W ++ D S Sbjct: 284 RFKGTDWYGYDDTQSISAKVAYAKQRGLFGYFAWHIEQDSNWALS 328 >5Z7M-A nrPDB Length = 546 Score = 298 bits (764), Expect = 3e-81, Method: Composition-based stats. Identities = 100/400 (25%), Positives = 162/400 (40%), Gaps = 70/400 (17%) Query: 23 KLVC-YFTNWAQYRQGEARFLPKDLDPSLCTHLIYAF----------------------- 58 K+V YF W Y + F + THL+Y F Sbjct: 135 KVVGSYFVEWGVYGR---NFTVDKIPAQNLTHLLYGFIPICGGNGINDSLKEIEGSFQAL 191 Query: 59 ------------------AGMTNHQLSTTEWND--ETLYQEFNGLKKMNPKLKTLLAIGG 98 A + Q T W+D + + + LK+ +P LK L +IGG Sbjct: 192 QRSCQGREDFKVSIHDPFAALQKAQKGVTAWDDPYKGNFGQLMALKQAHPDLKILPSIGG 251 Query: 99 WNFGTQKFTDMVATANNRQTFVNSAIRFLRKYSF-DGLDLDWEYPGSQG-----SPAVDK 152 W F + R FV S FL+ + F DG+D+ WE+PG +G D Sbjct: 252 WTLSDPFF--FMGDKVKRDRFVGSVKEFLQTWKFFDGVDIAWEFPGGKGANPNLGSPQDG 309 Query: 153 ERFTTLVQDLANAFQQEAQTSGKERLLLSAAVPAGQTYVDA-GYEVDKIAQNLDFVNLMA 211 E + L+++L Q + +G+ + L++A+ AG+ +D Y V + ++D + LM+ Sbjct: 310 ETYVLLMKELRAMLDQLSVETGR-KYELTSAISAGKDMIDKVAYNVAQ--NSMDHIFLMS 366 Query: 212 YDFHGSWE-KVTGHNSPLYKRQEESGAAASLNVDAAVQQWLQKGTPASKLILGMPTYGRS 270 YDF+G+ + K GH + L + + V L +G K+++G YGR Sbjct: 367 YDFYGAADLKNLGHQTALNAPAWKPD--TAYTTVNGVNALLAQGVKPGKIVVGTAMYGRG 424 Query: 271 FTLASSSDTRVGAPATGSGT-PGPFTKEGGMLAYYEVCSW---KGATKQRIQDQKVPYIF 326 +T + P TG+ T P T E G++ Y ++ + PY+F Sbjct: 425 WTGVNGYQN--NIPFTGTATGPVKGTWENGIVDYRQIAGQFMSGEWQYTYDATAEAPYVF 482 Query: 327 R--DNQWVGFDDVESFKTKVSYLKQKGLGGAMVWALDLDD 364 + + FDD S + K Y+ K LGG +D D+ Sbjct: 483 KPSTGDLITFDDARSVQAKGKYVLDKQLGGLFSAMIDADN 522 >1KFW-A nrPDB Length = 435 Score = 290 bits (741), Expect = 1e-78, Method: Composition-based stats. Identities = 108/414 (26%), Positives = 170/414 (41%), Gaps = 82/414 (19%) Query: 20 SAAKLVCYFTNWAQYRQGEARFLPKDLDPSL----CTHLIYAFAGMTNHQLST------- 68 + + V YF W Y + F K LD S TH+ Y+F + N L+ Sbjct: 7 NGYRNVGYFAQWGVYGRA---FQAKQLDVSGTAKNLTHINYSFGNINNQTLTCFMANKAQ 63 Query: 69 -------------------------------TEWNDE--TLYQEFNGLKKMNPKLKTLLA 95 W+ + + LK NPKLK +++ Sbjct: 64 GTGPNGSDGAGDAWADFGMGYAADKSVSGKADTWDQPLAGSFNQLKQLKAKNPKLKVMIS 123 Query: 96 IGGWNFGTQKFTDMVATANNRQTFVNSAIRFLRKYS----------------FDGLDLDW 139 +GGW + ++ F+ AT +RQ V+S I K + FDG+D+DW Sbjct: 124 LGGWTW-SKNFSKAAATEASRQKLVSSCIDLYIKGNLPNFEGRGGAGAAAGIFDGIDIDW 182 Query: 140 EYPGSQGSPA-------VDKERFTTLVQDLANAFQQEAQTSGKERLLLSAAVPAGQTYVD 192 E+PG+ A D+ F L+ + T+ K + +LSA +PA +D Sbjct: 183 EWPGTNSGLAGNGVDTVNDRANFKALLAEFRKQLDAYGSTNNK-KYVLSAFLPANPADID 241 Query: 193 AG-YEVDKIAQNLDFVNLMAYDFHGSWE-KVTGHNSPLYKRQEES-GAAASLNVDAAVQQ 249 AG ++ ++LDF ++ YD HG+W +TGH + LY + + + D AV++ Sbjct: 242 AGGWDDPANFKSLDFGSIQGYDLHGAWNPTLTGHQANLYDDPADPRAPSKKFSADKAVKK 301 Query: 250 WLQKGTPASKLILGMPTYGRSFTLASSSDTRVGAPATGSGTPGPFTKEGGMLAYYEVCSW 309 +L G +L LG+ YGR +T A + PAT P T E Y ++ + Sbjct: 302 YLAAGIDPKQLGLGLAAYGRGWTGAK--NVSPWGPATDGA---PGTYETANEDYDKLKTL 356 Query: 310 KGATKQRIQDQKVPYIFRDNQWVGFDDVESFKTKVSYLKQKGLGGAMVWALDLD 363 T + + QW +D++ + K K Y+ KGLGG M W L D Sbjct: 357 --GTDHYDAATGSAWRYDGTQWWSYDNIATTKQKTDYIVSKGLGGGMWWELSGD 408 >3WD0-A nrPDB Length = 503 Score = 286 bits (732), Expect = 1e-77, Method: Composition-based stats. Identities = 104/418 (24%), Positives = 175/418 (41%), Gaps = 74/418 (17%) Query: 20 SAAKLVCYF-------TNWAQYRQGEARFLPKDLDPSL---CTHLIYAFAGMTNH----- 64 + ++ Y+ N+ + F ++ P+ TH+ ++F + ++ Sbjct: 7 TRKAVIGYYFIPTNQINNYTETDTSVVPFPVSNITPAKAKQLTHINFSFLDINSNLECAW 66 Query: 65 QLSTTEWNDETLYQEFNGLKKMNPKLKTLLAIGGWNFGTQ------KFTDMVATANNRQT 118 +T + + LK NP L+ + +IGGW + + + V T R Sbjct: 67 DPATNDAKARDVVNRLTALKAHNPSLRIMFSIGGWYYSNDLGVSHANYVNAVKTPAARTK 126 Query: 119 FVNSAIRFLRKYSFDGLDLDWEYPGSQGSPAVDKERFTTLVQDLANAFQQEAQTSGKER- 177 F S +R ++ Y FDG+D+DWEYP A + + F +Q++ Q+ G++ Sbjct: 127 FAQSCVRIMKDYGFDGVDIDWEYP-----QAAEVDGFIAALQEIRTLLNQQTIADGRQAL 181 Query: 178 -LLLSAAVPAGQTYVDAGY-EVDKIAQNLDFVNLMAYDFHGSWEKVTGHNSPLYKRQEES 235 L+ A G ++ Y ++ +I LD++NLM YD G WEK+T H + L+ Sbjct: 182 PYQLTIAGAGGAFFLSRYYSKLAQIVAPLDYINLMTYDLAGPWEKITNHQAALFGDAAGP 241 Query: 236 GAAA----------------------SLNVDAAVQQWL-QKGTPASKLILGMPTYGRSFT 272 SL VDAAVQQ L +G P++K+++G+P YGR+F Sbjct: 242 TFYNALREANLGWSWEELTRAFPSPFSLTVDAAVQQHLMMEGVPSAKIVMGVPFYGRAFK 301 Query: 273 LASSSDTRVGAPATGSGTPGPFTKEGGMLAYYEVCSWK-------------------GAT 313 S + + + G P+ L + C G Sbjct: 302 GVSGGNGGQYSSHSTPGED-PYPNADYWLVGCDECVRDKDPRIASYRQLEQMLQGNYGYQ 360 Query: 314 KQRIQDQKVPYIF--RDNQWVGFDDVESFKTKVSYLKQKGLGGAMVWALDLDDFAGFS 369 + K PY++ ++ +V +DD ESFK K Y+KQ+ LGG M W L D+ G Sbjct: 361 RLWNDKTKTPYLYHAQNGLFVTYDDAESFKYKAKYIKQQQLGGVMFWHLGQDNRNGDL 418 >1JNE-A nrPDB Length = 420 Score = 285 bits (728), Expect = 4e-77, Method: Composition-based stats. Identities = 116/430 (26%), Positives = 196/430 (45%), Gaps = 75/430 (17%) Query: 21 AAKLVCYFTNWAQYRQGEARFLPKDLDPSL--CTHLIYAFAGMTNHQLSTTEWND----- 73 A+ LVCY+ + + R+G + L DL+ +L C+HL+Y +AG+ L N+ Sbjct: 1 ASNLVCYYDSSSYTREGLGKLLNPDLEIALQFCSHLVYGYAGLRGENLQAYSMNENLDIY 60 Query: 74 ETLYQEFNGLKKMNPKLKTLLAIGGWNF----GTQKFTDMVATANNRQT-FVNSAIRFLR 128 + + E LK+ P LK LL++GG + K+ D++ RQ F+ SA ++ Sbjct: 61 KHQFSEVTSLKRKYPHLKVLLSVGGDHDIDPDHPNKYIDLLEGEKVRQIGFIRSAYELVK 120 Query: 129 KYSFDGLDLDWEYPGSQG--------------------------SPAVDKERFTTLVQDL 162 Y FDGLDL +++P ++ A+ KE+FT LV+D+ Sbjct: 121 TYGFDGLDLAYQFPKNKPRKVHGDLGLAWKSIKKLFTGDFIVDPHAALHKEQFTALVRDV 180 Query: 163 ANAFQQEAQTSGKERLLLSAAVPAGQTYVDAGYEVDKIAQNLDFVNLMAYDFHGSWEK-- 220 ++ + + LLS V +++ + +DFVNL +DF Sbjct: 181 KDSLRADG-------FLLSLTVLPNVNS-TWYFDIPALNGLVDFVNLATFDFLTPARNPE 232 Query: 221 VTGHNSPLYKRQEESGAAASLNVDAAVQQWLQKGTPASKLILGMPTYGRSFTLASSSDTR 280 +++P+Y A LN D V+ WL +G P++K+ LG+ TYG ++ L S Sbjct: 233 EADYSAPIYHPDGSKDRLAHLNADFQVEYWLSQGFPSNKINLGVATYGNAWKLTKDSGLE 292 Query: 281 VGAP----ATGSGTPGPFTKEGGMLAYYEVCSW-----------KGATKQRIQDQK---- 321 G P +G G +++ G+L+Y E+C + +R+ D Sbjct: 293 -GVPVVPETSGPAPEGFQSQKPGLLSYAEICGKLSNPQNQFLKGNESPLRRVSDPTKRFG 351 Query: 322 -VPYIFRDNQ-----WVGFDDVESFKTKVSYLKQKGLGGAMVWALDLDDFAGFSCNQGRY 375 + Y D Q WV +DD +S K +Y + K LGG ++ L DDF G C+ +Y Sbjct: 352 GIAYRPVDGQITEGIWVSYDDPDSASNKAAYARVKNLGGVALFDLSYDDFRG-QCSGDKY 410 Query: 376 PLIQTLRQEL 385 P+++ ++ L Sbjct: 411 PILRAIKYRL 420 >4A5Q-A nrPDB Length = 546 Score = 266 bits (681), Expect = 1e-71, Method: Composition-based stats. Identities = 105/490 (21%), Positives = 185/490 (37%), Gaps = 124/490 (25%) Query: 22 AKLVCYFTNWAQYRQGEARFLPKDL----------------DPSLCTHLIYAFAG----- 60 ++CYFT+W+QY + R + K++ D LIY+F G Sbjct: 72 FNVLCYFTDWSQY---DPRIINKEIRDTGGRSADILRLNTPDGRPFKRLIYSFGGLIGDK 128 Query: 61 -----------------------MTNHQLST-----------------TEWND------- 73 + NH+ T T+W Sbjct: 129 KYSADGNASIAVRLGVATDPDDAIANHKGKTIPVDPDGAVLASINCGFTKWEAGDANERY 188 Query: 74 -----ETLYQEFNGLKKMNPKLKTLLAIGGWNFGTQKFTDMVATANNRQTFVNSAIRFLR 128 + L F L + + +L+ L+IGGW+ + F+++ R FV F + Sbjct: 189 NQEKAKGLLGGFRLLHEADKELEFSLSIGGWSM-SGLFSEIAKDEILRTNFVEGIKDFFQ 247 Query: 129 KYS-FDGLDLDWEYPGSQGS----PAVDKERFTTLVQDLANAFQQEAQTSGKERLLLSAA 183 ++ F LD+DWEYPGS G+ D F L+Q + +A + + G +S A Sbjct: 248 RFPMFSHLDIDWEYPGSIGAGNPNSPDDGANFAILIQQITDA--KISNLKG-----ISIA 300 Query: 184 VPAGQTYVDAGYEVDKIAQNLDFVNLMAYDFHGSWEKVTGHNSPLYKRQEESGAAASLNV 243 A +DA + + +NLM YDF + H++ +Y+ + + ++ Sbjct: 301 SSADPAKIDAANIPALMDAGVTGINLMTYDFFTLGDGKLSHHTNIYRDPSDV--YSKYSI 358 Query: 244 DAAVQQWLQ-KGTPASKLILGMPTYGRSFTLASSSDTRVGAPATGSGTPGPFTKEGGMLA 302 D AV + K + +G Y R+ A ++ P + G +T L Sbjct: 359 DDAVTHLIDEKKVDPKAIFIGYAGYTRN---AKNATITTSIP-SEEALKGTYTDANQTLG 414 Query: 303 YYE---------VCSW---------KGATKQRIQDQKVPYIFRD--NQWVGFDDVESFKT 342 +E +C + G + K Y++ + ++ D S + Sbjct: 415 SFEYSVLEWTDIICHYMDFEKGEGRNGYKLVHDKVAKADYLYSEATKVFISLDTPRSVRD 474 Query: 343 KVSYLKQKGLGGAMVWALDLDDFAGFSCNQGRYPLIQTLRQ---ELSLPYLPSGTPELEV 399 K Y+K KGLGG +W+ D D+ G N L + ++ +++ YL S + E+ Sbjct: 475 KGRYVKDKGLGGLFIWSGDQDN--GILTNAAHEGLKRRIKNKVIDMTPFYLDS---DEEL 529 Query: 400 PKPGQPSEPE 409 P +P+EP+ Sbjct: 530 PTYTEPAEPQ 539 >4W5U-B nrPDB Length = 408 Score = 266 bits (680), Expect = 2e-71, Method: Composition-based stats. Identities = 100/402 (24%), Positives = 154/402 (38%), Gaps = 77/402 (19%) Query: 25 VCYFTNWAQYRQGEARFLPKDLDPS----LCTHLIYAFAGMTNHQLST------------ 68 + YFT W Y + F K+LD S TH+ YAF +T + + Sbjct: 44 LGYFTEWGTYDR---NFNVKNLDTSGTAAKITHINYAFGNVTGGKCAIGDSYADYDKAFT 100 Query: 69 ---------TEWNDE--TLYQEFNGLKKMNPKLKTLLAIGGWNFGTQKFTDMVATANNRQ 117 W+ + + LK P +K L + GGW + + F D Q Sbjct: 101 ADQSVSGQADTWDQPLRGNFNQLRQLKAKYPHIKVLWSFGGWTW-SGGFADAAKDP---Q 156 Query: 118 TFVNSAIRFLRK----YSFDGLDLDWEYPGSQG--SPAVDKERFTTLVQDLANAFQQEAQ 171 F S + FDG+D+DWEYP + G + + F L+ L + F E Sbjct: 157 GFAQSCYNLVHDPRWDGVFDGIDIDWEYPNACGLTCDSSGPDAFRNLMAALRSTFGDE-- 214 Query: 172 TSGKERLLLSAAVPAG--QTYVDAGYEVDKIAQNLDFVNLMAYDFHGSWEKV--TGHNSP 227 L++AAV A + AQ +D+ N+M YDF G+W+ T +SP Sbjct: 215 -------LVTAAVTADGTPGGKIEATDYAGAAQYVDWYNVMTYDFFGAWDAQGPTAPHSP 267 Query: 228 LYKRQEESGAAASLNVDAAVQQWLQKGTPASKLILGMPTYGRSFTLASSSDTRVGAPATG 287 L + A+ + +G PA KL+LG+ YGR +T + AP Sbjct: 268 L--TSYDGIPKQGFTSADAIAAFKAQGVPADKLLLGIGFYGRGWTGVTQD-----APGGT 320 Query: 288 SGTPGPFTKEGGMLAYY---EVCSWKGATKQRIQDQKVPYIFRDNQWVGFDDVESFKTKV 344 + P T E G+ Y C G Y + +D ++ +K+ Sbjct: 321 ATGPAAGTWEQGIEDYKVLKNTCPVTGTV------AGTAYAHCGSNLWSYDTPDTIASKM 374 Query: 345 SYLKQKGLGGAMVWALDLDDFAGFSCNQGRYPLIQTLRQELS 386 ++ +GL GA W DF+G + + LI L L+ Sbjct: 375 AWANDQGLRGAFAW-----DFSGDTADG---ELIAALSNGLA 408 >4TXG-A nrPDB Length = 793 Score = 264 bits (675), Expect = 6e-71, Method: Composition-based stats. Identities = 117/499 (23%), Positives = 192/499 (38%), Gaps = 121/499 (24%) Query: 16 IPWGSAAKLVCYFTNWAQYRQGEARFLPKDLDPSLCTHLIYAFAGMTN-HQLSTTEWND- 73 + GS +++ YFT+W + G +L D+ S TH+ YAFA + ++LS E Sbjct: 148 LANGSRRRIIGYFTSWRTGKDGSPAYLASDIPWSKLTHINYAFAHVDGSNKLSVNETAPG 207 Query: 74 ----------------------ETLYQEFNGLKKMNPKLKTLLAIGGW------------ 99 + + K+ P +KTL+++GGW Sbjct: 208 NPATDMSWPGVAGAEMDASLPYKGHFNLLTQYKRKYPGVKTLISVGGWAETGGYFDANGK 267 Query: 100 NFGTQKFTDMVATANNR------QTFVNSAIRFLRKYSFDGLDLDWEYPGSQGSP----- 148 + F M A+ F +SA+ FLRKY FDG+D+D+EYP S + Sbjct: 268 RVASGGFYSMTVNADGTVNQAGINAFSDSAVAFLRKYGFDGVDIDFEYPTSMNNAGNPLD 327 Query: 149 --------AVDKERFTTLVQDLANAFQQEAQTSGKERLLLSAAVPAGQTYVDAGYEVDKI 200 + + L+Q L + + A G+ ++AAVPA Y+ G E + Sbjct: 328 WTFSNARLGSLNKGYVALLQTLRDRLDRAAAQDGR-YYQITAAVPAS-GYLLRGMETFQG 385 Query: 201 AQNLDFVNLMAYDFHGSWEKVTGHNSPLYKRQEES-------------GAAASLNVDAAV 247 + LDFVN+M+YD HG+W + G N+ LY +++ G LN D A Sbjct: 386 LKYLDFVNVMSYDLHGAWNRFVGPNAALYDDGKDAELAFWNVYSTPQYGNIGYLNTDWAY 445 Query: 248 QQWLQKGTPASKLILGMPTYGRSFTLASSSDTRVGAPATGSGTPGPFTK----------- 296 + + G PAS++ +G+P Y R + S + + GS P T+ Sbjct: 446 HYY-RGGLPASRVNMGVPYYTRGWKNVSGGSNGLWGSSVGSNCPAGLTECGDGAVGIDNI 504 Query: 297 ----------------------------EGGMLAYYEV-----CSWKGATKQRIQDQ--K 321 G LA Y + + + QR + Sbjct: 505 WHDLDDSGKEIPGGSNPMWHAKNLEKGLAGSYLAAYGIDPTLPINQLTGSYQRNYNGALA 564 Query: 322 VPYIFRDNQ--WVGFDDVESFKTKVSYLKQKGLGGAMVWAL--DLDDFAGFSCNQGRYPL 377 P+++ + ++ +D +S K +++ +GG M W L D D A + QG Y + Sbjct: 565 APWLWNAGKKVFLSTEDEQSIAQKAAWIDANNVGGVMFWELAGDYDWKAQRNNGQGEYFI 624 Query: 378 IQTLRQELSLPYLPSGTPE 396 TL L + Sbjct: 625 GTTLTSLLYNTFSQPPKVS 643 >4DWS-C nrPDB Length = 546 Score = 254 bits (650), Expect = 4e-68, Method: Composition-based stats. Identities = 81/312 (25%), Positives = 130/312 (41%), Gaps = 23/312 (7%) Query: 84 KKMNPKLKTLLAIGGWNFGTQKFTDMVATANNRQTFVNSAIRFLRKYS-FDGLDLDWEYP 142 M KL +IGGW+ + F+ + + R+ FV S + F ++ F +D+DWEYP Sbjct: 206 HAMGHKLDLAFSIGGWSLSS-YFSALAENPDERRVFVASVVDFFVRFPMFSCVDIDWEYP 264 Query: 143 GSQG-----SPAVDKERFTTLVQDLANAFQQEAQTSGKERLLLSAAVPAGQTYVDAGYEV 197 G G S D E + L+++L +A S ++ +S A + + Sbjct: 265 GGGGDEGNISSDKDGENYVLLIKELRSALDSRFGYSNRKE--ISIACSGVKAKLKKSNID 322 Query: 198 DKIAQNLDFVNLMAYDFHGS-WEKVTGHNSPLYKRQEESGAA-ASLNVDAAVQQWLQK-G 254 +A LD + LM+YDF G+ W GH++ LY ++ L+ +AA+ + G Sbjct: 323 QLVANGLDNIYLMSYDFFGTIWADYIGHHTNLYSPKDPGEQELFDLSAEAAIDYLHNELG 382 Query: 255 TPASKLILGMPTYGRSFTLAS--SSDTRVGAPATGS---GTPGPF-TKEGGMLAYYEVCS 308 P K+ LG YGRS + PA G+ G P F + M A + + Sbjct: 383 IPMEKIHLGYANYGRSAVGGDLTTRQYTKNGPALGTMENGAPEFFDIVKNYMDAEHSLSM 442 Query: 309 -WKGATKQRIQDQKVPYIFRD--NQWVGFDDVESFKTKVSYLKQKGLGGAMVWALDLDDF 365 G + ++F + ++ D + K K Y + LGG W+ D D Sbjct: 443 GKNGFVLMTDTNADADFLFSEAKGHFISLDTPRTVKQKGEYAAKNKLGGVFSWSGDQD-- 500 Query: 366 AGFSCNQGRYPL 377 G N R L Sbjct: 501 CGLLANAAREGL 512 >6OGD-C nrPDB Length = 633 Score = 253 bits (646), Expect = 1e-67, Method: Composition-based stats. Identities = 81/312 (25%), Positives = 130/312 (41%), Gaps = 23/312 (7%) Query: 84 KKMNPKLKTLLAIGGWNFGTQKFTDMVATANNRQTFVNSAIRFLRKYS-FDGLDLDWEYP 142 M KL +IGGW+ + F+ + + R+ FV S + F ++ F +D+DWEYP Sbjct: 293 HAMGHKLDLAFSIGGWSLSS-YFSALAENPDERRVFVASVVDFFVRFPMFSCVDIDWEYP 351 Query: 143 GSQG-----SPAVDKERFTTLVQDLANAFQQEAQTSGKERLLLSAAVPAGQTYVDAGYEV 197 G G S D E + L+++L +A S ++ +S A + + Sbjct: 352 GGGGDEGNISSDKDGENYVLLIKELRSALDSRFGYSNRKE--ISIACSGVKAKLKKSNID 409 Query: 198 DKIAQNLDFVNLMAYDFHGS-WEKVTGHNSPLYKRQEESGAA-ASLNVDAAVQQWLQK-G 254 +A LD + LM+YDF G+ W GH++ LY ++ L+ +AA+ + G Sbjct: 410 QLVANGLDNIYLMSYDFFGTIWADYIGHHTNLYSPKDPGEQELFDLSAEAAIDYLHNELG 469 Query: 255 TPASKLILGMPTYGRSFTLAS--SSDTRVGAPATGS---GTPGPF-TKEGGMLAYYEVCS 308 P K+ LG YGRS + PA G+ G P F + M A + + Sbjct: 470 IPMEKIHLGYANYGRSAVGGDLTTRQYTKNGPALGTMENGAPEFFDIVKNYMDAEHSLSM 529 Query: 309 -WKGATKQRIQDQKVPYIFRD--NQWVGFDDVESFKTKVSYLKQKGLGGAMVWALDLDDF 365 G + ++F + ++ D + K K Y + LGG W+ D D Sbjct: 530 GKNGFVLMTDTNADADFLFSEAKGHFISLDTPRTVKQKGEYAAKNKLGGVFSWSGDQD-- 587 Query: 366 AGFSCNQGRYPL 377 G N R L Sbjct: 588 CGLLANAAREGL 599 >5XWF-A nrPDB Length = 378 Score = 248 bits (634), Expect = 3e-66, Method: Composition-based stats. Identities = 107/388 (27%), Positives = 172/388 (44%), Gaps = 60/388 (15%) Query: 21 AAKLVCYFTNWAQYRQGEARFLPKDLDPSLCTHLIYAFAGMTNH-QLSTTEWND-ETLYQ 78 KL Y +W LPK + H++YAFA T +LS + +++ Q Sbjct: 1 GQKLSAYVVDW---------DLPKSIAWDKLDHIVYAFAEPTKDGELSGFTDSQLKSVVQ 51 Query: 79 EFNGLKKMNPKLKTLLAIGGWNFGTQKFTDMVATANNRQTFVNSAIRFLRKYSFDGLDLD 138 E + K L++GGW G+ F+D++ ++++ FV++ + +++Y DGL+LD Sbjct: 52 EAHSRGKS-----ISLSVGGWT-GSLYFSDLLKSSSSFDNFVSNLVDVVKEYDLDGLNLD 105 Query: 139 WEYPGSQGSPAV------DKERFTTLVQDLANAFQQEAQTSGKERLLLSAAVPAGQTYVD 192 WEYP S A D + L + L + +L+ AVP + Sbjct: 106 WEYPNSPNGVACNSKDENDTANYLKLFKALREKL--------GSKTILTTAVPTAPFNDE 157 Query: 193 AGYE----VDKIAQNLDFVNLMAYDFHGSWEKVTGHNSPLYKRQEESGAAASLNVDAAVQ 248 D A +D +MAYD +G +K G N+PLY + +G + + + AV+ Sbjct: 158 NQQPSTKLDDNWASTVDAFYIMAYDVNGIRDKNAGANAPLYYSPKVTGVEPT-SGNDAVK 216 Query: 249 QWLQKGTPASKLILGMPTYGR-SFTLAS-SSDTRVGAPATGSGT-PGPFTKE-------G 298 W+ G PA +L+LG+P YGR S TL ++ T + P + S G T E Sbjct: 217 AWIAAGIPAEQLVLGVPFYGRVSKTLEPITASTGLYVPISQSSQIKGDSTDEKAADPCPN 276 Query: 299 GMLAYYEVCSWK------------GATKQRIQDQKVPYIFR--DNQWVGFDDVESFKTKV 344 + Y W+ G K PY + ++ + FDD S + KV Sbjct: 277 AVATYSGQYIWRTIAQEGIARNSSGWVTYWDDISKTPYAYSFSGSKVLSFDDAASLQDKV 336 Query: 345 SYLKQKGLGGAMVWALDLDDFAGFSCNQ 372 Y K++GLGG M+W+L++DD N Sbjct: 337 DYAKKQGLGGVMLWSLEMDDDENTLLNA 364 >4WIW-A nrPDB Length = 349 Score = 169 bits (427), Expect = 3e-42, Method: Composition-based stats. Identities = 69/324 (21%), Positives = 132/324 (40%), Gaps = 48/324 (14%) Query: 71 WND-ETLYQEFNGLKKMNPKLKTLLAIGGWNFGTQKFTDMVATANNRQTFVNSAIRFLRK 129 W++ + Y++ + +K L I G ++ + R+ + + L+ Sbjct: 55 WDEGSSNYKQLTNM-AHGLGMKVLPLING---SGATLNTLLKSPAAREKLIGEIVVLLKN 110 Query: 130 YSFDGLDLDWEYPGSQGSPAVDKERFTTLVQDLANAFQQ-EAQTSGKERLLLSAAVP--- 185 + DG+ +D+E P G K+ + + DL + ++ +L++ A +P Sbjct: 111 TNADGVVIDFETPLDYGDV---KDPYDGVRNDLTAFMESLHSELQSMNKLVVMAVMPRMS 167 Query: 186 AGQTYVDAGYEVDKIAQNLDFVNLMAYDFHGSWEKVTGHNSPLYKRQEESGAAASLNVDA 245 + Q ++DA Y+ + ++ +D++++M YD H R G A Sbjct: 168 SSQYWLDA-YDYEALSHAVDYLHVMTYDHH--------------YRTSAPGPIAPYPWIK 212 Query: 246 AVQQWLQ-KGTPASKLILGMPTYGRSFTLASSSDTRVGAPATGSGTPGPFTKE------- 297 V ++Q +G SK+++G+P YGR + + G P S G ++K Sbjct: 213 QVLTYIQGQGVDMSKVLMGIPYYGRDWVVDGKDAN--GNPTYNSTAFG-YSKALELADSY 269 Query: 298 GGMLAY--YEVCSWKGATKQRIQDQKVPYIFRDNQWVGFDDVESFKTKVSYLKQKGLGGA 355 G + Y Y G + D+K V FDD S+ K+S + + GL G Sbjct: 270 GATITYSKYNDADPVGTPTFKYTDEK-----GVEHTVFFDDYTSWNAKLSIINEFGLAGV 324 Query: 356 MVWALDLDDFAGFSCNQGRYPLIQ 379 WA+ D + +G +PL+ Sbjct: 325 GPWAMGWVD---ENTAEGLFPLLN 345 >4Q6T-A nrPDB Length = 351 Score = 154 bits (389), Expect = 8e-38, Method: Composition-based stats. Identities = 53/278 (19%), Positives = 107/278 (38%), Gaps = 42/278 (15%) Query: 99 WNFGTQKFTDMVATANNRQTFVNSAIRFLRKYSFDGLDLDWEYPGSQGSPAVDKERFTTL 158 F ++ V ++ ++ F G++LD+E ++ F Sbjct: 81 GAFDPAISHSILNDRALSAGTVKQLVKLAKEGGFAGINLDFE-----KVEPRNRAAFCAF 135 Query: 159 VQDLANAFQQEAQTSGKERLLLSAAVPAGQTYVD--AGYEVDKIAQNLDFVNLMAYDFHG 216 V+ L NA ++L++S T + GY+ + +D+ +M YD G Sbjct: 136 VKTLGNALHA-----SNKKLIISIPPKLSDTEPEYLQGYDYKALGAAVDYFQVMTYDQVG 190 Query: 217 -SWEKVTGHNSPLYKRQEESGAAASLNVDAAVQQWLQKGTPASKLILGMPTYGRSFTLAS 275 W HN + G + + A+ + PASK++ G+PTYG+ +++ + Sbjct: 191 PGWSSGGFHN------EAWPGPESGFDWQQALLSYAVSRVPASKVLAGLPTYGQDYSIGN 244 Query: 276 SSD---------TRVGAPATGSGTPGPFTKEGGMLAYYEVCSWKGATKQRIQDQKVPYIF 326 A + + P+ G + ++ + + ++ P ++ Sbjct: 245 RVHWSAYQEIIAEHRAAIHRDAASATPYATWGPVKSFVD-------GVEWTPERAQPVLW 297 Query: 327 RDNQWVGFDDVESFKTKVSYLKQKGLGGAMVWALDLDD 364 +DD S KTK + + + GLGG VWA+ ++ Sbjct: 298 -------YDDAASIKTKTALVTRLGLGGTSVWAMGYEN 328 >3CZ8-A nrPDB Length = 319 Score = 147 bits (370), Expect = 1e-35, Method: Composition-based stats. Identities = 55/290 (18%), Positives = 106/290 (36%), Gaps = 49/290 (16%) Query: 79 EFNGLKKMNPKLKTLLAIGGWNFGTQKFTDMVATANNRQTFVNSAIRFLRKYSFDGLDLD 138 E +++ P L T+ + F T+ ++ R VN+ + + G+ +D Sbjct: 60 ETTWQRRVTP-LATITNLTSGGFSTEIVHQVLNNPTARTNLVNNIYDLVSTRGYGGVTID 118 Query: 139 WEYPGSQGSPAVDKERFTTLVQDLANAFQQEAQTSGKERLLLSAAVPAGQTYV---DAGY 195 +E A D++ FT ++ L + Q +L+ AVPA + GY Sbjct: 119 FE-----QVSAADRDLFTGFLRQLRDRLQAGG-------YVLTIAVPAKTSDNIPWLRGY 166 Query: 196 EVDKIAQNLDFVNLMAYDFHGSWEKVTGHNSPLYKRQEESGAAASLNVDAAVQQWLQKGT 255 + I ++++ +MAYD+H + E G A + ++ Sbjct: 167 DYGGIGAVVNYMFIMAYDWHHA--------------GSEPGPVAPITEIRRTIEFTIAQV 212 Query: 256 PASKLILGMPTYGRSFTLASSSDTRVGAPATGSGTPGPFTKEGGMLAYYEVCSWKGATKQ 315 P+ K+I+G+P YG + + P + + + E A Q Sbjct: 213 PSRKIIIGVPLYGYDWII----------PYQPGTVASAISNQNAI----ERAMRYQAPIQ 258 Query: 316 RIQDQKVP-YIFRD----NQWVGFDDVESFKTKVSYLKQKGLGGAMVWAL 360 + + P + + D V F+ V S K+ +++ L W L Sbjct: 259 YSAEYQSPFFRYSDQQGRTHEVWFEGVRSMSRKMQIVREYRLQAIGAWQL 308 >3CO4-A nrPDB Length = 312 Score = 118 bits (296), Expect = 5e-27, Method: Composition-based stats. Identities = 56/321 (17%), Positives = 118/321 (36%), Gaps = 63/321 (19%) Query: 46 LDPSLCTHLIYAFAGMTNHQLSTTEWNDETLYQEFNGLKK--MNPKLKTLLAIGGWNFGT 103 ++ TH+ +FA + + N + + +++ +K L+++ Sbjct: 24 IEWKYLTHINASFARV----KADGTLNINPVRKRIESVRETAHKHNVKILISLA--KNSP 77 Query: 104 QKFTDMVATANNRQTFVNSAIRFLRKYSFDGLDLDWEYPGSQGSPAVDKERFTTLVQDLA 163 +FT + R+ + I F ++Y DG D+D+E DK F +L+ Sbjct: 78 GEFTTAINDPKARKELIQQIIAFTKEYKLDGFDIDYE-----EYDNWDK-NFPSLL---- 127 Query: 164 NAFQQEAQTSGKERLLLSAAVPAGQTYVDAGYEVDKIAQNLDFVNLMAYDFHGSWEKVTG 223 F + + ++ +L++ AV +++ G E Q D++NLM+YD G++ Sbjct: 128 -VFARGLYLAKEKNMLMTCAV--NSRWLNYGTE---WEQYFDYINLMSYD-RGAFTDKPV 180 Query: 224 HNSPLYKRQEESGAAASLNVDAAVQQWLQK-GTPASKLILGMPTYGRSFTLASSSDTRVG 282 ++ ++ ++ W ++ SK++ G+P YG S+ Sbjct: 181 QHASYDDFVKD------------LKYWNEQCRASKSKIVGGLPFYGYSWE---------- 218 Query: 283 APATGSGTPGPFTKEGGMLAYYEVCSWKGATKQRIQDQKVPYIFRDNQWVGFDDVESFKT 342 G G+ Y + G + Y ++ + Sbjct: 219 -----ESLQGAVDDVRGI-RYSGILKHLGNEAADKDNIGKTY---------YNGRPTIAN 263 Query: 343 KVSYLKQKGLGGAMVWALDLD 363 K ++K+ G M+W L D Sbjct: 264 KCKFIKENDYAGVMIWQLFQD 284 >4S3J-A nrPDB Length = 433 Score = 104 bits (260), Expect = 8e-23, Method: Composition-based stats. Identities = 56/325 (17%), Positives = 112/325 (34%), Gaps = 45/325 (13%) Query: 44 KDLDPSLCTHLIY-AFAGMTNHQLSTTEWNDETLYQEFNGLKKMNPKLKTLLAIGGWNFG 102 + ++P L T+L Y +F + L + + P L + I NF Sbjct: 127 RAINPFL-TYLAYFSFEAKRDGTLKEPTETAK--IANIATQGQTIPML-VITNIENGNFS 182 Query: 103 TQKFTDMVATANNRQTFVNSAIRFLRKYSFDGLDLDWEYPGSQGSPAVDKERFTTLVQDL 162 + ++ A + F+ + ++ KY + D+E D+E + ++++ Sbjct: 183 ADLTSVILRDATIQNKFITNILQTAEKYGMRDIHFDFE-----SVAPEDREAYNRFLRNV 237 Query: 163 ANAFQQEAQTSGKERLLLSAAVPAGQTYVDAGYEVDKIAQNLDFVNLMAYDFHGSWEKVT 222 S L+ + ++ Q +DFV +M YD+ W+ Sbjct: 238 KIRLPSGYTLSTT---LVPKTSSNQKGKFFEAHDYKAQGQIVDFVVIMTYDW--GWQG-- 290 Query: 223 GHNSPLYKRQEESGAAASLNVDAAVQQWLQKGTPASKLILGMPTYGRSFTLASSSDTRVG 282 A + + V Q+ + P K+++G YG + L Sbjct: 291 ----------GPPMAISPIGPVKEVLQYAKSQMPPQKIMMGQNLYGFDWKL--------- 331 Query: 283 APATGSGTPGPFTKEGGMLAYYEVCSWKGATKQRIQDQKVPYI--FRDN---QWVGFDDV 337 P P +A + + + P+ F +N V F+D Sbjct: 332 -PFKQGNPPAKAVSSVAAVA---LARKYNVPIRYDFTAQAPHFNYFDENGVQHEVWFEDA 387 Query: 338 ESFKTKVSYLKQKGLGGAMVWALDL 362 S ++K + +K++G+GG W + L Sbjct: 388 RSIQSKFNLMKEQGIGGISYWKIGL 412 >4S3K-A nrPDB Length = 436 Score = 100 bits (248), Expect = 2e-21, Method: Composition-based stats. Identities = 55/304 (18%), Positives = 107/304 (35%), Gaps = 49/304 (16%) Query: 90 LKTLLAIGGWNFGTQKFTDMVATANNRQTFVNSAIRFLRKYSFDGLDLDWEYPGSQGSPA 149 L L I F + ++ + + T +N+ ++ ++ +F + D+E+ Sbjct: 171 LMVLANIENGAFSDEVGRAILNNKDVQDTLLNNIVKTAKEQNFRDIHFDFEF-----LRP 225 Query: 150 VDKERFTTLVQDLANAFQQEAQTSGKERLLLSAAVPAGQTYVDAG-----YEVDKIAQNL 204 DKE + +Q Q E +LL+S A+ + G ++ I + Sbjct: 226 ADKEAYIAFLQKAKKRLQDE-------QLLMSVALAPKTSRDQKGKWYEAHDYKAIGEIA 278 Query: 205 DFVNLMAYDFHGSWEKVTGHNSPLYKRQEESGAAASLNVDAAVQQWLQKGTPASKLILGM 264 +FV M Y++ A + + V ++ P+SK+I+G Sbjct: 279 NFVVPMTYEWG--------------YSGGPPMAVSPIGPVRDVLEYAVSEIPSSKIIMGQ 324 Query: 265 PTYGRSFTLASSSDTRVGAPATGSGTPGPFTKEGGMLAYYEVCSWKGATKQRIQDQKVPY 324 YG +TL P G + E+ + Q + P+ Sbjct: 325 NLYGYDWTL----------PYKPGGEYAKAISPQRAI---ELAARYKVAIQYDNKAQAPF 371 Query: 325 -IFRD----NQWVGFDDVESFKTKVSYLKQKGLGGAMVWALDLDDFAGFSCNQGRYPLIQ 379 ++D V F+D S + K +K+ L G W L LD + + + + + Sbjct: 372 FRYKDEQQRTHEVWFEDARSIQAKFDLIKELKLRGMAYWKLGLDFPQNWLLIEDNFKITK 431 Query: 380 TLRQ 383 + Q Sbjct: 432 RVTQ 435 >5JH8-A nrPDB Length = 317 Score = 97.4 bits (241), Expect = 1e-20, Method: Composition-based stats. Identities = 59/346 (17%), Positives = 118/346 (34%), Gaps = 59/346 (17%) Query: 26 CYFTNWAQYRQGEARFLPKDLDPSLCTHLIYAFAGMTNHQLSTTEWNDETLYQEFNGLKK 85 Y N+A + A F +D F +T T + L + Sbjct: 10 GYAGNYAALTRYAASFNAVAVD----------FYNITAQGAVTGNGDPAPNDAISFLLGR 59 Query: 86 MNPKLKTLLAI-GGWNFGTQKFTDMVATANNRQTFVNSAIRFLRKYSFDGLDLDWEYPGS 144 P + + G N+ + +A ++ V + ++F + F G+++D+E Sbjct: 60 KIPAYGCVSNVDGNGNWSADIAHAVSTSAQSQA--VANLVKFAQDKRFSGINVDFE---- 113 Query: 145 QGSPAVDKERFTTLVQDLANAFQQEAQTSGKERLLLSAAVPAGQTY---VDAGYEVDKIA 201 D+ F+ +Q L A + +L++S + + + GY++ + Sbjct: 114 -AVAQGDRNNFSHFIQVLGRALHAKGL-----KLIVSVPAFSAKDENHPANYGYDLRALG 167 Query: 202 QNLDFVNLMAYDFHGSWEKVTGHNSPLYKRQEESGAAASLNVDAAVQQWLQKGTPASKLI 261 D++ +M+YD + G A + + + PA+K++ Sbjct: 168 AAADYLQIMSYDEA--------------IPAWDPGPVAGSDWMEDDLDYAVERVPAAKIL 213 Query: 262 LGMPTYGRSFTLASSSDTRVGAPATGSGTPGPFTKEG--GMLAYYEVCSWKGATKQRIQ- 318 G+P YG + G G + ++A Y A + Sbjct: 214 NGIPAYGYDWKR--------------PGDGGMLYWKDTQALIARYGAQPRYDAGTHSLTF 259 Query: 319 DQKVPYIFRDNQWVGFDDVESFKTKVSYLKQKGLGGAMVWALDLDD 364 + R W ++ S K S + GLGG ++AL ++D Sbjct: 260 NYGAADGSRHTVWT--ENARSVALKASLVNAYGLGGTSLYALGMED 303 >3BXW-B nrPDB Length = 393 Score = 68.5 bits (166), Expect = 6e-12, Method: Composition-based stats. Identities = 53/353 (15%), Positives = 123/353 (34%), Gaps = 63/353 (17%) Query: 24 LVCYFTNWAQYRQGEARFLPKDLDPSLCTHLIYAFAGMTNHQLSTTEWNDETLYQE--FN 81 ++ Y T W + + + S T + + + E + Sbjct: 81 VLGYVTPWNSHG-----YDVTKVFGSKFTQISPVWLQLKRRGREMFEVTGLHDVDQGWMR 135 Query: 82 GLKKMNPKLKTLLAI--GGWNFGTQKFTDMVATANNRQTFVNSAIRFLRKYSFDGLDLD- 138 ++K L + + W + F +++ + + + + ++ + FDG ++ Sbjct: 136 AVRKHAKGLHIVPRLLFEDWTYDD--FRNVLDSEDEIEELSKTVVQVAKNQHFDGFVVEV 193 Query: 139 WEYPGSQGSPAVDKERFTTLVQDLANAFQQEAQTSGKERLLLSAAVPAGQTYVDAGY--E 196 W + + ++ LA A Q + L++ A+ G + E Sbjct: 194 W-----NQLLSQKRVGLIHMLTHLAEALHQARLLA---LLVIPPAITPGTDQLGMFTHKE 245 Query: 197 VDKIAQNLDFVNLMAYDFHGSWEKVTGHNSPLYKRQEESGAAASLNVDAAVQQWLQKGTP 256 +++A LD +LM YD+ + G N+PL S A + V +W Sbjct: 246 FEQLAPVLDGFSLMTYDYSTA--HQPGPNAPL------SWVRACVQVLDPKSKW------ 291 Query: 257 ASKLILGMPTYGRSFTLASSSDTRVGAPATGSGTPGPFTKEGGMLAYYEVCSWKGATKQR 316 SK++LG+ YG + + + P G+ + + K + Sbjct: 292 RSKILLGLNFYGMDYATSKDARE----PVVGA---------------RYIQTLKDHRPRM 332 Query: 317 IQDQKVP---YIFRDN----QWVGFDDVESFKTKVSYLKQKGLGGAMVWALDL 362 + D + + ++ + V + ++S + ++ ++ G+ G +W L Sbjct: 333 VWDSQASEHFFEYKKSRSGRHVVFYPTLKSLQVRLELARELGV-GVSIWELGQ 384 >3SIM-A nrPDB Length = 275 Score = 55.8 bits (133), Expect = 3e-08, Method: Composition-based stats. Identities = 29/167 (17%), Positives = 66/167 (39%), Gaps = 10/167 (5%) Query: 78 QEFNGLKKMNPKLKTLLAIGGWNFGTQKFT-DMVATANNRQTFVNSAIRFLRKYSFDGLD 136 + + +K +P ++ +++GG + G+ + + V S R +++Y+ DG+D Sbjct: 64 DQISAIKSSHPNVRVAVSLGGASVGSNTVQFQAASVDSWVSNAVTSLTRIIQRYNLDGID 123 Query: 137 LDWEYPGSQGSPAVDKERFTTLVQDLANAFQQEAQTSGKERLLLSAAVPAGQTYVDAGYE 196 +D+E+ DK F + L ++ S +S + Y+ E Sbjct: 124 IDYEH-----FQNTDKNTFAECIGRLITTLKKNGVISFAS---ISPFPSVDEYYLALFNE 175 Query: 197 VDKIAQNLDFVNLMAYDFHGSWEKVTGHNSPLYKRQEESGAAASLNV 243 ++++ AYD S +K G+ + + + S + Sbjct: 176 YKNAINHINY-QFKAYDSSTSVDKFLGYYNNAASKYKGGNVLISFST 221 >3EBV-A nrPDB Length = 302 Score = 55.8 bits (133), Expect = 4e-08, Method: Composition-based stats. Identities = 45/249 (18%), Positives = 75/249 (30%), Gaps = 49/249 (19%) Query: 91 KTLLAIGGWNFGTQKFTDMVATANNRQTFVNSAIRFLRKYSFDGLDLDWEYPGSQGSPAV 150 K ++++GG +K T V ++ + F NS +R+Y FDG+D+D E Sbjct: 77 KVIISVGG-----EKGTVSVNSSASATNFANSVYSVMREYGFDGVDIDLE---------- 121 Query: 151 DKERFTTLVQDLANAFQQEAQTSGKERLLLSAAVPAGQTYVDAGYEVDKIAQNLDFVNL- 209 + T + Q L A +A ++L+ A G D + + Sbjct: 122 NGLNPTYMTQALR-ALSAKA----GPDMILTMAPQTIDMQSTQGGYFQTALNVKDILTVV 176 Query: 210 -MAYDFHGSWEKVTGHNSPLYKRQEESGAAASLNVDAAVQQW-------LQKGTPASKLI 261 M Y Y G + V L+ G S++ Sbjct: 177 NMQY----------------YNSGTMLGCDGKVYAQGTVDFLTALACIQLEGGLAPSQVG 220 Query: 262 LGMPTYGRSFTLASSSDTRVGAPATGSGTPGPFTKEGGMLAYYEVCSWKGA-TKQRIQDQ 320 LG+P R+ A T G +GA T D Sbjct: 221 LGLPASTRA---AGGGYVSPSVVNAALDCLTKATNCGSFKPSKTYPDLRGAMTWSTNWDA 277 Query: 321 KVPYIFRDN 329 + ++ Sbjct: 278 TAGNAWSNS 286 >3IAN-A nrPDB Length = 321 Score = 54.7 bits (130), Expect = 8e-08, Method: Composition-based stats. Identities = 48/260 (18%), Positives = 89/260 (34%), Gaps = 38/260 (14%) Query: 24 LVCYFTNWAQ-----YRQGEARFLPKDLDPSLCTHLIYAFAGMTNHQ----LSTTEWNDE 74 LV Y+ NW Y+ G + + +F Q D Sbjct: 7 LVGYWHNWKSTGKDGYKGGSSADFNLSSTQEGYNVINVSFMKTPEGQTLPTFKPYNKTDT 66 Query: 75 TLYQEFNGLKKMNPKLKTLLAIGGWNFGTQKFTDMVATANNRQTFVNSAIRFLRKYSFDG 134 E + L L+A+GG ++ + + FVN IR + Y FDG Sbjct: 67 EFRAEISKLNAEGKS--VLIALGG----ADAHIELKKSQES--DFVNEIIRLVDTYGFDG 118 Query: 135 LDLDWEYPGSQGSPAVDKERFT-TLVQDLANAFQQEAQTSGKERLLLSAAVPAGQTYVDA 193 LD+D E A D + + ++ + + ++++ + +++ A Sbjct: 119 LDIDLE---QAAIEAADNQTVIPSALKKVKDHYRKDGKN-----FMITMAPEFPYLTSSG 170 Query: 194 GY--EVDKIAQNLDFVNLMAYDFHGSWEKVTGHNSPLYKRQEESGAAASLNVDAAVQQWL 251 Y ++ + DF+N Y+ G + + ++ Q + Q L Sbjct: 171 KYAPYINNLDSYYDFINPQYYNQGG--DGFWDSDLNMWISQSNDEKKEDF--LYGLTQRL 226 Query: 252 QKG------TPASKLILGMP 265 G PASK ++G+P Sbjct: 227 VTGTDGFIKIPASKFVIGLP 246 >4Z4A-A nrPDB Length = 121 Score = 54.7 bits (130), Expect = 9e-08, Method: Composition-based stats. Identities = 21/84 (25%), Positives = 37/84 (44%), Gaps = 18/84 (21%) Query: 389 YLPSGTPELEVPKPGQPSEPEHGPSPGQDTFCQGKADGLYPNPRERSSFYSCA------- 441 Y+ TP P + + T C G D LYP+P+ + + C+ Sbjct: 18 YVQDKTPAFVCPA-----------ADIKTTKCLGPKDCLYPSPKTCNGYIQCSPADDSYL 66 Query: 442 AGRLFQQSCPTGLVFSNSCKCCTW 465 G + + CP+GL+++++ K C W Sbjct: 67 TGIIHEMPCPSGLLWNDNKKWCDW 90 >4TX8-A nrPDB Length = 439 Score = 53.9 bits (128), Expect = 1e-07, Method: Composition-based stats. Identities = 65/355 (18%), Positives = 105/355 (29%), Gaps = 64/355 (18%) Query: 24 LVCYFTNWAQYRQGEARFLPKDLDPSLCTHLIYAFAGMTNH-----QLSTTEWNDETLYQ 78 LV Y W + P + ++ AFA + L + Q Sbjct: 109 LVGY---WHNFANPSGSAFPLSQVSADWDVIVVAFADDAGNGNVSFTLDPAAGSAAQFIQ 165 Query: 79 EFNGLKKMNPKLKTLLAIGGWNFGTQKFTDMVATANNRQTFVNSAIRFLRKYSFDGLDLD 138 + + K +L++GG N + A Q FVNS L +Y FDG+DLD Sbjct: 166 DIRAQQAKGK--KVVLSLGGQNGSVT-----LNNATQVQNFVNSLYGILTQYGFDGIDLD 218 Query: 139 WEYPGSQGSPAVDKERFTTLVQDLANAFQQEAQTSGKER--LLLSAAVPAGQTYVDAGYE 196 E A + V+ L S + V G + Sbjct: 219 LESGSGIVVGAPVVSNLVSAVKQLKAKIGPNFYLSMAPEHPYVQGGFVAYGGNWGAYLPI 278 Query: 197 VDKIAQNLDFVNLMAYDFHGSWEKVTGHNSPLYKRQEESGAAASLNVDAAV--QQWLQKG 254 +D + +L +++ Y+ N LY +G A + D V + L +G Sbjct: 279 IDGLRDDLSVIHVQYYN-----------NGGLY-TPYSTGVLAEGSADMLVGGSKMLIEG 326 Query: 255 TPASKLILGMPTYGRSFTLASSSDTRVGAPATGSGTPGPFTKEGGMLAYYEVCSWKGATK 314 P + G SF G P+ S F +A C Sbjct: 327 FPIANGASG------SFKGLRPDQVAFGVPSGRSSANSGFVTAD-TVAKALTCLTTLQGC 379 Query: 315 QRIQDQKVPYIFRDNQWVGFDDVESFKTKVSYLKQKGLGGAMVWALDLDDFAGFS 369 ++ + FR G M W+++ D G++ Sbjct: 380 GSVKPAQAYPAFR--------------------------GVMTWSINWDRRDGYT 408 >4RL3-A nrPDB Length = 272 Score = 53.1 bits (126), Expect = 3e-07, Method: Composition-based stats. Identities = 40/234 (17%), Positives = 79/234 (33%), Gaps = 30/234 (12%) Query: 40 RFLPKDLDPSLCTHLIYAFA-------GMTNHQLSTTEWNDETLYQEFNGLKKMNPKLKT 92 +F ++ + H I AFA TN + N +K + +K Sbjct: 16 QFTDVPINSGVTFHFILAFAIDYTSAAAATNGVFNIYWQNSVLTPAAVQAIKAQHSNVKV 75 Query: 93 LLAIGGWNFGTQKFTDMVATANN-RQTFVNSAIRFLRKYSFDGLDLDWEYPGSQGSPAVD 151 ++++GG + ++ V+S + +Y DG+D+D+E+ V Sbjct: 76 MVSLGGDTISGSPVQFTATSVSSWVANAVSSLTSLINQYHLDGIDIDYEH-----FDQVS 130 Query: 152 KERFTTLVQDLANAFQQEAQTSGKERLLLSAAVPAGQTYVDAGYE--VDKIAQNLDFVNL 209 F + + L + ++S A A V++ Y + + +D VN Sbjct: 131 TSTFVSCIGQLITQLKANN--------VISVASIAPFDGVESQYTALFGQYSSVIDLVNF 182 Query: 210 MAYDFHGSWEKVTGHNSPLYKRQEESGAAASLNVDAAVQQWLQKGT-PASKLIL 262 Y G ++ Y + A+ + + G PA +L Sbjct: 183 QFY------SYGAGTSASQYVSLYNTAASKYGGGAKVLASFSTGGVGPAPSTVL 230 >3N18-A nrPDB Length = 333 Score = 52.3 bits (124), Expect = 4e-07, Method: Composition-based stats. Identities = 51/261 (19%), Positives = 81/261 (31%), Gaps = 45/261 (17%) Query: 24 LVCYFTNWAQYRQGEARFLPKDLDPSLCTHLIYAFAGMTNH----QLSTTEWNDETLYQE 79 LV Y W + G KD+ P + +F + S D + Sbjct: 9 LVGY---WHNFDNGTGIIKLKDVSP-KWDVINVSFGETGGDRSTVEFSPVYGTDADFKSD 64 Query: 80 FNGLKKMNPKLKTLLAIGGWNFGTQKFTDMVATANNRQTFVNSAIRFLRKYSFDGLDLDW 139 + LK K +L+IGG Q ++ + F+NS + KY FDG+D+D Sbjct: 65 ISYLKSKGK--KVVLSIGG-----QNGVVLLPDNAAKDRFINSIQSLIDKYGFDGIDIDL 117 Query: 140 EYPGSQGSPAVDKERF--------TTLVQDLANAFQQEAQTSGKERLLLSAAVPAGQTYV 191 GS + F L+ + LLS A YV Sbjct: 118 ---GSGIYLNGNDTNFKNPTTPQIVNLISAIRTISDHYG-----PDFLLSMA--PETAYV 167 Query: 192 DAGY--EVDKIAQNLDFVNLMAYDFHGSWEKVTGHNSPLYKRQEESGAAASLNVDAAVQQ 249 GY L + +G +K+T + + G + N + Sbjct: 168 QGGYSAYGSIWGAYLPII-------YGVKDKLTYIHVQHFNAGSGIGMDGN-NYNQGTAD 219 Query: 250 WLQKGTPASKLILGMPTYGRS 270 + L+ G P G + Sbjct: 220 YEVAMADM--LLHGFPVGGNA 238 >1NAR-A nrPDB Length = 290 Score = 48.1 bits (113), Expect = 8e-06, Method: Composition-based stats. Identities = 31/148 (20%), Positives = 61/148 (41%), Gaps = 32/148 (21%) Query: 78 QEFNGLKKMNPKLKTLLAIGGWNFGTQKFTDMVATANNRQTFVNSAIR----FLRKYS-- 131 ++ LK+ +P++K +++IGG T +V++A ++KYS Sbjct: 66 EKVKNLKRRHPEVKVVISIGGRGVNTPF------DPAEENVWVSNAKESLKLIIQKYSDD 119 Query: 132 ----FDGLDLDWEYPGSQGSPAVDKERFTTLVQDLANAFQQEAQTSGKERLLLSAAVP-A 186 DG+D+ +E+ S E F TL+ L +++ + ++S A Sbjct: 120 SGNLIDGIDIHYEHIRSD-------EPFATLMGQLITELKKDDDLNIN---VVSIAPSEN 169 Query: 187 GQTYVDAGYEVDKIAQNLDFVNLMAYDF 214 ++ Y K D++N + Y F Sbjct: 170 NSSHYQKLYNAKK-----DYINWVDYQF 192 >4AXN-A nrPDB Length = 328 Score = 46.6 bits (109), Expect = 2e-05, Method: Composition-based stats. Identities = 58/369 (15%), Positives = 117/369 (31%), Gaps = 98/369 (26%) Query: 15 MIPWGSAAK-LVCYFTNWA---QYRQGEARFLPKDLDPSLCTHLIYAFAGMTNHQLSTTE 70 ++P + K L+ ++ NWA + +F +L + + A A M + T + Sbjct: 17 IMPSIANKKILMGFWHNWAAGASDGYQQGQFANMNLTDIPTEYNVVAVAFMKGQGIPTFK 76 Query: 71 ---WNDETLYQEFNGLKKMNPKLKTLLAIGGWNFGTQKFTDMVATANNRQTFVNSAIRFL 127 +D ++ L L+++GG ++ + IR + Sbjct: 77 PYNLSDTEFRRQVGVLNSQGR--AVLISLGG----ADAHIELKTGDE--DKLKDEIIRLV 128 Query: 128 RKYSFDGLDLDWEYPGSQGSPAVDKERFTTLVQDLANAFQQEAQTSGKERLLLSAAVPAG 187 Y FDGLD+D E + A +K ++ + + + + + ++S A Sbjct: 129 EVYGFDGLDIDLE--QAAIGAANNKTVLPAALKKVKDHYAAQGKN-----FIISMAPEFP 181 Query: 188 QTYVDAGYEVDKIAQNLDFVNLMA--YDFHGSWEKVTGHNSPLYKRQEESGAAASLNVDA 245 + Y LD++N + YDF +P Y Q G Sbjct: 182 YLRTNGTY--------LDYINALEGYYDFI----------APQYYNQGGDGI-----WVD 218 Query: 246 AVQQWLQKGTPASK----------LILGMPTYGRSFTLASSSDTRVGAPATGSGTPGPFT 295 + W+ + A K L+ G R + ++ +G P+ + Sbjct: 219 ELNAWITQNNDAMKEDFLYYLTESLVTG----TRGYAKIPAAKFVIGLPSNNDAAATGYV 274 Query: 296 KEGGMLAYYEVCSWKGATKQRIQDQKVPYIFRDNQWVGFDDVESFKTKVSYLKQKGLGGA 355 +++ Y N + D K + G Sbjct: 275 V----------------------NKQAVY----NAFSRLD-----------AKNLSIKGL 297 Query: 356 MVWALDLDD 364 M W+++ D+ Sbjct: 298 MTWSINWDN 306 >6BN0-A nrPDB Length = 79 Score = 46.2 bits (108), Expect = 3e-05, Method: Composition-based stats. Identities = 20/72 (27%), Positives = 32/72 (44%), Gaps = 12/72 (16%) Query: 402 PGQPSEPEHGPSPGQDTFCQGKADGLYPNPRERSSFYSC------AAGRLFQQSCPTGLV 455 P P +P+ DT C G D LYPNP +++ C + + CP GL Sbjct: 2 PYNPCKPQEVI----DTKCMGPKDCLYPNPDSCTTYIQCVPLDEVGNAKPVVKPCPKGLQ 57 Query: 456 FSNS--CKCCTW 465 ++++ K C + Sbjct: 58 WNDNVGKKWCDY 69 >4W5Z-A nrPDB Length = 345 Score = 45.4 bits (106), Expect = 5e-05, Method: Composition-based stats. Identities = 44/259 (16%), Positives = 83/259 (32%), Gaps = 34/259 (13%) Query: 24 LVCYFTNWAQYRQGEARFLP----KDLDPSLCTHLIYAFA---GMTNHQLSTTEWN---- 72 +V Y+ NW R + P K ++P + +F + ++ T + + Sbjct: 33 VVGYWHNWCDGRGYQGGNAPCVELKTVNP-QYNVVNISFMKVYDIAEGRIPTFKLDPTIA 91 Query: 73 --DETLYQEFNGLKKMNPKLKTLLAIGGWNFGTQKFTDMVATANNRQTFVNSAIRFLRKY 130 + + + L L+A+GG ++ IR Y Sbjct: 92 LSEAEFIAQIDTLNSQGRS--VLIALGG----ADAHIELTRGDE--DALAAEIIRLTDLY 143 Query: 131 SFDGLDLDWEYPGSQGSPAVDKERFTTLVQDLANAFQQEAQTSGKERLLLSAAVPAGQTY 190 FDGLD+D E + K+ + L ++ + +G ++ A T Sbjct: 144 GFDGLDIDLE-----QAAITAKDNQFVIPAAL-KMVKEHYRKTGDNFMITMAPEFPYLTA 197 Query: 191 VDAGYEV-DKIAQNLDFVNLMAYDF--HGSWEKVTGHNSPLYKRQEESGAAASLNVDAAV 247 A ++ DF+N Y+ G W + G + D+ + Sbjct: 198 NGAYTPYLTELDGYYDFINPQFYNQGGDGLWIEGVGWIAQ--NNDALKEEFIYYIADSLI 255 Query: 248 QQWLQ-KGTPASKLILGMP 265 P KL+ G+P Sbjct: 256 NGTRNYHKIPHDKLVFGLP 274 >2Y8V-A nrPDB Length = 290 Score = 45.4 bits (106), Expect = 5e-05, Method: Composition-based stats. Identities = 35/172 (20%), Positives = 62/172 (36%), Gaps = 15/172 (8%) Query: 22 AKLVCYFTNWAQYRQGEARFLPKDLDPSLCTHLIYAFAGMTNHQLSTTEWNDETLYQEFN 81 +++CY R LP + + TH+I A + T +D ++ +N Sbjct: 13 RRVICYHQTLCPNRGDYVSVLPLVKNNTGVTHIIIAAFHLNEDPGHITLNDDPPDHEMYN 72 Query: 82 GLKKMNP-----KLKTLLAIGGWNFGTQKFTDMVATANNRQTFVNSAIRFLRKYSFDGLD 136 L P +K + +GG G+ + + + + + +R++ DGLD Sbjct: 73 PLWAEVPVLKRSGVKVMGMLGGAAQGS--YRCLDGDQEKFERYYQPLLAMVRRHQLDGLD 130 Query: 137 LDWE----YPGSQGSPAVDK----ERFTTLVQDLANAFQQEAQTSGKERLLL 180 LD E PG K + F + +A A SG + L Sbjct: 131 LDVEEEMSLPGIIRLIDRLKLDLGDDFIITLAPVAAALLGIGNLSGFDYRQL 182 >1EDT-A nrPDB Length = 271 Score = 45.4 bits (106), Expect = 5e-05, Method: Composition-based stats. Identities = 26/141 (18%), Positives = 47/141 (33%), Gaps = 16/141 (11%) Query: 32 AQYRQGEARFLPKDLDPSLCTHLIY------AFAGMTNHQLSTTEWNDETLYQEFNGLKK 85 +Y + D+ ++ Y A+ + + + L++ Sbjct: 26 GKYTLADGGGNAFDVAVIFAANINYDTGTKTAYLHFNENVQRVLD----NAVTQIRPLQQ 81 Query: 86 MNPKLKTLLAIGGWNFGTQKFTDMVATANNRQTFVNSAIRFLRKYSFDGLDLDWEYP--G 143 +K LL++ G N F + + F + KY DG+D D EY G Sbjct: 82 QG--IKVLLSVLG-NHQGAGFANFPSQQAA-SAFAKQLSDAVAKYGLDGVDFDDEYAEYG 137 Query: 144 SQGSPAVDKERFTTLVQDLAN 164 + G+ + F LV L Sbjct: 138 NNGTAQPNDSSFVHLVTALRA 158 >4MB4-A nrPDB Length = 528 Score = 43.5 bits (101), Expect = 2e-04, Method: Composition-based stats. Identities = 44/259 (16%), Positives = 83/259 (32%), Gaps = 34/259 (13%) Query: 24 LVCYFTNWAQYRQGEARFLP----KDLDPSLCTHLIYAFA---GMTNHQLSTTEWN---- 72 +V Y+ NW R + P K ++P + +F + ++ T + + Sbjct: 11 VVGYWHNWCDGRGYQGGNAPCVELKTVNP-QYNVVNISFMKVYDIAEGRIPTFKLDPTIA 69 Query: 73 --DETLYQEFNGLKKMNPKLKTLLAIGGWNFGTQKFTDMVATANNRQTFVNSAIRFLRKY 130 + + + L L+A+GG ++ IR Y Sbjct: 70 LSEAEFIAQIDTLNSQGRS--VLIALGG----ADAHIELTRGDE--DALAAEIIRLTDLY 121 Query: 131 SFDGLDLDWEYPGSQGSPAVDKERFTTLVQDLANAFQQEAQTSGKERLLLSAAVPAGQTY 190 FDGLD+D Q + K+ + L ++ + +G ++ A T Sbjct: 122 GFDGLDID-----LQQAAITAKDNQFVIPAAL-KMVKEHYRKTGDNFMITMAPEFPYLTA 175 Query: 191 VDAGYEV-DKIAQNLDFVNLMAYDF--HGSWEKVTGHNSPLYKRQEESGAAASLNVDAAV 247 A ++ DF+N Y+ G W + G + D+ + Sbjct: 176 NGAYTPYLTELDGYYDFINPQFYNQGGDGLWIEGVGWIAQ--NNDALKEEFIYYIADSLI 233 Query: 248 QQWLQ-KGTPASKLILGMP 265 P KL+ G+P Sbjct: 234 NGTRNYHKIPHDKLVFGLP 252 >4NUY-A nrPDB Length = 899 Score = 42.3 bits (98), Expect = 4e-04, Method: Composition-based stats. Identities = 57/332 (17%), Positives = 107/332 (32%), Gaps = 63/332 (18%) Query: 26 CYFTNWAQYRQGEA--------RFLPKDLDPSLCTHLIYAFAGMTNHQLSTTEWNDETLY 77 YF W LPK++D L + F T + Sbjct: 19 GYFRTWHDKTSDPTEKDKVNSMGELPKEVD------LAFIFHDWTKDYSLFWKELATKHV 72 Query: 78 QEFNGLKKMNPKLKTLL---AIGGWNFG-TQKFTDMVATANNRQTFVNSAIR-FLRKYSF 132 + N K+ ++T+ GG N G + + T + + + ++ KY+ Sbjct: 73 PKLN--KQGTRVIRTIPWRFLAGGDNSGIAEDTSKYPNTPEGNKALAKAIVDEYVYKYNL 130 Query: 133 DGLDLDWEYPGSQGSPAVDKERFTTLVQDLANAFQQEAQTSG-----KERLLLSAAVPAG 187 DGLD+D E+ P VDK+ T V+ F++ + G K RL + + Sbjct: 131 DGLDVDVEH---DSIPKVDKKEDTAGVERSIQVFEEIGKLIGPKGVDKSRLFIMDSTYMA 187 Query: 188 QTYVDAGYEVDKIAQNLDFVNLMAYDFHGSWEKVTGHNSPLYKRQEESGAAASLNVDAAV 247 I + ++NL+ +GS + G P+ R E++ Sbjct: 188 DKN-------PLIERGAPYINLLLVQVYGS-QGEKGGWEPVSNRPEKTMEERW----QGY 235 Query: 248 QQWLQKGTPASKLILGMPTY------GRSF------------TLASSSDTRVGAPATGSG 289 ++++ + ++G Y G + ++ T A Sbjct: 236 SKYIR----PEQYMIGFSFYEENAQEGNLWYDINSRKDEDKANGINTDITGTRAERYARW 291 Query: 290 TPGPFTKEGGMLAYYEVCSWKGATKQRIQDQK 321 P +GG+ +Y ++ QK Sbjct: 292 QPKTGGVKGGIFSYAIDRDGVAHQPKKYAKQK 323 >6MDV-A nrPDB Length = 802 Score = 40.8 bits (94), Expect = 0.001, Method: Composition-based stats. Identities = 54/322 (16%), Positives = 108/322 (33%), Gaps = 60/322 (18%) Query: 1 MVRSVAWAGFMVLLMIPWGSAAKL-VCYFTNW-----------AQYRQGEARFLPKDLDP 48 M ++ G ++ I G L YF W Q+ + +PK++D Sbjct: 1 MGKTDQQVGAKLVQEIREGKRGPLYAGYFRTWHDRASTGIDGKQQHPENTMAEVPKEVD- 59 Query: 49 SLCTHLIYAFAGMTNHQLSTTE-WNDETLYQEFNGLKKMNPKLKTLLAIGGWNFGTQKFT 107 +++ F +H S + W++ + L + L + + N T Sbjct: 60 -----ILFVF---HDHTASDSPFWSELKD-SYVHKLHQQGTALVQTIGVNELNGRTGLSK 110 Query: 108 DMVATANNRQTFVNSAIR-FLRKYSFDGLDLDWEYPGSQGSPAVDKERFTTLVQDLANAF 166 D T + + ++ F+ DGLD+D E+ + + R + +++A Sbjct: 111 DYPDTPEGNKALAAAIVKAFVTDRGVDGLDIDIEHEFTNKRTPEEDARALNVFKEIAQLI 170 Query: 167 QQEAQTSGKERLLLSAAVPAGQTYVDAGYEVDKIAQNLDFVNLMAYDFHGSWEKVTGHNS 226 + S K +LL+ + + IA++LD++ L Y Sbjct: 171 GKNG--SDKSKLLIMDTTLSVENNP----IFKGIAEDLDYL-LRQY-------------- 209 Query: 227 PLYKRQEESGAAASLNVDA-AVQQWLQKGTPASKLILGMPTY------GRSFTLASSSDT 279 Y Q ++N D Q ++ AS+ ++G + G + ++ Sbjct: 210 --YGSQGGEAEVDTINSDWNQYQNYI----DASQFMIGFSFFEESASKGNLW--FDVNEY 261 Query: 280 RVGAPATGSGTPGPFTKEGGML 301 P G G K+ Sbjct: 262 DPNNPEKGKDIEGTRAKKYAEW 283 >1F8Q-A nrPDB Length = 263 Score = 38.9 bits (89), Expect = 0.004, Method: Composition-based stats. Identities = 22/127 (17%), Positives = 42/127 (33%), Gaps = 12/127 (9%) Query: 148 PAVDKERFTTLVQDLANAFQQEAQTSGKERLLLSAAVPAGQTYVDAGYEVDK----IAQN 203 D + ++DL NA + LLL + AG+ + + D +A + Sbjct: 7 SGADPRSYGMFIKDLRNALPFREKVYNIP-LLLPSVSGAGRYLLMHLFNRDGKTITVAVD 65 Query: 204 LDFVNLMAYDFHGSWEKVTGHNSPLYK-----RQEESGAAASLNVDAAVQQWLQKGTPAS 258 + V +M Y + + R + D + + G P Sbjct: 66 VTNVYIMGY-LADTTSYFFNEPAAELASQYVFRDARRKITLPYSGDYE-RLQIAAGKPRE 123 Query: 259 KLILGMP 265 K+ +G+P Sbjct: 124 KIPIGLP 130 >4GUW-A nrPDB Length = 246 Score = 38.1 bits (87), Expect = 0.009, Method: Composition-based stats. Identities = 21/127 (16%), Positives = 42/127 (33%), Gaps = 12/127 (9%) Query: 148 PAVDKERFTTLVQDLANAFQQEAQTSGKERLLLSAAVPAGQTYVDAGYEVDK----IAQN 203 D + ++DL NA + LLL + AG+ + + D +A + Sbjct: 7 SGADPSSYGMFIKDLRNALPHTEKVYNIP-LLLPSVSGAGRYLLMHLFNYDGNTITVAVD 65 Query: 204 LDFVNLMAYDFHGSWEKVTGHNSP-----LYKRQEESGAAASLNVDAAVQQWLQKGTPAS 258 + V +M Y + + R + + + + G P Sbjct: 66 VTNVYIMGY-LALTTSYFFNEPAADLASQYVFRSARRKITLPYSGNYE-RLQIAAGKPRE 123 Query: 259 KLILGMP 265 K+ +G+P Sbjct: 124 KIPIGLP 130 >2EBN-A nrPDB Length = 289 Score = 36.9 bits (84), Expect = 0.018, Method: Composition-based stats. Identities = 25/142 (17%), Positives = 51/142 (35%), Gaps = 14/142 (9%) Query: 86 MNPKLKTLLAIGGWNFGTQKFTDMVATANNRQT-FVNSAIRFLRKYSFDGLDLDWEYPGS 144 + +K +L+I G + + + + R F Y+ DG+ D EY Sbjct: 81 QDKGIKVILSILGNHDRSG----IANLSTARAKAFAQELKNTCDLYNLDGVFFDDEYSAY 136 Query: 145 QGSPAVDKERFTTLVQDLANAFQQEAQTSGKERLLLSAAVPAGQTYVDAGYEVDKIAQNL 204 Q P F T + A E + + L++ V + + + + Sbjct: 137 QTPPPS---GFVTPSNNAAARLAYETKQA-MPNKLVTVYVYSRTSSFPTAVDGVNAGSYV 192 Query: 205 DF-VNLMAYDFHGSWEKVTGHN 225 D+ ++ D+ GS++ T + Sbjct: 193 DYAIH----DYGGSYDLATNYP 210 Score = 30.0 bits (66), Expect = 2.2, Method: Composition-based stats. Identities = 29/157 (18%), Positives = 58/157 (36%), Gaps = 19/157 (12%) Query: 229 YKRQEESGAAASLNVDAAVQQWLQKGTPASKLILGMPTYGRSFTLASSSDTRVGAPATGS 288 Y+ SG N AA + K +KL+ + Y R+ S + Sbjct: 136 YQTPPPSGFVTPSNNAAARLAYETKQAMPNKLVT-VYVYSRT------SSFPTAVDGVNA 188 Query: 289 GTPGPFTKEGGMLAYYEVCSWKGATKQRIQDQKVPYIFRDNQWVGFDDVESFKTKVSYLK 348 G+ + +Y ++ G K + F + + ++ + + Sbjct: 189 GSYVDYAIHDYGGSYDLATNYPGLAKSGM--VMSSQEFNQGR---YATAQALRN----IV 239 Query: 349 QKGLGGAMVWALDLDDFAGFSCNQGRYPLIQTLRQEL 385 KG GG M++A+D + + F+ Q P ++ + +EL Sbjct: 240 TKGYGGHMIFAMDP-NRSNFTSGQ--LPALKLIAKEL 273 >6Q64-A nrPDB Length = 364 Score = 36.2 bits (82), Expect = 0.028, Method: Composition-based stats. Identities = 29/171 (16%), Positives = 57/171 (33%), Gaps = 24/171 (14%) Query: 117 QTFVNSAIRFLRKYSFDGLDLDWEYPGSQGS---------PAVDKERFTTLVQDLANAFQ 167 + + N+ + KY+ DG D+D++ PG S + ++ L+ + Sbjct: 167 KAYANAICDSIEKYNLDGFDIDYQ-PGYGHSGTLANYQTISPSGNNKMQVFIETLSARLR 225 Query: 168 QEAQ---TSGKERLLLSAAVPAGQTYVDAGYEVDKIAQNLDFVNLMAYDFHGSWEKVTGH 224 + G+ LL + Y+ Y + + +N D WE+ T Sbjct: 226 PAGRMLVMDGQPDLLSTETSKLVDHYIYQAYWESSTSSVIYKINKPNLD---DWERKTII 282 Query: 225 NSPLYKRQEESGAAASLNVD--------AAVQQWLQKGTPASKLILGMPTY 267 + + G +V + + P+ K I G+ TY Sbjct: 283 TVEFEQGWKTGGITYYTSVRPELNSMEGNQILDYATLDLPSGKRIGGIGTY 333 >1DQC-A nrPDB Length = 74 Score = 35.8 bits (81), Expect = 0.045, Method: Composition-based stats. Identities = 14/42 (33%), Positives = 19/42 (45%) Query: 424 ADGLYPNPRERSSFYSCAAGRLFQQSCPTGLVFSNSCKCCTW 465 DG N SFY+C ++CP GL ++ K C W Sbjct: 14 DDGPNVNLYSCCSFYNCHKCLARLENCPKGLHYNAYLKVCDW 55 >2XVP-A nrPDB Length = 310 Score = 31.9 bits (71), Expect = 0.54, Method: Composition-based stats. Identities = 37/192 (19%), Positives = 57/192 (29%), Gaps = 50/192 (26%) Query: 91 KTLLAIGG-----------------WNFGTQKFTDMVATANNRQTFVNSAIRFLRKYSFD 133 K LL+IGG F F + + F + + D Sbjct: 89 KVLLSIGGAYPPDQSILSEDSAVAFATFLWGAFGPVAEGWEGPRPFGDVVV--------D 140 Query: 134 GLDLDWEYPGSQGSPAVDKERFTTLVQDLANAFQQEAQTSGKERLLLSAAVPAGQTYVDA 193 G D D E+ G G + T+V F Q + + LSAA DA Sbjct: 141 GFDFDIEHNGGFG--------YATMVNTFRQYFNQ----VPERKFYLSAA--PQCIIPDA 186 Query: 194 GYEVDKIAQNLDFVNLMAYDFHGSWEKVTGHNSPLYKRQEESGAAASLNVDAAVQQWLQK 253 DF+ + Y ++ + + N DA V Sbjct: 187 QLSDAIFNAAFDFIWIQYY-------NTAACSAKSFIDTS----LGTFNFDAWVTVLKAS 235 Query: 254 GTPASKLILGMP 265 + +KL +G+P Sbjct: 236 ASKDAKLYVGLP 247 >5KEG-A nrPDB Length = 203 Score = 31.9 bits (71), Expect = 0.59, Method: Composition-based stats. Identities = 7/28 (25%), Positives = 13/28 (46%), Gaps = 1/28 (3%) Query: 207 VNLMAYD-FHGSWEKVTGHNSPLYKRQE 233 V++M YD F W+ H ++ + Sbjct: 154 VSIMTYDEFKHCWDTFVDHQGAPFQPWD 181 >2GSJ-A nrPDB Length = 271 Score = 31.5 bits (70), Expect = 0.84, Method: Composition-based stats. Identities = 38/180 (21%), Positives = 64/180 (35%), Gaps = 39/180 (21%) Query: 88 PKLKTLLAIGGWNFGTQKFTDMVATANNR-------QTFV--NSAIRFLRKYSFDGLDLD 138 +K +L+IGG + + + R F+ S+ R L DG+D D Sbjct: 70 RGIKVMLSIGGGAGS----YSLSSVQDARSVADYIWNNFLGGRSSSRPLGDAVLDGVDFD 125 Query: 139 WEYPGSQGSPAVDKERFTTLVQDLANAFQQEAQTSGKERLLLSAAVPAGQTYVDAGYEVD 198 E+ G+ + L + L+ G +++ LSAA + D Sbjct: 126 IEHGGAY---------YDALARRLSE------HNRGGKKVFLSAAPQCP--FPDQSLNKA 168 Query: 199 KIAQNLDFVNLMAYDFHGSWEKVTGHNSPLYKRQEESGAAASLNVDAAVQQWLQKGTPAS 258 D+V + Y+ + E +G+ S R + +S N V G PAS Sbjct: 169 LSTGLFDYVWVQFYN-NPQCEFNSGNPSNF--RNSWNKWTSSFNAKFYV------GLPAS 219 >2WOQ-A nrPDB Length = 337 Score = 31.2 bits (69), Expect = 0.92, Method: Composition-based stats. Identities = 21/105 (20%), Positives = 34/105 (32%), Gaps = 13/105 (12%) Query: 206 FVNLMAYD------FHGSWEKVTGHNSPLYKRQEESGAAASLNVDAAVQQW---LQKGTP 256 V +MAY ++G + G S L K + + N D A+ + L +G Sbjct: 196 NVRIMAYSAKYASAYYGPFRDAVGSASNLGKGNKATYQMDPANSDEALHEVAADLAEGAD 255 Query: 257 ASKLILGMPTYGRSFTLASSSDTRVGAPATGSGTPGPFTKEGGML 301 + GMP + AP G + G + Sbjct: 256 MVMVKPGMPY----LDIVRRVKDEFRAPTFVYQVSGEYAMHMGAI 296 >1UZQ-A nrPDB Length = 162 Score = 30.8 bits (68), Expect = 1.2, Method: Composition-based stats. Identities = 17/79 (21%), Positives = 23/79 (29%), Gaps = 9/79 (11%) Query: 393 GTPELEVPKPGQPSEPEHGPSPGQDTFCQGKADGLYPNPRERSSFY-SCAAGR------L 445 GTP P PG + F + + E C G+ Sbjct: 86 GTPCEMCPAVNTSE--YKILCPGGEGFRPNPITVILEDIDECQELPGLCQGGKCINTFGS 143 Query: 446 FQQSCPTGLVFSNSCKCCT 464 FQ CPTG + + C Sbjct: 144 FQCRCPTGYYLNEDTRVCD 162 >2MMY-A nrPDB Length = 97 Score = 30.8 bits (68), Expect = 1.2, Method: Composition-based stats. Identities = 17/83 (20%), Positives = 27/83 (32%), Gaps = 7/83 (8%) Query: 276 SSDTRVGAPATGSG----TPGPFTKEGGMLAYYEVCSWKGATKQRIQDQKVPYIFRDNQW 331 S + + G G G F K+ G++ + +D P + Sbjct: 5 SDNNTIFVQGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKP---KGEAT 61 Query: 332 VGFDDVESFKTKVSYLKQKGLGG 354 V FDD S K + + K G Sbjct: 62 VSFDDPPSAKAAIDWFDGKEFHG 84 >4TOQ-A nrPDB Length = 273 Score = 30.4 bits (67), Expect = 1.5, Method: Composition-based stats. Identities = 35/187 (18%), Positives = 56/187 (29%), Gaps = 40/187 (21%) Query: 86 MNPKLKTLLAIGGWNFGTQKFTDMVATANNR---QTFV--NSAIRFLRKYSFDGLDLDWE 140 +K L++IGG ++ A F+ S+ R L DG+D D E Sbjct: 68 QGKDIKVLMSIGGGAGDYSLVSEADADNFADYLWNNFLGGQSSSRPLGDAVLDGIDFDIE 127 Query: 141 YPGSQGSPAVDKERFTTLVQDLANAFQQEAQTSGKERLLLSAAVPAGQTYVDAGYEVDKI 200 TT LA A + + K L + P +++DA Sbjct: 128 L------------GTTTFYDTLARALSSRSTQAAKVYLTAAPQCPHPDSHLDAALNTGLF 175 Query: 201 AQNLDFVNLMAYDFHGSWEKVTGHNSPLYKRQEESGAAASLNVDAAVQQW--LQKGTPAS 258 ++ Y +S N + + W T A Sbjct: 176 DNV--WIQF-------------------YNNPLAQCQYSSGNTNDILSSWNTWTSSTTAG 214 Query: 259 KLILGMP 265 K+ LG+P Sbjct: 215 KIFLGLP 221 >6BWY-A nrPDB Length = 361 Score = 30.0 bits (66), Expect = 2.4, Method: Composition-based stats. Identities = 5/28 (17%), Positives = 13/28 (46%), Gaps = 1/28 (3%) Query: 207 VNLMAY-DFHGSWEKVTGHNSPLYKRQE 233 +++M Y +F W+ H ++ + Sbjct: 312 ISIMTYSEFKHCWDTFVDHQGAPFQPWD 339 >3V4J-A nrPDB Length = 207 Score = 30.0 bits (66), Expect = 2.4, Method: Composition-based stats. Identities = 5/28 (17%), Positives = 13/28 (46%), Gaps = 1/28 (3%) Query: 207 VNLMAY-DFHGSWEKVTGHNSPLYKRQE 233 +++M Y +F W+ H ++ + Sbjct: 158 ISIMTYSEFKHCWDTFVDHQGAPFQPWD 185 >6BUX-A nrPDB Length = 199 Score = 30.0 bits (66), Expect = 2.4, Method: Composition-based stats. Identities = 5/28 (17%), Positives = 13/28 (46%), Gaps = 1/28 (3%) Query: 207 VNLMAY-DFHGSWEKVTGHNSPLYKRQE 233 +++M Y +F W+ H ++ + Sbjct: 150 ISIMTYSEFKHCWDTFVDHQGAPFQPWD 177 >1E5Q-A nrPDB Length = 450 Score = 28.8 bits (63), Expect = 4.9, Method: Composition-based stats. Identities = 13/72 (18%), Positives = 24/72 (33%) Query: 275 SSSDTRVGAPATGSGTPGPFTKEGGMLAYYEVCSWKGATKQRIQDQKVPYIFRDNQWVGF 334 SSD +G + S Y + A + + K +I+ +V + Sbjct: 162 ESSDNPLGYKFSWSSRGVLLALRNAASFYKDGKVTNVAGPELMATAKPYFIYPGFAFVAY 221 Query: 335 DDVESFKTKVSY 346 + +S K Y Sbjct: 222 PNRDSTPYKERY 233 >3UU2-A nrPDB Length = 357 Score = 28.8 bits (63), Expect = 5.7, Method: Composition-based stats. Identities = 19/108 (17%), Positives = 31/108 (28%), Gaps = 14/108 (12%) Query: 92 TLLAIGGWNFGTQKFTDMVATANNRQTFVNSAIRFLRKYSF----DGLDLDWEYPGSQGS 147 L GG +G F R F DGLD +Y G GS Sbjct: 106 VLPEFGGDTYGADNFMQQRGNG----------YATYRNTDFFGLVDGLDFALQYQGKNGS 155 Query: 148 PAVDKERFTTLVQDLANAFQQEAQTSGKERLLLSAAVPAGQTYVDAGY 195 + + +L+ + + + E + A+ + D Sbjct: 156 VSGENTNGRSLLNQNGDGYGGSLTYAIGEGFSVGGAITTSKRTADQNN 203 >2VY0-A nrPDB Length = 264 Score = 28.8 bits (63), Expect = 5.7, Method: Composition-based stats. Identities = 13/92 (14%), Positives = 30/92 (32%), Gaps = 6/92 (6%) Query: 271 FTLASSSDTRVGAPATGSGTPGPFTKEGGMLAYYEVCSWKGATKQRIQDQKVPYIFRDNQ 330 +T + G P G+G +T+ + + ++ +++ ++ Sbjct: 31 WTFEKGNGIAYGIPGWGNGELEYYTENNTYIVNGTLVIEARKEIITDPNEGT-FLYTSSR 89 Query: 331 W-----VGFDDVESFKTKVSYLKQKGLGGAMV 357 V F + ++ K KGL A Sbjct: 90 LKTEGKVEFSPPVVVEARIKLPKGKGLWPAFW 121 >1KQY-A nrPDB Length = 273 Score = 28.5 bits (62), Expect = 6.1, Method: Composition-based stats. Identities = 9/24 (37%), Positives = 13/24 (54%) Query: 348 KQKGLGGAMVWALDLDDFAGFSCN 371 K GG M+W+ DD G+S + Sbjct: 245 KSPKYGGVMLWSKFYDDKNGYSSS 268 >5WTL-A nrPDB Length = 261 Score = 28.1 bits (61), Expect = 7.8, Method: Composition-based stats. Identities = 10/34 (29%), Positives = 13/34 (38%) Query: 280 RVGAPATGSGTPGPFTKEGGMLAYYEVCSWKGAT 313 V PA G P P T G+L ++C Sbjct: 100 DVAGPAENGGCPWPDTDGDGVLDKDDLCPEVAGP 133 >5LA1-A nrPDB Length = 491 Score = 28.1 bits (61), Expect = 7.8, Method: Composition-based stats. Identities = 14/73 (19%), Positives = 22/73 (30%), Gaps = 7/73 (9%) Query: 282 GAPATGSGTPGPFTKEGGMLAYYEVCSWKG---ATKQRIQDQKVPYIFRDNQWVGFDDVE 338 P G+ G LA E +W RI+ + + V + D + Sbjct: 306 WTPDYGNWPAARGVYGNGGLA-RETATWINNFLTGTTRIEAEDFDW---GGNGVSYYDTD 361 Query: 339 SFKTKVSYLKQKG 351 S Y +G Sbjct: 362 SVNVGGQYRPDEG 374 >5G56-A nrPDB Length = 862 Score = 28.1 bits (61), Expect = 8.6, Method: Composition-based stats. Identities = 14/73 (19%), Positives = 22/73 (30%), Gaps = 7/73 (9%) Query: 282 GAPATGSGTPGPFTKEGGMLAYYEVCSWKG---ATKQRIQDQKVPYIFRDNQWVGFDDVE 338 P G+ G LA E +W RI+ + + V + D + Sbjct: 304 WTPDYGNWPAARGVYGNGGLA-RETATWINNFLTGTTRIEAEDFDW---GGNGVSYYDTD 359 Query: 339 SFKTKVSYLKQKG 351 S Y +G Sbjct: 360 SVNVGGQYRPDEG 372 >3OIS-A nrPDB Length = 291 Score = 28.1 bits (61), Expect = 8.8, Method: Composition-based stats. Identities = 10/53 (18%), Positives = 20/53 (37%) Query: 381 LRQELSLPYLPSGTPELEVPKPGQPSEPEHGPSPGQDTFCQGKADGLYPNPRE 433 +R + + + PE E P P++P P + +D Y + + Sbjct: 126 IRDGIKVLHKLGVCPEKEWPYGDTPADPRTEEFPPGAPASKKPSDQCYKDAQN 178 >1V5D-A nrPDB Length = 386 Score = 28.1 bits (61), Expect = 9.4, Method: Composition-based stats. Identities = 11/91 (12%), Positives = 24/91 (26%), Gaps = 6/91 (6%) Query: 212 YDFHGSWEKVTGHNSPLY-----KRQEESGAAASLN-VDAAVQQWLQKGTPASKLILGMP 265 YD + + N+ L K + L+ + + ++++ Sbjct: 225 YDVYTQFSNKYSPNTGLISDFVVKNPPQPAPKDFLDESEYTNAYYYNASRVPLRIVMDYA 284 Query: 266 TYGRSFTLASSSDTRVGAPATGSGTPGPFTK 296 YG + S +G P Sbjct: 285 MYGEKRSKVISDKVSSWIQNKTNGNPSKIVD 315 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.308 0.137 0.414 Lambda K H 0.267 0.0423 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 19,968,509 Number of Sequences: 36641 Number of extensions: 847075 Number of successful extensions: 2922 Number of sequences better than 10.0: 91 Number of HSP's better than 10.0 without gapping: 125 Number of HSP's successfully gapped in prelim test: 38 Number of HSP's that attempted gapping in prelim test: 2273 Number of HSP's gapped (non-prelim): 208 length of query: 466 length of database: 10,336,785 effective HSP length: 101 effective length of query: 365 effective length of database: 6,636,044 effective search space: 2422156060 effective search space used: 2422156060 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.1 bits) S2: 61 (28.1 bits)