BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q10471 (571 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 5AJO-A nrPDB 1192 0.0 5NQA-A nrPDB 375 e-104 2D7R-A nrPDB 346 2e-95 6IWR-A nrPDB 322 3e-88 3RTJ-B nrPDB 45 1e-04 1RZO-B nrPDB 42 7e-04 1ABR-B nrPDB 42 0.001 6HNQ-B nrPDB 41 0.002 3A22-A nrPDB 40 0.004 2Q3N-B nrPDB 39 0.005 2Z49-A nrPDB 36 0.055 5MLZ-A nrPDB 35 0.097 3D7W-B nrPDB 35 0.10 2MLL-B nrPDB 34 0.21 1YF8-B nrPDB 33 0.23 5Y97-C nrPDB 32 0.53 1HWM-B nrPDB 32 0.62 4ZFY-B nrPDB 30 3.4 1SMV-A nrPDB 30 3.7 2VLC-A nrPDB 30 4.1 5IW7-A nrPDB 29 5.9 6E31-A nrPDB 28 7.6 1IT0-A nrPDB 28 7.7 3CAH-A nrPDB 28 8.1 3TCA-A nrPDB 28 8.3 >5AJO-A nrPDB Length = 571 Score = 1192 bits (3083), Expect = 0.0, Method: Compositional matrix adjust. Identities = 570/571 (99%), Positives = 571/571 (100%) Query: 1 MRRRSRMLLCFAFLWVLGIAYYMYSGGGSALAGGAGGGAGRKEDWNEIDPIKKKDLHHSN 60 MRRRSRMLLCFAFLWVLGIAYYMYSGGGSALAGGAGGGAGRKEDWNEIDPIKKKDLHHSN Sbjct: 1 MRRRSRMLLCFAFLWVLGIAYYMYSGGGSALAGGAGGGAGRKEDWNEIDPIKKKDLHHSN 60 Query: 61 GEEKAQSMETLPPGKVRWPDFNQEAYVGGTMVRSGQDPYARNKFNQVESDKLRMDRAIPD 120 GEEKAQSMETLPPGKVRWPDFNQEAYVGGTMVRSGQDPYARNKFNQVESDKLRMDRAIPD Sbjct: 61 GEEKAQSMETLPPGKVRWPDFNQEAYVGGTMVRSGQDPYARNKFNQVESDKLRMDRAIPD 120 Query: 121 TRHDQCQRKQWRVDLPATSVVITFHNEARSALLRTVVSVLKKSPPHLIKEIILVDDYSND 180 TRHDQCQRKQWRVDLPATSVVITFHNEARSALLRTVVSVLKKSPPHLIKEIILVDDYSND Sbjct: 121 TRHDQCQRKQWRVDLPATSVVITFHNEARSALLRTVVSVLKKSPPHLIKEIILVDDYSND 180 Query: 181 PEDGALLGKIEKVRVLRNDRREGLMRSRVRGADAAQAKVLTFLDSHCECNEHWLEPLLER 240 PEDGALLGKIEKVRVLRNDRREGLMRSRVRGADAAQAKVLTFLDSHCECNEHWLEPLLER Sbjct: 181 PEDGALLGKIEKVRVLRNDRREGLMRSRVRGADAAQAKVLTFLDSHCECNEHWLEPLLER 240 Query: 241 VAEDRTRVVSPIIDVINMDNFQYVGASADLKGGFDWNLVFKWDYMTPEQRRSRQGNPVAP 300 VAEDRTRVVSPIIDVINMDNFQYVGASADLKGGFDWNLVFKWDYMTPEQRRSRQGNPVAP Sbjct: 241 VAEDRTRVVSPIIDVINMDNFQYVGASADLKGGFDWNLVFKWDYMTPEQRRSRQGNPVAP 300 Query: 301 IKTPMIAGGLFVMDKFYFEELGKYDMMMDVWGGENLEISFRVWQCGGSLEIIPCSRVGHV 360 IKTPMIAGGLFVMDKFYFEELGKYDMMMDVWGGENLEISFRVWQCGGSLEIIPCSRVGHV Sbjct: 301 IKTPMIAGGLFVMDKFYFEELGKYDMMMDVWGGENLEISFRVWQCGGSLEIIPCSRVGHV 360 Query: 361 FRKQHPYTFPGGSGTVFARNTRRAAEVWMDEYKNFYYAAVPSARNVPYGNIQSRLELRKK 420 FRKQHPYTFPGGSGTVFARNTRRAAEVWMDEYKNFYYAAVPSARNVPYGNIQSRLELRKK Sbjct: 361 FRKQHPYTFPGGSGTVFARNTRRAAEVWMDEYKNFYYAAVPSARNVPYGNIQSRLELRKK 420 Query: 421 LSCKPFKWYLENVYPELRVPDHQDIAFGALQQGTNCLDTLGHFADGVVGVYECHNAGGNQ 480 LSCKPFKWYLENVYPELRVPDHQDIAFGALQQGTNCLDTLGHFADGVVGVYECHNAGGNQ Sbjct: 421 LSCKPFKWYLENVYPELRVPDHQDIAFGALQQGTNCLDTLGHFADGVVGVYECHNAGGNQ 480 Query: 481 EWALTKEKSVKHMDLCLTVVDRAPGSLIKLQGCRENDSRQKWEQIEGNSKLRHVGSNLCL 540 EWALTKEKSVKHMDLCLTVVDRAPGSLIKLQGCRE+DSRQKWEQIEGNSKLRHVGSNLCL Sbjct: 481 EWALTKEKSVKHMDLCLTVVDRAPGSLIKLQGCREDDSRQKWEQIEGNSKLRHVGSNLCL 540 Query: 541 DSRTAKSGGLSVEVCGPALSQQWKFTLNLQQ 571 DSRTAKSGGLSVEVCGPALSQQWKFTLNLQQ Sbjct: 541 DSRTAKSGGLSVEVCGPALSQQWKFTLNLQQ 571 >5NQA-A nrPDB Length = 578 Score = 375 bits (962), Expect = e-104, Method: Compositional matrix adjust. Identities = 224/574 (39%), Positives = 321/574 (55%), Gaps = 44/574 (7%) Query: 4 RSRMLLCFAFLWVLGIAYYMYSGGGSALAGGAGGGAGRKEDWNEIDPIKKKDLHHSNGEE 63 +S +LL F L +AY S AG G R E+ + DL N E+ Sbjct: 10 KSCLLLAF-----LTVAYIFVELLVSTFHASAGAGRAR-----ELGSRRLSDLQ-KNTED 58 Query: 64 KAQSMETLPPGKVR----WPDFNQEAYVGGTMVRSGQDPYARNKFNQVESDKLRMDRAIP 119 ++ + PP R W ++ + ++ ++ R N SD++ + R I Sbjct: 59 LSRPLYKKPPADSRALGEWGKASK-LQLNEDELKQQEELIERYAINIYLSDRISLHRHIE 117 Query: 120 DTRHDQCQRKQWRV-DLPATSVVITFHNEARSALLRTVVSVLKKSPPHLIKEIILVDDYS 178 D R +C+ +++ LP TSV+I F+NEA S LLRT+ SVL+ SP L+KEIILVDD S Sbjct: 118 DKRMYECKSQKFNYRTLPTTSVIIAFYNEAWSTLLRTIHSVLETSPAVLLKEIILVDDLS 177 Query: 179 N----DPEDGALLGKIEKVRVLRNDRREGLMRSRVRGADAAQAKVLTFLDSHCECNEHWL 234 + + + +++VR++R ++REGL+R+R+ GA A VLTFLD HCECN WL Sbjct: 178 DRVYLKTQLETYISNLDRVRLIRTNKREGLVRARLIGATFATGDVLTFLDCHCECNSGWL 237 Query: 235 EPLLERVAEDRTRVVSPIIDVINMDNFQ-YVGASADLKGGFDWNLVFKWDYMTPEQRRSR 293 EPLLER+ D T VV P+ID I+ + F+ Y+ + GGFDW L F+W + P+Q R R Sbjct: 238 EPLLERIGRDETAVVCPVIDTIDWNTFEFYMQIGEPMIGGFDWRLTFQW-HSVPKQERDR 296 Query: 294 QGNPVAPIKTPMIAGGLFVMDKFYFEELGKYDMMMDVWGGENLEISFRVWQCGGSLEIIP 353 + + + PI++P +AGGLF + K YF+ LG YD M+VWGGENLE+SFRVWQCGG LEI P Sbjct: 297 RISRIDPIRSPTMAGGLFAVSKKYFQYLGTYDTGMEVWGGENLELSFRVWQCGGKLEIHP 356 Query: 354 CSRVGHVFRKQHPYTFPGGSGTVFARNTRRAAEVWMDEYKNFYYAAVPSARNVPYGNIQS 413 CS VGHVF K+ PY P F +NT RAAEVWMDEYK +Y P AR YG+I Sbjct: 357 CSHVGHVFPKRAPYARPN-----FLQNTARAAEVWMDEYKEHFYNRNPPARKEAYGDISE 411 Query: 414 RLELRKKLSCKPFKWYLENVYPELRVPDHQDIAFGALQQ---GTNCLDTLG---HFADGV 467 R LR++L CK F WYL+NV+P L VP+ + GA++ + CLD + Sbjct: 412 RKLLRERLRCKSFDWYLKNVFPNLHVPEDRPGWHGAIRSRGISSECLDYNSPDNNPTGAN 471 Query: 468 VGVYECHNAGGNQEWALTKEKSVKH---MDLCLTVVDRAPGSLIKLQGCREN----DSRQ 520 + ++ CH GGNQ + T K ++ +LC V ++ + + +Q C ++ + Sbjct: 472 LSLFGCHGQGGNQFFEYTSNKEIRFNSVTELCAEVPEQK--NYVGMQNCPKDGFPVPANI 529 Query: 521 KWEQIEGNSKLRHVGSNLCLDSRTAKSGGLSVEV 554 W + + + H S LCL + G V++ Sbjct: 530 IW-HFKEDGTIFHPHSGLCLSAYRTPEGRPDVQM 562 >2D7R-A nrPDB Length = 570 Score = 346 bits (887), Expect = 2e-95, Method: Compositional matrix adjust. Identities = 209/582 (35%), Positives = 307/582 (52%), Gaps = 76/582 (13%) Query: 26 GGGSALAGGAGGGAGRKE-------------DWNEIDPIKKKDLHHSNGEEKAQSMETLP 72 G G+A+A AG G+ ++ DW++ + I++ NGE+ Sbjct: 9 GSGAAVAPAAGQGSHSRQKKTFFLGDGQKLKDWHDKEAIRRDAQRVGNGEQG-------- 60 Query: 73 PGKVRWPDFNQEAYVGGTMVRSGQDPYARNKFNQVESDKLRMDRAIPDTRHDQCQRKQWR 132 Y R Q Y N FN SDK+ ++R++PD RH C K++ Sbjct: 61 -----------RPYPMTDAERVDQ-AYRENGFNIYVSDKISLNRSLPDIRHPNCNSKRYL 108 Query: 133 VDLPATSVVITFHNEARSALLRTVVSVLKKSPPHLIKEIILVDDYSNDP------EDGAL 186 LP TS++I FHNE S+LLRTV SVL +SPP L+ EI+LVDD+S+ ED Sbjct: 109 ETLPNTSIIIPFHNEGWSSLLRTVHSVLNRSPPELVAEIVLVDDFSDREHLKKPLED--Y 166 Query: 187 LGKIEKVRVLRNDRREGLMRSRVRGADAAQAKVLTFLDSHCECNEHWLEPLLERVAEDRT 246 + VR+LR +REGL+R+R+ GA A V+TFLDSHCE N +WL PLL+R+A +R Sbjct: 167 MALFPSVRILRTKKREGLIRTRMLGASVATGDVITFLDSHCEANVNWLPPLLDRIARNRK 226 Query: 247 RVVSPIIDVINMDNFQYVGASAD-LKGGFDWNLVFKWDYMTPEQRRSRQGNPVAPIKTPM 305 +V P+IDVI+ D+F+Y + D ++G FDW + +K + PE +++ +P P ++P+ Sbjct: 227 TIVCPMIDVIDHDDFRYETQAGDAMRGAFDWEMYYKRIPIPPELQKA---DPSDPFESPV 283 Query: 306 IAGGLFVMDKFYFEELGKYDMMMDVWGGENLEISFRVWQCGGSLEIIPCSRVGHVFRKQH 365 +AGGLF +D+ +F ELG YD +++WGGE EISF+VW CGG +E IPCSRVGH++RK Sbjct: 284 MAGGLFAVDRKWFWELGGYDPGLEIWGGEQYEISFKVWMCGGRMEDIPCSRVGHIYRKYV 343 Query: 366 PYTFPGGSGTVFARNTRRAAEVWMDEYKNFYYAAVPSARNVPYGNIQSRLELRKKLSCKP 425 PY P +G ARN +R AEVWMDEY + Y P R++ G++ + +LR L+CK Sbjct: 344 PYKVP--AGVSLARNLKRVAEVWMDEYAEYIYQRRPEYRHLSAGDVAVQKKLRSSLNCKS 401 Query: 426 FKWYLENV-------YPELRVPDHQDIAFGALQQ-GTN-CLDTLGHFADGVVGVYECHNA 476 FKW++ + YP + P A+G ++ GT C DT + + C Sbjct: 402 FKWFMTKIAWDLPKFYPPVEPP---AAAWGEIRNVGTGLCADTKHGALGSPLRLEGCVRG 458 Query: 477 GGNQEW------ALTKEKSVKHMD------LCLTVVDRAPGSLIKLQGCRENDSRQKWEQ 524 G W T + ++ D C + S + L C Q W + Sbjct: 459 RGEAAWNNMQVFTFTWREDIRPGDPQHTKKFCFDAISHT--SPVTLYDCHSMKGNQLW-K 515 Query: 525 IEGNSKLRHVGSNLCLDSRTAKSGGLSVEVCGP-ALSQQWKF 565 + L H S C+D + + + C P +L+QQW F Sbjct: 516 YRKDKTLYHPVSGSCMDC-SESDHRIFMNTCNPSSLTQQWLF 556 >6IWR-A nrPDB Length = 597 Score = 322 bits (825), Expect = 3e-88, Method: Compositional matrix adjust. Identities = 178/496 (35%), Positives = 289/496 (58%), Gaps = 30/496 (6%) Query: 69 ETLPPGKVRWPDFNQEAYVGGTMVRSG-QDPYARNKFNQVESDKLRMDRAIPDTRHDQCQ 127 E PPG V P + V G + Q FN V SD + +DR++ D R ++C+ Sbjct: 79 EPEPPGVVGGPGEKAKPLVLGPEFKQAIQASIKEFGFNMVASDMISLDRSVNDLRQEECK 138 Query: 128 RKQWRVDLPATSVVITFHNEARSALLRTVVSVLKKSPPHLIKEIILVDDYSNDPEDGALL 187 + +L +SVVI FHNE S L+RTV SV+K++P + EI+L+DD+SN L Sbjct: 139 YWHYDENLLTSSVVIVFHNEGWSTLMRTVHSVIKRTPRKYLAEIVLIDDFSNKEHLKEKL 198 Query: 188 GKIEK-----VRVLRNDRREGLMRSRVRGADAAQ-AKVLTFLDSHCECNEHWLEPLLERV 241 + K V+V RN+RREGL+++R GA A+ +VL +LD+HCE +W PL+ + Sbjct: 199 DEYIKLWNGLVKVFRNERREGLIQARSIGAQKAKLGQVLIYLDAHCEVAVNWYAPLVAPI 258 Query: 242 AEDRTRVVSPIIDVINMDNFQYV---GASAD--LKGGFDWNLVFKWDYMTPEQRRSRQGN 296 ++DRT P+IDVIN + ++ + G D +G +DW++++K +TP+++R R+ Sbjct: 259 SKDRTICTVPLIDVINGNTYEIIPQGGGDEDGYARGAWDWSMLWKRVPLTPQEKRLRKTK 318 Query: 297 PVAPIKTPMIAGGLFVMDKFYFEELGKYDMMMDVWGGENLEISFRVWQCGGSLEIIPCSR 356 P ++P +AGGLF +++ +F ELG YD + +WGGEN EIS+++WQCGG L +PCSR Sbjct: 319 -TEPYRSPAMAGGLFAIEREFFFELGLYDPGLQIWGGENFEISYKIWQCGGKLLFVPCSR 377 Query: 357 VGHVFRKQ-----HPYTFPGGSGTVFARNTRRAAEVWMDEYKNFYYAAVPSARNVPYGNI 411 VGH++R + P + G S T+ +N R EVW DEYK+++YA+ P ++ +PYG+I Sbjct: 378 VGHIYRLEGWQGNPPPIYVGSSPTL--KNYVRVVEVWWDEYKDYFYASRPESQALPYGDI 435 Query: 412 QSRLELRKKLSCKPFKWYLENVYPELR----VPDHQDIAFGALQ--QGTNCLDTLGHFAD 465 + R+ +CK FKW++E + ++ +P +++ +G ++ + C+D++G Sbjct: 436 SELKKFREDHNCKSFKWFMEEIAYDITSHYPLPP-KNVDWGEIRGFETAYCIDSMGKTNG 494 Query: 466 GVVGVYECHNAGGNQEWALTKEKSVKHMDLCLTVVDRAPGSLIKLQGCRENDSRQKWEQI 525 G V + CH GGNQ + + + + D CLT A GS + + C N+ ++ W+ Sbjct: 495 GFVELGPCHRMGGNQLFRINEANQLMQYDQCLT--KGADGSKVMITHCNLNEFKE-WQYF 551 Query: 526 EGNSKLRHVGSNLCLD 541 + + H+ S CLD Sbjct: 552 KNLHRFTHIPSGKCLD 567 >3RTJ-B nrPDB Length = 262 Score = 45.1 bits (105), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 34/119 (28%), Positives = 56/119 (47%), Gaps = 4/119 (3%) Query: 456 CLDTL-GHFADG-VVGVYEC-HNAGGNQEWALTKEKSVKHMDLCLTVVDRAPGSLIKLQG 512 C+D G F +G + ++ C N NQ W L ++ +++ CLT +PG + + Sbjct: 20 CVDVRDGRFHNGNAIQLWPCKSNTDANQLWTLKRDNTIRSNGKCLTTYGYSPGVYVMIYD 79 Query: 513 CRENDSRQKWEQIEGNSKLRHVGSNLCLDSRTAKSG-GLSVEVCGPALSQQWKFTLNLQ 570 C + QI N + + S+L L + + SG L+V+ A+SQ W T N Q Sbjct: 80 CNTAATDATRWQIWDNGTIINPRSSLVLAATSGNSGTTLTVQTNIYAVSQGWLPTNNTQ 138 Score = 35.4 bits (80), Expect = 0.072, Method: Compositional matrix adjust. Identities = 22/83 (26%), Positives = 41/83 (49%), Gaps = 4/83 (4%) Query: 466 GVVGVYECHNAGGNQEWALTKEKSVK---HMDLCLTVVDRAPGSLIKLQGCRENDSRQKW 522 G V + +C + Q+WAL + S++ + D CLT +++K+ C S Q+W Sbjct: 157 GQVWIEDCSSEKAEQQWALYADGSIRPQQNRDNCLTSDSNIRETVVKILSCGPASSGQRW 216 Query: 523 EQIEGNSKLRHVGSNLCLDSRTA 545 + + + ++ S L LD R + Sbjct: 217 -MFKNDGTILNLYSGLVLDVRAS 238 >1RZO-B nrPDB Length = 262 Score = 42.0 bits (97), Expect = 7e-04, Method: Compositional matrix adjust. Identities = 35/119 (29%), Positives = 54/119 (45%), Gaps = 4/119 (3%) Query: 456 CLDTLGH-FADG-VVGVYEC-HNAGGNQEWALTKEKSVKHMDLCLTVVDRAPGSLIKLQG 512 C+D G F DG + ++ C N NQ W L K+ +++ CLT+ +P + + Sbjct: 20 CVDVTGEEFFDGNPIQLWPCKSNTDWNQLWTLRKDSTIRSNGKCLTISKSSPRQQVVIYN 79 Query: 513 CRENDSRQKWEQIEGNSKLRHVGSNLCLDSRTAKSGG-LSVEVCGPALSQQWKFTLNLQ 570 C QI N + + S L L + + SG L+V+ A+SQ W T N Q Sbjct: 80 CSTATVGATRWQIWDNRTIINPRSGLVLAATSGNSGTKLTVQTNIYAVSQGWLPTNNTQ 138 Score = 36.2 bits (82), Expect = 0.037, Method: Compositional matrix adjust. Identities = 22/81 (27%), Positives = 41/81 (50%), Gaps = 4/81 (4%) Query: 466 GVVGVYECHNAGGNQEWALTKEKSVK---HMDLCLTVVDRAPGSLIKLQGCRENDSRQKW 522 G V + +C + Q+WAL + S++ + D CLT G+++K+ C S Q+W Sbjct: 157 GKVWLEDCTSEKAEQQWALYADGSIRPQQNRDNCLTTDANIKGTVVKILSCGPASSGQRW 216 Query: 523 EQIEGNSKLRHVGSNLCLDSR 543 + + + ++ + L LD R Sbjct: 217 -MFKNDGTILNLYNGLVLDVR 236 >1ABR-B nrPDB Length = 267 Score = 41.6 bits (96), Expect = 0.001, Method: Compositional matrix adjust. Identities = 24/87 (27%), Positives = 42/87 (48%), Gaps = 1/87 (1%) Query: 479 NQEWALTKEKSVKHMDLCLTVVDRAPGSLIKLQGCRENDSRQKWEQIEGNSKLRHVGSNL 538 NQ W L +K+++ CLT APGS + + C + + +I N + + S L Sbjct: 51 NQLWTLKSDKTIRSNGKCLTTYGYAPGSYVMIYDCTSAVAEATYWEIWDNGTIINPKSAL 110 Query: 539 CLDSRTAKSGG-LSVEVCGPALSQQWK 564 L + ++ GG L+V+ + Q W+ Sbjct: 111 VLSAESSSMGGTLTVQTNEYLMRQGWR 137 Score = 37.0 bits (84), Expect = 0.021, Method: Compositional matrix adjust. Identities = 20/58 (34%), Positives = 31/58 (53%), Gaps = 3/58 (5%) Query: 468 VGVYECHNAGGNQEWALTKE---KSVKHMDLCLTVVDRAPGSLIKLQGCRENDSRQKW 522 V + +C + Q+WAL + +SV++ + CLT D GS I L GC + Q+W Sbjct: 164 VWMADCDSNKKEQQWALYTDGSIRSVQNTNNCLTSKDHKQGSTILLMGCSNGWASQRW 221 Score = 29.3 bits (64), Expect = 4.5, Method: Compositional matrix adjust. Identities = 22/76 (28%), Positives = 32/76 (42%), Gaps = 6/76 (7%) Query: 492 HMDLCLTVVDRAPGSLIKLQGCRENDSRQKWEQIEGNSKLRHVGSNLCLDSRTAKSGG-- 549 + DLC+ +A GS + + C N Q+W S +N CL S+ K G Sbjct: 152 YSDLCM----QAQGSNVWMADCDSNKKEQQWALYTDGSIRSVQNTNNCLTSKDHKQGSTI 207 Query: 550 LSVEVCGPALSQQWKF 565 L + SQ+W F Sbjct: 208 LLMGCSNGWASQRWVF 223 >6HNQ-B nrPDB Length = 345 Score = 40.8 bits (94), Expect = 0.002, Method: Compositional matrix adjust. Identities = 38/126 (30%), Positives = 65/126 (51%), Gaps = 14/126 (11%) Query: 132 RVDLPATSVVI-TFHNEARSALLRTVVSVLKKSPPHLIKEIILVDDYSNDPEDGALLGKI 190 R + SV++ TF+N + L RT+ SVL ++ E+I++DD+SND +G L I Sbjct: 16 RGSMKKVSVIMPTFNNGEK--LHRTISSVLNQTMKSTDYELIIIDDHSND--NGETLNVI 71 Query: 191 EKVRVLRNDRREGLMRS-------RVRGADAAQAKVLTFLDSHCECNEHWLEPLLERVAE 243 +K + L R + L ++ R G ++A+ + FLDS +E LE L E Sbjct: 72 KKYKGLV--RFKQLKKNSGNASVPRNTGLKMSKAEYVFFLDSDDLLHERALEDLYNYGKE 129 Query: 244 DRTRVV 249 + + ++ Sbjct: 130 NNSDLI 135 >3A22-A nrPDB Length = 614 Score = 39.7 bits (91), Expect = 0.004, Method: Compositional matrix adjust. Identities = 30/103 (29%), Positives = 48/103 (46%), Gaps = 9/103 (8%) Query: 470 VYECHNAGGNQEWALTKEKS-VKHMDLCLTVVDRAP--GSLIKLQGCRENDSRQKWEQIE 526 +++C N G NQ W T K V + + CL + G+ + + C + QKW I Sbjct: 515 LWDC-NGGPNQSWTYTSRKELVLYGNKCLDAYNLGTTNGTKVVIWDC-NGQANQKWN-IN 571 Query: 527 GNSKLRHVGSNLCLD---SRTAKSGGLSVEVCGPALSQQWKFT 566 + + +V + LCLD + TA L + CG +Q+W T Sbjct: 572 SDGTITNVNAGLCLDAYNAATANGTSLVLWSCGTGDNQKWTVT 614 >2Q3N-B nrPDB Length = 267 Score = 39.3 bits (90), Expect = 0.005, Method: Compositional matrix adjust. Identities = 23/87 (26%), Positives = 41/87 (47%), Gaps = 1/87 (1%) Query: 479 NQEWALTKEKSVKHMDLCLTVVDRAPGSLIKLQGCRENDSRQKWEQIEGNSKLRHVGSNL 538 NQ W L +K+++ CLT APG+ + + C + + I N + + S L Sbjct: 51 NQLWTLKSDKTIRSKGKCLTTYGYAPGNYVMIYDCSSAVAEATYWDIWDNGTIINPKSGL 110 Query: 539 CLDSRTAKSGG-LSVEVCGPALSQQWK 564 L + ++ GG L+V+ + Q W+ Sbjct: 111 VLSAESSSMGGTLTVQKNDYRMRQGWR 137 Score = 31.6 bits (70), Expect = 0.91, Method: Compositional matrix adjust. Identities = 30/141 (21%), Positives = 59/141 (41%), Gaps = 30/141 (21%) Query: 450 LQQGTNCLDTLGHFADGVVGVYE-CHNAGGNQEWA----LTKE------------KSVKH 492 ++QG + F + G ++ C A GN W +TKE + V++ Sbjct: 132 MRQGWRTGNDTSPFVTSIAGFFKLCMEAHGNSMWLDVCDITKEEQQWAVYPDGSIRPVQN 191 Query: 493 MDLCLTVVDRAPGSLIKLQGCRENDSRQKWEQIEGNSKLRHVGSNLCLDSRTAKSGGLSV 552 + CLT + G+ I + GC + Q+W + + + ++ ++ +D +++ Sbjct: 192 TNNCLTCEEHKQGATIVMMGCSNAWASQRW-VFKSDGTIYNLYDDMVMDVKSSD------ 244 Query: 553 EVCGPALSQ--QWKFTLNLQQ 571 P+L Q W +T N Q Sbjct: 245 ----PSLKQIILWPYTGNANQ 261 >2Z49-A nrPDB Length = 432 Score = 35.8 bits (81), Expect = 0.055, Method: Compositional matrix adjust. Identities = 28/117 (23%), Positives = 47/117 (40%), Gaps = 10/117 (8%) Query: 456 CLDTLGHFADGVVGVYECHNAGGNQEWALTKEKSV-------KHMDLCLTVVDRAPGSLI 508 CLD G G +GVY+C N + ++ + + DLCL V + Sbjct: 119 CLDIEGSDGTGDIGVYDCQNLDDQYFYVRSRGPELFYGRLRNEKSDLCLDVEGSDGKGNV 178 Query: 509 KLQGCRENDSRQKWEQIEGNSKLRHVGSNLCLDSRTAK-SGGLSVEVCGPALSQQWK 564 + C +N +W + N ++ + S +CLD + SG + + C Q W Sbjct: 179 LMYSCEDN--LDQWFRYYENGEIVNAKSGMCLDVEGSDGSGNVGIYRCDDLRDQMWS 233 >5MLZ-A nrPDB Length = 374 Score = 35.0 bits (79), Expect = 0.097, Method: Compositional matrix adjust. Identities = 29/106 (27%), Positives = 49/106 (46%), Gaps = 4/106 (3%) Query: 138 TSVVITFHNEARSALLRTVVSVLKKSPPHLIKEIILVDDYSNDP--EDGALLGKIEKVRV 195 SV+I +NE + L + S + + L EI++VDD S D E L V+V Sbjct: 25 VSVIIPTYNEREN--LEELFSRIDNALQGLNYEIVVVDDDSPDRTWEKAQELSSKYPVKV 82 Query: 196 LRNDRREGLMRSRVRGADAAQAKVLTFLDSHCECNEHWLEPLLERV 241 +R + +GL + +RG A V +D+ + + L+E + Sbjct: 83 IRRTKEKGLSSAVIRGFKEASGDVFVVMDADLQHPPEVIPKLIEAI 128 >3D7W-B nrPDB Length = 265 Score = 34.7 bits (78), Expect = 0.10, Method: Compositional matrix adjust. Identities = 23/86 (26%), Positives = 36/86 (41%), Gaps = 1/86 (1%) Query: 479 NQEWALTKEKSVKHMDLCLTVVDRAPGSLIKLQGCRENDSRQKWEQIEGNSKLRHVGSNL 538 NQ W + K+ +++ CLT G + + C QI GN + + SNL Sbjct: 47 NQLWTIKKDGTIRSNGSCLTTYGYTAGVYVMIFDCNTAVREATIWQIWGNGTIINPRSNL 106 Query: 539 CLDSRTAKSG-GLSVEVCGPALSQQW 563 L + + G L+V+ L Q W Sbjct: 107 VLAASSGIKGTTLTVQTLDYTLGQGW 132 Score = 32.3 bits (72), Expect = 0.63, Method: Compositional matrix adjust. Identities = 21/70 (30%), Positives = 32/70 (45%), Gaps = 7/70 (10%) Query: 456 CLDTLGHFADGVVGVYECHNAGGNQEWALTKEKSVKHMDL---CLTVVDRAPGSLIKLQG 512 C+++ G G V V C NQ WAL + S++ L CLT + ++I + Sbjct: 152 CMESAG----GSVYVETCTAGQENQRWALYGDGSIRPKQLQSQCLTNGRDSISTVINIVS 207 Query: 513 CRENDSRQKW 522 C S Q+W Sbjct: 208 CSAGSSGQRW 217 >2MLL-B nrPDB Length = 255 Score = 33.9 bits (76), Expect = 0.21, Method: Compositional matrix adjust. Identities = 22/86 (25%), Positives = 36/86 (41%), Gaps = 1/86 (1%) Query: 479 NQEWALTKEKSVKHMDLCLTVVDRAPGSLIKLQGCRENDSRQKWEQIEGNSKLRHVGSNL 538 NQ W + ++ +++ CLT G + + C QI GN + + SNL Sbjct: 43 NQLWTIKRDGTIRSNGSCLTTYGYTAGVYVMIFDCATAVGEATVWQIWGNGTIINPRSNL 102 Query: 539 CLDSRTAKSG-GLSVEVCGPALSQQW 563 L + + G L+V+ L Q W Sbjct: 103 VLAASSGIKGTTLTVQTLDYTLGQGW 128 >1YF8-B nrPDB Length = 255 Score = 33.5 bits (75), Expect = 0.23, Method: Compositional matrix adjust. Identities = 22/86 (25%), Positives = 36/86 (41%), Gaps = 1/86 (1%) Query: 479 NQEWALTKEKSVKHMDLCLTVVDRAPGSLIKLQGCRENDSRQKWEQIEGNSKLRHVGSNL 538 NQ W + ++ +++ CLT G + + C QI GN + + SNL Sbjct: 43 NQLWTIKRDGTIRSNGSCLTTYGYTAGVYVMIFDCNTAVREATIWQIWGNGTIINPRSNL 102 Query: 539 CLDSRTAKSG-GLSVEVCGPALSQQW 563 L + + G L+V+ L Q W Sbjct: 103 ALAASSGIKGTTLTVQTLDYTLGQGW 128 >5Y97-C nrPDB Length = 264 Score = 32.3 bits (72), Expect = 0.53, Method: Compositional matrix adjust. Identities = 29/114 (25%), Positives = 53/114 (46%), Gaps = 5/114 (4%) Query: 456 CLDTLGHF-ADGV-VGVYECHNAGGNQEWALTKEKSVKHMDLCLTVVDRAPGSLIKLQGC 513 C+D G +DG + +Y C NQ+W + +V+ + CL + G+L+ + C Sbjct: 19 CVDVAGALTSDGSRLILYPCGQQV-NQKWTFHSDGTVRSLGKCLATNNSKFGNLVVIYDC 77 Query: 514 RENDSRQ-KWEQIEGNSKLRHVGSNLCLDSRTA-KSGGLSVEVCGPALSQQWKF 565 + + W+ G + + +L L S A +S L++EV + SQ W+ Sbjct: 78 SKLAAEDISWDVSVGGTIMNPNYEDLALTSNKATRSTNLTMEVNTYSASQGWRV 131 >1HWM-B nrPDB Length = 266 Score = 32.3 bits (72), Expect = 0.62, Method: Compositional matrix adjust. Identities = 29/118 (24%), Positives = 49/118 (41%), Gaps = 4/118 (3%) Query: 456 CLDTL-GHFADGV-VGVYECHNAGGNQEWALTKEKSVKHMDLCLTVVDRAPGSLIKLQGC 513 C+D G+ DG + ++ C NQ+W +K+++ M C+T GS I + C Sbjct: 22 CVDVRNGYDTDGTPIQLWPCGTQR-NQQWTFYNDKTIRSMGKCMTANGLNSGSYIMITDC 80 Query: 514 RE-NDSRQKWEQIEGNSKLRHVGSNLCLDSRTAKSGGLSVEVCGPALSQQWKFTLNLQ 570 + KWE + S + + A L +E A SQ W + ++Q Sbjct: 81 STAAEDATKWEVLIDGSIINPSSGLVMTAPSGASRTTLLLENNIHAASQGWTVSNDVQ 138 >4ZFY-B nrPDB Length = 261 Score = 29.6 bits (65), Expect = 3.4, Method: Compositional matrix adjust. Identities = 28/113 (24%), Positives = 47/113 (41%), Gaps = 5/113 (4%) Query: 456 CLDTLGHF-ADGV-VGVYECHNAGGNQEWALTKEKSVKHMDLCLTVVDRAPGSLIKLQGC 513 C+D G ADG V +Y C NQ+W + +++ + CL + GS + + C Sbjct: 20 CVDVYGALTADGSRVILYPCGQQQ-NQQWTFYPDNTIRSLGKCLATSALSSGSNVVITNC 78 Query: 514 RENDSRQKWEQIEGNSKLRHVGSNLCLDSRTAKS-GGLSVEVCGPALSQQWKF 565 W + + + + S+L L + A S L+ E A Q W+ Sbjct: 79 DYLRYDDGW-MVSSSGTMMNKSSHLVLTANAATSRTNLTGENNVFAAKQAWRI 130 Score = 29.6 bits (65), Expect = 3.7, Method: Compositional matrix adjust. Identities = 24/84 (28%), Positives = 40/84 (47%), Gaps = 5/84 (5%) Query: 484 LTKEKSVKHMDLCLTVVDRAPGSLIKLQGCRENDSRQKWEQIEGNSKLRHVGSNLCLDSR 543 +T ++HM CL D + L+ C +N ++Q W ++ + NLC+ S Sbjct: 138 VTTIIGLRHM--CLEATDNDTN--VWLESCVKNKTKQYWALYSDDTIRVNNNRNLCVSSS 193 Query: 544 TAKSGGLSV-EVCGPALSQQWKFT 566 T S L V C +++Q+W FT Sbjct: 194 TDSSSKLIVIRRCDGSINQRWVFT 217 >1SMV-A nrPDB Length = 266 Score = 29.6 bits (65), Expect = 3.7, Method: Compositional matrix adjust. Identities = 21/65 (32%), Positives = 29/65 (44%), Gaps = 3/65 (4%) Query: 492 HMDLCLTVVDRAPGSLIKLQGCRENDSRQKWEQIEGNSKLRHVGSNLCLDSRTAKSGGLS 551 HM + D P S+ KL R S Q W G++ L + ++ C D+ TA S L Sbjct: 138 HMGFQYDMADTVPVSVNKLSNLRGYVSGQVW---SGSAGLCFINNSRCSDTSTAISTTLD 194 Query: 552 VEVCG 556 V G Sbjct: 195 VSELG 199 >2VLC-A nrPDB Length = 570 Score = 29.6 bits (65), Expect = 4.1, Method: Compositional matrix adjust. Identities = 22/90 (24%), Positives = 41/90 (45%), Gaps = 5/90 (5%) Query: 461 GHFADG-VVGVYEC-HNAGGNQEWALTKEKSVKHMDLCLTVVDRAPGSLIKLQGCRENDS 518 G + +G + ++ C N+ NQ W L ++ +++ CLT + G + + CR + Sbjct: 333 GKYNNGNPIQLWPCKQNSDVNQLWTLRRDGTIRSNGKCLTTNGYSAGDYVMIYDCRTPVT 392 Query: 519 RQKWEQIEGNSKLRHVGSNLCLDSRTAKSG 548 Q N + + S L L +A+SG Sbjct: 393 AASIWQFWANGTIINPQSALVL---SAESG 419 >5IW7-A nrPDB Length = 704 Score = 28.9 bits (63), Expect = 5.9, Method: Compositional matrix adjust. Identities = 22/76 (28%), Positives = 32/76 (42%), Gaps = 15/76 (19%) Query: 375 TVFARNTRR---------AAEVWMDEYKNFYYAAVPSARNVPYGNIQSRLELRKKLSCKP 425 TVF N R E W D ++F Y + +AR +G + R + KK + Sbjct: 312 TVFESNMNRDTLDEYAPEGTEDWSDYDEDFEYDGLTTARYDDHGFLPGREQTSKKAAVPK 371 Query: 426 ------FKWYLENVYP 435 KWYL++V P Sbjct: 372 GTSDYQAKWYLDDVIP 387 >6E31-A nrPDB Length = 359 Score = 28.5 bits (62), Expect = 7.6, Method: Compositional matrix adjust. Identities = 15/39 (38%), Positives = 19/39 (48%), Gaps = 6/39 (15%) Query: 222 FLDSHCECNEHWL------EPLLERVAEDRTRVVSPIID 254 F +HC+CN W E +ERV ED VV + D Sbjct: 133 FEKTHCDCNVDWCLYEIYPELQIERVFEDHENVVEVLSD 171 >1IT0-A nrPDB Length = 436 Score = 28.5 bits (62), Expect = 7.7, Method: Compositional matrix adjust. Identities = 16/44 (36%), Positives = 24/44 (54%), Gaps = 3/44 (6%) Query: 526 EGNSKLRHVGSNLCLDSRTAKSG-GLSVEV--CGPALSQQWKFT 566 G +++ VGS CLD A + G V++ C A +QQW +T Sbjct: 310 SGGGQIKGVGSGRCLDVPNASTTDGTQVQLYDCHSATNQQWTYT 353 >3CAH-A nrPDB Length = 258 Score = 28.5 bits (62), Expect = 8.1, Method: Compositional matrix adjust. Identities = 25/94 (26%), Positives = 42/94 (44%), Gaps = 3/94 (3%) Query: 479 NQEWALTKEKSVKHMDLCLTVVDRAPGSLIKLQGCRE-NDSRQKWEQIEGNSKLRHVGSN 537 NQ W + +++ M C+T GS I + C ++ KWE + + + + S Sbjct: 38 NQRWTFDSDDTIRSMGKCMTANGLNNGSNIVIFNCSTAAENAIKWE-VPIDGSIINPSSG 96 Query: 538 LCLDS-RTAKSGGLSVEVCGPALSQQWKFTLNLQ 570 L + + R A L +E A SQ W T N++ Sbjct: 97 LVMTAPRAASRTILLLEDNIYAASQGWTVTNNVK 130 >3TCA-A nrPDB Length = 291 Score = 28.5 bits (62), Expect = 8.3, Method: Compositional matrix adjust. Identities = 15/39 (38%), Positives = 19/39 (48%), Gaps = 6/39 (15%) Query: 222 FLDSHCECNEHWL------EPLLERVAEDRTRVVSPIID 254 F +HC+CN W E +ERV ED VV + D Sbjct: 65 FEKTHCDCNVDWCLYEIYPELQIERVFEDHENVVEVLSD 103 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 5AJO-A nrPDB 979 0.0 5NQA-A nrPDB 749 0.0 2D7R-A nrPDB 723 0.0 6IWR-A nrPDB 686 0.0 3RTJ-B nrPDB 163 2e-40 1RZO-B nrPDB 159 2e-39 1ABR-B nrPDB 135 5e-32 6HNQ-B nrPDB 133 2e-31 Sequences not found previously or not previously below threshold: 2Q3N-B nrPDB 131 9e-31 2VLC-A nrPDB 123 3e-28 2MLL-B nrPDB 118 6e-27 3D7W-B nrPDB 118 7e-27 1YF8-B nrPDB 116 2e-26 1HWM-B nrPDB 105 4e-23 3CAH-A nrPDB 103 2e-22 1GGP-B nrPDB 93 4e-19 5Y97-C nrPDB 81 1e-15 3A22-A nrPDB 81 1e-15 4ZFY-B nrPDB 71 2e-12 1IT0-A nrPDB 69 4e-12 2Z87-A nrPDB 69 6e-12 3WN1-A nrPDB 67 3e-11 2Z49-A nrPDB 59 7e-09 5TZ8-A nrPDB 57 2e-08 5MLZ-A nrPDB 55 1e-07 5EKE-A nrPDB 41 0.001 3L7K-A nrPDB 41 0.001 5OCR-A nrPDB 34 0.17 5KY2-A nrPDB 32 0.58 3OOQ-A nrPDB 32 0.72 2B4T-O nrPDB 31 1.4 5AJ4-Ba nrPDB 31 1.5 3STH-A nrPDB 30 2.4 3N42-F nrPDB 29 5.1 2XFC-A nrPDB 29 5.1 >5AJO-A nrPDB Length = 571 Score = 979 bits (2531), Expect = 0.0, Method: Composition-based stats. Identities = 570/571 (99%), Positives = 571/571 (100%) Query: 1 MRRRSRMLLCFAFLWVLGIAYYMYSGGGSALAGGAGGGAGRKEDWNEIDPIKKKDLHHSN 60 MRRRSRMLLCFAFLWVLGIAYYMYSGGGSALAGGAGGGAGRKEDWNEIDPIKKKDLHHSN Sbjct: 1 MRRRSRMLLCFAFLWVLGIAYYMYSGGGSALAGGAGGGAGRKEDWNEIDPIKKKDLHHSN 60 Query: 61 GEEKAQSMETLPPGKVRWPDFNQEAYVGGTMVRSGQDPYARNKFNQVESDKLRMDRAIPD 120 GEEKAQSMETLPPGKVRWPDFNQEAYVGGTMVRSGQDPYARNKFNQVESDKLRMDRAIPD Sbjct: 61 GEEKAQSMETLPPGKVRWPDFNQEAYVGGTMVRSGQDPYARNKFNQVESDKLRMDRAIPD 120 Query: 121 TRHDQCQRKQWRVDLPATSVVITFHNEARSALLRTVVSVLKKSPPHLIKEIILVDDYSND 180 TRHDQCQRKQWRVDLPATSVVITFHNEARSALLRTVVSVLKKSPPHLIKEIILVDDYSND Sbjct: 121 TRHDQCQRKQWRVDLPATSVVITFHNEARSALLRTVVSVLKKSPPHLIKEIILVDDYSND 180 Query: 181 PEDGALLGKIEKVRVLRNDRREGLMRSRVRGADAAQAKVLTFLDSHCECNEHWLEPLLER 240 PEDGALLGKIEKVRVLRNDRREGLMRSRVRGADAAQAKVLTFLDSHCECNEHWLEPLLER Sbjct: 181 PEDGALLGKIEKVRVLRNDRREGLMRSRVRGADAAQAKVLTFLDSHCECNEHWLEPLLER 240 Query: 241 VAEDRTRVVSPIIDVINMDNFQYVGASADLKGGFDWNLVFKWDYMTPEQRRSRQGNPVAP 300 VAEDRTRVVSPIIDVINMDNFQYVGASADLKGGFDWNLVFKWDYMTPEQRRSRQGNPVAP Sbjct: 241 VAEDRTRVVSPIIDVINMDNFQYVGASADLKGGFDWNLVFKWDYMTPEQRRSRQGNPVAP 300 Query: 301 IKTPMIAGGLFVMDKFYFEELGKYDMMMDVWGGENLEISFRVWQCGGSLEIIPCSRVGHV 360 IKTPMIAGGLFVMDKFYFEELGKYDMMMDVWGGENLEISFRVWQCGGSLEIIPCSRVGHV Sbjct: 301 IKTPMIAGGLFVMDKFYFEELGKYDMMMDVWGGENLEISFRVWQCGGSLEIIPCSRVGHV 360 Query: 361 FRKQHPYTFPGGSGTVFARNTRRAAEVWMDEYKNFYYAAVPSARNVPYGNIQSRLELRKK 420 FRKQHPYTFPGGSGTVFARNTRRAAEVWMDEYKNFYYAAVPSARNVPYGNIQSRLELRKK Sbjct: 361 FRKQHPYTFPGGSGTVFARNTRRAAEVWMDEYKNFYYAAVPSARNVPYGNIQSRLELRKK 420 Query: 421 LSCKPFKWYLENVYPELRVPDHQDIAFGALQQGTNCLDTLGHFADGVVGVYECHNAGGNQ 480 LSCKPFKWYLENVYPELRVPDHQDIAFGALQQGTNCLDTLGHFADGVVGVYECHNAGGNQ Sbjct: 421 LSCKPFKWYLENVYPELRVPDHQDIAFGALQQGTNCLDTLGHFADGVVGVYECHNAGGNQ 480 Query: 481 EWALTKEKSVKHMDLCLTVVDRAPGSLIKLQGCRENDSRQKWEQIEGNSKLRHVGSNLCL 540 EWALTKEKSVKHMDLCLTVVDRAPGSLIKLQGCRE+DSRQKWEQIEGNSKLRHVGSNLCL Sbjct: 481 EWALTKEKSVKHMDLCLTVVDRAPGSLIKLQGCREDDSRQKWEQIEGNSKLRHVGSNLCL 540 Query: 541 DSRTAKSGGLSVEVCGPALSQQWKFTLNLQQ 571 DSRTAKSGGLSVEVCGPALSQQWKFTLNLQQ Sbjct: 541 DSRTAKSGGLSVEVCGPALSQQWKFTLNLQQ 571 >5NQA-A nrPDB Length = 578 Score = 749 bits (1934), Expect = 0.0, Method: Composition-based stats. Identities = 224/574 (39%), Positives = 321/574 (55%), Gaps = 44/574 (7%) Query: 4 RSRMLLCFAFLWVLGIAYYMYSGGGSALAGGAGGGAGRKEDWNEIDPIKKKDLHHSNGEE 63 +S +LL F L +AY S AG G R E+ + DL N E+ Sbjct: 10 KSCLLLAF-----LTVAYIFVELLVSTFHASAGAGRAR-----ELGSRRLSDLQ-KNTED 58 Query: 64 KAQSMETLPPGKVR----WPDFNQEAYVGGTMVRSGQDPYARNKFNQVESDKLRMDRAIP 119 ++ + PP R W + + + ++ ++ R N SD++ + R I Sbjct: 59 LSRPLYKKPPADSRALGEWGKAS-KLQLNEDELKQQEELIERYAINIYLSDRISLHRHIE 117 Query: 120 DTRHDQCQRKQWRV-DLPATSVVITFHNEARSALLRTVVSVLKKSPPHLIKEIILVDDYS 178 D R +C+ +++ LP TSV+I F+NEA S LLRT+ SVL+ SP L+KEIILVDD S Sbjct: 118 DKRMYECKSQKFNYRTLPTTSVIIAFYNEAWSTLLRTIHSVLETSPAVLLKEIILVDDLS 177 Query: 179 N----DPEDGALLGKIEKVRVLRNDRREGLMRSRVRGADAAQAKVLTFLDSHCECNEHWL 234 + + + +++VR++R ++REGL+R+R+ GA A VLTFLD HCECN WL Sbjct: 178 DRVYLKTQLETYISNLDRVRLIRTNKREGLVRARLIGATFATGDVLTFLDCHCECNSGWL 237 Query: 235 EPLLERVAEDRTRVVSPIIDVINMDNFQ-YVGASADLKGGFDWNLVFKWDYMTPEQRRSR 293 EPLLER+ D T VV P+ID I+ + F+ Y+ + GGFDW L F+W + P+Q R R Sbjct: 238 EPLLERIGRDETAVVCPVIDTIDWNTFEFYMQIGEPMIGGFDWRLTFQW-HSVPKQERDR 296 Query: 294 QGNPVAPIKTPMIAGGLFVMDKFYFEELGKYDMMMDVWGGENLEISFRVWQCGGSLEIIP 353 + + + PI++P +AGGLF + K YF+ LG YD M+VWGGENLE+SFRVWQCGG LEI P Sbjct: 297 RISRIDPIRSPTMAGGLFAVSKKYFQYLGTYDTGMEVWGGENLELSFRVWQCGGKLEIHP 356 Query: 354 CSRVGHVFRKQHPYTFPGGSGTVFARNTRRAAEVWMDEYKNFYYAAVPSARNVPYGNIQS 413 CS VGHVF K+ PY P F +NT RAAEVWMDEYK +Y P AR YG+I Sbjct: 357 CSHVGHVFPKRAPYARPN-----FLQNTARAAEVWMDEYKEHFYNRNPPARKEAYGDISE 411 Query: 414 RLELRKKLSCKPFKWYLENVYPELRVPDHQDIAFGALQQ---GTNCLDTLG---HFADGV 467 R LR++L CK F WYL+NV+P L VP+ + GA++ + CLD + Sbjct: 412 RKLLRERLRCKSFDWYLKNVFPNLHVPEDRPGWHGAIRSRGISSECLDYNSPDNNPTGAN 471 Query: 468 VGVYECHNAGGNQEWALTKEKSVKHM---DLCLTVVDRAPGSLIKLQGCREN----DSRQ 520 + ++ CH GGNQ + T K ++ +LC V ++ + + +Q C ++ + Sbjct: 472 LSLFGCHGQGGNQFFEYTSNKEIRFNSVTELCAEVPEQK--NYVGMQNCPKDGFPVPANI 529 Query: 521 KWEQIEGNSKLRHVGSNLCLDSRTAKSGGLSVEV 554 W + + + H S LCL + G V++ Sbjct: 530 IW-HFKEDGTIFHPHSGLCLSAYRTPEGRPDVQM 562 >2D7R-A nrPDB Length = 570 Score = 723 bits (1865), Expect = 0.0, Method: Composition-based stats. Identities = 208/586 (35%), Positives = 307/586 (52%), Gaps = 74/586 (12%) Query: 26 GGGSALAGGAGGGAGRKE-------------DWNEIDPIKKKDLHHSNGEEKAQSMETLP 72 G G+A+A AG G+ ++ DW++ + I++ NGE+ Sbjct: 9 GSGAAVAPAAGQGSHSRQKKTFFLGDGQKLKDWHDKEAIRRDAQRVGNGEQG-------- 60 Query: 73 PGKVRWPDFNQEAYVGGTMVRSGQDPYARNKFNQVESDKLRMDRAIPDTRHDQCQRKQWR 132 Y R Q Y N FN SDK+ ++R++PD RH C K++ Sbjct: 61 -----------RPYPMTDAERVDQ-AYRENGFNIYVSDKISLNRSLPDIRHPNCNSKRYL 108 Query: 133 VDLPATSVVITFHNEARSALLRTVVSVLKKSPPHLIKEIILVDDYSNDPEDG----ALLG 188 LP TS++I FHNE S+LLRTV SVL +SPP L+ EI+LVDD+S+ + Sbjct: 109 ETLPNTSIIIPFHNEGWSSLLRTVHSVLNRSPPELVAEIVLVDDFSDREHLKKPLEDYMA 168 Query: 189 KIEKVRVLRNDRREGLMRSRVRGADAAQAKVLTFLDSHCECNEHWLEPLLERVAEDRTRV 248 VR+LR +REGL+R+R+ GA A V+TFLDSHCE N +WL PLL+R+A +R + Sbjct: 169 LFPSVRILRTKKREGLIRTRMLGASVATGDVITFLDSHCEANVNWLPPLLDRIARNRKTI 228 Query: 249 VSPIIDVINMDNFQYVGASAD-LKGGFDWNLVFKWDYMTPEQRRSRQGNPVAPIKTPMIA 307 V P+IDVI+ D+F+Y + D ++G FDW + +K + PE +++ +P P ++P++A Sbjct: 229 VCPMIDVIDHDDFRYETQAGDAMRGAFDWEMYYKRIPIPPELQKA---DPSDPFESPVMA 285 Query: 308 GGLFVMDKFYFEELGKYDMMMDVWGGENLEISFRVWQCGGSLEIIPCSRVGHVFRKQHPY 367 GGLF +D+ +F ELG YD +++WGGE EISF+VW CGG +E IPCSRVGH++RK PY Sbjct: 286 GGLFAVDRKWFWELGGYDPGLEIWGGEQYEISFKVWMCGGRMEDIPCSRVGHIYRKYVPY 345 Query: 368 TFPGGSGTVFARNTRRAAEVWMDEYKNFYYAAVPSARNVPYGNIQSRLELRKKLSCKPFK 427 P +G ARN +R AEVWMDEY + Y P R++ G++ + +LR L+CK FK Sbjct: 346 KVP--AGVSLARNLKRVAEVWMDEYAEYIYQRRPEYRHLSAGDVAVQKKLRSSLNCKSFK 403 Query: 428 WYLENV-------YPELRVPDHQDIAFGALQQ-GTN-CLDTLGHFADGVVGVYECHNAGG 478 W++ + YP + P A+G ++ GT C DT + + C G Sbjct: 404 WFMTKIAWDLPKFYPPVEPP---AAAWGEIRNVGTGLCADTKHGALGSPLRLEGCVRGRG 460 Query: 479 NQEW------ALTKEKSVKHMD------LCLTVVDRAPGSLIKLQGCRENDSRQKWEQIE 526 W T + ++ D C + S + L C Q W + Sbjct: 461 EAAWNNMQVFTFTWREDIRPGDPQHTKKFCFDAISHT--SPVTLYDCHSMKGNQLW-KYR 517 Query: 527 GNSKLRHVGSNLCLDSRTAKSGGLSVEVCGP-ALSQQWKF--TLNL 569 + L H S C+D + + + C P +L+QQW F T + Sbjct: 518 KDKTLYHPVSGSCMDC-SESDHRIFMNTCNPSSLTQQWLFEHTNST 562 >6IWR-A nrPDB Length = 597 Score = 686 bits (1770), Expect = 0.0, Method: Composition-based stats. Identities = 181/525 (34%), Positives = 299/525 (56%), Gaps = 30/525 (5%) Query: 66 QSMETLPPGKVRWPDFNQEAYVGGTMVRSG-QDPYARNKFNQVESDKLRMDRAIPDTRHD 124 + E PPG V P + V G + Q FN V SD + +DR++ D R + Sbjct: 76 EPKEPEPPGVVGGPGEKAKPLVLGPEFKQAIQASIKEFGFNMVASDMISLDRSVNDLRQE 135 Query: 125 QCQRKQWRVDLPATSVVITFHNEARSALLRTVVSVLKKSPPHLIKEIILVDDYSNDPEDG 184 +C+ + +L +SVVI FHNE S L+RTV SV+K++P + EI+L+DD+SN Sbjct: 136 ECKYWHYDENLLTSSVVIVFHNEGWSTLMRTVHSVIKRTPRKYLAEIVLIDDFSNKEHLK 195 Query: 185 ALLGKIEK-----VRVLRNDRREGLMRSRVRGADAAQ-AKVLTFLDSHCECNEHWLEPLL 238 L + K V+V RN+RREGL+++R GA A+ +VL +LD+HCE +W PL+ Sbjct: 196 EKLDEYIKLWNGLVKVFRNERREGLIQARSIGAQKAKLGQVLIYLDAHCEVAVNWYAPLV 255 Query: 239 ERVAEDRTRVVSPIIDVINMDNFQYV---GASAD--LKGGFDWNLVFKWDYMTPEQRRSR 293 +++DRT P+IDVIN + ++ + G D +G +DW++++K +TP+++R R Sbjct: 256 APISKDRTICTVPLIDVINGNTYEIIPQGGGDEDGYARGAWDWSMLWKRVPLTPQEKRLR 315 Query: 294 QGNPVAPIKTPMIAGGLFVMDKFYFEELGKYDMMMDVWGGENLEISFRVWQCGGSLEIIP 353 + P ++P +AGGLF +++ +F ELG YD + +WGGEN EIS+++WQCGG L +P Sbjct: 316 KTK-TEPYRSPAMAGGLFAIEREFFFELGLYDPGLQIWGGENFEISYKIWQCGGKLLFVP 374 Query: 354 CSRVGHVFRKQ-----HPYTFPGGSGTVFARNTRRAAEVWMDEYKNFYYAAVPSARNVPY 408 CSRVGH++R + P + G S T+ +N R EVW DEYK+++YA+ P ++ +PY Sbjct: 375 CSRVGHIYRLEGWQGNPPPIYVGSSPTL--KNYVRVVEVWWDEYKDYFYASRPESQALPY 432 Query: 409 GNIQSRLELRKKLSCKPFKWYLENVYPELR---VPDHQDIAFGALQ--QGTNCLDTLGHF 463 G+I + R+ +CK FKW++E + ++ +++ +G ++ + C+D++G Sbjct: 433 GDISELKKFREDHNCKSFKWFMEEIAYDITSHYPLPPKNVDWGEIRGFETAYCIDSMGKT 492 Query: 464 ADGVVGVYECHNAGGNQEWALTKEKSVKHMDLCLTVVDRAPGSLIKLQGCRENDSRQKWE 523 G V + CH GGNQ + + + + D CLT A GS + + C N+ ++ W+ Sbjct: 493 NGGFVELGPCHRMGGNQLFRINEANQLMQYDQCLT--KGADGSKVMITHCNLNEFKE-WQ 549 Query: 524 QIEGNSKLRHVGSNLCLDSRTAKSGGLSVEVCGPA-LSQQWKFTL 567 + + H+ S CLD R+ + + C + +Q+W+ Sbjct: 550 YFKNLHRFTHIPSGKCLD-RSEVLHQVFISNCDSSKTTQKWEMNN 593 >3RTJ-B nrPDB Length = 262 Score = 163 bits (412), Expect = 2e-40, Method: Composition-based stats. Identities = 34/119 (28%), Positives = 56/119 (47%), Gaps = 4/119 (3%) Query: 456 CLDTL-GHFADGV-VGVYEC-HNAGGNQEWALTKEKSVKHMDLCLTVVDRAPGSLIKLQG 512 C+D G F +G + ++ C N NQ W L ++ +++ CLT +PG + + Sbjct: 20 CVDVRDGRFHNGNAIQLWPCKSNTDANQLWTLKRDNTIRSNGKCLTTYGYSPGVYVMIYD 79 Query: 513 CRENDSRQKWEQIEGNSKLRHVGSNLCLDSRTAKSG-GLSVEVCGPALSQQWKFTLNLQ 570 C + QI N + + S+L L + + SG L+V+ A+SQ W T N Q Sbjct: 80 CNTAATDATRWQIWDNGTIINPRSSLVLAATSGNSGTTLTVQTNIYAVSQGWLPTNNTQ 138 Score = 57.1 bits (136), Expect = 2e-08, Method: Composition-based stats. Identities = 22/87 (25%), Positives = 40/87 (45%), Gaps = 4/87 (4%) Query: 462 HFADGVVGVYECHNAGGNQEWALTKEKSVKHM---DLCLTVVDRAPGSLIKLQGCRENDS 518 G V + +C + Q+WAL + S++ D CLT +++K+ C S Sbjct: 153 QANSGQVWIEDCSSEKAEQQWALYADGSIRPQQNRDNCLTSDSNIRETVVKILSCGPASS 212 Query: 519 RQKWEQIEGNSKLRHVGSNLCLDSRTA 545 Q+W + + + ++ S L LD R + Sbjct: 213 GQRWM-FKNDGTILNLYSGLVLDVRAS 238 Score = 36.7 bits (83), Expect = 0.031, Method: Composition-based stats. Identities = 19/78 (24%), Positives = 32/78 (41%), Gaps = 6/78 (7%) Query: 493 MDLCLTVVDRAPGSLIKLQGCRENDSRQKWEQIEGNSKLRHVGSNLCLDSRTA-KSGGLS 551 LCL +A + ++ C + Q+W S + CL S + + + Sbjct: 148 YGLCL----QANSGQVWIEDCSSEKAEQQWALYADGSIRPQQNRDNCLTSDSNIRETVVK 203 Query: 552 VEVCGPALS-QQWKFTLN 568 + CGPA S Q+W F + Sbjct: 204 ILSCGPASSGQRWMFKND 221 Score = 31.3 bits (69), Expect = 1.4, Method: Composition-based stats. Identities = 18/75 (24%), Positives = 27/75 (36%), Gaps = 4/75 (5%) Query: 451 QQGTNCLDTLGHFADGVVGVYECHNAGGNQEWALTKEKSV--KHMDLCLTVVDRAPG-SL 507 Q NCL + + + VV + C A Q W + ++ + L L V P Sbjct: 185 QNRDNCLTSDSNIRETVVKILSCGPASSGQRWMFKNDGTILNLYSGLVLDVRASDPSLKQ 244 Query: 508 IKLQGCRENDSRQKW 522 I L + Q W Sbjct: 245 IILYPLHGDP-NQIW 258 >1RZO-B nrPDB Length = 262 Score = 159 bits (403), Expect = 2e-39, Method: Composition-based stats. Identities = 33/119 (27%), Positives = 52/119 (43%), Gaps = 4/119 (3%) Query: 456 CLDTLGH--FADGVVGVYEC-HNAGGNQEWALTKEKSVKHMDLCLTVVDRAPGSLIKLQG 512 C+D G F + ++ C N NQ W L K+ +++ CLT+ +P + + Sbjct: 20 CVDVTGEEFFDGNPIQLWPCKSNTDWNQLWTLRKDSTIRSNGKCLTISKSSPRQQVVIYN 79 Query: 513 CRENDSRQKWEQIEGNSKLRHVGSNLCLDSRTAKSGG-LSVEVCGPALSQQWKFTLNLQ 570 C QI N + + S L L + + SG L+V+ A+SQ W T N Q Sbjct: 80 CSTATVGATRWQIWDNRTIINPRSGLVLAATSGNSGTKLTVQTNIYAVSQGWLPTNNTQ 138 Score = 60.9 bits (146), Expect = 1e-09, Method: Composition-based stats. Identities = 26/109 (23%), Positives = 47/109 (43%), Gaps = 6/109 (5%) Query: 462 HFADGVVGVYECHNAGGNQEWALTKEKSVKHM---DLCLTVVDRAPGSLIKLQGCRENDS 518 G V + +C + Q+WAL + S++ D CLT G+++K+ C S Sbjct: 153 QANSGKVWLEDCTSEKAEQQWALYADGSIRPQQNRDNCLTTDANIKGTVVKILSCGPASS 212 Query: 519 RQKWEQIEGNSKLRHVGSNLCLDSRTA--KSGGLSVEVCGPALSQQWKF 565 Q+W + + + ++ + L LD R + + V L+Q W Sbjct: 213 GQRWM-FKNDGTILNLYNGLVLDVRRSDPSLKQIIVHPFHGNLNQIWLP 260 Score = 35.9 bits (81), Expect = 0.049, Method: Composition-based stats. Identities = 19/78 (24%), Positives = 31/78 (39%), Gaps = 6/78 (7%) Query: 493 MDLCLTVVDRAPGSLIKLQGCRENDSRQKWEQIEGNSKLRHVGSNLCLDSRTAKSGG-LS 551 +CL +A + L+ C + Q+W S + CL + G + Sbjct: 148 YGMCL----QANSGKVWLEDCTSEKAEQQWALYADGSIRPQQNRDNCLTTDANIKGTVVK 203 Query: 552 VEVCGPALS-QQWKFTLN 568 + CGPA S Q+W F + Sbjct: 204 ILSCGPASSGQRWMFKND 221 Score = 34.0 bits (76), Expect = 0.17, Method: Composition-based stats. Identities = 17/74 (22%), Positives = 25/74 (33%), Gaps = 2/74 (2%) Query: 451 QQGTNCLDTLGHFADGVVGVYECHNAGGNQEWALTKEKSV--KHMDLCLTVVDRAPGSLI 508 Q NCL T + VV + C A Q W + ++ + L L V P Sbjct: 185 QNRDNCLTTDANIKGTVVKILSCGPASSGQRWMFKNDGTILNLYNGLVLDVRRSDPSLKQ 244 Query: 509 KLQGCRENDSRQKW 522 + + Q W Sbjct: 245 IIVHPFHGNLNQIW 258 >1ABR-B nrPDB Length = 267 Score = 135 bits (339), Expect = 5e-32, Method: Composition-based stats. Identities = 29/118 (24%), Positives = 53/118 (44%), Gaps = 4/118 (3%) Query: 456 CLDT--LGHFADGVVGVYECH-NAGGNQEWALTKEKSVKHMDLCLTVVDRAPGSLIKLQG 512 C+D G+ + +++C NQ W L +K+++ CLT APGS + + Sbjct: 25 CVDVYDNGYHNGNRIIMWKCKDRLEENQLWTLKSDKTIRSNGKCLTTYGYAPGSYVMIYD 84 Query: 513 CRENDSRQKWEQIEGNSKLRHVGSNLCLDSRTAKSGG-LSVEVCGPALSQQWKFTLNL 569 C + + +I N + + S L L + ++ GG L+V+ + Q W+ N Sbjct: 85 CTSAVAEATYWEIWDNGTIINPKSALVLSAESSSMGGTLTVQTNEYLMRQGWRTGNNT 142 Score = 49.4 bits (116), Expect = 4e-06, Method: Composition-based stats. Identities = 28/119 (23%), Positives = 48/119 (40%), Gaps = 16/119 (13%) Query: 458 DTLGHFADGVVGVYECHNAGGNQEWALTKEKSVKH---MDLCLTVVDRAPGSLIKLQGCR 514 D V + +C + Q+WAL + S++ + CLT D GS I L GC Sbjct: 154 DLCMQAQGSNVWMADCDSNKKEQQWALYTDGSIRSVQNTNNCLTSKDHKQGSTILLMGCS 213 Query: 515 ENDSRQKWEQIEGNSKLRHVGSNLCLDSRTAKSGGLSVEVCGPALSQ--QWKFTLNLQQ 571 + Q+W + + + + ++ +D V+ P+L Q W +T Q Sbjct: 214 NGWASQRWV-FKNDGSIYSLYDDMVMD----------VKGSDPSLKQIILWPYTGKPNQ 261 Score = 41.7 bits (96), Expect = 0.001, Method: Composition-based stats. Identities = 16/81 (19%), Positives = 28/81 (34%), Gaps = 2/81 (2%) Query: 444 DIAFGALQQGTNCLDTLGHFADGVVGVYECHNAGGNQEWALTKEKSVKH--MDLCLTVVD 501 D + ++Q NCL + H + + C N +Q W + S+ D+ + V Sbjct: 183 DGSIRSVQNTNNCLTSKDHKQGSTILLMGCSNGWASQRWVFKNDGSIYSLYDDMVMDVKG 242 Query: 502 RAPGSLIKLQGCRENDSRQKW 522 P + Q W Sbjct: 243 SDPSLKQIILWPYTGKPNQIW 263 >6HNQ-B nrPDB Length = 345 Score = 133 bits (334), Expect = 2e-31, Method: Composition-based stats. Identities = 38/126 (30%), Positives = 65/126 (51%), Gaps = 14/126 (11%) Query: 132 RVDLPATSVVI-TFHNEARSALLRTVVSVLKKSPPHLIKEIILVDDYSNDPEDGALLGKI 190 R + SV++ TF+N + L RT+ SVL ++ E+I++DD+SND +G L I Sbjct: 16 RGSMKKVSVIMPTFNNGEK--LHRTISSVLNQTMKSTDYELIIIDDHSND--NGETLNVI 71 Query: 191 EKVRVLRNDRREGLMRS-------RVRGADAAQAKVLTFLDSHCECNEHWLEPLLERVAE 243 +K + L R + L ++ R G ++A+ + FLDS +E LE L E Sbjct: 72 KKYKGLV--RFKQLKKNSGNASVPRNTGLKMSKAEYVFFLDSDDLLHERALEDLYNYGKE 129 Query: 244 DRTRVV 249 + + ++ Sbjct: 130 NNSDLI 135 >2Q3N-B nrPDB Length = 267 Score = 131 bits (329), Expect = 9e-31, Method: Composition-based stats. Identities = 26/118 (22%), Positives = 52/118 (44%), Gaps = 4/118 (3%) Query: 456 CLDTLGHF--ADGVVGVYECHNA-GGNQEWALTKEKSVKHMDLCLTVVDRAPGSLIKLQG 512 C+D + + +++C + NQ W L +K+++ CLT APG+ + + Sbjct: 25 CVDVSDNAYNNGNPIILWKCKDQLEVNQLWTLKSDKTIRSKGKCLTTYGYAPGNYVMIYD 84 Query: 513 CRENDSRQKWEQIEGNSKLRHVGSNLCLDSRTAKSGG-LSVEVCGPALSQQWKFTLNL 569 C + + I N + + S L L + ++ GG L+V+ + Q W+ + Sbjct: 85 CSSAVAEATYWDIWDNGTIINPKSGLVLSAESSSMGGTLTVQKNDYRMRQGWRTGNDT 142 Score = 53.2 bits (126), Expect = 3e-07, Method: Composition-based stats. Identities = 23/115 (20%), Positives = 47/115 (40%), Gaps = 16/115 (13%) Query: 462 HFADGVVGVYECHNAGGNQEWALTKEKSVKH---MDLCLTVVDRAPGSLIKLQGCRENDS 518 + + C Q+WA+ + S++ + CLT + G+ I + GC + Sbjct: 158 EAHGNSMWLDVCDITKEEQQWAVYPDGSIRPVQNTNNCLTCEEHKQGATIVMMGCSNAWA 217 Query: 519 RQKWEQIEGNSKLRHVGSNLCLDSRTAKSGGLSVEVCGPALSQ--QWKFTLNLQQ 571 Q+W + + + ++ ++ +D V+ P+L Q W +T N Q Sbjct: 218 SQRWV-FKSDGTIYNLYDDMVMD----------VKSSDPSLKQIILWPYTGNANQ 261 Score = 39.0 bits (89), Expect = 0.006, Method: Composition-based stats. Identities = 18/92 (19%), Positives = 33/92 (35%), Gaps = 10/92 (10%) Query: 433 VYPELRVPDHQDIAFGALQQGTNCLDTLGHFADGVVGVYECHNAGGNQEWALTKEKSV-- 490 VYP+ + +Q NCL H + + C NA +Q W + ++ Sbjct: 180 VYPDGSIRP--------VQNTNNCLTCEEHKQGATIVMMGCSNAWASQRWVFKSDGTIYN 231 Query: 491 KHMDLCLTVVDRAPGSLIKLQGCRENDSRQKW 522 + D+ + V P + ++ Q W Sbjct: 232 LYDDMVMDVKSSDPSLKQIILWPYTGNANQMW 263 >2VLC-A nrPDB Length = 570 Score = 123 bits (308), Expect = 3e-28, Method: Composition-based stats. Identities = 26/119 (21%), Positives = 49/119 (41%), Gaps = 4/119 (3%) Query: 456 CLDTL-GHFADG-VVGVYEC-HNAGGNQEWALTKEKSVKHMDLCLTVVDRAPGSLIKLQG 512 C+ G + +G + ++ C N+ NQ W L ++ +++ CLT + G + + Sbjct: 327 CVRVRDGKYNNGNPIQLWPCKQNSDVNQLWTLRRDGTIRSNGKCLTTNGYSAGDYVMIYD 386 Query: 513 CRENDSRQKWEQIEGNSKLRHVGSNLCLDSRTA-KSGGLSVEVCGPALSQQWKFTLNLQ 570 CR + Q N + + S L L + + L+V+ A Q W N + Sbjct: 387 CRTPVTAASIWQFWANGTIINPQSALVLSAESGNPRTTLTVQADIYASRQGWLAGNNTE 445 Score = 47.1 bits (110), Expect = 2e-05, Method: Composition-based stats. Identities = 21/115 (18%), Positives = 42/115 (36%), Gaps = 5/115 (4%) Query: 458 DTLGHFADGVVGVYECHNAGGNQEWALTKEKSVKHM---DLCLTVVDRAPGSLIKLQGCR 514 D + V EC ++ Q+WAL + S++ D CLT D I + Sbjct: 456 DLCMQANGDAMWVVECESSKAEQKWALYPDGSIRPHQDRDRCLTSTDNHSQGSIIIISSC 515 Query: 515 ENDSRQKWEQIEGNSKLRHVGSNLCLDSRTA--KSGGLSVEVCGPALSQQWKFTL 567 S + + + ++ + L +D + + + + +Q+W L Sbjct: 516 SPGSEGQRWVFMNDGTILNLKNGLVMDVKGSDPSLHQIIIWPATGKPNQKWLPLL 570 >2MLL-B nrPDB Length = 255 Score = 118 bits (296), Expect = 6e-27, Method: Composition-based stats. Identities = 29/123 (23%), Positives = 49/123 (39%), Gaps = 5/123 (4%) Query: 451 QQGTNCLDTLGH-FADGV-VGVYEC-HNAGGNQEWALTKEKSVKHMDLCLTVVDRAPGSL 507 + G N +D F DG + ++ N NQ W + ++ +++ CLT G Sbjct: 13 RNGMN-VDVRDDDFHDGNQIQLWPSKSNNDPNQLWTIKRDGTIRSNGSCLTTYGYTAGVY 71 Query: 508 IKLQGCRENDSRQKWEQIEGNSKLRHVGSNLCLDSRTAKSG-GLSVEVCGPALSQQWKFT 566 + + C QI GN + + SNL L + + G L+V+ L Q W Sbjct: 72 VMIFDCATAVGEATVWQIWGNGTIINPRSNLVLAASSGIKGTTLTVQTLDYTLGQGWLAG 131 Query: 567 LNL 569 + Sbjct: 132 NDT 134 Score = 46.7 bits (109), Expect = 2e-05, Method: Composition-based stats. Identities = 21/111 (18%), Positives = 39/111 (35%), Gaps = 6/111 (5%) Query: 458 DTLGHFADGVVGVYECHNAGGNQEWALTKEKSVKHMD---LCLTVVDRAPGSLIKLQGCR 514 D G V V C + ++ WAL + S++ CLT + + + C Sbjct: 146 DLCMESGGGSVTVETCSSGKADK-WALYGDGSIRPEQNQAQCLTSGGDSVAG-VNIVSCS 203 Query: 515 ENDSRQKWEQIEGNSKLRHVGSNLCLDSRTAKSGGLSVEVCGPALSQQWKF 565 S Q+W + ++ + L +D G + + +Q W Sbjct: 204 GAASGQRWV-FTNEGAILNLKNGLAMDVANPGGGRIIIYPATGKPNQMWLP 253 >3D7W-B nrPDB Length = 265 Score = 118 bits (295), Expect = 7e-27, Method: Composition-based stats. Identities = 27/110 (24%), Positives = 44/110 (40%), Gaps = 3/110 (2%) Query: 463 FADGV-VGVYEC-HNAGGNQEWALTKEKSVKHMDLCLTVVDRAPGSLIKLQGCRENDSRQ 520 F DG + ++ N NQ W + K+ +++ CLT G + + C Sbjct: 29 FHDGNQIQLWPSKSNNDPNQLWTIKKDGTIRSNGSCLTTYGYTAGVYVMIFDCNTAVREA 88 Query: 521 KWEQIEGNSKLRHVGSNLCLDSRTAKSG-GLSVEVCGPALSQQWKFTLNL 569 QI GN + + SNL L + + G L+V+ L Q W + Sbjct: 89 TIWQIWGNGTIINPRSNLVLAASSGIKGTTLTVQTLDYTLGQGWLAGNDT 138 Score = 49.7 bits (117), Expect = 3e-06, Method: Composition-based stats. Identities = 25/113 (22%), Positives = 41/113 (36%), Gaps = 6/113 (5%) Query: 458 DTLGHFADGVVGVYECHNAGGNQEWALTKEKSVKH---MDLCLTVVDRAPGSLIKLQGCR 514 D A G V V C NQ WAL + S++ CLT + ++I + C Sbjct: 150 DLCMESAGGSVYVETCTAGQENQRWALYGDGSIRPKQLQSQCLTNGRDSISTVINIVSCS 209 Query: 515 ENDSRQKWEQIEGNSKLRHVGSNLCLDSRTAKSG--GLSVEVCGPALSQQWKF 565 S Q+W + ++ + L +D A + + +Q W Sbjct: 210 AGSSGQRWV-FTNEGAILNLKNGLAMDVAQANPSLQRIIIYPATGNPNQMWLP 261 >1YF8-B nrPDB Length = 255 Score = 116 bits (291), Expect = 2e-26, Method: Composition-based stats. Identities = 29/123 (23%), Positives = 49/123 (39%), Gaps = 5/123 (4%) Query: 451 QQGTNCLDTLGH-FADGV-VGVYEC-HNAGGNQEWALTKEKSVKHMDLCLTVVDRAPGSL 507 + G N +D F DG + ++ N NQ W + ++ +++ CLT G Sbjct: 13 RNGMN-VDVRDDDFHDGNQIQLWPSKSNNDPNQLWTIKRDGTIRSNGSCLTTYGYTAGVY 71 Query: 508 IKLQGCRENDSRQKWEQIEGNSKLRHVGSNLCLDSRTAKSG-GLSVEVCGPALSQQWKFT 566 + + C QI GN + + SNL L + + G L+V+ L Q W Sbjct: 72 VMIFDCNTAVREATIWQIWGNGTIINPRSNLALAASSGIKGTTLTVQTLDYTLGQGWLAG 131 Query: 567 LNL 569 + Sbjct: 132 NDT 134 >1HWM-B nrPDB Length = 266 Score = 105 bits (263), Expect = 4e-23, Method: Composition-based stats. Identities = 24/118 (20%), Positives = 47/118 (39%), Gaps = 4/118 (3%) Query: 456 CLDTLGH--FADGVVGVYECHNAGGNQEWALTKEKSVKHMDLCLTVVDRAPGSLIKLQGC 513 C+D + ++ C NQ+W +K+++ M C+T GS I + C Sbjct: 22 CVDVRNGYDTDGTPIQLWPCGTQR-NQQWTFYNDKTIRSMGKCMTANGLNSGSYIMITDC 80 Query: 514 RENDSRQKWEQIEGNSKLRHVGSNLCLDSRTAKS-GGLSVEVCGPALSQQWKFTLNLQ 570 ++ + + + S L + + + S L +E A SQ W + ++Q Sbjct: 81 STAAEDATKWEVLIDGSIINPSSGLVMTAPSGASRTTLLLENNIHAASQGWTVSNDVQ 138 Score = 49.7 bits (117), Expect = 4e-06, Method: Composition-based stats. Identities = 31/165 (18%), Positives = 62/165 (37%), Gaps = 21/165 (12%) Query: 407 PYGNIQSRLELRKKLSCKPFKWYLENVYPELRVPDHQDIAFGALQQGTNCLDTLGHFADG 466 P G ++ L L + W + N D Q IA + CL G + Sbjct: 110 PSGASRTTLLLENNIHAASQGWTVSN--------DVQPIATLIVGYNEMCLQANGE--NN 159 Query: 467 VVGVYECHNAGGNQEWALTKEKSVKHM---DLCLTVVDRAPGSLIKLQGCRENDSRQKWE 523 V + +C Q+WAL +++++ LC+T LI ++ C+ ++ Sbjct: 160 NVWMEDCDVTSVQQQWALFDDRTIRVNNSRGLCVTSNGYVSKDLIVIRKCQGLATQ--RW 217 Query: 524 QIEGNSKLRHVGSNLCLDSR----TAKSGGLSVEVCGPALSQQWK 564 + + ++ S +D + + + + P +QQW+ Sbjct: 218 FFNSDGSVVNLKSTRVMDVKESDVSLQEVIIFPATGNP--NQQWR 260 Score = 35.5 bits (80), Expect = 0.073, Method: Composition-based stats. Identities = 18/98 (18%), Positives = 38/98 (38%), Gaps = 9/98 (9%) Query: 478 GNQEWALTKEKS------VKHMDLCLTVVDRAPGSLIKLQGCRENDSRQKWEQIEGNSKL 531 +Q W ++ + V + ++CL + + ++ C +Q+W + + Sbjct: 127 ASQGWTVSNDVQPIATLIVGYNEMCLQANG--ENNNVWMEDCDVTSVQQQWALFDDRTIR 184 Query: 532 RHVGSNLCLDSRTAKSGGLSV-EVCGPALSQQWKFTLN 568 + LC+ S S L V C +Q+W F + Sbjct: 185 VNNSRGLCVTSNGYVSKDLIVIRKCQGLATQRWFFNSD 222 >3CAH-A nrPDB Length = 258 Score = 103 bits (257), Expect = 2e-22, Method: Composition-based stats. Identities = 25/118 (21%), Positives = 45/118 (38%), Gaps = 4/118 (3%) Query: 456 CLDTLGH--FADGVVGVYECHNAGGNQEWALTKEKSVKHMDLCLTVVDRAPGSLIKLQGC 513 C+D + ++ C NQ W + +++ M C+T GS I + C Sbjct: 14 CVDVRNGYDTDGTPLQLWPCGTQR-NQRWTFDSDDTIRSMGKCMTANGLNNGSNIVIFNC 72 Query: 514 RENDSRQKWEQIEGNSKLRHVGSNLCLDSRTAKSGG-LSVEVCGPALSQQWKFTLNLQ 570 ++ + + + S L + + A S L +E A SQ W T N++ Sbjct: 73 STAAENAIKWEVPIDGSIINPSSGLVMTAPRAASRTILLLEDNIYAASQGWTVTNNVK 130 Score = 56.7 bits (135), Expect = 3e-08, Method: Composition-based stats. Identities = 24/115 (20%), Positives = 44/115 (38%), Gaps = 13/115 (11%) Query: 456 CLDTLGHFADGVVGVYECHNAGGNQEWALTKEKSVKHM---DLCLTVVDRAPGSLIKLQG 512 CL + G V + +C Q+WAL +++++ LC+T LI + Sbjct: 143 CLQSNGENNG--VWMEDCEATSLQQQWALYGDRTIRVNSTRGLCVTTNGYNSKDLIIILK 200 Query: 513 CRENDSRQKWEQIEGNSKLRHVGSNLCLDSRTAK----SGGLSVEVCGPALSQQW 563 C+ S+ + + + S L +D R + + P +QQW Sbjct: 201 CQGLPSQ--RWFFNSDGAIVNPKSRLVMDVRASNVSLREIIIFPATGNP--NQQW 251 Score = 39.7 bits (91), Expect = 0.004, Method: Composition-based stats. Identities = 23/121 (19%), Positives = 44/121 (36%), Gaps = 9/121 (7%) Query: 450 LQQGTNCLDTLGHFADGVVGVYECHNAGGNQE-WALTKEKSVK--HMDLCLTVVDRAPGS 506 ++ C+ G + ++ C A N W + + S+ L +T A + Sbjct: 49 IRSMGKCMTANGLNNGSNIVIFNCSTAAENAIKWEVPIDGSIINPSSGLVMTAPRAASRT 108 Query: 507 LIKLQGCRENDSRQKWEQIEGNSKLRHVGSN---LCLDSRTAKSGGLSVEVCGP-ALSQQ 562 ++ L+ + Q W + +CL S +G + +E C +L QQ Sbjct: 109 ILLLED-NIYAASQGWTVTNNVKPIVASIVGYKEMCLQSNGENNG-VWMEDCEATSLQQQ 166 Query: 563 W 563 W Sbjct: 167 W 167 Score = 33.6 bits (75), Expect = 0.25, Method: Composition-based stats. Identities = 23/132 (17%), Positives = 47/132 (35%), Gaps = 9/132 (6%) Query: 444 DIAFGALQQGTNCLDTLGHFADGVVGVYECHNAGGNQEWALTKE------KSVKHMDLCL 497 I + + + T A + + E + +Q W +T V + ++CL Sbjct: 85 PIDGSIINPSSGLVMTAPRAASRTILLLEDNIYAASQGWTVTNNVKPIVASIVGYKEMCL 144 Query: 498 TVVDRAPGSLIKLQGCRENDSRQKWEQIEGNSKLRHVGSNLCLDSRTAKSGGLSVEV-CG 556 G + ++ C +Q+W + + LC+ + S L + + C Sbjct: 145 QSNGENNG--VWMEDCEATSLQQQWALYGDRTIRVNSTRGLCVTTNGYNSKDLIIILKCQ 202 Query: 557 PALSQQWKFTLN 568 SQ+W F + Sbjct: 203 GLPSQRWFFNSD 214 >1GGP-B nrPDB Length = 254 Score = 92.5 bits (228), Expect = 4e-19, Method: Composition-based stats. Identities = 27/116 (23%), Positives = 45/116 (38%), Gaps = 4/116 (3%) Query: 456 CLDTLG-HFADGVVGVYECHNAGGNQEWALTKEKSVKHMDLCLTVVDRAPGSLIKLQGCR 514 C D G + + +C NQ W L +E +++ CLT A + + C Sbjct: 15 CADVNGEGQNGAAIILKKCAEND-NQLWTLKREATIRSNGGCLTTAA-AEQAKAGIYDCT 72 Query: 515 ENDSRQKWEQIEGNSKLRHVGSNLCLDSRTAKS-GGLSVEVCGPALSQQWKFTLNL 569 + + +I N + + S+L L S A S L V+ A +Q W+ Sbjct: 73 QATAELSAWEIADNGTIINPASSLVLSSGAANSLLDLGVQTNSYASAQGWRTGNET 128 Score = 42.4 bits (98), Expect = 6e-04, Method: Composition-based stats. Identities = 22/86 (25%), Positives = 37/86 (43%), Gaps = 7/86 (8%) Query: 465 DGVVGVY--ECHNAGGNQEWALTKEKSVKH---MDLCLTVVDRAPGSLIKLQGCRENDSR 519 +G ++ EC Q+WAL +KS++ D CLT A I L C + Sbjct: 147 NGPANLWMSECRAGKAEQQWALLTDKSIRSETNSDNCLTSAADAGPKTILLALC-SGPAS 205 Query: 520 QKWEQIEGNSKLRHVGSNLCLDSRTA 545 Q+W + + + + + +DS A Sbjct: 206 QRWV-FDDDGSILSLYDDKQMDSEGA 230 >5Y97-C nrPDB Length = 264 Score = 81.3 bits (199), Expect = 1e-15, Method: Composition-based stats. Identities = 25/119 (21%), Positives = 50/119 (42%), Gaps = 5/119 (4%) Query: 456 CLDTLGHFA--DGVVGVYECHNAGGNQEWALTKEKSVKHMDLCLTVVDRAPGSLIKLQGC 513 C+D G + +Y C NQ+W + +V+ + CL + G+L+ + C Sbjct: 19 CVDVAGALTSDGSRLILYPC-GQQVNQKWTFHSDGTVRSLGKCLATNNSKFGNLVVIYDC 77 Query: 514 RENDSRQKWEQIEGNSKLRHVG-SNLCLDS-RTAKSGGLSVEVCGPALSQQWKFTLNLQ 570 + + + + + +L L S + +S L++EV + SQ W+ +Q Sbjct: 78 SKLAAEDISWDVSVGGTIMNPNYEDLALTSNKATRSTNLTMEVNTYSASQGWRVGNYVQ 136 Score = 42.0 bits (97), Expect = 7e-04, Method: Composition-based stats. Identities = 22/114 (19%), Positives = 41/114 (35%), Gaps = 8/114 (7%) Query: 458 DTLGHFADGVVGVY--ECHNAGGNQEWALTKEKSVKHMD---LCLTVVDRAPGSLIKLQG 512 D DG ++ EC Q WAL + +++ D LC+T + + Sbjct: 147 DMCLEATDGNTNMWLEECVPNQREQSWALYSDGTIRVDDNRELCVTASSSTYDNWKVITI 206 Query: 513 CRENDSRQKWEQIEGNSKLRHVGSN-LCLDSRTAKSGGLSVEVCGP--ALSQQW 563 + S + + + G+ L +D + + + P L+QQW Sbjct: 207 LNCDGSNNQRWVFLADGSISTPGNQRLAMDVARSDVDLKKIILHRPHGDLNQQW 260 Score = 31.3 bits (69), Expect = 1.2, Method: Composition-based stats. Identities = 22/124 (17%), Positives = 43/124 (34%), Gaps = 10/124 (8%) Query: 448 GALQQGTNCLDTLGHFADGVVGVYECHNAGGNQE-WALTKEKSVK---HMDLCLTVVDRA 503 G ++ CL T +V +Y+C W ++ ++ + DL LT Sbjct: 52 GTVRSLGKCLATNNSKFGNLVVIYDCSKLAAEDISWDVSVGGTIMNPNYEDLALTSNKAT 111 Query: 504 PGSLIKLQGCRENDSRQKWEQIEGNSKLRHVGSNL---CLDSRTAKSGGLSVEVCGPALS 560 + + + + Q W + L CL++ + + +E C P Sbjct: 112 RSTNLTM-EVNTYSASQGWRVGNYVQPIIGSIVGLDDMCLEATDGNTN-MWLEECVPNQR 169 Query: 561 QQ-W 563 +Q W Sbjct: 170 EQSW 173 >3A22-A nrPDB Length = 614 Score = 81.0 bits (198), Expect = 1e-15, Method: Composition-based stats. Identities = 35/138 (25%), Positives = 56/138 (40%), Gaps = 11/138 (7%) Query: 437 LRVPDHQDIAFGALQQGTNCLDTLGHF--ADGVVGVYECHNAGGNQEWALTKEKS-VKHM 493 +R + A +Q C D + +++C N G NQ W T K V + Sbjct: 480 VRPLPGTNGALVTGKQSGRCADIYNNTITNGTQAELWDC-NGGPNQSWTYTSRKELVLYG 538 Query: 494 DLCLTVV--DRAPGSLIKLQGCRENDSRQKWEQIEGNSKLRHVGSNLCLDSR---TAKSG 548 + CL G+ + + C + QKW I + + +V + LCLD+ TA Sbjct: 539 NKCLDAYNLGTTNGTKVVIWDCN-GQANQKW-NINSDGTITNVNAGLCLDAYNAATANGT 596 Query: 549 GLSVEVCGPALSQQWKFT 566 L + CG +Q+W T Sbjct: 597 SLVLWSCGTGDNQKWTVT 614 >4ZFY-B nrPDB Length = 261 Score = 70.6 bits (171), Expect = 2e-12, Method: Composition-based stats. Identities = 25/115 (21%), Positives = 44/115 (38%), Gaps = 5/115 (4%) Query: 456 CLDTLGHFA--DGVVGVYECHNAGGNQEWALTKEKSVKHMDLCLTVVDRAPGSLIKLQGC 513 C+D G V +Y C NQ+W + +++ + CL + GS + + C Sbjct: 20 CVDVYGALTADGSRVILYPC-GQQQNQQWTFYPDNTIRSLGKCLATSALSSGSNVVITNC 78 Query: 514 RENDSRQKWEQIEGNSKLRHVGSNLCLDSRTAKSGG-LSVEVCGPALSQQWKFTL 567 W + + + + S+L L + A S L+ E A Q W+ Sbjct: 79 DYLRYDDGWM-VSSSGTMMNKSSHLVLTANAATSRTNLTGENNVFAAKQAWRIGN 132 Score = 40.5 bits (93), Expect = 0.002, Method: Composition-based stats. Identities = 17/89 (19%), Positives = 35/89 (39%), Gaps = 7/89 (7%) Query: 456 CLDTLGHFADGVVGVYECHNAGGNQEWALTKEKSVKHM---DLCLTVVDRAPGSLIKLQG 512 CL+ + D V + C Q WAL + +++ +LC++ + LI ++ Sbjct: 148 CLEATDN--DTNVWLESCVKNKTKQYWALYSDDTIRVNNNRNLCVSSSTDSSSKLIVIRR 205 Query: 513 CRENDSRQKWEQIEGNSKLRHVGSNLCLD 541 C + S + + + G +D Sbjct: 206 C--DGSINQRWVFTPQGTISNPGYEAVMD 232 Score = 36.7 bits (83), Expect = 0.029, Method: Composition-based stats. Identities = 23/78 (29%), Positives = 39/78 (50%), Gaps = 5/78 (6%) Query: 490 VKHMDLCLTVVDRAPGSLIKLQGCRENDSRQKWEQIEGNSKLRHVGSNLCLDSRTAKSGG 549 ++HM CL D + + L+ C +N ++Q W ++ + NLC+ S T S Sbjct: 144 LRHM--CLEATDN--DTNVWLESCVKNKTKQYWALYSDDTIRVNNNRNLCVSSSTDSSSK 199 Query: 550 LSV-EVCGPALSQQWKFT 566 L V C +++Q+W FT Sbjct: 200 LIVIRRCDGSINQRWVFT 217 >1IT0-A nrPDB Length = 436 Score = 69.4 bits (168), Expect = 4e-12, Method: Composition-based stats. Identities = 37/135 (27%), Positives = 58/135 (42%), Gaps = 10/135 (7%) Query: 438 RVPDHQDIAFGALQQGTNCLDT-LGHFADGV-VGVYECHNAGGNQEWALTKEKSVK-HMD 494 P + G CLD DG V +Y+CH+A NQ+W T ++ + D Sbjct: 306 TPPPSGGGQIKGVGSG-RCLDVPNASTTDGTQVQLYDCHSAT-NQQWTYTDAGELRVYGD 363 Query: 495 LCLTVVDRAPGSLIKLQGCRENDSRQKWEQIEGNSKLRHVGSNLCLDSR---TAKSGGLS 551 CL G+ +++ C D QKW ++ + + V S LCLD+ TA + Sbjct: 364 KCLDAAGTGNGTKVQIYSCWGGD-NQKW-RLNSDGSIVGVQSGLCLDAVGGGTANGTLIQ 421 Query: 552 VEVCGPALSQQWKFT 566 + C +Q+W T Sbjct: 422 LYSCSNGSNQRWTRT 436 >2Z87-A nrPDB Length = 624 Score = 68.6 bits (166), Expect = 6e-12, Method: Composition-based stats. Identities = 46/229 (20%), Positives = 87/229 (37%), Gaps = 29/229 (12%) Query: 139 SVVITFHNEARSALLRTVVSVLKKSPPHLIKEIILVDDYSNDPEDGALLGKIEKVRVLRN 198 S+VI +N A+ L T+ + + E+I+ DD S ++ + E + ++ Sbjct: 95 SIVIPTYNRAK-ILAITLACLCNQK-TIYDYEVIVADDGS-KENIEEIVREFESLLNIKY 151 Query: 199 DRRE----GLMRSRVRGADAAQAKVLTFLDSHCECNEHWLEPLLERVA-EDRTRVVSP-- 251 R++ L R G AA+ + LD N W++ +E +A +D ++ P Sbjct: 152 VRQKDYGYQLCAVRNLGLRAAKYNYVAILDCDMAPNPLWVQSYMELLAVDDNVALIGPRK 211 Query: 252 IIDVINMDNFQYVGASA------------DLKGGFDWNLVFKWDYMTPEQRRSRQGNPVA 299 ID ++ + + G + N W + + + Sbjct: 212 YIDTSKHTYLDFLSQKSLINEIPEIITNNQVAGKVEQNKSVDW-----RIEHFKNTDNLR 266 Query: 300 PIKTPM--IAGGLFVMDKFYFEELGKYDMMMDVWGGENLEISFRVWQCG 346 TP +GG K + G +D WGGE+ E +R+++ G Sbjct: 267 LCNTPFRFFSGGNVAFAKKWLFRAGWFDEEFTHWGGEDNEFGYRLYREG 315 >3WN1-A nrPDB Length = 438 Score = 66.7 bits (161), Expect = 3e-11, Method: Composition-based stats. Identities = 34/126 (26%), Positives = 59/126 (46%), Gaps = 13/126 (10%) Query: 448 GALQQ--GTNCLDTLGHFA--DGVVGVYECHNAGGNQEWALTKEKSVK-HMDLCLTVVDR 502 GAL+ CLD LG ++ +Y+C G NQ+W T + + D CL V Sbjct: 4 GALRGAGSNRCLDVLGGSQDDGALLQLYDCW-GGTNQQWTSTDTGRLTVYGDKCLDVPGH 62 Query: 503 --APGSLIKLQGCRENDSRQKWEQIEGNSKLRHVGSNLCLDSR-TAKSGGLSVE--VCGP 557 APG+ +++ C ++Q ++ + + V S LCL++ + G +V+ C Sbjct: 63 ATAPGTRVQIWSCSGGANQQ--WRVNSDGTVVGVESGLCLEAAGAGTANGTAVQLWTCNG 120 Query: 558 ALSQQW 563 +Q+W Sbjct: 121 GGNQKW 126 >2Z49-A nrPDB Length = 432 Score = 58.6 bits (140), Expect = 7e-09, Method: Composition-based stats. Identities = 28/119 (23%), Positives = 47/119 (39%), Gaps = 10/119 (8%) Query: 453 GTNCLDTLGHFADGVVGVYECHNAGGNQEWALTKEKSVKHM-------DLCLTVVDRAPG 505 CLD G G +GVY+C N + ++ + + DLCL V Sbjct: 116 SGKCLDIEGSDGTGDIGVYDCQNLDDQYFYVRSRGPELFYGRLRNEKSDLCLDVEGSDGK 175 Query: 506 SLIKLQGCRENDSRQKWEQIEGNSKLRHVGSNLCLDSR-TAKSGGLSVEVCGPALSQQW 563 + + C +N +W + N ++ + S +CLD + SG + + C Q W Sbjct: 176 GNVLMYSCEDNL--DQWFRYYENGEIVNAKSGMCLDVEGSDGSGNVGIYRCDDLRDQMW 232 Score = 45.1 bits (105), Expect = 9e-05, Method: Composition-based stats. Identities = 25/130 (19%), Positives = 48/130 (36%), Gaps = 22/130 (16%) Query: 444 DIAFGALQQ--GTNCLDTLGHFADGVVGVYECHNAGGNQEWALTKEKSVKH--MDLCLTV 499 + G L+ C+D +G+ G + Y+C Q + + ++++ + C T Sbjct: 7 PLDIGELRSFKSKQCVDIVGNQGSGNIATYDCDGLSDQQI-IICGDGTIRNEARNYCFT- 64 Query: 500 VDRAPGSLIKLQGC---RENDSRQKWEQ-----IEGNS-------KLRHVGSNLCLDSRT 544 D + + + C E S Q+W Q N ++ ++ S CLD Sbjct: 65 PDGSGNANVMSSPCTLYPEIPSSQRWRQGRRKTFTDNGGIEQVATEIINLASGKCLDIE- 123 Query: 545 AKSGGLSVEV 554 G + V Sbjct: 124 GSDGTGDIGV 133 Score = 38.6 bits (88), Expect = 0.007, Method: Composition-based stats. Identities = 26/147 (17%), Positives = 48/147 (32%), Gaps = 28/147 (19%) Query: 448 GALQQGT--NCL--DTLGHFA--DGVVGVYECHNAGGNQEWALTKEKSVKHMD------- 494 G ++ C D G+ +Y +Q W + K+ Sbjct: 52 GTIRNEARNYCFTPDGSGNANVMSSPCTLYP--EIPSSQRWRQGRRKTFTDNGGIEQVAT 109 Query: 495 --------LCLTVVDRAPGSLIKLQGCRENDSRQKWEQIEGN----SKLRHVGSNLCLDS 542 CL + I + C+ D + + + G +LR+ S+LCLD Sbjct: 110 EIINLASGKCLDIEGSDGTGDIGVYDCQNLDDQYFYVRSRGPELFYGRLRNEKSDLCLDV 169 Query: 543 R-TAKSGGLSVEVCGPALSQQWKFTLN 568 + G + + C L Q +++ N Sbjct: 170 EGSDGKGNVLMYSCEDNLDQWFRYYEN 196 >5TZ8-A nrPDB Length = 572 Score = 57.1 bits (136), Expect = 2e-08, Method: Composition-based stats. Identities = 28/127 (22%), Positives = 53/127 (41%), Gaps = 12/127 (9%) Query: 139 SVVITFHNEARSALLRTVVSVLKKSPPHLIKEIILVDDYSNDPEDGALLGKIEKVRVLRN 198 SV++ +N + + + S+ K+ P E+++VDD S D L +EK R N Sbjct: 4 SVIVPTYNSEK-YITELLNSLAKQDFPKTEFEVVVVDDCSTD----QTLQIVEKYRNKLN 58 Query: 199 DRREGLM-------RSRVRGADAAQAKVLTFLDSHCECNEHWLEPLLERVAEDRTRVVSP 251 + L + R A+ + + F+DS N+ L+ + E + V+ Sbjct: 59 LKVSQLETNSGGPGKPRNVALKQAEGEFVLFVDSDDYINKETLKDAAAFIDEHHSDVLLI 118 Query: 252 IIDVINM 258 + +N Sbjct: 119 KMKGVNG 125 >5MLZ-A nrPDB Length = 374 Score = 54.8 bits (130), Expect = 1e-07, Method: Composition-based stats. Identities = 29/109 (26%), Positives = 50/109 (45%), Gaps = 6/109 (5%) Query: 137 ATSVVITFHNEARSALLRTVVSVLKKSPPHLIKEIILVDDYSND---PEDGALLGKIEKV 193 SV+I +NE + L + S + + L EI++VDD S D + L K V Sbjct: 24 KVSVIIPTYNEREN--LEELFSRIDNALQGLNYEIVVVDDDSPDRTWEKAQELSSKYP-V 80 Query: 194 RVLRNDRREGLMRSRVRGADAAQAKVLTFLDSHCECNEHWLEPLLERVA 242 +V+R + +GL + +RG A V +D+ + + L+E + Sbjct: 81 KVIRRTKEKGLSSAVIRGFKEASGDVFVVMDADLQHPPEVIPKLIEAIK 129 >5EKE-A nrPDB Length = 341 Score = 41.3 bits (95), Expect = 0.001, Method: Composition-based stats. Identities = 24/93 (25%), Positives = 42/93 (45%), Gaps = 7/93 (7%) Query: 139 SVVITFHNEARS--ALLRTVVSVLKKSPPHLIKEIILVDDYSNDPEDGALLGKIEK---V 193 S+VI +NE + L ++ VL +P + EII V+D S D L+ + + Sbjct: 29 SIVIPMYNEEDNLEHLFARLLEVL--TPLKITYEIICVNDGSKDKTLKQLIDCYQSNRQI 86 Query: 194 RVLRNDRREGLMRSRVRGADAAQAKVLTFLDSH 226 +++ R G + G D AQ + +D+ Sbjct: 87 KIVNLSRNFGKEIALSAGIDYAQGNAVIPIDAD 119 >3L7K-A nrPDB Length = 729 Score = 41.3 bits (95), Expect = 0.001, Method: Composition-based stats. Identities = 22/123 (17%), Positives = 52/123 (42%), Gaps = 10/123 (8%) Query: 135 LPATSVVITFHNEARSALLRTVVSVLKKSPPHLIKEIILVDDYSNDPEDG---ALLGKIE 191 + ++++T++N + + S+ ++ +I+V+D S D + + Sbjct: 1 MNKLTIIVTYYNAE-EYITGCLESIKQQ--RTQDFNLIIVNDGSTDQSKKLMDEAIKDYD 57 Query: 192 K-VRVLRNDRREGLMRSRVRGADAAQAKVLTFLDSHCECNEHWLEPLLERVAEDRTR-VV 249 K +R + D G +R + + FLD+ E + + LE+ + T ++ Sbjct: 58 KNIRFIDLDENSGHAHARNIALEEVETPYFMFLDADDELASYAITFYLEKF--NNTDGLI 115 Query: 250 SPI 252 +PI Sbjct: 116 API 118 >5OCR-A nrPDB Length = 286 Score = 34.0 bits (76), Expect = 0.17, Method: Composition-based stats. Identities = 32/153 (20%), Positives = 55/153 (35%), Gaps = 27/153 (17%) Query: 168 IKEIILVDDYSNDPEDGALL--GKIEKVRVLRNDRREGLMRSRVRGADAAQAKVLTFLDS 225 I E+ + + +N P+ G G + + E ++++GAD + Sbjct: 67 IAELTMRHNANNTPDGGTYFTSGIFKSYQKFTYGYFE----AKIQGADIGEG-------- 114 Query: 226 HCECNEHWLEPLLERVAEDRTRVVSPIIDVINMDNFQYVGASADLKGGFDWNL------- 278 C WL + + V S IDV+ + F + D D NL Sbjct: 115 --VCPSFWLYSDFDYSVANGETVYSE-IDVVELQQFDWYEGHQDDIYDMDLNLHAVVKEN 171 Query: 279 ---VFKWDYMTPEQRRSRQGNPVAPIKTPMIAG 308 V+K M P+++ ++ P P K I G Sbjct: 172 GQGVWKRPKMYPQEQLNKWRAPWDPSKDFHIYG 204 >5KY2-A nrPDB Length = 355 Score = 32.4 bits (72), Expect = 0.58, Method: Composition-based stats. Identities = 23/104 (22%), Positives = 36/104 (34%), Gaps = 13/104 (12%) Query: 343 WQCGGSLEIIPC-SRVGHVFRKQHPYTFPGGSGTVFARNTRRAAEVWMDEYKNFYYAAVP 401 W G L PC R G+ Q + F G N A W+ EY++ P Sbjct: 5 WDLAGYLLYCPCMGRFGN----QADH-FLGSLAFAKLLNRTLAVPPWI-EYQHH----KP 54 Query: 402 SAR--NVPYGNIQSRLELRKKLSCKPFKWYLENVYPELRVPDHQ 443 +V Y L+ + ++EN+ P P+ + Sbjct: 55 PFTNLHVSYQKYFKLEPLQAYHRVVSLEDFMENLAPSHWPPEKR 98 >3OOQ-A nrPDB Length = 396 Score = 32.0 bits (71), Expect = 0.72, Method: Composition-based stats. Identities = 30/127 (23%), Positives = 47/127 (37%), Gaps = 22/127 (17%) Query: 283 DYMTPEQRRSRQGNPVAPIKTPMIAGGLFVMDKFYFEELGKYDMMMDVWGGENLEISFR- 341 D +TP + NP P +AGG+ + G + + GG+ I FR Sbjct: 85 DPVTPHVKALDGFNPQDPAIERALAGGVTSV----MIVPGSANPV----GGQGSVIKFRS 136 Query: 342 --VWQC------GGSLEIIPCSRVGHVFRKQHPYTFPGGSGTVF-----ARNTRRAAEVW 388 V +C G + + + RKQ P T G +G + +N + E+ Sbjct: 137 IIVEECIVKDPAGLKMAFGENPKRVYGERKQTPSTRMGTAGVIRDYFTKVKNYMKKKELA 196 Query: 389 MDEYKNF 395 E K F Sbjct: 197 QKEGKEF 203 >2B4T-O nrPDB Length = 345 Score = 31.3 bits (69), Expect = 1.4, Method: Composition-based stats. Identities = 17/69 (24%), Positives = 28/69 (40%), Gaps = 1/69 (1%) Query: 209 VRGADAAQAKVLTFLDSHCECNEHWLEPLLERVAEDRTRVVSPIIDVINMDNFQYVGASA 268 V G + Q + S+ C + L PL +V DR +V ++ ++ + Sbjct: 141 VMGINHHQYDTKQLIVSNASCTTNCLAPL-AKVINDRFGIVEGLMTTVHASTANQLVVDG 199 Query: 269 DLKGGFDWN 277 KGG DW Sbjct: 200 PSKGGKDWR 208 >5AJ4-Ba nrPDB Length = 423 Score = 30.9 bits (68), Expect = 1.5, Method: Composition-based stats. Identities = 8/37 (21%), Positives = 14/37 (37%) Query: 265 GASADLKGGFDWNLVFKWDYMTPEQRRSRQGNPVAPI 301 G A +G ++W + P R + + PI Sbjct: 22 GCGAPRRGAYEWGVRSTRKPEPPPLDRVYEIPGLEPI 58 >3STH-A nrPDB Length = 361 Score = 30.1 bits (66), Expect = 2.4, Method: Composition-based stats. Identities = 12/53 (22%), Positives = 23/53 (43%), Gaps = 1/53 (1%) Query: 225 SHCECNEHWLEPLLERVAEDRTRVVSPIIDVINMDNFQYVGASADLKGGFDWN 277 S+ C + L PL ++ D+ +V ++ ++ + KGG DW Sbjct: 169 SNASCTTNCLAPL-AKIVHDKFGIVEGLMTTVHAMTANQLTVDGPSKGGKDWR 220 >3N42-F nrPDB Length = 473 Score = 29.3 bits (64), Expect = 5.1, Method: Composition-based stats. Identities = 15/69 (21%), Positives = 26/69 (37%), Gaps = 5/69 (7%) Query: 328 MDVWGGENLEISFRVWQCGGSLEIIPCSRVGHVFRKQHPYT-----FPGGSGTVFARNTR 382 ++V G L+ISF + CS H + HP +P T+ ++ Sbjct: 366 IEVEGNSQLQISFSTALASAEFRVQVCSTQVHCAAECHPPKDHIVNYPASHTTLGVQDIS 425 Query: 383 RAAEVWMDE 391 A W+ + Sbjct: 426 ATAMSWVQK 434 >2XFC-A nrPDB Length = 439 Score = 29.3 bits (64), Expect = 5.1, Method: Composition-based stats. Identities = 15/69 (21%), Positives = 26/69 (37%), Gaps = 5/69 (7%) Query: 328 MDVWGGENLEISFRVWQCGGSLEIIPCSRVGHVFRKQHPYT-----FPGGSGTVFARNTR 382 ++V G L+ISF + CS H + HP +P T+ ++ Sbjct: 344 IEVEGNSQLQISFSTALASAEFRVQVCSTQVHCAAECHPPKDHIVNYPASHTTLGVQDIS 403 Query: 383 RAAEVWMDE 391 A W+ + Sbjct: 404 ATAMSWVQK 412 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.307 0.127 0.359 Lambda K H 0.267 0.0396 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 22,169,027 Number of Sequences: 36641 Number of extensions: 908830 Number of successful extensions: 2580 Number of sequences better than 10.0: 37 Number of HSP's better than 10.0 without gapping: 37 Number of HSP's successfully gapped in prelim test: 27 Number of HSP's that attempted gapping in prelim test: 2363 Number of HSP's gapped (non-prelim): 133 length of query: 571 length of database: 10,336,785 effective HSP length: 102 effective length of query: 469 effective length of database: 6,599,403 effective search space: 3095120007 effective search space used: 3095120007 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.1 bits) S2: 62 (28.5 bits)