BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q12068 (342 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 4PVC-A nrPDB 706 0.0 5B6K-A nrPDB 421 e-118 5YWN-A nrPDB 294 3e-80 4QUK-A nrPDB 117 9e-27 4R1T-A nrPDB 112 3e-25 1ZZE-A nrPDB 108 5e-24 4R1U-A nrPDB 105 4e-23 3HFS-A nrPDB 103 1e-22 2NNL-D nrPDB 88 7e-18 2P4H-X nrPDB 65 6e-11 1GY8-A nrPDB 47 2e-05 4LIS-A nrPDB 41 8e-04 4WKG-A nrPDB 40 0.002 5CDY-A nrPDB 39 0.004 3RSH-A nrPDB 35 0.037 5JRE-A nrPDB 35 0.065 1Q7C-A nrPDB 35 0.067 6BI4-A nrPDB 32 0.32 2J3K-A nrPDB 32 0.33 1UDA-A nrPDB 32 0.33 6BWL-A nrPDB 32 0.43 2C54-A nrPDB 32 0.47 3MYR-B nrPDB 31 0.60 4WOK-A nrPDB 31 0.66 1I3M-A nrPDB 30 1.3 2Q1W-A nrPDB 30 2.0 1E5Q-A nrPDB 29 2.5 5XWI-A nrPDB 29 2.9 6FKI-F nrPDB 28 4.6 4R7O-A nrPDB 28 4.6 3F9I-A nrPDB 28 5.8 2AXQ-A nrPDB 28 6.4 3ENK-A nrPDB 28 8.3 >4PVC-A nrPDB Length = 342 Score = 706 bits (1821), Expect = 0.0, Method: Compositional matrix adjust. Identities = 342/342 (100%), Positives = 342/342 (100%) Query: 1 MSVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISK 60 MSVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISK Sbjct: 1 MSVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISK 60 Query: 61 LDAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAADSVE 120 LDAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAADSVE Sbjct: 61 LDAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAADSVE 120 Query: 121 RVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAAWEFL 180 RVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAAWEFL Sbjct: 121 RVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAAWEFL 180 Query: 181 EENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLSPEDKIPELFGGYI 240 EENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLSPEDKIPELFGGYI Sbjct: 181 EENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLSPEDKIPELFGGYI 240 Query: 241 DVRDVAKAHLVAFQKRETIGQRLIVSEARFTMQDVLDILNEDFPVLKGNIPVGKPGSGAT 300 DVRDVAKAHLVAFQKRETIGQRLIVSEARFTMQDVLDILNEDFPVLKGNIPVGKPGSGAT Sbjct: 241 DVRDVAKAHLVAFQKRETIGQRLIVSEARFTMQDVLDILNEDFPVLKGNIPVGKPGSGAT 300 Query: 301 HNTLGATLDNKKSKKLLGFKFRNLKETIDDTASQILKFEGRI 342 HNTLGATLDNKKSKKLLGFKFRNLKETIDDTASQILKFEGRI Sbjct: 301 HNTLGATLDNKKSKKLLGFKFRNLKETIDDTASQILKFEGRI 342 >5B6K-A nrPDB Length = 366 Score = 421 bits (1083), Expect = e-118, Method: Compositional matrix adjust. Identities = 212/341 (62%), Positives = 256/341 (75%), Gaps = 4/341 (1%) Query: 2 SVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKL 61 +VFVSGA GFIAQH+V LL ++YKVIGS RS EK ++L F+ E+V DIS Sbjct: 23 TVFVSGATGFIAQHVVRQLLDQNYKVIGSVRSAEKGDHLKNVIFKGGDFNYEIVKDISDP 82 Query: 62 DAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAADSVER 121 AFDHVF+KHGKDIK+VLHTASPF F+ TD E+DLLIPAVNG KGIL SIKKYAA +VER Sbjct: 83 TAFDHVFEKHGKDIKVVLHTASPFHFNTTDIEKDLLIPAVNGTKGILESIKKYAAQTVER 142 Query: 122 VVLTSSYAA---VFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAAWE 178 VV+TSS+AA DM D S T EESWN TWESCQSDP+ YCGSKKFAEKAAW+ Sbjct: 143 VVVTSSFAANTSTVDMFYAKDSSKTITEESWNQDTWESCQSDPIRGYCGSKKFAEKAAWD 202 Query: 179 FLEENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLSPEDKIPELFGG 238 F N+DSVKF+L+ +NPVYVFGPQ + + KK LNTS E++NSL+HL +D +PE GG Sbjct: 203 FYNANKDSVKFKLSIINPVYVFGPQNYVEPGKKILNTSSEVINSLVHLKKDDPLPEFAGG 262 Query: 239 YIDVRDVAKAHLVAFQKRETIGQRLIVSEARFTMQDVLDILNEDFPVLKGNIPVGKPGSG 298 +IDVRDVAKAH++AFQK E I QRL++ FT Q +LDI+NE FP LKG IP GKPG+G Sbjct: 263 HIDVRDVAKAHILAFQKDELIEQRLMLHAGLFTTQTLLDIINEQFPELKGKIPAGKPGTG 322 Query: 299 ATHNTLGATLDNKKSKKLLGFKFRNLKETIDDTASQILKFE 339 + L +DN K+KKLLGF+F +LK+ + DT SQIL+ E Sbjct: 323 NPDDAL-TPVDNSKTKKLLGFEFIDLKKDLYDTISQILEAE 362 >5YWN-A nrPDB Length = 334 Score = 294 bits (753), Expect = 3e-80, Method: Compositional matrix adjust. Identities = 153/339 (45%), Positives = 228/339 (67%), Gaps = 8/339 (2%) Query: 2 SVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKL 61 SVFVSGA G++AQ I+ L+L + YKV+GS RS+EK NL + +G++ FS EVV + + Sbjct: 4 SVFVSGATGYLAQQIIALVLSKGYKVVGSVRSEEKGANLKKLYGDD--FSYEVVKVLEQK 61 Query: 62 DAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAADSVER 121 AFD +KH ++ I LHTASP F++ D+E+++LIPA+NG K +L SIK A + R Sbjct: 62 GAFDEALKKH-PEVTIFLHTASPVTFEVEDTEKEILIPAINGTKYVLQSIKD-VAPQITR 119 Query: 122 VVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAAWEFLE 181 VV TSS A+ + + +E SW+ ++E ++ V AY GSK+FAE+AAWEF+E Sbjct: 120 VVYTSSVVAMSVPEELGSPDVVLSEASWSSLSYEQSKTHGVLAYFGSKQFAERAAWEFVE 179 Query: 182 ENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLSPEDKIPELFGGYID 241 + + + F L+ VNPVY+FGPQ D++VK LN S E+VNS++ L+ +D +P G +ID Sbjct: 180 QEKPN--FALSTVNPVYIFGPQAKDEEVKGTLNHSAEMVNSVLKLNKDDDVPATTGTFID 237 Query: 242 VRDVAKAHLVAFQKRETIGQRLIVSEARFTMQDVLDILNEDFPVLKGNIPVGKPGSGATH 301 VRDVAKAHL AF+K E G+RL++S RF Q +LD++ ++FP L +PVGKP S Sbjct: 238 VRDVAKAHLAAFEKDEAKGERLLLSNTRFNGQTLLDVVRKNFPQLADKLPVGKPHSD--D 295 Query: 302 NTLGATLDNKKSKKLLGFKFRNLKETIDDTASQILKFEG 340 + ++KK+KK+LGF++ + + ++ D+ Q+LK +G Sbjct: 296 FSAFKEWNDKKTKKILGFEYFDFETSVVDSIKQVLKVQG 334 >4QUK-A nrPDB Length = 319 Score = 117 bits (292), Expect = 9e-27, Method: Compositional matrix adjust. Identities = 93/289 (32%), Positives = 150/289 (51%), Gaps = 27/289 (9%) Query: 3 VFVSGANGFIAQHIVDLLLKEDYKVIGSARSQ---EKAENLTEAFGNNPKFSMEVVPDIS 59 V V+GA+G+IA +V LLL Y V + R +K ++L + G + + ++ Sbjct: 3 VCVTGASGYIASWLVRLLLHRGYTVKATVRDPNDPKKVDHLVKLDGAKERLQL-FKANLL 61 Query: 60 KLDAFDHVFQK-HGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAADS 118 + AFD V Q HG V HTASPF D+ D + +L+ PA+ G +L+S K + S Sbjct: 62 EEGAFDSVVQGCHG-----VFHTASPFYHDVKDPQAELIDPALKGTLNVLNSCAK--SPS 114 Query: 119 VERVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAAWE 178 ++RVVLTSS AAV K + +E + A + C + Y S AE+AAW+ Sbjct: 115 LKRVVLTSSIAAVAYNGKPRTPDVVVDETWFTDADF--CAKSNL-WYVVSATLAEEAAWK 171 Query: 179 FLEENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLSPEDKIPELFGG 238 F++EN ++ +NP V GP + + LNTS + +L++ + P G Sbjct: 172 FVKENN----IDMVTINPAMVIGPLL-----QPVLNTSAAAILNLINGA--QTFPNASFG 220 Query: 239 YIDVRDVAKAHLVAFQKRETIGQRLIVSEARFTMQDVLDILNEDFPVLK 287 +++V+DVA AH++A++ G+ +V E +V+ IL E +P L+ Sbjct: 221 WVNVKDVANAHILAYENASASGRHCLV-ERVAHYSEVVRILRELYPSLQ 268 >4R1T-A nrPDB Length = 337 Score = 112 bits (280), Expect = 3e-25, Method: Compositional matrix adjust. Identities = 100/337 (29%), Positives = 163/337 (48%), Gaps = 37/337 (10%) Query: 3 VFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAEN--LTEAFGNNPKFSMEVVPDISK 60 V V+GA GFIA +V +LL++ Y V G+ R+ + +N L E G + ++ K Sbjct: 13 VCVTGAGGFIASWLVKILLEKGYTVRGTVRNPDDPKNGHLRELEGAKERLTL------CK 66 Query: 61 LDAFDHVFQKHG-KDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAADSV 119 D D+ + V HTASP +TD ++ PAV G K ++++ A +V Sbjct: 67 ADLLDYQSLREAINGCDGVFHTASP----VTDDPEQMVEPAVIGTKNVINAA---AEANV 119 Query: 120 ERVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAAWEF 179 RVV TSS AV+ M D +E W+ + C++ N YC K AE+AAWE Sbjct: 120 RRVVFTSSIGAVY-MDPNRDPETVVDETCWSDPDF--CKNTK-NWYCYGKMVAEQAAWEE 175 Query: 180 LEENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLSPEDKI-PELFGG 238 +E +L +NPV V GP + + +N S +++ L +L+ K Sbjct: 176 AKEK----GVDLVVINPVLVQGPLL-----QTTVNAS--VLHILKYLTGSAKTYANSVQA 224 Query: 239 YIDVRDVAKAHLVAFQKRETIGQRLIVSEARFTMQDVLDILNEDFPVLKGNIPVGKPGSG 298 Y+DV+DVA AH++ ++ E G R + +E+ DV++IL++ FP P+ S Sbjct: 225 YVDVKDVALAHILLYETPEASG-RYLCAESVLHRGDVVEILSKFFP----EYPIPTKCSD 279 Query: 299 ATHNTLGATLDNKKSKKLLGFKFRNLKETIDDTASQI 335 T + + + K LG +F +K+ + +T + Sbjct: 280 VTKPRVKPYKFSNQKLKDLGLEFTPVKQCLYETVKSL 316 >1ZZE-A nrPDB Length = 342 Score = 108 bits (269), Expect = 5e-24, Method: Compositional matrix adjust. Identities = 101/339 (29%), Positives = 160/339 (47%), Gaps = 28/339 (8%) Query: 3 VFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAF-GNNP-KFSMEVVPDISK 60 V V+GANGF+A H+V+ LL+ YKV G+ARS K NL + + P +F VV D+ K Sbjct: 14 VLVTGANGFVASHVVEQLLEHGYKVRGTARSASKLANLQKRWDAKYPGRFETAVVEDMLK 73 Query: 61 LDAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAAD-SV 119 A+D V K V H AS F ++ +++ PA+ G L++++ AA SV Sbjct: 74 QGAYDEVI----KGAAGVAHIASVVSF--SNKYDEVVTPAIGGT---LNALRAAAATPSV 124 Query: 120 ERVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESC----QSDPVNA---YCGSKKFA 172 +R VLTSS + + K N + + +E+SWN + + +SDP + Y SK A Sbjct: 125 KRFVLTSSTVSAL-IPKPNVEGIYLDEKSWNLESIDKAKTLPESDPQKSLWVYAASKTEA 183 Query: 173 EKAAWEFLEENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLSPEDKI 232 E AAW+F++EN+ F L AV P Y G +FD + + + + +SP + Sbjct: 184 ELAAWKFMDENKP--HFTLNAVLPNYTIG-TIFDPETQSGSTSGWMMSLFNGEVSPALAL 240 Query: 233 -PELFGGYIDVRDVAKAHLVAFQKRETIGQRLIVSEARFTMQDVLDILNEDFPVLKGNIP 291 P + Y+ D+ HL + +R+ + F VL + +P P Sbjct: 241 MPPQY--YVSAVDIGLLHLGCLVLPQIERRRVYGTAGTFDWNTVLATFRKLYP--SKTFP 296 Query: 292 VGKPGSGATHNTLGATLDNKKSKKLLGFKFRNLKETIDD 330 P G + + K L +R+++E+I D Sbjct: 297 ADFPDQGQDLSKFDTAPSLEILKSLGRPGWRSIEESIKD 335 >4R1U-A nrPDB Length = 349 Score = 105 bits (261), Expect = 4e-23, Method: Compositional matrix adjust. Identities = 100/340 (29%), Positives = 156/340 (45%), Gaps = 41/340 (12%) Query: 2 SVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAEN--LTEAFGNNPKFSMEVVPDIS 59 +V V+GA GFIA +V LLL+ Y V G+ R+ E +N L E G + ++ V D+ Sbjct: 29 TVCVTGAGGFIASWLVKLLLERGYTVRGTVRNPEDPKNGHLKELEGARERLTLHKV-DLL 87 Query: 60 KLDAFDHVFQK-HGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAADS 118 L + V HG V HTASP +TD+ ++L PAVNG K + I A Sbjct: 88 DLQSIQSVVHGCHG-----VFHTASP----VTDNPDEMLEPAVNGTKNV---IIASAEAK 135 Query: 119 VERVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAAWE 178 V RVV TSS V+ M + + +E W + E C++ N YC K AE++AW+ Sbjct: 136 VRRVVFTSSIGTVY-MDPNTSRDVVVDESYW--SDLEHCKNTK-NWYCYGKTVAEQSAWD 191 Query: 179 FLEENRDSVKFELTAVNPVYVFGPQMFDKDVK--KHLNTSCE-LVNSLMHLSPEDKIPEL 235 +EN+ + V + P + + K+LN + + VN+ Sbjct: 192 IAKENQVDLVVVNPVVVLGPLLQPTINASTIHILKYLNGAAKTYVNATQ----------- 240 Query: 236 FGGYIDVRDVAKAHLVAFQKRETIGQRLIVSEARFTMQDVLDILNEDFPVLKGNIPVGKP 295 Y+ V+DVA AHL+ ++ G R I E +V++IL + FP P+ Sbjct: 241 --SYVHVKDVALAHLLVYETNSASG-RYICCETALHRGEVVEILAKYFP----EYPLPTK 293 Query: 296 GSGATHNTLGATLDNKKSKKLLGFKFRNLKETIDDTASQI 335 S + + + + K LG +F +K+ + DT + Sbjct: 294 CSDEKNPRVKPYKFSNQKLKDLGLEFTPVKQCLYDTVRSL 333 >3HFS-A nrPDB Length = 338 Score = 103 bits (256), Expect = 1e-22, Method: Compositional matrix adjust. Identities = 84/291 (28%), Positives = 136/291 (46%), Gaps = 25/291 (8%) Query: 5 VSGANGFIAQHIVDLLLKEDYKVIGSAR---SQEKAENLTE--AFGNNPKFSMEVVPDIS 59 V G GF+A +V LLL++ Y V + R +Q+K +L E G+ F ++ ++S Sbjct: 14 VVGGTGFVASLLVKLLLQKGYAVNTTVRDPDNQKKVSHLLELQELGDLKIFRADLTDELS 73 Query: 60 KLDAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAADSV 119 F+ V H A+P F D E D++ PA+ GV ++ + + A SV Sbjct: 74 --------FEAPIAGCDFVFHVATPVHFASEDPENDMIKPAIQGVVNVMKACTR--AKSV 123 Query: 120 ERVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAAWEF 179 +RV+LTSS AAV + + + L +E++W + + P Y SK AEKAAW+F Sbjct: 124 KRVILTSSAAAV-TINQLDGTGLVVDEKNWTDIEFLTSAKPPTWGYPASKTLAEKAAWKF 182 Query: 180 LEENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLSPEDKIPELFGGY 239 EEN +L V P + G + DV + + L+ L K ++ G Sbjct: 183 AEENN----IDLITVIPTLMAGSSL-TSDVPSSIGLAMSLITGNEFLINGMKGMQMLSGS 237 Query: 240 ID---VRDVAKAHLVAFQKRETIGQRLIVSEARFTMQDVLDILNEDFPVLK 287 + V DV +AH+ +K G R I A ++ ++ L++ +P K Sbjct: 238 VSIAHVEDVCRAHIFVAEKESASG-RYICCAANTSVPELAKFLSKRYPQYK 287 >2NNL-D nrPDB Length = 337 Score = 87.8 bits (216), Expect = 7e-18, Method: Compositional matrix adjust. Identities = 85/326 (26%), Positives = 142/326 (43%), Gaps = 32/326 (9%) Query: 2 SVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVV---PDI 58 +V V+GA+GFI +V LL+ Y V + R + + + PK + D+ Sbjct: 7 TVCVTGASGFIGSWLVMRLLERGYTVRATVRDPTNVKKVKHLL-DLPKAETHLTLWKADL 65 Query: 59 SKLDAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAADS 118 + +FD K V H A+P F+ D E +++ P + G+ GI+ S AA + Sbjct: 66 ADEGSFDEAI----KGCTGVFHVATPMDFESKDPENEVIKPTIEGMLGIMKSCA--AAKT 119 Query: 119 VERVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNA--YCGSKKFAEKAA 176 V R+V TSS V + + ++E W+ E C++ + A Y SK AE+AA Sbjct: 120 VRRLVFTSSAGTV---NIQEHQLPVYDESCWSDM--EFCRAKKMTAWMYFVSKTLAEQAA 174 Query: 177 WEFLEENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLSPEDKIPELF 236 W++ +EN + + P V GP + + + + H S + Sbjct: 175 WKYAKENN----IDFITIIPTLVVGPFIMSSMPPSLITALSPITGNEAHYSIIRQ----- 225 Query: 237 GGYIDVRDVAKAHLVAFQKRETIGQRLIVSEARFTMQDVLDILNEDFPVLKGNIPVGKPG 296 G ++ + D+ AH+ F+ + G R I S + D+ +L E +P + NIP Sbjct: 226 GQFVHLDDLCNAHIYLFENPKAEG-RYICSSHDCIILDLAKMLREKYP--EYNIPT--EF 280 Query: 297 SGATHNTLGATLDNKKSKKLLGFKFR 322 G N +KK LGF+F+ Sbjct: 281 KGVDENLKSVCFSSKKLTD-LGFEFK 305 >2P4H-X nrPDB Length = 322 Score = 64.7 bits (156), Expect = 6e-11, Method: Compositional matrix adjust. Identities = 90/354 (25%), Positives = 149/354 (42%), Gaps = 49/354 (13%) Query: 3 VFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEV---VPDIS 59 V V+G GF+ I+ LL+ Y V + R+ + + N P S ++ D+S Sbjct: 4 VCVTGGTGFLGSWIIKSLLENGYSVNTTIRADPERKRDVSFLTNLPGASEKLHFFNADLS 63 Query: 60 KLDAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAADSV 119 D+F + + HTASP F +++ E + V+G GIL + + +V Sbjct: 64 NPDSFAAAIEGCVG----IFHTASPIDFAVSEPEEIVTKRTVDGALGILKACVN--SKTV 117 Query: 120 ERVVLTSSYAAVFDMAKENDKSLTFNEESWN---------PATWESCQSDPVNAYCGSKK 170 +R + TSS +AV K+ D +E W+ P W Y SK Sbjct: 118 KRFIYTSSGSAVSFNGKDKD---VLDESDWSDVDLLRSVKPFGWN---------YAVSKT 165 Query: 171 FAEKAAWEFLEENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLSPED 230 AEKA EF E+N ++ V + P + + V L S E L+ L ++ Sbjct: 166 LAEKAVLEFGEQN---------GIDVVTLILPFIVGRFVCPKLPDSIEKALVLV-LGKKE 215 Query: 231 KIPELFGGYIDVRDVAKAHLVAFQKRETIGQRLIVSEARFTMQDVLDILNEDFPVLKGNI 290 +I + V DVA+AH+ + G R S ++++ +L+ +P + + Sbjct: 216 QIGVTRFHMVHVDDVARAHIYLLE-NSVPGGRYNCSPFIVPIEEMSQLLSAKYPEYQ-IL 273 Query: 291 PVGKPGSGATHNTLGATLDNKKSKKLL--GFKFRNLKETIDDTASQILKFEGRI 342 V + GA L + +KKL+ GF F+ E + D A Q K +G + Sbjct: 274 TVDE-----LKEIKGARLPDLNTKKLVDAGFDFKYTIEDMFDDAIQCCKEKGYL 322 >1GY8-A nrPDB Length = 397 Score = 46.6 bits (109), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 71/306 (23%), Positives = 125/306 (40%), Gaps = 61/306 (19%) Query: 1 MSVFVSGANGFIAQHIVDLLLKE-DYKVI---------GSARSQEKAEN----LTEAFGN 46 M V V G G+I H V LL++ ++ V+ G + E EN L ++ G Sbjct: 3 MRVLVCGGAGYIGSHFVRALLRDTNHSVVIVDSLVGTHGKSDHVETRENVARKLQQSDGP 62 Query: 47 NP----KFSMEVVPDISKLDAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVN 102 P +++ V D+ D + VF +HG I V+H + + +S RD L N Sbjct: 63 KPPWADRYAALEVGDVRNEDFLNGVFTRHGP-IDAVVHMCA--FLAVGESVRDPLKYYDN 119 Query: 103 GVKGILHSIKKYAADSVERVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPV 162 V GIL ++ ++++ +SS AA+F S++ N E + + + P Sbjct: 120 NVVGILRLLQAMLLHKCDKIIFSSS-AAIF--GNPTMGSVSTNAEPID----INAKKSPE 172 Query: 163 NAYCGSKKFAEKAAWEFLEENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNS 222 + Y SK AE+ + + ++ + + G D D+ +H S L+ Sbjct: 173 SPYGESKLIAER----MIRDCAEAYGIKGICLRYFNACGAHE-DGDIGEHYQGSTHLIPI 227 Query: 223 LM-----HLSPE-----------DKIPELFGG------------YIDVRDVAKAHLVAFQ 254 ++ ++P+ DK +FG Y+ V D+A AH++A Sbjct: 228 ILGRVMSDIAPDQRLTIHEDASTDKRMPIFGTDYPTPDGTCVRDYVHVCDLASAHILALD 287 Query: 255 KRETIG 260 E +G Sbjct: 288 YVEKLG 293 >4LIS-A nrPDB Length = 371 Score = 40.8 bits (94), Expect = 8e-04, Method: Compositional matrix adjust. Identities = 55/192 (28%), Positives = 82/192 (42%), Gaps = 22/192 (11%) Query: 2 SVFVSGANGFIAQHIVDLLLKEDYKVIGS---ARSQEKAENLTEAF-GNNPKFSMEVVPD 57 SV V+G G+I LL+ YKV+ + S +A N E G +F+ D Sbjct: 5 SVLVTGGTGYIGSFTTLALLEAGYKVVVADNLYNSSAEALNRIELISGKKAEFAQL---D 61 Query: 58 ISKLDAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAAD 117 ++ AFD VF+ H DI V+H A+ E+ L VN V G + ++ Sbjct: 62 VTDEAAFDKVFEAH-PDIDSVIHFAALKAVG-ESGEKPLDYYHVN-VYGTICLLRSMVRH 118 Query: 118 SVERVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFA-EKAA 176 +V +V +SS A V+ A + E C P N Y G+ KFA E A Sbjct: 119 NVTNIVFSSS-ATVYGDATRFPDMIPIPEH---------CPLGPTNPY-GNTKFAIELAI 167 Query: 177 WEFLEENRDSVK 188 + + R++ K Sbjct: 168 TDVINAQRNNAK 179 >4WKG-A nrPDB Length = 660 Score = 40.0 bits (92), Expect = 0.002, Method: Compositional matrix adjust. Identities = 61/266 (22%), Positives = 106/266 (39%), Gaps = 57/266 (21%) Query: 3 VFVSGANGFIAQHIVDLLLKED-YKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKL 61 V + G NGFI H+ + LL+ED Y+V G + + F N+P F V DIS Sbjct: 318 VLILGVNGFIGNHLTERLLREDHYEVYG----LDIGSDAISRFLNHPHFHF-VEGDISIH 372 Query: 62 DAFDHVFQKHGKDIKIVL----------HTASPFCFDITDSERDLLIPAVNGVKGILHSI 111 + + H K +VL +T +P D E +L I Sbjct: 373 SEW---IEYHVKKCDVVLPLVAIATPIEYTRNPLRVFELDFEENL-------------RI 416 Query: 112 KKYAADSVERVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNA----YCG 167 +Y +R++ S+ + V+ M + F+E+ N PVN Y Sbjct: 417 IRYCVKYRKRIIFPST-SEVYGMCSDK----YFDEDHSNLIV------GPVNKPRWIYSV 465 Query: 168 SKKFAEKAAWEFLEENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLS 227 SK+ ++ W + E+ + T P GP++ + + + + +S + +++L Sbjct: 466 SKQLLDRVIWAYGEKE----GLQFTLFRPFNWMGPRLDNLNAAR-IGSSRAITQLILNLV 520 Query: 228 PEDKIPELFGG-----YIDVRDVAKA 248 I + GG + D+RD +A Sbjct: 521 EGSPIKLIDGGKQKRCFTDIRDGIEA 546 >5CDY-A nrPDB Length = 244 Score = 38.5 bits (88), Expect = 0.004, Method: Compositional matrix adjust. Identities = 23/80 (28%), Positives = 42/80 (52%) Query: 4 FVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKLDA 63 V+GA+ I + I +LL++ VIG+A S++ AE ++ G N K M V D + +D Sbjct: 9 LVTGASRGIGRAIAELLVERGACVIGTATSEKGAEAISAYLGENGKGLMLNVVDPTSIDT 68 Query: 64 FDHVFQKHGKDIKIVLHTAS 83 + ++ I+++ A Sbjct: 69 VLATIRAEFGEVDILVNNAG 88 >3RSH-A nrPDB Length = 251 Score = 35.4 bits (80), Expect = 0.037, Method: Compositional matrix adjust. Identities = 17/46 (36%), Positives = 29/46 (63%) Query: 4 FVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPK 49 V+GA+ I + I +LL + KVIG+A S+ A+ +++ G+N K Sbjct: 16 LVTGASRGIGKAIAELLAERGAKVIGTATSESGAQAISDYLGDNGK 61 >5JRE-A nrPDB Length = 219 Score = 34.7 bits (78), Expect = 0.065, Method: Compositional matrix adjust. Identities = 31/117 (26%), Positives = 59/117 (50%), Gaps = 9/117 (7%) Query: 94 RDLLIPAVNGVKGILHSIKKYAADSVERVVLTS--SYAAVFDMAKENDKSL-TFNEESWN 150 R ++P ++ +K +++ + V+R + S S + ++ M +E+ KS + EE N Sbjct: 32 RGSMLPNLDNLKEEYQKLEEKKQEIVDRSIRMSKLSKSLIYSMIREDYKSADKYKEELTN 91 Query: 151 PA--TWESCQSDPV---NAYCGSKKFAEKAA-WEFLEENRDSVKFELTAVNPVYVFG 201 A E + P+ N + G +++ E A + +++ENR K EL VY+FG Sbjct: 92 LAKTQIEELKKYPMFYSNGFIGLQEYVEALALYYYIKENRIPSKEELGVDTWVYLFG 148 >1Q7C-A nrPDB Length = 244 Score = 34.7 bits (78), Expect = 0.067, Method: Compositional matrix adjust. Identities = 21/80 (26%), Positives = 41/80 (51%) Query: 4 FVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKLDA 63 V+GA+ I + I + L KVIG+A S+ A+ +++ G N K M V D + +++ Sbjct: 9 LVTGASRGIGRAIAETLAARGAKVIGTATSENGAQAISDYLGANGKGLMLNVTDPASIES 68 Query: 64 FDHVFQKHGKDIKIVLHTAS 83 + ++ I+++ A Sbjct: 69 VLEKIRAEFGEVDILVNNAG 88 >6BI4-A nrPDB Length = 346 Score = 32.3 bits (72), Expect = 0.32, Method: Compositional matrix adjust. Identities = 53/248 (21%), Positives = 107/248 (43%), Gaps = 37/248 (14%) Query: 1 MSVFVSGANGFIAQHIVDLLLK--EDYKVIG-SARSQEKAENLTEAFGNNPKFSMEVVPD 57 M++ V+G GFI + V +L+ E YK+I A + N ++ ++P + V + Sbjct: 25 MNILVTGGAGFIGSNFVHYMLQSYETYKIINFDALTYSGNLNNVKSIQDHPNYYF-VKGE 83 Query: 58 ISKLDAFDHVFQKHGKDIKIVLHTASPFCFDIT-DSERDLLIPAVNGVKGILHSIKKYAA 116 I + +HV ++ +D++++++ A+ D + ++ V G +L +KKY Sbjct: 84 IQNGELLEHVIKE--RDVQVIVNFAAESHVDRSIENPIPFYDTNVIGTVTLLELVKKYPH 141 Query: 117 DSVERVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAA 176 + +V Y ++ K+ F EE+ P P + Y SK A+ A Sbjct: 142 IKLVQVSTDEVYGSL-------GKTGRFTEET--PLA-------PNSPYSSSKASADMIA 185 Query: 177 WEFLEENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLSPEDKIPELF 236 + + + V + N +GP + + +L+ ++ + E K L+ Sbjct: 186 LAYYKTYQLPVIVTRCSNN----YGPYQYPE----------KLIPLMVTNALEGKKLPLY 231 Query: 237 GGYIDVRD 244 G ++VRD Sbjct: 232 GDGLNVRD 239 >2J3K-A nrPDB Length = 345 Score = 32.3 bits (72), Expect = 0.33, Method: Compositional matrix adjust. Identities = 19/58 (32%), Positives = 32/58 (55%) Query: 2 SVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDIS 59 +V+VS A+G + Q + L V+GSA S+EK + L FG + F+ + D++ Sbjct: 158 TVYVSAASGAVGQLVGQLAKMMGCYVVGSAGSKEKVDLLKTKFGFDDAFNYKEESDLT 215 >1UDA-A nrPDB Length = 338 Score = 32.3 bits (72), Expect = 0.33, Method: Compositional matrix adjust. Identities = 70/296 (23%), Positives = 106/296 (35%), Gaps = 38/296 (12%) Query: 1 MSVFVSGANGFIAQHIVDLLLKEDYKVI---GSARSQEKAENLTEAFGN-NPKFSMEVVP 56 M V V+G +G+I H LL+ + VI S+ + E G +P F V Sbjct: 1 MRVLVTGGSGYIGSHTCVQLLQNGHDVIILDNLCNSKRSVLPVIERLGGKHPTF---VEG 57 Query: 57 DISKLDAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAA 116 DI + H I V+H A + +S + L N V G L I A Sbjct: 58 DIRNEALMTEILHDHA--IDTVIHFAG--LKAVGESVQKPLEYYDNNVNGTLRLISAMRA 113 Query: 117 DSVERVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAA 176 +V+ + +SS A V+ D ES+ T P + Y SK E+ Sbjct: 114 ANVKNFIFSSS-ATVY-----GDNPKIPYVESFPTGT-------PQSPYGKSKLMVEQIL 160 Query: 177 WEFLEENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLSPEDKIPELF 236 + + D L NPV +D + N + + + D + +F Sbjct: 161 TDLQKAQPDWSIALLRYFNPVGAHPSGDMGEDPQGIPNNLMPYIAQVA-VGRRDSL-AIF 218 Query: 237 GG------------YIDVRDVAKAHLVAFQKRETIGQRLIVSEARFTMQDVLDILN 280 G YI V D+A H+VA +K I + VLD++N Sbjct: 219 GNDYPTEDGTGVRDYIHVMDLADGHVVAMEKLANKPGVHIYNLGAGVGNSVLDVVN 274 >6BWL-A nrPDB Length = 328 Score = 32.0 bits (71), Expect = 0.43, Method: Compositional matrix adjust. Identities = 44/203 (21%), Positives = 82/203 (40%), Gaps = 24/203 (11%) Query: 1 MSVFVSGANGFIAQHIVDLLLKEDYKV-IGSARSQEKAENLTEAFGNNPKFSMEVVPDIS 59 M + V+G GFI + +V LL++ ++V I + N+TE F ++ + DI Sbjct: 1 MKILVTGGAGFIGRWVVKRLLQDKHEVWILDNLANSTTANITE-FAHDLNLKQCIQGDIK 59 Query: 60 KLDAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAADSV 119 +F+ + D + H A+ ++ DS D N G + +++ V Sbjct: 60 DKKLVAQLFENNSFD--LCYHLAAS--INVQDSIDDARATFENDTIGTFNLLEQCLNYDV 115 Query: 120 ERVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAAWEF 179 + V +++ V+D A N + ++ E P + Y GSK AE + Sbjct: 116 KMVFMST--CMVYDKAT-NIQGIS-----------ELDPIKPASPYAGSKIAAENMVLSY 161 Query: 180 LEENRDSVKFELTAVNPVYVFGP 202 + K + + P +GP Sbjct: 162 YY----AYKLPVVVIRPFNTYGP 180 >2C54-A nrPDB Length = 379 Score = 31.6 bits (70), Expect = 0.47, Method: Compositional matrix adjust. Identities = 17/42 (40%), Positives = 25/42 (59%), Gaps = 2/42 (4%) Query: 1 MSVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTE 42 + + ++GA GFIA HI L E + VI S +K E++TE Sbjct: 30 LKISITGAGGFIASHIARRLKHEGHYVIAS--DWKKNEHMTE 69 >3MYR-B nrPDB Length = 561 Score = 31.2 bits (69), Expect = 0.60, Method: Compositional matrix adjust. Identities = 17/56 (30%), Positives = 28/56 (50%), Gaps = 3/56 (5%) Query: 104 VKGILHSIKKYAADSVERVVLTSSYAAVFDMAKENDKS---LTFNEESWNPATWES 156 V + ++ + AA ++E +L + +D N KS TFNE W P++W S Sbjct: 420 VDALYSTLGRTAARALESKILVDAMQGWYDGLIANVKSGDTKTFNETLWEPSSWPS 475 >4WOK-A nrPDB Length = 336 Score = 31.2 bits (69), Expect = 0.66, Method: Compositional matrix adjust. Identities = 61/306 (19%), Positives = 114/306 (37%), Gaps = 47/306 (15%) Query: 2 SVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKL 61 +V V G GFI H LL + Y + +NL+ + ++ V DI Sbjct: 13 NVLVVGGAGFIGSHTAKLLAGQGYAPV-------VYDNLSTGHQSAVRWGDFVEGDILDQ 65 Query: 62 DAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAADSVER 121 +K+ + ++ AS + + + V G + +L + + + Sbjct: 66 ARLVETMEKYAP-VAVIHFAASAYVGESVEDPAKYYRNNVGGTQSLLDACR---LTRTQN 121 Query: 122 VVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAAWEFLE 181 V+ +SS A T+ S P E +P+N Y +K AE ++ Sbjct: 122 VIFSSSCA-------------TYGVPSRLP-IGEGEAQNPINPYGRTKLIAEHMLADY-- 165 Query: 182 ENRDSVKFELTAVNPVYVFGPQMFDKDVK---KHLNTSCELVNSLMHLSPEDKIPELFGG 238 +V + L V Y F D D + KH + + ++M + + E++G Sbjct: 166 ----AVAYGLRYVALRY-FNASGADIDGELGEKHDPETHLIPRAMMAAAGRLDVLEVYGD 220 Query: 239 ------------YIDVRDVAKAHLVAFQKRETIGQRLIVSEARFTMQDVLDILNEDFPVL 286 YI V D+A+AH++A + + G L V+ + +I+ + Sbjct: 221 DYETPDGTCIRDYIHVTDLARAHVLAVEHLKEAGGNLAVNLGTGRGTSIREIVQSIGRLT 280 Query: 287 KGNIPV 292 ++PV Sbjct: 281 GRSVPV 286 >1I3M-A nrPDB Length = 348 Score = 30.4 bits (67), Expect = 1.3, Method: Compositional matrix adjust. Identities = 65/289 (22%), Positives = 104/289 (35%), Gaps = 55/289 (19%) Query: 3 VFVSGANGFIAQHIVDLLLKEDYKVI----------GSARSQEKAENLTEAFGNNPKFSM 52 V V+G G+I H V LL+ Y + G E + E G + +F Sbjct: 5 VLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRSVEFEE 64 Query: 53 EVVPDISKLDAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIK 112 DI A +F+K+ V+H A G+K + S++ Sbjct: 65 M---DILDQGALQRLFKKY--SFMAVIHFA--------------------GLKAMGESVQ 99 Query: 113 KYAADSVERVVLTSSYAAVFDMAKENDKSLTFNEES---WNPATWESCQSDPV----NAY 165 K RV LT + + M K+L F+ + NP ++ P N Y Sbjct: 100 K--PLDYYRVNLTGTIQLLEIMKAHGVKNLVFSSSATVYGNPQYLPLDEAHPTGGCTNPY 157 Query: 166 CGSKKFAEKAAWEFLEENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSL-- 223 SK F E+ + + ++ L NP +D + N V+ + Sbjct: 158 GKSKFFIEEMIRDLCQADKTWNVVLLRYFNPTGAHASGCIGEDPQGIPNNLMPYVSQVAI 217 Query: 224 -----MHLSPEDKIPELFGG---YIDVRDVAKAHLVAFQK-RETIGQRL 263 +++ D E G YI V D+AK H+ A +K +E G R+ Sbjct: 218 GRREALNVFGNDYDTEDGTGVRDYIHVVDLAKGHIAALRKLKEQCGCRI 266 >2Q1W-A nrPDB Length = 333 Score = 29.6 bits (65), Expect = 2.0, Method: Compositional matrix adjust. Identities = 13/27 (48%), Positives = 18/27 (66%) Query: 3 VFVSGANGFIAQHIVDLLLKEDYKVIG 29 VF++G G I HI +LLL+ KV+G Sbjct: 24 VFITGICGQIGSHIAELLLERGDKVVG 50 >1E5Q-A nrPDB Length = 450 Score = 29.3 bits (64), Expect = 2.5, Method: Compositional matrix adjust. Identities = 22/80 (27%), Positives = 39/80 (48%), Gaps = 5/80 (6%) Query: 2 SVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKL 61 SV + G +GF+ + +D+L KV + R+ E A+ L+ ++ S++V D Sbjct: 5 SVLMLG-SGFVTRPTLDVLTDSGIKVTVACRTLESAKKLSAGVQHSTPISLDVNDDA--- 60 Query: 62 DAFDHVFQKHGKDIKIVLHT 81 A D KH I ++ +T Sbjct: 61 -ALDAEVAKHDLVISLIPYT 79 >5XWI-A nrPDB Length = 567 Score = 28.9 bits (63), Expect = 2.9, Method: Compositional matrix adjust. Identities = 23/73 (31%), Positives = 34/73 (46%), Gaps = 5/73 (6%) Query: 223 LMHLSPEDKIPELFG--GYIDVRDVAKAHLVAFQKRETIGQRLIVSEARFTMQDVLDILN 280 +M + D++ L G GY+ + VA LV Q + QRL F + ++ Sbjct: 177 MMGGATADQVWWLGGPQGYVSYKGVAPTPLVT-QVNQAFAQRLAQPNPGFELP--AQCVS 233 Query: 281 EDFPVLKGNIPVG 293 +DFPV GN VG Sbjct: 234 KDFPVQAGNRTVG 246 >6FKI-F nrPDB Length = 498 Score = 28.5 bits (62), Expect = 4.6, Method: Compositional matrix adjust. Identities = 24/107 (22%), Positives = 51/107 (47%), Gaps = 9/107 (8%) Query: 210 KKHLNTSCELVNSLMHLS-PEDKIPELFGGYI-DVRDVAKAHL-VAFQKRETIGQ---RL 263 KK+L +++ ++ ++ P K+P ++ I RD A + V + ++ +G R Sbjct: 17 KKNLGRIAQIIGPVLDVAFPPGKMPNIYNALIVKGRDTAGQPMNVTCEVQQLLGNNRVRA 76 Query: 264 IVSEARFTMQDVLDILNEDFPVLKGNIPVGKPGSGATHNTLGATLDN 310 + A + +++++ P+ ++PVG G N LG +DN Sbjct: 77 VAMSATDGLTRGMEVIDTGAPL---SVPVGGATLGRIFNVLGEPVDN 120 >4R7O-A nrPDB Length = 292 Score = 28.5 bits (62), Expect = 4.6, Method: Compositional matrix adjust. Identities = 15/67 (22%), Positives = 35/67 (52%), Gaps = 4/67 (5%) Query: 60 KLDAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHS----IKKYA 115 K+ + +FQK+G+ +K + T SP + + + L+ N + + S I+ ++ Sbjct: 110 KVPTLEEIFQKYGRSMKYYIETKSPDVYPGMEEKLLALLEKYNLIGQNMSSSRVMIQSFS 169 Query: 116 ADSVERV 122 DS++++ Sbjct: 170 KDSLKKI 176 >3F9I-A nrPDB Length = 249 Score = 28.1 bits (61), Expect = 5.8, Method: Compositional matrix adjust. Identities = 18/51 (35%), Positives = 29/51 (56%), Gaps = 2/51 (3%) Query: 4 FVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEV 54 ++GA+ I I LL K KVI S ++EK ++L A +N +++EV Sbjct: 18 LITGASSGIGSAIARLLHKLGSKVIISGSNEEKLKSLGNALKDN--YTIEV 66 >2AXQ-A nrPDB Length = 467 Score = 28.1 bits (61), Expect = 6.4, Method: Compositional matrix adjust. Identities = 20/78 (25%), Positives = 36/78 (46%), Gaps = 6/78 (7%) Query: 8 ANGFIAQHIVDLL-LKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKLDAFDH 66 +GF+AQ ++D L +D V + R+ A+ L + P S + D++ A D Sbjct: 30 GSGFVAQPVIDTLAANDDINVTVACRTLANAQALAK-----PSGSKAISLDVTDDSALDK 84 Query: 67 VFQKHGKDIKIVLHTASP 84 V + I ++ +T P Sbjct: 85 VLADNDVVISLIPYTFHP 102 >3ENK-A nrPDB Length = 341 Score = 27.7 bits (60), Expect = 8.3, Method: Compositional matrix adjust. Identities = 21/86 (24%), Positives = 34/86 (39%), Gaps = 9/86 (10%) Query: 2 SVFVSGANGFIAQHIVDLLLKEDYKVIGS----ARSQEKAENLTEAFGNNPKFSMEVVPD 57 ++ V+G G+I H LL Y V+ + +E + + G P F D Sbjct: 7 TILVTGGAGYIGSHTAVELLAHGYDVVIADNLVNSKREAIARIEKITGKTPAFHET---D 63 Query: 58 ISKLDAFDHVFQKHGKDIKIVLHTAS 83 +S A +F H I +H A+ Sbjct: 64 VSDERALARIFDAH--PITAAIHFAA 87 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 4PVC-A nrPDB 448 e-126 5B6K-A nrPDB 403 e-113 5YWN-A nrPDB 357 3e-99 4R1T-A nrPDB 317 3e-87 2NNL-D nrPDB 314 3e-86 4R1U-A nrPDB 312 1e-85 2P4H-X nrPDB 296 1e-80 4QUK-A nrPDB 294 5e-80 3HFS-A nrPDB 287 6e-78 1ZZE-A nrPDB 274 4e-74 1GY8-A nrPDB 202 2e-52 4WKG-A nrPDB 169 2e-42 4LIS-A nrPDB 156 1e-38 Sequences not found previously or not previously below threshold: 1UDA-A nrPDB 121 4e-28 1Z45-A nrPDB 116 1e-26 2C20-A nrPDB 105 2e-23 3ENK-A nrPDB 105 2e-23 1I3M-A nrPDB 104 4e-23 4WOK-A nrPDB 103 1e-22 1BXK-A nrPDB 84 7e-17 4EJ0-A nrPDB 81 7e-16 2Q1W-A nrPDB 80 2e-15 6BWL-A nrPDB 77 1e-14 2PK3-A nrPDB 73 2e-13 1R66-A nrPDB 73 3e-13 2Q1T-A nrPDB 71 6e-13 1EQ2-A nrPDB 66 2e-11 1KEU-A nrPDB 66 2e-11 1WVG-A nrPDB 65 5e-11 2X86-A nrPDB 64 9e-11 1OC2-A nrPDB 63 2e-10 2HUN-A nrPDB 62 3e-10 3SXP-A nrPDB 59 4e-09 2C54-A nrPDB 58 5e-09 3M2P-A nrPDB 58 6e-09 6BI4-A nrPDB 58 7e-09 1RKX-A nrPDB 57 1e-08 1DB3-A nrPDB 55 4e-08 1ORR-A nrPDB 54 8e-08 2PZM-A nrPDB 53 2e-07 4G5H-A nrPDB 53 2e-07 2GN9-A nrPDB 53 2e-07 4BKP-A nrPDB 53 3e-07 3RUE-A nrPDB 52 3e-07 5UZH-A nrPDB 51 8e-07 6AQY-A nrPDB 50 2e-06 5U9C-A nrPDB 50 2e-06 4J2O-A nrPDB 49 4e-06 3WMX-A nrPDB 48 4e-06 1RPN-A nrPDB 48 8e-06 2Z95-A nrPDB 47 1e-05 1N7G-A nrPDB 47 1e-05 6GCS-E nrPDB 47 1e-05 6GPK-A nrPDB 46 3e-05 5OVL-A nrPDB 45 6e-05 5OVJ-A nrPDB 45 6e-05 3SLK-A nrPDB 44 1e-04 1UZM-A nrPDB 43 2e-04 3RFT-A nrPDB 42 4e-04 4WPG-A nrPDB 42 4e-04 1BDB-A nrPDB 42 4e-04 4B4O-A nrPDB 41 8e-04 3PPI-A nrPDB 41 8e-04 6CI9-A nrPDB 40 0.001 5CDY-A nrPDB 39 0.002 2NM0-A nrPDB 39 0.002 1Q7C-A nrPDB 39 0.002 3RSH-A nrPDB 39 0.003 3OSU-A nrPDB 38 0.004 2DKN-A nrPDB 37 0.011 5F5N-A nrPDB 37 0.012 5ILO-A nrPDB 37 0.013 1HE4-A nrPDB 36 0.018 5ITV-A nrPDB 36 0.024 3LYL-A nrPDB 36 0.025 1QYC-A nrPDB 36 0.025 2GGS-A nrPDB 36 0.031 3UN1-A nrPDB 35 0.041 5LCX-A nrPDB 35 0.042 5GXF-A nrPDB 35 0.048 4IIV-A nrPDB 35 0.049 1CYD-A nrPDB 35 0.054 1GFS-A nrPDB 35 0.055 2J3K-A nrPDB 35 0.057 4IIN-A nrPDB 34 0.062 3F9I-A nrPDB 34 0.072 1AE1-A nrPDB 34 0.11 4CQM-B nrPDB 34 0.11 2Q4B-A nrPDB 34 0.13 4KTT-E nrPDB 33 0.16 2QYS-A nrPDB 33 0.16 3SC6-A nrPDB 33 0.18 1DXY-A nrPDB 33 0.20 2AE2-A nrPDB 33 0.20 1V3V-A nrPDB 33 0.23 3DWF-A nrPDB 33 0.24 1HXH-A nrPDB 33 0.24 1VL0-A nrPDB 33 0.28 1O89-A nrPDB 33 0.28 6G2J-P nrPDB 33 0.29 3D3W-A nrPDB 32 0.32 2B4Q-A nrPDB 32 0.37 5TQV-A nrPDB 32 0.37 2YV2-A nrPDB 32 0.45 2Y05-A nrPDB 32 0.47 2X9N-A nrPDB 31 0.57 3GRP-A nrPDB 31 0.59 4BO1-A nrPDB 31 0.69 1QYD-A nrPDB 31 0.84 5TZ8-A nrPDB 31 0.87 5WQO-A nrPDB 31 0.92 2VCE-A nrPDB 31 0.92 4Q2R-A nrPDB 31 0.94 1P33-A nrPDB 31 0.96 2EXX-A nrPDB 31 1.1 2BKA-A nrPDB 30 1.3 5PGZ-A nrPDB 30 1.4 6DKT-A nrPDB 30 1.4 4IQF-A nrPDB 30 1.4 1H5Q-A nrPDB 30 1.4 5B1Y-A nrPDB 30 1.6 1VIM-A nrPDB 30 1.6 3PVZ-A nrPDB 29 1.9 1YXM-A nrPDB 29 2.0 3V2G-A nrPDB 29 2.2 4AXH-A nrPDB 29 2.3 2WEK-A nrPDB 29 2.3 2TMD-A nrPDB 29 2.4 5ZG8-A nrPDB 29 3.6 3PVW-A nrPDB 28 4.5 4HP8-A nrPDB 28 9.1 >4PVC-A nrPDB Length = 342 Score = 448 bits (1151), Expect = e-126, Method: Composition-based stats. Identities = 342/342 (100%), Positives = 342/342 (100%) Query: 1 MSVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISK 60 MSVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISK Sbjct: 1 MSVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISK 60 Query: 61 LDAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAADSVE 120 LDAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAADSVE Sbjct: 61 LDAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAADSVE 120 Query: 121 RVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAAWEFL 180 RVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAAWEFL Sbjct: 121 RVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAAWEFL 180 Query: 181 EENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLSPEDKIPELFGGYI 240 EENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLSPEDKIPELFGGYI Sbjct: 181 EENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLSPEDKIPELFGGYI 240 Query: 241 DVRDVAKAHLVAFQKRETIGQRLIVSEARFTMQDVLDILNEDFPVLKGNIPVGKPGSGAT 300 DVRDVAKAHLVAFQKRETIGQRLIVSEARFTMQDVLDILNEDFPVLKGNIPVGKPGSGAT Sbjct: 241 DVRDVAKAHLVAFQKRETIGQRLIVSEARFTMQDVLDILNEDFPVLKGNIPVGKPGSGAT 300 Query: 301 HNTLGATLDNKKSKKLLGFKFRNLKETIDDTASQILKFEGRI 342 HNTLGATLDNKKSKKLLGFKFRNLKETIDDTASQILKFEGRI Sbjct: 301 HNTLGATLDNKKSKKLLGFKFRNLKETIDDTASQILKFEGRI 342 >5B6K-A nrPDB Length = 366 Score = 403 bits (1034), Expect = e-113, Method: Composition-based stats. Identities = 212/341 (62%), Positives = 256/341 (75%), Gaps = 4/341 (1%) Query: 2 SVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKL 61 +VFVSGA GFIAQH+V LL ++YKVIGS RS EK ++L F+ E+V DIS Sbjct: 23 TVFVSGATGFIAQHVVRQLLDQNYKVIGSVRSAEKGDHLKNVIFKGGDFNYEIVKDISDP 82 Query: 62 DAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAADSVER 121 AFDHVF+KHGKDIK+VLHTASPF F+ TD E+DLLIPAVNG KGIL SIKKYAA +VER Sbjct: 83 TAFDHVFEKHGKDIKVVLHTASPFHFNTTDIEKDLLIPAVNGTKGILESIKKYAAQTVER 142 Query: 122 VVLTSSYAA---VFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAAWE 178 VV+TSS+AA DM D S T EESWN TWESCQSDP+ YCGSKKFAEKAAW+ Sbjct: 143 VVVTSSFAANTSTVDMFYAKDSSKTITEESWNQDTWESCQSDPIRGYCGSKKFAEKAAWD 202 Query: 179 FLEENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLSPEDKIPELFGG 238 F N+DSVKF+L+ +NPVYVFGPQ + + KK LNTS E++NSL+HL +D +PE GG Sbjct: 203 FYNANKDSVKFKLSIINPVYVFGPQNYVEPGKKILNTSSEVINSLVHLKKDDPLPEFAGG 262 Query: 239 YIDVRDVAKAHLVAFQKRETIGQRLIVSEARFTMQDVLDILNEDFPVLKGNIPVGKPGSG 298 +IDVRDVAKAH++AFQK E I QRL++ FT Q +LDI+NE FP LKG IP GKPG+G Sbjct: 263 HIDVRDVAKAHILAFQKDELIEQRLMLHAGLFTTQTLLDIINEQFPELKGKIPAGKPGTG 322 Query: 299 ATHNTLGATLDNKKSKKLLGFKFRNLKETIDDTASQILKFE 339 + L +DN K+KKLLGF+F +LK+ + DT SQIL+ E Sbjct: 323 NPDDAL-TPVDNSKTKKLLGFEFIDLKKDLYDTISQILEAE 362 >5YWN-A nrPDB Length = 334 Score = 357 bits (916), Expect = 3e-99, Method: Composition-based stats. Identities = 153/339 (45%), Positives = 228/339 (67%), Gaps = 8/339 (2%) Query: 2 SVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKL 61 SVFVSGA G++AQ I+ L+L + YKV+GS RS+EK NL + +G++ FS EVV + + Sbjct: 4 SVFVSGATGYLAQQIIALVLSKGYKVVGSVRSEEKGANLKKLYGDD--FSYEVVKVLEQK 61 Query: 62 DAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAADSVER 121 AFD +KH ++ I LHTASP F++ D+E+++LIPA+NG K +L SIK A + R Sbjct: 62 GAFDEALKKH-PEVTIFLHTASPVTFEVEDTEKEILIPAINGTKYVLQSIKD-VAPQITR 119 Query: 122 VVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAAWEFLE 181 VV TSS A+ + + +E SW+ ++E ++ V AY GSK+FAE+AAWEF+E Sbjct: 120 VVYTSSVVAMSVPEELGSPDVVLSEASWSSLSYEQSKTHGVLAYFGSKQFAERAAWEFVE 179 Query: 182 ENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLSPEDKIPELFGGYID 241 + + + F L+ VNPVY+FGPQ D++VK LN S E+VNS++ L+ +D +P G +ID Sbjct: 180 QEKPN--FALSTVNPVYIFGPQAKDEEVKGTLNHSAEMVNSVLKLNKDDDVPATTGTFID 237 Query: 242 VRDVAKAHLVAFQKRETIGQRLIVSEARFTMQDVLDILNEDFPVLKGNIPVGKPGSGATH 301 VRDVAKAHL AF+K E G+RL++S RF Q +LD++ ++FP L +PVGKP S Sbjct: 238 VRDVAKAHLAAFEKDEAKGERLLLSNTRFNGQTLLDVVRKNFPQLADKLPVGKPHSD--D 295 Query: 302 NTLGATLDNKKSKKLLGFKFRNLKETIDDTASQILKFEG 340 + ++KK+KK+LGF++ + + ++ D+ Q+LK +G Sbjct: 296 FSAFKEWNDKKTKKILGFEYFDFETSVVDSIKQVLKVQG 334 >4R1T-A nrPDB Length = 337 Score = 317 bits (813), Expect = 3e-87, Method: Composition-based stats. Identities = 100/343 (29%), Positives = 165/343 (48%), Gaps = 36/343 (10%) Query: 3 VFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAEN--LTEAFGNNPKFSMEVVPDISK 60 V V+GA GFIA +V +LL++ Y V G+ R+ + +N L E G + ++ D+ Sbjct: 13 VCVTGAGGFIASWLVKILLEKGYTVRGTVRNPDDPKNGHLRELEGAKERLTL-CKADLLD 71 Query: 61 LDAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAADSVE 120 + V HTASP +TD ++ PAV G K ++++ A +V Sbjct: 72 YQSLREAI----NGCDGVFHTASP----VTDDPEQMVEPAVIGTKNVINA---AAEANVR 120 Query: 121 RVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAAWEFL 180 RVV TSS AV+ M D +E W+ + C++ N YC K AE+AAWE Sbjct: 121 RVVFTSSIGAVY-MDPNRDPETVVDETCWSDPDF--CKNTK-NWYCYGKMVAEQAAWEEA 176 Query: 181 EENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLSPEDKI-PELFGGY 239 +E +L +NPV V GP + + +N S +++ L +L+ K Y Sbjct: 177 KEK----GVDLVVINPVLVQGPLL-----QTTVNAS--VLHILKYLTGSAKTYANSVQAY 225 Query: 240 IDVRDVAKAHLVAFQKRETIGQRLIVSEARFTMQDVLDILNEDFPVLKGNIPVGKPGSGA 299 +DV+DVA AH++ ++ E G R + +E+ DV++IL++ FP P+ S Sbjct: 226 VDVKDVALAHILLYETPEASG-RYLCAESVLHRGDVVEILSKFFPE----YPIPTKCSDV 280 Query: 300 THNTLGATLDNKKSKKLLGFKFRNLKETIDDTASQILKFEGRI 342 T + + + K LG +F +K+ + +T L+ +G + Sbjct: 281 TKPRVKPYKFSNQKLKDLGLEFTPVKQCLYETVKS-LQEKGHL 322 >2NNL-D nrPDB Length = 337 Score = 314 bits (805), Expect = 3e-86, Method: Composition-based stats. Identities = 82/344 (23%), Positives = 142/344 (41%), Gaps = 28/344 (8%) Query: 2 SVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVV---PDI 58 +V V+GA+GFI +V LL+ Y V + R + + + PK + D+ Sbjct: 7 TVCVTGASGFIGSWLVMRLLERGYTVRATVRDPTNVKKVKHLL-DLPKAETHLTLWKADL 65 Query: 59 SKLDAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAADS 118 + +FD K V H A+P F+ D E +++ P + G+ GI+ S AA + Sbjct: 66 ADEGSFDEAI----KGCTGVFHVATPMDFESKDPENEVIKPTIEGMLGIMKSCA--AAKT 119 Query: 119 VERVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAAWE 178 V R+V TSS V + + ++E W+ + + Y SK AE+AAW+ Sbjct: 120 VRRLVFTSSAGTV---NIQEHQLPVYDESCWSDMEFCRAKKMTAWMYFVSKTLAEQAAWK 176 Query: 179 FLEENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLSPEDKIPELFGG 238 + +EN + + P V GP + + + + H S + G Sbjct: 177 YAKENN----IDFITIIPTLVVGPFIMSSMPPSLITALSPITGNEAHYSIIRQ-----GQ 227 Query: 239 YIDVRDVAKAHLVAFQKRETIGQRLIVSEARFTMQDVLDILNEDFPVLKGNIPVGKPGSG 298 ++ + D+ AH+ F+ + G R I S + D+ +L E +P + G Sbjct: 228 FVHLDDLCNAHIYLFENPKAEG-RYICSSHDCIILDLAKMLREKYPEYN----IPTEFKG 282 Query: 299 ATHNTLGATLDNKKSKKLLGFKFRNLKETIDDTASQILKFEGRI 342 N +KK LGF+F+ E + A + +G + Sbjct: 283 VDENLKSVCFSSKKLT-DLGFEFKYSLEDMFTGAVDTCRAKGLL 325 >4R1U-A nrPDB Length = 349 Score = 312 bits (799), Expect = 1e-85, Method: Composition-based stats. Identities = 101/344 (29%), Positives = 159/344 (46%), Gaps = 36/344 (10%) Query: 2 SVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAEN--LTEAFGNNPKFSMEVVPDIS 59 +V V+GA GFIA +V LLL+ Y V G+ R+ E +N L E G + ++ V D+ Sbjct: 29 TVCVTGAGGFIASWLVKLLLERGYTVRGTVRNPEDPKNGHLKELEGARERLTLHKV-DLL 87 Query: 60 KLDAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAADSV 119 L + V V HTASP +TD+ ++L PAVNG K + I A V Sbjct: 88 DLQSIQSVVH----GCHGVFHTASP----VTDNPDEMLEPAVNGTKNV---IIASAEAKV 136 Query: 120 ERVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAAWEF 179 RVV TSS V+ M + + +E W+ E C++ N YC K AE++AW+ Sbjct: 137 RRVVFTSSIGTVY-MDPNTSRDVVVDESYWSDL--EHCKNTK-NWYCYGKTVAEQSAWDI 192 Query: 180 LEENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLSPEDKI-PELFGG 238 +EN+ + V GP + + +N S ++ L +L+ K Sbjct: 193 AKENQVDLVVVNPV----VVLGPLL-----QPTINAST--IHILKYLNGAAKTYVNATQS 241 Query: 239 YIDVRDVAKAHLVAFQKRETIGQRLIVSEARFTMQDVLDILNEDFPVLKGNIPVGKPGSG 298 Y+ V+DVA AHL+ ++ G R I E +V++IL + FP P+ S Sbjct: 242 YVHVKDVALAHLLVYETNSASG-RYICCETALHRGEVVEILAKYFPE----YPLPTKCSD 296 Query: 299 ATHNTLGATLDNKKSKKLLGFKFRNLKETIDDTASQILKFEGRI 342 + + + + K LG +F +K+ + DT L+ +G + Sbjct: 297 EKNPRVKPYKFSNQKLKDLGLEFTPVKQCLYDTVRS-LQEKGHL 339 >2P4H-X nrPDB Length = 322 Score = 296 bits (756), Expect = 1e-80, Method: Composition-based stats. Identities = 88/346 (25%), Positives = 146/346 (42%), Gaps = 31/346 (8%) Query: 2 SVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEV---VPDI 58 V V+G GF+ I+ LL+ Y V + R+ + + N P S ++ D+ Sbjct: 3 RVCVTGGTGFLGSWIIKSLLENGYSVNTTIRADPERKRDVSFLTNLPGASEKLHFFNADL 62 Query: 59 SKLDAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAADS 118 S D+F + + HTASP F +++ E + V+G GIL + + + Sbjct: 63 SNPDSFAAAIE----GCVGIFHTASPIDFAVSEPEEIVTKRTVDGALGILKACVN--SKT 116 Query: 119 VERVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAAWE 178 V+R + TSS +AV K+ D +E W+ Y SK AEKA E Sbjct: 117 VKRFIYTSSGSAVSFNGKDKD---VLDESDWSDVDLLRSVKPFGWNYAVSKTLAEKAVLE 173 Query: 179 FLEENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLSPEDKIPELFGG 238 F E+N ++ V + P + + V L S E L+ L +++I Sbjct: 174 FGEQN---------GIDVVTLILPFIVGRFVCPKLPDSIEKALVLV-LGKKEQIGVTRFH 223 Query: 239 YIDVRDVAKAHLVAFQKRETIGQRLIVSEARFTMQDVLDILNEDFPVLKGNIPVGKPGSG 298 + V DVA+AH+ + G R S ++++ +L+ +P + + V Sbjct: 224 MVHVDDVARAHIYLLE-NSVPGGRYNCSPFIVPIEEMSQLLSAKYPEYQ-ILTV-----D 276 Query: 299 ATHNTLGATLDNKKSKKLL--GFKFRNLKETIDDTASQILKFEGRI 342 GA L + +KKL+ GF F+ E + D A Q K +G + Sbjct: 277 ELKEIKGARLPDLNTKKLVDAGFDFKYTIEDMFDDAIQCCKEKGYL 322 >4QUK-A nrPDB Length = 319 Score = 294 bits (751), Expect = 5e-80, Method: Composition-based stats. Identities = 98/340 (28%), Positives = 169/340 (49%), Gaps = 30/340 (8%) Query: 3 VFVSGANGFIAQHIVDLLLKEDYKVIGSAR---SQEKAENLTEAFGNNPKFSMEVVPDIS 59 V V+GA+G+IA +V LLL Y V + R +K ++L + G + + ++ Sbjct: 3 VCVTGASGYIASWLVRLLLHRGYTVKATVRDPNDPKKVDHLVKLDGAKERLQL-FKANLL 61 Query: 60 KLDAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAADSV 119 + AFD V Q V HTASPF D+ D + +L+ PA+ G +L+S K + S+ Sbjct: 62 EEGAFDSVVQ----GCHGVFHTASPFYHDVKDPQAELIDPALKGTLNVLNSCAK--SPSL 115 Query: 120 ERVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAAWEF 179 +RVVLTSS AAV K + +E + A + C + Y S AE+AAW+F Sbjct: 116 KRVVLTSSIAAVAYNGKPRTPDVVVDETWFTDADF--CAKSNL-WYVVSATLAEEAAWKF 172 Query: 180 LEENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLSPEDKIPELFGGY 239 ++EN ++ +NP V GP + + LNTS + +L++ + P G+ Sbjct: 173 VKENN----IDMVTINPAMVIGPLL-----QPVLNTSAAAILNLINGA--QTFPNASFGW 221 Query: 240 IDVRDVAKAHLVAFQKRETIGQRLIVSEARFTMQDVLDILNEDFPVLKGNIPVGKPGSGA 299 ++V+DVA AH++A++ G+ +V E +V+ IL E +P L+ + + + Sbjct: 222 VNVKDVANAHILAYENASASGRHCLV-ERVAHYSEVVRILRELYPSLQ----LPEKCAD- 275 Query: 300 THNTLGATLDNKKSKKLLGFKFRNLKETIDDTASQILKFE 339 + +K+ K LG ++ L+ +I +T + + + Sbjct: 276 DKPYVPIYQVSKEKAKSLGLEYTPLEVSIKETVESLKEKK 315 >3HFS-A nrPDB Length = 338 Score = 287 bits (733), Expect = 6e-78, Method: Composition-based stats. Identities = 95/349 (27%), Positives = 156/349 (44%), Gaps = 31/349 (8%) Query: 2 SVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQE---KAENLTEA--FGNNPKFSMEVVP 56 + V G GF+A +V LLL++ Y V + R + K +L E G+ F ++ Sbjct: 11 TACVVGGTGFVASLLVKLLLQKGYAVNTTVRDPDNQKKVSHLLELQELGDLKIFRADLTD 70 Query: 57 DISKLDAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAA 116 ++S F+ V H A+P F D E D++ PA+ GV ++ + + A Sbjct: 71 ELS--------FEAPIAGCDFVFHVATPVHFASEDPENDMIKPAIQGVVNVMKACTR--A 120 Query: 117 DSVERVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAA 176 SV+RV+LTSS AAV + + + L +E++W + + P Y SK AEKAA Sbjct: 121 KSVKRVILTSSAAAV-TINQLDGTGLVVDEKNWTDIEFLTSAKPPTWGYPASKTLAEKAA 179 Query: 177 WEFLEENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLSPEDKIPELF 236 W+F EEN +L V P + G + DV + + L+ L K ++ Sbjct: 180 WKFAEENN----IDLITVIPTLMAGSSL-TSDVPSSIGLAMSLITGNEFLINGMKGMQML 234 Query: 237 GGYI---DVRDVAKAHLVAFQKRETIGQRLIVSEARFTMQDVLDILNEDFPVLKGNIPVG 293 G + V DV +AH+ +K G R I A ++ ++ L++ +P K +P Sbjct: 235 SGSVSIAHVEDVCRAHIFVAEKESASG-RYICCAANTSVPELAKFLSKRYPQYK--VPTD 291 Query: 294 KPGSGATHNTLGATLDNKKSKKLLGFKFRNLKETIDDTASQILKFEGRI 342 G + ++K K GF F+ E I D + + K +G + Sbjct: 292 F---GDFPPKSKLIISSEKLVKE-GFSFKYGIEEIYDESVEYFKAKGLL 336 >1ZZE-A nrPDB Length = 342 Score = 274 bits (700), Expect = 4e-74, Method: Composition-based stats. Identities = 96/341 (28%), Positives = 151/341 (44%), Gaps = 24/341 (7%) Query: 3 VFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNN--PKFSMEVVPDISK 60 V V+GANGF+A H+V+ LL+ YKV G+ARS K NL + + +F VV D+ K Sbjct: 14 VLVTGANGFVASHVVEQLLEHGYKVRGTARSASKLANLQKRWDAKYPGRFETAVVEDMLK 73 Query: 61 LDAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAADSVE 120 A+D V K V H AS F ++ +++ PA+ G L + A SV+ Sbjct: 74 QGAYDEVI----KGAAGVAHIASVVSF--SNKYDEVVTPAIGGTLNALRA--AAATPSVK 125 Query: 121 RVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPV-------NAYCGSKKFAE 173 R VLTSS + + K N + + +E+SWN + + ++ P Y SK AE Sbjct: 126 RFVLTSSTVSAL-IPKPNVEGIYLDEKSWNLESIDKAKTLPESDPQKSLWVYAASKTEAE 184 Query: 174 KAAWEFLEENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLSPEDKIP 233 AAW+F++EN+ F L AV P Y G +FD + + + + +SP + Sbjct: 185 LAAWKFMDENKP--HFTLNAVLPNYTIG-TIFDPETQSGSTSGWMMSLFNGEVSPALALM 241 Query: 234 ELFGGYIDVRDVAKAHLVAFQKRETIGQRLIVSEARFTMQDVLDILNEDFPVLKGNIPVG 293 Y+ D+ HL + +R+ + F VL + +P P Sbjct: 242 PP-QYYVSAVDIGLLHLGCLVLPQIERRRVYGTAGTFDWNTVLATFRKLYP--SKTFPAD 298 Query: 294 KPGSGATHNTLGATLDNKKSKKLLGFKFRNLKETIDDTASQ 334 P G + + K L +R+++E+I D Sbjct: 299 FPDQGQDLSKFDTAPSLEILKSLGRPGWRSIEESIKDLVGS 339 >1GY8-A nrPDB Length = 397 Score = 202 bits (513), Expect = 2e-52, Method: Composition-based stats. Identities = 82/392 (20%), Positives = 158/392 (40%), Gaps = 80/392 (20%) Query: 1 MSVFVSGANGFIAQHIVDLLLKE-DYKVI---------GSARSQEKAEN----LTEAFGN 46 M V V G G+I H V LL++ ++ V+ G + E EN L ++ G Sbjct: 3 MRVLVCGGAGYIGSHFVRALLRDTNHSVVIVDSLVGTHGKSDHVETRENVARKLQQSDGP 62 Query: 47 NP----KFSMEVVPDISKLDAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVN 102 P +++ V D+ D + VF +HG I V+H + + +S RD L N Sbjct: 63 KPPWADRYAALEVGDVRNEDFLNGVFTRHGP-IDAVVHMCA--FLAVGESVRDPLKYYDN 119 Query: 103 GVKGILHSIKKYAADSVERVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPV 162 V GIL ++ ++++ +SS AA+F S++ N E + + + P Sbjct: 120 NVVGILRLLQAMLLHKCDKIIFSSS-AAIF--GNPTMGSVSTNAEPID----INAKKSPE 172 Query: 163 NAYCGSKKFAEKAAWEFLEENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNS 222 + Y SK AE+ + + ++ + + G D D+ +H S L+ Sbjct: 173 SPYGESKLIAER----MIRDCAEAYGIKGICLRYFNACGAHE-DGDIGEHYQGSTHLIPI 227 Query: 223 LM-----HLSPE-----------DKIPELFGG------------YIDVRDVAKAHLVAFQ 254 ++ ++P+ DK +FG Y+ V D+A AH++A Sbjct: 228 ILGRVMSDIAPDQRLTIHEDASTDKRMPIFGTDYPTPDGTCVRDYVHVCDLASAHILALD 287 Query: 255 KRETIG----QRL-----IVSEARFTMQDVLDILNEDFPVLKGNIPVGKPGSGATHNTLG 305 E +G + + + +++++V+++ + IPV + G Sbjct: 288 YVEKLGPNDKSKYFSVFNLGTSRGYSVREVIEVARK---TTGHPIPVRECGRREGDPAYL 344 Query: 306 ATLDNKKSKKLLGFKFRNLKETIDDTASQILK 337 + K++++LG ++ DT I++ Sbjct: 345 VAASD-KAREVLG--WKPK----YDTLEAIME 369 >4WKG-A nrPDB Length = 660 Score = 169 bits (427), Expect = 2e-42, Method: Composition-based stats. Identities = 65/305 (21%), Positives = 120/305 (39%), Gaps = 59/305 (19%) Query: 2 SVFVSGANGFIAQHIVDLLLKED-YKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISK 60 V + G NGFI H+ + LL+ED Y+V G + + F N+P F V DIS Sbjct: 317 RVLILGVNGFIGNHLTERLLREDHYEVYG----LDIGSDAISRFLNHPHFHF-VEGDISI 371 Query: 61 LDAFDHVFQKHGKDIKIVL----------HTASPFCFDITDSERDLLIPAVNGVKGILHS 110 + + H K +VL +T +P D E +L Sbjct: 372 HSEW---IEYHVKKCDVVLPLVAIATPIEYTRNPLRVFELDFEENL-------------R 415 Query: 111 IKKYAADSVERVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKK 170 I +Y +R++ S+ + V+ M + F+E+ N + P Y SK+ Sbjct: 416 IIRYCVKYRKRIIFPST-SEVYGMCSDK----YFDEDHSNLIVGPV--NKPRWIYSVSKQ 468 Query: 171 FAEKAAWEFLEENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLSPED 230 ++ W + E+ + T P GP++ + + + + +S + +++L Sbjct: 469 LLDRVIWAYGEKE----GLQFTLFRPFNWMGPRLDNLNAAR-IGSSRAITQLILNLVEGS 523 Query: 231 KIPELFGG-----YIDVRDVAKAHLVAFQKRETIGQRLIVS-------EARFTMQDVLDI 278 I + GG + D+RD +A ++ E G R E +++++ ++ Sbjct: 524 PIKLIDGGKQKRCFTDIRDGIEA---LYRIIENAGNRCDGEIINIGNPENEASIEELGEM 580 Query: 279 LNEDF 283 L F Sbjct: 581 LLASF 585 >4LIS-A nrPDB Length = 371 Score = 156 bits (395), Expect = 1e-38, Method: Composition-based stats. Identities = 71/344 (20%), Positives = 117/344 (34%), Gaps = 49/344 (14%) Query: 2 SVFVSGANGFIAQHIVDLLLKEDYKVIGS---ARSQEKAENLTEAF-GNNPKFSMEVVPD 57 SV V+G G+I LL+ YKV+ + S +A N E G +F+ D Sbjct: 5 SVLVTGGTGYIGSFTTLALLEAGYKVVVADNLYNSSAEALNRIELISGKKAEFAQL---D 61 Query: 58 ISKLDAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAAD 117 ++ AFD VF+ H DI V+H A+ E+ L VN V G + ++ Sbjct: 62 VTDEAAFDKVFEAH-PDIDSVIHFAALKAVG-ESGEKPLDYYHVN-VYGTICLLRSMVRH 118 Query: 118 SVERVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAAW 177 +V +V +SS A V+ A + E C P N Y +K E A Sbjct: 119 NVTNIVFSSS-ATVYGDATRFPDMIPIPEH---------CPLGPTNPYGNTKFAIELAIT 168 Query: 178 EFLEENRDS----------VKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLS 227 + + R++ K+ + G + L+ L ++ Sbjct: 169 DVINAQRNNAKKAGNETEAAKWNGALLRYFNPAGAHPSGIMGEDPQGVPYNLLPLLAQVA 228 Query: 228 PEDKIPELFGG-------------YIDVRDVAKAHLVAFQKRET--IGQRLIVSEARFTM 272 + L G YI + D+A HL A G R + Sbjct: 229 TGKREKLLVFGDDYASHDGTAIRDYIHILDLADGHLKALNYLRANNPGVRAW-NLGTGRG 287 Query: 273 QDVLDILNEDFPVLKGNIP---VGKPGSGATHNTLGATLDNKKS 313 V +++ + ++P + + T T N + Sbjct: 288 STVYEMIRAFSKAVGRDLPYEVAPRRAGDVLNLTSNPTRANTEL 331 >1UDA-A nrPDB Length = 338 Score = 121 bits (304), Expect = 4e-28, Method: Composition-based stats. Identities = 73/340 (21%), Positives = 112/340 (32%), Gaps = 37/340 (10%) Query: 1 MSVFVSGANGFIAQHIVDLLLKEDYKVI---GSARSQEKAENLTEAF-GNNPKFSMEVVP 56 M V V+G +G+I H LL+ + VI S+ + E G +P F V Sbjct: 1 MRVLVTGGSGYIGSHTCVQLLQNGHDVIILDNLCNSKRSVLPVIERLGGKHPTF---VEG 57 Query: 57 DISKLDAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAA 116 DI + H I V+H A + +S + L N V G L I A Sbjct: 58 DIRNEALMTEILHDHA--IDTVIHFAGLK--AVGESVQKPLEYYDNNVNGTLRLISAMRA 113 Query: 117 DSVERVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAA 176 +V+ + +SS A V+ + +F P + Y SK E+ Sbjct: 114 ANVKNFIFSSS-ATVYGDNPKIPYVESFP------------TGTPQSPYGKSKLMVEQIL 160 Query: 177 WEFLEENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLSPED------ 230 + + D L NPV +D + N + + + Sbjct: 161 TDLQKAQPDWSIALLRYFNPVGAHPSGDMGEDPQGIPNNLMPYIAQVAVGRRDSLAIFGN 220 Query: 231 KIPELFGG----YIDVRDVAKAHLVAFQKRETIGQRLIVSEARFTMQDVLDILNEDFPVL 286 P G YI V D+A H+VA +K I + VLD++N Sbjct: 221 DYPTEDGTGVRDYIHVMDLADGHVVAMEKLANKPGVHIYNLGAGVGNSVLDVVNAFSKAC 280 Query: 287 KGNIPVGKPGSGATHNTLGATLDNKKSKKLLGFKFRNLKE 326 PV + L A + SK +R + Sbjct: 281 GK--PVNYHFAPRREGDLPAYWADA-SKADRELNWRVTRT 317 >1Z45-A nrPDB Length = 699 Score = 116 bits (291), Expect = 1e-26, Method: Composition-based stats. Identities = 54/270 (20%), Positives = 93/270 (34%), Gaps = 30/270 (11%) Query: 3 VFVSGANGFIAQHIVDLLLKEDYK-VIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKL 61 V V+G G+I H V L++ Y V+ S +++ D+ Sbjct: 14 VLVTGGAGYIGSHTVVELIENGYDCVVADNLSNSTYDSVARLEVLTKHHIPFYEVDLCDR 73 Query: 62 DAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAADSVER 121 + VF+++ I V+H A + +S + L N + G + ++ +V + Sbjct: 74 KGLEKVFKEY--KIDSVIHFAGLK--AVGESTQIPLRYYHNNILGTVVLLELMQQYNVSK 129 Query: 122 VVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAAWEFLE 181 V +SS A V+ A + EE C P N Y +K E + Sbjct: 130 FVFSSS-ATVYGDATRFPNMIPIPEE---------CPLGPTNPYGHTKYAIENILNDLYN 179 Query: 182 ENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLSPEDKIPELFGG--- 238 ++ S KF + G + L L+ + ++ + G Sbjct: 180 SDKKSWKFA--ILRYFNPIGAHPSGLIGEDPLGIPNNLLPYMAQVAVGRREKLYIFGDDY 237 Query: 239 ----------YIDVRDVAKAHLVAFQKRET 258 YI V D+AK H+ A Q E Sbjct: 238 DSRDGTPIRDYIHVVDLAKGHIAALQYLEA 267 >2C20-A nrPDB Length = 330 Score = 105 bits (262), Expect = 2e-23, Method: Composition-based stats. Identities = 62/339 (18%), Positives = 116/339 (34%), Gaps = 49/339 (14%) Query: 2 SVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKL 61 S+ + G G+I H V L+ E V+ + + G D+ Sbjct: 3 SILICGGAGYIGSHAVKKLVDEGLSVVV-VDNLQTGHEDAITEGAK-----FYNGDLRDK 56 Query: 62 DAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAADSVER 121 VF + +I+ V+H A+ ++ L N V G L ++ V++ Sbjct: 57 AFLRDVFTQE--NIEAVMHFAADSLVGVS--MEKPLQYYNNNVYGALCLLEVMDEFKVDK 112 Query: 122 VVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAAWEFLE 181 + SS AA + E D L E N P N Y +K EK + + Sbjct: 113 FIF-SSTAATYG---EVDVDLITEETMTN----------PTNTYGETKLAIEKMLHWYSQ 158 Query: 182 ENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLSPEDKIPELFGG--- 238 + K V G + + + L+ ++ ++ + + G Sbjct: 159 ASNLRYKI----FRYFNVAGAT-PNGIIGEDHRPETHLIPLVLQVALGQREKIMMFGDDY 213 Query: 239 ----------YIDVRDVAKAHLVAFQKRETIGQR--LIVSEAR-FTMQDVLDILNEDFPV 285 YI V D+ AH + + + G+ + F++++++D + E V Sbjct: 214 NTPDGTCIRDYIHVEDLVAAHFLGLKDLQNGGESDFYNLGNGNGFSVKEIVDAVRE---V 270 Query: 286 LKGNIPVGKPGSGATHNTLGATLDNKKSKKLLGFKFRNL 324 IP A ++K+K+ LG+ R + Sbjct: 271 TNHEIPAEVAPRRAGDPARLVA-SSQKAKEKLGWDPRYV 308 >3ENK-A nrPDB Length = 341 Score = 105 bits (262), Expect = 2e-23, Method: Composition-based stats. Identities = 59/295 (20%), Positives = 103/295 (34%), Gaps = 35/295 (11%) Query: 2 SVFVSGANGFIAQHIVDLLLKEDYKVIGSAR----SQEKAENLTEAFGNNPKFSMEVVPD 57 ++ V+G G+I H LL Y V+ + +E + + G P F D Sbjct: 7 TILVTGGAGYIGSHTAVELLAHGYDVVIADNLVNSKREAIARIEKITGKTPAFH---ETD 63 Query: 58 ISKLDAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAAD 117 +S A +F H I +H A+ + +S + N + +L ++ Sbjct: 64 VSDERALARIFDAH--PITAAIHFAALK--AVGESVAKPIEYYRNNLDSLLSLLRVMRER 119 Query: 118 SVERVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAAW 177 +V+R+V +SS A V+ + + + +E N Y +K AE+ Sbjct: 120 AVKRIVFSSS-ATVYGVPERSP----IDETF---------PLSATNPYGQTKLMAEQILR 165 Query: 178 EFLEENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVN--SLMHLSP----EDK 231 + + L NPV + +D N V ++ L Sbjct: 166 DVEAADPSWRVATLRYFNPVGAHESGLIGEDPAGIPNNLMPYVAQVAVGKLEKLRVFGSD 225 Query: 232 IPELFGG----YIDVRDVAKAHLVAFQKRETIGQRLIVSEARFTMQDVLDILNED 282 P G YI V D+A+ H+ A E L V+ VL+++ Sbjct: 226 YPTPDGTGVRDYIHVVDLARGHIAALDALERRDASLTVNLGTGRGYSVLEVVRAF 280 >1I3M-A nrPDB Length = 348 Score = 104 bits (260), Expect = 4e-23, Method: Composition-based stats. Identities = 68/312 (21%), Positives = 108/312 (34%), Gaps = 46/312 (14%) Query: 3 VFVSGANGFIAQHIVDLLLKEDY----------KVIGSARSQEKAENLTEAFGNNPKFSM 52 V V+G G+I H V LL+ Y G E + E G + +F Sbjct: 5 VLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRSVEFEE 64 Query: 53 EVVPDISKLDAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIK 112 DI A +F+K+ V+H A ++ L VN G + ++ Sbjct: 65 M---DILDQGALQRLFKKY--SFMAVIHFAGLKAMG-ESVQKPLDYYRVNLT-GTIQLLE 117 Query: 113 KYAADSVERVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFA 172 A V+ +V +SS A V+ N + L +E N Y SK F Sbjct: 118 IMKAHGVKNLVFSSS-ATVYG----NPQYLPLDEAHPT--------GGCTNPYGKSKFFI 164 Query: 173 EKAAWEFLEENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLSPEDKI 232 E+ + + ++ L NP +D + N V+ + + Sbjct: 165 EEMIRDLCQADKTWNVVLLRYFNPTGAHASGCIGEDPQGIPNNLMPYVSQVA--IGRREA 222 Query: 233 PELFGG------------YIDVRDVAKAHLVAFQK-RETIGQRLIVSEARFTMQDVLDIL 279 +FG YI V D+AK H+ A +K +E G R+ + T VL ++ Sbjct: 223 LNVFGNDYDTEDGTGVRDYIHVVDLAKGHIAALRKLKEQCGCRIY-NLGTGTGYSVLQMV 281 Query: 280 NEDFPVLKGNIP 291 IP Sbjct: 282 QAMEKASGKKIP 293 >4WOK-A nrPDB Length = 336 Score = 103 bits (257), Expect = 1e-22, Method: Composition-based stats. Identities = 60/343 (17%), Positives = 112/343 (32%), Gaps = 44/343 (12%) Query: 3 VFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKLD 62 V V G GFI H LL + Y + + +G+ V DI Sbjct: 14 VLVVGGAGFIGSHTAKLLAGQGYAPVV-YDNLSTGHQSAVRWGDF------VEGDILDQA 66 Query: 63 AFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAADSVERV 122 +K+ V+H A+ + +S D N V G + + V Sbjct: 67 RLVETMEKYAP--VAVIHFAASAY--VGESVEDPAKYYRNNVGGTQSLLDACRLTRTQNV 122 Query: 123 VLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAAWEFLEE 182 + +SS A + + E +P+N Y +K AE ++ Sbjct: 123 IFSSSCAT-YGVPSR-------------LPIGEGEAQNPINPYGRTKLIAEHMLADYA-- 166 Query: 183 NRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLSPEDKIPELFG----- 237 + A+ G + + +KH + + ++M + + E++G Sbjct: 167 --VAYGLRYVALRYFNASGADIDGELGEKHDPETHLIPRAMMAAAGRLDVLEVYGDDYET 224 Query: 238 -------GYIDVRDVAKAHLVAFQKRETIGQRLIVSEARFTMQDVLDILNEDFPVLKGNI 290 YI V D+A+AH++A + + G L V+ + +I+ + ++ Sbjct: 225 PDGTCIRDYIHVTDLARAHVLAVEHLKEAGGNLAVNLGTGRGTSIREIVQSIGRLTGRSV 284 Query: 291 PVGKPGSGATHNTLGATLDNKKSKKLLGFKFRNLKETIDDTAS 333 PV A ++KL F + +D Sbjct: 285 PVAMRARRAGDPPALYADPALAAEKL---GFHTVYSDLDTIIR 324 >1BXK-A nrPDB Length = 355 Score = 84.2 bits (206), Expect = 7e-17, Method: Composition-based stats. Identities = 56/298 (18%), Positives = 102/298 (34%), Gaps = 22/298 (7%) Query: 3 VFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEA--FGNNPKFSMEVVPDISK 60 + ++G GFI +V ++ E + A NL + +F+ E V DI Sbjct: 4 ILITGGAGFIGSALVRYIINETSDAVVVVDKLTYAGNLMSLAPVAQSERFAFEKV-DICD 62 Query: 61 LDAFDHVFQKHGKDIKIVLHTASPFCFDIT-DSERDLLIPAVNGVKGILHSIKKYAADSV 119 VF +H D V+H A+ D + D + + G +L + + Y Sbjct: 63 RAELARVFTEHQPDC--VMHLAAESHVDRSIDGPAAFIETNIVGTYTLLEAARAYWNA-- 118 Query: 120 ERVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAAWEF 179 LT + F + + + S + E+ P + Y SK ++ + Sbjct: 119 ----LTEDKKSAFRFHHISTDEVYGDLHSTDDFFTETTPYAPSSPYSASKASSDHLVRAW 174 Query: 180 LEENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLSPEDKIPELFGGY 239 L + N +GP F + + + + SL +I + + Sbjct: 175 LR----TYGLPTLITNCSNNYGPYHFPEKLIPLMILNALAGKSLPVYGNGQQIRD----W 226 Query: 240 IDVRDVAKAHLVAFQKRETIGQRLIVSEARFTMQ-DVLDILNEDFPVLKGNIPVGKPG 296 + V D A+A L +G+ + DV++ + E L N P G Sbjct: 227 LYVEDHARA-LYCVATTGKVGETYNIGGHNERKNLDVVETICELLEELAPNKPHGVAH 283 >4EJ0-A nrPDB Length = 342 Score = 81.1 bits (198), Expect = 7e-16, Method: Composition-based stats. Identities = 45/290 (15%), Positives = 87/290 (30%), Gaps = 46/290 (15%) Query: 1 MSVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISK 60 M++ V+GA GFI ++V L + I + + +A+ + D Sbjct: 13 MTLIVTGAAGFIGANLVKALNERGETRIIAVDNLTRADKFKNLVD-------CEIDDYLD 65 Query: 61 LDAFDHVF-QKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAADSV 119 F F + ++ V H + TD ++ ++ Sbjct: 66 KTEFVERFARGDFGKVRAVFHEGACSDTMETDG-----RYMMDNNFRYSRAVLDACLAQG 120 Query: 120 ERVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAAWEF 179 + + SS AA++ + + P+N Y SK ++ Sbjct: 121 AQFLYASS-AAIYGGSSRFVEEREVEA--------------PLNVYGYSKFLFDQVIRRV 165 Query: 180 LEENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLSPEDKI------- 232 + K ++ V+GP+ + K S N + Sbjct: 166 M----PGAKSQIAGFRYFNVYGPR----ESHKGRMASVAFHNFNQFRAEGKVKLFGEYSG 217 Query: 233 ---PELFGGYIDVRDVAKAHLVAFQKRETIGQRLIVSEARFTMQDVLDIL 279 E ++ V DVAK +L F E G + + D+ + Sbjct: 218 YGPGEQTRDFVSVEDVAKVNLYFFDHPEKSGIFNLGTGRAQPFNDIAATV 267 >2Q1W-A nrPDB Length = 333 Score = 79.6 bits (194), Expect = 2e-15, Method: Composition-based stats. Identities = 59/327 (18%), Positives = 114/327 (34%), Gaps = 43/327 (13%) Query: 3 VFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKLD 62 VF++G G I HI +LLL+ KV+G + E ++P + V I+ Sbjct: 24 VFITGICGQIGSHIAELLLERGDKVVG-IDNFATG--RREHLKDHPNLTF-VEGSIADHA 79 Query: 63 AFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAADSVERV 122 + + V+HTA+ + D D D L V G + ++ ++V R Sbjct: 80 LVNQLIGDLQP--DAVVHTAASYK-DPDDWYNDTLTNCVGGS----NVVQAAKKNNVGRF 132 Query: 123 VLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAAWEFLEE 182 V + A + + + ++ ++Y SK E ++LE Sbjct: 133 VYFQT-ALCYGVKPIQQP-----------VRLDHPRNPANSSYAISKSANE----DYLE- 175 Query: 183 NRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLSPEDKIPELFGGYIDV 242 + V GP+ + E + + + ++ V Sbjct: 176 ---YSGLDFVTFRLANVVGPRNVSGPLPIFFQRLSE--------GKKCFVTKARRDFVFV 224 Query: 243 RDVAKAHLVAFQKRETIGQRLIVSEARFTMQDVLDILNEDFPVLKGNIPVGKPGSGATHN 302 +D+A+A + A G S ++++ D + E + P + + Sbjct: 225 KDLARATVRAVDGV-GHGAYHFSSGTDVAIKELYDAVVEAMALPS--YPEPEIRELGPDD 281 Query: 303 TLGATLDNKKSKKLLG-FKFRNLKETI 328 LD ++ + G +F LKET+ Sbjct: 282 APSILLDPSRTIQDFGKIEFTPLKETV 308 >6BWL-A nrPDB Length = 328 Score = 76.9 bits (187), Expect = 1e-14, Method: Composition-based stats. Identities = 36/207 (17%), Positives = 71/207 (34%), Gaps = 22/207 (10%) Query: 1 MSVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISK 60 M + V+G GFI + +V LL++ ++V F ++ + DI Sbjct: 1 MKILVTGGAGFIGRWVVKRLLQDKHEVWILDNLANSTTANITEFAHDLNLKQCIQGDIKD 60 Query: 61 LDAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAADSVE 120 +F+ + H A+ ++ DS D N G + +++ V+ Sbjct: 61 KKLVAQLFEN--NSFDLCYHLAA--SINVQDSIDDARATFENDTIGTFNLLEQCLNYDVK 116 Query: 121 RVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAAWEFL 180 +V S+ + +++ + E P + Y GSK AE + Sbjct: 117 -MVFMSTC-------------MVYDKATNIQGISELDPIKPASPYAGSKIAAENMVLSYY 162 Query: 181 EENRDSVKFELTAVNPVYVFGPQMFDK 207 + K + + P +GP Sbjct: 163 ----YAYKLPVVVIRPFNTYGPFQKTG 185 >2PK3-A nrPDB Length = 321 Score = 72.6 bits (176), Expect = 2e-13, Method: Composition-based stats. Identities = 64/344 (18%), Positives = 127/344 (36%), Gaps = 49/344 (14%) Query: 1 MSVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISK 60 M ++G GF+ +++ + L +++ +V G++R+ E P M + DI Sbjct: 13 MRALITGVAGFVGKYLANHLTEQNVEVFGTSRNNE---------AKLPNVEM-ISLDIMD 62 Query: 61 LDAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAADSVE 120 V + H A+ + DS + V G LH + +++ Sbjct: 63 SQRVKKVISDIKP--DYIFHLAAKSS--VKDSWLNKKGTFSTNVFGTLHVLDAVRDSNLD 118 Query: 121 RVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAAWEFL 180 +LT + + M EES E Q P++ Y SK A +++ Sbjct: 119 CRILTIGSSEEYGM--------ILPEES---PVSEENQLRPMSPYGVSKASVGMLARQYV 167 Query: 181 EENRDSVKFELTAVNPVYVFGP-----QMFDKDVKKHLNTSCELVNSLMHLSPEDKIPEL 235 + ++ GP + K+ ++ E ++ + + + + Sbjct: 168 KA----YGMDIIHTRTFNHIGPGQSLGFVTQDFAKQIVDIEMEKQEPIIKVGNLEAVRD- 222 Query: 236 FGGYIDVRDVAKAHLVAFQKRETIGQRLIVSEAR-FTMQDVLDILNEDFPVLKGNIPVGK 294 + DVRD+ +A+ + Q +T G V +QDVLD+L N+ + Sbjct: 223 ---FTDVRDIVQAYWLLSQYGKT-GDVYNVCSGIGTRIQDVLDLLLAM-----ANVKIDT 273 Query: 295 PGSG-ATHNTLGATL--DNKKSKKLLGFKFR-NLKETIDDTASQ 334 + + TL NK+ K G+K R L++++ + Sbjct: 274 ELNPLQLRPSEVPTLIGSNKRLKDSTGWKPRIPLEKSLFEILQS 317 >1R66-A nrPDB Length = 337 Score = 72.6 bits (176), Expect = 3e-13, Method: Composition-based stats. Identities = 49/293 (16%), Positives = 91/293 (31%), Gaps = 50/293 (17%) Query: 1 MSVFVSGANGFIAQHIVDLLLKEDYK--------VIGSARSQEKAENLTEAFGNNPKFSM 52 M + V+G GFI H V LL Y V+ S NL + P+ Sbjct: 1 MRLLVTGGAGFIGSHFVRQLLAGAYPDVPADEVIVLDSLTYAGNRANLAPVDAD-PRLRF 59 Query: 53 EVVPDISKLDAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIK 112 V DI + + + ++H A+ D + + + V+G ++ Sbjct: 60 -VHGDIRDAGLLA----RELRGVDAIVHFAAESHVDRSIAGASVFTET--NVQGTQTLLQ 112 Query: 113 KYAADSVERVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFA 172 V RVV S+ V+ + + SW ES +P + Y SK + Sbjct: 113 CAVDAGVGRVVHVSTD-EVYG---------SIDSGSWT----ESSPLEPNSPYAASKAGS 158 Query: 173 EKAAWEFLEENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLSPEDKI 232 + A + + ++ +GP +L+ + + Sbjct: 159 DLVARAYHR----TYGLDVRITRCCNNYGP----------YQHPEKLIPLFVTNLLDGGT 204 Query: 233 PELFG------GYIDVRDVAKAHLVAFQKRETIGQRLIVSEARFTMQDVLDIL 279 L+G ++ D + + I T +++ IL Sbjct: 205 LPLYGDGANVREWVHTDDHCRGIALVLAGGRAGEIYHIGGGLELTNRELTGIL 257 >2Q1T-A nrPDB Length = 377 Score = 71.1 bits (172), Expect = 6e-13, Method: Composition-based stats. Identities = 58/343 (16%), Positives = 114/343 (33%), Gaps = 33/343 (9%) Query: 3 VFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKLD 62 V V G GF+ ++V LL+ + + AE + +FS + D Sbjct: 35 VMVVGGAGFVGSNLVKRLLELGVNQVHVVDNLLSAEKINVPDHPAVRFSETSITD----- 89 Query: 63 AFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAA-DSVER 121 D + + V H A+ S D L N L ++ +++ Sbjct: 90 --DALLASLQDEYDYVFHLAT--YHGNQSSIHDPLADHENNTLTTLKLYERLKHFKRLKK 145 Query: 122 VVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAAWEFLE 181 VV +++ ++ TF++ T + + Y SK F E + + + Sbjct: 146 VVYSAAGCSIA--------EKTFDDAKATEETDIVSLHNNDSPYSMSKIFGEFYSVYYHK 197 Query: 182 ENR-DSVKFEL-TAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLSPEDKIPELFGG- 238 +++ +V+ P + G + + +P GG Sbjct: 198 QHQLPTVRARFQNVYGPGEILGAGRWRGTPATVWRNVTP--TFIYKALKGMPLPLENGGV 255 Query: 239 ----YIDVRDVAKAHLVAFQKRETIGQRLIVSEARFTMQDVLDILNEDFPVLKGNIPVGK 294 +I V DVA + G I S ++ D+ +NE + K Sbjct: 256 ATRDFIFVEDVANGLIACAADGTPGGVYNIASGKETSIADLATKINEITGNNTELDRLPK 315 Query: 295 PGSGATHNTLGATLDNKKSKKLLGFKFRNLKETIDDTASQILK 337 + G+ +K+++ LGF + +IDD + ++ Sbjct: 316 RPWDNSGKRFGSP---EKARRELGF---SADVSIDDGLRKTIE 352 >1EQ2-A nrPDB Length = 310 Score = 66.5 bits (160), Expect = 2e-11, Method: Composition-based stats. Identities = 43/319 (13%), Positives = 88/319 (27%), Gaps = 43/319 (13%) Query: 3 VFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKLD 62 + V+G GFI +IV L + I + + + + + K D Sbjct: 2 IIVTGGAGFIGSNIVKALNDKGITDILVVDNLKDGTKFVNLV------DLNIADYMDKED 55 Query: 63 AFDHVFQKHG-KDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAADSVER 121 + D++ + H + D ++ + Y + Sbjct: 56 FLIQIMAGEEFGDVEAIFHEGACSSTTEWDG-----KYMMDNNYQYSKELLHYCLEREIP 110 Query: 122 VVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAAWEFLE 181 + SS A + +S + P+N Y SK + E++ Sbjct: 111 FLYASSAATYGGRTSDFIESREYE--------------KPLNVYGYSKFLFD----EYVR 152 Query: 182 ENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLSPEDKIPELFGG--- 238 + ++ V+GP+ + K S + L+ + G Sbjct: 153 QILPEANSQIVGFRYFNVYGPR----EGHKGSMASVAF-HLNTQLNNGESPKLFEGSENF 207 Query: 239 ---YIDVRDVAKAHLVAFQKRETIGQRLIVSEARFTMQDVLDILNEDFPVLKGNIPVGKP 295 ++ V DVA +L + G + + + Q V D + + P Sbjct: 208 KRDFVYVGDVADVNLWFLE-NGVSGIFNLGTGRAESFQAVADATLAYHKKGQIEY-IPFP 265 Query: 296 GSGATHNTLGATLDNKKSK 314 D + Sbjct: 266 DKLKGRYQAFTQADLTNLR 284 >1KEU-A nrPDB Length = 361 Score = 66.1 bits (159), Expect = 2e-11, Method: Composition-based stats. Identities = 58/345 (16%), Positives = 112/345 (32%), Gaps = 42/345 (12%) Query: 1 MSVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEA--FGNNPKFSMEVVPDI 58 M + ++G GFI +V ++K + + A NL + +++ E DI Sbjct: 1 MKILITGGAGFIGSAVVRHIIKNTQDTVVNIDKLTYAGNLESLSDISESNRYNFE-HADI 59 Query: 59 SKLDAFDHVFQKHGKDIKIVLHTASPFCFDIT-DSERDLLIPAVNGVKGILHSIKKY--- 114 +F+++ V+H A+ D + + + G +L +KY Sbjct: 60 CDSAEITRIFEQYQP--DAVMHLAAESHVDRSITGPAAFIETNIVGTYALLEVARKYWSA 117 Query: 115 -AADSVERVVLTS-SYAAVFDMAKENDKSLTFNEESWNPATW-ESCQSDPVNAYCGSKKF 171 D S V+ D+ E S + E+ P + Y SK Sbjct: 118 LGEDKKNNFRFHHISTDEVYGDLPHPDEV----ENSVTLPLFTETTAYAPSSPYSASKAS 173 Query: 172 AEKAAWEFLEENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLSPEDK 231 ++ + R + N +GP F + + + + L D+ Sbjct: 174 SDH----LVRAWRRTYGLPTIVTNCSNNYGPYHFPEKLIPLVILNALEGKPLPIYGKGDQ 229 Query: 232 IPELFGGYIDVRDVAKAHLVAFQKRETIGQRLIVSEARFTMQ-----DVLDILNEDFPVL 286 I + ++ V D A+A L G+ + + D+L+E P Sbjct: 230 IRD----WLYVEDHARA-LHMVVTEGKAGETYNIGGHNEKKNLDVVFTICDLLDEIVPKA 284 Query: 287 -----KGNIPVGKPGSGATHNTLGATLDNKKSKKLLGFKFRNLKE 326 + +PG +D K + LG ++ L+ Sbjct: 285 TSYREQITYVADRPGHD-----RRYAIDAGKISRELG--WKPLET 322 >1WVG-A nrPDB Length = 359 Score = 64.9 bits (156), Expect = 5e-11, Method: Composition-based stats. Identities = 39/205 (19%), Positives = 67/205 (32%), Gaps = 22/205 (10%) Query: 2 SVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKL 61 VFV+G GF + L + V G A +L E + DI Sbjct: 11 RVFVTGHTGFKGSWLSLWLTEMGAIVKGYALDAPTVPSLFEIV-RLNDLMESHIGDIRDF 69 Query: 62 DAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAADSVER 121 + + +I V H A+ ++ + V G +H + ++V++ Sbjct: 70 EKLRSSIAEFKPEI--VFHMAAQPLVRLS--YEQPIKTYSTNVMGTVHLL-----ETVKQ 120 Query: 122 VVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAAWEFLE 181 V + AV ++ + ++ W E+ + Y SK AE A F Sbjct: 121 V---GNIKAVVNITSDK----CYDNREWVWGYRENEPMGGYDPYSNSKGCAELVASAFRN 173 Query: 182 -----ENRDSVKFELTAVNPVYVFG 201 N + L +V V G Sbjct: 174 SFFNPANYEQHGVGLASVRAGNVIG 198 >2X86-A nrPDB Length = 357 Score = 63.8 bits (153), Expect = 9e-11, Method: Composition-based stats. Identities = 42/319 (13%), Positives = 88/319 (27%), Gaps = 43/319 (13%) Query: 3 VFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKLD 62 + V+G GFI +IV L + I + + + + + K D Sbjct: 49 IIVTGGAGFIGSNIVKALNDKGITDILVVDNLKDGTKFVNLV------DLNIADYMDKED 102 Query: 63 AFDHVFQKHG-KDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAADSVER 121 + D++ + H + D ++ + Y + Sbjct: 103 FLIQIMAGEEFGDVEAIFHEGACSSTTEWDG-----KYMMDNNYQYSKELLHYCLEREIP 157 Query: 122 VVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAAWEFLE 181 + SS A + +S + P+N + SK + E++ Sbjct: 158 FLYASSAATYGGRTSDFIESREYE--------------KPLNVFGYSKFLFD----EYVR 199 Query: 182 ENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLSPEDKIPELFGG--- 238 + ++ V+GP+ + K S + L+ + G Sbjct: 200 QILPEANSQIVGFRYFNVYGPR----EGHKGSMASVAF-HLNTQLNNGESPKLFEGSENF 254 Query: 239 ---YIDVRDVAKAHLVAFQKRETIGQRLIVSEARFTMQDVLDILNEDFPVLKGNIPVGKP 295 ++ V DVA +L + G + + + Q V D + + P Sbjct: 255 KRDFVYVGDVADVNLWFLE-NGVSGIFNLGTGRAESFQAVADATLAYHKKGQIEY-IPFP 312 Query: 296 GSGATHNTLGATLDNKKSK 314 D + Sbjct: 313 DKLKGRYQAFTQADLTNLR 331 >1OC2-A nrPDB Length = 348 Score = 63.4 bits (152), Expect = 2e-10, Method: Composition-based stats. Identities = 58/339 (17%), Positives = 115/339 (33%), Gaps = 33/339 (9%) Query: 3 VFVSGANGFIAQHIVDLLLKEDYKVIGSARS----QEKAENLTEAFGNNPKFSMEVVPDI 58 + V+G GFI + V + V + NL G+ + VV DI Sbjct: 7 IIVTGGAGFIGSNFVHYVYNNHPDVHVTVLDKLTYAGNKANLEAILGDRVEL---VVGDI 63 Query: 59 SKLDAFDHVFQKHGKDIKIVLHTASPFCFD-ITDSERDLLIPAVNGVKGILHSIKKYAAD 117 + + D + ++H A+ D + + G +L + +KY Sbjct: 64 ADAELVDKL----AAKADAIVHYAAESHNDNSLNDPSPFIHTNFIGTYTLLEAARKYDI- 118 Query: 118 SVERVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAAW 177 R S+ V+ + E T E+ + P + Y +K ++ Sbjct: 119 ---RFHHVSTD-EVYGDLPLREDLPGHGEGPGEKFTAETNYN-PSSPYSSTKAASDLIVK 173 Query: 178 EFLEENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLSPEDKI-PELF 236 ++ S + T N +GP + ++K + ++ N L + P+ + Sbjct: 174 AWVR----SFGVKATISNCSNNYGPY---QHIEKFIP--RQITNILAGIKPKLYGEGKNV 224 Query: 237 GGYIDVRDVAKAHLVAFQKRETIGQRLIVSEARFTMQDVLDILNEDFPVLKGNIPVGKPG 296 +I D + K LI ++ ++VL+++ E K Sbjct: 225 RDWIHTNDHSTGVWAILTKGRMGETYLIGADGEKNNKEVLELILEKMGQPKDAYDHVTDR 284 Query: 297 SGATHNTLGATLDNKKSKKLLG--FKFRNLKETIDDTAS 333 +G L +D K + LG +F + E +++T Sbjct: 285 AGHD---LRYAIDASKLRDELGWTPQFTDFSEGLEETIQ 320 >2HUN-A nrPDB Length = 336 Score = 62.2 bits (149), Expect = 3e-10, Method: Composition-based stats. Identities = 67/353 (18%), Positives = 131/353 (37%), Gaps = 55/353 (15%) Query: 1 MSVFVSGANGFIAQHIVDLLLKE--DYKVIG--SARSQEKAENLTEAFGNNPKFSMEVVP 56 M + V+G GFI + + +L++ D++VI NL + ++P+++ V Sbjct: 4 MKLLVTGGMGFIGSNFIRYILEKHPDWEVINIDKLGYGSNPANLKDLE-DDPRYTF-VKG 61 Query: 57 DISKLDAFDHVFQKHGKDIKIVLHTASPFCFDIT-DSERDLLIPAVNGVKGILHSIKKYA 115 D++ + ++ + + V+H A+ D + S L V G +L SI++ Sbjct: 62 DVADY----ELVKELVRKVDGVVHLAAESHVDRSISSPEIFLHSNVIGTYTLLESIRREN 117 Query: 116 ADSVERVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKA 175 + R V S+ V+ + + E+ + P + Y +K ++ Sbjct: 118 PEV--RFVHVSTD-EVYGDILKGSFT-------------ENDRLMPSSPYSATKAASDML 161 Query: 176 AWEFLEENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLSPEDKIPEL 235 + + N GP F + + +++ S KIP + Sbjct: 162 VLGWTRTYNLNASITRCTNNY----GPYQFPEKLIPK---------TIIRASLGLKIP-I 207 Query: 236 FGGYIDVRD--VAKAHLVAFQKRETIGQR---LIVSEARFTMQ-DVLDILNEDFPVLKGN 289 +G +VRD + H+ A + G+ +S +V+ I+ + Sbjct: 208 YGTGKNVRDWLYVEDHVRAIELVLLKGESREIYNISAGEEKTNLEVVKIILRLMGKGEEL 267 Query: 290 IPVGKPGSGATHNTLGATLDNKKSKKLLGFKFRN---LKETIDDTASQILKFE 339 I + + G L +LD+ K + L K+R E I T LK E Sbjct: 268 IELVEDRPGHD---LRYSLDSWKITRDL--KWRPKYTFDEGIKKTIDWYLKNE 315 >3SXP-A nrPDB Length = 362 Score = 58.8 bits (140), Expect = 4e-09, Method: Composition-based stats. Identities = 40/301 (13%), Positives = 86/301 (28%), Gaps = 45/301 (14%) Query: 2 SVFVSGANGFIAQHIVDLLLKEDYKVIGSA------------RSQEKAENLTEAFGNNPK 49 ++ ++G GF+ ++ + K + G + Sbjct: 12 TILITGGAGFVGSNLAFHFQENHPKAKVVVLDKFRSNTLFSNNRPSSLGHFKNLIGFKGE 71 Query: 50 FSMEVVPDISKLDAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILH 109 + DI+ + + H + H A+ + + + ++ +L Sbjct: 72 V---IAADINNPLDLRRLEKLH---FDYLFHQAAVSDTTMLN-QELVMKTNYQAFLNLLE 124 Query: 110 SIKKYAADSVERVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSK 169 + A V+ SS V+ K P N Y SK Sbjct: 125 IARSKKAK----VIYASSAG-VYGNTKA--------------PNVVGKNESPENVYGFSK 165 Query: 170 KFAEKAAWEFLEENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLSPE 229 ++ +N + V+GP+ F K+ + L Sbjct: 166 LCMDEFVLSHSNDNVQ------VGLRYFNVYGPREFYKEKTASMVLQLALGAMAFKEVKL 219 Query: 230 DKIPELFGGYIDVRDVAKAHLVAFQKRETIGQRLIVSEARFTMQDVLDILNEDFPVLKGN 289 + E ++ + DV +A++ A K + G + + +++ IL E K Sbjct: 220 FEFGEQLRDFVYIEDVIQANVKAM-KAQKSGVYNVGYSQARSYNEIVSILKEHLGDFKVT 278 Query: 290 I 290 Sbjct: 279 Y 279 >2C54-A nrPDB Length = 379 Score = 58.4 bits (139), Expect = 5e-09, Method: Composition-based stats. Identities = 57/339 (16%), Positives = 122/339 (35%), Gaps = 37/339 (10%) Query: 1 MSVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISK 60 + + ++GA GFIA HI L E + VI S +K E++TE + +V D+ Sbjct: 30 LKISITGAGGFIASHIARRLKHEGHYVIAS--DWKKNEHMTEDMFCDE---FHLV-DLRV 83 Query: 61 LDAFDHVFQKHGKDIKIVLHTASPF-CFDITDSERDLLIPAVNGVKGILHSIKKYAADSV 119 ++ V + + V + A+ S +++ N + I+ + + Sbjct: 84 MENCLKVTE----GVDHVFNLAADMGGMGFIQSNHSVIMY--NNTMISFNMIEAARINGI 137 Query: 120 ERVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAAWEF 179 +R SS + + +++ E ++ ++P +AY + E E Sbjct: 138 KRFFYASSACIYPEFKQLETTNVSLKES-------DAWPAEPQDAYGLERLATE----EL 186 Query: 180 LEENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTS---CELVNSLMHLSPEDKIPELF 236 + E ++GP K ++ + ++ D + Sbjct: 187 CKHYNKDFGIECRIGRFHNIYGPFGTWKGGREKAPAAFCRKAQTSTDRFEMWGDGLQTRS 246 Query: 237 GGYIDVRDVAKAHLVAFQKRETIGQRLIVSEARFTMQDVLDIL----NEDFPVLKGNIPV 292 +I D ++ K + I S+ +M ++ +++ + P+ P Sbjct: 247 FTFI---DECVEGVLRLTKSDFREPVNIGSDEMVSMNEMAEMVLSFEEKKLPIHHIPGPE 303 Query: 293 GKPGSGATHNTLGATL---DNKKSKKLLGFKFRNLKETI 328 G G + +N + L N + K+ L + +KE I Sbjct: 304 GVRGRNSDNNLIKEKLGWAPNMRLKEGLRITYFWIKEQI 342 >3M2P-A nrPDB Length = 311 Score = 58.0 bits (138), Expect = 6e-09, Method: Composition-based stats. Identities = 57/323 (17%), Positives = 113/323 (34%), Gaps = 53/323 (16%) Query: 1 MSVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEV-VPDIS 59 + + V+G GF+ Q++V+ + + I RS GN E V D + Sbjct: 3 LKIAVTGGTGFLGQYVVESIKNDGNTPIILTRS----------IGNKAINDYEYRVSDYT 52 Query: 60 KLDAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAADSV 119 D + + D+ V+H A+ S+ + N + + +++ Sbjct: 53 LEDLINQL-----NDVDAVVHLAA-----TRGSQGKISEFHDNEIL-TQNLYDACYENNI 101 Query: 120 ERVVLTSSYAAVFDMAKENDKSLTFNEE--SWNPATWESCQSDPVNAYCGSKKFAEKAAW 177 +V S+ +A +E WN P Y SK E Sbjct: 102 SNIVYASTISA------------YSDETSLPWNEKELPL----PDLMYGVSKLACEHIGN 145 Query: 178 EFLEENRDSVKFELTAVNPVYVFGPQMFDK-DVKKHLNTSCELVNSLMHLSPEDKIPELF 236 + + + + +++G + + + + +H + K Sbjct: 146 IYSRKK----GLCIKNLRFAHLYGFNEKNNYMINRFFRQAFHGEQLTLHANSVAKR---- 197 Query: 237 GGYIDVRDVAKAHLVAFQKRETIGQRLIVSEARFTMQDVLDILNEDFPVLKGNIPVGKPG 296 ++ +D AK+ + A ++ + G I S T +V + +N F K N+ V P Sbjct: 198 -EFLYAKDAAKSVIYALKQEKVSGTFNIGSGDALTNYEVANTINNAF-GNKDNLLVKNP- 254 Query: 297 SGATHNTLGATLDNKKSKKLLGF 319 A + +D+ K+K+LL F Sbjct: 255 -NANEGIHSSYMDSSKAKELLDF 276 >6BI4-A nrPDB Length = 346 Score = 57.6 bits (137), Expect = 7e-09, Method: Composition-based stats. Identities = 48/249 (19%), Positives = 102/249 (40%), Gaps = 39/249 (15%) Query: 1 MSVFVSGANGFIAQHIVDLLLK--EDYKVIGSARSQEKAENL--TEAFGNNPKFSMEVVP 56 M++ V+G GFI + V +L+ E YK+I + + + NL ++ ++P + V Sbjct: 25 MNILVTGGAGFIGSNFVHYMLQSYETYKII-NFDALTYSGNLNNVKSIQDHPNY-YFVKG 82 Query: 57 DISKLDAFDHVFQKHGKDIKIVLHTASPFCFDIT-DSERDLLIPAVNGVKGILHSIKKYA 115 +I + +HV ++ +D++++++ A+ D + ++ V G +L +KKY Sbjct: 83 EIQNGELLEHVIKE--RDVQVIVNFAAESHVDRSIENPIPFYDTNVIGTVTLLELVKKYP 140 Query: 116 ADSVERVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKA 175 + +V S V+ E P + Y SK A+ Sbjct: 141 HIKLVQV----STDEVY--GSLGKTGRFTEETP----------LAPNSPYSSSKASADMI 184 Query: 176 AWEFLEENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLSPEDKIPEL 235 A + + + + + +GP + + +L+ ++ + E K L Sbjct: 185 ALAYYK----TYQLPVIVTRCSNNYGPYQYPE----------KLIPLMVTNALEGKKLPL 230 Query: 236 FGGYIDVRD 244 +G ++VRD Sbjct: 231 YGDGLNVRD 239 >1RKX-A nrPDB Length = 357 Score = 56.8 bits (135), Expect = 1e-08, Method: Composition-based stats. Identities = 47/270 (17%), Positives = 80/270 (29%), Gaps = 32/270 (11%) Query: 2 SVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKL 61 VFV+G GF + L V G + + +L E + DI Sbjct: 11 RVFVTGHTGFKGGWLSLWLQTMGATVKGYSLTAPTVPSLFET-ARVADGMQSEIGDIRDQ 69 Query: 62 DAFDHVFQKHGKDIKIVLHTAS-PFCFDITDSERDLLIPAVNGVKGILHSIKKYAADSVE 120 + ++ +I V H A+ P + V G +L +I+ V+ Sbjct: 70 NKLLESIREFQPEI--VFHMAAQPLVRLSYSEPVETYSTNVMGTVYLLEAIRHVGG--VK 125 Query: 121 RVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAAWEFL 180 VV +S ++ + W E+ + Y SK AE + Sbjct: 126 AVVNITS-------------DKCYDNKEWIWGYRENEAMGGYDPYSNSKGCAELVTSSYR 172 Query: 181 E-----ENRDSVKFELTAVNPVYVF--GPQMFDKDVKKHLNTSCELVNSLMHLSPEDKIP 233 N + V V G D+ V L + ++ + P Sbjct: 173 NSFFNPANYGQHGTAVATVRAGNVIGGGDWALDRIVPDILRAFEQSQPVII------RNP 226 Query: 234 ELFGGYIDVRDVAKAHLVAFQKRETIGQRL 263 + V + +L+ QK T G Sbjct: 227 HAIRPWQHVLEPLSGYLLLAQKLYTDGAEY 256 >1DB3-A nrPDB Length = 372 Score = 55.3 bits (131), Expect = 4e-08, Method: Composition-based stats. Identities = 41/253 (16%), Positives = 93/253 (36%), Gaps = 36/253 (14%) Query: 4 FVSGANGFIAQHIVDLLLKEDYKVIGSAR-----SQEKAENL-TEAFGNNPKFSMEVVPD 57 ++G G ++ + LL++ Y+V G R + E+ +++ + NPKF + D Sbjct: 5 LITGVTGQDGSYLAEFLLEKGYEVHGIKRRASSFNTERVDHIYQDPHTCNPKFHLHY-GD 63 Query: 58 ISKLDAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAAD 117 +S + ++ D L S E + A+ G +L +I+ + Sbjct: 64 LSDTSNLTRILREVQPDEVYNLGAMSHVAVSFESPEYTADVDAM-GTLRLLEAIRFLGLE 122 Query: 118 SVERVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAAW 177 R +S + ++ + +E + E+ P + Y +K +A W Sbjct: 123 KKTRF-YQASTSELYGLVQEIPQK-------------ETTPFYPRSPYAVAKLYA---YW 165 Query: 178 EFLEENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNT--SCELVNSLMHLSPEDKIPEL 235 + R+S Y +F+ + + T + ++ ++ +++ + Sbjct: 166 ITVNY-RESYGM--------YACNGILFNHESPRRGETFVTRKITRAIANIAQGLESCLY 216 Query: 236 FGGYIDVRDVAKA 248 G +RD A Sbjct: 217 LGNMDSLRDWGHA 229 >1ORR-A nrPDB Length = 347 Score = 54.1 bits (128), Expect = 8e-08, Method: Composition-based stats. Identities = 35/267 (13%), Positives = 81/267 (30%), Gaps = 17/267 (6%) Query: 3 VFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAE-NLTEAFGNNPKFSMEVVPDISKL 61 + ++G GF+ ++ L + +I K + + F V DI Sbjct: 4 LLITGGCGFLGSNLASFALSQGIDLIVFDNLSRKGATDNLHWLSSLGNFEF-VHGDIRNK 62 Query: 62 DAFDHVFQKHGKDIKIVLHTASPFCFDIT-DSERDLLIPAVNGVKGILHSIKKYAADSVE 120 + + K+ H A + D+ V G +L ++++Y ++ Sbjct: 63 NDVTRLITKYMP--DSCFHLAGQVAMTTSIDNPCMDFEINVGGTLNLLEAVRQYNSNC-- 118 Query: 121 RVVLTSSYAAVFDMAKENDKSLTFNEESWNPATW--ESCQSDPVNAYCGSKKFAEKAAWE 178 ++ +S+ D+ + + ES Q D + Y SK A++ + Sbjct: 119 NIIYSSTNKVYGDLEQYKYNETETRYTCVDKPNGYDESTQLDFHSPYGCSKGAADQYMLD 178 Query: 179 FLEENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLSPEDKIPELFGG 238 + ++G + F + + C+ + + + G Sbjct: 179 YAR----IFGLNTVVFRHSSMYGGRQFATYDQGWVGWFCQKAVEIKNGINKPFTISGNGK 234 Query: 239 YI----DVRDVAKAHLVAFQKRETIGQ 261 + D+ + A I Sbjct: 235 QVRDVLHAEDMISLYFTALANVSKIRG 261 >2PZM-A nrPDB Length = 330 Score = 53.4 bits (126), Expect = 2e-07, Method: Composition-based stats. Identities = 26/213 (12%), Positives = 73/213 (34%), Gaps = 33/213 (15%) Query: 1 MSVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISK 60 M + ++G G + ++++ L + ++++ + + E S+ + ++ Sbjct: 21 MRILITGGAGCLGSNLIEHWLPQGHEILV-IDNFATGK--REVLPPVAGLSV-IEGSVTD 76 Query: 61 LDAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAADSVE 120 + F V+H+A+ + D A V+G ++ K + V+ Sbjct: 77 AGLLERAFDSFKP--THVVHSAAAYK-----DPDDWAEDAATNVQGSINVAKAASKAGVK 129 Query: 121 RVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAAWEFL 180 R++ ++ + + + + P +Y SK E A+ + Sbjct: 130 RLL---NFQTALCYGRPATVPIPID-----------SPTAPFTSYGISKTAGE--AFLMM 173 Query: 181 EENRDSVKFELTAVNPVYVFGPQMFDKDVKKHL 213 + + ++ V GP++ + Sbjct: 174 SD------VPVVSLRLANVTGPRLAIGPIPTFY 200 >4G5H-A nrPDB Length = 363 Score = 53.0 bits (125), Expect = 2e-07, Method: Composition-based stats. Identities = 41/265 (15%), Positives = 90/265 (33%), Gaps = 22/265 (8%) Query: 3 VFVSGANGFIAQHIVDLLLKEDYK-VIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKL 61 + ++G G ++ L + K + +R ++K +++ + + NN K + D+ Sbjct: 28 LLITGGTGSFGNAVMKRFLDSNIKEIRIFSRDEKKQDDIRKKY-NNSKLKFYI-GDVRDS 85 Query: 62 DAFDHVFQKHGKDIKIVLHTASPFCFDITD-SERDLLIPAVNGVKGILHSIKKYAADSVE 120 + + +D+ V H A+ + + + + G + +L S +V+ Sbjct: 86 QS----VETAMRDVDYVFHAAALKQVPSCEFFPVEAVKTNIIGTENVLQSAIH---QNVK 138 Query: 121 RVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAAWEFL 180 +V+ S+ A + + + + + + A + + L Sbjct: 139 KVICLSTDKAAYPINAMGISKAMMEKVFVAKSRNIRSEQTLICGTRYGNVMASRGSVIPL 198 Query: 181 EENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLSPEDKIPELFGGYI 240 ++ LT +P + L + ELV + I Sbjct: 199 FIDKIKAGEPLTITDPDMT--RFLMS------LEDAVELVVHAFKHAETGDIMVQKAPSS 250 Query: 241 DVRDVAKAHLVAFQKR---ETIGQR 262 V D+A A L F+ E IG R Sbjct: 251 TVGDLATALLELFEADNAIEIIGTR 275 >2GN9-A nrPDB Length = 344 Score = 53.0 bits (125), Expect = 2e-07, Method: Composition-based stats. Identities = 34/207 (16%), Positives = 77/207 (37%), Gaps = 45/207 (21%) Query: 2 SVFVSGANGFIAQHIVDLLLK--EDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDIS 59 ++ ++G G + V +L K+I +R + K + N+P+ + D+ Sbjct: 23 TILITGGTGSFGKCFVRKVLDTTNAKKIIVYSRDELKQSEM-AMEFNDPRMRF-FIGDVR 80 Query: 60 KLDAFDHVFQKHGKDIKIVLHTASPFCFDITD-SERDLLIPAVNGVKGILHSIKKYAADS 118 L+ ++ + + I +H A+ I + + + + + G ++++ K A Sbjct: 81 DLERLNYALE----GVDICIHAAALKHVPIAEYNPLECIKTNIMGASNVINACLKNAISQ 136 Query: 119 VERVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAAWE 178 V + L++ AA +P+N Y +K ++K Sbjct: 137 V--IALSTDKAA-----------------------------NPINLYGATKLCSDKL--- 162 Query: 179 FLEENR--DSVKFELTAVNPVYVFGPQ 203 F+ N S + + + V V G + Sbjct: 163 FVSANNFKGSSQTQFSVVRYGNVVGSR 189 >4BKP-A nrPDB Length = 336 Score = 52.6 bits (124), Expect = 3e-07, Method: Composition-based stats. Identities = 54/339 (15%), Positives = 103/339 (30%), Gaps = 46/339 (13%) Query: 1 MSVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISK 60 M + V+G +G + + I Q+ + G + F D++ Sbjct: 23 MRILVTGGSGLVGKAI-----------------QKVVADGAGLPGEDWVFVSSKDADLTD 65 Query: 61 LDAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLL--IPAVNGVKGILHSIKKYAADS 118 +F+K V+H A+ + + +L V+ +LHS + A Sbjct: 66 TAQTRALFEKVQP--THVIHLAAMVGGLFRNIKYNLDFWRKNVHMNDNVLHSAFEVGARK 123 Query: 119 VERVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAAWE 178 V S + K +E + Y +K+ + Sbjct: 124 V-----VSCLSTCIFPDKTTYP---IDET----MIHNGPPHNSNFGYSYAKRMIDVQNRA 171 Query: 179 FLEENRDSVKFELTAVNPVYVFGPQ----MFDKDVKKHLNTSCELVNSLMHLSPEDKIPE 234 + ++ TAV P VFGP + D V L L S Sbjct: 172 YFQQ----YGCTFTAVIPTNVFGPHDNFNIEDGHVLPGLIHKVHLAKSSGSALTVWGTGN 227 Query: 235 LFGGYIDVRDVAKAHLVAF-QKRETIGQRL-IVSEARFTMQDVLDILNEDFPVLKGNIPV 292 +I D+A+ + + E L + E ++++ + + E G + Sbjct: 228 PRRQFIYSLDLAQLFIWVLREYNEVEPIILSVGEEDEVSIKEAAEAVVEAM-DFHGEVTF 286 Query: 293 GKPGSGATHNTLGATLDNKKSKKLLGFKFRNLKETIDDT 331 S ++K L F+F K+ + +T Sbjct: 287 DTTKSDG--QFKKTASNSKLRTYLPDFRFTPFKQAVKET 323 >3RUE-A nrPDB Length = 351 Score = 52.2 bits (123), Expect = 3e-07, Method: Composition-based stats. Identities = 46/302 (15%), Positives = 97/302 (32%), Gaps = 42/302 (13%) Query: 4 FVSGANGFIAQHIVDLLLKEDYKVIGSAR-------SQEKAENLTEAFGNNPKFSMEVVP 56 ++G GFI ++++ LLK + VIG + ++ + L +F + Sbjct: 29 LITGVAGFIGSNLLEKLLKLNQVVIGLDNFSTGHQYNLDEVKTLVSTE-QWSRFCF-IEG 86 Query: 57 DISKLDAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGI---LHSIKK 113 DI L + V K + VLH A+ + R ++ P I L+ + Sbjct: 87 DIRDLTTCEQVM----KGVDHVLHQAA-----LGSVPRSIVDPITTNATNITGFLNILHA 137 Query: 114 YAADSVERVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAE 173 V+ +S + + +L EE+ +P++ Y +K E Sbjct: 138 AKNAQVQSFTYAASSST-----YGDHPALPKVEENIG---------NPLSPYAVTKYVNE 183 Query: 174 KAAWEFLEENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLSPEDKIP 233 A + + F+ + VFG + + + Sbjct: 184 IYAQVYAR----TYGFKTIGLRYFNVFGRRQDPNGAYAAVIPKWTAAMLKGDDVYINGDG 239 Query: 234 ELFGGYIDVRDVAKAHLV-AFQKRETIGQRLIVSEARFTMQDVLDILNEDFPVLKGNIPV 292 E + + +V + +++ A K V+ + ++ + L + Sbjct: 240 ETSRDFCYIDNVIQMNILSALAKDSAKDNIYNVAVG--DRTTLNELSGYIYDELNLIHHI 297 Query: 293 GK 294 K Sbjct: 298 DK 299 >5UZH-A nrPDB Length = 345 Score = 51.1 bits (120), Expect = 8e-07, Method: Composition-based stats. Identities = 35/267 (13%), Positives = 91/267 (34%), Gaps = 40/267 (14%) Query: 4 FVSGANGFIAQHIVDLLLKEDYKVIGSAR-----SQEKAENL-TEAFGNNPKFSMEVVPD 57 ++G G ++ + LL++ Y V G R + + E+L + KF + + D Sbjct: 5 LITGITGQDGSYLAEFLLEKGYMVYGIIRRSSSFNTGRVEHLYKDIHITKAKFKL-LYGD 63 Query: 58 ISKLDAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVN----GVKGILHSIKK 113 ++ + K + + A+ ++ ++ N G +L +I+ Sbjct: 64 LTDTGNLISIIAKIKP--DEIYNLAAQSHVKVS---FEMPEYTANVDGIGTLRLLEAIRA 118 Query: 114 YAADSVERVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAE 173 + + +S + ++ + +E + E+ P + Y +K + Sbjct: 119 CGLEKKTKF-YQASTSELYGLVQEVPQK-------------ETTPFYPRSPYACAKLY-- 162 Query: 174 KAAWEFLEENRDSVKFELTAVNPVYVF---GPQMFDKDVKKHLNTSCELVNSLMHLSPED 230 + W + F L + + GP + + + + ++L D Sbjct: 163 -SYWIVVNYREAYNMFALNGILFNHESIRRGPTFVTRKITMAVARIKLGLQDCLYLGNLD 221 Query: 231 KIPELFGGYIDVRDVAKAHLVAFQKRE 257 + + +D +A + Q+ + Sbjct: 222 AERD----WGHAKDYVEAMWLMLQQEQ 244 >6AQY-A nrPDB Length = 341 Score = 49.9 bits (117), Expect = 2e-06, Method: Composition-based stats. Identities = 55/349 (15%), Positives = 101/349 (28%), Gaps = 55/349 (15%) Query: 3 VFVSGANGFIA---QHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDIS 59 + V+G G +HIV E F D+ Sbjct: 27 ILVTGGTGLFGKAVEHIVK----------------------KEQIKGKWVFLGSKDGDLR 64 Query: 60 KLDAFDHVFQKHGKDIKIVLHTASPFC--FDITDSERDLLIPAVNGVKGILHSIKKYAAD 117 DA F+K+ V+H A+ F + + + VN IL + Sbjct: 65 DADACKQPFEKYRP--TYVIHLAAFVGGLFKNMNFKVSFWLDNVNMNNNILTCCYDFGVK 122 Query: 118 SVERVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAE-KAA 176 + + + + EE + E NAY +K+ + Sbjct: 123 K--------TISCLSTCVFPDKIEYPITEEKLH----EGPPHFSNNAYAYAKRMLDMLGR 170 Query: 177 WEFLEENRDSVKFELTAVNPVYVFGPQ-MFDKDVKKHLNTSCELV-----NSLMHLSPED 230 W + + T+V P +FGP F+ + L N + Sbjct: 171 WYNEKAVNEGKSCLFTSVIPTNLFGPHDNFNVEAGHVLPGLMHKCYKAQQNGTDFVVFGS 230 Query: 231 KIPELFGGYIDVRDVAKAHLVAFQKRETIGQRLIV--SEARFTMQDVLDILNEDFPVLKG 288 P Y D A+ L ++ ++ E ++ V + + F G Sbjct: 231 GKPLRQFLYSH--DAARMLLWTMFNYQSEEPIMLCVSEEDEKSIGQVAQTIKDAF-NFTG 287 Query: 289 NIPVGKPGSGATHNTLGATLDNKKSKKLLGFKFRNLKETIDDTASQILK 337 N+ S A + + K + F++ ++ I +T L+ Sbjct: 288 NMVFDT--SKADGQYKKTSSNAKFLRLNPTFQYTPFEQAIKETVQWFLE 334 >5U9C-A nrPDB Length = 292 Score = 49.5 bits (116), Expect = 2e-06, Method: Composition-based stats. Identities = 57/325 (17%), Positives = 100/325 (30%), Gaps = 65/325 (20%) Query: 3 VFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKLD 62 + ++G G + ++ L DY VI + R+ ++S + Sbjct: 8 ILITGGTGMLGAYVTSALKDTDYNVIVTERN---------------------TLNLSVPE 46 Query: 63 AFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHS-IKKYAADSVER 121 A ++LH A+ D+ + E PA G+ L + AA Sbjct: 47 AIFSYITAEKP--DVILHFAAETDVDLCERE-----PARAGIYNHLATEQIAQAAKFCGA 99 Query: 122 VVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAAWEFLE 181 +L S + VF + L++NE P+N Y SK E + Sbjct: 100 WLLYLSSSNVFG----GEGKLSYNELDIPL---------PMNYYGRSKLIGESSV----- 141 Query: 182 ENRDSVKFELTAVNPVYVF--GPQMFDKDVKKHLNTSCELVNSLMHLSPEDKIPELFGGY 239 R++ + ++ GP K V K + S+ +S G Sbjct: 142 --RNACTNNHLIIRAGWMIGGGPDKDHKFVGKIIQQIKAGSTSIKAVSDR------LGSI 193 Query: 240 IDVRDVAKAHLVAFQKRETIGQRLIVSEAR------FTMQDVLDILNEDFPVLKGNIP-- 291 + + A KR T S + D+L+ + PV P Sbjct: 194 TSAMQLCNFIIWAINKRHTGTLHFASSGTISRFDIACAIGDLLNFKGDIIPVHSSVFPLS 253 Query: 292 VGKPGSGATHNTLGATLDNKKSKKL 316 +P S + + L + L Sbjct: 254 APRPYSEGIESIYMSILSDAPKPSL 278 >4J2O-A nrPDB Length = 363 Score = 48.7 bits (114), Expect = 4e-06, Method: Composition-based stats. Identities = 22/136 (16%), Positives = 57/136 (41%), Gaps = 13/136 (9%) Query: 3 VFVSGANGFIAQHIVDLLLKEDYK-VIGSARSQEKAENLTEAF-GNNPKFSMEVVPDISK 60 + ++G G ++ L+ D K + +R ++K +++ + + KF + D+ Sbjct: 26 LLITGGTGSFGNAVLKRFLETDIKEIRIFSRDEKKQDDMRKKYHSAKLKF---YIGDVRD 82 Query: 61 LDAFDHVFQKHGKDIKIVLHTASPFCFDITDS-ERDLLIPAVNGVKGILHSIKKYAADSV 119 ++ + + + H A+ + + + V G + +L + + + V Sbjct: 83 YNS----ILNATRGVDYIYHAAALKQVPSCEFHPMEAVKTNVLGTENVLEAAIQ---NHV 135 Query: 120 ERVVLTSSYAAVFDMA 135 +RVV S+ AV+ + Sbjct: 136 KRVVCLSTDKAVYPIN 151 >3WMX-A nrPDB Length = 358 Score = 48.4 bits (113), Expect = 4e-06, Method: Composition-based stats. Identities = 40/302 (13%), Positives = 88/302 (29%), Gaps = 55/302 (18%) Query: 3 VFVSGANGFIAQHIVDLLLKE-DYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKL 61 + + GANG I + L + + ++ ++ + + + Sbjct: 28 ILIVGANGQIGSELALALAERYGRTNVITSDVVPTGRHV---------HLTHEMLNATDR 78 Query: 62 DAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAADSVER 121 V ++HG I V A+ E+ + +L+ ++ +ER Sbjct: 79 GELATVVERHG--ITQVYLLAAAL---SATGEKAPQWAWNLNMTSLLNVLELARQTGLER 133 Query: 122 VVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAAWEFLE 181 V SS AA F ++ + +P Y SK+ E W Sbjct: 134 VFWPSSIAA-FGPTTPAGQTP------------QKTVMEPTTVYGISKQAGE--GW--CR 176 Query: 182 ENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELV----------NSLMHLSPEDK 231 + ++ +V P + T+ V L ++ Sbjct: 177 WYHANHGVDVRSVRY-----PGLISHKTPPGGGTTDYAVDIFHAAVTGEPYTCFLKEDEA 231 Query: 232 IPELFGGYIDVRDVAKAHLVAFQKRE---TIGQRLIVSEARFTMQDVLDILNEDFPVLKG 288 +P ++ + D +A + + + ++ FT + + E P + Sbjct: 232 LPMMY-----MPDAIRATIELMEAPADKLSERGSYNIAGMSFTPAQIAAAIREQVPGFQI 286 Query: 289 NI 290 Sbjct: 287 RY 288 >1RPN-A nrPDB Length = 335 Score = 47.6 bits (111), Expect = 8e-06, Method: Composition-based stats. Identities = 36/221 (16%), Positives = 72/221 (32%), Gaps = 25/221 (11%) Query: 2 SVFVSGANGFIAQHIVDLLLKEDYKVIGSA--RSQEKAENLTEAFGNNPKFSMEVVPDIS 59 S V+G G ++ LLL++ Y+V G RS + L E G E D++ Sbjct: 16 SALVTGITGQDGAYLAKLLLEKGYRVHGLVARRSSDTRWRLREL-GIEGDIQYE-DGDMA 73 Query: 60 KLDAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAADSV 119 + K V + A+ + + V G+ H ++ S Sbjct: 74 DACSVQRAVIKAQPQ--EVYNLAAQSFVGAS--WNQPVTTGVVDGLGVTHLLEAIRQFSP 129 Query: 120 ERVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAAWEF 179 E +S + +F + + + E+ P + Y +K + W Sbjct: 130 ETRFYQASTSEMFGLIQAERQD-------------ENTPFYPRSPYGVAKLYGH---WIT 173 Query: 180 LEENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELV 220 + R+S ++ P + V + + + + Sbjct: 174 VNY-RESFGLHASSGILFNHESPLRGIEFVTRKVTDAVARI 213 >2Z95-A nrPDB Length = 345 Score = 47.2 bits (110), Expect = 1e-05, Method: Composition-based stats. Identities = 25/170 (14%), Positives = 59/170 (34%), Gaps = 17/170 (10%) Query: 2 SVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKL 61 ++G G ++ LLL++ Y+V G+ R + + + D+ + Sbjct: 5 RALITGIRGQDGAYLAKLLLEKGYEVYGADRRSGEFASWRLKELGIENDVKIIHMDLLEF 64 Query: 62 DAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAADSVER 121 +K V + A+ ++ E+ +L V+ G+L ++ + Sbjct: 65 SNIIRTIEKVQP--DEVYNLAAQSFVGVS-FEQPILTAEVD-AIGVLRILEALRTVKPDT 120 Query: 122 VVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKF 171 +S + +F + + E++ P + Y +K F Sbjct: 121 KFYQASTSEMFG----KVQEIPQTEKT---------PFYPRSPYAVAKLF 157 >1N7G-A nrPDB Length = 381 Score = 47.2 bits (110), Expect = 1e-05, Method: Composition-based stats. Identities = 23/176 (13%), Positives = 53/176 (30%), Gaps = 12/176 (6%) Query: 4 FVSGANGFIAQHIVDLLLKEDYKVIGSARSQEK-AENLTEAFGNNPK-----FSMEVVPD 57 ++G G ++ + LL + Y+V G R +P D Sbjct: 32 LITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKLHYAD 91 Query: 58 ISKLDAFDHVFQKHGKDIKIVLHTASPFCFDIT-DSERDLLIPAVNGVKGILHSIKKYAA 116 ++ + V + A+ ++ + G +L +++ + Sbjct: 92 LTDASSLRRWIDVIKP--DEVYNLAAQSHVAVSFEIPDYTADVVATGALRLLEAVRSHTI 149 Query: 117 DSVERVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFA 172 DS V + ++ + +S T +P C + Y + + A Sbjct: 150 DSGRTVKYYQAGSSEMFGSTPPPQSETTPFHPRSPYAASKCAAH---WYTVNYREA 202 >6GCS-E nrPDB Length = 375 Score = 46.8 bits (109), Expect = 1e-05, Method: Composition-based stats. Identities = 31/176 (17%), Positives = 61/176 (34%), Gaps = 13/176 (7%) Query: 2 SVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKL 61 + V GANGF+ ++ L K V+ R +E A+ + G+ + + D+ L Sbjct: 55 TATVFGANGFLGSYLTAKLAKHGTTVVVPYR-EEMAKRHLKVTGDLGVVNFLEM-DLRNL 112 Query: 62 DAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAADSVER 121 ++ D V H+ + E V+G + ++ R Sbjct: 113 ESIDEA----------VRHSDIVVNLIGREYETKNFNYYDVHVEGARRIAEAVKKHNIAR 162 Query: 122 VVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYC-GSKKFAEKAA 176 + S++ A D E + + E+ + P + K F ++ A Sbjct: 163 YIHVSAFNAEIDSPSEFNHTKGLGEQVTKDIVPWATIVRPAPMFGREDKWFLDRMA 218 >6GPK-A nrPDB Length = 373 Score = 45.7 bits (106), Expect = 3e-05, Method: Composition-based stats. Identities = 34/263 (12%), Positives = 81/263 (30%), Gaps = 27/263 (10%) Query: 4 FVSGANGFIAQHIVDLLLKEDYKVIGSA-RSQEKAENLTEAFGNNPKFSMEVV-----PD 57 ++G G ++ + LL++ Y+V G RS E NP+ +E D Sbjct: 28 LITGITGQDGSYLAEFLLEKGYEVHGIVRRSSSFNTGRIEHLYKNPQAHIEGNMKLHYGD 87 Query: 58 ISKLDAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVN-GVKGILHSIKKYAA 116 ++ + + + + + I+ + G +L ++K Sbjct: 88 LTDSTCLVKIINEVKP--TEIYNLGAQSHVKISFDLAEYTADVDGVGTLRLLDAVKTCGL 145 Query: 117 DSVERVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAA 176 + + +S + ++ +E + E+ P + Y +K +A Sbjct: 146 INSVKF-YQASTSQLYGKVQEIPQK-------------ETTPFYPRSPYGAAKLYA---Y 188 Query: 177 WEFLEENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLSPEDKIPELF 236 W + F + + P+ V + ++ S + + Sbjct: 189 WIVVNFREAYNLFAVNGIL-FNHESPRRGANFVTRKISRSVAKIYLGQLECFSLGNLDAK 247 Query: 237 GGYIDVRDVAKAHLVAFQKRETI 259 + +D +A + Q E Sbjct: 248 RDWGHAKDYVEAMWLMLQNDEPE 270 >5OVL-A nrPDB Length = 300 Score = 44.9 bits (104), Expect = 6e-05, Method: Composition-based stats. Identities = 22/145 (15%), Positives = 48/145 (33%), Gaps = 20/145 (13%) Query: 2 SVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKL 61 SV V+G N I I L + +KV + R ++L V D++ Sbjct: 70 SVLVTGGNRGIGLAIARRLAADGHKVAVTHRGSGAPDDL-----------FGVQCDVTDS 118 Query: 62 DAFDHVF---QKHGKDIKIVLHTAS------PFCFDITDSERDLLIPAVNGVKGILHSIK 112 A D F ++H +++++ A E + + + + Sbjct: 119 AAVDRAFKEVEEHQGPVEVLVANAGISKDAFLMRMTEERFEEVINTNLTGAFRCAQRASR 178 Query: 113 KYAADSVERVVLTSSYAAVFDMAKE 137 R++ S + ++ + + Sbjct: 179 TMQRKRFGRIIFIGSVSGMWGIGNQ 203 >5OVJ-A nrPDB Length = 256 Score = 44.9 bits (104), Expect = 6e-05, Method: Composition-based stats. Identities = 22/145 (15%), Positives = 48/145 (33%), Gaps = 20/145 (13%) Query: 2 SVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKL 61 SV V+G N I I L + +KV + R ++L V D++ Sbjct: 26 SVLVTGGNRGIGLAIARRLAADGHKVAVTHRGSGAPDDL-----------FGVQCDVTDS 74 Query: 62 DAFDHVF---QKHGKDIKIVLHTAS------PFCFDITDSERDLLIPAVNGVKGILHSIK 112 A D F ++H +++++ A E + + + + Sbjct: 75 AAVDRAFKEVEEHQGPVEVLVANAGISKDAFLMRMTEERFEEVINTNLTGAFRCAQRASR 134 Query: 113 KYAADSVERVVLTSSYAAVFDMAKE 137 R++ S + ++ + + Sbjct: 135 TMQRKRFGRIIFIGSVSGMWGIGNQ 159 >3SLK-A nrPDB Length = 795 Score = 43.7 bits (101), Expect = 1e-04, Method: Composition-based stats. Identities = 29/147 (19%), Positives = 51/147 (34%), Gaps = 19/147 (12%) Query: 2 SVFVSGANGFIAQHIVDLL-LKEDYK--VIGSARSQEK--AENLTEAFGNNPKFSMEVVP 56 +V V+G G + + L ++ + V+ S R A L Sbjct: 532 TVLVTGGTGALGAEVARHLVIERGVRNLVLVSRRGPAASGAAELVAQLTAYGAEVSLQAC 591 Query: 57 DISKLDAFDHVFQKHGKD---IKIVLHTASPFCFDITDS-----ERDLLIPAVNGVKGIL 108 D++ + V D + V+H A +++S +L P V+G + +L Sbjct: 592 DVADRETLAKVL-ASIPDEHPLTAVVHAAGVLDDGVSESLTVERLDQVLRPKVDGARNLL 650 Query: 109 HSIKKYAADSVERVVLTSSYAAVFDMA 135 I A +VL SS + V Sbjct: 651 ELIDPDVA-----LVLFSSVSGVLGSG 672 >1UZM-A nrPDB Length = 247 Score = 43.0 bits (99), Expect = 2e-04, Method: Composition-based stats. Identities = 23/145 (15%), Positives = 51/145 (35%), Gaps = 20/145 (13%) Query: 2 SVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKL 61 SV V+G N I I L + +KV + R + L V D++ Sbjct: 17 SVLVTGGNRGIGLAIAQRLAADGHKVAVTHRGSGAPKGL-----------FGVEVDVTDS 65 Query: 62 DAFDHVF---QKHGKDIKIVLHTASPFCFD-----ITDSERDLLIPAVNGVKGILHSI-K 112 DA D F ++H +++++ A + ++ + G + + Sbjct: 66 DAVDRAFTAVEEHQGPVEVLVSNAGLSADAFLMRMTEEKFEKVINANLTGAFRVAQRASR 125 Query: 113 KYAADSVERVVLTSSYAAVFDMAKE 137 + R++ S + ++ + + Sbjct: 126 SMQRNKFGRMIFIGSVSGLWGIGNQ 150 >3RFT-A nrPDB Length = 267 Score = 42.2 bits (97), Expect = 4e-04, Method: Composition-based stats. Identities = 24/181 (13%), Positives = 54/181 (29%), Gaps = 32/181 (17%) Query: 2 SVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKL 61 + V+GA G + + + + L + +L+ P V D++ Sbjct: 5 RLLVTGAAGQLGRVMRERL--------APMAEILRLADLSPLDPAGPN-EECVQCDLADA 55 Query: 62 DAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAADSVER 121 +A + + ++H + +L + G+ + + + + R Sbjct: 56 NAVNAMV----AGCDGIVHLGG---ISVEKPFEQILQGNIIGLYNLYEAARAHGQP---R 105 Query: 122 VVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAAWEFLE 181 +V SS + + P Y SK F E A + + Sbjct: 106 IVFASSNHTIGYYPQTERLGPDVPAR-------------PDGLYGVSKCFGENLARMYFD 152 Query: 182 E 182 + Sbjct: 153 K 153 >4WPG-A nrPDB Length = 289 Score = 42.2 bits (97), Expect = 4e-04, Method: Composition-based stats. Identities = 37/181 (20%), Positives = 61/181 (33%), Gaps = 41/181 (22%) Query: 3 VFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKLD 62 + ++G+NG + + LL + + E DI+ D Sbjct: 7 ILITGSNGQLGTELRYLLDERGVD-YVAVDVAE--------------------MDITNED 45 Query: 63 AFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVN--GVKGILHSIKKYAADSVE 120 + VF + +V H A+ D + E L A+N G + I + KY A Sbjct: 46 KVEAVFAQVKP--TLVYHCAAYTAVDAAEDEGKALNEAINVTGSENIAKACGKYGAT--- 100 Query: 121 RVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAAWEFL 180 +V S+ VFD K + + DP Y +K+ E A + Sbjct: 101 -LVYISTD-YVFDGNKPVGQEWVETDHP-----------DPKTEYGRTKRLGELAVERYA 147 Query: 181 E 181 E Sbjct: 148 E 148 >1BDB-A nrPDB Length = 277 Score = 41.8 bits (96), Expect = 4e-04, Method: Composition-based stats. Identities = 26/147 (17%), Positives = 50/147 (34%), Gaps = 16/147 (10%) Query: 2 SVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKL 61 +V ++G + + +VD + E KV +S E L E ++ + +V D+ L Sbjct: 7 AVLITGGASGLGRALVDRFVAEGAKVAVLDKSAE---RLAELETDHGDNVLGIVGDVRSL 63 Query: 62 DAFDHVFQKHG---KDIKIVLHTASPFCFDIT--DSERDLLIPA--------VNGVKGIL 108 + + I ++ A + + D + L A V G + Sbjct: 64 EDQKQAASRCVARFGKIDTLIPNAGIWDYSTALVDLPEESLDAAFDEVFHINVKGYIHAV 123 Query: 109 HSIKKYAADSVERVVLTSSYAAVFDMA 135 + S V+ T S A + Sbjct: 124 KACLPALVASRGNVIFTISNAGFYPNG 150 >4B4O-A nrPDB Length = 298 Score = 41.0 bits (94), Expect = 8e-04, Method: Composition-based stats. Identities = 34/284 (11%), Positives = 73/284 (25%), Gaps = 57/284 (20%) Query: 1 MSVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISK 60 M V V G GFI + LL ++V +R Sbjct: 1 MRVLVGGGTGFIGTALTQLLNARGHEVTLVSRKPGPGR---------------------- 38 Query: 61 LDAFDHVFQKHGKDIKIVLHTA-----SPFCFDITDSERDLLIPAVNGVKGILHSIKKYA 115 +D + ++ A +P ++++L + + + +I K Sbjct: 39 -ITWDELAASGLPSCDAAVNLAGENILNPLRRWNETFQKEVLGSRLETTQLLAKAITKAP 97 Query: 116 ADSVERVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKA 175 V++T + + ++E+S ++ + ++ Sbjct: 98 QPPKAWVLVT---GVAYYQPSLTAE---YDEDS-PGGDFDFFSNLVTKWEAAARL----- 145 Query: 176 AWEFLEENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLSPEDKIPEL 235 V V G + L+ + L Sbjct: 146 ---------PGDSTRQVVVRSGVVLG------RGGGAMGH--MLLPFRLGLGGPIGSGHQ 188 Query: 236 FGGYIDVRDVAKAHLVAFQKRETIGQRLIVSEARFTMQDVLDIL 279 F +I + D+A A + G V+ + T + Sbjct: 189 FFPWIHIGDLAGILTHALEANHVHGVLNGVAPSSATNAEFAQTF 232 >3PPI-A nrPDB Length = 281 Score = 40.7 bits (93), Expect = 8e-04, Method: Composition-based stats. Identities = 32/145 (22%), Positives = 51/145 (35%), Gaps = 17/145 (11%) Query: 2 SVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKF-SMEVVPDISK 60 S VSG G + + V L + V+ + + EK + L + GN +F S V + S Sbjct: 32 SAIVSGGAGGLGEATVRRLHADGLGVVIADLAAEKGKALADELGNRAEFVSTNVTSEDSV 91 Query: 61 LDAFDHVFQKHGKDIKIVLH----TASPFCFDITDSER-----DLLIPAVNGVKGILHSI 111 L A + Q +V H A + +NG + + Sbjct: 92 LAAIEAANQLGRLRYAVVAHGGFGVAQRIVQRDGSPADMGGFTKTIDLYLNGTYNVARLV 151 Query: 112 KKYAADSVER-------VVLTSSYA 129 A + R +VLT+S A Sbjct: 152 AASIAAAEPRENGERGALVLTASIA 176 >6CI9-A nrPDB Length = 259 Score = 39.9 bits (91), Expect = 0.001, Method: Composition-based stats. Identities = 27/137 (19%), Positives = 47/137 (34%), Gaps = 11/137 (8%) Query: 2 SVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKL 61 S V+G + I + I + V+ + R+Q+ + V D++ Sbjct: 11 SAIVTGGSKGIGRGIAETFANAGVDVVITGRNQDDLDRTVADLSGTRGKVTAVRADVTDP 70 Query: 62 D----AFDHVFQKHGKDIKIVLHTASPFCFD-----ITDSERDLLIPAVNGVKGILHS-I 111 + +HG + IV A F D +L G I+ + + Sbjct: 71 EDARRTVAETVSRHG-GLDIVCANAGIFPSGRLEDLTPDDIEQVLGVNFKGTVYIVQAAL 129 Query: 112 KKYAADSVERVVLTSSY 128 + A RVV+TSS Sbjct: 130 QALTASGHGRVVVTSSI 146 >5CDY-A nrPDB Length = 244 Score = 39.5 bits (90), Expect = 0.002, Method: Composition-based stats. Identities = 30/138 (21%), Positives = 60/138 (43%), Gaps = 6/138 (4%) Query: 4 FVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKLDA 63 V+GA+ I + I +LL++ VIG+A S++ AE ++ G N K M V D + +D Sbjct: 9 LVTGASRGIGRAIAELLVERGACVIGTATSEKGAEAISAYLGENGKGLMLNVVDPTSIDT 68 Query: 64 FDHVFQKHGKDIKIVLH----TASPFCFDITDSE-RDLLIPAVNGVKGILHSI-KKYAAD 117 + ++ I+++ T + D E +D++ + V + ++ + Sbjct: 69 VLATIRAEFGEVDILVNNAGITRDNLLMRMKDDEWQDIIDTNLTSVFRLSKAVMRAMMKK 128 Query: 118 SVERVVLTSSYAAVFDMA 135 R++ S A Sbjct: 129 RFGRIITIGSVVGTMGNA 146 >2NM0-A nrPDB Length = 253 Score = 39.5 bits (90), Expect = 0.002, Method: Composition-based stats. Identities = 28/142 (19%), Positives = 43/142 (30%), Gaps = 22/142 (15%) Query: 2 SVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISK- 60 SV V+G N I I KV + RS G P+ + V DI+ Sbjct: 23 SVLVTGGNRGIGLAIARAFADAGDKVAITYRS-----------GEPPEGFLAVKCDITDT 71 Query: 61 ---LDAFDHVFQKHGK-----DIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSI- 111 A+ + + HG V D ++ + G ++ Sbjct: 72 EQVEQAYKEIEETHGPVEVLIANAGVTKDQLLMRMSEEDF-TSVVETNLTGTFRVVKRAN 130 Query: 112 KKYAADSVERVVLTSSYAAVFD 133 + RVVL SS + Sbjct: 131 RAMLRAKKGRVVLISSVVGLLG 152 >1Q7C-A nrPDB Length = 244 Score = 39.5 bits (90), Expect = 0.002, Method: Composition-based stats. Identities = 41/247 (16%), Positives = 92/247 (37%), Gaps = 26/247 (10%) Query: 4 FVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKLDA 63 V+GA+ I + I + L KVIG+A S+ A+ +++ G N K M V D + +++ Sbjct: 9 LVTGASRGIGRAIAETLAARGAKVIGTATSENGAQAISDYLGANGKGLMLNVTDPASIES 68 Query: 64 FDHVFQKHGKDIKIVLH----TASPFCFDITDSE-RDLLIPAVNGVKGILHSIKKYAADS 118 + ++ I+++ T + D E D++ ++ V + ++ + Sbjct: 69 VLEKIRAEFGEVDILVNNAGITRDNLLMRMKDEEWNDIIETNLSSVFRLSKAVMRAMMKK 128 Query: 119 VE-RVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAAW 177 R++ S A + + ++ + SK A + A Sbjct: 129 RHGRIITIGSVVGTMGNG--------------GQANFAAAKAGLI---GFSKSLAREVAS 171 Query: 178 EFLEENRDSVKFELTAVNPVYV--FGPQMFDKDVKKHLNTSCELVNSLMHLSPEDKIPEL 235 + N + F T + + + L + E+ N++ L+ ++ + Sbjct: 172 RGITVNVVAPGFIETDMTRALSDDQRAGILAQVPAGRLGGAQEIANAVAFLASDEA-AYI 230 Query: 236 FGGYIDV 242 G + V Sbjct: 231 TGETLHV 237 >3RSH-A nrPDB Length = 251 Score = 39.1 bits (89), Expect = 0.003, Method: Composition-based stats. Identities = 25/138 (18%), Positives = 57/138 (41%), Gaps = 6/138 (4%) Query: 4 FVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKLDA 63 V+GA+ I + I +LL + KVIG+A S+ A+ +++ G+N K V + ++A Sbjct: 16 LVTGASRGIGKAIAELLAERGAKVIGTATSESGAQAISDYLGDNGKGMALNVTNPESIEA 75 Query: 64 FDHVFQKHGKDIKIVLHTA-----SPFCFDITDSERDLLIPAVNGVKGILHSIKKYAADS 118 + I+++ A + + D++ + + + ++ + Sbjct: 76 VLKAITDEFGGVDILVNNAGITRDNLLMRMKEEEWSDIMETNLTSIFRLSKAVLRGMMKK 135 Query: 119 VE-RVVLTSSYAAVFDMA 135 + R++ S A Sbjct: 136 RQGRIINVGSVVGTMGNA 153 >3OSU-A nrPDB Length = 246 Score = 38.3 bits (87), Expect = 0.004, Method: Composition-based stats. Identities = 29/148 (19%), Positives = 60/148 (40%), Gaps = 11/148 (7%) Query: 2 SVFVSGANGFIAQHIVDLLLKEDYKVIGSAR-SQEKAENLTEAFGNNPKFSMEVVPDISK 60 S V+GA+ I + I L +E Y V + S+EKAE + E S + +++ Sbjct: 6 SALVTGASRGIGRSIALQLAEEGYNVAVNYAGSKEKAEAVVEEIKAKGVDSFAIQANVAD 65 Query: 61 LDAFDHVFQ---KHGKDIKIVLHTASPFC--FDITDSERDLLIPAVNGVKGILHSIKKYA 115 D + + + ++++ A + E++ +KG+ + I+K Sbjct: 66 ADEVKAMIKEVVSQFGSLDVLVNNAGITRDNLLMRMKEQEWDDVIDTNLKGVFNCIQKAT 125 Query: 116 ADSVER-----VVLTSSYAAVFDMAKEN 138 + + + L+S AV + + N Sbjct: 126 PQMLRQRSGAIINLSSVVGAVGNPGQAN 153 >2DKN-A nrPDB Length = 255 Score = 37.2 bits (84), Expect = 0.011, Method: Composition-based stats. Identities = 43/225 (19%), Positives = 64/225 (28%), Gaps = 29/225 (12%) Query: 1 MSVF-VSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDIS 59 MSV ++G+ I + +LL + + VIG R Q E G Sbjct: 1 MSVIAITGSASGIGAALKELLARAGHTVIGIDRGQADIEADLSTPGGR------------ 48 Query: 60 KLDAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVN--GVKGILHSIKKYAA- 116 A V + G + ++ A L+ AVN GV +L + + + Sbjct: 49 -ETAVAAVLDRCGGVLDGLVCCAGVGVTAANSG----LVVAVNYFGVSALLDGLAEALSR 103 Query: 117 -DSVERVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKA 175 V++ S A A+ + Q AY GSK A Sbjct: 104 GQQPAAVIVGSIAATQPGAAELPMVEAMLAGDEARAIELAEQQGQTHLAYAGSKY----A 159 Query: 176 AWEFLEENRDSV---KFELTAVNPVYVFGPQMFDKDVKKHLNTSC 217 N L V P V P + S Sbjct: 160 VTCLARRNVVDWAGRGVRLNVVAPGAVETPLLQASKADPRYGEST 204 >5F5N-A nrPDB Length = 289 Score = 37.2 bits (84), Expect = 0.012, Method: Composition-based stats. Identities = 25/162 (15%), Positives = 39/162 (24%), Gaps = 24/162 (14%) Query: 2 SVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKL 61 ++ V+GA G V LL V R A V D++ Sbjct: 3 TILVTGATGTQGGATVRALLARGRPVRALVRDPGTDAARALAAAG----VSLVTGDLNDQ 58 Query: 62 DAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAADSVER 121 + D+ V + +E ++ AA V Sbjct: 59 ASLRAAM----ADVHGVFSVQTFMTPGGLGAE----------LRQGRAVADAAAATGVRH 104 Query: 122 VVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVN 163 VV +S A + + E W P Sbjct: 105 VVYSSVGGA------DRASGVPHFETKWTIERHLRSLGVPTT 140 >5ILO-A nrPDB Length = 271 Score = 36.8 bits (83), Expect = 0.013, Method: Composition-based stats. Identities = 21/97 (21%), Positives = 41/97 (42%), Gaps = 6/97 (6%) Query: 5 VSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVP-DISKLDA 63 V+G G I + LL + Q+ E + +P S+ ++ D++ Sbjct: 20 VTGGAGGIGLQVSKQLLAAGAAKVAIIDLQDNLEEFVKLRAAHPTQSVMIIKMDVANKKG 79 Query: 64 FDHVFQKHGK---DIKIVLHTASPFCFDITDSERDLL 97 + +++ K +I IV++ A F+ D +R LL Sbjct: 80 VEATYEEIAKTFGNIDIVVNVAGI--FNDKDVQRTLL 114 >1HE4-A nrPDB Length = 206 Score = 36.4 bits (82), Expect = 0.018, Method: Composition-based stats. Identities = 23/147 (15%), Positives = 48/147 (32%), Gaps = 19/147 (12%) Query: 3 VFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKLD 62 + + GA G + ++ Y+V R + P+ + VV D+ + Sbjct: 6 IAIFGATGQTGLTTLAQAVQAGYEVTVLVRDSSR------LPSEGPRPAHVVVGDVLQAA 59 Query: 63 AFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAADSVERV 122 D V+ + R+ L P +G + + A V++V Sbjct: 60 DVDKTV----AGQDAVI---------VLLGTRNDLSPTTVMSEGARNIVAAMKAHGVDKV 106 Query: 123 VLTSSYAAVFDMAKENDKSLTFNEESW 149 V +S ++D K + ++ Sbjct: 107 VACTSAFLLWDPTKVPPRLQAVTDDHI 133 >5ITV-A nrPDB Length = 255 Score = 36.0 bits (81), Expect = 0.024, Method: Composition-based stats. Identities = 36/249 (14%), Positives = 78/249 (31%), Gaps = 43/249 (17%) Query: 2 SVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKL 61 +V ++G I V L + V+ + + + E + NN + V DI+ Sbjct: 9 TVLITGGASGIGYAAVQAFLGQQANVVVADIDEAQGEAMVRKE-NNDRLHF-VQTDITDE 66 Query: 62 DAFDHVFQKHG---KDIKIVLHTA-----SPFCFDITDSERDLLIPAVNGV-KGILHSIK 112 A H + + ++++ A +P +L + G+ H++K Sbjct: 67 AACQHAVESAVHTFGGLDVLINNAGIEIVAPIHEMELSDWNKVLQVNLTGMFLMSKHALK 126 Query: 113 KYAADSVERVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFA 172 A ++ T S + W + V + Sbjct: 127 HMLAAGKGNIINTCSVGGLVA---------------WPDIPAYNASKGGVL------QLT 165 Query: 173 EKAAWEFLEENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCEL------VNSLMHL 226 + A ++ + + V P + P ++ + T E+ VN L+ L Sbjct: 166 KSMAVDYAKHQ-----IRVNCVCPGIIDTPLNEKSFLENNEGTLEEIKKEKAKVNPLLRL 220 Query: 227 SPEDKIPEL 235 ++I + Sbjct: 221 GKPEEIANV 229 >3LYL-A nrPDB Length = 247 Score = 36.0 bits (81), Expect = 0.025, Method: Composition-based stats. Identities = 24/144 (16%), Positives = 51/144 (35%), Gaps = 9/144 (6%) Query: 4 FVSGANGFIAQHIVDLLLKEDYKVIGSARSQ---EKAENLTEAFGNNPKFSMEVVPDISK 60 V+GA+ I + L + V+G+A SQ EK EN + G + + + DI Sbjct: 9 LVTGASRGIGFEVAHALASKGATVVGTATSQASAEKFENSMKEKGFKARGLVLNISDIES 68 Query: 61 LDAFDHVFQKHGKDIKIVLHTA-----SPFCFDITDSERDLLIPAVNGVKGILHSIKKYA 115 + F + I I+++ A + D + ++ ++ + + + Sbjct: 69 IQNFFAEIKAENLAIDILVNNAGITRDNLMMRMSEDEWQSVINTNLSSIFRMSKECVRGM 128 Query: 116 ADSV-ERVVLTSSYAAVFDMAKEN 138 R++ S + Sbjct: 129 MKKRWGRIISIGSVVGSAGNPGQT 152 >1QYC-A nrPDB Length = 308 Score = 36.0 bits (81), Expect = 0.025, Method: Composition-based stats. Identities = 26/174 (14%), Positives = 51/174 (29%), Gaps = 25/174 (14%) Query: 2 SVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTE---AFGNNPKFSMEVVPDI 58 + + GA G+I +H+ L + R + N + + V I Sbjct: 6 RILLIGATGYIGRHVAKASLDLGHPTFLLVRESTASSNSEKAQLLESFKASGANIVHGSI 65 Query: 59 SKLDAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAADS 118 + K++ +V+ T + I+ +IK+ + Sbjct: 66 DDHASLVEAV----KNVDVVISTVGSLQIESQ--------------VNIIKAIKE--VGT 105 Query: 119 VERVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFA 172 V+R S + D + + + E + P Y S FA Sbjct: 106 VKRF-FPSEFGNDVDNVHAVEPAKSVFEVKAKVRRAIEAEGIPYT-YVSSNCFA 157 >2GGS-A nrPDB Length = 273 Score = 35.6 bits (80), Expect = 0.031, Method: Composition-based stats. Identities = 56/327 (17%), Positives = 111/327 (33%), Gaps = 58/327 (17%) Query: 1 MSVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISK 60 M ++GA+G + + LL + ++VI S E + P+ ++ Sbjct: 1 MRTLITGASGQLGIELSRLLSER-HEVIKVYNSSEIQGGYKLDLTDFPRLEDFIIK---- 55 Query: 61 LDAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAADSVE 120 K ++++ A+ D + E++ + + H ++ A ++ Sbjct: 56 ------------KRPDVIINAAAMTDVDKCEIEKE--KAYKINAEAVRHIVR--AGKVID 99 Query: 121 RVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAAWEFL 180 ++ S VFD K N K +P+N Y SK E A + Sbjct: 100 SYIVHISTDYVFDGEKGNYKEEDIP--------------NPINYYGLSKLLGETFALQD- 144 Query: 181 EENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLSPEDKIPELFGGYI 240 + + +F + F V K L + + SP I Sbjct: 145 ---------DSLIIRTSGIFRNKGFPIYVYKTLKEGKTVFAFKGYYSP-----------I 184 Query: 241 DVRDVAKAHLVAFQKRETIGQRLIVSEARFTMQDVLDILNEDFPVLKGNIPVGKPGSGAT 300 R +A A L + R+T + V+ R + ++ + E F + V + Sbjct: 185 SARKLASAILELLELRKT--GIIHVAGERISRFELALKIKEKFNLPGEVKEVDEVRGWIA 242 Query: 301 HNTLGATLDNKKSKKLLGFKFRNLKET 327 ++LD+ +++K+L F L Sbjct: 243 KRPYDSSLDSSRARKILSTDFYTLDLD 269 >3UN1-A nrPDB Length = 260 Score = 35.3 bits (79), Expect = 0.041, Method: Composition-based stats. Identities = 25/124 (20%), Positives = 45/124 (36%), Gaps = 17/124 (13%) Query: 3 VFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKLD 62 V ++GA+ I +V +Y+V+ ++RS + + + P V DISK + Sbjct: 31 VVITGASQGIGAGLVRAYRDRNYRVVATSRSIKPSAD--------PDIHT-VAGDISKPE 81 Query: 63 AFDHV----FQKHGKDIKIV----LHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKY 114 D + ++ G+ +V + A PF + L V G I Sbjct: 82 TADRIVREGIERFGRIDSLVNNAGVFLAKPFVEMTQEDYDHNLGVNVAGFFHITQRAAAE 141 Query: 115 AADS 118 Sbjct: 142 MLKQ 145 >5LCX-A nrPDB Length = 316 Score = 35.3 bits (79), Expect = 0.042, Method: Composition-based stats. Identities = 17/86 (19%), Positives = 35/86 (40%), Gaps = 7/86 (8%) Query: 4 FVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFG-------NNPKFSMEVVP 56 V+GAN I I L ++ VI ++R++++ + N F V Sbjct: 11 LVTGANKGIGFEICRQLAEKGIIVILTSRNEKRGLEARQKLLKELNVSENRLVFHQLDVT 70 Query: 57 DISKLDAFDHVFQKHGKDIKIVLHTA 82 D++ + A + + I+++ A Sbjct: 71 DLASVAAVAVFIKSKFGKLDILVNNA 96 >5GXF-A nrPDB Length = 330 Score = 34.9 bits (78), Expect = 0.048, Method: Composition-based stats. Identities = 12/41 (29%), Positives = 17/41 (41%) Query: 3 VFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEA 43 V V+GA G + +L Y+V E A+ LT Sbjct: 153 VLVTGAAGGVGSVATAILAHLGYEVAAVTGRPETADYLTSL 193 >4IIV-A nrPDB Length = 267 Score = 34.9 bits (78), Expect = 0.049, Method: Composition-based stats. Identities = 20/150 (13%), Positives = 45/150 (30%), Gaps = 23/150 (15%) Query: 2 SVFVSGANGFIAQHIVDLLLKEDY---------------KVIGSARSQEKAENLTEAFGN 46 SV V+GA+ I + I L + + + + L+ N Sbjct: 28 SVLVTGASKGIGRAIARQLAADGFNIGVHYHRDAAGAQETLNAIVANGGNGRLLSFDVAN 87 Query: 47 NPKFSMEVVPDISKLDAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKG 106 + + +I++ A+ V G S D ++ ++ Sbjct: 88 REQCREVLEHEIAQHGAWYGVVSNAGIARDAAFPALS------NDDWDAVIHTNLDSFYN 141 Query: 107 ILHSIKKYAADSVE--RVVLTSSYAAVFDM 134 ++ + + R++ SS + V Sbjct: 142 VIQPCIMPMIGARQGGRIITLSSVSGVMGN 171 >1CYD-A nrPDB Length = 244 Score = 34.9 bits (78), Expect = 0.054, Method: Composition-based stats. Identities = 46/259 (17%), Positives = 73/259 (28%), Gaps = 37/259 (14%) Query: 1 MSVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISK 60 + V+GA I + V L KV+ R +L P V D+ Sbjct: 8 LRALVTGAGKGIGRDTVKALHASGAKVVAVTR---TNSDLVSLAKECPGIEPVCV-DLGD 63 Query: 61 LDAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAADSVE 120 DA + G + ++++ A+ ++ P + K Sbjct: 64 WDATEKALGGIGP-VDLLVNNAALV----------IMQPFLEVTKEAFDRSFSVNL---- 108 Query: 121 RVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAAWEFL 180 R V S DM N S + Y S K A + + Sbjct: 109 RSVFQVSQMVARDMINRGVPGSIVNVSS----MVAHVTFPNLITYS-STKGAMTMLTKAM 163 Query: 181 EENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLSPEDKIPELFGGYI 240 K + +VNP V D+ K ++ E L P K + Sbjct: 164 AMELGPHKIRVNSVNPTVVL------TDMGKKVSADPEFARKLKERHPLRK-------FA 210 Query: 241 DVRDVAKAHLVAFQKRETI 259 +V DV + L R Sbjct: 211 EVEDVVNSILFLLSDRSAS 229 >1GFS-A nrPDB Length = 321 Score = 34.9 bits (78), Expect = 0.055, Method: Composition-based stats. Identities = 43/299 (14%), Positives = 93/299 (31%), Gaps = 60/299 (20%) Query: 2 SVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKL 61 VF++G G + I L + V R++++ L V D Sbjct: 5 RVFIAGHRGMVGSAIRRQLEQRG-DVELVLRTRDELNLLDSR----------AVHDFFAS 53 Query: 62 DAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAADSVER 121 + D V+ K IV + P F ++++I + + I + V + Sbjct: 54 ERIDQVYLAAAKVGGIVANNTYPADF----IYQNMMIES--------NIIHAAHQNDVNK 101 Query: 122 VVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVN-AYCGSKKFAEKAAWEFL 180 ++ S + ++ E +P N Y A+ A + Sbjct: 102 LLFLGS-SCIY----PKLAKQPMAES-----ELLQGTLEPTNEPYA----IAKIAGIKLC 147 Query: 181 EENRDSVKFELTAVNPVYVFGPQMFDKDVKKHL---------NTSCELVNSLMHLSPEDK 231 E + +V P ++GP H+ + + ++ Sbjct: 148 ESYNRQYGRDYRSVMPTNLYGPHDNFHPSNSHVIPALLRRFHEATAQNAPDVVVWGSGTP 207 Query: 232 IPELFGGYIDVRDVA--------KAHLVAFQKRETIGQRLIVSEAR-FTMQDVLDILNE 281 + E ++ V D+A AH V + + + + V T++++ + + Sbjct: 208 MRE----FLHVDDMAAASIHVMELAHEVWLENTQPMLSHINVGTGVDCTIRELAQTIAK 262 >2J3K-A nrPDB Length = 345 Score = 34.9 bits (78), Expect = 0.057, Method: Composition-based stats. Identities = 19/58 (32%), Positives = 32/58 (55%) Query: 2 SVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDIS 59 +V+VS A+G + Q + L V+GSA S+EK + L FG + F+ + D++ Sbjct: 158 TVYVSAASGAVGQLVGQLAKMMGCYVVGSAGSKEKVDLLKTKFGFDDAFNYKEESDLT 215 >4IIN-A nrPDB Length = 271 Score = 34.5 bits (77), Expect = 0.062, Method: Composition-based stats. Identities = 14/68 (20%), Positives = 24/68 (35%), Gaps = 1/68 (1%) Query: 3 VFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVP-DISKL 61 V ++GA+ I I L KV + RS + + + + V+ D + Sbjct: 32 VLITGASKGIGAEIAKTLASMGLKVWINYRSNAEVADALKNELEEKGYKAAVIKFDAASE 91 Query: 62 DAFDHVFQ 69 F Q Sbjct: 92 SDFIEAIQ 99 >3F9I-A nrPDB Length = 249 Score = 34.5 bits (77), Expect = 0.072, Method: Composition-based stats. Identities = 31/139 (22%), Positives = 57/139 (41%), Gaps = 8/139 (5%) Query: 2 SVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKL 61 + ++GA+ I I LL K KVI S ++EK ++L A +N V +++ Sbjct: 16 TSLITGASSGIGSAIARLLHKLGSKVIISGSNEEKLKSLGNALKDN---YTIEVCNLANK 72 Query: 62 DAFDHVFQKHGKDIKIVLH---TASPFCFDITDSERDLLIPAVNGVKGILH--SIKKYAA 116 + ++ K +V + T+ + D + D +I IL+ +IKK Sbjct: 73 EECSNLISKTSNLDILVCNAGITSDTLAIRMKDQDFDKVIDINLKANFILNREAIKKMIQ 132 Query: 117 DSVERVVLTSSYAAVFDMA 135 R++ SS + Sbjct: 133 KRYGRIINISSIVGIAGNP 151 >1AE1-A nrPDB Length = 273 Score = 33.7 bits (75), Expect = 0.11, Method: Composition-based stats. Identities = 37/241 (15%), Positives = 88/241 (36%), Gaps = 31/241 (12%) Query: 2 SVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKL 61 + V+G + I IV+ L +V +R++++ + E + V D+ Sbjct: 23 TALVTGGSKGIGYAIVEELAGLGARVYTCSRNEKELDECLEIWREKGLNVEGSVCDLLSR 82 Query: 62 DAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAADSVER 121 D + Q V H + D + ++L VN ++H K + Sbjct: 83 TERDKLMQ-------TVAH--------VFDGKLNIL---VNNAGVVIHKEAKDFTEKDYN 124 Query: 122 VVLTSSYAAVFDMAKENDKSLTFNEES---WNPATWESCQSDPVNAYCGSK----KFAEK 174 +++ +++ A + +++ L ++ + + V+ Y SK + + Sbjct: 125 IIMGTNFEAAYHLSQIAYPLLKASQNGNVIFLSSIAGFSALPSVSLYSASKGAINQMTKS 184 Query: 175 AAWEFLEENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLSPEDKIPE 234 A E+ ++N + +V P + P + +KK+ + E+ N ++ Sbjct: 185 LACEWAKDN-----IRVNSVAPGVILTPLVETA-IKKNPHQKEEIDNFIVKTPMGRAGKP 238 Query: 235 L 235 Sbjct: 239 Q 239 >4CQM-B nrPDB Length = 244 Score = 33.7 bits (75), Expect = 0.11, Method: Composition-based stats. Identities = 35/257 (13%), Positives = 95/257 (36%), Gaps = 31/257 (12%) Query: 3 VF-VSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLT-EAFGNNPKFSMEVVPDISK 60 V V G + I + + L+ ++ Y++ AR+ E A+ + G++ FS +V + Sbjct: 11 VCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHDV 70 Query: 61 LDAFDHVFQKHGKDIKIVLHTASPFC--FDITDSERDLLIPAVNGVKGILHSIKKYAADS 118 + F+ +KH + +++ A + D++ + G + + K Sbjct: 71 QNTFEE-LEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRTM 129 Query: 119 VER----VVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEK 174 +++ +V + ++ + + +S+ S + + S+ A++ Sbjct: 130 IQQQGGSIV---NVGSIVGLKGNSGQSVY------------SASKGGLVGF--SRALAKE 172 Query: 175 AAWEFLEENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLSPEDKIPE 234 A + + N + F T + + + + E+ ++++ L Sbjct: 173 VARKKIRVNVVAPGFVHTDMTK-DLKEEHLKKNIPLGRFGETIEVAHAVVFLLES----P 227 Query: 235 LFGGYIDVRDVAKAHLV 251 G++ V D ++ Sbjct: 228 YITGHVLVVDGGLQLIL 244 >2Q4B-A nrPDB Length = 253 Score = 33.7 bits (75), Expect = 0.13, Method: Composition-based stats. Identities = 31/148 (20%), Positives = 50/148 (33%), Gaps = 20/148 (13%) Query: 2 SVFVSGANGFIAQHIVDLLLK--EDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDIS 59 +V V+GA+G Q + L + + + G RS + E G + DI+ Sbjct: 6 TVLVTGASGRTGQIVYKKLKEGSDKFVAKGLVRSAQG----KEKIGGEADV---FIGDIT 58 Query: 60 KLDAFDHVFQKHGKDIKIVLHTASPFCFDITDSE---------RDLLIPAVNGVKGILHS 110 D+ + FQ G D ++L +A P D D P G + Sbjct: 59 DADSINPAFQ--GIDALVILTSAVPKMKPGFDPTKGGRPEFIFEDGQYPEQVDWIGQKNQ 116 Query: 111 IKKYAADSVERVVLTSSYAAVFDMAKEN 138 I V+ +V+ S N Sbjct: 117 IDAAKVAGVKHIVVVGSMGGTNPDHPLN 144 >4KTT-E nrPDB Length = 327 Score = 33.3 bits (74), Expect = 0.16, Method: Composition-based stats. Identities = 55/339 (16%), Positives = 105/339 (30%), Gaps = 57/339 (16%) Query: 2 SVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKL 61 V V+GA G + + + + ++ +G PKF ++ Sbjct: 23 RVLVTGATGLLGRAVHKEFQQNNWHAVGC-----------GFRRARPKFEQV---NLLDS 68 Query: 62 DAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAADSVER 121 +A H+ + ++H A+ D+ +++ D A ++ K AA Sbjct: 69 NAVHHIIHDFQPHV--IVHCAAERRPDVVENQPDA---ASQLNVDASGNLAKEAAAVGAF 123 Query: 122 VVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAAWEFLE 181 ++ SS F+ NP E P+N Y +K EKA Sbjct: 124 LIYISS-------------DYVFDGT--NPPYREEDIPAPLNLYGKTKLDGEKAVL---- 164 Query: 182 ENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLSPEDKIPELFGGY-- 239 EN + +V+K ++ ++ + S + + + Sbjct: 165 ENNLGAAVLRIPILY----------GEVEKLEESAVTVMFDKVQFSNKSANMDHWQQRFP 214 Query: 240 IDVRDVAKAHLVAFQK----RETIGQRLIVSEARFTMQDVLDILNEDF--PVLKGNIPVG 293 V+DVA +K G + T ++ + + F P Sbjct: 215 THVKDVATVCRQLAEKRMLDPSIKGTFHWSGNEQMTKYEMACAIADAFNLPSSHLRPITD 274 Query: 294 KPGSGATHNTLGATLDNKKSKKLLGFKFRNLKETIDDTA 332 P GA A LD K + L + + I ++ Sbjct: 275 SPVLGAQRPR-NAQLDCSKLETLGIGQRTPFRIGIKESL 312 >2QYS-A nrPDB Length = 318 Score = 33.3 bits (74), Expect = 0.16, Method: Composition-based stats. Identities = 13/77 (16%), Positives = 30/77 (38%), Gaps = 6/77 (7%) Query: 3 VFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKLD 62 + + G G+I H+V LK + R L + F + ++ V ++ + + Sbjct: 14 ILIFGGTGYIGNHMVKGSLKLGHPTYVFTRPNSSKTTLLDEFQSLG--AIIVKGELDEHE 71 Query: 63 AFDHVFQKHGKDIKIVL 79 + K + +V+ Sbjct: 72 KLVELM----KKVDVVI 84 >3SC6-A nrPDB Length = 287 Score = 32.9 bits (73), Expect = 0.18, Method: Composition-based stats. Identities = 51/318 (16%), Positives = 99/318 (31%), Gaps = 57/318 (17%) Query: 2 SVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKL 61 V ++GANG + + + + L E+Y + + L DI+ + Sbjct: 7 RVIITGANGQLGKQLQEELNPEEYDIY-----PFDKKLL----------------DITNI 45 Query: 62 DAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAADSVER 121 V Q+ I ++H A+ D + ERDL V G + + Sbjct: 46 SQVQQVVQEIRPHI--IIHCAAYTKVDQAEKERDLA--YVINAIGARNVAVASQLVGAKL 101 Query: 122 VVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAAWEFLE 181 V +++ Y VF + ++E P+N Y SK E+ F++ Sbjct: 102 VYISTDY--VFQGDRPEG----YDEFH---------NPAPINIYGASKYAGEQ----FVK 142 Query: 182 ENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLSPEDKIPELFGGYID 241 E + V +++G K N ++ + + G Sbjct: 143 ELHNKYFI----VRTSWLYG--------KYGNNFVKTMIRLGKEREEISVVADQIGSPTY 190 Query: 242 VRDVAKAHLVAFQKRETIGQRLIVSEARFTMQDVLDILNEDFPVLKGNIPVGKPGSGATH 301 V D+ + G + + + + + + +PV GA Sbjct: 191 VADL-NVMINKLIHTSLYGTYHVSNTGSCSWFEFAKKIFSYANMKVNVLPVSTEEFGAAA 249 Query: 302 NTLGATLDNKKSKKLLGF 319 ++ +L GF Sbjct: 250 ARPKYSIFQHNMLRLNGF 267 >1DXY-A nrPDB Length = 333 Score = 32.9 bits (73), Expect = 0.20, Method: Composition-based stats. Identities = 25/121 (20%), Positives = 42/121 (34%), Gaps = 15/121 (12%) Query: 2 SVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKL 61 +V V G G I Q + L KVI K G++P F + D+ K Sbjct: 147 TVGVMG-TGHIGQVAIKLFKGFGAKVIAYDPYPMK--------GDHPDFDYVSLEDLFKQ 197 Query: 62 DAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLL---IPAVNGVKGILHSIKKYAADS 118 V H I+ H + F++ ++ P + + +L ++K Sbjct: 198 S---DVIDLHVPGIEQNTHIINEAAFNLMKPGAIVINTARPNLIDTQAMLSNLKSGKLAG 254 Query: 119 V 119 V Sbjct: 255 V 255 >2AE2-A nrPDB Length = 260 Score = 32.9 bits (73), Expect = 0.20, Method: Composition-based stats. Identities = 29/146 (19%), Positives = 51/146 (34%), Gaps = 10/146 (6%) Query: 2 SVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKL 61 + V+G + I IV+ L V +R+Q++ + + + V D+S Sbjct: 11 TALVTGGSRGIGYGIVEELASLGASVYTCSRNQKELNDCLTQWRSKGFKVEASVCDLSSR 70 Query: 62 DAFDHVF-----QKHGKDIKIVLHTASPFCFDITDS--ERDLLIPAVN-GVKGILHSIKK 113 + HGK +V + + D E LI ++N L + Sbjct: 71 SERQELMNTVANHFHGKLNILVNNAGIVIYKEAKDYTVEDYSLIMSINFEAAYHLSVLAH 130 Query: 114 YAADSVER--VVLTSSYAAVFDMAKE 137 + ER VV SS + + E Sbjct: 131 PFLKASERGNVVFISSVSGALAVPYE 156 >1V3V-A nrPDB Length = 333 Score = 32.6 bits (72), Expect = 0.23, Method: Composition-based stats. Identities = 20/79 (25%), Positives = 35/79 (44%), Gaps = 7/79 (8%) Query: 2 SVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISK- 60 +V VS A G + + + + KV+G+A S EK L + G + F+ + V + + Sbjct: 148 TVLVSAAAGAVGSVVGQIAKLKGCKVVGAAGSDEKIAYLKQ-IGFDAAFNYKTVNSLEEA 206 Query: 61 -----LDAFDHVFQKHGKD 74 D +D F G + Sbjct: 207 LKKASPDGYDCYFDNVGGE 225 >3DWF-A nrPDB Length = 276 Score = 32.6 bits (72), Expect = 0.24, Method: Composition-based stats. Identities = 25/136 (18%), Positives = 45/136 (33%), Gaps = 9/136 (6%) Query: 3 VFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKLD 62 V V+GA+ I + I L K V+ +ARS+E + + S + + Sbjct: 14 VIVTGASKGIGREIAYHLAKMGAHVVVTARSKEALQKVVARCLELGAASAHYIAGSMEDM 73 Query: 63 AFDHVFQKHGKDIKI---------VLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKK 113 F F ++ VL+ F D+ R + + + + Sbjct: 74 TFAEEFVAEAGNLMGGLDMLILNHVLYNRLTFFHGEIDNVRKSMEVNFHSFVVLSVAAMP 133 Query: 114 YAADSVERVVLTSSYA 129 S + + SS A Sbjct: 134 MLMQSQGSIAVVSSVA 149 >1HXH-A nrPDB Length = 253 Score = 32.6 bits (72), Expect = 0.24, Method: Composition-based stats. Identities = 16/79 (20%), Positives = 29/79 (36%) Query: 4 FVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKLDA 63 V+G + +V LLL E KV S ++ + L G F V + Sbjct: 10 LVTGGASGVGLEVVKLLLGEGAKVAFSDINEAAGQQLAAELGERSMFVRHDVSSEADWTL 69 Query: 64 FDHVFQKHGKDIKIVLHTA 82 Q+ + ++++ A Sbjct: 70 VMAAVQRRLGTLNVLVNNA 88 >1VL0-A nrPDB Length = 292 Score = 32.6 bits (72), Expect = 0.28, Method: Composition-based stats. Identities = 49/337 (14%), Positives = 107/337 (31%), Gaps = 68/337 (20%) Query: 1 MSVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISK 60 M + ++GANG + + I L ++ +VI ++L DI+ Sbjct: 13 MKILITGANGQLGREIQKQLKGKNVEVI-----PTDVQDL----------------DITN 51 Query: 61 LDAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAADSVE 120 + A + F + K +V++ A+ + E + G + AA SV Sbjct: 52 VLAVNKFFNE--KKPNVVINCAA--HTAVDKCEEQYDLAYKINAIGPKNL--AAAAYSVG 105 Query: 121 RVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAAWEFL 180 ++ S VFD + + F+E + P +AY +K E F+ Sbjct: 106 AEIVQISTDYVFD-GEAKEPITEFDEVN------------PQSAYGKTKLEGE----NFV 148 Query: 181 EENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLSPEDKIPELFGGYI 240 + V +++G + VK +N + + + + G Sbjct: 149 KALNPKYYI----VRTAWLYGD--GNNFVKTMINLG--KTHDELKVVHDQ-----VGTPT 195 Query: 241 DVRDVAKAHLVAFQKRETIGQRLIVSEARFTMQDV-LDILN------EDFPVLKGNIPVG 293 D+A+ L ++ + + D ++I + P P Sbjct: 196 STVDLARVVLKVIDEKNYGTFHCTC-KGICSWYDFAVEIFRLTGIDVKVTPCTTEEFPRP 254 Query: 294 KPGSGATHNTLGATLDNKKSKKLLGFKFRNLKETIDD 330 ++ + + + +++ + D Sbjct: 255 AK---RPKYSVLRNYMLELTTGDITREWKESLKEYID 288 >1O89-A nrPDB Length = 345 Score = 32.6 bits (72), Expect = 0.28, Method: Composition-based stats. Identities = 17/70 (24%), Positives = 28/70 (40%), Gaps = 5/70 (7%) Query: 3 VFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNN--PKFSMEVVPDISK 60 + V+GA+G + V LL K Y+V+ + + E L + P+ + K Sbjct: 171 IVVTGASGGVGSTAVALLHKLGYQVVAVSGRESTHEYLKSLGASRVLPRDEFAESRPLEK 230 Query: 61 L---DAFDHV 67 A D V Sbjct: 231 QVWAGAIDTV 240 >6G2J-P nrPDB Length = 377 Score = 32.6 bits (72), Expect = 0.29, Method: Composition-based stats. Identities = 28/145 (19%), Positives = 51/145 (35%), Gaps = 15/145 (10%) Query: 5 VSGANGFIAQHIVDLLLKEDYKVIGSAR-SQEKAENLTEAFGNNPKFSMEVVPDISKLDA 63 V GA GF+ +++V+ L + +VI R +L G+ + + + D D+ Sbjct: 58 VFGATGFLGRYVVNHLGRMGSQVIIPYRCDVYDIMHLR-LMGDLGQLTF-LEWDARDKDS 115 Query: 64 FDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSI-KKYAADSVERV 122 Q I ++ FD D I +I + VER Sbjct: 116 IRKAVQHSNVVINLIGREWETRNFDFEDV-----------FVNIPRAIAQASKEAGVERF 164 Query: 123 VLTSSYAAVFDMAKENDKSLTFNEE 147 + S A + ++ +S E+ Sbjct: 165 IHVSHLNASMKSSSKSLRSKAVGEK 189 >3D3W-A nrPDB Length = 244 Score = 32.2 bits (71), Expect = 0.32, Method: Composition-based stats. Identities = 37/201 (18%), Positives = 68/201 (33%), Gaps = 28/201 (13%) Query: 2 SVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLT-EAFGNNPKFSMEVVPDISK 60 V V+GA I + V L +V+ +R+Q ++L E G P V D+ Sbjct: 9 RVLVTGAGKGIGRGTVQALHATGARVVAVSRTQADLDSLVRECPGIEP-----VCVDLGD 63 Query: 61 LDAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAADSVE 120 +A + G P + ++ LL P + K + + ++ Sbjct: 64 WEATERALGSVG-----------PVDLLVNNAAVALLQPFLEVTK---EAFDRSFEVNLR 109 Query: 121 RVVLTSSYAAVFDMAKENDKSLT-FNEESWNPATWESCQSDPVNAYCGSKKFAEKAAWEF 179 V+ S A +A+ ++ + + A YC +K + + Sbjct: 110 AVIQVSQIVARGLIARGVPGAIVNVSSQCSQRAVTNHSV------YCSTKGALDM-LTKV 162 Query: 180 LEENRDSVKFELTAVNPVYVF 200 + K + AVNP V Sbjct: 163 MALELGPHKIRVNAVNPTVVM 183 >2B4Q-A nrPDB Length = 276 Score = 32.2 bits (71), Expect = 0.37, Method: Composition-based stats. Identities = 24/147 (16%), Positives = 49/147 (33%), Gaps = 14/147 (9%) Query: 4 FVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKLDA 63 V+G + I Q I LL+ +V AR E + + D+S Sbjct: 33 LVTGGSRGIGQMIAQGLLEAGARVFICARDAEACADTATRLSAYGDCQA-IPADLSSEAG 91 Query: 64 ---FDHVFQKHGKDIKIVLHTASPFCFDITDSE-----RDLLIPAVNGVKGILHSI---- 111 + + I+++ A +S ++ V V + + Sbjct: 92 ARRLAQALGELSARLDILVNNAGTSWGAALESYPVSGWEKVMQLNVTSVFSCIQQLLPLL 151 Query: 112 -KKYAADSVERVVLTSSYAAVFDMAKE 137 + +A++ RV+ S A + M ++ Sbjct: 152 RRSASAENPARVINIGSVAGISAMGEQ 178 >5TQV-A nrPDB Length = 233 Score = 32.2 bits (71), Expect = 0.37, Method: Composition-based stats. Identities = 12/78 (15%), Positives = 27/78 (34%), Gaps = 3/78 (3%) Query: 2 SVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKL 61 +V + GA+ + + V ++ + VI +AR L + ++ Sbjct: 11 TVLIVGASRGLGREFVRQYQRDGWNVIATARDDASLAALRAL---GAHAHALDITQPEQI 67 Query: 62 DAFDHVFQKHGKDIKIVL 79 A D+ +V+ Sbjct: 68 AALGWKLDGERLDVAVVV 85 >2YV2-A nrPDB Length = 297 Score = 31.8 bits (70), Expect = 0.45, Method: Composition-based stats. Identities = 16/87 (18%), Positives = 33/87 (37%), Gaps = 10/87 (11%) Query: 2 SVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKA---------ENLTEAFGNNPKFSM 52 V V G G +L+ KV+ + +++ EA +P+ + Sbjct: 15 RVLVQGITGREGSFHAKAMLEYGTKVVAGVTPGKGGSEVHGVPVYDSVKEALAEHPEINT 74 Query: 53 EVVPDISKLDAFDHVFQKHGKDIKIVL 79 +V + A D V++ I++V+ Sbjct: 75 SIVF-VPAPFAPDAVYEAVDAGIRLVV 100 >2Y05-A nrPDB Length = 328 Score = 31.8 bits (70), Expect = 0.47, Method: Composition-based stats. Identities = 18/79 (22%), Positives = 34/79 (43%), Gaps = 7/79 (8%) Query: 2 SVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISK- 60 +V V+ A G + + + + KV+G+ S EK L + G + F+ + V + + Sbjct: 143 TVMVNAAAGAVGSVVGQIAKLKGCKVVGAVGSDEKVAYLQKL-GFDVVFNYKTVESLEET 201 Query: 61 -----LDAFDHVFQKHGKD 74 D +D F G + Sbjct: 202 LKKASPDGYDCYFDNVGGE 220 >2X9N-A nrPDB Length = 288 Score = 31.4 bits (69), Expect = 0.57, Method: Composition-based stats. Identities = 18/103 (17%), Positives = 37/103 (35%), Gaps = 12/103 (11%) Query: 5 VSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVV--PDISK-- 60 V+GA I + I L + Y+V+ + +A N + + VV D++ Sbjct: 28 VTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTNSN 87 Query: 61 --LDAFDHVFQKH---GKDIKIVLHTAS---PFCFDITDSERD 95 + + + ++++ AS P D E + Sbjct: 88 VLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVQGDHEDN 130 >3GRP-A nrPDB Length = 266 Score = 31.4 bits (69), Expect = 0.59, Method: Composition-based stats. Identities = 21/144 (14%), Positives = 44/144 (30%), Gaps = 12/144 (8%) Query: 4 FVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKLDA 63 V+GA G I + I + ++G + + L E + K ++S + Sbjct: 31 LVTGATGGIGEAIARCFHAQG-AIVGL--HGTREDKLKEIAADLGKDVFVFSANLSDRKS 87 Query: 64 ---FDHVFQKHGKDIKIVLHTASP------FCFDITDSERDLLIPAVNGVKGILHSIKKY 114 V ++ + I I+++ A D + L + I Sbjct: 88 IKQLAEVAEREMEGIDILVNNAGITRDGLFVRMQDQDWDDVLAVNLTAASTLTRELIHSM 147 Query: 115 AADSVERVVLTSSYAAVFDMAKEN 138 R++ +S V + Sbjct: 148 MRRRYGRIINITSIVGVVGNPGQT 171 >4BO1-A nrPDB Length = 269 Score = 31.0 bits (68), Expect = 0.69, Method: Composition-based stats. Identities = 31/144 (21%), Positives = 56/144 (38%), Gaps = 9/144 (6%) Query: 4 FVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKLDA 63 V+GA+ I Q I L + VIG+A S AE + E N +V D+S ++ Sbjct: 31 LVTGASRGIGQAIALELGRLGAVVIGTATSASGAEKIAETLKANGVEGAGLVLDVSSDES 90 Query: 64 FD---HVFQKHGKDIKIVLH----TASPFCFDITDSE-RDLLIPAVNGVKGILHSIKKYA 115 Q+H IV++ T + D E D++ +N + + ++ + Sbjct: 91 VAATLEHIQQHLGQPLIVVNNAGITRDNLLVRMKDDEWFDVVNTNLNSLYRLSKAVLRGM 150 Query: 116 ADSV-ERVVLTSSYAAVFDMAKEN 138 + R++ S A + Sbjct: 151 TKARWGRIINIGSVVGAMGNAGQT 174 >1QYD-A nrPDB Length = 313 Score = 31.0 bits (68), Expect = 0.84, Method: Composition-based stats. Identities = 9/42 (21%), Positives = 17/42 (40%), Gaps = 1/42 (2%) Query: 2 SVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEA 43 V + G G+I + IV+ + + R E N+ + Sbjct: 6 RVLIVGGTGYIGKRIVNASISLGHPTYVLFR-PEVVSNIDKV 46 >5TZ8-A nrPDB Length = 572 Score = 30.6 bits (67), Expect = 0.87, Method: Composition-based stats. Identities = 26/129 (20%), Positives = 46/129 (35%), Gaps = 17/129 (13%) Query: 88 DITDSERDLLIPAVNGV--KGILHSIKKYAADSVE----RVVLTSSYAAVFDMAKENDKS 141 I + D+L+ + GV +G+ S+ K A V R++ T S ++ A D Sbjct: 107 FIDEHHSDVLLIKMKGVNGRGVPQSMFKETAPEVTLLNSRIIYTLSPTKIYRTALLKDND 166 Query: 142 LTFNEESWNPATWESCQSDPVNA-----------YCGSKKFAEKAAWEFLEENRDSVKFE 190 + F EE + +NA Y +K+ E + ++ Sbjct: 167 IYFPEELKSAEDQLFTMKAYLNANRISVLSDKAYYYATKREGEHMSSAYVSPEDFYEVMR 226 Query: 191 LTAVNPVYV 199 L AV + Sbjct: 227 LIAVEILNA 235 >5WQO-A nrPDB Length = 234 Score = 30.6 bits (67), Expect = 0.92, Method: Composition-based stats. Identities = 13/60 (21%), Positives = 24/60 (40%) Query: 3 VFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKLD 62 V + GA+ I + D L+ +V AR + + L + V D+++ D Sbjct: 9 VLIVGASRGIGLGLADAFLQRGAQVFAVARRPQGSPGLQALAERAGERLQAVTGDLNQHD 68 >2VCE-A nrPDB Length = 480 Score = 30.6 bits (67), Expect = 0.92, Method: Composition-based stats. Identities = 13/57 (22%), Positives = 22/57 (38%) Query: 32 RSQEKAENLTEAFGNNPKFSMEVVPDISKLDAFDHVFQKHGKDIKIVLHTASPFCFD 88 RS + + ++F + +V D+ DAFD + H TA+ F Sbjct: 92 RSNPELRKVFDSFVEGGRLPTALVVDLFGTDAFDVAVEFHVPPYIFYPTTANVLSFF 148 >4Q2R-A nrPDB Length = 381 Score = 30.6 bits (67), Expect = 0.94, Method: Composition-based stats. Identities = 13/62 (20%), Positives = 26/62 (41%) Query: 281 EDFPVLKGNIPVGKPGSGATHNTLGATLDNKKSKKLLGFKFRNLKETIDDTASQILKFEG 340 E FP + + + K G+G + + + LGF L + + D +++ E Sbjct: 306 EKFPEVLKRLRLQKRGTGGVDTAAVGGVFDVSNADRLGFSEVELVQMVVDGVKLLIEMEQ 365 Query: 341 RI 342 R+ Sbjct: 366 RL 367 >1P33-A nrPDB Length = 289 Score = 30.6 bits (67), Expect = 0.96, Method: Composition-based stats. Identities = 16/59 (27%), Positives = 22/59 (37%), Gaps = 2/59 (3%) Query: 4 FVSGANGFIAQHIVDLLLKEDYKVIGSA-RSQEKAENL-TEAFGNNPKFSMEVVPDISK 60 V+GA + I + L E Y V RS A L P ++ V D+S Sbjct: 11 LVTGAAKRLGSSIAEALHAEGYTVCLHYHRSAADASTLAATLNARRPNSAITVQADLSN 69 >2EXX-A nrPDB Length = 306 Score = 30.6 bits (67), Expect = 1.1, Method: Composition-based stats. Identities = 10/37 (27%), Positives = 15/37 (40%), Gaps = 1/37 (2%) Query: 3 VFVSGANGFIAQHIVDLLLKED-YKVIGSARSQEKAE 38 V V G G + LL++ +KV R+ K Sbjct: 14 VVVFGGTGAQGGSVARTLLEDGTFKVRVVTRNPRKKA 50 >2BKA-A nrPDB Length = 242 Score = 30.3 bits (66), Expect = 1.3, Method: Composition-based stats. Identities = 19/70 (27%), Positives = 32/70 (45%), Gaps = 4/70 (5%) Query: 2 SVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKL 61 SVF+ GA+G + ++ +L++ + + K EA+ N + V D KL Sbjct: 20 SVFILGASGETGRVLLKEILEQGLFSKVTLIGRRKLTFDEEAYKNVNQ----EVVDFEKL 75 Query: 62 DAFDHVFQKH 71 D + FQ H Sbjct: 76 DDYASAFQGH 85 >5PGZ-A nrPDB Length = 276 Score = 30.3 bits (66), Expect = 1.4, Method: Composition-based stats. Identities = 15/66 (22%), Positives = 26/66 (39%) Query: 3 VFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKLD 62 V V+GA+ I + + L K V+ +ARS+E + + S + + Sbjct: 21 VIVTGASKGIGREMAYHLSKMGAHVVLTARSEEGLQKVVSRCLELGAASAHYIAGTMEDM 80 Query: 63 AFDHVF 68 F F Sbjct: 81 TFAEQF 86 >6DKT-A nrPDB Length = 296 Score = 30.3 bits (66), Expect = 1.4, Method: Composition-based stats. Identities = 11/59 (18%), Positives = 21/59 (35%), Gaps = 9/59 (15%) Query: 14 QHIVDLLLKEDYKV---------IGSARSQEKAENLTEAFGNNPKFSMEVVPDISKLDA 63 H+++ L Y V ++ E+ +NL N K + +V I + Sbjct: 31 AHLIERLSDMGYTVEDLGDIPINREKIKNDEELKNLNSVLAGNEKLAQKVNKVIEEKKF 89 >4IQF-A nrPDB Length = 317 Score = 30.3 bits (66), Expect = 1.4, Method: Composition-based stats. Identities = 6/33 (18%), Positives = 14/33 (42%) Query: 16 IVDLLLKEDYKVIGSARSQEKAENLTEAFGNNP 48 ++ L+++ Y VIG ++ + P Sbjct: 19 VLRRLIEDGYDVIGVVTQPDRPVGRKKVLTPTP 51 >1H5Q-A nrPDB Length = 265 Score = 30.3 bits (66), Expect = 1.4, Method: Composition-based stats. Identities = 27/140 (19%), Positives = 49/140 (35%), Gaps = 11/140 (7%) Query: 2 SVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVP-DISK 60 ++ V+G N I + V RS A +TE G + D+S Sbjct: 16 TIIVTGGNRGIGLAFTRAVAAAGANVAVIYRSAADAVEVTEKVGKEFGVKTKAYQCDVSN 75 Query: 61 LDAFDHVFQKHGKD---IKIVLHTA--SPFCFDITDSERDLLIPAVNGVKGILHSIKKYA 115 D Q+ D I ++ A S + D V G+ ++ + A Sbjct: 76 TDIVTKTIQQIDADLGPISGLIANAGVSVVKPATELTHEDFAFVYDVNVFGVFNTCRAVA 135 Query: 116 ADSVER-----VVLTSSYAA 130 +++ +V+TSS ++ Sbjct: 136 KLWLQKQQKGSIVVTSSMSS 155 >5B1Y-A nrPDB Length = 270 Score = 29.9 bits (65), Expect = 1.6, Method: Composition-based stats. Identities = 15/76 (19%), Positives = 32/76 (42%), Gaps = 6/76 (7%) Query: 4 FVSGANGFIAQHIVDLLLKEDYKVIGSARS----QEKAENLTEAFGNNPKFSMEVVPDIS 59 V+G + I + V +E + V+ + +S EK G+ +++ V D+ Sbjct: 27 LVTGGSRGIGRATVLRFAREGWSVVIAYKSRADLAEKTAEEARRLGSPEAYTVRV--DVG 84 Query: 60 KLDAFDHVFQKHGKDI 75 D+ + + G+ I Sbjct: 85 DPDSVTEMSSRVGELI 100 >1VIM-A nrPDB Length = 200 Score = 29.9 bits (65), Expect = 1.6, Method: Composition-based stats. Identities = 11/29 (37%), Positives = 16/29 (55%), Gaps = 2/29 (6%) Query: 2 SVFVSGA--NGFIAQHIVDLLLKEDYKVI 28 S+FV GA +G+IA+ L+ Y V Sbjct: 49 SIFVIGAGRSGYIAKAFAMRLMHLGYTVY 77 >3PVZ-A nrPDB Length = 399 Score = 29.5 bits (64), Expect = 1.9, Method: Composition-based stats. Identities = 19/135 (14%), Positives = 41/135 (30%), Gaps = 7/135 (5%) Query: 2 SVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDI--- 58 V G G I Q + + K + + + E N+ E + + D Sbjct: 37 RFLVLGGAGSIGQAVTKEIFKRNPQKLHVVDISEN--NMVELVRDIRSSFGYINGDFQTF 94 Query: 59 -SKLDAFDH-VFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAA 116 + + ++ F K VL+ ++ L+ V +I++ Sbjct: 95 ALDIGSIEYDAFIKADGQYDYVLNLSALKHVRSEKDPFTLMRMIDVNVFNTDKTIQQSID 154 Query: 117 DSVERVVLTSSYAAV 131 ++ S+ A Sbjct: 155 AGAKKYFCVSTDKAA 169 >1YXM-A nrPDB Length = 303 Score = 29.5 bits (64), Expect = 2.0, Method: Composition-based stats. Identities = 13/45 (28%), Positives = 22/45 (48%), Gaps = 1/45 (2%) Query: 5 VSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLT-EAFGNNP 48 V+G I + IV LL+ V+ ++R E+ ++ E N P Sbjct: 23 VTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLP 67 >3V2G-A nrPDB Length = 271 Score = 29.5 bits (64), Expect = 2.2, Method: Composition-based stats. Identities = 15/105 (14%), Positives = 37/105 (35%), Gaps = 10/105 (9%) Query: 2 SVFVSGANGFIAQHIVDLLLKEDYKVIGS-ARSQEKAENLTEAFGNNPKFSMEVVPDISK 60 + FV+G + I I L E V + + E+A+ + ++ + D Sbjct: 33 TAFVTGGSRGIGAAIAKRLALEGAAVALTYVNAAERAQAVVSEIEQAGGRAVAIRADNRD 92 Query: 61 LDAFDHVFQKHGKDI---------KIVLHTASPFCFDITDSERDL 96 +A + ++ + + + H+A + D + + Sbjct: 93 AEAIEQAIRETVEALGGLDILVNSAGIWHSAPLEETTVADFDEVM 137 >4AXH-A nrPDB Length = 668 Score = 29.5 bits (64), Expect = 2.3, Method: Composition-based stats. Identities = 20/109 (18%), Positives = 36/109 (33%), Gaps = 6/109 (5%) Query: 150 NPATWESCQSDPVNAYCGSKKFAE-KAAWEFLEENRDSVKFELTAVNPVYVFGPQMFDK- 207 + +E+ + + + G K AE + W+ + K VNP Q+ + Sbjct: 56 DREEFEAAKRGLIAPFSGQIKNAEGQVVWDMGAYQFLNDKDAADTVNPSLWRQAQLNNIA 115 Query: 208 ---DVKKHLNTSCELVNSLMHLSPEDKIPELFGGYIDVRDVAKAHLVAF 253 +V L L + M + D L A+A L + Sbjct: 116 GLFEVMPKLYQVRGLDPANMTIIEGDSGLVLIDTLTTAE-TARAALDLY 163 >2WEK-A nrPDB Length = 341 Score = 29.5 bits (64), Expect = 2.3, Method: Composition-based stats. Identities = 19/66 (28%), Positives = 28/66 (42%), Gaps = 1/66 (1%) Query: 3 VFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNP-KFSMEVVPDISKL 61 V V+ A G Q + L K VIG+ S EK+ L + P + E V + K Sbjct: 146 VLVTAAAGGTGQFAMQLSKKAKCHVIGTCSSDEKSAFLKSLGCDRPINYKTEPVGTVLKQ 205 Query: 62 DAFDHV 67 + + V Sbjct: 206 EYPEGV 211 >2TMD-A nrPDB Length = 729 Score = 29.5 bits (64), Expect = 2.4, Method: Composition-based stats. Identities = 9/42 (21%), Positives = 19/42 (45%), Gaps = 1/42 (2%) Query: 2 SVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEA 43 SV + GA G +L++ Y V + +++ +L + Sbjct: 391 SVLIVGA-GPSGSEAARVLMESGYTVHLTDTAEKIGGHLNQV 431 >5ZG8-A nrPDB Length = 438 Score = 28.7 bits (62), Expect = 3.6, Method: Composition-based stats. Identities = 17/110 (15%), Positives = 31/110 (28%), Gaps = 4/110 (3%) Query: 47 NPKFSMEVVPDISKLDAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVN-GVK 105 + S E+ A + + H + A D E L + G Sbjct: 252 LERRSRELEMLGRDPKALEPAAEGHYPRLTYKEAVALVNRIAQEDPEVPPLPYGEDFGAP 311 Query: 106 GILHSIKKYAAD-SVERVVLTSSYAAVFDMAKENDKSLTFNEESWNPATW 154 +++ VER + A + D L N++ P + Sbjct: 312 HEAALSRRFDRPVFVER--YPARIKAFYMEPDPEDPELVLNDDLLAPEGY 359 >3PVW-A nrPDB Length = 695 Score = 28.3 bits (61), Expect = 4.5, Method: Composition-based stats. Identities = 18/74 (24%), Positives = 28/74 (37%), Gaps = 13/74 (17%) Query: 230 DKIPELFGGYIDVRDVAKAH-------------LVAFQKRETIGQRLIVSEARFTMQDVL 276 +KI GY+ RD H + ++K ET +RL+ S F + Sbjct: 56 EKIFSQKLGYLLFRDFCLKHLEEAKPLVEFYEEIKKYEKLETEEERLVCSREIFDTYIMK 115 Query: 277 DILNEDFPVLKGNI 290 ++L P K I Sbjct: 116 ELLACSHPFSKSAI 129 >4HP8-A nrPDB Length = 247 Score = 27.6 bits (59), Expect = 9.1, Method: Composition-based stats. Identities = 20/99 (20%), Positives = 38/99 (38%), Gaps = 8/99 (8%) Query: 4 FVSGANGFIAQHIVDLLLKEDYKVI-GSARSQEKAENLTEAFGNNPKFSMEVVPDISKLD 62 V+GAN + Q I L +V+ + R+ ++ ++ G N + ++ D + Sbjct: 13 LVTGANTGLGQAIAVGLAAAGAEVVCAARRAPDETLDIIAKDGGN---ASALLIDFADPL 69 Query: 63 AFDHVFQKHGKDI----KIVLHTASPFCFDITDSERDLL 97 A F G DI ++ A F D + + Sbjct: 70 AAKDSFTDAGFDILVNNAGIIRRADSVEFSELDWDEVMD 108 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.308 0.115 0.274 Lambda K H 0.267 0.0357 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 10,545,476 Number of Sequences: 36641 Number of extensions: 372564 Number of successful extensions: 1495 Number of sequences better than 10.0: 138 Number of HSP's better than 10.0 without gapping: 102 Number of HSP's successfully gapped in prelim test: 74 Number of HSP's that attempted gapping in prelim test: 1253 Number of HSP's gapped (non-prelim): 180 length of query: 342 length of database: 10,336,785 effective HSP length: 98 effective length of query: 244 effective length of database: 6,745,967 effective search space: 1646015948 effective search space used: 1646015948 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 59 (27.5 bits)