BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q12884 (760 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 1Z68-A nrPDB 1500 0.0 2GBG-A nrPDB 837 0.0 2AJB-A nrPDB 836 0.0 2QT9-A nrPDB 835 0.0 4WJL-A nrPDB 457 e-129 1XFD-A nrPDB 428 e-120 5OLJ-A nrPDB 320 2e-87 2ECF-A nrPDB 209 3e-54 5YP1-A nrPDB 191 8e-49 2EEP-A nrPDB 166 3e-41 4Q1V-A nrPDB 151 1e-36 6EOT-A nrPDB 142 7e-34 6EOR-A nrPDB 134 2e-31 4HXF-B nrPDB 60 4e-09 5L8S-A nrPDB 54 2e-07 3O4I-A nrPDB 52 1e-06 3AZQ-A nrPDB 49 1e-05 6IGR-A nrPDB 44 2e-04 5UW6-A nrPDB 44 4e-04 3WYD-A nrPDB 37 0.028 4WY5-A nrPDB 37 0.039 3FCX-A nrPDB 33 0.49 3DYV-A nrPDB 32 0.87 2XE4-A nrPDB 30 2.7 3KSR-A nrPDB 30 3.3 4AMY-A nrPDB 30 3.3 1C5K-A nrPDB 30 3.5 5XZO-A nrPDB 30 4.1 5T88-A nrPDB 29 6.2 5IYD-S nrPDB 29 6.3 4F7W-A nrPDB 29 7.0 1GME-A nrPDB 29 7.1 6C26-A nrPDB 29 9.5 2BKL-A nrPDB 29 9.8 >1Z68-A nrPDB Length = 719 Score = 1500 bits (3883), Expect = 0.0, Method: Compositional matrix adjust. Identities = 719/719 (100%), Positives = 719/719 (100%) Query: 39 MRALTLKDILNGTFSYKTFFPNWISGQEYLHQSADNNIVLYNIETGQSYTILSNRTMKSV 98 MRALTLKDILNGTFSYKTFFPNWISGQEYLHQSADNNIVLYNIETGQSYTILSNRTMKSV Sbjct: 1 MRALTLKDILNGTFSYKTFFPNWISGQEYLHQSADNNIVLYNIETGQSYTILSNRTMKSV 60 Query: 99 NASNYGLSPDRQFVYLESDYSKLWRYSYTATYYIYDLSNGEFVRGNELPRPIQYLCWSPV 158 NASNYGLSPDRQFVYLESDYSKLWRYSYTATYYIYDLSNGEFVRGNELPRPIQYLCWSPV Sbjct: 61 NASNYGLSPDRQFVYLESDYSKLWRYSYTATYYIYDLSNGEFVRGNELPRPIQYLCWSPV 120 Query: 159 GSKLAYVYQNNIYLKQRPGDPPFQITFNGRENKIFNGIPDWVYEEEMLATKYALWWSPNG 218 GSKLAYVYQNNIYLKQRPGDPPFQITFNGRENKIFNGIPDWVYEEEMLATKYALWWSPNG Sbjct: 121 GSKLAYVYQNNIYLKQRPGDPPFQITFNGRENKIFNGIPDWVYEEEMLATKYALWWSPNG 180 Query: 219 KFLAYAEFNDTDIPVIAYSYYGDEQYPRTINIPYPKAGAKNPVVRIFIIDTTYPAYVGPQ 278 KFLAYAEFNDTDIPVIAYSYYGDEQYPRTINIPYPKAGAKNPVVRIFIIDTTYPAYVGPQ Sbjct: 181 KFLAYAEFNDTDIPVIAYSYYGDEQYPRTINIPYPKAGAKNPVVRIFIIDTTYPAYVGPQ 240 Query: 279 EVPVPAMIASSDYYFSWLTWVTDERVCLQWLKRVQNVSVLSICDFREDWQTWDCPKTQEH 338 EVPVPAMIASSDYYFSWLTWVTDERVCLQWLKRVQNVSVLSICDFREDWQTWDCPKTQEH Sbjct: 241 EVPVPAMIASSDYYFSWLTWVTDERVCLQWLKRVQNVSVLSICDFREDWQTWDCPKTQEH 300 Query: 339 IEESRTGWAGGFFVSTPVFSYDAISYYKIFSDKDGYKHIHYIKDTVENAIQITSGKWEAI 398 IEESRTGWAGGFFVSTPVFSYDAISYYKIFSDKDGYKHIHYIKDTVENAIQITSGKWEAI Sbjct: 301 IEESRTGWAGGFFVSTPVFSYDAISYYKIFSDKDGYKHIHYIKDTVENAIQITSGKWEAI 360 Query: 399 NIFRVTQDSLFYSSNEFEEYPGRRNIYRISIGSYPPSKKCVTCHLRKERCQYYTASFSDY 458 NIFRVTQDSLFYSSNEFEEYPGRRNIYRISIGSYPPSKKCVTCHLRKERCQYYTASFSDY Sbjct: 361 NIFRVTQDSLFYSSNEFEEYPGRRNIYRISIGSYPPSKKCVTCHLRKERCQYYTASFSDY 420 Query: 459 AKYYALVCYGPGIPISTLHDGRTDQEIKILEENKELENALKNIQLPKEEIKKLEVDEITL 518 AKYYALVCYGPGIPISTLHDGRTDQEIKILEENKELENALKNIQLPKEEIKKLEVDEITL Sbjct: 421 AKYYALVCYGPGIPISTLHDGRTDQEIKILEENKELENALKNIQLPKEEIKKLEVDEITL 480 Query: 519 WYKMILPPQFDRSKKYPLLIQVYGGPCSQSVRSVFAVNWISYLASKEGMVIALVDGRGTA 578 WYKMILPPQFDRSKKYPLLIQVYGGPCSQSVRSVFAVNWISYLASKEGMVIALVDGRGTA Sbjct: 481 WYKMILPPQFDRSKKYPLLIQVYGGPCSQSVRSVFAVNWISYLASKEGMVIALVDGRGTA 540 Query: 579 FQGDKLLYAVYRKLGVYEVEDQITAVRKFIEMGFIDEKRIAIWGWSYGGYVSSLALASGT 638 FQGDKLLYAVYRKLGVYEVEDQITAVRKFIEMGFIDEKRIAIWGWSYGGYVSSLALASGT Sbjct: 541 FQGDKLLYAVYRKLGVYEVEDQITAVRKFIEMGFIDEKRIAIWGWSYGGYVSSLALASGT 600 Query: 639 GLFKCGIAVAPVSSWEYYASVYTERFMGLPTKDDNLEHYKNSTVMARAEYFRNVDYLLIH 698 GLFKCGIAVAPVSSWEYYASVYTERFMGLPTKDDNLEHYKNSTVMARAEYFRNVDYLLIH Sbjct: 601 GLFKCGIAVAPVSSWEYYASVYTERFMGLPTKDDNLEHYKNSTVMARAEYFRNVDYLLIH 660 Query: 699 GTADDNVHFQNSAQIAKALVNAQVDFQAMWYSDQNHGLSGLSTNHLYTHMTHFLKQCFS 757 GTADDNVHFQNSAQIAKALVNAQVDFQAMWYSDQNHGLSGLSTNHLYTHMTHFLKQCFS Sbjct: 661 GTADDNVHFQNSAQIAKALVNAQVDFQAMWYSDQNHGLSGLSTNHLYTHMTHFLKQCFS 719 >2GBG-A nrPDB Length = 730 Score = 837 bits (2161), Expect = 0.0, Method: Compositional matrix adjust. Identities = 395/730 (54%), Positives = 530/730 (72%), Gaps = 13/730 (1%) Query: 40 RALTLKDILNGTFSYKTFFPNWISGQEYLHQSADNNIVLYNIETGQSYTILSNRTMK--S 97 R TL D L TF K++ W+S EYL++ +NNI+L+N E G S L N T + Sbjct: 2 RTYTLADYLKNTFRVKSYSLRWVSDSEYLYKQ-ENNILLFNAEHGNSSIFLENSTFEIFG 60 Query: 98 VNASNYGLSPDRQFVYLESDYSKLWRYSYTATYYIYDLSNGEFVRGNELPRPIQYLCWSP 157 + S+Y +SPDR FV LE +Y K WR+SYTA+Y IYDL+ + + ++P Q++ WS Sbjct: 61 DSISDYSVSPDRLFVLLEYNYVKQWRHSYTASYSIYDLNKRQLITEEKIPNNTQWITWSQ 120 Query: 158 VGSKLAYVYQNNIYLKQRPGDPPFQITFNGRENKIFNGIPDWVYEEEMLATKYALWWSPN 217 G KLAYV++N+IY+K P P +IT G+EN IFNGI DWVYEEE+ ALWWSPN Sbjct: 121 EGHKLAYVWKNDIYVKIEPHLPSHRITSTGKENVIFNGINDWVYEEEIFGAYSALWWSPN 180 Query: 218 GKFLAYAEFNDTDIPVIAYSYYGDE--QYPRTINIPYPKAGAKNPVVRIFIIDTTYPAYV 275 G FLAYA+FNDT +P+I YS+Y DE QYP+T+ IPYPKAGA NP V+ FI++T + Sbjct: 181 GTFLAYAQFNDTGVPLIEYSFYSDESLQYPKTVWIPYPKAGAVNPTVKFFIVNTDSLSST 240 Query: 276 G---PQEVPVPAMIASSDYYFSWLTWVTDERVCLQWLKRVQNVSVLSICDFREDWQTWDC 332 P ++ PA + + D+Y + WV+++R+ LQWL+R+QN SV++ICD+ + W+C Sbjct: 241 TTTIPMQITAPASVTTGDHYLCDVAWVSEDRISLQWLRRIQNYSVMAICDYDKTTLVWNC 300 Query: 333 PKTQEHIEESRTGWAGGFFVSTPVFSYDAISYYKIFSDKDGYKHI-HYIKDTVENAIQ-- 389 P TQEHIE S TGW G F + P F+ D S+YKI SDKDGYKHI + KD + Sbjct: 301 PTTQEHIETSATGWCGRFRPAEPHFTSDGSSFYKIVSDKDGYKHICQFQKDRKPEQVCTF 360 Query: 390 ITSGKWEAINIFRVTQDSLFYSSNEFEEYPGRRNIYRISIGSYPPSKKCVTCHLRKERCQ 449 IT G WE I+I +T D L+Y SNE++E PG RN+Y+I + + +KKC++C L ERCQ Sbjct: 361 ITKGAWEVISIEALTSDYLYYISNEYKEMPGGRNLYKIQLTDHT-NKKCLSCDLNPERCQ 419 Query: 450 YYTASFSDYAKYYALVCYGPGIPISTLHDGRTDQEIKILEENKELENALKNIQLPKEEIK 509 YY+ S S AKYY L C GPG+P+ TLH +E+++LE+N L+ L+++Q+P +++ Sbjct: 420 YYSVSLSKEAKYYQLGCRGPGLPLYTLHRSTDQKELRVLEDNSALDKMLQDVQMPSKKLD 479 Query: 510 KLEVDEITLWYKMILPPQFDRSKKYPLLIQVYGGPCSQSVRSVFAVNWISYLASKEGMVI 569 + ++E WY+MILPP FD+SKKYPLLI VY GPCSQ + F +NW +YLAS E +++ Sbjct: 480 FIVLNETRFWYQMILPPHFDKSKKYPLLIDVYAGPCSQKADAAFRLNWATYLASTENIIV 539 Query: 570 ALVDGRGTAFQGDKLLYAVYRKLGVYEVEDQITAVRKFIEMGFIDEKRIAIWGWSYGGYV 629 A DGRG+ +QGDK+++A+ ++LG EVEDQI A R+F++MGF+D KR+AIWGWSYGGYV Sbjct: 540 ASFDGRGSGYQGDKIMHAINKRLGTLEVEDQIEAARQFLKMGFVDSKRVAIWGWSYGGYV 599 Query: 630 SSLALASGTGLFKCGIAVAPVSSWEYYASVYTERFMGLPTKDDNLEHYKNSTVMARAEYF 689 +S+ L SG+G+FKCGIAVAPVS WEYY SVYTER+MGLPT +DNL+HY+NSTVM+RAE F Sbjct: 600 TSMVLGSGSGVFKCGIAVAPVSRWEYYDSVYTERYMGLPTPEDNLDHYRNSTVMSRAENF 659 Query: 690 RNVDYLLIHGTADDNVHFQNSAQIAKALVNAQVDFQAMWYSDQNHGL-SGLSTNHLYTHM 748 + V+YLLIHGTADDNVHFQ SAQI+KALV+A VDFQAMWY+D++HG+ S + H+Y+HM Sbjct: 660 KQVEYLLIHGTADDNVHFQQSAQISKALVDAGVDFQAMWYTDEDHGIASSTAHQHIYSHM 719 Query: 749 THFLKQCFSL 758 +HFL+QCFSL Sbjct: 720 SHFLQQCFSL 729 >2AJB-A nrPDB Length = 728 Score = 836 bits (2160), Expect = 0.0, Method: Compositional matrix adjust. Identities = 390/729 (53%), Positives = 528/729 (72%), Gaps = 10/729 (1%) Query: 38 TMRALTLKDILNGTFSYKTFFPNWISGQEYLHQSADNNIVLYNIETGQSYTILSNRTMKS 97 + R TL D L TF K + WIS EYL++ +NNI+L+N E G S L N T Sbjct: 1 SRRTYTLTDYLKSTFRVKFYTLQWISDHEYLYKQ-ENNILLFNAEYGNSSIFLENSTFDE 59 Query: 98 VNAS--NYGLSPDRQFVYLESDYSKLWRYSYTATYYIYDLSNGEFVRGNELPRPIQYLCW 155 + S +Y +SPDRQF+ E +Y K WR+SYTA+Y IYDL+ + + +P Q++ W Sbjct: 60 LGYSTNDYSVSPDRQFILFEYNYVKQWRHSYTASYDIYDLNKRQLITEERIPNNTQWITW 119 Query: 156 SPVGSKLAYVYQNNIYLKQRPGDPPFQITFNGRENKIFNGIPDWVYEEEMLATKYALWWS 215 SPVG KLAYV+ N+IY+K P +IT+ G+EN I+NG+ DWVYEEE+ + ALWWS Sbjct: 120 SPVGHKLAYVWNNDIYVKNEPNLSSQRITWTGKENVIYNGVTDWVYEEEVFSAYSALWWS 179 Query: 216 PNGKFLAYAEFNDTDIPVIAYSYYGDE--QYPRTINIPYPKAGAKNPVVRIFIIDT---T 270 PNG FLAYA+FNDT++P+I YS+Y DE QYP+T+ IPYPKAGA+NP V+ F++DT + Sbjct: 180 PNGTFLAYAQFNDTEVPLIEYSFYSDESLQYPKTVRIPYPKAGAENPTVKFFVVDTRTLS 239 Query: 271 YPAYVGPQEVPVPAMIASSDYYFSWLTWVTDERVCLQWLKRVQNVSVLSICDFREDWQTW 330 A V ++ PA + D+Y +TWVT+ER+ LQW++R QN S++ ICD+ E W Sbjct: 240 PNASVTSYQIVPPASVLIGDHYLCGVTWVTEERISLQWIRRAQNYSIIDICDYDESTGRW 299 Query: 331 DCPKTQEHIEESRTGWAGGFFVSTPVFSYDAISYYKIFSDKDGYKHIHYIKDTVENAIQI 390 ++HIE S TGW G F + P F+ D S+YKI S+++GYKHI + + N I Sbjct: 300 ISSVARQHIEISTTGWVGRFRPAEPHFTSDGNSFYKIISNEEGYKHICHFQTDKSNCTFI 359 Query: 391 TSGKWEAINIFRVTQDSLFYSSNEFEEYPGRRNIYRISIGSYPPSKKCVTCHLRKERCQY 450 T G WE I I +T D L+Y SNE + PG RN+YRI + Y C++C L ERCQY Sbjct: 360 TKGAWEVIGIEALTSDYLYYISNEHKGMPGGRNLYRIQLNDYT-KVTCLSCELNPERCQY 418 Query: 451 YTASFSDYAKYYALVCYGPGIPISTLHDGRTDQEIKILEENKELENALKNIQLPKEEIKK 510 Y+ASFS+ AKYY L C+GPG+P+ TLH +D+E+++LE+N L+ L+++Q+P +++ Sbjct: 419 YSASFSNKAKYYQLRCFGPGLPLYTLHSSSSDKELRVLEDNSALDKMLQDVQMPSKKLDV 478 Query: 511 LEVDEITLWYKMILPPQFDRSKKYPLLIQVYGGPCSQSVRSVFAVNWISYLASKEGMVIA 570 + + WY+MILPP FD+SKKYPLLI+VY GPCSQ V +VF ++W +YLAS E +++A Sbjct: 479 INLHGTKFWYQMILPPHFDKSKKYPLLIEVYAGPCSQKVDTVFRLSWATYLASTENIIVA 538 Query: 571 LVDGRGTAFQGDKLLYAVYRKLGVYEVEDQITAVRKFIEMGFIDEKRIAIWGWSYGGYVS 630 DGRG+ +QGDK+++A+ R+LG +EVEDQI A R+F +MGF+D+KRIAIWGWSYGGYV+ Sbjct: 539 SFDGRGSGYQGDKIMHAINRRLGTFEVEDQIEATRQFSKMGFVDDKRIAIWGWSYGGYVT 598 Query: 631 SLALASGTGLFKCGIAVAPVSSWEYYASVYTERFMGLPTKDDNLEHYKNSTVMARAEYFR 690 S+ L +G+G+FKCGIAVAPVS WEYY SVYTER+MGLPT +DNL++Y+NSTVM+RAE F+ Sbjct: 599 SMVLGAGSGVFKCGIAVAPVSKWEYYDSVYTERYMGLPTPEDNLDYYRNSTVMSRAENFK 658 Query: 691 NVDYLLIHGTADDNVHFQNSAQIAKALVNAQVDFQAMWYSDQNHGL-SGLSTNHLYTHMT 749 V+YLLIHGTADDNVHFQ SAQ++KALV+A VDFQ MWY+D++HG+ S ++ H+YTHM+ Sbjct: 659 QVEYLLIHGTADDNVHFQQSAQLSKALVDAGVDFQTMWYTDEDHGIASNMAHQHIYTHMS 718 Query: 750 HFLKQCFSL 758 HFLKQCFSL Sbjct: 719 HFLKQCFSL 727 >2QT9-A nrPDB Length = 766 Score = 835 bits (2156), Expect = 0.0, Method: Compositional matrix adjust. Identities = 390/750 (52%), Positives = 533/750 (71%), Gaps = 10/750 (1%) Query: 17 LALLVMCIVLRPSRVHNSEENTMRALTLKDILNGTFSYKTFFPNWISGQEYLHQSADNNI 76 + ++ + +VL ++ +T + TL D L T+ K + WIS EYL++ +NNI Sbjct: 18 VTIITVPVVLLNKGTDDATADTRKTYTLTDYLKNTYRLKLYSLRWISDHEYLYKQ-ENNI 76 Query: 77 VLYNIETGQSYTILSNRTMKSVNAS--NYGLSPDRQFVYLESDYSKLWRYSYTATYYIYD 134 +++N E G S L N T S +Y +SPD QF+ LE +Y K WR+SYTA+Y IYD Sbjct: 77 LVFNAEYGNSSVFLENSTFDEFGHSINDYSISPDGQFILLEYNYVKQWRHSYTASYDIYD 136 Query: 135 LSNGEFVRGNELPRPIQYLCWSPVGSKLAYVYQNNIYLKQRPGDPPFQITFNGRENKIFN 194 L+ + + +P Q++ WSPVG KLAYV+ N+IY+K P P ++IT+ G+E+ I+N Sbjct: 137 LNKRQLITEERIPNNTQWVTWSPVGHKLAYVWNNDIYVKIEPNLPSYRITWTGKEDIIYN 196 Query: 195 GIPDWVYEEEMLATKYALWWSPNGKFLAYAEFNDTDIPVIAYSYYGDE--QYPRTINIPY 252 GI DWVYEEE+ + ALWWSPNG FLAYA+FNDT++P+I YS+Y DE QYP+T+ +PY Sbjct: 197 GITDWVYEEEVFSAYSALWWSPNGTFLAYAQFNDTEVPLIEYSFYSDESLQYPKTVRVPY 256 Query: 253 PKAGAKNPVVRIFIIDTTYPAYVGPQ---EVPVPAMIASSDYYFSWLTWVTDERVCLQWL 309 PKAGA NP V+ F+++T + V ++ PA + D+Y +TW T ER+ LQWL Sbjct: 257 PKAGAVNPTVKFFVVNTDSLSSVTNATSIQITAPASMLIGDHYLCDVTWATQERISLQWL 316 Query: 310 KRVQNVSVLSICDFREDWQTWDCPKTQEHIEESRTGWAGGFFVSTPVFSYDAISYYKIFS 369 +R+QN SV+ ICD+ E W+C ++HIE S TGW G F S P F+ D S+YKI S Sbjct: 317 RRIQNYSVMDICDYDESSGRWNCLVARQHIEMSTTGWVGRFRPSEPHFTLDGNSFYKIIS 376 Query: 370 DKDGYKHIHYIKDTVENAIQITSGKWEAINIFRVTQDSLFYSSNEFEEYPGRRNIYRISI 429 +++GY+HI Y + ++ IT G WE I I +T D L+Y SNE++ PG RN+Y+I + Sbjct: 377 NEEGYRHICYFQIDKKDCTFITKGTWEVIGIEALTSDYLYYISNEYKGMPGGRNLYKIQL 436 Query: 430 GSYPPSKKCVTCHLRKERCQYYTASFSDYAKYYALVCYGPGIPISTLHDGRTDQEIKILE 489 Y C++C L ERCQYY+ SFS AKYY L C GPG+P+ TLH D+ +++LE Sbjct: 437 SDYT-KVTCLSCELNPERCQYYSVSFSKEAKYYQLRCSGPGLPLYTLHSSVNDKGLRVLE 495 Query: 490 ENKELENALKNIQLPKEEIKKLEVDEITLWYKMILPPQFDRSKKYPLLIQVYGGPCSQSV 549 +N L+ L+N+Q+P +++ + ++E WY+MILPP FD+SKKYPLL+ VY GPCSQ Sbjct: 496 DNSALDKMLQNVQMPSKKLDFIILNETKFWYQMILPPHFDKSKKYPLLLDVYAGPCSQKA 555 Query: 550 RSVFAVNWISYLASKEGMVIALVDGRGTAFQGDKLLYAVYRKLGVYEVEDQITAVRKFIE 609 +VF +NW +YLAS E +++A DGRG+ +QGDK+++A+ R+LG +EVEDQI A R+F + Sbjct: 556 DTVFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINRRLGTFEVEDQIEAARQFSK 615 Query: 610 MGFIDEKRIAIWGWSYGGYVSSLALASGTGLFKCGIAVAPVSSWEYYASVYTERFMGLPT 669 MGF+D KRIAIWGWSYGGYV+S+ L SG+G+FKCGIAVAPVS WEYY SVYTER+MGLPT Sbjct: 616 MGFVDNKRIAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSRWEYYDSVYTERYMGLPT 675 Query: 670 KDDNLEHYKNSTVMARAEYFRNVDYLLIHGTADDNVHFQNSAQIAKALVNAQVDFQAMWY 729 +DNL+HY+NSTVM+RAE F+ V+YLLIHGTADDNVHFQ SAQI+KALV+ VDFQAMWY Sbjct: 676 PEDNLDHYRNSTVMSRAENFKQVEYLLIHGTADDNVHFQQSAQISKALVDVGVDFQAMWY 735 Query: 730 SDQNHGL-SGLSTNHLYTHMTHFLKQCFSL 758 +D++HG+ S + H+YTHM+HF+KQCFSL Sbjct: 736 TDEDHGIASSTAHQHIYTHMSHFIKQCFSL 765 >4WJL-A nrPDB Length = 719 Score = 457 bits (1177), Expect = e-129, Method: Compositional matrix adjust. Identities = 248/732 (33%), Positives = 403/732 (55%), Gaps = 36/732 (4%) Query: 42 LTLKDILNGTFSYKTFFPNWISGQEYLHQSADNNIVLYNIETGQSYTILSNRTMKSVNAS 101 L+L+D+ F WI+ + +++S + +++ NIET + +L N T + AS Sbjct: 5 LSLEDLFRKDFVLHDPEARWINDTDVVYKSENGHVIKLNIETNATTLLLENTTFVTFKAS 64 Query: 102 NYGLSPDRQFVYLESDYSKLWRYSYTATYYIYDLSNGEFVRGNELPRP------IQYLCW 155 + +SPD ++V L D +++ YSYTA+Y IY++ E EL P +QY W Sbjct: 65 RHSVSPDLKYVLLAYDVKQIFHYSYTASYVIYNIHTREVW---ELNPPEVEDSVLQYAAW 121 Query: 156 SPVGSKLAYVYQNNIYLKQRPGDPPFQITFNGRENKIFNGIPDWVYEEEMLATKYALWWS 215 G +L Y+++NNIY + ++T +G+E IFNGI DW+YEEE+L + A WWS Sbjct: 122 GVQGQQLIYIFENNIYYQPDIKSSSLRLTSSGKEEIIFNGIADWLYEEELLHSHIAHWWS 181 Query: 216 PNGKFLAYAEFNDTDIPVIAYSYYGDEQYPRTINIPYPKAGAKNPVVRIFIIDTTYPAYV 275 P+G+ LA+ ND+ +P + + YP+ PYPKAG NP +++++++ P + Sbjct: 182 PDGERLAFLMINDSLVPTMVIPRFTGALYPKGKQYPYPKAGQMNPTIKLYVVNLYGPTHT 241 Query: 276 GPQEVPVPAMIASSDYYFSWLTWVTDERVCLQWLKRVQNVSVLSICDFREDWQTWDCPKT 335 E+ P S +YY + + WV++ + ++WL R QN+S+L++C+ T C K Sbjct: 242 --LELMPPDSFKSREYYITMVKWVSNTKTVVRWLNRAQNISILTVCE----TTTGACSKK 295 Query: 336 QEHIEESRTGWAGGFFVSTPVFSYDAISYYKIFSDKDGYK-HIHYI-------KDTVENA 387 E ++ PVFS D ++ K G + H+I K Sbjct: 296 YEMTSDTWLSQQN----EEPVFSRDGSKFFMTVPVKQGGRGEFHHIAMFLIQSKSEQITV 351 Query: 388 IQITSGKWEAINIF---RVTQDSLFYSSNEFEEYPGRRNIYRISIGSYPPSKKCVTCHLR 444 +TSG WE I I TQ F S+ E P R +Y S +++C++C+ Sbjct: 352 RHLTSGNWEVIKILAYDETTQKIYFLST---ESSPRGRQLYSASTEGLL-NRQCISCNFM 407 Query: 445 KERCQYYTASFSDYAKYYALVCYGPGIPISTLHDGRTDQEIKILEENKELENALKNIQLP 504 KE+C Y+ ASFS +++ L C GP +P+ +LH + ILE N L+ A+ ++ Sbjct: 408 KEQCTYFDASFSPMNQHFLLFCEGPRVPVVSLHSTDNPAKYFILESNSMLKEAILKKKIG 467 Query: 505 KEEIKKLEVDEITLWYKMILPPQFDRSKKYPLLIQVYGGPCSQSVRSVFAVNWISYLASK 564 K EIK L +D+ L ++ LP F +Y LL+ + P Q V F ++W S L Sbjct: 468 KPEIKILHIDDYELPLQLSLPKDFMDRNQYALLLIMDEEPGGQLVTDKFHIDWDSVLIDM 527 Query: 565 EGMVIALVDGRGTAFQGDKLLYAVYRKLGVYEVEDQITAVRKFIEMGFIDEKRIAIWGWS 624 + +++A DGRG+ FQG K+L ++R+LG EV+DQITAV+ +++ +ID KR++I+G Sbjct: 528 DNVIVARFDGRGSGFQGLKILQEIHRRLGSVEVKDQITAVKFLLKLPYIDSKRLSIFGKG 587 Query: 625 YGGYVSSLALASGTGLFKCGIAVAPVSSWEYYASVYTERFMGLPTKDDNLEHYKNSTVMA 684 YGGY++S+ L S LFKCG VAP++ + YAS ++ER++G+P+K+++ Y+ ++V+ Sbjct: 588 YGGYIASMILKSDEKLFKCGSVVAPITDLKLYASAFSERYLGMPSKEEST--YQAASVLH 645 Query: 685 RAEYFRNVDYLLIHGTADDNVHFQNSAQIAKALVNAQVDFQAMWYSDQNHGLSGLSTNHL 744 + + L+IHGTAD VHFQ+SA++ K L+ A V++ Y D+ H +S S HL Sbjct: 646 NVHGLKEENILIIHGTADTKVHFQHSAELIKHLIKAGVNYTMQVYPDEGHNVSEKSKYHL 705 Query: 745 YTHMTHFLKQCF 756 Y+ + F C Sbjct: 706 YSTILKFFSDCL 717 >1XFD-A nrPDB Length = 723 Score = 428 bits (1101), Expect = e-120, Method: Compositional matrix adjust. Identities = 239/741 (32%), Positives = 405/741 (54%), Gaps = 42/741 (5%) Query: 40 RALTLKDILNGTFSYKTFFPNWISGQEYLHQSADNNIVLYNIETGQSYTILSNRTMKSVN 99 + +T++D+ + F WIS E++++ + L+N+ET S ++ + ++S+ Sbjct: 3 KKVTVEDLFSEDFKIHDPEAKWISDTEFIYREQKGTVRLWNVETNTSTVLIEGKKIESLR 62 Query: 100 ASNYGLSPDRQFVYLESDYSKLWRYSYTATYYIYDLSNGEFVRGNELPRP------IQYL 153 A Y +SPDR++ + ++++SYT Y + + +G+ L P +QY Sbjct: 63 AIRYEISPDREYALFSYNVEPIYQHSYTGYYVLSKIPHGD---PQSLDPPEVSNAKLQYA 119 Query: 154 CWSPVGSKLAYVYQNNIYLKQRPGDPPFQITFNGRENKIFNGIPDWVYEEEMLATKYALW 213 W P G +L ++++NNIY G ++ G+E I+NG+ DW+YEEE+L T A W Sbjct: 120 GWGPKGQQLIFIFENNIYYCAHVGKQAIRVVSTGKEGVIYNGLSDWLYEEEILKTHIAHW 179 Query: 214 WSPNGKFLAYAEFNDTDIPVIAYSYYGDEQYPRTINIPYPKAGAKNPVVRIFIIDTTYPA 273 WSP+G LAYA ND+ +P++ Y YP YPKAG++NP + + +I P Sbjct: 180 WSPDGTRLAYAAINDSRVPIMELPTYTGSIYPTVKPYHYPKAGSENPSISLHVIGLNGPT 239 Query: 274 YVGPQEVPVPAMIASSDYYFSWLTWVTDERVCLQWLKRVQNVSVLSICDFREDWQTWDCP 333 + E+ P +YY + + W T +V + WL R QNVS+L++CD T C Sbjct: 240 H--DLEMMPPDDPRMREYYITMVKWATSTKVAVTWLNRAQNVSILTLCDA----TTGVC- 292 Query: 334 KTQEHIEESRTGWAGGFFVSTPVFSYDAISYYKIFSDKDGYKHIHY--------IKDTVE 385 T++H +ES W PVFS D ++ I + G + Y + + Sbjct: 293 -TKKHEDESE-AWLHRQ-NEEPVFSKDGRKFFFIRAIPQGGRGKFYHITVSSSQPNSSND 349 Query: 386 NAIQITSGKWEAINIFRVTQ--DSLFYSSNEFEEYPGRRNIYRI-SIGSYPPSKKCVTCH 442 N ITSG W+ I + + +++ S E + P RR +Y ++G++ +++C++C Sbjct: 350 NIQSITSGDWDVTKILAYDEKGNKIYFLSTE--DLPRRRQLYSANTVGNF--NRQCLSCD 405 Query: 443 LRKERCQYYTASFSDYAKYYALVCYGPGIPISTLHDGRTDQEIKILEENKELENALKNIQ 502 L E C Y++ASFS ++ L C GPG+P+ T+H+ +++ LE N+ ++ A+ + Q Sbjct: 406 L-VENCTYFSASFSHSMDFFLLKCEGPGVPMVTVHNTTDKKKMFDLETNEHVKKAINDRQ 464 Query: 503 LPKEEIKKLEVDEITLWYKMILPPQFDRSKKYPLLIQVYGGPCSQSVRSVFAVNWISYLA 562 +PK E + +E+D+ L +++ P F + YPLL+ V G P SQSV F V+W + + Sbjct: 465 MPKVEYRDIEIDDYNLPMQILKPATFTDTTHYPLLLVVDGTPGSQSVAEKFEVSWETVMV 524 Query: 563 SKEGMVIALVDGRGTAFQGDKLLYAVYRKLGVYEVEDQITAVRKFIEMGFIDEKRIAIWG 622 S G V+ DGRG+ FQG KLL+ V R+LG+ E +DQ+ AVR ++ +ID R+A++G Sbjct: 525 SSHGAVVVKCDGRGSGFQGTKLLHEVRRRLGLLEEKDQMEAVRTMLKEQYIDRTRVAVFG 584 Query: 623 WSYGGYVSSLAL-ASGTG---LFKCGIAVAPVSSWEYYASVYTERFMGLPTKDDNLEHYK 678 YGGY+S+ L A G F CG A++P++ ++ YAS ++ER++GL D+ Y+ Sbjct: 585 KDYGGYLSTYILPAKGENQGQTFTCGSALSPITDFKLYASAFSERYLGLHGLDNRA--YE 642 Query: 679 NSTVMARAEYFRNVDYLLIHGTADDNVHFQNSAQIAKALVNAQVDFQAMWYSDQNHGLSG 738 + V R +L+IH TAD+ +HFQ++A++ L+ + ++ Y D++H + Sbjct: 643 MTKVAHRVSALEEQQFLIIHPTADEKIHFQHTAELITQLIRGKANYSLQIYPDESHYFTS 702 Query: 739 LS-TNHLYTHMTHFLKQCFSL 758 S HLY + +F +CF + Sbjct: 703 SSLKQHLYRSIINFFVECFRI 723 >5OLJ-A nrPDB Length = 723 Score = 320 bits (820), Expect = 2e-87, Method: Compositional matrix adjust. Identities = 232/752 (30%), Positives = 365/752 (48%), Gaps = 56/752 (7%) Query: 16 VLALLVMCIVLRPSRVHNSEENTMRALTLKDILNGTF---SYKTFFPNWISGQEYLHQSA 72 +L ++ MC + + + + LK+I +G F S + G+ Y + Sbjct: 9 LLGIVTMCAMAQTGD---------KPVDLKEITSGMFYARSAGRGIRSMPDGEHYTEMNR 59 Query: 73 DNN-IVLYNIETGQS----YTILSNRTMKSVNASNYGLSPDRQFVYLESDYSKLWRYSYT 127 + IV YN +G++ ++I R NY +S + L +D ++R+SY Sbjct: 60 ERTAIVRYNYASGKAVDTLFSIERARECPFKQIQNYEVSSTGHHILLFTDMESIYRHSYR 119 Query: 128 ATYYIYDLSNGEFVRGNELPRPIQYLCWSPVGSKLAYVYQNNIYLKQRPGDPPFQITFNG 187 A Y YD+ +E + +SP G +A+V NNI++K+ D Q+T +G Sbjct: 120 AAVYDYDVRRNLVKPLSEHVGKVMIPTFSPDGRMVAFVRDNNIFIKKFDFDTEVQVTTDG 179 Query: 188 RENKIFNGIPDWVYEEEMLATKYALWWSPNGKFLAYAEFNDTDIPVIAYSYYGDEQYPRT 247 + N + NG DWVYEEE T + WS + FLA+ +++ +P Y D+ YP Sbjct: 180 QINSVLNGATDWVYEEEFGVTNL-MSWSADNAFLAFVRSDESAVPEYRMPMYEDKLYPED 238 Query: 248 INIPYPKAGAKNPVVRIFIIDTTYPAYVGPQEVPVPAMIASSDYYFSWLTWVTD-ERVCL 306 YPKAG KN V + + + V + ++ +D Y + + + + + + Sbjct: 239 YTYKYPKAGEKNSTVSLHLYN------VADRNTKSVSLPIDADGYIPRIAFTDNADELAV 292 Query: 307 QWLKRVQNVSVLSICDFREDWQTWDCPKTQEHIEESRTGWAGGFFVSTPVFSYDAISYYK 366 L R+QN DF+ + + +++ + ++ F+ A + Sbjct: 293 MTLNRLQN-------DFKMYYVHPKSLVPKLILQDMNKRYVDSDWIQALKFT--AGGGFA 343 Query: 367 IFSDKDGYKHIHYIKDTVENAIQITSGKWEAINIFRV-TQDSLFYSSNEFEEYPGRRNIY 425 S+KDG+ HI+ + +ITSG W+ ++ V ++FY S E E P RR +Y Sbjct: 344 YVSEKDGFAHIYLYDNKGVMHRRITSGNWDVTKLYGVDASGTVFYQSAE--ESPIRRAVY 401 Query: 426 RISIGSYPPSKKCVTCHLRKERCQYYTASFSDYAKYYALVCYGPGIP-ISTLHDGRTDQE 484 I K ++ ++ A FS YY P + ++ + +E Sbjct: 402 AIDAKG---RKTKLSLNVGTN-----DALFSGNYAYYINTYSSAATPTVVSVFRSKGAKE 453 Query: 485 IKILEENKELENALKNIQL-PKE--EIKKLEVDEITLWYKMILPPQFDRSKKYPLLIQVY 541 ++ LE+N L LK + PKE IK E+ W ++ P FD S+ YP+L+ Y Sbjct: 454 LRTLEDNVALRERLKAYRYNPKEFTIIKTQSALELNAW--IVKPIDFDPSRHYPVLMVQY 511 Query: 542 GGPCSQSVRSVFAVNWISYLASKEGMVIALVDGRGTAFQGDKLLYAVYRKLGVYEVEDQI 601 GP SQ V ++ +W YLASK G V+A VDGRGT +G++ Y +LGV+E +DQI Sbjct: 512 SGPNSQQVLDRYSFDWEHYLASK-GYVVACVDGRGTGARGEEWRKCTYMQLGVFESDDQI 570 Query: 602 TAVRKFIEMGFIDEKRIAIWGWSYGGYVSSLALASGTGLFKCGIAVAPVSSWEYYASVYT 661 A ++ ++D RI IWGWSYGGY + ++L G G FK GIAVAPV+ W +Y SVYT Sbjct: 571 AAATAIGQLPYVDAARIGIWGWSYGGYTTLMSLCRGNGTFKAGIAVAPVADWRFYDSVYT 630 Query: 662 ERFMGLPTKDDNLEHYKNSTVMARAEYFRNVDYLLIHGTADDNVHFQNSAQIAKALVNAQ 721 ERFM P +N YK S+ + A + + L++ G+ADDNVH QN+ +ALV A Sbjct: 631 ERFMRTPK--ENASGYKMSSALDVASQLQG-NLLIVSGSADDNVHLQNTMLFTEALVQAN 687 Query: 722 VDFQAMWYSDQNHGLSGLSTN-HLYTHMTHFL 752 + F Y D+NH + G +T HLYT FL Sbjct: 688 IPFDMAIYMDKNHSIYGGNTRYHLYTRKAKFL 719 >2ECF-A nrPDB Length = 741 Score = 209 bits (533), Expect = 3e-54, Method: Compositional matrix adjust. Identities = 174/622 (27%), Positives = 275/622 (44%), Gaps = 63/622 (10%) Query: 156 SPVGSKLAYVYQNNIYLKQRPGDPPFQITFNGRENKIFNGIPDWVYEEEMLATKYALWWS 215 SP G ++++ N+++ Q+T +G I NGI ++V +EEM WW+ Sbjct: 160 SPKGGFVSFIRGRNLWVIDLASGRQMQLTADG-STTIGNGIAEFVADEEM-DRHTGYWWA 217 Query: 216 PNGKFLAYAEFNDTDIPVIA-YSYYGDEQYPRTINIPYPKAGAKNPVVRIFIIDTTYPAY 274 P+ +AYA +++ +PV Y Y D I YP AG N V++ +I A Sbjct: 218 PDDSAIAYARIDESPVPVQKRYEVYADRT--DVIEQRYPAAGDANVQVKLGVISPAEQA- 274 Query: 275 VGPQEVPVPAMIASSDYYFSWLTWVTDERVCLQWLKRVQNVSVLSICDFREDWQTWDCPK 334 + + D Y + + W + + Q R Q L + Q + Sbjct: 275 ----QTQWIDLGKEQDIYLARVNWRDPQHLSFQRQSRDQKKLDLVEVTLASNQQ-----R 325 Query: 335 TQEHIEESRTGWAGGFFVSTPVFSYDAISYYKIFSDKDGYKHIHYIKDTVENAIQITSGK 394 H E+ W ++ F D + S++ G++H++ I D+ A +T G Sbjct: 326 VLAH--ETSPTWVP--LHNSLRFLDDGSILWS--SERTGFQHLYRI-DSKGKAAALTHGN 378 Query: 395 WEAINIFRVTQDSLFYSSNEFEEYPGRRNIYRISIGSYPPSKKCVTCHLRKERCQYYTAS 454 W + V + + E IY + + P + + ++AS Sbjct: 379 WSVDELLAVDEKAGLAYFRAGIESARESQIYAVPLQGGQPQRLSKAPGM-------HSAS 431 Query: 455 FSDYAKYYALVCYGPGIPISTLHDGRTDQEIKILEENKE-----LENALKNIQLP----K 505 F+ A Y + + + T +I++ N E +EN L + + P + Sbjct: 432 FARNASVY----------VDSWSNNSTPPQIELFRANGEKIATLVENDLADPKHPYARYR 481 Query: 506 EEIKKLEVDEIT-------LWYKMILPPQFDRSKKYPLLIQVYGGPCSQSVRSVFAVN-- 556 E + +E +T L Y +I P FD +K+YP+ + VYGGP SQ+V + Sbjct: 482 EAQRPVEFGTLTAADGKTPLNYSVIKPAGFDPAKRYPVAVYVYGGPASQTVTDSWPGRGD 541 Query: 557 --WISYLASKEGMVIALVDGRGTAFQGDKLLYAVYRKLGVYEVEDQITAVRKFIEMGFID 614 + YLA ++G V+ +D RGT +G A+Y K G EV DQ+ V + ++D Sbjct: 542 HLFNQYLA-QQGYVVFSLDNRGTPRRGRDFGGALYGKQGTVEVADQLRGVAWLKQQPWVD 600 Query: 615 EKRIAIWGWSYGGYVSSLALASGTGLFKCGIAVAPVSSWEYYASVYTERFMGLPTKDDNL 674 RI + GWS GGY++ + LA + + CG+A APV+ W Y S YTER+M LP ++D Sbjct: 601 PARIGVQGWSNGGYMTLMLLAKASDSYACGVAGAPVTDWGLYDSHYTERYMDLPARND-- 658 Query: 675 EHYKNSTVMARAEYFRNVDYLLIHGTADDNVHFQNSAQIAKALVNAQVDFQAMWYSDQNH 734 Y+ + V+ E R+ LLIHG ADDNV F NS + AL F+ M Y H Sbjct: 659 AGYREARVLTHIEGLRS-PLLLIHGMADDNVLFTNSTSLMSALQKRGQPFELMTYPGAKH 717 Query: 735 GLSGLSTNHLYTHMTHFLKQCF 756 GLSG H Y FL +C Sbjct: 718 GLSGADALHRYRVAEAFLGRCL 739 >5YP1-A nrPDB Length = 745 Score = 191 bits (486), Expect = 8e-49, Method: Compositional matrix adjust. Identities = 184/778 (23%), Positives = 314/778 (40%), Gaps = 74/778 (9%) Query: 15 AVLALLVMCIVLRPSRVHNSEENTMRALTLKDILNG-TFSYKTFFPNWISGQEYLHQSAD 73 A+ AL + V H +E+ T+ A+T L+G T + P+ + D Sbjct: 4 ALFALFALITVATALPAH-AEKLTLEAITGSAPLSGPTLTKPQIAPDGSRVTFLRGKDRD 62 Query: 74 NNIV---LYNIETGQSYTILSNRTM---KSVNASNYGLSPDRQFVYLES---DY-----S 119 N + Y+I +GQ+ ++ + + + V + +RQ + S DY Sbjct: 63 RNRLDLWEYDIASGQTRLLVDSSVVLPGEEVLSDEEKARRERQRIAALSGIVDYQWSPDG 122 Query: 120 KLWRYSYTATYYIYDLSNGEFVRGNELPRPIQYLC---WSPVGSKLAYVYQNNIYLKQRP 176 K + Y YDL+ +L + SP G ++++ N++ Sbjct: 123 KALLFPLGGELYFYDLTKSGRDAVRKLTNGGGFATDPKISPKGGFVSFIRDRNLWAIDLA 182 Query: 177 GDPPFQITFNGRENKIFNGIPDWVYEEEMLATKYALWWSPNGKFLAYAEFNDTDIPVIA- 235 Q+T +G + I NG+ ++V +EEM WW+P+ +A+A ++T +PV Sbjct: 183 SGKEVQLTRDG-SDTIGNGVAEFVADEEM-DRHTGYWWAPDDAAIAFARIDETPVPVQKR 240 Query: 236 YSYYGDEQYPRTINIPYPKAGAKNPVVRIFIIDTTYPAYVGPQEVPVPAMI---ASSDYY 292 Y Y D + YP AG N V++ +I P+ P I D Y Sbjct: 241 YEVYPDRT--EVVEQRYPAAGDHNVRVQLGVI--------APKTGARPRWIDLGKDPDIY 290 Query: 293 FSWLTWVTDERVCLQWLKRVQNVSVLSICDFREDWQTWDCPKTQEHIEESRTGWAGGFFV 352 + + W +R+ Q R Q L Q + + E+ T W Sbjct: 291 LARVDWRDPQRLTFQRQSRDQKKIELIETTLTNGTQ-------RTLVTETSTTW------ 337 Query: 353 STPVFSYDAISYYKI-----FSDKDGYKHIHYIKDTVENAIQITSGKWEAINIFRVTQDS 407 V ++ + + K S++ G++H++ + +T G+W ++ + + + Sbjct: 338 ---VPLHNDLRFLKDGRFLWSSERSGFEHLYVASEDGSTLTALTQGEWVVDSLLAIDEAA 394 Query: 408 LFYSSNEFEEYPGRRNIYRISIGSYPPSKKCVTCHLRKERCQYYTASF-----SDYAKYY 462 + + ++Y + + P + + + F SD Sbjct: 395 GLAYVSGTRDGATEAHVYAVPLSGGEPRRLTQAPGMHAATFARNASVFVDSWSSDTTLPQ 454 Query: 463 ALVCYGPGIPISTLHDGRTDQEIKILEENKELENALKNIQLPKEEIKKLEVDEIT-LWYK 521 + G ++TL + + + + P D T L Y Sbjct: 455 IELFKADGTKLATLL-------VNDVSDATHPYAKYRAAHQPTAYGTLTAADGTTPLHYS 507 Query: 522 MILPPQFDRSKKYPLLIQVYGGPCSQSVRSVFAVNWISYL---ASKEGMVIALVDGRGTA 578 +I P FD K+YP+++ VYGGP +Q+V + S+ +++G V+ +D RGT Sbjct: 508 LIKPAGFDPKKQYPVVVFVYGGPAAQTVTRAWPGRSDSFFNQYLAQQGYVVFTLDNRGTP 567 Query: 579 FQGDKLLYAVYRKLGVYEVEDQITAVRKFIEMGFIDEKRIAIWGWSYGGYVSSLALASGT 638 +G A+Y K G EV+DQ+ + F+D RI ++GWS GGY++ + LA Sbjct: 568 RRGAAFGGALYGKQGTVEVDDQLRGIEWLKSQAFVDPARIGVYGWSNGGYMTLMLLAKHD 627 Query: 639 GLFKCGIAVAPVSSWEYYASVYTERFMGLPTKDDNLEHYKNSTVMARAEYFRNVDYLLIH 698 + CG+A APV+ W Y + YTER+M LP N Y+ ++V + LLIH Sbjct: 628 EAYACGVAGAPVTDWALYDTHYTERYMDLPKA--NEAGYREASVFTHVDGIGAGKLLLIH 685 Query: 699 GTADDNVHFQNSAQIAKALVNAQVDFQAMWYSDQNHGLSGLSTNHLYTHMTHFLKQCF 756 G ADDNV F NS ++ L F+ M Y HGL G H Y F +C Sbjct: 686 GMADDNVLFTNSTKLMSELQKRGTPFELMTYPGAKHGLRGSDLLHRYRLTEDFFARCL 743 >2EEP-A nrPDB Length = 706 Score = 166 bits (421), Expect = 3e-41, Method: Compositional matrix adjust. Identities = 180/740 (24%), Positives = 316/740 (42%), Gaps = 84/740 (11%) Query: 47 ILNGTFSYKTFFPNWISGQEYLHQS---ADNNIVLYNIETGQSYTILSNRTMKSVNASNY 103 ++ G + F+P ++ G +++ + + + +++N G+S +T + A Sbjct: 13 LMPGGKEFYNFYPEYVVGLQWMGDNYVFIEGDDLVFNKANGKS-----AQTTRFSAADLN 67 Query: 104 GLSPDRQFVYLESDYSKLWRYSYTATYYIYDLSNGEFVRGNELPRPIQYLC--------- 154 L P+ + +D +R + + G V + L R + YL Sbjct: 68 ALMPE-GCKFQTTDAFPSFRTLDAGRGLVVLFTQGGLVGFDMLARKVTYLFDTNEETASL 126 Query: 155 -WSPVGSKLAYVYQNNIYLKQ--RPGDP---PFQITFNGRENKIFNGIPDWVYEEEMLAT 208 +SPVG ++AYV +N+Y+ + + G+ +T +G E ++ V++ E Sbjct: 127 DFSPVGDRVAYVRNHNLYIARGGKLGEGMSRAIAVTIDGTETLVYG---QAVHQREFGIE 183 Query: 209 KYALWWSPNGKFLAYAEFNDTDI---PVIAYSYYGDEQYPRTINIPYPKAG--AKNPVVR 263 K +WSP G LA+ + + + P++ Y E P + YP AG + + V Sbjct: 184 K-GTFWSPKGSCLAFYRMDQSMVKPTPIVDYHPLEAESKP----LYYPMAGTPSHHVTVG 238 Query: 264 IFIIDTTYPAYVGPQEVPVPAMIASSDYYFSWLTWVTDERVC-LQWLKRVQNVSVLSICD 322 I+ + T Y+ E + + + L+W DE + + + R QN ++ D Sbjct: 239 IYHLATGKTVYLQTGE--------PKEKFLTNLSWSPDENILYVAEVNRAQNECKVNAYD 290 Query: 323 FREDW--QTWDCPKTQEHIEESRTGWAGGFFVSTPVFSYDAISYYKIFSDKDGYKHIHYI 380 +T + ++E + F + + + S +DG+ H+ Y+ Sbjct: 291 AETGRFVRTLFVETDKHYVEP----------LHPLTFLPGSNNQFIWQSRRDGWNHL-YL 339 Query: 381 KDTVENAI-QITSGKWEAINI--FRVTQDSLFYSSNEFEEYPGRRNIYRISIGSYPPSKK 437 DT I Q+T G+WE N F L++ S E P R+ Y I I K Sbjct: 340 YDTTGRLIRQVTKGEWEVTNFAGFDPKGTRLYFESTEAS--PLERHFYCIDI------KG 391 Query: 438 CVTCHLRKERCQYYTASFSDYAKYYALVCYGPGIP--ISTLHDGRTDQEIKILEENKELE 495 T L E + T D + + P +P ++ + G+ L E K + Sbjct: 392 GKTKDLTPESGMHRTQLSPDGSAIID-IFQSPTVPRKVTVTNIGKGSH---TLLEAKNPD 447 Query: 496 NALKNIQLPKEEIKKLEVDEITLWYKMILPPQFDRSKKYPLLIQVYGGPCSQSVRSVF-- 553 ++ I + + L+YK+ +P FD +KKYP+++ VYGGP +Q V + Sbjct: 448 TGYAMPEIRTGTIMAAD-GQTPLYYKLTMPLHFDPAKKYPVIVYVYGGPHAQLVTKTWRS 506 Query: 554 -AVNWISYLASKEGMVIALVDGRGTAFQGDKLLYAVYRKLGVYEVEDQITAVRKFIEMGF 612 W Y+A K G + VD RG+A +G ++R+LG E+ DQ+ V + Sbjct: 507 SVGGWDIYMAQK-GYAVFTVDSRGSANRGAAFEQVIHRRLGQTEMADQMCGVDFLKSQSW 565 Query: 613 IDEKRIAIWGWSYGGYVSSLALASGTGLFKCGIAVAPVSSWEYYASVYTERFMGLPTKDD 672 +D RI + GWSYGG++++ + + +FK G+A PV W Y +Y ER+ P + Sbjct: 566 VDADRIGVHGWSYGGFMTTNLMLTHGDVFKVGVAGGPVIDWNRYEIMYGERYFDAP--QE 623 Query: 673 NLEHYKNSTVMARAEYFRNVDYLLIHGTADDNVHFQNSAQIAKALVNAQVDFQAMWYSDQ 732 N E Y + ++ RA + +LIHG D V +Q+S A V A+ Y Sbjct: 624 NPEGYDAANLLKRAGDLKG-RLMLIHGAIDPVVVWQHSLLFLDACVKARTYPDYYVYPSH 682 Query: 733 NHGLSGLSTNHLYTHMTHFL 752 H + G HLY +T + Sbjct: 683 EHNVMGPDRVHLYETITRYF 702 >4Q1V-A nrPDB Length = 710 Score = 151 bits (381), Expect = 1e-36, Method: Compositional matrix adjust. Identities = 156/666 (23%), Positives = 276/666 (41%), Gaps = 84/666 (12%) Query: 124 YSYTATYYIYDLSNGEFVRGNELPRPIQYLCWSPVGSKLAYVYQNNIYLKQRPGDPPFQI 183 ++ + +Y+ N + V + + +AY NN+Y+ ++ Sbjct: 92 FTIAGKFIVYNFKNNQVVSTFKPKDGANNEDYCAASGNVAYTIDNNLYVNEK-------- 143 Query: 184 TFNGRENKIFNGIPDWVYEEEMLATKYALWWSPNGKFLAYAEFND---TDIPVIAYSYYG 240 I G V+ E K +WSP G LA+ ++ T P++ + Sbjct: 144 AVTNEPEGIVCG--QTVHRNEFGINK-GTFWSPKGNLLAFYRMDESMVTQYPLVDIT--- 197 Query: 241 DEQYPRTINIPYPKAGAKNPVVRIFIID--TTYPAYVGPQEVPVPAMIASSDYYFSWLTW 298 + N+ YP AG + V++ I + T Y+ + +D YF+ ++W Sbjct: 198 -ARVGEVNNVRYPMAGMTSHQVKVGIYNPATGKSIYLNAGD--------PTDRYFTNISW 248 Query: 299 VTDER-VCLQWLKRVQNVSVLSICDFR-EDWQTWDCPKTQEHIEESRTGWAGGFFVSTPV 356 DE+ + L + R QN + L C + E + + H + F P Sbjct: 249 APDEKSLYLIEVNRDQNHAKL--CQYNAETGEPMGVLYEEMHPKYVEPQNPIVFLPWDPT 306 Query: 357 -FSYDAISYYKIFSDKDGYKHIHYIKDTVEN-------------------AIQITSGKWE 396 F Y S +DGY H++ + N Q+T G W Sbjct: 307 KFIYQ--------SQRDGYNHLYLFETNAANMKGETYNSANGGSYFQAGKVKQLTKGNWL 358 Query: 397 AINI--FRVTQDSLFYSSNEFEEYPGRRNIYRISIGSYPPSKKCVTCHLRKERCQYYTAS 454 I F + + +++ E R + +++ + S+ C + ++ + Sbjct: 359 VSEILGFNTKRKEVIFTAVEGL----RSGHFAVNVSNGKISQPFENC-----KESEHSGT 409 Query: 455 FSDYAKYYALVCYGPGIP-ISTLHDGRTDQEIKILEENKELENALKNIQLPKEEIKKLEV 513 S Y P + L D + +E L EN Q+P E ++ Sbjct: 410 LSASGTYLIDRYSTKDQPRVINLVDTKNFKETANL---LTAENPYDGYQMPSIETGTIKA 466 Query: 514 DEIT--LWYKMILPPQFDRSKKYPLLIQVYGGPCSQSVRSVF---AVNWISYLASKEGMV 568 + T L Y+++ P FD +KKYP+++ VYGGP +Q V + A W +Y+ASK G + Sbjct: 467 ADGTTDLHYRLMKPANFDPAKKYPVIVYVYGGPHAQCVTGGWQNGARGWDTYMASK-GYI 525 Query: 569 IALVDGRGTAFQGDKLLYAVYRKLGVYEVEDQITAVRKFIEMGFIDEKRIAIWGWSYGGY 628 + +D RG++ +G A +R+LG+ E +DQ+ V + ++D +RI + GWS+GG+ Sbjct: 526 MFTIDNRGSSNRGLTFENATFRRLGIEEGKDQVKGVEFLKSLPYVDSERIGVHGWSFGGH 585 Query: 629 VSSLALASGTGLFKCGIAVAPVSSWEYYASVYTERFMGLPTKDDNLEHYKNSTVMARAEY 688 +++ + +FK G+A PV W YY +Y ER+M P + N E YK + A+ Sbjct: 586 MTTALMLRYPEIFKVGVAGGPVIDWGYYEIMYGERYMDTP--ESNPEGYKECNLKNLADQ 643 Query: 689 FRNVDYLLIHGTADDNVHFQNSAQIAKALVNAQVDFQAMWYSDQNHGLSGLSTNHLYTHM 748 + L+IH DD Q++ KA V+A+ Y H ++G HL+ + Sbjct: 644 LKG-HLLIIHDDHDDTCVPQHTLSFMKACVDARTYPDLFIYPCHKHNVAGRDRVHLHEKI 702 Query: 749 THFLKQ 754 T + +Q Sbjct: 703 TRYFEQ 708 >6EOT-A nrPDB Length = 898 Score = 142 bits (357), Expect = 7e-34, Method: Compositional matrix adjust. Identities = 170/677 (25%), Positives = 287/677 (42%), Gaps = 102/677 (15%) Query: 162 LAYVYQNNIYLKQRPGDPPFQITF------NGRENKIFNGIPDWVYEEEMLATKYA-LWW 214 +A+++ N+I++ ++T+ N E+ G+ +V +EE +Y+ WW Sbjct: 228 IAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEEF--DRYSGYWW 285 Query: 215 SPN-------GKFLA--YAEFNDTDIPVIAYSYYGDEQYPRTINIPYPKAGAKNPVVRI- 264 P GK L Y E +++++ +I + E R + YPK G NP V Sbjct: 286 CPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETR-RADSFRYPKTGTANPKVTFK 344 Query: 265 ----------FIIDTTYPAYVGPQEVPVPAM--IASSDYY----FSWLTWVTDERVCLQW 308 IID + P E+ + IA + + ++W + + LQ Sbjct: 345 MSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQI 404 Query: 309 LKRVQNVSVLSICDFREDWQTWD-CPKTQEHI---EESRTGWAG--GFFVSTPVFSYDAI 362 + + + D E + + P + + EE+ W F P + I Sbjct: 405 VLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEI 464 Query: 363 SYYKIFSDKDGYKHIHYI----------------------KDTVENAIQITSGKWEAI-- 398 + K G++H++ I K ++ I ITSG+WE + Sbjct: 465 EFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGR 524 Query: 399 ---NI----------FRVTQDSLFYSSNEFEEYPGRRNIYRISIGSYPPSKKCVTCHLRK 445 NI F T+DS Y + R++ Y S C++ H Sbjct: 525 HGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSC-CISQH--- 580 Query: 446 ERCQYYTASFSDYAKYYALVCYGPGIPISTLHDGRTDQEIKILEENKELENALKNIQLPK 505 C ++ + +S+ + + Y +S+ D T + + + L + P Sbjct: 581 --CDFFISKYSNQKNPHCVSLYK----LSSPEDDPTCKTKEFWATILDSAGPLPDYTPP- 633 Query: 506 EEIKKLE-VDEITLWYKMILPPQFDRSKKYPLLIQVYGGPCSQSVRSVF-AVNW--ISYL 561 EI E TL+ + P KKYP ++ +YGGP Q V + F V + ++ L Sbjct: 634 -EIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTL 692 Query: 562 ASKEGMVIALVDGRGTAFQGDKLLYAVYRKLGVYEVEDQITAVRKFIEM-GFIDEKRIAI 620 AS G V+ ++D RG+ +G K A K+G E++DQ+ ++ FID R+ I Sbjct: 693 ASL-GYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGI 751 Query: 621 WGWSYGGYVSSLALASGTGLFKCGIAVAPVSSWEYYASVYTERFMGLPTKDDNLEHYKNS 680 GWSYGGY+S +AL + +F+ IA APV+ W +Y + YTER+MG P D N + Y Sbjct: 752 HGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMGHP--DQNEQGYYLG 809 Query: 681 TVMARAEYFRNV--DYLLIHGTADDNVHFQNSAQIAKALVNAQVDFQAMWYSDQNHGLS- 737 +V +AE F + LL+HG D+NVHF +++ + LV A + Y + H + Sbjct: 810 SVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRV 869 Query: 738 GLSTNHLYTHMTHFLKQ 754 S H H+ H+L++ Sbjct: 870 PESGEHYELHLLHYLQE 886 >6EOR-A nrPDB Length = 869 Score = 134 bits (336), Expect = 2e-31, Method: Compositional matrix adjust. Identities = 109/393 (27%), Positives = 183/393 (46%), Gaps = 28/393 (7%) Query: 380 IKDTVENAIQITSGKWEAI-----NIFRVTQDSLFYSSNEFEEYPGRRNIYRISIGSYPP 434 K ++ I +TSG+WE + I+ + L Y ++ P ++Y +S + Sbjct: 479 FKCPIKEEIALTSGEWEVLARHGSKIWVNEETKLVYFQGT-KDTPLEHHLYVVSYEAAGE 537 Query: 435 SKKCVTCHLRKERCQYYTASFSDYAKYYALVCYGPGIPISTLHDGRTDQEIKILEENKEL 494 + T C + +F + +Y+ V P + + L G D + ++ + Sbjct: 538 IVRLTTPGF-SHSCSM-SQNFDMFVSHYSSVSTPPCVHVYKL-SGPDDDPLH--KQPRFW 592 Query: 495 ENALKNIQLPKE----EIKKLEVDEITLWYKMILPPQ-FDRSKKYPLLIQVYGGPCSQSV 549 + ++ P + EI Y MI P KK+P ++ VYGGP Q V Sbjct: 593 ASMMEAASCPPDYVPPEIFHFHTRSDVRLYGMIYKPHALQPGKKHPTVLFVYGGPQVQLV 652 Query: 550 RSVFAVNWISYLA----SKEGMVIALVDGRGTAFQGDKLLYAVYRKLGVYEVEDQITAVR 605 + F I YL + G + ++DGRG+ +G + A+ ++G E+EDQ+ ++ Sbjct: 653 NNSF--KGIKYLRLNTLASLGYAVVVIDGRGSCQRGLRFEGALKNQMGQVEIEDQVEGLQ 710 Query: 606 KFIEM-GFIDEKRIAIWGWSYGGYVSSLALASGTGLFKCGIAVAPVSSWEYYASVYTERF 664 E GFID R+AI GWSYGG++S + L +FK IA APV+ W Y + YTER+ Sbjct: 711 FVAEKYGFIDLSRVAIHGWSYGGFLSLMGLIHKPQVFKVAIAGAPVTVWMAYDTGYTERY 770 Query: 665 MGLPTKDDNLEHYKNSTVMARAEYFRNVD--YLLIHGTADDNVHFQNSAQIAKALVNAQV 722 M +P ++N Y+ +V E N L++HG D+NVHF ++ + L+ A Sbjct: 771 MDVP--ENNQHGYEAGSVALHVEKLPNEPNRLLILHGFLDENVHFFHTNFLVSQLIRAGK 828 Query: 723 DFQAMWYSDQNHGL-SGLSTNHLYTHMTHFLKQ 754 +Q Y ++ H + S H + HFL++ Sbjct: 829 PYQLQIYPNERHSIRCPESGEHYEVTLLHFLQE 861 >4HXF-B nrPDB Length = 622 Score = 59.7 bits (143), Expect = 4e-09, Method: Compositional matrix adjust. Identities = 55/195 (28%), Positives = 93/195 (47%), Gaps = 17/195 (8%) Query: 515 EITLWYKMILPPQFDRSKKYPLLIQVYGGPCSQSVRSVFAVNWISYLASKEGMVIALVDG 574 E+ WY + P+ +K P+++ V+GGP + + + + +ASK G I V+ Sbjct: 362 ELDGWY---IKPEIKEGEKAPVIVFVHGGP--KGMYGYYFKYEMQLMASK-GYYIVYVNP 415 Query: 575 RGTAFQGDKLLYAVYRKLGVYEVEDQITAVRKFIEMG-FIDEKRIAIWGWSYGGYVSSLA 633 RG+ + V + G+ + +D + + +F+ + D +RI I G SYGGY+++ A Sbjct: 416 RGSNGYSEDFALRVLERTGLEDFQDILNGIEEFLRLEPQADRERIGITGISYGGYMTNWA 475 Query: 634 LASGTGLFKCGIAVAPVSSWEYYASVYTERFMGL----PTKDDNLEHYKNSTVMARAEYF 689 L + LFK GI+ +S W + Y +GL DN +N ++ Y Sbjct: 476 LTQ-SDLFKAGISENGISYW---LTSYAFSDIGLWFDKEVIGDNPLENENYRKLSPLFYA 531 Query: 690 RNVD--YLLIHGTAD 702 +NV LLIH D Sbjct: 532 KNVKAPLLLIHSLED 546 >5L8S-A nrPDB Length = 604 Score = 54.3 bits (129), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 57/226 (25%), Positives = 92/226 (40%), Gaps = 14/226 (6%) Query: 541 YGGPCSQSVRSVFAVNWISYLASKEGMVIALVDGRGTAFQGDKLLYAVYRKLGVYEVEDQ 600 +GGP S R +F + ++ G I + RG+ G V G D Sbjct: 378 HGGPQSAE-RKMFRSMFQCFI--NRGYTIFAPNFRGSTGYGSAFTKLVELDWGEGPRLDC 434 Query: 601 ITAVRKFIEMGFIDEKRIAIWGWSYGGYVSSLALASGTGLFKCGIAV-APVSSWEYYASV 659 I + E GF D ++ + G SYGGY++ L + F+ + + P + + SV Sbjct: 435 IAGIEWLFESGFTDRNKLFLVGGSYGGYMALLLHGRHSDYFRAVVDIFGPSDLFTFINSV 494 Query: 660 ------YTERFMGLPTKDDNLEHYKNSTVMARAEYFRNVDYLLIHGTADDNVHFQNSAQI 713 ER++G P +D K+S V + + L+I G D V + S QI Sbjct: 495 PPHWKPIMERWLGDPERDKE-RFIKDSPVTYLDGMVKPM--LVIQGAKDPRVVKEESDQI 551 Query: 714 AKALVNAQVDFQAMWYSDQNHGLSGLSTN-HLYTHMTHFLKQCFSL 758 L D + + D+ HG S +Y+ M FL++ +L Sbjct: 552 VAKLKEKGRDVEYLVLEDEGHGFSKKENEIKVYSLMLAFLEKHQAL 597 >3O4I-A nrPDB Length = 582 Score = 51.6 bits (122), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 40/122 (32%), Positives = 60/122 (49%), Gaps = 9/122 (7%) Query: 535 PLLIQVYGGPCSQSVRSVFAVNWISYLAS--KEGMVIALVDGRGTAFQGDKLLYAVYRKL 592 P ++ V+GGP ++ S W ++ AS G + + + RG+ G++ + Sbjct: 361 PTVVLVHGGPFAEDSDS-----WDTFAASLAAAGFHVVMPNYRGSTGYGEEWRLKIIGDP 415 Query: 593 GVYEVEDQITAVRKFIEMGFIDEKRIAIWGWSYGGYVSSLALASGTGLFKCGIAVAPVSS 652 E+ED A R E G E + I G+SYGGY++ AL GLFK G+A A V Sbjct: 416 CGGELEDVSAAARWARESGLASE--LYIMGYSYGGYMTLCALTMKPGLFKAGVAGASVVD 473 Query: 653 WE 654 WE Sbjct: 474 WE 475 >3AZQ-A nrPDB Length = 662 Score = 48.5 bits (114), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 51/208 (24%), Positives = 96/208 (46%), Gaps = 11/208 (5%) Query: 535 PLLIQVYGGPCSQSVRSVFAVNWISYLASKEGMVIALVDGRGTAFQGDKLLYAVYRKLGV 594 P ++ +GGP S+ V +V ++ ++Y S+ G+ +A V+ G+ G + + GV Sbjct: 425 PYVVMAHGGPTSR-VPAVLDLD-VAYFTSR-GIGVADVNYGGSTGYGRAYRERLRGRWGV 481 Query: 595 YEVEDQITAVRKFIEMGFIDEKRIAIWGWSYGGYVSSLALASGTGLFKCGIAVAPVSSWE 654 +VED E G D R+A+ G + GG+ ++ +L S T ++ CG + PV Sbjct: 482 VDVEDCAAVATALAEEGTADRARLAVRGGAAGGWTAASSLVS-TDVYACGTVLYPVLDLL 540 Query: 655 YYASVYTERFMG------LPTKDDNLEHYKNSTVMARAEYFRNVDYLLIHGTADDNVHFQ 708 +A T F + + ++ E Y++ + RA+ R V +LL+ G D + Sbjct: 541 GWADGGTHDFESRYLDFLIGSFEEFPERYRDRAPLTRADRVR-VPFLLLQGLEDPVCPPE 599 Query: 709 NSAQIAKALVNAQVDFQAMWYSDQNHGL 736 + +A+ V + + + HG Sbjct: 600 QCDRFLEAVAGCGVPHAYLSFEGEGHGF 627 >6IGR-A nrPDB Length = 656 Score = 44.3 bits (103), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 52/247 (21%), Positives = 110/247 (44%), Gaps = 22/247 (8%) Query: 501 IQLPKEEIKKLEVDEITLWYKMILPPQFDRSKKYPLLIQVYGGPCSQSVRSVFAVNWISY 560 ++ P+ + E+ E W ++LP + +K P L+ ++GGP + + Sbjct: 399 VREPQRVTFETELGEGEGW--VLLP---EGEQKVPALLNIHGGPHTDYGHGF--THEFQL 451 Query: 561 LASKEGMVIALVDGRGTAFQGDKLLYAVYRKLGVYEVEDQITAVRKFIE-MGFIDEKRIA 619 +A++ G + + RG+ G + A+Y + G + +D + + +E + +D + A Sbjct: 452 MAAR-GYGVCYSNPRGSVGYGQAWVDAIYGRWGTVDADDLLNFFDRCLEAVPRLDAAKTA 510 Query: 620 IWGWSYGGYVSSLALASGTGLFKCGIAVAPVSSWEYYASVYTERFMGLPTKDD--NLEHY 677 + G +YGG++++ + T F+ I +S+ + +GL DD L+ Sbjct: 511 VMGGAYGGFMTNW-ITGHTTRFQAAITDRCISNLISFGGTSD---IGLRFWDDELGLDFS 566 Query: 678 KNSTVM-----ARAEYFRNVDY--LLIHGTADDNVHFQNSAQIAKALVNAQVDFQAMWYS 730 + + + + +Y NV L++H D + + Q AL QV + + + Sbjct: 567 RRADALKLWDLSPLQYVENVKTPTLIVHSVLDHRCPVEQAEQWYAALHKHQVPVRFVRFP 626 Query: 731 DQNHGLS 737 ++NH LS Sbjct: 627 EENHELS 633 >5UW6-A nrPDB Length = 750 Score = 43.5 bits (101), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 39/168 (23%), Positives = 66/168 (39%), Gaps = 16/168 (9%) Query: 493 ELENALKNIQLPKEEIKKLEVDEITLWYKMILPPQFDRSKKYPLLIQVYGG-------PC 545 +L+N +++ +E + + D K + P D +K P+ I G PC Sbjct: 445 DLKNDPTQLKIFRESVVP-DFDRSEFEVKQVFVPSKDGTK-IPIFIAARKGISLDGSHPC 502 Query: 546 SQSVRSVFAVNWISYLASKE-------GMVIALVDGRGTAFQGDKLLYAVYRKLGVYEVE 598 F +N + ++ G V L + RG G++ A +R + Sbjct: 503 EMHGYGGFGINMMPTFSASRIVFLKHLGGVFCLANIRGGGEYGEEWHKAGFRDKKQNVFD 562 Query: 599 DQITAVRKFIEMGFIDEKRIAIWGWSYGGYVSSLALASGTGLFKCGIA 646 D I+A I G+ +R+AI G S GG + + + LF C A Sbjct: 563 DFISAAEYLISSGYTKARRVAIEGGSNGGLLVAACINQRPDLFGCAEA 610 >3WYD-A nrPDB Length = 228 Score = 37.4 bits (85), Expect = 0.028, Method: Composition-based stats. Identities = 31/110 (28%), Positives = 49/110 (44%), Gaps = 12/110 (10%) Query: 520 YKMILPPQFDRSKKYPLLIQVYG-GPCSQSVRSVFAVNWISYLASKEGMVIALVDGRGTA 578 Y++ +P +D +K +PL+I ++G G S + A G ++A GR A Sbjct: 23 YRLYVPTTYDGTKAFPLVIALHGMGGDENSYFDSYQRGAFMIEAENRGYIVACPKGRQPA 82 Query: 579 FQGDKLLYAVYRKLGVYEVEDQITAVRKFIEMGFIDEKRIAIWGWSYGGY 628 ++Y +V D I VR+ + ID RI + G S GGY Sbjct: 83 --------SMYVGPAERDVMDVIAEVRRDYK---IDPDRIYMTGHSMGGY 121 >4WY5-A nrPDB Length = 332 Score = 36.6 bits (83), Expect = 0.039, Method: Compositional matrix adjust. Identities = 29/88 (32%), Positives = 46/88 (52%), Gaps = 12/88 (13%) Query: 458 YAKYYALVCYGPGIPISTLHDGRTDQEIKILEENKELENALKNIQLPK--EEIKKLEVDE 515 YA +A + P PI TL ++K++ E+ E NI+LP+ EE K +E D Sbjct: 12 YAAAFAAMKERP--PIHTL-------DLKVVRESSEARQLAANIKLPEVIEEDKVVESDG 62 Query: 516 ITLWYKMILPPQFDRSKKYPLLIQVYGG 543 TL ++ PP + + P+LI ++GG Sbjct: 63 KTLKLTIVRPPGTE-DQILPVLIFLHGG 89 >3FCX-A nrPDB Length = 282 Score = 33.1 bits (74), Expect = 0.49, Method: Compositional matrix adjust. Identities = 40/164 (24%), Positives = 70/164 (42%), Gaps = 23/164 (14%) Query: 509 KKLEVDEITLWYKM----ILPPQFDRSKKYPLLIQVYGGPCSQSVRSVFAVNWISYLASK 564 K E D + L KM LPP+ + + K P L + G C++ ++ + + AS+ Sbjct: 17 KVFEHDSVELNCKMKFAVYLPPKAE-TGKCPALYWLSGLTCTE--QNFISKSGYHQSASE 73 Query: 565 EGMVIALVDG--RGTAFQGDKLLYAVYRKLGVY--EVEDQ-----------ITAVRKFIE 609 G+V+ D RG +G+ + G Y ED + + I Sbjct: 74 HGLVVIAPDTSPRGCNIKGEDESWDFGTGAGFYVDATEDPWKTNYRMYSYVTEELPQLIN 133 Query: 610 MGF-IDEKRIAIWGWSYGGYVSSLALASGTGLFKCGIAVAPVSS 652 F +D +R++I+G S GG+ + + G +K A AP+ + Sbjct: 134 ANFPVDPQRMSIFGHSMGGHGALICALKNPGKYKSVSAFAPICN 177 >3DYV-A nrPDB Length = 251 Score = 32.3 bits (72), Expect = 0.87, Method: Compositional matrix adjust. Identities = 37/158 (23%), Positives = 71/158 (44%), Gaps = 24/158 (15%) Query: 617 RIAIWGWSYGGYVSSLALASGTGLFKCGIAVAPVSSWEYYA-------SVYTERFMG--- 666 ++ ++G S GG + AL + G+ G+ +P+ +++ + Y R G Sbjct: 94 KVFVFGLSLGGIFAMKALETLPGITAGGVFSSPILPGKHHLVPGFLKYAEYMNRLAGKSD 153 Query: 667 --------LPTKDDNLEHYKNSTVMARAEYFRNVDYLLIHGTADDNVHFQNSAQIAKALV 718 LP + ++ + +TV A + ++ G D+ V + + Q+ AL+ Sbjct: 154 ESTQILAYLPGQLAAIDQFA-TTVAADLNLVKQPTFIGQAGQ-DELVDGRLAYQLRDALI 211 Query: 719 N-AQVDFQAMWYSDQNHGLSGLSTNH-LYTHMTHFLKQ 754 N A+VDF WY D H ++ S +H L + F++Q Sbjct: 212 NAARVDFH--WYDDAKHVITVNSAHHALEEDVIAFMQQ 247 >2XE4-A nrPDB Length = 751 Score = 30.4 bits (67), Expect = 2.7, Method: Compositional matrix adjust. Identities = 33/141 (23%), Positives = 53/141 (37%), Gaps = 12/141 (8%) Query: 514 DEITLWYKMILPPQFDRSKKYPLLIQVYGGPCSQSVRSVFAVNWISYLASKEGMVIALVD 573 D+ + ++ D S+ P ++ YG S+ F++ + Y GM+ A+ Sbjct: 489 DQTKIPLSVVYHKDLDMSQPQPCMLYGYGS-YGLSMDPQFSIQHLPYC--DRGMIFAIAH 545 Query: 574 GRGTAFQGDKLLYAVYRKLGVYEVE-----DQITAVRKFIEMGFIDEKRIAIWGWSYGGY 628 RG G +L A Y Y + D I A + ++A G S GG Sbjct: 546 IRG----GSELGRAWYEIGAKYLTKRNTFSDFIAAAEFLVNAKLTTPSQLACEGRSAGGL 601 Query: 629 VSSLALASGTGLFKCGIAVAP 649 + L LFK +A P Sbjct: 602 LMGAVLNMRPDLFKVALAGVP 622 >3KSR-A nrPDB Length = 290 Score = 30.4 bits (67), Expect = 3.3, Method: Compositional matrix adjust. Identities = 13/36 (36%), Positives = 22/36 (61%) Query: 597 VEDQITAVRKFIEMGFIDEKRIAIWGWSYGGYVSSL 632 ++D A + + ++D IA+ G SYGGY+S+L Sbjct: 82 LDDIKAAYDQLASLPYVDAHSIAVVGLSYGGYLSAL 117 >4AMY-A nrPDB Length = 710 Score = 30.4 bits (67), Expect = 3.3, Method: Compositional matrix adjust. Identities = 31/122 (25%), Positives = 53/122 (43%), Gaps = 12/122 (9%) Query: 534 YPLLIQVYGGPCSQSVRSVFAVNWISYLASKEGMVIALVDGRGTAFQGDKLLYAVYRKLG 593 +P + YGG + S+ ++V+ + ++ G V+A+ + RG G+ + K G Sbjct: 466 HPAFLYGYGG-FNISITPNYSVSRLIFVRHMGG-VLAVANIRGGGEYGE-----TWHKGG 518 Query: 594 VYE-----VEDQITAVRKFIEMGFIDEKRIAIWGWSYGGYVSSLALASGTGLFKCGIAVA 648 + +D A I+ G+ KR+ I G S GG + + LF C IA Sbjct: 519 ILANKQNCFDDFQCAAEYLIKEGYTSPKRLTINGGSNGGLLVATCANQRPDLFGCVIAQV 578 Query: 649 PV 650 V Sbjct: 579 GV 580 >1C5K-A nrPDB Length = 439 Score = 30.0 bits (66), Expect = 3.5, Method: Compositional matrix adjust. Identities = 12/19 (63%), Positives = 14/19 (73%) Query: 147 PRPIQYLCWSPVGSKLAYV 165 P+P+ WSP GSKLAYV Sbjct: 200 PQPLMSPAWSPDGSKLAYV 218 >5XZO-A nrPDB Length = 335 Score = 30.0 bits (66), Expect = 4.1, Method: Compositional matrix adjust. Identities = 12/25 (48%), Positives = 17/25 (68%) Query: 733 NHGLSGLSTNHLYTHMTHFLKQCFS 757 N LS + NH+YT ++HF QC+S Sbjct: 105 NETLSKVLQNHVYTLVSHFGDQCYS 129 >5T88-A nrPDB Length = 616 Score = 29.3 bits (64), Expect = 6.2, Method: Compositional matrix adjust. Identities = 41/173 (23%), Positives = 70/173 (40%), Gaps = 16/173 (9%) Query: 541 YGGPCSQSVRSVFAVNWISYLASKEGMVIALVDGRGTAFQGDKLLYAVYRKLGVYEVEDQ 600 YGG + ++ +F I +L K G + + RG + G++ A R+ +D Sbjct: 401 YGG-FNIALTPMFFPQVIPFL--KRGGTFIMANLRGGSEYGEEWHRAGMRENKQNVFDDF 457 Query: 601 ITAVRKFIEMGFIDEKRIAIWGWSYGGYVSSLALASGTGLFKCGIAVAPVSSWEYYASVY 660 I + K + G+ ++A WG S GG + S L + + PV + +Y Sbjct: 458 IAVLEKLKKEGY----KVAAWGRSNGGLLVSATLTQRPDVMDSALIGYPVIDMLRFHKLY 513 Query: 661 TERFMGLPTKDDNLEHYKNSTVMARAEYFRNVD-------YLLIHGTADDNVH 706 + +P N E K+ + + + NVD L+ G DD VH Sbjct: 514 IGS-VWIPEY-GNPEDPKDREFLLKYSPYHNVDPKKKYPPTLIYTGLHDDRVH 564 >5IYD-S nrPDB Length = 517 Score = 29.3 bits (64), Expect = 6.3, Method: Compositional matrix adjust. Identities = 29/98 (29%), Positives = 42/98 (42%), Gaps = 9/98 (9%) Query: 134 DLSNGEFVRGNELPRPIQYLCWSPVGSKL---AYVYQNNIYLKQ-RPGDPPFQITFNGRE 189 DLSN + + E+P + S KL A + I LK+ RP D P+ + NG+ Sbjct: 50 DLSNKKIYQEEEMP---ESGAGSEFNRKLREEARRKKYGIVLKEFRPEDQPWLLRVNGKS 106 Query: 190 NKIFNGIPDWVYEEEMLATKYALWWSPNGKFLAYAEFN 227 + F GI E + Y P+G F A+ N Sbjct: 107 GRKFKGIKKGGVTEN--TSYYIFTQCPDGAFEAFPVHN 142 >4F7W-A nrPDB Length = 334 Score = 29.3 bits (64), Expect = 7.0, Method: Compositional matrix adjust. Identities = 14/41 (34%), Positives = 23/41 (56%), Gaps = 1/41 (2%) Query: 368 FSDKDGYKHIHYIKDTVENAIQITSGKWEAINIFRVTQDSL 408 F+D D Y H +Y K + E A+ I + W IN+ + ++ L Sbjct: 270 FTDPDSYFH-NYAKLSKEEAVDIATSLWNEINLMNLKENIL 309 >1GME-A nrPDB Length = 151 Score = 29.3 bits (64), Expect = 7.1, Method: Composition-based stats. Identities = 14/39 (35%), Positives = 22/39 (56%) Query: 480 RTDQEIKILEENKELENALKNIQLPKEEIKKLEVDEITL 518 R ++ K+ E LEN + + +PK E+KK EV I + Sbjct: 111 RLLEDAKVEEVKAGLENGVLTVTVPKAEVKKPEVKAIQI 149 >6C26-A nrPDB Length = 718 Score = 28.9 bits (63), Expect = 9.5, Method: Compositional matrix adjust. Identities = 12/30 (40%), Positives = 17/30 (56%) Query: 208 TKYALWWSPNGKFLAYAEFNDTDIPVIAYS 237 T + +W P G FL + + D + VIAYS Sbjct: 363 THFLIWLFPAGVFLLFLDLKDEHVFVIAYS 392 >2BKL-A nrPDB Length = 695 Score = 28.9 bits (63), Expect = 9.8, Method: Compositional matrix adjust. Identities = 30/125 (24%), Positives = 55/125 (44%), Gaps = 7/125 (5%) Query: 528 FDRSKKYPLLIQVYGGPCSQSVRSVFAVNWISYLASKEGMVIALVDGRGTAFQGDKLLYA 587 R P L+ YGG + ++ + F + + +L + G V A+ + RG G A Sbjct: 440 LKRDGNAPTLLYGYGG-FNVNMEANFRSSILPWLDA--GGVYAVANLRGGGEYGKAWHDA 496 Query: 588 --VYRKLGVYEVEDQITAVRKFIEMGFIDEKRIAIWGWSYGGYVSSLALASGTGLFKCGI 645 + +K V++ D A ++ + KR+AI+G S GG + A+ L+ + Sbjct: 497 GRLDKKQNVFD--DFHAAAEYLVQQKYTQPKRLAIYGGSNGGLLVGAAMTQRPELYGAVV 554 Query: 646 AVAPV 650 P+ Sbjct: 555 CAVPL 559 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 2QT9-A nrPDB 985 0.0 1Z68-A nrPDB 971 0.0 2AJB-A nrPDB 960 0.0 2GBG-A nrPDB 947 0.0 4WJL-A nrPDB 812 0.0 1XFD-A nrPDB 792 0.0 5YP1-A nrPDB 716 0.0 5OLJ-A nrPDB 700 0.0 2ECF-A nrPDB 669 0.0 2EEP-A nrPDB 629 e-180 4Q1V-A nrPDB 576 e-164 6EOT-A nrPDB 517 e-147 6EOR-A nrPDB 453 e-127 6IGR-A nrPDB 230 2e-60 5L8S-A nrPDB 223 2e-58 4HXF-B nrPDB 206 2e-53 3AZQ-A nrPDB 188 8e-48 3O4I-A nrPDB 164 2e-40 5UW6-A nrPDB 157 2e-38 Sequences not found previously or not previously below threshold: 4AMY-A nrPDB 121 2e-27 1YR2-A nrPDB 119 4e-27 2BKL-A nrPDB 119 6e-27 5T88-A nrPDB 114 1e-25 3MUN-A nrPDB 108 1e-23 4HVT-A nrPDB 101 9e-22 5N4B-A nrPDB 98 2e-20 2XE4-A nrPDB 91 2e-18 3WYD-A nrPDB 84 3e-16 4BP8-A nrPDB 83 3e-16 5TXC-A nrPDB 76 5e-14 5AOA-A nrPDB 71 1e-12 3FCY-A nrPDB 65 1e-10 5JRK-A nrPDB 63 4e-10 6FKX-A nrPDB 61 2e-09 3KSR-A nrPDB 59 6e-09 5V5V-A nrPDB 59 7e-09 3FCX-A nrPDB 55 9e-08 1C7J-A nrPDB 54 2e-07 3I6Y-A nrPDB 54 3e-07 4Q3K-A nrPDB 54 3e-07 4V2I-A nrPDB 53 4e-07 1K4Y-A nrPDB 53 5e-07 6AAE-A nrPDB 53 6e-07 5XKS-A nrPDB 52 1e-06 3RLI-A nrPDB 51 2e-06 3BIX-A nrPDB 51 2e-06 2WQZ-A nrPDB 50 3e-06 5X6S-A nrPDB 49 5e-06 6AVW-A nrPDB 49 6e-06 1MX5-A nrPDB 49 7e-06 5XB6-A nrPDB 49 8e-06 5FV4-A nrPDB 49 9e-06 3HEA-A nrPDB 48 2e-05 5HFN-A nrPDB 48 2e-05 2XLB-A nrPDB 48 2e-05 2HDW-A nrPDB 47 4e-05 1A8S-A nrPDB 46 4e-05 3HXK-A nrPDB 46 5e-05 2OCI-A nrPDB 46 5e-05 3LS2-A nrPDB 46 7e-05 4WY5-A nrPDB 45 9e-05 6GUD-A nrPDB 45 1e-04 1THG-A nrPDB 44 2e-04 2YH2-A nrPDB 43 4e-04 4B6G-A nrPDB 43 4e-04 4WY8-A nrPDB 43 6e-04 3DYV-A nrPDB 43 6e-04 1UFO-A nrPDB 43 7e-04 5FDF-A nrPDB 43 7e-04 3RAR-A nrPDB 43 8e-04 1C5K-A nrPDB 42 8e-04 4R40-A nrPDB 42 0.001 2YYS-A nrPDB 42 0.001 2O7R-A nrPDB 42 0.001 2C7B-A nrPDB 42 0.001 1ODT-C nrPDB 41 0.002 6GI5-A nrPDB 41 0.002 4DGQ-A nrPDB 41 0.002 4BZW-A nrPDB 41 0.002 5LZ5-A nrPDB 41 0.002 1LLF-A nrPDB 41 0.003 3E4D-A nrPDB 41 0.003 4PF1-A nrPDB 40 0.004 1MPX-A nrPDB 40 0.005 6AGQ-A nrPDB 40 0.005 3N0T-A nrPDB 39 0.007 5L2P-A nrPDB 39 0.008 5DWD-A nrPDB 39 0.009 2JBW-A nrPDB 39 0.010 1GZ7-A nrPDB 38 0.012 4KRY-A nrPDB 38 0.016 1R88-A nrPDB 38 0.018 3WMR-A nrPDB 38 0.019 2D81-A nrPDB 37 0.019 1NX9-A nrPDB 37 0.021 1XRN-A nrPDB 37 0.023 4IQ4-A nrPDB 37 0.029 3FNB-A nrPDB 37 0.031 2W6C-X nrPDB 36 0.044 6EMI-A nrPDB 36 0.048 3CN7-A nrPDB 36 0.056 4ZWN-A nrPDB 36 0.059 1DIN-A nrPDB 36 0.060 1BRO-A nrPDB 35 0.11 5CXX-A nrPDB 35 0.11 3HLK-A nrPDB 35 0.12 1AUO-A nrPDB 35 0.16 1LNS-A nrPDB 34 0.20 5BPT-A nrPDB 34 0.26 3FOB-A nrPDB 34 0.29 6BX3-A nrPDB 34 0.34 5BPW-A nrPDB 34 0.34 3MGA-A nrPDB 33 0.49 5TOS-A nrPDB 32 0.65 6EIC-C nrPDB 32 0.79 5JM6-A nrPDB 32 0.81 4QWW-A nrPDB 32 0.81 5W8P-A nrPDB 32 0.90 4X8E-A nrPDB 32 1.0 6QAA-A nrPDB 32 1.1 5J54-A nrPDB 32 1.1 1GQI-A nrPDB 32 1.1 2B20-A nrPDB 32 1.4 4BZF-A nrPDB 31 1.4 2IVF-A nrPDB 31 1.7 5GQY-A nrPDB 31 2.3 3WLA-A nrPDB 31 2.4 1AZW-A nrPDB 31 2.6 4NOX-A nrPDB 30 3.4 >2QT9-A nrPDB Length = 766 Score = 985 bits (2545), Expect = 0.0, Method: Composition-based stats. Identities = 390/750 (52%), Positives = 533/750 (71%), Gaps = 10/750 (1%) Query: 17 LALLVMCIVLRPSRVHNSEENTMRALTLKDILNGTFSYKTFFPNWISGQEYLHQSADNNI 76 + ++ + +VL ++ +T + TL D L T+ K + WIS EYL++ +NNI Sbjct: 18 VTIITVPVVLLNKGTDDATADTRKTYTLTDYLKNTYRLKLYSLRWISDHEYLYKQ-ENNI 76 Query: 77 VLYNIETGQSYTILSNRTMKSVNAS--NYGLSPDRQFVYLESDYSKLWRYSYTATYYIYD 134 +++N E G S L N T S +Y +SPD QF+ LE +Y K WR+SYTA+Y IYD Sbjct: 77 LVFNAEYGNSSVFLENSTFDEFGHSINDYSISPDGQFILLEYNYVKQWRHSYTASYDIYD 136 Query: 135 LSNGEFVRGNELPRPIQYLCWSPVGSKLAYVYQNNIYLKQRPGDPPFQITFNGRENKIFN 194 L+ + + +P Q++ WSPVG KLAYV+ N+IY+K P P ++IT+ G+E+ I+N Sbjct: 137 LNKRQLITEERIPNNTQWVTWSPVGHKLAYVWNNDIYVKIEPNLPSYRITWTGKEDIIYN 196 Query: 195 GIPDWVYEEEMLATKYALWWSPNGKFLAYAEFNDTDIPVIAYSYYGDE--QYPRTINIPY 252 GI DWVYEEE+ + ALWWSPNG FLAYA+FNDT++P+I YS+Y DE QYP+T+ +PY Sbjct: 197 GITDWVYEEEVFSAYSALWWSPNGTFLAYAQFNDTEVPLIEYSFYSDESLQYPKTVRVPY 256 Query: 253 PKAGAKNPVVRIFIIDTTYPAYVGPQ---EVPVPAMIASSDYYFSWLTWVTDERVCLQWL 309 PKAGA NP V+ F+++T + V ++ PA + D+Y +TW T ER+ LQWL Sbjct: 257 PKAGAVNPTVKFFVVNTDSLSSVTNATSIQITAPASMLIGDHYLCDVTWATQERISLQWL 316 Query: 310 KRVQNVSVLSICDFREDWQTWDCPKTQEHIEESRTGWAGGFFVSTPVFSYDAISYYKIFS 369 +R+QN SV+ ICD+ E W+C ++HIE S TGW G F S P F+ D S+YKI S Sbjct: 317 RRIQNYSVMDICDYDESSGRWNCLVARQHIEMSTTGWVGRFRPSEPHFTLDGNSFYKIIS 376 Query: 370 DKDGYKHIHYIKDTVENAIQITSGKWEAINIFRVTQDSLFYSSNEFEEYPGRRNIYRISI 429 +++GY+HI Y + ++ IT G WE I I +T D L+Y SNE++ PG RN+Y+I + Sbjct: 377 NEEGYRHICYFQIDKKDCTFITKGTWEVIGIEALTSDYLYYISNEYKGMPGGRNLYKIQL 436 Query: 430 GSYPPSKKCVTCHLRKERCQYYTASFSDYAKYYALVCYGPGIPISTLHDGRTDQEIKILE 489 Y C++C L ERCQYY+ SFS AKYY L C GPG+P+ TLH D+ +++LE Sbjct: 437 SDYT-KVTCLSCELNPERCQYYSVSFSKEAKYYQLRCSGPGLPLYTLHSSVNDKGLRVLE 495 Query: 490 ENKELENALKNIQLPKEEIKKLEVDEITLWYKMILPPQFDRSKKYPLLIQVYGGPCSQSV 549 +N L+ L+N+Q+P +++ + ++E WY+MILPP FD+SKKYPLL+ VY GPCSQ Sbjct: 496 DNSALDKMLQNVQMPSKKLDFIILNETKFWYQMILPPHFDKSKKYPLLLDVYAGPCSQKA 555 Query: 550 RSVFAVNWISYLASKEGMVIALVDGRGTAFQGDKLLYAVYRKLGVYEVEDQITAVRKFIE 609 +VF +NW +YLAS E +++A DGRG+ +QGDK+++A+ R+LG +EVEDQI A R+F + Sbjct: 556 DTVFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINRRLGTFEVEDQIEAARQFSK 615 Query: 610 MGFIDEKRIAIWGWSYGGYVSSLALASGTGLFKCGIAVAPVSSWEYYASVYTERFMGLPT 669 MGF+D KRIAIWGWSYGGYV+S+ L SG+G+FKCGIAVAPVS WEYY SVYTER+MGLPT Sbjct: 616 MGFVDNKRIAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSRWEYYDSVYTERYMGLPT 675 Query: 670 KDDNLEHYKNSTVMARAEYFRNVDYLLIHGTADDNVHFQNSAQIAKALVNAQVDFQAMWY 729 +DNL+HY+NSTVM+RAE F+ V+YLLIHGTADDNVHFQ SAQI+KALV+ VDFQAMWY Sbjct: 676 PEDNLDHYRNSTVMSRAENFKQVEYLLIHGTADDNVHFQQSAQISKALVDVGVDFQAMWY 735 Query: 730 SDQNHGL-SGLSTNHLYTHMTHFLKQCFSL 758 +D++HG+ S + H+YTHM+HF+KQCFSL Sbjct: 736 TDEDHGIASSTAHQHIYTHMSHFIKQCFSL 765 >1Z68-A nrPDB Length = 719 Score = 971 bits (2510), Expect = 0.0, Method: Composition-based stats. Identities = 719/719 (100%), Positives = 719/719 (100%) Query: 39 MRALTLKDILNGTFSYKTFFPNWISGQEYLHQSADNNIVLYNIETGQSYTILSNRTMKSV 98 MRALTLKDILNGTFSYKTFFPNWISGQEYLHQSADNNIVLYNIETGQSYTILSNRTMKSV Sbjct: 1 MRALTLKDILNGTFSYKTFFPNWISGQEYLHQSADNNIVLYNIETGQSYTILSNRTMKSV 60 Query: 99 NASNYGLSPDRQFVYLESDYSKLWRYSYTATYYIYDLSNGEFVRGNELPRPIQYLCWSPV 158 NASNYGLSPDRQFVYLESDYSKLWRYSYTATYYIYDLSNGEFVRGNELPRPIQYLCWSPV Sbjct: 61 NASNYGLSPDRQFVYLESDYSKLWRYSYTATYYIYDLSNGEFVRGNELPRPIQYLCWSPV 120 Query: 159 GSKLAYVYQNNIYLKQRPGDPPFQITFNGRENKIFNGIPDWVYEEEMLATKYALWWSPNG 218 GSKLAYVYQNNIYLKQRPGDPPFQITFNGRENKIFNGIPDWVYEEEMLATKYALWWSPNG Sbjct: 121 GSKLAYVYQNNIYLKQRPGDPPFQITFNGRENKIFNGIPDWVYEEEMLATKYALWWSPNG 180 Query: 219 KFLAYAEFNDTDIPVIAYSYYGDEQYPRTINIPYPKAGAKNPVVRIFIIDTTYPAYVGPQ 278 KFLAYAEFNDTDIPVIAYSYYGDEQYPRTINIPYPKAGAKNPVVRIFIIDTTYPAYVGPQ Sbjct: 181 KFLAYAEFNDTDIPVIAYSYYGDEQYPRTINIPYPKAGAKNPVVRIFIIDTTYPAYVGPQ 240 Query: 279 EVPVPAMIASSDYYFSWLTWVTDERVCLQWLKRVQNVSVLSICDFREDWQTWDCPKTQEH 338 EVPVPAMIASSDYYFSWLTWVTDERVCLQWLKRVQNVSVLSICDFREDWQTWDCPKTQEH Sbjct: 241 EVPVPAMIASSDYYFSWLTWVTDERVCLQWLKRVQNVSVLSICDFREDWQTWDCPKTQEH 300 Query: 339 IEESRTGWAGGFFVSTPVFSYDAISYYKIFSDKDGYKHIHYIKDTVENAIQITSGKWEAI 398 IEESRTGWAGGFFVSTPVFSYDAISYYKIFSDKDGYKHIHYIKDTVENAIQITSGKWEAI Sbjct: 301 IEESRTGWAGGFFVSTPVFSYDAISYYKIFSDKDGYKHIHYIKDTVENAIQITSGKWEAI 360 Query: 399 NIFRVTQDSLFYSSNEFEEYPGRRNIYRISIGSYPPSKKCVTCHLRKERCQYYTASFSDY 458 NIFRVTQDSLFYSSNEFEEYPGRRNIYRISIGSYPPSKKCVTCHLRKERCQYYTASFSDY Sbjct: 361 NIFRVTQDSLFYSSNEFEEYPGRRNIYRISIGSYPPSKKCVTCHLRKERCQYYTASFSDY 420 Query: 459 AKYYALVCYGPGIPISTLHDGRTDQEIKILEENKELENALKNIQLPKEEIKKLEVDEITL 518 AKYYALVCYGPGIPISTLHDGRTDQEIKILEENKELENALKNIQLPKEEIKKLEVDEITL Sbjct: 421 AKYYALVCYGPGIPISTLHDGRTDQEIKILEENKELENALKNIQLPKEEIKKLEVDEITL 480 Query: 519 WYKMILPPQFDRSKKYPLLIQVYGGPCSQSVRSVFAVNWISYLASKEGMVIALVDGRGTA 578 WYKMILPPQFDRSKKYPLLIQVYGGPCSQSVRSVFAVNWISYLASKEGMVIALVDGRGTA Sbjct: 481 WYKMILPPQFDRSKKYPLLIQVYGGPCSQSVRSVFAVNWISYLASKEGMVIALVDGRGTA 540 Query: 579 FQGDKLLYAVYRKLGVYEVEDQITAVRKFIEMGFIDEKRIAIWGWSYGGYVSSLALASGT 638 FQGDKLLYAVYRKLGVYEVEDQITAVRKFIEMGFIDEKRIAIWGWSYGGYVSSLALASGT Sbjct: 541 FQGDKLLYAVYRKLGVYEVEDQITAVRKFIEMGFIDEKRIAIWGWSYGGYVSSLALASGT 600 Query: 639 GLFKCGIAVAPVSSWEYYASVYTERFMGLPTKDDNLEHYKNSTVMARAEYFRNVDYLLIH 698 GLFKCGIAVAPVSSWEYYASVYTERFMGLPTKDDNLEHYKNSTVMARAEYFRNVDYLLIH Sbjct: 601 GLFKCGIAVAPVSSWEYYASVYTERFMGLPTKDDNLEHYKNSTVMARAEYFRNVDYLLIH 660 Query: 699 GTADDNVHFQNSAQIAKALVNAQVDFQAMWYSDQNHGLSGLSTNHLYTHMTHFLKQCFS 757 GTADDNVHFQNSAQIAKALVNAQVDFQAMWYSDQNHGLSGLSTNHLYTHMTHFLKQCFS Sbjct: 661 GTADDNVHFQNSAQIAKALVNAQVDFQAMWYSDQNHGLSGLSTNHLYTHMTHFLKQCFS 719 >2AJB-A nrPDB Length = 728 Score = 960 bits (2482), Expect = 0.0, Method: Composition-based stats. Identities = 390/729 (53%), Positives = 528/729 (72%), Gaps = 10/729 (1%) Query: 38 TMRALTLKDILNGTFSYKTFFPNWISGQEYLHQSADNNIVLYNIETGQSYTILSNRTMKS 97 + R TL D L TF K + WIS EYL++ +NNI+L+N E G S L N T Sbjct: 1 SRRTYTLTDYLKSTFRVKFYTLQWISDHEYLYKQ-ENNILLFNAEYGNSSIFLENSTFDE 59 Query: 98 VNAS--NYGLSPDRQFVYLESDYSKLWRYSYTATYYIYDLSNGEFVRGNELPRPIQYLCW 155 + S +Y +SPDRQF+ E +Y K WR+SYTA+Y IYDL+ + + +P Q++ W Sbjct: 60 LGYSTNDYSVSPDRQFILFEYNYVKQWRHSYTASYDIYDLNKRQLITEERIPNNTQWITW 119 Query: 156 SPVGSKLAYVYQNNIYLKQRPGDPPFQITFNGRENKIFNGIPDWVYEEEMLATKYALWWS 215 SPVG KLAYV+ N+IY+K P +IT+ G+EN I+NG+ DWVYEEE+ + ALWWS Sbjct: 120 SPVGHKLAYVWNNDIYVKNEPNLSSQRITWTGKENVIYNGVTDWVYEEEVFSAYSALWWS 179 Query: 216 PNGKFLAYAEFNDTDIPVIAYSYYGDE--QYPRTINIPYPKAGAKNPVVRIFIIDT---T 270 PNG FLAYA+FNDT++P+I YS+Y DE QYP+T+ IPYPKAGA+NP V+ F++DT + Sbjct: 180 PNGTFLAYAQFNDTEVPLIEYSFYSDESLQYPKTVRIPYPKAGAENPTVKFFVVDTRTLS 239 Query: 271 YPAYVGPQEVPVPAMIASSDYYFSWLTWVTDERVCLQWLKRVQNVSVLSICDFREDWQTW 330 A V ++ PA + D+Y +TWVT+ER+ LQW++R QN S++ ICD+ E W Sbjct: 240 PNASVTSYQIVPPASVLIGDHYLCGVTWVTEERISLQWIRRAQNYSIIDICDYDESTGRW 299 Query: 331 DCPKTQEHIEESRTGWAGGFFVSTPVFSYDAISYYKIFSDKDGYKHIHYIKDTVENAIQI 390 ++HIE S TGW G F + P F+ D S+YKI S+++GYKHI + + N I Sbjct: 300 ISSVARQHIEISTTGWVGRFRPAEPHFTSDGNSFYKIISNEEGYKHICHFQTDKSNCTFI 359 Query: 391 TSGKWEAINIFRVTQDSLFYSSNEFEEYPGRRNIYRISIGSYPPSKKCVTCHLRKERCQY 450 T G WE I I +T D L+Y SNE + PG RN+YRI + Y C++C L ERCQY Sbjct: 360 TKGAWEVIGIEALTSDYLYYISNEHKGMPGGRNLYRIQLNDYT-KVTCLSCELNPERCQY 418 Query: 451 YTASFSDYAKYYALVCYGPGIPISTLHDGRTDQEIKILEENKELENALKNIQLPKEEIKK 510 Y+ASFS+ AKYY L C+GPG+P+ TLH +D+E+++LE+N L+ L+++Q+P +++ Sbjct: 419 YSASFSNKAKYYQLRCFGPGLPLYTLHSSSSDKELRVLEDNSALDKMLQDVQMPSKKLDV 478 Query: 511 LEVDEITLWYKMILPPQFDRSKKYPLLIQVYGGPCSQSVRSVFAVNWISYLASKEGMVIA 570 + + WY+MILPP FD+SKKYPLLI+VY GPCSQ V +VF ++W +YLAS E +++A Sbjct: 479 INLHGTKFWYQMILPPHFDKSKKYPLLIEVYAGPCSQKVDTVFRLSWATYLASTENIIVA 538 Query: 571 LVDGRGTAFQGDKLLYAVYRKLGVYEVEDQITAVRKFIEMGFIDEKRIAIWGWSYGGYVS 630 DGRG+ +QGDK+++A+ R+LG +EVEDQI A R+F +MGF+D+KRIAIWGWSYGGYV+ Sbjct: 539 SFDGRGSGYQGDKIMHAINRRLGTFEVEDQIEATRQFSKMGFVDDKRIAIWGWSYGGYVT 598 Query: 631 SLALASGTGLFKCGIAVAPVSSWEYYASVYTERFMGLPTKDDNLEHYKNSTVMARAEYFR 690 S+ L +G+G+FKCGIAVAPVS WEYY SVYTER+MGLPT +DNL++Y+NSTVM+RAE F+ Sbjct: 599 SMVLGAGSGVFKCGIAVAPVSKWEYYDSVYTERYMGLPTPEDNLDYYRNSTVMSRAENFK 658 Query: 691 NVDYLLIHGTADDNVHFQNSAQIAKALVNAQVDFQAMWYSDQNHGL-SGLSTNHLYTHMT 749 V+YLLIHGTADDNVHFQ SAQ++KALV+A VDFQ MWY+D++HG+ S ++ H+YTHM+ Sbjct: 659 QVEYLLIHGTADDNVHFQQSAQLSKALVDAGVDFQTMWYTDEDHGIASNMAHQHIYTHMS 718 Query: 750 HFLKQCFSL 758 HFLKQCFSL Sbjct: 719 HFLKQCFSL 727 >2GBG-A nrPDB Length = 730 Score = 947 bits (2448), Expect = 0.0, Method: Composition-based stats. Identities = 393/731 (53%), Positives = 527/731 (72%), Gaps = 13/731 (1%) Query: 39 MRALTLKDILNGTFSYKTFFPNWISGQEYLHQSADNNIVLYNIETGQSYTILSNRTMKSV 98 R TL D L TF K++ W+S EYL++ +NNI+L+N E G S L N T + Sbjct: 1 RRTYTLADYLKNTFRVKSYSLRWVSDSEYLYKQ-ENNILLFNAEHGNSSIFLENSTFEIF 59 Query: 99 N--ASNYGLSPDRQFVYLESDYSKLWRYSYTATYYIYDLSNGEFVRGNELPRPIQYLCWS 156 S+Y +SPDR FV LE +Y K WR+SYTA+Y IYDL+ + + ++P Q++ WS Sbjct: 60 GDSISDYSVSPDRLFVLLEYNYVKQWRHSYTASYSIYDLNKRQLITEEKIPNNTQWITWS 119 Query: 157 PVGSKLAYVYQNNIYLKQRPGDPPFQITFNGRENKIFNGIPDWVYEEEMLATKYALWWSP 216 G KLAYV++N+IY+K P P +IT G+EN IFNGI DWVYEEE+ ALWWSP Sbjct: 120 QEGHKLAYVWKNDIYVKIEPHLPSHRITSTGKENVIFNGINDWVYEEEIFGAYSALWWSP 179 Query: 217 NGKFLAYAEFNDTDIPVIAYSYYGDE--QYPRTINIPYPKAGAKNPVVRIFIIDTTYPAY 274 NG FLAYA+FNDT +P+I YS+Y DE QYP+T+ IPYPKAGA NP V+ FI++T + Sbjct: 180 NGTFLAYAQFNDTGVPLIEYSFYSDESLQYPKTVWIPYPKAGAVNPTVKFFIVNTDSLSS 239 Query: 275 VG---PQEVPVPAMIASSDYYFSWLTWVTDERVCLQWLKRVQNVSVLSICDFREDWQTWD 331 P ++ PA + + D+Y + WV+++R+ LQWL+R+QN SV++ICD+ + W+ Sbjct: 240 TTTTIPMQITAPASVTTGDHYLCDVAWVSEDRISLQWLRRIQNYSVMAICDYDKTTLVWN 299 Query: 332 CPKTQEHIEESRTGWAGGFFVSTPVFSYDAISYYKIFSDKDGYKHIHYIKDTVEN---AI 388 CP TQEHIE S TGW G F + P F+ D S+YKI SDKDGYKHI + + Sbjct: 300 CPTTQEHIETSATGWCGRFRPAEPHFTSDGSSFYKIVSDKDGYKHICQFQKDRKPEQVCT 359 Query: 389 QITSGKWEAINIFRVTQDSLFYSSNEFEEYPGRRNIYRISIGSYPPSKKCVTCHLRKERC 448 IT G WE I+I +T D L+Y SNE++E PG RN+Y+I + + +KKC++C L ERC Sbjct: 360 FITKGAWEVISIEALTSDYLYYISNEYKEMPGGRNLYKIQLTDHT-NKKCLSCDLNPERC 418 Query: 449 QYYTASFSDYAKYYALVCYGPGIPISTLHDGRTDQEIKILEENKELENALKNIQLPKEEI 508 QYY+ S S AKYY L C GPG+P+ TLH +E+++LE+N L+ L+++Q+P +++ Sbjct: 419 QYYSVSLSKEAKYYQLGCRGPGLPLYTLHRSTDQKELRVLEDNSALDKMLQDVQMPSKKL 478 Query: 509 KKLEVDEITLWYKMILPPQFDRSKKYPLLIQVYGGPCSQSVRSVFAVNWISYLASKEGMV 568 + ++E WY+MILPP FD+SKKYPLLI VY GPCSQ + F +NW +YLAS E ++ Sbjct: 479 DFIVLNETRFWYQMILPPHFDKSKKYPLLIDVYAGPCSQKADAAFRLNWATYLASTENII 538 Query: 569 IALVDGRGTAFQGDKLLYAVYRKLGVYEVEDQITAVRKFIEMGFIDEKRIAIWGWSYGGY 628 +A DGRG+ +QGDK+++A+ ++LG EVEDQI A R+F++MGF+D KR+AIWGWSYGGY Sbjct: 539 VASFDGRGSGYQGDKIMHAINKRLGTLEVEDQIEAARQFLKMGFVDSKRVAIWGWSYGGY 598 Query: 629 VSSLALASGTGLFKCGIAVAPVSSWEYYASVYTERFMGLPTKDDNLEHYKNSTVMARAEY 688 V+S+ L SG+G+FKCGIAVAPVS WEYY SVYTER+MGLPT +DNL+HY+NSTVM+RAE Sbjct: 599 VTSMVLGSGSGVFKCGIAVAPVSRWEYYDSVYTERYMGLPTPEDNLDHYRNSTVMSRAEN 658 Query: 689 FRNVDYLLIHGTADDNVHFQNSAQIAKALVNAQVDFQAMWYSDQNHGL-SGLSTNHLYTH 747 F+ V+YLLIHGTADDNVHFQ SAQI+KALV+A VDFQAMWY+D++HG+ S + H+Y+H Sbjct: 659 FKQVEYLLIHGTADDNVHFQQSAQISKALVDAGVDFQAMWYTDEDHGIASSTAHQHIYSH 718 Query: 748 MTHFLKQCFSL 758 M+HFL+QCFSL Sbjct: 719 MSHFLQQCFSL 729 >4WJL-A nrPDB Length = 719 Score = 812 bits (2096), Expect = 0.0, Method: Composition-based stats. Identities = 241/727 (33%), Positives = 396/727 (54%), Gaps = 24/727 (3%) Query: 42 LTLKDILNGTFSYKTFFPNWISGQEYLHQSADNNIVLYNIETGQSYTILSNRTMKSVNAS 101 L+L+D+ F WI+ + +++S + +++ NIET + +L N T + AS Sbjct: 5 LSLEDLFRKDFVLHDPEARWINDTDVVYKSENGHVIKLNIETNATTLLLENTTFVTFKAS 64 Query: 102 NYGLSPDRQFVYLESDYSKLWRYSYTATYYIYDLSNGEFV---RGNELPRPIQYLCWSPV 158 + +SPD ++V L D +++ YSYTA+Y IY++ E +QY W Sbjct: 65 RHSVSPDLKYVLLAYDVKQIFHYSYTASYVIYNIHTREVWELNPPEVEDSVLQYAAWGVQ 124 Query: 159 GSKLAYVYQNNIYLKQRPGDPPFQITFNGRENKIFNGIPDWVYEEEMLATKYALWWSPNG 218 G +L Y+++NNIY + ++T +G+E IFNGI DW+YEEE+L + A WWSP+G Sbjct: 125 GQQLIYIFENNIYYQPDIKSSSLRLTSSGKEEIIFNGIADWLYEEELLHSHIAHWWSPDG 184 Query: 219 KFLAYAEFNDTDIPVIAYSYYGDEQYPRTINIPYPKAGAKNPVVRIFIIDTTYPAYVGPQ 278 + LA+ ND+ +P + + YP+ PYPKAG NP +++++++ P + Sbjct: 185 ERLAFLMINDSLVPTMVIPRFTGALYPKGKQYPYPKAGQMNPTIKLYVVNLYGPTHT--L 242 Query: 279 EVPVPAMIASSDYYFSWLTWVTDERVCLQWLKRVQNVSVLSICDFREDWQTWDCPKTQEH 338 E+ P S +YY + + WV++ + ++WL R QN+S+L++C+ T C K E Sbjct: 243 ELMPPDSFKSREYYITMVKWVSNTKTVVRWLNRAQNISILTVCE----TTTGACSKKYEM 298 Query: 339 IEESRTGWAGGFFVSTPVFSYDAISYYKIFSDKDGYK----HIHYI----KDTVENAIQI 390 ++ PVFS D ++ K G + HI K + Sbjct: 299 TSDTWLSQQN----EEPVFSRDGSKFFMTVPVKQGGRGEFHHIAMFLIQSKSEQITVRHL 354 Query: 391 TSGKWEAINIFRVTQDSLFYSSNEFEEYPGRRNIYRISIGSYPPSKKCVTCHLRKERCQY 450 TSG WE I I + + E P R +Y S +++C++C+ KE+C Y Sbjct: 355 TSGNWEVIKILAYDETTQKIYFLSTESSPRGRQLYSASTEGLL-NRQCISCNFMKEQCTY 413 Query: 451 YTASFSDYAKYYALVCYGPGIPISTLHDGRTDQEIKILEENKELENALKNIQLPKEEIKK 510 + ASFS +++ L C GP +P+ +LH + ILE N L+ A+ ++ K EIK Sbjct: 414 FDASFSPMNQHFLLFCEGPRVPVVSLHSTDNPAKYFILESNSMLKEAILKKKIGKPEIKI 473 Query: 511 LEVDEITLWYKMILPPQFDRSKKYPLLIQVYGGPCSQSVRSVFAVNWISYLASKEGMVIA 570 L +D+ L ++ LP F +Y LL+ + P Q V F ++W S L + +++A Sbjct: 474 LHIDDYELPLQLSLPKDFMDRNQYALLLIMDEEPGGQLVTDKFHIDWDSVLIDMDNVIVA 533 Query: 571 LVDGRGTAFQGDKLLYAVYRKLGVYEVEDQITAVRKFIEMGFIDEKRIAIWGWSYGGYVS 630 DGRG+ FQG K+L ++R+LG EV+DQITAV+ +++ +ID KR++I+G YGGY++ Sbjct: 534 RFDGRGSGFQGLKILQEIHRRLGSVEVKDQITAVKFLLKLPYIDSKRLSIFGKGYGGYIA 593 Query: 631 SLALASGTGLFKCGIAVAPVSSWEYYASVYTERFMGLPTKDDNLEHYKNSTVMARAEYFR 690 S+ L S LFKCG VAP++ + YAS ++ER++G+P+K+++ Y+ ++V+ + Sbjct: 594 SMILKSDEKLFKCGSVVAPITDLKLYASAFSERYLGMPSKEEST--YQAASVLHNVHGLK 651 Query: 691 NVDYLLIHGTADDNVHFQNSAQIAKALVNAQVDFQAMWYSDQNHGLSGLSTNHLYTHMTH 750 + L+IHGTAD VHFQ+SA++ K L+ A V++ Y D+ H +S S HLY+ + Sbjct: 652 EENILIIHGTADTKVHFQHSAELIKHLIKAGVNYTMQVYPDEGHNVSEKSKYHLYSTILK 711 Query: 751 FLKQCFS 757 F C Sbjct: 712 FFSDCLK 718 >1XFD-A nrPDB Length = 723 Score = 792 bits (2044), Expect = 0.0, Method: Composition-based stats. Identities = 234/738 (31%), Positives = 397/738 (53%), Gaps = 34/738 (4%) Query: 39 MRALTLKDILNGTFSYKTFFPNWISGQEYLHQSADNNIVLYNIETGQSYTILSNRTMKSV 98 + +T++D+ + F WIS E++++ + L+N+ET S ++ + ++S+ Sbjct: 2 KKKVTVEDLFSEDFKIHDPEAKWISDTEFIYREQKGTVRLWNVETNTSTVLIEGKKIESL 61 Query: 99 NASNYGLSPDRQFVYLESDYSKLWRYSYTATYYIYDLSNGE---FVRGNELPRPIQYLCW 155 A Y +SPDR++ + ++++SYT Y + + +G+ +QY W Sbjct: 62 RAIRYEISPDREYALFSYNVEPIYQHSYTGYYVLSKIPHGDPQSLDPPEVSNAKLQYAGW 121 Query: 156 SPVGSKLAYVYQNNIYLKQRPGDPPFQITFNGRENKIFNGIPDWVYEEEMLATKYALWWS 215 P G +L ++++NNIY G ++ G+E I+NG+ DW+YEEE+L T A WWS Sbjct: 122 GPKGQQLIFIFENNIYYCAHVGKQAIRVVSTGKEGVIYNGLSDWLYEEEILKTHIAHWWS 181 Query: 216 PNGKFLAYAEFNDTDIPVIAYSYYGDEQYPRTINIPYPKAGAKNPVVRIFIIDTTYPAYV 275 P+G LAYA ND+ +P++ Y YP YPKAG++NP + + +I P + Sbjct: 182 PDGTRLAYAAINDSRVPIMELPTYTGSIYPTVKPYHYPKAGSENPSISLHVIGLNGPTH- 240 Query: 276 GPQEVPVPAMIASSDYYFSWLTWVTDERVCLQWLKRVQNVSVLSICDFREDWQTWDCPKT 335 E+ P +YY + + W T +V + WL R QNVS+L++CD T C T Sbjct: 241 -DLEMMPPDDPRMREYYITMVKWATSTKVAVTWLNRAQNVSILTLCDA----TTGVC--T 293 Query: 336 QEHIEESRTGWAGGFFVSTPVFSYDAISYYKIFSDKDGYKHIHY--------IKDTVENA 387 ++H +ES W PVFS D ++ I + G + Y + +N Sbjct: 294 KKHEDESE-AWLHRQ-NEEPVFSKDGRKFFFIRAIPQGGRGKFYHITVSSSQPNSSNDNI 351 Query: 388 IQITSGKWEAINIFRVTQD--SLFYSSNEFEEYPGRRNIYRISIGSYPPSKKCVTCHLRK 445 ITSG W+ I + +++ S E + P RR +Y + +++C++C L Sbjct: 352 QSITSGDWDVTKILAYDEKGNKIYFLSTE--DLPRRRQLYSANTVG-NFNRQCLSCDL-V 407 Query: 446 ERCQYYTASFSDYAKYYALVCYGPGIPISTLHDGRTDQEIKILEENKELENALKNIQLPK 505 E C Y++ASFS ++ L C GPG+P+ T+H+ +++ LE N+ ++ A+ + Q+PK Sbjct: 408 ENCTYFSASFSHSMDFFLLKCEGPGVPMVTVHNTTDKKKMFDLETNEHVKKAINDRQMPK 467 Query: 506 EEIKKLEVDEITLWYKMILPPQFDRSKKYPLLIQVYGGPCSQSVRSVFAVNWISYLASKE 565 E + +E+D+ L +++ P F + YPLL+ V G P SQSV F V+W + + S Sbjct: 468 VEYRDIEIDDYNLPMQILKPATFTDTTHYPLLLVVDGTPGSQSVAEKFEVSWETVMVSSH 527 Query: 566 GMVIALVDGRGTAFQGDKLLYAVYRKLGVYEVEDQITAVRKFIEMGFIDEKRIAIWGWSY 625 G V+ DGRG+ FQG KLL+ V R+LG+ E +DQ+ AVR ++ +ID R+A++G Y Sbjct: 528 GAVVVKCDGRGSGFQGTKLLHEVRRRLGLLEEKDQMEAVRTMLKEQYIDRTRVAVFGKDY 587 Query: 626 GGYVSSLALASGTG----LFKCGIAVAPVSSWEYYASVYTERFMGLPTKDDNLEHYKNST 681 GGY+S+ L + F CG A++P++ ++ YAS ++ER++GL D+ Y+ + Sbjct: 588 GGYLSTYILPAKGENQGQTFTCGSALSPITDFKLYASAFSERYLGLHGLDNRA--YEMTK 645 Query: 682 VMARAEYFRNVDYLLIHGTADDNVHFQNSAQIAKALVNAQVDFQAMWYSDQNHGLSGLS- 740 V R +L+IH TAD+ +HFQ++A++ L+ + ++ Y D++H + S Sbjct: 646 VAHRVSALEEQQFLIIHPTADEKIHFQHTAELITQLIRGKANYSLQIYPDESHYFTSSSL 705 Query: 741 TNHLYTHMTHFLKQCFSL 758 HLY + +F +CF + Sbjct: 706 KQHLYRSIINFFVECFRI 723 >5YP1-A nrPDB Length = 745 Score = 716 bits (1848), Expect = 0.0, Method: Composition-based stats. Identities = 181/771 (23%), Positives = 309/771 (40%), Gaps = 58/771 (7%) Query: 15 AVLALLVMCIVLRPSRVHNSEENTMRALTLKDILNG-TFSYKTFFPNWISGQEYLHQSAD 73 A+ AL + V H +E+ T+ A+T L+G T + P+ + D Sbjct: 4 ALFALFALITVATALPAH-AEKLTLEAITGSAPLSGPTLTKPQIAPDGSRVTFLRGKDRD 62 Query: 74 NNIV---LYNIETGQSYTILSNRTM---KSVNASNYGLSPDRQFVYLES---DY-----S 119 N + Y+I +GQ+ ++ + + + V + +RQ + S DY Sbjct: 63 RNRLDLWEYDIASGQTRLLVDSSVVLPGEEVLSDEEKARRERQRIAALSGIVDYQWSPDG 122 Query: 120 KLWRYSYTATYYIYDLSNGEFVRGNELPRPIQYLC---WSPVGSKLAYVYQNNIYLKQRP 176 K + Y YDL+ +L + SP G ++++ N++ Sbjct: 123 KALLFPLGGELYFYDLTKSGRDAVRKLTNGGGFATDPKISPKGGFVSFIRDRNLWAIDLA 182 Query: 177 GDPPFQITFNGRENKIFNGIPDWVYEEEMLATKYALWWSPNGKFLAYAEFNDTDIPVIA- 235 Q+T +G + I NG+ ++V +EEM WW+P+ +A+A ++T +PV Sbjct: 183 SGKEVQLTRDG-SDTIGNGVAEFVADEEM-DRHTGYWWAPDDAAIAFARIDETPVPVQKR 240 Query: 236 YSYYGDEQYPRTINIPYPKAGAKNPVVRIFIIDTTYPAYVGPQEVPVPAMIASSDYYFSW 295 Y Y D + YP AG N V++ +I + D Y + Sbjct: 241 YEVYPDRT--EVVEQRYPAAGDHNVRVQLGVIAPK-----TGARPRWIDLGKDPDIYLAR 293 Query: 296 LTWVTDERVCLQWLKRVQNVSVLSICDFREDWQTWDCPKTQEHIEESRTGWAGGFFVSTP 355 + W +R+ Q R Q L Q + + E+ T W + Sbjct: 294 VDWRDPQRLTFQRQSRDQKKIELIETTLTNGTQ-------RTLVTETSTTWVP--LHNDL 344 Query: 356 VFSYDAISYYKIFSDKDGYKHIHYIKDTVENAIQITSGKWEAINIFRVTQDSLFYSSNEF 415 F D + S++ G++H++ + +T G+W ++ + + + + Sbjct: 345 RFLKDGR--FLWSSERSGFEHLYVASEDGSTLTALTQGEWVVDSLLAIDEAAGLAYVSGT 402 Query: 416 EEYPGRRNIYRISIGSYPPSKKCVTCHLRKERCQYYTASF-----SDYAKYYALVCYGPG 470 + ++Y + + P + + + F SD + G Sbjct: 403 RDGATEAHVYAVPLSGGEPRRLTQAPGMHAATFARNASVFVDSWSSDTTLPQIELFKADG 462 Query: 471 IPISTLHDGRTDQEIKILEENKELENALKNIQLPKEEIKKLEVDEIT-LWYKMILPPQFD 529 ++TL + + + + P D T L Y +I P FD Sbjct: 463 TKLATLL-------VNDVSDATHPYAKYRAAHQPTAYGTLTAADGTTPLHYSLIKPAGFD 515 Query: 530 RSKKYPLLIQVYGGPCSQSVRSVFAVNWISYL---ASKEGMVIALVDGRGTAFQGDKLLY 586 K+YP+++ VYGGP +Q+V + S+ +++G V+ +D RGT +G Sbjct: 516 PKKQYPVVVFVYGGPAAQTVTRAWPGRSDSFFNQYLAQQGYVVFTLDNRGTPRRGAAFGG 575 Query: 587 AVYRKLGVYEVEDQITAVRKFIEMGFIDEKRIAIWGWSYGGYVSSLALASGTGLFKCGIA 646 A+Y K G EV+DQ+ + F+D RI ++GWS GGY++ + LA + CG+A Sbjct: 576 ALYGKQGTVEVDDQLRGIEWLKSQAFVDPARIGVYGWSNGGYMTLMLLAKHDEAYACGVA 635 Query: 647 VAPVSSWEYYASVYTERFMGLPTKDDNLEHYKNSTVMARAEYFRNVDYLLIHGTADDNVH 706 APV+ W Y + YTER+M LP N Y+ ++V + LLIHG ADDNV Sbjct: 636 GAPVTDWALYDTHYTERYMDLPKA--NEAGYREASVFTHVDGIGAGKLLLIHGMADDNVL 693 Query: 707 FQNSAQIAKALVNAQVDFQAMWYSDQNHGLSGLSTNHLYTHMTHFLKQCFS 757 F NS ++ L F+ M Y HGL G H Y F +C Sbjct: 694 FTNSTKLMSELQKRGTPFELMTYPGAKHGLRGSDLLHRYRLTEDFFARCLK 744 >5OLJ-A nrPDB Length = 723 Score = 700 bits (1806), Expect = 0.0, Method: Composition-based stats. Identities = 228/752 (30%), Positives = 362/752 (48%), Gaps = 56/752 (7%) Query: 16 VLALLVMCIVLRPSRVHNSEENTMRALTLKDILNGTF---SYKTFFPNWISGQEYLHQSA 72 +L ++ MC + + + + LK+I +G F S + G+ Y + Sbjct: 9 LLGIVTMCAMAQTGD---------KPVDLKEITSGMFYARSAGRGIRSMPDGEHYTEMNR 59 Query: 73 DNN-IVLYNIETGQS----YTILSNRTMKSVNASNYGLSPDRQFVYLESDYSKLWRYSYT 127 + IV YN +G++ ++I R NY +S + L +D ++R+SY Sbjct: 60 ERTAIVRYNYASGKAVDTLFSIERARECPFKQIQNYEVSSTGHHILLFTDMESIYRHSYR 119 Query: 128 ATYYIYDLSNGEFVRGNELPRPIQYLCWSPVGSKLAYVYQNNIYLKQRPGDPPFQITFNG 187 A Y YD+ +E + +SP G +A+V NNI++K+ D Q+T +G Sbjct: 120 AAVYDYDVRRNLVKPLSEHVGKVMIPTFSPDGRMVAFVRDNNIFIKKFDFDTEVQVTTDG 179 Query: 188 RENKIFNGIPDWVYEEEMLATKYALWWSPNGKFLAYAEFNDTDIPVIAYSYYGDEQYPRT 247 + N + NG DWVYEEE T + WS + FLA+ +++ +P Y D+ YP Sbjct: 180 QINSVLNGATDWVYEEEFGVTNL-MSWSADNAFLAFVRSDESAVPEYRMPMYEDKLYPED 238 Query: 248 INIPYPKAGAKNPVVRIFIIDTTYPAYVGPQEVPVPAMIASSDYYFSWLTWVTD-ERVCL 306 YPKAG KN V + + + V + ++ +D Y + + + + + + Sbjct: 239 YTYKYPKAGEKNSTVSLHLYN------VADRNTKSVSLPIDADGYIPRIAFTDNADELAV 292 Query: 307 QWLKRVQNVSVLSICDFREDWQTWDCPKTQEHIEESRTGWAGGFFVSTPVFSYDAISYYK 366 L R+QN DF+ + + +++ + ++ F+ + Sbjct: 293 MTLNRLQN-------DFKMYYVHPKSLVPKLILQDMNKRYVDSDWIQALKFTAGGG--FA 343 Query: 367 IFSDKDGYKHIHYIKDTVENAIQITSGKWEAINIFRVT-QDSLFYSSNEFEEYPGRRNIY 425 S+KDG+ HI+ + +ITSG W+ ++ V ++FY S E E P RR +Y Sbjct: 344 YVSEKDGFAHIYLYDNKGVMHRRITSGNWDVTKLYGVDASGTVFYQSAE--ESPIRRAVY 401 Query: 426 RISIGSYPPSKKCVTCHLRKERCQYYTASFSDYAKYYALVCYGPGIP-ISTLHDGRTDQE 484 I K ++ ++ A FS YY P + ++ + +E Sbjct: 402 AIDAKG---RKTKLSLNVGTN-----DALFSGNYAYYINTYSSAATPTVVSVFRSKGAKE 453 Query: 485 IKILEENKELENALKNIQLPKEE---IKKLEVDEITLWYKMILPPQFDRSKKYPLLIQVY 541 ++ LE+N L LK + +E IK E+ W ++ P FD S+ YP+L+ Y Sbjct: 454 LRTLEDNVALRERLKAYRYNPKEFTIIKTQSALELNAW--IVKPIDFDPSRHYPVLMVQY 511 Query: 542 GGPCSQSVRSVFAVNWISYLASKEGMVIALVDGRGTAFQGDKLLYAVYRKLGVYEVEDQI 601 GP SQ V ++ +W YLASK G V+A VDGRGT +G++ Y +LGV+E +DQI Sbjct: 512 SGPNSQQVLDRYSFDWEHYLASK-GYVVACVDGRGTGARGEEWRKCTYMQLGVFESDDQI 570 Query: 602 TAVRKFIEMGFIDEKRIAIWGWSYGGYVSSLALASGTGLFKCGIAVAPVSSWEYYASVYT 661 A ++ ++D RI IWGWSYGGY + ++L G G FK GIAVAPV+ W +Y SVYT Sbjct: 571 AAATAIGQLPYVDAARIGIWGWSYGGYTTLMSLCRGNGTFKAGIAVAPVADWRFYDSVYT 630 Query: 662 ERFMGLPTKDDNLEHYKNSTVMARAEYFRNVDYLLIHGTADDNVHFQNSAQIAKALVNAQ 721 ERFM P +N YK S+ + A + + L++ G+ADDNVH QN+ +ALV A Sbjct: 631 ERFMRTPK--ENASGYKMSSALDVASQLQG-NLLIVSGSADDNVHLQNTMLFTEALVQAN 687 Query: 722 VDFQAMWYSDQNHGLSGLS-TNHLYTHMTHFL 752 + F Y D+NH + G + HLYT FL Sbjct: 688 IPFDMAIYMDKNHSIYGGNTRYHLYTRKAKFL 719 >2ECF-A nrPDB Length = 741 Score = 669 bits (1725), Expect = 0.0, Method: Composition-based stats. Identities = 196/775 (25%), Positives = 325/775 (41%), Gaps = 79/775 (10%) Query: 21 VMCIVLRPSRVHNSEENTMRALTLKDILNG-TFSYKTFFPNWISGQEYLHQSADNNIV-- 77 + +L S V ++E+ T+ A+T L+G T P+ + +D N + Sbjct: 7 SLAFMLATSTVAHAEKLTLEAITGPLPLSGPTLMKPKVAPDGSRVTFLRGKDSDRNQLDL 66 Query: 78 -LYNIETGQSYTILSNRTM---KSVNASNYGLSPDRQFVYLES---DYS-----KLWRYS 125 Y+I +GQ+ ++ ++ + + +RQ + + DY + + Sbjct: 67 WSYDIGSGQTRLLVDSKVVLPGTETLSDEEKARRERQRIAAMTGIVDYQWSPDAQRLLFP 126 Query: 126 YTATYYIYDLSNGEFVRGNELPRPIQYLC---WSPVGSKLAYVYQNNIYLKQRPGDPPFQ 182 Y+YDL +L + SP G ++++ N+++ Q Sbjct: 127 LGGELYLYDLKQEGKAAVRQLTHGEGFATDAKLSPKGGFVSFIRGRNLWVIDLASGRQMQ 186 Query: 183 ITFNGRENKIFNGIPDWVYEEEMLATKYALWWSPNGKFLAYAEFNDTDIPVIA-YSYYGD 241 +T +G I NGI ++V +EEM WW+P+ +AYA +++ +PV Y Y D Sbjct: 187 LTADG-STTIGNGIAEFVADEEM-DRHTGYWWAPDDSAIAYARIDESPVPVQKRYEVYAD 244 Query: 242 EQYPRTINIPYPKAGAKNPVVRIFIIDTTYPAYVGPQEVPVPAMIASSDYYFSWLTWVTD 301 I YP AG N V++ +I A + + D Y + + W Sbjct: 245 RT--DVIEQRYPAAGDANVQVKLGVISPAEQA-----QTQWIDLGKEQDIYLARVNWRDP 297 Query: 302 ERVCLQWLKRVQNVSVLSICDFREDWQTWDCPKTQEHIEESRTGWAGGFFVSTPVFSYDA 361 + + Q R Q L + Q + E+ W ++ F D Sbjct: 298 QHLSFQRQSRDQKKLDLVEVTLASNQQ-------RVLAHETSPTWVP--LHNSLRFLDDG 348 Query: 362 ISYYKIFSDKDGYKHIHYIKDTVENAIQITSGKWEAINIFRVTQDSLFYSSNEFEEYPGR 421 S++ G++H++ I D+ A +T G W + V + + E Sbjct: 349 S--ILWSSERTGFQHLYRI-DSKGKAAALTHGNWSVDELLAVDEKAGLAYFRAGIESARE 405 Query: 422 RNIYRISIGSYPPSKKCVTCHLRKERCQYYTASFSDYAKYYALVCYGPGIPISTLHDGRT 481 IY + + P + + ++ASF+ A Y + + + T Sbjct: 406 SQIYAVPLQGGQPQRLSKAPGM-------HSASFARNASVY----------VDSWSNNST 448 Query: 482 DQEIKILEENKE-----LENALKNIQLP----KEEIKKLEVDEIT-------LWYKMILP 525 +I++ N E +EN L + + P +E + +E +T L Y +I P Sbjct: 449 PPQIELFRANGEKIATLVENDLADPKHPYARYREAQRPVEFGTLTAADGKTPLNYSVIKP 508 Query: 526 PQFDRSKKYPLLIQVYGGPCSQSVRSVFAVNWISYL---ASKEGMVIALVDGRGTAFQGD 582 FD +K+YP+ + VYGGP SQ+V + +++G V+ +D RGT +G Sbjct: 509 AGFDPAKRYPVAVYVYGGPASQTVTDSWPGRGDHLFNQYLAQQGYVVFSLDNRGTPRRGR 568 Query: 583 KLLYAVYRKLGVYEVEDQITAVRKFIEMGFIDEKRIAIWGWSYGGYVSSLALASGTGLFK 642 A+Y K G EV DQ+ V + ++D RI + GWS GGY++ + LA + + Sbjct: 569 DFGGALYGKQGTVEVADQLRGVAWLKQQPWVDPARIGVQGWSNGGYMTLMLLAKASDSYA 628 Query: 643 CGIAVAPVSSWEYYASVYTERFMGLPTKDDNLEHYKNSTVMARAEYFRNVDYLLIHGTAD 702 CG+A APV+ W Y S YTER+M LP ++D Y+ + V+ E R+ LLIHG AD Sbjct: 629 CGVAGAPVTDWGLYDSHYTERYMDLPARND--AGYREARVLTHIEGLRS-PLLLIHGMAD 685 Query: 703 DNVHFQNSAQIAKALVNAQVDFQAMWYSDQNHGLSGLSTNHLYTHMTHFLKQCFS 757 DNV F NS + AL F+ M Y HGLSG H Y FL +C Sbjct: 686 DNVLFTNSTSLMSALQKRGQPFELMTYPGAKHGLSGADALHRYRVAEAFLGRCLK 740 >2EEP-A nrPDB Length = 706 Score = 629 bits (1623), Expect = e-180, Method: Composition-based stats. Identities = 175/743 (23%), Positives = 309/743 (41%), Gaps = 82/743 (11%) Query: 47 ILNGTFSYKTFFPNWISGQEYLHQS---ADNNIVLYNIETGQSYTILSNRTMKSVNASNY 103 ++ G + F+P ++ G +++ + + + +++N G+S +T + A Sbjct: 13 LMPGGKEFYNFYPEYVVGLQWMGDNYVFIEGDDLVFNKANGKS-----AQTTRFSAADLN 67 Query: 104 GLSPDRQFVYLESDYSKLWRYSYTATYYIYDLSNGEFVRGNELPRPIQYLC--------- 154 L P+ + +D +R + + G V + L R + YL Sbjct: 68 ALMPEG-CKFQTTDAFPSFRTLDAGRGLVVLFTQGGLVGFDMLARKVTYLFDTNEETASL 126 Query: 155 -WSPVGSKLAYVYQNNIYLKQ-----RPGDPPFQITFNGRENKIFNGIPDWVYEEEMLAT 208 +SPVG ++AYV +N+Y+ + +T +G E ++ V++ E Sbjct: 127 DFSPVGDRVAYVRNHNLYIARGGKLGEGMSRAIAVTIDGTETLVYG---QAVHQREFGIE 183 Query: 209 KYALWWSPNGKFLAYAEFNDTDI---PVIAYSYYGDEQYPRTINIPYPKAG--AKNPVVR 263 K +WSP G LA+ + + + P++ Y E P + YP AG + + V Sbjct: 184 K-GTFWSPKGSCLAFYRMDQSMVKPTPIVDYHPLEAESKP----LYYPMAGTPSHHVTVG 238 Query: 264 IFIIDTTYPAYVGPQEVPVPAMIASSDYYFSWLTWVTDERV-CLQWLKRVQNVSVLSICD 322 I+ + T Y+ E + + + L+W DE + + + R QN ++ D Sbjct: 239 IYHLATGKTVYLQTGE--------PKEKFLTNLSWSPDENILYVAEVNRAQNECKVNAYD 290 Query: 323 FREDW--QTWDCPKTQEHIEESRTGWAGGFFVSTPVFSYDAISYYKIFSDKDGYKHIHYI 380 +T + ++E + F + + + S +DG+ H++ Sbjct: 291 AETGRFVRTLFVETDKHYVEP----------LHPLTFLPGSNNQFIWQSRRDGWNHLYLY 340 Query: 381 KDTVENAIQITSGKWEAINI--FRVTQDSLFYSSNEFEEYPGRRNIYRISIGSYPPSKKC 438 T Q+T G+WE N F L++ S E P R+ Y I I Sbjct: 341 DTTGRLIRQVTKGEWEVTNFAGFDPKGTRLYFESTEA--SPLERHFYCIDIKGG------ 392 Query: 439 VTCHLRKERCQYYTASFSDYAKYYALVCYGPGIP--ISTLHDGRTDQEIKILEENKELEN 496 T L E + T D + + P +P ++ + G+ L E K + Sbjct: 393 KTKDLTPESGMHRTQLSPDGSA-IIDIFQSPTVPRKVTVTNIGKGSH---TLLEAKNPDT 448 Query: 497 ALKNIQLPKEEIKKLEVDEITLWYKMILPPQFDRSKKYPLLIQVYGGPCSQSVRSVFA-- 554 ++ I + + L+YK+ +P FD +KKYP+++ VYGGP +Q V + Sbjct: 449 GYAMPEIRTGTIMAAD-GQTPLYYKLTMPLHFDPAKKYPVIVYVYGGPHAQLVTKTWRSS 507 Query: 555 -VNWISYLASKEGMVIALVDGRGTAFQGDKLLYAVYRKLGVYEVEDQITAVRKFIEMGFI 613 W Y+A K G + VD RG+A +G ++R+LG E+ DQ+ V ++ Sbjct: 508 VGGWDIYMAQK-GYAVFTVDSRGSANRGAAFEQVIHRRLGQTEMADQMCGVDFLKSQSWV 566 Query: 614 DEKRIAIWGWSYGGYVSSLALASGTGLFKCGIAVAPVSSWEYYASVYTERFMGLPTKDDN 673 D RI + GWSYGG++++ + + +FK G+A PV W Y +Y ER+ P +N Sbjct: 567 DADRIGVHGWSYGGFMTTNLMLTHGDVFKVGVAGGPVIDWNRYEIMYGERYFDAP--QEN 624 Query: 674 LEHYKNSTVMARAEYFRNVDYLLIHGTADDNVHFQNSAQIAKALVNAQVDFQAMWYSDQN 733 E Y + ++ RA + +LIHG D V +Q+S A V A+ Y Sbjct: 625 PEGYDAANLLKRAGDLKG-RLMLIHGAIDPVVVWQHSLLFLDACVKARTYPDYYVYPSHE 683 Query: 734 HGLSGLSTNHLYTHMTHFLKQCF 756 H + G HLY +T + Sbjct: 684 HNVMGPDRVHLYETITRYFTDHL 706 >4Q1V-A nrPDB Length = 710 Score = 576 bits (1484), Expect = e-164, Method: Composition-based stats. Identities = 167/756 (22%), Positives = 307/756 (40%), Gaps = 89/756 (11%) Query: 40 RALTLKDILNGTFSYKTFFPNWISGQEYLHQS--ADNNIVLYNIE--TGQSYTILSNRTM 95 + TL++++ G SY + + G ++ LY+I+ TG+ +++ + Sbjct: 5 KKPTLEELIPGGESY--LYAENLYGLQWWGDECIKPGVDTLYSIQPKTGKETMVITREQI 62 Query: 96 KSVNASNYGLSPDRQF-VYLESDYSKLWRYSYTATYYIYDLSNGEFVRGNELPRPIQYLC 154 V N + V ++ + +Y+ N + V + Sbjct: 63 NKVLEENKAGKLSHLYSVRFPWTDKAQMLFTIAGKFIVYNFKNNQVVSTFKPKDGANNED 122 Query: 155 WSPVGSKLAYVYQNNIYLKQRPGDPPFQITFNGRENKIFNGIPDWVYEEEMLATKYALWW 214 + +AY NN+Y+ ++ I G V+ E K +W Sbjct: 123 YCAASGNVAYTIDNNLYVNEKA--------VTNEPEGIVCG--QTVHRNEFGINK-GTFW 171 Query: 215 SPNGKFLAYAEFNDTDI---PVIAYSYYGDEQYPRTINIPYPKAGAKNPVVRIFIID--T 269 SP G LA+ +++ + P++ + + N+ YP AG + V++ I + T Sbjct: 172 SPKGNLLAFYRMDESMVTQYPLVDIT----ARVGEVNNVRYPMAGMTSHQVKVGIYNPAT 227 Query: 270 TYPAYVGPQEVPVPAMIASSDYYFSWLTWVTDER-VCLQWLKRVQNVSVLSICDFR-EDW 327 Y+ + +D YF+ ++W DE+ + L + R QN + L C + E Sbjct: 228 GKSIYLNAGD--------PTDRYFTNISWAPDEKSLYLIEVNRDQNHAKL--CQYNAETG 277 Query: 328 QTWDCPKTQEHIEESRTGWAGGFFVSTPVFSYDAISYYKIFSDKDGYKHIHYIKDTVEN- 386 + + H + F P + S +DGY H++ + N Sbjct: 278 EPMGVLYEEMHPKYVEPQNPIVFLPWDPT-------KFIYQSQRDGYNHLYLFETNAANM 330 Query: 387 ------------------AIQITSGKWEAINI--FRVTQDSLFYSSNEFEEYPGRRNIYR 426 Q+T G W I F + + +++ E R + Sbjct: 331 KGETYNSANGGSYFQAGKVKQLTKGNWLVSEILGFNTKRKEVIFTAVEG----LRSGHFA 386 Query: 427 ISIGSYPPSKKCVTCHLRKERCQYYTASFSDYAKYYALVCYGPGIP-ISTLHDGRTDQEI 485 +++ + S+ C + ++ + S Y P + L D + +E Sbjct: 387 VNVSNGKISQPFENC-----KESEHSGTLSASGTYLIDRYSTKDQPRVINLVDTKNFKET 441 Query: 486 KILEENKELENALKNIQLPKEEIKKLEVDEIT--LWYKMILPPQFDRSKKYPLLIQVYGG 543 L EN Q+P E ++ + T L Y+++ P FD +KKYP+++ VYGG Sbjct: 442 ANLLTA---ENPYDGYQMPSIETGTIKAADGTTDLHYRLMKPANFDPAKKYPVIVYVYGG 498 Query: 544 PCSQSVRSVF---AVNWISYLASKEGMVIALVDGRGTAFQGDKLLYAVYRKLGVYEVEDQ 600 P +Q V + A W +Y+ASK G ++ +D RG++ +G A +R+LG+ E +DQ Sbjct: 499 PHAQCVTGGWQNGARGWDTYMASK-GYIMFTIDNRGSSNRGLTFENATFRRLGIEEGKDQ 557 Query: 601 ITAVRKFIEMGFIDEKRIAIWGWSYGGYVSSLALASGTGLFKCGIAVAPVSSWEYYASVY 660 + V + ++D +RI + GWS+GG++++ + +FK G+A PV W YY +Y Sbjct: 558 VKGVEFLKSLPYVDSERIGVHGWSFGGHMTTALMLRYPEIFKVGVAGGPVIDWGYYEIMY 617 Query: 661 TERFMGLPTKDDNLEHYKNSTVMARAEYFRNVDYLLIHGTADDNVHFQNSAQIAKALVNA 720 ER+M P + N E YK + A+ + L+IH DD Q++ KA V+A Sbjct: 618 GERYMDTP--ESNPEGYKECNLKNLADQLKG-HLLIIHDDHDDTCVPQHTLSFMKACVDA 674 Query: 721 QVDFQAMWYSDQNHGLSGLSTNHLYTHMTHFLKQCF 756 + Y H ++G HL+ +T + +Q Sbjct: 675 RTYPDLFIYPCHKHNVAGRDRVHLHEKITRYFEQNL 710 >6EOT-A nrPDB Length = 898 Score = 517 bits (1332), Expect = e-147, Method: Composition-based stats. Identities = 174/758 (22%), Positives = 298/758 (39%), Gaps = 119/758 (15%) Query: 100 ASNYGLSPDRQFV----YLESDYSK-LWRYSYTATYYIYDLSNGEFVRG-NELPRPIQYL 153 + L +R+ + DY + + + A IY + +G + RP Sbjct: 149 SREEELLRERKRIGTVGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVE 208 Query: 154 CWSP-----------VGSKLAYVYQNNIYLKQRPGDPPFQITF------NGRENKIFNGI 196 P +A+++ N+I++ ++T+ N E+ G+ Sbjct: 209 TSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGV 268 Query: 197 PDWVYEEEMLATKYALWWSPN-------GKFLA--YAEFNDTDIPVIAYSYYGDEQYPRT 247 +V +EE WW P GK L Y E +++++ +I + E R Sbjct: 269 ATFVLQEEF-DRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETR-RA 326 Query: 248 INIPYPKAGAKNPVVRI-----------FIIDTTYPAYVGPQEVPVPAM--IASSDYY-- 292 + YPK G NP V IID + P E+ + IA + + Sbjct: 327 DSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPE 386 Query: 293 --FSWLTWVTDERVCLQWLKRVQNVSVLSICDFREDWQTWD-CPKTQEHI---EESRTGW 346 ++W + + LQ + + + D E + + P + + EE+ W Sbjct: 387 GKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIW 446 Query: 347 AG--GFFVSTPVFSYDAISYYKIFSDKDGYKHIHY----------------------IKD 382 F P + I + K G++H++ K Sbjct: 447 INIHDIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKC 506 Query: 383 TVENAIQITSGKWEAIN---------------IFRVTQDSLFYSSNEFEEYPGRRNIYRI 427 ++ I ITSG+WE + F T+DS Y + R+ Sbjct: 507 PIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEVTRL 566 Query: 428 SIGSYPPSKKCVTCHLRKERCQYYTASFSDYAKYYALVCYGPGIPISTLHDGRTDQEIKI 487 + Y S C++ H C ++ + +S+ + + Y +S+ D T + + Sbjct: 567 TDRGYSHSC-CISQH-----CDFFISKYSNQKNPHCVSLY----KLSSPEDDPTCKTKEF 616 Query: 488 LEENKELENALKNIQLPKEEIKKLE-VDEITLWYKMILPPQFDRSKKYPLLIQVYGGPCS 546 + L + P EI E TL+ + P KKYP ++ +YGGP Sbjct: 617 WATILDSAGPLPDYTPP--EIFSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQV 674 Query: 547 QSVRSVFAVNWISYLA----SKEGMVIALVDGRGTAFQGDKLLYAVYRKLGVYEVEDQIT 602 Q V + F + Y + G V+ ++D RG+ +G K A K+G E++DQ+ Sbjct: 675 QLVNNRFKG--VKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVE 732 Query: 603 AVRKFIEM-GFIDEKRIAIWGWSYGGYVSSLALASGTGLFKCGIAVAPVSSWEYYASVYT 661 ++ FID R+ I GWSYGGY+S +AL + +F+ IA APV+ W +Y + YT Sbjct: 733 GLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYT 792 Query: 662 ERFMGLPTKDDNLEHYKNSTVMARAEYFRNVD--YLLIHGTADDNVHFQNSAQIAKALVN 719 ER+MG P D N + Y +V +AE F + LL+HG D+NVHF +++ + LV Sbjct: 793 ERYMGHP--DQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVR 850 Query: 720 AQVDFQAMWYSDQNHGLS-GLSTNHLYTHMTHFLKQCF 756 A + Y + H + S H H+ H+L++ Sbjct: 851 AGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENL 888 >6EOR-A nrPDB Length = 869 Score = 453 bits (1165), Expect = e-127, Method: Composition-based stats. Identities = 156/751 (20%), Positives = 286/751 (38%), Gaps = 96/751 (12%) Query: 88 TILSNRTMKSVNASNYGLSPD-RQFVYLESDYSKLWRYSYTATYYIYDLSNGEFVRGNEL 146 + + + ++Y + F++ S+ L+ + Sbjct: 127 LLRERKRLGVFGITSYDFHSESGLFLFQASN--SLFHCRDGGKNGFMVSPMKPLEIKTQC 184 Query: 147 PRPIQYLCWSPVG-SKLAYVYQNNIYLKQRPGDPPFQITF--NGRENKI----FNGIPDW 199 P P + +++ +++++ ++TF G N + G+ + Sbjct: 185 SGPRMDPKICPADPAFFSFINNSDLWVANIETGEERRLTFCHQGLSNVLDDPKSAGVATF 244 Query: 200 VYEEEMLATKYALWWSPNGK----------FLAYAEFNDTDIPVIAYSYYGDEQYPRTIN 249 V +EE WW P + Y E +++++ VI E+ +T + Sbjct: 245 VIQEEF-DRFTGYWWCPTASWEGSEGLKTLRILYEEVDESEVEVIHVPSPALEER-KTDS 302 Query: 250 IPYPKAGAKNPVVRIF-----------IIDTTYPAYVGPQEVPVP------AMIASSDYY 292 YP+ G+KNP + + I+ T V P P + D Sbjct: 303 YRYPRTGSKNPKIALKLAEFQTDSQGKIVSTQEKELVQPFSSLFPKVEYIARAGWTRDGK 362 Query: 293 FSWLTWVTDERVCLQWLKRVQNVSVLS----ICDFREDWQTWDCPKTQEHIEESRTGWAG 348 ++W ++ + LQ + + + S + EE W Sbjct: 363 YAWAMFLDRPQQWLQLVLLPPALFIPSTENEEQRLASARAVPRNVQPYVVYEEVTNVWIN 422 Query: 349 G---FFVSTPVFSYDAISYYKIFSDKDGYKHIHY----------------------IKDT 383 F+ D + + + K G+ H++ K Sbjct: 423 VHDIFYPFPQSEGEDELCFLRANECKTGFCHLYKVTAVLKSQGYDWSEPFSPGEDEFKCP 482 Query: 384 VENAIQITSGKWEAI-----NIFRVTQDSLFYSSNEFEEYPGRRNIYRISIGSYPPSKKC 438 ++ I +TSG+WE + I+ + L Y ++ P ++Y +S + + Sbjct: 483 IKEEIALTSGEWEVLARHGSKIWVNEETKLVYFQG-TKDTPLEHHLYVVSYEAAGEIVRL 541 Query: 439 VTCHLRKERCQYYTASFSDYAKYYALVCYGPGIPISTLHDGRTDQEIKILEENKELENAL 498 T C + +F + +Y+ V P + + L G D + ++ + + + Sbjct: 542 TTPGF-SHSCSM-SQNFDMFVSHYSSVSTPPCVHVYKL-SGPDDDPLH--KQPRFWASMM 596 Query: 499 KNIQLPK----EEIKKLEVDEITLWYKMILPPQ-FDRSKKYPLLIQVYGGPCSQSVRSVF 553 + P EI Y MI P KK+P ++ VYGGP Q V + F Sbjct: 597 EAASCPPDYVPPEIFHFHTRSDVRLYGMIYKPHALQPGKKHPTVLFVYGGPQVQLVNNSF 656 Query: 554 AVNWISYLA----SKEGMVIALVDGRGTAFQGDKLLYAVYRKLGVYEVEDQITAVRKFIE 609 I YL + G + ++DGRG+ +G + A+ ++G E+EDQ+ ++ E Sbjct: 657 KG--IKYLRLNTLASLGYAVVVIDGRGSCQRGLRFEGALKNQMGQVEIEDQVEGLQFVAE 714 Query: 610 M-GFIDEKRIAIWGWSYGGYVSSLALASGTGLFKCGIAVAPVSSWEYYASVYTERFMGLP 668 GFID R+AI GWSYGG++S + L +FK IA APV+ W Y + YTER+M +P Sbjct: 715 KYGFIDLSRVAIHGWSYGGFLSLMGLIHKPQVFKVAIAGAPVTVWMAYDTGYTERYMDVP 774 Query: 669 TKDDNLEHYKNSTVMARAEYFRNVD--YLLIHGTADDNVHFQNSAQIAKALVNAQVDFQA 726 ++N Y+ +V E N L++HG D+NVHF ++ + L+ A +Q Sbjct: 775 --ENNQHGYEAGSVALHVEKLPNEPNRLLILHGFLDENVHFFHTNFLVSQLIRAGKPYQL 832 Query: 727 MWYSDQNHGL-SGLSTNHLYTHMTHFLKQCF 756 Y ++ H + S H + HFL++ Sbjct: 833 QIYPNERHSIRCPESGEHYEVTLLHFLQEYL 863 >6IGR-A nrPDB Length = 656 Score = 230 bits (585), Expect = 2e-60, Method: Composition-based stats. Identities = 103/613 (16%), Positives = 200/613 (32%), Gaps = 83/613 (13%) Query: 153 LCWSPVGSKLAYVYQNN-----IYLKQRPGDPPFQITFNGRENKIFNGIPDWVYEEEMLA 207 WSP G LA+V + L G ++T NG+ Sbjct: 84 PRWSPDGQNLAFVRSAGEVKAALMLLPLKGGEARRVTH------FKNGVS---------- 127 Query: 208 TKYALWWSPNGKFLAYAEFNDTDIPVIAYSYYGDEQYPRTINIP-YPKAGAKNPVVRIFI 266 WSP+G+F+A+ DT+ + R + P Y GA Sbjct: 128 ---GPQWSPDGRFIAFTTTADTE------DKRDERGEARVLTRPVYRANGAD-------- 170 Query: 267 IDTTYPAYVGPQEVPVPAMIASSDYYFSWL-----TWVTDERVCLQWLKRVQNVSVLSIC 321 P + ++Y + +W D R L VQ+ Sbjct: 171 ---WLPERPAALWLYDVEADKLREWYAPEIGIGALSWWPDSRGVLI----VQSEDEWQAS 223 Query: 322 DFREDWQTWDCPKTQEHIEESRTGWAGGFFVSTPVFSYDAISYYKI--FSDKDGYKHIHY 379 +R+D P + D + I + K +H H Sbjct: 224 QWRQDVYDLPLPTADAPAAPQKLLDWNSAAHG-LAPHPDGQRFALIGRPAGKGNTEHAHL 282 Query: 380 IKDTVENAIQITSGKWEAINIFRVTQDSLFYSSNEFEEYPGRRNIYRISIGSYPPSKKCV 439 ++ +G + + G ++ ++ S Sbjct: 283 YLIENGQHRRLDTGHDHPVGDAVGGDCHVGAFPEGPRWLDGDTLLFSSTVRG---SVGLF 339 Query: 440 TCHLRKERCQYYTASFSDYAKYYALVCYGPGIPISTLHDGRTDQEIKILEENKELENALK 499 T H+ Y A G+ + R + + +L Sbjct: 340 TAHIGGGVKAY---DHDPQGVISAFTANEHGVALIRESATRFPEVELNGQRVTDLHARFP 396 Query: 500 -NIQLPKEEIKKLEVDEITLWYKMILPPQFDRSKKYPLLIQVYGGPCSQSVRSVFAVNWI 558 ++ P+ + E+ E W ++LP + +K P L+ ++GGP + + Sbjct: 397 FPVREPQRVTFETELGEGEGW--VLLP---EGEQKVPALLNIHGGPHTDYGHGF--THEF 449 Query: 559 SYLASKEGMVIALVDGRGTAFQGDKLLYAVYRKLGVYEVEDQITAVRKFIE-MGFIDEKR 617 +A++ G + + RG+ G + A+Y + G + +D + + +E + +D + Sbjct: 450 QLMAAR-GYGVCYSNPRGSVGYGQAWVDAIYGRWGTVDADDLLNFFDRCLEAVPRLDAAK 508 Query: 618 IAIWGWSYGGYVSSLALASGTGLFKCGIAVAPVSSWEYYASVYTERFMGLPTKDDN--LE 675 A+ G +YGG++++ + T F+ I +S+ + +GL DD L+ Sbjct: 509 TAVMGGAYGGFMTNW-ITGHTTRFQAAITDRCISNLISFGGTSD---IGLRFWDDELGLD 564 Query: 676 HYKNSTV-----MARAEYFRNV--DYLLIHGTADDNVHFQNSAQIAKALVNAQVDFQAMW 728 + + ++ +Y NV L++H D + + Q AL QV + + Sbjct: 565 FSRRADALKLWDLSPLQYVENVKTPTLIVHSVLDHRCPVEQAEQWYAALHKHQVPVRFVR 624 Query: 729 YSDQNHGLSGLST 741 + ++NH LS Sbjct: 625 FPEENHELSRSGR 637 Score = 44.8 bits (104), Expect = 1e-04, Method: Composition-based stats. Identities = 39/210 (18%), Positives = 69/210 (32%), Gaps = 34/210 (16%) Query: 15 AVLALLVMCIVLRPSRVHNSEENTMRALTLKDILNGTFSYKTFFPNWISGQEYLHQSADN 74 ++LAL + S + ++ +D + P + SG Sbjct: 14 SLLAL-AFPSDPQVSPDGKQVAFVLAQISEEDPAKPDKDFAR--PRYRSG---------- 60 Query: 75 NIVLYNIETGQSYTILSNRTMKSVNASNYGLSPDRQFVYLESDYSKLWRYSYTATYYIYD 134 L+ E G + + T + +A + SPD Q + ++ A + Sbjct: 61 ---LWLSEGGAARPLTHAETGRGDSAPRW--SPDGQNLAFVRSAGEV-----KAALMLLP 110 Query: 135 LSNGEFVRGNELPRPIQYLCWSPVGSKLAYVYQNNIYLKQRPGDPPFQITFNGRENKIFN 194 L GE R + WSP G +A+ + K+ +T R N Sbjct: 111 LKGGEARRVTHFKNGVSGPQWSPDGRFIAFTTTADTEDKRDERGEARVLT---RPVYRAN 167 Query: 195 GIPDWVYEE-------EMLATKYALWWSPN 217 G DW+ E ++ A K W++P Sbjct: 168 G-ADWLPERPAALWLYDVEADKLREWYAPE 196 >5L8S-A nrPDB Length = 604 Score = 223 bits (569), Expect = 2e-58, Method: Composition-based stats. Identities = 86/497 (17%), Positives = 175/497 (35%), Gaps = 44/497 (8%) Query: 272 PAYVGPQEVPVPAMIASSDYYFSWLTWVTDERVCLQWLKRVQNVSVLSICDFREDWQTWD 331 + E ++ + + L V++ +L+ N ++ E+ Sbjct: 135 NTRIRNLETGEDRLLNVGEVSTTELAAVSENEESFVYLRAFANTYIVGFVKMGEETFNIT 194 Query: 332 CPKTQEHIEESRTGWAGGFFVSTPVFSYDAISYYKIFSDKDGYKHIHYIKDTVENAIQIT 391 + H+ PVF+ + Y+ D D ++ T + ++ Sbjct: 195 PDPEKVHVAM------------EPVFTDNETIYFATDYDSDEM-YLAKFDLTSKEFSKVL 241 Query: 392 SGKWEAINI--FRVTQDSLFYSSNEFEEYPGRRNIYRISIGSYPPSKKCVTCHLRKERCQ 449 + E+I + + + + + +YR + + + + + ++ Sbjct: 242 AFDGESIQSVKWDKDNKAFYLITVKGVTDI----LYRYDVATDKVEECSLPVDIIEQ--- 294 Query: 450 YYTASFSDYAKYYALVCYGPGIPISTLHDGRTDQEIKILEENKELENALKNIQLPKEEIK 509 + Y L +P ++ E K L N+ L + +++ P + + Sbjct: 295 ---IQVAKSGNLYILG-RSATVP-HNVYQSSNGVEWKQLTNNRVLGLSPEDMVEP-DIVS 348 Query: 510 KLEVDEITLWYKMILPPQFDRSKKYPLLIQVYGGPCSQSVRSVFAVNWISYLASKEGMVI 569 D + + ++ + + Y + +GGP S R +F + ++ G I Sbjct: 349 YTSFDGMEIE-ALLFKAKPENDNGY-TIFWPHGGPQSAE-RKMFRSMFQCFI--NRGYTI 403 Query: 570 ALVDGRGTAFQGDKLLYAVYRKLGVYEVEDQITAVRKFIEMGFIDEKRIAIWGWSYGGYV 629 + RG+ G V G D I + E GF D ++ + G SYGGY+ Sbjct: 404 FAPNFRGSTGYGSAFTKLVELDWGEGPRLDCIAGIEWLFESGFTDRNKLFLVGGSYGGYM 463 Query: 630 SSLALASGTGLFKCGIAV-APVSSWEYYASV------YTERFMGLPTKDDNLEHYKNSTV 682 + L + F+ + + P + + SV ER++G P +D K+S V Sbjct: 464 ALLLHGRHSDYFRAVVDIFGPSDLFTFINSVPPHWKPIMERWLGDPERDKE-RFIKDSPV 522 Query: 683 MARAEYFRNVDYLLIHGTADDNVHFQNSAQIAKALVNAQVDFQAMWYSDQNHGLSGLSTN 742 + L+I G D V + S QI L D + + D+ HG S Sbjct: 523 TYLDGMVK--PMLVIQGAKDPRVVKEESDQIVAKLKEKGRDVEYLVLEDEGHGFSKKENE 580 Query: 743 -HLYTHMTHFLKQCFSL 758 +Y+ M FL++ +L Sbjct: 581 IKVYSLMLAFLEKHQAL 597 >4HXF-B nrPDB Length = 622 Score = 206 bits (525), Expect = 2e-53, Method: Composition-based stats. Identities = 97/568 (17%), Positives = 190/568 (33%), Gaps = 60/568 (10%) Query: 215 SPNGKFLAYAEFND----TDIPVIAYSYYGDEQYPRTINIPYPKAGAKNPVVRIFIIDTT 270 SP+GK +A+ FN+ I V ++ NI + ++ Sbjct: 67 SPDGKKIAFMRFNEEKKTAQIWVADLKTLSAKKVLEAKNIR----SIEWNQDSRRLLAVG 122 Query: 271 YPAYVGPQEVPVPAMIASSDYYFSWLTWVTDERVCLQWLKRVQNVSVLSICD---FREDW 327 + + + A +F + + E+ W+ + V+ + F Sbjct: 123 FKRREDEDFIFEDDVPA----WFDNMGFFDGEKTTF-WVIDTEGEEVIEQFEKPRFSSGI 177 Query: 328 QTWDCPKTQEHIEESRTGWAGGFFVSTPVFSYDAISYYKIFSDKDGYKHIHYIKDTVENA 387 D + + F Y I +K ++ ++ + + + Sbjct: 178 WHGDSIVVSVPHRDVIPRY----------FKYWDIYLWKDGEEEKLFEKVSFYAIDSDGE 227 Query: 388 IQITSGKWEAINIFRVTQDSLFYSSNEFEEY--PGRRNIYRISIGSYPPSKKCVTCHLRK 445 + GK E + D ++ E + R + + I + Sbjct: 228 RILLYGKPE--KKYVSEHDKIYIYDGEVKGILDDIDREVAQAKIRNGKVYFTLFEEGSVN 285 Query: 446 ERCQYYTASFSDYAKYYALVCYGPGIPISTLHDGRTDQEIKILEE--------NKELENA 497 K++ + I E+ + + N + Sbjct: 286 LYLWDGEVREIAKGKHWIMGFDADERLIYLKETATRPAELYLWDGEERQLTDYNGLIFKK 345 Query: 498 LKNIQLPKEEIKKLEVDEITLWYKMILPPQFDRSKKYPLLIQVYGGPCSQSVRSVFAVNW 557 LK + K +++ E+ WY + P+ +K P+++ V+GGP + + + Sbjct: 346 LKTFEPRHFRFKSIDL-ELDGWY---IKPEIKEGEKAPVIVFVHGGP--KGMYGYYFKYE 399 Query: 558 ISYLASKEGMVIALVDGRGTAFQGDKLLYAVYRKLGVYEVEDQITAVRKFIEM-GFIDEK 616 + +ASK G I V+ RG+ + V + G+ + +D + + +F+ + D + Sbjct: 400 MQLMASK-GYYIVYVNPRGSNGYSEDFALRVLERTGLEDFQDILNGIEEFLRLEPQADRE 458 Query: 617 RIAIWGWSYGGYVSSLALASGTGLFKCGIAVAPVSSWEYYASVYTERFMGL----PTKDD 672 RI I G SYGGY+++ AL + LFK GI+ +S W + Y +GL D Sbjct: 459 RIGITGISYGGYMTNWALTQ-SDLFKAGISENGISYWL---TSYAFSDIGLWFDKEVIGD 514 Query: 673 NLEHYKNSTVMARAEYFRNV--DYLLIHGTADDNVHFQNSAQIAKALVNAQVDFQAMWYS 730 N +N ++ Y +NV LLIH D S L + + + Sbjct: 515 NPLENENYRKLSPLFYAKNVKAPLLLIHSLEDYRCPLDQSLMFYHVLKDLGKEVYIAIFK 574 Query: 731 D--QNHGL--SGLSTNHLYTHMTHFLKQ 754 H + S Y F ++ Sbjct: 575 KGAHGHSIRGSPRHRMKRYKLFMEFFER 602 >3AZQ-A nrPDB Length = 662 Score = 188 bits (477), Expect = 8e-48, Method: Composition-based stats. Identities = 58/257 (22%), Positives = 113/257 (43%), Gaps = 16/257 (6%) Query: 496 NALKNIQLPKEEIKKLEVDEITLWYKMILPPQ---FDR--SKKYPLLIQVYGGPCSQSVR 550 + + P+ +I+ + + I PP F + P ++ +GGP S+ V Sbjct: 381 DPVDPAYYPEPQIRTFTAPDGREIHAHIYPPHSPDFTGPADELPPYVVMAHGGPTSR-VP 439 Query: 551 SVFAVNWISYLASKEGMVIALVDGRGTAFQGDKLLYAVYRKLGVYEVEDQITAVRKFIEM 610 +V ++ ++Y S+ G+ +A V+ G+ G + + GV +VED E Sbjct: 440 AVLDLD-VAYFTSR-GIGVADVNYGGSTGYGRAYRERLRGRWGVVDVEDCAAVATALAEE 497 Query: 611 GFIDEKRIAIWGWSYGGYVSSLALASGTGLFKCGIAVAPVSSWEYYASVYTE----RFMG 666 G D R+A+ G + GG+ ++ +L S T ++ CG + PV +A T R++ Sbjct: 498 GTADRARLAVRGGAAGGWTAASSLVS-TDVYACGTVLYPVLDLLGWADGGTHDFESRYLD 556 Query: 667 --LPTKDDNLEHYKNSTVMARAEYFRNVDYLLIHGTADDNVHFQNSAQIAKALVNAQVDF 724 + + ++ E Y++ + RA+ R V +LL+ G D + + +A+ V Sbjct: 557 FLIGSFEEFPERYRDRAPLTRADRVR-VPFLLLQGLEDPVCPPEQCDRFLEAVAGCGVPH 615 Query: 725 QAMWYSDQNHGLSGLST 741 + + + HG T Sbjct: 616 AYLSFEGEGHGFRRKET 632 >3O4I-A nrPDB Length = 582 Score = 164 bits (414), Expect = 2e-40, Method: Composition-based stats. Identities = 61/277 (22%), Positives = 107/277 (38%), Gaps = 30/277 (10%) Query: 486 KILEENKELENALKNIQLPKEE-----IKKLEVDEITLWYKMILPPQFDRSK--KY---- 534 K++ + L + + LP E ++ +++ FD S+ Y Sbjct: 294 KLVTSHTSLSTPPRIVSLPSGEPLLEGGLPEDLRRSIAGSRLVWVESFDGSRVPTYVLES 353 Query: 535 -------PLLIQVYGGPCSQSVRSVFAVNWISYLAS--KEGMVIALVDGRGTAFQGDKLL 585 P ++ V+GGP ++ S W ++ AS G + + + RG+ G++ Sbjct: 354 GRAPTPGPTVVLVHGGPFAEDSDS-----WDTFAASLAAAGFHVVMPNYRGSTGYGEEWR 408 Query: 586 YAVYRKLGVYEVEDQITAVRKFIEMGFIDEKRIAIWGWSYGGYVSSLALASGTGLFKCGI 645 + E+ED A R E G E + I G+SYGGY++ AL GLFK G+ Sbjct: 409 LKIIGDPCGGELEDVSAAARWARESGLASE--LYIMGYSYGGYMTLCALTMKPGLFKAGV 466 Query: 646 AVAPVSSWE--YYASVYTERFMGLPTKDDNLEHYKNSTVMARAEYFRNVDYLLIHGTADD 703 A A V WE Y S R + E ++ + + + + LIH Sbjct: 467 AGASVVDWEEMYELSDAAFRNFIEQLTGGSREIMRSRSPINHVDRIK-EPLALIHPQNAS 525 Query: 704 NVHFQNSAQIAKALVNAQVDFQAMWYSDQNHGLSGLS 740 + ++ L+ F+A D H ++ + Sbjct: 526 RTPLKPLLRLMGELLARGKTFEAHIIPDAGHAINTME 562 >5UW6-A nrPDB Length = 750 Score = 157 bits (396), Expect = 2e-38, Method: Composition-based stats. Identities = 49/253 (19%), Positives = 88/253 (34%), Gaps = 29/253 (11%) Query: 493 ELENALKNIQLPKEEIKKLEVDEITLWYKMILPPQFDRSKKYPLLIQVYGG-------PC 545 +L+N +++ +E + + D K + P D +K P+ I G PC Sbjct: 445 DLKNDPTQLKIFRESVVP-DFDRSEFEVKQVFVPSKDGTK-IPIFIAARKGISLDGSHPC 502 Query: 546 SQSVRSVFAVNWISYLASKE-------GMVIALVDGRGTAFQGDKLLYAVYRKLGVYEVE 598 F +N + ++ G V L + RG G++ A +R + Sbjct: 503 EMHGYGGFGINMMPTFSASRIVFLKHLGGVFCLANIRGGGEYGEEWHKAGFRDKKQNVFD 562 Query: 599 DQITAVRKFIEMGFIDEKRIAIWGWSYGGYVSSLALASGTGLFKCGIAVAPVSS-WEYYA 657 D I+A I G+ +R+AI G S GG + + + LF C A V ++ Sbjct: 563 DFISAAEYLISSGYTKARRVAIEGGSNGGLLVAACINQRPDLFGCAEANCGVMDMLRFHK 622 Query: 658 SVYTERFMGLPTKDDNLEHYKNSTVMARAEYFRN------------VDYLLIHGTADDNV 705 + G D E +K + R +++ DD V Sbjct: 623 FTLGYLWTGDYGCSDKEEEFKWLIKYSPIHNVRRPWEQPGNEETQYPATMILTADHDDRV 682 Query: 706 HFQNSAQIAKALV 718 +S ++ + Sbjct: 683 VPLHSFKLLATMQ 695 >4AMY-A nrPDB Length = 710 Score = 121 bits (302), Expect = 2e-27, Method: Composition-based stats. Identities = 70/476 (14%), Positives = 143/476 (30%), Gaps = 69/476 (14%) Query: 306 LQWLKRVQNVSVLSICDFREDWQTWDCPKTQEHIEESRTGWAGGFFVST-----PVFSYD 360 L+W+K + N D+ + T KT H R V ++ Sbjct: 277 LKWVKLIDNFE--GEYDYVTNEGTVFTFKTNRHSPNYRLINIDFTDPEESKWKVLVPEHE 334 Query: 361 AISYYKIFSDKDGYKHIHYIKDTVENAIQITSGKWEAINIFRVTQDSLFYSSNEFEEYPG 420 + + + + Y+ D + IF + S+ S + ++ Sbjct: 335 KDVLEWVACVRSNFLVLCYLHDVKNTLQLHDLATGALLKIFPLEVGSVVGYSGQKKDT-- 392 Query: 421 RRNIYRISIGSYPPSKKCVTCHLRKERCQYYTASFSDYAKYYALVCYGPGIPISTLHDGR 480 E +T+ S Y+ + + Sbjct: 393 -------------------------EIFYQFTSFLSPGIIYHCDL-------------TK 414 Query: 481 TDQEIKILEENKELENALKNIQLPKEEIKKLEVDEITLWYKMILPPQFDRSKKYPLLIQV 540 + E ++ E + Q +I D + ++ +P + Sbjct: 415 EELEPRVFREVTVKGIDASDYQ--TVQIFYPSKDGTKIPMFIVHKKGIKLDGSHPAFLYG 472 Query: 541 YGGPCSQSVRSVFAVNWISYLASKEGMVIALVDGRGTAFQGDKLLYAVYRKLGVYEVEDQ 600 YGG + S+ ++V+ + ++ G V+A+ + RG G+ +D Sbjct: 473 YGG-FNISITPNYSVSRLIFVRHM-GGVLAVANIRGGGEYGETWHKGGILANKQNCFDDF 530 Query: 601 ITAVRKFIEMGFIDEKRIAIWGWSYGGYVSSLALASGTGLFKCGIAVAPVSS-WEYYASV 659 A I+ G+ KR+ I G S GG + + LF C IA V +++ Sbjct: 531 QCAAEYLIKEGYTSPKRLTINGGSNGGLLVATCANQRPDLFGCVIAQVGVMDMLKFHKYT 590 Query: 660 YTERFMGLPTKDDNLEHYK---NSTVMAR-----AEYFRNVDYLLIHGTADDNVHFQNSA 711 + D+ +H++ + + A+ + LL+ DD V +S Sbjct: 591 IGHAWTTDYGCSDSKQHFEWLIKYSPLHNVKLPEADDIQYPSMLLLTADHDDRVVPLHSL 650 Query: 712 QIAKALV-------NAQVDFQAMWYSDQNHGLSGLSTNHLYTH--MTHFLKQCFSL 758 + L + HG + + M F+ +C ++ Sbjct: 651 KFIATLQYIVGRSRKQNNPLLIHVDTKAGHGAGKPTAKVIEEVSDMFAFIARCLNI 706 >1YR2-A nrPDB Length = 741 Score = 119 bits (298), Expect = 4e-27, Method: Composition-based stats. Identities = 51/299 (17%), Positives = 86/299 (28%), Gaps = 16/299 (5%) Query: 457 DYAKYYALVCYGPGIPISTLHDGRTDQEIKILEENKELENALKNIQLPKEEIKKLEVDEI 516 ++ L P + L + E L + ++ E++ D Sbjct: 416 PGDRHAYLSFSSFTQPATVLALDPATAKTTPWE-PVHLTFDPADFRV--EQVFYPSKDGT 472 Query: 517 TLWYKMILPPQFDRSKKYPLLIQVYGGPCSQSVRSVFAVNWISYLASKEGMVIALVDGRG 576 + ++ P L+ YGG F+ +++++ S G AL + RG Sbjct: 473 KVPMFIVRRKDAKG--PLPTLLYGYGGFNVAL-TPWFSAGFMTWIDS--GGAFALANLRG 527 Query: 577 TAFQGDKLLYAVYRKLGVYEVEDQITAVRKFIEMGFIDEKRIAIWGWSYGGYVSSLALAS 636 GD A R +D I A I G +AI G S GG + Sbjct: 528 GGEYGDAWHDAGRRDKKQNVFDDFIAAGEWLIANGVTPRHGLAIEGGSNGGLLIGAVTNQ 587 Query: 637 GTGLFKCGIAVAPVSSWEYYASVYTERF----MGLPTKDDNLEHYKNSTVMARA-EYFRN 691 LF V + R+ G P K+ + + + Sbjct: 588 RPDLFAAASPAVGVMDMLRFDQFTAGRYWVDDYGYPEKEADWRVLRRYSPYHNVRSGVDY 647 Query: 692 VDYLLIHGTADDNVHFQNSAQIAKALVNAQV---DFQAMWYSDQNHGLSGLSTNHLYTH 747 L+ DD V +S + AL A + + HG + Sbjct: 648 PAILVTTADTDDRVVPGHSFKYTAALQTAAIGPKPHLIRIETRAGHGSGKPIDKQIEET 706 >2BKL-A nrPDB Length = 695 Score = 119 bits (297), Expect = 6e-27, Method: Composition-based stats. Identities = 51/318 (16%), Positives = 105/318 (33%), Gaps = 18/318 (5%) Query: 426 RISIGSYPPSKKCVTCHLRKERCQYYTASFSDYAKYYALVCYGPGIPISTLHDGRTDQEI 485 R++ P + + D YY + I E+ Sbjct: 345 RVATLKGKPVRTVQLPGVGAASNLMGLEDLDD--AYYVFTSFTTPRQIYKTSVSTGKSEL 402 Query: 486 KILEENKELENALKNIQLPKEEIKKLEVDEITLWYKMILPPQFDRSKKYPLLIQVYGGPC 545 +++ + Q E++ D + ++ R P L+ YGG Sbjct: 403 W-----AKVDVPMNPEQYQVEQVFYASKDGTKVPMFVVHRKDLKRDGNAPTLLYGYGG-F 456 Query: 546 SQSVRSVFAVNWISYLASKEGMVIALVDGRGTAFQGDKLLYAVYRKLGVYEVEDQITAVR 605 + ++ + F + + +L + G V A+ + RG G A +D A Sbjct: 457 NVNMEANFRSSILPWLDA--GGVYAVANLRGGGEYGKAWHDAGRLDKKQNVFDDFHAAAE 514 Query: 606 KFIEMGFIDEKRIAIWGWSYGGYVSSLALASGTGLFKCGIAVAPVSSWEYYASVYTER-F 664 ++ + KR+AI+G S GG + A+ L+ + P+ Y + R + Sbjct: 515 YLVQQKYTQPKRLAIYGGSNGGLLVGAAMTQRPELYGAVVCAVPLLDMVRYHLFGSGRTW 574 Query: 665 MGLPTKDDNLEHYKNSTVMARAEYFRNV----DYLLIHGTADDNVHFQNSAQIAKALVNA 720 + + E +K + + R L++ DD V ++ + A+ N+ Sbjct: 575 IPEYGTAEKPEDFKTLHAYSPYHHVRPDVRYPALLMMAADHDDRVDPMHARKFVAAVQNS 634 Query: 721 QVDFQ---AMWYSDQNHG 735 + ++ HG Sbjct: 635 PGNPATALLRIEANAGHG 652 >5T88-A nrPDB Length = 616 Score = 114 bits (285), Expect = 1e-25, Method: Composition-based stats. Identities = 51/259 (19%), Positives = 93/259 (35%), Gaps = 19/259 (7%) Query: 506 EEIKKLEVDEITLWYKMILPPQFDRSKKYPLLIQVYGGPCSQSVRSVFAVNWISYLASKE 565 EE D + Y ++ + D + + + YGG + ++ +F I +L K Sbjct: 370 EEDFATSKDGTKVHYFIVK-GERDEKRAW---VFGYGG-FNIALTPMFFPQVIPFL--KR 422 Query: 566 GMVIALVDGRGTAFQGDKLLYAVYRKLGVYEVEDQITAVRKFIEMGFIDEKRIAIWGWSY 625 G + + RG + G++ A R+ +D I + K + G+ ++A WG S Sbjct: 423 GGTFIMANLRGGSEYGEEWHRAGMRENKQNVFDDFIAVLEKLKKEGY----KVAAWGRSN 478 Query: 626 GGYVSSLALASGTGLFKCGIAVAPVSSW-----EYYASVYTERFMGLPTKDDNLEHYKNS 680 GG + S L + + PV Y SV+ + G P + E Sbjct: 479 GGLLVSATLTQRPDVMDSALIGYPVIDMLRFHKLYIGSVWIPEY-GNPEDPKDREFLLKY 537 Query: 681 TVMARAE-YFRNVDYLLIHGTADDNVHFQNSAQIAKALVNAQVDFQAMWYSDQNH-GLSG 738 + + + L+ G DD VH ++ + L + H G S Sbjct: 538 SPYHNVDPKKKYPPTLIYTGLHDDRVHPAHALKFFMKLKEIGAPVYLRVETKSGHMGASP 597 Query: 739 LSTNHLYTHMTHFLKQCFS 757 + T + F+ + S Sbjct: 598 ETRARELTDLLAFVLKTLS 616 >3MUN-A nrPDB Length = 693 Score = 108 bits (269), Expect = 1e-23, Method: Composition-based stats. Identities = 72/514 (14%), Positives = 143/514 (27%), Gaps = 60/514 (11%) Query: 273 AYVGPQEVPVPAMIASSDYYFSWLTWVTDERVCLQWLKRVQNVSVLSICDFREDWQTWDC 332 ++ E P D FS ++W+ +E + + Sbjct: 157 IHLMDVESKQPLETPLKDVKFSGISWLGNEGFFYS------SYDKPDGSELSARTDQHKV 210 Query: 333 PKTQEHIEESRTGWAGGFFVSTPV------FSYDAISYYKIFSDKDGYKHIHYIKDTVEN 386 + + G + + D ++ ++ + EN Sbjct: 211 YFHRLGTAQEDDRLVFGAIPAQHHRYVGATVTEDQRFLLISAANSTSGNRLYVKDLSQEN 270 Query: 387 AIQIT-SGKWEAI-NIFRVTQDSLFYSSNEFEEYPGRRNIYRISIGSYPPSKKCVTCHLR 444 A +T G +A ++ +L+ +N + P RR + + P + + R Sbjct: 271 APLLTVQGDLDADVSLVDNKGSTLYLLTN--RDAPNRRLVTVDAANPGPAHWRDLIPE-R 327 Query: 445 KERCQYYTASFSDYAKYYALV--------CYGPGIPISTLHDGRTDQEIKILEENKELEN 496 ++ ++ S +A+Y G + L + + L Sbjct: 328 QQVLTVHSGSGYLFAEYMVDATARVEQFDYEGKRVREVALPGLGSVSGFNGYWWDPALYF 387 Query: 497 ALKNIQLPKEEIKKLEVDEITLWYKM----ILPPQF---------DRSKKYPLLIQVYGG 543 +N P + Y+ P + + PL+I G Sbjct: 388 GFENYAQPPTLYRFEPKSGAISLYRASAAPFKPEDYVSEQRFYQSKDGTRVPLIISYRKG 447 Query: 544 -------PCSQSVRSVFAVNWISYLASK------EGMVIALVDGRGTAFQGDKLLYAVYR 590 P F V+ + G V A+ + RG G A + Sbjct: 448 LKLDGSNPTILYGYGGFDVSLTPSFSVSVANWLDLGGVYAVANLRGGGEYGQAWHLAGTQ 507 Query: 591 KLGVYEVEDQITAVRKFIEMGFIDEKRIAIWGWSYGGYVSSLALASGTGLFKCGIAVAPV 650 + +D I A G+ R+AI G S GG + + L + + V Sbjct: 508 QNKQNVFDDFIAAAEYLKAEGYTRTDRLAIRGGSNGGLLVGAVMTQRPDLMRVALPAVGV 567 Query: 651 SSWEYY-----ASVYTERFMGLPTKDDNLEHYKNSTVMARAE-YFRNVDYLLIHGTADDN 704 Y + + + + ++ K + + ++ DD Sbjct: 568 LDMLRYHTFTAGTGWAYDYGTSADSEAMFDYLKGYSPLHNVRPGVSYPSTMVTTADHDDR 627 Query: 705 VHFQNSAQIAKALV--NAQVDFQAMWYS-DQNHG 735 V +S + A L NA Q + + HG Sbjct: 628 VVPAHSFKFAATLQADNAGPHPQLIRIETNAGHG 661 >4HVT-A nrPDB Length = 711 Score = 101 bits (252), Expect = 9e-22, Method: Composition-based stats. Identities = 53/315 (16%), Positives = 97/315 (30%), Gaps = 16/315 (5%) Query: 458 YAKYYALVCYGPGIPISTLHDGRTDQEIKILEENKELENALKNIQLPKEEIKKLE----- 512 A + + T+ + I + + EL+ K + E LE Sbjct: 396 NAIFGMSSYEEEEEALITIENSIVPPTIYLWVKTHELKIIRKALYSFDSENYVLEQKEAT 455 Query: 513 -VDEITLWYKMILPPQFDRSKKYPLLIQVYGGPCSQSVRSVFAVNWISYLASKEGMVIAL 571 D + + Y ++ K P L++ YGG Q + + + + + K V L Sbjct: 456 SFDGVKIPYFLVYKKGIKFDGKNPTLLEAYGG--FQVINAPYFSRIKNEVWVKNAGVSVL 513 Query: 572 VDGRGTAFQGDKLLYAVYRKLGVYEVEDQITAVRKFIEMGFIDEKRIAIWGWSYGGYVSS 631 + RG G + + D + I+ + + I G S GG + S Sbjct: 514 ANIRGGGEFGPEWHKSAQGIKRQTAFNDFFAVSEELIKQNITSPEYLGIKGGSNGGLLVS 573 Query: 632 LALASGTGLFKCGIAVAPVSSWEYY-ASVYTERFM---GLPTKDDNLEHYKNSTVMARAE 687 +A+ LF P+ Y ++ G P ++L H K + Sbjct: 574 VAMTQRPELFGAVACEVPILDMIRYKEFGAGHSWVTEYGDPEIPNDLLHIKKYAPLENLS 633 Query: 688 YFRNVDYLLI-HGTADDNVHFQNSAQIAKALVNA-QVDFQAMWYSDQNHGLSG--LSTNH 743 + +LI D VH + L + D HG + + Sbjct: 634 LTQKYPTVLITDSVLDQRVHPWHGRIFEYVLAQNPNTKTYFLESKDSGHGSGSDLKESAN 693 Query: 744 LYTHMTHFLKQCFSL 758 + ++ F L Sbjct: 694 YFINLYTFFANALKL 708 >5N4B-A nrPDB Length = 731 Score = 97.6 bits (241), Expect = 2e-20, Method: Composition-based stats. Identities = 38/263 (14%), Positives = 85/263 (32%), Gaps = 31/263 (11%) Query: 507 EIKKLEVDEITLWYKMILPPQFDRSKKYPLLIQVYG-------GPCSQSVRSVFAVNWIS 559 E+ + + +WY + K P+ I + Q FA + Sbjct: 453 ELDPDDFESTQVWY------ESKDGTKIPMFIVRHKSTKFDGTAAAIQYGYGGFATSADP 506 Query: 560 YLA-------SKEGMVIALVDGRGTAFQGDKLLYAVYRKLGVYEVEDQITAVRKFIEMGF 612 + + G + A+ RG G++ R+ V +D I A + ++ + Sbjct: 507 FFSPIILTFLQTYGAIFAVPSIRGGGEFGEEWHKGGRRETKVNTFDDFIAAAQFLVKNKY 566 Query: 613 IDEKRIAIWGWSYGGYVSSLALASGT-GLFKCGIAVAPVSS-WEYYASVYTERFMGLPTK 670 ++AI G + GG + ++ G F + V+ +++ + ++ Sbjct: 567 AAPGKVAINGAANGGLLVMGSIVRAPEGTFGAAVPEGGVADLLKFHKFTGGQAWISEYGN 626 Query: 671 DDNLEHYKNSTVMARAEYFRNVD----YLLIHGTADDNVHFQNSAQIAKALVNA--QVDF 724 E + ++ R L+ D V +S + L + Q Sbjct: 627 PSIPEEFDYIYPLSPVHNVRTDKVMPATLITVNIGDGRVVPMHSFKFIATLQHNVPQNPH 686 Query: 725 QAMWYSDQ---NHGLSGLSTNHL 744 + D+ HG+ + ++ Sbjct: 687 PLLIKIDKSWLGHGMGKPTDKNV 709 >2XE4-A nrPDB Length = 751 Score = 91.0 bits (224), Expect = 2e-18, Method: Composition-based stats. Identities = 51/301 (16%), Positives = 94/301 (31%), Gaps = 26/301 (8%) Query: 462 YALVCYGPGIPISTLHDGRTDQEIKILEENKELENALKNIQLPKEEIKKLEVDEITLWYK 521 + + P +T D + + +E+ E D+ + Sbjct: 438 FRMEYSSLATP-NTWFDVSPQDHSRTAVKVREVGGGFDAANYKVERRFATAPDQTKIPLS 496 Query: 522 MILPPQFDRSKKYPLLIQVYGGPCSQSVRSVFAVNWISYLASKEGMVIALVDGRGTAFQG 581 ++ D S+ P ++ YG S+ F++ + Y GM+ A+ RG + G Sbjct: 497 VVYHKDLDMSQPQPCMLYGYGS-YGLSMDPQFSIQHLPY--CDRGMIFAIAHIRGGSELG 553 Query: 582 DKLLYAVYRKL-GVYEVEDQITAVRKFIEMGFIDEKRIAIWGWSYGGYVSSLALASGTGL 640 + L D I A + ++A G S GG + L L Sbjct: 554 RAWYEIGAKYLTKRNTFSDFIAAAEFLVNAKLTTPSQLACEGRSAGGLLMGAVLNMRPDL 613 Query: 641 FKCGIAVAPVSSWEYYASVYTERFMGLP----TKDD--NLEHYKNSTVM---ARAEYFRN 691 FK +A P + + T +P ++ N YK M + + R Sbjct: 614 FKVALAGVP-----FVDVMTTMCDPSIPLTTGEWEEWGNPNEYKYYDYMLSYSPMDNVRA 668 Query: 692 VDY--LLIH-GTADDNVHFQNSAQIAKALVNAQVDFQ---AMWYSDQNHGLSGLSTNHLY 745 +Y +++ G D V + A+ L + D + H S + Sbjct: 669 QEYPNIMVQCGLHDPRVAYWEPAKWVSKLRECKTDNNEILLNIDMESGH-FSAKDRYKFW 727 Query: 746 T 746 Sbjct: 728 K 728 >3WYD-A nrPDB Length = 228 Score = 83.7 bits (205), Expect = 3e-16, Method: Composition-based stats. Identities = 45/222 (20%), Positives = 81/222 (36%), Gaps = 42/222 (18%) Query: 514 DEITLWYKMILPPQFDRSKKYPLLIQVYG-GPCSQSVRSVFAVNWISYLASKEGMVIALV 572 + Y++ +P +D +K +PL+I ++G G S + A G ++A Sbjct: 17 RGSHMPYRLYVPTTYDGTKAFPLVIALHGMGGDENSYFDSYQRGAFMIEAENRGYIVACP 76 Query: 573 DGRGTAFQGDKLLYAVYRKLGVYEVEDQITAVRKFIEMGFIDEKRIAIWGWSYGGYVSSL 632 GR A ++Y +V D I VR+ + ID RI + G S GGY + Sbjct: 77 KGRQPA--------SMYVGPAERDVMDVIAEVRRDYK---IDPDRIYMTGHSMGGYGTWS 125 Query: 633 ALASGTGLFKCGIAVAPVSSWEYYASVYTERFMGLPTKDDNLEHYKNSTVMARAEYFRNV 692 + +F A+APV+ N + + + Sbjct: 126 IAMNHPDVFA---ALAPVA------------------GGGNPLG--MANIAH-------I 155 Query: 693 DYLLIHGTADDNVHFQNSAQIAKALVNAQVDFQAMWYSDQNH 734 L++HG D V + S + +A + + + +H Sbjct: 156 PQLVVHGDNDKTVPVERSRVMVEAAKKHGTEIKYIEIPGGDH 197 >4BP8-A nrPDB Length = 715 Score = 83.3 bits (204), Expect = 3e-16, Method: Composition-based stats. Identities = 59/349 (16%), Positives = 108/349 (30%), Gaps = 34/349 (9%) Query: 426 RISIGSYPPSKKCVTCHLRKERCQYYTASFSDYAKYYALVCYGPGIPISTLHDGRTDQEI 485 ++ + T H+ + + Y AS L P + +D Sbjct: 374 SATLKELHFDEPVFTAHVVCSQMKTYDASL------LRLRYSSMTTP-TVWYDEDVLSGE 426 Query: 486 KILEENKELENALKNIQLPKEEIKKLEVDEITLWYKMILPPQFDRSKKYPLLIQVYGGPC 545 + + + +++ ++ D + ++ D K P ++ YG Sbjct: 427 RKVVKARKVGGGFESKNYVCRRELATAPDGTKVPISLVYDTSIDLKKPNPTMLYGYGS-Y 485 Query: 546 SQSVRSVFAVNWISYLASKEGMVIALVDGRGTAFQGDKLLYAVYRKL-GVYEVEDQITAV 604 + F ++ Y+ GM+ A+ RG G + L D I Sbjct: 486 GICIEPEFNSRFLPYV--DRGMIYAIAHVRGGGEMGRTWYEVGGKYLTKRNTFMDFIACA 543 Query: 605 RKFIEMGFIDEKRIAIWGWSYGGYVSSLALASGTGLFKCGIAVAPVSSWEYYASVYTERF 664 I G +++ G S GG + L LF +A P + + T Sbjct: 544 EHLISSGLTTPAQLSCEGRSAGGLLVGAVLNMRPDLFHVALAGVP-----FVDVMTTMCD 598 Query: 665 MGLP----TKDD--NLEHYKNSTVM---ARAEYFRNVDY--LLIH-GTADDNVHFQNSAQ 712 +P ++ N YK M + + R DY L+I G D V + A+ Sbjct: 599 PSIPLTTGEWEEWGNPNEYKFFDYMNSYSPIDNVRAQDYPHLMIQAGLHDPRVAYWEPAK 658 Query: 713 IAKALVNAQVDFQAMWYS---DQNHGLSGLSTNHLYTHMTHFLKQCFSL 758 A L + D + + H S + ++Q F L Sbjct: 659 WASKLRELKTDSNEVLLKMDLESGH-FSASDRYKYLR--ENAIQQAFVL 704 >5TXC-A nrPDB Length = 705 Score = 76.0 bits (185), Expect = 5e-14, Method: Composition-based stats. Identities = 104/646 (16%), Positives = 189/646 (29%), Gaps = 93/646 (14%) Query: 153 LCWSPVGSKLAY-VYQNNIYLKQRPGDPPFQITFNGRENKI---------FNGIPDWVYE 202 L SP G +A+ V Q + + T +G + I F IP W Y Sbjct: 61 LSLSPDGRYVAFQVRQADPVTNLNVFRMVVKAT-DGATDAIDVDVGGEYLFWTIPSWGYA 119 Query: 203 EEMLATKYALW---WSPNGKFLAYAEFNDTDIPVIAYSYYGDEQYPRTINIPYPKAGAKN 259 + WSP+G LAY + + V S G+ P I Y + Sbjct: 120 RNAPSGANLTIQPRWSPSGTHLAYLRQDQGRVRVWRASVKGEGASP-VIEDAYDIEDVQW 178 Query: 260 PVVRIFIIDTTYPAYVGPQEVPVPAMIASSDYYFSWLTWVTDER---VCLQWLKRVQNVS 316 I E+ WV DER + + ++ +S Sbjct: 179 LDDNTLIYSGRPGFVEAEAEIEREG----------RRGWVYDERFHPLTGARPRVLEPIS 228 Query: 317 VL-SICDFREDWQTWDCPKTQEHIEESRT---GWAGGFFVSTPVFSYDAISYYKIFSDKD 372 ++ + D + + P + E G S I+ + Sbjct: 229 IVYQVLDLKTGTRRAATPTEVARLREKPDPLRAMVGRTTFSVSRTDPQNINAPTTLVARR 288 Query: 373 GYKHIHYIKDTVENAIQITSGKWEAINIFRVTQDSLFYSSNEFEEYPGRRNIYRISIGSY 432 G ++ E IT ++ ++ Y +YR+ + Sbjct: 289 GEGE--PVRCDEEACQNIT-------RMWGDETANVLYFLRREGWASNEMALYRMPADAL 339 Query: 433 PPSKKCVTCHLRKERCQYYTASFSDYAKYYALVCYGPGIP--ISTLHDGRTDQEIKILEE 490 P + L + C+ AK P + TL+ + Sbjct: 340 KPVRIWHATGLL-QGCER-------QAKRLICAQESALQPRRLVTLNLTSGQ-----MSP 386 Query: 491 NKELENALKNIQLPKEEIKKL-EVDEITLWYKMILPPQFDRSKKYPLLIQVYGGPCSQSV 549 + L +LPK E L + I ++ ++LPP + + PL+I Y S+ Sbjct: 387 LYDPNPDLSRYRLPKVERLTLRNRNGIEVFSDLVLPPDYQLGTRLPLVIVQYS---SRGF 443 Query: 550 RSVFAVNWISYL-ASKEGMVIALV-DGRGTAFQGDKLLYAV----------YRKLGVYE- 596 + L + G + R A + + + + Sbjct: 444 LRGGTGDENPILPLATAGFAVLSFHSPRSEASY-QRFTSPIAQSKAEYSNWRNRWNILHT 502 Query: 597 VEDQITAVRKFIEMGFIDEKRIAIWGWSYGGYVSSLALASGTGLFKCGIAVAPVSSWEYY 656 +ED I G ID R+ + G S G L + F + + + Sbjct: 503 LEDLI---DDLDRRGVIDPARVGLTGLSDGATTVHFGLI-NSHRFAAAVTSSCCTD---- 554 Query: 657 ASVYTERFMGLPTKDDNLEHYKNSTVMARAEYFRNVDYLLIHGT-ADDNVHFQNSAQIA- 714 +T M P L+ Y T A F +++ + D + Q++ + Sbjct: 555 --SFTASVMNGPRISGALKAYGIETDQADDGPFWAATSFVVNASRLDTPLLIQSADEEYL 612 Query: 715 ------KALVNAQVDFQAMWYSDQNH-GLSGLSTNHLYTHMTHFLK 753 AL A+ + + Y +++H +Y + + Sbjct: 613 GALPGFTALQQARKPVELIIYPNEHHVKWQPAHRLAVYNRTIDWFR 658 >5AOA-A nrPDB Length = 286 Score = 71.4 bits (173), Expect = 1e-12, Method: Composition-based stats. Identities = 43/252 (17%), Positives = 87/252 (34%), Gaps = 27/252 (10%) Query: 501 IQLPKEEIKKLE-VDEITLWYKMILPPQFDRSKKYPLLIQVYGGPCSQSVRSVFAVNWIS 559 ++P E+K + VD + L + P + + + ++ +GG + F Sbjct: 10 PEMPGAEVKVYKKVDNVDLKLYIYKPADWKPADRRSAIVFFFGGGWQSGSPAQFRPQCEY 69 Query: 560 YLASKEGMVIALVDGRGTAFQGDKLLYAVYRKLGVYEVEDQITAVRKFIEMGF---IDEK 616 + + GMV D R + K+ V D +A+R + +D + Sbjct: 70 F--AGRGMVAMAADYRVGSRHNVKVADCV---------ADAKSAIRWVRQHAAELGVDPQ 118 Query: 617 RIAIWGWSYGGYVSSLA-----LASGTGLFKCGIAVAPVSSWEYYASVYTERFMGLPTKD 671 +I G S GG++++ L + + + E + Sbjct: 119 KIVASGGSAGGHLAACTVMVPDLEAPEEDHTISSQANAAILFNPVLILSREGLKDHVPRQ 178 Query: 672 DNLEHYKNS-----TVMARAEYFRNV--DYLLIHGTADDNVHFQNSAQIAKALVNAQVDF 724 D E + ++ + R ++ HGTAD+ V F+ A+A+ A Sbjct: 179 DWEERLRERLGTEPKAVSPYHHIRAGLPPMIIFHGTADNTVPFETIRLFAEAMKKAGNRC 238 Query: 725 QAMWYSDQNHGL 736 + + + HG Sbjct: 239 ELVPFEGAAHGF 250 >3FCY-A nrPDB Length = 346 Score = 64.8 bits (156), Expect = 1e-10, Method: Composition-based stats. Identities = 50/263 (19%), Positives = 85/263 (32%), Gaps = 54/263 (20%) Query: 508 IKKLEVDEITLWYKMILPPQFDRSKKYPLLIQVYGGPCSQSVRSVFAVNWI---SYLASK 564 + V + K I P K+P LI+ +G S + +W +Y+A+ Sbjct: 85 LYFTGVRGARIHAKYIKPKT---EGKHPALIRFHG-------YSSNSGDWNDKLNYVAA- 133 Query: 565 EGMVIALVDGRGTAFQGDKLLYAVYRKL------GVYEVED------------QITAVRK 606 G + +D RG Q + L G+ + D Q+ + Sbjct: 134 -GFTVVAMDVRGQGGQSQDVGGVTGNTLNGHIIRGLDDDADNMLFRHIFLDTAQLAGI-- 190 Query: 607 FIEMGFIDEKRIAIWGWSYGGYVSSLALASGTGLFKCGIAVAP-------VSSWEYYASV 659 + M +DE R+ + G S GG +S A + K ++ P V + + Sbjct: 191 VMNMPEVDEDRVGVMGPSQGGGLSLACAALEPRVRKV-VSEYPFLSDYKRVWDLDLAKNA 249 Query: 660 YTE-----RFMGLPTKDDNLEHYKNS--TVMARAEYFRNVDYLLIHGTADDNVHFQNSAQ 712 Y E R + +N K V A+ + + + G D + Sbjct: 250 YQEITDYFRLFDPRHERENEVFTKLGYIDVKNLAKRIKGDVLMCV-GLMDQVCPP---ST 305 Query: 713 IAKALVNAQVDFQAMWYSDQNHG 735 + A N Q Y D H Sbjct: 306 VFAAYNNIQSKKDIKVYPDYGHE 328 >5JRK-A nrPDB Length = 756 Score = 62.9 bits (151), Expect = 4e-10, Method: Composition-based stats. Identities = 51/280 (18%), Positives = 101/280 (36%), Gaps = 48/280 (17%) Query: 503 LPKEEIKKLEVDEITLWYK--MILPPQFDRSKKYPLLIQVYGGPCSQSVRSVFAVNWISY 560 P + I + V W ++LP + ++P ++ +G FA + Sbjct: 441 EPLQTIARTFVSRDGYWSSGYVLLPRGHRAADRHPAVVVTHGT----DADDRFAEPANQW 496 Query: 561 -----LASKEGMVIALVDGRGTAFQGDKLLYAVYRKL------------------GVYEV 597 L ++ G V+ L++ + Q L+ A++ L GV+ Sbjct: 497 NYPVQLLAERGYVVLLLND-PSPGQSKDLMDAMHAWLRGKGPPDPETVQQKLWLTGVHSF 555 Query: 598 EDQITAVRKFIEMGFIDEKRIAIWGWSYGGYVSSLALASGTGLFKCGIAV-APVSSWEYY 656 ED AV + G ID R+ I G+S G + ++ + + +F+ + Y Sbjct: 556 ED---AVTELAAEGLIDPARVGIAGYSRGSQMVNVTVT-NSKMFRAASSGDGGFLEPAGY 611 Query: 657 ASV---YTERFMGLPTKDDNLEHYKNSTVMARAEYFRNVDYLLIHGTADDNVHFQNSAQI 713 A+ Y + G P DN+E ++ A+ + + + ++ Sbjct: 612 ATGRSSYDAVYGGAP-LSDNIERWRRFAPSLNADKVCAAVLQQVASASPSQI------EL 664 Query: 714 AKALVNAQVDFQAMWYSDQNHGLSGLSTNHLYTHMTHFLK 753 +AL A V Q +Y + H++ T+ L+ Sbjct: 665 FEALRAAGVATQISYYPGAT---AASDETHVFYLTTNRLR 701 >6FKX-A nrPDB Length = 324 Score = 61.0 bits (146), Expect = 2e-09, Method: Composition-based stats. Identities = 45/267 (16%), Positives = 83/267 (31%), Gaps = 44/267 (16%) Query: 513 VDEITLWYKMILPPQFDRSKKYPLLIQVYGGPCSQSVRSVFAVNWISYL-ASKEGMVIAL 571 + + K++ P + +P L+Q +G + + +W S L G +A Sbjct: 68 TGGVRVHAKLLRPVA--PVEPHPALLQFHG-------YTGNSGDWSSRLHYVALGYTVAA 118 Query: 572 VDGRGTAFQG------DKLLYAVYRKLGVYE-----------VEDQITAVRKFIEMGFID 614 +D RG A + A Y G+ + D + + M +D Sbjct: 119 LDCRGQAGLSVGEAPVENWSMASYLLRGIDDDAADNLALRHLFLDTARLAQIVLAMDDVD 178 Query: 615 EKRIAIWGWSYGGYVSSLALASGTGLFKCGIAVAPVS-----SWEYYASVYTERFMGLPT 669 R+A G+S GG ++ A + + V P +WE + Sbjct: 179 PDRVAATGYSQGGGLTLACAALEPRI-RLAAPVYPFLCDFRRAWEMDLEKGPYNEITTYF 237 Query: 670 KDDNLEHYKNSTVMARAEYFRNVDY--------LLIHGTADDNVHFQNSAQIAKALVNAQ 721 + + H + + +R Y L+ AD S Q A Sbjct: 238 RARDPRHLREEEIFSRLGYVDVQHLAPRVRAEVLMTVSLADKICPP--STQF-AAYNKLG 294 Query: 722 VDFQAMWYSDQNHGLSGLSTNHLYTHM 748 Y D H + + ++T + Sbjct: 295 GPKDYRLYPDFAHETLPGTDDAIFTFL 321 >3KSR-A nrPDB Length = 290 Score = 59.1 bits (141), Expect = 6e-09, Method: Composition-based stats. Identities = 45/249 (18%), Positives = 78/249 (31%), Gaps = 34/249 (13%) Query: 510 KLEVDEITLWYKMILPPQFDRSKKYPLLIQVYGGPCSQSVRSVFAVNWISYLASKEGMVI 569 ++ V + L ++ P P ++ V+G SQ S+ A G + Sbjct: 10 EIPVGQDELSGTLLTPTGM------PGVLFVHGWGGSQH-HSLVRARE----AVGLGCIC 58 Query: 570 ALVDGRGTAFQGDKLLYAVYRKLGVYEVEDQITAVRKFIEMGFIDEKRIAIWGWSYGGYV 629 D RG + +V R ++D A + + ++D IA+ G SYGGY+ Sbjct: 59 MTFDLRGHEGY-ASMRQSVTRAQ---NLDDIKAAYDQLASLPYVDAHSIAVVGLSYGGYL 114 Query: 630 SS---------LALASGTGLFKCGIAVAPVSSWEYYASVYTERFMGLPTKDDNLEHYKNS 680 S+ L+K P S + R L DNL Sbjct: 115 SALLTRERPVEWLALRSPALYKDAHWDQPKVSLNADPDLMDYRRRAL-APGDNL------ 167 Query: 681 TVMARAEYFRNVDYLLIHGTADDNVHFQNSAQIAKALVNAQVDFQAMWYSDQNHGLSGLS 740 +A ++ L+ +D + + + + +H LS Sbjct: 168 -ALAACAQYKGDVLLV--EAENDVIVPHPVMRNYADAFTNARSLTSRVIAGADHALSVKE 224 Query: 741 TNHLYTHMT 749 YT Sbjct: 225 HQQEYTRAL 233 >5V5V-A nrPDB Length = 582 Score = 59.1 bits (141), Expect = 7e-09, Method: Composition-based stats. Identities = 49/196 (25%), Positives = 80/196 (40%), Gaps = 23/196 (11%) Query: 469 PGIPISTLHDGRTDQEIKILEENKELENALKNIQLPKEEIKKLEV-DEITLWYKMILPPQ 527 P I + + +N+ + N+ +P E+ + DE TL PP Sbjct: 75 PAIMLPVWF-TDNLEAAATYVQNQSEDCLYLNLYVPTEDGPLTKKRDEATLN-----PPD 128 Query: 528 FD--RSKKYPLLIQVYGGPCSQSVRSVFAVNWISYLASKEGMVIALVDGR-GTAFQGDKL 584 D S K P+++ ++GG + ++F S LA+ +++A ++ R G Sbjct: 129 TDIRDSGKKPVMLFLHGGSYMEGTGNMFDG---SVLAAYGNVIVATLNYRLGVLGFLSTG 185 Query: 585 LYAVYRKLGVYEVEDQITAVRKFIEMGF---IDEKRIAIWGWSYGGYVSSLALASG--TG 639 A G+ DQI A+R E D +RI I+G G +L + S G Sbjct: 186 DQAAKGNYGLL---DQIQALRWLSENIAHFGGDPERITIFGSGAGASCVNLLILSHHSEG 242 Query: 640 LFKCGIA--VAPVSSW 653 LF+ IA +SSW Sbjct: 243 LFQKAIAQSGTAISSW 258 >3FCX-A nrPDB Length = 282 Score = 55.2 bits (131), Expect = 9e-08, Method: Composition-based stats. Identities = 47/288 (16%), Positives = 92/288 (31%), Gaps = 43/288 (14%) Query: 496 NALKNIQLPKEEIKKLEVDEITLWYKM----ILPPQFDRSKKYPLLIQVYGGPCSQSVRS 551 + + + K E D + L KM LPP+ + K P L + G C++ + Sbjct: 4 KQISSNKCFGGLQKVFEHDSVELNCKMKFAVYLPPKAETGK-CPALYWLSGLTCTEQ--N 60 Query: 552 VFAVNWISYLASKEGMVIALVD--GRGTAFQGDK-----------LLYAVYRKLGVYEV- 597 + + AS+ G+V+ D RG +G+ + A Sbjct: 61 FISKSGYHQSASEHGLVVIAPDTSPRGCNIKGEDESWDFGTGAGFYVDATEDPWKTNYRM 120 Query: 598 -EDQITAVRKFIEMGF-IDEKRIAIWGWSYGGYVSSLALASGTGLFKCGIAVAPVSS--W 653 + + I F +D +R++I+G S GG+ + + G +K A AP+ + Sbjct: 121 YSYVTEELPQLINANFPVDPQRMSIFGHSMGGHGALICALKNPGKYKSVSAFAPICNPVL 180 Query: 654 EYYASVYTERFMGLPTKDDNLEHYKNSTVMARAEYFRNVDY--LLIHGTADDNVHFQN-- 709 + ++G + +K + + L+ G D + Sbjct: 181 CPWGKKAFSGYLGT-----DQSKWKAYDATHLVKSYPGSQLDILIDQGKDDQFLLDGQLL 235 Query: 710 SAQIAKALVNAQVDFQAMWYSDQNHGLSGLSTNHLYTHMTHFLKQCFS 757 A ++ D +H Y + F+ Sbjct: 236 PDNFIAACTEKKIPVVFRLQEDYDHS---------YYFIATFITDHIR 274 >1C7J-A nrPDB Length = 489 Score = 54.4 bits (129), Expect = 2e-07, Method: Composition-based stats. Identities = 46/288 (15%), Positives = 96/288 (33%), Gaps = 36/288 (12%) Query: 480 RTDQEIKILEENKELENALKNIQLPKEEIKKLEVDEITLW-------YKMILPPQFDRSK 532 + + ++ E+ L+ P+ L + L Y + P S+ Sbjct: 40 KAPEPPEVWEDV--LDATAYGPVCPQPS-DLLSLSYTELPRQSEDCLYVNVFAPD-TPSQ 95 Query: 533 KYPLLIQVYGGPCSQSVRSVFAVNWISYLASKEGMVIALVDGRGTAF---QGDKLLYAVY 589 P+++ ++GG + S LA++ +++ ++ R F A Sbjct: 96 NLPVMVWIHGGAFY-LGAGSEPLYDGSKLAAQGEVIVVTLNYRLGPFGFMHLSSFDEAYS 154 Query: 590 RKLGVYEVEDQITAVRKFIEMGFI---DEKRIAIWGWSYGGYVSSLALASGT---GLFKC 643 LG+ DQ A++ E D + ++G S GG +S AL + GLF+ Sbjct: 155 DNLGLL---DQAAALKWVRENISAFGGDPDNVTVFGESAGG-MSIAALLAMPAAKGLFQK 210 Query: 644 GI--AVAPVSSWEYYASVYTERFMGL----PTKDDNLEHYKNSTVMARAEYFR-----NV 692 I + A + + A+ F+ + ++ D L ++ A+ R N+ Sbjct: 211 AIMESGASRTMTKEQAASTAAAFLQVLGINESQLDRLHTVAAEDLLKAADQLRIAEKENI 270 Query: 693 DYLLIHGTADDNVHFQNSAQIAKALVNAQVDFQAMWYSDQNHGLSGLS 740 L D + + + + D+ + Sbjct: 271 FQLFFQPALDPKTLPEEPEKSIAEGAASGIPLLIGTTRDEGYLFFTSD 318 >3I6Y-A nrPDB Length = 280 Score = 53.7 bits (127), Expect = 3e-07, Method: Composition-based stats. Identities = 50/259 (19%), Positives = 97/259 (37%), Gaps = 38/259 (14%) Query: 520 YKMILPPQFDRSKKYPLLIQVYGGPCSQSVRSVFAVNWISYLASKEGMVIALVD--GRGT 577 + + LPPQ K P+L + G CS + LA++ G+ I D RG Sbjct: 33 FAIYLPPQASTGAKVPVLYWLSGLTCSDE--NFMQKAGAQRLAAELGIAIVAPDTSPRGE 90 Query: 578 A---------FQGDKL-LYAVYRKLGV-YEVED-QITAVRKFIEMGFIDEKRIAIWGWSY 625 QG + A Y++ D + + + IE F + AI G S Sbjct: 91 GVADDEGYDLGQGAGFYVNATQAPWNRHYQMYDYVVNELPELIESMFPVSDKRAIAGHSM 150 Query: 626 GGYVSSLALASGTGLFKCGIAVAPVSS-----WEYYASVYTERFMGLPTKDDNLEHYKNS 680 GG+ + ++ A +P+++ W +T ++G KD + ++ Sbjct: 151 GGHGALTIALRNPERYQSVSAFSPINNPVNCPWG--QKAFTA-YLG---KDTDTWREYDA 204 Query: 681 TVMARAEYFRNVDYLLIHGTADDNVHFQNSAQIAKALVNAQV-DFQAMWYSDQNHGLSGL 739 +++ RA + V L+ G AD+ + Q ++ +A ++ + + +H Sbjct: 205 SLLMRAAK-QYVPALVDQGEADNFLAEQLKPEVLEAAASSNNYPLELRSHEGYDHS---- 259 Query: 740 STNHLYTHMTHFLKQCFSL 758 Y + F++ Sbjct: 260 -----YYFIASFIEDHLRF 273 >4Q3K-A nrPDB Length = 260 Score = 53.7 bits (127), Expect = 3e-07, Method: Composition-based stats. Identities = 38/209 (18%), Positives = 75/209 (35%), Gaps = 32/209 (15%) Query: 533 KYPLLIQVYGGPCSQSVRSVFAVNWISYLASKEGMVIALVDGRGTAFQGDKLLYAVYRKL 592 K P ++ GG +SYLA +G ++ K +AV+ + Sbjct: 53 KRPAMLIFPGGGYQFCSDREAEPIALSYLA--KGYNAFVL------RYSVK-EHAVFPRP 103 Query: 593 GVYEVEDQITAVRKFIEMGFIDEKRIAIWGWSYGGYVSSLALASGTGLFKCGIAVAPVSS 652 + + ED ++ ++ I+ +IA+ G+S GG++++ G + P Sbjct: 104 -LIDAEDALSYLKDNAHALHINPDKIAVIGFSAGGHLATTLATEGKVRPNAVVLGYP--- 159 Query: 653 WEYYASVYTERFMGLPTKDDNLEHYKNSTVMARAEYFRNVDYLLIHGTADDNVHFQNSAQ 712 A + E++ PT + + + + H DD V + Sbjct: 160 ----ALIRHEKYWNFPTPKVDQ---------------QTPEMFVFHTFEDDLVPLSHPLY 200 Query: 713 IAKALVNAQVDFQAMWYSDQNHGLSGLST 741 I + L A + + + HGLS + Sbjct: 201 IVEELSKANIPVEFHLFKSGVHGLSLGNK 229 >4V2I-A nrPDB Length = 323 Score = 53.3 bits (126), Expect = 4e-07, Method: Composition-based stats. Identities = 45/297 (15%), Positives = 92/297 (30%), Gaps = 37/297 (12%) Query: 465 VCYGPGIPISTLHDGRTDQEIKIL--EENKELENALKNIQLPKEEIKKLEVDEITLWYKM 522 V I L E +++ + ++ ++ K + + Sbjct: 3 VLEPTTQKFINALSASGGPAIYTLTPAEARDVLSGAQSGEIAKPAVDITDTTFAVGPTGA 62 Query: 523 ILPPQFDR---SKKYPLLIQVYGGPCSQSVRSVFAVNWISYLASKEGMVIALVDGRGTAF 579 + + P+++ +G + + L+ + + VD + Sbjct: 63 TKVRIIRPQGNTDRLPVIVYFHGAGWVM-GDTGTHDRLVRELSVRANAALVFVDYERSPE 121 Query: 580 QGDKLLYAVYRKLGVYEVEDQITAVRKFIEMGFIDEKRIAIWGWSYGGYVSS--LALAS- 636 + A+ + V + V + E +D R+AI G S GG +++ LA Sbjct: 122 --ARYPVAIEQDYAVTKY------VAEHSEQLNVDPTRLAIAGDSVGGNMTAVVSLLAQE 173 Query: 637 --GTGLFKCGIAVAPVSSWEYYASVYTE----RFMGLPTKDDNLEHY------KNSTVMA 684 G + + PV+ ++ YTE ++ P D Y + + Sbjct: 174 RGGPDI-TAQVLFYPVTDADFDNGSYTEFANGPWLTKPAMDWFWNQYLPEGIDRTDPKIT 232 Query: 685 RAEYFRNV-----DYLLIHGTADDNVHFQNSAQIAKALVNAQVDFQAMWYSDQNHGL 736 L+I TA+++V A+ L A VD Y+ H Sbjct: 233 PIHATSEQLSGQAPALVI--TAENDVLRDEGEAYARKLSQAGVDVTVTRYNGTIHDF 287 >1K4Y-A nrPDB Length = 534 Score = 52.9 bits (125), Expect = 5e-07, Method: Composition-based stats. Identities = 36/194 (18%), Positives = 68/194 (35%), Gaps = 13/194 (6%) Query: 467 YGPGIPISTLHDGRTDQEIKILEENKELEN-ALKNIQLPKEEIKKLEVDEITLWYKMILP 525 + P P + + + + L + ++E L+ E L+ + P Sbjct: 43 FAPPQPAESWSHVKNTTSYPPMCSQDAVSGHMLSELFTNRKENIPLKFSEDCLYLNIYTP 102 Query: 526 PQFDRSKKYPLLIQVYGGPCSQSVRSVFAVNWISYLASKEGMVIALVDGR-GTAFQGDKL 584 + + P+++ ++GG S + L++ E +V+ + R G Sbjct: 103 ADLTKRGRLPVMVWIHGGGLMVGGASTYDG---LALSAHENVVVVTIQYRLGIWGFFSTG 159 Query: 585 LYAVYRKLGVYEVEDQITAVRKF---IEMGFIDEKRIAIWGWSYGGYVSSLALAS--GTG 639 G DQ+ A+R I D + I+G S GG S+ L S Sbjct: 160 DEHSRGNWGHL---DQVAALRWVQDNIANFGGDPGSVTIFGESAGGQSVSILLLSPLTKN 216 Query: 640 LFKCGIAVAPVSSW 653 LF I+ + V+ Sbjct: 217 LFHRAISESGVALL 230 >6AAE-A nrPDB Length = 317 Score = 52.9 bits (125), Expect = 6e-07, Method: Composition-based stats. Identities = 45/285 (15%), Positives = 80/285 (28%), Gaps = 50/285 (17%) Query: 477 HDGRTDQEIKILEENKELENALKNIQLPKEEIKKLEVDEITLWYKMILPPQFDRSKKYPL 536 EI+ + +N Q+ + E + +D L ++ +P D P Sbjct: 22 FSVANPAEIRAVFDNLA-----APPQVARVENIAISLDGRDLDARLYVPEDADER---PA 73 Query: 537 LIQVYGGPCSQSVRSVFAVNWISYLASKEGMVIALVDGRGTAFQGDKLLYAVYRKLGVYE 596 L+ Y G LA K G + + R Sbjct: 74 LMVYYHGGGWVIGTLDTHDGTCRALAQKSGCAVLSIAYRLAPEYRYP-----------AP 122 Query: 597 VEDQITAVRKFIEMGF---IDEKRIAIWGWSYGGYVSSLALASGTGLFKCG----IAVAP 649 ED A+ + +D R+A+ G S GG +++ + + P Sbjct: 123 AEDCYDALVWAKQNAATLGVDGDRLAVGGDSAGGNLAAAVAIMARDRNGPALRHQLLIYP 182 Query: 650 VSSWEYYASVYTER------------------FMGLPTKDDNLEHYKNSTVMARAEYFRN 691 V+ ++ + Y E ++G ++ + V+ A+ Sbjct: 183 VTDNDFTLASYAENGGGEYYLSTDGMRWFWGHYLGDTAAENAPL----AAVLNVADLSGL 238 Query: 692 VDYLLIHGTADDNVHFQNSAQIAKALVNAQVDFQAMWYSDQNHGL 736 +I D AK L A V A HG Sbjct: 239 APATVITAEYDP--LRDEGIAYAKKLDAAGVPVDAATAPGMIHGF 281 >5XKS-A nrPDB Length = 256 Score = 51.7 bits (122), Expect = 1e-06, Method: Composition-based stats. Identities = 26/218 (11%), Positives = 53/218 (24%), Gaps = 42/218 (19%) Query: 565 EGMVIALVDGRGTAFQGDKLLYAVYRKLGVYEVEDQITAVRKFIEMGFIDEKRIAIWGWS 624 G + +G + + + ++ I + G S Sbjct: 46 AGYTVCGPRLKGHGTHYEDMEKTTCQDW----IDSVEAGYEWLKNRCGT----IFVTGLS 97 Query: 625 YGGYVSSLALASGTGLFKCGI--------------AVAPVSSWEYYASVYTERFMGLPTK 670 GG ++ + CGI A+A V + + Sbjct: 98 MGGTLTLYMAEHHPEI--CGIAPINAAINMPALAGALAGVGDLPRFLDAIGS---DIKKP 152 Query: 671 DDNLEHYKNSTVMA------RAEYFRNV------DYLLIHGTADDNVHFQNSAQIAKALV 718 Y+ + + E + +L D V N+ I + Sbjct: 153 GVKELAYEKTPAASIRQIVQLMERVKTDLHKITCPAILFCSDEDHVVPPDNAPFIYDHIA 212 Query: 719 NAQVDFQAMWYSDQNHGLS-GLSTNHLYTHMTHFLKQC 755 +A D + + D H + + F K+ Sbjct: 213 SA--DKKLVRLPDSYHVATLDNDRQKIIDTSLAFFKKH 248 >3RLI-A nrPDB Length = 270 Score = 50.6 bits (119), Expect = 2e-06, Method: Composition-based stats. Identities = 35/226 (15%), Positives = 66/226 (29%), Gaps = 43/226 (19%) Query: 523 ILPPQFDRSKKYPLL-----IQVYGGPCSQSVRSVFAV--NWISYLA---SKEGMVIALV 572 ++P S++YP+L GP + F + + LA +K G + L Sbjct: 14 LVPRGSHMSEQYPVLSGAEPFYAENGPVGVLLVHGFTGTPHSMRPLAEAYAKAGYTVCLP 73 Query: 573 DGRGTAFQGDKLLYAVYRKLGVYEVEDQITAVRKFIEMGFIDEKRIAIWGWSYGGYVSSL 632 +G + + + V + I + G S GG ++ Sbjct: 74 RLKGHGTHYEDMERTTFHDW----VASVEEGYGWLKQRCQT----IFVTGLSMGGTLTLY 125 Query: 633 ALASGTGLFKCGIA-VAPVSSWEYYASVYT-----ERFM-----GLPTKDDNLEHYKNST 681 + CGI + A+ T R++ L D Y+ + Sbjct: 126 LAEHHPDI--CGIVPINAAVDIPAIAAGMTGGGELPRYLDSIGSDLKNPDVKELAYEKTP 183 Query: 682 VMARAEYFRNV------------DYLLIHGTADDNVHFQNSAQIAK 715 + + R + L+ D V N+ I + Sbjct: 184 TASLLQLARLMAQTKAKLDRIVCPALIFVSDEDHVVPPGNADIIFQ 229 >3BIX-A nrPDB Length = 574 Score = 50.6 bits (119), Expect = 2e-06, Method: Composition-based stats. Identities = 47/209 (22%), Positives = 78/209 (37%), Gaps = 27/209 (12%) Query: 465 VCYGPGIPISTLHDGRTDQEIKILEENKELENALKNIQLPK--------EEIKKLEVDEI 516 P P S D R + + ++ L + LP + E Sbjct: 52 RFQPPEPP-SPWSDIRNATQFAPVCPQNIIDGRLPEVMLPVWFTNNLDVVSSYVQDQSED 110 Query: 517 TLWYKMILPPQ---FDRSKKYPLLIQVYGGPCSQSVRSVFAVNWISYLASKEGMVIALVD 573 L+ + +P + D P+++ ++GG + +++ S LAS +++ V+ Sbjct: 111 CLYLNIYVPTEDDIRDSGGPKPVMVYIHGGSYMEGTGNLYDG---SVLASYGNVIVITVN 167 Query: 574 GR-GTAFQGDKLLYAVYRKLGVYEVEDQITAVRKFIE-MGFI--DEKRIAIWGWSYGGYV 629 R G A G+ D I A+R E +GF D RI ++G GG Sbjct: 168 YRLGVLGFLSTGDQAAKGNYGLL---DLIQALRWTSENIGFFGGDPLRITVFGSGAGGSC 224 Query: 630 SSLALASG---TGLFKCGIA--VAPVSSW 653 +L S GLF+ IA +SSW Sbjct: 225 VNLLTLSHYSEKGLFQRAIAQSGTALSSW 253 >2WQZ-A nrPDB Length = 588 Score = 50.2 bits (118), Expect = 3e-06, Method: Composition-based stats. Identities = 38/157 (24%), Positives = 66/157 (42%), Gaps = 17/157 (10%) Query: 508 IKKLEVDEITLWYKMILPPQ---FDRSKKYPLLIQVYGGPCSQSVRSVFAVNWISYLASK 564 + +E L+ + +P + D++ K P+++ ++GG + ++ S LAS Sbjct: 106 TYVQDQNEDCLYLNIYVPTEDDIHDQNSKKPVMVYIHGGSYMEGTGNMIDG---SILASY 162 Query: 565 EGMVIALVDGR-GTAFQGDKLLYAVYRKLGVYEVEDQITAVRKFIEMGFI---DEKRIAI 620 +++ ++ R G A G+ DQI A+R E D KR+ I Sbjct: 163 GNVIVITINYRLGILGFLSTGDQAAKGNYGLL---DQIQALRWIEENVGAFGGDPKRVTI 219 Query: 621 WGWSYGGYVSSLALASG--TGLFKCGI--AVAPVSSW 653 +G G SL S GLF+ I + +SSW Sbjct: 220 FGSGAGASCVSLLTLSHYSEGLFQKAIIQSGTALSSW 256 >5X6S-A nrPDB Length = 275 Score = 49.4 bits (116), Expect = 5e-06, Method: Composition-based stats. Identities = 28/179 (15%), Positives = 66/179 (36%), Gaps = 7/179 (3%) Query: 536 LLIQVYGGPCSQSVRSVFAVNWISYLASKEGMVIALVDGRGTAFQGDKLLYAVYRKLGVY 595 +++ ++ C+ + + + + L+ + G ++ + D A G Sbjct: 33 IVVAIHY--CTGTGPGYYGDSPYATLSEQYGFIVIYPSSPYSGGCWDVSSQATLTHNGGG 90 Query: 596 EVEDQITAVRKFIEMGFIDEKRIAIWGWSYGGYVSSLALASGTGLFKCGIAVAPVSSWEY 655 V I D ++ + G S G ++++ A+ LF + VS+ + Sbjct: 91 NSNSIANMVTWTISKYGADSSKVFVTGSSSGAMMTNVMAATYPELFAAATVYSGVSAGCF 150 Query: 656 Y-ASVYTERFMGLPTKDD---NLEHYKNSTVMARAEYFRNVDYLLI-HGTADDNVHFQN 709 Y + + + + D EH+ + + Y + + I HG+ D ++ QN Sbjct: 151 YSNTNQVDGWNSTCAQGDVITTPEHWASIAEAMYSGYSGSRPRMQIYHGSIDTTLYPQN 209 >6AVW-A nrPDB Length = 230 Score = 49.4 bits (116), Expect = 6e-06, Method: Composition-based stats. Identities = 27/151 (17%), Positives = 47/151 (31%), Gaps = 28/151 (18%) Query: 613 IDEKRIAIWGWSYGGYVSSLALASGTGLFKCGIAVAPVSSWEYYASVYTERFMGLPTKDD 672 + + + I G S GG ++ ++ G ++ W + S +F Sbjct: 97 TNPENVFICGLSQGGALTLASVLLYPKTLGGGAVLSG---WVPFTSSIISQF-------- 145 Query: 673 NLEHYKNSTVMARAEYFRNVDYLLIHGTADDNVHFQNSAQIAKALVNAQVDFQAMWYSDQ 732 E + L HGT D V F+ L A V + Y Sbjct: 146 -------------PEEAKKTPILWSHGTDDRMVLFEAGQAALPFLKEAGVTCEFKAYPGL 192 Query: 733 NHGLSGLSTNHLYTHMTHFLK----QCFSLS 759 H +S ++ + + LK C L+ Sbjct: 193 GHSISNKELKYIESWIKRRLKGSSSTCLQLN 223 >1MX5-A nrPDB Length = 548 Score = 49.1 bits (115), Expect = 7e-06, Method: Composition-based stats. Identities = 32/154 (20%), Positives = 60/154 (38%), Gaps = 14/154 (9%) Query: 505 KEEIKKLEVDEITLWYKMILPPQFDRSKKYPLLIQVYGGPCSQSVRSVFAVNWISYLASK 564 ++E L++ E L+ + P + + P+++ ++GG S + LA+ Sbjct: 86 RKENIPLKLSEDCLYLNIYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDG---LALAAH 142 Query: 565 EGMVIALVDGR-GTAFQGDKLLYAVYRKLGVYEVEDQITAVRK----FIEMGFIDEKRIA 619 E +V+ + R G G DQ+ A+R G + + Sbjct: 143 ENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHL---DQVAALRWVQDNIASFG-GNPGSVT 198 Query: 620 IWGWSYGGYVSSLALAS--GTGLFKCGIAVAPVS 651 I+G S GG S+ + S LF I+ + V+ Sbjct: 199 IFGESAGGESVSVLVLSPLAKNLFHRAISESGVA 232 >5XB6-A nrPDB Length = 306 Score = 49.1 bits (115), Expect = 8e-06, Method: Composition-based stats. Identities = 23/115 (20%), Positives = 47/115 (40%), Gaps = 10/115 (8%) Query: 522 MILPPQFDRSKKYPLLIQVY-GGPCSQSVRSVFAVNWISYLASKEGMVIALVDGRGTAFQ 580 + PP+FD +++Y ++ + GG + +A +++G V D ++Q Sbjct: 22 IYFPPKFDETRQYQAIVLSHPGGGVKEQTAGTYAKK-----LAEKGFVTIAYD---ASYQ 73 Query: 581 GDKLLYAVYRKLGVYEVEDQITAVRKFIEMGFIDEKRIAIWGWSYG-GYVSSLAL 634 G+ + ED + + ++D RI G G GY ++ A+ Sbjct: 74 GESGGEPRQLENPYIRTEDISAVIDYLTTLSYVDNTRIGAMGICAGAGYTANAAI 128 >5FV4-A nrPDB Length = 544 Score = 48.7 bits (114), Expect = 9e-06, Method: Composition-based stats. Identities = 33/153 (21%), Positives = 58/153 (37%), Gaps = 12/153 (7%) Query: 505 KEEIKKLEVDEITLWYKMILPPQFDRSKKYPLLIQVYGGPCSQSVRSVFAVNWISYLASK 564 ++E E E L+ + P + + P+++ ++GG S + LA+ Sbjct: 87 RKERLIPEFSEDCLYLNIYTPADLTKRGRLPVMVWIHGGGLVVGGASTYDG---LALAAH 143 Query: 565 EGMVIALVDGR-GTAFQGDKLLYAVYRKLGVYEVEDQITAVRKFIE--MGF-IDEKRIAI 620 E +V+ + R G G DQ+ A+ E F D + I Sbjct: 144 ENVVVVAIQYRLGIWGFFSTGDEHSRGNWGHL---DQVAALHWVQENIANFGGDPGSVTI 200 Query: 621 WGWSYGGYVSSLALAS--GTGLFKCGIAVAPVS 651 +G S GG S+ + S LF I+ + V+ Sbjct: 201 FGESAGGESVSVLVLSPLAKNLFHRAISESGVA 233 >3HEA-A nrPDB Length = 271 Score = 47.9 bits (112), Expect = 2e-05, Method: Composition-based stats. Identities = 18/63 (28%), Positives = 28/63 (44%), Gaps = 3/63 (4%) Query: 692 VDYLLIHGTADDNVHFQNSAQIAKALVNAQVDFQAMWYSDQNHGLSGLSTNHLYTHMTHF 751 V L+IHG D V F+ + ++A L+ + Y D HG + L + F Sbjct: 212 VPTLVIHGDGDQIVPFETTGKVAAELIKGA---ELKVYKDAPHGFAVTHAQQLNEDLLAF 268 Query: 752 LKQ 754 LK+ Sbjct: 269 LKR 271 >5HFN-A nrPDB Length = 311 Score = 47.9 bits (112), Expect = 2e-05, Method: Composition-based stats. Identities = 50/238 (21%), Positives = 76/238 (31%), Gaps = 31/238 (13%) Query: 530 RSKKYPLLIQVYGGPCSQSVRSVFAVNWISYLASKEGMVIALVDGRGTAFQG-DKLLYAV 588 +K P ++Q G + F +W G + ++D RGT +G Sbjct: 91 EEEKLPCVVQYIG----YNGGRGFPHDW--LFWPSMGYICFVMDTRGT--RGILDPRTYY 142 Query: 589 YRKLGVYEVEDQITAVRKFIEMGFIDEKRIAIWGWSYGGYVSSL--ALASGTGLFKCGIA 646 YR+ D + AV +D++RI I G S GG ++ AL+ C + Sbjct: 143 YRR----VFTDAVRAVEAAASFPQVDQERIVIAGGSQGGGIALAVSALSKKAKALLCDVP 198 Query: 647 VAPVSSWEYYASVYTERFMGLPTKDDNLEHYKNSTVMARAEYFRNVDY--------LLIH 698 V T + + K V YF V++ L Sbjct: 199 FLCHFR-RAVQLVDTHPYAEITNFLK-THRDKEEIVFRTLSYFDGVNFAARAKIPALFSV 256 Query: 699 GTADDNVHFQNSAQIAKALVNAQVDFQAMWYSDQNHGLSGLSTNHLYTHMTHFLKQCF 756 G D+ S A A + Y NH G S + FLK+ F Sbjct: 257 GLMDNICPP--STVFAAYNYYAG-PKEIRIYPYNNHE-GGGSFQAVEQ--VKFLKKLF 308 >2XLB-A nrPDB Length = 320 Score = 47.5 bits (111), Expect = 2e-05, Method: Composition-based stats. Identities = 54/313 (17%), Positives = 106/313 (33%), Gaps = 56/313 (17%) Query: 480 RTDQEIKILEENKELEN---ALKNIQLPKEEIKKLEVDEITLWYKMILPPQFDRSKKYPL 536 ++ +E++ +E LE+ +K +++ + + +I +Y + D++ +P Sbjct: 30 KSLEELRQVEAEPTLESYDYPVKGVKVYRLTYQSFGHSKIEGFYAVP-----DQTGPHPA 84 Query: 537 LIQVYGGPCSQSVRSVFAVNWISYLASKEGMVIALVDGRGTAF----------QGDKLLY 586 L++ +G S VNW + G + RG + Sbjct: 85 LVRFHGYNASYDDGIHDIVNW-----ALHGYATFGMLVRGQGGSEDTSVTPGGHALGWMT 139 Query: 587 AVYRKLGV----YEVEDQITAVRKFIEMGFIDEKRIAIWGWSYGGYVSSLALASGTGLFK 642 D + A+ +DE RI + G S GG ++A A+ + + K Sbjct: 140 KGILSKDTYYYRGVYLDAVRALEVIQSFPEVDEHRIGVIGGSQGG-ALAIAAAALSDIPK 198 Query: 643 CGIAVAP-VSSWEYYASVYTERFMGLPTKDDNLEHYKNSTV---------------MARA 686 +A P +S++E V E+ P + N +NS + A Sbjct: 199 VVVADYPYLSNFERAVDVALEQ----PYLEINSYFRRNSDPEVEEKAFETLSYFDLINLA 254 Query: 687 EYFRNVDYLLIHGTADDNVHFQNSAQIAKALVNAQVDFQAMWYSDQNHGLSGLSTNHLYT 746 + + + I G D + + A + + D + Y H T Sbjct: 255 GWVKQPTLMAI-GLIDQVTPP---STVFAAYNHLETDKELKVYRYFGHEFIPA----FQT 306 Query: 747 HMTHFLKQCFSLS 759 FL++ LS Sbjct: 307 EKLSFLQKHLLLS 319 >2HDW-A nrPDB Length = 367 Score = 46.7 bits (109), Expect = 4e-05, Method: Composition-based stats. Identities = 28/164 (17%), Positives = 58/164 (35%), Gaps = 8/164 (4%) Query: 472 PISTLHDGRTDQEIKILEENKELENALKNIQLPKEEIKKLEVDEITLWYKMILPPQFDRS 531 P +T +++ + + + ++ ++ ITL + LP Sbjct: 35 PAATTSSNTGGTNMQLQLTQEWDKTFPLSAKVEHRKVTFANRYGITLAADLYLPKN-RGG 93 Query: 532 KKYPLLIQVYGGPCSQSVRSVFAVNWISYLASKEGMVIALVDGRGTAFQGDKLLYAVYRK 591 + P ++ GGP V+ + + +A + G V D T G + Sbjct: 94 DRLPAIVI--GGPFGA-VKEQSSGLYAQTMA-ERGFVTLAFDPSYTGESGGQPRNVASPD 149 Query: 592 LGVYEVEDQITAVRKFIEMGFIDEKRIAIWGWSYGGYVSSLALA 635 + ED AV + ++ +RI + G G ++ A+A Sbjct: 150 INT---EDFSAAVDFISLLPEVNRERIGVIGICGWGGMALNAVA 190 >1A8S-A nrPDB Length = 273 Score = 46.4 bits (108), Expect = 4e-05, Method: Composition-based stats. Identities = 43/269 (15%), Positives = 78/269 (28%), Gaps = 70/269 (26%) Query: 537 LIQVYGGPCSQSVRSVFAVNWISYLASKEGMVIALVDGRGTAFQGDKLLYAVYRKLGVYE 596 ++ +G P + I + +G + D RG + Y Sbjct: 22 IVFSHGWP---LNADSWESQMI--FLAAQGYRVIAHDRRGHGRSSQPWSG---NDMDTY- 72 Query: 597 VEDQITAVRKFIEMGFIDEKRIAIWGWSYGGYVSSLALASGTG--LFKCGIAVA------ 648 +D + D + ++G+S GG + + + K G+ A Sbjct: 73 ADDLAQLIEHL------DLRDAVLFGFSTGGGEVARYIGRHGTARVAKAGLISAVPPLML 126 Query: 649 ---------PVSSWEYYASVY----TERFMGL---PTKDDNLEHYKNSTVMARAEYFRN- 691 P+ ++ ++ + L P N K+S M + + Sbjct: 127 KTEANPGGLPMEVFDGIRQASLADRSQLYKDLASGPFFGFNQPGAKSSAGMVDWFWLQGM 186 Query: 692 ---------------------------VDYLLIHGTADDNVHFQNSAQIAKALVNAQVDF 724 V L++HG AD V + S + ALV Sbjct: 187 AAGHKNAYDCIKAFSETDFTEDLKKIDVPTLVVHGDADQVVPIEASGIASAALVKGST-- 244 Query: 725 QAMWYSDQNHGLSGLSTNHLYTHMTHFLK 753 YS HGL+ + L + F+K Sbjct: 245 -LKIYSGAPHGLTDTHKDQLNADLLAFIK 272 >3HXK-A nrPDB Length = 276 Score = 46.4 bits (108), Expect = 5e-05, Method: Composition-based stats. Identities = 40/214 (18%), Positives = 86/214 (40%), Gaps = 24/214 (11%) Query: 534 YPLLIQVYGGPCSQSVRSVFAVNWISYLASKEGMVIALVDG----RGTAFQGDKLLYAVY 589 +P +I GG + +++LA +G + L++ +GT + + Sbjct: 43 FPAIIICPGGGYQHISQRESDPLALAFLA--QGYQVLLLNYTVMNKGTNYN--------F 92 Query: 590 RKLGVYEVEDQITAVRKFIEMGFIDEKRIAIWGWSYGGYVSSLALASGT-GLFKCGIAVA 648 + EV+ + + + + I+ +++ + G S GG++++ S K I Sbjct: 93 LSQNLEEVQAVFSLIHQNHKEWQINPEQVFLLGCSAGGHLAAWYGNSEQIHRPKGVILCY 152 Query: 649 PVSSWEY-YASVYTERFMGLPTKDDNLEHYKNSTVMARAEYFRNVDYLLIHGTADDNVHF 707 PV+S+ + + S + + +N+ Y S + + + H D+ V Sbjct: 153 PVTSFTFGWPSDLSHFNFEI----ENISEYNISEKVTSS----TPPTFIWHTADDEGVPI 204 Query: 708 QNSAQIAKALVNAQVDFQAMWYSDQNHGLSGLST 741 NS + L QV F+A ++ HG+S + Sbjct: 205 YNSLKYCDRLSKHQVPFEAHFFESGPHGVSLANR 238 >2OCI-A nrPDB Length = 254 Score = 46.4 bits (108), Expect = 5e-05, Method: Composition-based stats. Identities = 35/221 (15%), Positives = 65/221 (29%), Gaps = 52/221 (23%) Query: 567 MVIALVDGRGTAFQ---GDKLLYAVYRKLGVYEVEDQITAVRKFIEMGFIDEKRIAIWGW 623 + D RG + + D AV + F K++++ GW Sbjct: 52 FTVVAWDPRGYGHSRPPDRDFPADFFER-------DAKDAVDLMKALKF---KKVSLLGW 101 Query: 624 SYGGYVSSLALASGTG-LFKCGIAVA----------------PVSSW-----EYYASVYT 661 S GG + +A A + K I A VS W + ++Y Sbjct: 102 SDGGITALIAAAKYPSYIHKMVIWGANAYVTDEDSMIYEGIRDVSKWSERTRKPLEALYG 161 Query: 662 ERFM---------GLPTKDDNLEHYKNSTVMARAEYFRNVDYLLIHGTADDNVHFQNSAQ 712 + G+ + ++ R + L++HG D V ++ Sbjct: 162 YDYFARTCEKWVDGIRQFKHLPDGNICRHLLPRVQ----CPALIVHGEKDPLVPRFHADF 217 Query: 713 IAKALVNAQVDFQAMWYSDQNHGLSGLSTNHLYTHMTHFLK 753 I K + ++ + H L + FL+ Sbjct: 218 IHKHVKGSR----LHLMPEGKHNLHLRFADEFNKLAEDFLQ 254 >3LS2-A nrPDB Length = 280 Score = 46.0 bits (107), Expect = 7e-05, Method: Composition-based stats. Identities = 53/260 (20%), Positives = 89/260 (34%), Gaps = 36/260 (13%) Query: 517 TLWYKMILPPQFDRSKKYPLLIQVYGGPCSQSVRSVFAVNWISYLASKEGMVIALVD--G 574 T+ + + LPP S K P+L + G C+ A + A++ G+ I D Sbjct: 28 TMRFAVFLPPGASESNKVPVLYWLSGLTCTDENFMQKAGAFKK--AAELGIAIVAPDTSP 85 Query: 575 RGTA---------FQGDKL-LYAVYRKLGV--YEVEDQITAVRKFIEMGFIDEKRIAIWG 622 RG QG + A + + + IE F AI G Sbjct: 86 RGDNVPNEDSYDFAQGAGFYVNATQAPYNTHFNMYDYVVNELPALIEQHFPVTSTKAISG 145 Query: 623 WSYGGYVSSLALASGTGLFKCGIAVAPVSS-----WEYYA-SVYTERFMGLPTKDDNLEH 676 S GG+ + + + A +P+ + W A + Y L Sbjct: 146 HSMGGHGALMIALKNPQDYVSASAFSPIVNPINCPWGVKAFTGY------LGADKTTWAQ 199 Query: 677 YKNSTVMARAEYFRNVDYLLIHGTADDNVHFQNSAQIAKALVNAQVDFQAMWYSDQNHGL 736 Y + +MA+AE + L+ G AD+ + Q Q A+ Q D+ + Sbjct: 200 YDSCKLMAKAEQSNYLPMLVSQGDADNFLDEQLKPQNLVAVAK-QKDYPLTLEMQTGY-- 256 Query: 737 SGLSTNHLYTHMTHFLKQCF 756 +H Y ++ F+ Q Sbjct: 257 -----DHSYFFISSFIDQHL 271 >4WY5-A nrPDB Length = 332 Score = 45.2 bits (105), Expect = 9e-05, Method: Composition-based stats. Identities = 57/286 (19%), Positives = 103/286 (36%), Gaps = 53/286 (18%) Query: 484 EIKILEENKELENALKNIQLPK--EEIKKLEVDEITLWYKMILPPQFDRSKKYPLLIQVY 541 ++K++ E+ E NI+LP+ EE K +E D TL ++ PP + + P+LI ++ Sbjct: 29 DLKVVRESSEARQLAANIKLPEVIEEDKVVESDGKTLKLTIVRPPGTED-QILPVLIFLH 87 Query: 542 GGPCSQSVRSVFAVNWISYLASKEGMVIALVDGRGTAFQGDKLLYAVYRKLGVYEVEDQI 601 GG + + L K +V VD + K A+ E+ Sbjct: 88 GGGFV-FGSKYTHIKPVRDLTVKANVVTVFVDYSLSPE--AKFPTAI---------EEIY 135 Query: 602 TAVRKFIEMGF---IDEKRIAIWGWSYGGYV--------------------------SSL 632 A+ E I+ + +A+ G S G + +++ Sbjct: 136 AAILWVRENASSLNINAEALAVAGDSAGATLSAAVSIYAKEKGLSAAIKTQVLIYPATAV 195 Query: 633 ALASGT--GLFKCGIAVAPVSSWEYYASVYTERFMGLPTKDDNLEHYKNSTVMARAEYFR 690 + A LF G + +++++ Y LP L + +A Sbjct: 196 SHAKYESYKLFGNGDYILSAEDLKFFSNAY------LPAPASELNDKLATLELATKADLE 249 Query: 691 NVDYLLIHGTADDNVHFQNSAQIAKALVNAQVDFQAMWYSDQNHGL 736 + L+ TA+ +V + A+ L A VD A+ HG Sbjct: 250 GLPPALLF-TAESDVLRDEGEKYAQQLAEAGVDVAAVRVLGAVHGF 294 >6GUD-A nrPDB Length = 292 Score = 45.2 bits (105), Expect = 1e-04, Method: Composition-based stats. Identities = 40/184 (21%), Positives = 65/184 (35%), Gaps = 33/184 (17%) Query: 496 NALKNIQLPKEEIKKLEVDEITLWY-KMILPPQFDRSKK----YPLLIQVYGGPCSQSVR 550 + + LP E LE D + ++ P ++ + P++ V G + Sbjct: 3 DRPTPVPLPNSEQFYLENDRGEPYLIQVSWPLHWEDKQTGRGPLPIIYIVDGNALFLTAT 62 Query: 551 -SVFAVNWISYLASKEGMVIALVDGRGTAFQGDKLLYAVYRKL--------------GVY 595 + + S+ A G +I + G +G KL A R G Sbjct: 63 EAAWRRAAASHFAG--GGIIVAI---GYPLKG-KLYDARRRSFDLTPPTACAPVGYGGAD 116 Query: 596 EVEDQIT-----AVRKFIEMGFIDEKRIAIWGWSYGGYVSSLALASGTGLFKCGIAVAPV 650 D I AV+ + R A++G SYGG ++ AL + F C IA +P Sbjct: 117 VFLDFIENSVRPAVQ--ARFPQVSLAREALYGHSYGGLLALHALFTRPQSFDCYIASSPS 174 Query: 651 SSWE 654 W Sbjct: 175 IWWN 178 >1THG-A nrPDB Length = 544 Score = 44.4 bits (103), Expect = 2e-04, Method: Composition-based stats. Identities = 26/138 (18%), Positives = 50/138 (36%), Gaps = 11/138 (7%) Query: 510 KLEVDEITLWYKMILPPQFDRSKKYPLLIQVYGGPCSQSVRSVFAVNWISYLASKEG--M 567 + ++E L+ + P K P+++ +YGG + + N + G + Sbjct: 98 TVSMNEDCLYLNVFRPAGTKPDAKLPVMVWIYGGAFVYGSSAAYPGNSYVKESINMGQPV 157 Query: 568 VIALVDGRGTAF---QGDKLLYAVYRKLGVYEVEDQITAVRKFIE--MGF-IDEKRIAIW 621 V ++ R F GD + G + DQ + + F D ++ I+ Sbjct: 158 VFVSINYRTGPFGFLGGDAITAEGNTNAG---LHDQRKGLEWVSDNIANFGGDPDKVMIF 214 Query: 622 GWSYGGYVSSLALASGTG 639 G S G + L + G Sbjct: 215 GESAGAMSVAHQLIAYGG 232 >2YH2-A nrPDB Length = 313 Score = 43.3 bits (100), Expect = 4e-04, Method: Composition-based stats. Identities = 48/292 (16%), Positives = 98/292 (33%), Gaps = 51/292 (17%) Query: 469 PGIPISTLHDGRTDQEIKILEENKELENALKNIQLPKEEIKKLEVDEITLWYKMILPPQF 528 P + + T+ + + +++ E + +++I +P + ++ P Sbjct: 22 PDMDVKTVREQFEKSSLILVKMANEPIHRVEDITIPGR--------GGPIRARVYRPRD- 72 Query: 529 DRSKKYPLLIQVYGGPCSQSVRSVFAVNWISYLASKEGMVIALVDGRGTAFQGDKLLYAV 588 ++ P ++ +GG + LA+ G V+ VD R K AV Sbjct: 73 --GERLPAVVYYHGGGFVLGSVET-HDHVCRRLANLSGAVVVSVDYRLAPEH--KFPAAV 127 Query: 589 YRKLGVYEVEDQITAVRKFI----EMGFIDEKRIAIWGWSYGGYVSS----LALASGTGL 640 ED A + ++G +D +IA+ G S GG +++ +A G Sbjct: 128 ---------EDAYDAAKWVADNYDKLG-VDNGKIAVAGDSAGGNLAAVTAIMARDRGESF 177 Query: 641 FKCGIAVAPVSSWEYYASVYTERFMG---------LPTKDDNLEHYKNSTVMAR------ 685 K + + P + +V + G L K ++ Sbjct: 178 VKYQVLIYPAVNLTGSPTVSRVEYSGPEYVILTADLMAWFGRQYFSKPQDALSPYASPIF 237 Query: 686 AEYFRNVDYLLIHGTADDNVHFQNSAQIAKALVN-AQVDFQAMWYSDQNHGL 736 A+ L+I D ++ ++ L+ V A+ Y+ HG Sbjct: 238 ADLSNLPPALVITAEYDP---LRDEGELYAHLLKTRGVRAVAVRYNGVIHGF 286 >4B6G-A nrPDB Length = 283 Score = 43.3 bits (100), Expect = 4e-04, Method: Composition-based stats. Identities = 20/161 (12%), Positives = 56/161 (34%), Gaps = 16/161 (9%) Query: 600 QITAVRKFIEMGFIDEKRIAIWGWSYGGYVSSLALASGTGLFKCGIAVAPVS--SWEYYA 657 + + + IE F + +I G S GG+ + + ++ A +P+ S + Sbjct: 129 ILNELPRLIEKHFPTNGKRSIMGHSMGGHGALVLALRNQERYQSVSAFSPILSPSLVPWG 188 Query: 658 SVYTERFMGLPTKDDNLEHYKNSTVMARAEYFRNVDYLLIHGTADDNVHFQ-NSAQIAKA 716 ++G + + Y ++++ + + + + G D+ + Q + + Sbjct: 189 EKAFTAYLG--KDREKWQQYDANSLIQQGYKVQGMR--IDQGLEDEFLPTQLRTEDFIET 244 Query: 717 LVNAQVDFQAMWYSDQNHGLSGLSTNHLYTHMTHFLKQCFS 757 A ++ +H Y + F+ + + Sbjct: 245 CRAANQPVDVRFHKGYDHS---------YYFIASFIGEHIA 276 >4WY8-A nrPDB Length = 327 Score = 42.5 bits (98), Expect = 6e-04, Method: Composition-based stats. Identities = 49/302 (16%), Positives = 103/302 (34%), Gaps = 49/302 (16%) Query: 487 ILEENKELENALKNIQLPKEEIKKLEVDEITLWYKMILPPQFDRSKKYPLLIQVYGGPCS 546 I+++ K LE EE + + + P ++ P ++ +GG Sbjct: 38 IIDDPKALEGLPDVY---LEEKTINRKNGSKIELTITRPLD-TENQVLPPIVFFHGG-GW 92 Query: 547 QSVRSVFAVNWISYLASKEGMVIALVDGRGTAFQGDKLLYAVYRKLGVYEVEDQITAVRK 606 + + L + + V+ + + A+ E+ + AV Sbjct: 93 VVGSKLTHRRTVYELTVRARAAVIFVNYSLSPE--VRFPTAL---------EECLDAVVW 141 Query: 607 FIEMGF-----IDEKRIAIWGWSYGGYVSSLALAS----GTGLFKCGIAVAPVSSWEYYA 657 + +D ++ + G S GG +S++ G + K + + PV+ + Sbjct: 142 VAKEENAKSINVDPTKLVVAGDSAGGNLSAVVCIRAKQLGLNIIKGQVLIYPVTDDNFET 201 Query: 658 SVY---TERFM------------GLPTKDDNLEHYKNSTVMARAEYFRNVD-YLLIHGTA 701 Y E + +P K D + + A + R + L+I A Sbjct: 202 DSYKQFAENYYLTRKLMVWFFDHYIPDKKDRQSIF-ACPLKASIDDLRVLPRALVITAEA 260 Query: 702 DDNVHFQNSAQIAKALVNAQVDFQAMWYSDQNHGLS-----GLSTNHLYTHMTHFLKQCF 756 D V + A+ L+ A D A+ Y HG+ + + + H+ +L++ + Sbjct: 261 D--VLREEGEAYARKLIEAGNDVTAVRYLGIIHGIFNLATLSPTGSEILDHIVAWLQKTW 318 Query: 757 SL 758 L Sbjct: 319 KL 320 >3DYV-A nrPDB Length = 251 Score = 42.5 bits (98), Expect = 6e-04, Method: Composition-based stats. Identities = 46/258 (17%), Positives = 88/258 (34%), Gaps = 53/258 (20%) Query: 525 PPQFDRSKKYPLLIQVY-GGPCSQSVRSVFAVNWISYLASKEGMVIALVDGRGTAFQGDK 583 P +++ + +L+ Y G P N+++ + G + + G Sbjct: 15 PFEYEGTDTGVVLLHAYTGSPNDM--------NFMARALQRSGYGVYVPLFSGH------ 60 Query: 584 LLYAVYRKLGVYEVEDQITAVR---KFIEMG------FIDEKRIAIWGWSYGGYVSSLAL 634 G E D +T + E ++ ++G S GG + AL Sbjct: 61 ---------GTVEPLDILTKGNPDIWWAESSAAVAHMTAKYAKVFVFGLSLGGIFAMKAL 111 Query: 635 ASGTGLFKCGIAVAPVS--------SWEYYASVYTERFMGLPTKDDNLEHY--------- 677 + G+ G+ +P+ + YA Y R G + + Y Sbjct: 112 ETLPGITAGGVFSSPILPGKHHLVPGFLKYAE-YMNRLAGKSDESTQILAYLPGQLAAID 170 Query: 678 KNSTVMARAEYFRNVDYLLIHGTADDNVHFQNSAQIAKALVNAQVDFQAMWYSDQNHGLS 737 + +T +A + D+ V + + Q+ AL+NA WY D H ++ Sbjct: 171 QFATTVAADLNLVKQPTFIGQAGQDELVDGRLAYQLRDALINAAR-VDFHWYDDAKHVIT 229 Query: 738 GLSTNH-LYTHMTHFLKQ 754 S +H L + F++Q Sbjct: 230 VNSAHHALEEDVIAFMQQ 247 >1UFO-A nrPDB Length = 238 Score = 42.5 bits (98), Expect = 7e-04, Method: Composition-based stats. Identities = 30/142 (21%), Positives = 52/142 (36%), Gaps = 18/142 (12%) Query: 618 IAIWGWSYGGYVSSLALASGTGLFKCGIAVAPVSSWEYYASVYTERFMGLP----TKDDN 673 + + G S G +V+ L LA G F+ P + S + M LP +D Sbjct: 107 LFLAGGSLGAFVAHLLLAEG---FR------PRGVLAFIGSGFP---MKLPQGQVVEDPG 154 Query: 674 LEHYKNSTVMARAEYFRNVDYLLIHGTADDNVHFQNSAQIAKALVNAQVDFQAMWY--SD 731 + + R E + V L +HG+ D V + +AL + + + Sbjct: 155 VLALYQAPPATRGEAYGGVPLLHLHGSRDHIVPLARMEKTLEALRPHYPEGRLARFVEEG 214 Query: 732 QNHGLSGLSTNHLYTHMTHFLK 753 H L+ L + H+L+ Sbjct: 215 AGHTLTPLMARVGLAFLEHWLE 236 >5FDF-A nrPDB Length = 337 Score = 42.5 bits (98), Expect = 7e-04, Method: Composition-based stats. Identities = 50/261 (19%), Positives = 75/261 (28%), Gaps = 51/261 (19%) Query: 530 RSKKYPLLIQVYGGPCSQSVRSVFAVNWISYLASKEGMVIALVDGRGTAFQGDKLLYAVY 589 +K P ++Q G + F +W G + ++D RG QG L Sbjct: 91 EEEKLPCVVQYIG----YNGGRGFPHDW--LFWPSMGYICFVMDTRG---QGSGWLKGDT 141 Query: 590 RKLGVYEVE------------------------DQITAVRKFIEMGFIDEKRIAIWGWSY 625 V+ D + AV +D++RI I G S Sbjct: 142 PDYPEGPVDPQYPGFMTRGILDPRTYYYRRVFTDAVRAVEAAASFPQVDQERIVIAGGSQ 201 Query: 626 GGYVSSL--ALASGTGLFKCGIAVAPVSSWEYYASVYTERFMGLPTKDDNLEHYKNSTVM 683 GG ++ AL+ C + V T + + K V Sbjct: 202 GGGIALAVSALSKKAKALLCDVPFLCHFR-RAVQLVDTHPYAEITNFLK-THRDKEEIVF 259 Query: 684 ARAEYFRNVDY--------LLIHGTADDNVHFQNSAQIAKALVNAQVDFQAMWYSDQNHG 735 YF V++ L G D+ S A A + Y NH Sbjct: 260 RTLSYFDGVNFAARAKIPALFSVGLMDNICPP--STVFAAYNYYAG-PKEIRIYPYNNHE 316 Query: 736 LSGLSTNHLYTHMTHFLKQCF 756 G S + FLK+ F Sbjct: 317 -GGGSFQAVEQ--VKFLKKLF 334 >3RAR-A nrPDB Length = 534 Score = 42.5 bits (98), Expect = 8e-04, Method: Composition-based stats. Identities = 34/176 (19%), Positives = 64/176 (36%), Gaps = 22/176 (12%) Query: 487 ILEENKELENALKNIQLPKEEIKKLEVDEITLWYKMILPPQFDRSKKYPLLIQVYGGPCS 546 EEN + AL + K E L ++ PP P+++ ++GG Sbjct: 68 TYEENL-PKAALDLVMQSKVFEAVSPSSEDCLTINVVRPPGTKAGANLPVMLWIFGGGFE 126 Query: 547 QSVRSVFAVNWISYLASKEG--MVIALVDGRGTAF---QGDKLLYAVYRKLGVYEVEDQI 601 S F + + G ++ V+ R +++ GD++ G ++DQ Sbjct: 127 VGGTSTFPPAQMITKSIAMGKPIIHVSVNYRVSSWGFLAGDEIKAEGSANAG---LKDQR 183 Query: 602 TAVRKFIEMGFI---DEKRIAIWGWSYGGYVSSLALA---------SGTGLFKCGI 645 ++ + D ++ I+G S G +S + G LF+ GI Sbjct: 184 LGMQWVADNIAAFGGDPTKVTIFGESAGS-MSVMCHILWNDGDNTYKGKPLFRAGI 238 >1C5K-A nrPDB Length = 439 Score = 42.1 bits (97), Expect = 8e-04, Method: Composition-based stats. Identities = 55/327 (16%), Positives = 91/327 (27%), Gaps = 79/327 (24%) Query: 123 RYSYTATYYIYDLSNGEFVRGNELPRPIQYLCWSPVGSKLAYVYQNNIYLKQRPGDPPFQ 182 ++ Y YD N V + P+P+ WSP GSKLAYV G Sbjct: 178 QFPYELRVSDYDGYNQFVV--HRSPQPLMSPAWSPDGSKLAYV-------TFESGRSALV 228 Query: 183 ITFNGRENKIFNGIPDWVYEEEMLATKYALWWSPNGKFLAYAEFNDTDIPVIAYSYYGDE 242 I + NG V A +SP+G LA+A Sbjct: 229 I------QTLANGAVRQVAS--FPRHNGAPAFSPDGSKLAFALS---------------- 264 Query: 243 QYPRTINIPYPKAGAKNPVVRIFIIDTTYPAYVGPQEVPVPAMIASSDYYFSWLTWVTDE 302 K G+ N ++++D + ++ S++ + TW D Sbjct: 265 -----------KTGSLN----LYVMD------LASGQIRQVTDGRSNN---TEPTWFPDS 300 Query: 303 RVCLQWLKRVQNVSVLSICDFREDWQTWDCPKTQEHIEESRTGWAGGFFVSTPVFSYDAI 362 QN++ + + R W G V S Sbjct: 301 ----------QNLA----FTSDQAGRPQVYKVNINGGAPQRITWEGSQNQDADVSS--DG 344 Query: 363 SYYKIFSDKDGYKHIHYIKDTVENAIQITSGKWEAINIFRVTQDSLFYSSNEFEEYPG-- 420 + + S G +HI ++S + + YSS++ Sbjct: 345 KFMVMVSSNGGQQHIAKQDLATGGVQVLSSTFLDETPSLAPNGTMVIYSSSQGMGSVLNL 404 Query: 421 ----RRNIYRISIGSYPPSKKCVTCHL 443 R R+ + +L Sbjct: 405 VSTDGRFKARLPATDGQVKFPAWSPYL 431 >4R40-A nrPDB Length = 411 Score = 42.1 bits (97), Expect = 0.001, Method: Composition-based stats. Identities = 53/327 (16%), Positives = 91/327 (27%), Gaps = 79/327 (24%) Query: 123 RYSYTATYYIYDLSNGEFVRGNELPRPIQYLCWSPVGSKLAYVYQNNIYLKQRPGDPPFQ 182 ++ + YD N V + P P+ WSP GSK+AYV G Sbjct: 158 KFPHELRVSDYDGYNQFVV--HRSPEPLMSPAWSPDGSKIAYV-------TFESGKSALV 208 Query: 183 ITFNGRENKIFNGIPDWVYEEEMLATKYALWWSPNGKFLAYAEFNDTDIPVIAYSYYGDE 242 I + NG V A +SP+G LA+A Sbjct: 209 I------QTLANGAIRQVAS--FPRHNGAPAFSPDGTKLAFALS---------------- 244 Query: 243 QYPRTINIPYPKAGAKNPVVRIFIIDTTYPAYVGPQEVPVPAMIASSDYYFSWLTWVTDE 302 K+G+ N ++++D + ++ S++ + +W D Sbjct: 245 -----------KSGSLN----LYVMD------LASGQISQVTDGRSNN---TEPSWFPDS 280 Query: 303 RVCLQWLKRVQNVSVLSICDFREDWQTWDCPKTQEHIEESRTGWAGGFFVSTPVFSYDAI 362 QN++ + + R W G + V S D Sbjct: 281 ----------QNLA----YTSDQGGRPQVYKVNINGGVPQRITWEGSQNQNADV-SPDG- 324 Query: 363 SYYKIFSDKDGYKHIHYIKDTVENAIQITSGKWEAINIFRVTQDSLFYSSNEFEEYPG-- 420 + + S G +HI +T + + YSS + Sbjct: 325 KFLVLVSSNGGAQHIAKQDLETGAVQVLTDTLLDETPSIAPNGTMVIYSSTQGLGSVLQL 384 Query: 421 ----RRNIYRISIGSYPPSKKCVTCHL 443 R R+ + +L Sbjct: 385 VSTDGRFKARLPATDGQVKFPAWSPYL 411 >2YYS-A nrPDB Length = 286 Score = 41.7 bits (96), Expect = 0.001, Method: Composition-based stats. Identities = 39/176 (22%), Positives = 66/176 (37%), Gaps = 25/176 (14%) Query: 505 KEEIKKLEVDEITLWYKMILPPQFDRSKKYPLLIQVYGGPCSQSVRSVFAVNWISYLASK 564 +EEI + V E L+ + + P + P L ++GGP + V YL Sbjct: 2 REEIGYVPVGEAELYVEDVGPVEG------PALFVLHGGPGGNAY--VLREGLQDYL--- 50 Query: 565 EGMVIALVDGRGTAFQGDKLLYAVYRKLGVYE--VEDQITAVRKFIEMGFIDEKRIAIWG 622 EG + D RG+ G L +L + VED + +R + Sbjct: 51 EGFRVVYFDQRGS---GRSLELPQDPRLFTVDALVEDTLLLAEALG------VERFGLLA 101 Query: 623 WSYGGYVSSLALASGTGLFKCGIAVAPVSSWEYYASVYTER--FMGLPTKDDNLEH 676 +G V+ L + I +AP ++ + A+ E LP ++NL+ Sbjct: 102 HGFGAVVALEVLRRFPQA-EGAILLAPWVNFPWLAARLAEAAGLAPLPDPEENLKE 156 >2O7R-A nrPDB Length = 338 Score = 41.7 bits (96), Expect = 0.001, Method: Composition-based stats. Identities = 31/136 (22%), Positives = 49/136 (36%), Gaps = 24/136 (17%) Query: 520 YKMILPPQ-FDRSKKYPLLIQVYGGPCSQ-SVRSVFAVNWISYLASKEGMVIALVDGRGT 577 ++ LP S K PL++ +GG S S ++ +A G+VIA VD R Sbjct: 68 VRLFLPRHALYNSAKLPLVVYFHGGGFILFSAASTIFHDFCCEMAVHAGVVIASVDYR-- 125 Query: 578 AFQGDKLLYAVYRKLGVYEVEDQITAVRKFIEM------GFIDEKRIAIWGWSYGGYVSS 631 + + +D + A++ + F D I G S GG Sbjct: 126 ----LAPEHRL-----PAAYDDAMEALQWIKDSRDEWLTNFADFSNCFIMGESAGG---- 172 Query: 632 LALASGTGLFKCGIAV 647 +A GL +A Sbjct: 173 -NIAYHAGLRAAAVAD 187 >2C7B-A nrPDB Length = 311 Score = 41.7 bits (96), Expect = 0.001, Method: Composition-based stats. Identities = 44/268 (16%), Positives = 88/268 (32%), Gaps = 53/268 (19%) Query: 499 KNIQLPKEEIKKLEV--DEITLWYKMILPPQFDRSKKYPLLIQVYGGPCSQSVRSVFAVN 556 +Q P E + + + ++ ++ P ++ P ++ +GG + Sbjct: 39 AAVQEPIAETRDVHIPVSGGSIRARVYFP---KKAAGLPAVLYYHGGGFVFGSIET-HDH 94 Query: 557 WISYLASKEGMVIALVDGRGTAFQGDKLLYAVYRKLGVYEVEDQITAVRKFI----EMGF 612 L+ V+ VD R K AV ED A++ E+G Sbjct: 95 ICRRLSRLSDSVVVSVDYRLAPEY--KFPTAV---------EDAYAALKWVADRADELG- 142 Query: 613 IDEKRIAIWGWSYGGYVSSLA----LASGTGLFKCGIAVAPVSSWEYYASV--------- 659 +D RIA+ G S GG ++++ SG L K + + PV + + Sbjct: 143 VDPDRIAVAGDSAGGNLAAVVSILDRNSGEKLVKKQVLIYPVVNMTGVPTASLVEFGVAE 202 Query: 660 -----------YTERFMGLPTKDDNLEHYKNSTVMARAEYFRNVDYLLIHGTADDNVHFQ 708 + +++ P + +K S ++A L++ D Sbjct: 203 TTSLPIELMVWFGRQYLKRP---EEAYDFKASPLLADLGGLP--PALVVTAEYDP--LRD 255 Query: 709 NSAQIAKALVNAQVDFQAMWYSDQNHGL 736 A + + A+ ++ HG Sbjct: 256 EGELYAYKMKASGSRAVAVRFAGMVHGF 283 >1ODT-C nrPDB Length = 318 Score = 41.3 bits (95), Expect = 0.002, Method: Composition-based stats. Identities = 49/293 (16%), Positives = 92/293 (31%), Gaps = 51/293 (17%) Query: 494 LENALKNIQLPKEEIKKLEVDEITLWYKMILPPQFDRSKKYPLLIQVYGGPCSQSVRSVF 553 ++ +++ + K IT WY + D+ +P +++ +G S Sbjct: 47 VDYPADGVKVYRLTYKSFGNARITGWYAVP-----DKEGPHPAIVKYHGYNASYDGEIHE 101 Query: 554 AVNWISYLASKEGMVIALVDGRGTA----------FQGDKLLYAVYRKLGV----YEVED 599 VNW + G + RG + D Sbjct: 102 MVNW-----ALHGYATFGMLVRGQQSSEDTSISPHGHALGWMTKGILDKDTYYYRGVYLD 156 Query: 600 QITAVRKFIEMGFIDEKRIAIWGWSYGGYVSSLALASGTGLFKCGIAVAPVSSWEYYASV 659 + A+ +DE RI + G + GG ++ A A+ + + K +A P Y S Sbjct: 157 AVRALEVISSFDEVDETRIGVTGGAQGGGLTIAA-AALSDIPKAAVADYP------YLSN 209 Query: 660 YTERFMGL----PTKDDNLEHYKNSTVMARAEYFRNVDYLLIHGTADDNVHFQNSAQIAK 715 + ER + + P + N +N + + + + Y I AD ++ Sbjct: 210 F-ERAIDVALEEPYLEINSFFRRNGSPETEVQAMKTLSYFDIMNLADRVKVP---VLMSI 265 Query: 716 ALVNAQVDFQAMWYSDQNHGLSGLSTN------HLY-----THMTHFLKQCFS 757 L++ ++ NH + H Y T F KQ Sbjct: 266 GLIDKVTPPST-VFAAYNHLETKKELKVYRYFGHEYIPAFQTEKLAFFKQHLK 317 >6GI5-A nrPDB Length = 282 Score = 41.3 bits (95), Expect = 0.002, Method: Composition-based stats. Identities = 49/279 (17%), Positives = 84/279 (30%), Gaps = 57/279 (20%) Query: 490 ENKELENALKNIQLP-KEEIKKLEVDEITLWYKMIL--PPQFDRSKKYPLLIQVYGGPCS 546 E + L+ LP + L+ + Y++ L P Q + YP++ + G Sbjct: 8 EATMDRSLLQRQDLPYRFSAVDLDSVDGQRHYRLWLGRPLQAPPAAGYPVVWMLDGNAAV 67 Query: 547 QSVRSVFAVNWISYLASKEGMVIALVDGRGTAFQ----GDKLLYAVYRKLGVYEVEDQIT 602 + + LA + ++ + R T + G Y G + D + Sbjct: 68 ----GALDESTLRRLADGDAPLLVAIGYR-TPLRIDRAGRTFDY-TPASPGQADQRDPLN 121 Query: 603 AVR-----------------KFIEMGFIDEKRIAIWGWSYGGYVSSLALASGTGLFKCGI 645 + +D R +WG SYGG + AL + G F Sbjct: 122 GLPSGGADAFLDLLRDGMRPAVAAQAPLDTARQTLWGHSYGGLLVLHALFTRPGEFARYA 181 Query: 646 AVAPVSSWEYYASVYTERFMGLPTKDDNLEHYKNSTVMARAEYFRNVDYLLIHGTADDNV 705 A +P S W ++ ER + L + + LL G+A+ Sbjct: 182 AASP-SLWWRDGAILGER----AGLEQRLRGKRA-------------ELLLWRGSAEPAS 223 Query: 706 H----FQNSAQIAKALVN-----AQVDFQAMWYSDQNHG 735 Q LV+ A + HG Sbjct: 224 PRGSLKAEPGQAMARLVDDLRRVAGLTLDFQPLDGLGHG 262 >4DGQ-A nrPDB Length = 280 Score = 41.0 bits (94), Expect = 0.002, Method: Composition-based stats. Identities = 14/62 (22%), Positives = 26/62 (41%), Gaps = 3/62 (4%) Query: 692 VDYLLIHGTADDNVHFQNSAQIAKALVNAQVDFQAMWYSDQNHGLSGLSTNHLYTHMTHF 751 + L+IHG D V + +S ++ LV + Y HG+ + + + F Sbjct: 221 IPVLVIHGDDDQVVPYADSGVLSAKLVKNGK---LITYKGAPHGIPTTHADKVNADLLEF 277 Query: 752 LK 753 L+ Sbjct: 278 LQ 279 >4BZW-A nrPDB Length = 282 Score = 41.0 bits (94), Expect = 0.002, Method: Composition-based stats. Identities = 39/243 (16%), Positives = 73/243 (30%), Gaps = 41/243 (16%) Query: 520 YKMILPPQFDRSKKYPLLIQVYGGPCSQSVRSVFAVNWISYLASKEGMVIALVDGRGTAF 579 Y + F+ + YP++I GG + A +A+ GM +++ Sbjct: 20 YWLDQISDFETAVDYPIMIICPGGGFTYHSGREEAPIATRMMAA--GMHTVVLNY----- 72 Query: 580 QGDKLLYAVYRKLGVYEVEDQITAV--RKFIEMG---FIDEKRIAIWGWSYGGYV----- 629 + VY Q +D +RI + G+S GG+V Sbjct: 73 ------QLIVGDQSVYPWALQQLGATIDWITTQASAHHVDCQRIILAGFSAGGHVVATYN 126 Query: 630 ---------SSLALASGTGLFKCGIAVAPVSSWE-YYASVYTERFMGLPTKDDNLEHYKN 679 + L G I PV + + R + + Sbjct: 127 GVATQPELRTRYHLDHYQGQHAAIILGYPVIDLTAGFPTTSAAR----NQITTDARLWAA 182 Query: 680 STVMARAEYFRNVDYLLIHGTADDNVHFQNSAQIAKALVNAQVDFQAMWYSDQNHGLSGL 739 ++ A + D++V NS + +A++ QV + HGL+ Sbjct: 183 QRLVTPASK----PAFVWQTATDESVPPINSLKYVQAMLQHQVATAYHLFGSGIHGLALA 238 Query: 740 STN 742 + Sbjct: 239 NHV 241 >5LZ5-A nrPDB Length = 388 Score = 40.6 bits (93), Expect = 0.002, Method: Composition-based stats. Identities = 41/203 (20%), Positives = 73/203 (35%), Gaps = 63/203 (31%) Query: 518 LWYKMILPPQ----FDRSKKYPLLIQVYGGPCSQSVRSVFAVNWISYLASKEGMVIALVD 573 L+ M P +KYPL++ +G +++ S ++ + G ++A V+ Sbjct: 79 LFGSMTTPANWNSPLRPGEKYPLVVFSHGLGAFRTLYSAIGID-----LASHGFIVAAVE 133 Query: 574 GR---GTAFQ----------GDK-LLYAVYRKLGVYE------------VEDQITAVRKF 607 R +A GDK LY R L E ++ A+ Sbjct: 134 HRDRSASATYYFKDQSAAEIGDKSWLY--LRTLKQEEETHIRNEQVRQRAKECSQALSLI 191 Query: 608 IEMGF--------------------IDEKRIAIWGWSYGGYVSSLALASGTGLFKCGIAV 647 +++ ID ++IA+ G S+GG L S F+CGIA+ Sbjct: 192 LDIDHGKPVKNALDLKFDMEQLKDSIDREKIAVIGHSFGGATVIQTL-SEDQRFRCGIAL 250 Query: 648 APVSSWEYYASVYTERFMGLPTK 670 +W + + E + +P Sbjct: 251 ---DAWMF--PLGDEVYSRIPQP 268 >1LLF-A nrPDB Length = 534 Score = 40.6 bits (93), Expect = 0.003, Method: Composition-based stats. Identities = 36/175 (20%), Positives = 63/175 (36%), Gaps = 20/175 (11%) Query: 487 ILEENKELENALKNIQLPKEEIKKLEVDEITLWYKMILPPQFDRSKKYPLLIQVYGGPCS 546 EEN + AL + K L E L ++ PP P+++ ++GG Sbjct: 68 TFEENLG-KTALDLVMQSKVFQAVLPQSEDCLTINVVRPPGTKAGANLPVMLWIFGGGFE 126 Query: 547 QSVRSVFAVNWISYLASKEG--MVIALVDGR-GTAFQ--GDKLLYAVYRKLGVYEVEDQI 601 ++F + + G ++ V+ R + GD + G ++DQ Sbjct: 127 IGSPTIFPPAQMVTKSVLMGKPIIHVAVNYRVASWGFLAGDDIKAEGSGNAG---LKDQR 183 Query: 602 TAVRKFIE--MGF-IDEKRIAIWGWSYGGYVSSLALA--------SGTGLFKCGI 645 ++ + GF D ++ I+G S G L G LF+ GI Sbjct: 184 LGMQWVADNIAGFGGDPSKVTIFGESAGSMSVLCHLIWNDGDNTYKGKPLFRAGI 238 >3E4D-A nrPDB Length = 278 Score = 40.6 bits (93), Expect = 0.003, Method: Composition-based stats. Identities = 37/193 (19%), Positives = 69/193 (35%), Gaps = 38/193 (19%) Query: 535 PLLIQVYGGPCSQSVRSVFAVNWISYLASKEGMVIALVD-----------------GRGT 577 P++ + G C+ +V +AS+ G+V+ D G+G Sbjct: 45 PVVWYLSGLTCTH--ANVMEKGEYRRMASELGLVVVCPDTSPRGNDVPDELTNWQMGKGA 102 Query: 578 AFQGDKLLY--AVYRKLGVYEVEDQITAVRKFIEMGFIDEKRIAIWGWSYGGYVSSLALA 635 F D + + ++ Y E+ + + D R +I+G S GG+ + Sbjct: 103 GFYLDATEEPWSEHYQMYSYVTEELPALIGQHFR---ADMSRQSIFGHSMGGHGAMTIAL 159 Query: 636 SGTGLFKCGIAVAPVS-----SWEYYASVYTERFMGLPTKDDNLEHYKNSTVMARAE-YF 689 FK A AP+ W A E+++G + ++ + E Sbjct: 160 KNPERFKSCSAFAPIVAPSSADWSEPA---LEKYLGA-----DRAAWRRYDACSLVEDGA 211 Query: 690 RNVDYLLIHGTAD 702 R ++L+ G AD Sbjct: 212 RFPEFLIDQGKAD 224 >4PF1-A nrPDB Length = 626 Score = 40.2 bits (92), Expect = 0.004, Method: Composition-based stats. Identities = 20/104 (19%), Positives = 33/104 (31%), Gaps = 10/104 (9%) Query: 562 ASKEGMVIALVDGRGTAFQGDKLLYAVYRKL-------GVYEVEDQITAVRKFIEMGFID 614 S +I D RG G + Y + + L G D + ++ Sbjct: 94 TSAARYIIVYQDVRG--KYGSEGGYMMNKPLTGPLNTTGTDHSTDTYDTIDWLVKNIPES 151 Query: 615 EKRIAIWGWSYGGYVSSLALASGTGLFKCGIAVAPVSS-WEYYA 657 R+A G SY GY + + + K + A + W Sbjct: 152 NGRVAAIGGSYEGYTTLMCTINPHPALKAVVPFASMVDGWMGDD 195 >1MPX-A nrPDB Length = 615 Score = 39.8 bits (91), Expect = 0.005, Method: Composition-based stats. Identities = 28/167 (16%), Positives = 59/167 (35%), Gaps = 19/167 (11%) Query: 505 KEEIKKLEVDEITLWYKMILPPQFDRSKKYPLLIQVYGGPCSQSVRSVFAVNWISYLASK 564 K E+ D + L ++LP +K P+++ S + + + L++ Sbjct: 25 KREVMIPMRDGVKLHTVIVLP---KGAKNAPIVLTRTPYDASGRTERLASPHMKDLLSAG 81 Query: 565 E------GMVIALVDGRGTAFQGDK----LLYAVYRKLGVYEVE---DQITAVRKFIEMG 611 + G + D RG G + + + L EV+ D + ++ Sbjct: 82 DDVFVEGGYIRVFQDVRG--KYGSEGDYVMTRPLRGPLNPSEVDHATDAWDTIDWLVKNV 139 Query: 612 FIDEKRIAIWGWSYGGYVSSLALASGTGLFKCGIAVAPVSS-WEYYA 657 ++ + G SY G+ +AL + K + +P+ W Sbjct: 140 SESNGKVGMIGSSYEGFTVVMALTNPHPALKVAVPESPMIDGWMGDD 186 >6AGQ-A nrPDB Length = 321 Score = 39.8 bits (91), Expect = 0.005, Method: Composition-based stats. Identities = 49/306 (16%), Positives = 88/306 (28%), Gaps = 52/306 (16%) Query: 480 RTDQEIKILEENKELENALKNIQLPKEEIKKLEVDEITLWYKMILPPQFDRSKKYPLLIQ 539 + + + N + LK+I + + I WY + P + P+L++ Sbjct: 35 SNQKPLHA-QVNLVQDYPLKSISIYDVVYDGADGTPIHGWY--VTPKGEHQPGSLPVLVK 91 Query: 540 VYGGPCSQSVRSVFAVNWISYLASKEGMVIALVDGRGTAF---------QG--DKLLYAV 588 +G S + + + + GM +D RG QG + Sbjct: 92 YHG----YSGNRGYPNELLQW--ASMGMAALAIDVRGQGGVTPDRAEYPQGGIPGWMTLG 145 Query: 589 YRKLGVYEVE----DQITAVRKFIEMGFIDEKRIAIWGWSYGGYVSSLALA--SGTGL-- 640 Y + D I A+ +D RIA++G S GG ++ A S L Sbjct: 146 ILDPASYYYKQVYLDCIRALDFVCSREEVDASRIAVYGGSQGGGLALAAAGLDSRPKLAL 205 Query: 641 --------FKCGI---AVAPVSSWEYYASVYTERFMGLPTKDDNLEHYKNSTV---MARA 686 F+ + A P + + Y P + Y+ + M A Sbjct: 206 PVFPFLCHFRRSVEIHASGPYVEIKNWFRRYD------PEHRQEEQVYRTLSYFDGMNMA 259 Query: 687 EYFRNVDYLLIHGTADDNVHFQNSAQIAKALVNAQVDFQAMWYSDQNHGLSGLSTNHLYT 746 + + I D L + Y D H + Sbjct: 260 SRIKARTLMAI-TLQDITCPPSTCFAAYNHLAG---PKEVRLYHDYGHEGLPFHEEAMMR 315 Query: 747 HMTHFL 752 + +L Sbjct: 316 FIEAYL 321 >3N0T-A nrPDB Length = 469 Score = 39.4 bits (90), Expect = 0.007, Method: Composition-based stats. Identities = 32/152 (21%), Positives = 56/152 (36%), Gaps = 14/152 (9%) Query: 561 LASKEGMVIALVDGR---GTAFQGDKLLYAVYRKLGVYE--VEDQITAVRKFIE-MGFID 614 LA++ G ++ + R + G + + +L E + D +R +G D Sbjct: 71 LAAERGALLVFAEHRYYGKSLPFGAQSTQRGHTELLTVEQALADFAELLRALRRDLGAQD 130 Query: 615 EKRIAIWGWSYGGYVSSLALASGTGLFKCGIAV-APV-SSWEYYASVYTERFMGLPTKDD 672 IA +G SYGG +S+ L +A APV + S R + + Sbjct: 131 APAIA-FGGSYGGMLSAYLRMKYPHLVAGALAASAPVLAVAGLGDSNQFFRDVTADFEGQ 189 Query: 673 NLEHYKNSTVMARAEYFRNVDYLLIHGTADDN 704 + + + E FR + L + G D Sbjct: 190 SPKCTQGVR-----EAFRQIKDLFLQGAYDTV 216 >5L2P-A nrPDB Length = 306 Score = 39.0 bits (89), Expect = 0.008, Method: Composition-based stats. Identities = 53/298 (17%), Positives = 100/298 (33%), Gaps = 57/298 (19%) Query: 491 NKELENALKNIQLPKEEIKKLEVDEITLWYKMILPPQFDRSKKYPLLIQVYGGPCSQSVR 550 N+ L A+ + + K+++++ L ++ P + L++ +GG Sbjct: 35 NELLAKAVPKDPVGETRDMKIKLEDYELPIRIYSPI---KRTNNGLVMHFHGG------- 84 Query: 551 SVFAVNWISY-------LASKEGMVIALVDGRGTAFQGDKLLYAVYRKLGVYEVEDQITA 603 + + I L++ + VD R K AVY D A Sbjct: 85 -AWILGSIETEDAISRILSNSCECTVISVDYRLAPEY--KFPTAVY---------DCFNA 132 Query: 604 VRKFI----EMGFIDEKRIAIWGWSYGG-YVSSLALASGTGLFKCGIAVAPVSSWEYYA- 657 + E+G ID+ +IA +G S GG V++ +L + K A PV + Y Sbjct: 133 IVWARDNAGELG-IDKDKIATFGISAGGNLVAATSLLARDNKLKL-TAQVPVVPFVYLDL 190 Query: 658 -SVYTERF-------MGLPTKDDNLEHYKNSTVMAR-------AEYFRNVDYLLIHGTA- 701 S R+ + LP + ++ + AE N+ ++ Sbjct: 191 ASKSMNRYRKGYFLDINLPVDYGVKMYIRDEKDLYNPLFSPLIAEDLSNLPQAIVVTAEY 250 Query: 702 DDNVHFQNSAQIAKALVNAQVDFQAMWYSDQNHGL--SGLSTNHLYTHMTHFLKQCFS 757 D A L+ + V + + H S ++ + + LK F Sbjct: 251 DP--LRDQGEAYAYRLMESGVPTLSFRVNGNVHAFLGSPRTSRQVTVMIGALLKDIFK 306 >5DWD-A nrPDB Length = 240 Score = 38.7 bits (88), Expect = 0.009, Method: Composition-based stats. Identities = 17/71 (23%), Positives = 26/71 (36%), Gaps = 4/71 (5%) Query: 686 AEYFRNVDYLLIHGTADDNVHFQNSAQIAKALVNAQVDFQAMWYSDQNHGLSGLSTNHLY 745 AE LLIHG DD V S L++ +D + H ++ + Sbjct: 174 AEIASKPPVLLIHGDLDDVVPVIGSETALPKLIDLGIDARLHISQGSGHTIAQDGLD--- 230 Query: 746 THMTHFLKQCF 756 T FL++ Sbjct: 231 -TATAFLREIL 240 >2JBW-A nrPDB Length = 386 Score = 38.7 bits (88), Expect = 0.010, Method: Composition-based stats. Identities = 39/207 (18%), Positives = 74/207 (35%), Gaps = 21/207 (10%) Query: 504 PKEEIKKLEVDEITLWYKMILPPQFDRSKKYPLLIQVYGGPCSQSVRSVFAVNWISYLAS 563 P E +L VD I + + +P +P +I + GG S S + L Sbjct: 125 PPAERHELVVDGIPMPVYVRIPEGPGP---HPAVIML-GGLESTKEESF----QMENLVL 176 Query: 564 KEGMVIALVDGRGTAFQGDKLLYAVYRKLGVYEVEDQITAVRKFIEMGFIDEKRIAIWGW 623 GM A DG QG+ Y+++ + V ++ I I + G Sbjct: 177 DRGMATATFDG---PGQGEMFE---YKRIAGDYEKYTSAVVDLLTKLEAIRNDAIGVLGR 230 Query: 624 SYGGYVSSLALASGTGLFKCGIAVAPVSSWEYYA-----SVYTERFMGLPTKDDNLEHYK 678 S GG + + A L C I+ S +Y+ + + +++ + + Sbjct: 231 SLGGNYALKSAACEPRLAAC-ISWGGFSDLDYWDLETPLTKESWKYVSKVDTLEEARLHV 289 Query: 679 NSTVMARAEYFR-NVDYLLIHGTADDN 704 ++ + R + ++HG D+ Sbjct: 290 HAALETRDVLSQIACPTYILHGVHDEV 316 >1GZ7-A nrPDB Length = 534 Score = 38.3 bits (87), Expect = 0.012, Method: Composition-based stats. Identities = 36/173 (20%), Positives = 64/173 (36%), Gaps = 21/173 (12%) Query: 490 ENKELENALKNIQLPKEEIKKLEVDEITLWYKMILPPQFDRSKKYPLLIQVYGGPCSQSV 549 E+ +NAL + K L DE L +I PP S P+++ ++GG Sbjct: 70 EDTLPKNALDLVLQSKIFQVVLPNDEDCLTINVIRPPGTRASAGLPVMLWIFGGGFELGG 129 Query: 550 RSVFAVNWISYLASKEGMVI--ALVDGR-GTAFQ--GDKLLYAVYRKLGVYEVEDQITAV 604 S+F + + + G + ++ R + G + G + DQ A+ Sbjct: 130 SSLFPGDQMVAKSVLMGKPVIHVSMNYRVASWGFLAGPDIQNEGSGNAG---LHDQRLAM 186 Query: 605 RKFIE--MGF-IDEKRIAIWGWSYGGYVSSLALASGTG---------LFKCGI 645 + + GF D ++ I+G S G +S+ LF+ I Sbjct: 187 QWVADNIAGFGGDPSKVTIYGESAGS-MSTFVHLVWNDGDNTYNGKPLFRAAI 238 >4KRY-A nrPDB Length = 333 Score = 37.9 bits (86), Expect = 0.016, Method: Composition-based stats. Identities = 57/357 (15%), Positives = 93/357 (26%), Gaps = 62/357 (17%) Query: 429 IGSYPPSKKCVTCHLRKERCQYYTASFSDYAKYYALVCYGPGIPISTLHDGRTDQEIKIL 488 + ++ E S K P ++ L Sbjct: 1 MRGSHHHHHHTDPIMKPENKLPVLDLISAEMKTVVNTLQPDLPPWPATGTIAEQRQYYTL 60 Query: 489 E----ENKELENALKNIQLPKEEIKKLEVDEITLWYKMILPPQFDRSKKYP-LLIQVYGG 543 E E A + +P + Y + F P L ++GG Sbjct: 61 ERRFWNAGAPEMATRAYMVPTK-------------YGQVETRLFCPQPDSPATLFYLHGG 107 Query: 544 PCSQSVRSVFAVNWISYLASKEGMVIALVDGRGTAFQGDKLLYAVYRKLGVYEVEDQITA 603 + LAS + +D + + A+ E+ + A Sbjct: 108 GFI-LGNLDTHDRIMRLLASYSQCTVIGIDYTLSPE--ARFPQAI---------EEIVAA 155 Query: 604 VRKFIEMG---FIDEKRIAIWGWSYGGYVSSL-ALASGTGLFKCGIAVAPVSSW-EYYA- 657 F + I+ RI G S G ++ AL CG VA V W Y Sbjct: 156 CCYFHQQAEDYQINMSRIGFAGDSAGAMLALASALWLRDKQIDCG-KVAGVLLWYGLYGL 214 Query: 658 -SVYTERFMG---LPTKDDNLEHYKNSTVMARAEY------------FRNVDYLLIHGTA 701 T R +G +L+ Y+ + + A+ R V I G Sbjct: 215 RDSVTRRLLGGVWDGLTQQDLQMYEEAYLSNDADRESPYYCLFNNDLTREVPPCFIAGAE 274 Query: 702 -DDNVHFQNSAQIAKALVNAQVDFQAMWYSDQNHGLSGLSTNHLYTHMTHFLKQCFS 757 D +S + + L Q + Y H H Y+ M + Sbjct: 275 FDP--LLDDSRLLYQTLAAHQQPCEFKLYPGTLHAF-----LH-YSRMMKTADEALR 323 >1R88-A nrPDB Length = 280 Score = 37.9 bits (86), Expect = 0.018, Method: Composition-based stats. Identities = 26/138 (18%), Positives = 45/138 (32%), Gaps = 23/138 (16%) Query: 519 WYKMILPPQFDRSKKYPLLIQVYGGPCSQSVRSVF-----------AVNWISYLASKEGM 567 Y+ ++ P + P+ GGP + + F A N ++ LA K G+ Sbjct: 10 PYENLMVPSPSMGRDIPVAFLA-GGPHAVYLLDAFNAGPDVSNWVTAGNAMNTLAGK-GI 67 Query: 568 VIALVDGRGTAFQGDKLLYAVYRKLGVY---EVEDQITAVRKFIEMGFIDEKRIAIWGWS 624 + G + ++ + E+ D + A R G A G + Sbjct: 68 SVVAPAGGAYSMY-TNWEQDGSKQWDTFLSAELPDWLAANRGLAPGGH------AAVGAA 120 Query: 625 YGGYVSSLALASGTGLFK 642 GGY + A F Sbjct: 121 QGGYGAMALAAFHPDRFG 138 >3WMR-A nrPDB Length = 315 Score = 37.9 bits (86), Expect = 0.019, Method: Composition-based stats. Identities = 36/199 (18%), Positives = 72/199 (36%), Gaps = 31/199 (15%) Query: 504 PKEEIKKLEVDEITLWYKMILPPQFDRSKKYPLLIQVYGGPCSQSVRSVFAVNWISYLAS 563 P + + WY++ K P ++ ++GGP S +++ + S Sbjct: 20 PPSAKGTVPFGQYRTWYRVT--GDLHSGK--PPVVLLHGGPGSTH-------DYLLAMTS 68 Query: 564 --KEGMVIALVDGRGTAF------QGDKLLYAVYRKLGVYEVEDQITAVRKFIEMGFIDE 615 + G + D G +G+ V ED++ + ++G + Sbjct: 69 LTEAGWPVVHYDQLGNGGSTHLPEKGEDF-------WTVQLFEDELDNL--LNQLGIAGD 119 Query: 616 KRIAIWGWSYGGYVSSLALASGT-GLFKCGIAVAPVSSWEYYASVYTERFMGLPTKDDNL 674 ++G S+GG + S+ A GL +A AP S + + R + P + L Sbjct: 120 --YVLFGQSWGGMLGSVHAARRPAGLRGLVVANAPASMKIWLQEMARLRALLPPDVQETL 177 Query: 675 EHYKNSTVMARAEYFRNVD 693 ++ + EYF + Sbjct: 178 LKHEAARTTDTEEYFHAMR 196 >2D81-A nrPDB Length = 318 Score = 37.5 bits (85), Expect = 0.019, Method: Composition-based stats. Identities = 20/131 (15%), Positives = 49/131 (37%), Gaps = 8/131 (6%) Query: 613 IDEKRIAIWGWSYGGYVSSLALASGTGLFKCG---IAVAPVS--SWEYYASVYTERFMGL 667 ++ +++ G + GGY+++ + + +F G A P +YY S + + Sbjct: 8 VNPNSVSVSGLASGGYMAAQLGVAYSDVFNVGFGVFAGGPYDCARNQYYTSCMYNGYPSI 67 Query: 668 PTKDDNLEHYKNSTVMARAEYFRNVDYLLIHGTADDNVHFQNSAQIAKAL--VNAQVDFQ 725 T N++ + + + + A + G++D V Q+ L + + Sbjct: 68 TTPTANMKSWSGNQIASVA-NLGQRKIYMWTGSSDTTVGPNVMNQLKAQLGNFDNSANVS 126 Query: 726 AMWYSDQNHGL 736 + + H Sbjct: 127 YVTTTGAVHTF 137 >1NX9-A nrPDB Length = 652 Score = 37.5 bits (85), Expect = 0.021, Method: Composition-based stats. Identities = 30/174 (17%), Positives = 59/174 (33%), Gaps = 20/174 (11%) Query: 499 KNIQLPKEEIKKLEVDEITLWYKMILPPQFDRSKKYPLLI----QVYGG-----PCSQSV 549 + K E+ D + L+ +++P ++ P+L+ G P + ++ Sbjct: 31 QQRDYIKREVMVPMRDGVKLYTVIVIPKN---ARNAPILLTRTPYNAKGRANRVPNALTM 87 Query: 550 RSVFAVNWISYLASKEGMVIALVDGRGT-AFQGDKLL----YAVYRKLGVYEVEDQITAV 604 R V ++ + G + D RG QGD ++ + E D V Sbjct: 88 REVLPQGDDVFV--EGGYIRVFQDIRGKYGSQGDYVMTRPPHGPLNPTKTDETTDAWDTV 145 Query: 605 RKFIEMGFIDEKRIAIWGWSYGGYVSSLALASGTGLFKCGIAVAPVSS-WEYYA 657 + R+ + G +Y G+ +AL K +P+ W Sbjct: 146 DWLVHNVPESNGRVGMTGSAYEGFTVVMALLDPHPALKVAAPESPMVDGWMGDD 199 >1XRN-A nrPDB Length = 293 Score = 37.5 bits (85), Expect = 0.023, Method: Composition-based stats. Identities = 32/169 (18%), Positives = 63/169 (37%), Gaps = 24/169 (14%) Query: 512 EVDEITLWYKMILPPQFDRSKKYPLLIQVYGGPCSQSVRSVFAVNWISYLASKEGMVIAL 571 +V+ I ++YK+ P+ +++K L+ ++GGP + + +KEG+ + Sbjct: 11 KVNGIYIYYKLCKAPE-EKAK----LMTMHGGPGMSHDYLLSLRDM-----TKEGITVLF 60 Query: 572 VDGRGTAFQGDKLLYAVYRKLGVYEVEDQITAVRKFIEMGFIDEKRIAIWGWSYGGYVSS 631 D G + GV E E + +++ + G SYGG ++ Sbjct: 61 YDQFGCGRSEEPDQSKFTIDYGVEEAE--------ALRSKLFGNEKVFLMGSSYGGALAL 112 Query: 632 LALASGTGLFKCGIAVAPVSSWEYYASVYTERFMGLPTKDDNLEHYKNS 680 K I +SS T + M D+ Y+++ Sbjct: 113 AYAVKYQDHLKGLIVSGGLSSVPL-----TVKEMN-RLIDELPAKYRDA 155 >4IQ4-A nrPDB Length = 456 Score = 37.1 bits (84), Expect = 0.029, Method: Composition-based stats. Identities = 50/305 (16%), Positives = 99/305 (32%), Gaps = 76/305 (24%) Query: 503 LPKEEIKKLEVDEITLWYKMILPPQFDRSKKYPLLIQVYGGPCSQSVRSVFAVNWISYLA 562 +P + + I L+Y+ D P+++ ++G P S + + L Sbjct: 1 MPFITVGQENSTSIDLYYE-------DHGTGTPVVL-IHGFPLSGH---SWERQSAALLD 49 Query: 563 SKEGMVIALVDGRG-------TAFQG-DKLLYAVYRKLGVYEVEDQI---------TAVR 605 + G + D RG T D + L +++D + R Sbjct: 50 A--GYRVITYDRRGFGQSSQPTTGYDYDTFAADLNTVLETLDLQDAVLVGFSMGTGEVAR 107 Query: 606 KFIEMGFIDEKRIAIWGWSYGGYVSSL--ALASGTG---------LFKCGIAVAPVSSWE 654 G +A +++SL L F +A + Sbjct: 108 YVSSYGTARIAAVA--------FLASLEPFLLKTDDNPDGAAPQEFFDGIVAAVKADRYA 159 Query: 655 YYASVYTERF-----MGLPTKDDNLEHYKNSTVMA----------------RAEYFR-NV 692 +Y + + + +G ++ + + N+ RA+ R +V Sbjct: 160 FYTGFFNDFYNLDENLGTRISEEAVRNSWNTAASGGFFAAAAAPTTWYTDFRADIPRIDV 219 Query: 693 DYLLIHGTADDNVHFQNSAQ-IAKALVNAQVDFQAMWYSDQNHGLSGLSTNHLYTHMTHF 751 L++HGT D + +N+A+ KAL +A + + HGL + T + F Sbjct: 220 PALILHGTGDRTLPIENTARVFHKALPSA----EYVEVEGAPHGLLWTHAEEVNTALLAF 275 Query: 752 LKQCF 756 L + Sbjct: 276 LAKAQ 280 >3FNB-A nrPDB Length = 405 Score = 37.1 bits (84), Expect = 0.031, Method: Composition-based stats. Identities = 36/198 (18%), Positives = 65/198 (32%), Gaps = 35/198 (17%) Query: 465 VCYGPGIPISTLHDGRTDQEIKILEENKELEN----ALKNIQLPKEEIKKLEVDEITLWY 520 + + I ++ + +E + +E A+ N ++P + I+ E+ Y Sbjct: 91 LYFSACFSIRAALQFTDPKDSEFMENFRRMEKLFMLAVDNSKIPLKSIEVPFEGELLPGY 150 Query: 521 KMILPPQFDRSKKYPLLIQVYGGPCS------QSVRSVFAVNWISYLASKEGMVIALVDG 574 +I K LI V GG S S + ++ + G Sbjct: 151 AII-----SEDKAQDTLIVVGGGDTSREDLFYMLGYSGWEHDYNVLMVDLPGQG------ 199 Query: 575 RGTAFQGDKLLYAVYRKLGVYEVEDQITAVRKFIEMGFIDEKRIAIWGWSYGGYVSSLAL 634 QG D A+ ++ ++IAI G+S GGY ++ A+ Sbjct: 200 -KNPNQGLHFEV------------DARAAISAILDWYQAPTEKIAIAGFSGGGYFTAQAV 246 Query: 635 ASGTGLFKCGIAVAPVSS 652 K IA P+ Sbjct: 247 -EKDKRIKAWIASTPIYD 263 >2W6C-X nrPDB Length = 586 Score = 36.3 bits (82), Expect = 0.044, Method: Composition-based stats. Identities = 37/159 (23%), Positives = 62/159 (38%), Gaps = 11/159 (6%) Query: 512 EVDEITLWYKMILPPQFDRSKKYPLLIQVYGGPCSQSVRSVFAVNWISYLASKEGMVIAL 571 E+ E L+ + +P +S +++ +YGG S S V YLA E +V+ Sbjct: 110 EMSEDCLYLNIWVPSPRPKSTT--VMVWIYGG-GFYSGSSTLDVYNGKYLAYTEEVVLVS 166 Query: 572 VDGRGTAFQGDKLLYAVYRKLGVYEVEDQITAVRKFIEMGFI---DEKRIAIWGWSYGGY 628 + R G L+ G + DQ A++ + D K + I+G S GG Sbjct: 167 LSYR-VGAFGFLALHGSQEAPGNVGLLDQRMALQWVHDNIQFFGGDPKTVTIFGESAGGA 225 Query: 629 VSSLALASGT--GLFKCGI--AVAPVSSWEYYASVYTER 663 + + S LF+ I + +P W + R Sbjct: 226 SVGMHILSPGSRDLFRRAILQSGSPNCPWASVSVAEGRR 264 >6EMI-A nrPDB Length = 532 Score = 36.3 bits (82), Expect = 0.048, Method: Composition-based stats. Identities = 33/151 (21%), Positives = 61/151 (40%), Gaps = 18/151 (11%) Query: 511 LEVDEITLWYKMILPPQFDRSKKYPLLIQVYGGPCSQSVRSVFAVNWISYLASKEGMVIA 570 ++ E L+ + +P + K +++ +YGG Q+ S V +LA E +++ Sbjct: 89 TDLSEDCLYLNVWIPAP--KPKNATVMVWIYGG-GFQTGTSSLPVYDGKFLARVERVIVV 145 Query: 571 LVDGR-GT-AFQGDKLLYAVYRKLGVYEVEDQITAVRKFIEMGFI---DEKRIAIWGWSY 625 ++ R G F +G++ DQ A++ + D R+ ++G S Sbjct: 146 SMNYRVGALGFLALPGNPEAPGNMGLF---DQQLALKWVQDNIAAFGGDPNRVTLFGESA 202 Query: 626 GGYVSSLAL---ASGT----GLFKCGIAVAP 649 G SL L S + + G A AP Sbjct: 203 GAASVSLHLLSPGSHPLFTRAILQSGSANAP 233 >3CN7-A nrPDB Length = 226 Score = 36.0 bits (81), Expect = 0.056, Method: Composition-based stats. Identities = 35/147 (23%), Positives = 50/147 (34%), Gaps = 33/147 (22%) Query: 598 EDQITA----VRKFIEMGFID---EKRIAIWGWSYGGYVSSLALASGTGLFKCGIAVAPV 650 EDQ+ A V I+ +RI + G+S GG V T + + V Sbjct: 91 EDQLNASADQVIALIDEQRAKGIAAERIILAGFSQGGAVVL-----HTAFRRYAQPLGGV 145 Query: 651 SSWEYYASVYTERFMGLPTKDDNLEHYKNSTVMARAEYFRNVDYLLIHGTADDNVHFQNS 710 + YA PT DD +A E + + L +HG+ DD V Sbjct: 146 LALSTYA----------PTFDD----------LALDERHKRIPVLHLHGSQDDVVDPALG 185 Query: 711 AQIAKALVNAQVDFQAMWYSDQNHGLS 737 AL V+ Y H +S Sbjct: 186 RAAHDALQAQGVEVGWHDYP-MGHEVS 211 >4ZWN-A nrPDB Length = 334 Score = 36.0 bits (81), Expect = 0.059, Method: Composition-based stats. Identities = 20/121 (16%), Positives = 47/121 (38%), Gaps = 12/121 (9%) Query: 644 GIAVAPVSSWEYYASVYTERFMGLP----------TKDDNLEHYKNSTVMARAEYFRNVD 693 G+ + ++S + Y + M +P + YKN + + ++ Sbjct: 204 GLDLKGITSDKAYRAFLGSDPMSVPLYGSFRQIHDFMQRGAKLYKNENNYIQKNFAKDKP 263 Query: 694 YLLIHGTADDNVHFQNSAQIAKALVNAQVDFQAMWYSDQNHGLSGLSTNHLYTHMTHFLK 753 +++HG D + S + + +A D + Y H + L T+ ++ + + +K Sbjct: 264 VIIMHGQDDTINDPKGSEKFIRDCPSA--DKELKLYPGARHSIFSLETDKVFNTVFNDMK 321 Query: 754 Q 754 Q Sbjct: 322 Q 322 >1DIN-A nrPDB Length = 236 Score = 36.0 bits (81), Expect = 0.060, Method: Composition-based stats. Identities = 36/217 (16%), Positives = 64/217 (29%), Gaps = 48/217 (22%) Query: 535 PLLIQVYGGPCSQSVRSVFAVNWISYLASKEGMVIALVD--GRGTAF-----QGDKLLYA 587 P+++ + F +S+L +G D R Q ++ Sbjct: 29 PVIVIA----QEIFGVNAFMRETVSWLVD-QGYAAVCPDLYARQAPGTALDPQDERQREQ 83 Query: 588 VYRKLGVYEVE----DQITAVRKFIEMGFIDEKRIAIWGWSYGGYVSSLALASGTGLFKC 643 Y+ +++E D A+R + ++ + G+ GG ++ L A G Sbjct: 84 AYKLWQAFDMEAGVGDLEAAIRYARHQPY-SNGKVGLVGYCLGGALAFLVAAKG------ 136 Query: 644 GIAVAPVSSWEYYASVYTERFMGLPTKDDNLEHYKNSTVMARAEYFRNVDYLLIHGTADD 703 Y +R +G + K V A L H D Sbjct: 137 ----------------YVDRAVGYYGVGLEKQLNKVPEVKHPA---------LFHMGGQD 171 Query: 704 NVHFQNSAQIAKALVNAQVDFQAMWYSDQNHGLSGLS 740 + S Q+ A Q WY + H + S Sbjct: 172 HFVPAPSRQLITEGFGANPLLQVHWYEEAGHSFARTS 208 >1BRO-A nrPDB Length = 277 Score = 35.2 bits (79), Expect = 0.11, Method: Composition-based stats. Identities = 18/64 (28%), Positives = 30/64 (46%), Gaps = 5/64 (7%) Query: 692 VDYLLIHGTADDNVHFQNSAQ-IAKALVNAQVDFQAMWYSDQNHGLSGLSTNHLYTHMTH 750 V L++HGT D + +N+A+ KAL +A + + HGL + T + Sbjct: 218 VPALILHGTGDRTLPIENTARVFHKALPSA----EYVEVEGAPHGLLWTHAEEVNTALLA 273 Query: 751 FLKQ 754 FL + Sbjct: 274 FLAK 277 >5CXX-A nrPDB Length = 275 Score = 35.2 bits (79), Expect = 0.11, Method: Composition-based stats. Identities = 13/50 (26%), Positives = 25/50 (50%), Gaps = 2/50 (4%) Query: 495 ENALKNIQLP--KEEIKKLEVDEITLWYKMILPPQFDRSKKYPLLIQVYG 542 + ++ P K+ +V E +ILP +D +KKYP++ ++G Sbjct: 15 RTKQEGVEYPTAKKITYYSKVTETERKMNVILPVGYDENKKYPVVYYLHG 64 >3HLK-A nrPDB Length = 446 Score = 35.2 bits (79), Expect = 0.12, Method: Composition-based stats. Identities = 46/288 (15%), Positives = 89/288 (30%), Gaps = 54/288 (18%) Query: 476 LHDGRTDQEIKILEENKELENALKNIQLPKEEIKKLEVDEITLWYKMILPPQFDRSKKYP 535 + DG ++L + + L P + + V + + LPP+ +P Sbjct: 125 VLDGHDPDPGRLLCQTRHERYFLP----PGVRREPVRVGRVRG--TLFLPPEPGP---FP 175 Query: 536 LLIQVYGGPCSQSVRSVFAVNWISYLASKEGMVIALVDGRGTAFQGDKLLYAVYRKLGVY 595 ++ ++G + + + L + +G + + A+ + L L + Sbjct: 176 GIVDMFG-------TGGGLLEYRASLLAGKGFAVMAL-----AYYNYEDLPKTMETLHLE 223 Query: 596 EVEDQITAVRKFIEMGFIDEKRIAIWGWSYGGYVSSLALASGTGLFKCGIAVAPVSSWEY 655 E A+ + + + + G S GG L L+ + F GI A V + Sbjct: 224 YFE---EAMNYLLSHPEVKGPGVGLLGISKGG---ELCLSMAS--FLKGITAAVVINGSV 275 Query: 656 YASVYTERFMG--LPTKDDNLEHYK--------------------NSTVMARAEYFRNVD 693 T R+ G LP N K + E + Sbjct: 276 ANVGGTLRYKGETLPPVGVNRNRIKVTKDGYADIVDVLNSPLEGPDQKSFIPVERAESTF 335 Query: 694 YLLIHGTADDNVHFQ-NSAQIAKALVNAQ-VDFQAMWYSDQNHGLSGL 739 L+ G D N + + + K L Q + Y + H + Sbjct: 336 LFLV-GQDDHNWKSEFYANEACKRLQAHGRRKPQIICYPETGHYIEPP 382 >1AUO-A nrPDB Length = 218 Score = 34.8 bits (78), Expect = 0.16, Method: Composition-based stats. Identities = 31/147 (21%), Positives = 47/147 (31%), Gaps = 35/147 (23%) Query: 597 VEDQITAVRKFIEMGFIDEKRIAIWGWSYGG---YVSSLALASGTGLFKCGIAVAPVSSW 653 V D I A ++ ID RI + G+S GG + ++ G + V + Sbjct: 91 VTDLIEAQKRTG----IDASRIFLAGFSQGGAVVFHTAFINWQGP--------LGGVIAL 138 Query: 654 EYYASVYTERFMGLPTKDDNLEHYKNSTVMARAEYFRNVDYLLIHGTADDNVHFQNSAQI 713 YA PT D LE + + + L +HG DD V Sbjct: 139 STYA----------PTFGDELE---------LSASQQRIPALCLHGQYDDVVQNAMGRSA 179 Query: 714 AKALVNAQVDFQAMWYSDQNHGLSGLS 740 + L + V Y H + Sbjct: 180 FEHLKSRGVTVTWQEYP-MGHEVLPQE 205 >1LNS-A nrPDB Length = 763 Score = 34.4 bits (77), Expect = 0.20, Method: Composition-based stats. Identities = 35/176 (19%), Positives = 56/176 (31%), Gaps = 47/176 (26%) Query: 617 RIAIWGWSYGGYVSSLALASGTGLFKCGIAVAPVSSWEYY-------------------- 656 ++A+ G SY G ++ A +G + +A A +SSW Y Sbjct: 341 KVAMTGKSYLGTMAYGAATTGVEGLELILAEAGISSWYNYYRENGLVRSPGGFPGEDLDV 400 Query: 657 --ASVYTERFMGLPTKDDNLEHYKNSTVMARAEYFRNVDY-------------------- 694 A Y+ G N E+ K M A ++ DY Sbjct: 401 LAALTYSRNLDGADFLKGNAEYEKRLAEMTAALDRKSGDYNQFWHDRNYLINTDKVKADV 460 Query: 695 LLIHGTADDNVHFQNSAQIAKALVNAQVDFQAM-----WYSDQNHGLSGLSTNHLY 745 L++HG D NV + + KAL + Y + + T + Y Sbjct: 461 LIVHGLQDWNVTPEQAYNFWKALPEGHAKHAFLHRGAHIYMNSWQSIDFSETINAY 516 >5BPT-A nrPDB Length = 741 Score = 34.0 bits (76), Expect = 0.26, Method: Composition-based stats. Identities = 21/100 (21%), Positives = 31/100 (31%), Gaps = 14/100 (14%) Query: 141 VRGNELPRPIQYLCWSPVGSKLAYVYQNNIYLKQRPGDPPFQITFNGRENKIFNGIPDWV 200 V +LP I +L WSP +A V N Q ++ N Sbjct: 7 VGEKQLPHEIIFLAWSPKRDLIALV--NKAGEVLLHRLANIQRVWSLPPN---------- 54 Query: 201 YEEEMLATKYALWWSPNGKFLAYAEFNDTDIPVIAYSYYG 240 E L W P+GK LA+ + + + Sbjct: 55 --ENTGKEVTCLAWRPDGKILAFGLADTKKVILCDVEKPE 92 >3FOB-A nrPDB Length = 281 Score = 33.6 bits (75), Expect = 0.29, Method: Composition-based stats. Identities = 16/64 (25%), Positives = 26/64 (40%), Gaps = 3/64 (4%) Query: 691 NVDYLLIHGTADDNVHFQNSAQIAKALVNAQVDFQAMWYSDQNHGLSGLSTNHLYTHMTH 750 N+ L+IHG +D V F+ S ++ A + + HGL+ + Sbjct: 221 NIPTLIIHGDSDATVPFEYSGKLT---HEAIPNSKVALIKGGPHGLNATHAKEFNEALLL 277 Query: 751 FLKQ 754 FLK Sbjct: 278 FLKD 281 >6BX3-A nrPDB Length = 314 Score = 33.6 bits (75), Expect = 0.34, Method: Composition-based stats. Identities = 21/92 (22%), Positives = 29/92 (31%), Gaps = 22/92 (23%) Query: 149 PIQYLCWSPVGSKLAYVYQNNI--YLKQRPGDPPFQITFNGRENKIFNGIPDWVYEEEML 206 SP G LA NI Y R +T + R Sbjct: 14 KATCAKISPDGQFLAITQGLNILIYDINRRTVSQTLVTSHARPFSELC------------ 61 Query: 207 ATKYALWWSPNGKFLAYAEFNDTDIPVIAYSY 238 WSP+G+ +A A +D + +I SY Sbjct: 62 -------WSPDGQCIATA-SDDFSVEIIHLSY 85 Score = 32.5 bits (72), Expect = 0.66, Method: Composition-based stats. Identities = 19/72 (26%), Positives = 28/72 (38%), Gaps = 12/72 (16%) Query: 94 TMKSVNASNYGLSPDRQFVYLESDYSKLWRYSYTATYYIYDLSNGEFVRG--NELPRPIQ 151 T + A+ +SPD QF+ + IYD++ + RP Sbjct: 9 TQNGLKATCAKISPDGQFLAITQ----------GLNILIYDINRRTVSQTLVTSHARPFS 58 Query: 152 YLCWSPVGSKLA 163 LCWSP G +A Sbjct: 59 ELCWSPDGQCIA 70 >5BPW-A nrPDB Length = 843 Score = 33.6 bits (75), Expect = 0.34, Method: Composition-based stats. Identities = 22/107 (20%), Positives = 37/107 (34%), Gaps = 16/107 (14%) Query: 135 LSNGEFVRGNELPRPIQYLCWSPVGSKLAYVYQNNIYLKQRPGDPP-FQITFNGRENKIF 193 + V +LP+ I +L WSP +A L G+ ++ F Sbjct: 8 FPSFRVVGEKQLPQEIIFLVWSPKRDLIA--------LANTAGEVLLHRLAS-------F 52 Query: 194 NGIPDWVYEEEMLATKYALWWSPNGKFLAYAEFNDTDIPVIAYSYYG 240 + + + E L W P+GK LA+A + I + Sbjct: 53 HRVWSFPPNENTGKEVTCLAWRPDGKLLAFALADTKKIVLCDVEKPE 99 >3MGA-A nrPDB Length = 407 Score = 32.9 bits (73), Expect = 0.49, Method: Composition-based stats. Identities = 24/124 (19%), Positives = 43/124 (34%), Gaps = 19/124 (15%) Query: 594 VYEVEDQITAVRKFIEMGFIDEKRIAIWGWSYGGYVSSLALASGTGLFKCGIAVAPVSSW 653 E+ Q+ AV F + D R + G S+GG + A + F C ++ + W Sbjct: 263 QQELLPQVRAVTPFSD----DAGRTVVAGQSFGGLSALYAGLNWPTRFGCVLSQSGSFWW 318 Query: 654 EYYASVYTERFMGLPTKDDNLEHYKNSTVMARAEYFRNVDYLLIHGTADDNVHFQNSAQI 713 P + E + + A R + +L G + + FQ + + Sbjct: 319 --------------PHRITPPEGEVITRLKTGALCARGLRIVLEAGVREP-IVFQANQAL 363 Query: 714 AKAL 717 L Sbjct: 364 YAQL 367 >5TOS-A nrPDB Length = 395 Score = 32.5 bits (72), Expect = 0.65, Method: Composition-based stats. Identities = 15/116 (12%), Positives = 45/116 (38%), Gaps = 15/116 (12%) Query: 607 FIEMGFIDEKRIAIWGWSYGGYVSSLALASGTGLFKCGIAVAPVSSWEYYASVYTERFMG 666 ++ ++ + + +G++ Y+SS L + + ++ G+ + +R + Sbjct: 229 MGDLSYVSTRVMGTYGYAAPEYMSSGHLNARSDVYSFGV--------LLLEILSGKRALD 280 Query: 667 L--PTKDDNLEHYKNSTVMARAEYFRNVDYLLIHGTADDNVHFQNSAQIAKALVNA 720 P K++NL + + + + L++ D + + ++A V Sbjct: 281 HNRPAKEENLVDWARPYLTS-----KRKVLLIVDNRLDTQYLPEEAVRMASVAVQC 331 >6EIC-C nrPDB Length = 279 Score = 32.5 bits (72), Expect = 0.79, Method: Composition-based stats. Identities = 38/260 (14%), Positives = 79/260 (30%), Gaps = 55/260 (21%) Query: 536 LLIQVYG-GPCSQSVRSVFAVNWISYLASKEGMVIALVDGRGTAFQGDKLLYAVYRKLGV 594 +++ +G G ++ + ++ G+V +D RG G K + R + Sbjct: 32 VVVLAHGLGEHAR------RYDHVAQRLGAAGLVTYALDHRGHGRSGGK--RVLVRDISE 83 Query: 595 YEVE-DQITAVRKFIEMGFIDEKRIAIWGWSYGGYVSSLALASGTGLFKCGIAVAPVS-- 651 Y + D + + + KRI + G S GG + + + AP Sbjct: 84 YTADFDTLVGI---ATREYPGCKRI-VLGHSMGGGIVFAYGVERPDNYDLMVLSAPAVAA 139 Query: 652 -SWEYYASVYTERFMG-----LP---------TKDDNLEHYKNSTVMARAEYFRNV---- 692 + +G LP ++D + N+ + Sbjct: 140 QDLVSPVVAVAAKLLGVVVPGLPVQELDFTAISRDPEVVQAYNTDPLVHHGRVPAGIGRA 199 Query: 693 -----------------DYLLIHGTADDNVHFQNSAQIAKALVNAQVDFQAMWYSDQNHG 735 L++HGT D + + S ++ + + D Q Y H Sbjct: 200 LLQVGETMPRRAPALTAPLLVLHGTDDRLIPIEGSRRLVECV--GSADVQLKEYPGLYHE 257 Query: 736 -LSGLSTNHLYTHMTHFLKQ 754 + N + + +L + Sbjct: 258 VFNEPERNQVLDDVVAWLTE 277 >5JM6-A nrPDB Length = 519 Score = 32.1 bits (71), Expect = 0.81, Method: Composition-based stats. Identities = 20/181 (11%), Positives = 44/181 (24%), Gaps = 18/181 (9%) Query: 226 FNDTDIPVIAYSYYGDEQYPRTINIPYPKAGAKNPVVRIFIIDTTYPAYVGPQEVPVPA- 284 ++ + P PY NP V ++D + V +PA Sbjct: 36 IDEAPT----VPLEAKDLRPEHFTQPYLDFMTHNPTV-FHVVDYCKQKLLKAGYVELPAR 90 Query: 285 -----MIASSDYYFSWLTWVTDERVCLQWLKRVQNVSVLSICDFREDWQTWDCPKTQEHI 339 + YF+ + + + N + D + Sbjct: 91 DSWTGKLVPGGKYFTTRNGSSIIAFTVGQAYKPGNGIAMIA-------GHIDALTARLKP 143 Query: 340 EESRTGWAGGFFVSTPVFSYDAISYYKIFSDKDGYKHIHYIKDTVENAIQITSGKWEAIN 399 + G + ++ + G + I T + +++ W Sbjct: 144 TSVKPTKEGYVQLGVAQYAGALNETWWDRDLSVGGRVIVKDPKTGKTTVKLVKVDWPVAR 203 Query: 400 I 400 I Sbjct: 204 I 204 >4QWW-A nrPDB Length = 542 Score = 32.1 bits (71), Expect = 0.81, Method: Composition-based stats. Identities = 27/131 (20%), Positives = 48/131 (36%), Gaps = 13/131 (9%) Query: 532 KKYPLLIQVYGGPCSQSVRSVFAVNWISYLASKEGMVIALVDGRGT--AFQGDKLLYAVY 589 K P+L+ +YGG S + V +L + +++ + R F G Sbjct: 107 KDAPVLVWIYGG-GFYSGAASLDVYDGRFLTYTQNVILVSLSYRVGAFGFLGLPGSPEAP 165 Query: 590 RKLGVYEVEDQITAVRKFIEM--GFIDEKR-IAIWGWSYGGYVSSLAL--ASGTGLFKCG 644 +G+ DQ A++ F R + ++G S G + L LF+ Sbjct: 166 GNMGLL---DQRLALQWIQNNIHPFGGNPRAVTVFGESAGAASVGMHLLSTQSRTLFQRA 222 Query: 645 I--AVAPVSSW 653 I + P + W Sbjct: 223 ILQSGGPNAPW 233 >5W8P-A nrPDB Length = 370 Score = 32.1 bits (71), Expect = 0.90, Method: Composition-based stats. Identities = 18/107 (16%), Positives = 31/107 (28%), Gaps = 11/107 (10%) Query: 543 GPCSQSVRSVFAVNWISYLASKEGMVIALVDGRGTAFQGDKLLYAVYRKLGVYEVEDQIT 602 GP + + + L G R G + V DQ+ Sbjct: 79 GPGAAIDTDHWCAVATNVLGGCRGTTGPTSLARDGKPWGSRFPE--------VSVRDQVN 130 Query: 603 A-VRKFIEMGFIDEKRIAIWGWSYGGYVSSLALASGTGLFKCGIAVA 648 A V ++G + A+ G S GG + + + +A Sbjct: 131 ADVAALAQLGITEVA--AVVGGSMGGARALEWAVMHPDAVRAALVLA 175 >4X8E-A nrPDB Length = 447 Score = 32.1 bits (71), Expect = 1.0, Method: Composition-based stats. Identities = 14/59 (23%), Positives = 20/59 (33%), Gaps = 3/59 (5%) Query: 197 PDWVYEEEMLATKYALWWSPNGKFLAYAEFNDTDI--PVIAYSYYGDEQYPRTINIPYP 253 W Y E T +W+P+G + D PV +Y+ E Y P Sbjct: 238 AGWAYRCEAGLT-APQFWNPDGTRTRFGHVEDIPPDEPVQHVTYFEAEAYAAWAGARLP 295 >6QAA-A nrPDB Length = 557 Score = 32.1 bits (71), Expect = 1.1, Method: Composition-based stats. Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 11/131 (8%) Query: 511 LEVDEITLWYKMILPPQFDRSKKYPLLIQVYGGPCSQSVRSVFAVNWISYLASKEGMVIA 570 ++ E L+ + +P + K +LI +YGG Q+ S V +LA E +++ Sbjct: 114 TDLSEDCLYLNVWIPAP--KPKNATVLIWIYGG-GFQTGTSSLHVYDGKFLARVERVIVV 170 Query: 571 LVDGR-GT-AFQGDKLLYAVYRKLGVYEVEDQITAVRKFIEMGFI---DEKRIAIWGWSY 625 ++ R G F +G++ DQ A++ + + K + ++G S Sbjct: 171 SMNYRVGALGFLALPGNPEAPGNMGLF---DQQLALQWVQKNIAAFGGNPKSVTLFGESA 227 Query: 626 GGYVSSLALAS 636 G SL L S Sbjct: 228 GAASVSLHLLS 238 >5J54-A nrPDB Length = 494 Score = 32.1 bits (71), Expect = 1.1, Method: Composition-based stats. Identities = 22/108 (20%), Positives = 37/108 (34%), Gaps = 27/108 (25%) Query: 534 YPLLIQVYGGPCSQSVRSVFAVNWISYLASKEGMVIALVDGRGTAFQGDKLLYAVYRKLG 593 +P V+G P + +W+ +AS G+ V Sbjct: 307 FPFFPDVHGAPFNGMEAMSHPTDWVVDMASN----------------GEDFAGIVKLSDT 350 Query: 594 VYEV---EDQITAVR----KFIEMGFIDEKR-IAIWGWSYGGYVSSLA 633 E +D+ T + F+EM D KR + + G S GG + + Sbjct: 351 AAEFPRIDDRFTGQKTRHGWFLEM---DMKRPVELRGGSAGGLLMNCL 395 >1GQI-A nrPDB Length = 708 Score = 31.7 bits (70), Expect = 1.1, Method: Composition-based stats. Identities = 33/156 (21%), Positives = 53/156 (33%), Gaps = 20/156 (12%) Query: 592 LGVYEVEDQITAVRKFIEMGFIDEKRIAIW------GWSYGGYVSSLALASGTGLFKCGI 645 L + E + A +E I+++ + I G YG + + + L K + Sbjct: 83 LNLGERLQALGAEGYLLEQTRINKRHVVIVAANSDVGVLYGSFHLLRLIQTQHALEKLSL 142 Query: 646 AVAP------VSSWEYYASVYTERFMGLPTKDDNLEHYKNSTVMARAEYFRNVDYLLIHG 699 + AP V+ W+ V + GL D + +Y R L I+G Sbjct: 143 SSAPRLQHRVVNHWDNLNRVVERGYAGLSLWDWGSLPNYLAPRYT--DYARINASLGING 200 Query: 700 T------ADDNVHFQNSAQIAKALVNAQVDFQAMWY 729 T AD V Q AL +A + Y Sbjct: 201 TVINNVNADPRVLSDQFLQKIAALADAFRPYGIKMY 236 >2B20-A nrPDB Length = 403 Score = 31.7 bits (70), Expect = 1.4, Method: Composition-based stats. Identities = 11/44 (25%), Positives = 17/44 (38%), Gaps = 1/44 (2%) Query: 611 GFIDEK-RIAIWGWSYGGYVSSLALASGTGLFKCGIAVAPVSSW 653 F D R + G S+GG + A F C ++ + W Sbjct: 270 PFSDRADRTVVAGQSFGGLSALYAGLHWPERFGCVLSQSGSYWW 313 >4BZF-A nrPDB Length = 324 Score = 31.3 bits (69), Expect = 1.4, Method: Composition-based stats. Identities = 20/108 (18%), Positives = 42/108 (38%), Gaps = 14/108 (12%) Query: 317 VLSICDFREDWQTWDCPKTQEHIEESRTGW-----AGGFFVSTPVFSYDAISYYKIFSDK 371 V+S+ D + Q P+T E ++ T + +S FS+ +Y+ ++K Sbjct: 34 VISLVDKTTNVQLLREPETAESFHDTPTLYGIPILFPPNRISDGTFSFRGRTYHFDINEK 93 Query: 372 DGYKHIHYIKDTVENAIQITSGKWEAINIFRVTQDSLFYSSNEFEEYP 419 D + H+H + KW + + + + + + E P Sbjct: 94 DKHNHLHGF---------LYHEKWNVVTTKQTDEGVIVETEIDLSELP 132 >2IVF-A nrPDB Length = 976 Score = 31.3 bits (69), Expect = 1.7, Method: Composition-based stats. Identities = 14/64 (21%), Positives = 29/64 (45%), Gaps = 5/64 (7%) Query: 129 TYYIYDLSNGEFVRGNE----LPRPIQYLCWSPVGSKLAYVYQNNIYLKQRPGDPPFQIT 184 +Y+Y + NG R + + Y+ ++P+G + + NN+Y +R P ++ Sbjct: 93 KFYVY-VRNGIVWREEQAAQTPACNVDYVDYNPLGCQKGSAFNNNLYGDERVKYPLKRVG 151 Query: 185 FNGR 188 G Sbjct: 152 KRGE 155 >5GQY-A nrPDB Length = 793 Score = 30.9 bits (68), Expect = 2.3, Method: Composition-based stats. Identities = 29/165 (17%), Positives = 53/165 (32%), Gaps = 35/165 (21%) Query: 127 TATYYIYDLSNGEFVRGNELPRPIQYLCWSPVGSKL------AYVYQNNIYLKQRPGDPP 180 + T Y Y++ N E + Y P + + Y + + +L++R P Sbjct: 207 SGTVYKYEIKNSEGHIYEKSDPYGFYREVRPNTASIVVDIDNIYQWHDEEWLEKRRNSDP 266 Query: 181 FQIT--------------FNGRENKIFNGIPDWVYEEEMLATKYALWWSPNGKFLAYAEF 226 + + + + NG D V E W+P +FL+Y E Sbjct: 267 LKQPVSVYEVHLGSWLHGSSAEKMPLLNGEADPVIVSE---------WNPGARFLSYYEL 317 Query: 227 NDTDIPVI------AYSYYGDEQYPRTINIPYPKAGAKNPVVRIF 265 + IP + ++P + Y G +P R Sbjct: 318 AEKLIPYVKDMGYTHIELLPIAEHPFDGSWGYQVTGFYSPTSRFG 362 >3WLA-A nrPDB Length = 336 Score = 30.6 bits (67), Expect = 2.4, Method: Composition-based stats. Identities = 19/83 (22%), Positives = 33/83 (39%), Gaps = 16/83 (19%) Query: 573 DGRGTAFQGDKLLYAVYRKLGVYEVEDQITAVRKFIE----MGFIDEKRIAIWGWSYGGY 628 DGR GDK + D + + + +D KR+ + G S GG Sbjct: 116 DGRAPDASGDKYK---------TDAGDDVRFLEAMVRCVGTKWKLDRKRLFLGGISAGGT 166 Query: 629 VSSLALASGTGLFKCGIAVAPVS 651 +++ AL + + G+ P+S Sbjct: 167 MTNRALLFDSEFWAGGM---PIS 186 >1AZW-A nrPDB Length = 313 Score = 30.6 bits (67), Expect = 2.6, Method: Composition-based stats. Identities = 10/61 (16%), Positives = 20/61 (32%), Gaps = 4/61 (6%) Query: 682 VMARAEYFRNVDYLLIHGTADDNVHFQNSAQIAKALVNAQVDFQAMWYSDQNHGLSGLST 741 ++ A ++ +++HG D Q++ + KA A Q H Sbjct: 246 LLRDAHRIADIPGVIVHGRYDVVCPLQSAWDLHKAWPKA----QLQISPASGHSAFEPEN 301 Query: 742 N 742 Sbjct: 302 V 302 >4NOX-A nrPDB Length = 746 Score = 30.2 bits (66), Expect = 3.4, Method: Composition-based stats. Identities = 23/143 (16%), Positives = 53/143 (37%), Gaps = 6/143 (4%) Query: 93 RTMKSVNASNYGL--SPDRQFVYLESDYSKLWRYSYTATYYIYDLSNGEF--VRGNELPR 148 RT+ + S+ + + ++ ++ D + S T I+ + + + Sbjct: 404 RTLNLFSVSDVKMHWQSEGTYLCVKVDRHSKSKKSQATTLEIFRVKEKGVPVEVVDTIKD 463 Query: 149 PIQYLCWSPVGSKLAYVYQNNIYLKQRPGDPPFQITFNGRENKIFNGIPDWVYEEEM-LA 207 + W P G + + + P ++F E K N + + + + Sbjct: 464 TVINFAWEPKGDRFVIITTPEP-VGATAVPPKTSVSFFCPELKKGNQVGSFKHLRTLEKK 522 Query: 208 TKYALWWSPNGKFLAYAEFNDTD 230 A++WSP G+F+ A ++T Sbjct: 523 NHNAIYWSPKGRFVVIATVHNTQ 545 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.307 0.121 0.304 Lambda K H 0.267 0.0374 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 26,622,624 Number of Sequences: 36641 Number of extensions: 1065434 Number of successful extensions: 3435 Number of sequences better than 10.0: 133 Number of HSP's better than 10.0 without gapping: 92 Number of HSP's successfully gapped in prelim test: 87 Number of HSP's that attempted gapping in prelim test: 3042 Number of HSP's gapped (non-prelim): 227 length of query: 760 length of database: 10,336,785 effective HSP length: 105 effective length of query: 655 effective length of database: 6,489,480 effective search space: 4250609400 effective search space used: 4250609400 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 63 (29.0 bits)