BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q13144 (721 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 6O85-A nrPDB 1497 0.0 6JLY-I nrPDB 375 e-104 6I7T-G nrPDB 294 7e-80 5B04-E nrPDB 70 3e-12 6EZO-E nrPDB 48 2e-05 4Y7U-A nrPDB 47 4e-05 2OI7-A nrPDB 40 0.003 1FWY-A nrPDB 40 0.004 3TWD-A nrPDB 40 0.004 5J49-A nrPDB 40 0.005 6I7T-I nrPDB 40 0.005 5VE7-A nrPDB 40 0.005 5Z09-A nrPDB 39 0.005 4IHG-A nrPDB 37 0.021 5I1F-A nrPDB 37 0.039 1JYL-A nrPDB 37 0.044 4MFG-A nrPDB 36 0.058 5XHW-A nrPDB 35 0.14 4D48-A nrPDB 34 0.19 2UX8-A nrPDB 34 0.21 5MNI-E nrPDB 34 0.22 2E3D-A nrPDB 34 0.22 1YP3-A nrPDB 34 0.27 3JUK-A nrPDB 34 0.28 1HM0-A nrPDB 33 0.32 3FWW-A nrPDB 33 0.38 6F3A-U nrPDB 33 0.53 1LVW-A nrPDB 33 0.62 1MC3-A nrPDB 32 0.93 3PMO-A nrPDB 32 0.97 2V0L-A nrPDB 31 1.6 6FYY-m nrPDB 31 2.1 5VI4-A nrPDB 30 2.6 1OCX-A nrPDB 30 3.2 3Q1X-A nrPDB 30 3.5 1J2Z-A nrPDB 30 3.9 5VMK-A nrPDB 30 5.4 3CJ8-A nrPDB 29 7.5 3TIO-A nrPDB 29 8.7 >6O85-A nrPDB Length = 721 Score = 1497 bits (3876), Expect = 0.0, Method: Compositional matrix adjust. Identities = 721/721 (100%), Positives = 721/721 (100%) Query: 1 MAAPVVAPPGVVVSRANKRSGAGPGGSGGGGARGAEEEPPPPLQAVLVADSFDRRFFPIS 60 MAAPVVAPPGVVVSRANKRSGAGPGGSGGGGARGAEEEPPPPLQAVLVADSFDRRFFPIS Sbjct: 1 MAAPVVAPPGVVVSRANKRSGAGPGGSGGGGARGAEEEPPPPLQAVLVADSFDRRFFPIS 60 Query: 61 KDQPRVLLPLANVALIDYTLEFLTATGVQETFVFCCWKAAQIKEHLLKSKWCRPTSLNVV 120 KDQPRVLLPLANVALIDYTLEFLTATGVQETFVFCCWKAAQIKEHLLKSKWCRPTSLNVV Sbjct: 61 KDQPRVLLPLANVALIDYTLEFLTATGVQETFVFCCWKAAQIKEHLLKSKWCRPTSLNVV 120 Query: 121 RIITSELYRSLGDVLRDVDAKALVRSDFLLVYGDVISNINITRALEEHRLRRKLEKNVSV 180 RIITSELYRSLGDVLRDVDAKALVRSDFLLVYGDVISNINITRALEEHRLRRKLEKNVSV Sbjct: 121 RIITSELYRSLGDVLRDVDAKALVRSDFLLVYGDVISNINITRALEEHRLRRKLEKNVSV 180 Query: 181 MTMIFKESSPSHPTRCHEDNVVVAVDSTTNRVLHFQKTQGLRRFAFPLSLFQGSSDGVEV 240 MTMIFKESSPSHPTRCHEDNVVVAVDSTTNRVLHFQKTQGLRRFAFPLSLFQGSSDGVEV Sbjct: 181 MTMIFKESSPSHPTRCHEDNVVVAVDSTTNRVLHFQKTQGLRRFAFPLSLFQGSSDGVEV 240 Query: 241 RYDLLDCHISICSPQVAQLFTDNFDYQTRDDFVRGLLVNEEILGNQIHMHVTAKEYGARV 300 RYDLLDCHISICSPQVAQLFTDNFDYQTRDDFVRGLLVNEEILGNQIHMHVTAKEYGARV Sbjct: 241 RYDLLDCHISICSPQVAQLFTDNFDYQTRDDFVRGLLVNEEILGNQIHMHVTAKEYGARV 300 Query: 301 SNLHMYSAVCADVIRRWVYPLTPEANFTDSTTQSCTHSRHNIYRGPEVSLGHGSILEENV 360 SNLHMYSAVCADVIRRWVYPLTPEANFTDSTTQSCTHSRHNIYRGPEVSLGHGSILEENV Sbjct: 301 SNLHMYSAVCADVIRRWVYPLTPEANFTDSTTQSCTHSRHNIYRGPEVSLGHGSILEENV 360 Query: 361 LLGSGTVIGSNCFITNSVIGPGCHIGDNVVLDQTYLWQGVRVAAGAQIHQSLLCDNAEVK 420 LLGSGTVIGSNCFITNSVIGPGCHIGDNVVLDQTYLWQGVRVAAGAQIHQSLLCDNAEVK Sbjct: 361 LLGSGTVIGSNCFITNSVIGPGCHIGDNVVLDQTYLWQGVRVAAGAQIHQSLLCDNAEVK 420 Query: 421 ERVTLKPRSVLTSQVVVGPNITLPEGSVISLHPPDAEEDEDDGEFSDDSGADQEKDKVKM 480 ERVTLKPRSVLTSQVVVGPNITLPEGSVISLHPPDAEEDEDDGEFSDDSGADQEKDKVKM Sbjct: 421 ERVTLKPRSVLTSQVVVGPNITLPEGSVISLHPPDAEEDEDDGEFSDDSGADQEKDKVKM 480 Query: 481 KGYNPAEVGAAGKGYLWKAAGMNMEEEEELQQNLWGLKINMEEESESESEQSMDSEEPDS 540 KGYNPAEVGAAGKGYLWKAAGMNMEEEEELQQNLWGLKINMEEESESESEQSMDSEEPDS Sbjct: 481 KGYNPAEVGAAGKGYLWKAAGMNMEEEEELQQNLWGLKINMEEESESESEQSMDSEEPDS 540 Query: 541 RGGSPQMDDIKVFQNEVLGTLQRGKEENISCDNLVLEINSLKYAYNISLKEVMQVLSHVV 600 RGGSPQMDDIKVFQNEVLGTLQRGKEENISCDNLVLEINSLKYAYNISLKEVMQVLSHVV Sbjct: 541 RGGSPQMDDIKVFQNEVLGTLQRGKEENISCDNLVLEINSLKYAYNISLKEVMQVLSHVV 600 Query: 601 LEFPLQQMDSPLDSSRYCALLLPLLKAWSPVFRNYIKRAADHLEALAAIEDFFLEHEALG 660 LEFPLQQMDSPLDSSRYCALLLPLLKAWSPVFRNYIKRAADHLEALAAIEDFFLEHEALG Sbjct: 601 LEFPLQQMDSPLDSSRYCALLLPLLKAWSPVFRNYIKRAADHLEALAAIEDFFLEHEALG 660 Query: 661 ISMAKVLMAFYQLEILAEETILSWFSQRDTTDKGQQLRKNQQLQRFIQWLKEAEEESSED 720 ISMAKVLMAFYQLEILAEETILSWFSQRDTTDKGQQLRKNQQLQRFIQWLKEAEEESSED Sbjct: 661 ISMAKVLMAFYQLEILAEETILSWFSQRDTTDKGQQLRKNQQLQRFIQWLKEAEEESSED 720 Query: 721 D 721 D Sbjct: 721 D 721 >6JLY-I nrPDB Length = 678 Score = 375 bits (964), Expect = e-104, Method: Compositional matrix adjust. Identities = 232/693 (33%), Positives = 371/693 (53%), Gaps = 41/693 (5%) Query: 31 GARGAEEEPPPPLQAVLVADSFDRRFFPISKDQPRVLLPLANVALIDYTLEFLTATGVQE 90 G G E+P LQA++++DS++ RF P++ D+PR LLPLAN LI+YT EFL GVQE Sbjct: 6 GLNGKLEKPKHALQAIVLSDSYNYRFRPLTLDKPRCLLPLANTPLIEYTFEFLALAGVQE 65 Query: 91 TFVFCCWKAAQIKEHLLKSKWCRPTSLNVVRIITSELYRSLGDVLRDVDAKALVRSDFLL 150 +VFCC A QI+E++ KSKW P+S V I S S+GD LR++D+K L+ SDF+L Sbjct: 66 VYVFCCAHAGQIREYIEKSKWNLPSSPFSVNTIVSRESLSVGDALRELDSKQLITSDFIL 125 Query: 151 VYGDVISNINITRALEEHRLRRKLEKNVSVMTMIFKESSPSHPTRCHEDNVVVAVDSTTN 210 V GDV+SN+ + L+EHR RR+ +KN ++MTM+ +E+SP H TR ++ V +D T+ Sbjct: 126 VSGDVVSNVPLNEVLKEHRKRREDDKN-AIMTMVVREASPFHRTRARTESSVFVIDKKTS 184 Query: 211 RVLHFQKTQGLRRFAFPLSLFQGSSDGVEVRYDLLDCHISICSPQVAQLFTDNFDYQ-TR 269 + +H+Q + + + + +EVR DL+DC I ICS V LFT+NFDYQ R Sbjct: 185 QCVHYQANERGKHYVSMDPEIFNEHEELEVRNDLIDCQIDICSNDVPALFTENFDYQDIR 244 Query: 270 DDFVRGLLVNEEILGNQIHMHVTAKEYGARVSNLHMYSAVCADVIRRWVYPLTPEANFTD 329 DFV G+L + ++LG +IH HV + Y ARV +L Y A+ DV+ RWVYP P++N + Sbjct: 245 KDFVYGVLTS-DLLGKKIHCHVAKENYAARVRSLQTYDAISKDVLSRWVYPFVPDSNLLN 303 Query: 330 STTQSCTHSRHNIYRGPEVSLGHGSILEENVLLGSGTVIGSNCFITNSVIGPGCHIGDNV 389 Q+ ++ RH IY+ +V L I++ L+G+ T +G + N++IG C IG N Sbjct: 304 ---QTFSYQRHQIYKEEDVVLARSCIIKARTLIGAYTKVGDASVVANTIIGRNCTIGSNC 360 Query: 390 VLDQTYLWQGVRVAAGAQIHQSLLCDNAEVKERVTLKPRSVLTSQVVVGPNITLPEGSVI 449 +D +LW+ V + +I +++L ++ ++ +++ +++ + VV+G N + + + Sbjct: 361 SIDSAFLWEDVVIGDNCRIGKAILANSVKIGNNCSIEDGAIVAAGVVIGDNTIIEKNKRL 420 Query: 450 SLHPPDAEEDEDDGEFSDDSGADQEKDKVKMKGYNPAEVGAAGKGYLWKAAGMNMEEEEE 509 + ++ +D G QE AE + +G +A+G+ +E E Sbjct: 421 TTFESHSQGTLNDPSLVGIGGRGQEYH---------AEEDSDDEGEFMEASGL-IESTNE 470 Query: 510 LQQNLWGLKINMEEESESESEQSMD----SEEPDSRGGSPQMD-DIKVFQNEVLGTLQRG 564 L L + E+ S SE+ M+ S DS D D F E +L+R Sbjct: 471 LH-----LSDSESSETSSSSEEDMEFIPFSARRDSANTINSEDFDEGDFNKEAQQSLERA 525 Query: 565 KEENISCDNLVLEINSLKYAYNISLKEVMQVLSHVVLEFPLQQMDSPLDSSRYCALLLPL 624 EEN D LE+N+L+ A N + EV + +L + SP ++ L + Sbjct: 526 FEENHQIDIAALELNTLRMAMNANYHEVRSAIVLALLRRIMHLDVSPKEA------LAKV 579 Query: 625 LKAWSPVFRNYIKRAADHLEALAAIEDFFLEHEALGISMAK----VLMAFYQLEILAEET 680 + W P+ K H E + + L+ + +SM + +L FYQLEI E Sbjct: 580 MTRWGPLL---AKLTFSHEEQVDNV--LTLQKYCVRLSMTRHFLQLLGYFYQLEIAEENA 634 Query: 681 ILSWFSQRDTTDKGQQLRKNQQLQRFIQWLKEA 713 I W+S +++ ++ ++F+ WL A Sbjct: 635 IQEWYSDPRSSEGELAALRDAGGKQFVDWLNTA 667 >6I7T-G nrPDB Length = 712 Score = 294 bits (753), Expect = 7e-80, Method: Compositional matrix adjust. Identities = 209/732 (28%), Positives = 360/732 (49%), Gaps = 64/732 (8%) Query: 15 RANKRSGAGPGGSGGGGARGAEEEPPPPLQAVLVADSFDRRFFPISKDQPRVLLPLANVA 74 + K+SG G G + ++ + LQAV++ DS++ RF P++ +PR LLPLANV Sbjct: 5 KGQKKSGLGNHG------KNSDMDVEDRLQAVVLTDSYETRFMPLTAVKPRCLLPLANVP 58 Query: 75 LIDYTLEFLTATGVQETFVFCCWKAAQIKEHLLKSKWCRPTSLNVVRIITSELYRSLGDV 134 LI+YTLEFL GV E F+ C A QI +++ SKW P S + I S R GDV Sbjct: 59 LIEYTLEFLAKAGVHEVFLICSSHANQINDYIENSKWNLPWSPFKITTIMSPEARCTGDV 118 Query: 135 LRDVDAKALVRSDFLLVYGDVISNINITRALEEHRLRRKLEKNVSVMTMIFKESSPSHPT 194 +RD+D + ++ DF+LV GDV++NI+ ++ LE H+ + L+ + TM ++S T Sbjct: 119 MRDLDNRGIITGDFILVSGDVLTNIDFSKMLEFHK-KMHLQDKDHISTMCLSKASTYPKT 177 Query: 195 RCHEDNVVVAVDSTTNRVLHFQKTQGLRRFAFPLSLFQGS----------SDGVEVRYDL 244 R E V +D +T+R +++Q P S + S D +R DL Sbjct: 178 RTIEPAAFV-LDKSTSRCIYYQD------LPLPSSREKTSIQIDPELLDNVDEFVIRNDL 230 Query: 245 LDCHISICSPQVAQLFTDNFDYQT-RDDFVRGLLVNEEILGNQIHMHVTAKEYGARVSNL 303 +DC I IC+ V +F +NFDYQ+ R DFV+G +++ +ILG I+ ++T EY RV + Sbjct: 231 IDCRIDICTSHVPLIFQENFDYQSLRTDFVKG-VISSDILGKHIYAYLT-DEYAVRVESW 288 Query: 304 HMYSAVCADVIRRWVYPLTPEANFTDSTTQSCTHSRHNIYRGPEVSLGHGSILEENVLLG 363 Y + D + RW YPL ++N D T S SRH IY+ +V L + + +G Sbjct: 289 QTYDTISQDFLGRWCYPLVLDSNIQDDQTYS-YESRH-IYKEKDVVLAQSCKIGKCTAIG 346 Query: 364 SGTVIGSNCFITNSVIGPGCHIGDNVVLDQTYLWQGVRVAAGAQIHQSLLCDNAEVKERV 423 SGT IG I NSVIG C IG+N+ + +++W + + I SL+ NA + V Sbjct: 347 SGTKIGEGTKIENSVIGRNCQIGENIRIKNSFIWDDCIIGNNSIIDHSLIASNATLGSNV 406 Query: 424 TLKPRSVLTSQVVVGPNITLPEGSVISLHP-PDAEEDEDDGEFSDDSGADQEKDKVKMKG 482 L ++ V + N+ L + IS P +A D E ++ D + + + Sbjct: 407 RLNDGCIIGFNVKIDDNMDLDRNTKISASPLKNAGSRMYDNESNEQFDQDLDDQTLAV-- 464 Query: 483 YNPAEVGAAGKGYLWKAAGMNMEEEE-ELQQNLWGLKINMEEESESESEQSMDSEEPDSR 541 + VG G GY++++ + E+ E + + L ++E S+ S +++ R Sbjct: 465 ---SIVGDKGVGYIYESEVSDDEDSSTEACKEINTLSNQLDELYLSDDSISSATKKTKKR 521 Query: 542 GGSPQMDDIKVFQNEV-------------LGTLQRGKEENISCDNLVLEINSLKYAYNIS 588 + ++ I + E+ + T++R E N D +LE+N+L+ + N++ Sbjct: 522 -RTMSVNSIYTDREEIDSEFEDEDFEKEGIATVERAMENNHDLDTALLELNTLRMSMNVT 580 Query: 589 LKEV----MQVLSHVVLEFPLQQMDSPLDSSRYCALLLPLLKAWSPVFRNYIKRAADHLE 644 EV + L V F Q P D+ ++ + W +F+ ++++ Sbjct: 581 YHEVRIATITALLRRVYHFIATQTLGPKDA------VVKVFNQWGLLFKRQAFDEEEYID 634 Query: 645 ALAAIEDFFLEH--EALGISMAKVLMAFYQLEILAEETILSWFSQRDTTDKGQQLRKNQQ 702 + I + +E + + + L++ Y +I+ E+ I W+ T + +++K Sbjct: 635 LMNIIMEKIVEQSFDKPDLILFSALVSLYDNDIIEEDVIYKWWDNVSTDPRYDEVKK--L 692 Query: 703 LQRFIQWLKEAE 714 ++++WL+ A+ Sbjct: 693 TVKWVEWLQNAD 704 >5B04-E nrPDB Length = 458 Score = 70.1 bits (170), Expect = 3e-12, Method: Compositional matrix adjust. Identities = 93/437 (21%), Positives = 173/437 (39%), Gaps = 64/437 (14%) Query: 25 GGSGGGGARG--AEEEPPPPLQAVLVADSFDRRFFPISKDQ--PRVLLPLANVALIDYTL 80 G GG RG + P QAV+ A F +P++ P+ LLP+ N ++ Y L Sbjct: 19 GPISGGRNRGNIQLQSIPIEFQAVVFA-GFGNSLYPLTGSDALPKALLPIGNKPMLHYPL 77 Query: 81 EFLTATGVQETFVFCCWKAAQIKEHLLKSKWCRPTSLNVVRIITSELYRSLGDVLRDVDA 140 +L A G + C +A L+S + ++V + +S D LR V Sbjct: 78 YWLEAAGFTSAILICMEEAEAHINAWLRSGYEGHMRIHVEAPTILDDSKSSADALRAV-- 135 Query: 141 KALVRSDFLLVYGDVISNINITRALEEHRLRRKLEKNVSVMTMIFKESSPSHPTRCHEDN 200 L+++DF+ + D I + L++ RL ++V + + K + ++ + Sbjct: 136 SHLIKNDFVCLSCDSIVGLPPYTVLDKFRLDNP--SALAVYSPVLKYEHITSQSKEIDAK 193 Query: 201 VVVAVDSTTNRVLHFQKTQGL-RRFAFPLSLFQGSSDGVEVRYDLLDCHISICSPQVAQL 259 ++ ++ T+R+L+ + + + F F +SL V + +L D HI + V L Sbjct: 194 QLIGIEEKTSRLLYAKSSADVGSDFTFRMSLLWKHPR-VTLNTNLSDAHIFVFKHWVIDL 252 Query: 260 FT----------DNFDYQTRDDFVRGLLVNEEI----------------LGNQ-IHMHVT 292 D Y + + + V E I L +Q I ++ Sbjct: 253 IREKESISSIRGDLIPYLVKCQYQKSFTVRENIQRFLSSPNNIDNYDGGLSSQEIKINAL 312 Query: 293 AKEYG---ARVSNLHMYSAVCADVIRRWVYPLTPEANFTDSTTQSCTHSRHNIYRGPEVS 349 + G +R +NL Y + + + LTPE D V+ Sbjct: 313 IAKDGIICSRANNLPNYFE-----LNKCIAKLTPEQRLVD------------------VT 349 Query: 350 LGHGSILEENVLLGSGTVIGSNCFITNSVIGPGCHIGDNVVLDQTYLWQGVRVAAGAQIH 409 + +++ + ++ GT I N I S+IG C IG VV+ + L + V G ++ Sbjct: 350 VSERALVGADCMVNEGTTIKDNSNIKKSIIGKNCVIGKGVVVSNSILMDNIVVEDGVRLE 409 Query: 410 QSLLCDNAEVKERVTLK 426 ++ A++ + L+ Sbjct: 410 SCIVASGAQIGAKSKLR 426 >6EZO-E nrPDB Length = 452 Score = 47.8 bits (112), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 38/141 (26%), Positives = 62/141 (43%), Gaps = 17/141 (12%) Query: 286 QIHMHVTAKEYGARVSNLHMYSAVCADVIRRWVYPLTPEANFTDSTTQSCTHSRHNIYRG 345 + ++H+ + +RVS L +Y V + + L PE S+ Q S+H Sbjct: 299 RCYVHIMKEGLCSRVSTLGLYMEANRQV-PKLLSALCPEEPPVHSSAQ--IVSKH----- 350 Query: 346 PEVSLGHGSILEENVLLGSGTVIGSNCFITNSVIGPGCHIGDNVVLDQTYLWQGVRVAAG 405 ++ + L+G T IG I SVIG C I D V + L V V G Sbjct: 351 ---------LVGVDSLIGPETQIGEKSSIKRSVIGSSCLIKDRVTITNCLLMNSVTVEEG 401 Query: 406 AQIHQSLLCDNAEVKERVTLK 426 + I S++C+NA +++ +K Sbjct: 402 SNIQGSVICNNAVIEKGADIK 422 Score = 35.4 bits (80), Expect = 0.086, Method: Compositional matrix adjust. Identities = 41/183 (22%), Positives = 77/183 (42%), Gaps = 25/183 (13%) Query: 43 LQAVLVADSFDRRFFPISKDQPRVLLPLANVALIDYTLEFLTATGVQETFVFCCWK---- 98 QAV++A R ++ P+ LLP+ N LI Y L L G +E V Sbjct: 3 FQAVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTTRDVQKA 62 Query: 99 -AAQIKEHLLKSKWCRPTSLNVVRIITSELYRSLGDVLRDVDAKALVRSDFLLVYGDVIS 157 A+ K + C P ++ D LR + K +++D L++ D+I+ Sbjct: 63 LCAEFKMKMKPDIVCIPDDADM----------GTADSLRYIYPK--LKTDVLVLSCDLIT 110 Query: 158 NINITRALEEHRLRRKLEKNVSVMTMIFKESSPSHPTRCHEDNVV-----VAVDSTTNRV 212 ++ + ++ L R + +++++ ++S P + + V + VDST R+ Sbjct: 111 DVALHEVVD---LFRAYDASLAMLMRKGQDSIEPVPGQKGKKKAVEQRDFIGVDSTGKRL 167 Query: 213 LHF 215 L Sbjct: 168 LFM 170 >4Y7U-A nrPDB Length = 231 Score = 46.6 bits (109), Expect = 4e-05, Method: Composition-based stats. Identities = 34/121 (28%), Positives = 58/121 (47%), Gaps = 5/121 (4%) Query: 43 LQAVLVADSFDRRFFPISKDQPRVLLPLANVALIDYTLEFLTATGVQETFVFCCWKAAQI 102 ++A+++A R P++ P+ L+P+A LI+Y L L A GV E + W QI Sbjct: 1 MKAMILAAGKGERMRPLTLHTPKPLVPVAGQPLIEYHLRALAAAGVTEVVINHAWLGQQI 60 Query: 103 KEHLLKSKWCRPTSLNVVRIITSELYRSLGDVLRDVDAKALVRSDFLLVYGDVISNINIT 162 ++HL L++ E + G + + + L + FLLV GDV ++ + Sbjct: 61 EDHLGDGS---RFGLSIRYSPEGEPLETGGGIFKAL--PLLGDAPFLLVNGDVWTDYDFA 115 Query: 163 R 163 R Sbjct: 116 R 116 >2OI7-A nrPDB Length = 456 Score = 40.0 bits (92), Expect = 0.003, Method: Compositional matrix adjust. Identities = 28/89 (31%), Positives = 40/89 (44%), Gaps = 1/89 (1%) Query: 339 RHNIYRGPEVSLGHGSILEENVLLGSGTVIGSNCFITNSVIGPGCHIGDNVVLDQTYLWQ 398 R + G +V + I+E NV LG IG+ C I NSVIG C I V++ L Sbjct: 263 RGTLTHGRDVEIDTNVIIEGNVTLGHRVKIGTGCVIKNSVIGDDCEISPYTVVEDANLAA 322 Query: 399 GVRVAAGAQIHQSL-LCDNAEVKERVTLK 426 + A++ L + A V V +K Sbjct: 323 ACTIGPFARLRPGAELLEGAHVGNFVEMK 351 >1FWY-A nrPDB Length = 331 Score = 40.0 bits (92), Expect = 0.004, Method: Compositional matrix adjust. Identities = 22/58 (37%), Positives = 29/58 (50%) Query: 339 RHNIYRGPEVSLGHGSILEENVLLGSGTVIGSNCFITNSVIGPGCHIGDNVVLDQTYL 396 R + G +V + I+E NV LG IG+ C I NSVIG C I V++ L Sbjct: 263 RGTLTHGRDVEIDTNVIIEGNVTLGHRVKIGTGCVIKNSVIGDDCEISPYTVVEDANL 320 >3TWD-A nrPDB Length = 222 Score = 39.7 bits (91), Expect = 0.004, Method: Compositional matrix adjust. Identities = 28/89 (31%), Positives = 40/89 (44%), Gaps = 1/89 (1%) Query: 339 RHNIYRGPEVSLGHGSILEENVLLGSGTVIGSNCFITNSVIGPGCHIGDNVVLDQTYLWQ 398 R + G +V + I+E NV LG IG+ C I NSVIG C I V++ L Sbjct: 32 RGTLTHGRDVEIDTNVIIEGNVTLGHRVKIGTGCVIKNSVIGDDCEISPYTVVEDANLAA 91 Query: 399 GVRVAAGAQIHQSL-LCDNAEVKERVTLK 426 + A++ L + A V V +K Sbjct: 92 ACTIGPFARLRPGAELLEGAHVGNFVEMK 120 >5J49-A nrPDB Length = 301 Score = 39.7 bits (91), Expect = 0.005, Method: Compositional matrix adjust. Identities = 20/66 (30%), Positives = 30/66 (45%) Query: 44 QAVLVADSFDRRFFPISKDQPRVLLPLANVALIDYTLEFLTATGVQETFVFCCWKAAQIK 103 +AV RF P +K P+ +LP+ + LI Y +E A G+ E I+ Sbjct: 14 KAVFPVAGLGTRFLPATKASPKEMLPIVDKPLIQYAVEEAMAAGITEMIFVTGRSKRAIE 73 Query: 104 EHLLKS 109 +H KS Sbjct: 74 DHFDKS 79 >6I7T-I nrPDB Length = 578 Score = 39.7 bits (91), Expect = 0.005, Method: Compositional matrix adjust. Identities = 36/171 (21%), Positives = 72/171 (42%), Gaps = 27/171 (15%) Query: 299 RVSNLHMYSAVCADVIRRWVYPLTPEANFTDSTTQSCTHSRHNIYRGPEVSLGHGSILEE 358 R +NL+ Y R+V + + FT + + P+ + S ++ Sbjct: 394 RANNLNAYMDA-----NRFVLKIKSQTMFTKNIQIQSAAIGADAIVDPKCQISAHSNVKM 448 Query: 359 NVLLGSGTVIGSNCFITNSVIGPGCHIGDNVVLDQTYLWQGVRVAAGAQIHQSLLCDNAE 418 +VL G+ IGS C + S++ PG H+GD V+L+ + ++ + ++ N Sbjct: 449 SVL-GTQANIGSRCRVAGSLLFPGVHLGDEVILENCIIGPMAKIGSKCKL------SNCY 501 Query: 419 VKERVTLKPRSVLTSQVVVGPNITLPEGSVISLHPPDAEEDEDDGEFSDDS 469 ++ ++P++ + + N+ L +EDE+D DDS Sbjct: 502 IEGHYVVEPKNNFKGETLA--NVYL-------------DEDEEDELIYDDS 537 >5VE7-A nrPDB Length = 302 Score = 39.7 bits (91), Expect = 0.005, Method: Compositional matrix adjust. Identities = 20/66 (30%), Positives = 30/66 (45%) Query: 44 QAVLVADSFDRRFFPISKDQPRVLLPLANVALIDYTLEFLTATGVQETFVFCCWKAAQIK 103 +AV RF P +K P+ +LP+ + LI Y +E A G+ E I+ Sbjct: 14 KAVFPVAGLGTRFLPATKASPKEMLPVVDKPLIQYAVEEAIAAGITEMIFVTGRSKRAIE 73 Query: 104 EHLLKS 109 +H KS Sbjct: 74 DHFDKS 79 >5Z09-A nrPDB Length = 409 Score = 39.3 bits (90), Expect = 0.005, Method: Compositional matrix adjust. Identities = 18/66 (27%), Positives = 35/66 (53%) Query: 43 LQAVLVADSFDRRFFPISKDQPRVLLPLANVALIDYTLEFLTATGVQETFVFCCWKAAQI 102 ++A ++A R PI+ +P+ +P+ + LI+Y +E+L G+++ V K + Sbjct: 1 MKAFILAAGSGERLEPITHTRPKAFVPILSKPLIEYQIEYLRKCGIRDITVIVSSKNKEY 60 Query: 103 KEHLLK 108 E LK Sbjct: 61 FEKKLK 66 Score = 30.0 bits (66), Expect = 3.6, Method: Compositional matrix adjust. Identities = 37/152 (24%), Positives = 62/152 (40%), Gaps = 24/152 (15%) Query: 329 DSTTQSCTHSRHNIYRGPEVSLGHGSILEENVLLGSGTVIGSNCFITNSVIGPG------ 382 D+ +S T+ +Y G +G S L +L IG++ + SVI G Sbjct: 250 DAEIKSGTYIEGPVYIGKGSEIGPNSYLRPYTILVEKNKIGASVEVKESVIMEGSKIPHL 309 Query: 383 CHIGDNVVLDQTYLWQGVRVAAGAQIHQSLLCDNAEVK-----ERVTLKPRSV---LTSQ 434 ++GD+V+ + G +A +L D EVK +R++ R + + Sbjct: 310 SYVGDSVIAEDVNFGAGTLIA-------NLRFDEKEVKVNVKGKRISSGRRKLGAFIGGH 362 Query: 435 VVVGPNITLPEGSVISLHP---PDAEEDEDDG 463 V G N+T+ G I + P A + D G Sbjct: 363 VRTGINVTILPGVKIGAYARIYPGAVVNRDVG 394 >4IHG-A nrPDB Length = 348 Score = 37.4 bits (85), Expect = 0.021, Method: Compositional matrix adjust. Identities = 25/76 (32%), Positives = 36/76 (47%), Gaps = 12/76 (15%) Query: 345 GPEVSLGHGSILEENVLLGSGTVIGSNCFI-TNSVIGPGCHIGDNVVLDQTYLWQGVRVA 403 G VS+G +++E V LG +IG+ CF+ NS IG G + LW V + Sbjct: 120 GNNVSIGANAVIESGVELGDNVIIGAGCFVGKNSKIGAG-----------SRLWANVTIY 168 Query: 404 AGAQIHQSLLCDNAEV 419 QI Q+ L + V Sbjct: 169 HEIQIGQNCLIQSGTV 184 Score = 28.9 bits (63), Expect = 8.5, Method: Compositional matrix adjust. Identities = 33/126 (26%), Positives = 52/126 (41%), Gaps = 26/126 (20%) Query: 347 EVSLGHGSILEENVLLGSGTVIGSNCF--------------ITNSVIGPGCHIG-----D 387 V++ H + +N L+ SGTV+G++ F I +IG IG D Sbjct: 164 NVTIYHEIQIGQNCLIQSGTVVGADGFGYANDRGNWVKIPQIGRVIIGDRVEIGACTTID 223 Query: 388 NVVLDQTYLWQGVRVAAGAQI-HQSLLCDNAEVKERVTLKPRSVLTSQVVVGPNITLPEG 446 LD T + GV + QI H ++ DN V V ++ + +G + Sbjct: 224 RGALDDTIIGNGVIIDNQCQIAHNVVIGDNTAVAGGV------IMAGSLKIGRYCMIGGA 277 Query: 447 SVISLH 452 SVI+ H Sbjct: 278 SVINGH 283 >5I1F-A nrPDB Length = 302 Score = 36.6 bits (83), Expect = 0.039, Method: Compositional matrix adjust. Identities = 19/66 (28%), Positives = 29/66 (43%) Query: 44 QAVLVADSFDRRFFPISKDQPRVLLPLANVALIDYTLEFLTATGVQETFVFCCWKAAQIK 103 +AV RF P +K P+ +LP+ + LI Y +E G+ E I+ Sbjct: 14 KAVFPVAGLGTRFLPATKASPKEMLPVVDKPLIQYAVEEAIEAGITEMIFVTGRSKRAIE 73 Query: 104 EHLLKS 109 +H KS Sbjct: 74 DHFDKS 79 >1JYL-A nrPDB Length = 254 Score = 36.6 bits (83), Expect = 0.044, Method: Compositional matrix adjust. Identities = 17/69 (24%), Positives = 36/69 (52%), Gaps = 2/69 (2%) Query: 43 LQAVLVADSFDRRFFPISKDQPRVLLPLANVALIDYTLEFLTATGVQETFVFCCWKAAQI 102 ++A+++A R P++++ P+ L+ + LI+Y +EFL G+ + + + Q Sbjct: 26 VKAIILAAGLGTRLRPLTENTPKALVQVNQKPLIEYQIEFLKEKGINDIIIIVGYLKEQF 85 Query: 103 KEHLLKSKW 111 LK K+ Sbjct: 86 --DYLKEKY 92 >4MFG-A nrPDB Length = 168 Score = 36.2 bits (82), Expect = 0.058, Method: Composition-based stats. Identities = 33/134 (24%), Positives = 62/134 (46%), Gaps = 28/134 (20%) Query: 342 IYRGPE--VSLGHGSILEENVLL--GSGTVIGSNCFITNSVIGPGCHIGDNVVLDQTYLW 397 + RG E +++G + +++ ++ + T+IG+N + + I GC I DNV++ Sbjct: 44 VVRGDEGPITIGENTNIQDCSIVHGDTETIIGNNVTVGHRSIVHGCKISDNVLIGMG--- 100 Query: 398 QGVRVAAGAQIHQSLLCDNAEVKERVTLKPRSVLTSQVVVGPNITLPEGSVISLHPPDA- 456 S++ DNAE+ E + +++TS N P G +I P Sbjct: 101 -------------SIILDNAEIGEYTLIGAGTLITS------NKKFPPGVLIMGSPGKVV 141 Query: 457 -EEDEDDGEFSDDS 469 E E+D ++ D+S Sbjct: 142 RELTEEDKKYIDES 155 >5XHW-A nrPDB Length = 237 Score = 34.7 bits (78), Expect = 0.14, Method: Composition-based stats. Identities = 28/121 (23%), Positives = 57/121 (47%), Gaps = 5/121 (4%) Query: 46 VLVADSFDRRFFPISKDQPRVLLPLANVALIDYTLEFLTATGVQETFVFCCWKAAQIKEH 105 V++A R +S D P+ ++ ++ + +E+L GVQ + +KA I + Sbjct: 17 VILAGGLGTRLKSVSGDIPKPMVDISGKPFLYRLMEYLEDQGVQRIILSLSYKADYIIDS 76 Query: 106 LLKSKWCRPTSLNVVRIITSELYRSLGDVLRDVDAKALVRSDFLLVYGDVISNINITRAL 165 L+K P + V II +E + G +++ K + S F+++ GD ++ + + Sbjct: 77 LIKDN---PVNSKVDFIIENEPLGT-GGAIKNA-CKYIEASKFIVINGDTYCELDYKKFI 131 Query: 166 E 166 E Sbjct: 132 E 132 >4D48-A nrPDB Length = 302 Score = 34.3 bits (77), Expect = 0.19, Method: Compositional matrix adjust. Identities = 17/63 (26%), Positives = 27/63 (42%) Query: 44 QAVLVADSFDRRFFPISKDQPRVLLPLANVALIDYTLEFLTATGVQETFVFCCWKAAQIK 103 +AV+ R P +K P+ +LPL + LI Y + A G+ E + I+ Sbjct: 10 KAVIPVAGLGTRMLPATKAIPKEMLPLVDKPLIQYVVNECIAAGINEIVLVTHSSKNSIE 69 Query: 104 EHL 106 H Sbjct: 70 NHF 72 >2UX8-A nrPDB Length = 297 Score = 34.3 bits (77), Expect = 0.21, Method: Compositional matrix adjust. Identities = 15/66 (22%), Positives = 30/66 (45%) Query: 41 PPLQAVLVADSFDRRFFPISKDQPRVLLPLANVALIDYTLEFLTATGVQETFVFCCWKAA 100 P +AV RF P +K P+ +LP+ + LI Y ++ G+++ + Sbjct: 13 PLRKAVFPVAGLGTRFLPATKAMPKEMLPVVDRPLIQYAVDEAVEAGIEQMIFVTGRGKS 72 Query: 101 QIKEHL 106 +++H Sbjct: 73 ALEDHF 78 >5MNI-E nrPDB Length = 431 Score = 33.9 bits (76), Expect = 0.22, Method: Compositional matrix adjust. Identities = 29/91 (31%), Positives = 43/91 (47%), Gaps = 11/91 (12%) Query: 369 GSNCFITNSVIGPGCHIGDNVVLDQTYLWQGVRVAAGAQIHQSLLCDNAEVKERVTLKPR 428 GS+ NS++ GC I +VV+ Q+ L+ VRV + I ++L V R Sbjct: 324 GSHGMTLNSLVSGGCVISGSVVV-QSVLFSRVRVNSFCNIDSAVLLPEVWVG-------R 375 Query: 429 SVLTSQVVVGPNITLPEGSVISLHPPDAEED 459 S + V+ +PEG VI +AEED Sbjct: 376 SCRLRRCVIDRACVIPEGMVIG---ENAEED 403 >2E3D-A nrPDB Length = 302 Score = 33.9 bits (76), Expect = 0.22, Method: Compositional matrix adjust. Identities = 17/63 (26%), Positives = 27/63 (42%) Query: 44 QAVLVADSFDRRFFPISKDQPRVLLPLANVALIDYTLEFLTATGVQETFVFCCWKAAQIK 103 +AV+ R P +K P+ +LPL + LI Y + A G+ E + I+ Sbjct: 10 KAVIPVAGLGTRMLPATKAIPKEMLPLVDKPLIQYVVNECIAAGITEIVLVTHSSKNSIE 69 Query: 104 EHL 106 H Sbjct: 70 NHF 72 >1YP3-A nrPDB Length = 451 Score = 33.9 bits (76), Expect = 0.27, Method: Compositional matrix adjust. Identities = 28/113 (24%), Positives = 51/113 (45%), Gaps = 23/113 (20%) Query: 324 EANFTDSTT-QSCTHSRHNIYR---GPEVSLGHGSILEENVLLGS--------------- 364 +A+ TDS + C I+ G + G+I+E+++L+G+ Sbjct: 325 DADVTDSVIGEGCVIKNCKIHHSVVGLRSCISEGAIIEDSLLMGADYYETDADRKLLAAK 384 Query: 365 GTV---IGSNCFITNSVIGPGCHIGDNV-VLDQTYLWQGVRVAAGAQIHQSLL 413 G+V IG NC I ++I IGDNV ++++ + + R G I ++ Sbjct: 385 GSVPIGIGKNCHIKRAIIDKNARIGDNVKIINKDNVQEAARETDGYFIKSGIV 437 Score = 30.8 bits (68), Expect = 2.3, Method: Compositional matrix adjust. Identities = 14/56 (25%), Positives = 30/56 (53%), Gaps = 1/56 (1%) Query: 55 RFFPISKDQPRVLLPL-ANVALIDYTLEFLTATGVQETFVFCCWKAAQIKEHLLKS 109 R +P++K + + +PL AN LID + + + + +V + +A + HL ++ Sbjct: 33 RLYPLTKKRAKPAVPLGANYRLIDIPVSNCLNSNISKIYVLTQFNSASLNRHLSRA 88 >3JUK-A nrPDB Length = 281 Score = 33.9 bits (76), Expect = 0.28, Method: Compositional matrix adjust. Identities = 14/46 (30%), Positives = 24/46 (52%) Query: 44 QAVLVADSFDRRFFPISKDQPRVLLPLANVALIDYTLEFLTATGVQ 89 + + A + RF PI+K P+ +LP+ + LI Y +E G + Sbjct: 4 KCLFPAAGYGTRFLPITKTIPKEMLPIVDKPLIQYAVEEAMEAGCE 49 >1HM0-A nrPDB Length = 468 Score = 33.5 bits (75), Expect = 0.32, Method: Compositional matrix adjust. Identities = 35/152 (23%), Positives = 59/152 (38%), Gaps = 38/152 (25%) Query: 299 RVSNLHMYSAVCADVIRRWVYPLTPEANFTDSTTQSCTHSRHNIYRGPEVSLGHGSILEE 358 R+++ HM + V + PEA + D + PEV + IL+ Sbjct: 251 RINHKHMVNGVSF---------VNPEATYIDIDVEIA----------PEVQIEANVILKG 291 Query: 359 NVLLGSGTVIGSNCFITNSVIGPGCHIGDNVVLDQTYLWQGVRVAAGAQIHQSLLCDNAE 418 +G+ TV+ + ++ +S IG G V + I +S + D Sbjct: 292 QTKIGAETVLTNGTYVVDSTIGAGA------------------VITNSMIEESSVADGVT 333 Query: 419 VKERVTLKPRSVLTSQVVVGPNITLPEGSVIS 450 V ++P S L +QV +G N +GS I Sbjct: 334 VGPYAHIRPNSSLGAQVHIG-NFVEVKGSSIG 364 >3FWW-A nrPDB Length = 456 Score = 33.5 bits (75), Expect = 0.38, Method: Compositional matrix adjust. Identities = 25/89 (28%), Positives = 40/89 (44%), Gaps = 1/89 (1%) Query: 339 RHNIYRGPEVSLGHGSILEENVLLGSGTVIGSNCFITNSVIGPGCHIGDNVVLDQTYLWQ 398 R + G ++++ I+E +V+LG IG+ C + N VIG I VL+ L Sbjct: 263 RGELTHGRDITIDTNVIIEGHVILGDRVRIGTGCVLKNCVIGDDSEISPYTVLEDARLDA 322 Query: 399 GVRVAAGAQIHQSL-LCDNAEVKERVTLK 426 V A++ L + A V V +K Sbjct: 323 NCTVGPFARLRPGAELAEGAHVGNFVEIK 351 >6F3A-U nrPDB Length = 190 Score = 32.7 bits (73), Expect = 0.53, Method: Composition-based stats. Identities = 22/77 (28%), Positives = 41/77 (53%), Gaps = 19/77 (24%) Query: 398 QGVRVAAGAQIHQSLLCDNAEVKERVTLKPRSVLTSQ---------VVVGP-NITLPEGS 447 + V++A GA ++C +E++ VT+ PR+V+ + +V+G N+ + Sbjct: 7 KSVKIAPGA-----VVCVESEIRGDVTIGPRTVIHPKARIIAEAGPIVIGEGNLIEEQAL 61 Query: 448 VISLHP----PDAEEDE 460 +I+ HP PDAE+ E Sbjct: 62 IINAHPDNITPDAEDSE 78 >1LVW-A nrPDB Length = 295 Score = 32.7 bits (73), Expect = 0.62, Method: Compositional matrix adjust. Identities = 14/65 (21%), Positives = 32/65 (49%) Query: 43 LQAVLVADSFDRRFFPISKDQPRVLLPLANVALIDYTLEFLTATGVQETFVFCCWKAAQI 102 ++ +++A R +PI++ + LLP+ + +I Y L L G+++ + + + Sbjct: 4 MKGIVLAGGSGTRLYPITRAVSKQLLPIYDKPMIYYPLSVLMLAGIRDILIISTPRDLPL 63 Query: 103 KEHLL 107 LL Sbjct: 64 YRDLL 68 >1MC3-A nrPDB Length = 296 Score = 32.0 bits (71), Expect = 0.93, Method: Compositional matrix adjust. Identities = 13/54 (24%), Positives = 27/54 (50%) Query: 43 LQAVLVADSFDRRFFPISKDQPRVLLPLANVALIDYTLEFLTATGVQETFVFCC 96 ++ +++A R PI++ + LLP+ + +I Y L L G++E + Sbjct: 4 MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITT 57 >3PMO-A nrPDB Length = 372 Score = 32.0 bits (71), Expect = 0.97, Method: Compositional matrix adjust. Identities = 17/47 (36%), Positives = 26/47 (55%), Gaps = 1/47 (2%) Query: 346 PEVSLGHGSILEENVLLGSGTVIGSNCFI-TNSVIGPGCHIGDNVVL 391 P S+G +++E +G+G IG++C I SVIG G + V L Sbjct: 136 PSASVGAYAVIESGARIGAGVSIGAHCVIGARSVIGEGGWLAPRVTL 182 >2V0L-A nrPDB Length = 456 Score = 31.2 bits (69), Expect = 1.6, Method: Compositional matrix adjust. Identities = 19/60 (31%), Positives = 29/60 (48%) Query: 339 RHNIYRGPEVSLGHGSILEENVLLGSGTVIGSNCFITNSVIGPGCHIGDNVVLDQTYLWQ 398 R + G +V + I+E NV LG IG+ C + N VIG I VL+ + + + Sbjct: 263 RGTLEHGKDVEIDVNVIIEGNVKLGDRVKIGTGCVLKNVVIGNDVEIKPYSVLEDSIVGE 322 >6FYY-m nrPDB Length = 405 Score = 30.8 bits (68), Expect = 2.1, Method: Compositional matrix adjust. Identities = 19/68 (27%), Positives = 36/68 (52%), Gaps = 3/68 (4%) Query: 646 LAAIEDFF-LEHEALGISMAKVLMAFYQLEILAEETILSWFSQRDTTDKGQQLRKN--QQ 702 + IE F LEH+ L + K+L+ Y +I++EE I+ + ++ +++ K + Sbjct: 325 MGGIERFLGLEHKDLIPLLPKILVQLYNNDIISEEEIMRFGTKSSKKFVPKEVSKKVRRA 384 Query: 703 LQRFIQWL 710 + FI WL Sbjct: 385 AKPFITWL 392 >5VI4-A nrPDB Length = 158 Score = 30.4 bits (67), Expect = 2.6, Method: Compositional matrix adjust. Identities = 16/39 (41%), Positives = 24/39 (61%), Gaps = 1/39 (2%) Query: 467 DDSGADQEKDKVKMKGY-NPAEVGAAGKGYLWKAAGMNM 504 DDSG DQE+D+V ++ Y +P+ +G G K +NM Sbjct: 37 DDSGKDQEQDQVLLRYYESPSPASQSGDGVDGKKLMVNM 75 >1OCX-A nrPDB Length = 182 Score = 30.4 bits (67), Expect = 3.2, Method: Compositional matrix adjust. Identities = 23/88 (26%), Positives = 40/88 (45%), Gaps = 15/88 (17%) Query: 368 IGSNCFITNSVIGPGCHIGDNVVLDQTYLWQGVRVAAGAQIHQSLLCDNAEVKERVTLKP 427 IG NC ++ PG HI T+ V +GA++ + + N V + Sbjct: 95 IGDNC-----MLAPGVHI-----YTATHPIDPVARNSGAELGKPVTIGN-----NVWIGG 139 Query: 428 RSVLTSQVVVGPNITLPEGSVISLHPPD 455 R+V+ V +G N+ + G+V++ PD Sbjct: 140 RAVINPGVTIGDNVVVASGAVVTKDVPD 167 >3Q1X-A nrPDB Length = 313 Score = 30.0 bits (66), Expect = 3.5, Method: Compositional matrix adjust. Identities = 13/34 (38%), Positives = 22/34 (64%) Query: 345 GPEVSLGHGSILEENVLLGSGTVIGSNCFITNSV 378 G V++G G+ + N+++GS IG+NC+I V Sbjct: 227 GDYVTIGTGAKVLGNIIVGSHVRIGANCWIDRDV 260 >1J2Z-A nrPDB Length = 270 Score = 30.0 bits (66), Expect = 3.9, Method: Compositional matrix adjust. Identities = 22/61 (36%), Positives = 31/61 (50%), Gaps = 2/61 (3%) Query: 350 LGHGSILEENVLLGSGTVIGSNCFITNSVIGPG-CHIGDNV-VLDQTYLWQGVRVAAGAQ 407 +G ++L V + VIGS+C + N V G IGD V + T + Q VR+A G Sbjct: 107 IGDKNLLMAYVHVAHDCVIGSHCILANGVTLAGHIEIGDYVNIGGLTAIHQFVRIAKGCM 166 Query: 408 I 408 I Sbjct: 167 I 167 >5VMK-A nrPDB Length = 462 Score = 29.6 bits (65), Expect = 5.4, Method: Compositional matrix adjust. Identities = 26/114 (22%), Positives = 46/114 (40%), Gaps = 22/114 (19%) Query: 339 RHNIYRGPEVSLGHGSILEENVLLGSGTVIGSNCFITNSVIGPGCHIGDNVVLDQTYLWQ 398 R + G +V + I+E N LG IG+ C + N+ I G + V D Sbjct: 268 RGTVKVGHDVRIDVNVIIEGNCELGDFVEIGAGCILKNTTIAAGTKVQAYSVFD------ 321 Query: 399 GVRVAAGAQIHQSLLCDNAEVKERVTLKPRSVLTSQVVVG-----PNITLPEGS 447 +++ +N ++ L+P + L ++V +G N T+ GS Sbjct: 322 -----------GAVVGENTQIGPFARLRPGAKLANEVHIGNFVEVKNTTIGLGS 364 >3CJ8-A nrPDB Length = 236 Score = 28.9 bits (63), Expect = 7.5, Method: Composition-based stats. Identities = 16/54 (29%), Positives = 27/54 (50%), Gaps = 1/54 (1%) Query: 339 RHNIYRGPEVSLGHGSILEENVLLGSGTVIGSNCFI-TNSVIGPGCHIGDNVVL 391 R + G + + G+IL ++G+GT+I + + +G CHIG VL Sbjct: 101 REKVEIGDQAVIMMGAILNIGAVVGAGTMIDMGAVLGGRATVGKHCHIGAGTVL 154 >3TIO-A nrPDB Length = 183 Score = 28.9 bits (63), Expect = 8.7, Method: Composition-based stats. Identities = 25/89 (28%), Positives = 41/89 (46%), Gaps = 12/89 (13%) Query: 326 NFTDSTTQSCTH-SRHN-----IYRGPEVSLGH-----GSILEENVLLGSGTVIGSNCFI 374 N D + TH S +N + G +V++GH G + VL+G G+++ + Sbjct: 58 NIQDGSMLHVTHKSSYNPDGNPLTIGEDVTVGHKVMLHGCTIGNRVLVGMGSILLDGAIV 117 Query: 375 TNSV-IGPGCHIGDNVVLDQTYLWQGVRV 402 + V IG G + N L+ YL+ G V Sbjct: 118 EDDVMIGAGSLVPQNKRLESGYLYLGSPV 146 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 6O85-A nrPDB 1067 0.0 6I7T-G nrPDB 848 0.0 6JLY-I nrPDB 845 0.0 5B04-E nrPDB 433 e-121 6EZO-E nrPDB 243 2e-64 4Y7U-A nrPDB 158 9e-39 Sequences not found previously or not previously below threshold: 6I7T-I nrPDB 87 2e-17 1YP3-A nrPDB 75 1e-13 3FWW-A nrPDB 71 1e-12 5Z09-A nrPDB 70 3e-12 2OI7-A nrPDB 69 8e-12 1LVW-A nrPDB 68 2e-11 2V0L-A nrPDB 67 4e-11 1HM0-A nrPDB 67 4e-11 1JYL-A nrPDB 66 4e-11 5XHW-A nrPDB 66 5e-11 1FWY-A nrPDB 63 7e-10 1WVC-A nrPDB 61 1e-09 5VE7-A nrPDB 59 5e-09 4HO3-A nrPDB 59 5e-09 5J49-A nrPDB 59 9e-09 2E3D-A nrPDB 58 1e-08 5I1F-A nrPDB 58 2e-08 5MNI-E nrPDB 56 6e-08 4D48-A nrPDB 56 7e-08 5VMK-A nrPDB 56 7e-08 6N0U-A nrPDB 56 8e-08 3PKP-A nrPDB 55 1e-07 6B5K-A nrPDB 54 1e-07 5IFY-A nrPDB 54 2e-07 1H5S-D nrPDB 54 2e-07 1MC3-A nrPDB 54 3e-07 4IHG-A nrPDB 53 5e-07 3TWD-A nrPDB 53 5e-07 5IDS-A nrPDB 52 8e-07 4G3P-A nrPDB 52 9e-07 2QKX-A nrPDB 52 1e-06 3ZLK-A nrPDB 51 1e-06 1XHD-A nrPDB 51 2e-06 4ECM-A nrPDB 50 3e-06 4E79-A nrPDB 50 4e-06 2UX8-A nrPDB 49 5e-06 3JUK-A nrPDB 49 8e-06 4MFG-A nrPDB 47 2e-05 1UG3-A nrPDB 46 4e-05 2PA4-A nrPDB 46 8e-05 4JD0-A nrPDB 45 1e-04 2MZB-A nrPDB 44 3e-04 6F1T-V nrPDB 44 3e-04 5NW4-h nrPDB 44 3e-04 3PMO-A nrPDB 42 6e-04 2WLD-A nrPDB 42 6e-04 3TIO-A nrPDB 42 7e-04 2X5Z-A nrPDB 42 9e-04 4R36-A nrPDB 41 0.003 2XWM-A nrPDB 41 0.003 1OCX-A nrPDB 40 0.003 4ISX-A nrPDB 39 0.005 5F42-A nrPDB 39 0.007 2CU2-A nrPDB 38 0.011 6FYY-m nrPDB 38 0.013 2IUA-A nrPDB 38 0.017 3R0S-A nrPDB 37 0.028 1KRR-A nrPDB 37 0.034 3R8Y-A nrPDB 36 0.046 3Q1X-A nrPDB 36 0.050 3T57-A nrPDB 36 0.069 5DEP-A nrPDB 36 0.073 2JF2-A nrPDB 36 0.074 1THJ-A nrPDB 35 0.093 3CJ8-A nrPDB 34 0.16 5AFU-U nrPDB 34 0.18 1H7T-A nrPDB 34 0.20 4EQY-A nrPDB 34 0.21 1J2Z-A nrPDB 34 0.23 3MQG-A nrPDB 34 0.25 4CVH-A nrPDB 34 0.27 2NPO-A nrPDB 34 0.31 5JXX-A nrPDB 33 0.42 3IGJ-A nrPDB 33 0.46 6F3A-U nrPDB 33 0.48 4HSO-A nrPDB 33 0.55 3F1C-A nrPDB 32 0.64 5JBE-A nrPDB 32 1.1 2P2O-A nrPDB 31 1.5 5TXC-A nrPDB 31 1.6 3LKD-A nrPDB 31 2.3 4E6U-A nrPDB 31 2.7 3SGI-A nrPDB 30 3.4 1ZAU-A nrPDB 30 4.1 3G0S-A nrPDB 30 4.6 6NVA-A nrPDB 29 5.5 2YFN-A nrPDB 29 7.0 6G5I-z nrPDB 29 9.5 >6O85-A nrPDB Length = 721 Score = 1067 bits (2759), Expect = 0.0, Method: Composition-based stats. Identities = 721/721 (100%), Positives = 721/721 (100%) Query: 1 MAAPVVAPPGVVVSRANKRSGAGPGGSGGGGARGAEEEPPPPLQAVLVADSFDRRFFPIS 60 MAAPVVAPPGVVVSRANKRSGAGPGGSGGGGARGAEEEPPPPLQAVLVADSFDRRFFPIS Sbjct: 1 MAAPVVAPPGVVVSRANKRSGAGPGGSGGGGARGAEEEPPPPLQAVLVADSFDRRFFPIS 60 Query: 61 KDQPRVLLPLANVALIDYTLEFLTATGVQETFVFCCWKAAQIKEHLLKSKWCRPTSLNVV 120 KDQPRVLLPLANVALIDYTLEFLTATGVQETFVFCCWKAAQIKEHLLKSKWCRPTSLNVV Sbjct: 61 KDQPRVLLPLANVALIDYTLEFLTATGVQETFVFCCWKAAQIKEHLLKSKWCRPTSLNVV 120 Query: 121 RIITSELYRSLGDVLRDVDAKALVRSDFLLVYGDVISNINITRALEEHRLRRKLEKNVSV 180 RIITSELYRSLGDVLRDVDAKALVRSDFLLVYGDVISNINITRALEEHRLRRKLEKNVSV Sbjct: 121 RIITSELYRSLGDVLRDVDAKALVRSDFLLVYGDVISNINITRALEEHRLRRKLEKNVSV 180 Query: 181 MTMIFKESSPSHPTRCHEDNVVVAVDSTTNRVLHFQKTQGLRRFAFPLSLFQGSSDGVEV 240 MTMIFKESSPSHPTRCHEDNVVVAVDSTTNRVLHFQKTQGLRRFAFPLSLFQGSSDGVEV Sbjct: 181 MTMIFKESSPSHPTRCHEDNVVVAVDSTTNRVLHFQKTQGLRRFAFPLSLFQGSSDGVEV 240 Query: 241 RYDLLDCHISICSPQVAQLFTDNFDYQTRDDFVRGLLVNEEILGNQIHMHVTAKEYGARV 300 RYDLLDCHISICSPQVAQLFTDNFDYQTRDDFVRGLLVNEEILGNQIHMHVTAKEYGARV Sbjct: 241 RYDLLDCHISICSPQVAQLFTDNFDYQTRDDFVRGLLVNEEILGNQIHMHVTAKEYGARV 300 Query: 301 SNLHMYSAVCADVIRRWVYPLTPEANFTDSTTQSCTHSRHNIYRGPEVSLGHGSILEENV 360 SNLHMYSAVCADVIRRWVYPLTPEANFTDSTTQSCTHSRHNIYRGPEVSLGHGSILEENV Sbjct: 301 SNLHMYSAVCADVIRRWVYPLTPEANFTDSTTQSCTHSRHNIYRGPEVSLGHGSILEENV 360 Query: 361 LLGSGTVIGSNCFITNSVIGPGCHIGDNVVLDQTYLWQGVRVAAGAQIHQSLLCDNAEVK 420 LLGSGTVIGSNCFITNSVIGPGCHIGDNVVLDQTYLWQGVRVAAGAQIHQSLLCDNAEVK Sbjct: 361 LLGSGTVIGSNCFITNSVIGPGCHIGDNVVLDQTYLWQGVRVAAGAQIHQSLLCDNAEVK 420 Query: 421 ERVTLKPRSVLTSQVVVGPNITLPEGSVISLHPPDAEEDEDDGEFSDDSGADQEKDKVKM 480 ERVTLKPRSVLTSQVVVGPNITLPEGSVISLHPPDAEEDEDDGEFSDDSGADQEKDKVKM Sbjct: 421 ERVTLKPRSVLTSQVVVGPNITLPEGSVISLHPPDAEEDEDDGEFSDDSGADQEKDKVKM 480 Query: 481 KGYNPAEVGAAGKGYLWKAAGMNMEEEEELQQNLWGLKINMEEESESESEQSMDSEEPDS 540 KGYNPAEVGAAGKGYLWKAAGMNMEEEEELQQNLWGLKINMEEESESESEQSMDSEEPDS Sbjct: 481 KGYNPAEVGAAGKGYLWKAAGMNMEEEEELQQNLWGLKINMEEESESESEQSMDSEEPDS 540 Query: 541 RGGSPQMDDIKVFQNEVLGTLQRGKEENISCDNLVLEINSLKYAYNISLKEVMQVLSHVV 600 RGGSPQMDDIKVFQNEVLGTLQRGKEENISCDNLVLEINSLKYAYNISLKEVMQVLSHVV Sbjct: 541 RGGSPQMDDIKVFQNEVLGTLQRGKEENISCDNLVLEINSLKYAYNISLKEVMQVLSHVV 600 Query: 601 LEFPLQQMDSPLDSSRYCALLLPLLKAWSPVFRNYIKRAADHLEALAAIEDFFLEHEALG 660 LEFPLQQMDSPLDSSRYCALLLPLLKAWSPVFRNYIKRAADHLEALAAIEDFFLEHEALG Sbjct: 601 LEFPLQQMDSPLDSSRYCALLLPLLKAWSPVFRNYIKRAADHLEALAAIEDFFLEHEALG 660 Query: 661 ISMAKVLMAFYQLEILAEETILSWFSQRDTTDKGQQLRKNQQLQRFIQWLKEAEEESSED 720 ISMAKVLMAFYQLEILAEETILSWFSQRDTTDKGQQLRKNQQLQRFIQWLKEAEEESSED Sbjct: 661 ISMAKVLMAFYQLEILAEETILSWFSQRDTTDKGQQLRKNQQLQRFIQWLKEAEEESSED 720 Query: 721 D 721 D Sbjct: 721 D 721 >6I7T-G nrPDB Length = 712 Score = 848 bits (2190), Expect = 0.0, Method: Composition-based stats. Identities = 206/726 (28%), Positives = 358/726 (49%), Gaps = 52/726 (7%) Query: 15 RANKRSGAGPGGSGGGGARGAEEEPPPPLQAVLVADSFDRRFFPISKDQPRVLLPLANVA 74 + K+SG G G + ++ + LQAV++ DS++ RF P++ +PR LLPLANV Sbjct: 5 KGQKKSGLGNHG------KNSDMDVEDRLQAVVLTDSYETRFMPLTAVKPRCLLPLANVP 58 Query: 75 LIDYTLEFLTATGVQETFVFCCWKAAQIKEHLLKSKWCRPTSLNVVRIITSELYRSLGDV 134 LI+YTLEFL GV E F+ C A QI +++ SKW P S + I S R GDV Sbjct: 59 LIEYTLEFLAKAGVHEVFLICSSHANQINDYIENSKWNLPWSPFKITTIMSPEARCTGDV 118 Query: 135 LRDVDAKALVRSDFLLVYGDVISNINITRALEEHRLRRKLEKNVSVMTMIFKESSPSHPT 194 +RD+D + ++ DF+LV GDV++NI+ ++ LE H+ + L+ + TM ++S T Sbjct: 119 MRDLDNRGIITGDFILVSGDVLTNIDFSKMLEFHK-KMHLQDKDHISTMCLSKASTYPKT 177 Query: 195 RCHEDNVVVAVDSTTNRVLHFQK----TQGLRRFAFPLSLFQGSSDGVEVRYDLLDCHIS 250 R E V +D +T+R +++Q + + + D +R DL+DC I Sbjct: 178 RTIEPAAFV-LDKSTSRCIYYQDLPLPSSREKTSIQIDPELLDNVDEFVIRNDLIDCRID 236 Query: 251 ICSPQVAQLFTDNFDYQT-RDDFVRGLLVNEEILGNQIHMHVTAKEYGARVSNLHMYSAV 309 IC+ V +F +NFDYQ+ R DFV+G +++ +ILG I+ ++T EY RV + Y + Sbjct: 237 ICTSHVPLIFQENFDYQSLRTDFVKG-VISSDILGKHIYAYLT-DEYAVRVESWQTYDTI 294 Query: 310 CADVIRRWVYPLTPEANFTDSTTQSCTHSRHNIYRGPEVSLGHGSILEENVLLGSGTVIG 369 D + RW YPL ++N D T S SRH IY+ +V L + + +GSGT IG Sbjct: 295 SQDFLGRWCYPLVLDSNIQDDQTYS-YESRH-IYKEKDVVLAQSCKIGKCTAIGSGTKIG 352 Query: 370 SNCFITNSVIGPGCHIGDNVVLDQTYLWQGVRVAAGAQIHQSLLCDNAEVKERVTLKPRS 429 I NSVIG C IG+N+ + +++W + + I SL+ NA + V L Sbjct: 353 EGTKIENSVIGRNCQIGENIRIKNSFIWDDCIIGNNSIIDHSLIASNATLGSNVRLNDGC 412 Query: 430 VLTSQVVVGPNITLPEGSVISLHP-PDAEEDEDDGEFSDDSGADQEKDKVKMKGYNPAEV 488 ++ V + N+ L + IS P +A D E ++ D + + + + V Sbjct: 413 IIGFNVKIDDNMDLDRNTKISASPLKNAGSRMYDNESNEQFDQDLDDQTLAV-----SIV 467 Query: 489 GAAGKGYLWKAAGMNMEEEE-ELQQNLWGLKINMEEESESESEQSMDSEEPDSRGGSPQM 547 G G GY++++ + E+ E + + L ++E S+ S +++ R + + Sbjct: 468 GDKGVGYIYESEVSDDEDSSTEACKEINTLSNQLDELYLSDDSISSATKKTKKR-RTMSV 526 Query: 548 DDIKVFQNEV-------------LGTLQRGKEENISCDNLVLEINSLKYAYNISLKEVM- 593 + I + E+ + T++R E N D +LE+N+L+ + N++ EV Sbjct: 527 NSIYTDREEIDSEFEDEDFEKEGIATVERAMENNHDLDTALLELNTLRMSMNVTYHEVRI 586 Query: 594 ---QVLSHVVLEFPLQQMDSPLDSSRYCALLLPLLKAWSPVFRNYIKRAADHLEALAAIE 650 L V F Q P D+ ++ + W +F+ ++++ + I Sbjct: 587 ATITALLRRVYHFIATQTLGPKDA------VVKVFNQWGLLFKRQAFDEEEYIDLMNIIM 640 Query: 651 DFFLEH--EALGISMAKVLMAFYQLEILAEETILSWFSQRDTTDKGQQLRKNQQLQRFIQ 708 + +E + + + L++ Y +I+ E+ I W+ T + +++K ++++ Sbjct: 641 EKIVEQSFDKPDLILFSALVSLYDNDIIEEDVIYKWWDNVSTDPRYDEVKK--LTVKWVE 698 Query: 709 WLKEAE 714 WL+ A+ Sbjct: 699 WLQNAD 704 >6JLY-I nrPDB Length = 678 Score = 845 bits (2182), Expect = 0.0, Method: Composition-based stats. Identities = 232/693 (33%), Positives = 371/693 (53%), Gaps = 41/693 (5%) Query: 31 GARGAEEEPPPPLQAVLVADSFDRRFFPISKDQPRVLLPLANVALIDYTLEFLTATGVQE 90 G G E+P LQA++++DS++ RF P++ D+PR LLPLAN LI+YT EFL GVQE Sbjct: 6 GLNGKLEKPKHALQAIVLSDSYNYRFRPLTLDKPRCLLPLANTPLIEYTFEFLALAGVQE 65 Query: 91 TFVFCCWKAAQIKEHLLKSKWCRPTSLNVVRIITSELYRSLGDVLRDVDAKALVRSDFLL 150 +VFCC A QI+E++ KSKW P+S V I S S+GD LR++D+K L+ SDF+L Sbjct: 66 VYVFCCAHAGQIREYIEKSKWNLPSSPFSVNTIVSRESLSVGDALRELDSKQLITSDFIL 125 Query: 151 VYGDVISNINITRALEEHRLRRKLEKNVSVMTMIFKESSPSHPTRCHEDNVVVAVDSTTN 210 V GDV+SN+ + L+EHR RR+ +KN ++MTM+ +E+SP H TR ++ V +D T+ Sbjct: 126 VSGDVVSNVPLNEVLKEHRKRREDDKN-AIMTMVVREASPFHRTRARTESSVFVIDKKTS 184 Query: 211 RVLHFQKTQGLRRFAFPLSLFQGSSDGVEVRYDLLDCHISICSPQVAQLFTDNFDYQ-TR 269 + +H+Q + + + + +EVR DL+DC I ICS V LFT+NFDYQ R Sbjct: 185 QCVHYQANERGKHYVSMDPEIFNEHEELEVRNDLIDCQIDICSNDVPALFTENFDYQDIR 244 Query: 270 DDFVRGLLVNEEILGNQIHMHVTAKEYGARVSNLHMYSAVCADVIRRWVYPLTPEANFTD 329 DFV G+L + ++LG +IH HV + Y ARV +L Y A+ DV+ RWVYP P++N + Sbjct: 245 KDFVYGVLTS-DLLGKKIHCHVAKENYAARVRSLQTYDAISKDVLSRWVYPFVPDSNLLN 303 Query: 330 STTQSCTHSRHNIYRGPEVSLGHGSILEENVLLGSGTVIGSNCFITNSVIGPGCHIGDNV 389 Q+ ++ RH IY+ +V L I++ L+G+ T +G + N++IG C IG N Sbjct: 304 ---QTFSYQRHQIYKEEDVVLARSCIIKARTLIGAYTKVGDASVVANTIIGRNCTIGSNC 360 Query: 390 VLDQTYLWQGVRVAAGAQIHQSLLCDNAEVKERVTLKPRSVLTSQVVVGPNITLPEGSVI 449 +D +LW+ V + +I +++L ++ ++ +++ +++ + VV+G N + + + Sbjct: 361 SIDSAFLWEDVVIGDNCRIGKAILANSVKIGNNCSIEDGAIVAAGVVIGDNTIIEKNKRL 420 Query: 450 SLHPPDAEEDEDDGEFSDDSGADQEKDKVKMKGYNPAEVGAAGKGYLWKAAGMNMEEEEE 509 + ++ +D G QE AE + +G +A+G+ +E E Sbjct: 421 TTFESHSQGTLNDPSLVGIGGRGQEYH---------AEEDSDDEGEFMEASGL-IESTNE 470 Query: 510 LQQNLWGLKINMEEESESESEQSMD----SEEPDSRGGSPQMD-DIKVFQNEVLGTLQRG 564 L L + E+ S SE+ M+ S DS D D F E +L+R Sbjct: 471 LH-----LSDSESSETSSSSEEDMEFIPFSARRDSANTINSEDFDEGDFNKEAQQSLERA 525 Query: 565 KEENISCDNLVLEINSLKYAYNISLKEVMQVLSHVVLEFPLQQMDSPLDSSRYCALLLPL 624 EEN D LE+N+L+ A N + EV + +L + SP ++ L + Sbjct: 526 FEENHQIDIAALELNTLRMAMNANYHEVRSAIVLALLRRIMHLDVSPKEA------LAKV 579 Query: 625 LKAWSPVFRNYIKRAADHLEALAAIEDFFLEHEALGISMAK----VLMAFYQLEILAEET 680 + W P+ K H E + + L+ + +SM + +L FYQLEI E Sbjct: 580 MTRWGPLL---AKLTFSHEEQVDNV--LTLQKYCVRLSMTRHFLQLLGYFYQLEIAEENA 634 Query: 681 ILSWFSQRDTTDKGQQLRKNQQLQRFIQWLKEA 713 I W+S +++ ++ ++F+ WL A Sbjct: 635 IQEWYSDPRSSEGELAALRDAGGKQFVDWLNTA 667 >5B04-E nrPDB Length = 458 Score = 433 bits (1112), Expect = e-121, Method: Composition-based stats. Identities = 95/461 (20%), Positives = 178/461 (38%), Gaps = 76/461 (16%) Query: 2 AAPVVAPPGVVVSRANKRSGAGPGGSGGGGARG--AEEEPPPPLQAVLVADSFDRRFFPI 59 A P+ + P ++ G GG RG + P QAV+ A F +P+ Sbjct: 8 ALPLASSPSIL------------GPISGGRNRGNIQLQSIPIEFQAVVFA-GFGNSLYPL 54 Query: 60 SKDQ--PRVLLPLANVALIDYTLEFLTATGVQETFVFCCWKAAQIKEHLLKSKWCRPTSL 117 + P+ LLP+ N ++ Y L +L A G + C +A L+S + + Sbjct: 55 TGSDALPKALLPIGNKPMLHYPLYWLEAAGFTSAILICMEEAEAHINAWLRSGYEGHMRI 114 Query: 118 NVVRIITSELYRSLGDVLRDVDAKALVRSDFLLVYGDVISNINITRALEEHRLRRKLEKN 177 +V + +S D LR V L+++DF+ + D I + L++ RL Sbjct: 115 HVEAPTILDDSKSSADALRAV--SHLIKNDFVCLSCDSIVGLPPYTVLDKFRLDNP--SA 170 Query: 178 VSVMTMIFKESSPSHPTRCHEDNVVVAVDSTTNRVLHFQKTQG-LRRFAFPLSLFQGSSD 236 ++V + + K + ++ + ++ ++ T+R+L+ + + F F +SL Sbjct: 171 LAVYSPVLKYEHITSQSKEIDAKQLIGIEEKTSRLLYAKSSADVGSDFTFRMSLLWKHPR 230 Query: 237 GVEVRYDLLDCHISICSPQVAQLFT----------DNFDYQTRDDFVRGLLVNEEI---- 282 V + +L D HI + V L D Y + + + V E I Sbjct: 231 -VTLNTNLSDAHIFVFKHWVIDLIREKESISSIRGDLIPYLVKCQYQKSFTVRENIQRFL 289 Query: 283 ------------LGNQ-IHMHVTAKEY---GARVSNLHMYSAVCADVIRRWVYPLTPEAN 326 L +Q I ++ + +R +NL Y + + + LTPE Sbjct: 290 SSPNNIDNYDGGLSSQEIKINALIAKDGIICSRANNLPNYFE-----LNKCIAKLTPEQR 344 Query: 327 FTDSTTQSCTHSRHNIYRGPEVSLGHGSILEENVLLGSGTVIGSNCFITNSVIGPGCHIG 386 D V++ +++ + ++ GT I N I S+IG C IG Sbjct: 345 LVD------------------VTVSERALVGADCMVNEGTTIKDNSNIKKSIIGKNCVIG 386 Query: 387 DNVVLDQTYLWQGVRVAAGAQIHQSLLCDNAEVKERVTLKP 427 VV+ + L + V G ++ ++ A++ + L+ Sbjct: 387 KGVVVSNSILMDNIVVEDGVRLESCIVASGAQIGAKSKLRE 427 >6EZO-E nrPDB Length = 452 Score = 243 bits (620), Expect = 2e-64, Method: Composition-based stats. Identities = 89/463 (19%), Positives = 157/463 (33%), Gaps = 99/463 (21%) Query: 42 PLQAVLVADSFDRRFFPISKDQPRVLLPLANVALIDYTLEFLTATGVQETFVFCCWKAAQ 101 QAV++A R ++ P+ LLP+ N LI Y L L G +E V + Sbjct: 2 EFQAVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTTRDVQK 61 Query: 102 IKEHLLKSKWCRPTSLNVVRIITSELYRSLGDVLRDVDAKALVRSDFLLVYGDVISNINI 161 L +++ ++V I D LR + K ++D L++ D+I+++ + Sbjct: 62 A----LCAEFKMKMKPDIVCIPDDADM-GTADSLRYIYPKL--KTDVLVLSCDLITDVAL 114 Query: 162 TRALEEHRLRRKLEKNVSVMTMIFKESS----PSH----PTRCHEDNVVVAVDSTTNRVL 213 ++ R + + M+ ++ P + E + VDST R+L Sbjct: 115 HEVVDLFR------AYDASLAMLMRKGQDSIEPVPGQKGKKKAVEQRDFIGVDSTGKRLL 168 Query: 214 HFQKTQGL-RRFAFPLSLFQGSSDGVEVRYDLLDCHISICSPQVAQLFTDN--------- 263 L S+ Q + L+D H+ + +N Sbjct: 169 FMANEADLDEELVIKGSILQKHPR-IRFHTGLVDAHLYCLKKYIVDFLMENGSITSIRSE 227 Query: 264 -FDYQTRDDF-------------------------VRGLLVNEEILG------------- 284 Y R F + + L Sbjct: 228 LIPYLVRKQFSSASSQQGQEEKEEDLKKKELKSLDIYSFIKEANTLNLAPYDACWNACRG 287 Query: 285 ----------NQIHMHVTAKEYGARVSNLHMYSAVCADVIRRWVYPLTPEANFTDSTTQS 334 + ++H+ + +RVS L +Y V + + L PE S+ Q Sbjct: 288 DRWEDLSRSQVRCYVHIMKEGLCSRVSTLGLYMEANRQV-PKLLSALCPEEPPVHSSAQ- 345 Query: 335 CTHSRHNIYRGPEVSLGHGSILEENVLLGSGTVIGSNCFITNSVIGPGCHIGDNVVLDQT 394 S+H ++ + L+G T IG I SVIG C I D V + Sbjct: 346 -IVSKH--------------LVGVDSLIGPETQIGEKSSIKRSVIGSSCLIKDRVTITNC 390 Query: 395 YLWQGVRVAAGAQIHQSLLCDNAEVKERVTLKPRSVLTSQVVV 437 L V V G+ I S++C+NA +++ +K ++ S + Sbjct: 391 LLMNSVTVEEGSNIQGSVICNNAVIEKGADIKD-CLIGSGQRI 432 >4Y7U-A nrPDB Length = 231 Score = 158 bits (398), Expect = 9e-39, Method: Composition-based stats. Identities = 34/122 (27%), Positives = 58/122 (47%), Gaps = 5/122 (4%) Query: 43 LQAVLVADSFDRRFFPISKDQPRVLLPLANVALIDYTLEFLTATGVQETFVFCCWKAAQI 102 ++A+++A R P++ P+ L+P+A LI+Y L L A GV E + W QI Sbjct: 1 MKAMILAAGKGERMRPLTLHTPKPLVPVAGQPLIEYHLRALAAAGVTEVVINHAWLGQQI 60 Query: 103 KEHLLKSKWCRPTSLNVVRIITSELYRSLGDVLRDVDAKALVRSDFLLVYGDVISNINIT 162 ++HL L++ E + G + + + L + FLLV GDV ++ + Sbjct: 61 EDHLGDGS---RFGLSIRYSPEGEPLETGGGIFKAL--PLLGDAPFLLVNGDVWTDYDFA 115 Query: 163 RA 164 R Sbjct: 116 RL 117 >6I7T-I nrPDB Length = 578 Score = 87.2 bits (214), Expect = 2e-17, Method: Composition-based stats. Identities = 83/539 (15%), Positives = 175/539 (32%), Gaps = 108/539 (20%) Query: 54 RRFFPISKDQPRVLLPLANVALIDYTLEFLTATGVQETFV----------------FCCW 97 F S P+ LLP+ N +I+Y L++ +E V F Sbjct: 55 NEFMQHSTRLPKALLPIGNRPMIEYVLDWCDQADFKEISVVAPVDEIELIESGLTSFLSL 114 Query: 98 KAAQ---IKEHLLKSKWCRPTS-LNVVRIITSELYRSLGDVLRDVDAKALVRSDFLLVYG 153 + Q I + L S + I S+ + + +++ + + DF+++ Sbjct: 115 RKQQFELIYKALSNSNHSHHLQDPKKINFIPSKANSTGESLQKELLPR--INGDFVILPC 172 Query: 154 DVISNINITRALEEHRLRRKLEKNVSVMTMIFKES------------------SPSHPTR 195 D +++I +++ R R + N MT+ +K S + Sbjct: 173 DFVTDIPPQVLVDQFRNR---DDNNLAMTIYYKNSLDSSIDKKQQQKQKQQQFFTVYSEN 229 Query: 196 CHEDNVVVAVDSTTNRVLHFQKTQGLRRFAFPLSLFQGSSDGVEVRYDLLDCHISICSPQ 255 + + +D + R + L + + V LL+ I CS + Sbjct: 230 EDSERQPILLDVYSQR-----DVTKTKYLQIRSHLLWNYPN-LTVSTKLLNSFIYFCSFE 283 Query: 256 VAQLFTDNFDYQTRD-DFVRGLLVNEE------ILGNQIHMHVTAKEYGARVSNL-HMYS 307 + QL +R F N++ ++ H +Y +++ Y Sbjct: 284 LCQLLKLGPQSMSRQASFKDPFTGNQQQQNPPTTDDDEDRNHDDDDDYKPSATSIQPTYF 343 Query: 308 AVCADVI------RRWVYPLTPEANFTDSTTQSCTHSRHNIYRGPEVSLGHGSILEENVL 361 D+I + + + F D + +S HS+ G + + N L Sbjct: 344 KKKNDLILDPINCNKSLSKV-----FRDLSRRSWQHSKPREPIGIFILPNETLFIRANNL 398 Query: 362 -----------------------------LGSGTVIGSNC------FITNSVIGPGCHIG 386 +G+ ++ C + SV+G +IG Sbjct: 399 NAYMDANRFVLKIKSQTMFTKNIQIQSAAIGADAIVDPKCQISAHSNVKMSVLGTQANIG 458 Query: 387 DNVVLDQTYLWQGVRVAAGAQIHQSLLCDNAEVKERVTLKPRSVLTSQVVVGPNITLPEG 446 + + L+ GV + + ++ A++ + L + VV P Sbjct: 459 SRCRVAGSLLFPGVHLGDEVILENCIIGPMAKIGSKCKLSN-CYIEGHYVVEPKNNFKGE 517 Query: 447 SVISLHPPDAEEDE---DDGEFSDDSGADQEKDKVKMKGYNPAEVGAAGKGYLWKAAGM 502 ++ +++ + EEDE DD + +S +E D + + + Y ++ G+ Sbjct: 518 TLANVYLDEDEEDELIYDDSVIAGESEIAEETDSDDRSDEDSDDSEYTDE-YEYEDDGL 575 >1YP3-A nrPDB Length = 451 Score = 74.8 bits (182), Expect = 1e-13, Method: Composition-based stats. Identities = 75/435 (17%), Positives = 162/435 (37%), Gaps = 50/435 (11%) Query: 54 RRFFPISKDQPRVLLPL-ANVALIDYTLEFLTATGVQETFVFCCWKAAQIKEHLLK---- 108 R +P++K + + +PL AN LID + + + + +V + +A + HL + Sbjct: 32 TRLYPLTKKRAKPAVPLGANYRLIDIPVSNCLNSNISKIYVLTQFNSASLNRHLSRAYAS 91 Query: 109 --SKWCRPTSLNVVRIITSEL----YRSLGDVLRD---VDAKALVRSDFLLVYGDVISNI 159 + + V+ S ++ D +R + + V ++L++ GD + + Sbjct: 92 NMGGYKNEGFVEVLAAQQSPENPDWFQGTADAVRQYLWLFEEHTVL-EYLILAGDHLYRM 150 Query: 160 NITRALEEHRLRRKLEKNVSVMTMIFKESSPSHPTRCHEDNVVVAVDSTTNRVLHFQKTQ 219 + + ++ HR + V+ + M K ++ + E+ ++ ++ Q Sbjct: 151 DYEKFIQAHR-ETDADITVAALPMDEKRATAFGLMKIDEEGRIIEFAEKPQ----GEQLQ 205 Query: 220 GLRRFAFPLSLFQGSSDGVEVRYDLLDCHISICSPQVAQ-LFTDNFDYQTRDDFVRGLLV 278 ++ L L + + + I + S V L D F +DF ++ Sbjct: 206 AMKVDTTILGLDDKRAKEMPF---IASMGIYVISKDVMLNLLRDKFP--GANDFGSEVIP 260 Query: 279 NEEILGNQIHMHVTAKEYGARVSNLHMYSAVCADVIRRWVYPLTPEANFTDSTTQSCTHS 338 LG ++ ++ Y + + + + ++ V P+ +F D + T Sbjct: 261 GATSLGMRVQAYL-YDGYWEDIGTIEAFYNANLGITKKPV----PDFSFYDRSAPIYTQP 315 Query: 339 RHNIYRGPEVSLGHGSILEENVLLGSGTVIGSNCFITNSVIGPGCHIGDNVVLDQTYLWQ 398 R Y P L + ++G G VI NC I +SV+G I + +++ + L Sbjct: 316 R---YLPPSKMLDADV---TDSVIGEGCVIK-NCKIHHSVVGLRSCISEGAIIEDSLLMG 368 Query: 399 GVRVAAGAQIHQSLLCDNAE----VKERVTLKPRSVLTSQVVVGPNITLPEGSVISLHPP 454 A + LL + + +K R+++ +G N+ +I+ Sbjct: 369 ADYYETDA--DRKLLAAKGSVPIGIGKNCHIK-RAIIDKNARIGDNV-----KIINKDNV 420 Query: 455 DAEEDEDDGEFSDDS 469 E DG F Sbjct: 421 QEAARETDGYFIKSG 435 >3FWW-A nrPDB Length = 456 Score = 71.4 bits (173), Expect = 1e-12, Method: Composition-based stats. Identities = 70/387 (18%), Positives = 134/387 (34%), Gaps = 44/387 (11%) Query: 43 LQAVLVADSFDRRFFPISKDQPRVLLPLANVALIDYTLEFLTATGVQETFVFCCWKAAQI 102 + V++A R + D P+VL PLA ++ + ++ G Q + + Sbjct: 6 MSVVILAAGKGTRMY---SDLPKVLHPLAGKPMVQHVIDAAMKLGAQHVHLVYGHGGELL 62 Query: 103 KEHLLKSKWCRPTSLNVVRIITSELYRSLGDVLRDVDAKALVRSDFLLVYGDV-ISNINI 161 K+ L + G ++ D L++YGDV + +++ Sbjct: 63 KKTLADPSLNW---------VLQAEQLGTGHAMQQAAPHFADDEDILMLYGDVPLISVDT 113 Query: 162 TRALEEHRLRRKLEKNVSVMTMIFKESSPSHPTRCHEDNVVVAVDSTTNRVLHFQKTQGL 221 + L L K E + ++T+ S E+ VV + + + Sbjct: 114 LQRL----LAAKPEGGIGLLTVKLDNPSGYGRI-VRENGDVVGI-------VEHKDASDA 161 Query: 222 RRFAFPLSLFQGSSDGVEVRYDLLDCHISICSPQVAQLFTDNFDYQTRDDFVRGLLVNEE 281 +R + E+ +L + ++ L +N + ++ ++ Sbjct: 162 QR------------EINEINTGILVANGRDLKRWLSLLDNNNAQGEF---YITDIIALAH 206 Query: 282 ILGNQI-HMHVTAKEYGARVSNLHMYSAVCADVIRRWVYPLTPEANFTDSTTQSCTHSRH 340 G +I +H T V+N SA+ L S R Sbjct: 207 ADGKKIATVHPTRLSEVEGVNNRLQLSALERVFQTEQAEKLLLAGVMLLDP--SRFDLRG 264 Query: 341 NIYRGPEVSLGHGSILEENVLLGSGTVIGSNCFITNSVIGPGCHIGDNVVLDQTYLWQGV 400 + G ++++ I+E +V+LG IG+ C + N VIG I VL+ L Sbjct: 265 ELTHGRDITIDTNVIIEGHVILGDRVRIGTGCVLKNCVIGDDSEISPYTVLEDARLDANC 324 Query: 401 RVAAGAQIH-QSLLCDNAEVKERVTLK 426 V A++ + L + A V V +K Sbjct: 325 TVGPFARLRPGAELAEGAHVGNFVEIK 351 >5Z09-A nrPDB Length = 409 Score = 69.8 bits (169), Expect = 3e-12, Method: Composition-based stats. Identities = 69/446 (15%), Positives = 151/446 (33%), Gaps = 102/446 (22%) Query: 43 LQAVLVADSFDRRFFPISKDQPRVLLPLANVALIDYTLEFLTATGVQETFVFCCWKAAQI 102 ++A ++A R PI+ +P+ +P+ + LI+Y +E+L G+++ V K + Sbjct: 1 MKAFILAAGSGERLEPITHTRPKAFVPILSKPLIEYQIEYLRKCGIRDITVIVSSKNKEY 60 Query: 103 KEHLLKSKWCRPTSLNVVRIITSELYRSLGDVLRDV---DAKALVRSDFLLVYGDVISNI 159 E LK + + + + G + D ++ D I NI Sbjct: 61 FEKKLKE---------ISIVTQKDDIKGTGAAILSAKFNDEALIINGDLFFSNEKEICNI 111 Query: 160 NITRALEEHRLRRKLEKNVSVMTMIFKESSPSH-PTRCHEDNVVVAVDSTTNRVLHFQKT 218 + KE++ +D V+ +D+ N Sbjct: 112 -----------------------ITLKENAIIGVKVSNPKDYGVLVLDNQNN-------- 140 Query: 219 QGLRRFAFPLSLFQGSSDGVEVRYDLLDCHISICSPQVAQLFTDNFDYQTRDDF-VRGLL 277 LS + +L++ I +L +D F Y + RG L Sbjct: 141 ---------LSKIIEKPE--IPPSNLINAGIY-------KLNSDIFTYLDKISISERGEL 182 Query: 278 VNEEILGNQIHMHVTAKEYGARVSNLHMY-SAVCADV----IRRW-VYPLTPEANFTDST 331 + +++ AK++ +V Y + + +W + L N + Sbjct: 183 ELTDA------INLMAKDHRVKVIEYEGYWMDIGKPWNIIDVNKWALDNLVFSQNLGNVE 236 Query: 332 TQSCTHSRHNIYRGPEVSLGHGSILEENVLLGSGTVIGSNCFITN-SVIGPGCHIGDNVV 390 + I + + G+ +E V +G G+ IG N ++ +++ IG +V Sbjct: 237 DNVKIKGKVII--EEDAEIKSGTYIEGPVYIGKGSEIGPNSYLRPYTILVEKNKIGASVE 294 Query: 391 LDQTYLWQGVRVAAGAQIHQSLLCDNAEVKERVTL------------------------K 426 + ++ + +G ++ + + S++ ++ + K Sbjct: 295 VKESVIMEGSKIPHLSYVGDSVIAEDVNFGAGTLIANLRFDEKEVKVNVKGKRISSGRRK 354 Query: 427 PRSVLTSQVVVGPNITLPEGSVISLH 452 + + V G N+T+ G I + Sbjct: 355 LGAFIGGHVRTGINVTILPGVKIGAY 380 >2OI7-A nrPDB Length = 456 Score = 68.7 bits (166), Expect = 8e-12, Method: Composition-based stats. Identities = 77/421 (18%), Positives = 137/421 (32%), Gaps = 56/421 (13%) Query: 42 PLQAVLVADSFDRRFFPISKDQPRVLLPLANVALIDYTLEFLTATGVQETFVFCCWKAAQ 101 + V++A R + D P+VL LA A++ + ++ G + Sbjct: 5 AMSVVILAAGKGTRMY---SDLPKVLHTLAGKAMVQHVIDAANELGAAHVHLVYGHGGDL 61 Query: 102 IKEHLLKSKWCRPTSLNVVRIITSELYRSLGDVLRDVDAKALVRSDFLLVYGDVISNINI 161 +K+ L L ++ T + D D L++YGDV + Sbjct: 62 LKQALKDD--NLNWVLQAEQLGTGHAMQQAAPFFAD-------DEDILMLYGDV----PL 108 Query: 162 TRALEEHRLRR-KLEKNVSVMTMIFKESSPSHPTRCHEDNVVVAVDSTTNRVLHFQKTQG 220 RLR K + + ++T+ + + E+ V + H T Sbjct: 109 ISVETLQRLRDAKPQGGIGLLTVKLDDPTGYGRI-TRENGKVTGIVE------HKDATDE 161 Query: 221 LRRFAFPLSLFQGSSDGVEVRYDLLDCHISICSPQVAQLFTDNF--DYQTRDDFVRGLLV 278 R+ E+ +L + + +A+L +N +Y D Sbjct: 162 QRQIQ-------------EINTGILIANGADMKRWLAKLTNNNAQGEYYITDIIALAYQE 208 Query: 279 NEEILGNQIHMHVTAKEYGARVSNLHMYSAVCADVIRRWVYPLTPEANFTDSTTQSCTHS 338 EI+ +H V+N S + L + Sbjct: 209 GREIVA----VHPQRLSEVEGVNNRLQLSRLERVYQSEQAEKLLLAGVMLRDPAR--FDL 262 Query: 339 RHNIYRGPEVSLGHGSILEENVLLGSGTVIGSNCFITNSVIGPGCHIGDNVVLDQTYLWQ 398 R + G +V + I+E NV LG IG+ C I NSVIG C I V++ L Sbjct: 263 RGTLTHGRDVEIDTNVIIEGNVTLGHRVKIGTGCVIKNSVIGDDCEISPYTVVEDANLAA 322 Query: 399 GVRVAAGAQIH-QSLLCDNAEVKE-----RVTLKPRSVLT-----SQVVVGPNITLPEGS 447 + A++ + L + A V + L S +G N+ + G+ Sbjct: 323 ACTIGPFARLRPGAELLEGAHVGNFVEMKKARLGKGSKAGHLTYLGDAEIGDNVNIGAGT 382 Query: 448 V 448 + Sbjct: 383 I 383 >1LVW-A nrPDB Length = 295 Score = 67.9 bits (164), Expect = 2e-11, Method: Composition-based stats. Identities = 30/171 (17%), Positives = 64/171 (37%), Gaps = 10/171 (5%) Query: 43 LQAVLVADSFDRRFFPISKDQPRVLLPLANVALIDYTLEFLTATGVQETFVFCCWKAAQI 102 ++ +++A R +PI++ + LLP+ + +I Y L L G+++ + + + Sbjct: 4 MKGIVLAGGSGTRLYPITRAVSKQLLPIYDKPMIYYPLSVLMLAGIRDILIISTPRDLPL 63 Query: 103 -KEHLLKSKWCRPTSLNVVRIITSELYRSLGDVLRDVDAKALVRSDFLLVYGD-VISNIN 160 ++ L + + E R + D V + S LV GD V Sbjct: 64 YRDLLGDGS---QFGVRFSYRVQEEP-RGIADAF-IVGKDFIGDSKVALVLGDNVFYGHR 118 Query: 161 ITRALEEHRLRRKLEKNVSVMTMIFKESSPSHPTRCHEDNVVVAVDSTTNR 211 + L R LE + ++ P + V++++ +R Sbjct: 119 FSEIL---RRAASLEDGAVIFGYYVRDPRPFGVVEFDSEGRVISIEEKPSR 166 >2V0L-A nrPDB Length = 456 Score = 66.8 bits (161), Expect = 4e-11, Method: Composition-based stats. Identities = 64/414 (15%), Positives = 138/414 (33%), Gaps = 66/414 (15%) Query: 40 PPPLQAVLVADSFDRRFFPISKDQPRVLLPLANVALIDYTLEFLTATGVQETFVFCCWKA 99 L AV++A R + D P+VL +A ++ + ++ G + + Sbjct: 3 KKALSAVILAAGKGTRMY---SDLPKVLHTIAGKPMVKHVIDTAHQLGSENIHLIYGHGG 59 Query: 100 AQIKEHLLKSKWCRPTSLNVVRIITSELYRSLGDVLRDVDAKALVRSDFLLVYGDVISNI 159 ++ HL + L ++ T+ + +D + ++ D L+ + + + Sbjct: 60 DLMRTHLANEQVN--WVLQTEQLGTAHAVQQAAPFFKDNENIVVLYGDAPLITKETLEKL 117 Query: 160 NITRALEEHRLRRKLEKNVSVMTMIFKESSPSHPTRCHEDNVVVAVDSTTNRVLHFQKTQ 219 + K E ++++T+ + NVV V+ QK Sbjct: 118 ----------IEAKPENGIALLTVNLDNPTGYGRIIRENGNVVAIVE---------QKDA 158 Query: 220 GLRRFAFPLSLFQGSSDGVEVRYDLLDCHISICSPQVAQLFTDNFDYQTRDDFVRGLLVN 279 + EV ++ + +A++ +N + ++ L+ Sbjct: 159 NAEQLNIK-----------EVNTGVMVSDGASFKKWLARVGNNN----AQGEYYLTDLIA 203 Query: 280 EEILGNQ--IHMHVTAKEYGARVSNLHM---YSAVCADVIRRWVYPLTPEANFTDSTTQS 334 L NQ + V + +A+ + L E + Sbjct: 204 ---LANQDNCQVVAVQATDVMEVEGANNRLQLAALERYFQNKQASKLLLEGVMIYDPAR- 259 Query: 335 CTHSRHNIYRGPEVSLGHGSILEENVLLGSGTVIGSNCFITNSVIGPGCHIGDNVVLDQT 394 R + G +V + I+E NV LG IG+ C + N VIG Sbjct: 260 -FDLRGTLEHGKDVEIDVNVIIEGNVKLGDRVKIGTGCVLKNVVIG-------------- 304 Query: 395 YLWQGVRVAAGAQIHQSLLCDNAEVKERVTLKPRSVLTSQVVVGPNITLPEGSV 448 V + + + S++ + A + L+P + L ++ VG + + + +V Sbjct: 305 ---NDVEIKPYSVLEDSIVGEKAAIGPFSRLRPGAELAAETHVGNFVEIKKSTV 355 >1HM0-A nrPDB Length = 468 Score = 66.8 bits (161), Expect = 4e-11, Method: Composition-based stats. Identities = 65/413 (15%), Positives = 128/413 (30%), Gaps = 66/413 (15%) Query: 33 RGAEEEPPPPLQAVLVADSFDRRFFPISKDQPRVLLPLANVALIDYTLEFLTATGVQETF 92 RG+ A+++A R D P+VL +A ++++++ + A ++T Sbjct: 2 RGSHHHHHHSNFAIILAAGKGTRMK---SDLPKVLHKVAGISMLEHVFRSVGAIQPEKTV 58 Query: 93 VFCCWKAAQIKEHLLKSKWCRPTSLNVVRIITSELYRSLGDVLRDVDAKALVRSDFLLVY 152 KA ++E L + SE + V+ + L++ Sbjct: 59 TVVGHKAELVEEVLAGQ---------TEFVTQSEQLGTGHAVMMTEPILEGLSGHTLVIA 109 Query: 153 GDV--ISNINITRALEEHRLRRKLEKNVSVMTMIFKESSPSHPTRCH---EDNVVVAVDS 207 GD I+ ++ ++ H + + + +P R V+ V+ Sbjct: 110 GDTPLITGESLKNLIDFH-----INHKNVATILTAETDNPFGYGRIVRNDNAEVLRIVEQ 164 Query: 208 TTNRVLHFQ-KTQGLRRFAFPLSLFQGSSDGVEVRYDLLDCHISICSPQVAQLFTDNFDY 266 Q K + F + + + +I V +F + Sbjct: 165 KDATDFEKQIKEINTGTYVFDNERLFEALKNINTNNAQGEYYI----TDVIGIFRET--- 217 Query: 267 QTRDDFVRGLLVNEEILGNQIHMHVTAKEYGARVSNLHMYSAVCADVIRRWVYPLTPEAN 326 G ++ + + N + A V+RR + N Sbjct: 218 -----------------GEKVGAYTLKDFDESLGVNDRVALATAESVMRRRI-------N 253 Query: 327 FTDSTTQSCTHSRHNIYRGPEVSLGHGSILEENVLLGSGTVIGSNCFITNSVIGPGCHIG 386 + Y +V + +E NV+L T IG+ +TN IG Sbjct: 254 HKHMVNGVSFVNPEATYIDIDVEIAPEVQIEANVILKGQTKIGAETVLTNGTYVVDSTIG 313 Query: 387 DNVVLDQTYLWQGVRVAAGAQIHQSLLCDNAEVKERVTLKPRSVLTSQVVVGP 439 V+ + I +S + D V ++P S L +QV +G Sbjct: 314 AGAVITNSM------------IEESSVADGVTVGPYAHIRPNSSLGAQVHIGN 354 >1JYL-A nrPDB Length = 254 Score = 66.4 bits (160), Expect = 4e-11, Method: Composition-based stats. Identities = 25/115 (21%), Positives = 52/115 (45%), Gaps = 4/115 (3%) Query: 33 RGAEEEPPPPLQAVLVADSFDRRFFPISKDQPRVLLPLANVALIDYTLEFLTATGVQETF 92 RG+ + ++A+++A R P++++ P+ L+ + LI+Y +EFL G+ + Sbjct: 17 RGSHMK-EIRVKAIILAAGLGTRLRPLTENTPKALVQVNQKPLIEYQIEFLKEKGINDII 75 Query: 93 VFCCWKAAQIKEHLLKSKWCRPTSLNVVRIITSELYRSLGDVLRDVDAKALVRSD 147 + + Q LK K+ N + Y SL V ++ ++ +D Sbjct: 76 IIVGYLKEQFD--YLKEKYGVRLVFNDKYADYNNFY-SLYLVKEELANSYVIDAD 127 >5XHW-A nrPDB Length = 237 Score = 66.4 bits (160), Expect = 5e-11, Method: Composition-based stats. Identities = 28/121 (23%), Positives = 55/121 (45%), Gaps = 5/121 (4%) Query: 46 VLVADSFDRRFFPISKDQPRVLLPLANVALIDYTLEFLTATGVQETFVFCCWKAAQIKEH 105 V++A R +S D P+ ++ ++ + +E+L GVQ + +KA I + Sbjct: 17 VILAGGLGTRLKSVSGDIPKPMVDISGKPFLYRLMEYLEDQGVQRIILSLSYKADYIIDS 76 Query: 106 LLKSKWCRPTSLNVVRIITSELYRSLGDVLRDVDAKALVRSDFLLVYGDVISNINITRAL 165 L+K P + V II +E + G + K + S F+++ GD ++ + + Sbjct: 77 LIK---DNPVNSKVDFIIENEPLGTGGAIKNA--CKYIEASKFIVINGDTYCELDYKKFI 131 Query: 166 E 166 E Sbjct: 132 E 132 >1FWY-A nrPDB Length = 331 Score = 62.5 bits (150), Expect = 7e-10, Method: Composition-based stats. Identities = 69/369 (18%), Positives = 120/369 (32%), Gaps = 45/369 (12%) Query: 42 PLQAVLVADSFDRRFFPISKDQPRVLLPLANVALIDYTLEFLTATGVQETFVFCCWKAAQ 101 + V++A R + D P+VL LA A++ + ++ G + Sbjct: 5 AMSVVILAAGKGTRMY---SDLPKVLHTLAGKAMVQHVIDAANELGAAHVHLVYGHGGDL 61 Query: 102 IKEHLLKSKWCRPTSLNVVRIITSELYRSLGDVLRDVDAKALVRSDFLLVYGDVISNINI 161 +K+ L L ++ T + D D L++YGDV + Sbjct: 62 LKQALKDD--NLNWVLQAEQLGTGHAMQQAAPFFAD-------DEDILMLYGDV----PL 108 Query: 162 TRALEEHRLRR-KLEKNVSVMTMIFKESSPSHPTRCHEDNVVVAVDSTTNRVLHFQKTQG 220 RLR K + + ++T+ + + E+ V + H T Sbjct: 109 ISVETLQRLRDAKPQGGIGLLTVKLDDPTGYGRI-TRENGKVTGIVE------HKDATDE 161 Query: 221 LRRFAFPLSLFQGSSDGVEVRYDLLDCHISICSPQVAQLFTDNF--DYQTRDDFVRGLLV 278 R+ E+ +L + + +A+L +N +Y D Sbjct: 162 QRQIQ-------------EINTGILIANGADMKRWLAKLTNNNAQGEYYITDIIALAYQE 208 Query: 279 NEEILGNQIHMHVTAKEYGARVSNLHMYSAVCADVIRRWVYPLTPEANFTDSTTQSCTHS 338 EI+ +H V+N S + L + Sbjct: 209 GREIVA----VHPQRLSEVEGVNNRLQLSRLERVYQSEQAEKLLLAGVMLRDPAR--FDL 262 Query: 339 RHNIYRGPEVSLGHGSILEENVLLGSGTVIGSNCFITNSVIGPGCHIGDNVVLDQTYLWQ 398 R + G +V + I+E NV LG IG+ C I NSVIG C I V++ L Sbjct: 263 RGTLTHGRDVEIDTNVIIEGNVTLGHRVKIGTGCVIKNSVIGDDCEISPYTVVEDANLAA 322 Query: 399 GVRVAAGAQ 407 + A+ Sbjct: 323 ACTIGPFAR 331 >1WVC-A nrPDB Length = 259 Score = 61.4 bits (147), Expect = 1e-09, Method: Composition-based stats. Identities = 23/145 (15%), Positives = 57/145 (39%), Gaps = 21/145 (14%) Query: 44 QAVLVADSFDRRFFPISKDQPRVLLPLANVALIDYTLEFLTATGVQETFVFCCWKAAQIK 103 +AV++A R + +P+ ++ + ++ + ++ + G+++ + C +K IK Sbjct: 4 KAVILAGGLGTRLSEETIVKPKPMVEIGGKPILWHIMKMYSVHGIKDFIICCGYKGYVIK 63 Query: 104 EHLLKSKWCRPTS-------------------LNVVRIITSELYRSLGDVLRDVDAKALV 144 E+ + S V ++ + G L+ V Sbjct: 64 EYFAN--YFLHMSDVTFHMAENRMEVHHKRVEPWNVTLVDTGDSSMTGGRLKRVAEYVKD 121 Query: 145 RSDFLLVYGDVISNINITRALEEHR 169 FL YGD +++++I ++ H+ Sbjct: 122 DEAFLFTYGDGVADLDIKATIDFHK 146 >5VE7-A nrPDB Length = 302 Score = 59.4 bits (142), Expect = 5e-09, Method: Composition-based stats. Identities = 37/169 (21%), Positives = 61/169 (36%), Gaps = 17/169 (10%) Query: 44 QAVLVADSFDRRFFPISKDQPRVLLPLANVALIDYTLEFLTATGVQETFVFCCWKAAQIK 103 +AV RF P +K P+ +LP+ + LI Y +E A G+ E I+ Sbjct: 14 KAVFPVAGLGTRFLPATKASPKEMLPVVDKPLIQYAVEEAIAAGITEMIFVTGRSKRAIE 73 Query: 104 EHLLKSKWCRPTSLNVV-RIITSELYRSLG----DVLRDVDAKALVRSDFLLVYGDVISN 158 +H KS + L + EL RS+ D +AL +L ++++ Sbjct: 74 DHFDKS-YEVEAELEARGKAKLLELVRSIKPSHVDCFYVRQPEALGLGHAVLCAEKLVAD 132 Query: 159 INITRALEEHRLRRKLEKNVSVMTMIFKESSPSHPTRCHEDNVVVAVDS 207 L L+ N VM + H + V+ V+ Sbjct: 133 NPFAVIL----ADDLLDGNPPVMKQMVDVFDHYH-------SSVIGVEE 170 >4HO3-A nrPDB Length = 297 Score = 59.4 bits (142), Expect = 5e-09, Method: Composition-based stats. Identities = 26/167 (15%), Positives = 64/167 (38%), Gaps = 8/167 (4%) Query: 43 LQAVLVADSFDRRFFPISKDQPRVLLPLANVALIDYTLEFLTATGVQETFVFCCWKAAQI 102 ++ ++++ R +P++K + LLP+ + ++ Y L L G+++ + + Sbjct: 1 MKGIILSGGSGTRLYPLTKVVSKQLLPVYDKPMVYYPLSVLMLAGIKDILIISTPEDTPR 60 Query: 103 KEHLLKSKWCRPTSLNVVRIITSELYRSLGDVLRDVDAKALVRSDFLLVYGD-VISNINI 161 E LL SL+ + +S + + + + + + LV GD + Sbjct: 61 FEQLLGGGSELGISLSY-AVQSSPDGLAQAFI---IGEEFIGDDNVALVLGDNIFYGHGF 116 Query: 162 TRALEEHRLRRKLEKNVSVMTMIFKESSPSHPTRCHEDNVVVAVDST 208 T L+ R+ ++ K+ E V++++ Sbjct: 117 TELLQRAANRK---SGATIFGYNVKDPQRFGVVEFDEKGKVISIEEK 160 >5J49-A nrPDB Length = 301 Score = 58.7 bits (140), Expect = 9e-09, Method: Composition-based stats. Identities = 20/66 (30%), Positives = 30/66 (45%) Query: 44 QAVLVADSFDRRFFPISKDQPRVLLPLANVALIDYTLEFLTATGVQETFVFCCWKAAQIK 103 +AV RF P +K P+ +LP+ + LI Y +E A G+ E I+ Sbjct: 14 KAVFPVAGLGTRFLPATKASPKEMLPIVDKPLIQYAVEEAMAAGITEMIFVTGRSKRAIE 73 Query: 104 EHLLKS 109 +H KS Sbjct: 74 DHFDKS 79 >2E3D-A nrPDB Length = 302 Score = 57.9 bits (138), Expect = 1e-08, Method: Composition-based stats. Identities = 48/294 (16%), Positives = 87/294 (29%), Gaps = 39/294 (13%) Query: 44 QAVLVADSFDRRFFPISKDQPRVLLPLANVALIDYTLEFLTATGVQETFVFCCWKAAQIK 103 +AV+ R P +K P+ +LPL + LI Y + A G+ E + I+ Sbjct: 10 KAVIPVAGLGTRMLPATKAIPKEMLPLVDKPLIQYVVNECIAAGITEIVLVTHSSKNSIE 69 Query: 104 EHLLKSKWCRPTSLNVVRIITSELYRSLGDVLRDVDAKAL-----------VRSDFLLVY 152 H TS + ++ + R L D ++ + + +L Sbjct: 70 NHFD-------TSFELEAMLEKRVKRQLLDEVQSICPPHVTIMQVRQGLAKGLGHAVLCA 122 Query: 153 GDVISNINITRALEEHRLR--RKLEKNVSVMTMIFKESSPSHPTRCHEDNVVVAVDSTTN 210 V+ + + L + L ++ MI + H E D T Sbjct: 123 HPVVGDEPVAVILPDVILDEYESDLSQDNLAEMIRRFDETGHSQIMVEPVA----DVTAY 178 Query: 211 RVLHFQKTQGLRRFAFPLSLFQGSSDGVEVRYDLLDCHISICSPQV-AQL---------- 259 V+ + + + P+ +L + S + L Sbjct: 179 GVVDCKGVELAPGESVPMVGVVEKPKADVAPSNLAIVGRYVLSADIWPLLAKTPPGAGDE 238 Query: 260 --FTDNFDYQTRDDFVRGLLV--NEEILGNQIHMHVTAKEYGARVSNLHMYSAV 309 TD D + V + GN++ EYG R + L Sbjct: 239 IQLTDAIDMLIEKETVEAYHMKGKSHDCGNKLGYMQAFVEYGIRHNTLGTEFKA 292 >5I1F-A nrPDB Length = 302 Score = 57.5 bits (137), Expect = 2e-08, Method: Composition-based stats. Identities = 41/255 (16%), Positives = 81/255 (31%), Gaps = 24/255 (9%) Query: 44 QAVLVADSFDRRFFPISKDQPRVLLPLANVALIDYTLEFLTATGVQETFVFCCWKAAQIK 103 +AV RF P +K P+ +LP+ + LI Y +E G+ E I+ Sbjct: 14 KAVFPVAGLGTRFLPATKASPKEMLPVVDKPLIQYAVEEAIEAGITEMIFVTGRSKRAIE 73 Query: 104 EHLLKSKWCRPTSLNVVR-----IITSELYRSLGDVLRDVDAKALVRSDFLLVYGDVISN 158 +H KS + L + + S D A+AL +L ++ + Sbjct: 74 DHFDKS-YEIEAELEARGKEKLLSLVRSIKPSHVDCFYVRQAEALGLGHAVLCAEKLVGD 132 Query: 159 INITRALEEHRLRRKLEKNVSVMTMIFKESSPSHPTRCHEDNVVVAVDS---TTNRVLHF 215 L + L T + ++ H V+ V+ ++ Sbjct: 133 NPFAVILADDLLDGP--------TPVLRQ---MIDVFDHYHASVIGVEEIAPADSKSYGV 181 Query: 216 QKTQGLRRFAFPLSLFQGSSDGVEVRYDLLDCHISICSPQVAQLFTDNFD----YQTRDD 271 + F LS + + + + P++ + D Sbjct: 182 IDGKRWEDDLFKLSGIVEKPEPAQAPSNFGVVGRYVLKPKIFKHLRGLKPGAGGELQLTD 241 Query: 272 FVRGLLVNEEILGNQ 286 ++ LL +E++L + Sbjct: 242 AIQSLLTDEQVLAYR 256 >5MNI-E nrPDB Length = 431 Score = 56.0 bits (133), Expect = 6e-08, Method: Composition-based stats. Identities = 68/425 (16%), Positives = 144/425 (33%), Gaps = 62/425 (14%) Query: 38 EPPPPLQAVLVADSFDRRFFPISKDQPRVLLPLANV-ALIDYTLEFLTATGVQETFVFCC 96 + P A+++A R ++ + + + +ID+ L +G++ V Sbjct: 15 QLPLKSVALILAGGRGTRLKDLTNKRAKPAVHFGGKFRIIDFALSNCINSGIRRMGVITQ 74 Query: 97 WKAAQIKEHLLK--SKWCRPTSLNVVRIITSEL------YRSLGDVL-RDVDAKALVRSD 147 +++ + +H+ + S + + V + + YR D + +++D +++ Sbjct: 75 YQSHTLVQHIQRGWSFFNEEMNEFVDLLPAQQRMKGENWYRGTADAVTQNLDIIRAYKAE 134 Query: 148 FL-LVYGDVISNINITRALEEHRLRRKLEKNVSVMTMIFKESSPSHPTRCHEDNVVVAVD 206 ++ ++ GD I + +R L +H + + V+ M + +E+S V+AVD Sbjct: 135 YVVILAGDHIYKQDYSRMLIDH-VEKGARCTVACMPVPIEEASAF---------GVMAVD 184 Query: 207 STTNRVLHFQKTQGLRRFAFPLSLFQGSSDGVEVRYDLLDCHISICSPQVA--QLFTDNF 264 + +K S L I + L D+ Sbjct: 185 ENDKIIEFVEKPANPPSMPNDPSK------------SLASMGIYVFDADYLYELLEEDDR 232 Query: 265 DYQTRDDFVRGLL--VNEEILG-------NQIHMHVTAKEYGARVSNLHMYSAVCADVIR 315 D + DF + L+ + E L + + A+ Y V L Y D Sbjct: 233 DENSSHDFGKDLIPKITEAGLAYAHPFPLSCVQSDPDAEPYWRDVGTLEAYWKANLD--- 289 Query: 316 RWVYPLTPEANFTDSTTQSCTHSRHNIYRGPEVSLGHGSILEENVLLGSGTVIGSNCFIT 375 + + PE + D T++ + N L+ G VI S + Sbjct: 290 --LASVVPELDMYDRNWPIRTYNESLPPAKFVQDRSGSHGMTLNSLVSGGCVI-SGSVVV 346 Query: 376 NSVIGPGCHIGDNVVLDQTYLWQGVRVAAGAQIHQSLLCDNAEVKERVTLKPRSVLTSQV 435 SV+ + +D L V V ++ + ++ V+ + Sbjct: 347 QSVLFSRVRVNSFCNIDSAVLLPEVWVGRSCRLRRCVI------------DRACVIPEGM 394 Query: 436 VVGPN 440 V+G N Sbjct: 395 VIGEN 399 >4D48-A nrPDB Length = 302 Score = 55.6 bits (132), Expect = 7e-08, Method: Composition-based stats. Identities = 18/66 (27%), Positives = 28/66 (42%) Query: 44 QAVLVADSFDRRFFPISKDQPRVLLPLANVALIDYTLEFLTATGVQETFVFCCWKAAQIK 103 +AV+ R P +K P+ +LPL + LI Y + A G+ E + I+ Sbjct: 10 KAVIPVAGLGTRMLPATKAIPKEMLPLVDKPLIQYVVNECIAAGINEIVLVTHSSKNSIE 69 Query: 104 EHLLKS 109 H S Sbjct: 70 NHFDTS 75 >5VMK-A nrPDB Length = 462 Score = 55.6 bits (132), Expect = 7e-08, Method: Composition-based stats. Identities = 57/427 (13%), Positives = 134/427 (31%), Gaps = 56/427 (13%) Query: 46 VLVADSFDRRFFPISKDQPRVLLPLANVALIDYTLEFLTATGVQETFVFCCWKAAQIKEH 105 +++A R P+VL PLA L+ + ++ + E + +H Sbjct: 14 IILAAGKGTRMR---SQLPKVLQPLAGRPLLGHVIK-TAKQLLAENIITIYGHGG---DH 66 Query: 106 LLKSKWCRPTSLNVVRIITSELYRSLGDVLRDVDAKALVRSDFLLVYGDVISNINITRAL 165 + K+ + ++ + G ++ L++YGDV + R Sbjct: 67 VKKT-----FAQENIQWVEQAEQLGTGHAVQMTLPVLPKDGISLILYGDV----PLVRQT 117 Query: 166 EEHRLRRKLEKNVSVMTMIFKESSPSHPTRCHEDNVVVAVDSTTNRVLHFQKTQGLRRFA 225 +L ++ + + +P+ R +V D ++ + +R Sbjct: 118 TLEQL-IEVSNKTGIGMITLHVDNPTGYGR------IVRQDGKIQAIVEHKDATEAQR-- 168 Query: 226 FPLSLFQGSSDGVEVRYDLLDCHISICSPQVAQLFTDNFDYQTRDDFVRGLLVNEEILGN 285 E+ + + + +L +N +G +I+ Sbjct: 169 ----------QIQEINTGIYCVSNAKLHEWLPKLSNEN---------AQGEYYLTDIV-- 207 Query: 286 QIHMHVTAKEYGARVSNLHMYSAVCADVIRRWVYPLTPEANFTDSTTQSCTHSRHNIYRG 345 A G ++++ A + + + E F + Sbjct: 208 -----AMAVADGLEIASIQPELAFEVEGVNDRLQLAALEREFQKQQAKELMQQGVTFADP 262 Query: 346 PEVSLGHGSILEENVLLGSGTVIGSNCFITNSVIGPGCHIGDNVVLDQTYLWQGVRVAAG 405 L + +V + +I NC +G IG +L T + G +V A Sbjct: 263 ARFDLRGTVKVGHDVRIDVNVIIEGNCE-----LGDFVEIGAGCILKNTTIAAGTKVQAY 317 Query: 406 AQIHQSLLCDNAEVKERVTLKPRSVLTSQVVVGPNITLPEGSVISLHPPDAEEDEDDGEF 465 + +++ +N ++ L+P + L ++V +G + + ++ + D E Sbjct: 318 SVFDGAVVGENTQIGPFARLRPGAKLANEVHIGNFVEVKNTTIGLGSKANHFTYLGDAEI 377 Query: 466 SDDSGAD 472 +S Sbjct: 378 GAESNIG 384 >6N0U-A nrPDB Length = 305 Score = 55.6 bits (132), Expect = 8e-08, Method: Composition-based stats. Identities = 22/130 (16%), Positives = 51/130 (39%), Gaps = 7/130 (5%) Query: 44 QAVLVADSFDRRFFPISKDQPRVLLPLANVALIDYTLEFLTATGVQETFVFCCWKAAQIK 103 + +++A R +PI+ + LLP+ + +I Y L L G+++ + + Sbjct: 12 KGIILAGGSGTRLYPITHVVSKQLLPVYDKPMIYYPLSTLMVAGIRDVLIISTPQDTPRF 71 Query: 104 EHLLKSKWCRPTSLNVVRIIT-SELYRSLGDVLRDVDAKALVRSDFLLVYGD-VISNINI 161 E +L +N+ + S + + + + + L+ GD + ++ Sbjct: 72 EAMLGDG--SQWGMNIQYAVQPSPDGLAQAFI---IGREFVGNDPSALILGDNIFYGHDL 126 Query: 162 TRALEEHRLR 171 + LE R Sbjct: 127 AKQLERANAR 136 >3PKP-A nrPDB Length = 292 Score = 54.8 bits (130), Expect = 1e-07, Method: Composition-based stats. Identities = 22/125 (17%), Positives = 49/125 (39%), Gaps = 7/125 (5%) Query: 44 QAVLVADSFDRRFFPISKDQPRVLLPLANVALIDYTLEFLTATGVQETFVFCC-WKAAQI 102 + +++A R +P++ + LLP+ + +I Y L L G+++ + + Sbjct: 5 KGIILAGGSGTRLYPVTMAVSKQLLPIYDKPMIYYPLSTLMLAGIRDILIISTPQDTPRF 64 Query: 103 KEHLLKSKWCRPTSLNVVRIITSELYRSLGDVLRDVDAKALVRSDFLLVYGD-VISNINI 161 ++ L LN+ S L + + + D LV GD + ++ Sbjct: 65 QQLLGDGS---QWGLNLQYK-VSPSPDGLAQAF-IIGEEFIGHDDCALVLGDNIFYGHDL 119 Query: 162 TRALE 166 + +E Sbjct: 120 PKLME 124 >6B5K-A nrPDB Length = 296 Score = 54.4 bits (129), Expect = 1e-07, Method: Composition-based stats. Identities = 23/114 (20%), Positives = 43/114 (37%), Gaps = 4/114 (3%) Query: 43 LQAVLVADSFDRRFFPISKDQPRVLLPLANVALIDYTLEFLTATGVQETFVFCCWKAAQI 102 ++ +++A R +PI+ + LLP+ + +I Y L L G+++ + A Sbjct: 1 MRGIILAGGSGTRLYPITMGISKQLLPVYDKPMIYYPLTTLMMAGIRDIQLITTPHDAPG 60 Query: 103 KEHLLKSKWCRPTSLNVVRIITSELYRSLGDVLRDVDAKALVRSDFLLVYGDVI 156 LL +N+ + L + A + LV GD I Sbjct: 61 FHRLLGDG--AHLGVNISYATQDQP-DGLAQAF-VIGANHIGADSVALVLGDNI 110 >5IFY-A nrPDB Length = 305 Score = 54.4 bits (129), Expect = 2e-07, Method: Composition-based stats. Identities = 20/126 (15%), Positives = 45/126 (35%), Gaps = 7/126 (5%) Query: 44 QAVLVADSFDRRFFPISKDQPRVLLPLANVALIDYTLEFLTATGVQETFVFCC-WKAAQI 102 + +++A R +PI+ + LLP+ + +I Y L L G+++ + + Sbjct: 12 KGIILAGGSGTRLYPITHAVSKQLLPVYDKPMIYYPLSTLMIAGIRDVLIISTPQDTPRF 71 Query: 103 KEHLLKSKWCRPTSLNVVRIITSELYRSLGDVLRDVDAKALVRSDFLLVYGD-VISNINI 161 + L +N+ L + + L+ GD + ++ Sbjct: 72 ESMLGDGS---QWGMNIQYATQPSP-DGLAQAF-VIGRDFVGNEPSALILGDNIFYGHDL 126 Query: 162 TRALEE 167 + LE Sbjct: 127 AKQLER 132 >1H5S-D nrPDB Length = 293 Score = 54.0 bits (128), Expect = 2e-07, Method: Composition-based stats. Identities = 21/126 (16%), Positives = 51/126 (40%), Gaps = 9/126 (7%) Query: 44 QAVLVADSFDRRFFPISKDQPRVLLPLANVALIDYTLEFLTATGVQETFVFCC-WKAAQI 102 + +++A R +P++ + LLP+ + +I Y L L G+++ + + Sbjct: 5 KGIILAGGSGTRLYPVTMAVSKQLLPIYDKPMIYYPLSTLMLAGIRDILIISTPQDTPRF 64 Query: 103 KEHLLKSKWCRPTSLNVVRIIT-SELYRSLGDVLRDVDAKALVRSDFLLVYGD-VISNIN 160 ++ L LN+ + S + + + + + D LV GD + + Sbjct: 65 QQLLGDGS---QWGLNLQYKVQPSPDGLAQAFI---IGEEFIGADDCALVLGDNIFYGHD 118 Query: 161 ITRALE 166 + + +E Sbjct: 119 LPKLME 124 >1MC3-A nrPDB Length = 296 Score = 53.7 bits (127), Expect = 3e-07, Method: Composition-based stats. Identities = 13/52 (25%), Positives = 27/52 (51%) Query: 43 LQAVLVADSFDRRFFPISKDQPRVLLPLANVALIDYTLEFLTATGVQETFVF 94 ++ +++A R PI++ + LLP+ + +I Y L L G++E + Sbjct: 4 MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILII 55 >4IHG-A nrPDB Length = 348 Score = 52.9 bits (125), Expect = 5e-07, Method: Composition-based stats. Identities = 23/128 (17%), Positives = 48/128 (37%), Gaps = 20/128 (15%) Query: 345 GPEVSLGHGSILEENVLLGSGTVIGSNCFITNSV-IGPGCHIGDNVVL-DQTYLWQG--- 399 G V +G G + +N +G+G+ + +N I + + IG C I V+ + + Sbjct: 138 GDNVIIGAGCFVGKNSKIGAGSRLWANVTIYHEIQIGQNCLIQSGTVVGADGFGYANDRG 197 Query: 400 ----------VRVAAGAQIHQSLLCD-----NAEVKERVTLKPRSVLTSQVVVGPNITLP 444 V + +I D + + V + + + VV+G N + Sbjct: 198 NWVKIPQIGRVIIGDRVEIGACTTIDRGALDDTIIGNGVIIDNQCQIAHNVVIGDNTAVA 257 Query: 445 EGSVISLH 452 G +++ Sbjct: 258 GGVIMAGS 265 Score = 34.0 bits (76), Expect = 0.27, Method: Composition-based stats. Identities = 15/91 (16%), Positives = 34/91 (37%), Gaps = 13/91 (14%) Query: 410 QSLLCDNAEVKERVTLKPRSVLTSQVVVGPNITLPEGSVISLHPP-DAEEDEDDGEFSDD 468 +++ A++ V++ +V+ S V +G N+ + G + + A Sbjct: 110 SAVIDATAKLGNNVSIGANAVIESGVELGDNVIIGAGCFVGKNSKIGAGSRLWANVTI-- 167 Query: 469 SGADQEKDKVKMKG----YNPAEVGAAGKGY 495 ++++ + VGA G GY Sbjct: 168 ------YHEIQIGQNCLIQSGTVVGADGFGY 192 >3TWD-A nrPDB Length = 222 Score = 52.9 bits (125), Expect = 5e-07, Method: Composition-based stats. Identities = 31/121 (25%), Positives = 49/121 (40%), Gaps = 11/121 (9%) Query: 339 RHNIYRGPEVSLGHGSILEENVLLGSGTVIGSNCFITNSVIGPGCHIGDNVVLDQTYLWQ 398 R + G +V + I+E NV LG IG+ C I NSVIG C I V++ L Sbjct: 32 RGTLTHGRDVEIDTNVIIEGNVTLGHRVKIGTGCVIKNSVIGDDCEISPYTVVEDANLAA 91 Query: 399 GVRVAAGAQIH-QSLLCDNAEVKE-----RVTLKPRSVLT-----SQVVVGPNITLPEGS 447 + A++ + L + A V + L S +G N+ + G+ Sbjct: 92 ACTIGPFARLRPGAELLEGAHVGNFVEMKKARLGKGSKAGHLTYLGDAEIGDNVNIGAGT 151 Query: 448 V 448 + Sbjct: 152 I 152 >5IDS-A nrPDB Length = 302 Score = 52.1 bits (123), Expect = 8e-07, Method: Composition-based stats. Identities = 20/126 (15%), Positives = 47/126 (37%), Gaps = 9/126 (7%) Query: 44 QAVLVADSFDRRFFPISKDQPRVLLPLANVALIDYTLEFLTATGVQETFVFCC-WKAAQI 102 + +++A R P + + LLP+ + +I Y L L G+++ V + Sbjct: 13 KGIILAGGSGTRLHPATLAISKQLLPVYDKPMIYYPLSTLMLAGMRDVLVISTPQDTPRF 72 Query: 103 KEHLLKSKWCRPTSLNVVRIIT-SELYRSLGDVLRDVDAKALVRSDFLLVYGD-VISNIN 160 ++ L +N+ + S + + + + + + LV GD + + Sbjct: 73 QQLLGDGS---QWGMNLQYAVQPSPDGLAQAFI---IGEQFIGNAPSALVLGDNIYYGHD 126 Query: 161 ITRALE 166 L+ Sbjct: 127 FQPLLK 132 >4G3P-A nrPDB Length = 501 Score = 52.1 bits (123), Expect = 9e-07, Method: Composition-based stats. Identities = 71/449 (15%), Positives = 141/449 (31%), Gaps = 75/449 (16%) Query: 37 EEPPPPLQAVLVADSFDRRFFPISKDQPRVLLPLANVALIDYTLEFLTATGVQETFVFCC 96 P +++A R D P+VL LA +++ + L + Q V Sbjct: 7 MTFPGDTAVLVLAAGPGTRMR---SDTPKVLHTLAGRSMLSHVLHAIAKLAPQRLIVVLG 63 Query: 97 WKAAQIKEHLLKSKWCRPTSLNVVRIITSELYRSLGDVLRDVDA-KALVRSDFLLVYGDV 155 +I L + + + + VL + A + ++ GD Sbjct: 64 HDHQRI--APLVGELADTLGRTIDVALQDRPLGTGHAVLCGLSALPDDYAGNVVVTSGDT 121 Query: 156 ISNINITRALEEHRLRRKLEKNVSVMTMIFKESSPSHPTRCHEDNVVVAVDSTTNRVLHF 215 ++ + R + V+V+T + +D+ V+A+ T+ Sbjct: 122 PL-LDADTLADLIATHRAVSAAVTVLTTTLDDPFGYGRILRTQDHEVMAIVEQTDATPSQ 180 Query: 216 QKTQGLRR--FAFPLSLFQGSSDGVEVRYDLLDCHISICSPQVAQLFTDNFDYQTRDDFV 273 ++ + + +AF ++ + + + + V + + Sbjct: 181 REIREVNAGVYAFDIAALRSALSRLSSNN----AQQELYLTDVIAILRSD---------- 226 Query: 274 RGLLVNEEILGNQIHM-HVTAKEYGARVSNLHMYSAVCADVIRRWVYPLTPEANFTDSTT 332 G +H HV A V+N + + +++ RR V Sbjct: 227 ----------GQTVHASHVDDSALVAGVNNRVQLAELASELNRRVVAA--------HQLA 268 Query: 333 QSCTHSRHNIYRGPEVSLGHGSILEENVLLGSGTVIGSNCFITNSVIGPGCHIGDNVVLD 392 + +V++G +++ L T IG G C +G + L Sbjct: 269 GVTVVDPATTWIDVDVTIGRDTVIHPGTQLLGRTQIG----------GR-CVVGPDTTLT 317 Query: 393 QTYLWQGVRVAAGAQI-----HQSLLCDNAEVKERVTLKPRSVLTSQVVVG-----PNIT 442 V V GA + S + D A V L+P + L + +G N T Sbjct: 318 ------DVAVGDGASVVRTHGSSSSIGDGAAVGPFTYLRPGTALGADGKLGAFVEVKNST 371 Query: 443 LPEGSVISLHPPDAE--EDEDDGEFSDDS 469 + G+ + P D D GE+S+ Sbjct: 372 IGTGTKV----PHLTYVGDADIGEYSNIG 396 >2QKX-A nrPDB Length = 391 Score = 51.7 bits (122), Expect = 1e-06, Method: Composition-based stats. Identities = 65/427 (15%), Positives = 133/427 (31%), Gaps = 69/427 (16%) Query: 37 EEPPPPLQAVLVADSFDRRFFPISKDQPRVLLPLANVALIDYTLEFLTATGVQETFVFCC 96 P +++A R D P+VL LA +++ + L + Q V Sbjct: 3 MTFPGDTAVLVLAAGPGTRMR---SDTPKVLHTLAGRSMLSHVLHAIAKLAPQRLIVVLG 59 Query: 97 WKAAQIKEHLLKSKWCRPTSLNVVRIITSELYRSLGDVLRDVDA-KALVRSDFLLVYGDV 155 +I L + + + + VL + A + ++ GD Sbjct: 60 HDHQRI--APLVGELADTLGRTIDVALQDRPLGTGHAVLCGLSALPDDYAGNVVVTSGDT 117 Query: 156 ISNINITRALEEHRLRRKLEKNVSVMTMIFKESSPSHPTRCHEDNVVVAVDSTTNRVLHF 215 ++ + R + V+V+T + +D+ V+A+ T+ Sbjct: 118 PL-LDADTLADLIATHRAVSAAVTVLTTTLDDPFGYGRILRTQDHEVMAIVEQTDATPSQ 176 Query: 216 QKTQGLRR--FAFPLSLFQGSSDGVEVRYDLLDCHISICSPQVAQLFTDNFDYQTRDDFV 273 ++ + + +AF ++ + + + + V + + Sbjct: 177 REIREVNAGVYAFDIAALRSALSRLSSNN----AQQELYLTDVIAILRSD---------- 222 Query: 274 RGLLVNEEILGNQIHM-HVTAKEYGARVSNLHMYSAVCADVIRRWVYPLTPEANFTDSTT 332 G +H HV A V+N + + +++ RR V Sbjct: 223 ----------GQTVHASHVDDSALVAGVNNRVQLAELASELNRRVVAA--------HQLA 264 Query: 333 QSCTHSRHNIYRGPEVSLGHGSILEENVLLGSGTVIGSNCFITNSVIGPGCHIGDNVVLD 392 + +V++G +++ L T IG G C +G + L Sbjct: 265 GVTVVDPATTWIDVDVTIGRDTVIHPGTQLLGRTQIG----------GR-CVVGPDTTLT 313 Query: 393 QTYLWQGVRVAAGAQI-----HQSLLCDNAEVKERVTLKPRSVLTSQVVVG-----PNIT 442 V V GA + S + D A V L+P + L + +G N T Sbjct: 314 ------DVAVGDGASVVRTHGSSSSIGDGAAVGPFTYLRPGTALGADGKLGAFVEVKNST 367 Query: 443 LPEGSVI 449 + G+ + Sbjct: 368 IGTGTKV 374 >3ZLK-A nrPDB Length = 303 Score = 51.3 bits (121), Expect = 1e-06, Method: Composition-based stats. Identities = 21/107 (19%), Positives = 38/107 (35%), Gaps = 3/107 (2%) Query: 44 QAVLVADSFDRRFFPISKDQPRVLLPLANVALIDYTLEFLTATGVQETFVFCC-WKAAQI 102 + +++A R P + + LLP+ + +I Y L L G++E + + Sbjct: 14 KGIILAGGSGTRLHPATLAISKQLLPVYDKPMIYYPLSTLMLAGIREILIISTPQDTPRF 73 Query: 103 KEHLLKSK-WCRPTSLNVVRIITS-ELYRSLGDVLRDVDAKALVRSD 147 ++ L W V +G+ D ALV D Sbjct: 74 QQLLGDGSNWGLDLQYAVQPSPDGLAQAFLIGESFIGNDLSALVLGD 120 >1XHD-A nrPDB Length = 173 Score = 51.3 bits (121), Expect = 2e-06, Method: Composition-based stats. Identities = 21/129 (16%), Positives = 46/129 (35%), Gaps = 18/129 (13%) Query: 343 YRGPEVSLGHGSILEE------NVLLGSGTVIGSNCFITN----SVIGPGCHIGDNVVLD 392 Y+ + + + + + +V +G + I N I ++IG ++ D L Sbjct: 8 YKEKKPKIASSAFIADYVTITGDVYVGEESSIWFNTVIRGDVSPTIIGDRVNVQDQCTLH 67 Query: 393 QT-----YLWQGVRVAAGAQIHQSLLCDNAEVKERVTLKPRSVLTSQVVVGPNITLPEGS 447 Q+ L V V +H + +A + + + + +G + +G Sbjct: 68 QSPQYPLILEDDVTVGHQVILHSCHIKKDALIGMGSIILDGAEIGEGAFIGAGSLVSQGK 127 Query: 448 VISLHPPDA 456 I PP+ Sbjct: 128 KI---PPNT 133 >4ECM-A nrPDB Length = 269 Score = 50.2 bits (118), Expect = 3e-06, Method: Composition-based stats. Identities = 21/136 (15%), Positives = 54/136 (39%), Gaps = 6/136 (4%) Query: 42 PLQAVLVADSFDRRFFPISKDQPRVLLPLANVALIDYTLEFLTATGVQETFVFCC-WKAA 100 ++ +++A R +PI+K + LLP+ +I + + L + + + Sbjct: 24 AMKGIILAGGTGSRLYPITKVTNKHLLPVGRYPMIYHAVYKLKQCDITDIMIITGKEHMG 83 Query: 101 QIKEHLLKSKWCRPTSLNVVRIITSELYRSLGDVLRDVDAKALVRSDFLLVYGDVISNIN 160 + L + + V+ + ++LG + + +++ GD I + + Sbjct: 84 DVVSFLGSGQEFGVSFTYRVQDKAGGIAQALG-----LCEDFVGNDRMVVILGDNIFSDD 138 Query: 161 ITRALEEHRLRRKLEK 176 I +EE +++ K Sbjct: 139 IRPYVEEFTNQKEGAK 154 >4E79-A nrPDB Length = 357 Score = 49.8 bits (117), Expect = 4e-06, Method: Composition-based stats. Identities = 20/100 (20%), Positives = 44/100 (44%), Gaps = 3/100 (3%) Query: 360 VLLGSGTVIGSNCFITNSVIGPGCHIGDNVVLDQTY-LWQGVRVAAGAQIH-QSLLCDNA 417 VL+G+ IGSNC I + + D V++D + V + + I + + + Sbjct: 206 VLIGNDVRIGSNCSIDRGAL-DNTILEDGVIIDNLVQIAHNVHIGSNTAIAAKCGIAGST 264 Query: 418 EVKERVTLKPRSVLTSQVVVGPNITLPEGSVISLHPPDAE 457 ++ + L + + + N+TL S+++ + +A Sbjct: 265 KIGKNCILAGACGVAGHLSIADNVTLTGMSMVTKNISEAG 304 Score = 47.1 bits (110), Expect = 3e-05, Method: Composition-based stats. Identities = 24/152 (15%), Positives = 49/152 (32%), Gaps = 38/152 (25%) Query: 346 PEVSLGHGSILEENVLLGSGTVIGSNCFIT-------NSVIGPGCHIGDNVVLD-QTYLW 397 P + + + V++G V+G N I N +G C I V + + L Sbjct: 113 PSAVISETAYIGHYVVIGENCVVGDNTVIQSHTKLDDNVEVGKDCFIDSYVTITGSSKLR 172 Query: 398 QGVRV-------AAG-------------AQIHQSLLCDNAEVKERVT----------LKP 427 VR+ G AQ+ L+ ++ + + L+ Sbjct: 173 DRVRIHSSTVIGGEGFGFAPYQGKWHRIAQLGSVLIGNDVRIGSNCSIDRGALDNTILED 232 Query: 428 RSVLTSQVVVGPNITLPEGSVISLHPPDAEED 459 ++ + V + N+ + + I+ A Sbjct: 233 GVIIDNLVQIAHNVHIGSNTAIAAKCGIAGST 264 Score = 42.1 bits (97), Expect = 0.001, Method: Composition-based stats. Identities = 22/85 (25%), Positives = 33/85 (38%), Gaps = 7/85 (8%) Query: 356 LEENVLLGSGTVIGSNCFITN-SVIGPGCHIGDNVVL-DQTYLWQGVRVAAGAQIHQSLL 413 +E + VI +I + VIG C +GDN V+ T L V V I + Sbjct: 105 IESTARIHPSAVISETAYIGHYVVIGENCVVGDNTVIQSHTKLDDNVEVGKDCFIDSYV- 163 Query: 414 CDNAEVKERVTLKPRSVLTSQVVVG 438 + L+ R + S V+G Sbjct: 164 ----TITGSSKLRDRVRIHSSTVIG 184 Score = 32.1 bits (71), Expect = 0.96, Method: Composition-based stats. Identities = 19/113 (16%), Positives = 48/113 (42%), Gaps = 8/113 (7%) Query: 389 VVLDQTYLWQGVRVAA-GAQIHQSLLCDNAEVKERVTLKPRSVLTSQVVVGPNITLPEGS 447 +++D YL + +I + + A + + + + VV+G N + + + Sbjct: 80 IIVDNPYLAFAILTHVFDKKISSTGIESTARIHPSAVISETAYIGHYVVIGENCVVGDNT 139 Query: 448 VISLHPP-----DAEEDEDDGEFSDDSGADQEKDKVKMKGYNPAEVGAAGKGY 495 VI H + +D + +G+ + +D+V++ ++ +G G G+ Sbjct: 140 VIQSHTKLDDNVEVGKDCFIDSYVTITGSSKLRDRVRI--HSSTVIGGEGFGF 190 >2UX8-A nrPDB Length = 297 Score = 49.4 bits (116), Expect = 5e-06, Method: Composition-based stats. Identities = 15/70 (21%), Positives = 30/70 (42%) Query: 37 EEPPPPLQAVLVADSFDRRFFPISKDQPRVLLPLANVALIDYTLEFLTATGVQETFVFCC 96 P +AV RF P +K P+ +LP+ + LI Y ++ G+++ Sbjct: 9 MTIKPLRKAVFPVAGLGTRFLPATKAMPKEMLPVVDRPLIQYAVDEAVEAGIEQMIFVTG 68 Query: 97 WKAAQIKEHL 106 + +++H Sbjct: 69 RGKSALEDHF 78 >3JUK-A nrPDB Length = 281 Score = 49.0 bits (115), Expect = 8e-06, Method: Composition-based stats. Identities = 15/61 (24%), Positives = 28/61 (45%) Query: 49 ADSFDRRFFPISKDQPRVLLPLANVALIDYTLEFLTATGVQETFVFCCWKAAQIKEHLLK 108 A + RF PI+K P+ +LP+ + LI Y +E G + + ++++ Sbjct: 9 AAGYGTRFLPITKTIPKEMLPIVDKPLIQYAVEEAMEAGCEVMAIVTGRNKRSLEDYFDT 68 Query: 109 S 109 S Sbjct: 69 S 69 >4MFG-A nrPDB Length = 168 Score = 47.5 bits (111), Expect = 2e-05, Method: Composition-based stats. Identities = 25/130 (19%), Positives = 54/130 (41%), Gaps = 15/130 (11%) Query: 320 PLTPEANFTDSTTQSCTHSRHNIYRGPEVSLGHGSILEEN---VLLGSGTVIGSNCFI-- 374 PL E+ F + N+ G + S+ + +++ + + +G T I + Sbjct: 13 PLIDESVFVAKSADVIG----NVKIGKDSSIWYNAVVRGDEGPITIGENTNIQDCSIVHG 68 Query: 375 -TNSVIGPGCHIGDNVVLDQTYLWQGVRVAAGAQIHQSLLCDNAEVKERVTLKPRSVLTS 433 T ++IG +G ++ + V + G S++ DNAE+ E + +++TS Sbjct: 69 DTETIIGNNVTVGHRSIVHGCKISDNVLIGMG-----SIILDNAEIGEYTLIGAGTLITS 123 Query: 434 QVVVGPNITL 443 P + + Sbjct: 124 NKKFPPGVLI 133 >1UG3-A nrPDB Length = 339 Score = 46.3 bits (108), Expect = 4e-05, Method: Composition-based stats. Identities = 40/207 (19%), Positives = 80/207 (38%), Gaps = 24/207 (11%) Query: 488 VGAAGKGYLWKAAGMNMEEEEELQQNLWGLKINMEEESESESEQSMDSEEPDSRGGSPQM 547 +G G LW+ AG++ +E Q++ + E E SE P R P Sbjct: 155 MGPKKVGTLWREAGLSWKEFLPEGQDIGAFVAEQKVEYTLGEE----SEAPGQRA-LPSE 209 Query: 548 DDIKVFQNEVLGTLQRGKEENISCDNLVLEINSLKYAYNISLKEVMQVL--SHVVLEFPL 605 + ++ L+ G D + ++ + N ++ +M + S ++ E PL Sbjct: 210 E----LNRQLEKLLKEGSSNQRVFDWIEANLSEQQIVSNTLVRALMTAVCYSAIIFETPL 265 Query: 606 QQMDSPLDSSRYCALLLPLLKAWSPVFRNYIKRAADHLEALAAIEDFFLEHEALGISMAK 665 + + +LKA + + + Y+ L+AL A++ + E + Sbjct: 266 RVDVA-------------VLKARAKLLQKYLCDEQKELQALYALQALVVTLEQPPNLLRM 312 Query: 666 VLMAFYQLEILAEETILSWFSQRDTTD 692 A Y +++ E+ SW S +D + Sbjct: 313 FFDALYDEDVVKEDAFYSWESSKDPAE 339 >2PA4-A nrPDB Length = 323 Score = 45.6 bits (106), Expect = 8e-05, Method: Composition-based stats. Identities = 20/97 (20%), Positives = 35/97 (36%) Query: 46 VLVADSFDRRFFPISKDQPRVLLPLANVALIDYTLEFLTATGVQETFVFCCWKAAQIKEH 105 V+ A RF P +K P+ LLP+ + I+ G + A + H Sbjct: 16 VVPAAGLGTRFLPATKTVPKELLPVVDTPGIELIAAEAAELGATRLAIITAPNKAGVLAH 75 Query: 106 LLKSKWCRPTSLNVVRIITSELYRSLGDVLRDVDAKA 142 +S T + + E+ R D+++ V Sbjct: 76 FERSSELEETLMERGKTDQVEIIRRAADLIKAVPVTQ 112 >4JD0-A nrPDB Length = 251 Score = 45.2 bits (105), Expect = 1e-04, Method: Composition-based stats. Identities = 30/199 (15%), Positives = 63/199 (31%), Gaps = 22/199 (11%) Query: 44 QAVLVADSFDRRFFPISKDQPRVLLPLANVALIDYTLEFLTATGVQETFVFCCWKAAQIK 103 +A+++A +R ++ D P+V L+ Y + L GV+ + + Sbjct: 13 EAIVLASGAGKRLRSVTGDVPKVFYRFDGCELVKYPMISLMKNGVERFVLVVSEGYRDLG 72 Query: 104 EHLLKSKWCRPTSLNVVRIITSELYRSLGDVLR-DVDAKALVRSDFLLVYGDVISNINIT 162 E +L L V I+ LG+ + + F L GD + + Sbjct: 73 EKVLND-------LGVEGIVVENKKVELGNAYSFFLSEPYVESEKFFLSCGDSL--FPPS 123 Query: 163 RALEEHRLRRKLEKNVSVMTMIFKESSPSHPTRC----HEDNVVVAVDSTTNRVLHFQKT 218 E + + K S P + +N +V + ++ +F Sbjct: 124 ALKSAFS-----EDEFHIKLGVSKRSDLIDPEKASKVLVNENRIVKIGKRIDQYNYFDTG 178 Query: 219 QGL---RRFAFPLSLFQGS 234 + + ++ S Sbjct: 179 VFVMTKKVYSLKESFSWTE 197 >2MZB-A nrPDB Length = 196 Score = 43.6 bits (101), Expect = 3e-04, Method: Composition-based stats. Identities = 29/155 (18%), Positives = 60/155 (38%), Gaps = 18/155 (11%) Query: 43 LQAVLVADSFDRRFFPISKDQPRVLLPLANVALIDYTLEFLTATGVQETFVFCCWKAAQI 102 + A+++A R + L+ L LIDY + L + V F+ + Sbjct: 1 MDALIMAGGKGTRM----GGVEKPLIKLCGRCLIDYVVSPLLKSKVNNIFIATSPNTPKT 56 Query: 103 KEHLLKSKWCRPTSLNVVRIITSELYRSLGDVLRDVDAK-ALVRSDFLLVYGDVIS--NI 159 KE++ S + ++ V+ S + D++ FL+V D+I+ + Sbjct: 57 KEYI-NSAYKDYKNIVVIDT-------SGKGYIEDLNECIGYFSEPFLVVSSDLINLKSK 108 Query: 160 NITRALEEH---RLRRKLEKNVSVMTMIFKESSPS 191 I ++ + + + ++VM K +PS Sbjct: 109 IINSIVDYFYCIKAKTPDVEALAVMIPKEKYPNPS 143 >6F1T-V nrPDB Length = 182 Score = 43.6 bits (101), Expect = 3e-04, Method: Composition-based stats. Identities = 18/140 (12%), Positives = 44/140 (31%), Gaps = 17/140 (12%) Query: 327 FTDSTTQSCTHSRHNIYRGPEVSLGHGSILEENVLLGSGTVI-GSNCFITNSVIGPGCHI 385 + + T S + + R + +L ++ + +I G + +G C + Sbjct: 7 LYNKSEYIETASGNKVSRQSVLCGSQNIVLNGKTIVMNDCIIRGDLANVR---VGRHCVV 63 Query: 386 GDNVVLDQTY-------------LWQGVRVAAGAQIHQSLLCDNAEVKERVTLKPRSVLT 432 V+ + + V + ++ + + V + + R VL Sbjct: 64 KSRSVIRPPFKKFSKGVAFFPLHIGDHVFIEEDCVVNAAQIGSYVHVGKNCVIGRRCVLK 123 Query: 433 SQVVVGPNITLPEGSVISLH 452 + N LP +V+ Sbjct: 124 DCCKILDNTVLPPETVVPPF 143 >5NW4-h nrPDB Length = 222 Score = 43.6 bits (101), Expect = 3e-04, Method: Composition-based stats. Identities = 18/140 (12%), Positives = 44/140 (31%), Gaps = 17/140 (12%) Query: 327 FTDSTTQSCTHSRHNIYRGPEVSLGHGSILEENVLLGSGTVI-GSNCFITNSVIGPGCHI 385 + + T S + + R + +L ++ + +I G + +G C + Sbjct: 47 LYNKSEYIETASGNKVSRQSVLCGSQNIVLNGKTIVMNDCIIRGDLANVR---VGRHCVV 103 Query: 386 GDNVVLDQTY-------------LWQGVRVAAGAQIHQSLLCDNAEVKERVTLKPRSVLT 432 V+ + + V + ++ + + V + + R VL Sbjct: 104 KSRSVIRPPFKKFSKGVAFFPLHIGDHVFIEEDCVVNAAQIGSYVHVGKNCVIGRRCVLK 163 Query: 433 SQVVVGPNITLPEGSVISLH 452 + N LP +V+ Sbjct: 164 DCCKILDNTVLPPETVVPPF 183 >3PMO-A nrPDB Length = 372 Score = 42.5 bits (98), Expect = 6e-04, Method: Composition-based stats. Identities = 36/232 (15%), Positives = 68/232 (29%), Gaps = 56/232 (24%) Query: 345 GPEVSLGHGSILEENVLLGSGTVIGSNCFIT-NSVIGPGCHIGDNVVLDQTYLWQGVRVA 403 +G G + + ++G+ +VIG ++ + IG V + V Sbjct: 147 ESGARIGAGVSIGAHCVIGARSVIGEGGWLAPRVTLYHDVTIGARVSIQSG----AVIGG 202 Query: 404 AG-------------AQIHQSLLCDNAEVKERVTLKPRS----VLTSQVVVGPNITLPEG 446 G AQI + D+ E+ T+ + ++ + V + I + Sbjct: 203 EGFGFANEKGVWQKIAQIGGVTIGDDVEIGANTTIDRGALSDTLIGNGVKLDNQIMIAHN 262 Query: 447 SVISLHPPDAEEDEDDGEFSDDSGADQEKDKVKMKGYNPAEVGAAGKG-YLWKAAGMNME 505 I H A G+A G + A G+ + Sbjct: 263 VQIGDHTAMA--------------------------ACVGISGSAKIGRHCMLAGGVGLV 296 Query: 506 EEEELQQNLW-------GLKINMEEESESESEQSMDSEEPDSRGGSPQMDDI 550 E+ N++ I S + +E S Q+DD+ Sbjct: 297 GHIEICDNVFVTGMTMVTRSITEPGSYSSGTAMQPAAEWKKSAARIRQLDDM 348 Score = 31.3 bits (69), Expect = 1.4, Method: Composition-based stats. Identities = 18/72 (25%), Positives = 32/72 (44%), Gaps = 6/72 (8%) Query: 379 IGPGCHIGDNVVLDQTYLWQGVRVAAGAQIH-QSLLCDNAEVKERVTLKPRSVLTSQVVV 437 + P +G V++ G R+ AG I ++ + + E L PR L V + Sbjct: 134 VDPSASVGAYAVIES-----GARIGAGVSIGAHCVIGARSVIGEGGWLAPRVTLYHDVTI 188 Query: 438 GPNITLPEGSVI 449 G +++ G+VI Sbjct: 189 GARVSIQSGAVI 200 >2WLD-A nrPDB Length = 215 Score = 42.5 bits (98), Expect = 6e-04, Method: Composition-based stats. Identities = 20/107 (18%), Positives = 41/107 (38%), Gaps = 12/107 (11%) Query: 356 LEENVLLGSG-TVIGSNCFITNSVIGPGCHIGDNVVLDQTYLWQGVRVAAGAQIHQS--- 411 ++ +G+G I I+ IG C + + T + + G +I+ Sbjct: 82 IQAKTTMGNGEITIAEKGKIS---IGKDCMLAHGYEIRNTDMHPIYSLENGERINHGKDV 138 Query: 412 LLCDNAEVKERVTLKPRSVLTSQVVVGPNITL-----PEGSVISLHP 453 ++ ++ + VT+ + + VVVG + L VI+ P Sbjct: 139 IIGNHVWLGRNVTILKGVCIPNNVVVGSHTVLYKSFKEPNCVIAGSP 185 >3TIO-A nrPDB Length = 183 Score = 42.5 bits (98), Expect = 7e-04, Method: Composition-based stats. Identities = 14/88 (15%), Positives = 31/88 (35%), Gaps = 5/88 (5%) Query: 362 LGSGTVIGSNCFITNSVIGPGCHIGDNVVLDQTYLWQGVRVAAGAQIHQSLLCDNAEVKE 421 +G+ T I + V + D L + + V V +H + + V Sbjct: 53 IGARTNIQDGSMLH--VTHKSSYNPDGNPLT---IGEDVTVGHKVMLHGCTIGNRVLVGM 107 Query: 422 RVTLKPRSVLTSQVVVGPNITLPEGSVI 449 L +++ V++G +P+ + Sbjct: 108 GSILLDGAIVEDDVMIGAGSLVPQNKRL 135 Score = 33.2 bits (74), Expect = 0.40, Method: Composition-based stats. Identities = 20/81 (24%), Positives = 38/81 (46%), Gaps = 7/81 (8%) Query: 324 EANFTDSTTQSCTHSRHN-IYRGPEVSLGH-----GSILEENVLLGSGTVIGSNCFITNS 377 + + T +S + N + G +V++GH G + VL+G G+++ + + Sbjct: 61 DGSMLHVTHKSSYNPDGNPLTIGEDVTVGHKVMLHGCTIGNRVLVGMGSILLDGAIVEDD 120 Query: 378 V-IGPGCHIGDNVVLDQTYLW 397 V IG G + N L+ YL+ Sbjct: 121 VMIGAGSLVPQNKRLESGYLY 141 >2X5Z-A nrPDB Length = 336 Score = 42.1 bits (97), Expect = 9e-04, Method: Composition-based stats. Identities = 24/110 (21%), Positives = 48/110 (43%), Gaps = 14/110 (12%) Query: 43 LQAVLVADSFDRRFFPI-SKDQPRVLLPL-ANVALIDYTLE-FLTATGVQETFVFCCWKA 99 ++A+++A RF+P+ + + P+ L L N +L+ +T E L ++ V Sbjct: 2 MKALILAGGSGERFWPLSTPETPKQFLKLFGNKSLMRWTFERVLEEMDPKDVIVV----- 56 Query: 100 AQIKEHLLKSKWCRPTSL--NVVRIITSE---LYRSLGDVLRDVDAKALV 144 K+++ ++K P N++ + +G L D D LV Sbjct: 57 -THKDYVERTKKELPELPDENIIAEPMKKNTAPACFIGTKLADDDEPVLV 105 >4R36-A nrPDB Length = 275 Score = 40.6 bits (93), Expect = 0.003, Method: Composition-based stats. Identities = 16/132 (12%), Positives = 45/132 (34%), Gaps = 21/132 (15%) Query: 342 IYRGPEVSLGHGSILEENVLLGSGTVIGSNCFI-------------------TNSVIGPG 382 +Y V +G + + N + G+ IG+ I + + IG Sbjct: 44 VYIDRNVVIGDNNKIMANANILYGSRIGNGNTIFPGAVIGAIPQDLKFKGEESTAEIGDN 103 Query: 383 CHIGDNVVLDQTYLWQGVRV--AAGAQIHQSLLCDNAEVKERVTLKPRSVLTSQVVVGPN 440 I +NV +++ +G + + + +A + + + + ++++ N Sbjct: 104 NLIRENVTINRGTAAKGRTIVGNNNLLMEGVHVAHDALIGNGCIVGNSTKMAGEIIIDDN 163 Query: 441 ITLPEGSVISLH 452 + ++ Sbjct: 164 AIISANVLMHQF 175 >2XWM-A nrPDB Length = 223 Score = 40.6 bits (93), Expect = 0.003, Method: Composition-based stats. Identities = 21/107 (19%), Positives = 39/107 (36%), Gaps = 13/107 (12%) Query: 45 AVLVADSFDRRFFPISKDQPRVLLPLANVALIDYTLEFLTATGVQETFVFCCWKAAQIKE 104 AV+ A R +P+ + L L+++ L L A+GV + V A + Sbjct: 5 AVVPAAGSGERLR---AGRPKAFVTLGGTPLLEHALSGLRASGVIDRIVIAVPPALTDES 61 Query: 105 HLLKSKWCRPTSLNVVRIITSELYRSLGDVLRDVDAKALVRSDFLLV 151 L+ +V+ + S+ L ++F+LV Sbjct: 62 KLVFGGED-----SVIVSGGVDRTESVALALEAA-----GDAEFVLV 98 >1OCX-A nrPDB Length = 182 Score = 40.2 bits (92), Expect = 0.003, Method: Composition-based stats. Identities = 32/168 (19%), Positives = 58/168 (34%), Gaps = 11/168 (6%) Query: 291 VTAKEYGARVSNLHMYSAVCADVIRRWVYPLTPEANFTDSTTQSCTHSRHNIYRGPEVS- 349 + + Y + L +I R+ + L E Y P Sbjct: 8 IAGELYRSADETLSRDRLRARQLIHRYNHSLAEEHTLRQQILADLFGQVTEAYIEPTFRC 67 Query: 350 -LGHGSILEENVLLGSGTVIGSNCFITNSVIGPGCHIGDNVVL-DQTYLWQGVRVAAGAQ 407 G+ L N V+ C I IG C + V + T+ V +GA+ Sbjct: 68 DYGYNIFLGNNFFANFDCVMLDVCPIR---IGDNCMLAPGVHIYTATHPIDPVARNSGAE 124 Query: 408 IHQSLLCDNAEVKERVTLKPRSVLTSQVVVGPNITLPEGSVISLHPPD 455 + + + + V + R+V+ V +G N+ + G+V++ PD Sbjct: 125 LGKPV-----TIGNNVWIGGRAVINPGVTIGDNVVVASGAVVTKDVPD 167 >4ISX-A nrPDB Length = 188 Score = 39.4 bits (90), Expect = 0.005, Method: Composition-based stats. Identities = 30/154 (19%), Positives = 59/154 (38%), Gaps = 19/154 (12%) Query: 315 RRWVYPLTPEANFTDSTTQSCTHSRHNIYRGPEVSLGHGSILEEN--VLLGSGTVIGSNC 372 R + LT ++T + R +I R S+G +E+N G +G N Sbjct: 27 REYCKKLT---RLFNNTLEDEYEKREDILRQLFGSVGKQINVEQNIRCDYGYNIHVGENF 83 Query: 373 F---------ITNSVIGPGCHIGDNVVLDQTYLWQGVRVAAGAQIHQSLLCDNAEVKERV 423 F + IG + NV + Y ++ + S + ++ + V Sbjct: 84 FANYDCIFLDVCKIEIGDNVMLAPNVQIYTAYHPIDAQLRNSGIEYGSPV----KIGDNV 139 Query: 424 TLKPRSVLTSQVVVGPNITLPEGSVISLH-PPDA 456 + ++T + +G N+ + GSV++ PP+ Sbjct: 140 WIGGGVIITPGITIGDNVVIGAGSVVTKDIPPNT 173 Score = 35.6 bits (80), Expect = 0.091, Method: Composition-based stats. Identities = 36/195 (18%), Positives = 59/195 (30%), Gaps = 39/195 (20%) Query: 222 RRFAFPLSLFQGSS--DGVEVRYDLLDCHISICSPQVAQLFTDNFDYQTRDDFVRGLLVN 279 R + L+ ++ D E R D+L Q+ N + R D+ + V Sbjct: 27 REYCKKLTRLFNNTLEDEYEKREDILRQLFGSVGKQI------NVEQNIRCDYGYNIHVG 80 Query: 280 EEILGNQ--IHMHVTAKEYGARVSNLHMYSAVCADVIRRWVYPLTPEANFTDSTTQSCTH 337 E N I + V E G V L P + + H Sbjct: 81 ENFFANYDCIFLDVCKIEIGDNVM-------------------LAP-----NVQIYTAYH 116 Query: 338 SRHNIYRGPEVSLGHGSILEENVLLGSGTVIGSNCFITNSVIGPGCHIGDNVVLDQTYLW 397 R + G + +NV +G G +I IG IG V+ + Sbjct: 117 PIDAQLRNSGIEYGSPVKIGDNVWIGGGVIITPGIT-----IGDNVVIGAGSVVTKDIPP 171 Query: 398 QGVRVAAGAQIHQSL 412 V V ++ + + Sbjct: 172 NTVAVGNPCRVIKKI 186 >5F42-A nrPDB Length = 280 Score = 39.0 bits (89), Expect = 0.007, Method: Composition-based stats. Identities = 18/102 (17%), Positives = 36/102 (35%), Gaps = 1/102 (0%) Query: 394 TYLWQGVRVAAGAQIHQ-SLLCDNAEVKERVTLKPRSVLTSQVVVGPNITLPEGSVISLH 452 + + ++A A I ++ N + E LK + V+G N + + + I Sbjct: 6 AVVHESAKIADSAIIGPFCVIGKNVVIGENTELKSHVTIGDNAVIGKNNRIFQYASIGDD 65 Query: 453 PPDAEEDEDDGEFSDDSGADQEKDKVKMKGYNPAEVGAAGKG 494 P D + D + ++ + G E+G G Sbjct: 66 PIDYTYKKGDFSQVVIGDNNIIRECATIHGGTAKEIGVTSVG 107 Score = 38.3 bits (87), Expect = 0.011, Method: Composition-based stats. Identities = 22/103 (21%), Positives = 38/103 (36%), Gaps = 5/103 (4%) Query: 346 PEVSLGHGSILEENVLLGSGTVIGSNCFITNSV-IGPGCHIGDNVVLDQTYLWQGVRVA- 403 + +I+ ++G VIG N + + V IG IG N + Q + Sbjct: 10 ESAKIADSAIIGPFCVIGKNVVIGENTELKSHVTIGDNAVIGKNNRIFQYASIGDDPIDY 69 Query: 404 --AGAQIHQSLLCDNAEVKERVTLKPRSVLTSQVV-VGPNITL 443 Q ++ DN ++E T+ + V VG N + Sbjct: 70 TYKKGDFSQVVIGDNNIIRECATIHGGTAKEIGVTSVGNNNII 112 Score = 31.7 bits (70), Expect = 1.0, Method: Composition-based stats. Identities = 13/87 (14%), Positives = 28/87 (32%), Gaps = 15/87 (17%) Query: 412 LLCDNAEVKERVTLKPRSVLTSQVVVGPNITLPEGSVISLHPPDAEEDEDDGEFSDDSGA 471 ++ A V E + +++ V+G N+ + E + + H D + Sbjct: 1 MIHSLAVVHESAKIADSAIIGPFCVIGKNVVIGENTELKSH-----VTIGDNAVIGKNNR 55 Query: 472 DQEKDKVKMKGYNPAEVGAAGKGYLWK 498 + A +G Y +K Sbjct: 56 IFQY----------ASIGDDPIDYTYK 72 >2CU2-A nrPDB Length = 337 Score = 38.3 bits (87), Expect = 0.011, Method: Composition-based stats. Identities = 15/42 (35%), Positives = 25/42 (59%), Gaps = 2/42 (4%) Query: 45 AVLVADSFDRRFFPISK-DQPRVLLPL-ANVALIDYTLEFLT 84 A+++A R +P+S+ D+P+ LPL L++ TLE L Sbjct: 5 ALVMAGGRGERLWPLSREDRPKPFLPLFEGKTLLEATLERLA 46 >6FYY-m nrPDB Length = 405 Score = 38.3 bits (87), Expect = 0.013, Method: Composition-based stats. Identities = 38/214 (17%), Positives = 84/214 (39%), Gaps = 24/214 (11%) Query: 504 MEEEEELQQNLWGLKINMEEESESESE--QSMDSEEPDSRGGSPQMDDIKVFQNEV-LGT 560 E+E+EL + + +E+ + E M E +R +++ +E Sbjct: 196 DEDEDELSRQIKAAASTLEDIEVKDDEWAVDMSEEAIRARAKELEVNSELTQLDEYGEWI 255 Query: 561 LQRGKEENISCDNLVLEINSLKYAYNI-SLKEVMQVLSHVVLEFPLQQMDSPLDSSRYCA 619 L++ E+ + + V E+ ++ + ++ VL+ + + + + ++ Sbjct: 256 LEQAGEDKENLPSDV-ELYKKAAELDVLNDPKIGCVLAQCLFDEDIVNEIAEHNAFFTKI 314 Query: 620 LLLPLLKAWSPVFRNYIKRAADHLEALAAIEDFF-LEHEALGISMAKVLMAFYQLEILAE 678 L+ P + + IE F LEH+ L + K+L+ Y +I++E Sbjct: 315 LVTPEYEK----------------NFMGGIERFLGLEHKDLIPLLPKILVQLYNNDIISE 358 Query: 679 ETILSW--FSQRDTTDKGQQLRKNQQLQRFIQWL 710 E I+ + S + K + + + FI WL Sbjct: 359 EEIMRFGTKSSKKFVPKEVSKKVRRAAKPFITWL 392 >2IUA-A nrPDB Length = 374 Score = 37.9 bits (86), Expect = 0.017, Method: Composition-based stats. Identities = 16/104 (15%), Positives = 35/104 (33%), Gaps = 11/104 (10%) Query: 350 LGHGSILEENVLLGSGTVIGSNCFIT-NSVIGPGCHIGDNVVLDQTYLWQGVRVAAGA-- 406 +G + ++G+ + +G + +I VI IG V++ + Sbjct: 157 VGSACHIGSGSVIGAYSTVGEHSYIHPRVVIRERVSIGKRVIIQPGAVIGSCGFGYVTSA 216 Query: 407 --------QIHQSLLCDNAEVKERVTLKPRSVLTSQVVVGPNIT 442 + + ++ D+ E+ T+ S V G I Sbjct: 217 FGQHKHLKHLGKVIIEDDVEIGANTTIDRGRFKHSVVREGSKID 260 >3R0S-A nrPDB Length = 266 Score = 37.1 bits (84), Expect = 0.028, Method: Composition-based stats. Identities = 20/143 (13%), Positives = 49/143 (34%), Gaps = 35/143 (24%) Query: 343 YRGPEVSLGHGSILEENVLLGSGTVIGSNCFI--------------------TNSVIGPG 382 Y + +G+ ++++ + S T IG + + + VIG Sbjct: 30 YVSKDAKIGNNVVIKQGARILSDTTIGDHSRVFSYAIVGDIPQDISYKEEQKSGVVIGKN 89 Query: 383 CHIGDNVVL--------------DQTYLWQGVRVAAGAQIHQSLL-CDNAEVKERVTLKP 427 I + + D ++ +A + +++ +NA + V L Sbjct: 90 ATIREFATINSGTAKGDGFTRIGDNAFIMAYCHIAHDCLLGNNIILANNATLAGHVELGD 149 Query: 428 RSVLTSQVVVGPNITLPEGSVIS 450 +V+ + + + EG +I+ Sbjct: 150 FTVVGGLTPIHQFVKVGEGCMIA 172 >1KRR-A nrPDB Length = 203 Score = 36.7 bits (83), Expect = 0.034, Method: Composition-based stats. Identities = 26/152 (17%), Positives = 46/152 (30%), Gaps = 22/152 (14%) Query: 323 PEANFTDSTTQSCTHSRHNIYRGPEVSLGHG--SILEENVLLGSGTVIGSNCFITNSVIG 380 PE T + H SL + + EN + I IG Sbjct: 23 PEKRLRGKTLMYEFNHSHPSEVEKRESLIKEMFATVGENAWVEPPVYFSYGSNIH---IG 79 Query: 381 PGCHIGDNVVLDQTY---LWQGVRVAAGAQI-------HQSLLCDN------AEVKERVT 424 + N+ + Y + V +A + H L + + V Sbjct: 80 RNFYANFNLTIVDDYTVTIGDNVLIAPNVTLSVTGHPVHHELRKNGEMYSFPITIGNNVW 139 Query: 425 LKPRSVLTSQVVVGPNITLPEGSVISLH-PPD 455 + V+ V +G N + GS+++ PP+ Sbjct: 140 IGSHVVINPGVTIGDNSVIGAGSIVTKDIPPN 171 >3R8Y-A nrPDB Length = 240 Score = 36.3 bits (82), Expect = 0.046, Method: Composition-based stats. Identities = 16/77 (20%), Positives = 27/77 (35%), Gaps = 16/77 (20%) Query: 348 VSLGHGSILEENVLLGSGTVIGSNCFIT-------NSVIGPGCHIGDNVVL--------- 391 V +G +++ N + G VIG I + +G CH+G VL Sbjct: 104 VEIGDNAVIMMNATINIGAVIGEGSMIDMNAVLGGRATVGKNCHVGAGAVLAGVIEPPSA 163 Query: 392 DQTYLWQGVRVAAGAQI 408 + V + A + Sbjct: 164 KPVIVEDDVVIGANVVV 180 >3Q1X-A nrPDB Length = 313 Score = 36.3 bits (82), Expect = 0.050, Method: Composition-based stats. Identities = 21/110 (19%), Positives = 37/110 (33%), Gaps = 17/110 (15%) Query: 362 LGSGTVIGSNCFITNSV---IGPGCHIGDNVVLDQTYLW-------QGVRVAAGAQIHQS 411 + G I + FI + V IG IG+ + Q+ +G + G + Sbjct: 166 IHPGASIKGHFFIDHGVGVVIGETAIIGEWCRIYQSVTLGAMHFQEEGGVIKRGTK-RHP 224 Query: 412 LLCDNAEVKERVTLKPRSVLTSQVVVGPNITLPEG------SVISLHPPD 455 + D + + ++ S V +G N + IS HP Sbjct: 225 TVGDYVTIGTGAKVLGNIIVGSHVRIGANCWIDRDVDSNQTVYISEHPTH 274 >3T57-A nrPDB Length = 305 Score = 35.9 bits (81), Expect = 0.069, Method: Composition-based stats. Identities = 15/95 (15%), Positives = 31/95 (32%), Gaps = 6/95 (6%) Query: 349 SLGHGSILEENVLLGSGTVIGSNCFITNSVIGPGCHIGDNVVL-DQTYLWQGVRVAAGAQ 407 +GH +++ G CF+ IG I + + + + Sbjct: 85 IIGHHAVVGVKCQDLKY-KHGDECFL---CIGNNNEIREFCSIHRSSKPSDKTVIGDNNL 140 Query: 408 I-HQSLLCDNAEVKERVTLKPRSVLTSQVVVGPNI 441 I + + ++ +R ++L VVV N Sbjct: 141 IMGSCHIAHDCKIGDRNIFANNTLLAGHVVVEDNT 175 Score = 31.7 bits (70), Expect = 1.0, Method: Composition-based stats. Identities = 24/130 (18%), Positives = 44/130 (33%), Gaps = 32/130 (24%) Query: 346 PEVSLGHGSILEENVLLGSGTVIGSNCFITNSV-IGPGCHIGDNVVL-DQTYLWQGVRVA 403 P + +++ + V +G IGS+ + N + P H+ N L + L G V Sbjct: 12 PSAVVHPNAVIGKGVSVGPYCTIGSSVKLGNGCKLYPSSHVFGNTELGESCVLMTGAVVG 71 Query: 404 A----------GAQIHQ------------------SLLC--DNAEVKERVTLKPRSVLTS 433 I LC +N E++E ++ S + Sbjct: 72 DELPGYTFIGCNNIIGHHAVVGVKCQDLKYKHGDECFLCIGNNNEIREFCSIHRSSKPSD 131 Query: 434 QVVVGPNITL 443 + V+G N + Sbjct: 132 KTVIGDNNLI 141 >5DEP-A nrPDB Length = 258 Score = 35.6 bits (80), Expect = 0.073, Method: Composition-based stats. Identities = 24/122 (19%), Positives = 47/122 (38%), Gaps = 16/122 (13%) Query: 347 EVSLGHGSILEENVLLGSGTVIGSNCFITN-SVIGPGCHIGDNVVL-------------D 392 +V +G SI+ V +G GTVIG + + + IG I + Sbjct: 19 DVQVGPWSIVGAEVEIGEGTVIGPHVVLKGPTKIGKHNRIYQFSSVGEDTPDLKYKGEPT 78 Query: 393 QTYLWQGVRVAAGAQIHQSLLCDNAE--VKERVTLKPRSVLTSQVVVGPNITLPEGSVIS 450 + + + G IH+ + D AE + + + + + V+G + L + ++ Sbjct: 79 RLVIGDHNVIREGVTIHRGTVQDRAETTIGDHNLIMAYAHIGHDSVIGNHCILVNNTALA 138 Query: 451 LH 452 H Sbjct: 139 GH 140 >2JF2-A nrPDB Length = 264 Score = 35.6 bits (80), Expect = 0.074, Method: Composition-based stats. Identities = 16/80 (20%), Positives = 30/80 (37%), Gaps = 14/80 (17%) Query: 367 VIGSNCFITNSV-IGPGCHIG--------DNVVLDQTYLWQGVRVAAGAQIHQSLLCDNA 417 IG I SV I G G DN+++ ++ V + +L +NA Sbjct: 87 EIGDRNRIRESVTIHRGTVQGGGLTKVGSDNLLMINAHIAHDCTVGN-----RCILANNA 141 Query: 418 EVKERVTLKPRSVLTSQVVV 437 + V++ +++ V Sbjct: 142 TLAGHVSVDDFAIIGGMTAV 161 Score = 32.9 bits (73), Expect = 0.51, Method: Composition-based stats. Identities = 21/139 (15%), Positives = 46/139 (33%), Gaps = 34/139 (24%) Query: 345 GPEVSLGHGSILEENVLLGSGTVIGSNCFITNSV-------IGPG--------------- 382 S+G + + ++G IG + + V IG Sbjct: 17 EEGASIGANAHIGPFCIVGPHVEIGEGTVLKSHVVVNGHTKIGRDNEIYQFASIGEVNQD 76 Query: 383 ---------CHIGDNVVLDQTYLWQGVRVAAG--AQIHQ-SLLCDNAEVKERVTLKPRSV 430 IGD + ++ V G ++ +LL NA + T+ R + Sbjct: 77 LKYAGEPTRVEIGDRNRIRESVTIHRGTVQGGGLTKVGSDNLLMINAHIAHDCTVGNRCI 136 Query: 431 LTSQVVVGPNITLPEGSVI 449 L + + ++++ + ++I Sbjct: 137 LANNATLAGHVSVDDFAII 155 >1THJ-A nrPDB Length = 214 Score = 35.2 bits (79), Expect = 0.093, Method: Composition-based stats. Identities = 16/62 (25%), Positives = 24/62 (38%) Query: 324 EANFTDSTTQSCTHSRHNIYRGPEVSLGHGSILEENVLLGSGTVIGSNCFITNSVIGPGC 383 E + + +Y G VSL H S + +G T IG F+ S +G C Sbjct: 90 EGEPIEDNIVEVDGKEYAVYIGNNVSLAHQSQVHGPAAVGDDTFIGMQAFVFKSKVGNNC 149 Query: 384 HI 385 + Sbjct: 150 VL 151 Score = 30.9 bits (68), Expect = 2.1, Method: Composition-based stats. Identities = 40/200 (20%), Positives = 62/200 (31%), Gaps = 50/200 (25%) Query: 323 PEANFTDSTTQSCTHSRHNIYRGPEVSLGHGSILEENVLLGSGTVI----------GSNC 372 P A D T Y PE S+ + NV++ I G Sbjct: 24 PSAPVIDPTA----------YIDPEASVIGEVTIGANVMVSPMASIRSDEGMPIFVGDRS 73 Query: 373 FITNSVI----------------------GP--GCHIGDNVVLD-QTYLWQGVRVAAGAQ 407 + + V+ G +IG+NV L Q+ + V Sbjct: 74 NVQDGVVLHALETINEEGEPIEDNIVEVDGKEYAVYIGNNVSLAHQSQVHGPAAVGDDTF 133 Query: 408 IHQSLLCDNAEVKERVTLKPRSVLTSQVVVGPNITLPEGSVISLHPPDAEEDEDDGEFSD 467 I ++V L+PRS V + +P G V++ AE D+ E +D Sbjct: 134 IGMQAFVFKSKVGNNCVLEPRSA-AIGVTIPDGRYIPAGMVVT---SQAEADKL-PEVTD 188 Query: 468 DSGADQEKDKVKMKGYNPAE 487 D + V + AE Sbjct: 189 DYAYSHTNEAVVYVNVHLAE 208 >3CJ8-A nrPDB Length = 236 Score = 34.4 bits (77), Expect = 0.16, Method: Composition-based stats. Identities = 19/91 (20%), Positives = 36/91 (39%), Gaps = 10/91 (10%) Query: 328 TDSTTQSCTHSRHNIYRGPEVSLGHGSILEENVLLGSGTVIGSNCFIT-NSVIGPGCHIG 386 ++ + R + G + + G+IL ++G+GT+I + + +G CHIG Sbjct: 90 INARIEPGALIREKVEIGDQAVIMMGAILNIGAVVGAGTMIDMGAVLGGRATVGKHCHIG 149 Query: 387 DNVVLDQTY---------LWQGVRVAAGAQI 408 VL + V + A A + Sbjct: 150 AGTVLAGVIEPPSAAPVVIENEVVIGANAVV 180 >5AFU-U nrPDB Length = 168 Score = 34.4 bits (77), Expect = 0.18, Method: Composition-based stats. Identities = 23/127 (18%), Positives = 40/127 (31%), Gaps = 23/127 (18%) Query: 346 PEVSLGHGSILEENVLLGSGTVIGSNCFITNS----VIGPGCHIGDNVVLDQTY------ 395 P + S + +V +G TVI I VIG G I + ++ Y Sbjct: 1 PGAVVCVESEIRGDVTIGPRTVIHPKARIIAEAGPIVIGEGNLIEEQALIINAYPDNITP 60 Query: 396 -------LWQGVRVAAGAQIH------QSLLCDNAEVKERVTLKPRSVLTSQVVVGPNIT 442 + G +++ A V V L ++ + + Sbjct: 61 DTEKPMIIGTNNVFEVGCYSQAMKMGDNNVIESKAYVGRNVILTSGCIIGACCNLNTFEV 120 Query: 443 LPEGSVI 449 +PE +VI Sbjct: 121 IPENTVI 127 Score = 31.3 bits (69), Expect = 1.7, Method: Composition-based stats. Identities = 13/42 (30%), Positives = 15/42 (35%), Gaps = 4/42 (9%) Query: 343 YRGPEVSLGHGSILEENVLLGSGTVIGSNCFITNSVIGPGCH 384 Y G V L G I+ L + VI N I G C Sbjct: 96 YVGRNVILTSGCIIGACCNLNTFEVIPENTVI----YGADCL 133 >1H7T-A nrPDB Length = 245 Score = 34.4 bits (77), Expect = 0.20, Method: Composition-based stats. Identities = 34/204 (16%), Positives = 70/204 (34%), Gaps = 29/204 (14%) Query: 46 VLVADSFDRRFFPISKDQPRVLLPLANVALIDYTLE-FLTATGVQETFVFCCWKAAQIKE 104 +++ + P + LL + +I + E L GV E +V ++++ Sbjct: 5 IVIPARYGSSRLP-----GKPLLDIVGKPMIQHVYERALQVAGVAEVWV--ATDDPRVEQ 57 Query: 105 HLLKSKWCRPTSLNVVRIITSELYRSLGDVLRDVDAKALVRSD-FLLVYGD--VISNINI 161 + I+T + S D R V+ V +D ++ + GD +I ++ Sbjct: 58 AVQAFGG--------KAIMTRNDHESGTD--RLVEVMHKVEADIYINLQGDEPMIRPRDV 107 Query: 162 TRALEEHRLRRKLEKNVSVMTMIFKESSPSHPTRCHEDNVVVAVDSTTNRVLHFQKTQGL 221 L+ R + + V T+ E + V V +T L+F ++ Sbjct: 108 ETLLQGMR----DDPALPVATLC----HAISAAEAAEPSTVKVVVNTRQDALYFSRSPIP 159 Query: 222 RRFAFPLSLFQGSSDGVEVRYDLL 245 + + R D+L Sbjct: 160 YPRNAEKARYLKHVGIYAYRRDVL 183 >4EQY-A nrPDB Length = 283 Score = 34.0 bits (76), Expect = 0.21, Method: Composition-based stats. Identities = 22/133 (16%), Positives = 43/133 (32%), Gaps = 46/133 (34%) Query: 346 PEVSLGHGSILEENVLLGSGTVIGSNCFIT-NSVIGPG---------------------- 382 V +G +I+ NV +G+ T IGS+ I ++ IG Sbjct: 39 ETVEVGPYAIVGSNVTIGARTTIGSHSVIEGHTTIGEDNRIGHYASVGGRPQDMKYKDEP 98 Query: 383 --CHIGDNVVL--------------------DQTYLWQGVRVAAGAQIH-QSLLCDNAEV 419 IGD + D ++ V + ++ +L NA++ Sbjct: 99 TRLVIGDRNTIREFTTIHTGTVQDAGVTTLGDDNWIMAYVHIGHDCRVGSHVVLSSNAQM 158 Query: 420 KERVTLKPRSVLT 432 V + +++ Sbjct: 159 AGHVEIGDWAIVG 171 >1J2Z-A nrPDB Length = 270 Score = 34.0 bits (76), Expect = 0.23, Method: Composition-based stats. Identities = 22/125 (17%), Positives = 41/125 (32%), Gaps = 28/125 (22%) Query: 343 YRGP--EVSLGHGSILEENVLLGSGTVIGSNCFITNSVIGPGCHIGDNVVLDQTYLWQGV 400 Y+G E+ +G +++ E ++ GT G I ++IG D+ L V Sbjct: 73 YKGEYSELIIGEDNLIREFCMINPGTEGG----IKKTLIG-----------DKNLLMAYV 117 Query: 401 RVAAGAQIHQSLLCDNAEVKERVTLKPRSVLTSQVVVGPNITLPEGSVISLHPPDAEEDE 460 VA + L L + +G + + + I A+ Sbjct: 118 HVAHDC-----------VIGSHCILANGVTLAGHIEIGDYVNIGGLTAIHQFVRIAKGCM 166 Query: 461 DDGEF 465 G+ Sbjct: 167 IAGKS 171 Score = 30.9 bits (68), Expect = 1.8, Method: Composition-based stats. Identities = 19/74 (25%), Positives = 29/74 (39%), Gaps = 11/74 (14%) Query: 362 LGSGTVIGSNCFITNSV-IGPGCHIGDNVVLDQTYLWQGVRVAAGAQIHQSLLCDNAEVK 420 + +I I V IG C IGD V LD +GV++ + V Sbjct: 4 IAKTAIISPKAEINKGVEIGEFCVIGDGVKLD-----EGVKLHNNVTLQGHTF-----VG 53 Query: 421 ERVTLKPRSVLTSQ 434 + + P +VL +Q Sbjct: 54 KNTEIFPFAVLGTQ 67 >3MQG-A nrPDB Length = 192 Score = 34.0 bits (76), Expect = 0.25, Method: Composition-based stats. Identities = 23/124 (18%), Positives = 45/124 (36%), Gaps = 26/124 (20%) Query: 351 GHGSILEENVLLGSGTVIGSNCFITNSV-------IGPGCHIGDNVVLDQTY-------L 396 GH + + ++ G IG++ I + V IG GC +G NV + + Sbjct: 1 GHMATIHPTAIVDEGARIGAHSRIWHWVHICGGAEIGEGCSLGQNVFVGNRVRIGNRVKI 60 Query: 397 WQGVRVAAGAQIHQSLLCD-----------NAEVKERVTLKPRSVLTSQVVVGPNITLPE 445 V V + + C A ++ + + +++ +G N T+ Sbjct: 61 QNNVSVYDNVFLEDDVFCGPSMVFTNVYNPRAAIERKSEYRD-TIVRQGATLGANCTVVC 119 Query: 446 GSVI 449 G+ I Sbjct: 120 GATI 123 >4CVH-A nrPDB Length = 411 Score = 33.6 bits (75), Expect = 0.27, Method: Composition-based stats. Identities = 14/45 (31%), Positives = 18/45 (40%), Gaps = 3/45 (6%) Query: 40 PPPLQAVLVADSFDRRFFPISKDQPRVLLPLANVALIDYTLEFLT 84 P + AVL A R P+ P+ LI YTL+ L Sbjct: 4 PQAVAAVLPAGGCGERM---GVPTPKQFCPILERPLISYTLQALE 45 >2NPO-A nrPDB Length = 207 Score = 33.6 bits (75), Expect = 0.31, Method: Composition-based stats. Identities = 24/155 (15%), Positives = 50/155 (32%), Gaps = 27/155 (17%) Query: 301 SNLHMYS---AVCADVIRRWVYPLTPEANFTDSTTQSCTHSRHNIYRGPEVSLGHGSILE 357 S L Y A+ + IR+ +Y E F + + +I+E Sbjct: 46 STLPKYDFFIAIGNNEIRKKIYQKISENGF-----------KIVNLIHKSALISPSAIVE 94 Query: 358 ENV--LLGSGTVIGSNCFITNSVIGPGCHIGDNVVLDQTYLWQGVRVAAGAQIH-QSLLC 414 EN L+ VI + I VI + + + + + + + Sbjct: 95 ENAGILIMPYVVINAKAKIEKGVI----------LNTSSVIEHECVIGEFSHVSVGAKCA 144 Query: 415 DNAEVKERVTLKPRSVLTSQVVVGPNITLPEGSVI 449 N ++ + L S + + + + L G+ + Sbjct: 145 GNVKIGKNCFLGINSCVLPNLSLADDSILGGGATL 179 >5JXX-A nrPDB Length = 257 Score = 33.2 bits (74), Expect = 0.42, Method: Composition-based stats. Identities = 15/100 (15%), Positives = 37/100 (37%), Gaps = 7/100 (7%) Query: 345 GPEVSLGHGSILEENVLLGSGTVIGSNCFITNSVIGPGCHIGDNVVLD-QTYLWQGVRVA 403 + +I+ ++G + IG++ + + VI IG+N + ++Q + Sbjct: 10 DKSAMIADSAIIGPYCIVGKNSQIGAHTVLRSHVI-----IGENTKIGVHNDIYQFASIG 64 Query: 404 AGAQ-IHQSLLCDNAEVKERVTLKPRSVLTSQVVVGPNIT 442 Q + + E+ + ++ + V IT Sbjct: 65 ENPQDLKYAGEQTYLEIGDHNRIREACTIHRGTVQDRGIT 104 Score = 32.5 bits (72), Expect = 0.69, Method: Composition-based stats. Identities = 9/64 (14%), Positives = 26/64 (40%), Gaps = 1/64 (1%) Query: 393 QTYLWQGVRVAAGAQIH-QSLLCDNAEVKERVTLKPRSVLTSQVVVGPNITLPEGSVISL 451 + + +A A I ++ N+++ L+ ++ +G + + + + I Sbjct: 6 TAIIDKSAMIADSAIIGPYCIVGKNSQIGAHTVLRSHVIIGENTKIGVHNDIYQFASIGE 65 Query: 452 HPPD 455 +P D Sbjct: 66 NPQD 69 >3IGJ-A nrPDB Length = 190 Score = 32.9 bits (73), Expect = 0.46, Method: Composition-based stats. Identities = 20/130 (15%), Positives = 45/130 (34%), Gaps = 9/130 (6%) Query: 327 FTDSTTQSCTHSRHNIYRGPEVSLGHGSILEENVLLGSGTVIGSNCFITNSVIGPGCHIG 386 + S + I G+ + ++ VI C + IG C Sbjct: 52 LLNQLLGSSADGKAQINPDFRCDYGYNIHVGKSFFANFNCVILDVCEVR---IGDHCMFA 108 Query: 387 DNVVL-DQTYLWQGVRVAAGAQIHQSLLCDNAEVKERVTLKPRSVLTSQVVVGPNITLPE 445 V + T+ V +G + + + ++ V + +++ V +G N + Sbjct: 109 PGVHIYTATHPLHPVERNSGKEYGKPV-----KIGNNVWVGGGAIINPGVSIGDNAVIAS 163 Query: 446 GSVISLHPPD 455 G+V++ P+ Sbjct: 164 GAVVTKDVPN 173 >6F3A-U nrPDB Length = 190 Score = 32.9 bits (73), Expect = 0.48, Method: Composition-based stats. Identities = 19/113 (16%), Positives = 37/113 (32%), Gaps = 16/113 (14%) Query: 342 IYRGPEVSLGHGSILEENVLL-----GSGTVIGSNCFITNSVIGPGCHIGDNVVLDQTYL 396 I + +G G+++EE L+ + T + +IG Sbjct: 42 IAEAGPIVIGEGNLIEEQALIINAHPDNITPDAEDSEPKPMIIGTNNVFEVGC------Y 95 Query: 397 WQGVRVAAGAQIHQSLLCDNAEVKERVTLKPRSVLTSQVVVGPNITLPEGSVI 449 Q +++ I A V V L ++ + + +PE +VI Sbjct: 96 SQAMKMGDNNVIE-----SKAYVGRNVILTSGCIIGACCNLNTFEVIPENTVI 143 >4HSO-A nrPDB Length = 351 Score = 32.9 bits (73), Expect = 0.55, Method: Composition-based stats. Identities = 27/148 (18%), Positives = 50/148 (33%), Gaps = 28/148 (18%) Query: 30 GGARGAEEEPPPPLQAVLVADSFDRRFFPISKDQPRVLLPLANVALIDYTL--------- 80 G G + + A + A S F ++K ++ L Sbjct: 186 GFKNGTDGNLKIAIDA-IGAASHSHHFLGVTKAGHSAIVHTGGNPDCHVILRGGKEPNYD 244 Query: 81 --------EFLTATGVQETFVFCCWKAAQIKEHLLKSKWCRPTSLNVVRIITSELYRSLG 132 E L A GV + + C A K++ + + V + I ++L + G Sbjct: 245 AEHVSEAAEQLRAAGVTDKLMIDCSHANSRKDYTRQ--------MEVAQDIAAQLEQDGG 296 Query: 133 DVLRDVDAKALVRS--DFLLVYGDVISN 158 +++ + LV D VYG I++ Sbjct: 297 NIMGVMVESHLVEGRQDKPEVYGKSITD 324 >3F1C-A nrPDB Length = 246 Score = 32.5 bits (72), Expect = 0.64, Method: Composition-based stats. Identities = 25/125 (20%), Positives = 49/125 (39%), Gaps = 7/125 (5%) Query: 45 AVLVADSFDRRFFPISKDQPRVLLPLANVALIDYTLE-FLTATGVQETFVFCCWKAAQIK 103 A ++A R +S P+ LPL +I +T+E F+ T + + + Sbjct: 6 AQILAGGKGTRMGNVSM--PKQFLPLNGKPIIVHTVEKFILNTRFDKILI---SSPKEWM 60 Query: 104 EHLLKSKWCRPTSLNVVRIITSEL-YRSLGDVLRDVDAKALVRSDFLLVYGDVISNINIT 162 H + + +V I E ++ + +R V+ + D ++V D + Sbjct: 61 NHAEDNIKKYISDDRIVVIEGGEDRNETIMNGIRFVEKTYGLTDDDIIVTHDAVRPFLTH 120 Query: 163 RALEE 167 R +EE Sbjct: 121 RIIEE 125 >5JBE-A nrPDB Length = 854 Score = 31.7 bits (70), Expect = 1.1, Method: Composition-based stats. Identities = 15/63 (23%), Positives = 24/63 (38%), Gaps = 2/63 (3%) Query: 495 YLWKAAGMNMEEEEELQQNLWGLKINMEEESESE--SEQSMDSEEPDSRGGSPQMDDIKV 552 Y+ + + + +L ++ + E S S S QSM + PD G I V Sbjct: 110 YVIEQSIAANKGTSKLANDINSFAATVPELSASSELSLQSMPNYRPDKSGTIDSDQVIFV 169 Query: 553 FQN 555 N Sbjct: 170 NNN 172 >2P2O-A nrPDB Length = 185 Score = 31.3 bits (69), Expect = 1.5, Method: Composition-based stats. Identities = 9/35 (25%), Positives = 15/35 (42%) Query: 345 GPEVSLGHGSILEENVLLGSGTVIGSNCFITNSVI 379 G V +GH + ++ G IG N I + + Sbjct: 128 GKPVVIGHNVWIGGRAVINPGVTIGDNAVIASGAV 162 >5TXC-A nrPDB Length = 705 Score = 31.3 bits (69), Expect = 1.6, Method: Composition-based stats. Identities = 9/20 (45%), Positives = 15/20 (75%) Query: 52 FDRRFFPISKDQPRVLLPLA 71 +D RF P++ +PRVL P++ Sbjct: 209 YDERFHPLTGARPRVLEPIS 228 >3LKD-A nrPDB Length = 542 Score = 30.5 bits (67), Expect = 2.3, Method: Composition-based stats. Identities = 10/70 (14%), Positives = 24/70 (34%) Query: 631 VFRNYIKRAADHLEALAAIEDFFLEHEALGISMAKVLMAFYQLEILAEETILSWFSQRDT 690 V+R Y + H + LA I D ++ ++ E+ + + Sbjct: 69 VYRKYYEDEETHEDLLAVITDEMSYAIHPDLTFTALVERVNDGSFQLEDLAQGFRDIEQS 128 Query: 691 TDKGQQLRKN 700 + + L ++ Sbjct: 129 DELYENLFED 138 >4E6U-A nrPDB Length = 265 Score = 30.5 bits (67), Expect = 2.7, Method: Composition-based stats. Identities = 18/130 (13%), Positives = 40/130 (30%), Gaps = 22/130 (16%) Query: 345 GPEVSLGHGSILEENVLLGSGTVIGSNCFI-TNSVIGPGCHIGDNVVL------------ 391 P + + ++G IG+ + ++ V+G IG N + Sbjct: 17 DPSAVIASDVQIGPYCIIGPQVTIGAGTKLHSHVVVGGFTRIGQNNEIFQFASVGEVCQD 76 Query: 392 ---DQTYLW----QGVRVAAGAQIHQSLLCDNA--EVKERVTLKPRSVLTSQVVVGPNIT 442 W + +H+ + DNA ++ L + + +VG + Sbjct: 77 LKYKGEETWLEIGNNNLIREHCSLHRGTVQDNALTKIGSHNLLMVNTHIAHDCIVGDHNI 136 Query: 443 LPEGSVISLH 452 ++ H Sbjct: 137 FANNVGVAGH 146 >3SGI-A nrPDB Length = 615 Score = 30.2 bits (66), Expect = 3.4, Method: Composition-based stats. Identities = 13/87 (14%), Positives = 28/87 (32%), Gaps = 2/87 (2%) Query: 22 AGPGGSGGGGARGAEEEPPPPLQAVLVADSFD--RRFFPISKDQPRVLLPLANVALIDYT 79 A P S G R + + ++ F P + Q + L + + ++T Sbjct: 208 ANPRNSAAGSLRQKDPAVTARRRLRMICHGLGHVEGFRPATLHQAYLALRAWGLPVSEHT 267 Query: 80 LEFLTATGVQETFVFCCWKAAQIKEHL 106 GV+E + ++ + Sbjct: 268 TLATDLAGVRERIDYWGEHRHEVDHEI 294 >1ZAU-A nrPDB Length = 328 Score = 29.8 bits (65), Expect = 4.1, Method: Composition-based stats. Identities = 13/87 (14%), Positives = 28/87 (32%), Gaps = 2/87 (2%) Query: 22 AGPGGSGGGGARGAEEEPPPPLQAVLVADSFD--RRFFPISKDQPRVLLPLANVALIDYT 79 A P S G R + + ++ F P + Q + L + + ++T Sbjct: 208 ANPRNSAAGSLRQKDPAVTARRRLRMICHGLGHVEGFRPATLHQAYLALRAWGLPVSEHT 267 Query: 80 LEFLTATGVQETFVFCCWKAAQIKEHL 106 GV+E + ++ + Sbjct: 268 TLATDLAGVRERIDYWGEHRHEVDHEI 294 >3G0S-A nrPDB Length = 316 Score = 29.8 bits (65), Expect = 4.6, Method: Composition-based stats. Identities = 11/36 (30%), Positives = 19/36 (52%) Query: 129 RSLGDVLRDVDAKALVRSDFLLVYGDVISNINITRA 164 + G++ R K LV DF+L+ GD S ++ + Sbjct: 186 EATGNLTRVHQIKELVSDDFILLSGDDASALDFMQL 221 >6NVA-A nrPDB Length = 294 Score = 29.4 bits (64), Expect = 5.5, Method: Composition-based stats. Identities = 14/49 (28%), Positives = 24/49 (48%), Gaps = 1/49 (2%) Query: 116 SLNVVRIITSELYRSLGDVLRDVDAKALVRSDFLLVYGDVISNINITRA 164 L V+ I + + G++ R K LV DF+L+ GD S ++ + Sbjct: 152 RLAKVKNIIG-IXEATGNLTRVNQIKELVSDDFVLLSGDDASALDFMQL 199 >2YFN-A nrPDB Length = 720 Score = 29.0 bits (63), Expect = 7.0, Method: Composition-based stats. Identities = 21/106 (19%), Positives = 38/106 (35%), Gaps = 10/106 (9%) Query: 62 DQPRVLLPLANVALIDYTLEFLTATGVQETFVFCCWKA---------AQIKEHLLKSKWC 112 +Q R+LL L N L Y L V E + + I+ H+ +SK+ Sbjct: 267 NQTRLLLGL-NEELFSYPLASGETFTVPEVILSYSAEGLSALSQQYHNCIRNHVCRSKYV 325 Query: 113 RPTSLNVVRIITSELYRSLGDVLRDVDAKALVRSDFLLVYGDVISN 158 ++ + + GD + D+ +A ++V D Sbjct: 326 HMQRPVLINSWEAAYFDFTGDTIVDLAKEAASLGIDMVVMDDGWFG 371 >6G5I-z nrPDB Length = 568 Score = 28.6 bits (62), Expect = 9.5, Method: Composition-based stats. Identities = 15/64 (23%), Positives = 27/64 (42%), Gaps = 6/64 (9%) Query: 509 ELQQNLWGLKINME----EESESESEQSMDSEEPDSRGGSPQMDDIKVFQNEVLGTLQRG 564 E Q + + E S+++SE+ D P P +D K + +++ QR Sbjct: 487 ENQVEERTCSDSEDIGSSECSDTDSEEQGDHARPKKHTTDPDID--KKERKKMVKEAQRE 544 Query: 565 KEEN 568 K +N Sbjct: 545 KRKN 548 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.309 0.122 0.293 Lambda K H 0.267 0.0376 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 22,376,206 Number of Sequences: 36641 Number of extensions: 827187 Number of successful extensions: 3524 Number of sequences better than 10.0: 110 Number of HSP's better than 10.0 without gapping: 104 Number of HSP's successfully gapped in prelim test: 86 Number of HSP's that attempted gapping in prelim test: 3045 Number of HSP's gapped (non-prelim): 362 length of query: 721 length of database: 10,336,785 effective HSP length: 104 effective length of query: 617 effective length of database: 6,526,121 effective search space: 4026616657 effective search space used: 4026616657 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 62 (28.6 bits)