BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q10429 (875 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 5OQR-A nrPDB 1571 0.0 5OQP-A nrPDB 334 9e-92 6IGX-B nrPDB 214 1e-55 2OT8-A nrPDB 33 0.46 3W9R-A nrPDB 31 2.2 5WTZ-A nrPDB 31 2.7 3WCG-A nrPDB 30 4.2 2QVP-A nrPDB 30 5.1 >5OQR-A nrPDB Length = 788 Score = 1571 bits (4068), Expect = 0.0, Method: Compositional matrix adjust. Identities = 788/823 (95%), Positives = 788/823 (95%), Gaps = 35/823 (4%) Query: 1 MSCIQIISSSQTSIAGHRKLCNKLFTLRTQEGFETDILRALNIILTVKKGNSNADRVLRF 60 MSCIQIISSSQTSIAGHRKLCNKLFTLRTQEGFETDILRALNIILTVKKGNSNADRVLRF Sbjct: 1 MSCIQIISSSQTSIAGHRKLCNKLFTLRTQEGFETDILRALNIILTVKKGNSNADRVLRF 60 Query: 61 LVTFVNYLQQKDPEIDIVQPILKHILRGLDAKDKTVRYRCCQIIARVVNCVKEIDDDLYN 120 LVTFVNYLQQKDPEIDIVQPILKHILRGLDAKDKTVRYRCCQIIARVVNCVKEIDDDLYN Sbjct: 61 LVTFVNYLQQKDPEIDIVQPILKHILRGLDAKDKTVRYRCCQIIARVVNCVKEIDDDLYN 120 Query: 121 TLKEKLLSRVLDRESIVRLEAVVALSRLQEDTGDEENDVRNILLFLLQNDPSSEVRRSVL 180 TLKEKLLSRVLDRESIVRLEAVVALSRLQEDTGDEENDVRNILLFLLQNDPSSEVRRSVL Sbjct: 121 TLKEKLLSRVLDRESIVRLEAVVALSRLQEDTGDEENDVRNILLFLLQNDPSSEVRRSVL 180 Query: 181 LNIEVSNSTLPFILERARDVDAANRKCVYARVLPKIGDFRYLSIKKRVRILKWGLNDRDE 240 LNIEVSNSTLPFILERARDVDAANRKCVYARVLPKIGDFRYLSIKKRVRILKWGLNDRDE Sbjct: 181 LNIEVSNSTLPFILERARDVDAANRKCVYARVLPKIGDFRYLSIKKRVRILKWGLNDRDE 240 Query: 241 SVEKAAADMLAYQWIENADNNLLELLERLDVSNNSDVAVLAIKKFFDVRVDSLSQLEFPE 300 SVEKAAADMLAYQWIENADNNLLELLERLDVSNNSDVAVLAIKKFFDVRVDSLSQLEFPE Sbjct: 241 SVEKAAADMLAYQWIENADNNLLELLERLDVSNNSDVAVLAIKKFFDVRVDSLSQLEFPE 300 Query: 301 QFWLELTAESSLLARTFNEICIEKNYTDLLDKMPEVVQLTYYIERQYVSLRDKSSYDESC 360 QFWLELTAESSLLARTFNEICIEKNYTDLLDKMPEVVQLTYYIERQYVSLRDKSSYDESC Sbjct: 301 QFWLELTAESSLLARTFNEICIEKNYTDLLDKMPEVVQLTYYIERQYVSLRDKSSYDESC 360 Query: 361 FIIEQLLYIGLSQDMVDEIGRRKLLKSLTNSLSTMALPDSLISLHIELLRKLCSSENDFC 420 FIIEQLLYIGLSQDMVDEIGRRKLLKSLTNSLSTMALPDSLISLHIELLRKLCSSENDFC Sbjct: 361 FIIEQLLYIGLSQDMVDEIGRRKLLKSLTNSLSTMALPDSLISLHIELLRKLCSSENDFC 420 Query: 421 SLLVEIITEVFEQGHSQNQTEEQGNSNAPELNKNDYEGEEITVSQKSPSPSLPPNELNEP 480 SLLVEIITEVFEQGHSQN PNELNEP Sbjct: 421 SLLVEIITEVFEQGHSQN-----------------------------------PNELNEP 445 Query: 481 EPDDMDGYKEAFNELRCLSYVQCLFENITSSLNENLYMVDMLKTLIIPAVRSHDLPIREK 540 EPDDMDGYKEAFNELRCLSYVQCLFENITSSLNENLYMVDMLKTLIIPAVRSHDLPIREK Sbjct: 446 EPDDMDGYKEAFNELRCLSYVQCLFENITSSLNENLYMVDMLKTLIIPAVRSHDLPIREK 505 Query: 541 GLECLSLVCLLNADLAFENVPLYLHCYEKGSVVLKCTAIRTLTDMLIQHGKAKFTEYEDA 600 GLECLSLVCLLNADLAFENVPLYLHCYEKGSVVLKCTAIRTLTDMLIQHGKAKFTEYEDA Sbjct: 506 GLECLSLVCLLNADLAFENVPLYLHCYEKGSVVLKCTAIRTLTDMLIQHGKAKFTEYEDA 565 Query: 601 ISSILFEALGEFENAELQTLGAEAIAKLLVILHYRDELFLKPLIIQYFEPNTVDNHALRQ 660 ISSILFEALGEFENAELQTLGAEAIAKLLVILHYRDELFLKPLIIQYFEPNTVDNHALRQ Sbjct: 566 ISSILFEALGEFENAELQTLGAEAIAKLLVILHYRDELFLKPLIIQYFEPNTVDNHALRQ 625 Query: 661 VLGYFFPVYAFGAHENQWRIATIFCDALLSLLEIYRDLDEDDVQLSIGHIAQQMLDWTDN 720 VLGYFFPVYAFGAHENQWRIATIFCDALLSLLEIYRDLDEDDVQLSIGHIAQQMLDWTDN Sbjct: 626 VLGYFFPVYAFGAHENQWRIATIFCDALLSLLEIYRDLDEDDVQLSIGHIAQQMLDWTDN 685 Query: 721 EKLYERKTQTGDDYIALNHNVHLHLANMIFESLPNASEGKERKFMISLLGKLKIPTDLPS 780 EKLYERKTQTGDDYIALNHNVHLHLANMIFESLPNASEGKERKFMISLLGKLKIPTDLPS Sbjct: 686 EKLYERKTQTGDDYIALNHNVHLHLANMIFESLPNASEGKERKFMISLLGKLKIPTDLPS 745 Query: 781 SDYQRTKRKLETYESHGFTMDSTSLSILAKFERMLLQNEEARS 823 SDYQRTKRKLETYESHGFTMDSTSLSILAKFERMLLQNEEARS Sbjct: 746 SDYQRTKRKLETYESHGFTMDSTSLSILAKFERMLLQNEEARS 788 >5OQP-A nrPDB Length = 869 Score = 334 bits (857), Expect = 9e-92, Method: Compositional matrix adjust. Identities = 244/794 (30%), Positives = 401/794 (50%), Gaps = 97/794 (12%) Query: 2 SCIQIISSSQTSIAGHRK---LCNKLFTLRTQEGFETDIL----RALNIILTVKKGNSNA 54 S ++ +Q S AGHRK + K+ + ++G+E + + IL +KK N Sbjct: 12 SVAEVFQKAQGSYAGHRKHIAVLKKIQSKAVEQGYEDAFNFWFDKLVTKILPLKK-NEII 70 Query: 55 DRVLRFLVTFV-------------NYLQQKDPE---IDIVQPILKHILRGLDAKDKTVRY 98 DR+++ + F+ NY D E V ++H+LRG+++ DK VR+ Sbjct: 71 DRIVKLVAAFIASLERELILAKKQNYKLTNDEEGIFSRFVDQFIRHVLRGVESPDKNVRF 130 Query: 99 RCCQIIARVVNCVKEIDDDLYNTLKEKLLSRVLDRESIVRLEAVVALSRLQED------- 151 R Q++A +++ + EID+ L+N L L R+ DRE VR++AV L++ Q++ Sbjct: 131 RVLQLLAVIMDNIGEIDESLFNLLILSLNKRIYDREPTVRIQAVFCLTKFQDEEQTEHLT 190 Query: 152 --TGDEEN-DVRNILLFLLQNDPSSEVRRSVLLNIEVSNSTLPFILERARDVDAANRKCV 208 + +EEN + L+ +QNDPS+EVRR+ +LN+ N+T P+ILERARDV+ NR+ V Sbjct: 191 ELSDNEENFEATRTLVASIQNDPSAEVRRAAMLNLINDNNTRPYILERARDVNIVNRRLV 250 Query: 209 YARVLPKIGDFRYLSIKKRV--RILKWGLNDRDESVEKAAADMLAYQWIENADNNLLELL 266 Y+R+L +G + I+ + ++++WGL DR+ SV A ++A+ W+ D +L+ELL Sbjct: 251 YSRILKSMGRKCFDDIEPHIFDQLIEWGLEDRELSVRNACKRLIAHDWLNALDGDLIELL 310 Query: 267 ERLDVSNNSDVAVLAIKKFFDVRVDSLSQLEFPEQFWLELTAESSLLARTFNEICIEKNY 326 E+LDVS +S V V AI+ F R D LS+++FP W + T E + L R C++ N Sbjct: 311 EKLDVSRSS-VCVKAIEALFQSRPDILSKIKFP-SIWKDFTVEIAFLFRAIYLYCLDNNI 368 Query: 327 TDLLDK-MPEVVQLT----YYIERQY----VSLRDKSSYDESC--FIIEQLLYIGLSQDM 375 T++L++ PE +L+ +YI +Y +S +S +D + FIIEQL D Sbjct: 369 TEMLEENFPEASKLSEHLNHYILLRYHHNDISNDSQSHFDYNTLEFIIEQLSIAAERYDY 428 Query: 376 VDEIGRRKLLKSLTNSLSTMALPDSLISLHIELLRKLCSSENDFCSLLVEIITEVFEQGH 435 DE+GRR +L + N L+ L + LI + I +++ L +E DF ++ +EII ++ + Sbjct: 429 SDEVGRRSMLTVVRNMLALTTLSEPLIKIGIRVMKSLSINEKDFVTMAIEIINDIRDDDI 488 Query: 436 SQNQTEEQGNSNAPELNKNDYEGEEITVSQKSPSPSLPPNELNEPEPDDMDGYKEAFNEL 495 + ++E +N P + E T+ + Sbjct: 489 EKQESESDIINNLPP----EKEASSATI-------------------------------V 513 Query: 496 RCLSYVQCLFENITSSLNENLYMVDMLKTLIIPAVRSHDLPIREKGLECLSLVCLLNADL 555 CL+ + E + + L EN+ + ++ TLI PAVR+ IRE G++ L L CLL+ L Sbjct: 514 LCLTRSSYMLELVNTPLTENILIASLMDTLITPAVRNTAPNIRELGVKNLGLCCLLDVKL 573 Query: 556 AFENVPLYLHCYEKGSVVLKCTAIRTLTDMLIQHGKAKFTEYEDAISS-----ILFEALG 610 A +N+ + C KG+ LK A++ + D+ HG + E + S I ++ L Sbjct: 574 AIDNMYILGMCVSKGNASLKYIALQVIVDIFSVHGNT-VVDGEGKVDSISLHKIFYKVLK 632 Query: 611 EFENAELQTLGAEAIAKLLVILHYRDELFLKPLIIQYFEPNTVDNHALRQVLGYFFPVYA 670 E Q + AE + KL + + D+ + L++ YF P N AL Q + PVY Sbjct: 633 NNGLPECQVIAAEGLCKLFLADVFTDDDLFETLVLSYFSPINSSNEALVQAFAFCIPVYC 692 Query: 671 FGAHENQWRIATIFCDALLSLLEIYRDLD-------EDDVQLSIGHIAQQMLDWTDNEKL 723 F +Q R++ D LL L ++ DL + + L I QQ+L WTD L Sbjct: 693 FSHPAHQQRMSRTAADILLRLCVLWDDLQSSVIPEVDREAMLKPNIIFQQLLFWTDPRNL 752 Query: 724 YERKTQTGDDYIAL 737 + T D + L Sbjct: 753 VNQTGSTKKDTVQL 766 >6IGX-B nrPDB Length = 839 Score = 214 bits (545), Expect = 1e-55, Method: Compositional matrix adjust. Identities = 222/793 (27%), Positives = 356/793 (44%), Gaps = 129/793 (16%) Query: 26 TLRTQEGFETDILRALNIILTVKKGNSNADRVLRFLVTFVNYLQQKDPEI-------DIV 78 T+ + F + + L ++ V K +RV+ F FV Q D E ++ Sbjct: 51 TMDDKTVFHEEFIHYLKYVMVVYKREPAVERVIEFAAKFVTSFHQSDMEDDEEEEDGGLL 110 Query: 79 QPILKHILRGLDAKDKTVRYRCCQIIARVVNCVKE---IDDDLYNTLKEKLLSRVLDRES 135 + +L+ +A VR+R C +I +++ + E IDDD+++ + + +L R+ D+ Sbjct: 111 NYLFTFLLKSHEANSNAVRFRVCLLINKLLGSMPENAQIDDDVFDKINKAMLIRLKDKIP 170 Query: 136 IVRLEAVVALSRLQEDTGDEENDVRNILLFLLQNDPSSEVRRSVLLNIEVSNSTLPFILE 195 VR++AV+ALSRLQ D D+E V N L++ND + EVRR+VL I S TLP I+ Sbjct: 171 NVRIQAVLALSRLQ-DPKDDECPVVNAYATLIENDSNPEVRRAVLSCIAPSAKTLPKIVG 229 Query: 196 RARDVDAANRKCVYARVLPKIGDFRYLSIKKRVRILKWGLNDRDESVEKAAADMLAYQWI 255 R +DV A RK Y +VL + R +SI +RV +L+ GLNDR ++V++A L W+ Sbjct: 230 RTKDVKEAVRKLAY-QVLAEKVHMRAMSIAQRVMLLQQGLNDRSDAVKQAMQKHLLQGWL 288 Query: 256 ENADNNLLELLERLDVSNNSDVAVLAIKKFFDVRVDSLSQLE-----------FPEQFWL 304 ++ N+LELL RLDV N+S+VAV + F + LS+L P + Sbjct: 289 RFSEGNILELLHRLDVENSSEVAVSVLNALFS--ITPLSELVGLCKNNDGRKLIPVE--- 343 Query: 305 ELTAESSLLARTFNEICIEKN--YTDLLDK-MPEVVQLTYYIERQYVSL-------RDKS 354 LT E +L E K + L++ +PE V Y+ S+ R Sbjct: 344 TLTPEIALYWCALCEYLKSKGDEGEEFLEQILPEPVVYADYLLSYIQSIPVVNEEHRGDF 403 Query: 355 SYDESC----FIIEQLLYIGLSQDMVDEIGRRKLLKSLTNSLSTMALPDSLISLHIELLR 410 SY + FI +QL+ I S D +E GR+KLL L L +P SL+S +E L Sbjct: 404 SYIGNLMTKEFIGQQLILIIKSLDTSEEGGRKKLLAVLQEILILPTIPISLVSFLVERLL 463 Query: 411 KLCSSENDFCSLLVEIITEVFEQGHSQNQTEEQGNSNAPELNKNDYEGEEITVSQKSPSP 470 + +N ++ EII+E+ AP +TV Sbjct: 464 HIIIDDNKRTQIVTEIISEI----------------RAP----------IVTV------- 490 Query: 471 SLPPNELNEPEPDDMDGYKEAFNELRCLSYVQCLFENITSSLNENLYMVDMLKTLIIPAV 530 G E +CL L + ++ S + M ++++LI+P + Sbjct: 491 ----------------GVAETLQ--KCLILCYELLKQMSISTGLSATMNGIIESLILPGI 532 Query: 531 RSHDLPIREKGLECLSLVCLLNADLAFENVPLYLHCYEKGSVVLKCTAIRTLTDMLIQHG 590 S +R + CL L N D A ++ L L + V +K +A++ + D L+ G Sbjct: 533 ISIHPVVRNLAVLCLGCCGLQNQDFARKHFVLLLQVLQIDDVTIKISALKAIFDQLMTFG 592 Query: 591 KAKF------------TEY------------EDAISSILFEALGEF---ENAELQTLGAE 623 F TE E A + + + L +F E +EL+T AE Sbjct: 593 IEPFKTKKIKTLHCEGTEINSDDEQESKEVEETATAKNVLKLLSDFLDSEVSELRTGAAE 652 Query: 624 AIAKLLVILHYRDELFLKPLIIQYFEPNTVDNHALRQVLGYFFPVYAFGAHENQWRIATI 683 +AKL+ L LI+ ++ P T ++ LR LG FFPV+A+ + NQ Sbjct: 653 GLAKLMFSGLLVSSRILSRLILLWYNPVTEEDVQLRHCLGVFFPVFAYASRTNQ----EC 708 Query: 684 FCDALLSLLEIYRDLDEDD--VQLSIGHIAQQMLDWTDNEKLYERKTQTGDDYIAL--NH 739 F +A L L+ + ++ I ++A+ ++D T L + +T DY AL + Sbjct: 709 FEEAFLPTLQTLANAPASSPLAEIDITNVAELLVDLTRPSGL-NPQAKTSQDYQALTVHD 767 Query: 740 NVHLHLANMIFES 752 N+ + + N I S Sbjct: 768 NLAMKICNEILTS 780 >2OT8-A nrPDB Length = 852 Score = 33.5 bits (75), Expect = 0.46, Method: Compositional matrix adjust. Identities = 22/76 (28%), Positives = 36/76 (47%), Gaps = 1/76 (1%) Query: 81 ILKHILRGLDAKDKTVRYRCCQIIARVVNCVKEIDDDLY-NTLKEKLLSRVLDRESIVRL 139 ++ H+++ L K VR C ++R + V D Y L +LL R+LD V+ Sbjct: 401 LIPHLIQCLSDKKALVRSITCWTLSRYAHWVVSQPPDTYLKPLMTELLKRILDSNKRVQE 460 Query: 140 EAVVALSRLQEDTGDE 155 A A + L+E+ E Sbjct: 461 AACSAFATLEEEACTE 476 >3W9R-A nrPDB Length = 189 Score = 31.2 bits (69), Expect = 2.2, Method: Compositional matrix adjust. Identities = 15/47 (31%), Positives = 27/47 (57%), Gaps = 3/47 (6%) Query: 324 KNYTDLLDKMPEVVQL---TYYIERQYVSLRDKSSYDESCFIIEQLL 367 KNY+ +L PE+++ T IE V + ++ DE+C+ +E L+ Sbjct: 122 KNYSSILTVHPEIIEGRAGTMVIESFVVDVPQGNTKDETCYFVEALI 168 >5WTZ-A nrPDB Length = 421 Score = 30.8 bits (68), Expect = 2.7, Method: Compositional matrix adjust. Identities = 13/44 (29%), Positives = 25/44 (56%) Query: 766 ISLLGKLKIPTDLPSSDYQRTKRKLETYESHGFTMDSTSLSILA 809 + +L LK+PT+ P++ Y + L G+++ +T LSI+ Sbjct: 154 LPILVHLKLPTNTPAASYGNDEENLRVLIDQGYSLKATGLSIVT 197 >3WCG-A nrPDB Length = 365 Score = 30.0 bits (66), Expect = 4.2, Method: Compositional matrix adjust. Identities = 21/81 (25%), Positives = 38/81 (46%), Gaps = 3/81 (3%) Query: 468 PSPSLPPNELNEPEPDDMDGYKEAFNELRCLSYVQCLFENITSSLNENLYMVDMLKTLII 527 P P E+ E DD+ +K+ +E + V+CL + +L ++V+ L +L Sbjct: 217 PPRVFWPREIWEKYTDDLHAFKDELHEAKA---VECLNAMVADALVHVPHVVEYLASLRD 273 Query: 528 PAVRSHDLPIREKGLECLSLV 548 P+V + + + LSLV Sbjct: 274 PSVFAFSAIPQVMAMATLSLV 294 >2QVP-A nrPDB Length = 275 Score = 30.0 bits (66), Expect = 5.1, Method: Composition-based stats. Identities = 27/94 (28%), Positives = 42/94 (44%), Gaps = 14/94 (14%) Query: 586 LIQHGKAKFTEYEDAISSILFEALGEFENAELQTLGAEAIAKLLVILHYRDELFLKPLII 645 I++GKAK A IL E +A L +A IL +++ + + Sbjct: 131 FIENGKAKPGADTSAEGRILLE------HAHLLQ-----VASRDGILTCHEDVLMTDTYV 179 Query: 646 QYFEPNTVD---NHALRQVLGYFFPVYAFGAHEN 676 FEP+ +H+LR LG +FP+ A G +N Sbjct: 180 YTFEPSQAPGRFSHSLRDALGQYFPIAADGDVDN 213 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 5OQR-A nrPDB 1189 0.0 5OQP-A nrPDB 820 0.0 6IGX-B nrPDB 760 0.0 Sequences not found previously or not previously below threshold: 4ZDA-A nrPDB 32 0.78 5WTZ-A nrPDB 32 1.4 5D1R-A nrPDB 31 2.1 4R10-A nrPDB 30 3.3 5BPW-A nrPDB 30 3.7 3FCY-A nrPDB 30 4.0 5BNF-A nrPDB 30 4.6 4BTS-AO nrPDB 29 7.6 CONVERGED! >5OQR-A nrPDB Length = 788 Score = 1189 bits (3077), Expect = 0.0, Method: Composition-based stats. Identities = 788/823 (95%), Positives = 788/823 (95%), Gaps = 35/823 (4%) Query: 1 MSCIQIISSSQTSIAGHRKLCNKLFTLRTQEGFETDILRALNIILTVKKGNSNADRVLRF 60 MSCIQIISSSQTSIAGHRKLCNKLFTLRTQEGFETDILRALNIILTVKKGNSNADRVLRF Sbjct: 1 MSCIQIISSSQTSIAGHRKLCNKLFTLRTQEGFETDILRALNIILTVKKGNSNADRVLRF 60 Query: 61 LVTFVNYLQQKDPEIDIVQPILKHILRGLDAKDKTVRYRCCQIIARVVNCVKEIDDDLYN 120 LVTFVNYLQQKDPEIDIVQPILKHILRGLDAKDKTVRYRCCQIIARVVNCVKEIDDDLYN Sbjct: 61 LVTFVNYLQQKDPEIDIVQPILKHILRGLDAKDKTVRYRCCQIIARVVNCVKEIDDDLYN 120 Query: 121 TLKEKLLSRVLDRESIVRLEAVVALSRLQEDTGDEENDVRNILLFLLQNDPSSEVRRSVL 180 TLKEKLLSRVLDRESIVRLEAVVALSRLQEDTGDEENDVRNILLFLLQNDPSSEVRRSVL Sbjct: 121 TLKEKLLSRVLDRESIVRLEAVVALSRLQEDTGDEENDVRNILLFLLQNDPSSEVRRSVL 180 Query: 181 LNIEVSNSTLPFILERARDVDAANRKCVYARVLPKIGDFRYLSIKKRVRILKWGLNDRDE 240 LNIEVSNSTLPFILERARDVDAANRKCVYARVLPKIGDFRYLSIKKRVRILKWGLNDRDE Sbjct: 181 LNIEVSNSTLPFILERARDVDAANRKCVYARVLPKIGDFRYLSIKKRVRILKWGLNDRDE 240 Query: 241 SVEKAAADMLAYQWIENADNNLLELLERLDVSNNSDVAVLAIKKFFDVRVDSLSQLEFPE 300 SVEKAAADMLAYQWIENADNNLLELLERLDVSNNSDVAVLAIKKFFDVRVDSLSQLEFPE Sbjct: 241 SVEKAAADMLAYQWIENADNNLLELLERLDVSNNSDVAVLAIKKFFDVRVDSLSQLEFPE 300 Query: 301 QFWLELTAESSLLARTFNEICIEKNYTDLLDKMPEVVQLTYYIERQYVSLRDKSSYDESC 360 QFWLELTAESSLLARTFNEICIEKNYTDLLDKMPEVVQLTYYIERQYVSLRDKSSYDESC Sbjct: 301 QFWLELTAESSLLARTFNEICIEKNYTDLLDKMPEVVQLTYYIERQYVSLRDKSSYDESC 360 Query: 361 FIIEQLLYIGLSQDMVDEIGRRKLLKSLTNSLSTMALPDSLISLHIELLRKLCSSENDFC 420 FIIEQLLYIGLSQDMVDEIGRRKLLKSLTNSLSTMALPDSLISLHIELLRKLCSSENDFC Sbjct: 361 FIIEQLLYIGLSQDMVDEIGRRKLLKSLTNSLSTMALPDSLISLHIELLRKLCSSENDFC 420 Query: 421 SLLVEIITEVFEQGHSQNQTEEQGNSNAPELNKNDYEGEEITVSQKSPSPSLPPNELNEP 480 SLLVEIITEVFEQGHSQN PNELNEP Sbjct: 421 SLLVEIITEVFEQGHSQN-----------------------------------PNELNEP 445 Query: 481 EPDDMDGYKEAFNELRCLSYVQCLFENITSSLNENLYMVDMLKTLIIPAVRSHDLPIREK 540 EPDDMDGYKEAFNELRCLSYVQCLFENITSSLNENLYMVDMLKTLIIPAVRSHDLPIREK Sbjct: 446 EPDDMDGYKEAFNELRCLSYVQCLFENITSSLNENLYMVDMLKTLIIPAVRSHDLPIREK 505 Query: 541 GLECLSLVCLLNADLAFENVPLYLHCYEKGSVVLKCTAIRTLTDMLIQHGKAKFTEYEDA 600 GLECLSLVCLLNADLAFENVPLYLHCYEKGSVVLKCTAIRTLTDMLIQHGKAKFTEYEDA Sbjct: 506 GLECLSLVCLLNADLAFENVPLYLHCYEKGSVVLKCTAIRTLTDMLIQHGKAKFTEYEDA 565 Query: 601 ISSILFEALGEFENAELQTLGAEAIAKLLVILHYRDELFLKPLIIQYFEPNTVDNHALRQ 660 ISSILFEALGEFENAELQTLGAEAIAKLLVILHYRDELFLKPLIIQYFEPNTVDNHALRQ Sbjct: 566 ISSILFEALGEFENAELQTLGAEAIAKLLVILHYRDELFLKPLIIQYFEPNTVDNHALRQ 625 Query: 661 VLGYFFPVYAFGAHENQWRIATIFCDALLSLLEIYRDLDEDDVQLSIGHIAQQMLDWTDN 720 VLGYFFPVYAFGAHENQWRIATIFCDALLSLLEIYRDLDEDDVQLSIGHIAQQMLDWTDN Sbjct: 626 VLGYFFPVYAFGAHENQWRIATIFCDALLSLLEIYRDLDEDDVQLSIGHIAQQMLDWTDN 685 Query: 721 EKLYERKTQTGDDYIALNHNVHLHLANMIFESLPNASEGKERKFMISLLGKLKIPTDLPS 780 EKLYERKTQTGDDYIALNHNVHLHLANMIFESLPNASEGKERKFMISLLGKLKIPTDLPS Sbjct: 686 EKLYERKTQTGDDYIALNHNVHLHLANMIFESLPNASEGKERKFMISLLGKLKIPTDLPS 745 Query: 781 SDYQRTKRKLETYESHGFTMDSTSLSILAKFERMLLQNEEARS 823 SDYQRTKRKLETYESHGFTMDSTSLSILAKFERMLLQNEEARS Sbjct: 746 SDYQRTKRKLETYESHGFTMDSTSLSILAKFERMLLQNEEARS 788 >5OQP-A nrPDB Length = 869 Score = 820 bits (2119), Expect = 0.0, Method: Composition-based stats. Identities = 268/904 (29%), Positives = 442/904 (48%), Gaps = 118/904 (13%) Query: 2 SCIQIISSSQTSIAGHRK---LCNKLFTLRTQEGFETDIL----RALNIILTVKKGNSNA 54 S ++ +Q S AGHRK + K+ + ++G+E + + IL +KK N Sbjct: 12 SVAEVFQKAQGSYAGHRKHIAVLKKIQSKAVEQGYEDAFNFWFDKLVTKILPLKK-NEII 70 Query: 55 DRVLRFLVTFV-------------NYLQQKDPE---IDIVQPILKHILRGLDAKDKTVRY 98 DR+++ + F+ NY D E V ++H+LRG+++ DK VR+ Sbjct: 71 DRIVKLVAAFIASLERELILAKKQNYKLTNDEEGIFSRFVDQFIRHVLRGVESPDKNVRF 130 Query: 99 RCCQIIARVVNCVKEIDDDLYNTLKEKLLSRVLDRESIVRLEAVVALSRLQED------- 151 R Q++A +++ + EID+ L+N L L R+ DRE VR++AV L++ Q++ Sbjct: 131 RVLQLLAVIMDNIGEIDESLFNLLILSLNKRIYDREPTVRIQAVFCLTKFQDEEQTEHLT 190 Query: 152 --TGDEEN-DVRNILLFLLQNDPSSEVRRSVLLNIEVSNSTLPFILERARDVDAANRKCV 208 + +EEN + L+ +QNDPS+EVRR+ +LN+ N+T P+ILERARDV+ NR+ V Sbjct: 191 ELSDNEENFEATRTLVASIQNDPSAEVRRAAMLNLINDNNTRPYILERARDVNIVNRRLV 250 Query: 209 YARVLPKIGDFRYLSIKKRV--RILKWGLNDRDESVEKAAADMLAYQWIENADNNLLELL 266 Y+R+L +G + I+ + ++++WGL DR+ SV A ++A+ W+ D +L+ELL Sbjct: 251 YSRILKSMGRKCFDDIEPHIFDQLIEWGLEDRELSVRNACKRLIAHDWLNALDGDLIELL 310 Query: 267 ERLDVSNNSDVAVLAIKKFFDVRVDSLSQLEFPEQFWLELTAESSLLARTFNEICIEKNY 326 E+LDVS +S V V AI+ F R D LS+++FP W + T E + L R C++ N Sbjct: 311 EKLDVSRSS-VCVKAIEALFQSRPDILSKIKFP-SIWKDFTVEIAFLFRAIYLYCLDNNI 368 Query: 327 TDLLDK-MPEVVQLT----YYIERQY----VSLRDKSSYDESC--FIIEQLLYIGLSQDM 375 T++L++ PE +L+ +YI +Y +S +S +D + FIIEQL D Sbjct: 369 TEMLEENFPEASKLSEHLNHYILLRYHHNDISNDSQSHFDYNTLEFIIEQLSIAAERYDY 428 Query: 376 VDEIGRRKLLKSLTNSLSTMALPDSLISLHIELLRKLCSSENDFCSLLVEIITEVFEQGH 435 DE+GRR +L + N L+ L + LI + I +++ L +E DF ++ +EII ++ + Sbjct: 429 SDEVGRRSMLTVVRNMLALTTLSEPLIKIGIRVMKSLSINEKDFVTMAIEIINDIRDDDI 488 Query: 436 SQNQTEEQGNSNAPELNKNDYEGEEITVSQKSPSPSLPPNELNEPEPDDMDGYKEAFNEL 495 + ++E +N P + E T+ + Sbjct: 489 EKQESESDIINNLPP----EKEASSATI-------------------------------V 513 Query: 496 RCLSYVQCLFENITSSLNENLYMVDMLKTLIIPAVRSHDLPIREKGLECLSLVCLLNADL 555 CL+ + E + + L EN+ + ++ TLI PAVR+ IRE G++ L L CLL+ L Sbjct: 514 LCLTRSSYMLELVNTPLTENILIASLMDTLITPAVRNTAPNIRELGVKNLGLCCLLDVKL 573 Query: 556 AFENVPLYLHCYEKGSVVLKCTAIRTLTDMLIQHGKAKFTEYEDAISS-----ILFEALG 610 A +N+ + C KG+ LK A++ + D+ HG + E + S I ++ L Sbjct: 574 AIDNMYILGMCVSKGNASLKYIALQVIVDIFSVHGNT-VVDGEGKVDSISLHKIFYKVLK 632 Query: 611 EFENAELQTLGAEAIAKLLVILHYRDELFLKPLIIQYFEPNTVDNHALRQVLGYFFPVYA 670 E Q + AE + KL + + D+ + L++ YF P N AL Q + PVY Sbjct: 633 NNGLPECQVIAAEGLCKLFLADVFTDDDLFETLVLSYFSPINSSNEALVQAFAFCIPVYC 692 Query: 671 FGAHENQWRIATIFCDALLSLLEIYRDLD-------EDDVQLSIGHIAQQMLDWTDNEKL 723 F +Q R++ D LL L ++ DL + + L I QQ+L WTD L Sbjct: 693 FSHPAHQQRMSRTAADILLRLCVLWDDLQSSVIPEVDREAMLKPNIIFQQLLFWTDPRNL 752 Query: 724 YERKTQTGDDYIALNHNVH-LHLANMIFESLPNASEGKE-RKFMISLLGKLKIPTDLPSS 781 + T D + L + L + I E KE +K +I+ + + + ++ Sbjct: 753 VNQTGSTKKDTVQLTFLIDVLKIYAQI--------EKKEIKKMIITNINAIFLSSE---Q 801 Query: 782 DYQRTKRKLETYE--SHGFTMDSTSLSILAKFERMLLQNEEARSKFEETEEERLMENAEE 839 DY K LE + + +D+ S + L K L S EE E + +E Sbjct: 802 DYSTLKELLEYSDDIAENDNLDNVSKNALDKLRNNL------NSLIEEINERSETQTKDE 855 Query: 840 NEHA 843 N A Sbjct: 856 NNTA 859 >6IGX-B nrPDB Length = 839 Score = 760 bits (1961), Expect = 0.0, Method: Composition-based stats. Identities = 225/822 (27%), Positives = 362/822 (44%), Gaps = 133/822 (16%) Query: 1 MSCIQIISSSQTSIAGHRKLCNKL----FTLRTQEGFETDILRALNIILTVKKGNSNADR 56 +S + +Q KL L T+ + F + + L ++ V K +R Sbjct: 22 LSIKEAFRLAQQPHQNQAKLVVALSRTYRTMDDKTVFHEEFIHYLKYVMVVYKREPAVER 81 Query: 57 VLRFLVTFVNYLQQKDPEI-------DIVQPILKHILRGLDAKDKTVRYRCCQIIARVVN 109 V+ F FV Q D E ++ + +L+ +A VR+R C +I +++ Sbjct: 82 VIEFAAKFVTSFHQSDMEDDEEEEDGGLLNYLFTFLLKSHEANSNAVRFRVCLLINKLLG 141 Query: 110 CVKE---IDDDLYNTLKEKLLSRVLDRESIVRLEAVVALSRLQEDTGDEENDVRNILLFL 166 + E IDDD+++ + + +L R+ D+ VR++AV+ALSRLQ D D+E V N L Sbjct: 142 SMPENAQIDDDVFDKINKAMLIRLKDKIPNVRIQAVLALSRLQ-DPKDDECPVVNAYATL 200 Query: 167 LQNDPSSEVRRSVLLNIEVSNSTLPFILERARDVDAANRKCVYARVLPKIGDFRYLSIKK 226 ++ND + EVRR+VL I S TLP I+ R +DV A RK Y +VL + R +SI + Sbjct: 201 IENDSNPEVRRAVLSCIAPSAKTLPKIVGRTKDVKEAVRKLAY-QVLAEKVHMRAMSIAQ 259 Query: 227 RVRILKWGLNDRDESVEKAAADMLAYQWIENADNNLLELLERLDVSNNSDVAVLAIKKFF 286 RV +L+ GLNDR ++V++A L W+ ++ N+LELL RLDV N+S+VAV + F Sbjct: 260 RVMLLQQGLNDRSDAVKQAMQKHLLQGWLRFSEGNILELLHRLDVENSSEVAVSVLNALF 319 Query: 287 DVRVDSLSQLE-----------FPEQFWLELTAESSLLARTFNEICIEKN--YTDLLDK- 332 + LS+L P + LT E +L E K + L++ Sbjct: 320 S--ITPLSELVGLCKNNDGRKLIPVE---TLTPEIALYWCALCEYLKSKGDEGEEFLEQI 374 Query: 333 MPEVVQLTYYIERQYVSL-------RDKSSYDESC----FIIEQLLYIGLSQDMVDEIGR 381 +PE V Y+ S+ R SY + FI +QL+ I S D +E GR Sbjct: 375 LPEPVVYADYLLSYIQSIPVVNEEHRGDFSYIGNLMTKEFIGQQLILIIKSLDTSEEGGR 434 Query: 382 RKLLKSLTNSLSTMALPDSLISLHIELLRKLCSSENDFCSLLVEIITEVFEQGHSQNQTE 441 +KLL L L +P SL+S +E L + +N ++ EII+E+ Sbjct: 435 KKLLAVLQEILILPTIPISLVSFLVERLLHIIIDDNKRTQIVTEIISEIR---------- 484 Query: 442 EQGNSNAPELNKNDYEGEEITVSQKSPSPSLPPNELNEPEPDDMDGYKEAFNELRCLSYV 501 +TV G E +CL Sbjct: 485 ----------------APIVTV-----------------------GVAETLQ--KCLILC 503 Query: 502 QCLFENITSSLNENLYMVDMLKTLIIPAVRSHDLPIREKGLECLSLVCLLNADLAFENVP 561 L + ++ S + M ++++LI+P + S +R + CL L N D A ++ Sbjct: 504 YELLKQMSISTGLSATMNGIIESLILPGIISIHPVVRNLAVLCLGCCGLQNQDFARKHFV 563 Query: 562 LYLHCYEKGSVVLKCTAIRTLTDMLIQHGKAKF------------TEY------------ 597 L L + V +K +A++ + D L+ G F TE Sbjct: 564 LLLQVLQIDDVTIKISALKAIFDQLMTFGIEPFKTKKIKTLHCEGTEINSDDEQESKEVE 623 Query: 598 EDAISSILFEALGEF---ENAELQTLGAEAIAKLLVILHYRDELFLKPLIIQYFEPNTVD 654 E A + + + L +F E +EL+T AE +AKL+ L LI+ ++ P T + Sbjct: 624 ETATAKNVLKLLSDFLDSEVSELRTGAAEGLAKLMFSGLLVSSRILSRLILLWYNPVTEE 683 Query: 655 NHALRQVLGYFFPVYAFGAHENQWRIATIFCDALLSLLEIYRDLDEDD--VQLSIGHIAQ 712 + LR LG FFPV+A+ + NQ F +A L L+ + ++ I ++A+ Sbjct: 684 DVQLRHCLGVFFPVFAYASRTNQ----ECFEEAFLPTLQTLANAPASSPLAEIDITNVAE 739 Query: 713 QMLDWTDNEKLYERKTQTGDDYIAL--NHNVHLHLANMIFES 752 ++D T L + +T DY AL + N+ + + N I S Sbjct: 740 LLVDLTRPSGL-NPQAKTSQDYQALTVHDNLAMKICNEILTS 780 >4ZDA-A nrPDB Length = 767 Score = 32.4 bits (72), Expect = 0.78, Method: Composition-based stats. Identities = 32/168 (19%), Positives = 66/168 (39%), Gaps = 20/168 (11%) Query: 195 ERARDVDAANRKCVYARVLPKIGDFR---------YLSIKKRVRIL-----KWGLNDRDE 240 R +D A N + ++R+ ++ +F + V ++ ++G +D+ Sbjct: 370 GRTKDTKAVNPESTFSRMYQEMINFCKTHGQFDPTTMGTVPNVGLMAQKAEEYGSHDKTF 429 Query: 241 SV-EKAAADMLAYQWIENADNNLLELLERLDVSNNSDVAVLAIKKFFDVRVDSLSQLEFP 299 + E AD++ I+ + L + +E D+ V I+ + + V P Sbjct: 430 EIPEDGVADIVD---IDTGEVLLTQNVEEGDIWRMPIVKDAPIRDWVKLAVTRARLSGMP 486 Query: 300 EQFWLELT-AESSLLARTFNEICIEKNYTDL-LDKMPEVVQLTYYIER 345 FWL+ L + E + + L + MP+V + Y +ER Sbjct: 487 VVFWLDTERPHEVELRKKVKEYLKDHDTEGLKIQIMPQVWAMRYTLER 534 >5WTZ-A nrPDB Length = 421 Score = 31.6 bits (70), Expect = 1.4, Method: Composition-based stats. Identities = 13/43 (30%), Positives = 25/43 (58%) Query: 766 ISLLGKLKIPTDLPSSDYQRTKRKLETYESHGFTMDSTSLSIL 808 + +L LK+PT+ P++ Y + L G+++ +T LSI+ Sbjct: 154 LPILVHLKLPTNTPAASYGNDEENLRVLIDQGYSLKATGLSIV 196 >5D1R-A nrPDB Length = 239 Score = 31.3 bits (69), Expect = 2.1, Method: Composition-based stats. Identities = 26/133 (19%), Positives = 48/133 (36%), Gaps = 8/133 (6%) Query: 365 QLLYIGLSQDMVD-------EIGRRKLLKSLTNSLSTMALPDSLISLHIELLRKLCSSEN 417 Q +G +D + E+GRR+LL LS A+ +L + + R + S + Sbjct: 3 QTCRVGKRRDAREQIEAKIVELGRRQLLDHGAAGLSLRAIARNLGMVSSAVYRYVSSRDE 62 Query: 418 DFCSLLVEIITEVFEQ-GHSQNQTEEQGNSNAPELNKNDYEGEEITVSQKSPSPSLPPNE 476 LLV+ +++ + +++ T S+ G +T + P Sbjct: 63 LLTLLLVDAYSDLADTVDRARDDTVADSWSDDVIAIARAVRGWAVTNPARWALLYGSPVP 122 Query: 477 LNEPEPDDMDGYK 489 PD G Sbjct: 123 GYHAPPDRTAGVA 135 >4R10-A nrPDB Length = 572 Score = 30.5 bits (67), Expect = 3.3, Method: Composition-based stats. Identities = 63/372 (16%), Positives = 122/372 (32%), Gaps = 48/372 (12%) Query: 361 FIIEQLLYIGLSQDMVDEIGRRKLLKSLTNSLSTMALPD---SLISLHI--ELLRKLCSS 415 + Q+L L + D R+ + + S P +LISL L +LC++ Sbjct: 197 LLGPQILVSILR-EYSDH--RKLIYTVVRCIRSLSVCPSNKPALISLGCLPALYVELCTA 253 Query: 416 ENDFCSLLVEIITEVFEQGHSQNQTEEQGNSNAPELNKNDYEGEEITVSQKSPSPSLPPN 475 +++ + + + + Q E+ + +G + + S N Sbjct: 254 KDERSQTAILVAMRNLSDSATNEENLTQLIIKLLEIIRVANDGMTAC-ACGTLSNLTCNN 312 Query: 476 ELNEPEPDDMDGYKEAFNELRCLSYVQCLFE---------NITSSLNENL---------- 516 N+ G +R L V+ + E SL E Sbjct: 313 TRNKQTVCSHGGIDALVTAIRRLPEVEEVTEPALCALRHCTARHSLAEEAQSELRFCQAF 372 Query: 517 -YMVDMLKTLIIPAVRSHDLPIREKGLECLSLVCLLNADLAFENVPLYLHCYEKGSVVLK 575 ++D L+TL P +++ IR L +L+ L A + + L + Sbjct: 373 PVILDQLETLRTPVIKAALGVIRNSALLQTNLIELTQEQTANGHTAVSL---TMDILRRA 429 Query: 576 CTAIRTLTDMLIQHGKAKFTEYEDAISSILFEA------------LGEFENAELQTLGAE 623 TAI D+ G + E A+S++ A +G+ N E + Sbjct: 430 ITAIEENPDI-AVDGVPMWGVIEGAVSALHQLANHPAVAAACCDDIGQVGNPECPPF-LD 487 Query: 624 AIAKLLVILHY--RDELFLKPLIIQYFEPNTVDNHALRQVLGYFFPVYAFGAHENQWRIA 681 + +LL D+ L+ I+ + R V + +Q++ Sbjct: 488 LLHRLLAHPRLGSMDDEVLEREILGLLYQLSKRPDGARAVESTGVSALLMESRGSQYKSV 547 Query: 682 TIFCDALLSLLE 693 + + +LS L+ Sbjct: 548 VTYANGVLSNLK 559 >5BPW-A nrPDB Length = 843 Score = 30.5 bits (67), Expect = 3.7, Method: Composition-based stats. Identities = 18/51 (35%), Positives = 30/51 (58%), Gaps = 1/51 (1%) Query: 821 ARSKFEETEEERLMENAEENEHAGAEAISGEIIPDTVEANME-DEEEVYVK 870 A +K + +EE L E+ EN+ AGA A++ EI+ + + E D E +Y + Sbjct: 764 ASNKPVKIKEEVLSESEAENQQAGAAALAPEIVIKVEKLDPELDSENLYFQ 814 >3FCY-A nrPDB Length = 346 Score = 30.1 bits (66), Expect = 4.0, Method: Composition-based stats. Identities = 12/38 (31%), Positives = 21/38 (55%), Gaps = 4/38 (10%) Query: 84 HILRGLDAKDKTVRYRCCQI----IARVVNCVKEIDDD 117 HI+RGLD + +R + +A +V + E+D+D Sbjct: 163 HIIRGLDDDADNMLFRHIFLDTAQLAGIVMNMPEVDED 200 >5BNF-A nrPDB Length = 232 Score = 30.1 bits (66), Expect = 4.6, Method: Composition-based stats. Identities = 18/95 (18%), Positives = 40/95 (42%), Gaps = 3/95 (3%) Query: 658 LRQVLGYFFPVYAFGAHENQWRIATIFCDALLSLLEIYRDLDEDDVQLSIGHIA---QQM 714 LR+ Y V + +I F DA +S ++ D+ + +GH + Sbjct: 15 LRRCYTYIRVVQPELGDRDCQKIKKAFTDAFISKDPCSAREEDYDLLMKLGHQTVPCDKT 74 Query: 715 LDWTDNEKLYERKTQTGDDYIALNHNVHLHLANMI 749 + W+ ++L + T+T L + + ++A+ + Sbjct: 75 VFWSKTKELAHQYTKTQKGLFTLENTLLGYIADDL 109 >4BTS-AO nrPDB Length = 153 Score = 29.3 bits (64), Expect = 7.6, Method: Composition-based stats. Identities = 16/53 (30%), Positives = 26/53 (49%), Gaps = 9/53 (16%) Query: 96 VRYRCCQIIARVV---NCVKEIDDDLYNTLKEKLLSRV------LDRESIVRL 139 VR+ Q I R++ C ++ +DLY +K+ L R D++S RL Sbjct: 65 VRFLTGQKILRILKKNGCAPQLPEDLYFLIKKALSIRKHLEKNRKDKDSKYRL 117 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.312 0.127 0.316 Lambda K H 0.267 0.0392 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 28,545,376 Number of Sequences: 36641 Number of extensions: 1097656 Number of successful extensions: 3204 Number of sequences better than 10.0: 15 Number of HSP's better than 10.0 without gapping: 14 Number of HSP's successfully gapped in prelim test: 17 Number of HSP's that attempted gapping in prelim test: 3131 Number of HSP's gapped (non-prelim): 46 length of query: 875 length of database: 10,336,785 effective HSP length: 106 effective length of query: 769 effective length of database: 6,452,839 effective search space: 4962233191 effective search space used: 4962233191 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.4 bits) S2: 63 (28.9 bits)