BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q12406 (477 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 4I6M-A nrPDB 993 0.0 3QB0-A nrPDB 105 4e-23 5NBL-C nrPDB 82 4e-16 4PL7-A nrPDB 80 2e-15 1C0F-A nrPDB 80 3e-15 5NW4-V nrPDB 77 1e-14 5MVV-A nrPDB 76 3e-14 4CBX-A nrPDB 76 3e-14 3MN5-A nrPDB 75 9e-14 6F3A-A nrPDB 67 2e-11 3ULE-B nrPDB 48 8e-06 5NW4-X nrPDB 42 5e-04 6HTS-H nrPDB 36 0.039 1K8K-A nrPDB 35 0.052 4AM6-A nrPDB 33 0.29 3DWL-A nrPDB 32 0.83 3FIJ-A nrPDB 31 1.3 4AMG-A nrPDB 31 1.4 4JUK-A nrPDB 30 1.7 4AV2-A nrPDB 30 2.2 4MHI-A nrPDB 30 2.6 3K9V-A nrPDB 29 3.8 5LY3-A nrPDB 29 4.2 3K85-A nrPDB 29 4.2 4I6M-B nrPDB 29 5.1 3WEE-A nrPDB 28 5.8 6GEJ-R nrPDB 28 6.7 5V7X-A nrPDB 28 7.1 >4I6M-A nrPDB Length = 477 Score = 993 bits (2567), Expect = 0.0, Method: Compositional matrix adjust. Identities = 477/477 (100%), Positives = 477/477 (100%) Query: 1 MTLNRKCVVIHNGSHRTVAGFSNVELPQCIIPSSYIKRTDEGGEAEFIFGTYNMIDAAAE 60 MTLNRKCVVIHNGSHRTVAGFSNVELPQCIIPSSYIKRTDEGGEAEFIFGTYNMIDAAAE Sbjct: 1 MTLNRKCVVIHNGSHRTVAGFSNVELPQCIIPSSYIKRTDEGGEAEFIFGTYNMIDAAAE 60 Query: 61 KRNGDEVYTLVDSQGLPYNWDALEMQWRYLYDTQLKVSPEELPLVITMPATNGKPDMAIL 120 KRNGDEVYTLVDSQGLPYNWDALEMQWRYLYDTQLKVSPEELPLVITMPATNGKPDMAIL Sbjct: 61 KRNGDEVYTLVDSQGLPYNWDALEMQWRYLYDTQLKVSPEELPLVITMPATNGKPDMAIL 120 Query: 121 ERYYELAFDKLNVPVFQIVIEPLAIALSMGKSSAFVIDIGASGCNVTPIIDGIVVKNAVV 180 ERYYELAFDKLNVPVFQIVIEPLAIALSMGKSSAFVIDIGASGCNVTPIIDGIVVKNAVV Sbjct: 121 ERYYELAFDKLNVPVFQIVIEPLAIALSMGKSSAFVIDIGASGCNVTPIIDGIVVKNAVV 180 Query: 181 RSKFGGDFLDFQVHERLAPLIKEENDMENMADEQKRSTDVWYEASTWIQQFKSTMLQVSE 240 RSKFGGDFLDFQVHERLAPLIKEENDMENMADEQKRSTDVWYEASTWIQQFKSTMLQVSE Sbjct: 181 RSKFGGDFLDFQVHERLAPLIKEENDMENMADEQKRSTDVWYEASTWIQQFKSTMLQVSE 240 Query: 241 KDLFELERYYKEQADIYAKQQEQLKQMDQQLQYTALTGSPNNPLVQKKNFLFKPLNKTLT 300 KDLFELERYYKEQADIYAKQQEQLKQMDQQLQYTALTGSPNNPLVQKKNFLFKPLNKTLT Sbjct: 241 KDLFELERYYKEQADIYAKQQEQLKQMDQQLQYTALTGSPNNPLVQKKNFLFKPLNKTLT 300 Query: 301 LDLKECYQFAEYLFKPQLISDKFSPEDGLGPLMAKSVKKAGASINSMKANTSTNPNGLGT 360 LDLKECYQFAEYLFKPQLISDKFSPEDGLGPLMAKSVKKAGASINSMKANTSTNPNGLGT Sbjct: 301 LDLKECYQFAEYLFKPQLISDKFSPEDGLGPLMAKSVKKAGASINSMKANTSTNPNGLGT 360 Query: 361 SHINTNVGDNNSTASSSNISPEQVYSLLLTNVIITGSTSLIEGMEQRIIKELSIRFPQYK 420 SHINTNVGDNNSTASSSNISPEQVYSLLLTNVIITGSTSLIEGMEQRIIKELSIRFPQYK Sbjct: 361 SHINTNVGDNNSTASSSNISPEQVYSLLLTNVIITGSTSLIEGMEQRIIKELSIRFPQYK 420 Query: 421 LTTFANQVMMDRKIQGWLGALTMANLPSWSLGKWYSKEDYETLKRDRKQSQATNATN 477 LTTFANQVMMDRKIQGWLGALTMANLPSWSLGKWYSKEDYETLKRDRKQSQATNATN Sbjct: 421 LTTFANQVMMDRKIQGWLGALTMANLPSWSLGKWYSKEDYETLKRDRKQSQATNATN 477 >3QB0-A nrPDB Length = 498 Score = 105 bits (262), Expect = 4e-23, Method: Compositional matrix adjust. Identities = 116/504 (23%), Positives = 212/504 (42%), Gaps = 82/504 (16%) Query: 8 VVIHNGSHRTVAGFSNVELPQCIIPSSYIKRT-DEGGEAEFIFGTYNMIDAAAEKRNGDE 66 VVI GS+ T G+S + PQ I+PS Y K T DEG + F + + R E Sbjct: 26 VVIDPGSYTTNIGYSGSDFPQSILPSVYGKYTADEGNKKIFSEQSIGI------PRKDYE 79 Query: 67 VYTLVDSQGLPYNWDALEMQWRYLYDTQLKV-SPEELPLVITMPATNGKPDMAILERYYE 125 + ++++ GL +WD + QW++ +L + S +P ++T P N + ++ E Sbjct: 80 LKPIIEN-GLVIDWDTAQEQWQWALQNELYLNSNSGIPALLTEPVWNSTENR---KKSLE 135 Query: 126 LAFDKLNVPVFQIVIEPLAIALSMGKSSAFVIDIGASGCNVTPIIDGIVVKNAVVRSKFG 185 + + + + ++ + G+ + V+DIG C+V+PI+DG+ + + R+ Sbjct: 136 VLLEGMQFEACYLAPTSTCVSFAAGRPNCLVVDIGHDTCSVSPIVDGMTLSKSTRRNFIA 195 Query: 186 GDFLDFQVHERLAPLIKEENDMENMADEQKRSTDVWYEASTWIQQFKSTMLQVSEKDLFE 245 G F++ + + L P + + A +Q++ + K T +K L++ Sbjct: 196 GKFINHLIKKALEP----KEIIPLFAIKQRKP-----------EFIKKTFDYEVDKSLYD 240 Query: 246 LER---YYKEQAD--IYAKQQEQLKQMDQQLQYTALTGSPNNPLVQKKNFLFKPLNKTLT 300 +++E + + + L++ +L TA K + P N+ + Sbjct: 241 YANNRGFFQECKETLCHICPTKTLEETKTELSSTA------------KRSIESPWNEEIV 288 Query: 301 LDLKECYQFAEYLFKP-----------------QLISDKFSPEDGLGPL-MAKSVKK--- 339 D + Y FAE LF P + + + P P + KS KK Sbjct: 289 FDNETRYGFAEELFLPKEDDIPANWPRSNSGVVKTWRNDYVPLKRTKPSGVNKSDKKVTP 348 Query: 340 -------AGASINSMKANTSTNPNGLGTSHI---------NTNVGDNNSTASSSNISPEQ 383 A + S AN++ PN G + N +G + SS S Sbjct: 349 TEEKEQEAVSKSTSPAANSADTPNETGKRPLEEEKPPKENNELIGLADLVYSSIMSSDVD 408 Query: 384 VYSLLLTNVIITGSTSLIEGMEQRIIKELSIRFPQYKLTTFANQVMMDRKIQGWLGALTM 443 + + L NV++TG TS I G+ R++ EL+ P K ++R+ Q WLG + Sbjct: 409 LRATLAHNVVLTGGTSSIPGLSDRLMTELNKILPSLKFRILTTGHTIERQYQSWLGGSIL 468 Query: 444 ANLPSWSLGKWYSKEDYETLKRDR 467 +L ++ W K++YE + +R Sbjct: 469 TSLGTFH-QLWVGKKEYEEVGVER 491 >5NBL-C nrPDB Length = 375 Score = 82.4 bits (202), Expect = 4e-16, Method: Compositional matrix adjust. Identities = 56/193 (29%), Positives = 94/193 (48%), Gaps = 19/193 (9%) Query: 7 CVVIHNGSHRTVAGFSNVELPQCIIPSSYIKRTDEG-----GEAEFIFGTYNMIDAAAEK 61 +VI NGS AGF+ + P+ + PS + +G G+ + G D A K Sbjct: 7 ALVIDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGIMVGMGQKDSYVG-----DEAQSK 61 Query: 62 RNGDEVYTLV--DSQGLPYNWDALEMQWRYLYDTQLKVSPEELPLVITMPATNGKPDMAI 119 R + TL G+ NWD +E W + + +L+V+PEE P+++T N K + Sbjct: 62 RG---ILTLRYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPMNPKSNR-- 116 Query: 120 LERYYELAFDKLNVPVFQIVIEPLAIALSMGKSSAFVIDIGASGCNVTPIIDGIVVKNAV 179 E+ ++ F+ NVP F + I+ + S G+++ V+D G +V PI G + +A+ Sbjct: 117 -EKMTQIMFETFNVPAFYVSIQAVLSLYSSGRTTGIVLDSGDGVTHVVPIYAGFSLPHAI 175 Query: 180 VRSKFGG-DFLDF 191 +R G D D+ Sbjct: 176 LRIDLAGRDLTDY 188 Score = 36.6 bits (83), Expect = 0.023, Method: Compositional matrix adjust. Identities = 21/75 (28%), Positives = 42/75 (56%), Gaps = 5/75 (6%) Query: 388 LLTNVIITGSTSLIEGMEQRIIKELSIRFP-QYKLTTFANQVMMDRKIQGWLGALTMANL 446 L N++++G T++ G+ +R+ KE++ P K+ A +RK W+G +A+L Sbjct: 293 LYGNIVMSGGTTMFPGIAERMQKEITALAPSSMKVKIIAPP---ERKYSVWIGGSILASL 349 Query: 447 PSWSLGKWYSKEDYE 461 ++ W SK++Y+ Sbjct: 350 TTFQQ-MWISKQEYD 363 >4PL7-A nrPDB Length = 440 Score = 80.1 bits (196), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 53/193 (27%), Positives = 93/193 (48%), Gaps = 19/193 (9%) Query: 7 CVVIHNGSHRTVAGFSNVELPQCIIPSSYIKRTDEG-----GEAEFIFGTYNMIDAAAEK 61 +VI NGS AG++ + P + PS + +G G+ + G D A K Sbjct: 7 ALVIDNGSGMCKAGYAGDDAPHTVFPSVVGRPRHQGVMVGMGQKDSFVG-----DEAQSK 61 Query: 62 RNGDEVYTLV--DSQGLPYNWDALEMQWRYLYDTQLKVSPEELPLVITMPATNGKPDMAI 119 R + TL G+ NWD +E W + + +L+++PEE P+++T N K + Sbjct: 62 RG---ILTLRYPIEHGIVTNWDDMEKIWHHTFYNELRLAPEEHPVLLTEAPMNPKSNR-- 116 Query: 120 LERYYELAFDKLNVPVFQIVIEPLAIALSMGKSSAFVIDIGASGCNVTPIIDGIVVKNAV 179 E+ ++ F+ NVP F + I+ + + G+++ V+D G +V PI G + +A+ Sbjct: 117 -EKMTQIMFETFNVPAFYVSIQAVLSLYASGRTTGIVLDSGDGVTHVVPIYAGFSLPHAI 175 Query: 180 VRSKFGG-DFLDF 191 +R G D D+ Sbjct: 176 LRIDLAGRDLTDY 188 Score = 37.4 bits (85), Expect = 0.013, Method: Compositional matrix adjust. Identities = 20/74 (27%), Positives = 41/74 (55%), Gaps = 3/74 (4%) Query: 388 LLTNVIITGSTSLIEGMEQRIIKELSIRFPQYKLTTFANQVMMDRKIQGWLGALTMANLP 447 L +N++++G T++ G+ +R+ KEL+ P + +RK W+G +A+L Sbjct: 293 LYSNIVMSGGTTMFPGIAERMQKELTALAPSSMKVKISAPP--ERKYSVWIGGSILASLG 350 Query: 448 SWSLGKWYSKEDYE 461 ++ W SK++Y+ Sbjct: 351 TFQQ-MWISKQEYD 363 >1C0F-A nrPDB Length = 368 Score = 79.7 bits (195), Expect = 3e-15, Method: Compositional matrix adjust. Identities = 52/191 (27%), Positives = 93/191 (48%), Gaps = 16/191 (8%) Query: 6 KCVVIHNGSHRTVAGFSNVELPQCIIPSSYIKRTDEGGEAEFIFGTYNMIDAAAEKRNGD 65 + +VI NGS AGF+ + P+ + PS + R G+ ++ D A KR Sbjct: 6 QALVIDNGSGMCKAGFAGDDAPRAVFPS-IVGRPRHTGKDSYVG------DEAQSKRG-- 56 Query: 66 EVYTL--VDSQGLPYNWDALEMQWRYLYDTQLKVSPEELPLVITMPATNGKPDMAILERY 123 + TL G+ NWD +E W + + +L+V+PEE P+++T N K A E+ Sbjct: 57 -ILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPK---ANREKM 112 Query: 124 YELAFDKLNVPVFQIVIEPLAIALSMGKSSAFVIDIGASGCNVTPIIDGIVVKNAVVRSK 183 ++ F+ N P + I+ + + G+++ V+D G + PI +G + +A++R Sbjct: 113 TQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVSHTVPIYEGYALPHAILRLD 172 Query: 184 FGG-DFLDFQV 193 G D D+ + Sbjct: 173 LAGRDLTDYMM 183 Score = 38.9 bits (89), Expect = 0.005, Method: Compositional matrix adjust. Identities = 24/75 (32%), Positives = 41/75 (54%), Gaps = 5/75 (6%) Query: 388 LLTNVIITGSTSLIEGMEQRIIKELSIRFPQ-YKLTTFANQVMMDRKIQGWLGALTMANL 446 L NV+++G T++ G+ R+ KEL+ P K+ A +RK W+G +A+L Sbjct: 286 LYGNVVLSGGTTMFPGIADRMNKELTALAPSTMKIKIIAPP---ERKYSVWIGGSILASL 342 Query: 447 PSWSLGKWYSKEDYE 461 ++ W SKE+Y+ Sbjct: 343 STFQQ-MWISKEEYD 356 >5NW4-V nrPDB Length = 396 Score = 77.0 bits (188), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 47/185 (25%), Positives = 88/185 (47%), Gaps = 5/185 (2%) Query: 8 VVIHNGSHRTVAGFSNVELPQCIIPSSYIKRTDEGGEAEFIFGTYNMIDAAAEKRNGDEV 67 +V+ NGS AGF+ + P+ + PS + R G + + + A+ + G Sbjct: 29 LVVDNGSGMCKAGFAGDDAPRAVFPS-IVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILT 87 Query: 68 YTLVDSQGLPYNWDALEMQWRYLYDTQLKVSPEELPLVITMPATNGKPDMAILERYYELA 127 G+ NWD +E W + + +L+V+PEE P+++T N K A E+ ++ Sbjct: 88 LKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPK---ANREKMTQIM 144 Query: 128 FDKLNVPVFQIVIEPLAIALSMGKSSAFVIDIGASGCNVTPIIDGIVVKNAVVRSKFGG- 186 F+ N P + I+ + + G+++ V+D G + PI +G + +A++R G Sbjct: 145 FETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAILRLDLAGR 204 Query: 187 DFLDF 191 D D+ Sbjct: 205 DLTDY 209 Score = 35.0 bits (79), Expect = 0.070, Method: Compositional matrix adjust. Identities = 21/75 (28%), Positives = 40/75 (53%), Gaps = 5/75 (6%) Query: 388 LLTNVIITGSTSLIEGMEQRIIKELSIRFPQ-YKLTTFANQVMMDRKIQGWLGALTMANL 446 L N +++G T++ G+ R+ KE++ P K+ A +RK W+G +A+L Sbjct: 314 LYANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPP---ERKYSVWIGGSILASL 370 Query: 447 PSWSLGKWYSKEDYE 461 ++ W SK++Y+ Sbjct: 371 STFQ-QMWISKQEYD 384 >5MVV-A nrPDB Length = 378 Score = 76.3 bits (186), Expect = 3e-14, Method: Compositional matrix adjust. Identities = 49/195 (25%), Positives = 91/195 (46%), Gaps = 8/195 (4%) Query: 6 KCVVIHNGSHRTVAGFSNVELPQCIIPSSYIKRTDEGGEAEFIFGTYNMIDAAAEKRNGD 65 + +V+ NGS AG + + P+ + PS + R G + + A+ + G Sbjct: 9 QALVVDNGSGNVKAGVAGDDAPRSVFPS-IVGRPKNPGIMVGMEEKDAFVGDEAQTKRGI 67 Query: 66 EVYTLVDSQGLPYNWDALEMQWRYLYDTQLKVSPEELPLVITMPATNGKPDMAILERYYE 125 G+ NWD +E W + + +L+ +PEE P+++T N K + ER + Sbjct: 68 LTLKYPIEHGIVTNWDDMEKIWHHTFYNELRAAPEEHPVLLTEAPLNPKGNR---ERMTQ 124 Query: 126 LAFDKLNVPVFQIVIEPLAIALSMGKSSAFVIDIGASGCNVTPIIDGIVVKNAVVRSKFG 185 + F+ NVP + I+ + S G+++ V+D G + PI +G + +A++R Sbjct: 125 IMFESFNVPAMYVAIQAVLSLYSSGRTTGIVLDSGDGVSHTVPIYEGYALPHAIMRLDLA 184 Query: 186 G----DFLDFQVHER 196 G ++L +HER Sbjct: 185 GRDLTEYLMKILHER 199 Score = 37.0 bits (84), Expect = 0.018, Method: Compositional matrix adjust. Identities = 19/76 (25%), Positives = 45/76 (59%), Gaps = 7/76 (9%) Query: 388 LLTNVIITGSTSLIEGMEQRIIKELSIRFPQYKLTTFANQVMM--DRKIQGWLGALTMAN 445 L N++++G T++ EG+ +R+ ++++ P +T +V+ +RK W+G +++ Sbjct: 296 LYGNIVLSGGTTMYEGIGERLTRDITTLAP----STMKIKVVAPPERKYSVWIGGSILSS 351 Query: 446 LPSWSLGKWYSKEDYE 461 L ++ W +KE+Y+ Sbjct: 352 LSTFQQ-MWITKEEYD 366 >4CBX-A nrPDB Length = 378 Score = 76.3 bits (186), Expect = 3e-14, Method: Compositional matrix adjust. Identities = 47/188 (25%), Positives = 90/188 (47%), Gaps = 12/188 (6%) Query: 8 VVIHNGSHRTVAGFSNVELPQCIIPS----SYIKRTDEGGEAEFIFGTYNMIDAAAEKRN 63 +V+ NGS +G + + P+C+ PS + G E + + + A+ + Sbjct: 10 LVVDNGSGMVKSGLAGDDAPKCVFPSIIGIPKMPNIMVGMEQKECY-----VGDEAQNKR 64 Query: 64 GDEVYTLVDSQGLPYNWDALEMQWRYLYDTQLKVSPEELPLVITMPATNGKPDMAILERY 123 G G+ NWD +E WR+ + +L+VSPEE P+++T N K + E+ Sbjct: 65 GILTLKYPIEHGIVTNWDDMEKIWRHTFFNELRVSPEEHPVLLTEAPLNPKTNR---EKM 121 Query: 124 YELAFDKLNVPVFQIVIEPLAIALSMGKSSAFVIDIGASGCNVTPIIDGIVVKNAVVRSK 183 ++ F+ +VP + I+ + + G+++ V+D G + PI +G V+ +A+ R+ Sbjct: 122 TQIMFESFDVPAMYVSIQAILSLYASGRTTGIVLDSGDGVTHTVPIYEGYVLPHAINRTD 181 Query: 184 FGGDFLDF 191 G L + Sbjct: 182 MAGRDLTY 189 Score = 33.5 bits (75), Expect = 0.20, Method: Compositional matrix adjust. Identities = 19/75 (25%), Positives = 41/75 (54%), Gaps = 5/75 (6%) Query: 388 LLTNVIITGSTSLIEGMEQRIIKEL-SIRFPQYKLTTFANQVMMDRKIQGWLGALTMANL 446 L N++++G T++ + +R+ E+ S+ P K+ A +RK W+G +++L Sbjct: 296 LYNNIVLSGGTTMYNYIGERLTNEMTSLAPPSMKIKVIAPP---ERKYSVWIGGSILSSL 352 Query: 447 PSWSLGKWYSKEDYE 461 ++ W +KE+Y+ Sbjct: 353 STFQ-KMWITKEEYD 366 >3MN5-A nrPDB Length = 359 Score = 74.7 bits (182), Expect = 9e-14, Method: Compositional matrix adjust. Identities = 47/185 (25%), Positives = 84/185 (45%), Gaps = 21/185 (11%) Query: 8 VVIHNGSHRTVAGFSNVELPQCIIPSSYIKRTDEGGEAEFIFGTYNMIDAAAEKRNGDEV 67 +V NGS AGF+ + P+ + PS + DE A+ + G Sbjct: 8 LVCDNGSGLVKAGFAGDDAPRAVFPSIVGRVGDE-----------------AQSKRGILT 50 Query: 68 YTLVDSQGLPYNWDALEMQWRYLYDTQLKVSPEELPLVITMPATNGKPDMAILERYYELA 127 G+ NWD +E W + + +L+V+PEE P ++T N K + E+ ++ Sbjct: 51 LKYPIEHGIITNWDDMEKIWHHTFYNELRVAPEEHPTLLTEAPLNPKANR---EKMTQIM 107 Query: 128 FDKLNVPVFQIVIEPLAIALSMGKSSAFVIDIGASGCNVTPIIDGIVVKNAVVRSKFGG- 186 F+ NVP + I+ + + G+++ V+D G + PI +G + +A++R G Sbjct: 108 FETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGR 167 Query: 187 DFLDF 191 D D+ Sbjct: 168 DLTDY 172 Score = 32.3 bits (72), Expect = 0.44, Method: Compositional matrix adjust. Identities = 20/75 (26%), Positives = 40/75 (53%), Gaps = 5/75 (6%) Query: 388 LLTNVIITGSTSLIEGMEQRIIKELSIRFPQ-YKLTTFANQVMMDRKIQGWLGALTMANL 446 L N +++G T++ G+ R+ KE++ P K+ A +RK W+G +A+L Sbjct: 277 LYANNVMSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPP---ERKYSVWIGGSILASL 333 Query: 447 PSWSLGKWYSKEDYE 461 ++ W +K++Y+ Sbjct: 334 STFQ-QMWITKQEYD 347 >6F3A-A nrPDB Length = 376 Score = 67.0 bits (162), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 47/180 (26%), Positives = 83/180 (46%), Gaps = 5/180 (2%) Query: 8 VVIHNGSHRTVAGFSNVELPQCIIPSSYIKRTDEGGEAEFIFGTYNMIDAAAEKRNGDEV 67 VVI NGS AGF+ ++P+ P+ Y+ R I AE+ G Sbjct: 12 VVIDNGSGVIKAGFAGDQIPKYCFPN-YVGRPKHVRVMAGALEGDIFIGPKAEEHRGLLS 70 Query: 68 YTLVDSQGLPYNWDALEMQWRYLYDT-QLKVSPEELPLVITMPATNGKPDMAILERYYEL 126 G+ +W+ +E W+Y+Y QL+ EE P+++T N + + ER E+ Sbjct: 71 IRYPMEHGIVKDWNDMERIWQYVYSKDQLQTFSEEHPVLLTEAPLNPRKNR---ERAAEV 127 Query: 127 AFDKLNVPVFQIVIEPLAIALSMGKSSAFVIDIGASGCNVTPIIDGIVVKNAVVRSKFGG 186 F+ NVP I ++ + + G+++ V+D G + PI +G + ++++R G Sbjct: 128 FFETFNVPALFISMQAVLSLYATGRTTGVVLDSGDGVTHAVPIYEGFAMPHSIMRIDIAG 187 >3ULE-B nrPDB Length = 394 Score = 48.1 bits (113), Expect = 8e-06, Method: Compositional matrix adjust. Identities = 42/188 (22%), Positives = 80/188 (42%), Gaps = 11/188 (5%) Query: 4 NRKCVVIHNGSHRTVAGFSNVELPQCIIPS----SYIKRTDEGGEAEFIFGTYNMIDAAA 59 RK VV NG+ G++ P+ I P+ I+ T + G E + D A+ Sbjct: 5 GRKVVVCDNGTGFVKCGYAGSNFPEHIFPALVGRPIIRSTTKVGNIE--IKDLMVGDEAS 62 Query: 60 EKRNGDEVYTLVDSQGLPYNWDALEMQWRYLYDTQ-LKVSPEELPLVITMPATNGKPDMA 118 E R+ EV +++ G+ NWD ++ W Y + + L + +++T P N + Sbjct: 63 ELRSMLEVNYPMEN-GIVRNWDDMKHLWDYTFGPEKLNIDTRNCKILLTEPPMNPTKNR- 120 Query: 119 ILERYYELAFDKLNVPVFQIVIEPLAIALSMGKSSAFVIDIGASGCNVTPIIDGIVVKNA 178 E+ E+ F+ + I+ + + G + V+D G ++ P+ +G + + Sbjct: 121 --EKIVEVMFETYQFSGVYVAIQAVLTLYAQGLLTGVVVDSGDGVTHICPVYEGFSLPHL 178 Query: 179 VVRSKFGG 186 R G Sbjct: 179 TRRLDIAG 186 >5NW4-X nrPDB Length = 417 Score = 42.0 bits (97), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 52/197 (26%), Positives = 78/197 (39%), Gaps = 34/197 (17%) Query: 5 RKCVVIHNGSHRTVAGFSNVELPQCIIPSSYIKRTDEGGEAEFIFGTYNMIDAAAEKRNG 64 + VVI G T GF+ P+CIIPS IK+ G I N Sbjct: 13 KTAVVIDLGEAFTKCGFAGETGPRCIIPS-VIKKA----------GMPKPIKVVQYNINT 61 Query: 65 DEVYTLVDSQGLPYNWDALEMQWRYLYDTQLKVSPEELPLVIT----MPATNGKPDMAIL 120 +E+Y+ L+ LY L V+P + +V+ P+ + +L Sbjct: 62 EELYSY------------LKEFIHILYFRHLLVNPRDRRVVVIESVLCPSHFRETLTRVL 109 Query: 121 ERYYELAFDKLNVPVFQIVIEPLAIALSMGKSSAFVIDIGASGCNVTPIIDGIVVKNAVV 180 +Y+E VP + L L++G +SA V+D G V PI +GI V N Sbjct: 110 FKYFE-------VPSVLLAPSHLMALLTLGINSAMVLDCGYRESLVLPIYEGIPVLNCWG 162 Query: 181 RSKFGGDFLDFQVHERL 197 GG L ++ +L Sbjct: 163 ALPLGGKALHKELETQL 179 >6HTS-H nrPDB Length = 607 Score = 35.8 bits (81), Expect = 0.039, Method: Compositional matrix adjust. Identities = 22/87 (25%), Positives = 44/87 (50%), Gaps = 14/87 (16%) Query: 381 PEQVYSLLLTNVIITGSTSLIEGMEQRIIKELSIRFPQYKLTTFANQVMMDRKIQGWLGA 440 P+ + +L+ NV +TG ++ GM+ R+ KEL + ++ ++F Q+ + + W GA Sbjct: 480 PKDIQEMLVQNVFLTGGNTMYPGMKARMEKEL-LEMRPFR-SSFQVQLASNPVLDAWYGA 537 Query: 441 LTMANLPSWSLGK------WYSKEDYE 461 W+L W ++++YE Sbjct: 538 R------DWALNHLDDNEVWITRKEYE 558 >1K8K-A nrPDB Length = 418 Score = 35.4 bits (80), Expect = 0.052, Method: Compositional matrix adjust. Identities = 56/259 (21%), Positives = 99/259 (38%), Gaps = 45/259 (17%) Query: 8 VVIHNGSHRTVAGFSNVELPQCIIPSSY-IKRTDEGGEA------------EFIFGTYNM 54 V+ G+ T G++ PQ IIPS IK + + G+ +F G Sbjct: 8 CVVDCGTGYTKLGYAGNTEPQFIIPSCIAIKESAKVGDQAQRRVMKGVDDLDFFIG---- 63 Query: 55 IDAAAEKRNGDEVYTLVDSQGLPYNWDALEMQWRYLYDTQLKVSPEELPLVITMPATNGK 114 D A EK + + G+ +WD +E + L+ PE+ ++T P N Sbjct: 64 -DEAIEKPTYATKWPI--RHGIVEDWDLMERFMEQVIFKYLRAEPEDHYFLLTEPPLNTP 120 Query: 115 PDMAILERYYELAFDKLNVPVFQIVIEPLAIALSMGKS--------SAFVIDIGASGCNV 166 + E E+ F+ NVP I ++ + + S + VID G +V Sbjct: 121 ENR---EYTAEIMFESFNVPGLYIAVQAVLALAASWTSRQVGERTLTGTVIDSGDGVTHV 177 Query: 167 TPIIDGIVVKNAVVRSKFGGDFLDFQVHERLAPL---IKEENDMENMADEQKRSTDVW-- 221 P+ +G V+ + + G + + + + L I E +E ++R + V Sbjct: 178 IPVAEGYVIGSCIKHIPIAGRDITYFIQQLLRDREVGIPPEQSLETAKAVKERYSYVCPD 237 Query: 222 ---------YEASTWIQQF 231 + S WI+Q+ Sbjct: 238 LVKEFNKYDTDGSKWIKQY 256 >4AM6-A nrPDB Length = 655 Score = 33.1 bits (74), Expect = 0.29, Method: Compositional matrix adjust. Identities = 18/69 (26%), Positives = 35/69 (50%), Gaps = 1/69 (1%) Query: 120 LERYYELAFDKLNVPVFQIVIEPLAIALSMGKS-SAFVIDIGASGCNVTPIIDGIVVKNA 178 +E + + +L I+ E LA G S S V++IGA+ + + +G V++++ Sbjct: 237 VETFIRVLLTELQFQAVAIIQESLATCYGAGISTSTCVVNIGAAETRIACVDEGTVLEHS 296 Query: 179 VVRSKFGGD 187 + +GGD Sbjct: 297 AITLDYGGD 305 >3DWL-A nrPDB Length = 427 Score = 31.6 bits (70), Expect = 0.83, Method: Compositional matrix adjust. Identities = 51/255 (20%), Positives = 91/255 (35%), Gaps = 31/255 (12%) Query: 79 NWDALEMQWRYLYDTQLKVSPEELPLVITMPATNGKPDMAILERYYELAFDKLNVPVFQI 138 NWD +E W+ L+ PE+ ++T P N + E E+ F+ N I Sbjct: 101 NWDHMERFWQQSLFKYLRCEPEDHYFLLTEPPLNPPENR---ENTAEIMFESFNCAGLYI 157 Query: 139 VIEPLAIALSMGKSS--------AFVIDIGASGCNVTPIIDGIVVKNAVVRSKFGGDFLD 190 ++ + + SS V+D G ++ P+ +G V+ +++ G + Sbjct: 158 AVQAVLALAASWTSSKVTDRSLTGTVVDSGDGVTHIIPVAEGYVIGSSIKTMPLAGRDVT 217 Query: 191 FQVHERL------------APLIKEEN-----DMENMADEQKRSTDVWYEASTWIQQFKS 233 + V L A IKEE D+ R D + + ++ S Sbjct: 218 YFVQSLLRDRNEPDSSLKTAERIKEECCYVCPDIVKEFSRFDREPDRYLKYASESITGHS 277 Query: 234 TMLQVSEKDLFELERYYKEQ---ADIYAKQQEQLKQMDQQLQYTALTGSPNNPLVQKKNF 290 T + V + E ++ + +D E + + Q G N ++ + Sbjct: 278 TTIDVGFERFLAPEIFFNPEIASSDFLTPLPELVDNVVQSSPIDVRKGLYKNIVLSGGST 337 Query: 291 LFKPLNKTLTLDLKE 305 LFK L DLK Sbjct: 338 LFKNFGNRLQRDLKR 352 >3FIJ-A nrPDB Length = 254 Score = 30.8 bits (68), Expect = 1.3, Method: Compositional matrix adjust. Identities = 19/64 (29%), Positives = 33/64 (51%), Gaps = 12/64 (18%) Query: 400 LIEGMEQRIIKELSIRFPQYKLTTFANQVMMDRKIQGWLGALTMANLPSWSLG-KWYSKE 458 L+ + + IK+L+ P +K+T R G + A+ NLPSW LG +W+ + Sbjct: 173 LVNSLHHQFIKKLA---PSFKVTA--------RTADGMIEAVEGDNLPSWYLGVQWHPEL 221 Query: 459 DYET 462 ++T Sbjct: 222 MFQT 225 >4AMG-A nrPDB Length = 400 Score = 30.8 bits (68), Expect = 1.4, Method: Compositional matrix adjust. Identities = 18/68 (26%), Positives = 30/68 (44%), Gaps = 4/68 (5%) Query: 9 VIHNGSHRTVAGFSNVELPQCIIPSSYIKRTDEGGEAEFIFGTYNMIDAAAEKRNGDEVY 68 +IH+G T+ +PQC+IP + T+ + + G DA A ++ Sbjct: 308 IIHHGGSGTLLTALAAGVPQCVIPHGSYQDTNR----DVLTGLGIGFDAEAGSLGAEQCR 363 Query: 69 TLVDSQGL 76 L+D GL Sbjct: 364 RLLDDAGL 371 >4JUK-A nrPDB Length = 329 Score = 30.4 bits (67), Expect = 1.7, Method: Compositional matrix adjust. Identities = 22/87 (25%), Positives = 38/87 (43%), Gaps = 13/87 (14%) Query: 368 GDNNSTASSSNISPEQVYSLLLTNVIITGSTSLIEGMEQRIIKELSIRFPQYKLTTFANQ 427 GD+ +N S EQV +++ NV +T + ++E + +L+ P Sbjct: 6 GDHICIGYHANNSTEQVDTIMEKNVTVTHAQDILEKTHNGKLCDLNGVKP---------L 56 Query: 428 VMMDRKIQGWLGALTMA----NLPSWS 450 ++ D + GWL M N+P WS Sbjct: 57 ILKDCSVAGWLLGNPMCDEFINVPEWS 83 >4AV2-A nrPDB Length = 745 Score = 30.0 bits (66), Expect = 2.2, Method: Compositional matrix adjust. Identities = 19/62 (30%), Positives = 34/62 (54%), Gaps = 4/62 (6%) Query: 105 VITMPATNG---KPDMAILERYYELAFDKLNVPVFQIVIEPLAIALSMGKSSAFVIDIGA 161 V+ PATN +++E++ +L D+L+VP Q++IE + + G S + GA Sbjct: 457 VLIDPATNTLIVTDTRSVIEKFRKL-IDELDVPAQQVMIEARIVEAADGFSRDLGVKFGA 515 Query: 162 SG 163 +G Sbjct: 516 TG 517 >4MHI-A nrPDB Length = 334 Score = 29.6 bits (65), Expect = 2.6, Method: Compositional matrix adjust. Identities = 22/87 (25%), Positives = 37/87 (42%), Gaps = 13/87 (14%) Query: 368 GDNNSTASSSNISPEQVYSLLLTNVIITGSTSLIEGMEQRIIKELSIRFPQYKLTTFANQ 427 GD +N S EQV +++ NV +T + ++E + +L+ P Sbjct: 4 GDQICIGYHANNSTEQVDTIMEKNVTVTHAQDILEKTHNGKLCDLNGVKP---------L 54 Query: 428 VMMDRKIQGWLGALTMA----NLPSWS 450 ++ D + GWL M N+P WS Sbjct: 55 ILRDCSVAGWLLGNPMCDEFINVPEWS 81 >3K9V-A nrPDB Length = 482 Score = 29.3 bits (64), Expect = 3.8, Method: Compositional matrix adjust. Identities = 20/66 (30%), Positives = 37/66 (56%), Gaps = 5/66 (7%) Query: 189 LDFQVHERLAPLIKEENDMENMADEQKRSTDVWYEASTWIQQFKSTMLQVSEKDLFELER 248 LD +++E LA ++ M+ + DE+ R D++ E + W F+S L + EK L++ Sbjct: 143 LDKKINEVLADFLER---MDELCDERGRIPDLYSELNKW--SFESICLVLYEKRFGLLQK 197 Query: 249 YYKEQA 254 +E+A Sbjct: 198 ETEEEA 203 >5LY3-A nrPDB Length = 432 Score = 29.3 bits (64), Expect = 4.2, Method: Compositional matrix adjust. Identities = 28/112 (25%), Positives = 51/112 (45%), Gaps = 6/112 (5%) Query: 80 WDALEMQWRYLYDTQLKVS-PEELPLVITMPATNGKPDM---AILERYYELAFDKLNVPV 135 W L+ RY Q VS PE ++ + + PD AI + Y ELA + + Sbjct: 101 WRVLKELARYTL-AQFPVSDPEFAGWLVAVALSALAPDYMYKAIFDIYDELA-SEFKIYA 158 Query: 136 FQIVIEPLAIALSMGKSSAFVIDIGASGCNVTPIIDGIVVKNAVVRSKFGGD 187 I+ +PLA+A++ + +++ G V PI ++ + V ++ G + Sbjct: 159 VTILPQPLAVAIAENAVNCVIVEGGHGNIQVAPISFALIREGLVALNRGGAE 210 >3K85-A nrPDB Length = 357 Score = 29.3 bits (64), Expect = 4.2, Method: Compositional matrix adjust. Identities = 13/38 (34%), Positives = 24/38 (63%) Query: 387 LLLTNVIITGSTSLIEGMEQRIIKELSIRFPQYKLTTF 424 L ++ + I G SLI+G+ RII++ + +K+TT+ Sbjct: 67 LSMSQLEIDGEASLIKGVYNRIIRDYRLEPKSFKITTY 104 >4I6M-B nrPDB Length = 439 Score = 28.9 bits (63), Expect = 5.1, Method: Compositional matrix adjust. Identities = 42/197 (21%), Positives = 78/197 (39%), Gaps = 33/197 (16%) Query: 8 VVIHNGSHRTVAGFSNVE----LPQCIIPSSYIKRTDEGG-----------EAEFIFGTY 52 ++I+ S T+ F E +P+ IP+ + T + G +AE I Sbjct: 10 LIIYPRSQTTLVQFGLNEETFTVPELEIPTQIYRTTRQDGSYTYHSTNKDNKAELIKPIQ 69 Query: 53 N--MIDAAAEKRNGDEVYTLVDSQGLPYNWDALEMQWRYLYDTQLKVSPEELPLVITMPA 110 N +ID +A + ++ + S N DA E + +PL++ Sbjct: 70 NGEIIDISAFTQFLRLIFVSILSDRANKNQDAFEAEL------------SNIPLLLITHH 117 Query: 111 TNGKPDMAILERYYELAFDKLNVPVFQIVIEPLAIALSM-GKSSAFVIDIGASGCNVTPI 169 + + D+ I+ +Y F+ L + + LA SM + +ID+G ++ PI Sbjct: 118 SWSQSDLEIITQY---VFESLEINNLIQLPASLAATYSMISLQNCCIIDVGTHHTDIIPI 174 Query: 170 IDGIVVKNAVVRSKFGG 186 +D + + V GG Sbjct: 175 VDYAQLDHLVSSIPMGG 191 >3WEE-A nrPDB Length = 476 Score = 28.5 bits (62), Expect = 5.8, Method: Compositional matrix adjust. Identities = 42/197 (21%), Positives = 78/197 (39%), Gaps = 33/197 (16%) Query: 8 VVIHNGSHRTVAGFSNVE----LPQCIIPSSYIKRTDEGG-----------EAEFIFGTY 52 ++I+ S T+ F E +P+ IP+ + T + G +AE I Sbjct: 19 LIIYPRSQTTLVQFGLNEETFTVPELEIPTQIYRTTRQDGSYTYHSTNKDNKAELIKPIQ 78 Query: 53 N--MIDAAAEKRNGDEVYTLVDSQGLPYNWDALEMQWRYLYDTQLKVSPEELPLVITMPA 110 N +ID +A + ++ + S N DA E + +PL++ Sbjct: 79 NGEIIDISAFTQFLRLIFVSILSDRANKNQDAFEAEL------------SNIPLLLITHH 126 Query: 111 TNGKPDMAILERYYELAFDKLNVPVFQIVIEPLAIALSM-GKSSAFVIDIGASGCNVTPI 169 + + D+ I+ +Y F+ L + + LA SM + +ID+G ++ PI Sbjct: 127 SWSQSDLEIITQY---VFESLEINNLIQLPASLAATYSMISLQNCCIIDVGTHHTDIIPI 183 Query: 170 IDGIVVKNAVVRSKFGG 186 +D + + V GG Sbjct: 184 VDYAQLDHLVSSIPMGG 200 >6GEJ-R nrPDB Length = 438 Score = 28.5 bits (62), Expect = 6.7, Method: Compositional matrix adjust. Identities = 24/97 (24%), Positives = 39/97 (40%), Gaps = 1/97 (1%) Query: 365 TNVGDNNSTASSSNISPEQVYSLLLTNVIITGSTSLIEGMEQRIIKELSIRFPQYKLTTF 424 T G + S ++ PE V L++ N++ TG + QR+ EL + P T Sbjct: 326 TKPGIVEAILESLSMLPEIVRPLMVGNIVCTGGNFNLPNFAQRLAAELQRQLPT-DWTCH 384 Query: 425 ANQVMMDRKIQGWLGALTMANLPSWSLGKWYSKEDYE 461 + D + GW A S+ + +E YE Sbjct: 385 VSVPEGDCALFGWEVMSQFAKTDSYRKARVTREEYYE 421 >5V7X-A nrPDB Length = 752 Score = 28.5 bits (62), Expect = 7.1, Method: Compositional matrix adjust. Identities = 17/53 (32%), Positives = 30/53 (56%), Gaps = 1/53 (1%) Query: 379 ISPEQVYSLLLTNVIITGSTSLIEGM-EQRIIKELSIRFPQYKLTTFANQVMM 430 ++ ++V S LL N+I G T L+E + E+ I L RF ++ T+ V++ Sbjct: 1 MAKKEVKSSLLDNMIGVGDTVLLEPLNEETFIDNLKKRFDHNEIYTYIGSVVI 53 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 4I6M-A nrPDB 708 0.0 3QB0-A nrPDB 522 e-148 5NBL-C nrPDB 333 1e-91 3MN5-A nrPDB 314 8e-86 4PL7-A nrPDB 283 1e-76 5NW4-V nrPDB 283 1e-76 5MVV-A nrPDB 275 2e-74 1C0F-A nrPDB 273 1e-73 4CBX-A nrPDB 266 1e-71 6F3A-A nrPDB 244 6e-65 3ULE-B nrPDB 230 1e-60 5NW4-X nrPDB 178 4e-45 Sequences not found previously or not previously below threshold: 3DWL-A nrPDB 160 1e-39 1K8K-A nrPDB 148 8e-36 6GEJ-R nrPDB 70 2e-12 6HTS-H nrPDB 70 2e-12 4AM6-A nrPDB 64 1e-10 4FO0-A nrPDB 47 2e-05 5LY3-A nrPDB 46 4e-05 4I6M-B nrPDB 45 7e-05 3WEE-A nrPDB 45 8e-05 3H1Q-A nrPDB 31 1.2 6FHI-C nrPDB 31 1.7 5WUA-A nrPDB 30 2.7 2O1M-A nrPDB 28 8.3 >4I6M-A nrPDB Length = 477 Score = 708 bits (1826), Expect = 0.0, Method: Composition-based stats. Identities = 477/477 (100%), Positives = 477/477 (100%) Query: 1 MTLNRKCVVIHNGSHRTVAGFSNVELPQCIIPSSYIKRTDEGGEAEFIFGTYNMIDAAAE 60 MTLNRKCVVIHNGSHRTVAGFSNVELPQCIIPSSYIKRTDEGGEAEFIFGTYNMIDAAAE Sbjct: 1 MTLNRKCVVIHNGSHRTVAGFSNVELPQCIIPSSYIKRTDEGGEAEFIFGTYNMIDAAAE 60 Query: 61 KRNGDEVYTLVDSQGLPYNWDALEMQWRYLYDTQLKVSPEELPLVITMPATNGKPDMAIL 120 KRNGDEVYTLVDSQGLPYNWDALEMQWRYLYDTQLKVSPEELPLVITMPATNGKPDMAIL Sbjct: 61 KRNGDEVYTLVDSQGLPYNWDALEMQWRYLYDTQLKVSPEELPLVITMPATNGKPDMAIL 120 Query: 121 ERYYELAFDKLNVPVFQIVIEPLAIALSMGKSSAFVIDIGASGCNVTPIIDGIVVKNAVV 180 ERYYELAFDKLNVPVFQIVIEPLAIALSMGKSSAFVIDIGASGCNVTPIIDGIVVKNAVV Sbjct: 121 ERYYELAFDKLNVPVFQIVIEPLAIALSMGKSSAFVIDIGASGCNVTPIIDGIVVKNAVV 180 Query: 181 RSKFGGDFLDFQVHERLAPLIKEENDMENMADEQKRSTDVWYEASTWIQQFKSTMLQVSE 240 RSKFGGDFLDFQVHERLAPLIKEENDMENMADEQKRSTDVWYEASTWIQQFKSTMLQVSE Sbjct: 181 RSKFGGDFLDFQVHERLAPLIKEENDMENMADEQKRSTDVWYEASTWIQQFKSTMLQVSE 240 Query: 241 KDLFELERYYKEQADIYAKQQEQLKQMDQQLQYTALTGSPNNPLVQKKNFLFKPLNKTLT 300 KDLFELERYYKEQADIYAKQQEQLKQMDQQLQYTALTGSPNNPLVQKKNFLFKPLNKTLT Sbjct: 241 KDLFELERYYKEQADIYAKQQEQLKQMDQQLQYTALTGSPNNPLVQKKNFLFKPLNKTLT 300 Query: 301 LDLKECYQFAEYLFKPQLISDKFSPEDGLGPLMAKSVKKAGASINSMKANTSTNPNGLGT 360 LDLKECYQFAEYLFKPQLISDKFSPEDGLGPLMAKSVKKAGASINSMKANTSTNPNGLGT Sbjct: 301 LDLKECYQFAEYLFKPQLISDKFSPEDGLGPLMAKSVKKAGASINSMKANTSTNPNGLGT 360 Query: 361 SHINTNVGDNNSTASSSNISPEQVYSLLLTNVIITGSTSLIEGMEQRIIKELSIRFPQYK 420 SHINTNVGDNNSTASSSNISPEQVYSLLLTNVIITGSTSLIEGMEQRIIKELSIRFPQYK Sbjct: 361 SHINTNVGDNNSTASSSNISPEQVYSLLLTNVIITGSTSLIEGMEQRIIKELSIRFPQYK 420 Query: 421 LTTFANQVMMDRKIQGWLGALTMANLPSWSLGKWYSKEDYETLKRDRKQSQATNATN 477 LTTFANQVMMDRKIQGWLGALTMANLPSWSLGKWYSKEDYETLKRDRKQSQATNATN Sbjct: 421 LTTFANQVMMDRKIQGWLGALTMANLPSWSLGKWYSKEDYETLKRDRKQSQATNATN 477 >3QB0-A nrPDB Length = 498 Score = 522 bits (1345), Expect = e-148, Method: Composition-based stats. Identities = 116/506 (22%), Positives = 212/506 (41%), Gaps = 82/506 (16%) Query: 6 KCVVIHNGSHRTVAGFSNVELPQCIIPSSYIKRT-DEGGEAEFIFGTYNMIDAAAEKRNG 64 VVI GS+ T G+S + PQ I+PS Y K T DEG + F + + R Sbjct: 24 SAVVIDPGSYTTNIGYSGSDFPQSILPSVYGKYTADEGNKKIFSEQSIGI------PRKD 77 Query: 65 DEVYTLVDSQGLPYNWDALEMQWRYLYDTQLKV-SPEELPLVITMPATNGKPDMAILERY 123 E+ ++++ GL +WD + QW++ +L + S +P ++T P N + ++ Sbjct: 78 YELKPIIEN-GLVIDWDTAQEQWQWALQNELYLNSNSGIPALLTEPVWNSTENR---KKS 133 Query: 124 YELAFDKLNVPVFQIVIEPLAIALSMGKSSAFVIDIGASGCNVTPIIDGIVVKNAVVRSK 183 E+ + + + ++ + G+ + V+DIG C+V+PI+DG+ + + R+ Sbjct: 134 LEVLLEGMQFEACYLAPTSTCVSFAAGRPNCLVVDIGHDTCSVSPIVDGMTLSKSTRRNF 193 Query: 184 FGGDFLDFQVHERLAPLIKEENDMENMADEQKRSTDVWYEASTWIQQFKSTMLQVSEKDL 243 G F++ + + L P + + A +Q++ + K T +K L Sbjct: 194 IAGKFINHLIKKALEP----KEIIPLFAIKQRKP-----------EFIKKTFDYEVDKSL 238 Query: 244 FELER---YYKEQAD--IYAKQQEQLKQMDQQLQYTALTGSPNNPLVQKKNFLFKPLNKT 298 ++ +++E + + + L++ +L TA K + P N+ Sbjct: 239 YDYANNRGFFQECKETLCHICPTKTLEETKTELSSTA------------KRSIESPWNEE 286 Query: 299 LTLDLKECYQFAEYLFKPQ-----------------LISDKFSPEDGLGPL-MAKSVKK- 339 + D + Y FAE LF P+ + + P P + KS KK Sbjct: 287 IVFDNETRYGFAEELFLPKEDDIPANWPRSNSGVVKTWRNDYVPLKRTKPSGVNKSDKKV 346 Query: 340 ---------AGASINSMKANTSTNPNGLGTSHI---------NTNVGDNNSTASSSNISP 381 A + S AN++ PN G + N +G + SS S Sbjct: 347 TPTEEKEQEAVSKSTSPAANSADTPNETGKRPLEEEKPPKENNELIGLADLVYSSIMSSD 406 Query: 382 EQVYSLLLTNVIITGSTSLIEGMEQRIIKELSIRFPQYKLTTFANQVMMDRKIQGWLGAL 441 + + L NV++TG TS I G+ R++ EL+ P K ++R+ Q WLG Sbjct: 407 VDLRATLAHNVVLTGGTSSIPGLSDRLMTELNKILPSLKFRILTTGHTIERQYQSWLGGS 466 Query: 442 TMANLPSWSLGKWYSKEDYETLKRDR 467 + +L ++ W K++YE + +R Sbjct: 467 ILTSLGTFH-QLWVGKKEYEEVGVER 491 >5NBL-C nrPDB Length = 375 Score = 333 bits (853), Expect = 1e-91, Method: Composition-based stats. Identities = 92/460 (20%), Positives = 173/460 (37%), Gaps = 102/460 (22%) Query: 7 CVVIHNGSHRTVAGFSNVELPQCIIPSSYIKRTDEGGEAEFIFGTYNMIDAAAEKRNGDE 66 +VI NGS AGF+ + P+ + PS + R G + + + A+ + G Sbjct: 7 ALVIDNGSGMCKAGFAGDDAPRAVFPS-IVGRPRHQGIMVGMGQKDSYVGDEAQSKRGIL 65 Query: 67 VYTLVDSQGLPYNWDALEMQWRYLYDTQLKVSPEELPLVITMPATNGKPDMAILERYYEL 126 G+ NWD +E W + + +L+V+PEE P+++T N K + E+ ++ Sbjct: 66 TLRYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPMNPKSNR---EKMTQI 122 Query: 127 AFDKLNVPVFQIVIEPLAIALSMGKSSAFVIDIGASGCNVTPIIDGIVVKNAVVRSKFGG 186 F+ NVP F + I+ + S G+++ V+D G +V PI G + +A++R G Sbjct: 123 MFETFNVPAFYVSIQAVLSLYSSGRTTGIVLDSGDGVTHVVPIYAGFSLPHAILRIDLAG 182 Query: 187 -DFLDFQVHERLAPLIKEENDMENMADEQKRSTDVWYEASTWIQQFKSTMLQVSEKDLFE 245 D D+ + S F +T + +D+ E Sbjct: 183 RDLTDYLMK----------------------------ILSERGYSFSTTAEREIVRDIKE 214 Query: 246 LERYYKEQADIYAKQQEQLKQMDQQLQYTALTGSPNNPLVQKKNFLFKPLNKTLTLDLKE 305 Y +Q++Q A + S + P + +T+ + Sbjct: 215 --------KLCYVAL-----DFEQEMQTAAQSSS-------IEKSYELPDGQVITIGNE- 253 Query: 306 CYQFAEYLFKPQLISDKFSPEDGLGPLMAKSVKKAGASINSMKANTSTNPNGLGTSHINT 365 ++ E LF P ++ + + D Sbjct: 254 RFRAPEALFHPSVLGLESAGIDQT------------------------------------ 277 Query: 366 NVGDNNSTASSSNISPEQVYSLLLTNVIITGSTSLIEGMEQRIIKELSIRFP-QYKLTTF 424 T +S V L N++++G T++ G+ +R+ KE++ P K+ Sbjct: 278 -------TYNSIMKCDVDVRKELYGNIVMSGGTTMFPGIAERMQKEITALAPSSMKVKII 330 Query: 425 ANQVMMDRKIQGWLGALTMANLPSWSLGKWYSKEDYETLK 464 A +RK W+G +A+L ++ W SK++Y+ Sbjct: 331 APP---ERKYSVWIGGSILASLTTFQ-QMWISKQEYDESG 366 >3MN5-A nrPDB Length = 359 Score = 314 bits (803), Expect = 8e-86, Method: Composition-based stats. Identities = 81/461 (17%), Positives = 164/461 (35%), Gaps = 118/461 (25%) Query: 6 KCVVIHNGSHRTVAGFSNVELPQCIIPSSYIKRTDEGGEAEFIFGTYNMIDAAAEKRNGD 65 +V NGS AGF+ + P+ + PS + + A+ + G Sbjct: 6 TALVCDNGSGLVKAGFAGDDAPRAVFPSIVGR-----------------VGDEAQSKRGI 48 Query: 66 EVYTLVDSQGLPYNWDALEMQWRYLYDTQLKVSPEELPLVITMPATNGKPDMAILERYYE 125 G+ NWD +E W + + +L+V+PEE P ++T N K + E+ + Sbjct: 49 LTLKYPIEHGIITNWDDMEKIWHHTFYNELRVAPEEHPTLLTEAPLNPKANR---EKMTQ 105 Query: 126 LAFDKLNVPVFQIVIEPLAIALSMGKSSAFVIDIGASGCNVTPIIDGIVVKNAVVRSKFG 185 + F+ NVP + I+ + + G+++ V+D G + PI +G + +A++R Sbjct: 106 IMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLA 165 Query: 186 G-DFLDFQVHERLAPLIKEENDMENMADEQKRSTDVWYEASTWIQQFKSTMLQVSEKDLF 244 G D D+ + ++ + V ++ K + V+ Sbjct: 166 GRDLTDYLMK----------------ILTERGYSFVTTAEREIVRDIKEKLCYVA----L 205 Query: 245 ELERYYKEQADIYAKQQEQLKQMDQQLQYTALTGSPNNPLVQKKNFLFKPLNKTLTLDLK 304 + E +M ++L + P + +T+ + Sbjct: 206 DFEN-----------------EMATAASSSSL-----------EKSYELPDGQVITIGNE 237 Query: 305 ECYQFAEYLFKPQLISDKFSPEDGLGPLMAKSVKKAGASINSMKANTSTNPNGLGTSHIN 364 ++ E LF+P I Sbjct: 238 -RFRCPETLFQPSFIG-------------------------------------------M 253 Query: 365 TNVGDNNSTASSSNISPEQVYSLLLTNVIITGSTSLIEGMEQRIIKELSIRFPQ-YKLTT 423 + G + +T +S + L N +++G T++ G+ R+ KE++ P K+ Sbjct: 254 ESAGIHETTYNSIMKCDIDIRKDLYANNVMSGGTTMYPGIADRMQKEITALAPSTMKIKI 313 Query: 424 FANQVMMDRKIQGWLGALTMANLPSWSLGKWYSKEDYETLK 464 A +RK W+G +A+L ++ W +K++Y+ Sbjct: 314 IAPP---ERKYSVWIGGSILASLSTFQ-QMWITKQEYDEAG 350 >4PL7-A nrPDB Length = 440 Score = 283 bits (724), Expect = 1e-76, Method: Composition-based stats. Identities = 84/463 (18%), Positives = 160/463 (34%), Gaps = 108/463 (23%) Query: 7 CVVIHNGSHRTVAGFSNVELPQCIIPSSYIKRTDEGGEAEFIFGTYNMIDAAAEKRNGDE 66 +VI NGS AG++ + P + PS + R G + + + A+ + G Sbjct: 7 ALVIDNGSGMCKAGYAGDDAPHTVFPS-VVGRPRHQGVMVGMGQKDSFVGDEAQSKRGIL 65 Query: 67 VYTLVDSQGLPYNWDALEMQWRYLYDTQLKVSPEELPLVITMPATNGKPDMAILERYYEL 126 G+ NWD +E W + + +L+++PEE P+++T N K + E+ ++ Sbjct: 66 TLRYPIEHGIVTNWDDMEKIWHHTFYNELRLAPEEHPVLLTEAPMNPKSNR---EKMTQI 122 Query: 127 AFDKLNVPVFQIVIEPLAIALSMGKSSAFVIDIGASGCNVTPIIDGIVVKNAVVRSKFGG 186 F+ NVP F + I+ + + G+++ V+D G +V PI G + +A++R G Sbjct: 123 MFETFNVPAFYVSIQAVLSLYASGRTTGIVLDSGDGVTHVVPIYAGFSLPHAILRIDLAG 182 Query: 187 -DFLDFQVHERLAPLIKEENDMENMADEQKRSTDVWYEASTWIQQFKSTMLQVSEKDLFE 245 D D+ + S F ++ + +D+ E Sbjct: 183 RDLTDYLMK----------------------------ILSERGYTFSTSAEREIVRDIKE 214 Query: 246 LERYYKEQADIYAKQQEQLKQMDQQLQYTALTGSPNNPLVQKKNFLFKPLNKTLTLDLKE 305 Y DQ+LQ ++ + P + +T+ + Sbjct: 215 --------KLCYVAL-----DFDQELQT-------SSQSSSIEKSYELPDGQVITIGNE- 253 Query: 306 CYQFAEYLFKPQLISDKFSPEDGLG-PLMAKSV---KKAGASINSMKANTSTNPNGLGTS 361 ++ E LF P ++ + S D + K +K S M T+ P G+ Sbjct: 254 RFRAPEALFHPSVLGLEASGIDQTTYNSIMKCDVDVRKELYSNIVMSGGTTMFP-GIAER 312 Query: 362 HINTNVGDNNSTASSSNISPEQVYSLLLTNVIITGSTSLIEGMEQRIIKELSIRFPQYKL 421 S+ +P P+ K Sbjct: 313 MQKELTALAPSSMKVKISAP-----------------------------------PERKY 337 Query: 422 TTFANQVMMDRKIQGWLGALTMANLPSWSLGKWYSKEDYETLK 464 + W+G +A+L ++ W SK++Y+ Sbjct: 338 SV-------------WIGGSILASLGTFQ-QMWISKQEYDESG 366 >5NW4-V nrPDB Length = 396 Score = 283 bits (723), Expect = 1e-76, Method: Composition-based stats. Identities = 46/189 (24%), Positives = 89/189 (47%), Gaps = 5/189 (2%) Query: 7 CVVIHNGSHRTVAGFSNVELPQCIIPSSYIKRTDEGGEAEFIFGTYNMIDAAAEKRNGDE 66 +V+ NGS AGF+ + P+ + PS + R G + + + A+ + G Sbjct: 28 ALVVDNGSGMCKAGFAGDDAPRAVFPS-IVGRPRHQGVMVGMGQKDSYVGDEAQSKRGIL 86 Query: 67 VYTLVDSQGLPYNWDALEMQWRYLYDTQLKVSPEELPLVITMPATNGKPDMAILERYYEL 126 G+ NWD +E W + + +L+V+PEE P+++T N K + E+ ++ Sbjct: 87 TLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANR---EKMTQI 143 Query: 127 AFDKLNVPVFQIVIEPLAIALSMGKSSAFVIDIGASGCNVTPIIDGIVVKNAVVRSKFGG 186 F+ N P + I+ + + G+++ V+D G + PI +G + +A++R G Sbjct: 144 MFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAILRLDLAG 203 Query: 187 -DFLDFQVH 194 D D+ + Sbjct: 204 RDLTDYLMK 212 Score = 83.3 bits (204), Expect = 2e-16, Method: Composition-based stats. Identities = 24/101 (23%), Positives = 48/101 (47%), Gaps = 5/101 (4%) Query: 365 TNVGDNNSTASSSNISPEQVYSLLLTNVIITGSTSLIEGMEQRIIKELSIRFPQ-YKLTT 423 + G + +T +S + L N +++G T++ G+ R+ KE++ P K+ Sbjct: 291 ESCGIHETTFNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKI 350 Query: 424 FANQVMMDRKIQGWLGALTMANLPSWSLGKWYSKEDYETLK 464 A +RK W+G +A+L ++ W SK++Y+ Sbjct: 351 IAPP---ERKYSVWIGGSILASLSTFQ-QMWISKQEYDESG 387 >5MVV-A nrPDB Length = 378 Score = 275 bits (704), Expect = 2e-74, Method: Composition-based stats. Identities = 49/195 (25%), Positives = 91/195 (46%), Gaps = 8/195 (4%) Query: 6 KCVVIHNGSHRTVAGFSNVELPQCIIPSSYIKRTDEGGEAEFIFGTYNMIDAAAEKRNGD 65 + +V+ NGS AG + + P+ + PS + R G + + A+ + G Sbjct: 9 QALVVDNGSGNVKAGVAGDDAPRSVFPS-IVGRPKNPGIMVGMEEKDAFVGDEAQTKRGI 67 Query: 66 EVYTLVDSQGLPYNWDALEMQWRYLYDTQLKVSPEELPLVITMPATNGKPDMAILERYYE 125 G+ NWD +E W + + +L+ +PEE P+++T N K + ER + Sbjct: 68 LTLKYPIEHGIVTNWDDMEKIWHHTFYNELRAAPEEHPVLLTEAPLNPKGNR---ERMTQ 124 Query: 126 LAFDKLNVPVFQIVIEPLAIALSMGKSSAFVIDIGASGCNVTPIIDGIVVKNAVVRSKFG 185 + F+ NVP + I+ + S G+++ V+D G + PI +G + +A++R Sbjct: 125 IMFESFNVPAMYVAIQAVLSLYSSGRTTGIVLDSGDGVSHTVPIYEGYALPHAIMRLDLA 184 Query: 186 G----DFLDFQVHER 196 G ++L +HER Sbjct: 185 GRDLTEYLMKILHER 199 Score = 76.0 bits (185), Expect = 3e-14, Method: Composition-based stats. Identities = 25/111 (22%), Positives = 54/111 (48%), Gaps = 9/111 (8%) Query: 355 PNGLGTSHINTNVGDNNSTASSSNISPEQVYSLLLTNVIITGSTSLIEGMEQRIIKELSI 414 P+ LG G + +T +S + L N++++G T++ EG+ +R+ ++++ Sbjct: 267 PSFLGK----EAAGIHTTTFNSIKKCDVDIRKDLYGNIVLSGGTTMYEGIGERLTRDITT 322 Query: 415 RFPQ-YKLTTFANQVMMDRKIQGWLGALTMANLPSWSLGKWYSKEDYETLK 464 P K+ A +RK W+G +++L ++ W +KE+Y+ Sbjct: 323 LAPSTMKIKVVAPP---ERKYSVWIGGSILSSLSTFQ-QMWITKEEYDESG 369 >1C0F-A nrPDB Length = 368 Score = 273 bits (698), Expect = 1e-73, Method: Composition-based stats. Identities = 47/190 (24%), Positives = 90/190 (47%), Gaps = 12/190 (6%) Query: 6 KCVVIHNGSHRTVAGFSNVELPQCIIPSSYIKRTDEGGEAEFIFGTYNMIDAAAEKRNGD 65 + +VI NGS AGF+ + P+ + PS + R G+ + + A+ + G Sbjct: 6 QALVIDNGSGMCKAGFAGDDAPRAVFPS-IVGRPRHTGK-------DSYVGDEAQSKRGI 57 Query: 66 EVYTLVDSQGLPYNWDALEMQWRYLYDTQLKVSPEELPLVITMPATNGKPDMAILERYYE 125 G+ NWD +E W + + +L+V+PEE P+++T N K + E+ + Sbjct: 58 LTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANR---EKMTQ 114 Query: 126 LAFDKLNVPVFQIVIEPLAIALSMGKSSAFVIDIGASGCNVTPIIDGIVVKNAVVRSKFG 185 + F+ N P + I+ + + G+++ V+D G + PI +G + +A++R Sbjct: 115 IMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVSHTVPIYEGYALPHAILRLDLA 174 Query: 186 G-DFLDFQVH 194 G D D+ + Sbjct: 175 GRDLTDYMMK 184 Score = 87.6 bits (215), Expect = 1e-17, Method: Composition-based stats. Identities = 27/101 (26%), Positives = 49/101 (48%), Gaps = 5/101 (4%) Query: 365 TNVGDNNSTASSSNISPEQVYSLLLTNVIITGSTSLIEGMEQRIIKELSIRFPQ-YKLTT 423 + G + +T +S + L NV+++G T++ G+ R+ KEL+ P K+ Sbjct: 263 ESAGIHETTYNSIMKCDVDIRKDLYGNVVLSGGTTMFPGIADRMNKELTALAPSTMKIKI 322 Query: 424 FANQVMMDRKIQGWLGALTMANLPSWSLGKWYSKEDYETLK 464 A +RK W+G +A+L ++ W SKE+Y+ Sbjct: 323 IAPP---ERKYSVWIGGSILASLSTFQ-QMWISKEEYDESG 359 >4CBX-A nrPDB Length = 378 Score = 266 bits (680), Expect = 1e-71, Method: Composition-based stats. Identities = 46/189 (24%), Positives = 89/189 (47%), Gaps = 4/189 (2%) Query: 7 CVVIHNGSHRTVAGFSNVELPQCIIPSSYIKRTDEGGEAEFIFGTYNMIDAAAEKRNGDE 66 +V+ NGS +G + + P+C+ PS I + + A+ + G Sbjct: 9 ALVVDNGSGMVKSGLAGDDAPKCVFPS-IIGIPKMPNIMVGMEQKECYVGDEAQNKRGIL 67 Query: 67 VYTLVDSQGLPYNWDALEMQWRYLYDTQLKVSPEELPLVITMPATNGKPDMAILERYYEL 126 G+ NWD +E WR+ + +L+VSPEE P+++T N K + E+ ++ Sbjct: 68 TLKYPIEHGIVTNWDDMEKIWRHTFFNELRVSPEEHPVLLTEAPLNPKTNR---EKMTQI 124 Query: 127 AFDKLNVPVFQIVIEPLAIALSMGKSSAFVIDIGASGCNVTPIIDGIVVKNAVVRSKFGG 186 F+ +VP + I+ + + G+++ V+D G + PI +G V+ +A+ R+ G Sbjct: 125 MFESFDVPAMYVSIQAILSLYASGRTTGIVLDSGDGVTHTVPIYEGYVLPHAINRTDMAG 184 Query: 187 DFLDFQVHE 195 L + + + Sbjct: 185 RDLTYYMMK 193 Score = 71.4 bits (173), Expect = 9e-13, Method: Composition-based stats. Identities = 24/112 (21%), Positives = 51/112 (45%), Gaps = 9/112 (8%) Query: 354 NPNGLGTSHINTNVGDNNSTASSSNISPEQVYSLLLTNVIITGSTSLIEGMEQRIIKEL- 412 NP+ +G G + + S + L N++++G T++ + +R+ E+ Sbjct: 266 NPSLIGR----ECPGLHITAYQSIMKCDIDIRKELYNNIVLSGGTTMYNYIGERLTNEMT 321 Query: 413 SIRFPQYKLTTFANQVMMDRKIQGWLGALTMANLPSWSLGKWYSKEDYETLK 464 S+ P K+ A +RK W+G +++L ++ W +KE+Y+ Sbjct: 322 SLAPPSMKIKVIAPP---ERKYSVWIGGSILSSLSTFQ-KMWITKEEYDESG 369 >6F3A-A nrPDB Length = 376 Score = 244 bits (623), Expect = 6e-65, Method: Composition-based stats. Identities = 47/193 (24%), Positives = 87/193 (45%), Gaps = 5/193 (2%) Query: 3 LNRKCVVIHNGSHRTVAGFSNVELPQCIIPSSYIKRTDEGGEAEFIFGTYNMIDAAAEKR 62 + + VVI NGS AGF+ ++P+ P+ Y+ R I AE+ Sbjct: 7 IANQPVVIDNGSGVIKAGFAGDQIPKYCFPN-YVGRPKHVRVMAGALEGDIFIGPKAEEH 65 Query: 63 NGDEVYTLVDSQGLPYNWDALEMQWRYLYDT-QLKVSPEELPLVITMPATNGKPDMAILE 121 G G+ +W+ +E W+Y+Y QL+ EE P+++T N + + E Sbjct: 66 RGLLSIRYPMEHGIVKDWNDMERIWQYVYSKDQLQTFSEEHPVLLTEAPLNPRKNR---E 122 Query: 122 RYYELAFDKLNVPVFQIVIEPLAIALSMGKSSAFVIDIGASGCNVTPIIDGIVVKNAVVR 181 R E+ F+ NVP I ++ + + G+++ V+D G + PI +G + ++++R Sbjct: 123 RAAEVFFETFNVPALFISMQAVLSLYATGRTTGVVLDSGDGVTHAVPIYEGFAMPHSIMR 182 Query: 182 SKFGGDFLDFQVH 194 G + + Sbjct: 183 IDIAGRDVSRFLR 195 Score = 78.7 bits (192), Expect = 5e-15, Method: Composition-based stats. Identities = 23/98 (23%), Positives = 47/98 (47%), Gaps = 5/98 (5%) Query: 368 GDNNSTASSSNISPEQVYSLLLTNVIITGSTSLIEGMEQRIIKELSIRFPQ-YKLTTFAN 426 G + + S + L +N++++G ++L +G R++ E+ P+ K+ A Sbjct: 274 GIHEVLVFAIQKSDMDLRRTLFSNIVLSGGSTLFKGFGDRLLSEVKKLAPKDVKIRISAP 333 Query: 427 QVMMDRKIQGWLGALTMANLPSWSLGKWYSKEDYETLK 464 Q +R W+G +A+L ++ W SK++YE Sbjct: 334 Q---ERLYSTWIGGSILASLDTFK-KMWVSKKEYEEDG 367 >3ULE-B nrPDB Length = 394 Score = 230 bits (586), Expect = 1e-60, Method: Composition-based stats. Identities = 43/199 (21%), Positives = 81/199 (40%), Gaps = 11/199 (5%) Query: 4 NRKCVVIHNGSHRTVAGFSNVELPQCIIPS----SYIKRTDEGGEAEFIFGTYNMIDAAA 59 RK VV NG+ G++ P+ I P+ I+ T + G E + D A+ Sbjct: 5 GRKVVVCDNGTGFVKCGYAGSNFPEHIFPALVGRPIIRSTTKVGNIE--IKDLMVGDEAS 62 Query: 60 EKRNGDEVYTLVDSQGLPYNWDALEMQWRYLYDTQ-LKVSPEELPLVITMPATNGKPDMA 118 E R+ EV G+ NWD ++ W Y + + L + +++T P N + Sbjct: 63 ELRSMLEVN-YPMENGIVRNWDDMKHLWDYTFGPEKLNIDTRNCKILLTEPPMNPTKNR- 120 Query: 119 ILERYYELAFDKLNVPVFQIVIEPLAIALSMGKSSAFVIDIGASGCNVTPIIDGIVVKNA 178 E+ E+ F+ + I+ + + G + V+D G ++ P+ +G + + Sbjct: 121 --EKIVEVMFETYQFSGVYVAIQAVLTLYAQGLLTGVVVDSGDGVTHICPVYEGFSLPHL 178 Query: 179 VVRSKFGGDFLDFQVHERL 197 R G + + + L Sbjct: 179 TRRLDIAGRDITRYLIKLL 197 Score = 54.1 bits (128), Expect = 1e-07, Method: Composition-based stats. Identities = 16/113 (14%), Positives = 44/113 (38%), Gaps = 15/113 (13%) Query: 365 TNVGDNNSTASSSNISPEQVYSLLLTNVIITGSTSLIEGMEQRIIKELSI---------- 414 VG ++ + S +++++G +++ G+ R+ +EL Sbjct: 274 EGVGVAELLFNTIQAADIDTRSEFYKHIVLSGGSTMYPGLPSRLERELKQLYLERVLKGD 333 Query: 415 --RFPQYKLTTFANQVMMDRKIQGWLGALTMANLPSWSLGKWYSKEDYETLKR 465 + ++K+ + RK +LG +A++ W ++++Y+ Sbjct: 334 VEKLSKFKIRI---EDPPRRKHMVFLGGAVLADIMKDKDNFWMTRQEYQEKGV 383 >5NW4-X nrPDB Length = 417 Score = 178 bits (452), Expect = 4e-45, Method: Composition-based stats. Identities = 55/236 (23%), Positives = 84/236 (35%), Gaps = 29/236 (12%) Query: 5 RKCVVIHNGSHRTVAGFSNVELPQCIIPSSYIKRTDEGGEAEFIFGTYNMIDAAAEKRNG 64 + VVI G T GF+ P+CIIPS K G I N Sbjct: 13 KTAVVIDLGEAFTKCGFAGETGPRCIIPSVIKK-----------AGMPKPIKVVQYNINT 61 Query: 65 DEVYTLVDSQGLPYNWDALEMQWRYLYDTQLKVSPEELPLVITMPATNGKPDMAILERYY 124 +E+Y+ L+ LY L V+P + +V+ E Sbjct: 62 EELYSY------------LKEFIHILYFRHLLVNPRDRRVVVIESVLCPSHFR---ETLT 106 Query: 125 ELAFDKLNVPVFQIVIEPLAIALSMGKSSAFVIDIGASGCNVTPIIDGIVVKNAVVRSKF 184 + F VP + L L++G +SA V+D G V PI +GI V N Sbjct: 107 RVLFKYFEVPSVLLAPSHLMALLTLGINSAMVLDCGYRESLVLPIYEGIPVLNCWGALPL 166 Query: 185 GGDFLDFQVHERLAPLIKEENDMENMADEQKRSTDVWYEASTWIQQFKSTMLQVSE 240 GG L ++ +L +++ A EQ + + ++ K VS+ Sbjct: 167 GGKALHKELETQL---LEQCTVDTGAAKEQSLPSVMGSIPEGVLEDIKVRTCFVSD 219 Score = 55.6 bits (132), Expect = 5e-08, Method: Composition-based stats. Identities = 25/109 (22%), Positives = 35/109 (32%), Gaps = 7/109 (6%) Query: 364 NTNVGDNNSTASSSNISPEQVYSLLLTNVIITGSTSLIEGMEQRIIKELSIRF--PQYKL 421 N S P L N++I G TS++ G R++ E+ P+YK Sbjct: 275 NEEKSVATLILDSLMQCPIDTRKQLAENLVIIGGTSMLPGFLHRLLAEIRYLVEKPKYKK 334 Query: 422 TTFANQVMM-----DRKIQGWLGALTMANLPSWSLGKWYSKEDYETLKR 465 T + WLG L + SKE Y R Sbjct: 335 TLGTKTFRIHTPPAKANCVAWLGGAIFGALQDILGSRSVSKEYYNQTGR 383 >3DWL-A nrPDB Length = 427 Score = 160 bits (405), Expect = 1e-39, Method: Composition-based stats. Identities = 71/502 (14%), Positives = 149/502 (29%), Gaps = 141/502 (28%) Query: 8 VVIHNGSHRTVAGFSNVELPQCIIPSSYIKRTDEGGEAEFIFGTYNMI-----DAAAEKR 62 +++ NG+ + G++ + P + P+ R+ + + + + KR Sbjct: 8 IIMDNGTGYSKLGYAGNDAPSYVFPTVIATRSAGASSGPAVSSKPSYMASKGSGHLSSKR 67 Query: 63 NGDEV-----------------YTLVDSQGLPYNWDALEMQWRYLYDTQLKVSPEELPLV 105 +++ G NWD +E W+ L+ PE+ + Sbjct: 68 ATEDLDFFIGNDALKKASAGYSLDYPIRHGQIENWDHMERFWQQSLFKYLRCEPEDHYFL 127 Query: 106 ITMPATNGKPDMAILERYYELAFDKLNVPVFQIVIEP--------LAIALSMGKSSAFVI 157 +T P N + E E+ F+ N I ++ + ++ + V+ Sbjct: 128 LTEPPLNPPENR---ENTAEIMFESFNCAGLYIAVQAVLALAASWTSSKVTDRSLTGTVV 184 Query: 158 DIGASGCNVTPIIDGIVVKNAVVRSKFGGDFLDFQVHERLAPLIKEENDMENMADEQKRS 217 D G ++ P+ +G V+ +++ G + + V L+++ N Sbjct: 185 DSGDGVTHIIPVAEGYVIGSSIKTMPLAGRDVTYFVQS----LLRDRN------------ 228 Query: 218 TDVWYEASTWIQQFKSTMLQVSEKDLFELERYYKEQADIYAKQQ--EQLKQMDQQLQYTA 275 + L ER +E Y ++ + D++ Sbjct: 229 --------------------EPDSSLKTAERIKEEC--CYVCPDIVKEFSRFDRE----- 261 Query: 276 LTGSPNNPLVQKKNFLFKPLNKTLTLDLK-ECYQFAEYLFKPQLISDKFSPEDGLGPLMA 334 P K + T+D+ E + E F P++ S F Sbjct: 262 -------PDRYLKYASESITGHSTTIDVGFERFLAPEIFFNPEIASSDFL---------- 304 Query: 335 KSVKKAGASINSMKANTSTNPNGLGTSHINTNVGDNNSTASSSNISPEQVYSLLLTNVII 394 P + SP V L N+++ Sbjct: 305 -------------------TP-------------LPELVDNVVQSSPIDVRKGLYKNIVL 332 Query: 395 TGSTSLIEGMEQRIIKELSIRFPQYKLT-----------TFANQVMMDRKIQG-WLGALT 442 +G ++L + R+ ++L + N + R+ W G Sbjct: 333 SGGSTLFKNFGNRLQRDLKRIVDERIHRSEMLSGAKSGGVDVNVISHKRQRNAVWFGGSL 392 Query: 443 MANLPSWSLGKWYSKEDYETLK 464 +A P + ++K DYE Sbjct: 393 LAQTPEFG-SYCHTKADYEEYG 413 >1K8K-A nrPDB Length = 418 Score = 148 bits (372), Expect = 8e-36, Method: Composition-based stats. Identities = 62/328 (18%), Positives = 115/328 (35%), Gaps = 46/328 (14%) Query: 7 CVVIHNGSHRTVAGFSNVELPQCIIPSSY-------IKRTDEGGEAEFIFGTYNMIDAAA 59 V+ G+ T G++ PQ IIPS + + + + I A Sbjct: 7 ACVVDCGTGYTKLGYAGNTEPQFIIPSCIAIKESAKVGDQAQRRVMKGVDDLDFFIGDEA 66 Query: 60 EKRNGDEVYTLVDSQGLPYNWDALEMQWRYLYDTQLKVSPEELPLVITMPATNGKPDMAI 119 ++ G+ +WD +E + L+ PE+ ++T P N + Sbjct: 67 IEKPTYAT-KWPIRHGIVEDWDLMERFMEQVIFKYLRAEPEDHYFLLTEPPLNTPENR-- 123 Query: 120 LERYYELAFDKLNVPVFQIVIEPLAIALSMGKS--------SAFVIDIGASGCNVTPIID 171 E E+ F+ NVP I ++ + + S + VID G +V P+ + Sbjct: 124 -EYTAEIMFESFNVPGLYIAVQAVLALAASWTSRQVGERTLTGTVIDSGDGVTHVIPVAE 182 Query: 172 GIVVKNAVVRSKFGGDFLDFQVHERL---APLIKEENDMENM-ADEQKRS---------- 217 G V+ + + G + + + + L I E +E A +++ S Sbjct: 183 GYVIGSCIKHIPIAGRDITYFIQQLLRDREVGIPPEQSLETAKAVKERYSYVCPDLVKEF 242 Query: 218 TDVWYEASTWIQQFKSTMLQVSEKDLFE----LERYYKEQADIYAKQQEQLKQMDQQLQY 273 + S WI+Q+ T + K F ER+ +I+ + Q + Sbjct: 243 NKYDTDGSKWIKQY--TGINAISKKEFSIDVGYERFLG--PEIFFHPEFANPDFTQPISE 298 Query: 274 TALTGSPNNPLVQKKNFLFKPLNKTLTL 301 N P+ ++ PL K + L Sbjct: 299 VVDEVIQNCPIDVRR-----PLYKNIVL 321 Score = 47.5 bits (111), Expect = 1e-05, Method: Composition-based stats. Identities = 22/120 (18%), Positives = 45/120 (37%), Gaps = 23/120 (19%) Query: 360 TSHINTNVGDNNSTASSSNISPEQVYSLLLTNVIITGSTSLIEGMEQRIIKELSIRF-PQ 418 T I+ V + P V L N++++G +++ +R+ ++L + Sbjct: 293 TQPISEVVDEV------IQNCPIDVRRPLYKNIVLSGGSTMFRDFGRRLQRDLKRTVDAR 346 Query: 419 YKLTTFANQ--------------VMMDRKIQGWLGALTMANLPSWSLGKWYSKEDYETLK 464 KL+ + M R W G +A+ P + ++K+DYE + Sbjct: 347 LKLSEELSGGRLKPKPIDVQVITHHMQR-YAVWFGGSMLASTPEFY-QVCHTKKDYEEIG 404 >6GEJ-R nrPDB Length = 438 Score = 70.2 bits (170), Expect = 2e-12, Method: Composition-based stats. Identities = 80/509 (15%), Positives = 136/509 (26%), Gaps = 139/509 (27%) Query: 8 VVIHNGSHRTVAGFSNVELPQCIIPSSYIKRTDEGGEAEFIFGTYNMIDAAAEKRNGDEV 67 +VI NGS+ G PS+ K + + + Sbjct: 6 IVIDNGSYEIKFG-----------PSTNKKPFRALNALAKDKFGTSYLSNHIKNIKDISS 54 Query: 68 YTL--VDSQGLPYNWDALEMQWRYLYDTQLKVSP------EELPLVITMPATNGKPDMAI 119 T G W+ W Y + + LV + + Sbjct: 55 ITFRRPHELGQLTLWELESCIWDYCLFNPSEFDGFDLKEGKGHHLVASESCM---TLPEL 111 Query: 120 LERYYELAFDKLNVPVFQIVIEPLAIALS----------MGKSSAF-------------- 155 + ++ F++ + + + GK Sbjct: 112 SKHADQVIFEEYEFDSLFKSPVAVFVPFTKSYKGEMRTISGKDEDIDIVRGNSDSTNSTS 171 Query: 156 ------------------VIDIGASGCNVTPIIDGIVVKNAVVRSKFGGDFLDFQVHERL 197 VID G + + P++ GI AV + GG FL + E L Sbjct: 172 SESKNAQDSGSDYHDFQLVIDSGFNCTWIIPVLKGIPYYKAVKKLDIGGRFLTGLLKETL 231 Query: 198 APLIKEENDMENMADEQKRSTDVWYEASTWIQQFKSTMLQVSEKDLFELERYYKEQADIY 257 + NM DE + + K L VS F+ + + A Y Sbjct: 232 SFRHY------NMMDE-----------TILVNNIKEQCLFVSPVSYFDSFKTKDKHALEY 274 Query: 258 AKQQEQLKQMDQQLQYTALTGSPNNPLVQKKNFLFKPLNKTLTLDLKECYQFAEYLFKPQ 317 Q T+ G NP +K + P + + E + E F P+ Sbjct: 275 VLPDFQ----------TSFLGYVRNP---RKENVPLPEDAQIITLTDELFTIPETFFHPE 321 Query: 318 LISDKFSPEDGLGPLMAKSVKKAGASINSMKANTSTNPNGLGTSHINTNVGDNNSTASSS 377 + I G + S Sbjct: 322 -----------------------ISQITKP--------------------GIVEAILESL 338 Query: 378 NISPEQVYSLLLTNVIITGSTSLIEGMEQRIIKELSIRFPQYKLTTFANQVMMDRKIQGW 437 ++ PE V L++ N++ TG + QR+ EL + P T + D + GW Sbjct: 339 SMLPEIVRPLMVGNIVCTGGNFNLPNFAQRLAAELQRQLPT-DWTCHVSVPEGDCALFGW 397 Query: 438 LGALTMANLPSWSLGKWYSKEDYETLKRD 466 A S+ + ++E+Y D Sbjct: 398 EVMSQFAKTDSYRKAR-VTREEYYEHGPD 425 >6HTS-H nrPDB Length = 607 Score = 70.2 bits (170), Expect = 2e-12, Method: Composition-based stats. Identities = 36/191 (18%), Positives = 65/191 (34%), Gaps = 20/191 (10%) Query: 8 VVIHNGSHRTVAGFS--NVE---LPQCIIPSSYIKRTDEGGEAEFIFGTYNMIDAAAEKR 62 +V+ NGS + AG++ + P+ + G + +A Sbjct: 33 LVLDNGSFQVRAGWACPGQDPGPEPRLQFRAV----CARGRGGARGASGPQVGNALGSLE 88 Query: 63 NGDEVYTLVDSQGLPYNWDALEMQWRYLYDTQLKVSPE---ELPLVITMPATNGKPDMAI 119 + + +P N + E+ Y + L VS + + P+V+T N + Sbjct: 89 PLRWMLRSPFDRNVPVNLELQELLLDYSFQ-HLGVSSQGCVDHPIVLTEAVCNPLYSRQM 147 Query: 120 LERYYELAFDKLNVPVFQIVIEPLAIAL----SMGKSSAFVIDIGASGCNVTPIIDGIVV 175 EL F+ +P I+ L S +I G +V PI++G + Sbjct: 148 ---MSELLFECYGIPKVAYGIDSLFSFYHNKPKNSMCSGLIISSGYQCTHVLPILEGRLD 204 Query: 176 KNAVVRSKFGG 186 R GG Sbjct: 205 AKNCKRINLGG 215 Score = 47.5 bits (111), Expect = 1e-05, Method: Composition-based stats. Identities = 26/112 (23%), Positives = 48/112 (42%), Gaps = 5/112 (4%) Query: 365 TNVGDNNSTASSSNISPEQVYSLLLTNVIITGSTSLIEGMEQRIIKELSIRFPQYKLT-T 423 G + + P+ + +L+ NV +TG ++ GM+ R+ KEL P + Sbjct: 464 EQAGIAETLQYILDRYPKDIQEMLVQNVFLTGGNTMYPGMKARMEKELLEMRP---FRSS 520 Query: 424 FANQVMMDRKIQGWLGALTMANLPSWSLGKWYSKEDYETLKRDR-KQSQATN 474 F Q+ + + W GA A W ++++YE + K+ A+N Sbjct: 521 FQVQLASNPVLDAWYGARDWALNHLDDNEVWITRKEYEEKGGEYLKEHCASN 572 >4AM6-A nrPDB Length = 655 Score = 64.5 bits (155), Expect = 1e-10, Method: Composition-based stats. Identities = 66/413 (15%), Positives = 142/413 (34%), Gaps = 53/413 (12%) Query: 21 FSNVELPQCIIPSSYIKRTDEGGEAEFIFGTYNMIDAAAEKRNGDEVYTLVDSQGLPYNW 80 + + +C+ I++ GG F + ++ E+ + Sbjct: 158 YYGSDALRCVDEKFVIRKPFRGG--SFNVKSP-------YYKSLAELIS----------- 197 Query: 81 DALEMQWRYLYDTQ-LKVSP---EELPLVITMPATNGKPDMAILERYYELAFDKLNVPVF 136 + + +++ L V P + +V+ +P K +E + + +L Sbjct: 198 -DVTKLLEHALNSETLNVKPTKFNQYKVVLVIPDIFKKSH---VETFIRVLLTELQFQAV 253 Query: 137 QIVIEPLAIALSMGKSSAF-VIDIGASGCNVTPIIDGIVVKNAVVRSKFGGDFLDFQVHE 195 I+ E LA G S++ V++IGA+ + + +G V++++ + +GGD + Sbjct: 254 AIIQESLATCYGAGISTSTCVVNIGAAETRIACVDEGTVLEHSAITLDYGGDDI-----T 308 Query: 196 RLAPLIKEENDMENMADEQKRSTDVWYEASTWIQQFKSTMLQVSEKDLFELERYYKEQAD 255 RL L ++D D + S W A + F + L+ Q Sbjct: 309 RLFALFLLQSDFPL-QDWKIDSKHGWLLAERLKKNFTTFQDADVAVQLYNFMNRSPNQ-- 365 Query: 256 IYAKQQEQLK-QMDQQLQYTALTGSPNNPLVQKKNFLFKPLNKTLTLDL-KECYQFAEYL 313 E+ + ++ ++ L + K N +L L + F L Sbjct: 366 ----PTEKYEFKLFDEVMLAPLALFFPQIFKLIRTSSHK--NSSLEFQLPESRDLFTNEL 419 Query: 314 FKPQLISDKFSPEDGLGPLMAKSVK--KAGASINSMKANTSTNPNGLGTSHINTNVG--- 368 +S S E L + +K +++ P G + + N Sbjct: 420 NDWNSLSQFESKEGNLYCDLNDDLKILNRILDAHNIIDQLQDKPENYGNT-LKENFAPLE 478 Query: 369 --DNNSTASSSNISPEQVYSLLLTNVIITGSTSLIEGMEQRIIKELSIRFPQY 419 S A++S + + +N++I G +S I ++ + ++I P Sbjct: 479 KAIVQSIANASITADVTRMNSFYSNILIVGGSSKIPALDFILTDRINIWRPSL 531 >4FO0-A nrPDB Length = 593 Score = 47.1 bits (110), Expect = 2e-05, Method: Composition-based stats. Identities = 21/131 (16%), Positives = 48/131 (36%), Gaps = 6/131 (4%) Query: 62 RNGDEVYTLVDSQGLPYNWDALEMQWRYLYDTQLKVSPEEL---PLVITMPATNGKPDMA 118 R G L +E+ W + L++ ++L ++ +P + Sbjct: 156 RRGQLNIHPGPGGSLTAVLADIEVIWSHAIQKYLEIPLKDLKYYRCILLIPDIY---NKQ 212 Query: 119 ILERYYELAFDKLNVPVFQIVIEPLAIALSMGKSSAFVIDIGASGCNVTPIIDGIVVKNA 178 ++ + K+ + E + G SS ++D+G +V + DG+ +N Sbjct: 213 HVKELVNMILMKMGFSGIVVHQESVCATYGSGLSSTCIVDVGDQKTSVCCVEDGVSHRNT 272 Query: 179 VVRSKFGGDFL 189 + +GG + Sbjct: 273 RLCLAYGGSDV 283 Score = 30.9 bits (68), Expect = 1.4, Method: Composition-based stats. Identities = 12/40 (30%), Positives = 18/40 (45%), Gaps = 1/40 (2%) Query: 8 VVIHNGSHRTVAGFSNVELPQCIIPSSYIKRTDEGGEAEF 47 +VIH GS G + LP I P +R + G+ + Sbjct: 18 IVIHPGSTTLRIGRATDTLPASI-PHVIARRHKQQGQPLY 56 >5LY3-A nrPDB Length = 432 Score = 45.6 bits (106), Expect = 4e-05, Method: Composition-based stats. Identities = 25/177 (14%), Positives = 56/177 (31%), Gaps = 17/177 (9%) Query: 10 IHNGSHRTVAGFSNVELPQCI---------IP-SSYIKRTDEGGEAEFIFGTYNMIDAAA 59 + G+ G + P+ + +P S ++ + + G + + Sbjct: 16 VDFGTSYVKYGPITLNEPKMVQTRGLFLRDLPESVKMRIPPDVLARGLVVGDEEVRKYLS 75 Query: 60 EKRNGDEVYTLVDSQGLPYN-----WDALEMQWRYLYDTQLKVSPE--ELPLVITMPATN 112 R+ G+ W L+ RY PE + + + A Sbjct: 76 SVRDVQRNLKYPLKDGVARRDDEEAWRVLKELARYTLAQFPVSDPEFAGWLVAVALSALA 135 Query: 113 GKPDMAILERYYELAFDKLNVPVFQIVIEPLAIALSMGKSSAFVIDIGASGCNVTPI 169 + Y+ + + I+ +PLA+A++ + +++ G V PI Sbjct: 136 PDYMYKAIFDIYDELASEFKIYAVTILPQPLAVAIAENAVNCVIVEGGHGNIQVAPI 192 >4I6M-B nrPDB Length = 439 Score = 45.2 bits (105), Expect = 7e-05, Method: Composition-based stats. Identities = 36/211 (17%), Positives = 75/211 (35%), Gaps = 32/211 (15%) Query: 25 ELPQCIIPSSYIKRTDEGGEAEFIFGTYNMIDAAAEKRNGDEVYTLVDSQGLPYNWDALE 84 +P+ IP+ + T + G + + K N E+ G + A Sbjct: 31 TVPELEIPTQIYRTTRQDGSYTYH---------STNKDNKAELIK-PIQNGEIIDISAFT 80 Query: 85 MQWRYLY-----------DTQLKVSPEELPLVITMPATNGKPDMAILERYYELAFDKLNV 133 R ++ + +PL++ T+ + LE + F+ L + Sbjct: 81 QFLRLIFVSILSDRANKNQDAFEAELSNIPLLLI---THHSWSQSDLEIITQYVFESLEI 137 Query: 134 PVFQIVIEPLAIALSM-GKSSAFVIDIGASGCNVTPIIDGIVVKNAVVRSKFGGDFLDFQ 192 + LA SM + +ID+G ++ PI+D + + V GG ++ Sbjct: 138 NNLIQLPASLAATYSMISLQNCCIIDVGTHHTDIIPIVDYAQLDHLVSSIPMGGQSINDS 197 Query: 193 VHERLA-------PLIKEENDMENMADEQKR 216 + + L +K+ E ++D+ K+ Sbjct: 198 LKKLLPQWDDDQIESLKKSPIFEVLSDDAKK 228 >3WEE-A nrPDB Length = 476 Score = 44.8 bits (104), Expect = 8e-05, Method: Composition-based stats. Identities = 36/211 (17%), Positives = 75/211 (35%), Gaps = 32/211 (15%) Query: 25 ELPQCIIPSSYIKRTDEGGEAEFIFGTYNMIDAAAEKRNGDEVYTLVDSQGLPYNWDALE 84 +P+ IP+ + T + G + + K N E+ G + A Sbjct: 40 TVPELEIPTQIYRTTRQDGSYTYH---------STNKDNKAELIK-PIQNGEIIDISAFT 89 Query: 85 MQWRYLY-----------DTQLKVSPEELPLVITMPATNGKPDMAILERYYELAFDKLNV 133 R ++ + +PL++ T+ + LE + F+ L + Sbjct: 90 QFLRLIFVSILSDRANKNQDAFEAELSNIPLLLI---THHSWSQSDLEIITQYVFESLEI 146 Query: 134 PVFQIVIEPLAIALSM-GKSSAFVIDIGASGCNVTPIIDGIVVKNAVVRSKFGGDFLDFQ 192 + LA SM + +ID+G ++ PI+D + + V GG ++ Sbjct: 147 NNLIQLPASLAATYSMISLQNCCIIDVGTHHTDIIPIVDYAQLDHLVSSIPMGGQSINDS 206 Query: 193 VHERLA-------PLIKEENDMENMADEQKR 216 + + L +K+ E ++D+ K+ Sbjct: 207 LKKLLPQWDDDQIESLKKSPIFEVLSDDAKK 237 >3H1Q-A nrPDB Length = 272 Score = 30.9 bits (68), Expect = 1.2, Method: Composition-based stats. Identities = 12/37 (32%), Positives = 19/37 (51%) Query: 136 FQIVIEPLAIALSMGKSSAFVIDIGASGCNVTPIIDG 172 +V EP+A A ++G + V+DIG + I G Sbjct: 123 VTLVDEPVAAARALGINDGIVVDIGGGTTGIAVIEKG 159 >6FHI-C nrPDB Length = 809 Score = 30.6 bits (67), Expect = 1.7, Method: Composition-based stats. Identities = 19/114 (16%), Positives = 39/114 (34%), Gaps = 13/114 (11%) Query: 38 RTDEGGEAEFIFGTY-NMIDAAAEKRNGDEVYTLVDSQGLPYNWDALEMQWR---YLYDT 93 +E EA+ N + + NG E + NW+ L+ QW + Sbjct: 523 SPEEVSEAQGQEKLPINYNSSLMWEVNGPESILTNTYHWIIKNWELLKTQWMTDPTVLYN 582 Query: 94 QLKVSPEELPLVITMPATNGKPDMAILERYYELAFDKL-NVPVFQIVIEPLAIA 146 +++ P + K + AI + F ++ +V I+ + + Sbjct: 583 RIEFEPFQ--------TLIPKGNRAIYSGFTRTLFQQMRDVEGTFDSIQIIKLL 628 >5WUA-A nrPDB Length = 681 Score = 29.8 bits (65), Expect = 2.7, Method: Composition-based stats. Identities = 26/155 (16%), Positives = 49/155 (31%), Gaps = 8/155 (5%) Query: 160 GASGCNVTPIIDGIVVKNAVVRSKFGGDFLDFQVHERLAPLIKEENDMENMADEQKRSTD 219 G V P+I V+ + L H+ L ++ E +E + T Sbjct: 246 GNGIFLVAPLIIYHVIDSNSPLYDLAPSDLHH--HQDLEIIVILEGVVETTGITTQARTS 303 Query: 220 VWYEASTWIQQFKSTMLQVSEKDLFELERYYKEQA-DIYAKQQEQLKQMDQQLQYTALTG 278 + W Q+F + + + + ++ QL + L L Sbjct: 304 YLADEILWGQRFVPIVAEEDGRYSVDYSKFGNTIKVPTPLCTARQLDEDRSLLDALTLAS 363 Query: 279 S-----PNNPLVQKKNFLFKPLNKTLTLDLKECYQ 308 S + V K F +L+L+L+ +Q Sbjct: 364 SRGPLRKRSVAVAKAKPKFSISPDSLSLELEVLFQ 398 >2O1M-A nrPDB Length = 258 Score = 28.2 bits (61), Expect = 8.3, Method: Composition-based stats. Identities = 11/32 (34%), Positives = 15/32 (46%) Query: 391 NVIITGSTSLIEGMEQRIIKELSIRFPQYKLT 422 N+ + G + +IKEL R P YK T Sbjct: 28 NICFIDEKGDLTGYDVELIKELDKRLPHYKFT 59 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.310 0.122 0.314 Lambda K H 0.267 0.0361 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 15,523,139 Number of Sequences: 36641 Number of extensions: 573750 Number of successful extensions: 1956 Number of sequences better than 10.0: 27 Number of HSP's better than 10.0 without gapping: 41 Number of HSP's successfully gapped in prelim test: 25 Number of HSP's that attempted gapping in prelim test: 1804 Number of HSP's gapped (non-prelim): 104 length of query: 477 length of database: 10,336,785 effective HSP length: 101 effective length of query: 376 effective length of database: 6,636,044 effective search space: 2495152544 effective search space used: 2495152544 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.4 bits) S2: 60 (27.9 bits)