BLASTP 2.2.23 [Feb-03-2010]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment: Altschul, Stephen F.,
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Reference for composition-based statistics starting in round 2:
Schaffer, Alejandro A., L. Aravind, Thomas L. Madden,
Sergei Shavirin, John L. Spouge, Yuri I. Wolf,
Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005.
Query= Q12068
(342 letters)
Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta
36,641 sequences; 10,336,785 total letters
Searching..................................................done
Results from round 1
Score E
Sequences producing significant alignments: (bits) Value
4PVC-A nrPDB 706 0.0
5B6K-A nrPDB 421 e-118
5YWN-A nrPDB 294 3e-80
4QUK-A nrPDB 117 9e-27
4R1T-A nrPDB 112 3e-25
1ZZE-A nrPDB 108 5e-24
4R1U-A nrPDB 105 4e-23
3HFS-A nrPDB 103 1e-22
2NNL-D nrPDB 88 7e-18
2P4H-X nrPDB 65 6e-11
1GY8-A nrPDB 47 2e-05
4LIS-A nrPDB 41 8e-04
4WKG-A nrPDB 40 0.002
5CDY-A nrPDB 39 0.004
3RSH-A nrPDB 35 0.037
5JRE-A nrPDB 35 0.065
1Q7C-A nrPDB 35 0.067
6BI4-A nrPDB 32 0.32
2J3K-A nrPDB 32 0.33
1UDA-A nrPDB 32 0.33
6BWL-A nrPDB 32 0.43
2C54-A nrPDB 32 0.47
3MYR-B nrPDB 31 0.60
4WOK-A nrPDB 31 0.66
1I3M-A nrPDB 30 1.3
2Q1W-A nrPDB 30 2.0
1E5Q-A nrPDB 29 2.5
5XWI-A nrPDB 29 2.9
6FKI-F nrPDB 28 4.6
4R7O-A nrPDB 28 4.6
3F9I-A nrPDB 28 5.8
2AXQ-A nrPDB 28 6.4
3ENK-A nrPDB 28 8.3
>4PVC-A nrPDB
Length = 342
Score = 706 bits (1821), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 342/342 (100%), Positives = 342/342 (100%)
Query: 1 MSVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISK 60
MSVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISK
Sbjct: 1 MSVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISK 60
Query: 61 LDAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAADSVE 120
LDAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAADSVE
Sbjct: 61 LDAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAADSVE 120
Query: 121 RVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAAWEFL 180
RVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAAWEFL
Sbjct: 121 RVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAAWEFL 180
Query: 181 EENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLSPEDKIPELFGGYI 240
EENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLSPEDKIPELFGGYI
Sbjct: 181 EENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLSPEDKIPELFGGYI 240
Query: 241 DVRDVAKAHLVAFQKRETIGQRLIVSEARFTMQDVLDILNEDFPVLKGNIPVGKPGSGAT 300
DVRDVAKAHLVAFQKRETIGQRLIVSEARFTMQDVLDILNEDFPVLKGNIPVGKPGSGAT
Sbjct: 241 DVRDVAKAHLVAFQKRETIGQRLIVSEARFTMQDVLDILNEDFPVLKGNIPVGKPGSGAT 300
Query: 301 HNTLGATLDNKKSKKLLGFKFRNLKETIDDTASQILKFEGRI 342
HNTLGATLDNKKSKKLLGFKFRNLKETIDDTASQILKFEGRI
Sbjct: 301 HNTLGATLDNKKSKKLLGFKFRNLKETIDDTASQILKFEGRI 342
>5B6K-A nrPDB
Length = 366
Score = 421 bits (1083), Expect = e-118, Method: Compositional matrix adjust.
Identities = 212/341 (62%), Positives = 256/341 (75%), Gaps = 4/341 (1%)
Query: 2 SVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKL 61
+VFVSGA GFIAQH+V LL ++YKVIGS RS EK ++L F+ E+V DIS
Sbjct: 23 TVFVSGATGFIAQHVVRQLLDQNYKVIGSVRSAEKGDHLKNVIFKGGDFNYEIVKDISDP 82
Query: 62 DAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAADSVER 121
AFDHVF+KHGKDIK+VLHTASPF F+ TD E+DLLIPAVNG KGIL SIKKYAA +VER
Sbjct: 83 TAFDHVFEKHGKDIKVVLHTASPFHFNTTDIEKDLLIPAVNGTKGILESIKKYAAQTVER 142
Query: 122 VVLTSSYAA---VFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAAWE 178
VV+TSS+AA DM D S T EESWN TWESCQSDP+ YCGSKKFAEKAAW+
Sbjct: 143 VVVTSSFAANTSTVDMFYAKDSSKTITEESWNQDTWESCQSDPIRGYCGSKKFAEKAAWD 202
Query: 179 FLEENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLSPEDKIPELFGG 238
F N+DSVKF+L+ +NPVYVFGPQ + + KK LNTS E++NSL+HL +D +PE GG
Sbjct: 203 FYNANKDSVKFKLSIINPVYVFGPQNYVEPGKKILNTSSEVINSLVHLKKDDPLPEFAGG 262
Query: 239 YIDVRDVAKAHLVAFQKRETIGQRLIVSEARFTMQDVLDILNEDFPVLKGNIPVGKPGSG 298
+IDVRDVAKAH++AFQK E I QRL++ FT Q +LDI+NE FP LKG IP GKPG+G
Sbjct: 263 HIDVRDVAKAHILAFQKDELIEQRLMLHAGLFTTQTLLDIINEQFPELKGKIPAGKPGTG 322
Query: 299 ATHNTLGATLDNKKSKKLLGFKFRNLKETIDDTASQILKFE 339
+ L +DN K+KKLLGF+F +LK+ + DT SQIL+ E
Sbjct: 323 NPDDAL-TPVDNSKTKKLLGFEFIDLKKDLYDTISQILEAE 362
>5YWN-A nrPDB
Length = 334
Score = 294 bits (753), Expect = 3e-80, Method: Compositional matrix adjust.
Identities = 153/339 (45%), Positives = 228/339 (67%), Gaps = 8/339 (2%)
Query: 2 SVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKL 61
SVFVSGA G++AQ I+ L+L + YKV+GS RS+EK NL + +G++ FS EVV + +
Sbjct: 4 SVFVSGATGYLAQQIIALVLSKGYKVVGSVRSEEKGANLKKLYGDD--FSYEVVKVLEQK 61
Query: 62 DAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAADSVER 121
AFD +KH ++ I LHTASP F++ D+E+++LIPA+NG K +L SIK A + R
Sbjct: 62 GAFDEALKKH-PEVTIFLHTASPVTFEVEDTEKEILIPAINGTKYVLQSIKD-VAPQITR 119
Query: 122 VVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAAWEFLE 181
VV TSS A+ + + +E SW+ ++E ++ V AY GSK+FAE+AAWEF+E
Sbjct: 120 VVYTSSVVAMSVPEELGSPDVVLSEASWSSLSYEQSKTHGVLAYFGSKQFAERAAWEFVE 179
Query: 182 ENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLSPEDKIPELFGGYID 241
+ + + F L+ VNPVY+FGPQ D++VK LN S E+VNS++ L+ +D +P G +ID
Sbjct: 180 QEKPN--FALSTVNPVYIFGPQAKDEEVKGTLNHSAEMVNSVLKLNKDDDVPATTGTFID 237
Query: 242 VRDVAKAHLVAFQKRETIGQRLIVSEARFTMQDVLDILNEDFPVLKGNIPVGKPGSGATH 301
VRDVAKAHL AF+K E G+RL++S RF Q +LD++ ++FP L +PVGKP S
Sbjct: 238 VRDVAKAHLAAFEKDEAKGERLLLSNTRFNGQTLLDVVRKNFPQLADKLPVGKPHSD--D 295
Query: 302 NTLGATLDNKKSKKLLGFKFRNLKETIDDTASQILKFEG 340
+ ++KK+KK+LGF++ + + ++ D+ Q+LK +G
Sbjct: 296 FSAFKEWNDKKTKKILGFEYFDFETSVVDSIKQVLKVQG 334
>4QUK-A nrPDB
Length = 319
Score = 117 bits (292), Expect = 9e-27, Method: Compositional matrix adjust.
Identities = 93/289 (32%), Positives = 150/289 (51%), Gaps = 27/289 (9%)
Query: 3 VFVSGANGFIAQHIVDLLLKEDYKVIGSARSQ---EKAENLTEAFGNNPKFSMEVVPDIS 59
V V+GA+G+IA +V LLL Y V + R +K ++L + G + + ++
Sbjct: 3 VCVTGASGYIASWLVRLLLHRGYTVKATVRDPNDPKKVDHLVKLDGAKERLQL-FKANLL 61
Query: 60 KLDAFDHVFQK-HGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAADS 118
+ AFD V Q HG V HTASPF D+ D + +L+ PA+ G +L+S K + S
Sbjct: 62 EEGAFDSVVQGCHG-----VFHTASPFYHDVKDPQAELIDPALKGTLNVLNSCAK--SPS 114
Query: 119 VERVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAAWE 178
++RVVLTSS AAV K + +E + A + C + Y S AE+AAW+
Sbjct: 115 LKRVVLTSSIAAVAYNGKPRTPDVVVDETWFTDADF--CAKSNL-WYVVSATLAEEAAWK 171
Query: 179 FLEENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLSPEDKIPELFGG 238
F++EN ++ +NP V GP + + LNTS + +L++ + P G
Sbjct: 172 FVKENN----IDMVTINPAMVIGPLL-----QPVLNTSAAAILNLINGA--QTFPNASFG 220
Query: 239 YIDVRDVAKAHLVAFQKRETIGQRLIVSEARFTMQDVLDILNEDFPVLK 287
+++V+DVA AH++A++ G+ +V E +V+ IL E +P L+
Sbjct: 221 WVNVKDVANAHILAYENASASGRHCLV-ERVAHYSEVVRILRELYPSLQ 268
>4R1T-A nrPDB
Length = 337
Score = 112 bits (280), Expect = 3e-25, Method: Compositional matrix adjust.
Identities = 100/337 (29%), Positives = 163/337 (48%), Gaps = 37/337 (10%)
Query: 3 VFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAEN--LTEAFGNNPKFSMEVVPDISK 60
V V+GA GFIA +V +LL++ Y V G+ R+ + +N L E G + ++ K
Sbjct: 13 VCVTGAGGFIASWLVKILLEKGYTVRGTVRNPDDPKNGHLRELEGAKERLTL------CK 66
Query: 61 LDAFDHVFQKHG-KDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAADSV 119
D D+ + V HTASP +TD ++ PAV G K ++++ A +V
Sbjct: 67 ADLLDYQSLREAINGCDGVFHTASP----VTDDPEQMVEPAVIGTKNVINAA---AEANV 119
Query: 120 ERVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAAWEF 179
RVV TSS AV+ M D +E W+ + C++ N YC K AE+AAWE
Sbjct: 120 RRVVFTSSIGAVY-MDPNRDPETVVDETCWSDPDF--CKNTK-NWYCYGKMVAEQAAWEE 175
Query: 180 LEENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLSPEDKI-PELFGG 238
+E +L +NPV V GP + + +N S +++ L +L+ K
Sbjct: 176 AKEK----GVDLVVINPVLVQGPLL-----QTTVNAS--VLHILKYLTGSAKTYANSVQA 224
Query: 239 YIDVRDVAKAHLVAFQKRETIGQRLIVSEARFTMQDVLDILNEDFPVLKGNIPVGKPGSG 298
Y+DV+DVA AH++ ++ E G R + +E+ DV++IL++ FP P+ S
Sbjct: 225 YVDVKDVALAHILLYETPEASG-RYLCAESVLHRGDVVEILSKFFP----EYPIPTKCSD 279
Query: 299 ATHNTLGATLDNKKSKKLLGFKFRNLKETIDDTASQI 335
T + + + K LG +F +K+ + +T +
Sbjct: 280 VTKPRVKPYKFSNQKLKDLGLEFTPVKQCLYETVKSL 316
>1ZZE-A nrPDB
Length = 342
Score = 108 bits (269), Expect = 5e-24, Method: Compositional matrix adjust.
Identities = 101/339 (29%), Positives = 160/339 (47%), Gaps = 28/339 (8%)
Query: 3 VFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAF-GNNP-KFSMEVVPDISK 60
V V+GANGF+A H+V+ LL+ YKV G+ARS K NL + + P +F VV D+ K
Sbjct: 14 VLVTGANGFVASHVVEQLLEHGYKVRGTARSASKLANLQKRWDAKYPGRFETAVVEDMLK 73
Query: 61 LDAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAAD-SV 119
A+D V K V H AS F ++ +++ PA+ G L++++ AA SV
Sbjct: 74 QGAYDEVI----KGAAGVAHIASVVSF--SNKYDEVVTPAIGGT---LNALRAAAATPSV 124
Query: 120 ERVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESC----QSDPVNA---YCGSKKFA 172
+R VLTSS + + K N + + +E+SWN + + +SDP + Y SK A
Sbjct: 125 KRFVLTSSTVSAL-IPKPNVEGIYLDEKSWNLESIDKAKTLPESDPQKSLWVYAASKTEA 183
Query: 173 EKAAWEFLEENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLSPEDKI 232
E AAW+F++EN+ F L AV P Y G +FD + + + + +SP +
Sbjct: 184 ELAAWKFMDENKP--HFTLNAVLPNYTIG-TIFDPETQSGSTSGWMMSLFNGEVSPALAL 240
Query: 233 -PELFGGYIDVRDVAKAHLVAFQKRETIGQRLIVSEARFTMQDVLDILNEDFPVLKGNIP 291
P + Y+ D+ HL + +R+ + F VL + +P P
Sbjct: 241 MPPQY--YVSAVDIGLLHLGCLVLPQIERRRVYGTAGTFDWNTVLATFRKLYP--SKTFP 296
Query: 292 VGKPGSGATHNTLGATLDNKKSKKLLGFKFRNLKETIDD 330
P G + + K L +R+++E+I D
Sbjct: 297 ADFPDQGQDLSKFDTAPSLEILKSLGRPGWRSIEESIKD 335
>4R1U-A nrPDB
Length = 349
Score = 105 bits (261), Expect = 4e-23, Method: Compositional matrix adjust.
Identities = 100/340 (29%), Positives = 156/340 (45%), Gaps = 41/340 (12%)
Query: 2 SVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAEN--LTEAFGNNPKFSMEVVPDIS 59
+V V+GA GFIA +V LLL+ Y V G+ R+ E +N L E G + ++ V D+
Sbjct: 29 TVCVTGAGGFIASWLVKLLLERGYTVRGTVRNPEDPKNGHLKELEGARERLTLHKV-DLL 87
Query: 60 KLDAFDHVFQK-HGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAADS 118
L + V HG V HTASP +TD+ ++L PAVNG K + I A
Sbjct: 88 DLQSIQSVVHGCHG-----VFHTASP----VTDNPDEMLEPAVNGTKNV---IIASAEAK 135
Query: 119 VERVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAAWE 178
V RVV TSS V+ M + + +E W + E C++ N YC K AE++AW+
Sbjct: 136 VRRVVFTSSIGTVY-MDPNTSRDVVVDESYW--SDLEHCKNTK-NWYCYGKTVAEQSAWD 191
Query: 179 FLEENRDSVKFELTAVNPVYVFGPQMFDKDVK--KHLNTSCE-LVNSLMHLSPEDKIPEL 235
+EN+ + V + P + + K+LN + + VN+
Sbjct: 192 IAKENQVDLVVVNPVVVLGPLLQPTINASTIHILKYLNGAAKTYVNATQ----------- 240
Query: 236 FGGYIDVRDVAKAHLVAFQKRETIGQRLIVSEARFTMQDVLDILNEDFPVLKGNIPVGKP 295
Y+ V+DVA AHL+ ++ G R I E +V++IL + FP P+
Sbjct: 241 --SYVHVKDVALAHLLVYETNSASG-RYICCETALHRGEVVEILAKYFP----EYPLPTK 293
Query: 296 GSGATHNTLGATLDNKKSKKLLGFKFRNLKETIDDTASQI 335
S + + + + K LG +F +K+ + DT +
Sbjct: 294 CSDEKNPRVKPYKFSNQKLKDLGLEFTPVKQCLYDTVRSL 333
>3HFS-A nrPDB
Length = 338
Score = 103 bits (256), Expect = 1e-22, Method: Compositional matrix adjust.
Identities = 84/291 (28%), Positives = 136/291 (46%), Gaps = 25/291 (8%)
Query: 5 VSGANGFIAQHIVDLLLKEDYKVIGSAR---SQEKAENLTE--AFGNNPKFSMEVVPDIS 59
V G GF+A +V LLL++ Y V + R +Q+K +L E G+ F ++ ++S
Sbjct: 14 VVGGTGFVASLLVKLLLQKGYAVNTTVRDPDNQKKVSHLLELQELGDLKIFRADLTDELS 73
Query: 60 KLDAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAADSV 119
F+ V H A+P F D E D++ PA+ GV ++ + + A SV
Sbjct: 74 --------FEAPIAGCDFVFHVATPVHFASEDPENDMIKPAIQGVVNVMKACTR--AKSV 123
Query: 120 ERVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAAWEF 179
+RV+LTSS AAV + + + L +E++W + + P Y SK AEKAAW+F
Sbjct: 124 KRVILTSSAAAV-TINQLDGTGLVVDEKNWTDIEFLTSAKPPTWGYPASKTLAEKAAWKF 182
Query: 180 LEENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLSPEDKIPELFGGY 239
EEN +L V P + G + DV + + L+ L K ++ G
Sbjct: 183 AEENN----IDLITVIPTLMAGSSL-TSDVPSSIGLAMSLITGNEFLINGMKGMQMLSGS 237
Query: 240 ID---VRDVAKAHLVAFQKRETIGQRLIVSEARFTMQDVLDILNEDFPVLK 287
+ V DV +AH+ +K G R I A ++ ++ L++ +P K
Sbjct: 238 VSIAHVEDVCRAHIFVAEKESASG-RYICCAANTSVPELAKFLSKRYPQYK 287
>2NNL-D nrPDB
Length = 337
Score = 87.8 bits (216), Expect = 7e-18, Method: Compositional matrix adjust.
Identities = 85/326 (26%), Positives = 142/326 (43%), Gaps = 32/326 (9%)
Query: 2 SVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVV---PDI 58
+V V+GA+GFI +V LL+ Y V + R + + + PK + D+
Sbjct: 7 TVCVTGASGFIGSWLVMRLLERGYTVRATVRDPTNVKKVKHLL-DLPKAETHLTLWKADL 65
Query: 59 SKLDAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAADS 118
+ +FD K V H A+P F+ D E +++ P + G+ GI+ S AA +
Sbjct: 66 ADEGSFDEAI----KGCTGVFHVATPMDFESKDPENEVIKPTIEGMLGIMKSCA--AAKT 119
Query: 119 VERVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNA--YCGSKKFAEKAA 176
V R+V TSS V + + ++E W+ E C++ + A Y SK AE+AA
Sbjct: 120 VRRLVFTSSAGTV---NIQEHQLPVYDESCWSDM--EFCRAKKMTAWMYFVSKTLAEQAA 174
Query: 177 WEFLEENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLSPEDKIPELF 236
W++ +EN + + P V GP + + + + H S +
Sbjct: 175 WKYAKENN----IDFITIIPTLVVGPFIMSSMPPSLITALSPITGNEAHYSIIRQ----- 225
Query: 237 GGYIDVRDVAKAHLVAFQKRETIGQRLIVSEARFTMQDVLDILNEDFPVLKGNIPVGKPG 296
G ++ + D+ AH+ F+ + G R I S + D+ +L E +P + NIP
Sbjct: 226 GQFVHLDDLCNAHIYLFENPKAEG-RYICSSHDCIILDLAKMLREKYP--EYNIPT--EF 280
Query: 297 SGATHNTLGATLDNKKSKKLLGFKFR 322
G N +KK LGF+F+
Sbjct: 281 KGVDENLKSVCFSSKKLTD-LGFEFK 305
>2P4H-X nrPDB
Length = 322
Score = 64.7 bits (156), Expect = 6e-11, Method: Compositional matrix adjust.
Identities = 90/354 (25%), Positives = 149/354 (42%), Gaps = 49/354 (13%)
Query: 3 VFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEV---VPDIS 59
V V+G GF+ I+ LL+ Y V + R+ + + N P S ++ D+S
Sbjct: 4 VCVTGGTGFLGSWIIKSLLENGYSVNTTIRADPERKRDVSFLTNLPGASEKLHFFNADLS 63
Query: 60 KLDAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAADSV 119
D+F + + HTASP F +++ E + V+G GIL + + +V
Sbjct: 64 NPDSFAAAIEGCVG----IFHTASPIDFAVSEPEEIVTKRTVDGALGILKACVN--SKTV 117
Query: 120 ERVVLTSSYAAVFDMAKENDKSLTFNEESWN---------PATWESCQSDPVNAYCGSKK 170
+R + TSS +AV K+ D +E W+ P W Y SK
Sbjct: 118 KRFIYTSSGSAVSFNGKDKD---VLDESDWSDVDLLRSVKPFGWN---------YAVSKT 165
Query: 171 FAEKAAWEFLEENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLSPED 230
AEKA EF E+N ++ V + P + + V L S E L+ L ++
Sbjct: 166 LAEKAVLEFGEQN---------GIDVVTLILPFIVGRFVCPKLPDSIEKALVLV-LGKKE 215
Query: 231 KIPELFGGYIDVRDVAKAHLVAFQKRETIGQRLIVSEARFTMQDVLDILNEDFPVLKGNI 290
+I + V DVA+AH+ + G R S ++++ +L+ +P + +
Sbjct: 216 QIGVTRFHMVHVDDVARAHIYLLE-NSVPGGRYNCSPFIVPIEEMSQLLSAKYPEYQ-IL 273
Query: 291 PVGKPGSGATHNTLGATLDNKKSKKLL--GFKFRNLKETIDDTASQILKFEGRI 342
V + GA L + +KKL+ GF F+ E + D A Q K +G +
Sbjct: 274 TVDE-----LKEIKGARLPDLNTKKLVDAGFDFKYTIEDMFDDAIQCCKEKGYL 322
>1GY8-A nrPDB
Length = 397
Score = 46.6 bits (109), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 71/306 (23%), Positives = 125/306 (40%), Gaps = 61/306 (19%)
Query: 1 MSVFVSGANGFIAQHIVDLLLKE-DYKVI---------GSARSQEKAEN----LTEAFGN 46
M V V G G+I H V LL++ ++ V+ G + E EN L ++ G
Sbjct: 3 MRVLVCGGAGYIGSHFVRALLRDTNHSVVIVDSLVGTHGKSDHVETRENVARKLQQSDGP 62
Query: 47 NP----KFSMEVVPDISKLDAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVN 102
P +++ V D+ D + VF +HG I V+H + + +S RD L N
Sbjct: 63 KPPWADRYAALEVGDVRNEDFLNGVFTRHGP-IDAVVHMCA--FLAVGESVRDPLKYYDN 119
Query: 103 GVKGILHSIKKYAADSVERVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPV 162
V GIL ++ ++++ +SS AA+F S++ N E + + + P
Sbjct: 120 NVVGILRLLQAMLLHKCDKIIFSSS-AAIF--GNPTMGSVSTNAEPID----INAKKSPE 172
Query: 163 NAYCGSKKFAEKAAWEFLEENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNS 222
+ Y SK AE+ + + ++ + + G D D+ +H S L+
Sbjct: 173 SPYGESKLIAER----MIRDCAEAYGIKGICLRYFNACGAHE-DGDIGEHYQGSTHLIPI 227
Query: 223 LM-----HLSPE-----------DKIPELFGG------------YIDVRDVAKAHLVAFQ 254
++ ++P+ DK +FG Y+ V D+A AH++A
Sbjct: 228 ILGRVMSDIAPDQRLTIHEDASTDKRMPIFGTDYPTPDGTCVRDYVHVCDLASAHILALD 287
Query: 255 KRETIG 260
E +G
Sbjct: 288 YVEKLG 293
>4LIS-A nrPDB
Length = 371
Score = 40.8 bits (94), Expect = 8e-04, Method: Compositional matrix adjust.
Identities = 55/192 (28%), Positives = 82/192 (42%), Gaps = 22/192 (11%)
Query: 2 SVFVSGANGFIAQHIVDLLLKEDYKVIGS---ARSQEKAENLTEAF-GNNPKFSMEVVPD 57
SV V+G G+I LL+ YKV+ + S +A N E G +F+ D
Sbjct: 5 SVLVTGGTGYIGSFTTLALLEAGYKVVVADNLYNSSAEALNRIELISGKKAEFAQL---D 61
Query: 58 ISKLDAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAAD 117
++ AFD VF+ H DI V+H A+ E+ L VN V G + ++
Sbjct: 62 VTDEAAFDKVFEAH-PDIDSVIHFAALKAVG-ESGEKPLDYYHVN-VYGTICLLRSMVRH 118
Query: 118 SVERVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFA-EKAA 176
+V +V +SS A V+ A + E C P N Y G+ KFA E A
Sbjct: 119 NVTNIVFSSS-ATVYGDATRFPDMIPIPEH---------CPLGPTNPY-GNTKFAIELAI 167
Query: 177 WEFLEENRDSVK 188
+ + R++ K
Sbjct: 168 TDVINAQRNNAK 179
>4WKG-A nrPDB
Length = 660
Score = 40.0 bits (92), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 61/266 (22%), Positives = 106/266 (39%), Gaps = 57/266 (21%)
Query: 3 VFVSGANGFIAQHIVDLLLKED-YKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKL 61
V + G NGFI H+ + LL+ED Y+V G + + F N+P F V DIS
Sbjct: 318 VLILGVNGFIGNHLTERLLREDHYEVYG----LDIGSDAISRFLNHPHFHF-VEGDISIH 372
Query: 62 DAFDHVFQKHGKDIKIVL----------HTASPFCFDITDSERDLLIPAVNGVKGILHSI 111
+ + H K +VL +T +P D E +L I
Sbjct: 373 SEW---IEYHVKKCDVVLPLVAIATPIEYTRNPLRVFELDFEENL-------------RI 416
Query: 112 KKYAADSVERVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNA----YCG 167
+Y +R++ S+ + V+ M + F+E+ N PVN Y
Sbjct: 417 IRYCVKYRKRIIFPST-SEVYGMCSDK----YFDEDHSNLIV------GPVNKPRWIYSV 465
Query: 168 SKKFAEKAAWEFLEENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLS 227
SK+ ++ W + E+ + T P GP++ + + + + +S + +++L
Sbjct: 466 SKQLLDRVIWAYGEKE----GLQFTLFRPFNWMGPRLDNLNAAR-IGSSRAITQLILNLV 520
Query: 228 PEDKIPELFGG-----YIDVRDVAKA 248
I + GG + D+RD +A
Sbjct: 521 EGSPIKLIDGGKQKRCFTDIRDGIEA 546
>5CDY-A nrPDB
Length = 244
Score = 38.5 bits (88), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 23/80 (28%), Positives = 42/80 (52%)
Query: 4 FVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKLDA 63
V+GA+ I + I +LL++ VIG+A S++ AE ++ G N K M V D + +D
Sbjct: 9 LVTGASRGIGRAIAELLVERGACVIGTATSEKGAEAISAYLGENGKGLMLNVVDPTSIDT 68
Query: 64 FDHVFQKHGKDIKIVLHTAS 83
+ ++ I+++ A
Sbjct: 69 VLATIRAEFGEVDILVNNAG 88
>3RSH-A nrPDB
Length = 251
Score = 35.4 bits (80), Expect = 0.037, Method: Compositional matrix adjust.
Identities = 17/46 (36%), Positives = 29/46 (63%)
Query: 4 FVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPK 49
V+GA+ I + I +LL + KVIG+A S+ A+ +++ G+N K
Sbjct: 16 LVTGASRGIGKAIAELLAERGAKVIGTATSESGAQAISDYLGDNGK 61
>5JRE-A nrPDB
Length = 219
Score = 34.7 bits (78), Expect = 0.065, Method: Compositional matrix adjust.
Identities = 31/117 (26%), Positives = 59/117 (50%), Gaps = 9/117 (7%)
Query: 94 RDLLIPAVNGVKGILHSIKKYAADSVERVVLTS--SYAAVFDMAKENDKSL-TFNEESWN 150
R ++P ++ +K +++ + V+R + S S + ++ M +E+ KS + EE N
Sbjct: 32 RGSMLPNLDNLKEEYQKLEEKKQEIVDRSIRMSKLSKSLIYSMIREDYKSADKYKEELTN 91
Query: 151 PA--TWESCQSDPV---NAYCGSKKFAEKAA-WEFLEENRDSVKFELTAVNPVYVFG 201
A E + P+ N + G +++ E A + +++ENR K EL VY+FG
Sbjct: 92 LAKTQIEELKKYPMFYSNGFIGLQEYVEALALYYYIKENRIPSKEELGVDTWVYLFG 148
>1Q7C-A nrPDB
Length = 244
Score = 34.7 bits (78), Expect = 0.067, Method: Compositional matrix adjust.
Identities = 21/80 (26%), Positives = 41/80 (51%)
Query: 4 FVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKLDA 63
V+GA+ I + I + L KVIG+A S+ A+ +++ G N K M V D + +++
Sbjct: 9 LVTGASRGIGRAIAETLAARGAKVIGTATSENGAQAISDYLGANGKGLMLNVTDPASIES 68
Query: 64 FDHVFQKHGKDIKIVLHTAS 83
+ ++ I+++ A
Sbjct: 69 VLEKIRAEFGEVDILVNNAG 88
>6BI4-A nrPDB
Length = 346
Score = 32.3 bits (72), Expect = 0.32, Method: Compositional matrix adjust.
Identities = 53/248 (21%), Positives = 107/248 (43%), Gaps = 37/248 (14%)
Query: 1 MSVFVSGANGFIAQHIVDLLLK--EDYKVIG-SARSQEKAENLTEAFGNNPKFSMEVVPD 57
M++ V+G GFI + V +L+ E YK+I A + N ++ ++P + V +
Sbjct: 25 MNILVTGGAGFIGSNFVHYMLQSYETYKIINFDALTYSGNLNNVKSIQDHPNYYF-VKGE 83
Query: 58 ISKLDAFDHVFQKHGKDIKIVLHTASPFCFDIT-DSERDLLIPAVNGVKGILHSIKKYAA 116
I + +HV ++ +D++++++ A+ D + ++ V G +L +KKY
Sbjct: 84 IQNGELLEHVIKE--RDVQVIVNFAAESHVDRSIENPIPFYDTNVIGTVTLLELVKKYPH 141
Query: 117 DSVERVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAA 176
+ +V Y ++ K+ F EE+ P P + Y SK A+ A
Sbjct: 142 IKLVQVSTDEVYGSL-------GKTGRFTEET--PLA-------PNSPYSSSKASADMIA 185
Query: 177 WEFLEENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLSPEDKIPELF 236
+ + + V + N +GP + + +L+ ++ + E K L+
Sbjct: 186 LAYYKTYQLPVIVTRCSNN----YGPYQYPE----------KLIPLMVTNALEGKKLPLY 231
Query: 237 GGYIDVRD 244
G ++VRD
Sbjct: 232 GDGLNVRD 239
>2J3K-A nrPDB
Length = 345
Score = 32.3 bits (72), Expect = 0.33, Method: Compositional matrix adjust.
Identities = 19/58 (32%), Positives = 32/58 (55%)
Query: 2 SVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDIS 59
+V+VS A+G + Q + L V+GSA S+EK + L FG + F+ + D++
Sbjct: 158 TVYVSAASGAVGQLVGQLAKMMGCYVVGSAGSKEKVDLLKTKFGFDDAFNYKEESDLT 215
>1UDA-A nrPDB
Length = 338
Score = 32.3 bits (72), Expect = 0.33, Method: Compositional matrix adjust.
Identities = 70/296 (23%), Positives = 106/296 (35%), Gaps = 38/296 (12%)
Query: 1 MSVFVSGANGFIAQHIVDLLLKEDYKVI---GSARSQEKAENLTEAFGN-NPKFSMEVVP 56
M V V+G +G+I H LL+ + VI S+ + E G +P F V
Sbjct: 1 MRVLVTGGSGYIGSHTCVQLLQNGHDVIILDNLCNSKRSVLPVIERLGGKHPTF---VEG 57
Query: 57 DISKLDAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAA 116
DI + H I V+H A + +S + L N V G L I A
Sbjct: 58 DIRNEALMTEILHDHA--IDTVIHFAG--LKAVGESVQKPLEYYDNNVNGTLRLISAMRA 113
Query: 117 DSVERVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAA 176
+V+ + +SS A V+ D ES+ T P + Y SK E+
Sbjct: 114 ANVKNFIFSSS-ATVY-----GDNPKIPYVESFPTGT-------PQSPYGKSKLMVEQIL 160
Query: 177 WEFLEENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLSPEDKIPELF 236
+ + D L NPV +D + N + + + D + +F
Sbjct: 161 TDLQKAQPDWSIALLRYFNPVGAHPSGDMGEDPQGIPNNLMPYIAQVA-VGRRDSL-AIF 218
Query: 237 GG------------YIDVRDVAKAHLVAFQKRETIGQRLIVSEARFTMQDVLDILN 280
G YI V D+A H+VA +K I + VLD++N
Sbjct: 219 GNDYPTEDGTGVRDYIHVMDLADGHVVAMEKLANKPGVHIYNLGAGVGNSVLDVVN 274
>6BWL-A nrPDB
Length = 328
Score = 32.0 bits (71), Expect = 0.43, Method: Compositional matrix adjust.
Identities = 44/203 (21%), Positives = 82/203 (40%), Gaps = 24/203 (11%)
Query: 1 MSVFVSGANGFIAQHIVDLLLKEDYKV-IGSARSQEKAENLTEAFGNNPKFSMEVVPDIS 59
M + V+G GFI + +V LL++ ++V I + N+TE F ++ + DI
Sbjct: 1 MKILVTGGAGFIGRWVVKRLLQDKHEVWILDNLANSTTANITE-FAHDLNLKQCIQGDIK 59
Query: 60 KLDAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAADSV 119
+F+ + D + H A+ ++ DS D N G + +++ V
Sbjct: 60 DKKLVAQLFENNSFD--LCYHLAAS--INVQDSIDDARATFENDTIGTFNLLEQCLNYDV 115
Query: 120 ERVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAAWEF 179
+ V +++ V+D A N + ++ E P + Y GSK AE +
Sbjct: 116 KMVFMST--CMVYDKAT-NIQGIS-----------ELDPIKPASPYAGSKIAAENMVLSY 161
Query: 180 LEENRDSVKFELTAVNPVYVFGP 202
+ K + + P +GP
Sbjct: 162 YY----AYKLPVVVIRPFNTYGP 180
>2C54-A nrPDB
Length = 379
Score = 31.6 bits (70), Expect = 0.47, Method: Compositional matrix adjust.
Identities = 17/42 (40%), Positives = 25/42 (59%), Gaps = 2/42 (4%)
Query: 1 MSVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTE 42
+ + ++GA GFIA HI L E + VI S +K E++TE
Sbjct: 30 LKISITGAGGFIASHIARRLKHEGHYVIAS--DWKKNEHMTE 69
>3MYR-B nrPDB
Length = 561
Score = 31.2 bits (69), Expect = 0.60, Method: Compositional matrix adjust.
Identities = 17/56 (30%), Positives = 28/56 (50%), Gaps = 3/56 (5%)
Query: 104 VKGILHSIKKYAADSVERVVLTSSYAAVFDMAKENDKS---LTFNEESWNPATWES 156
V + ++ + AA ++E +L + +D N KS TFNE W P++W S
Sbjct: 420 VDALYSTLGRTAARALESKILVDAMQGWYDGLIANVKSGDTKTFNETLWEPSSWPS 475
>4WOK-A nrPDB
Length = 336
Score = 31.2 bits (69), Expect = 0.66, Method: Compositional matrix adjust.
Identities = 61/306 (19%), Positives = 114/306 (37%), Gaps = 47/306 (15%)
Query: 2 SVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKL 61
+V V G GFI H LL + Y + +NL+ + ++ V DI
Sbjct: 13 NVLVVGGAGFIGSHTAKLLAGQGYAPV-------VYDNLSTGHQSAVRWGDFVEGDILDQ 65
Query: 62 DAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAADSVER 121
+K+ + ++ AS + + + V G + +L + + +
Sbjct: 66 ARLVETMEKYAP-VAVIHFAASAYVGESVEDPAKYYRNNVGGTQSLLDACR---LTRTQN 121
Query: 122 VVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAAWEFLE 181
V+ +SS A T+ S P E +P+N Y +K AE ++
Sbjct: 122 VIFSSSCA-------------TYGVPSRLP-IGEGEAQNPINPYGRTKLIAEHMLADY-- 165
Query: 182 ENRDSVKFELTAVNPVYVFGPQMFDKDVK---KHLNTSCELVNSLMHLSPEDKIPELFGG 238
+V + L V Y F D D + KH + + ++M + + E++G
Sbjct: 166 ----AVAYGLRYVALRY-FNASGADIDGELGEKHDPETHLIPRAMMAAAGRLDVLEVYGD 220
Query: 239 ------------YIDVRDVAKAHLVAFQKRETIGQRLIVSEARFTMQDVLDILNEDFPVL 286
YI V D+A+AH++A + + G L V+ + +I+ +
Sbjct: 221 DYETPDGTCIRDYIHVTDLARAHVLAVEHLKEAGGNLAVNLGTGRGTSIREIVQSIGRLT 280
Query: 287 KGNIPV 292
++PV
Sbjct: 281 GRSVPV 286
>1I3M-A nrPDB
Length = 348
Score = 30.4 bits (67), Expect = 1.3, Method: Compositional matrix adjust.
Identities = 65/289 (22%), Positives = 104/289 (35%), Gaps = 55/289 (19%)
Query: 3 VFVSGANGFIAQHIVDLLLKEDYKVI----------GSARSQEKAENLTEAFGNNPKFSM 52
V V+G G+I H V LL+ Y + G E + E G + +F
Sbjct: 5 VLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRSVEFEE 64
Query: 53 EVVPDISKLDAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIK 112
DI A +F+K+ V+H A G+K + S++
Sbjct: 65 M---DILDQGALQRLFKKY--SFMAVIHFA--------------------GLKAMGESVQ 99
Query: 113 KYAADSVERVVLTSSYAAVFDMAKENDKSLTFNEES---WNPATWESCQSDPV----NAY 165
K RV LT + + M K+L F+ + NP ++ P N Y
Sbjct: 100 K--PLDYYRVNLTGTIQLLEIMKAHGVKNLVFSSSATVYGNPQYLPLDEAHPTGGCTNPY 157
Query: 166 CGSKKFAEKAAWEFLEENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSL-- 223
SK F E+ + + ++ L NP +D + N V+ +
Sbjct: 158 GKSKFFIEEMIRDLCQADKTWNVVLLRYFNPTGAHASGCIGEDPQGIPNNLMPYVSQVAI 217
Query: 224 -----MHLSPEDKIPELFGG---YIDVRDVAKAHLVAFQK-RETIGQRL 263
+++ D E G YI V D+AK H+ A +K +E G R+
Sbjct: 218 GRREALNVFGNDYDTEDGTGVRDYIHVVDLAKGHIAALRKLKEQCGCRI 266
>2Q1W-A nrPDB
Length = 333
Score = 29.6 bits (65), Expect = 2.0, Method: Compositional matrix adjust.
Identities = 13/27 (48%), Positives = 18/27 (66%)
Query: 3 VFVSGANGFIAQHIVDLLLKEDYKVIG 29
VF++G G I HI +LLL+ KV+G
Sbjct: 24 VFITGICGQIGSHIAELLLERGDKVVG 50
>1E5Q-A nrPDB
Length = 450
Score = 29.3 bits (64), Expect = 2.5, Method: Compositional matrix adjust.
Identities = 22/80 (27%), Positives = 39/80 (48%), Gaps = 5/80 (6%)
Query: 2 SVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKL 61
SV + G +GF+ + +D+L KV + R+ E A+ L+ ++ S++V D
Sbjct: 5 SVLMLG-SGFVTRPTLDVLTDSGIKVTVACRTLESAKKLSAGVQHSTPISLDVNDDA--- 60
Query: 62 DAFDHVFQKHGKDIKIVLHT 81
A D KH I ++ +T
Sbjct: 61 -ALDAEVAKHDLVISLIPYT 79
>5XWI-A nrPDB
Length = 567
Score = 28.9 bits (63), Expect = 2.9, Method: Compositional matrix adjust.
Identities = 23/73 (31%), Positives = 34/73 (46%), Gaps = 5/73 (6%)
Query: 223 LMHLSPEDKIPELFG--GYIDVRDVAKAHLVAFQKRETIGQRLIVSEARFTMQDVLDILN 280
+M + D++ L G GY+ + VA LV Q + QRL F + ++
Sbjct: 177 MMGGATADQVWWLGGPQGYVSYKGVAPTPLVT-QVNQAFAQRLAQPNPGFELP--AQCVS 233
Query: 281 EDFPVLKGNIPVG 293
+DFPV GN VG
Sbjct: 234 KDFPVQAGNRTVG 246
>6FKI-F nrPDB
Length = 498
Score = 28.5 bits (62), Expect = 4.6, Method: Compositional matrix adjust.
Identities = 24/107 (22%), Positives = 51/107 (47%), Gaps = 9/107 (8%)
Query: 210 KKHLNTSCELVNSLMHLS-PEDKIPELFGGYI-DVRDVAKAHL-VAFQKRETIGQ---RL 263
KK+L +++ ++ ++ P K+P ++ I RD A + V + ++ +G R
Sbjct: 17 KKNLGRIAQIIGPVLDVAFPPGKMPNIYNALIVKGRDTAGQPMNVTCEVQQLLGNNRVRA 76
Query: 264 IVSEARFTMQDVLDILNEDFPVLKGNIPVGKPGSGATHNTLGATLDN 310
+ A + +++++ P+ ++PVG G N LG +DN
Sbjct: 77 VAMSATDGLTRGMEVIDTGAPL---SVPVGGATLGRIFNVLGEPVDN 120
>4R7O-A nrPDB
Length = 292
Score = 28.5 bits (62), Expect = 4.6, Method: Compositional matrix adjust.
Identities = 15/67 (22%), Positives = 35/67 (52%), Gaps = 4/67 (5%)
Query: 60 KLDAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHS----IKKYA 115
K+ + +FQK+G+ +K + T SP + + + L+ N + + S I+ ++
Sbjct: 110 KVPTLEEIFQKYGRSMKYYIETKSPDVYPGMEEKLLALLEKYNLIGQNMSSSRVMIQSFS 169
Query: 116 ADSVERV 122
DS++++
Sbjct: 170 KDSLKKI 176
>3F9I-A nrPDB
Length = 249
Score = 28.1 bits (61), Expect = 5.8, Method: Compositional matrix adjust.
Identities = 18/51 (35%), Positives = 29/51 (56%), Gaps = 2/51 (3%)
Query: 4 FVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEV 54
++GA+ I I LL K KVI S ++EK ++L A +N +++EV
Sbjct: 18 LITGASSGIGSAIARLLHKLGSKVIISGSNEEKLKSLGNALKDN--YTIEV 66
>2AXQ-A nrPDB
Length = 467
Score = 28.1 bits (61), Expect = 6.4, Method: Compositional matrix adjust.
Identities = 20/78 (25%), Positives = 36/78 (46%), Gaps = 6/78 (7%)
Query: 8 ANGFIAQHIVDLL-LKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKLDAFDH 66
+GF+AQ ++D L +D V + R+ A+ L + P S + D++ A D
Sbjct: 30 GSGFVAQPVIDTLAANDDINVTVACRTLANAQALAK-----PSGSKAISLDVTDDSALDK 84
Query: 67 VFQKHGKDIKIVLHTASP 84
V + I ++ +T P
Sbjct: 85 VLADNDVVISLIPYTFHP 102
>3ENK-A nrPDB
Length = 341
Score = 27.7 bits (60), Expect = 8.3, Method: Compositional matrix adjust.
Identities = 21/86 (24%), Positives = 34/86 (39%), Gaps = 9/86 (10%)
Query: 2 SVFVSGANGFIAQHIVDLLLKEDYKVIGS----ARSQEKAENLTEAFGNNPKFSMEVVPD 57
++ V+G G+I H LL Y V+ + +E + + G P F D
Sbjct: 7 TILVTGGAGYIGSHTAVELLAHGYDVVIADNLVNSKREAIARIEKITGKTPAFHET---D 63
Query: 58 ISKLDAFDHVFQKHGKDIKIVLHTAS 83
+S A +F H I +H A+
Sbjct: 64 VSDERALARIFDAH--PITAAIHFAA 87
Searching..................................................done
Results from round 2
Score E
Sequences producing significant alignments: (bits) Value
Sequences used in model and found again:
4PVC-A nrPDB 448 e-126
5B6K-A nrPDB 403 e-113
5YWN-A nrPDB 357 3e-99
4R1T-A nrPDB 317 3e-87
2NNL-D nrPDB 314 3e-86
4R1U-A nrPDB 312 1e-85
2P4H-X nrPDB 296 1e-80
4QUK-A nrPDB 294 5e-80
3HFS-A nrPDB 287 6e-78
1ZZE-A nrPDB 274 4e-74
1GY8-A nrPDB 202 2e-52
4WKG-A nrPDB 169 2e-42
4LIS-A nrPDB 156 1e-38
Sequences not found previously or not previously below threshold:
1UDA-A nrPDB 121 4e-28
1Z45-A nrPDB 116 1e-26
2C20-A nrPDB 105 2e-23
3ENK-A nrPDB 105 2e-23
1I3M-A nrPDB 104 4e-23
4WOK-A nrPDB 103 1e-22
1BXK-A nrPDB 84 7e-17
4EJ0-A nrPDB 81 7e-16
2Q1W-A nrPDB 80 2e-15
6BWL-A nrPDB 77 1e-14
2PK3-A nrPDB 73 2e-13
1R66-A nrPDB 73 3e-13
2Q1T-A nrPDB 71 6e-13
1EQ2-A nrPDB 66 2e-11
1KEU-A nrPDB 66 2e-11
1WVG-A nrPDB 65 5e-11
2X86-A nrPDB 64 9e-11
1OC2-A nrPDB 63 2e-10
2HUN-A nrPDB 62 3e-10
3SXP-A nrPDB 59 4e-09
2C54-A nrPDB 58 5e-09
3M2P-A nrPDB 58 6e-09
6BI4-A nrPDB 58 7e-09
1RKX-A nrPDB 57 1e-08
1DB3-A nrPDB 55 4e-08
1ORR-A nrPDB 54 8e-08
2PZM-A nrPDB 53 2e-07
4G5H-A nrPDB 53 2e-07
2GN9-A nrPDB 53 2e-07
4BKP-A nrPDB 53 3e-07
3RUE-A nrPDB 52 3e-07
5UZH-A nrPDB 51 8e-07
6AQY-A nrPDB 50 2e-06
5U9C-A nrPDB 50 2e-06
4J2O-A nrPDB 49 4e-06
3WMX-A nrPDB 48 4e-06
1RPN-A nrPDB 48 8e-06
2Z95-A nrPDB 47 1e-05
1N7G-A nrPDB 47 1e-05
6GCS-E nrPDB 47 1e-05
6GPK-A nrPDB 46 3e-05
5OVL-A nrPDB 45 6e-05
5OVJ-A nrPDB 45 6e-05
3SLK-A nrPDB 44 1e-04
1UZM-A nrPDB 43 2e-04
3RFT-A nrPDB 42 4e-04
4WPG-A nrPDB 42 4e-04
1BDB-A nrPDB 42 4e-04
4B4O-A nrPDB 41 8e-04
3PPI-A nrPDB 41 8e-04
6CI9-A nrPDB 40 0.001
5CDY-A nrPDB 39 0.002
2NM0-A nrPDB 39 0.002
1Q7C-A nrPDB 39 0.002
3RSH-A nrPDB 39 0.003
3OSU-A nrPDB 38 0.004
2DKN-A nrPDB 37 0.011
5F5N-A nrPDB 37 0.012
5ILO-A nrPDB 37 0.013
1HE4-A nrPDB 36 0.018
5ITV-A nrPDB 36 0.024
3LYL-A nrPDB 36 0.025
1QYC-A nrPDB 36 0.025
2GGS-A nrPDB 36 0.031
3UN1-A nrPDB 35 0.041
5LCX-A nrPDB 35 0.042
5GXF-A nrPDB 35 0.048
4IIV-A nrPDB 35 0.049
1CYD-A nrPDB 35 0.054
1GFS-A nrPDB 35 0.055
2J3K-A nrPDB 35 0.057
4IIN-A nrPDB 34 0.062
3F9I-A nrPDB 34 0.072
1AE1-A nrPDB 34 0.11
4CQM-B nrPDB 34 0.11
2Q4B-A nrPDB 34 0.13
4KTT-E nrPDB 33 0.16
2QYS-A nrPDB 33 0.16
3SC6-A nrPDB 33 0.18
1DXY-A nrPDB 33 0.20
2AE2-A nrPDB 33 0.20
1V3V-A nrPDB 33 0.23
3DWF-A nrPDB 33 0.24
1HXH-A nrPDB 33 0.24
1VL0-A nrPDB 33 0.28
1O89-A nrPDB 33 0.28
6G2J-P nrPDB 33 0.29
3D3W-A nrPDB 32 0.32
2B4Q-A nrPDB 32 0.37
5TQV-A nrPDB 32 0.37
2YV2-A nrPDB 32 0.45
2Y05-A nrPDB 32 0.47
2X9N-A nrPDB 31 0.57
3GRP-A nrPDB 31 0.59
4BO1-A nrPDB 31 0.69
1QYD-A nrPDB 31 0.84
5TZ8-A nrPDB 31 0.87
5WQO-A nrPDB 31 0.92
2VCE-A nrPDB 31 0.92
4Q2R-A nrPDB 31 0.94
1P33-A nrPDB 31 0.96
2EXX-A nrPDB 31 1.1
2BKA-A nrPDB 30 1.3
5PGZ-A nrPDB 30 1.4
6DKT-A nrPDB 30 1.4
4IQF-A nrPDB 30 1.4
1H5Q-A nrPDB 30 1.4
5B1Y-A nrPDB 30 1.6
1VIM-A nrPDB 30 1.6
3PVZ-A nrPDB 29 1.9
1YXM-A nrPDB 29 2.0
3V2G-A nrPDB 29 2.2
4AXH-A nrPDB 29 2.3
2WEK-A nrPDB 29 2.3
2TMD-A nrPDB 29 2.4
5ZG8-A nrPDB 29 3.6
3PVW-A nrPDB 28 4.5
4HP8-A nrPDB 28 9.1
>4PVC-A nrPDB
Length = 342
Score = 448 bits (1151), Expect = e-126, Method: Composition-based stats.
Identities = 342/342 (100%), Positives = 342/342 (100%)
Query: 1 MSVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISK 60
MSVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISK
Sbjct: 1 MSVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISK 60
Query: 61 LDAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAADSVE 120
LDAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAADSVE
Sbjct: 61 LDAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAADSVE 120
Query: 121 RVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAAWEFL 180
RVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAAWEFL
Sbjct: 121 RVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAAWEFL 180
Query: 181 EENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLSPEDKIPELFGGYI 240
EENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLSPEDKIPELFGGYI
Sbjct: 181 EENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLSPEDKIPELFGGYI 240
Query: 241 DVRDVAKAHLVAFQKRETIGQRLIVSEARFTMQDVLDILNEDFPVLKGNIPVGKPGSGAT 300
DVRDVAKAHLVAFQKRETIGQRLIVSEARFTMQDVLDILNEDFPVLKGNIPVGKPGSGAT
Sbjct: 241 DVRDVAKAHLVAFQKRETIGQRLIVSEARFTMQDVLDILNEDFPVLKGNIPVGKPGSGAT 300
Query: 301 HNTLGATLDNKKSKKLLGFKFRNLKETIDDTASQILKFEGRI 342
HNTLGATLDNKKSKKLLGFKFRNLKETIDDTASQILKFEGRI
Sbjct: 301 HNTLGATLDNKKSKKLLGFKFRNLKETIDDTASQILKFEGRI 342
>5B6K-A nrPDB
Length = 366
Score = 403 bits (1034), Expect = e-113, Method: Composition-based stats.
Identities = 212/341 (62%), Positives = 256/341 (75%), Gaps = 4/341 (1%)
Query: 2 SVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKL 61
+VFVSGA GFIAQH+V LL ++YKVIGS RS EK ++L F+ E+V DIS
Sbjct: 23 TVFVSGATGFIAQHVVRQLLDQNYKVIGSVRSAEKGDHLKNVIFKGGDFNYEIVKDISDP 82
Query: 62 DAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAADSVER 121
AFDHVF+KHGKDIK+VLHTASPF F+ TD E+DLLIPAVNG KGIL SIKKYAA +VER
Sbjct: 83 TAFDHVFEKHGKDIKVVLHTASPFHFNTTDIEKDLLIPAVNGTKGILESIKKYAAQTVER 142
Query: 122 VVLTSSYAA---VFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAAWE 178
VV+TSS+AA DM D S T EESWN TWESCQSDP+ YCGSKKFAEKAAW+
Sbjct: 143 VVVTSSFAANTSTVDMFYAKDSSKTITEESWNQDTWESCQSDPIRGYCGSKKFAEKAAWD 202
Query: 179 FLEENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLSPEDKIPELFGG 238
F N+DSVKF+L+ +NPVYVFGPQ + + KK LNTS E++NSL+HL +D +PE GG
Sbjct: 203 FYNANKDSVKFKLSIINPVYVFGPQNYVEPGKKILNTSSEVINSLVHLKKDDPLPEFAGG 262
Query: 239 YIDVRDVAKAHLVAFQKRETIGQRLIVSEARFTMQDVLDILNEDFPVLKGNIPVGKPGSG 298
+IDVRDVAKAH++AFQK E I QRL++ FT Q +LDI+NE FP LKG IP GKPG+G
Sbjct: 263 HIDVRDVAKAHILAFQKDELIEQRLMLHAGLFTTQTLLDIINEQFPELKGKIPAGKPGTG 322
Query: 299 ATHNTLGATLDNKKSKKLLGFKFRNLKETIDDTASQILKFE 339
+ L +DN K+KKLLGF+F +LK+ + DT SQIL+ E
Sbjct: 323 NPDDAL-TPVDNSKTKKLLGFEFIDLKKDLYDTISQILEAE 362
>5YWN-A nrPDB
Length = 334
Score = 357 bits (916), Expect = 3e-99, Method: Composition-based stats.
Identities = 153/339 (45%), Positives = 228/339 (67%), Gaps = 8/339 (2%)
Query: 2 SVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKL 61
SVFVSGA G++AQ I+ L+L + YKV+GS RS+EK NL + +G++ FS EVV + +
Sbjct: 4 SVFVSGATGYLAQQIIALVLSKGYKVVGSVRSEEKGANLKKLYGDD--FSYEVVKVLEQK 61
Query: 62 DAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAADSVER 121
AFD +KH ++ I LHTASP F++ D+E+++LIPA+NG K +L SIK A + R
Sbjct: 62 GAFDEALKKH-PEVTIFLHTASPVTFEVEDTEKEILIPAINGTKYVLQSIKD-VAPQITR 119
Query: 122 VVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAAWEFLE 181
VV TSS A+ + + +E SW+ ++E ++ V AY GSK+FAE+AAWEF+E
Sbjct: 120 VVYTSSVVAMSVPEELGSPDVVLSEASWSSLSYEQSKTHGVLAYFGSKQFAERAAWEFVE 179
Query: 182 ENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLSPEDKIPELFGGYID 241
+ + + F L+ VNPVY+FGPQ D++VK LN S E+VNS++ L+ +D +P G +ID
Sbjct: 180 QEKPN--FALSTVNPVYIFGPQAKDEEVKGTLNHSAEMVNSVLKLNKDDDVPATTGTFID 237
Query: 242 VRDVAKAHLVAFQKRETIGQRLIVSEARFTMQDVLDILNEDFPVLKGNIPVGKPGSGATH 301
VRDVAKAHL AF+K E G+RL++S RF Q +LD++ ++FP L +PVGKP S
Sbjct: 238 VRDVAKAHLAAFEKDEAKGERLLLSNTRFNGQTLLDVVRKNFPQLADKLPVGKPHSD--D 295
Query: 302 NTLGATLDNKKSKKLLGFKFRNLKETIDDTASQILKFEG 340
+ ++KK+KK+LGF++ + + ++ D+ Q+LK +G
Sbjct: 296 FSAFKEWNDKKTKKILGFEYFDFETSVVDSIKQVLKVQG 334
>4R1T-A nrPDB
Length = 337
Score = 317 bits (813), Expect = 3e-87, Method: Composition-based stats.
Identities = 100/343 (29%), Positives = 165/343 (48%), Gaps = 36/343 (10%)
Query: 3 VFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAEN--LTEAFGNNPKFSMEVVPDISK 60
V V+GA GFIA +V +LL++ Y V G+ R+ + +N L E G + ++ D+
Sbjct: 13 VCVTGAGGFIASWLVKILLEKGYTVRGTVRNPDDPKNGHLRELEGAKERLTL-CKADLLD 71
Query: 61 LDAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAADSVE 120
+ V HTASP +TD ++ PAV G K ++++ A +V
Sbjct: 72 YQSLREAI----NGCDGVFHTASP----VTDDPEQMVEPAVIGTKNVINA---AAEANVR 120
Query: 121 RVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAAWEFL 180
RVV TSS AV+ M D +E W+ + C++ N YC K AE+AAWE
Sbjct: 121 RVVFTSSIGAVY-MDPNRDPETVVDETCWSDPDF--CKNTK-NWYCYGKMVAEQAAWEEA 176
Query: 181 EENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLSPEDKI-PELFGGY 239
+E +L +NPV V GP + + +N S +++ L +L+ K Y
Sbjct: 177 KEK----GVDLVVINPVLVQGPLL-----QTTVNAS--VLHILKYLTGSAKTYANSVQAY 225
Query: 240 IDVRDVAKAHLVAFQKRETIGQRLIVSEARFTMQDVLDILNEDFPVLKGNIPVGKPGSGA 299
+DV+DVA AH++ ++ E G R + +E+ DV++IL++ FP P+ S
Sbjct: 226 VDVKDVALAHILLYETPEASG-RYLCAESVLHRGDVVEILSKFFPE----YPIPTKCSDV 280
Query: 300 THNTLGATLDNKKSKKLLGFKFRNLKETIDDTASQILKFEGRI 342
T + + + K LG +F +K+ + +T L+ +G +
Sbjct: 281 TKPRVKPYKFSNQKLKDLGLEFTPVKQCLYETVKS-LQEKGHL 322
>2NNL-D nrPDB
Length = 337
Score = 314 bits (805), Expect = 3e-86, Method: Composition-based stats.
Identities = 82/344 (23%), Positives = 142/344 (41%), Gaps = 28/344 (8%)
Query: 2 SVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVV---PDI 58
+V V+GA+GFI +V LL+ Y V + R + + + PK + D+
Sbjct: 7 TVCVTGASGFIGSWLVMRLLERGYTVRATVRDPTNVKKVKHLL-DLPKAETHLTLWKADL 65
Query: 59 SKLDAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAADS 118
+ +FD K V H A+P F+ D E +++ P + G+ GI+ S AA +
Sbjct: 66 ADEGSFDEAI----KGCTGVFHVATPMDFESKDPENEVIKPTIEGMLGIMKSCA--AAKT 119
Query: 119 VERVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAAWE 178
V R+V TSS V + + ++E W+ + + Y SK AE+AAW+
Sbjct: 120 VRRLVFTSSAGTV---NIQEHQLPVYDESCWSDMEFCRAKKMTAWMYFVSKTLAEQAAWK 176
Query: 179 FLEENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLSPEDKIPELFGG 238
+ +EN + + P V GP + + + + H S + G
Sbjct: 177 YAKENN----IDFITIIPTLVVGPFIMSSMPPSLITALSPITGNEAHYSIIRQ-----GQ 227
Query: 239 YIDVRDVAKAHLVAFQKRETIGQRLIVSEARFTMQDVLDILNEDFPVLKGNIPVGKPGSG 298
++ + D+ AH+ F+ + G R I S + D+ +L E +P + G
Sbjct: 228 FVHLDDLCNAHIYLFENPKAEG-RYICSSHDCIILDLAKMLREKYPEYN----IPTEFKG 282
Query: 299 ATHNTLGATLDNKKSKKLLGFKFRNLKETIDDTASQILKFEGRI 342
N +KK LGF+F+ E + A + +G +
Sbjct: 283 VDENLKSVCFSSKKLT-DLGFEFKYSLEDMFTGAVDTCRAKGLL 325
>4R1U-A nrPDB
Length = 349
Score = 312 bits (799), Expect = 1e-85, Method: Composition-based stats.
Identities = 101/344 (29%), Positives = 159/344 (46%), Gaps = 36/344 (10%)
Query: 2 SVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAEN--LTEAFGNNPKFSMEVVPDIS 59
+V V+GA GFIA +V LLL+ Y V G+ R+ E +N L E G + ++ V D+
Sbjct: 29 TVCVTGAGGFIASWLVKLLLERGYTVRGTVRNPEDPKNGHLKELEGARERLTLHKV-DLL 87
Query: 60 KLDAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAADSV 119
L + V V HTASP +TD+ ++L PAVNG K + I A V
Sbjct: 88 DLQSIQSVVH----GCHGVFHTASP----VTDNPDEMLEPAVNGTKNV---IIASAEAKV 136
Query: 120 ERVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAAWEF 179
RVV TSS V+ M + + +E W+ E C++ N YC K AE++AW+
Sbjct: 137 RRVVFTSSIGTVY-MDPNTSRDVVVDESYWSDL--EHCKNTK-NWYCYGKTVAEQSAWDI 192
Query: 180 LEENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLSPEDKI-PELFGG 238
+EN+ + V GP + + +N S ++ L +L+ K
Sbjct: 193 AKENQVDLVVVNPV----VVLGPLL-----QPTINAST--IHILKYLNGAAKTYVNATQS 241
Query: 239 YIDVRDVAKAHLVAFQKRETIGQRLIVSEARFTMQDVLDILNEDFPVLKGNIPVGKPGSG 298
Y+ V+DVA AHL+ ++ G R I E +V++IL + FP P+ S
Sbjct: 242 YVHVKDVALAHLLVYETNSASG-RYICCETALHRGEVVEILAKYFPE----YPLPTKCSD 296
Query: 299 ATHNTLGATLDNKKSKKLLGFKFRNLKETIDDTASQILKFEGRI 342
+ + + + K LG +F +K+ + DT L+ +G +
Sbjct: 297 EKNPRVKPYKFSNQKLKDLGLEFTPVKQCLYDTVRS-LQEKGHL 339
>2P4H-X nrPDB
Length = 322
Score = 296 bits (756), Expect = 1e-80, Method: Composition-based stats.
Identities = 88/346 (25%), Positives = 146/346 (42%), Gaps = 31/346 (8%)
Query: 2 SVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEV---VPDI 58
V V+G GF+ I+ LL+ Y V + R+ + + N P S ++ D+
Sbjct: 3 RVCVTGGTGFLGSWIIKSLLENGYSVNTTIRADPERKRDVSFLTNLPGASEKLHFFNADL 62
Query: 59 SKLDAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAADS 118
S D+F + + HTASP F +++ E + V+G GIL + + +
Sbjct: 63 SNPDSFAAAIE----GCVGIFHTASPIDFAVSEPEEIVTKRTVDGALGILKACVN--SKT 116
Query: 119 VERVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAAWE 178
V+R + TSS +AV K+ D +E W+ Y SK AEKA E
Sbjct: 117 VKRFIYTSSGSAVSFNGKDKD---VLDESDWSDVDLLRSVKPFGWNYAVSKTLAEKAVLE 173
Query: 179 FLEENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLSPEDKIPELFGG 238
F E+N ++ V + P + + V L S E L+ L +++I
Sbjct: 174 FGEQN---------GIDVVTLILPFIVGRFVCPKLPDSIEKALVLV-LGKKEQIGVTRFH 223
Query: 239 YIDVRDVAKAHLVAFQKRETIGQRLIVSEARFTMQDVLDILNEDFPVLKGNIPVGKPGSG 298
+ V DVA+AH+ + G R S ++++ +L+ +P + + V
Sbjct: 224 MVHVDDVARAHIYLLE-NSVPGGRYNCSPFIVPIEEMSQLLSAKYPEYQ-ILTV-----D 276
Query: 299 ATHNTLGATLDNKKSKKLL--GFKFRNLKETIDDTASQILKFEGRI 342
GA L + +KKL+ GF F+ E + D A Q K +G +
Sbjct: 277 ELKEIKGARLPDLNTKKLVDAGFDFKYTIEDMFDDAIQCCKEKGYL 322
>4QUK-A nrPDB
Length = 319
Score = 294 bits (751), Expect = 5e-80, Method: Composition-based stats.
Identities = 98/340 (28%), Positives = 169/340 (49%), Gaps = 30/340 (8%)
Query: 3 VFVSGANGFIAQHIVDLLLKEDYKVIGSAR---SQEKAENLTEAFGNNPKFSMEVVPDIS 59
V V+GA+G+IA +V LLL Y V + R +K ++L + G + + ++
Sbjct: 3 VCVTGASGYIASWLVRLLLHRGYTVKATVRDPNDPKKVDHLVKLDGAKERLQL-FKANLL 61
Query: 60 KLDAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAADSV 119
+ AFD V Q V HTASPF D+ D + +L+ PA+ G +L+S K + S+
Sbjct: 62 EEGAFDSVVQ----GCHGVFHTASPFYHDVKDPQAELIDPALKGTLNVLNSCAK--SPSL 115
Query: 120 ERVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAAWEF 179
+RVVLTSS AAV K + +E + A + C + Y S AE+AAW+F
Sbjct: 116 KRVVLTSSIAAVAYNGKPRTPDVVVDETWFTDADF--CAKSNL-WYVVSATLAEEAAWKF 172
Query: 180 LEENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLSPEDKIPELFGGY 239
++EN ++ +NP V GP + + LNTS + +L++ + P G+
Sbjct: 173 VKENN----IDMVTINPAMVIGPLL-----QPVLNTSAAAILNLINGA--QTFPNASFGW 221
Query: 240 IDVRDVAKAHLVAFQKRETIGQRLIVSEARFTMQDVLDILNEDFPVLKGNIPVGKPGSGA 299
++V+DVA AH++A++ G+ +V E +V+ IL E +P L+ + + +
Sbjct: 222 VNVKDVANAHILAYENASASGRHCLV-ERVAHYSEVVRILRELYPSLQ----LPEKCAD- 275
Query: 300 THNTLGATLDNKKSKKLLGFKFRNLKETIDDTASQILKFE 339
+ +K+ K LG ++ L+ +I +T + + +
Sbjct: 276 DKPYVPIYQVSKEKAKSLGLEYTPLEVSIKETVESLKEKK 315
>3HFS-A nrPDB
Length = 338
Score = 287 bits (733), Expect = 6e-78, Method: Composition-based stats.
Identities = 95/349 (27%), Positives = 156/349 (44%), Gaps = 31/349 (8%)
Query: 2 SVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQE---KAENLTEA--FGNNPKFSMEVVP 56
+ V G GF+A +V LLL++ Y V + R + K +L E G+ F ++
Sbjct: 11 TACVVGGTGFVASLLVKLLLQKGYAVNTTVRDPDNQKKVSHLLELQELGDLKIFRADLTD 70
Query: 57 DISKLDAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAA 116
++S F+ V H A+P F D E D++ PA+ GV ++ + + A
Sbjct: 71 ELS--------FEAPIAGCDFVFHVATPVHFASEDPENDMIKPAIQGVVNVMKACTR--A 120
Query: 117 DSVERVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAA 176
SV+RV+LTSS AAV + + + L +E++W + + P Y SK AEKAA
Sbjct: 121 KSVKRVILTSSAAAV-TINQLDGTGLVVDEKNWTDIEFLTSAKPPTWGYPASKTLAEKAA 179
Query: 177 WEFLEENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLSPEDKIPELF 236
W+F EEN +L V P + G + DV + + L+ L K ++
Sbjct: 180 WKFAEENN----IDLITVIPTLMAGSSL-TSDVPSSIGLAMSLITGNEFLINGMKGMQML 234
Query: 237 GGYI---DVRDVAKAHLVAFQKRETIGQRLIVSEARFTMQDVLDILNEDFPVLKGNIPVG 293
G + V DV +AH+ +K G R I A ++ ++ L++ +P K +P
Sbjct: 235 SGSVSIAHVEDVCRAHIFVAEKESASG-RYICCAANTSVPELAKFLSKRYPQYK--VPTD 291
Query: 294 KPGSGATHNTLGATLDNKKSKKLLGFKFRNLKETIDDTASQILKFEGRI 342
G + ++K K GF F+ E I D + + K +G +
Sbjct: 292 F---GDFPPKSKLIISSEKLVKE-GFSFKYGIEEIYDESVEYFKAKGLL 336
>1ZZE-A nrPDB
Length = 342
Score = 274 bits (700), Expect = 4e-74, Method: Composition-based stats.
Identities = 96/341 (28%), Positives = 151/341 (44%), Gaps = 24/341 (7%)
Query: 3 VFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNN--PKFSMEVVPDISK 60
V V+GANGF+A H+V+ LL+ YKV G+ARS K NL + + +F VV D+ K
Sbjct: 14 VLVTGANGFVASHVVEQLLEHGYKVRGTARSASKLANLQKRWDAKYPGRFETAVVEDMLK 73
Query: 61 LDAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAADSVE 120
A+D V K V H AS F ++ +++ PA+ G L + A SV+
Sbjct: 74 QGAYDEVI----KGAAGVAHIASVVSF--SNKYDEVVTPAIGGTLNALRA--AAATPSVK 125
Query: 121 RVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPV-------NAYCGSKKFAE 173
R VLTSS + + K N + + +E+SWN + + ++ P Y SK AE
Sbjct: 126 RFVLTSSTVSAL-IPKPNVEGIYLDEKSWNLESIDKAKTLPESDPQKSLWVYAASKTEAE 184
Query: 174 KAAWEFLEENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLSPEDKIP 233
AAW+F++EN+ F L AV P Y G +FD + + + + +SP +
Sbjct: 185 LAAWKFMDENKP--HFTLNAVLPNYTIG-TIFDPETQSGSTSGWMMSLFNGEVSPALALM 241
Query: 234 ELFGGYIDVRDVAKAHLVAFQKRETIGQRLIVSEARFTMQDVLDILNEDFPVLKGNIPVG 293
Y+ D+ HL + +R+ + F VL + +P P
Sbjct: 242 PP-QYYVSAVDIGLLHLGCLVLPQIERRRVYGTAGTFDWNTVLATFRKLYP--SKTFPAD 298
Query: 294 KPGSGATHNTLGATLDNKKSKKLLGFKFRNLKETIDDTASQ 334
P G + + K L +R+++E+I D
Sbjct: 299 FPDQGQDLSKFDTAPSLEILKSLGRPGWRSIEESIKDLVGS 339
>1GY8-A nrPDB
Length = 397
Score = 202 bits (513), Expect = 2e-52, Method: Composition-based stats.
Identities = 82/392 (20%), Positives = 158/392 (40%), Gaps = 80/392 (20%)
Query: 1 MSVFVSGANGFIAQHIVDLLLKE-DYKVI---------GSARSQEKAEN----LTEAFGN 46
M V V G G+I H V LL++ ++ V+ G + E EN L ++ G
Sbjct: 3 MRVLVCGGAGYIGSHFVRALLRDTNHSVVIVDSLVGTHGKSDHVETRENVARKLQQSDGP 62
Query: 47 NP----KFSMEVVPDISKLDAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVN 102
P +++ V D+ D + VF +HG I V+H + + +S RD L N
Sbjct: 63 KPPWADRYAALEVGDVRNEDFLNGVFTRHGP-IDAVVHMCA--FLAVGESVRDPLKYYDN 119
Query: 103 GVKGILHSIKKYAADSVERVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPV 162
V GIL ++ ++++ +SS AA+F S++ N E + + + P
Sbjct: 120 NVVGILRLLQAMLLHKCDKIIFSSS-AAIF--GNPTMGSVSTNAEPID----INAKKSPE 172
Query: 163 NAYCGSKKFAEKAAWEFLEENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNS 222
+ Y SK AE+ + + ++ + + G D D+ +H S L+
Sbjct: 173 SPYGESKLIAER----MIRDCAEAYGIKGICLRYFNACGAHE-DGDIGEHYQGSTHLIPI 227
Query: 223 LM-----HLSPE-----------DKIPELFGG------------YIDVRDVAKAHLVAFQ 254
++ ++P+ DK +FG Y+ V D+A AH++A
Sbjct: 228 ILGRVMSDIAPDQRLTIHEDASTDKRMPIFGTDYPTPDGTCVRDYVHVCDLASAHILALD 287
Query: 255 KRETIG----QRL-----IVSEARFTMQDVLDILNEDFPVLKGNIPVGKPGSGATHNTLG 305
E +G + + + +++++V+++ + IPV + G
Sbjct: 288 YVEKLGPNDKSKYFSVFNLGTSRGYSVREVIEVARK---TTGHPIPVRECGRREGDPAYL 344
Query: 306 ATLDNKKSKKLLGFKFRNLKETIDDTASQILK 337
+ K++++LG ++ DT I++
Sbjct: 345 VAASD-KAREVLG--WKPK----YDTLEAIME 369
>4WKG-A nrPDB
Length = 660
Score = 169 bits (427), Expect = 2e-42, Method: Composition-based stats.
Identities = 65/305 (21%), Positives = 120/305 (39%), Gaps = 59/305 (19%)
Query: 2 SVFVSGANGFIAQHIVDLLLKED-YKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISK 60
V + G NGFI H+ + LL+ED Y+V G + + F N+P F V DIS
Sbjct: 317 RVLILGVNGFIGNHLTERLLREDHYEVYG----LDIGSDAISRFLNHPHFHF-VEGDISI 371
Query: 61 LDAFDHVFQKHGKDIKIVL----------HTASPFCFDITDSERDLLIPAVNGVKGILHS 110
+ + H K +VL +T +P D E +L
Sbjct: 372 HSEW---IEYHVKKCDVVLPLVAIATPIEYTRNPLRVFELDFEENL-------------R 415
Query: 111 IKKYAADSVERVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKK 170
I +Y +R++ S+ + V+ M + F+E+ N + P Y SK+
Sbjct: 416 IIRYCVKYRKRIIFPST-SEVYGMCSDK----YFDEDHSNLIVGPV--NKPRWIYSVSKQ 468
Query: 171 FAEKAAWEFLEENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLSPED 230
++ W + E+ + T P GP++ + + + + +S + +++L
Sbjct: 469 LLDRVIWAYGEKE----GLQFTLFRPFNWMGPRLDNLNAAR-IGSSRAITQLILNLVEGS 523
Query: 231 KIPELFGG-----YIDVRDVAKAHLVAFQKRETIGQRLIVS-------EARFTMQDVLDI 278
I + GG + D+RD +A ++ E G R E +++++ ++
Sbjct: 524 PIKLIDGGKQKRCFTDIRDGIEA---LYRIIENAGNRCDGEIINIGNPENEASIEELGEM 580
Query: 279 LNEDF 283
L F
Sbjct: 581 LLASF 585
>4LIS-A nrPDB
Length = 371
Score = 156 bits (395), Expect = 1e-38, Method: Composition-based stats.
Identities = 71/344 (20%), Positives = 117/344 (34%), Gaps = 49/344 (14%)
Query: 2 SVFVSGANGFIAQHIVDLLLKEDYKVIGS---ARSQEKAENLTEAF-GNNPKFSMEVVPD 57
SV V+G G+I LL+ YKV+ + S +A N E G +F+ D
Sbjct: 5 SVLVTGGTGYIGSFTTLALLEAGYKVVVADNLYNSSAEALNRIELISGKKAEFAQL---D 61
Query: 58 ISKLDAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAAD 117
++ AFD VF+ H DI V+H A+ E+ L VN V G + ++
Sbjct: 62 VTDEAAFDKVFEAH-PDIDSVIHFAALKAVG-ESGEKPLDYYHVN-VYGTICLLRSMVRH 118
Query: 118 SVERVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAAW 177
+V +V +SS A V+ A + E C P N Y +K E A
Sbjct: 119 NVTNIVFSSS-ATVYGDATRFPDMIPIPEH---------CPLGPTNPYGNTKFAIELAIT 168
Query: 178 EFLEENRDS----------VKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLS 227
+ + R++ K+ + G + L+ L ++
Sbjct: 169 DVINAQRNNAKKAGNETEAAKWNGALLRYFNPAGAHPSGIMGEDPQGVPYNLLPLLAQVA 228
Query: 228 PEDKIPELFGG-------------YIDVRDVAKAHLVAFQKRET--IGQRLIVSEARFTM 272
+ L G YI + D+A HL A G R +
Sbjct: 229 TGKREKLLVFGDDYASHDGTAIRDYIHILDLADGHLKALNYLRANNPGVRAW-NLGTGRG 287
Query: 273 QDVLDILNEDFPVLKGNIP---VGKPGSGATHNTLGATLDNKKS 313
V +++ + ++P + + T T N +
Sbjct: 288 STVYEMIRAFSKAVGRDLPYEVAPRRAGDVLNLTSNPTRANTEL 331
>1UDA-A nrPDB
Length = 338
Score = 121 bits (304), Expect = 4e-28, Method: Composition-based stats.
Identities = 73/340 (21%), Positives = 112/340 (32%), Gaps = 37/340 (10%)
Query: 1 MSVFVSGANGFIAQHIVDLLLKEDYKVI---GSARSQEKAENLTEAF-GNNPKFSMEVVP 56
M V V+G +G+I H LL+ + VI S+ + E G +P F V
Sbjct: 1 MRVLVTGGSGYIGSHTCVQLLQNGHDVIILDNLCNSKRSVLPVIERLGGKHPTF---VEG 57
Query: 57 DISKLDAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAA 116
DI + H I V+H A + +S + L N V G L I A
Sbjct: 58 DIRNEALMTEILHDHA--IDTVIHFAGLK--AVGESVQKPLEYYDNNVNGTLRLISAMRA 113
Query: 117 DSVERVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAA 176
+V+ + +SS A V+ + +F P + Y SK E+
Sbjct: 114 ANVKNFIFSSS-ATVYGDNPKIPYVESFP------------TGTPQSPYGKSKLMVEQIL 160
Query: 177 WEFLEENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLSPED------ 230
+ + D L NPV +D + N + + +
Sbjct: 161 TDLQKAQPDWSIALLRYFNPVGAHPSGDMGEDPQGIPNNLMPYIAQVAVGRRDSLAIFGN 220
Query: 231 KIPELFGG----YIDVRDVAKAHLVAFQKRETIGQRLIVSEARFTMQDVLDILNEDFPVL 286
P G YI V D+A H+VA +K I + VLD++N
Sbjct: 221 DYPTEDGTGVRDYIHVMDLADGHVVAMEKLANKPGVHIYNLGAGVGNSVLDVVNAFSKAC 280
Query: 287 KGNIPVGKPGSGATHNTLGATLDNKKSKKLLGFKFRNLKE 326
PV + L A + SK +R +
Sbjct: 281 GK--PVNYHFAPRREGDLPAYWADA-SKADRELNWRVTRT 317
>1Z45-A nrPDB
Length = 699
Score = 116 bits (291), Expect = 1e-26, Method: Composition-based stats.
Identities = 54/270 (20%), Positives = 93/270 (34%), Gaps = 30/270 (11%)
Query: 3 VFVSGANGFIAQHIVDLLLKEDYK-VIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKL 61
V V+G G+I H V L++ Y V+ S +++ D+
Sbjct: 14 VLVTGGAGYIGSHTVVELIENGYDCVVADNLSNSTYDSVARLEVLTKHHIPFYEVDLCDR 73
Query: 62 DAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAADSVER 121
+ VF+++ I V+H A + +S + L N + G + ++ +V +
Sbjct: 74 KGLEKVFKEY--KIDSVIHFAGLK--AVGESTQIPLRYYHNNILGTVVLLELMQQYNVSK 129
Query: 122 VVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAAWEFLE 181
V +SS A V+ A + EE C P N Y +K E +
Sbjct: 130 FVFSSS-ATVYGDATRFPNMIPIPEE---------CPLGPTNPYGHTKYAIENILNDLYN 179
Query: 182 ENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLSPEDKIPELFGG--- 238
++ S KF + G + L L+ + ++ + G
Sbjct: 180 SDKKSWKFA--ILRYFNPIGAHPSGLIGEDPLGIPNNLLPYMAQVAVGRREKLYIFGDDY 237
Query: 239 ----------YIDVRDVAKAHLVAFQKRET 258
YI V D+AK H+ A Q E
Sbjct: 238 DSRDGTPIRDYIHVVDLAKGHIAALQYLEA 267
>2C20-A nrPDB
Length = 330
Score = 105 bits (262), Expect = 2e-23, Method: Composition-based stats.
Identities = 62/339 (18%), Positives = 116/339 (34%), Gaps = 49/339 (14%)
Query: 2 SVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKL 61
S+ + G G+I H V L+ E V+ + + G D+
Sbjct: 3 SILICGGAGYIGSHAVKKLVDEGLSVVV-VDNLQTGHEDAITEGAK-----FYNGDLRDK 56
Query: 62 DAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAADSVER 121
VF + +I+ V+H A+ ++ L N V G L ++ V++
Sbjct: 57 AFLRDVFTQE--NIEAVMHFAADSLVGVS--MEKPLQYYNNNVYGALCLLEVMDEFKVDK 112
Query: 122 VVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAAWEFLE 181
+ SS AA + E D L E N P N Y +K EK + +
Sbjct: 113 FIF-SSTAATYG---EVDVDLITEETMTN----------PTNTYGETKLAIEKMLHWYSQ 158
Query: 182 ENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLSPEDKIPELFGG--- 238
+ K V G + + + L+ ++ ++ + + G
Sbjct: 159 ASNLRYKI----FRYFNVAGAT-PNGIIGEDHRPETHLIPLVLQVALGQREKIMMFGDDY 213
Query: 239 ----------YIDVRDVAKAHLVAFQKRETIGQR--LIVSEAR-FTMQDVLDILNEDFPV 285
YI V D+ AH + + + G+ + F++++++D + E V
Sbjct: 214 NTPDGTCIRDYIHVEDLVAAHFLGLKDLQNGGESDFYNLGNGNGFSVKEIVDAVRE---V 270
Query: 286 LKGNIPVGKPGSGATHNTLGATLDNKKSKKLLGFKFRNL 324
IP A ++K+K+ LG+ R +
Sbjct: 271 TNHEIPAEVAPRRAGDPARLVA-SSQKAKEKLGWDPRYV 308
>3ENK-A nrPDB
Length = 341
Score = 105 bits (262), Expect = 2e-23, Method: Composition-based stats.
Identities = 59/295 (20%), Positives = 103/295 (34%), Gaps = 35/295 (11%)
Query: 2 SVFVSGANGFIAQHIVDLLLKEDYKVIGSAR----SQEKAENLTEAFGNNPKFSMEVVPD 57
++ V+G G+I H LL Y V+ + +E + + G P F D
Sbjct: 7 TILVTGGAGYIGSHTAVELLAHGYDVVIADNLVNSKREAIARIEKITGKTPAFH---ETD 63
Query: 58 ISKLDAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAAD 117
+S A +F H I +H A+ + +S + N + +L ++
Sbjct: 64 VSDERALARIFDAH--PITAAIHFAALK--AVGESVAKPIEYYRNNLDSLLSLLRVMRER 119
Query: 118 SVERVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAAW 177
+V+R+V +SS A V+ + + + +E N Y +K AE+
Sbjct: 120 AVKRIVFSSS-ATVYGVPERSP----IDETF---------PLSATNPYGQTKLMAEQILR 165
Query: 178 EFLEENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVN--SLMHLSP----EDK 231
+ + L NPV + +D N V ++ L
Sbjct: 166 DVEAADPSWRVATLRYFNPVGAHESGLIGEDPAGIPNNLMPYVAQVAVGKLEKLRVFGSD 225
Query: 232 IPELFGG----YIDVRDVAKAHLVAFQKRETIGQRLIVSEARFTMQDVLDILNED 282
P G YI V D+A+ H+ A E L V+ VL+++
Sbjct: 226 YPTPDGTGVRDYIHVVDLARGHIAALDALERRDASLTVNLGTGRGYSVLEVVRAF 280
>1I3M-A nrPDB
Length = 348
Score = 104 bits (260), Expect = 4e-23, Method: Composition-based stats.
Identities = 68/312 (21%), Positives = 108/312 (34%), Gaps = 46/312 (14%)
Query: 3 VFVSGANGFIAQHIVDLLLKEDY----------KVIGSARSQEKAENLTEAFGNNPKFSM 52
V V+G G+I H V LL+ Y G E + E G + +F
Sbjct: 5 VLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRSVEFEE 64
Query: 53 EVVPDISKLDAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIK 112
DI A +F+K+ V+H A ++ L VN G + ++
Sbjct: 65 M---DILDQGALQRLFKKY--SFMAVIHFAGLKAMG-ESVQKPLDYYRVNLT-GTIQLLE 117
Query: 113 KYAADSVERVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFA 172
A V+ +V +SS A V+ N + L +E N Y SK F
Sbjct: 118 IMKAHGVKNLVFSSS-ATVYG----NPQYLPLDEAHPT--------GGCTNPYGKSKFFI 164
Query: 173 EKAAWEFLEENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLSPEDKI 232
E+ + + ++ L NP +D + N V+ + +
Sbjct: 165 EEMIRDLCQADKTWNVVLLRYFNPTGAHASGCIGEDPQGIPNNLMPYVSQVA--IGRREA 222
Query: 233 PELFGG------------YIDVRDVAKAHLVAFQK-RETIGQRLIVSEARFTMQDVLDIL 279
+FG YI V D+AK H+ A +K +E G R+ + T VL ++
Sbjct: 223 LNVFGNDYDTEDGTGVRDYIHVVDLAKGHIAALRKLKEQCGCRIY-NLGTGTGYSVLQMV 281
Query: 280 NEDFPVLKGNIP 291
IP
Sbjct: 282 QAMEKASGKKIP 293
>4WOK-A nrPDB
Length = 336
Score = 103 bits (257), Expect = 1e-22, Method: Composition-based stats.
Identities = 60/343 (17%), Positives = 112/343 (32%), Gaps = 44/343 (12%)
Query: 3 VFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKLD 62
V V G GFI H LL + Y + + +G+ V DI
Sbjct: 14 VLVVGGAGFIGSHTAKLLAGQGYAPVV-YDNLSTGHQSAVRWGDF------VEGDILDQA 66
Query: 63 AFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAADSVERV 122
+K+ V+H A+ + +S D N V G + + V
Sbjct: 67 RLVETMEKYAP--VAVIHFAASAY--VGESVEDPAKYYRNNVGGTQSLLDACRLTRTQNV 122
Query: 123 VLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAAWEFLEE 182
+ +SS A + + E +P+N Y +K AE ++
Sbjct: 123 IFSSSCAT-YGVPSR-------------LPIGEGEAQNPINPYGRTKLIAEHMLADYA-- 166
Query: 183 NRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLSPEDKIPELFG----- 237
+ A+ G + + +KH + + ++M + + E++G
Sbjct: 167 --VAYGLRYVALRYFNASGADIDGELGEKHDPETHLIPRAMMAAAGRLDVLEVYGDDYET 224
Query: 238 -------GYIDVRDVAKAHLVAFQKRETIGQRLIVSEARFTMQDVLDILNEDFPVLKGNI 290
YI V D+A+AH++A + + G L V+ + +I+ + ++
Sbjct: 225 PDGTCIRDYIHVTDLARAHVLAVEHLKEAGGNLAVNLGTGRGTSIREIVQSIGRLTGRSV 284
Query: 291 PVGKPGSGATHNTLGATLDNKKSKKLLGFKFRNLKETIDDTAS 333
PV A ++KL F + +D
Sbjct: 285 PVAMRARRAGDPPALYADPALAAEKL---GFHTVYSDLDTIIR 324
>1BXK-A nrPDB
Length = 355
Score = 84.2 bits (206), Expect = 7e-17, Method: Composition-based stats.
Identities = 56/298 (18%), Positives = 102/298 (34%), Gaps = 22/298 (7%)
Query: 3 VFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEA--FGNNPKFSMEVVPDISK 60
+ ++G GFI +V ++ E + A NL + +F+ E V DI
Sbjct: 4 ILITGGAGFIGSALVRYIINETSDAVVVVDKLTYAGNLMSLAPVAQSERFAFEKV-DICD 62
Query: 61 LDAFDHVFQKHGKDIKIVLHTASPFCFDIT-DSERDLLIPAVNGVKGILHSIKKYAADSV 119
VF +H D V+H A+ D + D + + G +L + + Y
Sbjct: 63 RAELARVFTEHQPDC--VMHLAAESHVDRSIDGPAAFIETNIVGTYTLLEAARAYWNA-- 118
Query: 120 ERVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAAWEF 179
LT + F + + + S + E+ P + Y SK ++ +
Sbjct: 119 ----LTEDKKSAFRFHHISTDEVYGDLHSTDDFFTETTPYAPSSPYSASKASSDHLVRAW 174
Query: 180 LEENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLSPEDKIPELFGGY 239
L + N +GP F + + + + SL +I + +
Sbjct: 175 LR----TYGLPTLITNCSNNYGPYHFPEKLIPLMILNALAGKSLPVYGNGQQIRD----W 226
Query: 240 IDVRDVAKAHLVAFQKRETIGQRLIVSEARFTMQ-DVLDILNEDFPVLKGNIPVGKPG 296
+ V D A+A L +G+ + DV++ + E L N P G
Sbjct: 227 LYVEDHARA-LYCVATTGKVGETYNIGGHNERKNLDVVETICELLEELAPNKPHGVAH 283
>4EJ0-A nrPDB
Length = 342
Score = 81.1 bits (198), Expect = 7e-16, Method: Composition-based stats.
Identities = 45/290 (15%), Positives = 87/290 (30%), Gaps = 46/290 (15%)
Query: 1 MSVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISK 60
M++ V+GA GFI ++V L + I + + +A+ + D
Sbjct: 13 MTLIVTGAAGFIGANLVKALNERGETRIIAVDNLTRADKFKNLVD-------CEIDDYLD 65
Query: 61 LDAFDHVF-QKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAADSV 119
F F + ++ V H + TD ++ ++
Sbjct: 66 KTEFVERFARGDFGKVRAVFHEGACSDTMETDG-----RYMMDNNFRYSRAVLDACLAQG 120
Query: 120 ERVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAAWEF 179
+ + SS AA++ + + P+N Y SK ++
Sbjct: 121 AQFLYASS-AAIYGGSSRFVEEREVEA--------------PLNVYGYSKFLFDQVIRRV 165
Query: 180 LEENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLSPEDKI------- 232
+ K ++ V+GP+ + K S N +
Sbjct: 166 M----PGAKSQIAGFRYFNVYGPR----ESHKGRMASVAFHNFNQFRAEGKVKLFGEYSG 217
Query: 233 ---PELFGGYIDVRDVAKAHLVAFQKRETIGQRLIVSEARFTMQDVLDIL 279
E ++ V DVAK +L F E G + + D+ +
Sbjct: 218 YGPGEQTRDFVSVEDVAKVNLYFFDHPEKSGIFNLGTGRAQPFNDIAATV 267
>2Q1W-A nrPDB
Length = 333
Score = 79.6 bits (194), Expect = 2e-15, Method: Composition-based stats.
Identities = 59/327 (18%), Positives = 114/327 (34%), Gaps = 43/327 (13%)
Query: 3 VFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKLD 62
VF++G G I HI +LLL+ KV+G + E ++P + V I+
Sbjct: 24 VFITGICGQIGSHIAELLLERGDKVVG-IDNFATG--RREHLKDHPNLTF-VEGSIADHA 79
Query: 63 AFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAADSVERV 122
+ + V+HTA+ + D D D L V G + ++ ++V R
Sbjct: 80 LVNQLIGDLQP--DAVVHTAASYK-DPDDWYNDTLTNCVGGS----NVVQAAKKNNVGRF 132
Query: 123 VLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAAWEFLEE 182
V + A + + + ++ ++Y SK E ++LE
Sbjct: 133 VYFQT-ALCYGVKPIQQP-----------VRLDHPRNPANSSYAISKSANE----DYLE- 175
Query: 183 NRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLSPEDKIPELFGGYIDV 242
+ V GP+ + E + + + ++ V
Sbjct: 176 ---YSGLDFVTFRLANVVGPRNVSGPLPIFFQRLSE--------GKKCFVTKARRDFVFV 224
Query: 243 RDVAKAHLVAFQKRETIGQRLIVSEARFTMQDVLDILNEDFPVLKGNIPVGKPGSGATHN 302
+D+A+A + A G S ++++ D + E + P + +
Sbjct: 225 KDLARATVRAVDGV-GHGAYHFSSGTDVAIKELYDAVVEAMALPS--YPEPEIRELGPDD 281
Query: 303 TLGATLDNKKSKKLLG-FKFRNLKETI 328
LD ++ + G +F LKET+
Sbjct: 282 APSILLDPSRTIQDFGKIEFTPLKETV 308
>6BWL-A nrPDB
Length = 328
Score = 76.9 bits (187), Expect = 1e-14, Method: Composition-based stats.
Identities = 36/207 (17%), Positives = 71/207 (34%), Gaps = 22/207 (10%)
Query: 1 MSVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISK 60
M + V+G GFI + +V LL++ ++V F ++ + DI
Sbjct: 1 MKILVTGGAGFIGRWVVKRLLQDKHEVWILDNLANSTTANITEFAHDLNLKQCIQGDIKD 60
Query: 61 LDAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAADSVE 120
+F+ + H A+ ++ DS D N G + +++ V+
Sbjct: 61 KKLVAQLFEN--NSFDLCYHLAA--SINVQDSIDDARATFENDTIGTFNLLEQCLNYDVK 116
Query: 121 RVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAAWEFL 180
+V S+ + +++ + E P + Y GSK AE +
Sbjct: 117 -MVFMSTC-------------MVYDKATNIQGISELDPIKPASPYAGSKIAAENMVLSYY 162
Query: 181 EENRDSVKFELTAVNPVYVFGPQMFDK 207
+ K + + P +GP
Sbjct: 163 ----YAYKLPVVVIRPFNTYGPFQKTG 185
>2PK3-A nrPDB
Length = 321
Score = 72.6 bits (176), Expect = 2e-13, Method: Composition-based stats.
Identities = 64/344 (18%), Positives = 127/344 (36%), Gaps = 49/344 (14%)
Query: 1 MSVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISK 60
M ++G GF+ +++ + L +++ +V G++R+ E P M + DI
Sbjct: 13 MRALITGVAGFVGKYLANHLTEQNVEVFGTSRNNE---------AKLPNVEM-ISLDIMD 62
Query: 61 LDAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAADSVE 120
V + H A+ + DS + V G LH + +++
Sbjct: 63 SQRVKKVISDIKP--DYIFHLAAKSS--VKDSWLNKKGTFSTNVFGTLHVLDAVRDSNLD 118
Query: 121 RVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAAWEFL 180
+LT + + M EES E Q P++ Y SK A +++
Sbjct: 119 CRILTIGSSEEYGM--------ILPEES---PVSEENQLRPMSPYGVSKASVGMLARQYV 167
Query: 181 EENRDSVKFELTAVNPVYVFGP-----QMFDKDVKKHLNTSCELVNSLMHLSPEDKIPEL 235
+ ++ GP + K+ ++ E ++ + + + +
Sbjct: 168 KA----YGMDIIHTRTFNHIGPGQSLGFVTQDFAKQIVDIEMEKQEPIIKVGNLEAVRD- 222
Query: 236 FGGYIDVRDVAKAHLVAFQKRETIGQRLIVSEAR-FTMQDVLDILNEDFPVLKGNIPVGK 294
+ DVRD+ +A+ + Q +T G V +QDVLD+L N+ +
Sbjct: 223 ---FTDVRDIVQAYWLLSQYGKT-GDVYNVCSGIGTRIQDVLDLLLAM-----ANVKIDT 273
Query: 295 PGSG-ATHNTLGATL--DNKKSKKLLGFKFR-NLKETIDDTASQ 334
+ + TL NK+ K G+K R L++++ +
Sbjct: 274 ELNPLQLRPSEVPTLIGSNKRLKDSTGWKPRIPLEKSLFEILQS 317
>1R66-A nrPDB
Length = 337
Score = 72.6 bits (176), Expect = 3e-13, Method: Composition-based stats.
Identities = 49/293 (16%), Positives = 91/293 (31%), Gaps = 50/293 (17%)
Query: 1 MSVFVSGANGFIAQHIVDLLLKEDYK--------VIGSARSQEKAENLTEAFGNNPKFSM 52
M + V+G GFI H V LL Y V+ S NL + P+
Sbjct: 1 MRLLVTGGAGFIGSHFVRQLLAGAYPDVPADEVIVLDSLTYAGNRANLAPVDAD-PRLRF 59
Query: 53 EVVPDISKLDAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIK 112
V DI + + + ++H A+ D + + + V+G ++
Sbjct: 60 -VHGDIRDAGLLA----RELRGVDAIVHFAAESHVDRSIAGASVFTET--NVQGTQTLLQ 112
Query: 113 KYAADSVERVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFA 172
V RVV S+ V+ + + SW ES +P + Y SK +
Sbjct: 113 CAVDAGVGRVVHVSTD-EVYG---------SIDSGSWT----ESSPLEPNSPYAASKAGS 158
Query: 173 EKAAWEFLEENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLSPEDKI 232
+ A + + ++ +GP +L+ + +
Sbjct: 159 DLVARAYHR----TYGLDVRITRCCNNYGP----------YQHPEKLIPLFVTNLLDGGT 204
Query: 233 PELFG------GYIDVRDVAKAHLVAFQKRETIGQRLIVSEARFTMQDVLDIL 279
L+G ++ D + + I T +++ IL
Sbjct: 205 LPLYGDGANVREWVHTDDHCRGIALVLAGGRAGEIYHIGGGLELTNRELTGIL 257
>2Q1T-A nrPDB
Length = 377
Score = 71.1 bits (172), Expect = 6e-13, Method: Composition-based stats.
Identities = 58/343 (16%), Positives = 114/343 (33%), Gaps = 33/343 (9%)
Query: 3 VFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKLD 62
V V G GF+ ++V LL+ + + AE + +FS + D
Sbjct: 35 VMVVGGAGFVGSNLVKRLLELGVNQVHVVDNLLSAEKINVPDHPAVRFSETSITD----- 89
Query: 63 AFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAA-DSVER 121
D + + V H A+ S D L N L ++ +++
Sbjct: 90 --DALLASLQDEYDYVFHLAT--YHGNQSSIHDPLADHENNTLTTLKLYERLKHFKRLKK 145
Query: 122 VVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAAWEFLE 181
VV +++ ++ TF++ T + + Y SK F E + + +
Sbjct: 146 VVYSAAGCSIA--------EKTFDDAKATEETDIVSLHNNDSPYSMSKIFGEFYSVYYHK 197
Query: 182 ENR-DSVKFEL-TAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLSPEDKIPELFGG- 238
+++ +V+ P + G + + +P GG
Sbjct: 198 QHQLPTVRARFQNVYGPGEILGAGRWRGTPATVWRNVTP--TFIYKALKGMPLPLENGGV 255
Query: 239 ----YIDVRDVAKAHLVAFQKRETIGQRLIVSEARFTMQDVLDILNEDFPVLKGNIPVGK 294
+I V DVA + G I S ++ D+ +NE + K
Sbjct: 256 ATRDFIFVEDVANGLIACAADGTPGGVYNIASGKETSIADLATKINEITGNNTELDRLPK 315
Query: 295 PGSGATHNTLGATLDNKKSKKLLGFKFRNLKETIDDTASQILK 337
+ G+ +K+++ LGF + +IDD + ++
Sbjct: 316 RPWDNSGKRFGSP---EKARRELGF---SADVSIDDGLRKTIE 352
>1EQ2-A nrPDB
Length = 310
Score = 66.5 bits (160), Expect = 2e-11, Method: Composition-based stats.
Identities = 43/319 (13%), Positives = 88/319 (27%), Gaps = 43/319 (13%)
Query: 3 VFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKLD 62
+ V+G GFI +IV L + I + + + + + K D
Sbjct: 2 IIVTGGAGFIGSNIVKALNDKGITDILVVDNLKDGTKFVNLV------DLNIADYMDKED 55
Query: 63 AFDHVFQKHG-KDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAADSVER 121
+ D++ + H + D ++ + Y +
Sbjct: 56 FLIQIMAGEEFGDVEAIFHEGACSSTTEWDG-----KYMMDNNYQYSKELLHYCLEREIP 110
Query: 122 VVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAAWEFLE 181
+ SS A + +S + P+N Y SK + E++
Sbjct: 111 FLYASSAATYGGRTSDFIESREYE--------------KPLNVYGYSKFLFD----EYVR 152
Query: 182 ENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLSPEDKIPELFGG--- 238
+ ++ V+GP+ + K S + L+ + G
Sbjct: 153 QILPEANSQIVGFRYFNVYGPR----EGHKGSMASVAF-HLNTQLNNGESPKLFEGSENF 207
Query: 239 ---YIDVRDVAKAHLVAFQKRETIGQRLIVSEARFTMQDVLDILNEDFPVLKGNIPVGKP 295
++ V DVA +L + G + + + Q V D + + P
Sbjct: 208 KRDFVYVGDVADVNLWFLE-NGVSGIFNLGTGRAESFQAVADATLAYHKKGQIEY-IPFP 265
Query: 296 GSGATHNTLGATLDNKKSK 314
D +
Sbjct: 266 DKLKGRYQAFTQADLTNLR 284
>1KEU-A nrPDB
Length = 361
Score = 66.1 bits (159), Expect = 2e-11, Method: Composition-based stats.
Identities = 58/345 (16%), Positives = 112/345 (32%), Gaps = 42/345 (12%)
Query: 1 MSVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEA--FGNNPKFSMEVVPDI 58
M + ++G GFI +V ++K + + A NL + +++ E DI
Sbjct: 1 MKILITGGAGFIGSAVVRHIIKNTQDTVVNIDKLTYAGNLESLSDISESNRYNFE-HADI 59
Query: 59 SKLDAFDHVFQKHGKDIKIVLHTASPFCFDIT-DSERDLLIPAVNGVKGILHSIKKY--- 114
+F+++ V+H A+ D + + + G +L +KY
Sbjct: 60 CDSAEITRIFEQYQP--DAVMHLAAESHVDRSITGPAAFIETNIVGTYALLEVARKYWSA 117
Query: 115 -AADSVERVVLTS-SYAAVFDMAKENDKSLTFNEESWNPATW-ESCQSDPVNAYCGSKKF 171
D S V+ D+ E S + E+ P + Y SK
Sbjct: 118 LGEDKKNNFRFHHISTDEVYGDLPHPDEV----ENSVTLPLFTETTAYAPSSPYSASKAS 173
Query: 172 AEKAAWEFLEENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLSPEDK 231
++ + R + N +GP F + + + + L D+
Sbjct: 174 SDH----LVRAWRRTYGLPTIVTNCSNNYGPYHFPEKLIPLVILNALEGKPLPIYGKGDQ 229
Query: 232 IPELFGGYIDVRDVAKAHLVAFQKRETIGQRLIVSEARFTMQ-----DVLDILNEDFPVL 286
I + ++ V D A+A L G+ + + D+L+E P
Sbjct: 230 IRD----WLYVEDHARA-LHMVVTEGKAGETYNIGGHNEKKNLDVVFTICDLLDEIVPKA 284
Query: 287 -----KGNIPVGKPGSGATHNTLGATLDNKKSKKLLGFKFRNLKE 326
+ +PG +D K + LG ++ L+
Sbjct: 285 TSYREQITYVADRPGHD-----RRYAIDAGKISRELG--WKPLET 322
>1WVG-A nrPDB
Length = 359
Score = 64.9 bits (156), Expect = 5e-11, Method: Composition-based stats.
Identities = 39/205 (19%), Positives = 67/205 (32%), Gaps = 22/205 (10%)
Query: 2 SVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKL 61
VFV+G GF + L + V G A +L E + DI
Sbjct: 11 RVFVTGHTGFKGSWLSLWLTEMGAIVKGYALDAPTVPSLFEIV-RLNDLMESHIGDIRDF 69
Query: 62 DAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAADSVER 121
+ + +I V H A+ ++ + V G +H + ++V++
Sbjct: 70 EKLRSSIAEFKPEI--VFHMAAQPLVRLS--YEQPIKTYSTNVMGTVHLL-----ETVKQ 120
Query: 122 VVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAAWEFLE 181
V + AV ++ + ++ W E+ + Y SK AE A F
Sbjct: 121 V---GNIKAVVNITSDK----CYDNREWVWGYRENEPMGGYDPYSNSKGCAELVASAFRN 173
Query: 182 -----ENRDSVKFELTAVNPVYVFG 201
N + L +V V G
Sbjct: 174 SFFNPANYEQHGVGLASVRAGNVIG 198
>2X86-A nrPDB
Length = 357
Score = 63.8 bits (153), Expect = 9e-11, Method: Composition-based stats.
Identities = 42/319 (13%), Positives = 88/319 (27%), Gaps = 43/319 (13%)
Query: 3 VFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKLD 62
+ V+G GFI +IV L + I + + + + + K D
Sbjct: 49 IIVTGGAGFIGSNIVKALNDKGITDILVVDNLKDGTKFVNLV------DLNIADYMDKED 102
Query: 63 AFDHVFQKHG-KDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAADSVER 121
+ D++ + H + D ++ + Y +
Sbjct: 103 FLIQIMAGEEFGDVEAIFHEGACSSTTEWDG-----KYMMDNNYQYSKELLHYCLEREIP 157
Query: 122 VVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAAWEFLE 181
+ SS A + +S + P+N + SK + E++
Sbjct: 158 FLYASSAATYGGRTSDFIESREYE--------------KPLNVFGYSKFLFD----EYVR 199
Query: 182 ENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLSPEDKIPELFGG--- 238
+ ++ V+GP+ + K S + L+ + G
Sbjct: 200 QILPEANSQIVGFRYFNVYGPR----EGHKGSMASVAF-HLNTQLNNGESPKLFEGSENF 254
Query: 239 ---YIDVRDVAKAHLVAFQKRETIGQRLIVSEARFTMQDVLDILNEDFPVLKGNIPVGKP 295
++ V DVA +L + G + + + Q V D + + P
Sbjct: 255 KRDFVYVGDVADVNLWFLE-NGVSGIFNLGTGRAESFQAVADATLAYHKKGQIEY-IPFP 312
Query: 296 GSGATHNTLGATLDNKKSK 314
D +
Sbjct: 313 DKLKGRYQAFTQADLTNLR 331
>1OC2-A nrPDB
Length = 348
Score = 63.4 bits (152), Expect = 2e-10, Method: Composition-based stats.
Identities = 58/339 (17%), Positives = 115/339 (33%), Gaps = 33/339 (9%)
Query: 3 VFVSGANGFIAQHIVDLLLKEDYKVIGSARS----QEKAENLTEAFGNNPKFSMEVVPDI 58
+ V+G GFI + V + V + NL G+ + VV DI
Sbjct: 7 IIVTGGAGFIGSNFVHYVYNNHPDVHVTVLDKLTYAGNKANLEAILGDRVEL---VVGDI 63
Query: 59 SKLDAFDHVFQKHGKDIKIVLHTASPFCFD-ITDSERDLLIPAVNGVKGILHSIKKYAAD 117
+ + D + ++H A+ D + + G +L + +KY
Sbjct: 64 ADAELVDKL----AAKADAIVHYAAESHNDNSLNDPSPFIHTNFIGTYTLLEAARKYDI- 118
Query: 118 SVERVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAAW 177
R S+ V+ + E T E+ + P + Y +K ++
Sbjct: 119 ---RFHHVSTD-EVYGDLPLREDLPGHGEGPGEKFTAETNYN-PSSPYSSTKAASDLIVK 173
Query: 178 EFLEENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLSPEDKI-PELF 236
++ S + T N +GP + ++K + ++ N L + P+ +
Sbjct: 174 AWVR----SFGVKATISNCSNNYGPY---QHIEKFIP--RQITNILAGIKPKLYGEGKNV 224
Query: 237 GGYIDVRDVAKAHLVAFQKRETIGQRLIVSEARFTMQDVLDILNEDFPVLKGNIPVGKPG 296
+I D + K LI ++ ++VL+++ E K
Sbjct: 225 RDWIHTNDHSTGVWAILTKGRMGETYLIGADGEKNNKEVLELILEKMGQPKDAYDHVTDR 284
Query: 297 SGATHNTLGATLDNKKSKKLLG--FKFRNLKETIDDTAS 333
+G L +D K + LG +F + E +++T
Sbjct: 285 AGHD---LRYAIDASKLRDELGWTPQFTDFSEGLEETIQ 320
>2HUN-A nrPDB
Length = 336
Score = 62.2 bits (149), Expect = 3e-10, Method: Composition-based stats.
Identities = 67/353 (18%), Positives = 131/353 (37%), Gaps = 55/353 (15%)
Query: 1 MSVFVSGANGFIAQHIVDLLLKE--DYKVIG--SARSQEKAENLTEAFGNNPKFSMEVVP 56
M + V+G GFI + + +L++ D++VI NL + ++P+++ V
Sbjct: 4 MKLLVTGGMGFIGSNFIRYILEKHPDWEVINIDKLGYGSNPANLKDLE-DDPRYTF-VKG 61
Query: 57 DISKLDAFDHVFQKHGKDIKIVLHTASPFCFDIT-DSERDLLIPAVNGVKGILHSIKKYA 115
D++ + ++ + + V+H A+ D + S L V G +L SI++
Sbjct: 62 DVADY----ELVKELVRKVDGVVHLAAESHVDRSISSPEIFLHSNVIGTYTLLESIRREN 117
Query: 116 ADSVERVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKA 175
+ R V S+ V+ + + E+ + P + Y +K ++
Sbjct: 118 PEV--RFVHVSTD-EVYGDILKGSFT-------------ENDRLMPSSPYSATKAASDML 161
Query: 176 AWEFLEENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLSPEDKIPEL 235
+ + N GP F + + +++ S KIP +
Sbjct: 162 VLGWTRTYNLNASITRCTNNY----GPYQFPEKLIPK---------TIIRASLGLKIP-I 207
Query: 236 FGGYIDVRD--VAKAHLVAFQKRETIGQR---LIVSEARFTMQ-DVLDILNEDFPVLKGN 289
+G +VRD + H+ A + G+ +S +V+ I+ +
Sbjct: 208 YGTGKNVRDWLYVEDHVRAIELVLLKGESREIYNISAGEEKTNLEVVKIILRLMGKGEEL 267
Query: 290 IPVGKPGSGATHNTLGATLDNKKSKKLLGFKFRN---LKETIDDTASQILKFE 339
I + + G L +LD+ K + L K+R E I T LK E
Sbjct: 268 IELVEDRPGHD---LRYSLDSWKITRDL--KWRPKYTFDEGIKKTIDWYLKNE 315
>3SXP-A nrPDB
Length = 362
Score = 58.8 bits (140), Expect = 4e-09, Method: Composition-based stats.
Identities = 40/301 (13%), Positives = 86/301 (28%), Gaps = 45/301 (14%)
Query: 2 SVFVSGANGFIAQHIVDLLLKEDYKVIGSA------------RSQEKAENLTEAFGNNPK 49
++ ++G GF+ ++ + K + G +
Sbjct: 12 TILITGGAGFVGSNLAFHFQENHPKAKVVVLDKFRSNTLFSNNRPSSLGHFKNLIGFKGE 71
Query: 50 FSMEVVPDISKLDAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILH 109
+ DI+ + + H + H A+ + + + ++ +L
Sbjct: 72 V---IAADINNPLDLRRLEKLH---FDYLFHQAAVSDTTMLN-QELVMKTNYQAFLNLLE 124
Query: 110 SIKKYAADSVERVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSK 169
+ A V+ SS V+ K P N Y SK
Sbjct: 125 IARSKKAK----VIYASSAG-VYGNTKA--------------PNVVGKNESPENVYGFSK 165
Query: 170 KFAEKAAWEFLEENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLSPE 229
++ +N + V+GP+ F K+ + L
Sbjct: 166 LCMDEFVLSHSNDNVQ------VGLRYFNVYGPREFYKEKTASMVLQLALGAMAFKEVKL 219
Query: 230 DKIPELFGGYIDVRDVAKAHLVAFQKRETIGQRLIVSEARFTMQDVLDILNEDFPVLKGN 289
+ E ++ + DV +A++ A K + G + + +++ IL E K
Sbjct: 220 FEFGEQLRDFVYIEDVIQANVKAM-KAQKSGVYNVGYSQARSYNEIVSILKEHLGDFKVT 278
Query: 290 I 290
Sbjct: 279 Y 279
>2C54-A nrPDB
Length = 379
Score = 58.4 bits (139), Expect = 5e-09, Method: Composition-based stats.
Identities = 57/339 (16%), Positives = 122/339 (35%), Gaps = 37/339 (10%)
Query: 1 MSVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISK 60
+ + ++GA GFIA HI L E + VI S +K E++TE + +V D+
Sbjct: 30 LKISITGAGGFIASHIARRLKHEGHYVIAS--DWKKNEHMTEDMFCDE---FHLV-DLRV 83
Query: 61 LDAFDHVFQKHGKDIKIVLHTASPF-CFDITDSERDLLIPAVNGVKGILHSIKKYAADSV 119
++ V + + V + A+ S +++ N + I+ + +
Sbjct: 84 MENCLKVTE----GVDHVFNLAADMGGMGFIQSNHSVIMY--NNTMISFNMIEAARINGI 137
Query: 120 ERVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAAWEF 179
+R SS + + +++ E ++ ++P +AY + E E
Sbjct: 138 KRFFYASSACIYPEFKQLETTNVSLKES-------DAWPAEPQDAYGLERLATE----EL 186
Query: 180 LEENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTS---CELVNSLMHLSPEDKIPELF 236
+ E ++GP K ++ + ++ D +
Sbjct: 187 CKHYNKDFGIECRIGRFHNIYGPFGTWKGGREKAPAAFCRKAQTSTDRFEMWGDGLQTRS 246
Query: 237 GGYIDVRDVAKAHLVAFQKRETIGQRLIVSEARFTMQDVLDIL----NEDFPVLKGNIPV 292
+I D ++ K + I S+ +M ++ +++ + P+ P
Sbjct: 247 FTFI---DECVEGVLRLTKSDFREPVNIGSDEMVSMNEMAEMVLSFEEKKLPIHHIPGPE 303
Query: 293 GKPGSGATHNTLGATL---DNKKSKKLLGFKFRNLKETI 328
G G + +N + L N + K+ L + +KE I
Sbjct: 304 GVRGRNSDNNLIKEKLGWAPNMRLKEGLRITYFWIKEQI 342
>3M2P-A nrPDB
Length = 311
Score = 58.0 bits (138), Expect = 6e-09, Method: Composition-based stats.
Identities = 57/323 (17%), Positives = 113/323 (34%), Gaps = 53/323 (16%)
Query: 1 MSVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEV-VPDIS 59
+ + V+G GF+ Q++V+ + + I RS GN E V D +
Sbjct: 3 LKIAVTGGTGFLGQYVVESIKNDGNTPIILTRS----------IGNKAINDYEYRVSDYT 52
Query: 60 KLDAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAADSV 119
D + + D+ V+H A+ S+ + N + + +++
Sbjct: 53 LEDLINQL-----NDVDAVVHLAA-----TRGSQGKISEFHDNEIL-TQNLYDACYENNI 101
Query: 120 ERVVLTSSYAAVFDMAKENDKSLTFNEE--SWNPATWESCQSDPVNAYCGSKKFAEKAAW 177
+V S+ +A +E WN P Y SK E
Sbjct: 102 SNIVYASTISA------------YSDETSLPWNEKELPL----PDLMYGVSKLACEHIGN 145
Query: 178 EFLEENRDSVKFELTAVNPVYVFGPQMFDK-DVKKHLNTSCELVNSLMHLSPEDKIPELF 236
+ + + + +++G + + + + +H + K
Sbjct: 146 IYSRKK----GLCIKNLRFAHLYGFNEKNNYMINRFFRQAFHGEQLTLHANSVAKR---- 197
Query: 237 GGYIDVRDVAKAHLVAFQKRETIGQRLIVSEARFTMQDVLDILNEDFPVLKGNIPVGKPG 296
++ +D AK+ + A ++ + G I S T +V + +N F K N+ V P
Sbjct: 198 -EFLYAKDAAKSVIYALKQEKVSGTFNIGSGDALTNYEVANTINNAF-GNKDNLLVKNP- 254
Query: 297 SGATHNTLGATLDNKKSKKLLGF 319
A + +D+ K+K+LL F
Sbjct: 255 -NANEGIHSSYMDSSKAKELLDF 276
>6BI4-A nrPDB
Length = 346
Score = 57.6 bits (137), Expect = 7e-09, Method: Composition-based stats.
Identities = 48/249 (19%), Positives = 102/249 (40%), Gaps = 39/249 (15%)
Query: 1 MSVFVSGANGFIAQHIVDLLLK--EDYKVIGSARSQEKAENL--TEAFGNNPKFSMEVVP 56
M++ V+G GFI + V +L+ E YK+I + + + NL ++ ++P + V
Sbjct: 25 MNILVTGGAGFIGSNFVHYMLQSYETYKII-NFDALTYSGNLNNVKSIQDHPNY-YFVKG 82
Query: 57 DISKLDAFDHVFQKHGKDIKIVLHTASPFCFDIT-DSERDLLIPAVNGVKGILHSIKKYA 115
+I + +HV ++ +D++++++ A+ D + ++ V G +L +KKY
Sbjct: 83 EIQNGELLEHVIKE--RDVQVIVNFAAESHVDRSIENPIPFYDTNVIGTVTLLELVKKYP 140
Query: 116 ADSVERVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKA 175
+ +V S V+ E P + Y SK A+
Sbjct: 141 HIKLVQV----STDEVY--GSLGKTGRFTEETP----------LAPNSPYSSSKASADMI 184
Query: 176 AWEFLEENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLSPEDKIPEL 235
A + + + + + +GP + + +L+ ++ + E K L
Sbjct: 185 ALAYYK----TYQLPVIVTRCSNNYGPYQYPE----------KLIPLMVTNALEGKKLPL 230
Query: 236 FGGYIDVRD 244
+G ++VRD
Sbjct: 231 YGDGLNVRD 239
>1RKX-A nrPDB
Length = 357
Score = 56.8 bits (135), Expect = 1e-08, Method: Composition-based stats.
Identities = 47/270 (17%), Positives = 80/270 (29%), Gaps = 32/270 (11%)
Query: 2 SVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKL 61
VFV+G GF + L V G + + +L E + DI
Sbjct: 11 RVFVTGHTGFKGGWLSLWLQTMGATVKGYSLTAPTVPSLFET-ARVADGMQSEIGDIRDQ 69
Query: 62 DAFDHVFQKHGKDIKIVLHTAS-PFCFDITDSERDLLIPAVNGVKGILHSIKKYAADSVE 120
+ ++ +I V H A+ P + V G +L +I+ V+
Sbjct: 70 NKLLESIREFQPEI--VFHMAAQPLVRLSYSEPVETYSTNVMGTVYLLEAIRHVGG--VK 125
Query: 121 RVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAAWEFL 180
VV +S ++ + W E+ + Y SK AE +
Sbjct: 126 AVVNITS-------------DKCYDNKEWIWGYRENEAMGGYDPYSNSKGCAELVTSSYR 172
Query: 181 E-----ENRDSVKFELTAVNPVYVF--GPQMFDKDVKKHLNTSCELVNSLMHLSPEDKIP 233
N + V V G D+ V L + ++ + P
Sbjct: 173 NSFFNPANYGQHGTAVATVRAGNVIGGGDWALDRIVPDILRAFEQSQPVII------RNP 226
Query: 234 ELFGGYIDVRDVAKAHLVAFQKRETIGQRL 263
+ V + +L+ QK T G
Sbjct: 227 HAIRPWQHVLEPLSGYLLLAQKLYTDGAEY 256
>1DB3-A nrPDB
Length = 372
Score = 55.3 bits (131), Expect = 4e-08, Method: Composition-based stats.
Identities = 41/253 (16%), Positives = 93/253 (36%), Gaps = 36/253 (14%)
Query: 4 FVSGANGFIAQHIVDLLLKEDYKVIGSAR-----SQEKAENL-TEAFGNNPKFSMEVVPD 57
++G G ++ + LL++ Y+V G R + E+ +++ + NPKF + D
Sbjct: 5 LITGVTGQDGSYLAEFLLEKGYEVHGIKRRASSFNTERVDHIYQDPHTCNPKFHLHY-GD 63
Query: 58 ISKLDAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAAD 117
+S + ++ D L S E + A+ G +L +I+ +
Sbjct: 64 LSDTSNLTRILREVQPDEVYNLGAMSHVAVSFESPEYTADVDAM-GTLRLLEAIRFLGLE 122
Query: 118 SVERVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAAW 177
R +S + ++ + +E + E+ P + Y +K +A W
Sbjct: 123 KKTRF-YQASTSELYGLVQEIPQK-------------ETTPFYPRSPYAVAKLYA---YW 165
Query: 178 EFLEENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNT--SCELVNSLMHLSPEDKIPEL 235
+ R+S Y +F+ + + T + ++ ++ +++ +
Sbjct: 166 ITVNY-RESYGM--------YACNGILFNHESPRRGETFVTRKITRAIANIAQGLESCLY 216
Query: 236 FGGYIDVRDVAKA 248
G +RD A
Sbjct: 217 LGNMDSLRDWGHA 229
>1ORR-A nrPDB
Length = 347
Score = 54.1 bits (128), Expect = 8e-08, Method: Composition-based stats.
Identities = 35/267 (13%), Positives = 81/267 (30%), Gaps = 17/267 (6%)
Query: 3 VFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAE-NLTEAFGNNPKFSMEVVPDISKL 61
+ ++G GF+ ++ L + +I K + + F V DI
Sbjct: 4 LLITGGCGFLGSNLASFALSQGIDLIVFDNLSRKGATDNLHWLSSLGNFEF-VHGDIRNK 62
Query: 62 DAFDHVFQKHGKDIKIVLHTASPFCFDIT-DSERDLLIPAVNGVKGILHSIKKYAADSVE 120
+ + K+ H A + D+ V G +L ++++Y ++
Sbjct: 63 NDVTRLITKYMP--DSCFHLAGQVAMTTSIDNPCMDFEINVGGTLNLLEAVRQYNSNC-- 118
Query: 121 RVVLTSSYAAVFDMAKENDKSLTFNEESWNPATW--ESCQSDPVNAYCGSKKFAEKAAWE 178
++ +S+ D+ + + ES Q D + Y SK A++ +
Sbjct: 119 NIIYSSTNKVYGDLEQYKYNETETRYTCVDKPNGYDESTQLDFHSPYGCSKGAADQYMLD 178
Query: 179 FLEENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLSPEDKIPELFGG 238
+ ++G + F + + C+ + + + G
Sbjct: 179 YAR----IFGLNTVVFRHSSMYGGRQFATYDQGWVGWFCQKAVEIKNGINKPFTISGNGK 234
Query: 239 YI----DVRDVAKAHLVAFQKRETIGQ 261
+ D+ + A I
Sbjct: 235 QVRDVLHAEDMISLYFTALANVSKIRG 261
>2PZM-A nrPDB
Length = 330
Score = 53.4 bits (126), Expect = 2e-07, Method: Composition-based stats.
Identities = 26/213 (12%), Positives = 73/213 (34%), Gaps = 33/213 (15%)
Query: 1 MSVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISK 60
M + ++G G + ++++ L + ++++ + + E S+ + ++
Sbjct: 21 MRILITGGAGCLGSNLIEHWLPQGHEILV-IDNFATGK--REVLPPVAGLSV-IEGSVTD 76
Query: 61 LDAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAADSVE 120
+ F V+H+A+ + D A V+G ++ K + V+
Sbjct: 77 AGLLERAFDSFKP--THVVHSAAAYK-----DPDDWAEDAATNVQGSINVAKAASKAGVK 129
Query: 121 RVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAAWEFL 180
R++ ++ + + + + P +Y SK E A+ +
Sbjct: 130 RLL---NFQTALCYGRPATVPIPID-----------SPTAPFTSYGISKTAGE--AFLMM 173
Query: 181 EENRDSVKFELTAVNPVYVFGPQMFDKDVKKHL 213
+ + ++ V GP++ +
Sbjct: 174 SD------VPVVSLRLANVTGPRLAIGPIPTFY 200
>4G5H-A nrPDB
Length = 363
Score = 53.0 bits (125), Expect = 2e-07, Method: Composition-based stats.
Identities = 41/265 (15%), Positives = 90/265 (33%), Gaps = 22/265 (8%)
Query: 3 VFVSGANGFIAQHIVDLLLKEDYK-VIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKL 61
+ ++G G ++ L + K + +R ++K +++ + + NN K + D+
Sbjct: 28 LLITGGTGSFGNAVMKRFLDSNIKEIRIFSRDEKKQDDIRKKY-NNSKLKFYI-GDVRDS 85
Query: 62 DAFDHVFQKHGKDIKIVLHTASPFCFDITD-SERDLLIPAVNGVKGILHSIKKYAADSVE 120
+ + +D+ V H A+ + + + + G + +L S +V+
Sbjct: 86 QS----VETAMRDVDYVFHAAALKQVPSCEFFPVEAVKTNIIGTENVLQSAIH---QNVK 138
Query: 121 RVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAAWEFL 180
+V+ S+ A + + + + + + A + + L
Sbjct: 139 KVICLSTDKAAYPINAMGISKAMMEKVFVAKSRNIRSEQTLICGTRYGNVMASRGSVIPL 198
Query: 181 EENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLSPEDKIPELFGGYI 240
++ LT +P + L + ELV + I
Sbjct: 199 FIDKIKAGEPLTITDPDMT--RFLMS------LEDAVELVVHAFKHAETGDIMVQKAPSS 250
Query: 241 DVRDVAKAHLVAFQKR---ETIGQR 262
V D+A A L F+ E IG R
Sbjct: 251 TVGDLATALLELFEADNAIEIIGTR 275
>2GN9-A nrPDB
Length = 344
Score = 53.0 bits (125), Expect = 2e-07, Method: Composition-based stats.
Identities = 34/207 (16%), Positives = 77/207 (37%), Gaps = 45/207 (21%)
Query: 2 SVFVSGANGFIAQHIVDLLLK--EDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDIS 59
++ ++G G + V +L K+I +R + K + N+P+ + D+
Sbjct: 23 TILITGGTGSFGKCFVRKVLDTTNAKKIIVYSRDELKQSEM-AMEFNDPRMRF-FIGDVR 80
Query: 60 KLDAFDHVFQKHGKDIKIVLHTASPFCFDITD-SERDLLIPAVNGVKGILHSIKKYAADS 118
L+ ++ + + I +H A+ I + + + + + G ++++ K A
Sbjct: 81 DLERLNYALE----GVDICIHAAALKHVPIAEYNPLECIKTNIMGASNVINACLKNAISQ 136
Query: 119 VERVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAAWE 178
V + L++ AA +P+N Y +K ++K
Sbjct: 137 V--IALSTDKAA-----------------------------NPINLYGATKLCSDKL--- 162
Query: 179 FLEENR--DSVKFELTAVNPVYVFGPQ 203
F+ N S + + + V V G +
Sbjct: 163 FVSANNFKGSSQTQFSVVRYGNVVGSR 189
>4BKP-A nrPDB
Length = 336
Score = 52.6 bits (124), Expect = 3e-07, Method: Composition-based stats.
Identities = 54/339 (15%), Positives = 103/339 (30%), Gaps = 46/339 (13%)
Query: 1 MSVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISK 60
M + V+G +G + + I Q+ + G + F D++
Sbjct: 23 MRILVTGGSGLVGKAI-----------------QKVVADGAGLPGEDWVFVSSKDADLTD 65
Query: 61 LDAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLL--IPAVNGVKGILHSIKKYAADS 118
+F+K V+H A+ + + +L V+ +LHS + A
Sbjct: 66 TAQTRALFEKVQP--THVIHLAAMVGGLFRNIKYNLDFWRKNVHMNDNVLHSAFEVGARK 123
Query: 119 VERVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAAWE 178
V S + K +E + Y +K+ +
Sbjct: 124 V-----VSCLSTCIFPDKTTYP---IDET----MIHNGPPHNSNFGYSYAKRMIDVQNRA 171
Query: 179 FLEENRDSVKFELTAVNPVYVFGPQ----MFDKDVKKHLNTSCELVNSLMHLSPEDKIPE 234
+ ++ TAV P VFGP + D V L L S
Sbjct: 172 YFQQ----YGCTFTAVIPTNVFGPHDNFNIEDGHVLPGLIHKVHLAKSSGSALTVWGTGN 227
Query: 235 LFGGYIDVRDVAKAHLVAF-QKRETIGQRL-IVSEARFTMQDVLDILNEDFPVLKGNIPV 292
+I D+A+ + + E L + E ++++ + + E G +
Sbjct: 228 PRRQFIYSLDLAQLFIWVLREYNEVEPIILSVGEEDEVSIKEAAEAVVEAM-DFHGEVTF 286
Query: 293 GKPGSGATHNTLGATLDNKKSKKLLGFKFRNLKETIDDT 331
S ++K L F+F K+ + +T
Sbjct: 287 DTTKSDG--QFKKTASNSKLRTYLPDFRFTPFKQAVKET 323
>3RUE-A nrPDB
Length = 351
Score = 52.2 bits (123), Expect = 3e-07, Method: Composition-based stats.
Identities = 46/302 (15%), Positives = 97/302 (32%), Gaps = 42/302 (13%)
Query: 4 FVSGANGFIAQHIVDLLLKEDYKVIGSAR-------SQEKAENLTEAFGNNPKFSMEVVP 56
++G GFI ++++ LLK + VIG + ++ + L +F +
Sbjct: 29 LITGVAGFIGSNLLEKLLKLNQVVIGLDNFSTGHQYNLDEVKTLVSTE-QWSRFCF-IEG 86
Query: 57 DISKLDAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGI---LHSIKK 113
DI L + V K + VLH A+ + R ++ P I L+ +
Sbjct: 87 DIRDLTTCEQVM----KGVDHVLHQAA-----LGSVPRSIVDPITTNATNITGFLNILHA 137
Query: 114 YAADSVERVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAE 173
V+ +S + + +L EE+ +P++ Y +K E
Sbjct: 138 AKNAQVQSFTYAASSST-----YGDHPALPKVEENIG---------NPLSPYAVTKYVNE 183
Query: 174 KAAWEFLEENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLSPEDKIP 233
A + + F+ + VFG + + +
Sbjct: 184 IYAQVYAR----TYGFKTIGLRYFNVFGRRQDPNGAYAAVIPKWTAAMLKGDDVYINGDG 239
Query: 234 ELFGGYIDVRDVAKAHLV-AFQKRETIGQRLIVSEARFTMQDVLDILNEDFPVLKGNIPV 292
E + + +V + +++ A K V+ + ++ + L +
Sbjct: 240 ETSRDFCYIDNVIQMNILSALAKDSAKDNIYNVAVG--DRTTLNELSGYIYDELNLIHHI 297
Query: 293 GK 294
K
Sbjct: 298 DK 299
>5UZH-A nrPDB
Length = 345
Score = 51.1 bits (120), Expect = 8e-07, Method: Composition-based stats.
Identities = 35/267 (13%), Positives = 91/267 (34%), Gaps = 40/267 (14%)
Query: 4 FVSGANGFIAQHIVDLLLKEDYKVIGSAR-----SQEKAENL-TEAFGNNPKFSMEVVPD 57
++G G ++ + LL++ Y V G R + + E+L + KF + + D
Sbjct: 5 LITGITGQDGSYLAEFLLEKGYMVYGIIRRSSSFNTGRVEHLYKDIHITKAKFKL-LYGD 63
Query: 58 ISKLDAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVN----GVKGILHSIKK 113
++ + K + + A+ ++ ++ N G +L +I+
Sbjct: 64 LTDTGNLISIIAKIKP--DEIYNLAAQSHVKVS---FEMPEYTANVDGIGTLRLLEAIRA 118
Query: 114 YAADSVERVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAE 173
+ + +S + ++ + +E + E+ P + Y +K +
Sbjct: 119 CGLEKKTKF-YQASTSELYGLVQEVPQK-------------ETTPFYPRSPYACAKLY-- 162
Query: 174 KAAWEFLEENRDSVKFELTAVNPVYVF---GPQMFDKDVKKHLNTSCELVNSLMHLSPED 230
+ W + F L + + GP + + + + ++L D
Sbjct: 163 -SYWIVVNYREAYNMFALNGILFNHESIRRGPTFVTRKITMAVARIKLGLQDCLYLGNLD 221
Query: 231 KIPELFGGYIDVRDVAKAHLVAFQKRE 257
+ + +D +A + Q+ +
Sbjct: 222 AERD----WGHAKDYVEAMWLMLQQEQ 244
>6AQY-A nrPDB
Length = 341
Score = 49.9 bits (117), Expect = 2e-06, Method: Composition-based stats.
Identities = 55/349 (15%), Positives = 101/349 (28%), Gaps = 55/349 (15%)
Query: 3 VFVSGANGFIA---QHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDIS 59
+ V+G G +HIV E F D+
Sbjct: 27 ILVTGGTGLFGKAVEHIVK----------------------KEQIKGKWVFLGSKDGDLR 64
Query: 60 KLDAFDHVFQKHGKDIKIVLHTASPFC--FDITDSERDLLIPAVNGVKGILHSIKKYAAD 117
DA F+K+ V+H A+ F + + + VN IL +
Sbjct: 65 DADACKQPFEKYRP--TYVIHLAAFVGGLFKNMNFKVSFWLDNVNMNNNILTCCYDFGVK 122
Query: 118 SVERVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAE-KAA 176
+ + + + EE + E NAY +K+ +
Sbjct: 123 K--------TISCLSTCVFPDKIEYPITEEKLH----EGPPHFSNNAYAYAKRMLDMLGR 170
Query: 177 WEFLEENRDSVKFELTAVNPVYVFGPQ-MFDKDVKKHLNTSCELV-----NSLMHLSPED 230
W + + T+V P +FGP F+ + L N +
Sbjct: 171 WYNEKAVNEGKSCLFTSVIPTNLFGPHDNFNVEAGHVLPGLMHKCYKAQQNGTDFVVFGS 230
Query: 231 KIPELFGGYIDVRDVAKAHLVAFQKRETIGQRLIV--SEARFTMQDVLDILNEDFPVLKG 288
P Y D A+ L ++ ++ E ++ V + + F G
Sbjct: 231 GKPLRQFLYSH--DAARMLLWTMFNYQSEEPIMLCVSEEDEKSIGQVAQTIKDAF-NFTG 287
Query: 289 NIPVGKPGSGATHNTLGATLDNKKSKKLLGFKFRNLKETIDDTASQILK 337
N+ S A + + K + F++ ++ I +T L+
Sbjct: 288 NMVFDT--SKADGQYKKTSSNAKFLRLNPTFQYTPFEQAIKETVQWFLE 334
>5U9C-A nrPDB
Length = 292
Score = 49.5 bits (116), Expect = 2e-06, Method: Composition-based stats.
Identities = 57/325 (17%), Positives = 100/325 (30%), Gaps = 65/325 (20%)
Query: 3 VFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKLD 62
+ ++G G + ++ L DY VI + R+ ++S +
Sbjct: 8 ILITGGTGMLGAYVTSALKDTDYNVIVTERN---------------------TLNLSVPE 46
Query: 63 AFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHS-IKKYAADSVER 121
A ++LH A+ D+ + E PA G+ L + AA
Sbjct: 47 AIFSYITAEKP--DVILHFAAETDVDLCERE-----PARAGIYNHLATEQIAQAAKFCGA 99
Query: 122 VVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAAWEFLE 181
+L S + VF + L++NE P+N Y SK E +
Sbjct: 100 WLLYLSSSNVFG----GEGKLSYNELDIPL---------PMNYYGRSKLIGESSV----- 141
Query: 182 ENRDSVKFELTAVNPVYVF--GPQMFDKDVKKHLNTSCELVNSLMHLSPEDKIPELFGGY 239
R++ + ++ GP K V K + S+ +S G
Sbjct: 142 --RNACTNNHLIIRAGWMIGGGPDKDHKFVGKIIQQIKAGSTSIKAVSDR------LGSI 193
Query: 240 IDVRDVAKAHLVAFQKRETIGQRLIVSEAR------FTMQDVLDILNEDFPVLKGNIP-- 291
+ + A KR T S + D+L+ + PV P
Sbjct: 194 TSAMQLCNFIIWAINKRHTGTLHFASSGTISRFDIACAIGDLLNFKGDIIPVHSSVFPLS 253
Query: 292 VGKPGSGATHNTLGATLDNKKSKKL 316
+P S + + L + L
Sbjct: 254 APRPYSEGIESIYMSILSDAPKPSL 278
>4J2O-A nrPDB
Length = 363
Score = 48.7 bits (114), Expect = 4e-06, Method: Composition-based stats.
Identities = 22/136 (16%), Positives = 57/136 (41%), Gaps = 13/136 (9%)
Query: 3 VFVSGANGFIAQHIVDLLLKEDYK-VIGSARSQEKAENLTEAF-GNNPKFSMEVVPDISK 60
+ ++G G ++ L+ D K + +R ++K +++ + + KF + D+
Sbjct: 26 LLITGGTGSFGNAVLKRFLETDIKEIRIFSRDEKKQDDMRKKYHSAKLKF---YIGDVRD 82
Query: 61 LDAFDHVFQKHGKDIKIVLHTASPFCFDITDS-ERDLLIPAVNGVKGILHSIKKYAADSV 119
++ + + + H A+ + + + V G + +L + + + V
Sbjct: 83 YNS----ILNATRGVDYIYHAAALKQVPSCEFHPMEAVKTNVLGTENVLEAAIQ---NHV 135
Query: 120 ERVVLTSSYAAVFDMA 135
+RVV S+ AV+ +
Sbjct: 136 KRVVCLSTDKAVYPIN 151
>3WMX-A nrPDB
Length = 358
Score = 48.4 bits (113), Expect = 4e-06, Method: Composition-based stats.
Identities = 40/302 (13%), Positives = 88/302 (29%), Gaps = 55/302 (18%)
Query: 3 VFVSGANGFIAQHIVDLLLKE-DYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKL 61
+ + GANG I + L + + ++ ++ + + +
Sbjct: 28 ILIVGANGQIGSELALALAERYGRTNVITSDVVPTGRHV---------HLTHEMLNATDR 78
Query: 62 DAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAADSVER 121
V ++HG I V A+ E+ + +L+ ++ +ER
Sbjct: 79 GELATVVERHG--ITQVYLLAAAL---SATGEKAPQWAWNLNMTSLLNVLELARQTGLER 133
Query: 122 VVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAAWEFLE 181
V SS AA F ++ + +P Y SK+ E W
Sbjct: 134 VFWPSSIAA-FGPTTPAGQTP------------QKTVMEPTTVYGISKQAGE--GW--CR 176
Query: 182 ENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELV----------NSLMHLSPEDK 231
+ ++ +V P + T+ V L ++
Sbjct: 177 WYHANHGVDVRSVRY-----PGLISHKTPPGGGTTDYAVDIFHAAVTGEPYTCFLKEDEA 231
Query: 232 IPELFGGYIDVRDVAKAHLVAFQKRE---TIGQRLIVSEARFTMQDVLDILNEDFPVLKG 288
+P ++ + D +A + + + ++ FT + + E P +
Sbjct: 232 LPMMY-----MPDAIRATIELMEAPADKLSERGSYNIAGMSFTPAQIAAAIREQVPGFQI 286
Query: 289 NI 290
Sbjct: 287 RY 288
>1RPN-A nrPDB
Length = 335
Score = 47.6 bits (111), Expect = 8e-06, Method: Composition-based stats.
Identities = 36/221 (16%), Positives = 72/221 (32%), Gaps = 25/221 (11%)
Query: 2 SVFVSGANGFIAQHIVDLLLKEDYKVIGSA--RSQEKAENLTEAFGNNPKFSMEVVPDIS 59
S V+G G ++ LLL++ Y+V G RS + L E G E D++
Sbjct: 16 SALVTGITGQDGAYLAKLLLEKGYRVHGLVARRSSDTRWRLREL-GIEGDIQYE-DGDMA 73
Query: 60 KLDAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAADSV 119
+ K V + A+ + + V G+ H ++ S
Sbjct: 74 DACSVQRAVIKAQPQ--EVYNLAAQSFVGAS--WNQPVTTGVVDGLGVTHLLEAIRQFSP 129
Query: 120 ERVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAAWEF 179
E +S + +F + + + E+ P + Y +K + W
Sbjct: 130 ETRFYQASTSEMFGLIQAERQD-------------ENTPFYPRSPYGVAKLYGH---WIT 173
Query: 180 LEENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELV 220
+ R+S ++ P + V + + + +
Sbjct: 174 VNY-RESFGLHASSGILFNHESPLRGIEFVTRKVTDAVARI 213
>2Z95-A nrPDB
Length = 345
Score = 47.2 bits (110), Expect = 1e-05, Method: Composition-based stats.
Identities = 25/170 (14%), Positives = 59/170 (34%), Gaps = 17/170 (10%)
Query: 2 SVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKL 61
++G G ++ LLL++ Y+V G+ R + + + D+ +
Sbjct: 5 RALITGIRGQDGAYLAKLLLEKGYEVYGADRRSGEFASWRLKELGIENDVKIIHMDLLEF 64
Query: 62 DAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAADSVER 121
+K V + A+ ++ E+ +L V+ G+L ++ +
Sbjct: 65 SNIIRTIEKVQP--DEVYNLAAQSFVGVS-FEQPILTAEVD-AIGVLRILEALRTVKPDT 120
Query: 122 VVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKF 171
+S + +F + + E++ P + Y +K F
Sbjct: 121 KFYQASTSEMFG----KVQEIPQTEKT---------PFYPRSPYAVAKLF 157
>1N7G-A nrPDB
Length = 381
Score = 47.2 bits (110), Expect = 1e-05, Method: Composition-based stats.
Identities = 23/176 (13%), Positives = 53/176 (30%), Gaps = 12/176 (6%)
Query: 4 FVSGANGFIAQHIVDLLLKEDYKVIGSARSQEK-AENLTEAFGNNPK-----FSMEVVPD 57
++G G ++ + LL + Y+V G R +P D
Sbjct: 32 LITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKLHYAD 91
Query: 58 ISKLDAFDHVFQKHGKDIKIVLHTASPFCFDIT-DSERDLLIPAVNGVKGILHSIKKYAA 116
++ + V + A+ ++ + G +L +++ +
Sbjct: 92 LTDASSLRRWIDVIKP--DEVYNLAAQSHVAVSFEIPDYTADVVATGALRLLEAVRSHTI 149
Query: 117 DSVERVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFA 172
DS V + ++ + +S T +P C + Y + + A
Sbjct: 150 DSGRTVKYYQAGSSEMFGSTPPPQSETTPFHPRSPYAASKCAAH---WYTVNYREA 202
>6GCS-E nrPDB
Length = 375
Score = 46.8 bits (109), Expect = 1e-05, Method: Composition-based stats.
Identities = 31/176 (17%), Positives = 61/176 (34%), Gaps = 13/176 (7%)
Query: 2 SVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKL 61
+ V GANGF+ ++ L K V+ R +E A+ + G+ + + D+ L
Sbjct: 55 TATVFGANGFLGSYLTAKLAKHGTTVVVPYR-EEMAKRHLKVTGDLGVVNFLEM-DLRNL 112
Query: 62 DAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAADSVER 121
++ D V H+ + E V+G + ++ R
Sbjct: 113 ESIDEA----------VRHSDIVVNLIGREYETKNFNYYDVHVEGARRIAEAVKKHNIAR 162
Query: 122 VVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYC-GSKKFAEKAA 176
+ S++ A D E + + E+ + P + K F ++ A
Sbjct: 163 YIHVSAFNAEIDSPSEFNHTKGLGEQVTKDIVPWATIVRPAPMFGREDKWFLDRMA 218
>6GPK-A nrPDB
Length = 373
Score = 45.7 bits (106), Expect = 3e-05, Method: Composition-based stats.
Identities = 34/263 (12%), Positives = 81/263 (30%), Gaps = 27/263 (10%)
Query: 4 FVSGANGFIAQHIVDLLLKEDYKVIGSA-RSQEKAENLTEAFGNNPKFSMEVV-----PD 57
++G G ++ + LL++ Y+V G RS E NP+ +E D
Sbjct: 28 LITGITGQDGSYLAEFLLEKGYEVHGIVRRSSSFNTGRIEHLYKNPQAHIEGNMKLHYGD 87
Query: 58 ISKLDAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVN-GVKGILHSIKKYAA 116
++ + + + + + I+ + G +L ++K
Sbjct: 88 LTDSTCLVKIINEVKP--TEIYNLGAQSHVKISFDLAEYTADVDGVGTLRLLDAVKTCGL 145
Query: 117 DSVERVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAA 176
+ + +S + ++ +E + E+ P + Y +K +A
Sbjct: 146 INSVKF-YQASTSQLYGKVQEIPQK-------------ETTPFYPRSPYGAAKLYA---Y 188
Query: 177 WEFLEENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLSPEDKIPELF 236
W + F + + P+ V + ++ S + +
Sbjct: 189 WIVVNFREAYNLFAVNGIL-FNHESPRRGANFVTRKISRSVAKIYLGQLECFSLGNLDAK 247
Query: 237 GGYIDVRDVAKAHLVAFQKRETI 259
+ +D +A + Q E
Sbjct: 248 RDWGHAKDYVEAMWLMLQNDEPE 270
>5OVL-A nrPDB
Length = 300
Score = 44.9 bits (104), Expect = 6e-05, Method: Composition-based stats.
Identities = 22/145 (15%), Positives = 48/145 (33%), Gaps = 20/145 (13%)
Query: 2 SVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKL 61
SV V+G N I I L + +KV + R ++L V D++
Sbjct: 70 SVLVTGGNRGIGLAIARRLAADGHKVAVTHRGSGAPDDL-----------FGVQCDVTDS 118
Query: 62 DAFDHVF---QKHGKDIKIVLHTAS------PFCFDITDSERDLLIPAVNGVKGILHSIK 112
A D F ++H +++++ A E + + + +
Sbjct: 119 AAVDRAFKEVEEHQGPVEVLVANAGISKDAFLMRMTEERFEEVINTNLTGAFRCAQRASR 178
Query: 113 KYAADSVERVVLTSSYAAVFDMAKE 137
R++ S + ++ + +
Sbjct: 179 TMQRKRFGRIIFIGSVSGMWGIGNQ 203
>5OVJ-A nrPDB
Length = 256
Score = 44.9 bits (104), Expect = 6e-05, Method: Composition-based stats.
Identities = 22/145 (15%), Positives = 48/145 (33%), Gaps = 20/145 (13%)
Query: 2 SVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKL 61
SV V+G N I I L + +KV + R ++L V D++
Sbjct: 26 SVLVTGGNRGIGLAIARRLAADGHKVAVTHRGSGAPDDL-----------FGVQCDVTDS 74
Query: 62 DAFDHVF---QKHGKDIKIVLHTAS------PFCFDITDSERDLLIPAVNGVKGILHSIK 112
A D F ++H +++++ A E + + + +
Sbjct: 75 AAVDRAFKEVEEHQGPVEVLVANAGISKDAFLMRMTEERFEEVINTNLTGAFRCAQRASR 134
Query: 113 KYAADSVERVVLTSSYAAVFDMAKE 137
R++ S + ++ + +
Sbjct: 135 TMQRKRFGRIIFIGSVSGMWGIGNQ 159
>3SLK-A nrPDB
Length = 795
Score = 43.7 bits (101), Expect = 1e-04, Method: Composition-based stats.
Identities = 29/147 (19%), Positives = 51/147 (34%), Gaps = 19/147 (12%)
Query: 2 SVFVSGANGFIAQHIVDLL-LKEDYK--VIGSARSQEK--AENLTEAFGNNPKFSMEVVP 56
+V V+G G + + L ++ + V+ S R A L
Sbjct: 532 TVLVTGGTGALGAEVARHLVIERGVRNLVLVSRRGPAASGAAELVAQLTAYGAEVSLQAC 591
Query: 57 DISKLDAFDHVFQKHGKD---IKIVLHTASPFCFDITDS-----ERDLLIPAVNGVKGIL 108
D++ + V D + V+H A +++S +L P V+G + +L
Sbjct: 592 DVADRETLAKVL-ASIPDEHPLTAVVHAAGVLDDGVSESLTVERLDQVLRPKVDGARNLL 650
Query: 109 HSIKKYAADSVERVVLTSSYAAVFDMA 135
I A +VL SS + V
Sbjct: 651 ELIDPDVA-----LVLFSSVSGVLGSG 672
>1UZM-A nrPDB
Length = 247
Score = 43.0 bits (99), Expect = 2e-04, Method: Composition-based stats.
Identities = 23/145 (15%), Positives = 51/145 (35%), Gaps = 20/145 (13%)
Query: 2 SVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKL 61
SV V+G N I I L + +KV + R + L V D++
Sbjct: 17 SVLVTGGNRGIGLAIAQRLAADGHKVAVTHRGSGAPKGL-----------FGVEVDVTDS 65
Query: 62 DAFDHVF---QKHGKDIKIVLHTASPFCFD-----ITDSERDLLIPAVNGVKGILHSI-K 112
DA D F ++H +++++ A + ++ + G + +
Sbjct: 66 DAVDRAFTAVEEHQGPVEVLVSNAGLSADAFLMRMTEEKFEKVINANLTGAFRVAQRASR 125
Query: 113 KYAADSVERVVLTSSYAAVFDMAKE 137
+ R++ S + ++ + +
Sbjct: 126 SMQRNKFGRMIFIGSVSGLWGIGNQ 150
>3RFT-A nrPDB
Length = 267
Score = 42.2 bits (97), Expect = 4e-04, Method: Composition-based stats.
Identities = 24/181 (13%), Positives = 54/181 (29%), Gaps = 32/181 (17%)
Query: 2 SVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKL 61
+ V+GA G + + + + L + +L+ P V D++
Sbjct: 5 RLLVTGAAGQLGRVMRERL--------APMAEILRLADLSPLDPAGPN-EECVQCDLADA 55
Query: 62 DAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAADSVER 121
+A + + ++H + +L + G+ + + + + R
Sbjct: 56 NAVNAMV----AGCDGIVHLGG---ISVEKPFEQILQGNIIGLYNLYEAARAHGQP---R 105
Query: 122 VVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAAWEFLE 181
+V SS + + P Y SK F E A + +
Sbjct: 106 IVFASSNHTIGYYPQTERLGPDVPAR-------------PDGLYGVSKCFGENLARMYFD 152
Query: 182 E 182
+
Sbjct: 153 K 153
>4WPG-A nrPDB
Length = 289
Score = 42.2 bits (97), Expect = 4e-04, Method: Composition-based stats.
Identities = 37/181 (20%), Positives = 61/181 (33%), Gaps = 41/181 (22%)
Query: 3 VFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKLD 62
+ ++G+NG + + LL + + E DI+ D
Sbjct: 7 ILITGSNGQLGTELRYLLDERGVD-YVAVDVAE--------------------MDITNED 45
Query: 63 AFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVN--GVKGILHSIKKYAADSVE 120
+ VF + +V H A+ D + E L A+N G + I + KY A
Sbjct: 46 KVEAVFAQVKP--TLVYHCAAYTAVDAAEDEGKALNEAINVTGSENIAKACGKYGAT--- 100
Query: 121 RVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAAWEFL 180
+V S+ VFD K + + DP Y +K+ E A +
Sbjct: 101 -LVYISTD-YVFDGNKPVGQEWVETDHP-----------DPKTEYGRTKRLGELAVERYA 147
Query: 181 E 181
E
Sbjct: 148 E 148
>1BDB-A nrPDB
Length = 277
Score = 41.8 bits (96), Expect = 4e-04, Method: Composition-based stats.
Identities = 26/147 (17%), Positives = 50/147 (34%), Gaps = 16/147 (10%)
Query: 2 SVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKL 61
+V ++G + + +VD + E KV +S E L E ++ + +V D+ L
Sbjct: 7 AVLITGGASGLGRALVDRFVAEGAKVAVLDKSAE---RLAELETDHGDNVLGIVGDVRSL 63
Query: 62 DAFDHVFQKHG---KDIKIVLHTASPFCFDIT--DSERDLLIPA--------VNGVKGIL 108
+ + I ++ A + + D + L A V G +
Sbjct: 64 EDQKQAASRCVARFGKIDTLIPNAGIWDYSTALVDLPEESLDAAFDEVFHINVKGYIHAV 123
Query: 109 HSIKKYAADSVERVVLTSSYAAVFDMA 135
+ S V+ T S A +
Sbjct: 124 KACLPALVASRGNVIFTISNAGFYPNG 150
>4B4O-A nrPDB
Length = 298
Score = 41.0 bits (94), Expect = 8e-04, Method: Composition-based stats.
Identities = 34/284 (11%), Positives = 73/284 (25%), Gaps = 57/284 (20%)
Query: 1 MSVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISK 60
M V V G GFI + LL ++V +R
Sbjct: 1 MRVLVGGGTGFIGTALTQLLNARGHEVTLVSRKPGPGR---------------------- 38
Query: 61 LDAFDHVFQKHGKDIKIVLHTA-----SPFCFDITDSERDLLIPAVNGVKGILHSIKKYA 115
+D + ++ A +P ++++L + + + +I K
Sbjct: 39 -ITWDELAASGLPSCDAAVNLAGENILNPLRRWNETFQKEVLGSRLETTQLLAKAITKAP 97
Query: 116 ADSVERVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKA 175
V++T + + ++E+S ++ + ++
Sbjct: 98 QPPKAWVLVT---GVAYYQPSLTAE---YDEDS-PGGDFDFFSNLVTKWEAAARL----- 145
Query: 176 AWEFLEENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLSPEDKIPEL 235
V V G + L+ + L
Sbjct: 146 ---------PGDSTRQVVVRSGVVLG------RGGGAMGH--MLLPFRLGLGGPIGSGHQ 188
Query: 236 FGGYIDVRDVAKAHLVAFQKRETIGQRLIVSEARFTMQDVLDIL 279
F +I + D+A A + G V+ + T +
Sbjct: 189 FFPWIHIGDLAGILTHALEANHVHGVLNGVAPSSATNAEFAQTF 232
>3PPI-A nrPDB
Length = 281
Score = 40.7 bits (93), Expect = 8e-04, Method: Composition-based stats.
Identities = 32/145 (22%), Positives = 51/145 (35%), Gaps = 17/145 (11%)
Query: 2 SVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKF-SMEVVPDISK 60
S VSG G + + V L + V+ + + EK + L + GN +F S V + S
Sbjct: 32 SAIVSGGAGGLGEATVRRLHADGLGVVIADLAAEKGKALADELGNRAEFVSTNVTSEDSV 91
Query: 61 LDAFDHVFQKHGKDIKIVLH----TASPFCFDITDSER-----DLLIPAVNGVKGILHSI 111
L A + Q +V H A + +NG + +
Sbjct: 92 LAAIEAANQLGRLRYAVVAHGGFGVAQRIVQRDGSPADMGGFTKTIDLYLNGTYNVARLV 151
Query: 112 KKYAADSVER-------VVLTSSYA 129
A + R +VLT+S A
Sbjct: 152 AASIAAAEPRENGERGALVLTASIA 176
>6CI9-A nrPDB
Length = 259
Score = 39.9 bits (91), Expect = 0.001, Method: Composition-based stats.
Identities = 27/137 (19%), Positives = 47/137 (34%), Gaps = 11/137 (8%)
Query: 2 SVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKL 61
S V+G + I + I + V+ + R+Q+ + V D++
Sbjct: 11 SAIVTGGSKGIGRGIAETFANAGVDVVITGRNQDDLDRTVADLSGTRGKVTAVRADVTDP 70
Query: 62 D----AFDHVFQKHGKDIKIVLHTASPFCFD-----ITDSERDLLIPAVNGVKGILHS-I 111
+ +HG + IV A F D +L G I+ + +
Sbjct: 71 EDARRTVAETVSRHG-GLDIVCANAGIFPSGRLEDLTPDDIEQVLGVNFKGTVYIVQAAL 129
Query: 112 KKYAADSVERVVLTSSY 128
+ A RVV+TSS
Sbjct: 130 QALTASGHGRVVVTSSI 146
>5CDY-A nrPDB
Length = 244
Score = 39.5 bits (90), Expect = 0.002, Method: Composition-based stats.
Identities = 30/138 (21%), Positives = 60/138 (43%), Gaps = 6/138 (4%)
Query: 4 FVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKLDA 63
V+GA+ I + I +LL++ VIG+A S++ AE ++ G N K M V D + +D
Sbjct: 9 LVTGASRGIGRAIAELLVERGACVIGTATSEKGAEAISAYLGENGKGLMLNVVDPTSIDT 68
Query: 64 FDHVFQKHGKDIKIVLH----TASPFCFDITDSE-RDLLIPAVNGVKGILHSI-KKYAAD 117
+ ++ I+++ T + D E +D++ + V + ++ +
Sbjct: 69 VLATIRAEFGEVDILVNNAGITRDNLLMRMKDDEWQDIIDTNLTSVFRLSKAVMRAMMKK 128
Query: 118 SVERVVLTSSYAAVFDMA 135
R++ S A
Sbjct: 129 RFGRIITIGSVVGTMGNA 146
>2NM0-A nrPDB
Length = 253
Score = 39.5 bits (90), Expect = 0.002, Method: Composition-based stats.
Identities = 28/142 (19%), Positives = 43/142 (30%), Gaps = 22/142 (15%)
Query: 2 SVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISK- 60
SV V+G N I I KV + RS G P+ + V DI+
Sbjct: 23 SVLVTGGNRGIGLAIARAFADAGDKVAITYRS-----------GEPPEGFLAVKCDITDT 71
Query: 61 ---LDAFDHVFQKHGK-----DIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSI- 111
A+ + + HG V D ++ + G ++
Sbjct: 72 EQVEQAYKEIEETHGPVEVLIANAGVTKDQLLMRMSEEDF-TSVVETNLTGTFRVVKRAN 130
Query: 112 KKYAADSVERVVLTSSYAAVFD 133
+ RVVL SS +
Sbjct: 131 RAMLRAKKGRVVLISSVVGLLG 152
>1Q7C-A nrPDB
Length = 244
Score = 39.5 bits (90), Expect = 0.002, Method: Composition-based stats.
Identities = 41/247 (16%), Positives = 92/247 (37%), Gaps = 26/247 (10%)
Query: 4 FVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKLDA 63
V+GA+ I + I + L KVIG+A S+ A+ +++ G N K M V D + +++
Sbjct: 9 LVTGASRGIGRAIAETLAARGAKVIGTATSENGAQAISDYLGANGKGLMLNVTDPASIES 68
Query: 64 FDHVFQKHGKDIKIVLH----TASPFCFDITDSE-RDLLIPAVNGVKGILHSIKKYAADS 118
+ ++ I+++ T + D E D++ ++ V + ++ +
Sbjct: 69 VLEKIRAEFGEVDILVNNAGITRDNLLMRMKDEEWNDIIETNLSSVFRLSKAVMRAMMKK 128
Query: 119 VE-RVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAAW 177
R++ S A + + ++ + SK A + A
Sbjct: 129 RHGRIITIGSVVGTMGNG--------------GQANFAAAKAGLI---GFSKSLAREVAS 171
Query: 178 EFLEENRDSVKFELTAVNPVYV--FGPQMFDKDVKKHLNTSCELVNSLMHLSPEDKIPEL 235
+ N + F T + + + L + E+ N++ L+ ++ +
Sbjct: 172 RGITVNVVAPGFIETDMTRALSDDQRAGILAQVPAGRLGGAQEIANAVAFLASDEA-AYI 230
Query: 236 FGGYIDV 242
G + V
Sbjct: 231 TGETLHV 237
>3RSH-A nrPDB
Length = 251
Score = 39.1 bits (89), Expect = 0.003, Method: Composition-based stats.
Identities = 25/138 (18%), Positives = 57/138 (41%), Gaps = 6/138 (4%)
Query: 4 FVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKLDA 63
V+GA+ I + I +LL + KVIG+A S+ A+ +++ G+N K V + ++A
Sbjct: 16 LVTGASRGIGKAIAELLAERGAKVIGTATSESGAQAISDYLGDNGKGMALNVTNPESIEA 75
Query: 64 FDHVFQKHGKDIKIVLHTA-----SPFCFDITDSERDLLIPAVNGVKGILHSIKKYAADS 118
+ I+++ A + + D++ + + + ++ +
Sbjct: 76 VLKAITDEFGGVDILVNNAGITRDNLLMRMKEEEWSDIMETNLTSIFRLSKAVLRGMMKK 135
Query: 119 VE-RVVLTSSYAAVFDMA 135
+ R++ S A
Sbjct: 136 RQGRIINVGSVVGTMGNA 153
>3OSU-A nrPDB
Length = 246
Score = 38.3 bits (87), Expect = 0.004, Method: Composition-based stats.
Identities = 29/148 (19%), Positives = 60/148 (40%), Gaps = 11/148 (7%)
Query: 2 SVFVSGANGFIAQHIVDLLLKEDYKVIGSAR-SQEKAENLTEAFGNNPKFSMEVVPDISK 60
S V+GA+ I + I L +E Y V + S+EKAE + E S + +++
Sbjct: 6 SALVTGASRGIGRSIALQLAEEGYNVAVNYAGSKEKAEAVVEEIKAKGVDSFAIQANVAD 65
Query: 61 LDAFDHVFQ---KHGKDIKIVLHTASPFC--FDITDSERDLLIPAVNGVKGILHSIKKYA 115
D + + + ++++ A + E++ +KG+ + I+K
Sbjct: 66 ADEVKAMIKEVVSQFGSLDVLVNNAGITRDNLLMRMKEQEWDDVIDTNLKGVFNCIQKAT 125
Query: 116 ADSVER-----VVLTSSYAAVFDMAKEN 138
+ + + L+S AV + + N
Sbjct: 126 PQMLRQRSGAIINLSSVVGAVGNPGQAN 153
>2DKN-A nrPDB
Length = 255
Score = 37.2 bits (84), Expect = 0.011, Method: Composition-based stats.
Identities = 43/225 (19%), Positives = 64/225 (28%), Gaps = 29/225 (12%)
Query: 1 MSVF-VSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDIS 59
MSV ++G+ I + +LL + + VIG R Q E G
Sbjct: 1 MSVIAITGSASGIGAALKELLARAGHTVIGIDRGQADIEADLSTPGGR------------ 48
Query: 60 KLDAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVN--GVKGILHSIKKYAA- 116
A V + G + ++ A L+ AVN GV +L + + +
Sbjct: 49 -ETAVAAVLDRCGGVLDGLVCCAGVGVTAANSG----LVVAVNYFGVSALLDGLAEALSR 103
Query: 117 -DSVERVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKA 175
V++ S A A+ + Q AY GSK A
Sbjct: 104 GQQPAAVIVGSIAATQPGAAELPMVEAMLAGDEARAIELAEQQGQTHLAYAGSKY----A 159
Query: 176 AWEFLEENRDSV---KFELTAVNPVYVFGPQMFDKDVKKHLNTSC 217
N L V P V P + S
Sbjct: 160 VTCLARRNVVDWAGRGVRLNVVAPGAVETPLLQASKADPRYGEST 204
>5F5N-A nrPDB
Length = 289
Score = 37.2 bits (84), Expect = 0.012, Method: Composition-based stats.
Identities = 25/162 (15%), Positives = 39/162 (24%), Gaps = 24/162 (14%)
Query: 2 SVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKL 61
++ V+GA G V LL V R A V D++
Sbjct: 3 TILVTGATGTQGGATVRALLARGRPVRALVRDPGTDAARALAAAG----VSLVTGDLNDQ 58
Query: 62 DAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAADSVER 121
+ D+ V + +E ++ AA V
Sbjct: 59 ASLRAAM----ADVHGVFSVQTFMTPGGLGAE----------LRQGRAVADAAAATGVRH 104
Query: 122 VVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVN 163
VV +S A + + E W P
Sbjct: 105 VVYSSVGGA------DRASGVPHFETKWTIERHLRSLGVPTT 140
>5ILO-A nrPDB
Length = 271
Score = 36.8 bits (83), Expect = 0.013, Method: Composition-based stats.
Identities = 21/97 (21%), Positives = 41/97 (42%), Gaps = 6/97 (6%)
Query: 5 VSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVP-DISKLDA 63
V+G G I + LL + Q+ E + +P S+ ++ D++
Sbjct: 20 VTGGAGGIGLQVSKQLLAAGAAKVAIIDLQDNLEEFVKLRAAHPTQSVMIIKMDVANKKG 79
Query: 64 FDHVFQKHGK---DIKIVLHTASPFCFDITDSERDLL 97
+ +++ K +I IV++ A F+ D +R LL
Sbjct: 80 VEATYEEIAKTFGNIDIVVNVAGI--FNDKDVQRTLL 114
>1HE4-A nrPDB
Length = 206
Score = 36.4 bits (82), Expect = 0.018, Method: Composition-based stats.
Identities = 23/147 (15%), Positives = 48/147 (32%), Gaps = 19/147 (12%)
Query: 3 VFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKLD 62
+ + GA G + ++ Y+V R + P+ + VV D+ +
Sbjct: 6 IAIFGATGQTGLTTLAQAVQAGYEVTVLVRDSSR------LPSEGPRPAHVVVGDVLQAA 59
Query: 63 AFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAADSVERV 122
D V+ + R+ L P +G + + A V++V
Sbjct: 60 DVDKTV----AGQDAVI---------VLLGTRNDLSPTTVMSEGARNIVAAMKAHGVDKV 106
Query: 123 VLTSSYAAVFDMAKENDKSLTFNEESW 149
V +S ++D K + ++
Sbjct: 107 VACTSAFLLWDPTKVPPRLQAVTDDHI 133
>5ITV-A nrPDB
Length = 255
Score = 36.0 bits (81), Expect = 0.024, Method: Composition-based stats.
Identities = 36/249 (14%), Positives = 78/249 (31%), Gaps = 43/249 (17%)
Query: 2 SVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKL 61
+V ++G I V L + V+ + + + E + NN + V DI+
Sbjct: 9 TVLITGGASGIGYAAVQAFLGQQANVVVADIDEAQGEAMVRKE-NNDRLHF-VQTDITDE 66
Query: 62 DAFDHVFQKHG---KDIKIVLHTA-----SPFCFDITDSERDLLIPAVNGV-KGILHSIK 112
A H + + ++++ A +P +L + G+ H++K
Sbjct: 67 AACQHAVESAVHTFGGLDVLINNAGIEIVAPIHEMELSDWNKVLQVNLTGMFLMSKHALK 126
Query: 113 KYAADSVERVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFA 172
A ++ T S + W + V +
Sbjct: 127 HMLAAGKGNIINTCSVGGLVA---------------WPDIPAYNASKGGVL------QLT 165
Query: 173 EKAAWEFLEENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCEL------VNSLMHL 226
+ A ++ + + V P + P ++ + T E+ VN L+ L
Sbjct: 166 KSMAVDYAKHQ-----IRVNCVCPGIIDTPLNEKSFLENNEGTLEEIKKEKAKVNPLLRL 220
Query: 227 SPEDKIPEL 235
++I +
Sbjct: 221 GKPEEIANV 229
>3LYL-A nrPDB
Length = 247
Score = 36.0 bits (81), Expect = 0.025, Method: Composition-based stats.
Identities = 24/144 (16%), Positives = 51/144 (35%), Gaps = 9/144 (6%)
Query: 4 FVSGANGFIAQHIVDLLLKEDYKVIGSARSQ---EKAENLTEAFGNNPKFSMEVVPDISK 60
V+GA+ I + L + V+G+A SQ EK EN + G + + + DI
Sbjct: 9 LVTGASRGIGFEVAHALASKGATVVGTATSQASAEKFENSMKEKGFKARGLVLNISDIES 68
Query: 61 LDAFDHVFQKHGKDIKIVLHTA-----SPFCFDITDSERDLLIPAVNGVKGILHSIKKYA 115
+ F + I I+++ A + D + ++ ++ + + +
Sbjct: 69 IQNFFAEIKAENLAIDILVNNAGITRDNLMMRMSEDEWQSVINTNLSSIFRMSKECVRGM 128
Query: 116 ADSV-ERVVLTSSYAAVFDMAKEN 138
R++ S +
Sbjct: 129 MKKRWGRIISIGSVVGSAGNPGQT 152
>1QYC-A nrPDB
Length = 308
Score = 36.0 bits (81), Expect = 0.025, Method: Composition-based stats.
Identities = 26/174 (14%), Positives = 51/174 (29%), Gaps = 25/174 (14%)
Query: 2 SVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTE---AFGNNPKFSMEVVPDI 58
+ + GA G+I +H+ L + R + N + + V I
Sbjct: 6 RILLIGATGYIGRHVAKASLDLGHPTFLLVRESTASSNSEKAQLLESFKASGANIVHGSI 65
Query: 59 SKLDAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAADS 118
+ K++ +V+ T + I+ +IK+ +
Sbjct: 66 DDHASLVEAV----KNVDVVISTVGSLQIESQ--------------VNIIKAIKE--VGT 105
Query: 119 VERVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFA 172
V+R S + D + + + E + P Y S FA
Sbjct: 106 VKRF-FPSEFGNDVDNVHAVEPAKSVFEVKAKVRRAIEAEGIPYT-YVSSNCFA 157
>2GGS-A nrPDB
Length = 273
Score = 35.6 bits (80), Expect = 0.031, Method: Composition-based stats.
Identities = 56/327 (17%), Positives = 111/327 (33%), Gaps = 58/327 (17%)
Query: 1 MSVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISK 60
M ++GA+G + + LL + ++VI S E + P+ ++
Sbjct: 1 MRTLITGASGQLGIELSRLLSER-HEVIKVYNSSEIQGGYKLDLTDFPRLEDFIIK---- 55
Query: 61 LDAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAADSVE 120
K ++++ A+ D + E++ + + H ++ A ++
Sbjct: 56 ------------KRPDVIINAAAMTDVDKCEIEKE--KAYKINAEAVRHIVR--AGKVID 99
Query: 121 RVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAAWEFL 180
++ S VFD K N K +P+N Y SK E A +
Sbjct: 100 SYIVHISTDYVFDGEKGNYKEEDIP--------------NPINYYGLSKLLGETFALQD- 144
Query: 181 EENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLSPEDKIPELFGGYI 240
+ + +F + F V K L + + SP I
Sbjct: 145 ---------DSLIIRTSGIFRNKGFPIYVYKTLKEGKTVFAFKGYYSP-----------I 184
Query: 241 DVRDVAKAHLVAFQKRETIGQRLIVSEARFTMQDVLDILNEDFPVLKGNIPVGKPGSGAT 300
R +A A L + R+T + V+ R + ++ + E F + V +
Sbjct: 185 SARKLASAILELLELRKT--GIIHVAGERISRFELALKIKEKFNLPGEVKEVDEVRGWIA 242
Query: 301 HNTLGATLDNKKSKKLLGFKFRNLKET 327
++LD+ +++K+L F L
Sbjct: 243 KRPYDSSLDSSRARKILSTDFYTLDLD 269
>3UN1-A nrPDB
Length = 260
Score = 35.3 bits (79), Expect = 0.041, Method: Composition-based stats.
Identities = 25/124 (20%), Positives = 45/124 (36%), Gaps = 17/124 (13%)
Query: 3 VFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKLD 62
V ++GA+ I +V +Y+V+ ++RS + + + P V DISK +
Sbjct: 31 VVITGASQGIGAGLVRAYRDRNYRVVATSRSIKPSAD--------PDIHT-VAGDISKPE 81
Query: 63 AFDHV----FQKHGKDIKIV----LHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKY 114
D + ++ G+ +V + A PF + L V G I
Sbjct: 82 TADRIVREGIERFGRIDSLVNNAGVFLAKPFVEMTQEDYDHNLGVNVAGFFHITQRAAAE 141
Query: 115 AADS 118
Sbjct: 142 MLKQ 145
>5LCX-A nrPDB
Length = 316
Score = 35.3 bits (79), Expect = 0.042, Method: Composition-based stats.
Identities = 17/86 (19%), Positives = 35/86 (40%), Gaps = 7/86 (8%)
Query: 4 FVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFG-------NNPKFSMEVVP 56
V+GAN I I L ++ VI ++R++++ + N F V
Sbjct: 11 LVTGANKGIGFEICRQLAEKGIIVILTSRNEKRGLEARQKLLKELNVSENRLVFHQLDVT 70
Query: 57 DISKLDAFDHVFQKHGKDIKIVLHTA 82
D++ + A + + I+++ A
Sbjct: 71 DLASVAAVAVFIKSKFGKLDILVNNA 96
>5GXF-A nrPDB
Length = 330
Score = 34.9 bits (78), Expect = 0.048, Method: Composition-based stats.
Identities = 12/41 (29%), Positives = 17/41 (41%)
Query: 3 VFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEA 43
V V+GA G + +L Y+V E A+ LT
Sbjct: 153 VLVTGAAGGVGSVATAILAHLGYEVAAVTGRPETADYLTSL 193
>4IIV-A nrPDB
Length = 267
Score = 34.9 bits (78), Expect = 0.049, Method: Composition-based stats.
Identities = 20/150 (13%), Positives = 45/150 (30%), Gaps = 23/150 (15%)
Query: 2 SVFVSGANGFIAQHIVDLLLKEDY---------------KVIGSARSQEKAENLTEAFGN 46
SV V+GA+ I + I L + + + + L+ N
Sbjct: 28 SVLVTGASKGIGRAIARQLAADGFNIGVHYHRDAAGAQETLNAIVANGGNGRLLSFDVAN 87
Query: 47 NPKFSMEVVPDISKLDAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKG 106
+ + +I++ A+ V G S D ++ ++
Sbjct: 88 REQCREVLEHEIAQHGAWYGVVSNAGIARDAAFPALS------NDDWDAVIHTNLDSFYN 141
Query: 107 ILHSIKKYAADSVE--RVVLTSSYAAVFDM 134
++ + + R++ SS + V
Sbjct: 142 VIQPCIMPMIGARQGGRIITLSSVSGVMGN 171
>1CYD-A nrPDB
Length = 244
Score = 34.9 bits (78), Expect = 0.054, Method: Composition-based stats.
Identities = 46/259 (17%), Positives = 73/259 (28%), Gaps = 37/259 (14%)
Query: 1 MSVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISK 60
+ V+GA I + V L KV+ R +L P V D+
Sbjct: 8 LRALVTGAGKGIGRDTVKALHASGAKVVAVTR---TNSDLVSLAKECPGIEPVCV-DLGD 63
Query: 61 LDAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAADSVE 120
DA + G + ++++ A+ ++ P + K
Sbjct: 64 WDATEKALGGIGP-VDLLVNNAALV----------IMQPFLEVTKEAFDRSFSVNL---- 108
Query: 121 RVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAAWEFL 180
R V S DM N S + Y S K A + +
Sbjct: 109 RSVFQVSQMVARDMINRGVPGSIVNVSS----MVAHVTFPNLITYS-STKGAMTMLTKAM 163
Query: 181 EENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLSPEDKIPELFGGYI 240
K + +VNP V D+ K ++ E L P K +
Sbjct: 164 AMELGPHKIRVNSVNPTVVL------TDMGKKVSADPEFARKLKERHPLRK-------FA 210
Query: 241 DVRDVAKAHLVAFQKRETI 259
+V DV + L R
Sbjct: 211 EVEDVVNSILFLLSDRSAS 229
>1GFS-A nrPDB
Length = 321
Score = 34.9 bits (78), Expect = 0.055, Method: Composition-based stats.
Identities = 43/299 (14%), Positives = 93/299 (31%), Gaps = 60/299 (20%)
Query: 2 SVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKL 61
VF++G G + I L + V R++++ L V D
Sbjct: 5 RVFIAGHRGMVGSAIRRQLEQRG-DVELVLRTRDELNLLDSR----------AVHDFFAS 53
Query: 62 DAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAADSVER 121
+ D V+ K IV + P F ++++I + + I + V +
Sbjct: 54 ERIDQVYLAAAKVGGIVANNTYPADF----IYQNMMIES--------NIIHAAHQNDVNK 101
Query: 122 VVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVN-AYCGSKKFAEKAAWEFL 180
++ S + ++ E +P N Y A+ A +
Sbjct: 102 LLFLGS-SCIY----PKLAKQPMAES-----ELLQGTLEPTNEPYA----IAKIAGIKLC 147
Query: 181 EENRDSVKFELTAVNPVYVFGPQMFDKDVKKHL---------NTSCELVNSLMHLSPEDK 231
E + +V P ++GP H+ + + ++
Sbjct: 148 ESYNRQYGRDYRSVMPTNLYGPHDNFHPSNSHVIPALLRRFHEATAQNAPDVVVWGSGTP 207
Query: 232 IPELFGGYIDVRDVA--------KAHLVAFQKRETIGQRLIVSEAR-FTMQDVLDILNE 281
+ E ++ V D+A AH V + + + + V T++++ + +
Sbjct: 208 MRE----FLHVDDMAAASIHVMELAHEVWLENTQPMLSHINVGTGVDCTIRELAQTIAK 262
>2J3K-A nrPDB
Length = 345
Score = 34.9 bits (78), Expect = 0.057, Method: Composition-based stats.
Identities = 19/58 (32%), Positives = 32/58 (55%)
Query: 2 SVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDIS 59
+V+VS A+G + Q + L V+GSA S+EK + L FG + F+ + D++
Sbjct: 158 TVYVSAASGAVGQLVGQLAKMMGCYVVGSAGSKEKVDLLKTKFGFDDAFNYKEESDLT 215
>4IIN-A nrPDB
Length = 271
Score = 34.5 bits (77), Expect = 0.062, Method: Composition-based stats.
Identities = 14/68 (20%), Positives = 24/68 (35%), Gaps = 1/68 (1%)
Query: 3 VFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVP-DISKL 61
V ++GA+ I I L KV + RS + + + + V+ D +
Sbjct: 32 VLITGASKGIGAEIAKTLASMGLKVWINYRSNAEVADALKNELEEKGYKAAVIKFDAASE 91
Query: 62 DAFDHVFQ 69
F Q
Sbjct: 92 SDFIEAIQ 99
>3F9I-A nrPDB
Length = 249
Score = 34.5 bits (77), Expect = 0.072, Method: Composition-based stats.
Identities = 31/139 (22%), Positives = 57/139 (41%), Gaps = 8/139 (5%)
Query: 2 SVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKL 61
+ ++GA+ I I LL K KVI S ++EK ++L A +N V +++
Sbjct: 16 TSLITGASSGIGSAIARLLHKLGSKVIISGSNEEKLKSLGNALKDN---YTIEVCNLANK 72
Query: 62 DAFDHVFQKHGKDIKIVLH---TASPFCFDITDSERDLLIPAVNGVKGILH--SIKKYAA 116
+ ++ K +V + T+ + D + D +I IL+ +IKK
Sbjct: 73 EECSNLISKTSNLDILVCNAGITSDTLAIRMKDQDFDKVIDINLKANFILNREAIKKMIQ 132
Query: 117 DSVERVVLTSSYAAVFDMA 135
R++ SS +
Sbjct: 133 KRYGRIINISSIVGIAGNP 151
>1AE1-A nrPDB
Length = 273
Score = 33.7 bits (75), Expect = 0.11, Method: Composition-based stats.
Identities = 37/241 (15%), Positives = 88/241 (36%), Gaps = 31/241 (12%)
Query: 2 SVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKL 61
+ V+G + I IV+ L +V +R++++ + E + V D+
Sbjct: 23 TALVTGGSKGIGYAIVEELAGLGARVYTCSRNEKELDECLEIWREKGLNVEGSVCDLLSR 82
Query: 62 DAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAADSVER 121
D + Q V H + D + ++L VN ++H K +
Sbjct: 83 TERDKLMQ-------TVAH--------VFDGKLNIL---VNNAGVVIHKEAKDFTEKDYN 124
Query: 122 VVLTSSYAAVFDMAKENDKSLTFNEES---WNPATWESCQSDPVNAYCGSK----KFAEK 174
+++ +++ A + +++ L ++ + + V+ Y SK + +
Sbjct: 125 IIMGTNFEAAYHLSQIAYPLLKASQNGNVIFLSSIAGFSALPSVSLYSASKGAINQMTKS 184
Query: 175 AAWEFLEENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLSPEDKIPE 234
A E+ ++N + +V P + P + +KK+ + E+ N ++
Sbjct: 185 LACEWAKDN-----IRVNSVAPGVILTPLVETA-IKKNPHQKEEIDNFIVKTPMGRAGKP 238
Query: 235 L 235
Sbjct: 239 Q 239
>4CQM-B nrPDB
Length = 244
Score = 33.7 bits (75), Expect = 0.11, Method: Composition-based stats.
Identities = 35/257 (13%), Positives = 95/257 (36%), Gaps = 31/257 (12%)
Query: 3 VF-VSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLT-EAFGNNPKFSMEVVPDISK 60
V V G + I + + L+ ++ Y++ AR+ E A+ + G++ FS +V +
Sbjct: 11 VCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHDV 70
Query: 61 LDAFDHVFQKHGKDIKIVLHTASPFC--FDITDSERDLLIPAVNGVKGILHSIKKYAADS 118
+ F+ +KH + +++ A + D++ + G + + K
Sbjct: 71 QNTFEE-LEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRTM 129
Query: 119 VER----VVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEK 174
+++ +V + ++ + + +S+ S + + S+ A++
Sbjct: 130 IQQQGGSIV---NVGSIVGLKGNSGQSVY------------SASKGGLVGF--SRALAKE 172
Query: 175 AAWEFLEENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLSPEDKIPE 234
A + + N + F T + + + + E+ ++++ L
Sbjct: 173 VARKKIRVNVVAPGFVHTDMTK-DLKEEHLKKNIPLGRFGETIEVAHAVVFLLES----P 227
Query: 235 LFGGYIDVRDVAKAHLV 251
G++ V D ++
Sbjct: 228 YITGHVLVVDGGLQLIL 244
>2Q4B-A nrPDB
Length = 253
Score = 33.7 bits (75), Expect = 0.13, Method: Composition-based stats.
Identities = 31/148 (20%), Positives = 50/148 (33%), Gaps = 20/148 (13%)
Query: 2 SVFVSGANGFIAQHIVDLLLK--EDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDIS 59
+V V+GA+G Q + L + + + G RS + E G + DI+
Sbjct: 6 TVLVTGASGRTGQIVYKKLKEGSDKFVAKGLVRSAQG----KEKIGGEADV---FIGDIT 58
Query: 60 KLDAFDHVFQKHGKDIKIVLHTASPFCFDITDSE---------RDLLIPAVNGVKGILHS 110
D+ + FQ G D ++L +A P D D P G +
Sbjct: 59 DADSINPAFQ--GIDALVILTSAVPKMKPGFDPTKGGRPEFIFEDGQYPEQVDWIGQKNQ 116
Query: 111 IKKYAADSVERVVLTSSYAAVFDMAKEN 138
I V+ +V+ S N
Sbjct: 117 IDAAKVAGVKHIVVVGSMGGTNPDHPLN 144
>4KTT-E nrPDB
Length = 327
Score = 33.3 bits (74), Expect = 0.16, Method: Composition-based stats.
Identities = 55/339 (16%), Positives = 105/339 (30%), Gaps = 57/339 (16%)
Query: 2 SVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKL 61
V V+GA G + + + + ++ +G PKF ++
Sbjct: 23 RVLVTGATGLLGRAVHKEFQQNNWHAVGC-----------GFRRARPKFEQV---NLLDS 68
Query: 62 DAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAADSVER 121
+A H+ + ++H A+ D+ +++ D A ++ K AA
Sbjct: 69 NAVHHIIHDFQPHV--IVHCAAERRPDVVENQPDA---ASQLNVDASGNLAKEAAAVGAF 123
Query: 122 VVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAAWEFLE 181
++ SS F+ NP E P+N Y +K EKA
Sbjct: 124 LIYISS-------------DYVFDGT--NPPYREEDIPAPLNLYGKTKLDGEKAVL---- 164
Query: 182 ENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLSPEDKIPELFGGY-- 239
EN + +V+K ++ ++ + S + + +
Sbjct: 165 ENNLGAAVLRIPILY----------GEVEKLEESAVTVMFDKVQFSNKSANMDHWQQRFP 214
Query: 240 IDVRDVAKAHLVAFQK----RETIGQRLIVSEARFTMQDVLDILNEDF--PVLKGNIPVG 293
V+DVA +K G + T ++ + + F P
Sbjct: 215 THVKDVATVCRQLAEKRMLDPSIKGTFHWSGNEQMTKYEMACAIADAFNLPSSHLRPITD 274
Query: 294 KPGSGATHNTLGATLDNKKSKKLLGFKFRNLKETIDDTA 332
P GA A LD K + L + + I ++
Sbjct: 275 SPVLGAQRPR-NAQLDCSKLETLGIGQRTPFRIGIKESL 312
>2QYS-A nrPDB
Length = 318
Score = 33.3 bits (74), Expect = 0.16, Method: Composition-based stats.
Identities = 13/77 (16%), Positives = 30/77 (38%), Gaps = 6/77 (7%)
Query: 3 VFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKLD 62
+ + G G+I H+V LK + R L + F + ++ V ++ + +
Sbjct: 14 ILIFGGTGYIGNHMVKGSLKLGHPTYVFTRPNSSKTTLLDEFQSLG--AIIVKGELDEHE 71
Query: 63 AFDHVFQKHGKDIKIVL 79
+ K + +V+
Sbjct: 72 KLVELM----KKVDVVI 84
>3SC6-A nrPDB
Length = 287
Score = 32.9 bits (73), Expect = 0.18, Method: Composition-based stats.
Identities = 51/318 (16%), Positives = 99/318 (31%), Gaps = 57/318 (17%)
Query: 2 SVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKL 61
V ++GANG + + + + L E+Y + + L DI+ +
Sbjct: 7 RVIITGANGQLGKQLQEELNPEEYDIY-----PFDKKLL----------------DITNI 45
Query: 62 DAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAADSVER 121
V Q+ I ++H A+ D + ERDL V G + +
Sbjct: 46 SQVQQVVQEIRPHI--IIHCAAYTKVDQAEKERDLA--YVINAIGARNVAVASQLVGAKL 101
Query: 122 VVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAAWEFLE 181
V +++ Y VF + ++E P+N Y SK E+ F++
Sbjct: 102 VYISTDY--VFQGDRPEG----YDEFH---------NPAPINIYGASKYAGEQ----FVK 142
Query: 182 ENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLSPEDKIPELFGGYID 241
E + V +++G K N ++ + + G
Sbjct: 143 ELHNKYFI----VRTSWLYG--------KYGNNFVKTMIRLGKEREEISVVADQIGSPTY 190
Query: 242 VRDVAKAHLVAFQKRETIGQRLIVSEARFTMQDVLDILNEDFPVLKGNIPVGKPGSGATH 301
V D+ + G + + + + + + +PV GA
Sbjct: 191 VADL-NVMINKLIHTSLYGTYHVSNTGSCSWFEFAKKIFSYANMKVNVLPVSTEEFGAAA 249
Query: 302 NTLGATLDNKKSKKLLGF 319
++ +L GF
Sbjct: 250 ARPKYSIFQHNMLRLNGF 267
>1DXY-A nrPDB
Length = 333
Score = 32.9 bits (73), Expect = 0.20, Method: Composition-based stats.
Identities = 25/121 (20%), Positives = 42/121 (34%), Gaps = 15/121 (12%)
Query: 2 SVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKL 61
+V V G G I Q + L KVI K G++P F + D+ K
Sbjct: 147 TVGVMG-TGHIGQVAIKLFKGFGAKVIAYDPYPMK--------GDHPDFDYVSLEDLFKQ 197
Query: 62 DAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLL---IPAVNGVKGILHSIKKYAADS 118
V H I+ H + F++ ++ P + + +L ++K
Sbjct: 198 S---DVIDLHVPGIEQNTHIINEAAFNLMKPGAIVINTARPNLIDTQAMLSNLKSGKLAG 254
Query: 119 V 119
V
Sbjct: 255 V 255
>2AE2-A nrPDB
Length = 260
Score = 32.9 bits (73), Expect = 0.20, Method: Composition-based stats.
Identities = 29/146 (19%), Positives = 51/146 (34%), Gaps = 10/146 (6%)
Query: 2 SVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKL 61
+ V+G + I IV+ L V +R+Q++ + + + V D+S
Sbjct: 11 TALVTGGSRGIGYGIVEELASLGASVYTCSRNQKELNDCLTQWRSKGFKVEASVCDLSSR 70
Query: 62 DAFDHVF-----QKHGKDIKIVLHTASPFCFDITDS--ERDLLIPAVN-GVKGILHSIKK 113
+ HGK +V + + D E LI ++N L +
Sbjct: 71 SERQELMNTVANHFHGKLNILVNNAGIVIYKEAKDYTVEDYSLIMSINFEAAYHLSVLAH 130
Query: 114 YAADSVER--VVLTSSYAAVFDMAKE 137
+ ER VV SS + + E
Sbjct: 131 PFLKASERGNVVFISSVSGALAVPYE 156
>1V3V-A nrPDB
Length = 333
Score = 32.6 bits (72), Expect = 0.23, Method: Composition-based stats.
Identities = 20/79 (25%), Positives = 35/79 (44%), Gaps = 7/79 (8%)
Query: 2 SVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISK- 60
+V VS A G + + + + KV+G+A S EK L + G + F+ + V + +
Sbjct: 148 TVLVSAAAGAVGSVVGQIAKLKGCKVVGAAGSDEKIAYLKQ-IGFDAAFNYKTVNSLEEA 206
Query: 61 -----LDAFDHVFQKHGKD 74
D +D F G +
Sbjct: 207 LKKASPDGYDCYFDNVGGE 225
>3DWF-A nrPDB
Length = 276
Score = 32.6 bits (72), Expect = 0.24, Method: Composition-based stats.
Identities = 25/136 (18%), Positives = 45/136 (33%), Gaps = 9/136 (6%)
Query: 3 VFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKLD 62
V V+GA+ I + I L K V+ +ARS+E + + S + +
Sbjct: 14 VIVTGASKGIGREIAYHLAKMGAHVVVTARSKEALQKVVARCLELGAASAHYIAGSMEDM 73
Query: 63 AFDHVFQKHGKDIKI---------VLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKK 113
F F ++ VL+ F D+ R + + + +
Sbjct: 74 TFAEEFVAEAGNLMGGLDMLILNHVLYNRLTFFHGEIDNVRKSMEVNFHSFVVLSVAAMP 133
Query: 114 YAADSVERVVLTSSYA 129
S + + SS A
Sbjct: 134 MLMQSQGSIAVVSSVA 149
>1HXH-A nrPDB
Length = 253
Score = 32.6 bits (72), Expect = 0.24, Method: Composition-based stats.
Identities = 16/79 (20%), Positives = 29/79 (36%)
Query: 4 FVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKLDA 63
V+G + +V LLL E KV S ++ + L G F V +
Sbjct: 10 LVTGGASGVGLEVVKLLLGEGAKVAFSDINEAAGQQLAAELGERSMFVRHDVSSEADWTL 69
Query: 64 FDHVFQKHGKDIKIVLHTA 82
Q+ + ++++ A
Sbjct: 70 VMAAVQRRLGTLNVLVNNA 88
>1VL0-A nrPDB
Length = 292
Score = 32.6 bits (72), Expect = 0.28, Method: Composition-based stats.
Identities = 49/337 (14%), Positives = 107/337 (31%), Gaps = 68/337 (20%)
Query: 1 MSVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISK 60
M + ++GANG + + I L ++ +VI ++L DI+
Sbjct: 13 MKILITGANGQLGREIQKQLKGKNVEVI-----PTDVQDL----------------DITN 51
Query: 61 LDAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAADSVE 120
+ A + F + K +V++ A+ + E + G + AA SV
Sbjct: 52 VLAVNKFFNE--KKPNVVINCAA--HTAVDKCEEQYDLAYKINAIGPKNL--AAAAYSVG 105
Query: 121 RVVLTSSYAAVFDMAKENDKSLTFNEESWNPATWESCQSDPVNAYCGSKKFAEKAAWEFL 180
++ S VFD + + F+E + P +AY +K E F+
Sbjct: 106 AEIVQISTDYVFD-GEAKEPITEFDEVN------------PQSAYGKTKLEGE----NFV 148
Query: 181 EENRDSVKFELTAVNPVYVFGPQMFDKDVKKHLNTSCELVNSLMHLSPEDKIPELFGGYI 240
+ V +++G + VK +N + + + + G
Sbjct: 149 KALNPKYYI----VRTAWLYGD--GNNFVKTMINLG--KTHDELKVVHDQ-----VGTPT 195
Query: 241 DVRDVAKAHLVAFQKRETIGQRLIVSEARFTMQDV-LDILN------EDFPVLKGNIPVG 293
D+A+ L ++ + + D ++I + P P
Sbjct: 196 STVDLARVVLKVIDEKNYGTFHCTC-KGICSWYDFAVEIFRLTGIDVKVTPCTTEEFPRP 254
Query: 294 KPGSGATHNTLGATLDNKKSKKLLGFKFRNLKETIDD 330
++ + + + +++ + D
Sbjct: 255 AK---RPKYSVLRNYMLELTTGDITREWKESLKEYID 288
>1O89-A nrPDB
Length = 345
Score = 32.6 bits (72), Expect = 0.28, Method: Composition-based stats.
Identities = 17/70 (24%), Positives = 28/70 (40%), Gaps = 5/70 (7%)
Query: 3 VFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNN--PKFSMEVVPDISK 60
+ V+GA+G + V LL K Y+V+ + + E L + P+ + K
Sbjct: 171 IVVTGASGGVGSTAVALLHKLGYQVVAVSGRESTHEYLKSLGASRVLPRDEFAESRPLEK 230
Query: 61 L---DAFDHV 67
A D V
Sbjct: 231 QVWAGAIDTV 240
>6G2J-P nrPDB
Length = 377
Score = 32.6 bits (72), Expect = 0.29, Method: Composition-based stats.
Identities = 28/145 (19%), Positives = 51/145 (35%), Gaps = 15/145 (10%)
Query: 5 VSGANGFIAQHIVDLLLKEDYKVIGSAR-SQEKAENLTEAFGNNPKFSMEVVPDISKLDA 63
V GA GF+ +++V+ L + +VI R +L G+ + + + D D+
Sbjct: 58 VFGATGFLGRYVVNHLGRMGSQVIIPYRCDVYDIMHLR-LMGDLGQLTF-LEWDARDKDS 115
Query: 64 FDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSI-KKYAADSVERV 122
Q I ++ FD D I +I + VER
Sbjct: 116 IRKAVQHSNVVINLIGREWETRNFDFEDV-----------FVNIPRAIAQASKEAGVERF 164
Query: 123 VLTSSYAAVFDMAKENDKSLTFNEE 147
+ S A + ++ +S E+
Sbjct: 165 IHVSHLNASMKSSSKSLRSKAVGEK 189
>3D3W-A nrPDB
Length = 244
Score = 32.2 bits (71), Expect = 0.32, Method: Composition-based stats.
Identities = 37/201 (18%), Positives = 68/201 (33%), Gaps = 28/201 (13%)
Query: 2 SVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLT-EAFGNNPKFSMEVVPDISK 60
V V+GA I + V L +V+ +R+Q ++L E G P V D+
Sbjct: 9 RVLVTGAGKGIGRGTVQALHATGARVVAVSRTQADLDSLVRECPGIEP-----VCVDLGD 63
Query: 61 LDAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAADSVE 120
+A + G P + ++ LL P + K + + ++
Sbjct: 64 WEATERALGSVG-----------PVDLLVNNAAVALLQPFLEVTK---EAFDRSFEVNLR 109
Query: 121 RVVLTSSYAAVFDMAKENDKSLT-FNEESWNPATWESCQSDPVNAYCGSKKFAEKAAWEF 179
V+ S A +A+ ++ + + A YC +K + +
Sbjct: 110 AVIQVSQIVARGLIARGVPGAIVNVSSQCSQRAVTNHSV------YCSTKGALDM-LTKV 162
Query: 180 LEENRDSVKFELTAVNPVYVF 200
+ K + AVNP V
Sbjct: 163 MALELGPHKIRVNAVNPTVVM 183
>2B4Q-A nrPDB
Length = 276
Score = 32.2 bits (71), Expect = 0.37, Method: Composition-based stats.
Identities = 24/147 (16%), Positives = 49/147 (33%), Gaps = 14/147 (9%)
Query: 4 FVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKLDA 63
V+G + I Q I LL+ +V AR E + + D+S
Sbjct: 33 LVTGGSRGIGQMIAQGLLEAGARVFICARDAEACADTATRLSAYGDCQA-IPADLSSEAG 91
Query: 64 ---FDHVFQKHGKDIKIVLHTASPFCFDITDSE-----RDLLIPAVNGVKGILHSI---- 111
+ + I+++ A +S ++ V V + +
Sbjct: 92 ARRLAQALGELSARLDILVNNAGTSWGAALESYPVSGWEKVMQLNVTSVFSCIQQLLPLL 151
Query: 112 -KKYAADSVERVVLTSSYAAVFDMAKE 137
+ +A++ RV+ S A + M ++
Sbjct: 152 RRSASAENPARVINIGSVAGISAMGEQ 178
>5TQV-A nrPDB
Length = 233
Score = 32.2 bits (71), Expect = 0.37, Method: Composition-based stats.
Identities = 12/78 (15%), Positives = 27/78 (34%), Gaps = 3/78 (3%)
Query: 2 SVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKL 61
+V + GA+ + + V ++ + VI +AR L + ++
Sbjct: 11 TVLIVGASRGLGREFVRQYQRDGWNVIATARDDASLAALRAL---GAHAHALDITQPEQI 67
Query: 62 DAFDHVFQKHGKDIKIVL 79
A D+ +V+
Sbjct: 68 AALGWKLDGERLDVAVVV 85
>2YV2-A nrPDB
Length = 297
Score = 31.8 bits (70), Expect = 0.45, Method: Composition-based stats.
Identities = 16/87 (18%), Positives = 33/87 (37%), Gaps = 10/87 (11%)
Query: 2 SVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKA---------ENLTEAFGNNPKFSM 52
V V G G +L+ KV+ + +++ EA +P+ +
Sbjct: 15 RVLVQGITGREGSFHAKAMLEYGTKVVAGVTPGKGGSEVHGVPVYDSVKEALAEHPEINT 74
Query: 53 EVVPDISKLDAFDHVFQKHGKDIKIVL 79
+V + A D V++ I++V+
Sbjct: 75 SIVF-VPAPFAPDAVYEAVDAGIRLVV 100
>2Y05-A nrPDB
Length = 328
Score = 31.8 bits (70), Expect = 0.47, Method: Composition-based stats.
Identities = 18/79 (22%), Positives = 34/79 (43%), Gaps = 7/79 (8%)
Query: 2 SVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISK- 60
+V V+ A G + + + + KV+G+ S EK L + G + F+ + V + +
Sbjct: 143 TVMVNAAAGAVGSVVGQIAKLKGCKVVGAVGSDEKVAYLQKL-GFDVVFNYKTVESLEET 201
Query: 61 -----LDAFDHVFQKHGKD 74
D +D F G +
Sbjct: 202 LKKASPDGYDCYFDNVGGE 220
>2X9N-A nrPDB
Length = 288
Score = 31.4 bits (69), Expect = 0.57, Method: Composition-based stats.
Identities = 18/103 (17%), Positives = 37/103 (35%), Gaps = 12/103 (11%)
Query: 5 VSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVV--PDISK-- 60
V+GA I + I L + Y+V+ + +A N + + VV D++
Sbjct: 28 VTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTNSN 87
Query: 61 --LDAFDHVFQKH---GKDIKIVLHTAS---PFCFDITDSERD 95
+ + + ++++ AS P D E +
Sbjct: 88 VLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVQGDHEDN 130
>3GRP-A nrPDB
Length = 266
Score = 31.4 bits (69), Expect = 0.59, Method: Composition-based stats.
Identities = 21/144 (14%), Positives = 44/144 (30%), Gaps = 12/144 (8%)
Query: 4 FVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKLDA 63
V+GA G I + I + ++G + + L E + K ++S +
Sbjct: 31 LVTGATGGIGEAIARCFHAQG-AIVGL--HGTREDKLKEIAADLGKDVFVFSANLSDRKS 87
Query: 64 ---FDHVFQKHGKDIKIVLHTASP------FCFDITDSERDLLIPAVNGVKGILHSIKKY 114
V ++ + I I+++ A D + L + I
Sbjct: 88 IKQLAEVAEREMEGIDILVNNAGITRDGLFVRMQDQDWDDVLAVNLTAASTLTRELIHSM 147
Query: 115 AADSVERVVLTSSYAAVFDMAKEN 138
R++ +S V +
Sbjct: 148 MRRRYGRIINITSIVGVVGNPGQT 171
>4BO1-A nrPDB
Length = 269
Score = 31.0 bits (68), Expect = 0.69, Method: Composition-based stats.
Identities = 31/144 (21%), Positives = 56/144 (38%), Gaps = 9/144 (6%)
Query: 4 FVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKLDA 63
V+GA+ I Q I L + VIG+A S AE + E N +V D+S ++
Sbjct: 31 LVTGASRGIGQAIALELGRLGAVVIGTATSASGAEKIAETLKANGVEGAGLVLDVSSDES 90
Query: 64 FD---HVFQKHGKDIKIVLH----TASPFCFDITDSE-RDLLIPAVNGVKGILHSIKKYA 115
Q+H IV++ T + D E D++ +N + + ++ +
Sbjct: 91 VAATLEHIQQHLGQPLIVVNNAGITRDNLLVRMKDDEWFDVVNTNLNSLYRLSKAVLRGM 150
Query: 116 ADSV-ERVVLTSSYAAVFDMAKEN 138
+ R++ S A +
Sbjct: 151 TKARWGRIINIGSVVGAMGNAGQT 174
>1QYD-A nrPDB
Length = 313
Score = 31.0 bits (68), Expect = 0.84, Method: Composition-based stats.
Identities = 9/42 (21%), Positives = 17/42 (40%), Gaps = 1/42 (2%)
Query: 2 SVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEA 43
V + G G+I + IV+ + + R E N+ +
Sbjct: 6 RVLIVGGTGYIGKRIVNASISLGHPTYVLFR-PEVVSNIDKV 46
>5TZ8-A nrPDB
Length = 572
Score = 30.6 bits (67), Expect = 0.87, Method: Composition-based stats.
Identities = 26/129 (20%), Positives = 46/129 (35%), Gaps = 17/129 (13%)
Query: 88 DITDSERDLLIPAVNGV--KGILHSIKKYAADSVE----RVVLTSSYAAVFDMAKENDKS 141
I + D+L+ + GV +G+ S+ K A V R++ T S ++ A D
Sbjct: 107 FIDEHHSDVLLIKMKGVNGRGVPQSMFKETAPEVTLLNSRIIYTLSPTKIYRTALLKDND 166
Query: 142 LTFNEESWNPATWESCQSDPVNA-----------YCGSKKFAEKAAWEFLEENRDSVKFE 190
+ F EE + +NA Y +K+ E + ++
Sbjct: 167 IYFPEELKSAEDQLFTMKAYLNANRISVLSDKAYYYATKREGEHMSSAYVSPEDFYEVMR 226
Query: 191 LTAVNPVYV 199
L AV +
Sbjct: 227 LIAVEILNA 235
>5WQO-A nrPDB
Length = 234
Score = 30.6 bits (67), Expect = 0.92, Method: Composition-based stats.
Identities = 13/60 (21%), Positives = 24/60 (40%)
Query: 3 VFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKLD 62
V + GA+ I + D L+ +V AR + + L + V D+++ D
Sbjct: 9 VLIVGASRGIGLGLADAFLQRGAQVFAVARRPQGSPGLQALAERAGERLQAVTGDLNQHD 68
>2VCE-A nrPDB
Length = 480
Score = 30.6 bits (67), Expect = 0.92, Method: Composition-based stats.
Identities = 13/57 (22%), Positives = 22/57 (38%)
Query: 32 RSQEKAENLTEAFGNNPKFSMEVVPDISKLDAFDHVFQKHGKDIKIVLHTASPFCFD 88
RS + + ++F + +V D+ DAFD + H TA+ F
Sbjct: 92 RSNPELRKVFDSFVEGGRLPTALVVDLFGTDAFDVAVEFHVPPYIFYPTTANVLSFF 148
>4Q2R-A nrPDB
Length = 381
Score = 30.6 bits (67), Expect = 0.94, Method: Composition-based stats.
Identities = 13/62 (20%), Positives = 26/62 (41%)
Query: 281 EDFPVLKGNIPVGKPGSGATHNTLGATLDNKKSKKLLGFKFRNLKETIDDTASQILKFEG 340
E FP + + + K G+G + + + LGF L + + D +++ E
Sbjct: 306 EKFPEVLKRLRLQKRGTGGVDTAAVGGVFDVSNADRLGFSEVELVQMVVDGVKLLIEMEQ 365
Query: 341 RI 342
R+
Sbjct: 366 RL 367
>1P33-A nrPDB
Length = 289
Score = 30.6 bits (67), Expect = 0.96, Method: Composition-based stats.
Identities = 16/59 (27%), Positives = 22/59 (37%), Gaps = 2/59 (3%)
Query: 4 FVSGANGFIAQHIVDLLLKEDYKVIGSA-RSQEKAENL-TEAFGNNPKFSMEVVPDISK 60
V+GA + I + L E Y V RS A L P ++ V D+S
Sbjct: 11 LVTGAAKRLGSSIAEALHAEGYTVCLHYHRSAADASTLAATLNARRPNSAITVQADLSN 69
>2EXX-A nrPDB
Length = 306
Score = 30.6 bits (67), Expect = 1.1, Method: Composition-based stats.
Identities = 10/37 (27%), Positives = 15/37 (40%), Gaps = 1/37 (2%)
Query: 3 VFVSGANGFIAQHIVDLLLKED-YKVIGSARSQEKAE 38
V V G G + LL++ +KV R+ K
Sbjct: 14 VVVFGGTGAQGGSVARTLLEDGTFKVRVVTRNPRKKA 50
>2BKA-A nrPDB
Length = 242
Score = 30.3 bits (66), Expect = 1.3, Method: Composition-based stats.
Identities = 19/70 (27%), Positives = 32/70 (45%), Gaps = 4/70 (5%)
Query: 2 SVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKL 61
SVF+ GA+G + ++ +L++ + + K EA+ N + V D KL
Sbjct: 20 SVFILGASGETGRVLLKEILEQGLFSKVTLIGRRKLTFDEEAYKNVNQ----EVVDFEKL 75
Query: 62 DAFDHVFQKH 71
D + FQ H
Sbjct: 76 DDYASAFQGH 85
>5PGZ-A nrPDB
Length = 276
Score = 30.3 bits (66), Expect = 1.4, Method: Composition-based stats.
Identities = 15/66 (22%), Positives = 26/66 (39%)
Query: 3 VFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDISKLD 62
V V+GA+ I + + L K V+ +ARS+E + + S + +
Sbjct: 21 VIVTGASKGIGREMAYHLSKMGAHVVLTARSEEGLQKVVSRCLELGAASAHYIAGTMEDM 80
Query: 63 AFDHVF 68
F F
Sbjct: 81 TFAEQF 86
>6DKT-A nrPDB
Length = 296
Score = 30.3 bits (66), Expect = 1.4, Method: Composition-based stats.
Identities = 11/59 (18%), Positives = 21/59 (35%), Gaps = 9/59 (15%)
Query: 14 QHIVDLLLKEDYKV---------IGSARSQEKAENLTEAFGNNPKFSMEVVPDISKLDA 63
H+++ L Y V ++ E+ +NL N K + +V I +
Sbjct: 31 AHLIERLSDMGYTVEDLGDIPINREKIKNDEELKNLNSVLAGNEKLAQKVNKVIEEKKF 89
>4IQF-A nrPDB
Length = 317
Score = 30.3 bits (66), Expect = 1.4, Method: Composition-based stats.
Identities = 6/33 (18%), Positives = 14/33 (42%)
Query: 16 IVDLLLKEDYKVIGSARSQEKAENLTEAFGNNP 48
++ L+++ Y VIG ++ + P
Sbjct: 19 VLRRLIEDGYDVIGVVTQPDRPVGRKKVLTPTP 51
>1H5Q-A nrPDB
Length = 265
Score = 30.3 bits (66), Expect = 1.4, Method: Composition-based stats.
Identities = 27/140 (19%), Positives = 49/140 (35%), Gaps = 11/140 (7%)
Query: 2 SVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVP-DISK 60
++ V+G N I + V RS A +TE G + D+S
Sbjct: 16 TIIVTGGNRGIGLAFTRAVAAAGANVAVIYRSAADAVEVTEKVGKEFGVKTKAYQCDVSN 75
Query: 61 LDAFDHVFQKHGKD---IKIVLHTA--SPFCFDITDSERDLLIPAVNGVKGILHSIKKYA 115
D Q+ D I ++ A S + D V G+ ++ + A
Sbjct: 76 TDIVTKTIQQIDADLGPISGLIANAGVSVVKPATELTHEDFAFVYDVNVFGVFNTCRAVA 135
Query: 116 ADSVER-----VVLTSSYAA 130
+++ +V+TSS ++
Sbjct: 136 KLWLQKQQKGSIVVTSSMSS 155
>5B1Y-A nrPDB
Length = 270
Score = 29.9 bits (65), Expect = 1.6, Method: Composition-based stats.
Identities = 15/76 (19%), Positives = 32/76 (42%), Gaps = 6/76 (7%)
Query: 4 FVSGANGFIAQHIVDLLLKEDYKVIGSARS----QEKAENLTEAFGNNPKFSMEVVPDIS 59
V+G + I + V +E + V+ + +S EK G+ +++ V D+
Sbjct: 27 LVTGGSRGIGRATVLRFAREGWSVVIAYKSRADLAEKTAEEARRLGSPEAYTVRV--DVG 84
Query: 60 KLDAFDHVFQKHGKDI 75
D+ + + G+ I
Sbjct: 85 DPDSVTEMSSRVGELI 100
>1VIM-A nrPDB
Length = 200
Score = 29.9 bits (65), Expect = 1.6, Method: Composition-based stats.
Identities = 11/29 (37%), Positives = 16/29 (55%), Gaps = 2/29 (6%)
Query: 2 SVFVSGA--NGFIAQHIVDLLLKEDYKVI 28
S+FV GA +G+IA+ L+ Y V
Sbjct: 49 SIFVIGAGRSGYIAKAFAMRLMHLGYTVY 77
>3PVZ-A nrPDB
Length = 399
Score = 29.5 bits (64), Expect = 1.9, Method: Composition-based stats.
Identities = 19/135 (14%), Positives = 41/135 (30%), Gaps = 7/135 (5%)
Query: 2 SVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNPKFSMEVVPDI--- 58
V G G I Q + + K + + + E N+ E + + D
Sbjct: 37 RFLVLGGAGSIGQAVTKEIFKRNPQKLHVVDISEN--NMVELVRDIRSSFGYINGDFQTF 94
Query: 59 -SKLDAFDH-VFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVNGVKGILHSIKKYAA 116
+ + ++ F K VL+ ++ L+ V +I++
Sbjct: 95 ALDIGSIEYDAFIKADGQYDYVLNLSALKHVRSEKDPFTLMRMIDVNVFNTDKTIQQSID 154
Query: 117 DSVERVVLTSSYAAV 131
++ S+ A
Sbjct: 155 AGAKKYFCVSTDKAA 169
>1YXM-A nrPDB
Length = 303
Score = 29.5 bits (64), Expect = 2.0, Method: Composition-based stats.
Identities = 13/45 (28%), Positives = 22/45 (48%), Gaps = 1/45 (2%)
Query: 5 VSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLT-EAFGNNP 48
V+G I + IV LL+ V+ ++R E+ ++ E N P
Sbjct: 23 VTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLP 67
>3V2G-A nrPDB
Length = 271
Score = 29.5 bits (64), Expect = 2.2, Method: Composition-based stats.
Identities = 15/105 (14%), Positives = 37/105 (35%), Gaps = 10/105 (9%)
Query: 2 SVFVSGANGFIAQHIVDLLLKEDYKVIGS-ARSQEKAENLTEAFGNNPKFSMEVVPDISK 60
+ FV+G + I I L E V + + E+A+ + ++ + D
Sbjct: 33 TAFVTGGSRGIGAAIAKRLALEGAAVALTYVNAAERAQAVVSEIEQAGGRAVAIRADNRD 92
Query: 61 LDAFDHVFQKHGKDI---------KIVLHTASPFCFDITDSERDL 96
+A + ++ + + + H+A + D + +
Sbjct: 93 AEAIEQAIRETVEALGGLDILVNSAGIWHSAPLEETTVADFDEVM 137
>4AXH-A nrPDB
Length = 668
Score = 29.5 bits (64), Expect = 2.3, Method: Composition-based stats.
Identities = 20/109 (18%), Positives = 36/109 (33%), Gaps = 6/109 (5%)
Query: 150 NPATWESCQSDPVNAYCGSKKFAE-KAAWEFLEENRDSVKFELTAVNPVYVFGPQMFDK- 207
+ +E+ + + + G K AE + W+ + K VNP Q+ +
Sbjct: 56 DREEFEAAKRGLIAPFSGQIKNAEGQVVWDMGAYQFLNDKDAADTVNPSLWRQAQLNNIA 115
Query: 208 ---DVKKHLNTSCELVNSLMHLSPEDKIPELFGGYIDVRDVAKAHLVAF 253
+V L L + M + D L A+A L +
Sbjct: 116 GLFEVMPKLYQVRGLDPANMTIIEGDSGLVLIDTLTTAE-TARAALDLY 163
>2WEK-A nrPDB
Length = 341
Score = 29.5 bits (64), Expect = 2.3, Method: Composition-based stats.
Identities = 19/66 (28%), Positives = 28/66 (42%), Gaps = 1/66 (1%)
Query: 3 VFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEAFGNNP-KFSMEVVPDISKL 61
V V+ A G Q + L K VIG+ S EK+ L + P + E V + K
Sbjct: 146 VLVTAAAGGTGQFAMQLSKKAKCHVIGTCSSDEKSAFLKSLGCDRPINYKTEPVGTVLKQ 205
Query: 62 DAFDHV 67
+ + V
Sbjct: 206 EYPEGV 211
>2TMD-A nrPDB
Length = 729
Score = 29.5 bits (64), Expect = 2.4, Method: Composition-based stats.
Identities = 9/42 (21%), Positives = 19/42 (45%), Gaps = 1/42 (2%)
Query: 2 SVFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLTEA 43
SV + GA G +L++ Y V + +++ +L +
Sbjct: 391 SVLIVGA-GPSGSEAARVLMESGYTVHLTDTAEKIGGHLNQV 431
>5ZG8-A nrPDB
Length = 438
Score = 28.7 bits (62), Expect = 3.6, Method: Composition-based stats.
Identities = 17/110 (15%), Positives = 31/110 (28%), Gaps = 4/110 (3%)
Query: 47 NPKFSMEVVPDISKLDAFDHVFQKHGKDIKIVLHTASPFCFDITDSERDLLIPAVN-GVK 105
+ S E+ A + + H + A D E L + G
Sbjct: 252 LERRSRELEMLGRDPKALEPAAEGHYPRLTYKEAVALVNRIAQEDPEVPPLPYGEDFGAP 311
Query: 106 GILHSIKKYAAD-SVERVVLTSSYAAVFDMAKENDKSLTFNEESWNPATW 154
+++ VER + A + D L N++ P +
Sbjct: 312 HEAALSRRFDRPVFVER--YPARIKAFYMEPDPEDPELVLNDDLLAPEGY 359
>3PVW-A nrPDB
Length = 695
Score = 28.3 bits (61), Expect = 4.5, Method: Composition-based stats.
Identities = 18/74 (24%), Positives = 28/74 (37%), Gaps = 13/74 (17%)
Query: 230 DKIPELFGGYIDVRDVAKAH-------------LVAFQKRETIGQRLIVSEARFTMQDVL 276
+KI GY+ RD H + ++K ET +RL+ S F +
Sbjct: 56 EKIFSQKLGYLLFRDFCLKHLEEAKPLVEFYEEIKKYEKLETEEERLVCSREIFDTYIMK 115
Query: 277 DILNEDFPVLKGNI 290
++L P K I
Sbjct: 116 ELLACSHPFSKSAI 129
>4HP8-A nrPDB
Length = 247
Score = 27.6 bits (59), Expect = 9.1, Method: Composition-based stats.
Identities = 20/99 (20%), Positives = 38/99 (38%), Gaps = 8/99 (8%)
Query: 4 FVSGANGFIAQHIVDLLLKEDYKVI-GSARSQEKAENLTEAFGNNPKFSMEVVPDISKLD 62
V+GAN + Q I L +V+ + R+ ++ ++ G N + ++ D +
Sbjct: 13 LVTGANTGLGQAIAVGLAAAGAEVVCAARRAPDETLDIIAKDGGN---ASALLIDFADPL 69
Query: 63 AFDHVFQKHGKDI----KIVLHTASPFCFDITDSERDLL 97
A F G DI ++ A F D + +
Sbjct: 70 AAKDSFTDAGFDILVNNAGIIRRADSVEFSELDWDEVMD 108
Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta
Posted date: Jan 3, 2023 9:05 PM
Number of letters in database: 10,336,785
Number of sequences in database: 36,641
Lambda K H
0.308 0.115 0.274
Lambda K H
0.267 0.0357 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,545,476
Number of Sequences: 36641
Number of extensions: 372564
Number of successful extensions: 1495
Number of sequences better than 10.0: 138
Number of HSP's better than 10.0 without gapping: 102
Number of HSP's successfully gapped in prelim test: 74
Number of HSP's that attempted gapping in prelim test: 1253
Number of HSP's gapped (non-prelim): 180
length of query: 342
length of database: 10,336,785
effective HSP length: 98
effective length of query: 244
effective length of database: 6,745,967
effective search space: 1646015948
effective search space used: 1646015948
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.3 bits)
S2: 59 (27.5 bits)